# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DDE_3 PF13358.6 EHT97532.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHT97532.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHT97532.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHT97532.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHT97532.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHT97532.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHT97532.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHT97532.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 Topoisom_bac PF01131.20 EHT97535.1 - 2.8e-86 290.1 0.0 3.8e-86 289.7 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim_Crpt PF13342.6 EHT97535.1 - 5.4e-17 61.5 1.5 1.2e-16 60.4 0.8 2.0 2 0 0 2 2 2 1 C-terminal repeat of topoisomerase Toprim PF01751.22 EHT97535.1 - 2.7e-15 56.5 0.0 5.8e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Toprim domain zf-C4_Topoisom PF01396.19 EHT97535.1 - 4e-08 32.9 3.9 4e-08 32.9 3.9 2.7 2 0 0 2 2 2 1 Topoisomerase DNA binding C4 zinc finger SSB PF00436.25 EHT97536.1 - 2.9e-41 139.7 0.5 3.9e-41 139.3 0.5 1.2 1 0 0 1 1 1 1 Single-strand binding protein family DnaJ PF00226.31 EHT97538.1 - 5.5e-14 52.0 2.0 1.9e-13 50.3 0.3 2.2 2 0 0 2 2 2 1 DnaJ domain DegS PF05384.11 EHT97538.1 - 0.46 10.0 4.8 6.4 6.2 0.1 3.4 2 1 2 4 4 4 0 Sensor protein DegS MqsA_antitoxin PF15731.5 EHT97541.1 - 0.0091 16.1 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 Antitoxin component of bacterial toxin-antitoxin system, MqsA HTH_19 PF12844.7 EHT97541.1 - 0.012 15.6 0.2 1.5 8.9 0.0 2.4 2 1 0 2 2 2 0 Helix-turn-helix domain AAA_13 PF13166.6 EHT97541.1 - 0.016 13.9 0.0 0.018 13.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain HTH_31 PF13560.6 EHT97541.1 - 0.074 13.4 0.1 0.25 11.7 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain MAGE PF01454.19 EHT97541.1 - 0.082 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 MAGE family DUF4264 PF14084.6 EHT97541.1 - 0.096 12.3 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) tRNA_NucTran2_2 PF13735.6 EHT97542.1 - 0.069 13.1 0.1 0.07 13.1 0.1 1.1 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative DUF5638 PF18688.1 EHT97543.1 - 0.007 16.7 0.0 0.0082 16.4 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5638) HicB_lk_antitox PF15919.5 EHT97545.1 - 1.9e-16 60.3 0.0 2.2e-16 60.1 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system CCCAP PF15964.5 EHT97547.1 - 0.00092 17.6 6.6 0.0012 17.3 6.6 1.0 1 0 0 1 1 1 1 Centrosomal colon cancer autoantigen protein family ThrE PF06738.12 EHT97547.1 - 0.004 16.5 0.1 0.0058 16.0 0.1 1.4 1 1 0 1 1 1 1 Putative threonine/serine exporter Baculo_PEP_C PF04513.12 EHT97547.1 - 0.011 15.8 5.6 0.051 13.6 0.3 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2730 PF10805.8 EHT97547.1 - 0.015 15.4 3.3 2.4 8.3 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) CARMIL_C PF16000.5 EHT97547.1 - 0.065 12.9 1.7 0.076 12.6 1.4 1.3 1 1 0 1 1 1 0 CARMIL C-terminus Prominin PF05478.11 EHT97547.1 - 0.067 11.2 5.2 0.078 10.9 4.5 1.4 1 1 0 1 1 1 0 Prominin Nup88 PF10168.9 EHT97547.1 - 0.11 10.3 5.2 0.13 10.0 5.2 1.0 1 0 0 1 1 1 0 Nuclear pore component SlyX PF04102.12 EHT97547.1 - 0.13 12.9 2.6 0.61 10.7 0.4 2.4 1 1 0 2 2 2 0 SlyX DUF4618 PF15397.6 EHT97547.1 - 0.15 11.5 8.1 0.072 12.5 0.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Sas10_Utp3 PF04000.15 EHT97547.1 - 0.17 12.5 4.1 8.1 7.1 0.0 3.1 2 1 0 2 2 2 0 Sas10/Utp3/C1D family CREPT PF16566.5 EHT97547.1 - 0.33 11.1 5.9 0.63 10.2 3.8 2.0 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF5082 PF16888.5 EHT97547.1 - 0.36 11.1 9.0 0.77 10.1 1.1 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) DASH_Duo1 PF08651.10 EHT97547.1 - 0.36 10.6 5.1 3.3 7.6 0.4 2.8 2 1 0 2 2 2 0 DASH complex subunit Duo1 NPV_P10 PF05531.12 EHT97547.1 - 0.44 11.0 5.1 5.8 7.5 0.7 2.4 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein COG5 PF10392.9 EHT97547.1 - 0.47 10.6 8.3 0.49 10.6 4.5 2.1 1 1 1 2 2 2 0 Golgi transport complex subunit 5 DUF4446 PF14584.6 EHT97547.1 - 0.63 10.0 6.1 1.6 8.7 1.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DUF1870 PF08965.10 EHT97547.1 - 0.7 9.9 4.1 5 7.2 2.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1870) DUF16 PF01519.16 EHT97547.1 - 1.7 9.2 7.2 7.9 7.0 7.2 2.0 1 1 0 1 1 1 0 Protein of unknown function DUF16 Fzo_mitofusin PF04799.13 EHT97547.1 - 2.4 7.7 7.4 1.2 8.7 0.3 2.3 1 1 1 2 2 2 0 fzo-like conserved region DUF4665 PF15679.5 EHT97547.1 - 4.1 8.1 7.1 2.4 8.8 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4665) FlaC_arch PF05377.11 EHT97547.1 - 7.2 7.1 9.4 12 6.3 0.7 3.2 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) YabA PF06156.13 EHT97547.1 - 7.3 7.3 6.6 12 6.5 0.5 2.5 1 1 1 2 2 2 0 Initiation control protein YabA DUF1874 PF08960.10 EHT97548.1 - 0.0071 16.5 2.2 0.39 10.9 0.2 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF1874) MMR_HSR1 PF01926.23 EHT97548.1 - 0.0092 16.1 0.4 0.019 15.0 0.4 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.6 EHT97548.1 - 0.024 14.7 0.9 0.079 13.0 0.1 2.1 1 1 1 2 2 2 0 AAA domain CbiA PF01656.23 EHT97548.1 - 0.27 11.3 4.3 1.9 8.6 4.3 2.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MobC PF05713.11 EHT97550.1 - 0.015 15.8 0.8 0.031 14.8 0.8 1.5 1 0 0 1 1 1 0 Bacterial mobilisation protein (MobC) MRP_L53 PF10780.9 EHT97550.1 - 0.047 13.9 0.1 1.3 9.3 0.0 2.4 2 0 0 2 2 2 0 39S ribosomal protein L53/MRP-L53 LPD7 PF18821.1 EHT97551.1 - 3.3e-15 56.0 0.1 2e-14 53.4 0.0 2.4 2 0 0 2 2 2 1 Large polyvalent protein-associated domain 7 Relaxase PF03432.14 EHT97551.1 - 2.5e-05 24.0 2.6 2.5e-05 24.0 2.6 2.4 2 0 0 2 2 2 1 Relaxase/Mobilisation nuclease domain PhdYeFM_antitox PF02604.19 EHT97552.1 - 4.6e-07 29.5 0.0 5.8e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system MEDS PF14417.6 EHT97552.1 - 0.052 13.4 0.0 0.054 13.3 0.0 1.2 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain IncFII_repA PF02387.15 EHT97553.1 - 4e-12 46.0 0.0 5.5e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 IncFII RepA protein family Homeobox_KN PF05920.11 EHT97553.1 - 0.051 13.5 0.8 0.12 12.3 0.8 1.6 1 0 0 1 1 1 0 Homeobox KN domain IGPS PF00218.21 EHT97554.1 - 0.008 15.4 0.1 0.0089 15.2 0.1 1.1 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase Lambda_tail_I PF06805.12 EHT97554.1 - 0.15 12.4 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage lambda tail assembly protein I MipZ PF09140.11 EHT97558.1 - 3.9e-14 52.6 0.2 1.1e-07 31.4 0.0 2.4 1 1 1 2 2 2 2 ATPase MipZ AAA_31 PF13614.6 EHT97558.1 - 1.3e-10 41.5 0.0 3.5e-05 23.8 0.0 2.1 1 1 0 2 2 2 2 AAA domain CbiA PF01656.23 EHT97558.1 - 1.1e-08 35.2 0.0 1.3e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain GTP_EFTU PF00009.27 EHT97558.1 - 7.1e-06 25.7 0.0 8.9e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain VirC1 PF07015.11 EHT97558.1 - 6.3e-05 22.4 0.0 8.9e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 VirC1 protein ParA PF10609.9 EHT97558.1 - 0.00011 21.8 0.1 0.00017 21.1 0.1 1.3 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 EHT97558.1 - 0.0038 16.7 0.1 0.0099 15.4 0.0 1.7 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ ArsA_ATPase PF02374.15 EHT97558.1 - 0.011 14.9 0.0 0.022 14.0 0.0 1.5 1 1 0 1 1 1 0 Anion-transporting ATPase Fer4_NifH PF00142.18 EHT97558.1 - 0.039 13.4 0.0 0.074 12.5 0.0 1.4 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Phage_integrase PF00589.22 EHT97559.1 - 7.1e-26 91.0 0.0 1.1e-25 90.4 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family GHL6 PF14871.6 EHT97559.1 - 0.062 13.4 0.0 0.091 12.9 0.0 1.2 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 MethyltransfD12 PF02086.15 EHT97561.1 - 9e-23 81.3 0.0 1.3e-22 80.7 0.0 1.3 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase HTH_3 PF01381.22 EHT97561.1 - 0.075 13.1 0.3 0.22 11.6 0.3 1.8 1 0 0 1 1 1 0 Helix-turn-helix Phage_cap_E PF03864.15 EHT97562.1 - 0.0092 15.2 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 Phage major capsid protein E HTH_3 PF01381.22 EHT97564.1 - 0.017 15.2 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix HTH_31 PF13560.6 EHT97564.1 - 0.019 15.3 0.0 0.032 14.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_26 PF13443.6 EHT97564.1 - 0.071 13.5 0.1 0.13 12.8 0.1 1.3 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain DUF3408 PF11888.8 EHT97566.1 - 0.00048 20.3 0.0 0.00056 20.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3408) RepB PF07506.11 EHT97566.1 - 0.053 13.6 0.0 0.055 13.6 0.0 1.0 1 0 0 1 1 1 0 RepB plasmid partitioning protein CagE_TrbE_VirB PF03135.14 EHT97567.1 - 1.3e-18 67.8 0.0 2.1e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system NEL PF14496.6 EHT97567.1 - 0.085 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 C-terminal novel E3 ligase, LRR-interacting DDE_3 PF13358.6 EHT97568.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHT97568.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHT97568.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHT97568.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHT97568.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHT97568.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHT97568.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHT97568.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 AAA_30 PF13604.6 EHT97569.1 - 1.5e-20 73.7 0.3 2e-20 73.3 0.3 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EHT97569.1 - 1.1e-08 35.5 0.0 1.6e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EHT97569.1 - 0.056 13.2 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 EHT97569.1 - 0.12 12.2 0.1 5.1 6.9 0.1 2.2 1 1 0 2 2 2 0 Helicase DUF3396 PF11876.8 EHT97569.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3396) AAA_22 PF13401.6 EHT97569.1 - 0.14 12.4 0.0 0.44 10.8 0.0 1.9 2 1 0 2 2 2 0 AAA domain PIF1 PF05970.14 EHT97569.1 - 0.15 11.2 0.0 0.81 8.8 0.1 2.1 2 1 0 2 2 2 0 PIF1-like helicase DDE_Tnp_IS66 PF03050.14 EHT97570.1 - 2.7e-97 325.7 4.0 1.2e-96 323.5 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT97570.1 - 3.3e-16 59.2 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT97570.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT97570.1 - 8.7e-11 42.4 9.0 1.9e-10 41.4 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Phage_HK97_TLTM PF06120.11 EHT97570.1 - 0.011 15.0 0.8 0.021 14.0 0.8 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHT97570.1 - 0.02 15.2 4.2 0.084 13.2 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain UME PF08064.13 EHT97570.1 - 0.032 14.1 0.3 20 5.1 0.0 3.1 2 1 1 3 3 3 0 UME (NUC010) domain Exonuc_VII_L PF02601.15 EHT97570.1 - 0.039 13.5 2.7 0.04 13.5 1.0 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Troponin PF00992.20 EHT97570.1 - 0.044 14.1 2.8 0.078 13.3 2.8 1.3 1 0 0 1 1 1 0 Troponin FUSC PF04632.12 EHT97570.1 - 0.048 12.2 7.4 0.077 11.5 7.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tho2 PF11262.8 EHT97570.1 - 0.049 12.8 0.6 0.081 12.1 0.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FAM184 PF15665.5 EHT97570.1 - 0.052 13.3 8.0 0.082 12.7 8.0 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B HalX PF08663.10 EHT97570.1 - 0.13 12.6 2.4 0.34 11.3 2.4 1.7 1 0 0 1 1 1 0 HalX domain LXG PF04740.12 EHT97570.1 - 0.14 11.8 2.8 0.35 10.5 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHT97570.1 - 0.19 11.5 11.1 0.31 10.8 11.1 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DHR10 PF18595.1 EHT97570.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Zn-ribbon_8 PF09723.10 EHT97570.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF1192 PF06698.11 EHT97570.1 - 0.54 10.4 5.3 3.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHT97570.1 - 0.82 8.9 3.0 1.2 8.3 3.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHT97570.1 - 2 8.0 8.1 4.3 6.8 8.1 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHT97570.1 - 4.2 7.7 8.6 8.7 6.7 8.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CREPT PF16566.5 EHT97570.1 - 5.9 7.1 8.7 2.7 8.1 5.6 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour SlyX PF04102.12 EHT97570.1 - 9.7 6.9 9.0 18 6.1 2.3 3.0 1 1 1 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHT97571.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHT97572.1 - 2.7e-10 40.4 0.0 5.1e-10 39.5 0.0 1.5 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.6 EHT97572.1 - 0.0054 16.5 0.0 0.0072 16.1 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 EHT97572.1 - 0.028 14.5 0.0 0.044 13.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Transposase_20 PF02371.16 EHT97573.1 - 4.6e-20 71.7 0.2 9.8e-20 70.7 0.2 1.6 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family DEDD_Tnp_IS110 PF01548.17 EHT97573.1 - 2.6e-19 69.6 0.1 1.2e-18 67.4 0.0 1.9 2 0 0 2 2 2 1 Transposase DUF4635 PF15466.6 EHT97573.1 - 0.11 12.1 0.9 9.2 5.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) LysR_substrate PF03466.20 EHT97574.1 - 8.7e-30 103.6 3.0 1.2e-29 103.2 3.0 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EHT97574.1 - 3.2e-21 75.0 0.2 3.2e-21 75.0 0.2 2.5 3 1 1 4 4 4 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 EHT97574.1 - 0.039 13.8 0.4 0.15 12.0 0.4 2.0 1 0 0 1 1 1 0 MarR family DUF2065 PF09838.9 EHT97574.1 - 2.6 8.1 9.4 4.2 7.5 0.1 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2065) Cupin_2 PF07883.11 EHT97575.1 - 2.8e-18 65.4 0.2 3.9e-18 64.9 0.2 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EHT97575.1 - 2.1e-08 33.9 0.0 3.2e-08 33.3 0.0 1.3 1 1 0 1 1 1 1 Cupin AraC_binding PF02311.19 EHT97575.1 - 1e-06 28.7 0.1 1.2e-06 28.5 0.1 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 EHT97575.1 - 5.3e-06 26.0 0.0 7.4e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_7 PF12973.7 EHT97575.1 - 0.00057 19.8 0.2 0.001 18.9 0.2 1.5 1 1 0 1 1 1 1 ChrR Cupin-like domain Cupin_6 PF12852.7 EHT97575.1 - 0.001 18.8 0.0 0.0011 18.7 0.0 1.1 1 0 0 1 1 1 1 Cupin MannoseP_isomer PF01050.18 EHT97575.1 - 0.027 14.4 0.0 0.028 14.3 0.0 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase DMSP_lyase PF16867.5 EHT97575.1 - 0.074 12.7 0.0 0.094 12.4 0.0 1.1 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase 3-HAO PF06052.12 EHT97575.1 - 0.083 12.5 0.0 0.091 12.4 0.0 1.1 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase ARD PF03079.14 EHT97575.1 - 0.19 11.9 0.0 0.26 11.5 0.0 1.2 1 0 0 1 1 1 0 ARD/ARD' family Transposase_20 PF02371.16 EHT97576.1 - 4.5e-20 71.7 0.1 1.1e-19 70.5 0.1 1.7 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family DEDD_Tnp_IS110 PF01548.17 EHT97576.1 - 1.3e-19 70.6 0.2 1.3e-18 67.3 0.0 2.5 3 0 0 3 3 3 1 Transposase MCRS_N PF13325.6 EHT97576.1 - 0.079 13.0 0.5 0.14 12.2 0.5 1.3 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein DUF4635 PF15466.6 EHT97576.1 - 0.18 11.3 1.4 9.7 5.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) MobC PF05713.11 EHT97577.1 - 2.1e-13 50.5 1.6 2.9e-13 50.0 1.6 1.2 1 0 0 1 1 1 1 Bacterial mobilisation protein (MobC) Pentapeptide PF00805.22 EHT97579.1 - 3.4e-70 231.1 62.6 4.1e-14 51.9 8.5 6.4 2 1 3 6 6 6 6 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 EHT97579.1 - 6.5e-35 119.1 2.7 2.2e-11 43.8 0.1 3.6 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 EHT97579.1 - 1.6e-26 92.2 0.0 6.2e-05 23.1 0.0 5.9 1 1 4 5 5 5 4 Pentapeptide repeats (9 copies) DNA_ligase_OB PF03120.16 EHT97579.1 - 0.0018 18.2 3.3 24 4.9 0.1 5.7 1 1 3 4 4 4 1 NAD-dependent DNA ligase OB-fold domain CfAFP PF05264.11 EHT97579.1 - 0.11 12.5 1.8 13 5.8 0.0 3.5 2 1 3 5 5 5 0 Choristoneura fumiferana antifreeze protein (CfAFP) KIAA1328 PF15369.6 EHT97579.1 - 0.16 11.8 2.6 2.2 8.0 0.3 2.3 1 1 1 2 2 2 0 Uncharacterised protein KIAA1328 PapC_N PF13954.6 EHT97579.1 - 0.23 11.5 3.3 14 5.6 0.4 3.1 1 1 2 3 3 3 0 PapC N-terminal domain Relaxase PF03432.14 EHT97580.1 - 9.6e-19 67.9 0.0 2.1e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 Relaxase/Mobilisation nuclease domain MobC PF05713.11 EHT97581.1 - 2.1e-13 50.5 1.6 2.9e-13 50.0 1.6 1.2 1 0 0 1 1 1 1 Bacterial mobilisation protein (MobC) HTH_Tnp_1 PF01527.20 EHT97582.1 - 2.6e-15 56.5 0.0 1.6e-14 53.9 0.0 2.2 2 1 0 2 2 2 1 Transposase HTH_23 PF13384.6 EHT97582.1 - 1.4e-06 27.9 0.0 0.017 14.9 0.0 2.3 2 0 0 2 2 2 2 Homeodomain-like domain HTH_28 PF13518.6 EHT97582.1 - 0.0034 17.5 0.0 0.66 10.2 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain MarR_2 PF12802.7 EHT97582.1 - 0.054 13.4 0.1 0.68 9.9 0.0 2.3 2 0 0 2 2 2 0 MarR family LZ_Tnp_IS481 PF13011.6 EHT97582.1 - 0.084 13.4 0.2 3.4 8.3 0.0 2.6 3 0 0 3 3 3 0 leucine-zipper of insertion element IS481 TnpB_IS66 PF05717.13 EHT97583.1 - 2.7e-05 24.0 0.0 2.9e-05 23.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein MPTase-PolyVal PF18818.1 EHT97585.1 - 7.1e-48 161.8 0.0 2.8e-47 159.9 0.0 2.1 1 0 0 1 1 1 1 Metallopeptidase superfamily domain DUF1738 PF08401.11 EHT97585.1 - 2e-32 112.0 2.0 2.5e-32 111.7 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1738) Toprim_3 PF13362.6 EHT97585.1 - 2e-07 31.3 8.2 7.2e-07 29.5 0.1 4.3 3 0 0 3 3 3 1 Toprim domain EpmC PF04315.12 EHT97585.1 - 0.061 13.0 0.1 0.061 13.0 0.1 2.4 2 0 0 2 2 2 0 Elongation factor P hydroxylase Topoisom_bac PF01131.20 EHT97587.1 - 5.1e-111 371.6 0.0 6.1e-111 371.4 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 EHT97587.1 - 7.9e-18 64.6 0.0 1.9e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 Toprim domain zf-C4_Topoisom PF01396.19 EHT97587.1 - 4.2e-07 29.6 2.9 8.3e-07 28.7 2.9 1.5 1 0 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger Zn_ribbon_recom PF13408.6 EHT97587.1 - 0.058 13.9 0.8 0.12 12.9 0.8 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Peptidase_S26 PF10502.9 EHT97588.1 - 8e-44 148.8 0.0 1e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 T4SS-DNA_transf PF02534.14 EHT97589.1 - 1.7e-150 501.9 0.0 2e-150 501.7 0.0 1.0 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer TraG-D_C PF12696.7 EHT97589.1 - 1.5e-32 112.2 0.0 2.3e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 EHT97589.1 - 7.2e-23 81.1 0.0 2.3e-22 79.4 0.0 1.6 1 1 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain Phage_GPD PF05954.11 EHT97590.1 - 2.3e-12 46.8 0.1 3.5e-12 46.2 0.1 1.2 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) Phage_base_V PF04717.12 EHT97591.1 - 5.9e-19 68.0 0.0 8.5e-19 67.5 0.0 1.2 1 0 0 1 1 1 1 Type VI secretion system, phage-baseplate injector DUF4998 PF16389.5 EHT97591.1 - 0.034 13.8 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function GPW_gp25 PF04965.14 EHT97592.1 - 5.3e-10 38.9 0.0 6.3e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Gene 25-like lysozyme DUF2634 PF10934.8 EHT97592.1 - 0.0061 16.6 0.0 0.0079 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2634) Baseplate_J PF04865.14 EHT97593.1 - 2.5e-73 246.4 0.5 3.8e-73 245.8 0.5 1.3 1 0 0 1 1 1 1 Baseplate J-like protein Tail_P2_I PF09684.10 EHT97594.1 - 9.3e-28 96.9 0.0 1.1e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Phage tail protein (Tail_P2_I) SWI2_SNF2 PF18766.1 EHT97595.1 - 0.013 15.2 0.0 0.066 12.9 0.0 1.9 1 1 1 2 2 2 0 SWI2/SNF2 ATPase MarR_2 PF12802.7 EHT97595.1 - 0.021 14.7 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.20 EHT97595.1 - 0.18 12.2 0.1 0.55 10.6 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator Caudo_TAP PF02413.17 EHT97596.1 - 2.5e-24 85.9 0.1 2.9e-24 85.7 0.1 1.0 1 0 0 1 1 1 1 Caudovirales tail fibre assembly protein, lambda gpK Caudo_TAP PF02413.17 EHT97597.1 - 1.3e-12 48.0 0.1 1.4e-12 47.9 0.1 1.0 1 0 0 1 1 1 1 Caudovirales tail fibre assembly protein, lambda gpK DUF469 PF04320.14 EHT97597.1 - 0.011 16.5 0.1 0.012 16.5 0.1 1.0 1 0 0 1 1 1 0 Protein with unknown function (DUF469) Resolvase PF00239.21 EHT97598.1 - 6.8e-45 152.8 0.2 1e-44 152.2 0.2 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_7 PF02796.15 EHT97598.1 - 3.4e-13 49.4 0.1 1.5e-12 47.4 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 EHT97598.1 - 0.0071 16.1 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 EHT97598.1 - 0.014 16.0 0.2 0.026 15.1 0.2 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_38 PF13936.6 EHT97598.1 - 0.018 14.8 0.1 0.083 12.7 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_4 PF13613.6 EHT97598.1 - 0.022 14.5 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_29 PF13551.6 EHT97598.1 - 0.067 13.2 1.8 0.4 10.7 0.1 2.4 1 1 1 2 2 2 0 Winged helix-turn helix HTH_psq PF05225.16 EHT97598.1 - 0.069 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 helix-turn-helix, Psq domain adh_short PF00106.25 EHT97599.1 - 4.6e-22 78.4 0.0 5.2e-22 78.3 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EHT97599.1 - 9.9e-20 71.1 0.1 1.2e-19 70.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EHT97599.1 - 3.8e-07 30.2 0.0 4.1e-07 30.1 0.0 1.0 1 0 0 1 1 1 1 KR domain LytR_C PF13399.6 EHT97599.1 - 0.038 15.0 0.1 0.058 14.4 0.1 1.4 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator Epimerase PF01370.21 EHT97599.1 - 0.042 13.3 0.0 0.046 13.2 0.0 1.0 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EHT97599.1 - 0.18 11.2 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase KMP11 PF03037.16 EHT97600.1 - 0.027 15.3 0.4 0.027 15.2 0.4 1.0 1 0 0 1 1 1 0 Kinetoplastid membrane protein 11 IstB_IS21 PF01695.17 EHT97603.1 - 2.2e-19 69.9 0.0 3e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein Bac_DnaA PF00308.18 EHT97603.1 - 3.1e-08 33.8 0.0 3.9e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Bacterial dnaA protein RuvB_N PF05496.12 EHT97603.1 - 0.0082 15.9 0.0 0.021 14.6 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 EHT97603.1 - 0.0087 16.5 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.10 EHT97603.1 - 0.037 13.5 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_5 PF07728.14 EHT97603.1 - 0.079 13.0 0.2 0.66 10.0 0.2 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EHT97603.1 - 0.12 12.1 0.1 0.45 10.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain CbiA PF01656.23 EHT97603.1 - 0.12 12.4 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PIF1 PF05970.14 EHT97603.1 - 0.12 11.5 0.2 0.46 9.6 0.1 1.8 1 1 1 2 2 2 0 PIF1-like helicase Rep_3 PF01051.21 EHT97606.1 - 8.6e-26 91.1 11.8 9.9e-26 90.9 11.8 1.0 1 0 0 1 1 1 1 Initiator Replication protein 40S_S4_C PF16121.5 EHT97606.1 - 0.096 12.3 0.6 0.21 11.2 0.6 1.5 1 0 0 1 1 1 0 40S ribosomal protein S4 C-terminus DDE_3 PF13358.6 EHT97608.1 - 1.2e-22 80.2 0.0 2e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 EHT97608.1 - 1.2e-10 40.9 1.0 3.6e-09 36.2 0.1 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 EHT97608.1 - 2.9e-09 37.4 0.5 2.5e-08 34.4 0.1 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 EHT97608.1 - 4.1e-07 29.9 1.2 1.1e-06 28.6 0.3 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_33 PF13592.6 EHT97608.1 - 4.8e-06 26.1 0.2 4.8e-06 26.1 0.2 2.6 3 0 0 3 3 3 1 Winged helix-turn helix HTH_28 PF13518.6 EHT97608.1 - 1.4e-05 25.1 0.3 0.0002 21.4 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHT97608.1 - 0.031 14.8 0.2 0.062 13.8 0.2 1.4 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 HTH_38 PF13936.6 EHT97608.1 - 0.053 13.3 0.6 0.16 11.8 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain DUF2726 PF10881.8 EHT97609.1 - 0.025 14.4 0.0 0.03 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) TraY PF05509.11 EHT97611.1 - 9.6e-05 22.3 0.1 0.00027 20.9 0.1 1.9 1 1 0 1 1 1 1 TraY domain RHH_1 PF01402.21 EHT97611.1 - 0.00047 20.0 0.3 0.0016 18.3 0.0 2.0 2 0 0 2 2 2 1 Ribbon-helix-helix protein, copG family BST2 PF16716.5 EHT97611.1 - 0.034 14.7 1.2 0.058 14.0 0.7 1.6 1 1 0 1 1 1 0 Bone marrow stromal antigen 2 ParG PF09274.10 EHT97612.1 - 2.1e-47 159.1 1.7 2.3e-47 159.0 1.7 1.0 1 0 0 1 1 1 1 ParG ParD PF09386.10 EHT97612.1 - 0.0043 17.4 0.0 0.0064 16.8 0.0 1.4 1 0 0 1 1 1 1 Antitoxin ParD Resolvase PF00239.21 EHT97614.1 - 3.2e-29 101.9 1.4 5.7e-29 101.1 1.4 1.4 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_7 PF02796.15 EHT97614.1 - 0.00062 19.8 1.4 0.033 14.2 0.0 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_17 PF12728.7 EHT97614.1 - 0.0017 18.5 0.0 0.36 11.0 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 EHT97614.1 - 0.0023 17.7 0.0 0.0059 16.4 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain Trp_repressor PF01371.19 EHT97614.1 - 0.012 15.7 0.1 0.046 13.8 0.1 2.0 1 0 0 1 1 1 0 Trp repressor protein HTH_38 PF13936.6 EHT97614.1 - 0.032 14.0 0.1 0.1 12.4 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain Peptidase_M32 PF02074.15 EHT97614.1 - 0.036 12.9 0.3 0.063 12.0 0.3 1.5 1 1 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase Shal-type PF11601.8 EHT97614.1 - 0.064 12.8 0.2 0.13 11.8 0.2 1.6 1 0 0 1 1 1 0 Shal-type voltage-gated potassium channels, N-terminal RuvB_N PF05496.12 EHT97614.1 - 0.073 12.8 0.2 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Histone_HNS PF00816.21 EHT97615.1 - 1.1e-17 64.7 2.3 1.4e-17 64.3 2.3 1.2 1 0 0 1 1 1 1 H-NS histone family MRP-S26 PF14943.6 EHT97615.1 - 0.082 12.8 6.4 0.13 12.2 6.4 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 KIP1 PF07765.12 EHT97615.1 - 0.11 12.6 1.0 0.2 11.8 1.0 1.3 1 0 0 1 1 1 0 KIP1-like protein UBA_e1_thiolCys PF10585.9 EHT97615.1 - 1 9.2 3.6 6.2 6.7 3.5 1.9 1 1 0 1 1 1 0 Ubiquitin-activating enzyme active site DUF3886 PF13025.6 EHT97615.1 - 3 8.1 13.1 6.4 7.0 13.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Xan_ur_permease PF00860.20 EHT97616.1 - 0.34 9.6 0.0 0.4 9.3 0.0 1.0 1 0 0 1 1 1 0 Permease family DDE_Tnp_1 PF01609.21 EHT97617.1 - 5.5e-20 71.9 0.0 1e-19 71.0 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DnaJ PF00226.31 EHT97618.1 - 9.5e-10 38.5 0.1 2.9e-09 36.9 0.1 1.8 2 0 0 2 2 2 1 DnaJ domain DUF4974 PF16344.5 EHT97618.1 - 0.084 12.9 0.1 0.42 10.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4974) TniQ PF06527.11 EHT97620.1 - 6.9e-23 81.9 2.0 1.3e-22 81.0 2.0 1.5 1 0 0 1 1 1 1 TniQ MFS_1 PF07690.16 EHT97622.1 - 5.1e-10 38.8 38.4 5.1e-10 38.8 38.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MobC PF05713.11 EHT97623.1 - 1.7e-14 54.0 0.9 2.3e-14 53.6 0.9 1.2 1 0 0 1 1 1 1 Bacterial mobilisation protein (MobC) TrbH PF07283.11 EHT97624.1 - 2e-56 189.3 0.5 2.6e-56 188.9 0.5 1.1 1 0 0 1 1 1 1 Conjugal transfer protein TrbH CagX PF03524.15 EHT97625.1 - 3e-59 200.3 0.0 3.9e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 Conjugal transfer protein VirB8 PF04335.13 EHT97626.1 - 3.7e-62 209.9 1.0 4.3e-62 209.7 1.0 1.0 1 0 0 1 1 1 1 VirB8 protein CagE_TrbE_VirB PF03135.14 EHT97627.1 - 1e-64 218.4 0.0 1.6e-64 217.8 0.0 1.3 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system AAA_10 PF12846.7 EHT97627.1 - 0.00025 20.1 0.0 0.01 14.8 0.0 2.2 1 1 0 1 1 1 1 AAA-like domain ABC_tran PF00005.27 EHT97627.1 - 0.00062 20.3 0.0 0.02 15.4 0.0 2.8 3 0 0 3 3 3 1 ABC transporter AAA_22 PF13401.6 EHT97627.1 - 0.0015 18.8 0.1 1.9 8.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain RelE PF06296.12 EHT97628.1 - 4.5e-05 23.5 0.1 4.6e-05 23.5 0.1 1.0 1 0 0 1 1 1 1 RelE toxin of RelE / RelB toxin-antitoxin system HTH_3 PF01381.22 EHT97629.1 - 3.8e-08 33.3 0.1 6.6e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EHT97629.1 - 1e-05 25.7 0.1 2.5e-05 24.5 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain MqsA_antitoxin PF15731.5 EHT97629.1 - 5.7e-05 23.2 0.0 6.6e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Antitoxin component of bacterial toxin-antitoxin system, MqsA HTH_19 PF12844.7 EHT97629.1 - 0.00025 21.0 0.2 0.00048 20.1 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 EHT97629.1 - 0.012 15.4 0.5 0.07 13.0 0.1 2.0 1 1 1 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Phage_CI_repr PF07022.13 EHT97629.1 - 0.17 12.0 0.1 0.34 11.0 0.0 1.6 2 0 0 2 2 2 0 Bacteriophage CI repressor helix-turn-helix domain Resolvase PF00239.21 EHT97631.1 - 1.2e-26 93.6 0.6 2.5e-26 92.5 0.6 1.6 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_23 PF13384.6 EHT97631.1 - 0.0045 16.7 0.1 0.012 15.4 0.1 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.15 EHT97631.1 - 0.0067 16.5 0.1 0.019 15.0 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_36 PF13730.6 EHT97631.1 - 0.16 12.0 0.2 0.44 10.5 0.2 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_38 PF13936.6 EHT97631.1 - 1.7 8.5 4.5 0.25 11.1 0.3 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_IS1 PF12759.7 EHT97632.1 - 2.6e-18 65.3 1.0 2.8e-18 65.2 1.0 1.0 1 0 0 1 1 1 1 InsA C-terminal domain HTH_Tnp_ISL3 PF13542.6 EHT97632.1 - 0.035 13.5 0.0 0.035 13.5 0.0 1.0 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 EHT97632.1 - 0.11 12.3 0.0 0.11 12.3 0.0 1.0 1 0 0 1 1 1 0 Homeodomain-like domain DDE_Tnp_IS1 PF03400.13 EHT97633.1 - 6.1e-36 123.6 0.7 6.6e-36 123.5 0.7 1.0 1 0 0 1 1 1 1 IS1 transposase Y2_Tnp PF04986.13 EHT97634.1 - 2.6e-49 167.7 1.0 3.4e-49 167.4 1.0 1.1 1 0 0 1 1 1 1 Putative transposase Zn_Tnp_IS91 PF14319.6 EHT97634.1 - 1.1e-13 51.0 1.9 2.6e-13 49.8 1.9 1.6 1 0 0 1 1 1 1 Transposase zinc-binding domain HTH_28 PF13518.6 EHT97635.1 - 0.017 15.2 2.6 0.036 14.2 2.6 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain DDE_Tnp_IS66 PF03050.14 EHT97635.1 - 0.032 13.7 0.1 0.037 13.5 0.1 1.0 1 0 0 1 1 1 0 Transposase IS66 family HTH_23 PF13384.6 EHT97635.1 - 0.074 12.9 4.1 0.28 11.0 3.6 2.2 1 1 0 1 1 1 0 Homeodomain-like domain Tox-PLDMTX PF15645.6 EHT97636.1 - 2.5e-10 40.8 0.1 8.6e-10 39.0 0.1 1.9 1 0 0 1 1 1 1 Dermonecrotoxin of the Papain-like fold DUF1805 PF08827.11 EHT97636.1 - 2.6 8.4 4.6 4.6 7.7 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1805) DDE_Tnp_IS1 PF03400.13 EHT97637.1 - 6.1e-36 123.6 0.7 6.6e-36 123.5 0.7 1.0 1 0 0 1 1 1 1 IS1 transposase HTH_Tnp_IS1 PF12759.7 EHT97638.1 - 2.6e-18 65.3 1.0 2.8e-18 65.2 1.0 1.0 1 0 0 1 1 1 1 InsA C-terminal domain HTH_Tnp_ISL3 PF13542.6 EHT97638.1 - 0.035 13.5 0.0 0.035 13.5 0.0 1.0 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 EHT97638.1 - 0.11 12.3 0.0 0.11 12.3 0.0 1.0 1 0 0 1 1 1 0 Homeodomain-like domain Mrr_cat PF04471.12 EHT97639.1 - 1.6e-07 31.3 0.0 2.8e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease Bac_RepA_C PF18008.1 EHT97640.1 - 0.071 13.5 0.1 0.079 13.3 0.1 1.1 1 0 0 1 1 1 0 Replication initiator protein A C-terminal domain EF-hand_12 PF17901.1 EHT97640.1 - 0.084 13.3 0.0 0.085 13.3 0.0 1.1 1 0 0 1 1 1 0 EF-hand fold domain MipZ PF09140.11 EHT97641.1 - 0.00031 20.1 1.8 0.0012 18.2 0.4 2.0 1 1 0 2 2 2 2 ATPase MipZ IncFII_repA PF02387.15 EHT97643.1 - 8.8e-26 90.8 0.1 1.2e-25 90.3 0.1 1.3 1 0 0 1 1 1 1 IncFII RepA protein family RepB-RCR_reg PF10723.9 EHT97644.1 - 5.3e-14 51.9 0.0 5.8e-14 51.8 0.0 1.0 1 0 0 1 1 1 1 Replication regulatory protein RepB RHH_5 PF07878.11 EHT97644.1 - 1.5e-06 27.9 0.1 1.9e-06 27.6 0.1 1.1 1 0 0 1 1 1 1 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 RHH_1 PF01402.21 EHT97644.1 - 6.6e-05 22.7 0.0 8.3e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family CUTL PF16557.5 EHT97644.1 - 0.11 12.7 0.0 0.12 12.6 0.0 1.0 1 0 0 1 1 1 0 CUT1-like DNA-binding domain of SATB PLDc_2 PF13091.6 EHT97645.1 - 2.3e-25 89.0 0.2 2.7e-25 88.8 0.2 1.0 1 0 0 1 1 1 1 PLD-like domain FAM83 PF07894.12 EHT97645.1 - 3.3e-07 30.1 0.3 3.2e-05 23.6 0.3 2.0 1 1 0 1 1 1 1 FAM83 A-H PP_kinase_C PF13090.6 EHT97645.1 - 0.031 13.7 0.1 0.066 12.7 0.0 1.5 2 0 0 2 2 2 0 Polyphosphate kinase C-terminal domain 2 DUF1189 PF06691.11 EHT97645.1 - 0.097 12.2 0.2 5.7 6.4 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1189) DUF2913 PF11140.8 EHT97646.1 - 5.4e-14 52.4 0.0 6.4e-14 52.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2913) TraI PF07057.11 EHT97647.1 - 7.4e-06 26.1 0.0 4e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 DNA helicase TraI AAA_30 PF13604.6 EHT97648.1 - 2.6e-37 128.4 3.6 2.6e-37 128.4 3.6 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EHT97648.1 - 2.3e-10 41.0 0.4 5.3e-10 39.8 0.1 1.7 2 0 0 2 2 2 1 AAA domain TraI PF07057.11 EHT97648.1 - 7.2e-06 26.1 0.1 2.1e-05 24.6 0.1 1.8 1 0 0 1 1 1 1 DNA helicase TraI UvrD_C_2 PF13538.6 EHT97648.1 - 0.0015 18.3 0.2 0.003 17.3 0.2 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_11 PF13086.6 EHT97648.1 - 0.022 14.6 0.0 0.66 9.7 0.0 2.5 2 1 0 3 3 3 0 AAA domain Viral_helicase1 PF01443.18 EHT97648.1 - 0.09 12.5 0.0 0.5 10.1 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Lipocalin_8 PF16585.5 EHT97648.1 - 0.1 13.0 0.1 1.6 9.2 0.0 2.3 2 0 0 2 2 2 0 Lipocalin-like domain Helicase_RecD PF05127.14 EHT97648.1 - 0.12 12.2 0.2 25 4.7 0.0 2.6 1 1 0 2 2 2 0 Helicase DDE_Tnp_IS66 PF03050.14 EHT97649.1 - 2.7e-97 325.7 4.0 1.2e-96 323.5 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT97649.1 - 3.3e-16 59.2 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT97649.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT97649.1 - 8.7e-11 42.4 9.0 1.9e-10 41.4 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Phage_HK97_TLTM PF06120.11 EHT97649.1 - 0.011 15.0 0.8 0.021 14.0 0.8 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHT97649.1 - 0.02 15.2 4.2 0.084 13.2 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain UME PF08064.13 EHT97649.1 - 0.032 14.1 0.3 20 5.1 0.0 3.1 2 1 1 3 3 3 0 UME (NUC010) domain Exonuc_VII_L PF02601.15 EHT97649.1 - 0.039 13.5 2.7 0.04 13.5 1.0 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Troponin PF00992.20 EHT97649.1 - 0.044 14.1 2.8 0.078 13.3 2.8 1.3 1 0 0 1 1 1 0 Troponin FUSC PF04632.12 EHT97649.1 - 0.048 12.2 7.4 0.077 11.5 7.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tho2 PF11262.8 EHT97649.1 - 0.049 12.8 0.6 0.081 12.1 0.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FAM184 PF15665.5 EHT97649.1 - 0.052 13.3 8.0 0.082 12.7 8.0 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B HalX PF08663.10 EHT97649.1 - 0.13 12.6 2.4 0.34 11.3 2.4 1.7 1 0 0 1 1 1 0 HalX domain LXG PF04740.12 EHT97649.1 - 0.14 11.8 2.8 0.35 10.5 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHT97649.1 - 0.19 11.5 11.1 0.31 10.8 11.1 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DHR10 PF18595.1 EHT97649.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Zn-ribbon_8 PF09723.10 EHT97649.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF1192 PF06698.11 EHT97649.1 - 0.54 10.4 5.3 3.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHT97649.1 - 0.82 8.9 3.0 1.2 8.3 3.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHT97649.1 - 2 8.0 8.1 4.3 6.8 8.1 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHT97649.1 - 4.2 7.7 8.6 8.7 6.7 8.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CREPT PF16566.5 EHT97649.1 - 5.9 7.1 8.7 2.7 8.1 5.6 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour SlyX PF04102.12 EHT97649.1 - 9.7 6.9 9.0 18 6.1 2.3 3.0 1 1 1 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHT97650.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHT97651.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT97651.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT97651.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT97651.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix Ldt_C PF17969.1 EHT97652.1 - 1.7e-25 89.5 0.3 4.2e-25 88.3 0.3 1.7 1 0 0 1 1 1 1 L,D-transpeptidase C-terminal domain YkuD PF03734.14 EHT97652.1 - 1e-17 64.9 0.0 1.7e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain LysM PF01476.20 EHT97652.1 - 0.0038 17.3 0.0 0.0076 16.3 0.0 1.5 1 0 0 1 1 1 1 LysM domain CorA PF01544.18 EHT97653.1 - 1e-43 149.8 2.5 1.2e-43 149.5 2.5 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2207 PF09972.9 EHT97653.1 - 0.18 10.5 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) HTH_Tnp_1 PF01527.20 EHT97654.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT97654.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT97654.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT97654.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHT97655.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHT97656.1 - 3.4e-98 328.6 2.9 1.9e-97 326.1 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT97656.1 - 3.1e-16 59.3 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT97656.1 - 1.4e-14 54.2 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT97656.1 - 8.8e-11 42.4 8.7 1.9e-10 41.4 8.7 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHT97656.1 - 0.023 14.5 5.9 0.036 13.8 5.9 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Phage_HK97_TLTM PF06120.11 EHT97656.1 - 0.028 13.6 1.5 0.054 12.7 1.5 1.4 1 0 0 1 1 1 0 Tail length tape measure protein FUSC PF04632.12 EHT97656.1 - 0.03 12.9 6.3 0.048 12.2 6.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Csm1_N PF18504.1 EHT97656.1 - 0.032 14.5 4.4 0.12 12.8 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Tho2 PF11262.8 EHT97656.1 - 0.044 13.0 0.5 0.074 12.2 0.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Exonuc_VII_L PF02601.15 EHT97656.1 - 0.096 12.2 2.0 0.12 11.9 0.7 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit ERM PF00769.19 EHT97656.1 - 0.14 11.9 9.9 0.23 11.2 9.9 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family UME PF08064.13 EHT97656.1 - 0.17 11.8 0.5 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain HalX PF08663.10 EHT97656.1 - 0.19 12.1 3.0 0.49 10.7 3.0 1.7 1 0 0 1 1 1 0 HalX domain LXG PF04740.12 EHT97656.1 - 0.29 10.8 2.3 1.1 9.0 0.3 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily Zn-ribbon_8 PF09723.10 EHT97656.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DHR10 PF18595.1 EHT97656.1 - 0.52 10.4 10.4 0.91 9.6 10.4 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF1192 PF06698.11 EHT97656.1 - 1 9.4 6.1 4 7.6 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) HAUS-augmin3 PF14932.6 EHT97656.1 - 4.2 6.9 7.3 9.3 5.7 7.3 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 SlyX PF04102.12 EHT97656.1 - 6.1 7.5 8.3 8.1 7.1 1.0 3.0 1 1 0 2 2 2 0 SlyX Holin_2-3 PF13272.6 EHT97658.1 - 5e-39 132.8 1.0 5.6e-39 132.7 1.0 1.0 1 0 0 1 1 1 1 Putative 2/3 transmembrane domain holin ATPase_gene1 PF09527.10 EHT97658.1 - 0.012 15.7 0.4 0.74 10.0 0.0 2.5 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Transport_MerF PF11431.8 EHT97658.1 - 0.16 11.9 0.5 0.16 11.9 0.5 2.4 2 0 0 2 2 2 0 Membrane transport protein MerF SLT PF01464.20 EHT97659.1 - 6.9e-14 51.5 0.0 1e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase SLT domain OmpH PF03938.14 EHT97660.1 - 0.0011 19.3 1.0 0.0017 18.7 1.0 1.3 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Filament PF00038.21 EHT97660.1 - 0.0055 16.3 1.6 0.011 15.4 0.2 1.9 1 1 1 2 2 2 1 Intermediate filament protein SHE3 PF17078.5 EHT97660.1 - 0.019 14.7 0.6 0.56 9.9 0.2 2.2 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 YlqD PF11068.8 EHT97660.1 - 0.031 14.7 2.3 0.031 14.7 2.3 1.7 2 0 0 2 2 2 0 YlqD protein DUF2353 PF09789.9 EHT97660.1 - 0.042 13.2 1.7 0.1 11.9 0.6 1.8 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) HTH_25 PF13413.6 EHT97660.1 - 0.074 12.9 0.0 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain APG6_N PF17675.1 EHT97660.1 - 0.084 13.4 6.3 0.05 14.1 3.7 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region Uso1_p115_C PF04871.13 EHT97660.1 - 0.11 12.9 4.9 0.18 12.1 4.9 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Filo_VP35 PF02097.15 EHT97660.1 - 0.13 11.3 0.1 0.22 10.5 0.0 1.5 1 1 0 1 1 1 0 Filoviridae VP35 DUF4407 PF14362.6 EHT97660.1 - 0.35 10.2 6.5 1 8.7 6.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) JAKMIP_CC3 PF16034.5 EHT97660.1 - 0.64 9.9 6.8 0.59 10.1 4.6 1.8 1 1 0 2 2 2 0 JAKMIP CC3 domain Phage_GPO PF05929.11 EHT97661.1 - 0.03 14.0 0.0 0.034 13.8 0.0 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase SLATT_1 PF18181.1 EHT97661.1 - 0.048 13.6 0.1 0.068 13.1 0.1 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 DUF3486 PF11985.8 EHT97663.1 - 3e-53 180.9 10.8 3.3e-53 180.8 10.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3486) HTH_32 PF13565.6 EHT97663.1 - 0.004 17.7 1.9 0.0095 16.5 0.2 2.3 2 1 0 2 2 2 1 Homeodomain-like domain HTH_12 PF08461.10 EHT97663.1 - 0.03 14.3 1.4 0.081 12.9 1.1 1.9 1 1 0 1 1 1 0 Ribonuclease R winged-helix domain PDEase_I_N PF08499.12 EHT97663.1 - 0.077 12.9 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal Terminase_6 PF03237.15 EHT97664.1 - 0.0067 16.1 0.0 0.011 15.4 0.0 1.5 1 1 0 1 1 1 1 Terminase-like family DUF935 PF06074.12 EHT97665.1 - 2.3e-109 366.5 0.0 2.8e-109 366.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF935) DUF935 PF06074.12 EHT97666.1 - 3.2e-14 52.6 0.0 3.2e-14 52.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF935) Phage_Mu_F PF04233.14 EHT97667.1 - 1.8e-29 102.7 0.0 3.1e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 Phage Mu protein F like protein EPF PF17181.4 EHT97667.1 - 0.17 11.9 0.2 0.31 11.1 0.2 1.3 1 0 0 1 1 1 0 Epidermal patterning factor proteins HEPN_STY4199 PF18729.1 EHT97667.1 - 0.22 10.7 0.2 0.33 10.1 0.2 1.2 1 0 0 1 1 1 0 STY4199-like HEPN Phage_tail_S PF05069.13 EHT97668.1 - 8.2e-22 77.6 0.0 9.2e-22 77.5 0.0 1.0 1 0 0 1 1 1 1 Phage virion morphogenesis family TetR_C_30 PF17939.1 EHT97668.1 - 0.051 13.8 0.0 9.1 6.6 0.0 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain IMPa_N_2 PF18650.1 EHT97668.1 - 0.15 11.3 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Immunomodulating metalloprotease N-terminal domain UPF0242 PF06785.11 EHT97669.1 - 0.081 13.0 2.4 0.14 12.3 2.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Phage_cap_E PF03864.15 EHT97670.1 - 0.0015 17.8 0.0 0.0022 17.2 0.0 1.3 1 0 0 1 1 1 1 Phage major capsid protein E DUF2190 PF09956.9 EHT97671.1 - 4.5e-18 65.6 11.6 5.6e-18 65.3 11.6 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2190) AbiEi_4 PF13338.6 EHT97671.1 - 0.04 14.1 0.4 0.11 12.7 0.4 1.8 1 1 1 2 2 2 0 Transcriptional regulator, AbiEi antitoxin DUF1320 PF07030.12 EHT97672.1 - 2.6e-38 131.0 0.2 2.9e-38 130.8 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1320) Gp37 PF09646.10 EHT97673.1 - 2.3e-62 209.1 0.0 2.6e-62 208.9 0.0 1.0 1 0 0 1 1 1 1 Gp37 protein Phage_sheath_1 PF04984.14 EHT97675.1 - 5.7e-32 110.9 0.0 1.4e-31 109.7 0.0 1.7 1 0 0 1 1 1 1 Phage tail sheath protein subtilisin-like domain Phage_sheath_1C PF17482.2 EHT97675.1 - 5e-14 52.2 0.0 1.2e-13 50.9 0.0 1.7 2 0 0 2 2 2 1 Phage tail sheath C-terminal domain Phage_tube PF04985.14 EHT97676.1 - 1.6e-54 184.1 0.0 1.8e-54 183.9 0.0 1.0 1 0 0 1 1 1 1 Phage tail tube protein FII Phage_gp49_66 PF13876.6 EHT97677.1 - 3.4e-13 49.7 0.0 4.2e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Phage protein (N4 Gp49/phage Sf6 gene 66) family DDE_Tnp_1 PF01609.21 EHT97679.1 - 2.8e-20 72.9 0.0 6.1e-20 71.8 0.0 1.5 1 1 0 1 1 1 1 Transposase DDE domain Phage_TAC_7 PF10109.9 EHT97681.1 - 1.1e-20 73.5 0.1 1.4e-20 73.2 0.1 1.1 1 0 0 1 1 1 1 Phage tail assembly chaperone proteins, E, or 41 or 14 DIMCO_N PF16844.5 EHT97681.1 - 0.1 13.0 0.1 0.17 12.3 0.1 1.4 1 1 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor, N-terminal Phage_P2_GpE PF06528.12 EHT97682.1 - 2.8e-05 23.6 0.3 3.2e-05 23.4 0.3 1.1 1 0 0 1 1 1 1 Phage P2 GpE Head-tail_con PF12236.8 EHT97682.1 - 0.0013 17.3 0.4 0.0014 17.1 0.4 1.0 1 0 0 1 1 1 1 Bacteriophage head to tail connecting protein PhageMin_Tail PF10145.9 EHT97683.1 - 2.7e-13 50.2 28.2 2.7e-13 50.2 28.2 3.2 3 1 0 3 3 3 1 Phage-related minor tail protein Phage_P2_GpU PF06995.11 EHT97684.1 - 1.4e-32 111.8 0.0 2.1e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Phage P2 GpU Phage_tail_X PF05489.12 EHT97685.1 - 5.2e-17 61.3 0.0 6.2e-17 61.0 0.0 1.1 1 0 0 1 1 1 1 Phage Tail Protein X Phage_GPD PF05954.11 EHT97686.1 - 2.3e-12 46.8 0.1 3.5e-12 46.2 0.1 1.2 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) Phage_base_V PF04717.12 EHT97687.1 - 5.9e-19 68.0 0.0 8.5e-19 67.5 0.0 1.2 1 0 0 1 1 1 1 Type VI secretion system, phage-baseplate injector DUF4998 PF16389.5 EHT97687.1 - 0.034 13.8 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function GPW_gp25 PF04965.14 EHT97688.1 - 5.3e-10 38.9 0.0 6.3e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Gene 25-like lysozyme DUF2634 PF10934.8 EHT97688.1 - 0.0061 16.6 0.0 0.0079 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2634) Baseplate_J PF04865.14 EHT97689.1 - 2.5e-73 246.4 0.5 3.8e-73 245.8 0.5 1.3 1 0 0 1 1 1 1 Baseplate J-like protein Tail_P2_I PF09684.10 EHT97690.1 - 7.1e-32 110.2 0.0 8.5e-32 109.9 0.0 1.1 1 0 0 1 1 1 1 Phage tail protein (Tail_P2_I) MarR_2 PF12802.7 EHT97691.1 - 0.024 14.5 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 MarR family Caudo_TAP PF02413.17 EHT97692.1 - 1.3e-12 48.0 0.1 1.4e-12 47.9 0.1 1.0 1 0 0 1 1 1 1 Caudovirales tail fibre assembly protein, lambda gpK DUF469 PF04320.14 EHT97692.1 - 0.011 16.5 0.1 0.012 16.5 0.1 1.0 1 0 0 1 1 1 0 Protein with unknown function (DUF469) Caudo_TAP PF02413.17 EHT97693.1 - 2.5e-24 85.9 0.1 2.9e-24 85.7 0.1 1.0 1 0 0 1 1 1 1 Caudovirales tail fibre assembly protein, lambda gpK Resolvase PF00239.21 EHT97694.1 - 6.8e-45 152.8 0.2 1e-44 152.2 0.2 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_7 PF02796.15 EHT97694.1 - 3.4e-13 49.4 0.1 1.5e-12 47.4 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 EHT97694.1 - 0.0071 16.1 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 EHT97694.1 - 0.014 16.0 0.2 0.026 15.1 0.2 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_38 PF13936.6 EHT97694.1 - 0.018 14.8 0.1 0.083 12.7 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_4 PF13613.6 EHT97694.1 - 0.022 14.5 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_29 PF13551.6 EHT97694.1 - 0.067 13.2 1.8 0.4 10.7 0.1 2.4 1 1 1 2 2 2 0 Winged helix-turn helix HTH_psq PF05225.16 EHT97694.1 - 0.069 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 helix-turn-helix, Psq domain adh_short PF00106.25 EHT97695.1 - 6.9e-23 81.1 0.0 8.2e-23 80.9 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EHT97695.1 - 1.2e-19 70.8 0.1 1.4e-19 70.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EHT97695.1 - 4.1e-07 30.1 0.0 4.8e-07 29.9 0.0 1.0 1 0 0 1 1 1 1 KR domain LytR_C PF13399.6 EHT97695.1 - 0.018 16.0 0.1 0.025 15.6 0.1 1.4 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator Epimerase PF01370.21 EHT97695.1 - 0.051 13.0 0.0 0.056 12.9 0.0 1.0 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyco_trans_4_2 PF13477.6 EHT97695.1 - 0.08 13.0 0.0 0.095 12.7 0.0 1.3 1 1 0 1 1 1 0 Glycosyl transferase 4-like DUF1493 PF07377.12 EHT97696.1 - 1.6e-22 80.0 1.8 1.9e-22 79.8 1.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) Telomere_res PF16684.5 EHT97698.1 - 2.6e-17 63.2 0.0 3.9e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Telomere resolvase Toprim_3 PF13362.6 EHT97701.1 - 1.1e-05 25.7 0.2 0.00012 22.4 0.0 2.9 2 0 0 2 2 2 1 Toprim domain Herpes_ori_bp PF02399.15 EHT97701.1 - 1.5e-05 23.3 0.0 5.2e-05 21.5 0.0 1.7 1 1 0 1 1 1 1 Origin of replication binding protein PRC PF05239.16 EHT97701.1 - 0.17 12.0 0.0 0.74 9.9 0.1 2.0 2 0 0 2 2 2 0 PRC-barrel domain HTH_3 PF01381.22 EHT97702.1 - 1.1e-07 31.8 0.1 2.2e-07 30.8 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix Phage_CI_repr PF07022.13 EHT97702.1 - 6.6e-06 26.1 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Bacteriophage CI repressor helix-turn-helix domain HTH_31 PF13560.6 EHT97702.1 - 0.00015 22.1 0.1 0.00026 21.3 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 EHT97702.1 - 0.00024 21.0 0.0 0.00062 19.7 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain P22_Cro PF14549.6 EHT97703.1 - 4.5e-20 71.2 0.1 5.4e-20 71.0 0.1 1.1 1 0 0 1 1 1 1 DNA-binding transcriptional regulator Cro HTH_1 PF00126.27 EHT97703.1 - 0.00086 19.2 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family YdaS_antitoxin PF15943.5 EHT97703.1 - 0.0016 18.2 0.0 0.002 17.9 0.0 1.1 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 EHT97703.1 - 0.0016 18.1 0.2 0.0044 16.8 0.0 1.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 EHT97703.1 - 0.0029 17.6 0.6 0.02 14.9 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_30 PF13556.6 EHT97703.1 - 0.0089 15.8 0.1 0.015 15.1 0.1 1.3 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain NUMOD1 PF07453.13 EHT97703.1 - 0.0091 16.2 0.1 0.014 15.6 0.1 1.3 1 0 0 1 1 1 1 NUMOD1 domain HTH_28 PF13518.6 EHT97703.1 - 0.012 15.7 0.1 0.012 15.7 0.1 1.8 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_22 PF13309.6 EHT97703.1 - 0.017 15.2 0.1 0.028 14.5 0.1 1.4 1 0 0 1 1 1 0 HTH domain HTH_8 PF02954.19 EHT97703.1 - 0.019 14.8 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family Phage_antiter_Q PF06323.11 EHT97704.1 - 1.4e-49 168.6 0.0 1.9e-49 168.2 0.0 1.0 1 0 0 1 1 1 1 Phage antitermination protein Q Nucleic_acid_bd PF13820.6 EHT97704.1 - 0.12 12.2 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Putative nucleic acid-binding region RdgC PF04381.12 EHT97706.1 - 0.0058 15.9 0.0 0.007 15.7 0.0 1.2 1 0 0 1 1 1 1 Putative exonuclease, RdgC HTH_3 PF01381.22 EHT97708.1 - 3.7e-09 36.5 0.0 6.3e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EHT97708.1 - 3.5e-08 33.7 0.0 5.8e-08 33.0 0.0 1.3 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 EHT97708.1 - 1.9e-07 31.0 0.1 3.9e-07 30.0 0.0 1.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_37 PF13744.6 EHT97708.1 - 6.4e-07 29.2 0.0 6.8e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 EHT97708.1 - 3.2e-05 24.3 0.0 5.7e-05 23.5 0.0 1.4 2 0 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 EHT97708.1 - 0.00015 21.3 0.3 0.0012 18.4 0.1 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_25 PF13413.6 EHT97708.1 - 0.00047 20.0 0.5 0.0012 18.7 0.5 1.8 1 1 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 EHT97708.1 - 0.00087 19.1 0.1 0.0018 18.1 0.1 1.5 2 0 0 2 2 2 1 MarR family Fe_dep_repress PF01325.19 EHT97708.1 - 0.0017 18.5 0.2 0.0041 17.3 0.0 1.7 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain MarR PF01047.22 EHT97708.1 - 0.0029 17.5 0.2 0.0064 16.4 0.1 1.5 2 0 0 2 2 2 1 MarR family HTH_AsnC-type PF13404.6 EHT97708.1 - 0.032 14.1 0.1 0.058 13.2 0.1 1.4 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_23 PF13384.6 EHT97708.1 - 0.072 12.9 0.0 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain CENP-B_N PF04218.13 EHT97708.1 - 0.093 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain SIS PF01380.22 EHT97708.1 - 0.096 12.5 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 SIS domain Gp49 PF05973.14 EHT97709.1 - 2.3e-25 88.5 0.0 2.6e-25 88.4 0.0 1.0 1 0 0 1 1 1 1 Phage derived protein Gp49-like (DUF891) MbeD_MobD PF04899.12 EHT97711.1 - 0.0018 18.4 1.4 0.065 13.4 0.1 2.1 1 1 1 2 2 2 1 MbeD/MobD like Apolipoprotein PF01442.18 EHT97711.1 - 0.014 15.3 0.2 0.017 15.0 0.2 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain MscS_porin PF12795.7 EHT97711.1 - 0.016 14.7 2.1 0.02 14.5 2.1 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain V-SNARE PF05008.15 EHT97711.1 - 0.021 15.2 0.2 0.024 15.0 0.2 1.1 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus SKA2 PF16740.5 EHT97711.1 - 0.041 13.7 0.1 0.05 13.4 0.1 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 DUF4200 PF13863.6 EHT97711.1 - 0.081 13.3 0.5 6.2 7.2 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) FlxA PF14282.6 EHT97711.1 - 0.17 11.9 3.5 0.26 11.3 3.5 1.4 1 1 0 1 1 1 0 FlxA-like protein Hexapep_2 PF14602.6 EHT97712.1 - 7.7e-07 28.8 14.6 1.2e-05 25.0 6.6 3.4 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 EHT97712.1 - 2e-06 27.3 16.3 0.031 14.0 0.6 4.1 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 EHT97712.1 - 0.14 11.0 0.3 0.26 10.2 0.3 1.3 1 1 0 1 1 1 0 L-fucokinase DUF905 PF06006.12 EHT97713.1 - 7.9e-08 32.2 0.3 2.4e-07 30.6 0.1 1.9 2 1 0 2 2 2 1 Bacterial protein of unknown function (DUF905) UN_NPL4 PF11543.8 EHT97713.1 - 0.044 14.3 0.1 0.15 12.5 0.1 1.8 1 1 1 2 2 2 0 Nuclear pore localisation protein NPL4 DUF1571 PF07608.11 EHT97714.1 - 0.034 13.6 0.0 0.036 13.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1571) N6_N4_Mtase PF01555.18 EHT97716.1 - 2.3e-31 109.3 0.0 1.5e-30 106.7 0.0 1.9 1 1 0 1 1 1 1 DNA methylase HALZ PF02183.18 EHT97716.1 - 0.00097 19.3 7.3 0.0011 19.1 4.4 2.6 2 1 0 2 2 2 1 Homeobox associated leucine zipper HOOK PF05622.12 EHT97716.1 - 0.0024 16.1 0.0 0.0035 15.6 0.0 1.2 1 0 0 1 1 1 1 HOOK protein Bap31_Bap29_C PF18035.1 EHT97716.1 - 0.013 15.5 6.2 0.045 13.8 6.2 1.9 1 1 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain DivIC PF04977.15 EHT97716.1 - 0.15 11.8 2.0 1.5 8.6 0.0 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF4407 PF14362.6 EHT97716.1 - 0.46 9.8 2.2 0.76 9.1 0.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Phage_holin_2_1 PF04971.12 EHT97717.1 - 1.3e-15 57.1 2.5 1.4e-15 57.0 2.5 1.1 1 0 0 1 1 1 1 Bacteriophage P21 holin S Phage_lysozyme PF00959.19 EHT97718.1 - 2.1e-19 70.0 0.0 2.7e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Phage lysozyme Pox_ATPase-GT PF10640.9 EHT97718.1 - 0.24 10.2 0.0 0.3 9.9 0.0 1.1 1 0 0 1 1 1 0 mRNA capping enzyme N-terminal, ATPase and guanylyltransferase SurA_N_2 PF13623.6 EHT97719.1 - 0.034 14.0 0.1 0.05 13.5 0.1 1.2 1 0 0 1 1 1 0 SurA N-terminal domain DUF2570 PF10828.8 EHT97719.1 - 0.069 13.0 0.5 0.16 11.8 0.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) DLIC PF05783.11 EHT97720.1 - 0.71 8.6 2.8 0.83 8.4 2.8 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) MmcB-like PF06319.12 EHT97730.1 - 0.15 11.7 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 DNA repair protein MmcB-like Terminase_GpA PF05876.12 EHT97732.1 - 1.3e-164 548.8 0.0 1.6e-164 548.5 0.0 1.0 1 0 0 1 1 1 1 Phage terminase large subunit (GpA) Lar_restr_allev PF14354.6 EHT97732.1 - 0.16 12.4 0.1 0.37 11.2 0.1 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar gpW PF02831.15 EHT97733.1 - 3.3e-14 52.5 0.2 3.7e-14 52.4 0.2 1.1 1 0 0 1 1 1 1 gpW Phage_portal_2 PF05136.13 EHT97734.1 - 1.4e-101 340.3 3.8 1.6e-101 340.0 3.8 1.1 1 0 0 1 1 1 1 Phage portal protein, lambda family Peptidase_S49 PF01343.18 EHT97735.1 - 1.4e-27 96.6 0.1 2e-27 96.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase family S49 CLP_protease PF00574.23 EHT97735.1 - 0.00013 21.9 0.0 0.01 15.7 0.0 2.1 2 0 0 2 2 2 2 Clp protease Nop14 PF04147.12 EHT97736.1 - 2.4e-05 22.8 13.8 2.7e-05 22.6 13.8 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 EHT97736.1 - 0.0013 18.3 18.8 0.0014 18.1 18.8 1.1 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 EHT97736.1 - 0.0021 17.5 16.9 0.0022 17.4 16.9 1.2 1 0 0 1 1 1 1 BUD22 TIMELESS_C PF05029.13 EHT97736.1 - 0.71 8.9 18.0 0.82 8.7 18.0 1.1 1 0 0 1 1 1 0 Timeless protein C terminal region DNA_gyraseA_C PF03989.13 EHT97736.1 - 0.77 9.3 2.3 10 5.7 0.2 2.5 2 0 0 2 2 2 0 DNA gyrase C-terminal domain, beta-propeller Presenilin PF01080.17 EHT97736.1 - 3.2 6.4 4.9 3.2 6.4 4.9 1.1 1 0 0 1 1 1 0 Presenilin HDPD PF02924.14 EHT97737.1 - 6.1e-10 39.2 21.2 1.3e-06 28.5 21.2 2.5 1 1 0 1 1 1 1 Bacteriophage lambda head decoration protein D SAP PF02037.27 EHT97737.1 - 0.065 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 SAP domain MG2 PF01835.19 EHT97737.1 - 0.11 13.0 1.4 9 6.8 0.3 2.8 1 1 1 2 2 2 0 MG2 domain Phage_cap_E PF03864.15 EHT97738.1 - 8.9e-66 222.3 0.0 1e-65 222.2 0.0 1.0 1 0 0 1 1 1 1 Phage major capsid protein E DUF348 PF03990.14 EHT97739.1 - 0.015 15.0 1.9 0.035 13.8 0.5 2.3 2 0 0 2 2 2 0 G5-linked-Ubiquitin-like domain HK97-gp10_like PF04883.12 EHT97739.1 - 0.087 13.8 1.5 0.19 12.7 0.2 1.9 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component Ten1_2 PF15490.6 EHT97741.1 - 0.07 12.8 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Telomere-capping, CST complex subunit DUF2635 PF10948.8 EHT97742.1 - 1.6e-19 69.4 0.3 2.2e-19 68.9 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2635) Phage_sheath_1 PF04984.14 EHT97743.1 - 4e-18 65.8 1.6 1.7e-17 63.8 0.0 2.3 2 0 0 2 2 2 1 Phage tail sheath protein subtilisin-like domain Phage_sheath_1C PF17482.2 EHT97743.1 - 2e-11 43.7 0.0 4.1e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Phage tail sheath C-terminal domain Phage_sheath_1N PF17481.2 EHT97743.1 - 0.0076 16.7 4.7 0.07 13.6 4.5 2.8 1 1 1 2 2 2 1 Phage tail sheath protein beta-sandwich domain Tail_tube PF10618.9 EHT97744.1 - 4.1e-40 136.3 2.4 4.5e-40 136.2 2.4 1.0 1 0 0 1 1 1 1 Phage tail tube protein EIIBC-GUT_N PF03612.14 EHT97744.1 - 0.0087 15.8 0.1 0.01 15.6 0.1 1.2 1 0 0 1 1 1 1 Sorbitol phosphotransferase enzyme II N-terminus Phage_TAC_7 PF10109.9 EHT97745.1 - 1e-11 44.8 0.0 9.5e-07 28.9 0.0 2.1 2 0 0 2 2 2 2 Phage tail assembly chaperone proteins, E, or 41 or 14 ubiquitin PF00240.23 EHT97746.1 - 0.12 12.2 0.1 3.9 7.3 0.0 2.7 2 0 0 2 2 2 0 Ubiquitin family COG6 PF06419.11 EHT97746.1 - 0.22 9.7 0.1 0.8 7.8 0.0 1.9 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 DNA_circ_N PF07157.12 EHT97747.1 - 1.2e-33 115.3 0.0 2.6e-33 114.3 0.0 1.6 1 0 0 1 1 1 1 DNA circularisation protein N-terminus HalX PF08663.10 EHT97747.1 - 0.076 13.3 0.5 0.65 10.4 0.1 2.4 2 0 0 2 2 2 0 HalX domain Phage_GPD PF05954.11 EHT97748.1 - 2.3e-13 50.1 0.0 2.8e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) Phage_Mu_Gp45 PF06890.12 EHT97749.1 - 1e-23 83.0 0.1 2.2e-23 81.9 0.0 1.6 2 0 0 2 2 2 1 Bacteriophage Mu Gp45 protein Phage_spike PF18715.1 EHT97749.1 - 0.0056 16.7 2.6 0.011 15.8 0.7 2.4 2 0 0 2 2 2 1 Phage spike trimer GP46 PF07409.12 EHT97750.1 - 3.7e-36 123.4 1.1 4.3e-36 123.2 1.1 1.1 1 0 0 1 1 1 1 Phage protein GP46 SLH PF00395.20 EHT97750.1 - 0.11 12.6 0.3 1.1 9.4 0.1 2.3 2 0 0 2 2 2 0 S-layer homology domain Baseplate_J PF04865.14 EHT97751.1 - 6.8e-75 251.5 10.0 8.3e-75 251.2 10.0 1.1 1 0 0 1 1 1 1 Baseplate J-like protein DUF2313 PF10076.9 EHT97752.1 - 5.5e-34 117.4 0.0 6.2e-34 117.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2313) PknH_C PF14032.6 EHT97752.1 - 0.033 14.0 1.3 0.046 13.6 1.3 1.2 1 0 0 1 1 1 0 PknH-like extracellular domain TetR_C_31 PF17940.1 EHT97753.1 - 0.077 13.2 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Collar PF07484.12 EHT97754.1 - 2e-07 30.9 0.3 5.5e-07 29.5 0.3 1.8 1 0 0 1 1 1 1 Phage Tail Collar Domain Phage_fiber PF03335.13 EHT97754.1 - 0.1 12.8 36.6 0.67 10.3 0.4 6.0 4 1 1 5 5 5 0 Phage tail fibre repeat Caudo_TAP PF02413.17 EHT97755.1 - 1.4e-17 64.0 1.5 1.8e-17 63.7 1.5 1.4 1 1 0 1 1 1 1 Caudovirales tail fibre assembly protein, lambda gpK Phage_tail_APC PF16778.5 EHT97755.1 - 0.00047 20.0 0.2 0.0012 18.7 0.2 1.7 1 0 0 1 1 1 1 Phage tail assembly chaperone protein SoPB_HTH PF18090.1 EHT97756.1 - 7.2e-20 70.9 0.1 1.4e-19 70.0 0.1 1.5 1 0 0 1 1 1 1 Centromere-binding protein HTH domain ParBc PF02195.18 EHT97756.1 - 8.3e-12 45.2 0.1 5.5e-11 42.6 0.0 2.3 3 0 0 3 3 3 1 ParB-like nuclease domain AAA_31 PF13614.6 EHT97757.1 - 4.3e-28 98.4 0.0 6e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 EHT97757.1 - 3.1e-14 53.1 0.0 4.2e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 EHT97757.1 - 2.3e-05 23.8 0.2 0.013 14.8 0.0 2.3 2 0 0 2 2 2 2 ATPase MipZ ArsA_ATPase PF02374.15 EHT97757.1 - 0.00013 21.3 0.2 0.021 14.0 0.0 2.3 2 0 0 2 2 2 2 Anion-transporting ATPase VirC1 PF07015.11 EHT97757.1 - 0.00098 18.5 0.1 0.11 11.7 0.0 2.5 2 0 0 2 2 2 1 VirC1 protein MerR PF00376.23 EHT97757.1 - 0.0044 16.8 0.0 0.015 15.1 0.0 1.9 2 0 0 2 2 2 1 MerR family regulatory protein PI-PLC-X PF00388.19 EHT97757.1 - 0.017 14.7 0.0 0.7 9.5 0.0 2.2 2 0 0 2 2 2 0 Phosphatidylinositol-specific phospholipase C, X domain Phage_Cox PF10743.9 EHT97757.1 - 0.051 13.7 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 Regulatory phage protein cox HTH_17 PF12728.7 EHT97757.1 - 0.053 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3853 PF12964.7 EHT97757.1 - 0.065 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3853) CBP_BcsQ PF06564.12 EHT97757.1 - 0.082 12.4 0.1 0.9 9.0 0.0 2.5 2 1 0 2 2 2 0 Cellulose biosynthesis protein BcsQ ParA PF10609.9 EHT97757.1 - 0.084 12.3 0.6 0.22 10.9 0.1 1.8 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase HTH_10 PF04967.12 EHT97757.1 - 0.13 12.1 0.0 0.69 9.8 0.0 2.1 2 0 0 2 2 2 0 HTH DNA binding domain HTH_3 PF01381.22 EHT97757.1 - 0.15 12.2 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix MerR_1 PF13411.6 EHT97757.1 - 0.19 11.9 0.0 0.46 10.6 0.0 1.6 1 1 0 1 1 1 0 MerR HTH family regulatory protein HTH_Tnp_1 PF01527.20 EHT97758.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT97758.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT97758.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT97758.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHT97759.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHT97760.1 - 2.8e-98 328.9 3.0 1.9e-97 326.1 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT97760.1 - 3.3e-16 59.2 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT97760.1 - 1.4e-14 54.2 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT97760.1 - 1.2e-11 45.2 9.0 2.6e-11 44.1 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHT97760.1 - 0.017 14.9 6.4 0.027 14.3 6.4 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Phage_HK97_TLTM PF06120.11 EHT97760.1 - 0.022 14.0 1.7 0.042 13.0 1.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHT97760.1 - 0.022 15.1 4.3 0.091 13.1 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain FUSC PF04632.12 EHT97760.1 - 0.038 12.5 6.8 0.06 11.9 6.8 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 EHT97760.1 - 0.04 13.5 2.2 0.047 13.2 0.8 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Tho2 PF11262.8 EHT97760.1 - 0.057 12.6 0.5 0.094 11.9 0.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Troponin PF00992.20 EHT97760.1 - 0.062 13.6 3.0 0.11 12.8 3.0 1.3 1 0 0 1 1 1 0 Troponin LXG PF04740.12 EHT97760.1 - 0.11 12.2 2.5 0.32 10.7 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily UME PF08064.13 EHT97760.1 - 0.15 12.0 0.5 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain ERM PF00769.19 EHT97760.1 - 0.16 11.8 10.8 0.26 11.1 10.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HalX PF08663.10 EHT97760.1 - 0.23 11.8 3.1 0.59 10.5 3.1 1.7 1 0 0 1 1 1 0 HalX domain DHR10 PF18595.1 EHT97760.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Zn-ribbon_8 PF09723.10 EHT97760.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF1192 PF06698.11 EHT97760.1 - 0.53 10.4 5.3 3.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHT97760.1 - 1.1 8.4 3.1 1.7 7.8 3.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHT97760.1 - 2.8 7.4 7.9 6.1 6.3 7.9 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHT97760.1 - 3.3 8.1 7.9 6.7 7.0 7.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 EHT97760.1 - 7.1 7.3 8.7 7.7 7.2 1.0 3.0 1 1 1 2 2 2 0 SlyX N_NLPC_P60 PF12912.7 EHT97761.1 - 0.0097 16.3 0.0 0.0097 16.3 0.0 1.1 1 0 0 1 1 1 1 NLPC_P60 stabilising domain, N term Shigella_OspC PF06128.11 EHT97762.1 - 2e-47 162.3 9.8 3.2e-47 161.7 9.8 1.3 1 0 0 1 1 1 1 Shigella flexneri OspC protein rve PF00665.26 EHT97763.1 - 1.6e-23 83.1 0.0 2.6e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 EHT97763.1 - 3.5e-16 58.7 0.0 6.3e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 EHT97763.1 - 3.8e-09 36.6 0.0 1.5e-08 34.6 0.0 2.0 2 0 0 2 2 2 1 HTH-like domain Phe_ZIP PF08916.11 EHT97763.1 - 0.71 10.6 0.1 0.71 10.6 0.1 2.4 3 0 0 3 3 3 0 Phenylalanine zipper HTH_Tnp_1 PF01527.20 EHT97764.1 - 8e-14 51.7 0.2 5.5e-13 49.0 0.1 2.1 2 0 0 2 2 2 1 Transposase HTH_28 PF13518.6 EHT97764.1 - 0.019 15.1 0.0 0.1 12.8 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 EHT97764.1 - 0.042 13.7 0.0 0.1 12.4 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain HTH_29 PF13551.6 EHT97764.1 - 0.095 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix DUF4982 PF16355.5 EHT97764.1 - 0.098 12.6 0.0 0.52 10.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4982) DDE_Tnp_1 PF01609.21 EHT97765.1 - 2.9e-19 69.6 0.7 5.8e-19 68.6 0.7 1.4 1 1 0 1 1 1 1 Transposase DDE domain Toprim_Crpt PF13342.6 EHT97766.1 - 1.8e-12 47.0 3.6 2.1e-12 46.8 3.6 1.1 1 0 0 1 1 1 1 C-terminal repeat of topoisomerase Histone_HNS PF00816.21 EHT97767.1 - 2.6e-12 47.4 1.6 3.5e-12 47.0 1.6 1.2 1 0 0 1 1 1 1 H-NS histone family AAA_10 PF12846.7 EHT97768.1 - 4.4e-06 25.8 0.0 6.8e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain DUF87 PF01935.17 EHT97768.1 - 0.00015 21.9 0.0 0.00022 21.4 0.0 1.3 1 0 0 1 1 1 1 Helicase HerA, central domain T4SS-DNA_transf PF02534.14 EHT97768.1 - 0.011 14.6 0.0 0.022 13.6 0.0 1.5 1 1 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer TrwB_AAD_bind PF10412.9 EHT97768.1 - 0.032 13.2 0.0 0.048 12.6 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain CcdB PF01845.17 EHT97769.1 - 9.9e-20 70.6 0.4 1.2e-19 70.4 0.4 1.0 1 0 0 1 1 1 1 CcdB protein CcdA PF07362.12 EHT97770.1 - 7.4e-19 68.0 1.5 7.8e-19 67.9 1.5 1.0 1 0 0 1 1 1 1 Post-segregation antitoxin CcdA PNKP-ligase_C PF16536.5 EHT97770.1 - 0.1 12.8 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 PNKP adenylyltransferase domain, C-terminal region DDE_Tnp_1 PF01609.21 EHT97772.1 - 5.5e-20 71.9 0.0 1e-19 71.0 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DUF5638 PF18688.1 EHT97774.1 - 0.014 15.7 1.5 0.016 15.5 1.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5638) HTH_Tnp_1 PF01527.20 EHT97776.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT97776.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT97776.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT97776.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHT97777.1 - 7.5e-39 131.7 0.0 8.4e-39 131.6 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHT97778.1 - 2.7e-97 325.7 4.0 1.2e-96 323.5 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT97778.1 - 3.3e-16 59.2 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT97778.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT97778.1 - 8.7e-11 42.4 9.0 1.9e-10 41.4 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Phage_HK97_TLTM PF06120.11 EHT97778.1 - 0.011 15.0 0.8 0.021 14.0 0.8 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHT97778.1 - 0.02 15.2 4.2 0.084 13.2 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain UME PF08064.13 EHT97778.1 - 0.032 14.1 0.3 20 5.1 0.0 3.1 2 1 1 3 3 3 0 UME (NUC010) domain Exonuc_VII_L PF02601.15 EHT97778.1 - 0.039 13.5 2.7 0.04 13.5 1.0 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Troponin PF00992.20 EHT97778.1 - 0.044 14.1 2.8 0.078 13.3 2.8 1.3 1 0 0 1 1 1 0 Troponin FUSC PF04632.12 EHT97778.1 - 0.048 12.2 7.4 0.077 11.5 7.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tho2 PF11262.8 EHT97778.1 - 0.049 12.8 0.6 0.081 12.1 0.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FAM184 PF15665.5 EHT97778.1 - 0.052 13.3 8.0 0.082 12.7 8.0 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B HalX PF08663.10 EHT97778.1 - 0.13 12.6 2.4 0.34 11.3 2.4 1.7 1 0 0 1 1 1 0 HalX domain LXG PF04740.12 EHT97778.1 - 0.14 11.8 2.8 0.35 10.5 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHT97778.1 - 0.19 11.5 11.1 0.31 10.8 11.1 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DHR10 PF18595.1 EHT97778.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Zn-ribbon_8 PF09723.10 EHT97778.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF1192 PF06698.11 EHT97778.1 - 0.54 10.4 5.3 3.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHT97778.1 - 0.82 8.9 3.0 1.2 8.3 3.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHT97778.1 - 2 8.0 8.1 4.3 6.8 8.1 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHT97778.1 - 4.2 7.7 8.6 8.7 6.7 8.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CREPT PF16566.5 EHT97778.1 - 5.9 7.1 8.7 2.7 8.1 5.6 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour SlyX PF04102.12 EHT97778.1 - 9.7 6.9 9.0 18 6.1 2.3 3.0 1 1 1 2 2 2 0 SlyX N_NLPC_P60 PF12912.7 EHT97779.1 - 0.0097 16.3 0.0 0.0097 16.3 0.0 1.1 1 0 0 1 1 1 1 NLPC_P60 stabilising domain, N term DUF1460 PF07313.12 EHT97780.1 - 8.4e-76 254.1 0.0 1.1e-75 253.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1460) DDE_Tnp_Tn3 PF01526.17 EHT97782.1 - 1.4e-21 76.8 0.0 1.5e-21 76.6 0.0 1.0 1 0 0 1 1 1 1 Tn3 transposase DDE domain Resolvase PF00239.21 EHT97784.1 - 9.1e-47 158.8 1.0 1.3e-46 158.4 1.0 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_32 PF13565.6 EHT97784.1 - 0.0002 21.9 5.1 0.00068 20.2 0.7 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 EHT97784.1 - 0.00024 21.1 1.4 0.0029 17.6 0.0 2.3 1 1 1 2 2 2 1 Winged helix-turn helix HTH_38 PF13936.6 EHT97784.1 - 0.00057 19.6 0.1 0.002 17.8 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 EHT97784.1 - 0.00083 18.7 0.1 0.002 17.5 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.6 EHT97784.1 - 0.0024 17.9 0.1 0.0056 16.8 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_7 PF02796.15 EHT97784.1 - 0.011 15.8 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 EHT97784.1 - 0.04 13.7 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_17 PF12728.7 EHT97784.1 - 0.062 13.5 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 EHT97784.1 - 0.093 12.4 0.6 0.37 10.5 0.0 2.1 2 1 0 2 2 2 0 Sigma-70, region 4 FliT PF05400.13 EHT97784.1 - 0.23 12.3 4.5 0.11 13.3 1.3 2.0 2 1 0 2 2 2 0 Flagellar protein FliT HTH_33 PF13592.6 EHT97784.1 - 0.31 10.7 1.8 12 5.6 0.0 2.7 3 0 0 3 3 3 0 Winged helix-turn helix DDE_Tnp_Tn3 PF01526.17 EHT97786.1 - 1.3e-87 294.1 0.0 1.5e-87 293.9 0.0 1.0 1 0 0 1 1 1 1 Tn3 transposase DDE domain HTH_31 PF13560.6 EHT97789.1 - 0.02 15.2 0.0 0.023 15.0 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain MqsA_antitoxin PF15731.5 EHT97789.1 - 0.1 12.7 0.0 0.12 12.5 0.0 1.0 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA HTH_3 PF01381.22 EHT97790.1 - 0.0018 18.3 0.1 0.0034 17.4 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_29 PF13551.6 EHT97790.1 - 0.024 14.6 0.1 0.057 13.4 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn helix HTH_8 PF02954.19 EHT97790.1 - 0.027 14.3 1.4 0.027 14.2 0.2 1.7 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family HTH_7 PF02796.15 EHT97790.1 - 0.058 13.5 0.1 0.17 12.0 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 EHT97790.1 - 0.067 13.3 0.2 0.12 12.6 0.2 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_IclR PF09339.10 EHT97790.1 - 0.11 12.3 0.4 0.86 9.5 0.0 2.2 1 1 1 2 2 2 0 IclR helix-turn-helix domain Spindle_Spc25 PF08234.12 EHT97790.1 - 0.14 12.3 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Chromosome segregation protein Spc25 HTH_37 PF13744.6 EHT97791.1 - 2.5e-10 40.2 0.1 2.9e-10 40.0 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 EHT97791.1 - 2.8e-10 40.1 0.0 4.5e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EHT97791.1 - 8.3e-09 35.7 0.1 1.1e-08 35.2 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 EHT97791.1 - 2e-05 24.5 0.0 3.8e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 EHT97791.1 - 0.00036 20.4 0.1 0.00054 19.8 0.1 1.4 1 0 0 1 1 1 1 MarR family Sigma70_r4 PF04545.16 EHT97791.1 - 0.00043 19.7 0.0 0.0012 18.3 0.0 1.7 1 1 1 2 2 2 1 Sigma-70, region 4 HTH_24 PF13412.6 EHT97791.1 - 0.00059 19.3 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_26 PF13443.6 EHT97791.1 - 0.0015 18.9 0.0 0.0039 17.6 0.0 1.6 2 0 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain HTH_1 PF00126.27 EHT97791.1 - 0.0054 16.7 0.3 0.015 15.2 0.1 1.9 1 1 1 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR PF01047.22 EHT97791.1 - 0.01 15.7 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_23 PF13384.6 EHT97791.1 - 0.03 14.1 0.0 0.075 12.9 0.0 1.8 1 1 0 1 1 1 0 Homeodomain-like domain YdaS_antitoxin PF15943.5 EHT97791.1 - 0.035 14.0 0.1 0.074 12.9 0.1 1.6 1 1 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Fe_dep_repress PF01325.19 EHT97791.1 - 0.065 13.5 0.1 0.13 12.5 0.0 1.5 1 1 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Peptidase_S41 PF03572.18 EHT97791.1 - 0.08 12.5 0.0 0.084 12.4 0.0 1.1 1 0 0 1 1 1 0 Peptidase family S41 HTH_10 PF04967.12 EHT97791.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain DnaJ PF00226.31 EHT97792.1 - 4.5e-10 39.5 0.0 6e-10 39.1 0.0 1.4 1 1 0 1 1 1 1 DnaJ domain TnpB_IS66 PF05717.13 EHT97793.1 - 7.5e-17 61.1 0.1 8.2e-17 61.0 0.1 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHT97794.1 - 4.5e-98 328.2 3.0 1e-97 327.0 0.0 2.0 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT97794.1 - 5.6e-17 61.7 0.0 2.1e-16 59.8 0.0 2.1 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT97794.1 - 8.4e-15 54.9 2.3 2.2e-14 53.6 2.3 1.8 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT97794.1 - 2.6e-12 47.3 6.0 5.7e-12 46.2 6.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Troponin PF00992.20 EHT97794.1 - 0.0089 16.3 1.2 0.017 15.4 1.2 1.4 1 0 0 1 1 1 1 Troponin Shugoshin_N PF07558.11 EHT97794.1 - 0.026 14.4 0.3 0.076 12.9 0.3 1.8 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region FAM184 PF15665.5 EHT97794.1 - 0.026 14.3 5.1 0.042 13.6 5.1 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Csm1_N PF18504.1 EHT97794.1 - 0.068 13.5 2.9 0.15 12.4 1.1 2.3 1 1 1 2 2 2 0 Csm1 N-terminal domain LXG PF04740.12 EHT97794.1 - 0.13 12.0 0.9 0.52 10.0 0.5 2.0 1 1 1 2 2 2 0 LXG domain of WXG superfamily HAUS-augmin3 PF14932.6 EHT97794.1 - 0.16 11.5 4.9 0.17 11.5 3.2 1.8 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF1192 PF06698.11 EHT97794.1 - 0.17 12.0 2.9 1.6 8.8 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Exonuc_VII_L PF02601.15 EHT97794.1 - 0.24 10.9 1.1 0.75 9.3 0.3 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit FUSC PF04632.12 EHT97794.1 - 0.28 9.7 9.2 0.038 12.5 4.7 1.8 2 0 0 2 2 2 0 Fusaric acid resistance protein family ERM PF00769.19 EHT97794.1 - 0.9 9.3 9.7 1.5 8.6 9.7 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF1471 PF07338.13 EHT97795.1 - 5e-08 32.8 1.1 8.1e-08 32.1 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1471) DUF4179 PF13786.6 EHT97795.1 - 0.0072 16.8 1.0 0.008 16.6 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4179) PepSY_2 PF13670.6 EHT97795.1 - 0.032 14.2 1.1 0.038 14.0 1.1 1.1 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain TcpQ PF10671.9 EHT97795.1 - 0.07 13.3 0.1 0.091 12.9 0.1 1.2 1 0 0 1 1 1 0 Toxin co-regulated pilus biosynthesis protein Q HTH_Tnp_1 PF01527.20 EHT97797.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT97797.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT97797.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT97797.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHT97798.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHT97799.1 - 1.3e-97 326.7 3.8 3.8e-97 325.1 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT97799.1 - 3e-16 59.3 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT97799.1 - 1.4e-14 54.2 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT97799.1 - 8.8e-11 42.4 8.7 1.9e-10 41.4 8.7 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHT97799.1 - 0.023 14.5 5.9 0.036 13.8 5.9 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Phage_HK97_TLTM PF06120.11 EHT97799.1 - 0.028 13.6 1.5 0.054 12.7 1.5 1.4 1 0 0 1 1 1 0 Tail length tape measure protein FUSC PF04632.12 EHT97799.1 - 0.03 12.9 6.3 0.048 12.2 6.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Csm1_N PF18504.1 EHT97799.1 - 0.032 14.6 4.4 0.12 12.8 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Tho2 PF11262.8 EHT97799.1 - 0.044 13.0 0.5 0.074 12.2 0.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Exonuc_VII_L PF02601.15 EHT97799.1 - 0.096 12.2 2.0 0.12 11.9 0.7 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit ERM PF00769.19 EHT97799.1 - 0.14 11.9 9.9 0.23 11.2 9.9 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family UME PF08064.13 EHT97799.1 - 0.17 11.8 0.5 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain HalX PF08663.10 EHT97799.1 - 0.19 12.1 3.0 0.49 10.7 3.0 1.7 1 0 0 1 1 1 0 HalX domain LXG PF04740.12 EHT97799.1 - 0.29 10.8 2.3 1.1 9.0 0.3 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily Zn-ribbon_8 PF09723.10 EHT97799.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DHR10 PF18595.1 EHT97799.1 - 0.52 10.4 10.4 0.91 9.6 10.4 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF1192 PF06698.11 EHT97799.1 - 1 9.4 6.1 4 7.6 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) HAUS-augmin3 PF14932.6 EHT97799.1 - 4.2 6.9 7.3 9.3 5.7 7.3 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 SlyX PF04102.12 EHT97799.1 - 6.1 7.5 8.3 8.1 7.1 1.0 3.0 1 1 0 2 2 2 0 SlyX DDE_3 PF13358.6 EHT97800.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHT97800.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHT97800.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHT97800.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHT97800.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHT97800.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHT97800.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHT97800.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 T4SS PF07996.11 EHT97801.1 - 2.6e-47 161.8 9.3 3.4e-47 161.4 9.3 1.1 1 0 0 1 1 1 1 Type IV secretion system proteins Peptidase_M16_C PF05193.21 EHT97801.1 - 0.013 15.6 0.5 0.045 13.8 0.1 1.9 1 1 1 2 2 2 0 Peptidase M16 inactive domain DUF948 PF06103.11 EHT97801.1 - 0.21 11.9 3.5 14 6.0 2.4 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Seryl_tRNA_N PF02403.22 EHT97801.1 - 0.4 10.9 8.9 2.1 8.6 3.0 2.8 2 2 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF5344 PF17279.2 EHT97801.1 - 1 10.0 8.7 0.76 10.4 0.2 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5344) CagE_TrbE_VirB PF03135.14 EHT97802.1 - 5.1e-43 147.6 0.0 1.1e-42 146.5 0.0 1.6 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system VirB3 PF05101.13 EHT97802.1 - 9.4e-13 48.2 4.5 2.3e-12 47.0 4.5 1.6 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein TrwB_AAD_bind PF10412.9 EHT97802.1 - 0.005 15.8 0.0 0.52 9.1 0.0 2.2 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_15 PF13175.6 EHT97802.1 - 0.016 14.9 0.0 0.051 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 EHT97802.1 - 0.024 15.1 0.0 0.33 11.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain TrbC PF04956.13 EHT97803.1 - 3.3e-20 72.2 4.3 3.5e-20 72.1 4.3 1.0 1 0 0 1 1 1 1 TrbC/VIRB2 family SLT PF01464.20 EHT97804.1 - 2.7e-16 59.3 0.0 3.9e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase SLT domain LIX1 PF14954.6 EHT97806.1 - 0.18 11.1 1.9 0.22 10.8 1.9 1.1 1 0 0 1 1 1 0 Limb expression 1 IncFII_repA PF02387.15 EHT97807.1 - 1.3e-09 37.7 0.0 1.4e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 IncFII RepA protein family FUSC_2 PF13515.6 EHT97808.1 - 2.6e-12 47.0 7.8 4e-12 46.4 7.8 1.2 1 0 0 1 1 1 1 Fusaric acid resistance protein-like Aminotran_3 PF00202.21 EHT97809.1 - 2.9e-134 447.8 0.0 3.6e-134 447.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EHT97809.1 - 1.2e-05 24.7 0.0 1.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EHT97809.1 - 0.036 13.0 0.1 0.13 11.2 0.0 1.8 1 1 0 1 1 1 0 Aminotransferase class-V GATase PF00117.28 EHT97810.1 - 1.1e-54 185.1 0.0 1.3e-54 184.9 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EHT97810.1 - 2e-08 34.2 0.2 7e-08 32.5 0.2 1.7 1 1 0 1 1 1 1 Peptidase C26 DDE_Tnp_IS66 PF03050.14 EHT97811.1 - 1.3e-97 326.7 3.8 3.8e-97 325.1 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT97811.1 - 3e-16 59.3 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT97811.1 - 1.4e-14 54.2 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT97811.1 - 8.8e-11 42.4 8.7 1.9e-10 41.4 8.7 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHT97811.1 - 0.023 14.5 5.9 0.036 13.8 5.9 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Phage_HK97_TLTM PF06120.11 EHT97811.1 - 0.028 13.6 1.5 0.054 12.7 1.5 1.4 1 0 0 1 1 1 0 Tail length tape measure protein FUSC PF04632.12 EHT97811.1 - 0.03 12.9 6.3 0.048 12.2 6.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Csm1_N PF18504.1 EHT97811.1 - 0.032 14.6 4.4 0.12 12.8 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Tho2 PF11262.8 EHT97811.1 - 0.044 13.0 0.5 0.074 12.2 0.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Exonuc_VII_L PF02601.15 EHT97811.1 - 0.096 12.2 2.0 0.12 11.9 0.7 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit ERM PF00769.19 EHT97811.1 - 0.14 11.9 9.9 0.23 11.2 9.9 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family UME PF08064.13 EHT97811.1 - 0.17 11.8 0.5 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain HalX PF08663.10 EHT97811.1 - 0.19 12.1 3.0 0.49 10.7 3.0 1.7 1 0 0 1 1 1 0 HalX domain LXG PF04740.12 EHT97811.1 - 0.29 10.8 2.3 1.1 9.0 0.3 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily Zn-ribbon_8 PF09723.10 EHT97811.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DHR10 PF18595.1 EHT97811.1 - 0.52 10.4 10.4 0.91 9.6 10.4 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF1192 PF06698.11 EHT97811.1 - 1 9.4 6.1 4 7.6 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) HAUS-augmin3 PF14932.6 EHT97811.1 - 4.2 6.9 7.3 9.3 5.7 7.3 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 SlyX PF04102.12 EHT97811.1 - 6.1 7.5 8.3 8.1 7.1 1.0 3.0 1 1 0 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHT97812.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHT97813.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT97813.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT97813.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT97813.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix Topoisom_bac PF01131.20 EHT97815.1 - 1.7e-90 304.0 0.4 2e-90 303.8 0.4 1.0 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 EHT97815.1 - 0.089 13.0 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 Toprim domain RBB1NT PF08169.11 EHT97815.1 - 0.095 12.9 0.1 13 6.1 0.0 2.6 2 0 0 2 2 2 0 RBB1NT (NUC162) domain TraG-D_C PF12696.7 EHT97816.1 - 1.6e-09 37.8 0.0 2.7e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TrwB_AAD_bind PF10412.9 EHT97816.1 - 2.3e-08 33.4 0.0 3e-08 33.0 0.0 1.0 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain SNase PF00565.17 EHT97818.1 - 1.4e-25 89.9 0.1 1.7e-25 89.6 0.1 1.1 1 0 0 1 1 1 1 Staphylococcal nuclease homologue DUF1449 PF07290.11 EHT97819.1 - 0.025 14.2 0.2 0.027 14.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) DUF2975 PF11188.8 EHT97819.1 - 0.049 13.5 0.2 0.057 13.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) DUF3413 PF11893.8 EHT97819.1 - 0.21 10.7 1.1 0.29 10.2 1.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3413) SNN_transmemb PF09049.10 EHT97819.1 - 0.38 10.7 3.4 0.74 9.8 3.4 1.5 1 1 0 1 1 1 0 Stannin transmembrane SprT-like PF10263.9 EHT97822.1 - 1.8e-05 24.6 0.0 2.8e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 SprT-like family BSP PF04450.12 EHT97822.1 - 0.028 14.2 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase of plants and bacteria Peptidase_M91 PF14891.6 EHT97822.1 - 0.22 11.8 0.0 0.32 11.3 0.0 1.2 1 0 0 1 1 1 0 Effector protein DUF4956 PF16316.5 EHT97824.1 - 0.033 13.9 0.9 0.031 13.9 0.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4956) CcdB PF01845.17 EHT97825.1 - 1.1e-29 102.6 0.0 1.2e-29 102.5 0.0 1.0 1 0 0 1 1 1 1 CcdB protein CcdA PF07362.12 EHT97826.1 - 3.2e-25 88.3 1.4 3.4e-25 88.2 1.4 1.0 1 0 0 1 1 1 1 Post-segregation antitoxin CcdA HTH_Tnp_1 PF01527.20 EHT97828.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT97828.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT97828.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT97828.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHT97829.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHT97830.1 - 1.2e-97 326.8 2.7 1.2e-96 323.5 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT97830.1 - 3.3e-16 59.2 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT97830.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT97830.1 - 8.9e-12 45.6 8.5 1.9e-11 44.6 8.5 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FUSC PF04632.12 EHT97830.1 - 0.046 12.3 7.1 0.072 11.6 7.1 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Phage_HK97_TLTM PF06120.11 EHT97830.1 - 0.046 12.9 1.3 0.09 12.0 1.3 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Exonuc_VII_L PF02601.15 EHT97830.1 - 0.05 13.2 1.7 0.072 12.6 0.5 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit LXG PF04740.12 EHT97830.1 - 0.1 12.3 1.6 0.81 9.4 0.3 2.2 1 1 1 2 2 2 0 LXG domain of WXG superfamily Csm1_N PF18504.1 EHT97830.1 - 0.13 12.6 3.2 0.93 9.9 0.2 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain FAM184 PF15665.5 EHT97830.1 - 0.15 11.8 4.7 0.24 11.2 4.7 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B DHR10 PF18595.1 EHT97830.1 - 0.18 11.9 10.2 0.31 11.1 10.2 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain HalX PF08663.10 EHT97830.1 - 0.22 11.8 2.3 0.6 10.5 2.3 1.7 1 0 0 1 1 1 0 HalX domain ALIX_LYPXL_bnd PF13949.6 EHT97830.1 - 0.23 10.7 4.0 0.39 9.9 4.0 1.3 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV TSNAXIP1_N PF15739.5 EHT97830.1 - 0.26 11.7 2.9 0.56 10.6 2.9 1.5 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus ERM PF00769.19 EHT97830.1 - 0.29 10.9 10.4 0.48 10.2 10.4 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HHH_8 PF14716.6 EHT97830.1 - 0.36 11.2 4.1 0.92 9.9 2.6 2.4 2 1 0 2 2 2 0 Helix-hairpin-helix domain Zn-ribbon_8 PF09723.10 EHT97830.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain CREPT PF16566.5 EHT97830.1 - 0.48 10.6 7.6 0.22 11.7 4.5 1.8 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour HAUS-augmin3 PF14932.6 EHT97830.1 - 1.2 8.6 6.9 2.9 7.4 6.9 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 ABC_tran_CTD PF16326.5 EHT97830.1 - 2 8.7 6.7 0.3 11.4 1.2 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain SlyX PF04102.12 EHT97830.1 - 7.6 7.2 8.3 15 6.3 1.9 3.0 1 1 1 2 2 2 0 SlyX DnaJ PF00226.31 EHT97831.1 - 1.4e-10 41.1 0.0 2e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Gp49 PF05973.14 EHT97832.1 - 1.5e-22 79.6 0.0 1.7e-22 79.4 0.0 1.0 1 0 0 1 1 1 1 Phage derived protein Gp49-like (DUF891) ParE_toxin PF05016.15 EHT97832.1 - 0.069 13.8 0.0 0.098 13.3 0.0 1.3 1 0 0 1 1 1 0 ParE toxin of type II toxin-antitoxin system, parDE PIN PF01850.21 EHT97833.1 - 4.8e-05 23.9 0.0 0.0001 22.8 0.0 1.7 1 1 0 1 1 1 1 PIN domain VapB_antitoxin PF09957.9 EHT97834.1 - 2.8e-06 27.1 0.3 3.5e-06 26.8 0.3 1.1 1 0 0 1 1 1 1 Bacterial antitoxin of type II TA system, VapB DUF2802 PF10975.8 EHT97834.1 - 0.14 12.3 0.1 0.38 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) SRP72 PF08492.12 EHT97836.1 - 0.1 13.0 1.0 0.16 12.4 1.0 1.3 1 0 0 1 1 1 0 SRP72 RNA-binding domain DDE_3 PF13358.6 EHT97837.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHT97837.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHT97837.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHT97837.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHT97837.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHT97837.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHT97837.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHT97837.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 HTH_Tnp_ISL3 PF13542.6 EHT97839.1 - 6.8e-13 47.8 0.0 1.4e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 DDE_Tnp_ISL3 PF01610.17 EHT97839.1 - 1e-12 48.3 0.0 1.6e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Transposase zf-ISL3 PF14690.6 EHT97839.1 - 6.2e-10 39.6 7.3 1.3e-09 38.6 7.3 1.6 1 0 0 1 1 1 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 FANCI_S1-cap PF14674.6 EHT97839.1 - 0.15 12.2 0.4 0.28 11.3 0.4 1.4 1 0 0 1 1 1 0 FANCI solenoid 1 cap DDE_Tnp_ISL3 PF01610.17 EHT97840.1 - 0.078 12.7 1.1 0.075 12.7 1.1 1.0 1 0 0 1 1 1 0 Transposase DDE_3 PF13358.6 EHT97841.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHT97841.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHT97841.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHT97841.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHT97841.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHT97841.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHT97841.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHT97841.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 Resolvase PF00239.21 EHT97842.1 - 9.6e-42 142.5 1.1 1.2e-41 142.2 1.1 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_7 PF02796.15 EHT97842.1 - 5.1e-09 36.1 0.8 1.2e-08 34.9 0.2 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 EHT97842.1 - 0.0011 18.7 0.6 0.0011 18.7 0.6 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_20 PF12840.7 EHT97842.1 - 0.0033 17.5 0.2 29 4.8 0.0 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT97842.1 - 0.0036 17.3 1.7 0.15 12.1 0.0 2.9 2 1 1 3 3 3 1 Winged helix-turn helix HTH_Tnp_IS630 PF01710.16 EHT97842.1 - 0.011 15.8 0.0 0.028 14.4 0.0 1.7 1 0 0 1 1 1 0 Transposase TrmB PF01978.19 EHT97842.1 - 0.037 13.9 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 EHT97842.1 - 0.079 12.8 0.1 0.21 11.4 0.1 1.9 1 1 0 1 1 1 0 IclR helix-turn-helix domain HTH_38 PF13936.6 EHT97842.1 - 0.11 12.3 3.7 0.14 12.0 0.3 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain PAX PF00292.18 EHT97842.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 'Paired box' domain DUF4158 PF13700.6 EHT97843.1 - 3.8e-16 59.4 0.0 4.2e-16 59.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4158) DDE_3 PF13358.6 EHT97844.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHT97844.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHT97844.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHT97844.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHT97844.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHT97844.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHT97844.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHT97844.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 DUF1460 PF07313.12 EHT97845.1 - 8.4e-76 254.1 0.0 1.1e-75 253.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1460) N_NLPC_P60 PF12912.7 EHT97846.1 - 0.0097 16.3 0.0 0.0097 16.3 0.0 1.1 1 0 0 1 1 1 1 NLPC_P60 stabilising domain, N term SH3_7 PF12914.7 EHT97847.1 - 7.2e-12 45.3 0.0 1.5e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain of SH3b2 type SH3_6 PF12913.7 EHT97847.1 - 5e-10 38.8 0.1 1.1e-09 37.7 0.1 1.7 1 0 0 1 1 1 1 SH3 domain (SH3b1 type) NLPC_P60 PF00877.19 EHT97847.1 - 3.7e-06 26.9 0.0 6.7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 NlpC/P60 family FAINT PF04385.15 EHT97848.1 - 0.091 12.8 0.5 0.2 11.8 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function, DUF529 Amidase_2 PF01510.25 EHT97849.1 - 8.5e-24 84.4 0.0 1.4e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase PG_binding_1 PF01471.18 EHT97849.1 - 0.00022 21.4 0.0 0.00046 20.3 0.0 1.6 1 0 0 1 1 1 1 Putative peptidoglycan binding domain HTH_7 PF02796.15 EHT97850.1 - 1.1e-10 41.4 0.1 4.9e-10 39.3 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase Resolvase PF00239.21 EHT97850.1 - 1.9e-06 28.1 0.2 3.6e-06 27.1 0.1 1.5 2 0 0 2 2 2 1 Resolvase, N terminal domain HTH_38 PF13936.6 EHT97850.1 - 2.7e-05 23.8 0.5 5.3e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 EHT97850.1 - 8e-05 22.6 0.1 0.00032 20.7 0.0 1.8 1 1 1 2 2 2 1 Winged helix-turn helix HTH_11 PF08279.12 EHT97850.1 - 0.0002 21.2 0.0 0.00031 20.6 0.0 1.3 1 0 0 1 1 1 1 HTH domain HTH_32 PF13565.6 EHT97850.1 - 0.00029 21.4 0.1 0.00037 21.1 0.1 1.1 1 0 0 1 1 1 1 Homeodomain-like domain UPF0122 PF04297.14 EHT97850.1 - 0.00036 20.7 0.0 0.0005 20.3 0.0 1.1 1 0 0 1 1 1 1 Putative helix-turn-helix protein, YlxM / p13 like HTH_23 PF13384.6 EHT97850.1 - 0.00082 19.1 0.0 0.002 17.9 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_22 PF13309.6 EHT97850.1 - 0.00095 19.2 0.1 0.0016 18.4 0.1 1.6 1 1 0 1 1 1 1 HTH domain HTH_17 PF12728.7 EHT97850.1 - 0.0015 18.7 0.0 0.0031 17.7 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 EHT97850.1 - 0.003 17.4 0.0 0.0047 16.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family Sigma70_r4_2 PF08281.12 EHT97850.1 - 0.01 15.5 0.5 0.021 14.5 0.1 1.7 2 0 0 2 2 2 0 Sigma-70, region 4 MarR PF01047.22 EHT97850.1 - 0.011 15.7 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_IclR PF09339.10 EHT97850.1 - 0.011 15.5 0.1 0.042 13.7 0.0 1.9 2 1 0 2 2 2 0 IclR helix-turn-helix domain HTH_6 PF01418.17 EHT97850.1 - 0.015 15.2 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_Tnp_4 PF13613.6 EHT97850.1 - 0.017 14.9 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_28 PF13518.6 EHT97850.1 - 0.017 15.2 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_psq PF05225.16 EHT97850.1 - 0.018 14.8 0.1 0.035 13.8 0.0 1.5 2 0 0 2 2 2 0 helix-turn-helix, Psq domain HTH_DeoR PF08220.12 EHT97850.1 - 0.023 14.5 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain DUF3574 PF12098.8 EHT97850.1 - 0.024 14.4 0.0 0.03 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3574) HTH_Tnp_1_2 PF13022.6 EHT97850.1 - 0.038 14.2 0.0 0.055 13.6 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase TrmB PF01978.19 EHT97850.1 - 0.039 13.8 0.0 0.049 13.5 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_36 PF13730.6 EHT97850.1 - 0.051 13.5 0.0 0.095 12.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Mga PF05043.13 EHT97850.1 - 0.061 13.9 0.0 0.13 12.9 0.0 1.6 2 0 0 2 2 2 0 Mga helix-turn-helix domain Sigma70_ECF PF07638.11 EHT97850.1 - 0.069 13.0 0.0 0.077 12.9 0.0 1.2 1 0 0 1 1 1 0 ECF sigma factor NUMOD1 PF07453.13 EHT97850.1 - 0.072 13.4 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 NUMOD1 domain HTH_Crp_2 PF13545.6 EHT97850.1 - 0.099 12.6 0.0 0.13 12.2 0.0 1.5 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain DDE_Tnp_Tn3 PF01526.17 EHT97851.1 - 1.3e-101 340.2 0.0 1.7e-101 339.9 0.0 1.2 1 0 0 1 1 1 1 Tn3 transposase DDE domain DUF4158 PF13700.6 EHT97851.1 - 2.3e-34 118.6 0.1 1.1e-33 116.4 0.1 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4158) DDE_Tnp_IS66 PF03050.14 EHT97852.1 - 1.1e-97 327.0 3.8 3.8e-97 325.2 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT97852.1 - 5.4e-18 64.9 0.1 2.2e-17 63.0 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT97852.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT97852.1 - 6.8e-11 42.8 8.3 1.5e-10 41.7 8.3 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Exonuc_VII_L PF02601.15 EHT97852.1 - 0.041 13.4 2.0 0.052 13.1 0.7 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit FUSC PF04632.12 EHT97852.1 - 0.044 12.3 6.9 0.071 11.6 6.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Phage_HK97_TLTM PF06120.11 EHT97852.1 - 0.054 12.7 1.5 0.11 11.7 1.5 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHT97852.1 - 0.15 12.4 3.6 0.93 9.9 0.3 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain UME PF08064.13 EHT97852.1 - 0.15 12.0 0.4 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain FAM184 PF15665.5 EHT97852.1 - 0.16 11.7 5.7 0.25 11.1 5.7 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B DHR10 PF18595.1 EHT97852.1 - 0.18 11.9 10.2 0.31 11.1 10.2 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Tho2 PF11262.8 EHT97852.1 - 0.19 10.9 0.3 0.32 10.2 0.3 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 LXG PF04740.12 EHT97852.1 - 0.22 11.2 2.2 0.81 9.4 0.3 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHT97852.1 - 0.23 11.2 10.2 0.38 10.5 10.2 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HHH_8 PF14716.6 EHT97852.1 - 0.29 11.5 3.7 0.55 10.6 1.8 2.4 2 1 0 2 2 2 0 Helix-hairpin-helix domain TSNAXIP1_N PF15739.5 EHT97852.1 - 0.47 10.9 3.2 0.99 9.8 3.2 1.5 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus Zn-ribbon_8 PF09723.10 EHT97852.1 - 0.55 10.4 2.4 0.92 9.7 0.2 2.3 2 0 0 2 2 2 0 Zinc ribbon domain TMPIT PF07851.13 EHT97852.1 - 1 8.5 2.7 1.6 7.9 2.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHT97852.1 - 4 6.9 7.4 9.4 5.7 7.4 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 SlyX PF04102.12 EHT97852.1 - 7.8 7.2 8.7 12 6.6 1.6 3.0 1 1 1 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHT97853.1 - 8.6e-12 44.9 0.0 9.4e-12 44.7 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHT97854.1 - 2.7e-10 40.4 0.0 5.4e-10 39.4 0.0 1.5 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.6 EHT97854.1 - 0.0054 16.5 0.0 0.0072 16.1 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 EHT97854.1 - 0.027 14.6 0.0 0.044 13.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Y2_Tnp PF04986.13 EHT97856.1 - 7.4e-11 42.4 0.8 1e-10 42.0 0.8 1.2 1 0 0 1 1 1 1 Putative transposase Desulfoferrod_N PF06397.12 EHT97856.1 - 0.097 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain Resolvase PF00239.21 EHT97857.1 - 4.4e-29 101.5 0.5 7.8e-29 100.7 0.5 1.4 1 0 0 1 1 1 1 Resolvase, N terminal domain LacI PF00356.21 EHT97857.1 - 2.5e-05 24.0 0.1 5.4e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family HTH_31 PF13560.6 EHT97857.1 - 0.0019 18.5 3.5 0.014 15.7 0.1 2.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 EHT97857.1 - 0.0027 17.7 1.4 0.0061 16.6 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix HTH_23 PF13384.6 EHT97857.1 - 0.003 17.3 0.4 0.0097 15.7 0.1 2.1 1 1 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 EHT97857.1 - 0.0036 17.0 0.1 0.0095 15.7 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain Pro_Al_protease PF02983.14 EHT97857.1 - 0.016 15.2 0.1 0.038 14.0 0.1 1.6 1 0 0 1 1 1 0 Alpha-lytic protease prodomain HTH_7 PF02796.15 EHT97857.1 - 0.044 13.9 0.2 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_Tnp_ISL3 PF13542.6 EHT97857.1 - 0.094 12.1 0.1 0.24 10.8 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Stn1_C PF12659.7 EHT97857.1 - 0.12 12.3 0.0 0.57 10.1 0.0 1.9 2 0 0 2 2 2 0 Telomere capping C-terminal wHTH Acetyltransf_10 PF13673.7 EHT97858.1 - 2.3e-05 24.3 0.0 0.00013 21.9 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EHT97858.1 - 4.4e-05 23.7 0.0 5.3e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EHT97858.1 - 0.0007 20.0 0.0 0.00096 19.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1778 PF08681.11 EHT97859.1 - 1.4e-06 28.1 0.1 1.4e-06 28.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1778) TraY PF05509.11 EHT97860.1 - 2.3e-13 50.0 1.2 1.1e-09 38.2 0.0 2.1 2 0 0 2 2 2 2 TraY domain TraA PF05513.11 EHT97862.1 - 6e-07 29.8 0.6 7.4e-07 29.5 0.6 1.2 1 0 0 1 1 1 1 TraA CRPA PF05745.11 EHT97862.1 - 0.39 10.7 2.3 0.61 10.1 2.3 1.3 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) TraL PF07178.11 EHT97863.1 - 3.8e-25 88.2 1.7 4.2e-25 88.0 1.7 1.0 1 0 0 1 1 1 1 TraL protein TraE PF05309.11 EHT97864.1 - 1.7e-38 131.8 0.0 1.9e-38 131.7 0.0 1.0 1 0 0 1 1 1 1 TraE protein TraK PF06586.11 EHT97865.1 - 1.5e-28 100.1 0.0 2e-28 99.7 0.0 1.0 1 0 0 1 1 1 1 TraK protein HTH_Tnp_1 PF01527.20 EHT97866.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT97866.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT97866.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT97866.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHT97867.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHT97868.1 - 4.6e-98 328.2 6.0 3.6e-97 325.2 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT97868.1 - 3.1e-16 59.3 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT97868.1 - 1.4e-14 54.2 1.5 3.3e-14 53.0 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT97868.1 - 1e-10 42.2 8.3 2.2e-10 41.1 8.3 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FUSC PF04632.12 EHT97868.1 - 0.0058 15.2 5.1 0.0093 14.6 5.1 1.3 1 0 0 1 1 1 1 Fusaric acid resistance protein family Csm1_N PF18504.1 EHT97868.1 - 0.011 16.0 5.4 0.087 13.2 0.3 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Phage_HK97_TLTM PF06120.11 EHT97868.1 - 0.025 13.8 2.1 0.049 12.8 2.1 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Exonuc_VII_L PF02601.15 EHT97868.1 - 0.027 14.1 2.6 0.029 13.9 1.0 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Tho2 PF11262.8 EHT97868.1 - 0.042 13.1 0.9 0.068 12.4 0.9 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 PRA-PH PF01503.17 EHT97868.1 - 0.12 12.9 0.5 11 6.5 0.1 2.7 3 0 0 3 3 2 0 Phosphoribosyl-ATP pyrophosphohydrolase DUF1192 PF06698.11 EHT97868.1 - 0.12 12.4 4.4 3.3 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) LXG PF04740.12 EHT97868.1 - 0.24 11.1 3.8 0.31 10.7 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily MIS13 PF08202.11 EHT97868.1 - 0.39 9.9 4.4 0.39 10.0 3.3 1.4 2 0 0 2 2 2 0 Mis12-Mtw1 protein family DHR10 PF18595.1 EHT97868.1 - 0.45 10.6 11.4 0.78 9.8 11.4 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain ERM PF00769.19 EHT97868.1 - 0.47 10.2 12.8 0.77 9.5 12.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Zn-ribbon_8 PF09723.10 EHT97868.1 - 0.52 10.5 2.3 0.95 9.6 0.2 2.3 2 0 0 2 2 2 0 Zinc ribbon domain ATG16 PF08614.11 EHT97868.1 - 0.91 9.7 10.9 9 6.5 10.5 2.1 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) FAM184 PF15665.5 EHT97868.1 - 1.2 8.9 10.0 1.9 8.2 10.0 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B OmpH PF03938.14 EHT97868.1 - 3 8.2 8.8 6.3 7.1 8.8 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TMPIT PF07851.13 EHT97868.1 - 3.4 6.8 4.6 5.3 6.2 4.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein WXG100 PF06013.12 EHT97868.1 - 3.9 7.8 5.8 1.9 8.8 2.5 2.2 2 1 0 2 2 2 0 Proteins of 100 residues with WXG HAUS-augmin3 PF14932.6 EHT97868.1 - 4.3 6.8 9.1 9.9 5.7 9.1 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 SlyX PF04102.12 EHT97868.1 - 8.6 7.1 9.3 8.2 7.1 1.1 3.1 1 1 2 3 3 3 0 SlyX TraF PF13728.6 EHT97870.1 - 6.2e-61 206.1 0.0 7.3e-61 205.8 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein PIN PF01850.21 EHT97871.1 - 5.5e-15 56.0 0.0 6.1e-15 55.8 0.0 1.0 1 0 0 1 1 1 1 PIN domain PIN_3 PF13470.6 EHT97871.1 - 0.054 14.3 0.0 0.061 14.1 0.0 1.1 1 0 0 1 1 1 0 PIN domain MazE_antitoxin PF04014.18 EHT97872.1 - 7.9e-06 25.7 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin NadA PF02445.16 EHT97873.1 - 0.19 10.8 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 Quinolinate synthetase A protein TraF PF13728.6 EHT97874.1 - 6.4e-13 49.0 0.0 7.7e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein DUF836 PF05768.14 EHT97874.1 - 0.023 15.1 0.0 0.042 14.2 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 EHT97874.1 - 0.082 13.4 0.1 0.15 12.5 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain DDE_3 PF13358.6 EHT97875.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHT97875.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHT97875.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHT97875.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHT97875.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHT97875.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHT97875.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHT97875.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 DDE_3 PF13358.6 EHT97877.1 - 1.4e-22 80.1 0.0 2.2e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 EHT97877.1 - 2.1e-10 40.1 1.5 4e-09 36.0 0.1 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 EHT97877.1 - 4.9e-09 36.7 1.1 3.2e-08 34.1 0.3 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 EHT97877.1 - 2.9e-07 30.4 1.3 1.2e-06 28.4 0.3 2.4 3 0 0 3 3 3 1 Winged helix-turn helix HTH_33 PF13592.6 EHT97877.1 - 2e-06 27.3 4.2 5e-06 26.1 0.3 2.9 3 0 0 3 3 3 1 Winged helix-turn helix HTH_28 PF13518.6 EHT97877.1 - 1.4e-05 25.1 0.6 0.00023 21.2 0.2 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHT97877.1 - 0.048 14.2 1.0 0.07 13.7 0.2 1.7 2 0 0 2 2 2 0 leucine-zipper of insertion element IS481 HTH_38 PF13936.6 EHT97877.1 - 0.057 13.2 0.6 0.17 11.7 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain MASE2 PF05230.11 EHT97878.1 - 0.22 11.6 4.9 0.28 11.3 4.9 1.2 1 0 0 1 1 1 0 MASE2 domain TraH PF06122.11 EHT97879.1 - 4.9e-104 348.5 5.5 4.9e-104 348.5 5.5 1.3 2 0 0 2 2 2 1 Conjugative relaxosome accessory transposon protein ApoLp-III PF07464.11 EHT97879.1 - 0.011 15.8 5.0 1.3 9.1 0.8 3.4 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) PHD_like PF12910.7 EHT97879.1 - 0.016 15.3 0.1 4 7.5 0.0 2.6 2 0 0 2 2 2 0 Antitoxin of toxin-antitoxin, RelE / RelB, TA system Med9 PF07544.13 EHT97879.1 - 0.2 11.7 5.8 0.5 10.5 2.1 2.9 3 0 0 3 3 2 0 RNA polymerase II transcription mediator complex subunit 9 FerA PF08165.11 EHT97879.1 - 0.23 11.5 2.7 1.8 8.6 0.9 3.1 2 1 1 3 3 3 0 FerA (NUC095) domain HrpB7 PF09486.10 EHT97879.1 - 0.37 11.2 6.7 0.29 11.5 3.1 2.5 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) Mod_r PF07200.13 EHT97879.1 - 0.49 10.5 9.9 0.17 12.0 6.3 2.0 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein COG2 PF06148.11 EHT97879.1 - 0.51 10.4 4.2 0.59 10.2 1.1 2.5 3 0 0 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DHR10 PF18595.1 EHT97879.1 - 0.55 10.3 8.7 0.44 10.6 5.8 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Rotamase PF00639.21 EHT97879.1 - 0.72 10.9 3.2 2.9 8.9 0.4 2.9 3 0 0 3 3 3 0 PPIC-type PPIASE domain SKA1 PF07160.12 EHT97879.1 - 0.94 9.3 5.7 0.81 9.5 2.9 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 H-kinase_dim PF02895.14 EHT97879.1 - 1.2 9.6 8.2 8.3 6.9 0.8 3.2 3 1 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain DUF4763 PF15960.5 EHT97879.1 - 1.4 8.1 8.3 0.85 8.9 4.5 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4763) Noelin-1 PF12308.8 EHT97879.1 - 1.7 8.7 4.7 28 4.7 2.4 2.7 2 0 0 2 2 2 0 Neurogenesis glycoprotein Helicase_IV_N PF12462.8 EHT97879.1 - 1.9 8.4 5.6 1.4 8.8 1.9 2.3 2 0 0 2 2 2 0 DNA helicase IV / RNA helicase N terminal HIP1_clath_bdg PF16515.5 EHT97879.1 - 2.2 9.0 10.8 2.3 8.9 5.7 2.8 3 0 0 3 3 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Prefoldin PF02996.17 EHT97879.1 - 4.3 7.3 9.8 0.67 9.9 3.1 2.9 3 0 0 3 3 3 0 Prefoldin subunit NPV_P10 PF05531.12 EHT97879.1 - 6.1 7.4 9.1 2.9 8.4 1.0 3.4 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein FliD_N PF02465.18 EHT97879.1 - 6.7 7.5 9.3 4.5 8.0 3.1 3.1 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus TraG_N PF07916.11 EHT97880.1 - 7.2e-98 328.5 22.0 7.2e-98 328.5 22.0 3.3 3 1 1 4 4 4 1 TraG-like protein, N-terminal region PMC2NT PF08066.12 EHT97880.1 - 0.071 13.8 0.5 0.071 13.8 0.5 3.3 3 0 0 3 3 3 0 PMC2NT (NUC016) domain TrwB_AAD_bind PF10412.9 EHT97881.1 - 2.2e-115 385.7 0.0 2.7e-115 385.4 0.0 1.1 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain TraG-D_C PF12696.7 EHT97881.1 - 7e-17 61.6 0.0 1.2e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG TraD_N PF12615.8 EHT97881.1 - 1.3e-11 45.1 2.7 2e-10 41.3 2.1 2.3 2 0 0 2 2 2 1 F sex factor protein N terminal T4SS-DNA_transf PF02534.14 EHT97881.1 - 3.5e-11 42.6 0.0 2.9e-10 39.6 0.0 2.0 1 1 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer AAA_16 PF13191.6 EHT97881.1 - 1.1e-05 25.9 0.0 0.00029 21.2 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 EHT97881.1 - 0.00031 20.2 0.0 0.00052 19.4 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family Viral_helicase1 PF01443.18 EHT97881.1 - 0.00058 19.7 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 EHT97881.1 - 0.0039 17.4 0.0 0.037 14.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EHT97881.1 - 0.0056 16.0 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin MeaB PF03308.16 EHT97881.1 - 0.016 14.2 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 EHT97881.1 - 0.03 14.6 0.0 0.069 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 EHT97881.1 - 0.031 13.7 0.0 0.083 12.3 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 T2SSE PF00437.20 EHT97881.1 - 0.045 12.8 0.0 0.075 12.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 EHT97881.1 - 0.12 12.0 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EHT97881.1 - 0.17 11.4 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Pex14_N PF04695.13 EHT97881.1 - 3.9 8.1 7.6 2.1 9.0 2.6 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TrwC PF08751.11 EHT97882.1 - 3.2e-68 230.4 0.9 7.5e-68 229.2 0.0 2.0 2 1 0 2 2 2 1 TrwC relaxase TraI_2B PF18340.1 EHT97882.1 - 5.7e-25 87.2 0.5 5.7e-25 87.2 0.5 2.3 2 0 0 2 2 2 1 DNA relaxase TraI 2B/2B-like domain ssDNA_TraI_N PF18272.1 EHT97882.1 - 5.9e-13 48.6 2.7 5.9e-13 48.6 2.7 2.7 3 0 0 3 3 3 1 single-stranded DNA binding TraI N-terminal subdomain DUF4129 PF13559.6 EHT97882.1 - 0.97 9.7 5.9 0.91 9.8 2.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) AAA_30 PF13604.6 EHT97883.1 - 2.9e-32 111.9 1.2 2.9e-32 111.9 1.2 3.0 4 0 0 4 4 4 1 AAA domain TraI PF07057.11 EHT97883.1 - 1.5e-28 99.4 1.6 4.7e-28 97.8 0.2 2.4 2 0 0 2 2 2 1 DNA helicase TraI AAA_19 PF13245.6 EHT97883.1 - 3e-11 43.9 1.5 1e-10 42.1 0.1 2.3 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 EHT97883.1 - 0.00024 20.9 0.5 0.00072 19.3 0.5 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF2058 PF09831.9 EHT97883.1 - 6 7.0 14.8 18 5.5 14.8 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Thioredoxin_4 PF13462.6 EHT97885.1 - 4.7e-18 65.9 1.1 2.9e-17 63.3 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin ScsC_N PF18312.1 EHT97885.1 - 1.4e-14 53.6 4.9 5.9e-14 51.6 4.9 2.2 1 1 0 1 1 1 1 Copper resistance protein ScsC N-terminal domain DSBA PF01323.20 EHT97885.1 - 8.4e-13 48.5 5.4 4.6e-12 46.1 2.1 2.6 2 1 0 2 2 2 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 EHT97885.1 - 8.7e-11 42.2 1.7 3.3e-09 37.2 0.2 2.9 1 1 1 2 2 2 1 Thioredoxin-like domain Thioredoxin PF00085.20 EHT97885.1 - 0.00081 19.3 0.1 0.02 14.9 0.1 2.4 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 EHT97885.1 - 0.01 16.2 0.1 2.5 8.5 0.1 2.6 3 0 0 3 3 3 0 Thioredoxin-like DUF2946 PF11162.8 EHT97885.1 - 0.072 13.8 0.2 0.22 12.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) PLDc_2 PF13091.6 EHT97886.1 - 6.2e-27 94.1 0.3 7.3e-27 93.9 0.3 1.1 1 0 0 1 1 1 1 PLD-like domain FAM83 PF07894.12 EHT97886.1 - 3e-05 23.7 0.1 0.0018 17.9 0.1 2.0 1 1 0 1 1 1 1 FAM83 A-H Regulator_TrmB PF11495.8 EHT97886.1 - 0.00092 18.5 0.0 0.001 18.3 0.0 1.1 1 0 0 1 1 1 1 Archaeal transcriptional regulator TrmB CmcI PF04989.12 EHT97886.1 - 0.027 14.2 0.3 0.037 13.7 0.3 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase RepB-RCR_reg PF10723.9 EHT97887.1 - 6.6e-38 128.5 0.9 7.9e-38 128.3 0.9 1.0 1 0 0 1 1 1 1 Replication regulatory protein RepB IncFII_repA PF02387.15 EHT97888.1 - 5.8e-30 104.5 0.1 7.8e-30 104.0 0.1 1.1 1 0 0 1 1 1 1 IncFII RepA protein family DEDD_Tnp_IS110 PF01548.17 EHT97889.1 - 2.1e-25 89.4 0.0 3.5e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 Transposase Transposase_20 PF02371.16 EHT97889.1 - 6.5e-18 64.8 0.0 1.2e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family TSP_C PF05735.12 EHT97890.1 - 0.21 11.5 0.0 0.32 10.9 0.0 1.2 1 0 0 1 1 1 0 Thrombospondin C-terminal region Zn_Tnp_IS91 PF14319.6 EHT97891.1 - 2.3e-17 62.8 11.5 2.8e-17 62.5 11.5 1.1 1 0 0 1 1 1 1 Transposase zinc-binding domain zf-piccolo PF05715.13 EHT97891.1 - 0.052 13.7 9.5 0.08 13.1 9.5 1.4 1 1 0 1 1 1 0 Piccolo Zn-finger zf-B_box PF00643.24 EHT97891.1 - 0.16 12.1 9.4 0.26 11.5 9.4 1.4 1 0 0 1 1 1 0 B-box zinc finger DUF5585 PF17823.1 EHT97892.1 - 0.099 11.6 7.1 0.14 11.1 7.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5585) HTH_Tnp_1 PF01527.20 EHT97893.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT97893.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT97893.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT97893.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHT97894.1 - 1.7e-39 133.8 0.0 2e-39 133.6 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHT97895.1 - 2.7e-97 325.6 3.4 1.2e-96 323.5 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT97895.1 - 3.4e-16 59.1 0.1 1.3e-15 57.3 0.1 2.1 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT97895.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT97895.1 - 1.2e-11 45.2 9.0 2.6e-11 44.1 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Exonuc_VII_L PF02601.15 EHT97895.1 - 0.042 13.4 2.1 0.052 13.1 0.7 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit FUSC PF04632.12 EHT97895.1 - 0.049 12.2 7.0 0.078 11.5 7.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Phage_HK97_TLTM PF06120.11 EHT97895.1 - 0.054 12.7 1.5 0.11 11.7 1.5 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHT97895.1 - 0.15 12.4 3.6 0.93 9.9 0.3 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain UME PF08064.13 EHT97895.1 - 0.15 12.0 0.4 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain FAM184 PF15665.5 EHT97895.1 - 0.16 11.7 5.7 0.25 11.1 5.7 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B DHR10 PF18595.1 EHT97895.1 - 0.18 11.9 10.2 0.31 11.1 10.2 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Tho2 PF11262.8 EHT97895.1 - 0.2 10.9 0.3 0.32 10.2 0.3 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 LXG PF04740.12 EHT97895.1 - 0.21 11.3 2.2 0.8 9.4 0.3 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHT97895.1 - 0.23 11.2 10.2 0.38 10.5 10.2 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HHH_8 PF14716.6 EHT97895.1 - 0.28 11.6 3.7 0.55 10.6 1.8 2.4 2 1 0 2 2 2 0 Helix-hairpin-helix domain Zn-ribbon_8 PF09723.10 EHT97895.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain TSNAXIP1_N PF15739.5 EHT97895.1 - 0.47 10.9 3.2 0.99 9.8 3.2 1.5 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus TMPIT PF07851.13 EHT97895.1 - 1 8.5 2.7 1.6 7.9 2.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHT97895.1 - 3.6 7.1 7.2 9.3 5.7 7.2 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 SlyX PF04102.12 EHT97895.1 - 8.2 7.1 8.7 12 6.6 1.6 3.0 1 1 1 2 2 2 0 SlyX DEDD_Tnp_IS110 PF01548.17 EHT97896.1 - 1.1e-25 90.3 0.0 1.8e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Transposase Transposase_20 PF02371.16 EHT97896.1 - 9.7e-10 38.6 0.0 1.7e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family SF3A3 PF16837.5 EHT97897.1 - 0.082 13.4 1.0 0.17 12.4 1.0 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 CcdA PF07362.12 EHT97898.1 - 3.2e-25 88.3 1.4 3.4e-25 88.2 1.4 1.0 1 0 0 1 1 1 1 Post-segregation antitoxin CcdA CcdB PF01845.17 EHT97899.1 - 3e-29 101.2 0.0 3.3e-29 101.0 0.0 1.0 1 0 0 1 1 1 1 CcdB protein DUF4956 PF16316.5 EHT97900.1 - 0.022 14.4 0.4 0.022 14.4 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4956) DUF1460 PF07313.12 EHT97901.1 - 8.4e-76 254.1 0.0 1.1e-75 253.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1460) N_NLPC_P60 PF12912.7 EHT97902.1 - 0.0097 16.3 0.0 0.0097 16.3 0.0 1.1 1 0 0 1 1 1 1 NLPC_P60 stabilising domain, N term DDE_Tnp_IS66 PF03050.14 EHT97903.1 - 8.6e-98 327.3 4.1 3.2e-97 325.4 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT97903.1 - 3.1e-16 59.3 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT97903.1 - 8.1e-15 54.9 1.3 1.9e-14 53.8 1.3 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT97903.1 - 1.7e-11 44.8 9.6 3.5e-11 43.7 9.6 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHT97903.1 - 0.017 14.9 6.4 0.027 14.3 6.4 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Phage_HK97_TLTM PF06120.11 EHT97903.1 - 0.022 14.0 1.7 0.042 13.0 1.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHT97903.1 - 0.022 15.1 4.3 0.091 13.1 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Exonuc_VII_L PF02601.15 EHT97903.1 - 0.029 14.0 1.8 0.039 13.5 0.6 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit FUSC PF04632.12 EHT97903.1 - 0.036 12.6 6.9 0.056 12.0 6.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tho2 PF11262.8 EHT97903.1 - 0.057 12.6 0.5 0.094 11.9 0.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Troponin PF00992.20 EHT97903.1 - 0.062 13.6 3.0 0.11 12.8 3.0 1.3 1 0 0 1 1 1 0 Troponin LXG PF04740.12 EHT97903.1 - 0.11 12.2 2.6 0.33 10.6 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHT97903.1 - 0.16 11.8 10.8 0.26 11.1 10.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family UME PF08064.13 EHT97903.1 - 0.16 11.9 0.5 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain HalX PF08663.10 EHT97903.1 - 0.23 11.8 3.1 0.59 10.5 3.1 1.7 1 0 0 1 1 1 0 HalX domain DHR10 PF18595.1 EHT97903.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF1192 PF06698.11 EHT97903.1 - 0.47 10.5 5.3 3.4 7.8 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHT97903.1 - 1.1 8.4 3.1 1.7 7.8 3.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHT97903.1 - 2.8 7.4 7.9 6.1 6.3 7.9 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHT97903.1 - 3.3 8.1 7.9 6.7 7.0 7.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 EHT97903.1 - 7.2 7.3 8.7 7.7 7.2 1.0 3.0 1 1 1 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHT97904.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHT97905.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT97905.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT97905.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT97905.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix HHA PF05321.11 EHT97907.1 - 1.1e-28 99.4 0.2 1.2e-28 99.2 0.2 1.0 1 0 0 1 1 1 1 Haemolysin expression modulating protein HTH_Tnp_1 PF01527.20 EHT97908.1 - 2e-11 44.1 0.1 2.2e-11 43.9 0.1 1.1 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 EHT97908.1 - 3.9e-06 26.9 0.1 4.4e-06 26.7 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 EHT97908.1 - 7.5e-06 25.6 0.1 8.7e-06 25.4 0.1 1.1 1 0 0 1 1 1 1 Homeodomain-like domain CENP-B_N PF04218.13 EHT97908.1 - 0.00033 20.2 0.0 0.00038 20.0 0.0 1.1 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain Terminase_5 PF06056.12 EHT97908.1 - 0.00037 20.3 0.1 0.00051 19.9 0.1 1.2 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) HTH_7 PF02796.15 EHT97908.1 - 0.00074 19.5 0.0 0.00095 19.2 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_Tnp_ISL3 PF13542.6 EHT97908.1 - 0.0076 15.7 0.0 0.0088 15.4 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 GP3_package PF16677.5 EHT97908.1 - 0.087 13.0 0.0 0.088 13.0 0.0 1.0 1 0 0 1 1 1 0 DNA-packaging protein gp3 MerR_1 PF13411.6 EHT97908.1 - 0.098 12.8 0.2 0.77 9.9 0.1 1.9 2 0 0 2 2 2 0 MerR HTH family regulatory protein HTH_22 PF13309.6 EHT97908.1 - 0.1 12.7 0.4 0.24 11.5 0.4 1.7 1 1 0 1 1 1 0 HTH domain HTH_29 PF13551.6 EHT97908.1 - 0.16 12.0 0.1 0.19 11.8 0.1 1.1 1 0 0 1 1 1 0 Winged helix-turn helix Cellulase PF00150.18 EHT97909.1 - 2.6e-54 184.6 8.8 3.3e-54 184.2 8.8 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Secretin PF00263.21 EHT97910.1 - 1e-47 161.9 2.1 1e-47 161.9 2.1 2.1 2 1 1 3 3 3 1 Bacterial type II and III secretion system protein Secretin_N PF03958.17 EHT97910.1 - 2.8e-31 107.8 18.6 3.3e-14 53.0 6.1 4.4 3 1 0 3 3 3 3 Bacterial type II/III secretion system short domain T2SSE PF00437.20 EHT97911.1 - 6.7e-86 287.7 2.7 9.4e-86 287.2 2.7 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_23 PF13476.6 EHT97911.1 - 2.6e-05 24.8 0.0 4.1e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EHT97911.1 - 4.6e-05 23.1 0.0 0.00012 21.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EHT97911.1 - 0.00016 22.0 0.0 0.0021 18.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EHT97911.1 - 0.00046 20.6 0.0 0.0013 19.2 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 EHT97911.1 - 0.002 17.9 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 EHT97911.1 - 0.0034 17.3 0.4 0.14 12.1 0.1 2.3 1 1 0 2 2 2 1 NTPase AAA PF00004.29 EHT97911.1 - 0.0045 17.4 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EHT97911.1 - 0.0045 17.5 0.0 0.012 16.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter Rad17 PF03215.15 EHT97911.1 - 0.0046 16.9 0.0 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_11 PF13086.6 EHT97911.1 - 0.0068 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EHT97911.1 - 0.007 16.3 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EHT97911.1 - 0.0073 16.3 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EHT97911.1 - 0.018 15.4 0.0 0.053 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EHT97911.1 - 0.021 14.2 0.3 0.058 12.7 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_5 PF07728.14 EHT97911.1 - 0.032 14.2 0.0 0.07 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EHT97911.1 - 0.032 13.8 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 EHT97911.1 - 0.07 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_27 PF13514.6 EHT97911.1 - 0.19 11.3 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 EHT97911.1 - 0.22 11.5 0.0 0.41 10.6 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_21 PF13304.6 EHT97911.1 - 0.23 11.2 0.0 0.33 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system T2SSF PF00482.23 EHT97912.1 - 9.3e-50 167.8 19.0 8.8e-29 100.0 2.8 2.6 3 0 0 3 3 3 2 Type II secretion system (T2SS), protein F T2SSG PF08334.11 EHT97913.1 - 3e-39 133.4 0.7 3.6e-39 133.2 0.7 1.1 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein G N_methyl PF07963.12 EHT97913.1 - 3.8e-09 35.7 3.9 5.3e-09 35.3 3.9 1.2 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif ComP_DUS PF16732.5 EHT97913.1 - 0.032 15.1 0.0 0.047 14.6 0.0 1.3 1 0 0 1 1 1 0 Type IV minor pilin ComP, DNA uptake sequence receptor T2SSI PF02501.17 EHT97914.1 - 2.1e-16 59.8 0.2 2.9e-16 59.4 0.2 1.2 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein I N_methyl PF07963.12 EHT97914.1 - 0.0041 16.6 1.8 0.0068 15.9 1.8 1.4 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif T2SSJ PF11612.8 EHT97915.1 - 2.2e-17 63.6 1.6 3.1e-17 63.1 1.6 1.2 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein J N_methyl PF07963.12 EHT97915.1 - 2.6e-09 36.2 0.3 4.7e-09 35.4 0.3 1.4 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif Astro_capsid_p PF12226.8 EHT97915.1 - 0.064 12.4 0.4 0.095 11.8 0.1 1.5 2 0 0 2 2 2 0 Turkey astrovirus capsid protein T2SSK PF03934.13 EHT97916.1 - 1.2e-24 87.2 4.0 3.6e-13 49.5 2.3 2.0 1 1 1 2 2 2 2 Type II secretion system (T2SS), protein K FtsL PF04999.13 EHT97916.1 - 0.0036 17.3 0.8 0.0067 16.4 0.8 1.4 1 0 0 1 1 1 1 Cell division protein FtsL MNSV_P7B PF06692.11 EHT97916.1 - 0.083 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Melon necrotic spot virus P7B protein T2SSL PF05134.13 EHT97917.1 - 7e-18 64.8 0.2 1.5e-17 63.7 0.2 1.5 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein L GspL_C PF12693.7 EHT97917.1 - 0.018 14.9 5.4 0.032 14.1 5.4 1.4 1 0 0 1 1 1 0 GspL periplasmic domain CDC45 PF02724.14 EHT97917.1 - 0.069 11.4 0.1 0.1 10.9 0.1 1.2 1 0 0 1 1 1 0 CDC45-like protein NAD_binding_11 PF14833.6 EHT97917.1 - 0.31 11.3 4.2 13 6.1 0.0 3.2 3 0 0 3 3 3 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase T2SSM PF04612.12 EHT97918.1 - 4.1e-16 59.4 7.2 6.5e-16 58.8 7.2 1.4 1 1 0 1 1 1 1 Type II secretion system (T2SS), protein M BPD_transp_2 PF02653.16 EHT97918.1 - 0.034 13.3 0.8 0.04 13.1 0.8 1.3 1 1 0 1 1 1 0 Branched-chain amino acid transport system / permease component DiS_P_DiS PF06750.13 EHT97919.1 - 2.4e-22 78.8 0.4 4.9e-22 77.8 0.4 1.5 1 0 0 1 1 1 1 Bacterial Peptidase A24 N-terminal domain Peptidase_A24 PF01478.18 EHT97919.1 - 1.4e-19 70.4 13.2 2.3e-19 69.8 13.2 1.3 1 0 0 1 1 1 1 Type IV leader peptidase family T2SS_PulS_OutS PF09691.10 EHT97920.1 - 4.3e-20 71.9 0.0 4.9e-20 71.7 0.0 1.0 1 0 0 1 1 1 1 Type II secretion system pilotin lipoprotein (PulS_OutS) DDE_Tnp_IS240 PF13610.6 EHT97921.1 - 0.0013 19.0 0.0 0.0015 18.8 0.0 1.1 1 0 0 1 1 1 1 DDE domain AAA_31 PF13614.6 EHT97924.1 - 1.2e-23 83.9 0.2 3.2e-16 59.7 0.1 2.0 1 1 1 2 2 2 2 AAA domain CbiA PF01656.23 EHT97924.1 - 1.1e-15 57.8 0.0 1.2e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 EHT97924.1 - 2.7e-10 40.1 0.3 1.6e-09 37.6 0.1 1.9 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase MipZ PF09140.11 EHT97924.1 - 1.1e-08 34.7 0.9 3.5e-05 23.2 0.1 2.2 1 1 0 2 2 2 2 ATPase MipZ ArsA_ATPase PF02374.15 EHT97924.1 - 6.2e-08 32.2 0.2 1.2e-07 31.2 0.0 1.5 2 0 0 2 2 2 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 EHT97924.1 - 8.2e-06 25.5 0.2 0.0034 16.9 0.3 2.1 1 1 0 2 2 2 2 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 EHT97924.1 - 6.5e-05 22.5 0.0 0.00014 21.4 0.0 1.4 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.11 EHT97924.1 - 0.00013 21.3 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 VirC1 protein CLP1_P PF16575.5 EHT97924.1 - 0.008 16.0 0.0 0.017 14.9 0.0 1.5 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_25 PF13481.6 EHT97924.1 - 0.11 12.1 0.2 0.13 11.8 0.2 1.4 1 1 0 1 1 1 0 AAA domain Transposase_mut PF00872.18 EHT97925.1 - 6.6e-110 367.5 0.0 7.4e-110 367.4 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 EHT97925.1 - 7.9e-07 29.4 0.0 2.8e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 MULE transposase domain DUF433 PF04255.14 EHT97925.1 - 0.0029 17.4 0.0 0.0061 16.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF433) DDE_Tnp_IS240 PF13610.6 EHT97925.1 - 0.032 14.5 0.0 2.2 8.5 0.0 2.6 2 1 0 2 2 2 0 DDE domain HTH_23 PF13384.6 EHT97925.1 - 0.082 12.7 0.2 0.56 10.1 0.0 2.5 3 0 0 3 3 3 0 Homeodomain-like domain HTH_38 PF13936.6 EHT97925.1 - 0.14 11.9 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain DDE_3 PF13358.6 EHT97927.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHT97927.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHT97927.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHT97927.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHT97927.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHT97927.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHT97927.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHT97927.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 rve PF00665.26 EHT97928.1 - 1.6e-20 73.4 0.0 3.1e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain HTH_29 PF13551.6 EHT97928.1 - 1.2e-18 66.9 0.1 2.2e-18 66.0 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn helix rve_3 PF13683.6 EHT97928.1 - 9.1e-11 41.4 0.0 2.3e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain HTH_28 PF13518.6 EHT97928.1 - 3.9e-06 26.9 0.0 9.6e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 EHT97928.1 - 5.6e-05 22.8 0.2 0.00026 20.7 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.15 EHT97928.1 - 0.0053 16.8 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_8 PF02954.19 EHT97928.1 - 0.0096 15.7 0.0 0.025 14.3 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family HTH_32 PF13565.6 EHT97928.1 - 0.012 16.2 0.1 0.052 14.2 0.0 2.1 2 1 0 2 2 2 0 Homeodomain-like domain rve_2 PF13333.6 EHT97928.1 - 0.018 15.2 0.0 0.042 14.0 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain HTH_22 PF13309.6 EHT97928.1 - 0.11 12.5 0.0 0.39 10.8 0.0 1.9 2 0 0 2 2 2 0 HTH domain HTH_17 PF12728.7 EHT97928.1 - 0.22 11.8 1.0 0.58 10.4 0.0 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain DDE_Tnp_IS240 PF13610.6 EHT97929.1 - 1.7e-29 102.9 0.0 2.9e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 DDE domain DDE_Tnp_IS66 PF03050.14 EHT97929.1 - 2.1e-09 37.3 0.2 2.1e-09 37.3 0.2 1.1 1 0 0 1 1 1 1 Transposase IS66 family rve PF00665.26 EHT97929.1 - 2.4e-07 31.0 0.3 5.8e-07 29.7 0.1 1.7 2 0 0 2 2 2 1 Integrase core domain DUF859 PF05895.12 EHT97930.1 - 0.14 10.6 0.0 0.17 10.3 0.0 1.0 1 0 0 1 1 1 0 Siphovirus protein of unknown function (DUF859) Transposase_31 PF04754.12 EHT97931.1 - 3.6e-82 274.9 0.0 4.7e-82 274.5 0.0 1.1 1 0 0 1 1 1 1 Putative transposase, YhgA-like Yae1_N PF09811.9 EHT97931.1 - 0.0095 15.6 6.8 0.016 14.9 6.8 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal LPD23 PF18838.1 EHT97931.1 - 0.07 12.9 0.8 0.16 11.7 0.1 2.0 2 0 0 2 2 2 0 Large polyvalent protein associated domain 23 Resolvase PF00239.21 EHT97932.1 - 8.3e-23 81.1 0.7 1.5e-22 80.3 0.7 1.4 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_7 PF02796.15 EHT97932.1 - 2.1e-09 37.3 0.0 4.5e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_38 PF13936.6 EHT97932.1 - 7e-07 28.9 0.2 2.2e-06 27.3 0.1 1.9 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 EHT97932.1 - 3.3e-06 26.4 0.2 8.5e-06 25.1 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.6 EHT97932.1 - 5.6e-06 26.4 1.0 9.7e-06 25.6 0.2 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 EHT97932.1 - 2e-05 24.2 0.6 6.6e-05 22.6 0.1 2.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.6 EHT97932.1 - 0.00038 20.4 3.4 0.00049 20.1 0.1 2.5 2 1 1 3 3 3 1 Winged helix-turn helix UxuA PF03786.13 EHT97932.1 - 0.00048 19.1 0.0 0.00059 18.8 0.0 1.0 1 0 0 1 1 1 1 D-mannonate dehydratase (UxuA) HTH_22 PF13309.6 EHT97932.1 - 0.0012 18.9 0.2 0.18 11.9 0.1 3.0 2 1 0 2 2 2 1 HTH domain HTH_Tnp_1 PF01527.20 EHT97932.1 - 0.0043 17.3 0.0 0.0098 16.2 0.0 1.5 1 0 0 1 1 1 1 Transposase HTH_50 PF18024.1 EHT97932.1 - 0.1 12.3 0.2 4.2 7.0 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_DeoR PF08220.12 EHT97932.1 - 0.13 12.0 0.5 12 5.7 0.0 3.0 3 0 0 3 3 3 0 DeoR-like helix-turn-helix domain Gp49 PF05973.14 EHT97934.1 - 2e-24 85.5 0.0 2.2e-24 85.4 0.0 1.0 1 0 0 1 1 1 1 Phage derived protein Gp49-like (DUF891) ParE_toxin PF05016.15 EHT97934.1 - 0.18 12.4 0.0 0.28 11.8 0.0 1.3 1 0 0 1 1 1 0 ParE toxin of type II toxin-antitoxin system, parDE HTH_3 PF01381.22 EHT97935.1 - 7e-12 45.2 0.0 1.2e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EHT97935.1 - 6.8e-10 39.1 0.4 9.8e-10 38.6 0.4 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 EHT97935.1 - 2.5e-07 30.5 0.1 3.6e-07 30.0 0.1 1.3 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 EHT97935.1 - 3.2e-07 30.3 0.0 6.1e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 EHT97935.1 - 0.0015 18.2 0.1 0.0083 15.9 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 EHT97935.1 - 0.0018 18.0 0.1 0.0098 15.7 0.0 2.0 1 1 1 2 2 2 1 Homeodomain-like domain HTH_26 PF13443.6 EHT97935.1 - 0.0027 18.1 0.0 0.0047 17.3 0.0 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 EHT97935.1 - 0.0069 16.2 0.0 0.022 14.6 0.0 1.9 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 EHT97935.1 - 0.0075 16.6 0.2 0.68 10.3 0.1 2.6 1 1 2 3 3 3 1 Transposase MarR_2 PF12802.7 EHT97935.1 - 0.017 15.0 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.6 EHT97935.1 - 0.037 13.6 0.0 0.073 12.6 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding AbiEi_4 PF13338.6 EHT97935.1 - 0.038 14.1 0.1 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin TetR_N PF00440.23 EHT97935.1 - 0.085 12.7 0.1 14 5.5 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family Fe_dep_repress PF01325.19 EHT97935.1 - 0.11 12.7 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain MerR PF00376.23 EHT97935.1 - 0.13 12.1 0.0 5.4 6.9 0.0 2.4 2 0 0 2 2 2 0 MerR family regulatory protein MinE PF03776.14 EHT97935.1 - 0.25 11.4 1.0 1.2 9.2 0.2 2.3 2 1 0 2 2 2 0 Septum formation topological specificity factor MinE Bac_export_2 PF01312.19 EHT97936.1 - 2.9e-94 316.0 3.2 3.2e-94 315.8 3.2 1.0 1 0 0 1 1 1 1 FlhB HrpN YscU SpaS Family Bac_export_1 PF01311.20 EHT97937.1 - 2e-49 168.2 24.1 2.3e-49 168.1 24.1 1.0 1 0 0 1 1 1 1 Bacterial export proteins, family 1 Bac_export_3 PF01313.19 EHT97938.1 - 2.8e-24 84.8 12.3 3.2e-24 84.7 12.3 1.0 1 0 0 1 1 1 1 Bacterial export proteins, family 3 Cellulose_synt PF03552.14 EHT97938.1 - 0.22 10.0 3.9 0.24 9.9 3.9 1.0 1 0 0 1 1 1 0 Cellulose synthase DUF3810 PF12725.7 EHT97938.1 - 0.48 9.7 3.3 0.49 9.7 3.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) SLATT_5 PF18160.1 EHT97938.1 - 0.75 9.1 4.0 0.7 9.2 3.2 1.3 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Bac_export_2 PF01312.19 EHT97938.1 - 0.8 8.8 8.0 0.45 9.7 5.2 1.7 1 1 1 2 2 2 0 FlhB HrpN YscU SpaS Family UPF0182 PF03699.13 EHT97938.1 - 1.5 6.8 6.0 1.6 6.7 6.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) FliP PF00813.20 EHT97939.1 - 3.8e-63 212.8 6.1 4.5e-63 212.6 6.1 1.0 1 0 0 1 1 1 1 FliP family FliMN_C PF01052.20 EHT97940.1 - 1.6e-12 47.2 0.1 5.1e-12 45.6 0.1 1.7 2 0 0 2 2 2 1 Type III flagellar switch regulator (C-ring) FliN C-term SepQ PF06622.11 EHT97940.1 - 0.2 10.7 0.0 6.7 5.7 0.0 2.1 2 0 0 2 2 2 0 SepQ protein RNA_pol_Rpb2_3 PF04565.16 EHT97941.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 3 TBCA PF02970.16 EHT97942.1 - 0.15 12.4 7.4 2 8.8 1.6 2.3 1 1 1 2 2 2 0 Tubulin binding cofactor A Csm1_N PF18504.1 EHT97942.1 - 9.8 6.6 10.4 6.5 7.2 3.1 2.2 2 0 0 2 2 2 0 Csm1 N-terminal domain ATP-synt_ab PF00006.25 EHT97943.1 - 4.4e-71 238.9 0.0 5.4e-71 238.6 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain T3SS_ATPase_C PF18269.1 EHT97943.1 - 1.3e-22 79.4 0.1 2.3e-22 78.6 0.1 1.4 1 0 0 1 1 1 1 T3SS EscN ATPase C-terminal domain DUF87 PF01935.17 EHT97943.1 - 0.0045 17.1 0.0 0.0079 16.3 0.0 1.3 1 0 0 1 1 1 1 Helicase HerA, central domain ABC_tran PF00005.27 EHT97943.1 - 0.015 15.8 0.0 0.028 14.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter ATP-synt_ab_N PF02874.23 EHT97943.1 - 0.051 14.1 0.0 0.14 12.7 0.0 1.8 1 0 0 1 1 1 0 ATP synthase alpha/beta family, beta-barrel domain AAA_22 PF13401.6 EHT97943.1 - 0.052 13.8 0.0 0.17 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 EHT97943.1 - 0.13 11.2 0.1 0.29 10.1 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FHIPEP PF00771.20 EHT97944.1 - 1.1e-209 698.2 5.2 1.5e-209 697.8 5.2 1.1 1 0 0 1 1 1 1 FHIPEP family FA_desaturase PF00487.24 EHT97944.1 - 0.6 9.9 0.0 0.6 9.9 0.0 2.3 2 1 0 2 2 2 0 Fatty acid desaturase DUF3583 PF12126.8 EHT97944.1 - 1.4 8.3 4.3 1.6 8.1 3.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3583) HrpJ PF07201.11 EHT97946.1 - 4e-07 30.5 13.3 5.7e-07 30.0 9.5 2.8 2 1 0 2 2 2 1 HrpJ-like domain TyeA PF09059.10 EHT97946.1 - 0.00062 19.8 0.1 0.00062 19.8 0.1 2.2 2 0 0 2 2 2 1 TyeA Cas9-BH PF16593.5 EHT97946.1 - 0.044 13.5 0.4 0.044 13.5 0.4 2.3 2 0 0 2 2 2 0 Bridge helix of CRISPR-associated endonuclease Cas9 DUF5071 PF16804.5 EHT97946.1 - 0.053 13.8 0.0 0.18 12.0 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5071) MarR_2 PF12802.7 EHT97946.1 - 0.098 12.6 0.7 0.38 10.7 0.2 2.3 2 0 0 2 2 2 0 MarR family HrpE PF06188.12 EHT97947.1 - 0.024 14.5 5.9 0.82 9.5 5.8 2.1 1 1 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E T3SS_LEE_assoc PF13327.6 EHT97948.1 - 1.2e-25 90.5 0.8 1.4e-25 90.2 0.8 1.1 1 0 0 1 1 1 1 Type III secretion system subunit YscJ_FliF PF01514.17 EHT97949.1 - 3.9e-22 78.9 0.0 6.1e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Secretory protein of YscJ/FliF family T3SS_basalb_I PF17001.5 EHT97950.1 - 3.6e-06 27.5 0.6 5.2e-06 27.0 0.6 1.4 1 1 0 1 1 1 1 Type III secretion basal body protein I, YscI, HrpB, PscI DUF1039 PF06287.11 EHT97951.1 - 7e-22 77.6 0.8 7.6e-22 77.5 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1039) T3SS_needle_F PF09392.10 EHT97952.1 - 5.2e-24 84.2 1.5 5.7e-24 84.1 1.5 1.0 1 0 0 1 1 1 1 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF TPR_19 PF14559.6 EHT97955.1 - 2.7e-08 34.2 0.1 5.3e-08 33.3 0.0 1.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EHT97955.1 - 1.6e-07 30.9 0.5 0.012 15.7 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EHT97955.1 - 3.3e-06 26.7 1.6 0.015 15.1 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 EHT97955.1 - 0.00013 22.0 0.1 0.00016 21.7 0.1 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EHT97955.1 - 0.00045 20.4 0.1 0.00057 20.1 0.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EHT97955.1 - 0.011 16.4 1.2 0.02 15.5 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EHT97955.1 - 0.014 15.7 0.2 0.32 11.3 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EHT97955.1 - 0.015 16.0 0.2 1.1 10.3 0.0 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EHT97955.1 - 0.037 14.2 0.9 0.088 13.1 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.12 EHT97955.1 - 0.042 13.9 0.4 5.5 7.1 0.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EHT97956.1 - 0.0009 19.0 0.1 0.015 15.1 0.1 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EHT97956.1 - 0.0038 17.2 1.2 0.015 15.3 0.7 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EHT97956.1 - 0.053 14.2 0.3 0.095 13.4 0.4 1.4 2 0 0 2 2 2 0 Tetratricopeptide repeat P68HR PF08061.11 EHT97956.1 - 0.13 12.4 0.2 0.17 12.0 0.2 1.1 1 0 0 1 1 1 0 P68HR (NUC004) repeat EspB PF05802.11 EHT97958.1 - 5.8e-23 81.9 4.6 1.4e-11 44.8 0.4 2.1 1 1 1 2 2 2 2 Enterobacterial EspB protein KELK PF15796.5 EHT97958.1 - 0.12 12.8 1.4 0.67 10.4 0.3 2.1 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase SseC PF04888.12 EHT97959.1 - 7.8e-52 176.8 43.1 1.1e-50 173.0 43.1 1.9 1 1 0 1 1 1 1 Secretion system effector C (SseC) like family Ribosomal_S8 PF00410.19 EHT97959.1 - 0.019 14.9 0.2 0.073 13.0 0.2 2.0 1 0 0 1 1 1 0 Ribosomal protein S8 Alpha-E PF04168.12 EHT97959.1 - 0.03 14.1 0.1 0.088 12.6 0.1 1.7 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. Ribosomal_L5 PF00281.19 EHT97959.1 - 0.2 12.0 2.4 16 5.9 0.0 3.4 3 0 0 3 3 3 0 Ribosomal protein L5 IcmF-related PF06761.12 EHT97959.1 - 0.26 10.7 2.8 0.94 8.9 0.0 2.7 3 1 0 4 4 4 0 Intracellular multiplication and human macrophage-killing DUF2564 PF10819.8 EHT97959.1 - 2.8 8.4 12.8 7.1 7.1 2.1 3.8 3 1 2 5 5 5 0 Protein of unknown function (DUF2564) Anti-adapt_IraP PF10796.9 EHT97959.1 - 3 8.5 7.8 32 5.2 0.3 4.0 2 2 1 3 3 3 0 Sigma-S stabilisation anti-adaptor protein TPR_2 PF07719.17 EHT97960.1 - 0.00073 19.5 13.6 0.044 13.9 0.3 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EHT97960.1 - 0.0065 16.7 3.5 0.28 11.5 0.1 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EHT97960.1 - 0.0085 15.9 7.5 0.12 12.2 0.6 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EHT97960.1 - 0.026 15.1 8.7 3.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EHT97960.1 - 0.086 13.7 7.5 1.4 9.9 0.9 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.12 EHT97960.1 - 0.097 12.7 4.3 0.25 11.4 0.1 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EHT97960.1 - 1 9.5 3.3 13 6.1 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat EspA PF03433.13 EHT97961.1 - 1.6e-52 178.0 3.3 1.9e-52 177.7 3.3 1.0 1 0 0 1 1 1 1 EspA-like secreted protein DUF948 PF06103.11 EHT97961.1 - 0.03 14.6 1.3 0.24 11.7 0.3 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Fil_haemagg PF05594.14 EHT97961.1 - 7.7 7.1 11.9 1.1 9.9 1.8 2.8 2 1 1 3 3 3 0 Haemagluttinin repeat T3SchapCesA PF11439.8 EHT97962.1 - 0.11 12.6 0.0 0.17 12.1 0.0 1.2 1 1 0 1 1 1 0 Type III secretion system filament chaperone CesA T3SS_needle_E PF08988.10 EHT97963.1 - 9.3e-10 38.5 0.6 1e-09 38.4 0.6 1.1 1 0 0 1 1 1 1 Type III secretion system, cytoplasmic E component of needle Yop-YscD_ppl PF16693.5 EHT97964.1 - 5.7e-14 52.2 0.1 6.9e-14 51.9 0.1 1.0 1 0 0 1 1 1 1 Inner membrane component of T3SS, periplasmic domain Secretin PF00263.21 EHT97965.1 - 8.5e-33 113.4 2.6 1.6e-32 112.5 2.6 1.5 1 0 0 1 1 1 1 Bacterial type II and III secretion system protein Secretin_N PF03958.17 EHT97965.1 - 8.6e-18 64.5 0.0 8.1e-15 55.0 0.1 2.8 2 0 0 2 2 2 2 Bacterial type II/III secretion system short domain Response_reg PF00072.24 EHT97967.1 - 1.9e-22 79.5 0.0 4.1e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 EHT97967.1 - 5.4e-22 78.4 0.0 1.4e-21 77.1 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EHT97967.1 - 4e-15 55.6 0.4 4e-15 55.6 0.4 2.3 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 EHT97967.1 - 4.2e-07 30.2 0.0 1.3e-06 28.7 0.0 1.9 1 0 0 1 1 1 1 HAMP domain Hpt PF01627.23 EHT97967.1 - 0.026 14.8 2.3 0.037 14.3 0.4 2.4 2 1 0 2 2 2 0 Hpt domain Response_reg PF00072.24 EHT97968.1 - 3.7e-24 85.0 0.0 6.9e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 EHT97968.1 - 1.1e-19 69.7 0.2 1.8e-19 69.0 0.2 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 EHT97968.1 - 0.0001 21.9 0.1 0.00026 20.6 0.1 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EHT97968.1 - 0.012 15.1 0.3 0.031 13.8 0.3 1.7 1 1 0 1 1 1 0 Sigma-70, region 4 HTH_38 PF13936.6 EHT97968.1 - 0.018 14.8 0.1 0.041 13.7 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain DNA_ligase_aden PF01653.18 EHT97969.1 - 0.015 14.4 0.2 0.033 13.3 0.2 1.6 1 0 0 1 1 1 0 NAD-dependent DNA ligase adenylation domain Osmo_CC PF08946.10 EHT97969.1 - 0.25 11.6 11.1 6.1 7.2 1.9 4.0 3 0 0 3 3 3 0 Osmosensory transporter coiled coil PEP-utilisers_N PF05524.13 EHT97969.1 - 0.37 11.0 2.0 3.8 7.7 0.0 3.4 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal FliD_N PF02465.18 EHT97969.1 - 2.2 9.0 6.0 2.3 8.9 0.1 3.7 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus ScsC_N PF18312.1 EHT97971.1 - 4e-09 36.1 2.0 4e-09 36.1 2.0 1.8 2 0 0 2 2 2 1 Copper resistance protein ScsC N-terminal domain Thioredoxin_4 PF13462.6 EHT97971.1 - 2e-05 24.8 0.4 6.2e-05 23.2 0.1 1.8 1 1 1 2 2 2 1 Thioredoxin DDE_3 PF13358.6 EHT97972.1 - 2.5e-15 56.5 1.0 2.8e-15 56.4 1.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease ParB PF08775.10 EHT97973.1 - 5.9e-35 120.5 0.5 1.1e-34 119.7 0.5 1.4 1 0 0 1 1 1 1 ParB family ParBc PF02195.18 EHT97973.1 - 7.1e-08 32.6 0.0 1.6e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 ParB-like nuclease domain SoPB_HTH PF18090.1 EHT97973.1 - 0.00014 21.9 0.1 0.0004 20.5 0.1 1.8 1 0 0 1 1 1 1 Centromere-binding protein HTH domain Trp_repressor PF01371.19 EHT97973.1 - 0.044 13.9 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Trp repressor protein HTH_54 PF18607.1 EHT97974.1 - 7.3e-39 131.7 0.2 1.3e-38 130.9 0.2 1.4 1 0 0 1 1 1 1 ParA helix turn helix domain AAA_31 PF13614.6 EHT97974.1 - 1.6e-25 90.1 0.0 2.3e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 EHT97974.1 - 1.8e-07 31.2 0.0 2.8e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 EHT97974.1 - 0.001 18.5 1.7 0.078 12.2 0.1 2.5 3 0 0 3 3 3 2 ATPase MipZ Fer4_NifH PF00142.18 EHT97974.1 - 0.0025 17.3 0.0 0.0037 16.7 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 EHT97974.1 - 0.035 13.5 0.3 0.097 12.1 0.3 1.9 1 1 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase VirC1 PF07015.11 EHT97974.1 - 0.039 13.2 0.0 0.29 10.4 0.0 2.2 3 0 0 3 3 3 0 VirC1 protein DNA_pol3_theta PF06440.11 EHT97976.1 - 3e-29 100.5 0.1 3.3e-29 100.3 0.1 1.0 1 0 0 1 1 1 1 DNA polymerase III, theta subunit MdcG PF10620.9 EHT97976.1 - 0.049 13.4 0.1 0.05 13.4 0.1 1.0 1 0 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG Phage_integrase PF00589.22 EHT97978.1 - 5.5e-06 26.3 0.1 6.1e-06 26.1 0.1 1.0 1 0 0 1 1 1 1 Phage integrase family Flagellin_N PF00669.20 EHT97979.1 - 9.9e-20 71.1 6.4 9.9e-20 71.1 6.4 2.1 2 1 0 2 2 2 1 Bacterial flagellin N-terminal helical region FimH_man-bind PF09160.10 EHT97980.1 - 0.055 13.2 0.0 0.063 13.0 0.0 1.0 1 0 0 1 1 1 0 FimH, mannose binding DDE_3 PF13358.6 EHT97981.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHT97981.1 - 7.7e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHT97981.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHT97981.1 - 3.6e-06 26.5 0.3 3.6e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHT97981.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHT97981.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHT97981.1 - 0.087 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHT97981.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 Trans_reg_C PF00486.28 EHT97982.1 - 3.7e-14 52.6 0.0 6.6e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal SLT PF01464.20 EHT97983.1 - 5.3e-19 68.0 0.0 6.8e-19 67.6 0.0 1.1 1 0 0 1 1 1 1 Transglycosylase SLT domain Glucosaminidase PF01832.20 EHT97983.1 - 0.027 14.9 0.0 0.041 14.4 0.0 1.3 1 0 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Lys PF00062.20 EHT97983.1 - 0.055 13.7 0.0 0.077 13.2 0.0 1.3 1 0 0 1 1 1 0 C-type lysozyme/alpha-lactalbumin family Ribonuc_red_lgC PF02867.15 EHT97983.1 - 0.077 11.5 0.1 0.095 11.2 0.1 1.0 1 0 0 1 1 1 0 Ribonucleotide reductase, barrel domain DUF5129 PF17173.4 EHT97984.1 - 0.094 11.8 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5129) CARD_2 PF16739.5 EHT97985.1 - 0.082 12.9 0.5 14 5.7 0.1 2.7 2 1 0 3 3 3 0 Caspase recruitment domain OrgA_MxiK PF09482.10 EHT97986.1 - 9.4e-19 68.0 0.8 1.1e-18 67.7 0.8 1.0 1 0 0 1 1 1 1 Bacterial type III secretion apparatus protein (OrgA_MxiK) YscJ_FliF PF01514.17 EHT97987.1 - 6.5e-19 68.4 1.2 1e-18 67.7 1.2 1.2 1 0 0 1 1 1 1 Secretory protein of YscJ/FliF family VIT1 PF01988.19 EHT97987.1 - 0.63 9.9 2.8 0.99 9.2 0.7 2.0 2 0 0 2 2 2 0 VIT family T3SS_needle_F PF09392.10 EHT97988.1 - 6.6e-06 26.2 0.6 1.2e-05 25.4 0.6 1.4 1 0 0 1 1 1 1 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF T3SS_basalb_I PF17001.5 EHT97988.1 - 0.001 19.6 0.3 0.0011 19.5 0.3 1.2 1 0 0 1 1 1 1 Type III secretion basal body protein I, YscI, HrpB, PscI Med15_fungi PF05397.12 EHT97988.1 - 0.047 14.0 0.1 0.068 13.4 0.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 15 T3SS_needle_F PF09392.10 EHT97989.1 - 1.6e-24 85.9 0.5 1.8e-24 85.7 0.5 1.1 1 0 0 1 1 1 1 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Com_YlbF PF06133.11 EHT97989.1 - 0.017 15.7 0.4 0.024 15.2 0.4 1.2 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA TPR_17 PF13431.6 EHT97989.1 - 0.086 13.3 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat ABC_tran_CTD PF16326.5 EHT97989.1 - 0.11 12.7 0.2 0.15 12.3 0.2 1.3 1 0 0 1 1 1 0 ABC transporter C-terminal domain PrgH PF09480.10 EHT97990.1 - 1.2e-79 268.4 0.1 1.4e-79 268.2 0.1 1.0 1 0 0 1 1 1 1 Type III secretion system protein PrgH-EprH (PrgH) Ank_5 PF13857.6 EHT97990.1 - 0.025 14.9 0.1 0.13 12.6 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) HTH_18 PF12833.7 EHT97991.1 - 3.4e-14 52.9 0.1 6.6e-14 51.9 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 EHT97991.1 - 1.8e-07 31.1 0.6 0.00021 21.3 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Secretin PF00263.21 EHT97992.1 - 1.6e-29 102.7 0.0 2.9e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial type II and III secretion system protein Secretin_N PF03958.17 EHT97992.1 - 8.2e-19 67.8 0.4 6.2e-13 49.0 0.5 2.9 2 1 0 2 2 2 2 Bacterial type II/III secretion system short domain HrpJ PF07201.11 EHT97993.1 - 1.2e-27 97.3 2.0 2.3e-27 96.3 2.0 1.5 1 0 0 1 1 1 1 HrpJ-like domain DNA_ligase_A_N PF04675.14 EHT97993.1 - 0.026 14.9 0.2 0.053 13.9 0.2 1.5 1 0 0 1 1 1 0 DNA ligase N terminus Succ_CoA_lig PF13607.6 EHT97993.1 - 0.03 14.1 0.2 4.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain Glyco_hydro_15 PF00723.21 EHT97993.1 - 0.14 10.9 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 15 FHIPEP PF00771.20 EHT97994.1 - 2.7e-208 693.6 7.9 3.1e-208 693.4 7.9 1.0 1 0 0 1 1 1 1 FHIPEP family OAD_gamma PF04277.13 EHT97994.1 - 0.095 13.3 0.0 0.095 13.3 0.0 3.5 4 0 0 4 4 4 0 Oxaloacetate decarboxylase, gamma chain Invas_SpaK PF03519.14 EHT97995.1 - 6e-19 67.9 0.3 9.2e-19 67.3 0.3 1.4 1 0 0 1 1 1 1 Invasion protein B family ATP-synt_ab PF00006.25 EHT97996.1 - 1.8e-72 243.4 0.0 2.5e-72 243.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain T3SS_ATPase_C PF18269.1 EHT97996.1 - 6.4e-18 64.4 0.7 1.2e-17 63.5 0.7 1.5 1 0 0 1 1 1 1 T3SS EscN ATPase C-terminal domain ATPase_2 PF01637.18 EHT97996.1 - 3e-05 24.1 0.0 6e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea ABC_tran PF00005.27 EHT97996.1 - 0.0055 17.2 0.0 0.011 16.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EHT97996.1 - 0.12 12.7 0.1 0.56 10.6 0.1 2.3 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EHT97996.1 - 0.13 12.7 0.1 0.53 10.7 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EHT97996.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 EHT97996.1 - 0.17 11.9 0.0 0.54 10.3 0.0 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain HrpB7 PF09486.10 EHT97997.1 - 0.00054 20.4 3.4 0.00085 19.7 3.4 1.3 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) APG6_N PF17675.1 EHT97997.1 - 0.0015 19.1 7.1 0.23 12.0 1.2 2.2 2 0 0 2 2 2 2 Apg6 coiled-coil region TMF_DNA_bd PF12329.8 EHT97997.1 - 0.0025 17.8 8.8 0.015 15.2 2.3 2.3 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding FlaC_arch PF05377.11 EHT97997.1 - 0.0027 18.0 5.4 0.37 11.2 1.1 2.4 2 0 0 2 2 2 2 Flagella accessory protein C (FlaC) Spc7 PF08317.11 EHT97997.1 - 0.0062 15.4 7.7 0.095 11.6 2.3 2.0 2 0 0 2 2 2 2 Spc7 kinetochore protein Spc24 PF08286.11 EHT97997.1 - 0.013 15.8 7.9 0.22 11.8 0.9 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 JIP_LZII PF16471.5 EHT97997.1 - 0.018 15.2 4.7 0.43 10.8 0.4 2.4 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II DUF4795 PF16043.5 EHT97997.1 - 0.022 14.4 8.0 0.33 10.5 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) YabA PF06156.13 EHT97997.1 - 0.023 15.3 7.0 0.073 13.7 1.7 2.2 2 0 0 2 2 2 0 Initiation control protein YabA Tropomyosin_1 PF12718.7 EHT97997.1 - 0.025 14.8 5.5 1.2 9.2 0.2 2.2 2 0 0 2 2 2 0 Tropomyosin like DUF4349 PF14257.6 EHT97997.1 - 0.026 14.0 1.3 0.026 14.0 1.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) GCN5L1 PF06320.13 EHT97997.1 - 0.04 14.1 6.9 1.4 9.1 0.6 2.2 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) CENP-F_leu_zip PF10473.9 EHT97997.1 - 0.05 13.6 10.6 0.8 9.7 1.1 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1640 PF07798.11 EHT97997.1 - 0.051 13.6 5.6 0.079 13.0 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Fib_alpha PF08702.10 EHT97997.1 - 0.069 13.3 8.9 1.4 9.1 1.5 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family MscS_porin PF12795.7 EHT97997.1 - 0.072 12.6 16.6 0.12 11.9 16.6 1.3 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain FPP PF05911.11 EHT97997.1 - 0.079 11.1 7.2 0.09 11.0 7.2 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DivIC PF04977.15 EHT97997.1 - 0.092 12.5 10.3 0.97 9.2 1.2 2.4 2 0 0 2 2 2 0 Septum formation initiator GrpE PF01025.19 EHT97997.1 - 0.099 12.3 7.1 1.1 8.9 2.0 2.1 2 0 0 2 2 2 0 GrpE Vac_Fusion PF02346.16 EHT97997.1 - 0.1 12.3 1.9 0.21 11.2 0.3 2.2 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 DUF1664 PF07889.12 EHT97997.1 - 0.12 12.4 4.8 4.5 7.3 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Tho2 PF11262.8 EHT97997.1 - 0.13 11.4 5.3 0.16 11.1 5.3 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Prominin PF05478.11 EHT97997.1 - 0.14 10.1 4.9 0.16 9.9 4.9 1.0 1 0 0 1 1 1 0 Prominin SPAM PF02090.15 EHT97997.1 - 0.15 11.9 14.1 0.6 9.9 14.0 1.8 1 1 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein Phage_int_SAM_6 PF18644.1 EHT97997.1 - 0.34 10.9 6.2 0.81 9.7 0.4 2.2 1 1 1 2 2 2 0 Phage integrase SAM-like domain DUF4140 PF13600.6 EHT97997.1 - 0.39 11.2 3.6 13 6.3 0.3 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) E2F_CC-MB PF16421.5 EHT97997.1 - 0.47 10.9 7.0 0.81 10.1 2.2 2.2 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain PI_PP_I PF18363.1 EHT97997.1 - 0.6 10.3 5.8 3.9 7.7 0.8 2.1 2 0 0 2 2 2 0 Phosphoinositide phosphatase insertion domain Exonuc_VII_L PF02601.15 EHT97997.1 - 0.67 9.5 11.4 5 6.6 11.5 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit KxDL PF10241.9 EHT97997.1 - 0.93 9.8 12.7 0.079 13.2 2.0 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein FapA PF03961.13 EHT97997.1 - 0.97 8.0 7.4 1.2 7.7 7.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Ax_dynein_light PF10211.9 EHT97997.1 - 1.1 9.2 11.9 0.16 11.9 3.4 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain BORCS7 PF16088.5 EHT97997.1 - 1.4 9.2 7.5 1 9.6 1.4 2.2 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 7 PI3K_P85_iSH2 PF16454.5 EHT97997.1 - 1.6 8.3 16.7 10 5.7 16.7 1.9 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF724 PF05266.14 EHT97997.1 - 1.6 8.5 10.9 3.9 7.3 2.5 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF724) Prefoldin PF02996.17 EHT97997.1 - 2 8.3 11.5 5.3 7.0 2.0 2.3 2 0 0 2 2 2 0 Prefoldin subunit DegQ PF08181.11 EHT97997.1 - 2.2 8.5 7.7 0.73 10.0 0.2 3.0 3 1 0 3 3 3 0 DegQ (SacQ) family DUF4407 PF14362.6 EHT97997.1 - 3.8 6.8 8.0 35 3.6 8.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) SlyX PF04102.12 EHT97997.1 - 5 7.8 12.8 6.8 7.4 3.3 2.3 2 0 0 2 2 2 0 SlyX Prefoldin_2 PF01920.20 EHT97997.1 - 5.9 6.9 18.6 0.51 10.3 3.2 2.9 2 1 1 3 3 3 0 Prefoldin subunit SPAN PF02510.14 EHT97998.1 - 0.001 18.3 0.6 0.0012 18.1 0.6 1.3 1 0 0 1 1 1 1 Surface presentation of antigens protein FliMN_C PF01052.20 EHT97999.1 - 1.6e-17 63.3 0.0 2e-10 40.5 0.0 2.2 2 0 0 2 2 2 2 Type III flagellar switch regulator (C-ring) FliN C-term FliP PF00813.20 EHT98000.1 - 2.8e-61 206.8 8.6 3.3e-61 206.5 8.6 1.0 1 0 0 1 1 1 1 FliP family Bac_export_3 PF01313.19 EHT98001.1 - 1.2e-19 69.9 8.6 1.4e-19 69.8 8.6 1.1 1 0 0 1 1 1 1 Bacterial export proteins, family 3 SLATT_5 PF18160.1 EHT98001.1 - 0.069 12.5 0.8 0.077 12.3 0.8 1.0 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF2613 PF11021.8 EHT98001.1 - 0.087 13.0 0.5 0.15 12.2 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) Glucos_trans_II PF14264.6 EHT98001.1 - 0.18 11.1 6.9 0.19 11.0 6.9 1.0 1 0 0 1 1 1 0 Glucosyl transferase GtrII Bac_export_1 PF01311.20 EHT98002.1 - 1.3e-40 139.4 23.3 1.5e-40 139.2 23.3 1.0 1 0 0 1 1 1 1 Bacterial export proteins, family 1 Bac_export_2 PF01312.19 EHT98003.1 - 5.3e-88 295.4 4.3 5.9e-88 295.2 4.3 1.0 1 0 0 1 1 1 1 FlhB HrpN YscU SpaS Family UPF0182 PF03699.13 EHT98003.1 - 2.4 6.2 5.3 3.3 5.7 5.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) TPR_3 PF07720.12 EHT98004.1 - 4.1e-18 65.0 14.4 4.7e-09 36.1 3.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EHT98004.1 - 1.7e-06 27.7 8.7 0.02 15.0 1.5 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EHT98004.1 - 3.7e-05 23.9 4.8 0.0089 16.3 1.6 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EHT98004.1 - 0.0017 18.9 4.7 0.0027 18.3 2.1 2.3 2 1 0 2 2 2 1 Tetratricopeptide repeat PknG_TPR PF16918.5 EHT98004.1 - 0.036 12.8 0.0 0.052 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat TPR_1 PF00515.28 EHT98004.1 - 0.036 13.9 11.6 0.052 13.4 1.9 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EHT98004.1 - 0.039 14.6 11.0 0.18 12.5 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 EHT98004.1 - 0.043 14.0 0.8 0.073 13.2 0.8 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EHT98004.1 - 0.072 13.3 10.2 0.13 12.5 4.9 2.8 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EHT98004.1 - 1.1 9.2 3.9 22 5.1 0.2 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EHT98004.1 - 2.1 8.7 7.1 0.26 11.6 1.4 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat SseC PF04888.12 EHT98005.1 - 6e-47 160.8 61.9 6e-47 160.8 61.9 3.2 2 1 0 2 2 2 1 Secretion system effector C (SseC) like family T3SSipB PF16535.5 EHT98005.1 - 1.1e-09 39.0 21.5 1.1e-09 39.0 21.5 5.4 3 2 2 5 5 5 1 Type III cell invasion protein SipB DUF2207 PF09972.9 EHT98005.1 - 0.08 11.7 3.1 0.065 12.0 1.0 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Goodbye PF17109.5 EHT98005.1 - 0.094 13.2 0.3 0.094 13.2 0.3 4.5 4 1 2 6 6 6 0 fungal STAND N-terminal Goodbye domain DUF4897 PF16238.5 EHT98005.1 - 4 7.3 7.2 1 9.1 1.5 2.8 2 2 1 3 3 3 0 Domain of unknown function (DUF4897) YCII PF03795.14 EHT98006.1 - 0.017 15.5 1.4 8.4 6.9 0.2 2.9 2 1 0 2 2 2 0 YCII-related domain Organ_specific PF10950.8 EHT98006.1 - 4.8 7.9 7.4 0.69 10.6 0.7 2.8 3 1 0 3 3 3 0 Organ specific protein T3SS_TC PF06511.11 EHT98007.1 - 5.9e-25 88.4 15.1 2.4e-13 50.2 0.7 2.3 2 0 0 2 2 2 2 Type III secretion systems tip complex components YABBY PF04690.13 EHT98007.1 - 0.27 11.8 2.0 0.51 10.9 0.4 2.0 1 1 1 2 2 2 0 YABBY protein Kinase-PPPase PF03618.14 EHT98007.1 - 0.35 10.6 5.7 0.48 10.2 4.1 1.9 2 0 0 2 2 2 0 Kinase/pyrophosphorylase Fez1 PF06818.15 EHT98007.1 - 1.4 9.3 6.1 4.7 7.6 5.9 2.0 1 1 0 1 1 1 0 Fez1 Translin PF01997.16 EHT98007.1 - 1.6 8.7 5.8 1.8 8.5 1.5 2.3 1 1 1 2 2 2 0 Translin family Carbpep_Y_N PF05388.11 EHT98007.1 - 3.6 8.2 7.9 20 5.7 0.1 3.5 2 1 1 4 4 4 0 Carboxypeptidase Y pro-peptide PP-binding PF00550.25 EHT98010.1 - 2.3e-05 24.7 0.3 2.6e-05 24.5 0.3 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site GHL10 PF02638.15 EHT98012.1 - 2.8e-07 29.9 0.0 3.2e-07 29.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 DUF1460 PF07313.12 EHT98013.1 - 5.1e-75 251.5 0.0 6.6e-75 251.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1460) HTH_28 PF13518.6 EHT98014.1 - 4.7e-12 45.8 1.7 1.2e-11 44.6 1.7 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.6 EHT98014.1 - 3.9e-10 40.2 1.4 3.9e-10 40.2 1.4 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 EHT98014.1 - 1.7e-09 37.2 0.6 4.4e-09 35.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 EHT98014.1 - 2.8e-09 36.9 2.6 2.8e-09 36.9 2.6 1.8 2 0 0 2 2 2 1 Winged helix-turn helix rve PF00665.26 EHT98014.1 - 4.7e-06 26.8 0.1 1.3e-05 25.3 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 EHT98014.1 - 0.00079 19.1 0.6 0.0016 18.2 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain LZ_Tnp_IS481 PF13011.6 EHT98014.1 - 0.0015 19.0 1.2 0.0053 17.3 0.5 2.2 2 0 0 2 2 2 1 leucine-zipper of insertion element IS481 WVELL PF14043.6 EHT98014.1 - 0.041 13.7 0.0 0.42 10.5 0.0 2.5 2 0 0 2 2 2 0 WVELL protein efThoc1 PF11957.8 EHT98014.1 - 0.053 12.2 0.0 0.077 11.7 0.0 1.2 1 0 0 1 1 1 0 THO complex subunit 1 transcription elongation factor N36 PF11438.8 EHT98014.1 - 0.068 13.0 0.5 0.24 11.2 0.5 2.0 1 0 0 1 1 1 0 36-mer N-terminal peptide of the N protein (N36) TetR_C_28 PF17937.1 EHT98014.1 - 1.2 9.6 4.8 2.7 8.5 0.1 3.0 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Shigella_OspC PF06128.11 EHT98016.1 - 4e-108 361.6 7.4 4e-108 361.6 7.4 2.1 2 1 0 2 2 2 1 Shigella flexneri OspC protein Ank_2 PF12796.7 EHT98016.1 - 0.054 14.1 0.2 0.68 10.6 0.1 2.4 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EHT98016.1 - 0.13 12.9 0.0 2.2 9.1 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat DDE_3 PF13358.6 EHT98017.1 - 6.4e-11 42.2 0.0 1.2e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 EHT98017.1 - 8.6e-11 41.3 0.7 3e-09 36.4 0.1 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 EHT98017.1 - 3e-09 37.4 1.1 2.3e-08 34.5 0.3 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 EHT98017.1 - 1.8e-07 31.1 0.7 9e-07 28.8 0.3 2.2 2 0 0 2 2 2 1 Winged helix-turn helix HTH_33 PF13592.6 EHT98017.1 - 1.9e-06 27.4 4.2 3.7e-06 26.5 0.3 2.6 3 0 0 3 3 3 1 Winged helix-turn helix HTH_28 PF13518.6 EHT98017.1 - 9.5e-06 25.6 0.3 0.00017 21.6 0.2 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHT98017.1 - 0.025 15.1 0.2 0.051 14.1 0.2 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 HTH_38 PF13936.6 EHT98017.1 - 0.036 13.8 0.6 0.13 12.0 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain DDE_Tnp_IS66 PF03050.14 EHT98018.1 - 1.2e-85 287.4 4.9 2.9e-85 286.2 0.1 2.1 2 0 0 2 2 2 1 Transposase IS66 family zf-IS66 PF13005.7 EHT98018.1 - 1.2e-14 54.4 1.5 2.9e-14 53.2 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT98018.1 - 9.5e-12 45.5 9.0 2.1e-11 44.4 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHT98018.1 - 0.013 15.3 6.4 0.022 14.6 6.4 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Csm1_N PF18504.1 EHT98018.1 - 0.016 15.5 4.4 0.072 13.4 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Phage_HK97_TLTM PF06120.11 EHT98018.1 - 0.017 14.3 1.7 0.035 13.3 1.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein FUSC PF04632.12 EHT98018.1 - 0.03 12.9 6.8 0.048 12.2 6.8 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 EHT98018.1 - 0.031 13.9 2.4 0.037 13.6 0.8 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit Tho2 PF11262.8 EHT98018.1 - 0.043 13.0 0.4 0.071 12.3 0.4 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Troponin PF00992.20 EHT98018.1 - 0.049 13.9 3.1 0.088 13.1 3.1 1.4 1 0 0 1 1 1 0 Troponin LXG PF04740.12 EHT98018.1 - 0.082 12.6 2.7 0.28 10.9 0.4 2.2 1 1 1 2 2 2 0 LXG domain of WXG superfamily UME PF08064.13 EHT98018.1 - 0.11 12.5 0.7 18 5.3 0.0 3.1 2 1 1 3 3 3 0 UME (NUC010) domain ERM PF00769.19 EHT98018.1 - 0.12 12.1 10.8 0.21 11.4 10.8 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Zn-ribbon_8 PF09723.10 EHT98018.1 - 0.27 11.4 1.7 0.86 9.8 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain DHR10 PF18595.1 EHT98018.1 - 0.3 11.2 10.9 0.54 10.3 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF1192 PF06698.11 EHT98018.1 - 0.36 10.9 5.3 2.9 8.0 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHT98018.1 - 0.9 8.7 3.1 1.4 8.1 3.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHT98018.1 - 2.1 7.9 7.8 4.9 6.7 7.8 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 HalX PF08663.10 EHT98018.1 - 2.6 8.4 6.9 0.49 10.8 3.1 1.8 2 0 0 2 2 1 0 HalX domain OmpH PF03938.14 EHT98018.1 - 2.8 8.3 8.0 5.7 7.3 8.0 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 EHT98018.1 - 5.4 7.7 8.8 10 6.8 1.8 3.1 1 1 1 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHT98019.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHT98020.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT98020.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT98020.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT98020.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix HTH_28 PF13518.6 EHT98021.1 - 4.7e-12 45.8 1.7 1.2e-11 44.6 1.7 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.6 EHT98021.1 - 3.9e-10 40.2 1.4 3.9e-10 40.2 1.4 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 EHT98021.1 - 1.7e-09 37.2 0.6 4.4e-09 35.9 0.6 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 EHT98021.1 - 2.8e-09 36.9 2.6 2.8e-09 36.9 2.6 1.8 2 0 0 2 2 2 1 Winged helix-turn helix rve PF00665.26 EHT98021.1 - 4.7e-06 26.8 0.1 1.3e-05 25.3 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 EHT98021.1 - 0.00079 19.1 0.6 0.0016 18.2 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain LZ_Tnp_IS481 PF13011.6 EHT98021.1 - 0.0015 19.0 1.2 0.0053 17.3 0.5 2.2 2 0 0 2 2 2 1 leucine-zipper of insertion element IS481 WVELL PF14043.6 EHT98021.1 - 0.041 13.7 0.0 0.42 10.5 0.0 2.5 2 0 0 2 2 2 0 WVELL protein efThoc1 PF11957.8 EHT98021.1 - 0.053 12.2 0.0 0.077 11.7 0.0 1.2 1 0 0 1 1 1 0 THO complex subunit 1 transcription elongation factor N36 PF11438.8 EHT98021.1 - 0.068 13.0 0.5 0.24 11.2 0.5 2.0 1 0 0 1 1 1 0 36-mer N-terminal peptide of the N protein (N36) TetR_C_28 PF17937.1 EHT98021.1 - 1.2 9.6 4.8 2.7 8.5 0.1 3.0 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain HTH_3 PF01381.22 EHT98022.1 - 1.8e-08 34.3 0.0 2.4e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EHT98022.1 - 0.00055 20.2 0.0 0.00076 19.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 EHT98022.1 - 0.00082 19.2 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_19 PF12844.7 EHT98022.1 - 0.0016 18.4 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_50 PF18024.1 EHT98022.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_10 PF04967.12 EHT98022.1 - 0.045 13.5 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain HTH_26 PF13443.6 EHT98022.1 - 0.067 13.6 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain E3_binding PF02817.17 EHT98022.1 - 0.077 13.4 0.1 0.2 12.0 0.1 1.7 1 0 0 1 1 1 0 e3 binding domain CENP-B_N PF04218.13 EHT98022.1 - 0.088 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Cro PF09048.10 EHT98022.1 - 0.099 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Cro HTH_38 PF13936.6 EHT98022.1 - 0.21 11.4 0.0 0.44 10.3 0.0 1.5 2 0 0 2 2 2 0 Helix-turn-helix domain HigB-like_toxin PF05015.13 EHT98023.1 - 7.8e-19 67.9 0.0 8.6e-19 67.8 0.0 1.0 1 0 0 1 1 1 1 RelE-like toxin of type II toxin-antitoxin system HigB DUF1380 PF07128.12 EHT98024.1 - 1.7e-08 34.7 0.1 3.4e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1380) Methyltransf_25 PF13649.6 EHT98024.1 - 0.019 15.7 0.1 0.074 13.8 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain Rhomboid PF01694.22 EHT98024.1 - 0.036 14.1 0.3 0.099 12.6 0.2 1.6 1 1 1 2 2 2 0 Rhomboid family N6_Mtase PF02384.16 EHT98024.1 - 0.12 11.6 0.0 0.24 10.6 0.0 1.5 2 0 0 2 2 2 0 N-6 DNA Methylase DUF1380 PF07128.12 EHT98025.1 - 2.4e-07 31.0 1.6 2.8e-07 30.8 1.5 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1380) DUF1053 PF06327.14 EHT98025.1 - 0.15 12.7 0.3 0.2 12.2 0.3 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) EXS PF03124.14 EHT98025.1 - 0.19 11.0 0.1 0.22 10.8 0.1 1.1 1 0 0 1 1 1 0 EXS family HTH_Tnp_1 PF01527.20 EHT98026.1 - 8e-09 35.7 0.0 1.6e-08 34.7 0.0 1.5 2 0 0 2 2 2 1 Transposase TMEM51 PF15345.6 EHT98026.1 - 0.18 11.6 0.0 0.22 11.4 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 DDE_Tnp_1_5 PF13737.6 EHT98028.1 - 1e-25 90.2 0.1 2.3e-25 89.1 0.0 1.5 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 EHT98028.1 - 2.2e-08 34.0 0.0 2.6e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain MFS_1 PF07690.16 EHT98029.1 - 1.1e-08 34.4 18.9 1.1e-08 34.4 18.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF805 PF05656.14 EHT98029.1 - 0.046 14.1 3.2 0.045 14.2 1.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF805) DUF2304 PF10066.9 EHT98029.1 - 0.23 11.7 7.7 0.039 14.2 1.8 2.6 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2304) Gram_pos_anchor PF00746.21 EHT98029.1 - 4.2 7.4 0.0 4.2 7.4 0.0 4.9 7 0 0 7 7 7 0 LPXTG cell wall anchor motif Mtd_N PF18454.1 EHT98030.1 - 0.22 11.6 0.0 0.36 10.9 0.0 1.3 1 0 0 1 1 1 0 Major tropism determinant N-terminal domain IncFII_repA PF02387.15 EHT98031.1 - 0.01 15.1 0.0 0.01 15.1 0.0 1.0 1 0 0 1 1 1 0 IncFII RepA protein family N36 PF11438.8 EHT98032.1 - 0.074 12.9 1.9 0.12 12.2 1.4 1.7 1 1 0 1 1 1 0 36-mer N-terminal peptide of the N protein (N36) HTH_Tnp_1 PF01527.20 EHT98033.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT98033.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT98033.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT98033.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHT98034.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHT98035.1 - 2.2e-98 329.2 3.2 1.6e-97 326.4 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT98035.1 - 3.2e-16 59.3 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT98035.1 - 8e-15 55.0 1.3 1.9e-14 53.8 1.3 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT98035.1 - 1.7e-11 44.7 9.6 3.5e-11 43.7 9.6 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHT98035.1 - 0.017 14.9 6.4 0.027 14.3 6.4 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Phage_HK97_TLTM PF06120.11 EHT98035.1 - 0.022 14.0 1.7 0.042 13.0 1.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHT98035.1 - 0.022 15.1 4.3 0.091 13.1 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Exonuc_VII_L PF02601.15 EHT98035.1 - 0.029 14.0 1.8 0.039 13.5 0.6 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit FUSC PF04632.12 EHT98035.1 - 0.036 12.6 6.9 0.056 12.0 6.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tho2 PF11262.8 EHT98035.1 - 0.057 12.6 0.5 0.094 11.9 0.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Troponin PF00992.20 EHT98035.1 - 0.062 13.6 3.0 0.11 12.8 3.0 1.3 1 0 0 1 1 1 0 Troponin LXG PF04740.12 EHT98035.1 - 0.11 12.2 2.6 0.33 10.6 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHT98035.1 - 0.16 11.8 10.8 0.26 11.1 10.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family UME PF08064.13 EHT98035.1 - 0.16 11.9 0.5 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain HalX PF08663.10 EHT98035.1 - 0.23 11.8 3.1 0.59 10.5 3.1 1.7 1 0 0 1 1 1 0 HalX domain DHR10 PF18595.1 EHT98035.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF1192 PF06698.11 EHT98035.1 - 0.48 10.5 5.3 3.4 7.8 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHT98035.1 - 1.1 8.4 3.1 1.7 7.8 3.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHT98035.1 - 2.8 7.4 7.9 6.1 6.3 7.9 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHT98035.1 - 3.3 8.1 7.9 6.7 7.0 7.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 EHT98035.1 - 7.2 7.3 8.7 7.7 7.2 1.0 3.0 1 1 1 2 2 2 0 SlyX MCPsignal PF00015.21 EHT98037.1 - 1.7e-40 138.6 15.2 3.7e-40 137.6 15.2 1.6 1 1 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3130 PF11328.8 EHT98037.1 - 0.015 15.5 1.0 0.022 15.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3130 BLOC1_2 PF10046.9 EHT98037.1 - 0.019 15.2 0.6 0.37 11.1 0.1 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF5033 PF16436.5 EHT98037.1 - 0.15 12.0 0.1 0.29 11.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5033) CesT PF05932.13 EHT98038.1 - 1.6e-13 50.8 0.4 1.9e-13 50.5 0.4 1.1 1 0 0 1 1 1 1 Tir chaperone protein (CesT) family AvrE_T3Es PF11725.8 EHT98039.1 - 3.2e-279 929.8 15.4 4.2e-279 929.4 15.4 1.0 1 0 0 1 1 1 1 AvrE-family Type-III effector proteins (T3Es) Tachylectin PF14517.6 EHT98039.1 - 0.00088 18.9 0.1 0.65 9.5 0.0 3.4 3 0 0 3 3 3 2 Tachylectin Hairpins PF04877.12 EHT98040.1 - 9.1e-72 242.3 20.7 4.6e-66 223.6 13.8 2.0 1 1 1 2 2 2 2 HrpZ Secretin PF00263.21 EHT98043.1 - 7.3e-35 120.1 0.1 1.3e-34 119.2 0.1 1.5 1 0 0 1 1 1 1 Bacterial type II and III secretion system protein Secretin_N PF03958.17 EHT98043.1 - 9.3e-24 83.6 1.2 8.6e-19 67.7 0.6 3.3 3 0 0 3 3 3 2 Bacterial type II/III secretion system short domain TraK PF06586.11 EHT98043.1 - 9.9e-06 25.4 0.7 2e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 TraK protein Mu-like_Pro PF10123.9 EHT98043.1 - 0.1 12.1 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Mu-like prophage I protein HrpF PF06266.12 EHT98044.1 - 1.5e-32 111.7 0.8 1.6e-32 111.6 0.8 1.0 1 0 0 1 1 1 1 HrpF protein Dmd PF17587.2 EHT98044.1 - 0.078 13.3 0.0 0.089 13.1 0.0 1.2 1 0 0 1 1 1 0 Discriminator of mRNA degradation HrpE PF06188.12 EHT98045.1 - 3.1e-42 144.6 15.6 3.5e-42 144.5 15.6 1.0 1 0 0 1 1 1 1 HrpE/YscL/FliH and V-type ATPase subunit E vATP-synt_E PF01991.18 EHT98045.1 - 0.0016 17.9 5.8 0.0025 17.2 5.8 1.4 1 1 0 1 1 1 1 ATP synthase (E/31 kDa) subunit TPR_19 PF14559.6 EHT98045.1 - 0.0057 17.1 2.2 0.069 13.7 0.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat HCV_NS2 PF01538.18 EHT98045.1 - 0.09 12.4 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS2 V-ATPase_G PF03179.15 EHT98045.1 - 0.11 13.0 4.7 0.19 12.3 4.7 1.3 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Cdh1_DBD_1 PF18196.1 EHT98045.1 - 0.18 12.1 2.7 0.21 11.9 2.2 1.4 1 1 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 DivIVA PF05103.13 EHT98045.1 - 4 7.5 10.4 0.61 10.2 5.7 1.9 1 1 0 1 1 1 0 DivIVA protein YscJ_FliF PF01514.17 EHT98047.1 - 1.8e-17 63.6 0.0 2.5e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Secretory protein of YscJ/FliF family T3SS_basalb_I PF17001.5 EHT98048.1 - 1.9e-17 63.6 2.3 2e-17 63.5 2.3 1.0 1 0 0 1 1 1 1 Type III secretion basal body protein I, YscI, HrpB, PscI MT0933_antitox PF14013.6 EHT98048.1 - 0.042 14.2 0.3 0.062 13.6 0.3 1.3 1 0 0 1 1 1 0 MT0933-like antitoxin protein Sigma54_activat PF00158.26 EHT98050.1 - 1.3e-57 194.2 0.0 2.4e-57 193.3 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EHT98050.1 - 1.8e-14 54.1 0.0 5e-14 52.6 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 EHT98050.1 - 6.4e-09 35.9 0.0 1.1e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) HTH_8 PF02954.19 EHT98050.1 - 2.8e-08 33.4 0.0 8.1e-08 31.9 0.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family AAA PF00004.29 EHT98050.1 - 3.8e-06 27.3 0.0 6.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EHT98050.1 - 1e-05 25.0 0.0 0.0035 16.7 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EHT98050.1 - 4.2e-05 23.4 0.0 6.9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 EHT98050.1 - 0.00015 22.0 0.0 0.00037 20.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) MCM PF00493.23 EHT98050.1 - 0.00084 18.5 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain HTH_1 PF00126.27 EHT98050.1 - 0.0033 17.4 0.0 0.067 13.1 0.0 2.7 3 0 0 3 3 3 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_23 PF13384.6 EHT98050.1 - 0.027 14.3 0.0 0.063 13.1 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT98050.1 - 0.053 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_30 PF13556.6 EHT98050.1 - 0.054 13.3 0.1 0.19 11.6 0.1 1.9 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_50 PF18024.1 EHT98050.1 - 0.086 12.5 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain TsaE PF02367.17 EHT98050.1 - 0.092 12.8 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 EHT98050.1 - 0.29 11.4 1.2 4.9 7.4 0.3 2.9 2 2 0 2 2 2 0 AAA domain Response_reg PF00072.24 EHT98051.1 - 1.6e-28 99.1 0.1 3.6e-28 98.0 0.0 1.6 2 0 0 2 2 2 1 Response regulator receiver domain GerE PF00196.19 EHT98051.1 - 4.8e-16 58.0 2.5 5.9e-16 57.8 1.5 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family Sigma70_r4 PF04545.16 EHT98051.1 - 0.0032 16.9 0.1 0.0077 15.7 0.1 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_29 PF13551.6 EHT98051.1 - 0.0036 17.3 0.1 0.007 16.4 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 EHT98051.1 - 0.0055 16.8 0.1 0.021 14.9 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_5 PF01022.20 EHT98051.1 - 0.016 15.1 0.7 0.13 12.2 0.1 2.3 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family PAS_4 PF08448.10 EHT98052.1 - 6.4e-23 81.1 0.0 2.7e-12 46.9 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 EHT98052.1 - 2.6e-19 69.3 2.2 1.5e-10 41.0 0.0 3.5 4 1 0 4 4 4 2 PAS fold PAS_9 PF13426.7 EHT98052.1 - 6.6e-19 68.1 0.7 5.4e-09 36.2 0.0 3.0 3 1 0 3 3 3 2 PAS domain HisKA_3 PF07730.13 EHT98052.1 - 2.3e-15 56.9 1.2 2.3e-15 56.9 1.2 2.1 2 0 0 2 2 2 1 Histidine kinase PAS_8 PF13188.7 EHT98052.1 - 6.4e-14 51.6 0.8 3.5e-06 26.9 0.0 2.5 2 0 0 2 2 2 2 PAS domain HATPase_c PF02518.26 EHT98052.1 - 2.5e-07 31.2 0.6 1.9e-06 28.3 0.3 2.5 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 EHT98052.1 - 1.3e-05 25.4 0.1 0.00013 22.1 0.0 2.6 2 1 0 2 2 2 1 PAS fold HATPase_c_2 PF13581.6 EHT98052.1 - 0.00016 21.6 0.4 0.00054 19.9 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain MEKHLA PF08670.11 EHT98052.1 - 0.0067 16.3 0.0 2.3 8.1 0.0 2.4 2 0 0 2 2 2 2 MEKHLA domain Sigma70_r4_2 PF08281.12 EHT98053.1 - 7e-12 44.8 0.1 1.1e-11 44.2 0.1 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EHT98053.1 - 4.3e-08 32.6 0.1 6.9e-08 31.9 0.1 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 EHT98053.1 - 7.8e-06 25.6 0.2 1.2e-05 25.0 0.2 1.3 1 0 0 1 1 1 1 Sigma-70 region 2 DUF2089 PF09862.9 EHT98053.1 - 0.00014 21.9 0.0 0.00018 21.5 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2089) HTH_30 PF13556.6 EHT98053.1 - 0.00036 20.3 0.0 0.00061 19.5 0.0 1.4 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_24 PF13412.6 EHT98053.1 - 0.014 14.9 0.1 0.032 13.8 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding ING PF12998.7 EHT98053.1 - 0.018 15.6 0.0 0.033 14.8 0.0 1.5 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding HTH_23 PF13384.6 EHT98053.1 - 0.11 12.4 0.0 0.38 10.6 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain Clp_N PF02861.20 EHT98053.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Clp amino terminal domain, pathogenicity island component HrpJ PF07201.11 EHT98054.1 - 1.3e-48 165.4 5.7 2.7e-48 164.4 5.7 1.4 1 0 0 1 1 1 1 HrpJ-like domain TyeA PF09059.10 EHT98054.1 - 0.00028 20.9 0.0 0.0027 17.8 0.0 2.4 2 0 0 2 2 2 1 TyeA FHIPEP PF00771.20 EHT98055.1 - 3.7e-207 689.9 1.2 4.2e-207 689.7 1.2 1.0 1 0 0 1 1 1 1 FHIPEP family DUF454 PF04304.13 EHT98055.1 - 0.12 12.4 0.1 0.12 12.4 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF454) DUF4131 PF13567.6 EHT98055.1 - 8.6 6.0 9.3 0.21 11.2 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Yop-YscD_cpl PF16697.5 EHT98056.1 - 7.9e-18 64.6 0.0 9.5e-17 61.1 0.0 2.3 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FHA PF00498.26 EHT98056.1 - 0.0021 18.4 0.0 0.031 14.6 0.0 2.4 2 0 0 2 2 2 1 FHA domain Yop-YscD_ppl PF16693.5 EHT98056.1 - 0.0055 16.2 0.1 0.0081 15.6 0.1 1.1 1 0 0 1 1 1 1 Inner membrane component of T3SS, periplasmic domain ATP-synt_ab PF00006.25 EHT98057.1 - 2.5e-71 239.7 0.0 3.2e-71 239.4 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain T3SS_ATPase_C PF18269.1 EHT98057.1 - 9.1e-21 73.5 0.0 1.7e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 T3SS EscN ATPase C-terminal domain ATP-synt_ab_N PF02874.23 EHT98057.1 - 0.0012 19.4 0.1 0.0038 17.7 0.0 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain ATPase_2 PF01637.18 EHT98057.1 - 0.0077 16.2 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 EHT98057.1 - 0.017 15.6 0.0 0.056 14.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EHT98057.1 - 0.018 15.4 2.7 0.051 14.0 1.6 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 EHT98057.1 - 0.018 15.3 0.0 0.035 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EHT98057.1 - 0.022 15.3 0.0 0.046 14.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 EHT98057.1 - 0.026 14.8 0.0 0.056 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EHT98057.1 - 0.035 14.0 0.6 0.84 9.5 0.2 3.0 2 1 0 2 2 2 0 NACHT domain Viral_helicase1 PF01443.18 EHT98057.1 - 0.036 13.8 0.0 0.076 12.7 0.0 1.5 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 EHT98057.1 - 0.041 13.5 1.9 1.7 8.2 1.9 2.5 1 1 0 1 1 1 0 AAA domain Neur_chan_memb PF02932.16 EHT98058.1 - 1.8 8.5 10.5 2.1 8.3 10.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region LsmAD PF06741.13 EHT98058.1 - 6 7.5 8.4 4.8 7.8 1.9 2.5 2 1 0 2 2 2 0 LsmAD domain ALMT PF11744.8 EHT98058.1 - 6.6 5.4 9.2 7.3 5.3 9.2 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter TssC PF17541.2 EHT98058.1 - 7.7 5.2 7.1 21 3.8 7.0 1.7 1 1 1 2 2 2 0 Type VI secretion system, TssC, VipB FliMN_C PF01052.20 EHT98060.1 - 1.2e-19 70.0 0.3 6.7e-16 58.1 0.1 2.4 2 0 0 2 2 2 2 Type III flagellar switch regulator (C-ring) FliN C-term FliP PF00813.20 EHT98061.1 - 1.7e-60 204.2 12.3 2e-60 204.0 12.3 1.0 1 0 0 1 1 1 1 FliP family Bac_export_3 PF01313.19 EHT98062.1 - 1.5e-23 82.5 11.7 1.8e-23 82.2 11.7 1.2 1 0 0 1 1 1 1 Bacterial export proteins, family 3 PTPS_related PF10131.9 EHT98062.1 - 0.0045 15.4 2.1 0.0053 15.2 2.1 1.0 1 0 0 1 1 1 1 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein Syndecan PF01034.20 EHT98062.1 - 0.14 12.1 2.7 0.27 11.2 2.7 1.6 1 0 0 1 1 1 0 Syndecan domain Bac_export_2 PF01312.19 EHT98062.1 - 2.7 7.1 7.3 2.1 7.5 4.6 1.7 1 1 1 2 2 2 0 FlhB HrpN YscU SpaS Family Bac_export_1 PF01311.20 EHT98063.1 - 2e-43 148.6 21.6 2.4e-43 148.4 21.6 1.0 1 0 0 1 1 1 1 Bacterial export proteins, family 1 Bac_export_2 PF01312.19 EHT98064.1 - 1.1e-92 310.8 0.6 1.2e-92 310.6 0.6 1.0 1 0 0 1 1 1 1 FlhB HrpN YscU SpaS Family DUF3721 PF12518.8 EHT98065.1 - 0.0031 17.3 0.6 0.0071 16.2 0.6 1.6 1 0 0 1 1 1 1 Protein of unknown function Acetyltransf_1 PF00583.25 EHT98065.1 - 0.0056 16.9 0.1 0.0079 16.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family VirK PF06903.12 EHT98066.1 - 1.3e-21 76.5 0.0 1.5e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 VirK protein Virulence_fact PF13769.6 EHT98067.1 - 0.061 13.6 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 Virulence factor Sarcoglycan_1 PF04790.13 EHT98067.1 - 0.066 12.6 0.0 0.085 12.2 0.0 1.2 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein ATP-grasp_4 PF13535.6 EHT98068.1 - 0.0006 19.4 0.0 0.0056 16.3 0.0 2.4 2 1 0 2 2 2 1 ATP-grasp domain ATP-grasp_4 PF13535.6 EHT98069.1 - 6.6e-08 32.3 0.0 1.7e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EHT98069.1 - 0.0021 17.6 0.0 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 EHT98069.1 - 0.016 14.7 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.11 EHT98069.1 - 0.13 11.8 0.0 0.36 10.4 0.0 1.7 1 0 0 1 1 1 0 RimK-like ATP-grasp domain TTL PF03133.15 EHT98069.1 - 0.16 11.1 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Tubulin-tyrosine ligase family Amidinotransf PF02274.17 EHT98070.1 - 1e-05 24.8 0.0 0.89 8.6 0.2 3.8 3 1 0 3 3 3 3 Amidinotransferase Glucodextran_N PF09137.11 EHT98071.1 - 1.5e-55 188.6 0.0 1.7e-55 188.4 0.0 1.0 1 0 0 1 1 1 1 Glucodextranase, domain N Glucodextran_N PF09137.11 EHT98072.1 - 6.8e-26 91.4 2.6 8.7e-26 91.0 2.6 1.1 1 0 0 1 1 1 1 Glucodextranase, domain N Glyco_hydro_15 PF00723.21 EHT98072.1 - 4.3e-08 32.4 0.1 0.0014 17.5 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 15 DDE_Tnp_1 PF01609.21 EHT98074.1 - 2.8e-20 72.9 0.0 6.1e-20 71.8 0.0 1.5 1 1 0 1 1 1 1 Transposase DDE domain Glyco_hydro_15 PF00723.21 EHT98075.1 - 2.8e-06 26.4 0.0 5.9e-06 25.3 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 NAD_binding_2 PF03446.15 EHT98076.1 - 2.9e-38 131.5 0.0 4.3e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 6PGD PF00393.19 EHT98076.1 - 3.6e-22 79.1 0.6 3.6e-09 36.4 0.3 3.2 2 1 0 2 2 2 2 6-phosphogluconate dehydrogenase, C-terminal domain F420_oxidored PF03807.17 EHT98076.1 - 3.1e-05 24.5 0.0 6.4e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 EHT98076.1 - 0.00035 20.8 0.0 0.00058 20.1 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.18 EHT98076.1 - 0.0064 16.4 0.1 0.0095 15.8 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EHT98076.1 - 0.0069 16.0 0.1 0.011 15.4 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 EHT98076.1 - 0.041 13.2 0.0 0.061 12.7 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Gp_dh_N PF00044.24 EHT98076.1 - 0.05 13.9 0.1 0.12 12.7 0.1 1.6 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NAD_binding_11 PF14833.6 EHT98076.1 - 0.057 13.7 2.3 0.17 12.1 1.8 2.0 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase GFO_IDH_MocA PF01408.22 EHT98076.1 - 0.15 12.9 0.0 0.28 12.0 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold G6PD_C PF02781.16 EHT98077.1 - 5.9e-88 294.8 0.0 7.7e-88 294.4 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 EHT98077.1 - 4.7e-51 173.9 0.0 6.5e-51 173.5 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 EHT98077.1 - 0.14 13.0 0.0 0.29 11.9 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold ROK PF00480.20 EHT98078.1 - 5.5e-08 32.6 0.0 3.6e-06 26.7 0.1 2.1 2 0 0 2 2 2 2 ROK family CcdB PF01845.17 EHT98079.1 - 8.5e-22 77.3 0.0 9.4e-22 77.1 0.0 1.0 1 0 0 1 1 1 1 CcdB protein CcdA PF07362.12 EHT98080.1 - 6.3e-21 74.6 0.5 6.9e-21 74.5 0.5 1.0 1 0 0 1 1 1 1 Post-segregation antitoxin CcdA HATPase_c_2 PF13581.6 EHT98082.1 - 1.4e-15 57.4 0.0 1.5e-15 57.2 0.0 1.0 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 EHT98082.1 - 0.098 13.2 0.0 0.13 12.8 0.0 1.1 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1910 PF08928.10 EHT98082.1 - 0.15 12.1 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) DDE_Tnp_IS66 PF03050.14 EHT98083.1 - 2.7e-97 325.6 3.4 1.2e-96 323.5 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT98083.1 - 3.4e-16 59.1 0.1 1.3e-15 57.3 0.1 2.1 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT98083.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT98083.1 - 1.2e-11 45.2 9.0 2.6e-11 44.1 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Exonuc_VII_L PF02601.15 EHT98083.1 - 0.042 13.4 2.1 0.052 13.1 0.7 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit FUSC PF04632.12 EHT98083.1 - 0.049 12.2 7.0 0.078 11.5 7.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Phage_HK97_TLTM PF06120.11 EHT98083.1 - 0.054 12.7 1.5 0.11 11.7 1.5 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHT98083.1 - 0.15 12.4 3.6 0.93 9.9 0.3 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain UME PF08064.13 EHT98083.1 - 0.15 12.0 0.4 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain FAM184 PF15665.5 EHT98083.1 - 0.16 11.7 5.7 0.25 11.1 5.7 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B DHR10 PF18595.1 EHT98083.1 - 0.18 11.9 10.2 0.31 11.1 10.2 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Tho2 PF11262.8 EHT98083.1 - 0.2 10.9 0.3 0.32 10.2 0.3 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 LXG PF04740.12 EHT98083.1 - 0.21 11.3 2.2 0.8 9.4 0.3 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHT98083.1 - 0.23 11.2 10.2 0.38 10.5 10.2 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HHH_8 PF14716.6 EHT98083.1 - 0.28 11.6 3.7 0.55 10.6 1.8 2.4 2 1 0 2 2 2 0 Helix-hairpin-helix domain Zn-ribbon_8 PF09723.10 EHT98083.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain TSNAXIP1_N PF15739.5 EHT98083.1 - 0.47 10.9 3.2 0.99 9.8 3.2 1.5 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus TMPIT PF07851.13 EHT98083.1 - 1 8.5 2.7 1.6 7.9 2.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHT98083.1 - 3.6 7.1 7.2 9.3 5.7 7.2 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 SlyX PF04102.12 EHT98083.1 - 8.2 7.1 8.7 12 6.6 1.6 3.0 1 1 1 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHT98084.1 - 1.7e-39 133.8 0.0 2e-39 133.6 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHT98085.1 - 2.5e-07 30.9 0.0 3.5e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Transposase SpoIIE PF07228.12 EHT98086.1 - 4e-38 131.3 0.0 7e-38 130.5 0.0 1.4 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Response_reg PF00072.24 EHT98086.1 - 1.4e-27 96.0 0.0 2.8e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain PilZ PF07238.14 EHT98086.1 - 0.075 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 PilZ domain Glycos_transf_2 PF00535.26 EHT98088.1 - 2.2e-19 69.9 0.0 5.2e-19 68.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EHT98088.1 - 7.4e-13 48.9 0.3 3e-12 46.9 0.3 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EHT98088.1 - 2.1e-10 40.8 2.1 2.1e-10 40.8 2.1 3.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 EHT98088.1 - 4.9e-09 35.9 0.0 9.3e-08 31.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Peptidase_M56 PF05569.11 EHT98088.1 - 6.7 5.8 9.1 0.35 10.0 1.5 2.5 3 0 0 3 3 3 0 BlaR1 peptidase M56 DUF3131 PF11329.8 EHT98089.1 - 2.6e-87 293.3 0.8 3e-87 293.1 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3131) FlhE PF06366.13 EHT98089.1 - 0.086 12.8 0.1 1.6 8.8 0.0 2.7 3 0 0 3 3 3 0 Flagellar protein FlhE DUF3131 PF11329.8 EHT98090.1 - 1.1e-146 488.6 1.0 1.3e-146 488.4 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3131) DUF3131 PF11329.8 EHT98091.1 - 1e-113 380.2 0.3 1.2e-113 380.0 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3131) Response_reg PF00072.24 EHT98093.1 - 2.4e-41 140.4 0.1 1.9e-22 79.6 0.0 2.7 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 EHT98093.1 - 2.1e-32 112.0 0.0 4e-32 111.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EHT98093.1 - 4.5e-22 77.8 0.0 4.5e-22 77.8 0.0 3.9 4 1 0 4 4 4 1 His Kinase A (phospho-acceptor) domain PAS_7 PF12860.7 EHT98093.1 - 5.3e-15 55.6 0.0 1.2e-13 51.2 0.0 2.7 2 0 0 2 2 2 1 PAS fold Hpt PF01627.23 EHT98093.1 - 1.4e-11 44.5 2.7 5.2e-11 42.6 2.7 2.1 1 0 0 1 1 1 1 Hpt domain PAS_3 PF08447.12 EHT98093.1 - 2.6e-11 43.7 0.1 3.4e-10 40.1 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 EHT98093.1 - 0.0034 17.6 0.0 0.018 15.3 0.0 2.3 2 0 0 2 2 2 1 PAS domain FleQ PF06490.11 EHT98093.1 - 0.0037 17.6 0.2 0.58 10.5 0.0 3.1 3 0 0 3 3 3 1 Flagellar regulatory protein FleQ PAS PF00989.25 EHT98093.1 - 0.008 16.2 0.8 0.14 12.2 0.3 2.9 2 1 0 2 2 2 1 PAS fold PAS_4 PF08448.10 EHT98093.1 - 0.03 14.6 0.3 0.43 10.8 0.2 2.9 2 0 0 2 2 2 0 PAS fold HATPase_c_3 PF13589.6 EHT98093.1 - 0.16 11.8 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glyco_hydro_2 PF00703.21 EHT98094.1 - 9.9e-11 42.3 0.0 7.1e-10 39.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 EHT98094.1 - 3.1e-07 29.8 0.4 3.6e-06 26.3 0.4 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 EHT98094.1 - 1e-06 28.8 0.0 2.8e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Mannosidase_ig PF17786.1 EHT98094.1 - 1.7e-05 25.3 0.0 3.9e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain BetaGal_dom4_5 PF13364.6 EHT98094.1 - 0.049 14.2 0.0 0.14 12.8 0.0 1.8 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain Xan_ur_permease PF00860.20 EHT98095.1 - 2.9e-96 322.5 56.5 2.9e-96 322.5 56.5 1.5 1 1 1 2 2 2 1 Permease family Tom5 PF10642.9 EHT98095.1 - 1.9 8.6 3.9 2.6 8.2 0.3 2.9 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase Flavin_Reduct PF01613.18 EHT98096.1 - 3e-31 108.6 0.2 3.6e-31 108.3 0.2 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Vma12 PF11712.8 EHT98096.1 - 0.15 12.1 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Nitroreductase PF00881.24 EHT98097.1 - 5.7e-18 65.5 0.0 2.7e-17 63.3 0.0 1.8 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 EHT98097.1 - 0.11 12.0 0.0 4.9 6.7 0.0 2.0 2 0 0 2 2 2 0 Putative TM nitroreductase Abhydrolase_1 PF00561.20 EHT98098.1 - 5.5e-15 55.7 0.3 2.7e-11 43.6 0.4 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EHT98098.1 - 2.8e-14 54.3 5.2 3.4e-14 54.0 5.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EHT98098.1 - 4.9e-13 48.9 0.3 6.2e-13 48.6 0.3 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EHT98098.1 - 0.00074 19.4 0.0 0.0097 15.7 0.0 2.2 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Thioesterase PF00975.20 EHT98098.1 - 0.0013 18.9 0.2 0.0025 18.0 0.2 1.7 1 1 0 1 1 1 1 Thioesterase domain Ndr PF03096.14 EHT98098.1 - 0.0029 16.3 0.0 0.0037 16.0 0.0 1.1 1 0 0 1 1 1 1 Ndr family Esterase PF00756.20 EHT98098.1 - 0.065 12.9 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Ribonuc_L-PSP PF01042.21 EHT98099.1 - 2.3e-31 108.3 0.0 2.7e-31 108.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Isochorismatase PF00857.20 EHT98100.1 - 4.7e-40 137.6 0.0 6.6e-40 137.1 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Bac_luciferase PF00296.20 EHT98101.1 - 4.5e-70 236.6 0.4 5.6e-70 236.3 0.4 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Copine PF07002.16 EHT98101.1 - 0.047 13.1 0.0 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 Copine TetR_C_3 PF08362.11 EHT98102.1 - 5.7e-55 185.2 0.0 7.1e-55 184.9 0.0 1.1 1 0 0 1 1 1 1 YcdC-like protein, C-terminal region TetR_N PF00440.23 EHT98102.1 - 3.7e-14 52.3 0.1 6.2e-14 51.5 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_29 PF17938.1 EHT98102.1 - 0.0052 16.9 0.0 0.0097 16.0 0.0 1.5 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain ABC_tran PF00005.27 EHT98103.1 - 1.7e-36 125.8 0.0 2.4e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EHT98103.1 - 1.1e-12 48.4 0.0 5.8e-06 26.3 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EHT98103.1 - 9.4e-11 41.6 0.1 3.7e-10 39.6 0.1 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EHT98103.1 - 0.00012 22.5 0.2 0.00029 21.2 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EHT98103.1 - 0.00029 20.5 0.0 0.00058 19.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 EHT98103.1 - 0.00051 19.8 0.3 0.0031 17.2 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EHT98103.1 - 0.00061 20.1 0.2 0.0035 17.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EHT98103.1 - 0.00072 19.4 0.0 0.032 13.9 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EHT98103.1 - 0.001 19.0 0.1 0.0023 17.9 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 EHT98103.1 - 0.0011 19.6 0.0 0.0025 18.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_13 PF13166.6 EHT98103.1 - 0.0013 17.5 0.0 0.036 12.7 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 EHT98103.1 - 0.0047 17.1 0.1 0.0096 16.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EHT98103.1 - 0.018 15.5 0.0 1.5 9.3 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EHT98103.1 - 0.027 14.1 0.0 0.16 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EHT98103.1 - 0.034 14.1 0.0 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_ATPase PF09818.9 EHT98103.1 - 0.036 12.9 0.1 3.9 6.1 0.0 2.8 2 1 0 2 2 2 0 Predicted ATPase of the ABC class NB-ARC PF00931.22 EHT98103.1 - 0.038 13.2 0.2 0.13 11.5 0.2 1.9 1 1 0 1 1 1 0 NB-ARC domain IstB_IS21 PF01695.17 EHT98103.1 - 0.044 13.5 0.0 0.096 12.4 0.0 1.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.6 EHT98103.1 - 0.048 14.2 0.2 0.09 13.3 0.2 1.6 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 EHT98103.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain SbcCD_C PF13558.6 EHT98103.1 - 0.11 12.8 0.1 1.4 9.2 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 EHT98103.1 - 0.11 12.1 0.1 0.29 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain BPD_transp_1 PF00528.22 EHT98104.1 - 1.9e-23 83.2 10.0 2.5e-23 82.8 10.0 1.2 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component DUF2534 PF10749.9 EHT98104.1 - 0.0022 18.1 0.3 0.0086 16.2 0.3 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2534) SBP_bac_3 PF00497.20 EHT98105.1 - 1.1e-55 188.5 0.1 1.3e-55 188.3 0.1 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 EHT98105.1 - 2.7e-07 30.8 0.0 1.2e-05 25.4 0.0 2.4 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Cupin_2 PF07883.11 EHT98106.1 - 6e-14 51.5 0.1 1.2e-13 50.5 0.0 1.6 2 0 0 2 2 2 1 Cupin domain HTH_3 PF01381.22 EHT98106.1 - 2.2e-13 50.0 0.1 3.8e-13 49.3 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EHT98106.1 - 5.8e-10 39.4 0.2 5.7e-09 36.2 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 EHT98106.1 - 1.9e-09 37.4 0.2 2.9e-09 36.8 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 EHT98106.1 - 0.00054 20.3 0.0 0.00086 19.7 0.0 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 EHT98106.1 - 0.0016 18.2 0.2 0.0035 17.2 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 EHT98106.1 - 0.002 17.6 0.1 0.0076 15.7 0.1 2.0 1 0 0 1 1 1 1 Sigma-70, region 4 AraC_binding PF02311.19 EHT98106.1 - 0.031 14.2 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 AraC-like ligand binding domain MarR PF01047.22 EHT98106.1 - 0.036 14.0 0.1 0.077 12.9 0.1 1.6 1 0 0 1 1 1 0 MarR family CENP-C_C PF11699.8 EHT98106.1 - 0.062 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Mif2/CENP-C like HTH_24 PF13412.6 EHT98106.1 - 0.082 12.5 0.3 0.14 11.7 0.3 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_6 PF01418.17 EHT98106.1 - 0.09 12.8 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family Cupin_3 PF05899.12 EHT98106.1 - 0.092 12.4 0.0 0.38 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF861) TetR_N PF00440.23 EHT98106.1 - 0.16 11.8 0.1 0.33 10.8 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family DAO PF01266.24 EHT98107.1 - 2.6e-68 231.2 0.5 3.5e-68 230.8 0.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EHT98107.1 - 1.1e-07 32.0 0.2 1.5e-06 28.3 0.1 2.8 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EHT98107.1 - 5e-07 29.2 7.1 2.9e-05 23.4 7.1 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EHT98107.1 - 6.1e-05 22.4 0.1 0.00012 21.4 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EHT98107.1 - 6.9e-05 22.1 0.1 0.00013 21.2 0.1 1.4 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EHT98107.1 - 0.00011 21.6 2.3 0.00091 18.6 1.6 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 EHT98107.1 - 0.00016 21.0 1.8 0.00019 20.7 0.5 1.7 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 EHT98107.1 - 0.00032 20.2 0.1 0.0005 19.5 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EHT98107.1 - 0.0051 15.6 4.5 0.0099 14.6 1.0 2.5 3 0 0 3 3 3 1 HI0933-like protein Lycopene_cycl PF05834.12 EHT98107.1 - 0.009 15.1 0.1 0.015 14.4 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein 3HCDH_N PF02737.18 EHT98107.1 - 0.034 14.0 0.2 0.058 13.3 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 EHT98107.1 - 0.036 13.3 0.0 0.12 11.5 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EHT98107.1 - 0.046 14.2 0.0 0.079 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.27 EHT98107.1 - 0.047 14.2 2.4 0.12 13.0 2.4 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EHT98107.1 - 0.078 12.3 0.3 0.13 11.5 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 EHT98107.1 - 0.23 11.1 0.5 0.39 10.4 0.5 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA KTSC PF13619.6 EHT98108.1 - 3.6e-17 61.9 0.0 4.2e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 KTSC domain DDE_3 PF13358.6 EHT98109.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHT98109.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHT98109.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHT98109.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHT98109.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHT98109.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHT98109.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHT98109.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 Flagellin_N PF00669.20 EHT98110.1 - 3.6e-39 134.0 17.6 3.6e-39 134.0 17.6 2.8 2 1 1 3 3 3 1 Bacterial flagellin N-terminal helical region Flagellin_C PF00700.21 EHT98110.1 - 8.9e-30 102.9 23.9 1.1e-29 102.6 8.1 4.3 2 1 2 4 4 4 2 Bacterial flagellin C-terminal helical region Snapin_Pallidin PF14712.6 EHT98110.1 - 0.021 15.2 4.9 5.8 7.4 0.1 3.4 3 1 0 3 3 3 0 Snapin/Pallidin DUF745 PF05335.13 EHT98110.1 - 0.035 13.8 4.7 0.67 9.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF745) HAUS-augmin3 PF14932.6 EHT98110.1 - 0.31 10.6 3.3 0.91 9.1 0.2 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF948 PF06103.11 EHT98110.1 - 7.8 6.8 8.8 12 6.3 2.6 3.6 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) FMN_red PF03358.15 EHT98111.1 - 1.1e-38 132.4 0.0 1.6e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EHT98111.1 - 2.3e-07 30.8 0.0 2.5e-07 30.6 0.0 1.3 1 1 0 1 1 1 1 Flavodoxin-like fold DUF333 PF03891.15 EHT98112.1 - 3.2e-20 72.1 0.0 3.8e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF333) Lactamase_B PF00753.27 EHT98114.1 - 7.4e-05 22.8 0.4 0.00017 21.7 0.4 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Glyco_hydro_1 PF00232.18 EHT98115.1 - 3.9e-152 506.8 0.0 4.3e-152 506.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.18 EHT98115.1 - 0.00012 21.6 0.0 0.00029 20.4 0.0 1.5 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.6 EHT98115.1 - 0.042 13.5 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) PTS_EIIA_1 PF00358.20 EHT98116.1 - 2.2e-48 163.2 0.1 3.5e-48 162.6 0.1 1.3 1 0 0 1 1 1 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 PTS_EIIC PF02378.18 EHT98116.1 - 3.4e-27 95.3 27.6 3.4e-27 95.3 27.6 1.7 2 0 0 2 2 2 1 Phosphotransferase system, EIIC PTS_EIIB PF00367.20 EHT98116.1 - 5.7e-14 51.3 0.1 9.8e-14 50.6 0.1 1.4 1 0 0 1 1 1 1 phosphotransferase system, EIIB Biotin_lipoyl_2 PF13533.6 EHT98116.1 - 0.062 13.1 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Biotin-lipoyl like PRD PF00874.20 EHT98117.1 - 1.9e-18 66.5 0.5 2.3e-18 66.3 0.5 1.0 1 0 0 1 1 1 1 PRD domain HTH_Tnp_1 PF01527.20 EHT98118.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT98118.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT98118.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT98118.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHT98119.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHT98120.1 - 1.1e-97 326.9 4.5 3.8e-97 325.1 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT98120.1 - 3.2e-16 59.3 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT98120.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT98120.1 - 8.7e-11 42.4 9.0 1.9e-10 41.4 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Phage_HK97_TLTM PF06120.11 EHT98120.1 - 0.011 15.0 0.8 0.021 14.0 0.8 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHT98120.1 - 0.02 15.2 4.2 0.084 13.2 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain UME PF08064.13 EHT98120.1 - 0.033 14.1 0.3 20 5.1 0.0 3.1 2 1 1 3 3 3 0 UME (NUC010) domain Exonuc_VII_L PF02601.15 EHT98120.1 - 0.039 13.5 2.7 0.04 13.5 1.0 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Troponin PF00992.20 EHT98120.1 - 0.044 14.1 2.8 0.078 13.3 2.8 1.3 1 0 0 1 1 1 0 Troponin FUSC PF04632.12 EHT98120.1 - 0.048 12.2 7.4 0.077 11.5 7.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tho2 PF11262.8 EHT98120.1 - 0.049 12.8 0.6 0.081 12.1 0.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FAM184 PF15665.5 EHT98120.1 - 0.052 13.3 8.0 0.082 12.7 8.0 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B HalX PF08663.10 EHT98120.1 - 0.13 12.6 2.4 0.34 11.3 2.4 1.7 1 0 0 1 1 1 0 HalX domain LXG PF04740.12 EHT98120.1 - 0.14 11.8 2.8 0.35 10.5 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHT98120.1 - 0.19 11.5 11.1 0.31 10.8 11.1 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DHR10 PF18595.1 EHT98120.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Zn-ribbon_8 PF09723.10 EHT98120.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF1192 PF06698.11 EHT98120.1 - 0.54 10.4 5.3 3.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHT98120.1 - 0.82 8.9 3.0 1.2 8.3 3.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHT98120.1 - 2 8.0 8.1 4.3 6.8 8.1 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHT98120.1 - 4.2 7.7 8.6 8.7 6.7 8.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CREPT PF16566.5 EHT98120.1 - 5.9 7.1 8.7 2.7 8.1 5.6 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour SlyX PF04102.12 EHT98120.1 - 9.3 7.0 9.0 18 6.1 2.3 3.0 1 1 1 2 2 2 0 SlyX CAT_RBD PF03123.15 EHT98121.1 - 5.4e-22 77.5 0.1 8.8e-22 76.8 0.1 1.3 1 0 0 1 1 1 1 CAT RNA binding domain PRD PF00874.20 EHT98121.1 - 7.5e-20 71.0 0.0 1.6e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 PRD domain OprB PF04966.12 EHT98122.1 - 5.2e-57 194.0 6.7 6.1e-57 193.7 6.7 1.0 1 0 0 1 1 1 1 Carbohydrate-selective porin, OprB family CM_2 PF01817.21 EHT98123.1 - 6.8e-16 58.4 2.9 4.7e-13 49.3 0.1 2.2 2 0 0 2 2 2 2 Chorismate mutase type II Plasmid_RAQPRD PF09686.10 EHT98123.1 - 0.21 11.8 3.7 0.29 11.4 2.0 2.0 2 1 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DUF2730 PF10805.8 EHT98123.1 - 0.25 11.4 2.7 2.7 8.1 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) MCPsignal PF00015.21 EHT98124.1 - 4.5e-52 176.3 18.2 4.5e-52 176.3 18.2 3.5 3 1 0 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 EHT98124.1 - 1.1e-10 41.8 4.1 1.1e-08 35.3 0.3 4.3 3 0 0 3 3 3 1 HAMP domain Sec5 PF15469.6 EHT98124.1 - 0.015 15.1 2.3 0.03 14.1 0.3 2.5 2 0 0 2 2 2 0 Exocyst complex component Sec5 3H PF02829.14 EHT98124.1 - 0.31 11.3 1.8 3.7 7.9 0.1 3.4 4 0 0 4 4 4 0 3H domain Seryl_tRNA_N PF02403.22 EHT98124.1 - 1.2 9.3 10.6 0.31 11.3 2.1 3.6 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Multi_Drug_Res PF00893.19 EHT98125.1 - 4.1e-05 24.2 6.0 0.00012 22.7 6.0 1.7 1 1 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 EHT98125.1 - 0.00027 21.1 14.0 0.0035 17.5 14.3 1.9 1 1 0 1 1 1 1 EamA-like transporter family SLATT_1 PF18181.1 EHT98125.1 - 0.088 12.7 0.4 0.14 12.1 0.2 1.5 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 EamA PF00892.20 EHT98126.1 - 1.7e-11 44.4 10.1 2e-11 44.2 10.1 1.1 1 0 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 EHT98126.1 - 9.4e-06 25.6 0.6 1.1e-05 25.4 0.5 1.2 1 1 0 1 1 1 1 Putative transmembrane family 234 Multi_Drug_Res PF00893.19 EHT98126.1 - 4e-05 24.2 3.6 5.1e-05 23.9 3.6 1.1 1 0 0 1 1 1 1 Small Multidrug Resistance protein DUF4010 PF13194.6 EHT98126.1 - 0.0045 16.7 7.0 0.0053 16.5 7.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4010) Mg_trans_NIPA PF05653.14 EHT98126.1 - 0.0062 15.7 3.7 0.0065 15.6 3.7 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA TPT PF03151.16 EHT98126.1 - 0.0065 15.8 1.4 0.0068 15.8 1.4 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family DUF5345 PF17280.2 EHT98126.1 - 0.12 12.4 0.3 0.12 12.4 0.3 2.2 3 1 0 3 3 3 0 Family of unknown function (DUF5345) VirB8 PF04335.13 EHT98126.1 - 2.3 8.0 5.7 0.32 10.8 1.6 1.6 2 0 0 2 2 2 0 VirB8 protein DUF4131 PF13567.6 EHT98126.1 - 3.3 7.4 15.4 0.42 10.2 6.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF202 PF02656.15 EHT98126.1 - 6.6 7.2 14.4 11 6.5 3.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF202) PMT PF02366.18 EHT98127.1 - 4.8e-38 131.1 15.1 4.8e-38 131.1 15.1 2.4 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_2 PF13231.6 EHT98127.1 - 1.9e-16 60.7 17.0 1.9e-16 60.7 17.0 3.0 4 0 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Polysacc_deac_1 PF01522.21 EHT98128.1 - 1.1e-09 38.2 0.0 1.9e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Epimerase PF01370.21 EHT98129.1 - 1.1e-43 149.5 0.0 1.6e-43 148.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EHT98129.1 - 9.7e-26 90.9 0.0 1.3e-25 90.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Formyl_trans_N PF00551.19 EHT98129.1 - 1.1e-24 87.2 0.0 1.7e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 EHT98129.1 - 4e-21 75.1 0.0 1.3e-20 73.5 0.0 1.8 2 0 0 2 2 2 1 Formyl transferase, C-terminal domain 3Beta_HSD PF01073.19 EHT98129.1 - 5.3e-05 22.4 0.0 7.7e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EHT98129.1 - 0.00015 21.7 0.0 0.00029 20.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EHT98129.1 - 0.015 14.5 0.0 5.3 6.1 0.1 2.4 2 0 0 2 2 2 0 Male sterility protein RmlD_sub_bind PF04321.17 EHT98129.1 - 0.045 12.8 0.0 0.079 12.1 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Glycos_transf_2 PF00535.26 EHT98130.1 - 4e-31 108.1 0.0 5.5e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EHT98130.1 - 9.3e-13 48.6 0.1 1.9e-12 47.6 0.1 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EHT98130.1 - 0.00039 20.0 0.0 0.00057 19.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 EHT98130.1 - 0.2 12.2 0.4 0.64 10.6 0.1 2.1 2 1 0 2 2 2 0 Glycosyl transferase family 2 DegT_DnrJ_EryC1 PF01041.17 EHT98131.1 - 1.5e-131 439.0 0.0 1.7e-131 438.8 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EHT98131.1 - 6.4e-09 34.8 0.1 9.7e-09 34.2 0.1 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EHT98131.1 - 3.2e-08 33.1 0.0 6.4e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EHT98131.1 - 1.7e-05 24.3 1.2 4.1e-05 23.0 1.2 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 EHT98131.1 - 0.094 11.4 0.2 0.2 10.4 0.2 1.5 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain A-2_8-polyST PF07388.11 EHT98132.1 - 0.1 11.2 0.0 0.1 11.2 0.0 1.0 1 0 0 1 1 1 0 Alpha-2,8-polysialyltransferase (POLYST) ABM PF03992.16 EHT98133.1 - 0.0023 18.0 0.4 0.003 17.7 0.4 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF4188 PF13826.6 EHT98133.1 - 0.037 14.4 0.1 0.076 13.4 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4188) DUF1416 PF07210.12 EHT98133.1 - 0.058 13.3 0.2 0.072 13.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) DNase_II PF03265.15 EHT98134.1 - 0.021 14.1 0.1 0.021 14.1 0.1 1.0 1 0 0 1 1 1 0 Deoxyribonuclease II Ribosomal_L5_C PF00673.21 EHT98134.1 - 0.055 13.7 0.0 0.074 13.2 0.0 1.2 1 0 0 1 1 1 0 ribosomal L5P family C-terminus Response_reg PF00072.24 EHT98135.1 - 1.1e-26 93.2 0.0 1.8e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 EHT98135.1 - 5.4e-18 64.8 0.0 1.6e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal B12-binding PF02310.19 EHT98135.1 - 0.076 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 B12 binding domain DUF1507 PF07408.11 EHT98135.1 - 0.091 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1507) HATPase_c PF02518.26 EHT98136.1 - 1.1e-19 70.9 0.0 2.1e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EHT98136.1 - 7.8e-05 22.6 0.1 0.00018 21.5 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 EHT98136.1 - 0.17 11.8 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain HlyD_D23 PF16576.5 EHT98137.1 - 8.4e-19 67.6 0.7 1.7e-18 66.7 0.7 1.4 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 EHT98137.1 - 8.9e-15 55.3 0.4 2.5e-12 47.4 0.1 2.4 2 0 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 EHT98137.1 - 1.2e-12 47.5 4.9 2.5e-09 36.8 0.2 2.7 2 1 0 2 2 2 2 Biotin-lipoyl like Biotin_lipoyl PF00364.22 EHT98137.1 - 1.5e-05 24.7 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 2 Biotin-requiring enzyme ACR_tran PF00873.19 EHT98138.1 - 2.3e-155 518.9 9.4 3e-155 518.5 9.4 1.1 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MCPsignal PF00015.21 EHT98139.1 - 4.9e-48 163.2 19.0 4.9e-48 163.2 19.0 4.3 3 1 2 5 5 5 2 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.7 EHT98139.1 - 1.4e-12 47.6 6.3 1.4e-12 47.6 6.3 4.0 3 2 0 3 3 3 1 Four helix bundle sensory module for signal transduction HAMP PF00672.25 EHT98139.1 - 2.9e-09 37.2 0.4 1.2e-07 32.0 0.1 3.6 3 0 0 3 3 3 1 HAMP domain TarH PF02203.15 EHT98139.1 - 6.4e-08 32.7 4.2 6.4e-08 32.7 4.2 4.4 3 2 2 5 5 5 1 Tar ligand binding domain homologue DUF948 PF06103.11 EHT98139.1 - 0.0093 16.2 31.5 0.17 12.2 0.7 5.9 2 1 4 6 6 6 3 Bacterial protein of unknown function (DUF948) Mobilization_B PF17511.2 EHT98139.1 - 0.017 15.5 1.7 0.017 15.5 1.7 3.7 3 1 1 4 4 4 0 Mobilization protein B Mce4_CUP1 PF11887.8 EHT98139.1 - 0.44 10.0 13.6 0.54 9.7 1.9 2.4 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative CLZ PF16526.5 EHT98139.1 - 0.84 10.0 3.6 40 4.7 1.6 3.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Prominin PF05478.11 EHT98139.1 - 1.2 7.0 19.0 0.034 12.1 3.0 3.0 1 1 2 3 3 3 0 Prominin Peptidase_M9_N PF08453.10 EHT98139.1 - 1.6 8.4 12.4 0.25 11.0 0.4 3.6 3 1 0 3 3 3 0 Peptidase family M9 N-terminal DUF1664 PF07889.12 EHT98139.1 - 1.9 8.6 20.1 0.05 13.6 4.2 4.2 3 2 2 5 5 5 0 Protein of unknown function (DUF1664) DUF4455 PF14643.6 EHT98139.1 - 2.2 6.8 8.9 0.13 10.9 0.7 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4455) GGACT PF06094.12 EHT98140.1 - 0.00071 20.2 0.0 0.00071 20.2 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 EHT98140.1 - 0.11 13.0 0.0 0.11 13.0 0.0 1.0 1 0 0 1 1 1 0 AIG2-like family EamA PF00892.20 EHT98141.1 - 4e-28 98.3 44.1 1.9e-16 60.5 17.1 2.1 2 0 0 2 2 2 2 EamA-like transporter family SLAC1 PF03595.17 EHT98141.1 - 0.00047 19.5 20.1 0.00047 19.5 20.1 2.1 2 0 0 2 2 2 1 Voltage-dependent anion channel DDE_3 PF13358.6 EHT98142.1 - 1.1e-22 80.3 0.0 1.9e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 EHT98142.1 - 1.1e-10 41.0 1.0 3.6e-09 36.2 0.1 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 EHT98142.1 - 4.1e-09 36.9 1.1 2.8e-08 34.3 0.3 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 EHT98142.1 - 4e-07 30.0 1.2 1.1e-06 28.6 0.3 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHT98142.1 - 1.4e-05 25.1 0.3 0.0002 21.4 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_33 PF13592.6 EHT98142.1 - 6e-05 22.6 5.4 8.3e-05 22.1 0.5 3.0 3 0 0 3 3 3 1 Winged helix-turn helix LZ_Tnp_IS481 PF13011.6 EHT98142.1 - 0.029 14.9 0.2 0.061 13.8 0.2 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 HTH_38 PF13936.6 EHT98142.1 - 0.052 13.3 0.6 0.16 11.8 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_18 PF12833.7 EHT98143.1 - 1.3e-23 83.1 0.9 2.5e-23 82.2 0.9 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 EHT98143.1 - 5.8e-19 67.7 0.2 3.6e-10 39.7 0.1 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Abhydrolase_3 PF07859.13 EHT98145.1 - 1.9e-23 83.5 0.4 2.7e-23 83.0 0.4 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EHT98145.1 - 9.2e-19 67.8 2.1 4.9e-13 49.1 0.0 3.0 2 1 1 3 3 3 2 Prolyl oligopeptidase family COesterase PF00135.28 EHT98145.1 - 6.8e-09 35.1 0.1 2.9e-08 33.0 0.1 1.8 1 1 0 1 1 1 1 Carboxylesterase family Hydrolase_4 PF12146.8 EHT98145.1 - 2.2e-05 23.9 0.5 0.00044 19.6 0.0 2.4 2 1 0 2 2 2 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 EHT98145.1 - 3.3e-05 23.9 0.1 0.21 11.5 0.0 2.3 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 EHT98145.1 - 7.5e-05 22.4 1.4 0.052 13.1 0.2 3.1 1 1 1 2 2 2 2 Dienelactone hydrolase family Esterase_phd PF10503.9 EHT98145.1 - 7.9e-05 22.3 0.2 0.41 10.1 0.0 2.4 2 0 0 2 2 2 2 Esterase PHB depolymerase LIP PF03583.14 EHT98145.1 - 0.00085 18.7 0.1 0.089 12.1 0.0 2.3 2 0 0 2 2 2 1 Secretory lipase FSH1 PF03959.13 EHT98145.1 - 0.0053 16.4 0.0 0.025 14.3 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 EHT98145.1 - 0.015 14.9 0.1 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold AXE1 PF05448.12 EHT98145.1 - 0.18 10.4 0.2 1.6 7.3 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Mannitol_dh_C PF08125.13 EHT98146.1 - 3.6e-90 301.7 0.0 4.8e-90 301.4 0.0 1.1 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 EHT98146.1 - 5.8e-48 162.9 0.0 1.2e-47 161.9 0.0 1.5 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain PdxA PF04166.12 EHT98147.1 - 1.3e-102 343.0 0.3 1.5e-102 342.8 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA Iso_dh PF00180.20 EHT98147.1 - 0.013 14.6 0.0 0.082 12.0 0.0 2.0 2 0 0 2 2 2 0 Isocitrate/isopropylmalate dehydrogenase Fe-ADH PF00465.19 EHT98148.1 - 6.8e-94 314.7 0.9 7.6e-94 314.5 0.9 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EHT98148.1 - 6.6e-15 55.5 1.2 7.8e-11 42.1 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase DHDPS PF00701.22 EHT98149.1 - 4.4e-63 212.7 0.0 5.3e-63 212.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Exonuc_VIII PF06630.11 EHT98149.1 - 0.18 11.6 0.0 0.56 10.0 0.0 1.8 2 0 0 2 2 2 0 Enterobacterial exodeoxyribonuclease VIII SSF PF00474.17 EHT98150.1 - 1.8e-25 89.7 34.3 4.3e-25 88.4 34.3 1.6 1 1 0 1 1 1 1 Sodium:solute symporter family BNR_2 PF13088.6 EHT98151.1 - 1.4e-65 221.3 1.4 1.7e-65 221.1 1.4 1.0 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 EHT98151.1 - 7.6e-06 25.2 14.6 0.24 11.5 0.7 4.9 4 0 0 4 4 4 3 BNR/Asp-box repeat BNR_4 PF15892.5 EHT98151.1 - 8.2e-05 22.1 0.0 1.2 8.5 0.0 3.2 2 1 1 3 3 3 2 BNR repeat-containing family member Sortilin-Vps10 PF15902.5 EHT98151.1 - 0.00011 21.1 0.0 0.004 16.0 0.0 2.5 2 1 0 2 2 2 1 Sortilin, neurotensin receptor 3, PSII_BNR PF14870.6 EHT98151.1 - 0.031 13.5 0.5 0.6 9.3 0.1 2.5 2 1 0 2 2 2 0 Photosynthesis system II assembly factor YCF48 Mo-co_dimer PF03404.16 EHT98151.1 - 0.056 13.5 2.3 15 5.6 0.1 3.3 2 1 0 3 3 3 0 Mo-co oxidoreductase dimerisation domain DUF386 PF04074.12 EHT98152.1 - 2e-27 95.9 0.0 2.3e-27 95.7 0.0 1.0 1 0 0 1 1 1 1 YhcH/YjgK/YiaL Cupin_2 PF07883.11 EHT98152.1 - 0.085 12.6 0.1 0.46 10.2 0.0 1.9 2 0 0 2 2 2 0 Cupin domain adh_short_C2 PF13561.6 EHT98153.1 - 2.5e-37 128.7 0.0 3.4e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EHT98153.1 - 4.3e-31 107.9 0.1 5.7e-31 107.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 EHT98153.1 - 6.7e-11 42.1 0.1 6.7e-09 35.6 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.10 EHT98153.1 - 2e-06 27.8 0.6 6.9e-06 26.1 0.6 1.7 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EHT98153.1 - 2e-05 24.6 0.1 2.2e-05 24.4 0.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EHT98153.1 - 0.00091 18.4 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EHT98153.1 - 0.015 14.7 0.1 0.092 12.1 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DFP PF04127.15 EHT98153.1 - 0.045 13.6 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein DDE_Tnp_1 PF01609.21 EHT98154.1 - 5.5e-20 71.9 0.0 1e-19 71.0 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain Cupin_2 PF07883.11 EHT98155.1 - 4.9e-06 26.2 0.0 6.7e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_7 PF12973.7 EHT98155.1 - 0.0004 20.2 0.0 0.00069 19.5 0.0 1.4 1 0 0 1 1 1 1 ChrR Cupin-like domain ANT PF03374.14 EHT98156.1 - 6e-24 84.4 0.4 1.5e-23 83.2 0.1 1.7 2 0 0 2 2 2 1 Phage antirepressor protein KilAC domain Phage_pRha PF09669.10 EHT98156.1 - 8.1e-12 45.5 0.0 1.7e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Phage regulatory protein Rha (Phage_pRha) HTH_Crp_2 PF13545.6 EHT98156.1 - 0.097 12.7 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain DMRL_synthase PF00885.19 EHT98157.1 - 8.4e-34 116.4 0.0 9.4e-34 116.3 0.0 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase DUF1348 PF07080.11 EHT98158.1 - 2.1e-63 212.1 5.0 2.4e-63 211.9 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 EHT98158.1 - 1.3e-05 25.8 0.4 2.6e-05 24.8 0.3 1.6 1 1 1 2 2 2 1 SnoaL-like domain DUF4440 PF14534.6 EHT98158.1 - 0.00078 19.8 0.1 0.002 18.5 0.1 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4440) DUF2604 PF10790.9 EHT98158.1 - 0.011 16.1 0.1 0.019 15.2 0.1 1.4 1 0 0 1 1 1 0 Protein of Unknown function (DUF2604) BAT PF15915.5 EHT98159.1 - 0.058 13.3 0.1 0.11 12.3 0.0 1.4 1 1 0 1 1 1 0 GAF and HTH_10 associated domain DUF2846 PF11008.8 EHT98159.1 - 0.072 13.1 0.0 0.09 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2846) adh_short_C2 PF13561.6 EHT98160.1 - 1.6e-21 76.9 0.0 2.4e-21 76.4 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EHT98160.1 - 2.3e-07 30.5 0.0 2.9e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase HTH_Tnp_1 PF01527.20 EHT98161.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT98161.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT98161.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT98161.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHT98162.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein MCPsignal PF00015.21 EHT98164.1 - 1.4e-40 139.0 11.7 1.4e-40 139.0 11.7 2.7 2 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain dCache_1 PF02743.18 EHT98164.1 - 1.2e-20 74.4 0.5 1.2e-20 74.4 0.5 2.7 2 1 0 2 2 2 1 Cache domain TMF_TATA_bd PF12325.8 EHT98164.1 - 0.12 12.5 4.0 1.5 9.1 1.0 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF948 PF06103.11 EHT98164.1 - 0.21 11.8 10.4 1.3 9.3 3.1 3.5 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Snf7 PF03357.21 EHT98164.1 - 6.4 6.3 12.0 0.15 11.7 4.8 1.8 2 0 0 2 2 2 0 Snf7 Cupin_2 PF07883.11 EHT98165.1 - 3.2e-16 58.8 0.2 4.7e-16 58.3 0.2 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EHT98165.1 - 0.00056 19.8 0.4 0.00083 19.3 0.4 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain FdtA PF05523.11 EHT98165.1 - 0.012 15.3 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 WxcM-like, C-terminal CENP-C_C PF11699.8 EHT98165.1 - 0.021 15.0 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 Mif2/CENP-C like MannoseP_isomer PF01050.18 EHT98165.1 - 0.022 14.7 0.3 0.023 14.6 0.3 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Cupin_1 PF00190.22 EHT98165.1 - 0.11 12.1 0.1 0.26 10.9 0.1 1.6 1 1 0 1 1 1 0 Cupin YebG PF07130.12 EHT98167.1 - 1.3e-32 111.5 4.5 1.8e-32 111.0 4.5 1.2 1 0 0 1 1 1 1 YebG protein DEP PF00610.21 EHT98167.1 - 0.0094 16.0 0.1 0.012 15.6 0.1 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) SIR2_2 PF13289.6 EHT98168.1 - 5.4e-25 88.2 0.1 1.1e-24 87.2 0.1 1.5 2 0 0 2 2 2 1 SIR2-like domain Ham1p_like PF01725.16 EHT98169.1 - 1.6e-33 116.2 0.0 1.8e-33 116.0 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Histone_HNS PF00816.21 EHT98171.1 - 1.1e-19 71.0 3.0 1.1e-19 71.0 3.0 1.4 1 1 0 1 1 1 1 H-NS histone family SidE PF12252.8 EHT98171.1 - 0.012 13.2 0.7 0.014 13.0 0.7 1.0 1 0 0 1 1 1 0 Dot/Icm substrate protein PdxJ PF03740.13 EHT98171.1 - 0.046 12.8 0.1 0.047 12.8 0.1 1.1 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthesis protein PdxJ Phage_integrase PF00589.22 EHT98172.1 - 9.6e-11 41.8 0.0 3.9e-10 39.8 0.0 1.9 2 0 0 2 2 2 1 Phage integrase family Ribosomal_S7 PF00177.21 EHT98172.1 - 0.11 12.2 0.0 4.2 7.0 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein S7p/S5e DUF2309 PF10070.9 EHT98175.1 - 2.4e-252 839.6 3.6 2.7e-252 839.4 3.6 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2309) HARE-HTH PF05066.13 EHT98175.1 - 0.17 12.3 0.7 0.38 11.2 0.7 1.5 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain Proton_antipo_M PF00361.20 EHT98176.1 - 3.7e-37 128.1 28.4 3.7e-37 128.1 28.4 3.0 2 1 1 3 3 3 1 Proton-conducting membrane transporter HTH_1 PF00126.27 EHT98177.1 - 7.2e-21 73.9 0.6 1.9e-20 72.6 0.6 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 EHT98177.1 - 2e-20 73.1 4.8 3.2e-20 72.4 4.8 1.2 1 0 0 1 1 1 1 LysR substrate binding domain ParD_like PF11903.8 EHT98178.1 - 5.1e-23 80.9 0.4 6e-23 80.7 0.4 1.1 1 0 0 1 1 1 1 ParD-like antitoxin of type II bacterial toxin-antitoxin system Peptidase_M24 PF00557.24 EHT98179.1 - 2e-50 171.4 1.0 2.3e-50 171.2 1.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3811 PF11656.8 EHT98180.1 - 0.22 11.9 5.9 0.48 10.8 5.9 1.7 1 1 0 1 1 1 0 YjbD family (DUF3811) TctB PF07331.11 EHT98181.1 - 0.0058 16.9 0.7 0.0058 16.9 0.7 2.4 1 1 1 2 2 2 1 Tripartite tricarboxylate transporter TctB family Bac_rhodopsin PF01036.18 EHT98181.1 - 0.015 14.9 8.8 0.22 11.1 8.3 2.1 1 1 0 1 1 1 0 Bacteriorhodopsin-like protein Amidinotransf PF02274.17 EHT98181.1 - 0.04 13.0 0.0 0.042 12.9 0.0 1.1 1 0 0 1 1 1 0 Amidinotransferase Hydrolase_3 PF08282.12 EHT98182.1 - 2.9e-51 174.7 0.0 3.3e-51 174.5 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EHT98182.1 - 1e-14 54.7 0.0 1.3e-10 41.3 0.0 2.3 2 1 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.7 EHT98182.1 - 2.5e-06 28.0 0.2 0.00055 20.4 0.0 3.1 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EHT98182.1 - 2.8e-06 27.8 0.1 0.0021 18.4 0.0 3.2 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EHT98182.1 - 0.012 15.7 0.2 0.34 11.0 0.0 2.6 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase DUF1479 PF07350.12 EHT98183.1 - 3.4e-131 437.8 0.1 4.2e-131 437.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) DeoRC PF00455.22 EHT98184.1 - 1.1e-38 132.8 0.0 1.5e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 EHT98184.1 - 2.3e-16 59.2 1.6 4.3e-16 58.4 1.6 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 EHT98184.1 - 1.9e-07 30.9 2.6 2.6e-07 30.5 0.9 2.0 2 0 0 2 2 2 1 HTH domain HTH_Mga PF08280.11 EHT98184.1 - 3e-05 23.9 0.8 0.00017 21.5 0.0 2.1 2 0 0 2 2 2 1 M protein trans-acting positive regulator (MGA) HTH domain HTH_AsnC-type PF13404.6 EHT98184.1 - 0.0018 18.0 1.6 0.011 15.5 1.6 2.2 1 1 0 1 1 1 1 AsnC-type helix-turn-helix domain GntR PF00392.21 EHT98184.1 - 0.0022 17.6 1.3 0.0045 16.6 1.3 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 EHT98184.1 - 0.0034 16.9 2.5 0.026 14.1 0.3 2.6 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding FaeA PF04703.12 EHT98184.1 - 0.0056 17.0 0.1 0.012 16.0 0.1 1.5 1 0 0 1 1 1 1 FaeA-like protein HTH_5 PF01022.20 EHT98184.1 - 0.01 15.7 1.6 0.011 15.6 0.1 1.8 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Rrf2 PF02082.20 EHT98184.1 - 0.015 15.7 1.0 0.024 15.0 0.1 1.8 2 0 0 2 2 1 0 Transcriptional regulator Sigma70_r4 PF04545.16 EHT98184.1 - 0.037 13.6 0.4 0.099 12.2 0.4 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 DUF977 PF06163.11 EHT98184.1 - 0.054 13.4 0.2 0.094 12.7 0.2 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) MarR PF01047.22 EHT98184.1 - 0.062 13.2 0.2 0.062 13.2 0.2 1.9 2 0 0 2 2 2 0 MarR family Put_DNA-bind_N PF06971.13 EHT98184.1 - 0.083 12.9 0.2 0.37 10.8 0.1 2.1 2 0 0 2 2 2 0 Putative DNA-binding protein N-terminus Exonuc_V_gamma PF04257.14 EHT98184.1 - 0.13 10.5 0.2 0.15 10.2 0.2 1.1 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit HTH_Crp_2 PF13545.6 EHT98184.1 - 0.13 12.3 2.1 0.15 12.0 0.5 1.9 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_20 PF12840.7 EHT98184.1 - 0.33 11.1 2.0 0.39 10.8 0.1 2.1 3 0 0 3 3 3 0 Helix-turn-helix domain Peripla_BP_3 PF13377.6 EHT98185.1 - 1.5e-33 116.5 0.0 7.1e-33 114.3 0.0 2.1 2 1 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 EHT98185.1 - 6e-21 75.1 0.0 8e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 EHT98185.1 - 5.4e-19 67.7 1.3 1.5e-18 66.3 0.2 2.3 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 EHT98185.1 - 4.6e-16 59.2 0.0 8.3e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein domain HTH_7 PF02796.15 EHT98185.1 - 0.0001 22.3 0.4 0.018 15.1 0.1 2.9 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_31 PF13560.6 EHT98185.1 - 0.00046 20.5 0.1 0.001 19.4 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 EHT98185.1 - 0.0005 20.1 0.1 0.00099 19.1 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix TetR_N PF00440.23 EHT98185.1 - 0.0023 17.7 0.2 0.0058 16.4 0.2 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_38 PF13936.6 EHT98185.1 - 0.0056 16.4 0.8 0.061 13.1 0.1 3.1 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_IclR PF09339.10 EHT98185.1 - 0.0063 16.3 0.2 0.019 14.8 0.1 1.9 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_23 PF13384.6 EHT98185.1 - 0.017 14.9 0.1 0.14 11.9 0.0 2.5 2 0 0 2 2 2 0 Homeodomain-like domain MarR_2 PF12802.7 EHT98185.1 - 0.031 14.1 0.2 0.12 12.2 0.1 2.1 2 0 0 2 2 2 0 MarR family MerR PF00376.23 EHT98185.1 - 0.068 13.0 0.3 0.16 11.8 0.3 1.6 1 0 0 1 1 1 0 MerR family regulatory protein HTH_Tnp_ISL3 PF13542.6 EHT98185.1 - 0.074 12.5 0.3 0.15 11.5 0.3 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 TrmB PF01978.19 EHT98185.1 - 0.074 12.9 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_6 PF01418.17 EHT98185.1 - 0.11 12.5 0.1 0.25 11.3 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family Fe_dep_repress PF01325.19 EHT98185.1 - 0.11 12.7 0.2 0.24 11.6 0.2 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_26 PF13443.6 EHT98185.1 - 0.17 12.3 0.0 0.39 11.2 0.0 1.7 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain PTS_EIIC PF02378.18 EHT98186.1 - 4.4e-40 137.7 30.8 8.1e-40 136.8 30.8 1.4 1 0 0 1 1 1 1 Phosphotransferase system, EIIC PTS_EIIB PF00367.20 EHT98186.1 - 1.7e-14 53.0 0.2 3.2e-14 52.1 0.2 1.5 1 0 0 1 1 1 1 phosphotransferase system, EIIB Glyco_hydro_1 PF00232.18 EHT98187.1 - 4.4e-132 440.7 0.0 5.2e-132 440.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.18 EHT98187.1 - 0.03 13.8 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) DeoRC PF00455.22 EHT98189.1 - 2.6e-48 164.0 0.1 3.4e-48 163.6 0.1 1.1 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 EHT98189.1 - 2.5e-14 52.7 0.1 4.8e-14 51.8 0.1 1.4 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain GntR PF00392.21 EHT98189.1 - 0.0025 17.4 0.0 0.0052 16.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_5 PF01022.20 EHT98189.1 - 0.0054 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family DprA_WH PF17782.1 EHT98189.1 - 0.0056 16.8 0.3 0.023 14.8 0.0 2.1 3 0 0 3 3 3 1 DprA winged helix domain HTH_Crp_2 PF13545.6 EHT98189.1 - 0.025 14.5 0.1 0.074 13.0 0.0 1.8 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain DUF1338 PF07063.13 EHT98189.1 - 0.063 12.4 0.0 0.093 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1338) HTH_11 PF08279.12 EHT98189.1 - 0.074 13.0 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 HTH domain HTH_29 PF13551.6 EHT98189.1 - 0.077 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix DUF853 PF05872.12 EHT98189.1 - 0.082 11.5 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) UBA_4 PF14555.6 EHT98189.1 - 0.11 12.3 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 UBA-like domain Rrf2 PF02082.20 EHT98189.1 - 0.12 12.7 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator EAL PF00563.20 EHT98190.1 - 6.2e-36 124.1 0.1 1.4e-35 122.9 0.1 1.5 1 1 0 1 1 1 1 EAL domain BLUF PF04940.12 EHT98191.1 - 4.2e-20 71.7 0.0 6.3e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 Sensors of blue-light using FAD GAF_2 PF13185.6 EHT98192.1 - 1.8e-11 44.5 0.0 4.3e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 EHT98192.1 - 7.1e-11 42.9 0.1 1.7e-10 41.6 0.1 1.6 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 EHT98192.1 - 1.6e-08 34.9 0.0 3.5e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 GAF domain GGDEF PF00990.21 EHT98192.1 - 0.0018 18.1 0.1 0.0026 17.5 0.1 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain EAL PF00563.20 EHT98193.1 - 3.3e-36 125.0 0.0 3.9e-36 124.8 0.0 1.0 1 0 0 1 1 1 1 EAL domain GrpB PF04229.14 EHT98195.1 - 7.8e-41 139.9 0.1 8.5e-41 139.8 0.1 1.0 1 0 0 1 1 1 1 GrpB protein PseudoU_synth_2 PF00849.22 EHT98196.1 - 1.6e-15 57.6 0.1 2.2e-14 53.9 0.1 2.2 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 EHT98196.1 - 8e-10 38.3 1.8 2e-09 37.0 0.1 2.5 2 1 1 3 3 3 1 S4 domain S4_2 PF13275.6 EHT98196.1 - 0.0027 17.5 0.9 0.0057 16.5 0.1 2.0 2 0 0 2 2 2 1 S4 domain Autotransporter PF03797.19 EHT98197.1 - 3.3e-39 135.1 16.9 4.4e-39 134.7 16.9 1.1 1 0 0 1 1 1 1 Autotransporter beta-domain OMP_b-brl PF13505.6 EHT98197.1 - 0.001 19.3 8.7 0.021 14.9 2.5 2.8 1 1 2 3 3 3 3 Outer membrane protein beta-barrel domain DDE_Tnp_IS1 PF03400.13 EHT98198.1 - 6.1e-36 123.6 0.7 6.6e-36 123.5 0.7 1.0 1 0 0 1 1 1 1 IS1 transposase HTH_Tnp_IS1 PF12759.7 EHT98199.1 - 2.6e-18 65.3 1.0 2.8e-18 65.2 1.0 1.0 1 0 0 1 1 1 1 InsA C-terminal domain HTH_Tnp_ISL3 PF13542.6 EHT98199.1 - 0.035 13.5 0.0 0.035 13.5 0.0 1.0 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 EHT98199.1 - 0.11 12.3 0.0 0.11 12.3 0.0 1.0 1 0 0 1 1 1 0 Homeodomain-like domain TnpB_IS66 PF05717.13 EHT98201.1 - 4.6e-21 74.6 0.0 5.1e-21 74.5 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DUF1275 PF06912.11 EHT98203.1 - 1.1e-28 100.5 17.4 1.4e-28 100.1 17.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Ycf66_N PF07444.11 EHT98203.1 - 0.22 11.7 4.3 49 4.1 0.0 3.4 3 0 0 3 3 3 0 Ycf66 protein N-terminus GPI2 PF06432.11 EHT98203.1 - 1.8 7.9 5.7 0.54 9.7 1.0 2.1 1 1 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase Ribonuc_L-PSP PF01042.21 EHT98205.1 - 1.8e-20 73.2 0.2 2.1e-20 72.9 0.2 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF835 PF05763.12 EHT98206.1 - 0.16 11.7 0.0 0.18 11.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF835) ParB PF08775.10 EHT98208.1 - 5.1e-46 156.2 2.2 9.5e-46 155.4 2.2 1.5 1 0 0 1 1 1 1 ParB family ParBc PF02195.18 EHT98208.1 - 2.3e-06 27.8 0.3 7.2e-06 26.2 0.1 1.9 2 0 0 2 2 2 1 ParB-like nuclease domain HTH_24 PF13412.6 EHT98208.1 - 0.00018 21.0 1.7 0.00036 20.0 0.1 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_31 PF13560.6 EHT98208.1 - 0.0012 19.2 0.8 0.0031 17.8 0.8 1.7 1 1 0 1 1 1 1 Helix-turn-helix domain Trp_repressor PF01371.19 EHT98208.1 - 0.0012 18.9 0.1 0.0038 17.3 0.1 1.8 1 0 0 1 1 1 1 Trp repressor protein SoPB_HTH PF18090.1 EHT98208.1 - 0.0073 16.4 0.0 0.021 14.9 0.0 1.8 1 0 0 1 1 1 1 Centromere-binding protein HTH domain Sigma70_r4_2 PF08281.12 EHT98208.1 - 0.0082 15.8 0.1 0.023 14.4 0.1 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 EHT98208.1 - 0.017 14.9 0.3 0.061 13.1 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_IclR PF09339.10 EHT98208.1 - 0.023 14.5 0.1 0.059 13.2 0.1 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain MarR_2 PF12802.7 EHT98208.1 - 0.032 14.1 0.1 0.081 12.8 0.1 1.7 1 0 0 1 1 1 0 MarR family HTH_29 PF13551.6 EHT98208.1 - 0.052 13.6 0.0 0.21 11.6 0.0 2.0 1 0 0 1 1 1 0 Winged helix-turn helix HTH_28 PF13518.6 EHT98208.1 - 0.099 12.8 0.4 0.4 10.8 0.0 2.2 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_54 PF18607.1 EHT98209.1 - 5.6e-43 144.9 1.6 9.6e-43 144.2 1.6 1.4 1 0 0 1 1 1 1 ParA helix turn helix domain AAA_31 PF13614.6 EHT98209.1 - 8.2e-26 91.0 0.0 1.6e-25 90.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 EHT98209.1 - 5.8e-07 29.6 0.0 1e-06 28.8 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 EHT98209.1 - 2.6e-06 26.9 0.9 0.0039 16.5 0.1 2.7 3 0 0 3 3 3 2 ATPase MipZ CBP_BcsQ PF06564.12 EHT98209.1 - 0.00011 21.8 0.1 0.00061 19.3 0.1 2.0 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Methyltransf_24 PF13578.6 EHT98209.1 - 0.0083 17.1 0.1 0.051 14.6 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain VirC1 PF07015.11 EHT98209.1 - 0.04 13.2 0.1 0.43 9.8 0.0 2.2 2 0 0 2 2 2 0 VirC1 protein ParA PF10609.9 EHT98209.1 - 0.15 11.5 0.0 0.42 10.0 0.0 1.8 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase ArsA_ATPase PF02374.15 EHT98209.1 - 0.25 10.5 1.3 0.6 9.2 0.0 2.2 2 1 0 2 2 2 0 Anion-transporting ATPase Rep_3 PF01051.21 EHT98211.1 - 7.3e-25 88.1 0.0 9.1e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 Initiator Replication protein Aldedh PF00171.22 EHT98212.1 - 1.5e-133 445.7 0.3 1.8e-133 445.4 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family baeRF_family2 PF18844.1 EHT98212.1 - 0.044 13.8 3.5 0.06 13.4 1.0 2.3 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 2 Nucleopor_Nup85 PF07575.13 EHT98212.1 - 0.16 10.5 0.0 0.23 10.0 0.0 1.1 1 0 0 1 1 1 0 Nup85 Nucleoporin cobW PF02492.19 EHT98213.1 - 6.8e-60 201.7 0.1 8.5e-60 201.3 0.1 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EHT98213.1 - 5.4e-28 96.8 0.3 1.6e-27 95.2 0.1 1.9 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 EHT98213.1 - 0.00049 20.0 0.1 0.097 12.6 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase MeaB PF03308.16 EHT98213.1 - 0.0019 17.3 0.0 0.69 8.8 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB T2SSE PF00437.20 EHT98213.1 - 0.012 14.7 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 EHT98213.1 - 0.018 15.4 0.1 0.05 14.0 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 EHT98213.1 - 0.026 14.5 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TsaE PF02367.17 EHT98213.1 - 0.042 13.9 0.0 0.08 12.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 EHT98213.1 - 0.067 12.9 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 EHT98213.1 - 0.12 11.6 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin MobB PF03205.14 EHT98213.1 - 0.13 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.27 EHT98213.1 - 0.15 11.5 0.0 13 5.2 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EHT98213.1 - 0.2 11.8 0.1 0.46 10.6 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase SBP_bac_5 PF00496.22 EHT98214.1 - 3.5e-74 250.0 0.0 4.6e-74 249.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle BPD_transp_1 PF00528.22 EHT98215.1 - 1.2e-30 106.6 5.2 1.2e-30 106.6 5.2 1.9 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 EHT98216.1 - 4.7e-14 52.5 20.0 4.7e-14 52.5 20.0 1.7 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 EHT98216.1 - 0.03 14.3 1.1 0.03 14.3 1.1 3.7 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C ABC_tran PF00005.27 EHT98217.1 - 3.1e-43 147.6 0.0 1.7e-20 73.9 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EHT98217.1 - 1.2e-10 41.7 4.6 0.051 13.4 0.2 4.1 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EHT98217.1 - 1.2e-09 38.7 0.8 0.00034 21.0 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EHT98217.1 - 1.2e-06 28.2 0.3 0.0033 17.1 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 EHT98217.1 - 4.4e-05 23.0 0.5 1.3 8.4 0.0 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EHT98217.1 - 0.00023 21.7 0.3 0.56 10.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EHT98217.1 - 0.0004 20.7 0.4 0.63 10.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EHT98217.1 - 0.00093 18.8 0.0 0.075 12.5 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 EHT98217.1 - 0.0011 18.7 0.0 0.086 12.5 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.12 EHT98217.1 - 0.003 17.5 0.1 0.52 10.2 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Mg_chelatase PF01078.21 EHT98217.1 - 0.0049 16.3 0.1 0.32 10.3 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EHT98217.1 - 0.0059 17.0 0.2 5 7.6 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_5 PF07728.14 EHT98217.1 - 0.0076 16.2 0.2 5 7.1 0.1 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 EHT98217.1 - 0.013 15.4 0.2 0.7 9.8 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase oligo_HPY PF08352.12 EHT98217.1 - 0.053 14.1 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Oligopeptide/dipeptide transporter, C-terminal region MMR_HSR1 PF01926.23 EHT98217.1 - 0.054 13.6 0.1 9.7 6.3 0.1 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.17 EHT98217.1 - 0.064 13.3 0.6 1.5 8.8 0.0 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_25 PF13481.6 EHT98217.1 - 0.071 12.7 0.8 15 5.0 0.0 3.3 3 1 0 3 3 3 0 AAA domain TsaE PF02367.17 EHT98217.1 - 0.086 12.8 0.2 8.7 6.4 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 EHT98217.1 - 0.11 11.9 0.2 8.8 5.6 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.6 EHT98217.1 - 0.12 12.1 0.9 2.6 7.7 0.3 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EHT98217.1 - 0.37 10.9 3.1 1.2 9.3 0.1 2.8 3 1 0 3 3 2 0 AAA domain HTH_3 PF01381.22 EHT98218.1 - 2.4e-13 49.9 0.0 3.4e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EHT98218.1 - 1.1e-10 41.7 0.4 2e-10 40.8 0.4 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 EHT98218.1 - 1.2e-07 31.6 0.0 1.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Cupin_2 PF07883.11 EHT98218.1 - 1.9e-06 27.4 0.0 2.9e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Cupin domain HTH_26 PF13443.6 EHT98218.1 - 3.3e-06 27.4 0.0 5.6e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 EHT98218.1 - 2e-05 24.4 0.2 4.4e-05 23.2 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 EHT98218.1 - 0.00056 19.7 0.3 0.0012 18.6 0.3 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_37 PF13744.6 EHT98218.1 - 0.0033 17.4 0.1 0.0084 16.1 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain Cupin_6 PF12852.7 EHT98218.1 - 0.0036 17.0 0.1 0.0076 16.0 0.0 1.5 2 0 0 2 2 2 1 Cupin Sigma70_r4 PF04545.16 EHT98218.1 - 0.006 16.1 0.2 0.012 15.1 0.2 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 TetR_N PF00440.23 EHT98218.1 - 0.021 14.6 0.2 0.035 13.9 0.2 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family HTH_Tnp_1 PF01527.20 EHT98218.1 - 0.03 14.6 0.1 0.059 13.7 0.1 1.4 1 0 0 1 1 1 0 Transposase LacI PF00356.21 EHT98218.1 - 0.047 13.5 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family HTH_20 PF12840.7 EHT98218.1 - 0.095 12.8 0.1 0.36 10.9 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.7 EHT98218.1 - 0.1 12.5 0.7 0.2 11.6 0.2 1.7 2 0 0 2 2 1 0 MarR family HTH_35 PF13693.6 EHT98218.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_38 PF13936.6 EHT98218.1 - 0.11 12.3 1.0 0.19 11.5 0.2 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain Cupin_3 PF05899.12 EHT98218.1 - 0.14 11.9 0.0 0.27 10.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF861) HTH_23 PF13384.6 EHT98218.1 - 0.21 11.4 1.1 0.39 10.6 0.1 1.8 2 0 0 2 2 2 0 Homeodomain-like domain AzlC PF03591.14 EHT98219.1 - 9.8e-29 100.5 5.6 1.7e-28 99.7 5.6 1.3 1 0 0 1 1 1 1 AzlC protein GerA PF03323.13 EHT98219.1 - 0.029 12.8 0.5 0.041 12.4 0.5 1.2 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein TMEM65 PF10507.9 EHT98219.1 - 0.068 13.1 3.0 0.087 12.8 0.2 2.3 1 1 1 2 2 2 0 Transmembrane protein 65 AzlD PF05437.12 EHT98220.1 - 1.3e-12 47.7 9.3 1.7e-12 47.4 9.3 1.2 1 0 0 1 1 1 1 Branched-chain amino acid transport protein (AzlD) DAO PF01266.24 EHT98221.1 - 6.1e-37 128.0 3.3 1.8e-35 123.2 3.3 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EHT98221.1 - 0.00029 20.0 1.9 0.00032 19.9 1.9 1.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EHT98221.1 - 0.00055 20.1 0.1 0.0018 18.5 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EHT98221.1 - 0.03 13.6 0.1 0.053 12.8 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 EHT98221.1 - 0.06 13.9 0.0 0.16 12.5 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EHT98221.1 - 0.14 11.8 0.1 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiS PF02597.20 EHT98222.1 - 7.6e-09 36.1 0.0 9.4e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 ThiS family DUF348 PF03990.14 EHT98222.1 - 0.0032 17.2 0.0 0.0047 16.6 0.0 1.4 1 0 0 1 1 1 1 G5-linked-Ubiquitin-like domain ThiS-like PF14453.6 EHT98222.1 - 0.031 14.3 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 ThiS-like ubiquitin ThiG PF05690.14 EHT98223.1 - 1.1e-100 336.1 0.0 1.2e-100 335.9 0.0 1.0 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 EHT98223.1 - 0.00049 19.6 0.0 0.0099 15.4 0.0 2.1 2 0 0 2 2 2 1 Histidine biosynthesis protein Glyco_trans_4_5 PF16994.5 EHT98223.1 - 0.059 13.0 0.0 0.23 11.1 0.0 1.9 1 1 0 1 1 1 0 Glycosyl-transferase family 4 NanE PF04131.14 EHT98223.1 - 0.079 12.1 0.0 0.29 10.3 0.0 1.9 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase ThiF PF00899.21 EHT98224.1 - 3.7e-48 164.0 0.0 5.1e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 EHT98224.1 - 0.0056 16.7 0.0 0.86 9.7 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EHT98224.1 - 0.011 16.2 0.1 0.032 14.7 0.0 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Rhodanese PF00581.20 EHT98224.1 - 0.046 14.2 0.0 0.085 13.4 0.0 1.4 1 0 0 1 1 1 0 Rhodanese-like domain Sacchrp_dh_NADP PF03435.18 EHT98224.1 - 0.12 12.6 2.3 1.6 9.0 0.9 2.5 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Acetyltransf_7 PF13508.7 EHT98225.1 - 1.3e-08 35.1 0.0 1.7e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EHT98225.1 - 3.6e-06 26.9 0.0 4.7e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EHT98225.1 - 1.2e-05 25.5 0.1 1.7e-05 25.1 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EHT98225.1 - 0.02 14.8 0.0 0.044 13.8 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein LysE PF01810.18 EHT98226.1 - 3.6e-25 88.6 18.6 4e-25 88.4 18.6 1.0 1 0 0 1 1 1 1 LysE type translocator Mntp PF02659.15 EHT98226.1 - 0.0061 16.3 12.4 0.11 12.2 12.4 2.2 1 1 0 1 1 1 1 Putative manganese efflux pump Glyoxalase PF00903.25 EHT98227.1 - 5.1e-05 23.5 0.0 9.8e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EHT98227.1 - 0.029 15.2 0.0 0.16 12.8 0.0 1.9 1 1 0 1 1 1 0 Glyoxalase-like domain ASCH PF04266.14 EHT98228.1 - 2.2e-20 73.2 0.0 2.6e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 ASCH domain Thioredoxin_4 PF13462.6 EHT98229.1 - 0.0016 18.6 0.0 0.0026 18.0 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin Flavin_Reduct PF01613.18 EHT98230.1 - 5.4e-14 52.5 0.0 7e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain ADH_N PF08240.12 EHT98231.1 - 1.2e-25 89.5 2.9 2.2e-25 88.7 2.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EHT98231.1 - 1.2e-21 77.1 0.0 2e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EHT98231.1 - 2.4e-10 41.6 0.0 3.9e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EHT98231.1 - 5.8e-09 35.6 0.1 9.1e-09 34.9 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EHT98231.1 - 3.6e-05 23.2 0.1 5.6e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EHT98231.1 - 0.0037 17.4 0.1 0.014 15.6 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EHT98231.1 - 0.0054 16.8 0.2 0.0094 16.0 0.2 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Oxidored_nitro PF00148.19 EHT98231.1 - 0.0063 15.3 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase ThiF PF00899.21 EHT98231.1 - 0.018 14.4 0.3 0.033 13.6 0.3 1.4 1 0 0 1 1 1 0 ThiF family Sacchrp_dh_NADP PF03435.18 EHT98231.1 - 0.023 14.9 0.2 0.039 14.2 0.2 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 EHT98231.1 - 0.19 12.4 1.2 7.3 7.2 1.0 2.3 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent FA_hydroxylase PF04116.13 EHT98232.1 - 1.2e-08 35.4 7.8 1.5e-08 35.1 7.8 1.1 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily SQS_PSY PF00494.19 EHT98233.1 - 8.3e-66 222.2 6.9 1e-65 221.9 6.9 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase Amino_oxidase PF01593.24 EHT98234.1 - 6.9e-42 144.3 0.0 8.7e-42 143.9 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EHT98234.1 - 2.9e-14 53.0 0.1 8.3e-14 51.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EHT98234.1 - 6.6e-08 32.5 4.2 9.5e-07 28.7 1.9 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EHT98234.1 - 7.4e-05 22.1 0.0 0.00066 19.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EHT98234.1 - 0.00011 22.7 0.2 0.19 12.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EHT98234.1 - 0.00021 20.5 0.2 0.00059 19.0 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 EHT98234.1 - 0.0019 17.6 0.4 0.11 11.8 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EHT98234.1 - 0.007 15.1 0.0 0.051 12.3 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 EHT98234.1 - 0.0084 15.4 0.1 0.014 14.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EHT98234.1 - 0.0086 15.4 0.1 0.014 14.7 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EHT98234.1 - 0.011 14.8 0.2 0.047 12.7 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 EHT98234.1 - 0.092 12.7 1.6 0.37 10.8 0.5 2.5 2 1 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 EHT98234.1 - 0.1 11.7 0.1 0.19 10.8 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EHT98235.1 - 6.5e-93 311.8 0.0 7.5e-93 311.6 0.0 1.0 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EHT98235.1 - 0.00098 19.3 0.0 0.0024 18.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EHT98235.1 - 0.069 12.4 0.0 0.17 11.1 0.0 1.6 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.24 EHT98235.1 - 0.073 12.1 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain UDPGT PF00201.18 EHT98236.1 - 7.4e-11 41.5 0.0 3.1e-09 36.2 0.0 2.5 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 EHT98236.1 - 1e-07 32.1 0.0 1.7e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_4_4 PF13579.6 EHT98236.1 - 0.00042 20.8 3.8 0.00042 20.8 3.8 2.4 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 EHT98236.1 - 0.00061 19.8 0.1 0.0024 17.9 0.1 2.1 1 1 0 1 1 1 1 Glycosyltransferase Family 4 polyprenyl_synt PF00348.17 EHT98237.1 - 8.5e-43 146.3 0.2 1.1e-42 145.9 0.2 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase YtfJ_HI0045 PF09695.10 EHT98238.1 - 9e-56 187.9 0.0 1e-55 187.8 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (YtfJ_HI0045) HTH_17 PF12728.7 EHT98239.1 - 0.00035 20.7 0.0 0.00068 19.8 0.0 1.5 2 0 0 2 2 2 1 Helix-turn-helix domain ANT PF03374.14 EHT98239.1 - 0.08 13.3 0.0 0.13 12.6 0.0 1.5 1 1 0 1 1 1 0 Phage antirepressor protein KilAC domain PepSY_TM PF03929.16 EHT98240.1 - 3.2e-65 220.7 10.2 3.2e-65 220.7 10.2 1.7 2 1 0 2 2 2 1 PepSY-associated TM region DUF2534 PF10749.9 EHT98240.1 - 9.2e-33 112.3 5.3 2.7e-32 110.8 5.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2534) PepSY PF03413.19 EHT98240.1 - 0.01 16.4 0.0 0.033 14.7 0.0 1.8 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain DUF2946 PF11162.8 EHT98241.1 - 2.4e-15 57.2 8.1 2.8e-15 57.0 8.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2946) 2-Hacid_dh_C PF02826.19 EHT98242.1 - 1.1e-55 187.7 0.0 1.6e-55 187.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EHT98242.1 - 3.6e-22 78.5 0.0 4.5e-22 78.1 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.6 EHT98242.1 - 0.05 14.1 0.0 0.087 13.3 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain Pyr_redox PF00070.27 EHT98242.1 - 0.13 12.8 0.1 0.23 12.1 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glutaminase PF04960.15 EHT98243.1 - 1.3e-112 375.7 0.0 1.5e-112 375.5 0.0 1.0 1 0 0 1 1 1 1 Glutaminase Voltage_CLC PF00654.20 EHT98244.1 - 1.6e-92 310.5 35.1 3e-91 306.3 28.2 2.0 1 1 1 2 2 2 2 Voltage gated chloride channel Toxin_GhoT_OrtT PF10753.9 EHT98245.1 - 2.6e-24 85.2 6.8 2.9e-24 85.1 6.8 1.0 1 0 0 1 1 1 1 Toxin GhoT_OrtT DUF3938 PF13074.6 EHT98245.1 - 0.11 12.7 1.9 0.13 12.5 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3938) PBP PF01161.20 EHT98246.1 - 4.2e-30 104.8 0.0 5.2e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Sugar_tr PF00083.24 EHT98247.1 - 8e-48 163.4 32.2 1.6e-34 119.6 9.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EHT98247.1 - 4e-45 154.3 66.8 9.1e-38 130.1 39.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Hol_Tox PF16935.5 EHT98247.1 - 0.087 12.9 3.7 1.2 9.3 0.1 2.8 2 0 0 2 2 2 0 Putative Holin-like Toxin (Hol-Tox) MFS_1 PF07690.16 EHT98248.1 - 5.4e-32 111.1 43.5 1.5e-26 93.2 21.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EHT98248.1 - 1.2e-12 47.4 15.1 3.6e-12 45.8 15.1 1.8 1 1 0 1 1 1 1 MFS_1 like family Trp_oprn_chp PF09534.10 EHT98248.1 - 0.0084 15.9 6.5 0.0084 15.9 6.5 3.5 3 2 0 3 3 3 2 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Folate_carrier PF01770.18 EHT98248.1 - 0.02 13.7 1.7 0.032 13.0 0.2 2.1 2 0 0 2 2 2 0 Reduced folate carrier MFS_3 PF05977.13 EHT98248.1 - 0.053 11.9 28.6 0.0049 15.3 10.0 2.3 1 1 1 2 2 2 0 Transmembrane secretion effector LacY_symp PF01306.19 EHT98248.1 - 1.5 7.5 17.1 9 4.9 17.1 1.9 1 1 0 1 1 1 0 LacY proton/sugar symporter CDH PF02611.15 EHT98249.1 - 7.1e-67 225.3 0.0 8.1e-67 225.1 0.0 1.0 1 0 0 1 1 1 1 CDP-diacylglycerol pyrophosphatase LPAM_1 PF08139.12 EHT98249.1 - 9.5 6.9 7.4 1.9 9.1 2.4 2.2 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site LysR_substrate PF03466.20 EHT98250.1 - 1.3e-39 135.8 3.5 1.8e-39 135.3 3.5 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EHT98250.1 - 6.5e-20 70.8 1.2 6.5e-20 70.8 1.2 1.9 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 EHT98250.1 - 0.011 15.6 0.2 0.033 14.1 0.2 1.7 1 0 0 1 1 1 0 MarR family Epimerase PF01370.21 EHT98251.1 - 2.5e-12 46.8 0.0 3.2e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EHT98251.1 - 1.2e-06 28.5 0.0 2.7e-06 27.4 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EHT98251.1 - 1.7e-05 24.0 0.0 3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 EHT98251.1 - 0.0022 17.5 0.0 0.004 16.7 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 EHT98251.1 - 0.0023 17.4 0.1 0.0076 15.7 0.1 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EHT98252.1 - 9.8e-39 133.1 1.9 1.2e-38 132.9 1.9 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EHT98252.1 - 2.2e-10 40.5 1.3 2.8e-10 40.2 0.8 1.4 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 EHT98252.1 - 1.1e-05 25.0 0.1 1.5e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EHT98252.1 - 0.00036 19.6 0.0 0.00046 19.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 EHT98252.1 - 0.0073 16.7 0.4 0.013 15.9 0.4 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EHT98252.1 - 0.02 15.4 0.8 0.1 13.2 0.1 2.4 2 1 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.17 EHT98252.1 - 0.034 13.2 0.2 0.06 12.4 0.1 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain TrkA_N PF02254.18 EHT98252.1 - 0.037 14.3 0.3 0.095 13.0 0.0 1.8 2 1 0 2 2 2 0 TrkA-N domain DapB_N PF01113.20 EHT98252.1 - 0.094 12.8 0.5 0.26 11.4 0.2 1.8 1 1 1 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Fumerase_C PF05683.12 EHT98253.1 - 4.3e-88 294.0 0.0 7.1e-88 293.3 0.0 1.4 1 0 0 1 1 1 1 Fumarase C-terminus Fumerase PF05681.14 EHT98253.1 - 7.1e-86 288.0 0.0 9.2e-86 287.6 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Myosin_head PF00063.21 EHT98253.1 - 0.048 11.9 0.0 0.069 11.4 0.0 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) Na_sulph_symp PF00939.19 EHT98254.1 - 3e-149 498.1 41.3 3.6e-149 497.8 41.3 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 EHT98254.1 - 1.1e-11 44.4 54.5 6.7e-09 35.4 29.0 2.9 1 1 1 2 2 2 2 Citrate transporter FAD_binding_2 PF00890.24 EHT98255.1 - 8.9e-85 285.3 5.6 1.2e-84 284.8 5.6 1.2 1 0 0 1 1 1 1 FAD binding domain Oxidored_FMN PF00724.20 EHT98255.1 - 4.4e-76 256.4 0.0 8.1e-76 255.5 0.0 1.4 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FAD_oxidored PF12831.7 EHT98255.1 - 3e-13 49.9 2.8 1.1e-12 48.0 2.8 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EHT98255.1 - 1.9e-11 43.7 0.4 5.5e-11 42.2 0.4 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EHT98255.1 - 2e-10 40.8 0.4 2.6e-06 27.3 0.0 2.6 1 1 1 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EHT98255.1 - 3.5e-10 39.1 3.9 3.5e-10 39.1 3.9 2.4 2 1 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 EHT98255.1 - 4.1e-09 36.0 3.4 4.1e-09 36.0 3.4 2.4 2 1 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EHT98255.1 - 6.2e-07 29.6 0.1 1.7e-06 28.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMN_bind PF04205.14 EHT98255.1 - 1.2e-06 29.0 2.5 3.3e-06 27.6 0.4 2.8 3 0 0 3 3 2 1 FMN-binding domain Pyr_redox_3 PF13738.6 EHT98255.1 - 7.8e-06 25.3 1.6 0.0051 16.1 0.4 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EHT98255.1 - 1.4e-05 24.4 6.5 0.00018 20.8 0.4 3.3 3 0 0 3 3 3 1 Thi4 family Pyr_redox PF00070.27 EHT98255.1 - 9.1e-05 22.9 3.4 0.0049 17.4 0.7 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EHT98255.1 - 0.00029 20.2 0.1 0.00051 19.4 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain GMC_oxred_N PF00732.19 EHT98255.1 - 0.0011 18.4 0.2 0.0085 15.5 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase DHO_dh PF01180.21 EHT98255.1 - 0.0017 17.6 0.0 0.0063 15.8 0.0 1.9 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase His_biosynth PF00977.21 EHT98255.1 - 0.0055 16.2 0.0 0.017 14.6 0.0 1.9 1 0 0 1 1 1 1 Histidine biosynthesis protein AlaDh_PNT_C PF01262.21 EHT98255.1 - 0.0077 15.6 0.7 0.0077 15.6 0.7 2.5 3 0 0 3 3 2 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 EHT98255.1 - 0.01 14.9 0.9 0.051 12.6 0.4 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein Amino_oxidase PF01593.24 EHT98255.1 - 0.013 14.8 0.4 1.8 7.8 0.1 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Candida_ALS PF05792.13 EHT98255.1 - 0.061 13.9 0.3 0.22 12.1 0.3 2.1 1 0 0 1 1 1 0 Candida agglutinin-like (ALS) NAD_binding_7 PF13241.6 EHT98255.1 - 0.13 12.7 0.5 0.75 10.3 0.0 2.5 3 0 0 3 3 2 0 Putative NAD(P)-binding ApbE PF02424.15 EHT98256.1 - 7e-75 251.9 0.0 8.8e-75 251.6 0.0 1.0 1 0 0 1 1 1 1 ApbE family Response_reg PF00072.24 EHT98257.1 - 6.9e-20 71.3 0.0 9.6e-20 70.8 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain CitT PF12431.8 EHT98257.1 - 0.0044 17.3 0.0 0.01 16.1 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator Rrf2 PF02082.20 EHT98257.1 - 0.046 14.1 0.0 0.085 13.2 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator CReP_N PF10472.9 EHT98257.1 - 0.12 11.3 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 eIF2-alpha phosphatase phosphorylation constitutive repressor sCache_3_2 PF17203.4 EHT98258.1 - 2.4e-23 82.8 1.0 1.2e-21 77.3 0.8 2.3 2 0 0 2 2 2 1 Single cache domain 3 HATPase_c PF02518.26 EHT98258.1 - 7.2e-17 61.9 0.0 1.5e-16 60.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPOB_a PF14689.6 EHT98258.1 - 8.7e-12 44.6 2.4 2.2e-11 43.3 2.4 1.7 1 0 0 1 1 1 1 Sensor_kinase_SpoOB-type, alpha-helical domain HATPase_c_5 PF14501.6 EHT98258.1 - 2.2e-10 40.4 0.0 9.8e-08 31.8 0.0 2.4 2 0 0 2 2 2 2 GHKL domain PAS PF00989.25 EHT98258.1 - 4.1e-06 26.8 0.0 1.3e-05 25.1 0.0 1.9 1 1 0 1 1 1 1 PAS fold sCache_3_3 PF17202.4 EHT98258.1 - 0.00012 22.5 0.0 0.65 10.5 0.0 2.5 2 0 0 2 2 2 2 Single cache domain 3 HATPase_c_2 PF13581.6 EHT98258.1 - 0.00022 21.2 0.0 0.00054 19.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PAS_4 PF08448.10 EHT98258.1 - 0.00027 21.2 0.1 0.0015 18.8 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 EHT98258.1 - 0.00044 20.2 0.0 0.0013 18.7 0.0 1.8 1 0 0 1 1 1 1 PAS domain dCache_3 PF14827.6 EHT98258.1 - 0.0067 16.1 1.3 0.015 14.9 0.2 2.1 2 1 0 2 2 2 1 Double sensory domain of two-component sensor kinase HATPase_c_3 PF13589.6 EHT98258.1 - 0.012 15.5 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_7 PF12860.7 EHT98258.1 - 0.053 13.7 0.1 0.62 10.2 0.0 2.3 1 1 1 2 2 2 0 PAS fold PAS_10 PF13596.6 EHT98258.1 - 0.076 13.6 0.0 0.32 11.6 0.0 2.1 1 1 0 1 1 1 0 PAS domain DUF2530 PF10745.9 EHT98258.1 - 0.16 12.2 1.1 0.46 10.7 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) Transposase_31 PF04754.12 EHT98259.1 - 4.7e-84 281.1 0.0 6.6e-84 280.6 0.0 1.2 1 0 0 1 1 1 1 Putative transposase, YhgA-like LPD23 PF18838.1 EHT98259.1 - 0.015 15.1 1.0 0.065 13.0 0.2 2.2 2 0 0 2 2 2 0 Large polyvalent protein associated domain 23 Yae1_N PF09811.9 EHT98259.1 - 0.58 9.9 3.6 1.2 9.0 3.6 1.4 1 0 0 1 1 1 0 Essential protein Yae1, N terminal Mqo PF06039.15 EHT98260.1 - 2.6e-232 771.6 0.1 3e-232 771.4 0.1 1.0 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) FAD_binding_3 PF01494.19 EHT98260.1 - 2.5e-05 23.7 0.1 0.00023 20.5 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain K_oxygenase PF13434.6 EHT98260.1 - 0.011 14.8 0.0 0.079 12.1 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) VF530 PF09905.9 EHT98261.1 - 2e-32 111.1 0.0 2.6e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 DNA-binding protein VF530 Pyridoxal_deC PF00282.19 EHT98262.1 - 5.5e-64 216.2 0.3 7e-64 215.9 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 EHT98262.1 - 6.3e-08 32.2 1.1 1.4e-07 31.1 1.1 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EHT98262.1 - 0.00011 21.3 1.5 0.00053 19.0 0.5 2.4 2 1 0 2 2 2 1 Aminotransferase class-V OKR_DC_1 PF01276.20 EHT98262.1 - 0.0088 14.8 0.1 0.017 13.8 0.1 1.6 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_1_2 PF00155.21 EHT98262.1 - 0.011 14.9 0.4 0.037 13.2 0.0 2.0 2 1 0 2 2 2 0 Aminotransferase class I and II SepSecS PF05889.13 EHT98262.1 - 0.026 13.3 0.0 0.053 12.2 0.0 1.5 2 0 0 2 2 2 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Aminotran_3 PF00202.21 EHT98263.1 - 3.2e-101 338.9 0.0 3.9e-101 338.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EHT98263.1 - 0.002 17.4 0.0 0.012 14.8 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class I and II TetR_C_6 PF13977.6 EHT98264.1 - 4.1e-12 46.3 0.2 1.9e-11 44.2 0.1 1.9 2 0 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal TetR_N PF00440.23 EHT98264.1 - 5.5e-11 42.1 0.9 1.2e-10 41.0 0.1 2.0 2 1 1 3 3 3 1 Bacterial regulatory proteins, tetR family TetR_C_27 PF17935.1 EHT98264.1 - 1.4e-05 25.1 0.0 2.4e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_7 PF14246.6 EHT98264.1 - 0.00058 19.9 0.0 0.003 17.6 0.0 2.1 2 0 0 2 2 2 1 AefR-like transcriptional repressor, C-terminal domain TetR_C_24 PF17932.1 EHT98264.1 - 0.0025 18.0 0.0 0.0081 16.4 0.0 1.9 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_5 PF08360.11 EHT98264.1 - 0.013 15.7 0.0 0.02 15.1 0.0 1.3 1 0 0 1 1 1 0 QacR-like protein, C-terminal region HTH_23 PF13384.6 EHT98264.1 - 0.013 15.2 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Phage_CII PF05269.11 EHT98264.1 - 0.052 13.8 0.0 3.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Bacteriophage CII protein Phage_AlpA PF05930.12 EHT98264.1 - 0.054 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) HTH_Tnp_1_2 PF13022.6 EHT98264.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase FAD-SLDH PF12318.8 EHT98265.1 - 3.6e-41 140.9 0.6 4e-41 140.8 0.6 1.0 1 0 0 1 1 1 1 Membrane bound FAD containing D-sorbitol dehydrogenase Cytochrome_CBB3 PF13442.6 EHT98266.1 - 4.4e-17 62.2 0.2 1.2e-10 41.6 0.0 3.6 3 0 0 3 3 3 2 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 EHT98266.1 - 2e-14 54.5 1.5 7e-07 30.3 0.1 3.8 3 1 0 3 3 3 2 Cytochrome c GMC_oxred_N PF00732.19 EHT98266.1 - 2.8e-10 40.0 0.0 3.8e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase DAO PF01266.24 EHT98266.1 - 6.8e-08 32.5 3.6 3.3e-05 23.7 0.4 3.0 5 0 0 5 5 4 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EHT98266.1 - 4.9e-06 25.9 3.2 0.00014 21.1 0.9 2.4 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 EHT98266.1 - 8.4e-05 21.8 0.3 0.00014 21.1 0.3 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EHT98266.1 - 9.1e-05 22.6 0.2 0.00032 20.9 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EHT98266.1 - 0.0001 22.8 0.4 0.026 15.1 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EHT98266.1 - 0.00054 19.3 0.2 0.0029 16.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EHT98266.1 - 0.00076 18.3 2.1 0.00076 18.3 0.5 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 EHT98266.1 - 0.0024 17.2 0.3 0.0024 17.2 0.3 1.6 2 0 0 2 2 2 1 FAD binding domain CCP_MauG PF03150.14 EHT98266.1 - 0.0037 17.9 0.0 1.3 9.6 0.0 2.6 2 0 0 2 2 2 1 Di-haem cytochrome c peroxidase FAD_oxidored PF12831.7 EHT98266.1 - 0.0042 16.5 1.7 0.029 13.7 1.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase ApbA PF02558.16 EHT98266.1 - 0.024 14.3 0.1 0.049 13.3 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Cytochrom_C550 PF14495.6 EHT98266.1 - 0.037 13.7 0.2 0.17 11.6 0.0 2.3 3 0 0 3 3 2 0 Cytochrome c-550 domain GIDA PF01134.22 EHT98266.1 - 0.05 12.7 0.1 0.073 12.1 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A CytoC_RC PF02276.18 EHT98266.1 - 0.082 12.3 0.2 0.78 9.1 0.0 2.1 2 0 0 2 2 2 0 Photosynthetic reaction centre cytochrome C subunit Cytochrome_C7 PF14522.6 EHT98266.1 - 0.093 12.7 0.1 22 5.2 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c Paired_CXXCH_1 PF09699.10 EHT98266.1 - 0.12 12.2 1.4 7.5 6.4 0.1 2.4 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) F420_oxidored PF03807.17 EHT98266.1 - 0.14 12.7 0.0 0.37 11.4 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF3836 PF12930.7 EHT98266.1 - 0.16 11.8 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF3836) GSu_C4xC__C2xCH PF09698.10 EHT98266.1 - 0.16 12.7 5.1 1.2 9.9 0.2 3.0 3 0 0 3 3 2 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) 3HCDH_N PF02737.18 EHT98266.1 - 0.24 11.2 0.1 0.45 10.4 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GGDEF PF00990.21 EHT98267.1 - 5.4e-48 162.8 0.0 1.1e-47 161.7 0.0 1.6 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain dCache_1 PF02743.18 EHT98267.1 - 1.8e-17 63.9 0.5 7e-17 62.0 0.1 1.9 2 0 0 2 2 2 1 Cache domain DUF4381 PF14316.6 EHT98267.1 - 0.059 13.6 5.8 10 6.4 0.7 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) POTRA_2 PF08479.11 EHT98267.1 - 0.082 12.8 0.1 0.24 11.3 0.1 1.7 1 0 0 1 1 1 0 POTRA domain, ShlB-type Nitroreductase PF00881.24 EHT98268.1 - 1.1e-21 77.7 0.5 1.7e-20 73.8 0.5 2.2 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 EHT98268.1 - 0.02 14.5 0.3 0.25 10.9 0.3 2.7 1 1 2 3 3 3 0 Putative TM nitroreductase Neprosin_AP PF14365.6 EHT98268.1 - 0.1 13.1 0.1 0.21 12.1 0.1 1.4 1 0 0 1 1 1 0 Neprosin activation peptide ABC_tran PF00005.27 EHT98269.1 - 2.6e-33 115.4 0.0 4.1e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 EHT98269.1 - 4.2e-08 33.2 0.0 9.3e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 TOBE domain AAA_21 PF13304.6 EHT98269.1 - 4.5e-07 30.0 0.1 0.0054 16.6 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EHT98269.1 - 8.3e-05 23.0 0.3 0.00016 22.1 0.3 1.5 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 EHT98269.1 - 0.00012 21.6 0.2 0.0043 16.5 0.2 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EHT98269.1 - 0.00015 21.8 0.0 0.00034 20.6 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_33 PF13671.6 EHT98269.1 - 0.0004 20.6 0.0 0.001 19.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EHT98269.1 - 0.00057 19.6 0.1 0.0038 16.9 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain OB_MalK PF17912.1 EHT98269.1 - 0.0026 18.5 0.2 0.011 16.5 0.1 2.3 2 1 0 2 2 1 1 MalK OB fold domain AAA_22 PF13401.6 EHT98269.1 - 0.0046 17.2 0.1 0.0082 16.4 0.1 1.5 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 EHT98269.1 - 0.0069 16.3 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain MMR_HSR1 PF01926.23 EHT98269.1 - 0.013 15.5 0.0 0.057 13.5 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 EHT98269.1 - 0.014 15.3 0.2 0.039 13.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 EHT98269.1 - 0.028 14.9 0.0 0.058 13.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EHT98269.1 - 0.032 13.8 0.3 0.22 11.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EHT98269.1 - 0.032 14.1 0.0 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 EHT98269.1 - 0.041 13.6 0.1 0.092 12.4 0.1 1.7 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.6 EHT98269.1 - 0.046 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EHT98269.1 - 0.047 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 EHT98269.1 - 0.052 12.7 0.0 0.09 12.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Adeno_IVa2 PF02456.15 EHT98269.1 - 0.1 11.4 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_23 PF13476.6 EHT98269.1 - 0.1 13.1 0.1 0.19 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain TOBE PF03459.17 EHT98269.1 - 0.11 12.7 0.0 3.4 8.0 0.0 2.5 2 0 0 2 2 2 0 TOBE domain AAA_14 PF13173.6 EHT98269.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain SBP_bac_8 PF13416.6 EHT98270.1 - 1.6e-11 44.6 0.2 1.9e-11 44.3 0.2 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 EHT98270.1 - 1.2e-10 41.8 0.3 1.5e-10 41.5 0.3 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 EHT98270.1 - 0.049 13.4 0.2 0.075 12.8 0.2 1.5 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 EHT98271.1 - 1.4e-23 84.1 6.6 1.4e-23 84.1 6.6 1.4 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 EHT98271.1 - 3e-10 40.6 5.5 3e-10 40.6 5.5 1.4 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein ABATE PF07336.11 EHT98271.1 - 0.86 10.3 3.7 6.8 7.4 3.7 2.1 1 1 0 1 1 1 0 Putative stress-induced transcription regulator BPD_transp_1 PF00528.22 EHT98272.1 - 1.2e-14 54.5 18.7 1.2e-14 54.5 18.7 2.0 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component RII_binding_1 PF10522.9 EHT98272.1 - 0.018 15.2 0.1 0.043 14.0 0.1 1.6 1 0 0 1 1 1 0 RII binding domain GerA PF03323.13 EHT98272.1 - 0.049 12.1 1.2 0.078 11.4 1.2 1.3 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein BPD_transp_1 PF00528.22 EHT98273.1 - 5e-07 29.6 30.1 8.1e-06 25.7 30.1 2.3 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Metallophos PF00149.28 EHT98274.1 - 5.9e-09 36.7 0.1 7.1e-09 36.5 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EHT98274.1 - 0.0045 17.2 0.0 0.0052 17.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DDE_3 PF13358.6 EHT98275.1 - 1.1e-22 80.3 0.0 1.9e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 EHT98275.1 - 1.1e-10 41.0 1.0 3.6e-09 36.2 0.1 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 EHT98275.1 - 4.1e-09 36.9 1.1 2.8e-08 34.3 0.3 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 EHT98275.1 - 4e-07 30.0 1.2 1.1e-06 28.6 0.3 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHT98275.1 - 1.4e-05 25.1 0.3 0.0002 21.4 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_33 PF13592.6 EHT98275.1 - 6e-05 22.6 5.4 8.3e-05 22.1 0.5 3.0 3 0 0 3 3 3 1 Winged helix-turn helix LZ_Tnp_IS481 PF13011.6 EHT98275.1 - 0.029 14.9 0.2 0.061 13.8 0.2 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 HTH_38 PF13936.6 EHT98275.1 - 0.052 13.3 0.6 0.16 11.8 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain AhpC-TSA PF00578.21 EHT98276.1 - 2.7e-25 88.7 0.0 3.5e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EHT98276.1 - 2.7e-20 72.6 0.3 3.4e-20 72.3 0.3 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 EHT98276.1 - 0.0043 17.1 0.0 0.0065 16.6 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme CN_hydrolase PF00795.22 EHT98276.1 - 0.013 14.8 0.1 1.3 8.3 0.1 2.2 1 1 1 2 2 2 0 Carbon-nitrogen hydrolase Thioredoxin_7 PF13899.6 EHT98277.1 - 5.1e-15 55.4 0.0 9.7e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like DsbD PF02683.15 EHT98277.1 - 1.5e-08 34.8 17.6 1.5e-08 34.8 17.6 1.8 2 0 0 2 2 2 1 Cytochrome C biogenesis protein transmembrane region Redoxin PF08534.10 EHT98277.1 - 0.00048 19.9 0.1 0.0008 19.1 0.1 1.3 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.6 EHT98277.1 - 0.00063 20.2 0.0 0.001 19.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredox_DsbH PF03190.15 EHT98277.1 - 0.0012 18.8 0.0 0.002 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin PF00085.20 EHT98277.1 - 0.0076 16.2 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Fumarate_red_C PF02300.17 EHT98277.1 - 0.012 15.7 0.6 0.012 15.7 0.6 2.2 2 0 0 2 2 2 0 Fumarate reductase subunit C CD225 PF04505.12 EHT98277.1 - 0.19 11.9 0.3 0.19 11.9 0.3 2.6 3 0 0 3 3 3 0 Interferon-induced transmembrane protein Asp_Glu_race PF01177.22 EHT98278.1 - 1.2e-55 188.8 0.0 1.3e-55 188.7 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Pantoate_transf PF02548.15 EHT98278.1 - 0.037 13.4 0.1 0.14 11.5 0.1 1.8 1 1 1 2 2 2 0 Ketopantoate hydroxymethyltransferase Peripla_BP_1 PF00532.21 EHT98278.1 - 0.11 11.9 0.0 1 8.7 0.0 2.3 2 1 0 2 2 2 0 Periplasmic binding proteins and sugar binding domain of LacI family Cupin_3 PF05899.12 EHT98279.1 - 2.6e-16 59.1 0.0 3.9e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 EHT98279.1 - 8.6e-05 22.2 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Ppnp PF06865.11 EHT98279.1 - 0.014 15.8 0.0 0.018 15.4 0.0 1.2 1 0 0 1 1 1 0 Pyrimidine/purine nucleoside phosphorylase AraC_binding PF02311.19 EHT98279.1 - 0.031 14.2 0.0 0.039 13.8 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain HTH_Tnp_1 PF01527.20 EHT98280.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT98280.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT98280.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT98280.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHT98281.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHT98282.1 - 2.6e-97 325.7 3.5 1.2e-96 323.5 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT98282.1 - 3.4e-16 59.2 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT98282.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT98282.1 - 1.2e-11 45.2 9.0 2.6e-11 44.1 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHT98282.1 - 0.017 14.9 6.4 0.027 14.3 6.4 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Phage_HK97_TLTM PF06120.11 EHT98282.1 - 0.022 14.0 1.7 0.042 13.0 1.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHT98282.1 - 0.022 15.1 4.3 0.091 13.1 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain FUSC PF04632.12 EHT98282.1 - 0.038 12.5 6.8 0.06 11.9 6.8 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 EHT98282.1 - 0.04 13.5 2.2 0.047 13.2 0.8 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Tho2 PF11262.8 EHT98282.1 - 0.057 12.6 0.5 0.094 11.9 0.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Troponin PF00992.20 EHT98282.1 - 0.062 13.6 3.0 0.11 12.8 3.0 1.3 1 0 0 1 1 1 0 Troponin LXG PF04740.12 EHT98282.1 - 0.11 12.3 2.5 0.32 10.7 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily UME PF08064.13 EHT98282.1 - 0.15 12.0 0.5 21 5.1 0.0 3.1 2 1 1 3 3 3 0 UME (NUC010) domain ERM PF00769.19 EHT98282.1 - 0.16 11.8 10.8 0.26 11.1 10.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HalX PF08663.10 EHT98282.1 - 0.23 11.8 3.1 0.59 10.5 3.1 1.7 1 0 0 1 1 1 0 HalX domain DHR10 PF18595.1 EHT98282.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Zn-ribbon_8 PF09723.10 EHT98282.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF1192 PF06698.11 EHT98282.1 - 0.53 10.4 5.3 3.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHT98282.1 - 1.1 8.4 3.1 1.7 7.8 3.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHT98282.1 - 2.8 7.4 7.9 6.1 6.3 7.9 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHT98282.1 - 3.3 8.1 7.9 6.7 7.0 7.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 EHT98282.1 - 7.5 7.3 8.7 7.7 7.2 1.0 3.0 1 1 1 2 2 2 0 SlyX DsbB PF02600.16 EHT98284.1 - 1.3e-12 48.4 9.3 1.3e-12 48.4 9.3 2.8 2 1 1 3 3 3 2 Disulfide bond formation protein DsbB Phytochelatin PF05023.14 EHT98285.1 - 1.3e-50 171.5 0.0 1.7e-50 171.2 0.0 1.1 1 0 0 1 1 1 1 Phytochelatin synthase Peptidase_C39_2 PF13529.6 EHT98285.1 - 0.0021 18.6 0.0 0.12 12.9 0.0 2.2 1 1 0 1 1 1 1 Peptidase_C39 like family G_glu_transpept PF01019.21 EHT98286.1 - 1.8e-95 320.7 0.0 2.1e-95 320.4 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase G_glu_transpept PF01019.21 EHT98287.1 - 1.9e-69 234.8 0.0 2.2e-69 234.6 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Asp_Glu_race PF01177.22 EHT98288.1 - 2.1e-31 109.5 0.1 2.4e-31 109.3 0.1 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase PA PF02225.22 EHT98288.1 - 0.076 13.0 0.0 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 PA domain MFS_1 PF07690.16 EHT98289.1 - 2.1e-22 79.5 16.4 2.4e-22 79.3 16.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EHT98289.1 - 1e-10 41.1 3.5 1.2e-10 40.8 3.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EHT98289.1 - 0.00052 18.6 3.4 0.00059 18.4 3.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 EHT98289.1 - 0.0013 17.4 3.5 0.0022 16.6 3.5 1.4 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_3 PF05977.13 EHT98289.1 - 0.038 12.4 3.1 0.042 12.3 3.1 1.1 1 0 0 1 1 1 0 Transmembrane secretion effector ATP-grasp_4 PF13535.6 EHT98290.1 - 2.4e-07 30.5 0.0 5.1e-07 29.4 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EHT98290.1 - 0.0003 20.9 0.0 0.0005 20.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_N PF18130.1 EHT98290.1 - 0.00032 21.2 0.0 0.00075 20.0 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp N-terminal domain tRNA-synt_2 PF00152.20 EHT98291.1 - 3e-06 26.5 0.2 3.2e-06 26.4 0.2 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DDE_Tnp_1 PF01609.21 EHT98292.1 - 2.9e-25 89.2 0.9 3.4e-25 89.0 0.9 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_5 PF13737.6 EHT98292.1 - 2.1e-13 50.6 0.0 4.8e-12 46.2 0.0 2.3 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1_5 PF13737.6 EHT98293.1 - 2.2e-25 89.1 0.0 2.6e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_5 PF13737.6 EHT98294.1 - 2.2e-25 89.1 0.0 2.6e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 EHT98295.1 - 2.9e-25 89.2 0.9 3.4e-25 89.0 0.9 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_5 PF13737.6 EHT98295.1 - 2.1e-13 50.6 0.0 4.8e-12 46.2 0.0 2.3 2 0 0 2 2 2 1 Transposase DDE domain CesT PF05932.13 EHT98296.1 - 0.13 12.4 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 Tir chaperone protein (CesT) family Transglut_core PF01841.19 EHT98297.1 - 0.071 13.6 0.3 0.18 12.3 0.2 1.9 1 1 0 1 1 1 0 Transglutaminase-like superfamily IMS_C PF11799.8 EHT98298.1 - 0.12 13.1 0.0 0.12 13.1 0.0 1.0 1 0 0 1 1 1 0 impB/mucB/samB family C-terminal domain HTH_Tnp_1 PF01527.20 EHT98300.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT98300.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT98300.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT98300.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHT98301.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHT98302.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT98302.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT98302.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT98302.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix DDE_3 PF13358.6 EHT98303.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHT98303.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHT98303.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHT98303.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHT98303.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHT98303.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHT98303.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHT98303.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 SSB PF00436.25 EHT98304.1 - 1.2e-42 144.1 1.0 1.6e-42 143.7 1.0 1.2 1 0 0 1 1 1 1 Single-strand binding protein family DUF4792 PF16040.5 EHT98304.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4792) UvrA_inter PF17760.1 EHT98305.1 - 3.9e-39 133.1 0.0 1.3e-38 131.4 0.0 2.0 1 0 0 1 1 1 1 UvrA interaction domain UvrA_DNA-bind PF17755.1 EHT98305.1 - 5.5e-36 123.3 0.0 1.2e-34 119.0 0.0 2.7 3 0 0 3 3 2 1 UvrA DNA-binding domain ABC_tran PF00005.27 EHT98305.1 - 1.1e-22 81.1 0.0 1.4e-05 25.6 0.0 5.0 4 1 0 4 4 4 4 ABC transporter SMC_N PF02463.19 EHT98305.1 - 1.9e-11 43.8 0.1 0.022 14.2 0.0 4.2 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EHT98305.1 - 8.4e-08 31.9 0.4 0.0013 18.5 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EHT98305.1 - 1.3e-07 32.2 0.2 0.023 15.1 0.1 3.6 3 1 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 EHT98305.1 - 1.3e-05 25.2 0.1 0.049 13.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase DnaJ_CXXCXGXG PF00684.19 EHT98305.1 - 1.6e-05 25.2 2.4 0.023 15.0 0.2 3.5 3 0 0 3 3 3 1 DnaJ central domain AAA_22 PF13401.6 EHT98305.1 - 4.1e-05 23.9 1.4 0.92 9.8 0.0 4.0 5 0 0 5 5 3 2 AAA domain AAA_23 PF13476.6 EHT98305.1 - 0.00025 21.6 6.7 0.42 11.1 0.1 3.3 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 EHT98305.1 - 0.00055 20.5 0.0 2.7 8.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EHT98305.1 - 0.0011 18.6 0.3 0.31 10.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 EHT98305.1 - 0.0016 18.6 0.0 2.8 8.1 0.0 3.1 3 0 0 3 3 2 1 AAA domain cobW PF02492.19 EHT98305.1 - 0.0025 17.4 0.5 0.2 11.2 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain APS_kinase PF01583.20 EHT98305.1 - 0.0042 17.0 0.1 1.5 8.7 0.0 2.9 2 0 0 2 2 2 1 Adenylylsulphate kinase DUF2083 PF09856.9 EHT98305.1 - 0.0045 16.9 0.0 0.014 15.3 0.0 1.8 1 0 0 1 1 1 1 Predicted transcriptional regulator (DUF2083) T2SSE PF00437.20 EHT98305.1 - 0.0055 15.8 0.3 2.6 7.0 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein Viral_helicase1 PF01443.18 EHT98305.1 - 0.0059 16.4 0.0 0.4 10.4 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 EHT98305.1 - 0.0064 16.4 0.0 1.1 9.1 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 EHT98305.1 - 0.0083 15.9 0.1 7.3 6.3 0.0 3.4 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.9 EHT98305.1 - 0.0085 15.4 0.0 0.94 8.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_21 PF13304.6 EHT98305.1 - 0.011 15.5 7.2 0.68 9.7 0.0 3.9 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system ATPase PF06745.13 EHT98305.1 - 0.019 14.3 0.0 5.3 6.3 0.0 2.4 2 0 0 2 2 2 0 KaiC MeaB PF03308.16 EHT98305.1 - 0.026 13.5 0.5 1.7 7.6 0.0 2.9 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_14 PF13173.6 EHT98305.1 - 0.037 14.1 0.0 15 5.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 EHT98305.1 - 0.067 13.3 0.1 3.5 7.7 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATPase_2 PF01637.18 EHT98305.1 - 0.073 13.0 0.0 8.5 6.2 0.0 2.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EHT98305.1 - 0.077 12.7 0.2 8.6 6.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 EHT98305.1 - 0.14 12.4 0.0 18 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EHT98305.1 - 0.14 11.6 0.1 25 4.3 0.0 2.8 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 EHT98305.1 - 0.95 9.4 2.8 6.2 6.7 0.1 3.1 4 0 0 4 4 3 0 NTPase Zn-ribbon_8 PF09723.10 EHT98305.1 - 3.6 7.8 9.6 3.4 7.9 0.3 3.6 3 0 0 3 3 3 0 Zinc ribbon domain ADH_N PF08240.12 EHT98306.1 - 1.7e-26 92.2 3.6 3.4e-26 91.3 3.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EHT98306.1 - 1.1e-21 77.2 0.0 1.9e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EHT98306.1 - 9.5e-06 25.1 0.1 1.6e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EHT98306.1 - 1.5e-05 24.4 0.0 2.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 EHT98306.1 - 0.00064 20.8 0.0 0.0011 20.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_2 PF03446.15 EHT98306.1 - 0.0019 18.4 0.1 0.0034 17.6 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Methyltransf_25 PF13649.6 EHT98306.1 - 0.03 15.0 0.5 0.21 12.3 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_11 PF08241.12 EHT98306.1 - 0.05 14.3 0.0 0.15 12.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Oxidored_nitro PF00148.19 EHT98306.1 - 0.058 12.1 0.0 0.087 11.5 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase 3HCDH_N PF02737.18 EHT98306.1 - 0.075 12.9 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YjbR PF04237.13 EHT98307.1 - 1.5e-15 57.5 0.0 1.7e-15 57.3 0.0 1.0 1 0 0 1 1 1 1 YjbR UPF0047 PF01894.17 EHT98308.1 - 1.3e-34 118.8 0.0 1.4e-34 118.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 FlgD_ig PF13860.6 EHT98309.1 - 0.019 14.8 0.0 0.05 13.5 0.0 1.7 1 0 0 1 1 1 0 FlgD Ig-like domain DDE_Tnp_1_5 PF13737.6 EHT98311.1 - 1.2e-44 151.2 0.0 3.1e-44 149.9 0.0 1.7 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 EHT98311.1 - 1.9e-24 86.5 1.0 2.3e-24 86.2 1.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain Peripla_BP_2 PF01497.18 EHT98312.1 - 3.7e-28 98.7 0.3 4.6e-28 98.4 0.3 1.1 1 0 0 1 1 1 1 Periplasmic binding protein KdpD PF02702.17 EHT98312.1 - 0.026 14.0 0.2 2.7 7.4 0.0 2.3 2 0 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain SBP_bac_11 PF13531.6 EHT98313.1 - 1.5e-37 129.5 0.0 1.7e-37 129.3 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein HTS PF04204.16 EHT98314.1 - 1.1e-131 438.2 0.0 1.3e-131 438.0 0.0 1.0 1 0 0 1 1 1 1 Homoserine O-succinyltransferase Malate_synthase PF01274.22 EHT98315.1 - 6.5e-198 658.3 0.0 7.2e-198 658.1 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.14 EHT98315.1 - 0.00011 21.4 0.0 0.00022 20.4 0.0 1.6 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Rota_VP2 PF05087.12 EHT98315.1 - 0.086 11.0 0.1 0.12 10.5 0.1 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein ICL PF00463.21 EHT98316.1 - 2.2e-108 363.0 0.5 2.8e-58 197.7 0.0 2.0 1 1 1 2 2 2 2 Isocitrate lyase family PEP_mutase PF13714.6 EHT98316.1 - 5.2e-16 58.8 0.1 1.1e-15 57.8 0.1 1.5 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ETC_C1_NDUFA4 PF04800.12 EHT98316.1 - 0.1 12.8 1.0 0.28 11.5 0.7 1.9 2 0 0 2 2 2 0 ETC complex I subunit conserved region AceK PF06315.11 EHT98317.1 - 1.1e-230 766.9 0.0 1.3e-230 766.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate dehydrogenase kinase/phosphatase (AceK) IclR PF01614.18 EHT98319.1 - 5.3e-40 136.2 0.0 8.3e-40 135.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 EHT98319.1 - 8.2e-18 63.9 2.2 8.2e-18 63.9 2.2 1.8 2 0 0 2 2 2 1 IclR helix-turn-helix domain MarR_2 PF12802.7 EHT98319.1 - 0.00011 22.0 0.3 0.00028 20.7 0.3 1.7 1 0 0 1 1 1 1 MarR family MarR PF01047.22 EHT98319.1 - 0.0018 18.2 0.1 0.0035 17.2 0.1 1.4 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 EHT98319.1 - 0.002 18.4 0.1 0.0046 17.3 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulator HTH_24 PF13412.6 EHT98319.1 - 0.0054 16.3 0.0 0.0098 15.4 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 EHT98319.1 - 0.032 14.2 0.1 0.094 12.7 0.1 1.8 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_20 PF12840.7 EHT98319.1 - 0.037 14.1 0.1 0.16 12.1 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_47 PF16221.5 EHT98319.1 - 0.041 13.5 0.1 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 winged helix-turn-helix TrmB PF01978.19 EHT98319.1 - 0.077 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB YjbH PF06082.11 EHT98320.1 - 3.3e-267 888.6 12.9 3.8e-267 888.5 12.9 1.0 1 0 0 1 1 1 1 Exopolysaccharide biosynthesis protein YbjH Caps_synth_GfcC PF06251.11 EHT98321.1 - 9.1e-68 228.3 0.1 1e-67 228.1 0.1 1.0 1 0 0 1 1 1 1 Capsule biosynthesis GfcC ssDBP_DBD PF18361.1 EHT98321.1 - 0.2 11.8 0.0 0.31 11.2 0.0 1.3 1 0 0 1 1 1 0 Single stranded DNA-binding protein ss DNA binding domain ScsC_N PF18312.1 EHT98321.1 - 2.9 7.8 0.0 2.9 7.8 0.0 2.9 3 0 0 3 3 3 0 Copper resistance protein ScsC N-terminal domain YjbF PF11102.8 EHT98322.1 - 3.9e-66 222.4 0.2 4.5e-66 222.2 0.2 1.0 1 0 0 1 1 1 1 Group 4 capsule polysaccharide lipoprotein gfcB, YjbF YjbE PF11106.8 EHT98323.1 - 9.4e-29 99.5 27.7 1e-28 99.3 27.7 1.0 1 0 0 1 1 1 1 Exopolysaccharide production protein YjbE PGI PF00342.19 EHT98324.1 - 1.9e-255 848.0 0.1 2.2e-255 847.8 0.1 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase AA_kinase PF00696.28 EHT98325.1 - 7.1e-49 166.6 0.8 1e-48 166.1 0.8 1.2 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 EHT98325.1 - 1.9e-06 27.5 0.0 7.6e-06 25.6 0.0 2.0 2 0 0 2 2 2 1 ACT domain ACT_7 PF13840.6 EHT98325.1 - 9.8e-06 25.3 0.0 0.037 13.8 0.0 3.0 2 0 0 2 2 2 2 ACT domain T2SS-T3SS_pil_N PF13629.6 EHT98325.1 - 0.08 12.7 0.1 0.25 11.1 0.1 1.8 1 0 0 1 1 1 0 Pilus formation protein N terminal region SBF PF01758.16 EHT98326.1 - 5.6e-37 127.3 18.5 9.1e-37 126.6 18.5 1.3 1 0 0 1 1 1 1 Sodium Bile acid symporter family SBF_like PF13593.6 EHT98326.1 - 1.5e-20 73.7 18.1 1.7e-20 73.6 18.1 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Na_Pi_cotrans PF02690.15 EHT98327.1 - 4.6e-44 149.9 21.8 1.6e-35 122.2 9.0 2.3 2 0 0 2 2 2 2 Na+/Pi-cotransporter PhoU PF01895.19 EHT98327.1 - 2e-08 34.6 3.1 2.2e-07 31.2 0.8 2.5 2 0 0 2 2 2 1 PhoU domain Phosphodiest PF01663.22 EHT98328.1 - 1.6e-15 57.6 0.9 1.4e-13 51.2 0.9 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 EHT98328.1 - 0.00029 20.3 0.0 0.0017 17.8 0.0 2.0 1 1 0 1 1 1 1 Metalloenzyme superfamily PglZ PF08665.12 EHT98328.1 - 0.017 15.2 0.0 0.37 10.9 0.0 2.4 2 1 1 3 3 3 0 PglZ domain PsiE PF06146.12 EHT98329.1 - 7.6e-16 58.3 2.2 7.6e-16 58.3 2.2 1.8 1 1 1 2 2 2 1 Phosphate-starvation-inducible E Gram_pos_anchor PF00746.21 EHT98329.1 - 1.9 8.5 3.7 55 3.8 0.0 3.2 3 0 0 3 3 3 0 LPXTG cell wall anchor motif Chor_lyase PF04345.13 EHT98330.1 - 3.5e-39 134.2 0.0 3.8e-39 134.0 0.0 1.0 1 0 0 1 1 1 1 Chorismate lyase UbiA PF01040.18 EHT98331.1 - 6.1e-66 222.3 25.0 7.5e-66 222.0 25.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF2518 PF10726.9 EHT98331.1 - 5.9 6.5 6.7 1.2 8.7 0.6 2.3 2 0 0 2 2 2 0 Protein of function (DUF2518) COX2-transmemb PF09125.10 EHT98331.1 - 8.3 6.3 6.6 6.4 6.7 0.2 3.2 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane Acyltransferase PF01553.21 EHT98332.1 - 4.1e-24 84.7 0.0 7.9e-24 83.8 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase DUF3292 PF11696.8 EHT98332.1 - 0.097 11.0 0.1 0.2 10.0 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) DAGK_prokar PF01219.19 EHT98333.1 - 1.1e-36 124.7 3.3 1.3e-36 124.5 3.3 1.0 1 0 0 1 1 1 1 Prokaryotic diacylglycerol kinase LexA_DNA_bind PF01726.16 EHT98334.1 - 2e-29 101.1 0.1 3.1e-29 100.5 0.1 1.3 1 0 0 1 1 1 1 LexA DNA binding domain Peptidase_S24 PF00717.23 EHT98334.1 - 5.6e-14 51.9 0.5 8.2e-14 51.3 0.5 1.3 1 0 0 1 1 1 1 Peptidase S24-like Rrf2 PF02082.20 EHT98334.1 - 0.0016 18.7 0.0 0.0032 17.8 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator HTH_20 PF12840.7 EHT98334.1 - 0.0026 17.8 0.0 0.005 16.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain GntR PF00392.21 EHT98334.1 - 0.0034 17.0 0.1 0.03 14.0 0.1 2.6 2 1 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 EHT98334.1 - 0.0051 16.8 0.1 0.012 15.6 0.1 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain CSD2 PF17876.1 EHT98334.1 - 0.13 12.4 0.2 0.26 11.5 0.2 1.4 1 0 0 1 1 1 0 Cold shock domain MatE PF01554.18 EHT98335.1 - 2.5e-39 134.5 32.2 3.3e-29 101.6 13.6 2.5 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 EHT98335.1 - 1.6e-07 31.5 10.6 1.6e-07 31.5 10.6 4.9 3 3 2 5 5 5 1 Polysaccharide biosynthesis C-terminal domain Tweety PF04906.13 EHT98335.1 - 0.053 12.2 4.4 0.12 11.0 4.4 1.5 1 0 0 1 1 1 0 Tweety CsbD PF05532.12 EHT98336.1 - 6.3e-23 80.4 8.0 7.6e-23 80.2 8.0 1.1 1 0 0 1 1 1 1 CsbD-like COX4 PF02936.14 EHT98336.1 - 0.079 13.0 1.6 0.086 12.9 0.4 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase subunit IV FUR PF01475.19 EHT98337.1 - 2.8e-13 50.0 2.4 7.2e-13 48.7 0.0 2.0 1 1 1 2 2 2 1 Ferric uptake regulator family MarR PF01047.22 EHT98337.1 - 0.011 15.6 0.0 0.034 14.1 0.0 1.8 1 1 0 1 1 1 0 MarR family TrmB PF01978.19 EHT98337.1 - 0.04 13.8 0.0 0.072 13.0 0.0 1.5 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.20 EHT98337.1 - 0.055 13.4 0.0 0.37 10.7 0.0 2.2 1 1 0 1 1 1 0 Bacterial regulatory protein, arsR family TraF_2 PF13729.6 EHT98338.1 - 2.5e-81 273.1 3.7 3.4e-81 272.7 3.7 1.2 1 0 0 1 1 1 1 F plasmid transfer operon, TraF, protein PorP_SprF PF11751.8 EHT98338.1 - 1.6e-05 24.6 2.0 2.8e-05 23.8 0.4 1.9 2 0 0 2 2 2 1 Type IX secretion system membrane protein PorP/SprF OMP_b-brl PF13505.6 EHT98338.1 - 6e-05 23.2 16.8 0.0089 16.2 0.5 3.7 1 1 1 2 2 2 2 Outer membrane protein beta-barrel domain OmpA_membrane PF01389.17 EHT98338.1 - 0.0064 16.2 0.1 0.026 14.2 0.0 1.9 2 0 0 2 2 2 1 OmpA-like transmembrane domain Toluene_X PF03349.16 EHT98338.1 - 0.0074 14.9 6.1 0.087 11.4 0.3 2.8 2 1 0 2 2 2 2 Outer membrane protein transport protein (OMPP1/FadL/TodX) Dus PF01207.17 EHT98339.1 - 2.3e-91 306.1 0.0 2.7e-91 305.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 EHT98339.1 - 0.15 11.5 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein Phageshock_PspG PF09583.10 EHT98340.1 - 6.9e-23 80.7 22.5 7.8e-23 80.5 22.5 1.0 1 0 0 1 1 1 1 Phage shock protein G (Phageshock_PspG) SpoIIM PF01944.17 EHT98340.1 - 0.0028 17.7 2.4 0.0028 17.7 2.4 1.0 1 0 0 1 1 1 1 Stage II sporulation protein M VirB3 PF05101.13 EHT98340.1 - 0.059 13.6 13.4 0.028 14.6 10.4 1.8 1 1 1 2 2 2 0 Type IV secretory pathway, VirB3-like protein CbiQ PF02361.16 EHT98340.1 - 0.15 11.6 8.4 0.19 11.3 8.4 1.0 1 0 0 1 1 1 0 Cobalt transport protein DUF2628 PF10947.8 EHT98340.1 - 1.1 9.7 13.8 1.7 9.0 13.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) TraL PF07178.11 EHT98340.1 - 5.3 7.6 14.0 0.3 11.6 2.5 2.1 1 1 1 2 2 2 0 TraL protein DUF2244 PF10003.9 EHT98340.1 - 6.3 6.5 12.8 11 5.7 12.8 1.5 1 1 0 1 1 1 0 Integral membrane protein (DUF2244) ADH_zinc_N PF00107.26 EHT98341.1 - 2.7e-27 95.3 0.9 3.5e-27 95.0 0.1 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EHT98341.1 - 1.4e-16 61.8 0.0 2.2e-16 61.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EHT98341.1 - 4.7e-08 32.9 0.0 1.5e-07 31.3 0.0 1.9 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain DnaB_C PF03796.15 EHT98342.1 - 3.3e-111 370.7 0.4 4.6e-111 370.2 0.4 1.2 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain DnaB PF00772.21 EHT98342.1 - 1e-35 121.9 0.0 2.2e-35 120.8 0.0 1.6 1 0 0 1 1 1 1 DnaB-like helicase N terminal domain AAA_25 PF13481.6 EHT98342.1 - 7.4e-10 38.7 0.0 1.2e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EHT98342.1 - 0.00021 20.7 0.0 0.00065 19.1 0.0 1.8 1 0 0 1 1 1 1 KaiC AAA_33 PF13671.6 EHT98342.1 - 0.0039 17.3 0.0 0.03 14.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain AsnC_trans_reg PF01037.21 EHT98343.1 - 2.9e-18 65.6 0.4 4.8e-18 64.9 0.4 1.4 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_AsnC-type PF13404.6 EHT98343.1 - 6.2e-13 48.3 0.3 1.4e-12 47.2 0.3 1.7 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 EHT98343.1 - 1.1e-11 44.0 2.2 1.3e-11 43.8 1.0 1.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 EHT98343.1 - 0.00044 20.2 0.4 0.092 12.7 0.0 2.5 2 1 0 2 2 2 2 Crp-like helix-turn-helix domain MarR PF01047.22 EHT98343.1 - 0.004 17.1 0.5 0.014 15.3 0.1 2.0 2 1 0 2 2 2 1 MarR family Rrf2 PF02082.20 EHT98343.1 - 0.054 13.8 0.3 8.8 6.8 0.1 2.2 2 0 0 2 2 2 0 Transcriptional regulator YitT_membrane PF02588.15 EHT98344.1 - 7.8e-33 113.6 16.5 9.3e-33 113.3 16.5 1.0 1 0 0 1 1 1 1 Uncharacterised 5xTM membrane BCR, YitT family COG1284 Aminotran_1_2 PF00155.21 EHT98345.1 - 2e-83 280.6 0.0 2.2e-83 280.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Polysacc_synt_C PF14667.6 EHT98346.1 - 2.1e-06 27.8 5.1 2.1e-06 27.8 5.1 3.8 2 1 1 3 3 3 1 Polysaccharide biosynthesis C-terminal domain S1FA PF04689.13 EHT98346.1 - 0.14 12.4 1.3 0.31 11.2 0.1 2.2 2 0 0 2 2 2 0 DNA binding protein S1FA ATPgrasp_TupA PF14305.6 EHT98347.1 - 4.8e-39 134.6 0.1 6.2e-39 134.2 0.1 1.1 1 0 0 1 1 1 1 TupA-like ATPgrasp YjcB PF15940.5 EHT98348.1 - 3.6e-42 142.4 5.7 4e-42 142.3 5.7 1.0 1 0 0 1 1 1 1 Family of unknown function Voltage_CLC PF00654.20 EHT98348.1 - 0.0043 16.4 0.1 0.0052 16.1 0.1 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel HTH_18 PF12833.7 EHT98349.1 - 1.8e-22 79.4 3.1 1.8e-22 79.4 3.1 1.8 2 1 1 3 3 3 2 Helix-turn-helix domain HTH_AraC PF00165.23 EHT98349.1 - 2.2e-18 65.9 4.5 3.2e-12 46.2 0.7 2.5 3 0 0 3 3 3 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_3 PF01381.22 EHT98349.1 - 0.021 14.9 0.1 0.1 12.7 0.0 2.2 2 1 0 2 2 2 0 Helix-turn-helix CBM9_1 PF06452.11 EHT98349.1 - 0.088 12.7 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate family 9 binding domain-like MerR-DNA-bind PF09278.11 EHT98350.1 - 1.1e-14 54.7 0.2 1.5e-14 54.2 0.2 1.2 1 0 0 1 1 1 1 MerR, DNA binding MerR PF00376.23 EHT98350.1 - 9.5e-14 50.9 0.1 1.7e-13 50.1 0.1 1.4 1 0 0 1 1 1 1 MerR family regulatory protein MerR_1 PF13411.6 EHT98350.1 - 1.6e-12 47.3 0.0 2.4e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein HTH_24 PF13412.6 EHT98350.1 - 0.011 15.3 0.0 5.7 6.6 0.0 2.6 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 EHT98350.1 - 0.023 14.6 0.3 9.6 6.2 0.1 3.0 1 1 1 2 2 2 0 MarR family LPD22 PF18834.1 EHT98350.1 - 0.037 14.2 0.0 0.075 13.3 0.0 1.4 1 0 0 1 1 1 0 Large polyvalent protein associated domain 22 HTH_IclR PF09339.10 EHT98350.1 - 0.047 13.5 0.0 9.4 6.1 0.0 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain MarR PF01047.22 EHT98350.1 - 0.076 13.0 0.1 0.69 9.9 0.0 2.6 2 1 0 2 2 2 0 MarR family GST_N PF02798.20 EHT98351.1 - 6.1e-17 61.7 0.0 1.2e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EHT98351.1 - 4.7e-13 49.3 0.1 9.4e-13 48.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EHT98351.1 - 1.8e-12 47.4 0.0 8.4e-12 45.2 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EHT98351.1 - 5.6e-06 26.5 0.0 1.2e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EHT98351.1 - 4.1e-05 24.3 0.0 0.0002 22.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 EHT98351.1 - 0.00073 19.8 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_3 PF14497.6 EHT98351.1 - 0.0026 17.9 0.0 0.0068 16.6 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EHT98351.1 - 0.019 15.6 0.0 0.096 13.3 0.0 2.0 1 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EHT98351.1 - 0.028 14.4 0.0 0.064 13.3 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Xan_ur_permease PF00860.20 EHT98352.1 - 1.4e-79 267.6 47.5 1.9e-79 267.2 47.5 1.1 1 0 0 1 1 1 1 Permease family DUF3333 PF11812.8 EHT98352.1 - 1.7 8.8 7.7 0.68 10.1 1.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3333) Na_H_Exchanger PF00999.21 EHT98353.1 - 6.3e-69 232.6 32.2 7.4e-69 232.4 32.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF4271 PF14093.6 EHT98353.1 - 0.02 14.8 4.4 0.1 12.5 1.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4271) Pox_A9 PF04835.12 EHT98353.1 - 0.11 12.7 0.4 0.11 12.7 0.4 2.1 2 0 0 2 2 2 0 A9 protein conserved region Na_H_Exchanger PF00999.21 EHT98354.1 - 5e-08 32.1 2.2 5.6e-08 32.0 2.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family MARVEL PF01284.23 EHT98354.1 - 0.041 13.9 0.0 0.045 13.8 0.0 1.1 1 0 0 1 1 1 0 Membrane-associating domain DUF2970 PF11174.8 EHT98354.1 - 2.8 7.9 8.0 2.3 8.2 4.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) DDE_Tnp_IS66 PF03050.14 EHT98355.1 - 1.1e-97 326.9 4.1 3.8e-97 325.2 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT98355.1 - 5.3e-18 65.0 0.1 2.2e-17 63.0 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT98355.1 - 1.9e-13 50.6 1.5 4.3e-13 49.4 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT98355.1 - 1.2e-11 45.2 9.0 2.6e-11 44.1 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHT98355.1 - 0.017 14.9 6.4 0.027 14.3 6.4 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Phage_HK97_TLTM PF06120.11 EHT98355.1 - 0.021 14.0 1.7 0.042 13.0 1.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHT98355.1 - 0.022 15.1 4.3 0.091 13.1 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain FUSC PF04632.12 EHT98355.1 - 0.037 12.6 6.8 0.06 11.9 6.8 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 EHT98355.1 - 0.047 13.3 2.6 0.049 13.2 1.0 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Tho2 PF11262.8 EHT98355.1 - 0.056 12.6 0.5 0.094 11.9 0.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Troponin PF00992.20 EHT98355.1 - 0.061 13.6 3.0 0.11 12.8 3.0 1.3 1 0 0 1 1 1 0 Troponin LXG PF04740.12 EHT98355.1 - 0.1 12.3 2.5 0.32 10.7 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily UME PF08064.13 EHT98355.1 - 0.15 12.0 0.5 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain ERM PF00769.19 EHT98355.1 - 0.16 11.8 10.8 0.26 11.1 10.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HalX PF08663.10 EHT98355.1 - 0.22 11.9 3.1 0.59 10.5 3.1 1.7 1 0 0 1 1 1 0 HalX domain DHR10 PF18595.1 EHT98355.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Zn-ribbon_8 PF09723.10 EHT98355.1 - 0.43 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF1192 PF06698.11 EHT98355.1 - 0.54 10.4 5.3 3.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHT98355.1 - 1.1 8.4 3.1 1.7 7.8 3.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHT98355.1 - 2.8 7.5 7.9 6.1 6.3 7.9 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHT98355.1 - 3.3 8.1 7.9 6.7 7.0 7.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 EHT98355.1 - 7 7.4 8.7 7.7 7.2 1.0 3.1 1 1 1 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHT98356.1 - 8.6e-12 44.9 0.0 9.4e-12 44.7 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHT98357.1 - 2.7e-10 40.4 0.0 5.4e-10 39.4 0.0 1.5 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.6 EHT98357.1 - 0.0054 16.5 0.0 0.0072 16.1 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 EHT98357.1 - 0.027 14.6 0.0 0.044 13.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4296 PF14129.6 EHT98359.1 - 0.38 11.4 1.7 0.6 10.8 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4296) LysR_substrate PF03466.20 EHT98360.1 - 4.3e-42 143.9 4.4 5.9e-42 143.4 4.4 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EHT98360.1 - 2.8e-22 78.4 0.8 8.3e-22 76.9 0.8 1.9 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 EHT98360.1 - 0.012 15.4 0.1 0.025 14.4 0.1 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Fe_dep_repress PF01325.19 EHT98360.1 - 0.14 12.4 0.1 0.27 11.4 0.1 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain MarR PF01047.22 EHT98360.1 - 0.15 12.0 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 MarR family LrgA PF03788.14 EHT98361.1 - 6e-28 96.6 11.9 8.3e-28 96.2 11.9 1.2 1 0 0 1 1 1 1 LrgA family LrgB PF04172.16 EHT98362.1 - 8.1e-68 228.1 15.1 9.2e-68 228.0 15.1 1.0 1 0 0 1 1 1 1 LrgB-like family LrgA PF03788.14 EHT98362.1 - 8.3 6.4 16.0 0.089 12.7 5.8 2.5 3 0 0 3 3 3 0 LrgA family YfaZ PF07437.11 EHT98363.1 - 3e-47 160.6 1.6 3.3e-47 160.4 1.6 1.0 1 0 0 1 1 1 1 YfaZ precursor OMP_b-brl PF13505.6 EHT98363.1 - 0.001 19.2 9.9 0.34 11.0 9.9 2.5 1 1 0 1 1 1 1 Outer membrane protein beta-barrel domain SSF PF00474.17 EHT98364.1 - 2.1e-132 441.9 40.4 3e-132 441.3 40.4 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family DUF2818 PF10993.8 EHT98364.1 - 0.004 17.7 0.1 0.004 17.7 0.1 4.0 5 0 0 5 5 5 1 Protein of unknown function (DUF2818) DUF2784 PF10861.8 EHT98364.1 - 3.3 7.8 12.3 0.27 11.3 4.5 3.1 3 0 0 3 3 3 0 Protein of Unknown function (DUF2784) DUF485 PF04341.12 EHT98365.1 - 4.4e-35 119.5 0.1 5e-35 119.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF485 MASE3 PF17159.4 EHT98365.1 - 0.015 14.9 0.4 0.018 14.6 0.4 1.0 1 0 0 1 1 1 0 Membrane-associated sensor domain DUF2157 PF09925.9 EHT98365.1 - 0.026 14.3 0.6 0.055 13.3 0.6 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) PNTB_4TM PF12769.7 EHT98365.1 - 0.056 13.9 0.7 0.067 13.7 0.7 1.1 1 0 0 1 1 1 0 4TM region of pyridine nucleotide transhydrogenase, mitoch DUF2207 PF09972.9 EHT98365.1 - 0.065 12.0 0.1 0.067 12.0 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) E1-E2_ATPase PF00122.20 EHT98365.1 - 0.13 11.8 0.1 0.16 11.5 0.1 1.1 1 0 0 1 1 1 0 E1-E2 ATPase AMP-binding PF00501.28 EHT98366.1 - 1.4e-94 317.1 0.0 1.7e-94 316.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EHT98366.1 - 6.5e-26 91.1 0.0 1.4e-25 90.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EHT98366.1 - 3.6e-21 74.8 0.2 9.1e-21 73.5 0.2 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus SDF PF00375.18 EHT98367.1 - 3.6e-118 395.0 35.7 4e-118 394.8 35.7 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF3806 PF12713.7 EHT98367.1 - 0.17 11.6 0.1 0.54 10.1 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3806) Tetraspanin PF00335.20 EHT98367.1 - 0.76 9.4 12.1 1.7 8.3 2.3 2.4 2 0 0 2 2 2 0 Tetraspanin family SIS_2 PF13580.6 EHT98368.1 - 1.1e-10 41.7 0.4 3.3e-10 40.1 0.4 1.9 1 1 0 1 1 1 1 SIS domain SIS PF01380.22 EHT98368.1 - 4.5e-09 36.3 0.9 1.4e-08 34.7 0.0 2.1 2 0 0 2 2 2 1 SIS domain Cas_Csy3 PF09615.10 EHT98368.1 - 0.13 11.5 0.1 0.2 10.9 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy3) PTS_EIIC PF02378.18 EHT98369.1 - 1.5e-32 112.9 25.7 1.5e-32 112.9 25.7 2.1 1 1 1 2 2 2 2 Phosphotransferase system, EIIC PTS_EIIB PF00367.20 EHT98369.1 - 8.7e-11 41.1 0.1 1.7e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 phosphotransferase system, EIIB DUF1471 PF07338.13 EHT98370.1 - 6.9e-10 38.7 3.3 9e-10 38.4 3.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1471) PepSY_2 PF13670.6 EHT98370.1 - 0.023 14.7 3.3 0.026 14.5 3.3 1.1 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain SbmA_BacA PF05992.12 EHT98371.1 - 4.4e-160 532.3 14.7 5.7e-160 531.9 14.7 1.1 1 0 0 1 1 1 1 SbmA/BacA-like family ABC_membrane_2 PF06472.15 EHT98371.1 - 2.3e-13 50.2 3.3 8.7e-13 48.3 3.3 1.9 1 1 0 1 1 1 1 ABC transporter transmembrane region 2 DUF1673 PF07895.11 EHT98371.1 - 5.8 6.6 9.5 0.25 11.0 2.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1673) Gluconate_2-dh3 PF13618.6 EHT98372.1 - 8.2e-39 132.9 0.1 1.2e-38 132.4 0.1 1.2 1 0 0 1 1 1 1 Gluconate 2-dehydrogenase subunit 3 Peptidase_C69 PF03577.15 EHT98372.1 - 0.19 10.6 0.0 0.26 10.1 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C69 GMC_oxred_C PF05199.13 EHT98373.1 - 3.4e-22 79.5 0.0 7.6e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EHT98373.1 - 1.2e-11 44.6 0.0 2.7e-10 40.1 0.0 2.4 2 1 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EHT98373.1 - 0.0026 17.9 0.7 0.077 13.2 0.0 3.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EHT98373.1 - 0.011 14.9 0.0 0.12 11.4 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 EHT98373.1 - 0.013 14.8 0.0 0.032 13.5 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 EHT98373.1 - 0.021 14.1 0.0 0.12 11.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EHT98373.1 - 0.037 13.1 0.0 0.058 12.4 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 EHT98373.1 - 0.09 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cytochrom_C PF00034.21 EHT98374.1 - 9e-24 84.4 0.0 2.5e-07 31.8 0.0 3.7 3 2 0 3 3 3 3 Cytochrome c Cytochrome_CBB3 PF13442.6 EHT98374.1 - 1.2e-21 76.8 0.4 2.3e-08 34.2 0.0 4.0 3 1 0 3 3 3 3 Cytochrome C oxidase, cbb3-type, subunit III Paired_CXXCH_1 PF09699.10 EHT98374.1 - 1.8e-06 27.5 2.0 0.33 10.8 0.0 3.4 3 0 0 3 3 3 3 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrome_C7 PF14522.6 EHT98374.1 - 0.00038 20.4 0.1 12 5.9 0.0 3.2 3 0 0 3 3 3 2 Cytochrome c7 and related cytochrome c DHOR PF06537.11 EHT98374.1 - 0.0029 16.3 0.1 0.3 9.7 0.0 2.7 3 0 0 3 3 3 2 Di-haem oxidoreductase, putative peroxidase Haem_bd PF14376.6 EHT98374.1 - 0.18 11.7 0.3 7.9 6.4 0.0 3.3 4 0 0 4 4 4 0 Haem-binding domain CCP_MauG PF03150.14 EHT98374.1 - 0.47 11.1 1.7 31 5.2 0.1 3.3 2 1 1 4 4 4 0 Di-haem cytochrome c peroxidase Sugar_tr PF00083.24 EHT98375.1 - 3.2e-34 118.6 28.6 1.1e-33 116.8 28.6 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EHT98375.1 - 5.5e-30 104.5 43.0 2.3e-22 79.4 20.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EHT98375.1 - 0.0016 17.9 8.1 0.0016 17.9 8.1 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 EHT98375.1 - 0.0064 15.1 31.3 0.076 11.6 4.0 3.7 1 1 1 3 3 3 3 MFS/sugar transport protein MCPsignal PF00015.21 EHT98377.1 - 1.9e-51 174.3 31.7 9.2e-51 172.1 20.0 2.4 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 EHT98377.1 - 4e-08 33.5 0.3 2.1e-06 28.0 0.0 3.5 3 1 0 3 3 3 1 HAMP domain Mod_r PF07200.13 EHT98377.1 - 0.015 15.4 1.7 0.015 15.4 1.7 2.1 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF4874 PF16173.5 EHT98377.1 - 0.071 12.8 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4874) I_LWEQ PF01608.17 EHT98377.1 - 0.078 13.2 19.8 0.54 10.5 12.1 2.6 1 1 1 2 2 2 0 I/LWEQ domain LOH1CR12 PF10158.9 EHT98377.1 - 1.5 8.9 4.6 7.5 6.6 0.0 2.8 1 1 2 3 3 3 0 Tumour suppressor protein WXG100 PF06013.12 EHT98377.1 - 1.8 8.9 13.3 1.6 9.0 0.3 4.0 4 1 0 4 4 4 0 Proteins of 100 residues with WXG DUF2203 PF09969.9 EHT98377.1 - 3.1 8.5 6.9 1.6 9.4 1.0 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DDE_Tnp_IS66 PF03050.14 EHT98378.1 - 1.1e-97 326.9 4.5 3.8e-97 325.1 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT98378.1 - 3.2e-16 59.3 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT98378.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT98378.1 - 8.7e-11 42.4 9.0 1.9e-10 41.4 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Phage_HK97_TLTM PF06120.11 EHT98378.1 - 0.011 15.0 0.8 0.021 14.0 0.8 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHT98378.1 - 0.02 15.2 4.2 0.084 13.2 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain UME PF08064.13 EHT98378.1 - 0.033 14.1 0.3 20 5.1 0.0 3.1 2 1 1 3 3 3 0 UME (NUC010) domain Exonuc_VII_L PF02601.15 EHT98378.1 - 0.039 13.5 2.7 0.04 13.5 1.0 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Troponin PF00992.20 EHT98378.1 - 0.044 14.1 2.8 0.078 13.3 2.8 1.3 1 0 0 1 1 1 0 Troponin FUSC PF04632.12 EHT98378.1 - 0.048 12.2 7.4 0.077 11.5 7.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tho2 PF11262.8 EHT98378.1 - 0.049 12.8 0.6 0.081 12.1 0.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FAM184 PF15665.5 EHT98378.1 - 0.052 13.3 8.0 0.082 12.7 8.0 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B HalX PF08663.10 EHT98378.1 - 0.13 12.6 2.4 0.34 11.3 2.4 1.7 1 0 0 1 1 1 0 HalX domain LXG PF04740.12 EHT98378.1 - 0.14 11.8 2.8 0.35 10.5 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHT98378.1 - 0.19 11.5 11.1 0.31 10.8 11.1 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DHR10 PF18595.1 EHT98378.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Zn-ribbon_8 PF09723.10 EHT98378.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF1192 PF06698.11 EHT98378.1 - 0.54 10.4 5.3 3.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHT98378.1 - 0.82 8.9 3.0 1.2 8.3 3.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHT98378.1 - 2 8.0 8.1 4.3 6.8 8.1 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHT98378.1 - 4.2 7.7 8.6 8.7 6.7 8.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CREPT PF16566.5 EHT98378.1 - 5.9 7.1 8.7 2.7 8.1 5.6 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour SlyX PF04102.12 EHT98378.1 - 9.3 7.0 9.0 18 6.1 2.3 3.0 1 1 1 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHT98379.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHT98380.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT98380.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT98380.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT98380.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix FeoB_N PF02421.18 EHT98381.1 - 3e-56 189.3 0.0 5.3e-56 188.5 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Gate PF07670.14 EHT98381.1 - 3.4e-50 169.0 9.1 1.6e-34 118.5 0.6 3.0 2 0 0 2 2 2 2 Nucleoside recognition FeoB_C PF07664.12 EHT98381.1 - 3.9e-22 77.7 0.4 3.9e-22 77.7 0.4 2.6 2 0 0 2 2 2 1 Ferrous iron transport protein B C terminus MMR_HSR1 PF01926.23 EHT98381.1 - 2e-17 63.3 0.0 3.6e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_Cyto PF17910.1 EHT98381.1 - 5.3e-10 39.7 0.0 1.5e-09 38.3 0.0 1.8 1 1 0 1 1 1 1 FeoB cytosolic helical domain SRPRB PF09439.10 EHT98381.1 - 2.5e-05 23.8 0.0 4.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EHT98381.1 - 0.017 15.0 0.1 3.8 7.4 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase GTP_EFTU PF00009.27 EHT98381.1 - 0.068 12.7 0.1 1.5 8.4 0.1 2.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EHT98381.1 - 0.071 13.2 0.0 11 6.0 0.0 2.2 2 0 0 2 2 2 0 Dynamin family FeoA PF04023.14 EHT98382.1 - 8e-08 32.4 0.0 8.8e-08 32.3 0.0 1.0 1 0 0 1 1 1 1 FeoA domain MCPsignal PF00015.21 EHT98383.1 - 3.5e-51 173.4 37.0 2e-50 171.0 22.9 3.1 3 0 0 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain TarH PF02203.15 EHT98383.1 - 2.5e-40 138.3 9.2 2.5e-40 138.3 9.2 3.6 4 1 0 4 4 4 1 Tar ligand binding domain homologue HAMP PF00672.25 EHT98383.1 - 9.9e-07 29.1 4.1 3.2e-05 24.2 0.4 3.8 3 1 0 3 3 3 1 HAMP domain ATP-synt_G PF04718.15 EHT98383.1 - 2.5 9.0 4.3 1.8 9.4 0.2 2.9 3 0 0 3 3 3 0 Mitochondrial ATP synthase g subunit Synaptobrevin PF00957.21 EHT98383.1 - 3.5 7.5 15.1 0.22 11.3 0.3 4.8 4 1 1 5 5 5 0 Synaptobrevin DUF1664 PF07889.12 EHT98383.1 - 8.7 6.4 16.1 1.1 9.3 0.9 4.5 4 1 0 4 4 4 0 Protein of unknown function (DUF1664) YCII PF03795.14 EHT98384.1 - 4.1e-08 33.5 0.0 5.3e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Flavodoxin_2 PF02525.17 EHT98385.1 - 3.4e-30 105.2 0.0 3.9e-30 105.1 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 EHT98385.1 - 7.4e-09 35.5 0.0 9.4e-09 35.2 0.0 1.3 1 1 0 1 1 1 1 NADPH-dependent FMN reductase DDE_3 PF13358.6 EHT98386.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHT98386.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHT98386.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHT98386.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHT98386.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHT98386.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHT98386.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHT98386.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 Abhydrolase_6 PF12697.7 EHT98387.1 - 4.3e-18 66.7 5.2 5.3e-18 66.4 5.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EHT98387.1 - 1e-09 38.0 2.8 4.7e-08 32.6 0.3 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 EHT98387.1 - 3.1e-08 33.6 0.0 4.1e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EHT98387.1 - 2.2e-07 30.8 1.0 0.0048 16.6 0.1 3.1 2 1 0 3 3 3 3 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 EHT98387.1 - 0.0054 16.6 1.4 0.0075 16.1 0.2 1.9 2 1 1 3 3 3 1 Serine hydrolase DUF4350 PF14258.6 EHT98387.1 - 0.012 16.0 0.1 0.078 13.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) HTH_18 PF12833.7 EHT98388.1 - 4.7e-23 81.3 0.1 8.7e-23 80.4 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain DJ-1_PfpI PF01965.24 EHT98388.1 - 3.2e-15 56.3 0.0 6.6e-15 55.3 0.0 1.5 2 0 0 2 2 2 1 DJ-1/PfpI family HTH_AraC PF00165.23 EHT98388.1 - 1.4e-13 50.6 0.0 2.6e-06 27.4 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_11 PF08279.12 EHT98388.1 - 0.00044 20.1 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 HTH domain HTH_24 PF13412.6 EHT98388.1 - 0.008 15.7 0.0 0.82 9.3 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Glyco_hydro_10 PF00331.20 EHT98389.1 - 6.4e-68 229.2 0.0 7.1e-68 229.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DUF3142 PF11340.8 EHT98389.1 - 0.075 12.9 0.2 0.15 11.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3142) Aldo_ket_red PF00248.21 EHT98390.1 - 2.9e-72 243.4 0.0 3.3e-72 243.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3860 PF12976.7 EHT98390.1 - 0.14 12.2 0.0 2 8.5 0.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3860) BMC PF00936.19 EHT98390.1 - 0.15 12.1 0.0 1.8 8.6 0.0 2.5 2 0 0 2 2 2 0 BMC domain OprB PF04966.12 EHT98391.1 - 6.2e-84 282.6 20.1 7.4e-84 282.3 20.1 1.1 1 0 0 1 1 1 1 Carbohydrate-selective porin, OprB family Cupin_2 PF07883.11 EHT98392.1 - 9.5e-06 25.2 0.5 1.3e-05 24.8 0.5 1.3 1 1 0 1 1 1 1 Cupin domain 3-HAO PF06052.12 EHT98392.1 - 0.00022 20.9 0.0 0.00027 20.6 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_3 PF05899.12 EHT98392.1 - 0.014 15.0 0.1 0.019 14.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_6 PF12852.7 EHT98392.1 - 0.043 13.5 0.0 0.045 13.5 0.0 1.1 1 0 0 1 1 1 0 Cupin AAA_18 PF13238.6 EHT98393.1 - 0.00019 22.0 0.0 0.0004 20.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain IPT PF01745.16 EHT98393.1 - 0.00031 20.2 0.0 0.00041 19.8 0.0 1.2 1 0 0 1 1 1 1 Isopentenyl transferase Cytidylate_kin PF02224.18 EHT98393.1 - 0.0018 18.1 0.0 0.003 17.3 0.0 1.4 1 1 0 1 1 1 1 Cytidylate kinase MMR_HSR1 PF01926.23 EHT98393.1 - 0.003 17.6 0.0 0.0072 16.4 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EHT98393.1 - 0.015 15.9 0.0 0.02 15.4 0.0 1.3 1 0 0 1 1 1 0 ABC transporter CobU PF02283.16 EHT98393.1 - 0.02 14.5 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_28 PF13521.6 EHT98393.1 - 0.028 14.7 0.0 0.043 14.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EHT98393.1 - 0.038 13.7 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EHT98393.1 - 0.039 13.7 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain SKI PF01202.22 EHT98393.1 - 0.044 13.9 0.0 0.065 13.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate kinase AAA_33 PF13671.6 EHT98393.1 - 0.05 13.8 0.0 0.097 12.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EHT98393.1 - 0.075 13.5 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EHT98393.1 - 0.11 12.3 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 EHT98393.1 - 0.24 11.8 0.0 0.36 11.3 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 EHT98393.1 - 0.24 11.4 0.0 0.37 10.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain Acetyltransf_4 PF13420.7 EHT98394.1 - 1.2e-17 64.4 0.0 1.4e-17 64.3 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EHT98394.1 - 1.4e-16 60.8 0.1 1.7e-16 60.5 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EHT98394.1 - 3.8e-10 40.1 0.0 5.7e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EHT98394.1 - 5e-10 40.2 0.0 6.4e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EHT98394.1 - 1.7e-06 28.0 0.0 2.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EHT98394.1 - 0.00026 21.1 0.0 0.00042 20.4 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF5556 PF17711.1 EHT98394.1 - 0.0019 18.1 0.0 0.0029 17.6 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5556) Acetyltransf_6 PF13480.7 EHT98394.1 - 0.046 13.9 0.2 0.071 13.3 0.2 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 EHT98394.1 - 0.05 13.6 0.0 0.092 12.7 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein IclR PF01614.18 EHT98395.1 - 8.2e-40 135.6 0.1 1.1e-39 135.2 0.1 1.2 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 EHT98395.1 - 4.2e-14 52.1 0.0 8.2e-14 51.1 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 EHT98395.1 - 8.4e-05 22.4 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 MarR family MarR PF01047.22 EHT98395.1 - 0.001 19.0 0.0 0.0023 17.8 0.0 1.6 1 0 0 1 1 1 1 MarR family DcpS_C PF11969.8 EHT98395.1 - 0.0041 17.6 0.0 0.01 16.3 0.0 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Rrf2 PF02082.20 EHT98395.1 - 0.012 16.0 0.1 0.04 14.2 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator TrmB PF01978.19 EHT98395.1 - 0.012 15.4 0.0 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 EHT98395.1 - 0.018 14.6 0.0 0.04 13.5 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Apo-CII PF05355.11 EHT98395.1 - 0.024 14.8 0.0 0.046 13.9 0.0 1.4 1 0 0 1 1 1 0 Apolipoprotein C-II Rio2_N PF09202.11 EHT98395.1 - 0.061 13.6 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Rio2, N-terminal HTH_36 PF13730.6 EHT98395.1 - 0.083 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 EHT98395.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Fe_dep_repress PF01325.19 EHT98395.1 - 0.15 12.2 0.2 0.49 10.6 0.0 1.9 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain ABC_tran PF00005.27 EHT98396.1 - 2.9e-51 173.6 0.0 9.9e-31 107.1 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EHT98396.1 - 2.2e-10 40.9 0.1 0.0051 16.7 0.0 3.1 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EHT98396.1 - 2.3e-07 30.5 0.0 0.03 13.8 0.0 3.2 1 1 2 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EHT98396.1 - 7.7e-05 22.4 0.4 0.0006 19.5 0.1 2.5 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 EHT98396.1 - 0.0015 18.3 0.2 0.0055 16.4 0.2 1.9 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EHT98396.1 - 0.0039 17.1 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EHT98396.1 - 0.015 15.6 0.0 0.037 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EHT98396.1 - 0.016 15.6 0.7 0.43 11.0 0.7 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EHT98396.1 - 0.021 15.3 0.0 0.034 14.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EHT98396.1 - 0.04 13.5 0.4 0.15 11.6 0.4 2.0 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EHT98396.1 - 0.042 13.9 0.1 0.15 12.2 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase TsaE PF02367.17 EHT98396.1 - 0.075 13.0 0.0 0.21 11.6 0.0 1.8 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EHT98396.1 - 0.14 12.0 0.1 0.72 9.8 0.1 2.0 2 0 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.17 EHT98396.1 - 0.17 11.6 0.7 22 4.7 0.1 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_13 PF13166.6 EHT98396.1 - 0.22 10.1 0.0 3.2 6.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain BPD_transp_2 PF02653.16 EHT98397.1 - 7.5e-30 104.0 35.6 7.5e-30 104.0 35.6 1.8 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component SPC25 PF06703.11 EHT98397.1 - 0.14 11.9 1.7 0.29 10.9 1.7 1.5 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Peripla_BP_4 PF13407.6 EHT98398.1 - 2.2e-26 93.0 3.2 2.8e-26 92.6 3.2 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 EHT98398.1 - 0.0023 17.4 0.1 0.0033 16.9 0.1 1.3 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family SGL PF08450.12 EHT98399.1 - 2.3e-48 164.9 0.0 2.8e-48 164.7 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 EHT98399.1 - 4.5e-05 23.3 1.2 5.1 7.3 0.2 4.1 3 1 0 3 3 3 3 NHL repeat Arylesterase PF01731.20 EHT98399.1 - 0.002 18.3 0.0 0.0059 16.8 0.0 1.7 2 0 0 2 2 2 1 Arylesterase Str_synth PF03088.16 EHT98399.1 - 0.0055 16.8 0.0 0.11 12.7 0.0 3.1 2 1 0 3 3 3 1 Strictosidine synthase Ldh_2 PF02615.14 EHT98400.1 - 7.8e-102 340.8 0.0 8.8e-102 340.7 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase DUF386 PF04074.12 EHT98401.1 - 1.1e-41 142.2 0.0 1.2e-41 142.1 0.0 1.0 1 0 0 1 1 1 1 YhcH/YjgK/YiaL MFS_1 PF07690.16 EHT98402.1 - 7.9e-61 205.9 68.0 2.6e-53 181.2 42.6 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EHT98402.1 - 0.00096 17.8 7.8 0.00096 17.8 7.8 2.8 2 1 2 4 4 4 1 MFS/sugar transport protein FGGY_N PF00370.21 EHT98403.1 - 2.4e-76 256.6 0.0 3.1e-76 256.2 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EHT98403.1 - 2.1e-25 89.6 0.2 6.3e-24 84.8 0.3 2.2 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 EHT98403.1 - 0.012 15.2 0.0 0.04 13.4 0.0 1.8 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family OMPdecase PF00215.24 EHT98404.1 - 1.8e-23 83.4 0.2 2.1e-23 83.1 0.2 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family QRPTase_C PF01729.19 EHT98404.1 - 4.2e-05 23.4 0.0 0.061 13.1 0.0 2.3 2 1 0 2 2 2 2 Quinolinate phosphoribosyl transferase, C-terminal domain GYD PF08734.11 EHT98404.1 - 0.078 12.9 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 GYD domain Ribul_P_3_epim PF00834.19 EHT98404.1 - 0.15 11.4 0.0 1.4 8.3 0.0 2.0 2 0 0 2 2 2 0 Ribulose-phosphate 3 epimerase family AP_endonuc_2 PF01261.24 EHT98405.1 - 8.7e-35 120.1 0.1 1.1e-34 119.7 0.1 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel PRMT5_TIM PF17285.2 EHT98405.1 - 0.0036 16.5 0.0 0.0049 16.1 0.0 1.1 1 0 0 1 1 1 1 PRMT5 TIM barrel domain Aldolase_II PF00596.21 EHT98406.1 - 4.4e-45 153.9 1.6 5.6e-45 153.6 1.6 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF1440 PF07274.12 EHT98407.1 - 2.4e-48 163.9 4.5 2.9e-48 163.6 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1440) Acyl_transf_3 PF01757.22 EHT98408.1 - 1.6e-32 113.0 39.1 1.9e-32 112.7 39.1 1.0 1 0 0 1 1 1 1 Acyltransferase family UspB PF10625.9 EHT98408.1 - 0.087 12.8 2.0 0.34 10.9 0.5 2.6 2 0 0 2 2 2 0 Universal stress protein B (UspB) TonB_dep_Rec PF00593.24 EHT98409.1 - 2.5e-28 100.2 54.9 2.5e-28 100.2 54.9 1.7 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 EHT98409.1 - 1.8e-18 67.1 1.0 4.5e-18 65.8 1.0 1.8 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain K_oxygenase PF13434.6 EHT98410.1 - 7.6e-112 373.8 0.0 9.5e-112 373.5 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EHT98410.1 - 3.3e-11 43.0 0.0 5e-09 35.8 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EHT98410.1 - 5.4e-05 21.8 0.0 0.0046 15.4 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EHT98410.1 - 0.00018 20.9 0.0 0.47 9.6 0.0 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase IucA_IucC PF04183.12 EHT98411.1 - 1.3e-68 231.1 0.1 2.2e-68 230.4 0.1 1.3 1 0 0 1 1 1 1 IucA / IucC family FhuF PF06276.12 EHT98411.1 - 1.4e-32 113.3 1.9 1.7e-32 113.1 0.4 1.9 2 0 0 2 2 2 1 Ferric iron reductase FhuF-like transporter Acetyltransf_8 PF13523.6 EHT98412.1 - 1e-51 174.4 0.4 2.1e-51 173.4 0.3 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EHT98412.1 - 0.0006 20.5 0.0 0.0011 19.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain IucA_IucC PF04183.12 EHT98413.1 - 1.2e-52 178.9 2.1 2.1e-52 178.1 2.1 1.4 1 0 0 1 1 1 1 IucA / IucC family FhuF PF06276.12 EHT98413.1 - 3.2e-28 99.2 1.3 3.2e-28 99.2 1.3 2.4 3 0 0 3 3 3 1 Ferric iron reductase FhuF-like transporter MFS_1 PF07690.16 EHT98414.1 - 6.6e-16 58.2 64.6 1.3e-13 50.7 25.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily YrhK PF14145.6 EHT98414.1 - 4.8 7.1 9.2 3.2 7.7 2.0 2.9 2 1 0 2 2 2 0 YrhK-like protein MFS_2 PF13347.6 EHT98414.1 - 6.9 5.1 31.6 0.55 8.7 10.4 3.0 2 1 1 3 3 3 0 MFS/sugar transport protein FAD_binding_9 PF08021.11 EHT98415.1 - 3.7e-37 127.2 0.0 5.6e-37 126.6 0.0 1.3 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain SIP PF04954.13 EHT98415.1 - 1.1e-34 119.5 0.4 2.4e-34 118.4 0.4 1.6 1 0 0 1 1 1 1 Siderophore-interacting protein GFA PF04828.14 EHT98416.1 - 0.00022 21.5 0.0 0.00028 21.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme LysR_substrate PF03466.20 EHT98417.1 - 0.0072 15.7 0.1 0.0074 15.7 0.1 1.0 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EHT98418.1 - 1.3e-14 53.8 0.0 2.7e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 EHT98418.1 - 9.4e-13 48.0 0.5 1.6e-12 47.3 0.5 1.3 1 0 0 1 1 1 1 LysR substrate binding domain PA_decarbox PF05870.11 EHT98419.1 - 9.8e-84 278.7 0.5 1.1e-83 278.6 0.5 1.0 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) MoaF PF10703.9 EHT98419.1 - 0.00033 20.5 0.1 0.00048 20.0 0.1 1.2 1 0 0 1 1 1 1 MoaF N-terminal domain DDE_Tnp_1 PF01609.21 EHT98420.1 - 7.3e-16 58.5 0.3 1.4e-15 57.5 0.3 1.4 1 1 0 1 1 1 1 Transposase DDE domain Sulf_transp PF04143.14 EHT98421.1 - 2.3e-08 34.0 6.1 2.3e-08 34.0 6.1 2.1 2 0 0 2 2 2 1 Sulphur transport Sulf_transp PF04143.14 EHT98422.1 - 0.00064 19.4 12.2 0.00064 19.4 12.2 2.6 1 1 0 2 2 2 1 Sulphur transport LapA_dom PF06305.11 EHT98422.1 - 0.47 10.3 0.2 0.47 10.3 0.2 3.4 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain Phage_holin_3_6 PF07332.11 EHT98422.1 - 0.99 9.5 16.1 0.94 9.5 3.1 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III LacI PF00356.21 EHT98423.1 - 4e-18 64.9 0.1 9.5e-18 63.7 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_3 PF13377.6 EHT98423.1 - 2.9e-17 63.5 0.2 1e-15 58.5 0.0 2.2 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 EHT98423.1 - 5e-14 52.4 0.0 7.8e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 EHT98423.1 - 3.2e-10 40.0 0.0 4.1e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain HTH_31 PF13560.6 EHT98423.1 - 0.021 15.2 1.0 0.35 11.2 0.2 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain TetR_N PF00440.23 EHT98423.1 - 0.076 12.8 0.6 0.21 11.4 0.6 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family HTH_10 PF04967.12 EHT98423.1 - 0.082 12.7 0.1 0.2 11.5 0.1 1.6 1 0 0 1 1 1 0 HTH DNA binding domain HHH PF00633.23 EHT98423.1 - 0.15 12.0 0.1 0.37 10.7 0.1 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Glyco_hydro_32N PF00251.20 EHT98424.1 - 9.3e-93 311.1 0.0 1.1e-92 310.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 EHT98424.1 - 9.8e-11 41.9 0.0 1.8e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_43 PF04616.14 EHT98424.1 - 0.0044 16.4 0.1 0.66 9.2 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 PTS_EIIC PF02378.18 EHT98425.1 - 4.1e-49 167.4 38.5 4.1e-49 167.4 38.5 1.9 1 1 1 2 2 2 1 Phosphotransferase system, EIIC PTS_EIIB PF00367.20 EHT98425.1 - 2.4e-12 46.1 0.1 4.6e-12 45.2 0.1 1.4 1 0 0 1 1 1 1 phosphotransferase system, EIIB LamB PF02264.15 EHT98426.1 - 9.8e-105 351.5 9.6 1.5e-104 351.0 9.6 1.2 1 0 0 1 1 1 1 LamB porin Sugarporin_N PF11471.8 EHT98426.1 - 3.3e-18 65.4 6.8 3.3e-18 65.4 6.8 2.9 1 1 2 3 3 3 1 Maltoporin periplasmic N-terminal extension Tropomyosin PF00261.20 EHT98426.1 - 0.0017 17.8 6.8 0.0027 17.1 6.8 1.2 1 0 0 1 1 1 1 Tropomyosin SKA1 PF07160.12 EHT98426.1 - 0.045 13.6 0.3 0.07 13.0 0.3 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 XhlA PF10779.9 EHT98426.1 - 0.052 13.8 2.9 0.077 13.2 0.8 2.2 1 1 1 2 2 2 0 Haemolysin XhlA Fmp27_WPPW PF10359.9 EHT98426.1 - 0.091 11.6 0.3 0.12 11.1 0.3 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4407 PF14362.6 EHT98426.1 - 0.1 12.0 5.6 0.18 11.1 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CCDC53 PF10152.9 EHT98426.1 - 0.44 11.0 6.6 0.73 10.2 6.6 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Uso1_p115_C PF04871.13 EHT98426.1 - 0.68 10.3 12.6 1.3 9.4 12.6 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4200 PF13863.6 EHT98426.1 - 1.2 9.6 10.9 2 8.8 10.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) ERM PF00769.19 EHT98426.1 - 1.5 8.5 16.4 2.5 7.9 16.4 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family GrpE PF01025.19 EHT98426.1 - 6.1 6.5 8.3 11 5.7 8.3 1.3 1 0 0 1 1 1 0 GrpE LacY_symp PF01306.19 EHT98427.1 - 2.4e-207 688.6 38.9 2.8e-207 688.4 38.9 1.0 1 0 0 1 1 1 1 LacY proton/sugar symporter MFS_1 PF07690.16 EHT98427.1 - 7.9e-22 77.6 51.5 5.5e-20 71.6 40.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EHT98427.1 - 3.6e-20 72.2 38.8 1.7e-19 69.9 38.8 1.8 1 1 0 1 1 1 1 MFS_1 like family DUF5432 PF17497.2 EHT98427.1 - 0.37 10.9 5.8 0.41 10.8 3.5 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5432) Glyco_hydro_2_C PF02836.17 EHT98428.1 - 1e-117 392.6 0.0 1.6e-117 392.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 EHT98428.1 - 7.5e-67 224.5 0.3 1.5e-66 223.5 0.3 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Bgal_small_N PF02929.17 EHT98428.1 - 1.7e-60 204.7 0.3 4.2e-60 203.4 0.1 1.7 2 0 0 2 2 2 1 Beta galactosidase small chain DUF4981 PF16353.5 EHT98428.1 - 4.5e-19 68.7 0.1 1.6e-18 67.0 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 EHT98428.1 - 3.6e-16 59.8 0.0 8.1e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 PfkB PF00294.24 EHT98429.1 - 3.8e-66 223.4 0.0 4.3e-66 223.3 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase GST_C_2 PF13410.6 EHT98430.1 - 8.7e-10 38.5 0.1 2e-09 37.3 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EHT98430.1 - 1.1e-09 38.4 0.1 1.9e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EHT98430.1 - 5.9e-06 26.5 0.0 2.2e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EHT98430.1 - 6.3e-06 26.3 0.1 1.1e-05 25.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EHT98430.1 - 0.00024 21.3 0.0 0.00079 19.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EHT98430.1 - 0.0017 18.7 0.0 0.0042 17.5 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 EHT98430.1 - 0.056 13.2 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Cyc-maltodext_C PF10438.9 EHT98430.1 - 0.09 12.9 0.0 0.2 11.8 0.0 1.6 1 1 0 1 1 1 0 Cyclo-malto-dextrinase C-terminal domain Cuticle_2 PF08184.11 EHT98430.1 - 0.11 12.5 2.2 0.28 11.2 2.2 1.6 1 0 0 1 1 1 0 Cuticle protein 7 isoform family DUF1330 PF07045.11 EHT98431.1 - 1.5e-24 86.2 0.1 1.6e-24 86.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1330) YCII PF03795.14 EHT98431.1 - 0.0059 17.0 0.0 0.0076 16.6 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain EthD PF07110.11 EHT98431.1 - 0.096 13.9 0.1 0.14 13.3 0.1 1.5 1 1 0 1 1 1 0 EthD domain MCPsignal PF00015.21 EHT98432.1 - 9.6e-39 132.9 18.6 9.6e-39 132.9 18.6 2.7 2 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 EHT98432.1 - 0.00014 22.0 18.7 0.0011 19.1 0.5 4.3 2 2 2 4 4 4 3 Bacterial protein of unknown function (DUF948) SPC12 PF06645.13 EHT98432.1 - 0.29 11.3 3.4 1.3 9.2 3.4 2.1 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) IFT46_B_C PF12317.8 EHT98432.1 - 1.5 8.5 5.2 0.39 10.4 2.0 1.6 2 0 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Vps53_N PF04100.12 EHT98432.1 - 1.7 7.6 14.4 0.08 11.9 4.9 2.2 2 0 0 2 2 2 0 Vps53-like, N-terminal Lipoprotein_7 PF01540.16 EHT98432.1 - 3 7.1 7.1 22 4.2 7.1 2.0 1 1 0 1 1 1 0 Adhesin lipoprotein Syntaxin-6_N PF09177.11 EHT98432.1 - 5.8 7.5 10.8 4.7 7.8 4.7 2.9 2 1 0 2 2 2 0 Syntaxin 6, N-terminal GAS PF13851.6 EHT98432.1 - 6.3 6.1 14.7 3.4 7.0 7.0 2.5 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF932 PF06067.11 EHT98432.1 - 8.5 6.1 13.8 2.2 8.0 2.4 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF932) YabA PF06156.13 EHT98432.1 - 9.7 6.9 11.4 6.7 7.4 0.6 3.1 2 2 2 4 4 4 0 Initiation control protein YabA LysR_substrate PF03466.20 EHT98433.1 - 8.2e-43 146.2 2.8 1.4e-42 145.5 2.8 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EHT98433.1 - 5.8e-18 64.6 2.9 5.8e-18 64.6 2.9 1.9 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 EHT98433.1 - 0.0012 18.6 1.5 0.003 17.3 1.5 1.6 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_24 PF13412.6 EHT98433.1 - 0.015 14.9 0.3 0.037 13.6 0.3 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Matrilin_ccoil PF10393.9 EHT98433.1 - 0.021 14.7 0.2 0.057 13.3 0.2 1.7 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin HTH_28 PF13518.6 EHT98433.1 - 0.089 12.9 0.7 0.29 11.3 0.2 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain Iso_dh PF00180.20 EHT98434.1 - 1.3e-88 297.5 0.0 1.5e-88 297.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Glyco_hydro_28 PF00295.17 EHT98435.1 - 2.7e-25 89.1 0.0 3.7e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 EHT98435.1 - 3.9e-06 26.8 0.0 0.00016 21.6 0.0 2.2 1 1 0 1 1 1 1 Right handed beta helix region Pectate_lyase_3 PF12708.7 EHT98435.1 - 0.0017 18.3 0.0 0.2 11.5 0.0 2.3 2 0 0 2 2 2 2 Pectate lyase superfamily protein BPD_transp_1 PF00528.22 EHT98436.1 - 8.1e-24 84.4 19.9 8.1e-24 84.4 19.9 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF2427 PF10348.9 EHT98436.1 - 0.071 12.9 0.1 0.071 12.9 0.1 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF2427) BPD_transp_1 PF00528.22 EHT98437.1 - 4.8e-16 59.0 11.8 4.8e-16 59.0 11.8 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component 3-alpha PF03475.14 EHT98437.1 - 0.045 13.6 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 3-alpha domain Acetyltransf_1 PF00583.25 EHT98438.1 - 3.1e-06 27.4 0.0 1.2e-05 25.5 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EHT98438.1 - 3.7e-05 24.1 0.0 0.0022 18.4 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EHT98438.1 - 0.0041 17.1 0.0 0.015 15.3 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EHT98438.1 - 0.018 15.0 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein ROK PF00480.20 EHT98439.1 - 6.8e-37 127.5 0.0 9.2e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 ROK family HTH_24 PF13412.6 EHT98439.1 - 2e-06 27.3 0.7 7.2e-06 25.5 0.1 2.2 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 EHT98439.1 - 8.2e-06 25.6 2.1 3.6e-05 23.6 0.3 2.5 2 0 0 2 2 2 1 MarR family MarR PF01047.22 EHT98439.1 - 1.2e-05 25.1 0.1 3.9e-05 23.5 0.1 1.9 2 0 0 2 2 2 1 MarR family HTH_IclR PF09339.10 EHT98439.1 - 0.00066 19.4 4.1 0.0063 16.3 0.2 3.3 3 0 0 3 3 3 1 IclR helix-turn-helix domain HTH_Crp_2 PF13545.6 EHT98439.1 - 0.018 15.0 0.3 0.065 13.2 0.3 2.0 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain TrmB PF01978.19 EHT98439.1 - 0.028 14.3 0.0 0.068 13.1 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.7 EHT98439.1 - 0.3 11.2 2.0 3.2 7.9 0.1 2.9 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 EHT98439.1 - 0.33 10.8 3.4 0.26 11.1 0.4 2.4 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain BcrAD_BadFG PF01869.20 EHT98440.1 - 1.3e-32 113.4 0.3 1.4e-32 113.3 0.3 1.0 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family FGGY_N PF00370.21 EHT98440.1 - 0.076 12.6 0.0 0.23 11.0 0.0 1.8 1 1 1 2 2 2 0 FGGY family of carbohydrate kinases, N-terminal domain GFO_IDH_MocA PF01408.22 EHT98441.1 - 1.5e-17 64.5 0.0 9.3e-17 62.0 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EHT98441.1 - 1.9e-05 24.6 0.0 9.3e-05 22.4 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain MFS_1 PF07690.16 EHT98443.1 - 2e-52 178.3 57.4 1.5e-30 106.3 33.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EHT98443.1 - 7.1e-18 64.6 22.4 9e-12 44.5 12.8 2.9 1 1 2 3 3 3 2 MFS_1 like family Sugar_tr PF00083.24 EHT98443.1 - 8.1e-13 48.0 33.0 3.1e-06 26.3 5.9 3.9 1 1 1 3 3 3 3 Sugar (and other) transporter MFS_3 PF05977.13 EHT98443.1 - 4.1e-05 22.2 27.4 8.5e-05 21.1 6.5 2.1 1 1 1 2 2 2 2 Transmembrane secretion effector MFS_4 PF06779.14 EHT98443.1 - 0.0041 16.5 4.8 0.0041 16.5 4.8 3.2 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB B12D PF06522.11 EHT98443.1 - 5.8 6.8 5.7 84 3.1 0.0 3.9 4 0 0 4 4 4 0 NADH-ubiquinone reductase complex 1 MLRQ subunit LysR_substrate PF03466.20 EHT98444.1 - 2.8e-33 115.1 5.7 3.7e-33 114.7 5.7 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EHT98444.1 - 2.4e-18 65.8 1.4 4e-18 65.1 1.4 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Sigma70_r4 PF04545.16 EHT98444.1 - 0.011 15.2 0.5 0.087 12.4 0.1 2.2 1 1 1 2 2 2 0 Sigma-70, region 4 HTH_28 PF13518.6 EHT98444.1 - 0.05 13.7 0.1 0.13 12.4 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 EHT98444.1 - 0.066 13.0 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_18 PF12833.7 EHT98445.1 - 4.9e-21 74.8 3.1 6.7e-21 74.3 3.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 EHT98445.1 - 6.1e-19 67.6 0.3 4.4e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Response_reg PF00072.24 EHT98446.1 - 2.2e-24 85.8 0.0 3.2e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 EHT98446.1 - 1.1e-18 67.1 0.1 2.3e-18 66.0 0.1 1.6 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal DNA_meth_N PF18284.1 EHT98446.1 - 0.073 13.0 0.5 0.54 10.2 0.1 2.5 3 0 0 3 3 3 0 DNA methylase N-terminal domain FleQ PF06490.11 EHT98446.1 - 0.13 12.6 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ HATPase_c PF02518.26 EHT98447.1 - 2e-14 54.0 0.0 3.8e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EHT98447.1 - 1.3e-11 44.3 0.4 3.9e-11 42.8 0.4 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 EHT98447.1 - 0.00097 19.5 0.1 0.0044 17.4 0.0 2.2 2 0 0 2 2 2 1 HAMP domain KfrA_N PF11740.8 EHT98447.1 - 0.026 15.2 2.0 0.22 12.2 1.8 2.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term HATPase_c_2 PF13581.6 EHT98447.1 - 0.03 14.3 0.0 0.066 13.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 EHT98447.1 - 0.04 13.8 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 GHKL domain TatC PF00902.18 EHT98447.1 - 0.089 12.6 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 Sec-independent protein translocase protein (TatC) XLF PF09302.11 EHT98447.1 - 0.16 12.1 0.7 0.28 11.3 0.7 1.4 1 0 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Acyl_transf_3 PF01757.22 EHT98447.1 - 0.56 9.2 4.3 0.17 10.9 1.0 1.6 2 0 0 2 2 2 0 Acyltransferase family Channel_Tsx PF03502.13 EHT98448.1 - 4.4e-78 262.4 19.0 5e-78 262.2 19.0 1.0 1 0 0 1 1 1 1 Nucleoside-specific channel-forming protein, Tsx NmrA PF05368.13 EHT98450.1 - 8.5e-05 22.2 0.0 9.4e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family SGL PF08450.12 EHT98451.1 - 1e-59 202.1 0.0 1.2e-59 201.8 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region DUF5122 PF17164.4 EHT98451.1 - 0.0067 16.7 0.1 0.024 14.9 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5122) beta-propeller DMT_YdcZ PF04657.13 EHT98452.1 - 2.2e-31 109.0 17.7 2.5e-31 108.8 17.7 1.0 1 0 0 1 1 1 1 Putative inner membrane exporter, YdcZ Amidohydro_1 PF01979.20 EHT98453.1 - 1.9e-29 103.1 0.2 6.4e-23 81.6 0.0 2.5 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_3 PF07969.11 EHT98453.1 - 2.7e-14 53.5 0.4 4.3e-08 33.1 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family LysR_substrate PF03466.20 EHT98454.1 - 1.8e-42 145.1 0.1 2.5e-42 144.6 0.1 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EHT98454.1 - 4.5e-18 64.9 0.4 8.7e-18 64.0 0.4 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HemN_C PF06969.16 EHT98454.1 - 0.13 12.4 0.0 0.65 10.1 0.0 2.1 2 0 0 2 2 2 0 HemN C-terminal domain DUF1652 PF07865.11 EHT98454.1 - 0.18 11.7 0.4 0.48 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1652) DDE_Tnp_IS66 PF03050.14 EHT98455.1 - 2.2e-98 329.2 3.2 1.6e-97 326.4 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT98455.1 - 3.2e-16 59.3 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT98455.1 - 8e-15 55.0 1.3 1.9e-14 53.8 1.3 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT98455.1 - 1.7e-11 44.7 9.6 3.5e-11 43.7 9.6 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHT98455.1 - 0.017 14.9 6.4 0.027 14.3 6.4 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Phage_HK97_TLTM PF06120.11 EHT98455.1 - 0.022 14.0 1.7 0.042 13.0 1.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHT98455.1 - 0.022 15.1 4.3 0.091 13.1 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Exonuc_VII_L PF02601.15 EHT98455.1 - 0.029 14.0 1.8 0.039 13.5 0.6 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit FUSC PF04632.12 EHT98455.1 - 0.036 12.6 6.9 0.056 12.0 6.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tho2 PF11262.8 EHT98455.1 - 0.057 12.6 0.5 0.094 11.9 0.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Troponin PF00992.20 EHT98455.1 - 0.062 13.6 3.0 0.11 12.8 3.0 1.3 1 0 0 1 1 1 0 Troponin LXG PF04740.12 EHT98455.1 - 0.11 12.2 2.6 0.33 10.6 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHT98455.1 - 0.16 11.8 10.8 0.26 11.1 10.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family UME PF08064.13 EHT98455.1 - 0.16 11.9 0.5 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain HalX PF08663.10 EHT98455.1 - 0.23 11.8 3.1 0.59 10.5 3.1 1.7 1 0 0 1 1 1 0 HalX domain DHR10 PF18595.1 EHT98455.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF1192 PF06698.11 EHT98455.1 - 0.48 10.5 5.3 3.4 7.8 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHT98455.1 - 1.1 8.4 3.1 1.7 7.8 3.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHT98455.1 - 2.8 7.4 7.9 6.1 6.3 7.9 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHT98455.1 - 3.3 8.1 7.9 6.7 7.0 7.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 EHT98455.1 - 7.2 7.3 8.7 7.7 7.2 1.0 3.0 1 1 1 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHT98456.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHT98457.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT98457.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT98457.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT98457.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix HTH_1 PF00126.27 EHT98458.1 - 4.5e-18 64.9 0.2 7.8e-18 64.2 0.2 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 EHT98458.1 - 1.3e-14 54.1 0.0 2.1e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 LysR substrate binding domain MarR_2 PF12802.7 EHT98458.1 - 0.0082 16.0 0.1 0.024 14.5 0.1 1.8 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 EHT98458.1 - 0.062 12.9 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HU-CCDC81_euk_2 PF18289.1 EHT98458.1 - 0.15 12.2 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 Aldo_ket_red PF00248.21 EHT98459.1 - 1.9e-69 234.1 0.0 2.3e-69 233.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ESCRT-II PF05871.12 EHT98459.1 - 0.046 14.0 0.0 0.12 12.6 0.0 1.6 2 0 0 2 2 2 0 ESCRT-II complex subunit Flavodoxin_2 PF02525.17 EHT98460.1 - 5.2e-35 121.0 0.0 5.6e-35 120.9 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 EHT98460.1 - 0.0036 17.0 0.0 0.0044 16.8 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase DDE_Tnp_1_5 PF13737.6 EHT98461.1 - 1.2e-44 151.2 0.0 3.1e-44 149.9 0.0 1.7 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 EHT98461.1 - 1.9e-24 86.5 1.0 2.3e-24 86.2 1.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain Phage_integrase PF00589.22 EHT98462.1 - 1.7e-19 70.3 0.2 2.3e-19 69.8 0.2 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_5 PF13102.6 EHT98462.1 - 6.7e-08 32.8 0.1 1.5e-07 31.7 0.1 1.6 1 0 0 1 1 1 1 Phage integrase SAM-like domain Phage_int_SAM_1 PF02899.17 EHT98462.1 - 7.2e-07 29.4 0.0 3.4e-06 27.3 0.0 2.2 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 EHT98462.1 - 0.00011 22.6 0.1 0.00047 20.6 0.0 2.0 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Josephin PF02099.17 EHT98463.1 - 0.11 12.5 0.7 0.17 12.0 0.7 1.4 1 0 0 1 1 1 0 Josephin DsbC PF11412.8 EHT98464.1 - 3.6e-33 114.2 0.0 5.5e-33 113.6 0.0 1.3 1 0 0 1 1 1 1 Disulphide bond corrector protein DsbC DsbD PF02683.15 EHT98464.1 - 3.7e-20 72.7 17.9 6e-20 72.1 17.9 1.3 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region Thioredoxin_7 PF13899.6 EHT98464.1 - 8.7e-09 35.4 0.1 1.6e-08 34.6 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EHT98464.1 - 2.3e-08 34.5 0.0 4.4e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.20 EHT98464.1 - 5e-07 29.7 0.0 7.9e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DsbD_2 PF13386.6 EHT98464.1 - 6.2e-07 29.6 24.9 6.2e-07 29.6 24.9 2.1 2 1 0 2 2 2 1 Cytochrome C biogenesis protein transmembrane region PRP8_domainIV PF12134.8 EHT98464.1 - 0.071 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 PRP8 domain IV core CutA1 PF03091.15 EHT98465.1 - 1.8e-32 111.1 0.0 2e-32 111.0 0.0 1.0 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein ERAP1_C PF11838.8 EHT98465.1 - 0.06 12.9 0.1 0.068 12.7 0.1 1.1 1 0 0 1 1 1 0 ERAP1-like C-terminal domain DUF508 PF04370.12 EHT98465.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF508) DcuA_DcuB PF03605.14 EHT98466.1 - 6.6e-146 485.9 26.3 8e-146 485.7 26.3 1.1 1 0 0 1 1 1 1 Anaerobic c4-dicarboxylate membrane transporter Lyase_1 PF00206.20 EHT98467.1 - 1.2e-106 356.7 0.0 1.4e-106 356.4 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 EHT98467.1 - 1.3e-17 63.9 0.0 3.9e-17 62.4 0.0 1.9 1 0 0 1 1 1 1 Fumarase C C-terminus FxsA PF04186.13 EHT98468.1 - 2.3e-32 111.4 6.9 3e-32 111.0 6.9 1.1 1 0 0 1 1 1 1 FxsA cytoplasmic membrane protein MMM1 PF10296.9 EHT98468.1 - 0.13 11.3 0.1 0.17 10.9 0.1 1.1 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 Cpn10 PF00166.21 EHT98469.1 - 6.7e-30 103.0 1.7 7.4e-30 102.9 1.7 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cpn60_TCP1 PF00118.24 EHT98470.1 - 3.8e-95 319.4 19.4 6e-95 318.7 19.4 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family REF PF05755.12 EHT98470.1 - 0.061 13.1 0.3 0.16 11.8 0.3 1.7 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) DUF4156 PF13698.6 EHT98471.1 - 3.2e-31 107.5 0.1 3.7e-31 107.3 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4156) Radical_SAM PF04055.21 EHT98472.1 - 6.6e-09 36.4 0.0 4.2e-08 33.7 0.0 2.0 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EHT98472.1 - 7.1e-07 29.6 0.0 1.5e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EHT98472.1 - 5.6e-06 26.5 0.0 9.6e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Elong-fact-P_C PF09285.11 EHT98473.1 - 3.2e-25 87.6 0.3 8.1e-25 86.3 0.3 1.8 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP_N PF08207.12 EHT98473.1 - 3.5e-24 84.6 0.0 8.1e-24 83.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain EFP PF01132.20 EHT98473.1 - 2e-21 75.7 2.3 3.9e-21 74.8 2.3 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain Entericidin PF08085.11 EHT98474.1 - 1.2e-08 34.7 0.0 1.6e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Entericidin EcnA/B family Entericidin PF08085.11 EHT98475.1 - 8.8e-09 35.1 2.5 1.1e-08 34.8 2.5 1.1 1 0 0 1 1 1 1 Entericidin EcnA/B family LPAM_1 PF08139.12 EHT98475.1 - 0.0039 17.6 3.9 0.08 13.5 0.3 2.1 1 1 1 2 2 2 2 Prokaryotic membrane lipoprotein lipid attachment site MLTD_N PF06474.12 EHT98475.1 - 0.0067 16.6 0.4 0.0067 16.6 0.4 1.6 2 0 0 2 2 2 1 MltD lipid attachment motif Lipocalin_2 PF08212.12 EHT98476.1 - 5.5e-44 149.6 0.1 6.4e-44 149.4 0.1 1.0 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 EHT98476.1 - 1.3e-10 41.6 0.0 1.6e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family VDE PF07137.11 EHT98476.1 - 0.055 13.0 0.0 0.17 11.4 0.0 1.7 1 1 0 1 1 1 0 VDE lipocalin domain tRNA-synt_2 PF00152.20 EHT98477.1 - 2.3e-47 161.6 0.0 3e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 EHT98477.1 - 0.016 14.7 0.0 0.21 11.0 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Trypsin_2 PF13365.6 EHT98478.1 - 5e-29 102.1 0.2 9e-29 101.3 0.2 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 EHT98478.1 - 1.1e-18 67.8 0.3 2.5e-18 66.7 0.3 1.5 1 1 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 EHT98478.1 - 8.9e-16 58.0 0.8 2.6e-15 56.5 0.2 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EHT98478.1 - 3.1e-11 43.0 0.6 3.1e-11 43.0 0.6 1.8 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EHT98478.1 - 3.5e-11 43.3 0.6 3.5e-11 43.3 0.6 2.5 3 0 0 3 3 3 1 PDZ domain Peptidase_S46 PF10459.9 EHT98478.1 - 0.17 10.5 2.9 0.49 9.0 0.9 2.1 2 0 0 2 2 2 0 Peptidase S46 Trypsin_2 PF13365.6 EHT98479.1 - 2.9e-30 106.1 0.6 4.8e-30 105.4 0.6 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ PF00595.24 EHT98479.1 - 2.7e-29 101.3 7.3 2.2e-16 60.0 0.2 3.2 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 EHT98479.1 - 1.2e-24 86.4 5.3 2.1e-16 60.0 0.1 2.8 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 EHT98479.1 - 1.1e-19 70.0 1.2 5.4e-10 39.0 0.0 2.7 2 0 0 2 2 2 2 PDZ domain Trypsin PF00089.26 EHT98479.1 - 8.1e-17 61.8 0.1 1.5e-16 60.9 0.1 1.4 1 0 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.6 EHT98479.1 - 0.0025 17.7 1.0 0.24 11.4 0.1 2.9 2 0 0 2 2 2 1 Tricorn protease PDZ domain PDZ_1 PF12812.7 EHT98479.1 - 0.005 16.8 0.1 0.18 11.9 0.0 2.6 2 1 0 2 2 2 1 PDZ-like domain DUF3394 PF11874.8 EHT98479.1 - 0.008 15.9 1.1 0.15 11.7 0.2 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF3394) Peptidase_S46 PF10459.9 EHT98479.1 - 0.024 13.3 0.6 0.34 9.5 0.7 2.0 2 0 0 2 2 2 0 Peptidase S46 DUF1043 PF06295.12 EHT98480.1 - 3.6e-45 153.0 0.0 4e-45 152.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1043) HemX PF04375.14 EHT98480.1 - 0.00082 18.7 0.0 0.0011 18.3 0.0 1.1 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase LXG PF04740.12 EHT98480.1 - 0.0067 16.2 0.9 0.0088 15.8 0.9 1.1 1 0 0 1 1 1 1 LXG domain of WXG superfamily Apolipoprotein PF01442.18 EHT98480.1 - 0.024 14.5 1.3 0.032 14.1 1.3 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain PCYCGC PF13798.6 EHT98480.1 - 0.077 12.8 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function with PCYCGC motif MctB PF11382.8 EHT98480.1 - 0.084 12.6 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB DUF3496 PF12001.8 EHT98480.1 - 0.15 12.4 0.7 0.49 10.8 0.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3496) KAP PF05804.12 EHT98480.1 - 0.18 9.9 0.0 0.21 9.7 0.0 1.0 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) AFG1_ATPase PF03969.16 EHT98481.1 - 7.6e-150 498.8 0.1 8.9e-150 498.6 0.1 1.0 1 0 0 1 1 1 1 AFG1-like ATPase Ribosomal_L13 PF00572.18 EHT98482.1 - 7.4e-57 191.0 0.3 8.5e-57 190.8 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 IMS_C PF11799.8 EHT98482.1 - 0.066 13.9 0.0 0.085 13.6 0.0 1.2 1 0 0 1 1 1 0 impB/mucB/samB family C-terminal domain DUF3659 PF12396.8 EHT98482.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) Ribosomal_S9 PF00380.19 EHT98483.1 - 1.6e-46 157.7 0.7 1.8e-46 157.6 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Flg_hook PF02120.16 EHT98483.1 - 0.062 13.2 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK GST_N PF02798.20 EHT98484.1 - 8.2e-20 70.9 0.0 8e-18 64.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EHT98484.1 - 3e-16 59.6 0.0 1e-15 57.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EHT98484.1 - 7.3e-13 48.6 0.1 1.6e-12 47.5 0.1 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EHT98484.1 - 7e-12 45.4 0.0 1e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EHT98484.1 - 9.2e-08 32.0 0.0 1.6e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 EHT98484.1 - 0.00018 21.6 0.0 0.00042 20.5 0.0 1.6 2 0 0 2 2 2 1 Glutaredoxin GST_C_5 PF16865.5 EHT98484.1 - 0.05 14.2 0.0 0.28 11.8 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain SspB PF04386.13 EHT98485.1 - 8.4e-44 149.3 0.0 9.4e-44 149.1 0.0 1.0 1 0 0 1 1 1 1 Stringent starvation protein B FAD_binding_1 PF00667.20 EHT98486.1 - 4.9e-33 114.6 0.0 1.2e-31 110.0 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EHT98486.1 - 3.6e-31 108.3 0.0 6.4e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EHT98486.1 - 5.6e-19 68.8 0.0 3e-18 66.4 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Glu_synthase PF01645.17 EHT98487.1 - 8e-107 357.6 12.2 2.4e-101 339.5 6.4 2.9 3 0 0 3 3 3 2 Conserved region in glutamate synthase GATase_2 PF00310.21 EHT98487.1 - 9.1e-87 291.5 0.0 1.5e-86 290.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.14 EHT98487.1 - 1.8e-75 254.0 0.1 4.1e-74 249.6 0.0 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 EHT98487.1 - 1.9e-52 177.7 5.8 4.4e-52 176.4 5.8 1.6 1 0 0 1 1 1 1 GXGXG motif HKR_ArcB_TM PF18415.1 EHT98488.1 - 4.1e-29 101.2 6.6 5e-29 100.9 5.5 1.8 1 1 1 2 2 2 1 Histidine kinase receptor ArcB trans-membrane domain HATPase_c PF02518.26 EHT98488.1 - 5.2e-29 101.0 0.1 1e-28 100.1 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EHT98488.1 - 2.8e-22 79.0 0.4 8.7e-22 77.4 0.4 1.9 1 0 0 1 1 1 1 Response regulator receiver domain PAS PF00989.25 EHT98488.1 - 2.7e-16 59.6 0.0 6.2e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EHT98488.1 - 9.1e-15 54.9 0.3 4.8e-14 52.5 0.0 2.3 2 0 0 2 2 2 1 PAS fold HisKA PF00512.25 EHT98488.1 - 4.6e-14 52.2 2.7 1.5e-13 50.6 0.1 2.7 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Hpt PF01627.23 EHT98488.1 - 5.3e-12 45.8 5.4 8.5e-12 45.2 0.0 3.0 2 1 1 3 3 3 1 Hpt domain PAS_9 PF13426.7 EHT98488.1 - 7.4e-06 26.2 0.0 2.2e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 EHT98488.1 - 0.00086 19.3 0.1 0.0076 16.3 0.0 2.7 3 0 0 3 3 3 1 PAS domain HATPase_c_3 PF13589.6 EHT98488.1 - 0.0017 18.2 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CCB1 PF12046.8 EHT98488.1 - 0.014 14.7 0.2 0.029 13.7 0.2 1.5 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B ING PF12998.7 EHT98488.1 - 0.091 13.4 7.2 0.33 11.6 5.3 2.6 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding HATPase_c_2 PF13581.6 EHT98488.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Atg14 PF10186.9 EHT98488.1 - 0.24 10.4 3.8 0.41 9.7 3.8 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1840 PF08895.11 EHT98488.1 - 0.25 11.7 5.2 0.69 10.3 5.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) Fib_alpha PF08702.10 EHT98488.1 - 0.38 10.9 5.7 1 9.5 5.7 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 EHT98488.1 - 0.69 8.7 9.8 1.4 7.7 9.8 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.12 EHT98488.1 - 3.4 7.7 5.9 7.9 6.5 5.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) CREPT PF16566.5 EHT98488.1 - 9 6.5 11.4 70 3.6 0.5 2.6 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Transgly PF00912.22 EHT98489.1 - 2.2e-46 157.5 0.0 2.9e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 Transglycosylase PTS-HPr PF00381.19 EHT98490.1 - 3.7e-22 78.4 0.7 4.1e-22 78.2 0.7 1.0 1 0 0 1 1 1 1 PTS HPr component phosphorylation site ATP_bind_2 PF03668.15 EHT98491.1 - 2.3e-144 479.9 0.0 2.7e-144 479.7 0.0 1.0 1 0 0 1 1 1 1 P-loop ATPase protein family AAA_18 PF13238.6 EHT98491.1 - 0.05 14.2 0.0 0.77 10.3 0.0 2.7 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EHT98491.1 - 0.057 12.8 0.2 0.13 11.6 0.2 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family DnaB_C PF03796.15 EHT98491.1 - 0.058 12.7 0.0 0.33 10.2 0.0 1.9 1 1 1 2 2 2 0 DnaB-like helicase C terminal domain CPT PF07931.12 EHT98491.1 - 0.062 13.1 0.0 2 8.2 0.0 2.2 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.6 EHT98491.1 - 0.093 13.1 0.1 0.22 11.9 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 EHT98491.1 - 0.1 12.7 0.0 0.36 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EHT98491.1 - 0.11 12.7 0.1 0.33 11.2 0.1 2.1 1 1 0 1 1 1 0 AAA domain PTS_EIIA_2 PF00359.22 EHT98492.1 - 2.6e-37 127.9 0.0 2.9e-37 127.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Ribosomal_S30AE PF02482.19 EHT98493.1 - 4.2e-26 91.5 0.3 4.7e-26 91.4 0.3 1.0 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein Sigma54_DBD PF04552.13 EHT98494.1 - 2.6e-70 235.3 0.5 4.6e-70 234.5 0.5 1.4 1 0 0 1 1 1 1 Sigma-54, DNA binding domain Sigma54_CBD PF04963.13 EHT98494.1 - 7.9e-62 208.3 0.2 7.9e-62 208.3 0.2 1.7 2 0 0 2 2 2 1 Sigma-54 factor, core binding domain Sigma54_AID PF00309.20 EHT98494.1 - 8.2e-15 54.4 20.2 1.9e-14 53.2 20.2 1.7 1 0 0 1 1 1 1 Sigma-54 factor, Activator interacting domain (AID) ABC_tran PF00005.27 EHT98495.1 - 3.8e-34 118.1 0.0 6.1e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter BCA_ABC_TP_C PF12399.8 EHT98495.1 - 4.6e-08 32.8 0.0 1e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_21 PF13304.6 EHT98495.1 - 0.0006 19.7 1.5 0.25 11.1 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EHT98495.1 - 0.0087 15.5 0.1 3.5 7.0 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 EHT98495.1 - 0.015 14.4 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 EHT98495.1 - 0.054 14.0 0.1 0.11 13.0 0.0 1.4 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EHT98495.1 - 0.057 13.7 0.2 0.85 9.9 0.2 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit OstA PF03968.14 EHT98496.1 - 4.1e-31 107.5 1.3 5.6e-31 107.1 1.3 1.2 1 0 0 1 1 1 1 OstA-like protein Cna_B PF05738.13 EHT98496.1 - 0.058 13.9 0.2 0.12 13.0 0.2 1.5 1 1 0 1 1 1 0 Cna protein B-type domain LptC PF06835.13 EHT98497.1 - 6.6e-57 191.9 1.2 7.9e-57 191.7 1.2 1.0 1 0 0 1 1 1 1 Lipopolysaccharide-assembly, LptC-related Hydrolase_3 PF08282.12 EHT98498.1 - 9.3e-12 45.2 0.0 3.4e-10 40.1 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EHT98498.1 - 0.0023 18.0 0.0 0.013 15.5 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase SIS PF01380.22 EHT98499.1 - 3.3e-34 117.5 0.1 4.9e-34 117.0 0.1 1.3 1 0 0 1 1 1 1 SIS domain CBS PF00571.28 EHT98499.1 - 1.1e-12 48.2 8.8 3.5e-06 27.4 0.5 2.7 3 0 0 3 3 3 2 CBS domain SIS_2 PF13580.6 EHT98499.1 - 2.5e-05 24.3 1.5 0.005 16.9 0.1 2.4 1 1 1 2 2 2 2 SIS domain DUF2529 PF10740.9 EHT98499.1 - 0.077 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2529) Na_Ca_ex PF01699.24 EHT98500.1 - 1.4e-52 177.7 34.5 2.4e-26 92.5 14.3 2.0 2 0 0 2 2 2 2 Sodium/calcium exchanger protein ABC_tran PF00005.27 EHT98501.1 - 1e-30 107.0 0.0 1.4e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EHT98501.1 - 4.3e-08 33.3 0.0 0.0075 16.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EHT98501.1 - 3.4e-05 23.8 0.0 5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 EHT98501.1 - 0.0009 19.5 0.0 0.0015 18.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EHT98501.1 - 0.0012 19.3 0.0 0.0017 18.8 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 EHT98501.1 - 0.0029 17.2 1.8 0.042 13.4 1.8 2.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EHT98501.1 - 0.0072 16.1 0.2 0.015 15.0 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 EHT98501.1 - 0.0088 16.5 0.0 0.028 14.8 0.0 1.8 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 EHT98501.1 - 0.0095 15.8 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EHT98501.1 - 0.013 16.0 0.1 0.019 15.5 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EHT98501.1 - 0.02 14.7 0.1 0.032 13.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 EHT98501.1 - 0.046 12.5 2.2 0.7 8.6 0.8 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_14 PF13173.6 EHT98501.1 - 0.092 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EHT98501.1 - 0.11 12.5 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 NACHT domain RecA PF00154.21 EHT98501.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein MlaE PF02405.16 EHT98502.1 - 2.8e-74 249.4 16.7 4e-74 248.9 16.7 1.2 1 0 0 1 1 1 1 Permease MlaE MlaD PF02470.20 EHT98503.1 - 1.1e-19 70.5 0.0 1.5e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 MlaD protein MlaC PF05494.12 EHT98504.1 - 5e-52 176.0 0.1 5.9e-52 175.8 0.1 1.1 1 0 0 1 1 1 1 MlaC protein STAS_2 PF13466.6 EHT98505.1 - 1.9e-17 63.4 2.1 2.2e-17 63.2 2.1 1.1 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 EHT98505.1 - 1.1e-06 28.3 0.1 1.2e-06 28.2 0.1 1.2 1 0 0 1 1 1 1 STAS domain BolA PF01722.18 EHT98506.1 - 1.7e-12 47.5 0.0 1.9e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein GP70 PF17429.2 EHT98506.1 - 0.15 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Gene product 70 EPSP_synthase PF00275.20 EHT98507.1 - 1.4e-128 429.2 0.9 1.6e-128 428.9 0.9 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) HTH_35 PF13693.6 EHT98508.1 - 5e-39 132.2 0.4 5.9e-39 132.0 0.4 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_38 PF13936.6 EHT98508.1 - 0.0014 18.3 0.4 0.022 14.5 0.4 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_26 PF13443.6 EHT98508.1 - 0.013 15.9 0.0 0.084 13.3 0.0 1.9 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain HTH_3 PF01381.22 EHT98508.1 - 0.021 14.9 0.3 0.46 10.6 0.4 2.1 2 0 0 2 2 2 0 Helix-turn-helix HTH_IclR PF09339.10 EHT98508.1 - 0.033 14.0 1.1 0.056 13.3 1.1 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_28 PF13518.6 EHT98508.1 - 0.035 14.2 0.9 0.076 13.1 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain DprA_WH PF17782.1 EHT98508.1 - 0.046 13.8 0.1 0.063 13.4 0.1 1.2 1 0 0 1 1 1 0 DprA winged helix domain HTH_Tnp_ISL3 PF13542.6 EHT98508.1 - 0.052 13.0 0.6 0.17 11.3 0.2 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_20 PF12840.7 EHT98508.1 - 0.068 13.2 0.2 0.11 12.6 0.2 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_10 PF04967.12 EHT98508.1 - 0.072 12.9 0.0 0.19 11.5 0.1 1.7 2 0 0 2 2 2 0 HTH DNA binding domain HTH_AsnC-type PF13404.6 EHT98508.1 - 0.081 12.8 0.3 1.2 9.0 0.9 2.2 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 EHT98508.1 - 0.12 12.0 0.4 0.2 11.2 0.4 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding polyprenyl_synt PF00348.17 EHT98509.1 - 2.6e-75 252.8 0.1 3.2e-75 252.5 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Ribosomal_L21p PF00829.21 EHT98510.1 - 3.2e-38 130.1 1.9 3.5e-38 129.9 1.9 1.0 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Ribosomal_L27 PF01016.19 EHT98511.1 - 2.2e-39 133.4 3.1 2.4e-39 133.2 3.1 1.0 1 0 0 1 1 1 1 Ribosomal L27 protein RCC1_2 PF13540.6 EHT98511.1 - 0.023 14.5 0.1 0.047 13.5 0.1 1.5 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat GTP1_OBG PF01018.22 EHT98512.1 - 2.5e-59 199.3 5.3 3.4e-59 198.9 5.3 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 EHT98512.1 - 5e-23 81.4 0.0 8.6e-23 80.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EHT98512.1 - 1.4e-08 34.4 0.0 1.2e-07 31.3 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 EHT98512.1 - 0.0023 16.9 0.2 1.9 7.4 0.1 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 EHT98512.1 - 0.065 13.1 0.0 0.4 10.6 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Gtr1_RagA PF04670.12 EHT98512.1 - 0.083 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MMR_HSR1_Xtn PF16897.5 EHT98512.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Peptidase_S13 PF02113.15 EHT98513.1 - 1.3e-158 528.4 0.0 1.5e-158 528.2 0.0 1.0 1 0 0 1 1 1 1 D-Ala-D-Ala carboxypeptidase 3 (S13) family Beta-lactamase2 PF13354.6 EHT98513.1 - 7.4e-08 32.2 0.0 1.2e-05 25.1 0.0 2.7 2 1 0 2 2 2 2 Beta-lactamase enzyme family Transpeptidase PF00905.22 EHT98513.1 - 0.014 14.6 0.2 0.79 8.9 0.0 2.7 2 1 1 3 3 3 0 Penicillin binding protein transpeptidase domain GreA_GreB_N PF03449.15 EHT98514.1 - 2e-32 111.1 2.6 2.8e-32 110.7 2.6 1.2 1 0 0 1 1 1 1 Transcription elongation factor, N-terminal GreA_GreB PF01272.19 EHT98514.1 - 2e-28 98.1 0.1 2.8e-28 97.6 0.1 1.2 1 0 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term CRS1_YhbY PF01985.21 EHT98515.1 - 1.5e-22 79.6 0.5 1.7e-22 79.4 0.5 1.0 1 0 0 1 1 1 1 CRS1 / YhbY (CRM) domain FtsJ PF01728.19 EHT98516.1 - 2e-60 203.9 0.0 2.5e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 EHT98516.1 - 0.0032 18.1 0.1 0.15 12.7 0.1 2.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 EHT98516.1 - 0.011 15.4 0.0 0.024 14.3 0.0 1.7 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_23 PF13489.6 EHT98516.1 - 0.03 14.1 0.0 0.27 11.0 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Reovirus_L2 PF06016.11 EHT98516.1 - 0.088 10.0 0.0 0.1 9.8 0.0 1.0 1 0 0 1 1 1 0 Reovirus core-spike protein lambda-2 (L2) Methyltransf_31 PF13847.6 EHT98516.1 - 0.097 12.5 0.0 1.4 8.7 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 EHT98516.1 - 0.19 11.0 0.2 0.56 9.5 0.0 1.8 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family Peptidase_M41 PF01434.18 EHT98517.1 - 1.4e-73 246.9 0.4 2.5e-73 246.0 0.4 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EHT98517.1 - 2.3e-46 157.5 0.0 6.9e-46 156.0 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.15 EHT98517.1 - 6.6e-17 61.8 0.2 6.6e-17 61.8 0.2 1.9 2 0 0 2 2 2 1 FtsH Extracellular AAA_lid_3 PF17862.1 EHT98517.1 - 1.7e-11 43.7 0.1 3.6e-11 42.7 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EHT98517.1 - 3.2e-06 27.2 0.0 1.5e-05 25.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EHT98517.1 - 6.7e-06 25.5 0.0 1.2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 EHT98517.1 - 0.0002 21.1 0.0 0.00099 18.9 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EHT98517.1 - 0.0019 18.4 0.0 0.0047 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EHT98517.1 - 0.002 18.5 0.9 0.048 14.0 0.1 2.6 2 1 1 3 3 2 1 AAA ATPase domain AAA_2 PF07724.14 EHT98517.1 - 0.0033 17.6 0.2 0.017 15.2 0.0 2.4 3 0 0 3 3 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EHT98517.1 - 0.0034 17.1 0.0 0.0088 15.8 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EHT98517.1 - 0.0039 16.6 0.2 0.0095 15.3 0.2 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI CSTF2_hinge PF14327.6 EHT98517.1 - 0.0074 16.7 0.1 0.02 15.3 0.1 1.7 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 AAA_22 PF13401.6 EHT98517.1 - 0.0082 16.4 0.1 0.2 11.9 0.1 2.5 1 1 1 2 2 2 1 AAA domain ABC_tran PF00005.27 EHT98517.1 - 0.026 15.0 0.3 0.23 12.0 0.1 2.4 2 0 0 2 2 2 0 ABC transporter Zeta_toxin PF06414.12 EHT98517.1 - 0.05 12.9 0.1 0.12 11.6 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.26 EHT98517.1 - 0.052 13.2 0.0 0.29 10.8 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 EHT98517.1 - 0.076 12.5 0.2 0.22 11.0 0.2 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EHT98517.1 - 0.1 12.3 0.1 0.42 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EHT98517.1 - 0.11 11.9 0.3 0.24 10.8 0.3 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_17 PF13207.6 EHT98517.1 - 0.11 12.9 0.0 0.36 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 EHT98517.1 - 0.12 12.5 0.0 0.35 11.0 0.0 1.7 2 0 0 2 2 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 EHT98517.1 - 0.14 12.2 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_PrkA PF08298.11 EHT98517.1 - 0.14 11.0 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain ParB_C PF18064.1 EHT98517.1 - 0.15 12.3 0.1 7 6.9 0.0 2.6 2 0 0 2 2 2 0 Centromere-binding protein ParB C-terminal AAA_28 PF13521.6 EHT98517.1 - 0.15 12.3 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Pterin_bind PF00809.22 EHT98518.1 - 4.5e-89 298.3 0.1 5.3e-89 298.1 0.1 1.0 1 0 0 1 1 1 1 Pterin binding enzyme PGM_PMM_I PF02878.16 EHT98519.1 - 6.4e-46 155.5 0.0 1.3e-45 154.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EHT98519.1 - 2.6e-32 111.4 0.1 5.2e-32 110.4 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EHT98519.1 - 1.3e-19 70.7 0.0 2.8e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EHT98519.1 - 1.9e-15 56.8 1.1 5.3e-15 55.3 1.1 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain SecG PF03840.14 EHT98520.1 - 5.9e-22 77.5 11.8 7.3e-22 77.2 11.8 1.1 1 0 0 1 1 1 1 Preprotein translocase SecG subunit PulG PF11773.8 EHT98520.1 - 0.14 12.0 0.6 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 Type II secretory pathway pseudopilin CPP1-like PF11833.8 EHT98520.1 - 5.9 6.5 5.6 13 5.3 5.1 1.7 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF150 PF02576.17 EHT98521.1 - 4.3e-28 97.5 0.2 8.7e-28 96.5 0.2 1.5 1 0 0 1 1 1 1 RimP N-terminal domain DUF150_C PF17384.2 EHT98521.1 - 3.8e-21 75.0 0.0 5.7e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 RimP C-terminal SH3 domain NusA_N PF08529.11 EHT98522.1 - 3.5e-37 127.5 6.8 9.9e-37 126.0 6.8 1.8 1 0 0 1 1 1 1 NusA N-terminal domain KH_5 PF13184.6 EHT98522.1 - 9.4e-30 102.5 2.4 8.7e-28 96.2 0.2 3.1 3 0 0 3 3 3 1 NusA-like KH domain HHH_5 PF14520.6 EHT98522.1 - 2e-17 63.5 2.8 5.4e-11 42.9 0.2 3.1 3 0 0 3 3 3 2 Helix-hairpin-helix domain S1 PF00575.23 EHT98522.1 - 3.3e-05 24.1 0.1 0.00013 22.2 0.1 2.1 1 0 0 1 1 1 1 S1 RNA binding domain KH_2 PF07650.17 EHT98522.1 - 0.0037 17.1 1.6 0.033 14.0 0.0 3.2 3 0 0 3 3 3 1 KH domain DUF4332 PF14229.6 EHT98522.1 - 0.0095 16.2 0.2 7 6.9 0.0 2.7 1 1 0 2 2 2 2 Domain of unknown function (DUF4332) KH_4 PF13083.6 EHT98522.1 - 0.037 13.9 0.1 0.3 11.0 0.0 2.6 2 0 0 2 2 2 0 KH domain HHH_3 PF12836.7 EHT98522.1 - 0.088 13.1 0.1 7.2 6.9 0.0 3.5 2 1 0 2 2 2 0 Helix-hairpin-helix motif HHH_2 PF12826.7 EHT98522.1 - 0.16 12.1 4.5 1.9 8.6 0.2 3.1 3 0 0 3 3 3 0 Helix-hairpin-helix motif IF-2 PF11987.8 EHT98523.1 - 3.4e-37 126.8 1.2 1.3e-36 124.9 1.2 2.1 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU PF00009.27 EHT98523.1 - 2e-33 115.6 1.8 2e-33 115.6 1.8 3.7 3 2 0 3 3 2 1 Elongation factor Tu GTP binding domain IF2_N PF04760.15 EHT98523.1 - 3.2e-23 81.3 5.8 1.8e-13 50.0 1.8 2.7 2 0 0 2 2 2 2 Translation initiation factor IF-2, N-terminal region IF2_assoc PF08364.11 EHT98523.1 - 1.2e-15 57.4 7.4 1.6e-15 57.1 5.4 2.4 2 0 0 2 2 2 1 Bacterial translation initiation factor IF-2 associated region MMR_HSR1 PF01926.23 EHT98523.1 - 8.9e-10 38.7 0.1 2.7e-09 37.1 0.1 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 EHT98523.1 - 1.6e-08 34.8 3.2 5.7e-06 26.6 0.3 3.3 2 1 0 2 2 2 2 Elongation factor Tu domain 2 Ras PF00071.22 EHT98523.1 - 5.9e-06 26.0 0.0 1.9e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 Ras family Arf PF00025.21 EHT98523.1 - 0.00019 20.9 0.0 0.00062 19.3 0.0 1.9 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EHT98523.1 - 0.00031 20.7 3.0 0.079 12.9 0.0 3.6 2 1 1 3 3 3 1 RsgA GTPase FeoB_N PF02421.18 EHT98523.1 - 0.00091 18.8 0.1 0.0026 17.3 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 EHT98523.1 - 0.0026 17.2 0.0 0.0094 15.4 0.0 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EHT98523.1 - 0.0041 17.3 0.0 0.01 16.0 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 EHT98523.1 - 0.0096 15.7 1.5 0.02 14.7 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1_Xtn PF16897.5 EHT98523.1 - 0.064 13.3 0.9 0.29 11.2 0.0 2.5 3 0 0 3 3 3 0 C-terminal region of MMR_HSR1 domain AAA_26 PF13500.6 EHT98523.1 - 0.2 11.5 0.0 0.2 11.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain RBFA PF02033.18 EHT98524.1 - 6.5e-34 116.5 0.1 7.6e-34 116.3 0.1 1.1 1 0 0 1 1 1 1 Ribosome-binding factor A DUF3047 PF11249.8 EHT98524.1 - 0.033 13.6 0.0 0.046 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3047) Herpes_U30 PF04523.13 EHT98524.1 - 0.17 9.7 0.0 0.21 9.4 0.0 1.0 1 0 0 1 1 1 0 Herpes virus tegument protein U30 TruB_N PF01509.18 EHT98525.1 - 4.8e-58 195.7 0.0 6.8e-58 195.3 0.0 1.2 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EHT98525.1 - 1.3e-22 79.6 0.2 2.5e-22 78.8 0.2 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB-C_2 PF09157.11 EHT98525.1 - 2.5e-22 78.7 0.2 5.1e-22 77.7 0.2 1.6 1 0 0 1 1 1 1 Pseudouridine synthase II TruB, C-terminal Ribosomal_S15 PF00312.22 EHT98526.1 - 6.3e-37 125.7 0.8 7.1e-37 125.5 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S15 Stirrup PF09061.6 EHT98526.1 - 0.053 13.7 0.1 0.067 13.4 0.1 1.2 1 0 0 1 1 1 0 Stirrup RNase_PH PF01138.21 EHT98527.1 - 2.8e-42 144.3 0.0 3.9e-21 75.9 0.0 2.6 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 PNPase PF03726.14 EHT98527.1 - 2.1e-26 92.2 1.8 5.9e-26 90.8 1.8 1.8 1 0 0 1 1 1 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain RNase_PH_C PF03725.15 EHT98527.1 - 1.6e-23 82.5 1.4 4.1e-15 55.6 0.0 2.6 2 0 0 2 2 2 2 3' exoribonuclease family, domain 2 S1 PF00575.23 EHT98527.1 - 9.7e-22 77.1 3.5 9.7e-22 77.1 3.5 2.3 2 0 0 2 2 2 1 S1 RNA binding domain KH_1 PF00013.29 EHT98527.1 - 1.5e-08 34.3 4.6 1.5e-08 34.3 2.5 2.3 2 0 0 2 2 2 1 KH domain S1_2 PF13509.6 EHT98527.1 - 0.00017 21.6 0.1 0.0047 16.9 0.0 2.9 2 1 0 2 2 2 1 S1 domain KH_2 PF07650.17 EHT98527.1 - 0.0012 18.7 4.0 0.0013 18.5 0.5 2.7 2 0 0 2 2 2 1 KH domain TPR_2 PF07719.17 EHT98528.1 - 3.5e-17 61.1 15.0 3.8e-05 23.5 0.0 5.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 EHT98528.1 - 5.3e-16 57.7 15.8 5.2e-06 26.0 0.1 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 EHT98528.1 - 1.5e-11 44.3 5.5 8.5e-06 25.8 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EHT98528.1 - 1.6e-09 37.3 11.9 5.4e-05 22.8 2.5 5.1 5 1 1 6 6 6 2 TPR repeat TPR_19 PF14559.6 EHT98528.1 - 1.9e-09 37.9 2.2 3.3e-05 24.3 0.0 4.1 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EHT98528.1 - 2.1e-09 37.4 5.8 0.0071 17.1 0.0 5.0 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EHT98528.1 - 6.6e-09 35.3 12.6 0.0071 16.5 0.0 4.8 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EHT98528.1 - 2.6e-07 31.2 17.6 0.0014 19.3 0.1 4.5 3 2 2 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 EHT98528.1 - 4.6e-05 23.6 13.6 0.012 15.9 1.1 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 EHT98528.1 - 0.00017 21.8 12.3 0.68 10.5 0.0 5.2 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 EHT98528.1 - 0.017 15.8 17.5 4.7 8.1 0.1 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 EHT98528.1 - 0.034 14.0 13.2 1.2 9.1 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat RPN7 PF10602.9 EHT98528.1 - 0.037 13.7 1.8 0.31 10.7 0.2 2.8 2 1 0 2 2 2 0 26S proteasome subunit RPN7 TPR_7 PF13176.6 EHT98528.1 - 0.068 13.2 13.2 1.1 9.4 0.0 4.9 5 1 0 5 5 5 0 Tetratricopeptide repeat DEAD PF00270.29 EHT98529.1 - 5.6e-52 176.0 0.0 2.7e-51 173.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EHT98529.1 - 2.9e-30 104.9 0.0 1e-28 99.9 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DbpA PF03880.15 EHT98529.1 - 1.3e-20 73.1 0.0 3.1e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 DbpA RNA binding domain ResIII PF04851.15 EHT98529.1 - 0.00063 19.8 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EHT98529.1 - 0.0028 17.0 1.3 0.0043 16.4 0.0 2.0 2 1 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.6 EHT98529.1 - 0.036 13.8 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain DRTGG PF07085.12 EHT98529.1 - 0.15 11.9 0.1 0.54 10.1 0.0 1.9 2 0 0 2 2 2 0 DRTGG domain Bac_luciferase PF00296.20 EHT98530.1 - 1.2e-32 113.6 1.7 3.6e-32 112.1 1.7 1.6 1 1 0 1 1 1 1 Luciferase-like monooxygenase Peptidase_U32 PF01136.19 EHT98531.1 - 3.4e-10 39.5 0.0 4.5e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family U32 Peptidase_U32 PF01136.19 EHT98532.1 - 4e-64 216.0 0.0 5.2e-64 215.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family U32 AP_endonuc_2 PF01261.24 EHT98532.1 - 0.0048 16.4 0.5 0.0081 15.6 0.5 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel SCP2 PF02036.17 EHT98533.1 - 3.6e-16 59.5 0.2 5.3e-16 59.0 0.2 1.3 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 EHT98533.1 - 0.00064 20.0 0.1 0.0012 19.1 0.1 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Acetyltransf_1 PF00583.25 EHT98534.1 - 2.7e-07 30.8 0.0 4.1e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EHT98534.1 - 7.5e-06 26.3 0.0 1.1e-05 25.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EHT98534.1 - 0.001 19.2 0.1 0.0027 17.8 0.0 1.7 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 EHT98534.1 - 0.0018 18.3 0.0 0.0037 17.3 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EHT98534.1 - 0.0066 16.4 0.0 0.0087 16.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GIY-YIG PF01541.24 EHT98535.1 - 3.6e-11 43.2 0.0 4.2e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 GIY-YIG catalytic domain Putative_PNPOx PF01243.20 EHT98536.1 - 0.0012 19.0 0.0 0.0015 18.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase SSFA2_C PF14723.6 EHT98536.1 - 0.019 14.9 0.0 0.021 14.7 0.0 1.1 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus DJ-1_PfpI PF01965.24 EHT98537.1 - 1.9e-53 180.6 0.1 2.2e-53 180.4 0.1 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 EHT98537.1 - 5.8e-05 22.9 0.0 6.9e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EHT98537.1 - 0.00087 19.1 0.0 0.0026 17.6 0.0 1.8 1 1 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.14 EHT98537.1 - 0.0026 17.4 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 EHT98537.1 - 0.028 14.3 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 SNO glutamine amidotransferase family Catalase_C PF18011.1 EHT98537.1 - 0.071 12.7 0.1 0.089 12.4 0.1 1.3 1 0 0 1 1 1 0 C-terminal domain found in long catalases ThiJ_like PF17124.5 EHT98537.1 - 0.12 12.1 0.0 0.29 10.8 0.0 1.7 1 1 0 1 1 1 0 ThiJ/PfpI family-like Epimerase PF01370.21 EHT98538.1 - 2.3e-05 24.0 0.0 9e-05 22.0 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EHT98538.1 - 0.0003 20.1 0.0 0.018 14.2 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 EHT98538.1 - 0.00035 20.5 0.0 0.00056 19.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding HIM1 PF08732.10 EHT98538.1 - 0.00037 20.0 0.0 0.00057 19.5 0.0 1.2 1 0 0 1 1 1 1 HIM1 Semialdhyde_dh PF01118.24 EHT98538.1 - 0.0016 18.9 0.0 0.0056 17.1 0.0 1.9 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 EHT98538.1 - 0.027 13.6 0.0 0.64 9.1 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EHT98538.1 - 0.033 13.6 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Fer4_12 PF13353.6 EHT98539.1 - 3.7e-48 163.3 0.0 4.1e-48 163.2 0.0 1.0 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EHT98539.1 - 1.7e-31 108.8 0.0 2.1e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 4Fe-4S single cluster domain Radical_SAM PF04055.21 EHT98539.1 - 0.0024 18.3 0.0 0.0029 18.0 0.0 1.1 1 0 0 1 1 1 1 Radical SAM superfamily NRDD PF13597.6 EHT98540.1 - 1.6e-177 591.8 0.0 2e-177 591.4 0.0 1.1 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase Gly_radical PF01228.21 EHT98540.1 - 1.3e-27 96.4 0.0 4.4e-27 94.7 0.0 1.9 2 0 0 2 2 2 1 Glycine radical ATP-cone PF03477.16 EHT98540.1 - 4.3e-21 75.3 0.4 2.8e-20 72.7 0.1 2.2 2 0 0 2 2 2 1 ATP cone domain DUF4051 PF13260.6 EHT98540.1 - 0.08 12.7 0.5 0.18 11.5 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) OrfB_Zn_ribbon PF07282.11 EHT98540.1 - 1.2 9.1 5.8 0.45 10.5 2.3 2.2 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Glyco_hydro_20 PF00728.22 EHT98541.1 - 1.7e-99 333.5 0.1 8.5e-98 328.0 0.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 EHT98541.1 - 2e-15 57.7 0.1 2.3e-14 54.2 0.0 2.6 3 0 0 3 3 3 1 Glycosyl hydrolase family 20, domain 2 Glycohydro_20b2 PF14845.6 EHT98541.1 - 2.7e-08 34.6 0.1 8e-08 33.0 0.0 1.8 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Peripla_BP_3 PF13377.6 EHT98543.1 - 7e-38 130.6 2.6 1.1e-37 129.9 0.3 2.3 2 1 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 EHT98543.1 - 5.3e-31 108.1 0.2 9.1e-31 107.3 0.0 1.4 2 0 0 2 2 2 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 EHT98543.1 - 5.1e-21 74.2 1.1 5.1e-21 74.2 1.1 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 EHT98543.1 - 5e-12 45.9 0.0 1.2e-11 44.7 0.0 1.7 1 1 0 1 1 1 1 Periplasmic binding protein domain HTH_Tnp_ISL3 PF13542.6 EHT98543.1 - 2.2e-05 23.8 0.5 0.0033 16.8 0.3 3.2 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_3 PF01381.22 EHT98543.1 - 0.011 15.8 0.0 0.023 14.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix HTH_31 PF13560.6 EHT98543.1 - 0.019 15.3 0.3 0.091 13.1 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 EHT98543.1 - 0.024 14.4 0.0 0.14 12.0 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain HpcH_HpaI PF03328.14 EHT98543.1 - 0.042 13.0 0.7 1 8.5 0.1 2.2 2 0 0 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family HTH_17 PF12728.7 EHT98543.1 - 0.05 13.8 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain MerR PF00376.23 EHT98543.1 - 0.052 13.3 0.2 0.11 12.3 0.2 1.5 1 0 0 1 1 1 0 MerR family regulatory protein DUF3853 PF12964.7 EHT98543.1 - 0.072 13.3 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3853) HTH_26 PF13443.6 EHT98543.1 - 0.074 13.5 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_38 PF13936.6 EHT98543.1 - 0.092 12.5 1.1 0.43 10.4 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain SAND PF01342.21 EHT98543.1 - 0.094 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 SAND domain Trp_repressor PF01371.19 EHT98543.1 - 0.13 12.4 0.1 0.34 11.1 0.1 1.7 1 0 0 1 1 1 0 Trp repressor protein HTH_Crp_2 PF13545.6 EHT98543.1 - 0.2 11.6 0.5 1.4 8.9 0.0 2.5 3 1 0 3 3 3 0 Crp-like helix-turn-helix domain HTH_24 PF13412.6 EHT98543.1 - 0.22 11.1 0.5 1.6 8.3 0.1 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Molybdopterin PF00384.22 EHT98544.1 - 2.7e-64 217.7 0.0 3.3e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 EHT98544.1 - 3.2e-27 94.8 0.0 8.1e-27 93.5 0.0 1.7 2 0 0 2 2 2 1 Molydopterin dinucleotide binding domain Molybdopterin_N PF18364.1 EHT98544.1 - 7.8e-17 61.0 0.0 1.7e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin oxidoreductase N-terminal domain Transpeptidase PF00905.22 EHT98545.1 - 9.5e-74 248.3 0.0 1.2e-73 248.0 0.0 1.1 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain PBP_dimer PF03717.15 EHT98545.1 - 1.2e-14 55.1 0.0 1.5e-13 51.5 0.0 2.2 1 1 0 1 1 1 1 Penicillin-binding Protein dimerisation domain MFS_1 PF07690.16 EHT98546.1 - 3.8e-17 62.2 41.3 3.8e-17 62.2 41.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 EHT98546.1 - 1.1 8.9 10.9 2.6 7.8 0.1 3.0 2 1 0 3 3 3 0 Ion channel regulatory protein UNC-93 4HB_MCP_1 PF12729.7 EHT98547.1 - 0.00022 20.8 0.5 0.00023 20.8 0.5 1.0 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction TarH PF02203.15 EHT98547.1 - 0.06 13.3 2.0 0.062 13.2 2.0 1.0 1 0 0 1 1 1 0 Tar ligand binding domain homologue DDE_Tnp_1 PF01609.21 EHT98549.1 - 5.5e-20 71.9 0.0 1e-19 71.0 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain MCPsignal PF00015.21 EHT98550.1 - 2.9e-46 157.4 32.9 4.2e-45 153.6 18.2 2.6 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 EHT98550.1 - 5.2e-05 23.4 24.0 0.048 13.9 0.0 4.6 1 1 5 6 6 6 4 Bacterial protein of unknown function (DUF948) HAMP PF00672.25 EHT98550.1 - 8.5e-05 22.9 0.8 8.5e-05 22.9 0.8 4.3 4 1 1 5 5 5 1 HAMP domain DUF1664 PF07889.12 EHT98550.1 - 0.00018 21.5 12.8 0.058 13.4 3.2 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF1664) Tweety PF04906.13 EHT98550.1 - 0.0015 17.3 2.1 0.0015 17.3 2.1 2.1 2 0 0 2 2 2 1 Tweety Nup54 PF13874.6 EHT98550.1 - 0.018 15.2 0.3 0.018 15.2 0.3 2.9 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 APG6_N PF17675.1 EHT98550.1 - 0.03 14.8 9.5 0.034 14.7 2.2 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4559 PF15112.6 EHT98550.1 - 0.076 12.7 4.9 0.061 13.0 1.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) Spc7 PF08317.11 EHT98550.1 - 0.16 10.8 12.4 0.43 9.4 2.1 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein IFT57 PF10498.9 EHT98550.1 - 0.24 10.3 11.7 0.27 10.1 1.6 2.1 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 T7SS_ESX_EspC PF10824.8 EHT98550.1 - 0.62 10.6 34.0 0.39 11.2 8.3 4.7 2 2 2 4 4 4 0 Excreted virulence factor EspC, type VII ESX diderm DUF3450 PF11932.8 EHT98550.1 - 2.6 7.3 21.5 1.5 8.1 8.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) PTPA PF03095.15 EHT98550.1 - 3.6 6.9 5.1 5.4 6.4 0.8 2.1 2 0 0 2 2 2 0 Phosphotyrosyl phosphate activator (PTPA) protein Spectrin PF00435.21 EHT98550.1 - 4.1 7.9 8.1 2.6 8.6 0.1 3.2 2 2 2 4 4 4 0 Spectrin repeat Laminin_II PF06009.12 EHT98550.1 - 5 7.1 25.5 0.71 9.9 5.7 3.9 1 1 2 4 4 4 0 Laminin Domain II Sec8_exocyst PF04048.14 EHT98550.1 - 9.2 6.2 17.9 2.3 8.1 1.9 3.9 2 2 2 4 4 4 0 Sec8 exocyst complex component specific domain Ribonuc_L-PSP PF01042.21 EHT98551.1 - 3.3e-45 153.0 0.7 3.7e-45 152.8 0.7 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP YjgF_endoribonc PF14588.6 EHT98551.1 - 0.055 13.6 0.1 0.09 12.9 0.1 1.5 1 1 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease PyrI PF01948.18 EHT98552.1 - 4.4e-31 107.0 0.0 6.1e-31 106.5 0.0 1.2 1 0 0 1 1 1 1 Aspartate carbamoyltransferase regulatory chain, allosteric domain PyrI_C PF02748.15 EHT98552.1 - 9.7e-17 60.6 1.5 1.5e-16 60.1 1.5 1.3 1 0 0 1 1 1 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain OTCace_N PF02729.21 EHT98553.1 - 8.1e-46 155.7 0.1 1.6e-45 154.7 0.0 1.5 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 EHT98553.1 - 2.9e-26 92.4 0.0 4.3e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain BRCT PF00533.26 EHT98553.1 - 0.13 12.6 0.0 0.55 10.7 0.0 2.0 2 1 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain OTCace PF00185.24 EHT98555.1 - 8.6e-55 185.1 0.1 3.8e-54 183.0 0.1 1.8 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 EHT98555.1 - 6.2e-48 162.6 0.0 8.9e-48 162.1 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain RraB PF06877.11 EHT98556.1 - 3.8e-33 114.3 0.2 5.5e-33 113.7 0.2 1.2 1 0 0 1 1 1 1 Regulator of ribonuclease activity B MiaE PF06175.11 EHT98557.1 - 3e-107 357.7 0.5 3.4e-107 357.5 0.5 1.0 1 0 0 1 1 1 1 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) Acetyltransf_1 PF00583.25 EHT98558.1 - 1.3e-13 51.2 0.0 1.6e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EHT98558.1 - 2.3e-10 40.7 0.0 3.4e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EHT98558.1 - 2.9e-07 30.5 0.0 3.6e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EHT98558.1 - 0.00013 21.8 0.0 0.00023 21.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EHT98558.1 - 0.001 19.2 0.0 0.0017 18.5 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 EHT98558.1 - 0.001 19.8 0.0 0.0012 19.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EHT98558.1 - 0.029 14.5 0.0 0.031 14.4 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain tRNA-synt_1 PF00133.22 EHT98559.1 - 1.1e-231 770.4 0.5 1.3e-230 766.8 0.5 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EHT98559.1 - 4.1e-46 156.7 0.3 9.3e-46 155.5 0.3 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EHT98559.1 - 1.5e-18 66.8 0.3 1.1e-07 31.0 0.1 4.7 4 1 0 4 4 4 3 tRNA synthetases class I (M) Val_tRNA-synt_C PF10458.9 EHT98559.1 - 1.1e-17 64.0 7.3 3e-17 62.7 7.3 1.7 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1_2 PF13603.6 EHT98559.1 - 1.4e-07 31.2 0.0 2.3e-05 24.0 0.0 2.4 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1f PF01921.18 EHT98559.1 - 0.029 13.3 0.0 0.067 12.1 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (K) ABC_tran_CTD PF16326.5 EHT98559.1 - 0.036 14.3 5.1 0.097 12.9 5.1 1.7 1 0 0 1 1 1 0 ABC transporter C-terminal domain Herpes_BLRF2 PF05812.12 EHT98559.1 - 0.68 10.1 3.0 1.4 9.1 1.4 2.3 3 0 0 3 3 3 0 Herpesvirus BLRF2 protein tRNA-synt_1b PF00579.25 EHT98559.1 - 3 7.1 6.0 0.41 9.9 0.0 2.3 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) DNA_pol3_chi PF04364.13 EHT98560.1 - 1.4e-41 141.8 0.0 1.6e-41 141.7 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase III chi subunit, HolC Peptidase_M17 PF00883.21 EHT98561.1 - 2.4e-123 411.4 0.1 4e-123 410.7 0.1 1.4 2 0 0 2 2 2 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 EHT98561.1 - 5e-34 116.9 0.0 1.8e-33 115.1 0.0 2.0 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain LptF_LptG PF03739.14 EHT98562.1 - 1.9e-72 244.0 8.4 2.3e-72 243.8 8.4 1.0 1 0 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG Claudin_2 PF13903.6 EHT98562.1 - 0.003 17.4 2.3 0.003 17.4 2.3 2.5 2 1 0 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction LptF_LptG PF03739.14 EHT98563.1 - 2.3e-74 250.4 6.3 2.7e-74 250.2 6.3 1.0 1 0 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG SH3_2 PF07653.17 EHT98564.1 - 8.1e-13 47.9 0.0 3.8e-05 23.3 0.0 2.1 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 EHT98564.1 - 1.3e-08 34.5 1.4 0.001 18.9 0.1 2.1 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 EHT98564.1 - 7.1e-07 28.7 0.4 8.2e-05 22.1 0.0 2.1 2 0 0 2 2 2 2 SH3 domain SH3_4 PF06347.13 EHT98564.1 - 0.0016 18.2 0.3 0.0016 18.2 0.3 2.6 2 1 0 2 2 2 1 Bacterial SH3 domain SH3_3 PF08239.11 EHT98564.1 - 0.041 14.2 2.7 0.11 12.8 0.2 2.1 2 0 0 2 2 2 0 Bacterial SH3 domain Peptidase_M20 PF01546.28 EHT98565.1 - 3.5e-29 102.0 0.0 4.3e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EHT98565.1 - 2.7e-21 75.5 0.0 4.6e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EHT98565.1 - 5.8e-05 22.9 0.0 9.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 GATase1_like PF07090.11 EHT98566.1 - 6.9e-110 366.3 0.4 7.8e-110 366.1 0.4 1.0 1 0 0 1 1 1 1 Putative glutamine amidotransferase PTE PF02126.18 EHT98567.1 - 2.2e-67 227.6 0.0 2.6e-67 227.4 0.0 1.0 1 0 0 1 1 1 1 Phosphotriesterase family BPD_transp_2 PF02653.16 EHT98568.1 - 4e-46 157.4 42.7 4e-46 157.4 42.7 1.4 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component ABC_tran PF00005.27 EHT98569.1 - 7.6e-13 49.2 0.0 1.1e-12 48.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EHT98569.1 - 7.9e-06 25.9 0.0 9.4e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EHT98569.1 - 7.9e-05 22.2 0.0 9.4e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 EHT98569.1 - 0.00061 18.7 0.2 0.0048 15.8 0.2 1.9 1 1 0 1 1 1 1 Predicted ATPase of the ABC class Peripla_BP_3 PF13377.6 EHT98570.1 - 8.1e-40 136.9 0.2 1.7e-37 129.3 0.1 2.2 2 0 0 2 2 2 2 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 EHT98570.1 - 9.7e-39 133.5 0.0 1.8e-38 132.6 0.0 1.4 2 0 0 2 2 2 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 EHT98570.1 - 2e-14 53.8 0.0 2.9e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain LacI PF00356.21 EHT98570.1 - 5e-14 51.8 0.0 3.9e-12 45.8 0.0 2.4 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family HTH_3 PF01381.22 EHT98570.1 - 0.00016 21.6 0.1 0.00041 20.4 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EHT98570.1 - 0.00022 21.5 0.3 0.028 14.8 0.0 2.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_IclR PF09339.10 EHT98570.1 - 0.0051 16.6 0.0 0.018 14.8 0.0 2.0 1 0 0 1 1 1 1 IclR helix-turn-helix domain PsiB PF06290.11 EHT98570.1 - 0.13 11.7 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 Plasmid SOS inhibition protein (PsiB) HTH_26 PF13443.6 EHT98570.1 - 0.15 12.5 0.1 0.31 11.5 0.1 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Peripla_BP_4 PF13407.6 EHT98571.1 - 1.9e-53 181.7 22.4 2.2e-53 181.5 22.4 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 EHT98571.1 - 8.8e-17 61.4 4.4 1.2e-16 61.0 4.4 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 EHT98571.1 - 3.4e-12 47.0 0.3 2.3e-10 41.0 0.0 2.1 2 0 0 2 2 2 2 Periplasmic binding protein-like domain PfkB PF00294.24 EHT98572.1 - 2.1e-35 122.5 3.5 4.5e-34 118.1 3.5 2.0 1 1 0 1 1 1 1 pfkB family carbohydrate kinase PhoH PF02562.16 EHT98572.1 - 0.031 13.7 0.2 0.075 12.5 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein BtpA PF03437.15 EHT98573.1 - 8.2e-70 235.1 0.1 9.6e-70 234.9 0.1 1.0 1 0 0 1 1 1 1 BtpA family Trp_syntA PF00290.20 EHT98573.1 - 0.00097 18.1 0.0 0.0015 17.4 0.0 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain RHH_1 PF01402.21 EHT98573.1 - 0.027 14.4 1.6 0.19 11.7 0.1 2.8 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family DUF445 PF04286.12 EHT98574.1 - 8.6e-103 345.0 0.3 9.8e-103 344.8 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF445) DUF1616 PF07760.11 EHT98574.1 - 0.02 14.3 0.1 0.028 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) DUF3206 PF11472.8 EHT98574.1 - 0.17 11.8 0.3 1.3 9.0 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3206) YtxH PF12732.7 EHT98574.1 - 0.31 11.6 2.1 32 5.1 0.0 3.5 2 1 0 2 2 2 0 YtxH-like protein DUF853 PF05872.12 EHT98576.1 - 1.7e-149 498.7 0.0 1.9e-149 498.5 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) Zot PF05707.12 EHT98576.1 - 0.00077 19.1 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_10 PF12846.7 EHT98576.1 - 0.071 12.0 0.0 0.092 11.7 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain TraG-D_C PF12696.7 EHT98576.1 - 0.074 13.0 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG DUF853 PF05872.12 EHT98577.1 - 1.4e-76 258.1 0.6 1.5e-76 258.0 0.6 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) DUF87 PF01935.17 EHT98577.1 - 2.4e-07 31.1 0.0 2.8e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 EHT98577.1 - 3.3e-05 23.0 0.1 4.6e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 EHT98577.1 - 9.6e-05 22.2 0.1 0.00013 21.7 0.1 1.2 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.18 EHT98577.1 - 0.00014 21.3 0.1 0.00023 20.6 0.1 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_22 PF13401.6 EHT98577.1 - 0.00022 21.5 0.4 0.00029 21.1 0.3 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EHT98577.1 - 0.00042 20.7 0.0 0.00044 20.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EHT98577.1 - 0.0011 19.1 0.0 0.0015 18.6 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_28 PF13521.6 EHT98577.1 - 0.0023 18.2 0.1 0.003 17.8 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EHT98577.1 - 0.0024 17.5 0.0 0.0026 17.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EHT98577.1 - 0.0031 17.1 0.0 0.0045 16.5 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region T2SSE PF00437.20 EHT98577.1 - 0.0044 16.1 0.0 0.0072 15.4 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.29 EHT98577.1 - 0.0047 17.3 0.0 0.0071 16.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 EHT98577.1 - 0.0048 16.9 0.1 0.0075 16.3 0.1 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 EHT98577.1 - 0.0055 17.1 0.1 0.0063 16.9 0.1 1.3 1 1 0 1 1 1 1 AAA ATPase domain SRP54 PF00448.22 EHT98577.1 - 0.012 15.2 0.5 0.022 14.4 0.5 1.4 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_6 PF12774.7 EHT98577.1 - 0.042 12.8 0.1 0.056 12.4 0.1 1.1 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_18 PF13238.6 EHT98577.1 - 0.053 14.1 0.0 0.076 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 EHT98577.1 - 0.055 12.4 0.0 0.068 12.1 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain NTPase_1 PF03266.15 EHT98577.1 - 0.055 13.4 0.2 0.083 12.8 0.2 1.2 1 0 0 1 1 1 0 NTPase DUF2075 PF09848.9 EHT98577.1 - 0.058 12.6 0.1 0.072 12.3 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 EHT98577.1 - 0.12 12.3 0.9 0.3 11.0 0.1 1.9 2 0 0 2 2 2 0 NACHT domain IPT PF01745.16 EHT98577.1 - 0.17 11.3 0.1 0.22 10.9 0.1 1.2 1 0 0 1 1 1 0 Isopentenyl transferase SBP_bac_5 PF00496.22 EHT98578.1 - 4.8e-62 210.1 2.6 6.1e-62 209.8 2.6 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle MarC PF01914.17 EHT98579.1 - 6.6e-64 215.0 11.2 7.5e-64 214.9 11.2 1.0 1 0 0 1 1 1 1 MarC family integral membrane protein PalH PF08733.10 EHT98579.1 - 0.65 8.9 3.3 0.18 10.8 0.3 1.5 2 0 0 2 2 2 0 PalH/RIM21 CPP1-like PF11833.8 EHT98579.1 - 0.83 9.3 8.6 0.084 12.5 3.7 1.8 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like TipAS PF07739.13 EHT98580.1 - 0.026 15.0 0.5 0.14 12.7 0.2 2.0 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Octopine_DH PF02317.17 EHT98580.1 - 0.052 13.6 0.1 0.1 12.7 0.1 1.5 1 1 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain DUF2501 PF10696.9 EHT98581.1 - 1.8e-25 89.0 5.3 1.8e-25 89.0 5.3 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF2501) CDC37_M PF08565.11 EHT98581.1 - 0.1 12.5 0.1 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 Cdc37 Hsp90 binding domain TraW_N PF12477.8 EHT98581.1 - 5.3 7.1 5.7 12 6.0 5.7 1.5 1 0 0 1 1 1 0 Sex factor F TraW protein N terminal Arm-DNA-bind_3 PF13356.6 EHT98582.1 - 3.7e-21 75.3 1.7 8.1e-21 74.2 1.7 1.6 1 0 0 1 1 1 1 Arm DNA-binding domain Pan3_PK PF18101.1 EHT98582.1 - 0.011 15.7 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 Pan3 Pseudokinase domain Phage_int_SAM_3 PF14659.6 EHT98582.1 - 0.14 12.4 0.1 0.25 11.6 0.1 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain DDE_3 PF13358.6 EHT98583.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHT98583.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHT98583.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHT98583.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHT98583.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHT98583.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHT98583.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHT98583.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 His_Phos_1 PF00300.22 EHT98584.1 - 2.8e-09 37.0 0.7 2.9e-08 33.6 0.7 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Sugar_tr PF00083.24 EHT98585.1 - 8.7e-31 107.3 25.4 2.3e-29 102.6 25.4 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EHT98585.1 - 1.5e-29 103.1 68.3 1.6e-25 89.8 38.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Peripla_BP_3 PF13377.6 EHT98586.1 - 4e-33 115.1 0.3 1e-32 113.7 0.1 1.7 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 EHT98586.1 - 3e-29 102.3 0.0 3.9e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 EHT98586.1 - 7e-16 58.6 0.0 1.5e-15 57.5 0.0 1.5 2 0 0 2 2 2 1 Periplasmic binding protein domain LacI PF00356.21 EHT98586.1 - 8.1e-14 51.1 0.7 1.4e-13 50.4 0.7 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family IU_nuc_hydro PF01156.19 EHT98587.1 - 2.9e-57 194.6 0.1 3.4e-57 194.3 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase MFS_1 PF07690.16 EHT98588.1 - 6.1e-47 160.3 68.9 4.7e-39 134.3 40.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EHT98588.1 - 1.3e-36 126.5 29.2 2.7e-27 95.7 8.5 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 EHT98588.1 - 3.1e-05 23.0 28.5 0.00013 21.0 9.4 2.4 2 1 1 3 3 3 2 MFS_1 like family MFS_5 PF05631.14 EHT98588.1 - 7.1e-05 21.9 1.7 0.0028 16.6 0.0 2.4 2 0 0 2 2 2 2 Sugar-tranasporters, 12 TM ATG22 PF11700.8 EHT98588.1 - 0.052 12.2 28.5 0.099 11.2 3.2 3.2 3 1 0 3 3 3 0 Vacuole effluxer Atg22 like OATP PF03137.20 EHT98588.1 - 0.91 7.7 8.8 0.055 11.8 1.1 2.6 2 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family tRNA_edit PF04073.15 EHT98589.1 - 3.4e-27 94.9 0.0 4.2e-27 94.7 0.0 1.0 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain DUF1858 PF08984.11 EHT98589.1 - 0.061 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1858) GGDEF PF00990.21 EHT98590.1 - 6.8e-46 155.9 0.2 9.6e-46 155.5 0.2 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain GGDEF_2 PF17853.1 EHT98590.1 - 0.0034 17.6 0.1 0.0061 16.8 0.1 1.4 1 0 0 1 1 1 1 GGDEF-like domain Enolase_N PF03952.16 EHT98590.1 - 0.18 12.0 0.1 0.95 9.6 0.0 2.0 1 1 1 2 2 2 0 Enolase, N-terminal domain S_4TM PF18159.1 EHT98590.1 - 0.43 9.8 6.5 0.084 12.2 2.0 1.9 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain DUF2645 PF10840.8 EHT98590.1 - 1.1 9.9 4.9 0.24 12.0 0.4 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2645) DUF1435 PF07256.12 EHT98591.1 - 5.1e-26 90.6 8.9 5.4e-26 90.5 8.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1435) Peptidase_M50B PF13398.6 EHT98591.1 - 0.055 13.1 5.2 0.058 13.0 5.2 1.0 1 0 0 1 1 1 0 Peptidase M50B-like DUF4131 PF13567.6 EHT98591.1 - 1.2 8.8 7.7 0.39 10.4 5.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) MTS PF05175.14 EHT98592.1 - 1.8e-60 203.3 0.0 2.6e-60 202.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain MTS_N PF08468.11 EHT98592.1 - 5.2e-56 189.1 0.0 1.6e-55 187.5 0.0 1.8 3 0 0 3 3 3 1 Methyltransferase small domain N-terminal Methyltransf_25 PF13649.6 EHT98592.1 - 5.8e-09 36.6 0.1 1.7e-08 35.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EHT98592.1 - 3.3e-08 33.5 0.0 8e-08 32.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EHT98592.1 - 4.2e-08 33.8 0.1 2.9e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EHT98592.1 - 0.00027 20.4 0.0 0.00046 19.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EHT98592.1 - 0.00044 20.9 0.0 0.001 19.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EHT98592.1 - 0.0017 18.3 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_10 PF05971.12 EHT98592.1 - 0.0026 17.1 0.0 0.0065 15.8 0.0 1.5 1 1 0 1 1 1 1 RNA methyltransferase NodS PF05401.11 EHT98592.1 - 0.0039 16.8 0.0 0.045 13.4 0.0 2.0 2 0 0 2 2 2 1 Nodulation protein S (NodS) Methyltransf_23 PF13489.6 EHT98592.1 - 0.0041 17.0 0.0 0.0076 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EHT98592.1 - 0.016 14.5 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_16 PF10294.9 EHT98592.1 - 0.031 14.0 0.0 0.087 12.5 0.0 1.6 2 0 0 2 2 2 0 Lysine methyltransferase UPF0020 PF01170.18 EHT98592.1 - 0.037 13.7 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 VirJ PF06057.11 EHT98592.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DNA_III_psi PF03603.13 EHT98593.1 - 1.5e-41 141.5 0.1 1.7e-41 141.4 0.1 1.0 1 0 0 1 1 1 1 DNA polymerase III psi subunit G2F PF07474.12 EHT98593.1 - 0.031 14.1 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 G2F domain CSTF_C PF14304.6 EHT98593.1 - 1.1 8.9 5.4 0.19 11.4 1.0 2.0 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal Acetyltransf_1 PF00583.25 EHT98594.1 - 2.5e-15 56.7 0.0 3e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EHT98594.1 - 1.2e-11 44.6 0.0 1.5e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EHT98594.1 - 6.6e-11 42.0 0.0 8.8e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EHT98594.1 - 2e-10 40.9 0.0 2.4e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 EHT98594.1 - 1.1e-05 25.2 0.0 1.3e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_8 PF13523.6 EHT98594.1 - 3.8e-05 23.4 0.0 6.1e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 EHT98594.1 - 5.7e-05 23.3 0.0 7.3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EHT98594.1 - 0.00031 20.9 0.0 0.00037 20.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EHT98594.1 - 0.015 15.4 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EHT98594.1 - 0.015 15.4 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 EHT98594.1 - 0.089 12.2 0.0 0.15 11.5 0.0 1.3 1 1 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_3 PF13302.7 EHT98594.1 - 0.12 13.1 0.0 0.13 13.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.6 EHT98594.1 - 0.12 11.8 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 HAD_2 PF13419.6 EHT98595.1 - 1.7e-22 80.3 0.0 3.7e-22 79.3 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EHT98595.1 - 1.1e-14 54.3 0.0 1.7e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EHT98595.1 - 1.8e-13 51.3 0.0 5e-13 49.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase SMP_2 PF10144.9 EHT98596.1 - 1.4e-66 223.1 0.2 1.8e-66 222.7 0.2 1.2 1 0 0 1 1 1 1 Bacterial virulence factor haemolysin TetR_C_16 PF17920.1 EHT98596.1 - 0.02 15.2 2.4 2.6 8.3 0.3 2.4 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain AI-2E_transport PF01594.16 EHT98596.1 - 0.097 11.8 1.7 0.12 11.5 0.1 1.7 2 0 0 2 2 2 0 AI-2E family transporter DUF5609 PF18429.1 EHT98597.1 - 2.9e-22 78.2 0.0 6.7e-22 77.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5609) HAD PF12710.7 EHT98597.1 - 2e-13 51.1 0.1 3.3e-13 50.5 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EHT98597.1 - 4.6e-13 49.9 1.0 8.7e-13 49.0 1.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EHT98597.1 - 1.8e-11 44.3 0.1 3.3e-10 40.2 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EHT98597.1 - 0.00029 20.5 0.0 0.00081 19.0 0.0 1.7 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase Put_Phosphatase PF06888.12 EHT98597.1 - 0.0014 18.0 0.0 0.038 13.4 0.0 2.1 2 0 0 2 2 2 1 Putative Phosphatase HAD_2 PF13419.6 EHT98597.1 - 0.05 13.7 0.0 0.57 10.3 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase ATPase PF06745.13 EHT98598.1 - 3.1e-16 59.4 0.1 1.3e-09 37.8 0.0 2.1 1 1 1 2 2 2 2 KaiC AAA_25 PF13481.6 EHT98598.1 - 3.5e-14 52.8 0.1 9.3e-14 51.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain Rubredoxin_2 PF18073.1 EHT98598.1 - 1.5e-12 47.0 6.0 2.5e-12 46.3 6.0 1.4 1 0 0 1 1 1 1 Rubredoxin metal binding domain ChlI PF13541.6 EHT98598.1 - 6.2e-10 39.0 0.1 1.5e-09 37.7 0.0 1.7 2 0 0 2 2 1 1 Subunit ChlI of Mg-chelatase DnaB_C PF03796.15 EHT98598.1 - 2.4e-07 30.3 0.5 0.00034 20.0 0.0 2.3 1 1 0 2 2 2 2 DnaB-like helicase C terminal domain Lon_C PF05362.13 EHT98598.1 - 5.4e-07 29.4 0.1 1.1e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain Rad51 PF08423.11 EHT98598.1 - 2.3e-05 23.8 0.3 0.001 18.4 0.3 2.2 1 1 0 1 1 1 1 Rad51 RecA PF00154.21 EHT98598.1 - 0.00068 19.2 0.1 0.0011 18.5 0.1 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA PF00004.29 EHT98598.1 - 0.00088 19.7 0.0 0.0017 18.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 EHT98598.1 - 0.00095 18.5 0.4 0.0058 15.9 0.0 1.9 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 EHT98598.1 - 0.0013 19.1 0.2 0.0065 16.9 0.1 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EHT98598.1 - 0.0018 18.6 0.0 0.0036 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain GvpD PF07088.11 EHT98598.1 - 0.0028 16.4 0.0 0.21 10.2 0.0 2.3 1 1 1 2 2 2 1 GvpD gas vesicle protein ABC_tran PF00005.27 EHT98598.1 - 0.0028 18.2 0.0 0.0055 17.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_24 PF13479.6 EHT98598.1 - 0.0036 17.0 0.0 0.0065 16.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 EHT98598.1 - 0.005 16.8 0.4 0.051 13.5 0.0 2.3 1 1 1 2 2 2 1 NTPase AAA_14 PF13173.6 EHT98598.1 - 0.0055 16.7 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EHT98598.1 - 0.0091 15.7 0.5 0.032 13.9 0.1 2.1 2 1 0 2 2 1 1 AAA domain T2SSE PF00437.20 EHT98598.1 - 0.01 14.9 0.1 0.04 13.0 0.0 2.0 2 1 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 EHT98598.1 - 0.016 14.5 0.1 0.03 13.6 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.14 EHT98598.1 - 0.03 14.3 0.0 0.065 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) cobW PF02492.19 EHT98598.1 - 0.036 13.7 0.0 0.062 12.9 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EHT98598.1 - 0.045 13.7 0.2 0.17 11.8 0.2 2.0 1 1 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 EHT98598.1 - 0.087 12.6 0.3 0.2 11.4 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EHT98598.1 - 0.098 12.7 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 EHT98598.1 - 0.19 11.5 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 EHT98599.1 - 4.1e-27 95.4 0.0 6.1e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain HTH_3 PF01381.22 EHT98599.1 - 6.4e-09 35.7 0.1 2.4e-08 33.9 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix HTH_31 PF13560.6 EHT98599.1 - 3e-07 30.7 0.0 6.2e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 EHT98599.1 - 5.5e-05 23.1 0.0 0.00049 20.1 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain CTP_transf_like PF01467.26 EHT98599.1 - 0.00043 20.5 0.1 0.004 17.4 0.0 2.4 2 1 0 2 2 2 1 Cytidylyltransferase-like Citrate_ly_lig PF08218.11 EHT98599.1 - 0.0037 17.0 0.0 0.011 15.4 0.0 1.9 2 0 0 2 2 2 1 Citrate lyase ligase C-terminal domain HTH_26 PF13443.6 EHT98599.1 - 0.018 15.5 0.0 0.032 14.7 0.0 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_37 PF13744.6 EHT98599.1 - 0.08 12.9 0.2 0.18 11.8 0.1 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain DUF4219 PF13961.6 EHT98599.1 - 0.082 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) DDE_Tnp_1_5 PF13737.6 EHT98600.1 - 4.4e-46 155.8 0.0 6e-45 152.2 0.0 2.2 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 EHT98600.1 - 7.1e-25 87.9 0.9 8.9e-25 87.6 0.9 1.1 1 0 0 1 1 1 1 Transposase DDE domain Trans_reg_C PF00486.28 EHT98601.1 - 5.3e-08 32.8 0.0 1e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Vps55 PF04133.14 EHT98602.1 - 0.035 14.0 0.2 1.9 8.5 0.0 2.2 2 0 0 2 2 2 0 Vacuolar protein sorting 55 FimA PF16970.5 EHT98603.1 - 1.4e-05 25.3 2.6 2.9e-05 24.3 2.6 1.6 1 1 0 1 1 1 1 Type-1 fimbrial protein, A DUF2574 PF10836.8 EHT98603.1 - 0.0059 16.4 0.3 0.012 15.5 0.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2574) HTH_Tnp_1 PF01527.20 EHT98604.1 - 2.6e-15 56.5 0.0 1.6e-14 53.9 0.0 2.2 2 1 0 2 2 2 1 Transposase HTH_23 PF13384.6 EHT98604.1 - 1.4e-06 27.9 0.0 0.017 14.9 0.0 2.3 2 0 0 2 2 2 2 Homeodomain-like domain HTH_28 PF13518.6 EHT98604.1 - 0.0034 17.5 0.0 0.66 10.2 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain MarR_2 PF12802.7 EHT98604.1 - 0.054 13.4 0.1 0.68 9.9 0.0 2.3 2 0 0 2 2 2 0 MarR family LZ_Tnp_IS481 PF13011.6 EHT98604.1 - 0.084 13.4 0.2 3.4 8.3 0.0 2.6 3 0 0 3 3 3 0 leucine-zipper of insertion element IS481 TnpB_IS66 PF05717.13 EHT98605.1 - 2.7e-05 24.0 0.0 2.9e-05 23.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHT98606.1 - 3.6e-98 328.5 3.2 7.1e-98 327.5 0.1 2.0 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT98606.1 - 1.3e-16 60.5 0.0 5.2e-16 58.6 0.0 2.1 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT98606.1 - 9.5e-15 54.7 2.3 2.2e-14 53.6 2.3 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT98606.1 - 2.6e-12 47.3 6.0 5.7e-12 46.2 6.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Troponin PF00992.20 EHT98606.1 - 0.0089 16.3 1.2 0.017 15.4 1.2 1.4 1 0 0 1 1 1 1 Troponin Shugoshin_N PF07558.11 EHT98606.1 - 0.026 14.4 0.3 0.076 12.9 0.3 1.8 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region FAM184 PF15665.5 EHT98606.1 - 0.026 14.3 5.1 0.042 13.6 5.1 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Csm1_N PF18504.1 EHT98606.1 - 0.068 13.5 2.9 0.15 12.4 1.1 2.3 1 1 1 2 2 2 0 Csm1 N-terminal domain LXG PF04740.12 EHT98606.1 - 0.13 12.0 0.9 0.52 10.0 0.5 2.0 1 1 1 2 2 2 0 LXG domain of WXG superfamily DUF1192 PF06698.11 EHT98606.1 - 0.16 12.0 2.9 1.6 8.8 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) HAUS-augmin3 PF14932.6 EHT98606.1 - 0.18 11.3 5.1 0.17 11.5 3.2 1.8 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Exonuc_VII_L PF02601.15 EHT98606.1 - 0.28 10.7 2.0 0.75 9.3 0.3 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit FUSC PF04632.12 EHT98606.1 - 0.54 8.7 10.5 0.038 12.5 4.7 1.9 2 0 0 2 2 2 0 Fusaric acid resistance protein family ERM PF00769.19 EHT98606.1 - 0.89 9.3 9.7 1.5 8.6 9.7 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DDE_3 PF13358.6 EHT98607.1 - 7e-23 81.0 0.0 9.2e-23 80.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.6 EHT98607.1 - 1.5e-06 27.8 4.9 2.7e-06 26.9 0.3 2.8 3 0 0 3 3 3 1 Winged helix-turn helix HTH_32 PF13565.6 EHT98607.1 - 0.0064 17.1 1.0 0.013 16.1 0.1 2.0 2 0 0 2 2 2 1 Homeodomain-like domain GTP_EFTU PF00009.27 EHT98608.1 - 6.2e-59 198.8 0.0 8.8e-59 198.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EHT98608.1 - 1e-33 116.0 0.0 2e-33 115.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EHT98608.1 - 2.1e-19 69.7 4.7 4.6e-19 68.6 4.7 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EHT98608.1 - 9.9e-05 22.4 0.0 0.0002 21.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 EHT98608.1 - 0.034 13.8 0.2 0.094 12.3 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Lsm_C PF14894.6 EHT98608.1 - 0.37 10.6 2.5 0.83 9.5 2.5 1.5 1 0 0 1 1 1 0 Lsm C-terminal SecE PF00584.20 EHT98609.1 - 1.4e-20 73.0 0.9 1.4e-20 73.0 0.9 2.7 3 0 0 3 3 3 1 SecE/Sec61-gamma subunits of protein translocation complex DUF1129 PF06570.11 EHT98609.1 - 0.18 11.2 2.7 0.27 10.7 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) EptA_B_N PF08019.12 EHT98609.1 - 0.29 11.0 6.4 0.19 11.6 2.2 2.4 1 1 1 2 2 2 0 Phosphoethanolamine transferase EptA/EptB Trp_oprn_chp PF09534.10 EHT98609.1 - 0.7 9.7 10.6 0.83 9.4 10.6 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SLATT_3 PF18184.1 EHT98609.1 - 9.3 6.4 8.7 3.9 7.6 2.7 2.1 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 3 NusG PF02357.19 EHT98610.1 - 2e-27 95.5 0.0 2.8e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 Transcription termination factor nusG KOW PF00467.29 EHT98610.1 - 1.1e-08 34.7 0.0 6.1e-08 32.4 0.1 2.2 2 0 0 2 2 2 1 KOW motif Ribosomal_L11_N PF03946.14 EHT98611.1 - 2.9e-31 107.1 0.2 4.7e-31 106.4 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EHT98611.1 - 6.9e-27 93.8 2.1 1e-26 93.2 2.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain DUF3140 PF11338.8 EHT98611.1 - 0.02 15.3 0.5 0.063 13.7 0.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3140) Ribosomal_L1 PF00687.21 EHT98612.1 - 2.2e-52 177.8 0.2 2.8e-52 177.4 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_L10 PF00466.20 EHT98613.1 - 2.9e-25 88.3 0.0 4.1e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_L12 PF00542.19 EHT98614.1 - 1.3e-25 89.6 9.2 1.3e-25 89.6 9.2 1.7 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 EHT98614.1 - 2.1e-17 62.6 11.7 2.1e-17 62.6 11.7 2.9 3 1 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain Esterase_phd PF10503.9 EHT98614.1 - 0.13 11.7 4.6 0.29 10.6 4.6 1.6 1 1 0 1 1 1 0 Esterase PHB depolymerase DUF2279 PF10043.9 EHT98614.1 - 0.15 12.8 0.4 0.37 11.6 0.1 1.8 2 1 0 2 2 2 0 Predicted periplasmic lipoprotein (DUF2279) DUF2805 PF10985.8 EHT98614.1 - 0.17 12.3 0.0 0.52 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) RNA_pol_Rpb2_6 PF00562.28 EHT98615.1 - 4.9e-161 536.2 1.0 6.4e-160 532.5 0.3 2.5 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EHT98615.1 - 8.6e-58 195.2 0.0 2.1e-57 194.0 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 EHT98615.1 - 4.1e-31 107.0 0.0 9e-31 105.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 EHT98615.1 - 6.4e-28 97.0 0.1 2e-27 95.4 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 EHT98615.1 - 1.4e-26 93.4 1.0 2.7e-16 59.8 0.1 3.2 3 0 0 3 3 3 2 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_45 PF10385.9 EHT98615.1 - 1.9e-25 88.9 0.1 1.7e-24 85.8 0.1 2.6 2 0 0 2 2 2 1 RNA polymerase beta subunit external 1 domain Spc7 PF08317.11 EHT98615.1 - 1.5 7.6 6.9 3.6 6.4 6.9 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein RNA_pol_Rpb1_1 PF04997.12 EHT98616.1 - 2.9e-90 302.8 0.0 4.6e-90 302.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EHT98616.1 - 1.6e-78 263.8 0.1 2.7e-78 263.1 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EHT98616.1 - 1.2e-37 129.7 0.1 3.6e-27 95.6 0.0 2.8 2 1 1 3 3 3 2 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EHT98616.1 - 3.4e-26 92.0 0.0 8.7e-26 90.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EHT98616.1 - 5.5e-19 68.1 0.2 1.4e-18 66.8 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Apocytochr_F_C PF01333.19 EHT98616.1 - 0.094 12.8 0.1 4.9 7.2 0.0 2.7 2 0 0 2 2 2 0 Apocytochrome F, C-terminal DUF1127 PF06568.11 EHT98617.1 - 6.8e-13 48.1 1.3 8.2e-13 47.8 1.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1127) Aminotran_1_2 PF00155.21 EHT98618.1 - 4.5e-38 131.4 0.0 6.1e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 EHT98618.1 - 3.2e-14 52.3 2.2 5.4e-14 51.6 0.2 2.5 3 0 0 3 3 3 1 Bacterial regulatory proteins, gntR family HTH_41 PF14502.6 EHT98618.1 - 1.2e-05 24.9 0.0 2.5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Aminotran_MocR PF12897.7 EHT98618.1 - 0.007 15.2 0.0 0.013 14.3 0.0 1.4 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase TMP-TENI PF02581.17 EHT98619.1 - 1.4e-55 187.4 0.1 1.8e-55 187.1 0.1 1.0 1 0 0 1 1 1 1 Thiamine monophosphate synthase QRPTase_C PF01729.19 EHT98619.1 - 0.00076 19.3 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain ThiC_Rad_SAM PF01964.18 EHT98620.1 - 8.9e-199 660.5 0.0 1.2e-198 660.1 0.0 1.2 1 0 0 1 1 1 1 Radical SAM ThiC family ThiC-associated PF13667.6 EHT98620.1 - 1.1e-32 111.7 0.1 2.7e-32 110.4 0.1 1.8 1 0 0 1 1 1 1 ThiC-associated domain Rsd_AlgQ PF04353.13 EHT98621.1 - 2.1e-48 164.1 0.1 2.5e-48 163.9 0.1 1.0 1 0 0 1 1 1 1 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ FragX_IP PF05994.11 EHT98621.1 - 0.1 10.6 0.0 0.12 10.4 0.0 1.0 1 0 0 1 1 1 0 Cytoplasmic Fragile-X interacting family NUDIX PF00293.28 EHT98622.1 - 6.3e-16 58.6 0.0 1.1e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 EHT98622.1 - 1.7e-07 30.7 11.8 3.6e-07 29.7 11.8 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain URO-D PF01208.17 EHT98623.1 - 3.4e-142 473.7 0.0 3.9e-142 473.5 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Endonuclease_5 PF04493.14 EHT98624.1 - 1e-73 247.3 0.0 1.2e-73 247.0 0.0 1.0 1 0 0 1 1 1 1 Endonuclease V UvrC_HhH_N PF08459.11 EHT98624.1 - 0.052 13.5 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal DUF99 PF01949.16 EHT98624.1 - 0.089 12.2 0.0 0.2 11.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF99 DUF416 PF04222.12 EHT98625.1 - 2.7e-81 271.5 0.1 3e-81 271.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF416) Bac_DNA_binding PF00216.21 EHT98626.1 - 6e-33 112.9 1.1 6.6e-33 112.8 1.1 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 EHT98626.1 - 4.9e-08 33.1 0.1 5.1e-08 33.0 0.1 1.0 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_bac_2 PF18175.1 EHT98626.1 - 2.3e-06 27.3 0.1 3.2e-06 26.9 0.1 1.1 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 HU-CCDC81_euk_2 PF18289.1 EHT98626.1 - 0.0011 19.1 0.0 0.0016 18.6 0.0 1.2 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 HU-CCDC81_euk_1 PF14908.6 EHT98626.1 - 0.003 17.7 0.0 0.0032 17.6 0.0 1.1 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 DUF2267 PF10025.9 EHT98626.1 - 0.087 13.1 0.1 0.14 12.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) NA37 PF04245.13 EHT98626.1 - 0.092 12.2 0.1 0.094 12.2 0.1 1.1 1 0 0 1 1 1 0 37-kD nucleoid-associated bacterial protein DUF1481 PF07356.12 EHT98627.1 - 7.1e-62 208.5 0.1 8e-62 208.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1481) PSD3 PF07626.11 EHT98627.1 - 0.071 13.6 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1587) GARS_A PF01071.19 EHT98628.1 - 1.9e-83 279.0 0.1 2.5e-83 278.7 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 EHT98628.1 - 1e-35 122.4 0.1 2e-35 121.4 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 EHT98628.1 - 1.3e-27 95.9 0.3 1.9e-26 92.1 0.1 2.4 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp_3 PF02655.14 EHT98628.1 - 5.4e-06 26.6 0.0 1e-05 25.6 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 EHT98628.1 - 1.3e-05 24.8 0.0 2.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 EHT98628.1 - 0.00065 19.3 0.0 0.001 18.7 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 EHT98628.1 - 0.0017 17.9 0.0 0.0048 16.5 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 EHT98628.1 - 0.035 13.7 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 RimK-like ATP-grasp domain AICARFT_IMPCHas PF01808.18 EHT98629.1 - 7.5e-119 396.6 6.0 9.3e-119 396.2 6.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 EHT98629.1 - 1.2e-30 105.6 0.0 3e-30 104.3 0.0 1.8 1 0 0 1 1 1 1 MGS-like domain CoA_binding_2 PF13380.6 EHT98629.1 - 0.66 10.5 5.9 3.5 8.1 0.0 3.7 3 2 0 3 3 3 0 CoA binding domain HTH_Tnp_1 PF01527.20 EHT98630.1 - 2.6e-15 56.5 0.0 1.6e-14 53.9 0.0 2.2 2 1 0 2 2 2 1 Transposase HTH_23 PF13384.6 EHT98630.1 - 1.4e-06 27.9 0.0 0.017 14.9 0.0 2.3 2 0 0 2 2 2 2 Homeodomain-like domain HTH_28 PF13518.6 EHT98630.1 - 0.0034 17.5 0.0 0.66 10.2 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain MarR_2 PF12802.7 EHT98630.1 - 0.054 13.4 0.1 0.68 9.9 0.0 2.3 2 0 0 2 2 2 0 MarR family LZ_Tnp_IS481 PF13011.6 EHT98630.1 - 0.084 13.4 0.2 3.4 8.3 0.0 2.6 3 0 0 3 3 3 0 leucine-zipper of insertion element IS481 TnpB_IS66 PF05717.13 EHT98631.1 - 2.7e-05 24.0 0.0 2.9e-05 23.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHT98632.1 - 8e-97 324.1 5.0 1.6e-96 323.1 0.1 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT98632.1 - 5e-17 61.8 0.0 2.1e-16 59.8 0.0 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT98632.1 - 8.6e-15 54.9 1.3 1.9e-14 53.8 1.3 1.6 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT98632.1 - 1.6e-11 44.8 9.6 3.5e-11 43.7 9.6 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHT98632.1 - 0.016 15.0 6.4 0.027 14.3 6.4 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Exonuc_VII_L PF02601.15 EHT98632.1 - 0.021 14.4 2.9 0.039 13.5 0.6 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit Phage_HK97_TLTM PF06120.11 EHT98632.1 - 0.021 14.0 1.7 0.042 13.0 1.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHT98632.1 - 0.022 15.1 4.3 0.091 13.1 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Tho2 PF11262.8 EHT98632.1 - 0.055 12.7 0.5 0.094 11.9 0.5 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Troponin PF00992.20 EHT98632.1 - 0.059 13.7 3.0 0.11 12.8 3.0 1.4 1 0 0 1 1 1 0 Troponin LXG PF04740.12 EHT98632.1 - 0.11 12.2 2.6 0.33 10.6 0.4 2.2 1 1 1 2 2 2 0 LXG domain of WXG superfamily UME PF08064.13 EHT98632.1 - 0.13 12.2 0.6 16 5.5 0.0 3.1 2 1 1 3 3 3 0 UME (NUC010) domain ERM PF00769.19 EHT98632.1 - 0.16 11.8 10.8 0.26 11.1 10.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HalX PF08663.10 EHT98632.1 - 0.21 11.9 3.1 0.59 10.5 3.1 1.7 1 0 0 1 1 1 0 HalX domain DHR10 PF18595.1 EHT98632.1 - 0.36 10.9 10.9 0.66 10.0 10.9 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF1192 PF06698.11 EHT98632.1 - 0.45 10.6 5.3 3.4 7.8 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) FUSC PF04632.12 EHT98632.1 - 0.82 8.1 12.5 0.056 12.0 6.9 1.7 2 0 0 2 2 2 0 Fusaric acid resistance protein family TMPIT PF07851.13 EHT98632.1 - 1.1 8.4 3.1 1.7 7.8 3.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein OmpH PF03938.14 EHT98632.1 - 3.2 8.1 7.9 6.7 7.0 7.9 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HAUS-augmin3 PF14932.6 EHT98632.1 - 6.5 6.3 10.0 6.1 6.3 7.9 1.9 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 MurB_C PF02873.16 EHT98633.1 - 6.6e-38 129.5 0.0 1e-37 128.9 0.0 1.3 1 0 0 1 1 1 1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain FAD_binding_4 PF01565.23 EHT98633.1 - 5.1e-23 81.3 0.1 8.7e-23 80.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain BPL_LplA_LipB PF03099.19 EHT98634.1 - 2e-23 82.8 0.0 2.8e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 EHT98634.1 - 8.4e-14 51.2 0.1 1.9e-13 50.1 0.1 1.6 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain HTH_11 PF08279.12 EHT98634.1 - 6.3e-12 45.3 0.0 1.3e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 HTH domain BPL_LplA_LipB_2 PF16917.5 EHT98634.1 - 0.017 14.7 0.4 0.025 14.1 0.4 1.2 1 0 0 1 1 1 0 Biotin/lipoate A/B protein ligase family HTH_20 PF12840.7 EHT98634.1 - 0.037 14.1 0.0 0.089 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 EHT98634.1 - 0.048 13.6 0.1 0.87 9.6 0.0 2.5 2 1 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_24 PF13412.6 EHT98634.1 - 0.054 13.1 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 EHT98634.1 - 0.062 13.2 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family DUF1323 PF07037.11 EHT98634.1 - 0.11 12.9 0.1 24 5.3 0.0 2.3 2 0 0 2 2 2 0 Putative transcription regulator (DUF1323) Mga PF05043.13 EHT98634.1 - 0.19 12.3 0.0 0.34 11.5 0.0 1.4 1 0 0 1 1 1 0 Mga helix-turn-helix domain PRK PF00485.18 EHT98635.1 - 1.1e-15 57.9 0.0 1.7e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.6 EHT98635.1 - 0.074 13.3 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain DDE_Tnp_IS66 PF03050.14 EHT98636.1 - 4.1e-58 197.1 5.4 1.2e-57 195.6 0.1 2.1 2 0 0 2 2 2 1 Transposase IS66 family zf-IS66 PF13005.7 EHT98636.1 - 9.3e-15 54.8 1.5 2.1e-14 53.6 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT98636.1 - 4.9e-11 43.3 9.0 1.1e-10 42.2 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Exonuc_VII_L PF02601.15 EHT98636.1 - 0.015 14.8 1.0 0.021 14.4 1.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phage_HK97_TLTM PF06120.11 EHT98636.1 - 0.018 14.2 0.7 0.033 13.4 0.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein FUSC PF04632.12 EHT98636.1 - 0.043 12.4 7.8 0.056 12.0 7.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Csm1_N PF18504.1 EHT98636.1 - 0.079 13.3 3.9 0.58 10.5 0.3 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain DHR10 PF18595.1 EHT98636.1 - 0.1 12.6 10.2 0.17 11.9 10.2 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Tho2 PF11262.8 EHT98636.1 - 0.11 11.6 0.4 0.17 11.1 0.4 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 ERM PF00769.19 EHT98636.1 - 0.14 12.0 10.1 0.2 11.4 10.1 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family LXG PF04740.12 EHT98636.1 - 0.14 11.8 2.6 0.49 10.1 0.3 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily DUF5347 PF17282.2 EHT98636.1 - 0.15 12.4 0.7 5 7.5 0.2 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5347) Zn-ribbon_8 PF09723.10 EHT98636.1 - 0.16 12.1 1.7 0.66 10.1 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain LCE6A PF15858.5 EHT98636.1 - 0.22 12.3 1.9 0.88 10.4 2.3 1.8 2 0 0 2 2 1 0 Late cornified envelope protein 6A family HHH_8 PF14716.6 EHT98636.1 - 0.24 11.8 3.1 0.74 10.2 3.1 1.9 1 1 0 1 1 1 0 Helix-hairpin-helix domain FAM184 PF15665.5 EHT98636.1 - 0.28 10.9 7.3 0.43 10.3 7.3 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B TSNAXIP1_N PF15739.5 EHT98636.1 - 0.3 11.5 3.2 0.56 10.6 3.2 1.4 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus CREPT PF16566.5 EHT98636.1 - 0.31 11.2 5.2 0.56 10.4 5.2 1.3 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour PCRF PF03462.18 EHT98636.1 - 0.39 10.6 3.0 0.61 9.9 3.0 1.2 1 0 0 1 1 1 0 PCRF domain TMPIT PF07851.13 EHT98636.1 - 0.46 9.7 2.7 0.65 9.2 2.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHT98636.1 - 1.4 8.4 7.4 3.3 7.2 7.5 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 SlyX PF04102.12 EHT98636.1 - 6.1 7.6 9.1 9.4 6.9 2.0 2.8 1 1 1 2 2 2 0 SlyX OmpH PF03938.14 EHT98636.1 - 6.8 7.0 8.5 10 6.4 8.5 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TnpB_IS66 PF05717.13 EHT98637.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHT98638.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT98638.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT98638.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT98638.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix HemY_N PF07219.13 EHT98639.1 - 6.9e-33 113.1 2.7 6.9e-33 113.1 2.7 3.8 4 2 1 5 5 4 1 HemY protein N-terminus TPR_7 PF13176.6 EHT98639.1 - 9.8e-06 25.3 0.9 0.026 14.5 0.3 3.4 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EHT98639.1 - 1e-05 25.9 30.2 0.015 16.1 2.9 7.3 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 EHT98639.1 - 4e-05 23.4 0.3 4e-05 23.4 0.3 4.8 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EHT98639.1 - 0.00048 19.8 1.0 0.0095 15.7 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EHT98639.1 - 0.002 18.7 7.0 0.002 18.7 7.0 4.3 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EHT98639.1 - 0.0035 17.8 20.9 0.06 13.9 1.9 5.0 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 EHT98639.1 - 0.0076 16.4 17.6 0.011 15.9 2.0 4.1 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EHT98639.1 - 0.03 14.6 1.5 0.03 14.6 1.5 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat LPG_synthase_TM PF03706.13 EHT98639.1 - 0.041 13.4 1.6 0.07 12.6 1.6 1.4 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region TPR_11 PF13414.6 EHT98639.1 - 0.043 13.5 0.3 0.11 12.2 0.3 1.8 1 0 0 1 1 1 0 TPR repeat NrsF PF06532.11 EHT98639.1 - 0.076 12.7 1.2 0.13 12.0 1.2 1.4 1 0 0 1 1 1 0 Negative regulator of sigma F OppC_N PF12911.7 EHT98639.1 - 0.077 13.0 4.6 4.8 7.2 0.8 2.5 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF4834 PF16118.5 EHT98639.1 - 0.1 13.6 1.8 0.19 12.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) BPD_transp_1 PF00528.22 EHT98639.1 - 0.12 12.0 5.2 0.19 11.4 5.2 1.3 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component Wzy_C_2 PF11846.8 EHT98639.1 - 3.4 7.6 9.5 14 5.5 0.4 3.2 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal TPR_6 PF13174.6 EHT98639.1 - 4.5 8.1 10.8 0.61 10.8 0.2 4.1 5 0 0 5 5 3 0 Tetratricopeptide repeat HemX PF04375.14 EHT98640.1 - 5.1e-134 446.8 29.1 6e-134 446.6 29.1 1.0 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase Tweety PF04906.13 EHT98640.1 - 0.00072 18.3 0.5 0.0015 17.3 0.5 1.5 1 0 0 1 1 1 1 Tweety DUF1664 PF07889.12 EHT98640.1 - 0.0011 18.9 6.9 0.0016 18.5 4.7 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) DUF1043 PF06295.12 EHT98640.1 - 0.0031 17.5 4.3 0.0095 15.9 4.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1043) Sigma70_ner PF04546.13 EHT98640.1 - 0.016 15.1 6.3 0.017 15.0 4.7 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region RskA PF10099.9 EHT98640.1 - 0.039 14.3 11.9 0.026 14.8 8.4 2.1 1 1 1 2 2 2 0 Anti-sigma-K factor rskA VIT1 PF01988.19 EHT98640.1 - 0.15 11.9 4.9 0.057 13.3 1.6 1.8 2 0 0 2 2 2 0 VIT family Cytadhesin_P30 PF07271.11 EHT98640.1 - 0.17 11.4 1.6 0.25 10.8 1.6 1.2 1 0 0 1 1 1 0 Cytadhesin P30/P32 DUF3810 PF12725.7 EHT98640.1 - 0.24 10.7 1.7 0.5 9.7 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Utp12 PF04003.12 EHT98640.1 - 0.35 11.2 3.4 0.39 11.0 0.6 2.6 4 0 0 4 4 3 0 Dip2/Utp12 Family TnpV PF14198.6 EHT98640.1 - 0.39 10.7 4.5 1.1 9.3 4.5 1.7 1 0 0 1 1 1 0 Transposon-encoded protein TnpV DUF3819 PF12842.7 EHT98640.1 - 0.49 10.3 7.6 0.12 12.3 3.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3819) DUF948 PF06103.11 EHT98640.1 - 1 9.6 5.8 0.72 10.1 2.2 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4407 PF14362.6 EHT98640.1 - 1.6 8.0 12.9 0.093 12.1 7.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) BshC PF10079.9 EHT98640.1 - 2.3 6.9 9.6 0.53 9.0 5.9 1.6 2 0 0 2 2 2 0 Bacillithiol biosynthesis BshC DUF4366 PF14283.6 EHT98640.1 - 2.5 8.1 5.6 0.59 10.2 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) Baculo_PEP_C PF04513.12 EHT98640.1 - 3.1 7.8 18.9 0.064 13.3 4.8 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMPIT PF07851.13 EHT98640.1 - 3.9 6.6 10.0 0.72 9.0 6.3 1.6 2 0 0 2 2 2 0 TMPIT-like protein Matrilin_ccoil PF10393.9 EHT98640.1 - 4.6 7.2 11.1 23 4.9 0.2 3.4 2 1 1 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Fzo_mitofusin PF04799.13 EHT98640.1 - 7.1 6.2 12.2 1.3 8.5 7.7 2.0 3 0 0 3 3 3 0 fzo-like conserved region FUSC PF04632.12 EHT98640.1 - 8.7 4.7 14.2 0.24 9.9 3.9 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family HEM4 PF02602.15 EHT98641.1 - 5.4e-37 127.4 0.0 6.1e-37 127.2 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD CUE PF02845.16 EHT98641.1 - 0.011 15.4 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 CUE domain Porphobil_deam PF01379.20 EHT98642.1 - 2.3e-81 272.2 0.0 3.5e-81 271.6 0.0 1.3 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EHT98642.1 - 4.9e-23 81.3 0.1 8.9e-23 80.5 0.1 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Adenylate_cycl PF01295.18 EHT98643.1 - 2e-255 849.1 0.0 2.5e-255 848.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate cyclase, class-I Adenyl_cycl_N PF12633.7 EHT98643.1 - 2.4e-79 265.9 0.0 7e-78 261.1 0.0 2.2 2 0 0 2 2 2 1 Adenylate cyclase NT domain FCD PF07729.12 EHT98643.1 - 0.074 13.5 0.1 1.8 9.0 0.1 2.6 2 0 0 2 2 2 0 FCD domain LPAM_2 PF13627.6 EHT98644.1 - 5.3e-09 35.7 6.7 7.9e-09 35.1 6.7 1.3 1 0 0 1 1 1 1 Prokaryotic lipoprotein-attachment site PA26 PF04636.13 EHT98644.1 - 0.15 11.0 0.0 0.15 11.0 0.0 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DAP_epimerase PF01678.19 EHT98645.1 - 1.5e-67 225.3 0.1 1.3e-34 118.9 0.0 2.0 2 0 0 2 2 2 2 Diaminopimelate epimerase PhzC-PhzF PF02567.16 EHT98645.1 - 0.00043 19.8 0.0 0.00059 19.4 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.11 EHT98645.1 - 0.03 13.4 0.1 3 6.8 0.1 2.2 2 0 0 2 2 2 0 Proline racemase DUF484 PF04340.12 EHT98646.1 - 4.5e-79 265.3 2.7 5.2e-79 265.1 2.7 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF484 Phage_integrase PF00589.22 EHT98647.1 - 5.8e-54 182.5 0.0 9.3e-54 181.8 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 EHT98647.1 - 1e-22 80.2 1.4 2e-22 79.3 0.4 1.9 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 EHT98647.1 - 0.012 16.0 0.0 1 9.7 0.0 2.4 1 1 1 2 2 2 0 Phage integrase SAM-like domain DUF3435 PF11917.8 EHT98647.1 - 0.02 13.9 0.1 0.034 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Phage_int_SAM_4 PF13495.6 EHT98647.1 - 0.033 14.7 0.0 0.23 12.0 0.0 2.2 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain HAD_2 PF13419.6 EHT98648.1 - 1.7e-13 51.0 0.0 5.5e-13 49.4 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EHT98648.1 - 4.8e-13 49.9 0.1 7.1e-13 49.3 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EHT98648.1 - 6.9e-10 38.9 0.0 3.2e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like Methyltransf_24 PF13578.6 EHT98648.1 - 0.026 15.5 0.6 0.52 11.4 0.2 2.2 1 1 1 2 2 2 0 Methyltransferase domain PGP_phosphatase PF09419.10 EHT98648.1 - 0.027 14.1 0.3 2.7 7.6 0.0 2.9 3 1 0 3 3 3 0 Mitochondrial PGP phosphatase DUF1338 PF07063.13 EHT98648.1 - 0.071 12.3 0.1 0.097 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1338) UvrD-helicase PF00580.21 EHT98649.1 - 9.9e-76 255.3 0.0 2.4e-75 254.0 0.0 1.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 EHT98649.1 - 7.6e-75 252.5 0.0 4.2e-74 250.0 0.0 1.9 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EHT98649.1 - 1.1e-32 113.4 0.0 3.2e-32 111.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EHT98649.1 - 3.9e-10 39.8 0.2 0.0012 18.6 0.0 2.9 3 0 0 3 3 3 2 AAA domain UvrD_C_2 PF13538.6 EHT98649.1 - 2.3e-09 36.9 0.0 5e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EHT98649.1 - 0.0023 17.7 0.0 3.8 7.2 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 EHT98649.1 - 0.0024 17.4 0.0 0.024 14.1 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_11 PF13086.6 EHT98649.1 - 0.014 15.2 0.0 0.56 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Exonuc_V_gamma PF04257.14 EHT98649.1 - 0.026 12.8 1.9 0.024 12.9 0.6 1.5 2 0 0 2 2 2 0 Exodeoxyribonuclease V, gamma subunit CorA PF01544.18 EHT98650.1 - 1.2e-55 188.9 0.2 1.4e-55 188.7 0.2 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein PARP_reg PF02877.14 EHT98650.1 - 0.07 13.2 0.6 10 6.2 0.1 2.5 3 0 0 3 3 3 0 Poly(ADP-ribose) polymerase, regulatory domain DDE_Tnp_1_5 PF13737.6 EHT98651.1 - 1.2e-44 151.2 0.0 3.1e-44 149.9 0.0 1.7 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 EHT98651.1 - 1.9e-24 86.5 1.0 2.3e-24 86.2 1.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain HxlR PF01638.17 EHT98652.1 - 1.5e-26 92.1 0.1 1.9e-26 91.7 0.1 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix PadR PF03551.14 EHT98652.1 - 0.00097 19.1 0.1 0.0014 18.5 0.1 1.4 1 1 0 1 1 1 1 Transcriptional regulator PadR-like family MarR_2 PF12802.7 EHT98652.1 - 0.0053 16.6 0.1 0.0098 15.8 0.1 1.4 1 0 0 1 1 1 1 MarR family HTH_34 PF13601.6 EHT98652.1 - 0.011 15.9 0.0 0.014 15.6 0.0 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain Replic_Relax PF13814.6 EHT98652.1 - 0.015 15.4 0.2 0.017 15.2 0.2 1.1 1 0 0 1 1 1 0 Replication-relaxation DUF3116 PF11313.8 EHT98652.1 - 0.056 13.3 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3116) HTH_20 PF12840.7 EHT98652.1 - 0.071 13.2 0.8 0.12 12.4 0.7 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain MarR PF01047.22 EHT98652.1 - 0.092 12.7 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 MarR family SnoaL PF07366.12 EHT98653.1 - 2.5e-16 59.6 1.5 3e-15 56.1 1.5 2.0 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 EHT98653.1 - 1.1e-15 58.1 0.2 1.4e-15 57.7 0.2 1.2 1 0 0 1 1 1 1 SnoaL-like domain LEH PF07858.12 EHT98653.1 - 1.8e-05 24.8 0.1 2.7e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Limonene-1,2-epoxide hydrolase catalytic domain Clathrin_H_link PF13838.6 EHT98653.1 - 0.0079 16.1 0.5 0.023 14.6 0.5 1.8 1 1 0 1 1 1 1 Clathrin-H-link DsrC PF04358.13 EHT98653.1 - 0.082 13.4 0.0 0.76 10.3 0.0 2.1 2 0 0 2 2 2 0 DsrC like protein DUF4019 PF13211.6 EHT98653.1 - 0.15 12.5 0.2 2.4 8.6 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4019) 4HBT PF03061.22 EHT98654.1 - 7.1e-18 64.7 0.3 9.5e-18 64.3 0.3 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 EHT98654.1 - 9.1e-07 29.4 0.6 1.3e-06 28.9 0.6 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.6 EHT98654.1 - 0.0015 18.6 0.0 0.014 15.5 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4442) PLA1 PF02253.15 EHT98655.1 - 8.4e-96 320.5 7.8 9.9e-96 320.3 7.8 1.0 1 0 0 1 1 1 1 Phospholipase A1 RQC PF09382.10 EHT98656.1 - 4.3e-37 126.4 0.0 3.4e-36 123.5 0.0 2.3 2 0 0 2 2 2 1 RQC domain Helicase_C PF00271.31 EHT98656.1 - 2.8e-26 92.0 0.0 3.1e-19 69.4 0.0 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain HRDC PF00570.23 EHT98656.1 - 1e-23 83.1 0.0 2.3e-23 81.9 0.0 1.7 1 0 0 1 1 1 1 HRDC domain DEAD PF00270.29 EHT98656.1 - 6.9e-22 78.0 0.0 1.3e-20 73.9 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 EHT98656.1 - 1.4e-15 57.8 0.2 3.6e-15 56.4 0.2 1.8 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 EHT98656.1 - 0.021 14.8 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit LysE PF01810.18 EHT98657.1 - 4.5e-51 173.1 11.4 5.2e-51 172.9 11.4 1.0 1 0 0 1 1 1 1 LysE type translocator TerC PF03741.16 EHT98657.1 - 4.8e-05 23.1 3.2 4.8e-05 23.1 3.2 2.1 2 1 0 2 2 2 1 Integral membrane protein TerC family OFeT_1 PF16955.5 EHT98657.1 - 0.014 15.1 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron uptake permease, iron-lead transporter DUF3180 PF11377.8 EHT98657.1 - 0.032 14.4 2.3 0.032 14.4 2.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) SUR7 PF06687.12 EHT98657.1 - 0.14 11.8 2.6 0.21 11.2 2.6 1.3 1 0 0 1 1 1 0 SUR7/PalI family Peptidase_U4 PF03419.13 EHT98657.1 - 0.22 10.8 4.8 0.036 13.4 0.9 1.6 2 0 0 2 2 2 0 Sporulation factor SpoIIGA RseC_MucC PF04246.12 EHT98657.1 - 0.36 10.8 3.7 0.21 11.5 0.6 2.1 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF4131 PF13567.6 EHT98657.1 - 7.1 6.3 8.9 0.57 9.8 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4064 PF13273.6 EHT98657.1 - 7.7 6.8 11.6 59 4.0 2.9 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) LysE PF01810.18 EHT98658.1 - 1.1e-41 142.4 13.6 1.3e-41 142.2 13.6 1.0 1 0 0 1 1 1 1 LysE type translocator Hydrolase_4 PF12146.8 EHT98659.1 - 8.1e-56 189.0 0.2 9.7e-56 188.7 0.2 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EHT98659.1 - 7.8e-28 97.8 0.1 1e-27 97.4 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EHT98659.1 - 1.5e-10 42.1 5.7 2.2e-10 41.5 5.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EHT98659.1 - 0.00012 21.6 0.0 0.11 11.9 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_3 PF08282.12 EHT98660.1 - 4.5e-42 144.5 0.0 5.1e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EHT98660.1 - 7e-12 45.4 0.0 2.4e-08 33.8 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase_6 PF13344.6 EHT98660.1 - 4.7e-05 23.4 0.0 0.00023 21.2 0.0 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase UPF0181 PF03701.14 EHT98660.1 - 0.0025 17.4 0.3 0.75 9.5 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0181) Trehalose_PPase PF02358.16 EHT98660.1 - 0.034 13.3 0.0 2 7.5 0.0 2.1 2 0 0 2 2 2 0 Trehalose-phosphatase Hydrolase PF00702.26 EHT98660.1 - 0.16 12.2 0.1 0.82 9.9 0.0 2.1 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase HTH_Tnp_1 PF01527.20 EHT98661.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT98661.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT98661.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT98661.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHT98662.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHT98663.1 - 1.1e-97 326.9 4.0 3.8e-97 325.1 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT98663.1 - 3.2e-16 59.2 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT98663.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT98663.1 - 1.2e-11 45.2 9.0 2.6e-11 44.1 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHT98663.1 - 0.017 14.9 6.4 0.027 14.3 6.4 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Phage_HK97_TLTM PF06120.11 EHT98663.1 - 0.022 14.0 1.7 0.042 13.0 1.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHT98663.1 - 0.022 15.1 4.3 0.091 13.1 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain FUSC PF04632.12 EHT98663.1 - 0.038 12.6 6.8 0.06 11.9 6.8 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 EHT98663.1 - 0.04 13.5 2.2 0.047 13.2 0.8 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Tho2 PF11262.8 EHT98663.1 - 0.057 12.6 0.5 0.094 11.9 0.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Troponin PF00992.20 EHT98663.1 - 0.062 13.6 3.0 0.11 12.8 3.0 1.3 1 0 0 1 1 1 0 Troponin LXG PF04740.12 EHT98663.1 - 0.11 12.3 2.5 0.32 10.7 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily UME PF08064.13 EHT98663.1 - 0.15 12.0 0.5 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain ERM PF00769.19 EHT98663.1 - 0.16 11.8 10.8 0.26 11.1 10.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HalX PF08663.10 EHT98663.1 - 0.23 11.8 3.1 0.59 10.5 3.1 1.7 1 0 0 1 1 1 0 HalX domain DHR10 PF18595.1 EHT98663.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Zn-ribbon_8 PF09723.10 EHT98663.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF1192 PF06698.11 EHT98663.1 - 0.53 10.4 5.3 3.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHT98663.1 - 1.1 8.4 3.1 1.7 7.8 3.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHT98663.1 - 2.8 7.4 7.9 6.1 6.3 7.9 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHT98663.1 - 3.3 8.1 7.9 6.7 7.0 7.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 EHT98663.1 - 7.2 7.3 8.7 7.7 7.2 1.0 3.0 1 1 1 2 2 2 0 SlyX Hydrolase_3 PF08282.12 EHT98664.1 - 1.9e-08 34.4 0.1 2e-08 34.3 0.1 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase MFS_1 PF07690.16 EHT98665.1 - 8.6e-45 153.2 33.5 7.7e-42 143.5 29.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_3 PF16083.5 EHT98665.1 - 0.01 16.0 9.3 1.6 8.9 1.9 4.2 4 1 0 4 4 4 0 LydA holin phage, holin superfamily III DUF2070 PF09843.9 EHT98665.1 - 4.5 5.4 9.8 0.3 9.3 3.6 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) EamA PF00892.20 EHT98666.1 - 9.8e-21 74.4 36.9 9.3e-12 45.3 9.6 2.0 2 0 0 2 2 2 2 EamA-like transporter family DUF1456 PF07308.13 EHT98667.1 - 2.8e-54 181.3 0.3 4.1e-27 94.3 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1456) LysR_substrate PF03466.20 EHT98668.1 - 3.7e-41 140.8 1.9 5.9e-41 140.1 1.9 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EHT98668.1 - 4e-17 61.9 2.2 7.5e-17 61.0 2.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 EHT98668.1 - 0.11 12.3 1.9 0.17 11.7 1.0 1.8 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_Tnp_1 PF01527.20 EHT98669.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT98669.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT98669.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT98669.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHT98670.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHT98671.1 - 1.2e-97 326.8 2.7 1.2e-96 323.5 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT98671.1 - 3.3e-16 59.2 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT98671.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT98671.1 - 8.9e-12 45.6 8.5 1.9e-11 44.6 8.5 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FUSC PF04632.12 EHT98671.1 - 0.046 12.3 7.1 0.072 11.6 7.1 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Phage_HK97_TLTM PF06120.11 EHT98671.1 - 0.046 12.9 1.3 0.09 12.0 1.3 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Exonuc_VII_L PF02601.15 EHT98671.1 - 0.05 13.2 1.7 0.072 12.6 0.5 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit LXG PF04740.12 EHT98671.1 - 0.1 12.3 1.6 0.81 9.4 0.3 2.2 1 1 1 2 2 2 0 LXG domain of WXG superfamily Csm1_N PF18504.1 EHT98671.1 - 0.13 12.6 3.2 0.93 9.9 0.2 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain FAM184 PF15665.5 EHT98671.1 - 0.15 11.8 4.7 0.24 11.2 4.7 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B DHR10 PF18595.1 EHT98671.1 - 0.18 11.9 10.2 0.31 11.1 10.2 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain HalX PF08663.10 EHT98671.1 - 0.22 11.8 2.3 0.6 10.5 2.3 1.7 1 0 0 1 1 1 0 HalX domain ALIX_LYPXL_bnd PF13949.6 EHT98671.1 - 0.23 10.7 4.0 0.39 9.9 4.0 1.3 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV TSNAXIP1_N PF15739.5 EHT98671.1 - 0.26 11.7 2.9 0.56 10.6 2.9 1.5 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus ERM PF00769.19 EHT98671.1 - 0.29 10.9 10.4 0.48 10.2 10.4 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HHH_8 PF14716.6 EHT98671.1 - 0.36 11.2 4.1 0.92 9.9 2.6 2.4 2 1 0 2 2 2 0 Helix-hairpin-helix domain Zn-ribbon_8 PF09723.10 EHT98671.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain CREPT PF16566.5 EHT98671.1 - 0.48 10.6 7.6 0.22 11.7 4.5 1.8 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour HAUS-augmin3 PF14932.6 EHT98671.1 - 1.2 8.6 6.9 2.9 7.4 6.9 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 ABC_tran_CTD PF16326.5 EHT98671.1 - 2 8.7 6.7 0.3 11.4 1.2 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain SlyX PF04102.12 EHT98671.1 - 7.6 7.2 8.3 15 6.3 1.9 3.0 1 1 1 2 2 2 0 SlyX DLH PF01738.18 EHT98672.1 - 3.1e-73 245.9 0.0 3.7e-73 245.6 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 EHT98672.1 - 2e-08 34.4 0.3 0.00023 21.1 0.3 2.7 1 1 2 3 3 3 2 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 EHT98672.1 - 5.4e-07 29.3 0.2 4.4e-05 23.0 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EHT98672.1 - 1.5e-05 24.8 0.1 0.0064 16.2 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EHT98672.1 - 2.6e-05 24.1 0.0 5.6e-05 23.0 0.0 1.5 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EHT98672.1 - 0.0011 19.6 1.9 0.07 13.7 1.9 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EHT98672.1 - 0.007 15.7 0.0 1.6 7.9 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 EHT98672.1 - 0.054 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein AP_endonuc_2 PF01261.24 EHT98672.1 - 0.068 12.6 0.1 0.47 9.8 0.0 2.1 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel Chlorophyllase PF07224.11 EHT98672.1 - 0.14 11.1 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase PNP_UDP_1 PF01048.20 EHT98673.1 - 6.4e-40 136.9 1.3 7.1e-40 136.7 1.3 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily RmuC PF02646.16 EHT98674.1 - 5.3e-104 347.4 0.8 5.3e-104 347.4 0.8 2.6 2 1 1 3 3 3 1 RmuC family Phage_GP20 PF06810.11 EHT98674.1 - 0.0011 18.8 9.2 0.26 11.1 0.1 2.4 2 0 0 2 2 2 2 Phage minor structural protein GP20 Tropomyosin_1 PF12718.7 EHT98674.1 - 0.005 17.0 22.3 0.005 17.0 22.3 3.2 2 1 1 3 3 3 1 Tropomyosin like Aminotran_1_2 PF00155.21 EHT98674.1 - 0.18 10.9 1.8 0.38 9.9 0.8 2.1 2 0 0 2 2 2 0 Aminotransferase class I and II G6B PF15096.6 EHT98674.1 - 0.18 11.5 0.1 0.4 10.4 0.1 1.5 1 0 0 1 1 1 0 G6B family DUF3573 PF12097.8 EHT98674.1 - 4.3 6.1 5.2 0.8 8.5 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) Ubie_methyltran PF01209.18 EHT98675.1 - 2.3e-103 344.6 0.0 2.6e-103 344.4 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EHT98675.1 - 3.9e-23 82.0 0.0 8.5e-23 80.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EHT98675.1 - 1e-21 77.3 0.0 2e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EHT98675.1 - 7.1e-19 68.1 0.0 1.1e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EHT98675.1 - 7.2e-16 58.5 0.0 9.8e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EHT98675.1 - 1e-11 45.5 0.0 1.8e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EHT98675.1 - 2.4e-08 34.0 0.0 3.9e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EHT98675.1 - 0.0002 21.0 0.0 0.00033 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.18 EHT98675.1 - 0.001 18.8 0.0 0.0021 17.8 0.0 1.6 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltr_RsmB-F PF01189.17 EHT98675.1 - 0.0022 17.6 0.0 0.011 15.4 0.0 2.0 2 1 0 2 2 2 1 16S rRNA methyltransferase RsmB/F RrnaAD PF00398.20 EHT98675.1 - 0.017 14.2 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MetW PF07021.12 EHT98675.1 - 0.018 14.7 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW GCD14 PF08704.10 EHT98675.1 - 0.025 14.3 0.0 0.12 12.0 0.0 1.9 1 1 1 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Sec_GG PF07549.14 EHT98675.1 - 0.11 12.0 0.2 2.5 7.7 0.0 2.6 2 0 0 2 2 2 0 SecD/SecF GG Motif SCP2 PF02036.17 EHT98676.1 - 3.3e-20 72.4 0.2 5e-20 71.9 0.2 1.2 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 EHT98676.1 - 0.0063 16.8 0.0 0.01 16.1 0.0 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal ABC1 PF03109.16 EHT98677.1 - 4.1e-35 120.5 0.0 7.9e-35 119.6 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EHT98677.1 - 0.11 12.4 0.0 1.2 9.0 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Protoglobin PF11563.8 EHT98677.1 - 0.14 12.0 0.1 0.33 10.8 0.1 1.6 1 0 0 1 1 1 0 Protoglobin MttA_Hcf106 PF02416.16 EHT98678.1 - 1.8e-16 59.2 0.0 3e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 mttA/Hcf106 family MttA_Hcf106 PF02416.16 EHT98679.1 - 0.00058 19.1 1.6 0.001 18.4 1.4 1.5 1 1 0 1 1 1 1 mttA/Hcf106 family DUF4455 PF14643.6 EHT98679.1 - 0.028 13.1 2.1 0.035 12.8 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) TEX13 PF15186.6 EHT98679.1 - 0.097 12.3 1.5 0.13 12.0 1.5 1.1 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family TatC PF00902.18 EHT98680.1 - 2.3e-66 223.6 23.0 2.8e-66 223.3 23.0 1.1 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) TMEM208_SND2 PF05620.11 EHT98680.1 - 2 8.2 0.0 2 8.2 0.0 3.4 2 1 1 4 4 4 0 SRP-independent targeting protein 2/TMEM208 DHHC PF01529.20 EHT98680.1 - 9.8 6.3 11.0 1.6e+02 2.3 7.5 3.0 2 1 1 3 3 3 0 DHHC palmitoyltransferase TatD_DNase PF01026.21 EHT98681.1 - 5.7e-68 229.1 0.0 6.5e-68 228.9 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 EHT98681.1 - 0.00054 19.8 1.6 0.0019 18.0 1.6 2.0 1 1 0 1 1 1 1 Amidohydrolase DRTGG PF07085.12 EHT98681.1 - 0.094 12.5 0.2 0.31 10.9 0.0 1.9 3 0 0 3 3 3 0 DRTGG domain NusG PF02357.19 EHT98682.1 - 2.6e-19 69.5 0.0 3.5e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Transcription termination factor nusG KOW PF00467.29 EHT98682.1 - 0.04 13.9 0.0 0.089 12.8 0.0 1.6 1 0 0 1 1 1 0 KOW motif UbiD PF01977.16 EHT98683.1 - 6e-171 568.8 0.0 7e-171 568.6 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase NAD_binding_1 PF00175.21 EHT98684.1 - 3.7e-22 79.0 0.0 5.8e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EHT98684.1 - 0.00044 20.5 0.0 0.00072 19.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EHT98684.1 - 0.15 12.2 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Thiolase_N PF00108.23 EHT98685.1 - 9.1e-83 277.6 0.4 1.3e-82 277.1 0.4 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EHT98685.1 - 9.5e-52 173.8 0.1 1.8e-51 173.0 0.1 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EHT98685.1 - 0.00014 21.5 0.3 0.0004 20.0 0.3 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EHT98685.1 - 0.064 13.1 0.1 2 8.3 0.0 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 3HCDH_N PF02737.18 EHT98686.1 - 6.6e-62 208.6 0.1 3.2e-61 206.3 0.1 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 EHT98686.1 - 6.3e-40 137.1 0.0 1e-39 136.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 EHT98686.1 - 6.4e-33 113.2 0.3 5e-24 84.7 0.1 3.1 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 EHT98686.1 - 7.2e-24 84.9 0.0 1.5e-23 83.9 0.0 1.5 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_M24 PF00557.24 EHT98687.1 - 2.8e-43 148.0 0.2 4e-43 147.6 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3793 PF12672.7 EHT98687.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) UPF0029 PF01205.19 EHT98688.1 - 6.7e-28 97.1 0.0 9.3e-28 96.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 DUF1949 PF09186.11 EHT98688.1 - 5.4e-13 48.6 0.0 8.5e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1949) EFG_C PF00679.24 EHT98688.1 - 0.042 13.9 0.0 0.081 13.0 0.0 1.3 1 0 0 1 1 1 0 Elongation factor G C-terminus TrkH PF02386.16 EHT98689.1 - 3.1e-90 303.0 14.1 6.2e-90 302.0 14.1 1.4 1 1 0 1 1 1 1 Cation transport protein TssN PF17555.2 EHT98689.1 - 4 6.7 11.8 0.074 12.4 0.6 2.7 2 1 1 3 3 3 0 Type VI secretion system, TssN Flavodoxin_5 PF12724.7 EHT98690.1 - 3.1e-51 173.4 0.0 3.7e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_3 PF12641.7 EHT98690.1 - 3.1e-07 30.2 0.0 3.7e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_1 PF00258.25 EHT98690.1 - 2.4e-05 24.5 0.1 4.5e-05 23.7 0.1 1.7 1 1 0 1 1 1 1 Flavodoxin Peptidase_S8 PF00082.22 EHT98690.1 - 0.15 11.3 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Subtilase family MobB PF03205.14 EHT98691.1 - 3.7e-49 166.0 0.0 4.5e-49 165.8 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 EHT98691.1 - 0.0017 18.0 0.0 0.003 17.2 0.0 1.5 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 EHT98691.1 - 0.0052 17.0 0.1 0.011 16.0 0.1 1.7 1 1 0 1 1 1 1 AAA domain LpxK PF02606.14 EHT98691.1 - 0.029 13.5 0.0 0.036 13.2 0.0 1.2 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase NTPase_1 PF03266.15 EHT98691.1 - 0.042 13.7 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_16 PF13191.6 EHT98691.1 - 0.055 13.8 0.0 0.064 13.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 EHT98691.1 - 0.078 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTP_transf_3 PF12804.7 EHT98692.1 - 2.1e-34 119.2 0.1 2.6e-34 118.9 0.1 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 EHT98692.1 - 0.0024 17.6 0.1 0.0038 17.0 0.1 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transferase PF00483.23 EHT98692.1 - 0.077 12.6 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Nucleotidyl transferase CTP_transf_3 PF02348.19 EHT98692.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase DUF1040 PF06288.13 EHT98693.1 - 6.4e-41 138.6 0.1 7.2e-41 138.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1040) APH PF01636.23 EHT98694.1 - 1.8e-41 142.6 3.4 1.8e-41 142.6 3.4 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 EHT98694.1 - 0.0095 15.3 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase DSBA PF01323.20 EHT98695.1 - 3.9e-26 92.0 3.5 7.4e-25 87.9 3.5 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 EHT98695.1 - 6.8e-11 42.6 0.0 9.4e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin PF00085.20 EHT98695.1 - 0.0015 18.5 0.1 0.3 11.1 0.1 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_5 PF13743.6 EHT98695.1 - 0.03 14.0 0.3 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin Glutaredoxin PF00462.24 EHT98695.1 - 0.097 12.9 0.2 0.91 9.8 0.0 2.2 2 0 0 2 2 2 0 Glutaredoxin Thioredoxin_3 PF13192.6 EHT98695.1 - 0.1 12.7 0.0 5.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin domain DUF3088 PF11287.8 EHT98695.1 - 0.16 11.7 0.0 2.7 7.8 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3088) DNA_pol_A PF00476.20 EHT98696.1 - 8e-155 515.5 0.0 1.1e-154 515.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A 5_3_exonuc_N PF02739.16 EHT98696.1 - 5.9e-55 185.5 0.0 1e-54 184.7 0.0 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain DNA_pol_A_exo1 PF01612.20 EHT98696.1 - 9.4e-41 139.4 1.1 1.7e-40 138.6 1.1 1.5 1 0 0 1 1 1 1 3'-5' exonuclease 5_3_exonuc PF01367.20 EHT98696.1 - 5.3e-29 100.7 0.0 1.7e-28 99.1 0.0 2.0 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH PF00633.23 EHT98696.1 - 0.01 15.7 0.1 0.038 13.9 0.1 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix motif SCP2 PF02036.17 EHT98696.1 - 0.05 14.1 0.2 0.27 11.7 0.0 2.3 2 0 0 2 2 2 0 SCP-2 sterol transfer family DUF2529 PF10740.9 EHT98696.1 - 0.076 12.6 0.0 0.23 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2529) HHH_5 PF14520.6 EHT98696.1 - 0.083 13.5 0.2 0.62 10.7 0.0 2.6 3 0 0 3 3 3 0 Helix-hairpin-helix domain MMR_HSR1 PF01926.23 EHT98697.1 - 1.2e-20 73.6 0.0 2e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EHT98697.1 - 1e-07 32.0 0.1 0.00054 19.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EHT98697.1 - 7.1e-06 25.6 0.0 9.7e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EHT98697.1 - 0.00023 21.3 0.0 0.15 12.1 0.1 2.2 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 EHT98697.1 - 0.0039 16.8 0.1 0.06 12.9 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EHT98697.1 - 0.012 15.0 0.0 0.024 14.0 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EHT98697.1 - 0.018 14.8 0.1 0.31 10.8 0.1 2.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PGM_PMM_I PF02878.16 EHT98697.1 - 0.019 14.7 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I FtsK_SpoIIIE PF01580.18 EHT98697.1 - 0.022 14.1 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.6 EHT98697.1 - 0.033 14.5 0.0 0.05 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain YihI PF04220.12 EHT98698.1 - 2.2e-56 189.9 9.6 2.5e-56 189.7 9.6 1.0 1 0 0 1 1 1 1 Der GTPase activator (YihI) DUF2228 PF10228.9 EHT98698.1 - 0.1 12.3 0.5 0.14 11.8 0.5 1.3 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) Radical_SAM PF04055.21 EHT98699.1 - 1.5e-17 64.4 0.1 2.4e-17 63.8 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily HemN_C PF06969.16 EHT98699.1 - 3.5e-09 36.6 0.0 1.1e-08 35.0 0.0 1.9 1 0 0 1 1 1 1 HemN C-terminal domain Acetyltransf_8 PF13523.6 EHT98699.1 - 0.034 13.8 0.0 0.069 12.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sigma54_activat PF00158.26 EHT98700.1 - 5.1e-70 234.5 0.0 8e-70 233.9 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 EHT98700.1 - 7.1e-31 106.7 0.0 1.3e-30 105.8 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activ_2 PF14532.6 EHT98700.1 - 4.9e-23 81.8 0.0 3.1e-22 79.2 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 EHT98700.1 - 5.9e-16 58.0 3.2 2e-15 56.3 1.5 2.4 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 EHT98700.1 - 1.7e-07 31.4 0.0 3.8e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EHT98700.1 - 2e-05 24.8 0.0 3.5e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 EHT98700.1 - 0.00081 19.8 0.0 0.0028 18.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EHT98700.1 - 0.0073 15.7 0.1 0.77 9.1 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI FleQ PF06490.11 EHT98700.1 - 0.014 15.7 0.0 0.041 14.3 0.0 1.8 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ AAA_7 PF12775.7 EHT98700.1 - 0.053 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 EHT98700.1 - 0.1 13.0 0.9 0.29 11.5 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain MCM PF00493.23 EHT98700.1 - 0.13 11.3 0.0 0.33 10.0 0.0 1.6 1 1 0 1 1 1 0 MCM P-loop domain HATPase_c PF02518.26 EHT98701.1 - 5.8e-17 62.2 0.0 1.3e-16 61.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EHT98701.1 - 6.4e-14 51.8 0.1 6.4e-14 51.8 0.1 2.6 3 1 1 4 4 4 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 EHT98701.1 - 5e-07 29.7 0.0 1.3e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EHT98701.1 - 4e-05 23.8 0.0 9.1e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 EHT98701.1 - 0.00013 21.9 0.0 0.00048 20.1 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS_9 PF13426.7 EHT98701.1 - 0.00048 20.4 0.0 0.001 19.3 0.0 1.5 1 0 0 1 1 1 1 PAS domain DUF1688 PF07958.11 EHT98701.1 - 0.016 14.0 0.2 0.023 13.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1688) HATPase_c_3 PF13589.6 EHT98701.1 - 0.045 13.6 0.0 0.073 12.9 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Gln-synt_C PF00120.24 EHT98702.1 - 3.5e-138 460.3 0.0 4.2e-138 460.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EHT98702.1 - 3.8e-32 109.9 0.2 7e-32 109.0 0.2 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain GTP_EFTU PF00009.27 EHT98703.1 - 2.2e-58 197.0 0.1 3.5e-58 196.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EHT98703.1 - 6.7e-21 74.1 0.0 1.9e-20 72.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EHT98703.1 - 1e-11 45.0 3.1 2.7e-11 43.7 3.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EHT98703.1 - 4.1e-07 30.1 0.6 2.3e-06 27.7 0.1 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase EFG_II PF14492.6 EHT98703.1 - 2.9e-05 24.1 1.5 9e-05 22.5 0.1 2.5 3 0 0 3 3 3 1 Elongation Factor G, domain II Septin PF00735.18 EHT98703.1 - 0.0011 18.3 0.1 0.0018 17.6 0.1 1.2 1 0 0 1 1 1 1 Septin FeoB_N PF02421.18 EHT98703.1 - 0.007 15.9 0.1 0.15 11.6 0.0 3.1 2 1 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EHT98703.1 - 0.019 15.0 0.1 0.31 11.1 0.0 2.5 2 1 0 2 2 2 0 Dynamin family Roc PF08477.13 EHT98703.1 - 0.04 14.1 0.0 0.071 13.3 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EHT98703.1 - 0.06 12.8 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NAGLU_N PF12971.7 EHT98703.1 - 0.18 11.6 0.0 0.42 10.4 0.0 1.6 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain HAD_2 PF13419.6 EHT98704.1 - 2.5e-10 40.7 0.0 3.4e-10 40.3 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EHT98704.1 - 2.8e-07 31.1 0.0 5.2e-06 26.9 0.0 2.0 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EHT98704.1 - 7.9e-06 25.9 0.1 2.4e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Acid_PPase PF12689.7 EHT98704.1 - 0.00036 20.4 0.0 0.00067 19.5 0.0 1.6 1 1 0 1 1 1 1 Acid Phosphatase PerC PF06069.11 EHT98704.1 - 0.004 17.4 0.0 0.0071 16.6 0.0 1.4 1 0 0 1 1 1 1 PerC transcriptional activator HAD PF12710.7 EHT98704.1 - 0.0078 16.6 0.1 0.016 15.6 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase SHOCT PF09851.9 EHT98704.1 - 0.17 11.7 0.9 0.24 11.2 0.2 1.6 2 0 0 2 2 2 0 Short C-terminal domain Virul_fac_BrkB PF03631.15 EHT98705.1 - 2.6e-56 191.1 27.0 3.1e-56 190.8 27.0 1.1 1 0 0 1 1 1 1 Virulence factor BrkB UCR_UQCRX_QCR9 PF05365.12 EHT98705.1 - 0.087 12.8 0.1 0.27 11.2 0.1 2.0 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Tyr_Deacylase PF02580.16 EHT98706.1 - 7.7e-53 178.9 0.0 9.5e-53 178.6 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase YiiD_C PF09500.10 EHT98707.1 - 4.8e-45 152.9 0.0 6.6e-45 152.5 0.0 1.2 1 0 0 1 1 1 1 Putative thioesterase (yiiD_Cterm) Acetyltransf_1 PF00583.25 EHT98707.1 - 3.5e-14 53.0 0.0 5.5e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EHT98707.1 - 3.1e-11 43.3 0.0 5.3e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EHT98707.1 - 6.8e-07 29.6 0.0 1.4e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EHT98707.1 - 0.00027 20.8 0.0 0.0006 19.7 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_5 PF13444.6 EHT98707.1 - 0.00072 20.2 0.0 0.0012 19.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4442 PF14539.6 EHT98707.1 - 0.088 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) Gram_pos_anchor PF00746.21 EHT98707.1 - 0.16 11.9 0.1 0.38 10.7 0.1 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif AsmA PF05170.14 EHT98708.1 - 3.5e-25 88.9 7.3 5.6e-25 88.2 7.3 1.3 1 1 0 1 1 1 1 AsmA family AsmA_2 PF13502.6 EHT98708.1 - 1e-06 28.5 14.4 0.00038 20.1 0.6 4.4 2 1 1 3 3 3 3 AsmA-like C-terminal region FixQ PF05545.11 EHT98708.1 - 1.5 8.8 5.2 2.7 8.0 5.2 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Xan_ur_permease PF00860.20 EHT98709.1 - 3.6e-106 355.1 41.1 4.8e-106 354.7 41.1 1.2 1 0 0 1 1 1 1 Permease family Wzy_C PF04932.15 EHT98709.1 - 0.033 13.8 0.5 0.033 13.8 0.5 4.0 3 1 0 3 3 3 0 O-Antigen ligase SprB PF13573.6 EHT98709.1 - 0.045 13.5 0.3 0.096 12.5 0.3 1.5 1 0 0 1 1 1 0 SprB repeat DUF3925 PF13063.6 EHT98709.1 - 0.27 11.5 3.8 0.35 11.1 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3925) DEAD PF00270.29 EHT98710.1 - 8.4e-20 71.3 1.0 1.9e-19 70.1 0.0 2.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase RecG_wedge PF17191.4 EHT98710.1 - 1.3e-18 67.2 0.0 2e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 RecG wedge domain Helicase_C PF00271.31 EHT98710.1 - 4.3e-18 65.7 0.0 7.6e-17 61.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EHT98710.1 - 2.7e-12 47.0 0.0 4.5e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit tRNA_anti-codon PF01336.25 EHT98710.1 - 8.2e-08 32.1 0.1 2.9e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain SecA_DEAD PF07517.14 EHT98710.1 - 6.5e-06 25.7 0.0 1.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 SecA DEAD-like domain AAA_30 PF13604.6 EHT98710.1 - 3.7e-05 23.5 1.7 3.7e-05 23.5 1.7 2.2 2 1 0 2 2 2 1 AAA domain SNF2_N PF00176.23 EHT98710.1 - 0.0017 17.1 0.0 0.0021 16.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF2075 PF09848.9 EHT98710.1 - 0.0084 15.4 0.1 0.012 14.9 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 EHT98710.1 - 0.024 14.5 0.2 0.061 13.2 0.1 1.7 2 0 0 2 2 2 0 Helicase DNA_pol_lambd_f PF10391.9 EHT98710.1 - 0.027 14.3 0.0 0.066 13.0 0.0 1.6 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda DUF2344 PF10105.9 EHT98710.1 - 0.036 13.9 0.0 0.32 10.8 0.0 2.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2344) PhoH PF02562.16 EHT98710.1 - 0.043 13.3 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein IMS_HHH PF11798.8 EHT98710.1 - 0.047 14.0 0.0 0.16 12.3 0.0 2.0 1 0 0 1 1 1 0 IMS family HHH motif AAA_22 PF13401.6 EHT98710.1 - 0.065 13.5 0.7 3.2 8.0 0.1 3.4 2 1 1 3 3 3 0 AAA domain PRTase_2 PF15609.6 EHT98710.1 - 0.082 12.4 0.0 0.43 10.1 0.0 2.1 2 0 0 2 2 2 0 Phosphoribosyl transferase ERCC3_RAD25_C PF16203.5 EHT98710.1 - 0.11 11.7 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Cdd1 PF11731.8 EHT98710.1 - 0.17 12.1 0.0 0.73 10.1 0.0 2.0 2 0 0 2 2 2 0 Pathogenicity locus SpoU_methylase PF00588.19 EHT98711.1 - 5.9e-37 127.0 0.2 8.1e-37 126.5 0.2 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_methylas_C PF12105.8 EHT98711.1 - 3.4e-23 81.1 1.1 5.2e-23 80.5 1.1 1.3 1 0 0 1 1 1 1 SpoU, rRNA methylase, C-terminal HD_4 PF13328.6 EHT98712.1 - 2.2e-52 176.9 0.7 4e-52 176.1 0.7 1.4 1 0 0 1 1 1 1 HD domain RelA_SpoT PF04607.17 EHT98712.1 - 2.8e-36 124.4 0.6 5.7e-36 123.3 0.1 1.8 2 0 0 2 2 2 1 Region found in RelA / SpoT proteins TGS PF02824.21 EHT98712.1 - 1.5e-21 76.1 0.0 3.8e-21 74.9 0.0 1.7 1 0 0 1 1 1 1 TGS domain ACT_4 PF13291.6 EHT98712.1 - 2.3e-16 60.1 1.8 1.7e-15 57.4 0.8 2.8 3 0 0 3 3 3 1 ACT domain HD PF01966.22 EHT98712.1 - 1.5e-12 47.8 2.6 1.9e-12 47.5 0.7 2.1 2 0 0 2 2 2 1 HD domain TFIIS_M PF07500.14 EHT98712.1 - 0.005 17.3 0.8 0.017 15.6 0.2 2.2 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain BEN PF10523.9 EHT98712.1 - 0.041 14.1 0.0 1 9.7 0.0 2.6 2 0 0 2 2 2 0 BEN domain EMC3_TMCO1 PF01956.16 EHT98712.1 - 0.15 11.8 0.4 0.31 10.8 0.4 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Terminase_2 PF03592.16 EHT98712.1 - 0.86 10.1 2.8 1.1e+02 3.2 0.1 3.9 4 0 0 4 4 4 0 Terminase small subunit RNA_pol_Rpb6 PF01192.22 EHT98713.1 - 4.9e-17 61.6 0.0 8e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 Guanylate_kin PF00625.21 EHT98714.1 - 6.1e-67 224.8 0.0 7e-67 224.6 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.6 EHT98714.1 - 9.1e-05 23.0 0.0 0.00017 22.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EHT98714.1 - 0.0004 20.6 0.0 0.0014 18.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EHT98714.1 - 0.00078 19.9 0.6 0.0043 17.5 0.6 1.9 1 1 0 1 1 1 1 AAA ATPase domain CPT PF07931.12 EHT98714.1 - 0.0015 18.4 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_22 PF13401.6 EHT98714.1 - 0.0022 18.2 0.3 0.026 14.8 0.3 2.3 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EHT98714.1 - 0.0028 17.6 0.1 0.0062 16.4 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 EHT98714.1 - 0.0054 17.3 0.0 0.0076 16.8 0.0 1.4 1 1 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 EHT98714.1 - 0.05 13.7 0.0 0.12 12.4 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.23 EHT98714.1 - 0.071 13.2 0.0 0.13 12.3 0.0 1.4 1 1 0 1 1 1 0 Dynamin family Viral_helicase1 PF01443.18 EHT98714.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 EHT98714.1 - 0.17 11.5 1.2 6.4 6.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain UPF0126 PF03458.13 EHT98715.1 - 2.1e-43 146.1 22.1 1.1e-21 76.5 7.4 2.3 2 0 0 2 2 2 2 UPF0126 domain TGBp3 PF02495.17 EHT98715.1 - 1.6 8.5 0.0 1.6 8.5 0.0 3.0 4 0 0 4 4 4 0 Triple gene block 3 ICMT PF04140.14 EHT98715.1 - 3.2 8.3 8.2 0.33 11.4 1.3 2.4 2 1 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PfkB PF00294.24 EHT98716.1 - 2.7e-62 210.8 0.0 3e-62 210.6 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EHT98716.1 - 0.0015 17.9 0.0 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Asparaginase_C PF17763.1 EHT98716.1 - 0.041 14.1 0.2 0.088 13.0 0.2 1.5 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain AP_endonuc_2 PF01261.24 EHT98717.1 - 1.4e-06 27.9 0.0 2.4e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Peripla_BP_3 PF13377.6 EHT98718.1 - 9.3e-21 74.9 0.1 1.3e-19 71.2 0.1 2.1 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 EHT98718.1 - 3.4e-18 66.0 0.0 4.5e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 EHT98718.1 - 1e-11 44.4 0.1 1.1e-10 41.1 0.0 2.3 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 EHT98718.1 - 5.6e-10 39.2 0.0 7.3e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain CbiJ PF02571.14 EHT98718.1 - 0.053 13.0 0.0 0.16 11.4 0.0 1.7 1 1 1 2 2 2 0 Precorrin-6x reductase CbiJ/CobK HTH_31 PF13560.6 EHT98718.1 - 0.15 12.4 0.0 0.15 12.4 0.0 3.1 3 1 0 3 3 3 0 Helix-turn-helix domain HTH_3 PF01381.22 EHT98718.1 - 0.16 12.1 0.0 0.43 10.7 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix Peripla_BP_1 PF00532.21 EHT98719.1 - 2.2e-32 112.6 0.2 3e-32 112.2 0.2 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 EHT98719.1 - 1.3e-12 48.4 0.7 2.3e-12 47.6 0.2 1.6 2 0 0 2 2 2 1 Periplasmic binding protein-like domain LacI PF00356.21 EHT98719.1 - 2e-09 37.1 0.2 3.4e-09 36.4 0.2 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 EHT98719.1 - 1.1e-05 25.1 0.3 1.6e-05 24.6 0.3 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain HTH_23 PF13384.6 EHT98719.1 - 0.0018 18.0 0.5 0.045 13.6 0.0 3.4 3 1 1 4 4 4 1 Homeodomain-like domain HTH_38 PF13936.6 EHT98719.1 - 0.0088 15.8 0.0 0.029 14.1 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 EHT98719.1 - 0.015 15.4 0.2 0.12 12.5 0.0 2.7 2 1 1 3 3 3 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 EHT98719.1 - 0.021 14.8 0.1 0.12 12.4 0.1 2.2 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Crp PF00325.20 EHT98719.1 - 0.025 14.2 0.1 0.059 13.0 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family HTH_Tnp_ISL3 PF13542.6 EHT98719.1 - 0.028 13.9 0.0 0.075 12.5 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4_2 PF08281.12 EHT98719.1 - 0.041 13.6 0.0 0.2 11.3 0.1 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_24 PF13412.6 EHT98719.1 - 0.062 12.9 0.1 0.16 11.5 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_3 PF01381.22 EHT98719.1 - 0.066 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix HTH_AsnC-type PF13404.6 EHT98719.1 - 0.085 12.7 0.7 0.55 10.1 0.1 2.7 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain OmpA PF00691.20 EHT98720.1 - 1.9e-21 76.3 0.1 2.7e-21 75.8 0.1 1.2 1 0 0 1 1 1 1 OmpA family Gly-zipper_Omp PF13488.6 EHT98720.1 - 7.7e-11 41.8 15.9 1.6e-10 40.8 15.9 1.5 1 0 0 1 1 1 1 Glycine zipper Gly-zipper_YMGG PF13441.6 EHT98720.1 - 2.9e-08 33.3 18.7 6e-08 32.3 18.7 1.5 1 0 0 1 1 1 1 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.15 EHT98720.1 - 0.00019 21.2 18.3 0.00045 20.0 18.3 1.6 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.6 EHT98720.1 - 0.065 13.0 25.4 0.46 10.3 25.5 2.2 1 1 0 1 1 1 0 Glycine-zipper domain Bacteriocin_IIc PF10439.9 EHT98720.1 - 0.29 11.3 12.2 0.64 10.2 12.2 1.6 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide TraT PF05818.12 EHT98720.1 - 6.2 6.4 8.8 8.4 6.0 8.8 1.3 1 1 0 1 1 1 0 Enterobacterial TraT complement resistance protein YtxH PF12732.7 EHT98720.1 - 8.1 7.1 15.1 0.73 10.4 1.6 2.7 2 1 0 2 2 2 0 YtxH-like protein Adenine_glyco PF03352.13 EHT98721.1 - 1.2e-77 259.7 0.1 1.3e-77 259.6 0.1 1.0 1 0 0 1 1 1 1 Methyladenine glycosylase DnaT PF17948.1 EHT98723.1 - 1.6e-24 85.4 1.3 2.7e-24 84.7 1.3 1.4 1 0 0 1 1 1 1 DnaT DNA-binding domain IstB_IS21 PF01695.17 EHT98724.1 - 3e-18 66.2 0.0 4.9e-18 65.5 0.0 1.3 1 1 0 1 1 1 1 IstB-like ATP binding protein Bac_DnaA PF00308.18 EHT98724.1 - 5e-05 23.3 0.0 6.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial dnaA protein AAA PF00004.29 EHT98724.1 - 6.9e-05 23.3 0.0 0.00011 22.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.14 EHT98724.1 - 0.00032 20.0 0.3 0.025 13.8 0.3 2.1 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EHT98724.1 - 0.00038 20.2 0.0 0.00073 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 EHT98724.1 - 0.0078 15.2 0.1 0.015 14.3 0.1 1.4 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Sigma54_activat PF00158.26 EHT98724.1 - 0.021 14.5 0.0 0.054 13.2 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.16 EHT98724.1 - 0.039 13.4 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein RuvB_N PF05496.12 EHT98724.1 - 0.047 13.4 0.2 0.19 11.4 0.2 1.8 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ArsA_ATPase PF02374.15 EHT98724.1 - 0.051 12.7 0.0 0.08 12.1 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase AAA_11 PF13086.6 EHT98724.1 - 0.18 11.6 0.1 3 7.6 0.0 2.1 1 1 1 2 2 2 0 AAA domain Torsin PF06309.11 EHT98724.1 - 0.2 11.8 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Torsin NTPase_1 PF03266.15 EHT98724.1 - 0.21 11.5 1.0 2.3 8.1 0.4 2.3 1 1 0 2 2 2 0 NTPase ROK PF00480.20 EHT98725.1 - 1.2e-38 133.3 0.0 1.6e-38 132.9 0.0 1.2 1 0 0 1 1 1 1 ROK family HTH_24 PF13412.6 EHT98725.1 - 0.00011 21.6 0.2 0.00032 20.2 0.2 1.8 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 EHT98725.1 - 0.00018 21.4 1.7 0.00047 20.0 0.2 2.5 3 0 0 3 3 3 1 MarR family MarR PF01047.22 EHT98725.1 - 0.00018 21.3 0.2 0.00049 20.0 0.2 1.7 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 EHT98725.1 - 0.00024 21.0 0.3 0.00062 19.7 0.3 1.7 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Phage_CI_repr PF07022.13 EHT98725.1 - 0.0012 18.9 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 Bacteriophage CI repressor helix-turn-helix domain HTH_36 PF13730.6 EHT98725.1 - 0.0024 17.8 0.1 0.0051 16.7 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_27 PF13463.6 EHT98725.1 - 0.0038 17.7 0.0 0.0086 16.6 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain Fe_dep_repress PF01325.19 EHT98725.1 - 0.0083 16.3 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_IclR PF09339.10 EHT98725.1 - 0.0085 15.9 0.1 0.033 14.0 0.1 2.1 2 0 0 2 2 1 1 IclR helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 EHT98725.1 - 0.03 13.7 0.1 0.07 12.6 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.12 EHT98725.1 - 0.052 13.5 0.2 0.13 12.2 0.2 1.7 1 0 0 1 1 1 0 HTH domain HTH_3 PF01381.22 EHT98725.1 - 0.063 13.3 0.3 0.15 12.1 0.3 1.7 1 0 0 1 1 1 0 Helix-turn-helix Crp PF00325.20 EHT98725.1 - 0.075 12.7 0.1 0.24 11.1 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family Sigma70_r4 PF04545.16 EHT98725.1 - 0.11 12.0 0.2 0.21 11.1 0.2 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 LacI PF00356.21 EHT98726.1 - 1.6e-18 66.2 0.7 3.7e-18 65.0 0.7 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_3 PF13377.6 EHT98726.1 - 9.3e-10 39.1 0.0 2.1e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Periplasmic binding protein-like domain HTH_31 PF13560.6 EHT98726.1 - 0.001 19.4 0.1 0.002 18.4 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 EHT98726.1 - 0.055 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix HTH_23 PF13384.6 EHT98726.1 - 0.066 13.0 0.2 3 7.8 0.0 2.7 1 1 1 2 2 2 0 Homeodomain-like domain HTH_38 PF13936.6 EHT98726.1 - 0.078 12.7 0.1 7.6 6.4 0.1 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_IclR PF09339.10 EHT98726.1 - 0.09 12.6 0.1 0.36 10.7 0.0 2.1 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 EHT98726.1 - 0.15 11.5 0.2 0.33 10.4 0.2 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 PTS_IIB PF02302.17 EHT98728.1 - 9.9e-19 67.8 0.0 1.1e-18 67.7 0.0 1.0 1 0 0 1 1 1 1 PTS system, Lactose/Cellobiose specific IIB subunit PTS_EIIC PF02378.18 EHT98729.1 - 7.4e-50 169.8 28.3 1.1e-49 169.2 28.3 1.3 1 0 0 1 1 1 1 Phosphotransferase system, EIIC Glyco_hydro_1 PF00232.18 EHT98730.1 - 4.1e-99 332.1 0.0 4.9e-99 331.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.18 EHT98730.1 - 0.17 11.3 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) 2-Hacid_dh_C PF02826.19 EHT98731.1 - 3.5e-64 215.4 0.0 5.1e-64 214.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EHT98731.1 - 2.1e-26 92.2 0.0 2.4e-26 92.0 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EHT98731.1 - 0.00029 21.1 0.2 0.0021 18.3 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EHT98731.1 - 0.072 13.7 0.0 0.22 12.1 0.0 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Aminotran_1_2 PF00155.21 EHT98732.1 - 2.4e-19 69.8 0.0 9.6e-19 67.8 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EHT98732.1 - 0.013 14.3 0.0 0.046 12.5 0.0 1.7 1 1 0 1 1 1 0 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.21 EHT98732.1 - 0.036 13.3 0.0 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase SepSecS PF05889.13 EHT98732.1 - 0.085 11.5 0.0 0.16 10.6 0.0 1.4 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS EamA PF00892.20 EHT98733.1 - 1.6e-33 115.8 46.2 1.4e-17 64.2 18.5 2.1 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 EHT98733.1 - 1.9e-06 27.1 15.9 3e-05 23.1 7.7 2.2 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like Transposase_31 PF04754.12 EHT98735.1 - 5.2e-84 280.9 0.0 6.9e-84 280.5 0.0 1.1 1 0 0 1 1 1 1 Putative transposase, YhgA-like Yae1_N PF09811.9 EHT98735.1 - 0.019 14.6 1.6 0.042 13.5 1.6 1.6 1 0 0 1 1 1 0 Essential protein Yae1, N terminal DUF2802 PF10975.8 EHT98735.1 - 0.094 12.9 0.1 0.24 11.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) HSP20 PF00011.21 EHT98736.1 - 1.5e-21 76.4 0.0 2e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EHT98736.1 - 0.00061 19.3 0.0 0.00088 18.8 0.0 1.2 1 0 0 1 1 1 1 HSP20-like domain found in ArsA DUF1375 PF07119.12 EHT98737.1 - 1.3e-09 38.3 1.4 2.5e-09 37.4 1.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1375) DUF3748 PF12566.8 EHT98738.1 - 3.3e-57 191.8 0.1 2e-54 182.7 0.1 4.2 4 1 1 5 5 5 1 Protein of unknown function (DUF3748) PD40 PF07676.12 EHT98738.1 - 2.2e-13 49.7 1.0 0.00083 19.2 0.0 5.8 5 0 0 5 5 5 4 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 EHT98738.1 - 1.4e-06 27.3 0.1 0.027 13.2 0.0 4.7 3 1 1 4 4 4 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region ANAPC4_WD40 PF12894.7 EHT98738.1 - 0.17 12.2 0.0 3.5 8.0 0.0 2.9 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Proteasome_A_N PF10584.9 EHT98738.1 - 0.25 11.1 4.5 7.9 6.3 0.0 3.4 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Hydrolase_3 PF08282.12 EHT98739.1 - 1.8e-68 231.1 0.0 2e-68 230.9 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EHT98739.1 - 2e-18 66.9 0.1 6e-10 39.1 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 EHT98739.1 - 8e-10 39.4 1.1 0.00033 21.0 0.2 3.5 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EHT98739.1 - 2e-05 25.1 0.7 0.25 11.7 0.0 3.5 1 1 3 4 4 4 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EHT98739.1 - 0.00013 22.1 0.0 0.045 13.8 0.0 2.6 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EHT98739.1 - 0.00019 21.5 0.0 0.0022 18.1 0.0 2.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EHT98739.1 - 0.035 14.2 0.1 0.45 10.6 0.0 2.3 2 0 0 2 2 2 0 HAD-hyrolase-like E3_binding PF02817.17 EHT98739.1 - 0.038 14.3 0.5 38 4.7 0.0 3.5 3 0 0 3 3 3 0 e3 binding domain DNA_gyraseB PF00204.25 EHT98740.1 - 1.8e-59 200.1 0.0 3.2e-59 199.3 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase B GyrB_insert PF18053.1 EHT98740.1 - 4e-48 163.5 0.0 7.5e-48 162.6 0.0 1.5 1 0 0 1 1 1 1 DNA gyrase B subunit insert domain DNA_gyraseB_C PF00986.21 EHT98740.1 - 9.7e-31 105.8 0.1 2.3e-30 104.6 0.1 1.7 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 EHT98740.1 - 1.6e-22 80.1 0.2 4.8e-22 78.6 0.2 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EHT98740.1 - 2.2e-18 66.4 0.0 1.1e-17 64.1 0.0 2.2 2 0 0 2 2 2 1 Toprim domain HATPase_c_3 PF13589.6 EHT98740.1 - 0.00047 20.0 0.1 0.0011 18.8 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SMC_N PF02463.19 EHT98741.1 - 4.1e-40 137.6 0.0 5e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EHT98741.1 - 1.8e-09 37.8 0.0 2.3e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EHT98741.1 - 2.5e-09 37.4 0.1 2.2e-06 27.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EHT98741.1 - 9.1e-08 32.8 0.1 1.7e-07 31.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_27 PF13514.6 EHT98741.1 - 2.7e-06 27.1 0.1 5.2e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EHT98741.1 - 0.00057 19.6 0.1 0.0032 17.2 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.27 EHT98741.1 - 0.0069 16.9 0.0 0.02 15.4 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 EHT98741.1 - 0.013 15.9 2.7 0.3 11.5 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain AAA_13 PF13166.6 EHT98741.1 - 0.095 11.3 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2813 PF11398.8 EHT98741.1 - 0.14 11.4 0.5 0.22 10.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) DNA_pol3_beta_2 PF02767.16 EHT98742.1 - 7.7e-46 155.1 0.0 2.3e-39 134.2 0.0 3.2 3 1 0 3 3 3 2 DNA polymerase III beta subunit, central domain DNA_pol3_beta_3 PF02768.15 EHT98742.1 - 8e-44 148.4 0.8 1.4e-43 147.6 0.2 1.7 2 0 0 2 2 2 1 DNA polymerase III beta subunit, C-terminal domain DNA_pol3_beta PF00712.19 EHT98742.1 - 8.3e-44 148.6 0.0 1.7e-39 134.6 0.0 3.1 3 0 0 3 3 3 3 DNA polymerase III beta subunit, N-terminal domain Bac_DnaA PF00308.18 EHT98743.1 - 1.1e-98 329.5 0.2 1.6e-98 328.9 0.2 1.3 1 0 0 1 1 1 1 Bacterial dnaA protein Bac_DnaA_C PF08299.11 EHT98743.1 - 2e-32 111.0 0.4 5.4e-32 109.6 0.1 1.9 2 0 0 2 2 2 1 Bacterial dnaA protein helix-turn-helix DnaA_N PF11638.8 EHT98743.1 - 4.9e-21 74.2 0.4 1.2e-20 73.0 0.4 1.7 1 0 0 1 1 1 1 DnaA N-terminal domain IstB_IS21 PF01695.17 EHT98743.1 - 8.4e-11 41.9 0.0 1.6e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA PF00004.29 EHT98743.1 - 2.9e-06 27.7 0.0 1.7e-05 25.3 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Kinesin PF00225.23 EHT98743.1 - 0.00042 19.4 0.0 0.0012 17.9 0.0 1.6 1 1 0 1 1 1 1 Kinesin motor domain AAA_14 PF13173.6 EHT98743.1 - 0.00097 19.2 0.1 0.015 15.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EHT98743.1 - 0.001 19.5 0.3 0.0064 16.9 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EHT98743.1 - 0.015 15.5 3.5 2.7 8.2 1.5 3.3 2 1 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.16 EHT98743.1 - 0.026 13.4 0.1 0.067 12.1 0.1 1.7 1 1 0 1 1 1 0 AFG1-like ATPase NACHT PF05729.12 EHT98743.1 - 0.033 14.1 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 EHT98743.1 - 0.045 13.7 0.1 0.14 12.0 0.1 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea DUF3037 PF11236.8 EHT98743.1 - 0.096 13.1 0.6 13 6.3 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3037) BLOC1S3 PF15753.5 EHT98743.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 AAA_19 PF13245.6 EHT98743.1 - 0.12 12.7 0.1 0.44 10.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain Ribosomal_L34 PF00468.17 EHT98744.1 - 1.8e-24 85.4 9.8 2e-24 85.3 9.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L34 Ribonuclease_P PF00825.18 EHT98745.1 - 7.2e-33 113.0 0.2 8.1e-33 112.8 0.2 1.0 1 0 0 1 1 1 1 Ribonuclease P YidD PF01809.18 EHT98746.1 - 2.1e-30 104.4 0.0 2.4e-30 104.2 0.0 1.0 1 0 0 1 1 1 1 Putative membrane protein insertion efficiency factor YidC_periplas PF14849.6 EHT98747.1 - 1.6e-91 307.1 3.5 2e-91 306.8 3.5 1.1 1 0 0 1 1 1 1 YidC periplasmic domain 60KD_IMP PF02096.20 EHT98747.1 - 1e-60 204.4 14.6 1.7e-60 203.7 14.6 1.4 1 0 0 1 1 1 1 60Kd inner membrane protein DUF2427 PF10348.9 EHT98747.1 - 1.1 9.1 6.2 0.12 12.2 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) MnmE_helical PF12631.7 EHT98748.1 - 4.3e-60 203.4 1.4 5.3e-60 203.1 1.4 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 EHT98748.1 - 2.3e-37 127.8 0.0 7.7e-37 126.1 0.0 1.9 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 EHT98748.1 - 1.2e-25 89.8 0.0 1.4e-24 86.4 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EHT98748.1 - 1.8e-08 34.0 0.0 7.5e-08 32.0 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EHT98748.1 - 4.8e-05 23.5 0.0 0.00068 19.7 0.0 2.2 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 EHT98748.1 - 0.00021 21.2 0.0 0.0068 16.3 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase Ras PF00071.22 EHT98748.1 - 0.00022 20.8 0.0 0.00039 20.0 0.0 1.4 1 0 0 1 1 1 1 Ras family AIG1 PF04548.16 EHT98748.1 - 0.00032 20.1 0.0 0.00051 19.4 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Roc PF08477.13 EHT98748.1 - 0.0011 19.1 0.0 0.0025 18.0 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 EHT98748.1 - 0.0013 19.3 0.0 0.0022 18.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_28 PF13521.6 EHT98748.1 - 0.011 16.0 0.0 0.026 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 EHT98748.1 - 0.014 14.9 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Arf PF00025.21 EHT98748.1 - 0.022 14.2 0.0 0.056 12.9 0.0 1.7 1 1 0 1 1 1 0 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EHT98748.1 - 0.057 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EHT98748.1 - 0.18 11.3 0.0 6.1 6.3 0.0 2.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Nitroreductase PF00881.24 EHT98749.1 - 3.6e-14 53.2 0.1 8.6e-14 51.9 0.1 1.5 1 1 0 1 1 1 1 Nitroreductase family Xan_ur_permease PF00860.20 EHT98750.1 - 3.7e-43 147.7 51.5 3.7e-43 147.7 51.5 1.5 1 1 1 2 2 2 1 Permease family HAD_2 PF13419.6 EHT98751.1 - 7.2e-22 78.3 0.0 8.5e-22 78.1 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EHT98751.1 - 1.6e-12 48.2 0.1 3.5e-11 43.8 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EHT98751.1 - 7e-05 23.3 0.0 0.00011 22.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EHT98751.1 - 0.0012 18.8 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EHT98751.1 - 0.045 13.9 0.0 0.39 10.8 0.0 2.2 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase NIF PF03031.18 EHT98751.1 - 0.14 11.9 0.0 1.1 9.0 0.0 2.1 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase Acyl_transf_3 PF01757.22 EHT98752.1 - 2.3e-27 96.0 37.2 2.9e-27 95.6 37.2 1.0 1 0 0 1 1 1 1 Acyltransferase family O-antigen_lig PF13425.6 EHT98752.1 - 0.01 14.7 5.5 0.02 13.7 5.5 1.5 1 1 0 1 1 1 0 O-antigen ligase like membrane protein DUF1600 PF07667.11 EHT98752.1 - 0.015 15.4 10.9 0.08 13.2 3.3 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1600) tRNA-synt_2e PF02091.15 EHT98753.1 - 6.4e-151 501.3 0.0 7.2e-151 501.1 0.0 1.0 1 0 0 1 1 1 1 Glycyl-tRNA synthetase alpha subunit tRNA_synt_2f PF02092.17 EHT98754.1 - 2.6e-213 709.8 0.0 3.7e-213 709.3 0.0 1.2 1 0 0 1 1 1 1 Glycyl-tRNA synthetase beta subunit DALR_1 PF05746.15 EHT98754.1 - 4.8e-08 33.2 1.3 1.2e-07 31.9 1.3 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain DDE_Tnp_IS66 PF03050.14 EHT98755.1 - 2.7e-98 328.9 5.1 5.3e-98 328.0 0.1 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT98755.1 - 2.9e-16 59.4 0.1 1.3e-15 57.3 0.1 2.3 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT98755.1 - 8.1e-15 55.0 1.3 1.9e-14 53.8 1.3 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT98755.1 - 1.6e-11 44.8 9.6 3.5e-11 43.7 9.6 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHT98755.1 - 0.016 15.0 6.4 0.027 14.3 6.4 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Phage_HK97_TLTM PF06120.11 EHT98755.1 - 0.021 14.0 1.7 0.042 13.0 1.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHT98755.1 - 0.021 15.1 4.3 0.091 13.1 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain FUSC PF04632.12 EHT98755.1 - 0.028 13.0 6.9 0.056 12.0 6.9 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 EHT98755.1 - 0.03 13.9 2.9 0.039 13.5 0.6 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit Tho2 PF11262.8 EHT98755.1 - 0.054 12.7 0.5 0.094 11.9 0.5 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Troponin PF00992.20 EHT98755.1 - 0.059 13.7 3.0 0.11 12.8 3.0 1.4 1 0 0 1 1 1 0 Troponin LXG PF04740.12 EHT98755.1 - 0.1 12.3 2.6 0.33 10.6 0.4 2.2 1 1 1 2 2 2 0 LXG domain of WXG superfamily UME PF08064.13 EHT98755.1 - 0.11 12.5 0.8 12 5.9 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain ERM PF00769.19 EHT98755.1 - 0.14 11.9 10.8 0.26 11.1 10.8 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HalX PF08663.10 EHT98755.1 - 0.22 11.9 3.1 0.59 10.5 3.1 1.7 1 0 0 1 1 1 0 HalX domain DHR10 PF18595.1 EHT98755.1 - 0.34 11.0 10.9 0.66 10.0 10.9 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF1192 PF06698.11 EHT98755.1 - 0.44 10.6 5.3 3.4 7.8 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHT98755.1 - 1.1 8.4 3.1 1.7 7.8 3.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHT98755.1 - 2.7 7.5 7.9 6.1 6.3 7.9 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHT98755.1 - 3 8.2 7.9 6.7 7.0 7.9 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 EHT98755.1 - 6.8 7.4 8.7 7.7 7.2 1.0 3.1 1 1 1 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHT98756.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHT98757.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT98757.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT98757.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT98757.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix GST_N_3 PF13417.6 EHT98758.1 - 2.6e-16 59.8 0.0 4.2e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EHT98758.1 - 2.4e-11 43.8 0.0 5.2e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EHT98758.1 - 4.2e-06 26.9 0.0 6.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EHT98758.1 - 9e-06 25.9 0.0 1.8e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EHT98758.1 - 0.00081 19.4 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FdhE PF04216.12 EHT98759.1 - 2.3e-108 362.4 2.4 2.7e-108 362.2 2.4 1.0 1 0 0 1 1 1 1 Protein involved in formate dehydrogenase formation Zn_Tnp_IS1595 PF12760.7 EHT98759.1 - 1.1 9.3 7.4 0.41 10.6 0.9 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Elf1 PF05129.13 EHT98759.1 - 1.1 9.4 4.2 8.7 6.5 2.7 2.2 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like DZR PF12773.7 EHT98759.1 - 3.6 7.7 9.1 20 5.3 5.9 2.5 2 1 0 2 2 2 0 Double zinc ribbon Ribosomal_L37e PF01907.19 EHT98759.1 - 4.1 7.7 6.3 0.89 9.8 1.7 2.0 2 0 0 2 2 2 0 Ribosomal protein L37e FdhD-NarQ PF02634.15 EHT98760.1 - 7.2e-71 238.6 0.0 8.6e-71 238.4 0.0 1.1 1 0 0 1 1 1 1 FdhD/NarQ family Sod_Fe_C PF02777.18 EHT98761.1 - 7.8e-42 141.6 0.7 1.7e-41 140.5 0.3 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EHT98761.1 - 4.4e-35 120.0 1.0 7.7e-35 119.2 1.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DUF535 PF04393.13 EHT98762.1 - 3.4e-93 312.0 0.3 3.9e-93 311.8 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF535) DUF2810 PF10928.8 EHT98763.1 - 4.7e-32 109.8 0.5 8e-32 109.0 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2810) FlgN PF05130.12 EHT98763.1 - 2.2e-05 25.0 8.5 2.8e-05 24.6 8.5 1.2 1 0 0 1 1 1 1 FlgN protein HALZ PF02183.18 EHT98763.1 - 0.071 13.3 1.1 0.071 13.3 1.1 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper Spc7 PF08317.11 EHT98763.1 - 0.58 9.0 9.3 0.36 9.7 4.5 1.9 1 1 0 2 2 2 0 Spc7 kinetochore protein FapA PF03961.13 EHT98763.1 - 0.91 8.1 4.8 0.96 8.0 4.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A HIP1_clath_bdg PF16515.5 EHT98763.1 - 0.95 10.1 10.7 0.23 12.1 5.4 2.0 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1192 PF06698.11 EHT98763.1 - 1 9.5 7.0 0.64 10.1 0.9 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) YlqD PF11068.8 EHT98763.1 - 4.9 7.5 9.3 6.4 7.2 9.3 1.2 1 0 0 1 1 1 0 YlqD protein Fungal_TACC PF12709.7 EHT98763.1 - 7.1 7.1 10.4 10 6.7 2.1 2.4 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins MtlR PF05068.12 EHT98764.1 - 1.2e-59 201.0 0.0 1.4e-59 200.8 0.0 1.1 1 0 0 1 1 1 1 Mannitol repressor Mannitol_dh_C PF08125.13 EHT98765.1 - 1.6e-69 234.1 0.0 2.5e-69 233.5 0.0 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 EHT98765.1 - 2.6e-26 92.6 0.1 5.3e-26 91.6 0.1 1.5 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain 3HCDH_N PF02737.18 EHT98765.1 - 0.024 14.5 0.2 0.13 12.2 0.1 2.1 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EHT98765.1 - 0.065 13.2 0.5 1.5 8.8 0.1 2.7 2 1 1 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sacchrp_dh_NADP PF03435.18 EHT98765.1 - 0.11 12.7 0.2 0.29 11.4 0.2 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain PTS_EIIA_2 PF00359.22 EHT98766.1 - 2.3e-32 111.9 0.0 4e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 PTS_EIIC PF02378.18 EHT98766.1 - 6.3e-18 64.9 35.6 6.3e-18 64.9 35.6 3.0 2 1 0 2 2 2 1 Phosphotransferase system, EIIC PTS_IIB PF02302.17 EHT98766.1 - 8.7e-10 39.2 0.0 2e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 PTS system, Lactose/Cellobiose specific IIB subunit DUF3053 PF11254.8 EHT98767.1 - 1.1e-88 296.5 8.3 1.3e-88 296.3 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3053) Dynactin_p22 PF07426.11 EHT98767.1 - 0.32 10.8 3.2 2.3 8.1 0.7 2.6 1 1 1 2 2 2 0 Dynactin subunit p22 HTH_3 PF01381.22 EHT98768.1 - 1.5e-06 28.1 0.0 2.4e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EHT98768.1 - 8.4e-06 26.0 0.0 1.3e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain MqsA_antitoxin PF15731.5 EHT98768.1 - 0.0008 19.5 0.0 0.0009 19.4 0.0 1.1 1 0 0 1 1 1 1 Antitoxin component of bacterial toxin-antitoxin system, MqsA Sigma70_r4_2 PF08281.12 EHT98768.1 - 0.00088 18.9 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 EHT98768.1 - 0.002 18.1 0.0 0.0021 17.9 0.0 1.2 1 0 0 1 1 1 1 ECF sigma factor HTH_19 PF12844.7 EHT98768.1 - 0.005 16.8 0.0 0.0092 16.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain DUF4447 PF14590.6 EHT98768.1 - 0.059 13.1 0.0 0.068 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4447) DUF1870 PF08965.10 EHT98768.1 - 0.092 12.8 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1870) HTH_23 PF13384.6 EHT98768.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT98768.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_terminase PF10668.9 EHT98768.1 - 0.12 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Phage terminase small subunit MerR_1 PF13411.6 EHT98768.1 - 0.16 12.1 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 MerR HTH family regulatory protein Trp_Tyr_perm PF03222.13 EHT98769.1 - 2.1e-138 461.7 32.4 2.4e-138 461.5 32.4 1.0 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family DUF5373 PF17343.2 EHT98769.1 - 0.51 10.1 3.8 1.7 8.5 3.8 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5373) Beta_elim_lyase PF01212.21 EHT98770.1 - 1.5e-89 300.2 0.0 1.7e-89 300.0 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EHT98770.1 - 8.6e-05 21.9 0.0 0.00047 19.4 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class I and II SepSecS PF05889.13 EHT98770.1 - 0.022 13.4 0.0 0.056 12.1 0.0 1.6 2 0 0 2 2 2 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS HD_4 PF13328.6 EHT98771.1 - 6.9e-22 77.9 1.5 8.8e-22 77.5 1.5 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.22 EHT98771.1 - 0.0015 18.7 0.2 0.0038 17.4 0.2 1.7 1 1 0 1 1 1 1 HD domain MarR PF01047.22 EHT98772.1 - 8.5e-18 64.0 0.1 1.5e-17 63.2 0.1 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 EHT98772.1 - 5.2e-12 46.1 0.1 1.5e-11 44.6 0.0 1.7 2 0 0 2 2 2 1 Winged helix DNA-binding domain MarR_2 PF12802.7 EHT98772.1 - 1.1e-11 44.4 0.0 1.7e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 MarR family TFIIE_alpha PF02002.17 EHT98772.1 - 4.5e-06 26.5 0.8 9.4e-05 22.2 0.1 2.4 2 1 1 3 3 3 1 TFIIE alpha subunit HTH_20 PF12840.7 EHT98772.1 - 1.1e-05 25.4 0.0 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.19 EHT98772.1 - 4.1e-05 23.4 0.0 0.00014 21.7 0.0 2.0 1 1 1 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 EHT98772.1 - 5.4e-05 22.7 0.0 8.5e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HxlR PF01638.17 EHT98772.1 - 7.6e-05 22.5 0.0 0.00013 21.7 0.0 1.3 1 0 0 1 1 1 1 HxlR-like helix-turn-helix Penicillinase_R PF03965.16 EHT98772.1 - 0.0002 21.7 0.0 0.00039 20.7 0.0 1.6 1 1 0 1 1 1 1 Penicillinase repressor HTH_34 PF13601.6 EHT98772.1 - 0.00021 21.4 0.0 0.00036 20.6 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_5 PF01022.20 EHT98772.1 - 0.00069 19.4 1.7 0.00091 19.0 0.0 2.1 3 0 0 3 3 1 1 Bacterial regulatory protein, arsR family PadR PF03551.14 EHT98772.1 - 0.0068 16.3 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family Rrf2 PF02082.20 EHT98772.1 - 0.0089 16.4 0.0 0.02 15.2 0.0 1.6 2 0 0 2 2 1 1 Transcriptional regulator HTH_IclR PF09339.10 EHT98772.1 - 0.022 14.5 0.1 0.038 13.8 0.1 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_DeoR PF08220.12 EHT98772.1 - 0.033 13.9 0.1 0.065 13.0 0.1 1.5 1 1 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_28 PF13518.6 EHT98772.1 - 0.037 14.2 0.0 0.064 13.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain B-block_TFIIIC PF04182.12 EHT98772.1 - 0.063 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC HTH_Crp_2 PF13545.6 EHT98772.1 - 0.071 13.1 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_23 PF13384.6 EHT98772.1 - 0.078 12.8 0.1 13 5.7 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain Mga PF05043.13 EHT98772.1 - 0.08 13.5 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 Mga helix-turn-helix domain DprA_WH PF17782.1 EHT98772.1 - 0.087 13.0 0.1 0.17 12.1 0.1 1.5 1 0 0 1 1 1 0 DprA winged helix domain Fe_dep_repress PF01325.19 EHT98772.1 - 0.092 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_micro PF17007.5 EHT98772.1 - 0.11 11.3 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 HTH-like GntR PF00392.21 EHT98772.1 - 0.18 11.5 0.7 0.44 10.2 0.1 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family OsmC PF02566.19 EHT98773.1 - 6.6e-17 61.8 0.0 9.5e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 OsmC-like protein Sulfatase PF00884.23 EHT98774.1 - 1.7e-43 149.2 0.1 2.3e-43 148.8 0.1 1.2 1 0 0 1 1 1 1 Sulfatase EptA_B_N PF08019.12 EHT98774.1 - 3.1e-20 72.6 7.9 3.1e-20 72.6 7.9 1.9 1 1 1 2 2 2 1 Phosphoethanolamine transferase EptA/EptB SBP_bac_5 PF00496.22 EHT98775.1 - 5.4e-111 371.2 8.5 6.6e-111 370.9 8.5 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle BPD_transp_1 PF00528.22 EHT98776.1 - 1.2e-46 158.7 12.8 1.2e-46 158.7 12.8 1.7 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component UPF0370 PF13980.6 EHT98776.1 - 0.36 10.9 2.0 0.62 10.1 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) BPD_transp_1 PF00528.22 EHT98777.1 - 5.8e-28 97.9 13.2 5.8e-28 97.9 13.2 2.4 3 0 0 3 3 3 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 EHT98777.1 - 5.5e-16 58.3 0.1 5.5e-16 58.3 0.1 4.1 4 0 0 4 4 4 2 N-terminal TM domain of oligopeptide transport permease C DUF624 PF04854.14 EHT98777.1 - 0.83 9.8 0.1 0.83 9.8 0.1 3.6 3 1 0 3 3 3 0 Protein of unknown function, DUF624 ABC_tran PF00005.27 EHT98778.1 - 8e-28 97.7 0.0 1.1e-27 97.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EHT98778.1 - 2.4e-18 66.4 0.1 4.4e-18 65.6 0.1 1.5 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region SMC_N PF02463.19 EHT98778.1 - 2.4e-08 33.7 0.0 3.5e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EHT98778.1 - 1e-06 28.8 0.1 1.4e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EHT98778.1 - 0.00081 19.7 1.8 0.43 10.8 0.1 2.2 2 0 0 2 2 2 2 AAA domain CNOT1_CAF1_bind PF16415.5 EHT98778.1 - 0.12 11.7 0.0 0.24 10.8 0.0 1.4 1 1 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 CAF1-binding domain Herpes_ori_bp PF02399.15 EHT98778.1 - 0.12 10.3 0.1 0.22 9.6 0.1 1.3 1 0 0 1 1 1 0 Origin of replication binding protein ABC_ATPase PF09818.9 EHT98778.1 - 0.14 10.9 0.2 0.38 9.5 0.2 1.7 1 1 0 1 1 1 0 Predicted ATPase of the ABC class AAA_29 PF13555.6 EHT98778.1 - 0.21 11.4 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EHT98779.1 - 4e-32 111.6 0.0 5.7e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EHT98779.1 - 2.6e-18 66.3 0.4 5.4e-18 65.3 0.4 1.6 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region SMC_N PF02463.19 EHT98779.1 - 0.0012 18.3 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EHT98779.1 - 0.0014 19.1 0.0 0.0025 18.2 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EHT98779.1 - 0.0014 18.9 1.1 0.0065 16.7 1.1 2.0 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EHT98779.1 - 0.0079 16.1 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EHT98779.1 - 0.026 14.3 0.1 0.049 13.4 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 EHT98779.1 - 0.028 14.3 0.0 6.2 6.5 0.0 2.2 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 EHT98779.1 - 0.06 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 EHT98779.1 - 0.079 13.4 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.6 EHT98779.1 - 0.13 12.8 0.0 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EHT98779.1 - 0.15 11.4 0.1 1 8.7 0.0 2.0 2 0 0 2 2 2 0 KaiC TniB PF05621.11 EHT98779.1 - 0.25 10.7 1.2 28 4.0 0.0 2.8 2 1 1 3 3 3 0 Bacterial TniB protein CBP_BcsO PF17037.5 EHT98780.1 - 7.3e-28 98.1 6.3 8.3e-28 97.9 6.3 1.0 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsO CBP_BcsQ PF06564.12 EHT98781.1 - 6.4e-40 137.1 0.0 8.8e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ CbiA PF01656.23 EHT98781.1 - 1.3e-19 70.5 0.0 2.8e-19 69.4 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EHT98781.1 - 4.6e-14 52.7 0.0 7.3e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain ParA PF10609.9 EHT98781.1 - 8.8e-12 45.0 0.3 1.5e-08 34.4 0.0 2.6 2 1 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase ArsA_ATPase PF02374.15 EHT98781.1 - 9e-06 25.1 0.0 1.3e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Anion-transporting ATPase Fer4_NifH PF00142.18 EHT98781.1 - 1e-05 25.1 0.0 0.0085 15.6 0.0 2.1 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_16 PF13191.6 EHT98781.1 - 2.1e-05 24.9 0.1 0.0052 17.2 0.0 2.2 1 1 1 2 2 2 2 AAA ATPase domain MipZ PF09140.11 EHT98781.1 - 4.6e-05 22.8 0.0 7.9e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 ATPase MipZ VirC1 PF07015.11 EHT98781.1 - 0.0065 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 VirC1 protein CLP1_P PF16575.5 EHT98781.1 - 0.0091 15.8 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_25 PF13481.6 EHT98781.1 - 0.016 14.8 0.1 0.13 11.8 0.1 2.0 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 EHT98781.1 - 0.09 12.4 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 EHT98781.1 - 0.2 11.4 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Glycos_transf_2 PF00535.26 EHT98782.1 - 1e-36 126.3 0.0 1.7e-36 125.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EHT98782.1 - 4e-24 85.8 0.0 5.9e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EHT98782.1 - 9.8e-21 74.6 0.3 9.8e-21 74.6 0.3 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 EHT98782.1 - 1.2e-16 60.7 0.0 1.9e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cellulose_synt PF03552.14 EHT98782.1 - 1e-13 50.8 6.6 7.6e-10 37.9 1.6 3.1 2 1 1 3 3 3 3 Cellulose synthase PilZ PF07238.14 EHT98782.1 - 0.00074 19.8 0.0 0.0015 18.9 0.0 1.5 1 0 0 1 1 1 1 PilZ domain BcsB PF03170.13 EHT98783.1 - 1.6e-197 657.6 3.4 2.2e-197 657.2 3.4 1.1 1 0 0 1 1 1 1 Bacterial cellulose synthase subunit BCSC_C PF05420.11 EHT98784.1 - 1.3e-135 451.9 11.5 2.8e-135 450.8 11.5 1.6 1 0 0 1 1 1 1 Cellulose synthase operon protein C C-terminus (BCSC_C) TPR_19 PF14559.6 EHT98784.1 - 1.8e-20 73.2 79.9 3.2e-07 30.7 1.1 12.3 6 5 8 14 14 14 7 Tetratricopeptide repeat TPR_14 PF13428.6 EHT98784.1 - 8.6e-12 44.8 70.3 0.0039 17.9 0.8 14.0 11 5 4 15 15 13 5 Tetratricopeptide repeat TPR_17 PF13431.6 EHT98784.1 - 2e-10 40.3 22.7 0.077 13.4 0.0 8.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 EHT98784.1 - 2e-08 34.7 73.6 1.1e-05 26.0 3.8 11.7 10 3 2 12 12 11 5 Tetratricopeptide repeat TPR_8 PF13181.6 EHT98784.1 - 1.3e-06 28.1 11.9 3.3 8.2 0.6 8.8 9 0 0 9 9 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EHT98784.1 - 2.1e-06 27.9 16.1 0.25 11.6 0.6 8.0 5 2 1 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EHT98784.1 - 0.00059 19.8 0.5 0.0017 18.3 1.6 11.1 13 0 0 13 13 12 2 Tetratricopeptide repeat TPR_20 PF14561.6 EHT98784.1 - 0.0035 17.6 58.3 0.09 13.1 0.2 10.6 8 3 3 11 11 11 3 Tetratricopeptide repeat Opacity PF02462.15 EHT98784.1 - 0.0088 16.2 2.6 0.045 13.8 0.2 2.7 2 0 0 2 2 2 1 Opacity family porin protein TPR_1 PF00515.28 EHT98784.1 - 0.0094 15.7 1.5 0.0094 15.7 1.5 7.6 10 0 0 10 10 8 1 Tetratricopeptide repeat OMP_b-brl PF13505.6 EHT98784.1 - 0.023 14.8 22.8 0.016 15.3 20.6 2.0 1 1 0 1 1 1 0 Outer membrane protein beta-barrel domain EF-G-binding_N PF07299.11 EHT98784.1 - 0.033 14.7 0.0 0.27 11.8 0.0 2.4 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal SPO22 PF08631.10 EHT98784.1 - 0.048 13.1 0.1 0.15 11.5 0.1 1.9 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like TPR_4 PF07721.14 EHT98784.1 - 0.075 13.7 0.2 0.074 13.7 0.8 10.9 12 0 0 12 12 10 0 Tetratricopeptide repeat NARP1 PF12569.8 EHT98784.1 - 0.11 11.4 3.2 0.53 9.1 0.1 3.2 2 1 2 4 4 4 0 NMDA receptor-regulated protein 1 TPR_11 PF13414.6 EHT98784.1 - 0.2 11.3 29.2 3.1 7.5 0.0 7.9 8 1 1 9 9 9 0 TPR repeat TPR_7 PF13176.6 EHT98784.1 - 0.29 11.3 18.1 0.24 11.5 0.9 5.9 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 EHT98784.1 - 0.85 9.8 36.9 0.042 14.0 1.3 7.5 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 EHT98784.1 - 0.86 9.9 33.2 0.27 11.6 8.0 6.9 6 1 2 8 8 7 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EHT98784.1 - 4.4 6.9 10.7 9.8 5.8 0.7 4.6 4 1 0 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) Fis1_TPR_C PF14853.6 EHT98784.1 - 5.7 7.1 11.6 2 8.6 0.1 4.7 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat Cellsynth_D PF03500.13 EHT98785.1 - 7.6e-11 42.1 0.0 9.3e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Cellulose synthase subunit D ATP-synt_C PF00137.21 EHT98785.1 - 0.063 13.6 0.1 0.13 12.6 0.1 1.5 1 0 0 1 1 1 0 ATP synthase subunit C Glyco_hydro_8 PF01270.17 EHT98786.1 - 2.8e-102 342.0 11.8 3.4e-102 341.8 11.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 8 EAL PF00563.20 EHT98787.1 - 8.9e-63 212.0 0.4 2.8e-62 210.4 0.4 1.9 1 0 0 1 1 1 1 EAL domain GAPES3 PF17154.4 EHT98787.1 - 3.5e-54 181.9 1.5 9.6e-54 180.5 1.5 1.8 1 0 0 1 1 1 1 Gammaproteobacterial periplasmic sensor domain GGDEF PF00990.21 EHT98787.1 - 3.6e-20 72.3 4.6 5.2e-20 71.8 1.4 2.7 2 1 1 3 3 3 1 Diguanylate cyclase, GGDEF domain HAMP PF00672.25 EHT98787.1 - 1.2e-07 32.0 0.0 4.6e-07 30.1 0.0 2.1 1 0 0 1 1 1 1 HAMP domain CHASE8 PF17152.4 EHT98787.1 - 0.012 15.8 0.1 0.76 10.1 0.0 3.2 3 0 0 3 3 3 0 Periplasmic sensor domain SDF PF00375.18 EHT98788.1 - 3.6e-112 375.2 42.3 4.1e-112 375.1 42.3 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Peptidase_M16_C PF05193.21 EHT98789.1 - 1.7e-16 60.8 0.0 3.1e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EHT98789.1 - 2.9e-06 27.3 0.0 6.8e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_S9 PF00326.21 EHT98790.1 - 1.1e-13 51.1 0.1 8.7e-11 41.7 0.0 2.6 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EHT98790.1 - 1e-11 45.1 0.3 2.4e-10 40.7 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 EHT98790.1 - 4e-05 23.3 0.0 0.004 16.7 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 EHT98790.1 - 0.00058 19.2 0.3 0.38 10.0 0.1 2.2 1 1 0 2 2 2 2 Serine aminopeptidase, S33 BAAT_C PF08840.11 EHT98790.1 - 0.0026 17.7 0.0 1.1 9.1 0.0 2.1 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 EHT98790.1 - 0.02 14.7 0.0 2.7 7.8 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EHT98790.1 - 0.024 15.2 4.7 0.13 12.8 4.7 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family FSH1 PF03959.13 EHT98790.1 - 0.2 11.3 0.0 0.49 10.0 0.0 1.6 1 1 0 1 1 1 0 Serine hydrolase (FSH1) PfkB PF00294.24 EHT98791.1 - 2.7e-66 223.9 0.0 3.1e-66 223.7 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase YpsA PF06908.11 EHT98791.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.6 2 0 0 2 2 2 0 YspA SLOG family Chlorophyllase2 PF12740.7 EHT98791.1 - 0.19 10.6 0.0 6.2 5.6 0.0 2.1 2 0 0 2 2 2 0 Chlorophyllase enzyme EAL PF00563.20 EHT98792.1 - 1.2e-27 96.9 0.0 1.6e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 EAL domain AsmA PF05170.14 EHT98793.1 - 9e-150 500.4 0.0 1e-149 500.2 0.0 1.0 1 0 0 1 1 1 1 AsmA family AsmA_2 PF13502.6 EHT98793.1 - 5.9e-15 55.4 11.6 6.6e-15 55.3 5.6 3.0 3 0 0 3 3 3 1 AsmA-like C-terminal region DUF748 PF05359.11 EHT98793.1 - 0.037 14.2 3.8 1.6 8.9 0.3 4.3 4 2 2 6 6 6 0 Domain of Unknown Function (DUF748) Rotamase PF00639.21 EHT98794.1 - 1.6e-19 70.7 0.0 2.2e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EHT98794.1 - 4.1e-19 69.2 0.0 4.7e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 EHT98794.1 - 1.2e-05 26.2 0.0 1.3e-05 26.0 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain UvrD-helicase PF00580.21 EHT98795.1 - 6.6e-75 252.5 1.7 7.5e-74 249.1 1.7 2.1 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 EHT98795.1 - 6e-72 242.9 0.7 5.9e-71 239.7 0.1 2.4 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EHT98795.1 - 4.4e-36 124.4 0.0 8.2e-36 123.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EHT98795.1 - 2.7e-10 39.9 0.0 1e-09 38.1 0.0 1.9 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 EHT98795.1 - 3.1e-09 36.8 0.6 0.00036 20.3 0.1 2.4 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 EHT98795.1 - 8e-07 29.0 0.4 0.022 14.5 0.0 3.8 3 1 1 4 4 4 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 EHT98795.1 - 0.035 13.7 0.0 3 7.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain Ppx-GppA PF02541.16 EHT98796.1 - 1.8e-93 313.1 1.1 2.6e-93 312.6 1.1 1.1 1 0 0 1 1 1 1 Ppx/GppA phosphatase family DDR PF08841.10 EHT98796.1 - 0.0086 15.1 0.1 0.016 14.2 0.1 1.5 1 0 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain DEAD PF00270.29 EHT98797.1 - 6.7e-47 159.5 0.0 3e-45 154.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EHT98797.1 - 2.2e-29 102.0 0.0 1e-28 99.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EHT98797.1 - 9.6e-06 25.7 0.0 1.6e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EHT98797.1 - 0.0015 17.8 0.0 0.0022 17.3 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 EHT98797.1 - 0.0062 16.8 0.2 0.022 15.1 0.2 1.9 1 1 0 1 1 1 1 AAA domain Thioredoxin PF00085.20 EHT98798.1 - 1.2e-33 115.2 0.0 1.3e-33 115.0 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EHT98798.1 - 1.2e-07 32.1 0.1 9.8e-07 29.2 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EHT98798.1 - 1.2e-06 28.7 0.0 9.6e-05 22.6 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like TraF PF13728.6 EHT98798.1 - 0.00031 20.6 0.0 0.0004 20.3 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 EHT98798.1 - 0.00051 19.8 0.0 0.00054 19.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.6 EHT98798.1 - 0.0017 18.4 0.0 0.0021 18.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain OST3_OST6 PF04756.13 EHT98798.1 - 0.0019 17.6 0.0 0.0021 17.5 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EHT98798.1 - 0.0037 17.2 0.0 0.0053 16.7 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EHT98798.1 - 0.0054 16.5 0.0 0.016 14.9 0.0 1.7 1 1 1 2 2 2 1 Redoxin Thioredoxin_6 PF13848.6 EHT98798.1 - 0.016 15.2 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EHT98798.1 - 0.044 14.0 0.0 0.073 13.3 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like DUF836 PF05768.14 EHT98798.1 - 0.062 13.7 0.0 0.091 13.2 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DSBA PF01323.20 EHT98798.1 - 0.098 12.4 0.0 2.8 7.7 0.0 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Rho_RNA_bind PF07497.12 EHT98799.1 - 2.8e-32 110.4 0.0 6.3e-32 109.3 0.0 1.6 1 0 0 1 1 1 1 Rho termination factor, RNA-binding domain ATP-synt_ab PF00006.25 EHT98799.1 - 9.6e-23 81.0 0.0 1.4e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Rho_N PF07498.12 EHT98799.1 - 2.6e-16 59.3 1.3 2e-15 56.4 0.2 2.7 3 0 0 3 3 3 1 Rho termination factor, N-terminal domain NACHT PF05729.12 EHT98799.1 - 1.3e-05 25.2 0.0 2.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain OB_RNB PF08206.11 EHT98799.1 - 0.002 17.8 0.0 0.0043 16.7 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease B OB domain AAA_25 PF13481.6 EHT98799.1 - 0.0028 17.3 0.0 0.01 15.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EHT98799.1 - 0.0041 17.5 0.0 0.0089 16.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EHT98799.1 - 0.0065 16.8 0.0 0.018 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Terminase_GpA PF05876.12 EHT98799.1 - 0.11 11.1 0.0 8.3 4.8 0.0 2.1 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) Glycos_transf_4 PF00953.21 EHT98800.1 - 8.7e-29 100.5 21.2 8.7e-29 100.5 21.2 2.6 2 1 1 3 3 3 1 Glycosyl transferase family 4 Wzz PF02706.15 EHT98801.1 - 2.6e-10 40.4 0.0 1.3e-09 38.2 0.0 2.2 3 0 0 3 3 3 1 Chain length determinant protein DUF4235 PF14019.6 EHT98801.1 - 0.00029 20.8 0.9 0.55 10.4 0.1 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF4235) Striatin PF08232.12 EHT98801.1 - 0.015 15.9 2.4 0.025 15.2 2.4 1.3 1 0 0 1 1 1 0 Striatin family DUF4893 PF16233.5 EHT98801.1 - 0.043 13.4 0.1 0.069 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4893) RGS PF00615.19 EHT98801.1 - 0.13 12.5 0.4 0.25 11.6 0.4 1.5 1 0 0 1 1 1 0 Regulator of G protein signaling domain GNVR PF13807.6 EHT98801.1 - 0.15 12.0 0.3 0.42 10.6 0.0 1.9 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase Epimerase_2 PF02350.19 EHT98802.1 - 1.1e-124 415.8 0.0 1.2e-124 415.7 0.0 1.0 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase UDPG_MGDP_dh_N PF03721.14 EHT98803.1 - 9.5e-60 201.4 0.0 3.5e-58 196.3 0.0 2.2 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 EHT98803.1 - 6e-26 90.5 0.0 1.1e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 EHT98803.1 - 5.4e-19 68.6 0.0 1.4e-18 67.2 0.0 1.8 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.15 EHT98803.1 - 1.6e-07 31.6 0.1 8.7e-07 29.2 0.0 2.2 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 EHT98803.1 - 4.5e-05 23.5 0.7 0.089 12.8 0.0 2.8 3 0 0 3 3 3 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 EHT98803.1 - 0.00014 21.8 0.5 0.00036 20.5 0.2 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EHT98803.1 - 0.00024 20.8 0.3 0.0079 15.8 0.0 3.0 3 0 0 3 3 3 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 EHT98803.1 - 0.00044 19.7 0.4 0.058 12.8 0.1 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 EHT98803.1 - 0.0089 16.3 0.7 0.019 15.3 0.1 1.9 2 0 0 2 2 2 1 TrkA-N domain TetR_C_11 PF16859.5 EHT98803.1 - 0.024 14.9 1.9 0.038 14.3 0.7 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Semialdhyde_dh PF01118.24 EHT98803.1 - 0.025 15.0 0.0 0.13 12.7 0.0 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 EHT98803.1 - 0.028 13.6 0.1 0.049 12.9 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EHT98803.1 - 0.036 14.6 0.1 0.11 13.1 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Mur_ligase PF01225.25 EHT98803.1 - 0.085 13.2 0.1 0.23 11.8 0.1 1.7 1 0 0 1 1 1 0 Mur ligase family, catalytic domain Methyltransf_25 PF13649.6 EHT98803.1 - 0.12 13.0 0.2 0.8 10.5 0.0 2.5 3 1 0 3 3 3 0 Methyltransferase domain F420_oxidored PF03807.17 EHT98803.1 - 0.2 12.3 2.8 4.7 7.9 0.1 2.9 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Acetyltransf_1 PF00583.25 EHT98804.1 - 2.1e-11 44.1 0.0 3.1e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EHT98804.1 - 1.8e-07 31.2 0.0 2.9e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EHT98804.1 - 3.4e-07 30.6 0.0 6e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EHT98804.1 - 8.4e-05 23.3 0.0 0.00022 21.9 0.0 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain HofP PF10748.9 EHT98804.1 - 0.0044 16.6 0.0 0.015 14.9 0.0 1.7 2 0 0 2 2 2 1 DNA utilization proteins HofP TonB_C PF03544.14 EHT98804.1 - 0.0077 16.6 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal DegT_DnrJ_EryC1 PF01041.17 EHT98805.1 - 9.5e-88 294.9 0.0 1.1e-87 294.6 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EHT98805.1 - 2.1e-09 37.0 0.2 7.5e-09 35.2 0.2 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EHT98805.1 - 2.1e-06 26.9 0.1 3.8e-06 26.1 0.1 1.6 1 1 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 EHT98805.1 - 0.001 17.9 0.0 0.003 16.3 0.0 1.8 2 1 0 2 2 2 1 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.21 EHT98805.1 - 0.004 16.5 0.0 0.0073 15.6 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EHT98805.1 - 0.055 12.0 0.1 0.083 11.4 0.1 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Polysacc_synt PF01943.17 EHT98806.1 - 2.9e-07 30.2 17.9 2.9e-07 30.2 17.9 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Glyco_transf_56 PF07429.11 EHT98807.1 - 1.7e-160 534.1 0.0 1.9e-160 533.9 0.0 1.0 1 0 0 1 1 1 1 4-alpha-L-fucosyltransferase glycosyl transferase group 56 WzyE PF06899.11 EHT98808.1 - 1.6e-242 805.2 38.5 1.8e-242 805.0 38.5 1.0 1 0 0 1 1 1 1 WzyE protein, O-antigen assembly polymerase Glyco_tran_WecB PF03808.13 EHT98809.1 - 1.5e-52 178.0 0.3 1.9e-52 177.6 0.3 1.1 1 0 0 1 1 1 1 Glycosyl transferase WecB/TagA/CpsF family MFS_1 PF07690.16 EHT98810.1 - 9.6e-50 169.5 57.5 3.7e-43 147.8 48.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EHT98810.1 - 1.9e-06 26.6 23.2 7.2e-05 21.4 10.5 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector MFS_4 PF06779.14 EHT98810.1 - 0.00012 21.5 9.8 0.00012 21.5 9.8 2.9 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 EHT98810.1 - 0.0015 17.0 21.6 0.0025 16.3 21.6 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Peripla_BP_3 PF13377.6 EHT98811.1 - 6.4e-44 150.2 0.0 1.2e-43 149.3 0.0 1.5 1 0 0 1 1 1 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 EHT98811.1 - 8.5e-33 114.0 0.0 1.1e-32 113.6 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 EHT98811.1 - 9.5e-21 73.3 0.2 1.7e-20 72.5 0.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 EHT98811.1 - 2e-19 70.2 0.0 2.8e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain HTH_Tnp_ISL3 PF13542.6 EHT98811.1 - 0.0047 16.3 0.2 0.0093 15.4 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_38 PF13936.6 EHT98811.1 - 0.0069 16.1 0.1 0.076 12.8 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_31 PF13560.6 EHT98811.1 - 0.012 16.0 0.0 0.025 14.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_3 PF01381.22 EHT98811.1 - 0.032 14.3 0.0 0.083 13.0 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix HTH_23 PF13384.6 EHT98811.1 - 0.043 13.6 0.0 0.098 12.5 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_17 PF12728.7 EHT98811.1 - 0.07 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain MerR PF00376.23 EHT98811.1 - 0.074 12.8 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 MerR family regulatory protein PfkB PF00294.24 EHT98812.1 - 1e-74 251.6 6.1 1.2e-74 251.4 6.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EHT98812.1 - 2e-13 50.3 0.5 2.8e-13 49.8 0.5 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.17 EHT98812.1 - 0.13 11.7 3.3 0.51 9.8 0.1 2.4 1 1 0 2 2 2 0 Carbohydrate kinase Thr_dehydrat_C PF00585.18 EHT98812.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 C-terminal regulatory domain of Threonine dehydratase Peripla_BP_4 PF13407.6 EHT98813.1 - 4.2e-59 200.2 7.7 4.9e-59 200.0 7.7 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 EHT98813.1 - 7.3e-28 97.8 1.0 8.8e-28 97.5 1.0 1.0 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 EHT98813.1 - 1.2e-14 55.0 0.0 5.3e-14 52.9 0.0 1.8 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_6 PF13458.6 EHT98813.1 - 6.6e-14 52.3 4.5 1.1e-13 51.6 4.1 1.4 1 1 1 2 2 2 1 Periplasmic binding protein ABC_sub_bind PF04392.12 EHT98813.1 - 0.00025 20.4 6.1 0.1 11.8 0.9 2.4 1 1 0 2 2 2 2 ABC transporter substrate binding protein PucR PF07905.11 EHT98813.1 - 0.0058 16.9 0.0 0.08 13.2 0.0 2.3 1 1 1 2 2 2 1 Purine catabolism regulatory protein-like family ANF_receptor PF01094.28 EHT98813.1 - 0.082 12.0 0.0 0.65 9.0 0.0 2.0 2 0 0 2 2 2 0 Receptor family ligand binding region IPT PF01745.16 EHT98813.1 - 0.11 11.9 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Isopentenyl transferase PCP_red PF08369.10 EHT98813.1 - 0.14 12.4 0.2 24 5.2 0.0 2.7 3 0 0 3 3 3 0 Proto-chlorophyllide reductase 57 kD subunit BPD_transp_2 PF02653.16 EHT98814.1 - 3.8e-53 180.4 41.5 3.8e-53 180.4 41.5 1.4 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component MccV PF17508.2 EHT98814.1 - 1.3 9.6 7.7 2.2 8.9 1.4 2.6 2 0 0 2 2 2 0 Microcin V bacteriocin ABC_tran PF00005.27 EHT98815.1 - 6.3e-54 182.2 0.0 2.2e-28 99.5 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EHT98815.1 - 4.6e-06 26.7 0.2 0.1 12.4 0.0 2.6 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EHT98815.1 - 5.8e-05 22.9 1.9 0.0058 16.4 0.3 2.8 3 0 0 3 3 3 1 AAA domain SMC_N PF02463.19 EHT98815.1 - 0.00066 19.2 0.0 0.022 14.2 0.0 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EHT98815.1 - 0.00096 19.1 0.3 0.031 14.2 0.1 2.6 3 0 0 3 3 2 1 RsgA GTPase Ploopntkinase3 PF18751.1 EHT98815.1 - 0.0049 16.8 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 P-loop Nucleotide Kinase3 AAA_29 PF13555.6 EHT98815.1 - 0.0089 15.8 0.7 0.02 14.6 0.1 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EHT98815.1 - 0.011 16.1 0.1 3.5 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain CTF_NFI PF00859.18 EHT98815.1 - 0.015 15.3 0.0 0.022 14.7 0.0 1.1 1 0 0 1 1 1 0 CTF/NF-I family transcription modulation region TsaE PF02367.17 EHT98815.1 - 0.015 15.3 1.4 2 8.4 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_ATPase PF09818.9 EHT98815.1 - 0.024 13.4 3.6 0.21 10.3 0.0 2.7 3 1 0 3 3 3 0 Predicted ATPase of the ABC class AAA_22 PF13401.6 EHT98815.1 - 0.037 14.3 2.2 0.76 10.0 0.1 3.3 4 0 0 4 4 4 0 AAA domain AAA_23 PF13476.6 EHT98815.1 - 0.048 14.2 0.1 0.096 13.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EHT98815.1 - 0.091 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain MukB PF04310.12 EHT98815.1 - 0.093 12.5 0.7 0.17 11.7 0.1 1.7 2 0 0 2 2 1 0 MukB N-terminal MMR_HSR1 PF01926.23 EHT98815.1 - 0.12 12.5 0.2 0.36 10.9 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase MeaB PF03308.16 EHT98815.1 - 0.24 10.4 2.8 21 4.0 0.1 3.2 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 EHT98815.1 - 0.25 11.2 1.3 56 3.6 0.1 3.6 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B RbsD_FucU PF05025.13 EHT98816.1 - 1.6e-49 167.8 0.1 1.8e-49 167.6 0.1 1.0 1 0 0 1 1 1 1 RbsD / FucU transport protein family DUF4527 PF15030.6 EHT98816.1 - 0.00021 20.8 0.0 0.00037 20.0 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF4527) PhnG PF06754.12 EHT98816.1 - 0.046 13.7 0.4 0.096 12.6 0.2 1.6 1 1 1 2 2 2 0 Phosphonate metabolism protein PhnG HydF_tetramer PF18133.1 EHT98816.1 - 0.051 13.3 0.1 0.073 12.8 0.1 1.3 1 0 0 1 1 1 0 Hydrogen maturase F tetramerization domain FAD-SLDH PF12318.8 EHT98816.1 - 0.091 12.8 0.3 0.13 12.3 0.3 1.4 1 1 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase BOF PF04076.13 EHT98817.1 - 1.1e-33 115.3 1.6 1.9e-33 114.6 1.6 1.4 1 1 0 1 1 1 1 Bacterial OB fold (BOF) protein tRNA_anti-codon PF01336.25 EHT98817.1 - 0.0068 16.4 0.2 0.34 10.9 0.1 2.1 1 1 1 2 2 2 2 OB-fold nucleic acid binding domain RcpC PF16976.5 EHT98817.1 - 0.022 14.8 0.1 5.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Flp pilus assembly protein RcpC/CpaB bPH_4 PF06713.11 EHT98817.1 - 0.051 13.6 0.0 0.084 13.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial PH domain Response_reg PF00072.24 EHT98818.1 - 9e-24 83.8 0.0 1.3e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 EHT98818.1 - 2e-23 82.3 0.2 4.7e-23 81.1 0.2 1.6 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal FleQ PF06490.11 EHT98818.1 - 0.0034 17.7 0.0 0.0054 17.1 0.0 1.4 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ OKR_DC_1_N PF03709.15 EHT98818.1 - 0.086 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain K_trans PF02705.16 EHT98819.1 - 1.7e-208 693.5 24.5 2e-208 693.3 24.5 1.0 1 0 0 1 1 1 1 K+ potassium transporter AAA_5 PF07728.14 EHT98820.1 - 1.2e-23 83.6 0.0 2.1e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_8 PF17868.1 EHT98820.1 - 5.9e-23 80.5 0.1 1.5e-22 79.2 0.1 1.8 1 0 0 1 1 1 1 AAA lid domain DUF3763 PF12592.8 EHT98820.1 - 3.7e-19 68.5 3.6 3.7e-19 68.5 3.6 2.5 2 0 0 2 2 1 1 Protein of unknown function (DUF3763) AAA_3 PF07726.11 EHT98820.1 - 6.4e-05 22.8 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EHT98820.1 - 0.00027 20.7 0.1 0.014 15.1 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 EHT98820.1 - 0.00036 20.0 0.0 0.0027 17.1 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA PF00004.29 EHT98820.1 - 0.0037 17.7 0.0 0.0099 16.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EHT98820.1 - 0.014 15.8 2.7 0.055 13.8 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 EHT98820.1 - 0.034 13.9 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 EHT98820.1 - 0.055 13.6 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.11 EHT98820.1 - 0.11 11.4 0.0 3.9 6.3 0.0 2.1 1 1 1 2 2 2 0 PrkA AAA domain DUF465 PF04325.13 EHT98820.1 - 0.31 11.1 4.9 0.17 12.0 1.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF465) VWA_CoxE PF05762.14 EHT98821.1 - 1.9e-08 34.0 0.0 3.3e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VWA_2 PF13519.6 EHT98821.1 - 6e-07 30.1 0.0 1.5e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF2201 PF09967.9 EHT98821.1 - 0.049 13.8 0.0 0.087 13.0 0.0 1.5 1 0 0 1 1 1 0 VWA-like domain (DUF2201) FGE-sulfatase PF03781.16 EHT98822.1 - 1.4e-26 93.6 4.8 2.2e-26 93.0 4.2 1.7 2 0 0 2 2 2 1 Sulfatase-modifying factor enzyme 1 Methyltransf_31 PF13847.6 EHT98822.1 - 4e-13 49.4 0.0 9.1e-06 25.5 0.0 2.9 1 1 2 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.6 EHT98822.1 - 1.2e-12 48.4 0.0 9.2e-07 29.5 0.0 2.8 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EHT98822.1 - 3.9e-12 46.7 0.0 8.5e-11 42.4 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EHT98822.1 - 3.7e-11 43.6 0.0 9.2e-10 39.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EHT98822.1 - 6.5e-11 42.3 0.0 1.4e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DinB_2 PF12867.7 EHT98822.1 - 1.4e-09 38.6 0.1 3.7e-09 37.2 0.1 1.8 1 0 0 1 1 1 1 DinB superfamily DREV PF05219.12 EHT98822.1 - 0.0024 17.0 0.0 0.024 13.7 0.0 2.1 2 0 0 2 2 2 1 DREV methyltransferase NodS PF05401.11 EHT98822.1 - 0.018 14.6 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Nodulation protein S (NodS) CheR PF01739.18 EHT98822.1 - 0.08 12.4 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain MTS PF05175.14 EHT98822.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain AsnC_trans_reg PF01037.21 EHT98823.1 - 5e-17 61.6 0.0 9.2e-17 60.8 0.0 1.5 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 EHT98823.1 - 3e-14 52.3 0.0 5.3e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 EHT98823.1 - 1e-13 50.9 0.0 1.9e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain MarR_2 PF12802.7 EHT98823.1 - 9.8e-05 22.2 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 EHT98823.1 - 0.00014 21.9 0.0 0.00024 21.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 EHT98823.1 - 0.00049 20.0 0.0 0.0012 18.8 0.0 1.7 1 0 0 1 1 1 1 HTH domain HTH_5 PF01022.20 EHT98823.1 - 0.0034 17.2 0.0 0.0071 16.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_Mga PF08280.11 EHT98823.1 - 0.018 15.0 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_28 PF13518.6 EHT98823.1 - 0.023 14.8 0.0 0.046 13.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain B-block_TFIIIC PF04182.12 EHT98823.1 - 0.057 13.6 0.1 0.35 11.0 0.0 2.1 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC HTH_41 PF14502.6 EHT98823.1 - 0.082 12.6 0.7 0.42 10.3 0.0 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain MarR PF01047.22 EHT98823.1 - 0.097 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_34 PF13601.6 EHT98823.1 - 0.098 12.9 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain Sigma70_r4_2 PF08281.12 EHT98823.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 TrmB PF01978.19 EHT98823.1 - 0.12 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Flavodoxin_1 PF00258.25 EHT98824.1 - 6.3e-26 91.3 0.0 7.2e-26 91.1 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin FMN_red PF03358.15 EHT98824.1 - 0.0017 18.1 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase GIDA PF01134.22 EHT98825.1 - 1.4e-169 564.3 0.0 1.9e-169 563.9 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 EHT98825.1 - 4.2e-77 259.1 0.5 6e-77 258.6 0.5 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 EHT98825.1 - 1.4e-07 31.3 4.3 2.9e-07 30.2 4.3 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EHT98825.1 - 1.7e-07 30.7 4.2 0.00018 20.8 0.2 2.9 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 EHT98825.1 - 1.9e-05 24.0 1.2 6.8e-05 22.2 1.2 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EHT98825.1 - 3.8e-05 23.1 0.8 0.0001 21.7 0.8 1.8 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 EHT98825.1 - 8.1e-05 21.5 2.3 0.0014 17.5 0.2 2.7 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.24 EHT98825.1 - 0.0022 17.6 0.5 1.9 8.0 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 EHT98825.1 - 0.016 15.8 0.2 0.063 13.8 0.2 2.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MarR_2 PF12802.7 EHT98825.1 - 0.033 14.1 0.0 0.096 12.6 0.0 1.8 1 0 0 1 1 1 0 MarR family Thi4 PF01946.17 EHT98825.1 - 0.039 13.2 1.7 0.31 10.2 1.7 2.0 1 1 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 EHT98825.1 - 0.14 11.4 0.0 0.33 10.2 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GidB PF02527.15 EHT98826.1 - 5.5e-63 211.6 0.0 6.7e-63 211.3 0.0 1.0 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.6 EHT98826.1 - 1.5e-05 24.8 0.0 2.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EHT98826.1 - 0.00011 22.8 0.0 0.0002 22.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EHT98826.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain ATP-synt_I PF03899.15 EHT98827.1 - 3.1e-14 53.2 16.6 4.1e-14 52.8 16.6 1.2 1 0 0 1 1 1 1 ATP synthase I chain SecE PF00584.20 EHT98827.1 - 3.3 7.7 12.6 7.4 6.6 1.4 2.5 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex ATP-synt_A PF00119.20 EHT98828.1 - 1.6e-54 185.1 20.4 1.9e-54 184.8 20.4 1.1 1 0 0 1 1 1 1 ATP synthase A chain DUF3333 PF11812.8 EHT98828.1 - 0.12 12.6 3.5 2.1 8.6 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3333) CHD5 PF04420.14 EHT98828.1 - 0.59 10.0 8.9 0.34 10.8 3.3 2.2 2 0 0 2 2 2 0 CHD5-like protein ATP-synt_C PF00137.21 EHT98829.1 - 2.4e-09 37.4 10.4 3.2e-09 37.0 10.1 1.3 1 1 0 1 1 1 1 ATP synthase subunit C HlyIII PF03006.20 EHT98829.1 - 0.037 13.8 0.4 0.043 13.5 0.4 1.2 1 0 0 1 1 1 0 Haemolysin-III related ATP-synt_B PF00430.18 EHT98830.1 - 2.2e-37 128.1 19.8 2.6e-37 127.8 19.8 1.1 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) Mt_ATP-synt_B PF05405.14 EHT98830.1 - 0.0002 21.0 4.6 0.00041 20.0 4.6 1.5 1 1 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) V-ATPase_G PF03179.15 EHT98830.1 - 0.011 16.2 21.3 0.03 14.8 17.8 2.6 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit DivIVA PF05103.13 EHT98830.1 - 0.045 13.8 21.9 0.033 14.3 17.9 2.1 1 1 1 2 2 2 0 DivIVA protein FNIP_C PF14638.6 EHT98830.1 - 0.091 12.4 0.1 0.15 11.7 0.0 1.4 2 0 0 2 2 2 0 Folliculin-interacting protein C-terminus ESM4 PF15952.5 EHT98830.1 - 0.22 12.0 4.7 0.46 10.9 4.7 1.5 1 1 0 1 1 1 0 Enhancer of split M4 family RNA_pol_Rpb2_45 PF10385.9 EHT98830.1 - 0.26 11.6 10.7 0.098 12.9 1.1 3.1 2 1 1 3 3 3 0 RNA polymerase beta subunit external 1 domain V-ATPase_G_2 PF16999.5 EHT98830.1 - 0.35 11.3 25.3 0.4 11.1 24.3 1.7 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit CRISPR_Cse1 PF09481.10 EHT98830.1 - 1.7 7.6 7.4 2.2 7.3 7.4 1.0 1 0 0 1 1 1 0 CRISPR-associated protein Cse1 (CRISPR_cse1) OSCP PF00213.18 EHT98831.1 - 2.2e-49 167.9 0.7 2.5e-49 167.7 0.7 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit ATP-synt_ab PF00006.25 EHT98832.1 - 2.1e-72 243.2 0.1 3.5e-72 242.5 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 EHT98832.1 - 1.7e-44 151.1 2.1 2.8e-44 150.5 1.8 1.5 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 EHT98832.1 - 7.8e-14 52.0 0.2 1.8e-13 50.8 0.2 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 EHT98832.1 - 8.5e-05 22.0 0.1 0.00015 21.2 0.1 1.4 1 0 0 1 1 1 1 KaiC HAS-barrel PF09378.10 EHT98832.1 - 0.00045 20.3 0.3 0.0017 18.5 0.1 2.1 2 1 0 2 2 2 1 HAS barrel domain ATPase_2 PF01637.18 EHT98832.1 - 0.074 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Viral_cys_rich PF08008.12 EHT98832.1 - 0.13 12.3 0.0 6.9 6.8 0.0 2.9 2 1 1 3 3 3 0 Viral cysteine rich ATP-synt PF00231.19 EHT98833.1 - 2.9e-96 322.5 0.0 3.2e-96 322.3 0.0 1.0 1 0 0 1 1 1 1 ATP synthase ATP-synt_ab PF00006.25 EHT98834.1 - 1.3e-63 214.5 0.0 1.7e-63 214.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EHT98834.1 - 1.1e-19 70.7 2.2 2.4e-19 69.6 2.2 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain T3SS_ATPase_C PF18269.1 EHT98834.1 - 0.014 15.3 0.5 0.083 12.8 0.5 2.2 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain TrwB_AAD_bind PF10412.9 EHT98834.1 - 0.14 11.1 0.1 0.26 10.1 0.1 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Erythro-docking PF09277.11 EHT98834.1 - 0.15 12.0 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 Erythronolide synthase, docking RNA_helicase PF00910.22 EHT98834.1 - 0.2 12.1 0.0 0.35 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase ATP-synt_DE_N PF02823.16 EHT98835.1 - 3.7e-28 97.3 0.0 5.2e-28 96.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ATP-synt_DE PF00401.20 EHT98835.1 - 4.8e-14 52.3 4.6 7.6e-14 51.7 4.6 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Hexapep PF00132.24 EHT98836.1 - 8.7e-23 79.1 12.5 2.7e-06 26.8 3.5 5.1 2 1 3 5 5 5 5 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EHT98836.1 - 1.2e-22 81.0 0.3 2.3e-22 80.1 0.3 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 EHT98836.1 - 1.5e-12 47.6 0.0 2.4e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase IspD PF01128.19 EHT98836.1 - 2.9e-07 30.5 0.1 5.7e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Hexapep_2 PF14602.6 EHT98836.1 - 5.1e-06 26.1 17.4 0.0025 17.5 0.1 4.3 4 1 1 5 5 5 3 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.19 EHT98836.1 - 0.00041 20.4 0.0 0.071 13.0 0.0 2.4 2 0 0 2 2 2 1 Cytidylyltransferase Fucokinase PF07959.12 EHT98836.1 - 0.0012 17.9 0.1 0.034 13.1 0.2 2.5 1 1 1 3 3 3 1 L-fucokinase CofC PF01983.16 EHT98836.1 - 0.0091 15.2 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Guanylyl transferase CofC like Bactofilin PF04519.13 EHT98836.1 - 0.11 12.8 2.5 0.25 11.6 0.1 2.5 2 1 0 2 2 2 0 Polymer-forming cytoskeletal SIS PF01380.22 EHT98837.1 - 3.6e-63 211.2 0.3 6.1e-33 113.5 0.3 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 EHT98837.1 - 2.7e-22 79.4 0.1 5.1e-22 78.5 0.1 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EHT98837.1 - 1.2e-16 60.7 0.0 2.5e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EHT98837.1 - 0.00022 20.2 0.1 0.00064 18.7 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferases class-II DUF3677 PF12432.8 EHT98837.1 - 0.076 13.3 0.0 13 6.2 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3677) PBP_like_2 PF12849.7 EHT98839.1 - 2.5e-57 194.7 9.5 3.3e-57 194.3 9.5 1.1 1 0 0 1 1 1 1 PBP superfamily domain PBP_like PF12727.7 EHT98839.1 - 3.1e-12 46.0 0.0 7e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 PBP superfamily domain BPD_transp_1 PF00528.22 EHT98840.1 - 5.4e-18 65.4 19.9 5.4e-18 65.4 19.9 2.2 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 EHT98841.1 - 1.2e-29 103.4 17.1 1.2e-29 103.4 17.1 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 EHT98842.1 - 1.2e-34 119.7 0.0 1.8e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EHT98842.1 - 4.9e-10 39.7 0.1 0.00016 21.6 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EHT98842.1 - 3.4e-07 29.9 0.0 4.1e-06 26.4 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EHT98842.1 - 1.8e-05 24.7 0.0 1.8e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EHT98842.1 - 6.9e-05 22.5 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EHT98842.1 - 7.7e-05 23.0 0.0 0.00026 21.3 0.0 1.9 1 1 1 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EHT98842.1 - 0.0001 22.2 0.0 0.00024 21.1 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 EHT98842.1 - 0.00011 22.8 0.2 0.00014 22.4 0.2 1.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EHT98842.1 - 0.00018 22.0 0.0 0.00037 20.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 EHT98842.1 - 0.0004 20.4 0.0 0.00064 19.7 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 EHT98842.1 - 0.011 15.5 0.0 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EHT98842.1 - 0.021 15.0 0.0 0.078 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EHT98842.1 - 0.047 13.1 0.0 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein PRK PF00485.18 EHT98842.1 - 0.048 13.4 0.0 0.17 11.6 0.0 1.9 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family G-alpha PF00503.20 EHT98842.1 - 0.05 12.8 0.0 0.05 12.8 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit ATPase_2 PF01637.18 EHT98842.1 - 0.078 12.9 0.0 0.55 10.1 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea PhoH PF02562.16 EHT98842.1 - 0.082 12.4 0.0 0.28 10.6 0.0 1.9 1 1 0 1 1 1 0 PhoH-like protein Adeno_IVa2 PF02456.15 EHT98842.1 - 0.096 11.5 0.0 0.32 9.8 0.0 1.7 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_25 PF13481.6 EHT98842.1 - 0.1 12.1 0.1 0.4 10.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EHT98842.1 - 0.11 12.2 0.3 2.2 8.0 0.0 2.6 2 1 0 3 3 3 0 IstB-like ATP binding protein AAA_24 PF13479.6 EHT98842.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EHT98842.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EHT98842.1 - 0.15 12.0 0.0 0.38 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PhoU PF01895.19 EHT98843.1 - 3.6e-39 133.1 9.0 8.2e-21 74.3 2.8 2.1 2 0 0 2 2 2 2 PhoU domain Mst1_SARAH PF11629.8 EHT98843.1 - 0.12 12.5 0.1 0.58 10.3 0.0 2.3 2 1 0 2 2 2 0 C terminal SARAH domain of Mst1 Acetyltransf_1 PF00583.25 EHT98844.1 - 0.001 19.3 0.0 0.0015 18.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 EHT98844.1 - 0.0013 19.4 0.0 0.0018 19.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EHT98844.1 - 0.015 15.7 0.0 0.02 15.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 EHT98844.1 - 0.046 13.7 0.0 0.074 13.0 0.0 1.5 1 1 0 1 1 1 0 FR47-like protein FGGY_N PF00370.21 EHT98845.1 - 1.2e-82 277.2 0.0 1.6e-82 276.8 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EHT98845.1 - 1.6e-32 112.9 0.1 2.7e-32 112.1 0.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 EHT98845.1 - 0.0039 16.7 0.0 0.088 12.3 0.0 2.2 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family AP_endonuc_2 PF01261.24 EHT98846.1 - 0.00042 19.8 0.0 0.00098 18.6 0.0 1.6 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel DDE_3 PF13358.6 EHT98847.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHT98847.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHT98847.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHT98847.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHT98847.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHT98847.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHT98847.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHT98847.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 ABC_tran PF00005.27 EHT98848.1 - 6.9e-54 182.1 0.3 2.3e-31 109.2 0.1 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EHT98848.1 - 2.4e-12 47.3 0.9 0.0001 22.3 0.0 3.1 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EHT98848.1 - 6.8e-05 22.4 0.7 0.88 9.0 0.0 3.2 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EHT98848.1 - 0.00077 19.2 0.0 0.0024 17.6 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EHT98848.1 - 0.0017 18.1 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EHT98848.1 - 0.0043 17.6 0.0 0.0094 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Ad_Cy_reg PF16701.5 EHT98848.1 - 0.02 14.7 0.3 0.3 10.8 0.0 2.3 2 0 0 2 2 2 0 Adenylate cyclase regulatory domain SbcCD_C PF13558.6 EHT98848.1 - 0.024 14.9 0.0 2.6 8.3 0.0 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.9 EHT98848.1 - 0.025 13.4 1.2 3.3 6.4 0.1 3.3 3 1 0 3 3 3 0 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 EHT98848.1 - 0.028 14.3 0.0 0.18 11.7 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase Rad17 PF03215.15 EHT98848.1 - 0.051 13.5 0.0 0.44 10.5 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_22 PF13401.6 EHT98848.1 - 0.062 13.6 10.5 0.023 14.9 2.3 3.6 4 1 0 4 4 4 0 AAA domain TsaE PF02367.17 EHT98848.1 - 0.071 13.1 0.1 1.9 8.5 0.0 2.6 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EHT98848.1 - 0.091 12.7 0.1 0.43 10.5 0.0 2.1 2 0 0 2 2 2 0 NACHT domain DEAD PF00270.29 EHT98848.1 - 0.12 12.1 0.9 5.7 6.7 0.5 2.8 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_33 PF13671.6 EHT98848.1 - 0.13 12.4 0.1 1.7 8.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain BPD_transp_2 PF02653.16 EHT98849.1 - 2.2e-45 154.9 49.4 2.2e-45 154.9 49.4 2.2 2 1 0 2 2 2 1 Branched-chain amino acid transport system / permease component DUF1072 PF06380.11 EHT98849.1 - 0.56 10.1 3.6 2.4 8.1 3.6 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1072) Peripla_BP_3 PF13377.6 EHT98850.1 - 2e-34 119.3 0.1 3.8e-34 118.4 0.1 1.5 2 0 0 2 2 2 1 Periplasmic binding protein-like domain HTH_18 PF12833.7 EHT98850.1 - 4.8e-19 68.4 0.0 1.5e-18 66.8 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 EHT98850.1 - 3.1e-17 62.2 0.1 1.1e-09 38.1 0.2 2.6 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Peripla_BP_4 PF13407.6 EHT98850.1 - 5.8e-10 39.2 0.0 8.4e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_6 PF13458.6 EHT98850.1 - 0.031 14.0 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein DUF4539 PF15072.6 EHT98850.1 - 0.096 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) Acetyltransf_1 PF00583.25 EHT98851.1 - 4.7e-15 55.8 0.0 5.9e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EHT98851.1 - 1.4e-07 31.5 0.0 1.8e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EHT98851.1 - 3.9e-07 30.4 0.0 4.9e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EHT98851.1 - 1.1e-06 28.4 0.0 1.7e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EHT98851.1 - 0.0026 17.8 0.0 0.0038 17.3 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase WI12 PF07107.11 EHT98851.1 - 0.02 15.0 0.5 2.4 8.3 0.0 2.1 1 1 1 2 2 2 0 Wound-induced protein WI12 Acetyltransf_6 PF13480.7 EHT98851.1 - 0.13 12.4 0.0 0.19 11.9 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain OsmC PF02566.19 EHT98853.1 - 4.9e-06 26.9 0.0 5.3e-06 26.8 0.0 1.0 1 0 0 1 1 1 1 OsmC-like protein YjfB_motility PF14070.6 EHT98854.1 - 3.2e-09 36.8 0.1 4e-09 36.5 0.1 1.2 1 0 0 1 1 1 1 Putative motility protein LysE PF01810.18 EHT98855.1 - 5.1e-19 68.5 8.0 6.4e-19 68.2 8.0 1.1 1 0 0 1 1 1 1 LysE type translocator zf-CHC2 PF01807.20 EHT98856.1 - 0.058 13.2 0.0 0.078 12.8 0.0 1.3 1 0 0 1 1 1 0 CHC2 zinc finger AntA PF08346.12 EHT98857.1 - 8.3e-22 77.5 0.0 1.1e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 AntA/AntB antirepressor DDE_3 PF13358.6 EHT98858.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHT98858.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHT98858.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHT98858.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHT98858.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHT98858.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHT98858.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHT98858.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 Phage_AlpA PF05930.12 EHT98859.1 - 1.9e-09 37.2 0.1 2.1e-09 37.1 0.1 1.0 1 0 0 1 1 1 1 Prophage CP4-57 regulatory protein (AlpA) HTH_17 PF12728.7 EHT98859.1 - 3.3e-07 30.4 0.0 3.7e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_1_2 PF13022.6 EHT98859.1 - 0.014 15.5 0.0 0.014 15.5 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_28 PF13518.6 EHT98859.1 - 0.039 14.1 0.1 0.11 12.6 0.0 1.7 2 1 1 3 3 3 0 Helix-turn-helix domain MerR PF00376.23 EHT98859.1 - 0.044 13.6 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 MerR family regulatory protein HTH_Tnp_4 PF13613.6 EHT98859.1 - 0.046 13.4 0.0 0.25 11.1 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease MerR_1 PF13411.6 EHT98859.1 - 0.087 12.9 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 MerR HTH family regulatory protein HTH_23 PF13384.6 EHT98859.1 - 0.15 11.9 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain DDE_Tnp_IS66 PF03050.14 EHT98860.1 - 6e-98 327.8 3.5 3.5e-97 325.3 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT98860.1 - 3.3e-16 59.2 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT98860.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT98860.1 - 8.7e-11 42.4 9.0 1.9e-10 41.4 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Phage_HK97_TLTM PF06120.11 EHT98860.1 - 0.029 13.5 0.7 0.056 12.6 0.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Exonuc_VII_L PF02601.15 EHT98860.1 - 0.034 13.7 2.1 0.044 13.4 0.9 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit UME PF08064.13 EHT98860.1 - 0.037 13.9 0.4 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain FUSC PF04632.12 EHT98860.1 - 0.067 11.7 7.7 0.1 11.1 7.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Csm1_N PF18504.1 EHT98860.1 - 0.13 12.6 3.4 0.86 10.0 0.2 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Tho2 PF11262.8 EHT98860.1 - 0.17 11.0 0.3 0.28 10.4 0.3 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DHR10 PF18595.1 EHT98860.1 - 0.18 11.9 10.2 0.31 11.1 10.2 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain LXG PF04740.12 EHT98860.1 - 0.28 10.8 2.4 0.86 9.3 0.3 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHT98860.1 - 0.28 10.9 10.4 0.45 10.3 10.4 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HHH_8 PF14716.6 EHT98860.1 - 0.34 11.3 4.0 0.56 10.6 1.9 2.4 2 1 0 2 2 2 0 Helix-hairpin-helix domain Zn-ribbon_8 PF09723.10 EHT98860.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain TSNAXIP1_N PF15739.5 EHT98860.1 - 0.46 10.9 3.2 0.99 9.8 3.2 1.5 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus FAM184 PF15665.5 EHT98860.1 - 0.49 10.1 7.3 0.78 9.5 7.3 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B TMPIT PF07851.13 EHT98860.1 - 0.78 8.9 2.7 1.2 8.4 2.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein CREPT PF16566.5 EHT98860.1 - 2.4 8.3 8.3 1.1 9.5 5.2 1.8 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour HAUS-augmin3 PF14932.6 EHT98860.1 - 2.6 7.6 7.4 5.8 6.4 7.4 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 SlyX PF04102.12 EHT98860.1 - 8.2 7.1 8.7 17 6.1 2.1 3.0 1 1 1 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHT98861.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHT98862.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT98862.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT98862.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT98862.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix Phage_integrase PF00589.22 EHT98863.1 - 6.7e-15 55.3 0.0 1.4e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family Arm-DNA-bind_3 PF13356.6 EHT98863.1 - 1.1e-05 25.7 1.6 6.6e-05 23.2 0.2 2.6 3 0 0 3 3 3 1 Arm DNA-binding domain Phage_int_SAM_3 PF14659.6 EHT98863.1 - 0.0098 16.1 0.1 0.038 14.3 0.1 2.0 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain DUF2326 PF10088.9 EHT98864.1 - 2.4e-19 69.5 4.4 9.6e-19 67.5 4.4 2.1 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2326) MtrG PF04210.13 EHT98864.1 - 2.1 8.3 5.1 7.1 6.6 0.0 3.4 4 0 0 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF2959 PF11172.8 EHT98867.1 - 0.0061 16.7 1.6 0.011 15.9 1.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2959) DUF2891 PF11199.8 EHT98867.1 - 0.083 11.8 1.4 0.12 11.4 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2891) MOR2-PAG1_C PF14225.6 EHT98867.1 - 0.11 12.3 0.2 0.17 11.7 0.2 1.2 1 0 0 1 1 1 0 Cell morphogenesis C-terminal EVC2_like PF12297.8 EHT98867.1 - 0.44 9.2 6.4 0.62 8.7 6.4 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein FUSC PF04632.12 EHT98867.1 - 2 6.9 8.2 2.6 6.5 8.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ogr_Delta PF04606.12 EHT98868.1 - 1.5e-15 56.9 3.8 2e-15 56.5 3.8 1.2 1 0 0 1 1 1 1 Ogr/Delta-like zinc finger zf-GRF PF06839.12 EHT98868.1 - 0.0012 18.9 1.8 0.0019 18.3 1.8 1.3 1 0 0 1 1 1 1 GRF zinc finger Zn_ribbon_recom PF13408.6 EHT98868.1 - 0.013 16.0 0.4 0.013 16.0 0.4 1.6 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-tcix PF14952.6 EHT98868.1 - 0.015 14.9 1.7 2 8.1 0.1 2.3 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding Mu-like_Com PF10122.9 EHT98868.1 - 0.023 14.2 0.1 0.04 13.4 0.1 1.4 1 0 0 1 1 1 0 Mu-like prophage protein Com zf-C2H2 PF00096.26 EHT98868.1 - 0.13 12.8 3.5 4.1 8.1 0.6 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type DNA_ligase_ZBD PF03119.16 EHT98868.1 - 0.47 10.5 5.0 3.3 7.8 5.0 2.3 1 1 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain DUF4510 PF14971.6 EHT98869.1 - 0.033 14.5 3.8 0.052 13.9 3.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) DUF5542 PF17696.1 EHT98869.1 - 0.19 11.9 1.3 0.34 11.0 1.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5542) DUF927 PF06048.11 EHT98870.1 - 1.8e-98 329.7 0.2 2.8e-98 329.1 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF927) Prim_Zn_Ribbon PF08273.12 EHT98870.1 - 5.1e-16 58.7 9.7 5.1e-16 58.7 9.7 2.7 3 0 0 3 3 3 1 Zinc-binding domain of primase-helicase Toprim_3 PF13362.6 EHT98870.1 - 4.6e-13 49.4 1.1 2.5e-12 47.0 0.1 2.7 2 0 0 2 2 2 1 Toprim domain Toprim_4 PF13662.6 EHT98870.1 - 0.00082 19.8 0.0 0.003 18.0 0.0 1.9 1 0 0 1 1 1 1 Toprim domain TF_Zn_Ribbon PF08271.12 EHT98870.1 - 0.0029 17.1 1.7 0.0061 16.0 1.7 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.7 EHT98870.1 - 0.0034 17.3 1.0 0.0092 15.9 1.0 1.8 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Toprim_2 PF13155.6 EHT98870.1 - 0.009 16.4 0.0 0.023 15.1 0.0 1.8 1 0 0 1 1 1 1 Toprim-like zf-RRN7 PF11781.8 EHT98870.1 - 0.062 13.0 4.0 0.26 11.0 4.0 2.0 1 1 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DUF5375 PF17345.2 EHT98871.1 - 6.8e-14 51.6 0.1 9.1e-14 51.2 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5375) DUF4222 PF13973.6 EHT98873.1 - 0.014 15.0 0.0 0.086 12.5 0.0 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4222) Phage_integrase PF00589.22 EHT98874.1 - 1.7e-15 57.3 0.0 3.2e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family Arm-DNA-bind_3 PF13356.6 EHT98874.1 - 1.9e-12 47.4 0.3 1.5e-11 44.5 0.3 2.2 2 0 0 2 2 2 1 Arm DNA-binding domain Phage_int_SAM_3 PF14659.6 EHT98874.1 - 0.0019 18.4 1.6 0.0064 16.7 0.2 2.6 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain YicC_N PF03755.13 EHT98875.1 - 1.5e-43 148.9 1.3 4.1e-43 147.4 0.0 2.2 2 1 0 2 2 2 1 YicC-like family, N-terminal region DUF1732 PF08340.11 EHT98875.1 - 9.7e-35 118.4 6.5 2.3e-34 117.2 6.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1732) DDE_Tnp_IS66 PF03050.14 EHT98875.1 - 0.029 13.9 0.8 0.029 13.9 0.8 1.8 2 0 0 2 2 2 0 Transposase IS66 family Baculo_PEP_C PF04513.12 EHT98875.1 - 0.37 10.8 7.1 1.6e+02 2.2 7.1 2.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 EHT98875.1 - 1.4 9.5 5.4 3.8 8.0 1.1 3.2 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3574 PF12098.8 EHT98876.1 - 9.6e-37 124.9 0.0 1.1e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3574) MLTD_N PF06474.12 EHT98876.1 - 0.058 13.6 0.6 0.058 13.6 0.6 2.1 2 0 0 2 2 2 0 MltD lipid attachment motif Nucleos_tra2_C PF07662.13 EHT98877.1 - 5.6e-60 202.7 13.6 5.6e-60 202.7 13.6 1.9 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 EHT98877.1 - 4.6e-16 59.2 6.9 4.6e-16 59.2 6.9 4.3 4 1 1 5 5 5 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 EHT98877.1 - 1.7e-06 28.2 3.7 1.7e-06 28.2 3.7 3.4 4 0 0 4 4 4 1 Nucleoside recognition RNase_PH PF01138.21 EHT98878.1 - 1.5e-23 83.8 0.0 2.6e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EHT98878.1 - 4.4e-11 42.6 0.4 7.6e-11 41.9 0.4 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 BrnA_antitoxin PF14384.6 EHT98878.1 - 0.18 12.3 0.1 34 5.0 0.0 2.4 2 0 0 2 2 2 0 BrnA antitoxin of type II toxin-antitoxin system Pribosyltran PF00156.27 EHT98879.1 - 1.2e-11 44.4 0.1 1.7e-11 43.9 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain TetR_N PF00440.23 EHT98880.1 - 1.3e-08 34.5 0.0 2.2e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 EHT98880.1 - 0.0051 17.0 1.7 0.0092 16.2 0.4 1.9 2 0 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal TetR_C_15 PF17918.1 EHT98880.1 - 0.0067 17.2 0.6 0.24 12.2 0.0 2.5 2 2 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_16 PF17920.1 EHT98880.1 - 0.023 14.9 0.5 6.6 7.0 0.0 3.0 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain HTH_AsnC-type PF13404.6 EHT98880.1 - 0.043 13.7 0.2 0.11 12.4 0.2 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain DUF390 PF04094.14 EHT98880.1 - 0.12 10.7 0.2 0.11 10.7 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF390) Seadorna_VP6 PF07407.11 EHT98880.1 - 0.13 11.2 0.2 0.28 10.1 0.1 1.5 1 1 0 1 1 1 0 Seadornavirus VP6 protein dUTPase PF00692.19 EHT98881.1 - 2.5e-41 140.4 0.0 2.8e-41 140.2 0.0 1.0 1 0 0 1 1 1 1 dUTPase DFP PF04127.15 EHT98882.1 - 2.6e-74 249.1 1.8 2.6e-74 249.1 1.8 2.1 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein Flavoprotein PF02441.19 EHT98882.1 - 4.1e-44 150.1 0.1 9e-44 149.0 0.1 1.6 2 0 0 2 2 2 1 Flavoprotein PALP PF00291.25 EHT98882.1 - 0.012 15.0 0.3 0.024 14.0 0.3 1.5 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme RadC PF04002.15 EHT98883.1 - 3.9e-43 146.3 0.1 5.5e-43 145.8 0.1 1.2 1 0 0 1 1 1 1 RadC-like JAB domain Prok-JAB PF14464.6 EHT98883.1 - 0.0015 18.3 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Ribosomal_L28 PF00830.19 EHT98884.1 - 1.5e-25 89.1 1.9 1.7e-25 88.9 1.9 1.0 1 0 0 1 1 1 1 Ribosomal L28 family Ribosomal_L33 PF00471.20 EHT98885.1 - 9.2e-19 67.6 0.9 1e-18 67.5 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L33 Fapy_DNA_glyco PF01149.24 EHT98886.1 - 2.8e-31 108.5 0.0 5.1e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 EHT98886.1 - 1e-27 95.9 0.0 1.8e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain zf-FPG_IleRS PF06827.14 EHT98886.1 - 4.2e-10 39.3 6.3 7.2e-10 38.5 6.3 1.4 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS Auto_anti-p27 PF06677.12 EHT98886.1 - 0.007 16.5 0.8 0.012 15.7 0.8 1.4 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) CTP_transf_like PF01467.26 EHT98887.1 - 4.6e-21 75.5 0.0 5.3e-21 75.3 0.0 1.0 1 0 0 1 1 1 1 Cytidylyltransferase-like Citrate_ly_lig PF08218.11 EHT98887.1 - 1.4e-05 24.8 0.0 1.7e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Citrate lyase ligase C-terminal domain Glycos_transf_2 PF00535.26 EHT98888.1 - 1.5e-16 60.6 0.0 2.2e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.6 EHT98888.1 - 6.8e-06 26.5 0.1 2.6e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EHT98888.1 - 1.2e-05 25.4 0.0 1.4e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EHT98888.1 - 0.00087 18.8 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_N PF04413.16 EHT98889.1 - 7.1e-68 227.7 0.0 2e-67 226.3 0.0 1.7 2 0 0 2 2 2 1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Glycos_transf_1 PF00534.20 EHT98889.1 - 8.8e-05 22.1 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EHT98890.1 - 1.2e-28 99.8 0.0 2.1e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EHT98890.1 - 3.5e-22 79.3 0.0 7.6e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EHT98890.1 - 6.3e-18 65.4 0.1 1.2e-17 64.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EHT98890.1 - 5.8e-07 30.1 0.1 1.6e-06 28.7 0.1 1.8 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EHT98890.1 - 1.6e-06 28.4 0.0 4.2e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_9 PF01075.17 EHT98891.1 - 5.7e-52 176.5 0.0 7.4e-52 176.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) Tugs PF17840.1 EHT98891.1 - 0.00065 19.8 0.4 0.002 18.3 0.3 1.9 2 0 0 2 2 2 1 Tethering Ubl4a to BAGS domain PS_pyruv_trans PF04230.13 EHT98891.1 - 0.079 12.9 0.0 7.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide pyruvyl transferase Glycos_transf_2 PF00535.26 EHT98892.1 - 1.3e-29 103.2 0.1 5.3e-29 101.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EHT98892.1 - 2.8e-12 47.0 0.2 1.3e-11 44.9 0.1 2.1 1 1 1 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EHT98892.1 - 1.7e-09 37.6 0.0 2.8e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_9 PF01075.17 EHT98893.1 - 5.2e-05 22.7 0.0 6.7e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) DUF2616 PF11077.8 EHT98893.1 - 0.054 13.2 0.0 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2616) DUF383 PF04063.14 EHT98893.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF383) HN PF00423.19 EHT98894.1 - 0.19 10.5 0.0 0.33 9.7 0.0 1.3 1 0 0 1 1 1 0 Haemagglutinin-neuraminidase Glycos_transf_1 PF00534.20 EHT98895.1 - 1.2e-26 93.3 0.0 2.3e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EHT98895.1 - 6.4e-22 78.4 0.0 1.3e-21 77.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EHT98895.1 - 7.2e-14 52.1 0.0 1.3e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EHT98895.1 - 0.00063 20.2 0.0 0.001 19.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EHT98895.1 - 0.022 15.1 0.0 0.049 14.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 DDE_3 PF13358.6 EHT98896.1 - 4.4e-23 81.6 0.0 5.1e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_IS66 PF03050.14 EHT98897.1 - 2.7e-97 325.7 4.0 1.2e-96 323.5 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT98897.1 - 3.3e-16 59.2 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT98897.1 - 5.9e-14 52.2 1.3 1.4e-13 51.0 1.3 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT98897.1 - 8.8e-11 42.4 9.0 1.9e-10 41.4 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Phage_HK97_TLTM PF06120.11 EHT98897.1 - 0.011 15.0 0.8 0.021 14.0 0.8 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHT98897.1 - 0.02 15.2 4.2 0.084 13.2 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain UME PF08064.13 EHT98897.1 - 0.033 14.1 0.3 20 5.1 0.0 3.1 2 1 1 3 3 3 0 UME (NUC010) domain Exonuc_VII_L PF02601.15 EHT98897.1 - 0.035 13.7 2.4 0.039 13.5 0.8 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Troponin PF00992.20 EHT98897.1 - 0.044 14.1 2.8 0.078 13.3 2.8 1.3 1 0 0 1 1 1 0 Troponin Tho2 PF11262.8 EHT98897.1 - 0.049 12.8 0.6 0.081 12.1 0.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FUSC PF04632.12 EHT98897.1 - 0.05 12.2 7.5 0.079 11.5 7.5 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family FAM184 PF15665.5 EHT98897.1 - 0.052 13.3 8.0 0.082 12.7 8.0 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B HalX PF08663.10 EHT98897.1 - 0.13 12.6 2.4 0.34 11.3 2.4 1.7 1 0 0 1 1 1 0 HalX domain LXG PF04740.12 EHT98897.1 - 0.14 11.8 2.8 0.35 10.5 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHT98897.1 - 0.19 11.5 11.1 0.31 10.8 11.1 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DHR10 PF18595.1 EHT98897.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF1192 PF06698.11 EHT98897.1 - 0.54 10.3 5.3 3.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHT98897.1 - 0.82 8.9 3.0 1.2 8.3 3.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHT98897.1 - 2 8.0 8.1 4.3 6.8 8.1 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHT98897.1 - 4.2 7.7 8.6 8.7 6.7 8.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CREPT PF16566.5 EHT98897.1 - 5.9 7.0 8.7 2.7 8.1 5.6 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour SlyX PF04102.12 EHT98897.1 - 9.8 6.9 9.0 18 6.1 2.3 3.0 1 1 1 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHT98898.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHT98899.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT98899.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT98899.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT98899.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix HTH_32 PF13565.6 EHT98900.1 - 2.1e-09 37.8 0.3 4.1e-09 36.9 0.3 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHT98900.1 - 2.6e-09 36.6 0.0 2.4e-07 30.3 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_33 PF13592.6 EHT98900.1 - 4.3e-07 29.5 1.1 8.7e-07 28.5 0.3 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_29 PF13551.6 EHT98900.1 - 6.4e-07 29.3 0.3 5e-06 26.4 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHT98900.1 - 0.00018 21.5 0.1 0.0057 16.8 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHT98900.1 - 0.021 14.6 0.1 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHT98900.1 - 0.029 14.9 0.1 0.05 14.1 0.1 1.4 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 HTH_Tnp_ISL3 PF13542.6 EHT98900.1 - 0.068 12.6 0.4 1.2 8.6 0.2 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_Tnp_Tc3_2 PF01498.18 EHT98900.1 - 0.11 12.8 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Transposase Epimerase PF01370.21 EHT98901.1 - 2.5e-44 151.6 0.0 3.2e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EHT98901.1 - 3.8e-25 89.0 0.1 1e-24 87.6 0.1 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EHT98901.1 - 8.4e-11 41.5 0.0 2.5e-10 39.9 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 EHT98901.1 - 9.5e-09 34.6 0.0 1.3e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EHT98901.1 - 5.4e-06 25.8 0.0 0.00045 19.5 0.0 2.4 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 EHT98901.1 - 1.3e-05 24.5 0.0 0.048 12.8 0.0 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein KR PF08659.10 EHT98901.1 - 0.0019 18.1 0.1 0.037 13.9 0.1 2.3 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 EHT98901.1 - 0.2 11.1 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase TrkA_N PF02254.18 EHT98901.1 - 0.22 11.8 0.1 0.42 10.9 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Glyco_transf_9 PF01075.17 EHT98902.1 - 5.6e-81 271.5 0.0 7.7e-81 271.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) PS_pyruv_trans PF04230.13 EHT98902.1 - 0.018 15.0 0.0 5.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide pyruvyl transferase Glyco_transf_9 PF01075.17 EHT98903.1 - 4.2e-75 252.3 0.1 5.5e-75 251.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) Epimerase_2 PF02350.19 EHT98903.1 - 0.11 11.4 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Glyco_transf_9 PF01075.17 EHT98904.1 - 1.9e-17 63.5 0.0 2.9e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) Glyco_transf_9 PF01075.17 EHT98905.1 - 2.5e-22 79.4 0.0 3.7e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) PS_pyruv_trans PF04230.13 EHT98905.1 - 0.0012 18.9 0.4 1.6 8.6 0.0 2.2 2 0 0 2 2 2 2 Polysaccharide pyruvyl transferase Polysacc_deac_2 PF04748.13 EHT98906.1 - 6.7e-75 250.9 0.5 8e-75 250.7 0.5 1.1 1 0 0 1 1 1 1 Divergent polysaccharide deacetylase Peptidase_M23 PF01551.22 EHT98907.1 - 3.6e-27 94.4 0.1 8.3e-27 93.2 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M23 Spc7 PF08317.11 EHT98907.1 - 0.11 11.3 45.9 0.45 9.3 15.7 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 EHT98907.1 - 4 7.5 27.9 1 9.4 8.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Peptidase_M3_N PF08439.10 EHT98907.1 - 5.3 7.4 7.1 25 5.2 0.3 3.1 3 0 0 3 3 3 0 Oligopeptidase F DUF1043 PF06295.12 EHT98907.1 - 6.5 6.8 36.6 1.1 9.3 15.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Fez1 PF06818.15 EHT98907.1 - 7.5 6.9 53.2 1.7 9.1 28.1 2.1 1 1 1 2 2 2 0 Fez1 AAA_13 PF13166.6 EHT98907.1 - 8.2 4.9 32.5 1.7 7.2 15.3 2.1 2 0 0 2 2 2 0 AAA domain Rhodanese PF00581.20 EHT98908.1 - 8e-19 68.1 0.0 1.1e-18 67.7 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain MSP1a PF11670.8 EHT98908.1 - 0.1 11.9 1.9 0.17 11.1 0.3 1.8 1 1 1 2 2 2 0 Major surface protein 1a (MSP1a) Glutaredoxin PF00462.24 EHT98909.1 - 1.4e-25 89.2 0.0 1.8e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 EHT98909.1 - 7.6e-09 35.9 0.0 8.6e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EHT98909.1 - 2.5e-07 30.9 0.0 3e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_3 PF13192.6 EHT98909.1 - 1.1e-05 25.4 0.0 1.5e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain DUF836 PF05768.14 EHT98909.1 - 0.00018 21.8 0.0 0.0002 21.7 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_4 PF13462.6 EHT98909.1 - 0.0034 17.6 0.4 1.8 8.7 0.0 2.0 1 1 1 2 2 2 2 Thioredoxin SH3BGR PF04908.15 EHT98909.1 - 0.022 14.9 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein GST_N PF02798.20 EHT98909.1 - 0.044 14.1 0.0 0.049 14.0 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DSBA PF01323.20 EHT98909.1 - 0.049 13.4 0.1 6.9 6.4 0.0 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 EHT98909.1 - 0.15 12.6 0.3 0.39 11.2 0.3 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain SecB PF02556.14 EHT98910.1 - 5.1e-58 195.0 0.2 6.2e-58 194.7 0.2 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit SecB NAD_Gly3P_dh_C PF07479.14 EHT98911.1 - 3.9e-52 176.3 1.1 6.3e-52 175.6 1.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 EHT98911.1 - 1.2e-48 165.0 0.0 1.7e-48 164.6 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 EHT98911.1 - 4.2e-10 39.5 0.0 7.2e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 EHT98911.1 - 0.00025 21.3 0.0 0.00072 19.7 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EHT98911.1 - 0.00055 20.5 0.0 0.0025 18.4 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent GIDA PF01134.22 EHT98911.1 - 0.00069 18.8 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.14 EHT98911.1 - 0.0022 17.6 0.0 0.013 15.1 0.0 2.3 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 EHT98911.1 - 0.0062 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.9 EHT98911.1 - 0.0072 16.2 0.1 0.019 14.8 0.0 1.8 2 0 0 2 2 2 1 Rossmann-like domain NAD_binding_8 PF13450.6 EHT98911.1 - 0.015 15.5 0.1 0.06 13.6 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EHT98911.1 - 0.025 13.8 0.0 0.049 12.9 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EHT98911.1 - 0.025 14.8 0.0 0.15 12.4 0.0 2.2 3 0 0 3 3 3 0 TrkA-N domain SATase_N PF06426.14 EHT98912.1 - 5.9e-40 135.9 0.2 8.7e-40 135.3 0.2 1.3 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep PF00132.24 EHT98912.1 - 1.2e-11 43.8 6.4 6.6e-10 38.3 0.9 2.9 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EHT98912.1 - 5e-05 23.0 5.6 0.00058 19.5 1.1 2.5 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Gly-zipper_OmpA PF13436.6 EHT98912.1 - 3.4 7.5 7.3 1.1 9.1 3.6 2.2 2 1 0 2 2 2 0 Glycine-zipper domain SpoU_methylase PF00588.19 EHT98913.1 - 1.2e-33 116.3 0.0 1.3e-33 116.2 0.0 1.0 1 0 0 1 1 1 1 SpoU rRNA Methylase family Malate_DH PF12434.8 EHT98913.1 - 0.0066 16.4 0.9 0.0082 16.1 0.0 1.7 2 0 0 2 2 2 1 Malate dehydrogenase enzyme HATPase_c PF02518.26 EHT98914.1 - 4e-21 75.6 0.0 2.3e-20 73.2 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EHT98914.1 - 3.1e-14 52.7 4.9 7.4e-14 51.5 3.6 2.3 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain CpxA_peri PF16527.5 EHT98914.1 - 1.2e-10 41.9 0.0 2.5e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Two-component sensor protein CpxA, periplasmic domain HAMP PF00672.25 EHT98914.1 - 1.6e-10 41.1 0.4 7e-10 39.1 0.0 2.3 2 1 0 2 2 2 1 HAMP domain HATPase_c_3 PF13589.6 EHT98914.1 - 5.1e-05 23.1 0.0 9e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EHT98914.1 - 0.0003 20.7 0.0 0.00057 19.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Response_reg PF00072.24 EHT98915.1 - 1.3e-30 105.8 0.3 2.4e-30 105.0 0.2 1.5 2 0 0 2 2 2 1 Response regulator receiver domain Trans_reg_C PF00486.28 EHT98915.1 - 3e-21 75.3 0.4 7.6e-21 74.0 0.1 1.8 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal FleQ PF06490.11 EHT98915.1 - 0.0049 17.2 0.2 0.0079 16.6 0.1 1.4 1 1 0 1 1 1 1 Flagellar regulatory protein FleQ DUF2325 PF10087.9 EHT98915.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) BRCT_3 PF18428.1 EHT98915.1 - 0.2 11.7 0.0 0.45 10.6 0.0 1.6 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain LTXXQ PF07813.12 EHT98916.1 - 2.1e-17 63.8 14.2 2.1e-17 63.8 14.2 1.5 2 0 0 2 2 2 1 LTXXQ motif family protein Metal_resist PF13801.6 EHT98916.1 - 2.6e-06 27.6 15.2 0.00051 20.2 8.9 2.2 1 1 1 2 2 2 2 Heavy-metal resistance NTPase_1 PF03266.15 EHT98916.1 - 0.015 15.2 0.0 0.033 14.1 0.0 1.5 1 1 0 1 1 1 0 NTPase KIF1B PF12423.8 EHT98916.1 - 0.056 13.9 0.2 13 6.3 0.2 2.5 2 0 0 2 2 2 0 Kinesin protein 1B Sa_NUDIX PF18167.1 EHT98916.1 - 0.068 13.0 1.4 0.077 12.8 0.3 1.7 1 1 1 2 2 2 0 SMODS-associated NUDIX domain DUF3106 PF11304.8 EHT98916.1 - 0.075 13.5 12.4 0.69 10.4 4.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3106) DUF4200 PF13863.6 EHT98916.1 - 0.41 11.0 8.0 0.1 13.0 3.4 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) CSRNP_N PF16019.5 EHT98916.1 - 0.43 10.5 4.7 0.78 9.6 4.7 1.5 1 1 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Arg_decarbox_C PF17944.1 EHT98916.1 - 2 9.0 5.9 0.62 10.7 1.6 2.2 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension XET_C PF06955.12 EHT98916.1 - 3.1 7.7 6.7 6 6.8 0.3 3.1 2 1 1 3 3 3 0 Xyloglucan endo-transglycosylase (XET) C-terminus DUF2680 PF10925.8 EHT98916.1 - 7.1 6.7 9.2 26 4.9 2.8 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2680) KGG PF10685.9 EHT98917.1 - 4.9e-15 55.2 15.8 1e-07 32.0 4.2 2.2 2 0 0 2 2 2 2 Stress-induced bacterial acidophilic repeat motif Cation_efflux PF01545.21 EHT98918.1 - 5.8e-42 143.7 17.4 7e-42 143.4 17.4 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EHT98918.1 - 6.4e-27 93.5 0.1 9.8e-27 92.9 0.1 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF4271 PF14093.6 EHT98918.1 - 0.02 14.8 0.3 0.02 14.8 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) KAP_NTPase PF07693.14 EHT98918.1 - 0.22 10.8 0.1 0.3 10.3 0.1 1.3 1 0 0 1 1 1 0 KAP family P-loop domain PFK PF00365.20 EHT98919.1 - 1.8e-108 362.2 0.5 2.2e-108 361.9 0.5 1.1 1 0 0 1 1 1 1 Phosphofructokinase NAD_kinase PF01513.21 EHT98919.1 - 0.0022 17.3 0.1 0.0032 16.7 0.1 1.2 1 0 0 1 1 1 1 ATP-NAD kinase FlgM PF04316.13 EHT98919.1 - 0.15 12.5 0.2 1.1 9.6 0.0 2.2 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM SBP_bac_11 PF13531.6 EHT98920.1 - 1.4e-44 152.5 0.1 1.7e-44 152.3 0.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 EHT98920.1 - 5.9e-16 59.3 4.8 6.3e-16 59.2 2.6 1.8 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 EHT98920.1 - 5.1e-10 39.2 0.2 7.4e-10 38.6 0.2 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 EHT98920.1 - 3.3e-06 27.1 0.8 5.3e-06 26.5 0.8 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein PBP_like PF12727.7 EHT98920.1 - 5.7e-05 22.3 0.0 0.00011 21.4 0.0 1.4 1 0 0 1 1 1 1 PBP superfamily domain TIM PF00121.18 EHT98921.1 - 2.4e-94 315.3 0.2 2.7e-94 315.1 0.2 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase DUF1454 PF07305.12 EHT98923.1 - 7.5e-80 266.9 0.0 8.4e-80 266.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1454) DUF805 PF05656.14 EHT98924.1 - 1.1e-17 64.4 5.9 1.5e-17 63.9 5.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF805) DUF4184 PF13803.6 EHT98924.1 - 0.042 13.5 1.2 0.053 13.2 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4184) TspO_MBR PF03073.15 EHT98924.1 - 0.079 13.0 8.1 0.11 12.5 8.1 1.3 1 0 0 1 1 1 0 TspO/MBR family Yip1 PF04893.17 EHT98924.1 - 0.36 10.5 13.7 2.5 7.8 13.7 2.1 1 1 0 1 1 1 0 Yip1 domain NAD_binding_1 PF00175.21 EHT98925.1 - 1.8e-17 63.9 0.0 2.8e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EHT98925.1 - 1.1e-08 35.3 0.0 2.3e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain MFS_1 PF07690.16 EHT98926.1 - 4.4e-34 118.0 52.0 4.4e-34 118.0 52.0 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EHT98926.1 - 0.0011 17.5 6.8 0.0018 16.8 6.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2530 PF10745.9 EHT98926.1 - 0.016 15.4 0.4 0.016 15.4 0.4 4.2 5 1 1 6 6 6 0 Protein of unknown function (DUF2530) FBPase_glpX PF03320.13 EHT98927.1 - 1.6e-130 434.5 7.1 1.8e-130 434.3 7.1 1.0 1 0 0 1 1 1 1 Bacterial fructose-1,6-bisphosphatase, glpX-encoded YejG PF13989.6 EHT98927.1 - 0.19 12.2 0.0 0.45 11.0 0.0 1.6 1 0 0 1 1 1 0 YejG-like protein FGGY_N PF00370.21 EHT98928.1 - 6.5e-89 297.7 0.4 9.1e-89 297.2 0.4 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EHT98928.1 - 1.3e-62 211.0 1.5 3.1e-62 209.8 1.1 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain MIP PF00230.20 EHT98929.1 - 8.5e-70 235.0 12.4 1.1e-69 234.6 12.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein Clathrin-link PF09268.10 EHT98929.1 - 0.58 9.6 1.6 11 5.5 0.0 2.8 3 0 0 3 3 3 0 Clathrin, heavy-chain linker DUF2613 PF11021.8 EHT98929.1 - 0.6 10.3 0.1 0.6 10.3 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) ZapB PF06005.12 EHT98930.1 - 3.8e-27 94.5 13.9 4.3e-27 94.4 13.9 1.0 1 0 0 1 1 1 1 Cell division protein ZapB PspA_IM30 PF04012.12 EHT98930.1 - 0.00066 19.3 8.0 0.00072 19.2 8.0 1.0 1 0 0 1 1 1 1 PspA/IM30 family CtIP_N PF10482.9 EHT98930.1 - 0.0014 18.6 10.4 0.09 12.8 3.7 2.0 1 1 1 2 2 2 2 Tumour-suppressor protein CtIP N-terminal domain KASH_CCD PF14662.6 EHT98930.1 - 0.0026 17.6 10.4 0.0027 17.6 10.4 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Leu_zip PF15294.6 EHT98930.1 - 0.0027 17.3 5.8 0.0032 17.0 5.8 1.2 1 0 0 1 1 1 1 Leucine zipper Tropomyosin_1 PF12718.7 EHT98930.1 - 0.012 15.8 10.1 0.014 15.6 10.1 1.1 1 0 0 1 1 1 0 Tropomyosin like ADIP PF11559.8 EHT98930.1 - 0.017 15.2 6.3 0.02 15.0 6.3 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 EHT98930.1 - 0.023 15.3 11.5 0.18 12.5 11.5 1.9 1 1 0 1 1 1 0 Initiation control protein YabA UPF0242 PF06785.11 EHT98930.1 - 0.024 14.7 8.3 0.027 14.6 8.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DHR10 PF18595.1 EHT98930.1 - 0.025 14.6 10.5 0.033 14.2 10.5 1.1 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Seryl_tRNA_N PF02403.22 EHT98930.1 - 0.032 14.5 7.1 0.042 14.1 7.1 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain GIT_CC PF16559.5 EHT98930.1 - 0.036 13.9 8.1 0.081 12.8 2.2 2.2 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor HemX PF04375.14 EHT98930.1 - 0.037 13.3 5.7 0.038 13.3 5.7 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4156 PF13698.6 EHT98930.1 - 0.037 14.4 0.5 0.04 14.2 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4156) TMF_TATA_bd PF12325.8 EHT98930.1 - 0.045 14.0 7.7 0.053 13.7 7.7 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Jnk-SapK_ap_N PF09744.9 EHT98930.1 - 0.052 13.8 8.3 0.058 13.6 8.3 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Herpes_UL6 PF01763.16 EHT98930.1 - 0.062 11.8 3.5 0.066 11.7 3.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Occludin_ELL PF07303.13 EHT98930.1 - 0.071 13.8 1.9 0.081 13.6 1.9 1.2 1 0 0 1 1 1 0 Occludin homology domain DUF2968 PF11180.8 EHT98930.1 - 0.089 12.4 7.8 0.1 12.2 7.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) K-box PF01486.17 EHT98930.1 - 0.098 12.8 10.1 2 8.6 2.5 2.5 1 1 1 2 2 2 0 K-box region Uso1_p115_C PF04871.13 EHT98930.1 - 0.11 12.8 8.1 0.13 12.6 8.1 1.0 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3450 PF11932.8 EHT98930.1 - 0.12 11.7 6.8 0.13 11.5 6.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) V_ATPase_I PF01496.19 EHT98930.1 - 0.16 9.8 3.9 0.18 9.7 3.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family dCache_2 PF08269.11 EHT98930.1 - 0.2 10.8 4.4 0.23 10.6 4.4 1.0 1 0 0 1 1 1 0 Cache domain HALZ PF02183.18 EHT98930.1 - 0.2 11.9 10.6 1.2 9.4 0.1 2.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF2205 PF10224.9 EHT98930.1 - 0.31 11.1 8.6 1 9.4 4.7 2.1 1 1 1 2 2 2 0 Short coiled-coil protein Cep57_CLD_2 PF14197.6 EHT98930.1 - 0.4 10.8 10.4 1.2 9.3 10.4 1.7 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 APG6_N PF17675.1 EHT98930.1 - 0.47 11.0 11.8 0.55 10.8 11.8 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region NUDE_C PF04880.13 EHT98930.1 - 0.57 10.6 9.9 2.2 8.7 9.9 1.8 1 1 0 1 1 1 0 NUDE protein, C-terminal conserved region FlaC_arch PF05377.11 EHT98930.1 - 0.59 10.6 5.7 3.5 8.1 3.1 2.1 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) CorA PF01544.18 EHT98930.1 - 0.59 9.4 5.0 0.33 10.2 2.7 1.6 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein bZIP_1 PF00170.21 EHT98930.1 - 0.92 9.7 10.2 0.98 9.6 2.2 2.4 1 1 2 3 3 3 0 bZIP transcription factor TSC22 PF01166.18 EHT98930.1 - 1.1 9.6 9.3 0.99 9.8 3.8 2.4 1 1 1 2 2 2 0 TSC-22/dip/bun family Spc24 PF08286.11 EHT98930.1 - 1.5 9.1 9.6 6.1 7.1 9.6 1.8 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 SlyX PF04102.12 EHT98930.1 - 2.4 8.8 9.2 12 6.6 9.2 2.1 1 1 0 1 1 1 0 SlyX DivIC PF04977.15 EHT98930.1 - 3.1 7.6 10.8 1.6 8.5 5.2 2.1 1 1 1 2 2 2 0 Septum formation initiator RraA-like PF03737.15 EHT98931.1 - 1.3e-35 122.8 0.1 1.5e-35 122.6 0.1 1.0 1 0 0 1 1 1 1 Aldolase/RraA baeRF_family5 PF18846.1 EHT98931.1 - 0.086 13.0 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 5 Lactamase_B PF00753.27 EHT98931.1 - 0.18 11.8 0.7 17 5.3 0.1 2.1 1 1 0 2 2 2 0 Metallo-beta-lactamase superfamily AAA_2 PF07724.14 EHT98932.1 - 1.8e-49 168.1 0.3 1.7e-40 139.0 0.1 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 EHT98932.1 - 8.9e-16 58.5 0.0 1.3e-06 28.9 0.0 3.1 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EHT98932.1 - 1.9e-07 31.2 0.1 1e-05 25.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EHT98932.1 - 5.2e-07 30.0 0.0 0.00019 21.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain ClpB_D2-small PF10431.9 EHT98932.1 - 4.4e-06 26.7 0.4 2.2e-05 24.4 0.0 2.4 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein MCM PF00493.23 EHT98932.1 - 2.4e-05 23.6 0.2 0.0011 18.1 0.0 2.3 2 0 0 2 2 2 1 MCM P-loop domain Mg_chelatase PF01078.21 EHT98932.1 - 8.8e-05 22.0 0.3 0.0042 16.5 0.0 3.1 3 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 EHT98932.1 - 0.0005 20.5 0.3 0.0016 18.8 0.1 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EHT98932.1 - 0.00081 19.9 0.0 0.0032 18.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EHT98932.1 - 0.0011 18.7 0.1 0.022 14.5 0.0 2.6 2 1 1 3 3 3 1 Sigma-54 interaction domain RuvB_N PF05496.12 EHT98932.1 - 0.0015 18.3 0.1 0.096 12.4 0.0 2.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EHT98932.1 - 0.0065 16.2 0.1 0.031 14.0 0.0 2.1 1 1 1 2 2 2 1 IstB-like ATP binding protein TniB PF05621.11 EHT98932.1 - 0.01 15.3 0.3 0.035 13.5 0.0 2.1 2 1 0 2 2 2 0 Bacterial TniB protein AAA_33 PF13671.6 EHT98932.1 - 0.01 16.0 0.0 0.025 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 EHT98932.1 - 0.015 14.5 0.5 0.059 12.6 0.0 1.9 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_28 PF13521.6 EHT98932.1 - 0.016 15.5 0.4 0.097 12.9 0.1 2.5 2 1 1 3 3 3 0 AAA domain AAA_14 PF13173.6 EHT98932.1 - 0.016 15.2 0.0 5.4 7.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EHT98932.1 - 0.03 14.0 0.2 0.11 12.2 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EHT98932.1 - 0.044 13.3 0.0 0.13 11.7 0.0 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 EHT98932.1 - 0.057 13.9 0.0 0.14 12.6 0.0 1.7 1 1 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 EHT98932.1 - 0.064 12.5 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin SRP54 PF00448.22 EHT98932.1 - 0.071 12.7 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DEAD PF00270.29 EHT98932.1 - 0.081 12.7 0.0 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase RsgA_GTPase PF03193.16 EHT98932.1 - 0.082 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase ATP-synt_ab PF00006.25 EHT98932.1 - 0.089 12.4 0.3 0.27 10.9 0.1 1.8 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain TsaE PF02367.17 EHT98932.1 - 0.089 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EHT98932.1 - 0.097 13.1 0.0 0.88 10.0 0.0 2.3 2 0 0 2 2 2 0 RNA helicase Proteasome PF00227.26 EHT98933.1 - 9.3e-23 80.7 0.1 1.6e-22 79.9 0.1 1.4 1 1 0 1 1 1 1 Proteasome subunit PspC PF04024.12 EHT98933.1 - 0.091 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 PspC domain SPOR PF05036.13 EHT98934.1 - 7.4e-18 64.7 2.3 8.8e-18 64.5 0.0 2.2 2 1 0 2 2 2 1 Sporulation related domain TFIIA PF03153.13 EHT98934.1 - 0.035 14.1 45.2 0.045 13.8 45.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit V_ATPase_I PF01496.19 EHT98934.1 - 0.47 8.3 17.6 0.56 8.1 17.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.15 EHT98934.1 - 2.3 7.7 23.2 3 7.3 23.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit ECM1 PF05782.11 EHT98934.1 - 3.6 6.4 24.0 5.3 5.9 24.0 1.3 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) PAT1 PF09770.9 EHT98934.1 - 3.9 5.6 40.8 5 5.3 40.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4366 PF14283.6 EHT98934.1 - 4.5 7.3 0.0 4.5 7.3 0.0 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) TRIQK PF15168.6 EHT98934.1 - 7.2 6.6 0.0 7.2 6.6 0.0 3.8 2 1 2 4 4 4 0 Triple QxxK/R motif-containing protein family Peripla_BP_3 PF13377.6 EHT98935.1 - 9.8e-43 146.4 0.0 2.6e-42 145.0 0.0 1.7 2 1 1 3 3 3 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 EHT98935.1 - 2e-29 102.9 0.0 3.1e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 EHT98935.1 - 1.2e-18 66.6 2.9 2.6e-18 65.5 2.9 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 EHT98935.1 - 5.5e-09 36.0 0.0 5.1e-07 29.5 0.0 2.7 3 0 0 3 3 3 1 Periplasmic binding protein domain TetR_N PF00440.23 EHT98935.1 - 0.0031 17.3 0.1 0.0066 16.2 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_Tnp_ISL3 PF13542.6 EHT98935.1 - 0.016 14.6 0.1 0.033 13.6 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_24 PF13412.6 EHT98935.1 - 0.045 13.3 0.0 0.16 11.5 0.0 2.0 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_10 PF04967.12 EHT98935.1 - 0.048 13.5 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 HTH DNA binding domain HTH_AsnC-type PF13404.6 EHT98935.1 - 0.066 13.1 0.1 0.31 10.9 0.1 2.1 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_3 PF01381.22 EHT98935.1 - 0.089 12.9 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix MarR_2 PF12802.7 EHT98935.1 - 0.15 12.0 0.5 0.55 10.1 0.0 2.2 2 0 0 2 2 2 0 MarR family PriA_3primeBD PF17764.1 EHT98936.1 - 5.8e-30 103.0 0.0 1.1e-29 102.2 0.0 1.5 1 0 0 1 1 1 1 3′ DNA-binding domain (3′BD) PriA_C PF18074.1 EHT98936.1 - 4.1e-20 72.4 0.1 4.2e-19 69.1 0.0 2.7 3 0 0 3 3 3 1 Primosomal protein N C-terminal domain DEAD PF00270.29 EHT98936.1 - 8.1e-12 45.3 0.0 1.6e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EHT98936.1 - 1.3e-11 44.8 0.0 2.2e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EHT98936.1 - 8.5e-11 42.2 0.0 5.2e-05 23.6 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain PriA_CRR PF18319.1 EHT98936.1 - 3.3e-07 30.2 17.0 3.3e-07 30.2 17.0 3.0 3 0 0 3 3 3 1 PriA DNA helicase Cys-rich region (CRR) domain TrwB_AAD_bind PF10412.9 EHT98936.1 - 0.0069 15.3 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 EHT98936.1 - 0.019 14.7 0.0 0.059 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EHT98936.1 - 0.051 13.8 0.0 0.96 9.7 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EHT98936.1 - 0.068 13.5 0.0 0.23 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain zinc-ribbons_6 PF07191.12 EHT98936.1 - 0.093 12.7 7.9 0.2 11.7 7.9 1.5 1 0 0 1 1 1 0 zinc-ribbons Ribosomal_L31 PF01197.18 EHT98937.1 - 8.9e-31 105.9 0.3 9.9e-31 105.8 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L31 MetJ PF01340.20 EHT98938.1 - 7.8e-59 195.7 0.1 8.7e-59 195.5 0.1 1.0 1 0 0 1 1 1 1 Met Apo-repressor, MetJ SWI2_SNF2 PF18766.1 EHT98938.1 - 0.083 12.5 0.0 0.087 12.5 0.0 1.1 1 0 0 1 1 1 0 SWI2/SNF2 ATPase AphA_like PF14557.6 EHT98938.1 - 0.17 11.6 0.0 0.2 11.4 0.0 1.1 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator Cys_Met_Meta_PP PF01053.20 EHT98939.1 - 4.2e-142 473.2 0.0 4.7e-142 473.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EHT98939.1 - 2.1e-07 30.5 0.0 3e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EHT98939.1 - 0.00043 19.3 0.0 0.00066 18.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V AA_kinase PF00696.28 EHT98940.1 - 3e-43 148.2 0.0 4.4e-43 147.6 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family Homoserine_dh PF00742.19 EHT98940.1 - 1.5e-42 145.5 0.0 2.4e-42 144.8 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 EHT98940.1 - 3.1e-25 89.1 0.0 9.5e-25 87.5 0.0 1.9 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DDE_Tnp_IS66 PF03050.14 EHT98941.1 - 9.3e-98 327.2 4.5 3.2e-97 325.4 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT98941.1 - 3.1e-16 59.3 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT98941.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT98941.1 - 8.9e-11 42.4 9.0 1.9e-10 41.4 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Phage_HK97_TLTM PF06120.11 EHT98941.1 - 0.011 15.0 0.8 0.021 14.0 0.8 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHT98941.1 - 0.02 15.2 4.2 0.084 13.2 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain UME PF08064.13 EHT98941.1 - 0.033 14.1 0.3 20 5.1 0.0 3.1 2 1 1 3 3 3 0 UME (NUC010) domain Exonuc_VII_L PF02601.15 EHT98941.1 - 0.039 13.5 2.7 0.04 13.5 1.0 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Troponin PF00992.20 EHT98941.1 - 0.044 14.1 2.8 0.078 13.3 2.8 1.3 1 0 0 1 1 1 0 Troponin FUSC PF04632.12 EHT98941.1 - 0.048 12.2 7.4 0.077 11.5 7.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tho2 PF11262.8 EHT98941.1 - 0.049 12.8 0.6 0.081 12.1 0.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FAM184 PF15665.5 EHT98941.1 - 0.052 13.3 8.0 0.082 12.7 8.0 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B HalX PF08663.10 EHT98941.1 - 0.13 12.6 2.4 0.34 11.3 2.4 1.7 1 0 0 1 1 1 0 HalX domain LXG PF04740.12 EHT98941.1 - 0.14 11.8 2.8 0.35 10.5 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHT98941.1 - 0.19 11.5 11.1 0.31 10.8 11.1 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DHR10 PF18595.1 EHT98941.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Zn-ribbon_8 PF09723.10 EHT98941.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF1192 PF06698.11 EHT98941.1 - 0.53 10.4 5.3 3.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHT98941.1 - 0.82 8.9 3.0 1.2 8.3 3.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHT98941.1 - 2 8.0 8.1 4.3 6.8 8.1 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHT98941.1 - 4.2 7.7 8.6 8.7 6.7 8.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CREPT PF16566.5 EHT98941.1 - 5.9 7.1 8.7 2.7 8.1 5.6 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour SlyX PF04102.12 EHT98941.1 - 9.3 7.0 9.0 18 6.1 2.3 3.0 1 1 1 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHT98942.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHT98943.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT98943.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT98943.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT98943.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix PEPcase PF00311.17 EHT98944.1 - 1e-81 275.2 0.1 1.1e-81 275.1 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase Asp_Glu_race PF01177.22 EHT98945.1 - 1.5e-25 90.4 0.0 1.9e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase TonB_dep_Rec PF00593.24 EHT98946.1 - 2.6e-46 159.5 44.7 4.1e-46 158.8 44.7 1.3 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 EHT98946.1 - 1.7e-27 96.1 0.4 5.2e-27 94.5 0.4 1.9 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain tRNA_U5-meth_tr PF05958.11 EHT98947.1 - 3.1e-189 628.4 0.9 3.5e-189 628.2 0.9 1.0 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_25 PF13649.6 EHT98947.1 - 7.8e-06 26.5 0.0 5.1e-05 23.9 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.10 EHT98947.1 - 0.00031 20.4 0.0 0.00051 19.7 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.17 EHT98947.1 - 0.00037 20.0 0.1 0.00067 19.2 0.1 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 EHT98947.1 - 0.00043 19.9 0.0 0.0013 18.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_11 PF08241.12 EHT98947.1 - 0.0011 19.6 0.0 0.0031 18.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EHT98947.1 - 0.0052 16.2 0.1 0.0094 15.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EHT98947.1 - 0.0052 16.6 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EHT98947.1 - 0.0056 16.4 0.0 0.0092 15.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein DUF3164 PF11363.8 EHT98947.1 - 0.049 13.2 0.7 0.085 12.5 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3164) DUF1422 PF07226.11 EHT98948.1 - 2.9e-49 165.8 0.5 3.3e-49 165.6 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1422) Bax1-I PF01027.20 EHT98948.1 - 0.011 15.6 3.9 0.013 15.3 3.9 1.0 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 AA_permease_2 PF13520.6 EHT98948.1 - 0.036 12.9 6.7 0.042 12.7 6.7 1.0 1 0 0 1 1 1 0 Amino acid permease CcmD PF04995.14 EHT98948.1 - 0.49 10.5 5.3 0.78 9.9 0.1 2.8 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) TetR_N PF00440.23 EHT98949.1 - 9.6e-09 34.9 0.7 2.5e-08 33.6 0.1 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_Tnp_1 PF01527.20 EHT98949.1 - 0.0039 17.5 0.3 1.5 9.2 0.0 3.1 3 0 0 3 3 3 2 Transposase YlaC PF10777.9 EHT98949.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.5 2 0 0 2 2 2 0 Inner membrane protein YlaC Pyr_redox_2 PF07992.14 EHT98950.1 - 1.2e-56 192.1 0.0 1.6e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EHT98950.1 - 1.3e-30 105.9 0.3 7e-30 103.5 0.6 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EHT98950.1 - 3.8e-18 65.8 2.7 2.4e-16 60.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EHT98950.1 - 1.4e-07 31.1 0.3 2.8e-06 26.8 0.3 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EHT98950.1 - 6.2e-07 29.1 0.0 1e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EHT98950.1 - 2.8e-06 27.5 1.1 0.00015 21.9 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EHT98950.1 - 1.2e-05 24.7 1.1 2.2e-05 23.8 0.4 1.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 EHT98950.1 - 5.5e-05 22.4 1.5 0.00014 21.1 1.5 1.6 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EHT98950.1 - 9.2e-05 21.7 0.3 0.08 12.0 0.1 3.3 4 0 0 4 4 4 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EHT98950.1 - 9.7e-05 21.8 1.1 0.00091 18.6 0.3 2.6 3 0 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.21 EHT98950.1 - 0.00027 20.3 0.1 0.0052 16.1 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 EHT98950.1 - 0.00029 19.6 1.4 0.031 13.0 1.2 2.7 2 0 0 2 2 2 1 HI0933-like protein K_oxygenase PF13434.6 EHT98950.1 - 0.0008 18.7 0.1 0.0025 17.0 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EHT98950.1 - 0.0047 16.9 0.3 1.8 8.5 0.2 2.8 2 1 1 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 EHT98950.1 - 0.0081 15.8 0.1 0.0081 15.8 0.1 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 EHT98950.1 - 0.015 15.2 1.2 2 8.2 0.0 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAPDH_C PF16654.5 EHT98950.1 - 0.084 12.7 0.1 0.47 10.3 0.0 2.2 2 1 0 2 2 2 0 Diaminopimelic acid dehydrogenase C-terminal domain Amino_oxidase PF01593.24 EHT98950.1 - 0.16 11.2 0.1 7.5 5.7 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase LysR_substrate PF03466.20 EHT98951.1 - 5.2e-52 176.2 0.8 7.6e-52 175.7 0.8 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EHT98951.1 - 9.5e-21 73.5 0.4 2.7e-20 72.1 0.2 1.9 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 EHT98951.1 - 0.0031 17.3 0.1 0.0095 15.7 0.1 1.8 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain Lyase_1 PF00206.20 EHT98952.1 - 2e-97 326.4 0.0 2.9e-97 325.9 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 EHT98952.1 - 1.7e-22 80.0 0.2 5.7e-22 78.2 0.2 2.0 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Sigma_1s PF02454.16 EHT98952.1 - 0.043 13.8 0.1 0.14 12.2 0.1 1.8 1 0 0 1 1 1 0 Sigma 1s protein K-box PF01486.17 EHT98952.1 - 2.7 8.2 6.3 0.77 10.0 0.7 2.7 3 1 1 4 4 4 0 K-box region Arginosuc_synth PF00764.19 EHT98953.1 - 3.2e-142 474.4 0.0 3.6e-142 474.2 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 EHT98953.1 - 0.038 13.5 0.0 0.074 12.5 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC AA_kinase PF00696.28 EHT98954.1 - 1.1e-39 136.5 2.8 1.2e-39 136.3 2.8 1.0 1 0 0 1 1 1 1 Amino acid kinase family Smr PF01713.21 EHT98954.1 - 0.062 13.7 0.0 0.27 11.6 0.0 2.0 2 0 0 2 2 2 0 Smr domain DUF4332 PF14229.6 EHT98954.1 - 0.076 13.3 0.3 0.23 11.7 0.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4332) GDE_N_bis PF14742.6 EHT98954.1 - 0.2 11.2 0.0 0.26 10.8 0.0 1.1 1 0 0 1 1 1 0 N-terminal domain of (some) glycogen debranching enzymes Semialdhyde_dh PF01118.24 EHT98955.1 - 2.4e-34 118.4 0.0 3.8e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 EHT98955.1 - 5.6e-16 59.2 0.0 8.7e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain GFO_IDH_MocA PF01408.22 EHT98955.1 - 0.02 15.7 0.0 0.068 14.0 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 EHT98955.1 - 0.081 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 EHT98955.1 - 0.15 11.5 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Peptidase_M20 PF01546.28 EHT98956.1 - 1.2e-31 110.0 0.0 2.3e-31 109.1 0.0 1.4 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EHT98956.1 - 2.4e-26 91.8 0.0 3.9e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EHT98956.1 - 0.0079 15.9 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.14 EHT98956.1 - 0.16 11.0 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase PEPcase PF00311.17 EHT98957.1 - 2e-291 968.8 0.0 2.6e-291 968.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.6 EHT98957.1 - 4.7e-05 22.1 0.0 8e-05 21.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase DUF4446 PF14584.6 EHT98957.1 - 0.14 12.1 0.1 0.38 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) HTH_Tnp_1 PF01527.20 EHT98958.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT98958.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT98958.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT98958.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHT98959.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHT98960.1 - 9.9e-75 251.6 6.6 1.2e-74 251.4 0.2 2.1 2 0 0 2 2 2 1 Transposase IS66 family zf-IS66 PF13005.7 EHT98960.1 - 1.1e-14 54.6 1.5 2.6e-14 53.3 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT98960.1 - 6.1e-11 42.9 9.0 1.4e-10 41.8 9.0 1.7 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Phage_HK97_TLTM PF06120.11 EHT98960.1 - 0.0088 15.3 1.0 0.018 14.3 1.0 1.4 1 0 0 1 1 1 1 Tail length tape measure protein Csm1_N PF18504.1 EHT98960.1 - 0.014 15.7 4.4 0.064 13.6 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain UME PF08064.13 EHT98960.1 - 0.018 15.0 0.3 16 5.5 0.0 3.1 2 1 0 3 3 3 0 UME (NUC010) domain Troponin PF00992.20 EHT98960.1 - 0.031 14.6 2.8 0.056 13.7 2.8 1.4 1 0 0 1 1 1 0 Troponin Tho2 PF11262.8 EHT98960.1 - 0.034 13.3 0.4 0.055 12.7 0.4 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Exonuc_VII_L PF02601.15 EHT98960.1 - 0.035 13.7 2.8 0.027 14.0 1.0 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit FAM184 PF15665.5 EHT98960.1 - 0.037 13.8 8.0 0.059 13.1 8.0 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B FUSC PF04632.12 EHT98960.1 - 0.038 12.5 7.5 0.057 12.0 7.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family LXG PF04740.12 EHT98960.1 - 0.088 12.5 2.8 0.25 11.0 0.4 2.2 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHT98960.1 - 0.11 12.3 10.8 0.18 11.6 10.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Zn-ribbon_8 PF09723.10 EHT98960.1 - 0.23 11.6 1.7 0.8 9.9 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain DHR10 PF18595.1 EHT98960.1 - 0.27 11.3 10.9 0.48 10.5 10.9 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF1192 PF06698.11 EHT98960.1 - 0.32 11.1 5.3 2.7 8.1 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHT98960.1 - 0.61 9.3 3.0 0.9 8.7 3.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHT98960.1 - 1.2 8.7 7.9 2.6 7.6 7.9 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 HalX PF08663.10 EHT98960.1 - 1.2 9.5 6.0 0.25 11.7 2.4 1.8 2 0 0 2 2 1 0 HalX domain OmpH PF03938.14 EHT98960.1 - 3.7 7.9 8.9 7.2 6.9 8.9 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 EHT98960.1 - 5.6 7.7 8.9 10 6.8 1.9 3.0 1 1 1 2 2 2 0 SlyX Fic PF02661.18 EHT98961.1 - 7e-17 62.1 0.0 1.2e-16 61.4 0.0 1.4 1 0 0 1 1 1 1 Fic/DOC family DUF2559 PF10832.8 EHT98962.1 - 3.9e-26 90.9 1.1 4.4e-26 90.7 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2559) Pro_isomerase PF00160.21 EHT98963.1 - 1.4e-48 165.2 0.7 1.6e-48 165.0 0.7 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DDE_3 PF13358.6 EHT98964.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHT98964.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHT98964.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHT98964.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHT98964.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHT98964.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHT98964.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHT98964.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 MFS_1 PF07690.16 EHT98965.1 - 3.4e-25 88.7 53.3 2.1e-24 86.1 44.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2_3 PF16080.5 EHT98965.1 - 0.43 10.4 0.1 0.43 10.4 0.1 3.3 4 0 0 4 4 4 0 Bacteriophage holin family HP1 Amidohydro_3 PF07969.11 EHT98966.1 - 2.5e-53 182.2 0.2 3.7e-52 178.4 0.2 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 EHT98966.1 - 2.9e-13 49.9 0.0 3.9e-13 49.4 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family tRNA-synt_1b PF00579.25 EHT98967.1 - 2e-87 293.3 0.0 2.6e-87 292.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Apo-CIII PF05778.12 EHT98967.1 - 0.19 11.4 0.8 0.45 10.2 0.3 1.9 2 0 0 2 2 2 0 Apolipoprotein CIII (Apo-CIII) HAD_2 PF13419.6 EHT98968.1 - 2e-31 109.5 0.0 2.4e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EHT98968.1 - 1.1e-21 78.1 0.0 2.3e-21 77.0 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EHT98968.1 - 3.2e-12 47.3 0.0 4.2e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EHT98968.1 - 8.2e-08 32.2 0.0 2.1e-07 30.9 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_3 PF08282.12 EHT98968.1 - 4.9e-06 26.5 0.2 0.07 12.9 0.0 3.0 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EHT98968.1 - 1.2e-05 25.4 0.0 8.4e-05 22.6 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase S6PP PF05116.13 EHT98968.1 - 0.15 11.6 0.1 0.74 9.3 0.0 1.9 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Ribul_P_3_epim PF00834.19 EHT98969.1 - 6.1e-90 299.9 0.0 7.1e-90 299.7 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 EHT98969.1 - 7.3e-06 25.9 0.0 0.00029 20.7 0.0 2.2 2 1 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.21 EHT98969.1 - 0.028 13.9 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein FMN_dh PF01070.18 EHT98969.1 - 0.033 13.2 1.7 0.36 9.8 0.1 2.2 2 0 0 2 2 2 0 FMN-dependent dehydrogenase PGM_PMM_II PF02879.16 EHT98969.1 - 0.037 14.6 0.0 0.16 12.6 0.0 2.0 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II TMP-TENI PF02581.17 EHT98969.1 - 0.083 12.2 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 Thiamine monophosphate synthase Radical_SAM PF04055.21 EHT98969.1 - 0.099 13.0 0.0 3.9 7.8 0.0 2.4 1 1 1 2 2 2 0 Radical SAM superfamily MethyltransfD12 PF02086.15 EHT98970.1 - 2.7e-74 250.1 0.1 3.1e-74 250.0 0.1 1.0 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase SPOR PF05036.13 EHT98971.1 - 1.1e-10 41.7 0.3 2.1e-10 40.8 0.3 1.5 1 0 0 1 1 1 1 Sporulation related domain DHQ_synthase PF01761.20 EHT98972.1 - 1.7e-109 365.0 0.0 2.2e-109 364.7 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 EHT98972.1 - 8.7e-14 51.8 0.7 9.7e-13 48.4 0.7 2.1 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 EHT98972.1 - 3.7e-09 35.9 2.9 2e-08 33.4 0.2 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase SKI PF01202.22 EHT98973.1 - 1.3e-56 191.1 0.6 1.5e-56 190.9 0.6 1.0 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 EHT98973.1 - 3.6e-09 36.9 0.1 2.7e-06 27.6 0.0 2.1 1 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EHT98973.1 - 5.1e-07 30.3 0.0 8e-07 29.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 EHT98973.1 - 3.5e-06 26.9 0.6 4.7e-05 23.2 0.0 2.5 2 1 1 3 3 3 1 Cytidylate kinase dNK PF01712.19 EHT98973.1 - 1.8e-05 24.7 0.0 0.015 15.1 0.0 2.2 2 0 0 2 2 2 2 Deoxynucleoside kinase Cytidylate_kin2 PF13189.6 EHT98973.1 - 3.6e-05 24.0 0.1 0.00099 19.3 0.1 2.4 1 1 1 2 2 2 1 Cytidylate kinase-like family AAA PF00004.29 EHT98973.1 - 0.00048 20.6 0.0 0.0012 19.2 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EHT98973.1 - 0.00092 19.6 0.2 0.0024 18.3 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EHT98973.1 - 0.0015 18.8 0.0 0.0021 18.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 EHT98973.1 - 0.002 18.1 0.0 0.0045 17.0 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 EHT98973.1 - 0.0034 17.9 0.2 0.011 16.3 0.2 1.9 1 1 0 1 1 1 1 ABC transporter APS_kinase PF01583.20 EHT98973.1 - 0.0058 16.5 0.1 0.014 15.3 0.1 1.7 1 1 0 1 1 1 1 Adenylylsulphate kinase AAA_5 PF07728.14 EHT98973.1 - 0.0059 16.6 0.0 0.015 15.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EHT98973.1 - 0.0071 15.9 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region Ploopntkinase3 PF18751.1 EHT98973.1 - 0.011 15.7 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_25 PF13481.6 EHT98973.1 - 0.011 15.3 0.2 0.029 13.9 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EHT98973.1 - 0.012 16.1 2.3 0.11 12.9 0.5 2.9 1 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EHT98973.1 - 0.013 15.2 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EHT98973.1 - 0.017 15.4 0.0 0.14 12.4 0.0 2.2 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EHT98973.1 - 0.018 15.4 0.0 0.033 14.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_PrkA PF08298.11 EHT98973.1 - 0.024 13.6 0.0 0.047 12.6 0.0 1.5 1 0 0 1 1 1 0 PrkA AAA domain His_biosynth PF00977.21 EHT98973.1 - 0.033 13.6 0.1 0.033 13.6 0.1 1.2 1 0 0 1 1 1 0 Histidine biosynthesis protein AAA_29 PF13555.6 EHT98973.1 - 0.042 13.6 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EHT98973.1 - 0.051 13.5 0.0 0.11 12.3 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase Mg_chelatase PF01078.21 EHT98973.1 - 0.09 12.1 0.2 0.14 11.5 0.0 1.6 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EHT98973.1 - 0.094 12.8 0.0 0.39 10.8 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_2 PF07724.14 EHT98973.1 - 0.1 12.7 2.8 0.3 11.2 0.6 2.5 2 1 1 3 3 3 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EHT98973.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein HofP PF10748.9 EHT98974.1 - 1.6e-09 37.4 0.0 1.8e-09 37.3 0.0 1.0 1 0 0 1 1 1 1 DNA utilization proteins HofP PilN PF05137.13 EHT98975.1 - 8.2e-09 35.5 0.0 1.7e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Fimbrial assembly protein (PilN) DUF4094 PF13334.6 EHT98975.1 - 0.0031 17.9 0.6 0.0047 17.3 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4094) TMEM100 PF16311.5 EHT98975.1 - 0.046 13.3 3.8 0.06 12.9 3.1 1.6 1 1 1 2 2 2 0 Transmembrane protein 100 RskA PF10099.9 EHT98975.1 - 0.23 11.7 4.0 0.26 11.5 3.4 1.3 1 1 0 1 1 1 0 Anti-sigma-K factor rskA PilM_2 PF11104.8 EHT98976.1 - 2.7e-10 39.8 0.0 8.4e-09 34.9 0.0 2.0 2 0 0 2 2 2 2 Type IV pilus assembly protein PilM; Transgly PF00912.22 EHT98977.1 - 2.6e-63 212.7 0.0 5.8e-63 211.6 0.0 1.6 1 0 0 1 1 1 1 Transglycosylase PCB_OB PF17092.5 EHT98977.1 - 9.5e-31 106.9 1.7 2.6e-30 105.4 1.7 1.8 1 0 0 1 1 1 1 Penicillin-binding protein OB-like domain Transpeptidase PF00905.22 EHT98977.1 - 1.5e-25 90.0 0.0 9.2e-24 84.2 0.0 2.6 2 1 0 2 2 2 1 Penicillin binding protein transpeptidase domain NUDIX PF00293.28 EHT98978.1 - 5.4e-14 52.4 0.0 1.1e-13 51.4 0.0 1.5 2 0 0 2 2 2 1 NUDIX domain IgaA PF07095.11 EHT98979.1 - 0 1176.7 0.1 0 1176.5 0.1 1.0 1 0 0 1 1 1 1 Intracellular growth attenuator protein IgaA DUF1275 PF06912.11 EHT98979.1 - 0.095 12.6 1.6 5.9 6.8 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1275) S4 PF01479.25 EHT98980.1 - 9e-14 50.9 0.1 1.8e-13 49.9 0.0 1.6 2 0 0 2 2 2 1 S4 domain HSP33 PF01430.19 EHT98981.1 - 5.7e-86 288.2 0.0 6.4e-86 288.1 0.0 1.0 1 0 0 1 1 1 1 Hsp33 protein PEPCK_ATP PF01293.20 EHT98982.1 - 1.7e-210 699.6 0.0 2e-210 699.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 EHT98982.1 - 1.9e-05 24.8 0.1 0.34 11.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain HATPase_c PF02518.26 EHT98983.1 - 3.1e-21 76.0 0.0 5.6e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EHT98983.1 - 5.4e-10 39.2 0.1 1.3e-09 37.9 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 EHT98983.1 - 3.4e-08 33.7 0.1 4.3e-07 30.2 0.0 2.8 3 0 0 3 3 3 1 HAMP domain HATPase_c_3 PF13589.6 EHT98983.1 - 0.0026 17.6 0.0 0.0045 16.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EHT98983.1 - 0.0063 16.5 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Response_reg PF00072.24 EHT98984.1 - 9.6e-30 103.0 0.0 1.4e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 EHT98984.1 - 9.1e-23 80.1 0.0 2.2e-22 78.9 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal FleQ PF06490.11 EHT98984.1 - 0.006 17.0 0.0 0.012 16.0 0.0 1.5 2 0 0 2 2 2 1 Flagellar regulatory protein FleQ YjbE PF11106.8 EHT98985.1 - 4.2e-29 100.6 21.3 4.7e-29 100.4 21.3 1.0 1 0 0 1 1 1 1 Exopolysaccharide production protein YjbE TraT PF05818.12 EHT98985.1 - 0.97 9.1 8.3 1.1 8.9 8.3 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein UL73_N PF12522.8 EHT98985.1 - 6.2 6.7 18.3 0.62 9.9 9.4 2.5 2 0 0 2 2 2 0 Cytomegalovirus glycoprotein N terminal GreA_GreB_N PF03449.15 EHT98986.1 - 2.5e-25 88.4 0.8 3.4e-25 88.0 0.8 1.2 1 0 0 1 1 1 1 Transcription elongation factor, N-terminal GreA_GreB PF01272.19 EHT98986.1 - 2.6e-21 75.3 0.0 4.2e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term DUF1481 PF07356.12 EHT98986.1 - 0.079 12.7 0.3 0.11 12.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1481) Tex_N PF09371.10 EHT98987.1 - 1.8e-72 242.9 0.3 2.9e-72 242.2 0.3 1.4 1 0 0 1 1 1 1 Tex-like protein N-terminal domain Tex_YqgF PF16921.5 EHT98987.1 - 3.5e-50 169.7 0.3 6.2e-50 168.9 0.3 1.4 1 0 0 1 1 1 1 Tex protein YqgF-like domain HHH_3 PF12836.7 EHT98987.1 - 8e-28 96.5 0.0 2.3e-27 95.0 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif S1 PF00575.23 EHT98987.1 - 3.8e-23 81.6 0.8 7.1e-23 80.7 0.8 1.5 1 0 0 1 1 1 1 S1 RNA binding domain HHH_9 PF17674.1 EHT98987.1 - 6.3e-23 81.5 0.0 2.4e-22 79.6 0.0 2.1 1 0 0 1 1 1 1 HHH domain HHH_7 PF14635.6 EHT98987.1 - 1.1e-10 41.8 0.0 3.1e-10 40.3 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 EHT98987.1 - 9.4e-07 28.7 0.0 2.2e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 CRS1_YhbY PF01985.21 EHT98987.1 - 0.08 13.1 0.4 8.9 6.6 0.1 2.7 2 0 0 2 2 2 0 CRS1 / YhbY (CRM) domain HHH_6 PF14579.6 EHT98987.1 - 0.1 12.9 0.1 0.83 9.9 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif TPR_5 PF12688.7 EHT98987.1 - 0.53 10.5 5.4 0.28 11.4 0.9 2.6 2 1 0 2 2 2 0 Tetratrico peptide repeat Alpha-amylase PF00128.24 EHT98988.1 - 2.3e-18 66.9 0.0 9.7e-17 61.5 0.0 2.1 2 0 0 2 2 2 2 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 EHT98988.1 - 0.022 14.9 0.0 0.063 13.4 0.0 1.8 1 0 0 1 1 1 0 Maltogenic Amylase, C-terminal domain DUF1471 PF07338.13 EHT98989.1 - 8.1e-20 70.6 0.3 2.5e-19 69.0 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1471) Ground-like PF04155.18 EHT98989.1 - 0.048 14.3 0.0 0.062 14.0 0.0 1.4 1 1 0 1 1 1 0 Ground-like domain Abhydrolase_1 PF00561.20 EHT98990.1 - 2.4e-25 89.6 0.1 2.9e-25 89.4 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EHT98990.1 - 1.6e-17 64.8 6.1 1.9e-17 64.6 6.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EHT98990.1 - 3.3e-12 46.2 0.1 1.3e-11 44.3 0.1 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EHT98990.1 - 3.1e-08 34.0 0.0 5.1e-08 33.3 0.0 1.3 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_2 PF02230.16 EHT98990.1 - 5e-06 26.5 0.0 0.64 9.8 0.0 3.1 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.7 EHT98990.1 - 7.8e-05 22.5 0.0 0.39 10.5 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family FSH1 PF03959.13 EHT98990.1 - 0.0044 16.7 0.0 0.031 14.0 0.0 2.2 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Esterase PF00756.20 EHT98990.1 - 0.12 12.1 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase UPF0227 PF05728.12 EHT98990.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) Pribosyltran PF00156.27 EHT98991.1 - 1.9e-10 40.5 0.0 3.1e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EHT98991.1 - 0.011 15.2 0.0 0.023 14.1 0.0 1.5 2 0 0 2 2 2 0 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 EHT98991.1 - 0.017 14.6 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase PRTase_3 PF15610.6 EHT98991.1 - 0.039 13.2 0.0 0.051 12.8 0.0 1.1 1 0 0 1 1 1 0 PRTase ComF-like Pribosyl_synth PF14572.6 EHT98991.1 - 0.15 12.1 0.0 0.2 11.7 0.0 1.1 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain DUF1612 PF07756.12 EHT98991.1 - 1.2 9.4 5.9 0.087 13.1 0.7 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1612) DZR PF12773.7 EHT98991.1 - 4 7.5 8.3 8.8 6.5 7.3 2.0 1 1 1 2 2 2 0 Double zinc ribbon NifU PF01106.17 EHT98992.1 - 3.5e-19 68.7 0.0 6.6e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 NifU-like domain Fe-S_biosyn PF01521.20 EHT98992.1 - 1e-13 51.4 0.1 2.4e-13 50.3 0.0 1.6 2 0 0 2 2 2 1 Iron-sulphur cluster biosynthesis Phosphorylase PF00343.20 EHT98993.1 - 1.4e-295 982.2 0.0 1.6e-295 982.0 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase DeoRC PF00455.22 EHT98994.1 - 4.8e-54 182.6 0.0 6.9e-54 182.1 0.0 1.2 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 EHT98994.1 - 1.3e-23 82.5 0.1 2.5e-23 81.6 0.1 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 EHT98994.1 - 2.9e-06 27.1 0.0 5.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 HTH domain GntR PF00392.21 EHT98994.1 - 2.6e-05 23.8 0.0 5.5e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family AcetylCoA_hydro PF02550.15 EHT98994.1 - 0.0023 17.9 0.0 0.011 15.7 0.0 1.8 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase N-terminal domain CoA_trans PF01144.23 EHT98994.1 - 0.0024 17.3 0.0 0.0032 16.9 0.0 1.2 1 0 0 1 1 1 1 Coenzyme A transferase DUF977 PF06163.11 EHT98994.1 - 0.021 14.8 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) Methyltransf_28 PF02636.17 EHT98994.1 - 0.028 14.0 0.0 0.063 12.9 0.0 1.6 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Put_DNA-bind_N PF06971.13 EHT98994.1 - 0.036 14.1 0.0 0.064 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus TFIIE_alpha PF02002.17 EHT98994.1 - 0.046 13.6 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 TFIIE alpha subunit HTH_Crp_2 PF13545.6 EHT98994.1 - 0.063 13.3 0.1 0.26 11.3 0.0 2.0 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain DDRGK PF09756.9 EHT98994.1 - 0.1 12.2 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 DDRGK domain HTH_Tnp_Tc3_2 PF01498.18 EHT98994.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Transposase Rhomboid PF01694.22 EHT98995.1 - 7.1e-28 97.5 15.1 7.1e-28 97.5 15.1 1.6 2 0 0 2 2 2 1 Rhomboid family Rhomboid_N PF12122.8 EHT98995.1 - 7.5e-27 93.3 0.2 1e-26 92.9 0.2 1.2 1 0 0 1 1 1 1 Cytoplasmic N-terminal domain of rhomboid serine protease Rhodanese PF00581.20 EHT98996.1 - 1.6e-11 44.7 0.0 2.2e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain DAO PF01266.24 EHT98997.1 - 2.6e-47 162.1 0.5 6.6e-47 160.8 0.0 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase DAO_C PF16901.5 EHT98997.1 - 3.8e-14 52.7 0.0 8.3e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 EHT98997.1 - 0.002 17.3 3.5 0.53 9.3 3.9 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EHT98997.1 - 0.0067 16.6 0.8 0.027 14.7 0.8 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EHT98997.1 - 0.011 15.0 0.2 0.04 13.1 0.2 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EHT98997.1 - 0.02 14.8 0.1 0.032 14.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 EHT98997.1 - 0.24 10.4 1.5 0.4 9.7 1.5 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 EHT98997.1 - 0.39 9.8 2.2 0.55 9.2 2.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 EHT98997.1 - 0.48 9.7 5.1 0.33 10.3 3.1 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase NTP_transferase PF00483.23 EHT98998.1 - 6e-67 225.8 0.0 7.3e-67 225.5 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EHT98998.1 - 3.8e-08 33.8 0.0 6.5e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 EHT98998.1 - 0.0094 14.9 0.1 0.87 8.5 0.1 2.2 2 0 0 2 2 2 2 L-fucokinase Hexapep PF00132.24 EHT98998.1 - 0.39 10.5 0.1 0.39 10.5 0.1 2.6 2 1 1 3 3 3 0 Bacterial transferase hexapeptide (six repeats) GlgX_C PF18390.1 EHT98999.1 - 8.2e-40 134.5 0.6 2e-39 133.3 0.6 1.7 1 0 0 1 1 1 1 Glycogen debranching enzyme C-terminal domain CBM_48 PF02922.18 EHT98999.1 - 8.4e-20 70.9 0.0 2.1e-19 69.6 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 EHT98999.1 - 2.6e-17 63.4 0.0 3.1e-08 33.6 0.0 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Semialdhyde_dhC PF02774.18 EHT99000.1 - 1.2e-59 201.5 0.0 1.5e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 EHT99000.1 - 5.1e-26 91.5 0.0 1e-25 90.5 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain MarC PF01914.17 EHT99001.1 - 1.5e-59 200.8 18.2 1.7e-59 200.6 18.2 1.0 1 0 0 1 1 1 1 MarC family integral membrane protein TerC PF03741.16 EHT99001.1 - 3.6e-06 26.8 0.6 3.6e-06 26.8 0.6 2.2 2 0 0 2 2 2 1 Integral membrane protein TerC family ST7 PF04184.12 EHT99001.1 - 0.11 11.0 0.1 0.16 10.4 0.1 1.2 1 0 0 1 1 1 0 ST7 protein DUF1980 PF09323.10 EHT99001.1 - 1.7 8.5 3.8 3.3 7.6 3.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1980) Mntp PF02659.15 EHT99001.1 - 1.9 8.2 13.7 1.1 9.0 3.6 2.3 2 0 0 2 2 2 0 Putative manganese efflux pump DUF202 PF02656.15 EHT99001.1 - 5.7 7.5 13.2 0.33 11.4 2.2 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF202) SKI PF01202.22 EHT99002.1 - 1.3e-11 44.9 0.0 1.5e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 EHT99002.1 - 4.3e-08 33.4 0.0 6.5e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EHT99002.1 - 2.1e-07 31.6 0.0 2.8e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 EHT99002.1 - 2.4e-06 27.5 0.0 3e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.6 EHT99002.1 - 0.00036 21.0 0.0 0.00048 20.5 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EHT99002.1 - 0.0032 17.7 0.0 0.0063 16.8 0.0 1.7 2 1 0 2 2 2 1 AAA domain dNK PF01712.19 EHT99002.1 - 0.0067 16.3 0.0 0.27 11.1 0.0 2.1 2 0 0 2 2 2 1 Deoxynucleoside kinase Cytidylate_kin PF02224.18 EHT99002.1 - 0.0094 15.7 0.2 0.021 14.6 0.0 1.6 2 1 0 2 2 2 1 Cytidylate kinase DUF2075 PF09848.9 EHT99002.1 - 0.01 15.1 0.0 0.01 15.1 0.0 1.2 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 EHT99002.1 - 0.023 14.2 0.1 0.23 10.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 EHT99002.1 - 0.027 13.8 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EHT99002.1 - 0.032 14.2 0.0 0.097 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 EHT99002.1 - 0.039 14.4 0.0 0.08 13.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EHT99002.1 - 0.086 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Ploopntkinase1 PF18748.1 EHT99002.1 - 0.096 12.2 0.0 1.9 8.0 0.0 2.0 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 Peripla_BP_1 PF00532.21 EHT99003.1 - 1.1e-29 103.8 0.0 1.4e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 EHT99003.1 - 9.7e-26 91.1 0.2 1.1e-24 87.6 0.2 2.2 2 0 0 2 2 2 1 Periplasmic binding protein-like domain LacI PF00356.21 EHT99003.1 - 2.9e-15 55.8 0.0 9.9e-15 54.1 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 EHT99003.1 - 1.6e-09 37.7 0.0 2.4e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein domain HTH_3 PF01381.22 EHT99003.1 - 0.00045 20.2 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_10 PF04967.12 EHT99003.1 - 0.002 17.9 0.0 0.006 16.4 0.0 1.8 1 0 0 1 1 1 1 HTH DNA binding domain HTH_24 PF13412.6 EHT99003.1 - 0.045 13.3 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 EHT99003.1 - 0.049 13.4 0.1 0.17 11.7 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_26 PF13443.6 EHT99003.1 - 0.1 13.1 0.0 0.27 11.7 0.0 1.8 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain HTH_CodY PF08222.11 EHT99003.1 - 0.17 11.5 0.0 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 CodY helix-turn-helix domain Pirin PF02678.16 EHT99004.1 - 7.7e-37 125.6 0.5 1.3e-36 124.9 0.5 1.3 1 0 0 1 1 1 1 Pirin Pirin_C_2 PF17954.1 EHT99004.1 - 1.4e-24 86.1 0.1 4.8e-24 84.3 0.1 1.8 2 0 0 2 2 2 1 Quercetinase C-terminal cupin domain Cupin_2 PF07883.11 EHT99004.1 - 4.1e-09 36.0 0.2 2.6e-08 33.5 0.2 2.1 2 0 0 2 2 2 1 Cupin domain Pirin_C PF05726.13 EHT99004.1 - 0.0017 18.7 0.0 0.64 10.4 0.0 2.2 2 0 0 2 2 2 2 Pirin C-terminal cupin domain 2OG-FeII_Oxy PF03171.20 EHT99004.1 - 0.085 13.4 0.0 0.23 12.0 0.0 1.8 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Acetyltransf_1 PF00583.25 EHT99005.1 - 7.1e-17 61.7 0.0 8.8e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EHT99005.1 - 3.2e-12 46.5 0.0 4.2e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EHT99005.1 - 2.2e-11 44.0 0.0 3.1e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EHT99005.1 - 4.1e-10 40.5 0.0 5.4e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EHT99005.1 - 4.2e-09 36.7 0.0 5.1e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EHT99005.1 - 5.5e-06 26.1 0.1 1.9e-05 24.4 0.1 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 EHT99005.1 - 1.8e-05 24.9 0.1 2.3e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EHT99005.1 - 0.00015 21.7 0.0 0.00024 21.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EHT99005.1 - 0.057 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF2756 PF10956.8 EHT99006.1 - 1.5e-18 67.2 30.5 1.6e-18 67.1 30.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2756) MSP1a PF11670.8 EHT99006.1 - 0.064 12.5 0.8 0.17 11.2 0.0 1.8 1 1 1 2 2 2 0 Major surface protein 1a (MSP1a) MCD PF05292.11 EHT99006.1 - 0.082 12.5 2.3 0.089 12.3 2.3 1.0 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase C-terminal domain U1snRNP70_N PF12220.8 EHT99006.1 - 0.14 12.8 6.4 0.21 12.2 6.4 1.4 1 1 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF1980 PF09323.10 EHT99006.1 - 0.22 11.4 3.7 0.24 11.3 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) CSG2 PF16965.5 EHT99006.1 - 0.3 10.0 2.7 0.35 9.8 2.7 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator Presenilin PF01080.17 EHT99006.1 - 0.6 8.8 7.7 0.62 8.8 7.7 1.1 1 0 0 1 1 1 0 Presenilin LMBR1 PF04791.16 EHT99006.1 - 1.8 7.4 5.0 1.8 7.4 5.0 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein FliP PF00813.20 EHT99006.1 - 1.9 8.3 4.0 2 8.2 4.0 1.2 1 0 0 1 1 1 0 FliP family DUF4407 PF14362.6 EHT99006.1 - 2 7.7 9.4 2.1 7.6 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PepSY_TM PF03929.16 EHT99006.1 - 2.4 7.7 4.2 4.7 6.8 4.2 1.5 1 1 0 1 1 1 0 PepSY-associated TM region GDPD PF03009.17 EHT99007.1 - 6.8e-38 130.9 0.0 8.2e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 EHT99007.1 - 4.8e-05 23.7 0.0 0.00012 22.4 0.0 1.7 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family ABC_tran PF00005.27 EHT99008.1 - 3.4e-31 108.6 0.0 5.2e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter OB_MalK PF17912.1 EHT99008.1 - 4e-11 43.6 0.0 1.5e-10 41.7 0.0 2.1 1 0 0 1 1 1 1 MalK OB fold domain TOBE_2 PF08402.10 EHT99008.1 - 3.9e-10 39.7 0.1 1.2e-09 38.2 0.1 1.9 1 0 0 1 1 1 1 TOBE domain AAA_21 PF13304.6 EHT99008.1 - 7.9e-07 29.2 0.0 0.013 15.3 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EHT99008.1 - 1.9e-05 25.1 0.0 3.9e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EHT99008.1 - 7.7e-05 22.7 0.0 0.00015 21.8 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 EHT99008.1 - 0.00056 19.4 0.1 0.0043 16.5 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain CysA_C_terminal PF17850.1 EHT99008.1 - 0.001 19.6 0.4 0.0055 17.2 0.1 2.4 2 0 0 2 2 2 1 CysA C-terminal regulatory domain AAA_33 PF13671.6 EHT99008.1 - 0.001 19.2 0.1 0.0022 18.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EHT99008.1 - 0.0045 17.3 0.2 0.0098 16.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EHT99008.1 - 0.0072 16.0 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATPase_2 PF01637.18 EHT99008.1 - 0.012 15.5 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 EHT99008.1 - 0.022 14.1 0.0 0.041 13.3 0.0 1.5 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 EHT99008.1 - 0.028 14.9 0.1 0.057 13.9 0.1 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EHT99008.1 - 0.028 14.3 0.0 0.043 13.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain PhoH PF02562.16 EHT99008.1 - 0.047 13.2 0.1 0.54 9.7 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein NB-ARC PF00931.22 EHT99008.1 - 0.047 12.9 0.1 0.083 12.1 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 EHT99008.1 - 0.078 12.9 0.7 0.25 11.2 0.0 2.1 2 1 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 EHT99008.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EHT99008.1 - 0.11 12.0 0.1 0.37 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EHT99008.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EHT99008.1 - 0.14 12.7 0.0 0.22 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EHT99008.1 - 0.14 12.1 0.8 0.39 10.7 0.0 2.1 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) BPD_transp_1 PF00528.22 EHT99009.1 - 1.5e-20 73.7 20.3 1.5e-20 73.7 20.3 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 EHT99010.1 - 1e-16 61.2 22.2 1e-16 61.2 22.2 1.8 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component SBP_bac_8 PF13416.6 EHT99011.1 - 1.9e-42 146.0 11.4 2.4e-42 145.7 11.4 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 EHT99011.1 - 2.4e-36 126.3 10.2 3.8e-36 125.7 10.2 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 EHT99011.1 - 1.9e-05 24.2 0.2 0.062 12.7 0.0 2.3 2 0 0 2 2 2 2 Bacterial extracellular solute-binding protein ABC_tran PF00005.27 EHT99012.1 - 8.8e-34 117.0 0.0 1.2e-33 116.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EHT99012.1 - 1.6e-10 41.3 0.1 0.00019 21.3 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EHT99012.1 - 0.00075 19.2 0.1 0.0018 18.0 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EHT99012.1 - 0.003 18.0 0.1 0.0062 16.9 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EHT99012.1 - 0.0041 17.0 0.1 0.0086 16.0 0.0 1.5 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 EHT99012.1 - 0.0097 16.4 0.1 0.015 15.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EHT99012.1 - 0.015 15.4 0.1 0.038 14.1 0.1 1.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase SMC_N PF02463.19 EHT99012.1 - 0.018 14.5 0.1 2.5 7.5 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EHT99012.1 - 0.02 14.6 0.1 0.034 13.9 0.1 1.3 1 0 0 1 1 1 0 AAA ATPase domain BCA_ABC_TP_C PF12399.8 EHT99012.1 - 0.028 14.4 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter AAA_33 PF13671.6 EHT99012.1 - 0.029 14.5 0.4 0.098 12.8 0.4 2.1 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EHT99012.1 - 0.031 13.9 0.1 0.064 12.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EHT99012.1 - 0.041 13.9 0.1 0.56 10.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_13 PF13166.6 EHT99012.1 - 0.045 12.4 0.0 0.064 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EHT99012.1 - 0.093 13.0 0.1 0.46 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EHT99012.1 - 0.12 12.6 0.3 1.3 9.3 0.3 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit cobW PF02492.19 EHT99012.1 - 0.12 12.0 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 EHT99012.1 - 0.14 11.8 0.5 0.21 11.3 0.5 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EHT99012.1 - 0.17 11.8 0.5 0.32 10.9 0.1 1.6 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 EHT99012.1 - 0.17 11.9 0.1 0.32 11.0 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EHT99012.1 - 0.18 12.1 0.5 0.38 11.0 0.5 1.6 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 EHT99012.1 - 0.2 11.9 0.0 0.36 11.1 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF3584 PF12128.8 EHT99012.1 - 0.34 8.4 0.4 0.43 8.0 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ABC_tran PF00005.27 EHT99013.1 - 1.8e-33 115.9 0.0 2.4e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 ABC transporter BCA_ABC_TP_C PF12399.8 EHT99013.1 - 3.7e-11 42.7 0.9 5.5e-11 42.1 0.1 1.8 2 0 0 2 2 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_21 PF13304.6 EHT99013.1 - 2.8e-06 27.4 0.1 0.00098 19.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EHT99013.1 - 0.00012 22.7 0.1 0.00017 22.2 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EHT99013.1 - 0.0016 18.2 0.1 0.02 14.6 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 EHT99013.1 - 0.0034 16.9 0.0 0.15 11.5 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EHT99013.1 - 0.0047 16.6 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EHT99013.1 - 0.0049 17.3 0.1 0.01 16.2 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EHT99013.1 - 0.015 15.6 0.1 0.17 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EHT99013.1 - 0.039 13.8 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase FeoB_N PF02421.18 EHT99013.1 - 0.06 12.9 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_30 PF13604.6 EHT99013.1 - 0.068 12.9 0.1 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 EHT99013.1 - 0.094 12.3 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Rad17 PF03215.15 EHT99013.1 - 0.18 11.7 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 EHT99013.1 - 0.19 11.8 0.3 0.45 10.6 0.2 1.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase SRPRB PF09439.10 EHT99013.1 - 0.23 10.9 0.0 0.36 10.2 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF3584 PF12128.8 EHT99013.1 - 0.31 8.5 0.1 0.42 8.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) BPD_transp_2 PF02653.16 EHT99014.1 - 1.5e-56 191.5 31.6 1.5e-56 191.5 31.6 2.1 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component DUF3382 PF11862.8 EHT99014.1 - 6.7e-22 77.6 5.9 6.7e-22 77.6 5.9 4.2 5 2 0 5 5 5 1 Domain of unknown function (DUF3382) BPD_transp_2 PF02653.16 EHT99015.1 - 1.1e-66 224.8 44.1 1.3e-66 224.6 44.1 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component Protoglobin PF11563.8 EHT99015.1 - 0.12 12.3 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Protoglobin Peripla_BP_6 PF13458.6 EHT99016.1 - 2.5e-60 205.0 8.1 2.8e-60 204.8 8.1 1.0 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 EHT99016.1 - 7.9e-24 84.4 0.0 1.1e-23 83.9 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_5 PF13433.6 EHT99016.1 - 9.8e-21 74.1 0.0 1.2e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_4 PF13407.6 EHT99016.1 - 0.0065 16.1 3.9 0.0065 16.1 3.9 2.2 1 1 0 1 1 1 1 Periplasmic binding protein domain Bmp PF02608.14 EHT99016.1 - 0.07 12.1 0.7 1.5 7.7 0.0 2.3 2 0 0 2 2 2 0 ABC transporter substrate-binding protein PnrA-like ZnuA PF01297.17 EHT99016.1 - 0.076 12.4 0.0 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic PGM_PMM_I PF02878.16 EHT99016.1 - 0.097 12.4 0.6 0.49 10.1 0.0 2.2 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I DDE_3 PF13358.6 EHT99017.1 - 1.1e-22 80.3 0.0 1.9e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 EHT99017.1 - 1.1e-10 41.0 1.0 3.6e-09 36.2 0.1 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 EHT99017.1 - 4.1e-09 36.9 1.1 2.8e-08 34.3 0.3 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 EHT99017.1 - 4e-07 30.0 1.2 1.1e-06 28.6 0.3 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHT99017.1 - 1.4e-05 25.1 0.3 0.0002 21.4 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_33 PF13592.6 EHT99017.1 - 6e-05 22.6 5.4 8.3e-05 22.1 0.5 3.0 3 0 0 3 3 3 1 Winged helix-turn helix LZ_Tnp_IS481 PF13011.6 EHT99017.1 - 0.029 14.9 0.2 0.061 13.8 0.2 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 HTH_38 PF13936.6 EHT99017.1 - 0.052 13.3 0.6 0.16 11.8 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain PanZ PF12568.8 EHT99018.1 - 9.9e-46 154.6 0.3 1.1e-45 154.5 0.3 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_1 PF00583.25 EHT99018.1 - 0.0038 17.5 0.0 0.0043 17.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EHT99018.1 - 0.011 15.7 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EHT99018.1 - 0.084 13.3 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sigma70_r4 PF04545.16 EHT99019.1 - 7.5e-18 63.8 1.2 5.4e-16 57.8 0.3 2.5 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 EHT99019.1 - 1.1e-16 60.3 0.0 2.1e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r1_2 PF00140.20 EHT99019.1 - 0.00057 19.8 0.1 0.0015 18.5 0.1 1.7 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 KORA PF16509.5 EHT99019.1 - 0.0011 19.2 0.3 0.51 10.7 0.1 2.5 2 0 0 2 2 2 1 TrfB plasmid transcriptional repressor HTH_10 PF04967.12 EHT99019.1 - 0.0013 18.5 0.0 0.064 13.1 0.0 2.8 2 0 0 2 2 2 1 HTH DNA binding domain HTH_AsnC-type PF13404.6 EHT99019.1 - 0.0044 16.8 0.5 0.17 11.7 0.1 2.6 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain IF2_N PF04760.15 EHT99019.1 - 0.0091 15.8 0.7 7.4 6.5 0.1 3.1 3 0 0 3 3 3 2 Translation initiation factor IF-2, N-terminal region GerE PF00196.19 EHT99019.1 - 0.023 14.2 0.0 1.1 8.9 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family UCR_14kD PF02271.16 EHT99019.1 - 0.032 14.2 0.1 0.5 10.4 0.0 2.5 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase complex 14kD subunit HTH_3 PF01381.22 EHT99019.1 - 0.04 14.0 0.1 0.3 11.2 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix Sigma70_r3 PF04539.16 EHT99019.1 - 0.04 14.0 1.4 9.2 6.4 0.1 2.6 2 0 0 2 2 2 0 Sigma-70 region 3 HTH_25 PF13413.6 EHT99019.1 - 0.045 13.6 2.0 0.78 9.6 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain GntR PF00392.21 EHT99019.1 - 0.061 13.0 0.5 0.75 9.5 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family ENT PF03735.14 EHT99019.1 - 0.089 12.9 2.3 17 5.5 0.2 3.2 2 1 0 2 2 2 0 ENT domain DUF5412 PF17428.2 EHT99019.1 - 0.12 12.2 0.1 0.24 11.2 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5412) HTH_DeoR PF08220.12 EHT99019.1 - 0.14 11.9 0.4 0.74 9.6 0.1 2.2 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain HTH_31 PF13560.6 EHT99019.1 - 0.15 12.4 0.4 8.6 6.8 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain 2Fe-2S_thioredx PF01257.19 EHT99019.1 - 0.15 11.9 0.0 0.58 10.0 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like [2Fe-2S] ferredoxin FtsX_ECD PF18075.1 EHT99020.1 - 1.3e-16 61.0 0.1 2e-16 60.4 0.1 1.3 1 0 0 1 1 1 1 FtsX extracellular domain FtsX PF02687.21 EHT99020.1 - 3.8e-05 24.1 6.2 3.8e-05 24.1 6.2 3.0 3 0 0 3 3 3 1 FtsX-like permease family DUF1418 PF07214.12 EHT99020.1 - 0.005 16.7 2.4 0.87 9.5 0.2 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF1418) DUF1294 PF06961.13 EHT99020.1 - 0.038 14.2 2.6 1.9 8.8 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1294) SCIMP PF15050.6 EHT99020.1 - 0.049 14.1 0.1 0.099 13.1 0.1 1.5 1 0 0 1 1 1 0 SCIMP protein ABC_tran PF00005.27 EHT99021.1 - 7.3e-37 126.9 0.0 9.3e-37 126.6 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EHT99021.1 - 4e-06 26.9 0.3 0.011 15.6 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EHT99021.1 - 6.2e-05 22.7 0.0 0.00016 21.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EHT99021.1 - 0.00038 20.4 0.0 0.00071 19.5 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EHT99021.1 - 0.00089 19.7 0.0 0.0013 19.1 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EHT99021.1 - 0.0045 17.5 0.0 0.0072 16.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EHT99021.1 - 0.015 14.9 0.1 0.36 10.4 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EHT99021.1 - 0.045 14.0 0.3 0.17 12.2 0.1 1.9 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EHT99021.1 - 0.052 13.6 0.0 0.13 12.3 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 EHT99021.1 - 0.057 13.6 0.2 0.16 12.1 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EHT99021.1 - 0.091 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EHT99021.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 NTPase SMC_N PF02463.19 EHT99021.1 - 0.22 11.0 0.0 2.1 7.8 0.0 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain SRP54 PF00448.22 EHT99022.1 - 6.6e-79 264.1 1.7 6.6e-79 264.1 1.7 1.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 EHT99022.1 - 4.6e-13 49.2 0.2 1.9e-12 47.2 0.2 2.1 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain Zeta_toxin PF06414.12 EHT99022.1 - 3e-08 33.2 0.1 5.3e-08 32.4 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_30 PF13604.6 EHT99022.1 - 2.4e-05 24.1 1.4 5.1e-05 23.1 1.4 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EHT99022.1 - 3.4e-05 24.3 0.2 8.3e-05 23.0 0.2 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EHT99022.1 - 0.00019 21.6 0.1 0.00043 20.5 0.1 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EHT99022.1 - 0.00024 21.6 0.9 0.00042 20.9 0.1 1.8 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 EHT99022.1 - 0.00026 21.3 0.1 0.00095 19.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 EHT99022.1 - 0.0034 17.3 0.0 0.0079 16.1 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase Thymidylate_kin PF02223.17 EHT99022.1 - 0.006 16.3 0.6 0.083 12.6 0.1 2.3 2 0 0 2 2 2 1 Thymidylate kinase AAA PF00004.29 EHT99022.1 - 0.0092 16.4 0.1 0.019 15.4 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EHT99022.1 - 0.0094 16.0 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EHT99022.1 - 0.01 16.2 0.1 0.01 16.2 0.1 3.1 2 2 0 2 2 1 0 AAA ATPase domain CbiA PF01656.23 EHT99022.1 - 0.011 15.8 0.5 0.13 12.3 0.5 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EHT99022.1 - 0.025 14.5 0.2 0.043 13.7 0.2 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EHT99022.1 - 0.035 13.4 0.2 0.05 12.8 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MMR_HSR1 PF01926.23 EHT99022.1 - 0.055 13.6 0.5 0.21 11.7 0.5 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 EHT99022.1 - 0.076 12.7 0.0 0.42 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain VirE PF05272.11 EHT99022.1 - 0.089 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Virulence-associated protein E NTPase_1 PF03266.15 EHT99022.1 - 0.2 11.5 1.4 1.6 8.6 0.3 2.2 1 1 1 2 2 2 0 NTPase Cons_hypoth95 PF03602.15 EHT99023.1 - 1.2e-61 207.5 0.0 1.4e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 EHT99023.1 - 1.7e-05 24.4 0.0 2.3e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain TetR_C_28 PF17937.1 EHT99023.1 - 0.05 14.1 0.0 0.12 12.9 0.0 1.6 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain RrnaAD PF00398.20 EHT99023.1 - 0.059 12.4 0.0 0.08 12.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase RsmJ PF04378.13 EHT99023.1 - 0.11 11.7 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA large subunit methyltransferase D, RlmJ MethyltransfD12 PF02086.15 EHT99023.1 - 0.12 12.0 0.0 5.1 6.7 0.0 2.1 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase DUF1145 PF06611.12 EHT99024.1 - 4.8e-26 90.5 9.6 7.7e-26 89.8 9.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1145) S1FA PF04689.13 EHT99024.1 - 2.5 8.3 5.4 15 5.8 0.0 2.9 3 0 0 3 3 3 0 DNA binding protein S1FA DUF2500 PF10694.9 EHT99025.1 - 1.3e-33 115.8 0.1 1.5e-33 115.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2500) DUF2973 PF11189.8 EHT99025.1 - 0.57 10.3 2.0 0.98 9.6 2.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2973) YhhN PF07947.14 EHT99026.1 - 2.3e-39 134.9 18.1 2.8e-39 134.7 18.1 1.1 1 0 0 1 1 1 1 YhhN family PalH PF08733.10 EHT99026.1 - 0.002 17.2 1.2 0.002 17.2 1.2 1.8 1 1 1 2 2 2 1 PalH/RIM21 E1-E2_ATPase PF00122.20 EHT99027.1 - 1.9e-44 151.4 0.0 1.9e-44 151.4 0.0 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EHT99027.1 - 1.3e-39 136.7 2.2 2.1e-39 136.0 2.2 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EHT99027.1 - 3.8e-09 36.9 0.0 7.6e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EHT99027.1 - 3.5e-06 27.0 0.2 3.2e-05 23.8 0.4 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase TusA PF01206.17 EHT99028.1 - 3.8e-24 84.3 0.0 4.2e-24 84.1 0.0 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA DUF2249 PF10006.9 EHT99028.1 - 9e-05 22.3 0.1 0.00011 22.0 0.1 1.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2249) Vut_1 PF02592.15 EHT99029.1 - 2.2e-33 115.7 12.8 3.6e-33 115.0 10.4 1.9 2 0 0 2 2 2 1 Putative vitamin uptake transporter DcrB PF08786.11 EHT99030.1 - 4.3e-32 110.9 0.9 5.9e-32 110.5 0.9 1.2 1 0 0 1 1 1 1 DcrB DUF1454 PF07305.12 EHT99030.1 - 0.00092 18.7 0.1 0.0017 17.8 0.1 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF1454) PsbP PF01789.16 EHT99030.1 - 0.0034 17.5 0.3 0.0047 17.1 0.3 1.2 1 0 0 1 1 1 1 PsbP DUF2090 PF09863.9 EHT99031.1 - 6.4e-136 452.4 0.2 8.5e-136 452.0 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2090) PfkB PF00294.24 EHT99031.1 - 1.6e-41 142.6 0.0 3.8e-41 141.4 0.0 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase DUF4148 PF13663.6 EHT99031.1 - 0.064 13.4 0.1 0.23 11.7 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) TPP_enzyme_C PF02775.21 EHT99032.1 - 8.8e-40 136.0 0.0 4.6e-39 133.7 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.18 EHT99032.1 - 1.5e-34 119.1 0.0 7.6e-34 116.8 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EHT99032.1 - 1.4e-32 112.3 0.0 5.8e-32 110.3 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DUF2974 PF11187.8 EHT99032.1 - 0.011 15.3 0.1 2.5 7.6 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2974) CO_dh PF02552.16 EHT99032.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit GFO_IDH_MocA PF01408.22 EHT99033.1 - 3.8e-26 92.3 0.1 5.6e-26 91.7 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EHT99033.1 - 5e-08 33.0 0.0 7.9e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain 2-Hacid_dh_C PF02826.19 EHT99033.1 - 0.0059 16.0 0.1 0.01 15.2 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EHT99033.1 - 0.073 13.7 0.0 0.19 12.3 0.1 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AP_endonuc_2 PF01261.24 EHT99034.1 - 1.8e-24 86.4 0.2 4.2e-24 85.2 0.1 1.6 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel AP_endonuc_2_N PF07582.12 EHT99034.1 - 0.00019 21.0 0.0 0.0013 18.4 0.0 2.3 2 0 0 2 2 2 1 AP endonuclease family 2 C terminus SIS PF01380.22 EHT99035.1 - 4.3e-24 84.8 0.0 7.2e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 SIS domain HTH_6 PF01418.17 EHT99035.1 - 1.2e-12 47.6 0.8 2.3e-12 46.7 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain, rpiR family SIS_2 PF13580.6 EHT99035.1 - 0.00072 19.6 0.0 0.0026 17.8 0.0 2.0 2 0 0 2 2 2 1 SIS domain DASH_Dad3 PF08656.10 EHT99035.1 - 0.0065 16.5 0.3 2.9 8.0 0.0 2.4 2 0 0 2 2 2 2 DASH complex subunit Dad3 KduI PF04962.12 EHT99036.1 - 8.7e-109 362.8 0.1 9.9e-109 362.7 0.1 1.0 1 0 0 1 1 1 1 KduI/IolB family VGCC_alpha2 PF08473.11 EHT99036.1 - 0.16 10.7 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Neuronal voltage-dependent calcium channel alpha 2acd Aldedh PF00171.22 EHT99037.1 - 2.7e-139 464.7 0.0 3.2e-139 464.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EHT99037.1 - 0.0021 17.2 0.0 0.0037 16.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Xan_ur_permease PF00860.20 EHT99038.1 - 1.3e-81 274.3 39.8 1.5e-81 274.1 39.8 1.1 1 0 0 1 1 1 1 Permease family DUF5423 PF17461.2 EHT99038.1 - 0.055 12.3 2.0 0.11 11.4 2.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5423) ApoO PF09769.9 EHT99038.1 - 3.6 7.6 4.5 3.9 7.4 0.6 2.5 2 0 0 2 2 2 0 Apolipoprotein O YfhO PF09586.10 EHT99038.1 - 4.4 5.4 5.6 0.34 9.1 0.7 1.5 2 0 0 2 2 2 0 Bacterial membrane protein YfhO AI-2E_transport PF01594.16 EHT99039.1 - 1.9e-64 217.9 41.8 2.2e-64 217.7 41.8 1.0 1 0 0 1 1 1 1 AI-2E family transporter GntR PF00392.21 EHT99040.1 - 1.4e-20 72.6 0.1 4.3e-20 71.1 0.1 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family FCD PF07729.12 EHT99040.1 - 2.7e-20 73.0 12.5 4.7e-20 72.3 12.5 1.4 1 0 0 1 1 1 1 FCD domain HTH_IclR PF09339.10 EHT99040.1 - 4.9e-05 23.0 0.1 0.00012 21.8 0.1 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain Fe_dep_repress PF01325.19 EHT99040.1 - 0.00018 21.6 0.0 0.0003 20.9 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_11 PF08279.12 EHT99040.1 - 0.00019 21.3 0.1 0.00042 20.2 0.1 1.5 1 0 0 1 1 1 1 HTH domain TrmB PF01978.19 EHT99040.1 - 0.00028 20.7 0.0 0.0006 19.7 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB LexA_DNA_bind PF01726.16 EHT99040.1 - 0.0049 16.6 0.0 0.012 15.3 0.0 1.8 1 0 0 1 1 1 1 LexA DNA binding domain DprA_WH PF17782.1 EHT99040.1 - 0.0059 16.7 0.1 0.013 15.5 0.1 1.6 1 0 0 1 1 1 1 DprA winged helix domain HTH_24 PF13412.6 EHT99040.1 - 0.009 15.6 0.0 0.02 14.4 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_10 PF04967.12 EHT99040.1 - 0.0094 15.7 0.1 0.18 11.6 0.0 2.6 3 0 0 3 3 3 1 HTH DNA binding domain HTH_46 PF15977.5 EHT99040.1 - 0.0096 15.9 0.0 0.024 14.6 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA binding CRISPR_Cse1 PF09481.10 EHT99040.1 - 0.012 14.8 0.1 0.015 14.4 0.1 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Cse1 (CRISPR_cse1) HTH_36 PF13730.6 EHT99040.1 - 0.024 14.6 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 EHT99040.1 - 0.025 14.6 0.0 0.059 13.3 0.0 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain MarR PF01047.22 EHT99040.1 - 0.032 14.2 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 MarR family MarR_2 PF12802.7 EHT99040.1 - 0.062 13.2 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 MarR family HTH_AsnC-type PF13404.6 EHT99040.1 - 0.07 13.0 0.3 0.16 11.8 0.3 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Rrf2 PF02082.20 EHT99040.1 - 0.078 13.3 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator HTH_5 PF01022.20 EHT99040.1 - 0.14 12.0 0.0 0.39 10.6 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family UxuA PF03786.13 EHT99041.1 - 1.9e-146 487.4 0.0 2.2e-146 487.2 0.0 1.0 1 0 0 1 1 1 1 D-mannonate dehydratase (UxuA) AP_endonuc_2 PF01261.24 EHT99041.1 - 2e-09 37.2 0.0 4.6e-09 36.0 0.0 1.6 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Catalase-rel PF06628.12 EHT99041.1 - 0.015 15.5 0.0 0.065 13.5 0.0 2.0 2 0 0 2 2 2 0 Catalase-related immune-responsive EAL PF00563.20 EHT99042.1 - 2.4e-63 213.8 0.0 3.3e-63 213.4 0.0 1.2 1 0 0 1 1 1 1 EAL domain CSS-motif PF12792.7 EHT99042.1 - 9.1e-31 107.0 0.1 1.3e-30 106.5 0.1 1.2 1 0 0 1 1 1 1 CSS motif domain associated with EAL Sugar_tr PF00083.24 EHT99044.1 - 3.1e-69 234.0 23.2 3.1e-69 234.0 23.2 1.8 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 EHT99044.1 - 2.5e-36 125.3 39.5 5.2e-26 91.4 15.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Osmo_CC PF08946.10 EHT99044.1 - 6.9e-22 77.4 9.9 1.2e-21 76.7 9.9 1.4 1 0 0 1 1 1 1 Osmosensory transporter coiled coil TRI12 PF06609.13 EHT99044.1 - 0.0021 16.6 7.2 0.0021 16.6 7.2 2.2 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) TssO PF17561.2 EHT99044.1 - 0.015 15.4 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 Type VI secretion system, TssO MerR-DNA-bind PF09278.11 EHT99044.1 - 0.033 14.7 1.4 0.07 13.7 1.4 1.5 1 0 0 1 1 1 0 MerR, DNA binding DUF1043 PF06295.12 EHT99044.1 - 0.034 14.1 0.0 0.034 14.1 0.0 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF1043) DUF1192 PF06698.11 EHT99044.1 - 0.047 13.7 1.0 0.11 12.6 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Prefoldin_2 PF01920.20 EHT99044.1 - 0.071 13.1 0.8 0.12 12.3 0.8 1.3 1 0 0 1 1 1 0 Prefoldin subunit ERM PF00769.19 EHT99044.1 - 0.17 11.7 3.0 0.24 11.2 3.0 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family FlxA PF14282.6 EHT99044.1 - 0.2 11.7 0.8 0.3 11.1 0.8 1.2 1 0 0 1 1 1 0 FlxA-like protein Med4 PF10018.9 EHT99044.1 - 0.29 10.8 2.2 0.59 9.8 2.2 1.4 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF1843 PF08898.10 EHT99044.1 - 0.44 11.1 2.9 0.9 10.1 2.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) Prefoldin PF02996.17 EHT99044.1 - 0.7 9.8 3.7 1.6 8.7 3.7 1.6 1 1 0 1 1 1 0 Prefoldin subunit ALAD PF00490.21 EHT99045.1 - 3.4e-134 447.0 0.8 3.9e-134 446.8 0.8 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase AP_endonuc_2 PF01261.24 EHT99045.1 - 0.096 12.1 0.1 14 5.0 0.0 2.3 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel HTH_18 PF12833.7 EHT99046.1 - 3e-16 59.4 0.0 4.3e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 EHT99046.1 - 1.7e-14 53.5 0.2 6.4e-07 29.3 0.0 2.2 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family DUF362 PF04015.12 EHT99046.1 - 0.0027 18.0 0.0 0.0028 17.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF362) HTH_3 PF01381.22 EHT99046.1 - 0.037 14.1 0.1 0.18 11.9 0.0 2.1 2 1 1 3 3 3 0 Helix-turn-helix FRG2 PF15315.6 EHT99046.1 - 0.11 12.6 0.4 0.16 12.2 0.4 1.2 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 QueH PF02677.14 EHT99047.1 - 5.1e-64 215.6 0.7 6.1e-64 215.3 0.7 1.1 1 0 0 1 1 1 1 Epoxyqueuosine reductase QueH adh_short PF00106.25 EHT99048.1 - 6e-27 94.4 0.0 8.1e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EHT99048.1 - 9.5e-21 74.4 0.0 1.2e-20 74.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EHT99048.1 - 0.00023 20.7 0.0 0.0004 19.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EHT99048.1 - 0.00042 20.3 0.0 0.00063 19.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EHT99048.1 - 0.0026 16.9 0.0 0.0036 16.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 EHT99048.1 - 0.0067 16.4 0.7 0.054 13.4 0.7 1.9 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 EHT99048.1 - 0.018 14.8 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase zf-UBP_var PF17807.1 EHT99048.1 - 0.07 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Variant UBP zinc finger NmrA PF05368.13 EHT99048.1 - 0.15 11.6 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family HTH_6 PF01418.17 EHT99050.1 - 5.3e-08 32.7 0.1 1.5e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain, rpiR family HTH_36 PF13730.6 EHT99050.1 - 0.0063 16.4 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain SIS PF01380.22 EHT99050.1 - 0.031 14.1 0.0 0.047 13.5 0.0 1.3 1 0 0 1 1 1 0 SIS domain Peptidase_M15 PF01427.17 EHT99051.1 - 1.8e-59 200.9 0.0 4.6e-59 199.6 0.0 1.5 1 1 0 1 1 1 1 D-ala-D-ala dipeptidase VanY PF02557.17 EHT99051.1 - 2.8e-07 30.4 0.2 9.7e-07 28.6 0.2 1.9 1 1 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Peptidase_M15_4 PF13539.6 EHT99051.1 - 0.12 12.9 0.3 0.25 11.9 0.3 1.7 1 1 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase SBP_bac_5 PF00496.22 EHT99052.1 - 1.1e-94 317.5 4.3 1.6e-94 316.9 4.3 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle BPD_transp_1 PF00528.22 EHT99053.1 - 4.2e-45 153.8 12.5 4.2e-45 153.8 12.5 1.5 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 EHT99054.1 - 5.5e-32 111.0 8.4 5.5e-32 111.0 8.4 1.9 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 EHT99054.1 - 1.2e-06 28.4 1.0 1.2e-06 28.4 1.0 3.4 4 0 0 4 4 4 1 N-terminal TM domain of oligopeptide transport permease C ABC_tran PF00005.27 EHT99055.1 - 1.6e-25 90.2 0.0 2.2e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EHT99055.1 - 2.1e-14 53.8 0.4 4e-14 52.9 0.4 1.5 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 EHT99055.1 - 9.2e-07 28.9 0.0 4.5e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EHT99055.1 - 5e-06 26.1 0.1 8.4e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EHT99055.1 - 0.0083 16.5 0.1 0.015 15.6 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EHT99055.1 - 0.027 14.7 0.0 0.073 13.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EHT99055.1 - 0.043 13.3 0.0 0.079 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DEAD PF00270.29 EHT99055.1 - 0.045 13.5 0.1 0.098 12.4 0.1 1.5 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_29 PF13555.6 EHT99055.1 - 0.067 12.9 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain HDC PF02329.16 EHT99055.1 - 0.11 11.4 0.0 0.3 10.1 0.0 1.5 2 0 0 2 2 2 0 Histidine carboxylase PI chain ABC_tran PF00005.27 EHT99056.1 - 1.5e-28 100.0 0.0 2.2e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EHT99056.1 - 3.6e-18 65.8 0.0 7.2e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 EHT99056.1 - 8.8e-10 38.9 0.1 5.9e-07 29.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EHT99056.1 - 6.4e-07 29.7 0.8 5.8e-06 26.6 0.8 2.0 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 EHT99056.1 - 1.9e-05 24.2 0.2 0.0018 17.7 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 EHT99056.1 - 2.7e-05 24.6 0.1 0.04 14.4 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EHT99056.1 - 0.0001 22.7 0.1 0.00019 21.9 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EHT99056.1 - 0.0014 18.6 0.2 0.0026 17.7 0.2 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 EHT99056.1 - 0.0016 18.1 0.0 0.0042 16.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EHT99056.1 - 0.0051 16.2 0.1 0.0088 15.4 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 EHT99056.1 - 0.0062 16.2 0.3 0.011 15.4 0.3 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 EHT99056.1 - 0.013 15.2 0.7 0.58 9.9 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein NB-ARC PF00931.22 EHT99056.1 - 0.021 14.0 0.0 0.035 13.3 0.0 1.6 1 1 0 1 1 1 0 NB-ARC domain ATP-synt_ab PF00006.25 EHT99056.1 - 0.026 14.2 0.0 0.044 13.4 0.0 1.4 2 0 0 2 2 1 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.22 EHT99056.1 - 0.029 14.8 0.1 0.06 13.7 0.1 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 EHT99056.1 - 0.029 14.1 0.1 1.1 9.0 0.1 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.14 EHT99056.1 - 0.03 14.3 0.3 0.32 11.0 0.2 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 EHT99056.1 - 0.064 13.2 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 EHT99056.1 - 0.071 12.5 0.7 8.1 5.8 0.2 2.4 2 1 0 2 2 2 0 Bacterial TniB protein DUF87 PF01935.17 EHT99056.1 - 0.086 12.9 0.1 0.22 11.6 0.1 1.6 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_33 PF13671.6 EHT99056.1 - 0.092 12.9 0.1 0.19 11.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain Propep_M14 PF02244.16 EHT99056.1 - 0.11 13.0 0.2 0.22 12.0 0.2 1.4 1 0 0 1 1 1 0 Carboxypeptidase activation peptide MMR_HSR1 PF01926.23 EHT99056.1 - 0.12 12.4 0.1 0.25 11.4 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 EHT99056.1 - 0.12 12.6 0.0 0.61 10.4 0.0 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 EHT99056.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain PRK PF00485.18 EHT99056.1 - 0.19 11.5 0.1 0.37 10.5 0.1 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EHT99056.1 - 0.19 12.2 0.1 0.54 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EHT99056.1 - 0.2 12.1 0.0 0.36 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 EHT99056.1 - 0.24 10.1 1.1 2.6 6.8 0.1 2.3 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_15 PF13175.6 EHT99056.1 - 0.32 10.7 0.2 1.7 8.2 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_13 PF13166.6 EHT99056.1 - 2.8 6.5 4.6 1.2 7.7 0.3 2.2 2 1 1 3 3 3 0 AAA domain DAO PF01266.24 EHT99057.1 - 2.8e-72 244.2 1.5 3.3e-72 244.0 1.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EHT99057.1 - 2e-09 37.0 2.7 3.2e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 EHT99057.1 - 1e-07 32.4 0.0 0.00011 22.7 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EHT99057.1 - 1.5e-07 31.0 0.1 0.00062 19.1 0.5 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EHT99057.1 - 2.4e-07 30.9 0.2 5e-06 26.6 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 EHT99057.1 - 2.8e-05 23.8 0.4 0.0002 21.0 0.3 2.1 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Amino_oxidase PF01593.24 EHT99057.1 - 0.00012 21.6 0.0 0.17 11.2 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EHT99057.1 - 0.00013 20.8 0.7 0.16 10.6 0.5 2.4 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_3 PF01494.19 EHT99057.1 - 0.00046 19.6 1.0 0.021 14.1 0.5 2.3 2 0 0 2 2 2 1 FAD binding domain UDPG_MGDP_dh_N PF03721.14 EHT99057.1 - 0.0017 18.0 0.2 0.0037 16.9 0.2 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_oxidored PF12831.7 EHT99057.1 - 0.0044 16.4 1.3 2 7.6 1.8 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EHT99057.1 - 0.0053 15.7 3.2 0.06 12.2 1.4 2.2 2 0 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.17 EHT99057.1 - 0.0089 15.3 0.4 0.051 12.8 0.5 2.0 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 EHT99057.1 - 0.027 13.8 0.5 0.045 13.0 0.5 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 EHT99057.1 - 0.031 14.5 0.1 0.072 13.4 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 EHT99057.1 - 0.053 13.4 0.9 0.12 12.2 0.5 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 EHT99057.1 - 0.062 12.4 0.6 0.31 10.1 0.7 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Glyco_transf_4 PF13439.6 EHT99057.1 - 0.072 13.1 0.3 0.28 11.2 0.0 2.1 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Transglut_core PF01841.19 EHT99057.1 - 0.12 12.9 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily Pyr_redox_3 PF13738.6 EHT99057.1 - 0.12 11.6 0.0 0.67 9.2 0.2 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 EHT99057.1 - 0.19 11.7 0.3 0.35 10.9 0.3 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.14 EHT99058.1 - 6.1e-155 515.9 0.0 6.8e-155 515.8 0.0 1.0 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 EHT99058.1 - 3.1e-12 46.3 0.8 4.9e-09 35.8 0.1 3.0 2 1 0 3 3 3 2 FAD binding domain DAO PF01266.24 EHT99058.1 - 1e-10 41.8 0.8 8.6e-07 28.9 0.1 2.8 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EHT99058.1 - 1.7e-09 37.3 0.0 7.1e-09 35.3 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EHT99058.1 - 6.9e-09 35.4 0.5 0.0077 15.5 0.4 3.2 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EHT99058.1 - 3.1e-08 33.4 0.0 4.9e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EHT99058.1 - 6.3e-08 32.1 3.2 0.00021 20.5 1.1 2.9 2 1 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EHT99058.1 - 1e-06 28.9 1.0 2.5e-06 27.6 1.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EHT99058.1 - 1.9e-05 23.9 0.1 0.0013 17.8 0.2 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Amino_oxidase PF01593.24 EHT99058.1 - 0.00093 18.6 0.1 0.32 10.2 0.0 2.7 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 EHT99058.1 - 0.0011 18.9 0.0 0.0043 17.0 0.0 2.0 1 1 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.17 EHT99058.1 - 0.0079 15.5 0.0 0.016 14.5 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 EHT99058.1 - 0.017 15.7 0.1 0.88 10.2 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EHT99058.1 - 0.027 13.7 0.1 0.13 11.4 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain AlaDh_PNT_C PF01262.21 EHT99058.1 - 0.045 13.0 0.0 0.075 12.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PHO4 PF01384.20 EHT99059.1 - 5.5e-90 301.8 13.3 6.6e-90 301.5 13.3 1.1 1 0 0 1 1 1 1 Phosphate transporter family Myc_target_1 PF15179.6 EHT99059.1 - 0.00047 20.1 2.3 0.0082 16.1 0.0 2.7 2 0 0 2 2 2 1 Myc target protein 1 UspB PF10625.9 EHT99060.1 - 1.3e-53 179.4 0.5 1.5e-53 179.3 0.5 1.0 1 0 0 1 1 1 1 Universal stress protein B (UspB) Usp PF00582.26 EHT99061.1 - 1.1e-21 77.8 0.0 1.2e-21 77.7 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family SAM_MT PF04445.13 EHT99062.1 - 6.4e-107 356.2 0.0 7.3e-107 356.0 0.0 1.0 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase Peptidase_M3 PF01432.20 EHT99063.1 - 1.2e-171 572.1 0.0 1.5e-171 571.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Phage_integrase PF00589.22 EHT99064.1 - 4e-16 59.3 0.0 1e-15 58.0 0.0 1.6 2 0 0 2 2 2 1 Phage integrase family Arm-DNA-bind_3 PF13356.6 EHT99064.1 - 4.5e-13 49.4 0.1 9.7e-13 48.3 0.1 1.6 1 0 0 1 1 1 1 Arm DNA-binding domain Phage_int_SAM_3 PF14659.6 EHT99064.1 - 0.0005 20.3 0.0 0.0016 18.7 0.0 1.9 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_AlpA PF05930.12 EHT99065.1 - 7.1e-10 38.6 0.1 8.9e-10 38.2 0.1 1.1 1 0 0 1 1 1 1 Prophage CP4-57 regulatory protein (AlpA) Phage_ASH PF10554.9 EHT99066.1 - 1.1e-29 102.9 0.1 1.9e-29 102.1 0.1 1.4 1 0 0 1 1 1 1 Ash protein family Phage_integrase PF00589.22 EHT99067.1 - 2e-09 37.5 0.2 6.8e-08 32.5 0.2 2.1 1 1 0 1 1 1 1 Phage integrase family Toprim_3 PF13362.6 EHT99069.1 - 7.9e-14 51.8 1.9 1.7e-13 50.7 0.7 2.3 2 0 0 2 2 2 1 Toprim domain Prim_Zn_Ribbon PF08273.12 EHT99069.1 - 9.8e-13 48.2 6.7 2e-12 47.2 6.7 1.5 1 0 0 1 1 1 1 Zinc-binding domain of primase-helicase Pox_D5 PF03288.16 EHT99069.1 - 8.4e-10 39.0 0.0 4.3e-09 36.7 0.0 2.2 3 0 0 3 3 3 1 Poxvirus D5 protein-like D5_N PF08706.11 EHT99069.1 - 2.9e-08 34.1 0.0 1.2e-07 32.2 0.0 2.0 2 0 0 2 2 2 1 D5 N terminal like Toprim_2 PF13155.6 EHT99069.1 - 0.0002 21.7 0.1 0.00064 20.1 0.1 1.9 1 0 0 1 1 1 1 Toprim-like Zn_Tnp_IS1595 PF12760.7 EHT99069.1 - 0.00035 20.5 2.0 0.00076 19.4 2.0 1.5 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Toprim_4 PF13662.6 EHT99069.1 - 0.00043 20.7 0.1 0.0016 18.9 0.1 2.0 1 0 0 1 1 1 1 Toprim domain PALP PF00291.25 EHT99069.1 - 0.00059 19.3 0.1 0.001 18.6 0.1 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TF_Zn_Ribbon PF08271.12 EHT99069.1 - 0.0052 16.3 2.3 0.01 15.3 2.3 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding RFX_DNA_binding PF02257.15 EHT99069.1 - 0.014 16.0 0.1 0.032 14.8 0.1 1.6 1 0 0 1 1 1 0 RFX DNA-binding domain zf-CHC2 PF01807.20 EHT99069.1 - 0.022 14.6 0.0 0.068 13.0 0.0 1.8 1 0 0 1 1 1 0 CHC2 zinc finger Lar_restr_allev PF14354.6 EHT99069.1 - 0.037 14.4 0.6 0.11 12.8 0.6 1.8 1 0 0 1 1 1 0 Restriction alleviation protein Lar Nudix_N_2 PF14803.6 EHT99069.1 - 0.054 13.4 3.2 0.14 12.1 3.2 1.7 1 0 0 1 1 1 0 Nudix N-terminal AAA_29 PF13555.6 EHT99069.1 - 0.058 13.2 0.2 0.47 10.2 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain RhoGAP-FF1 PF16512.5 EHT99069.1 - 0.091 13.4 0.0 7.4 7.3 0.0 2.6 2 0 0 2 2 2 0 p190-A and -B Rho GAPs FF domain PhnA_Zn_Ribbon PF08274.12 EHT99069.1 - 0.15 12.1 0.2 0.34 10.9 0.2 1.6 1 0 0 1 1 1 0 PhnA Zinc-Ribbon zf-RRN7 PF11781.8 EHT99069.1 - 0.66 9.7 8.2 2.2 8.0 8.2 1.9 1 1 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 UPF0242 PF06785.11 EHT99071.1 - 0.17 12.0 5.2 0.2 11.8 5.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TPX2 PF06886.11 EHT99071.1 - 0.63 10.3 10.3 0.93 9.8 10.3 1.3 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) DNA_Packaging_2 PF11123.8 EHT99073.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 DNA packaging protein Gp138_N PF18352.1 EHT99075.1 - 5.5e-30 103.3 0.2 1.7e-29 101.8 0.0 1.9 2 0 0 2 2 2 1 Phage protein Gp138 N-terminal domain RsmJ PF04378.13 EHT99077.1 - 9.1e-111 368.9 0.0 1.1e-110 368.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA large subunit methyltransferase D, RlmJ Cons_hypoth95 PF03602.15 EHT99077.1 - 0.01 15.5 0.0 0.21 11.2 0.0 2.4 3 0 0 3 3 3 1 Conserved hypothetical protein 95 CPBP PF02517.16 EHT99078.1 - 9.5e-20 70.8 10.5 9.5e-20 70.8 10.5 2.8 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease DUF2953 PF11167.8 EHT99078.1 - 0.76 9.9 6.0 3.4 7.8 0.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2953) DUF5413 PF17434.2 EHT99078.1 - 1.9 8.8 8.5 0.071 13.4 1.1 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5413) 5TM-5TMR_LYT PF07694.12 EHT99078.1 - 8.8 5.8 15.5 1.3 8.5 7.7 2.4 2 0 0 2 2 2 0 5TMR of 5TMR-LYT Lactamase_B_2 PF12706.7 EHT99079.1 - 4.3e-21 75.4 0.0 1.3e-11 44.4 0.0 2.1 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EHT99079.1 - 3.5e-11 43.5 0.1 7.5e-11 42.4 0.1 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 EHT99079.1 - 3.1e-05 23.6 0.0 6.3e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 tRNase Z endonuclease Pyr_redox_2 PF07992.14 EHT99080.1 - 1.4e-70 237.9 1.6 2.2e-70 237.2 1.6 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EHT99080.1 - 1.7e-37 128.0 1.3 5e-36 123.3 0.4 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EHT99080.1 - 7.7e-17 61.6 0.0 2.3e-16 60.1 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EHT99080.1 - 1.3e-15 57.5 0.0 1.3e-15 57.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EHT99080.1 - 0.00044 19.1 0.8 1.3 7.6 0.0 3.1 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.22 EHT99080.1 - 0.013 14.6 0.2 0.05 12.7 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 EHT99080.1 - 0.046 13.1 0.1 0.19 11.0 0.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase K_oxygenase PF13434.6 EHT99080.1 - 0.17 11.0 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 EHT99080.1 - 1.5 7.8 6.4 7.8 5.5 0.1 2.7 3 0 0 3 3 3 0 FAD binding domain ROK PF00480.20 EHT99081.1 - 7.4e-22 78.2 0.0 1.7e-17 63.8 0.0 2.1 2 0 0 2 2 2 2 ROK family HTH_IclR PF09339.10 EHT99081.1 - 8.8e-05 22.2 0.1 0.00023 20.9 0.1 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_24 PF13412.6 EHT99081.1 - 0.00027 20.4 0.4 0.00048 19.6 0.4 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 EHT99081.1 - 0.0008 19.3 0.1 0.0013 18.6 0.1 1.4 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 EHT99081.1 - 0.004 17.0 0.1 0.0074 16.1 0.1 1.5 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 EHT99081.1 - 0.0049 17.3 0.0 0.0085 16.6 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain ABC_tran PF00005.27 EHT99082.1 - 1.5e-33 116.2 0.0 2.2e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EHT99082.1 - 5.1e-08 33.1 0.0 0.0032 17.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EHT99082.1 - 3.8e-05 23.2 0.1 0.00026 20.5 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 EHT99082.1 - 0.00024 21.1 0.0 0.00034 20.6 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 EHT99082.1 - 0.00092 19.6 0.3 0.0093 16.4 0.3 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EHT99082.1 - 0.0034 17.8 0.5 0.0056 17.1 0.5 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EHT99082.1 - 0.0041 17.1 0.0 0.0075 16.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase TOBE_2 PF08402.10 EHT99082.1 - 0.012 15.7 0.1 0.16 12.2 0.0 2.6 2 0 0 2 2 2 0 TOBE domain ATPase_2 PF01637.18 EHT99082.1 - 0.017 15.1 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 EHT99082.1 - 0.029 14.4 0.0 0.089 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EHT99082.1 - 0.034 14.4 0.3 0.06 13.6 0.3 1.6 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EHT99082.1 - 0.036 13.3 0.0 0.049 12.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain PapA_C PF16911.5 EHT99082.1 - 0.038 14.1 0.0 0.081 13.0 0.0 1.5 1 0 0 1 1 1 0 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus AAA_33 PF13671.6 EHT99082.1 - 0.043 14.0 1.0 0.31 11.2 1.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EHT99082.1 - 0.047 13.4 0.0 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EHT99082.1 - 0.06 13.3 0.1 0.14 12.0 0.1 1.6 2 0 0 2 2 1 0 NACHT domain AAA_25 PF13481.6 EHT99082.1 - 0.077 12.6 0.0 0.26 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EHT99082.1 - 0.1 12.4 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RuvB_N PF05496.12 EHT99082.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_15 PF13175.6 EHT99082.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 EHT99082.1 - 0.19 11.5 0.1 0.51 10.1 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 EHT99082.1 - 0.21 11.8 0.8 0.56 10.4 0.4 2.0 1 1 1 2 2 2 0 AAA domain BPD_transp_1 PF00528.22 EHT99083.1 - 5e-11 42.7 30.2 1e-07 31.9 30.2 2.5 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 EHT99084.1 - 4.1e-11 43.0 20.6 4.1e-11 43.0 20.6 2.2 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component GDPD PF03009.17 EHT99085.1 - 2.7e-33 115.8 0.0 4.1e-33 115.2 0.0 1.3 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Porin_1 PF00267.21 EHT99086.1 - 1.1e-104 350.5 21.7 1.2e-104 350.4 21.7 1.0 1 0 0 1 1 1 1 Gram-negative porin Fib_succ_major PF09603.10 EHT99086.1 - 0.087 13.4 3.1 0.16 12.6 3.1 1.5 1 0 0 1 1 1 0 Fibrobacter succinogenes major domain (Fib_succ_major) Peptidase_S9 PF00326.21 EHT99087.1 - 7.1e-06 25.7 0.0 0.005 16.3 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EHT99087.1 - 0.0031 17.4 0.1 0.018 14.9 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EHT99087.1 - 0.025 15.2 9.4 0.011 16.4 6.8 1.8 2 1 0 2 2 2 0 Alpha/beta hydrolase family DLH PF01738.18 EHT99087.1 - 0.04 13.5 0.0 6.2 6.3 0.0 2.6 2 1 1 3 3 3 0 Dienelactone hydrolase family TAT_signal PF10518.9 EHT99087.1 - 0.23 11.4 2.1 0.68 9.9 2.1 1.8 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence NST1 PF13945.6 EHT99088.1 - 0.0061 16.7 1.0 0.0074 16.4 1.0 1.1 1 0 0 1 1 1 1 Salt tolerance down-regulator 7TMR-HDED PF07697.11 EHT99088.1 - 0.035 14.2 1.3 0.036 14.2 1.3 1.1 1 0 0 1 1 1 0 7TM-HD extracellular Na_H_Exchanger PF00999.21 EHT99089.1 - 5.7e-36 124.1 39.4 9.1e-28 97.1 21.4 2.0 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family MFS_1 PF07690.16 EHT99090.1 - 3.1e-34 118.4 55.6 5.5e-31 107.8 41.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EHT99090.1 - 6e-09 35.3 13.0 6e-09 35.3 13.0 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 EHT99090.1 - 0.00076 18.9 39.4 0.005 16.2 39.2 1.9 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 EHT99090.1 - 0.027 12.8 0.4 0.027 12.8 0.4 2.9 1 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family LysR_substrate PF03466.20 EHT99091.1 - 6.1e-37 127.0 6.7 9.5e-37 126.4 6.7 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EHT99091.1 - 5.8e-19 67.8 0.5 9.7e-19 67.1 0.5 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 EHT99091.1 - 0.042 13.6 0.2 0.083 12.7 0.2 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_20 PF12840.7 EHT99091.1 - 0.089 12.9 0.1 0.4 10.8 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.6 EHT99091.1 - 0.14 12.3 0.0 0.46 10.6 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain UPF0114 PF03350.16 EHT99092.1 - 2.3e-35 121.3 4.2 2.3e-35 121.3 4.2 1.6 2 0 0 2 2 2 1 Uncharacterized protein family, UPF0114 KdpD PF02702.17 EHT99093.1 - 9.4e-96 319.3 0.1 1.4e-95 318.7 0.1 1.3 1 0 0 1 1 1 1 Osmosensitive K+ channel His kinase sensor domain DUF4118 PF13493.6 EHT99093.1 - 3.9e-27 94.1 11.2 8.4e-27 93.1 11.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4118) HATPase_c PF02518.26 EHT99093.1 - 1.9e-24 86.3 0.0 4.2e-24 85.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EHT99093.1 - 1.3e-09 37.9 2.7 1.5e-09 37.8 0.7 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.6 EHT99093.1 - 8.5e-08 32.6 0.0 2.3e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 GAF domain Usp PF00582.26 EHT99093.1 - 1.5e-05 25.6 0.3 0.00011 22.8 0.3 2.4 1 1 0 1 1 1 1 Universal stress protein family DUF2478 PF10649.9 EHT99093.1 - 0.013 15.1 1.0 1.6 8.4 0.0 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF2478) MASE1 PF05231.14 EHT99093.1 - 0.025 13.7 5.0 0.041 13.0 5.0 1.2 1 0 0 1 1 1 0 MASE1 KdpC PF02669.15 EHT99094.1 - 3e-70 235.8 0.0 3.3e-70 235.6 0.0 1.0 1 0 0 1 1 1 1 K+-transporting ATPase, c chain Hydrolase PF00702.26 EHT99095.1 - 1.1e-34 120.6 3.6 1.9e-34 119.8 3.6 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EHT99095.1 - 1e-29 103.3 0.6 1e-29 103.3 0.6 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EHT99095.1 - 2.1e-05 24.4 0.7 0.00017 21.4 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EHT99095.1 - 0.00022 21.7 0.7 0.0012 19.3 0.2 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase KdpA PF03814.15 EHT99096.1 - 1.3e-239 796.0 36.7 1.5e-239 795.8 36.7 1.0 1 0 0 1 1 1 1 Potassium-transporting ATPase A subunit DUF3391 PF11871.8 EHT99097.1 - 7.9e-18 65.3 0.1 1.3e-17 64.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3391) HD_5 PF13487.6 EHT99097.1 - 7.2e-15 55.0 0.0 1.2e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 HD domain HD PF01966.22 EHT99097.1 - 9.4e-14 51.7 0.4 1.5e-13 51.0 0.4 1.3 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 EHT99097.1 - 0.0095 15.4 0.4 0.021 14.3 0.4 1.6 1 1 0 1 1 1 1 HDOD domain Acetyltransf_1 PF00583.25 EHT99098.1 - 2.3e-19 69.7 0.0 2.8e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 EHT99098.1 - 5.3e-13 49.8 0.0 6.3e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EHT99098.1 - 1.3e-11 44.8 0.0 1.9e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EHT99098.1 - 1.9e-11 44.0 0.0 2.6e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EHT99098.1 - 7.2e-09 36.0 0.0 8.5e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EHT99098.1 - 1.8e-06 27.7 0.0 4.6e-06 26.4 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EHT99098.1 - 2.4e-05 24.4 0.0 4.7e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 EHT99098.1 - 0.00012 21.9 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_6 PF13480.7 EHT99098.1 - 0.019 15.1 0.0 0.029 14.5 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain ABC_tran PF00005.27 EHT99099.1 - 4.5e-34 117.9 0.1 1.1e-33 116.6 0.1 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EHT99099.1 - 2.5e-13 50.3 11.2 3.7e-13 49.8 11.2 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EHT99099.1 - 8.1e-08 32.0 0.0 1.7e-06 27.6 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EHT99099.1 - 0.00016 22.1 0.9 0.00043 20.7 0.5 2.0 2 1 0 2 2 1 1 AAA ATPase domain NTPase_1 PF03266.15 EHT99099.1 - 0.00071 19.5 0.4 0.21 11.5 0.4 2.3 1 1 0 1 1 1 1 NTPase AAA_22 PF13401.6 EHT99099.1 - 0.00086 19.6 0.3 0.026 14.8 0.2 3.0 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EHT99099.1 - 0.00089 19.2 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 EHT99099.1 - 0.0035 17.9 0.0 0.0073 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EHT99099.1 - 0.0044 16.7 0.8 0.0093 15.7 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EHT99099.1 - 0.006 16.7 0.1 0.019 15.1 0.1 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.6 EHT99099.1 - 0.014 15.1 0.0 0.033 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EHT99099.1 - 0.019 14.9 0.1 0.054 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 EHT99099.1 - 0.02 15.3 1.3 0.63 10.5 0.3 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 EHT99099.1 - 0.042 13.9 0.2 0.12 12.4 0.2 1.8 1 1 0 1 1 1 0 Helicase HerA, central domain AAA_28 PF13521.6 EHT99099.1 - 0.065 13.5 0.0 0.4 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 EHT99099.1 - 0.078 12.8 1.1 0.25 11.1 0.2 2.0 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 EHT99099.1 - 0.12 12.1 0.1 0.53 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EHT99099.1 - 0.19 11.9 0.7 0.57 10.3 0.1 2.1 2 1 0 2 2 1 0 AAA domain FemAB_like PF04339.12 EHT99100.1 - 2.6e-146 487.5 1.3 2.9e-146 487.4 1.3 1.0 1 0 0 1 1 1 1 Peptidogalycan biosysnthesis/recognition Acetyltransf_6 PF13480.7 EHT99100.1 - 4.7e-13 49.5 6.7 6.6e-13 49.0 2.7 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Rav1p_C PF12234.8 EHT99100.1 - 0.085 11.2 0.2 0.13 10.7 0.2 1.1 1 0 0 1 1 1 0 RAVE protein 1 C terminal CRCB PF02537.15 EHT99101.1 - 1.7e-23 82.7 8.1 2.1e-23 82.4 8.1 1.1 1 0 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) IU_nuc_hydro PF01156.19 EHT99102.1 - 3.7e-78 263.2 0.0 4.4e-78 262.9 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase ADH_N PF08240.12 EHT99103.1 - 7.4e-31 106.3 2.1 8.6e-31 106.0 1.1 1.7 2 0 0 2 2 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EHT99103.1 - 3.6e-19 69.0 0.1 6.2e-19 68.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EHT99103.1 - 6.4e-11 42.1 0.1 9.3e-11 41.6 0.1 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 EHT99103.1 - 1.5e-05 24.4 1.2 2.4e-05 23.8 1.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 EHT99103.1 - 6.5e-05 22.3 0.5 0.0027 17.0 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N_2 PF13602.6 EHT99103.1 - 7.7e-05 23.8 0.1 0.00018 22.5 0.1 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 3HCDH_N PF02737.18 EHT99103.1 - 0.00024 21.0 0.4 0.00054 19.9 0.4 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EHT99103.1 - 0.0011 18.4 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 EHT99103.1 - 0.0028 17.0 0.4 0.016 14.5 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EHT99103.1 - 0.0043 16.3 0.4 0.0071 15.6 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EHT99103.1 - 0.0047 15.7 0.9 0.0067 15.2 0.9 1.2 1 0 0 1 1 1 1 HI0933-like protein UDPG_MGDP_dh_N PF03721.14 EHT99103.1 - 0.0099 15.5 0.1 0.041 13.5 0.1 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 EHT99103.1 - 0.01 16.4 0.2 0.021 15.4 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 EHT99103.1 - 0.012 15.8 0.1 0.028 14.7 0.1 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GIDA PF01134.22 EHT99103.1 - 0.016 14.3 1.2 0.025 13.7 1.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 EHT99103.1 - 0.019 14.3 7.2 0.025 13.9 4.5 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 EHT99103.1 - 0.022 15.2 0.1 0.041 14.3 0.1 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_8 PF13450.6 EHT99103.1 - 0.024 14.9 1.0 0.054 13.7 1.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain adh_short PF00106.25 EHT99103.1 - 0.033 13.6 1.0 0.077 12.4 0.2 2.0 2 0 0 2 2 2 0 short chain dehydrogenase DAO PF01266.24 EHT99103.1 - 0.035 13.7 0.6 0.068 12.7 0.6 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EHT99103.1 - 0.045 12.8 4.3 0.048 12.7 3.3 1.4 1 1 0 1 1 1 0 FAD binding domain XdhC_C PF13478.6 EHT99103.1 - 0.046 14.2 0.1 0.093 13.2 0.1 1.7 1 1 0 1 1 1 0 XdhC Rossmann domain Shikimate_DH PF01488.20 EHT99103.1 - 0.072 13.2 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_trans_4_5 PF16994.5 EHT99103.1 - 0.09 12.4 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl-transferase family 4 Thi4 PF01946.17 EHT99103.1 - 0.11 11.8 1.0 0.2 10.9 1.0 1.4 1 0 0 1 1 1 0 Thi4 family AdoHcyase_NAD PF00670.21 EHT99103.1 - 0.15 12.1 0.6 0.27 11.3 0.6 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GntR PF00392.21 EHT99104.1 - 1e-13 50.7 0.0 1.5e-07 30.9 0.0 2.5 2 0 0 2 2 2 2 Bacterial regulatory proteins, gntR family FCD PF07729.12 EHT99104.1 - 2.1e-11 44.3 7.7 2.1e-11 44.3 7.7 1.6 2 0 0 2 2 2 1 FCD domain HTH_Crp_2 PF13545.6 EHT99104.1 - 1.5e-05 24.9 0.0 0.00047 20.1 0.0 2.7 3 0 0 3 3 3 1 Crp-like helix-turn-helix domain HTH_11 PF08279.12 EHT99104.1 - 0.00022 21.1 0.0 0.025 14.5 0.0 2.7 2 0 0 2 2 2 1 HTH domain HTH_DeoR PF08220.12 EHT99104.1 - 0.00048 19.8 0.0 0.0025 17.5 0.0 2.3 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain Rrf2 PF02082.20 EHT99104.1 - 0.0022 18.3 0.1 0.25 11.7 0.1 2.6 2 0 0 2 2 2 1 Transcriptional regulator DUF4423 PF14394.6 EHT99104.1 - 0.0068 16.1 0.0 0.56 9.9 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4423) TrmB PF01978.19 EHT99104.1 - 0.014 15.2 0.0 0.047 13.6 0.0 1.8 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 EHT99104.1 - 0.035 13.9 0.1 0.34 10.7 0.1 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain Phage_rep_O PF04492.13 EHT99104.1 - 0.062 13.9 0.0 5.8 7.6 0.0 2.6 2 0 0 2 2 2 0 Bacteriophage replication protein O Penicillinase_R PF03965.16 EHT99104.1 - 0.081 13.3 0.0 0.31 11.4 0.0 2.0 1 0 0 1 1 1 0 Penicillinase repressor HTH_36 PF13730.6 EHT99104.1 - 0.086 12.8 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Fe_dep_repress PF01325.19 EHT99104.1 - 0.14 12.3 0.0 2.6 8.3 0.0 2.3 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain AbiEi_4 PF13338.6 EHT99104.1 - 0.15 12.3 0.0 12 6.1 0.0 2.8 2 1 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin MFS_1 PF07690.16 EHT99105.1 - 9.5e-55 185.9 41.3 1e-53 182.6 34.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EHT99105.1 - 0.0004 18.8 14.4 0.026 12.8 0.6 3.7 2 2 2 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family MFS_4 PF06779.14 EHT99105.1 - 0.02 14.2 22.8 0.046 13.0 4.0 3.2 2 1 1 3 3 3 0 Uncharacterised MFS-type transporter YbfB FAA_hydrolase PF01557.18 EHT99107.1 - 8.2e-57 192.4 0.0 1e-56 192.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Mntp PF02659.15 EHT99108.1 - 3.3e-52 176.3 18.1 9.8e-52 174.8 11.2 2.0 2 0 0 2 2 2 2 Putative manganese efflux pump HemN_C PF06969.16 EHT99108.1 - 0.017 15.1 0.2 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 HemN C-terminal domain DUF2953 PF11167.8 EHT99108.1 - 0.4 10.8 2.7 0.52 10.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) DUF1158 PF06643.11 EHT99109.1 - 4.7e-41 139.2 6.7 5.2e-41 139.0 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1158) Mqo PF06039.15 EHT99110.1 - 9.3e-233 773.1 0.0 1.1e-232 772.9 0.0 1.0 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) XFP_N PF09364.10 EHT99111.1 - 2.3e-180 599.1 0.0 3e-180 598.8 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain PhzC-PhzF PF02567.16 EHT99111.1 - 1.2e-27 97.2 0.0 1.6e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein adh_short_C2 PF13561.6 EHT99112.1 - 1.3e-51 175.4 0.1 1.6e-51 175.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EHT99112.1 - 4.7e-44 150.2 0.0 5.9e-44 149.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EHT99112.1 - 1e-12 48.3 0.0 1.5e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EHT99112.1 - 0.0073 15.8 0.1 0.026 14.0 0.1 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EHT99112.1 - 0.2 11.0 0.0 0.23 10.8 0.0 1.3 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Virul_fac_BrkB PF03631.15 EHT99113.1 - 1e-47 163.0 15.2 1.3e-47 162.6 15.2 1.1 1 0 0 1 1 1 1 Virulence factor BrkB Abhydrolase_9_N PF15420.6 EHT99113.1 - 3.2 7.7 9.3 2.7 7.9 3.2 2.6 1 1 2 3 3 3 0 Alpha/beta-hydrolase family N-terminus Sugar_tr PF00083.24 EHT99114.1 - 5.2e-36 124.5 32.3 5.6e-25 88.1 6.8 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EHT99114.1 - 2e-30 105.9 58.5 7.1e-17 61.4 26.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EHT99114.1 - 0.0013 17.4 17.9 0.0013 17.4 17.9 3.1 2 1 1 3 3 3 3 MFS/sugar transport protein LysR_substrate PF03466.20 EHT99115.1 - 5.4e-05 22.6 0.0 5.6e-05 22.6 0.0 1.0 1 0 0 1 1 1 1 LysR substrate binding domain IlvN PF07991.12 EHT99116.1 - 5.2e-58 195.3 0.9 6.6e-58 194.9 0.3 1.5 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 EHT99116.1 - 7.1e-52 175.5 0.3 2.9e-25 89.2 0.0 2.3 2 0 0 2 2 2 2 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.19 EHT99116.1 - 0.00044 19.7 0.0 0.00081 18.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 EHT99116.1 - 0.0095 16.0 0.1 0.019 15.0 0.1 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ApbA PF02558.16 EHT99116.1 - 0.012 15.3 0.1 0.022 14.4 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 EHT99116.1 - 0.015 15.7 0.1 0.054 13.9 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_2 PF03446.15 EHT99116.1 - 0.086 13.0 0.0 0.49 10.6 0.0 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 EHT99116.1 - 0.39 11.0 0.0 0.39 11.0 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain LysR_substrate PF03466.20 EHT99117.1 - 4.9e-36 124.1 3.6 6.9e-36 123.6 3.6 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EHT99117.1 - 1.4e-20 73.0 0.4 2.8e-20 72.0 0.4 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 EHT99117.1 - 2.9e-05 23.8 0.3 6.5e-05 22.7 0.3 1.6 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_24 PF13412.6 EHT99117.1 - 0.016 14.8 0.0 0.046 13.3 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR PF01047.22 EHT99117.1 - 0.017 15.0 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 MarR family SBP_bac_11 PF13531.6 EHT99117.1 - 0.024 14.4 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein MarR_2 PF12802.7 EHT99117.1 - 0.025 14.4 0.2 0.083 12.8 0.0 1.9 2 0 0 2 2 2 0 MarR family HTH_23 PF13384.6 EHT99117.1 - 0.08 12.8 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_38 PF13936.6 EHT99117.1 - 0.087 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Fe_dep_repress PF01325.19 EHT99117.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_28 PF13518.6 EHT99117.1 - 0.12 12.5 0.0 0.45 10.7 0.0 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_20 PF12840.7 EHT99117.1 - 0.47 10.6 3.5 1.4 9.0 0.1 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain PALP PF00291.25 EHT99118.1 - 2.3e-79 266.9 4.6 2.9e-79 266.5 4.6 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 EHT99118.1 - 4.3e-59 196.3 0.0 5e-30 103.1 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase TraT PF05818.12 EHT99118.1 - 0.0088 15.8 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 Enterobacterial TraT complement resistance protein ILVD_EDD PF00920.21 EHT99119.1 - 1.4e-216 720.1 3.4 1.6e-216 719.9 3.4 1.0 1 0 0 1 1 1 1 Dehydratase family Ribosomal_S27 PF01599.19 EHT99119.1 - 0.77 10.0 3.6 34 4.7 0.5 3.1 3 0 0 3 3 3 0 Ribosomal protein S27a Aminotran_4 PF01063.19 EHT99120.1 - 3.7e-48 164.3 0.0 4.3e-48 164.1 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV ACT_5 PF13710.6 EHT99121.1 - 1.3e-27 95.4 0.5 1.6e-27 95.1 0.5 1.1 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 EHT99121.1 - 1.3e-05 25.7 0.4 1.7e-05 25.3 0.4 1.1 1 0 0 1 1 1 1 ACT domain TPP_enzyme_N PF02776.18 EHT99122.1 - 2.8e-57 193.1 4.6 3.9e-57 192.6 0.3 2.9 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EHT99122.1 - 2.8e-48 163.6 0.2 1.2e-46 158.3 0.0 2.8 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EHT99122.1 - 1e-42 145.1 0.2 2.2e-42 144.0 0.2 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 EHT99122.1 - 0.0047 16.7 2.0 0.0078 16.0 2.0 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg CO_dh PF02552.16 EHT99122.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit XFP_N PF09364.10 EHT99122.1 - 0.15 10.8 0.1 0.27 10.0 0.1 1.3 1 0 0 1 1 1 0 XFP N-terminal domain Mg_chelatase PF01078.21 EHT99123.1 - 8.6e-91 302.9 0.0 1.4e-90 302.2 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ChlI PF13541.6 EHT99123.1 - 4.7e-42 142.7 0.0 9.2e-42 141.7 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Mg_chelatase_C PF13335.6 EHT99123.1 - 3.2e-28 98.2 2.3 6.7e-28 97.2 2.3 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI C-terminal MCM PF00493.23 EHT99123.1 - 3e-12 46.1 0.0 3e-10 39.6 0.0 2.2 2 0 0 2 2 2 1 MCM P-loop domain AAA_5 PF07728.14 EHT99123.1 - 1.6e-10 41.1 0.0 4.3e-10 39.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EHT99123.1 - 7.5e-06 25.8 0.0 0.02 14.6 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_32 PF13654.6 EHT99123.1 - 0.00029 19.8 0.0 0.027 13.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EHT99123.1 - 0.0012 19.3 0.2 0.011 16.1 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 EHT99123.1 - 0.0014 19.0 0.4 0.0074 16.7 0.4 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EHT99123.1 - 0.0033 17.2 0.0 0.38 10.5 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EHT99123.1 - 0.013 15.8 0.0 0.035 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EHT99123.1 - 0.018 14.8 0.1 0.041 13.6 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 EHT99123.1 - 0.025 14.7 0.1 0.11 12.7 0.0 2.1 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.6 EHT99123.1 - 0.034 13.9 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EHT99123.1 - 0.034 13.7 0.0 0.088 12.3 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_lid_2 PF17863.1 EHT99123.1 - 0.055 13.3 0.1 0.32 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA lid domain Sigma54_activ_2 PF14532.6 EHT99123.1 - 0.063 13.4 0.0 11 6.1 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain TIP49 PF06068.13 EHT99123.1 - 0.066 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_19 PF13245.6 EHT99123.1 - 0.073 13.4 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_lid_8 PF17868.1 EHT99123.1 - 0.086 12.7 0.2 2.3 8.1 0.1 2.4 2 0 0 2 2 2 0 AAA lid domain AAA_25 PF13481.6 EHT99123.1 - 0.093 12.3 0.1 0.27 10.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.14 EHT99123.1 - 0.19 10.8 0.0 0.35 10.0 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase DDE_Tnp_1 PF01609.21 EHT99124.1 - 4.6e-20 72.2 0.0 1.1e-19 70.9 0.0 1.5 1 1 0 1 1 1 1 Transposase DDE domain DUF413 PF04219.12 EHT99125.1 - 1.1e-37 127.9 0.1 1.3e-37 127.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF HTH_1 PF00126.27 EHT99126.1 - 1.5e-20 72.9 1.4 3e-20 71.9 1.4 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 EHT99126.1 - 1.3e-16 60.6 0.6 2.4e-16 59.7 0.6 1.4 1 1 0 1 1 1 1 LysR substrate binding domain HTH_30 PF13556.6 EHT99126.1 - 0.039 13.8 1.0 0.1 12.4 1.0 1.8 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain TnpB_IS66 PF05717.13 EHT99127.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHT99128.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT99128.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT99128.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT99128.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix Ribosomal_L9_C PF03948.14 EHT99130.1 - 8.1e-25 87.1 0.7 1.3e-24 86.5 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L9, C-terminal domain Ribosomal_L9_N PF01281.19 EHT99130.1 - 3.5e-22 77.7 0.4 6.5e-22 76.8 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_S18 PF01084.20 EHT99131.1 - 7.5e-25 86.9 0.5 9.8e-25 86.5 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S18 SSB PF00436.25 EHT99132.1 - 1.5e-13 50.6 0.0 1.7e-13 50.5 0.0 1.0 1 0 0 1 1 1 1 Single-strand binding protein family Ribosomal_S6 PF01250.17 EHT99133.1 - 5.5e-28 97.1 0.0 7.5e-28 96.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 DUF2313 PF10076.9 EHT99133.1 - 0.054 13.4 0.0 0.48 10.3 0.0 2.0 1 1 1 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2313) Peptidase_S9 PF00326.21 EHT99134.1 - 6.8e-14 51.9 0.1 9.3e-14 51.4 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EHT99134.1 - 3.6e-13 49.3 1.7 5.7e-09 35.6 1.1 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EHT99134.1 - 2.1e-07 30.9 0.6 1.1e-05 25.2 0.4 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 EHT99134.1 - 8e-07 28.8 0.0 3.9e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.20 EHT99134.1 - 5.8e-06 26.1 0.0 7.5e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 EHT99134.1 - 1.2e-05 26.0 1.8 2.5e-05 25.0 1.7 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EHT99134.1 - 1.6e-05 24.8 0.0 0.012 15.4 0.0 2.8 1 1 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.7 EHT99134.1 - 2e-05 24.4 0.5 0.14 12.0 0.0 3.0 2 1 1 3 3 3 2 Alpha/beta hydrolase family PAF-AH_p_II PF03403.13 EHT99134.1 - 0.00064 18.3 0.5 0.0074 14.8 0.0 2.0 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II BAAT_C PF08840.11 EHT99134.1 - 0.00083 19.3 0.2 0.0045 16.9 0.2 1.9 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Chlorophyllase2 PF12740.7 EHT99134.1 - 0.0021 17.0 0.0 0.0029 16.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Esterase_phd PF10503.9 EHT99134.1 - 0.0032 17.0 1.3 0.014 14.9 1.3 1.9 1 1 0 1 1 1 1 Esterase PHB depolymerase Chlorophyllase PF07224.11 EHT99134.1 - 0.026 13.6 0.3 0.07 12.1 0.3 1.5 1 1 0 1 1 1 0 Chlorophyllase AXE1 PF05448.12 EHT99134.1 - 0.045 12.4 0.6 3.8 6.1 0.2 2.1 1 1 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF2920 PF11144.8 EHT99134.1 - 0.051 12.8 0.0 0.25 10.5 0.0 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF2920) FSH1 PF03959.13 EHT99134.1 - 0.066 12.9 0.0 0.36 10.4 0.0 2.0 1 1 0 1 1 1 0 Serine hydrolase (FSH1) LIP PF03583.14 EHT99134.1 - 0.13 11.6 0.0 0.61 9.4 0.0 1.9 2 1 0 2 2 2 0 Secretory lipase Cache_3-Cache_2 PF17201.4 EHT99135.1 - 2.5e-70 237.0 0.4 2.5e-70 237.0 0.4 2.8 3 0 0 3 3 3 1 Cache 3/Cache 2 fusion domain MCPsignal PF00015.21 EHT99135.1 - 1.2e-46 158.7 40.5 3.9e-45 153.7 22.6 3.2 2 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain sCache_3_3 PF17202.4 EHT99135.1 - 7.3e-28 97.1 1.0 3.4e-27 95.0 0.4 2.5 2 0 0 2 2 2 1 Single cache domain 3 sCache_3_2 PF17203.4 EHT99135.1 - 2.6e-11 43.8 0.1 2.6e-11 43.8 0.1 2.8 3 1 0 3 3 3 1 Single cache domain 3 HAMP PF00672.25 EHT99135.1 - 1.2e-09 38.4 1.6 7.6e-08 32.6 0.1 4.0 3 0 0 3 3 2 1 HAMP domain dCache_1 PF02743.18 EHT99135.1 - 7.3e-09 35.8 0.3 7.3e-09 35.8 0.3 3.6 3 0 0 3 3 3 1 Cache domain PLU-1 PF08429.11 EHT99135.1 - 0.0004 19.7 1.7 0.00066 18.9 1.7 1.3 1 0 0 1 1 1 1 PLU-1-like protein DUF848 PF05852.11 EHT99135.1 - 0.05 13.7 1.5 0.3 11.2 0.2 2.5 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Seryl_tRNA_N PF02403.22 EHT99135.1 - 0.17 12.1 5.9 22 5.3 0.0 3.7 2 2 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.12 EHT99135.1 - 0.19 11.8 13.7 0.28 11.2 0.3 3.3 3 1 1 4 4 3 0 Protein of unknown function (DUF1664) Spectrin PF00435.21 EHT99135.1 - 0.52 10.8 8.2 6.1 7.4 0.2 3.7 3 0 0 3 3 3 0 Spectrin repeat COG2 PF06148.11 EHT99135.1 - 0.64 10.1 7.4 0.61 10.2 0.2 3.8 3 2 1 4 4 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Laminin_II PF06009.12 EHT99135.1 - 0.81 9.7 16.6 0.43 10.6 4.0 3.7 3 1 0 3 3 3 0 Laminin Domain II DUF2887 PF11103.8 EHT99135.1 - 1.1 9.2 5.3 0.39 10.7 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2887) DUF1465 PF07323.12 EHT99135.1 - 1.2 8.9 7.9 0.14 12.0 2.5 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1465) ISG65-75 PF11727.8 EHT99135.1 - 1.8 7.7 8.0 2.9 7.0 0.5 2.2 2 0 0 2 2 2 0 Invariant surface glycoprotein ASL_C PF08328.11 EHT99135.1 - 1.8 8.7 6.8 26 5.0 0.9 3.6 2 2 1 3 3 3 0 Adenylosuccinate lyase C-terminal Fib_alpha PF08702.10 EHT99135.1 - 4.3 7.5 8.9 0.29 11.3 0.7 2.8 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF948 PF06103.11 EHT99135.1 - 5.5 7.3 25.0 0.4 11.0 0.2 5.3 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) APG17 PF04108.12 EHT99135.1 - 6 5.9 14.2 0.76 8.8 0.7 3.1 2 1 1 3 3 3 0 Autophagy protein Apg17 YkyA PF10368.9 EHT99135.1 - 9.2 5.9 6.8 9.9 5.8 0.3 2.9 2 1 0 2 2 2 0 Putative cell-wall binding lipoprotein DUF1471 PF07338.13 EHT99136.1 - 7.6e-17 61.0 0.1 1.2e-16 60.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1471) AidB_N PF18158.1 EHT99137.1 - 2.3e-55 186.8 0.5 8.4e-55 185.0 0.0 2.2 3 0 0 3 3 3 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 EHT99137.1 - 7.9e-29 100.8 1.0 1.3e-28 100.1 1.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EHT99137.1 - 6.1e-13 48.8 0.0 1e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EHT99137.1 - 2.7e-08 34.2 1.7 3.3e-08 33.9 0.1 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain SpoU_methylase PF00588.19 EHT99138.1 - 1.6e-40 138.6 0.0 2.1e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 EHT99138.1 - 2.3e-21 75.9 0.0 1.4e-20 73.3 0.0 2.0 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding RNB PF00773.19 EHT99139.1 - 6.8e-109 364.1 0.0 1.1e-108 363.4 0.0 1.3 1 0 0 1 1 1 1 RNB domain OB_RNB PF08206.11 EHT99139.1 - 3.4e-26 90.7 9.8 1.3e-21 76.0 0.2 4.1 4 0 0 4 4 4 2 Ribonuclease B OB domain CSD2 PF17876.1 EHT99139.1 - 2.9e-22 78.6 0.0 4.9e-21 74.7 0.0 2.5 2 0 0 2 2 2 1 Cold shock domain S1 PF00575.23 EHT99139.1 - 2.2e-16 59.9 0.2 5e-16 58.8 0.2 1.7 1 0 0 1 1 1 1 S1 RNA binding domain HTH_12 PF08461.10 EHT99139.1 - 4.9e-16 58.4 2.4 1.1e-15 57.3 2.4 1.7 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain RNase_II_C_S1 PF18614.1 EHT99139.1 - 0.0031 17.4 0.4 0.037 14.0 0.1 2.9 3 0 0 3 3 3 1 RNase II-type exonuclease C-terminal S1 domain LexA_DNA_bind PF01726.16 EHT99139.1 - 0.026 14.3 0.2 0.085 12.6 0.2 1.9 1 0 0 1 1 1 0 LexA DNA binding domain Rho_RNA_bind PF07497.12 EHT99139.1 - 0.046 13.6 0.0 0.17 11.8 0.0 1.9 1 0 0 1 1 1 0 Rho termination factor, RNA-binding domain TFIIE_beta PF02186.15 EHT99139.1 - 0.23 11.8 0.5 1.3 9.4 0.2 2.4 2 0 0 2 2 2 0 TFIIE beta subunit core domain YqfQ PF14181.6 EHT99139.1 - 0.24 11.6 0.0 0.24 11.6 0.0 2.5 2 1 0 2 2 2 0 YqfQ-like protein Rrf2 PF02082.20 EHT99140.1 - 9.6e-24 83.6 0.0 1.6e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator TrmB PF01978.19 EHT99140.1 - 0.0016 18.3 0.0 0.0057 16.5 0.0 1.9 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_27 PF13463.6 EHT99140.1 - 0.0054 17.2 0.0 0.013 16.0 0.0 1.7 2 0 0 2 2 2 1 Winged helix DNA-binding domain MarR_2 PF12802.7 EHT99140.1 - 0.028 14.3 0.0 0.068 13.1 0.0 1.6 1 0 0 1 1 1 0 MarR family GntR PF00392.21 EHT99140.1 - 0.046 13.4 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family Adenylsucc_synt PF00709.21 EHT99141.1 - 1.4e-177 590.8 0.1 1.7e-177 590.6 0.1 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DUF2065 PF09838.9 EHT99142.1 - 2.8e-18 65.7 8.7 3.2e-18 65.5 8.7 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2065) Band_7 PF01145.25 EHT99143.1 - 9.8e-33 113.6 0.8 1.3e-32 113.3 0.5 1.3 1 1 0 1 1 1 1 SPFH domain / Band 7 family CCP_MauG PF03150.14 EHT99143.1 - 0.0092 16.6 2.2 0.033 14.8 2.5 1.8 2 1 0 2 2 2 1 Di-haem cytochrome c peroxidase Calsequestrin PF01216.17 EHT99143.1 - 0.1 11.6 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Calsequestrin Band_7 PF01145.25 EHT99144.1 - 1.8e-30 106.3 2.3 2.9e-30 105.6 2.3 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family HflK_N PF12221.8 EHT99144.1 - 1.2e-14 54.0 13.2 3.3e-14 52.6 13.2 1.8 1 0 0 1 1 1 1 Bacterial membrane protein N terminal DivIVA PF05103.13 EHT99144.1 - 0.15 12.2 2.1 0.27 11.3 2.1 1.4 1 0 0 1 1 1 0 DivIVA protein CD99L2 PF12301.8 EHT99144.1 - 0.18 12.1 2.7 0.23 11.7 0.7 2.0 2 0 0 2 2 2 0 CD99 antigen like protein 2 GTP-bdg_N PF13167.6 EHT99145.1 - 4.7e-30 104.1 0.0 1.1e-29 102.9 0.0 1.7 1 0 0 1 1 1 1 GTP-binding GTPase N-terminal GTP-bdg_M PF16360.5 EHT99145.1 - 1.6e-28 99.1 12.7 1.6e-28 99.1 11.3 1.8 2 0 0 2 2 1 1 GTP-binding GTPase Middle Region MMR_HSR1 PF01926.23 EHT99145.1 - 1.4e-21 76.6 0.1 4.8e-21 75.0 0.1 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EHT99145.1 - 8e-07 28.7 0.1 1.2e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EHT99145.1 - 1.1e-05 25.5 0.0 0.1 12.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Arf PF00025.21 EHT99145.1 - 0.00016 21.2 0.9 0.00099 18.6 0.9 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EHT99145.1 - 0.0023 17.5 0.0 0.73 9.3 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EHT99145.1 - 0.0071 16.4 0.1 0.034 14.2 0.1 2.0 1 1 0 1 1 1 1 Dynamin family MMR_HSR1_Xtn PF16897.5 EHT99145.1 - 0.011 15.8 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain SRPRB PF09439.10 EHT99145.1 - 0.018 14.5 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 EHT99145.1 - 0.019 15.5 0.0 0.09 13.3 0.0 2.1 2 0 0 2 2 2 0 ABC transporter cobW PF02492.19 EHT99145.1 - 0.024 14.2 3.1 0.4 10.2 0.5 2.4 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TniB PF05621.11 EHT99145.1 - 0.026 13.9 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.6 EHT99145.1 - 0.026 14.2 0.0 0.075 12.8 0.0 1.8 2 0 0 2 2 1 0 P-loop containing region of AAA domain Roc PF08477.13 EHT99145.1 - 0.028 14.7 0.1 0.43 10.8 0.1 2.3 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 EHT99145.1 - 0.034 14.7 0.3 0.086 13.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain G-alpha PF00503.20 EHT99145.1 - 0.042 13.0 0.0 2.5 7.2 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Gtr1_RagA PF04670.12 EHT99145.1 - 0.047 13.0 0.0 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 EHT99145.1 - 0.099 12.4 0.8 0.26 11.0 0.2 1.7 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Hfq PF17209.3 EHT99146.1 - 4.3e-31 106.4 0.1 5.4e-31 106.1 0.1 1.1 1 0 0 1 1 1 1 Hfq protein LSM PF01423.22 EHT99146.1 - 0.0028 17.3 0.0 0.0038 16.9 0.0 1.3 1 0 0 1 1 1 1 LSM domain IPPT PF01715.17 EHT99147.1 - 2.4e-83 279.5 0.0 2.8e-83 279.2 0.0 1.0 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 EHT99147.1 - 2.5e-06 27.1 0.0 5.5e-06 25.9 0.0 1.5 2 0 0 2 2 2 1 Isopentenyl transferase AAA_33 PF13671.6 EHT99147.1 - 4.4e-05 23.7 0.0 0.00017 21.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EHT99147.1 - 0.00065 20.1 0.9 0.0016 18.8 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 EHT99147.1 - 0.0033 16.7 0.0 0.0082 15.4 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin TIP49 PF06068.13 EHT99147.1 - 0.016 14.5 0.0 0.022 14.0 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain Cytidylate_kin PF02224.18 EHT99147.1 - 0.039 13.7 0.0 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 Cytidylate kinase AAA_18 PF13238.6 EHT99147.1 - 0.049 14.2 0.0 0.092 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EHT99147.1 - 0.056 13.7 0.0 0.16 12.2 0.0 1.8 1 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EHT99147.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DNA_mis_repair PF01119.19 EHT99148.1 - 1.8e-38 130.8 0.0 3e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 EHT99148.1 - 2.1e-27 95.7 2.5 4.1e-27 94.7 2.5 1.5 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 EHT99148.1 - 4.6e-13 49.2 0.1 8.2e-13 48.4 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EHT99148.1 - 8.2e-08 32.7 0.0 2.1e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Amidase_3 PF01520.18 EHT99149.1 - 4.8e-45 153.8 0.0 8e-45 153.1 0.0 1.4 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase LysM PF01476.20 EHT99149.1 - 5.1e-28 96.9 0.0 6.9e-13 48.4 0.0 2.6 2 0 0 2 2 2 2 LysM domain AMIN PF11741.8 EHT99149.1 - 3e-08 33.7 0.4 6.6e-08 32.6 0.4 1.6 1 0 0 1 1 1 1 AMIN domain HTH_23 PF13384.6 EHT99149.1 - 0.0067 16.2 0.3 4.4 7.2 0.1 2.6 2 0 0 2 2 2 2 Homeodomain-like domain HTH_28 PF13518.6 EHT99149.1 - 0.043 13.9 0.4 2.4 8.3 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 EHT99149.1 - 0.049 13.2 0.1 7.5 6.2 0.1 3.3 4 0 0 4 4 4 0 Sigma-70, region 4 TsaE PF02367.17 EHT99150.1 - 1.3e-39 135.0 0.0 1.6e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EHT99150.1 - 0.018 15.2 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 EHT99150.1 - 0.088 12.9 0.0 0.1 12.7 0.0 1.2 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 EHT99150.1 - 0.16 11.7 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EHT99150.1 - 0.26 10.6 0.1 0.38 10.1 0.1 1.2 1 0 0 1 1 1 0 KaiC Carb_kinase PF01256.17 EHT99151.1 - 2.1e-71 240.3 2.9 2.1e-71 240.3 2.9 1.5 2 0 0 2 2 2 1 Carbohydrate kinase YjeF_N PF03853.15 EHT99151.1 - 4e-42 144.0 0.1 8.5e-42 142.9 0.1 1.6 1 0 0 1 1 1 1 YjeF-related protein N-terminus HK PF02110.15 EHT99151.1 - 3.1e-05 23.5 1.7 7.3e-05 22.3 1.7 1.7 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.12 EHT99151.1 - 0.0076 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DUF1730 PF08331.10 EHT99152.1 - 2.7e-25 88.1 0.0 7.1e-25 86.7 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1730) Fer4_16 PF13484.6 EHT99152.1 - 1.6e-19 70.6 3.9 3e-19 69.7 3.9 1.5 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 EHT99152.1 - 2.1e-05 24.6 4.7 0.0074 16.4 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EHT99152.1 - 9.1e-05 22.5 2.2 0.0077 16.4 0.3 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 EHT99152.1 - 0.00025 21.6 7.1 0.0017 18.9 7.2 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 EHT99152.1 - 0.015 15.7 2.3 0.37 11.3 1.4 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4 PF00037.27 EHT99152.1 - 0.016 15.0 3.9 0.016 15.0 3.9 2.9 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_6 PF12837.7 EHT99152.1 - 0.016 15.3 14.3 0.29 11.3 5.4 2.9 2 2 0 2 2 2 0 4Fe-4S binding domain Fer4_21 PF14697.6 EHT99152.1 - 0.018 15.1 6.6 1 9.5 2.7 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain DUF3145 PF11343.8 EHT99152.1 - 0.07 12.7 0.7 0.16 11.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3145) Fer4_4 PF12800.7 EHT99152.1 - 2.6 8.8 8.5 37 5.2 0.1 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 EHT99152.1 - 4.8 8.3 15.4 2.2 9.4 4.7 2.7 3 0 0 3 3 2 0 4Fe-4S binding domain RNase_T PF00929.24 EHT99153.1 - 1.1e-37 130.1 0.0 1.3e-37 129.9 0.0 1.0 1 0 0 1 1 1 1 Exonuclease RsgA_GTPase PF03193.16 EHT99154.1 - 1.3e-53 181.4 0.0 1.6e-53 181.0 0.0 1.1 1 0 0 1 1 1 1 RsgA GTPase cobW PF02492.19 EHT99154.1 - 1.7e-06 27.7 0.1 0.00067 19.3 0.0 2.2 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 EHT99154.1 - 1.5e-05 25.1 0.0 3.9e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EHT99154.1 - 5.5e-05 22.7 0.7 0.19 11.3 0.2 2.4 2 1 0 2 2 2 2 Ferrous iron transport protein B ABC_tran PF00005.27 EHT99154.1 - 0.00017 22.1 0.4 0.0031 18.0 0.0 2.3 2 0 0 2 2 2 1 ABC transporter Dynamin_N PF00350.23 EHT99154.1 - 0.0054 16.8 0.1 0.015 15.4 0.1 1.6 1 1 0 1 1 1 1 Dynamin family AAA_29 PF13555.6 EHT99154.1 - 0.015 15.0 0.1 0.035 13.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ras PF00071.22 EHT99154.1 - 0.02 14.5 0.1 5.8 6.5 0.0 2.2 1 1 1 2 2 2 0 Ras family MMR_HSR1_Xtn PF16897.5 EHT99154.1 - 0.025 14.6 0.1 0.048 13.7 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain GTP_EFTU PF00009.27 EHT99154.1 - 0.03 13.9 0.3 0.36 10.3 0.1 2.3 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EHT99154.1 - 0.038 14.4 0.1 0.098 13.0 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain IIGP PF05049.13 EHT99154.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.6 EHT99154.1 - 0.11 12.8 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EHT99154.1 - 0.2 11.3 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain PS_Dcarbxylase PF02666.15 EHT99155.1 - 5e-59 199.2 0.0 6e-59 199.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase DNA_binding_2 PF13724.6 EHT99155.1 - 0.23 11.9 0.5 6.6 7.2 0.1 2.4 2 0 0 2 2 2 0 DNA-binding domain MscS_TM PF12794.7 EHT99156.1 - 4.1e-113 377.7 19.0 2.4e-112 375.2 19.0 2.4 1 0 0 1 1 1 1 Mechanosensitive ion channel inner membrane domain 1 MscS_porin PF12795.7 EHT99156.1 - 1.6e-57 194.8 55.3 1.6e-57 194.8 55.3 3.3 3 1 0 4 4 4 1 Mechanosensitive ion channel porin domain MS_channel PF00924.18 EHT99156.1 - 1.9e-49 168.0 0.1 5.3e-49 166.6 0.1 1.9 1 0 0 1 1 1 1 Mechanosensitive ion channel Ldh_1_C PF02866.18 EHT99157.1 - 1.3e-51 174.9 0.0 1.8e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EHT99157.1 - 4.6e-46 156.4 0.9 6.5e-46 155.9 0.9 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 EHT99157.1 - 0.099 13.1 1.0 0.24 11.9 0.1 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 EHT99157.1 - 0.26 11.1 2.8 0.91 9.4 2.8 1.9 1 1 0 1 1 1 0 NAD(P)H-binding Arg_repressor PF01316.21 EHT99158.1 - 3.8e-25 87.4 0.0 5.7e-25 86.9 0.0 1.3 1 0 0 1 1 1 1 Arginine repressor, DNA binding domain Arg_repressor_C PF02863.18 EHT99158.1 - 6.9e-23 80.3 0.2 1.1e-22 79.7 0.2 1.3 1 0 0 1 1 1 1 Arginine repressor, C-terminal domain DUF4911 PF16256.5 EHT99158.1 - 0.027 14.4 0.0 0.077 13.0 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4911) DUF1471 PF07338.13 EHT99159.1 - 1.3e-22 79.5 0.4 2e-22 78.9 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1471) Htr2 PF17909.1 EHT99159.1 - 0.27 11.6 5.1 0.42 10.9 5.1 1.3 1 0 0 1 1 1 0 Htr2 transmembrane domain DUF1471 PF07338.13 EHT99160.1 - 3.9e-15 55.6 0.0 5.8e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1471) DUF4148 PF13663.6 EHT99160.1 - 0.049 13.8 1.3 0.049 13.8 1.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) DUF1471 PF07338.13 EHT99161.1 - 6.7e-21 74.0 0.5 1.1e-20 73.4 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1471) RecX PF02631.16 EHT99162.1 - 0.13 12.7 0.8 9.1 6.8 0.3 2.0 1 1 0 2 2 2 0 RecX family Transposase_31 PF04754.12 EHT99163.1 - 0.0053 16.4 0.1 0.0053 16.4 0.1 1.0 1 0 0 1 1 1 1 Putative transposase, YhgA-like FUSC PF04632.12 EHT99164.1 - 1.5e-48 165.9 19.2 1.9e-48 165.5 19.2 1.0 1 0 0 1 1 1 1 Fusaric acid resistance protein family FUSC_2 PF13515.6 EHT99164.1 - 3.1e-11 43.5 16.7 4.4e-11 43.0 16.7 1.2 1 0 0 1 1 1 1 Fusaric acid resistance protein-like ALMT PF11744.8 EHT99164.1 - 0.0068 15.3 9.6 0.0086 14.9 9.6 1.1 1 0 0 1 1 1 1 Aluminium activated malate transporter DUF4203 PF13886.6 EHT99164.1 - 3.6 7.2 23.5 0.44 10.2 0.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4203) Biotin_lipoyl_2 PF13533.6 EHT99165.1 - 8.4e-20 70.4 0.7 9.1e-16 57.4 0.6 2.5 2 0 0 2 2 2 2 Biotin-lipoyl like HlyD_D23 PF16576.5 EHT99165.1 - 1.5e-15 57.0 1.6 3.3e-15 55.9 0.6 2.0 2 1 0 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 EHT99165.1 - 4.9e-12 46.5 0.3 3.1e-08 34.3 0.0 3.1 2 1 0 2 2 2 2 HlyD family secretion protein HlyD PF00529.20 EHT99165.1 - 2.2e-06 27.4 0.0 3.9e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl PF00364.22 EHT99165.1 - 0.02 14.7 0.1 6.4 6.7 0.1 2.4 2 0 0 2 2 2 0 Biotin-requiring enzyme APG6_N PF17675.1 EHT99165.1 - 0.31 11.6 2.5 0.47 11.0 2.5 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Flp1_like PF16982.5 EHT99165.1 - 2.4 7.6 5.5 6.7 6.2 5.5 1.7 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain DUF1656 PF07869.12 EHT99166.1 - 2.1e-19 69.2 7.9 2.6e-19 69.0 7.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1656) LysR_substrate PF03466.20 EHT99167.1 - 1.3e-37 129.3 0.0 2.4e-37 128.3 0.0 1.4 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 EHT99167.1 - 5.6e-20 71.1 0.5 1.1e-19 70.1 0.5 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_Tnp_ISL3 PF13542.6 EHT99167.1 - 0.0015 17.9 0.1 0.0034 16.7 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_30 PF13556.6 EHT99167.1 - 0.0046 16.7 0.2 0.013 15.2 0.1 1.8 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain MarR_2 PF12802.7 EHT99167.1 - 0.0094 15.8 0.2 0.022 14.6 0.2 1.5 1 0 0 1 1 1 1 MarR family GST_N_4 PF17172.4 EHT99167.1 - 0.021 15.6 0.0 0.061 14.1 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain HTH_23 PF13384.6 EHT99167.1 - 0.1 12.4 0.1 0.48 10.3 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_24 PF13412.6 EHT99167.1 - 0.14 11.7 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding PmbA_TldD PF01523.16 EHT99168.1 - 7.1e-68 229.5 0.3 1e-67 228.9 0.3 1.3 1 0 0 1 1 1 1 Putative modulator of DNA gyrase TetR_C_35 PF18556.1 EHT99168.1 - 0.25 11.5 2.4 20 5.4 0.0 2.9 3 0 0 3 3 3 0 Bacterial Tetracyclin repressor, C-terminal domain DUF3971 PF13116.6 EHT99169.1 - 3.4e-95 318.9 2.9 4.2e-94 315.4 0.8 3.2 3 0 0 3 3 3 1 Protein of unknown function AsmA_2 PF13502.6 EHT99169.1 - 1.1e-67 228.0 9.3 1.1e-64 218.1 1.2 4.9 5 0 0 5 5 5 3 AsmA-like C-terminal region RNase_E_G PF10150.9 EHT99170.1 - 2.7e-99 332.0 0.1 4.7e-99 331.2 0.1 1.4 1 0 0 1 1 1 1 Ribonuclease E/G family S1 PF00575.23 EHT99170.1 - 8.5e-06 26.0 0.9 2.7e-05 24.4 0.1 2.1 2 0 0 2 2 2 1 S1 RNA binding domain Maf PF02545.14 EHT99171.1 - 1.1e-58 197.7 0.0 1.3e-58 197.6 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein MreD PF04093.12 EHT99172.1 - 7.8e-43 146.3 21.8 8.8e-43 146.1 21.8 1.0 1 0 0 1 1 1 1 rod shape-determining protein MreD MreC PF04085.14 EHT99173.1 - 1.2e-37 129.1 0.1 1.8e-37 128.6 0.1 1.3 1 0 0 1 1 1 1 rod shape-determining protein MreC MreB_Mbl PF06723.13 EHT99174.1 - 1.3e-150 500.8 3.4 1.6e-150 500.5 3.4 1.0 1 0 0 1 1 1 1 MreB/Mbl protein HSP70 PF00012.20 EHT99174.1 - 2.3e-13 49.2 0.2 4.6e-13 48.2 0.1 1.6 1 1 1 2 2 2 1 Hsp70 protein FtsA PF14450.6 EHT99174.1 - 2.4e-11 43.9 0.2 8.2e-11 42.2 0.0 1.9 2 0 0 2 2 2 1 Cell division protein FtsA Actin PF00022.19 EHT99174.1 - 3.6e-10 39.0 0.0 2.1e-06 26.6 0.0 2.2 1 1 0 2 2 2 2 Actin PilM_2 PF11104.8 EHT99174.1 - 1.2e-07 31.2 0.0 0.0025 16.9 0.0 2.4 2 0 0 2 2 2 2 Type IV pilus assembly protein PilM; Ppx-GppA PF02541.16 EHT99174.1 - 0.00063 19.3 0.1 0.0011 18.5 0.1 1.4 1 0 0 1 1 1 1 Ppx/GppA phosphatase family EutA PF06277.11 EHT99174.1 - 0.0026 16.7 0.2 0.0041 16.0 0.2 1.3 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutA DDR PF08841.10 EHT99174.1 - 0.0042 16.1 0.4 0.012 14.7 0.1 1.8 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain EAL PF00563.20 EHT99175.1 - 5.4e-37 127.6 0.0 1.1e-36 126.6 0.0 1.5 1 0 0 1 1 1 1 EAL domain GAPES4 PF17157.4 EHT99175.1 - 2.9e-25 88.5 0.8 8.8e-25 87.0 0.8 1.9 1 0 0 1 1 1 1 Gammaproteobacterial periplasmic sensor domain GGDEF PF00990.21 EHT99175.1 - 2e-21 76.4 0.0 3.1e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain MLANA PF14991.6 EHT99175.1 - 0.22 11.8 0.9 3 8.1 0.0 2.5 3 0 0 3 3 3 0 Protein melan-A Oxidored_molyb PF00174.19 EHT99176.1 - 1.8e-29 102.6 0.0 4.6e-29 101.2 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain TAT_signal PF10518.9 EHT99176.1 - 0.0021 17.8 1.2 0.0033 17.2 1.2 1.3 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence Ferric_reduct PF01794.19 EHT99177.1 - 8.3e-14 51.8 11.9 8.3e-14 51.8 11.9 2.2 2 1 0 2 2 2 1 Ferric reductase like transmembrane component DUF5058 PF16481.5 EHT99177.1 - 0.0019 17.9 0.3 0.0034 17.1 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF5058) FtsK_4TM PF13491.6 EHT99177.1 - 0.02 14.6 1.1 0.02 14.6 1.1 2.4 1 1 0 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE DUF1516 PF07457.11 EHT99177.1 - 0.49 10.6 11.8 0.33 11.2 4.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1516) DHquinase_II PF01220.19 EHT99178.1 - 2.9e-60 201.9 0.0 3.3e-60 201.7 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Biotin_lipoyl PF00364.22 EHT99179.1 - 1.4e-25 88.9 1.8 1.5e-25 88.8 0.4 1.7 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EHT99179.1 - 6.8e-06 25.8 0.3 0.1 12.5 0.0 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like RnfC_N PF13375.6 EHT99179.1 - 0.0023 17.9 1.0 0.0045 16.9 0.3 1.7 1 1 1 2 2 2 1 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 EHT99179.1 - 0.012 15.5 1.4 0.024 14.6 0.2 2.0 2 1 0 2 2 2 0 Glycine cleavage H-protein YqfD PF06898.11 EHT99179.1 - 0.073 11.9 0.6 0.35 9.7 0.6 1.9 1 1 0 1 1 1 0 Putative stage IV sporulation protein YqfD CPSase_L_D2 PF02786.17 EHT99180.1 - 3.3e-85 284.9 0.0 5.1e-85 284.3 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EHT99180.1 - 8.1e-44 148.7 0.2 2e-43 147.4 0.0 1.8 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EHT99180.1 - 5.5e-38 129.4 0.0 1.1e-37 128.4 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 EHT99180.1 - 8.3e-09 35.3 0.0 2e-08 34.0 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 EHT99180.1 - 8.6e-08 32.4 0.0 1.5e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 EHT99180.1 - 9.1e-08 31.9 0.0 1.7e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 EHT99180.1 - 0.0013 18.6 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 EHT99180.1 - 0.0053 16.4 0.0 0.042 13.4 0.0 2.2 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 EHT99180.1 - 0.016 14.8 0.1 0.069 12.7 0.0 2.2 3 1 0 3 3 3 0 ATP-grasp domain ATPgrasp_ST PF14397.6 EHT99180.1 - 0.1 11.8 0.1 0.23 10.7 0.0 1.5 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp DUF997 PF06196.12 EHT99181.1 - 2.3e-25 88.4 1.2 2.6e-25 88.2 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF997) SSF PF00474.17 EHT99182.1 - 5.3e-124 414.2 26.4 6.7e-124 413.8 26.4 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family PrmA PF06325.13 EHT99183.1 - 1.8e-103 346.0 0.0 2e-103 345.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EHT99183.1 - 1.8e-09 37.6 0.0 2.7e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EHT99183.1 - 2.2e-09 37.1 0.0 3.3e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EHT99183.1 - 4.2e-08 33.8 0.0 8.8e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EHT99183.1 - 1.3e-06 28.4 0.0 2.2e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EHT99183.1 - 3.9e-06 27.4 0.0 1.1e-05 25.9 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EHT99183.1 - 4.2e-06 27.4 0.0 9.1e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EHT99183.1 - 9.8e-05 22.2 0.0 0.00016 21.5 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 EHT99183.1 - 0.00012 21.7 0.0 0.00028 20.6 0.0 1.5 2 0 0 2 2 2 1 Conserved hypothetical protein 95 N6_N4_Mtase PF01555.18 EHT99183.1 - 0.00024 20.9 0.0 0.0003 20.6 0.0 1.2 1 0 0 1 1 1 1 DNA methylase Methyltransf_18 PF12847.7 EHT99183.1 - 0.00025 21.0 0.0 0.0004 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EHT99183.1 - 0.00046 20.2 0.0 0.00072 19.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EHT99183.1 - 0.002 17.1 0.0 0.0031 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.19 EHT99183.1 - 0.0062 16.3 0.0 0.0099 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.18 EHT99183.1 - 0.0079 15.9 1.0 0.035 13.8 1.0 1.9 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 CMAS PF02353.20 EHT99183.1 - 0.038 13.3 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_15 PF09445.10 EHT99183.1 - 0.092 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Dus PF01207.17 EHT99184.1 - 1.7e-114 382.1 0.0 1.9e-114 381.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 EHT99184.1 - 7.3e-06 25.6 0.1 0.0023 17.5 0.1 1.9 1 1 1 2 2 2 2 Histidine biosynthesis protein DHO_dh PF01180.21 EHT99184.1 - 0.0013 18.0 0.0 0.27 10.4 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase Oxidored_FMN PF00724.20 EHT99184.1 - 0.0088 15.4 0.4 1.2 8.3 0.0 2.6 3 0 0 3 3 3 2 NADH:flavin oxidoreductase / NADH oxidase family NMO PF03060.15 EHT99184.1 - 0.0095 15.4 1.0 0.017 14.5 0.1 1.8 2 0 0 2 2 2 1 Nitronate monooxygenase NanE PF04131.14 EHT99184.1 - 0.012 14.8 0.2 0.043 13.0 0.0 2.0 1 1 2 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase ThiG PF05690.14 EHT99184.1 - 0.033 13.5 1.1 0.72 9.1 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG PEP_mutase PF13714.6 EHT99184.1 - 0.063 12.7 0.0 0.16 11.4 0.0 1.6 1 1 0 1 1 1 0 Phosphoenolpyruvate phosphomutase IMPDH PF00478.25 EHT99184.1 - 0.063 12.3 0.7 2.1 7.3 0.0 2.2 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain MR_MLE_C PF13378.6 EHT99184.1 - 0.09 12.3 0.0 0.33 10.5 0.0 1.9 2 0 0 2 2 2 0 Enolase C-terminal domain-like HTH_8 PF02954.19 EHT99185.1 - 2.6e-14 52.7 0.4 3.8e-14 52.2 0.4 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family Phage_NinH PF06322.11 EHT99185.1 - 0.00055 19.8 0.1 0.0011 18.8 0.1 1.5 1 0 0 1 1 1 1 Phage NinH protein DUF3333 PF11812.8 EHT99185.1 - 0.026 14.7 0.2 0.03 14.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3333) HTH_30 PF13556.6 EHT99185.1 - 0.11 12.3 0.1 0.26 11.1 0.0 1.7 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain ABC_tran PF00005.27 EHT99186.1 - 1.3e-36 126.2 0.0 1.6e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EHT99186.1 - 8.8e-09 35.6 0.0 0.00074 19.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EHT99186.1 - 5.9e-06 25.9 0.0 6.5e-05 22.5 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EHT99186.1 - 0.00032 20.5 0.0 0.047 13.4 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EHT99186.1 - 0.0007 19.9 0.0 0.0015 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EHT99186.1 - 0.0012 19.3 0.0 0.0017 18.8 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EHT99186.1 - 0.0012 18.5 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Rad17 PF03215.15 EHT99186.1 - 0.0015 18.5 0.3 0.0058 16.6 0.0 1.9 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_33 PF13671.6 EHT99186.1 - 0.002 18.3 0.0 0.0031 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EHT99186.1 - 0.0021 17.2 0.0 0.004 16.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DAP3 PF10236.9 EHT99186.1 - 0.0021 17.3 0.0 0.32 10.1 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 AAA_18 PF13238.6 EHT99186.1 - 0.0049 17.4 0.0 0.0083 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EHT99186.1 - 0.0074 16.2 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 EHT99186.1 - 0.0075 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EHT99186.1 - 0.015 15.7 0.0 4.3 7.8 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EHT99186.1 - 0.017 15.6 0.0 0.024 15.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 EHT99186.1 - 0.017 14.3 0.0 0.033 13.4 0.0 1.3 1 1 0 1 1 1 0 G-protein alpha subunit AAA_28 PF13521.6 EHT99186.1 - 0.032 14.5 0.1 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EHT99186.1 - 0.064 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SbcCD_C PF13558.6 EHT99186.1 - 0.067 13.4 0.3 0.91 9.8 0.3 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.6 EHT99186.1 - 0.077 13.3 0.1 0.11 12.8 0.1 1.4 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EHT99186.1 - 0.085 12.1 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF815 PF05673.13 EHT99186.1 - 0.09 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) cobW PF02492.19 EHT99186.1 - 0.1 12.2 0.0 0.13 11.9 0.0 1.3 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 EHT99186.1 - 0.11 12.9 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 EHT99186.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain PCP_red PF08369.10 EHT99186.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit ATPase_2 PF01637.18 EHT99186.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DnaJ PF00226.31 EHT99187.1 - 7.3e-09 35.6 0.1 7.8e-09 35.5 0.1 1.1 1 0 0 1 1 1 1 DnaJ domain NIL PF09383.10 EHT99187.1 - 0.15 12.0 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 NIL domain HTH_Tnp_1 PF01527.20 EHT99188.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT99188.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT99188.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT99188.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHT99189.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHT99190.1 - 1.1e-97 326.9 4.5 3.8e-97 325.1 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT99190.1 - 3.2e-16 59.3 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT99190.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT99190.1 - 8.7e-11 42.4 9.0 1.9e-10 41.4 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Phage_HK97_TLTM PF06120.11 EHT99190.1 - 0.011 15.0 0.8 0.021 14.0 0.8 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHT99190.1 - 0.02 15.2 4.2 0.084 13.2 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain UME PF08064.13 EHT99190.1 - 0.033 14.1 0.3 20 5.1 0.0 3.1 2 1 1 3 3 3 0 UME (NUC010) domain Exonuc_VII_L PF02601.15 EHT99190.1 - 0.039 13.5 2.7 0.04 13.5 1.0 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Troponin PF00992.20 EHT99190.1 - 0.044 14.1 2.8 0.078 13.3 2.8 1.3 1 0 0 1 1 1 0 Troponin FUSC PF04632.12 EHT99190.1 - 0.048 12.2 7.4 0.077 11.5 7.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tho2 PF11262.8 EHT99190.1 - 0.049 12.8 0.6 0.081 12.1 0.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FAM184 PF15665.5 EHT99190.1 - 0.052 13.3 8.0 0.082 12.7 8.0 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B HalX PF08663.10 EHT99190.1 - 0.13 12.6 2.4 0.34 11.3 2.4 1.7 1 0 0 1 1 1 0 HalX domain LXG PF04740.12 EHT99190.1 - 0.14 11.8 2.8 0.35 10.5 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHT99190.1 - 0.19 11.5 11.1 0.31 10.8 11.1 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DHR10 PF18595.1 EHT99190.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Zn-ribbon_8 PF09723.10 EHT99190.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF1192 PF06698.11 EHT99190.1 - 0.54 10.4 5.3 3.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHT99190.1 - 0.82 8.9 3.0 1.2 8.3 3.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHT99190.1 - 2 8.0 8.1 4.3 6.8 8.1 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHT99190.1 - 4.2 7.7 8.6 8.7 6.7 8.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CREPT PF16566.5 EHT99190.1 - 5.9 7.1 8.7 2.7 8.1 5.6 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour SlyX PF04102.12 EHT99190.1 - 9.3 7.0 9.0 18 6.1 2.3 3.0 1 1 1 2 2 2 0 SlyX DDE_3 PF13358.6 EHT99192.1 - 1.1e-22 80.3 0.0 1.8e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 EHT99192.1 - 1.1e-10 41.0 1.0 3.5e-09 36.2 0.1 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 EHT99192.1 - 4e-09 37.0 1.1 2.7e-08 34.3 0.3 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 EHT99192.1 - 3.9e-07 30.0 1.2 1.1e-06 28.6 0.3 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_33 PF13592.6 EHT99192.1 - 2.1e-06 27.3 4.7 4.4e-06 26.3 0.3 3.0 3 0 0 3 3 3 1 Winged helix-turn helix HTH_28 PF13518.6 EHT99192.1 - 1.4e-05 25.2 0.3 0.0002 21.4 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHT99192.1 - 0.031 14.8 0.2 0.061 13.9 0.2 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 HTH_38 PF13936.6 EHT99192.1 - 0.051 13.3 0.6 0.15 11.8 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain DDE_Tnp_IS66 PF03050.14 EHT99193.1 - 1.1e-97 326.9 4.5 3.8e-97 325.1 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT99193.1 - 3.2e-16 59.3 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT99193.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT99193.1 - 8.7e-11 42.4 9.0 1.9e-10 41.4 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Phage_HK97_TLTM PF06120.11 EHT99193.1 - 0.011 15.0 0.8 0.021 14.0 0.8 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHT99193.1 - 0.02 15.2 4.2 0.084 13.2 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain UME PF08064.13 EHT99193.1 - 0.033 14.1 0.3 20 5.1 0.0 3.1 2 1 1 3 3 3 0 UME (NUC010) domain Exonuc_VII_L PF02601.15 EHT99193.1 - 0.039 13.5 2.7 0.04 13.5 1.0 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Troponin PF00992.20 EHT99193.1 - 0.044 14.1 2.8 0.078 13.3 2.8 1.3 1 0 0 1 1 1 0 Troponin FUSC PF04632.12 EHT99193.1 - 0.048 12.2 7.4 0.077 11.5 7.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tho2 PF11262.8 EHT99193.1 - 0.049 12.8 0.6 0.081 12.1 0.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FAM184 PF15665.5 EHT99193.1 - 0.052 13.3 8.0 0.082 12.7 8.0 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B HalX PF08663.10 EHT99193.1 - 0.13 12.6 2.4 0.34 11.3 2.4 1.7 1 0 0 1 1 1 0 HalX domain LXG PF04740.12 EHT99193.1 - 0.14 11.8 2.8 0.35 10.5 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHT99193.1 - 0.19 11.5 11.1 0.31 10.8 11.1 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DHR10 PF18595.1 EHT99193.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Zn-ribbon_8 PF09723.10 EHT99193.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF1192 PF06698.11 EHT99193.1 - 0.54 10.4 5.3 3.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHT99193.1 - 0.82 8.9 3.0 1.2 8.3 3.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHT99193.1 - 2 8.0 8.1 4.3 6.8 8.1 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHT99193.1 - 4.2 7.7 8.6 8.7 6.7 8.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CREPT PF16566.5 EHT99193.1 - 5.9 7.1 8.7 2.7 8.1 5.6 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour SlyX PF04102.12 EHT99193.1 - 9.3 7.0 9.0 18 6.1 2.3 3.0 1 1 1 2 2 2 0 SlyX HTH_Tnp_1 PF01527.20 EHT99195.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT99195.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT99195.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT99195.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix RVT_1 PF00078.27 EHT99196.1 - 8.5e-43 146.4 0.0 1.7e-42 145.5 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) GIIM PF08388.11 EHT99196.1 - 1.2e-17 63.7 4.0 3e-17 62.4 4.0 1.7 1 0 0 1 1 1 1 Group II intron, maturase-specific domain AIRC PF00731.20 EHT99199.1 - 0.1 12.2 0.2 0.1 12.2 0.2 1.1 1 0 0 1 1 1 0 AIR carboxylase Plasmid_stab_B PF10784.9 EHT99200.1 - 8.8e-47 156.8 1.1 4.7e-25 87.2 0.1 2.1 2 0 0 2 2 2 2 Plasmid stability protein T6SS_VasJ PF16989.5 EHT99200.1 - 0.085 12.3 0.0 0.18 11.3 0.0 1.7 1 1 0 1 1 1 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ StbA PF06406.11 EHT99201.1 - 8e-112 373.6 0.0 9.5e-112 373.3 0.0 1.0 1 0 0 1 1 1 1 StbA protein MreB_Mbl PF06723.13 EHT99201.1 - 0.0034 16.3 0.0 2 7.2 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein ALP_N PF17989.1 EHT99201.1 - 0.0043 17.2 0.0 0.0073 16.5 0.0 1.4 1 0 0 1 1 1 1 Actin like proteins N terminal domain Peptidase_S24 PF00717.23 EHT99202.1 - 1.2e-12 47.5 0.0 1.6e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase S24-like IMS PF00817.20 EHT99203.1 - 2.5e-33 115.2 0.1 7.2e-33 113.7 0.0 1.7 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 EHT99203.1 - 8.1e-19 68.5 0.0 1.7e-18 67.4 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4113 PF13438.6 EHT99203.1 - 2.4e-18 65.9 0.8 8.6e-18 64.2 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4113) IMS_HHH PF11798.8 EHT99203.1 - 5.5e-05 23.3 0.0 0.00014 22.0 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif DNA_pol_lambd_f PF10391.9 EHT99203.1 - 0.0012 18.6 1.3 0.01 15.6 0.0 3.0 4 0 0 4 4 4 1 Fingers domain of DNA polymerase lambda Cdd1 PF11731.8 EHT99203.1 - 0.031 14.5 0.0 0.084 13.1 0.0 1.8 1 0 0 1 1 1 0 Pathogenicity locus Rep_3 PF01051.21 EHT99204.1 - 4e-38 131.5 0.0 4.4e-38 131.3 0.0 1.0 1 0 0 1 1 1 1 Initiator Replication protein Lip_A_acyltrans PF03279.13 EHT99204.1 - 0.038 13.2 0.0 0.052 12.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial lipid A biosynthesis acyltransferase DUF790 PF05626.11 EHT99205.1 - 0.019 13.7 0.0 0.021 13.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF790) Phage_integrase PF00589.22 EHT99206.1 - 1.1e-41 142.5 0.0 1.4e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family Malate_synthase PF01274.22 EHT99206.1 - 0.03 12.6 0.0 0.038 12.3 0.0 1.1 1 0 0 1 1 1 0 Malate synthase Peptidase_M50 PF02163.22 EHT99207.1 - 7.8e-11 41.7 0.6 9.1e-11 41.5 0.6 1.1 1 0 0 1 1 1 1 Peptidase family M50 Peptidase_M50B PF13398.6 EHT99207.1 - 1.9e-06 27.6 8.6 9.4e-06 25.4 8.6 2.0 1 1 0 1 1 1 1 Peptidase M50B-like DUF3267 PF11667.8 EHT99207.1 - 0.005 17.1 6.7 0.032 14.5 6.7 2.0 1 1 0 1 1 1 1 Putative zincin peptidase Tail_VII PF17091.5 EHT99207.1 - 0.24 11.3 1.8 6.9 6.6 0.1 2.5 2 0 0 2 2 2 0 Inovirus G7P protein LBP_C PF17386.2 EHT99208.1 - 0.18 11.7 0.1 0.27 11.2 0.1 1.3 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase C-terminal domain DDE_Tnp_IS66 PF03050.14 EHT99210.1 - 6.9e-98 327.6 2.6 6.2e-97 324.4 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT99210.1 - 3.5e-16 59.1 0.1 1.3e-15 57.3 0.1 2.1 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT99210.1 - 1.4e-14 54.2 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT99210.1 - 1.2e-11 45.2 9.0 2.6e-11 44.1 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHT99210.1 - 0.017 14.9 6.4 0.027 14.3 6.4 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Phage_HK97_TLTM PF06120.11 EHT99210.1 - 0.022 14.0 1.7 0.042 13.0 1.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHT99210.1 - 0.022 15.1 4.3 0.091 13.1 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain FUSC PF04632.12 EHT99210.1 - 0.038 12.5 6.8 0.06 11.9 6.8 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 EHT99210.1 - 0.04 13.5 2.2 0.047 13.2 0.8 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Tho2 PF11262.8 EHT99210.1 - 0.057 12.6 0.5 0.094 11.9 0.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Troponin PF00992.20 EHT99210.1 - 0.062 13.6 3.0 0.11 12.8 3.0 1.3 1 0 0 1 1 1 0 Troponin LXG PF04740.12 EHT99210.1 - 0.11 12.3 2.5 0.32 10.7 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily UME PF08064.13 EHT99210.1 - 0.15 12.0 0.5 21 5.1 0.0 3.1 2 1 1 3 3 3 0 UME (NUC010) domain ERM PF00769.19 EHT99210.1 - 0.16 11.8 10.8 0.26 11.1 10.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HalX PF08663.10 EHT99210.1 - 0.23 11.8 3.1 0.59 10.5 3.1 1.7 1 0 0 1 1 1 0 HalX domain DHR10 PF18595.1 EHT99210.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Zn-ribbon_8 PF09723.10 EHT99210.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF1192 PF06698.11 EHT99210.1 - 0.53 10.4 5.3 3.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHT99210.1 - 1.1 8.4 3.1 1.7 7.8 3.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHT99210.1 - 2.8 7.4 7.9 6.1 6.3 7.9 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHT99210.1 - 3.3 8.1 7.9 6.7 7.0 7.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 EHT99210.1 - 7.4 7.3 8.7 7.7 7.2 1.0 3.0 1 1 1 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHT99211.1 - 7.4e-39 131.7 0.0 8.3e-39 131.6 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHT99212.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT99212.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT99212.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT99212.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix ParE_toxin PF05016.15 EHT99213.1 - 1.3e-13 51.4 0.0 1.4e-13 51.2 0.0 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE ParD_antitoxin PF03693.14 EHT99214.1 - 5.8e-20 71.5 0.1 6.8e-20 71.3 0.1 1.1 1 0 0 1 1 1 1 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH RHH_1 PF01402.21 EHT99214.1 - 0.002 18.0 4.0 0.0022 17.8 1.2 2.1 1 1 1 2 2 2 1 Ribbon-helix-helix protein, copG family IstB_IS21 PF01695.17 EHT99215.1 - 6.5e-28 97.7 0.0 8.1e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 IstB-like ATP binding protein Bac_DnaA PF00308.18 EHT99215.1 - 0.0012 18.8 0.0 0.0014 18.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial dnaA protein IstB_IS21 PF01695.17 EHT99216.1 - 1.7e-11 44.1 0.0 2e-11 44.0 0.0 1.0 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF2240 PF09999.9 EHT99216.1 - 0.054 13.1 0.0 0.054 13.1 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2240) F-box-like PF12937.7 EHT99217.1 - 0.00023 21.0 0.0 0.00048 20.0 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EHT99217.1 - 0.003 17.4 0.0 0.0063 16.4 0.0 1.5 1 0 0 1 1 1 1 F-box F-box PF00646.33 EHT99217.1 - 0.0052 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.6 EHT99217.1 - 0.013 15.4 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 F-box-like domain PRANC PF09372.10 EHT99217.1 - 0.15 12.4 0.0 0.41 11.0 0.0 1.7 1 0 0 1 1 1 0 PRANC domain DUF5585 PF17823.1 EHT99217.1 - 0.35 9.8 4.7 0.49 9.3 4.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5585) DUF5585 PF17823.1 EHT99218.1 - 0.44 9.4 5.2 0.63 8.9 5.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5585) RHS_repeat PF05593.14 EHT99221.1 - 9.9e-27 93.0 64.4 4.1e-08 33.6 1.7 16.3 12 4 4 16 16 16 13 RHS Repeat Big_2 PF02368.18 EHT99222.1 - 0.0022 17.9 5.5 0.056 13.3 0.7 4.1 3 0 0 3 3 3 1 Bacterial Ig-like domain (group 2) AAA_5 PF07728.14 EHT99222.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Phage_lysozyme PF00959.19 EHT99223.1 - 3.5e-28 98.2 0.0 4.3e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Phage lysozyme DDE_Tnp_Tn3 PF01526.17 EHT99223.1 - 0.15 10.8 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Tn3 transposase DDE domain HTH_Tnp_1 PF01527.20 EHT99224.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT99224.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT99224.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT99224.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHT99225.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHT99226.1 - 2.6e-97 325.7 3.5 1.2e-96 323.5 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT99226.1 - 3.4e-16 59.2 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT99226.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT99226.1 - 1.2e-11 45.2 9.0 2.6e-11 44.1 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHT99226.1 - 0.017 14.9 6.4 0.027 14.3 6.4 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Phage_HK97_TLTM PF06120.11 EHT99226.1 - 0.022 14.0 1.7 0.042 13.0 1.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHT99226.1 - 0.022 15.1 4.3 0.091 13.1 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain FUSC PF04632.12 EHT99226.1 - 0.038 12.5 6.8 0.06 11.9 6.8 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 EHT99226.1 - 0.04 13.5 2.2 0.047 13.2 0.8 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Tho2 PF11262.8 EHT99226.1 - 0.057 12.6 0.5 0.094 11.9 0.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Troponin PF00992.20 EHT99226.1 - 0.062 13.6 3.0 0.11 12.8 3.0 1.3 1 0 0 1 1 1 0 Troponin LXG PF04740.12 EHT99226.1 - 0.11 12.3 2.5 0.32 10.7 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily UME PF08064.13 EHT99226.1 - 0.15 12.0 0.5 21 5.1 0.0 3.1 2 1 1 3 3 3 0 UME (NUC010) domain ERM PF00769.19 EHT99226.1 - 0.16 11.8 10.8 0.26 11.1 10.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HalX PF08663.10 EHT99226.1 - 0.23 11.8 3.1 0.59 10.5 3.1 1.7 1 0 0 1 1 1 0 HalX domain DHR10 PF18595.1 EHT99226.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Zn-ribbon_8 PF09723.10 EHT99226.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF1192 PF06698.11 EHT99226.1 - 0.53 10.4 5.3 3.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHT99226.1 - 1.1 8.4 3.1 1.7 7.8 3.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHT99226.1 - 2.8 7.4 7.9 6.1 6.3 7.9 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHT99226.1 - 3.3 8.1 7.9 6.7 7.0 7.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 EHT99226.1 - 7.5 7.3 8.7 7.7 7.2 1.0 3.0 1 1 1 2 2 2 0 SlyX DUF1967 PF09269.11 EHT99227.1 - 0.023 14.6 0.0 0.024 14.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) DUF1419 PF07215.11 EHT99228.1 - 0.0013 18.8 0.0 0.0023 18.0 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1419) TrwB_AAD_bind PF10412.9 EHT99229.1 - 3.1e-72 243.6 0.0 3.8e-72 243.3 0.0 1.1 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain TraG-D_C PF12696.7 EHT99229.1 - 5.5e-20 71.6 0.0 9.5e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG T4SS-DNA_transf PF02534.14 EHT99229.1 - 2.4e-14 53.0 0.0 3.2e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer AAA_30 PF13604.6 EHT99230.1 - 0.0012 18.6 0.5 0.0018 18.1 0.5 1.2 1 0 0 1 1 1 1 AAA domain Thioredoxin_4 PF13462.6 EHT99232.1 - 1.9e-17 63.9 0.0 4.7e-17 62.6 0.0 1.6 1 1 1 2 2 2 1 Thioredoxin ScsC_N PF18312.1 EHT99232.1 - 3.4e-12 46.0 1.9 8.5e-12 44.7 1.9 1.7 1 0 0 1 1 1 1 Copper resistance protein ScsC N-terminal domain DSBA PF01323.20 EHT99232.1 - 1.5e-10 41.2 1.2 3e-09 36.9 1.2 2.3 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 EHT99232.1 - 5.8e-05 23.5 0.0 0.00015 22.2 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.20 EHT99232.1 - 0.016 15.2 0.2 0.29 11.1 0.1 2.4 2 0 0 2 2 2 0 Thioredoxin DUF3197 PF11432.8 EHT99232.1 - 0.04 13.8 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3197) IncFII_repA PF02387.15 EHT99233.1 - 4.5e-09 35.9 0.0 5.7e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 IncFII RepA protein family DDE_Tnp_Tn3 PF01526.17 EHT99234.1 - 1.3e-87 294.1 0.0 1.5e-87 293.9 0.0 1.0 1 0 0 1 1 1 1 Tn3 transposase DDE domain DDE_Tnp_Tn3 PF01526.17 EHT99235.1 - 8e-102 340.9 0.0 1.1e-101 340.5 0.0 1.1 1 0 0 1 1 1 1 Tn3 transposase DDE domain AAA_2 PF07724.14 EHT99236.1 - 6.6e-58 195.6 0.0 1.5e-55 187.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EHT99236.1 - 3.3e-35 120.1 5.0 3.3e-35 120.1 5.0 2.7 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 EHT99236.1 - 1.7e-28 98.5 2.3 3.6e-28 97.4 0.2 2.8 3 0 0 3 3 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EHT99236.1 - 4.4e-27 95.1 0.0 1.7e-13 51.1 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Clp_N PF02861.20 EHT99236.1 - 4e-26 90.9 5.4 7.9e-13 48.3 0.1 3.1 3 0 0 3 3 2 2 Clp amino terminal domain, pathogenicity island component AAA_5 PF07728.14 EHT99236.1 - 6e-19 68.4 0.0 2.7e-13 50.1 0.0 3.0 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EHT99236.1 - 9.7e-13 48.8 6.2 5e-05 23.8 0.0 5.1 5 1 0 6 6 4 2 AAA ATPase domain Sigma54_activat PF00158.26 EHT99236.1 - 3.9e-09 36.4 0.0 4e-06 26.6 0.0 3.0 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 EHT99236.1 - 7.6e-08 32.7 6.1 0.0058 16.9 0.1 5.0 3 3 0 3 3 3 2 AAA domain TniB PF05621.11 EHT99236.1 - 2.3e-06 27.1 0.0 0.015 14.7 0.0 3.8 2 2 0 2 2 2 1 Bacterial TniB protein AAA_18 PF13238.6 EHT99236.1 - 4.2e-06 27.3 0.1 0.32 11.6 0.0 4.1 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 EHT99236.1 - 6.7e-06 25.9 0.0 0.043 13.6 0.0 2.9 2 0 0 2 2 2 2 IstB-like ATP binding protein RuvB_N PF05496.12 EHT99236.1 - 1.7e-05 24.6 1.0 1.6 8.5 0.0 4.6 4 1 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 EHT99236.1 - 3.3e-05 23.9 0.8 2.2 8.1 0.2 4.1 3 1 1 4 4 4 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EHT99236.1 - 4.9e-05 23.4 0.0 0.27 11.3 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_7 PF12775.7 EHT99236.1 - 5.9e-05 22.6 0.0 0.14 11.7 0.0 2.7 3 0 0 3 3 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 EHT99236.1 - 6.5e-05 22.7 0.0 0.048 13.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EHT99236.1 - 0.00026 21.3 0.0 0.92 9.9 0.0 3.0 3 0 0 3 3 2 2 RNA helicase Roc PF08477.13 EHT99236.1 - 0.00036 20.7 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 EHT99236.1 - 0.00075 19.8 1.2 0.49 10.6 0.2 3.7 2 1 1 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 EHT99236.1 - 0.0008 19.4 0.0 1.8 8.4 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase Mg_chelatase PF01078.21 EHT99236.1 - 0.00083 18.8 0.1 1.4 8.2 0.0 3.4 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EHT99236.1 - 0.00088 19.2 0.0 0.19 11.6 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_3 PF07726.11 EHT99236.1 - 0.0012 18.7 0.0 0.79 9.6 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 EHT99236.1 - 0.0012 18.8 0.0 1.7 8.6 0.0 2.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 EHT99236.1 - 0.0021 17.3 0.0 0.56 9.3 0.0 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF815) ResIII PF04851.15 EHT99236.1 - 0.0057 16.7 0.0 5.7 6.9 0.0 3.5 2 1 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_33 PF13671.6 EHT99236.1 - 0.016 15.4 0.0 8.5 6.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EHT99236.1 - 0.019 14.5 0.0 1.3 8.5 0.0 3.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EHT99236.1 - 0.022 15.2 2.5 4.8 7.7 0.0 3.5 3 1 0 3 3 3 0 ABC transporter NTPase_1 PF03266.15 EHT99236.1 - 0.025 14.5 0.0 8.9 6.2 0.0 2.8 2 0 0 2 2 2 0 NTPase DNA_pol3_delta2 PF13177.6 EHT99236.1 - 0.025 14.3 0.0 7.2 6.4 0.0 2.7 2 0 0 2 2 2 0 DNA polymerase III, delta subunit Zeta_toxin PF06414.12 EHT99236.1 - 0.027 13.8 0.0 4.7 6.4 0.0 2.8 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.6 EHT99236.1 - 0.028 14.8 0.1 1.2 9.5 0.1 3.0 3 1 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 EHT99236.1 - 0.035 13.9 0.0 1.2 8.8 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 EHT99236.1 - 0.046 13.5 0.0 13 5.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain SRP54 PF00448.22 EHT99236.1 - 0.047 13.3 0.0 1.4 8.5 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Root_cap PF06830.11 EHT99236.1 - 0.062 13.4 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 Root cap PduV-EutP PF10662.9 EHT99236.1 - 0.086 12.6 0.0 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MEDS PF14417.6 EHT99236.1 - 0.41 10.5 3.7 0.87 9.4 0.6 2.9 3 0 0 3 3 3 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain AAA_23 PF13476.6 EHT99236.1 - 7.2 7.1 25.8 8.3 6.9 0.0 4.3 2 1 1 3 3 2 0 AAA domain Cu-oxidase_4 PF02578.15 EHT99237.1 - 2e-80 269.7 0.1 2.3e-80 269.5 0.1 1.0 1 0 0 1 1 1 1 Multi-copper polyphenol oxidoreductase laccase PseudoU_synth_2 PF00849.22 EHT99238.1 - 4.2e-32 111.4 0.2 6.1e-32 110.9 0.2 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 EHT99238.1 - 1e-11 44.4 0.1 1.7e-11 43.7 0.1 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 EHT99238.1 - 0.012 15.4 0.4 0.046 13.5 0.2 1.9 2 0 0 2 2 2 0 S4 domain YfiO PF13525.6 EHT99239.1 - 1.4e-81 273.1 7.8 1.6e-81 272.9 7.8 1.0 1 0 0 1 1 1 1 Outer membrane lipoprotein TPR_18 PF13512.6 EHT99239.1 - 9.5e-67 223.6 11.0 1.9e-66 222.6 6.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EHT99239.1 - 0.0013 19.2 3.8 3.2 8.6 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EHT99239.1 - 0.0016 18.6 2.9 1.9 8.8 0.0 3.3 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 EHT99239.1 - 0.019 14.7 0.3 0.019 14.7 0.3 2.1 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain Beta-lactamase2 PF13354.6 EHT99239.1 - 0.056 13.0 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase enzyme family TPR_9 PF13371.6 EHT99239.1 - 0.077 13.2 1.3 1.2 9.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EHT99239.1 - 0.12 12.9 0.4 0.12 12.9 0.4 3.8 3 2 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EHT99239.1 - 0.3 12.0 5.2 2.4 9.2 0.1 3.9 2 2 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 EHT99239.1 - 3.5 8.4 10.1 35 5.2 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_S30AE PF02482.19 EHT99240.1 - 3.4e-23 82.2 0.2 4e-23 82.0 0.2 1.1 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein YjcZ PF13990.6 EHT99240.1 - 0.012 15.0 0.1 0.013 14.9 0.1 1.0 1 0 0 1 1 1 0 YjcZ-like protein DUF1690 PF07956.11 EHT99240.1 - 0.048 14.1 0.2 0.066 13.6 0.2 1.1 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) PDT PF00800.18 EHT99241.1 - 4.8e-61 205.8 0.0 7.7e-61 205.1 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydratase CM_2 PF01817.21 EHT99241.1 - 6.2e-15 55.3 2.7 1.5e-14 54.1 2.7 1.7 1 0 0 1 1 1 1 Chorismate mutase type II PDH PF02153.17 EHT99242.1 - 4e-30 104.7 0.0 6.3e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase CM_2 PF01817.21 EHT99242.1 - 5.8e-21 74.6 0.2 1.3e-20 73.5 0.2 1.6 1 0 0 1 1 1 1 Chorismate mutase type II NmrA PF05368.13 EHT99242.1 - 0.21 11.1 0.0 0.32 10.5 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family DAHP_synth_1 PF00793.20 EHT99243.1 - 8e-105 349.6 0.0 9.9e-105 349.3 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Acetyltransf_3 PF13302.7 EHT99244.1 - 1.3e-20 74.5 0.1 1.5e-20 74.3 0.1 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EHT99244.1 - 3.2e-09 37.0 0.0 4.1e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EHT99244.1 - 0.011 15.7 0.0 0.068 13.1 0.0 1.9 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 EHT99244.1 - 0.054 13.2 0.0 0.071 12.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ FR47 PF08445.10 EHT99244.1 - 0.087 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein 7tm_1 PF00001.21 EHT99245.1 - 0.057 12.7 0.0 0.059 12.7 0.0 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) CcmD PF04995.14 EHT99245.1 - 0.057 13.5 1.1 0.17 12.0 1.1 1.7 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF4752 PF15944.5 EHT99245.1 - 0.078 13.0 0.5 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4752) DUF3273 PF11677.8 EHT99245.1 - 0.53 9.5 4.0 0.77 9.0 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3273) Ribosomal_L19 PF01245.20 EHT99246.1 - 4e-50 168.4 4.2 4.4e-50 168.3 4.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L19 MG2 PF01835.19 EHT99246.1 - 0.1 13.1 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 MG2 domain tRNA_m1G_MT PF01746.21 EHT99247.1 - 3.2e-72 242.3 0.0 3.9e-72 242.1 0.0 1.1 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase RimM PF01782.18 EHT99248.1 - 2.1e-27 95.1 0.0 3.1e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 RimM N-terminal domain PRC PF05239.16 EHT99248.1 - 3.3e-08 33.5 0.5 6.6e-08 32.5 0.5 1.5 1 0 0 1 1 1 1 PRC-barrel domain DUF2846 PF11008.8 EHT99248.1 - 0.033 14.2 0.0 0.055 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2846) Ribosomal_S16 PF00886.19 EHT99249.1 - 8.5e-25 86.6 0.0 1e-24 86.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 SRP54 PF00448.22 EHT99250.1 - 1.3e-75 253.4 0.5 2e-75 252.7 0.5 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EHT99250.1 - 5e-34 116.9 5.9 5e-34 116.9 5.9 3.1 4 0 0 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.19 EHT99250.1 - 2.4e-22 78.9 2.5 3.5e-22 78.4 0.2 2.6 3 0 0 3 3 2 1 SRP54-type protein, helical bundle domain CbiA PF01656.23 EHT99250.1 - 3.4e-07 30.4 0.0 2.3e-06 27.7 0.0 2.4 3 1 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 EHT99250.1 - 6.4e-05 22.3 0.0 0.00013 21.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin cobW PF02492.19 EHT99250.1 - 0.00012 21.7 0.2 0.00034 20.2 0.2 1.7 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 EHT99250.1 - 0.00022 21.0 0.9 0.00055 19.7 0.3 2.0 2 0 0 2 2 2 1 AAA domain AAA_31 PF13614.6 EHT99250.1 - 0.001 19.0 0.5 0.012 15.5 0.2 2.4 1 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EHT99250.1 - 0.0013 19.0 0.0 0.0039 17.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 EHT99250.1 - 0.0057 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Helicase AAA_33 PF13671.6 EHT99250.1 - 0.0059 16.8 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EHT99250.1 - 0.01 15.5 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain VirC1 PF07015.11 EHT99250.1 - 0.015 14.6 0.0 0.033 13.5 0.0 1.6 1 0 0 1 1 1 0 VirC1 protein Nse4-Nse3_bdg PF15412.6 EHT99250.1 - 0.016 15.3 0.2 0.13 12.4 0.1 2.6 3 0 0 3 3 3 0 Binding domain of Nse4/EID3 to Nse3-MAGE Peptidase_C23 PF05379.11 EHT99250.1 - 0.033 14.3 0.0 14 5.9 0.0 2.6 2 0 0 2 2 2 0 Carlavirus endopeptidase AAA_16 PF13191.6 EHT99250.1 - 0.036 14.4 0.0 0.14 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain APS_kinase PF01583.20 EHT99250.1 - 0.05 13.5 0.0 0.16 11.9 0.0 1.9 1 0 0 1 1 1 0 Adenylylsulphate kinase KTI12 PF08433.10 EHT99250.1 - 0.15 11.5 2.4 0.77 9.1 0.1 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 MMR_HSR1 PF01926.23 EHT99250.1 - 0.22 11.6 1.3 1.2 9.2 0.4 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase Wbp11 PF09429.10 EHT99250.1 - 1.4 9.4 4.9 4.6 7.7 1.6 2.7 2 0 0 2 2 2 0 WW domain binding protein 11 Cytochrom_C_asm PF01578.20 EHT99251.1 - 1.1e-40 139.7 20.5 1.1e-40 139.7 20.5 1.4 1 1 0 1 1 1 1 Cytochrome C assembly protein DUF21 PF01595.20 EHT99252.1 - 2.4e-49 167.4 1.6 3.5e-49 166.9 1.6 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 EHT99252.1 - 5.4e-20 71.2 0.1 1.5e-19 69.8 0.1 1.7 1 0 0 1 1 1 1 Transporter associated domain CBS PF00571.28 EHT99252.1 - 9.6e-07 29.2 0.6 0.00034 21.0 0.0 2.8 1 1 0 2 2 2 2 CBS domain LuxS PF02664.15 EHT99253.1 - 2.8e-61 205.7 0.0 3.2e-61 205.5 0.0 1.0 1 0 0 1 1 1 1 S-Ribosylhomocysteinase (LuxS) DNA_pol_lambd_f PF10391.9 EHT99253.1 - 0.16 11.8 0.0 8.3 6.3 0.0 2.6 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda Glu_cys_ligase PF04262.14 EHT99254.1 - 1.3e-170 567.0 0.0 1.6e-170 566.7 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase NA37 PF04245.13 EHT99254.1 - 0.075 12.5 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 37-kD nucleoid-associated bacterial protein SNARE_assoc PF09335.11 EHT99255.1 - 6e-08 33.2 5.9 8.3e-08 32.7 5.9 1.2 1 0 0 1 1 1 1 SNARE associated Golgi protein HAD_2 PF13419.6 EHT99256.1 - 1.9e-27 96.5 0.0 2.2e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EHT99256.1 - 1.6e-18 67.8 0.8 2.3e-17 64.0 0.8 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EHT99256.1 - 5.7e-06 26.3 0.1 5.8e-05 23.1 0.0 2.4 3 1 0 3 3 3 1 HAD-hyrolase-like HAD PF12710.7 EHT99256.1 - 0.00034 21.1 0.4 0.00059 20.3 0.4 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 EHT99256.1 - 0.23 11.0 0.1 0.47 10.0 0.1 1.4 1 1 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) CsrA PF02599.16 EHT99257.1 - 2.3e-27 94.7 1.5 2.6e-27 94.5 1.5 1.0 1 0 0 1 1 1 1 Global regulator protein family S1 PF00575.23 EHT99257.1 - 0.023 15.0 0.6 0.12 12.7 0.4 1.8 1 1 1 2 2 2 0 S1 RNA binding domain tRNA-synt_2c PF01411.19 EHT99258.1 - 1.4e-236 786.3 0.0 3.2e-236 785.1 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (A) DHHA1 PF02272.19 EHT99258.1 - 2.5e-29 102.5 2.6 7.4e-29 100.9 2.6 1.9 1 0 0 1 1 1 1 DHHA1 domain tRNA_SAD PF07973.14 EHT99258.1 - 1.4e-17 63.5 0.1 5.6e-17 61.6 0.1 2.1 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF3573 PF12097.8 EHT99258.1 - 0.0043 15.9 0.8 0.0076 15.1 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3573) Phage_cap_E PF03864.15 EHT99258.1 - 0.029 13.6 0.2 0.065 12.4 0.2 1.6 1 0 0 1 1 1 0 Phage major capsid protein E FH2 PF02181.23 EHT99258.1 - 0.95 8.5 3.1 0.43 9.7 0.4 1.7 2 0 0 2 2 2 0 Formin Homology 2 Domain LPP PF04728.13 EHT99258.1 - 1.1 9.7 9.7 12 6.4 0.0 3.2 3 0 0 3 3 3 0 Lipoprotein leucine-zipper Spc7 PF08317.11 EHT99258.1 - 4.8 6.0 5.7 2 7.2 1.4 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein RecX PF02631.16 EHT99259.1 - 9.5e-32 110.0 0.8 4e-31 108.0 0.1 1.9 2 0 0 2 2 2 1 RecX family RecA PF00154.21 EHT99260.1 - 9.4e-142 471.1 3.4 1.1e-141 470.8 3.4 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 EHT99260.1 - 9.6e-13 48.0 0.7 2.4e-12 46.7 0.7 1.6 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 EHT99260.1 - 1.4e-09 37.6 0.3 2.6e-08 33.5 0.3 2.5 1 1 0 1 1 1 1 KaiC ATPase_2 PF01637.18 EHT99260.1 - 1.9e-05 24.7 0.0 5.6e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EHT99260.1 - 4.5e-05 23.3 0.0 6.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EHT99260.1 - 0.00043 20.7 0.0 0.00076 19.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 EHT99260.1 - 0.00055 19.6 1.0 0.03 13.9 1.0 2.4 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 EHT99260.1 - 0.0069 16.5 0.0 0.011 15.8 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_35 PF14516.6 EHT99260.1 - 0.012 14.4 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain PAXNEB PF05625.11 EHT99260.1 - 0.015 14.5 0.5 0.023 13.9 0.5 1.2 1 0 0 1 1 1 0 PAXNEB protein CobU PF02283.16 EHT99260.1 - 0.017 14.7 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA PF00004.29 EHT99260.1 - 0.022 15.2 0.1 0.048 14.1 0.1 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.14 EHT99260.1 - 0.024 14.6 0.0 0.11 12.4 0.0 2.0 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.6 EHT99260.1 - 0.038 14.0 0.0 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain TK PF00265.18 EHT99260.1 - 0.046 13.6 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 Thymidine kinase AAA_22 PF13401.6 EHT99260.1 - 0.052 13.8 0.0 0.11 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain CinA PF02464.17 EHT99261.1 - 1.2e-60 203.6 1.1 1.4e-60 203.4 1.1 1.0 1 0 0 1 1 1 1 Competence-damaged protein PhnA PF03831.14 EHT99262.1 - 4.1e-34 116.3 3.5 5.1e-34 116.0 3.5 1.1 1 0 0 1 1 1 1 PhnA domain PhnA_Zn_Ribbon PF08274.12 EHT99262.1 - 8.8e-09 35.2 3.4 1.4e-08 34.5 3.4 1.4 1 0 0 1 1 1 1 PhnA Zinc-Ribbon TF_Zn_Ribbon PF08271.12 EHT99262.1 - 0.0026 17.2 0.7 0.0043 16.5 0.1 1.8 2 1 0 2 2 2 1 TFIIB zinc-binding zinc_ribbon_4 PF13717.6 EHT99262.1 - 0.0062 16.4 2.6 0.088 12.8 2.6 2.3 1 1 0 1 1 1 1 zinc-ribbon domain zinc-ribbons_6 PF07191.12 EHT99262.1 - 0.026 14.5 0.9 0.039 13.9 0.9 1.3 1 0 0 1 1 1 0 zinc-ribbons zf-TFIIIC PF12660.7 EHT99262.1 - 0.036 14.0 0.5 0.059 13.3 0.5 1.3 1 0 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex zf-Mss51 PF13824.6 EHT99262.1 - 0.038 14.1 1.0 0.064 13.4 1.0 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-RRN7 PF11781.8 EHT99262.1 - 0.047 13.4 1.4 0.3 10.8 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-RING_UBOX PF13445.6 EHT99262.1 - 0.054 13.5 0.6 0.087 12.9 0.6 1.4 1 0 0 1 1 1 0 RING-type zinc-finger HypA PF01155.19 EHT99262.1 - 0.06 13.4 0.5 0.06 13.4 0.5 1.6 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RPA_interact_C PF14768.6 EHT99262.1 - 0.065 13.8 0.3 0.075 13.6 0.3 1.4 1 1 0 1 1 1 0 Replication protein A interacting C-terminal DUF2318 PF10080.9 EHT99262.1 - 0.093 12.9 0.6 0.12 12.5 0.5 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2318) DUF983 PF06170.12 EHT99262.1 - 0.1 13.0 1.2 6.2 7.3 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF983) DNA_RNApol_7kD PF03604.13 EHT99262.1 - 0.12 12.1 0.4 0.29 10.9 0.4 1.6 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit UPF0547 PF10571.9 EHT99262.1 - 0.14 12.3 2.9 0.39 10.8 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-C2H2_3 PF13878.6 EHT99262.1 - 0.16 11.9 0.3 18 5.3 0.0 2.4 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO zf-ribbon_3 PF13248.6 EHT99262.1 - 0.3 10.5 0.1 0.3 10.5 0.1 2.6 3 0 0 3 3 3 0 zinc-ribbon domain YacG PF03884.14 EHT99262.1 - 0.31 10.8 4.0 4.8 7.0 4.3 2.2 1 1 1 2 2 2 0 DNA gyrase inhibitor YacG Zn-ribbon_8 PF09723.10 EHT99262.1 - 0.73 10.0 5.0 18 5.6 4.7 2.3 1 1 1 2 2 2 0 Zinc ribbon domain SLT_2 PF13406.6 EHT99263.1 - 1.9e-90 303.1 0.0 2.2e-90 302.9 0.0 1.0 1 0 0 1 1 1 1 Transglycosylase SLT domain Glucosaminidase PF01832.20 EHT99263.1 - 0.01 16.3 0.0 0.023 15.2 0.0 1.6 1 0 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase SLT PF01464.20 EHT99263.1 - 0.032 13.9 0.0 0.18 11.5 0.0 2.1 1 1 0 1 1 1 0 Transglycosylase SLT domain MutS_V PF00488.21 EHT99264.1 - 6.9e-89 296.9 0.1 1.3e-88 295.9 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 EHT99264.1 - 6.9e-43 145.5 0.0 1.9e-42 144.1 0.0 1.8 2 0 0 2 2 2 1 MutS domain I MutS_III PF05192.18 EHT99264.1 - 2e-40 139.1 0.6 4.2e-40 138.0 0.6 1.6 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 EHT99264.1 - 1.5e-33 115.9 0.0 3.7e-33 114.7 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 EHT99264.1 - 2e-29 101.8 0.0 4.5e-29 100.7 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_14 PF13173.6 EHT99264.1 - 0.036 14.1 0.0 0.095 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain HTH_3 PF01381.22 EHT99265.1 - 9.6e-16 57.6 0.5 1.6e-15 56.9 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix 2TM PF13239.6 EHT99265.1 - 1.2e-13 51.2 0.7 2e-13 50.5 0.7 1.4 1 0 0 1 1 1 1 2TM domain HTH_31 PF13560.6 EHT99265.1 - 1.1e-09 38.5 0.5 2.5e-09 37.4 0.1 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 EHT99265.1 - 1.6e-08 34.4 0.0 9.1e-08 32.0 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_26 PF13443.6 EHT99265.1 - 1.2e-07 32.0 0.0 5.1e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 EHT99265.1 - 5.7e-06 26.1 0.1 9.1e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 EHT99265.1 - 0.0089 15.8 0.4 0.031 14.1 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_17 PF12728.7 EHT99265.1 - 0.026 14.7 0.1 2.7 8.2 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain Frag1 PF10277.9 EHT99265.1 - 0.027 14.0 1.0 0.038 13.5 1.0 1.1 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family HTH_29 PF13551.6 EHT99265.1 - 0.032 14.2 0.4 0.13 12.3 0.1 2.0 2 0 0 2 2 2 0 Winged helix-turn helix Sigma70_r4 PF04545.16 EHT99265.1 - 0.039 13.5 0.2 0.1 12.1 0.2 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Crp_2 PF13545.6 EHT99265.1 - 0.053 13.5 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain DUF2207 PF09972.9 EHT99265.1 - 0.14 10.9 0.0 0.16 10.7 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) YfhO PF09586.10 EHT99265.1 - 0.26 9.5 0.4 0.31 9.2 0.4 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Tom5 PF10642.9 EHT99265.1 - 2.8 8.0 4.7 6.5 6.9 0.2 3.0 3 0 0 3 3 3 0 Mitochondrial import receptor subunit or translocase 2-ph_phosp PF04029.14 EHT99266.1 - 5.4e-21 74.8 0.0 9.1e-21 74.1 0.0 1.3 1 1 0 1 1 1 1 2-phosphosulpholactate phosphatase Sigma70_r3 PF04539.16 EHT99267.1 - 1.8e-22 79.2 2.8 9.8e-21 73.6 1.5 2.5 2 0 0 2 2 2 1 Sigma-70 region 3 Sigma70_r2 PF04542.14 EHT99267.1 - 1.6e-21 75.8 0.6 3.3e-21 74.8 0.2 1.8 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 EHT99267.1 - 3.8e-17 61.5 3.7 2.5e-15 55.7 2.8 2.6 2 0 0 2 2 2 2 Sigma-70, region 4 Sigma70_r1_2 PF00140.20 EHT99267.1 - 9.6e-11 41.5 0.1 3e-10 39.9 0.1 1.9 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 Peptidase_M23 PF01551.22 EHT99268.1 - 1.3e-31 108.7 0.8 1.3e-31 108.7 0.8 2.6 3 1 0 3 3 3 1 Peptidase family M23 LysM PF01476.20 EHT99268.1 - 3.5e-11 43.0 0.2 9.4e-11 41.6 0.1 1.8 2 0 0 2 2 2 1 LysM domain Biotin_lipoyl_2 PF13533.6 EHT99268.1 - 0.0023 17.7 0.1 0.23 11.3 0.0 3.0 3 0 0 3 3 3 1 Biotin-lipoyl like RnfC_N PF13375.6 EHT99268.1 - 0.053 13.5 1.2 3.6 7.6 0.0 3.1 3 0 0 3 3 3 0 RnfC Barrel sandwich hybrid domain PCMT PF01135.19 EHT99269.1 - 6.9e-74 248.1 0.0 8.1e-74 247.9 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EHT99269.1 - 7.7e-06 25.8 0.0 1.1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EHT99269.1 - 1.7e-05 25.5 0.0 3.1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 EHT99269.1 - 7.6e-05 21.9 0.0 0.0001 21.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.12 EHT99269.1 - 0.0012 19.4 0.0 0.003 18.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 EHT99269.1 - 0.011 14.9 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_23 PF13489.6 EHT99269.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.10 EHT99269.1 - 0.12 12.0 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit SurE PF01975.17 EHT99270.1 - 6.2e-59 199.1 0.1 7.5e-59 198.8 0.1 1.1 1 0 0 1 1 1 1 Survival protein SurE TruD PF01142.18 EHT99271.1 - 2.5e-66 224.2 0.0 4.6e-45 154.2 0.0 2.0 1 1 1 2 2 2 2 tRNA pseudouridine synthase D (TruD) YgbB PF02542.16 EHT99272.1 - 8.1e-66 221.1 0.0 9.1e-66 220.9 0.0 1.0 1 0 0 1 1 1 1 YgbB family IspD PF01128.19 EHT99273.1 - 2.3e-80 269.5 0.0 2.6e-80 269.3 0.0 1.0 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transf_3 PF12804.7 EHT99273.1 - 1.7e-15 57.8 2.0 2.3e-15 57.3 2.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain DivIC PF04977.15 EHT99274.1 - 7.8e-29 99.3 0.7 2.3e-28 97.8 0.0 1.8 1 1 1 2 2 2 1 Septum formation initiator DUF3561 PF12084.8 EHT99275.1 - 5.1e-43 145.4 7.5 5.6e-43 145.3 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3561) APS_kinase PF01583.20 EHT99276.1 - 8e-74 246.8 0.0 1e-73 246.4 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 EHT99276.1 - 9.2e-08 32.4 0.0 1.6e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EHT99276.1 - 0.00027 21.5 0.0 0.00042 20.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 EHT99276.1 - 0.00073 19.6 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain KTI12 PF08433.10 EHT99276.1 - 0.0031 17.0 0.0 0.0043 16.5 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_16 PF13191.6 EHT99276.1 - 0.0052 17.2 0.3 0.0073 16.7 0.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EHT99276.1 - 0.006 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ParA PF10609.9 EHT99276.1 - 0.011 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase PRK PF00485.18 EHT99276.1 - 0.012 15.3 0.2 0.042 13.6 0.0 1.9 1 1 1 2 2 2 0 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.22 EHT99276.1 - 0.024 14.3 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 EHT99276.1 - 0.031 14.0 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 EHT99276.1 - 0.033 14.3 0.0 0.058 13.5 0.0 1.3 1 0 0 1 1 1 0 Torsin Zeta_toxin PF06414.12 EHT99276.1 - 0.033 13.5 0.0 0.096 12.0 0.0 1.8 1 1 0 1 1 1 0 Zeta toxin CPT PF07931.12 EHT99276.1 - 0.056 13.3 1.0 0.64 9.8 1.0 2.1 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_22 PF13401.6 EHT99276.1 - 0.064 13.5 0.0 0.099 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EHT99276.1 - 0.083 13.4 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_17 PF13207.6 EHT99276.1 - 0.089 13.2 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 EHT99276.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 EHT99276.1 - 0.15 11.8 0.1 0.3 10.8 0.1 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 EHT99276.1 - 0.25 11.8 0.0 0.44 10.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase GTP_EFTU PF00009.27 EHT99277.1 - 8.7e-43 146.1 0.0 1.2e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EHT99277.1 - 9.7e-07 28.9 0.0 1.6e-05 24.9 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 EHT99277.1 - 1.1e-06 28.9 0.2 2.8e-06 27.6 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SRPRB PF09439.10 EHT99277.1 - 0.012 15.0 0.0 0.88 9.0 0.0 2.3 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EHT99277.1 - 0.014 14.9 0.0 0.073 12.6 0.0 2.2 2 1 0 2 2 2 0 Ferrous iron transport protein B Roc PF08477.13 EHT99277.1 - 0.018 15.2 0.0 7.3 6.8 0.0 2.5 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 EHT99277.1 - 0.045 13.6 1.3 8.9 6.2 0.1 2.7 1 1 0 2 2 2 0 RsgA GTPase cobW PF02492.19 EHT99277.1 - 0.19 11.3 0.5 0.98 9.0 0.5 2.1 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain PAPS_reduct PF01507.19 EHT99278.1 - 5.9e-65 218.5 0.0 7.1e-65 218.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family TP_methylase PF00590.20 EHT99279.1 - 1.9e-49 168.5 0.7 3.1e-49 167.8 0.7 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 EHT99279.1 - 8.8e-30 103.2 0.0 2.8e-29 101.6 0.0 1.9 2 0 0 2 2 2 1 Putative NAD(P)-binding CysG_dimeriser PF10414.9 EHT99279.1 - 3.7e-21 74.6 2.9 1.1e-20 73.1 2.9 1.9 1 0 0 1 1 1 1 Sirohaem synthase dimerisation region Sirohm_synth_M PF14824.6 EHT99279.1 - 1.1e-07 31.2 0.1 2.6e-07 30.0 0.1 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Radical_SAM PF04055.21 EHT99279.1 - 0.0062 16.9 0.0 0.17 12.2 0.0 2.6 2 1 0 2 2 2 1 Radical SAM superfamily Shikimate_DH PF01488.20 EHT99279.1 - 0.11 12.6 0.1 0.33 11.0 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase AdoHcyase_NAD PF00670.21 EHT99279.1 - 0.17 12.0 0.0 0.51 10.4 0.0 1.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Peptidase_M28 PF04389.17 EHT99280.1 - 1.8e-20 73.5 0.0 2.5e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 YCII PF03795.14 EHT99281.1 - 3.1e-10 40.3 0.0 3.7e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain IclR PF01614.18 EHT99282.1 - 1.2e-12 47.7 0.0 1.9e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 EHT99282.1 - 1.7e-11 43.7 0.3 4.9e-11 42.3 0.1 1.9 2 0 0 2 2 2 1 IclR helix-turn-helix domain TrmB PF01978.19 EHT99282.1 - 2.9e-06 27.0 0.0 1.1e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 EHT99282.1 - 0.00031 20.6 0.2 0.00074 19.3 0.1 1.7 2 0 0 2 2 2 1 MarR family HTH_20 PF12840.7 EHT99282.1 - 0.013 15.6 0.1 0.026 14.6 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_5 PF01022.20 EHT99282.1 - 0.087 12.7 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Ribonuc_L-PSP PF01042.21 EHT99283.1 - 6.3e-21 74.6 0.0 7.8e-21 74.3 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP HTH_Tnp_1 PF01527.20 EHT99284.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT99284.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT99284.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT99284.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHT99285.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHT99286.1 - 2.6e-97 325.7 3.5 1.2e-96 323.5 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT99286.1 - 3.4e-16 59.2 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT99286.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT99286.1 - 1.2e-11 45.2 9.0 2.6e-11 44.1 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHT99286.1 - 0.017 14.9 6.4 0.027 14.3 6.4 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Phage_HK97_TLTM PF06120.11 EHT99286.1 - 0.022 14.0 1.7 0.042 13.0 1.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHT99286.1 - 0.022 15.1 4.3 0.091 13.1 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain FUSC PF04632.12 EHT99286.1 - 0.038 12.5 6.8 0.06 11.9 6.8 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 EHT99286.1 - 0.04 13.5 2.2 0.047 13.2 0.8 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Tho2 PF11262.8 EHT99286.1 - 0.057 12.6 0.5 0.094 11.9 0.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Troponin PF00992.20 EHT99286.1 - 0.062 13.6 3.0 0.11 12.8 3.0 1.3 1 0 0 1 1 1 0 Troponin LXG PF04740.12 EHT99286.1 - 0.11 12.3 2.5 0.32 10.7 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily UME PF08064.13 EHT99286.1 - 0.15 12.0 0.5 21 5.1 0.0 3.1 2 1 1 3 3 3 0 UME (NUC010) domain ERM PF00769.19 EHT99286.1 - 0.16 11.8 10.8 0.26 11.1 10.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HalX PF08663.10 EHT99286.1 - 0.23 11.8 3.1 0.59 10.5 3.1 1.7 1 0 0 1 1 1 0 HalX domain DHR10 PF18595.1 EHT99286.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Zn-ribbon_8 PF09723.10 EHT99286.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF1192 PF06698.11 EHT99286.1 - 0.53 10.4 5.3 3.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHT99286.1 - 1.1 8.4 3.1 1.7 7.8 3.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHT99286.1 - 2.8 7.4 7.9 6.1 6.3 7.9 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHT99286.1 - 3.3 8.1 7.9 6.7 7.0 7.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 EHT99286.1 - 7.5 7.3 8.7 7.7 7.2 1.0 3.0 1 1 1 2 2 2 0 SlyX BPD_transp_1 PF00528.22 EHT99287.1 - 5.9e-20 71.8 20.6 5.9e-20 71.8 20.6 1.5 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 EHT99288.1 - 9.2e-20 71.2 9.8 9.2e-20 71.2 9.8 1.9 1 1 1 2 2 2 2 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 EHT99289.1 - 4.3e-35 121.2 0.0 5.3e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EHT99289.1 - 6e-10 39.4 0.0 0.00025 21.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EHT99289.1 - 2.3e-08 33.8 0.0 8.1e-08 32.0 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 EHT99289.1 - 0.00023 21.1 0.0 0.00032 20.7 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_29 PF13555.6 EHT99289.1 - 0.00062 19.5 0.1 0.0012 18.6 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 EHT99289.1 - 0.00075 19.7 0.6 0.01 16.1 0.6 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 EHT99289.1 - 0.0025 18.2 0.1 0.0032 17.9 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EHT99289.1 - 0.0036 17.2 0.2 0.0066 16.4 0.2 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 EHT99289.1 - 0.0092 15.7 0.9 0.015 15.0 0.9 1.7 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EHT99289.1 - 0.012 15.3 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EHT99289.1 - 0.014 15.7 0.1 0.05 13.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EHT99289.1 - 0.022 14.1 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_5 PF07728.14 EHT99289.1 - 0.028 14.4 0.0 0.33 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 EHT99289.1 - 0.033 14.6 0.0 1.6 9.2 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EHT99289.1 - 0.033 14.4 0.6 0.064 13.4 0.6 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EHT99289.1 - 0.037 14.6 0.0 0.059 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EHT99289.1 - 0.048 13.9 0.5 0.14 12.4 0.2 1.9 1 1 1 2 2 2 0 AAA domain AAA_25 PF13481.6 EHT99289.1 - 0.066 12.8 0.4 0.26 10.8 0.1 1.9 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 EHT99289.1 - 0.089 11.9 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit VirE PF05272.11 EHT99289.1 - 0.23 11.2 0.0 0.39 10.4 0.0 1.3 1 0 0 1 1 1 0 Virulence-associated protein E DDE_Tnp_1 PF01609.21 EHT99291.1 - 3.4e-20 72.6 0.0 6.1e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain D-ser_dehydrat PF14031.6 EHT99293.1 - 1.5e-14 54.4 0.0 4.3e-14 52.9 0.0 1.8 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 EHT99293.1 - 2.6e-12 46.9 0.2 3.5e-12 46.4 0.2 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain PAPS_reduct PF01507.19 EHT99294.1 - 1.4e-50 171.8 0.0 1.8e-50 171.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family NIR_SIR PF01077.22 EHT99295.1 - 4.4e-51 172.5 0.1 2.1e-45 154.1 0.1 2.2 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 EHT99295.1 - 1.8e-30 104.6 0.1 4.8e-15 55.2 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 EHT99296.1 - 6.7e-31 107.4 0.6 1.9e-30 106.0 0.2 2.0 2 0 0 2 2 2 1 Flavodoxin FAD_binding_1 PF00667.20 EHT99296.1 - 5.3e-27 94.8 0.0 5.9e-26 91.4 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EHT99296.1 - 1.5e-19 70.6 0.0 4.2e-19 69.2 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Acetyltransf_2 PF00797.17 EHT99297.1 - 2.6e-07 30.7 0.0 3.2e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 N-acetyltransferase PTPS PF01242.19 EHT99298.1 - 2.5e-34 117.9 0.0 2.7e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase Pyrophosphatase PF00719.19 EHT99299.1 - 3.2e-36 124.5 0.0 3.9e-36 124.3 0.0 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase Fer4_14 PF13394.6 EHT99300.1 - 3e-12 46.7 0.1 1.3e-11 44.7 0.1 1.9 1 1 0 1 1 1 1 4Fe-4S single cluster domain Radical_SAM PF04055.21 EHT99300.1 - 2.3e-07 31.4 0.1 3.7e-07 30.7 0.1 1.5 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EHT99300.1 - 7.3e-06 26.3 0.0 1.2e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Exo_endo_phos PF03372.23 EHT99301.1 - 1.9e-06 27.6 0.0 3.6e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Enolase_C PF00113.22 EHT99302.1 - 4.7e-140 466.0 2.9 6.2e-140 465.6 2.9 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EHT99302.1 - 1.2e-56 190.5 0.9 2.6e-56 189.4 0.9 1.6 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EHT99302.1 - 1.7e-05 24.5 0.0 3.7e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 EHT99302.1 - 0.00037 19.7 0.8 0.0016 17.7 0.1 2.1 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus CTP_synth_N PF06418.14 EHT99303.1 - 1.4e-125 418.0 0.1 1.8e-125 417.6 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EHT99303.1 - 3.2e-64 216.2 0.0 5.9e-64 215.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EHT99303.1 - 1.3e-10 41.5 0.3 1.6e-06 28.0 0.0 2.7 3 0 0 3 3 3 2 Peptidase C26 CbiA PF01656.23 EHT99303.1 - 0.014 15.4 0.0 0.024 14.7 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MazG PF03819.17 EHT99304.1 - 3.5e-38 129.6 2.0 1.3e-27 95.8 0.0 2.7 3 0 0 3 3 3 2 MazG nucleotide pyrophosphohydrolase domain PRA-PH PF01503.17 EHT99304.1 - 1.1e-08 35.3 0.1 0.0035 17.7 0.0 2.4 2 0 0 2 2 2 2 Phosphoribosyl-ATP pyrophosphohydrolase Erythro-docking PF09277.11 EHT99304.1 - 0.018 14.9 0.2 0.63 10.0 0.1 2.6 2 0 0 2 2 2 0 Erythronolide synthase, docking Ofd1_CTDD PF10637.9 EHT99304.1 - 0.09 12.1 0.0 0.13 11.6 0.0 1.4 1 1 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term DUF5063 PF16702.5 EHT99304.1 - 0.16 12.4 0.9 2.3 8.6 0.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF5063) HD_4 PF13328.6 EHT99305.1 - 3.9e-40 137.1 0.3 1e-39 135.8 0.3 1.7 1 0 0 1 1 1 1 HD domain RelA_SpoT PF04607.17 EHT99305.1 - 7.1e-36 123.0 0.0 1.7e-35 121.8 0.0 1.7 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins TGS PF02824.21 EHT99305.1 - 1.4e-21 76.2 0.2 7e-21 74.1 0.0 2.3 3 0 0 3 3 3 1 TGS domain ACT_4 PF13291.6 EHT99305.1 - 4.6e-18 65.6 1.6 1.3e-17 64.1 1.6 1.8 1 0 0 1 1 1 1 ACT domain ACT PF01842.25 EHT99305.1 - 2.9e-11 42.9 1.3 1.1e-10 41.1 0.3 2.5 2 0 0 2 2 2 1 ACT domain ACT_6 PF13740.6 EHT99305.1 - 0.054 13.5 0.1 0.18 11.8 0.1 1.8 1 0 0 1 1 1 0 ACT domain DUF2688 PF10892.8 EHT99305.1 - 0.17 11.4 0.0 4.2 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) Latarcin PF10279.9 EHT99305.1 - 1.2 9.6 4.4 3.8 8.0 0.8 3.0 3 0 0 3 3 3 0 Latarcin precursor tRNA_U5-meth_tr PF05958.11 EHT99306.1 - 2.4e-29 102.4 0.0 1.7e-27 96.3 0.0 2.7 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase TRAM PF01938.20 EHT99306.1 - 1.6e-10 40.8 0.1 3.3e-10 39.8 0.1 1.5 1 0 0 1 1 1 1 TRAM domain Methyltransf_31 PF13847.6 EHT99306.1 - 3.1e-08 33.6 0.0 7.5e-08 32.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 EHT99306.1 - 1.1e-06 28.6 0.0 2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 EHT99306.1 - 1.9e-05 23.8 0.0 4.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EHT99306.1 - 2.1e-05 25.1 0.0 7.2e-05 23.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EHT99306.1 - 0.00037 20.1 0.0 0.00096 18.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 EHT99306.1 - 0.0025 17.5 0.0 0.0048 16.6 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 EHT99306.1 - 0.0027 17.5 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.6 EHT99306.1 - 0.0049 16.7 0.9 0.043 13.6 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain DOT1 PF08123.13 EHT99306.1 - 0.013 15.1 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_4 PF02390.17 EHT99306.1 - 0.013 15.0 0.1 0.033 13.6 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase PDGF PF00341.17 EHT99306.1 - 0.084 13.2 0.1 0.2 12.0 0.1 1.6 1 0 0 1 1 1 0 PDGF/VEGF domain N6_N4_Mtase PF01555.18 EHT99306.1 - 0.17 11.5 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 DNA methylase DUF2222 PF09984.9 EHT99307.1 - 5.1e-49 166.0 0.2 1.4e-48 164.6 0.2 1.8 1 0 0 1 1 1 1 Uncharacterised signal transduction histidine kinase domain (DUF2222) HATPase_c PF02518.26 EHT99307.1 - 2.8e-30 105.1 0.7 5.5e-30 104.2 0.7 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EHT99307.1 - 2.3e-26 92.2 1.1 1.1e-24 86.7 0.8 2.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 EHT99307.1 - 7e-19 67.6 0.1 7e-19 67.6 0.1 3.5 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain Hpt PF01627.23 EHT99307.1 - 1.9e-12 47.2 1.7 1.9e-12 47.2 1.7 2.3 2 0 0 2 2 2 1 Hpt domain HAMP PF00672.25 EHT99307.1 - 1.3e-07 31.8 0.9 3.6e-07 30.5 0.9 1.8 1 0 0 1 1 1 1 HAMP domain HATPase_c_2 PF13581.6 EHT99307.1 - 0.08 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 EHT99307.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase PF00069.25 EHT99307.1 - 0.14 11.5 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain Laminin_I PF06008.14 EHT99307.1 - 0.67 9.6 8.4 1.8 8.2 1.1 2.4 2 0 0 2 2 2 0 Laminin Domain I Gly_kinase PF02595.15 EHT99308.1 - 5.6e-150 499.4 10.3 6.3e-150 499.2 10.3 1.0 1 0 0 1 1 1 1 Glycerate kinase family NAD_binding_2 PF03446.15 EHT99309.1 - 5.3e-48 163.2 2.5 8.1e-48 162.6 2.5 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EHT99309.1 - 2.1e-39 134.5 1.0 3.3e-39 133.9 1.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 EHT99309.1 - 5.1e-08 33.4 1.7 3.1e-07 30.9 0.2 2.4 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EHT99309.1 - 1.3e-07 31.2 0.2 2.7e-07 30.1 0.2 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PDH PF02153.17 EHT99309.1 - 0.0016 17.5 0.4 0.0024 16.9 0.4 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase 3HCDH_N PF02737.18 EHT99309.1 - 0.0029 17.5 0.8 0.2 11.5 0.1 2.6 2 1 1 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 EHT99309.1 - 0.003 17.1 0.3 0.0089 15.6 0.1 1.9 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 EHT99309.1 - 0.017 15.2 1.1 0.04 14.0 0.1 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_N PF05222.15 EHT99309.1 - 0.042 14.1 0.0 0.095 13.0 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, N-terminal domain Epimerase PF01370.21 EHT99309.1 - 0.045 13.2 0.1 0.21 11.0 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family UDPG_MGDP_dh PF00984.19 EHT99309.1 - 0.1 12.8 0.2 0.26 11.5 0.2 1.8 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 EHT99309.1 - 0.1 13.0 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain HpcH_HpaI PF03328.14 EHT99310.1 - 4.8e-57 192.6 0.0 5.5e-57 192.4 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.21 EHT99310.1 - 0.00059 18.8 0.0 0.00084 18.3 0.0 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PEP-utilizers_C PF02896.18 EHT99310.1 - 0.024 13.7 0.2 0.74 8.9 0.2 2.5 1 1 1 2 2 2 0 PEP-utilising enzyme, TIM barrel domain MR_MLE_C PF13378.6 EHT99311.1 - 8.9e-40 136.6 0.3 1.3e-39 136.1 0.3 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EHT99311.1 - 1.7e-05 25.0 0.1 3e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MFS_1 PF07690.16 EHT99312.1 - 7.3e-59 199.5 44.9 7.2e-51 173.2 25.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EHT99312.1 - 0.0081 15.1 45.6 0.012 14.6 18.0 3.7 2 2 1 3 3 3 2 Sugar (and other) transporter DUF2407_C PF13373.6 EHT99312.1 - 0.039 14.1 2.5 0.33 11.1 2.5 2.3 1 1 0 1 1 1 0 DUF2407 C-terminal domain Ndc1_Nup PF09531.10 EHT99312.1 - 9.7 4.7 6.9 15 4.1 6.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GD_AH_C PF04295.13 EHT99313.1 - 1e-143 478.9 0.0 1.2e-143 478.7 0.0 1.0 1 0 0 1 1 1 1 D-galactarate dehydratase / Altronate hydrolase, C terminus SAF PF08666.12 EHT99313.1 - 2.7e-12 47.1 0.7 1.6e-11 44.6 0.1 2.6 3 0 0 3 3 3 1 SAF domain Flavodoxin_1 PF00258.25 EHT99314.1 - 5.2e-21 75.4 0.0 5.8e-21 75.2 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin FMN_red PF03358.15 EHT99314.1 - 0.18 11.5 0.0 1.3 8.7 0.0 2.3 1 1 1 3 3 3 0 NADPH-dependent FMN reductase PseudoU_synth_2 PF00849.22 EHT99315.1 - 3e-28 98.9 0.0 3.7e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase DUF446 PF04287.12 EHT99316.1 - 1.3e-32 111.7 4.0 1.5e-32 111.6 4.0 1.0 1 0 0 1 1 1 1 tRNA pseudouridine synthase C Syd PF07348.12 EHT99317.1 - 7.2e-71 237.5 0.0 8.1e-71 237.3 0.0 1.0 1 0 0 1 1 1 1 Syd protein (SUKH-2) QueF_N PF14819.6 EHT99318.1 - 2.2e-47 159.9 0.0 9.3e-47 157.9 0.0 1.9 2 0 0 2 2 2 1 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term QueF PF14489.6 EHT99318.1 - 2.5e-33 114.1 0.0 1.5e-27 95.5 0.0 2.4 2 0 0 2 2 2 2 QueF-like protein DUF3412 PF11892.8 EHT99319.1 - 1.8e-57 192.6 0.0 3.3e-57 191.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3412) DUF4478 PF14793.6 EHT99319.1 - 4.8e-47 158.3 0.1 1.3e-46 157.0 0.1 1.8 1 0 0 1 1 1 1 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases Lysine_decarbox PF03641.14 EHT99319.1 - 5.7e-33 113.8 0.0 9.2e-33 113.1 0.0 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 EHT99319.1 - 1.5e-06 27.9 0.0 2.8e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 SLOG cluster4 family 5_3_exonuc_N PF02739.16 EHT99320.1 - 8.9e-29 100.4 0.0 1.3e-28 99.9 0.0 1.3 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 EHT99320.1 - 4.8e-23 81.6 0.0 7.9e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 EHT99320.1 - 0.0032 17.5 0.0 0.0085 16.2 0.0 1.7 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 EHT99320.1 - 0.0076 16.8 0.0 0.021 15.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain RlmM_FDX PF18125.1 EHT99321.1 - 2.3e-31 108.1 0.4 5e-31 107.0 0.4 1.6 1 0 0 1 1 1 1 RlmM ferredoxin-like domain FtsJ PF01728.19 EHT99321.1 - 2.1e-09 37.7 0.0 8.4e-09 35.8 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase Spt5-NGN PF03439.13 EHT99321.1 - 0.0025 17.7 0.0 0.0051 16.7 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section DUF4222 PF13973.6 EHT99321.1 - 0.046 13.3 0.0 1.3 8.7 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4222) MIT_C PF16565.5 EHT99321.1 - 0.19 11.7 0.0 0.46 10.5 0.0 1.5 2 0 0 2 2 2 0 Phospholipase D-like domain at C-terminus of MIT DUF423 PF04241.15 EHT99322.1 - 2.7e-18 66.0 7.1 3.3e-18 65.7 7.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF423) LysR_substrate PF03466.20 EHT99323.1 - 1.3e-38 132.4 0.2 2.1e-38 131.8 0.2 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EHT99323.1 - 1e-21 76.6 1.8 1.8e-21 75.8 1.8 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 EHT99323.1 - 0.054 13.3 0.3 0.11 12.4 0.3 1.4 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain DUF903 PF06004.12 EHT99324.1 - 1.9e-26 91.7 2.1 2.2e-26 91.5 2.1 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF903) Lysis_col PF02402.16 EHT99324.1 - 0.061 13.0 0.1 0.086 12.5 0.1 1.3 1 0 0 1 1 1 0 Lysis protein Pirin PF02678.16 EHT99324.1 - 0.12 12.4 0.1 0.13 12.3 0.1 1.3 1 1 0 1 1 1 0 Pirin Aminotran_5 PF00266.19 EHT99325.1 - 9.1e-137 455.9 0.0 1e-136 455.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EHT99325.1 - 0.015 14.6 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EHT99325.1 - 0.021 13.4 0.0 0.034 12.7 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme MccV PF17508.2 EHT99325.1 - 0.034 14.7 0.1 0.14 12.7 0.1 2.1 1 0 0 1 1 1 0 Microcin V bacteriocin SelA PF03841.13 EHT99325.1 - 0.041 12.9 0.0 0.066 12.2 0.0 1.2 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase SufE PF02657.15 EHT99326.1 - 2.3e-40 137.3 0.0 2.6e-40 137.1 0.0 1.0 1 0 0 1 1 1 1 Fe-S metabolism associated domain ThiF PF00899.21 EHT99327.1 - 1.7e-38 132.4 0.7 2.2e-38 132.0 0.7 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 EHT99327.1 - 0.00011 22.5 1.3 0.0006 20.1 1.3 2.0 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 EHT99327.1 - 0.0025 18.2 0.0 0.0064 16.9 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding DAO PF01266.24 EHT99327.1 - 0.0061 16.2 0.1 0.024 14.2 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 EHT99327.1 - 0.011 15.3 2.0 0.033 13.8 2.0 1.7 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 EHT99327.1 - 0.013 15.8 0.7 0.085 13.1 0.4 2.1 1 1 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 EHT99327.1 - 0.046 13.6 0.0 0.084 12.8 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 EHT99327.1 - 0.076 12.7 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase MltA PF03562.17 EHT99328.1 - 1.1e-43 149.6 1.4 2.5e-42 145.2 1.3 2.2 1 1 0 1 1 1 1 MltA specific insert domain 3D PF06725.11 EHT99328.1 - 7.6e-24 83.7 0.1 1.4e-23 82.8 0.1 1.5 1 0 0 1 1 1 1 3D domain PALP PF00291.25 EHT99329.1 - 3.2e-65 220.4 0.3 4.4e-65 220.0 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NmrA PF05368.13 EHT99329.1 - 0.19 11.3 0.1 0.27 10.7 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family Amidase_3 PF01520.18 EHT99330.1 - 1.6e-50 171.6 0.6 2.3e-50 171.2 0.6 1.2 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase AMIN PF11741.8 EHT99330.1 - 2.9e-26 91.4 0.6 5e-26 90.7 0.6 1.4 1 0 0 1 1 1 1 AMIN domain AA_kinase PF00696.28 EHT99331.1 - 7.4e-31 107.6 0.3 1e-30 107.1 0.3 1.2 1 0 0 1 1 1 1 Amino acid kinase family Acetyltransf_1 PF00583.25 EHT99331.1 - 2.9e-06 27.5 0.0 1.3e-05 25.4 0.0 2.0 1 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EHT99331.1 - 7e-06 26.4 0.0 7.4e-05 23.1 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EHT99331.1 - 0.0019 18.2 0.0 0.015 15.2 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain AAA_30 PF13604.6 EHT99332.1 - 1.2e-32 113.2 2.9 2.2e-31 109.1 0.5 2.7 2 1 1 3 3 3 1 AAA domain AAA_19 PF13245.6 EHT99332.1 - 3.6e-30 105.2 0.1 7.8e-30 104.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 EHT99332.1 - 1.3e-16 60.9 0.0 2.2e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 EHT99332.1 - 6.9e-16 57.8 0.3 1.5e-15 56.7 0.3 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EHT99332.1 - 5.8e-12 45.8 2.0 1.5e-06 28.2 0.1 3.3 2 1 1 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 EHT99332.1 - 2.2e-09 37.5 0.5 4.6e-05 23.3 0.0 2.3 1 1 1 2 2 2 2 AAA domain SH3_13 PF18335.1 EHT99332.1 - 4.7e-09 35.9 0.0 8.4e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain UvrD-helicase PF00580.21 EHT99332.1 - 5.6e-07 29.4 0.1 1.3e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 EHT99332.1 - 1.1e-05 25.7 0.1 3.3e-05 24.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain DUF2075 PF09848.9 EHT99332.1 - 4.4e-05 22.9 0.0 0.00071 18.9 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.6 EHT99332.1 - 0.00028 21.2 0.1 0.00086 19.6 0.1 1.9 1 0 0 1 1 1 1 AAA domain UvrD_C PF13361.6 EHT99332.1 - 0.00043 19.8 0.0 0.00083 18.8 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PhoH PF02562.16 EHT99332.1 - 0.0096 15.4 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein T2SSE PF00437.20 EHT99332.1 - 0.011 14.9 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 EHT99332.1 - 0.017 15.5 1.9 0.026 14.9 0.5 2.2 2 1 0 2 2 1 0 AAA ATPase domain CbiA PF01656.23 EHT99332.1 - 0.017 15.2 0.4 0.033 14.2 0.4 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 EHT99332.1 - 0.037 13.8 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EHT99332.1 - 0.078 13.4 0.1 0.17 12.3 0.1 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 EHT99332.1 - 0.097 12.3 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF4384 PF14326.6 EHT99332.1 - 0.11 12.7 0.0 0.35 11.0 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4384) FtsK_SpoIIIE PF01580.18 EHT99332.1 - 0.11 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.9 EHT99332.1 - 0.12 11.3 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain NTPase_1 PF03266.15 EHT99332.1 - 0.15 12.0 0.2 0.3 11.0 0.2 1.5 1 0 0 1 1 1 0 NTPase AAA_7 PF12775.7 EHT99332.1 - 0.16 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region MukB PF04310.12 EHT99332.1 - 0.19 11.5 0.1 0.32 10.7 0.1 1.3 1 0 0 1 1 1 0 MukB N-terminal Herpes_Helicase PF02689.14 EHT99332.1 - 0.26 9.2 0.1 10 3.9 0.0 2.0 2 0 0 2 2 2 0 Helicase TPR_14 PF13428.6 EHT99332.1 - 4.5 8.4 15.1 16 6.6 0.6 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat UvrD-helicase PF00580.21 EHT99333.1 - 1.5e-61 208.6 0.0 3e-61 207.7 0.0 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 EHT99333.1 - 2e-20 73.5 0.0 2.6e-10 40.2 0.0 3.2 1 1 1 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EHT99333.1 - 4.5e-18 66.0 0.0 3.8e-17 63.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 EHT99333.1 - 4.2e-07 29.7 0.1 0.0055 16.5 0.0 2.7 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain PDDEXK_1 PF12705.7 EHT99333.1 - 0.00017 21.6 0.1 0.0009 19.2 0.1 2.3 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily AAA_30 PF13604.6 EHT99333.1 - 0.0026 17.5 0.3 1.1 8.9 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_11 PF13086.6 EHT99333.1 - 0.07 12.9 0.0 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain Peptidase_M16_M PF16187.5 EHT99334.1 - 1.6e-52 178.5 2.2 2.9e-52 177.7 2.2 1.4 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 EHT99334.1 - 1.6e-35 122.3 0.0 1.8e-34 118.9 0.0 2.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EHT99334.1 - 1.8e-29 103.0 0.2 9.3e-20 71.4 0.0 2.9 3 0 0 3 3 3 2 Peptidase M16 inactive domain Defensin_propep PF00879.18 EHT99334.1 - 0.095 13.0 0.1 0.23 11.7 0.1 1.7 1 0 0 1 1 1 0 Defensin propeptide Exonuc_V_gamma PF04257.14 EHT99335.1 - 2.6e-295 981.7 7.2 3.3e-295 981.3 7.2 1.1 1 0 0 1 1 1 1 Exodeoxyribonuclease V, gamma subunit RecC_C PF17946.1 EHT99335.1 - 5.4e-65 218.9 3.5 5.4e-65 218.9 3.5 2.4 3 0 0 3 3 3 1 RecC C-terminal domain T2SSppdC PF12528.8 EHT99336.1 - 4.8e-19 68.9 2.4 6.3e-19 68.5 2.4 1.2 1 0 0 1 1 1 1 Type II secretion prepilin peptidase dependent protein C N_methyl PF07963.12 EHT99336.1 - 0.025 14.1 1.8 0.046 13.3 1.8 1.4 1 0 0 1 1 1 0 Prokaryotic N-terminal methylation motif DUF2509 PF10713.9 EHT99337.1 - 7.4e-26 90.8 2.9 9.1e-26 90.5 2.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2509) Thymidylat_synt PF00303.19 EHT99338.1 - 9e-127 421.7 0.0 1e-126 421.6 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase LGT PF01790.18 EHT99339.1 - 4.5e-78 261.8 10.7 5.1e-78 261.6 10.7 1.0 1 0 0 1 1 1 1 Prolipoprotein diacylglyceryl transferase DUF4328 PF14219.6 EHT99339.1 - 0.033 13.8 0.1 5.1 6.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) Adeno_E3_CR2 PF02439.15 EHT99339.1 - 0.038 13.7 0.1 4.1 7.2 0.0 2.7 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 DUF202 PF02656.15 EHT99339.1 - 1 9.8 9.5 1.3 9.5 1.4 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF202) PEP-utilizers_C PF02896.18 EHT99340.1 - 5e-104 347.5 0.0 7e-104 347.1 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilisers_N PF05524.13 EHT99340.1 - 6.6e-23 81.1 0.7 1.7e-22 79.7 0.7 1.8 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal GAF PF01590.26 EHT99340.1 - 2.4e-17 63.8 0.1 8.2e-17 62.1 0.1 2.0 1 0 0 1 1 1 1 GAF domain PEP-utilizers PF00391.23 EHT99340.1 - 7e-16 57.7 0.1 1.4e-15 56.8 0.1 1.5 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain GAF_2 PF13185.6 EHT99340.1 - 4.2e-15 56.2 0.0 8.5e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 EHT99340.1 - 7.4e-10 39.3 0.2 6.1e-09 36.3 0.2 2.3 1 1 0 1 1 1 1 GAF domain Lipase_GDSL PF00657.22 EHT99340.1 - 0.037 14.0 0.0 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase NUDIX PF00293.28 EHT99341.1 - 9.8e-28 96.8 0.1 1.3e-27 96.4 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain MutH PF02976.15 EHT99342.1 - 6.4e-34 116.1 0.0 8.4e-34 115.7 0.0 1.1 1 0 0 1 1 1 1 DNA mismatch repair enzyme MutH MvaI_BcnI PF15515.6 EHT99342.1 - 0.26 11.1 0.0 0.33 10.7 0.0 1.2 1 0 0 1 1 1 0 MvaI/BcnI restriction endonuclease family TerC PF03741.16 EHT99343.1 - 2.7e-53 180.3 14.2 3.4e-53 180.0 14.2 1.1 1 0 0 1 1 1 1 Integral membrane protein TerC family DUF3099 PF11298.8 EHT99343.1 - 0.6 10.3 5.6 0.68 10.1 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) DUF903 PF06004.12 EHT99344.1 - 5.2e-23 80.7 3.3 6.1e-23 80.5 3.3 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF903) LPAM_1 PF08139.12 EHT99344.1 - 0.012 16.0 1.8 0.02 15.4 1.8 1.3 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site CopK PF11525.8 EHT99344.1 - 0.036 13.7 1.2 0.36 10.5 0.2 2.0 1 1 1 2 2 2 0 Copper resistance protein K dCache_2 PF08269.11 EHT99344.1 - 0.092 11.9 0.0 0.1 11.7 0.0 1.0 1 0 0 1 1 1 0 Cache domain Aldo_ket_red PF00248.21 EHT99345.1 - 1.8e-73 247.3 0.0 2e-73 247.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family YdiH PF15930.5 EHT99345.1 - 0.016 15.4 0.2 0.044 13.9 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function Orn_Arg_deC_N PF02784.16 EHT99346.1 - 1.4e-56 191.7 0.0 1.7e-56 191.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EHT99346.1 - 2.1e-25 88.8 0.0 2.4e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain LuxC PF05893.14 EHT99346.1 - 0.15 11.1 0.1 0.23 10.4 0.1 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) LysR_substrate PF03466.20 EHT99347.1 - 5.1e-47 159.9 4.4 7.6e-47 159.4 4.4 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EHT99347.1 - 8.4e-18 64.1 1.5 2.2e-17 62.7 1.5 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_Crp_2 PF13545.6 EHT99347.1 - 0.044 13.7 0.4 0.11 12.5 0.4 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_30 PF13556.6 EHT99347.1 - 0.052 13.4 0.2 0.14 11.9 0.2 1.7 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain MFS_1 PF07690.16 EHT99348.1 - 9.2e-41 139.9 50.4 9.2e-41 139.9 50.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EHT99348.1 - 1e-06 27.9 19.3 1e-06 27.9 19.3 2.8 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 EHT99348.1 - 3.7e-05 23.2 45.0 4.8e-05 22.8 45.0 1.0 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Pho88 PF10032.9 EHT99348.1 - 0.052 12.8 1.7 0.1 11.8 0.1 2.1 2 0 0 2 2 2 0 Phosphate transport (Pho88) Trypsin_2 PF13365.6 EHT99349.1 - 8.9e-05 23.4 0.3 0.00021 22.2 0.3 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain DDE_Tnp_IS66 PF03050.14 EHT99350.1 - 2.7e-97 325.7 4.0 1.2e-96 323.5 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT99350.1 - 3.3e-16 59.2 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT99350.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT99350.1 - 8.7e-11 42.4 9.0 1.9e-10 41.4 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Phage_HK97_TLTM PF06120.11 EHT99350.1 - 0.011 15.0 0.8 0.021 14.0 0.8 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHT99350.1 - 0.02 15.2 4.2 0.084 13.2 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain UME PF08064.13 EHT99350.1 - 0.032 14.1 0.3 20 5.1 0.0 3.1 2 1 1 3 3 3 0 UME (NUC010) domain Exonuc_VII_L PF02601.15 EHT99350.1 - 0.039 13.5 2.7 0.04 13.5 1.0 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Troponin PF00992.20 EHT99350.1 - 0.044 14.1 2.8 0.078 13.3 2.8 1.3 1 0 0 1 1 1 0 Troponin FUSC PF04632.12 EHT99350.1 - 0.048 12.2 7.4 0.077 11.5 7.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tho2 PF11262.8 EHT99350.1 - 0.049 12.8 0.6 0.081 12.1 0.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FAM184 PF15665.5 EHT99350.1 - 0.052 13.3 8.0 0.082 12.7 8.0 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B HalX PF08663.10 EHT99350.1 - 0.13 12.6 2.4 0.34 11.3 2.4 1.7 1 0 0 1 1 1 0 HalX domain LXG PF04740.12 EHT99350.1 - 0.14 11.8 2.8 0.35 10.5 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHT99350.1 - 0.19 11.5 11.1 0.31 10.8 11.1 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DHR10 PF18595.1 EHT99350.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Zn-ribbon_8 PF09723.10 EHT99350.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF1192 PF06698.11 EHT99350.1 - 0.54 10.4 5.3 3.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHT99350.1 - 0.82 8.9 3.0 1.2 8.3 3.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHT99350.1 - 2 8.0 8.1 4.3 6.8 8.1 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHT99350.1 - 4.2 7.7 8.6 8.7 6.7 8.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CREPT PF16566.5 EHT99350.1 - 5.9 7.1 8.7 2.7 8.1 5.6 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour SlyX PF04102.12 EHT99350.1 - 9.7 6.9 9.0 18 6.1 2.3 3.0 1 1 1 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHT99351.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHT99352.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT99352.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT99352.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT99352.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix tRNA-synt_2 PF00152.20 EHT99353.1 - 3.3e-82 276.1 0.2 4.1e-82 275.8 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EHT99353.1 - 2.3e-15 56.3 0.0 4.1e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EHT99353.1 - 0.00018 21.1 1.2 0.24 10.8 0.1 2.7 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) PCRF PF03462.18 EHT99354.1 - 4.3e-59 199.6 4.1 4.5e-59 199.6 0.5 2.0 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 EHT99354.1 - 3.4e-40 136.6 1.3 6.6e-40 135.7 1.3 1.5 1 0 0 1 1 1 1 RF-1 domain TcpS PF17456.2 EHT99354.1 - 0.081 13.0 0.5 6.3 6.8 0.1 2.4 2 0 0 2 2 2 0 Toxin-coregulated pilus protein S DUF2203 PF09969.9 EHT99354.1 - 0.41 11.4 5.0 0.85 10.4 0.5 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF4140 PF13600.6 EHT99354.1 - 6 7.4 8.6 1.6 9.2 0.9 3.2 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DHHA1 PF02272.19 EHT99355.1 - 8.2e-28 97.5 0.0 1.4e-27 96.8 0.0 1.4 1 0 0 1 1 1 1 DHHA1 domain RecJ_OB PF17768.1 EHT99355.1 - 2.9e-19 69.3 0.0 4.6e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 RecJ OB domain DHH PF01368.20 EHT99355.1 - 9.3e-09 35.4 0.0 1.5e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 DHH family Thioredoxin_2 PF13098.6 EHT99356.1 - 5.9e-26 91.1 0.0 8.1e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain DsbC_N PF10411.9 EHT99356.1 - 3.6e-14 52.0 0.0 6.9e-14 51.0 0.0 1.5 1 0 0 1 1 1 1 Disulfide bond isomerase protein N-terminus DSBA PF01323.20 EHT99356.1 - 4.4e-07 29.9 0.0 0.026 14.3 0.0 2.4 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 EHT99356.1 - 0.00013 22.1 0.4 0.047 13.9 0.3 2.2 1 1 1 2 2 2 2 Thioredoxin Phage_integrase PF00589.22 EHT99357.1 - 1e-55 188.2 0.1 1.4e-55 187.7 0.1 1.2 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 EHT99357.1 - 2.1e-24 85.6 2.2 2.1e-24 85.6 2.2 2.3 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 EHT99357.1 - 4e-06 27.2 2.7 5.3e-06 26.8 0.3 2.2 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Flavodoxin_1 PF00258.25 EHT99358.1 - 7.5e-24 84.6 0.0 8.6e-24 84.4 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_3 PF12641.7 EHT99358.1 - 0.0033 17.1 0.0 0.0048 16.6 0.0 1.4 1 1 0 1 1 1 1 Flavodoxin domain Cpta_toxin PF07254.12 EHT99359.1 - 1.9e-16 60.3 6.4 2e-16 60.1 6.4 1.0 1 0 0 1 1 1 1 Membrane-bound toxin component of toxin-antitoxin system DUF2631 PF10939.8 EHT99359.1 - 0.32 10.9 2.4 0.6 10.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2631) Sdh5 PF03937.16 EHT99360.1 - 5.2e-24 84.0 0.1 5.9e-24 83.8 0.1 1.1 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase RE_XamI PF09572.10 EHT99360.1 - 0.032 13.9 0.0 0.037 13.7 0.0 1.1 1 0 0 1 1 1 0 XamI restriction endonuclease GCV_T PF01571.21 EHT99361.1 - 1.1e-06 28.2 0.0 4.3e-06 26.3 0.0 1.7 1 1 1 2 2 2 1 Aminomethyltransferase folate-binding domain DUF4128 PF13554.6 EHT99361.1 - 0.078 13.0 0.3 0.52 10.4 0.0 2.1 2 0 0 2 2 2 0 Bacteriophage related domain of unknown function HlyIII PF03006.20 EHT99362.1 - 8.8e-38 130.3 19.7 1e-37 130.1 19.7 1.0 1 0 0 1 1 1 1 Haemolysin-III related SIS PF01380.22 EHT99363.1 - 4.4e-15 55.7 0.0 6.8e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 SIS domain HTH_6 PF01418.17 EHT99363.1 - 5.8e-15 55.0 0.0 1.4e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family HTH_IclR PF09339.10 EHT99363.1 - 0.00056 19.7 0.0 0.0034 17.1 0.0 2.1 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_24 PF13412.6 EHT99363.1 - 0.0034 16.9 0.0 0.0074 15.8 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding LacI PF00356.21 EHT99363.1 - 0.009 15.8 0.0 0.056 13.2 0.0 2.4 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family SIS_2 PF13580.6 EHT99363.1 - 0.011 15.8 0.2 2.7 8.0 0.0 2.3 2 0 0 2 2 2 0 SIS domain HTH_11 PF08279.12 EHT99363.1 - 0.013 15.4 0.1 0.041 13.8 0.1 1.9 1 1 0 1 1 1 0 HTH domain RepL PF05732.11 EHT99363.1 - 0.019 14.4 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) TrmB PF01978.19 EHT99363.1 - 0.038 13.9 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB MarR PF01047.22 EHT99363.1 - 0.12 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_17 PF12728.7 EHT99363.1 - 0.14 12.3 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Glyco_hydro_1 PF00232.18 EHT99364.1 - 1.4e-127 425.9 4.9 1.6e-127 425.7 4.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.18 EHT99364.1 - 0.00043 19.8 0.0 0.0007 19.1 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) adh_short_C2 PF13561.6 EHT99365.1 - 4.8e-55 186.7 1.6 5.5e-55 186.5 1.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EHT99365.1 - 1.2e-48 165.2 0.2 1.5e-48 164.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EHT99365.1 - 6.3e-15 55.5 0.9 1.2e-14 54.6 0.9 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EHT99365.1 - 0.0013 18.3 0.2 0.0054 16.2 0.1 2.0 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EHT99365.1 - 0.013 14.9 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase GDC-P PF02347.16 EHT99366.1 - 2.6e-191 636.1 1.2 2.7e-179 596.5 0.1 3.0 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 EHT99366.1 - 3.7e-06 26.5 0.0 9.9e-06 25.0 0.0 1.7 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EHT99366.1 - 4.4e-05 22.6 0.2 0.00032 19.8 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V nsp7 PF08716.10 EHT99366.1 - 0.04 14.6 0.3 0.16 12.6 0.2 2.1 2 0 0 2 2 2 0 nsp7 replicase GFRP PF06399.13 EHT99366.1 - 0.072 13.0 0.0 0.25 11.3 0.0 1.9 1 0 0 1 1 1 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) GCV_H PF01597.19 EHT99367.1 - 3.4e-46 156.1 0.0 3.8e-46 155.9 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 EHT99367.1 - 0.019 14.9 0.0 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 EHT99367.1 - 0.028 14.2 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Biotin-requiring enzyme GCV_T PF01571.21 EHT99368.1 - 3.9e-84 282.0 0.7 4.9e-84 281.7 0.7 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 EHT99368.1 - 2e-13 50.1 0.0 4.5e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain POPLD PF08170.12 EHT99368.1 - 0.0081 16.5 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 POPLD (NUC188) domain FAD_binding_3 PF01494.19 EHT99369.1 - 1.2e-25 90.5 0.1 3.3e-25 89.1 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EHT99369.1 - 4.6e-05 23.2 0.1 6.4e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.10 EHT99369.1 - 7.6e-05 21.9 0.0 0.00016 20.9 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.12 EHT99369.1 - 0.00019 20.6 0.5 0.04 13.0 0.1 2.9 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EHT99369.1 - 0.00028 20.1 0.5 0.00057 19.1 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EHT99369.1 - 0.001 19.6 0.1 0.002 18.7 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EHT99369.1 - 0.0021 18.2 0.1 0.006 16.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EHT99369.1 - 0.0046 16.2 0.1 0.088 12.0 0.1 2.2 2 0 0 2 2 2 1 Thi4 family Trp_halogenase PF04820.14 EHT99369.1 - 0.03 13.2 0.2 6.4 5.5 0.1 2.3 2 1 0 2 2 2 0 Tryptophan halogenase TrkA_N PF02254.18 EHT99369.1 - 0.07 13.4 0.0 0.65 10.3 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_2 PF07992.14 EHT99369.1 - 0.11 11.7 0.1 0.23 10.7 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EHT99369.1 - 0.17 10.6 1.1 0.87 8.2 1.1 1.9 1 1 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 EHT99370.1 - 2.1e-27 96.3 0.6 2.6e-27 96.0 0.6 1.1 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EHT99370.1 - 5.8e-09 35.5 4.4 6.5e-08 32.0 0.6 2.7 2 1 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 EHT99370.1 - 1.4e-05 24.9 1.6 0.0022 17.6 0.5 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EHT99370.1 - 2e-05 24.0 0.3 0.0032 16.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EHT99370.1 - 2.3e-05 23.4 2.6 0.0043 16.0 0.2 2.8 2 1 0 2 2 2 2 Tryptophan halogenase NAD_binding_9 PF13454.6 EHT99370.1 - 0.00024 21.1 1.7 0.21 11.6 0.2 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding SE PF08491.10 EHT99370.1 - 0.00045 19.4 0.0 0.00065 18.8 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox PF00070.27 EHT99370.1 - 0.023 15.2 0.1 2.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EHT99370.1 - 0.039 12.6 0.4 0.091 11.4 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein PilZ PF07238.14 EHT99370.1 - 0.11 12.8 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 PilZ domain NAD_binding_8 PF13450.6 EHT99370.1 - 0.14 12.4 0.1 3.1 8.1 0.1 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Peptidase_M24 PF00557.24 EHT99371.1 - 3.9e-65 219.4 0.1 5e-65 219.1 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EHT99371.1 - 4.9e-36 123.2 0.0 9.2e-36 122.3 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain UPF0149 PF03695.13 EHT99372.1 - 1.3e-37 129.8 2.5 1.4e-37 129.6 2.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0149) DUF4042 PF13251.6 EHT99372.1 - 0.23 11.1 0.0 0.61 9.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4042) ZapA PF05164.13 EHT99373.1 - 4.1e-20 72.0 1.6 5.2e-20 71.7 1.6 1.1 1 0 0 1 1 1 1 Cell division protein ZapA Closter_coat PF01785.17 EHT99373.1 - 0.0055 16.0 0.2 0.0068 15.7 0.2 1.2 1 0 0 1 1 1 1 Closterovirus coat protein EccE PF11203.8 EHT99373.1 - 0.04 14.2 0.7 0.066 13.5 0.5 1.4 1 1 1 2 2 2 0 Putative type VII ESX secretion system translocon, EccE Bac_rhamnosid6H PF17389.2 EHT99373.1 - 0.051 12.8 0.4 0.06 12.6 0.4 1.0 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain SPACA9 PF15120.6 EHT99373.1 - 0.066 13.0 3.0 0.13 12.0 3.0 1.5 1 1 0 1 1 1 0 Sperm acrosome-associated protein 9 DUF3482 PF11981.8 EHT99373.1 - 0.3 10.4 5.3 0.37 10.2 5.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) DUF3280 PF11684.8 EHT99373.1 - 0.54 10.7 4.9 1.1 9.7 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2380) 5-FTHF_cyc-lig PF01812.20 EHT99374.1 - 1.3e-47 162.0 0.0 1.5e-47 161.9 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family 2-Hacid_dh_C PF02826.19 EHT99375.1 - 3e-52 176.6 0.0 4.6e-52 176.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EHT99375.1 - 1.2e-36 125.3 0.0 1.6e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EHT99375.1 - 2.3e-06 27.8 0.3 3.2e-05 24.2 0.1 2.3 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.25 EHT99375.1 - 1e-05 25.2 0.0 2.6e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 ACT domain AlaDh_PNT_C PF01262.21 EHT99375.1 - 0.0054 16.0 0.3 0.071 12.4 0.3 2.3 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.21 EHT99375.1 - 0.0066 16.5 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT_4 PF13291.6 EHT99375.1 - 0.019 15.6 0.0 0.047 14.3 0.0 1.6 1 0 0 1 1 1 0 ACT domain Oxidored_nitro PF00148.19 EHT99375.1 - 0.071 11.8 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase XdhC_C PF13478.6 EHT99375.1 - 0.12 12.9 0.1 0.82 10.2 0.0 2.3 2 0 0 2 2 2 0 XdhC Rossmann domain Rib_5-P_isom_A PF06026.14 EHT99376.1 - 2.2e-59 200.0 0.1 2.6e-59 199.7 0.1 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 EHT99376.1 - 0.0011 18.9 0.2 0.0059 16.6 0.0 2.1 2 0 0 2 2 2 1 DeoR C terminal sensor domain HTH_1 PF00126.27 EHT99377.1 - 1.6e-19 69.6 0.2 7.1e-19 67.5 0.1 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 EHT99377.1 - 1.4e-15 57.2 3.4 2.5e-15 56.4 3.4 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_30 PF13556.6 EHT99377.1 - 0.013 15.2 0.0 0.035 13.9 0.0 1.7 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain SIMPL PF04402.14 EHT99378.1 - 9.6e-45 153.5 9.7 1.1e-44 153.3 9.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Mod_r PF07200.13 EHT99378.1 - 0.12 12.4 2.4 0.94 9.6 2.4 2.1 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein LysE PF01810.18 EHT99379.1 - 5.8e-50 169.4 14.6 6.6e-50 169.3 14.6 1.0 1 0 0 1 1 1 1 LysE type translocator DUF485 PF04341.12 EHT99379.1 - 5.1 7.1 11.7 0.16 11.9 3.9 2.4 2 1 0 2 2 2 0 Protein of unknown function, DUF485 MS_channel PF00924.18 EHT99380.1 - 1.1e-54 185.2 1.3 1.1e-54 185.2 1.3 1.6 2 0 0 2 2 2 1 Mechanosensitive ion channel TM_helix PF05552.12 EHT99380.1 - 3.7e-12 46.0 4.9 3.7e-12 46.0 4.9 2.3 2 0 0 2 2 2 1 Conserved TM helix vATP-synt_AC39 PF01992.16 EHT99380.1 - 0.2 11.1 0.0 0.28 10.6 0.0 1.1 1 0 0 1 1 1 0 ATP synthase (C/AC39) subunit F_bP_aldolase PF01116.20 EHT99381.1 - 7.6e-89 297.9 0.0 9.2e-89 297.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II PGK PF00162.19 EHT99382.1 - 3.2e-131 437.8 0.4 3.7e-131 437.6 0.4 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Gp_dh_C PF02800.20 EHT99383.1 - 6.4e-54 181.8 0.1 9e-54 181.3 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EHT99383.1 - 1e-32 112.5 0.0 3.8e-32 110.6 0.0 1.9 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 EHT99383.1 - 0.0058 17.3 0.0 0.029 15.0 0.0 2.0 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain TrkA_N PF02254.18 EHT99383.1 - 0.026 14.8 0.0 0.061 13.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain GFO_IDH_MocA PF01408.22 EHT99383.1 - 0.026 15.4 0.1 0.056 14.3 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 EHT99383.1 - 0.085 13.0 0.0 0.27 11.4 0.0 1.9 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Transketolase_N PF00456.21 EHT99384.1 - 7.7e-169 560.9 0.0 1.1e-168 560.4 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EHT99384.1 - 1.7e-45 154.9 0.4 3.4e-45 153.9 0.0 1.7 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EHT99384.1 - 6.6e-19 68.0 0.1 1.7e-18 66.7 0.0 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 EHT99384.1 - 5e-06 25.9 0.0 0.067 12.4 0.0 2.8 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 EHT99384.1 - 0.00035 20.4 1.0 0.026 14.3 1.0 2.7 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Peptidase_M48 PF01435.18 EHT99385.1 - 7.2e-28 97.7 0.2 1.4e-27 96.8 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M48 LPAM_1 PF08139.12 EHT99385.1 - 0.019 15.5 0.4 0.04 14.4 0.4 1.5 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Arginase PF00491.21 EHT99386.1 - 3.1e-83 279.5 0.2 3.9e-83 279.2 0.2 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 EHT99386.1 - 0.19 12.0 0.1 0.27 11.4 0.1 1.4 1 0 0 1 1 1 0 UPF0489 domain ApoB100_C PF12491.8 EHT99386.1 - 0.19 11.7 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 Apolipoprotein B100 C terminal Orn_Arg_deC_N PF02784.16 EHT99387.1 - 1.2e-67 227.9 0.1 1.7e-67 227.4 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Arg_decarb_HB PF17810.1 EHT99387.1 - 2.7e-22 78.8 0.1 6.1e-22 77.7 0.1 1.6 1 0 0 1 1 1 1 Arginine decarboxylase helical bundle domain Arg_decarbox_C PF17944.1 EHT99387.1 - 1.6e-17 63.7 2.1 5.1e-17 62.2 2.1 1.9 1 0 0 1 1 1 1 Arginine decarboxylase C-terminal helical extension S-AdoMet_synt_C PF02773.16 EHT99388.1 - 2.6e-70 234.8 0.1 5.4e-70 233.8 0.0 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 EHT99388.1 - 1.5e-47 160.8 0.0 5.4e-47 159.0 0.0 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 EHT99388.1 - 5.7e-43 145.6 0.2 1.2e-42 144.6 0.2 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 EHT99388.1 - 0.039 12.7 0.6 1.2 7.8 0.1 2.6 2 1 1 3 3 3 0 S-adenosylmethionine synthetase (AdoMet synthetase) PAS_11 PF14598.6 EHT99388.1 - 0.19 11.9 0.0 0.33 11.1 0.0 1.3 1 0 0 1 1 1 0 PAS domain Sugar_tr PF00083.24 EHT99389.1 - 1.4e-138 462.6 28.6 1.5e-138 462.4 28.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EHT99389.1 - 2.7e-42 145.0 44.5 8.1e-33 113.8 16.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EHT99389.1 - 6.7e-11 41.3 5.2 6.7e-11 41.3 5.2 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 EHT99389.1 - 1.4e-10 40.4 17.9 1.8e-07 30.1 5.1 3.9 3 1 1 4 4 4 2 MFS/sugar transport protein MFS_1_like PF12832.7 EHT99389.1 - 0.002 17.1 1.0 0.002 17.1 1.0 3.3 1 1 1 2 2 2 1 MFS_1 like family SHR3_chaperone PF08229.11 EHT99389.1 - 0.0081 15.2 1.5 0.043 12.8 0.4 2.7 3 0 0 3 3 3 1 ER membrane protein SH3 Acatn PF13000.7 EHT99389.1 - 0.026 13.0 0.5 0.026 13.0 0.5 2.5 3 0 0 3 3 3 0 Acetyl-coenzyme A transporter 1 OATP PF03137.20 EHT99389.1 - 0.04 12.2 16.8 0.28 9.4 1.2 3.2 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF4381 PF14316.6 EHT99389.1 - 1.2 9.4 3.7 1.2 9.4 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) MCPsignal PF00015.21 EHT99390.1 - 3.5e-48 163.7 19.7 3.5e-48 163.7 19.7 3.3 1 1 2 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain dCache_1 PF02743.18 EHT99390.1 - 3.3e-18 66.4 0.1 3.3e-18 66.4 0.1 3.0 2 1 1 3 3 3 1 Cache domain Mur_ligase_C PF02875.21 EHT99390.1 - 0.052 13.8 0.3 3.2 8.1 0.0 2.9 1 1 1 2 2 2 0 Mur ligase family, glutamate ligase domain DUF948 PF06103.11 EHT99390.1 - 0.098 12.9 23.8 0.35 11.1 6.4 5.2 4 2 1 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF2681 PF10883.8 EHT99390.1 - 1.5 9.3 5.5 0.77 10.2 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) NACHT_N PF17100.5 EHT99390.1 - 2 8.2 11.6 0.13 12.1 2.5 2.4 1 1 0 2 2 2 0 N-terminal domain of NWD NACHT-NTPase DUF1664 PF07889.12 EHT99390.1 - 6.1 6.9 13.3 3.2 7.8 2.6 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) SprT-like PF10263.9 EHT99391.1 - 7.1e-17 61.3 0.0 1.7e-16 60.1 0.0 1.5 1 1 1 2 2 2 1 SprT-like family Zn_ribbon_SprT PF17283.2 EHT99391.1 - 2.7e-09 36.8 7.7 4.9e-09 35.9 7.7 1.4 1 0 0 1 1 1 1 SprT-like zinc ribbon domain DUF45 PF01863.17 EHT99391.1 - 0.0039 17.2 0.1 0.0065 16.5 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function DUF45 Desulfoferrod_N PF06397.12 EHT99391.1 - 0.044 13.4 0.4 0.044 13.4 0.4 1.7 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain DUF3267 PF11667.8 EHT99391.1 - 0.078 13.3 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 Putative zincin peptidase Endonuclease_1 PF04231.13 EHT99392.1 - 1e-44 153.0 8.5 1.7e-44 152.3 8.5 1.3 1 1 0 1 1 1 1 Endonuclease I Methyltrans_RNA PF04452.14 EHT99393.1 - 9.4e-73 244.3 0.1 1.1e-72 244.1 0.1 1.0 1 0 0 1 1 1 1 RNA methyltransferase zf-RING_7 PF02591.15 EHT99393.1 - 0.12 12.5 0.2 0.25 11.6 0.2 1.6 1 0 0 1 1 1 0 C4-type zinc ribbon domain GSH-S_ATP PF02955.16 EHT99394.1 - 1.1e-79 265.9 0.0 1.4e-79 265.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain GSH-S_N PF02951.14 EHT99394.1 - 8e-48 161.5 0.0 1.4e-47 160.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, N-terminal domain RimK PF08443.11 EHT99394.1 - 2.8e-10 40.1 0.0 3.9e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATPgrasp_YheCD PF14398.6 EHT99394.1 - 6.9e-08 32.0 0.0 1e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EHT99394.1 - 0.087 12.1 0.0 0.26 10.5 0.0 1.7 1 1 1 2 2 2 0 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 EHT99394.1 - 0.093 12.8 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain DUF179 PF02622.15 EHT99395.1 - 1.7e-50 171.1 0.0 1.9e-50 171.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 RuvX PF03652.15 EHT99396.1 - 1.7e-43 148.2 0.0 1.9e-43 148.1 0.0 1.0 1 0 0 1 1 1 1 Holliday junction resolvase Erythro-docking PF09277.11 EHT99396.1 - 0.063 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Erythronolide synthase, docking T2SSE PF00437.20 EHT99397.1 - 1.3e-39 135.9 0.2 1.6e-39 135.6 0.2 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 EHT99397.1 - 1.5e-05 24.1 0.1 2.8e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 EHT99397.1 - 7.4e-05 22.6 0.7 0.00022 21.0 0.7 2.0 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EHT99397.1 - 0.00011 21.8 0.1 0.00023 20.9 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EHT99397.1 - 0.00015 22.3 0.0 0.00028 21.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EHT99397.1 - 0.00016 21.9 0.0 0.0003 21.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EHT99397.1 - 0.00021 21.7 0.6 0.00049 20.5 0.5 1.7 1 1 0 1 1 1 1 AAA ATPase domain ResIII PF04851.15 EHT99397.1 - 0.00032 20.7 0.0 0.00046 20.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit FtsK_SpoIIIE PF01580.18 EHT99397.1 - 0.00037 19.9 0.0 0.00076 18.9 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family Zeta_toxin PF06414.12 EHT99397.1 - 0.0013 18.0 0.1 0.0025 17.1 0.1 1.4 1 1 0 1 1 1 1 Zeta toxin Dak1_2 PF13684.6 EHT99397.1 - 0.0017 17.5 0.0 0.0039 16.3 0.0 1.7 1 1 0 1 1 1 1 Dihydroxyacetone kinase family ABC_tran PF00005.27 EHT99397.1 - 0.0022 18.5 0.0 0.0049 17.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter DUF87 PF01935.17 EHT99397.1 - 0.0031 17.7 0.0 0.0051 16.9 0.0 1.3 1 0 0 1 1 1 1 Helicase HerA, central domain NTPase_1 PF03266.15 EHT99397.1 - 0.0045 16.9 0.6 0.33 10.8 0.1 2.5 1 1 1 2 2 2 1 NTPase SRP54 PF00448.22 EHT99397.1 - 0.0065 16.1 0.1 0.031 13.9 0.0 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NACHT PF05729.12 EHT99397.1 - 0.0069 16.3 0.1 0.065 13.1 0.0 2.5 2 1 0 2 2 2 1 NACHT domain AAA_5 PF07728.14 EHT99397.1 - 0.0082 16.1 0.2 0.027 14.5 0.2 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Ploopntkinase3 PF18751.1 EHT99397.1 - 0.016 15.2 0.4 0.039 13.9 0.0 1.8 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_19 PF13245.6 EHT99397.1 - 0.016 15.5 0.4 0.043 14.2 0.4 1.9 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EHT99397.1 - 0.029 14.0 0.6 0.071 12.7 0.6 1.7 1 1 0 1 1 1 0 AAA domain PRK PF00485.18 EHT99397.1 - 0.038 13.7 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DUF815 PF05673.13 EHT99397.1 - 0.043 13.0 0.0 0.084 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) SMC_N PF02463.19 EHT99397.1 - 0.047 13.1 0.0 0.091 12.2 0.0 1.5 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA PF00004.29 EHT99397.1 - 0.058 13.8 0.1 0.14 12.5 0.0 1.7 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 EHT99397.1 - 0.061 12.6 0.0 0.09 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DAP3 PF10236.9 EHT99397.1 - 0.065 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_7 PF12775.7 EHT99397.1 - 0.077 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Microtub_bd PF16796.5 EHT99397.1 - 0.086 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Microtubule binding AAA_28 PF13521.6 EHT99397.1 - 0.1 12.8 0.8 0.19 12.0 0.8 1.6 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EHT99397.1 - 0.1 13.1 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 EHT99397.1 - 0.13 11.4 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_14 PF13173.6 EHT99397.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EHT99397.1 - 0.2 11.6 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Ala_racemase_N PF01168.20 EHT99398.1 - 1.8e-31 109.5 2.2 2.2e-31 109.2 2.2 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Glyco_hydro_36C PF16874.5 EHT99398.1 - 0.1 13.1 0.0 0.27 11.8 0.0 1.7 1 1 0 1 1 1 0 Glycosyl hydrolase family 36 C-terminal domain YGGT PF02325.17 EHT99399.1 - 1.4e-39 134.3 16.6 1.7e-21 76.4 4.5 2.3 2 0 0 2 2 2 2 YGGT family Ham1p_like PF01725.16 EHT99400.1 - 3.8e-61 206.3 0.0 4.2e-61 206.1 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Radical_SAM PF04055.21 EHT99401.1 - 1.5e-18 67.8 0.0 2.1e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily HemN_C PF06969.16 EHT99401.1 - 4.4e-08 33.1 0.0 9.8e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 HemN C-terminal domain HTH_45 PF14947.6 EHT99401.1 - 0.027 14.5 0.0 0.18 11.8 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix Fer4_14 PF13394.6 EHT99401.1 - 0.19 11.9 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain UTRA PF07702.13 EHT99402.1 - 3.1e-23 82.2 0.0 4.4e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 UTRA domain GntR PF00392.21 EHT99402.1 - 4e-11 42.4 0.1 7.3e-11 41.6 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family RepL PF05732.11 EHT99402.1 - 0.023 14.1 0.4 0.04 13.3 0.1 1.5 2 0 0 2 2 2 0 Firmicute plasmid replication protein (RepL) PTS_EIIA_2 PF00359.22 EHT99403.1 - 2.6e-29 102.0 0.0 3.1e-29 101.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 PTS_IIB PF02302.17 EHT99404.1 - 1.1e-14 54.9 1.3 1.2e-14 54.7 1.3 1.0 1 0 0 1 1 1 1 PTS system, Lactose/Cellobiose specific IIB subunit Neur PF00064.18 EHT99404.1 - 0.12 11.1 0.0 0.13 11.0 0.0 1.0 1 0 0 1 1 1 0 Neuraminidase EIIC-GAT PF03611.14 EHT99405.1 - 3.6e-142 474.1 34.0 3.6e-142 474.1 34.0 1.6 2 0 0 2 2 2 1 PTS system sugar-specific permease component DUF2884 PF11101.8 EHT99406.1 - 2.9e-41 141.5 1.2 3.4e-41 141.2 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2884) DUF469 PF04320.14 EHT99407.1 - 1.6e-41 141.3 0.1 1.8e-41 141.1 0.1 1.0 1 0 0 1 1 1 1 Protein with unknown function (DUF469) Methyltransf_4 PF02390.17 EHT99408.1 - 1.8e-61 206.6 0.0 2.2e-61 206.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 EHT99408.1 - 0.0047 17.6 0.0 0.0074 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 EHT99408.1 - 0.011 15.0 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase TrbL PF04610.14 EHT99408.1 - 0.057 13.2 0.0 0.08 12.7 0.0 1.2 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein HTH_AraC PF00165.23 EHT99409.1 - 6.7e-22 77.1 0.2 4.5e-11 42.6 0.1 2.8 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 EHT99409.1 - 4.3e-19 68.5 0.3 9.2e-19 67.5 0.3 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Cupin_2 PF07883.11 EHT99409.1 - 0.0024 17.5 0.0 0.0041 16.8 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Rrf2 PF02082.20 EHT99409.1 - 0.011 16.1 0.1 0.026 14.9 0.1 1.6 1 0 0 1 1 1 0 Transcriptional regulator DUF908 PF06012.12 EHT99409.1 - 0.031 13.7 0.9 0.48 9.8 0.1 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) Glyco_hydro_4 PF02056.16 EHT99410.1 - 1.8e-76 255.8 0.1 2.4e-76 255.4 0.1 1.2 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase Glyco_hydro_4C PF11975.8 EHT99410.1 - 2.9e-61 207.2 0.0 3.9e-61 206.8 0.0 1.2 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase C-terminal domain DUF1320 PF07030.12 EHT99410.1 - 0.1 12.8 0.1 0.31 11.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1320) MFS_2 PF13347.6 EHT99411.1 - 1.3e-81 274.4 42.2 1.4e-81 274.2 42.2 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein HhH-GPD PF00730.25 EHT99412.1 - 6.6e-22 78.0 0.0 1.8e-21 76.6 0.0 1.7 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 EHT99412.1 - 2.1e-21 76.0 0.1 3.8e-21 75.1 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain HHH PF00633.23 EHT99412.1 - 7.8e-08 31.8 0.0 1.8e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 EHT99412.1 - 1.1e-05 25.6 5.0 2e-05 24.7 5.0 1.5 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III Iron_traffic PF04362.14 EHT99413.1 - 2.1e-40 136.3 0.2 2.4e-40 136.1 0.2 1.0 1 0 0 1 1 1 1 Bacterial Fe(2+) trafficking DUF5412 PF17428.2 EHT99413.1 - 0.028 14.2 0.1 0.039 13.8 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5412) Mltc_N PF11873.8 EHT99414.1 - 4e-67 225.0 0.0 5.7e-67 224.5 0.0 1.2 1 0 0 1 1 1 1 Membrane-bound lytic murein transglycosylase C, N-terminal domain SLT PF01464.20 EHT99414.1 - 2.3e-32 111.1 0.0 3.5e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase SLT domain Lysozyme_like PF13702.6 EHT99414.1 - 4.1e-05 23.3 1.1 0.00024 20.9 0.1 2.5 2 1 0 2 2 2 1 Lysozyme-like SLT_2 PF13406.6 EHT99414.1 - 0.0021 17.4 0.0 0.0043 16.3 0.0 1.5 1 0 0 1 1 1 1 Transglycosylase SLT domain Glucosaminidase PF01832.20 EHT99414.1 - 0.038 14.5 0.6 0.1 13.1 0.1 2.2 2 2 0 2 2 2 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Phage_lysozyme2 PF18013.1 EHT99414.1 - 0.065 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Phage tail lysozyme E3_binding PF02817.17 EHT99414.1 - 0.097 13.0 0.3 0.45 10.9 0.0 2.1 2 0 0 2 2 2 0 e3 binding domain HTH_23 PF13384.6 EHT99415.1 - 3.1e-08 33.2 0.0 6e-08 32.3 0.0 1.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 EHT99415.1 - 8.2e-07 29.0 0.2 1.1e-06 28.6 0.2 1.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 EHT99415.1 - 0.00094 19.3 0.1 0.0012 18.9 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHT99415.1 - 0.01 16.4 0.1 0.012 16.1 0.1 1.2 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 HTH_38 PF13936.6 EHT99415.1 - 0.027 14.2 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_32 PF13565.6 EHT99415.1 - 0.044 14.4 0.0 0.07 13.8 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_1 PF01527.20 EHT99416.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT99416.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT99416.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT99416.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHT99417.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein TnpB_IS66 PF05717.13 EHT99418.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHT99419.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT99419.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT99419.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT99419.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix FidL_like PF15941.5 EHT99420.1 - 0.0012 19.2 0.3 0.0057 17.1 0.3 2.0 1 1 0 1 1 1 1 FidL-like putative membrane protein Trans_reg_C PF00486.28 EHT99421.1 - 1.2e-11 44.5 0.0 1.9e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal DUF2270 PF10028.9 EHT99421.1 - 0.18 11.4 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2270) E1-E2_ATPase PF00122.20 EHT99422.1 - 9.9e-42 142.5 0.2 9.9e-42 142.5 0.2 3.1 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 EHT99422.1 - 2.5e-20 73.7 0.1 9.3e-20 71.8 0.1 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 EHT99422.1 - 4.4e-16 59.1 7.6 4.4e-16 59.1 7.6 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 EHT99422.1 - 1.5e-15 56.6 0.0 3.6e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EHT99422.1 - 1.9e-06 27.8 0.0 4.3e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EHT99422.1 - 3.9e-05 23.5 0.0 0.0084 15.9 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EHT99422.1 - 0.017 15.5 0.0 0.053 13.9 0.0 1.9 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase SBP_bac_5 PF00496.22 EHT99423.1 - 3.2e-65 220.6 3.1 4.3e-65 220.1 3.1 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle BPD_transp_1 PF00528.22 EHT99424.1 - 1.9e-39 135.3 14.0 1.9e-39 135.3 14.0 1.5 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 EHT99425.1 - 4.7e-31 108.0 9.0 4.7e-31 108.0 9.0 2.1 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 EHT99425.1 - 4.8e-06 26.4 1.9 4.8e-06 26.4 1.9 3.2 3 0 0 3 3 3 1 N-terminal TM domain of oligopeptide transport permease C Kinocilin PF15033.6 EHT99425.1 - 0.089 12.4 1.1 0.2 11.3 1.1 1.6 1 0 0 1 1 1 0 Kinocilin protein ABC_tran PF00005.27 EHT99426.1 - 4e-22 79.2 0.0 5.8e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EHT99426.1 - 7.6e-07 28.8 0.1 4e-06 26.4 0.1 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EHT99426.1 - 0.00022 21.5 0.4 0.0028 17.9 0.4 2.1 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EHT99426.1 - 0.00098 18.6 0.0 0.0035 16.8 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_21 PF13304.6 EHT99426.1 - 0.002 18.0 0.7 0.076 12.8 0.1 2.1 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 EHT99426.1 - 0.014 15.3 0.8 0.48 10.3 0.0 2.7 2 1 0 3 3 3 0 NACHT domain AAA_16 PF13191.6 EHT99426.1 - 0.019 15.3 0.8 0.064 13.6 0.8 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EHT99426.1 - 0.054 13.2 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EHT99426.1 - 0.059 13.3 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 EHT99426.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region oligo_HPY PF08352.12 EHT99426.1 - 0.14 12.7 0.2 0.26 11.8 0.2 1.5 1 0 0 1 1 1 0 Oligopeptide/dipeptide transporter, C-terminal region CbiA PF01656.23 EHT99426.1 - 0.19 11.8 0.0 0.37 10.9 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF87 PF01935.17 EHT99426.1 - 0.3 11.2 0.1 0.3 11.2 0.1 1.5 2 0 0 2 2 2 0 Helicase HerA, central domain ABC_tran PF00005.27 EHT99427.1 - 4e-32 111.6 0.0 5.1e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EHT99427.1 - 1.2e-12 48.3 4.0 4.9e-09 36.4 0.2 2.8 1 1 2 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EHT99427.1 - 1.7e-05 24.3 0.0 0.00012 21.6 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EHT99427.1 - 2.7e-05 24.6 0.0 4.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EHT99427.1 - 3.2e-05 24.4 0.0 0.11 12.9 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EHT99427.1 - 0.0034 17.4 0.1 2.3 8.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EHT99427.1 - 0.0056 17.0 1.5 0.065 13.5 1.5 2.2 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 EHT99427.1 - 0.0093 15.4 0.1 0.24 10.8 0.0 2.2 2 0 0 2 2 2 1 Bacterial TniB protein RsgA_GTPase PF03193.16 EHT99427.1 - 0.015 15.2 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 EHT99427.1 - 0.052 13.3 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 EHT99427.1 - 0.21 11.9 0.1 2 8.7 0.1 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Acetyltransf_3 PF13302.7 EHT99428.1 - 1.4e-21 77.6 0.1 1.7e-21 77.3 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EHT99428.1 - 3e-15 56.5 0.2 4.3e-15 56.0 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EHT99428.1 - 9.6e-10 38.8 0.3 1.9e-09 37.8 0.3 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EHT99428.1 - 7.8e-08 32.1 0.1 2e-07 30.8 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EHT99428.1 - 3.3e-07 30.6 0.5 4e-07 30.3 0.5 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EHT99428.1 - 4.1e-07 30.0 0.4 5.5e-07 29.6 0.4 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EHT99428.1 - 4e-06 26.7 0.0 7.3e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein GNAT_acetyltran PF12746.7 EHT99428.1 - 0.0042 16.7 0.0 0.0087 15.7 0.0 1.6 1 1 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_CG PF14542.6 EHT99428.1 - 0.013 15.6 0.5 0.076 13.2 0.1 2.2 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase PEGA PF08308.11 EHT99429.1 - 0.0029 17.5 0.0 0.031 14.2 0.0 2.2 1 1 0 1 1 1 1 PEGA domain LPAM_1 PF08139.12 EHT99429.1 - 0.13 12.8 1.0 0.22 12.1 1.0 1.4 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site S-methyl_trans PF02574.16 EHT99430.1 - 1.1e-80 271.4 0.1 1.2e-80 271.2 0.1 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Kelch_1 PF01344.25 EHT99430.1 - 0.013 15.1 0.4 0.1 12.2 0.1 2.5 3 0 0 3 3 3 0 Kelch motif AA_permease PF00324.21 EHT99431.1 - 8.5e-118 394.0 42.0 9.5e-118 393.8 42.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EHT99431.1 - 6.4e-45 153.7 48.6 8.2e-45 153.4 48.6 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4131 PF13567.6 EHT99431.1 - 0.043 13.5 0.5 0.043 13.5 0.5 4.6 4 1 2 6 6 6 0 Domain of unknown function (DUF4131) DUF2002 PF09400.10 EHT99432.1 - 1e-61 205.7 0.2 1.2e-61 205.6 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2002) DUF883 PF05957.13 EHT99433.1 - 1.6e-23 83.1 0.4 1.8e-23 82.9 0.4 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) Nbl1_Borealin_N PF10444.9 EHT99433.1 - 0.0018 17.9 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Apolipoprotein PF01442.18 EHT99433.1 - 0.0095 15.8 0.9 0.01 15.7 0.9 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 EHT99433.1 - 0.025 14.7 0.2 0.026 14.6 0.2 1.1 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) V-ATPase_G PF03179.15 EHT99433.1 - 0.036 14.6 0.1 0.045 14.3 0.1 1.2 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit V-SNARE PF05008.15 EHT99433.1 - 0.06 13.7 0.8 0.079 13.3 0.8 1.2 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus CdiI_2 PF18593.1 EHT99433.1 - 0.069 13.8 0.1 0.084 13.5 0.1 1.2 1 0 0 1 1 1 0 CdiI immunity protein THDPS_N_2 PF14805.6 EHT99433.1 - 0.18 12.1 0.8 0.35 11.1 0.4 1.6 1 1 1 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal YtxH PF12732.7 EHT99433.1 - 0.62 10.6 11.8 3.1 8.4 1.7 2.7 2 1 0 2 2 2 0 YtxH-like protein DivIC PF04977.15 EHT99433.1 - 0.75 9.6 5.2 0.95 9.3 4.6 1.5 1 1 0 1 1 1 0 Septum formation initiator Glutaredoxin PF00462.24 EHT99434.1 - 2e-15 56.7 0.0 2.3e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 EHT99434.1 - 0.00047 20.5 0.0 0.00051 20.4 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N_3 PF13417.6 EHT99434.1 - 0.028 14.8 0.0 0.032 14.7 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_3 PF13192.6 EHT99434.1 - 0.11 12.6 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain Flavodoxin_NdrI PF07972.11 EHT99435.1 - 2.8e-47 159.8 0.0 3.2e-47 159.6 0.0 1.0 1 0 0 1 1 1 1 NrdI Flavodoxin like DUF563 PF04577.14 EHT99435.1 - 0.0011 19.1 0.0 0.0013 18.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Ribonuc_red_sm PF00268.21 EHT99436.1 - 6.7e-86 288.2 0.1 7.7e-86 288.0 0.1 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain MFS_1 PF07690.16 EHT99437.1 - 2.8e-34 118.6 53.2 2.4e-22 79.3 27.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EHT99437.1 - 3.3e-11 42.7 16.9 3.3e-11 42.7 16.9 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 EHT99437.1 - 2.6e-05 23.7 38.9 0.00012 21.5 38.9 1.9 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MarR PF01047.22 EHT99438.1 - 2.3e-15 56.2 1.1 3.6e-15 55.6 0.3 1.7 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.7 EHT99438.1 - 4.4e-10 39.3 0.2 8.6e-10 38.4 0.2 1.5 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 EHT99438.1 - 3.7e-07 30.5 0.4 9.7e-07 29.2 0.1 1.8 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_24 PF13412.6 EHT99438.1 - 2.9e-05 23.5 0.6 9.7e-05 21.9 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 EHT99438.1 - 0.00013 21.9 0.3 0.00028 20.8 0.3 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_34 PF13601.6 EHT99438.1 - 0.0002 21.5 0.0 0.00042 20.4 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 EHT99438.1 - 0.00073 19.3 0.1 0.0013 18.5 0.1 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain TrmB PF01978.19 EHT99438.1 - 0.0031 17.4 0.0 0.0052 16.6 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 EHT99438.1 - 0.0089 16.4 0.2 0.02 15.3 0.0 1.7 2 0 0 2 2 2 1 Transcriptional regulator SgrR_N PF12793.7 EHT99438.1 - 0.027 14.7 0.1 0.056 13.7 0.1 1.7 1 1 0 1 1 1 0 Sugar transport-related sRNA regulator N-term FtsK_gamma PF09397.10 EHT99438.1 - 0.08 12.7 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Ftsk gamma domain AbiEi_4 PF13338.6 EHT99438.1 - 0.11 12.6 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin GntR PF00392.21 EHT99438.1 - 0.17 11.6 1.1 0.28 10.9 0.1 1.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family PadR PF03551.14 EHT99438.1 - 0.2 11.7 0.6 0.3 11.1 0.0 1.6 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family HlyD_D23 PF16576.5 EHT99439.1 - 9.1e-16 57.7 9.9 3.7e-14 52.5 9.9 2.2 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD PF00529.20 EHT99439.1 - 1.1e-14 54.1 0.0 1.9e-14 53.3 0.0 1.4 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS HlyD_3 PF13437.6 EHT99439.1 - 1.2e-11 45.2 4.8 7.2e-11 42.7 0.4 3.1 2 1 1 3 3 3 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 EHT99439.1 - 9.2e-09 35.0 0.9 9.2e-09 35.0 0.9 3.8 4 0 0 4 4 4 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 EHT99439.1 - 0.00029 20.6 0.0 0.87 9.5 0.0 2.4 2 0 0 2 2 2 2 Biotin-requiring enzyme HlyD_2 PF12700.7 EHT99439.1 - 0.013 14.2 3.4 0.056 12.2 3.4 2.0 1 1 0 1 1 1 0 HlyD family secretion protein ydhR PF08803.11 EHT99439.1 - 0.058 13.3 0.3 0.17 11.8 0.2 1.9 2 0 0 2 2 2 0 Putative mono-oxygenase ydhR ECF_trnsprt PF12822.7 EHT99439.1 - 0.12 12.5 0.1 0.2 11.7 0.1 1.2 1 0 0 1 1 1 0 ECF transporter, substrate-specific component DUF848 PF05852.11 EHT99439.1 - 0.17 12.0 3.7 0.34 11.0 3.7 1.5 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) TssO PF17561.2 EHT99439.1 - 0.17 12.0 1.3 23 5.1 0.0 2.4 1 1 1 2 2 2 0 Type VI secretion system, TssO Prefoldin_2 PF01920.20 EHT99439.1 - 0.4 10.7 4.9 0.15 12.0 1.1 2.2 2 1 0 2 2 2 0 Prefoldin subunit DUF4750 PF15938.5 EHT99439.1 - 2.8 7.7 7.4 5 6.9 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4750) OEP PF02321.18 EHT99439.1 - 3.6 7.3 22.0 0.89 9.3 15.8 2.1 1 1 1 2 2 2 0 Outer membrane efflux protein MFS_1 PF07690.16 EHT99440.1 - 1.1e-52 179.2 37.1 1.1e-52 179.2 37.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EHT99440.1 - 6.5e-08 31.9 14.2 6.5e-08 31.9 14.2 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.20 EHT99440.1 - 2.4e-07 29.4 20.5 0.012 13.9 1.2 4.1 3 1 1 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 EHT99440.1 - 0.0062 15.1 5.2 0.0062 15.1 5.2 3.5 4 1 0 4 4 4 2 MFS/sugar transport protein ADH_N PF08240.12 EHT99441.1 - 2e-27 95.2 2.3 2e-27 95.2 2.3 1.9 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EHT99441.1 - 8.4e-21 74.3 0.0 1.6e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EHT99441.1 - 3.1e-07 29.9 0.1 5.1e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 EHT99441.1 - 3.4e-05 24.0 0.0 6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 EHT99441.1 - 7.4e-05 22.2 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 EHT99441.1 - 0.00056 21.0 0.0 0.0011 20.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 3HCDH_N PF02737.18 EHT99441.1 - 0.00096 19.1 0.0 0.005 16.7 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glu_dehyd_C PF16912.5 EHT99441.1 - 0.0016 18.0 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus IGFBP PF00219.18 EHT99441.1 - 0.0054 17.4 1.6 0.01 16.4 0.7 1.9 2 0 0 2 2 1 1 Insulin-like growth factor binding protein Shikimate_DH PF01488.20 EHT99441.1 - 0.041 13.9 0.0 0.089 12.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EHT99441.1 - 0.052 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EHT99441.1 - 0.068 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 EHT99441.1 - 0.083 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 EHT99441.1 - 0.083 13.5 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent HxlR PF01638.17 EHT99442.1 - 6.4e-26 90.0 0.1 8.1e-26 89.7 0.1 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix PadR PF03551.14 EHT99442.1 - 8.8e-05 22.4 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family MarR PF01047.22 EHT99442.1 - 0.0017 18.3 0.1 0.003 17.5 0.1 1.4 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 EHT99442.1 - 0.0067 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 MarR family B-block_TFIIIC PF04182.12 EHT99442.1 - 0.007 16.5 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC DUF4423 PF14394.6 EHT99442.1 - 0.034 13.9 0.0 0.035 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) HTH_20 PF12840.7 EHT99442.1 - 0.1 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_45 PF14947.6 EHT99442.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix SpoU_methylase PF00588.19 EHT99443.1 - 1.8e-31 109.2 0.0 2.6e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 EHT99443.1 - 4.3e-12 46.1 0.0 1.3e-11 44.6 0.0 1.8 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding DTW PF03942.15 EHT99444.1 - 1.8e-43 148.6 0.0 2.2e-43 148.3 0.0 1.0 1 0 0 1 1 1 1 DTW domain ATP-grasp_5 PF13549.6 EHT99445.1 - 8.9e-74 247.7 0.6 1.8e-73 246.7 0.6 1.5 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 EHT99445.1 - 1.1e-43 148.4 0.1 2.9e-43 147.0 0.1 1.8 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EHT99445.1 - 4.9e-21 75.4 0.1 4e-20 72.4 0.0 2.7 3 1 0 3 3 3 1 CoA binding domain Acetyltransf_3 PF13302.7 EHT99445.1 - 8.7e-06 26.5 0.0 2.4e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EHT99445.1 - 0.00012 22.3 0.0 0.00027 21.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family ATP-grasp PF02222.22 EHT99445.1 - 0.0044 16.6 0.1 2.3 7.8 0.0 2.9 3 0 0 3 3 3 2 ATP-grasp domain Acetyltransf_10 PF13673.7 EHT99445.1 - 0.011 15.7 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EHT99445.1 - 0.055 13.6 0.0 19 5.3 0.0 2.6 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain CPSase_L_D2 PF02786.17 EHT99445.1 - 0.11 12.0 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain PLDc_2 PF13091.6 EHT99446.1 - 9e-30 103.3 0.0 1.6e-21 76.6 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EHT99446.1 - 1.6e-11 43.8 0.2 3.5e-06 26.9 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Sld5 PF05916.11 EHT99446.1 - 0.1 13.1 0.2 0.25 11.8 0.2 1.6 1 0 0 1 1 1 0 GINS complex protein Sugar_tr PF00083.24 EHT99447.1 - 5.3e-38 131.0 26.9 2e-24 86.3 9.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EHT99447.1 - 4.3e-27 95.0 36.0 1.1e-17 64.0 16.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EHT99447.1 - 3.1e-09 35.9 22.8 9.2e-05 21.2 8.4 3.4 1 1 2 3 3 3 3 MFS/sugar transport protein MFS_1_like PF12832.7 EHT99447.1 - 2.5e-06 26.6 5.9 9.5e-05 21.4 0.4 3.3 1 1 0 2 2 2 2 MFS_1 like family AzlD PF05437.12 EHT99447.1 - 0.015 15.5 0.6 0.015 15.5 0.6 3.7 3 2 1 4 4 4 0 Branched-chain amino acid transport protein (AzlD) ADH_N PF08240.12 EHT99448.1 - 7.4e-32 109.5 2.1 5.4e-31 106.7 0.6 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EHT99448.1 - 7.1e-31 106.9 1.5 1.1e-30 106.3 1.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EHT99448.1 - 2.5e-05 23.7 1.4 4e-05 23.0 1.4 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EHT99448.1 - 0.00052 19.4 0.2 0.00087 18.7 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 EHT99448.1 - 0.002 19.2 0.0 0.0037 18.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 EHT99448.1 - 0.0028 18.3 0.1 0.0059 17.3 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Urocanase PF01175.18 EHT99448.1 - 0.0029 17.3 1.0 0.0045 16.6 1.0 1.2 1 0 0 1 1 1 1 Urocanase Rossmann-like domain ELFV_dehydrog PF00208.21 EHT99448.1 - 0.0035 17.1 0.4 0.0051 16.6 0.4 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase UDPG_MGDP_dh_N PF03721.14 EHT99448.1 - 0.0051 16.4 0.3 0.0081 15.8 0.3 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_11 PF08241.12 EHT99448.1 - 0.028 15.1 0.1 0.064 13.9 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.18 EHT99448.1 - 0.065 13.5 0.3 0.13 12.5 0.3 1.6 1 0 0 1 1 1 0 TrkA-N domain SIS_2 PF13580.6 EHT99448.1 - 0.12 12.4 1.7 0.23 11.5 1.7 1.4 1 0 0 1 1 1 0 SIS domain AsnC_trans_reg PF01037.21 EHT99449.1 - 1.5e-15 56.9 0.1 2.4e-15 56.3 0.1 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 EHT99449.1 - 1.3e-11 43.9 0.1 1.9e-11 43.3 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 EHT99449.1 - 2.4e-11 43.3 0.7 3.8e-11 42.6 0.7 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain MarR PF01047.22 EHT99449.1 - 0.0005 19.9 0.1 0.0008 19.3 0.1 1.3 1 0 0 1 1 1 1 MarR family HTH_11 PF08279.12 EHT99449.1 - 0.0014 18.5 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 HTH domain HTH_20 PF12840.7 EHT99449.1 - 0.022 14.8 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain PheRS_DBD1 PF18552.1 EHT99449.1 - 0.064 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 PheRS DNA binding domain 1 Fe_dep_repress PF01325.19 EHT99449.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_1 PF00126.27 EHT99449.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family PadR PF03551.14 EHT99449.1 - 0.12 12.4 0.0 0.35 10.8 0.0 1.7 1 1 1 2 2 2 0 Transcriptional regulator PadR-like family HTH_Tnp_1 PF01527.20 EHT99450.1 - 2.6e-15 56.5 0.0 1.6e-14 53.9 0.0 2.2 2 1 0 2 2 2 1 Transposase HTH_23 PF13384.6 EHT99450.1 - 1.4e-06 27.9 0.0 0.017 14.9 0.0 2.3 2 0 0 2 2 2 2 Homeodomain-like domain HTH_28 PF13518.6 EHT99450.1 - 0.0034 17.5 0.0 0.66 10.2 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain MarR_2 PF12802.7 EHT99450.1 - 0.054 13.4 0.1 0.68 9.9 0.0 2.3 2 0 0 2 2 2 0 MarR family LZ_Tnp_IS481 PF13011.6 EHT99450.1 - 0.084 13.4 0.2 3.4 8.3 0.0 2.6 3 0 0 3 3 3 0 leucine-zipper of insertion element IS481 TnpB_IS66 PF05717.13 EHT99451.1 - 2.7e-05 24.0 0.0 2.9e-05 23.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein LZ_Tnp_IS66 PF13007.7 EHT99452.1 - 1.3e-06 29.0 0.4 1.3e-06 29.0 0.4 1.6 2 0 0 2 2 2 1 Transposase C of IS166 homeodomain Troponin PF00992.20 EHT99452.1 - 0.0004 20.7 0.9 0.00047 20.5 0.9 1.0 1 0 0 1 1 1 1 Troponin Shugoshin_N PF07558.11 EHT99452.1 - 0.0017 18.2 1.7 0.0041 17.0 0.2 2.3 1 1 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Csm1_N PF18504.1 EHT99452.1 - 0.0038 17.5 3.3 0.0056 17.0 0.9 2.1 1 1 1 2 2 2 1 Csm1 N-terminal domain FUSC PF04632.12 EHT99452.1 - 0.0047 15.5 3.8 0.0048 15.5 3.8 1.0 1 0 0 1 1 1 1 Fusaric acid resistance protein family LXG PF04740.12 EHT99452.1 - 0.013 15.2 0.5 0.017 14.9 0.5 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily Tricho_coat PF05892.11 EHT99452.1 - 0.052 13.3 0.1 0.076 12.8 0.1 1.4 1 1 0 1 1 1 0 Trichovirus coat protein ERM PF00769.19 EHT99452.1 - 0.056 13.3 5.7 0.063 13.1 5.7 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family NRBF2 PF08961.10 EHT99452.1 - 0.061 12.9 1.0 0.071 12.7 1.0 1.2 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator USP8_interact PF08941.10 EHT99452.1 - 0.077 12.8 2.4 0.085 12.7 2.4 1.1 1 0 0 1 1 1 0 USP8 interacting CLP_protease PF00574.23 EHT99452.1 - 0.11 12.4 0.5 0.12 12.3 0.5 1.0 1 0 0 1 1 1 0 Clp protease DUF1192 PF06698.11 EHT99452.1 - 0.12 12.5 0.2 0.12 12.5 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) NYD-SP28_assoc PF14775.6 EHT99452.1 - 0.27 11.4 4.1 1.3 9.2 1.0 2.3 2 0 0 2 2 2 0 Sperm tail C-terminal domain MerR-DNA-bind PF09278.11 EHT99452.1 - 0.34 11.5 7.7 2.8 8.5 3.8 2.3 2 1 0 2 2 2 0 MerR, DNA binding SlyX PF04102.12 EHT99452.1 - 0.6 10.8 6.3 5.8 7.6 6.3 2.3 1 1 0 1 1 1 0 SlyX DUF1173 PF06666.11 EHT99454.1 - 5.5e-44 150.6 0.0 6.2e-44 150.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1173) DUF790 PF05626.11 EHT99454.1 - 0.0064 15.3 0.1 0.008 14.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF790) BB_PF PF18063.1 EHT99455.1 - 0.057 13.0 2.4 0.082 12.5 2.4 1.2 1 0 0 1 1 1 0 Beta barrel Pore-forming domain Phage_sheath_1C PF17482.2 EHT99455.1 - 0.094 12.7 0.1 0.21 11.6 0.0 1.6 2 0 0 2 2 2 0 Phage tail sheath C-terminal domain Resolvase PF00239.21 EHT99456.1 - 2.3e-23 82.9 1.9 5.6e-23 81.7 1.9 1.6 1 1 0 1 1 1 1 Resolvase, N terminal domain HTH_7 PF02796.15 EHT99456.1 - 2.6e-07 30.6 0.3 7.1e-07 29.2 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 EHT99456.1 - 0.0035 17.1 0.2 0.0084 15.9 0.2 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_35 PF13693.6 EHT99456.1 - 0.078 13.0 0.3 0.32 11.0 0.2 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding SopA_C PF13979.6 EHT99460.1 - 2.5e-36 125.0 0.0 6.9e-36 123.5 0.0 1.7 1 0 0 1 1 1 1 SopA-like catalytic domain Pentapeptide PF00805.22 EHT99460.1 - 3.3e-06 26.6 2.8 0.00092 18.8 0.1 3.2 3 0 0 3 3 3 2 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 EHT99460.1 - 0.00042 20.4 0.6 0.0022 18.1 0.6 2.3 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) SopA PF13981.6 EHT99460.1 - 0.0014 19.1 0.7 0.0014 19.1 0.7 2.0 2 0 0 2 2 2 1 SopA-like central domain Pentapeptide_3 PF13576.6 EHT99460.1 - 0.013 15.7 6.4 0.28 11.4 7.0 2.8 1 1 1 2 2 2 0 Pentapeptide repeats (9 copies) PI_PP_C PF18365.1 EHT99460.1 - 0.015 15.2 0.4 0.04 13.9 0.1 1.9 2 0 0 2 2 2 0 Phosphoinositide phosphatase C-terminal domain DDE_3 PF13358.6 EHT99461.1 - 1.7e-12 47.3 1.8 2.1e-12 47.0 1.8 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Sif PF06767.11 EHT99462.1 - 1.7e-25 89.7 5.2 2.2e-25 89.4 5.2 1.1 1 0 0 1 1 1 1 Sif protein IpaB_EvcA PF03278.13 EHT99462.1 - 2.1e-21 76.2 8.2 5e-21 75.0 8.2 1.6 1 0 0 1 1 1 1 IpaB/EvcA family Glyoxalase_2 PF12681.7 EHT99462.1 - 0.063 13.2 5.0 0.14 12.1 0.7 2.4 2 0 0 2 2 2 0 Glyoxalase-like domain MA3 PF02847.17 EHT99462.1 - 0.076 13.0 2.4 0.13 12.3 0.1 2.5 3 0 0 3 3 3 0 MA3 domain HTH_Tnp_1 PF01527.20 EHT99463.1 - 3e-11 43.5 0.2 3.9e-11 43.1 0.2 1.2 1 0 0 1 1 1 1 Transposase LZ_Tnp_IS481 PF13011.6 EHT99463.1 - 0.002 18.6 0.1 0.0032 18.0 0.1 1.4 1 1 0 1 1 1 1 leucine-zipper of insertion element IS481 HTH_28 PF13518.6 EHT99463.1 - 0.0045 17.1 0.0 0.0075 16.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 EHT99463.1 - 0.019 15.0 0.0 0.034 14.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix MarR PF01047.22 EHT99463.1 - 0.02 14.8 0.0 0.054 13.4 0.0 1.7 2 0 0 2 2 2 0 MarR family TSC22 PF01166.18 EHT99463.1 - 0.037 14.3 1.1 0.065 13.6 1.1 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family ResIII PF04851.15 EHT99464.1 - 1.9e-18 67.1 0.0 3e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EHT99464.1 - 1.5e-06 28.1 0.0 2.9e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EHT99464.1 - 1.8e-06 28.3 0.0 4.2e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DNA_primase_S PF01896.19 EHT99464.1 - 5e-05 23.4 0.0 0.00015 21.8 0.0 1.7 1 1 0 1 1 1 1 DNA primase small subunit SNF2_N PF00176.23 EHT99464.1 - 0.00011 21.0 0.0 0.00024 20.0 0.0 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain SWI2_SNF2 PF18766.1 EHT99464.1 - 0.013 15.2 0.0 0.045 13.4 0.0 1.8 2 0 0 2 2 2 0 SWI2/SNF2 ATPase Resolvase PF00239.21 EHT99465.1 - 9.1e-47 158.8 1.0 1.3e-46 158.4 1.0 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_32 PF13565.6 EHT99465.1 - 0.0002 21.9 5.1 0.00068 20.2 0.7 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 EHT99465.1 - 0.00024 21.1 1.4 0.0029 17.6 0.0 2.3 1 1 1 2 2 2 1 Winged helix-turn helix HTH_38 PF13936.6 EHT99465.1 - 0.00057 19.6 0.1 0.002 17.8 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 EHT99465.1 - 0.00083 18.7 0.1 0.002 17.5 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.6 EHT99465.1 - 0.0024 17.9 0.1 0.0056 16.8 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_7 PF02796.15 EHT99465.1 - 0.011 15.8 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 EHT99465.1 - 0.04 13.7 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_17 PF12728.7 EHT99465.1 - 0.062 13.5 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 EHT99465.1 - 0.093 12.4 0.6 0.37 10.5 0.0 2.1 2 1 0 2 2 2 0 Sigma-70, region 4 FliT PF05400.13 EHT99465.1 - 0.23 12.3 4.5 0.11 13.3 1.3 2.0 2 1 0 2 2 2 0 Flagellar protein FliT HTH_33 PF13592.6 EHT99465.1 - 0.31 10.7 1.8 12 5.6 0.0 2.7 3 0 0 3 3 3 0 Winged helix-turn helix FUSC-like PF12805.7 EHT99466.1 - 4.1e-41 140.9 0.7 4.6e-41 140.8 0.7 1.0 1 0 0 1 1 1 1 FUSC-like inner membrane protein yccS cNMP_binding PF00027.29 EHT99468.1 - 3.4e-24 84.7 0.0 5.4e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 EHT99468.1 - 4.3e-14 52.2 0.1 2.2e-13 50.0 0.0 2.0 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain Crp PF00325.20 EHT99468.1 - 5e-09 35.7 0.1 9.2e-09 34.8 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, crp family MarR_2 PF12802.7 EHT99468.1 - 0.00016 21.5 0.0 0.0012 18.7 0.0 2.1 2 0 0 2 2 2 1 MarR family HTH_23 PF13384.6 EHT99468.1 - 0.00053 19.7 0.0 0.0014 18.4 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain RepL PF05732.11 EHT99468.1 - 0.0011 18.5 0.1 0.16 11.4 0.1 2.3 2 0 0 2 2 2 1 Firmicute plasmid replication protein (RepL) HTH_36 PF13730.6 EHT99468.1 - 0.0014 18.6 0.0 0.0068 16.3 0.0 2.1 3 0 0 3 3 3 1 Helix-turn-helix domain MarR PF01047.22 EHT99468.1 - 0.0074 16.2 0.1 0.029 14.3 0.1 1.9 2 0 0 2 2 2 1 MarR family HTH_24 PF13412.6 EHT99468.1 - 0.0088 15.6 0.2 0.023 14.2 0.2 1.8 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 EHT99468.1 - 0.021 14.4 0.8 0.057 12.9 0.2 2.0 3 0 0 3 3 3 0 Sigma-70, region 4 HTH_7 PF02796.15 EHT99468.1 - 0.057 13.5 0.1 0.23 11.5 0.1 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Rrf2 PF02082.20 EHT99468.1 - 0.091 13.1 0.2 0.85 10.0 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulator HhH-GPD PF00730.25 EHT99468.1 - 0.1 13.1 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein HTH_11 PF08279.12 EHT99468.1 - 0.11 12.5 0.4 0.24 11.4 0.1 1.8 2 0 0 2 2 2 0 HTH domain HTH_38 PF13936.6 EHT99468.1 - 0.12 12.1 0.1 0.47 10.2 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain DUF4868 PF16162.5 EHT99468.1 - 0.13 12.2 0.0 0.31 10.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4868) RPA_C PF08784.11 EHT99468.1 - 0.14 12.8 0.1 0.29 11.8 0.1 1.5 1 0 0 1 1 1 0 Replication protein A C terminal OsmC PF02566.19 EHT99469.1 - 2e-18 66.7 0.0 2.6e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 OsmC-like protein PRK PF00485.18 EHT99470.1 - 3e-74 249.0 0.0 3.6e-74 248.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.20 EHT99470.1 - 0.014 15.3 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase UPF0270 PF06794.12 EHT99471.1 - 2.4e-35 120.4 0.3 2.6e-35 120.3 0.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0270) Abhydrolase_1 PF00561.20 EHT99472.1 - 4.1e-13 49.6 0.1 7.4e-13 48.7 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EHT99472.1 - 3.2e-08 33.1 0.0 4.9e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EHT99472.1 - 0.23 10.9 0.7 9.7 5.6 0.0 2.4 2 1 0 2 2 2 0 Prolyl oligopeptidase family LysE PF01810.18 EHT99473.1 - 3.5e-16 59.2 17.7 4.5e-16 58.9 17.7 1.1 1 0 0 1 1 1 1 LysE type translocator Peripla_BP_3 PF13377.6 EHT99474.1 - 4.5e-34 118.2 0.0 6.5e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 EHT99474.1 - 1.2e-22 80.7 0.0 1.7e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 EHT99474.1 - 3.3e-17 62.0 0.1 7.7e-17 60.8 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 EHT99474.1 - 1.6e-12 47.6 0.0 3.4e-12 46.5 0.0 1.6 1 1 0 1 1 1 1 Periplasmic binding protein domain HTH_3 PF01381.22 EHT99474.1 - 0.017 15.2 0.0 0.04 14.0 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix HTH_31 PF13560.6 EHT99474.1 - 0.024 15.0 0.6 0.078 13.3 0.0 2.3 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_7 PF02796.15 EHT99474.1 - 0.066 13.3 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase ClpB_D2-small PF10431.9 EHT99474.1 - 0.069 13.2 0.0 0.26 11.4 0.0 1.9 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein OpuAC PF04069.12 EHT99475.1 - 6.6e-23 81.6 0.9 1e-22 80.9 0.9 1.3 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system NMT1_2 PF13379.6 EHT99475.1 - 7.5e-22 78.2 2.8 2.4e-21 76.6 2.8 1.7 1 1 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 EHT99475.1 - 1.3e-19 71.1 0.0 1.8e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 EHT99475.1 - 4.2e-08 33.1 0.2 6.9e-08 32.4 0.2 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 EHT99475.1 - 0.00046 19.7 0.1 0.0061 16.0 0.0 2.5 2 1 1 3 3 3 2 Bacterial extracellular solute-binding proteins, family 3 VitK2_biosynth PF02621.14 EHT99475.1 - 0.0065 16.0 0.0 2.2 7.7 0.0 2.2 2 0 0 2 2 2 2 Menaquinone biosynthesis ABC_tran PF00005.27 EHT99476.1 - 3.4e-29 102.1 0.0 4.7e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EHT99476.1 - 1.1e-07 32.0 0.2 0.0096 15.8 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EHT99476.1 - 5.3e-06 26.7 0.0 2.7e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EHT99476.1 - 9e-05 22.4 0.0 0.00015 21.7 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EHT99476.1 - 0.00018 22.0 0.2 0.00029 21.3 0.2 1.4 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 EHT99476.1 - 0.00041 20.3 0.0 0.011 15.7 0.0 2.5 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_28 PF13521.6 EHT99476.1 - 0.0015 18.8 0.7 0.032 14.5 0.2 2.5 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 EHT99476.1 - 0.0016 18.9 0.0 0.007 16.8 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 EHT99476.1 - 0.002 17.6 0.1 0.75 9.2 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain NACHT PF05729.12 EHT99476.1 - 0.0027 17.6 0.8 0.031 14.2 0.1 2.2 2 1 0 2 2 2 1 NACHT domain AAA_23 PF13476.6 EHT99476.1 - 0.0032 18.0 0.0 0.0051 17.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 EHT99476.1 - 0.0052 17.0 0.5 0.098 12.9 0.5 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 EHT99476.1 - 0.0055 16.4 0.0 0.011 15.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 EHT99476.1 - 0.0069 15.5 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Rad17 PF03215.15 EHT99476.1 - 0.0081 16.1 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_33 PF13671.6 EHT99476.1 - 0.01 16.0 0.0 0.027 14.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EHT99476.1 - 0.013 15.2 0.2 0.04 13.6 0.2 1.8 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EHT99476.1 - 0.015 14.8 0.0 0.26 10.7 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_15 PF13175.6 EHT99476.1 - 0.019 14.7 0.0 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.21 EHT99476.1 - 0.071 12.5 0.0 0.27 10.6 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 EHT99476.1 - 0.072 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 EHT99476.1 - 0.075 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EHT99476.1 - 0.077 13.0 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EHT99476.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EHT99476.1 - 0.17 12.3 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 EHT99476.1 - 0.21 11.9 0.1 0.75 10.1 0.0 1.9 2 1 1 3 3 2 0 AAA domain NB-ARC PF00931.22 EHT99476.1 - 0.22 10.7 0.0 0.61 9.2 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain BPD_transp_1 PF00528.22 EHT99477.1 - 2e-22 79.8 13.9 2e-22 79.8 13.9 2.1 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component TauD PF02668.16 EHT99478.1 - 3.1e-64 217.4 3.0 3.5e-64 217.2 3.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF3746 PF12562.8 EHT99478.1 - 0.096 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3746) ABC_tran PF00005.27 EHT99479.1 - 6.6e-50 169.2 6.6 1.9e-24 86.7 0.0 3.8 4 0 0 4 4 4 2 ABC transporter ABC_tran_Xtn PF12848.7 EHT99479.1 - 3.6e-28 97.4 5.5 3.6e-28 97.4 5.5 3.2 2 1 1 3 3 2 1 ABC transporter AAA_21 PF13304.6 EHT99479.1 - 6.7e-16 59.0 14.2 0.00067 19.6 0.1 4.4 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EHT99479.1 - 1e-08 34.9 1.9 0.077 12.4 0.0 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EHT99479.1 - 4.1e-07 30.1 1.0 0.0077 16.2 0.1 2.9 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EHT99479.1 - 5.5e-07 29.7 2.6 0.0049 16.9 0.0 3.3 3 1 0 3 3 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EHT99479.1 - 7.5e-06 25.6 2.1 0.055 13.2 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_tran_CTD PF16326.5 EHT99479.1 - 1.8e-05 24.9 12.2 1.8e-05 24.9 12.2 4.2 3 1 1 4 4 4 1 ABC transporter C-terminal domain KAP_NTPase PF07693.14 EHT99479.1 - 4.5e-05 22.8 1.6 0.071 12.3 0.1 2.8 2 2 0 3 3 3 2 KAP family P-loop domain AAA_18 PF13238.6 EHT99479.1 - 8.8e-05 23.1 2.8 0.58 10.7 0.0 3.7 4 1 0 4 4 3 2 AAA domain AAA_16 PF13191.6 EHT99479.1 - 0.00015 22.2 11.3 0.019 15.3 0.2 3.4 2 2 1 3 3 3 2 AAA ATPase domain RNA_helicase PF00910.22 EHT99479.1 - 0.00055 20.3 0.4 1.3 9.5 0.1 2.5 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.12 EHT99479.1 - 0.00078 19.4 3.4 1.7 8.6 0.1 3.4 3 0 0 3 3 3 2 NACHT domain AAA PF00004.29 EHT99479.1 - 0.0017 18.7 0.1 1 9.8 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.25 EHT99479.1 - 0.0025 17.5 0.2 0.32 10.6 0.0 2.6 3 0 0 3 3 2 1 ATP synthase alpha/beta family, nucleotide-binding domain MeaB PF03308.16 EHT99479.1 - 0.0036 16.3 9.6 0.097 11.6 0.2 3.1 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF815 PF05673.13 EHT99479.1 - 0.0067 15.6 2.6 2.1 7.4 0.5 3.2 2 1 1 3 3 3 1 Protein of unknown function (DUF815) NB-ARC PF00931.22 EHT99479.1 - 0.0079 15.4 0.1 1 8.5 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain AAA_28 PF13521.6 EHT99479.1 - 0.021 15.1 3.1 5.1 7.3 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 EHT99479.1 - 0.026 14.1 8.1 0.32 10.5 0.0 3.9 4 1 0 4 4 4 0 AAA domain MobB PF03205.14 EHT99479.1 - 0.032 14.1 2.0 1.9 8.4 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.12 EHT99479.1 - 0.041 13.2 5.1 1.8 7.8 0.1 2.9 3 0 0 3 3 3 0 Zeta toxin SbcCD_C PF13558.6 EHT99479.1 - 0.057 13.6 1.7 2 8.7 0.1 3.9 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit Roc PF08477.13 EHT99479.1 - 0.065 13.5 1.4 13 6.0 0.1 3.2 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 EHT99479.1 - 0.066 13.1 0.2 15 5.4 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain NTPase_1 PF03266.15 EHT99479.1 - 0.067 13.1 1.0 5.9 6.8 0.1 2.7 2 0 0 2 2 2 0 NTPase AAA_15 PF13175.6 EHT99479.1 - 0.074 12.7 0.3 0.074 12.7 0.3 4.4 4 1 0 5 5 5 0 AAA ATPase domain FeoB_N PF02421.18 EHT99479.1 - 0.13 11.8 0.3 4.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_24 PF13479.6 EHT99479.1 - 0.14 11.8 6.1 4.4 7.0 0.1 3.3 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.9 EHT99479.1 - 0.16 11.7 4.2 4.1 7.2 0.3 2.8 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 EHT99479.1 - 0.17 12.2 7.9 1.5 9.1 0.0 3.8 4 0 0 4 4 4 0 AAA domain AAA_23 PF13476.6 EHT99479.1 - 0.17 12.3 0.2 0.17 12.3 0.2 4.0 3 1 0 3 3 3 0 AAA domain DUF1192 PF06698.11 EHT99479.1 - 0.26 11.4 8.9 0.91 9.6 2.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) NAD_binding_9 PF13454.6 EHT99479.1 - 0.33 11.0 6.2 0.072 13.1 1.2 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding TsaE PF02367.17 EHT99479.1 - 0.37 10.8 1.6 5.7 7.0 0.2 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 EHT99479.1 - 0.94 9.5 5.1 7.7 6.5 0.1 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EHT99479.1 - 2.7 8.1 10.4 7 6.8 0.0 3.9 4 0 0 4 4 4 0 AAA domain DUF87 PF01935.17 EHT99479.1 - 4.4 7.3 16.0 0.21 11.7 0.4 3.9 4 0 0 4 4 4 0 Helicase HerA, central domain Exonuc_VII_L PF02601.15 EHT99479.1 - 4.9 6.6 11.8 6.1 6.3 0.3 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit APG6_N PF17675.1 EHT99479.1 - 6 7.4 29.0 0.25 11.9 17.8 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region Flavodoxin_2 PF02525.17 EHT99480.1 - 5e-41 140.6 0.0 5.8e-41 140.4 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 EHT99480.1 - 4.6e-05 23.2 0.0 6.6e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Hepar_II_III_N PF16889.5 EHT99480.1 - 0.00084 18.7 0.2 0.0012 18.3 0.2 1.2 1 0 0 1 1 1 1 Heparinase II/III N-terminus Na_H_Exchanger PF00999.21 EHT99481.1 - 2.7e-68 230.5 45.4 3.9e-68 230.0 45.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 EHT99481.1 - 3.9e-26 91.6 0.1 6.7e-26 90.8 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 EHT99481.1 - 0.00043 20.5 0.0 0.00076 19.7 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EHT99481.1 - 0.0071 16.4 0.1 0.036 14.1 0.1 2.1 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 EHT99481.1 - 0.074 12.3 0.2 0.099 11.9 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain DUF4781 PF16013.5 EHT99481.1 - 4.4 6.0 5.5 1.8 7.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4781) DUF2387 PF09526.10 EHT99482.1 - 3.1e-20 72.1 1.9 3.5e-20 71.9 1.9 1.1 1 0 0 1 1 1 1 Probable metal-binding protein (DUF2387) Zn_Tnp_IS1595 PF12760.7 EHT99482.1 - 3e-05 23.9 0.7 4.5e-05 23.3 0.7 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Lar_restr_allev PF14354.6 EHT99482.1 - 0.00013 22.2 1.2 0.00017 21.9 1.2 1.1 1 0 0 1 1 1 1 Restriction alleviation protein Lar GATA PF00320.27 EHT99482.1 - 0.00047 19.7 0.5 0.00071 19.1 0.5 1.3 1 0 0 1 1 1 1 GATA zinc finger eIF-5_eIF-2B PF01873.17 EHT99482.1 - 0.003 17.4 0.6 0.0039 17.0 0.6 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 zf-ribbon_3 PF13248.6 EHT99482.1 - 0.0039 16.6 1.7 1.3 8.6 0.1 2.2 2 0 0 2 2 2 2 zinc-ribbon domain Elf1 PF05129.13 EHT99482.1 - 0.0098 15.9 0.5 0.011 15.8 0.5 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like OrfB_Zn_ribbon PF07282.11 EHT99482.1 - 0.031 14.2 0.9 0.04 13.8 0.9 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-Mss51 PF13824.6 EHT99482.1 - 0.031 14.4 0.5 0.037 14.1 0.5 1.2 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 UPF0547 PF10571.9 EHT99482.1 - 0.059 13.5 2.9 6.3 7.0 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 TFIIS_C PF01096.18 EHT99482.1 - 0.064 13.1 4.4 1.6 8.7 0.6 2.7 2 1 1 3 3 3 0 Transcription factor S-II (TFIIS) zinc_ribbon_2 PF13240.6 EHT99482.1 - 0.066 12.9 2.9 2 8.3 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 EHT99482.1 - 0.067 13.2 2.8 0.2 11.7 2.7 1.7 1 1 0 1 1 1 0 Double zinc ribbon Rubredoxin_2 PF18073.1 EHT99482.1 - 0.11 12.2 2.4 5.4 6.8 0.1 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain zinc_ribbon_4 PF13717.6 EHT99482.1 - 0.12 12.3 4.5 0.5 10.3 4.5 1.9 1 1 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 EHT99482.1 - 0.62 10.2 5.2 9.4 6.4 0.6 2.1 1 1 0 2 2 2 0 Zinc ribbon domain FKBP_C PF00254.28 EHT99483.1 - 4.8e-10 39.6 0.0 6.5e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase UreE_C PF05194.12 EHT99483.1 - 0.071 13.6 9.9 0.15 12.6 9.9 1.5 1 0 0 1 1 1 0 UreE urease accessory protein, C-terminal domain SlyX PF04102.12 EHT99484.1 - 1.3e-23 83.4 1.1 1.4e-23 83.2 1.1 1.0 1 0 0 1 1 1 1 SlyX CEP63 PF17045.5 EHT99484.1 - 0.0065 16.4 1.3 0.0067 16.4 1.3 1.1 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa DUF641 PF04859.12 EHT99484.1 - 0.02 15.2 2.2 0.023 15.1 2.2 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF16 PF01519.16 EHT99484.1 - 0.061 13.8 0.8 0.071 13.6 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF16 Fib_alpha PF08702.10 EHT99484.1 - 0.099 12.8 1.0 0.11 12.7 1.0 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family FKBP_C PF00254.28 EHT99485.1 - 6.7e-31 106.5 0.3 4.2e-28 97.5 0.0 2.5 2 1 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.18 EHT99485.1 - 1.1e-23 83.9 8.4 2.4e-23 82.9 8.4 1.5 1 0 0 1 1 1 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase YbgS PF13985.6 EHT99485.1 - 0.0023 18.2 2.2 0.0023 18.2 2.2 1.9 2 1 0 2 2 2 1 YbgS-like protein Stathmin PF00836.19 EHT99485.1 - 0.019 14.9 2.6 0.041 13.8 2.6 1.5 1 0 0 1 1 1 0 Stathmin family DUF4827 PF16109.5 EHT99485.1 - 0.077 13.0 0.1 0.73 9.8 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4827) PAS_6 PF08348.11 EHT99486.1 - 8.5e-37 125.5 0.1 1.6e-36 124.6 0.1 1.4 1 0 0 1 1 1 1 YheO-like PAS domain HTH_22 PF13309.6 EHT99486.1 - 5.2e-19 68.1 0.5 8.8e-19 67.4 0.5 1.4 1 0 0 1 1 1 1 HTH domain HTH_23 PF13384.6 EHT99486.1 - 1.8e-05 24.4 0.0 4.9e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.15 EHT99486.1 - 0.00012 22.1 0.1 0.00053 20.0 0.1 2.2 2 1 0 2 2 2 1 Helix-turn-helix domain of resolvase DUF658 PF04936.12 EHT99486.1 - 0.0012 18.6 0.1 0.0021 17.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF658) HTH_17 PF12728.7 EHT99486.1 - 0.0018 18.4 0.0 0.0046 17.1 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain dCache_1 PF02743.18 EHT99486.1 - 0.0019 18.0 0.0 0.0043 16.9 0.0 1.4 1 1 0 1 1 1 1 Cache domain HTH_10 PF04967.12 EHT99486.1 - 0.013 15.3 0.1 0.029 14.1 0.1 1.6 1 0 0 1 1 1 0 HTH DNA binding domain HTH_29 PF13551.6 EHT99486.1 - 0.022 14.8 0.0 0.059 13.4 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix HTH_28 PF13518.6 EHT99486.1 - 0.032 14.4 0.0 0.067 13.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain MerR PF00376.23 EHT99486.1 - 0.064 13.0 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 MerR family regulatory protein GerE PF00196.19 EHT99486.1 - 0.094 12.3 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family NUMOD1 PF07453.13 EHT99486.1 - 0.24 11.7 0.8 1.5 9.2 0.1 2.4 3 0 0 3 3 2 0 NUMOD1 domain DrsE PF02635.15 EHT99487.1 - 4e-28 98.1 0.1 4.5e-28 98.0 0.1 1.0 1 0 0 1 1 1 1 DsrE/DsrF-like family DrsE PF02635.15 EHT99488.1 - 4e-25 88.5 0.0 4.4e-25 88.3 0.0 1.0 1 0 0 1 1 1 1 DsrE/DsrF-like family DsrH PF04077.12 EHT99489.1 - 2.4e-27 94.9 0.1 2.7e-27 94.7 0.1 1.0 1 0 0 1 1 1 1 DsrH like protein Ribosom_S12_S23 PF00164.25 EHT99490.1 - 1.1e-42 144.2 1.3 1.3e-42 144.0 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S12 PF17487.2 EHT99490.1 - 0.1 13.4 0.0 0.19 12.5 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein S12 Ribosomal_S7 PF00177.21 EHT99491.1 - 1.3e-65 219.6 2.4 1.4e-65 219.5 2.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e GTP_EFTU PF00009.27 EHT99492.1 - 1.8e-66 223.4 0.1 2.7e-66 222.8 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EHT99492.1 - 2.8e-45 153.0 0.0 6.2e-45 151.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 EHT99492.1 - 4.2e-34 116.5 0.0 9.6e-34 115.3 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EHT99492.1 - 3.2e-29 100.8 0.0 8.2e-29 99.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EHT99492.1 - 7.5e-17 61.5 0.1 2.1e-16 60.1 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EHT99492.1 - 1.4e-06 28.1 0.1 4.6e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain GTP_EFTU PF00009.27 EHT99493.1 - 6.2e-59 198.8 0.0 8.8e-59 198.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EHT99493.1 - 1e-33 116.0 0.0 2e-33 115.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EHT99493.1 - 2.1e-19 69.7 4.7 4.6e-19 68.6 4.7 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EHT99493.1 - 9.9e-05 22.4 0.0 0.0002 21.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 EHT99493.1 - 0.034 13.8 0.2 0.094 12.3 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Lsm_C PF14894.6 EHT99493.1 - 0.37 10.6 2.5 0.83 9.5 2.5 1.5 1 0 0 1 1 1 0 Lsm C-terminal Fer2_BFD PF04324.15 EHT99494.1 - 9.7e-13 48.3 0.9 1.2e-12 48.0 0.9 1.1 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain HRDC PF00570.23 EHT99494.1 - 0.00097 19.1 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 HRDC domain Ferritin PF00210.24 EHT99495.1 - 8.1e-38 129.5 4.4 1.1e-37 129.1 4.4 1.2 1 0 0 1 1 1 1 Ferritin-like domain DUF1241 PF06840.11 EHT99495.1 - 0.0041 16.8 0.1 0.0071 16.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) DiS_P_DiS PF06750.13 EHT99496.1 - 7.7e-21 74.0 2.0 1.4e-20 73.2 2.0 1.4 1 0 0 1 1 1 1 Bacterial Peptidase A24 N-terminal domain Peptidase_A24 PF01478.18 EHT99496.1 - 6e-19 68.4 9.7 6e-19 68.4 9.7 2.1 2 0 0 2 2 2 1 Type IV leader peptidase family Ribosomal_S10 PF00338.22 EHT99497.1 - 2.1e-35 120.9 0.1 2.3e-35 120.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Ribosomal_L3 PF00297.22 EHT99498.1 - 2.4e-14 53.1 2.9 2.4e-14 53.1 2.9 2.7 1 1 2 3 3 3 2 Ribosomal protein L3 Ribosomal_L4 PF00573.22 EHT99499.1 - 2e-63 213.5 1.0 2.3e-63 213.4 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_L23 PF00276.20 EHT99500.1 - 6.2e-31 106.6 3.8 7.1e-31 106.4 3.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L23 Ribosomal_L2_C PF03947.18 EHT99501.1 - 4.3e-55 185.3 3.8 6.9e-55 184.6 3.8 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EHT99501.1 - 1.9e-34 117.5 1.1 8.6e-34 115.3 0.6 2.1 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_S19 PF00203.21 EHT99502.1 - 1.3e-35 121.1 0.0 1.5e-35 120.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_L22 PF00237.19 EHT99503.1 - 2.7e-34 117.5 2.0 3e-34 117.4 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_S3_C PF00189.20 EHT99504.1 - 1.1e-41 141.2 0.9 2.1e-41 140.3 0.9 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 EHT99504.1 - 1.5e-19 69.6 3.9 3.4e-19 68.4 3.9 1.6 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 EHT99504.1 - 2.9e-05 23.8 0.3 6e-05 22.8 0.3 1.5 1 0 0 1 1 1 1 KH domain Ribosomal_L16 PF00252.18 EHT99505.1 - 5e-47 159.2 0.6 5.6e-47 159.0 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF982 PF06169.12 EHT99505.1 - 0.29 11.2 1.8 9 6.4 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF982) Ribosomal_L29 PF00831.23 EHT99506.1 - 1.7e-22 79.1 6.8 1.9e-22 79.0 6.8 1.0 1 0 0 1 1 1 1 Ribosomal L29 protein MRP-L47 PF06984.13 EHT99506.1 - 0.00023 21.2 2.5 0.00028 20.9 2.5 1.1 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) YjcZ PF13990.6 EHT99506.1 - 0.048 13.0 0.6 0.045 13.1 0.6 1.0 1 0 0 1 1 1 0 YjcZ-like protein PRTP PF01366.18 EHT99506.1 - 0.12 10.4 1.4 0.12 10.3 1.4 1.0 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Ribosomal_S17 PF00366.20 EHT99507.1 - 2.2e-34 117.4 0.8 2.5e-34 117.2 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_L14 PF00238.19 EHT99508.1 - 3.7e-55 185.2 1.0 4.1e-55 185.1 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Gp58 PF07902.11 EHT99508.1 - 0.062 11.6 0.0 0.071 11.4 0.0 1.0 1 0 0 1 1 1 0 gp58-like protein ribosomal_L24 PF17136.4 EHT99509.1 - 5.1e-24 84.5 0.1 5.1e-24 84.5 0.1 1.6 2 0 0 2 2 2 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 EHT99509.1 - 4.2e-05 23.3 2.7 9.8e-05 22.2 2.7 1.7 1 0 0 1 1 1 1 KOW motif Ribosomal_L5_C PF00673.21 EHT99510.1 - 6.4e-41 138.4 0.0 9.8e-41 137.9 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EHT99510.1 - 6.1e-29 100.1 0.3 1.1e-28 99.3 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 DUF2862 PF11061.8 EHT99510.1 - 0.042 13.7 0.1 0.24 11.2 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2862) Ribosomal_S14 PF00253.21 EHT99511.1 - 5e-27 93.4 1.8 7e-27 93.0 1.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Ribosomal_S8 PF00410.19 EHT99512.1 - 2.4e-48 163.3 0.2 2.7e-48 163.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_L6 PF00347.23 EHT99513.1 - 6.8e-41 138.8 0.6 1.7e-19 70.3 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_L18p PF00861.22 EHT99514.1 - 1.3e-43 148.1 4.2 1.4e-43 147.9 4.2 1.0 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Ribosomal_L5e PF17144.4 EHT99514.1 - 0.011 15.8 0.1 0.012 15.6 0.1 1.1 1 0 0 1 1 1 0 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_S5_C PF03719.15 EHT99515.1 - 1.3e-30 104.7 0.7 2.3e-30 103.8 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 EHT99515.1 - 9.3e-30 102.4 3.1 9.3e-30 102.4 3.1 1.9 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_L30 PF00327.20 EHT99516.1 - 9.3e-20 70.3 0.1 1e-19 70.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L27A PF00828.19 EHT99517.1 - 1.1e-31 110.1 1.6 1.5e-31 109.8 1.6 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L18 PF17135.4 EHT99517.1 - 0.033 13.6 0.8 0.055 12.9 0.4 1.4 1 1 0 1 1 1 0 Ribosomal protein 60S L18 and 50S L18e SecY PF00344.20 EHT99518.1 - 8.5e-119 396.3 19.5 1.1e-118 396.0 19.5 1.1 1 0 0 1 1 1 1 SecY translocase Orf78 PF06024.12 EHT99518.1 - 0.091 13.1 0.3 0.36 11.2 0.3 2.0 1 0 0 1 1 1 0 Orf78 (ac78) Ribosomal_L36 PF00444.18 EHT99519.1 - 6.6e-21 74.2 8.7 7.1e-21 74.1 8.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L36 Ribosomal_S13 PF00416.22 EHT99520.1 - 3e-35 121.4 6.6 1.5e-33 115.9 6.6 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 EHT99520.1 - 0.00021 20.2 0.0 0.00022 20.1 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF5053 PF16476.5 EHT99520.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5053) Ribosomal_S11 PF00411.19 EHT99521.1 - 1.7e-54 182.9 0.8 2e-54 182.7 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Ribosomal_S4 PF00163.19 EHT99522.1 - 8.9e-32 109.9 2.7 1.4e-31 109.2 1.9 1.7 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 EHT99522.1 - 2e-19 69.0 0.4 4e-19 68.1 0.4 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 EHT99522.1 - 0.0027 17.5 0.1 0.0048 16.7 0.1 1.4 1 0 0 1 1 1 1 S4 domain DUF4158 PF13700.6 EHT99522.1 - 0.029 14.2 0.0 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4158) RNA_pol_L PF01193.24 EHT99523.1 - 3.2e-24 84.1 0.0 5.3e-24 83.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_A_CTD PF03118.15 EHT99523.1 - 4.5e-24 84.0 0.1 8e-24 83.2 0.1 1.4 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain RNA_pol_A_bac PF01000.26 EHT99523.1 - 4.8e-24 84.9 0.1 1.1e-23 83.7 0.1 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L_2 PF13656.6 EHT99523.1 - 0.00015 21.5 0.0 0.8 9.5 0.0 2.7 2 0 0 2 2 2 2 RNA polymerase Rpb3/Rpb11 dimerisation domain Ribosomal_L17 PF01196.19 EHT99524.1 - 2.5e-34 118.0 0.0 3.1e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L17 DUF1992 PF09350.10 EHT99525.1 - 4.6e-23 81.2 0.3 8.6e-23 80.3 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) ArfA PF03889.13 EHT99526.1 - 3.2e-25 87.4 1.8 4.7e-25 86.8 1.8 1.3 1 0 0 1 1 1 1 Alternative ribosome-rescue factor A MORN PF02493.20 EHT99526.1 - 0.0095 15.8 1.2 1.2 9.2 0.3 2.4 2 0 0 2 2 2 2 MORN repeat MscL PF01741.18 EHT99527.1 - 3.8e-46 156.3 1.3 4.3e-46 156.1 1.3 1.0 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL UPF0239 PF06783.11 EHT99527.1 - 0.02 15.1 0.3 0.035 14.3 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) DUF3487 PF11990.8 EHT99527.1 - 4.4 7.2 6.6 2 8.3 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3487) TrkA_N PF02254.18 EHT99528.1 - 2.9e-59 198.4 2.7 8.8e-30 103.3 0.1 2.4 2 0 0 2 2 2 2 TrkA-N domain TrkA_C PF02080.21 EHT99528.1 - 4.2e-24 84.1 4.0 4.7e-11 42.3 0.0 3.8 4 0 0 4 4 4 2 TrkA-C domain NAD_binding_7 PF13241.6 EHT99528.1 - 5.3e-12 46.1 1.6 0.00053 20.4 0.0 3.3 2 1 1 3 3 3 2 Putative NAD(P)-binding F420_oxidored PF03807.17 EHT99528.1 - 9.7e-12 45.3 1.8 7.5e-05 23.2 0.1 3.7 3 2 1 4 4 3 2 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EHT99528.1 - 5.7e-11 42.6 1.6 1.6e-05 25.0 0.2 2.6 2 1 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EHT99528.1 - 7e-10 39.3 0.8 0.00097 19.4 0.1 2.5 2 0 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 EHT99528.1 - 2.8e-07 30.8 1.2 0.013 15.7 0.0 2.5 2 0 0 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 EHT99528.1 - 4.8e-07 29.5 0.2 0.0066 16.1 0.0 3.1 3 1 0 3 3 3 2 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.6 EHT99528.1 - 1.2e-06 28.5 2.8 0.0037 17.2 0.1 2.5 2 1 0 2 2 2 2 NAD(P)H-binding AlaDh_PNT_C PF01262.21 EHT99528.1 - 1.2e-06 27.9 4.2 0.00091 18.6 0.2 2.9 2 1 1 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EHT99528.1 - 3e-06 27.3 1.8 0.026 14.4 0.1 2.5 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 EHT99528.1 - 1.2e-05 25.7 1.7 0.2 12.3 0.1 3.2 4 0 0 4 4 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EHT99528.1 - 1.7e-05 24.2 0.1 0.0058 15.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 EHT99528.1 - 2.4e-05 24.4 0.4 0.049 13.6 0.0 3.2 2 2 1 3 3 3 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GFO_IDH_MocA PF01408.22 EHT99528.1 - 0.00013 22.7 0.3 0.19 12.6 0.1 2.5 2 0 0 2 2 2 2 Oxidoreductase family, NAD-binding Rossmann fold UDPG_MGDP_dh_N PF03721.14 EHT99528.1 - 0.00051 19.7 0.0 0.0017 18.0 0.0 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF1188 PF06690.11 EHT99528.1 - 0.0017 18.0 0.1 1.9 8.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1188) ThiF PF00899.21 EHT99528.1 - 0.0045 16.4 0.5 0.22 10.8 0.1 2.5 2 0 0 2 2 2 1 ThiF family Epimerase PF01370.21 EHT99528.1 - 0.0054 16.2 0.5 0.85 9.0 0.1 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EHT99528.1 - 0.0054 16.2 0.2 0.64 9.4 0.0 2.7 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_8 PF13450.6 EHT99528.1 - 0.054 13.7 0.1 21 5.4 0.0 2.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain XdhC_C PF13478.6 EHT99528.1 - 0.056 14.0 0.7 1.2 9.7 0.1 2.4 2 1 0 2 2 2 0 XdhC Rossmann domain OAM_dimer PF16554.5 EHT99528.1 - 0.11 13.0 0.1 0.27 11.7 0.1 1.6 1 0 0 1 1 1 0 Dimerisation domain of d-ornithine 4,5-aminomutase Lycopene_cycl PF05834.12 EHT99528.1 - 0.18 10.8 0.7 5.5 5.9 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Methyltr_RsmB-F PF01189.17 EHT99529.1 - 2.3e-74 249.4 0.0 3.7e-74 248.7 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F NusB PF01029.18 EHT99529.1 - 1.2e-22 80.6 0.0 3.3e-22 79.2 0.0 1.8 1 0 0 1 1 1 1 NusB family Methyltransf_31 PF13847.6 EHT99529.1 - 1.3e-08 34.7 0.0 3.5e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 EHT99529.1 - 8.7e-06 25.9 0.0 1.5e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 EHT99529.1 - 1.5e-05 25.6 0.0 3.6e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EHT99529.1 - 0.00011 21.8 0.0 0.00025 20.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_5 PF01795.19 EHT99529.1 - 0.00032 20.3 0.0 0.00058 19.5 0.0 1.3 1 0 0 1 1 1 1 MraW methylase family DUF2431 PF10354.9 EHT99529.1 - 0.007 16.7 0.0 0.024 14.9 0.0 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF2431) Cons_hypoth95 PF03602.15 EHT99529.1 - 0.0093 15.6 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltr_RsmF_N PF17125.5 EHT99529.1 - 0.091 13.3 0.0 0.23 12.0 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of 16S rRNA methyltransferase RsmF Met_10 PF02475.16 EHT99529.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Formyl_trans_N PF00551.19 EHT99530.1 - 1.3e-53 181.4 0.0 2.2e-53 180.7 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 EHT99530.1 - 3.3e-31 107.5 0.0 5.6e-31 106.7 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Pep_deformylase PF01327.21 EHT99531.1 - 2e-49 167.3 0.0 2.3e-49 167.1 0.0 1.0 1 0 0 1 1 1 1 Polypeptide deformylase DDE_Tnp_IS66 PF03050.14 EHT99532.1 - 1.2e-97 326.8 2.7 1.2e-96 323.5 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT99532.1 - 3.3e-16 59.2 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT99532.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT99532.1 - 8.9e-12 45.6 8.5 1.9e-11 44.6 8.5 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FUSC PF04632.12 EHT99532.1 - 0.046 12.3 7.1 0.072 11.6 7.1 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Phage_HK97_TLTM PF06120.11 EHT99532.1 - 0.046 12.9 1.3 0.09 12.0 1.3 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Exonuc_VII_L PF02601.15 EHT99532.1 - 0.05 13.2 1.7 0.072 12.6 0.5 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit LXG PF04740.12 EHT99532.1 - 0.1 12.3 1.6 0.81 9.4 0.3 2.2 1 1 1 2 2 2 0 LXG domain of WXG superfamily Csm1_N PF18504.1 EHT99532.1 - 0.13 12.6 3.2 0.93 9.9 0.2 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain FAM184 PF15665.5 EHT99532.1 - 0.15 11.8 4.7 0.24 11.2 4.7 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B DHR10 PF18595.1 EHT99532.1 - 0.18 11.9 10.2 0.31 11.1 10.2 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain HalX PF08663.10 EHT99532.1 - 0.22 11.8 2.3 0.6 10.5 2.3 1.7 1 0 0 1 1 1 0 HalX domain ALIX_LYPXL_bnd PF13949.6 EHT99532.1 - 0.23 10.7 4.0 0.39 9.9 4.0 1.3 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV TSNAXIP1_N PF15739.5 EHT99532.1 - 0.26 11.7 2.9 0.56 10.6 2.9 1.5 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus ERM PF00769.19 EHT99532.1 - 0.29 10.9 10.4 0.48 10.2 10.4 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HHH_8 PF14716.6 EHT99532.1 - 0.36 11.2 4.1 0.92 9.9 2.6 2.4 2 1 0 2 2 2 0 Helix-hairpin-helix domain Zn-ribbon_8 PF09723.10 EHT99532.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain CREPT PF16566.5 EHT99532.1 - 0.48 10.6 7.6 0.22 11.7 4.5 1.8 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour HAUS-augmin3 PF14932.6 EHT99532.1 - 1.2 8.6 6.9 2.9 7.4 6.9 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 ABC_tran_CTD PF16326.5 EHT99532.1 - 2 8.7 6.7 0.3 11.4 1.2 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain SlyX PF04102.12 EHT99532.1 - 7.6 7.2 8.3 15 6.3 1.9 3.0 1 1 1 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHT99533.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHT99534.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT99534.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT99534.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT99534.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix Response_reg PF00072.24 EHT99535.1 - 1.1e-28 99.7 0.2 1.8e-28 98.9 0.2 1.4 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 EHT99535.1 - 6.5e-22 76.8 0.6 1e-21 76.2 0.6 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4 PF04545.16 EHT99535.1 - 1.4e-06 27.7 1.2 4e-06 26.2 1.2 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 EHT99535.1 - 2e-05 24.2 0.2 3.7e-05 23.3 0.2 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_10 PF04967.12 EHT99535.1 - 0.00022 21.0 0.7 0.002 17.9 0.7 2.2 1 1 0 1 1 1 1 HTH DNA binding domain HTH_23 PF13384.6 EHT99535.1 - 0.0074 16.1 0.1 0.017 14.9 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_24 PF13412.6 EHT99535.1 - 0.034 13.7 0.2 0.065 12.8 0.2 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_Tnp_ISL3 PF13542.6 EHT99535.1 - 0.059 12.8 0.1 0.17 11.3 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_20 PF12840.7 EHT99535.1 - 0.064 13.3 0.1 0.064 13.3 0.1 2.6 3 1 0 3 3 3 0 Helix-turn-helix domain HTH_12 PF08461.10 EHT99535.1 - 0.095 12.7 0.5 1.7 8.6 0.1 2.6 2 1 1 3 3 3 0 Ribonuclease R winged-helix domain DDE_3 PF13358.6 EHT99536.1 - 1.1e-22 80.3 0.0 1.9e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 EHT99536.1 - 1.1e-10 41.0 1.0 3.6e-09 36.2 0.1 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 EHT99536.1 - 4.1e-09 36.9 1.1 2.8e-08 34.3 0.3 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 EHT99536.1 - 4e-07 30.0 1.2 1.1e-06 28.6 0.3 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHT99536.1 - 1.4e-05 25.1 0.3 0.0002 21.4 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_33 PF13592.6 EHT99536.1 - 6e-05 22.6 5.4 8.3e-05 22.1 0.5 3.0 3 0 0 3 3 3 1 Winged helix-turn helix LZ_Tnp_IS481 PF13011.6 EHT99536.1 - 0.029 14.9 0.2 0.061 13.8 0.2 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 HTH_38 PF13936.6 EHT99536.1 - 0.052 13.3 0.6 0.16 11.8 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.7 EHT99537.1 - 0.078 13.2 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2158 PF09926.9 EHT99538.1 - 0.0083 15.9 0.0 0.0097 15.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized small protein (DUF2158) DUF3750 PF12570.8 EHT99539.1 - 7.4e-52 175.4 1.2 9.5e-52 175.0 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3750) Abhydrolase_3 PF07859.13 EHT99541.1 - 4.2e-69 232.6 0.1 5.9e-69 232.1 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 EHT99541.1 - 9.7e-06 24.7 0.1 1.6e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 EHT99541.1 - 3.6e-05 23.3 0.1 8.8e-05 22.1 0.1 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 EHT99541.1 - 7e-05 21.9 1.1 0.00049 19.1 1.1 2.0 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 EHT99541.1 - 0.00026 20.0 0.0 0.00036 19.5 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Chlorophyllase PF07224.11 EHT99541.1 - 0.0036 16.3 0.6 0.012 14.6 0.6 1.7 1 1 0 1 1 1 1 Chlorophyllase Abhydrolase_6 PF12697.7 EHT99541.1 - 0.019 15.6 0.3 0.029 15.0 0.3 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family AXE1 PF05448.12 EHT99541.1 - 0.091 11.4 0.1 1.4 7.5 0.1 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 EHT99541.1 - 0.11 11.8 0.0 0.97 8.6 0.0 2.1 1 1 1 2 2 2 0 Serine aminopeptidase, S33 GMP_synt_C PF00958.22 EHT99542.1 - 5.4e-44 148.2 0.0 1e-43 147.3 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 EHT99542.1 - 7.2e-40 136.8 0.0 1e-39 136.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 EHT99542.1 - 6e-09 35.4 0.1 1e-06 28.1 0.1 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 EHT99542.1 - 1.4e-08 34.7 0.0 3.3e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 EHT99542.1 - 2.1e-05 23.5 0.1 0.00011 21.1 0.1 2.0 2 0 0 2 2 2 1 tRNA methyl transferase Asn_synthase PF00733.21 EHT99542.1 - 0.0015 18.3 0.0 0.009 15.7 0.0 1.9 2 0 0 2 2 2 1 Asparagine synthase QueC PF06508.13 EHT99542.1 - 0.0093 15.5 0.0 2.7 7.4 0.0 2.5 3 0 0 3 3 3 2 Queuosine biosynthesis protein QueC ThiI PF02568.14 EHT99542.1 - 0.015 14.9 0.1 0.027 14.0 0.1 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.19 EHT99542.1 - 0.076 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.20 EHT99542.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 PP-loop family IMPDH PF00478.25 EHT99543.1 - 2.2e-159 530.1 9.5 2.5e-159 529.9 9.5 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 EHT99543.1 - 3e-15 56.4 1.9 7.2e-07 29.6 0.0 3.4 3 0 0 3 3 3 2 CBS domain NMO PF03060.15 EHT99543.1 - 4.8e-10 39.3 14.6 6.1e-05 22.6 8.0 2.7 1 1 2 3 3 3 2 Nitronate monooxygenase FMN_dh PF01070.18 EHT99543.1 - 3.6e-09 36.1 7.6 7.8e-08 31.7 6.2 2.4 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 EHT99543.1 - 0.00018 21.1 2.3 0.0082 15.6 0.3 2.3 2 0 0 2 2 2 2 Histidine biosynthesis protein DHO_dh PF01180.21 EHT99543.1 - 0.0055 16.0 9.1 0.0075 15.5 2.5 2.3 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase NanE PF04131.14 EHT99543.1 - 0.018 14.2 4.8 0.11 11.7 4.8 2.4 1 1 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase TMP-TENI PF02581.17 EHT99543.1 - 0.03 13.7 6.8 0.086 12.2 2.6 2.4 2 0 0 2 2 2 0 Thiamine monophosphate synthase Glu_synthase PF01645.17 EHT99543.1 - 0.062 12.4 9.3 0.022 13.9 6.0 1.8 2 0 0 2 2 2 0 Conserved region in glutamate synthase ThiG PF05690.14 EHT99543.1 - 0.065 12.5 7.5 0.026 13.8 3.2 2.5 3 0 0 3 3 3 0 Thiazole biosynthesis protein ThiG Exonuc_VII_L PF02601.15 EHT99544.1 - 7.7e-104 347.5 4.4 9.8e-104 347.2 4.4 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit tRNA_anti_2 PF13742.6 EHT99544.1 - 1.2e-31 108.7 0.0 7.3e-31 106.2 0.0 2.1 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA_anti-codon PF01336.25 EHT99544.1 - 9e-06 25.6 0.0 1.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain bMG10 PF17973.1 EHT99544.1 - 0.045 14.0 0.0 0.61 10.3 0.0 2.5 2 0 0 2 2 2 0 Bacterial Alpha-2-macroglobulin MG10 domain DUF5348 PF17295.2 EHT99544.1 - 0.096 12.6 0.0 28 4.7 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5348) PQQ PF01011.21 EHT99546.1 - 1.5e-41 138.4 2.4 5.8e-08 32.3 0.2 8.4 8 0 0 8 8 8 7 PQQ enzyme repeat PQQ_2 PF13360.6 EHT99546.1 - 1.2e-18 67.6 0.4 1.1e-05 25.2 0.0 4.6 4 1 0 4 4 4 4 PQQ-like domain PQQ_3 PF13570.6 EHT99546.1 - 0.023 15.2 0.3 0.12 12.9 0.1 8.5 12 1 0 12 12 12 0 PQQ-like domain ACP_syn_III_C PF08541.10 EHT99546.1 - 0.1 12.8 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF3273 PF11677.8 EHT99546.1 - 5.1 6.3 6.8 9.5 5.4 6.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3273) 7TMR-DISM_7TM PF07695.11 EHT99546.1 - 5.6 6.8 18.0 5.3 6.9 17.0 1.5 1 1 0 1 1 1 0 7TM diverse intracellular signalling MMR_HSR1 PF01926.23 EHT99547.1 - 2e-55 185.7 0.4 2.1e-28 98.7 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EHT99547.1 - 3.4e-31 107.9 0.0 1.8e-16 60.0 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B KH_dom-like PF14714.6 EHT99547.1 - 3.2e-26 91.5 0.1 7.3e-26 90.3 0.1 1.7 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal GTP_EFTU PF00009.27 EHT99547.1 - 1e-19 70.8 1.4 1.3e-09 37.9 0.1 4.9 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EHT99547.1 - 2.2e-12 47.4 0.0 0.03 14.4 0.0 4.4 3 1 1 4 4 4 3 Dynamin family AIG1 PF04548.16 EHT99547.1 - 8.1e-11 41.7 0.0 8.6e-05 22.0 0.0 2.2 2 0 0 2 2 2 2 AIG1 family RsgA_GTPase PF03193.16 EHT99547.1 - 2e-08 34.3 0.0 0.039 13.8 0.0 4.4 2 2 2 4 4 4 2 RsgA GTPase Ras PF00071.22 EHT99547.1 - 2.2e-06 27.4 0.0 0.015 14.9 0.0 3.0 2 2 0 2 2 2 2 Ras family Roc PF08477.13 EHT99547.1 - 2.8e-06 27.5 0.1 0.27 11.5 0.0 3.9 3 2 0 3 3 2 2 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 EHT99547.1 - 5.2e-06 26.2 4.5 0.17 11.5 0.1 4.0 2 2 1 4 4 4 2 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 EHT99547.1 - 8.6e-05 23.1 0.0 0.79 10.2 0.0 2.9 3 0 0 3 3 3 2 ABC transporter AAA_24 PF13479.6 EHT99547.1 - 9.6e-05 22.2 0.0 0.31 10.7 0.0 3.1 2 2 1 3 3 3 2 AAA domain TniB PF05621.11 EHT99547.1 - 0.00017 21.1 0.0 0.14 11.6 0.0 2.4 2 0 0 2 2 2 2 Bacterial TniB protein AAA_22 PF13401.6 EHT99547.1 - 0.00017 21.9 0.1 1.3 9.3 0.0 3.4 3 2 0 3 3 2 2 AAA domain SRPRB PF09439.10 EHT99547.1 - 0.00048 19.6 0.0 0.078 12.4 0.0 2.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit SRP54 PF00448.22 EHT99547.1 - 0.0016 18.1 0.2 0.67 9.6 0.0 2.8 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain NB-ARC PF00931.22 EHT99547.1 - 0.0023 17.1 0.0 1.2 8.2 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain RNA_helicase PF00910.22 EHT99547.1 - 0.0024 18.2 0.0 3.9 7.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase PduV-EutP PF10662.9 EHT99547.1 - 0.003 17.3 0.2 7.1 6.4 0.0 3.7 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 EHT99547.1 - 0.0034 17.2 0.0 0.35 10.6 0.0 3.2 2 1 0 3 3 3 1 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 EHT99547.1 - 0.0038 17.2 0.1 5.2 7.0 0.0 2.9 3 0 0 3 3 2 1 NTPase MeaB PF03308.16 EHT99547.1 - 0.0046 16.0 0.1 6.6 5.6 0.0 3.5 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Nuc_deoxyri_tr2 PF15891.5 EHT99547.1 - 0.0056 17.0 0.5 1.8 8.9 0.0 3.0 2 1 1 3 3 3 1 Nucleoside 2-deoxyribosyltransferase like AAA_18 PF13238.6 EHT99547.1 - 0.017 15.7 0.0 5.4 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EHT99547.1 - 0.019 15.1 0.0 3.4 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EHT99547.1 - 0.039 13.5 2.5 16 5.0 0.2 3.8 3 1 0 3 3 3 0 AAA domain Ploopntkinase3 PF18751.1 EHT99547.1 - 0.046 13.6 0.0 1.9 8.4 0.0 2.8 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 AAA_29 PF13555.6 EHT99547.1 - 0.048 13.4 0.0 14 5.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain KTI12 PF08433.10 EHT99547.1 - 0.061 12.8 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_16 PF13191.6 EHT99547.1 - 0.076 13.4 0.0 17 5.7 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain Septin PF00735.18 EHT99547.1 - 0.089 12.1 0.0 9.6 5.4 0.0 2.4 2 0 0 2 2 2 0 Septin NOG1 PF06858.14 EHT99547.1 - 0.097 12.5 1.6 0.38 10.6 0.1 2.5 2 1 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) AAA_28 PF13521.6 EHT99547.1 - 0.11 12.7 0.0 17 5.6 0.0 2.9 2 1 1 3 3 3 0 AAA domain AAA_14 PF13173.6 EHT99547.1 - 0.13 12.3 0.0 18 5.4 0.0 2.6 2 1 0 2 2 2 0 AAA domain PQQ_2 PF13360.6 EHT99548.1 - 7.2e-67 225.4 15.7 3.4e-53 180.7 5.9 2.8 1 1 2 3 3 3 3 PQQ-like domain PQQ PF01011.21 EHT99548.1 - 1.9e-37 125.4 10.6 1.2e-07 31.3 0.0 8.6 9 0 0 9 9 9 6 PQQ enzyme repeat PQQ_3 PF13570.6 EHT99548.1 - 2.2e-37 126.6 18.1 9.1e-06 26.0 0.0 8.6 8 0 0 8 8 8 8 PQQ-like domain WD40_like PF17005.5 EHT99548.1 - 0.0037 16.6 0.0 0.056 12.8 0.0 2.2 1 1 0 1 1 1 1 WD40-like domain RAMA PF18755.1 EHT99548.1 - 0.013 15.9 0.1 0.28 11.6 0.1 2.5 2 0 0 2 2 2 0 Restriction Enzyme Adenine Methylase Associated Glyco_hydro_98C PF08307.11 EHT99548.1 - 0.19 11.2 0.0 0.7 9.3 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 98 C-terminal domain TPR_21 PF09976.9 EHT99549.1 - 1.3e-54 184.9 10.6 1.4e-54 184.7 10.6 1.0 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain TPR_19 PF14559.6 EHT99549.1 - 1e-06 29.1 12.6 0.0063 17.0 2.7 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EHT99549.1 - 0.00015 21.3 3.3 0.00026 20.5 3.1 1.6 1 1 0 1 1 1 1 MalT-like TPR region TPR_16 PF13432.6 EHT99549.1 - 0.00017 22.2 2.9 0.0076 16.9 1.1 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EHT99549.1 - 0.00018 22.1 4.4 0.014 16.2 0.3 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EHT99549.1 - 0.0007 19.5 1.3 2.2 8.6 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat T6SS_VasJ PF16989.5 EHT99549.1 - 0.02 14.4 1.7 0.031 13.7 1.7 1.3 1 0 0 1 1 1 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ PEP-utilisers_N PF05524.13 EHT99549.1 - 0.089 13.0 0.6 0.19 11.9 0.6 1.7 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal TPR_6 PF13174.6 EHT99549.1 - 0.14 12.8 4.5 2.5 8.9 0.3 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 EHT99549.1 - 0.18 12.5 5.1 14 6.6 0.6 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat YfdX PF10938.8 EHT99549.1 - 0.7 9.8 7.5 11 5.9 0.4 3.2 2 2 1 3 3 3 0 YfdX protein TPR_17 PF13431.6 EHT99549.1 - 2 9.0 5.3 88 3.8 0.4 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat tRNA-synt_His PF13393.6 EHT99550.1 - 2.7e-45 155.0 0.0 3.5e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 EHT99550.1 - 1.4e-35 122.9 0.0 2.3e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EHT99550.1 - 2.6e-12 46.7 0.0 5.4e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2d PF01409.20 EHT99550.1 - 0.0041 16.6 0.0 0.11 11.9 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.20 EHT99550.1 - 0.0043 16.2 0.4 6.4 5.8 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class II (D, K and N) GcpE PF04551.14 EHT99551.1 - 2.4e-130 434.7 0.2 2.8e-130 434.5 0.2 1.0 1 0 0 1 1 1 1 GcpE protein DUF4115 PF13464.6 EHT99552.1 - 2.2e-23 82.2 0.0 4.9e-23 81.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4115) HTH_25 PF13413.6 EHT99552.1 - 2.9e-14 52.7 0.4 5.2e-14 51.9 0.4 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 EHT99552.1 - 6.4e-08 32.8 0.2 1.7e-07 31.4 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 EHT99552.1 - 4.2e-06 26.7 0.0 9.5e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 EHT99552.1 - 1.6e-05 24.9 0.0 2.9e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain SOG2 PF10428.9 EHT99552.1 - 0.042 13.0 7.2 0.051 12.8 7.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Sigma70_r4 PF04545.16 EHT99552.1 - 0.17 11.4 0.1 0.3 10.6 0.1 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 TPR_2 PF07719.17 EHT99553.1 - 9.8e-08 31.6 17.2 0.076 13.2 0.9 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 EHT99553.1 - 2.8e-07 30.7 21.6 2.5e-05 24.5 3.6 3.7 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EHT99553.1 - 1.4e-06 28.7 19.6 0.0014 19.1 1.3 4.0 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 EHT99553.1 - 0.00028 21.0 13.8 0.00049 20.3 0.4 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_21 PF09976.9 EHT99553.1 - 0.00049 19.9 11.3 0.00062 19.5 5.4 2.4 2 1 1 3 3 3 1 Tetratricopeptide repeat-like domain TPR_16 PF13432.6 EHT99553.1 - 0.0011 19.6 28.0 0.039 14.6 5.4 3.4 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EHT99553.1 - 0.0028 18.3 26.4 0.075 13.9 2.9 5.6 2 1 4 6 6 6 3 Tetratricopeptide repeat DUF410 PF04190.13 EHT99553.1 - 0.0041 17.0 1.9 0.031 14.1 0.3 2.6 1 1 2 3 3 3 1 Protein of unknown function (DUF410) TPR_8 PF13181.6 EHT99553.1 - 0.0054 16.8 6.9 6.5 7.2 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat HemY_N PF07219.13 EHT99553.1 - 0.0063 16.7 9.2 0.048 13.9 1.2 2.6 2 1 1 3 3 3 2 HemY protein N-terminus DUF2491 PF10679.9 EHT99553.1 - 0.0069 15.6 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2491) TPR_10 PF13374.6 EHT99553.1 - 0.057 13.3 0.2 0.057 13.3 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EHT99553.1 - 0.37 10.7 15.0 1.6 8.7 0.4 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 EHT99553.1 - 1.8 8.7 15.1 1.5 9.0 4.5 3.6 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 EHT99553.1 - 2.1 8.7 8.6 7 7.1 1.2 3.3 1 1 3 4 4 4 0 Tetratricopeptide repeat Radical_SAM PF04055.21 EHT99554.1 - 2.8e-17 63.6 0.1 1.6e-16 61.1 0.0 2.3 2 1 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.6 EHT99554.1 - 0.0011 19.1 0.0 0.0029 17.7 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 EHT99554.1 - 0.054 13.8 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 4Fe-4S single cluster domain NDK PF00334.19 EHT99555.1 - 1.6e-56 190.0 0.0 1.8e-56 189.9 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Transgly PF00912.22 EHT99556.1 - 1.2e-47 161.7 0.0 1.7e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase Transpeptidase PF00905.22 EHT99556.1 - 4e-14 52.5 0.0 2.9e-13 49.7 0.0 1.9 1 1 0 1 1 1 1 Penicillin binding protein transpeptidase domain BiPBP_C PF06832.12 EHT99556.1 - 7.9e-13 48.3 0.2 7.9e-13 48.3 0.2 2.6 4 0 0 4 4 4 1 Penicillin-Binding Protein C-terminus Family bMG10 PF17973.1 EHT99557.1 - 5.6e-28 97.7 0.0 1.4e-27 96.4 0.0 1.7 1 0 0 1 1 1 1 Bacterial Alpha-2-macroglobulin MG10 domain A2M_BRD PF07703.14 EHT99557.1 - 3.7e-10 40.3 0.0 1.7e-09 38.2 0.0 2.1 2 0 0 2 2 2 1 Alpha-2-macroglobulin bait region domain TED_complement PF07678.14 EHT99557.1 - 4.8e-09 35.7 0.0 8.1e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 A-macroglobulin TED domain A2M PF00207.22 EHT99557.1 - 3.9e-06 26.6 0.0 1.7e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Alpha-2-macroglobulin family DUF2744 PF10910.8 EHT99557.1 - 0.0044 17.0 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2744) FixG_C PF11614.8 EHT99557.1 - 0.074 13.3 0.0 0.5 10.6 0.0 2.3 2 0 0 2 2 2 0 IG-like fold at C-terminal of FixG, putative oxidoreductase Myco_19_kDa PF05481.12 EHT99557.1 - 0.17 12.2 0.0 0.5 10.7 0.0 1.7 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen bMG5 PF17972.1 EHT99558.1 - 4.5e-42 143.4 0.1 9.2e-42 142.4 0.0 1.5 2 0 0 2 2 2 1 Bacterial Alpha-2-macroglobulin MG5 domain bMG6 PF17962.1 EHT99558.1 - 7.2e-30 103.4 0.4 2.6e-29 101.7 0.1 1.9 2 0 0 2 2 2 1 Bacterial macroglobulin domain 6 MG3 PF17791.1 EHT99558.1 - 0.0043 17.3 0.0 0.011 15.9 0.0 1.7 2 0 0 2 2 2 1 Macroglobulin domain MG3 bMG1 PF17970.1 EHT99559.1 - 5.5e-41 138.9 0.0 1e-40 138.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial Alpha-2-macroglobulin MG1 domain MG2 PF01835.19 EHT99559.1 - 1.5e-19 70.2 0.0 1e-18 67.6 0.0 2.4 2 0 0 2 2 2 1 MG2 domain bMG3 PF11974.8 EHT99559.1 - 7.1e-19 67.7 0.0 1.9e-18 66.4 0.0 1.8 1 0 0 1 1 1 1 Bacterial alpha-2-macroglobulin MG3 domain Big_1 PF02369.16 EHT99559.1 - 1.2e-05 25.2 0.5 0.074 13.1 0.0 2.5 2 0 0 2 2 2 2 Bacterial Ig-like domain (group 1) CarboxypepD_reg PF13620.6 EHT99559.1 - 0.00023 21.3 0.0 0.0031 17.7 0.0 2.5 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain MG4 PF17789.1 EHT99559.1 - 0.0035 17.4 0.1 0.64 10.2 0.0 2.7 2 0 0 2 2 2 1 Macroglobulin domain MG4 Big_10 PF17964.1 EHT99559.1 - 0.0085 16.1 0.0 0.054 13.5 0.0 2.1 2 0 0 2 2 2 1 Bacterial Ig domain Invasin_D3 PF09134.10 EHT99559.1 - 0.017 15.4 0.0 1.3 9.4 0.0 2.9 2 0 0 2 2 2 0 Invasin, domain 3 Big_5 PF13205.6 EHT99559.1 - 0.058 14.1 0.0 0.12 13.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain SdrD_B PF17210.3 EHT99559.1 - 0.12 12.7 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 SdrD B-like domain Ephrin_lbd PF01404.19 EHT99559.1 - 0.26 11.3 0.0 0.43 10.6 0.0 1.2 1 0 0 1 1 1 0 Ephrin receptor ligand binding domain Rhodanese PF00581.20 EHT99560.1 - 1.4e-29 102.7 0.0 8.4e-16 58.4 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain Peripla_BP_3 PF13377.6 EHT99560.1 - 0.086 13.2 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein-like domain SseB_C PF14581.6 EHT99561.1 - 2.5e-29 101.5 0.0 4.1e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 SseB protein C-terminal domain SseB PF07179.12 EHT99561.1 - 1.3e-22 80.3 0.2 2e-22 79.8 0.2 1.3 1 0 0 1 1 1 1 SseB protein N-terminal domain Peptidase_M17 PF00883.21 EHT99562.1 - 2.7e-102 342.2 0.0 3.3e-102 341.9 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain DUF3663 PF12404.8 EHT99562.1 - 1.6e-36 124.1 0.3 2.9e-36 123.3 0.3 1.4 1 0 0 1 1 1 1 Peptidase Aminotran_5 PF00266.19 EHT99563.1 - 1.7e-85 287.2 0.0 2e-85 287.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EHT99563.1 - 2.7e-05 23.6 0.0 3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EHT99563.1 - 0.00085 18.0 0.0 0.0013 17.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EHT99563.1 - 0.055 12.8 0.2 0.081 12.2 0.2 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Rrf2 PF02082.20 EHT99564.1 - 3.7e-27 94.5 0.2 8.5e-27 93.3 0.1 1.6 2 0 0 2 2 2 1 Transcriptional regulator HrcA_DNA-bdg PF03444.15 EHT99564.1 - 0.0087 15.7 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding MarR_2 PF12802.7 EHT99564.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_AraC PF00165.23 EHT99564.1 - 0.081 13.1 0.0 0.25 11.5 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_47 PF16221.5 EHT99564.1 - 0.15 11.6 0.0 0.72 9.5 0.0 1.9 2 0 0 2 2 2 0 winged helix-turn-helix SpoU_methylase PF00588.19 EHT99565.1 - 4.9e-34 117.5 0.0 6.5e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family Methyltrn_RNA_4 PF09936.9 EHT99565.1 - 4.5e-05 23.4 0.0 0.0082 16.0 0.0 2.2 1 1 1 2 2 2 2 SAM-dependent RNA methyltransferase DUF573 PF04504.14 EHT99565.1 - 0.039 14.6 0.0 10 6.9 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function, DUF573 DUF531 PF04407.12 EHT99565.1 - 0.067 13.3 0.0 0.14 12.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF531) Inositol_P PF00459.25 EHT99566.1 - 6.7e-74 248.8 0.0 7.5e-74 248.7 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 EHT99566.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain LMBR1 PF04791.16 EHT99567.1 - 0.00033 19.7 0.1 0.00046 19.2 0.1 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein Virul_fac_BrkB PF03631.15 EHT99567.1 - 0.012 15.3 3.9 0.012 15.3 3.9 2.7 2 1 1 3 3 3 0 Virulence factor BrkB DUF883 PF05957.13 EHT99567.1 - 0.027 15.0 6.9 0.027 15.0 6.9 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF3792 PF12670.7 EHT99567.1 - 0.029 14.5 17.8 0.083 13.1 15.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3792) DUF2225 PF09986.9 EHT99567.1 - 0.053 13.2 3.0 0.097 12.4 3.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) LPD38 PF18857.1 EHT99567.1 - 0.067 13.3 0.2 0.19 11.9 0.1 1.7 1 1 1 2 2 2 0 Large polyvalent protein associated domain 38 LAP1C PF05609.12 EHT99567.1 - 0.068 12.3 8.9 0.09 11.9 8.9 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) TerC PF03741.16 EHT99567.1 - 0.45 10.2 6.6 0.23 11.1 3.1 2.1 2 1 0 2 2 2 0 Integral membrane protein TerC family DFF40 PF09230.10 EHT99567.1 - 0.64 9.6 4.0 1.1 8.8 4.0 1.4 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa Peptidase_M4_C PF02868.15 EHT99567.1 - 0.99 9.2 8.3 1.6 8.6 8.2 1.4 1 1 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain TACC_C PF05010.14 EHT99567.1 - 1.5 8.5 20.4 42 3.8 20.4 2.1 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal LEA_4 PF02987.16 EHT99567.1 - 2 8.6 8.0 1 9.5 5.3 1.9 2 0 0 2 2 2 0 Late embryogenesis abundant protein V_ATPase_I PF01496.19 EHT99567.1 - 3.3 5.5 9.9 4.1 5.2 9.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2368 PF10166.9 EHT99567.1 - 3.3 7.3 9.1 0.35 10.5 4.0 2.0 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2368) DUF1129 PF06570.11 EHT99567.1 - 3.8 7.0 7.0 0.32 10.4 0.3 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) GET2 PF08690.10 EHT99567.1 - 4.1 7.0 10.9 6.3 6.4 10.9 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 DivIVA PF05103.13 EHT99567.1 - 4.2 7.5 26.8 0.99 9.5 10.2 2.4 1 1 1 2 2 2 0 DivIVA protein TetR_C_13 PF16925.5 EHT99567.1 - 6.6 6.7 8.1 3.4 7.6 4.1 2.1 1 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DHR10 PF18595.1 EHT99567.1 - 7.4 6.7 28.1 0.26 11.4 6.4 2.2 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Dicty_REP PF05086.12 EHT99567.1 - 8.7 4.2 9.6 11 3.8 9.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein NicO PF03824.16 EHT99568.1 - 2.5e-36 125.5 20.0 1.3e-22 80.5 5.6 2.3 1 1 1 2 2 2 2 High-affinity nickel-transport protein Rsm22 PF09243.10 EHT99568.1 - 0.011 15.0 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 DsbD_2 PF13386.6 EHT99568.1 - 0.23 11.4 25.2 2.8 7.9 17.5 2.8 1 1 1 2 2 2 0 Cytochrome C biogenesis protein transmembrane region Trp_oprn_chp PF09534.10 EHT99568.1 - 3.2 7.5 19.9 0.064 13.0 7.4 3.1 1 1 2 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF1007 PF06226.13 EHT99569.1 - 4.2e-60 203.3 0.0 4.7e-60 203.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1007) PRD PF00874.20 EHT99570.1 - 1.8e-14 53.8 0.1 3.6e-12 46.4 0.0 2.7 2 1 0 2 2 2 2 PRD domain MFS_1_like PF12832.7 EHT99571.1 - 7.8e-43 146.8 29.7 2.5e-42 145.1 29.7 1.7 1 1 0 1 1 1 1 MFS_1 like family Nuc_H_symport PF03825.16 EHT99571.1 - 2e-13 50.1 22.8 2.6e-13 49.7 22.8 1.0 1 0 0 1 1 1 1 Nucleoside H+ symporter MFS_1 PF07690.16 EHT99571.1 - 9.2e-11 41.2 40.6 9.2e-11 41.2 40.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 EHT99571.1 - 1.5e-10 40.5 24.9 8.2e-10 38.0 25.2 2.1 1 1 0 1 1 1 1 LacY proton/sugar symporter SHMT PF00464.19 EHT99572.1 - 4.6e-186 618.2 0.1 5.3e-186 618.0 0.1 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 EHT99572.1 - 9.1e-11 41.5 0.0 1.3e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EHT99572.1 - 5.8e-06 25.8 0.0 1.2e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EHT99572.1 - 6.3e-06 25.4 0.0 9.5e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 EHT99572.1 - 0.0052 15.6 0.0 0.0084 14.9 0.0 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain DegT_DnrJ_EryC1 PF01041.17 EHT99572.1 - 0.024 14.0 0.1 0.034 13.5 0.1 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EHT99572.1 - 0.13 10.7 0.0 0.3 9.6 0.0 1.6 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme NAD_binding_1 PF00175.21 EHT99573.1 - 3.9e-15 56.4 0.0 1.9e-14 54.2 0.0 2.1 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain Globin PF00042.22 EHT99573.1 - 8.1e-13 48.9 0.0 1.4e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 Globin FAD_binding_6 PF00970.24 EHT99573.1 - 1.8e-08 34.6 0.0 4.8e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.8 EHT99573.1 - 0.0012 18.7 0.1 0.0023 17.9 0.1 1.5 1 0 0 1 1 1 1 Protoglobin P-II PF00543.22 EHT99575.1 - 1.7e-43 147.4 2.8 1.9e-43 147.2 2.8 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II Sigma54_activat PF00158.26 EHT99576.1 - 4e-72 241.4 0.0 6.3e-72 240.7 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 EHT99576.1 - 3.5e-30 104.4 0.0 7.7e-30 103.4 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activ_2 PF14532.6 EHT99576.1 - 1.7e-22 80.0 0.0 1.7e-21 76.8 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.14 EHT99576.1 - 2.5e-08 34.0 0.0 5.3e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EHT99576.1 - 0.00016 22.1 0.0 0.0004 20.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 EHT99576.1 - 0.00096 19.3 0.0 0.0019 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_3 PF07726.11 EHT99576.1 - 0.002 18.0 0.0 0.024 14.5 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EHT99576.1 - 0.0061 16.0 0.1 2.4 7.5 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 EHT99576.1 - 0.0067 16.8 0.1 0.019 15.4 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain MCM PF00493.23 EHT99576.1 - 0.015 14.4 0.0 0.036 13.2 0.0 1.6 1 1 0 1 1 1 0 MCM P-loop domain HTH_8 PF02954.19 EHT99576.1 - 0.016 15.0 0.2 0.057 13.2 0.2 2.1 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family OKR_DC_1_N PF03709.15 EHT99576.1 - 0.017 15.4 0.0 0.099 12.9 0.0 2.2 3 0 0 3 3 3 0 Orn/Lys/Arg decarboxylase, N-terminal domain UPF0175 PF03683.13 EHT99576.1 - 0.028 14.1 0.0 0.089 12.5 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) IstB_IS21 PF01695.17 EHT99576.1 - 0.058 13.1 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 EHT99576.1 - 0.081 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_22 PF13401.6 EHT99576.1 - 0.086 13.1 0.0 17 5.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain Glyco_trans_1_4 PF13692.6 EHT99576.1 - 0.097 13.1 0.1 0.79 10.1 0.0 2.4 2 1 0 2 2 2 0 Glycosyl transferases group 1 AAA_7 PF12775.7 EHT99576.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region IDEAL PF08858.10 EHT99576.1 - 0.21 11.4 2.5 0.57 10.0 0.8 2.6 2 0 0 2 2 2 0 IDEAL domain Lipoprotein_20 PF13942.6 EHT99577.1 - 2.5e-56 190.3 9.8 5.1e-50 169.8 3.0 2.0 1 1 1 2 2 2 2 YfhG lipoprotein LAGLIDADG_WhiA PF14527.6 EHT99577.1 - 0.0053 16.8 0.0 0.008 16.2 0.0 1.4 1 0 0 1 1 1 1 WhiA LAGLIDADG-like domain HATPase_c PF02518.26 EHT99578.1 - 2.3e-17 63.5 0.1 7.4e-17 61.9 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EHT99578.1 - 8.2e-13 48.2 2.2 3.5e-12 46.2 2.2 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 EHT99578.1 - 0.00035 20.9 0.6 0.0013 19.0 0.0 2.4 3 0 0 3 3 3 1 HAMP domain HATPase_c_5 PF14501.6 EHT99578.1 - 0.0015 18.4 0.0 0.0027 17.6 0.0 1.4 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 EHT99578.1 - 0.15 12.0 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain GATase_5 PF13507.6 EHT99579.1 - 1.7e-104 348.6 0.0 2.9e-104 347.8 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 EHT99579.1 - 1.4e-45 155.2 2.0 1.3e-30 106.6 0.0 2.5 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 EHT99579.1 - 8.1e-45 151.5 0.0 1.6e-44 150.5 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 EHT99579.1 - 5.8e-23 81.2 0.1 2.3e-22 79.3 0.0 2.2 3 0 0 3 3 3 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 EHT99579.1 - 0.039 14.6 4.6 0.48 11.1 0.0 4.0 4 1 0 4 4 4 0 AIR synthase related protein, N-terminal domain SBP_bac_3 PF00497.20 EHT99580.1 - 2.1e-35 122.2 0.0 3.3e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 SLT PF01464.20 EHT99580.1 - 3.2e-23 81.6 0.0 6.3e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 Transglycosylase SLT domain LysR_substrate PF03466.20 EHT99580.1 - 0.0013 18.1 0.1 0.26 10.6 0.0 2.4 2 0 0 2 2 2 2 LysR substrate binding domain Lysozyme_like PF13702.6 EHT99580.1 - 0.0017 18.1 0.1 0.0034 17.1 0.1 1.6 1 0 0 1 1 1 1 Lysozyme-like MafB19-deam PF14437.6 EHT99581.1 - 3.7e-34 117.4 0.0 4.5e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 EHT99581.1 - 6.2e-28 96.6 0.0 8.8e-28 96.2 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region SNAD4 PF18750.1 EHT99581.1 - 5.5e-05 23.3 0.0 0.00021 21.4 0.0 1.8 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 Bd3614-deam PF14439.6 EHT99581.1 - 0.00022 21.3 0.0 0.00044 20.3 0.0 1.6 1 0 0 1 1 1 1 Bd3614-like deaminase APOBEC2 PF18772.1 EHT99581.1 - 0.0019 18.3 0.0 0.0042 17.2 0.0 1.5 2 0 0 2 2 2 1 APOBEC2 NAD2 PF18782.1 EHT99581.1 - 0.0035 17.5 0.0 0.0057 16.8 0.0 1.3 1 0 0 1 1 1 1 Novel AID APOBEC clade 2 APOBEC3 PF18771.1 EHT99581.1 - 0.0061 16.7 0.0 0.03 14.4 0.0 1.8 2 0 0 2 2 2 1 APOBEC3 NAD1 PF18778.1 EHT99581.1 - 0.0093 16.1 0.0 0.019 15.0 0.0 1.5 2 0 0 2 2 2 1 Novel AID APOBEC clade 1 APOBEC_N PF08210.11 EHT99581.1 - 0.011 15.7 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 APOBEC-like N-terminal domain HAD PF12710.7 EHT99582.1 - 2.5e-13 50.9 0.0 3.2e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase SIS PF01380.22 EHT99583.1 - 6.4e-27 94.0 0.8 9.7e-27 93.4 0.8 1.3 1 0 0 1 1 1 1 SIS domain HTH_6 PF01418.17 EHT99583.1 - 1.1e-26 92.6 0.1 3e-26 91.2 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family SIS_2 PF13580.6 EHT99583.1 - 1.8e-06 28.0 0.4 0.0016 18.4 0.1 2.5 1 1 1 2 2 2 2 SIS domain HupF_HypC PF01455.18 EHT99583.1 - 0.0044 17.1 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 HupF/HypC family HTH_Crp_2 PF13545.6 EHT99583.1 - 0.011 15.7 0.1 0.047 13.7 0.0 2.1 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain IF2_N PF04760.15 EHT99583.1 - 0.013 15.3 1.1 0.33 10.8 0.1 2.9 3 0 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region Peptidase_M17_N PF02789.17 EHT99583.1 - 0.029 14.2 0.3 0.055 13.3 0.3 1.6 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain Rrf2 PF02082.20 EHT99583.1 - 0.033 14.5 1.4 0.63 10.4 0.0 3.0 3 1 1 4 4 4 0 Transcriptional regulator HTH_11 PF08279.12 EHT99583.1 - 0.076 13.0 0.2 0.33 10.9 0.0 2.1 2 0 0 2 2 2 0 HTH domain MarR PF01047.22 EHT99583.1 - 0.098 12.6 0.0 0.48 10.4 0.0 2.2 2 0 0 2 2 2 0 MarR family HicA_toxin PF07927.12 EHT99584.1 - 4.3e-20 71.5 0.8 4.5e-20 71.4 0.8 1.0 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, HicB_lk_antitox PF15919.5 EHT99585.1 - 1.6e-46 157.4 0.0 1.8e-46 157.3 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system DUF2612 PF11041.8 EHT99586.1 - 3.6e-50 170.4 0.0 4e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2612) Baseplate_J PF04865.14 EHT99587.1 - 8.2e-13 48.1 3.6 3.2e-12 46.2 3.6 1.9 1 1 0 1 1 1 1 Baseplate J-like protein Big_3_2 PF12245.8 EHT99587.1 - 0.028 14.7 0.3 0.1 12.9 0.1 2.0 2 0 0 2 2 2 0 Bacterial Ig-like domain DDE_Tnp_IS66 PF03050.14 EHT99588.1 - 5.2e-86 288.6 5.3 9.1e-86 287.8 0.1 2.1 2 0 0 2 2 2 1 Transposase IS66 family zf-IS66 PF13005.7 EHT99588.1 - 1.2e-14 54.4 1.5 2.9e-14 53.2 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT99588.1 - 9.5e-12 45.5 9.0 2.1e-11 44.4 9.0 1.7 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHT99588.1 - 0.013 15.3 6.4 0.022 14.6 6.4 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Csm1_N PF18504.1 EHT99588.1 - 0.017 15.5 4.4 0.072 13.4 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Phage_HK97_TLTM PF06120.11 EHT99588.1 - 0.017 14.3 1.7 0.035 13.3 1.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein FUSC PF04632.12 EHT99588.1 - 0.029 12.9 6.8 0.048 12.2 6.8 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 EHT99588.1 - 0.031 13.9 2.4 0.037 13.6 0.8 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit Tho2 PF11262.8 EHT99588.1 - 0.042 13.0 0.4 0.071 12.3 0.4 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Troponin PF00992.20 EHT99588.1 - 0.049 13.9 3.1 0.088 13.1 3.1 1.4 1 0 0 1 1 1 0 Troponin LXG PF04740.12 EHT99588.1 - 0.082 12.6 2.7 0.28 10.9 0.4 2.2 1 1 1 2 2 2 0 LXG domain of WXG superfamily UME PF08064.13 EHT99588.1 - 0.11 12.4 0.7 18 5.3 0.0 3.1 2 1 1 3 3 3 0 UME (NUC010) domain ERM PF00769.19 EHT99588.1 - 0.12 12.1 10.8 0.21 11.4 10.8 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Zn-ribbon_8 PF09723.10 EHT99588.1 - 0.27 11.4 1.7 0.86 9.8 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain DHR10 PF18595.1 EHT99588.1 - 0.3 11.2 10.9 0.54 10.3 10.9 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF1192 PF06698.11 EHT99588.1 - 0.36 10.9 5.3 2.9 8.0 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHT99588.1 - 0.9 8.7 3.1 1.4 8.1 3.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHT99588.1 - 2.1 7.9 7.8 4.9 6.7 7.8 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 HalX PF08663.10 EHT99588.1 - 2.6 8.4 6.9 0.49 10.8 3.1 1.7 2 0 0 2 2 1 0 HalX domain OmpH PF03938.14 EHT99588.1 - 2.8 8.3 8.0 5.7 7.3 8.0 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 EHT99588.1 - 5.2 7.8 8.8 10 6.8 1.8 3.1 1 1 1 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHT99589.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHT99590.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT99590.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT99590.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT99590.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix DUF494 PF04361.13 EHT99591.1 - 6.8e-58 194.9 3.6 7.5e-58 194.7 3.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF494) zf-C4_Topoisom PF01396.19 EHT99592.1 - 4.9e-48 160.6 19.6 2.2e-15 56.2 0.6 4.2 4 0 0 4 4 4 4 Topoisomerase DNA binding C4 zinc finger zf-ribbon_3 PF13248.6 EHT99592.1 - 0.0001 21.6 12.1 1.3 8.6 0.2 5.4 5 0 0 5 5 5 2 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 EHT99592.1 - 0.00022 21.1 0.9 0.49 10.4 0.0 4.1 3 1 0 3 3 3 1 PhnA Zinc-Ribbon Zn_Tnp_IS1 PF03811.13 EHT99592.1 - 0.00026 20.7 18.3 0.083 12.6 0.3 4.5 4 0 0 4 4 4 3 InsA N-terminal domain Zn-ribbon_8 PF09723.10 EHT99592.1 - 0.00056 20.0 15.4 1.8 8.7 1.2 4.6 4 0 0 4 4 4 3 Zinc ribbon domain DUF1272 PF06906.11 EHT99592.1 - 0.011 15.8 9.1 5.1 7.3 0.1 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1272) zf-TFIIB PF13453.6 EHT99592.1 - 0.014 14.7 10.6 3.1 7.2 0.2 4.4 4 0 0 4 4 4 0 Transcription factor zinc-finger zf-ISL3 PF14690.6 EHT99592.1 - 0.018 15.7 11.4 3.7 8.3 0.2 4.5 4 0 0 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zinc_ribbon_2 PF13240.6 EHT99592.1 - 0.023 14.4 13.9 1.7 8.5 0.1 5.1 5 0 0 5 5 5 0 zinc-ribbon domain YacG PF03884.14 EHT99592.1 - 0.026 14.3 11.6 5.2 6.9 0.8 4.4 4 0 0 4 4 4 0 DNA gyrase inhibitor YacG zf-LITAF-like PF10601.9 EHT99592.1 - 0.045 14.0 11.5 0.13 12.5 3.4 3.3 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain zinc_ribbon_9 PF14369.6 EHT99592.1 - 0.057 13.7 12.5 6.4 7.1 0.4 4.8 4 0 0 4 4 4 0 zinc-ribbon Auto_anti-p27 PF06677.12 EHT99592.1 - 0.16 12.2 12.0 1 9.6 0.6 4.3 4 0 0 4 4 4 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 EHT99592.1 - 0.36 10.9 20.2 1.8e+04 -5.1 20.2 4.1 1 1 0 1 1 0 0 Double zinc ribbon RNA_POL_M_15KD PF02150.16 EHT99592.1 - 0.37 10.7 0.2 0.37 10.7 0.2 4.1 4 1 1 5 5 5 0 RNA polymerases M/15 Kd subunit DUF3797 PF12677.7 EHT99592.1 - 0.49 10.3 9.0 3.2 7.7 0.0 4.4 4 1 0 4 4 4 0 Domain of unknown function (DUF3797) DUF983 PF06170.12 EHT99592.1 - 0.55 10.7 2.8 26 5.3 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF983) TF_Zn_Ribbon PF08271.12 EHT99592.1 - 0.6 9.7 7.8 15 5.2 0.0 4.0 4 0 0 4 4 4 0 TFIIB zinc-binding zinc_ribbon_4 PF13717.6 EHT99592.1 - 0.7 9.9 11.6 30 4.7 0.3 4.9 5 0 0 5 5 4 0 zinc-ribbon domain Lar_restr_allev PF14354.6 EHT99592.1 - 1 9.8 22.8 1.3 9.5 0.6 4.1 2 1 2 4 4 4 0 Restriction alleviation protein Lar Rubredoxin PF00301.20 EHT99592.1 - 1.5 8.9 12.7 3 7.9 0.1 4.4 4 0 0 4 4 4 0 Rubredoxin Ogr_Delta PF04606.12 EHT99592.1 - 1.6 8.8 21.0 2.5 8.1 0.2 5.0 5 1 0 5 5 4 0 Ogr/Delta-like zinc finger Zn_Tnp_IS1595 PF12760.7 EHT99592.1 - 4.8 7.2 22.6 1.6 8.8 0.5 4.6 4 0 0 4 4 4 0 Transposase zinc-ribbon domain ADK_lid PF05191.14 EHT99592.1 - 4.9 7.2 16.4 7.7 6.6 0.1 4.7 5 0 0 5 5 5 0 Adenylate kinase, active site lid HypA PF01155.19 EHT99592.1 - 5.7 7.0 15.7 18 5.4 1.0 3.8 1 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-NADH-PPase PF09297.11 EHT99592.1 - 6 6.6 21.4 2.3 7.9 0.1 5.1 5 1 0 5 5 4 0 NADH pyrophosphatase zinc ribbon domain zf-RRN7 PF11781.8 EHT99592.1 - 6.5 6.5 14.7 3.5 7.4 0.1 4.0 4 0 0 4 4 4 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 PADR1 PF08063.12 EHT99592.1 - 8.1 6.3 16.8 2.9 7.8 0.6 4.5 4 1 0 4 4 4 0 PADR1 (NUC008) domain Ribosomal_L37ae PF01780.19 EHT99592.1 - 9.1 6.4 8.2 4.5 7.4 0.1 3.4 3 1 1 4 4 4 0 Ribosomal L37ae protein family DUF2752 PF10825.8 EHT99592.1 - 9.5 6.4 7.8 44 4.2 1.8 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2752) Sua5_yciO_yrdC PF01300.18 EHT99593.1 - 1.9e-43 148.0 0.0 2.1e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 Telomere recombination Shikimate_dh_N PF08501.11 EHT99594.1 - 2.7e-25 88.4 0.0 4.5e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 EHT99594.1 - 3.1e-10 39.6 0.2 3.1e-10 39.6 0.2 1.9 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 EHT99594.1 - 1.7e-09 37.9 0.1 2.6e-09 37.3 0.1 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EHT99594.1 - 0.027 14.9 0.0 0.047 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF1488 PF07369.11 EHT99595.1 - 3.8e-22 78.1 0.1 4.3e-22 77.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1488) Hexapep PF00132.24 EHT99596.1 - 3.2e-15 55.2 10.6 9.9e-08 31.4 2.3 4.2 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EHT99596.1 - 1e-07 31.5 6.8 0.00034 20.3 1.4 3.4 2 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase LZ_Tnp_IS66 PF13007.7 EHT99597.1 - 1.3e-12 48.3 9.0 2.1e-12 47.6 9.0 1.4 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHT99597.1 - 0.0013 18.6 6.2 0.0016 18.2 6.2 1.1 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B Csm1_N PF18504.1 EHT99597.1 - 0.0015 18.8 5.7 0.013 15.9 0.7 2.5 1 1 1 2 2 2 1 Csm1 N-terminal domain FUSC PF04632.12 EHT99597.1 - 0.0032 16.1 6.8 0.0033 16.0 6.8 1.0 1 0 0 1 1 1 1 Fusaric acid resistance protein family LXG PF04740.12 EHT99597.1 - 0.0038 17.0 2.8 0.041 13.6 0.4 2.0 1 1 1 2 2 2 1 LXG domain of WXG superfamily Phage_HK97_TLTM PF06120.11 EHT99597.1 - 0.0051 16.0 2.4 0.0064 15.7 2.4 1.2 1 0 0 1 1 1 1 Tail length tape measure protein Exonuc_VII_L PF02601.15 EHT99597.1 - 0.0075 15.9 1.8 0.0081 15.8 1.8 1.0 1 0 0 1 1 1 1 Exonuclease VII, large subunit ERM PF00769.19 EHT99597.1 - 0.014 15.2 10.8 0.017 14.9 10.8 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Tho2 PF11262.8 EHT99597.1 - 0.017 14.4 2.0 0.02 14.1 1.4 1.3 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 PDCD7 PF16021.5 EHT99597.1 - 0.026 13.7 3.8 0.047 12.8 3.7 1.3 1 1 0 1 1 1 0 Programmed cell death protein 7 DHR10 PF18595.1 EHT99597.1 - 0.035 14.1 10.9 0.049 13.7 10.9 1.1 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Troponin PF00992.20 EHT99597.1 - 0.039 14.3 6.1 0.067 13.5 6.1 1.3 1 1 0 1 1 1 0 Troponin RD3 PF14473.6 EHT99597.1 - 0.056 13.3 2.3 0.076 12.8 2.3 1.2 1 0 0 1 1 1 0 RD3 protein TMPIT PF07851.13 EHT99597.1 - 0.059 12.6 2.4 0.075 12.3 2.4 1.0 1 0 0 1 1 1 0 TMPIT-like protein Zn-ribbon_8 PF09723.10 EHT99597.1 - 0.081 13.1 0.2 0.19 11.8 0.2 1.7 1 0 0 1 1 1 0 Zinc ribbon domain PCRF PF03462.18 EHT99597.1 - 0.095 12.6 3.5 0.12 12.2 3.5 1.1 1 0 0 1 1 1 0 PCRF domain ATG16 PF08614.11 EHT99597.1 - 0.12 12.6 10.2 0.42 10.8 2.1 2.1 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF3145 PF11343.8 EHT99597.1 - 0.13 11.8 0.7 0.31 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3145) HAUS-augmin3 PF14932.6 EHT99597.1 - 0.15 11.6 7.9 0.4 10.2 7.9 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF948 PF06103.11 EHT99597.1 - 0.24 11.7 1.7 14 6.0 0.1 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) HalX PF08663.10 EHT99597.1 - 0.24 11.7 7.2 0.06 13.7 3.1 1.9 2 0 0 2 2 2 0 HalX domain Mt_ATP-synt_D PF05873.12 EHT99597.1 - 0.24 11.2 3.5 1.8 8.4 0.1 2.1 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Lebercilin PF15619.6 EHT99597.1 - 0.24 11.0 10.9 0.49 10.0 10.9 1.5 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF1192 PF06698.11 EHT99597.1 - 0.26 11.4 9.2 0.62 10.2 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) FapA PF03961.13 EHT99597.1 - 0.33 9.5 1.9 0.4 9.2 1.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A OmpH PF03938.14 EHT99597.1 - 0.36 11.2 8.0 0.47 10.8 8.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) zf-IS66 PF13005.7 EHT99597.1 - 0.39 11.1 1.9 1.2 9.6 1.9 1.8 1 0 0 1 1 1 0 zinc-finger binding domain of transposase IS66 DUF4446 PF14584.6 EHT99597.1 - 0.49 10.4 3.2 0.47 10.4 1.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) G-gamma PF00631.22 EHT99597.1 - 0.55 10.3 3.7 4.4 7.4 0.0 2.6 2 1 1 3 3 2 0 GGL domain USP8_interact PF08941.10 EHT99597.1 - 0.62 9.9 4.4 1.3 8.8 4.4 1.5 1 1 0 1 1 1 0 USP8 interacting SlyX PF04102.12 EHT99597.1 - 0.72 10.5 10.3 5.1e+02 1.4 10.3 2.7 1 1 0 1 1 1 0 SlyX TMF_DNA_bd PF12329.8 EHT99597.1 - 0.78 9.8 9.1 1.3 9.0 0.7 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF641 PF04859.12 EHT99597.1 - 1.2 9.5 8.1 0.49 10.7 1.8 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) MerR-DNA-bind PF09278.11 EHT99597.1 - 5.2 7.7 13.4 5.9 7.5 2.2 2.6 2 1 0 2 2 2 0 MerR, DNA binding ZapB PF06005.12 EHT99597.1 - 5.6 7.5 10.6 49 4.5 9.3 2.5 1 1 0 1 1 1 0 Cell division protein ZapB HAUS6_N PF14661.6 EHT99597.1 - 6.1 6.4 8.9 16 5.0 8.9 1.7 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus FdhE PF04216.12 EHT99597.1 - 6.5 6.5 8.5 27 4.5 8.8 1.6 1 1 0 1 1 1 0 Protein involved in formate dehydrogenase formation TnpB_IS66 PF05717.13 EHT99598.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHT99599.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT99599.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT99599.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT99599.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix DDE_Tnp_ISL3 PF01610.17 EHT99600.1 - 2.5e-34 119.1 0.3 2.2e-19 70.1 0.0 2.2 2 0 0 2 2 2 2 Transposase zf-ISL3 PF14690.6 EHT99600.1 - 1.6e-06 28.6 7.4 1.6e-06 28.6 7.4 2.1 2 0 0 2 2 1 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HTH_29 PF13551.6 EHT99600.1 - 1.5e-05 24.9 0.8 4.4e-05 23.4 0.1 2.2 2 0 0 2 2 2 1 Winged helix-turn helix HTH_17 PF12728.7 EHT99600.1 - 0.00018 21.6 0.0 0.00079 19.6 0.0 2.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_7 PF02796.15 EHT99600.1 - 0.00032 20.7 0.5 0.0059 16.7 0.2 2.8 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 EHT99600.1 - 0.0042 16.8 3.7 0.019 14.7 0.5 3.4 3 0 0 3 3 3 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 EHT99600.1 - 0.0096 15.6 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 EHT99600.1 - 0.027 14.3 0.2 0.093 12.5 0.2 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_AlpA PF05930.12 EHT99600.1 - 0.027 14.3 0.0 0.07 13.0 0.0 1.6 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) MerR PF00376.23 EHT99600.1 - 0.032 14.0 0.1 0.098 12.4 0.1 1.9 1 0 0 1 1 1 0 MerR family regulatory protein HTH_28 PF13518.6 EHT99600.1 - 0.044 13.9 0.3 0.044 13.9 0.3 3.7 5 0 0 5 5 4 0 Helix-turn-helix domain HTH_IclR PF09339.10 EHT99600.1 - 0.051 13.4 0.0 0.34 10.7 0.0 2.4 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_AsnC-type PF13404.6 EHT99600.1 - 0.14 12.0 1.8 3.6 7.5 0.1 2.9 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Resolvase PF00239.21 EHT99601.1 - 1.6e-41 141.8 0.0 2.2e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_7 PF02796.15 EHT99601.1 - 0.00032 20.7 0.0 0.00064 19.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase TetR_N PF00440.23 EHT99601.1 - 0.005 16.6 0.0 0.63 9.9 0.0 2.4 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_8 PF02954.19 EHT99601.1 - 0.0068 16.2 0.4 0.27 11.1 0.0 2.4 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family HTH_17 PF12728.7 EHT99601.1 - 0.012 15.7 0.0 0.057 13.6 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_11 PF08279.12 EHT99601.1 - 0.025 14.5 0.0 0.057 13.4 0.0 1.6 1 0 0 1 1 1 0 HTH domain MarR_2 PF12802.7 EHT99601.1 - 0.045 13.6 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 MarR family HTH_29 PF13551.6 EHT99601.1 - 0.046 13.7 0.1 0.35 10.9 0.0 2.4 3 0 0 3 3 3 0 Winged helix-turn helix HTH_Tnp_1 PF01527.20 EHT99601.1 - 0.051 13.9 0.0 0.17 12.2 0.0 1.8 2 0 0 2 2 2 0 Transposase HTH_5 PF01022.20 EHT99601.1 - 0.058 13.3 0.0 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 EHT99601.1 - 0.061 13.4 0.1 0.23 11.5 0.1 2.2 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.6 EHT99601.1 - 0.068 13.3 0.3 0.19 11.9 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain AsnC_trans_reg PF01037.21 EHT99602.1 - 6.6e-22 77.3 0.1 9.3e-22 76.8 0.1 1.2 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 EHT99602.1 - 4.3e-16 58.2 0.3 8.1e-16 57.3 0.2 1.5 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 EHT99602.1 - 3.8e-13 49.0 0.4 6e-13 48.4 0.4 1.3 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_20 PF12840.7 EHT99602.1 - 0.00084 19.4 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 EHT99602.1 - 0.0094 15.9 0.1 0.017 15.1 0.1 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain DDRGK PF09756.9 EHT99602.1 - 0.017 14.7 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 DDRGK domain DUF4223 PF13978.6 EHT99602.1 - 0.13 12.2 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4223) SLH PF00395.20 EHT99602.1 - 0.17 11.9 0.0 3 7.9 0.0 2.6 3 0 0 3 3 3 0 S-layer homology domain EamA PF00892.20 EHT99603.1 - 1.1e-47 161.7 50.6 1.3e-26 93.4 21.6 2.0 2 0 0 2 2 2 2 EamA-like transporter family DUF4579 PF15158.6 EHT99603.1 - 2.1 8.0 6.5 8.5 6.1 1.3 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4579) DUF3188 PF11384.8 EHT99603.1 - 8.3 6.2 12.5 20 5.0 0.0 5.1 5 0 0 5 5 5 0 Protein of unknown function (DUF3188) TniQ PF06527.11 EHT99604.1 - 1.8e-11 44.9 0.1 3.3e-11 44.1 0.1 1.4 1 0 0 1 1 1 1 TniQ TetR_C_11 PF16859.5 EHT99604.1 - 0.06 13.7 0.1 0.14 12.5 0.1 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TniB PF05621.11 EHT99605.1 - 9.8e-78 259.9 0.0 1.2e-77 259.6 0.0 1.1 1 0 0 1 1 1 1 Bacterial TniB protein AAA_22 PF13401.6 EHT99605.1 - 3.1e-14 53.4 0.0 4.8e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EHT99605.1 - 0.0018 18.7 0.0 0.006 17.0 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_32 PF13654.6 EHT99605.1 - 0.052 12.3 0.0 0.1 11.3 0.0 1.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EHT99605.1 - 0.058 12.9 0.0 0.82 9.2 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 EHT99605.1 - 0.097 13.1 0.1 0.8 10.1 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 EHT99605.1 - 0.11 11.9 0.0 0.59 9.4 0.0 1.9 2 0 0 2 2 2 0 KaiC Mu-transpos_C PF09299.11 EHT99606.1 - 3.6e-13 49.3 0.1 8.4e-13 48.1 0.1 1.6 1 0 0 1 1 1 1 Mu transposase, C-terminal Herpes_UL56 PF04534.12 EHT99606.1 - 0.053 13.0 0.1 0.088 12.3 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus UL56 protein rve PF00665.26 EHT99607.1 - 6.4e-19 68.3 0.0 2.5e-18 66.4 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain HTH_28 PF13518.6 EHT99607.1 - 3e-10 40.1 0.9 7.5e-10 38.8 0.9 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 EHT99607.1 - 6.9e-06 26.0 0.6 1.8e-05 24.7 0.6 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 EHT99607.1 - 0.00057 19.6 0.8 0.0012 18.6 0.8 1.6 1 0 0 1 1 1 1 Homeodomain-like domain DDE_3 PF13358.6 EHT99607.1 - 0.04 13.7 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_8 PF02954.19 EHT99607.1 - 0.07 12.9 0.5 0.14 11.9 0.5 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family Resolvase PF00239.21 EHT99608.1 - 9.6e-28 97.1 1.0 2.1e-27 96.0 1.0 1.6 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_7 PF02796.15 EHT99608.1 - 0.014 15.5 0.6 0.068 13.3 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 EHT99608.1 - 0.016 15.0 0.1 0.047 13.5 0.1 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_3 PF01381.22 EHT99608.1 - 1 9.5 5.8 1.7 8.7 0.2 2.6 2 0 0 2 2 2 0 Helix-turn-helix IAT_beta PF11924.8 EHT99609.1 - 1.7e-111 372.1 1.4 6.7e-111 370.1 0.6 2.4 2 0 0 2 2 2 1 Inverse autotransporter, beta-domain Invasin_D3 PF09134.10 EHT99609.1 - 1.9e-46 156.3 105.4 8.8e-17 61.2 9.1 7.2 6 1 1 7 7 7 5 Invasin, domain 3 DUF823 PF05689.11 EHT99609.1 - 4.7e-40 137.4 14.1 6.5e-40 136.9 0.2 4.3 2 1 2 4 4 4 1 Salmonella repeat of unknown function (DUF823) Filamin PF00630.19 EHT99609.1 - 2.4e-21 76.5 8.9 0.0028 18.4 0.0 6.3 7 0 0 7 7 6 4 Filamin/ABP280 repeat Arrestin_C PF02752.22 EHT99609.1 - 1e-12 48.6 0.3 1.4 9.4 0.0 5.7 5 0 0 5 5 5 4 Arrestin (or S-antigen), C-terminal domain DUF824 PF05688.11 EHT99609.1 - 8.6e-11 41.5 8.5 2.5 8.0 0.2 7.3 9 0 0 9 9 9 5 Salmonella repeat of unknown function (DUF824) Big_1 PF02369.16 EHT99609.1 - 2.1e-09 37.2 84.7 0.069 13.2 6.7 9.1 8 1 1 9 9 9 5 Bacterial Ig-like domain (group 1) He_PIG PF05345.12 EHT99609.1 - 3.4e-06 27.1 40.9 0.36 11.1 1.2 7.4 6 0 0 6 6 6 4 Putative Ig domain DUF4442 PF14539.6 EHT99609.1 - 0.0025 18.0 15.5 8.5 6.5 0.3 4.8 4 0 0 4 4 4 4 Domain of unknown function (DUF4442) LysM PF01476.20 EHT99609.1 - 0.0046 17.0 0.0 0.012 15.7 0.0 1.8 1 0 0 1 1 1 1 LysM domain PLDc PF00614.22 EHT99609.1 - 0.027 14.7 3.0 1.7e+02 2.6 0.0 4.6 5 0 0 5 5 4 0 Phospholipase D Active site motif PurS PF02700.14 EHT99609.1 - 0.05 13.8 8.8 74 3.6 0.1 5.2 5 0 0 5 5 5 0 Phosphoribosylformylglycinamidine (FGAM) synthase ZirS_C PF16583.5 EHT99609.1 - 0.17 11.4 29.4 0.83 9.2 3.1 5.2 2 1 1 5 5 5 0 Zinc-regulated secreted antivirulence protein C-terminal domain Macoilin PF09726.9 EHT99609.1 - 1.2 7.6 5.3 3 6.3 5.3 1.6 1 0 0 1 1 1 0 Macoilin family Phage_tube PF04985.14 EHT99609.1 - 2.2 8.0 21.3 12 5.6 0.4 5.3 4 1 1 5 5 5 0 Phage tail tube protein FII NifU_N PF01592.16 EHT99609.1 - 6.5 6.9 17.1 29 4.8 1.0 4.7 1 1 3 4 4 4 0 NifU-like N terminal domain rve_2 PF13333.6 EHT99610.1 - 6.7e-13 48.6 2.6 7.8e-13 48.4 2.6 1.1 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 EHT99610.1 - 7.1e-05 22.5 0.1 8.5e-05 22.3 0.1 1.1 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.6 EHT99611.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHT99611.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHT99611.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHT99611.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHT99611.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHT99611.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHT99611.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHT99611.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 RicinB_lectin_2 PF14200.6 EHT99612.1 - 0.0045 17.7 0.0 0.0079 16.9 0.0 1.5 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like Amidase_2 PF01510.25 EHT99613.1 - 1.1e-22 80.9 0.0 1.7e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase PG_binding_1 PF01471.18 EHT99613.1 - 0.00033 20.8 0.0 0.00073 19.7 0.0 1.6 1 0 0 1 1 1 1 Putative peptidoglycan binding domain GHL10 PF02638.15 EHT99614.1 - 7.9e-91 304.4 3.2 9.4e-91 304.1 3.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 GHL6 PF14871.6 EHT99614.1 - 0.0058 16.8 0.2 7.9 6.6 0.9 3.8 3 1 0 3 3 3 1 Hypothetical glycosyl hydrolase 6 Melibiase PF02065.18 EHT99614.1 - 0.006 15.6 0.0 0.0095 14.9 0.0 1.2 1 0 0 1 1 1 1 Melibiase Resolvase PF00239.21 EHT99615.1 - 1e-27 97.0 1.1 2.2e-27 96.0 1.1 1.6 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_7 PF02796.15 EHT99615.1 - 0.016 15.3 0.6 0.072 13.2 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 EHT99615.1 - 0.017 14.9 0.1 0.05 13.4 0.1 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_3 PF01381.22 EHT99615.1 - 1.1 9.3 5.8 1.8 8.7 0.2 2.5 2 0 0 2 2 2 0 Helix-turn-helix IncFII_repA PF02387.15 EHT99616.1 - 1.7e-27 96.4 0.1 2.3e-27 96.0 0.1 1.2 1 0 0 1 1 1 1 IncFII RepA protein family ParE_toxin PF05016.15 EHT99617.1 - 3.4e-15 56.4 0.2 3.7e-15 56.3 0.2 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE PP28 PF10252.9 EHT99617.1 - 0.015 15.8 3.1 0.027 14.9 3.1 1.3 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 DDE_Tnp_Tn3 PF01526.17 EHT99618.1 - 2.4e-147 490.8 0.0 2.8e-147 490.6 0.0 1.0 1 0 0 1 1 1 1 Tn3 transposase DDE domain HTH_Tnp_1 PF01527.20 EHT99620.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT99620.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT99620.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT99620.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHT99621.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHT99622.1 - 1.3e-97 326.7 3.8 3.8e-97 325.1 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT99622.1 - 3e-16 59.3 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT99622.1 - 1.4e-14 54.2 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT99622.1 - 8.8e-11 42.4 8.7 1.9e-10 41.4 8.7 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHT99622.1 - 0.023 14.5 5.9 0.036 13.8 5.9 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Phage_HK97_TLTM PF06120.11 EHT99622.1 - 0.028 13.6 1.5 0.054 12.7 1.5 1.4 1 0 0 1 1 1 0 Tail length tape measure protein FUSC PF04632.12 EHT99622.1 - 0.03 12.9 6.3 0.048 12.2 6.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Csm1_N PF18504.1 EHT99622.1 - 0.032 14.6 4.4 0.12 12.8 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Tho2 PF11262.8 EHT99622.1 - 0.044 13.0 0.5 0.074 12.2 0.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Exonuc_VII_L PF02601.15 EHT99622.1 - 0.096 12.2 2.0 0.12 11.9 0.7 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit ERM PF00769.19 EHT99622.1 - 0.14 11.9 9.9 0.23 11.2 9.9 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family UME PF08064.13 EHT99622.1 - 0.17 11.8 0.5 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain HalX PF08663.10 EHT99622.1 - 0.19 12.1 3.0 0.49 10.7 3.0 1.7 1 0 0 1 1 1 0 HalX domain LXG PF04740.12 EHT99622.1 - 0.29 10.8 2.3 1.1 9.0 0.3 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily Zn-ribbon_8 PF09723.10 EHT99622.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DHR10 PF18595.1 EHT99622.1 - 0.52 10.4 10.4 0.91 9.6 10.4 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF1192 PF06698.11 EHT99622.1 - 1 9.4 6.1 4 7.6 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) HAUS-augmin3 PF14932.6 EHT99622.1 - 4.2 6.9 7.3 9.3 5.7 7.3 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 SlyX PF04102.12 EHT99622.1 - 6.1 7.5 8.3 8.1 7.1 1.0 3.0 1 1 0 2 2 2 0 SlyX ACR_tran PF00873.19 EHT99623.1 - 0 1309.4 5.9 0 1309.2 5.9 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 EHT99623.1 - 4.3e-11 42.3 31.4 2.9e-07 29.7 10.0 3.2 3 0 0 3 3 3 3 MMPL family SecD_SecF PF02355.16 EHT99623.1 - 0.0066 15.9 25.3 0.013 14.9 1.9 2.3 2 0 0 2 2 2 2 Protein export membrane protein ArsC PF03960.15 EHT99625.1 - 7.7e-14 51.5 0.0 1.2e-13 50.8 0.0 1.4 1 1 0 1 1 1 1 ArsC family Glutaredoxin PF00462.24 EHT99625.1 - 0.0098 16.1 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin UBA_4 PF14555.6 EHT99625.1 - 0.11 12.4 0.1 3.4 7.6 0.0 2.3 2 0 0 2 2 2 0 UBA-like domain Dehalogenase PF13486.6 EHT99625.1 - 0.16 11.3 0.0 0.29 10.5 0.0 1.4 1 1 0 1 1 1 0 Reductive dehalogenase subunit Peptidase_M20 PF01546.28 EHT99626.1 - 1.1e-43 149.3 0.0 1.4e-43 149.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EHT99626.1 - 3.8e-24 84.7 0.0 8.3e-24 83.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EHT99626.1 - 0.0078 15.9 0.0 0.039 13.6 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M18 PF02127.15 EHT99626.1 - 0.037 12.8 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 Aminopeptidase I zinc metalloprotease (M18) UPF0370 PF13980.6 EHT99627.1 - 1.2e-31 108.5 10.7 1.3e-31 108.3 10.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0370) DUF4051 PF13260.6 EHT99627.1 - 0.0027 17.4 0.9 0.0032 17.2 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4051) Phage_holin_5_2 PF16079.5 EHT99627.1 - 0.056 13.8 0.0 0.062 13.6 0.0 1.1 1 0 0 1 1 1 0 Phage holin family Hol44, in holin superfamily V Abhydrolase_2 PF02230.16 EHT99628.1 - 4.3e-34 118.2 0.1 5.6e-34 117.8 0.1 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.18 EHT99628.1 - 2.5e-09 37.0 0.0 3.6e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EHT99628.1 - 5e-09 35.9 3.2 0.0011 18.5 0.9 2.1 1 1 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 EHT99628.1 - 0.0025 17.5 0.1 0.0027 17.4 0.1 1.2 1 0 0 1 1 1 1 Putative esterase DUF2920 PF11144.8 EHT99628.1 - 0.037 13.2 0.0 0.052 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Helicase_RecD PF05127.14 EHT99629.1 - 2e-40 138.5 3.2 1.6e-38 132.3 1.0 3.1 3 1 0 3 3 3 1 Helicase tRNA_bind_3 PF17176.4 EHT99629.1 - 5.1e-29 101.0 9.6 5.1e-29 101.0 9.6 2.4 2 0 0 2 2 2 1 tRNA-binding domain GNAT_acetyltr_2 PF13718.6 EHT99629.1 - 2.1e-22 79.7 0.1 6.7e-15 55.1 0.0 2.2 1 1 1 2 2 2 2 GNAT acetyltransferase 2 DUF1726 PF08351.11 EHT99629.1 - 1.5e-07 31.2 0.0 3.5e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) Acetyltransf_7 PF13508.7 EHT99629.1 - 9.2e-06 26.0 0.0 6.5e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EHT99629.1 - 0.00013 21.9 0.0 0.00027 20.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AAA_30 PF13604.6 EHT99629.1 - 0.00016 21.5 1.3 0.00035 20.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain Acetyltransf_1 PF00583.25 EHT99629.1 - 0.0033 17.7 0.1 0.0074 16.5 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 EHT99629.1 - 0.2 11.8 0.1 0.46 10.6 0.1 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Zn_peptidase PF04228.13 EHT99630.1 - 5.5e-134 446.1 1.1 6.2e-134 446.0 1.1 1.0 1 0 0 1 1 1 1 Putative neutral zinc metallopeptidase Aspzincin_M35 PF14521.6 EHT99630.1 - 0.024 15.2 0.0 0.045 14.3 0.0 1.5 1 0 0 1 1 1 0 Lysine-specific metallo-endopeptidase SAICAR_synt PF01259.18 EHT99631.1 - 2.5e-60 204.2 0.0 2.9e-60 204.0 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Peptidase_M42 PF05343.14 EHT99631.1 - 0.0094 15.0 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase IF2_N PF04760.15 EHT99631.1 - 0.068 13.0 0.1 8.3 6.3 0.0 2.6 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region Lipoprotein_18 PF06804.11 EHT99632.1 - 3.8e-109 364.6 1.7 4.4e-109 364.4 1.7 1.0 1 0 0 1 1 1 1 NlpB/DapX lipoprotein FlgD_ig PF13860.6 EHT99632.1 - 0.00098 18.9 0.3 0.043 13.7 0.0 2.7 2 0 0 2 2 2 1 FlgD Ig-like domain DHDPS PF00701.22 EHT99633.1 - 1.1e-114 382.0 0.1 1.3e-114 381.8 0.1 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family YjgF_endoribonc PF14588.6 EHT99633.1 - 0.099 12.8 0.4 0.4 10.8 0.1 2.0 1 1 1 2 2 2 0 YjgF/chorismate_mutase-like, putative endoribonuclease ACT_6 PF13740.6 EHT99634.1 - 3.7e-25 87.7 0.3 7.1e-24 83.6 0.1 2.1 2 0 0 2 2 2 1 ACT domain ACT_4 PF13291.6 EHT99634.1 - 0.00077 20.0 0.0 0.061 13.9 0.0 2.2 2 0 0 2 2 2 1 ACT domain ACT PF01842.25 EHT99634.1 - 0.018 14.8 0.0 5.3 6.9 0.0 2.3 2 0 0 2 2 2 0 ACT domain AhpC-TSA PF00578.21 EHT99635.1 - 4.3e-39 133.2 0.0 5.1e-39 133.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EHT99635.1 - 9e-28 96.8 0.0 1.1e-27 96.6 0.0 1.0 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.14 EHT99635.1 - 3.6e-06 26.9 0.0 5.7e-06 26.3 0.0 1.3 1 1 0 1 1 1 1 SCO1/SenC AhpC-TSA_2 PF13911.6 EHT99635.1 - 2e-05 24.7 0.0 2.6e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF899 PF05988.12 EHT99635.1 - 0.0029 17.2 0.0 0.0033 17.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) GSHPx PF00255.19 EHT99635.1 - 0.0034 16.9 0.0 0.0058 16.2 0.0 1.3 1 1 0 1 1 1 1 Glutathione peroxidase AI-2E_transport PF01594.16 EHT99636.1 - 9.6e-78 261.6 39.9 1.1e-77 261.4 39.9 1.0 1 0 0 1 1 1 1 AI-2E family transporter DUF4577 PF15145.6 EHT99636.1 - 0.16 12.0 0.1 0.16 12.0 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4577) Glyco_hydro_127 PF07944.12 EHT99637.1 - 7.8e-170 565.8 0.1 9e-170 565.6 0.1 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 MFS_2 PF13347.6 EHT99638.1 - 7.6e-31 107.1 18.0 8.4e-31 107.0 18.0 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 EHT99638.1 - 3.6e-05 22.9 20.3 3.6e-05 22.9 20.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2070 PF09843.9 EHT99638.1 - 0.93 7.7 13.7 1.3 7.2 13.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Leu_leader PF08054.11 EHT99638.1 - 1.1 8.9 6.2 2.5 7.7 0.9 2.7 2 0 0 2 2 2 0 Leucine operon leader peptide MFS_2 PF13347.6 EHT99639.1 - 5.8e-47 160.2 11.6 6.4e-47 160.1 11.6 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1_like PF12832.7 EHT99639.1 - 0.00034 19.6 2.7 0.00051 19.0 1.6 1.9 1 1 0 1 1 1 1 MFS_1 like family HTH_18 PF12833.7 EHT99640.1 - 8.8e-17 61.2 0.2 1.7e-16 60.3 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 EHT99640.1 - 2.3e-11 43.5 0.1 2.9e-09 36.8 0.0 2.7 3 0 0 3 3 3 1 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding PF02311.19 EHT99640.1 - 3.8e-07 30.1 1.3 1e-06 28.7 1.3 1.8 1 1 0 1 1 1 1 AraC-like ligand binding domain Cupin_2 PF07883.11 EHT99640.1 - 8.3e-05 22.2 0.1 0.00014 21.5 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 EHT99640.1 - 0.18 11.5 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) GGDEF PF00990.21 EHT99641.1 - 2.7e-42 144.2 0.1 5.1e-42 143.4 0.1 1.5 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain dCache_1 PF02743.18 EHT99641.1 - 6e-21 75.4 0.8 9.5e-21 74.7 0.2 1.6 2 0 0 2 2 2 1 Cache domain GGDEF_2 PF17853.1 EHT99641.1 - 6.6e-07 29.6 0.1 2e-06 28.0 0.1 1.8 1 0 0 1 1 1 1 GGDEF-like domain dCache_2 PF08269.11 EHT99641.1 - 0.15 11.2 0.0 0.61 9.2 0.0 1.8 2 0 0 2 2 2 0 Cache domain SHP PF03579.13 EHT99641.1 - 6.9 6.7 6.1 1.2 9.2 1.8 1.9 2 0 0 2 2 2 0 Small hydrophobic protein Metallophos PF00149.28 EHT99642.1 - 1.4e-18 68.1 0.0 1.9e-18 67.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EHT99642.1 - 9.3e-11 42.2 0.7 4.2e-10 40.1 0.7 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ABC_tran PF00005.27 EHT99643.1 - 3.2e-34 118.4 0.0 4.9e-34 117.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EHT99643.1 - 8.7e-10 38.9 0.0 0.00039 20.3 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system TOBE_2 PF08402.10 EHT99643.1 - 3.5e-05 23.9 0.1 0.00068 19.7 0.0 2.8 3 0 0 3 3 3 1 TOBE domain AAA_16 PF13191.6 EHT99643.1 - 0.00022 21.6 0.7 0.0006 20.2 0.7 1.7 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 EHT99643.1 - 0.00053 19.5 0.1 0.0064 15.9 0.1 2.0 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 EHT99643.1 - 0.0012 18.9 0.0 0.0017 18.3 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 EHT99643.1 - 0.0048 17.3 0.5 0.065 13.7 0.5 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EHT99643.1 - 0.031 14.5 0.3 0.18 12.0 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EHT99643.1 - 0.037 14.2 0.7 6.2 7.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 EHT99643.1 - 0.038 13.9 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase G-alpha PF00503.20 EHT99643.1 - 0.058 12.5 0.0 0.1 11.7 0.0 1.3 1 1 0 1 1 1 0 G-protein alpha subunit AAA_22 PF13401.6 EHT99643.1 - 0.062 13.6 1.0 0.22 11.8 0.6 2.0 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EHT99643.1 - 0.068 13.7 0.0 0.28 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EHT99643.1 - 0.12 12.2 0.1 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.14 EHT99643.1 - 0.13 12.3 0.1 0.4 10.7 0.1 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 EHT99643.1 - 0.14 12.4 0.2 1.8 8.9 0.2 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit BPD_transp_1 PF00528.22 EHT99644.1 - 1.9e-13 50.6 11.3 1.9e-13 50.6 11.3 2.2 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Bac_export_3 PF01313.19 EHT99644.1 - 0.095 12.6 0.6 0.095 12.6 0.6 4.2 6 0 0 6 6 6 0 Bacterial export proteins, family 3 Mannosyl_trans4 PF15971.5 EHT99644.1 - 0.43 10.4 7.7 5.8 6.7 1.7 2.9 2 2 0 2 2 2 0 DolP-mannose mannosyltransferase Sigma_reg_N PF13800.6 EHT99644.1 - 1.1 9.6 3.6 12 6.3 0.4 2.9 3 0 0 3 3 3 0 Sigma factor regulator N-terminal BPD_transp_1 PF00528.22 EHT99645.1 - 6.1e-17 62.0 12.3 6.1e-17 62.0 12.3 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Peripla_BP_3 PF13377.6 EHT99646.1 - 4.8e-27 95.3 1.1 6.6e-27 94.9 0.2 1.7 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 EHT99646.1 - 2.5e-25 89.4 0.2 3.3e-25 89.1 0.2 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 EHT99646.1 - 4.8e-09 36.2 0.0 1.1e-08 35.0 0.0 1.6 1 1 0 1 1 1 1 Periplasmic binding protein domain LacI PF00356.21 EHT99646.1 - 5e-07 29.4 0.0 2.4e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family Peripla_BP_6 PF13458.6 EHT99646.1 - 0.00047 19.9 0.1 0.00079 19.2 0.1 1.3 1 0 0 1 1 1 1 Periplasmic binding protein VRP1 PF03538.14 EHT99646.1 - 0.02 14.3 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Salmonella virulence plasmid 28.1kDa A protein DrsE PF02635.15 EHT99647.1 - 2.6e-10 40.7 0.0 3.6e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 DsrE/DsrF-like family Peptidase_M48 PF01435.18 EHT99648.1 - 4.9e-27 95.0 0.2 8.6e-27 94.2 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M48 TPR_19 PF14559.6 EHT99648.1 - 4.4e-10 39.9 12.5 4.3e-07 30.3 2.1 4.1 1 1 4 5 5 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EHT99648.1 - 8.4e-05 22.7 3.9 0.014 15.6 0.4 3.4 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EHT99648.1 - 0.00014 22.3 11.6 0.29 12.1 0.2 5.3 3 1 1 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EHT99648.1 - 0.00076 19.4 1.4 1.4 9.2 0.1 4.8 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EHT99648.1 - 0.0051 17.4 1.4 6.1 7.7 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 EHT99648.1 - 0.011 15.8 1.8 0.4 10.9 0.1 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EHT99648.1 - 0.04 14.0 0.0 0.15 12.2 0.0 2.0 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat DUF4157 PF13699.6 EHT99648.1 - 0.065 13.5 2.4 0.1 12.9 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4157) TPR_16 PF13432.6 EHT99648.1 - 0.15 12.8 11.5 1.6 9.5 1.1 4.8 4 1 1 5 5 4 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 EHT99648.1 - 0.18 11.7 3.8 0.23 11.4 0.4 2.4 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal Mononeg_mRNAcap PF14318.6 EHT99648.1 - 0.18 11.0 0.1 0.36 10.0 0.1 1.4 1 0 0 1 1 1 0 Mononegavirales mRNA-capping region V TPR_17 PF13431.6 EHT99648.1 - 1.8 9.1 7.9 40 4.9 0.1 4.4 3 1 1 4 4 3 0 Tetratricopeptide repeat ArsC PF03960.15 EHT99649.1 - 6.4e-20 70.9 0.1 7.3e-20 70.8 0.1 1.1 1 0 0 1 1 1 1 ArsC family Glutaredoxin PF00462.24 EHT99649.1 - 0.011 16.0 0.0 0.051 13.8 0.0 1.9 1 1 0 2 2 2 0 Glutaredoxin DUF1687 PF07955.11 EHT99649.1 - 0.047 14.2 0.0 0.25 11.8 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1687) Bac_DnaA PF00308.18 EHT99650.1 - 4.3e-14 52.9 0.0 5.4e-14 52.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial dnaA protein Xan_ur_permease PF00860.20 EHT99651.1 - 1.3e-107 359.9 41.1 1.8e-107 359.4 41.1 1.2 1 0 0 1 1 1 1 Permease family DUF5463 PF17551.2 EHT99651.1 - 0.14 12.0 0.0 0.41 10.6 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5463) UPRTase PF14681.6 EHT99652.1 - 6e-65 218.6 0.0 6.7e-65 218.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EHT99652.1 - 2.3e-13 50.0 0.3 3.4e-13 49.4 0.3 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.6 EHT99652.1 - 0.052 13.6 0.0 0.084 12.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain AIRS_C PF02769.22 EHT99653.1 - 1.4e-38 132.5 0.0 2.2e-38 131.8 0.0 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 EHT99653.1 - 1.8e-15 57.3 0.7 3.3e-15 56.5 0.7 1.5 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Formyl_trans_N PF00551.19 EHT99654.1 - 1.3e-64 217.3 0.0 1.5e-64 217.1 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase ABC_tran PF00005.27 EHT99655.1 - 7.5e-32 110.7 0.0 1.1e-31 110.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EHT99655.1 - 6.2e-11 42.7 0.5 0.00024 21.0 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EHT99655.1 - 3.5e-06 27.3 0.0 2e-05 24.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EHT99655.1 - 6.9e-05 23.3 0.6 0.00039 20.8 0.6 2.0 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 EHT99655.1 - 0.00017 21.1 0.1 0.0073 15.8 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EHT99655.1 - 0.00028 20.8 0.0 0.00061 19.7 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 EHT99655.1 - 0.00043 20.9 0.0 0.00083 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EHT99655.1 - 0.00052 19.7 0.0 0.0014 18.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EHT99655.1 - 0.00071 19.4 0.0 0.0023 17.7 0.0 1.5 1 1 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 EHT99655.1 - 0.00099 19.1 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 EHT99655.1 - 0.012 15.3 0.1 0.88 9.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EHT99655.1 - 0.016 15.4 0.0 0.028 14.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EHT99655.1 - 0.027 14.5 0.1 0.51 10.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 EHT99655.1 - 0.033 13.8 0.1 0.11 12.1 0.0 1.8 2 1 0 2 2 2 0 AAA domain TniB PF05621.11 EHT99655.1 - 0.036 13.5 0.1 0.35 10.2 0.0 2.3 1 1 1 2 2 2 0 Bacterial TniB protein AAA PF00004.29 EHT99655.1 - 0.048 14.1 0.0 1.6 9.2 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 EHT99655.1 - 0.049 12.4 0.0 8.2 5.1 0.0 2.3 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_24 PF13479.6 EHT99655.1 - 0.058 13.1 0.0 0.6 9.8 0.0 2.1 2 1 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.15 EHT99655.1 - 0.17 10.7 0.1 0.4 9.4 0.0 1.6 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_18 PF13238.6 EHT99655.1 - 0.18 12.4 0.0 0.57 10.7 0.0 1.8 2 1 0 2 2 2 0 AAA domain BPD_transp_1 PF00528.22 EHT99656.1 - 1.9e-18 66.8 14.0 1.9e-18 66.8 14.0 2.8 2 1 1 3 3 3 1 Binding-protein-dependent transport system inner membrane component MLTD_N PF06474.12 EHT99656.1 - 0.12 12.6 0.1 0.49 10.6 0.1 2.1 1 0 0 1 1 1 0 MltD lipid attachment motif DUF4055 PF13264.6 EHT99656.1 - 0.12 12.5 2.0 0.24 11.6 2.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) DUF3333 PF11812.8 EHT99656.1 - 0.13 12.5 0.0 0.13 12.5 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3333) G6PD_bact PF10786.9 EHT99656.1 - 0.15 11.6 1.2 0.23 11.0 1.2 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) DUF3413 PF11893.8 EHT99656.1 - 0.19 10.9 4.5 4.1 6.5 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3413) DUF3357 PF11837.8 EHT99656.1 - 2.8 8.5 5.5 8.7 6.9 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF3357) BPD_transp_1 PF00528.22 EHT99657.1 - 2.1e-13 50.4 18.2 2.1e-13 50.4 18.2 3.2 2 1 1 3 3 3 2 Binding-protein-dependent transport system inner membrane component DUF3261 PF11659.8 EHT99657.1 - 0.0061 16.4 0.1 0.018 14.9 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3261) DUF3262 PF11660.8 EHT99657.1 - 4.3 7.8 8.9 14 6.2 0.7 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3262) PP_kinase_C_1 PF17941.1 EHT99658.1 - 2.3e-73 245.2 0.2 4e-73 244.5 0.2 1.4 1 0 0 1 1 1 1 Polyphosphate kinase C-terminal domain 1 PP_kinase_C PF13090.6 EHT99658.1 - 9.6e-69 230.3 3.0 1.9e-68 229.3 0.9 2.1 2 0 0 2 2 2 1 Polyphosphate kinase C-terminal domain 2 PP_kinase PF02503.17 EHT99658.1 - 1.7e-45 155.1 0.3 2.9e-45 154.4 0.3 1.4 1 0 0 1 1 1 1 Polyphosphate kinase middle domain PP_kinase_N PF13089.6 EHT99658.1 - 5.5e-32 110.3 0.7 5.5e-32 110.3 0.7 2.0 2 0 0 2 2 2 1 Polyphosphate kinase N-terminal domain PLDc_2 PF13091.6 EHT99658.1 - 3.6e-16 59.3 0.9 1.1e-09 38.3 0.2 3.1 2 1 0 2 2 2 2 PLD-like domain Pyr_redox PF00070.27 EHT99658.1 - 0.039 14.5 0.1 0.25 11.9 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ppx-GppA PF02541.16 EHT99659.1 - 1.2e-96 323.5 0.0 1.7e-96 323.0 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family HD PF01966.22 EHT99659.1 - 0.034 14.4 0.0 0.079 13.2 0.0 1.6 1 0 0 1 1 1 0 HD domain FtsA PF14450.6 EHT99659.1 - 0.061 13.8 0.0 1.6 9.2 0.0 2.6 2 0 0 2 2 2 0 Cell division protein FtsA EutK_C PF16365.5 EHT99659.1 - 0.099 12.7 0.2 2.1 8.4 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilization protein EutK C-terminus TehB PF03848.14 EHT99660.1 - 3.4e-81 271.3 0.0 3.8e-81 271.1 0.0 1.0 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_25 PF13649.6 EHT99660.1 - 9e-11 42.3 0.0 1.7e-10 41.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EHT99660.1 - 7.3e-07 29.2 0.0 9e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EHT99660.1 - 1.7e-06 28.6 0.0 2.8e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EHT99660.1 - 4.1e-05 24.2 0.0 6.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EHT99660.1 - 4.8e-05 23.2 0.0 7.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EHT99660.1 - 7e-05 22.4 0.0 0.0001 21.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 EHT99660.1 - 0.049 13.2 0.0 0.1 12.2 0.0 1.4 1 1 1 2 2 2 0 Nodulation protein S (NodS) DUF2633 PF11119.8 EHT99661.1 - 3.6e-13 49.2 0.3 4.1e-13 49.0 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2633) Sigma_reg_N PF13800.6 EHT99661.1 - 0.033 14.5 0.1 0.038 14.3 0.1 1.0 1 0 0 1 1 1 0 Sigma factor regulator N-terminal OSTMP1 PF09777.9 EHT99661.1 - 0.092 12.1 0.1 0.094 12.1 0.1 1.0 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor DUF3328 PF11807.8 EHT99661.1 - 0.092 12.5 0.5 0.096 12.4 0.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) MgtE_N PF03448.17 EHT99662.1 - 2.6e-21 76.2 0.4 6.3e-21 74.9 0.4 1.7 1 0 0 1 1 1 1 MgtE intracellular N domain CBS PF00571.28 EHT99662.1 - 2.6e-09 37.4 1.1 0.00035 21.0 0.0 3.4 4 0 0 4 4 4 2 CBS domain MgtE PF01769.16 EHT99663.1 - 2.2e-27 95.9 10.3 2.2e-27 95.9 10.3 1.7 2 0 0 2 2 2 1 Divalent cation transporter ABA_GPCR PF12430.8 EHT99663.1 - 0.01 15.6 1.0 0.014 15.2 1.0 1.1 1 0 0 1 1 1 0 Abscisic acid G-protein coupled receptor DDE_3 PF13358.6 EHT99664.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHT99664.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHT99664.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHT99664.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHT99664.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHT99664.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHT99664.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHT99664.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 DUF4054 PF13262.6 EHT99666.1 - 4.9e-34 116.6 0.1 5.6e-34 116.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4054) PROCT PF08084.11 EHT99666.1 - 0.018 15.0 0.1 0.22 11.4 0.1 2.1 2 0 0 2 2 2 0 PROCT (NUC072) domain DUF3450 PF11932.8 EHT99667.1 - 0.00013 21.4 1.1 0.00016 21.1 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 EHT99667.1 - 0.0011 19.1 0.1 0.0014 18.9 0.1 1.1 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Filament PF00038.21 EHT99667.1 - 0.0017 18.0 0.2 0.002 17.8 0.2 1.0 1 0 0 1 1 1 1 Intermediate filament protein DUF641 PF04859.12 EHT99667.1 - 0.0035 17.7 0.1 0.0045 17.3 0.1 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) DUF4407 PF14362.6 EHT99667.1 - 0.018 14.4 0.6 0.02 14.3 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Phage_GP20 PF06810.11 EHT99667.1 - 0.02 14.7 1.3 0.029 14.2 1.3 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 Spc7 PF08317.11 EHT99667.1 - 0.021 13.7 0.4 0.025 13.5 0.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein UPF0242 PF06785.11 EHT99667.1 - 0.022 14.9 1.0 0.03 14.4 1.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Tho2 PF11262.8 EHT99667.1 - 0.025 13.8 0.2 0.032 13.4 0.2 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 BST2 PF16716.5 EHT99667.1 - 0.04 14.5 0.4 0.054 14.1 0.4 1.2 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 DUF1949 PF09186.11 EHT99667.1 - 0.057 13.3 1.2 28 4.7 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1949) AAA_13 PF13166.6 EHT99667.1 - 0.06 12.0 0.5 0.066 11.9 0.5 1.0 1 0 0 1 1 1 0 AAA domain DASH_Dad1 PF08649.10 EHT99667.1 - 0.069 13.4 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 DASH complex subunit Dad1 BCDHK_Adom3 PF10436.9 EHT99667.1 - 0.12 12.2 0.1 0.16 11.8 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase DUF2680 PF10925.8 EHT99667.1 - 1.3 9.0 5.2 0.35 10.9 1.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) DivIC PF04977.15 EHT99667.1 - 2.8 7.8 6.9 3 7.7 3.5 2.0 1 1 0 1 1 1 0 Septum formation initiator DUF2184 PF09950.9 EHT99669.1 - 7.8e-83 277.7 0.0 9.9e-83 277.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2184) HTH_Tnp_1 PF01527.20 EHT99671.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT99671.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT99671.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT99671.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHT99672.1 - 1.7e-39 133.8 0.0 2e-39 133.6 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHT99673.1 - 2.7e-97 325.7 4.0 1.2e-96 323.5 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT99673.1 - 3.3e-16 59.2 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT99673.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT99673.1 - 8.7e-11 42.4 9.0 1.9e-10 41.4 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Phage_HK97_TLTM PF06120.11 EHT99673.1 - 0.011 15.0 0.8 0.021 14.0 0.8 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHT99673.1 - 0.02 15.2 4.2 0.084 13.2 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain UME PF08064.13 EHT99673.1 - 0.032 14.1 0.3 20 5.1 0.0 3.1 2 1 1 3 3 3 0 UME (NUC010) domain Exonuc_VII_L PF02601.15 EHT99673.1 - 0.039 13.5 2.7 0.04 13.5 1.0 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Troponin PF00992.20 EHT99673.1 - 0.044 14.1 2.8 0.078 13.3 2.8 1.3 1 0 0 1 1 1 0 Troponin FUSC PF04632.12 EHT99673.1 - 0.048 12.2 7.4 0.077 11.5 7.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tho2 PF11262.8 EHT99673.1 - 0.049 12.8 0.6 0.081 12.1 0.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FAM184 PF15665.5 EHT99673.1 - 0.052 13.3 8.0 0.082 12.7 8.0 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B HalX PF08663.10 EHT99673.1 - 0.13 12.6 2.4 0.34 11.3 2.4 1.7 1 0 0 1 1 1 0 HalX domain LXG PF04740.12 EHT99673.1 - 0.14 11.8 2.8 0.35 10.5 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHT99673.1 - 0.19 11.5 11.1 0.31 10.8 11.1 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DHR10 PF18595.1 EHT99673.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Zn-ribbon_8 PF09723.10 EHT99673.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF1192 PF06698.11 EHT99673.1 - 0.54 10.4 5.3 3.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHT99673.1 - 0.82 8.9 3.0 1.2 8.3 3.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHT99673.1 - 2 8.0 8.1 4.3 6.8 8.1 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHT99673.1 - 4.2 7.7 8.6 8.7 6.7 8.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CREPT PF16566.5 EHT99673.1 - 5.9 7.1 8.7 2.7 8.1 5.6 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour SlyX PF04102.12 EHT99673.1 - 9.7 6.9 9.0 18 6.1 2.3 3.0 1 1 1 2 2 2 0 SlyX FaeA PF04703.12 EHT99674.1 - 7.2e-08 32.7 0.0 8.3e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 FaeA-like protein HTH_DeoR PF08220.12 EHT99674.1 - 0.0072 16.1 0.0 0.0092 15.7 0.0 1.2 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_23 PF13384.6 EHT99674.1 - 0.082 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Homeodomain-like domain Rrf2 PF02082.20 EHT99674.1 - 0.17 12.2 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator ABC_tran PF00005.27 EHT99675.1 - 4.7e-35 121.1 0.0 5.9e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EHT99675.1 - 9e-09 35.5 1.3 6.5e-06 26.2 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EHT99675.1 - 3e-05 23.6 0.1 0.002 17.6 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EHT99675.1 - 0.00031 21.2 0.3 0.00073 20.0 0.3 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 EHT99675.1 - 0.0035 17.1 0.4 0.065 12.9 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain KAP_NTPase PF07693.14 EHT99675.1 - 0.0082 15.4 0.0 0.0098 15.2 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain AAA_29 PF13555.6 EHT99675.1 - 0.0084 15.8 0.1 0.018 14.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Mg_chelatase PF01078.21 EHT99675.1 - 0.0093 15.4 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 EHT99675.1 - 0.014 15.3 0.2 0.024 14.5 0.2 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 EHT99675.1 - 0.037 13.8 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2867 PF11066.8 EHT99675.1 - 0.051 13.9 0.4 0.27 11.6 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2867) AAA_23 PF13476.6 EHT99675.1 - 0.065 13.7 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EHT99675.1 - 0.066 13.2 0.0 0.23 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 EHT99675.1 - 0.076 12.6 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_18 PF13238.6 EHT99675.1 - 0.084 13.4 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 EHT99675.1 - 0.14 12.1 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase FecCD PF01032.18 EHT99676.1 - 3.9e-88 295.4 41.6 4.9e-88 295.1 41.6 1.1 1 0 0 1 1 1 1 FecCD transport family ABC-3 PF00950.17 EHT99676.1 - 6.6e-07 29.1 26.0 6.6e-07 29.1 26.0 2.0 2 0 0 2 2 2 1 ABC 3 transport family DctQ PF04290.12 EHT99676.1 - 0.027 14.4 3.7 0.027 14.4 3.7 5.0 3 3 1 5 5 5 0 Tripartite ATP-independent periplasmic transporters, DctQ component Peripla_BP_2 PF01497.18 EHT99677.1 - 1e-38 133.3 0.1 1.2e-38 133.0 0.1 1.1 1 0 0 1 1 1 1 Periplasmic binding protein L51_S25_CI-B8 PF05047.16 EHT99677.1 - 0.098 12.6 0.1 3.3 7.7 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Arm-DNA-bind_3 PF13356.6 EHT99678.1 - 2.7e-18 66.1 0.0 6e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 Arm DNA-binding domain Phage_integrase PF00589.22 EHT99678.1 - 9e-13 48.4 0.1 2.1e-11 43.9 0.0 2.7 3 0 0 3 3 3 1 Phage integrase family SmpB PF01668.18 EHT99679.1 - 6.2e-56 188.3 0.1 7.1e-56 188.1 0.1 1.0 1 0 0 1 1 1 1 SmpB protein Polyketide_cyc PF03364.20 EHT99680.1 - 4.7e-33 114.2 0.0 5.4e-33 114.0 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 EHT99680.1 - 2.1e-09 37.8 0.0 2.4e-09 37.6 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF1857 PF08982.11 EHT99680.1 - 0.084 12.7 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1857) Ub-RnfH PF03658.14 EHT99681.1 - 1.8e-34 118.0 0.2 2e-34 117.8 0.2 1.0 1 0 0 1 1 1 1 RnfH family Ubiquitin ThiS PF02597.20 EHT99681.1 - 0.11 13.2 0.1 0.21 12.3 0.1 1.5 1 1 0 1 1 1 0 ThiS family SmpA_OmlA PF04355.13 EHT99682.1 - 1.8e-26 91.7 0.7 2.2e-26 91.4 0.7 1.1 1 0 0 1 1 1 1 SmpA / OmlA family DUF3696 PF12476.8 EHT99682.1 - 0.033 14.6 0.0 0.06 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3696) Sulfolobus_pRN PF05584.11 EHT99682.1 - 0.2 11.7 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 Sulfolobus plasmid regulatory protein SMC_N PF02463.19 EHT99683.1 - 4.7e-19 68.7 0.0 6.6e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EHT99683.1 - 4.9e-18 66.4 4.9 1.9e-16 61.2 4.9 2.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EHT99683.1 - 8.6e-06 25.4 0.0 1.9e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EHT99683.1 - 0.0017 18.1 0.1 0.0097 15.7 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 EHT99683.1 - 0.0037 17.8 5.0 0.95 10.0 0.0 3.5 3 1 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 EHT99683.1 - 0.0049 16.7 0.0 1.1 9.0 0.0 2.5 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EHT99683.1 - 0.0049 17.1 8.1 0.029 14.6 0.0 4.2 2 1 0 4 4 4 1 AAA domain Vps51 PF08700.11 EHT99683.1 - 0.067 13.3 0.2 0.067 13.3 0.2 2.8 3 1 0 3 3 3 0 Vps51/Vps67 NAD_kinase PF01513.21 EHT99684.1 - 7.2e-78 261.7 0.0 9.1e-78 261.4 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase GrpE PF01025.19 EHT99685.1 - 1.7e-50 171.0 4.4 2.3e-50 170.5 4.4 1.2 1 1 0 1 1 1 1 GrpE Baculo_PEP_C PF04513.12 EHT99685.1 - 0.011 15.8 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Focal_AT PF03623.13 EHT99685.1 - 0.015 15.3 0.9 0.99 9.4 0.2 2.3 1 1 1 2 2 2 0 Focal adhesion targeting region DUF4407 PF14362.6 EHT99685.1 - 0.018 14.4 6.1 0.024 14.0 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UDG PF03167.19 EHT99686.1 - 3.9e-27 95.1 0.0 5.5e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Gly_radical PF01228.21 EHT99687.1 - 4.1e-22 78.7 0.1 7.7e-22 77.8 0.0 1.5 2 0 0 2 2 2 1 Glycine radical DEAD PF00270.29 EHT99688.1 - 1e-46 158.9 0.0 2e-46 157.9 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EHT99688.1 - 1.7e-30 105.6 0.2 1.2e-28 99.6 0.1 2.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EHT99688.1 - 6.7e-08 32.7 0.0 1.2e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EHT99688.1 - 7.1e-05 23.2 0.1 0.00015 22.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EHT99688.1 - 0.015 15.5 0.1 0.065 13.5 0.0 2.1 1 1 1 2 2 2 0 AAA domain CMS1 PF14617.6 EHT99688.1 - 0.047 13.0 0.0 0.047 13.0 0.0 2.5 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit WSD PF15613.6 EHT99688.1 - 0.058 13.9 0.2 0.058 13.9 0.2 2.2 3 0 0 3 3 3 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif MTS PF05175.14 EHT99689.1 - 3.2e-11 43.1 0.0 4.7e-11 42.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EHT99689.1 - 9.5e-08 32.7 0.0 1.7e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EHT99689.1 - 1.1e-06 28.6 0.0 1.7e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 EHT99689.1 - 1e-05 25.3 0.0 1.3e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.13 EHT99689.1 - 2.1e-05 24.1 0.1 3.2e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_3 PF01596.17 EHT99689.1 - 3.1e-05 23.2 0.0 4.2e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.6 EHT99689.1 - 7.4e-05 22.6 0.0 0.00016 21.6 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_10 PF05971.12 EHT99689.1 - 0.00045 19.6 0.0 0.0006 19.2 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase PCMT PF01135.19 EHT99689.1 - 0.0055 16.5 0.0 0.0078 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 EHT99689.1 - 0.0059 16.5 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 EHT99689.1 - 0.0072 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 EHT99689.1 - 0.0076 16.2 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EHT99689.1 - 0.015 16.0 0.0 0.034 14.8 0.0 1.6 2 0 0 2 2 1 0 Methyltransferase domain PRMT5 PF05185.16 EHT99689.1 - 0.066 13.0 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Carb_kinase PF01256.17 EHT99689.1 - 0.11 12.0 0.1 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 Carbohydrate kinase FAD_binding_2 PF00890.24 EHT99690.1 - 2.4e-99 333.3 1.5 2.9e-99 333.0 1.5 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EHT99690.1 - 6.2e-15 55.3 0.1 1.5e-14 54.1 0.1 1.6 1 1 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 EHT99690.1 - 1.6e-09 37.4 0.2 2.1e-05 23.9 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EHT99690.1 - 8.7e-08 32.1 5.5 4.7e-06 26.4 5.3 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EHT99690.1 - 2e-05 24.0 0.5 0.064 12.5 0.2 2.9 1 1 1 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 EHT99690.1 - 0.0002 20.8 0.2 0.00034 20.0 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EHT99690.1 - 0.00063 19.9 1.3 0.0018 18.4 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EHT99690.1 - 0.003 16.7 0.1 0.0061 15.6 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 EHT99690.1 - 0.013 14.2 0.2 0.23 10.1 0.2 2.3 2 0 0 2 2 2 0 HI0933-like protein GMC_oxred_N PF00732.19 EHT99690.1 - 0.033 13.5 0.1 4.5 6.5 0.0 2.3 2 0 0 2 2 2 0 GMC oxidoreductase K_oxygenase PF13434.6 EHT99690.1 - 0.081 12.1 0.1 3 6.9 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) GARS_N PF02844.15 EHT99690.1 - 0.18 12.6 0.0 0.35 11.7 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain Sigma70_r4_2 PF08281.12 EHT99691.1 - 9.2e-19 66.9 0.1 2.1e-18 65.7 0.1 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 EHT99691.1 - 3.3e-17 62.0 0.2 6e-17 61.2 0.2 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 EHT99691.1 - 5.3e-10 38.7 0.0 1.1e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 EHT99691.1 - 1.4e-07 31.6 0.1 4.9e-07 29.8 0.1 1.8 1 1 0 1 1 1 1 ECF sigma factor HTH_23 PF13384.6 EHT99691.1 - 0.0022 17.7 0.0 0.0059 16.4 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_16 PF12645.7 EHT99691.1 - 0.074 13.1 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain RseA_N PF03872.13 EHT99692.1 - 2.2e-35 121.0 0.4 2.2e-35 121.0 0.4 1.8 2 0 0 2 2 2 1 Anti sigma-E protein RseA, N-terminal domain RseA_C PF03873.13 EHT99692.1 - 9.7e-24 83.4 0.6 9.7e-24 83.4 0.6 2.4 3 0 0 3 3 3 1 Anti sigma-E protein RseA, C-terminal domain RskA PF10099.9 EHT99692.1 - 0.002 18.5 0.6 0.0035 17.7 0.6 1.5 1 1 0 1 1 1 1 Anti-sigma-K factor rskA MucB_RseB PF03888.14 EHT99693.1 - 1.4e-60 203.8 0.0 3.1e-60 202.8 0.0 1.5 2 0 0 2 2 2 1 MucB/RseB N-terminal domain MucB_RseB_C PF17188.4 EHT99693.1 - 2.1e-26 92.0 0.0 3.5e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 MucB/RseB C-terminal domain LolA_like PF17131.4 EHT99693.1 - 0.00019 21.2 0.0 0.00034 20.4 0.0 1.3 1 0 0 1 1 1 1 Outer membrane lipoprotein-sorting protein MliC PF09864.9 EHT99693.1 - 0.13 12.3 0.4 3.8 7.5 0.0 2.8 3 0 0 3 3 3 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme UVR PF02151.19 EHT99693.1 - 0.18 11.6 0.5 0.37 10.6 0.5 1.4 1 0 0 1 1 1 0 UvrB/uvrC motif RseC_MucC PF04246.12 EHT99694.1 - 4.3e-35 120.5 0.0 4.9e-35 120.3 0.0 1.0 1 0 0 1 1 1 1 Positive regulator of sigma(E), RseC/MucC PCuAC PF04314.13 EHT99694.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Copper chaperone PCu(A)C GTP_EFTU PF00009.27 EHT99695.1 - 6.3e-52 175.9 0.0 1.2e-51 175.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 EHT99695.1 - 1.1e-49 167.0 1.7 1.8e-49 166.4 1.7 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 EHT99695.1 - 3.6e-20 71.8 0.0 7.7e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EHT99695.1 - 4.6e-11 43.0 0.3 1.1e-10 41.8 0.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EHT99695.1 - 2.6e-05 24.3 0.0 8.3e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 EHT99695.1 - 7.6e-05 22.4 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 Ras family EFG_II PF14492.6 EHT99695.1 - 0.00033 20.7 0.0 0.0011 19.0 0.0 1.9 1 1 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.10 EHT99695.1 - 0.033 13.6 0.0 0.076 12.4 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RF3_C PF16658.5 EHT99695.1 - 0.056 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Peptidase_S24 PF00717.23 EHT99696.1 - 5.1e-22 77.6 0.0 8.4e-22 76.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EHT99696.1 - 1.2e-09 38.0 0.0 3e-07 30.3 0.0 2.3 2 0 0 2 2 2 2 Signal peptidase, peptidase S26 Ribonucleas_3_3 PF14622.6 EHT99697.1 - 1.3e-33 115.8 0.0 1.9e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EHT99697.1 - 5e-20 72.1 0.0 9.8e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 EHT99697.1 - 2.3e-14 53.8 0.0 3.7e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 EHT99697.1 - 1.7e-05 25.0 0.1 3.4e-05 24.0 0.1 1.5 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 MMR_HSR1 PF01926.23 EHT99698.1 - 1.1e-23 83.5 0.0 2.5e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase KH_2 PF07650.17 EHT99698.1 - 9.3e-21 73.5 1.1 4.3e-20 71.3 1.0 2.1 2 0 0 2 2 2 1 KH domain FeoB_N PF02421.18 EHT99698.1 - 2e-14 53.4 0.1 3.2e-14 52.8 0.1 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EHT99698.1 - 1.3e-08 34.9 0.2 0.00026 21.0 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EHT99698.1 - 1.4e-08 34.5 0.2 1.9e-06 27.6 0.2 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EHT99698.1 - 6e-07 29.7 0.1 0.00015 21.9 0.1 2.4 1 1 1 2 2 2 1 Dynamin family AIG1 PF04548.16 EHT99698.1 - 3.5e-06 26.5 0.0 6.2e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Ras PF00071.22 EHT99698.1 - 2.4e-05 24.0 0.0 0.0019 17.8 0.0 3.0 2 1 0 2 2 2 1 Ras family AAA_22 PF13401.6 EHT99698.1 - 9e-05 22.8 0.0 0.00018 21.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 EHT99698.1 - 0.00033 20.4 0.1 0.0048 16.6 0.1 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EHT99698.1 - 0.0023 17.4 0.1 0.007 15.8 0.1 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EHT99698.1 - 0.0047 17.1 0.4 0.034 14.3 0.1 2.5 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1_Xtn PF16897.5 EHT99698.1 - 0.016 15.3 0.1 0.037 14.0 0.1 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain NB-ARC PF00931.22 EHT99698.1 - 0.02 14.1 0.0 0.11 11.6 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain ABC_tran PF00005.27 EHT99698.1 - 0.037 14.5 0.0 0.08 13.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter cobW PF02492.19 EHT99698.1 - 0.063 12.9 0.2 9.8 5.7 0.0 2.3 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 EHT99698.1 - 0.065 13.6 0.2 0.31 11.4 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.6 EHT99698.1 - 0.13 12.3 0.1 0.31 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain RecO_C PF02565.15 EHT99699.1 - 3.9e-23 82.0 1.0 1.2e-22 80.4 1.0 1.7 1 1 0 1 1 1 1 Recombination protein O C terminal RecO_N PF11967.8 EHT99699.1 - 3.6e-22 78.1 0.0 7.1e-22 77.2 0.0 1.5 1 0 0 1 1 1 1 Recombination protein O N terminal PdxJ PF03740.13 EHT99700.1 - 3.1e-106 353.8 1.0 3.5e-106 353.6 1.0 1.0 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthesis protein PdxJ AP_endonuc_2 PF01261.24 EHT99700.1 - 0.0013 18.2 0.2 0.011 15.2 0.1 2.2 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel PEP_mutase PF13714.6 EHT99700.1 - 0.013 14.9 0.5 3.2 7.2 0.0 2.2 2 0 0 2 2 2 0 Phosphoenolpyruvate phosphomutase ACPS PF01648.20 EHT99701.1 - 3.2e-24 85.3 0.0 3.5e-24 85.1 0.0 1.0 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Tecti-min-caps PF09300.10 EHT99701.1 - 0.003 17.6 0.1 0.0056 16.7 0.1 1.4 1 0 0 1 1 1 1 Tectiviridae, minor capsid AP_endonuc_2 PF01261.24 EHT99701.1 - 0.06 12.8 0.1 0.13 11.7 0.0 1.5 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel Fer4_20 PF14691.6 EHT99702.1 - 0.0052 16.5 0.4 0.0059 16.4 0.4 1.1 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_2 PF12797.7 EHT99702.1 - 0.01 15.9 2.0 0.017 15.2 2.0 1.4 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_10 PF13237.6 EHT99702.1 - 0.01 15.9 1.2 0.016 15.3 1.2 1.3 1 1 0 1 1 1 0 4Fe-4S dicluster domain Phage_integrase PF00589.22 EHT99703.1 - 5e-05 23.2 0.0 0.00013 21.8 0.0 1.6 2 0 0 2 2 2 1 Phage integrase family SNF2_N PF00176.23 EHT99704.1 - 1.1e-12 47.4 0.0 1.5e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EHT99704.1 - 0.015 15.6 0.0 0.06 13.7 0.0 2.0 2 0 0 2 2 2 0 Helicase conserved C-terminal domain VRR_NUC PF08774.11 EHT99705.1 - 5.7e-05 23.1 0.0 9.2e-05 22.5 0.0 1.3 1 1 0 1 1 1 1 VRR-NUC domain PerC PF06069.11 EHT99706.1 - 0.00013 22.2 1.5 0.00016 21.9 1.5 1.1 1 0 0 1 1 1 1 PerC transcriptional activator DNA_pol_A PF00476.20 EHT99707.1 - 2e-12 46.9 0.0 2.8e-08 33.2 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 EHT99707.1 - 0.00037 20.3 0.1 0.015 15.0 0.0 2.3 2 0 0 2 2 2 2 3'-5' exonuclease DUF2303 PF10065.9 EHT99708.1 - 3.4e-60 203.5 0.0 4.3e-60 203.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2303) DDE_Tnp_IS66 PF03050.14 EHT99710.1 - 9.3e-98 327.2 0.0 1.1e-97 327.0 0.0 1.0 1 0 0 1 1 1 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT99710.1 - 2.3e-16 59.7 0.1 7.7e-16 58.0 0.1 2.0 1 0 0 1 1 1 1 IS66 C-terminal element Form_Nir_trans PF01226.17 EHT99711.1 - 7.7e-77 257.8 32.1 8.7e-77 257.6 32.1 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter DUF1323 PF07037.11 EHT99712.1 - 9.8e-41 139.0 0.1 1.2e-40 138.7 0.1 1.1 1 0 0 1 1 1 1 Putative transcription regulator (DUF1323) HTH_29 PF13551.6 EHT99712.1 - 0.00051 20.0 0.0 0.00097 19.1 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 EHT99712.1 - 0.0036 17.1 0.0 0.0074 16.1 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain Terminase_5 PF06056.12 EHT99712.1 - 0.008 16.0 0.1 0.013 15.4 0.1 1.3 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) HTH_17 PF12728.7 EHT99712.1 - 0.01 16.0 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_28 PF13518.6 EHT99712.1 - 0.016 15.3 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_Mu_1 PF02316.16 EHT99712.1 - 0.022 14.9 1.1 0.21 11.8 1.1 2.0 1 1 0 1 1 1 0 Mu DNA-binding domain HTH_3 PF01381.22 EHT99712.1 - 0.036 14.1 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix tRNA-synt_1c PF00749.21 EHT99713.1 - 8.7e-74 248.2 0.0 1.1e-73 247.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain HTH_15 PF12324.8 EHT99713.1 - 0.054 13.5 0.7 7.1 6.7 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase DDE_3 PF13358.6 EHT99714.1 - 3.8e-16 59.1 0.0 5.1e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.6 EHT99714.1 - 2.6e-07 30.2 2.4 1.8e-06 27.5 0.3 2.3 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.6 EHT99714.1 - 0.0038 17.8 0.1 0.012 16.2 0.1 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_1 PF01527.20 EHT99715.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT99715.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT99715.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT99715.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHT99716.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHT99717.1 - 4.2e-98 328.3 3.2 3.2e-97 325.4 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT99717.1 - 3.1e-16 59.3 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT99717.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT99717.1 - 9.1e-12 45.6 8.5 1.9e-11 44.6 8.5 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FUSC PF04632.12 EHT99717.1 - 0.046 12.3 7.1 0.072 11.6 7.1 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Phage_HK97_TLTM PF06120.11 EHT99717.1 - 0.046 12.9 1.3 0.09 12.0 1.3 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Exonuc_VII_L PF02601.15 EHT99717.1 - 0.05 13.2 1.7 0.072 12.6 0.5 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit LXG PF04740.12 EHT99717.1 - 0.1 12.3 1.6 0.81 9.4 0.3 2.2 1 1 1 2 2 2 0 LXG domain of WXG superfamily Csm1_N PF18504.1 EHT99717.1 - 0.13 12.6 3.2 0.93 9.9 0.2 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain FAM184 PF15665.5 EHT99717.1 - 0.15 11.8 4.7 0.24 11.2 4.7 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B DHR10 PF18595.1 EHT99717.1 - 0.18 11.9 10.2 0.31 11.1 10.2 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain HalX PF08663.10 EHT99717.1 - 0.22 11.8 2.3 0.6 10.5 2.3 1.7 1 0 0 1 1 1 0 HalX domain ALIX_LYPXL_bnd PF13949.6 EHT99717.1 - 0.23 10.7 4.0 0.39 9.9 4.0 1.3 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV TSNAXIP1_N PF15739.5 EHT99717.1 - 0.26 11.7 2.9 0.56 10.6 2.9 1.5 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus ERM PF00769.19 EHT99717.1 - 0.29 10.9 10.4 0.48 10.2 10.4 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HHH_8 PF14716.6 EHT99717.1 - 0.36 11.2 4.1 0.92 9.9 2.6 2.4 2 1 0 2 2 2 0 Helix-hairpin-helix domain Zn-ribbon_8 PF09723.10 EHT99717.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain CREPT PF16566.5 EHT99717.1 - 0.48 10.6 7.6 0.22 11.7 4.5 1.8 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour HAUS-augmin3 PF14932.6 EHT99717.1 - 1.2 8.6 6.9 2.9 7.4 6.9 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 ABC_tran_CTD PF16326.5 EHT99717.1 - 2 8.7 6.7 0.3 11.4 1.2 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain SlyX PF04102.12 EHT99717.1 - 7.3 7.3 8.3 15 6.3 1.9 3.0 1 1 1 2 2 2 0 SlyX Gp138_N PF18352.1 EHT99718.1 - 1.8e-32 111.3 0.0 6.5e-32 109.5 0.0 2.0 1 1 0 1 1 1 1 Phage protein Gp138 N-terminal domain Phage_integrase PF00589.22 EHT99719.1 - 1.9e-21 76.6 0.0 3.1e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Arm-DNA-bind_3 PF13356.6 EHT99719.1 - 3.4e-18 65.8 0.3 9.9e-18 64.3 0.3 1.8 1 0 0 1 1 1 1 Arm DNA-binding domain Phage_portal PF04860.12 EHT99720.1 - 4.9e-15 55.5 0.0 6.7e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Phage portal protein Ogr_Delta PF04606.12 EHT99724.1 - 2e-14 53.3 2.2 3e-14 52.7 2.2 1.3 1 0 0 1 1 1 1 Ogr/Delta-like zinc finger Lar_restr_allev PF14354.6 EHT99724.1 - 0.06 13.7 0.2 0.08 13.3 0.2 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.7 EHT99724.1 - 0.069 13.1 2.3 0.11 12.5 2.3 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Psu PF07455.11 EHT99725.1 - 0.00064 19.4 3.9 0.026 14.1 0.0 2.3 1 1 1 2 2 2 2 Phage polarity suppression protein (Psu) APG17 PF04108.12 EHT99725.1 - 0.37 9.9 5.3 0.63 9.1 3.6 1.9 2 0 0 2 2 2 0 Autophagy protein Apg17 DUF927 PF06048.11 EHT99727.1 - 1.7e-98 329.8 0.3 2.5e-98 329.2 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF927) Prim_Zn_Ribbon PF08273.12 EHT99727.1 - 1.5e-16 60.4 9.8 1.5e-16 60.4 9.8 2.6 3 0 0 3 3 3 1 Zinc-binding domain of primase-helicase Toprim_3 PF13362.6 EHT99727.1 - 8.1e-14 51.8 0.0 2.8e-13 50.0 0.0 2.0 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 EHT99727.1 - 0.0023 18.4 0.0 0.0071 16.8 0.0 1.9 1 0 0 1 1 1 1 Toprim domain Zn_Tnp_IS1595 PF12760.7 EHT99727.1 - 0.0024 17.8 1.0 0.0068 16.4 1.0 1.7 1 0 0 1 1 1 1 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.12 EHT99727.1 - 0.0049 16.4 1.7 0.01 15.4 1.7 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding zf-RRN7 PF11781.8 EHT99727.1 - 0.01 15.5 3.6 0.035 13.8 3.6 2.0 1 1 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Toprim_2 PF13155.6 EHT99727.1 - 0.018 15.4 0.0 0.046 14.2 0.0 1.7 1 0 0 1 1 1 0 Toprim-like DUF5375 PF17345.2 EHT99728.1 - 1.2e-14 54.1 0.2 1.5e-14 53.8 0.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5375) DUF4222 PF13973.6 EHT99730.1 - 0.0022 17.5 0.0 0.024 14.2 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4222) HTH_Tnp_Tc3_2 PF01498.18 EHT99732.1 - 0.092 13.0 0.0 0.095 13.0 0.0 1.1 1 0 0 1 1 1 0 Transposase DDE_3 PF13358.6 EHT99733.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHT99733.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHT99733.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHT99733.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHT99733.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHT99733.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHT99733.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHT99733.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 GDPD PF03009.17 EHT99734.1 - 3.4e-25 89.3 0.0 1.8e-23 83.6 0.0 2.0 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family PI-PLC-X PF00388.19 EHT99734.1 - 0.2 11.2 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain ABC_tran PF00005.27 EHT99735.1 - 2.9e-38 131.5 0.0 4.3e-38 130.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 EHT99735.1 - 7.4e-09 35.7 0.0 1.6e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 TOBE domain OB_MalK PF17912.1 EHT99735.1 - 1.1e-07 32.5 0.0 3.2e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 MalK OB fold domain AAA_21 PF13304.6 EHT99735.1 - 3e-05 24.0 1.7 0.0077 16.1 0.2 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EHT99735.1 - 0.00011 21.7 0.3 0.029 13.8 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain CysA_C_terminal PF17850.1 EHT99735.1 - 0.00043 20.8 0.1 0.00096 19.7 0.1 1.6 1 0 0 1 1 1 1 CysA C-terminal regulatory domain AAA_29 PF13555.6 EHT99735.1 - 0.0017 18.1 0.0 0.0038 16.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Rad17 PF03215.15 EHT99735.1 - 0.0029 17.5 0.0 0.0048 16.8 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_25 PF13481.6 EHT99735.1 - 0.01 15.4 0.0 0.12 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EHT99735.1 - 0.062 13.6 0.8 0.23 11.8 0.9 2.0 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EHT99735.1 - 0.063 13.8 0.0 0.22 12.1 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 EHT99735.1 - 0.09 13.2 0.3 0.18 12.2 0.3 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 EHT99735.1 - 0.09 13.3 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EHT99735.1 - 0.093 13.0 0.0 0.35 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EHT99735.1 - 0.099 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase BPD_transp_1 PF00528.22 EHT99736.1 - 1.9e-07 31.0 38.9 0.00017 21.4 38.9 2.9 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 EHT99737.1 - 1.8e-12 47.4 13.0 1.8e-12 47.4 13.0 2.1 1 1 0 2 2 2 2 Binding-protein-dependent transport system inner membrane component SBP_bac_1 PF01547.25 EHT99738.1 - 2.2e-27 96.8 17.2 3.3e-27 96.3 17.2 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein ROK PF00480.20 EHT99739.1 - 5.1e-24 85.3 0.0 5.1e-22 78.7 0.0 2.1 1 1 1 2 2 2 2 ROK family MarR_2 PF12802.7 EHT99739.1 - 5.8e-08 32.5 0.5 1.9e-07 30.9 0.2 2.0 2 0 0 2 2 2 1 MarR family HTH_24 PF13412.6 EHT99739.1 - 4.2e-05 23.0 0.0 7.5e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 EHT99739.1 - 0.00047 20.1 0.1 0.002 18.1 0.1 2.1 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain MarR PF01047.22 EHT99739.1 - 0.00081 19.3 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 EHT99739.1 - 0.0032 17.5 0.1 0.0062 16.6 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_27 PF13463.6 EHT99739.1 - 0.015 15.7 0.0 0.17 12.4 0.0 2.5 3 0 0 3 3 3 0 Winged helix DNA-binding domain HTH_IclR PF09339.10 EHT99739.1 - 0.02 14.7 0.0 0.067 13.0 0.0 1.9 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_34 PF13601.6 EHT99739.1 - 0.11 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain RES PF08808.11 EHT99740.1 - 3e-10 40.2 0.2 3.8e-10 39.9 0.2 1.1 1 0 0 1 1 1 1 RES domain STN PF07660.14 EHT99741.1 - 0.0033 17.2 0.0 0.0048 16.7 0.0 1.3 1 0 0 1 1 1 1 Secretin and TonB N terminus short domain DUF2767 PF10965.8 EHT99742.1 - 0.00088 19.2 0.2 0.0014 18.6 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2767) MFS_1 PF07690.16 EHT99743.1 - 5.2e-30 104.6 47.6 3.6e-17 62.3 21.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EHT99743.1 - 0.0003 19.8 3.6 0.0003 19.8 3.6 2.9 1 1 0 2 2 2 2 Sugar (and other) transporter DUF443 PF04276.12 EHT99743.1 - 9.9 5.9 8.2 1.1 9.1 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) SGL PF08450.12 EHT99744.1 - 1.4e-74 250.8 0.0 1.6e-74 250.6 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region LPAM_1 PF08139.12 EHT99746.1 - 0.51 10.9 2.9 0.74 10.4 2.9 1.3 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site DUF4131 PF13567.6 EHT99748.1 - 0.021 14.5 2.4 0.026 14.2 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) PalH PF08733.10 EHT99748.1 - 0.03 13.3 3.2 0.036 13.1 3.2 1.1 1 0 0 1 1 1 0 PalH/RIM21 DUF2070 PF09843.9 EHT99748.1 - 0.031 12.6 0.8 0.036 12.4 0.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ABC2_membrane_2 PF12679.7 EHT99748.1 - 0.045 13.0 0.3 0.047 13.0 0.3 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein YajC PF02699.15 EHT99748.1 - 0.22 11.4 0.2 0.22 11.4 0.2 2.2 2 0 0 2 2 2 0 Preprotein translocase subunit DUF3043 PF11241.8 EHT99748.1 - 0.42 10.6 3.3 0.6 10.1 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Usp PF00582.26 EHT99749.1 - 2e-27 96.4 1.2 2.2e-27 96.3 1.2 1.0 1 0 0 1 1 1 1 Universal stress protein family IclR PF01614.18 EHT99750.1 - 3.2e-19 69.0 0.1 7.2e-19 67.9 0.0 1.6 2 0 0 2 2 2 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 EHT99750.1 - 9.7e-14 50.9 0.1 2.4e-13 49.7 0.1 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 EHT99750.1 - 2.8e-08 33.5 0.3 8.5e-08 32.0 0.3 1.8 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 EHT99750.1 - 1.6e-06 27.5 0.0 3.3e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Rrf2 PF02082.20 EHT99750.1 - 5.9e-06 26.6 0.2 1.3e-05 25.5 0.2 1.6 1 0 0 1 1 1 1 Transcriptional regulator HTH_20 PF12840.7 EHT99750.1 - 6.3e-05 22.9 0.2 0.00019 21.4 0.1 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain TrmB PF01978.19 EHT99750.1 - 0.0011 18.8 0.0 0.0023 17.8 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_23 PF13384.6 EHT99750.1 - 0.0024 17.6 0.0 0.0077 16.0 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_5 PF01022.20 EHT99750.1 - 0.0028 17.5 0.3 0.013 15.4 0.0 2.2 3 0 0 3 3 2 1 Bacterial regulatory protein, arsR family HTH_AsnC-type PF13404.6 EHT99750.1 - 0.004 17.0 0.2 0.012 15.4 0.0 1.9 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain MarR PF01047.22 EHT99750.1 - 0.0046 16.9 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_28 PF13518.6 EHT99750.1 - 0.025 14.7 0.0 0.052 13.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.12 EHT99750.1 - 0.037 14.0 0.0 0.37 10.8 0.0 2.3 2 0 0 2 2 2 0 HTH domain HTH_Mga PF08280.11 EHT99750.1 - 0.038 14.0 0.0 0.17 11.9 0.0 1.9 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain Sigma70_r4 PF04545.16 EHT99750.1 - 0.053 13.0 0.0 0.21 11.2 0.0 2.0 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Crp_2 PF13545.6 EHT99750.1 - 0.054 13.5 0.1 0.28 11.2 0.0 2.1 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_47 PF16221.5 EHT99750.1 - 0.065 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 winged helix-turn-helix HTH_38 PF13936.6 EHT99750.1 - 0.1 12.4 0.0 0.4 10.5 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_3 PF01381.22 EHT99750.1 - 0.11 12.5 0.0 0.69 10.0 0.0 2.3 1 1 1 2 2 2 0 Helix-turn-helix MFS_1 PF07690.16 EHT99751.1 - 4.4e-26 91.6 45.8 6.7e-26 91.0 45.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily HlyD_D23 PF16576.5 EHT99752.1 - 1.2e-19 70.4 11.2 5.6e-18 65.0 11.2 2.5 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 EHT99752.1 - 4e-17 62.8 8.1 2.2e-14 54.0 1.3 2.8 2 1 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 EHT99752.1 - 1.4e-16 60.0 8.5 1.3e-15 56.9 0.5 3.7 3 1 0 3 3 3 2 Biotin-lipoyl like HlyD PF00529.20 EHT99752.1 - 2.4e-10 40.1 15.3 3.5e-10 39.6 15.3 1.4 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl PF00364.22 EHT99752.1 - 0.00041 20.1 0.0 0.03 14.1 0.0 2.4 2 0 0 2 2 2 1 Biotin-requiring enzyme Neur_chan_memb PF02932.16 EHT99752.1 - 0.03 14.4 0.5 0.044 13.8 0.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_M23 PF01551.22 EHT99752.1 - 0.058 13.6 0.0 2.4 8.4 0.0 2.5 2 0 0 2 2 2 0 Peptidase family M23 SKA1 PF07160.12 EHT99752.1 - 0.07 13.0 3.3 0.1 12.4 3.3 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 SIT PF15330.6 EHT99752.1 - 0.075 13.5 0.3 0.075 13.5 0.3 2.4 2 1 1 3 3 3 0 SHP2-interacting transmembrane adaptor protein, SIT DUF16 PF01519.16 EHT99752.1 - 1 9.9 4.0 8.1 7.0 1.8 2.6 1 1 0 2 2 2 0 Protein of unknown function DUF16 CCDC53 PF10152.9 EHT99752.1 - 2.2 8.7 6.8 4 7.8 6.8 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Aminotran_1_2 PF00155.21 EHT99754.1 - 4.8e-59 200.4 0.0 5.4e-59 200.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 EHT99754.1 - 0.0055 15.6 0.0 0.18 10.6 0.0 2.2 2 0 0 2 2 2 2 Allinase Beta_elim_lyase PF01212.21 EHT99754.1 - 0.06 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EHT99754.1 - 0.14 10.7 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Acetyltransf_3 PF13302.7 EHT99755.1 - 1.6e-23 83.9 0.0 1.8e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EHT99755.1 - 2.1e-05 24.7 0.0 2.6e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 EHT99755.1 - 0.0028 17.8 0.0 0.003 17.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EHT99755.1 - 0.0093 15.9 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein DUF1336 PF07059.12 EHT99755.1 - 0.027 14.5 0.0 0.036 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1336) 5TM-5TMR_LYT PF07694.12 EHT99756.1 - 9.8e-43 145.6 15.3 1.8e-42 144.7 15.3 1.5 1 0 0 1 1 1 1 5TMR of 5TMR-LYT His_kinase PF06580.13 EHT99756.1 - 4.9e-25 87.7 0.4 1.1e-24 86.5 0.4 1.6 1 0 0 1 1 1 1 Histidine kinase HATPase_c PF02518.26 EHT99756.1 - 8.2e-08 32.7 0.1 1.8e-07 31.6 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_2 PF13185.6 EHT99756.1 - 1.9e-07 31.5 0.0 7.3e-06 26.3 0.0 2.5 2 0 0 2 2 2 1 GAF domain ECF-ribofla_trS PF07155.12 EHT99756.1 - 2.5e-05 24.4 13.3 4.6e-05 23.5 13.3 1.4 1 0 0 1 1 1 1 ECF-type riboflavin transporter, S component GAF_3 PF13492.6 EHT99756.1 - 0.00013 22.3 0.0 0.014 15.7 0.0 2.4 2 0 0 2 2 2 1 GAF domain MFS_1 PF07690.16 EHT99756.1 - 0.00024 20.1 12.1 0.00037 19.5 12.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ECF_trnsprt PF12822.7 EHT99756.1 - 0.00025 21.2 12.3 0.00059 20.0 12.3 1.7 1 0 0 1 1 1 1 ECF transporter, substrate-specific component GAF PF01590.26 EHT99756.1 - 0.00086 19.9 0.3 0.0032 18.1 0.0 2.1 3 0 0 3 3 2 1 GAF domain SpoVT_C PF15714.5 EHT99756.1 - 0.0016 18.5 2.0 0.012 15.6 0.1 2.3 2 0 0 2 2 2 1 Stage V sporulation protein T C-terminal, transcription factor HATPase_c_2 PF13581.6 EHT99756.1 - 0.09 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Bac_export_3 PF01313.19 EHT99756.1 - 4.9 7.2 12.0 7.8 6.5 2.9 3.6 3 0 0 3 3 3 0 Bacterial export proteins, family 3 LytTR PF04397.15 EHT99757.1 - 2.3e-31 107.9 0.5 4.8e-31 106.9 0.5 1.6 1 0 0 1 1 1 1 LytTr DNA-binding domain Response_reg PF00072.24 EHT99757.1 - 2.1e-23 82.6 0.1 3.5e-23 81.9 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Glucokinase PF02685.16 EHT99758.1 - 1.1e-125 418.9 0.0 1.2e-125 418.7 0.0 1.0 1 0 0 1 1 1 1 Glucokinase TPP_enzyme_N PF02776.18 EHT99760.1 - 9.4e-30 103.5 0.7 9.4e-30 103.5 0.7 1.9 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EHT99760.1 - 3.5e-17 62.6 1.8 2.8e-16 59.7 0.0 2.6 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EHT99760.1 - 3.8e-16 59.1 0.0 1.6e-15 57.1 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain XFP_N PF09364.10 EHT99760.1 - 0.025 13.4 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 XFP N-terminal domain Aldo_ket_red PF00248.21 EHT99761.1 - 2e-68 230.8 0.0 2.2e-68 230.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2502 PF10697.9 EHT99762.1 - 1.4e-12 47.8 11.8 4.3e-12 46.2 11.8 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2502) Methyltransf_3 PF01596.17 EHT99764.1 - 2.2e-26 92.3 0.0 2.8e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EHT99764.1 - 7.7e-17 62.2 0.0 1.4e-16 61.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EHT99764.1 - 9e-12 45.2 0.0 1.1e-11 44.9 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EHT99764.1 - 5.5e-08 32.7 0.0 7.2e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EHT99764.1 - 1.7e-06 28.7 0.0 3e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EHT99764.1 - 6.5e-05 23.5 0.0 9.9e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EHT99764.1 - 0.0012 18.5 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.7 EHT99764.1 - 0.0021 18.0 0.0 0.0026 17.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 EHT99764.1 - 0.0042 16.8 0.0 0.0046 16.7 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltr_RsmB-F PF01189.17 EHT99764.1 - 0.036 13.7 0.0 0.05 13.2 0.0 1.1 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_12 PF08242.12 EHT99764.1 - 0.12 13.2 0.0 0.18 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Cys_Met_Meta_PP PF01053.20 EHT99764.1 - 0.16 10.5 0.0 0.18 10.3 0.0 1.0 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme PrmA PF06325.13 EHT99764.1 - 0.18 11.2 0.0 0.22 10.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 EHT99764.1 - 0.18 11.6 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain CmcI PF04989.12 EHT99764.1 - 0.18 11.4 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase Nramp PF01566.18 EHT99765.1 - 1e-123 412.9 30.1 1.3e-123 412.6 30.1 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Nucleos_tra2_C PF07662.13 EHT99766.1 - 2.1e-61 207.4 10.7 2.1e-61 207.4 10.7 2.2 2 1 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 EHT99766.1 - 8.2e-19 68.0 6.2 8.2e-19 68.0 6.2 4.1 3 1 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 EHT99766.1 - 4.2e-06 27.0 7.5 4.2e-06 27.0 7.5 4.4 2 1 1 4 4 4 1 Nucleoside recognition NTP_transf_2 PF01909.23 EHT99767.1 - 2.2e-05 24.6 0.0 9.1e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyltransferase domain Polbeta PF18765.1 EHT99767.1 - 0.0016 18.5 0.0 0.0036 17.4 0.0 1.5 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase DUF3352 PF11832.8 EHT99767.1 - 0.043 12.5 0.0 0.09 11.4 0.0 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3352) DDE_3 PF13358.6 EHT99768.1 - 6.1e-23 81.2 0.0 9.9e-23 80.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 EHT99768.1 - 1.1e-10 41.0 1.0 3.6e-09 36.2 0.1 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 EHT99768.1 - 4.2e-09 36.9 1.1 2.8e-08 34.3 0.3 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 EHT99768.1 - 3.9e-07 30.0 1.2 1.1e-06 28.6 0.3 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_33 PF13592.6 EHT99768.1 - 3.1e-06 26.7 5.1 4.4e-06 26.2 0.3 2.9 3 0 0 3 3 3 1 Winged helix-turn helix HTH_28 PF13518.6 EHT99768.1 - 1.4e-05 25.1 0.3 0.0002 21.4 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHT99768.1 - 0.031 14.8 0.2 0.061 13.8 0.2 1.4 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 HTH_38 PF13936.6 EHT99768.1 - 0.054 13.3 0.6 0.16 11.8 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain QRPTase_C PF01729.19 EHT99769.1 - 1.3e-58 197.5 0.2 1.7e-58 197.2 0.2 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 EHT99769.1 - 8.3e-26 89.9 0.0 3.9e-24 84.5 0.0 2.8 2 1 1 3 3 3 1 Quinolinate phosphoribosyl transferase, N-terminal domain Biotin_lipoyl_2 PF13533.6 EHT99769.1 - 0.021 14.7 0.0 0.062 13.1 0.0 1.7 1 0 0 1 1 1 0 Biotin-lipoyl like IMPDH PF00478.25 EHT99769.1 - 0.1 11.6 0.2 0.15 11.1 0.2 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain DUF816 PF05674.12 EHT99769.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF816) Amidase_2 PF01510.25 EHT99770.1 - 4e-29 101.6 0.0 4.4e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase DDE_Tnp_IS66 PF03050.14 EHT99771.1 - 7.4e-97 324.2 0.0 8.5e-97 324.0 0.0 1.0 1 0 0 1 1 1 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT99771.1 - 2.5e-16 59.6 0.1 7.7e-16 58.0 0.1 1.9 1 0 0 1 1 1 1 IS66 C-terminal element Peptidase_S9 PF00326.21 EHT99772.1 - 1.3e-36 126.0 0.1 2.3e-36 125.3 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 EHT99772.1 - 1.8e-35 122.5 0.0 2.2e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain AXE1 PF05448.12 EHT99772.1 - 0.095 11.3 0.5 0.46 9.1 0.0 2.1 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 EHT99773.1 - 2.3e-08 33.8 0.0 2.3e-08 33.8 0.0 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase family RNase_T PF00929.24 EHT99774.1 - 1.2e-15 58.5 0.0 1.5e-14 54.9 0.0 2.0 1 1 0 1 1 1 1 Exonuclease QSregVF_b PF12843.7 EHT99774.1 - 0.033 14.1 0.0 0.068 13.1 0.0 1.5 1 0 0 1 1 1 0 Putative quorum-sensing-regulated virulence factor DNA_pol3_theta PF06440.11 EHT99775.1 - 1.9e-38 129.9 0.4 2.1e-38 129.8 0.4 1.0 1 0 0 1 1 1 1 DNA polymerase III, theta subunit DUF3283 PF11686.8 EHT99775.1 - 3e-05 23.8 1.4 0.0002 21.1 0.2 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF3283) GlgS PF08971.11 EHT99775.1 - 0.00059 19.8 0.2 0.0011 18.9 0.2 1.5 1 1 0 1 1 1 1 Glycogen synthesis protein CopC PF04234.12 EHT99776.1 - 1.6e-25 90.0 0.9 1.9e-25 89.7 0.9 1.1 1 0 0 1 1 1 1 CopC domain Big_5 PF13205.6 EHT99776.1 - 2.1e-05 25.2 0.5 3.3e-05 24.5 0.5 1.4 1 1 0 1 1 1 1 Bacterial Ig-like domain Wzt_C PF14524.6 EHT99776.1 - 0.046 13.8 0.0 0.071 13.1 0.0 1.2 1 0 0 1 1 1 0 Wzt C-terminal domain Big_8 PF17961.1 EHT99776.1 - 0.052 13.7 0.1 0.36 11.0 0.0 2.3 1 1 2 3 3 3 0 Bacterial Ig domain FlgD_ig PF13860.6 EHT99776.1 - 0.085 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 FlgD Ig-like domain CopD PF05425.13 EHT99777.1 - 1.9e-20 73.2 10.1 1.9e-20 73.2 10.1 3.1 3 1 0 3 3 3 1 Copper resistance protein D DUF2511 PF10709.9 EHT99778.1 - 2.1e-38 130.5 0.0 2.6e-38 130.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2511) MEKHLA PF08670.11 EHT99779.1 - 8.2e-31 106.8 0.0 9.7e-31 106.6 0.0 1.0 1 0 0 1 1 1 1 MEKHLA domain PAS_8 PF13188.7 EHT99779.1 - 0.01 15.9 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 0 PAS domain MCPsignal PF00015.21 EHT99780.1 - 2.5e-49 167.4 28.2 2.3e-48 164.3 17.3 3.0 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.7 EHT99780.1 - 2.4e-15 56.6 3.8 2.4e-15 56.6 3.8 3.3 4 1 0 4 4 4 1 Four helix bundle sensory module for signal transduction COG2 PF06148.11 EHT99780.1 - 0.039 14.0 0.5 0.039 14.0 0.5 3.5 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Yip1 PF04893.17 EHT99780.1 - 0.049 13.3 0.3 0.3 10.8 0.1 2.1 2 0 0 2 2 2 0 Yip1 domain MapZ_EC1 PF18041.1 EHT99780.1 - 0.073 13.3 0.1 0.073 13.3 0.1 2.4 2 0 0 2 2 2 0 MapZ extracellular domain 1 Acyl_transf_3 PF01757.22 EHT99782.1 - 1.1e-24 87.1 24.5 1.5e-24 86.7 24.5 1.1 1 0 0 1 1 1 1 Acyltransferase family XPG_N PF00752.17 EHT99782.1 - 0.11 13.0 0.0 0.35 11.4 0.0 1.9 2 0 0 2 2 2 0 XPG N-terminal domain Multi_Drug_Res PF00893.19 EHT99783.1 - 3.8e-26 91.6 4.4 5e-26 91.2 4.4 1.1 1 0 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 EHT99783.1 - 0.012 15.8 9.0 0.016 15.4 9.0 1.2 1 1 0 1 1 1 0 EamA-like transporter family Multi_Drug_Res PF00893.19 EHT99784.1 - 5.9e-24 84.6 8.0 5.9e-24 84.6 8.0 1.3 1 1 0 1 1 1 1 Small Multidrug Resistance protein UPF0060 PF02694.15 EHT99784.1 - 0.00051 20.2 5.7 0.00056 20.1 5.7 1.0 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family EamA PF00892.20 EHT99784.1 - 0.0054 16.9 10.9 0.0061 16.7 10.9 1.1 1 0 0 1 1 1 1 EamA-like transporter family Wzy_C PF04932.15 EHT99784.1 - 1.8 8.2 6.7 2.5 7.7 5.9 1.7 1 1 0 1 1 1 0 O-Antigen ligase DUF202 PF02656.15 EHT99784.1 - 5.7 7.5 7.5 96 3.5 7.5 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF202) GMC_oxred_N PF00732.19 EHT99785.1 - 4.5e-102 341.4 0.0 1.5e-101 339.7 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EHT99785.1 - 3.8e-41 141.0 0.0 5.6e-41 140.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EHT99785.1 - 0.00044 19.5 0.1 0.42 9.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EHT99785.1 - 0.0014 18.3 0.1 0.4 10.2 0.1 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EHT99785.1 - 0.0055 15.8 0.0 0.0082 15.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EHT99785.1 - 0.011 15.1 0.0 0.061 12.5 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EHT99785.1 - 0.012 15.8 0.1 0.035 14.3 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EHT99785.1 - 0.17 11.1 0.1 0.34 10.1 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Aldedh PF00171.22 EHT99786.1 - 1.5e-177 590.8 0.1 1.7e-177 590.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TetR_C_6 PF13977.6 EHT99787.1 - 6.2e-32 110.2 5.5 6.2e-32 110.2 5.5 2.1 2 1 1 3 3 3 1 BetI-type transcriptional repressor, C-terminal TetR_N PF00440.23 EHT99787.1 - 2.6e-13 49.5 0.0 7.2e-13 48.1 0.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family LacI PF00356.21 EHT99787.1 - 0.0048 16.7 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family TetR_C_31 PF17940.1 EHT99787.1 - 0.0072 16.5 11.5 0.0074 16.5 4.5 2.4 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_28 PF17937.1 EHT99787.1 - 0.0078 16.6 10.9 0.011 16.1 3.0 3.5 3 1 0 3 3 3 1 Tetracyclin repressor-like, C-terminal domain TetR_C_15 PF17918.1 EHT99787.1 - 0.0087 16.8 1.7 0.0087 16.8 1.7 2.3 2 1 1 3 3 3 1 Tetracyclin repressor-like, C-terminal domain HTH_5 PF01022.20 EHT99787.1 - 0.16 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family MFS_1 PF07690.16 EHT99788.1 - 7.4e-28 97.5 46.1 6.6e-22 77.9 31.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EHT99788.1 - 2.5e-07 30.0 30.4 0.021 13.7 0.1 4.0 1 1 3 4 4 4 4 Sugar (and other) transporter MFS_3 PF05977.13 EHT99788.1 - 1.3e-06 27.1 2.5 1.3e-06 27.1 2.5 2.2 2 0 0 2 2 2 1 Transmembrane secretion effector MFS_1_like PF12832.7 EHT99788.1 - 6.8e-06 25.2 26.4 7.5e-05 21.7 9.8 2.2 1 1 1 2 2 2 2 MFS_1 like family MFS_4 PF06779.14 EHT99788.1 - 7.8e-05 22.1 28.1 9.7e-05 21.8 28.1 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Spore_YhaL PF14147.6 EHT99788.1 - 0.12 12.0 3.1 0.38 10.5 0.1 2.7 2 0 0 2 2 2 0 Sporulation protein YhaL DUF1272 PF06906.11 EHT99789.1 - 1e-30 105.6 9.7 1.2e-30 105.3 9.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) zf-C4_Topoisom PF01396.19 EHT99789.1 - 0.02 14.7 0.3 0.02 14.7 0.3 2.4 3 1 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger zf_Rg PF17915.1 EHT99789.1 - 0.057 12.8 1.6 0.057 12.8 1.6 2.2 2 1 0 2 2 2 0 Reverse gyrase zinc finger zf-C2HC5 PF06221.13 EHT99789.1 - 0.15 12.0 8.7 1.2 9.2 4.0 2.6 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-RING_4 PF14570.6 EHT99789.1 - 0.4 10.5 11.0 0.55 10.1 11.0 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF983 PF06170.12 EHT99789.1 - 0.8 10.2 5.6 7.5 7.0 1.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF983) Zn-ribbon_8 PF09723.10 EHT99789.1 - 0.91 9.7 10.3 0.68 10.1 6.6 2.3 2 1 0 2 2 2 0 Zinc ribbon domain PhnA_Zn_Ribbon PF08274.12 EHT99789.1 - 0.98 9.4 10.8 3.7 7.6 0.1 3.2 2 1 0 2 2 2 0 PhnA Zinc-Ribbon Methyltr_RsmB-F PF01189.17 EHT99790.1 - 3.8e-48 163.8 0.0 6e-48 163.2 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EHT99790.1 - 8.2e-26 90.3 0.0 1.9e-25 89.2 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF Methyltranf_PUA PF13636.6 EHT99790.1 - 8.6e-11 41.7 0.0 1.6e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 RNA-binding PUA-like domain of methyltransferase RsmF FtsJ PF01728.19 EHT99790.1 - 0.00051 20.2 0.0 0.00085 19.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 EHT99790.1 - 0.0023 17.7 0.0 0.0039 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EHT99790.1 - 0.0059 16.3 0.0 0.0094 15.6 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 EHT99790.1 - 0.049 14.4 0.0 0.47 11.2 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain TRM PF02005.16 EHT99790.1 - 0.083 12.0 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase GntR PF00392.21 EHT99790.1 - 0.16 11.7 0.0 0.48 10.1 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family MlaD PF02470.20 EHT99791.1 - 2.6e-68 226.3 10.4 5.1e-16 58.7 0.1 7.3 7 0 0 7 7 7 7 MlaD protein PqiA PF04403.13 EHT99792.1 - 5.6e-82 273.2 34.2 3.1e-44 150.5 12.6 2.0 2 0 0 2 2 2 2 Paraquat-inducible protein A HypA PF01155.19 EHT99792.1 - 0.0016 18.4 0.5 0.52 10.4 0.1 2.5 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_4 PF13717.6 EHT99792.1 - 0.0021 17.9 6.4 0.015 15.2 2.1 2.7 2 0 0 2 2 2 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 EHT99792.1 - 0.0033 16.8 3.5 3.3 7.2 0.2 3.5 3 0 0 3 3 3 1 zinc-ribbon domain zf-LITAF-like PF10601.9 EHT99792.1 - 0.0033 17.7 4.5 0.32 11.3 0.0 4.1 3 0 0 3 3 3 1 LITAF-like zinc ribbon domain zf_UBZ PF18439.1 EHT99792.1 - 0.004 16.7 4.7 1 9.0 0.1 3.5 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger Tmemb_55A PF09788.9 EHT99792.1 - 0.0068 15.5 6.5 0.2 10.7 0.1 3.0 2 1 0 3 3 3 2 Transmembrane protein 55A DZR PF12773.7 EHT99792.1 - 0.007 16.4 7.8 0.74 9.9 1.0 2.6 2 0 0 2 2 2 2 Double zinc ribbon Zn_Tnp_IS91 PF14319.6 EHT99792.1 - 0.039 14.0 2.0 4.7 7.3 0.1 2.3 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-RING_4 PF14570.6 EHT99792.1 - 0.054 13.3 0.9 0.054 13.3 0.9 3.0 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain zinc-ribbons_6 PF07191.12 EHT99792.1 - 0.086 12.8 6.6 2 8.4 0.8 2.4 2 0 0 2 2 2 0 zinc-ribbons XAF1_C PF18608.1 EHT99792.1 - 0.14 11.7 4.9 0.063 12.8 1.4 2.1 2 0 0 2 2 2 0 XIAP-associated factor 1 C-terminal domain IBR PF01485.21 EHT99792.1 - 0.14 12.4 4.8 0.13 12.5 0.5 2.2 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zinc_ribbon_5 PF13719.6 EHT99792.1 - 0.41 10.4 7.9 0.28 11.0 2.5 2.5 2 1 0 2 2 2 0 zinc-ribbon domain TackOD1 PF18551.1 EHT99792.1 - 0.99 9.0 3.8 6.4 6.4 0.3 2.3 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 zf-TFIIB PF13453.6 EHT99792.1 - 1 8.7 5.9 17 4.8 0.2 3.4 3 0 0 3 3 3 0 Transcription factor zinc-finger zinc_ribbon_15 PF17032.5 EHT99792.1 - 1.3 9.8 4.2 12 6.8 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon family FYVE PF01363.21 EHT99792.1 - 1.8 8.8 10.0 1.6 8.9 0.3 3.1 2 1 1 3 3 3 0 FYVE zinc finger Zn-ribbon_8 PF09723.10 EHT99792.1 - 2.5 8.3 11.1 0.42 10.8 1.3 2.8 2 1 1 3 3 3 0 Zinc ribbon domain DNA_ligase_ZBD PF03119.16 EHT99792.1 - 3.6 7.7 7.2 30 4.7 0.5 3.3 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain zf-HIT PF04438.16 EHT99792.1 - 8.7 6.3 10.9 6.1 6.8 1.3 3.2 3 0 0 3 3 3 0 HIT zinc finger GAF_2 PF13185.6 EHT99793.1 - 8.7e-11 42.3 0.0 1.2e-10 41.8 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 EHT99793.1 - 1e-06 29.4 0.0 1.2e-06 29.2 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 EHT99793.1 - 0.0073 16.7 0.0 0.01 16.2 0.0 1.3 1 0 0 1 1 1 1 GAF domain ProQ PF04352.13 EHT99794.1 - 9.5e-42 141.4 0.1 2e-41 140.3 0.0 1.5 2 0 0 2 2 2 1 ProQ/FINO family ProQ_C PF17516.2 EHT99794.1 - 1e-25 88.9 0.3 1.6e-25 88.3 0.3 1.3 1 0 0 1 1 1 1 ProQ C-terminal domain RNase_II_C_S1 PF18614.1 EHT99794.1 - 0.046 13.7 0.1 0.25 11.3 0.1 2.1 2 0 0 2 2 2 0 RNase II-type exonuclease C-terminal S1 domain S1 PF00575.23 EHT99794.1 - 0.069 13.5 0.1 0.4 11.0 0.1 2.1 1 1 1 2 2 2 0 S1 RNA binding domain Menin PF05053.13 EHT99794.1 - 2.5 6.3 4.8 3 6.1 4.8 1.1 1 0 0 1 1 1 0 Menin TSP_NTD PF17804.1 EHT99795.1 - 5e-58 196.6 4.7 5e-58 196.6 4.7 2.0 2 0 0 2 2 2 1 Tail specific protease N-terminal domain Peptidase_S41 PF03572.18 EHT99795.1 - 7.1e-52 175.3 0.1 1.2e-51 174.6 0.1 1.4 1 0 0 1 1 1 1 Peptidase family S41 DUF3340 PF11818.8 EHT99795.1 - 1.9e-41 141.8 7.6 3.5e-41 140.9 7.6 1.5 1 0 0 1 1 1 1 C-terminal domain of tail specific protease (DUF3340) PDZ PF00595.24 EHT99795.1 - 2.4e-14 53.4 0.3 5e-14 52.4 0.3 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EHT99795.1 - 3.4e-06 26.8 0.6 1.2e-05 25.1 0.6 1.9 1 1 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EHT99795.1 - 0.0027 18.0 0.3 0.0078 16.5 0.3 1.8 1 0 0 1 1 1 1 PDZ domain Peptidase_M48 PF01435.18 EHT99796.1 - 1.2e-39 136.1 0.2 2.1e-39 135.3 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 EHT99796.1 - 3.4e-05 23.2 0.0 6.5e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 BlaR1 peptidase M56 SprT-like PF10263.9 EHT99796.1 - 0.0021 17.9 0.0 0.0033 17.2 0.0 1.3 1 0 0 1 1 1 1 SprT-like family Peptidase_M1 PF01433.20 EHT99796.1 - 0.013 15.0 0.1 0.019 14.5 0.1 1.2 1 0 0 1 1 1 0 Peptidase family M1 domain Myc_target_1 PF15179.6 EHT99796.1 - 0.02 14.8 0.6 0.045 13.7 0.5 1.6 1 1 0 1 1 1 0 Myc target protein 1 Cation_ATPase_C PF00689.21 EHT99796.1 - 0.1 12.3 0.2 0.1 12.3 0.2 2.2 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus MFS_1 PF07690.16 EHT99797.1 - 0.00031 19.8 4.8 0.00035 19.6 4.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily FUSC_2 PF13515.6 EHT99797.1 - 0.042 14.0 2.2 0.053 13.6 2.1 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein-like Yip1 PF04893.17 EHT99797.1 - 0.097 12.4 3.5 0.12 12.1 3.5 1.0 1 0 0 1 1 1 0 Yip1 domain HTH_Tnp_1 PF01527.20 EHT99798.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT99798.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT99798.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT99798.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHT99799.1 - 7.4e-39 131.7 0.0 8.3e-39 131.6 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein LZ_Tnp_IS66 PF13007.7 EHT99800.1 - 9.6e-13 48.7 9.0 1.6e-12 48.0 9.0 1.4 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHT99800.1 - 0.00095 19.0 6.2 0.0012 18.7 6.2 1.0 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B Csm1_N PF18504.1 EHT99800.1 - 0.0013 19.0 6.1 0.014 15.8 1.2 2.5 1 1 1 2 2 2 1 Csm1 N-terminal domain FUSC PF04632.12 EHT99800.1 - 0.0025 16.5 6.8 0.0026 16.4 6.8 1.0 1 0 0 1 1 1 1 Fusaric acid resistance protein family LXG PF04740.12 EHT99800.1 - 0.0028 17.4 2.9 0.034 13.9 0.5 2.0 1 1 1 2 2 2 1 LXG domain of WXG superfamily Phage_HK97_TLTM PF06120.11 EHT99800.1 - 0.0042 16.3 2.5 0.0052 16.0 2.5 1.2 1 0 0 1 1 1 1 Tail length tape measure protein ERM PF00769.19 EHT99800.1 - 0.01 15.6 10.8 0.013 15.4 10.8 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Tho2 PF11262.8 EHT99800.1 - 0.015 14.5 2.3 0.016 14.4 1.5 1.3 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DHR10 PF18595.1 EHT99800.1 - 0.027 14.5 10.9 0.037 14.1 10.9 1.1 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain TMPIT PF07851.13 EHT99800.1 - 0.028 13.7 1.7 0.034 13.4 1.7 1.0 1 0 0 1 1 1 0 TMPIT-like protein Troponin PF00992.20 EHT99800.1 - 0.029 14.7 6.2 0.051 13.9 6.2 1.3 1 1 0 1 1 1 0 Troponin Exonuc_VII_L PF02601.15 EHT99800.1 - 0.032 13.8 3.9 0.036 13.6 3.9 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit RD3 PF14473.6 EHT99800.1 - 0.042 13.7 2.3 0.057 13.2 2.3 1.2 1 0 0 1 1 1 0 RD3 protein PCRF PF03462.18 EHT99800.1 - 0.072 13.0 3.5 0.092 12.6 3.5 1.1 1 0 0 1 1 1 0 PCRF domain ATG16 PF08614.11 EHT99800.1 - 0.084 13.1 10.2 0.35 11.1 2.1 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF3145 PF11343.8 EHT99800.1 - 0.093 12.3 0.6 0.24 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3145) HAUS-augmin3 PF14932.6 EHT99800.1 - 0.11 12.0 7.9 0.3 10.6 7.9 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF1192 PF06698.11 EHT99800.1 - 0.14 12.2 8.8 0.53 10.4 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Mt_ATP-synt_D PF05873.12 EHT99800.1 - 0.16 11.8 3.4 1.4 8.7 0.1 2.0 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) DUF948 PF06103.11 EHT99800.1 - 0.16 12.2 1.7 12 6.3 0.1 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Lebercilin PF15619.6 EHT99800.1 - 0.18 11.5 10.9 0.36 10.4 10.9 1.5 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease HalX PF08663.10 EHT99800.1 - 0.18 12.2 7.2 0.047 14.0 3.1 2.0 2 0 0 2 2 2 0 HalX domain FapA PF03961.13 EHT99800.1 - 0.25 9.9 1.9 0.3 9.6 1.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A OmpH PF03938.14 EHT99800.1 - 0.26 11.6 8.0 0.35 11.2 8.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4446 PF14584.6 EHT99800.1 - 0.36 10.8 3.2 0.37 10.8 1.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) G-gamma PF00631.22 EHT99800.1 - 0.38 10.8 3.7 3.6 7.7 0.0 2.6 2 1 1 3 3 2 0 GGL domain USP8_interact PF08941.10 EHT99800.1 - 0.51 10.1 4.5 1.1 9.0 4.5 1.5 1 1 1 2 2 2 0 USP8 interacting SlyX PF04102.12 EHT99800.1 - 0.55 10.9 10.5 4.7e+02 1.5 10.5 2.8 1 1 0 1 1 1 0 SlyX TMF_DNA_bd PF12329.8 EHT99800.1 - 0.59 10.2 9.2 1.1 9.3 0.7 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF641 PF04859.12 EHT99800.1 - 0.87 9.9 8.2 0.39 11.0 1.8 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) MerR-DNA-bind PF09278.11 EHT99800.1 - 3.7 8.1 13.5 4.7 7.8 2.1 2.6 2 1 0 2 2 2 0 MerR, DNA binding HAUS6_N PF14661.6 EHT99800.1 - 4 7.0 8.7 11 5.5 8.7 1.7 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus ZapB PF06005.12 EHT99800.1 - 5.1 7.6 11.0 72 3.9 10.6 2.5 1 1 0 1 1 1 0 Cell division protein ZapB DDE_3 PF13358.6 EHT99801.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHT99801.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHT99801.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHT99801.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHT99801.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHT99801.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHT99801.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHT99801.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 HlyD_3 PF13437.6 EHT99802.1 - 1e-19 71.2 1.4 4.6e-15 56.2 0.1 2.9 3 0 0 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 EHT99802.1 - 8.5e-13 47.9 1.8 1.1e-10 41.2 0.2 3.6 3 0 0 3 3 3 1 Biotin-lipoyl like HlyD_D23 PF16576.5 EHT99802.1 - 3.2e-12 46.1 2.4 1.2e-09 37.7 2.0 3.0 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD PF00529.20 EHT99802.1 - 5.4e-10 39.0 0.2 8.7e-10 38.4 0.2 1.3 1 0 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl PF00364.22 EHT99802.1 - 0.00029 20.6 2.2 0.031 14.1 0.2 3.0 3 0 0 3 3 3 1 Biotin-requiring enzyme OEP PF02321.18 EHT99802.1 - 0.0012 18.6 3.9 0.0025 17.6 3.9 1.5 1 0 0 1 1 1 1 Outer membrane efflux protein Trans_reg_C PF00486.28 EHT99802.1 - 0.27 11.4 1.8 4.9 7.3 0.0 3.3 3 1 1 4 4 4 0 Transcriptional regulatory protein, C terminal OEP PF02321.18 EHT99803.1 - 6.2e-40 137.0 42.8 9.9e-24 84.2 13.3 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein Big_6 PF17936.1 EHT99804.1 - 5.5e-22 77.8 128.9 5e-05 23.5 6.3 11.8 12 0 0 12 12 12 9 Bacterial Ig domain Big_3_2 PF12245.8 EHT99804.1 - 4.4e-08 33.4 22.4 2.2 8.5 0.0 8.8 8 1 0 9 9 9 5 Bacterial Ig-like domain DUF4625 PF15418.6 EHT99804.1 - 1.2e-06 28.8 0.2 16 5.8 0.0 7.5 8 0 0 8 8 8 1 Domain of unknown function (DUF4625) DUF1905 PF08922.11 EHT99804.1 - 6.5e-06 26.1 9.7 0.28 11.3 0.0 6.3 6 0 0 6 6 6 2 Domain of unknown function (DUF1905) Cyanate_lyase PF02560.14 EHT99804.1 - 1.3e-05 24.9 0.2 0.44 10.4 0.0 4.5 5 0 0 5 5 5 2 Cyanate lyase C-terminal domain OapA PF04225.12 EHT99804.1 - 0.11 12.6 2.4 7.6 6.7 0.0 4.6 6 0 0 6 6 6 0 Opacity-associated protein A LysM-like domain Big_6 PF17936.1 EHT99805.1 - 1.5e-11 44.4 72.0 0.003 17.8 8.1 7.0 6 1 0 6 6 6 5 Bacterial Ig domain hemP PF10636.9 EHT99805.1 - 0.00033 20.4 0.9 5.4 6.9 0.1 4.7 5 0 0 5 5 5 1 Hemin uptake protein hemP DUF1905 PF08922.11 EHT99805.1 - 0.0013 18.8 3.7 20 5.3 0.1 5.2 4 0 0 4 4 4 0 Domain of unknown function (DUF1905) HZS_alpha PF18582.1 EHT99805.1 - 0.0023 18.4 6.6 50 4.4 0.0 5.6 6 0 0 6 6 5 0 Hydrazine synthase alpha subunit middle domain PriA_3primeBD PF17764.1 EHT99805.1 - 0.0072 16.2 1.4 29 4.6 0.0 3.8 4 0 0 4 4 4 0 3′ DNA-binding domain (3′BD) FokI_C PF02980.16 EHT99805.1 - 0.012 15.7 1.1 38 4.3 0.0 4.1 4 0 0 4 4 4 0 Restriction endonuclease FokI, catalytic domain DUF4772 PF15997.5 EHT99805.1 - 0.066 13.8 5.8 30 5.3 0.0 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF4772) RAMA PF18755.1 EHT99805.1 - 0.13 12.7 9.2 9.4 6.7 0.1 4.8 5 0 0 5 5 5 0 Restriction Enzyme Adenine Methylase Associated ABC_trans_aux PF03886.13 EHT99805.1 - 0.2 11.3 13.2 4.3 6.9 0.8 3.9 3 0 0 3 3 3 0 ABC-type transport auxiliary lipoprotein component RcpC PF16976.5 EHT99805.1 - 0.65 10.1 21.6 0.89 9.6 1.9 3.9 3 0 0 3 3 3 0 Flp pilus assembly protein RcpC/CpaB BPL_C PF02237.17 EHT99805.1 - 1.3 9.0 11.8 25 4.9 0.2 4.6 4 0 0 4 4 4 0 Biotin protein ligase C terminal domain Lyx_isomer PF07385.12 EHT99805.1 - 1.3 8.2 4.4 15 4.8 0.0 3.3 5 0 0 5 5 5 0 D-lyxose isomerase AraC_binding_2 PF14525.6 EHT99805.1 - 5.5 6.7 13.5 12 5.6 0.2 4.2 5 0 0 5 5 5 0 AraC-binding-like domain Big_6 PF17936.1 EHT99806.1 - 2e-69 229.8 255.0 8.1e-07 29.2 5.5 23.6 23 0 0 23 23 22 22 Bacterial Ig domain DUF4625 PF15418.6 EHT99806.1 - 1.4e-20 73.8 9.7 0.15 12.3 0.0 14.5 19 0 0 19 19 19 6 Domain of unknown function (DUF4625) Big_3_3 PF13750.6 EHT99806.1 - 1.1e-17 64.1 99.7 0.00038 20.1 1.7 18.7 14 7 5 19 19 19 11 Bacterial Ig-like domain (group 3) Big_3_4 PF13754.6 EHT99806.1 - 4.5e-11 42.4 10.7 1.7 8.4 0.0 10.3 11 0 0 11 11 11 4 Domain of unknown function MFS_1 PF07690.16 EHT99806.1 - 2.9e-08 33.1 26.9 6.1e-08 32.0 26.9 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Big_3_2 PF12245.8 EHT99806.1 - 1.7e-06 28.3 74.2 0.032 14.5 2.6 16.8 19 1 0 20 20 20 5 Bacterial Ig-like domain DUF4998 PF16389.5 EHT99806.1 - 5.9e-06 26.0 1.8 0.5 9.9 0.0 6.7 8 0 0 8 8 8 1 Domain of unknown function HYR PF02494.16 EHT99806.1 - 0.00042 20.6 63.2 3.2 8.1 0.0 17.7 20 1 0 20 20 19 3 HYR domain Y_Y_Y PF07495.13 EHT99806.1 - 0.00063 19.6 1.9 1.7 8.6 0.0 6.6 8 0 0 8 8 8 1 Y_Y_Y domain DUF1905 PF08922.11 EHT99806.1 - 0.0014 18.6 19.0 32 4.7 0.0 13.6 17 0 0 17 17 17 0 Domain of unknown function (DUF1905) bMG5 PF17972.1 EHT99806.1 - 0.34 11.3 10.1 5.7 7.3 0.0 7.1 9 0 0 9 9 9 0 Bacterial Alpha-2-macroglobulin MG5 domain GatD_N PF18195.1 EHT99806.1 - 2 7.8 5.2 27 4.2 0.0 4.9 6 0 0 6 6 6 0 GatD N-terminal domain RcsD_ABL PF16359.5 EHT99807.1 - 2.5e-36 123.9 0.0 9.2e-36 122.1 0.0 2.0 1 0 0 1 1 1 1 RcsD-ABL domain HATPase_c PF02518.26 EHT99807.1 - 1.8e-11 44.6 0.0 3.9e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Hpt PF01627.23 EHT99807.1 - 1.8e-11 44.1 0.3 1.6e-10 41.1 0.0 2.7 2 0 0 2 2 2 1 Hpt domain HisKA PF00512.25 EHT99807.1 - 0.011 15.7 6.1 0.015 15.3 4.0 2.5 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 EHT99808.1 - 8.2e-25 87.2 0.1 1.3e-24 86.5 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 EHT99808.1 - 1.3e-18 66.3 0.2 2.1e-18 65.6 0.2 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 EHT99808.1 - 7e-05 22.4 0.2 0.00016 21.3 0.2 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EHT99808.1 - 7.2e-05 22.2 0.1 0.00016 21.1 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 EHT99808.1 - 0.00073 19.2 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 EHT99808.1 - 0.0008 19.1 0.0 0.0041 16.9 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain DUF2121 PF09894.9 EHT99808.1 - 0.042 13.4 0.0 0.1 12.2 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2121) Glycos_transf_N PF04413.16 EHT99808.1 - 0.084 12.5 0.0 25 4.5 0.0 2.9 2 1 1 3 3 3 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) HTH_29 PF13551.6 EHT99808.1 - 0.11 12.6 0.0 0.59 10.2 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn helix DUF2357 PF09823.9 EHT99808.1 - 0.11 11.7 0.0 0.28 10.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2357) Terminase_5 PF06056.12 EHT99808.1 - 0.17 11.8 0.0 0.63 10.0 0.0 1.8 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) Response_reg PF00072.24 EHT99809.1 - 9.3e-31 106.3 0.3 2.9e-30 104.7 0.1 2.0 2 0 0 2 2 2 1 Response regulator receiver domain RcsC PF09456.10 EHT99809.1 - 1.3e-28 98.8 0.4 1.6e-27 95.3 0.0 2.9 3 0 0 3 3 3 1 RcsC Alpha-Beta-Loop (ABL) HATPase_c PF02518.26 EHT99809.1 - 2.3e-27 95.7 0.0 4.8e-27 94.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EHT99809.1 - 8.5e-16 57.8 0.4 4.3e-15 55.5 0.1 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain DNA_topoisoIV PF00521.20 EHT99810.1 - 3.6e-156 520.4 0.0 4.5e-156 520.0 0.0 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 EHT99810.1 - 5.9e-78 256.2 11.7 1.1e-13 50.5 0.1 6.6 7 0 0 7 7 7 6 DNA gyrase C-terminal domain, beta-propeller Methyltransf_23 PF13489.6 EHT99811.1 - 1.9e-23 83.1 0.0 2.7e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EHT99811.1 - 6e-20 71.7 0.1 9.9e-20 71.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EHT99811.1 - 6.3e-18 65.3 0.1 9.6e-18 64.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EHT99811.1 - 2.6e-15 56.5 0.0 3.4e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EHT99811.1 - 9.8e-15 55.1 0.0 1.6e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 EHT99811.1 - 4.9e-09 36.1 0.0 5.8e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.20 EHT99811.1 - 1.3e-08 34.5 0.0 1.9e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EHT99811.1 - 2.2e-08 33.7 0.0 2.7e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 EHT99811.1 - 4e-06 26.5 0.0 5.4e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EHT99811.1 - 5.3e-06 26.1 0.1 8.2e-06 25.5 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 EHT99811.1 - 0.00011 21.2 0.0 0.00016 20.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MetW PF07021.12 EHT99811.1 - 0.0027 17.3 0.0 0.0041 16.7 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 EHT99811.1 - 0.0065 16.5 0.0 0.0098 15.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 EHT99811.1 - 0.03 13.7 0.2 0.11 11.8 0.2 1.8 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_18 PF12847.7 EHT99811.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF4390 PF14334.6 EHT99811.1 - 0.16 11.4 0.0 0.47 9.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4390) DREV PF05219.12 EHT99811.1 - 0.22 10.6 0.0 0.51 9.4 0.0 1.5 1 1 0 1 1 1 0 DREV methyltransferase Ribonuc_red_lgC PF02867.15 EHT99812.1 - 5.5e-123 411.3 0.0 1.1e-120 403.7 0.0 2.5 2 1 0 2 2 2 1 Ribonucleotide reductase, barrel domain ATP-cone PF03477.16 EHT99812.1 - 7.3e-16 58.5 0.1 1.9e-15 57.2 0.1 1.8 1 0 0 1 1 1 1 ATP cone domain Ribonuc_red_lgN PF00317.21 EHT99812.1 - 1.1e-13 51.0 0.1 2.4e-13 49.9 0.1 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain Ribonuc_red_sm PF00268.21 EHT99813.1 - 3.8e-49 167.7 1.6 4.9e-49 167.3 1.6 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Flavodoxin_5 PF12724.7 EHT99813.1 - 0.15 12.3 0.1 0.83 9.9 0.0 2.0 2 0 0 2 2 2 0 Flavodoxin domain Fer2 PF00111.27 EHT99814.1 - 4.1e-10 39.5 3.7 4.6e-10 39.3 3.7 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 EHT99814.1 - 0.029 14.4 0.2 0.033 14.2 0.2 1.2 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Ribonuc_L-PSP PF01042.21 EHT99815.1 - 4.6e-29 100.9 0.0 5.1e-29 100.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP TetR_N PF00440.23 EHT99816.1 - 2.2e-14 53.0 2.0 2.2e-14 53.0 2.0 2.5 3 0 0 3 3 3 1 Bacterial regulatory proteins, tetR family TetR_C_7 PF14246.6 EHT99816.1 - 0.021 14.9 0.5 0.052 13.6 0.5 1.8 1 1 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal domain AphA_like PF14557.6 EHT99816.1 - 0.033 13.9 0.4 1.8 8.3 0.3 2.3 2 1 0 2 2 2 0 Putative AphA-like transcriptional regulator TetR_C_24 PF17932.1 EHT99816.1 - 0.033 14.4 0.2 1.7 9.0 0.0 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain MoCF_biosynth PF00994.24 EHT99817.1 - 7.7e-31 106.7 0.0 1.5e-30 105.8 0.0 1.5 1 0 0 1 1 1 1 Probable molybdopterin binding domain CinA_KH PF18146.1 EHT99817.1 - 0.00012 22.2 0.0 0.00028 21.0 0.0 1.6 1 0 0 1 1 1 1 Damage-inducible protein CinA KH domain CinA PF02464.17 EHT99817.1 - 0.048 13.2 0.1 1 8.9 0.0 2.4 2 0 0 2 2 2 0 Competence-damaged protein DUF883 PF05957.13 EHT99818.1 - 5.5e-27 94.2 0.1 7e-27 93.9 0.1 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 EHT99818.1 - 0.0076 16.8 8.9 0.29 11.7 1.2 2.5 2 1 1 3 3 3 3 YtxH-like protein Apolipoprotein PF01442.18 EHT99818.1 - 0.014 15.3 0.2 0.015 15.2 0.2 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4449 PF14613.6 EHT99818.1 - 0.023 14.8 0.3 0.027 14.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) DUF2884 PF11101.8 EHT99818.1 - 0.1 12.1 0.2 0.12 11.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) MdoG PF04349.12 EHT99819.1 - 1.1e-179 598.4 0.0 1.2e-179 598.2 0.0 1.0 1 0 0 1 1 1 1 Periplasmic glucan biosynthesis protein, MdoG EpoR_lig-bind PF09067.10 EHT99819.1 - 0.05 13.8 0.3 1.1 9.5 0.0 2.5 2 0 0 2 2 2 0 Erythropoietin receptor, ligand binding Acetyltransf_10 PF13673.7 EHT99820.1 - 5.9e-15 55.3 0.0 6.9e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EHT99820.1 - 1.5e-06 28.6 0.1 2.3e-06 27.9 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EHT99820.1 - 7.1e-05 23.0 0.0 8.6e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Abhydrolase_3 PF07859.13 EHT99821.1 - 2.2e-09 37.5 2.6 3.8e-08 33.5 2.6 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EHT99821.1 - 1.3e-08 34.6 1.8 1.3e-07 31.3 1.8 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 EHT99821.1 - 0.0037 17.2 0.2 0.013 15.4 0.2 1.9 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 EHT99821.1 - 0.0052 16.4 0.3 0.013 15.0 0.3 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 EHT99821.1 - 0.014 14.6 0.2 0.063 12.5 0.0 2.0 1 1 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EHT99821.1 - 0.017 14.8 0.1 0.032 13.9 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold FSH1 PF03959.13 EHT99821.1 - 0.025 14.3 0.1 0.054 13.1 0.1 1.4 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.10 EHT99821.1 - 0.084 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein Proton_antipo_M PF00361.20 EHT99822.1 - 4.8e-85 285.3 23.8 4.8e-85 285.3 23.8 1.8 2 0 0 2 2 2 1 Proton-conducting membrane transporter NADHdeh_related PF10125.9 EHT99822.1 - 0.00015 21.3 4.2 0.00015 21.3 4.2 2.2 2 0 0 2 2 2 1 NADH dehydrogenase I, subunit N related protein Proton_antipo_M PF00361.20 EHT99823.1 - 5.4e-70 235.9 27.1 1e-69 235.0 27.1 1.4 1 0 0 1 1 1 1 Proton-conducting membrane transporter Proton_antipo_M PF00361.20 EHT99824.1 - 3.4e-97 325.2 22.1 3.4e-97 325.2 22.1 2.5 3 0 0 3 3 3 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 EHT99824.1 - 3e-23 81.6 2.0 3e-23 81.6 2.0 2.9 2 0 0 2 2 2 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Oxidored_q2 PF00420.24 EHT99825.1 - 2.5e-20 72.0 7.8 3e-20 71.8 7.8 1.0 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L ATP1G1_PLM_MAT8 PF02038.16 EHT99825.1 - 0.0087 15.5 0.4 0.02 14.3 0.4 1.6 1 0 0 1 1 1 1 ATP1G1/PLM/MAT8 family DUF5392 PF17370.2 EHT99825.1 - 0.22 11.6 1.2 0.24 11.5 1.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5392) Oxidored_q3 PF00499.20 EHT99826.1 - 1.6e-35 121.9 16.3 2e-35 121.6 16.3 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF4199 PF13858.6 EHT99826.1 - 0.023 15.1 3.6 0.023 15.1 3.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) DUF4079 PF13301.6 EHT99826.1 - 0.15 12.2 6.6 0.25 11.5 5.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) DUF5379 PF17350.2 EHT99826.1 - 0.32 11.3 9.2 0.14 12.5 5.9 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5379) DUF2109 PF09882.9 EHT99826.1 - 2.4 8.2 10.0 0.15 12.1 4.4 2.0 2 1 0 2 2 2 0 Predicted membrane protein (DUF2109) MpPF26 PF07666.11 EHT99826.1 - 9.7 6.3 12.2 0.12 12.4 1.7 2.4 2 1 1 3 3 3 0 M penetrans paralogue family 26 Fer4 PF00037.27 EHT99827.1 - 5.5e-14 51.3 16.9 7e-09 35.1 0.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EHT99827.1 - 8.8e-12 45.4 10.7 1.4e-11 44.8 10.7 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EHT99827.1 - 3.8e-10 40.6 5.3 0.00017 22.4 0.0 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 EHT99827.1 - 9.8e-10 38.4 8.7 0.00016 21.7 4.7 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EHT99827.1 - 1.5e-09 37.8 19.2 1.9e-06 27.9 12.1 1.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 EHT99827.1 - 3.7e-09 36.9 1.3 0.0021 18.4 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EHT99827.1 - 7.6e-08 32.4 10.2 2.8e-07 30.6 10.7 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 EHT99827.1 - 1.4e-07 31.9 5.0 0.0051 17.3 0.6 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 EHT99827.1 - 7.4e-06 25.7 12.7 0.01 15.8 0.9 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 EHT99827.1 - 5.3e-05 23.1 17.3 0.0046 17.0 0.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 EHT99827.1 - 0.00074 19.8 13.1 0.068 13.7 1.2 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_3 PF12798.7 EHT99827.1 - 0.0087 16.9 3.6 0.0087 16.9 3.6 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_13 PF13370.6 EHT99827.1 - 0.064 13.8 12.2 0.53 10.9 1.4 2.6 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I ETF_QO PF05187.13 EHT99827.1 - 0.073 13.2 5.4 0.4 10.8 1.6 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_18 PF13746.6 EHT99827.1 - 0.7 10.1 11.5 87 3.4 11.7 2.2 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 EHT99827.1 - 0.82 10.6 14.4 3.4 8.6 2.3 2.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain NADHdh PF00146.21 EHT99828.1 - 2.4e-118 394.8 18.6 2.8e-118 394.6 18.6 1.0 1 0 0 1 1 1 1 NADH dehydrogenase NADH-G_4Fe-4S_3 PF10588.9 EHT99829.1 - 4.7e-15 54.9 0.2 1.1e-14 53.6 0.2 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.6 EHT99829.1 - 5.1e-12 45.7 3.6 7.7e-11 41.9 0.1 3.4 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain Molybdop_Fe4S4 PF04879.16 EHT99829.1 - 1.2e-10 41.3 0.2 3.1e-10 39.9 0.2 1.8 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain Fer2 PF00111.27 EHT99829.1 - 2e-09 37.3 1.3 1.2e-08 34.8 0.1 2.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Molybdopterin PF00384.22 EHT99829.1 - 7.5e-09 35.0 0.0 4.9e-08 32.3 0.0 2.0 2 0 0 2 2 2 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 EHT99829.1 - 3.6e-08 33.4 0.0 9.5e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain TPP_enzyme_M PF00205.22 EHT99829.1 - 0.0066 16.2 2.8 0.053 13.3 1.8 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Fer4_6 PF12837.7 EHT99829.1 - 3.6 7.8 9.2 0.25 11.5 0.6 3.2 3 0 0 3 3 3 0 4Fe-4S binding domain Complex1_51K PF01512.17 EHT99830.1 - 1.2e-50 171.4 0.0 1.6e-50 170.9 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 EHT99830.1 - 1.2e-26 92.6 0.0 1.9e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 EHT99830.1 - 6.3e-07 29.2 0.1 1.5e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 SLBB domain CP12 PF02672.15 EHT99830.1 - 0.1 13.3 0.0 0.24 12.2 0.0 1.5 1 0 0 1 1 1 0 CP12 domain 2Fe-2S_thioredx PF01257.19 EHT99831.1 - 3.1e-50 169.8 0.0 3.6e-50 169.6 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Complex1_49kDa PF00346.19 EHT99832.1 - 4e-102 341.0 0.0 5.2e-102 340.6 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Complex1_30kDa PF00329.19 EHT99832.1 - 1.7e-41 141.7 0.4 3.7e-41 140.6 0.2 1.7 2 0 0 2 2 2 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Oxidored_q6 PF01058.22 EHT99833.1 - 3.6e-21 75.4 0.0 5e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Oxidored_q4 PF00507.19 EHT99834.1 - 7.3e-32 109.5 0.6 7.3e-32 109.5 0.6 1.8 1 1 1 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Phage_Coat_Gp8 PF05371.12 EHT99834.1 - 0.11 12.3 0.8 0.24 11.2 0.1 1.9 2 0 0 2 2 2 0 Phage major coat protein, Gp8 K_trans PF02705.16 EHT99834.1 - 2.6 6.4 8.2 0.087 11.3 2.1 1.5 2 0 0 2 2 2 0 K+ potassium transporter LysR_substrate PF03466.20 EHT99835.1 - 4.3e-28 98.1 0.1 7.8e-28 97.3 0.1 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EHT99835.1 - 4.2e-18 65.0 1.5 7.9e-18 64.2 1.5 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MGS PF02142.22 EHT99835.1 - 0.075 13.2 0.1 0.73 10.1 0.1 2.3 1 1 0 1 1 1 0 MGS-like domain Aminotran_1_2 PF00155.21 EHT99836.1 - 5e-47 160.8 0.0 6.1e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EHT99836.1 - 0.00012 21.5 0.0 0.00019 20.9 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EHT99836.1 - 0.0042 16.1 0.0 0.0065 15.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EHT99836.1 - 0.084 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase HD_2 PF12917.7 EHT99837.1 - 3.6e-77 258.2 2.2 4e-77 258.1 2.2 1.0 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD_3 PF13023.6 EHT99837.1 - 9e-20 71.2 0.9 1.1e-19 70.9 0.9 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.22 EHT99837.1 - 3.6e-08 33.7 1.2 5e-08 33.2 1.2 1.2 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 EHT99837.1 - 0.044 13.3 0.1 0.065 12.7 0.1 1.3 1 1 0 1 1 1 0 HDOD domain HAD_2 PF13419.6 EHT99838.1 - 1.3e-25 90.6 0.0 1.5e-25 90.3 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EHT99838.1 - 3.8e-16 60.0 0.2 1.4e-14 54.9 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EHT99838.1 - 3.4e-07 30.9 0.0 4e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EHT99838.1 - 0.00039 20.4 0.0 0.00074 19.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EHT99838.1 - 0.00056 20.0 0.0 0.0022 18.1 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase YfbU PF03887.14 EHT99839.1 - 7.4e-68 227.7 2.5 8.3e-68 227.6 2.5 1.0 1 0 0 1 1 1 1 YfbU domain DUF412 PF04217.13 EHT99840.1 - 5.7e-60 201.3 0.2 6.4e-60 201.1 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF412 Acetate_kinase PF00871.17 EHT99841.1 - 9.1e-170 564.5 0.0 1e-169 564.3 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family Glucokinase PF02685.16 EHT99841.1 - 0.033 13.2 0.0 0.05 12.6 0.0 1.2 1 0 0 1 1 1 0 Glucokinase BcrAD_BadFG PF01869.20 EHT99841.1 - 0.072 12.6 0.0 0.17 11.3 0.0 1.5 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family PTA_PTB PF01515.19 EHT99842.1 - 2.4e-128 428.0 0.5 4.1e-128 427.2 0.5 1.4 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase AAA_26 PF13500.6 EHT99842.1 - 1.9e-52 178.0 0.0 4.2e-52 176.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain DRTGG PF07085.12 EHT99842.1 - 5.9e-31 106.4 0.0 2.2e-30 104.5 0.0 2.1 1 0 0 1 1 1 1 DRTGG domain LPD7 PF18821.1 EHT99842.1 - 0.0022 18.1 0.0 19 5.5 0.0 3.4 3 0 0 3 3 3 2 Large polyvalent protein-associated domain 7 ABC_tran PF00005.27 EHT99843.1 - 2.4e-33 115.6 0.0 3.8e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 EHT99843.1 - 1.6e-17 63.4 0.0 4.6e-17 62.0 0.0 1.8 1 0 0 1 1 1 1 TOBE domain SMC_N PF02463.19 EHT99843.1 - 0.0023 17.4 0.4 0.07 12.6 0.2 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 EHT99843.1 - 0.035 13.7 0.1 0.089 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 EHT99843.1 - 0.039 13.7 0.9 1.7 8.3 0.0 2.2 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EHT99843.1 - 0.041 14.1 0.1 0.13 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 EHT99843.1 - 0.062 12.3 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 EHT99843.1 - 0.095 13.1 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EHT99843.1 - 0.13 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 EHT99843.1 - 0.22 11.2 0.2 3.1 7.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Aminotran_1_2 PF00155.21 EHT99844.1 - 9.2e-26 90.9 0.0 1.4e-25 90.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 EHT99844.1 - 6.3e-15 54.6 0.3 2.9e-14 52.4 0.1 2.3 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family MarR_2 PF12802.7 EHT99844.1 - 0.0098 15.8 0.2 0.035 14.0 0.2 2.0 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 EHT99844.1 - 0.026 14.1 0.1 0.091 12.3 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 EHT99844.1 - 0.031 14.2 0.6 0.083 12.9 0.2 2.0 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Rrf2 PF02082.20 EHT99844.1 - 0.033 14.5 0.0 0.081 13.3 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator HTH_IclR PF09339.10 EHT99844.1 - 0.08 12.8 0.5 0.2 11.5 0.5 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain Fe_dep_repress PF01325.19 EHT99844.1 - 0.12 12.6 0.1 0.43 10.8 0.0 2.0 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain HTH_11 PF08279.12 EHT99844.1 - 0.17 11.9 0.5 0.6 10.1 0.1 2.1 2 0 0 2 2 2 0 HTH domain Aminotran_3 PF00202.21 EHT99845.1 - 5.1e-120 400.8 0.0 6.2e-120 400.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EHT99845.1 - 0.0043 16.3 0.0 0.11 11.7 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II BPD_transp_1 PF00528.22 EHT99846.1 - 1e-08 35.2 20.3 1e-08 35.2 20.3 2.1 3 0 0 3 3 3 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 EHT99847.1 - 7.9e-17 61.6 22.4 7.9e-17 61.6 22.4 2.3 1 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component NUDIX PF00293.28 EHT99848.1 - 1e-17 64.4 0.1 1.4e-17 64.0 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain YbjQ_1 PF01906.17 EHT99848.1 - 0.1 13.2 0.2 0.2 12.3 0.1 1.5 1 1 0 1 1 1 0 Putative heavy-metal-binding GST_C_4 PF14834.6 EHT99849.1 - 1.1e-50 170.9 0.4 1.5e-50 170.5 0.4 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EHT99849.1 - 2.1e-14 53.7 0.0 3.6e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EHT99849.1 - 3.2e-11 43.4 0.0 5.1e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EHT99849.1 - 1.3e-10 41.5 0.0 2.2e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EHT99849.1 - 0.15 12.1 1.2 0.42 10.7 0.2 1.9 1 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Epimerase PF01370.21 EHT99850.1 - 9.6e-20 71.1 0.0 2.7e-19 69.6 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1731 PF08338.11 EHT99850.1 - 7.3e-18 64.1 0.0 1.3e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) GDP_Man_Dehyd PF16363.5 EHT99850.1 - 1.4e-06 28.0 0.1 0.0027 17.1 0.0 3.0 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EHT99850.1 - 2e-05 24.6 0.0 3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EHT99850.1 - 0.0012 18.5 0.1 0.0016 18.0 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 EHT99850.1 - 0.0022 17.2 0.0 0.0034 16.5 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 EHT99850.1 - 0.045 12.8 0.1 0.062 12.3 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EHT99850.1 - 0.13 11.4 0.4 0.51 9.5 0.3 1.9 2 1 0 2 2 2 0 Male sterility protein MFS_1 PF07690.16 EHT99851.1 - 4e-31 108.2 86.9 7.7e-22 77.7 55.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF21 PF01595.20 EHT99851.1 - 0.0042 16.8 4.0 0.0042 16.8 4.0 2.8 3 1 1 4 4 4 1 Cyclin M transmembrane N-terminal domain FGGY_N PF00370.21 EHT99852.1 - 3.1e-80 269.3 0.1 4.2e-80 268.8 0.1 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EHT99852.1 - 9.6e-33 113.6 0.1 2e-32 112.5 0.1 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 EHT99852.1 - 0.0021 17.6 0.0 0.55 9.7 0.0 2.2 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Sugar-bind PF04198.13 EHT99853.1 - 6.3e-67 225.4 0.0 9.1e-67 224.9 0.0 1.2 1 0 0 1 1 1 1 Putative sugar-binding domain HTH_23 PF13384.6 EHT99853.1 - 2.5e-05 23.9 1.2 6.4e-05 22.6 0.3 2.1 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 EHT99853.1 - 2.7e-05 24.0 0.1 0.00011 22.0 0.1 2.1 2 0 0 2 2 2 1 MarR family Sigma70_r4 PF04545.16 EHT99853.1 - 0.00028 20.4 0.1 0.00064 19.2 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 EHT99853.1 - 0.00032 20.3 0.1 0.00084 19.0 0.1 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_Crp_2 PF13545.6 EHT99853.1 - 0.00043 20.2 0.0 0.001 19.0 0.0 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_3 PF01381.22 EHT99853.1 - 0.00056 19.9 0.2 0.0015 18.5 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix HTH_24 PF13412.6 EHT99853.1 - 0.0032 17.0 0.1 0.0066 16.0 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_31 PF13560.6 EHT99853.1 - 0.0099 16.2 1.3 0.024 15.0 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_11 PF08279.12 EHT99853.1 - 0.03 14.2 0.0 0.067 13.1 0.0 1.5 1 0 0 1 1 1 0 HTH domain HTH_28 PF13518.6 EHT99853.1 - 0.038 14.1 1.1 0.095 12.8 0.5 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT99853.1 - 0.044 13.8 0.1 0.093 12.8 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn helix Crp PF00325.20 EHT99853.1 - 0.052 13.2 1.2 0.098 12.3 0.2 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family HTH_38 PF13936.6 EHT99853.1 - 0.053 13.3 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain ABC_tran PF00005.27 EHT99854.1 - 2.5e-33 115.5 0.0 3.6e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EHT99854.1 - 2.9e-12 47.0 0.1 2.4e-06 27.6 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EHT99854.1 - 1.3e-07 31.3 0.8 1.1e-06 28.3 0.8 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EHT99854.1 - 0.00014 21.6 0.1 0.00025 20.7 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EHT99854.1 - 0.00014 21.7 0.0 0.012 15.3 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_13 PF13166.6 EHT99854.1 - 0.0018 17.1 0.0 0.13 10.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EHT99854.1 - 0.0036 17.7 0.0 0.0075 16.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.9 EHT99854.1 - 0.0051 15.7 0.0 0.54 9.0 0.0 2.3 2 0 0 2 2 2 1 Predicted ATPase of the ABC class PRK PF00485.18 EHT99854.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_23 PF13476.6 EHT99854.1 - 0.015 15.8 0.2 0.027 14.9 0.2 1.3 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 EHT99854.1 - 0.028 13.6 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_33 PF13671.6 EHT99854.1 - 0.036 14.2 0.1 0.07 13.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EHT99854.1 - 0.043 13.5 0.1 0.18 11.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 EHT99854.1 - 0.053 13.4 0.0 0.37 10.7 0.0 2.3 3 0 0 3 3 3 0 NACHT domain RsgA_GTPase PF03193.16 EHT99854.1 - 0.068 13.1 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase DUF87 PF01935.17 EHT99854.1 - 0.069 13.2 0.1 0.088 12.9 0.1 1.3 1 1 0 1 1 1 0 Helicase HerA, central domain AAA_22 PF13401.6 EHT99854.1 - 0.09 13.1 0.4 0.43 10.8 0.1 2.1 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EHT99854.1 - 0.11 11.9 0.0 0.3 10.4 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Dynamin_N PF00350.23 EHT99854.1 - 0.19 11.8 0.4 0.37 10.8 0.2 1.8 1 1 0 2 2 2 0 Dynamin family BPD_transp_1 PF00528.22 EHT99855.1 - 4.2e-14 52.7 13.8 4.2e-14 52.7 13.8 1.4 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Stevor PF17410.2 EHT99855.1 - 0.13 11.7 1.0 0.21 11.1 1.0 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame BPD_transp_1 PF00528.22 EHT99856.1 - 3.2e-23 82.4 13.3 4e-23 82.1 13.3 1.1 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component DcuC PF03606.15 EHT99856.1 - 0.29 9.5 9.0 0.24 9.8 2.2 2.0 2 0 0 2 2 2 0 C4-dicarboxylate anaerobic carrier SBP_bac_3 PF00497.20 EHT99857.1 - 2.8e-66 223.2 1.1 3.2e-66 223.0 1.1 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.11 EHT99857.1 - 7.4e-05 22.8 0.0 0.0037 17.2 0.0 2.1 1 1 1 2 2 2 1 NMT1/THI5 like Lig_chan-Glu_bd PF10613.9 EHT99857.1 - 0.00013 22.1 0.1 0.0049 17.0 0.1 2.3 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site YhfZ_C PF14503.6 EHT99857.1 - 0.07 12.7 0.0 0.25 10.8 0.0 1.8 1 1 1 2 2 2 0 YhfZ C-terminal domain Flavoprotein PF02441.19 EHT99858.1 - 2.1e-24 86.1 0.1 2.6e-24 85.7 0.1 1.1 1 0 0 1 1 1 1 Flavoprotein CTP_transf_like PF01467.26 EHT99858.1 - 0.045 14.0 0.1 0.22 11.7 0.1 1.9 2 0 0 2 2 2 0 Cytidylyltransferase-like Dak2 PF02734.17 EHT99858.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.4 1 1 0 1 1 1 0 DAK2 domain GATase_6 PF13522.6 EHT99859.1 - 2.4e-16 60.2 0.1 5.3e-16 59.0 0.1 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EHT99859.1 - 1.1e-14 54.3 0.0 2.2e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 EHT99859.1 - 1.4e-07 31.1 0.0 4.9e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 EHT99859.1 - 1.3e-05 24.3 0.0 9.4e-05 21.4 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferases class-II hnRNP_Q_AcD PF18360.1 EHT99859.1 - 0.1 12.6 0.0 0.34 10.9 0.0 2.0 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain Colicin_V PF02674.16 EHT99860.1 - 6.9e-38 129.9 13.3 8e-38 129.7 13.3 1.0 1 0 0 1 1 1 1 Colicin V production protein Arch_flagellin PF01917.16 EHT99860.1 - 0.14 12.4 0.9 0.24 11.6 0.9 1.4 1 0 0 1 1 1 0 Archaebacterial flagellin Rick_17kDa_Anti PF05433.15 EHT99860.1 - 0.48 10.3 2.9 0.79 9.6 2.9 1.3 1 0 0 1 1 1 0 Glycine zipper 2TM domain Phage_holin_4_1 PF05105.12 EHT99860.1 - 2.1 8.5 7.0 6.5 6.9 0.0 2.9 2 1 0 2 2 2 0 Bacteriophage holin family SPOR PF05036.13 EHT99861.1 - 1.9e-11 44.2 0.4 3e-11 43.5 0.4 1.3 1 0 0 1 1 1 1 Sporulation related domain RR_TM4-6 PF06459.12 EHT99861.1 - 3.9 7.2 8.7 4.6 7.0 8.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NARP1 PF12569.8 EHT99861.1 - 4.6 6.0 7.1 6.1 5.6 7.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Mur_ligase_M PF08245.12 EHT99862.1 - 1.8e-09 37.9 0.0 4e-09 36.7 0.0 1.6 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 EHT99862.1 - 1.7e-07 31.4 0.0 7.4e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Carboxyl_trans PF01039.22 EHT99863.1 - 9.3e-18 64.1 0.1 1.7e-17 63.3 0.1 1.4 1 1 0 1 1 1 1 Carboxyl transferase domain zf-ACC PF17848.1 EHT99863.1 - 8.7e-15 54.5 3.2 1.5e-14 53.7 3.2 1.4 1 0 0 1 1 1 1 Acetyl-coA carboxylase zinc finger domain zf-ribbon_3 PF13248.6 EHT99863.1 - 0.055 12.9 0.8 3.7 7.1 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 EHT99863.1 - 0.069 13.1 1.1 0.18 11.8 1.1 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.10 EHT99863.1 - 0.1 12.7 1.2 0.31 11.2 1.2 1.8 1 0 0 1 1 1 0 Zinc ribbon domain DZR PF12773.7 EHT99863.1 - 0.11 12.6 0.4 0.21 11.6 0.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon Tmemb_55A PF09788.9 EHT99863.1 - 0.13 11.4 0.4 0.24 10.4 0.4 1.4 1 0 0 1 1 1 0 Transmembrane protein 55A zf-FPG_IleRS PF06827.14 EHT99863.1 - 0.24 11.3 1.0 0.47 10.4 1.0 1.4 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS Auto_anti-p27 PF06677.12 EHT99863.1 - 0.7 10.1 4.1 0.27 11.4 0.8 2.0 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) SNARE_assoc PF09335.11 EHT99864.1 - 1.1e-23 84.0 4.7 1.1e-23 84.0 4.7 1.8 2 0 0 2 2 2 1 SNARE associated Golgi protein Doppel PF11466.8 EHT99864.1 - 0.29 10.8 1.6 12 5.7 0.1 3.0 3 0 0 3 3 3 0 Prion-like protein Doppel PseudoU_synth_1 PF01416.20 EHT99865.1 - 1.6e-39 134.7 0.1 1.7e-27 96.0 0.0 2.1 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF2344 PF10105.9 EHT99865.1 - 0.078 12.8 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) Semialdhyde_dhC PF02774.18 EHT99866.1 - 1.3e-30 106.8 0.1 3.7e-30 105.4 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 EHT99866.1 - 7.1e-24 84.6 0.0 1.6e-23 83.4 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 EHT99866.1 - 0.059 14.1 0.0 0.12 13.1 0.0 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Sacchrp_dh_NADP PF03435.18 EHT99866.1 - 0.13 12.6 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 EHT99866.1 - 0.15 11.6 0.0 0.65 9.5 0.0 1.9 2 0 0 2 2 2 0 NmrA-like family 2-Hacid_dh_C PF02826.19 EHT99867.1 - 6.6e-29 100.5 0.0 1e-28 99.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3410 PF11890.8 EHT99867.1 - 7.3e-29 99.4 0.0 1.2e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3410) 2-Hacid_dh PF00389.30 EHT99867.1 - 7.1e-19 67.8 0.0 1.1e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ThiF PF00899.21 EHT99867.1 - 0.15 11.4 0.1 0.25 10.7 0.1 1.3 1 0 0 1 1 1 0 ThiF family EamA PF00892.20 EHT99868.1 - 2.7e-39 134.4 43.2 1.2e-21 77.4 12.0 2.0 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EHT99868.1 - 0.002 17.5 11.3 0.057 12.8 5.5 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 EHT99868.1 - 0.0046 16.2 0.0 0.0046 16.2 0.0 1.6 2 0 0 2 2 2 1 Nucleotide-sugar transporter L6_membrane PF05805.12 EHT99868.1 - 0.055 13.0 0.6 0.055 13.0 0.6 2.8 1 1 3 4 4 4 0 L6 membrane protein Cytochrome-c551 PF10643.9 EHT99868.1 - 0.12 12.0 1.3 0.25 10.9 1.3 1.5 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Response_reg PF00072.24 EHT99869.1 - 1.8e-26 92.5 0.0 2.5e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 EHT99869.1 - 2.3e-17 62.8 0.1 7.8e-17 61.1 0.0 1.9 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal OKR_DC_1_N PF03709.15 EHT99869.1 - 0.0028 17.9 0.0 0.0046 17.2 0.0 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, N-terminal domain FleQ PF06490.11 EHT99869.1 - 0.0054 17.1 0.0 0.0085 16.5 0.0 1.4 1 1 0 1 1 1 1 Flagellar regulatory protein FleQ Adeno_VII PF03228.14 EHT99869.1 - 0.07 13.8 0.0 0.14 12.8 0.0 1.5 1 0 0 1 1 1 0 Adenoviral core protein VII Prim-Pol PF09250.11 EHT99869.1 - 0.11 12.8 0.5 0.71 10.2 0.1 2.0 1 1 1 2 2 2 0 Bifunctional DNA primase/polymerase, N-terminal GerE PF00196.19 EHT99869.1 - 0.17 11.4 0.1 6.2 6.5 0.2 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family TctB PF07331.11 EHT99870.1 - 1.6e-19 70.5 16.7 1.8e-19 70.3 16.7 1.0 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family MgtC PF02308.16 EHT99870.1 - 0.0059 17.0 2.2 0.015 15.7 2.1 1.7 1 1 0 1 1 1 1 MgtC family TctA PF01970.16 EHT99871.1 - 3.6e-142 473.9 47.3 4.6e-142 473.5 47.3 1.1 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctA family Stevor PF17410.2 EHT99871.1 - 0.12 11.9 0.2 0.12 11.9 0.2 2.2 3 0 0 3 3 3 0 Subtelomeric Variable Open Reading frame DUF3413 PF11893.8 EHT99871.1 - 0.45 9.7 6.4 1.7 7.8 6.4 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) DUF1018 PF06252.12 EHT99872.1 - 0.00082 20.4 4.5 0.0047 17.9 1.8 2.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1018) Rhodanese PF00581.20 EHT99873.1 - 5.4e-13 49.4 0.0 7.1e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Aminotran_1_2 PF00155.21 EHT99874.1 - 2.8e-23 82.7 0.0 4.6e-23 82.0 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 EHT99874.1 - 1.1e-15 57.0 0.1 3.4e-15 55.4 0.1 1.9 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 EHT99874.1 - 0.0062 16.5 0.1 0.0062 16.5 0.1 2.2 3 0 0 3 3 3 1 Crp-like helix-turn-helix domain LexA_DNA_bind PF01726.16 EHT99874.1 - 0.028 14.2 0.1 0.099 12.4 0.0 1.9 2 0 0 2 2 2 0 LexA DNA binding domain HTH_41 PF14502.6 EHT99874.1 - 0.035 13.8 0.0 0.035 13.8 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain GPP34 PF05719.11 EHT99874.1 - 0.14 12.2 3.9 0.32 11.0 0.9 2.4 2 1 0 2 2 2 0 Golgi phosphoprotein 3 (GPP34) Rrf2 PF02082.20 EHT99874.1 - 0.16 12.3 0.0 0.37 11.2 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator ketoacyl-synt PF00109.26 EHT99875.1 - 5.4e-40 137.6 1.8 8.8e-40 136.9 1.8 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EHT99875.1 - 5.5e-30 103.8 0.3 1.4e-29 102.5 0.3 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EHT99875.1 - 0.00056 19.4 0.1 0.0011 18.4 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 EHT99875.1 - 0.0029 18.1 0.0 0.0052 17.2 0.0 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_30 PF05430.11 EHT99876.1 - 6.8e-48 161.6 0.0 1.1e-47 160.9 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-methionine-dependent methyltransferase DAO PF01266.24 EHT99876.1 - 1.1e-46 160.1 3.5 1.7e-46 159.5 3.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EHT99876.1 - 0.00012 22.1 0.2 0.064 13.2 0.1 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EHT99876.1 - 0.00086 19.5 0.1 0.0049 17.1 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EHT99876.1 - 0.015 14.5 0.0 0.51 9.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 EHT99876.1 - 0.015 13.9 0.0 0.19 10.2 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Glyco_transf_4 PF13439.6 EHT99876.1 - 0.034 14.2 0.9 0.074 13.0 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase Family 4 ThiI PF02568.14 EHT99876.1 - 0.064 12.8 0.0 0.096 12.3 0.0 1.2 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) FAD_binding_3 PF01494.19 EHT99876.1 - 0.18 11.0 0.1 20 4.3 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain YfcL PF08891.11 EHT99877.1 - 8.6e-35 119.0 0.3 9.9e-35 118.8 0.3 1.0 1 0 0 1 1 1 1 YfcL protein EpmC PF04315.12 EHT99878.1 - 2.8e-80 267.7 0.1 3.2e-80 267.5 0.1 1.0 1 0 0 1 1 1 1 Elongation factor P hydroxylase TauE PF01925.19 EHT99879.1 - 8.2e-43 146.7 31.6 1e-42 146.4 31.6 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Peptidase_M74 PF03411.13 EHT99880.1 - 2.8e-95 318.4 0.0 3.3e-95 318.2 0.0 1.0 1 0 0 1 1 1 1 Penicillin-insensitive murein endopeptidase Chorismate_synt PF01264.21 EHT99881.1 - 8e-143 475.0 0.2 9.1e-143 474.9 0.2 1.0 1 0 0 1 1 1 1 Chorismate synthase Nfu_N PF08712.11 EHT99881.1 - 0.021 14.8 0.0 0.055 13.5 0.0 1.6 2 0 0 2 2 2 0 Scaffold protein Nfu/NifU N terminal MTS PF05175.14 EHT99882.1 - 5.2e-18 65.2 0.0 1.3e-16 60.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EHT99882.1 - 1.5e-10 41.0 0.0 2.2e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EHT99882.1 - 6.6e-10 39.6 0.0 1.4e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EHT99882.1 - 1.5e-06 27.9 0.0 2.1e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 EHT99882.1 - 5.6e-06 26.0 0.0 8.5e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 EHT99882.1 - 0.00017 21.3 0.0 0.00038 20.2 0.0 1.5 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_12 PF08242.12 EHT99882.1 - 0.00018 22.2 0.0 0.00059 20.5 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain UPF0020 PF01170.18 EHT99882.1 - 0.00021 21.1 0.8 0.00073 19.3 0.8 1.8 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.7 EHT99882.1 - 0.00021 21.3 0.0 0.00034 20.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EHT99882.1 - 0.00033 20.1 0.0 0.0005 19.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Met_10 PF02475.16 EHT99882.1 - 0.0016 18.3 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_2 PF00891.18 EHT99882.1 - 0.0017 17.7 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_11 PF08241.12 EHT99882.1 - 0.0018 18.9 0.0 0.0039 17.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EHT99882.1 - 0.018 14.5 0.0 0.064 12.7 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase CMAS PF02353.20 EHT99882.1 - 0.031 13.5 0.0 0.048 12.9 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EHT99882.1 - 0.036 13.9 0.0 0.082 12.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 EHT99882.1 - 0.049 13.4 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_24 PF13578.6 EHT99882.1 - 0.068 14.2 0.0 0.19 12.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 EHT99882.1 - 0.079 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase N6_Mtase PF02384.16 EHT99882.1 - 0.16 11.2 0.0 0.36 10.0 0.0 1.5 1 1 0 1 1 1 0 N-6 DNA Methylase PrmC_N PF17827.1 EHT99882.1 - 0.16 12.6 0.3 1.4 9.5 0.3 2.4 1 1 0 1 1 1 0 PrmC N-terminal domain AviRa PF11599.8 EHT99882.1 - 0.28 10.6 0.3 0.73 9.2 0.1 1.7 1 1 1 2 2 2 0 RRNA methyltransferase AviRa Smr PF01713.21 EHT99883.1 - 1.8e-17 63.5 0.0 2.8e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Smr domain MCPsignal PF00015.21 EHT99884.1 - 1.1e-53 181.6 18.7 1.1e-53 181.6 18.7 3.9 3 1 1 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 EHT99884.1 - 5.6e-12 45.8 1.0 5.6e-12 45.8 1.0 4.1 4 0 0 4 4 4 1 HAMP domain HBM PF16591.5 EHT99884.1 - 2.9e-09 36.7 16.2 2.9e-09 36.7 16.2 3.3 3 0 0 3 3 3 1 Helical bimodular sensor domain 4HB_MCP_1 PF12729.7 EHT99884.1 - 1e-06 28.5 5.4 1e-06 28.5 5.4 5.6 5 2 0 6 6 6 1 Four helix bundle sensory module for signal transduction HAP1_N PF04849.13 EHT99884.1 - 0.0019 17.4 5.2 0.039 13.2 0.2 2.7 1 1 1 2 2 2 2 HAP1 N-terminal conserved region STATa_Ig PF18214.1 EHT99884.1 - 0.018 15.1 0.2 0.072 13.1 0.2 2.0 1 0 0 1 1 1 0 STATa Immunoglobulin-like domain DUF4064 PF13273.6 EHT99884.1 - 0.026 14.8 5.8 0.48 10.7 1.8 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF5383 PF17355.2 EHT99884.1 - 0.28 11.5 2.8 0.47 10.8 0.1 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5383) PSD2 PF07624.11 EHT99884.1 - 2.1 8.2 5.9 1.5 8.7 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1585) His_Phos_1 PF00300.22 EHT99885.1 - 6.9e-08 32.4 0.0 3.8e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) 3HCDH_N PF02737.18 EHT99886.1 - 1e-57 194.9 0.0 2e-57 194.0 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 EHT99886.1 - 4.3e-38 131.1 0.0 7.5e-38 130.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 EHT99886.1 - 1.3e-33 115.4 0.0 1.1e-25 90.0 0.0 2.8 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 EHT99886.1 - 1.5e-25 90.4 0.0 1.5e-25 90.4 0.0 1.6 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Thiolase_C PF02803.18 EHT99887.1 - 6.1e-36 122.8 0.9 9.7e-35 118.9 0.9 2.2 1 1 0 1 1 1 1 Thiolase, C-terminal domain Thiolase_N PF00108.23 EHT99887.1 - 1.5e-33 116.3 0.1 2.1e-33 115.8 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_N PF00108.23 EHT99888.1 - 1.4e-18 67.2 0.6 1.7e-18 67.0 0.6 1.0 1 0 0 1 1 1 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.26 EHT99888.1 - 0.0064 16.1 0.4 0.0092 15.6 0.4 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain DUF406 PF04175.12 EHT99889.1 - 3.1e-36 123.7 0.6 3.5e-36 123.6 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF406) Toluene_X PF03349.16 EHT99890.1 - 5.6e-139 463.4 13.8 6.5e-139 463.2 13.8 1.0 1 0 0 1 1 1 1 Outer membrane protein transport protein (OMPP1/FadL/TodX) OMP_b-brl PF13505.6 EHT99890.1 - 0.00039 20.6 29.9 0.019 15.1 15.2 2.8 2 2 0 2 2 2 2 Outer membrane protein beta-barrel domain DUF2490 PF10677.9 EHT99890.1 - 0.003 17.5 4.8 2.5 8.0 0.0 4.2 3 2 1 4 4 4 1 Protein of unknown function (DUF2490) YadA_anchor PF03895.15 EHT99890.1 - 0.53 10.4 17.1 1.7 8.8 1.7 5.2 5 2 0 5 5 5 0 YadA-like membrane anchor domain MlaA PF04333.13 EHT99891.1 - 3.2e-64 216.2 0.1 3.7e-64 216.0 0.1 1.0 1 0 0 1 1 1 1 MlaA lipoprotein TPR_19 PF14559.6 EHT99892.1 - 1.5e-07 31.8 10.5 0.0044 17.5 0.7 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EHT99892.1 - 4.7e-07 29.4 3.4 0.011 15.8 1.5 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EHT99892.1 - 2.1e-05 25.0 11.6 0.02 15.7 0.9 4.3 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EHT99892.1 - 0.00086 19.3 0.2 0.1 12.9 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EHT99892.1 - 0.00089 19.0 0.5 1.5 8.8 0.4 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EHT99892.1 - 0.0061 17.2 9.6 0.047 14.3 6.2 2.7 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EHT99892.1 - 0.0062 17.1 2.8 0.67 10.7 0.6 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EHT99892.1 - 0.0079 16.5 4.0 0.34 11.4 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EHT99892.1 - 0.016 15.4 1.3 0.039 14.2 1.3 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EHT99892.1 - 0.018 15.2 7.6 0.056 13.6 0.1 2.8 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 EHT99892.1 - 0.13 13.0 3.5 12 6.8 2.6 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat CcmH PF03918.14 EHT99893.1 - 2.7e-54 182.3 0.1 3.3e-54 182.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome C biogenesis protein DUF3797 PF12677.7 EHT99893.1 - 0.028 14.3 0.0 0.074 12.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) CpXC PF14353.6 EHT99893.1 - 0.029 14.4 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 CpXC protein UPF0220 PF05255.11 EHT99893.1 - 0.19 11.3 0.6 0.32 10.5 0.6 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0220) Redoxin PF08534.10 EHT99894.1 - 3.4e-24 85.2 0.0 4.3e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EHT99894.1 - 1.1e-14 54.4 0.0 1.3e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 EHT99894.1 - 1.4e-05 25.5 0.0 2.3e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EHT99894.1 - 0.00015 22.0 0.0 0.00024 21.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 EHT99894.1 - 0.0014 18.5 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 EHT99894.1 - 0.015 15.5 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like CcmF_C PF16327.5 EHT99895.1 - 1.6e-129 431.9 8.2 1.6e-129 431.9 8.2 2.8 3 1 0 3 3 3 1 Cytochrome c-type biogenesis protein CcmF C-terminal Cytochrom_C_asm PF01578.20 EHT99895.1 - 1.5e-54 185.0 20.1 1.5e-54 185.0 20.1 3.2 3 1 1 4 4 4 1 Cytochrome C assembly protein UPF0542 PF15086.6 EHT99895.1 - 0.075 13.0 1.4 0.31 11.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 DUF2339 PF10101.9 EHT99895.1 - 0.12 10.9 67.7 0.12 10.9 20.2 3.0 1 1 1 3 3 3 0 Predicted membrane protein (DUF2339) CcmE PF03100.15 EHT99896.1 - 1.7e-41 141.2 0.0 2e-41 141.0 0.0 1.0 1 0 0 1 1 1 1 CcmE CcmD PF04995.14 EHT99897.1 - 1.3e-17 63.5 2.4 2e-17 63.0 2.4 1.3 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) ResB PF05140.14 EHT99897.1 - 0.0078 15.0 0.4 0.0085 14.9 0.4 1.0 1 0 0 1 1 1 1 ResB-like family Cytochrom_C_asm PF01578.20 EHT99898.1 - 9.8e-32 110.5 18.8 9.8e-32 110.5 18.8 1.5 2 0 0 2 2 2 1 Cytochrome C assembly protein CcmB PF03379.13 EHT99899.1 - 2.4e-90 301.7 23.0 2.8e-90 301.6 23.0 1.0 1 0 0 1 1 1 1 CcmB protein ABC2_membrane PF01061.24 EHT99899.1 - 1e-05 25.1 4.4 1e-05 25.1 4.4 1.6 1 1 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_2 PF12679.7 EHT99899.1 - 0.19 11.0 14.4 0.41 9.9 14.4 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 EHT99899.1 - 0.96 9.4 6.3 0.73 9.8 3.6 2.2 1 1 1 2 2 2 0 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 EHT99899.1 - 1.8 7.6 17.3 0.87 8.6 13.4 2.2 1 1 1 2 2 2 0 ABC-2 family transporter protein ABC_tran PF00005.27 EHT99900.1 - 1.8e-27 96.6 0.0 2.3e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EHT99900.1 - 7.9e-12 45.6 0.0 3.4e-05 23.8 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EHT99900.1 - 1.7e-05 24.4 0.0 0.02 14.3 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 EHT99900.1 - 0.0024 17.6 0.3 0.024 14.3 0.3 2.5 1 1 0 1 1 1 1 AAA domain DUF3584 PF12128.8 EHT99900.1 - 0.0043 14.6 0.0 0.0058 14.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_23 PF13476.6 EHT99900.1 - 0.0066 17.0 0.0 0.0092 16.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EHT99900.1 - 0.013 15.9 0.1 0.019 15.4 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EHT99900.1 - 0.019 14.7 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_27 PF13514.6 EHT99900.1 - 0.025 14.2 0.1 0.38 10.3 0.0 2.5 2 1 1 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 EHT99900.1 - 0.028 14.3 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 EHT99900.1 - 0.038 14.6 0.0 0.29 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 EHT99900.1 - 0.056 12.1 0.0 0.059 12.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_35 PF14516.6 EHT99900.1 - 0.065 12.1 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain TsaE PF02367.17 EHT99900.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Form_Nir_trans PF01226.17 EHT99901.1 - 5.5e-39 133.9 15.9 6.4e-39 133.7 15.9 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter rve PF00665.26 EHT99902.1 - 7.9e-24 84.1 0.0 1.9e-23 82.9 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 EHT99902.1 - 4.2e-22 77.7 0.2 1.5e-21 75.9 0.2 2.0 1 1 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 EHT99902.1 - 4.6e-13 49.1 6.6 8.3e-13 48.3 6.6 1.4 1 0 0 1 1 1 1 HTH-like domain HTH_32 PF13565.6 EHT99902.1 - 0.062 13.9 1.1 0.062 13.9 1.1 2.5 3 0 0 3 3 3 0 Homeodomain-like domain DDE_Tnp_IS240 PF13610.6 EHT99902.1 - 0.096 12.9 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 DDE domain DDE_Tnp_IS66 PF03050.14 EHT99903.1 - 8.6e-98 327.3 4.1 3.2e-97 325.4 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHT99903.1 - 3.1e-16 59.3 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHT99903.1 - 8.1e-15 54.9 1.3 1.9e-14 53.8 1.3 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHT99903.1 - 1.7e-11 44.8 9.6 3.5e-11 43.7 9.6 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHT99903.1 - 0.017 14.9 6.4 0.027 14.3 6.4 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Phage_HK97_TLTM PF06120.11 EHT99903.1 - 0.022 14.0 1.7 0.042 13.0 1.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHT99903.1 - 0.022 15.1 4.3 0.091 13.1 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Exonuc_VII_L PF02601.15 EHT99903.1 - 0.029 14.0 1.8 0.039 13.5 0.6 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit FUSC PF04632.12 EHT99903.1 - 0.036 12.6 6.9 0.056 12.0 6.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tho2 PF11262.8 EHT99903.1 - 0.057 12.6 0.5 0.094 11.9 0.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Troponin PF00992.20 EHT99903.1 - 0.062 13.6 3.0 0.11 12.8 3.0 1.3 1 0 0 1 1 1 0 Troponin LXG PF04740.12 EHT99903.1 - 0.11 12.2 2.6 0.33 10.6 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHT99903.1 - 0.16 11.8 10.8 0.26 11.1 10.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family UME PF08064.13 EHT99903.1 - 0.16 11.9 0.5 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain HalX PF08663.10 EHT99903.1 - 0.23 11.8 3.1 0.59 10.5 3.1 1.7 1 0 0 1 1 1 0 HalX domain DHR10 PF18595.1 EHT99903.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF1192 PF06698.11 EHT99903.1 - 0.47 10.5 5.3 3.4 7.8 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHT99903.1 - 1.1 8.4 3.1 1.7 7.8 3.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHT99903.1 - 2.8 7.4 7.9 6.1 6.3 7.9 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHT99903.1 - 3.3 8.1 7.9 6.7 7.0 7.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 EHT99903.1 - 7.2 7.3 8.7 7.7 7.2 1.0 3.0 1 1 1 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHT99904.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHT99905.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHT99905.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHT99905.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHT99905.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix Phage_spike PF18715.1 EHT99906.1 - 0.00035 20.6 1.0 0.00054 20.0 1.0 1.3 1 0 0 1 1 1 1 Phage spike trimer Sigma_reg_N PF13800.6 EHT99906.1 - 0.12 12.7 0.1 9.4 6.6 0.0 2.1 1 1 1 2 2 2 0 Sigma factor regulator N-terminal DDE_3 PF13358.6 EHT99907.1 - 1.5e-22 80.0 0.0 2.4e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 EHT99907.1 - 2.3e-10 40.0 1.5 4.2e-09 35.9 0.1 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 EHT99907.1 - 5.8e-09 36.4 1.1 3.4e-08 34.0 0.3 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 EHT99907.1 - 5.1e-07 29.6 1.2 1.3e-06 28.4 0.3 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_33 PF13592.6 EHT99907.1 - 1.7e-06 27.5 3.9 5.2e-06 26.0 0.3 2.9 3 0 0 3 3 3 1 Winged helix-turn helix HTH_28 PF13518.6 EHT99907.1 - 1.9e-05 24.7 0.3 0.00024 21.2 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHT99907.1 - 0.038 14.5 0.2 0.073 13.6 0.2 1.4 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 HTH_38 PF13936.6 EHT99907.1 - 0.061 13.1 0.6 0.18 11.6 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain DUF333 PF03891.15 EHT99908.1 - 3.5e-24 84.7 0.0 4.3e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF333) LPAM_1 PF08139.12 EHT99908.1 - 0.0037 17.7 3.6 0.0055 17.1 3.6 1.2 1 0 0 1 1 1 1 Prokaryotic membrane lipoprotein lipid attachment site Involucrin_N PF10583.9 EHT99908.1 - 0.073 13.7 0.0 0.097 13.3 0.0 1.2 1 0 0 1 1 1 0 Involucrin of squamous epithelia N-terminus LPAM_2 PF13627.6 EHT99908.1 - 2.1 8.3 6.6 3 7.8 6.6 1.3 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site Caudo_TAP PF02413.17 EHT99909.1 - 1e-10 41.9 0.0 1.6e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Caudovirales tail fibre assembly protein, lambda gpK Collar PF07484.12 EHT99910.1 - 3.5e-09 36.5 0.2 3.5e-09 36.5 0.2 1.9 2 0 0 2 2 2 1 Phage Tail Collar Domain DUF2612 PF11041.8 EHT99911.1 - 3.5e-31 108.5 0.0 4e-31 108.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2612) Gp138_N PF18352.1 EHT99914.1 - 1.2e-31 108.6 0.0 2.4e-31 107.7 0.0 1.5 1 0 0 1 1 1 1 Phage protein Gp138 N-terminal domain 4HBT PF03061.22 EHT99914.1 - 0.012 16.0 0.0 0.026 14.9 0.0 1.6 1 0 0 1 1 1 0 Thioesterase superfamily Big_9 PF17963.1 EHT99914.1 - 1 10.2 5.6 0.93 10.3 2.9 2.1 2 0 0 2 2 2 0 Bacterial Ig domain Phage_spike PF18715.1 EHT99914.1 - 4.4 7.5 10.6 13 6.0 6.1 3.1 2 1 1 3 3 3 0 Phage spike trimer RL11D PF11088.8 EHT99916.1 - 0.016 15.5 0.0 0.024 14.9 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 SecY PF00344.20 EHT99918.1 - 0.0039 16.5 0.2 0.0054 16.0 0.2 1.2 1 0 0 1 1 1 1 SecY translocase HTH_3 PF01381.22 EHT99920.1 - 2.3e-08 34.0 0.2 6.3e-08 32.6 0.0 1.8 2 1 0 2 2 2 1 Helix-turn-helix HTH_31 PF13560.6 EHT99920.1 - 2.9e-05 24.3 0.4 5.6e-05 23.4 0.5 1.6 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_7 PF02796.15 EHT99920.1 - 0.0009 19.3 0.0 0.0016 18.4 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_19 PF12844.7 EHT99920.1 - 0.0034 17.4 0.0 0.008 16.2 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain TetR_N PF00440.23 EHT99920.1 - 0.0043 16.8 0.1 0.012 15.4 0.1 1.8 1 1 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_26 PF13443.6 EHT99920.1 - 0.0065 16.9 0.0 0.0098 16.3 0.0 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_8 PF02954.19 EHT99920.1 - 0.008 15.9 0.6 0.082 12.7 0.4 2.3 1 1 1 2 2 2 1 Bacterial regulatory protein, Fis family HTH_1 PF00126.27 EHT99920.1 - 0.024 14.6 0.1 0.033 14.1 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family LZ_Tnp_IS481 PF13011.6 EHT99920.1 - 0.041 14.4 0.0 0.053 14.1 0.0 1.3 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 HTH_28 PF13518.6 EHT99920.1 - 0.049 13.8 0.4 0.098 12.8 0.3 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 EHT99920.1 - 0.063 13.3 0.3 1.6 8.7 0.1 2.3 2 1 0 2 2 2 0 Crp-like helix-turn-helix domain LacI PF00356.21 EHT99920.1 - 0.11 12.4 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family HTH_23 PF13384.6 EHT99920.1 - 0.12 12.2 0.1 0.3 10.9 0.1 1.7 1 1 0 1 1 1 0 Homeodomain-like domain HTH_3 PF01381.22 EHT99921.1 - 1.7e-11 44.0 0.1 2.3e-11 43.6 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EHT99921.1 - 7.9e-08 32.5 0.2 1.1e-07 32.1 0.2 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 EHT99921.1 - 1.4e-06 27.9 0.1 2.9e-06 26.9 0.0 1.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_19 PF12844.7 EHT99921.1 - 2.7e-06 27.3 0.0 3.7e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain LacI PF00356.21 EHT99921.1 - 5e-05 23.0 0.1 7e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family HTH_28 PF13518.6 EHT99921.1 - 0.00021 21.3 0.0 0.00037 20.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 EHT99921.1 - 0.00043 20.2 0.1 0.00077 19.4 0.0 1.5 1 1 0 1 1 1 1 Winged helix-turn helix HTH_7 PF02796.15 EHT99921.1 - 0.0008 19.4 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase YdaS_antitoxin PF15943.5 EHT99921.1 - 0.0019 18.0 0.0 0.0031 17.3 0.0 1.3 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT MarR PF01047.22 EHT99921.1 - 0.0037 17.2 0.0 0.1 12.5 0.0 2.2 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.7 EHT99921.1 - 0.0041 17.0 0.1 0.0095 15.8 0.0 1.6 2 0 0 2 2 2 1 MarR family HTH_8 PF02954.19 EHT99921.1 - 0.0053 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family CENP-B_N PF04218.13 EHT99921.1 - 0.0096 15.5 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Crp_2 PF13545.6 EHT99921.1 - 0.0098 15.9 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_1 PF00126.27 EHT99921.1 - 0.01 15.8 0.0 0.028 14.4 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_37 PF13744.6 EHT99921.1 - 0.014 15.3 0.1 0.045 13.7 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_30 PF13556.6 EHT99921.1 - 0.024 14.4 0.0 0.081 12.7 0.0 1.8 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_IclR PF09339.10 EHT99921.1 - 0.028 14.2 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain Sigma70_ECF PF07638.11 EHT99921.1 - 0.03 14.2 0.1 0.066 13.1 0.0 1.6 1 1 1 2 2 2 0 ECF sigma factor HTH_26 PF13443.6 EHT99921.1 - 0.032 14.7 0.0 0.083 13.3 0.0 1.7 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain RWP-RK PF02042.15 EHT99921.1 - 0.032 14.2 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 RWP-RK domain DUF134 PF02001.16 EHT99921.1 - 0.036 14.6 0.0 0.047 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF134 HTH_psq PF05225.16 EHT99921.1 - 0.05 13.4 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Sigma70_r4 PF04545.16 EHT99921.1 - 0.084 12.4 0.1 0.24 11.0 0.0 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_38 PF13936.6 EHT99921.1 - 0.087 12.6 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_17 PF12728.7 EHT99921.1 - 0.12 12.6 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain TnsD PF15978.5 EHT99921.1 - 0.18 10.7 0.0 0.19 10.7 0.0 1.0 1 0 0 1 1 1 0 Tn7-like transposition protein D DUF485 PF04341.12 EHT99922.1 - 0.025 14.5 0.8 0.027 14.4 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF485 Phage_TAC_9 PF10876.8 EHT99923.1 - 3e-19 69.4 0.0 3.9e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 Phage tail assemb.y chaperone protein, TAC CcmE PF03100.15 EHT99923.1 - 0.01 15.8 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 CcmE DUF3277 PF11681.8 EHT99924.1 - 1e-05 25.5 0.0 1.2e-05 25.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3277) S8_pro-domain PF16470.5 EHT99924.1 - 0.014 16.2 0.0 0.02 15.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase S8 pro-domain DUF3383 PF11863.8 EHT99925.1 - 6.8e-68 229.8 1.3 1.3e-60 205.8 0.1 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3383) DDE_Tnp_1 PF01609.21 EHT99930.1 - 5.5e-20 71.9 0.0 1e-19 71.0 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain ICL PF00463.21 EHT99932.1 - 0.022 13.3 0.6 0.031 12.8 0.6 1.1 1 0 0 1 1 1 0 Isocitrate lyase family FKBP_N PF01346.18 EHT99932.1 - 0.066 14.2 0.6 0.13 13.2 0.6 1.5 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase HTH_29 PF13551.6 EHT99932.1 - 0.092 12.8 0.3 0.3 11.1 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn helix DUF760 PF05542.11 EHT99932.1 - 0.15 12.4 0.0 0.41 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF760) Phage_Mu_F PF04233.14 EHT99933.1 - 0.0035 18.1 0.1 0.0059 17.3 0.1 1.4 1 0 0 1 1 1 1 Phage Mu protein F like protein DUF4055 PF13264.6 EHT99934.1 - 6.2e-43 146.2 0.3 1e-42 145.5 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4055) Terminase_6 PF03237.15 EHT99935.1 - 1.2e-33 116.6 0.0 1.6e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 Terminase-like family Terminase_6C PF17289.2 EHT99935.1 - 8.5e-07 29.2 0.0 1.7e-06 28.2 0.0 1.5 1 1 0 1 1 1 1 Terminase RNaseH-like domain DDE_3 PF13358.6 EHT99936.1 - 1e-22 80.5 0.1 2.8e-22 79.0 0.0 1.7 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_23 PF13384.6 EHT99936.1 - 2.8e-10 39.7 1.5 4.7e-09 35.8 0.1 3.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 EHT99936.1 - 6.2e-09 36.4 1.1 3.8e-08 33.8 0.3 2.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 EHT99936.1 - 5.8e-07 29.4 1.2 1.4e-06 28.2 0.3 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_33 PF13592.6 EHT99936.1 - 2.4e-06 27.1 4.0 5.8e-06 25.9 0.3 2.9 3 0 0 3 3 3 1 Winged helix-turn helix HTH_28 PF13518.6 EHT99936.1 - 2.1e-05 24.6 0.3 0.00027 21.0 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHT99936.1 - 0.04 14.4 0.1 0.083 13.4 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 HTH_38 PF13936.6 EHT99936.1 - 0.068 12.9 0.6 0.2 11.5 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain Terminase_2 PF03592.16 EHT99937.1 - 2.7e-27 96.0 0.9 3.5e-27 95.6 0.2 1.6 2 0 0 2 2 2 1 Terminase small subunit Cytochrom_C PF00034.21 EHT99937.1 - 0.058 14.5 0.6 0.19 12.9 0.1 2.0 1 1 1 2 2 2 0 Cytochrome c PDR_assoc PF08370.11 EHT99938.1 - 0.14 12.0 0.1 2.5 7.9 0.1 2.3 2 0 0 2 2 2 0 Plant PDR ABC transporter associated MAF_flag10 PF01973.18 EHT99940.1 - 3.8e-06 26.7 0.1 0.00029 20.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function DUF115 DUF826 PF05696.11 EHT99941.1 - 5.1e-21 74.5 3.4 5.9e-21 74.3 3.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF826) DUF2778 PF10908.8 EHT99942.1 - 5.6e-06 26.6 0.0 5.6e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2778) YkuD PF03734.14 EHT99942.1 - 0.088 13.2 0.1 0.095 13.1 0.1 1.1 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain Phage_lysis PF03245.13 EHT99943.1 - 1.4e-22 80.1 5.0 1.9e-22 79.7 5.0 1.1 1 0 0 1 1 1 1 Bacteriophage Rz lysis protein LPAM_1 PF08139.12 EHT99943.1 - 0.017 15.6 0.2 0.032 14.7 0.2 1.5 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Fib_alpha PF08702.10 EHT99943.1 - 0.67 10.1 4.1 9.8 6.4 4.1 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 EHT99943.1 - 2.7 8.5 5.2 5.3 7.6 0.6 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Glyco_hydro_19 PF00182.19 EHT99944.1 - 7e-08 32.6 1.8 1e-06 28.8 0.7 2.7 1 1 1 2 2 2 1 Chitinase class I Collagen_bind_2 PF12904.7 EHT99944.1 - 0.083 12.9 0.0 1 9.4 0.0 2.3 2 0 0 2 2 2 0 Putative collagen-binding domain of a collagenase Phage_holin_3_1 PF05106.12 EHT99945.1 - 7e-05 23.2 0.1 7.5e-05 23.1 0.1 1.0 1 0 0 1 1 1 1 Phage holin family (Lysis protein S) Phage_integrase PF00589.22 EHT99946.1 - 9.4e-14 51.6 0.0 1.7e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family Arm-DNA-bind_3 PF13356.6 EHT99946.1 - 2.3e-13 50.3 0.1 4.3e-13 49.4 0.1 1.4 1 0 0 1 1 1 1 Arm DNA-binding domain Phage_int_SAM_3 PF14659.6 EHT99946.1 - 2.6e-05 24.4 0.7 9.3e-05 22.6 0.1 2.2 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_integrase PF00589.22 EHT99947.1 - 1.8e-32 112.5 0.0 2.8e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Arm-DNA-bind_3 PF13356.6 EHT99947.1 - 3.2e-19 69.1 0.2 7.4e-19 67.9 0.2 1.6 1 0 0 1 1 1 1 Arm DNA-binding domain Phage_int_SAM_3 PF14659.6 EHT99947.1 - 1.4e-05 25.2 0.0 2.7e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Caudo_TAP PF02413.17 EHT99948.1 - 1e-22 80.7 2.3 1.1e-22 80.6 2.3 1.0 1 0 0 1 1 1 1 Caudovirales tail fibre assembly protein, lambda gpK Collar PF07484.12 EHT99949.1 - 0.017 15.2 0.0 0.042 13.9 0.0 1.7 1 0 0 1 1 1 0 Phage Tail Collar Domain DUF2612 PF11041.8 EHT99950.1 - 1.4e-50 171.7 0.4 1.1e-47 162.3 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF2612) Baseplate_J PF04865.14 EHT99951.1 - 2.6e-13 49.7 8.2 4.9e-13 48.8 8.2 1.4 1 0 0 1 1 1 1 Baseplate J-like protein Lumazine_bd_2 PF12893.7 EHT99951.1 - 0.19 12.4 0.0 3.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Putative lumazine-binding Gp138_N PF18352.1 EHT99953.1 - 9.4e-42 141.1 0.4 5.3e-41 138.7 0.1 2.3 2 0 0 2 2 2 1 Phage protein Gp138 N-terminal domain DUF3236 PF11576.8 EHT99956.1 - 0.076 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) SLT PF01464.20 EHT99957.1 - 1e-23 83.2 0.1 2.7e-23 81.8 0.1 1.8 1 0 0 1 1 1 1 Transglycosylase SLT domain PhageMin_Tail PF10145.9 EHT99957.1 - 6.8e-05 22.8 3.8 6.8e-05 22.8 3.8 3.6 2 1 1 3 3 3 1 Phage-related minor tail protein Transglycosylas PF06737.14 EHT99957.1 - 0.014 16.0 0.1 0.039 14.6 0.1 1.8 1 0 0 1 1 1 0 Transglycosylase-like domain Pho86 PF11124.8 EHT99957.1 - 0.015 14.8 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 Lysozyme_like PF13702.6 EHT99957.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Lysozyme-like DUF3277 PF11681.8 EHT99959.1 - 3.3e-69 231.3 2.4 3.6e-69 231.2 2.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3277) DUF3383 PF11863.8 EHT99960.1 - 5.2e-125 418.2 15.0 6e-100 335.5 13.2 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3383) ALF PF03752.13 EHT99963.1 - 0.45 10.5 8.4 0.19 11.7 3.8 2.4 1 1 1 2 2 2 0 Short repeats of unknown function DUF4054 PF13262.6 EHT99964.1 - 5.6e-32 110.0 0.0 6.4e-32 109.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4054) FAM76 PF16046.5 EHT99965.1 - 2.8e-05 23.7 0.6 2.8e-05 23.7 0.6 1.1 1 0 0 1 1 1 1 FAM76 protein RasGAP_C PF03836.15 EHT99965.1 - 0.001 19.2 3.1 0.0015 18.7 3.1 1.2 1 0 0 1 1 1 1 RasGAP C-terminus CR6_interact PF10147.9 EHT99965.1 - 0.0013 18.5 0.2 0.0015 18.3 0.2 1.0 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF5082 PF16888.5 EHT99965.1 - 0.0023 18.2 2.9 0.0032 17.7 2.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) MPS2 PF17060.5 EHT99965.1 - 0.0036 16.6 0.1 0.0036 16.6 0.1 1.0 1 0 0 1 1 1 1 Monopolar spindle protein 2 UPF0242 PF06785.11 EHT99965.1 - 0.0047 17.1 2.4 0.0052 16.9 2.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus ASD2 PF08687.11 EHT99965.1 - 0.0049 16.5 0.8 0.0053 16.4 0.8 1.1 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 Sec2p PF06428.11 EHT99965.1 - 0.0069 16.3 1.5 0.01 15.8 1.5 1.4 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p DUF2680 PF10925.8 EHT99965.1 - 0.018 15.1 0.5 0.018 15.1 0.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2680) KASH_CCD PF14662.6 EHT99965.1 - 0.02 14.7 3.0 0.15 11.9 3.0 1.9 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH SlyX PF04102.12 EHT99965.1 - 0.02 15.5 4.4 0.036 14.7 4.2 1.6 1 1 0 1 1 1 0 SlyX Spc7 PF08317.11 EHT99965.1 - 0.023 13.6 1.4 0.026 13.4 1.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 EHT99965.1 - 0.027 14.6 2.3 0.036 14.2 2.3 1.2 1 0 0 1 1 1 0 Tropomyosin like TraF_2 PF13729.6 EHT99965.1 - 0.029 13.7 2.3 0.037 13.4 2.3 1.1 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein DivIVA PF05103.13 EHT99965.1 - 0.031 14.4 1.8 0.046 13.8 1.8 1.3 1 0 0 1 1 1 0 DivIVA protein DivIC PF04977.15 EHT99965.1 - 0.043 13.6 7.6 0.083 12.7 5.0 2.1 1 1 1 2 2 2 0 Septum formation initiator HSBP1 PF06825.12 EHT99965.1 - 0.072 13.0 2.4 0.076 12.9 0.6 1.9 2 0 0 2 2 2 0 Heat shock factor binding protein 1 DUF4407 PF14362.6 EHT99965.1 - 0.081 12.3 2.2 0.12 11.7 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BBP1_C PF15272.6 EHT99965.1 - 0.12 12.1 3.1 0.16 11.8 3.1 1.1 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal HTH_Tnp_1 PF01527.20 EHT99965.1 - 0.13 12.6 0.2 7.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Transposase FlxA PF14282.6 EHT99965.1 - 1.4 9.0 12.8 4 7.5 12.8 1.7 1 1 0 1 1 1 0 FlxA-like protein DUF2184 PF09950.9 EHT99966.1 - 2.8e-80 269.4 0.1 3.5e-80 269.0 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2184) DUF2213 PF09979.9 EHT99968.1 - 5.7e-47 159.8 0.0 9.1e-47 159.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2213) DUF2277 PF10041.9 EHT99968.1 - 0.11 12.9 0.2 0.46 10.9 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2277) Phage_Mu_F PF04233.14 EHT99969.1 - 1.6e-16 61.0 0.0 3.2e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Phage Mu protein F like protein DUF1073 PF06381.11 EHT99970.1 - 3.1e-112 374.9 0.0 4e-112 374.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1073) DUF2280 PF10045.9 EHT99972.1 - 4.7e-49 164.9 0.2 6.7e-49 164.4 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2280) Ribosomal_L9_C PF03948.14 EHT99972.1 - 0.049 14.1 0.2 0.17 12.4 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein L9, C-terminal domain DUF2570 PF10828.8 EHT99976.1 - 0.059 13.2 1.3 0.081 12.8 1.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) Glyco_hydro_19 PF00182.19 EHT99977.1 - 2.1e-07 31.1 0.2 7.4e-06 26.0 0.1 2.5 1 1 1 2 2 2 1 Chitinase class I Methyltransf_23 PF13489.6 EHT99978.1 - 9e-07 28.9 0.0 1.4e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RusA PF05866.11 EHT99981.1 - 9.3e-11 42.4 0.7 1.1e-10 42.1 0.7 1.1 1 0 0 1 1 1 1 Endodeoxyribonuclease RusA DUF1364 PF07102.12 EHT99982.1 - 1.2e-05 25.1 0.3 1.3e-05 25.0 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1364) CPSF73-100_C PF11718.8 EHT99983.1 - 0.061 12.9 0.0 0.075 12.6 0.0 1.0 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Fer4_20 PF14691.6 EHT99985.1 - 0.02 14.6 0.7 0.033 13.9 0.7 1.4 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Imm45 PF15572.6 EHT99985.1 - 0.077 13.4 0.0 0.098 13.1 0.0 1.1 1 0 0 1 1 1 0 Immunity protein 45 Mvb12 PF09452.10 EHT99986.1 - 0.032 14.7 0.1 0.089 13.2 0.0 1.7 1 1 1 2 2 2 0 ESCRT-I subunit Mvb12 CobT PF06213.12 EHT99987.1 - 0.048 13.1 2.2 0.061 12.7 2.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4406 PF14359.6 EHT99989.1 - 2.9e-34 117.4 0.0 3.2e-34 117.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4406) DUF1937 PF09152.10 EHT99989.1 - 0.1 13.4 0.0 0.18 12.6 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1937) DnaB_C PF03796.15 EHT99990.1 - 5.5e-64 216.0 0.0 1.3e-63 214.8 0.0 1.5 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain DnaB PF00772.21 EHT99990.1 - 1e-31 109.0 0.0 2.4e-31 107.9 0.0 1.7 1 0 0 1 1 1 1 DnaB-like helicase N terminal domain AAA_25 PF13481.6 EHT99990.1 - 2.8e-14 53.1 0.2 7.4e-14 51.8 0.1 1.7 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 EHT99990.1 - 1.2e-07 31.3 0.1 3.9e-07 29.7 0.0 2.0 2 2 0 2 2 2 1 KaiC AAA_35 PF14516.6 EHT99990.1 - 0.19 10.5 0.0 0.42 9.4 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain Phage_rep_O PF04492.13 EHT99991.1 - 1.1e-30 106.1 0.0 2e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 Bacteriophage replication protein O DUF2740 PF10872.8 EHT99992.1 - 0.00089 19.1 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2740) SpoIIID PF12116.8 EHT99992.1 - 0.0082 16.2 0.1 0.0082 16.2 0.1 1.1 1 0 0 1 1 1 1 Stage III sporulation protein D Peptidase_S24 PF00717.23 EHT99995.1 - 8.2e-09 35.3 0.3 9.6e-09 35.1 0.3 1.1 1 0 0 1 1 1 1 Peptidase S24-like Phage_CI_C PF16452.5 EHT99995.1 - 0.0025 18.1 0.1 0.003 17.8 0.1 1.1 1 0 0 1 1 1 1 Bacteriophage CI repressor C-terminal domain DUF1482 PF07358.11 EHT99997.1 - 2.7e-10 40.0 0.1 3e-10 39.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1482) RNase_T PF00929.24 EHT99999.1 - 2.7e-19 70.3 0.0 2.5e-18 67.2 0.0 2.0 1 1 0 1 1 1 1 Exonuclease AAA_24 PF13479.6 EHU00001.1 - 6.8e-08 32.5 0.1 1.3e-07 31.6 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EHU00001.1 - 6.2e-06 26.5 0.0 6.5e-05 23.2 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EHU00001.1 - 0.0013 19.1 0.0 1.2 9.5 0.0 2.6 2 1 0 3 3 3 2 AAA ATPase domain Meiosis_expr PF15163.6 EHU00001.1 - 0.037 14.7 0.3 0.079 13.6 0.2 1.6 1 1 0 1 1 1 0 Meiosis-expressed MethyltransfD12 PF02086.15 EHU00003.1 - 1.2e-55 189.0 0.0 1.3e-55 188.9 0.0 1.0 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase DUF4060 PF13269.6 EHU00004.1 - 1.4e-37 127.6 0.7 1.6e-37 127.4 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4060) Arm-DNA-bind_3 PF13356.6 EHU00005.1 - 1.5e-16 60.5 0.3 3.1e-16 59.5 0.3 1.5 1 0 0 1 1 1 1 Arm DNA-binding domain Phage_integrase PF00589.22 EHU00005.1 - 1.1e-15 57.8 0.1 2.9e-15 56.5 0.0 1.7 3 0 0 3 3 3 1 Phage integrase family Phage_int_SAM_3 PF14659.6 EHU00005.1 - 0.00071 19.8 0.1 0.0017 18.6 0.1 1.6 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain DDE_3 PF13358.6 EHU00006.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHU00006.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHU00006.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHU00006.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHU00006.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHU00006.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHU00006.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHU00006.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 Arm-DNA-bind_3 PF13356.6 EHU00007.1 - 3.6e-19 68.9 0.1 6.6e-19 68.1 0.1 1.5 1 0 0 1 1 1 1 Arm DNA-binding domain Phage_integrase PF00589.22 EHU00007.1 - 9.1e-17 61.4 1.0 1.8e-16 60.4 0.0 1.9 2 1 0 2 2 2 1 Phage integrase family Phage_int_SAM_5 PF13102.6 EHU00007.1 - 0.14 12.5 0.0 19 5.7 0.0 2.7 3 0 0 3 3 3 0 Phage integrase SAM-like domain HTH_Tnp_1 PF01527.20 EHU00008.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU00008.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU00008.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU00008.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHU00009.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHU00010.1 - 1.2e-97 326.8 4.4 3.8e-97 325.1 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU00010.1 - 3.3e-16 59.2 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU00010.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU00010.1 - 8.7e-11 42.4 9.0 1.9e-10 41.4 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Phage_HK97_TLTM PF06120.11 EHU00010.1 - 0.029 13.6 0.7 0.056 12.6 0.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein UME PF08064.13 EHU00010.1 - 0.038 13.9 0.4 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain Exonuc_VII_L PF02601.15 EHU00010.1 - 0.041 13.4 2.5 0.044 13.4 0.9 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit FUSC PF04632.12 EHU00010.1 - 0.063 11.8 7.7 0.1 11.1 7.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Csm1_N PF18504.1 EHU00010.1 - 0.13 12.7 3.4 0.86 10.0 0.2 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Tho2 PF11262.8 EHU00010.1 - 0.17 11.1 0.3 0.28 10.4 0.3 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DHR10 PF18595.1 EHU00010.1 - 0.18 11.9 10.2 0.31 11.1 10.2 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain ERM PF00769.19 EHU00010.1 - 0.27 11.0 10.4 0.45 10.3 10.4 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family LXG PF04740.12 EHU00010.1 - 0.28 10.9 2.4 0.86 9.3 0.3 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily HHH_8 PF14716.6 EHU00010.1 - 0.34 11.3 4.0 0.56 10.6 1.9 2.4 2 1 0 2 2 2 0 Helix-hairpin-helix domain Zn-ribbon_8 PF09723.10 EHU00010.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain TSNAXIP1_N PF15739.5 EHU00010.1 - 0.45 10.9 3.2 0.99 9.8 3.2 1.5 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus FAM184 PF15665.5 EHU00010.1 - 0.49 10.1 7.3 0.78 9.5 7.3 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B TMPIT PF07851.13 EHU00010.1 - 0.77 8.9 2.7 1.2 8.4 2.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein CREPT PF16566.5 EHU00010.1 - 2.3 8.4 8.3 1.1 9.5 5.2 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour HAUS-augmin3 PF14932.6 EHU00010.1 - 2.5 7.6 7.4 5.8 6.4 7.4 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 SlyX PF04102.12 EHU00010.1 - 8.1 7.1 8.7 17 6.1 2.1 3.0 1 1 1 2 2 2 0 SlyX HTH_24 PF13412.6 EHU00011.1 - 1.2e-20 72.7 0.1 1.8e-20 72.2 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding AsnC_trans_reg PF01037.21 EHU00011.1 - 5e-18 64.8 0.3 7.7e-18 64.2 0.3 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_AsnC-type PF13404.6 EHU00011.1 - 6e-16 58.0 0.3 1e-15 57.2 0.3 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain MarR PF01047.22 EHU00011.1 - 1.8e-06 27.8 0.1 2.8e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 EHU00011.1 - 1.9e-05 24.5 0.1 4e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_11 PF08279.12 EHU00011.1 - 7.5e-05 22.6 0.1 0.00014 21.7 0.1 1.5 1 0 0 1 1 1 1 HTH domain HTH_20 PF12840.7 EHU00011.1 - 0.0015 18.6 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 EHU00011.1 - 0.014 15.3 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_IclR PF09339.10 EHU00011.1 - 0.023 14.5 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_CodY PF08222.11 EHU00011.1 - 0.032 13.8 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 CodY helix-turn-helix domain TrmB PF01978.19 EHU00011.1 - 0.079 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Fe_dep_repress PF01325.19 EHU00011.1 - 0.14 12.4 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain DUF1317 PF07026.11 EHU00012.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1317) Acyl_transf_3 PF01757.22 EHU00013.1 - 0.00011 21.5 26.2 0.00017 20.8 26.2 1.3 1 0 0 1 1 1 1 Acyltransferase family Flavi_NS4A PF01350.17 EHU00013.1 - 0.17 11.8 1.5 0.3 11.0 0.1 2.0 2 1 0 2 2 2 0 Flavivirus non-structural protein NS4A Aldedh PF00171.22 EHU00014.1 - 4.9e-116 388.0 0.6 7.9e-116 387.3 0.6 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pro_dh PF01619.18 EHU00014.1 - 2.3e-99 332.7 0.0 4.6e-99 331.7 0.0 1.5 1 0 0 1 1 1 1 Proline dehydrogenase Pro_dh-DNA_bdg PF14850.6 EHU00014.1 - 3.5e-46 156.3 0.0 9.4e-46 155.0 0.0 1.8 1 0 0 1 1 1 1 DNA-binding domain of Proline dehydrogenase PRODH PF18327.1 EHU00014.1 - 1.3e-16 60.6 11.8 2.6e-16 59.6 4.3 3.9 3 0 0 3 3 3 1 Proline utilization A proline dehydrogenase N-terminal domain RHH_1 PF01402.21 EHU00014.1 - 0.23 11.4 1.1 0.94 9.5 0.0 2.8 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family SSF PF00474.17 EHU00015.1 - 2.5e-136 454.8 28.9 3.8e-136 454.2 28.9 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family DUF4748 PF15932.5 EHU00015.1 - 0.0036 17.0 1.0 0.018 14.8 1.0 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) 4HB_MCP_1 PF12729.7 EHU00015.1 - 0.045 13.3 0.2 0.045 13.3 0.2 2.1 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction FTR1 PF03239.14 EHU00016.1 - 4.2e-69 233.1 16.6 5e-69 232.8 16.6 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Abhydrolase_9_N PF15420.6 EHU00016.1 - 4.6e-05 23.5 10.0 4.6e-05 23.5 10.0 2.1 1 1 1 2 2 2 1 Alpha/beta-hydrolase family N-terminus Popeye PF04831.13 EHU00016.1 - 0.2 11.8 7.6 2.3 8.4 2.8 2.5 2 0 0 2 2 2 0 Popeye protein conserved region DUF4271 PF14093.6 EHU00016.1 - 1.5 8.7 9.0 0.2 11.6 0.9 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4271) Peptidase_M75 PF09375.10 EHU00017.1 - 1.9e-43 149.0 4.7 2.5e-43 148.6 4.7 1.1 1 0 0 1 1 1 1 Imelysin Cupredoxin_1 PF13473.6 EHU00017.1 - 2e-23 82.5 0.0 3.3e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Cupredoxin-like domain DUF1843 PF08898.10 EHU00017.1 - 0.038 14.5 0.1 0.17 12.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) DUF4363 PF14276.6 EHU00017.1 - 0.096 12.8 0.0 1 9.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Apolipoprotein PF01442.18 EHU00017.1 - 0.17 11.7 2.5 8 6.3 0.1 2.7 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Dyp_perox PF04261.12 EHU00018.1 - 4.2e-113 377.6 0.0 4.9e-113 377.4 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family TAT_signal PF10518.9 EHU00018.1 - 0.0043 16.8 5.1 0.012 15.4 5.1 1.7 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence PhoH PF02562.16 EHU00019.1 - 7.3e-77 257.5 0.0 8.7e-77 257.2 0.0 1.1 1 0 0 1 1 1 1 PhoH-like protein AAA_30 PF13604.6 EHU00019.1 - 4.6e-09 36.3 0.0 9.7e-09 35.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EHU00019.1 - 1.1e-05 25.8 0.1 9.9e-05 22.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EHU00019.1 - 6.4e-05 23.3 0.0 0.022 15.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EHU00019.1 - 0.013 15.3 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DEAD PF00270.29 EHU00019.1 - 0.035 13.9 0.1 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 DEAD/DEAH box helicase UvrD-helicase PF00580.21 EHU00019.1 - 0.036 13.6 0.3 4.8 6.6 0.1 2.1 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain ResIII PF04851.15 EHU00019.1 - 0.051 13.6 0.0 0.18 11.8 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DEAD_2 PF06733.15 EHU00019.1 - 0.094 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 AAA_14 PF13173.6 EHU00019.1 - 0.094 12.7 0.0 5.8 7.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EHU00019.1 - 0.11 12.3 0.0 2 8.1 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 EHU00019.1 - 0.12 11.6 0.2 0.87 8.8 0.2 2.2 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Acyl-CoA_dh_2 PF08028.11 EHU00020.1 - 6.9e-08 32.9 10.6 6.9e-08 32.9 10.6 2.3 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EHU00020.1 - 3.4e-06 27.2 0.1 6.7e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EHU00020.1 - 4.9e-05 24.0 0.0 0.00024 21.7 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain FA_synthesis PF02504.15 EHU00020.1 - 0.032 13.3 0.8 0.046 12.8 0.8 1.1 1 0 0 1 1 1 0 Fatty acid synthesis protein Sugar_tr PF00083.24 EHU00021.1 - 5e-33 114.6 24.7 7e-33 114.2 24.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EHU00021.1 - 1.3e-25 90.1 51.0 1e-24 87.1 39.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EHU00021.1 - 1.1 7.5 6.6 2.5 6.3 0.5 2.4 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Bac_luciferase PF00296.20 EHU00022.1 - 2.4e-49 168.5 0.2 3e-49 168.1 0.2 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase NAD_binding_9 PF13454.6 EHU00023.1 - 1e-30 106.8 7.8 5.1e-29 101.3 0.9 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 EHU00023.1 - 2.8e-10 39.9 2.3 1.3e-06 27.8 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EHU00023.1 - 4.5e-10 39.2 0.0 6.3e-09 35.5 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EHU00023.1 - 1.8e-08 34.5 0.3 1.8e-06 28.1 0.2 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EHU00023.1 - 1.3e-07 32.0 0.5 0.00039 20.9 0.2 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EHU00023.1 - 2.3e-05 24.2 13.7 0.00037 20.2 13.7 2.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EHU00023.1 - 0.0018 17.2 0.1 0.0029 16.5 0.1 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 EHU00023.1 - 0.0066 15.7 0.0 0.72 9.0 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EHU00023.1 - 0.0076 15.3 0.5 0.019 14.0 0.5 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 EHU00023.1 - 0.023 13.8 0.2 2.1 7.4 0.2 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 EHU00023.1 - 0.14 10.8 0.1 0.33 9.6 0.1 1.6 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 EHU00023.1 - 0.19 10.9 0.1 0.38 10.0 0.1 1.5 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 EHU00023.1 - 2.5 7.1 12.5 6.4 5.7 10.4 2.6 1 1 0 2 2 2 0 FAD binding domain Bac_luciferase PF00296.20 EHU00024.1 - 8.7e-88 294.7 2.6 1.1e-87 294.5 2.6 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Sigma54_activat PF00158.26 EHU00025.1 - 3.9e-67 225.2 0.0 7.2e-67 224.3 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EHU00025.1 - 1.4e-20 73.8 0.0 4e-20 72.3 0.0 1.8 1 0 0 1 1 1 1 Sigma-54 interaction domain NMT1 PF09084.11 EHU00025.1 - 4.9e-13 49.5 0.0 7.5e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like AAA_5 PF07728.14 EHU00025.1 - 1.1e-08 35.2 0.0 2.9e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EHU00025.1 - 4.2e-05 24.0 0.0 7.9e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Phosphonate-bd PF12974.7 EHU00025.1 - 0.00034 20.3 0.0 0.00055 19.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 EHU00025.1 - 0.0007 19.1 0.0 0.0021 17.5 0.0 1.8 1 1 1 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_3 PF16868.5 EHU00025.1 - 0.0011 18.4 0.0 0.0024 17.3 0.0 1.5 1 1 0 1 1 1 1 NMT1-like family AAA_7 PF12775.7 EHU00025.1 - 0.0017 17.9 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region HTH_8 PF02954.19 EHU00025.1 - 0.0018 18.0 7.2 0.01 15.6 0.4 3.5 3 0 0 3 3 3 1 Bacterial regulatory protein, Fis family AAA_22 PF13401.6 EHU00025.1 - 0.0032 17.7 0.3 0.05 13.9 0.0 2.9 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EHU00025.1 - 0.016 14.6 0.0 2.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MCM PF00493.23 EHU00025.1 - 0.018 14.2 0.0 0.037 13.1 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain AAA_16 PF13191.6 EHU00025.1 - 0.019 15.3 2.3 0.035 14.5 0.4 2.5 2 1 0 2 2 2 0 AAA ATPase domain AAA_2 PF07724.14 EHU00025.1 - 0.042 14.0 0.0 0.1 12.7 0.0 1.6 2 0 0 2 2 1 0 AAA domain (Cdc48 subfamily) AAA_3 PF07726.11 EHU00025.1 - 0.073 12.9 0.1 0.2 11.5 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) OpuAC PF04069.12 EHU00025.1 - 0.17 11.5 0.0 0.29 10.7 0.0 1.5 1 1 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system NMT1 PF09084.11 EHU00026.1 - 1.2e-16 61.3 0.0 1.5e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 EHU00026.1 - 1.9e-13 50.7 0.2 2.6e-13 50.2 0.2 1.2 1 0 0 1 1 1 1 NMT1-like family OpuAC PF04069.12 EHU00026.1 - 1e-09 38.4 0.7 1.5e-09 37.8 0.7 1.2 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system NMT1_3 PF16868.5 EHU00026.1 - 3.6e-08 33.2 0.0 5.4e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 EHU00026.1 - 2e-07 30.9 0.1 5.8e-07 29.3 0.1 1.8 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 EHU00026.1 - 2.5e-07 30.4 0.0 3.6e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ETF PF01012.21 EHU00026.1 - 0.0088 15.9 0.4 0.014 15.3 0.2 1.5 2 0 0 2 2 2 1 Electron transfer flavoprotein domain PS_Dcarbxylase PF02666.15 EHU00026.1 - 0.062 12.8 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylserine decarboxylase PMSR PF01625.21 EHU00027.1 - 9.4e-62 207.7 0.1 1.1e-61 207.5 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase HATPase_c PF02518.26 EHU00029.1 - 3.3e-15 56.6 0.2 7.1e-15 55.5 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EHU00029.1 - 5e-09 36.1 4.1 5.4e-09 36.0 1.9 2.3 2 1 1 3 3 3 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 EHU00029.1 - 0.0052 17.1 0.2 0.039 14.3 0.0 2.6 3 0 0 3 3 3 1 HAMP domain VMA21 PF09446.10 EHU00029.1 - 0.099 12.8 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 VMA21-like domain Response_reg PF00072.24 EHU00030.1 - 2.5e-25 88.8 0.1 3.7e-25 88.3 0.1 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 EHU00030.1 - 9.1e-21 73.7 0.6 3.2e-20 72.0 0.0 2.1 3 0 0 3 3 3 1 Transcriptional regulatory protein, C terminal FleQ PF06490.11 EHU00030.1 - 0.0044 17.4 0.0 0.0063 16.9 0.0 1.3 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ DUF1891 PF09004.10 EHU00030.1 - 0.11 12.2 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1891) Trehalose_PPase PF02358.16 EHU00031.1 - 1e-46 159.0 0.0 1.2e-46 158.7 0.0 1.0 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 EHU00031.1 - 1.8e-07 31.2 0.0 0.0048 16.7 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Glyco_transf_20 PF00982.21 EHU00032.1 - 2.8e-138 461.6 0.0 3.1e-138 461.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 FlhD PF05247.13 EHU00034.1 - 4.5e-40 136.1 2.8 5.1e-40 135.9 2.8 1.0 1 0 0 1 1 1 1 Flagellar transcriptional activator (FlhD) DUF2857 PF11198.8 EHU00034.1 - 0.00091 19.0 0.9 0.0011 18.8 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2857) FlhC PF05280.11 EHU00035.1 - 2.7e-80 268.1 0.0 3.1e-80 267.9 0.0 1.0 1 0 0 1 1 1 1 Flagellar transcriptional activator (FlhC) MotA_ExbB PF01618.16 EHU00036.1 - 2.7e-11 43.3 0.3 4.6e-11 42.6 0.3 1.4 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family Podoplanin PF05808.11 EHU00036.1 - 0.1 12.7 0.4 0.33 11.0 0.1 1.9 1 1 1 2 2 2 0 Podoplanin SpoVAB PF13782.6 EHU00036.1 - 1 9.7 8.5 2.5 8.4 2.4 2.3 2 0 0 2 2 2 0 Stage V sporulation protein AB MotB_plug PF13677.6 EHU00037.1 - 1e-20 73.1 0.4 2.5e-20 71.8 0.4 1.7 1 0 0 1 1 1 1 Membrane MotB of proton-channel complex MotA/MotB OmpA PF00691.20 EHU00037.1 - 9.6e-14 51.5 0.0 3e-13 49.9 0.0 1.9 1 0 0 1 1 1 1 OmpA family DUF572 PF04502.13 EHU00037.1 - 6.6 6.2 7.9 11 5.5 7.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) CCDC24 PF15669.5 EHU00037.1 - 7.3 6.4 13.3 50 3.7 13.1 2.2 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 24 family CheW PF01584.19 EHU00038.1 - 1.2e-25 89.7 0.5 2.9e-25 88.5 0.5 1.6 1 0 0 1 1 1 1 CheW-like domain Hpt PF01627.23 EHU00038.1 - 2.5e-20 72.5 1.6 1.2e-19 70.4 0.3 2.6 2 0 0 2 2 2 1 Hpt domain CheY-binding PF09078.11 EHU00038.1 - 1.6e-19 69.7 0.7 5.5e-19 68.0 0.7 2.0 1 0 0 1 1 1 1 CheY binding H-kinase_dim PF02895.14 EHU00038.1 - 8.2e-19 67.8 1.3 3.1e-18 65.9 1.3 2.1 1 0 0 1 1 1 1 Signal transducing histidine kinase, homodimeric domain HATPase_c PF02518.26 EHU00038.1 - 4.1e-17 62.7 0.1 1.2e-16 61.3 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CheW PF01584.19 EHU00039.1 - 5.6e-38 129.7 1.8 6.6e-38 129.5 1.8 1.1 1 0 0 1 1 1 1 CheW-like domain Peptidase_M23_N PF18421.1 EHU00039.1 - 0.027 14.4 0.4 0.041 13.8 0.4 1.3 1 0 0 1 1 1 0 Peptidase family M23 N-terminal domain MCPsignal PF00015.21 EHU00040.1 - 1.2e-60 204.2 31.0 9.5e-60 201.3 16.6 2.9 3 0 0 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain TarH PF02203.15 EHU00040.1 - 7.4e-31 107.4 11.7 7.4e-31 107.4 11.7 3.8 5 0 0 5 5 5 1 Tar ligand binding domain homologue HAMP PF00672.25 EHU00040.1 - 1.2e-08 35.2 6.6 1.6e-08 34.7 0.2 4.2 4 1 0 4 4 4 1 HAMP domain Trep_Strep PF09605.10 EHU00040.1 - 0.34 10.9 3.1 0.3 11.0 0.3 2.1 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF948 PF06103.11 EHU00040.1 - 0.92 9.8 17.1 12 6.2 2.5 4.9 1 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) MCPsignal PF00015.21 EHU00041.1 - 9.5e-59 198.1 33.5 3.4e-58 196.3 16.7 2.8 3 0 0 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain TarH PF02203.15 EHU00041.1 - 2.2e-42 145.0 0.6 2.2e-42 145.0 0.6 4.1 4 1 0 4 4 4 1 Tar ligand binding domain homologue HAMP PF00672.25 EHU00041.1 - 1.3e-09 38.3 0.8 1.3e-09 38.3 0.8 3.1 4 1 0 4 4 4 1 HAMP domain YscO PF07321.12 EHU00041.1 - 0.02 14.9 1.0 0.02 14.9 1.0 3.0 3 0 0 3 3 3 0 Type III secretion protein YscO Tox-URI2 PF15653.6 EHU00041.1 - 0.059 13.6 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 URI fold toxin 2 DUF1673 PF07895.11 EHU00041.1 - 0.11 12.2 0.2 0.2 11.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) SAM_LFY PF01698.16 EHU00041.1 - 0.12 12.3 0.1 0.52 10.3 0.0 2.1 2 0 0 2 2 2 0 Floricaula / Leafy protein SAM domain Prominin PF05478.11 EHU00041.1 - 0.78 7.6 5.7 0.17 9.8 1.1 2.1 2 1 1 3 3 3 0 Prominin DUF1664 PF07889.12 EHU00041.1 - 2.3 8.3 12.3 2 8.4 1.4 3.5 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) DUF4854 PF16146.5 EHU00041.1 - 8 6.9 7.6 1 9.7 0.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4854) CheR PF01739.18 EHU00042.1 - 1.7e-58 197.3 0.0 2.6e-58 196.7 0.0 1.2 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain CheR_N PF03705.15 EHU00042.1 - 7.8e-18 63.9 1.4 1.4e-17 63.1 1.4 1.4 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain Methyltransf_12 PF08242.12 EHU00042.1 - 1.1e-06 29.3 0.0 2.2e-05 25.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EHU00042.1 - 1.4e-06 28.9 0.0 0.00013 22.6 0.0 2.9 2 1 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 EHU00042.1 - 0.0005 20.7 0.0 0.0017 19.0 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EHU00042.1 - 0.0084 15.9 0.0 0.059 13.2 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 EHU00042.1 - 0.045 13.6 0.0 0.068 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CheB_methylest PF01339.17 EHU00043.1 - 9.2e-62 207.7 0.1 1.7e-61 206.8 0.1 1.4 1 0 0 1 1 1 1 CheB methylesterase Response_reg PF00072.24 EHU00043.1 - 3e-24 85.3 0.2 8e-24 84.0 0.2 1.7 1 0 0 1 1 1 1 Response regulator receiver domain Response_reg PF00072.24 EHU00044.1 - 4.7e-32 110.5 0.0 5.3e-32 110.3 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain SBP_bac_3 PF00497.20 EHU00044.1 - 0.0091 15.4 0.5 0.87 9.0 0.2 2.0 1 1 1 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 CheZ PF04344.13 EHU00045.1 - 1.3e-74 250.5 3.3 1.5e-74 250.3 3.3 1.0 1 0 0 1 1 1 1 Chemotaxis phosphatase, CheZ Laminin_I PF06008.14 EHU00045.1 - 0.0055 16.4 0.8 0.0055 16.4 0.8 2.1 2 1 0 2 2 2 1 Laminin Domain I Lipoprotein_20 PF13942.6 EHU00045.1 - 0.096 12.6 0.5 0.97 9.3 0.1 2.3 1 1 1 2 2 2 0 YfhG lipoprotein DUF637 PF04830.13 EHU00045.1 - 0.11 12.3 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 Possible hemagglutinin (DUF637) Delta_lysin PF05372.11 EHU00045.1 - 0.16 11.3 1.6 0.21 10.9 0.1 1.9 2 0 0 2 2 2 0 Delta lysin family phage_tail_N PF08400.10 EHU00045.1 - 0.17 11.9 2.8 4 7.4 0.1 2.2 2 0 0 2 2 2 0 Prophage tail fibre N-terminal Bac_export_2 PF01312.19 EHU00046.1 - 1.3e-125 419.0 0.2 1.5e-125 418.8 0.2 1.0 1 0 0 1 1 1 1 FlhB HrpN YscU SpaS Family TetR_C_21 PF17926.1 EHU00046.1 - 0.37 10.9 0.1 0.37 10.9 0.1 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain FHIPEP PF00771.20 EHU00047.1 - 2.3e-268 892.1 4.9 2.7e-268 891.9 4.9 1.0 1 0 0 1 1 1 1 FHIPEP family FlhE PF06366.13 EHU00048.1 - 4e-32 110.4 0.0 4.6e-32 110.2 0.0 1.0 1 0 0 1 1 1 1 Flagellar protein FlhE MIP PF00230.20 EHU00049.1 - 4.9e-48 163.8 17.4 5.6e-48 163.6 17.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein HXXEE PF13787.6 EHU00049.1 - 1.7 9.5 11.7 0.13 13.1 1.7 2.5 1 1 0 2 2 2 0 Protein of unknown function with HXXEE motif tRNA-synt_1d PF00750.19 EHU00051.1 - 2.5e-165 549.6 0.2 3.1e-165 549.3 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EHU00051.1 - 1.1e-33 115.9 0.0 4e-33 114.1 0.1 2.0 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 EHU00051.1 - 6.9e-22 77.8 0.1 1.9e-21 76.4 0.1 1.8 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.19 EHU00051.1 - 8.2e-05 22.1 0.1 0.00014 21.3 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EHU00051.1 - 0.022 13.5 0.0 0.043 12.6 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EHU00051.1 - 0.033 12.4 0.0 0.05 11.8 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) FeoB_associated PF12669.7 EHU00052.1 - 0.012 16.0 1.9 0.013 15.8 1.9 1.2 1 1 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF2162 PF09930.9 EHU00052.1 - 0.052 12.9 0.2 0.054 12.9 0.2 1.0 1 0 0 1 1 1 0 Predicted transporter (DUF2162) DUF2542 PF10808.8 EHU00052.1 - 0.062 13.8 0.4 0.075 13.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2542) YecM PF06185.12 EHU00053.1 - 7.2e-68 227.8 0.0 8.1e-68 227.6 0.0 1.0 1 0 0 1 1 1 1 YecM protein Aminotran_1_2 PF00155.21 EHU00054.1 - 1.2e-27 97.1 0.0 1.4e-27 96.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EHU00054.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase CutC PF03932.14 EHU00055.1 - 2.6e-71 239.3 0.0 3.4e-71 238.9 0.0 1.1 1 0 0 1 1 1 1 CutC family RHS_repeat PF05593.14 EHU00056.1 - 2.2 8.9 17.9 0.37 11.4 3.2 3.9 2 1 2 4 4 4 0 RHS Repeat Fe-ADH PF00465.19 EHU00057.1 - 2.1e-63 214.4 1.1 2.5e-63 214.1 1.1 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EHU00057.1 - 6.2e-36 124.4 1.6 7.6e-36 124.1 1.6 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 EHU00057.1 - 0.0001 21.6 1.2 0.0019 17.4 1.2 2.6 1 1 0 1 1 1 1 3-dehydroquinate synthase AIRC PF00731.20 EHU00057.1 - 0.0047 16.5 0.0 0.0099 15.5 0.0 1.5 1 0 0 1 1 1 1 AIR carboxylase PFK PF00365.20 EHU00057.1 - 0.0087 15.4 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Phosphofructokinase Polysacc_deac_2 PF04748.13 EHU00057.1 - 0.077 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase DUF1580 PF07618.11 EHU00057.1 - 0.13 11.9 0.1 0.36 10.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1580) LysE PF01810.18 EHU00058.1 - 1.3e-36 125.9 8.6 1.5e-36 125.7 8.6 1.0 1 0 0 1 1 1 1 LysE type translocator TerC PF03741.16 EHU00058.1 - 0.0043 16.7 0.3 0.0059 16.3 0.3 1.6 1 1 0 1 1 1 1 Integral membrane protein TerC family SPT_ssu-like PF11779.8 EHU00058.1 - 3.1 7.5 5.3 2.2 8.0 0.1 2.5 2 0 0 2 2 2 0 Small subunit of serine palmitoyltransferase-like Methyltransf_9 PF08003.11 EHU00059.1 - 5.6e-163 541.3 0.0 6.3e-163 541.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 EHU00059.1 - 1.3e-10 41.4 0.0 2.5e-10 40.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EHU00059.1 - 2.9e-09 36.9 0.0 7.5e-09 35.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EHU00059.1 - 1.7e-07 31.8 0.0 5.3e-07 30.2 0.0 1.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 EHU00059.1 - 2.3e-07 31.4 0.0 5.4e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EHU00059.1 - 8.8e-06 26.4 0.0 1.7e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EHU00059.1 - 6.4e-05 22.4 0.0 9.1e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 EHU00059.1 - 0.0023 17.7 0.1 0.008 15.9 0.1 1.8 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF4568 PF15132.6 EHU00059.1 - 0.078 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4568) Methyltransf_25 PF13649.6 EHU00060.1 - 2.2e-12 47.5 0.0 4.4e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EHU00060.1 - 4.9e-10 39.9 0.0 9e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EHU00060.1 - 5.4e-08 32.8 0.0 9e-08 32.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EHU00060.1 - 1.3e-07 31.6 0.0 1.7e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EHU00060.1 - 2e-07 31.7 0.0 3.3e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EHU00060.1 - 1.9e-06 27.3 0.0 2.7e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Rsm22 PF09243.10 EHU00060.1 - 0.00037 19.9 0.0 0.00063 19.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 MTS PF05175.14 EHU00060.1 - 0.00038 20.1 0.0 0.00055 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CheR PF01739.18 EHU00060.1 - 0.00086 18.8 0.0 1.1 8.7 0.0 2.2 1 1 0 2 2 2 2 CheR methyltransferase, SAM binding domain PrmA PF06325.13 EHU00060.1 - 0.0026 17.2 0.0 0.0036 16.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 EHU00060.1 - 0.014 15.2 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 EHU00060.1 - 0.036 14.2 0.1 0.065 13.3 0.1 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_18 PF12847.7 EHU00060.1 - 0.057 13.4 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 EHU00060.1 - 0.061 13.0 0.0 0.099 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 MetW PF07021.12 EHU00060.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MAPEG PF01124.18 EHU00061.1 - 5.4e-24 84.5 5.3 6.2e-24 84.4 5.3 1.0 1 0 0 1 1 1 1 MAPEG family DUF72 PF01904.18 EHU00062.1 - 2e-45 155.6 0.3 2.7e-45 155.2 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF72 tRNA-synt_2 PF00152.20 EHU00063.1 - 5.3e-107 357.5 0.0 6.6e-107 357.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) GAD PF02938.14 EHU00063.1 - 7.8e-30 103.0 0.1 1.5e-29 102.1 0.1 1.5 1 0 0 1 1 1 1 GAD domain tRNA_anti-codon PF01336.25 EHU00063.1 - 1.8e-15 56.7 0.0 3.5e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EHU00063.1 - 0.00053 19.5 0.1 0.48 9.8 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.25 EHU00063.1 - 0.039 13.9 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) SUKH-4 PF14435.6 EHU00063.1 - 0.11 12.5 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 SUKH-4 immunity protein NUDIX PF00293.28 EHU00064.1 - 2.8e-18 66.2 0.8 3.1e-18 66.1 0.8 1.0 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 EHU00064.1 - 0.011 15.7 0.7 0.016 15.2 0.7 1.3 1 1 0 1 1 1 0 NUDIX domain Transcrip_reg PF01709.20 EHU00066.1 - 8.5e-94 313.5 0.0 9.6e-94 313.3 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator RuvC PF02075.17 EHU00067.1 - 3.1e-65 218.6 0.4 3.7e-65 218.3 0.4 1.1 1 0 0 1 1 1 1 Crossover junction endodeoxyribonuclease RuvC DUF3882 PF07066.11 EHU00067.1 - 0.012 15.7 0.0 0.025 14.6 0.0 1.7 1 1 0 1 1 1 0 Lactococcus phage M3 protein RuvA_N PF01330.21 EHU00068.1 - 3.4e-19 68.7 0.1 2.1e-18 66.2 0.0 2.2 2 1 0 2 2 2 1 RuvA N terminal domain HHH_5 PF14520.6 EHU00068.1 - 3.4e-17 62.8 1.0 6.5e-17 61.9 0.4 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain RuvA_C PF07499.13 EHU00068.1 - 8.2e-15 55.0 0.3 8.2e-15 55.0 0.3 2.0 2 0 0 2 2 2 1 RuvA, C-terminal domain HHH PF00633.23 EHU00068.1 - 1.5e-09 37.2 1.1 0.0017 18.1 0.2 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix motif IMS_HHH PF11798.8 EHU00068.1 - 0.0005 20.3 0.1 0.071 13.5 0.0 2.6 2 0 0 2 2 2 1 IMS family HHH motif HHH_2 PF12826.7 EHU00068.1 - 0.0017 18.4 0.0 0.66 10.1 0.0 2.7 2 1 1 3 3 3 1 Helix-hairpin-helix motif HHH_3 PF12836.7 EHU00068.1 - 0.0023 18.1 0.1 0.3 11.4 0.1 2.4 1 1 1 2 2 2 2 Helix-hairpin-helix motif HHH_8 PF14716.6 EHU00068.1 - 0.0035 17.7 0.0 0.44 11.0 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain Transposase_20 PF02371.16 EHU00068.1 - 0.009 16.3 0.0 0.71 10.2 0.0 2.5 2 0 0 2 2 2 1 Transposase IS116/IS110/IS902 family FeS_assembly_P PF01883.19 EHU00068.1 - 0.055 13.7 0.2 0.25 11.5 0.1 2.0 2 0 0 2 2 2 0 Iron-sulfur cluster assembly protein 5_3_exonuc PF01367.20 EHU00068.1 - 0.076 13.6 0.2 7.3 7.3 0.0 2.3 1 1 1 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF3173 PF11372.8 EHU00068.1 - 0.15 12.0 0.0 1.9 8.4 0.0 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF3173) RuvB_N PF05496.12 EHU00069.1 - 2e-82 274.6 0.0 2.8e-82 274.2 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_4 PF17864.1 EHU00069.1 - 9.7e-31 105.3 0.2 1.9e-30 104.5 0.2 1.5 1 0 0 1 1 1 1 RuvB AAA lid domain RuvB_C PF05491.13 EHU00069.1 - 3.1e-28 97.4 0.0 5.9e-28 96.5 0.0 1.5 1 0 0 1 1 1 1 RuvB C-terminal winged helix domain AAA PF00004.29 EHU00069.1 - 7.6e-20 71.7 0.0 1.9e-19 70.4 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EHU00069.1 - 1.2e-08 35.0 0.0 5.3e-06 26.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EHU00069.1 - 7.1e-05 23.1 0.1 0.031 14.6 0.0 2.5 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EHU00069.1 - 9.8e-05 21.8 0.2 0.037 13.4 0.0 2.5 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EHU00069.1 - 0.0002 21.2 0.0 0.15 12.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EHU00069.1 - 0.0003 20.7 0.0 0.00047 20.1 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain TIP49 PF06068.13 EHU00069.1 - 0.0004 19.7 0.4 0.0029 16.9 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_16 PF13191.6 EHU00069.1 - 0.001 19.5 0.4 0.097 13.1 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain Sigma54_activat PF00158.26 EHU00069.1 - 0.0012 18.6 0.0 1.3 8.7 0.0 2.3 1 1 1 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.6 EHU00069.1 - 0.0044 17.1 0.0 0.0091 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EHU00069.1 - 0.0098 16.4 0.0 0.018 15.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 EHU00069.1 - 0.021 14.7 0.2 0.15 11.9 0.0 2.1 1 1 1 2 2 2 0 NTPase RNA_helicase PF00910.22 EHU00069.1 - 0.028 14.8 0.0 0.056 13.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 EHU00069.1 - 0.04 13.9 0.0 0.073 13.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 EHU00069.1 - 0.046 13.4 0.0 0.12 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 EHU00069.1 - 0.061 12.5 0.0 1.3 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Bac_DnaA PF00308.18 EHU00069.1 - 0.062 13.1 0.0 0.42 10.4 0.0 2.0 2 0 0 2 2 2 0 Bacterial dnaA protein MCM PF00493.23 EHU00069.1 - 0.065 12.3 0.0 2.3 7.3 0.0 2.2 1 1 0 1 1 1 0 MCM P-loop domain AAA_17 PF13207.6 EHU00069.1 - 0.067 13.6 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EHU00069.1 - 0.07 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 EHU00069.1 - 0.071 12.8 0.1 0.37 10.5 0.1 2.2 1 1 0 1 1 1 0 IstB-like ATP binding protein NB-ARC PF00931.22 EHU00069.1 - 0.074 12.2 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain TniB PF05621.11 EHU00069.1 - 0.1 12.0 0.1 2.2 7.6 0.0 2.1 1 1 1 2 2 2 0 Bacterial TniB protein AAA_19 PF13245.6 EHU00069.1 - 0.14 12.5 0.6 2.2 8.6 0.1 2.3 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 EHU00069.1 - 0.17 12.4 0.0 0.31 11.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter ABC-3 PF00950.17 EHU00070.1 - 6.8e-83 278.1 26.5 7.6e-83 278.0 26.5 1.0 1 0 0 1 1 1 1 ABC 3 transport family FecCD PF01032.18 EHU00070.1 - 2.2e-06 26.9 27.5 2.8e-06 26.5 27.5 1.2 1 0 0 1 1 1 1 FecCD transport family ABC_tran PF00005.27 EHU00071.1 - 4.2e-29 101.8 0.0 6.4e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EHU00071.1 - 1.5e-07 31.5 1.6 0.009 15.8 0.1 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EHU00071.1 - 0.0001 22.0 0.1 0.0002 21.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EHU00071.1 - 0.0001 22.6 0.0 0.00018 21.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EHU00071.1 - 0.0026 17.4 0.6 0.67 9.5 0.1 2.2 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 EHU00071.1 - 0.003 17.0 0.1 0.28 10.6 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EHU00071.1 - 0.0041 17.0 0.3 0.014 15.3 0.1 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EHU00071.1 - 0.0094 16.3 0.4 0.017 15.5 0.4 1.5 1 1 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.9 EHU00071.1 - 0.01 14.6 0.2 0.86 8.3 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Rad17 PF03215.15 EHU00071.1 - 0.011 15.6 0.1 0.029 14.3 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain Mg_chelatase PF01078.21 EHU00071.1 - 0.018 14.4 0.1 0.041 13.3 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MutS_V PF00488.21 EHU00071.1 - 0.023 14.7 0.1 7.9 6.5 0.0 2.1 2 0 0 2 2 2 0 MutS domain V AAA_23 PF13476.6 EHU00071.1 - 0.031 14.8 0.0 0.04 14.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 EHU00071.1 - 0.066 12.8 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EHU00071.1 - 0.087 12.5 0.0 0.13 11.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EHU00071.1 - 0.12 12.3 0.8 1.3 9.0 0.1 2.2 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 EHU00071.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 EHU00071.1 - 0.17 12.3 0.1 0.37 11.2 0.1 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_PrkA PF08298.11 EHU00071.1 - 0.19 10.6 0.2 0.28 10.1 0.2 1.2 1 0 0 1 1 1 0 PrkA AAA domain ZnuA PF01297.17 EHU00072.1 - 2.5e-58 197.5 0.0 2.8e-58 197.3 0.0 1.0 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic Peptidase_M23 PF01551.22 EHU00073.1 - 4.7e-35 119.7 0.4 8.5e-35 118.9 0.4 1.4 1 0 0 1 1 1 1 Peptidase family M23 OapA PF04225.12 EHU00073.1 - 1.5e-10 41.0 0.3 3.7e-09 36.6 0.0 2.6 2 0 0 2 2 2 1 Opacity-associated protein A LysM-like domain OapA_N PF08525.11 EHU00073.1 - 4.3e-09 36.1 0.1 8.3e-09 35.2 0.1 1.5 1 0 0 1 1 1 1 Opacity-associated protein A N-terminal motif LysM PF01476.20 EHU00073.1 - 1.2e-05 25.3 1.0 2.8e-05 24.1 0.1 2.1 2 0 0 2 2 2 1 LysM domain Biotin_lipoyl_2 PF13533.6 EHU00073.1 - 0.082 12.7 0.1 0.19 11.6 0.1 1.7 1 0 0 1 1 1 0 Biotin-lipoyl like Amidase_5 PF05382.13 EHU00073.1 - 0.092 12.7 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage peptidoglycan hydrolase Lip_A_acyltrans PF03279.13 EHU00074.1 - 4e-97 325.0 0.0 4.5e-97 324.8 0.0 1.0 1 0 0 1 1 1 1 Bacterial lipid A biosynthesis acyltransferase DUF1729 PF08354.10 EHU00074.1 - 0.026 13.4 0.0 0.042 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) MFS_1 PF07690.16 EHU00075.1 - 5.6e-34 117.6 45.3 1.9e-33 115.9 34.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EHU00075.1 - 3.3e-08 32.8 20.6 1.9e-06 27.0 0.5 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter DUF2755 PF10954.8 EHU00075.1 - 0.77 9.7 4.6 0.19 11.7 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2755) PK PF00224.21 EHU00076.1 - 6.9e-129 429.7 5.2 9.2e-129 429.3 5.2 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EHU00076.1 - 1.4e-28 99.4 0.4 4.9e-28 97.7 0.1 2.1 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain DUF2737 PF10930.8 EHU00076.1 - 0.13 11.9 0.3 0.31 10.7 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2737) G6PD_C PF02781.16 EHU00078.1 - 2.3e-118 394.6 0.0 3.1e-118 394.2 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 EHU00078.1 - 1.6e-58 198.2 0.0 2.8e-58 197.4 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 EHU00078.1 - 0.007 17.2 0.0 0.014 16.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Aldolase PF01081.19 EHU00079.1 - 6.1e-91 303.2 1.0 6.9e-91 303.0 1.0 1.0 1 0 0 1 1 1 1 KDPG and KHG aldolase HMGL-like PF00682.19 EHU00079.1 - 0.04 13.5 0.2 0.056 13.0 0.2 1.2 1 0 0 1 1 1 0 HMGL-like ATP-grasp PF02222.22 EHU00080.1 - 1e-56 191.2 0.0 1.6e-56 190.6 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 EHU00080.1 - 4.8e-07 29.5 0.0 8.9e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 EHU00080.1 - 1.5e-05 24.7 0.0 5.9e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus Epimerase PF01370.21 EHU00080.1 - 2e-05 24.2 0.0 5.6e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family ATP-grasp_3 PF02655.14 EHU00080.1 - 6e-05 23.1 0.0 0.00019 21.5 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain 2-Hacid_dh_C PF02826.19 EHU00080.1 - 0.00014 21.3 0.0 0.00024 20.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain LAL_C2 PF18603.1 EHU00080.1 - 0.025 14.8 1.0 0.066 13.4 1.0 1.7 1 0 0 1 1 1 0 L-amino acid ligase C-terminal domain 2 RmlD_sub_bind PF04321.17 EHU00080.1 - 0.042 12.9 0.1 0.069 12.2 0.1 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain ATP-grasp_4 PF13535.6 EHU00080.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain DUF533 PF04391.12 EHU00081.1 - 3.3e-50 170.2 0.6 3.8e-50 169.9 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF533) TerB PF05099.13 EHU00081.1 - 0.0025 17.8 0.7 0.005 16.8 0.5 1.6 1 1 0 1 1 1 1 Tellurite resistance protein TerB Spore_III_AB PF09548.10 EHU00081.1 - 0.039 14.1 0.0 0.069 13.3 0.0 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Peptidase_S9_N PF02897.15 EHU00082.1 - 2.1e-63 214.6 6.1 2.5e-63 214.3 6.1 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain PD40 PF07676.12 EHU00082.1 - 0.038 13.9 0.0 0.13 12.3 0.1 1.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat HTH_Tnp_1 PF01527.20 EHU00083.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU00083.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU00083.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU00083.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHU00084.1 - 2e-08 34.0 0.0 2.2e-08 33.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHU00085.1 - 8.3e-98 327.3 4.4 3e-97 325.5 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family zf-IS66 PF13005.7 EHU00085.1 - 1.3e-14 54.3 1.5 3.1e-14 53.1 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU00085.1 - 7.4e-11 42.7 9.0 1.6e-10 41.6 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Phage_HK97_TLTM PF06120.11 EHU00085.1 - 0.025 13.8 0.7 0.05 12.8 0.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein UME PF08064.13 EHU00085.1 - 0.029 14.3 0.4 19 5.2 0.0 3.1 2 1 1 3 3 3 0 UME (NUC010) domain Exonuc_VII_L PF02601.15 EHU00085.1 - 0.034 13.7 2.5 0.037 13.6 0.9 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit FUSC PF04632.12 EHU00085.1 - 0.054 12.0 7.7 0.088 11.3 7.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Csm1_N PF18504.1 EHU00085.1 - 0.11 12.8 3.6 0.77 10.1 0.2 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Tho2 PF11262.8 EHU00085.1 - 0.15 11.2 0.3 0.25 10.5 0.3 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DHR10 PF18595.1 EHU00085.1 - 0.15 12.1 10.2 0.27 11.3 10.2 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain ERM PF00769.19 EHU00085.1 - 0.19 11.5 10.1 0.32 10.8 10.1 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family LXG PF04740.12 EHU00085.1 - 0.23 11.1 2.4 0.77 9.4 0.3 2.2 1 1 1 2 2 2 0 LXG domain of WXG superfamily Zn-ribbon_8 PF09723.10 EHU00085.1 - 0.31 11.2 1.7 0.92 9.7 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain HHH_8 PF14716.6 EHU00085.1 - 0.31 11.4 4.1 0.79 10.1 2.6 2.4 2 1 0 2 2 2 0 Helix-hairpin-helix domain TSNAXIP1_N PF15739.5 EHU00085.1 - 0.39 11.1 3.2 0.87 10.0 3.2 1.6 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus FAM184 PF15665.5 EHU00085.1 - 0.43 10.3 7.3 0.69 9.7 7.3 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B TMPIT PF07851.13 EHU00085.1 - 0.68 9.1 2.7 1 8.5 2.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein CREPT PF16566.5 EHU00085.1 - 1.9 8.7 8.3 0.92 9.7 5.2 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour HAUS-augmin3 PF14932.6 EHU00085.1 - 2.1 7.9 7.4 5.1 6.6 7.4 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHU00085.1 - 8.3 6.7 8.5 16 5.8 8.5 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 EHU00085.1 - 8.5 7.1 9.1 21 5.9 2.5 3.1 1 1 1 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHU00086.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHU00087.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU00087.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU00087.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU00087.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix LysE PF01810.18 EHU00088.1 - 4e-22 78.6 21.2 4.9e-22 78.3 21.2 1.0 1 0 0 1 1 1 1 LysE type translocator TetR_C_29 PF17938.1 EHU00089.1 - 5.1e-38 129.8 0.3 9.7e-38 128.9 0.3 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 EHU00089.1 - 5.6e-10 38.8 0.1 8.9e-10 38.2 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_21 PF17926.1 EHU00089.1 - 0.00039 20.5 0.0 0.00068 19.7 0.0 1.5 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_4 PF08359.11 EHU00089.1 - 0.0018 18.4 0.1 0.0028 17.8 0.1 1.5 1 1 0 1 1 1 1 YsiA-like protein, C-terminal region TetR_C_24 PF17932.1 EHU00089.1 - 0.014 15.7 0.0 0.035 14.4 0.0 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TetR_C_15 PF17918.1 EHU00089.1 - 0.029 15.1 0.0 0.078 13.7 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Pro-rich_19 PF15455.6 EHU00089.1 - 0.087 11.9 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Proline-rich 19 SporV_AA PF12164.8 EHU00089.1 - 0.12 12.7 0.1 0.3 11.5 0.1 1.6 1 0 0 1 1 1 0 Stage V sporulation protein AA ALO PF04030.14 EHU00090.1 - 1.2e-42 146.6 0.1 1.8e-42 145.9 0.1 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 EHU00090.1 - 2.9e-15 56.2 0.0 5.7e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Polyketide_cyc PF03364.20 EHU00090.1 - 0.023 14.9 0.0 0.049 13.8 0.0 1.5 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport YbjN PF10722.9 EHU00090.1 - 0.06 13.4 0.6 0.12 12.4 0.6 1.6 1 0 0 1 1 1 0 Putative bacterial sensory transduction regulator Glyco_transf_8 PF01501.20 EHU00091.1 - 0.00013 21.6 0.0 0.00016 21.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Caudo_TAP PF02413.17 EHU00092.1 - 3.8e-23 82.1 0.0 4.6e-23 81.8 0.0 1.0 1 0 0 1 1 1 1 Caudovirales tail fibre assembly protein, lambda gpK DUF2313 PF10076.9 EHU00093.1 - 4.1e-35 121.0 0.0 4.7e-35 120.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2313) Nif11 PF07862.11 EHU00093.1 - 0.08 13.3 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Nif11 domain RHH_1 PF01402.21 EHU00093.1 - 0.081 12.9 0.0 0.26 11.3 0.0 1.9 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Baseplate_J PF04865.14 EHU00094.1 - 2.4e-57 194.0 6.5 2.4e-57 194.0 6.5 1.4 2 0 0 2 2 2 1 Baseplate J-like protein bPH_2 PF03703.14 EHU00094.1 - 0.08 13.1 0.0 0.43 10.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial PH domain HTH_Tnp_1 PF01527.20 EHU00095.1 - 8e-10 38.9 0.0 8.6e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU00095.1 - 0.019 14.8 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU00095.1 - 0.025 14.7 0.0 0.044 13.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU00095.1 - 0.052 13.6 0.0 0.06 13.4 0.0 1.3 1 1 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHU00096.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHU00097.1 - 1.4e-97 326.6 4.4 3.8e-97 325.2 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU00097.1 - 3e-16 59.4 0.1 1.3e-15 57.3 0.1 2.3 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU00097.1 - 1.4e-14 54.2 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU00097.1 - 6.2e-10 39.7 8.7 1.3e-09 38.6 8.7 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Phage_HK97_TLTM PF06120.11 EHU00097.1 - 0.015 14.5 0.7 0.028 13.6 0.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHU00097.1 - 0.03 14.6 4.4 0.13 12.6 0.7 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain UME PF08064.13 EHU00097.1 - 0.035 14.0 0.3 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain FUSC PF04632.12 EHU00097.1 - 0.037 12.6 7.0 0.06 11.9 7.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tho2 PF11262.8 EHU00097.1 - 0.039 13.2 0.5 0.064 12.5 0.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FAM184 PF15665.5 EHU00097.1 - 0.071 12.9 7.6 0.11 12.2 7.6 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Exonuc_VII_L PF02601.15 EHU00097.1 - 0.092 12.3 2.4 0.1 12.2 0.9 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit HalX PF08663.10 EHU00097.1 - 0.11 12.8 2.3 0.29 11.5 2.3 1.7 1 0 0 1 1 1 0 HalX domain ERM PF00769.19 EHU00097.1 - 0.17 11.7 10.2 0.28 11.0 10.2 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family LXG PF04740.12 EHU00097.1 - 0.35 10.5 2.5 1 9.0 0.3 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily Zn-ribbon_8 PF09723.10 EHU00097.1 - 0.46 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DHR10 PF18595.1 EHU00097.1 - 0.52 10.4 10.4 0.91 9.6 10.4 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF1192 PF06698.11 EHU00097.1 - 1.1 9.4 6.1 4 7.6 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHU00097.1 - 1.1 8.5 2.7 1.6 7.9 2.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHU00097.1 - 2.3 7.7 7.2 5.2 6.6 7.2 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 CREPT PF16566.5 EHU00097.1 - 7.3 6.8 8.2 3.4 7.8 5.1 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour SlyX PF04102.12 EHU00097.1 - 9 7.0 8.8 16 6.2 2.2 3.0 1 1 1 2 2 2 0 SlyX DDE_3 PF13358.6 EHU00098.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHU00098.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHU00098.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHU00098.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHU00098.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHU00098.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHU00098.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHU00098.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 HD_2 PF12917.7 EHU00100.1 - 7.4e-06 25.8 0.1 1.4e-05 25.0 0.1 1.6 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme HD_3 PF13023.6 EHU00100.1 - 0.0016 18.4 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 HD domain MAP65_ASE1 PF03999.12 EHU00102.1 - 0.14 10.8 0.2 0.18 10.5 0.2 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF2786 PF10979.8 EHU00103.1 - 1.6e-13 50.3 5.0 3.6e-13 49.2 5.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2786) Histone_HNS PF00816.21 EHU00103.1 - 0.068 14.0 0.5 0.16 12.8 0.0 1.9 2 0 0 2 2 2 0 H-NS histone family PerC PF06069.11 EHU00105.1 - 0.00092 19.4 1.5 0.00098 19.3 1.5 1.0 1 0 0 1 1 1 1 PerC transcriptional activator AAA_22 PF13401.6 EHU00108.1 - 2.2e-20 73.4 0.0 6.1e-20 71.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 EHU00108.1 - 6e-07 29.1 0.0 5.8e-06 25.8 0.0 2.1 1 1 0 1 1 1 1 Bacterial TniB protein AAA_30 PF13604.6 EHU00108.1 - 8.4e-07 28.9 0.0 1.7e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain HTH_38 PF13936.6 EHU00108.1 - 0.00055 19.6 0.0 0.0018 18.0 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 EHU00108.1 - 0.00066 19.7 0.1 0.0023 18.0 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix HTH_31 PF13560.6 EHU00108.1 - 0.00073 19.8 0.0 0.0039 17.5 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain AAA_16 PF13191.6 EHU00108.1 - 0.0017 18.7 0.0 0.008 16.6 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain HTH_26 PF13443.6 EHU00108.1 - 0.0062 16.9 0.0 0.029 14.8 0.0 2.1 2 0 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 EHU00108.1 - 0.013 15.0 0.0 0.23 11.1 0.0 2.6 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding AAA_14 PF13173.6 EHU00108.1 - 0.016 15.2 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EHU00108.1 - 0.017 14.8 0.0 0.024 14.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EHU00108.1 - 0.019 14.9 0.0 0.054 13.4 0.0 1.7 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea HTH_23 PF13384.6 EHU00108.1 - 0.028 14.2 0.1 0.14 12.0 0.0 2.2 3 0 0 3 3 3 0 Homeodomain-like domain KorB PF08535.10 EHU00108.1 - 0.03 14.3 0.0 0.09 12.8 0.0 1.9 1 0 0 1 1 1 0 KorB domain HTH_8 PF02954.19 EHU00108.1 - 0.04 13.7 0.0 0.13 12.0 0.0 1.9 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family AAA_19 PF13245.6 EHU00108.1 - 0.042 14.2 0.0 1.5 9.2 0.0 2.3 1 1 0 1 1 1 0 AAA domain HTH_19 PF12844.7 EHU00108.1 - 0.072 13.1 0.0 0.42 10.7 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain AAA_7 PF12775.7 EHU00108.1 - 0.095 12.2 0.0 0.27 10.7 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region NB-ARC PF00931.22 EHU00108.1 - 0.12 11.5 0.0 0.34 10.1 0.0 1.7 1 1 0 1 1 1 0 NB-ARC domain rve PF00665.26 EHU00109.1 - 3.2e-16 59.6 0.0 1.5e-15 57.4 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Mu-transpos_C PF09299.11 EHU00109.1 - 5.4e-14 51.9 0.0 1e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Mu transposase, C-terminal rve_3 PF13683.6 EHU00109.1 - 7.5e-05 22.4 2.2 0.2 11.5 0.0 3.5 4 0 0 4 4 4 2 Integrase core domain DDE_2 PF02914.15 EHU00109.1 - 0.00031 20.6 0.0 0.00073 19.3 0.0 1.6 1 1 0 1 1 1 1 Bacteriophage Mu transposase Glyco_transf_8 PF01501.20 EHU00110.1 - 1.6e-10 41.0 0.1 2.1e-10 40.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 FliN_N PF16973.5 EHU00110.1 - 0.82 9.6 2.8 1.1 9.2 0.1 2.4 2 1 1 3 3 3 0 Flagellar motor switch protein FliN N-terminal GFO_IDH_MocA_C PF02894.17 EHU00111.1 - 7.2e-10 38.9 0.0 1.2e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.22 EHU00112.1 - 6.1e-13 49.7 0.1 7.3e-13 49.4 0.1 1.1 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EHU00112.1 - 0.00085 20.0 0.0 0.00097 19.8 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EHU00112.1 - 0.0056 16.9 0.1 0.0086 16.3 0.1 1.2 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DUF2827 PF10933.8 EHU00112.1 - 0.048 12.3 0.0 0.059 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2827) UDPG_MGDP_dh_N PF03721.14 EHU00112.1 - 0.095 12.3 0.4 0.17 11.4 0.4 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF5045 PF16464.5 EHU00113.1 - 0.013 15.8 0.0 0.016 15.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5045) NapD PF03927.13 EHU00113.1 - 0.17 12.0 0.1 0.4 10.8 0.1 1.7 1 1 1 2 2 2 0 NapD protein T6SS_HCP PF05638.12 EHU00116.1 - 3.1e-13 50.2 0.1 3.6e-13 50.0 0.1 1.0 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp Bac_luciferase PF00296.20 EHU00117.1 - 2.2e-23 83.2 0.6 3.1e-23 82.7 0.6 1.3 1 0 0 1 1 1 1 Luciferase-like monooxygenase ApbA PF02558.16 EHU00118.1 - 1.8e-33 115.4 1.2 2.1e-33 115.1 0.4 1.5 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 EHU00118.1 - 1.1e-19 70.9 0.0 1.6e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Peripla_BP_3 PF13377.6 EHU00119.1 - 1.4e-37 129.6 4.9 2.4e-37 128.8 1.0 2.2 2 0 0 2 2 2 1 Periplasmic binding protein-like domain LacI PF00356.21 EHU00119.1 - 3.2e-23 81.2 0.3 6e-22 77.2 0.3 2.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family Peripla_BP_1 PF00532.21 EHU00119.1 - 1.1e-21 77.5 2.3 1.7e-21 76.9 2.3 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 EHU00119.1 - 1.4e-17 64.2 0.3 2.3e-17 63.4 0.3 1.4 1 0 0 1 1 1 1 Periplasmic binding protein domain HTH_31 PF13560.6 EHU00119.1 - 0.00053 20.3 1.4 0.0019 18.5 0.2 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_10 PF04967.12 EHU00119.1 - 0.00063 19.5 0.2 0.0024 17.6 0.0 2.1 2 0 0 2 2 2 1 HTH DNA binding domain HTH_Crp_2 PF13545.6 EHU00119.1 - 0.0039 17.1 0.1 0.022 14.7 0.1 2.3 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_3 PF01381.22 EHU00119.1 - 0.0054 16.8 0.1 0.014 15.4 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix HTH_DeoR PF08220.12 EHU00119.1 - 0.0072 16.0 1.2 1.3 8.8 0.1 3.2 3 1 0 3 3 3 1 DeoR-like helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 EHU00119.1 - 0.0077 15.6 0.2 0.028 13.8 0.2 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_AraC PF00165.23 EHU00119.1 - 0.0077 16.3 0.0 0.021 14.9 0.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_23 PF13384.6 EHU00119.1 - 0.012 15.4 0.2 0.045 13.6 0.0 2.1 2 0 0 2 2 1 0 Homeodomain-like domain HTH_29 PF13551.6 EHU00119.1 - 0.025 14.6 0.0 0.075 13.1 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn helix DUF3175 PF11373.8 EHU00119.1 - 0.074 13.2 0.3 0.23 11.6 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3175) HTH_38 PF13936.6 EHU00119.1 - 0.14 11.9 0.3 0.66 9.8 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain ParD PF09386.10 EHU00119.1 - 0.78 10.2 3.8 3.5 8.1 0.5 3.0 3 0 0 3 3 3 0 Antitoxin ParD DUF496 PF04363.12 EHU00120.1 - 3.8e-45 151.9 9.0 4.3e-45 151.7 9.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF496) ELP6 PF09807.9 EHU00120.1 - 0.042 13.2 0.1 0.044 13.2 0.1 1.1 1 0 0 1 1 1 0 Elongation complex protein 6 FUSC_2 PF13515.6 EHU00121.1 - 4.8e-14 52.6 14.8 7.6e-14 51.9 14.8 1.3 1 0 0 1 1 1 1 Fusaric acid resistance protein-like FUSC PF04632.12 EHU00121.1 - 1.7e-13 50.0 6.6 2.1e-13 49.8 6.6 1.0 1 0 0 1 1 1 1 Fusaric acid resistance protein family Peptidase_S11 PF00768.20 EHU00122.1 - 3.6e-90 301.6 0.0 4.7e-90 301.2 0.0 1.1 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase PBP5_C PF07943.13 EHU00122.1 - 5.8e-21 74.5 0.1 1e-20 73.7 0.1 1.4 1 0 0 1 1 1 1 Penicillin-binding protein 5, C-terminal domain Beta-lactamase2 PF13354.6 EHU00122.1 - 2.6e-13 50.0 0.0 3.8e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase enzyme family Beta-lactamase PF00144.24 EHU00122.1 - 0.0057 15.9 0.7 0.067 12.4 0.1 2.2 2 1 0 2 2 2 1 Beta-lactamase Exonuc_X-T_C PF08411.10 EHU00123.1 - 1.1e-104 349.4 0.0 1.4e-104 349.0 0.0 1.1 1 0 0 1 1 1 1 Exonuclease C-terminal RNase_T PF00929.24 EHU00123.1 - 2.2e-26 93.4 0.0 4e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 Exonuclease GntP_permease PF02447.16 EHU00124.1 - 2.3e-133 445.1 43.6 2.7e-133 444.9 43.6 1.0 1 0 0 1 1 1 1 GntP family permease CitMHS PF03600.16 EHU00124.1 - 1.4e-15 57.3 44.9 4.5e-15 55.6 44.9 1.8 1 1 0 1 1 1 1 Citrate transporter Na_H_antiport_2 PF13726.6 EHU00124.1 - 0.18 12.0 23.4 0.4 10.9 12.2 3.6 2 1 0 2 2 2 0 Na+-H+ antiporter family AP_endonuc_2 PF01261.24 EHU00125.1 - 4e-36 124.4 0.1 4.9e-36 124.2 0.1 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Aldolase_II PF00596.21 EHU00126.1 - 7e-43 146.7 0.0 8.2e-43 146.5 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain SBD_N PF07005.11 EHU00127.1 - 1.4e-69 234.3 0.0 2.3e-69 233.6 0.0 1.4 1 0 0 1 1 1 1 Sugar-binding N-terminal domain NBD_C PF17042.5 EHU00127.1 - 1.3e-41 142.9 0.5 8.7e-41 140.3 0.0 2.1 2 0 0 2 2 2 1 Nucleotide-binding C-terminal domain ChW PF07538.11 EHU00127.1 - 0.018 15.0 0.1 0.04 13.9 0.1 1.6 1 0 0 1 1 1 0 Clostridial hydrophobic W NAD_binding_2 PF03446.15 EHU00128.1 - 1.5e-38 132.4 2.5 2.4e-38 131.8 2.5 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EHU00128.1 - 9.5e-34 116.3 2.1 1e-33 116.2 0.4 1.9 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 3HCDH_N PF02737.18 EHU00128.1 - 1.8e-05 24.7 0.4 4e-05 23.6 0.1 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EHU00128.1 - 0.00017 22.1 0.4 0.001 19.6 0.1 2.2 1 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 EHU00128.1 - 0.0011 18.4 0.8 0.0014 17.9 0.6 1.6 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 EHU00128.1 - 0.0089 16.3 0.0 0.017 15.3 0.0 1.6 1 1 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.19 EHU00128.1 - 0.045 13.1 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EHU00128.1 - 0.051 13.2 0.0 0.14 11.8 0.0 1.7 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DeoRC PF00455.22 EHU00129.1 - 3.6e-50 170.0 0.0 6.4e-50 169.2 0.0 1.3 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 EHU00129.1 - 3.1e-18 65.3 0.4 6.4e-18 64.2 0.4 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 EHU00129.1 - 1.1e-10 41.2 0.1 2e-10 40.4 0.1 1.4 1 0 0 1 1 1 1 HTH domain HTH_24 PF13412.6 EHU00129.1 - 1.5e-05 24.4 0.1 0.00012 21.6 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding GntR PF00392.21 EHU00129.1 - 4.7e-05 23.0 0.3 0.0001 21.9 0.3 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_23 PF13384.6 EHU00129.1 - 0.00015 21.5 0.1 0.00031 20.4 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain MarR PF01047.22 EHU00129.1 - 0.00016 21.6 0.1 0.00043 20.2 0.1 1.7 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 EHU00129.1 - 0.00022 21.5 0.1 0.00045 20.5 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulator HTH_28 PF13518.6 EHU00129.1 - 0.00069 19.7 0.0 0.0018 18.4 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 EHU00129.1 - 0.00069 19.5 0.4 0.0017 18.2 0.4 1.6 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 EHU00129.1 - 0.0016 18.5 2.2 0.0024 17.9 0.1 2.4 3 0 0 3 3 3 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 EHU00129.1 - 0.0031 17.0 0.4 0.0073 15.8 0.4 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_IclR PF09339.10 EHU00129.1 - 0.0034 17.1 0.1 0.0075 16.0 0.1 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain PaaX PF07848.12 EHU00129.1 - 0.0037 17.5 0.3 0.0071 16.5 0.3 1.4 1 0 0 1 1 1 1 PaaX-like protein HTH_AsnC-type PF13404.6 EHU00129.1 - 0.0039 17.0 0.1 0.011 15.6 0.1 1.8 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_Mga PF08280.11 EHU00129.1 - 0.004 17.1 0.0 0.008 16.2 0.0 1.4 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain AbiEi_4 PF13338.6 EHU00129.1 - 0.0059 16.7 0.0 0.35 11.1 0.0 2.7 2 0 0 2 2 2 1 Transcriptional regulator, AbiEi antitoxin TrmB PF01978.19 EHU00129.1 - 0.0065 16.3 0.1 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.20 EHU00129.1 - 0.01 15.7 0.8 0.032 14.1 0.1 2.2 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Fe_dep_repress PF01325.19 EHU00129.1 - 0.012 15.8 0.1 0.026 14.7 0.1 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_38 PF13936.6 EHU00129.1 - 0.021 14.6 0.0 0.14 11.9 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 EHU00129.1 - 0.034 13.5 0.1 0.084 12.3 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DDRGK PF09756.9 EHU00129.1 - 0.038 13.6 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 DDRGK domain HTH_psq PF05225.16 EHU00129.1 - 0.068 12.9 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 helix-turn-helix, Psq domain DUF977 PF06163.11 EHU00129.1 - 0.12 12.3 0.1 0.27 11.2 0.1 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) Mga PF05043.13 EHU00129.1 - 0.21 12.2 0.0 0.79 10.3 0.0 1.9 2 0 0 2 2 2 0 Mga helix-turn-helix domain AA_permease_2 PF13520.6 EHU00130.1 - 1.1e-34 120.1 36.9 1.3e-34 119.7 36.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EHU00130.1 - 2.5e-32 112.1 37.1 3e-32 111.8 37.1 1.1 1 0 0 1 1 1 1 Amino acid permease Gln-synt_C PF00120.24 EHU00132.1 - 7.3e-84 281.7 0.0 8.9e-46 156.5 0.0 2.1 1 1 1 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 EHU00132.1 - 2.2e-05 24.2 0.0 5.5e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Glutamine synthetase N-terminal domain Peptidase_C26 PF07722.13 EHU00133.1 - 2.2e-61 207.4 0.5 2.5e-61 207.2 0.5 1.0 1 0 0 1 1 1 1 Peptidase C26 GATase PF00117.28 EHU00133.1 - 3.2e-13 49.9 0.0 6.1e-13 49.0 0.0 1.6 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Cupin_2 PF07883.11 EHU00134.1 - 3e-17 62.1 0.1 4.9e-17 61.4 0.1 1.3 1 0 0 1 1 1 1 Cupin domain HTH_3 PF01381.22 EHU00134.1 - 3.6e-13 49.4 0.1 5.2e-13 48.8 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EHU00134.1 - 1.6e-11 44.4 0.2 3.4e-11 43.3 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 EHU00134.1 - 5.8e-09 35.8 0.0 9.6e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain MqsA_antitoxin PF15731.5 EHU00134.1 - 0.00019 21.6 0.0 0.00027 21.0 0.0 1.2 1 0 0 1 1 1 1 Antitoxin component of bacterial toxin-antitoxin system, MqsA HTH_37 PF13744.6 EHU00134.1 - 0.00019 21.3 0.1 0.00064 19.6 0.1 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_26 PF13443.6 EHU00134.1 - 0.00063 20.1 0.1 0.002 18.5 0.0 1.8 2 0 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 EHU00134.1 - 0.0032 17.3 0.1 0.0057 16.5 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain AraC_binding_2 PF14525.6 EHU00134.1 - 0.0076 15.9 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 AraC-binding-like domain AraC_binding PF02311.19 EHU00134.1 - 0.013 15.4 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 AraC-like ligand binding domain Death PF00531.22 EHU00134.1 - 0.03 14.5 0.0 0.05 13.8 0.0 1.3 1 0 0 1 1 1 0 Death domain CENP-C_C PF11699.8 EHU00134.1 - 0.072 13.3 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 Mif2/CENP-C like Cupin_3 PF05899.12 EHU00134.1 - 0.082 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DAO PF01266.24 EHU00135.1 - 1e-46 160.2 0.1 1.2e-46 160.0 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EHU00135.1 - 3.1e-06 26.7 0.3 6e-06 25.7 0.2 1.6 1 1 1 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EHU00135.1 - 0.00053 20.2 1.4 0.0023 18.1 1.3 2.2 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EHU00135.1 - 0.00089 18.6 0.1 0.0015 17.9 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 EHU00135.1 - 0.0044 16.2 0.5 0.0078 15.3 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EHU00135.1 - 0.0076 15.5 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EHU00135.1 - 0.0078 15.9 0.2 1.1 8.9 0.1 2.2 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 EHU00135.1 - 0.091 13.3 0.2 0.22 12.1 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 EHU00135.1 - 0.13 11.8 0.2 0.2 11.2 0.2 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Epimerase PF01370.21 EHU00136.1 - 2.6e-11 43.5 0.0 1.6e-10 40.9 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family UDPG_MGDP_dh_N PF03721.14 EHU00136.1 - 0.00014 21.5 0.1 0.0013 18.4 0.1 2.1 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_10 PF13460.6 EHU00136.1 - 0.00017 21.5 0.0 0.00018 21.4 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EHU00136.1 - 0.00025 20.2 0.0 0.0005 19.3 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_2 PF03446.15 EHU00136.1 - 0.00026 21.2 0.0 0.0004 20.6 0.0 1.4 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 EHU00136.1 - 0.0018 18.5 0.0 0.0027 18.0 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.19 EHU00136.1 - 0.003 16.6 0.0 0.0039 16.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.18 EHU00136.1 - 0.018 14.9 0.1 0.032 14.1 0.1 1.5 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EHU00136.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HisG PF01634.18 EHU00137.1 - 9.2e-48 162.2 0.0 1.2e-47 161.8 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 EHU00137.1 - 2.4e-23 82.0 0.0 5.1e-23 81.0 0.0 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain Toprim_3 PF13362.6 EHU00137.1 - 0.0039 17.5 0.0 0.16 12.3 0.0 2.3 2 0 0 2 2 2 1 Toprim domain Histidinol_dh PF00815.20 EHU00138.1 - 7.4e-164 545.6 0.6 8.3e-164 545.4 0.6 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase AIRS_C PF02769.22 EHU00138.1 - 0.076 13.1 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 AIR synthase related protein, C-terminal domain Aminotran_1_2 PF00155.21 EHU00139.1 - 7.4e-59 199.7 0.0 9e-59 199.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EHU00139.1 - 0.0024 16.9 0.0 0.009 15.0 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_MocR PF12897.7 EHU00139.1 - 0.058 12.2 0.0 0.08 11.7 0.0 1.1 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Cys_Met_Meta_PP PF01053.20 EHU00139.1 - 0.065 11.7 0.0 0.096 11.2 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme NT5C PF06941.12 EHU00139.1 - 0.095 12.6 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) IGPD PF00475.18 EHU00140.1 - 9.6e-64 214.0 0.5 1.5e-63 213.4 0.5 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Hydrolase_like PF13242.6 EHU00140.1 - 7.1e-08 32.4 0.0 1.4e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 EHU00140.1 - 7.4e-07 29.4 0.0 0.00012 22.2 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PNK3P PF08645.11 EHU00140.1 - 5.5e-06 26.2 0.0 1.5e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 Polynucleotide kinase 3 phosphatase Hydrolase PF00702.26 EHU00140.1 - 0.00051 20.4 0.0 0.011 16.1 0.0 2.5 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EHU00140.1 - 0.0031 17.9 0.0 0.012 16.0 0.0 2.0 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase GATase PF00117.28 EHU00141.1 - 1.1e-18 67.8 0.0 1.2e-18 67.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 EHU00141.1 - 2.6e-07 30.7 0.0 0.0003 20.7 0.0 2.0 2 0 0 2 2 2 2 SNO glutamine amidotransferase family Peptidase_C26 PF07722.13 EHU00141.1 - 1.2e-05 25.2 0.4 0.01 15.6 0.0 2.2 2 0 0 2 2 2 2 Peptidase C26 GATase_3 PF07685.14 EHU00141.1 - 5.2e-05 22.9 0.0 7.4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain His_biosynth PF00977.21 EHU00142.1 - 1.8e-75 253.3 0.2 2e-75 253.2 0.2 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.17 EHU00142.1 - 1.2e-05 24.6 0.0 0.091 11.8 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) Trp_syntA PF00290.20 EHU00142.1 - 2e-05 23.6 0.3 0.00023 20.1 0.0 2.1 2 0 0 2 2 2 1 Tryptophan synthase alpha chain NanE PF04131.14 EHU00142.1 - 3.4e-05 23.1 0.5 0.00016 20.9 0.0 2.2 3 0 0 3 3 3 1 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.15 EHU00142.1 - 5.3e-05 22.8 2.2 0.0031 16.9 0.2 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase IGPS PF00218.21 EHU00142.1 - 5.8e-05 22.4 0.2 0.22 10.6 0.0 2.2 2 0 0 2 2 2 2 Indole-3-glycerol phosphate synthase PcrB PF01884.17 EHU00142.1 - 0.00022 20.8 0.2 0.0017 17.9 0.0 2.0 2 0 0 2 2 2 1 PcrB family IMPDH PF00478.25 EHU00142.1 - 0.013 14.6 0.4 0.077 12.0 0.1 2.0 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EHU00142.1 - 0.021 13.9 3.6 2.2 7.2 0.3 2.5 2 1 0 3 3 3 0 FMN-dependent dehydrogenase DHO_dh PF01180.21 EHU00142.1 - 0.039 13.2 0.0 0.077 12.2 0.0 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase TMP-TENI PF02581.17 EHU00142.1 - 0.043 13.2 0.4 3 7.1 0.1 2.2 2 0 0 2 2 2 0 Thiamine monophosphate synthase G3P_antiterm PF04309.12 EHU00142.1 - 0.13 11.7 0.3 0.27 10.6 0.1 1.6 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator His_biosynth PF00977.21 EHU00143.1 - 9.4e-77 257.5 0.6 1.1e-76 257.4 0.6 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.17 EHU00143.1 - 4.3e-07 29.3 0.2 0.00022 20.4 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) ThiG PF05690.14 EHU00143.1 - 1.1e-06 28.2 0.5 0.00016 21.1 0.1 2.1 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG NMO PF03060.15 EHU00143.1 - 1.3e-05 24.8 0.2 0.021 14.2 0.0 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase TMP-TENI PF02581.17 EHU00143.1 - 0.00022 20.6 0.0 0.0096 15.3 0.0 2.3 2 0 0 2 2 2 1 Thiamine monophosphate synthase FMN_dh PF01070.18 EHU00143.1 - 0.00088 18.4 0.1 0.29 10.1 0.0 2.1 2 0 0 2 2 2 2 FMN-dependent dehydrogenase Oxidored_FMN PF00724.20 EHU00143.1 - 0.02 14.2 0.0 0.28 10.4 0.0 2.1 2 0 0 2 2 2 0 NADH:flavin oxidoreductase / NADH oxidase family G3P_antiterm PF04309.12 EHU00143.1 - 0.026 13.9 0.0 0.25 10.7 0.0 2.1 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator NanE PF04131.14 EHU00143.1 - 0.042 13.0 0.0 0.11 11.7 0.0 1.8 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase PcrB PF01884.17 EHU00143.1 - 0.11 12.0 0.0 0.43 10.0 0.0 1.9 2 0 0 2 2 2 0 PcrB family IMPDH PF00478.25 EHU00143.1 - 0.12 11.4 0.2 0.55 9.2 0.0 1.9 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain PRA-CH PF01502.18 EHU00144.1 - 6.9e-31 105.9 0.0 1.2e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 EHU00144.1 - 2.9e-17 62.9 0.2 3.8e-17 62.5 0.2 1.2 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 EHU00144.1 - 0.085 13.1 0.2 0.13 12.4 0.2 1.4 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain tRNA_edit PF04073.15 EHU00145.1 - 1.7e-26 92.7 0.1 2e-26 92.5 0.1 1.1 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain TAL_effector PF03377.13 EHU00145.1 - 0.018 15.3 0.0 0.071 13.4 0.0 2.1 1 0 0 1 1 1 0 TAL effector repeat SBP_bac_3 PF00497.20 EHU00146.1 - 2.3e-19 69.7 0.0 2.7e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 SBP_bac_3 PF00497.20 EHU00147.1 - 8e-27 94.1 0.0 8.8e-27 94.0 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.11 EHU00147.1 - 0.00057 19.9 0.0 0.00075 19.5 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 EHU00147.1 - 0.015 14.9 0.3 2.3 7.7 0.1 2.6 3 0 0 3 3 3 0 ABC transporter, phosphonate, periplasmic substrate-binding protein DDE_3 PF13358.6 EHU00148.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHU00148.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHU00148.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHU00148.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHU00148.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHU00148.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHU00148.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHU00148.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 Wzy_C PF04932.15 EHU00149.1 - 2.1e-10 40.4 1.3 2.1e-10 40.4 1.3 4.0 1 1 3 4 4 4 2 O-Antigen ligase Glycos_transf_1 PF00534.20 EHU00150.1 - 4.5e-25 88.2 0.0 8.7e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EHU00150.1 - 1.9e-21 76.9 0.0 3.7e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EHU00150.1 - 3e-06 27.3 0.3 7.9e-06 26.0 0.3 1.7 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 EHU00150.1 - 0.0013 19.1 0.0 0.0031 17.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EHU00150.1 - 0.029 14.8 0.0 0.047 14.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain DUF2451 PF10474.9 EHU00150.1 - 0.071 12.9 0.1 0.11 12.3 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) AstE_AspA PF04952.14 EHU00151.1 - 1.4e-19 70.3 0.0 4.4e-18 65.4 0.0 2.3 1 1 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Peptidase_M14 PF00246.24 EHU00151.1 - 0.0049 16.7 0.0 0.0095 15.8 0.0 1.4 1 1 0 1 1 1 1 Zinc carboxypeptidase Wzz PF02706.15 EHU00152.1 - 1.2e-13 51.2 4.7 1.6e-13 50.8 0.4 2.8 2 0 0 2 2 2 1 Chain length determinant protein GNVR PF13807.6 EHU00152.1 - 4.8e-06 26.4 0.0 4.8e-06 26.4 0.0 3.2 3 0 0 3 3 3 1 G-rich domain on putative tyrosine kinase Sulf_transp PF04143.14 EHU00152.1 - 0.007 16.0 0.2 0.058 12.9 0.1 2.0 2 0 0 2 2 2 1 Sulphur transport Peptidase_A8 PF01252.18 EHU00152.1 - 0.021 15.1 0.6 0.48 10.7 0.2 2.3 2 0 0 2 2 2 0 Signal peptidase (SPase) II DUF1275 PF06912.11 EHU00152.1 - 0.029 14.3 0.3 4 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1275) DUF554 PF04474.12 EHU00152.1 - 0.072 12.5 0.8 0.2 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF554) LapA_dom PF06305.11 EHU00152.1 - 2.8 7.8 5.9 2.7 7.8 0.3 2.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain 6PGD PF00393.19 EHU00153.1 - 2.1e-130 434.3 0.1 3.1e-130 433.7 0.1 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EHU00153.1 - 7.2e-53 179.0 0.0 1.1e-52 178.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EHU00153.1 - 0.0017 18.4 0.0 0.0046 17.0 0.0 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 EHU00153.1 - 0.0023 18.5 0.0 0.0059 17.2 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 EHU00153.1 - 0.016 15.1 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EHU00153.1 - 0.024 14.0 0.1 0.049 13.0 0.0 1.6 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_11 PF14833.6 EHU00153.1 - 0.04 14.2 0.1 0.095 12.9 0.1 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase IlvN PF07991.12 EHU00153.1 - 0.1 12.1 0.1 1.3 8.6 0.0 2.6 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain GDP_Man_Dehyd PF16363.5 EHU00154.1 - 1.1e-54 186.1 0.0 1.3e-54 185.8 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EHU00154.1 - 2.2e-51 174.6 0.0 2.7e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EHU00154.1 - 7.4e-15 54.8 0.1 2.7e-13 49.7 0.1 2.7 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EHU00154.1 - 3.8e-14 52.4 0.3 6.5e-14 51.6 0.3 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EHU00154.1 - 2.2e-08 33.6 0.1 7.9e-07 28.5 0.1 2.2 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EHU00154.1 - 1e-05 25.5 0.0 1.7e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EHU00154.1 - 0.00022 20.7 0.0 0.00047 19.7 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EHU00154.1 - 0.00022 21.2 0.0 0.00042 20.3 0.0 1.3 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 EHU00154.1 - 0.00029 20.0 0.0 0.00053 19.2 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 EHU00154.1 - 0.0061 16.2 0.0 0.049 13.2 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family Glycos_transf_1 PF00534.20 EHU00155.1 - 1.4e-30 106.1 0.3 2.3e-30 105.4 0.3 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EHU00155.1 - 6.4e-21 75.2 0.0 1.1e-20 74.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 LIAS_N PF16881.5 EHU00155.1 - 0.13 12.7 0.0 31 5.1 0.0 2.5 2 0 0 2 2 2 0 N-terminal domain of lipoyl synthase of Radical_SAM family Glycos_transf_2 PF00535.26 EHU00157.1 - 3.2e-17 62.9 0.0 5.1e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 EHU00157.1 - 2.4e-08 33.8 0.1 2e-07 30.8 0.1 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 EHU00157.1 - 0.15 11.9 0.0 0.24 11.3 0.0 1.5 1 1 0 1 1 1 0 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EHU00158.1 - 1.9e-15 57.1 0.1 2.7e-15 56.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EHU00158.1 - 5.3e-07 29.8 0.0 8.5e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EHU00158.1 - 0.0099 15.8 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Polysacc_synt PF01943.17 EHU00159.1 - 7.8e-13 48.4 23.9 7.8e-13 48.4 23.9 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein Polysacc_synt_C PF14667.6 EHU00159.1 - 8.4 6.4 51.0 0.041 13.9 23.0 4.5 2 1 4 6 6 6 0 Polysaccharide biosynthesis C-terminal domain DegT_DnrJ_EryC1 PF01041.17 EHU00160.1 - 8.7e-108 360.8 0.0 9.9e-108 360.7 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EHU00160.1 - 6.2e-09 35.5 0.0 1.3e-08 34.4 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EHU00160.1 - 4.7e-07 29.1 0.0 8.4e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Chalcone_N PF18232.1 EHU00160.1 - 0.012 16.0 0.2 0.027 14.9 0.2 1.6 1 0 0 1 1 1 0 Chalcone isomerase N-terminal domain Formyl_trans_N PF00551.19 EHU00161.1 - 1.9e-16 60.3 0.0 4.7e-16 59.1 0.0 1.7 2 0 0 2 2 2 1 Formyl transferase Ank_5 PF13857.6 EHU00161.1 - 1.5e-09 37.9 0.0 9.7e-05 22.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EHU00161.1 - 1.3e-08 35.2 0.0 0.00044 20.8 0.0 3.8 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EHU00161.1 - 4e-05 24.1 0.1 0.00047 20.7 0.1 2.5 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EHU00161.1 - 0.0021 18.4 0.0 0.013 15.9 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Formyl_trans_C PF02911.18 EHU00161.1 - 0.0049 17.1 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain N_formyltrans_C PF18216.1 EHU00161.1 - 0.06 13.0 0.2 21 4.9 0.0 3.4 3 0 0 3 3 3 0 N-formyltransferase dimerization C-terminal domain NTP_transferase PF00483.23 EHU00162.1 - 8.1e-71 238.5 0.0 9.5e-71 238.3 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EHU00162.1 - 5.1e-10 39.9 0.0 6.8e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 EHU00162.1 - 0.0091 15.8 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GDP_Man_Dehyd PF16363.5 EHU00163.1 - 8.3e-98 327.8 0.0 9.9e-98 327.6 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EHU00163.1 - 1.3e-72 244.1 0.0 1.7e-72 243.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EHU00163.1 - 6.9e-16 58.2 0.0 1.5e-15 57.1 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EHU00163.1 - 7e-15 54.8 0.0 1.2e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EHU00163.1 - 2.6e-13 49.7 0.0 3.9e-13 49.2 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EHU00163.1 - 5.8e-13 48.6 0.0 3.7e-11 42.7 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 EHU00163.1 - 1.9e-05 24.2 0.1 0.0076 15.7 0.1 2.4 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 EHU00163.1 - 0.00022 21.2 0.0 0.00048 20.1 0.0 1.5 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EHU00163.1 - 0.018 15.3 0.1 0.03 14.6 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Gp_dh_N PF00044.24 EHU00163.1 - 0.025 14.9 0.1 0.073 13.4 0.0 1.9 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 EHU00163.1 - 0.045 13.7 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Ldh_1_N PF00056.23 EHU00163.1 - 0.14 12.3 0.1 0.28 11.3 0.1 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DDE_Tnp_IS1 PF03400.13 EHU00164.1 - 2.1e-36 125.1 0.4 2.3e-36 125.0 0.4 1.0 1 0 0 1 1 1 1 IS1 transposase HTH_Tnp_IS1 PF12759.7 EHU00165.1 - 2.6e-18 65.3 1.0 2.8e-18 65.2 1.0 1.0 1 0 0 1 1 1 1 InsA C-terminal domain HTH_Tnp_ISL3 PF13542.6 EHU00165.1 - 0.035 13.5 0.0 0.035 13.5 0.0 1.0 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 EHU00165.1 - 0.11 12.3 0.0 0.11 12.3 0.0 1.0 1 0 0 1 1 1 0 Homeodomain-like domain DDE_3 PF13358.6 EHU00167.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHU00167.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHU00167.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHU00167.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHU00167.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHU00167.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHU00167.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHU00167.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 Glycos_transf_4 PF00953.21 EHU00168.1 - 1.3e-27 96.7 21.7 1.3e-27 96.7 21.7 1.4 2 0 0 2 2 2 1 Glycosyl transferase family 4 TRAM1 PF08390.11 EHU00168.1 - 0.13 11.9 0.5 0.35 10.6 0.1 1.8 2 0 0 2 2 2 0 TRAM1-like protein Epimerase PF01370.21 EHU00169.1 - 5.2e-60 202.9 0.0 6.2e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EHU00169.1 - 3.7e-58 197.5 0.0 4.7e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EHU00169.1 - 3.9e-18 65.4 0.0 5.5e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EHU00169.1 - 4.6e-16 58.8 0.0 3.1e-15 56.1 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EHU00169.1 - 3e-12 46.2 0.0 4.5e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 EHU00169.1 - 3e-08 33.5 0.0 2.1e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family KR PF08659.10 EHU00169.1 - 5.6e-08 32.9 0.0 8.6e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 EHU00169.1 - 1.2e-07 31.4 0.1 4e-07 29.7 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.6 EHU00169.1 - 4.8e-07 29.8 0.0 8e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EHU00169.1 - 1.3e-05 24.5 0.1 0.00014 21.1 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein TrkA_N PF02254.18 EHU00169.1 - 0.025 14.9 0.1 0.042 14.1 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain adh_short_C2 PF13561.6 EHU00169.1 - 0.069 12.7 0.0 0.13 11.8 0.1 1.5 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase UDPG_MGDP_dh_N PF03721.14 EHU00169.1 - 0.07 12.7 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NTP_transferase PF00483.23 EHU00170.1 - 1.4e-22 80.5 0.0 1.7e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EHU00170.1 - 7.1e-08 33.0 0.0 1e-07 32.5 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain PvlArgDC PF01862.16 EHU00170.1 - 0.023 14.5 0.0 0.053 13.3 0.0 1.6 2 0 0 2 2 2 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) Polysacc_synt_3 PF13440.6 EHU00171.1 - 1.2e-51 175.7 11.0 1.2e-51 175.7 11.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Polysacc_synt PF01943.17 EHU00171.1 - 2.7e-34 118.8 34.0 1.5e-32 113.1 13.6 2.1 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein Glycos_transf_1 PF00534.20 EHU00172.1 - 1.3e-36 125.7 0.0 2.3e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EHU00172.1 - 3.6e-28 98.7 0.1 2.1e-27 96.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EHU00172.1 - 8.2e-08 32.4 0.0 4.6e-05 23.5 0.0 2.9 2 1 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 EHU00172.1 - 0.00019 21.8 0.0 0.00043 20.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EHU00172.1 - 0.0033 17.9 0.0 0.17 12.3 0.0 2.6 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain PS_pyruv_trans PF04230.13 EHU00173.1 - 7e-36 124.6 0.1 8.6e-36 124.3 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide pyruvyl transferase DUF3748 PF12566.8 EHU00173.1 - 0.04 13.9 0.1 0.097 12.6 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3748) Head_binding PF09008.10 EHU00174.1 - 3.2e-15 56.4 0.0 9.4e-15 54.9 0.0 1.7 2 0 0 2 2 2 1 Head binding Pectate_lyase_3 PF12708.7 EHU00174.1 - 6.5e-05 22.9 1.1 0.00073 19.4 1.1 2.4 1 1 0 1 1 1 1 Pectate lyase superfamily protein Glycos_transf_1 PF00534.20 EHU00175.1 - 1.5e-35 122.3 0.0 2.4e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EHU00175.1 - 4.4e-30 104.8 0.0 6.8e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EHU00175.1 - 0.0041 17.5 0.0 0.011 16.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_2 PF00535.26 EHU00176.1 - 9.9e-30 103.6 0.5 1.5e-29 103.0 0.4 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EHU00176.1 - 3.6e-11 43.4 0.1 5.5e-11 42.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EHU00176.1 - 6.3e-10 39.0 0.6 1.4e-09 37.9 0.1 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 EHU00176.1 - 0.032 14.7 2.1 0.073 13.6 1.7 1.9 1 1 0 1 1 1 0 Glycosyl transferase family 2 LIDHydrolase PF10230.9 EHU00176.1 - 0.049 13.2 0.1 0.077 12.5 0.1 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Glyco_transf_21 PF13506.6 EHU00176.1 - 0.05 13.1 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EHU00177.1 - 2.6e-27 95.7 0.2 3.8e-27 95.1 0.2 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EHU00177.1 - 1.4e-13 51.3 0.0 1.9e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EHU00177.1 - 9.6e-13 48.2 0.8 1.7e-12 47.4 0.8 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EHU00177.1 - 0.01 15.7 0.1 0.025 14.5 0.1 1.5 1 1 0 1 1 1 0 Glycosyl transferase family group 2 EpsG PF14897.6 EHU00178.1 - 2.8e-35 122.2 42.5 3.8e-35 121.7 42.5 1.1 1 0 0 1 1 1 1 EpsG family ACR_tran PF00873.19 EHU00178.1 - 0.43 8.1 1.1 0.67 7.5 1.1 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family GNVR PF13807.6 EHU00179.1 - 2.5e-34 117.0 2.9 4.2e-34 116.3 1.7 2.1 2 0 0 2 2 1 1 G-rich domain on putative tyrosine kinase Wzz PF02706.15 EHU00179.1 - 1.4e-21 76.5 0.4 1.4e-21 76.5 0.4 2.5 3 0 0 3 3 2 1 Chain length determinant protein AAA_31 PF13614.6 EHU00179.1 - 8.1e-13 48.7 1.1 6.7e-12 45.7 0.0 2.9 2 2 1 3 3 3 1 AAA domain CbiA PF01656.23 EHU00179.1 - 9.1e-08 32.2 0.0 3.9e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 EHU00179.1 - 9.7e-07 28.8 0.6 0.037 13.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain ParA PF10609.9 EHU00179.1 - 1.2e-06 28.2 0.2 4e-06 26.4 0.2 1.8 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 EHU00179.1 - 3.2e-05 23.5 0.1 8.2e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ SRP54 PF00448.22 EHU00179.1 - 0.0018 17.9 0.1 0.037 13.7 0.0 2.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain MipZ PF09140.11 EHU00179.1 - 0.0024 17.2 0.0 0.0095 15.2 0.0 2.0 1 1 0 1 1 1 1 ATPase MipZ DUF4140 PF13600.6 EHU00179.1 - 0.0027 18.1 10.8 0.82 10.2 1.1 3.7 2 1 1 3 3 3 1 N-terminal domain of unknown function (DUF4140) DnaB_C PF03796.15 EHU00179.1 - 0.0033 16.8 0.0 0.0093 15.3 0.0 1.7 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 EHU00179.1 - 0.0033 17.2 0.0 0.0085 15.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein ArsA_ATPase PF02374.15 EHU00179.1 - 0.0069 15.6 4.6 4.6 6.3 0.1 4.2 3 1 1 4 4 4 1 Anion-transporting ATPase AAA_25 PF13481.6 EHU00179.1 - 0.0085 15.7 0.0 0.035 13.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain DUF3381 PF11861.8 EHU00179.1 - 0.011 15.6 0.3 0.011 15.6 0.3 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF3381) Occludin_ELL PF07303.13 EHU00179.1 - 0.011 16.4 6.8 0.048 14.4 0.9 2.7 3 0 0 3 3 2 0 Occludin homology domain Fer4_NifH PF00142.18 EHU00179.1 - 0.023 14.1 0.1 0.062 12.7 0.1 1.7 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family APS_kinase PF01583.20 EHU00179.1 - 0.093 12.6 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase Prefoldin_2 PF01920.20 EHU00179.1 - 0.16 11.9 9.6 0.12 12.4 0.7 3.3 3 0 0 3 3 3 0 Prefoldin subunit Wtap PF17098.5 EHU00179.1 - 0.21 11.5 9.7 0.74 9.7 9.2 2.0 1 1 0 1 1 1 0 WTAP/Mum2p family DASH_Spc34 PF08657.10 EHU00179.1 - 0.51 10.1 9.7 0.049 13.4 3.3 2.0 1 1 1 2 2 2 0 DASH complex subunit Spc34 HrpB7 PF09486.10 EHU00179.1 - 1.8 8.9 6.9 3.6 8.0 6.9 1.5 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) T2SSM PF04612.12 EHU00179.1 - 4.2 7.4 13.9 0.62 10.1 0.1 3.5 2 1 0 3 3 3 0 Type II secretion system (T2SS), protein M DivIVA PF05103.13 EHU00179.1 - 5.1 7.2 13.4 6.5 6.9 4.2 2.6 1 1 0 2 2 2 0 DivIVA protein ERM PF00769.19 EHU00179.1 - 5.2 6.8 15.6 4.7 7.0 13.9 1.7 1 1 1 2 2 2 0 Ezrin/radixin/moesin family CCDC-167 PF15188.6 EHU00179.1 - 7.6 7.0 7.7 8.8 6.8 5.7 2.2 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 LMWPc PF01451.21 EHU00180.1 - 1.8e-41 141.8 0.0 2e-41 141.7 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Poly_export PF02563.16 EHU00181.1 - 2.5e-29 101.3 0.1 2.4e-28 98.2 0.1 2.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis/export protein Wza_C PF18412.1 EHU00181.1 - 9.2e-16 57.3 2.6 1.8e-15 56.4 2.6 1.5 1 0 0 1 1 1 1 Outer-membrane lipoprotein Wza C-terminal domain SLBB PF10531.9 EHU00181.1 - 4.1e-12 45.8 1.4 1.6e-05 24.7 0.0 3.0 3 0 0 3 3 3 2 SLBB domain LysM PF01476.20 EHU00181.1 - 0.067 13.3 0.6 2.9 8.0 0.0 3.1 3 0 0 3 3 3 0 LysM domain Cupin_4 PF08007.12 EHU00181.1 - 0.1 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily protein Bac_transf PF02397.16 EHU00182.1 - 2.3e-65 219.6 0.0 6.8e-65 218.1 0.0 1.8 2 0 0 2 2 2 1 Bacterial sugar transferase CoA_binding_3 PF13727.6 EHU00182.1 - 3.5e-09 36.9 0.3 7.5e-09 35.8 0.3 1.5 1 0 0 1 1 1 1 CoA-binding domain RRM_8 PF11835.8 EHU00182.1 - 0.061 13.5 0.1 22 5.4 0.0 2.8 2 1 1 3 3 3 0 RRM-like domain TerC PF03741.16 EHU00183.1 - 8.5e-47 159.2 13.9 1.3e-46 158.5 13.9 1.3 1 0 0 1 1 1 1 Integral membrane protein TerC family CorC_HlyC PF03471.17 EHU00183.1 - 6.1e-19 67.8 0.0 3e-17 62.4 0.0 2.8 1 1 1 2 2 2 1 Transporter associated domain CBS PF00571.28 EHU00183.1 - 2.6e-14 53.4 1.2 9e-09 35.7 0.0 2.6 2 0 0 2 2 2 2 CBS domain DUF475 PF04332.15 EHU00183.1 - 0.043 13.6 6.8 0.12 12.2 6.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF475) DctQ PF04290.12 EHU00183.1 - 8.3 6.3 16.2 0.46 10.4 3.6 3.1 2 1 1 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component AsmA PF05170.14 EHU00184.1 - 7.7e-38 130.7 14.8 1.7e-19 70.1 9.1 2.1 1 1 1 2 2 2 2 AsmA family AsmA_2 PF13502.6 EHU00184.1 - 1.3e-21 77.2 18.7 3.2e-20 72.7 6.4 3.0 3 1 0 3 3 3 2 AsmA-like C-terminal region AsmA_1 PF13109.6 EHU00184.1 - 0.07 12.6 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 AsmA-like C-terminal region Big_9 PF17963.1 EHU00184.1 - 0.2 12.4 1.3 2.1 9.2 0.3 3.2 3 0 0 3 3 3 0 Bacterial Ig domain dUTPase PF00692.19 EHU00185.1 - 1.2e-10 41.2 0.0 1.5e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 dUTPase DCD PF06559.11 EHU00185.1 - 1.6e-10 40.4 0.0 1e-06 27.8 0.0 2.0 1 1 1 2 2 2 2 2'-deoxycytidine 5'-triphosphate deaminase (DCD) PRK PF00485.18 EHU00186.1 - 2.4e-43 148.2 0.1 2.9e-43 147.9 0.1 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EHU00186.1 - 1.5e-05 25.6 0.0 2.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain CoaE PF01121.20 EHU00186.1 - 0.00013 21.7 2.8 0.002 17.8 2.8 2.1 1 1 0 1 1 1 1 Dephospho-CoA kinase APS_kinase PF01583.20 EHU00186.1 - 0.0029 17.5 0.0 0.72 9.7 0.0 2.3 2 0 0 2 2 2 2 Adenylylsulphate kinase ABC_tran PF00005.27 EHU00186.1 - 0.011 16.2 0.0 0.021 15.3 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 EHU00186.1 - 0.044 14.2 0.0 0.059 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.6 EHU00186.1 - 0.055 13.9 0.2 0.47 10.9 0.1 2.2 2 1 0 2 2 2 0 AAA domain PAP2 PF01569.21 EHU00187.1 - 5.2e-08 32.7 16.6 6.1e-08 32.5 9.0 2.3 1 1 0 2 2 2 2 PAP2 superfamily GGDEF PF00990.21 EHU00188.1 - 2.5e-43 147.6 0.1 4.1e-43 146.9 0.1 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_3 PF08447.12 EHU00188.1 - 1.9e-35 121.0 0.1 2.4e-16 59.8 0.1 3.4 3 0 0 3 3 3 3 PAS fold PAS PF00989.25 EHU00188.1 - 4.2e-31 107.3 0.6 1e-10 41.6 0.0 3.8 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.7 EHU00188.1 - 5e-26 91.0 0.0 1.3e-09 38.3 0.0 3.6 3 0 0 3 3 3 3 PAS domain PAS_4 PF08448.10 EHU00188.1 - 2.3e-22 79.3 0.2 4.8e-09 36.5 0.0 4.0 4 0 0 4 4 4 3 PAS fold MASE1 PF05231.14 EHU00188.1 - 2.4e-20 72.9 45.6 3.4e-20 72.4 45.6 1.2 1 0 0 1 1 1 1 MASE1 EAL PF00563.20 EHU00188.1 - 3.9e-14 52.7 0.4 1e-13 51.4 0.4 1.7 1 0 0 1 1 1 1 EAL domain PAS_8 PF13188.7 EHU00188.1 - 2.3e-08 33.9 0.1 0.025 14.6 0.0 4.5 4 1 0 4 4 4 2 PAS domain PAS_10 PF13596.6 EHU00188.1 - 0.00044 20.8 0.0 0.023 15.3 0.0 2.8 2 0 0 2 2 2 1 PAS domain PAS_7 PF12860.7 EHU00188.1 - 0.00059 20.0 0.0 0.022 14.9 0.0 2.9 2 0 0 2 2 2 1 PAS fold GGDEF_2 PF17853.1 EHU00188.1 - 0.006 16.8 0.9 0.037 14.3 0.1 2.7 3 0 0 3 3 3 1 GGDEF-like domain Plus-3 PF03126.18 EHU00188.1 - 0.056 14.0 0.0 0.57 10.7 0.0 2.3 2 0 0 2 2 2 0 Plus-3 domain PAS_11 PF14598.6 EHU00188.1 - 0.12 12.5 0.1 17 5.5 0.0 3.2 3 0 0 3 3 3 0 PAS domain Biotin_lipoyl_2 PF13533.6 EHU00189.1 - 2.1e-15 56.3 1.6 8.6e-15 54.3 0.4 2.5 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 EHU00189.1 - 1.5e-13 51.3 1.1 1.2e-07 32.4 0.2 2.8 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 EHU00189.1 - 2.1e-13 50.0 2.2 4.5e-13 48.9 2.2 1.5 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl PF00364.22 EHU00189.1 - 0.00095 18.9 0.1 0.0044 16.8 0.0 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme ChapFlgA PF13144.6 EHU00189.1 - 0.014 15.4 7.0 5.4 7.1 0.1 3.6 2 1 1 3 3 3 0 Chaperone for flagella basal body P-ring formation PTS_EIIA_1 PF00358.20 EHU00189.1 - 0.044 13.5 0.4 0.2 11.4 0.0 2.3 3 0 0 3 3 3 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Peptidase_M23 PF01551.22 EHU00189.1 - 0.63 10.3 3.0 2.8 8.2 0.1 2.9 3 0 0 3 3 3 0 Peptidase family M23 ACR_tran PF00873.19 EHU00190.1 - 0 1159.7 29.6 0 1159.5 29.6 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family SecD_SecF PF02355.16 EHU00190.1 - 1.3e-07 31.2 32.5 1.8e-05 24.2 15.9 2.5 2 0 0 2 2 2 2 Protein export membrane protein DUF883 PF05957.13 EHU00190.1 - 0.063 13.9 1.6 3.6 8.3 0.0 4.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) ACR_tran PF00873.19 EHU00191.1 - 0 1154.7 16.2 0 1154.5 16.2 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 EHU00191.1 - 1.3e-09 37.5 27.4 2.5e-09 36.5 9.2 2.7 2 1 0 2 2 2 2 MMPL family SecD_SecF PF02355.16 EHU00191.1 - 8.2e-06 25.3 23.3 0.00032 20.1 11.6 2.6 2 0 0 2 2 2 2 Protein export membrane protein Patched PF02460.18 EHU00191.1 - 0.25 9.4 14.4 0.36 8.9 14.4 1.1 1 0 0 1 1 1 0 Patched family DUF3094 PF11293.8 EHU00191.1 - 0.48 10.2 2.0 0.93 9.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) MFS_1 PF07690.16 EHU00192.1 - 7.9e-56 189.5 62.8 1.2e-50 172.4 44.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EHU00192.1 - 1.8e-08 33.2 9.9 1.8e-08 33.2 9.9 2.5 2 1 0 2 2 2 1 Transmembrane secretion effector Sugar_tr PF00083.24 EHU00192.1 - 2.9e-06 26.4 14.1 2.9e-06 26.4 14.1 3.5 2 2 0 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.6 EHU00192.1 - 0.00039 19.1 7.2 0.00039 19.1 7.2 2.9 1 1 1 3 3 3 2 MFS/sugar transport protein TMEM192 PF14802.6 EHU00192.1 - 0.7 8.9 2.6 0.41 9.7 0.2 1.8 2 0 0 2 2 2 0 TMEM192 family HATPase_c PF02518.26 EHU00193.1 - 2.2e-22 79.7 0.0 9.6e-22 77.6 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 EHU00193.1 - 8.9e-15 54.8 1.7 4.7e-14 52.5 0.1 2.8 3 0 0 3 3 3 1 HAMP domain HisKA PF00512.25 EHU00193.1 - 4e-12 46.0 0.4 1.1e-11 44.6 0.4 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 EHU00193.1 - 0.0036 17.2 0.0 0.0088 16.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 EHU00193.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 GHKL domain SlyX PF04102.12 EHU00193.1 - 0.6 10.8 2.7 63 4.3 0.0 3.5 2 1 2 4 4 4 0 SlyX Response_reg PF00072.24 EHU00194.1 - 3e-28 98.2 0.0 4.5e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 EHU00194.1 - 1.2e-23 82.9 0.0 2.3e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Peptidase_U32 PF01136.19 EHU00195.1 - 3.6e-96 320.8 0.0 5.1e-96 320.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family U32 Peptidase_U32_C PF16325.5 EHU00195.1 - 7.3e-19 67.8 0.0 2e-18 66.4 0.0 1.8 1 0 0 1 1 1 1 Peptidase family U32 C-terminal domain Tachystatin_B PF11478.8 EHU00195.1 - 3 7.9 6.7 0.13 12.2 0.6 1.8 2 0 0 2 2 2 0 Antimicrobial chitin binding protein tachystatin B DAGK_cat PF00781.24 EHU00196.1 - 8.8e-28 96.5 0.3 1.4e-27 95.8 0.3 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 EHU00196.1 - 9.2e-05 21.8 0.1 0.00015 21.1 0.1 1.4 1 0 0 1 1 1 1 ATP-NAD kinase Peripla_BP_6 PF13458.6 EHU00196.1 - 0.012 15.3 0.0 0.018 14.7 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein Mannitol_dh_C PF08125.13 EHU00197.1 - 5.8e-88 294.5 0.0 6.9e-88 294.3 0.0 1.0 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain FCD PF07729.12 EHU00198.1 - 3.4e-20 72.7 14.3 5.3e-20 72.1 14.3 1.3 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 EHU00198.1 - 5.2e-18 64.5 1.0 1.1e-17 63.4 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 EHU00198.1 - 0.0016 18.5 0.3 0.013 15.5 0.0 2.4 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.6 EHU00198.1 - 0.095 12.3 0.0 0.29 10.7 0.0 1.9 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF3253 PF11625.8 EHU00198.1 - 0.13 12.5 0.9 2.1 8.6 0.0 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF3253) AAA_lid_6 PF17866.1 EHU00198.1 - 0.17 12.1 1.7 0.39 10.9 0.8 2.1 2 0 0 2 2 2 0 AAA lid domain Phos_pyr_kin PF08543.12 EHU00199.1 - 4.2e-91 304.7 0.0 4.8e-91 304.5 0.0 1.0 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EHU00199.1 - 0.0055 16.1 0.0 0.0082 15.5 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.15 EHU00200.1 - 1.7e-90 302.8 3.6 1.9e-90 302.6 3.6 1.0 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Carb_kinase PF01256.17 EHU00200.1 - 2.4e-05 23.9 0.8 3e-05 23.6 0.8 1.1 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 EHU00200.1 - 0.00017 21.0 0.2 0.00024 20.6 0.2 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DUF2786 PF10979.8 EHU00200.1 - 0.052 13.5 4.5 0.13 12.2 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) HTH_Tnp_1 PF01527.20 EHU00201.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU00201.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU00201.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU00201.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHU00202.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHU00203.1 - 2.2e-98 329.2 3.2 1.6e-97 326.4 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU00203.1 - 3.2e-16 59.3 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU00203.1 - 8e-15 55.0 1.3 1.9e-14 53.8 1.3 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU00203.1 - 1.7e-11 44.7 9.6 3.5e-11 43.7 9.6 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHU00203.1 - 0.017 14.9 6.4 0.027 14.3 6.4 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Phage_HK97_TLTM PF06120.11 EHU00203.1 - 0.022 14.0 1.7 0.042 13.0 1.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHU00203.1 - 0.022 15.1 4.3 0.091 13.1 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Exonuc_VII_L PF02601.15 EHU00203.1 - 0.029 14.0 1.8 0.039 13.5 0.6 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit FUSC PF04632.12 EHU00203.1 - 0.036 12.6 6.9 0.056 12.0 6.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tho2 PF11262.8 EHU00203.1 - 0.057 12.6 0.5 0.094 11.9 0.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Troponin PF00992.20 EHU00203.1 - 0.062 13.6 3.0 0.11 12.8 3.0 1.3 1 0 0 1 1 1 0 Troponin LXG PF04740.12 EHU00203.1 - 0.11 12.2 2.6 0.33 10.6 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHU00203.1 - 0.16 11.8 10.8 0.26 11.1 10.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family UME PF08064.13 EHU00203.1 - 0.16 11.9 0.5 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain HalX PF08663.10 EHU00203.1 - 0.23 11.8 3.1 0.59 10.5 3.1 1.7 1 0 0 1 1 1 0 HalX domain DHR10 PF18595.1 EHU00203.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF1192 PF06698.11 EHU00203.1 - 0.48 10.5 5.3 3.4 7.8 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHU00203.1 - 1.1 8.4 3.1 1.7 7.8 3.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHU00203.1 - 2.8 7.4 7.9 6.1 6.3 7.9 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHU00203.1 - 3.3 8.1 7.9 6.7 7.0 7.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 EHU00203.1 - 7.2 7.3 8.7 7.7 7.2 1.0 3.0 1 1 1 2 2 2 0 SlyX Resolvase PF00239.21 EHU00205.1 - 1.9e-36 125.3 0.1 2.6e-36 124.9 0.1 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_7 PF02796.15 EHU00205.1 - 8e-05 22.6 0.0 0.00023 21.2 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 EHU00205.1 - 0.0014 18.6 0.0 0.0033 17.4 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 EHU00205.1 - 0.0016 18.1 0.0 0.0041 16.9 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 EHU00205.1 - 0.0019 17.9 0.0 0.41 10.4 0.0 3.3 4 0 0 4 4 4 1 Helix-turn-helix domain DDE_Tnp_IS1 PF03400.13 EHU00206.1 - 6.1e-36 123.6 0.7 6.6e-36 123.5 0.7 1.0 1 0 0 1 1 1 1 IS1 transposase HTH_Tnp_IS1 PF12759.7 EHU00207.1 - 2.6e-18 65.3 1.0 2.8e-18 65.2 1.0 1.0 1 0 0 1 1 1 1 InsA C-terminal domain HTH_Tnp_ISL3 PF13542.6 EHU00207.1 - 0.035 13.5 0.0 0.035 13.5 0.0 1.0 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 EHU00207.1 - 0.11 12.3 0.0 0.11 12.3 0.0 1.0 1 0 0 1 1 1 0 Homeodomain-like domain Helicase_C PF00271.31 EHU00208.1 - 5.4e-08 33.2 0.0 1.6e-07 31.7 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF3258 PF11646.8 EHU00209.1 - 9.5e-05 22.5 0.1 0.00021 21.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF3258 Phage_integrase PF00589.22 EHU00209.1 - 0.013 15.3 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 Phage integrase family Mem_trans PF03547.18 EHU00211.1 - 6.2e-28 97.3 29.0 1.9e-16 59.5 12.9 2.0 1 1 1 2 2 2 2 Membrane transport protein DUF202 PF02656.15 EHU00211.1 - 0.065 13.7 0.6 0.065 13.7 0.6 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF202) DUF4133 PF13571.6 EHU00211.1 - 3.3 8.1 6.1 2 8.8 0.6 2.8 2 2 0 2 2 2 0 Domain of unknown function (DUF4133) Pyr_redox_2 PF07992.14 EHU00212.1 - 1.5e-44 152.4 4.5 2.4e-44 151.7 4.5 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EHU00212.1 - 5.2e-19 68.6 1.0 1.1e-15 57.7 0.0 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EHU00212.1 - 1.8e-15 57.3 4.4 1.3e-14 54.5 0.4 2.9 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EHU00212.1 - 1.3e-10 41.0 4.7 0.0001 21.5 0.9 3.4 2 1 1 3 3 3 3 Glucose inhibited division protein A Thioredoxin_3 PF13192.6 EHU00212.1 - 1.2e-08 34.9 0.0 3.5e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin domain FAD_binding_2 PF00890.24 EHU00212.1 - 2.2e-07 30.3 12.5 0.00056 19.1 1.4 4.7 3 2 3 6 6 6 2 FAD binding domain FAD_oxidored PF12831.7 EHU00212.1 - 1.5e-06 27.8 11.0 1.3e-05 24.8 0.6 3.1 2 1 1 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EHU00212.1 - 2.5e-05 23.2 6.5 0.062 12.0 0.6 3.3 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_3 PF01494.19 EHU00212.1 - 0.00031 20.1 3.0 0.0022 17.3 0.3 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EHU00212.1 - 0.0013 19.0 5.4 0.01 16.1 0.3 3.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EHU00212.1 - 0.0013 18.0 1.3 0.0055 16.0 0.1 2.1 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 EHU00212.1 - 0.0034 17.0 9.5 0.22 11.1 0.5 3.5 4 0 0 4 4 4 2 FAD dependent oxidoreductase Glutaredoxin PF00462.24 EHU00212.1 - 0.0066 16.6 0.5 0.067 13.4 0.0 2.6 2 0 0 2 2 2 1 Glutaredoxin AlaDh_PNT_C PF01262.21 EHU00212.1 - 0.011 15.0 1.6 1.4 8.1 0.1 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 EHU00212.1 - 0.05 12.7 0.1 0.73 8.9 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 EHU00212.1 - 0.082 11.3 0.0 0.17 10.3 0.0 1.4 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like DSBA PF01323.20 EHU00212.1 - 0.19 11.5 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 DSBA-like thioredoxin domain NAD_binding_9 PF13454.6 EHU00212.1 - 3.4 7.7 5.0 33 4.4 0.0 3.5 4 0 0 4 4 4 0 FAD-NAD(P)-binding AhpC-TSA PF00578.21 EHU00213.1 - 3.6e-33 114.1 0.0 4.5e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EHU00213.1 - 2.3e-11 43.6 0.0 3e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EHU00213.1 - 4.4e-07 29.6 0.1 7.9e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 EHU00213.1 - 8.6e-05 22.5 0.0 0.00057 19.8 0.0 2.0 2 0 0 2 2 2 1 SCO1/SenC DUF3986 PF13143.6 EHU00213.1 - 0.014 16.4 0.4 0.021 15.8 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3986) Peptidase_M28 PF04389.17 EHU00213.1 - 0.017 14.8 0.1 0.026 14.2 0.1 1.3 1 0 0 1 1 1 0 Peptidase family M28 Acetyltransf_10 PF13673.7 EHU00215.1 - 1.1e-11 44.7 0.1 1.3e-11 44.5 0.1 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EHU00215.1 - 6.1e-11 42.6 0.0 7e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EHU00215.1 - 3.9e-10 40.0 0.0 4.4e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EHU00215.1 - 0.00012 22.0 0.0 0.00017 21.5 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EHU00215.1 - 0.0011 19.0 0.0 0.024 14.8 0.0 2.0 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 EHU00215.1 - 0.019 14.9 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_9 PF13527.7 EHU00215.1 - 0.031 14.4 0.0 0.036 14.2 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3842 PF12953.7 EHU00215.1 - 0.078 13.4 0.0 0.097 13.1 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3842) Acetyltransf_15 PF17013.5 EHU00215.1 - 0.15 11.5 0.0 0.32 10.4 0.0 1.7 1 1 0 1 1 1 0 Putative acetyl-transferase ParA PF10609.9 EHU00216.1 - 1.1e-97 326.3 0.0 1.4e-97 326.0 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EHU00216.1 - 8e-10 38.9 0.0 1.8e-09 37.8 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EHU00216.1 - 1e-08 35.3 0.1 2.3e-07 30.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 EHU00216.1 - 2e-08 33.9 0.0 3.3e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 EHU00216.1 - 1.7e-05 24.4 0.0 0.0035 16.8 0.0 2.3 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family FeS_assembly_P PF01883.19 EHU00216.1 - 0.00071 19.7 0.0 0.0018 18.4 0.0 1.7 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein ArsA_ATPase PF02374.15 EHU00216.1 - 0.012 14.9 2.5 0.031 13.5 0.3 2.3 2 1 0 2 2 2 0 Anion-transporting ATPase VirC1 PF07015.11 EHU00216.1 - 0.018 14.3 0.1 0.034 13.4 0.1 1.4 1 0 0 1 1 1 0 VirC1 protein tRNA-synt_1g PF09334.11 EHU00217.1 - 2.5e-162 540.1 0.0 3.1e-162 539.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA_bind PF01588.20 EHU00217.1 - 9.6e-22 76.9 0.0 2e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1 PF00133.22 EHU00217.1 - 8.7e-16 57.3 1.6 2.4e-10 39.3 0.1 2.5 3 0 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 EHU00217.1 - 6.6e-11 42.1 0.3 0.00016 21.1 0.0 2.4 2 1 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 EHU00217.1 - 3e-06 26.4 0.0 0.00047 19.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (K) Anticodon_1 PF08264.13 EHU00217.1 - 0.00084 19.3 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA DDE_3 PF13358.6 EHU00218.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHU00218.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHU00218.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHU00218.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHU00218.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHU00218.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHU00218.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHU00218.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 LrgA PF03788.14 EHU00219.1 - 4.6e-26 90.6 9.8 5.2e-26 90.4 9.8 1.0 1 0 0 1 1 1 1 LrgA family LrgB PF04172.16 EHU00220.1 - 1.4e-74 250.3 20.9 1.6e-74 250.1 20.9 1.0 1 0 0 1 1 1 1 LrgB-like family Transgly_assoc PF04226.13 EHU00220.1 - 0.85 9.9 11.9 0.22 11.8 1.7 3.5 3 0 0 3 3 3 0 Transglycosylase associated protein dCMP_cyt_deam_2 PF08211.12 EHU00221.1 - 4.5e-41 140.2 0.6 4.5e-41 140.2 0.6 2.2 2 1 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_1 PF00383.23 EHU00221.1 - 8.8e-13 48.0 0.5 1.3e-11 44.3 0.1 2.1 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EHU00221.1 - 0.1 12.3 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 MafB19-like deaminase Pput2613-deam PF14427.6 EHU00221.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Pput_2613-like deaminase SLATT_3 PF18184.1 EHU00221.1 - 0.26 11.4 2.3 0.57 10.3 2.3 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 3 Malic_M PF03949.15 EHU00222.1 - 5.8e-105 350.2 0.3 9.5e-105 349.5 0.0 1.4 2 0 0 2 2 2 1 Malic enzyme, NAD binding domain malic PF00390.19 EHU00222.1 - 6.9e-82 273.7 0.0 4.2e-81 271.1 0.0 2.0 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain HAD PF12710.7 EHU00222.1 - 0.08 13.3 0.0 0.24 11.8 0.0 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF218 PF02698.17 EHU00223.1 - 3.4e-17 62.7 0.0 4.4e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 DUF218 domain BPD_transp_2 PF02653.16 EHU00224.1 - 6.3e-50 169.8 36.8 6.3e-50 169.8 36.8 1.3 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component DUF543 PF04418.12 EHU00224.1 - 5.8 7.0 6.9 5.1 7.2 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF543) ABC_tran PF00005.27 EHU00225.1 - 2.9e-48 163.9 0.3 8.2e-29 100.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EHU00225.1 - 1.9e-09 37.7 0.1 0.0032 17.3 0.0 3.3 2 1 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EHU00225.1 - 0.001 18.7 0.0 0.0027 17.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EHU00225.1 - 0.0011 18.4 0.9 0.012 15.0 0.6 2.6 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EHU00225.1 - 0.0013 19.2 0.5 0.0051 17.3 0.1 2.2 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EHU00225.1 - 0.0016 18.3 0.0 0.0059 16.5 0.0 2.0 1 0 0 1 1 1 1 RsgA GTPase AAA_27 PF13514.6 EHU00225.1 - 0.0038 16.8 0.0 0.0071 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF2813 PF11398.8 EHU00225.1 - 0.0067 15.7 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2813) AAA_16 PF13191.6 EHU00225.1 - 0.0085 16.5 0.0 0.015 15.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_13 PF13166.6 EHU00225.1 - 0.017 13.8 0.0 1.8 7.1 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 EHU00225.1 - 0.048 13.4 0.2 0.048 13.4 0.2 1.9 3 0 0 3 3 3 0 AAA ATPase domain AAA_30 PF13604.6 EHU00225.1 - 0.081 12.6 0.0 0.44 10.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EHU00225.1 - 0.092 12.8 0.0 0.31 11.1 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 EHU00225.1 - 0.16 12.3 0.2 0.47 10.7 0.2 1.9 1 1 0 1 1 1 0 AAA domain Peripla_BP_4 PF13407.6 EHU00226.1 - 2.7e-65 220.5 15.7 3.1e-65 220.3 15.7 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 EHU00226.1 - 5.5e-11 42.4 3.3 2e-10 40.6 3.3 1.7 1 1 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 EHU00226.1 - 3.9e-08 33.8 0.3 9.4e-08 32.6 0.1 1.6 2 0 0 2 2 2 1 Periplasmic binding protein-like domain PucR PF07905.11 EHU00226.1 - 0.0021 18.3 0.2 0.0067 16.7 0.1 1.9 2 0 0 2 2 2 1 Purine catabolism regulatory protein-like family TPP_enzyme_C PF02775.21 EHU00226.1 - 0.12 12.2 3.8 0.14 11.9 0.7 2.0 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Peripla_BP_3 PF13377.6 EHU00227.1 - 1.5e-34 119.7 0.1 3.4e-34 118.6 0.1 1.6 1 0 0 1 1 1 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 EHU00227.1 - 3.2e-23 82.6 0.1 4.3e-23 82.1 0.1 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 EHU00227.1 - 5.3e-20 71.0 2.1 1.8e-19 69.2 2.0 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 EHU00227.1 - 2.6e-15 56.7 0.0 4.9e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Periplasmic binding protein domain HTH_31 PF13560.6 EHU00227.1 - 0.0006 20.1 3.1 0.00063 20.0 0.5 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 EHU00227.1 - 0.00079 19.4 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_Tnp_ISL3 PF13542.6 EHU00227.1 - 0.0019 17.6 0.5 0.0061 16.0 0.5 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_7 PF02796.15 EHU00227.1 - 0.01 15.9 0.1 0.029 14.5 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_38 PF13936.6 EHU00227.1 - 0.013 15.2 1.8 0.088 12.6 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma54_DBD PF04552.13 EHU00227.1 - 0.019 14.7 1.0 0.58 9.9 0.2 2.4 1 1 1 2 2 2 0 Sigma-54, DNA binding domain HTH_23 PF13384.6 EHU00227.1 - 0.019 14.7 0.1 0.067 13.0 0.1 2.0 1 1 0 1 1 1 0 Homeodomain-like domain HTH_26 PF13443.6 EHU00227.1 - 0.027 14.9 0.0 0.066 13.7 0.0 1.7 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 EHU00227.1 - 0.049 13.2 0.1 0.14 11.7 0.1 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Trp_repressor PF01371.19 EHU00227.1 - 0.066 13.3 0.2 0.14 12.3 0.2 1.6 1 0 0 1 1 1 0 Trp repressor protein TetR_N PF00440.23 EHU00227.1 - 0.089 12.6 0.2 0.27 11.0 0.2 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family HTH_IclR PF09339.10 EHU00227.1 - 0.1 12.4 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain DUF418 PF04235.12 EHU00228.1 - 5e-41 140.4 14.4 5e-41 140.4 14.4 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF418) Clc-like PF07062.12 EHU00228.1 - 1.2 8.6 5.1 0.21 11.1 0.4 2.1 3 0 0 3 3 3 0 Clc-like GTP_cyclohydroI PF01227.22 EHU00229.1 - 2.5e-63 212.8 0.4 2.9e-63 212.5 0.4 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 EHU00229.1 - 0.07 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 QueF-like protein MFS_4 PF06779.14 EHU00230.1 - 4.1e-86 289.5 44.9 4.7e-86 289.3 44.9 1.0 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1 PF07690.16 EHU00230.1 - 7.5e-13 48.1 72.8 6e-12 45.2 47.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily stn_TNFRSF12A PF12191.8 EHU00230.1 - 0.34 11.1 6.6 0.2 11.9 0.8 3.0 2 1 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain LysR_substrate PF03466.20 EHU00231.1 - 1.3e-36 126.0 0.2 1.7e-36 125.6 0.2 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EHU00231.1 - 1.4e-16 60.2 0.4 2.7e-16 59.2 0.4 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 EHU00231.1 - 0.00021 21.0 0.1 0.00066 19.4 0.1 1.8 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain DUF2157 PF09925.9 EHU00231.1 - 0.089 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) ADH_N PF08240.12 EHU00232.1 - 7.4e-26 90.2 0.5 7.4e-26 90.2 0.5 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EHU00232.1 - 6.9e-24 84.3 0.1 1.2e-23 83.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EHU00232.1 - 0.00016 22.7 0.0 0.00033 21.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EHU00232.1 - 0.0002 20.9 0.2 0.00096 18.7 0.0 2.1 2 1 0 2 2 2 1 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 EHU00232.1 - 0.042 13.4 0.1 0.066 12.8 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Met_10 PF02475.16 EHU00232.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Esterase PF00756.20 EHU00233.1 - 8.1e-64 215.7 0.0 9.3e-64 215.5 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 EHU00233.1 - 1.5e-05 24.5 0.0 2.2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EHU00233.1 - 3.4e-05 23.2 0.4 0.0012 18.1 0.2 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Esterase_phd PF10503.9 EHU00233.1 - 0.00015 21.4 0.0 0.022 14.2 0.0 2.1 2 0 0 2 2 2 2 Esterase PHB depolymerase Chlorophyllase2 PF12740.7 EHU00233.1 - 0.00024 20.1 0.0 0.00036 19.5 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 EHU00233.1 - 0.00089 19.9 0.9 0.00089 19.9 0.9 2.0 1 1 0 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 EHU00233.1 - 0.011 14.8 0.0 0.021 13.8 0.0 1.4 2 0 0 2 2 2 0 Chlorophyllase NHR2 PF08788.11 EHU00233.1 - 0.026 14.3 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 NHR2 domain like Lipase_3 PF01764.25 EHU00233.1 - 0.046 13.6 0.0 0.063 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) DUF1057 PF06342.12 EHU00233.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Thioesterase PF00975.20 EHU00233.1 - 0.34 11.0 2.2 4.1 7.5 0.8 2.3 1 1 0 2 2 2 0 Thioesterase domain ABC_tran PF00005.27 EHU00234.1 - 3.8e-28 98.7 0.0 4.9e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EHU00234.1 - 8.7e-15 55.3 0.6 1.6e-06 28.2 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EHU00234.1 - 2.2e-09 37.1 0.1 3e-07 30.1 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 EHU00234.1 - 3.3e-05 23.6 0.0 5.8e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EHU00234.1 - 3.3e-05 24.5 0.0 4.6e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EHU00234.1 - 7.3e-05 22.4 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Rad17 PF03215.15 EHU00234.1 - 0.00025 21.0 0.0 0.00042 20.3 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_13 PF13166.6 EHU00234.1 - 0.00028 19.7 0.0 0.47 9.0 0.0 2.0 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EHU00234.1 - 0.00033 21.1 0.1 0.00056 20.3 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 EHU00234.1 - 0.00093 19.0 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EHU00234.1 - 0.00095 19.1 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase ABC_ATPase PF09818.9 EHU00234.1 - 0.0032 16.3 0.0 0.058 12.2 0.0 2.0 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_22 PF13401.6 EHU00234.1 - 0.0034 17.6 0.0 0.0066 16.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EHU00234.1 - 0.0069 16.6 0.0 0.0097 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EHU00234.1 - 0.012 16.0 0.0 0.025 15.0 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EHU00234.1 - 0.016 14.9 0.1 0.054 13.2 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.6 EHU00234.1 - 0.017 15.3 0.0 0.039 14.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EHU00234.1 - 0.02 14.8 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 EHU00234.1 - 0.029 14.4 0.1 0.07 13.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Adeno_IVa2 PF02456.15 EHU00234.1 - 0.032 13.0 0.0 0.052 12.3 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_30 PF13604.6 EHU00234.1 - 0.032 13.9 0.0 0.052 13.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain HSM3_N PF18795.1 EHU00234.1 - 0.033 13.6 0.0 0.043 13.2 0.0 1.1 1 0 0 1 1 1 0 DNA mismatch repair protein HSM3, N terminal domain ATPase_2 PF01637.18 EHU00234.1 - 0.035 14.0 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_27 PF13514.6 EHU00234.1 - 0.04 13.5 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EHU00234.1 - 0.058 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EHU00234.1 - 0.11 13.0 0.0 0.22 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EHU00234.1 - 0.2 11.7 0.2 0.33 11.1 0.2 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase FecCD PF01032.18 EHU00235.1 - 1e-85 287.5 38.6 1.2e-85 287.3 38.6 1.0 1 0 0 1 1 1 1 FecCD transport family ABC-3 PF00950.17 EHU00235.1 - 0.0004 20.0 23.1 0.00061 19.4 23.1 1.3 1 0 0 1 1 1 1 ABC 3 transport family DUF1430 PF07242.11 EHU00235.1 - 4.4 7.6 5.8 45 4.4 1.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1430) RVT_1 PF00078.27 EHU00236.1 - 8.7e-43 146.4 0.0 1.7e-42 145.4 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) GIIM PF08388.11 EHU00236.1 - 1.2e-17 63.7 4.0 3e-17 62.4 4.0 1.7 1 0 0 1 1 1 1 Group II intron, maturase-specific domain AA_permease PF00324.21 EHU00237.1 - 6.6e-142 473.5 36.9 7.9e-142 473.2 36.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EHU00237.1 - 1.9e-41 142.3 40.7 2.7e-41 141.8 40.7 1.3 1 1 0 1 1 1 1 Amino acid permease LysR_substrate PF03466.20 EHU00238.1 - 1.1e-46 158.8 0.1 1.7e-46 158.2 0.1 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EHU00238.1 - 5.8e-18 64.6 2.7 1.1e-17 63.8 1.2 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family PBP_like PF12727.7 EHU00238.1 - 2.8e-05 23.3 0.0 8.8e-05 21.7 0.0 1.6 1 1 0 2 2 2 1 PBP superfamily domain DUF1232 PF06803.12 EHU00239.1 - 1.6e-13 50.2 8.1 1.6e-13 50.2 8.1 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1232) Sigma_M_inh PF17453.2 EHU00239.1 - 0.041 14.3 0.4 0.056 13.9 0.4 1.2 1 0 0 1 1 1 0 Sigma-M inhibitor Cons_hypoth698 PF03601.14 EHU00240.1 - 2.3e-102 342.0 20.8 2.6e-102 341.8 20.8 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein 698 Transposase_31 PF04754.12 EHU00241.1 - 4.6e-83 277.8 0.1 6.2e-83 277.4 0.1 1.2 1 0 0 1 1 1 1 Putative transposase, YhgA-like AP_endonuc_2 PF01261.24 EHU00242.1 - 1.7e-39 135.5 0.3 2.5e-39 134.9 0.3 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel PTS_IIB PF02302.17 EHU00243.1 - 8.4e-22 77.7 1.3 6.4e-18 65.2 0.3 2.6 2 0 0 2 2 2 2 PTS system, Lactose/Cellobiose specific IIB subunit PTS_EIIC PF02378.18 EHU00243.1 - 4.3e-14 52.3 35.8 4.3e-14 52.3 35.8 3.0 2 1 0 2 2 2 1 Phosphotransferase system, EIIC DUF745 PF05335.13 EHU00243.1 - 0.016 15.0 4.1 0.1 12.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) PfkB PF00294.24 EHU00244.1 - 4.8e-66 223.1 0.0 6.3e-66 222.7 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EHU00244.1 - 0.0012 18.3 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PcrB PF01884.17 EHU00244.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 PcrB family PTS_EIIA_2 PF00359.22 EHU00245.1 - 4.1e-32 111.1 0.0 7.4e-28 97.3 0.0 2.6 2 1 0 2 2 2 2 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 PTS-HPr PF00381.19 EHU00245.1 - 1.5e-26 92.4 0.1 3.2e-25 88.2 0.0 2.6 2 0 0 2 2 2 1 PTS HPr component phosphorylation site CxxCxxCC PF03692.15 EHU00246.1 - 2.1e-06 28.3 3.6 5.2e-06 27.1 3.6 1.7 1 1 0 1 1 1 1 Putative zinc- or iron-chelating domain Elong-fact-P_C PF09285.11 EHU00247.1 - 2.7e-17 62.2 0.0 7.6e-17 60.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP_N PF08207.12 EHU00247.1 - 6.5e-17 61.3 0.8 1.4e-16 60.2 0.3 1.8 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain EFP PF01132.20 EHU00247.1 - 7.5e-15 54.7 0.3 1.4e-14 53.8 0.3 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain DUF4357 PF14267.6 EHU00247.1 - 0.0096 15.8 0.1 0.031 14.2 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4357) cobW PF02492.19 EHU00248.1 - 3.5e-40 137.4 0.0 4.4e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EHU00248.1 - 0.00025 20.9 0.0 0.00058 19.7 0.0 1.7 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain PAP2 PF01569.21 EHU00249.1 - 5.8e-10 39.1 5.5 5.8e-10 39.1 5.5 2.5 2 1 0 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.6 EHU00249.1 - 5.8e-06 26.1 13.0 5.8e-06 26.1 13.0 1.9 2 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 EHU00249.1 - 0.37 11.3 5.1 0.24 11.9 1.9 2.3 2 0 0 2 2 2 0 PAP2 superfamily C-terminal SpoIIIAC PF06686.11 EHU00249.1 - 0.53 10.5 3.1 16 5.8 0.0 2.8 2 0 0 2 2 2 0 Stage III sporulation protein AC/AD protein family YibE_F PF07907.11 EHU00249.1 - 5.7 6.4 10.9 4.4 6.7 0.8 2.2 2 0 0 2 2 2 0 YibE/F-like protein NLPC_P60 PF00877.19 EHU00250.1 - 2.7e-32 110.9 0.0 4.5e-32 110.2 0.0 1.3 1 0 0 1 1 1 1 NlpC/P60 family Peptidase_C92 PF05708.12 EHU00250.1 - 0.0026 17.9 0.0 1.8 8.6 0.0 2.2 1 1 1 2 2 2 2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family Amidase_5 PF05382.13 EHU00250.1 - 0.025 14.5 0.0 0.052 13.4 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage peptidoglycan hydrolase CHAP PF05257.16 EHU00250.1 - 0.025 15.1 0.0 0.049 14.2 0.0 1.6 1 0 0 1 1 1 0 CHAP domain LRAT PF04970.13 EHU00250.1 - 0.047 14.0 0.0 0.12 12.7 0.0 1.6 2 0 0 2 2 2 0 Lecithin retinol acyltransferase DUF1287 PF06940.11 EHU00250.1 - 0.062 13.0 0.0 0.54 9.9 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1287) DHQS PF01959.16 EHU00250.1 - 0.15 11.0 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 3-dehydroquinate synthase II E1-E2_ATPase PF00122.20 EHU00250.1 - 0.21 11.1 0.0 0.59 9.6 0.0 1.6 2 0 0 2 2 2 0 E1-E2 ATPase CSS-motif PF12792.7 EHU00251.1 - 5.7e-25 88.0 0.4 7e-25 87.7 0.4 1.2 1 0 0 1 1 1 1 CSS motif domain associated with EAL EAL PF00563.20 EHU00252.1 - 1e-56 192.1 0.0 1.2e-56 192.0 0.0 1.0 1 0 0 1 1 1 1 EAL domain SBP_bac_5 PF00496.22 EHU00253.1 - 5.9e-72 242.7 3.8 8e-72 242.3 3.8 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle BPD_transp_1 PF00528.22 EHU00254.1 - 1.8e-36 125.6 13.6 1.8e-36 125.6 13.6 1.8 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 EHU00255.1 - 1.8e-27 96.3 12.4 1.8e-27 96.3 12.4 1.7 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 EHU00255.1 - 3.4e-07 30.1 0.9 3.4e-07 30.1 0.9 4.2 4 2 0 4 4 4 1 N-terminal TM domain of oligopeptide transport permease C ABC_tran PF00005.27 EHU00256.1 - 7.4e-60 201.4 0.0 3.1e-30 105.5 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EHU00256.1 - 5.3e-12 46.2 3.2 9.6e-05 22.3 0.1 4.0 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EHU00256.1 - 1.8e-11 43.9 0.6 0.00017 21.1 0.5 3.0 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain oligo_HPY PF08352.12 EHU00256.1 - 3.1e-08 34.0 0.0 0.013 16.0 0.0 2.5 2 0 0 2 2 2 2 Oligopeptide/dipeptide transporter, C-terminal region AAA_16 PF13191.6 EHU00256.1 - 5.4e-07 30.2 7.4 0.0037 17.7 0.7 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EHU00256.1 - 7.1e-07 29.6 6.1 0.028 14.7 0.2 3.7 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EHU00256.1 - 1.5e-06 28.0 0.3 0.016 14.8 0.1 2.6 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EHU00256.1 - 4.3e-06 26.4 0.2 0.072 12.8 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_7 PF12775.7 EHU00256.1 - 0.00032 20.3 0.1 0.081 12.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region TniB PF05621.11 EHU00256.1 - 0.00088 18.7 3.8 1.3 8.3 0.2 4.1 4 1 0 4 4 4 1 Bacterial TniB protein AAA_13 PF13166.6 EHU00256.1 - 0.00088 18.0 0.0 0.4 9.3 0.0 2.1 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 EHU00256.1 - 0.0015 18.7 0.3 1.1 9.6 0.0 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit IstB_IS21 PF01695.17 EHU00256.1 - 0.0019 17.9 2.6 1.4 8.6 0.0 3.8 4 0 0 4 4 4 1 IstB-like ATP binding protein DUF87 PF01935.17 EHU00256.1 - 0.0025 18.0 0.5 1.9 8.5 0.1 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_5 PF07728.14 EHU00256.1 - 0.0025 17.8 1.7 1.9 8.5 0.0 2.9 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) CbiA PF01656.23 EHU00256.1 - 0.0044 17.1 2.5 2.3 8.3 0.5 2.7 2 1 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain AIG1 PF04548.16 EHU00256.1 - 0.0045 16.4 0.2 2.9 7.2 0.0 2.5 2 0 0 2 2 2 2 AIG1 family G-alpha PF00503.20 EHU00256.1 - 0.0045 16.2 0.0 1.8 7.7 0.0 2.1 2 0 0 2 2 2 2 G-protein alpha subunit ResIII PF04851.15 EHU00256.1 - 0.0083 16.1 0.3 5.9 6.9 0.0 3.3 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit RsgA_GTPase PF03193.16 EHU00256.1 - 0.0093 15.9 1.4 2.7 7.9 0.2 2.4 2 0 0 2 2 2 1 RsgA GTPase Pox_A32 PF04665.12 EHU00256.1 - 0.0096 15.4 1.0 2.2 7.7 0.0 2.6 3 0 0 3 3 3 1 Poxvirus A32 protein AAA PF00004.29 EHU00256.1 - 0.0097 16.3 0.6 7.4 7.0 0.0 3.5 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EHU00256.1 - 0.036 13.8 3.1 8.7 6.0 0.2 3.6 2 2 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 EHU00256.1 - 0.042 12.8 0.2 2.9 6.7 0.0 2.8 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.6 EHU00256.1 - 0.045 13.5 0.2 9.4 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EHU00256.1 - 0.058 13.6 3.1 6.9 6.8 0.0 3.6 2 1 1 3 3 3 0 AAA domain APS_kinase PF01583.20 EHU00256.1 - 0.065 13.1 0.5 5.6 6.8 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase Mg_chelatase PF01078.21 EHU00256.1 - 0.07 12.5 0.1 2.7 7.3 0.0 2.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EHU00256.1 - 0.13 12.8 0.0 15 6.1 0.0 3.4 4 0 0 4 4 4 0 AAA domain RNA_helicase PF00910.22 EHU00256.1 - 0.14 12.5 0.0 20 5.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Sigma54_activat PF00158.26 EHU00256.1 - 0.15 11.7 0.0 0.15 11.7 0.0 3.1 4 0 0 4 4 4 0 Sigma-54 interaction domain NACHT PF05729.12 EHU00256.1 - 0.29 11.0 8.5 1.7 8.6 0.0 3.8 3 1 0 3 3 3 0 NACHT domain Hpr_kinase_C PF07475.12 EHU00256.1 - 1.9 8.0 4.8 8.7 5.8 0.1 2.7 3 0 0 3 3 2 0 HPr Serine kinase C-terminal domain YejG PF13989.6 EHU00257.1 - 1.3e-43 147.8 0.1 1.4e-43 147.6 0.1 1.0 1 0 0 1 1 1 1 YejG-like protein DUF503 PF04456.12 EHU00257.1 - 0.034 14.0 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF503) MFS_1 PF07690.16 EHU00258.1 - 3.5e-45 154.5 46.3 3.5e-45 154.5 46.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EHU00258.1 - 4.2e-11 42.4 36.5 1.5e-10 40.5 11.4 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 EHU00258.1 - 3.7e-06 25.6 4.6 6.3e-06 24.9 4.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 EHU00258.1 - 8.8e-05 22.0 32.9 0.00029 20.3 32.9 1.8 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 EHU00258.1 - 0.00063 18.4 31.4 0.00096 17.8 19.3 2.4 1 1 1 2 2 2 2 MFS/sugar transport protein PseudoU_synth_2 PF00849.22 EHU00259.1 - 1.1e-18 67.9 0.0 2.2e-18 66.8 0.0 1.5 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 EHU00259.1 - 1.8e-10 40.4 0.1 3e-10 39.6 0.1 1.4 1 0 0 1 1 1 1 S4 domain ResIII PF04851.15 EHU00260.1 - 6.6e-26 91.3 0.0 1.1e-25 90.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EHU00260.1 - 1.3e-12 48.1 0.0 3.5e-12 46.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SWI2_SNF2 PF18766.1 EHU00260.1 - 5.6e-10 39.3 0.1 1.3e-09 38.1 0.0 1.6 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DEAD PF00270.29 EHU00260.1 - 2.8e-09 37.0 0.0 1.1e-08 35.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 EHU00260.1 - 5.2e-05 23.1 0.1 0.00013 21.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain SNF2_N PF00176.23 EHU00260.1 - 0.0044 15.8 0.0 0.0066 15.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain UPF0547 PF10571.9 EHU00260.1 - 0.0053 16.8 10.9 0.0077 16.3 3.9 2.4 2 0 0 2 2 2 1 Uncharacterised protein family UPF0547 AAA_22 PF13401.6 EHU00260.1 - 0.0073 16.6 0.0 0.02 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain zf-tcix PF14952.6 EHU00260.1 - 0.013 15.1 3.2 0.048 13.3 0.3 2.4 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding DUF2075 PF09848.9 EHU00260.1 - 0.037 13.3 0.0 0.061 12.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) zinc_ribbon_2 PF13240.6 EHU00260.1 - 0.047 13.4 10.6 0.35 10.6 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain MciZ PF13072.6 EHU00260.1 - 0.12 12.2 0.3 0.3 11.0 0.3 1.6 1 0 0 1 1 1 0 Mother cell inhibitor of FtsZ zf-ribbon_3 PF13248.6 EHU00260.1 - 0.14 11.6 8.7 8 6.0 0.1 3.1 2 1 1 3 3 3 0 zinc-ribbon domain DZR PF12773.7 EHU00260.1 - 0.46 10.6 10.6 0.61 10.1 3.2 2.3 1 1 1 2 2 2 0 Double zinc ribbon Ribosomal_L25p PF01386.19 EHU00261.1 - 8.9e-24 83.8 0.1 9.9e-24 83.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal L25p family KapB PF08810.10 EHU00261.1 - 0.048 13.8 0.1 0.065 13.4 0.1 1.2 1 0 0 1 1 1 0 Kinase associated protein B NA37 PF04245.13 EHU00262.1 - 4.7e-95 318.6 0.0 5.3e-95 318.5 0.0 1.0 1 0 0 1 1 1 1 37-kD nucleoid-associated bacterial protein DUF1414 PF07208.11 EHU00263.1 - 8.2e-24 83.3 0.6 1.4e-23 82.6 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1414) DUF3413 PF11893.8 EHU00264.1 - 2.4e-105 351.2 12.3 3.5e-105 350.6 12.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3413) Sulfatase PF00884.23 EHU00264.1 - 6.1e-20 71.8 0.9 1.3e-19 70.8 0.9 1.5 1 1 0 1 1 1 1 Sulfatase DUF4968 PF16338.5 EHU00264.1 - 0.0021 18.3 0.0 0.0038 17.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) CBP_BcsG PF11658.8 EHU00264.1 - 0.0026 16.2 1.9 0.017 13.6 0.0 2.2 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsG DUF229 PF02995.17 EHU00264.1 - 0.05 12.2 0.0 0.071 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Phage_integrase PF00589.22 EHU00265.1 - 4.3e-25 88.5 0.3 1.4e-24 86.8 0.0 1.9 2 1 1 3 3 3 1 Phage integrase family Arm-DNA-bind_3 PF13356.6 EHU00265.1 - 1.7e-18 66.7 0.2 3.4e-18 65.8 0.2 1.5 1 0 0 1 1 1 1 Arm DNA-binding domain Phage_int_SAM_3 PF14659.6 EHU00265.1 - 1.8e-05 24.9 0.1 5.3e-05 23.4 0.1 1.8 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Ribosomal_S20p PF01649.18 EHU00265.1 - 0.095 13.3 1.2 1.1 9.9 0.1 2.6 2 1 0 2 2 2 0 Ribosomal protein S20 DDE_3 PF13358.6 EHU00267.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHU00267.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHU00267.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHU00267.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHU00267.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHU00267.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHU00267.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHU00267.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 DDE_Tnp_IS66 PF03050.14 EHU00268.1 - 1.3e-97 326.7 3.8 3.8e-97 325.1 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU00268.1 - 3e-16 59.3 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU00268.1 - 1.4e-14 54.2 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU00268.1 - 8.8e-11 42.4 8.7 1.9e-10 41.4 8.7 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHU00268.1 - 0.023 14.5 5.9 0.036 13.8 5.9 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Phage_HK97_TLTM PF06120.11 EHU00268.1 - 0.028 13.6 1.5 0.054 12.7 1.5 1.4 1 0 0 1 1 1 0 Tail length tape measure protein FUSC PF04632.12 EHU00268.1 - 0.03 12.9 6.3 0.048 12.2 6.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Csm1_N PF18504.1 EHU00268.1 - 0.032 14.6 4.4 0.12 12.8 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Tho2 PF11262.8 EHU00268.1 - 0.044 13.0 0.5 0.074 12.2 0.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Exonuc_VII_L PF02601.15 EHU00268.1 - 0.096 12.2 2.0 0.12 11.9 0.7 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit ERM PF00769.19 EHU00268.1 - 0.14 11.9 9.9 0.23 11.2 9.9 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family UME PF08064.13 EHU00268.1 - 0.17 11.8 0.5 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain HalX PF08663.10 EHU00268.1 - 0.19 12.1 3.0 0.49 10.7 3.0 1.7 1 0 0 1 1 1 0 HalX domain LXG PF04740.12 EHU00268.1 - 0.29 10.8 2.3 1.1 9.0 0.3 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily Zn-ribbon_8 PF09723.10 EHU00268.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DHR10 PF18595.1 EHU00268.1 - 0.52 10.4 10.4 0.91 9.6 10.4 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF1192 PF06698.11 EHU00268.1 - 1 9.4 6.1 4 7.6 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) HAUS-augmin3 PF14932.6 EHU00268.1 - 4.2 6.9 7.3 9.3 5.7 7.3 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 SlyX PF04102.12 EHU00268.1 - 6.1 7.5 8.3 8.1 7.1 1.0 3.0 1 1 0 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHU00269.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHU00270.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU00270.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU00270.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU00270.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix Porin_1 PF00267.21 EHU00271.1 - 2.5e-131 438.2 30.6 2.8e-131 438.0 30.6 1.0 1 0 0 1 1 1 1 Gram-negative porin Porin_4 PF13609.6 EHU00271.1 - 3.3e-16 59.9 49.8 3.3e-16 59.9 49.8 1.3 1 1 0 1 1 1 1 Gram-negative porin MFS_Mycoplasma PF07672.13 EHU00273.1 - 0.054 12.8 0.1 0.055 12.7 0.1 1.0 1 0 0 1 1 1 0 Mycoplasma MFS transporter DUF2681 PF10883.8 EHU00273.1 - 0.1 13.0 0.2 0.11 12.9 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) ApbE PF02424.15 EHU00274.1 - 9.2e-80 267.9 0.3 1.1e-79 267.6 0.3 1.0 1 0 0 1 1 1 1 ApbE family 2OG-FeII_Oxy_2 PF13532.6 EHU00275.1 - 4.4e-53 180.4 0.0 5.3e-53 180.1 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 EHU00275.1 - 0.0082 17.0 0.0 0.025 15.5 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily ABC_tran PF00005.27 EHU00276.1 - 5.2e-28 98.3 0.0 8.7e-28 97.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EHU00276.1 - 1.1e-07 32.0 0.6 0.0076 16.1 0.1 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EHU00276.1 - 2e-05 25.1 0.1 4.6e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain ABC_membrane PF00664.23 EHU00276.1 - 0.00015 21.6 5.5 0.00015 21.6 5.5 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 EHU00276.1 - 0.0028 17.1 0.1 2.5 7.5 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EHU00276.1 - 0.0035 17.1 0.1 0.0098 15.6 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EHU00276.1 - 0.0037 17.0 0.0 0.022 14.5 0.0 1.7 1 1 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 EHU00276.1 - 0.038 13.3 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.14 EHU00276.1 - 0.07 13.1 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 EHU00276.1 - 0.087 12.4 0.2 0.42 10.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 EHU00276.1 - 0.093 12.6 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_33 PF13671.6 EHU00276.1 - 0.1 12.8 0.0 0.35 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 EHU00276.1 - 0.12 12.2 0.1 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_23 PF13476.6 EHU00276.1 - 0.16 12.5 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Bromo_TP PF07524.13 EHU00277.1 - 0.17 11.9 0.0 0.26 11.3 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated MS_channel PF00924.18 EHU00278.1 - 9.3e-39 133.1 1.8 2.7e-38 131.6 1.8 1.7 1 1 0 1 1 1 1 Mechanosensitive ion channel MFS_1 PF07690.16 EHU00278.1 - 0.14 11.1 5.0 0.21 10.5 5.0 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily Atg14 PF10186.9 EHU00278.1 - 0.3 10.1 3.3 0.56 9.2 2.9 1.5 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Alpha-L-AF_C PF06964.12 EHU00279.1 - 5.9e-39 133.9 0.0 9.1e-39 133.3 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain HTH_17 PF12728.7 EHU00280.1 - 0.02 15.0 0.0 0.046 13.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_28 PF13518.6 EHU00280.1 - 0.024 14.8 0.2 0.072 13.2 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain YdaS_antitoxin PF15943.5 EHU00280.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DUF2213 PF09979.9 EHU00281.1 - 0.00072 19.6 0.0 0.0016 18.4 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2213) His_Phos_1 PF00300.22 EHU00282.1 - 0.038 13.7 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Ferrochelatase PF00762.19 EHU00285.1 - 1.7e-101 339.5 0.0 1.9e-101 339.3 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 EHU00285.1 - 3.5e-05 24.1 0.0 0.0021 18.3 0.0 2.3 2 0 0 2 2 2 1 CbiX Glyco_hydro_70 PF02324.16 EHU00285.1 - 0.065 11.4 0.0 0.089 11.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 MFS_3 PF05977.13 EHU00287.1 - 1.6e-25 89.5 11.4 1.9e-25 89.2 11.4 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.16 EHU00287.1 - 7.6e-18 64.6 18.2 8.4e-18 64.4 18.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.13 EHU00288.1 - 6.9e-13 47.8 11.6 7.9e-13 47.6 11.6 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.16 EHU00288.1 - 2.7e-06 26.6 16.0 6.3e-06 25.4 15.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily FecCD PF01032.18 EHU00289.1 - 2.5e-86 289.5 31.9 3.1e-86 289.2 31.9 1.0 1 0 0 1 1 1 1 FecCD transport family DUF1294 PF06961.13 EHU00289.1 - 0.053 13.8 0.1 0.053 13.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1294) Peptidase_U4 PF03419.13 EHU00289.1 - 0.71 9.1 10.6 0.51 9.6 8.5 2.0 1 1 1 2 2 2 0 Sporulation factor SpoIIGA DUF543 PF04418.12 EHU00289.1 - 3.8 7.6 5.4 2.3 8.3 1.0 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF543) Peripla_BP_2 PF01497.18 EHU00290.1 - 1.9e-23 83.3 0.0 2.4e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein ABC_tran PF00005.27 EHU00291.1 - 2.3e-26 93.0 0.0 4.1e-26 92.1 0.0 1.4 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 EHU00291.1 - 1.6e-09 38.1 0.5 5.6e-05 23.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EHU00291.1 - 8.8e-09 35.1 0.0 1.3e-07 31.3 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EHU00291.1 - 1.1e-07 32.4 0.3 1.9e-07 31.6 0.3 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EHU00291.1 - 9e-05 23.1 0.0 0.00014 22.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EHU00291.1 - 0.00011 21.9 0.0 0.00018 21.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 EHU00291.1 - 0.00025 21.5 0.0 0.0014 19.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EHU00291.1 - 0.00044 20.5 0.1 0.0024 18.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EHU00291.1 - 0.00051 20.4 0.0 0.00084 19.7 0.0 1.3 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 EHU00291.1 - 0.00076 19.4 0.1 0.0016 18.4 0.1 1.8 1 1 0 1 1 1 1 NACHT domain AAA_5 PF07728.14 EHU00291.1 - 0.0012 18.8 0.1 0.012 15.6 0.0 2.4 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EHU00291.1 - 0.0013 18.5 0.0 0.12 12.1 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_15 PF13175.6 EHU00291.1 - 0.0061 16.3 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain SbcCD_C PF13558.6 EHU00291.1 - 0.007 16.6 0.0 0.046 13.9 0.0 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 EHU00291.1 - 0.0087 16.2 0.0 0.027 14.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EHU00291.1 - 0.018 14.8 0.0 0.095 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 EHU00291.1 - 0.02 15.1 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 EHU00291.1 - 0.024 14.2 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 EHU00291.1 - 0.025 13.6 0.0 0.048 12.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 EHU00291.1 - 0.03 13.8 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_27 PF13514.6 EHU00291.1 - 0.036 13.7 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EHU00291.1 - 0.04 13.9 0.0 0.2 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EHU00291.1 - 0.045 13.7 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 EHU00291.1 - 0.067 13.1 0.1 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1 PF01926.23 EHU00291.1 - 0.074 13.1 0.0 0.21 11.7 0.0 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.6 EHU00291.1 - 0.089 13.0 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EHU00291.1 - 0.1 13.0 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.6 EHU00291.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 EHU00291.1 - 0.13 11.9 0.0 0.14 11.8 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.6 EHU00291.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 EHU00291.1 - 0.17 11.9 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRPRB PF09439.10 EHU00291.1 - 0.18 11.2 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Pox_A32 PF04665.12 EHU00291.1 - 0.19 11.2 0.0 0.41 10.1 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein HTH_Tnp_1 PF01527.20 EHU00292.1 - 9.5e-09 35.5 0.0 7.8e-08 32.5 0.0 2.1 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.6 EHU00292.1 - 0.0006 19.5 0.0 0.0079 16.0 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 EHU00292.1 - 0.017 15.0 0.1 0.31 11.0 0.0 2.2 2 0 0 2 2 2 0 MarR family HTH_28 PF13518.6 EHU00292.1 - 0.063 13.4 0.0 13 6.1 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 EHU00293.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU00293.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU00293.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU00293.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHU00294.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHU00295.1 - 3e-98 328.8 3.4 1.9e-97 326.1 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU00295.1 - 3.4e-16 59.2 0.1 1.3e-15 57.3 0.1 2.1 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU00295.1 - 1.4e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU00295.1 - 8.7e-11 42.4 9.0 1.9e-10 41.4 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Phage_HK97_TLTM PF06120.11 EHU00295.1 - 0.029 13.6 0.7 0.056 12.6 0.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein UME PF08064.13 EHU00295.1 - 0.038 13.9 0.4 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain Exonuc_VII_L PF02601.15 EHU00295.1 - 0.041 13.4 2.5 0.044 13.4 0.9 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit FUSC PF04632.12 EHU00295.1 - 0.063 11.8 7.7 0.1 11.1 7.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Csm1_N PF18504.1 EHU00295.1 - 0.13 12.7 3.4 0.86 10.0 0.2 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Tho2 PF11262.8 EHU00295.1 - 0.17 11.0 0.3 0.28 10.4 0.3 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DHR10 PF18595.1 EHU00295.1 - 0.18 11.9 10.2 0.31 11.1 10.2 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain ERM PF00769.19 EHU00295.1 - 0.28 11.0 10.4 0.45 10.3 10.4 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family LXG PF04740.12 EHU00295.1 - 0.28 10.9 2.4 0.86 9.3 0.3 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily HHH_8 PF14716.6 EHU00295.1 - 0.34 11.3 4.0 0.56 10.6 1.9 2.4 2 1 0 2 2 2 0 Helix-hairpin-helix domain Zn-ribbon_8 PF09723.10 EHU00295.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain TSNAXIP1_N PF15739.5 EHU00295.1 - 0.46 10.9 3.2 0.99 9.8 3.2 1.5 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus FAM184 PF15665.5 EHU00295.1 - 0.49 10.1 7.3 0.78 9.5 7.3 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B TMPIT PF07851.13 EHU00295.1 - 0.77 8.9 2.7 1.2 8.4 2.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein CREPT PF16566.5 EHU00295.1 - 2.3 8.4 8.3 1.1 9.5 5.2 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour HAUS-augmin3 PF14932.6 EHU00295.1 - 2.5 7.6 7.4 5.8 6.4 7.4 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 SlyX PF04102.12 EHU00295.1 - 8.1 7.2 8.7 17 6.1 2.1 3.0 1 1 1 2 2 2 0 SlyX AMNp_N PF10423.9 EHU00296.1 - 2.1e-52 176.9 0.0 3.4e-52 176.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial AMP nucleoside phosphorylase N-terminus PNP_UDP_1 PF01048.20 EHU00296.1 - 2.4e-17 63.0 0.0 4.2e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily XhlA PF10779.9 EHU00297.1 - 1.2e-10 41.4 2.1 0.0026 17.9 0.8 4.3 1 1 4 5 5 5 4 Haemolysin XhlA UPF0184 PF03670.13 EHU00297.1 - 4.7e-09 36.5 14.0 0.5 10.8 0.2 5.1 1 1 5 6 6 6 4 Uncharacterised protein family (UPF0184) NPV_P10 PF05531.12 EHU00297.1 - 1.2e-07 32.1 0.0 0.062 13.8 0.0 3.5 1 1 1 2 2 2 2 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.7 EHU00297.1 - 3.3e-07 30.5 0.0 2.1e-05 24.7 0.0 2.1 1 1 1 2 2 2 2 Tropomyosin like DUF1664 PF07889.12 EHU00297.1 - 4.5e-07 29.9 0.0 0.002 18.2 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) V-SNARE_C PF12352.8 EHU00297.1 - 1.2e-06 28.6 0.4 3.1 8.1 0.0 4.9 1 1 6 7 7 7 1 Snare region anchored in the vesicle membrane C-terminus Matrilin_ccoil PF10393.9 EHU00297.1 - 1.4e-06 28.0 0.0 3.1 7.7 0.0 5.2 1 1 3 5 5 5 1 Trimeric coiled-coil oligomerisation domain of matrilin Tropomyosin PF00261.20 EHU00297.1 - 3.1e-06 26.7 0.0 3.9e-06 26.4 0.0 1.0 1 0 0 1 1 1 1 Tropomyosin DUF16 PF01519.16 EHU00297.1 - 4.8e-06 27.0 1.4 0.062 13.8 0.1 4.0 1 1 2 3 3 3 1 Protein of unknown function DUF16 FlaC_arch PF05377.11 EHU00297.1 - 4e-05 23.9 0.0 4.5 7.8 0.0 3.6 1 1 3 4 4 4 0 Flagella accessory protein C (FlaC) DUF2802 PF10975.8 EHU00297.1 - 5.3e-05 23.3 0.0 9.7 6.4 0.0 4.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2802) E2R135 PF11570.8 EHU00297.1 - 6.5e-05 23.2 0.0 1.1 9.6 0.0 3.3 1 1 3 4 4 4 2 Coiled-coil receptor-binding R-domain of colicin E2 MtrG PF04210.13 EHU00297.1 - 8.5e-05 22.3 7.5 9 6.2 0.5 6.5 1 1 6 7 7 7 0 Tetrahydromethanopterin S-methyltransferase, subunit G CLZ PF16526.5 EHU00297.1 - 0.00018 21.8 0.1 3.2 8.2 0.0 4.1 1 1 1 2 2 2 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Snapin_Pallidin PF14712.6 EHU00297.1 - 0.00025 21.4 0.0 0.53 10.7 0.0 3.7 1 1 2 3 3 3 1 Snapin/Pallidin Baculo_PEP_C PF04513.12 EHU00297.1 - 0.00041 20.4 0.0 0.042 13.9 0.0 2.3 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus CCDC-167 PF15188.6 EHU00297.1 - 0.00073 19.8 0.3 31 5.0 0.0 4.5 1 1 4 5 5 5 0 Coiled-coil domain-containing protein 167 Glyco_H_20C_C PF18088.1 EHU00297.1 - 0.00081 19.3 11.7 10 5.9 0.2 5.5 1 1 4 5 5 5 0 Glycoside Hydrolase 20C C-terminal domain DUF3552 PF12072.8 EHU00297.1 - 0.00089 18.7 0.1 0.47 9.8 0.1 2.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3552) Laminin_II PF06009.12 EHU00297.1 - 0.0012 18.8 0.0 0.063 13.3 0.0 2.1 1 1 1 2 2 2 1 Laminin Domain II EzrA PF06160.12 EHU00297.1 - 0.0013 17.0 0.0 0.4 8.8 0.0 2.0 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA DUF4164 PF13747.6 EHU00297.1 - 0.0025 18.0 5.6 0.5 10.7 0.7 2.8 1 1 1 2 2 2 2 Domain of unknown function (DUF4164) Myosin_tail_1 PF01576.19 EHU00297.1 - 0.0042 15.0 0.0 0.005 14.7 0.0 1.0 1 0 0 1 1 1 1 Myosin tail Occludin_ELL PF07303.13 EHU00297.1 - 0.0075 17.0 0.0 1.1 10.1 0.0 2.9 1 1 0 1 1 1 1 Occludin homology domain Exonuc_VII_L PF02601.15 EHU00297.1 - 0.0093 15.6 0.0 0.018 14.6 0.0 1.5 1 1 0 1 1 1 1 Exonuclease VII, large subunit COG2 PF06148.11 EHU00297.1 - 0.0096 16.0 0.0 9.4 6.3 0.0 3.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF241 PF03087.14 EHU00297.1 - 0.011 15.5 0.0 8.6 6.1 0.0 3.0 1 1 1 2 2 2 0 Arabidopsis protein of unknown function DASH_Spc19 PF08287.11 EHU00297.1 - 0.026 14.4 0.0 18 5.2 0.0 3.0 1 1 3 4 4 4 0 Spc19 DUF4140 PF13600.6 EHU00297.1 - 0.029 14.8 0.0 6.7 7.2 0.0 3.3 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) ACP_PD PF04336.12 EHU00297.1 - 0.031 14.7 0.0 2.1 8.8 0.0 3.2 1 1 1 2 2 2 0 Acyl carrier protein phosphodiesterase Nup54 PF13874.6 EHU00297.1 - 0.04 14.0 0.0 0.14 12.2 0.0 1.9 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 EMP24_GP25L PF01105.24 EHU00297.1 - 0.044 13.7 0.0 0.088 12.7 0.0 1.7 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Cortex-I_coil PF09304.10 EHU00297.1 - 0.048 13.9 0.4 0.63 10.3 0.4 2.4 1 1 0 1 1 1 0 Cortexillin I, coiled coil RmuC PF02646.16 EHU00297.1 - 0.048 12.8 0.0 3.1 6.8 0.0 2.5 1 1 1 2 2 2 0 RmuC family HrpB7 PF09486.10 EHU00297.1 - 0.059 13.7 0.0 26 5.2 0.0 2.9 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) MscS_porin PF12795.7 EHU00297.1 - 0.079 12.5 0.0 0.83 9.2 0.0 2.1 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain APG17 PF04108.12 EHU00297.1 - 0.08 12.0 0.0 9.1 5.3 0.0 2.5 1 1 1 2 2 2 0 Autophagy protein Apg17 Spc7 PF08317.11 EHU00297.1 - 0.1 11.5 0.0 0.91 8.3 0.0 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein Sec3_C PF09763.9 EHU00297.1 - 0.1 11.0 0.0 9.7 4.4 0.0 2.1 1 1 1 2 2 2 0 Exocyst complex component Sec3 Osmo_CC PF08946.10 EHU00297.1 - 0.13 12.5 0.3 6.9 7.0 0.1 3.5 1 1 3 4 4 4 0 Osmosensory transporter coiled coil KxDL PF10241.9 EHU00297.1 - 0.15 12.3 0.1 53 4.2 0.1 3.2 1 1 3 4 4 4 0 Uncharacterized conserved protein GAS PF13851.6 EHU00297.1 - 0.21 10.9 0.0 0.74 9.1 0.0 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Hemagglutinin PF00509.18 EHU00297.1 - 0.51 8.7 0.7 6.9 5.0 0.1 2.3 1 1 1 2 2 2 0 Haemagglutinin DUF1283 PF06932.11 EHU00297.1 - 5.5 7.3 6.9 41 4.5 5.5 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1283) TraF_2 PF13729.6 EHU00297.1 - 8.4 5.7 15.2 1.4 8.2 1.7 2.7 1 1 1 2 2 2 0 F plasmid transfer operon, TraF, protein DDE_3 PF13358.6 EHU00298.1 - 1.1e-22 80.3 0.0 1.9e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 EHU00298.1 - 1.1e-10 41.0 1.0 3.6e-09 36.2 0.1 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 EHU00298.1 - 4.1e-09 36.9 1.1 2.8e-08 34.3 0.3 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 EHU00298.1 - 4e-07 30.0 1.2 1.1e-06 28.6 0.3 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHU00298.1 - 1.4e-05 25.1 0.3 0.0002 21.4 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_33 PF13592.6 EHU00298.1 - 6e-05 22.6 5.4 8.3e-05 22.1 0.5 3.0 3 0 0 3 3 3 1 Winged helix-turn helix LZ_Tnp_IS481 PF13011.6 EHU00298.1 - 0.029 14.9 0.2 0.061 13.8 0.2 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 HTH_38 PF13936.6 EHU00298.1 - 0.052 13.3 0.6 0.16 11.8 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain Xan_ur_permease PF00860.20 EHU00300.1 - 1.8e-56 191.5 46.1 2.5e-56 191.1 46.1 1.2 1 0 0 1 1 1 1 Permease family Response_reg PF00072.24 EHU00301.1 - 5.4e-24 84.5 0.9 7.2e-24 84.1 0.3 1.5 2 0 0 2 2 2 1 Response regulator receiver domain Trans_reg_C PF00486.28 EHU00301.1 - 1.9e-22 79.1 0.3 1.9e-22 79.1 0.3 1.7 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal PfkB PF00294.24 EHU00302.1 - 2.6e-35 122.2 0.0 4.6e-35 121.4 0.0 1.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Hairy_orange PF07527.13 EHU00302.1 - 0.093 13.0 0.2 0.33 11.2 0.1 2.0 2 0 0 2 2 2 0 Hairy Orange F_bP_aldolase PF01116.20 EHU00303.1 - 1.3e-94 316.8 0.1 1.4e-94 316.7 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II AP_endonuc_2 PF01261.24 EHU00303.1 - 0.0042 16.5 0.2 0.02 14.3 0.1 2.0 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel FMN_dh PF01070.18 EHU00303.1 - 0.0055 15.8 0.0 0.0079 15.3 0.0 1.4 1 1 0 1 1 1 1 FMN-dependent dehydrogenase DSBA PF01323.20 EHU00303.1 - 0.03 14.1 0.1 1.2 8.9 0.0 2.4 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Peripla_BP_5 PF13433.6 EHU00303.1 - 0.1 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein domain Lyx_isomer PF07385.12 EHU00304.1 - 2.5e-91 304.9 0.0 2.8e-91 304.8 0.0 1.0 1 0 0 1 1 1 1 D-lyxose isomerase Cupin_2 PF07883.11 EHU00304.1 - 0.0072 16.0 0.5 1.8 8.3 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Peripla_BP_4 PF13407.6 EHU00305.1 - 1.2e-54 185.6 11.1 1.4e-54 185.4 11.1 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 EHU00305.1 - 2.8e-19 69.6 1.0 4.2e-19 69.0 0.4 1.4 2 0 0 2 2 2 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 EHU00305.1 - 6.7e-08 33.0 0.1 3.4e-07 30.7 0.0 2.0 1 1 1 2 2 2 1 Periplasmic binding protein-like domain Toprim_2 PF13155.6 EHU00305.1 - 0.11 13.0 0.6 1.5 9.3 0.1 2.5 2 1 0 2 2 2 0 Toprim-like BPD_transp_2 PF02653.16 EHU00306.1 - 1.8e-42 145.3 49.1 3e-42 144.6 49.1 1.3 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component ABC_tran PF00005.27 EHU00307.1 - 7.4e-56 188.4 0.2 2.8e-32 112.1 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EHU00307.1 - 3.8e-09 36.8 0.4 0.01 15.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EHU00307.1 - 3.3e-05 23.7 2.0 8.2e-05 22.4 0.5 2.3 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.19 EHU00307.1 - 0.00021 20.8 0.4 0.0045 16.4 0.2 2.6 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EHU00307.1 - 0.0005 20.0 1.3 0.019 14.8 0.1 3.0 3 0 0 3 3 3 1 RsgA GTPase TniB PF05621.11 EHU00307.1 - 0.0028 17.1 1.1 0.069 12.6 0.4 2.8 3 0 0 3 3 3 1 Bacterial TniB protein AAA_29 PF13555.6 EHU00307.1 - 0.0031 17.2 0.2 0.012 15.4 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_27 PF13514.6 EHU00307.1 - 0.0059 16.2 0.0 0.017 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EHU00307.1 - 0.009 15.3 0.1 0.63 9.3 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 EHU00307.1 - 0.021 15.2 2.2 0.63 10.4 0.6 2.7 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 EHU00307.1 - 0.022 15.0 2.4 0.33 11.2 1.2 3.0 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EHU00307.1 - 0.03 14.8 0.0 0.059 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EHU00307.1 - 0.033 14.2 0.4 0.97 9.4 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 EHU00307.1 - 0.039 12.9 0.6 0.42 9.5 0.0 2.6 3 0 0 3 3 3 0 AAA-like domain MMR_HSR1 PF01926.23 EHU00307.1 - 0.042 13.9 0.0 0.52 10.4 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.29 EHU00307.1 - 0.045 14.2 4.3 4.4 7.7 2.9 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 EHU00307.1 - 0.062 13.6 0.4 11 6.4 0.0 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.23 EHU00307.1 - 0.09 12.8 0.0 0.42 10.6 0.1 2.1 2 1 0 2 2 2 0 Dynamin family AAA_25 PF13481.6 EHU00307.1 - 0.11 12.1 0.5 0.51 9.9 0.1 2.2 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 EHU00307.1 - 0.14 12.0 0.4 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_18 PF13238.6 EHU00307.1 - 0.16 12.5 0.2 6.6 7.3 0.1 2.9 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EHU00307.1 - 0.32 11.2 2.4 3.5 7.8 2.4 2.8 1 1 0 1 1 1 0 AAA domain HATPase_c PF02518.26 EHU00308.1 - 8.9e-23 80.9 0.0 1.6e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EHU00308.1 - 7.9e-12 45.3 0.0 2e-11 44.0 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HAMP PF00672.25 EHU00308.1 - 4.9e-10 39.6 0.1 4.9e-10 39.6 0.1 2.6 2 0 0 2 2 2 1 HAMP domain PAS_7 PF12860.7 EHU00308.1 - 7.5e-10 39.0 0.2 2.6e-06 27.6 0.0 3.5 2 1 1 3 3 3 2 PAS fold HisKA PF00512.25 EHU00308.1 - 5.2e-06 26.4 0.1 5.2e-06 26.4 0.1 2.9 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 EHU00308.1 - 0.006 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase JAKMIP_CC3 PF16034.5 EHU00308.1 - 0.058 13.3 1.1 0.16 11.9 1.1 1.7 1 0 0 1 1 1 0 JAKMIP CC3 domain BPD_transp_1 PF00528.22 EHU00309.1 - 9.2e-08 32.0 6.2 9.2e-08 32.0 6.2 2.2 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 EHU00310.1 - 1.5e-16 60.7 7.7 1.5e-16 60.7 7.7 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component YuiB PF14068.6 EHU00310.1 - 0.088 13.4 2.8 0.22 12.1 0.8 2.5 3 0 0 3 3 3 0 Putative membrane protein SLATT_1 PF18181.1 EHU00310.1 - 0.53 10.2 0.1 0.53 10.2 0.1 2.7 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 Phosphonate-bd PF12974.7 EHU00311.1 - 5.6e-49 166.9 0.0 6.8e-49 166.7 0.0 1.0 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 EHU00311.1 - 0.00047 20.2 0.0 0.0009 19.2 0.0 1.4 1 0 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.20 EHU00311.1 - 0.0024 17.3 0.0 0.0048 16.3 0.0 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Rhamnogal_lyase PF06045.11 EHU00311.1 - 0.099 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Rhamnogalacturonate lyase family ABC_tran PF00005.27 EHU00312.1 - 2.2e-33 115.7 0.0 4e-33 114.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EHU00312.1 - 4.5e-07 30.0 0.1 0.00063 19.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EHU00312.1 - 1.6e-05 24.9 1.3 9.6e-05 22.3 0.5 2.1 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 EHU00312.1 - 3.4e-05 23.4 0.8 0.00016 21.2 0.7 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EHU00312.1 - 0.00065 19.4 0.1 0.0021 17.8 0.1 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EHU00312.1 - 0.00072 20.0 0.1 0.0019 18.6 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain KdpD PF02702.17 EHU00312.1 - 0.0024 17.4 0.0 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 Osmosensitive K+ channel His kinase sensor domain AAA_15 PF13175.6 EHU00312.1 - 0.0064 16.2 0.0 0.59 9.8 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EHU00312.1 - 0.0066 16.7 0.1 0.015 15.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EHU00312.1 - 0.007 16.4 0.1 0.016 15.3 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_30 PF13604.6 EHU00312.1 - 0.018 14.7 0.1 0.044 13.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 EHU00312.1 - 0.028 14.1 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.6 EHU00312.1 - 0.034 14.4 0.1 1.2 9.4 0.0 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 EHU00312.1 - 0.086 12.4 0.1 0.13 11.8 0.1 1.4 1 1 0 1 1 1 0 AAA domain EF-hand_3 PF09069.11 EHU00312.1 - 0.093 13.1 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 EF-hand AAA_23 PF13476.6 EHU00312.1 - 0.096 13.2 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EHU00312.1 - 0.11 12.4 0.1 0.26 11.2 0.1 1.6 1 0 0 1 1 1 0 NACHT domain Cellulase PF00150.18 EHU00312.1 - 0.12 11.8 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Zeta_toxin PF06414.12 EHU00312.1 - 0.14 11.4 0.0 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DnaB_C PF03796.15 EHU00312.1 - 0.15 11.4 0.2 0.35 10.2 0.0 1.7 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Lactamase_B_2 PF12706.7 EHU00313.1 - 4.2e-19 68.9 0.3 6.5e-19 68.2 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EHU00313.1 - 5.5e-09 36.3 0.0 8.4e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 EHU00313.1 - 0.024 14.5 0.0 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 Beta-lactamase superfamily domain DUF1922 PF09082.10 EHU00313.1 - 0.082 13.2 0.1 0.14 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1922) Guanylate_kin PF00625.21 EHU00314.1 - 3e-08 33.6 0.0 3.6e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.6 EHU00314.1 - 4e-07 30.6 0.0 5.9e-06 26.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EHU00314.1 - 3.5e-06 27.3 0.1 2.6e-05 24.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EHU00314.1 - 0.027 14.9 0.7 0.19 12.1 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 EHU00314.1 - 0.046 13.5 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EHU00314.1 - 0.091 13.0 0.0 0.24 11.7 0.0 1.8 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EHU00314.1 - 0.21 11.5 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 EHU00315.1 - 3.3e-27 95.7 0.0 4.3e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EHU00315.1 - 9e-08 32.7 0.0 1.2e-07 32.3 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EHU00315.1 - 1.1e-05 25.3 0.0 1.8e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 EHU00315.1 - 1.3e-05 24.7 0.0 0.0083 15.6 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EHU00315.1 - 3.4e-05 23.8 0.0 0.079 12.8 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 EHU00315.1 - 0.00028 21.0 0.6 0.00073 19.7 0.6 1.9 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EHU00315.1 - 0.00029 20.5 0.0 0.00054 19.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EHU00315.1 - 0.00032 21.0 0.0 0.00059 20.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EHU00315.1 - 0.005 16.6 0.0 0.012 15.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EHU00315.1 - 0.0074 16.4 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_23 PF13476.6 EHU00315.1 - 0.0099 16.4 0.0 0.015 15.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 EHU00315.1 - 0.013 14.7 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.12 EHU00315.1 - 0.017 15.1 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 EHU00315.1 - 0.034 13.9 0.1 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein NB-ARC PF00931.22 EHU00315.1 - 0.044 13.0 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_28 PF13521.6 EHU00315.1 - 0.046 14.0 0.0 0.083 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain CPT PF07931.12 EHU00315.1 - 0.069 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein cobW PF02492.19 EHU00315.1 - 0.077 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 EHU00315.1 - 0.078 13.5 0.0 0.14 12.7 0.0 1.6 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 EHU00315.1 - 0.097 12.7 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FtsK_SpoIIIE PF01580.18 EHU00315.1 - 0.097 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_25 PF13481.6 EHU00315.1 - 0.1 12.2 0.0 0.23 11.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EHU00315.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 EHU00315.1 - 0.17 12.3 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 EHU00316.1 - 4.9e-32 111.3 0.0 6.7e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EHU00316.1 - 2.2e-08 34.3 0.0 0.00034 20.5 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system oligo_HPY PF08352.12 EHU00316.1 - 9.2e-06 26.1 0.0 1.6e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_16 PF13191.6 EHU00316.1 - 1.2e-05 25.8 0.3 2.1e-05 25.0 0.3 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EHU00316.1 - 0.00016 22.0 0.4 0.0013 19.0 0.4 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EHU00316.1 - 0.00022 20.9 0.0 0.00051 19.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.12 EHU00316.1 - 0.00089 19.2 0.1 0.0039 17.1 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_23 PF13476.6 EHU00316.1 - 0.00091 19.8 0.0 0.0014 19.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EHU00316.1 - 0.001 18.7 1.5 0.014 15.0 1.5 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EHU00316.1 - 0.0028 17.8 0.1 0.0066 16.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain MobB PF03205.14 EHU00316.1 - 0.003 17.5 0.0 0.0053 16.7 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B RsgA_GTPase PF03193.16 EHU00316.1 - 0.0066 16.4 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 EHU00316.1 - 0.011 15.5 0.2 0.036 13.8 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EHU00316.1 - 0.014 15.1 0.0 2.1 7.9 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.14 EHU00316.1 - 0.015 15.3 0.1 0.046 13.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) cobW PF02492.19 EHU00316.1 - 0.017 14.7 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TniB PF05621.11 EHU00316.1 - 0.025 14.0 0.0 4.8 6.5 0.1 2.3 2 0 0 2 2 2 0 Bacterial TniB protein SbcCD_C PF13558.6 EHU00316.1 - 0.025 14.8 0.0 0.051 13.8 0.0 1.5 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 EHU00316.1 - 0.028 13.7 0.1 0.078 12.3 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.23 EHU00316.1 - 0.031 14.3 0.0 0.092 12.8 0.0 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase PRK PF00485.18 EHU00316.1 - 0.031 14.0 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Pox_A32 PF04665.12 EHU00316.1 - 0.033 13.6 0.2 0.068 12.6 0.0 1.5 2 0 0 2 2 1 0 Poxvirus A32 protein AAA_18 PF13238.6 EHU00316.1 - 0.035 14.7 0.0 0.076 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EHU00316.1 - 0.042 14.1 0.1 0.26 11.5 0.0 2.1 2 1 1 3 3 3 0 AAA domain DUF87 PF01935.17 EHU00316.1 - 0.053 13.6 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA PF00004.29 EHU00316.1 - 0.058 13.8 0.0 0.62 10.5 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EHU00316.1 - 0.07 13.0 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain Propep_M14 PF02244.16 EHU00316.1 - 0.071 13.5 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Carboxypeptidase activation peptide SMC_N PF02463.19 EHU00316.1 - 0.074 12.5 0.0 2.1 7.7 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain NB-ARC PF00931.22 EHU00316.1 - 0.09 11.9 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF2813 PF11398.8 EHU00316.1 - 0.098 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) AAA_24 PF13479.6 EHU00316.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EHU00316.1 - 0.16 12.4 0.0 0.42 11.0 0.0 1.7 2 0 0 2 2 1 0 RNA helicase Roc PF08477.13 EHU00316.1 - 0.16 12.2 0.0 0.28 11.4 0.0 1.5 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 EHU00316.1 - 0.16 12.3 0.1 0.9 9.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EHU00316.1 - 0.17 11.9 0.0 0.62 10.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 EHU00316.1 - 0.22 10.8 0.0 0.34 10.1 0.0 1.3 1 0 0 1 1 1 0 Septin PhnJ PF06007.11 EHU00317.1 - 3e-147 488.9 0.1 3.5e-147 488.7 0.1 1.0 1 0 0 1 1 1 1 Phosphonate metabolism protein PhnJ PhnA_Zn_Ribbon PF08274.12 EHU00317.1 - 0.067 13.2 0.8 0.14 12.1 0.5 1.6 2 0 0 2 2 2 0 PhnA Zinc-Ribbon PhnI PF05861.12 EHU00318.1 - 2.2e-155 516.8 0.0 2.6e-155 516.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial phosphonate metabolism protein (PhnI) PhnG PF06754.12 EHU00318.1 - 8e-07 29.1 0.0 1.4e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Phosphonate metabolism protein PhnG PhnH PF05845.12 EHU00319.1 - 4.3e-61 206.0 0.6 4.8e-61 205.8 0.6 1.0 1 0 0 1 1 1 1 Bacterial phosphonate metabolism protein (PhnH) PhnG PF06754.12 EHU00320.1 - 1.2e-53 180.9 0.8 1.3e-53 180.7 0.8 1.0 1 0 0 1 1 1 1 Phosphonate metabolism protein PhnG UTRA PF07702.13 EHU00321.1 - 2.6e-31 108.3 0.0 3.8e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 UTRA domain GntR PF00392.21 EHU00321.1 - 1.1e-18 66.6 0.3 2.7e-18 65.4 0.3 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 EHU00321.1 - 0.00016 21.5 0.2 0.00051 20.0 0.1 2.0 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_DeoR PF08220.12 EHU00321.1 - 0.00018 21.2 0.1 0.00066 19.4 0.1 1.9 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain Rrf2 PF02082.20 EHU00321.1 - 0.0013 19.0 0.0 0.0033 17.7 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulator MarR PF01047.22 EHU00321.1 - 0.0017 18.2 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_36 PF13730.6 EHU00321.1 - 0.0068 16.3 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 EHU00321.1 - 0.0099 15.7 0.1 0.052 13.4 0.0 2.2 2 0 0 2 2 2 1 MarR family HTH_23 PF13384.6 EHU00321.1 - 0.038 13.8 1.3 1.5 8.7 0.0 3.5 4 0 0 4 4 4 0 Homeodomain-like domain HTH_11 PF08279.12 EHU00321.1 - 0.058 13.3 0.0 0.25 11.3 0.0 2.0 2 0 0 2 2 2 0 HTH domain adh_short PF00106.25 EHU00322.1 - 1.8e-50 171.1 0.0 2.6e-50 170.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EHU00322.1 - 1.5e-39 135.9 0.2 1.9e-39 135.6 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EHU00322.1 - 3.1e-12 46.8 0.0 4.4e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EHU00322.1 - 4.5e-06 26.7 3.9 8.1e-06 25.8 1.5 2.0 1 1 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EHU00322.1 - 0.0023 17.4 0.4 0.0093 15.5 0.4 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EHU00322.1 - 0.008 15.3 0.1 0.014 14.5 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain DFP PF04127.15 EHU00322.1 - 0.042 13.7 0.1 0.068 13.0 0.1 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein MTES_1575 PF18741.1 EHU00322.1 - 0.074 13.2 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 REase_MTES_1575 TPP_enzyme_N PF02776.18 EHU00323.1 - 2.4e-43 147.7 3.7 7.1e-43 146.2 0.3 2.6 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EHU00323.1 - 2.6e-30 105.2 0.0 6.6e-30 103.9 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EHU00323.1 - 2.8e-28 98.4 0.1 6.7e-28 97.1 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 EHU00323.1 - 0.0014 18.4 1.4 0.0024 17.7 1.4 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg HTH_24 PF13412.6 EHU00324.1 - 1.2e-18 66.4 0.1 1.8e-18 65.8 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding AsnC_trans_reg PF01037.21 EHU00324.1 - 2.3e-18 65.9 0.1 3.4e-18 65.4 0.1 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_AsnC-type PF13404.6 EHU00324.1 - 1e-16 60.5 0.1 1.5e-16 60.0 0.1 1.2 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain MarR PF01047.22 EHU00324.1 - 0.00026 20.8 0.0 0.00051 19.9 0.0 1.4 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 EHU00324.1 - 0.011 15.6 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_20 PF12840.7 EHU00324.1 - 0.029 14.4 0.0 0.05 13.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_CodY PF08222.11 EHU00324.1 - 0.069 12.7 0.0 0.3 10.7 0.0 2.0 1 1 1 2 2 2 0 CodY helix-turn-helix domain HemN_C PF06969.16 EHU00324.1 - 0.097 12.8 0.0 1.3 9.2 0.0 2.4 1 1 0 1 1 1 0 HemN C-terminal domain HTH_Crp_2 PF13545.6 EHU00324.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Rrf2 PF02082.20 EHU00324.1 - 0.15 12.4 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator Aminotran_3 PF00202.21 EHU00325.1 - 1.4e-127 425.7 0.0 1.7e-127 425.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EHU00325.1 - 0.00047 19.4 0.0 0.0066 15.7 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II Peptidase_M20 PF01546.28 EHU00326.1 - 6.4e-29 101.1 0.2 7.7e-29 100.9 0.2 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EHU00326.1 - 4e-09 36.4 0.1 9.8e-09 35.1 0.1 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain BAG6 PF12057.8 EHU00326.1 - 0.043 13.5 0.4 0.41 10.3 0.1 2.3 2 0 0 2 2 2 0 BCL2-associated athanogene 6 2-Hacid_dh_C PF02826.19 EHU00327.1 - 1e-43 148.8 0.0 1.3e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EHU00327.1 - 0.0049 17.1 0.0 0.0073 16.5 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh PF00389.30 EHU00327.1 - 0.034 13.8 0.0 0.041 13.5 0.0 1.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Acetyltransf_18 PF18014.1 EHU00328.1 - 8.5e-23 80.5 0.0 9.2e-20 70.7 0.0 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EHU00328.1 - 9.9e-12 44.9 0.1 1.8e-10 40.9 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EHU00328.1 - 5.1e-11 42.9 0.2 1.2e-10 41.7 0.2 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EHU00328.1 - 1e-10 41.9 0.0 2.1e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EHU00328.1 - 1.2e-05 25.1 0.3 6.5e-05 22.8 0.3 2.2 2 1 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.7 EHU00328.1 - 0.00011 22.2 0.0 0.0022 18.1 0.0 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EHU00328.1 - 0.001 19.7 0.9 0.0046 17.6 0.5 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EHU00328.1 - 0.059 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DAO PF01266.24 EHU00329.1 - 3.5e-64 217.6 3.1 4.9e-64 217.1 3.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EHU00329.1 - 7.4e-08 31.9 0.8 2.5e-06 26.8 0.3 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EHU00329.1 - 2.1e-07 30.4 9.1 3.9e-06 26.2 9.1 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EHU00329.1 - 4.4e-07 30.0 0.1 1.4e-06 28.4 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EHU00329.1 - 6e-07 29.0 0.6 4.8e-06 26.0 0.1 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 EHU00329.1 - 1e-06 28.2 0.4 5e-06 26.0 0.4 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EHU00329.1 - 0.00018 21.0 3.3 0.00029 20.3 3.3 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EHU00329.1 - 0.00037 19.9 0.6 0.0007 18.9 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 EHU00329.1 - 0.0015 17.9 0.0 0.0032 16.8 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 EHU00329.1 - 0.0019 17.3 1.0 0.0021 17.2 0.2 1.4 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EHU00329.1 - 0.0046 16.3 1.0 0.034 13.4 0.3 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EHU00329.1 - 0.006 15.3 1.8 0.006 15.3 1.8 2.0 2 0 0 2 2 2 1 HI0933-like protein ApbA PF02558.16 EHU00329.1 - 0.031 13.9 0.1 0.053 13.2 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EHU00329.1 - 0.054 13.4 1.5 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ATP-synt_ab_Xtn PF16886.5 EHU00329.1 - 0.2 11.5 0.0 24 4.8 0.0 2.3 1 1 1 2 2 2 0 ATPsynthase alpha/beta subunit N-term extension Trp_halogenase PF04820.14 EHU00329.1 - 0.41 9.4 2.1 0.62 8.8 2.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase ABC_tran PF00005.27 EHU00330.1 - 9.6e-53 178.4 0.0 1.4e-26 93.6 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EHU00330.1 - 8.9e-14 52.0 3.3 0.0053 16.6 0.0 4.2 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EHU00330.1 - 2.5e-08 33.7 3.6 0.00049 19.6 0.2 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EHU00330.1 - 2.7e-08 34.2 2.1 0.019 15.3 0.2 4.0 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EHU00330.1 - 5.8e-08 33.3 1.9 0.012 16.0 0.2 2.9 2 2 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 EHU00330.1 - 8.9e-08 32.6 0.3 0.11 12.9 0.0 3.7 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 EHU00330.1 - 1.4e-07 31.1 0.5 0.024 14.4 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.12 EHU00330.1 - 5.9e-07 29.5 1.6 0.0099 15.8 0.2 2.5 2 1 0 2 2 2 2 NACHT domain RsgA_GTPase PF03193.16 EHU00330.1 - 1.2e-06 28.5 1.3 0.093 12.6 0.0 3.8 3 1 1 4 4 3 2 RsgA GTPase AAA_5 PF07728.14 EHU00330.1 - 2.7e-06 27.4 3.2 0.15 12.1 0.3 4.1 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.25 EHU00330.1 - 7e-06 25.8 2.5 0.032 13.9 0.0 2.4 2 1 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.6 EHU00330.1 - 7.7e-06 26.5 0.1 0.054 14.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.6 EHU00330.1 - 8.1e-06 26.5 1.1 0.1 13.1 0.3 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EHU00330.1 - 1e-05 25.2 7.6 0.027 14.1 0.1 4.2 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 EHU00330.1 - 2e-05 24.4 4.5 0.063 13.0 0.1 3.3 4 0 0 4 4 3 2 IstB-like ATP binding protein AAA_24 PF13479.6 EHU00330.1 - 4.4e-05 23.3 1.0 0.14 11.9 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.6 EHU00330.1 - 4.8e-05 23.5 4.9 0.22 11.7 0.8 3.8 2 2 0 2 2 2 2 AAA domain APS_kinase PF01583.20 EHU00330.1 - 7e-05 22.8 0.1 0.15 12.0 0.0 2.6 2 0 0 2 2 2 2 Adenylylsulphate kinase PhoH PF02562.16 EHU00330.1 - 0.00012 21.6 0.3 0.51 9.7 0.1 2.4 2 0 0 2 2 2 2 PhoH-like protein Roc PF08477.13 EHU00330.1 - 0.00012 22.3 0.0 0.65 10.2 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase CbiA PF01656.23 EHU00330.1 - 0.00012 22.1 0.5 0.088 12.9 0.0 3.0 3 0 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain Mg_chelatase PF01078.21 EHU00330.1 - 0.00013 21.5 0.2 0.049 13.0 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI PRK PF00485.18 EHU00330.1 - 0.00024 20.9 0.4 0.22 11.3 0.0 2.7 3 0 0 3 3 2 1 Phosphoribulokinase / Uridine kinase family MobB PF03205.14 EHU00330.1 - 0.00026 20.9 0.8 1.3 8.9 0.1 3.1 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.6 EHU00330.1 - 0.0003 21.1 0.9 2.6 8.3 0.0 3.6 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.22 EHU00330.1 - 0.00035 19.9 0.4 0.35 10.0 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain Sigma54_activat PF00158.26 EHU00330.1 - 0.00041 20.1 0.4 0.58 9.9 0.1 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain PduV-EutP PF10662.9 EHU00330.1 - 0.00041 20.1 1.2 0.54 10.0 0.0 2.9 3 0 0 3 3 2 2 Ethanolamine utilisation - propanediol utilisation TIP49 PF06068.13 EHU00330.1 - 0.00046 19.5 0.6 0.63 9.2 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain TniB PF05621.11 EHU00330.1 - 0.00051 19.5 1.1 11 5.4 0.0 4.2 4 0 0 4 4 4 0 Bacterial TniB protein ATPase PF06745.13 EHU00330.1 - 0.00072 19.0 7.5 2 7.7 0.1 4.8 4 1 1 5 5 5 2 KaiC AAA_7 PF12775.7 EHU00330.1 - 0.00073 19.1 0.1 1.4 8.4 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region TsaE PF02367.17 EHU00330.1 - 0.00074 19.5 0.2 1.1 9.3 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_15 PF13175.6 EHU00330.1 - 0.001 18.9 0.0 0.49 10.0 0.0 2.4 3 0 0 3 3 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 EHU00330.1 - 0.0021 18.1 0.0 1.1 9.4 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase oligo_HPY PF08352.12 EHU00330.1 - 0.0033 17.9 0.0 0.11 13.1 0.0 2.4 2 0 0 2 2 2 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_19 PF13245.6 EHU00330.1 - 0.005 17.2 3.2 3.4 8.0 1.3 3.0 2 2 0 2 2 2 0 AAA domain T2SSE PF00437.20 EHU00330.1 - 0.0067 15.5 0.0 3.1 6.8 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein RNA_helicase PF00910.22 EHU00330.1 - 0.0075 16.6 0.1 6 7.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase cobW PF02492.19 EHU00330.1 - 0.0077 15.8 0.2 6.4 6.3 0.0 3.2 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 EHU00330.1 - 0.0084 15.8 6.2 1.9 8.1 0.0 3.4 2 2 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 EHU00330.1 - 0.011 15.7 0.6 2.8 7.8 0.0 3.2 3 0 0 3 3 3 0 NTPase DEAD PF00270.29 EHU00330.1 - 0.018 14.8 0.1 9.8 5.9 0.0 2.8 2 2 0 2 2 2 0 DEAD/DEAH box helicase RecA PF00154.21 EHU00330.1 - 0.032 13.7 0.1 7.9 5.9 0.0 2.5 2 0 0 2 2 2 0 recA bacterial DNA recombination protein CPT PF07931.12 EHU00330.1 - 0.04 13.8 0.3 13 5.6 0.0 2.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Pox_A32 PF04665.12 EHU00330.1 - 0.042 13.3 1.6 2 7.8 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein Rad51 PF08423.11 EHU00330.1 - 0.057 12.7 0.1 8.8 5.5 0.0 2.4 2 0 0 2 2 2 0 Rad51 ATP_bind_1 PF03029.17 EHU00330.1 - 0.06 13.1 0.5 5 6.8 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.18 EHU00330.1 - 0.074 12.4 0.4 6 6.1 0.0 2.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family Sigma54_activ_2 PF14532.6 EHU00330.1 - 0.086 13.0 0.3 15 5.7 0.0 2.8 2 1 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 EHU00330.1 - 0.088 12.1 2.1 9.6 5.4 0.0 2.9 2 1 1 3 3 3 0 Zeta toxin Dynamin_N PF00350.23 EHU00330.1 - 0.1 12.7 0.5 9.4 6.3 0.1 2.9 2 1 0 2 2 2 0 Dynamin family CoaE PF01121.20 EHU00330.1 - 0.11 12.2 1.5 6.8 6.3 0.0 3.1 3 0 0 3 3 3 0 Dephospho-CoA kinase G-alpha PF00503.20 EHU00330.1 - 0.11 11.7 0.0 7.4 5.6 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit ResIII PF04851.15 EHU00330.1 - 0.12 12.4 0.1 9.3 6.2 0.0 3.0 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_13 PF13166.6 EHU00330.1 - 0.26 9.9 0.1 6.2 5.3 0.0 2.3 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.17 EHU00330.1 - 0.36 10.9 3.2 7.3 6.6 0.5 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain ABC_ATPase PF09818.9 EHU00330.1 - 4.1 6.1 13.8 0.55 9.0 0.6 4.1 4 1 0 4 4 4 0 Predicted ATPase of the ABC class BPD_transp_1 PF00528.22 EHU00331.1 - 8.6e-24 84.3 11.4 8.6e-24 84.3 11.4 2.7 1 1 1 3 3 3 2 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 EHU00331.1 - 0.046 13.7 0.1 0.046 13.7 0.1 3.6 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C BPD_transp_1 PF00528.22 EHU00332.1 - 7.6e-34 117.1 13.0 7.6e-34 117.1 13.0 1.9 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component SBP_bac_5 PF00496.22 EHU00333.1 - 3.2e-68 230.4 0.0 4e-68 230.1 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle MG4 PF17789.1 EHU00333.1 - 0.16 12.1 0.0 0.5 10.5 0.0 1.8 2 0 0 2 2 2 0 Macroglobulin domain MG4 DAO PF01266.24 EHU00334.1 - 2.6e-58 198.3 0.4 3e-58 198.1 0.4 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EHU00334.1 - 7.4e-10 38.6 0.1 0.00037 19.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EHU00334.1 - 1.6e-09 37.5 2.2 2.3e-08 33.6 1.3 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EHU00334.1 - 1.1e-08 34.2 0.3 7.9e-05 21.5 0.2 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 EHU00334.1 - 3.2e-07 29.8 3.9 5e-07 29.2 2.4 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 EHU00334.1 - 1.4e-05 24.5 0.1 2.2e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EHU00334.1 - 2.2e-05 23.7 0.4 4.1e-05 22.8 0.4 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EHU00334.1 - 3.6e-05 23.3 0.1 5.1e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EHU00334.1 - 0.00019 20.8 0.8 0.00031 20.1 0.4 1.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 EHU00334.1 - 0.00021 20.6 0.2 0.00035 19.9 0.2 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 EHU00334.1 - 0.00029 21.0 1.7 0.00029 21.0 1.7 2.5 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EHU00334.1 - 0.00064 19.1 0.1 0.044 13.1 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase 3HCDH_N PF02737.18 EHU00334.1 - 0.00088 19.2 1.4 0.0052 16.7 0.3 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 EHU00334.1 - 0.0016 18.4 1.6 0.46 10.4 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EHU00334.1 - 0.0017 17.5 0.6 0.0031 16.6 0.6 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 EHU00334.1 - 0.0025 18.3 1.3 0.012 16.2 0.6 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 EHU00334.1 - 0.0055 16.3 0.1 0.0077 15.8 0.1 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IlvN PF07991.12 EHU00334.1 - 0.048 13.2 0.5 0.08 12.5 0.5 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ThiF PF00899.21 EHU00334.1 - 0.17 11.2 0.1 0.27 10.5 0.1 1.2 1 0 0 1 1 1 0 ThiF family ScdA_N PF04405.14 EHU00334.1 - 0.17 11.6 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown function (DUF542) HAD_2 PF13419.6 EHU00335.1 - 2e-07 31.3 0.0 2.7e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EHU00335.1 - 0.002 18.4 0.0 0.021 15.1 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EHU00335.1 - 0.089 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like Aldedh PF00171.22 EHU00336.1 - 2.8e-141 471.2 0.0 3.2e-141 471.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF2917 PF11142.8 EHU00336.1 - 0.049 13.0 0.1 0.27 10.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2917) Aldedh PF00171.22 EHU00337.1 - 2.4e-168 560.4 0.1 2.7e-168 560.2 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LysR_substrate PF03466.20 EHU00338.1 - 1.4e-47 161.8 0.2 2.1e-47 161.2 0.2 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EHU00338.1 - 2.1e-13 50.0 0.1 4.8e-13 48.9 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 EHU00338.1 - 0.018 15.0 0.0 0.042 13.7 0.0 1.7 1 0 0 1 1 1 0 MarR family HTH_20 PF12840.7 EHU00338.1 - 0.021 14.9 0.2 0.062 13.4 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_24 PF13412.6 EHU00338.1 - 0.022 14.3 0.2 0.15 11.6 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 EHU00338.1 - 0.095 12.6 0.0 0.32 10.9 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_11 PF08279.12 EHU00338.1 - 0.12 12.3 0.3 0.47 10.4 0.1 2.0 2 0 0 2 2 2 0 HTH domain LysR_substrate PF03466.20 EHU00339.1 - 3.7e-34 117.9 0.9 4.5e-34 117.6 0.9 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EHU00339.1 - 2.2e-22 78.8 0.3 7.3e-22 77.1 0.3 2.0 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family NMT1_2 PF13379.6 EHU00339.1 - 0.043 13.5 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 NMT1-like family BPD_transp_2 PF02653.16 EHU00340.1 - 2.3e-45 154.8 41.9 4.2e-45 154.0 41.9 1.4 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component DUF1427 PF07235.11 EHU00340.1 - 0.56 10.2 7.6 0.11 12.4 2.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1427) C_GCAxxG_C_C PF09719.10 EHU00340.1 - 2.3 8.5 4.4 18 5.6 0.1 2.4 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) ABC_tran PF00005.27 EHU00341.1 - 5e-59 198.7 0.0 5.3e-34 117.7 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EHU00341.1 - 4.5e-10 39.8 0.0 0.00042 20.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EHU00341.1 - 0.00061 19.3 3.2 0.079 12.4 0.5 3.7 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EHU00341.1 - 0.00075 19.2 0.0 0.0033 17.1 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EHU00341.1 - 0.002 18.1 0.0 0.033 14.1 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase MukB PF04310.12 EHU00341.1 - 0.0031 17.3 0.0 0.013 15.3 0.0 2.0 2 0 0 2 2 2 1 MukB N-terminal AAA_22 PF13401.6 EHU00341.1 - 0.0083 16.4 1.4 0.36 11.1 0.1 3.3 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EHU00341.1 - 0.0099 16.3 0.0 0.29 11.5 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_23 PF13476.6 EHU00341.1 - 0.013 16.0 0.0 0.029 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EHU00341.1 - 0.019 14.7 2.0 0.52 10.0 0.5 3.2 3 1 0 3 3 3 0 AAA domain AFG1_ATPase PF03969.16 EHU00341.1 - 0.036 13.0 0.5 0.45 9.4 0.0 2.3 3 0 0 3 3 3 0 AFG1-like ATPase ABC_ATPase PF09818.9 EHU00341.1 - 0.05 12.4 0.6 17 4.0 0.0 3.6 4 0 0 4 4 4 0 Predicted ATPase of the ABC class MMR_HSR1 PF01926.23 EHU00341.1 - 0.058 13.5 0.0 0.71 10.0 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_15 PF13175.6 EHU00341.1 - 0.19 11.4 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Peripla_BP_4 PF13407.6 EHU00342.1 - 1.4e-61 208.4 20.8 1.6e-61 208.1 20.8 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 EHU00342.1 - 2.1e-13 50.4 3.4 2.5e-13 50.1 3.4 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 EHU00342.1 - 4.2e-07 30.4 0.0 1.2e-06 29.0 0.0 1.7 1 1 1 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_6 PF13458.6 EHU00342.1 - 1.4e-06 28.3 9.7 2.2e-05 24.3 5.5 2.1 1 1 1 2 2 2 2 Periplasmic binding protein Mub_B2 PF17966.1 EHU00342.1 - 0.069 13.9 0.2 0.19 12.5 0.2 1.7 1 0 0 1 1 1 0 Mub B2-like domain Vault_2 PF17794.1 EHU00342.1 - 0.62 10.5 2.9 40 4.7 0.1 3.2 3 0 0 3 3 3 0 Major Vault Protein repeat domain Arm-DNA-bind_3 PF13356.6 EHU00343.1 - 2.5e-21 75.8 0.2 6e-21 74.6 0.2 1.7 1 0 0 1 1 1 1 Arm DNA-binding domain Phage_integrase PF00589.22 EHU00343.1 - 7.4e-20 71.4 0.6 2.7e-19 69.6 0.1 1.9 2 0 0 2 2 2 1 Phage integrase family DUF3435 PF11917.8 EHU00343.1 - 0.0054 15.7 0.1 0.011 14.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) MCPsignal PF00015.21 EHU00344.1 - 4.8e-43 146.9 13.7 4.8e-43 146.9 13.7 1.8 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Mur_ligase_C PF02875.21 EHU00344.1 - 0.058 13.7 0.1 0.14 12.4 0.1 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain HTH_20 PF12840.7 EHU00345.1 - 2.5e-08 33.9 0.1 1.3e-07 31.5 0.1 1.9 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 EHU00345.1 - 0.00033 20.5 0.0 0.0073 16.2 0.1 2.2 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 EHU00345.1 - 0.04 13.8 0.0 0.06 13.2 0.0 1.4 1 1 0 1 1 1 0 MarR family HTH_24 PF13412.6 EHU00345.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Oxidored_FMN PF00724.20 EHU00346.1 - 4.4e-85 285.9 0.0 5.2e-85 285.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 EHU00346.1 - 0.0044 16.5 0.0 0.23 10.9 0.0 2.3 2 0 0 2 2 2 2 Xylose isomerase-like TIM barrel Acetyltransf_1 PF00583.25 EHU00347.1 - 3.4e-08 33.7 0.0 4.1e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EHU00347.1 - 6.9e-07 29.6 0.0 1e-06 29.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EHU00347.1 - 3.6e-05 23.7 0.0 4.9e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyco_transf_20 PF00982.21 EHU00348.1 - 9.8e-97 324.6 0.0 1.2e-96 324.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 GSHPx PF00255.19 EHU00349.1 - 1.2e-41 140.7 0.0 1.4e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 EHU00349.1 - 3.2e-05 23.8 0.0 4.3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EHU00349.1 - 0.023 14.4 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Redoxin YmgB PF10798.8 EHU00350.1 - 0.00039 20.2 0.1 0.00049 19.9 0.1 1.2 1 0 0 1 1 1 1 Biofilm development protein YmgB/AriR FEZ PF07763.13 EHU00351.1 - 0.021 14.6 1.5 0.022 14.5 1.5 1.1 1 0 0 1 1 1 0 FEZ-like protein Sulfate_transp PF00916.20 EHU00354.1 - 4e-55 187.1 31.3 6.4e-29 100.9 14.4 2.3 1 1 0 2 2 2 2 Sulfate permease family STAS PF01740.21 EHU00354.1 - 2.7e-12 46.4 0.1 4.6e-12 45.6 0.1 1.3 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EHU00354.1 - 0.00024 21.5 34.5 0.0012 19.2 6.4 4.1 3 1 1 4 4 4 3 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 EHU00354.1 - 0.011 16.1 0.0 0.029 14.7 0.0 1.7 1 0 0 1 1 1 0 STAS domain BmKX PF09132.10 EHU00354.1 - 0.19 11.7 1.7 0.41 10.7 1.7 1.5 1 0 0 1 1 1 0 BmKX Gaa1 PF04114.14 EHU00354.1 - 2 7.3 12.0 0.029 13.4 4.7 1.7 2 0 0 2 2 2 0 Gaa1-like, GPI transamidase component HAD_2 PF13419.6 EHU00355.1 - 1e-15 58.3 0.0 5.5e-15 55.9 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EHU00355.1 - 4.6e-12 46.7 0.0 1.2e-10 42.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EHU00355.1 - 0.00093 19.2 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EHU00355.1 - 0.011 16.1 0.0 0.015 15.7 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EHU00355.1 - 0.02 15.0 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF2543 PF10820.8 EHU00356.1 - 1.5e-44 150.1 1.3 1.6e-44 149.9 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2543) 2Fe-2S_thioredx PF01257.19 EHU00356.1 - 0.034 14.0 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin Mannitol_dh_C PF08125.13 EHU00356.1 - 0.039 13.4 0.0 0.042 13.3 0.0 1.1 1 0 0 1 1 1 0 Mannitol dehydrogenase C-terminal domain AA_permease_2 PF13520.6 EHU00357.1 - 7.8e-40 137.0 48.3 1.4e-39 136.2 47.4 1.7 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EHU00357.1 - 8.5e-23 80.7 45.6 3.1e-22 78.8 45.5 1.9 1 1 0 1 1 1 1 Amino acid permease DUF1641 PF07849.11 EHU00358.1 - 0.094 12.6 1.1 0.17 11.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1641) LepB_GAP_C PF18227.1 EHU00358.1 - 0.15 12.6 0.0 0.56 10.8 0.0 2.1 1 1 1 2 2 2 0 LepB GAP domain C-terminal subdomain Molydop_binding PF01568.21 EHU00359.1 - 2.3e-23 82.3 0.0 3e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdopterin PF00384.22 EHU00360.1 - 4.2e-78 263.2 0.0 5.2e-78 262.9 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molybdop_Fe4S4 PF04879.16 EHU00360.1 - 1.3e-18 66.7 0.4 4.1e-18 65.1 0.4 2.0 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain Fer4_10 PF13237.6 EHU00360.1 - 3.2e-09 36.7 9.4 0.00075 19.6 4.0 2.9 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 EHU00360.1 - 2.1e-08 33.6 22.3 1.9e-05 24.3 3.0 3.6 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_6 PF12837.7 EHU00360.1 - 9.2e-08 31.8 17.8 0.00075 19.5 3.4 2.8 2 0 0 2 2 2 2 4Fe-4S binding domain NADH-G_4Fe-4S_3 PF10588.9 EHU00360.1 - 3.6e-07 29.6 0.5 3.6e-07 29.6 0.5 2.2 2 0 0 2 2 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer4_21 PF14697.6 EHU00360.1 - 4.2e-06 26.8 9.6 4.2e-06 26.8 9.6 2.5 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 EHU00360.1 - 1.6e-05 25.4 14.7 1.6e-05 25.4 14.7 3.5 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 EHU00360.1 - 1.8e-05 25.1 9.1 1.8e-05 25.1 9.1 2.9 4 0 0 4 4 3 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 EHU00360.1 - 4e-05 23.7 13.7 4e-05 23.7 13.7 3.3 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 EHU00360.1 - 0.00041 21.2 13.4 0.27 12.2 8.5 3.2 2 1 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 EHU00360.1 - 0.0022 18.0 2.4 0.0022 18.0 2.4 3.4 4 0 0 4 4 2 2 4Fe-4S binding domain Fer4_18 PF13746.6 EHU00360.1 - 0.012 15.8 11.9 0.091 13.0 0.9 2.8 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 EHU00360.1 - 0.025 15.3 9.5 0.026 15.2 0.7 2.7 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_17 PF13534.6 EHU00360.1 - 1.2 9.7 23.8 1.1 9.9 15.1 3.6 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 EHU00360.1 - 1.2 9.7 14.9 1.6 9.4 2.0 3.0 3 0 0 3 3 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer2_4 PF13510.6 EHU00361.1 - 7.3e-09 35.6 0.0 8.3e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DDE_3 PF13358.6 EHU00362.1 - 1.1e-22 80.3 0.0 1.9e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 EHU00362.1 - 1.1e-10 41.0 1.0 3.6e-09 36.2 0.1 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 EHU00362.1 - 4.1e-09 36.9 1.1 2.8e-08 34.3 0.3 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 EHU00362.1 - 4e-07 30.0 1.2 1.1e-06 28.6 0.3 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHU00362.1 - 1.4e-05 25.1 0.3 0.0002 21.4 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_33 PF13592.6 EHU00362.1 - 6e-05 22.6 5.4 8.3e-05 22.1 0.5 3.0 3 0 0 3 3 3 1 Winged helix-turn helix LZ_Tnp_IS481 PF13011.6 EHU00362.1 - 0.029 14.9 0.2 0.061 13.8 0.2 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 HTH_38 PF13936.6 EHU00362.1 - 0.052 13.3 0.6 0.16 11.8 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain ADH_N PF08240.12 EHU00363.1 - 3.9e-27 94.3 0.6 9.4e-27 93.1 0.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EHU00363.1 - 1.8e-10 40.9 3.2 6.2e-10 39.2 3.2 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EHU00363.1 - 0.00021 20.9 0.3 0.0035 16.9 0.1 2.1 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 EHU00363.1 - 0.00087 18.6 3.4 0.00098 18.5 2.6 1.5 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_N_assoc PF13823.6 EHU00363.1 - 0.066 13.2 0.2 0.12 12.3 0.2 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated TrkA_N PF02254.18 EHU00363.1 - 0.084 13.1 0.4 0.15 12.3 0.4 1.4 1 0 0 1 1 1 0 TrkA-N domain HTH_Tnp_1 PF01527.20 EHU00365.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU00365.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU00365.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU00365.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHU00366.1 - 7.4e-39 131.7 0.0 8.3e-39 131.6 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHU00367.1 - 2.7e-97 325.7 4.0 1.2e-96 323.5 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU00367.1 - 3.3e-16 59.2 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU00367.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU00367.1 - 8.7e-11 42.4 9.0 1.9e-10 41.4 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Phage_HK97_TLTM PF06120.11 EHU00367.1 - 0.011 15.0 0.8 0.021 14.0 0.8 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHU00367.1 - 0.02 15.2 4.2 0.084 13.2 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain UME PF08064.13 EHU00367.1 - 0.032 14.1 0.3 20 5.1 0.0 3.1 2 1 1 3 3 3 0 UME (NUC010) domain Exonuc_VII_L PF02601.15 EHU00367.1 - 0.039 13.5 2.7 0.04 13.5 1.0 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Troponin PF00992.20 EHU00367.1 - 0.044 14.1 2.8 0.078 13.3 2.8 1.3 1 0 0 1 1 1 0 Troponin FUSC PF04632.12 EHU00367.1 - 0.048 12.2 7.4 0.077 11.5 7.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tho2 PF11262.8 EHU00367.1 - 0.049 12.8 0.6 0.081 12.1 0.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FAM184 PF15665.5 EHU00367.1 - 0.052 13.3 8.0 0.082 12.7 8.0 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B HalX PF08663.10 EHU00367.1 - 0.13 12.6 2.4 0.34 11.3 2.4 1.7 1 0 0 1 1 1 0 HalX domain LXG PF04740.12 EHU00367.1 - 0.14 11.8 2.8 0.35 10.5 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHU00367.1 - 0.19 11.5 11.1 0.31 10.8 11.1 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DHR10 PF18595.1 EHU00367.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Zn-ribbon_8 PF09723.10 EHU00367.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF1192 PF06698.11 EHU00367.1 - 0.54 10.4 5.3 3.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHU00367.1 - 0.82 8.9 3.0 1.2 8.3 3.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHU00367.1 - 2 8.0 8.1 4.3 6.8 8.1 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHU00367.1 - 4.2 7.7 8.6 8.7 6.7 8.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CREPT PF16566.5 EHU00367.1 - 5.9 7.1 8.7 2.7 8.1 5.6 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour SlyX PF04102.12 EHU00367.1 - 9.7 6.9 9.0 18 6.1 2.3 3.0 1 1 1 2 2 2 0 SlyX EAL PF00563.20 EHU00368.1 - 2.9e-63 213.6 0.0 5.6e-63 212.6 0.0 1.4 1 0 0 1 1 1 1 EAL domain PAS_4 PF08448.10 EHU00368.1 - 0.00018 21.7 0.0 0.0022 18.2 0.0 2.5 1 1 0 1 1 1 1 PAS fold PAS PF00989.25 EHU00368.1 - 0.028 14.4 0.0 0.091 12.8 0.0 1.9 1 1 0 1 1 1 0 PAS fold DDE_Tnp_1 PF01609.21 EHU00369.1 - 4.6e-20 72.2 0.0 1.1e-19 70.9 0.0 1.5 1 1 0 1 1 1 1 Transposase DDE domain MCPsignal PF00015.21 EHU00370.1 - 1.4e-47 161.7 35.4 3.4e-47 160.4 17.8 3.8 2 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.7 EHU00370.1 - 0.0011 18.6 0.5 0.0011 18.6 0.5 3.8 4 1 1 5 5 5 1 Four helix bundle sensory module for signal transduction COG2 PF06148.11 EHU00370.1 - 0.015 15.4 1.3 0.015 15.4 1.3 3.5 4 1 0 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 OAD_gamma PF04277.13 EHU00370.1 - 0.033 14.8 0.1 0.033 14.8 0.1 3.2 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain HAMP PF00672.25 EHU00370.1 - 0.21 12.0 6.0 0.32 11.4 0.6 3.9 4 0 0 4 4 4 0 HAMP domain Fez1 PF06818.15 EHU00370.1 - 0.27 11.7 5.9 0.11 13.0 2.8 2.0 2 0 0 2 2 2 0 Fez1 LapA_dom PF06305.11 EHU00370.1 - 0.34 10.7 7.1 0.099 12.5 2.0 2.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF4200 PF13863.6 EHU00370.1 - 0.47 10.9 4.2 0.32 11.4 1.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) APG6_N PF17675.1 EHU00370.1 - 2 9.0 7.6 1.7 9.2 3.1 2.9 3 0 0 3 3 3 0 Apg6 coiled-coil region FIT1_2 PF17357.2 EHU00370.1 - 7.8 6.7 11.5 3.5 7.8 7.1 2.5 2 0 0 2 2 2 0 Facilitor Of iron transport 1 and 2 FMN_bind_2 PF04299.12 EHU00371.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative FMN-binding domain PTS_EIIA_1 PF00358.20 EHU00372.1 - 1e-43 148.1 0.0 1.7e-43 147.4 0.0 1.4 1 0 0 1 1 1 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 PTS_EIIC PF02378.18 EHU00372.1 - 1.9e-34 119.2 31.1 3.2e-34 118.4 31.1 1.4 1 0 0 1 1 1 1 Phosphotransferase system, EIIC PTS_EIIB PF00367.20 EHU00372.1 - 3e-13 49.0 0.0 6.1e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 phosphotransferase system, EIIB Adeno_E3_CR2 PF02439.15 EHU00372.1 - 1.8 8.4 3.8 5 7.0 3.8 1.8 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Glyco_hydro_1 PF00232.18 EHU00373.1 - 1.6e-130 435.6 3.5 1.5e-129 432.3 3.5 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.18 EHU00373.1 - 0.00012 21.6 0.0 0.00029 20.4 0.0 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Abhydrolase_3 PF07859.13 EHU00374.1 - 1.1e-56 192.0 0.0 1.8e-56 191.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EHU00374.1 - 1.8e-08 33.7 0.1 3.9e-08 32.6 0.1 1.4 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.18 EHU00374.1 - 0.00031 20.4 0.0 0.0043 16.6 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EHU00374.1 - 0.00049 19.6 0.2 0.014 14.9 0.1 2.4 2 1 0 2 2 2 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 EHU00374.1 - 0.01 14.7 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase Esterase_phd PF10503.9 EHU00374.1 - 0.045 13.2 0.0 0.093 12.2 0.0 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase ASCH PF04266.14 EHU00375.1 - 4.3e-05 24.1 0.0 7.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 ASCH domain DUF4440 PF14534.6 EHU00375.1 - 0.0011 19.4 0.1 0.0022 18.4 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Aldedh PF00171.22 EHU00377.1 - 5.1e-163 542.9 0.1 5.8e-163 542.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Methyltransf_25 PF13649.6 EHU00378.1 - 2.9e-06 27.9 0.0 5.2e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EHU00378.1 - 4.5e-06 27.3 0.0 6.6e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 EHU00378.1 - 1.8e-05 23.9 0.0 2.1e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.14 EHU00378.1 - 8.6e-05 22.1 0.0 0.00011 21.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 EHU00378.1 - 0.00026 21.6 0.0 0.00044 20.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EHU00378.1 - 0.0014 18.4 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.17 EHU00378.1 - 0.028 14.0 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_PK PF05891.12 EHU00378.1 - 0.056 13.0 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_32 PF13679.6 EHU00378.1 - 0.11 12.5 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain GATase PF00117.28 EHU00379.1 - 1.6e-17 63.9 0.0 2.1e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EHU00379.1 - 1.3e-08 34.8 0.0 2.5e-08 34.0 0.0 1.4 1 1 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.14 EHU00379.1 - 0.096 12.3 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain EamA PF00892.20 EHU00380.1 - 9.5e-38 129.5 41.9 1.6e-19 70.5 16.2 2.0 2 0 0 2 2 2 2 EamA-like transporter family Mg_trans_NIPA PF05653.14 EHU00380.1 - 1e-05 24.8 6.9 0.022 13.9 0.5 2.5 2 0 0 2 2 2 2 Magnesium transporter NIPA CRT-like PF08627.10 EHU00380.1 - 1.8e-05 23.8 2.3 1.8e-05 23.8 2.3 2.3 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like SLC35F PF06027.12 EHU00380.1 - 0.00023 20.8 15.7 0.00072 19.2 15.5 1.9 1 1 0 1 1 1 1 Solute carrier family 35 Multi_Drug_Res PF00893.19 EHU00380.1 - 0.27 11.9 14.3 0.11 13.2 3.5 3.1 2 1 0 2 2 2 0 Small Multidrug Resistance protein Nuc_sug_transp PF04142.15 EHU00380.1 - 0.88 8.7 11.1 0.17 11.0 0.7 2.2 2 0 0 2 2 2 0 Nucleotide-sugar transporter CoA_transf_3 PF02515.17 EHU00381.1 - 1e-47 163.0 0.8 2.9e-45 155.0 0.0 2.7 2 1 0 2 2 2 2 CoA-transferase family III Rnf-Nqr PF02508.14 EHU00381.1 - 0.054 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Rnf-Nqr subunit, membrane protein Nitrate_red_del PF02613.15 EHU00382.1 - 4.5e-11 42.9 0.4 4.5e-11 42.9 0.4 1.6 2 0 0 2 2 2 1 Nitrate reductase delta subunit PHP PF02811.19 EHU00384.1 - 3.3e-08 34.0 0.0 4.1e-08 33.7 0.0 1.3 1 1 0 1 1 1 1 PHP domain 2-Hacid_dh_C PF02826.19 EHU00385.1 - 3.2e-46 156.9 0.0 4.1e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EHU00385.1 - 2.5e-08 34.3 0.0 3.8e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 EHU00385.1 - 0.00028 20.9 0.0 0.00044 20.3 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 EHU00385.1 - 0.00043 20.2 0.0 0.00075 19.4 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EHU00385.1 - 0.014 16.0 0.0 0.026 15.1 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 EHU00385.1 - 0.025 14.8 0.2 0.32 11.2 0.2 2.2 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EHU00385.1 - 0.025 14.6 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 EHU00385.1 - 0.052 13.2 0.1 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trehalase PF01204.18 EHU00386.1 - 5.4e-164 546.8 6.2 7e-164 546.4 6.2 1.1 1 0 0 1 1 1 1 Trehalase Bac_rhamnosid6H PF17389.2 EHU00386.1 - 0.00024 20.5 0.4 0.00045 19.6 0.4 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Glyco_hydro_63 PF03200.16 EHU00386.1 - 0.016 14.0 1.2 0.054 12.2 0.1 2.2 3 0 0 3 3 3 0 Glycosyl hydrolase family 63 C-terminal domain DDE_Tnp_1_5 PF13737.6 EHU00387.1 - 1.2e-44 151.2 0.0 3.1e-44 149.9 0.0 1.7 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 EHU00387.1 - 1.9e-24 86.5 1.0 2.3e-24 86.2 1.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain YcgR PF07317.12 EHU00388.1 - 2.1e-25 88.6 0.0 3.5e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 Flagellar regulator YcgR PilZ PF07238.14 EHU00388.1 - 3.6e-08 33.6 0.0 7.4e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 PilZ domain MS_channel PF00924.18 EHU00389.1 - 7.4e-50 169.4 4.3 1.2e-49 168.7 4.3 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel FGGY_N PF00370.21 EHU00390.1 - 3.5e-58 197.1 0.0 4.6e-58 196.7 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EHU00390.1 - 3.9e-38 131.2 2.1 6.6e-38 130.4 2.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Transketolase_C PF02780.20 EHU00391.1 - 2.2e-27 95.4 0.2 3.2e-27 94.9 0.2 1.3 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 EHU00391.1 - 2.7e-17 63.0 0.0 4.5e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain PFOR_II PF17147.4 EHU00391.1 - 9e-09 35.6 0.0 1.6e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II DHDPS PF00701.22 EHU00391.1 - 0.0049 15.6 0.0 0.0089 14.8 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Filo_glycop PF01611.16 EHU00391.1 - 0.045 12.7 0.0 0.065 12.2 0.0 1.1 1 0 0 1 1 1 0 Filovirus glycoprotein Alba PF01918.21 EHU00391.1 - 0.16 11.8 0.1 0.33 10.8 0.1 1.5 1 0 0 1 1 1 0 Alba DUF3343 PF11823.8 EHU00391.1 - 0.18 11.3 0.5 0.46 10.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3343) Transketolase_N PF00456.21 EHU00392.1 - 1.1e-39 136.3 0.1 1.9e-39 135.5 0.1 1.3 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.6 EHU00392.1 - 2.3e-11 43.4 0.0 2.2e-06 27.1 0.0 2.7 2 1 1 3 3 3 2 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 EHU00392.1 - 5.7e-07 29.4 0.1 1.3e-06 28.2 0.1 1.7 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 EHU00392.1 - 8e-07 28.3 0.0 1.1e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Sugar-bind PF04198.13 EHU00393.1 - 7.6e-60 202.2 0.0 9.2e-60 201.9 0.0 1.0 1 0 0 1 1 1 1 Putative sugar-binding domain MarR_2 PF12802.7 EHU00393.1 - 8.1e-05 22.4 0.2 0.00025 20.9 0.0 1.9 2 0 0 2 2 2 1 MarR family HTH_23 PF13384.6 EHU00393.1 - 0.00032 20.4 0.6 0.0016 18.2 0.1 2.3 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4 PF04545.16 EHU00393.1 - 0.00085 18.8 0.1 0.0023 17.4 0.1 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 KORA PF16509.5 EHU00393.1 - 0.0038 17.5 0.6 0.12 12.7 0.1 2.5 2 0 0 2 2 2 1 TrfB plasmid transcriptional repressor HTH_37 PF13744.6 EHU00393.1 - 0.0076 16.2 0.2 0.021 14.8 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.22 EHU00393.1 - 0.0094 15.9 0.0 0.028 14.4 0.0 1.7 1 0 0 1 1 1 1 MarR family PAX PF00292.18 EHU00393.1 - 0.01 15.7 0.1 0.035 14.0 0.0 1.9 2 0 0 2 2 2 0 'Paired box' domain HTH_Crp_2 PF13545.6 EHU00393.1 - 0.012 15.5 0.1 0.036 14.0 0.1 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_38 PF13936.6 EHU00393.1 - 0.013 15.2 0.1 0.029 14.1 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 EHU00393.1 - 0.018 14.7 0.1 0.042 13.5 0.1 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_40 PF14493.6 EHU00393.1 - 0.034 14.6 0.1 0.074 13.5 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU00393.1 - 0.061 13.4 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn helix KorB PF08535.10 EHU00393.1 - 0.074 13.1 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 KorB domain SLT PF01464.20 EHU00394.1 - 1.9e-26 92.0 0.0 3.4e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 Transglycosylase SLT domain SLT_2 PF13406.6 EHU00394.1 - 0.017 14.4 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Transglycosylase SLT domain Peptidase_S66C PF17676.1 EHU00395.1 - 2.9e-30 105.4 0.0 4.8e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 LD-carboxypeptidase C-terminal domain Peptidase_S66 PF02016.15 EHU00395.1 - 1.3e-25 89.8 0.0 2.3e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 LD-carboxypeptidase N-terminal domain Lactamase_B PF00753.27 EHU00396.1 - 2.4e-06 27.7 0.4 4.4e-06 26.8 0.3 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Acetyltransf_10 PF13673.7 EHU00397.1 - 1.2e-11 44.7 0.0 1.4e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EHU00397.1 - 4.6e-11 43.0 0.0 5.5e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EHU00397.1 - 3.3e-09 37.1 0.0 4.2e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EHU00397.1 - 0.00011 22.1 0.0 0.00014 21.7 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EHU00397.1 - 0.00017 21.6 0.0 0.00028 21.0 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF883 PF05957.13 EHU00403.1 - 2.2e-11 44.2 1.2 3.6e-11 43.5 1.2 1.4 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF883) CsbD PF05532.12 EHU00403.1 - 9.4e-09 35.0 0.3 1.2e-08 34.7 0.3 1.1 1 0 0 1 1 1 1 CsbD-like Sugar_tr PF00083.24 EHU00404.1 - 7.9e-25 87.6 26.7 9.1e-18 64.3 9.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EHU00404.1 - 9.1e-22 77.5 43.9 6.8e-12 45.0 18.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EHU00404.1 - 0.0026 16.2 17.9 0.026 13.0 9.7 2.4 2 1 0 2 2 2 2 Transmembrane secretion effector DDE_Tnp_IS66 PF03050.14 EHU00405.1 - 2.7e-97 325.7 4.0 1.2e-96 323.5 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU00405.1 - 3.3e-16 59.2 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU00405.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU00405.1 - 8.7e-11 42.4 9.0 1.9e-10 41.4 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Phage_HK97_TLTM PF06120.11 EHU00405.1 - 0.011 15.0 0.8 0.021 14.0 0.8 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHU00405.1 - 0.02 15.2 4.2 0.084 13.2 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain UME PF08064.13 EHU00405.1 - 0.032 14.1 0.3 20 5.1 0.0 3.1 2 1 1 3 3 3 0 UME (NUC010) domain Exonuc_VII_L PF02601.15 EHU00405.1 - 0.039 13.5 2.7 0.04 13.5 1.0 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Troponin PF00992.20 EHU00405.1 - 0.044 14.1 2.8 0.078 13.3 2.8 1.3 1 0 0 1 1 1 0 Troponin FUSC PF04632.12 EHU00405.1 - 0.048 12.2 7.4 0.077 11.5 7.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tho2 PF11262.8 EHU00405.1 - 0.049 12.8 0.6 0.081 12.1 0.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FAM184 PF15665.5 EHU00405.1 - 0.052 13.3 8.0 0.082 12.7 8.0 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B HalX PF08663.10 EHU00405.1 - 0.13 12.6 2.4 0.34 11.3 2.4 1.7 1 0 0 1 1 1 0 HalX domain LXG PF04740.12 EHU00405.1 - 0.14 11.8 2.8 0.35 10.5 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHU00405.1 - 0.19 11.5 11.1 0.31 10.8 11.1 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DHR10 PF18595.1 EHU00405.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Zn-ribbon_8 PF09723.10 EHU00405.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF1192 PF06698.11 EHU00405.1 - 0.54 10.4 5.3 3.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHU00405.1 - 0.82 8.9 3.0 1.2 8.3 3.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHU00405.1 - 2 8.0 8.1 4.3 6.8 8.1 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHU00405.1 - 4.2 7.7 8.6 8.7 6.7 8.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CREPT PF16566.5 EHU00405.1 - 5.9 7.1 8.7 2.7 8.1 5.6 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour SlyX PF04102.12 EHU00405.1 - 9.7 6.9 9.0 18 6.1 2.3 3.0 1 1 1 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHU00406.1 - 7.4e-39 131.7 0.0 8.3e-39 131.6 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHU00407.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU00407.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU00407.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU00407.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix FAD_binding_3 PF01494.19 EHU00409.1 - 3.4e-48 164.7 0.0 4.9e-48 164.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 EHU00409.1 - 2.6e-09 36.7 0.3 4.2e-05 22.8 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EHU00409.1 - 8.3e-08 32.4 0.2 2e-07 31.1 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EHU00409.1 - 9.1e-08 32.1 0.0 5.7e-06 26.1 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EHU00409.1 - 6.6e-07 28.8 0.0 3.2e-05 23.3 0.0 2.4 2 1 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 EHU00409.1 - 1.8e-06 26.9 0.0 2.9e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 EHU00409.1 - 3.4e-06 26.3 1.2 0.00013 21.1 0.7 2.8 2 1 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.14 EHU00409.1 - 8.6e-06 24.9 0.1 0.023 13.6 0.0 2.7 2 1 0 2 2 2 2 Tryptophan halogenase Pyr_redox_3 PF13738.6 EHU00409.1 - 2.9e-05 23.5 0.0 4.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EHU00409.1 - 8e-05 22.2 0.7 0.00073 19.0 0.7 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EHU00409.1 - 9.8e-05 21.7 0.0 0.00028 20.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EHU00409.1 - 0.00082 19.9 0.0 0.0018 18.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EHU00409.1 - 0.0015 17.7 0.0 0.0041 16.2 0.0 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 EHU00409.1 - 0.027 14.4 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EHU00409.1 - 0.061 13.8 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding SE PF08491.10 EHU00409.1 - 0.083 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase K_oxygenase PF13434.6 EHU00409.1 - 0.12 11.5 0.1 0.77 8.8 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 EHU00409.1 - 0.21 10.8 0.5 0.49 9.6 0.3 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase CdiI_2 PF18593.1 EHU00412.1 - 2.4e-05 24.9 0.0 3e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 CdiI immunity protein Iso_dh PF00180.20 EHU00413.1 - 2.6e-07 30.1 0.0 2.8e-07 30.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Baseplate_J PF04865.14 EHU00416.1 - 1.7e-07 30.6 1.0 5e-07 29.1 1.0 1.6 1 1 0 1 1 1 1 Baseplate J-like protein DDE_3 PF13358.6 EHU00417.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHU00417.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHU00417.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHU00417.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHU00417.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHU00417.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHU00417.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHU00417.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 FTP PF07504.13 EHU00421.1 - 0.016 15.0 0.1 0.028 14.3 0.1 1.4 1 0 0 1 1 1 0 Fungalysin/Thermolysin Propeptide Motif SLT PF01464.20 EHU00423.1 - 1.3e-23 82.9 1.6 1.4e-23 82.8 0.1 1.8 2 0 0 2 2 2 1 Transglycosylase SLT domain Transglycosylas PF06737.14 EHU00423.1 - 0.0054 17.3 1.3 0.022 15.4 0.0 2.7 3 0 0 3 3 3 1 Transglycosylase-like domain Phage_lysozyme2 PF18013.1 EHU00423.1 - 0.028 14.4 0.1 0.082 12.9 0.0 1.9 2 0 0 2 2 2 0 Phage tail lysozyme SLT_2 PF13406.6 EHU00423.1 - 0.03 13.6 0.0 0.061 12.6 0.0 1.5 1 0 0 1 1 1 0 Transglycosylase SLT domain WXG100 PF06013.12 EHU00423.1 - 7.4 6.9 12.9 1.6 9.0 1.0 4.1 5 0 0 5 5 5 0 Proteins of 100 residues with WXG CsoS2_M PF12288.8 EHU00425.1 - 0.039 13.4 0.0 0.052 12.9 0.0 1.1 1 0 0 1 1 1 0 Carboxysome shell peptide mid-region TIG_2 PF18020.1 EHU00430.1 - 0.09 13.4 0.0 0.23 12.1 0.0 1.7 1 0 0 1 1 1 0 TIG domain found in plexin DUF2184 PF09950.9 EHU00431.1 - 3e-06 26.8 0.1 4.6e-06 26.2 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2184) DUF2213 PF09979.9 EHU00433.1 - 0.00023 21.2 0.0 0.00048 20.2 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2213) BUD22 PF09073.10 EHU00433.1 - 0.0023 17.3 18.1 0.0031 16.9 18.1 1.1 1 0 0 1 1 1 1 BUD22 Tim54 PF11711.8 EHU00433.1 - 0.028 13.2 8.9 0.038 12.8 8.9 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Spore_coat_CotO PF14153.6 EHU00433.1 - 0.055 13.4 13.9 0.081 12.9 13.9 1.3 1 0 0 1 1 1 0 Spore coat protein CotO CAF-1_p150 PF11600.8 EHU00433.1 - 0.056 13.1 26.6 0.11 12.2 26.6 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RR_TM4-6 PF06459.12 EHU00433.1 - 0.072 12.9 14.8 0.12 12.2 14.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Borrelia_P83 PF05262.11 EHU00433.1 - 0.12 10.8 17.8 0.16 10.4 17.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DDHD PF02862.17 EHU00433.1 - 0.15 12.2 4.0 0.23 11.6 4.0 1.3 1 0 0 1 1 1 0 DDHD domain DDRGK PF09756.9 EHU00433.1 - 0.19 11.3 19.8 0.34 10.5 19.8 1.4 1 0 0 1 1 1 0 DDRGK domain CCDC53 PF10152.9 EHU00433.1 - 0.22 11.9 10.0 0.4 11.1 10.0 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Zip PF02535.22 EHU00433.1 - 0.28 10.4 5.6 0.35 10.0 5.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SAPS PF04499.15 EHU00433.1 - 0.4 9.4 8.7 0.53 9.0 8.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DHHW PF14286.6 EHU00433.1 - 0.4 10.0 4.3 0.56 9.5 4.3 1.2 1 0 0 1 1 1 0 DHHW protein RNA_pol_Rpc4 PF05132.14 EHU00433.1 - 0.4 11.1 10.8 0.93 9.9 10.8 1.7 1 0 0 1 1 1 0 RNA polymerase III RPC4 Silic_transp PF03842.13 EHU00433.1 - 0.43 8.8 2.4 14 3.8 2.8 2.2 2 0 0 2 2 2 0 Silicon transporter FGF-BP1 PF06473.12 EHU00433.1 - 0.51 10.1 12.8 0.79 9.5 12.8 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) DUF4746 PF15928.5 EHU00433.1 - 0.56 9.6 14.3 0.95 8.8 14.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF2514 PF10721.9 EHU00433.1 - 0.67 10.0 17.8 1.2 9.1 17.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) NARP1 PF12569.8 EHU00433.1 - 0.7 8.7 19.7 0.97 8.3 19.7 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RPN2_C PF18004.1 EHU00433.1 - 0.73 9.7 19.0 1.3 8.9 19.0 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF1943 PF09172.11 EHU00433.1 - 0.9 8.7 3.3 1.4 8.1 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) SLC12 PF03522.15 EHU00433.1 - 0.97 8.4 9.2 1.3 8.0 9.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CDC45 PF02724.14 EHU00433.1 - 1 7.6 16.1 1.3 7.3 16.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4407 PF14362.6 EHU00433.1 - 1.1 8.6 10.7 1.4 8.2 10.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Vfa1 PF08432.10 EHU00433.1 - 1.1 9.6 18.7 1.8 8.8 18.7 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Sec62 PF03839.16 EHU00433.1 - 1.3 8.5 11.4 2.1 7.8 11.4 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Coilin_N PF15862.5 EHU00433.1 - 1.4 8.7 11.2 2.9 7.7 11.2 1.6 1 0 0 1 1 1 0 Coilin N-terminus TP53IP5 PF15331.6 EHU00433.1 - 1.5 8.9 9.7 2.3 8.3 9.7 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DUF5523 PF17661.1 EHU00433.1 - 1.7 8.3 17.8 15 5.1 17.9 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5523) PPP4R2 PF09184.11 EHU00433.1 - 2.3 7.7 17.3 12 5.4 17.6 2.0 2 0 0 2 2 2 0 PPP4R2 DUF2151 PF10221.9 EHU00433.1 - 2.6 6.6 11.7 3.4 6.1 11.7 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator ALMT PF11744.8 EHU00433.1 - 2.9 6.6 6.8 4.3 6.0 6.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter NPR3 PF03666.13 EHU00433.1 - 3.2 6.5 12.9 4.1 6.1 12.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 LAP1C PF05609.12 EHU00433.1 - 3.3 6.7 15.3 4.4 6.3 15.3 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) FAM60A PF15396.6 EHU00433.1 - 3.5 7.6 9.8 5.1 7.0 9.8 1.3 1 0 0 1 1 1 0 Protein Family FAM60A PA26 PF04636.13 EHU00433.1 - 3.7 6.4 6.3 4.6 6.1 6.3 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Presenilin PF01080.17 EHU00433.1 - 4.2 6.0 13.3 5.6 5.6 13.3 1.1 1 0 0 1 1 1 0 Presenilin RRN3 PF05327.11 EHU00433.1 - 4.3 5.7 10.4 6.2 5.2 10.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PPL5 PF18168.1 EHU00433.1 - 5.4 6.2 12.6 3.8 6.7 11.1 1.5 2 0 0 2 2 1 0 Prim-pol family 5 DUF913 PF06025.12 EHU00433.1 - 6.4 5.7 8.9 9.9 5.0 8.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) MMR1 PF08505.10 EHU00433.1 - 6.7 6.9 12.3 10 6.3 12.3 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF1073 PF06381.11 EHU00435.1 - 1e-14 54.2 0.0 1.4e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1073) DUF4089 PF13318.6 EHU00436.1 - 0.052 14.0 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4089) Terminase_6 PF03237.15 EHU00436.1 - 0.076 12.7 0.4 0.33 10.6 0.0 2.3 2 1 0 2 2 2 0 Terminase-like family Terminase_2 PF03592.16 EHU00437.1 - 3.1e-10 40.6 0.0 1.9e-09 38.1 0.0 1.9 1 1 1 2 2 2 1 Terminase small subunit L27_1 PF09058.10 EHU00437.1 - 0.087 12.8 0.7 0.17 11.9 0.7 1.5 1 0 0 1 1 1 0 L27_1 ParBc PF02195.18 EHU00440.1 - 4.4e-06 26.9 0.0 6.6e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 ParB-like nuclease domain Methyltransf_23 PF13489.6 EHU00441.1 - 6.8e-08 32.5 0.1 8.8e-08 32.2 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Glyco_transf_9 PF01075.17 EHU00442.1 - 9.5e-05 21.8 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) MGTL PF17059.5 EHU00442.1 - 1.4 8.8 3.9 0.68 9.8 0.2 2.3 2 0 0 2 2 2 0 MgtA leader peptide DUF2514 PF10721.9 EHU00444.1 - 2.6e-31 108.8 16.7 3e-31 108.6 16.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2514) BRE1 PF08647.11 EHU00444.1 - 0.0045 17.0 2.5 0.006 16.6 2.5 1.2 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase ATG16 PF08614.11 EHU00444.1 - 0.017 15.4 8.1 0.021 15.1 8.1 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 EHU00444.1 - 0.43 9.9 11.0 0.55 9.5 11.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FUSC PF04632.12 EHU00444.1 - 1.4 7.4 8.4 1.6 7.2 8.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Glyco_hydro_19 PF00182.19 EHU00445.1 - 9.6e-09 35.5 0.4 1.4e-07 31.7 0.4 2.5 1 1 0 1 1 1 1 Chitinase class I Phage_holin_3_7 PF05449.11 EHU00446.1 - 1.1e-22 79.8 1.7 1.4e-22 79.5 1.7 1.1 1 0 0 1 1 1 1 Putative 3TM holin, Phage_holin_3 DUF2767 PF10965.8 EHU00447.1 - 5.4e-17 61.5 0.1 5.7e-17 61.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2767) Phage_antiter_Q PF06323.11 EHU00448.1 - 8.2e-48 162.9 0.0 1e-47 162.6 0.0 1.0 1 0 0 1 1 1 1 Phage antitermination protein Q Sacchrp_dh_C PF16653.5 EHU00448.1 - 0.067 13.3 0.0 0.075 13.1 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase C-terminal domain DUF1364 PF07102.12 EHU00449.1 - 1e-30 105.4 0.1 1.1e-30 105.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1364) Dam PF05869.11 EHU00450.1 - 5.5e-56 188.8 0.0 6.5e-56 188.6 0.0 1.0 1 0 0 1 1 1 1 DNA N-6-adenine-methyltransferase (Dam) DUF1367 PF07105.11 EHU00451.1 - 5.1e-81 271.0 0.6 5.7e-81 270.9 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1367) TnpB_IS66 PF05717.13 EHU00452.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHU00453.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU00453.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU00453.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU00453.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix EOS1 PF12326.8 EHU00454.1 - 0.0044 17.0 0.1 0.0081 16.1 0.1 1.5 1 0 0 1 1 1 1 N-glycosylation protein Glycos_transf_2 PF00535.26 EHU00454.1 - 0.024 14.4 0.0 0.066 13.0 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glycos_transf_2 PF00535.26 EHU00455.1 - 2.3e-20 73.1 0.0 2.4e-19 69.8 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EHU00455.1 - 6.9e-15 55.6 0.1 2e-14 54.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EHU00455.1 - 1.1e-09 38.2 0.0 4.2e-09 36.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_5 PF13712.6 EHU00455.1 - 3.3e-06 27.0 0.0 7.9e-06 25.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family Glyco_transf_21 PF13506.6 EHU00455.1 - 0.0056 16.2 0.2 0.03 13.8 0.1 2.3 3 1 0 3 3 3 1 Glycosyl transferase family 21 Glyco_trans_1_2 PF13524.6 EHU00455.1 - 0.025 14.9 0.0 0.1 13.0 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EHU00455.1 - 0.17 12.3 0.0 0.44 11.0 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_tranf_2_4 PF13704.6 EHU00455.1 - 0.32 11.5 2.1 0.97 10.0 0.8 2.6 2 1 0 2 2 2 0 Glycosyl transferase family 2 Flagellin_N PF00669.20 EHU00456.1 - 3.5e-41 140.6 18.5 3.5e-41 140.6 18.5 2.8 2 1 1 3 3 3 1 Bacterial flagellin N-terminal helical region Flagellin_C PF00700.21 EHU00456.1 - 1.3e-29 102.3 8.2 1.3e-29 102.3 8.2 4.3 3 1 2 5 5 5 2 Bacterial flagellin C-terminal helical region Snapin_Pallidin PF14712.6 EHU00456.1 - 0.015 15.7 4.9 5.2 7.6 0.1 3.5 3 1 0 3 3 3 0 Snapin/Pallidin BLOC1_2 PF10046.9 EHU00456.1 - 0.044 14.1 2.4 0.25 11.7 1.0 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3829 PF12889.7 EHU00456.1 - 0.28 10.6 5.8 3.2 7.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) Muted PF14942.6 EHU00456.1 - 0.3 11.4 3.9 1.5 9.1 0.5 2.3 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein HAUS-augmin3 PF14932.6 EHU00456.1 - 0.65 9.5 4.0 1.2 8.6 0.3 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF1664 PF07889.12 EHU00456.1 - 1.9 8.5 7.8 72 3.4 3.8 3.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) FliD_C PF07195.12 EHU00457.1 - 1.8e-59 201.1 20.6 1.8e-59 201.1 20.6 2.6 2 1 0 2 2 2 1 Flagellar hook-associated protein 2 C-terminus FliD_N PF02465.18 EHU00457.1 - 5.6e-19 68.6 14.0 5.6e-19 68.6 14.0 5.3 3 1 1 4 4 4 1 Flagellar hook-associated protein 2 N-terminus Laminin_II PF06009.12 EHU00457.1 - 0.016 15.3 1.2 0.016 15.3 1.2 3.7 3 1 1 4 4 4 0 Laminin Domain II TolA_bind_tri PF16331.5 EHU00457.1 - 0.026 14.6 0.3 0.11 12.5 0.3 2.1 1 0 0 1 1 1 0 TolA binding protein trimerisation FliS PF02561.14 EHU00458.1 - 1.5e-38 131.6 0.1 1.7e-38 131.4 0.1 1.0 1 0 0 1 1 1 1 Flagellar protein FliS FliT PF05400.13 EHU00459.1 - 4.3e-20 72.3 1.0 5.6e-20 71.9 1.0 1.2 1 0 0 1 1 1 1 Flagellar protein FliT YedD PF13987.6 EHU00460.1 - 9.8e-50 166.8 0.1 1.2e-49 166.5 0.1 1.1 1 0 0 1 1 1 1 YedD-like protein MHB PF16525.5 EHU00461.1 - 0.25 11.6 1.1 6.1 7.2 0.2 2.1 1 1 1 2 2 2 0 Haemophore, haem-binding Anti-adapt_IraP PF10796.9 EHU00462.1 - 4.6e-28 97.6 9.8 5.2e-28 97.4 9.8 1.0 1 0 0 1 1 1 1 Sigma-S stabilisation anti-adaptor protein DUF4054 PF13262.6 EHU00462.1 - 0.071 13.1 0.3 0.087 12.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4054) DinI PF06183.13 EHU00463.1 - 1.5e-18 66.9 0.1 1.9e-18 66.5 0.1 1.1 1 0 0 1 1 1 1 DinI-like family Bacillus_HBL PF05791.11 EHU00464.1 - 0.012 15.5 0.8 0.013 15.4 0.8 1.0 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DEDD_Tnp_IS110 PF01548.17 EHU00466.1 - 5e-19 68.7 0.3 7.9e-19 68.1 0.3 1.3 1 0 0 1 1 1 1 Transposase Transposase_20 PF02371.16 EHU00466.1 - 9.5e-15 54.7 0.3 2.3e-14 53.5 0.3 1.6 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family Stomagen PF16851.5 EHU00466.1 - 0.053 13.5 0.0 0.087 12.8 0.0 1.4 1 0 0 1 1 1 0 Stomagen DUF913 PF06025.12 EHU00466.1 - 0.088 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TetR_C_30 PF17939.1 EHU00466.1 - 0.11 12.7 2.1 0.22 11.8 1.7 1.6 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DDE_Tnp_ISL3 PF01610.17 EHU00470.1 - 1e-56 192.4 0.6 1.4e-56 191.9 0.6 1.2 1 0 0 1 1 1 1 Transposase HTH_Tnp_ISL3 PF13542.6 EHU00470.1 - 2.8e-12 45.8 0.0 9.1e-12 44.2 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 zf-ISL3 PF14690.6 EHU00470.1 - 5.4e-10 39.8 9.5 5.4e-10 39.8 9.5 1.9 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 PhnA_Zn_Ribbon PF08274.12 EHU00470.1 - 0.062 13.3 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 PhnA Zinc-Ribbon FANCI_S1-cap PF14674.6 EHU00470.1 - 0.068 13.3 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 FANCI solenoid 1 cap Caudo_TAP PF02413.17 EHU00471.1 - 3.9e-18 65.9 0.4 4.2e-18 65.8 0.4 1.0 1 0 0 1 1 1 1 Caudovirales tail fibre assembly protein, lambda gpK Baseplate_J PF04865.14 EHU00473.1 - 2.7e-39 134.9 13.0 4.2e-39 134.2 13.0 1.3 1 0 0 1 1 1 1 Baseplate J-like protein DUF2634 PF10934.8 EHU00474.1 - 0.0063 16.6 0.0 0.0074 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2634) GPW_gp25 PF04965.14 EHU00474.1 - 0.15 11.8 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Gene 25-like lysozyme Phage_P2_GpU PF06995.11 EHU00477.1 - 0.011 15.3 0.0 0.03 13.9 0.0 1.7 2 0 0 2 2 2 0 Phage P2 GpU BAR_3 PF16746.5 EHU00478.1 - 0.03 14.0 0.6 0.13 11.9 0.1 2.1 2 0 0 2 2 2 0 BAR domain of APPL family RmuC PF02646.16 EHU00478.1 - 0.06 12.5 0.3 0.14 11.2 0.3 1.6 1 0 0 1 1 1 0 RmuC family Laminin_II PF06009.12 EHU00478.1 - 0.06 13.4 0.4 0.2 11.7 0.4 1.8 1 0 0 1 1 1 0 Laminin Domain II Spc7 PF08317.11 EHU00478.1 - 0.15 10.9 0.1 0.29 10.0 0.1 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein MscS_porin PF12795.7 EHU00478.1 - 0.18 11.3 2.0 0.37 10.3 2.0 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Baculo_PEP_C PF04513.12 EHU00478.1 - 0.73 9.9 2.5 4.8 7.2 0.4 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus P22_AR_N PF10547.9 EHU00480.1 - 4.5e-38 130.1 0.0 5.9e-38 129.7 0.0 1.2 1 0 0 1 1 1 1 P22_AR N-terminal domain Arc PF03869.14 EHU00481.1 - 1.6e-12 47.1 1.2 1.7e-12 46.9 1.2 1.1 1 0 0 1 1 1 1 Arc-like DNA binding domain HicB PF05534.12 EHU00481.1 - 5.4e-05 22.9 0.0 6.8e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 HicB family RHH_1 PF01402.21 EHU00481.1 - 0.0073 16.2 0.6 0.012 15.5 0.6 1.5 1 1 0 1 1 1 1 Ribbon-helix-helix protein, copG family CopG_antitoxin PF12441.8 EHU00481.1 - 0.0075 16.8 0.0 0.0092 16.5 0.0 1.1 1 0 0 1 1 1 1 CopG antitoxin of type II toxin-antitoxin system FliG_M PF14841.6 EHU00481.1 - 0.016 15.4 0.7 0.021 15.0 0.7 1.1 1 0 0 1 1 1 0 FliG middle domain Arc PF03869.14 EHU00482.1 - 2.2e-18 65.8 0.0 5.3e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 Arc-like DNA binding domain SpvD PF05563.12 EHU00482.1 - 0.04 13.5 0.0 0.046 13.3 0.0 1.1 1 0 0 1 1 1 0 Salmonella plasmid virulence protein SpvD HicB PF05534.12 EHU00482.1 - 0.042 13.7 0.0 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 HicB family RHH_5 PF07878.11 EHU00482.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 Phage_tail_S PF05069.13 EHU00483.1 - 9.6e-08 32.0 0.0 2.3e-07 30.7 0.0 1.6 1 1 0 1 1 1 1 Phage virion morphogenesis family HK97-gp10_like PF04883.12 EHU00483.1 - 0.038 15.0 0.0 0.11 13.5 0.0 1.8 1 1 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component DUF1921 PF09081.10 EHU00486.1 - 0.068 13.4 0.1 0.26 11.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1921) Phage_sheath_1N PF17481.2 EHU00487.1 - 0.00019 21.8 6.8 0.00062 20.2 5.4 2.5 2 0 0 2 2 2 1 Phage tail sheath protein beta-sandwich domain Phage_sheath_1C PF17482.2 EHU00487.1 - 0.0029 17.6 0.0 0.0058 16.6 0.0 1.5 1 0 0 1 1 1 1 Phage tail sheath C-terminal domain TOM13 PF08219.11 EHU00490.1 - 0.097 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Outer membrane protein TOM13 DUF1799 PF08809.11 EHU00491.1 - 0.033 14.4 0.1 0.48 10.7 0.0 2.1 1 1 1 2 2 2 0 Phage related hypothetical protein (DUF1799) KapB PF08810.10 EHU00491.1 - 0.21 11.8 0.0 1 9.5 0.0 2.0 1 1 0 1 1 1 0 Kinase associated protein B P22_CoatProtein PF11651.8 EHU00493.1 - 1.7e-16 59.9 3.0 1.6e-13 50.1 1.5 2.1 2 0 0 2 2 2 2 P22 coat protein - gene protein 5 FliC PF12445.8 EHU00494.1 - 0.015 15.7 0.4 0.074 13.4 0.0 2.1 2 0 0 2 2 2 0 Flagellin protein GbpC PF08363.10 EHU00494.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Glucan-binding protein C Stn1 PF10451.9 EHU00494.1 - 0.22 10.4 0.1 0.35 9.8 0.1 1.2 1 0 0 1 1 1 0 Telomere regulation protein Stn1 DUF4055 PF13264.6 EHU00495.1 - 2.1e-41 141.2 0.1 3.3e-41 140.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4055) Terminase_6C PF17289.2 EHU00496.1 - 3.9e-11 43.3 0.1 6.4e-11 42.6 0.1 1.4 1 0 0 1 1 1 1 Terminase RNaseH-like domain DUF166 PF02593.14 EHU00498.1 - 0.075 12.6 0.0 0.12 11.9 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function SBP_bac_3 PF00497.20 EHU00500.1 - 0.11 11.9 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 Leu_zip PF15294.6 EHU00502.1 - 0.0071 15.9 1.4 0.0086 15.6 1.4 1.1 1 0 0 1 1 1 1 Leucine zipper DUF2478 PF10649.9 EHU00502.1 - 0.032 13.8 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2478) PIG-L PF02585.17 EHU00502.1 - 0.092 13.4 0.1 0.11 13.1 0.1 1.2 1 0 0 1 1 1 0 GlcNAc-PI de-N-acetylase DUF3708 PF12501.8 EHU00502.1 - 0.15 11.8 0.2 0.18 11.6 0.2 1.1 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter PikAIV_N PF18605.1 EHU00502.1 - 0.18 11.4 5.5 0.69 9.5 1.0 3.2 3 0 0 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain bZIP_1 PF00170.21 EHU00502.1 - 0.34 11.0 9.2 1.8 8.7 1.7 2.4 1 1 1 2 2 2 0 bZIP transcription factor DivIC PF04977.15 EHU00502.1 - 0.35 10.7 5.6 0.081 12.7 1.3 2.0 1 1 1 2 2 2 0 Septum formation initiator Glyco_hydro_19 PF00182.19 EHU00503.1 - 2.4e-08 34.2 0.1 2.9e-08 33.9 0.1 1.1 1 0 0 1 1 1 1 Chitinase class I Phage_holin_3_3 PF16083.5 EHU00504.1 - 4.8e-16 58.6 7.2 7.6e-16 58.0 7.2 1.3 1 0 0 1 1 1 1 LydA holin phage, holin superfamily III DUF1440 PF07274.12 EHU00504.1 - 0.00087 19.7 0.2 0.001 19.4 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1440) Phage_holin_3_1 PF05106.12 EHU00504.1 - 0.0022 18.4 1.8 0.0029 18.0 1.8 1.2 1 0 0 1 1 1 1 Phage holin family (Lysis protein S) PHO4 PF01384.20 EHU00504.1 - 0.035 13.2 1.6 0.038 13.0 1.6 1.0 1 0 0 1 1 1 0 Phosphate transporter family DUF3341 PF11821.8 EHU00504.1 - 4.5 6.9 5.7 10 5.7 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3341) Antiterm PF03589.13 EHU00505.1 - 9.7e-44 147.6 1.5 6.5e-22 77.7 0.4 2.6 3 0 0 3 3 3 2 Antitermination protein DnaJ_CXXCXGXG PF00684.19 EHU00505.1 - 0.0034 17.7 17.2 0.0089 16.4 11.1 2.7 2 1 0 2 2 2 2 DnaJ central domain Anti-TRAP PF15777.5 EHU00505.1 - 0.86 9.6 15.6 1.4 9.0 1.6 3.3 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein RusA PF05866.11 EHU00506.1 - 5.5e-17 62.5 0.0 6.5e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Endodeoxyribonuclease RusA DUF1364 PF07102.12 EHU00507.1 - 1.2e-43 146.9 0.2 1.3e-43 146.7 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1364) Mur_ligase PF01225.25 EHU00507.1 - 0.096 13.0 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, catalytic domain DUF968 PF06147.11 EHU00507.1 - 0.1 12.8 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF968) NinB PF05772.12 EHU00510.1 - 1.2e-48 164.3 0.1 1.6e-48 163.8 0.1 1.2 1 0 0 1 1 1 1 NinB protein DUF2840 PF11000.8 EHU00510.1 - 0.047 13.5 0.1 0.064 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2840) DnaB_C PF03796.15 EHU00513.1 - 2.7e-64 217.0 0.0 1.1e-62 211.7 0.0 2.1 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain DnaB PF00772.21 EHU00513.1 - 4.9e-15 55.5 0.0 1e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 DnaB-like helicase N terminal domain ATPase PF06745.13 EHU00513.1 - 1.6e-07 30.9 0.1 2.5e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.6 EHU00513.1 - 1.1e-06 28.4 0.0 2.1e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EHU00513.1 - 0.0018 17.6 0.0 0.0042 16.4 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 EHU00513.1 - 0.0025 18.3 0.0 0.0071 16.8 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) GvpD PF07088.11 EHU00513.1 - 0.0031 16.2 0.0 0.0044 15.7 0.0 1.2 1 0 0 1 1 1 1 GvpD gas vesicle protein AAA_5 PF07728.14 EHU00513.1 - 0.0057 16.7 0.1 0.013 15.5 0.1 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 EHU00513.1 - 0.011 15.7 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain RuvB_N PF05496.12 EHU00513.1 - 0.012 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 EHU00513.1 - 0.015 15.1 0.1 0.03 14.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 EHU00513.1 - 0.019 14.2 0.1 0.039 13.2 0.1 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Zeta_toxin PF06414.12 EHU00513.1 - 0.029 13.6 0.0 0.059 12.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.17 EHU00513.1 - 0.052 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.6 EHU00513.1 - 0.16 12.4 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Phage_rep_O PF04492.13 EHU00514.1 - 7.3e-06 26.5 0.2 1.6e-05 25.4 0.0 1.7 2 0 0 2 2 2 1 Bacteriophage replication protein O Atg14 PF10186.9 EHU00517.1 - 0.0042 16.2 2.0 0.0062 15.7 2.0 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Pentapeptide PF00805.22 EHU00518.1 - 1.7e-63 209.7 25.0 2.9e-15 55.5 1.0 4.9 1 1 0 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 EHU00518.1 - 5.8e-25 87.2 0.0 5.5e-06 26.4 0.0 4.4 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.6 EHU00518.1 - 1.9e-19 69.6 0.0 1.7e-08 34.5 0.0 3.4 1 1 0 2 2 2 2 Pentapeptide repeats (9 copies) AAA_24 PF13479.6 EHU00521.1 - 9.8e-29 100.5 0.0 1.3e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EHU00521.1 - 0.0083 16.4 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EHU00521.1 - 0.05 14.0 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pox_A32 PF04665.12 EHU00521.1 - 0.058 12.8 0.1 0.092 12.2 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein NTPase_1 PF03266.15 EHU00521.1 - 0.074 13.0 0.5 13 5.7 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_18 PF13238.6 EHU00521.1 - 0.11 13.0 0.0 0.23 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EHU00521.1 - 0.13 12.6 0.0 0.63 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain SSB PF00436.25 EHU00522.1 - 7.6e-31 106.3 0.6 1e-30 105.9 0.6 1.2 1 0 0 1 1 1 1 Single-strand binding protein family DUF4792 PF16040.5 EHU00522.1 - 0.031 14.2 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4792) BATS PF06968.13 EHU00523.1 - 0.11 12.7 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Biotin and Thiamin Synthesis associated domain DUF1024 PF06260.12 EHU00525.1 - 0.0049 17.1 0.1 0.0068 16.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1024) HALZ PF02183.18 EHU00525.1 - 0.076 13.3 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper DHR10 PF18595.1 EHU00525.1 - 0.085 12.9 0.2 0.14 12.2 0.2 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Adeno_PV PF03910.13 EHU00525.1 - 0.14 10.9 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Adenovirus minor core protein PV MT-A70 PF05063.14 EHU00530.1 - 1.8e-25 89.8 0.0 2.1e-25 89.6 0.0 1.0 1 0 0 1 1 1 1 MT-A70 Arm-DNA-bind_2 PF12167.8 EHU00531.1 - 3e-20 71.9 0.1 9.5e-20 70.3 0.0 1.9 2 0 0 2 2 2 1 Arm DNA-binding domain Phage_integrase PF00589.22 EHU00531.1 - 2e-19 70.0 0.0 4.3e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family FliE PF02049.18 EHU00532.1 - 1.9e-28 98.4 7.2 2.4e-28 98.1 7.2 1.1 1 0 0 1 1 1 1 Flagellar hook-basal body complex protein FliE YscJ_FliF PF01514.17 EHU00533.1 - 1.4e-78 263.0 2.4 3.1e-77 258.6 0.0 2.9 3 1 1 4 4 4 1 Secretory protein of YscJ/FliF family YscJ_FliF_C PF08345.11 EHU00533.1 - 9.1e-47 159.2 21.0 9.1e-47 159.2 21.0 3.1 3 1 0 3 3 3 1 Flagellar M-ring protein C-terminal DUF3272 PF11676.8 EHU00533.1 - 0.001 19.3 0.1 0.0021 18.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3272) CbtA PF09490.10 EHU00533.1 - 0.025 14.4 0.3 0.025 14.4 0.3 1.7 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) Ectoine_synth PF06339.12 EHU00533.1 - 0.064 13.5 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Ectoine synthase DUF1206 PF06724.11 EHU00533.1 - 0.22 11.7 0.9 3.5 7.8 0.2 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) FliG_C PF01706.16 EHU00534.1 - 5.3e-38 129.5 17.3 5.8e-36 123.0 4.9 3.6 2 1 2 4 4 4 2 FliG C-terminal domain FliG_N PF14842.6 EHU00534.1 - 5.4e-36 123.3 16.4 6.2e-32 110.2 3.0 3.5 2 1 1 3 3 3 2 FliG N-terminal domain FliG_M PF14841.6 EHU00534.1 - 1.1e-28 99.3 9.1 5.1e-24 84.3 0.1 3.9 3 1 0 3 3 3 2 FliG middle domain MgtE_N PF03448.17 EHU00534.1 - 3e-06 27.8 19.8 0.2 12.3 2.4 4.8 2 2 2 4 4 4 4 MgtE intracellular N domain DUF3654 PF12376.8 EHU00534.1 - 0.057 13.6 2.2 0.15 12.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3654) DUF1018 PF06252.12 EHU00534.1 - 0.35 11.9 2.3 3 8.9 0.3 3.0 2 2 0 2 2 2 0 Protein of unknown function (DUF1018) FliH PF02108.16 EHU00535.1 - 1.9e-39 134.6 0.1 1.9e-39 134.6 0.1 1.7 2 0 0 2 2 2 1 Flagellar assembly protein FliH Yae1_N PF09811.9 EHU00535.1 - 0.026 14.2 10.1 0.063 13.0 10.1 1.7 1 0 0 1 1 1 0 Essential protein Yae1, N terminal DUF4407 PF14362.6 EHU00535.1 - 0.11 11.9 4.7 0.14 11.5 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.14 EHU00535.1 - 0.22 11.9 10.7 0.33 11.3 10.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Nbl1_Borealin_N PF10444.9 EHU00535.1 - 2 8.1 6.2 0.13 11.9 0.5 1.9 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal ATP-synt_ab PF00006.25 EHU00536.1 - 8.7e-71 237.9 0.0 1.1e-70 237.6 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain T3SS_ATPase_C PF18269.1 EHU00536.1 - 7.3e-24 83.4 0.2 1.2e-23 82.7 0.2 1.4 1 0 0 1 1 1 1 T3SS EscN ATPase C-terminal domain ABC_tran PF00005.27 EHU00536.1 - 0.13 12.8 0.1 0.27 11.7 0.1 1.5 1 0 0 1 1 1 0 ABC transporter FliJ PF02050.16 EHU00537.1 - 5.4e-32 110.6 21.9 6.5e-32 110.3 21.9 1.1 1 0 0 1 1 1 1 Flagellar FliJ protein Exonuc_VII_L PF02601.15 EHU00537.1 - 0.011 15.3 10.8 0.012 15.2 10.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Sulfatase_C PF14707.6 EHU00537.1 - 0.023 15.4 0.7 0.043 14.5 0.4 1.5 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase FANCI_S2 PF14676.6 EHU00537.1 - 0.045 14.1 0.1 0.052 13.8 0.1 1.2 1 0 0 1 1 1 0 FANCI solenoid 2 OEP PF02321.18 EHU00537.1 - 0.23 11.3 21.8 0.028 14.2 12.4 2.0 2 0 0 2 2 2 0 Outer membrane efflux protein MscS_porin PF12795.7 EHU00537.1 - 0.24 10.9 22.7 0.65 9.5 22.7 1.6 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Bestrophin PF01062.21 EHU00537.1 - 0.26 10.6 2.4 0.33 10.3 2.4 1.1 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel RasGAP_C PF03836.15 EHU00537.1 - 0.26 11.4 10.7 0.88 9.7 5.8 2.6 1 1 1 2 2 2 0 RasGAP C-terminus FliT PF05400.13 EHU00537.1 - 0.48 11.3 15.7 0.38 11.6 0.6 3.2 1 1 2 3 3 3 0 Flagellar protein FliT IZUMO PF15005.6 EHU00537.1 - 1.2 9.6 4.5 1.2 9.6 2.7 1.8 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated FAA_hydro_N_2 PF18288.1 EHU00537.1 - 1.4 9.4 5.5 2.5 8.6 3.2 2.3 1 1 2 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 DUF745 PF05335.13 EHU00537.1 - 1.8 8.3 10.9 4 7.1 11.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF745) LMBR1 PF04791.16 EHU00537.1 - 1.9 7.3 6.0 2.1 7.1 6.0 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Fib_alpha PF08702.10 EHU00537.1 - 3 8.0 7.4 1.7 8.8 5.1 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Flg_hook PF02120.16 EHU00538.1 - 2.6e-21 75.3 2.9 7.1e-21 73.9 2.9 1.8 1 0 0 1 1 1 1 Flagellar hook-length control protein FliK FliL PF03748.14 EHU00539.1 - 1.2e-22 80.4 0.0 1.6e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Flagellar basal body-associated protein FliL Myco_arth_vir_N PF09610.10 EHU00539.1 - 0.12 12.5 1.0 0.12 12.5 1.0 1.7 2 0 0 2 2 2 0 Mycoplasma virulence signal region (Myco_arth_vir_N) FliM PF02154.15 EHU00540.1 - 1.5e-78 263.1 0.0 2.4e-78 262.5 0.0 1.3 1 0 0 1 1 1 1 Flagellar motor switch protein FliM FliMN_C PF01052.20 EHU00540.1 - 6e-16 58.2 0.0 1.1e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Type III flagellar switch regulator (C-ring) FliN C-term FliMN_C PF01052.20 EHU00541.1 - 3.3e-27 94.3 1.6 4.3e-27 93.9 1.6 1.2 1 0 0 1 1 1 1 Type III flagellar switch regulator (C-ring) FliN C-term FliN_N PF16973.5 EHU00541.1 - 1.2e-20 73.0 6.1 1.8e-20 72.5 6.1 1.3 1 0 0 1 1 1 1 Flagellar motor switch protein FliN N-terminal p450 PF00067.22 EHU00541.1 - 0.013 14.3 0.0 0.016 13.9 0.0 1.1 1 0 0 1 1 1 0 Cytochrome P450 FliO PF04347.13 EHU00542.1 - 6.4e-19 68.0 0.2 9.1e-19 67.6 0.2 1.2 1 0 0 1 1 1 1 Flagellar biosynthesis protein, FliO MLANA PF14991.6 EHU00542.1 - 0.014 15.7 0.0 0.016 15.5 0.0 1.3 1 0 0 1 1 1 0 Protein melan-A FliP PF00813.20 EHU00543.1 - 2.8e-77 258.9 12.5 3.6e-77 258.6 12.5 1.1 1 0 0 1 1 1 1 FliP family Bac_export_3 PF01313.19 EHU00544.1 - 1.2e-29 102.0 6.2 1.4e-29 101.8 6.2 1.0 1 0 0 1 1 1 1 Bacterial export proteins, family 3 Bac_export_1 PF01311.20 EHU00544.1 - 0.0083 15.7 5.6 0.01 15.4 5.6 1.0 1 0 0 1 1 1 1 Bacterial export proteins, family 1 BacA PF02673.18 EHU00544.1 - 0.01 15.6 1.8 0.011 15.4 1.8 1.0 1 0 0 1 1 1 0 Bacitracin resistance protein BacA DUF4235 PF14019.6 EHU00544.1 - 0.15 12.2 0.4 0.15 12.2 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) TM_helix PF05552.12 EHU00544.1 - 2.7 8.0 8.3 1.3 9.0 0.2 2.9 2 1 1 3 3 3 0 Conserved TM helix Bac_export_1 PF01311.20 EHU00545.1 - 2e-68 230.4 33.9 2.3e-68 230.2 33.9 1.0 1 0 0 1 1 1 1 Bacterial export proteins, family 1 GerE PF00196.19 EHU00546.1 - 2.1e-17 62.4 1.8 4.6e-17 61.3 1.8 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Myc-LZ PF02344.15 EHU00546.1 - 0.0087 16.1 0.1 0.018 15.2 0.1 1.5 1 0 0 1 1 1 1 Myc leucine zipper domain HTH_40 PF14493.6 EHU00546.1 - 0.045 14.2 1.8 0.11 12.9 0.3 2.4 2 1 0 2 2 2 0 Helix-turn-helix domain MCPsignal PF00015.21 EHU00547.1 - 5.3e-56 189.1 30.8 3e-55 186.7 21.3 3.0 3 0 0 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain TarH PF02203.15 EHU00547.1 - 1.3e-26 93.6 0.1 1.3e-26 93.6 0.1 3.8 4 0 0 4 4 4 1 Tar ligand binding domain homologue HAMP PF00672.25 EHU00547.1 - 8e-10 38.9 5.6 1.4e-09 38.2 0.3 3.8 3 2 0 3 3 3 1 HAMP domain DUF1664 PF07889.12 EHU00547.1 - 0.011 15.8 11.9 1.7 8.7 3.1 4.6 3 2 2 5 5 5 0 Protein of unknown function (DUF1664) OSCP PF00213.18 EHU00547.1 - 0.039 14.1 0.4 0.039 14.1 0.4 3.3 2 1 0 3 3 3 0 ATP synthase delta (OSCP) subunit BLOC1_2 PF10046.9 EHU00547.1 - 0.09 13.1 13.8 7 7.0 0.2 5.0 3 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-H PF05837.12 EHU00547.1 - 0.66 10.4 11.5 3.2 8.2 1.8 3.6 3 0 0 3 3 3 0 Centromere protein H (CENP-H) DUF745 PF05335.13 EHU00547.1 - 0.67 9.6 33.6 0.78 9.4 18.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF745) UPF0242 PF06785.11 EHU00547.1 - 1.1 9.4 3.4 5.2 7.1 0.4 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Fib_alpha PF08702.10 EHU00547.1 - 3.3 7.9 10.3 5.5 7.2 0.3 3.3 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Prominin PF05478.11 EHU00547.1 - 5.1 4.9 9.1 1.4 6.8 2.9 2.3 1 1 1 2 2 2 0 Prominin DSRB PF10781.9 EHU00548.1 - 9.1e-37 124.5 0.2 1.1e-36 124.3 0.2 1.0 1 0 0 1 1 1 1 Dextransucrase DSRB Pmp3 PF01679.17 EHU00549.1 - 3.8e-22 78.2 8.9 4.1e-22 78.1 8.9 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF4191 PF13829.6 EHU00549.1 - 1.1 8.5 3.1 1.1 8.5 3.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF2525 PF10733.9 EHU00550.1 - 0.00013 22.2 0.0 0.00017 21.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2525) Hydrolase_3 PF08282.12 EHU00551.1 - 1.1e-21 77.7 0.0 1.3e-19 70.9 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EHU00551.1 - 6.3e-12 45.5 0.0 6.5e-07 29.1 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Trehalose_PPase PF02358.16 EHU00551.1 - 0.00044 19.5 0.0 0.0017 17.6 0.0 1.8 2 0 0 2 2 2 1 Trehalose-phosphatase Hydrolase PF00702.26 EHU00551.1 - 0.12 12.6 0.1 0.45 10.8 0.1 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EHU00551.1 - 0.15 12.1 0.0 0.94 9.5 0.0 2.0 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF2158 PF09926.9 EHU00553.1 - 0.0014 18.3 0.0 0.0017 18.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized small protein (DUF2158) LA-virus_coat PF09220.10 EHU00553.1 - 0.039 12.6 0.0 0.039 12.6 0.0 1.0 1 0 0 1 1 1 0 L-A virus, major coat protein DUF808 PF05661.12 EHU00555.1 - 2.4e-113 378.2 10.9 2.8e-113 378.0 10.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF808) Vsr PF03852.15 EHU00557.1 - 1.3e-30 105.0 0.1 2.3e-30 104.2 0.1 1.4 1 0 0 1 1 1 1 DNA mismatch endonuclease Vsr MTES_1575 PF18741.1 EHU00557.1 - 0.029 14.6 0.4 0.37 11.0 0.4 2.2 1 1 0 1 1 1 0 REase_MTES_1575 DUF5615 PF18480.1 EHU00557.1 - 0.089 12.6 0.1 9 6.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5615) DNA_methylase PF00145.17 EHU00558.1 - 3e-74 250.3 0.0 3.9e-74 250.0 0.0 1.1 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase DNA_meth_N PF18284.1 EHU00558.1 - 2.8e-14 52.8 0.0 1.7e-13 50.2 0.0 2.2 2 0 0 2 2 2 1 DNA methylase N-terminal domain MCPsignal PF00015.21 EHU00559.1 - 1.1e-27 96.9 18.2 2.5e-26 92.5 8.8 2.6 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain TarH PF02203.15 EHU00559.1 - 2.3e-22 79.7 4.3 2.3e-22 79.7 4.3 4.1 4 1 0 5 5 5 1 Tar ligand binding domain homologue IFT57 PF10498.9 EHU00559.1 - 0.0046 16.0 10.6 0.0086 15.1 3.2 2.4 2 0 0 2 2 2 2 Intra-flagellar transport protein 57 EzrA PF06160.12 EHU00559.1 - 0.011 14.0 9.0 0.11 10.6 0.4 2.5 3 0 0 3 3 3 0 Septation ring formation regulator, EzrA Corona_S2 PF01601.16 EHU00559.1 - 0.48 8.9 15.2 0.021 13.3 3.5 2.4 3 0 0 3 3 3 0 Coronavirus S2 glycoprotein Fez1 PF06818.15 EHU00559.1 - 0.52 10.7 7.2 6.9 7.1 0.9 2.5 2 0 0 2 2 2 0 Fez1 DUF948 PF06103.11 EHU00559.1 - 1.4 9.2 17.7 5.3 7.4 0.2 5.3 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 EHU00559.1 - 1.6 8.8 19.0 3.1 7.8 3.8 4.0 3 2 2 5 5 5 0 Laminin Domain II DUF1664 PF07889.12 EHU00559.1 - 1.7 8.7 13.3 10 6.2 1.1 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 EHU00559.1 - 2 9.0 10.2 0.77 10.3 0.6 2.9 2 1 0 2 2 2 0 Protein of unknown function DUF16 PP_kinase_N PF13089.6 EHU00559.1 - 3.7 7.9 10.1 0.7 10.2 0.1 3.4 3 2 0 3 3 3 0 Polyphosphate kinase N-terminal domain DUF489 PF04356.12 EHU00559.1 - 4.6 7.2 12.7 6.7 6.7 1.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF489) Spc7 PF08317.11 EHU00559.1 - 5.6 5.8 13.6 7 5.4 2.1 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein Fib_alpha PF08702.10 EHU00559.1 - 6.1 7.0 11.2 1.5 9.0 0.4 2.9 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family NifQ PF04891.12 EHU00559.1 - 6.3 7.1 6.3 8.5 6.7 0.5 2.5 2 0 0 2 2 2 0 NifQ Arc PF03869.14 EHU00560.1 - 6e-05 22.8 0.1 0.00013 21.8 0.1 1.4 1 0 0 1 1 1 1 Arc-like DNA binding domain RHH_1 PF01402.21 EHU00560.1 - 0.014 15.3 0.1 0.038 13.9 0.0 1.8 2 1 0 2 2 2 0 Ribbon-helix-helix protein, copG family HD PF01966.22 EHU00561.1 - 1.7e-10 41.2 0.0 3.3e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 HD domain Peptidase_M90 PF06167.12 EHU00563.1 - 8.1e-64 215.6 0.0 9.5e-64 215.3 0.0 1.0 1 0 0 1 1 1 1 Glucose-regulated metallo-peptidase M90 DDE_Tnp_IS66 PF03050.14 EHU00564.1 - 4.8e-30 105.0 2.2 1.7e-28 99.9 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family zf-IS66 PF13005.7 EHU00564.1 - 6.6e-15 55.2 1.5 1.5e-14 54.1 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU00564.1 - 4.6e-12 46.5 9.0 9.8e-12 45.5 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHU00564.1 - 0.0057 16.4 6.2 0.0083 15.9 6.2 1.1 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B Csm1_N PF18504.1 EHU00564.1 - 0.0093 16.3 5.3 0.041 14.2 0.6 2.5 1 1 1 2 2 2 1 Csm1 N-terminal domain Exonuc_VII_L PF02601.15 EHU00564.1 - 0.0093 15.6 0.6 0.011 15.3 0.6 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit Phage_HK97_TLTM PF06120.11 EHU00564.1 - 0.011 15.0 1.7 0.017 14.3 1.7 1.2 1 0 0 1 1 1 0 Tail length tape measure protein FUSC PF04632.12 EHU00564.1 - 0.017 13.7 6.9 0.021 13.4 6.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Troponin PF00992.20 EHU00564.1 - 0.023 15.0 3.1 0.039 14.2 3.1 1.3 1 0 0 1 1 1 0 Troponin LXG PF04740.12 EHU00564.1 - 0.031 14.0 2.9 0.15 11.8 0.5 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily Tho2 PF11262.8 EHU00564.1 - 0.038 13.2 1.2 0.054 12.7 1.2 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 ERM PF00769.19 EHU00564.1 - 0.079 12.8 11.1 0.11 12.3 11.1 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Zn-ribbon_8 PF09723.10 EHU00564.1 - 0.11 12.7 1.7 0.5 10.5 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain DHR10 PF18595.1 EHU00564.1 - 0.15 12.1 10.9 0.24 11.5 10.9 1.2 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain RD3 PF14473.6 EHU00564.1 - 0.19 11.6 2.2 0.36 10.7 2.2 1.4 1 0 0 1 1 1 0 RD3 protein TMPIT PF07851.13 EHU00564.1 - 0.45 9.7 3.1 0.64 9.2 3.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein PCRF PF03462.18 EHU00564.1 - 0.52 10.1 3.8 0.8 9.5 3.8 1.2 1 0 0 1 1 1 0 PCRF domain USP8_interact PF08941.10 EHU00564.1 - 0.62 9.8 3.5 3.3 7.5 3.7 2.0 2 1 0 2 2 2 0 USP8 interacting HAUS-augmin3 PF14932.6 EHU00564.1 - 0.92 9.0 7.8 2 7.9 7.8 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF1192 PF06698.11 EHU00564.1 - 1.2 9.3 8.3 1.6 8.8 0.2 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF1192) OmpH PF03938.14 EHU00564.1 - 1.7 9.0 8.0 2.6 8.4 8.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HalX PF08663.10 EHU00564.1 - 2.6 8.5 8.1 0.24 11.8 3.1 1.8 2 0 0 2 2 2 0 HalX domain SlyX PF04102.12 EHU00564.1 - 3.5 8.3 9.4 3.9 8.2 1.3 2.8 1 1 1 2 2 2 0 SlyX MerR-DNA-bind PF09278.11 EHU00564.1 - 3.8 8.1 9.9 4.6 7.8 0.5 2.6 2 0 0 2 2 2 0 MerR, DNA binding TMF_DNA_bd PF12329.8 EHU00564.1 - 4.4 7.4 8.5 4.2 7.4 0.6 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding TnpB_IS66 PF05717.13 EHU00565.1 - 8.6e-12 44.9 0.0 9.4e-12 44.7 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHU00566.1 - 2.9e-09 37.1 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU00566.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU00566.1 - 0.072 13.2 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU00566.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix MarC PF01914.17 EHU00567.1 - 1.7e-70 236.5 11.8 2e-70 236.4 11.8 1.0 1 0 0 1 1 1 1 MarC family integral membrane protein YrvL PF14184.6 EHU00567.1 - 6.9 6.8 12.4 4.6 7.4 1.4 2.6 3 0 0 3 3 3 0 Regulatory protein YrvL Fe-ADH PF00465.19 EHU00568.1 - 1.1e-114 383.1 0.7 1.6e-114 382.5 0.7 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Aldedh PF00171.22 EHU00568.1 - 1.6e-27 96.2 3.8 2.6e-25 88.9 4.3 2.1 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Fe-ADH_2 PF13685.6 EHU00568.1 - 6e-19 68.7 0.3 4.4e-08 33.1 0.6 2.5 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase HTH_AsnC-type PF13404.6 EHU00568.1 - 0.24 11.2 1.5 1.2 9.0 0.0 2.9 4 0 0 4 4 4 0 AsnC-type helix-turn-helix domain TK PF00265.18 EHU00569.1 - 6.7e-62 208.5 0.0 7.6e-62 208.3 0.0 1.0 1 0 0 1 1 1 1 Thymidine kinase KdpD PF02702.17 EHU00569.1 - 0.0098 15.4 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 Osmosensitive K+ channel His kinase sensor domain AAA_22 PF13401.6 EHU00569.1 - 0.016 15.5 0.1 0.031 14.6 0.1 1.4 1 1 0 1 1 1 0 AAA domain Histone_HNS PF00816.21 EHU00570.1 - 3.5e-19 69.4 7.2 7.6e-19 68.3 3.5 2.0 1 1 1 2 2 2 2 H-NS histone family UCMA PF17085.5 EHU00570.1 - 0.0026 17.8 0.8 0.0048 16.9 0.8 1.5 1 0 0 1 1 1 1 Unique cartilage matrix associated protein DUF615 PF04751.14 EHU00570.1 - 0.046 13.7 2.2 0.06 13.3 2.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF615) Fez1 PF06818.15 EHU00570.1 - 0.052 14.0 4.4 0.063 13.7 4.4 1.0 1 0 0 1 1 1 0 Fez1 STAT_alpha PF01017.20 EHU00570.1 - 0.055 13.4 0.6 0.074 13.0 0.6 1.2 1 0 0 1 1 1 0 STAT protein, all-alpha domain FAD_binding_3 PF01494.19 EHU00570.1 - 0.056 12.7 0.2 0.071 12.3 0.2 1.1 1 0 0 1 1 1 0 FAD binding domain DUF3037 PF11236.8 EHU00570.1 - 0.058 13.8 1.0 0.1 13.0 0.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3037) Spem1 PF15670.5 EHU00570.1 - 0.059 12.9 0.1 0.066 12.8 0.1 1.0 1 0 0 1 1 1 0 Spermatid maturation protein 1 HTH_WhiA PF02650.14 EHU00570.1 - 0.063 13.6 0.5 0.18 12.1 0.4 1.8 2 0 0 2 2 2 0 WhiA C-terminal HTH domain DUF1028 PF06267.12 EHU00570.1 - 0.11 12.2 0.1 0.18 11.6 0.0 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF1028) GDP_Man_Dehyd PF16363.5 EHU00571.1 - 2.9e-59 201.1 0.0 3.4e-59 200.9 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EHU00571.1 - 2.1e-56 191.1 0.1 2.4e-56 190.9 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EHU00571.1 - 9.4e-20 70.8 0.0 1.2e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EHU00571.1 - 1.5e-15 57.1 0.0 2.9e-15 56.1 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EHU00571.1 - 5.9e-14 51.9 0.0 6e-13 48.6 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EHU00571.1 - 1.6e-08 34.2 0.1 4.5e-08 32.8 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 EHU00571.1 - 2.1e-07 31.0 0.0 4.9e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EHU00571.1 - 9e-07 28.3 0.1 0.00024 20.4 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein KR PF08659.10 EHU00571.1 - 3e-05 24.0 0.0 6.5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EHU00571.1 - 0.012 15.2 0.2 0.02 14.5 0.1 1.4 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 EHU00571.1 - 0.023 14.3 0.1 0.037 13.6 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family UDPG_MGDP_dh_N PF03721.14 EHU00572.1 - 3.7e-64 215.8 0.8 6e-64 215.1 0.8 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 EHU00572.1 - 7.7e-40 135.0 0.0 1.5e-39 134.1 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 EHU00572.1 - 9.9e-30 103.1 0.0 4.2e-29 101.1 0.0 2.1 2 1 1 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.15 EHU00572.1 - 0.0002 21.6 0.2 1.2 9.3 0.0 2.9 3 0 0 3 3 3 2 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 EHU00572.1 - 0.00034 20.5 0.0 0.001 19.0 0.0 1.8 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EHU00572.1 - 0.0034 16.7 0.4 0.0061 15.9 0.4 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 EHU00572.1 - 0.0042 17.3 1.9 0.029 14.6 0.1 2.8 2 1 0 2 2 2 1 TrkA-N domain NAD_binding_11 PF14833.6 EHU00572.1 - 0.0084 16.4 0.0 0.075 13.3 0.0 2.2 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase ApbA PF02558.16 EHU00572.1 - 0.016 14.9 0.0 0.038 13.6 0.0 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 EHU00572.1 - 0.037 14.5 0.3 1.4 9.4 0.2 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.23 EHU00572.1 - 0.083 12.9 0.1 0.4 10.6 0.0 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.19 EHU00572.1 - 0.1 11.8 0.1 0.18 11.0 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 EHU00572.1 - 0.16 12.5 0.4 0.5 11.0 0.4 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NTP_transferase PF00483.23 EHU00573.1 - 2.1e-25 89.8 0.0 2.7e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EHU00573.1 - 7.3e-07 29.7 0.0 1.5e-06 28.7 0.0 1.4 1 1 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 EHU00573.1 - 0.0029 17.4 0.0 0.0081 15.9 0.0 1.6 2 0 0 2 2 2 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.19 EHU00573.1 - 0.014 15.4 0.1 0.023 14.6 0.1 1.3 1 0 0 1 1 1 0 Cytidylyltransferase Response_reg PF00072.24 EHU00574.1 - 4.9e-29 100.8 0.1 9.5e-29 99.8 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain SpoIIE PF07228.12 EHU00574.1 - 0.0013 18.7 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) BRCT_3 PF18428.1 EHU00574.1 - 0.0042 17.1 0.0 0.046 13.8 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Patatin PF01734.22 EHU00575.1 - 2.6e-24 86.5 0.1 6.1e-24 85.3 0.1 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase UPF0225 PF17775.1 EHU00576.1 - 2.1e-30 105.4 0.3 2.5e-30 105.2 0.3 1.1 1 0 0 1 1 1 1 UPF0225 domain SEC-C PF02810.15 EHU00576.1 - 1.2e-11 44.2 29.9 8.1e-07 28.8 11.4 2.2 2 0 0 2 2 2 2 SEC-C motif Formyl_trans_N PF00551.19 EHU00577.1 - 1.3e-51 174.9 0.0 1.7e-51 174.6 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 EHU00577.1 - 4.6e-07 29.5 0.0 1.1e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 ACT domain Exo_endo_phos PF03372.23 EHU00578.1 - 1.2e-21 77.4 0.1 1.7e-21 76.8 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 EHU00578.1 - 0.044 13.6 0.0 0.89 9.4 0.0 2.2 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase DUF1496 PF07383.12 EHU00579.1 - 2.1e-24 84.8 3.8 3.1e-24 84.3 3.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1496) IGFL PF14653.6 EHU00579.1 - 0.013 15.5 0.2 0.017 15.1 0.2 1.3 1 0 0 1 1 1 0 Insulin growth factor-like family Topoisom_bac PF01131.20 EHU00580.1 - 1.3e-113 380.2 0.0 1.5e-113 379.9 0.0 1.0 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 EHU00580.1 - 4e-16 59.1 0.0 1e-15 57.8 0.0 1.8 1 0 0 1 1 1 1 Toprim domain FYRC PF05965.14 EHU00580.1 - 0.041 14.0 0.0 0.42 10.8 0.0 2.3 2 0 0 2 2 2 0 F/Y rich C-terminus Nitroreductase PF00881.24 EHU00581.1 - 1.2e-24 87.2 0.1 1.4e-24 87.0 0.1 1.0 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 EHU00581.1 - 0.12 11.9 0.0 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 Putative TM nitroreductase Peptidase_S49 PF01343.18 EHU00582.1 - 5.1e-91 302.6 1.0 3.2e-48 163.6 0.1 2.8 3 0 0 3 3 3 2 Peptidase family S49 CLP_protease PF00574.23 EHU00582.1 - 2.8e-06 27.3 0.3 9.4e-05 22.4 0.3 2.3 2 0 0 2 2 2 1 Clp protease Peptidase_S41 PF03572.18 EHU00582.1 - 0.0019 17.8 0.2 0.0073 15.9 0.0 2.0 2 1 0 2 2 2 1 Peptidase family S41 SDH_sah PF01972.16 EHU00582.1 - 0.0019 17.3 0.2 0.0036 16.4 0.2 1.4 1 0 0 1 1 1 1 Serine dehydrogenase proteinase TED PF08341.11 EHU00582.1 - 0.023 15.0 0.2 0.18 12.2 0.0 2.2 2 0 0 2 2 2 0 Thioester domain Asparaginase PF00710.20 EHU00583.1 - 8.9e-64 214.6 0.0 1.3e-63 214.1 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EHU00583.1 - 4.3e-32 110.7 0.0 9.6e-32 109.6 0.0 1.6 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Isochorismatase PF00857.20 EHU00584.1 - 9e-33 113.9 0.0 1.1e-32 113.6 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DUF1315 PF07023.12 EHU00585.1 - 3.3e-27 94.4 0.4 4e-27 94.1 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1315) LZ3wCH PF18517.1 EHU00585.1 - 0.004 17.2 0.1 0.0067 16.5 0.1 1.4 1 0 0 1 1 1 1 Leucine zipper with capping helix domain PAP_central PF04928.17 EHU00585.1 - 0.069 12.1 0.0 0.076 12.0 0.0 1.1 1 0 0 1 1 1 0 Poly(A) polymerase central domain SelR PF01641.18 EHU00586.1 - 1.4e-52 176.9 0.0 1.6e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 EHU00586.1 - 0.017 15.4 0.1 0.039 14.2 0.1 1.7 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_10 PF10058.9 EHU00586.1 - 0.023 14.4 0.3 0.54 10.0 0.1 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-B_box PF00643.24 EHU00586.1 - 0.082 13.1 0.8 11 6.3 0.2 2.3 2 0 0 2 2 2 0 B-box zinc finger Gp_dh_C PF02800.20 EHU00587.1 - 6.5e-71 237.0 0.0 9.2e-71 236.6 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EHU00587.1 - 2.6e-42 143.3 1.3 1.5e-41 140.8 0.3 2.1 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 EHU00587.1 - 0.00032 20.8 1.7 0.0027 17.8 1.7 2.4 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 EHU00587.1 - 0.014 14.7 0.0 0.081 12.3 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF2656 PF10847.8 EHU00587.1 - 0.085 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2656) Aldose_epim PF01263.20 EHU00588.1 - 1.2e-42 146.3 0.0 1.4e-42 146.0 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Aldo_ket_red PF00248.21 EHU00589.1 - 1.2e-55 188.8 0.0 1.4e-54 185.3 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family PreAtp-grasp PF18604.1 EHU00589.1 - 0.097 12.3 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Pre ATP-grasp domain MipA PF06629.12 EHU00590.1 - 1.6e-55 188.7 8.3 1.8e-55 188.5 8.3 1.0 1 0 0 1 1 1 1 MltA-interacting protein MipA OMP_b-brl PF13505.6 EHU00590.1 - 0.027 14.6 6.7 0.039 14.1 4.3 1.9 1 1 1 2 2 2 0 Outer membrane protein beta-barrel domain AAA_PrkA PF08298.11 EHU00591.1 - 3.1e-177 588.9 0.0 4.2e-177 588.4 0.0 1.2 1 0 0 1 1 1 1 PrkA AAA domain PrkA PF06798.12 EHU00591.1 - 3.1e-72 243.3 1.6 6.2e-72 242.3 1.6 1.5 1 0 0 1 1 1 1 PrkA serine protein kinase C-terminal domain AAA_16 PF13191.6 EHU00591.1 - 3.1e-05 24.4 0.0 0.00012 22.6 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EHU00591.1 - 0.0025 17.8 0.1 0.023 14.7 0.0 2.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EHU00591.1 - 0.0093 16.2 0.0 0.045 14.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain CobU PF02283.16 EHU00591.1 - 0.049 13.2 0.1 4 7.0 0.0 2.5 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Mg_chelatase PF01078.21 EHU00591.1 - 0.1 11.9 0.0 0.34 10.2 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF444 PF04285.12 EHU00592.1 - 1.1e-185 617.7 3.9 1.3e-185 617.5 3.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF444) Na_H_Exchanger PF00999.21 EHU00593.1 - 1.3e-55 188.7 46.0 1.7e-55 188.4 46.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CorC_HlyC PF03471.17 EHU00593.1 - 3.4e-15 55.8 0.0 5.8e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Transporter associated domain TrkA_C PF02080.21 EHU00593.1 - 5.6e-10 38.9 0.0 1.1e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 TrkA-C domain HTH_Tnp_IS1 PF12759.7 EHU00594.1 - 2.6e-18 65.3 1.0 2.8e-18 65.2 1.0 1.0 1 0 0 1 1 1 1 InsA C-terminal domain HTH_Tnp_ISL3 PF13542.6 EHU00594.1 - 0.035 13.5 0.0 0.035 13.5 0.0 1.0 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 EHU00594.1 - 0.11 12.3 0.0 0.11 12.3 0.0 1.0 1 0 0 1 1 1 0 Homeodomain-like domain DDE_Tnp_IS1 PF03400.13 EHU00595.1 - 2.1e-36 125.1 0.4 2.3e-36 125.0 0.4 1.0 1 0 0 1 1 1 1 IS1 transposase Bac_transf PF02397.16 EHU00596.1 - 3.2e-63 212.7 0.0 7.4e-63 211.5 0.0 1.6 2 0 0 2 2 2 1 Bacterial sugar transferase CoA_binding_3 PF13727.6 EHU00596.1 - 2.8e-07 30.7 0.4 5.9e-07 29.7 0.4 1.6 1 0 0 1 1 1 1 CoA-binding domain PglD_N PF17836.1 EHU00596.1 - 0.086 13.5 0.1 0.17 12.6 0.1 1.4 1 0 0 1 1 1 0 PglD N-terminal domain MFS_1 PF07690.16 EHU00597.1 - 1.8e-39 135.7 44.0 1.8e-39 135.7 44.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EHU00597.1 - 3.1e-07 29.6 27.3 8.9e-06 24.8 11.3 3.0 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 EHU00597.1 - 1.3e-05 23.8 2.7 2e-05 23.2 2.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RskA PF10099.9 EHU00597.1 - 1.9 8.8 6.0 8.6 6.6 0.2 2.3 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Ala_racemase_N PF01168.20 EHU00598.1 - 3.6e-65 219.7 0.0 4.9e-65 219.2 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Ala_racemase_C PF00842.21 EHU00598.1 - 8.3e-42 141.9 0.2 1.4e-41 141.2 0.2 1.4 1 0 0 1 1 1 1 Alanine racemase, C-terminal domain DAO PF01266.24 EHU00599.1 - 8.8e-77 259.1 0.4 1.1e-76 258.8 0.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EHU00599.1 - 2.1e-08 33.8 0.1 5e-05 22.7 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EHU00599.1 - 2.5e-08 34.0 0.0 1.4e-06 28.4 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EHU00599.1 - 4.6e-08 33.5 0.0 3.3e-06 27.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EHU00599.1 - 1.8e-07 30.6 1.1 5.5e-06 25.7 1.1 2.2 1 1 0 1 1 1 1 FAD binding domain ApbA PF02558.16 EHU00599.1 - 2.3e-07 30.6 0.1 2.4e-05 24.0 0.1 2.3 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 EHU00599.1 - 3.3e-07 29.4 0.4 0.012 14.3 0.0 2.7 3 0 0 3 3 3 2 HI0933-like protein Amino_oxidase PF01593.24 EHU00599.1 - 1.3e-05 24.7 0.0 0.0019 17.6 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 EHU00599.1 - 0.0001 21.6 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 EHU00599.1 - 0.00014 21.2 0.3 0.00087 18.6 0.2 2.1 2 1 0 2 2 2 1 FAD binding domain UDPG_MGDP_dh_N PF03721.14 EHU00599.1 - 0.00025 20.7 0.0 0.00044 19.9 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 EHU00599.1 - 0.00049 20.0 0.1 0.001 19.0 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 EHU00599.1 - 0.00069 19.1 1.1 0.18 11.1 1.4 2.7 1 1 1 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EHU00599.1 - 0.0015 17.5 0.2 0.2 10.5 0.3 2.3 2 0 0 2 2 2 1 Tryptophan halogenase GIDA PF01134.22 EHU00599.1 - 0.0053 15.9 0.2 0.032 13.3 0.1 2.1 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EHU00599.1 - 0.01 15.1 0.0 2.6 7.2 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EHU00599.1 - 0.015 14.5 0.0 0.043 13.0 0.0 1.7 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.18 EHU00599.1 - 0.016 15.4 0.0 0.037 14.3 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain GDI PF00996.18 EHU00599.1 - 0.027 13.0 0.0 0.47 8.9 0.0 2.0 2 0 0 2 2 2 0 GDP dissociation inhibitor Glyco_transf_4 PF13439.6 EHU00599.1 - 0.027 14.5 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Sacchrp_dh_NADP PF03435.18 EHU00599.1 - 0.049 13.9 0.0 0.098 12.9 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 EHU00599.1 - 0.058 13.8 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding CbiA PF01656.23 EHU00599.1 - 0.098 12.7 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain XdhC_C PF13478.6 EHU00599.1 - 0.1 13.1 0.0 0.27 11.7 0.0 1.9 1 1 0 1 1 1 0 XdhC Rossmann domain NAD_binding_2 PF03446.15 EHU00599.1 - 0.12 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EHU00599.1 - 0.12 13.0 0.0 0.32 11.6 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.21 EHU00599.1 - 0.13 11.6 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 ThiF family NAD_Gly3P_dh_N PF01210.23 EHU00599.1 - 0.13 12.2 0.1 0.3 11.1 0.1 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus SpoVR PF04293.13 EHU00600.1 - 2.6e-177 589.7 10.2 3e-177 589.5 10.2 1.0 1 0 0 1 1 1 1 SpoVR like protein Peptidase_M1 PF01433.20 EHU00600.1 - 0.019 14.6 0.1 0.039 13.5 0.1 1.5 1 0 0 1 1 1 0 Peptidase family M1 domain DUF639 PF04842.12 EHU00600.1 - 0.065 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) FadR_C PF07840.12 EHU00601.1 - 7.6e-67 224.3 0.0 9.3e-67 224.0 0.0 1.1 1 0 0 1 1 1 1 FadR C-terminal domain GntR PF00392.21 EHU00601.1 - 4.6e-20 71.0 0.0 8e-20 70.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 EHU00601.1 - 3.2e-05 23.8 0.0 7.7e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain TrmB PF01978.19 EHU00601.1 - 3.5e-05 23.6 0.0 0.00037 20.3 0.0 2.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB FCD PF07729.12 EHU00601.1 - 0.00039 20.9 0.0 0.00079 19.8 0.0 1.6 2 0 0 2 2 2 1 FCD domain HTH_IclR PF09339.10 EHU00601.1 - 0.0013 18.5 1.5 0.059 13.2 0.2 2.9 3 0 0 3 3 3 1 IclR helix-turn-helix domain HTH_24 PF13412.6 EHU00601.1 - 0.0063 16.0 1.1 0.0098 15.4 0.1 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Fe_dep_repress PF01325.19 EHU00601.1 - 0.012 15.8 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Rrf2 PF02082.20 EHU00601.1 - 0.026 14.9 0.0 0.071 13.5 0.0 1.7 2 0 0 2 2 2 0 Transcriptional regulator PaaX PF07848.12 EHU00601.1 - 0.038 14.2 0.1 0.081 13.1 0.1 1.5 1 0 0 1 1 1 0 PaaX-like protein HTH_28 PF13518.6 EHU00601.1 - 0.04 14.0 0.2 0.2 11.8 0.1 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain MarR PF01047.22 EHU00601.1 - 0.067 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 MarR family DsbB PF02600.16 EHU00602.1 - 1.1e-41 142.7 13.4 1.3e-41 142.5 13.4 1.0 1 0 0 1 1 1 1 Disulfide bond formation protein DsbB DPM3 PF08285.11 EHU00602.1 - 0.81 9.9 6.7 0.35 11.1 0.3 2.6 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) CxxCxxCC PF03692.15 EHU00603.1 - 2.7e-07 31.2 11.5 5.2e-07 30.3 11.5 1.5 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain FAA_hydrolase PF01557.18 EHU00604.1 - 6.1e-55 186.3 0.0 7.3e-55 186.0 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family YcgL PF05166.13 EHU00605.1 - 1e-31 109.1 0.1 1.3e-31 108.8 0.1 1.1 1 0 0 1 1 1 1 YcgL domain MinC_N PF05209.13 EHU00606.1 - 1.3e-34 118.3 0.0 1.8e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 Septum formation inhibitor MinC, N-terminal domain MinC_C PF03775.16 EHU00606.1 - 1.5e-31 108.4 0.1 2.8e-31 107.5 0.1 1.5 1 0 0 1 1 1 1 Septum formation inhibitor MinC, C-terminal domain AAA_31 PF13614.6 EHU00607.1 - 4.6e-21 75.5 0.1 7.8e-21 74.8 0.1 1.3 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 EHU00607.1 - 2e-20 73.2 0.1 2.7e-20 72.7 0.1 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 EHU00607.1 - 1.1e-17 64.3 0.8 1.7e-16 60.4 0.8 2.5 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase ArsA_ATPase PF02374.15 EHU00607.1 - 3.8e-10 39.5 3.0 1.7e-09 37.3 2.1 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 EHU00607.1 - 9.2e-10 38.2 1.1 2e-09 37.1 1.1 1.5 1 1 0 1 1 1 1 ATPase MipZ CBP_BcsQ PF06564.12 EHU00607.1 - 3e-07 30.2 0.0 5.4e-07 29.3 0.0 1.6 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 EHU00607.1 - 1e-05 25.1 0.1 0.00073 19.1 0.1 2.5 2 1 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_24 PF13479.6 EHU00607.1 - 0.00041 20.1 0.0 0.00063 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.6 EHU00607.1 - 0.002 18.0 3.1 2.4 8.0 0.0 2.8 2 1 1 3 3 3 2 AAA domain CLP1_P PF16575.5 EHU00607.1 - 0.0035 17.2 0.2 0.0081 16.0 0.1 1.6 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop VirC1 PF07015.11 EHU00607.1 - 0.01 15.1 0.2 0.02 14.2 0.2 1.4 1 0 0 1 1 1 0 VirC1 protein SRP54 PF00448.22 EHU00607.1 - 0.011 15.3 2.0 0.022 14.4 1.2 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF87 PF01935.17 EHU00607.1 - 0.04 14.0 0.5 0.21 11.7 0.4 2.1 1 1 0 1 1 1 0 Helicase HerA, central domain CobA_CobO_BtuR PF02572.15 EHU00607.1 - 0.046 14.0 0.5 0.13 12.5 0.5 1.7 1 1 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP AAA_25 PF13481.6 EHU00607.1 - 0.46 10.0 2.7 1.4 8.5 2.2 2.0 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EHU00607.1 - 0.72 9.5 2.5 1.6 8.4 2.5 1.5 1 0 0 1 1 1 0 AAA domain MinE PF03776.14 EHU00608.1 - 8e-25 86.6 0.2 9.3e-25 86.4 0.2 1.1 1 0 0 1 1 1 1 Septum formation topological specificity factor MinE DNA_pol_A_exo1 PF01612.20 EHU00609.1 - 1.8e-41 141.8 0.0 2.9e-41 141.1 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 EHU00609.1 - 1.4e-12 47.4 1.3 2.6e-12 46.5 0.2 2.1 3 0 0 3 3 3 1 HRDC domain AMP-binding PF00501.28 EHU00610.1 - 1.3e-110 369.9 0.0 1.6e-110 369.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EHU00610.1 - 4.6e-21 75.6 5.0 7.1e-21 75.0 0.4 2.9 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 EHU00610.1 - 0.0066 16.7 0.0 0.018 15.3 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF4235 PF14019.6 EHU00610.1 - 0.073 13.2 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) Pept_S41_N PF18294.1 EHU00610.1 - 0.22 11.5 0.2 6.3 6.9 0.0 2.3 2 0 0 2 2 2 0 Peptidase S41 N-terminal domain Slp PF03843.13 EHU00611.1 - 1.2e-46 157.9 0.0 1.4e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Outer membrane lipoprotein Slp family Peptidase_M22 PF00814.25 EHU00612.1 - 1e-26 94.3 0.0 1.7e-26 93.5 0.0 1.3 1 0 0 1 1 1 1 Glycoprotease family IMPDH PF00478.25 EHU00612.1 - 0.13 11.2 0.1 0.16 10.9 0.1 1.1 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Helicase_C_2 PF13307.6 EHU00613.1 - 9.1e-35 120.3 0.0 1.7e-34 119.5 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 EHU00613.1 - 7.2e-08 32.6 0.3 3.8e-06 27.0 0.3 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EHU00613.1 - 2e-07 30.9 2.2 0.00011 22.1 0.2 3.4 4 0 0 4 4 4 2 DEAD/DEAH box helicase DEAD_2 PF06733.15 EHU00613.1 - 0.0012 18.5 0.0 0.0023 17.6 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 DUF2075 PF09848.9 EHU00613.1 - 0.0053 16.0 0.5 0.063 12.5 0.1 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 EHU00613.1 - 0.022 13.8 0.0 0.047 12.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Methyltransf_17 PF12692.7 EHU00613.1 - 0.041 13.9 0.0 0.098 12.7 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase UvrD-helicase PF00580.21 EHU00613.1 - 0.096 12.2 0.1 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DeoRC PF00455.22 EHU00613.1 - 0.11 12.5 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 DeoR C terminal sensor domain DUF938 PF06080.12 EHU00613.1 - 0.17 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) DUF4282 PF14110.6 EHU00614.1 - 0.082 13.7 8.5 0.092 13.5 8.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) GWT1 PF06423.12 EHU00614.1 - 0.82 9.8 3.7 1.1 9.4 2.9 1.6 1 1 0 1 1 1 0 GWT1 DUF4131 PF13567.6 EHU00614.1 - 2.9 7.5 4.9 3.1 7.4 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Ribonuc_L-PSP PF01042.21 EHU00615.1 - 1.3e-24 86.5 0.1 1.5e-24 86.4 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP PMC2NT PF08066.12 EHU00615.1 - 0.024 15.3 0.1 0.032 14.9 0.1 1.1 1 0 0 1 1 1 0 PMC2NT (NUC016) domain UPF0181 PF03701.14 EHU00616.1 - 2.4e-26 91.1 5.4 2.9e-26 90.9 5.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0181) PGM_PMM_IV PF00408.20 EHU00616.1 - 0.07 13.3 0.1 0.092 12.9 0.1 1.3 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain Chorismate_bind PF00425.18 EHU00617.1 - 9.7e-93 310.4 0.0 1.2e-92 310.1 0.0 1.1 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 EHU00617.1 - 8.5e-24 84.4 0.0 1.6e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region NUDIX PF00293.28 EHU00618.1 - 3.6e-16 59.4 0.0 5.7e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain SDH_alpha PF03313.15 EHU00619.1 - 5.1e-97 324.6 2.8 6.5e-97 324.3 2.8 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 EHU00619.1 - 1.4e-55 188.0 0.1 2.8e-55 186.9 0.1 1.5 1 0 0 1 1 1 1 Serine dehydratase beta chain EAL PF00563.20 EHU00620.1 - 9.8e-65 218.4 0.0 1.4e-64 217.9 0.0 1.2 1 0 0 1 1 1 1 EAL domain CSS-motif PF12792.7 EHU00620.1 - 1.5e-25 89.9 0.0 2.6e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 CSS motif domain associated with EAL DUF515 PF04415.12 EHU00620.1 - 0.22 9.9 0.0 0.33 9.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) TerC PF03741.16 EHU00621.1 - 4e-49 166.7 14.5 6.5e-49 166.1 14.5 1.3 1 0 0 1 1 1 1 Integral membrane protein TerC family CorC_HlyC PF03471.17 EHU00621.1 - 1.2e-15 57.2 0.2 4.7e-15 55.4 0.0 2.1 2 0 0 2 2 2 1 Transporter associated domain CBS PF00571.28 EHU00621.1 - 8.7e-06 26.1 1.5 0.014 15.8 0.1 2.8 2 0 0 2 2 2 2 CBS domain DUF3382 PF11862.8 EHU00621.1 - 0.19 12.0 0.1 0.19 12.0 0.1 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3382) CclA_1 PF16942.5 EHU00621.1 - 1 9.7 8.4 0.055 13.7 1.0 2.5 3 0 0 3 3 3 0 Putative cyclic bacteriocin PTSIIB_sorb PF03830.15 EHU00622.1 - 7.7e-55 185.2 2.0 1.1e-54 184.7 2.0 1.2 1 0 0 1 1 1 1 PTS system sorbose subfamily IIB component EIIA-man PF03610.16 EHU00622.1 - 1.6e-34 118.6 0.0 3.4e-34 117.6 0.0 1.6 1 0 0 1 1 1 1 PTS system fructose IIA component SL4P PF17618.2 EHU00622.1 - 0.033 14.2 0.0 0.084 12.9 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized Strongylid L4 protein Phage_CI_repr PF07022.13 EHU00622.1 - 0.084 13.0 0.0 8.6 6.5 0.0 2.4 2 0 0 2 2 2 0 Bacteriophage CI repressor helix-turn-helix domain Strep_SA_rep PF06696.11 EHU00622.1 - 3.7 7.7 5.0 21 5.2 0.1 2.4 2 0 0 2 2 2 0 Streptococcal surface antigen repeat EII-Sor PF03609.14 EHU00623.1 - 2.2e-76 256.3 40.2 2.5e-76 256.1 40.2 1.0 1 0 0 1 1 1 1 PTS system sorbose-specific iic component EIID-AGA PF03613.14 EHU00624.1 - 6.5e-110 366.5 1.1 7.4e-110 366.3 1.1 1.0 1 0 0 1 1 1 1 PTS system mannose/fructose/sorbose family IID component DUF986 PF06173.12 EHU00625.1 - 3.4e-59 199.2 0.9 3.8e-59 199.0 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF986) Na_Ca_ex PF01699.24 EHU00625.1 - 0.023 14.7 3.6 0.023 14.7 3.6 1.8 2 0 0 2 2 2 0 Sodium/calcium exchanger protein Methyltransf_31 PF13847.6 EHU00626.1 - 1.9e-13 50.5 0.0 3.3e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EHU00626.1 - 2e-13 50.9 0.0 4.7e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EHU00626.1 - 2.9e-13 50.3 0.1 2e-12 47.6 0.1 2.3 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EHU00626.1 - 1.2e-07 31.4 0.0 2.1e-07 30.6 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EHU00626.1 - 6.7e-05 22.8 0.0 0.0013 18.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EHU00626.1 - 9.1e-05 22.1 0.0 0.00017 21.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_29 PF03141.16 EHU00626.1 - 0.00013 20.7 0.0 0.0002 20.1 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_32 PF13679.6 EHU00626.1 - 0.0012 18.9 0.0 0.0019 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EHU00626.1 - 0.0025 18.5 0.0 0.0085 16.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 EHU00626.1 - 0.0036 17.1 0.0 0.0099 15.6 0.0 1.7 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 EHU00626.1 - 0.046 13.8 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.13 EHU00626.1 - 0.059 12.8 0.0 0.092 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CSD PF00313.22 EHU00627.1 - 3e-33 113.5 1.6 3.2e-33 113.4 1.6 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 EHU00627.1 - 0.0012 18.5 0.4 0.0015 18.1 0.4 1.4 1 1 0 1 1 1 1 Ribonuclease B OB domain Lactamase_B_2 PF12706.7 EHU00628.1 - 2.1e-38 131.9 0.1 3.1e-38 131.3 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EHU00628.1 - 3.1e-16 59.7 0.0 3.9e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EHU00628.1 - 0.0021 18.1 0.7 0.016 15.2 0.4 2.5 2 1 0 3 3 3 1 Metallo-beta-lactamase superfamily YebO PF13974.6 EHU00629.1 - 3.1e-28 97.7 0.1 3.6e-28 97.5 0.1 1.1 1 0 0 1 1 1 1 YebO-like protein HemY_N PF07219.13 EHU00629.1 - 0.015 15.5 0.1 0.019 15.1 0.1 1.1 1 0 0 1 1 1 0 HemY protein N-terminus DivIC PF04977.15 EHU00629.1 - 0.046 13.5 0.7 0.063 13.1 0.7 1.2 1 0 0 1 1 1 0 Septum formation initiator Vpu PF00558.19 EHU00629.1 - 0.049 13.4 0.3 0.075 12.8 0.3 1.5 1 1 0 1 1 1 0 Vpu protein YobH PF13996.6 EHU00630.1 - 1e-37 128.0 0.9 1.1e-37 127.9 0.9 1.0 1 0 0 1 1 1 1 YobH-like protein IclR PF01614.18 EHU00631.1 - 1.5e-39 134.7 0.3 5.1e-38 129.8 0.0 2.4 3 0 0 3 3 2 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 EHU00631.1 - 2.8e-15 55.8 0.3 7.7e-15 54.4 0.0 1.9 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_5 PF01022.20 EHU00631.1 - 6.6e-06 25.9 0.0 1.3e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_11 PF08279.12 EHU00631.1 - 1e-05 25.3 0.0 3.8e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 HTH domain HTH_24 PF13412.6 EHU00631.1 - 3.5e-05 23.3 0.0 8.1e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 EHU00631.1 - 0.00011 22.1 0.0 0.00023 21.0 0.0 1.5 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 EHU00631.1 - 0.0002 21.2 0.0 0.00055 19.8 0.0 1.8 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 EHU00631.1 - 0.00026 20.8 0.4 0.0013 18.5 0.0 2.2 3 0 0 3 3 2 1 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.7 EHU00631.1 - 0.0013 18.8 0.2 0.0043 17.1 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain Mga PF05043.13 EHU00631.1 - 0.002 18.7 0.4 0.0058 17.2 0.1 1.9 3 0 0 3 3 1 1 Mga helix-turn-helix domain HTH_6 PF01418.17 EHU00631.1 - 0.0021 18.0 0.0 0.0044 17.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family Fe_dep_repress PF01325.19 EHU00631.1 - 0.0055 16.9 0.1 0.014 15.5 0.1 1.7 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_45 PF14947.6 EHU00631.1 - 0.0065 16.4 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_22 PF13309.6 EHU00631.1 - 0.013 15.6 0.0 0.13 12.4 0.0 2.4 2 0 0 2 2 2 0 HTH domain HTH_29 PF13551.6 EHU00631.1 - 0.013 15.5 0.0 0.03 14.3 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix HTH_27 PF13463.6 EHU00631.1 - 0.02 15.4 0.0 0.051 14.1 0.0 1.7 1 0 0 1 1 1 0 Winged helix DNA-binding domain FUR PF01475.19 EHU00631.1 - 0.02 15.0 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 Ferric uptake regulator family PadR PF03551.14 EHU00631.1 - 0.02 14.8 0.2 0.066 13.2 0.1 1.9 2 0 0 2 2 1 0 Transcriptional regulator PadR-like family Rrf2 PF02082.20 EHU00631.1 - 0.021 15.2 0.1 0.051 13.9 0.1 1.7 1 0 0 1 1 1 0 Transcriptional regulator HTH_28 PF13518.6 EHU00631.1 - 0.023 14.8 0.0 0.05 13.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 EHU00631.1 - 0.023 14.6 1.9 0.056 13.4 0.0 2.6 3 0 0 3 3 3 0 Crp-like helix-turn-helix domain HTH_7 PF02796.15 EHU00631.1 - 0.024 14.7 0.0 0.24 11.5 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Dimerisation2 PF16864.5 EHU00631.1 - 0.036 14.0 0.2 0.12 12.4 0.1 1.8 1 1 1 2 2 2 0 Dimerisation domain HTH_38 PF13936.6 EHU00631.1 - 0.071 12.9 0.0 0.22 11.3 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_DeoR PF08220.12 EHU00631.1 - 0.072 12.8 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_AsnC-type PF13404.6 EHU00631.1 - 0.081 12.8 0.0 0.24 11.3 0.0 1.9 2 0 0 2 2 1 0 AsnC-type helix-turn-helix domain HTH_26 PF13443.6 EHU00631.1 - 0.091 13.2 0.5 3.3 8.2 0.1 2.4 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain HTH_36 PF13730.6 EHU00631.1 - 0.13 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain CobS_N PF12556.8 EHU00631.1 - 0.15 11.8 0.0 0.39 10.5 0.0 1.7 1 0 0 1 1 1 0 Cobaltochelatase CobS subunit N terminal MFS_1 PF07690.16 EHU00632.1 - 6.8e-35 120.6 15.6 8e-35 120.4 15.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EHU00632.1 - 5.1e-10 38.8 7.0 5.9e-10 38.6 7.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 EHU00632.1 - 5.5e-05 22.6 12.5 7.5e-05 22.2 12.5 1.3 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 EHU00632.1 - 0.0075 14.6 1.8 0.0075 14.6 1.8 1.8 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 EHU00632.1 - 0.062 11.7 11.9 0.078 11.3 11.9 1.1 1 0 0 1 1 1 0 Transmembrane secretion effector MFS_1_like PF12832.7 EHU00632.1 - 0.13 11.1 6.8 0.16 10.8 6.8 1.2 1 0 0 1 1 1 0 MFS_1 like family DDE_Tnp_IS66 PF03050.14 EHU00633.1 - 2.8e-97 325.6 3.9 1.2e-96 323.5 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU00633.1 - 3.4e-16 59.2 0.1 1.3e-15 57.3 0.1 2.1 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU00633.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU00633.1 - 8.8e-11 42.4 9.0 1.9e-10 41.4 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Phage_HK97_TLTM PF06120.11 EHU00633.1 - 0.029 13.6 0.7 0.056 12.6 0.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein UME PF08064.13 EHU00633.1 - 0.037 13.9 0.4 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain Exonuc_VII_L PF02601.15 EHU00633.1 - 0.041 13.4 2.5 0.044 13.4 0.9 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit FUSC PF04632.12 EHU00633.1 - 0.063 11.8 7.7 0.1 11.1 7.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Csm1_N PF18504.1 EHU00633.1 - 0.13 12.7 3.4 0.86 10.0 0.2 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Tho2 PF11262.8 EHU00633.1 - 0.17 11.0 0.3 0.28 10.4 0.3 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DHR10 PF18595.1 EHU00633.1 - 0.18 11.9 10.2 0.31 11.1 10.2 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain ERM PF00769.19 EHU00633.1 - 0.27 11.0 10.4 0.45 10.3 10.4 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family LXG PF04740.12 EHU00633.1 - 0.28 10.9 2.4 0.86 9.3 0.3 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily HHH_8 PF14716.6 EHU00633.1 - 0.34 11.3 4.0 0.56 10.6 1.9 2.4 2 1 0 2 2 2 0 Helix-hairpin-helix domain Zn-ribbon_8 PF09723.10 EHU00633.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain TSNAXIP1_N PF15739.5 EHU00633.1 - 0.46 10.9 3.2 0.99 9.8 3.2 1.5 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus FAM184 PF15665.5 EHU00633.1 - 0.49 10.1 7.3 0.78 9.5 7.3 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B TMPIT PF07851.13 EHU00633.1 - 0.77 8.9 2.7 1.2 8.4 2.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein CREPT PF16566.5 EHU00633.1 - 2.3 8.4 8.3 1.1 9.5 5.2 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour HAUS-augmin3 PF14932.6 EHU00633.1 - 2.5 7.6 7.4 5.8 6.4 7.4 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 SlyX PF04102.12 EHU00633.1 - 8.5 7.1 8.7 17 6.1 2.1 3.0 1 1 1 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHU00634.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHU00635.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU00635.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU00635.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU00635.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix DDE_Tnp_IS66 PF03050.14 EHU00636.1 - 4.5e-60 203.5 5.3 1.5e-59 201.8 0.1 2.1 2 0 0 2 2 2 1 Transposase IS66 family zf-IS66 PF13005.7 EHU00636.1 - 9.3e-15 54.8 1.5 2.2e-14 53.6 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU00636.1 - 5e-11 43.2 9.0 1.1e-10 42.1 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Phage_HK97_TLTM PF06120.11 EHU00636.1 - 0.0068 15.6 0.9 0.013 14.7 0.9 1.4 1 0 0 1 1 1 1 Tail length tape measure protein Exonuc_VII_L PF02601.15 EHU00636.1 - 0.013 15.1 1.0 0.02 14.5 1.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Csm1_N PF18504.1 EHU00636.1 - 0.013 15.8 4.8 0.059 13.7 0.5 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Troponin PF00992.20 EHU00636.1 - 0.026 14.8 2.8 0.044 14.1 2.8 1.3 1 0 0 1 1 1 0 Troponin FAM184 PF15665.5 EHU00636.1 - 0.03 14.1 8.0 0.047 13.5 8.0 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Tho2 PF11262.8 EHU00636.1 - 0.031 13.5 0.6 0.047 12.9 0.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 UME PF08064.13 EHU00636.1 - 0.032 14.1 0.4 13 5.8 0.0 3.1 2 1 1 3 3 3 0 UME (NUC010) domain FUSC PF04632.12 EHU00636.1 - 0.033 12.7 7.5 0.044 12.3 7.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family LXG PF04740.12 EHU00636.1 - 0.074 12.8 3.0 0.21 11.3 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHU00636.1 - 0.096 12.5 10.8 0.14 11.9 10.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Zn-ribbon_8 PF09723.10 EHU00636.1 - 0.17 12.0 1.7 0.68 10.1 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain DHR10 PF18595.1 EHU00636.1 - 0.22 11.6 10.9 0.38 10.8 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF1192 PF06698.11 EHU00636.1 - 0.25 11.4 5.3 2.2 8.4 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) LCE6A PF15858.5 EHU00636.1 - 0.31 11.8 2.3 0.9 10.3 2.3 1.8 1 0 0 1 1 1 0 Late cornified envelope protein 6A family TMPIT PF07851.13 EHU00636.1 - 0.5 9.6 3.0 0.71 9.1 3.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein CREPT PF16566.5 EHU00636.1 - 0.81 9.8 5.6 1.5 9.0 5.6 1.4 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour HAUS-augmin3 PF14932.6 EHU00636.1 - 0.93 9.0 7.9 2 7.9 7.9 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 USP8_interact PF08941.10 EHU00636.1 - 1.1 9.0 3.5 4.2 7.1 3.5 1.9 2 1 0 2 2 2 0 USP8 interacting HalX PF08663.10 EHU00636.1 - 1.6 9.1 6.7 0.2 12.0 2.4 1.8 2 0 0 2 2 1 0 HalX domain OmpH PF03938.14 EHU00636.1 - 3.2 8.1 8.9 5.7 7.3 8.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 EHU00636.1 - 6.4 7.5 9.2 5.2 7.8 1.1 2.8 1 1 2 3 3 3 0 SlyX MerR-DNA-bind PF09278.11 EHU00636.1 - 7.8 7.1 12.3 6.6 7.4 0.4 3.3 3 0 0 3 3 3 0 MerR, DNA binding TMF_DNA_bd PF12329.8 EHU00636.1 - 8.6 6.4 8.5 6.1 6.9 0.6 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding TnpB_IS66 PF05717.13 EHU00637.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHU00638.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU00638.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU00638.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU00638.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix FMN_bind_2 PF04299.12 EHU00639.1 - 5.1e-11 42.6 0.1 5.4e-11 42.5 0.1 1.0 1 0 0 1 1 1 1 Putative FMN-binding domain GFA PF04828.14 EHU00640.1 - 2.8e-09 37.2 0.9 2.8e-09 37.2 0.9 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Cas_CXXC_CXXC PF09706.10 EHU00640.1 - 0.032 14.5 1.6 0.062 13.5 1.6 1.5 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_CXXC_CXXC) HipA_C PF07804.12 EHU00641.1 - 9.3e-17 61.4 0.0 1.2e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 HipA-like C-terminal domain Couple_hipA PF13657.6 EHU00641.1 - 1.4e-15 57.7 0.0 2.6e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 HipA N-terminal domain HTH_3 PF01381.22 EHU00642.1 - 9.9e-16 57.5 0.1 1.3e-15 57.2 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EHU00642.1 - 6.4e-12 45.7 0.1 7.7e-12 45.4 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 EHU00642.1 - 5.3e-10 39.1 0.4 6.4e-10 38.9 0.4 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 EHU00642.1 - 2.1e-08 34.1 0.0 2.6e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 EHU00642.1 - 7e-08 32.8 0.1 9.6e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 EHU00642.1 - 0.00033 20.5 0.0 0.00061 19.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.22 EHU00642.1 - 0.0014 18.5 0.2 0.0033 17.3 0.0 1.7 2 1 0 2 2 2 1 MarR family HTH_24 PF13412.6 EHU00642.1 - 0.0014 18.1 0.6 0.024 14.2 0.0 2.6 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_38 PF13936.6 EHU00642.1 - 0.011 15.4 0.2 0.069 12.9 0.0 2.1 2 1 1 3 3 3 0 Helix-turn-helix domain Pou PF00157.17 EHU00642.1 - 0.029 14.4 0.8 0.077 13.0 0.8 1.8 1 1 0 1 1 1 0 Pou domain - N-terminal to homeobox domain HTH_23 PF13384.6 EHU00642.1 - 0.08 12.8 0.1 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain Terminase_5 PF06056.12 EHU00642.1 - 0.099 12.6 0.0 0.46 10.4 0.0 2.2 1 1 1 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) HTH_IclR PF09339.10 EHU00642.1 - 0.11 12.3 0.5 0.39 10.6 0.0 2.1 2 1 0 2 2 2 0 IclR helix-turn-helix domain HTH_Crp_2 PF13545.6 EHU00642.1 - 0.12 12.4 0.5 0.52 10.3 0.1 2.1 2 1 0 2 2 2 0 Crp-like helix-turn-helix domain Acetyltransf_1 PF00583.25 EHU00643.1 - 2.2e-08 34.3 0.0 2.4e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EHU00643.1 - 2.2e-08 34.4 0.0 2.6e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EHU00643.1 - 5.1e-06 26.4 0.0 5.9e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EHU00643.1 - 0.022 14.9 0.0 0.039 14.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 EHU00643.1 - 0.13 12.3 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Glyco_hydro_3 PF00933.21 EHU00644.1 - 5e-67 226.5 0.0 7e-67 226.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EHU00644.1 - 1.9e-48 165.1 0.0 2.7e-48 164.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain MFS_2 PF13347.6 EHU00645.1 - 1.6e-108 363.0 29.1 1.8e-108 362.8 29.1 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein TMIE PF16038.5 EHU00645.1 - 6.9 6.6 6.6 31 4.5 0.5 3.7 4 0 0 4 4 4 0 TMIE protein Autoind_synth PF00765.17 EHU00646.1 - 1.8e-54 184.0 0.0 2.1e-54 183.8 0.0 1.0 1 0 0 1 1 1 1 Autoinducer synthase Autoind_bind PF03472.15 EHU00647.1 - 2e-27 95.5 0.0 2.7e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 Autoinducer binding domain GerE PF00196.19 EHU00647.1 - 3e-15 55.5 0.1 5.8e-15 54.6 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 EHU00647.1 - 2.2e-06 27.3 0.0 3.9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EHU00647.1 - 0.00033 20.1 0.0 0.00065 19.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_24 PF13412.6 EHU00647.1 - 0.00056 19.4 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 EHU00647.1 - 0.0022 18.1 0.1 0.016 15.4 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 EHU00647.1 - 0.0041 16.9 0.6 0.012 15.4 0.0 2.0 2 1 0 2 2 2 1 Homeodomain-like domain HTH_10 PF04967.12 EHU00647.1 - 0.013 15.3 0.0 0.037 13.8 0.0 1.7 1 0 0 1 1 1 0 HTH DNA binding domain HTH_5 PF01022.20 EHU00647.1 - 0.058 13.3 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family GP57 PF17594.2 EHU00647.1 - 0.069 12.9 0.4 7.8 6.3 0.0 2.3 2 0 0 2 2 2 0 Phage Tail fiber assembly helper gene product 57 adh_short_C2 PF13561.6 EHU00648.1 - 4.1e-58 196.7 0.0 4.9e-58 196.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EHU00648.1 - 2.2e-48 164.3 0.0 2.6e-48 164.1 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EHU00648.1 - 5.6e-09 36.2 0.0 7.5e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 KR domain PALP PF00291.25 EHU00648.1 - 0.044 13.2 0.1 0.063 12.7 0.1 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Beta-lactamase PF00144.24 EHU00649.1 - 3.1e-70 237.1 2.7 3.8e-70 236.7 2.7 1.0 1 0 0 1 1 1 1 Beta-lactamase Glycos_transf_1 PF00534.20 EHU00650.1 - 4.2e-10 39.4 0.0 8.7e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EHU00650.1 - 2.6e-09 37.6 0.0 5.9e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 FAD_binding_3 PF01494.19 EHU00651.1 - 7.4e-32 110.9 0.0 8.7e-32 110.7 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EHU00651.1 - 1.3e-05 24.5 0.4 2.2e-05 23.7 0.4 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EHU00651.1 - 1.6e-05 25.1 0.1 5.3e-05 23.4 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EHU00651.1 - 4.7e-05 22.7 0.7 9.9e-05 21.6 0.7 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EHU00651.1 - 5.6e-05 22.5 0.4 0.00087 18.6 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EHU00651.1 - 7e-05 21.9 2.2 0.037 12.9 0.4 2.6 2 1 1 3 3 3 2 Tryptophan halogenase Amino_oxidase PF01593.24 EHU00651.1 - 0.00069 19.0 0.1 0.85 8.8 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EHU00651.1 - 0.0026 16.5 0.4 0.013 14.2 0.4 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 EHU00651.1 - 0.0049 16.2 0.1 0.26 10.5 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EHU00651.1 - 0.1 12.2 1.2 0.19 11.3 0.4 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase SE PF08491.10 EHU00651.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase FAD_oxidored PF12831.7 EHU00651.1 - 0.12 11.7 0.9 0.2 10.9 0.9 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Peptidase_M3 PF01432.20 EHU00652.1 - 1.2e-133 446.7 1.1 1.3e-133 446.7 0.1 1.5 2 0 0 2 2 2 1 Peptidase family M3 DUF2680 PF10925.8 EHU00652.1 - 0.091 12.8 0.1 2.3 8.3 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2680) XdhC_C PF13478.6 EHU00653.1 - 6.4e-37 126.8 0.0 9.5e-37 126.3 0.0 1.3 1 0 0 1 1 1 1 XdhC Rossmann domain XdhC_CoxI PF02625.16 EHU00653.1 - 3.2e-16 59.3 0.1 6.4e-16 58.3 0.1 1.5 1 0 0 1 1 1 1 XdhC and CoxI family Ald_Xan_dh_C2 PF02738.18 EHU00654.1 - 8.2e-209 694.6 1.2 1e-208 694.3 1.2 1.0 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 EHU00654.1 - 1.7e-23 83.1 0.0 3.8e-23 81.9 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain DHHA1 PF02272.19 EHU00654.1 - 0.12 12.8 0.0 0.72 10.3 0.0 2.1 2 0 0 2 2 2 0 DHHA1 domain ACP_syn_III_C PF08541.10 EHU00654.1 - 0.14 12.3 0.1 3.2 8.0 0.0 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal FAD_binding_5 PF00941.21 EHU00655.1 - 3.8e-45 153.7 0.0 8e-45 152.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 EHU00655.1 - 1.8e-30 105.2 1.0 4.5e-30 103.8 0.5 2.0 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 EHU00655.1 - 2e-30 104.6 0.8 5e-30 103.3 0.8 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 EHU00655.1 - 0.00035 20.5 6.3 0.0025 17.7 0.6 2.9 2 0 0 2 2 2 2 2Fe-2S iron-sulfur cluster binding domain Amidohydro_1 PF01979.20 EHU00656.1 - 9e-75 252.1 0.0 1.1e-74 251.9 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EHU00656.1 - 6.6e-22 78.6 1.6 2.5e-15 56.9 0.0 2.6 2 1 1 3 3 3 2 Amidohydrolase family Peripla_BP_1 PF00532.21 EHU00656.1 - 0.12 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family adh_short PF00106.25 EHU00657.1 - 6.2e-52 175.9 0.0 7.5e-52 175.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EHU00657.1 - 2.3e-35 122.3 0.1 2.8e-35 122.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EHU00657.1 - 1.9e-12 47.5 0.0 2.6e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EHU00657.1 - 6e-09 36.0 0.2 7.2e-09 35.8 0.2 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EHU00657.1 - 2.4e-06 27.2 0.4 5.3e-06 26.1 0.2 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 EHU00657.1 - 0.00052 20.6 0.0 0.0012 19.4 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 EHU00657.1 - 0.00053 19.2 0.0 0.00092 18.4 0.0 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 EHU00657.1 - 0.0051 16.4 0.1 0.0085 15.7 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Maf_N PF08383.11 EHU00657.1 - 0.011 15.5 0.7 1.1 9.0 0.1 2.3 1 1 1 2 2 2 0 Maf N-terminal region RmlD_sub_bind PF04321.17 EHU00657.1 - 0.052 12.6 0.0 0.089 11.9 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Glyco_hydro_101 PF12905.7 EHU00657.1 - 0.069 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Endo-alpha-N-acetylgalactosaminidase TPR_7 PF13176.6 EHU00657.1 - 0.17 11.9 0.0 5.5 7.2 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat UPF0060 PF02694.15 EHU00658.1 - 3.1e-42 143.1 12.6 3.5e-42 143.0 12.6 1.0 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family DUF1283 PF06932.11 EHU00659.1 - 5.2e-44 148.4 2.1 6e-44 148.1 2.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1283) DUF1161 PF06649.12 EHU00660.1 - 3.6e-25 87.9 1.4 4.6e-25 87.6 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1161) MFS_1 PF07690.16 EHU00661.1 - 7.3e-52 176.4 55.4 7.3e-52 176.4 55.4 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EHU00661.1 - 1e-14 54.3 32.7 9.2e-11 41.3 16.0 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 EHU00661.1 - 1e-05 24.2 8.7 2.1e-05 23.2 8.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BPD_transp_1 PF00528.22 EHU00662.1 - 2.8e-24 85.9 14.7 2.8e-24 85.9 14.7 1.8 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF4229 PF14012.6 EHU00662.1 - 0.022 14.9 5.7 0.022 14.9 5.7 3.9 3 2 0 3 3 3 0 Protein of unknown function (DUF4229) FtsX PF02687.21 EHU00662.1 - 1.5 9.3 21.1 0.43 11.1 2.7 3.2 2 1 0 2 2 2 0 FtsX-like permease family OpuAC PF04069.12 EHU00663.1 - 4.5e-66 223.0 0.0 5.2e-66 222.9 0.0 1.0 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system BPD_transp_1 PF00528.22 EHU00664.1 - 4.6e-20 72.1 22.1 4.6e-20 72.1 22.1 1.4 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 EHU00665.1 - 1.8e-35 122.4 0.0 9e-35 120.2 0.0 2.0 2 0 0 2 2 2 1 ABC transporter CBS PF00571.28 EHU00665.1 - 1.7e-12 47.6 0.1 2.3e-06 27.9 0.0 2.7 2 0 0 2 2 2 2 CBS domain AAA_21 PF13304.6 EHU00665.1 - 2.9e-05 24.0 0.0 0.16 11.7 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EHU00665.1 - 8.4e-05 23.0 0.0 0.00019 21.8 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 EHU00665.1 - 0.00025 21.0 0.0 0.0005 20.0 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 EHU00665.1 - 0.00057 20.3 0.2 0.01 16.3 0.2 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EHU00665.1 - 0.0038 17.5 0.0 0.015 15.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EHU00665.1 - 0.0045 16.7 0.0 0.0092 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EHU00665.1 - 0.0049 16.8 0.1 0.0087 16.0 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_5 PF07728.14 EHU00665.1 - 0.013 15.4 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) G-alpha PF00503.20 EHU00665.1 - 0.023 13.9 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit T2SSE PF00437.20 EHU00665.1 - 0.026 13.6 0.2 0.042 12.9 0.2 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 EHU00665.1 - 0.037 13.8 0.2 0.14 11.8 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EHU00665.1 - 0.039 13.5 0.1 0.25 10.9 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EHU00665.1 - 0.044 14.1 0.1 0.15 12.4 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EHU00665.1 - 0.058 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EHU00665.1 - 0.065 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 EHU00665.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_15 PF13175.6 EHU00665.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 EHU00665.1 - 0.19 12.0 0.3 0.48 10.7 0.2 1.8 2 0 0 2 2 2 0 AAA domain AAA_26 PF13500.6 EHU00666.1 - 1.2e-26 93.8 0.0 1.4e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 EHU00666.1 - 3.4e-09 36.9 0.0 5e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1611 PF07755.11 EHU00666.1 - 0.0068 15.7 0.1 0.018 14.3 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1611_C) P-loop domain ROK PF00480.20 EHU00667.1 - 1.5e-51 175.7 0.0 1.8e-51 175.4 0.0 1.1 1 0 0 1 1 1 1 ROK family MarR_2 PF12802.7 EHU00667.1 - 1.4e-05 24.9 0.5 0.0011 18.8 0.1 2.7 2 0 0 2 2 2 1 MarR family MarR PF01047.22 EHU00667.1 - 0.00011 22.1 0.3 0.00064 19.6 0.0 2.2 2 0 0 2 2 2 1 MarR family Fe_dep_repress PF01325.19 EHU00667.1 - 0.00055 20.1 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_24 PF13412.6 EHU00667.1 - 0.074 12.6 0.0 0.21 11.2 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding LysR_substrate PF03466.20 EHU00668.1 - 2.1e-45 154.7 3.0 2.1e-45 154.7 3.0 1.7 1 1 1 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 EHU00668.1 - 1.1e-23 83.0 0.5 2.1e-23 82.0 0.5 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MFS_1 PF07690.16 EHU00669.1 - 1.9e-33 115.8 65.3 8e-25 87.5 30.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EHU00669.1 - 9.7e-07 28.0 18.1 9.7e-07 28.0 18.1 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 EHU00669.1 - 0.00069 18.6 15.5 0.0021 17.0 6.2 3.1 2 1 1 3 3 3 2 MFS_1 like family DUF2614 PF11023.8 EHU00669.1 - 2.2 8.4 6.0 12 6.0 0.4 2.8 2 0 0 2 2 2 0 Zinc-ribbon containing domain Ni_hydr_CYTB PF01292.20 EHU00671.1 - 1.3e-21 77.0 12.7 1.7e-21 76.7 12.7 1.1 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 MFS_1 PF07690.16 EHU00672.1 - 9.2e-30 103.7 59.0 9.2e-30 103.7 59.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EHU00672.1 - 0.0022 17.3 36.1 0.0022 17.3 36.1 1.3 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB zf-dskA_traR PF01258.17 EHU00674.1 - 1.1e-13 50.9 4.5 1.6e-13 50.3 4.5 1.3 1 0 0 1 1 1 1 Prokaryotic dksA/traR C4-type zinc finger DZR PF12773.7 EHU00674.1 - 0.0035 17.3 1.2 0.0051 16.8 1.2 1.2 1 0 0 1 1 1 1 Double zinc ribbon C1_1 PF00130.22 EHU00674.1 - 0.0078 16.1 0.4 0.02 14.8 0.3 1.6 1 1 1 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Auto_anti-p27 PF06677.12 EHU00674.1 - 0.014 15.5 0.8 0.024 14.8 0.8 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF4428 PF14471.6 EHU00674.1 - 0.028 14.3 0.3 0.042 13.8 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) AAA_13 PF13166.6 EHU00674.1 - 0.042 12.5 0.2 0.042 12.5 0.2 1.2 1 0 0 1 1 1 0 AAA domain zinc_ribbon_2 PF13240.6 EHU00674.1 - 0.49 10.2 3.2 9.8 6.0 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain COesterase PF00135.28 EHU00675.1 - 1.4e-93 314.5 0.0 2e-91 307.4 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EHU00675.1 - 3.3e-08 33.6 1.3 0.00088 19.2 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EHU00675.1 - 0.046 12.6 0.0 1.9 7.3 0.0 2.1 2 0 0 2 2 2 0 Steryl acetyl hydrolase DoxX PF07681.12 EHU00676.1 - 3.9e-15 56.2 10.9 3.9e-15 56.2 10.9 1.7 2 0 0 2 2 2 1 DoxX DoxD PF04173.13 EHU00676.1 - 0.012 15.5 3.7 0.012 15.5 3.2 1.3 1 1 0 1 1 1 0 TQO small subunit DoxD DUF1338 PF07063.13 EHU00677.1 - 6.9e-115 383.7 0.1 8e-115 383.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) MFS_1 PF07690.16 EHU00678.1 - 2.7e-47 161.4 62.5 7.4e-34 117.2 29.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EHU00678.1 - 1.8e-30 106.2 30.7 1.7e-26 93.1 7.0 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 EHU00678.1 - 4e-10 39.5 34.8 4.1e-10 39.5 9.9 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB PUCC PF03209.15 EHU00678.1 - 2.9e-05 23.3 1.8 2.9e-05 23.3 1.8 3.4 2 2 1 3 3 3 1 PUCC protein MFS_1_like PF12832.7 EHU00678.1 - 0.00032 19.7 16.6 0.032 13.1 0.1 2.4 2 1 0 2 2 2 2 MFS_1 like family OATP PF03137.20 EHU00678.1 - 3.5 5.8 19.2 0.86 7.8 3.1 3.0 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family LysR_substrate PF03466.20 EHU00679.1 - 1.9e-34 118.9 0.5 3.4e-34 118.1 0.5 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EHU00679.1 - 5.7e-19 67.8 3.0 1.8e-18 66.2 3.0 1.9 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_20 PF12840.7 EHU00679.1 - 0.0087 16.1 0.4 0.034 14.2 0.4 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain DiSB-ORF2_chro PF16506.5 EHU00679.1 - 0.03 14.3 0.1 0.054 13.5 0.1 1.3 1 0 0 1 1 1 0 Putative virion glycoprotein of insect viruses HTH_30 PF13556.6 EHU00679.1 - 0.033 14.0 0.2 0.068 13.0 0.2 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain G_glu_transpept PF01019.21 EHU00679.1 - 0.1 11.4 0.0 0.35 9.6 0.0 1.7 2 0 0 2 2 2 0 Gamma-glutamyltranspeptidase Smr PF01713.21 EHU00680.1 - 5.6e-17 61.9 0.0 8.2e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 Smr domain cNMP_binding PF00027.29 EHU00681.1 - 3.7e-17 62.2 0.0 7.7e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 EHU00681.1 - 5.1e-16 58.4 0.1 8.5e-16 57.7 0.1 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Crp PF00325.20 EHU00681.1 - 6.2e-16 57.8 0.5 1e-15 57.1 0.5 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, crp family MarR_2 PF12802.7 EHU00681.1 - 0.023 14.5 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 MarR family Med1 PF10744.9 EHU00681.1 - 0.19 10.8 0.0 0.23 10.4 0.0 1.1 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription subunit 1 Usp PF00582.26 EHU00682.1 - 7e-33 114.1 0.1 1.4e-18 67.8 0.0 2.2 2 0 0 2 2 2 2 Universal stress protein family Malectin_like PF12819.7 EHU00682.1 - 0.22 10.6 0.0 0.3 10.2 0.0 1.1 1 0 0 1 1 1 0 Malectin-like domain PNTB PF02233.16 EHU00683.1 - 4.6e-203 675.3 16.9 5.2e-203 675.1 16.9 1.0 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit TraA PF05513.11 EHU00683.1 - 0.0023 18.3 1.1 0.0069 16.7 1.1 1.9 1 0 0 1 1 1 1 TraA TPP_enzyme_M PF00205.22 EHU00683.1 - 0.021 14.6 0.8 0.13 12.0 0.1 2.6 2 1 1 3 3 3 0 Thiamine pyrophosphate enzyme, central domain DUF4229 PF14012.6 EHU00683.1 - 0.57 10.3 0.1 0.57 10.3 0.1 5.3 4 1 2 6 6 6 0 Protein of unknown function (DUF4229) AlaDh_PNT_C PF01262.21 EHU00684.1 - 1e-74 250.4 1.9 1.7e-74 249.7 1.9 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 EHU00684.1 - 3.2e-51 173.2 0.0 6.2e-51 172.3 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 EHU00684.1 - 2.1e-36 124.2 8.3 6.6e-36 122.6 8.3 1.9 1 0 0 1 1 1 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 EHU00684.1 - 0.00038 19.9 0.5 0.12 11.7 0.1 2.8 2 1 1 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 EHU00684.1 - 0.015 14.6 0.3 0.025 13.8 0.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF3392 PF11872.8 EHU00684.1 - 0.099 12.9 2.2 0.25 11.6 2.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3392) NAD_binding_8 PF13450.6 EHU00684.1 - 0.48 10.7 2.2 3 8.2 1.6 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF1471 PF07338.13 EHU00685.1 - 4.6e-64 212.3 0.6 5.8e-21 74.2 0.0 3.5 3 0 0 3 3 3 3 Protein of unknown function (DUF1471) AA_permease_2 PF13520.6 EHU00686.1 - 1.8e-70 237.9 44.8 2.8e-70 237.3 44.8 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EHU00686.1 - 2.4e-14 52.8 41.9 5.3e-14 51.7 41.7 1.5 1 1 0 1 1 1 1 Amino acid permease Trans_reg_C PF00486.28 EHU00688.1 - 1.3e-21 76.4 0.2 3.6e-21 75.0 0.0 1.7 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 EHU00688.1 - 5.8e-20 71.5 0.0 8.4e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 EHU00689.1 - 2.2e-19 70.0 0.0 4.1e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EHU00689.1 - 5.7e-07 29.5 1.1 5.7e-07 29.5 1.1 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 EHU00689.1 - 1.2e-05 25.5 0.0 3.9e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 HAMP domain HATPase_c_3 PF13589.6 EHU00689.1 - 0.0018 18.1 0.0 0.0034 17.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EHU00689.1 - 0.032 14.2 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Peptidase_M32 PF02074.15 EHU00690.1 - 1.9e-172 574.5 0.0 2.1e-172 574.3 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase Asr PF06392.11 EHU00691.1 - 0.054 13.9 10.1 0.054 13.9 10.1 9.4 3 3 5 8 8 8 0 Acid shock protein repeat Hid1 PF12722.7 EHU00691.1 - 10 4.1 21.7 11 4.0 21.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Trypsin PF00089.26 EHU00692.1 - 8.2e-10 38.9 0.0 3.2e-09 36.9 0.0 1.9 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 EHU00692.1 - 3.9e-06 27.8 0.0 5.8e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF3418 PF11898.8 EHU00693.1 - 3.7e-237 788.7 3.5 3.7e-237 788.7 3.5 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3418) OB_NTP_bind PF07717.16 EHU00693.1 - 4.4e-18 65.4 0.0 8.2e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EHU00693.1 - 1.2e-17 64.1 0.0 3.4e-17 62.7 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EHU00693.1 - 7.9e-12 45.5 0.0 2.5e-11 43.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EHU00693.1 - 5.4e-08 32.8 0.1 1.5e-07 31.4 0.1 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EHU00693.1 - 3.3e-05 24.2 0.1 0.00011 22.6 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EHU00693.1 - 0.0002 21.2 0.2 0.00042 20.1 0.2 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EHU00693.1 - 0.00022 20.4 0.0 0.00054 19.1 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 EHU00693.1 - 0.00046 20.5 0.6 0.0029 17.9 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EHU00693.1 - 0.00071 20.1 0.0 0.0016 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EHU00693.1 - 0.002 17.6 0.1 0.0045 16.5 0.1 1.5 1 0 0 1 1 1 1 PhoH-like protein NACHT PF05729.12 EHU00693.1 - 0.0047 16.8 2.3 0.042 13.8 1.1 2.9 2 1 0 2 2 2 1 NACHT domain DUF2075 PF09848.9 EHU00693.1 - 0.0093 15.2 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 EHU00693.1 - 0.059 12.9 1.4 0.18 11.4 0.1 2.5 3 1 0 3 3 3 0 AAA domain ResIII PF04851.15 EHU00693.1 - 0.37 10.8 2.1 3 7.8 0.7 2.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Flavodoxin_2 PF02525.17 EHU00694.1 - 2.1e-46 158.2 0.0 2.4e-46 158.0 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 EHU00694.1 - 2.2e-13 50.2 0.0 2.8e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_5 PF12724.7 EHU00694.1 - 0.084 13.1 0.0 8.6 6.6 0.0 2.2 2 0 0 2 2 2 0 Flavodoxin domain DUF1318 PF07027.12 EHU00695.1 - 1.2e-27 96.1 0.6 1.4e-27 95.9 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1318) PG_binding_3 PF09374.10 EHU00695.1 - 0.0095 16.2 0.1 0.011 15.9 0.1 1.2 1 0 0 1 1 1 1 Predicted Peptidoglycan domain Lipoprotein_19 PF13617.6 EHU00696.1 - 1.6e-17 63.0 5.6 1.9e-17 62.7 5.6 1.1 1 0 0 1 1 1 1 YnbE-like lipoprotein DctA-YdbH PF11739.8 EHU00697.1 - 3.8e-65 219.5 1.6 1.2e-64 217.8 0.0 2.8 3 0 0 3 3 3 1 Dicarboxylate transport DUF748 PF05359.11 EHU00697.1 - 0.0016 18.6 0.2 0.056 13.6 0.0 3.4 4 0 0 4 4 4 1 Domain of Unknown Function (DUF748) NPR2 PF06218.11 EHU00697.1 - 0.035 12.9 0.1 0.051 12.3 0.1 1.1 1 0 0 1 1 1 0 Nitrogen permease regulator 2 2-Hacid_dh_C PF02826.19 EHU00698.1 - 2.9e-53 179.9 0.0 4.5e-53 179.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EHU00698.1 - 1.3e-33 115.5 0.0 1.4e-33 115.4 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 EHU00698.1 - 0.0027 17.8 0.0 0.0051 16.9 0.0 1.4 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain CoA_binding_2 PF13380.6 EHU00698.1 - 0.0064 17.0 0.0 0.022 15.3 0.0 1.9 1 1 0 1 1 1 1 CoA binding domain NAD_binding_2 PF03446.15 EHU00698.1 - 0.0075 16.4 0.0 0.031 14.5 0.0 1.9 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.6 EHU00698.1 - 0.047 14.2 0.0 0.14 12.6 0.0 1.8 1 0 0 1 1 1 0 XdhC Rossmann domain DUF333 PF03891.15 EHU00699.1 - 1.6e-13 50.6 0.4 2.1e-13 50.2 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF333) LPAM_1 PF08139.12 EHU00699.1 - 0.011 16.2 4.2 0.024 15.1 4.2 1.7 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Lir1 PF07207.11 EHU00699.1 - 0.074 13.3 0.8 0.086 13.1 0.8 1.0 1 0 0 1 1 1 0 Light regulated protein Lir1 MgtC PF02308.16 EHU00700.1 - 3.8e-40 137.0 11.9 5.2e-40 136.6 11.9 1.2 1 0 0 1 1 1 1 MgtC family ATP_bind_3 PF01171.20 EHU00701.1 - 2.1e-11 43.9 0.0 4.5e-11 42.8 0.0 1.5 1 1 0 1 1 1 1 PP-loop family HTH_Tnp_1 PF01527.20 EHU00702.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU00702.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU00702.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU00702.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHU00703.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHU00704.1 - 3.3e-30 105.5 2.0 9.7e-29 100.7 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family zf-IS66 PF13005.7 EHU00704.1 - 7.7e-15 55.0 1.5 1.8e-14 53.8 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU00704.1 - 5.9e-12 46.2 9.0 1.2e-11 45.2 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHU00704.1 - 0.0073 16.1 6.2 0.011 15.6 6.2 1.1 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B Csm1_N PF18504.1 EHU00704.1 - 0.0083 16.4 4.6 0.046 14.1 0.4 2.5 1 1 1 2 2 2 1 Csm1 N-terminal domain Exonuc_VII_L PF02601.15 EHU00704.1 - 0.013 15.1 0.6 0.015 14.9 0.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phage_HK97_TLTM PF06120.11 EHU00704.1 - 0.013 14.7 1.7 0.021 14.0 1.7 1.2 1 0 0 1 1 1 0 Tail length tape measure protein FUSC PF04632.12 EHU00704.1 - 0.021 13.4 6.8 0.027 13.0 6.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Troponin PF00992.20 EHU00704.1 - 0.03 14.6 3.1 0.05 13.9 3.1 1.3 1 0 0 1 1 1 0 Troponin LXG PF04740.12 EHU00704.1 - 0.04 13.6 2.7 0.18 11.5 0.5 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily Tho2 PF11262.8 EHU00704.1 - 0.073 12.3 1.8 0.1 11.8 1.8 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 ERM PF00769.19 EHU00704.1 - 0.083 12.7 10.8 0.12 12.2 10.8 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Zn-ribbon_8 PF09723.10 EHU00704.1 - 0.14 12.3 1.7 0.58 10.3 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain DUF1192 PF06698.11 EHU00704.1 - 0.19 11.8 5.3 1.9 8.6 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DHR10 PF18595.1 EHU00704.1 - 0.19 11.8 10.9 0.3 11.1 10.9 1.2 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain RD3 PF14473.6 EHU00704.1 - 0.24 11.2 2.2 0.46 10.3 2.2 1.4 1 0 0 1 1 1 0 RD3 protein TMPIT PF07851.13 EHU00704.1 - 0.57 9.4 3.1 0.81 8.9 3.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein PCRF PF03462.18 EHU00704.1 - 0.65 9.8 3.8 1 9.2 3.8 1.2 1 0 0 1 1 1 0 PCRF domain USP8_interact PF08941.10 EHU00704.1 - 0.84 9.4 3.5 4.2 7.1 3.7 2.0 2 1 0 2 2 2 0 USP8 interacting HAUS-augmin3 PF14932.6 EHU00704.1 - 1.2 8.7 7.8 2.5 7.6 7.8 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 LCE6A PF15858.5 EHU00704.1 - 1.5 9.6 4.9 1.2 9.9 3.0 1.8 2 0 0 2 2 1 0 Late cornified envelope protein 6A family OmpH PF03938.14 EHU00704.1 - 2.2 8.6 8.0 3.3 8.1 8.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HalX PF08663.10 EHU00704.1 - 3.3 8.1 8.1 0.29 11.5 3.1 1.8 2 0 0 2 2 1 0 HalX domain SlyX PF04102.12 EHU00704.1 - 4.8 7.9 9.3 7.7 7.2 2.1 2.7 1 1 1 2 2 2 0 SlyX MerR-DNA-bind PF09278.11 EHU00704.1 - 6 7.5 10.0 5.7 7.6 0.5 2.5 2 0 0 2 2 2 0 MerR, DNA binding TMF_DNA_bd PF12329.8 EHU00704.1 - 6.5 6.8 8.5 5.2 7.2 0.6 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DDE_Tnp_IS66 PF03050.14 EHU00705.1 - 7e-41 140.5 0.1 8.1e-41 140.3 0.1 1.0 1 0 0 1 1 1 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU00705.1 - 1.3e-16 60.5 0.1 2.9e-16 59.4 0.1 1.6 1 0 0 1 1 1 1 IS66 C-terminal element WGG PF10273.9 EHU00705.1 - 0.11 13.1 0.1 0.33 11.6 0.1 1.8 2 0 0 2 2 2 0 Pre-rRNA-processing protein TSR2 CorA PF01544.18 EHU00706.1 - 9.5e-63 212.2 0.0 1.1e-62 212.0 0.0 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DDE_3 PF13358.6 EHU00707.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHU00707.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHU00707.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHU00707.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHU00707.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHU00707.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHU00707.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHU00707.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 SBP_bac_5 PF00496.22 EHU00708.1 - 1.9e-87 293.7 7.5 2.8e-87 293.1 7.5 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle SBP_bac_3 PF00497.20 EHU00708.1 - 0.022 14.2 0.4 0.12 11.7 0.0 2.3 3 0 0 3 3 3 0 Bacterial extracellular solute-binding proteins, family 3 Peptidase_M14 PF00246.24 EHU00709.1 - 7e-14 52.3 0.1 2.4e-13 50.6 0.1 1.7 1 1 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 EHU00709.1 - 1.4e-06 27.6 0.2 1.8e-06 27.3 0.2 1.2 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.8 EHU00709.1 - 1.7e-05 24.4 0.1 2.3e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) MR_MLE_C PF13378.6 EHU00710.1 - 3.9e-26 92.0 2.0 5.8e-26 91.4 2.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EHU00710.1 - 3.2e-23 82.2 0.0 5.9e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 EHU00710.1 - 0.077 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Ezh2_MCSS PF18600.1 EHU00710.1 - 0.87 9.3 3.7 5.2 6.8 0.3 2.5 2 1 0 2 2 2 0 MCSS domain Redoxin PF08534.10 EHU00711.1 - 1.4e-28 99.4 0.0 1.7e-28 99.2 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EHU00711.1 - 2.3e-15 56.6 0.0 2.7e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Sigma54_activat PF00158.26 EHU00712.1 - 5.7e-61 205.1 0.0 8.8e-61 204.5 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain HTH_50 PF18024.1 EHU00712.1 - 3.7e-19 68.1 0.4 7.5e-19 67.1 0.4 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma54_activ_2 PF14532.6 EHU00712.1 - 1e-18 67.8 0.0 3.3e-18 66.1 0.0 1.9 1 0 0 1 1 1 1 Sigma-54 interaction domain ACT PF01842.25 EHU00712.1 - 1.6e-06 27.7 0.0 3.6e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 ACT domain AAA_5 PF07728.14 EHU00712.1 - 4.1e-05 23.6 0.0 0.00013 22.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ACT_4 PF13291.6 EHU00712.1 - 0.00012 22.6 0.0 0.00027 21.4 0.0 1.7 1 0 0 1 1 1 1 ACT domain AAA PF00004.29 EHU00712.1 - 0.00029 21.3 0.0 0.00089 19.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PAS_8 PF13188.7 EHU00712.1 - 0.00077 19.4 0.1 0.0028 17.6 0.1 2.0 1 0 0 1 1 1 1 PAS domain HTH_Tnp_ISL3 PF13542.6 EHU00712.1 - 0.0036 16.7 0.0 0.0078 15.6 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 PAS PF00989.25 EHU00712.1 - 0.0041 17.1 0.0 0.026 14.5 0.0 2.3 2 0 0 2 2 2 1 PAS fold AAA_7 PF12775.7 EHU00712.1 - 0.0052 16.3 0.0 0.0091 15.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region PAS_4 PF08448.10 EHU00712.1 - 0.0077 16.5 0.4 0.44 10.8 0.1 2.9 1 1 1 2 2 2 1 PAS fold AAA_2 PF07724.14 EHU00712.1 - 0.034 14.2 0.0 0.091 12.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 EHU00712.1 - 0.056 12.8 0.1 3.7 6.9 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 EHU00712.1 - 0.11 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) HTH_10 PF04967.12 EHU00712.1 - 0.13 12.1 0.0 0.47 10.3 0.0 2.0 1 0 0 1 1 1 0 HTH DNA binding domain NUMOD1 PF07453.13 EHU00712.1 - 0.25 11.7 0.1 0.83 10.0 0.1 1.9 2 0 0 2 2 2 0 NUMOD1 domain DUF697 PF05128.12 EHU00713.1 - 1.1e-53 181.3 1.8 7.8e-53 178.5 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF697) EcsC PF12787.7 EHU00713.1 - 0.0043 16.8 0.3 0.024 14.3 0.1 2.1 2 0 0 2 2 2 1 EcsC protein family DUF463 PF04317.12 EHU00714.1 - 1.3e-186 620.9 0.1 1.5e-186 620.7 0.1 1.0 1 0 0 1 1 1 1 YcjX-like family, DUF463 AAA_22 PF13401.6 EHU00714.1 - 0.072 13.4 0.0 2.5 8.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain Pox_A32 PF04665.12 EHU00714.1 - 0.081 12.4 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein Phageshock_PspD PF09584.10 EHU00715.1 - 1.6e-29 101.7 2.8 1.9e-29 101.5 2.8 1.1 1 0 0 1 1 1 1 Phage shock protein PspD (Phageshock_PspD) GtrA PF04138.14 EHU00715.1 - 0.1 12.9 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 GtrA-like protein PspC PF04024.12 EHU00716.1 - 3.1e-15 55.7 1.6 4.3e-15 55.3 1.6 1.2 1 0 0 1 1 1 1 PspC domain PSD1 PF07587.11 EHU00716.1 - 0.005 16.4 0.0 0.0061 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1553) PspB PF06667.12 EHU00717.1 - 1.5e-32 111.5 0.3 1.6e-32 111.3 0.3 1.0 1 0 0 1 1 1 1 Phage shock protein B BatA PF07584.11 EHU00717.1 - 0.00032 21.0 0.3 0.00037 20.8 0.3 1.1 1 0 0 1 1 1 1 Aerotolerance regulator N-terminal KxDL PF10241.9 EHU00717.1 - 0.036 14.3 0.0 0.041 14.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein AIP3 PF03915.13 EHU00717.1 - 0.038 13.1 0.1 0.043 12.9 0.1 1.0 1 0 0 1 1 1 0 Actin interacting protein 3 Ac76 PF05814.11 EHU00717.1 - 0.046 13.7 0.0 0.074 13.1 0.0 1.4 1 1 0 1 1 1 0 Orf76 (Ac76) PspA_IM30 PF04012.12 EHU00718.1 - 2.2e-48 164.8 28.9 2.4e-48 164.6 28.9 1.0 1 0 0 1 1 1 1 PspA/IM30 family Filo_VP35 PF02097.15 EHU00718.1 - 0.022 13.8 0.5 0.031 13.4 0.5 1.3 1 0 0 1 1 1 0 Filoviridae VP35 MPS2 PF17060.5 EHU00718.1 - 0.18 11.1 11.5 0.18 11.0 10.9 1.3 1 1 0 1 1 1 0 Monopolar spindle protein 2 Spc7 PF08317.11 EHU00718.1 - 0.36 9.7 24.1 0.28 10.0 21.4 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.12 EHU00718.1 - 0.45 10.6 15.5 0.093 12.8 2.3 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) SHE3 PF17078.5 EHU00718.1 - 0.82 9.3 21.3 3.4 7.3 9.4 3.0 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 DUF489 PF04356.12 EHU00718.1 - 0.91 9.5 8.5 0.16 12.0 1.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF489) FAM76 PF16046.5 EHU00718.1 - 1.9 7.8 16.0 0.52 9.6 12.0 2.0 1 1 1 2 2 2 0 FAM76 protein DUF5082 PF16888.5 EHU00718.1 - 2.4 8.4 17.3 0.12 12.7 9.5 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF5082) ABC_tran_CTD PF16326.5 EHU00718.1 - 2.5 8.4 27.8 0.82 10.0 6.1 4.3 1 1 2 3 3 3 0 ABC transporter C-terminal domain Baculo_PEP_C PF04513.12 EHU00718.1 - 4.5 7.3 7.8 1.6 8.7 1.1 2.7 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.11 EHU00718.1 - 5.6 7.4 10.3 6.2 7.3 0.6 4.3 3 2 2 5 5 5 0 Flagella accessory protein C (FlaC) Fzo_mitofusin PF04799.13 EHU00718.1 - 7.1 6.2 14.4 0.065 12.8 3.4 2.7 1 1 2 3 3 3 0 fzo-like conserved region ERM PF00769.19 EHU00718.1 - 7.7 6.2 31.0 15 5.3 31.0 1.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family ZapB PF06005.12 EHU00718.1 - 8 7.0 25.6 0.12 12.9 6.3 3.5 3 1 0 3 3 3 0 Cell division protein ZapB YabA PF06156.13 EHU00718.1 - 8.3 7.1 16.8 0.5 11.0 2.6 3.1 2 1 0 3 3 3 0 Initiation control protein YabA Prominin PF05478.11 EHU00718.1 - 8.4 4.2 9.6 2.1 6.2 5.4 1.6 1 1 0 1 1 1 0 Prominin FapA PF03961.13 EHU00718.1 - 9.9 4.6 15.2 3.7 6.1 10.8 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A Sigma54_activat PF00158.26 EHU00719.1 - 6e-60 201.8 0.0 8.5e-60 201.3 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EHU00719.1 - 7.7e-21 74.7 0.0 2.4e-20 73.1 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 EHU00719.1 - 4e-07 30.1 0.0 6.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EHU00719.1 - 2.1e-06 27.3 0.0 0.002 17.5 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI HTH_8 PF02954.19 EHU00719.1 - 3.9e-05 23.3 0.2 0.00014 21.6 0.2 2.0 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family AAA_2 PF07724.14 EHU00719.1 - 0.0018 18.4 0.0 0.003 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 EHU00719.1 - 0.0067 16.9 0.0 0.017 15.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EHU00719.1 - 0.007 16.8 0.6 0.016 15.6 0.1 1.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 EHU00719.1 - 0.026 14.0 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region HTH_23 PF13384.6 EHU00719.1 - 0.14 12.0 0.1 0.41 10.5 0.1 1.8 1 0 0 1 1 1 0 Homeodomain-like domain ATPase PF06745.13 EHU00719.1 - 0.17 11.2 0.0 0.78 9.0 0.0 2.0 3 0 0 3 3 3 0 KaiC SBP_bac_5 PF00496.22 EHU00720.1 - 5.2e-89 298.8 0.1 6.4e-89 298.5 0.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Ribosomal_L5 PF00281.19 EHU00720.1 - 0.12 12.7 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L5 HTH_ABP1_N PF18107.1 EHU00720.1 - 0.21 11.3 0.6 0.47 10.2 0.1 1.8 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain BPD_transp_1 PF00528.22 EHU00721.1 - 2.8e-42 144.6 12.6 2.8e-42 144.6 12.6 2.1 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 EHU00722.1 - 4.2e-22 78.8 10.0 4.2e-22 78.8 10.0 1.6 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 EHU00722.1 - 7.4e-10 38.7 3.8 5.2e-09 35.9 0.1 2.7 2 0 0 2 2 2 1 N-terminal TM domain of oligopeptide transport permease C Cyd_oper_YbgE PF09600.10 EHU00722.1 - 0.005 17.2 2.2 0.016 15.5 2.2 1.9 1 0 0 1 1 1 1 Cyd operon protein YbgE (Cyd_oper_YbgE) ABC_tran PF00005.27 EHU00723.1 - 5.8e-29 101.4 0.0 5.1e-27 95.1 0.0 2.0 2 0 0 2 2 2 1 ABC transporter oligo_HPY PF08352.12 EHU00723.1 - 2.8e-17 63.0 0.2 7.1e-17 61.7 0.2 1.7 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 EHU00723.1 - 2.6e-08 34.0 0.0 3.2e-06 27.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EHU00723.1 - 0.0012 19.1 1.9 1.3 9.3 0.1 2.3 2 1 0 2 2 2 2 AAA domain SMC_N PF02463.19 EHU00723.1 - 0.021 14.3 0.1 0.12 11.8 0.1 1.9 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA PF00004.29 EHU00723.1 - 0.035 14.5 0.1 0.68 10.4 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EHU00723.1 - 0.053 13.5 0.1 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EHU00723.1 - 0.1 12.3 0.0 12 5.6 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 EHU00723.1 - 0.18 11.5 0.1 0.84 9.3 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 EHU00724.1 - 8.3e-32 110.6 0.0 1.3e-31 110.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 EHU00724.1 - 2.2e-06 28.0 0.1 6.7e-06 26.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 EHU00724.1 - 5e-05 22.8 0.9 0.00082 18.9 0.9 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EHU00724.1 - 0.00032 20.6 0.2 0.00063 19.7 0.0 1.5 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EHU00724.1 - 0.00069 19.3 0.1 0.0013 18.4 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 EHU00724.1 - 0.00078 19.2 0.1 0.0099 15.6 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_15 PF13175.6 EHU00724.1 - 0.00081 19.2 0.0 0.00081 19.2 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EHU00724.1 - 0.0036 17.8 0.0 0.0053 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF87 PF01935.17 EHU00724.1 - 0.0051 16.9 0.0 0.008 16.3 0.0 1.3 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_24 PF13479.6 EHU00724.1 - 0.011 15.5 0.2 0.03 14.1 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 EHU00724.1 - 0.011 15.5 0.4 0.025 14.4 0.2 1.6 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 EHU00724.1 - 0.013 15.9 0.0 0.035 14.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 EHU00724.1 - 0.013 15.9 0.1 0.02 15.3 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 EHU00724.1 - 0.017 15.1 0.1 0.04 13.8 0.1 1.6 1 0 0 1 1 1 0 NACHT domain TrwB_AAD_bind PF10412.9 EHU00724.1 - 0.027 13.4 0.1 0.052 12.5 0.0 1.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ABC_ATPase PF09818.9 EHU00724.1 - 0.032 13.0 0.6 1.1 8.0 0.1 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Sigma54_activat PF00158.26 EHU00724.1 - 0.042 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF3652 PF12372.8 EHU00724.1 - 0.042 13.7 0.1 0.081 12.8 0.1 1.4 1 0 0 1 1 1 0 Huntingtin protein region AAA_10 PF12846.7 EHU00724.1 - 0.059 12.3 0.0 0.096 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA PF00004.29 EHU00724.1 - 0.06 13.8 0.0 1 9.8 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 EHU00724.1 - 0.063 13.4 0.1 0.26 11.4 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 EHU00724.1 - 0.074 13.2 0.0 0.16 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EHU00724.1 - 0.084 12.0 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Mg_chelatase PF01078.21 EHU00724.1 - 0.084 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EHU00724.1 - 0.095 12.9 0.0 1.6 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 EHU00724.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_13 PF13166.6 EHU00724.1 - 0.17 10.5 0.1 0.48 9.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain oligo_HPY PF08352.12 EHU00724.1 - 0.19 12.2 0.0 0.37 11.3 0.0 1.4 1 0 0 1 1 1 0 Oligopeptide/dipeptide transporter, C-terminal region adh_short_C2 PF13561.6 EHU00725.1 - 2.1e-86 289.3 0.2 2.3e-86 289.1 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EHU00725.1 - 4.7e-15 55.6 0.0 5.8e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EHU00725.1 - 0.0065 16.4 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 KR domain LysR_substrate PF03466.20 EHU00727.1 - 2.3e-23 82.7 7.8 2.7e-23 82.4 7.8 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EHU00727.1 - 0.018 15.0 0.0 0.041 13.8 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family PTS_EIIC PF02378.18 EHU00729.1 - 2.4e-75 253.5 35.5 2.4e-75 253.5 35.5 1.4 2 0 0 2 2 2 1 Phosphotransferase system, EIIC PTS_EIIB PF00367.20 EHU00729.1 - 1.9e-11 43.2 0.2 3.4e-11 42.4 0.2 1.4 1 0 0 1 1 1 1 phosphotransferase system, EIIB DUF2563 PF10817.8 EHU00729.1 - 0.21 12.2 3.3 5 7.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2563) Molybdopterin PF00384.22 EHU00730.1 - 5.2e-23 81.7 0.0 5e-22 78.5 0.0 2.0 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 EHU00730.1 - 8.1e-12 45.2 0.0 1.5e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain DUF3539 PF12058.8 EHU00730.1 - 0.062 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3539) CDC48_N PF02359.18 EHU00730.1 - 0.08 13.1 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain RNB PF00773.19 EHU00731.1 - 1.1e-86 291.1 0.0 1.4e-86 290.8 0.0 1.1 1 0 0 1 1 1 1 RNB domain OB_RNB PF08206.11 EHU00731.1 - 1e-19 70.0 0.4 2.4e-19 68.8 0.1 1.9 2 0 0 2 2 2 1 Ribonuclease B OB domain S1 PF00575.23 EHU00731.1 - 3.5e-11 43.3 1.8 3.9e-09 36.7 0.4 2.5 2 0 0 2 2 2 2 S1 RNA binding domain CSD2 PF17876.1 EHU00731.1 - 1.4e-10 41.2 0.0 1e-07 32.0 0.0 2.9 3 0 0 3 3 3 2 Cold shock domain PilZ PF07238.14 EHU00731.1 - 0.01 16.1 0.0 0.028 14.7 0.0 1.7 1 0 0 1 1 1 0 PilZ domain CstA PF02554.14 EHU00732.1 - 2e-170 566.7 25.6 2e-170 566.7 25.6 2.3 3 1 0 3 3 3 1 Carbon starvation protein CstA CstA_5TM PF13722.6 EHU00732.1 - 9.4e-33 113.0 8.6 9.4e-33 113.0 8.6 3.7 4 0 0 4 4 4 1 5TM C-terminal transporter carbon starvation CstA DUF2417 PF10329.9 EHU00732.1 - 0.012 15.0 1.7 0.012 15.0 1.7 2.5 2 0 0 2 2 2 0 Region of unknown function (DUF2417) DUF3278 PF11683.8 EHU00732.1 - 6.4 6.9 14.1 9.8 6.3 0.1 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3278) Sel_put PF04328.13 EHU00733.1 - 1.2e-24 86.1 1.1 1.7e-24 85.6 1.1 1.2 1 0 0 1 1 1 1 Selenoprotein, putative Nup54_57_C PF18570.1 EHU00733.1 - 3.3 7.4 4.9 5 6.8 4.9 1.2 1 0 0 1 1 1 0 NUP57/Nup54 C-terminal domain EAL PF00563.20 EHU00734.1 - 3e-67 226.6 0.2 5.3e-67 225.8 0.2 1.4 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 EHU00734.1 - 2.4e-45 154.2 0.0 4.8e-45 153.2 0.0 1.5 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_9 PF13426.7 EHU00734.1 - 2.9e-08 33.9 0.2 7.6e-08 32.5 0.2 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EHU00734.1 - 2.9e-06 27.2 0.2 2e-05 24.6 0.0 2.5 3 0 0 3 3 3 1 PAS fold PAS_4 PF08448.10 EHU00734.1 - 0.0003 21.0 0.0 0.0019 18.4 0.0 2.4 3 0 0 3 3 3 1 PAS fold PAS_10 PF13596.6 EHU00734.1 - 0.0014 19.2 0.0 0.014 16.0 0.1 2.5 2 0 0 2 2 2 1 PAS domain GGDEF_2 PF17853.1 EHU00734.1 - 0.048 13.9 0.2 0.18 12.0 0.2 2.1 1 1 0 1 1 1 0 GGDEF-like domain PAS_8 PF13188.7 EHU00734.1 - 0.052 13.6 0.1 4.3 7.5 0.0 2.6 2 0 0 2 2 2 0 PAS domain ECH_1 PF00378.20 EHU00735.1 - 5.4e-18 65.2 0.0 6.9e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EHU00735.1 - 5.6e-11 42.5 0.0 8.6e-11 41.9 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Aldolase_II PF00596.21 EHU00736.1 - 7e-45 153.3 0.3 8.9e-45 152.9 0.3 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Rick_17kDa_Anti PF05433.15 EHU00737.1 - 2.5e-08 33.6 19.1 3.6e-08 33.1 19.1 1.3 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 EHU00737.1 - 3.8e-05 23.6 19.3 6e-05 23.0 19.3 1.4 1 0 0 1 1 1 1 Glycine zipper Gly-zipper_YMGG PF13441.6 EHU00737.1 - 0.00028 20.6 20.2 0.0063 16.2 3.7 1.9 1 1 1 2 2 2 2 YMGG-like Gly-zipper LPAM_1 PF08139.12 EHU00737.1 - 0.0009 19.6 2.2 0.0022 18.4 2.2 1.7 1 0 0 1 1 1 1 Prokaryotic membrane lipoprotein lipid attachment site Bacteriocin_IIc PF10439.9 EHU00737.1 - 0.17 12.0 14.2 0.24 11.5 14.2 1.4 1 1 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_OmpA PF13436.6 EHU00737.1 - 0.46 10.3 22.9 0.59 10.0 7.4 2.1 1 1 1 2 2 2 0 Glycine-zipper domain SUI1 PF01253.22 EHU00738.1 - 1.5e-17 63.8 0.3 2e-17 63.5 0.3 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 OMPdecase PF00215.24 EHU00739.1 - 4.1e-51 173.8 0.0 4.5e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family TPR_2 PF07719.17 EHU00740.1 - 7.8e-12 44.4 1.4 0.0027 17.7 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat Rubredoxin_2 PF18073.1 EHU00740.1 - 8.7e-12 44.6 6.8 1.4e-11 43.9 6.8 1.3 1 0 0 1 1 1 1 Rubredoxin metal binding domain TPR_19 PF14559.6 EHU00740.1 - 1.5e-11 44.6 12.9 2.4e-05 24.7 0.1 4.9 2 2 5 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 EHU00740.1 - 5.6e-11 42.3 17.5 0.19 12.7 0.0 7.8 4 2 3 8 8 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 EHU00740.1 - 1.4e-10 41.7 3.1 0.69 10.6 0.0 5.4 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 EHU00740.1 - 9.4e-10 37.8 9.6 0.088 12.9 0.0 6.2 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 EHU00740.1 - 1.4e-08 34.2 0.3 0.022 14.5 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EHU00740.1 - 1.4e-07 31.7 5.6 0.0003 21.0 0.8 4.6 4 1 2 6 6 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EHU00740.1 - 6.8e-07 29.4 1.8 0.00084 19.5 0.0 4.0 3 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EHU00740.1 - 7.8e-07 28.8 2.7 0.039 14.2 0.0 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 EHU00740.1 - 1.2e-05 24.9 0.0 0.005 16.5 0.0 3.6 3 0 0 3 3 3 1 TPR repeat TPR_6 PF13174.6 EHU00740.1 - 0.00018 22.0 10.7 3.8 8.3 0.0 6.9 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 EHU00740.1 - 0.00047 19.9 4.7 10 6.1 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 EHU00740.1 - 0.0014 18.4 11.7 0.058 13.1 4.4 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat-like domain NARP1 PF12569.8 EHU00740.1 - 0.0022 17.0 2.1 0.086 11.7 0.7 2.1 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 SPG48 PF14764.6 EHU00740.1 - 0.0095 16.4 0.0 0.055 14.0 0.0 2.1 2 0 0 2 2 2 1 AP-5 complex subunit, vesicle trafficking HrpB1_HrpK PF09613.10 EHU00740.1 - 0.01 15.5 2.0 0.053 13.2 0.7 2.4 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_20 PF14561.6 EHU00740.1 - 0.049 14.0 14.8 2.8 8.3 0.3 4.9 3 1 3 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 EHU00740.1 - 0.07 13.8 0.4 1.4e+02 3.6 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 EHU00740.1 - 0.073 13.5 0.0 16 6.2 0.0 3.8 2 1 2 4 4 4 0 Tetratricopeptide repeat zinc_ribbon_15 PF17032.5 EHU00740.1 - 0.094 13.5 0.1 0.17 12.6 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon family HypA PF01155.19 EHU00740.1 - 0.11 12.5 0.1 0.39 10.7 0.0 1.9 2 0 0 2 2 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TPR_9 PF13371.6 EHU00740.1 - 0.11 12.6 7.3 2.4 8.4 0.3 4.0 2 1 1 4 4 4 0 Tetratricopeptide repeat PPR PF01535.20 EHU00740.1 - 0.39 11.1 4.8 22 5.6 0.1 4.4 6 0 0 6 6 4 0 PPR repeat zf-CCHC_3 PF13917.6 EHU00740.1 - 0.48 10.4 4.3 1.2 9.1 4.3 1.7 1 0 0 1 1 1 0 Zinc knuckle LapA_dom PF06305.11 EHU00741.1 - 2.9e-19 68.6 0.5 2.9e-19 68.6 0.5 2.0 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain DsbD_2 PF13386.6 EHU00741.1 - 0.0077 16.2 2.5 0.0092 15.9 2.5 1.1 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region Tmemb_170 PF10190.9 EHU00741.1 - 0.041 14.2 2.2 0.049 14.0 2.2 1.1 1 0 0 1 1 1 0 Putative transmembrane protein 170 G6B PF15096.6 EHU00741.1 - 0.065 13.0 0.0 0.079 12.7 0.0 1.1 1 0 0 1 1 1 0 G6B family Yip1 PF04893.17 EHU00741.1 - 0.083 12.6 6.9 0.097 12.4 6.9 1.1 1 0 0 1 1 1 0 Yip1 domain DUF948 PF06103.11 EHU00741.1 - 0.17 12.1 0.8 2.8 8.3 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4389 PF14333.6 EHU00741.1 - 4 7.4 8.1 0.88 9.5 1.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4389) PhoR PF11808.8 EHU00741.1 - 8.7 6.8 9.1 0.37 11.2 1.0 2.0 1 1 1 2 2 2 0 Phosphate regulon sensor protein PhoR PAP2 PF01569.21 EHU00742.1 - 3.3e-27 94.9 1.5 3.3e-27 94.9 1.5 1.9 1 1 0 2 2 2 1 PAP2 superfamily GTP_cyclohydro2 PF00925.20 EHU00743.1 - 2.4e-68 228.9 0.0 2.8e-68 228.6 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase II Aconitase PF00330.20 EHU00744.1 - 4.9e-182 606.0 0.0 6.3e-182 605.7 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EHU00744.1 - 7.1e-48 162.3 0.0 1.6e-47 161.1 0.0 1.6 2 0 0 2 2 2 1 Aconitase C-terminal domain LysR_substrate PF03466.20 EHU00747.1 - 5e-41 140.4 0.0 6.6e-41 140.0 0.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EHU00747.1 - 1.2e-15 57.2 0.0 2.1e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Topoisom_bac PF01131.20 EHU00748.1 - 3.9e-129 431.3 2.5 7e-129 430.4 0.2 2.1 2 0 0 2 2 2 1 DNA topoisomerase Topo_Zn_Ribbon PF08272.11 EHU00748.1 - 3.8e-39 132.1 0.2 9e-24 82.9 2.1 2.6 2 0 0 2 2 2 2 Topoisomerase I zinc-ribbon-like Toprim PF01751.22 EHU00748.1 - 3.5e-33 113.9 0.1 8.7e-33 112.6 0.1 1.7 1 0 0 1 1 1 1 Toprim domain zf-C4_Topoisom PF01396.19 EHU00748.1 - 2.2e-19 68.9 16.3 2.9e-11 42.9 2.1 4.5 4 0 0 4 4 4 2 Topoisomerase DNA binding C4 zinc finger Toprim_4 PF13662.6 EHU00748.1 - 0.056 13.9 0.0 0.42 11.1 0.0 2.5 2 0 0 2 2 2 0 Toprim domain Toprim_2 PF13155.6 EHU00748.1 - 0.097 13.1 0.0 0.35 11.3 0.0 1.9 1 0 0 1 1 1 0 Toprim-like Zn_ribbon_recom PF13408.6 EHU00748.1 - 0.13 12.8 11.5 0.2 12.2 0.0 3.6 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain DZR PF12773.7 EHU00748.1 - 0.41 10.7 4.7 19 5.3 4.7 2.6 1 1 0 1 1 1 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 EHU00748.1 - 4.5 7.3 8.8 2.7 8.0 0.0 3.3 2 1 3 5 5 5 0 Putative transposase DNA-binding domain YhfH PF14149.6 EHU00748.1 - 7.4 6.6 7.7 51 4.0 0.4 3.6 3 0 0 3 3 3 0 YhfH-like protein DUF2498 PF10692.9 EHU00749.1 - 1e-35 121.4 0.0 1.1e-35 121.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2498) Peptidase_S49_N PF08496.10 EHU00750.1 - 2.3e-60 203.1 0.8 3.7e-60 202.4 0.8 1.3 1 0 0 1 1 1 1 Peptidase family S49 N-terminal Peptidase_S49 PF01343.18 EHU00750.1 - 3.5e-45 153.7 0.0 6.9e-45 152.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S49 SDH_sah PF01972.16 EHU00750.1 - 0.007 15.4 0.1 0.012 14.7 0.1 1.3 1 0 0 1 1 1 1 Serine dehydrogenase proteinase Metal_resist PF13801.6 EHU00750.1 - 0.09 13.0 3.2 0.093 12.9 0.2 2.5 3 0 0 3 3 3 0 Heavy-metal resistance UPF0239 PF06783.11 EHU00750.1 - 0.092 12.9 4.3 0.32 11.2 4.3 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0239) TMF_TATA_bd PF12325.8 EHU00750.1 - 1.7 8.9 7.9 0.92 9.7 0.1 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding adh_short PF00106.25 EHU00751.1 - 2.8e-50 170.5 0.0 3.2e-50 170.3 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EHU00751.1 - 1.9e-40 138.9 0.0 4.1e-40 137.8 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EHU00751.1 - 3.1e-17 63.1 0.1 4e-17 62.7 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EHU00751.1 - 0.00083 18.9 0.3 0.023 14.2 0.3 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EHU00751.1 - 0.04 13.1 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1776 PF08643.10 EHU00751.1 - 0.045 13.1 0.0 0.051 13.0 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) CHASE2 PF05226.11 EHU00751.1 - 0.11 12.1 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 CHASE2 domain CobA_CobO_BtuR PF02572.15 EHU00752.1 - 4.1e-59 199.7 0.0 5.3e-59 199.3 0.0 1.1 1 0 0 1 1 1 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Co_AT_N PF12557.8 EHU00752.1 - 5e-07 29.5 5.3 1.1e-06 28.4 5.3 1.6 1 0 0 1 1 1 1 Cob(I)alamin adenosyltransferase N terminal Nuc_deoxyri_tr2 PF15891.5 EHU00752.1 - 0.13 12.5 0.1 0.46 10.8 0.0 1.9 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase like CitMHS PF03600.16 EHU00753.1 - 6.3e-49 166.8 56.1 2.3e-48 165.0 50.8 2.7 2 1 0 2 2 2 1 Citrate transporter Na_H_antiporter PF03553.14 EHU00753.1 - 3.1e-09 36.5 39.7 1.3e-06 27.9 19.5 2.3 2 0 0 2 2 2 2 Na+/H+ antiporter family DUF3357 PF11837.8 EHU00753.1 - 1.3 9.5 3.1 18 5.8 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) PP-binding PF00550.25 EHU00754.1 - 0.022 15.1 0.1 0.033 14.5 0.1 1.3 1 0 0 1 1 1 0 Phosphopantetheine attachment site PseudoU_synth_2 PF00849.22 EHU00755.1 - 7.7e-17 61.8 0.0 2.2e-16 60.4 0.0 1.8 2 1 0 2 2 2 1 RNA pseudouridylate synthase S4 PF01479.25 EHU00755.1 - 6.1e-11 41.9 0.2 2.8e-10 39.7 0.1 2.3 2 0 0 2 2 2 1 S4 domain LPAM_1 PF08139.12 EHU00756.1 - 0.066 13.7 1.3 0.14 12.7 1.3 1.6 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Trypsin_2 PF13365.6 EHU00756.1 - 0.074 13.9 0.9 0.29 12.0 0.9 1.9 1 1 0 1 1 1 0 Trypsin-like peptidase domain SLH PF00395.20 EHU00756.1 - 0.34 10.9 1.0 5.3 7.1 0.0 2.6 3 0 0 3 3 3 0 S-layer homology domain Sua5_yciO_yrdC PF01300.18 EHU00757.1 - 1.4e-44 151.8 0.0 1.6e-44 151.6 0.0 1.0 1 0 0 1 1 1 1 Telomere recombination Y_Y_Y PF07495.13 EHU00757.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Y_Y_Y domain PHP PF02811.19 EHU00758.1 - 1.3e-09 38.6 0.0 2.4e-09 37.7 0.0 1.3 1 1 0 1 1 1 1 PHP domain Chorismate_bind PF00425.18 EHU00759.1 - 1.9e-85 286.5 0.0 2.8e-85 286.0 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 EHU00759.1 - 8.7e-16 58.4 0.0 3.6e-14 53.2 0.0 2.9 3 0 0 3 3 3 1 Anthranilate synthase component I, N terminal region GATase PF00117.28 EHU00760.1 - 9.7e-45 152.7 0.0 1.2e-44 152.4 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EHU00760.1 - 2.5e-08 33.9 0.6 9.1e-08 32.1 0.6 1.8 1 1 0 1 1 1 1 Peptidase C26 Glycos_transf_3 PF00591.21 EHU00761.1 - 4.1e-99 331.3 0.0 5.4e-99 330.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 EHU00761.1 - 1.6e-16 59.9 0.3 9.2e-16 57.5 0.1 2.4 3 0 0 3 3 3 1 Glycosyl transferase family, helical bundle domain DSHCT PF08148.12 EHU00761.1 - 0.22 11.1 1.3 9.7 5.8 0.0 2.8 3 1 0 3 3 3 0 DSHCT (NUC185) domain IGPS PF00218.21 EHU00762.1 - 9.3e-96 319.9 0.0 1.2e-95 319.5 0.0 1.1 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 EHU00762.1 - 4.2e-59 199.6 0.0 6.9e-59 198.9 0.0 1.3 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase HHH_4 PF14490.6 EHU00762.1 - 0.075 13.0 0.0 0.54 10.3 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix containing domain QRPTase_C PF01729.19 EHU00762.1 - 0.16 11.7 0.1 0.47 10.2 0.1 1.8 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain PALP PF00291.25 EHU00763.1 - 6.1e-54 183.4 1.7 7.1e-54 183.2 1.7 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Trp_syntA PF00290.20 EHU00764.1 - 8.5e-96 319.8 0.0 9.4e-96 319.6 0.0 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain His_biosynth PF00977.21 EHU00764.1 - 0.007 15.8 0.0 0.059 12.8 0.0 2.1 3 0 0 3 3 3 1 Histidine biosynthesis protein Amidohydro_2 PF04909.14 EHU00764.1 - 0.1 12.3 0.0 0.46 10.2 0.0 2.1 1 1 0 1 1 1 0 Amidohydrolase BON PF04972.17 EHU00765.1 - 1.5e-22 79.7 1.3 2e-22 79.3 1.3 1.2 1 0 0 1 1 1 1 BON domain DUF4995 PF16386.5 EHU00765.1 - 0.1 12.6 0.4 0.18 11.8 0.2 1.6 1 1 1 2 2 2 0 Domain of unknown function OmpW PF03922.14 EHU00766.1 - 6.6e-67 225.1 0.1 7.5e-67 225.0 0.1 1.0 1 0 0 1 1 1 1 OmpW family OMP_b-brl PF13505.6 EHU00766.1 - 2.9e-14 53.6 2.7 3.7e-14 53.3 2.7 1.1 1 0 0 1 1 1 1 Outer membrane protein beta-barrel domain Opacity PF02462.15 EHU00766.1 - 1.3e-05 25.4 0.2 2.9e-05 24.2 0.1 1.4 1 1 0 1 1 1 1 Opacity family porin protein OMP_b-brl_2 PF13568.6 EHU00766.1 - 0.00045 20.3 1.1 0.01 15.9 0.3 2.2 1 1 1 2 2 2 2 Outer membrane protein beta-barrel domain OprF PF05736.11 EHU00766.1 - 0.016 15.0 0.1 0.025 14.3 0.1 1.3 1 0 0 1 1 1 0 OprF membrane domain CxxCxxCC PF03692.15 EHU00767.1 - 2.3e-11 44.2 1.6 3.2e-11 43.8 1.6 1.2 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain UPF0259 PF06790.11 EHU00768.1 - 2.6e-84 282.9 22.1 2.9e-84 282.7 22.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0259) IspA PF04279.15 EHU00769.1 - 1.1e-66 224.3 23.7 1.3e-66 224.2 23.7 1.0 1 0 0 1 1 1 1 Intracellular septation protein A stn_TNFRSF12A PF12191.8 EHU00769.1 - 0.056 13.7 1.3 2.9 8.1 0.1 2.3 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain MerC PF03203.14 EHU00769.1 - 3.6 8.1 16.4 1.9 8.9 6.6 2.3 1 1 0 2 2 2 0 MerC mercury resistance protein PepSY_TM PF03929.16 EHU00769.1 - 9.9 5.7 11.4 0.33 10.6 0.9 3.0 2 2 1 3 3 3 0 PepSY-associated TM region 4HBT PF03061.22 EHU00770.1 - 8e-19 67.8 0.1 1.2e-18 67.3 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily MaoC_dehydratas PF01575.19 EHU00770.1 - 0.0017 17.9 0.1 0.0022 17.6 0.1 1.2 1 0 0 1 1 1 1 MaoC like domain TonB_N PF16031.5 EHU00771.1 - 1.7e-19 70.7 78.8 8.2e-17 62.0 78.8 2.3 1 1 0 1 1 1 1 TonB polyproline region TonB_C PF03544.14 EHU00771.1 - 2.5e-16 59.9 0.0 5.2e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal Dockerin_1 PF00404.18 EHU00771.1 - 0.19 12.0 0.5 0.34 11.1 0.5 1.3 1 0 0 1 1 1 0 Dockerin type I domain DDE_Tnp_1 PF01609.21 EHU00772.1 - 5.5e-20 71.9 0.0 1e-19 71.0 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain YCII PF03795.14 EHU00773.1 - 2e-29 101.9 0.0 2.2e-29 101.7 0.0 1.0 1 0 0 1 1 1 1 YCII-related domain DUF1330 PF07045.11 EHU00773.1 - 0.00039 20.7 0.0 0.00045 20.5 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1330) YoqO PF14037.6 EHU00774.1 - 0.0071 16.9 0.4 0.0079 16.7 0.4 1.1 1 0 0 1 1 1 1 YoqO-like protein TrbC PF04956.13 EHU00774.1 - 0.047 13.9 2.2 0.054 13.7 2.2 1.1 1 0 0 1 1 1 0 TrbC/VIRB2 family SKG6 PF08693.10 EHU00774.1 - 0.22 11.0 0.5 0.22 11.0 0.5 2.5 2 1 1 3 3 3 0 Transmembrane alpha-helix domain DUF4131 PF13567.6 EHU00774.1 - 0.69 9.5 3.3 0.74 9.4 3.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF1289 PF06945.13 EHU00775.1 - 9.2 6.2 7.0 6.6 6.6 4.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) PLDc_2 PF13091.6 EHU00776.1 - 2.2e-35 121.5 0.0 3.6e-21 75.4 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EHU00776.1 - 9.1e-15 54.1 0.1 6.1e-07 29.4 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_N PF13396.6 EHU00776.1 - 7.2e-08 32.2 6.1 2.3e-07 30.7 6.1 1.9 1 0 0 1 1 1 1 Phospholipase_D-nuclease N-terminal CRPA PF05745.11 EHU00776.1 - 0.24 11.4 0.7 0.44 10.5 0.7 1.3 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) DUF440 PF04269.12 EHU00777.1 - 1.6e-44 150.3 0.1 1.8e-44 150.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF440 Lac_bphage_repr PF06543.12 EHU00777.1 - 0.067 13.2 0.3 7.2 6.7 0.2 2.3 2 0 0 2 2 2 0 Lactococcus bacteriophage repressor ABC_tran PF00005.27 EHU00778.1 - 1.2e-32 113.3 0.0 1.6e-32 112.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EHU00778.1 - 2.2e-18 66.5 0.1 4.3e-18 65.6 0.1 1.5 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_22 PF13401.6 EHU00778.1 - 0.00012 22.3 0.1 0.00088 19.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 EHU00778.1 - 0.00021 20.8 0.0 0.00035 20.1 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EHU00778.1 - 0.0006 19.7 0.2 0.75 9.5 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EHU00778.1 - 0.0048 17.3 0.1 0.007 16.8 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EHU00778.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA PF00004.29 EHU00778.1 - 0.019 15.4 0.0 0.043 14.3 0.0 1.6 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EHU00778.1 - 0.023 14.6 0.3 0.045 13.7 0.3 1.5 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 EHU00778.1 - 0.027 13.7 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 EHU00778.1 - 0.027 14.2 0.1 0.048 13.4 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain PRK PF00485.18 EHU00778.1 - 0.029 14.1 0.4 0.2 11.4 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.23 EHU00778.1 - 0.037 14.1 0.1 0.071 13.2 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase TniB PF05621.11 EHU00778.1 - 0.052 12.9 0.6 0.99 8.8 0.1 2.2 2 0 0 2 2 2 0 Bacterial TniB protein MobB PF03205.14 EHU00778.1 - 0.098 12.6 0.2 0.21 11.5 0.2 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.22 EHU00778.1 - 0.1 13.0 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_13 PF13166.6 EHU00778.1 - 0.17 10.5 0.2 0.89 8.1 0.1 1.8 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 EHU00778.1 - 0.2 11.3 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activat PF00158.26 EHU00778.1 - 0.23 11.2 0.3 0.83 9.3 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_ATPase PF09818.9 EHU00778.1 - 0.28 9.9 0.5 6.6 5.4 0.2 2.3 2 1 0 2 2 2 0 Predicted ATPase of the ABC class ABC_tran PF00005.27 EHU00779.1 - 7.7e-28 97.7 0.0 1e-27 97.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 EHU00779.1 - 1.4e-21 76.8 0.1 2.5e-21 76.0 0.1 1.5 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 EHU00779.1 - 1.7e-06 28.1 0.8 5.2e-06 26.5 0.0 2.0 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EHU00779.1 - 0.00015 21.3 0.2 0.00028 20.4 0.2 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 EHU00779.1 - 0.027 14.2 0.2 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_29 PF13555.6 EHU00779.1 - 0.077 12.8 0.8 0.16 11.8 0.2 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EHU00779.1 - 0.32 11.3 0.9 1.6 9.0 0.9 2.0 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.17 EHU00779.1 - 0.36 10.9 1.3 0.66 10.0 0.6 1.7 1 1 1 2 2 2 0 Helicase HerA, central domain BPD_transp_1 PF00528.22 EHU00780.1 - 8e-29 100.7 10.0 8e-29 100.7 10.0 2.3 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 EHU00780.1 - 1.4e-14 53.7 1.5 1.4e-14 53.7 1.5 3.5 4 0 0 4 4 4 1 N-terminal TM domain of oligopeptide transport permease C Ac76 PF05814.11 EHU00780.1 - 0.24 11.4 0.2 0.24 11.4 0.2 3.2 3 1 1 4 4 4 0 Orf76 (Ac76) BPD_transp_1 PF00528.22 EHU00781.1 - 3.3e-38 131.3 18.2 3.3e-38 131.3 18.2 1.7 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF2897 PF11446.8 EHU00781.1 - 0.088 12.7 0.5 0.31 11.0 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) SBP_bac_5 PF00496.22 EHU00782.1 - 6.8e-86 288.6 8.4 1.1e-85 287.9 8.4 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle SBP_bac_5 PF00496.22 EHU00783.1 - 4.5e-84 282.6 10.0 5.5e-84 282.3 10.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle HTH_Tnp_1 PF01527.20 EHU00784.1 - 1.4e-16 60.6 0.0 2.1e-15 56.8 0.0 2.1 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.6 EHU00784.1 - 7.9e-08 31.9 0.0 0.017 14.9 0.0 2.3 2 0 0 2 2 2 2 Homeodomain-like domain HTH_28 PF13518.6 EHU00784.1 - 5.9e-05 23.1 0.0 0.019 15.1 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain MarR_2 PF12802.7 EHU00784.1 - 0.025 14.4 0.1 2.1 8.3 0.0 2.7 3 0 0 3 3 3 0 MarR family CENP-B_N PF04218.13 EHU00784.1 - 0.042 13.5 0.0 10 5.9 0.0 2.3 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain HTH_29 PF13551.6 EHU00784.1 - 0.11 12.6 2.1 0.27 11.3 0.0 2.3 3 0 0 3 3 3 0 Winged helix-turn helix Gp138_N PF18352.1 EHU00785.1 - 5.7e-42 141.8 0.6 1.6e-41 140.4 0.1 1.9 2 1 0 2 2 2 1 Phage protein Gp138 N-terminal domain Phage_spike PF18715.1 EHU00785.1 - 0.0066 16.5 3.7 0.45 10.6 1.5 3.4 3 0 0 3 3 3 1 Phage spike trimer HTH_Tnp_1 PF01527.20 EHU00787.1 - 1.2e-14 54.3 0.0 3.9e-14 52.7 0.0 1.8 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.6 EHU00787.1 - 0.062 13.1 0.0 0.15 11.9 0.0 1.6 2 0 0 2 2 2 0 Homeodomain-like domain TnpB_IS66 PF05717.13 EHU00788.1 - 2.9e-40 136.3 0.0 3.3e-40 136.1 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHU00789.1 - 1.3e-24 87.2 1.0 2.4e-23 83.0 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family zf-IS66 PF13005.7 EHU00789.1 - 1.9e-14 53.8 2.8 4e-14 52.7 2.8 1.6 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU00789.1 - 1.6e-12 48.0 8.3 3.5e-12 46.9 8.3 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Csm1_N PF18504.1 EHU00789.1 - 0.0069 16.7 3.3 0.03 14.6 0.6 2.5 1 1 1 2 2 2 1 Csm1 N-terminal domain Exonuc_VII_L PF02601.15 EHU00789.1 - 0.01 15.4 0.5 0.013 15.1 0.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit LXG PF04740.12 EHU00789.1 - 0.041 13.6 2.9 0.1 12.3 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily FAM184 PF15665.5 EHU00789.1 - 0.061 13.1 7.2 0.09 12.5 7.2 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Zn-ribbon_8 PF09723.10 EHU00789.1 - 0.073 13.2 2.1 0.28 11.3 0.2 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Tho2 PF11262.8 EHU00789.1 - 0.077 12.2 1.4 0.11 11.7 1.4 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FUSC PF04632.12 EHU00789.1 - 0.081 11.4 7.9 0.032 12.8 5.2 1.6 2 0 0 2 2 2 0 Fusaric acid resistance protein family PyrI_C PF02748.15 EHU00789.1 - 0.089 12.7 0.4 0.18 11.7 0.4 1.4 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain TackOD1 PF18551.1 EHU00789.1 - 0.3 10.8 3.1 0.11 12.1 0.4 1.6 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 USP8_interact PF08941.10 EHU00789.1 - 0.3 10.9 2.4 1.3 8.8 2.5 1.9 2 0 0 2 2 2 0 USP8 interacting ERM PF00769.19 EHU00789.1 - 0.49 10.2 8.3 0.68 9.7 8.3 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HalX PF08663.10 EHU00789.1 - 0.5 10.7 5.4 0.078 13.3 1.1 1.8 2 0 0 2 2 2 0 HalX domain DUF1192 PF06698.11 EHU00789.1 - 0.77 9.9 6.0 2 8.5 0.2 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF1192) TMF_DNA_bd PF12329.8 EHU00789.1 - 1.3 9.1 7.7 4.4 7.4 0.5 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.12 EHU00789.1 - 1.7 9.3 9.3 7.7 7.2 2.3 2.8 1 1 1 2 2 2 0 SlyX TMPIT PF07851.13 EHU00789.1 - 1.8 7.8 3.4 2.6 7.2 3.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein MerR-DNA-bind PF09278.11 EHU00789.1 - 8 7.1 7.4 31 5.2 0.1 2.6 2 0 0 2 2 2 0 MerR, DNA binding Peptidase_S66 PF02016.15 EHU00790.1 - 3.6e-21 75.5 0.0 6e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 LD-carboxypeptidase N-terminal domain Peptidase_S66C PF17676.1 EHU00790.1 - 5.6e-21 75.4 0.0 1e-20 74.5 0.0 1.4 1 0 0 1 1 1 1 LD-carboxypeptidase C-terminal domain DUF1834 PF08873.11 EHU00790.1 - 0.055 13.2 0.0 0.075 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1834) TOBE_2 PF08402.10 EHU00791.1 - 8.1e-10 38.7 0.1 9.6e-10 38.5 0.1 1.1 1 0 0 1 1 1 1 TOBE domain TOBE PF03459.17 EHU00791.1 - 0.021 15.1 0.2 0.035 14.4 0.2 1.3 1 0 0 1 1 1 0 TOBE domain LamB PF02264.15 EHU00792.1 - 8.2e-144 480.2 18.8 9.3e-144 480.0 18.8 1.0 1 0 0 1 1 1 1 LamB porin MalM PF07148.12 EHU00793.1 - 8.7e-51 171.2 0.0 1.5e-50 170.4 0.0 1.4 1 0 0 1 1 1 1 Maltose operon periplasmic protein precursor (MalM) SgrR_N PF12793.7 EHU00793.1 - 0.16 12.2 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 Sugar transport-related sRNA regulator N-term TPR_MalT PF17874.1 EHU00793.1 - 0.19 11.0 0.2 0.47 9.8 0.0 1.7 2 0 0 2 2 2 0 MalT-like TPR region Glyco_hydro_77 PF02446.17 EHU00794.1 - 8.9e-130 433.7 0.0 1.1e-129 433.3 0.0 1.0 1 0 0 1 1 1 1 4-alpha-glucanotransferase Phosphorylase PF00343.20 EHU00795.1 - 5.3e-299 993.5 0.0 6.1e-299 993.3 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase TPR_MalT PF17874.1 EHU00796.1 - 8.1e-111 370.6 28.6 8.1e-111 370.6 28.6 2.2 2 1 0 2 2 2 1 MalT-like TPR region AAA_16 PF13191.6 EHU00796.1 - 6.6e-06 26.6 0.1 6.6e-06 26.6 0.1 4.6 4 1 1 5 5 5 1 AAA ATPase domain TPR_19 PF14559.6 EHU00796.1 - 1.8e-05 25.1 26.0 0.0099 16.4 0.6 6.1 3 3 2 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 EHU00796.1 - 2.4e-05 24.5 25.4 0.00086 19.5 1.3 5.9 4 2 0 4 4 4 2 Tetratricopeptide repeat AAA_22 PF13401.6 EHU00796.1 - 0.0015 18.8 1.5 0.028 14.7 0.0 3.3 2 1 1 3 3 3 1 AAA domain TPR_8 PF13181.6 EHU00796.1 - 0.002 18.2 0.8 12 6.4 0.1 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF1843 PF08898.10 EHU00796.1 - 0.0028 18.1 0.0 2 9.0 0.0 3.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1843) RPN7 PF10602.9 EHU00796.1 - 0.0067 16.1 0.0 1.5 8.5 0.0 2.3 1 1 1 2 2 2 1 26S proteasome subunit RPN7 ATPase_2 PF01637.18 EHU00796.1 - 0.0068 16.3 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 EHU00796.1 - 0.012 15.1 0.1 0.079 12.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EHU00796.1 - 0.11 12.4 3.0 0.19 11.6 0.1 2.9 3 1 0 3 3 3 0 NACHT domain AAA_19 PF13245.6 EHU00796.1 - 0.15 12.4 0.0 0.44 10.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain TPR_4 PF07721.14 EHU00796.1 - 0.15 12.8 35.7 9.2 7.2 0.0 7.9 8 0 0 8 8 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EHU00796.1 - 0.54 10.5 6.7 15 5.9 0.0 4.9 5 1 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 MFS_1 PF07690.16 EHU00797.1 - 1e-34 120.1 47.0 2e-20 73.0 19.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EHU00797.1 - 5.6e-05 21.6 7.3 0.0018 16.7 0.3 2.4 1 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family DUF4381 PF14316.6 EHU00797.1 - 2.2 8.5 5.7 0.15 12.3 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF3094 PF11293.8 EHU00797.1 - 2.5 7.9 8.9 4.6 7.0 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3094) Acetyltransf_1 PF00583.25 EHU00798.1 - 7.3e-06 26.2 0.0 9.7e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EHU00798.1 - 0.0032 17.4 0.0 0.0043 17.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EHU00798.1 - 0.041 14.6 0.0 0.049 14.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EHU00798.1 - 0.11 12.6 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EHU00798.1 - 0.15 12.5 0.1 0.34 11.4 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain GHL10 PF02638.15 EHU00799.1 - 2.9e-120 401.1 1.9 3.5e-120 400.8 1.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 Melibiase PF02065.18 EHU00799.1 - 3.5e-05 22.9 0.0 5.8e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Melibiase DUF4434 PF14488.6 EHU00799.1 - 0.0023 18.0 0.0 0.0041 17.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4434) Glyco_hydro_66 PF13199.6 EHU00799.1 - 0.0085 14.8 0.0 0.011 14.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 66 Alpha_L_fucos PF01120.17 EHU00799.1 - 0.045 13.2 0.0 0.069 12.6 0.0 1.3 1 0 0 1 1 1 0 Alpha-L-fucosidase GHL15 PF14885.6 EHU00799.1 - 0.048 13.6 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 15 DUF2256 PF10013.9 EHU00800.1 - 8.5e-17 61.0 11.6 9.8e-17 60.8 11.6 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) Ecl1 PF12855.7 EHU00800.1 - 0.0058 17.8 0.9 0.0072 17.5 0.9 1.2 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 EHU00800.1 - 0.02 14.9 6.4 0.029 14.4 6.4 1.3 1 0 0 1 1 1 0 MYND finger Molybdopterin PF00384.22 EHU00801.1 - 3.2e-29 102.2 0.0 5.8e-29 101.3 0.0 1.4 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 EHU00801.1 - 1.8e-09 37.6 0.0 1.4e-08 34.7 0.0 2.4 2 1 0 2 2 2 1 Molydopterin dinucleotide binding domain TPP_enzyme_M PF00205.22 EHU00801.1 - 0.012 15.4 0.1 4.9 6.9 0.0 2.7 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, central domain CpcD PF01383.21 EHU00801.1 - 0.024 14.9 0.0 0.072 13.4 0.0 1.8 1 0 0 1 1 1 0 CpcD/allophycocyanin linker domain MgtC PF02308.16 EHU00802.1 - 2.9e-34 118.0 13.4 3.9e-34 117.6 13.1 1.4 1 1 0 1 1 1 1 MgtC family ACT_4 PF13291.6 EHU00802.1 - 0.11 13.1 0.0 0.32 11.6 0.0 1.8 2 0 0 2 2 2 0 ACT domain NLPC_P60 PF00877.19 EHU00803.1 - 5e-23 81.1 0.1 6.9e-23 80.7 0.1 1.2 1 0 0 1 1 1 1 NlpC/P60 family LPAM_1 PF08139.12 EHU00803.1 - 0.12 12.9 1.0 0.12 12.9 1.0 1.8 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site adh_short_C2 PF13561.6 EHU00805.1 - 1.9e-55 188.0 0.1 2.1e-55 187.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EHU00805.1 - 3.3e-53 180.1 0.1 3.8e-53 179.9 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EHU00805.1 - 7.4e-09 35.8 0.5 1e-08 35.3 0.5 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 EHU00805.1 - 0.063 12.6 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Methyltransf_25 PF13649.6 EHU00805.1 - 0.09 13.5 0.2 0.22 12.3 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain 3HCDH_N PF02737.18 EHU00805.1 - 0.099 12.5 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 EHU00806.1 - 1.6e-66 224.2 1.5 1.8e-66 224.1 1.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EHU00806.1 - 1.7e-44 151.6 0.1 2.2e-44 151.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EHU00806.1 - 2.5e-16 60.1 1.2 3.6e-16 59.6 1.2 1.1 1 0 0 1 1 1 1 KR domain LRR_RI_capping PF18779.1 EHU00806.1 - 0.005 16.5 0.1 0.0093 15.6 0.1 1.4 1 0 0 1 1 1 1 Capping Ribonuclease inhibitor Leucine Rich Repeat MFS_1 PF07690.16 EHU00807.1 - 6.6e-35 120.7 57.0 6.1e-30 104.3 27.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EHU00807.1 - 3e-22 79.1 20.3 3.9e-22 78.8 20.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Ribonuc_L-PSP PF01042.21 EHU00809.1 - 1.5e-21 76.6 0.0 1.8e-21 76.4 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DAO PF01266.24 EHU00810.1 - 2.9e-63 214.6 2.0 3.7e-63 214.2 2.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EHU00810.1 - 5.4e-07 29.0 2.7 4.3e-06 26.1 4.2 1.7 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EHU00810.1 - 2e-06 27.9 0.0 5.1e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EHU00810.1 - 0.0008 18.6 0.1 0.017 14.2 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 EHU00810.1 - 0.0036 16.6 0.1 0.028 13.7 0.1 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 EHU00810.1 - 0.0043 16.3 0.0 0.013 14.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EHU00810.1 - 0.0081 15.4 0.5 0.038 13.3 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EHU00810.1 - 0.012 14.8 0.5 0.022 14.0 0.5 1.4 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 EHU00810.1 - 0.066 12.5 0.1 0.15 11.4 0.0 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 EHU00810.1 - 0.068 12.8 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 EHU00810.1 - 0.14 10.9 2.3 0.24 10.0 1.1 1.8 2 0 0 2 2 2 0 HI0933-like protein Mqo PF06039.15 EHU00810.1 - 0.26 9.8 0.0 0.34 9.4 0.0 1.1 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Ala_racemase_N PF01168.20 EHU00811.1 - 7.6e-31 107.5 0.4 1.1e-30 106.9 0.4 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.6 EHU00811.1 - 3.2e-20 72.6 0.0 8.7e-20 71.2 0.0 1.8 1 0 0 1 1 1 1 Putative serine dehydratase domain AP_endonuc_2 PF01261.24 EHU00811.1 - 0.00043 19.8 0.0 0.00087 18.8 0.0 1.5 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel LysR_substrate PF03466.20 EHU00812.1 - 3.9e-34 117.9 0.1 5.3e-34 117.4 0.1 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EHU00812.1 - 1.8e-11 43.8 0.0 2.9e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 EHU00812.1 - 0.00099 18.9 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain MarR_2 PF12802.7 EHU00812.1 - 0.072 13.0 0.1 0.21 11.5 0.1 1.8 1 0 0 1 1 1 0 MarR family HTH_8 PF02954.19 EHU00812.1 - 0.12 12.1 0.0 0.35 10.7 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family Fasciclin PF02469.22 EHU00813.1 - 5.2e-32 110.8 0.2 6.8e-32 110.4 0.2 1.1 1 0 0 1 1 1 1 Fasciclin domain Sigma70_r2 PF04542.14 EHU00814.1 - 4.2e-15 55.3 0.5 1.1e-14 53.9 0.3 1.8 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 EHU00814.1 - 5.5e-14 51.6 0.0 8.4e-14 51.0 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 EHU00814.1 - 4.3e-09 35.8 0.0 8.4e-09 34.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 EHU00814.1 - 0.0065 16.4 0.0 0.47 10.3 0.0 2.1 2 0 0 2 2 2 1 ECF sigma factor HTH_38 PF13936.6 EHU00814.1 - 0.014 15.1 0.0 0.055 13.2 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Terminase_5 PF06056.12 EHU00814.1 - 0.061 13.2 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_23 PF13384.6 EHU00814.1 - 0.088 12.6 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 Homeodomain-like domain RskA PF10099.9 EHU00815.1 - 1.1e-22 81.1 9.0 2.3e-22 80.2 9.0 1.5 1 1 0 1 1 1 1 Anti-sigma-K factor rskA MCPsignal PF00015.21 EHU00816.1 - 1.4e-50 171.5 31.0 1.4e-49 168.2 15.5 2.7 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 EHU00816.1 - 6.9e-06 26.4 6.3 1.3e-05 25.5 1.2 3.6 3 1 0 3 3 3 1 HAMP domain DUF948 PF06103.11 EHU00816.1 - 0.00017 21.8 23.5 0.014 15.7 0.6 5.7 3 2 2 5 5 5 3 Bacterial protein of unknown function (DUF948) Prominin PF05478.11 EHU00816.1 - 0.0037 15.3 10.1 0.012 13.6 3.2 2.4 1 1 1 2 2 2 2 Prominin Syntaxin-6_N PF09177.11 EHU00816.1 - 0.0059 17.1 11.3 0.036 14.6 2.9 3.8 3 1 0 3 3 3 1 Syntaxin 6, N-terminal Tweety PF04906.13 EHU00816.1 - 0.032 12.9 9.9 0.0098 14.6 2.1 2.4 2 0 0 2 2 2 0 Tweety DUF1664 PF07889.12 EHU00816.1 - 0.41 10.7 17.3 3.2 7.8 2.7 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) EcoEI_R_C PF08463.10 EHU00816.1 - 0.5 10.5 6.2 1.3 9.1 0.5 2.8 2 1 0 2 2 2 0 EcoEI R protein C-terminal SesA PF17107.5 EHU00816.1 - 1.2 9.3 8.2 1.3 9.2 3.8 3.1 2 2 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases TMPIT PF07851.13 EHU00816.1 - 1.3 8.2 7.9 0.79 8.9 2.1 2.4 2 0 0 2 2 2 0 TMPIT-like protein Mce4_CUP1 PF11887.8 EHU00816.1 - 5.8 6.3 11.5 6.2 6.2 1.4 2.7 2 1 1 3 3 3 0 Cholesterol uptake porter CUP1 of Mce4, putative 4HB_MCP_1 PF12729.7 EHU00816.1 - 6.2 6.3 20.7 0.52 9.8 0.8 4.9 2 2 1 4 4 4 0 Four helix bundle sensory module for signal transduction T7SS_ESX_EspC PF10824.8 EHU00816.1 - 6.7 7.3 30.0 0.35 11.4 7.7 4.4 2 2 2 4 4 4 0 Excreted virulence factor EspC, type VII ESX diderm K_trans PF02705.16 EHU00817.1 - 2.1e-199 663.5 23.9 2.4e-199 663.3 23.9 1.0 1 0 0 1 1 1 1 K+ potassium transporter PSS PF03034.15 EHU00817.1 - 0.0014 18.5 0.1 0.0063 16.3 0.0 2.1 2 0 0 2 2 2 1 Phosphatidyl serine synthase FMN_bind_2 PF04299.12 EHU00818.1 - 0.0039 16.9 0.0 0.0048 16.6 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain DDE_Tnp_IS66 PF03050.14 EHU00819.1 - 1.5e-22 80.4 0.0 1.7e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU00819.1 - 7e-17 61.4 0.1 1.5e-16 60.3 0.1 1.6 1 0 0 1 1 1 1 IS66 C-terminal element WGG PF10273.9 EHU00819.1 - 0.062 14.0 0.1 0.18 12.5 0.1 1.7 2 0 0 2 2 2 0 Pre-rRNA-processing protein TSR2 HTH_18 PF12833.7 EHU00820.1 - 1.3e-21 76.7 0.0 1.5e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 EHU00820.1 - 2.9e-14 52.7 0.0 2.6e-09 36.9 0.0 2.2 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Ribonuclease PF00545.20 EHU00821.1 - 3.1e-23 82.3 0.1 3.8e-23 82.0 0.1 1.1 1 0 0 1 1 1 1 ribonuclease Barstar PF01337.18 EHU00822.1 - 3.1e-12 46.3 0.6 3.6e-12 46.1 0.6 1.1 1 0 0 1 1 1 1 Barstar (barnase inhibitor) Virul_Fac PF10139.9 EHU00823.1 - 1.8e-135 453.3 1.3 2e-71 241.4 0.8 2.0 1 1 1 2 2 2 2 Putative bacterial virulence factor BenE PF03594.13 EHU00824.1 - 1.8e-124 415.4 44.8 2.2e-124 415.1 44.8 1.0 1 0 0 1 1 1 1 Benzoate membrane transport protein HTH_3 PF01381.22 EHU00825.1 - 5.5e-16 58.4 0.0 8.1e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EHU00825.1 - 7.5e-10 39.0 0.0 1.5e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Cupin_2 PF07883.11 EHU00825.1 - 2.4e-08 33.5 0.0 4.3e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Cupin domain HTH_19 PF12844.7 EHU00825.1 - 1.3e-05 25.1 0.0 2.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 EHU00825.1 - 3.2e-05 23.7 0.0 5.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Isochorismatase PF00857.20 EHU00826.1 - 3.7e-42 144.5 0.1 4e-42 144.3 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family PIN PF01850.21 EHU00828.1 - 0.032 14.8 0.0 0.032 14.7 0.0 1.1 1 0 0 1 1 1 0 PIN domain EIIC-GAT PF03611.14 EHU00830.1 - 2.1e-122 409.1 39.9 2.1e-122 409.1 39.9 1.4 2 0 0 2 2 2 1 PTS system sugar-specific permease component F_bP_aldolase PF01116.20 EHU00831.1 - 3.3e-88 295.8 0.7 3.7e-88 295.6 0.7 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II His_biosynth PF00977.21 EHU00831.1 - 0.021 14.3 0.1 0.043 13.3 0.1 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein Ribosomal_S15 PF00312.22 EHU00832.1 - 0.0075 16.5 1.5 0.016 15.4 1.3 1.8 1 1 0 1 1 1 1 Ribosomal protein S15 Plasmid_RAQPRD PF09686.10 EHU00832.1 - 0.059 13.6 2.1 0.11 12.8 2.1 1.4 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Fib_alpha PF08702.10 EHU00832.1 - 0.072 13.3 0.8 0.088 13.0 0.8 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family UspB PF10625.9 EHU00832.1 - 0.11 12.4 0.1 0.16 12.0 0.1 1.3 1 1 0 1 1 1 0 Universal stress protein B (UspB) PTS_EIIA_2 PF00359.22 EHU00833.1 - 9.2e-25 87.2 0.0 1.1e-24 87.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 AAA_33 PF13671.6 EHU00834.1 - 0.0004 20.6 0.0 0.0017 18.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EHU00834.1 - 0.00043 20.8 0.1 0.0051 17.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 EHU00834.1 - 0.011 16.1 0.0 0.018 15.3 0.0 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain CPT PF07931.12 EHU00834.1 - 0.012 15.4 0.0 0.043 13.7 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 EHU00834.1 - 0.048 12.9 0.0 0.088 12.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 EHU00834.1 - 0.061 13.7 0.1 0.091 13.1 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain KTI12 PF08433.10 EHU00834.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF393 PF04134.12 EHU00835.1 - 5.5e-20 72.8 1.9 6.3e-20 72.6 1.9 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF393 Med23 PF11573.8 EHU00836.1 - 0.0068 14.1 0.3 0.0068 14.1 0.3 1.3 2 0 0 2 2 2 1 Mediator complex subunit 23 DUF2231 PF09990.9 EHU00836.1 - 0.02 15.3 6.8 0.054 13.9 6.8 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2231) Strabismus PF06638.11 EHU00836.1 - 4.4 5.8 6.3 5.3 5.6 6.3 1.1 1 0 0 1 1 1 0 Strabismus protein GSDH PF07995.11 EHU00837.1 - 8.6e-18 64.7 0.1 5.9e-16 58.7 0.1 2.8 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase NHL PF01436.21 EHU00837.1 - 0.0002 21.2 1.8 0.34 11.0 0.0 3.0 3 0 0 3 3 3 2 NHL repeat Hexapep PF00132.24 EHU00838.1 - 6e-16 57.5 7.4 1.5e-09 37.2 5.4 3.5 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EHU00838.1 - 9.1e-08 31.7 3.8 9.1e-08 31.7 3.8 2.5 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase FAS_I_H PF18314.1 EHU00838.1 - 0.032 13.9 0.2 0.059 13.0 0.2 1.4 1 0 0 1 1 1 0 Fatty acid synthase type I helical domain Fucokinase PF07959.12 EHU00838.1 - 0.046 12.6 0.0 0.079 11.9 0.0 1.4 1 0 0 1 1 1 0 L-fucokinase Catalase PF00199.19 EHU00839.1 - 4e-186 618.7 0.3 5e-186 618.4 0.3 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EHU00839.1 - 1.4e-13 50.8 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Catalase-related immune-responsive ADH_N_2 PF16884.5 EHU00840.1 - 1.5e-42 143.9 0.0 3.4e-42 142.7 0.0 1.6 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 EHU00840.1 - 6.6e-19 68.2 0.0 1.1e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EHU00840.1 - 2.6e-11 44.7 0.0 4.3e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DAO PF01266.24 EHU00841.1 - 1.5e-17 64.3 0.8 1.8e-17 64.0 0.8 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EHU00841.1 - 0.066 12.3 0.3 0.11 11.5 0.0 1.4 2 0 0 2 2 2 0 FAD binding domain MethyltransfD12 PF02086.15 EHU00843.1 - 6.1e-27 94.9 0.0 7.1e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase PqqD PF05402.12 EHU00845.1 - 0.02 15.2 0.7 1.4 9.3 0.3 2.3 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) DUF4795 PF16043.5 EHU00845.1 - 0.061 12.9 0.0 0.086 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Caudo_TAP PF02413.17 EHU00846.1 - 2.8e-26 92.2 0.1 4e-26 91.7 0.1 1.2 1 0 0 1 1 1 1 Caudovirales tail fibre assembly protein, lambda gpK HTH_Tnp_1 PF01527.20 EHU00848.1 - 2.5e-07 30.9 0.0 3.5e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Transposase TnpB_IS66 PF05717.13 EHU00849.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHU00850.1 - 3.8e-97 325.1 4.2 1.6e-96 323.1 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU00850.1 - 6.9e-17 61.4 0.1 2.8e-16 59.5 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU00850.1 - 1.4e-14 54.2 1.5 3.5e-14 52.9 1.5 1.8 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU00850.1 - 8.8e-11 42.4 9.0 1.9e-10 41.4 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Phage_HK97_TLTM PF06120.11 EHU00850.1 - 0.011 15.0 0.8 0.021 14.0 0.8 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHU00850.1 - 0.02 15.2 4.2 0.085 13.2 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain UME PF08064.13 EHU00850.1 - 0.033 14.1 0.3 20 5.1 0.0 3.1 2 1 1 3 3 3 0 UME (NUC010) domain Exonuc_VII_L PF02601.15 EHU00850.1 - 0.04 13.5 2.7 0.04 13.5 1.0 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Troponin PF00992.20 EHU00850.1 - 0.044 14.1 2.8 0.078 13.3 2.8 1.3 1 0 0 1 1 1 0 Troponin FUSC PF04632.12 EHU00850.1 - 0.048 12.2 7.4 0.077 11.5 7.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tho2 PF11262.8 EHU00850.1 - 0.049 12.8 0.6 0.082 12.1 0.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FAM184 PF15665.5 EHU00850.1 - 0.052 13.3 8.0 0.082 12.7 8.0 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B HalX PF08663.10 EHU00850.1 - 0.13 12.6 2.4 0.34 11.2 2.4 1.7 1 0 0 1 1 1 0 HalX domain LXG PF04740.12 EHU00850.1 - 0.14 11.8 2.8 0.35 10.5 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHU00850.1 - 0.19 11.5 11.1 0.31 10.8 11.1 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DHR10 PF18595.1 EHU00850.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Zn-ribbon_8 PF09723.10 EHU00850.1 - 0.45 10.7 2.0 1 9.5 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF1192 PF06698.11 EHU00850.1 - 0.54 10.3 5.3 3.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHU00850.1 - 0.82 8.9 3.0 1.2 8.3 3.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHU00850.1 - 2 8.0 8.1 4.3 6.8 8.1 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHU00850.1 - 4.2 7.7 8.6 8.8 6.7 8.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CREPT PF16566.5 EHU00850.1 - 5.8 7.1 8.7 2.8 8.1 5.6 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour GFO_IDH_MocA_C PF02894.17 EHU00851.1 - 8.2e-09 35.5 0.0 8.3e-09 35.5 0.0 1.0 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DDE_Tnp_IS66 PF03050.14 EHU00852.1 - 2.8e-99 332.1 3.5 1.6e-98 329.7 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU00852.1 - 3.1e-16 59.3 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU00852.1 - 8e-15 55.0 1.3 1.9e-14 53.8 1.3 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU00852.1 - 1.7e-11 44.7 9.6 3.5e-11 43.7 9.6 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHU00852.1 - 0.017 14.9 6.4 0.027 14.3 6.4 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Phage_HK97_TLTM PF06120.11 EHU00852.1 - 0.021 14.0 1.7 0.042 13.0 1.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHU00852.1 - 0.022 15.1 4.3 0.091 13.1 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Exonuc_VII_L PF02601.15 EHU00852.1 - 0.028 14.0 1.8 0.039 13.5 0.6 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit FUSC PF04632.12 EHU00852.1 - 0.03 12.9 6.9 0.056 12.0 6.9 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tho2 PF11262.8 EHU00852.1 - 0.057 12.6 0.5 0.094 11.9 0.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Troponin PF00992.20 EHU00852.1 - 0.062 13.6 3.0 0.11 12.8 3.0 1.3 1 0 0 1 1 1 0 Troponin LXG PF04740.12 EHU00852.1 - 0.11 12.2 2.6 0.33 10.6 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHU00852.1 - 0.16 11.8 10.8 0.26 11.1 10.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family UME PF08064.13 EHU00852.1 - 0.16 11.9 0.5 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain HalX PF08663.10 EHU00852.1 - 0.23 11.8 3.1 0.59 10.5 3.1 1.7 1 0 0 1 1 1 0 HalX domain DHR10 PF18595.1 EHU00852.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF1192 PF06698.11 EHU00852.1 - 0.47 10.5 5.3 3.4 7.8 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHU00852.1 - 1.1 8.4 3.1 1.7 7.8 3.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHU00852.1 - 2.8 7.4 7.9 6.1 6.3 7.9 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHU00852.1 - 3.2 8.1 7.9 6.7 7.0 7.9 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 EHU00852.1 - 7.1 7.3 8.7 7.7 7.2 1.0 3.1 1 1 1 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHU00853.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHU00854.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU00854.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU00854.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU00854.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix DUF1330 PF07045.11 EHU00855.1 - 0.13 12.6 0.2 3.4 8.1 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1330) A_deaminase PF00962.22 EHU00856.1 - 2.7e-91 306.3 0.0 3.1e-91 306.1 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF945 PF06097.11 EHU00857.1 - 3.5e-128 428.6 23.6 3.9e-128 428.4 23.6 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF945) P5CR_dimer PF14748.6 EHU00857.1 - 0.01 16.1 0.3 0.026 14.8 0.3 1.6 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation PMI_typeI PF01238.21 EHU00858.1 - 1.7e-100 336.8 0.0 6.2e-100 335.0 0.0 1.7 1 1 1 2 2 2 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 EHU00858.1 - 5e-06 26.1 0.0 0.00045 19.9 0.0 2.4 2 0 0 2 2 2 1 Cupin domain AraC_binding_2 PF14525.6 EHU00858.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 AraC-binding-like domain AraC_binding PF02311.19 EHU00858.1 - 0.12 12.2 0.2 2.1 8.3 0.0 2.6 3 0 0 3 3 3 0 AraC-like ligand binding domain HutD PF05962.11 EHU00858.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 HutD MannoseP_isomer PF01050.18 EHU00858.1 - 0.18 11.7 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Lyase_1 PF00206.20 EHU00859.1 - 1.2e-122 409.2 0.1 1.6e-122 408.8 0.1 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 EHU00859.1 - 1.7e-25 89.2 0.3 5.6e-25 87.5 0.1 2.0 2 0 0 2 2 2 1 Fumarase C C-terminus G-alpha PF00503.20 EHU00859.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit DUF4288 PF14119.6 EHU00859.1 - 0.2 12.1 0.0 0.67 10.4 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) Ter PF05472.11 EHU00860.1 - 4.1e-131 436.4 5.5 4.6e-131 436.2 5.5 1.0 1 0 0 1 1 1 1 DNA replication terminus site-binding protein (Ter protein) DUF1878 PF08963.10 EHU00860.1 - 0.035 14.6 0.1 0.074 13.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1878) IFRD PF05004.13 EHU00860.1 - 0.07 12.2 0.7 0.58 9.2 0.3 2.2 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) zf-C4pol PF14260.6 EHU00860.1 - 0.14 12.7 0.4 0.54 10.8 0.3 2.1 1 1 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta PAP2 PF01569.21 EHU00861.1 - 3e-10 40.0 8.4 6.3e-10 38.9 8.4 1.6 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 EHU00861.1 - 0.00012 21.8 16.2 0.00063 19.5 16.2 1.9 1 1 0 1 1 1 1 PAP2 superfamily DUF2678 PF10856.8 EHU00861.1 - 0.078 12.9 1.8 0.75 9.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) RseC_MucC PF04246.12 EHU00861.1 - 0.33 10.9 7.6 0.073 13.0 1.1 2.2 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF2873 PF11395.8 EHU00861.1 - 4.5 7.2 11.5 0.11 12.4 4.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2873) UPF0014 PF03649.13 EHU00862.1 - 3.9e-76 255.6 21.9 4.7e-76 255.4 21.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) ABC_tran PF00005.27 EHU00863.1 - 5.8e-30 104.6 0.0 9.1e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EHU00863.1 - 3.6e-08 33.1 0.0 4.4e-07 29.6 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EHU00863.1 - 5.4e-07 29.3 0.1 1.1e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EHU00863.1 - 5.8e-07 30.0 0.3 8.4e-07 29.5 0.3 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EHU00863.1 - 1.3e-05 25.1 0.0 0.00035 20.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EHU00863.1 - 0.00015 21.7 0.0 0.00026 20.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase NACHT PF05729.12 EHU00863.1 - 0.00077 19.4 1.1 0.0077 16.2 0.0 2.4 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 EHU00863.1 - 0.00083 19.6 0.3 0.0036 17.6 0.3 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EHU00863.1 - 0.001 19.3 0.1 0.005 17.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 EHU00863.1 - 0.0015 18.0 0.0 0.0036 16.7 0.0 1.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_23 PF13476.6 EHU00863.1 - 0.0019 18.7 0.0 0.0023 18.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EHU00863.1 - 0.0023 18.5 0.0 0.0046 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 EHU00863.1 - 0.0025 17.7 0.2 0.019 14.9 0.0 1.9 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_30 PF13604.6 EHU00863.1 - 0.0049 16.6 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EHU00863.1 - 0.0056 16.3 0.1 0.014 15.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EHU00863.1 - 0.0076 16.4 0.0 0.014 15.5 0.0 1.6 2 0 0 2 2 1 1 AAA domain KAP_NTPase PF07693.14 EHU00863.1 - 0.0079 15.5 0.1 0.015 14.6 0.0 1.5 1 1 1 2 2 2 1 KAP family P-loop domain NTPase_1 PF03266.15 EHU00863.1 - 0.013 15.5 0.2 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 NTPase Mg_chelatase PF01078.21 EHU00863.1 - 0.02 14.3 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_15 PF13175.6 EHU00863.1 - 0.021 14.6 0.0 0.022 14.5 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 EHU00863.1 - 0.022 13.9 0.0 0.022 13.9 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit T2SSE PF00437.20 EHU00863.1 - 0.025 13.6 0.1 0.047 12.7 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_5 PF07728.14 EHU00863.1 - 0.027 14.5 0.1 0.19 11.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EHU00863.1 - 0.027 14.5 0.0 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EHU00863.1 - 0.038 14.0 0.1 0.07 13.1 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 EHU00863.1 - 0.042 14.3 0.1 0.39 11.1 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 EHU00863.1 - 0.051 13.8 0.1 2.2 8.6 0.1 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 EHU00863.1 - 0.052 14.0 0.0 0.12 12.8 0.0 1.6 2 0 0 2 2 1 0 RNA helicase MeaB PF03308.16 EHU00863.1 - 0.083 11.9 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 EHU00863.1 - 0.086 12.9 0.0 0.11 12.5 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase APS_kinase PF01583.20 EHU00863.1 - 0.097 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase Zeta_toxin PF06414.12 EHU00863.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 EHU00863.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family KTI12 PF08433.10 EHU00863.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ATPase_2 PF01637.18 EHU00863.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EHU00863.1 - 0.16 11.6 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 EHU00863.1 - 0.21 11.0 0.1 0.32 10.4 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein MFS_1 PF07690.16 EHU00864.1 - 5.4e-11 42.0 63.7 1.2e-09 37.6 55.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Collar PF07484.12 EHU00864.1 - 0.029 14.4 0.1 0.12 12.4 0.1 2.1 1 0 0 1 1 1 0 Phage Tail Collar Domain Rrf2 PF02082.20 EHU00865.1 - 5.3e-13 49.1 0.0 1e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator VirC2 PF07181.11 EHU00865.1 - 0.044 13.2 0.2 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 VirC2 protein DDE_Tnp_IS66 PF03050.14 EHU00866.1 - 1.1e-97 326.9 4.0 3.8e-97 325.1 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU00866.1 - 3.2e-16 59.2 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU00866.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU00866.1 - 1.2e-11 45.2 9.0 2.6e-11 44.1 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHU00866.1 - 0.017 14.9 6.4 0.027 14.3 6.4 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Phage_HK97_TLTM PF06120.11 EHU00866.1 - 0.022 14.0 1.7 0.042 13.0 1.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHU00866.1 - 0.022 15.1 4.3 0.091 13.1 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain FUSC PF04632.12 EHU00866.1 - 0.038 12.6 6.8 0.06 11.9 6.8 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 EHU00866.1 - 0.04 13.5 2.2 0.047 13.2 0.8 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Tho2 PF11262.8 EHU00866.1 - 0.057 12.6 0.5 0.094 11.9 0.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Troponin PF00992.20 EHU00866.1 - 0.062 13.6 3.0 0.11 12.8 3.0 1.3 1 0 0 1 1 1 0 Troponin LXG PF04740.12 EHU00866.1 - 0.11 12.3 2.5 0.32 10.7 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily UME PF08064.13 EHU00866.1 - 0.15 12.0 0.5 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain ERM PF00769.19 EHU00866.1 - 0.16 11.8 10.8 0.26 11.1 10.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HalX PF08663.10 EHU00866.1 - 0.23 11.8 3.1 0.59 10.5 3.1 1.7 1 0 0 1 1 1 0 HalX domain DHR10 PF18595.1 EHU00866.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Zn-ribbon_8 PF09723.10 EHU00866.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF1192 PF06698.11 EHU00866.1 - 0.53 10.4 5.3 3.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHU00866.1 - 1.1 8.4 3.1 1.7 7.8 3.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHU00866.1 - 2.8 7.4 7.9 6.1 6.3 7.9 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHU00866.1 - 3.3 8.1 7.9 6.7 7.0 7.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 EHU00866.1 - 7.2 7.3 8.7 7.7 7.2 1.0 3.0 1 1 1 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHU00867.1 - 7.4e-39 131.7 0.0 8.3e-39 131.6 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHU00868.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU00868.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU00868.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU00868.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix MethyltransfD12 PF02086.15 EHU00869.1 - 5.4e-13 49.2 0.0 6.2e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase ACR_tran PF00873.19 EHU00871.1 - 0 1136.1 8.5 0 1135.9 8.5 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 EHU00871.1 - 2.4e-11 43.2 35.4 1.3e-10 40.8 13.3 2.5 2 0 0 2 2 2 2 MMPL family SecD_SecF PF02355.16 EHU00871.1 - 0.00026 20.5 15.4 0.00026 20.5 15.4 2.3 2 0 0 2 2 2 1 Protein export membrane protein Patched PF02460.18 EHU00871.1 - 0.071 11.2 15.5 0.12 10.4 15.5 1.3 1 0 0 1 1 1 0 Patched family MASE5 PF17178.4 EHU00871.1 - 6.1 6.6 16.7 0.091 12.6 4.7 2.6 2 0 0 2 2 2 0 Membrane-associated sensor Biotin_lipoyl_2 PF13533.6 EHU00872.1 - 5.3e-19 67.8 0.0 6.4e-17 61.1 0.0 2.8 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_D23 PF16576.5 EHU00872.1 - 2.1e-16 59.8 1.6 3.8e-16 59.0 1.6 1.4 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 EHU00872.1 - 2.4e-11 44.3 0.2 8.4e-07 29.7 0.0 3.2 3 1 0 3 3 3 2 HlyD family secretion protein Biotin_lipoyl PF00364.22 EHU00872.1 - 0.0024 17.7 0.0 0.05 13.5 0.0 2.4 2 0 0 2 2 2 1 Biotin-requiring enzyme HlyD_2 PF12700.7 EHU00872.1 - 0.032 13.0 0.0 0.5 9.1 0.0 2.0 2 0 0 2 2 2 0 HlyD family secretion protein Acid_phosphat_B PF03767.14 EHU00872.1 - 0.044 13.4 0.1 0.081 12.5 0.1 1.4 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) TnpB_IS66 PF05717.13 EHU00873.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHU00874.1 - 7.6e-98 327.4 4.4 2.4e-97 325.8 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU00874.1 - 3.1e-16 59.3 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU00874.1 - 8.1e-15 54.9 1.3 1.9e-14 53.8 1.3 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU00874.1 - 1.6e-11 44.8 9.6 3.5e-11 43.7 9.6 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHU00874.1 - 0.017 14.9 6.4 0.027 14.3 6.4 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Csm1_N PF18504.1 EHU00874.1 - 0.022 15.1 4.3 0.091 13.1 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Phage_HK97_TLTM PF06120.11 EHU00874.1 - 0.023 13.9 1.7 0.042 13.0 1.7 1.3 1 0 0 1 1 1 0 Tail length tape measure protein Exonuc_VII_L PF02601.15 EHU00874.1 - 0.028 14.0 1.8 0.039 13.5 0.6 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit FUSC PF04632.12 EHU00874.1 - 0.031 12.8 6.9 0.056 12.0 6.9 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tho2 PF11262.8 EHU00874.1 - 0.056 12.6 0.5 0.094 11.9 0.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Troponin PF00992.20 EHU00874.1 - 0.062 13.6 3.0 0.11 12.8 3.0 1.3 1 0 0 1 1 1 0 Troponin UME PF08064.13 EHU00874.1 - 0.071 13.0 0.6 9.2 6.2 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain LXG PF04740.12 EHU00874.1 - 0.11 12.2 2.6 0.33 10.6 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHU00874.1 - 0.16 11.8 10.8 0.26 11.1 10.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HalX PF08663.10 EHU00874.1 - 0.23 11.8 3.1 0.59 10.5 3.1 1.7 1 0 0 1 1 1 0 HalX domain DHR10 PF18595.1 EHU00874.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF1192 PF06698.11 EHU00874.1 - 0.47 10.5 5.3 3.4 7.8 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHU00874.1 - 1.1 8.4 3.1 1.7 7.8 3.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHU00874.1 - 2.9 7.4 7.9 6.1 6.3 7.9 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHU00874.1 - 3.2 8.1 7.9 6.7 7.0 7.9 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 EHU00874.1 - 7.2 7.3 8.7 7.7 7.2 1.0 3.0 1 1 1 2 2 2 0 SlyX adh_short_C2 PF13561.6 EHU00876.1 - 2.8e-75 252.9 0.5 3.2e-75 252.7 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EHU00876.1 - 1.2e-59 201.1 1.3 1.4e-59 200.8 1.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EHU00876.1 - 3e-16 59.9 1.2 3.9e-16 59.5 1.2 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EHU00876.1 - 0.00015 21.7 1.4 0.00029 20.8 1.4 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EHU00876.1 - 0.00021 21.5 1.1 0.00035 20.8 1.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EHU00876.1 - 0.00054 20.0 0.2 0.00096 19.2 0.2 1.4 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 EHU00876.1 - 0.00078 19.0 0.4 0.026 14.0 0.3 2.5 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 EHU00876.1 - 0.0093 15.3 0.3 0.015 14.6 0.3 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EHU00876.1 - 0.034 14.6 0.8 0.062 13.8 0.8 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.16 EHU00876.1 - 0.1 12.2 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA CBM_48 PF02922.18 EHU00877.1 - 1.1e-19 70.6 0.0 2.4e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 EHU00877.1 - 1e-13 51.6 0.1 1.6e-07 31.2 0.0 3.1 2 1 1 3 3 3 3 Alpha amylase, catalytic domain Alpha-amylase PF00128.24 EHU00878.1 - 3.3e-21 76.2 0.0 6.1e-18 65.5 0.0 3.2 3 0 0 3 3 3 2 Alpha amylase, catalytic domain PilJ PF13675.6 EHU00878.1 - 1.8 8.6 5.2 8.5 6.4 0.7 2.9 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Alpha-amylase PF00128.24 EHU00879.1 - 2.9e-19 69.8 0.1 1.6e-12 47.6 0.0 3.0 1 1 1 2 2 2 2 Alpha amylase, catalytic domain DUF3459 PF11941.8 EHU00879.1 - 7.6e-12 45.4 0.1 1.9e-11 44.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) DUF1737 PF08410.10 EHU00879.1 - 0.14 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1737) Catalase PF00199.19 EHU00880.1 - 7.3e-177 588.2 0.0 9.1e-177 587.9 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EHU00880.1 - 9.4e-21 73.8 0.0 4.5e-20 71.6 0.0 2.2 2 0 0 2 2 2 1 Catalase-related immune-responsive Catalase_C PF18011.1 EHU00880.1 - 1.9e-18 66.6 0.0 2.9e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 EHU00880.1 - 0.0025 17.6 0.0 0.0043 16.9 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family DDE_Tnp_1_5 PF13737.6 EHU00881.1 - 1.2e-44 151.2 0.0 3.1e-44 149.9 0.0 1.7 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 EHU00881.1 - 1.9e-24 86.5 1.0 2.3e-24 86.2 1.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain Transthyretin PF00576.21 EHU00882.1 - 1.3e-35 122.4 0.1 1.5e-35 122.2 0.1 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family bMG3 PF11974.8 EHU00882.1 - 0.00018 21.5 0.0 0.00023 21.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial alpha-2-macroglobulin MG3 domain MG2 PF01835.19 EHU00882.1 - 0.00055 20.3 0.1 0.00072 20.0 0.1 1.2 1 0 0 1 1 1 1 MG2 domain Big_1 PF02369.16 EHU00882.1 - 0.013 15.5 0.0 0.025 14.6 0.0 1.5 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) CarboxypepD_reg PF13620.6 EHU00882.1 - 0.026 14.8 0.1 0.046 14.0 0.1 1.4 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain MliC PF09864.9 EHU00883.1 - 1.6e-16 60.0 0.0 2e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Membrane-bound lysozyme-inhibitor of c-type lysozyme LPAM_1 PF08139.12 EHU00883.1 - 0.36 11.4 0.8 0.36 11.4 0.8 1.7 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site Putative_PNPOx PF01243.20 EHU00884.1 - 2.2e-23 82.2 0.0 3.4e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 EHU00884.1 - 1.7e-19 69.6 3.5 2.5e-19 69.1 1.6 2.2 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region ThuA PF06283.11 EHU00884.1 - 0.086 13.0 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Trehalose utilisation tRNA-synt_1b PF00579.25 EHU00885.1 - 1.6e-91 306.6 0.0 2.2e-91 306.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 EHU00885.1 - 5.5e-06 26.0 0.0 1.1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 EHU00885.1 - 0.0038 17.0 0.0 0.0093 15.8 0.0 1.6 1 0 0 1 1 1 1 S4 domain Phos_pyr_kin PF08543.12 EHU00886.1 - 2.1e-15 56.8 0.0 2.7e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EHU00886.1 - 3.5e-09 36.4 0.0 2.4e-08 33.7 0.0 2.1 1 1 0 2 2 2 1 pfkB family carbohydrate kinase SsgA PF04686.12 EHU00886.1 - 0.1 12.6 0.1 0.4 10.7 0.1 2.1 2 1 0 2 2 2 0 Streptomyces sporulation and cell division protein, SsgA PIN PF01850.21 EHU00886.1 - 0.16 12.4 0.0 0.44 11.1 0.0 1.7 2 0 0 2 2 2 0 PIN domain GST_C PF00043.25 EHU00887.1 - 4.8e-12 45.9 0.1 7.4e-12 45.3 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EHU00887.1 - 1.4e-10 41.3 0.0 2.9e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EHU00887.1 - 1.7e-09 37.9 0.0 4.8e-09 36.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EHU00887.1 - 2.1e-09 37.3 0.3 3.4e-09 36.6 0.3 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EHU00887.1 - 3.5e-09 36.8 0.0 8.9e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EHU00887.1 - 6.1e-07 29.6 0.1 9.4e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_5 PF18485.1 EHU00887.1 - 7.5e-05 23.0 0.1 0.00032 21.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 EHU00887.1 - 0.036 14.4 0.0 0.056 13.7 0.0 1.4 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 EHU00887.1 - 0.095 12.5 0.0 0.43 10.4 0.0 2.0 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain PTR2 PF00854.21 EHU00888.1 - 3.1e-87 293.0 22.4 4.5e-87 292.4 22.4 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 EHU00888.1 - 8.1e-18 64.5 47.7 8.1e-18 64.5 47.7 2.6 1 1 0 2 2 2 1 Major Facilitator Superfamily GATase PF00117.28 EHU00889.1 - 3.2e-12 46.6 0.0 5e-12 46.0 0.0 1.2 1 1 0 1 1 1 1 Glutamine amidotransferase class-I HhH-GPD PF00730.25 EHU00890.1 - 2e-19 70.0 0.0 3e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EHU00890.1 - 2.1e-07 30.5 0.0 4.4e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 EHU00890.1 - 0.00019 21.7 3.4 0.00031 21.0 3.4 1.4 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III Rnf-Nqr PF02508.14 EHU00891.1 - 1.3e-59 201.0 12.5 1.5e-59 200.9 12.5 1.0 1 0 0 1 1 1 1 Rnf-Nqr subunit, membrane protein FMN_bind PF04205.14 EHU00892.1 - 1.6e-18 67.0 0.1 3.5e-18 65.9 0.1 1.5 1 0 0 1 1 1 1 FMN-binding domain Wzz PF02706.15 EHU00892.1 - 0.15 12.4 0.1 0.25 11.7 0.1 1.4 1 0 0 1 1 1 0 Chain length determinant protein NQR2_RnfD_RnfE PF03116.15 EHU00893.1 - 8e-106 353.7 15.7 9e-106 353.5 15.7 1.0 1 0 0 1 1 1 1 NQR2, RnfD, RnfE family Complex1_51K PF01512.17 EHU00894.1 - 3.1e-49 166.7 0.0 1.8e-48 164.2 0.0 2.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit RnfC_N PF13375.6 EHU00894.1 - 4.6e-31 106.8 0.0 1.2e-30 105.4 0.0 1.8 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Fer4_7 PF12838.7 EHU00894.1 - 1.1e-09 38.8 7.7 3.2e-09 37.2 7.7 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain SLBB PF10531.9 EHU00894.1 - 2.1e-09 37.1 0.1 4.9e-09 35.9 0.1 1.7 1 0 0 1 1 1 1 SLBB domain Fer4_10 PF13237.6 EHU00894.1 - 2.4e-09 37.2 9.2 6.5e-09 35.8 9.2 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 EHU00894.1 - 1.1e-07 31.4 14.0 0.00084 19.1 1.5 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 EHU00894.1 - 8.5e-07 29.3 7.9 8.5e-07 29.3 7.9 3.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 EHU00894.1 - 1.2e-06 29.0 10.9 1.7e-05 25.2 10.0 3.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EHU00894.1 - 5e-06 26.6 11.4 1.8e-05 24.8 10.7 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 EHU00894.1 - 1.1e-05 25.2 15.2 0.014 15.4 4.6 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 EHU00894.1 - 1.7e-05 24.9 11.3 0.016 15.7 1.7 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 EHU00894.1 - 0.00024 21.0 16.4 0.0094 16.0 3.2 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 EHU00894.1 - 0.00067 19.7 9.4 0.0027 17.8 9.3 2.1 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_3 PF12798.7 EHU00894.1 - 0.0024 18.7 15.8 0.052 14.5 4.1 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.6 EHU00894.1 - 0.0037 17.4 10.6 0.22 11.7 0.8 3.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 EHU00894.1 - 0.0062 17.5 22.4 0.011 16.6 0.4 4.7 3 2 0 3 3 2 2 4Fe-4S double cluster binding domain Fer4_22 PF17179.4 EHU00894.1 - 0.0097 16.7 9.0 0.11 13.4 0.8 3.4 2 1 0 2 2 2 1 4Fe-4S dicluster domain NQRA_SLBB PF11973.8 EHU00894.1 - 0.039 14.6 0.0 0.079 13.6 0.0 1.5 1 0 0 1 1 1 0 NQRA C-terminal domain Fer4_13 PF13370.6 EHU00894.1 - 0.21 12.2 0.1 0.21 12.2 0.1 6.1 6 2 0 6 6 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_21 PF14697.6 EHU00895.1 - 2.6e-17 62.7 15.4 2.6e-17 62.7 15.4 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain FeS PF04060.13 EHU00895.1 - 1.7e-11 43.6 5.3 1.7e-11 43.6 5.3 2.1 2 0 0 2 2 1 1 Putative Fe-S cluster Fer4 PF00037.27 EHU00895.1 - 1.9e-11 43.3 26.4 6e-08 32.2 5.9 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_7 PF12838.7 EHU00895.1 - 2.7e-08 34.3 16.9 0.0011 19.5 8.2 2.8 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EHU00895.1 - 4.2e-08 33.2 32.7 4.2e-06 26.8 15.1 2.6 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.7 EHU00895.1 - 1.7e-07 30.9 20.8 5.8e-06 26.1 3.0 3.3 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_10 PF13237.6 EHU00895.1 - 2.2e-06 27.6 14.3 2.2e-06 27.6 14.3 3.1 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 EHU00895.1 - 4.6e-06 26.5 4.7 4.6e-06 26.5 4.7 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_16 PF13484.6 EHU00895.1 - 4.9e-06 27.4 19.7 0.00027 21.8 2.8 3.0 3 0 0 3 3 3 2 4Fe-4S double cluster binding domain Fer4_3 PF12798.7 EHU00895.1 - 0.0067 17.3 4.7 0.0067 17.3 4.7 3.4 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_4 PF12800.7 EHU00895.1 - 0.017 15.6 25.4 0.048 14.2 3.7 3.4 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_22 PF17179.4 EHU00895.1 - 0.029 15.2 0.7 0.029 15.2 0.7 2.6 3 0 0 3 3 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 EHU00895.1 - 0.035 14.7 4.6 0.035 14.7 4.6 3.2 3 1 1 4 4 3 0 4Fe-4S single cluster domain of Ferredoxin I EpuA PF11772.8 EHU00895.1 - 0.13 12.0 1.0 0.22 11.2 1.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta DUF1290 PF06947.12 EHU00895.1 - 0.2 11.7 0.3 1.2 9.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1290) Fer4_17 PF13534.6 EHU00895.1 - 0.24 12.0 21.6 0.73 10.4 2.6 3.0 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 EHU00895.1 - 0.56 11.0 19.3 0.14 12.9 4.3 3.6 1 1 1 2 2 2 0 4Fe-4S single cluster domain Fer4_18 PF13746.6 EHU00895.1 - 2 8.6 16.1 1.8 8.8 3.6 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 EHU00895.1 - 2.6 8.6 23.0 0.11 12.9 2.4 2.9 1 1 3 4 4 3 0 4Fe-4S dicluster domain Rnf-Nqr PF02508.14 EHU00896.1 - 1.2e-58 198.0 22.4 1.3e-58 197.8 22.4 1.0 1 0 0 1 1 1 1 Rnf-Nqr subunit, membrane protein DUF2569 PF10754.9 EHU00897.1 - 1.3e-41 142.4 14.0 1.5e-41 142.2 14.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2569) TctA PF01970.16 EHU00897.1 - 0.053 12.2 5.0 0.065 11.9 5.0 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family DUF2070 PF09843.9 EHU00897.1 - 0.27 9.5 9.3 0.31 9.3 9.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) HTH_24 PF13412.6 EHU00898.1 - 1.8e-18 65.8 0.2 3.3e-18 65.0 0.2 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 EHU00898.1 - 1.1e-15 57.1 0.6 3.5e-15 55.6 0.6 1.8 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.21 EHU00898.1 - 1.4e-14 53.8 0.0 2e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain MarR PF01047.22 EHU00898.1 - 1.3e-05 25.0 0.0 2.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 EHU00898.1 - 0.0011 18.8 0.1 0.0021 17.9 0.1 1.4 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 EHU00898.1 - 0.0014 18.6 0.1 0.0026 17.8 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 EHU00898.1 - 0.01 15.9 0.5 0.02 15.0 0.2 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_47 PF16221.5 EHU00898.1 - 0.04 13.5 0.0 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 winged helix-turn-helix HTH_IclR PF09339.10 EHU00898.1 - 0.042 13.6 0.1 0.091 12.6 0.1 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain Rrf2 PF02082.20 EHU00898.1 - 0.093 13.1 0.0 0.33 11.3 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator Aminotran_3 PF00202.21 EHU00899.1 - 2.3e-75 253.8 0.0 2.8e-75 253.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III APH PF01636.23 EHU00900.1 - 1.6e-28 100.3 3.4 1.8e-28 100.1 1.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family HAD_2 PF13419.6 EHU00901.1 - 3e-09 37.2 0.0 1.3e-08 35.1 0.0 1.8 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EHU00901.1 - 0.00034 21.0 0.0 0.0049 17.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase CSD PF00313.22 EHU00902.1 - 1.2e-08 34.7 0.1 2.3e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain DUF2058 PF09831.9 EHU00904.1 - 1.8e-57 194.3 11.5 2e-57 194.1 11.5 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2058) Pfg27 PF09216.10 EHU00904.1 - 0.0056 16.5 0.2 0.012 15.4 0.0 1.5 1 1 0 1 1 1 1 Pfg27 EMC3_TMCO1 PF01956.16 EHU00904.1 - 0.05 13.3 5.7 0.069 12.9 5.7 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like PseudoU_synth_2 PF00849.22 EHU00905.1 - 4.6e-28 98.3 0.0 7e-28 97.7 0.0 1.3 1 1 0 1 1 1 1 RNA pseudouridylate synthase LPAM_1 PF08139.12 EHU00906.1 - 4.2 8.0 5.6 0.42 11.2 1.0 1.9 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site CheZ PF04344.13 EHU00907.1 - 6e-53 179.8 0.1 6.9e-53 179.6 0.1 1.0 1 0 0 1 1 1 1 Chemotaxis phosphatase, CheZ PYC_OADA PF02436.18 EHU00907.1 - 0.0084 15.9 0.3 0.023 14.4 0.0 1.7 2 0 0 2 2 2 1 Conserved carboxylase domain HSBP1 PF06825.12 EHU00907.1 - 0.35 10.8 2.6 0.22 11.4 0.5 1.8 2 0 0 2 2 2 0 Heat shock factor binding protein 1 MCPsignal PF00015.21 EHU00908.1 - 9e-47 159.1 18.6 9e-47 159.1 18.6 3.2 3 1 1 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.7 EHU00908.1 - 6.1e-14 52.0 0.5 6.1e-14 52.0 0.5 3.0 3 1 0 3 3 3 1 Four helix bundle sensory module for signal transduction Oxidored_q6 PF01058.22 EHU00908.1 - 0.21 11.4 4.2 0.56 10.0 0.5 2.7 2 1 0 2 2 2 0 NADH ubiquinone oxidoreductase, 20 Kd subunit DUF4200 PF13863.6 EHU00908.1 - 0.72 10.3 5.9 0.16 12.4 1.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Snapin_Pallidin PF14712.6 EHU00908.1 - 3.5 8.1 11.3 5.8 7.4 0.2 3.7 3 1 1 4 4 4 0 Snapin/Pallidin Transp_cyt_pur PF02133.15 EHU00909.1 - 2.5e-45 155.1 43.9 8.4e-45 153.3 43.9 1.7 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF4760 PF15956.5 EHU00910.1 - 0.036 14.2 1.3 0.045 13.9 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4760) MCPsignal PF00015.21 EHU00911.1 - 1e-47 162.2 14.2 1e-47 162.2 14.2 3.8 3 1 1 4 4 4 3 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 EHU00911.1 - 1.4e-05 25.4 7.3 2.1e-05 24.8 0.4 4.3 3 1 2 5 5 4 1 HAMP domain DUF948 PF06103.11 EHU00911.1 - 0.0058 16.9 31.4 0.0085 16.3 3.5 5.9 4 2 2 6 6 6 3 Bacterial protein of unknown function (DUF948) EcoEI_R_C PF08463.10 EHU00911.1 - 0.079 13.1 0.3 0.079 13.1 0.3 2.5 3 1 0 3 3 3 0 EcoEI R protein C-terminal DUF2096 PF09869.9 EHU00911.1 - 0.14 12.3 1.3 0.4 10.7 0.4 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2096) DUF1664 PF07889.12 EHU00911.1 - 0.22 11.6 17.9 1.9 8.6 3.1 3.8 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Sec8_exocyst PF04048.14 EHU00911.1 - 0.26 11.1 16.5 3.2 7.6 1.8 4.0 2 2 1 3 3 3 0 Sec8 exocyst complex component specific domain Syntaxin-6_N PF09177.11 EHU00911.1 - 0.46 11.1 21.4 0.054 14.0 5.7 4.6 3 2 1 4 4 4 0 Syntaxin 6, N-terminal TssO PF17561.2 EHU00911.1 - 0.86 9.7 4.7 1.7 8.7 0.2 3.1 3 0 0 3 3 3 0 Type VI secretion system, TssO ISG65-75 PF11727.8 EHU00911.1 - 1.3 8.2 15.5 0.031 13.5 3.4 2.6 3 0 0 3 3 3 0 Invariant surface glycoprotein T7SS_ESX_EspC PF10824.8 EHU00911.1 - 2 8.9 29.3 1.4 9.4 4.0 4.7 3 2 2 5 5 5 0 Excreted virulence factor EspC, type VII ESX diderm Tweety PF04906.13 EHU00911.1 - 2.1 7.0 11.4 0.19 10.3 4.2 2.4 2 1 0 2 2 2 0 Tweety Laminin_II PF06009.12 EHU00911.1 - 3.1 7.8 29.6 0.087 12.8 3.0 4.0 4 1 1 5 5 5 0 Laminin Domain II Fib_alpha PF08702.10 EHU00911.1 - 4 7.6 14.6 6.1 7.0 0.4 4.2 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family TMPIT PF07851.13 EHU00911.1 - 6 6.0 10.6 1.3 8.2 1.7 2.7 3 0 0 3 3 3 0 TMPIT-like protein CHAP PF05257.16 EHU00912.1 - 0.017 15.7 0.1 0.03 14.9 0.1 1.5 1 0 0 1 1 1 0 CHAP domain MFS_1 PF07690.16 EHU00913.1 - 3.7e-39 134.7 63.2 5.6e-31 107.7 36.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EHU00913.1 - 2.6e-10 39.3 21.0 1.3e-07 30.5 4.2 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector Peripla_BP_3 PF13377.6 EHU00914.1 - 7.4e-17 62.2 0.3 1.9e-15 57.6 0.1 2.2 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 EHU00914.1 - 4.1e-13 49.4 0.0 5.7e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 EHU00914.1 - 2.7e-06 27.1 1.1 6.7e-06 25.8 0.4 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 EHU00914.1 - 0.00031 20.4 0.0 0.00051 19.7 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein domain HTH_31 PF13560.6 EHU00914.1 - 0.024 15.0 0.0 0.063 13.6 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_3 PF01381.22 EHU00914.1 - 0.026 14.6 0.0 0.057 13.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix HTH_IclR PF09339.10 EHU00914.1 - 0.084 12.7 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain GFO_IDH_MocA PF01408.22 EHU00915.1 - 3.8e-30 105.2 0.3 7.7e-30 104.2 0.3 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EHU00915.1 - 8.8e-12 45.1 0.3 1.7e-11 44.2 0.3 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 EHU00915.1 - 0.0007 20.2 0.1 0.0013 19.4 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain CoA_binding PF02629.19 EHU00915.1 - 0.0011 19.5 0.1 0.0025 18.4 0.1 1.6 1 0 0 1 1 1 1 CoA binding domain F420_oxidored PF03807.17 EHU00915.1 - 0.0021 18.6 0.0 0.0057 17.2 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA_C PF02894.17 EHU00916.1 - 4.5e-06 26.6 0.1 7.8e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.22 EHU00916.1 - 6.4e-06 27.0 0.0 2.4e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold MFS_2 PF13347.6 EHU00917.1 - 6.8e-07 28.2 3.6 7.9e-07 28.0 3.6 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 EHU00917.1 - 0.011 14.7 5.0 0.028 13.4 4.9 1.5 1 1 0 1 1 1 0 Major Facilitator Superfamily MFS_2 PF13347.6 EHU00918.1 - 3.9e-28 98.2 23.6 5.1e-28 97.8 23.6 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein YbjM PF11045.8 EHU00918.1 - 0.015 15.4 0.0 0.015 15.4 0.0 3.2 3 1 0 3 3 3 0 Putative inner membrane protein of Enterobacteriaceae PepSY_TM PF03929.16 EHU00918.1 - 0.055 13.1 0.5 3.1 7.4 0.0 2.7 2 1 1 3 3 3 0 PepSY-associated TM region Orf78 PF06024.12 EHU00918.1 - 8.1 6.8 6.3 1.3 9.3 0.0 2.8 4 0 0 4 4 4 0 Orf78 (ac78) Molybdopterin PF00384.22 EHU00920.1 - 0.0018 17.3 0.0 0.0025 16.9 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molybdopterin PF00384.22 EHU00921.1 - 9.7e-19 67.6 0.0 2e-18 66.6 0.0 1.4 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 EHU00921.1 - 4e-11 42.9 0.1 9.6e-11 41.7 0.1 1.7 1 1 0 1 1 1 1 Molydopterin dinucleotide binding domain TPP_enzyme_M PF00205.22 EHU00921.1 - 0.078 12.7 0.0 6.2 6.6 0.0 2.8 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, central domain KGG PF10685.9 EHU00923.1 - 2.6e-17 62.5 9.7 6.3e-09 35.8 3.8 2.1 2 0 0 2 2 2 2 Stress-induced bacterial acidophilic repeat motif KGG PF10685.9 EHU00927.1 - 1.5e-19 69.6 17.4 6.6e-10 38.9 4.4 2.1 2 0 0 2 2 2 2 Stress-induced bacterial acidophilic repeat motif Meth_synt_2 PF01717.18 EHU00928.1 - 2.6e-36 125.6 0.0 6e-36 124.3 0.0 1.5 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain CNP1 PF08750.11 EHU00928.1 - 0.00048 20.1 0.0 0.00085 19.3 0.0 1.3 1 0 0 1 1 1 1 CNP1-like family Meth_synt_1 PF08267.12 EHU00928.1 - 0.0038 16.8 0.1 0.026 14.0 0.0 2.2 2 1 0 2 2 2 1 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 EHU00928.1 - 0.0042 16.3 0.0 0.013 14.7 0.0 1.6 1 1 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) DUF1852 PF08908.11 EHU00929.1 - 5.1e-184 610.6 4.6 5.8e-184 610.5 4.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1852) HlyD_2 PF12700.7 EHU00929.1 - 0.038 12.7 0.2 0.054 12.2 0.2 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Cupin_6 PF12852.7 EHU00930.1 - 3.2e-35 121.5 3.9 4.3e-35 121.1 3.9 1.2 1 0 0 1 1 1 1 Cupin HTH_18 PF12833.7 EHU00930.1 - 1.4e-18 66.9 0.1 3.4e-18 65.7 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 EHU00930.1 - 1e-17 63.7 0.0 3.5e-10 39.7 0.0 2.5 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Cupin_2 PF07883.11 EHU00930.1 - 6.7e-05 22.5 0.0 0.00016 21.3 0.0 1.6 1 0 0 1 1 1 1 Cupin domain TetR_N PF00440.23 EHU00930.1 - 0.0039 17.0 0.1 0.0085 15.9 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family AraC_binding PF02311.19 EHU00930.1 - 0.02 14.8 0.0 0.053 13.4 0.0 1.7 1 0 0 1 1 1 0 AraC-like ligand binding domain HTH_IclR PF09339.10 EHU00930.1 - 0.069 13.0 0.1 0.79 9.6 0.0 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain DUF2917 PF11142.8 EHU00930.1 - 0.089 12.2 0.0 0.24 10.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2917) Epimerase PF01370.21 EHU00931.1 - 2.2e-13 50.2 0.2 1.1e-12 47.9 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EHU00931.1 - 4.9e-13 49.4 0.2 1.2e-12 48.1 0.1 1.6 1 1 1 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EHU00931.1 - 3.1e-08 33.5 0.1 5.1e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 EHU00931.1 - 6e-07 28.8 0.0 1.1e-06 28.0 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 EHU00931.1 - 2.4e-06 26.8 0.0 3.4e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EHU00931.1 - 1.6e-05 24.5 0.1 3.8e-05 23.3 0.1 1.6 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 EHU00931.1 - 0.00055 20.2 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_4 PF07993.12 EHU00931.1 - 0.006 15.8 0.0 0.015 14.4 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein KR PF08659.10 EHU00931.1 - 0.012 15.6 0.1 0.022 14.7 0.1 1.5 1 0 0 1 1 1 0 KR domain ApbA PF02558.16 EHU00931.1 - 0.013 15.2 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA adh_short PF00106.25 EHU00931.1 - 0.013 15.0 0.0 0.025 14.0 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase F420_oxidored PF03807.17 EHU00931.1 - 0.017 15.7 0.0 0.04 14.5 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EHU00931.1 - 0.028 14.6 0.0 0.049 13.8 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Lactamase_B PF00753.27 EHU00932.1 - 1.2e-23 84.2 2.8 1.4e-23 83.9 2.8 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EHU00932.1 - 0.0002 21.0 1.9 0.0003 20.3 1.6 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EHU00932.1 - 0.024 14.5 0.1 0.044 13.7 0.1 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain dCMP_cyt_deam_1 PF00383.23 EHU00933.1 - 7.8e-13 48.2 0.1 1e-12 47.8 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EHU00933.1 - 0.00029 20.6 0.0 0.00038 20.2 0.0 1.3 1 1 0 1 1 1 1 MafB19-like deaminase GTA_holin_3TM PF11351.8 EHU00934.1 - 0.0084 16.6 0.6 0.0084 16.6 0.6 2.3 1 1 1 2 2 2 1 Holin of 3TMs, for gene-transfer release Miff PF05644.11 EHU00934.1 - 0.015 14.9 2.7 0.034 13.8 2.6 1.6 1 1 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Arabinose_Isome PF02610.15 EHU00935.1 - 8.9e-171 567.9 0.0 1.1e-170 567.7 0.0 1.1 1 0 0 1 1 1 1 L-arabinose isomerase Arabinose_Iso_C PF11762.8 EHU00935.1 - 3.3e-45 152.6 0.0 6.2e-45 151.7 0.0 1.5 1 0 0 1 1 1 1 L-arabinose isomerase C-terminal domain FGGY_C PF02782.16 EHU00936.1 - 2.2e-37 128.7 0.2 3.2e-37 128.2 0.2 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EHU00936.1 - 1.2e-11 44.6 0.0 5.7e-11 42.5 0.0 2.0 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain HSP70 PF00012.20 EHU00936.1 - 0.0016 16.7 0.0 0.0021 16.3 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein Peripla_BP_1 PF00532.21 EHU00937.1 - 4.2e-91 305.2 0.0 4.9e-91 305.0 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 EHU00937.1 - 5e-21 75.4 1.2 6.2e-21 75.1 1.2 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain ABC_tran PF00005.27 EHU00938.1 - 4.3e-51 173.0 0.0 8.3e-30 104.1 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EHU00938.1 - 2e-15 57.4 0.1 0.0006 19.7 0.0 3.2 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EHU00938.1 - 4.7e-05 23.3 0.3 0.00053 19.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EHU00938.1 - 0.0018 18.0 0.1 0.0049 16.6 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain TsaE PF02367.17 EHU00938.1 - 0.0092 16.0 0.4 6 6.9 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE SMC_N PF02463.19 EHU00938.1 - 0.01 15.3 0.0 0.13 11.6 0.0 2.3 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EHU00938.1 - 0.016 15.7 0.1 0.03 14.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EHU00938.1 - 0.022 14.5 0.5 0.73 9.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain GAD PF02938.14 EHU00938.1 - 0.035 14.4 0.0 0.075 13.3 0.0 1.6 1 0 0 1 1 1 0 GAD domain MMR_HSR1 PF01926.23 EHU00938.1 - 0.066 13.3 0.3 0.76 9.9 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_15 PF13175.6 EHU00938.1 - 0.08 12.6 0.1 0.45 10.2 0.0 2.2 3 0 0 3 3 3 0 AAA ATPase domain AAA_27 PF13514.6 EHU00938.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EHU00938.1 - 0.31 11.3 4.1 1.9 8.7 0.1 3.2 3 0 0 3 3 3 0 AAA domain BPD_transp_2 PF02653.16 EHU00939.1 - 1.7e-42 145.4 38.1 1.7e-42 145.4 38.1 1.4 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component PDR_CDR PF06422.12 EHU00939.1 - 0.024 14.5 0.5 0.024 14.5 0.5 2.6 3 0 0 3 3 3 0 CDR ABC transporter Phage_holin_2_1 PF04971.12 EHU00939.1 - 0.1 12.6 2.5 0.55 10.3 1.9 2.6 2 0 0 2 2 2 0 Bacteriophage P21 holin S AraC_binding PF02311.19 EHU00940.1 - 2.8e-24 85.6 0.1 4.3e-24 85.0 0.1 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain HTH_18 PF12833.7 EHU00940.1 - 7.5e-21 74.2 1.3 1.9e-20 72.9 0.2 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 EHU00940.1 - 5e-19 67.9 0.0 6.8e-10 38.8 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Cupin_2 PF07883.11 EHU00940.1 - 0.034 13.9 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 Cupin domain GFO_IDH_MocA PF01408.22 EHU00941.1 - 0.0012 19.7 0.0 0.0013 19.6 0.0 1.0 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EHU00942.1 - 1.1e-12 48.0 0.0 1.3e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.22 EHU00942.1 - 0.024 15.5 0.0 0.034 15.0 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DDE_Tnp_IS66 PF03050.14 EHU00943.1 - 2.1e-70 237.4 0.0 2.4e-70 237.2 0.0 1.0 1 0 0 1 1 1 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU00943.1 - 2e-16 59.9 0.1 5.2e-16 58.6 0.1 1.8 1 0 0 1 1 1 1 IS66 C-terminal element TnpB_IS66 PF05717.13 EHU00944.1 - 1e-34 118.5 0.0 1.1e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHU00945.1 - 3e-98 328.8 3.4 1.9e-97 326.1 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU00945.1 - 3.4e-16 59.2 0.1 1.3e-15 57.3 0.1 2.1 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU00945.1 - 1.4e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU00945.1 - 8.7e-11 42.4 9.0 1.9e-10 41.4 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Phage_HK97_TLTM PF06120.11 EHU00945.1 - 0.029 13.6 0.7 0.056 12.6 0.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein UME PF08064.13 EHU00945.1 - 0.038 13.9 0.4 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain Exonuc_VII_L PF02601.15 EHU00945.1 - 0.041 13.4 2.5 0.044 13.4 0.9 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit FUSC PF04632.12 EHU00945.1 - 0.063 11.8 7.7 0.1 11.1 7.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Csm1_N PF18504.1 EHU00945.1 - 0.13 12.7 3.4 0.86 10.0 0.2 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Tho2 PF11262.8 EHU00945.1 - 0.17 11.0 0.3 0.28 10.4 0.3 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DHR10 PF18595.1 EHU00945.1 - 0.18 11.9 10.2 0.31 11.1 10.2 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain ERM PF00769.19 EHU00945.1 - 0.28 11.0 10.4 0.45 10.3 10.4 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family LXG PF04740.12 EHU00945.1 - 0.28 10.9 2.4 0.86 9.3 0.3 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily HHH_8 PF14716.6 EHU00945.1 - 0.34 11.3 4.0 0.56 10.6 1.9 2.4 2 1 0 2 2 2 0 Helix-hairpin-helix domain Zn-ribbon_8 PF09723.10 EHU00945.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain TSNAXIP1_N PF15739.5 EHU00945.1 - 0.46 10.9 3.2 0.99 9.8 3.2 1.5 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus FAM184 PF15665.5 EHU00945.1 - 0.49 10.1 7.3 0.78 9.5 7.3 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B TMPIT PF07851.13 EHU00945.1 - 0.77 8.9 2.7 1.2 8.4 2.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein CREPT PF16566.5 EHU00945.1 - 2.3 8.4 8.3 1.1 9.5 5.2 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour HAUS-augmin3 PF14932.6 EHU00945.1 - 2.5 7.6 7.4 5.8 6.4 7.4 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 SlyX PF04102.12 EHU00945.1 - 8.1 7.2 8.7 17 6.1 2.1 3.0 1 1 1 2 2 2 0 SlyX GFO_IDH_MocA PF01408.22 EHU00946.1 - 7.1e-14 52.7 0.0 1.2e-13 52.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Dala_Dala_lig_C PF07478.13 EHU00947.1 - 2.2e-05 24.1 0.0 6.3e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.6 EHU00947.1 - 7.6e-05 22.4 0.0 0.00025 20.7 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 EHU00947.1 - 0.00018 21.1 0.0 0.00032 20.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 EHU00947.1 - 0.0018 17.8 0.0 0.0054 16.3 0.0 1.8 2 1 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 EHU00947.1 - 0.0036 17.4 0.0 0.0052 16.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain RmlD_sub_bind PF04321.17 EHU00948.1 - 3.2e-97 325.1 0.0 3.6e-97 324.9 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EHU00948.1 - 3.6e-20 72.5 0.1 7.3e-20 71.4 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EHU00948.1 - 9.9e-17 61.3 0.0 1.3e-16 60.9 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EHU00948.1 - 1.8e-12 47.0 0.3 2.3e-11 43.4 0.3 2.6 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EHU00948.1 - 2.5e-06 26.8 0.0 1.7e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein dTDP_sugar_isom PF00908.17 EHU00949.1 - 2.3e-72 242.1 0.0 2.6e-72 242.0 0.0 1.0 1 0 0 1 1 1 1 dTDP-4-dehydrorhamnose 3,5-epimerase NTP_transferase PF00483.23 EHU00950.1 - 1.3e-65 221.4 0.0 1.5e-65 221.2 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EHU00950.1 - 3e-10 40.7 0.0 3.7e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain HNH_2 PF13391.6 EHU00951.1 - 3.8e-05 23.7 0.1 0.00019 21.5 0.1 2.1 1 1 0 1 1 1 1 HNH endonuclease Sigma70_r4 PF04545.16 EHU00952.1 - 4.2e-19 67.8 4.0 4.3e-17 61.4 0.7 2.4 2 0 0 2 2 2 2 Sigma-70, region 4 Sigma70_r2 PF04542.14 EHU00952.1 - 1.3e-16 60.1 3.1 2.4e-16 59.2 0.4 2.3 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r3 PF04539.16 EHU00952.1 - 9.6e-15 54.4 1.3 1.7e-14 53.6 0.7 1.7 2 0 0 2 2 2 1 Sigma-70 region 3 Sigma70_r4_2 PF08281.12 EHU00952.1 - 1.3e-10 40.8 3.1 1.5e-09 37.4 1.0 2.5 2 0 0 2 2 2 1 Sigma-70, region 4 Sacchrp_dh_C PF16653.5 EHU00952.1 - 0.0095 16.1 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain UPF0122 PF04297.14 EHU00952.1 - 0.034 14.4 0.2 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like GerE PF00196.19 EHU00952.1 - 0.046 13.3 0.3 0.73 9.4 0.1 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family zf-C4H2 PF10146.9 EHU00952.1 - 0.3 11.4 2.7 0.37 11.1 2.7 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein Phage_int_SAM_1 PF02899.17 EHU00953.1 - 2.6e-08 34.0 0.0 7.4e-08 32.6 0.0 1.8 1 1 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain zf-C2HC5 PF06221.13 EHU00953.1 - 0.013 15.5 0.1 2.2 8.3 0.0 2.3 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-AN1 PF01428.16 EHU00953.1 - 0.027 14.7 4.6 0.06 13.5 0.6 2.4 2 0 0 2 2 2 0 AN1-like Zinc finger zf-BED PF02892.15 EHU00953.1 - 0.035 14.1 0.6 0.61 10.2 0.0 2.3 2 0 0 2 2 2 0 BED zinc finger FYVE PF01363.21 EHU00953.1 - 0.036 14.2 0.2 0.98 9.6 0.0 2.2 2 0 0 2 2 2 0 FYVE zinc finger RecR PF02132.15 EHU00953.1 - 0.046 13.3 0.7 0.93 9.1 0.0 2.3 2 0 0 2 2 2 0 RecR protein zf-ribbon_3 PF13248.6 EHU00953.1 - 0.12 11.9 0.2 0.12 11.9 0.2 1.9 2 0 0 2 2 2 0 zinc-ribbon domain PALP PF00291.25 EHU00954.1 - 1e-51 176.1 0.2 1.2e-51 175.9 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SBP_bac_3 PF00497.20 EHU00955.1 - 1.1e-72 244.1 0.5 1.5e-72 243.7 0.5 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 EHU00955.1 - 4.5e-10 39.7 0.1 1.2e-09 38.4 0.1 1.7 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site NMT1 PF09084.11 EHU00955.1 - 0.00025 21.1 0.4 0.0027 17.7 0.0 2.2 1 1 0 2 2 2 1 NMT1/THI5 like Phosphonate-bd PF12974.7 EHU00955.1 - 0.057 13.0 1.8 2.6 7.5 0.4 3.3 2 1 0 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein COX6C PF02937.15 EHU00955.1 - 0.4 10.8 1.4 7 6.9 0.1 2.7 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VIc BPD_transp_1 PF00528.22 EHU00956.1 - 3e-23 82.5 12.6 3.8e-23 82.2 12.6 1.1 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 EHU00957.1 - 2.2e-34 118.9 0.0 3.2e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EHU00957.1 - 8e-13 48.9 0.0 6.2e-06 26.2 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EHU00957.1 - 5.1e-09 35.9 0.0 1.7e-08 34.1 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EHU00957.1 - 1.1e-06 29.0 0.1 7.9e-06 26.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EHU00957.1 - 2.4e-05 24.0 0.0 4.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EHU00957.1 - 0.00013 22.4 0.9 0.00057 20.3 0.9 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EHU00957.1 - 0.00015 22.3 0.1 0.00032 21.2 0.1 1.4 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EHU00957.1 - 0.00016 21.7 0.0 0.0016 18.4 0.0 2.0 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea ABC_ATPase PF09818.9 EHU00957.1 - 0.0002 20.3 0.2 0.54 9.0 0.0 2.8 2 1 0 2 2 2 2 Predicted ATPase of the ABC class AAA_13 PF13166.6 EHU00957.1 - 0.00025 19.8 0.0 0.046 12.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 EHU00957.1 - 0.00049 19.9 0.0 0.19 11.4 0.1 2.1 1 1 1 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 EHU00957.1 - 0.0039 17.4 0.2 0.016 15.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 EHU00957.1 - 0.0049 16.8 0.0 0.0099 15.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 EHU00957.1 - 0.0065 16.2 0.1 0.014 15.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 EHU00957.1 - 0.0089 15.1 0.2 0.02 14.0 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 EHU00957.1 - 0.011 15.7 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA PF00004.29 EHU00957.1 - 0.011 16.1 0.1 0.77 10.2 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 EHU00957.1 - 0.013 15.1 0.1 0.027 14.1 0.0 1.6 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 EHU00957.1 - 0.015 15.0 0.0 0.035 13.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EHU00957.1 - 0.015 15.8 0.0 0.026 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EHU00957.1 - 0.015 14.5 0.0 0.041 13.1 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain MobB PF03205.14 EHU00957.1 - 0.017 15.0 0.0 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.6 EHU00957.1 - 0.019 15.2 0.1 0.053 13.8 0.0 1.9 2 1 0 2 2 2 0 AAA domain TniB PF05621.11 EHU00957.1 - 0.028 13.8 0.0 4 6.8 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein AAA_25 PF13481.6 EHU00957.1 - 0.034 13.7 0.3 0.34 10.5 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EHU00957.1 - 0.051 13.6 0.0 0.33 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EHU00957.1 - 0.074 13.3 0.1 1.1 9.5 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Pox_A32 PF04665.12 EHU00957.1 - 0.084 12.3 0.0 0.43 10.0 0.0 1.9 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_19 PF13245.6 EHU00957.1 - 0.095 13.0 0.1 0.28 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 EHU00957.1 - 0.097 12.4 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family PduV-EutP PF10662.9 EHU00957.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 EHU00957.1 - 0.15 12.1 0.3 0.39 10.8 0.2 1.7 2 1 0 2 2 1 0 50S ribosome-binding GTPase Rad17 PF03215.15 EHU00957.1 - 0.19 11.7 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain G-alpha PF00503.20 EHU00957.1 - 0.19 10.8 0.0 0.37 9.9 0.0 1.3 1 1 0 1 1 1 0 G-protein alpha subunit Acyl_transf_3 PF01757.22 EHU00958.1 - 1.3e-16 60.6 45.7 2.3e-16 59.8 45.8 1.4 1 1 0 1 1 1 1 Acyltransferase family Phage_integrase PF00589.22 EHU00959.1 - 1.1e-20 74.1 0.2 2.5e-20 72.9 0.0 1.6 2 0 0 2 2 2 1 Phage integrase family Arm-DNA-bind_3 PF13356.6 EHU00959.1 - 6.3e-20 71.3 0.1 1.4e-19 70.2 0.1 1.7 1 0 0 1 1 1 1 Arm DNA-binding domain Phage_int_SAM_3 PF14659.6 EHU00959.1 - 0.0028 17.9 0.1 0.0086 16.3 0.1 1.9 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain YchF-GTPase_C PF06071.13 EHU00960.1 - 1.3e-39 134.3 0.3 2.6e-39 133.3 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EHU00960.1 - 7.3e-22 77.6 0.0 1.5e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EHU00960.1 - 6.8e-09 35.4 0.0 3.1e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B TGS PF02824.21 EHU00960.1 - 0.0062 16.6 0.2 0.22 11.6 0.1 2.7 2 1 0 2 2 2 1 TGS domain AAA_18 PF13238.6 EHU00960.1 - 0.076 13.6 0.1 0.64 10.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain Pept_tRNA_hydro PF01195.19 EHU00961.1 - 3.9e-56 189.7 0.0 4.6e-56 189.4 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase DUF2583 PF10762.9 EHU00962.1 - 9.8e-41 138.1 0.2 1.1e-40 137.9 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2583) SdpI PF13630.6 EHU00962.1 - 0.057 13.6 1.5 0.077 13.1 1.5 1.3 1 0 0 1 1 1 0 SdpI/YhfL protein family Fig1 PF12351.8 EHU00962.1 - 0.083 12.8 0.6 0.1 12.5 0.6 1.0 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 PIRT PF15099.6 EHU00962.1 - 0.22 11.1 0.4 0.28 10.8 0.2 1.4 1 1 0 1 1 1 0 Phosphoinositide-interacting protein family GGDEF PF00990.21 EHU00963.1 - 1.1e-37 129.3 0.0 1.5e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain MTABC_N PF16185.5 EHU00963.1 - 1.3 8.5 12.2 0.02 14.4 2.3 2.0 2 0 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region DUF872 PF05915.12 EHU00963.1 - 2.6 8.2 11.0 0.4 10.8 3.4 2.8 1 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) SRTM1 PF15872.5 EHU00963.1 - 8.9 6.5 7.9 7.2 6.8 0.0 2.7 3 0 0 3 3 3 0 Serine-rich and transmembrane domain-containing protein 1 Pribosyltran_N PF13793.6 EHU00964.1 - 1.3e-50 170.2 0.2 2e-49 166.4 0.0 2.6 2 1 1 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EHU00964.1 - 1.8e-30 106.3 0.4 3.3e-30 105.5 0.4 1.5 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EHU00964.1 - 1.9e-19 69.7 2.3 2.5e-19 69.3 0.6 2.0 3 0 0 3 3 3 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EHU00964.1 - 0.00061 19.3 0.0 0.00093 18.7 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 EHU00964.1 - 0.065 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase GHMP_kinases_N PF00288.26 EHU00965.1 - 2.5e-11 43.6 0.0 4.4e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EHU00965.1 - 2.1e-06 28.0 0.0 4.8e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal LolB PF03550.14 EHU00966.1 - 4.9e-44 150.1 3.9 6.3e-44 149.7 3.9 1.1 1 0 0 1 1 1 1 Outer membrane lipoprotein LolB DUF4292 PF14125.6 EHU00966.1 - 0.0068 16.1 0.1 0.0081 15.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4292) DUF5110 PF17137.4 EHU00966.1 - 0.02 15.1 0.1 0.069 13.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5110) TOH_N PF12549.8 EHU00966.1 - 0.09 12.7 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 Tyrosine hydroxylase N terminal RHS_repeat PF05593.14 EHU00966.1 - 0.11 13.1 0.7 0.62 10.6 0.0 2.4 2 1 0 2 2 2 0 RHS Repeat GlutR_N PF05201.15 EHU00967.1 - 8.3e-53 178.1 0.0 1.8e-52 177.0 0.0 1.6 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.20 EHU00967.1 - 1.2e-48 164.7 0.7 2.3e-48 163.8 0.7 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.20 EHU00967.1 - 3.1e-23 82.0 2.8 3.7e-23 81.8 0.4 2.4 2 0 0 2 2 2 1 Glutamyl-tRNAGlu reductase, dimerisation domain F420_oxidored PF03807.17 EHU00967.1 - 5.9e-05 23.6 3.9 7.8e-05 23.2 1.4 2.6 3 1 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 EHU00967.1 - 0.00049 19.1 0.4 0.001 18.1 0.4 1.5 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Sacchrp_dh_NADP PF03435.18 EHU00967.1 - 0.0023 18.2 0.3 0.0065 16.7 0.3 2.0 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GFO_IDH_MocA PF01408.22 EHU00967.1 - 0.016 16.0 0.3 0.28 12.0 0.0 2.6 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_7 PF13241.6 EHU00967.1 - 0.08 13.4 0.1 0.26 11.7 0.1 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding PCRF PF03462.18 EHU00968.1 - 1.2e-75 253.6 1.1 1.6e-75 253.2 0.2 1.6 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 EHU00968.1 - 5.7e-41 139.1 0.1 5.7e-41 139.1 0.1 2.1 3 0 0 3 3 3 1 RF-1 domain ABC_tran_CTD PF16326.5 EHU00968.1 - 0.00089 19.5 0.3 0.00089 19.5 0.3 2.7 2 1 1 3 3 3 1 ABC transporter C-terminal domain dUTPase_2 PF08761.11 EHU00968.1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 dUTPase Methyltransf_31 PF13847.6 EHU00969.1 - 7.4e-21 74.5 0.0 1.1e-20 74.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmC_N PF17827.1 EHU00969.1 - 6.6e-18 65.1 1.7 9.8e-18 64.5 0.1 2.2 3 0 0 3 3 1 1 PrmC N-terminal domain MTS PF05175.14 EHU00969.1 - 6.7e-17 61.5 0.0 2.6e-16 59.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EHU00969.1 - 4.9e-10 40.0 0.0 1.1e-09 38.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EHU00969.1 - 7.8e-10 38.8 0.0 4.9e-09 36.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 EHU00969.1 - 7.8e-08 32.2 0.0 1.6e-07 31.2 0.0 1.4 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 PrmA PF06325.13 EHU00969.1 - 1.3e-07 31.4 0.0 1.9e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EHU00969.1 - 2e-06 28.3 0.0 5.5e-06 27.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EHU00969.1 - 1e-05 25.1 0.0 1.8e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Cons_hypoth95 PF03602.15 EHU00969.1 - 1.4e-05 24.8 0.0 3.8e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_12 PF08242.12 EHU00969.1 - 1.7e-05 25.4 0.0 7.8e-05 23.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EHU00969.1 - 0.00011 22.1 0.0 0.00016 21.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 EHU00969.1 - 0.00052 19.8 0.0 0.00078 19.2 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_2 PF00891.18 EHU00969.1 - 0.00055 19.3 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain N6_Mtase PF02384.16 EHU00969.1 - 0.00081 18.7 0.0 0.0011 18.3 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase Bunya_G2 PF03563.13 EHU00969.1 - 0.026 13.8 0.0 0.039 13.2 0.0 1.1 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 ADH_zinc_N PF00107.26 EHU00969.1 - 0.048 13.6 0.0 0.082 12.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase GidB PF02527.15 EHU00969.1 - 0.056 12.8 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G CMAS PF02353.20 EHU00969.1 - 0.12 11.6 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Eco57I PF07669.11 EHU00969.1 - 0.15 12.5 0.0 0.42 11.1 0.0 1.7 2 0 0 2 2 1 0 Eco57I restriction-modification methylase Methyltransf_18 PF12847.7 EHU00969.1 - 0.19 11.7 0.0 0.8 9.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 EHU00969.1 - 0.23 10.8 0.0 0.35 10.2 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family SirB PF04247.12 EHU00970.1 - 2.7e-41 140.4 6.0 3.1e-41 140.2 6.0 1.0 1 0 0 1 1 1 1 Invasion gene expression up-regulator, SirB DUF1516 PF07457.11 EHU00970.1 - 0.014 15.6 2.6 0.022 14.9 2.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1516) Transglut_core2 PF13369.6 EHU00971.1 - 8.1e-42 142.4 0.0 1.1e-41 142.0 0.0 1.2 1 0 0 1 1 1 1 Transglutaminase-like superfamily TPR_9 PF13371.6 EHU00971.1 - 2.4e-24 85.2 0.1 4.4e-24 84.4 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat DAHP_synth_1 PF00793.20 EHU00972.1 - 4e-69 232.5 0.0 4.6e-69 232.3 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family GFO_IDH_MocA PF01408.22 EHU00972.1 - 0.071 13.9 0.0 0.13 13.1 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Na_Ca_ex PF01699.24 EHU00973.1 - 2.9e-23 82.5 34.7 1.2e-12 48.0 15.9 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein ChaB PF06150.12 EHU00974.1 - 1.1e-27 96.4 4.0 1.3e-27 96.1 4.0 1.1 1 0 0 1 1 1 1 ChaB NTS PF15447.6 EHU00974.1 - 0.036 14.6 0.0 0.07 13.6 0.0 1.5 1 0 0 1 1 1 0 N-terminal segments of PfEMP1 FAM25 PF15825.5 EHU00974.1 - 0.048 14.0 0.0 0.06 13.7 0.0 1.1 1 0 0 1 1 1 0 FAM25 family Sigma70_r2 PF04542.14 EHU00974.1 - 0.11 12.3 0.1 0.15 11.8 0.1 1.4 1 1 0 1 1 1 0 Sigma-70 region 2 ChaC PF04752.12 EHU00975.1 - 1.5e-48 165.2 0.0 1.8e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein Pkinase PF00069.25 EHU00976.1 - 3.2e-24 85.7 0.0 7.1e-24 84.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EHU00976.1 - 1e-11 44.6 0.0 3.7e-11 42.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EHU00976.1 - 0.0009 19.2 0.1 0.0065 16.4 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EHU00976.1 - 0.0074 15.1 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase PP2C_2 PF13672.6 EHU00978.1 - 4.9e-10 39.4 1.1 7e-10 38.9 1.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EHU00978.1 - 0.0015 18.5 0.2 0.01 15.7 0.2 2.2 1 1 1 2 2 2 1 Stage II sporulation protein E (SpoIIE) FHA PF00498.26 EHU00979.1 - 3.9e-09 36.7 0.2 8.7e-09 35.6 0.1 1.7 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 EHU00979.1 - 7.1e-05 23.1 0.0 0.00014 22.1 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain TagF_N PF09867.9 EHU00980.1 - 3.6e-45 153.3 0.5 4.8e-45 152.9 0.5 1.2 1 0 0 1 1 1 1 TagF N-terminal domain, Type VI secretion system-associated ImcF-related_N PF14331.6 EHU00981.1 - 1.5e-91 306.4 1.3 1.5e-91 306.4 1.3 2.1 3 0 0 3 3 3 1 ImcF-related N-terminal domain IcmF-related PF06761.12 EHU00981.1 - 1.4e-28 100.3 6.6 1.4e-28 100.3 6.6 2.1 2 0 0 2 2 2 1 Intracellular multiplication and human macrophage-killing DotU PF09850.9 EHU00982.1 - 5.8e-65 218.8 0.8 2.1e-64 217.1 0.6 1.9 2 0 0 2 2 2 1 Type VI secretion system protein DotU OmpA PF00691.20 EHU00982.1 - 5.5e-06 26.7 0.0 9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 OmpA family NIT PF08376.10 EHU00983.1 - 4.4e-46 158.2 9.1 4.4e-46 158.2 9.1 2.3 2 0 0 2 2 2 1 Nitrate and nitrite sensing ANTAR PF03861.14 EHU00983.1 - 1.6e-19 69.5 1.3 4.9e-19 67.9 1.3 1.9 1 0 0 1 1 1 1 ANTAR domain DUF4287 PF14117.6 EHU00983.1 - 2.1 8.6 4.3 1.4 9.1 0.6 2.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4287) NMT1_2 PF13379.6 EHU00984.1 - 6.2e-104 347.2 1.5 7.9e-104 346.8 1.5 1.1 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 EHU00984.1 - 0.019 14.9 0.0 0.37 10.7 0.0 2.3 2 1 0 2 2 2 0 NMT1/THI5 like DUF4158 PF13700.6 EHU00984.1 - 0.091 12.6 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) TAT_signal PF10518.9 EHU00984.1 - 0.14 12.1 0.1 0.14 12.1 0.1 1.9 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence BPD_transp_1 PF00528.22 EHU00985.1 - 3.1e-20 72.7 16.8 3.1e-20 72.7 16.8 2.0 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 EHU00986.1 - 1e-33 116.7 0.0 1.6e-33 116.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EHU00986.1 - 2.5e-05 24.2 0.0 5.7e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 EHU00986.1 - 6.3e-05 22.9 0.0 0.35 10.6 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EHU00986.1 - 7.4e-05 23.2 0.0 0.00012 22.5 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EHU00986.1 - 0.00063 19.4 0.1 0.0013 18.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 EHU00986.1 - 0.0011 19.3 0.1 0.013 15.9 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EHU00986.1 - 0.0059 16.8 0.0 0.022 14.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EHU00986.1 - 0.016 15.7 0.1 0.029 14.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EHU00986.1 - 0.033 14.2 0.4 0.093 12.8 0.1 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_5 PF07728.14 EHU00986.1 - 0.034 14.1 0.4 0.26 11.3 0.0 2.3 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 EHU00986.1 - 0.045 13.7 0.1 1.4 8.8 0.1 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain SbcCD_C PF13558.6 EHU00986.1 - 0.048 13.9 0.1 0.49 10.7 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 EHU00986.1 - 0.069 13.4 1.2 0.31 11.3 1.2 2.3 1 1 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 EHU00986.1 - 0.081 11.7 1.5 0.16 10.8 0.0 2.0 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_15 PF13175.6 EHU00986.1 - 0.16 11.6 0.0 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain ATP-synt_ab PF00006.25 EHU00986.1 - 0.2 11.3 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Pyr_redox_2 PF07992.14 EHU00987.1 - 2.3e-97 325.8 0.5 5.5e-48 163.7 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EHU00987.1 - 2.8e-36 123.9 3.5 3.7e-16 59.4 0.0 5.2 5 1 0 5 5 4 2 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 EHU00987.1 - 1e-28 99.3 0.0 2.8e-28 97.9 0.0 1.8 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rubredoxin_C PF18267.1 EHU00987.1 - 3e-24 84.7 0.0 3.7e-11 42.8 0.0 2.7 2 0 0 2 2 2 2 Rubredoxin NAD+ reductase C-terminal domain NIR_SIR PF01077.22 EHU00987.1 - 2.8e-21 75.7 0.0 5e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_3 PF13738.6 EHU00987.1 - 3.7e-17 62.5 0.0 1.3e-10 41.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 EHU00987.1 - 4.2e-13 49.4 12.4 8.9e-08 32.4 10.0 2.7 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain NIR_SIR_ferr PF03460.17 EHU00987.1 - 3.7e-12 45.9 0.0 9e-12 44.7 0.0 1.7 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain K_oxygenase PF13434.6 EHU00987.1 - 5.2e-08 32.4 0.1 0.031 13.4 0.0 4.4 4 1 1 5 5 5 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 EHU00987.1 - 7.5e-07 28.2 7.4 1.3 7.6 0.5 6.2 6 1 1 7 7 7 3 HI0933-like protein NAD_binding_8 PF13450.6 EHU00987.1 - 9.3e-07 29.0 2.9 0.25 11.6 0.1 3.9 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EHU00987.1 - 3.5e-06 26.4 5.6 0.036 13.1 0.4 3.5 3 1 1 4 4 4 2 Glucose inhibited division protein A NAD_binding_7 PF13241.6 EHU00987.1 - 4.9e-05 23.7 1.6 5 7.6 0.2 4.1 4 0 0 4 4 4 2 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 EHU00987.1 - 0.00013 21.4 6.7 0.039 13.2 0.4 3.2 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 EHU00987.1 - 0.00031 19.9 20.7 0.13 11.3 0.7 5.1 4 1 0 5 5 5 3 FAD binding domain FAD_oxidored PF12831.7 EHU00987.1 - 0.00047 19.6 3.7 0.017 14.5 0.7 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EHU00987.1 - 0.0013 18.1 4.7 0.43 9.8 0.5 2.4 2 0 0 2 2 2 2 FAD binding domain 3HCDH_N PF02737.18 EHU00987.1 - 0.004 17.1 1.2 1.2 9.0 0.1 2.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 EHU00987.1 - 0.0065 16.5 20.7 0.8 9.7 0.1 7.1 4 4 4 8 8 8 1 FAD-NAD(P)-binding DAO PF01266.24 EHU00987.1 - 0.028 14.0 15.6 0.58 9.7 1.9 5.2 4 2 2 6 6 6 0 FAD dependent oxidoreductase TrkA_N PF02254.18 EHU00987.1 - 0.038 14.2 3.4 15 5.8 0.1 4.2 4 0 0 4 4 4 0 TrkA-N domain LpxI_N PF17930.1 EHU00987.1 - 0.068 13.1 1.6 8.2 6.3 0.2 2.6 2 0 0 2 2 2 0 LpxI N-terminal domain Trp_halogenase PF04820.14 EHU00987.1 - 1.2 7.8 3.4 7.2 5.3 0.2 2.9 3 0 0 3 3 3 0 Tryptophan halogenase Molybdopterin PF00384.22 EHU00988.1 - 6.6e-75 252.7 0.0 9.1e-75 252.2 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 EHU00988.1 - 2.5e-25 88.7 0.0 5.2e-25 87.6 0.0 1.6 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 EHU00988.1 - 7e-17 61.2 1.9 7e-17 61.2 1.9 2.3 3 0 0 3 3 3 1 Molybdopterin oxidoreductase Fe4S4 domain Fer2_BFD PF04324.15 EHU00988.1 - 7.9e-11 42.1 2.0 1.9e-10 40.9 2.0 1.7 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain McyA_C PF12593.8 EHU00988.1 - 0.022 14.5 0.1 0.072 12.9 0.1 1.8 1 0 0 1 1 1 0 Microcystin synthetase C terminal TP_methylase PF00590.20 EHU00989.1 - 1.2e-47 162.7 0.4 1.4e-47 162.4 0.4 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases MuF_C PF18819.1 EHU00989.1 - 0.23 11.5 0.0 2.9 7.9 0.0 2.1 2 0 0 2 2 2 0 Phage MuF-C-terminal domain DeoRC PF00455.22 EHU00990.1 - 1.1e-42 145.7 0.8 1.2e-42 145.5 0.2 1.4 2 0 0 2 2 2 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 EHU00990.1 - 3.9e-16 58.5 0.7 7.4e-16 57.6 0.7 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 EHU00990.1 - 2.3e-06 27.5 0.1 5.4e-06 26.3 0.1 1.7 1 0 0 1 1 1 1 HTH domain HTH_24 PF13412.6 EHU00990.1 - 7.4e-06 25.4 0.1 4.1e-05 23.0 0.0 2.4 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding GntR PF00392.21 EHU00990.1 - 7e-05 22.4 0.3 0.00018 21.1 0.3 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 EHU00990.1 - 7.1e-05 22.8 0.1 0.00022 21.2 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_5 PF01022.20 EHU00990.1 - 0.00021 21.1 0.0 0.00038 20.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR PF01047.22 EHU00990.1 - 0.00026 20.8 0.1 0.001 19.0 0.1 2.0 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 EHU00990.1 - 0.012 16.0 0.0 0.035 14.4 0.0 1.8 1 1 0 1 1 1 0 Transcriptional regulator MarR_2 PF12802.7 EHU00990.1 - 0.017 15.0 0.3 0.082 12.8 0.1 2.2 3 0 0 3 3 3 0 MarR family HTH_IclR PF09339.10 EHU00990.1 - 0.018 14.8 0.1 0.047 13.5 0.1 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain Penicillinase_R PF03965.16 EHU00990.1 - 0.026 14.9 0.2 0.055 13.8 0.2 1.5 1 0 0 1 1 1 0 Penicillinase repressor FaeA PF04703.12 EHU00990.1 - 0.039 14.3 0.3 0.33 11.4 0.0 2.4 2 0 0 2 2 2 0 FaeA-like protein HTH_AsnC-type PF13404.6 EHU00990.1 - 0.046 13.6 0.1 0.49 10.3 0.0 2.7 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain PaaX PF07848.12 EHU00990.1 - 0.057 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 PaaX-like protein HTH_Mga PF08280.11 EHU00990.1 - 0.087 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain IF-2B PF01008.17 EHU00990.1 - 0.11 11.7 0.8 0.34 10.1 0.1 2.0 2 0 0 2 2 2 0 Initiation factor 2 subunit family DUF977 PF06163.11 EHU00990.1 - 0.12 12.4 0.2 0.16 11.9 0.2 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) adh_short_C2 PF13561.6 EHU00991.1 - 8.3e-62 208.8 0.1 1e-61 208.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EHU00991.1 - 1.3e-48 165.0 0.1 1.6e-48 164.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EHU00991.1 - 4.4e-13 49.5 0.1 6.6e-13 49.0 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EHU00991.1 - 0.00013 21.5 0.0 0.042 13.3 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EHU00991.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Peripla_BP_4 PF13407.6 EHU00992.1 - 1.7e-51 175.3 12.2 2.4e-51 174.8 12.2 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 EHU00992.1 - 5.5e-18 65.4 2.0 6.9e-18 65.1 2.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 EHU00992.1 - 4.5e-06 27.1 0.2 2.5e-05 24.7 0.1 1.9 2 0 0 2 2 2 1 Periplasmic binding protein-like domain PucR PF07905.11 EHU00992.1 - 0.00041 20.6 0.0 0.00085 19.6 0.0 1.5 1 0 0 1 1 1 1 Purine catabolism regulatory protein-like family LpxI_N PF17930.1 EHU00992.1 - 0.0085 16.0 1.7 0.029 14.2 0.5 2.2 2 0 0 2 2 2 1 LpxI N-terminal domain TPP_enzyme_N PF02776.18 EHU00992.1 - 0.065 12.8 0.2 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain DNA_circ_N PF07157.12 EHU00992.1 - 0.074 13.5 0.0 0.24 11.8 0.0 1.8 1 0 0 1 1 1 0 DNA circularisation protein N-terminus Asparaginase_C PF17763.1 EHU00992.1 - 0.25 11.6 1.7 3.5 7.9 0.1 2.6 2 0 0 2 2 2 0 Glutaminase/Asparaginase C-terminal domain DUF2291 PF10054.9 EHU00993.1 - 3.6e-52 177.0 0.0 4.1e-52 176.8 0.0 1.0 1 0 0 1 1 1 1 Predicted periplasmic lipoprotein (DUF2291) ABC_tran PF00005.27 EHU00994.1 - 1.1e-51 174.9 0.1 2.6e-28 99.3 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EHU00994.1 - 1.5e-11 44.7 1.6 0.0027 17.6 0.1 3.2 2 1 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EHU00994.1 - 6e-05 22.9 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 EHU00994.1 - 0.00018 21.0 3.2 0.0022 17.5 1.2 2.8 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EHU00994.1 - 0.00073 19.5 0.1 0.0054 16.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase TsaE PF02367.17 EHU00994.1 - 0.0018 18.2 0.2 1.8 8.6 0.1 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 EHU00994.1 - 0.0036 17.6 3.8 0.52 10.6 0.0 3.3 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.6 EHU00994.1 - 0.0036 17.0 0.0 0.01 15.6 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 EHU00994.1 - 0.0046 16.7 0.1 0.025 14.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EHU00994.1 - 0.005 17.4 0.0 0.017 15.7 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_13 PF13166.6 EHU00994.1 - 0.0067 15.1 0.1 0.012 14.2 0.1 1.3 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EHU00994.1 - 0.0068 16.2 1.0 0.56 9.9 0.1 3.3 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA PF00004.29 EHU00994.1 - 0.011 16.2 1.5 0.4 11.1 1.5 2.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DLIC PF05783.11 EHU00994.1 - 0.048 12.5 0.0 0.084 11.7 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Dynamin_N PF00350.23 EHU00994.1 - 0.053 13.6 0.0 0.13 12.3 0.0 1.7 2 0 0 2 2 2 0 Dynamin family AAA_10 PF12846.7 EHU00994.1 - 0.063 12.2 0.1 0.19 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain ATPase_2 PF01637.18 EHU00994.1 - 0.26 11.2 0.7 41 4.0 0.0 3.0 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea DDE_Tnp_IS66 PF03050.14 EHU00995.1 - 1.3e-98 330.0 3.7 6.9e-98 327.6 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU00995.1 - 3.4e-16 59.2 0.1 1.3e-15 57.3 0.1 2.1 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU00995.1 - 1.4e-14 54.2 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU00995.1 - 8.7e-11 42.4 9.0 1.9e-10 41.4 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Phage_HK97_TLTM PF06120.11 EHU00995.1 - 0.029 13.6 0.7 0.056 12.6 0.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein UME PF08064.13 EHU00995.1 - 0.037 13.9 0.4 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain Exonuc_VII_L PF02601.15 EHU00995.1 - 0.05 13.2 3.1 0.044 13.4 0.9 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit FUSC PF04632.12 EHU00995.1 - 0.055 12.0 7.7 0.1 11.1 7.7 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Csm1_N PF18504.1 EHU00995.1 - 0.13 12.7 3.4 0.86 10.0 0.2 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Tho2 PF11262.8 EHU00995.1 - 0.17 11.1 0.3 0.28 10.4 0.3 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DHR10 PF18595.1 EHU00995.1 - 0.17 11.9 10.2 0.31 11.1 10.2 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain ERM PF00769.19 EHU00995.1 - 0.26 11.1 10.4 0.45 10.3 10.4 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family LXG PF04740.12 EHU00995.1 - 0.27 10.9 2.4 0.86 9.3 0.3 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily HHH_8 PF14716.6 EHU00995.1 - 0.34 11.3 4.0 0.56 10.6 1.9 2.4 2 1 0 2 2 2 0 Helix-hairpin-helix domain TSNAXIP1_N PF15739.5 EHU00995.1 - 0.45 10.9 3.2 0.99 9.8 3.2 1.5 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus Zn-ribbon_8 PF09723.10 EHU00995.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain FAM184 PF15665.5 EHU00995.1 - 0.49 10.2 7.3 0.78 9.5 7.3 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B TMPIT PF07851.13 EHU00995.1 - 0.75 9.0 2.7 1.2 8.4 2.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein CREPT PF16566.5 EHU00995.1 - 1.6 8.9 8.7 1.1 9.5 5.2 2.1 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour HAUS-augmin3 PF14932.6 EHU00995.1 - 2.4 7.7 7.4 5.8 6.4 7.4 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 SlyX PF04102.12 EHU00995.1 - 7.9 7.2 8.7 17 6.1 2.1 3.1 1 1 1 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHU00996.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHU00997.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU00997.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU00997.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU00997.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix BPD_transp_2 PF02653.16 EHU00998.1 - 7.5e-43 146.6 44.5 1.1e-42 146.1 44.5 1.2 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component adh_short_C2 PF13561.6 EHU00999.1 - 1.2e-61 208.2 2.5 1.1e-60 205.1 2.5 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EHU00999.1 - 4.3e-55 186.2 0.7 5.5e-55 185.8 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EHU00999.1 - 2.6e-12 47.0 0.8 3.6e-12 46.6 0.8 1.3 1 0 0 1 1 1 1 KR domain TLP1_add_C PF18313.1 EHU00999.1 - 0.083 12.8 0.4 7 6.7 0.0 2.9 3 1 0 3 3 3 0 Thiolase-like protein type 1 additional C-terminal domain Epimerase PF01370.21 EHU00999.1 - 0.11 12.0 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Bestrophin PF01062.21 EHU01000.1 - 9.9e-53 179.4 3.3 1.1e-52 179.3 3.3 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel BofA PF07441.11 EHU01000.1 - 1 9.6 6.3 1.7 8.9 2.7 2.4 2 0 0 2 2 2 0 SigmaK-factor processing regulatory protein BofA Porin_1 PF00267.21 EHU01001.1 - 1.4e-78 264.7 8.0 1.6e-78 264.5 8.0 1.0 1 0 0 1 1 1 1 Gram-negative porin Porin_4 PF13609.6 EHU01001.1 - 6e-13 49.2 16.8 7.7e-13 48.9 16.8 1.1 1 0 0 1 1 1 1 Gram-negative porin OMP_b-brl PF13505.6 EHU01001.1 - 0.075 13.1 16.0 0.21 11.7 16.0 2.0 1 1 0 1 1 1 0 Outer membrane protein beta-barrel domain Aminotran_3 PF00202.21 EHU01002.1 - 5.2e-122 407.4 0.2 6.5e-122 407.1 0.2 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_5 PF00266.19 EHU01002.1 - 0.00087 18.3 0.0 0.0015 17.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EHU01002.1 - 0.012 14.7 0.0 0.018 14.2 0.0 1.4 1 1 0 1 1 1 0 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EHU01002.1 - 0.091 12.0 0.1 0.23 10.7 0.1 1.6 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family AstA PF04958.12 EHU01003.1 - 4.8e-140 465.9 0.0 5.3e-140 465.7 0.0 1.0 1 0 0 1 1 1 1 Arginine N-succinyltransferase beta subunit Aldedh PF00171.22 EHU01004.1 - 4.4e-118 394.7 0.0 5.2e-118 394.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AstB PF04996.12 EHU01005.1 - 1.5e-212 706.1 0.2 1.7e-212 705.9 0.2 1.0 1 0 0 1 1 1 1 Succinylarginine dihydrolase AstE_AspA PF04952.14 EHU01006.1 - 1.2e-67 228.0 0.0 1.5e-67 227.7 0.0 1.0 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family LTXXQ PF07813.12 EHU01007.1 - 1.6e-21 76.9 6.2 2.7e-21 76.2 6.2 1.4 1 0 0 1 1 1 1 LTXXQ motif family protein Metal_resist PF13801.6 EHU01007.1 - 2.3e-10 40.8 6.7 5.1e-08 33.2 3.8 2.2 1 1 1 2 2 2 2 Heavy-metal resistance L1R_F9L PF02442.17 EHU01007.1 - 0.12 12.2 1.1 0.18 11.6 1.1 1.3 1 0 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses GIY-YIG PF01541.24 EHU01008.1 - 0.008 16.4 0.0 0.025 14.9 0.0 1.9 1 1 0 1 1 1 1 GIY-YIG catalytic domain RraB PF06877.11 EHU01008.1 - 0.065 14.0 0.0 0.17 12.6 0.0 1.6 1 0 0 1 1 1 0 Regulator of ribonuclease activity B NAD_synthase PF02540.17 EHU01009.1 - 5e-72 241.9 0.0 5.8e-72 241.7 0.0 1.0 1 0 0 1 1 1 1 NAD synthase MFS_1 PF07690.16 EHU01010.1 - 1e-38 133.2 43.9 1e-38 133.2 43.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Phage_tail_NK PF16532.5 EHU01010.1 - 0.046 13.3 0.2 0.12 12.0 0.2 1.7 1 0 0 1 1 1 0 Sf6-type phage tail needle knob or tip of some Caudovirales SmpA_OmlA PF04355.13 EHU01011.1 - 1e-12 47.6 0.4 1.3e-12 47.3 0.4 1.1 1 0 0 1 1 1 1 SmpA / OmlA family DUF4148 PF13663.6 EHU01011.1 - 0.012 15.8 0.1 0.018 15.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) LPAM_1 PF08139.12 EHU01011.1 - 0.45 11.1 3.2 0.67 10.6 3.2 1.3 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site SDF PF00375.18 EHU01013.1 - 2.7e-103 346.0 34.8 3.3e-103 345.7 34.8 1.1 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family YdjM PF04307.14 EHU01014.1 - 1.7e-32 112.1 6.7 2e-32 111.8 6.7 1.0 1 0 0 1 1 1 1 LexA-binding, inner membrane-associated putative hydrolase HupE_UreJ PF04955.12 EHU01014.1 - 0.026 14.0 0.5 0.041 13.4 0.5 1.3 1 0 0 1 1 1 0 HupE / UreJ protein DUF2227 PF09988.9 EHU01014.1 - 0.069 13.0 3.9 1.9 8.3 1.7 2.2 1 1 1 2 2 2 0 Uncharacterized metal-binding protein (DUF2227) HAD_2 PF13419.6 EHU01015.1 - 9e-25 87.8 0.0 1.1e-24 87.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EHU01015.1 - 4.3e-17 63.1 0.0 1.6e-15 57.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EHU01015.1 - 7.2e-08 33.0 0.0 1.8e-07 31.8 0.0 1.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EHU01015.1 - 0.00023 21.2 0.0 0.00039 20.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EHU01015.1 - 0.13 12.4 0.0 7 6.8 0.0 2.4 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase YniB PF14002.6 EHU01016.1 - 3.4e-77 257.9 1.5 3.8e-77 257.7 1.5 1.0 1 0 0 1 1 1 1 YniB-like protein OAD_gamma PF04277.13 EHU01016.1 - 0.025 15.2 0.3 0.025 15.2 0.3 1.8 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain RseC_MucC PF04246.12 EHU01016.1 - 0.052 13.5 0.4 0.052 13.5 0.4 2.0 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF2721 PF11026.8 EHU01016.1 - 0.13 12.1 3.4 2.6 7.9 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Fructosamin_kin PF03881.14 EHU01017.1 - 4.9e-110 367.3 0.0 5.5e-110 367.1 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 EHU01017.1 - 1.7e-18 67.5 1.7 2.1e-18 67.1 1.7 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family APH_6_hur PF04655.14 EHU01017.1 - 0.023 14.1 0.0 0.099 12.0 0.0 1.9 2 0 0 2 2 2 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase GhoS PF11080.8 EHU01018.1 - 3.8e-32 110.1 0.1 4.3e-32 110.0 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease GhoS DUF481 PF04338.12 EHU01019.1 - 1.3e-53 182.2 10.6 1.5e-53 182.0 10.6 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF481 OMP_b-brl PF13505.6 EHU01019.1 - 0.0052 16.9 16.4 0.01 16.0 16.4 1.6 1 1 0 1 1 1 1 Outer membrane protein beta-barrel domain HemolysinCabind PF00353.19 EHU01019.1 - 1.4 9.0 4.4 0.42 10.6 1.0 2.0 2 1 0 2 2 2 0 RTX calcium-binding nonapeptide repeat (4 copies) tRNA-synt_2b PF00587.25 EHU01020.1 - 3.5e-51 173.7 0.1 1.4e-50 171.8 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EHU01020.1 - 6.9e-22 77.4 0.9 2e-21 75.9 0.9 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 EHU01020.1 - 3.9e-14 52.5 0.0 7.4e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 EHU01020.1 - 1.9e-13 50.2 0.3 1.7e-12 47.2 0.1 2.3 2 0 0 2 2 2 1 TGS domain IF3_C PF00707.22 EHU01021.1 - 5.7e-36 122.4 0.3 1.1e-35 121.4 0.3 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 EHU01021.1 - 5.7e-32 109.8 0.0 1.2e-31 108.8 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain DUF3632 PF12311.8 EHU01021.1 - 0.2 12.1 0.0 0.27 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3632) Ribosomal_L35p PF01632.19 EHU01022.1 - 3.2e-24 85.2 8.1 3.3e-24 85.1 8.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L35 Ribosomal_L20 PF00453.18 EHU01023.1 - 2.4e-49 165.9 10.1 2.7e-49 165.7 10.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L20 SMC_ScpA PF02616.14 EHU01023.1 - 0.002 18.1 0.5 0.0028 17.6 0.5 1.2 1 0 0 1 1 1 1 Segregation and condensation protein ScpA DDE_Tnp_1 PF01609.21 EHU01024.1 - 5.5e-20 71.9 0.0 1e-19 71.0 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain tRNA-synt_2d PF01409.20 EHU01025.1 - 2.4e-107 358.0 0.1 2.9e-107 357.7 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) Phe_tRNA-synt_N PF02912.18 EHU01025.1 - 1.8e-26 91.8 1.7 2.7e-26 91.3 1.1 1.6 2 0 0 2 2 2 1 Aminoacyl tRNA synthetase class II, N-terminal domain tRNA_synthFbeta PF17759.1 EHU01025.1 - 0.0002 20.9 0.0 0.00064 19.2 0.0 1.8 2 0 0 2 2 2 1 Phenylalanyl tRNA synthetase beta chain CLM domain FAD-oxidase_C PF02913.19 EHU01025.1 - 0.082 12.5 0.3 0.42 10.2 0.1 1.8 1 1 1 2 2 2 0 FAD linked oxidases, C-terminal domain B3_4 PF03483.17 EHU01026.1 - 2.8e-69 232.2 0.0 4.2e-69 231.7 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain tRNA_synthFbeta PF17759.1 EHU01026.1 - 8.1e-55 185.6 0.0 1.6e-54 184.6 0.0 1.5 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain FDX-ACB PF03147.14 EHU01026.1 - 2e-28 98.7 0.0 4e-28 97.7 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA_bind PF01588.20 EHU01026.1 - 1e-27 96.0 0.2 5.2e-27 93.8 0.1 2.2 2 0 0 2 2 2 1 Putative tRNA binding domain B5 PF03484.15 EHU01026.1 - 1.3e-20 73.4 0.3 1.3e-19 70.2 0.1 2.6 2 0 0 2 2 2 1 tRNA synthetase B5 domain PhetRS_B1 PF18262.1 EHU01026.1 - 0.00046 20.4 0.0 0.36 11.1 0.0 3.3 4 0 0 4 4 4 2 Phe-tRNA synthetase beta subunit B1 domain Bac_DNA_binding PF00216.21 EHU01027.1 - 2.5e-30 104.5 0.1 2.8e-30 104.4 0.1 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 EHU01027.1 - 2e-07 31.1 0.0 2.5e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_bac_2 PF18175.1 EHU01027.1 - 2.4e-06 27.3 0.0 3.7e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 HU-CCDC81_euk_2 PF18289.1 EHU01027.1 - 0.026 14.7 0.0 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 HU-DNA_bdg PF14848.6 EHU01027.1 - 0.069 13.2 0.0 0.78 9.8 0.0 2.0 2 0 0 2 2 2 0 DNA-binding domain FecCD PF01032.18 EHU01028.1 - 4.1e-80 269.1 41.0 5.2e-80 268.8 41.0 1.0 1 0 0 1 1 1 1 FecCD transport family NUP PF06516.11 EHU01028.1 - 0.27 10.4 0.1 0.39 9.9 0.1 1.2 1 0 0 1 1 1 0 Purine nucleoside permease (NUP) ABC_tran PF00005.27 EHU01029.1 - 3.6e-22 79.3 0.0 5.5e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EHU01029.1 - 7.2e-09 35.9 0.1 9.6e-05 22.3 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EHU01029.1 - 2.7e-06 27.0 0.1 0.068 12.6 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EHU01029.1 - 0.00092 18.9 0.1 0.002 17.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EHU01029.1 - 0.0018 18.7 0.1 0.0039 17.6 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EHU01029.1 - 0.0022 18.3 0.1 0.022 15.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EHU01029.1 - 0.0025 17.4 1.7 0.0062 16.1 0.2 2.2 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 EHU01029.1 - 0.0026 18.3 0.1 0.004 17.7 0.1 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EHU01029.1 - 0.0046 16.9 0.1 0.011 15.6 0.1 1.6 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 EHU01029.1 - 0.0063 16.7 0.0 0.016 15.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EHU01029.1 - 0.013 15.3 0.0 0.098 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_27 PF13514.6 EHU01029.1 - 0.013 15.1 0.1 0.022 14.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EHU01029.1 - 0.022 14.8 0.0 0.047 13.8 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_30 PF13604.6 EHU01029.1 - 0.026 14.3 0.3 0.21 11.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EHU01029.1 - 0.033 14.1 0.5 0.85 9.5 0.1 2.2 2 0 0 2 2 2 0 NACHT domain SbcCD_C PF13558.6 EHU01029.1 - 0.034 14.4 0.0 0.055 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Mg_chelatase PF01078.21 EHU01029.1 - 0.053 12.9 0.5 0.1 11.9 0.5 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Ploopntkinase3 PF18751.1 EHU01029.1 - 0.054 13.4 0.0 0.092 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Dynamin_N PF00350.23 EHU01029.1 - 0.079 13.0 0.1 0.68 10.0 0.0 2.0 2 0 0 2 2 2 0 Dynamin family AAA_28 PF13521.6 EHU01029.1 - 0.085 13.1 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 EHU01029.1 - 0.13 11.8 0.2 0.9 9.1 0.1 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 EHU01029.1 - 0.2 11.4 0.8 3.3 7.4 0.3 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_13 PF13166.6 EHU01029.1 - 0.21 10.2 0.0 4.2 5.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 EHU01029.1 - 0.4 9.4 1.1 0.91 8.2 0.2 1.8 2 0 0 2 2 2 0 Predicted ATPase of the ABC class NLPC_P60 PF00877.19 EHU01030.1 - 8.6e-29 99.7 0.0 1e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 NlpC/P60 family DUF1175 PF06672.11 EHU01030.1 - 0.0059 16.3 0.0 0.081 12.6 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1175) CHAP PF05257.16 EHU01030.1 - 0.014 16.0 0.0 0.026 15.1 0.0 1.5 1 0 0 1 1 1 0 CHAP domain Peptidase_C92 PF05708.12 EHU01030.1 - 0.18 11.9 0.0 13 5.8 0.0 2.2 1 1 1 2 2 2 0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family EAL PF00563.20 EHU01031.1 - 2e-11 43.9 0.4 3.3e-11 43.2 0.4 1.3 1 1 0 1 1 1 1 EAL domain DAHP_synth_1 PF00793.20 EHU01032.1 - 2.7e-104 347.9 0.0 3.2e-104 347.7 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Kinase-PPPase PF03618.14 EHU01033.1 - 3.4e-72 243.3 0.0 3.8e-72 243.1 0.0 1.0 1 0 0 1 1 1 1 Kinase/pyrophosphorylase PPDK_N PF01326.19 EHU01034.1 - 2e-118 395.4 0.7 3e-118 394.9 0.7 1.2 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers_C PF02896.18 EHU01034.1 - 1.1e-59 202.0 0.0 2.1e-59 201.1 0.0 1.4 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.23 EHU01034.1 - 1e-27 95.6 0.6 2.5e-27 94.4 0.6 1.7 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain Polysacc_deac_2 PF04748.13 EHU01034.1 - 0.024 13.8 0.0 0.07 12.3 0.0 1.7 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase AI-2E_transport PF01594.16 EHU01035.1 - 6.7e-51 173.4 41.8 7.7e-51 173.2 41.8 1.0 1 0 0 1 1 1 1 AI-2E family transporter FAD-oxidase_C PF02913.19 EHU01036.1 - 1.8e-66 224.3 0.0 2.6e-66 223.8 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EHU01036.1 - 1.4e-35 122.0 0.1 2.5e-35 121.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Fer4_8 PF13183.6 EHU01036.1 - 8.6e-13 48.5 0.6 2.1e-12 47.3 0.6 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 EHU01036.1 - 0.00051 20.5 3.8 0.012 16.1 3.8 2.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain BBE PF08031.12 EHU01036.1 - 0.00094 19.2 0.0 0.0024 18.0 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Fer4_20 PF14691.6 EHU01036.1 - 0.0094 15.7 0.2 0.019 14.7 0.2 1.4 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_10 PF13237.6 EHU01036.1 - 0.014 15.5 1.4 0.037 14.1 1.4 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 EHU01036.1 - 0.03 14.5 0.2 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 4Fe-4S dicluster domain PrmC_N PF17827.1 EHU01036.1 - 0.039 14.5 0.0 0.18 12.4 0.0 2.2 1 0 0 1 1 1 0 PrmC N-terminal domain Fer4_7 PF12838.7 EHU01036.1 - 0.55 10.9 4.8 1.7 9.3 4.8 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain Tropomyosin PF00261.20 EHU01037.1 - 0.18 11.2 0.0 0.22 10.9 0.0 1.1 1 0 0 1 1 1 0 Tropomyosin Fe-S_biosyn PF01521.20 EHU01038.1 - 2.4e-18 66.4 0.0 2.7e-18 66.2 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis UPF0051 PF01458.17 EHU01039.1 - 3.2e-68 229.7 0.0 4.1e-68 229.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) ABC_tran PF00005.27 EHU01040.1 - 1.3e-21 77.6 0.0 1.6e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EHU01040.1 - 1.8e-08 34.1 1.3 5.1e-06 26.1 1.3 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EHU01040.1 - 4.1e-07 30.1 0.1 0.00084 19.2 0.1 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EHU01040.1 - 0.00029 20.5 0.0 0.00055 19.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EHU01040.1 - 0.0016 18.4 0.1 0.0025 17.7 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_13 PF13166.6 EHU01040.1 - 0.0025 16.6 0.0 0.0051 15.5 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EHU01040.1 - 0.0058 16.6 0.0 2.4 8.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 EHU01040.1 - 0.0069 16.9 0.1 0.029 14.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EHU01040.1 - 0.016 15.4 0.0 0.02 15.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 EHU01040.1 - 0.044 13.5 0.1 0.1 12.3 0.1 1.5 1 1 0 1 1 1 0 Cytidylate kinase AAA_27 PF13514.6 EHU01040.1 - 0.049 13.2 0.0 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EHU01040.1 - 0.05 13.2 0.1 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EHU01040.1 - 0.063 13.5 0.2 0.15 12.3 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EHU01040.1 - 0.075 13.6 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EHU01040.1 - 0.077 13.3 1.2 0.41 10.9 1.2 2.2 1 1 0 1 1 1 0 AAA domain Invasin_D3 PF09134.10 EHU01040.1 - 0.12 12.7 0.0 0.96 9.8 0.0 2.1 2 0 0 2 2 2 0 Invasin, domain 3 VirE PF05272.11 EHU01040.1 - 0.15 11.8 0.0 0.48 10.1 0.0 1.8 2 0 0 2 2 2 0 Virulence-associated protein E Ploopntkinase1 PF18748.1 EHU01040.1 - 0.18 11.3 0.0 0.8 9.2 0.0 1.8 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 UPF0051 PF01458.17 EHU01041.1 - 1.1e-71 241.0 5.7 1.5e-71 240.6 5.7 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) Aminotran_5 PF00266.19 EHU01042.1 - 1.3e-152 508.1 0.0 1.4e-152 507.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EHU01042.1 - 0.00013 21.4 0.1 0.00023 20.5 0.1 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EHU01042.1 - 0.0007 18.2 0.1 0.0028 16.3 0.1 1.8 1 1 1 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EHU01042.1 - 0.0014 18.0 1.3 0.0021 17.4 1.3 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SelA PF03841.13 EHU01042.1 - 0.047 12.7 0.1 0.1 11.5 0.0 1.6 2 0 0 2 2 2 0 L-seryl-tRNA selenium transferase SufE PF02657.15 EHU01043.1 - 6.3e-43 145.5 0.0 7.1e-43 145.3 0.0 1.0 1 0 0 1 1 1 1 Fe-S metabolism associated domain DUF943 PF06092.12 EHU01043.1 - 0.061 13.0 0.0 0.09 12.5 0.0 1.2 1 0 0 1 1 1 0 Enterobacterial putative membrane protein (DUF943) LPP PF04728.13 EHU01044.1 - 2.2e-25 88.8 10.2 2.6e-25 88.6 10.2 1.1 1 0 0 1 1 1 1 Lipoprotein leucine-zipper Alanine_zipper PF11839.8 EHU01044.1 - 0.00012 22.4 8.9 0.00015 22.0 7.4 1.7 1 1 1 2 2 2 1 Alanine-zipper, major outer membrane lipoprotein JIP_LZII PF16471.5 EHU01044.1 - 0.00066 19.8 0.2 0.0064 16.6 0.1 2.0 1 1 1 2 2 2 1 JNK-interacting protein leucine zipper II MctB PF11382.8 EHU01044.1 - 0.001 18.8 1.0 0.0011 18.7 1.0 1.0 1 0 0 1 1 1 1 Copper transport outer membrane protein, MctB ADIP PF11559.8 EHU01044.1 - 0.003 17.7 1.3 0.0035 17.5 1.3 1.0 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DivIC PF04977.15 EHU01044.1 - 0.0032 17.2 0.1 0.0041 16.9 0.1 1.3 1 0 0 1 1 1 1 Septum formation initiator EzrA PF06160.12 EHU01044.1 - 0.0046 15.2 0.3 0.005 15.1 0.3 1.0 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA NPV_P10 PF05531.12 EHU01044.1 - 0.0052 17.2 2.9 0.0075 16.7 2.9 1.3 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 EHU01044.1 - 0.0068 16.6 0.2 0.0075 16.5 0.2 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) TMF_DNA_bd PF12329.8 EHU01044.1 - 0.0087 16.0 0.2 0.011 15.7 0.2 1.1 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.12 EHU01044.1 - 0.01 15.9 1.9 0.011 15.8 1.9 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Rab5-bind PF09311.11 EHU01044.1 - 0.011 15.1 0.2 0.012 15.1 0.2 1.0 1 0 0 1 1 1 0 Rabaptin-like protein ZapB PF06005.12 EHU01044.1 - 0.014 15.8 0.4 0.019 15.4 0.4 1.1 1 0 0 1 1 1 0 Cell division protein ZapB Tropomyosin_1 PF12718.7 EHU01044.1 - 0.016 15.3 1.1 0.018 15.2 1.1 1.1 1 0 0 1 1 1 0 Tropomyosin like DUF1664 PF07889.12 EHU01044.1 - 0.018 15.1 0.2 0.024 14.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) YscO PF07321.12 EHU01044.1 - 0.018 15.0 1.7 0.021 14.8 1.7 1.0 1 0 0 1 1 1 0 Type III secretion protein YscO Cluap1 PF10234.9 EHU01044.1 - 0.023 14.1 1.1 0.029 13.8 1.1 1.0 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF16 PF01519.16 EHU01044.1 - 0.026 15.0 0.1 0.032 14.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF3138 PF11336.8 EHU01044.1 - 0.036 12.7 0.7 0.037 12.6 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) AKNA PF12443.8 EHU01044.1 - 0.045 14.4 0.1 0.053 14.2 0.1 1.2 1 0 0 1 1 1 0 AT-hook-containing transcription factor Atg14 PF10186.9 EHU01044.1 - 0.045 12.8 0.3 0.046 12.8 0.3 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 EHU01044.1 - 0.049 12.5 0.4 0.054 12.4 0.4 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein COG2 PF06148.11 EHU01044.1 - 0.051 13.7 0.2 0.056 13.5 0.2 1.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 MbeD_MobD PF04899.12 EHU01044.1 - 0.067 13.3 0.6 0.1 12.7 0.1 1.5 2 0 0 2 2 2 0 MbeD/MobD like FlaC_arch PF05377.11 EHU01044.1 - 0.08 13.3 0.2 0.11 12.9 0.2 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) XhlA PF10779.9 EHU01044.1 - 1.4 9.2 6.0 0.27 11.5 1.3 2.1 2 1 1 3 3 2 0 Haemolysin XhlA DUF4407 PF14362.6 EHU01044.1 - 3.4 6.9 7.9 0.89 8.8 4.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) PK PF00224.21 EHU01045.1 - 6.1e-153 508.8 8.5 8e-153 508.4 8.5 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EHU01045.1 - 4e-27 94.8 0.8 4e-27 94.8 0.8 1.8 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EHU01045.1 - 0.00011 21.4 0.2 0.00035 19.8 0.2 1.8 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DUF2187 PF09953.9 EHU01045.1 - 0.08 12.9 0.3 0.32 11.0 0.3 2.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2187) MatE PF01554.18 EHU01046.1 - 6.8e-73 243.6 25.3 1.9e-38 131.7 4.9 2.9 4 0 0 4 4 4 2 MatE Polysacc_synt_C PF14667.6 EHU01046.1 - 5.7e-09 36.2 17.8 4.4e-08 33.3 6.5 4.9 2 2 2 5 5 5 2 Polysaccharide biosynthesis C-terminal domain DUF1673 PF07895.11 EHU01046.1 - 2.7 7.7 5.2 3.4 7.3 0.4 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1673) Lum_binding PF00677.17 EHU01047.1 - 4e-45 151.7 1.9 1.9e-21 75.8 0.0 2.4 3 0 0 3 3 3 2 Lumazine binding domain ILVD_EDD PF00920.21 EHU01047.1 - 0.079 11.6 0.5 0.15 10.7 0.1 1.5 2 0 0 2 2 2 0 Dehydratase family MFS_1 PF07690.16 EHU01048.1 - 3.9e-38 131.3 47.6 3.9e-38 131.3 47.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EHU01048.1 - 1.1e-07 31.1 11.9 1.1e-07 31.1 11.9 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter DUF2474 PF10617.9 EHU01048.1 - 0.39 10.6 8.1 0.089 12.7 3.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2474) LysR_substrate PF03466.20 EHU01049.1 - 1.5e-29 102.9 1.4 2.1e-29 102.4 1.4 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EHU01049.1 - 1.5e-17 63.2 0.1 3e-17 62.3 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_28 PF13518.6 EHU01049.1 - 0.032 14.4 0.3 0.66 10.1 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Peripla_BP_3 PF13377.6 EHU01050.1 - 1.1e-41 143.0 0.1 2.7e-41 141.7 0.0 1.6 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 EHU01050.1 - 1.6e-36 126.2 0.0 1.9e-36 125.9 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 EHU01050.1 - 6e-23 81.7 0.0 8.2e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain LacI PF00356.21 EHU01050.1 - 1.4e-18 66.4 0.1 2.4e-18 65.6 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family HTH_38 PF13936.6 EHU01050.1 - 0.0076 16.0 0.3 0.53 10.1 0.1 2.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 EHU01050.1 - 0.011 15.2 0.3 0.029 13.8 0.3 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 PucR PF07905.11 EHU01050.1 - 0.011 16.0 0.0 0.024 14.9 0.0 1.6 1 1 0 1 1 1 0 Purine catabolism regulatory protein-like family HTH_3 PF01381.22 EHU01050.1 - 0.011 15.7 0.0 0.038 14.0 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix MarR_2 PF12802.7 EHU01050.1 - 0.023 14.6 0.2 10 6.1 0.1 2.6 2 0 0 2 2 2 0 MarR family HTH_23 PF13384.6 EHU01050.1 - 0.034 14.0 0.2 0.41 10.5 0.1 2.3 1 1 1 2 2 2 0 Homeodomain-like domain HTH_24 PF13412.6 EHU01050.1 - 0.044 13.4 1.7 0.67 9.6 0.0 3.0 4 0 0 4 4 4 0 Winged helix-turn-helix DNA-binding HTH_10 PF04967.12 EHU01050.1 - 0.07 12.9 0.2 0.32 10.8 0.0 2.1 2 0 0 2 2 2 0 HTH DNA binding domain MerR PF00376.23 EHU01050.1 - 0.1 12.4 0.2 0.27 11.0 0.2 1.8 1 0 0 1 1 1 0 MerR family regulatory protein TetR_N PF00440.23 EHU01050.1 - 0.12 12.2 0.1 0.31 10.9 0.1 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family HTH_31 PF13560.6 EHU01050.1 - 0.12 12.7 0.0 0.39 11.1 0.0 1.9 1 1 0 1 1 1 0 Helix-turn-helix domain NLPC_P60 PF00877.19 EHU01051.1 - 4.7e-31 106.9 0.1 1.2e-30 105.6 0.1 1.7 1 0 0 1 1 1 1 NlpC/P60 family Peptidase_C92 PF05708.12 EHU01051.1 - 0.0016 18.6 3.3 0.014 15.5 1.9 2.4 2 2 0 2 2 2 1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family DUF1175 PF06672.11 EHU01051.1 - 0.0067 16.1 0.2 0.53 9.9 0.0 2.7 1 1 2 3 3 3 1 Protein of unknown function (DUF1175) Presenilin PF01080.17 EHU01051.1 - 0.015 14.1 1.6 0.017 13.9 1.6 1.1 1 0 0 1 1 1 0 Presenilin Amidase_6 PF12671.7 EHU01051.1 - 0.019 15.0 2.4 0.025 14.7 0.0 2.0 1 1 1 2 2 2 0 Putative amidase domain CHAP PF05257.16 EHU01051.1 - 0.034 14.7 0.5 0.16 12.6 0.0 2.2 1 1 0 2 2 2 0 CHAP domain Atg14 PF10186.9 EHU01051.1 - 0.35 9.9 11.3 0.48 9.4 11.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 XRN_M PF17846.1 EHU01051.1 - 3.2 6.6 10.8 4.2 6.2 10.8 1.1 1 0 0 1 1 1 0 Xrn1 helical domain MMM1 PF10296.9 EHU01051.1 - 3.4 6.6 7.4 1.4 7.9 5.2 1.4 1 1 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 LRAT PF04970.13 EHU01051.1 - 4.8 7.5 6.2 2.9 8.2 0.0 2.4 2 1 0 2 2 2 0 Lecithin retinol acyltransferase GREB1 PF15782.5 EHU01051.1 - 4.9 4.1 8.4 6 3.9 8.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hid1 PF12722.7 EHU01051.1 - 7.3 4.6 8.7 8.9 4.3 8.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Glutaredoxin PF00462.24 EHU01052.1 - 7.5e-19 67.7 0.0 1e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin RNase_T PF00929.24 EHU01053.1 - 2.6e-39 135.4 0.1 3e-39 135.2 0.1 1.0 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 EHU01053.1 - 1.9e-06 27.9 0.1 2.7e-05 24.2 0.1 2.0 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like Glyoxalase PF00903.25 EHU01054.1 - 9.5e-25 87.3 0.0 1.1e-24 87.0 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EHU01054.1 - 1.3e-07 31.8 0.0 7.2e-07 29.4 0.0 1.9 1 1 1 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EHU01054.1 - 1.7e-06 28.7 0.0 2.7e-06 28.1 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase-like domain CppA_N PF14506.6 EHU01054.1 - 0.054 13.6 0.0 0.084 12.9 0.0 1.4 1 0 0 1 1 1 0 CppA N-terminal Oxidored_FMN PF00724.20 EHU01055.1 - 4e-87 292.7 0.0 4.6e-87 292.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family TetR_C_13 PF16925.5 EHU01056.1 - 2.5e-13 49.9 0.0 3.6e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 EHU01056.1 - 3.7e-09 36.2 0.0 1e-08 34.8 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family DUF1289 PF06945.13 EHU01057.1 - 3.5e-18 65.1 6.7 4.5e-18 64.8 6.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1289) Aldo_ket_red PF00248.21 EHU01058.1 - 1.2e-35 123.2 0.0 1.4e-35 122.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DDE_Tnp_1_5 PF13737.6 EHU01059.1 - 5.9e-45 152.2 0.0 1.6e-44 150.8 0.0 1.7 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 EHU01059.1 - 1.9e-24 86.5 1.0 2.3e-24 86.2 1.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain Aldo_ket_red PF00248.21 EHU01060.1 - 9.4e-07 28.3 0.0 9.9e-07 28.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Sod_Cu PF00080.20 EHU01061.1 - 1.2e-31 109.8 0.6 1.6e-31 109.4 0.6 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) SEF14_adhesin PF06443.11 EHU01061.1 - 0.32 10.9 4.7 2.8 7.8 3.6 2.2 2 1 0 2 2 2 0 SEF14-like adhesin Tektin PF03148.14 EHU01062.1 - 0.0054 15.5 0.2 0.0068 15.2 0.2 1.0 1 0 0 1 1 1 1 Tektin family CobD_Cbib PF03186.13 EHU01062.1 - 0.04 13.1 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 CobD/Cbib protein HTH_Tnp_1 PF01527.20 EHU01063.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU01063.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU01063.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU01063.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHU01064.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHU01065.1 - 1.1e-97 326.9 4.0 3.8e-97 325.1 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU01065.1 - 3.2e-16 59.2 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU01065.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU01065.1 - 1.2e-11 45.2 9.0 2.6e-11 44.1 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHU01065.1 - 0.017 14.9 6.4 0.027 14.3 6.4 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Phage_HK97_TLTM PF06120.11 EHU01065.1 - 0.022 14.0 1.7 0.042 13.0 1.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHU01065.1 - 0.022 15.1 4.3 0.091 13.1 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain FUSC PF04632.12 EHU01065.1 - 0.038 12.6 6.8 0.06 11.9 6.8 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 EHU01065.1 - 0.04 13.5 2.2 0.047 13.2 0.8 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Tho2 PF11262.8 EHU01065.1 - 0.057 12.6 0.5 0.094 11.9 0.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Troponin PF00992.20 EHU01065.1 - 0.062 13.6 3.0 0.11 12.8 3.0 1.3 1 0 0 1 1 1 0 Troponin LXG PF04740.12 EHU01065.1 - 0.11 12.3 2.5 0.32 10.7 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily UME PF08064.13 EHU01065.1 - 0.15 12.0 0.5 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain ERM PF00769.19 EHU01065.1 - 0.16 11.8 10.8 0.26 11.1 10.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HalX PF08663.10 EHU01065.1 - 0.23 11.8 3.1 0.59 10.5 3.1 1.7 1 0 0 1 1 1 0 HalX domain DHR10 PF18595.1 EHU01065.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Zn-ribbon_8 PF09723.10 EHU01065.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF1192 PF06698.11 EHU01065.1 - 0.53 10.4 5.3 3.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHU01065.1 - 1.1 8.4 3.1 1.7 7.8 3.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHU01065.1 - 2.8 7.4 7.9 6.1 6.3 7.9 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHU01065.1 - 3.3 8.1 7.9 6.7 7.0 7.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 EHU01065.1 - 7.2 7.3 8.7 7.7 7.2 1.0 3.0 1 1 1 2 2 2 0 SlyX DUF1656 PF07869.12 EHU01066.1 - 1.1e-14 54.2 8.1 1.5e-14 53.7 8.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1656) MarR PF01047.22 EHU01067.1 - 3.1e-18 65.4 0.8 7.7e-18 64.2 0.2 1.9 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.7 EHU01067.1 - 2.9e-12 46.3 0.1 6.7e-12 45.1 0.1 1.6 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 EHU01067.1 - 6.1e-11 42.6 0.2 1e-10 41.9 0.2 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_Crp_2 PF13545.6 EHU01067.1 - 3.8e-05 23.6 1.9 0.00018 21.4 0.9 2.5 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain HTH_24 PF13412.6 EHU01067.1 - 0.0015 18.1 0.1 0.0051 16.3 0.1 2.0 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding B-block_TFIIIC PF04182.12 EHU01067.1 - 0.0028 17.8 0.0 0.004 17.3 0.0 1.4 1 1 0 1 1 1 1 B-block binding subunit of TFIIIC HxlR PF01638.17 EHU01067.1 - 0.004 17.0 0.8 0.017 15.0 0.2 2.0 1 1 1 2 2 2 1 HxlR-like helix-turn-helix DUF1845 PF08900.11 EHU01067.1 - 0.005 16.6 0.2 0.0056 16.5 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1845) GntR PF00392.21 EHU01067.1 - 0.0059 16.2 0.2 0.036 13.7 0.0 2.2 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family TrmB PF01978.19 EHU01067.1 - 0.0084 16.0 0.0 0.03 14.2 0.0 1.8 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_36 PF13730.6 EHU01067.1 - 0.013 15.4 0.0 0.062 13.3 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_20 PF12840.7 EHU01067.1 - 0.013 15.5 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4423 PF14394.6 EHU01067.1 - 0.014 15.2 1.2 0.17 11.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) HTH_5 PF01022.20 EHU01067.1 - 0.027 14.3 0.0 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family LexA_DNA_bind PF01726.16 EHU01067.1 - 0.031 14.1 0.0 0.098 12.4 0.0 1.8 1 0 0 1 1 1 0 LexA DNA binding domain Replic_Relax PF13814.6 EHU01067.1 - 0.038 14.0 0.1 0.049 13.7 0.1 1.2 1 0 0 1 1 1 0 Replication-relaxation GlnD_UR_UTase PF08335.11 EHU01067.1 - 0.04 14.0 0.5 0.16 12.1 0.3 2.2 1 1 1 2 2 2 0 GlnD PII-uridylyltransferase RsbU_N PF08673.10 EHU01067.1 - 0.089 12.9 0.1 0.24 11.5 0.0 1.7 2 0 0 2 2 2 0 Phosphoserine phosphatase RsbU, N-terminal domain Fe_dep_repress PF01325.19 EHU01067.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Rick_17kDa_Anti PF05433.15 EHU01068.1 - 1.4e-06 28.0 27.1 1.4e-06 28.0 27.1 1.7 2 0 0 2 2 2 1 Glycine zipper 2TM domain DUF3221 PF11518.8 EHU01068.1 - 0.019 15.3 0.1 0.085 13.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3221) DUF533 PF04391.12 EHU01068.1 - 0.26 10.8 3.4 0.39 10.3 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Bacteriocin_IIc PF10439.9 EHU01068.1 - 0.33 11.1 21.1 0.045 13.9 16.8 1.8 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_Omp PF13488.6 EHU01068.1 - 0.81 9.7 29.7 0.43 10.6 26.1 2.3 2 1 0 2 2 2 0 Glycine zipper AnmK PF03702.14 EHU01069.1 - 2.6e-169 563.1 0.8 3e-169 562.9 0.8 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase FGGY_C PF02782.16 EHU01069.1 - 0.0076 16.0 0.2 0.022 14.5 0.1 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DUF4060 PF13269.6 EHU01070.1 - 8.6e-40 134.7 1.2 9.5e-40 134.5 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4060) RecO_N PF11967.8 EHU01070.1 - 0.041 13.8 0.2 0.078 13.0 0.2 1.4 1 0 0 1 1 1 0 Recombination protein O N terminal DUF2575 PF10837.8 EHU01070.1 - 0.056 13.8 0.0 0.057 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2575) EAL PF00563.20 EHU01071.1 - 3.9e-48 164.0 0.1 5.6e-48 163.5 0.1 1.2 1 0 0 1 1 1 1 EAL domain BLUF PF04940.12 EHU01071.1 - 6.1e-24 84.0 0.0 1.2e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 Sensors of blue-light using FAD DDE_3 PF13358.6 EHU01072.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHU01072.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHU01072.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHU01072.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHU01072.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHU01072.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHU01072.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHU01072.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 DDE_Tnp_IS66 PF03050.14 EHU01073.1 - 2.8e-99 332.1 3.5 1.6e-98 329.7 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU01073.1 - 3.1e-16 59.3 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU01073.1 - 8e-15 55.0 1.3 1.9e-14 53.8 1.3 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU01073.1 - 1.7e-11 44.7 9.6 3.5e-11 43.7 9.6 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHU01073.1 - 0.017 14.9 6.4 0.027 14.3 6.4 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Phage_HK97_TLTM PF06120.11 EHU01073.1 - 0.021 14.0 1.7 0.042 13.0 1.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHU01073.1 - 0.022 15.1 4.3 0.091 13.1 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Exonuc_VII_L PF02601.15 EHU01073.1 - 0.028 14.0 1.8 0.039 13.5 0.6 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit FUSC PF04632.12 EHU01073.1 - 0.03 12.9 6.9 0.056 12.0 6.9 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tho2 PF11262.8 EHU01073.1 - 0.057 12.6 0.5 0.094 11.9 0.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Troponin PF00992.20 EHU01073.1 - 0.062 13.6 3.0 0.11 12.8 3.0 1.3 1 0 0 1 1 1 0 Troponin LXG PF04740.12 EHU01073.1 - 0.11 12.2 2.6 0.33 10.6 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHU01073.1 - 0.16 11.8 10.8 0.26 11.1 10.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family UME PF08064.13 EHU01073.1 - 0.16 11.9 0.5 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain HalX PF08663.10 EHU01073.1 - 0.23 11.8 3.1 0.59 10.5 3.1 1.7 1 0 0 1 1 1 0 HalX domain DHR10 PF18595.1 EHU01073.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF1192 PF06698.11 EHU01073.1 - 0.47 10.5 5.3 3.4 7.8 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHU01073.1 - 1.1 8.4 3.1 1.7 7.8 3.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHU01073.1 - 2.8 7.4 7.9 6.1 6.3 7.9 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHU01073.1 - 3.2 8.1 7.9 6.7 7.0 7.9 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 EHU01073.1 - 7.1 7.3 8.7 7.7 7.2 1.0 3.1 1 1 1 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHU01074.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHU01075.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU01075.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU01075.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU01075.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix YrhK PF14145.6 EHU01077.1 - 2e-18 66.0 2.7 2.4e-18 65.7 2.7 1.1 1 0 0 1 1 1 1 YrhK-like protein DUF1129 PF06570.11 EHU01079.1 - 0.0028 17.2 0.3 0.0032 17.0 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1129) KdpC PF02669.15 EHU01079.1 - 0.34 10.7 1.1 2.4 8.0 0.2 1.9 1 1 1 2 2 2 0 K+-transporting ATPase, c chain Sulfate_transp PF00916.20 EHU01080.1 - 3.7e-38 131.3 37.3 6.9e-23 81.0 8.5 2.5 1 1 1 2 2 2 2 Sulfate permease family MFS_MOT1 PF16983.5 EHU01080.1 - 5e-07 30.1 44.3 0.00019 21.8 4.7 4.2 3 1 1 4 4 4 3 Molybdate transporter of MFS superfamily STAS PF01740.21 EHU01080.1 - 1.8e-05 24.3 0.0 3.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 STAS domain QCR10 PF09796.9 EHU01080.1 - 0.0079 16.2 0.6 0.0079 16.2 0.6 3.1 3 0 0 3 3 3 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DUF543 PF04418.12 EHU01080.1 - 0.099 12.6 0.5 0.56 10.2 0.5 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF543) HCO3_cotransp PF00955.21 EHU01080.1 - 0.32 9.8 11.1 0.12 11.2 0.8 2.4 2 0 0 2 2 2 0 HCO3- transporter family YmgB PF10798.8 EHU01081.1 - 1.2e-27 95.5 0.6 1.6e-27 95.1 0.6 1.2 1 0 0 1 1 1 1 Biofilm development protein YmgB/AriR AraC_binding PF02311.19 EHU01082.1 - 4e-23 81.8 5.4 8.4e-23 80.8 5.4 1.6 1 1 0 1 1 1 1 AraC-like ligand binding domain HTH_18 PF12833.7 EHU01082.1 - 1.2e-19 70.3 2.2 4.6e-19 68.5 0.4 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_AraC PF00165.23 EHU01082.1 - 2.7e-11 43.2 0.1 0.00044 20.3 0.0 3.3 3 0 0 3 3 3 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_31 PF13560.6 EHU01082.1 - 0.0062 16.9 3.0 3.8 7.9 0.0 2.9 3 0 0 3 3 3 2 Helix-turn-helix domain Peptidase_M24 PF00557.24 EHU01082.1 - 0.15 11.7 0.1 0.23 11.1 0.1 1.3 1 0 0 1 1 1 0 Metallopeptidase family M24 MarR PF01047.22 EHU01083.1 - 1.1e-09 38.1 0.2 4.1e-09 36.2 0.1 1.9 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.7 EHU01083.1 - 1.5e-09 37.6 0.2 3e-09 36.6 0.2 1.5 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 EHU01083.1 - 2.8e-09 37.3 0.1 5.4e-09 36.4 0.1 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 EHU01083.1 - 0.0037 17.0 0.2 0.0037 17.0 0.2 1.9 2 0 0 2 2 2 1 IclR helix-turn-helix domain PadR PF03551.14 EHU01083.1 - 0.018 15.0 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family HTH_34 PF13601.6 EHU01083.1 - 0.079 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain MFS_1 PF07690.16 EHU01084.1 - 4.9e-14 52.0 40.8 4.9e-14 52.0 40.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Phage_T4_Ndd PF06591.11 EHU01084.1 - 0.035 13.9 0.0 3.4 7.4 0.0 2.4 2 0 0 2 2 2 0 T4-like phage nuclear disruption protein (Ndd) Pico_P2B PF01552.17 EHU01084.1 - 0.14 12.3 1.0 0.45 10.7 0.0 2.3 2 1 0 2 2 2 0 Picornavirus 2B protein DUF4148 PF13663.6 EHU01084.1 - 0.19 12.0 2.5 1.3 9.3 0.6 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) DUF872 PF05915.12 EHU01084.1 - 1 9.5 3.5 1.9 8.7 0.4 2.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF4381 PF14316.6 EHU01084.1 - 3.3 7.9 12.7 4.4 7.5 3.6 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4381) HlyD_D23 PF16576.5 EHU01085.1 - 4.8e-16 58.6 13.0 1.2e-14 54.1 10.8 2.6 2 1 0 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 EHU01085.1 - 4.4e-13 48.8 1.0 4.4e-13 48.8 1.0 4.5 5 1 0 5 5 5 2 Biotin-lipoyl like HlyD_3 PF13437.6 EHU01085.1 - 2e-11 44.5 13.0 3e-09 37.5 0.3 3.9 2 2 2 4 4 4 2 HlyD family secretion protein HlyD PF00529.20 EHU01085.1 - 1.6e-10 40.7 1.4 2.2e-10 40.3 1.4 1.3 1 0 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl PF00364.22 EHU01085.1 - 0.0017 18.2 0.1 0.83 9.5 0.0 2.5 2 0 0 2 2 2 2 Biotin-requiring enzyme XRN_M PF17846.1 EHU01085.1 - 0.07 12.1 2.2 0.1 11.6 2.2 1.3 1 0 0 1 1 1 0 Xrn1 helical domain ToxN_toxin PF13958.6 EHU01085.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Toxin ToxN, type III toxin-antitoxin system Attacin_C PF03769.15 EHU01085.1 - 3.2 8.0 6.1 5.8 7.2 6.1 1.4 1 0 0 1 1 1 0 Attacin, C-terminal region OEP PF02321.18 EHU01086.1 - 4.6e-46 157.0 40.3 6.3e-28 97.9 15.5 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein YkyA PF10368.9 EHU01086.1 - 0.00066 19.4 2.7 0.0016 18.2 2.7 1.6 1 0 0 1 1 1 1 Putative cell-wall binding lipoprotein CsoSCA PF08936.10 EHU01086.1 - 0.013 14.2 0.6 0.02 13.5 0.6 1.2 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase PLDc_2 PF13091.6 EHU01089.1 - 8.4e-41 139.0 0.0 9.5e-23 80.5 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EHU01089.1 - 0.0011 19.0 0.0 0.0079 16.3 0.0 2.2 2 0 0 2 2 2 1 Phospholipase D Active site motif Acyl_transf_3 PF01757.22 EHU01090.1 - 7.2e-29 100.9 42.0 8.5e-29 100.7 42.0 1.1 1 0 0 1 1 1 1 Acyltransferase family PGG PF13962.6 EHU01090.1 - 8.6 6.2 10.0 1.4 8.8 1.0 2.8 3 0 0 3 3 3 0 Domain of unknown function MdoG PF04349.12 EHU01091.1 - 1.6e-198 660.5 0.1 1.8e-198 660.3 0.1 1.0 1 0 0 1 1 1 1 Periplasmic glucan biosynthesis protein, MdoG Glycos_transf_2 PF00535.26 EHU01092.1 - 4.5e-21 75.4 0.0 6.7e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 EHU01092.1 - 1.1e-11 45.0 6.8 1.1e-11 45.0 6.8 2.8 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 EHU01092.1 - 9.8e-08 31.7 0.0 2.7e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 21 Arv1 PF04161.13 EHU01092.1 - 0.6 10.2 4.8 3.2 7.8 0.1 2.3 2 0 0 2 2 2 0 Arv1-like family DUF1375 PF07119.12 EHU01093.1 - 4.6e-06 26.9 4.5 4.6e-06 26.9 4.5 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1375) XPB_DRD PF18458.1 EHU01093.1 - 0.15 12.0 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Xeroderma pigmentosum group B helicase damage recognition domain DUF3568 PF12092.8 EHU01093.1 - 0.16 12.0 0.1 0.2 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) LPAM_2 PF13627.6 EHU01093.1 - 1.2 9.1 4.2 2.6 8.0 4.2 1.7 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site MsyB PF13984.6 EHU01094.1 - 1.2e-64 216.1 10.2 1.4e-64 215.9 10.2 1.0 1 0 0 1 1 1 1 MsyB protein PhoLip_ATPase_C PF16212.5 EHU01095.1 - 0.49 10.1 9.5 0.61 9.8 9.5 1.1 1 0 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal DUF2070 PF09843.9 EHU01095.1 - 5.1 5.3 7.2 6.2 5.0 7.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Lip_A_acyltrans PF03279.13 EHU01096.1 - 5e-103 344.3 0.0 5.6e-103 344.2 0.0 1.0 1 0 0 1 1 1 1 Bacterial lipid A biosynthesis acyltransferase UPF0176_N PF17773.1 EHU01097.1 - 2.9e-20 72.4 0.0 5e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 EHU01097.1 - 1.6e-19 70.0 14.2 3e-19 69.2 14.2 1.4 1 0 0 1 1 1 1 Rhodanase C-terminal Rhodanese PF00581.20 EHU01097.1 - 2.3e-12 47.3 0.1 4e-12 46.6 0.1 1.4 1 0 0 1 1 1 1 Rhodanese-like domain TERT_thumb PF17984.1 EHU01097.1 - 0.033 14.1 0.2 0.17 11.7 0.0 2.1 1 1 1 2 2 2 0 Telomerase reverse transcriptase thumb DNA binding domain YceI PF04264.13 EHU01098.1 - 1.1e-41 142.8 0.4 1.3e-41 142.6 0.4 1.1 1 0 0 1 1 1 1 YceI-like domain Ni_hydr_CYTB PF01292.20 EHU01099.1 - 7.1e-29 100.7 16.4 8.3e-29 100.5 16.4 1.0 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 DUF4405 PF14358.6 EHU01099.1 - 0.0033 17.9 6.5 0.0033 17.9 6.5 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4405) Cytochrom_B561 PF03188.16 EHU01099.1 - 0.065 13.4 7.9 0.026 14.7 3.8 2.1 2 1 0 2 2 2 0 Eukaryotic cytochrome b561 DUF2427 PF10348.9 EHU01099.1 - 0.075 12.8 8.9 1.8 8.4 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) DUF1145 PF06611.12 EHU01099.1 - 5.7 7.0 14.1 1.5 8.8 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1145) DAO PF01266.24 EHU01100.1 - 2.4e-48 165.5 0.1 2.7e-48 165.4 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EHU01100.1 - 3e-05 23.4 0.0 0.029 13.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EHU01100.1 - 0.00058 19.2 0.0 0.0082 15.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EHU01100.1 - 0.00066 18.5 0.1 0.66 8.6 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 EHU01100.1 - 0.0042 17.3 0.1 0.0091 16.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EHU01100.1 - 0.0058 16.0 1.0 0.011 15.1 0.8 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EHU01100.1 - 0.0098 15.0 0.2 0.014 14.5 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EHU01100.1 - 0.026 13.7 0.1 0.039 13.2 0.1 1.2 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 EHU01100.1 - 0.028 13.5 0.3 0.056 12.5 0.2 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 EHU01100.1 - 0.14 12.1 0.1 0.2 11.5 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 EHU01100.1 - 0.2 10.9 0.1 0.36 10.0 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain BssS PF13991.6 EHU01101.1 - 4.6e-37 125.9 0.1 5.2e-37 125.8 0.1 1.0 1 0 0 1 1 1 1 BssS protein family DinI PF06183.13 EHU01103.1 - 2.7e-29 101.3 0.3 3.2e-29 101.0 0.3 1.1 1 0 0 1 1 1 1 DinI-like family DUF2868 PF11067.8 EHU01103.1 - 0.042 13.4 0.1 0.049 13.1 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) YtxH PF12732.7 EHU01103.1 - 0.14 12.7 0.0 0.71 10.4 0.0 1.9 1 1 0 1 1 1 0 YtxH-like protein Amidohydro_1 PF01979.20 EHU01104.1 - 3.1e-17 62.9 0.0 4.2e-17 62.5 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family DUF1439 PF07273.12 EHU01105.1 - 4.6e-55 185.6 1.1 5.3e-55 185.4 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1439) APG5 PF04106.12 EHU01105.1 - 0.067 12.8 0.1 0.081 12.5 0.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg5 LPAM_1 PF08139.12 EHU01105.1 - 0.072 13.6 0.5 0.15 12.6 0.5 1.6 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Acetyltransf_3 PF13302.7 EHU01106.1 - 6.3e-16 59.3 0.1 7.8e-16 59.0 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EHU01106.1 - 2.9e-08 34.0 0.0 3.7e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EHU01106.1 - 2.4e-05 24.6 0.0 3.1e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 EHU01106.1 - 0.0025 17.5 0.0 0.0037 16.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF480 PF04337.12 EHU01107.1 - 1.7e-62 210.0 0.2 1.7e-62 210.0 0.2 1.8 2 1 0 2 2 2 1 Protein of unknown function, DUF480 ABC_tran_CTD PF16326.5 EHU01107.1 - 0.0037 17.5 2.1 0.021 15.1 1.2 2.4 2 0 0 2 2 2 1 ABC transporter C-terminal domain MbeD_MobD PF04899.12 EHU01107.1 - 0.015 15.4 0.3 0.077 13.1 0.1 2.2 2 0 0 2 2 2 0 MbeD/MobD like CLZ PF16526.5 EHU01107.1 - 0.14 12.6 3.1 0.4 11.1 1.3 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4140 PF13600.6 EHU01107.1 - 0.47 10.9 3.3 0.79 10.2 3.3 1.6 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Csm1_N PF18504.1 EHU01107.1 - 0.79 10.1 5.7 0.98 9.8 1.0 2.7 3 0 0 3 3 3 0 Csm1 N-terminal domain TSC22 PF01166.18 EHU01107.1 - 2.1 8.8 5.2 1.7 9.1 1.3 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family Osmo_CC PF08946.10 EHU01107.1 - 3.8 7.8 6.1 0.74 10.1 1.8 2.1 3 0 0 3 3 3 0 Osmosensory transporter coiled coil GFO_IDH_MocA PF01408.22 EHU01108.1 - 3.3e-29 102.1 0.1 9.9e-29 100.6 0.1 1.8 3 0 0 3 3 3 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 EHU01108.1 - 0.0096 16.5 0.0 0.039 14.5 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Ketoacyl-synt_2 PF13723.6 EHU01108.1 - 0.042 13.5 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain DUF1611_N PF17396.2 EHU01108.1 - 0.17 12.2 1.1 29 5.0 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1611_N) Rossmann-like domain MurJ PF03023.14 EHU01109.1 - 8e-152 506.0 28.0 9.4e-152 505.7 28.0 1.0 1 0 0 1 1 1 1 Lipid II flippase MurJ Polysacc_synt_C PF14667.6 EHU01109.1 - 4.6e-10 39.7 14.0 4.6e-10 39.7 14.0 4.0 4 1 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain MCPsignal PF00015.21 EHU01110.1 - 8.9e-52 175.4 17.9 8.9e-52 175.4 17.9 3.3 4 0 0 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain T7SS_ESX_EspC PF10824.8 EHU01110.1 - 0.0029 18.0 1.1 0.0029 18.0 1.1 4.4 1 1 2 4 4 4 1 Excreted virulence factor EspC, type VII ESX diderm HAMP PF00672.25 EHU01110.1 - 0.023 15.1 0.7 0.58 10.6 0.0 3.4 3 1 0 3 3 3 0 HAMP domain PhoU_div PF01865.16 EHU01110.1 - 0.1 11.9 0.1 0.1 11.9 0.1 3.8 3 2 2 5 5 5 0 Protein of unknown function DUF47 Nup54 PF13874.6 EHU01110.1 - 0.48 10.5 9.5 0.98 9.5 3.4 2.8 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 DUF4570 PF15134.6 EHU01110.1 - 0.77 9.8 3.6 1.1 9.4 0.1 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4570) DUF948 PF06103.11 EHU01110.1 - 1.6 9.0 26.4 2 8.7 0.7 5.4 2 1 3 5 5 5 0 Bacterial protein of unknown function (DUF948) Synaptobrevin PF00957.21 EHU01110.1 - 2.9 7.8 11.3 1.4 8.8 0.3 3.6 3 0 0 3 3 3 0 Synaptobrevin PhoU PF01895.19 EHU01110.1 - 3 8.4 7.6 16 6.1 0.3 3.8 2 1 0 4 4 4 0 PhoU domain FlgN PF05130.12 EHU01111.1 - 8.8e-23 81.4 0.9 1e-22 81.2 0.9 1.0 1 0 0 1 1 1 1 FlgN protein FlgM PF04316.13 EHU01112.1 - 1.8e-09 37.8 0.9 2.7e-09 37.2 0.9 1.5 1 1 0 1 1 1 1 Anti-sigma-28 factor, FlgM Flg_bb_rod PF00460.20 EHU01113.1 - 4.6e-12 45.6 0.1 1.2e-11 44.3 0.0 1.8 2 0 0 2 2 2 1 Flagella basal body rod protein Flg_bbr_C PF06429.13 EHU01114.1 - 6.1e-11 42.3 4.1 6.1e-11 42.3 4.1 1.9 1 1 0 1 1 1 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 EHU01114.1 - 2.6e-10 40.0 1.2 7.6e-10 38.5 1.2 1.8 1 0 0 1 1 1 1 Flagella basal body rod protein Caveolin PF01146.17 EHU01114.1 - 0.05 13.6 0.0 0.072 13.1 0.0 1.2 1 0 0 1 1 1 0 Caveolin FlgD_ig PF13860.6 EHU01115.1 - 3.1e-23 81.4 2.4 6.4e-23 80.4 2.4 1.5 1 0 0 1 1 1 1 FlgD Ig-like domain FlgD PF03963.14 EHU01115.1 - 9.6e-22 77.1 10.2 9.6e-22 77.1 10.2 1.9 2 0 0 2 2 2 1 Flagellar hook capping protein - N-terminal region FLgD_tudor PF13861.6 EHU01115.1 - 3.4e-16 59.2 0.0 1.3e-15 57.4 0.0 2.0 1 1 0 1 1 1 1 FlgD Tudor-like domain MG2 PF01835.19 EHU01115.1 - 0.03 14.8 0.1 0.066 13.7 0.1 1.5 1 0 0 1 1 1 0 MG2 domain DUF2271 PF10029.9 EHU01115.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2271) Chlorovi_GP_rpt PF06598.11 EHU01115.1 - 0.23 11.5 4.1 0.42 10.7 2.4 2.4 2 0 0 2 2 2 0 Chlorovirus glycoprotein repeat He_PIG PF05345.12 EHU01115.1 - 0.46 10.7 8.2 5.3 7.3 0.1 3.0 2 1 0 2 2 2 0 Putative Ig domain Flg_bbr_C PF06429.13 EHU01116.1 - 2.8e-22 78.6 2.0 2.8e-22 78.6 2.0 2.8 3 0 0 3 3 3 1 Flagellar basal body rod FlgEFG protein C-terminal FlaE PF07559.14 EHU01116.1 - 5.2e-16 59.3 10.7 5.2e-16 59.3 10.7 2.7 3 0 0 3 3 3 1 Flagellar basal body protein FlaE Flg_bb_rod PF00460.20 EHU01116.1 - 5.9e-10 38.9 2.3 5.9e-10 38.9 2.3 3.2 2 0 0 2 2 2 1 Flagella basal body rod protein Flg_bbr_C PF06429.13 EHU01117.1 - 1.6e-22 79.4 4.1 1.8e-22 79.3 1.4 2.3 2 0 0 2 2 2 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 EHU01117.1 - 3.3e-10 39.7 1.5 3.3e-10 39.7 1.5 2.7 3 0 0 3 3 3 1 Flagella basal body rod protein IglC PF11550.8 EHU01117.1 - 0.058 12.8 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Intracellular growth locus C protein Flg_bbr_C PF06429.13 EHU01118.1 - 2.8e-25 88.3 3.3 4.3e-25 87.6 1.5 2.3 2 0 0 2 2 2 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 EHU01118.1 - 2.3e-13 49.7 0.9 7.3e-13 48.1 0.9 2.0 1 0 0 1 1 1 1 Flagella basal body rod protein BclA_C PF18573.1 EHU01118.1 - 0.1 12.5 4.6 1.3 8.9 4.5 2.3 1 1 1 2 2 2 0 BclA C-terminal domain DDE_3 PF13358.6 EHU01119.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHU01119.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHU01119.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHU01119.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHU01119.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHU01119.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHU01119.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHU01119.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 FlgH PF02107.16 EHU01120.1 - 2.4e-59 199.7 0.3 2.8e-59 199.5 0.3 1.0 1 0 0 1 1 1 1 Flagellar L-ring protein FlgI PF02119.16 EHU01121.1 - 6.2e-134 446.3 19.1 7.1e-134 446.1 19.1 1.0 1 0 0 1 1 1 1 Flagellar P-ring protein Propep_M14 PF02244.16 EHU01121.1 - 0.015 15.7 0.0 0.063 13.7 0.0 2.1 1 0 0 1 1 1 0 Carboxypeptidase activation peptide Glucosaminidase PF01832.20 EHU01122.1 - 3.3e-21 75.6 0.7 5.5e-21 74.9 0.7 1.4 1 0 0 1 1 1 1 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Rod-binding PF10135.9 EHU01122.1 - 2.2e-15 56.9 0.4 2.2e-15 56.9 0.4 2.4 3 0 0 3 3 3 1 Rod binding protein Flg_bbr_C PF06429.13 EHU01123.1 - 6.4e-08 32.6 4.7 6.4e-08 32.6 4.7 3.6 2 1 1 3 3 3 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 EHU01123.1 - 1.3e-06 28.2 6.1 1.3e-06 28.2 6.1 4.2 5 0 0 5 5 5 1 Flagella basal body rod protein DUF1664 PF07889.12 EHU01123.1 - 0.32 11.0 6.1 0.4 10.7 1.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CooC_C PF15976.5 EHU01123.1 - 0.72 9.9 3.9 0.79 9.8 0.2 2.9 2 1 0 2 2 2 0 CS1-pili formation C-terminal Flagellin_N PF00669.20 EHU01124.1 - 1.7e-22 80.0 7.4 1.7e-22 80.0 7.4 2.9 2 1 1 3 3 3 2 Bacterial flagellin N-terminal helical region Flagellin_C PF00700.21 EHU01124.1 - 5.4e-06 26.7 15.4 8.5e-05 22.8 4.3 3.5 3 0 0 3 3 3 2 Bacterial flagellin C-terminal helical region DUF2802 PF10975.8 EHU01124.1 - 0.4 10.9 2.4 2.2 8.5 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2802) DDE_Tnp_IS66 PF03050.14 EHU01125.1 - 1.1e-97 326.9 4.5 3.8e-97 325.1 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU01125.1 - 3.2e-16 59.3 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU01125.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU01125.1 - 8.7e-11 42.4 9.0 1.9e-10 41.4 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Phage_HK97_TLTM PF06120.11 EHU01125.1 - 0.011 15.0 0.8 0.021 14.0 0.8 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHU01125.1 - 0.02 15.2 4.2 0.084 13.2 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain UME PF08064.13 EHU01125.1 - 0.033 14.1 0.3 20 5.1 0.0 3.1 2 1 1 3 3 3 0 UME (NUC010) domain Exonuc_VII_L PF02601.15 EHU01125.1 - 0.039 13.5 2.7 0.04 13.5 1.0 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Troponin PF00992.20 EHU01125.1 - 0.044 14.1 2.8 0.078 13.3 2.8 1.3 1 0 0 1 1 1 0 Troponin FUSC PF04632.12 EHU01125.1 - 0.048 12.2 7.4 0.077 11.5 7.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tho2 PF11262.8 EHU01125.1 - 0.049 12.8 0.6 0.081 12.1 0.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FAM184 PF15665.5 EHU01125.1 - 0.052 13.3 8.0 0.082 12.7 8.0 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B HalX PF08663.10 EHU01125.1 - 0.13 12.6 2.4 0.34 11.3 2.4 1.7 1 0 0 1 1 1 0 HalX domain LXG PF04740.12 EHU01125.1 - 0.14 11.8 2.8 0.35 10.5 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHU01125.1 - 0.19 11.5 11.1 0.31 10.8 11.1 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DHR10 PF18595.1 EHU01125.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Zn-ribbon_8 PF09723.10 EHU01125.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF1192 PF06698.11 EHU01125.1 - 0.54 10.4 5.3 3.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHU01125.1 - 0.82 8.9 3.0 1.2 8.3 3.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHU01125.1 - 2 8.0 8.1 4.3 6.8 8.1 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHU01125.1 - 4.2 7.7 8.6 8.7 6.7 8.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CREPT PF16566.5 EHU01125.1 - 5.9 7.1 8.7 2.7 8.1 5.6 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour SlyX PF04102.12 EHU01125.1 - 9.3 7.0 9.0 18 6.1 2.3 3.0 1 1 1 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHU01126.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHU01127.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU01127.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU01127.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU01127.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix RNase_E_G PF10150.9 EHU01128.1 - 7.6e-93 310.8 1.1 8.4e-93 310.7 0.0 1.7 2 0 0 2 2 2 1 Ribonuclease E/G family PNPase_C PF12111.8 EHU01128.1 - 9.7e-19 66.5 6.2 9.7e-19 66.5 6.2 2.7 2 0 0 2 2 2 1 Polyribonucleotide phosphorylase C terminal S1 PF00575.23 EHU01128.1 - 6.8e-17 61.6 0.0 1.7e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 S1 RNA binding domain PseudoU_synth_2 PF00849.22 EHU01129.1 - 7.1e-31 107.5 0.0 1.2e-30 106.7 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 EHU01129.1 - 1.1e-11 44.2 0.4 1.9e-11 43.5 0.4 1.4 1 0 0 1 1 1 1 S4 domain PAD PF03068.15 EHU01129.1 - 0.1 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) Maf PF02545.14 EHU01130.1 - 2e-45 154.6 0.0 2.2e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein YceD PF02620.17 EHU01131.1 - 1.1e-17 64.3 0.7 1.6e-17 63.7 0.7 1.3 1 0 0 1 1 1 1 Large ribosomal RNA subunit accumulation protein YceD zinc_ribbon_4 PF13717.6 EHU01131.1 - 0.048 13.6 0.7 0.34 10.9 0.7 2.1 1 1 0 1 1 1 0 zinc-ribbon domain Trm112p PF03966.16 EHU01131.1 - 0.051 14.2 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 Trm112p-like protein Ribosomal_L32p PF01783.23 EHU01132.1 - 1e-19 70.5 0.6 1.1e-19 70.5 0.6 1.0 1 0 0 1 1 1 1 Ribosomal L32p protein family FA_synthesis PF02504.15 EHU01133.1 - 6.6e-116 386.9 0.0 7.5e-116 386.7 0.0 1.0 1 0 0 1 1 1 1 Fatty acid synthesis protein ACP_syn_III_C PF08541.10 EHU01134.1 - 1.3e-37 127.9 2.7 1.7e-37 127.5 0.0 2.5 3 1 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 EHU01134.1 - 4.4e-31 106.6 0.5 8.9e-31 105.6 0.5 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Chal_sti_synt_N PF00195.19 EHU01134.1 - 4e-05 23.1 0.4 6.5e-05 22.5 0.4 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain HMG_CoA_synt_N PF01154.17 EHU01134.1 - 4.7e-05 23.3 0.1 7.4e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Thiolase_N PF00108.23 EHU01134.1 - 0.00026 20.4 0.9 0.00026 20.4 0.9 2.0 2 2 0 2 2 2 1 Thiolase, N-terminal domain FAE1_CUT1_RppA PF08392.12 EHU01134.1 - 0.001 18.4 0.1 0.0029 17.0 0.0 1.7 2 0 0 2 2 2 1 FAE1/Type III polyketide synthase-like protein Ketoacyl-synt_C PF02801.22 EHU01134.1 - 0.066 13.2 0.1 0.3 11.1 0.0 2.1 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 EHU01135.1 - 1.2e-41 143.2 2.5 1.5e-41 143.0 2.5 1.0 1 0 0 1 1 1 1 Acyl transferase domain adh_short_C2 PF13561.6 EHU01136.1 - 3.9e-68 229.5 7.7 4.5e-68 229.3 7.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EHU01136.1 - 8.6e-62 208.1 3.7 1e-61 207.8 3.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EHU01136.1 - 6.1e-19 68.6 3.8 8.7e-19 68.1 3.4 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EHU01136.1 - 4.7e-06 26.6 2.3 5.9e-06 26.3 2.3 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EHU01136.1 - 0.00064 19.3 0.4 0.001 18.6 0.4 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 EHU01136.1 - 0.039 13.8 2.6 0.24 11.2 0.7 2.3 1 1 1 2 2 2 0 DNA / pantothenate metabolism flavoprotein Sacchrp_dh_NADP PF03435.18 EHU01136.1 - 0.069 13.4 0.1 0.13 12.5 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 EHU01136.1 - 0.083 12.0 0.3 0.21 10.6 0.1 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain PP-binding PF00550.25 EHU01137.1 - 5.1e-17 62.0 0.4 5.7e-17 61.8 0.4 1.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 EHU01137.1 - 1.1e-06 28.8 1.2 1.3e-06 28.5 1.2 1.3 1 1 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.12 EHU01137.1 - 0.0048 17.3 0.7 0.0053 17.2 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) TerB PF05099.13 EHU01137.1 - 0.013 15.5 0.2 0.015 15.3 0.2 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TerB Ribosomal_L50 PF10501.9 EHU01137.1 - 0.015 15.4 0.1 0.025 14.7 0.1 1.5 1 1 0 1 1 1 0 Ribosomal subunit 39S DUF1896 PF08989.10 EHU01137.1 - 0.038 14.1 0.1 0.041 14.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1896) HLH PF00010.26 EHU01137.1 - 0.06 13.3 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain ketoacyl-synt PF00109.26 EHU01138.1 - 3.3e-61 207.0 0.5 3.3e-61 207.0 0.5 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EHU01138.1 - 1.9e-40 137.5 0.9 3.9e-40 136.6 0.9 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EHU01138.1 - 3e-05 23.5 0.6 6.2e-05 22.5 0.6 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 EHU01138.1 - 0.012 15.4 6.3 0.81 9.6 0.0 3.7 4 0 0 4 4 4 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III KAsynt_C_assoc PF16197.5 EHU01138.1 - 0.18 12.3 0.1 0.67 10.4 0.1 2.0 2 0 0 2 2 2 0 Ketoacyl-synthetase C-terminal extension Aminotran_4 PF01063.19 EHU01139.1 - 1.3e-46 159.2 0.0 1.6e-46 159.0 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV YceG PF02618.16 EHU01140.1 - 3.6e-82 276.0 0.1 4.2e-82 275.8 0.1 1.0 1 0 0 1 1 1 1 YceG-like family DUF3979 PF13141.6 EHU01140.1 - 0.16 12.2 0.1 1.5 9.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3979) Thymidylate_kin PF02223.17 EHU01141.1 - 7e-58 195.3 0.0 8e-58 195.2 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase dNK PF01712.19 EHU01141.1 - 5.5e-06 26.4 0.0 0.0049 16.8 0.0 2.1 2 0 0 2 2 2 2 Deoxynucleoside kinase AAA_28 PF13521.6 EHU01141.1 - 2e-05 24.9 0.3 2.7e-05 24.5 0.3 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EHU01141.1 - 0.0015 18.8 0.0 0.003 17.9 0.0 1.6 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 EHU01141.1 - 0.0091 16.6 0.0 0.069 13.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EHU01141.1 - 0.014 15.8 0.1 6.2 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EHU01141.1 - 0.018 14.8 0.4 0.033 13.9 0.3 1.6 1 1 0 1 1 1 0 AAA domain LpxK PF02606.14 EHU01141.1 - 0.018 14.2 0.1 0.026 13.6 0.1 1.2 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase AAA_33 PF13671.6 EHU01141.1 - 0.019 15.1 0.5 0.1 12.8 0.5 2.2 1 1 0 1 1 1 0 AAA domain Sin_N PF04801.13 EHU01141.1 - 0.16 11.2 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region DNA_pol3_delta2 PF13177.6 EHU01142.1 - 1e-39 135.9 0.0 1.7e-39 135.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DNApol3-delta_C PF09115.10 EHU01142.1 - 4.2e-35 120.8 7.9 9.1e-35 119.7 7.9 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit, C terminal TatD_DNase PF01026.21 EHU01143.1 - 4.2e-75 252.4 0.0 4.8e-75 252.2 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase PTS_EIIC PF02378.18 EHU01144.1 - 4.5e-83 279.0 31.3 4.5e-83 279.0 31.3 1.6 2 0 0 2 2 2 1 Phosphotransferase system, EIIC PTS_EIIB PF00367.20 EHU01144.1 - 4.4e-14 51.7 0.4 7.4e-14 51.0 0.4 1.4 1 0 0 1 1 1 1 phosphotransferase system, EIIB MCPsignal PF00015.21 EHU01145.1 - 1.7e-49 167.9 37.6 2e-49 167.7 18.1 3.5 2 2 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.7 EHU01145.1 - 4.2e-11 42.7 2.4 2.1e-10 40.4 0.0 3.1 2 1 0 2 2 2 1 Four helix bundle sensory module for signal transduction Snf7 PF03357.21 EHU01145.1 - 0.0014 18.3 2.2 0.0014 18.3 2.2 2.5 3 1 0 3 3 3 1 Snf7 TarH PF02203.15 EHU01145.1 - 0.0014 18.6 1.4 0.0014 18.6 1.4 5.1 6 1 0 6 6 5 1 Tar ligand binding domain homologue IFT57 PF10498.9 EHU01145.1 - 0.0049 15.9 0.7 0.0049 15.9 0.7 2.0 2 0 0 2 2 2 1 Intra-flagellar transport protein 57 DUF4795 PF16043.5 EHU01145.1 - 0.037 13.6 0.4 0.037 13.6 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Lebercilin PF15619.6 EHU01145.1 - 0.046 13.4 0.3 0.046 13.4 0.3 2.2 3 0 0 3 3 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF1664 PF07889.12 EHU01145.1 - 0.094 12.8 11.5 0.18 11.9 2.6 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) LapA_dom PF06305.11 EHU01145.1 - 0.19 11.6 6.0 0.12 12.2 1.6 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain TMPIT PF07851.13 EHU01145.1 - 0.19 10.9 4.4 0.68 9.1 0.4 2.4 2 0 0 2 2 2 0 TMPIT-like protein Acetyltransf_11 PF13720.6 EHU01145.1 - 0.23 12.0 2.1 55 4.3 0.0 3.8 3 2 1 4 4 4 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Atg14 PF10186.9 EHU01145.1 - 0.57 9.2 4.5 0.74 8.8 0.8 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Folliculin PF11704.8 EHU01145.1 - 0.9 9.4 6.9 0.6 10.0 1.1 2.6 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Syntaxin-6_N PF09177.11 EHU01145.1 - 1.3 9.6 6.9 0.9 10.1 1.8 2.9 3 1 0 3 3 3 0 Syntaxin 6, N-terminal Laminin_II PF06009.12 EHU01145.1 - 3.3 7.7 16.6 4.1 7.4 6.5 3.7 2 1 0 2 2 2 0 Laminin Domain II T3SS_needle_F PF09392.10 EHU01145.1 - 6.2 7.1 8.3 1.9 8.7 0.7 3.4 2 1 0 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF HIT PF01230.23 EHU01146.1 - 1.5e-28 99.4 0.0 1.7e-28 99.2 0.0 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EHU01146.1 - 6e-22 78.3 0.0 6.3e-22 78.2 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF1425 PF07233.12 EHU01147.1 - 3.2e-24 84.7 0.0 3.8e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1425) LpoB PF13036.6 EHU01148.1 - 2.1e-34 118.6 0.2 3e-34 118.1 0.2 1.2 1 0 0 1 1 1 1 Peptidoglycan-synthase activator LpoB FlgT_M PF16539.5 EHU01148.1 - 0.022 14.9 0.3 0.033 14.3 0.3 1.3 1 0 0 1 1 1 0 Flagellar assembly protein T, middle domain APH PF01636.23 EHU01149.1 - 4.6e-18 66.0 7.6 4.6e-18 66.0 7.6 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EHU01149.1 - 3e-06 27.0 0.0 0.00028 20.5 0.0 2.2 1 1 1 2 2 2 2 Choline/ethanolamine kinase Glyco_hydro_3 PF00933.21 EHU01150.1 - 4.8e-98 328.5 0.2 5.9e-98 328.2 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain UPF0227 PF05728.12 EHU01151.1 - 2.5e-62 210.2 0.0 2.8e-62 210.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Pyr_redox_2 PF07992.14 EHU01152.1 - 6.4e-67 225.8 0.2 7.5e-67 225.6 0.2 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EHU01152.1 - 1.2e-16 61.1 2.4 7.3e-11 42.5 0.3 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EHU01152.1 - 4.5e-09 36.4 2.3 0.035 13.7 0.0 4.1 4 0 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EHU01152.1 - 0.00014 21.9 4.3 0.041 13.9 0.1 3.6 3 1 1 4 4 4 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EHU01152.1 - 0.00016 20.9 0.5 0.25 10.4 0.0 3.2 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EHU01152.1 - 0.00019 20.8 0.7 0.16 11.2 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EHU01152.1 - 0.00086 18.1 2.3 0.48 9.1 0.1 3.6 5 0 0 5 5 5 2 HI0933-like protein K_oxygenase PF13434.6 EHU01152.1 - 0.0036 16.5 0.1 1.2 8.2 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) ApbA PF02558.16 EHU01152.1 - 0.016 14.9 0.8 2.8 7.6 0.1 2.4 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 EHU01152.1 - 0.027 14.7 4.2 0.86 9.9 0.1 3.1 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 EHU01152.1 - 0.053 12.4 3.3 0.81 8.5 0.1 2.9 2 1 0 3 3 3 0 Tryptophan halogenase FAD_binding_3 PF01494.19 EHU01152.1 - 0.06 12.6 0.5 4.3 6.5 0.1 2.4 2 0 0 2 2 2 0 FAD binding domain ThiF PF00899.21 EHU01152.1 - 0.099 12.0 1.0 6.3 6.1 0.0 2.3 2 0 0 2 2 2 0 ThiF family TrkA_N PF02254.18 EHU01152.1 - 0.12 12.6 0.1 9.7 6.5 0.0 2.6 2 0 0 2 2 2 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.23 EHU01152.1 - 0.14 12.2 0.4 0.93 9.5 0.1 2.1 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Rick_17kDa_Anti PF05433.15 EHU01153.1 - 3e-11 43.0 17.1 3e-11 43.0 17.1 2.1 2 0 0 2 2 2 1 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.6 EHU01153.1 - 5.1e-05 22.9 14.9 5.1e-05 22.9 14.9 2.2 2 0 0 2 2 2 1 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 EHU01153.1 - 0.0036 17.3 15.5 0.0036 17.3 15.5 2.3 2 0 0 2 2 2 1 Glycine zipper TraT PF05818.12 EHU01153.1 - 0.02 14.6 0.6 0.02 14.6 0.6 1.5 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein DUF533 PF04391.12 EHU01153.1 - 2.5 7.6 5.5 5.9 6.4 2.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF533) Fusion_gly PF00523.18 EHU01153.1 - 3.9 5.6 4.8 1.8 6.7 0.0 2.0 2 0 0 2 2 2 0 Fusion glycoprotein F0 MFS_1 PF07690.16 EHU01154.1 - 8e-42 143.4 45.0 8e-42 143.4 45.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EHU01154.1 - 0.09 12.0 30.3 0.42 9.9 8.4 2.6 1 1 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB FliC_SP PF12613.8 EHU01154.1 - 1 9.9 3.9 1.1 9.8 0.6 2.7 2 0 0 2 2 2 0 Flagellin structural protein TRCF PF03461.15 EHU01155.1 - 2.8e-28 98.1 0.0 1.8e-27 95.6 0.0 2.4 3 0 0 3 3 3 1 TRCF domain CarD_CdnL_TRCF PF02559.16 EHU01155.1 - 6.5e-25 87.7 0.0 2.6e-24 85.8 0.0 2.1 1 0 0 1 1 1 1 CarD-like/TRCF domain UvrB_inter PF17757.1 EHU01155.1 - 1.6e-21 76.2 0.0 3.7e-21 75.1 0.0 1.7 1 0 0 1 1 1 1 UvrB interaction domain Helicase_C PF00271.31 EHU01155.1 - 6e-21 74.9 1.5 1.8e-17 63.6 0.4 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 EHU01155.1 - 2.9e-19 69.5 0.0 6.7e-19 68.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EHU01155.1 - 9.8e-12 45.2 0.0 2.4e-11 43.9 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UB2H PF14814.6 EHU01155.1 - 5e-07 29.7 0.3 1.5e-05 24.9 0.0 2.7 2 0 0 2 2 2 1 Bifunctional transglycosylase second domain SNF2_N PF00176.23 EHU01155.1 - 0.00055 18.8 0.0 0.00079 18.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ERCC3_RAD25_C PF16203.5 EHU01155.1 - 0.0015 17.8 0.0 0.0029 16.8 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase MacB_PCD PF12704.7 EHU01157.1 - 8.7e-13 49.1 0.8 8.7e-13 49.1 0.8 2.0 2 0 0 2 2 2 1 MacB-like periplasmic core domain FtsX PF02687.21 EHU01157.1 - 4.2e-11 43.2 4.9 4.2e-11 43.2 4.9 2.9 3 0 0 3 3 3 1 FtsX-like permease family Sigma_reg_N PF13800.6 EHU01157.1 - 0.1 12.9 1.4 0.58 10.5 0.1 2.4 2 0 0 2 2 2 0 Sigma factor regulator N-terminal HPS6 PF15702.5 EHU01157.1 - 0.12 10.3 0.1 0.16 9.9 0.1 1.1 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 6 protein ABC_tran PF00005.27 EHU01158.1 - 5.2e-36 124.2 0.0 7.7e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EHU01158.1 - 4.5e-07 30.0 0.0 0.028 14.2 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EHU01158.1 - 3.9e-06 26.5 0.2 0.0038 16.7 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EHU01158.1 - 0.00017 21.2 0.1 0.00039 20.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EHU01158.1 - 0.0013 19.2 2.0 0.0047 17.3 2.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EHU01158.1 - 0.0025 18.1 0.9 0.06 13.6 0.9 2.2 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 EHU01158.1 - 0.0028 17.8 0.1 0.06 13.6 0.1 2.4 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 EHU01158.1 - 0.0033 17.3 0.0 0.0058 16.6 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_33 PF13671.6 EHU01158.1 - 0.0069 16.5 1.6 0.054 13.7 1.6 2.1 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 EHU01158.1 - 0.02 14.6 0.1 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_23 PF13476.6 EHU01158.1 - 0.024 15.1 0.0 0.038 14.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EHU01158.1 - 0.044 13.1 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_30 PF13604.6 EHU01158.1 - 0.047 13.4 0.3 0.57 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EHU01158.1 - 0.056 13.5 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 EHU01158.1 - 0.13 12.4 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.12 EHU01158.1 - 0.14 12.1 0.2 0.29 11.0 0.2 1.5 1 0 0 1 1 1 0 NACHT domain AAA_15 PF13175.6 EHU01158.1 - 0.18 11.5 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain MacB_PCD PF12704.7 EHU01159.1 - 1.5e-14 54.8 0.4 1.5e-14 54.8 0.4 2.5 3 0 0 3 3 3 1 MacB-like periplasmic core domain FtsX PF02687.21 EHU01159.1 - 1.3e-13 51.2 12.8 2.8e-13 50.1 2.1 3.4 3 0 0 3 3 3 2 FtsX-like permease family Arteri_GP4 PF02497.15 EHU01159.1 - 0.16 12.1 0.6 0.38 10.9 0.2 1.7 1 1 0 1 1 1 0 Arterivirus glycoprotein SIR2 PF02146.17 EHU01160.1 - 3.1e-53 180.3 0.0 5.1e-53 179.6 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 EHU01160.1 - 0.00027 20.7 0.0 0.00059 19.6 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain M20_dimer PF07687.14 EHU01161.1 - 1e-10 41.5 0.0 1.7e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 EHU01161.1 - 1.3e-05 25.0 0.4 3.3e-05 23.7 0.1 1.8 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 EHU01161.1 - 0.0003 19.9 0.1 0.00047 19.3 0.1 1.2 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.17 EHU01161.1 - 0.071 12.8 0.4 0.11 12.1 0.1 1.5 2 0 0 2 2 2 0 Peptidase family M28 Peptidase_M20 PF01546.28 EHU01162.1 - 1.5e-05 24.8 0.0 1.6e-05 24.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Cupin_4 PF08007.12 EHU01163.1 - 2.1e-102 342.9 0.0 2.5e-102 342.6 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.11 EHU01163.1 - 0.0036 17.0 0.3 0.23 11.2 0.0 2.8 3 0 0 3 3 3 1 Cupin domain Cupin_1 PF00190.22 EHU01163.1 - 0.01 15.5 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 0 Cupin Cupin_8 PF13621.6 EHU01163.1 - 0.032 13.9 0.0 0.15 11.7 0.0 2.0 1 1 0 2 2 2 0 Cupin-like domain AraC_binding PF02311.19 EHU01163.1 - 0.089 12.7 0.3 0.27 11.1 0.3 1.9 1 1 0 1 1 1 0 AraC-like ligand binding domain JmjC PF02373.22 EHU01163.1 - 0.15 12.5 0.0 0.93 9.9 0.0 2.1 2 0 0 2 2 2 0 JmjC domain, hydroxylase PhoQ_Sensor PF08918.10 EHU01164.1 - 3.7e-85 284.3 0.3 5.6e-85 283.7 0.3 1.3 1 0 0 1 1 1 1 PhoQ Sensor HATPase_c PF02518.26 EHU01164.1 - 9.4e-14 51.9 0.0 1.6e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 EHU01164.1 - 6.8e-07 29.1 0.0 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 GHKL domain HAMP PF00672.25 EHU01164.1 - 5.7e-06 26.6 1.3 4e-05 23.9 0.2 2.3 2 0 0 2 2 2 1 HAMP domain HisKA PF00512.25 EHU01164.1 - 0.00078 19.4 1.2 0.0013 18.7 0.1 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 EHU01164.1 - 0.054 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 EHU01164.1 - 0.085 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EHU01165.1 - 6.3e-24 84.3 0.0 9.9e-24 83.7 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 EHU01165.1 - 8.1e-20 70.7 0.1 1.7e-19 69.6 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal FleQ PF06490.11 EHU01165.1 - 0.0052 17.1 0.0 0.0088 16.4 0.0 1.4 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ Lyase_1 PF00206.20 EHU01166.1 - 1.1e-77 261.5 0.0 1.4e-77 261.2 0.0 1.1 1 0 0 1 1 1 1 Lyase ASL_C PF08328.11 EHU01166.1 - 3.2e-52 175.5 0.0 1e-51 173.9 0.0 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal DUF489 PF04356.12 EHU01167.1 - 2.2e-72 243.1 3.5 2.6e-72 242.9 3.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF489) TolA_bind_tri PF16331.5 EHU01167.1 - 0.088 12.9 2.5 0.29 11.2 2.5 1.8 1 0 0 1 1 1 0 TolA binding protein trimerisation Pox_A_type_inc PF04508.12 EHU01167.1 - 0.13 12.1 0.1 1.9 8.5 0.0 2.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat tRNA_Me_trans PF03054.16 EHU01168.1 - 2e-142 474.2 0.0 2.3e-142 474.0 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 EHU01168.1 - 5.9e-09 35.4 0.0 1.7e-07 30.6 0.0 2.2 2 0 0 2 2 2 1 NAD synthase Asn_synthase PF00733.21 EHU01168.1 - 1.1e-06 28.6 0.0 1.4e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase ThiI PF02568.14 EHU01168.1 - 4.4e-06 26.4 0.0 6.8e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 EHU01168.1 - 0.00043 19.9 0.0 0.0012 18.4 0.0 1.8 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 EHU01168.1 - 0.14 11.9 0.1 0.32 10.7 0.1 1.7 1 1 0 1 1 1 0 PP-loop family PseudoU_synth_2 PF00849.22 EHU01169.1 - 4.2e-13 49.7 1.1 3.3e-11 43.5 0.0 2.9 2 1 0 2 2 2 1 RNA pseudouridylate synthase DUF5350 PF17299.2 EHU01169.1 - 0.63 10.6 3.9 39 4.8 0.0 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5350) Iso_dh PF00180.20 EHU01170.1 - 6.1e-117 390.7 0.0 7e-117 390.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase tRNA_synt_1c_R1 PF04558.15 EHU01170.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Arm-DNA-bind_1 PF09003.10 EHU01171.1 - 4.6e-33 113.2 0.1 8.4e-33 112.4 0.1 1.5 1 0 0 1 1 1 1 Bacteriophage lambda integrase, Arm DNA-binding domain Phage_integrase PF00589.22 EHU01171.1 - 9.2e-20 71.1 1.0 1.2e-19 70.8 0.2 1.6 2 0 0 2 2 2 1 Phage integrase family Arm-DNA-bind_3 PF13356.6 EHU01171.1 - 0.067 13.6 0.0 0.19 12.1 0.0 1.8 1 0 0 1 1 1 0 Arm DNA-binding domain DUF4942 PF13708.6 EHU01173.1 - 1.1e-22 80.9 0.0 1.6e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4942) MTS PF05175.14 EHU01173.1 - 4.5e-05 23.1 0.0 8.2e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Not3 PF04065.15 EHU01174.1 - 0.04 13.4 0.0 0.047 13.1 0.0 1.1 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component HTH_Crp_2 PF13545.6 EHU01174.1 - 0.08 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Sigma70_r4_2 PF08281.12 EHU01175.1 - 0.00017 21.2 0.1 0.00078 19.1 0.0 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_24 PF13412.6 EHU01175.1 - 0.0029 17.1 0.0 0.012 15.2 0.0 2.0 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_7 PF02796.15 EHU01175.1 - 0.011 15.8 0.1 0.024 14.7 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_38 PF13936.6 EHU01175.1 - 0.059 13.1 1.4 2.4 8.0 0.1 2.6 2 1 0 2 2 2 0 Helix-turn-helix domain Sigma70_r3 PF04539.16 EHU01175.1 - 0.15 12.2 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-70 region 3 FlbD PF06289.11 EHU01178.1 - 0.00016 21.2 0.5 0.00023 20.7 0.5 1.2 1 0 0 1 1 1 1 Flagellar and Swarming motility proteins Sipho_Gp157 PF05565.11 EHU01180.1 - 1.3e-29 103.3 1.3 8.6e-29 100.6 1.5 1.8 2 0 0 2 2 2 1 Siphovirus Gp157 ERM PF00769.19 EHU01180.1 - 0.00015 21.6 1.4 0.00021 21.2 1.4 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family LPP PF04728.13 EHU01180.1 - 0.0095 16.3 1.2 0.11 12.9 0.1 2.5 2 0 0 2 2 2 1 Lipoprotein leucine-zipper KfrA_N PF11740.8 EHU01180.1 - 0.043 14.5 2.4 0.41 11.3 0.0 2.3 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term TipAS PF07739.13 EHU01180.1 - 0.057 14.0 0.4 1.1 9.8 0.0 2.2 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Jnk-SapK_ap_N PF09744.9 EHU01180.1 - 0.065 13.5 0.7 0.35 11.1 0.1 2.0 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Tropomyosin_1 PF12718.7 EHU01180.1 - 0.11 12.7 0.4 0.11 12.7 0.4 1.8 2 0 0 2 2 2 0 Tropomyosin like PP-binding_2 PF14573.6 EHU01180.1 - 0.11 12.7 0.1 0.6 10.4 0.0 1.9 2 0 0 2 2 2 0 Acyl-carrier Seryl_tRNA_N PF02403.22 EHU01180.1 - 0.6 10.4 3.6 3.6 7.9 0.3 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Rad52_Rad22 PF04098.15 EHU01181.1 - 0.03 14.2 0.0 0.071 13.0 0.0 1.6 1 0 0 1 1 1 0 Rad52/22 family double-strand break repair protein Fe_dep_repress PF01325.19 EHU01182.1 - 0.018 15.2 0.0 0.035 14.3 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain DUF1482 PF07358.11 EHU01183.1 - 2.6e-15 56.1 0.1 2.8e-15 56.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1482) IL2 PF00715.17 EHU01184.1 - 0.077 12.9 0.1 0.093 12.7 0.1 1.2 1 0 0 1 1 1 0 Interleukin 2 TnpB_IS66 PF05717.13 EHU01185.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHU01186.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU01186.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU01186.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU01186.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix DDE_3 PF13358.6 EHU01187.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHU01187.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHU01187.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHU01187.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHU01187.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHU01187.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHU01187.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHU01187.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 Lyase_aromatic PF00221.19 EHU01188.1 - 9.3e-114 380.6 3.0 1.1e-113 380.4 3.0 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase Urocanase_C PF17392.2 EHU01189.1 - 2.7e-92 307.6 0.0 4.5e-92 306.9 0.0 1.4 1 0 0 1 1 1 1 Urocanase C-terminal domain Urocanase PF01175.18 EHU01189.1 - 9.6e-83 277.0 0.0 1.3e-82 276.6 0.0 1.2 1 0 0 1 1 1 1 Urocanase Rossmann-like domain Urocanase_N PF17391.2 EHU01189.1 - 6.2e-61 203.7 0.0 1e-60 203.0 0.0 1.3 1 0 0 1 1 1 1 Urocanase N-terminal domain Peptidase_M20 PF01546.28 EHU01190.1 - 1.2e-32 113.3 0.1 1.7e-32 112.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EHU01190.1 - 2.9e-12 46.5 0.0 5.9e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EHU01190.1 - 0.094 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 Glycos_trans_3N PF02885.17 EHU01191.1 - 9.9e-09 34.9 0.2 6.5e-08 32.3 0.1 2.3 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain Glycos_transf_3 PF00591.21 EHU01191.1 - 3.7e-05 23.4 0.0 0.00011 21.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family, a/b domain DUF4232 PF14016.6 EHU01191.1 - 0.087 13.0 0.1 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) Helicase_C_2 PF13307.6 EHU01192.1 - 5.6e-25 88.5 0.0 1.1e-24 87.6 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD PF00270.29 EHU01192.1 - 1.1e-07 31.8 0.0 3.3e-05 23.7 0.0 3.0 3 0 0 3 3 3 2 DEAD/DEAH box helicase DEAD_2 PF06733.15 EHU01192.1 - 1.5e-06 27.9 0.0 2.9e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 EHU01192.1 - 1.5e-06 28.3 0.0 5.3e-05 23.3 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EHU01192.1 - 0.13 12.5 0.1 11 6.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain Acetyltransf_1 PF00583.25 EHU01193.1 - 2.5e-14 53.5 0.0 3.9e-14 52.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EHU01193.1 - 2.8e-12 46.7 0.1 4.9e-12 45.9 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EHU01193.1 - 9.7e-09 35.5 0.1 2.7e-08 34.1 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EHU01193.1 - 1.2e-07 31.9 0.0 1.6e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EHU01193.1 - 2.6e-06 27.3 0.1 6.4e-06 26.1 0.1 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EHU01193.1 - 1.6e-05 25.0 0.1 2.8e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 EHU01193.1 - 0.00088 19.2 0.2 0.0027 17.6 0.1 2.0 2 1 1 3 3 3 1 ESCO1/2 acetyl-transferase PanZ PF12568.8 EHU01193.1 - 0.019 14.7 0.5 0.026 14.2 0.5 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_4 PF13420.7 EHU01193.1 - 0.082 13.0 0.0 0.099 12.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HTH_3 PF01381.22 EHU01194.1 - 8.4e-13 48.2 0.2 1.2e-12 47.6 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EHU01194.1 - 2.4e-12 47.0 3.4 3.9e-12 46.3 3.4 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 EHU01194.1 - 1.1e-08 35.0 0.0 1.5e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 EHU01194.1 - 2.3e-07 31.1 0.2 3.4e-07 30.6 0.2 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 EHU01194.1 - 1.2e-05 25.0 0.3 2.2e-05 24.2 0.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 EHU01194.1 - 0.00096 18.9 0.3 0.0018 18.0 0.3 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_37 PF13744.6 EHU01194.1 - 0.0039 17.1 0.1 0.0064 16.4 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Cupin_2 PF07883.11 EHU01194.1 - 0.006 16.3 0.0 0.0093 15.7 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Sigma70_r4 PF04545.16 EHU01194.1 - 0.044 13.3 0.1 0.08 12.5 0.1 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_IclR PF09339.10 EHU01194.1 - 0.071 12.9 0.1 0.19 11.6 0.1 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain GntR PF00392.21 EHU01194.1 - 0.076 12.7 0.1 1.5 8.5 0.1 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_28 PF13518.6 EHU01194.1 - 0.13 12.4 0.1 0.97 9.6 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_AraC PF00165.23 EHU01194.1 - 0.16 12.1 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_Crp_2 PF13545.6 EHU01194.1 - 0.37 10.8 2.2 0.44 10.5 1.0 1.8 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain MerR_1 PF13411.6 EHU01195.1 - 5.9e-19 67.9 0.1 2.9e-18 65.7 0.0 2.0 2 0 0 2 2 2 1 MerR HTH family regulatory protein MerR PF00376.23 EHU01195.1 - 1.1e-13 50.7 0.0 2.5e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 MerR family regulatory protein HTH_17 PF12728.7 EHU01195.1 - 9e-06 25.8 0.1 4.4e-05 23.6 0.0 2.2 2 1 0 2 2 2 1 Helix-turn-helix domain MerR_2 PF13591.6 EHU01195.1 - 0.00039 20.2 0.0 0.00078 19.3 0.0 1.5 1 0 0 1 1 1 1 MerR HTH family regulatory protein HTH_Tnp_1 PF01527.20 EHU01195.1 - 0.0012 19.1 0.4 0.0041 17.4 0.0 2.1 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.6 EHU01195.1 - 0.005 16.6 0.0 0.02 14.7 0.0 2.0 1 0 0 1 1 1 1 Homeodomain-like domain Terminase_5 PF06056.12 EHU01195.1 - 0.0089 15.9 0.0 0.031 14.2 0.0 1.9 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) HTH_28 PF13518.6 EHU01195.1 - 0.014 15.6 0.1 0.065 13.4 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain BPD_transp_1 PF00528.22 EHU01196.1 - 7.3e-26 91.0 12.4 7.3e-26 91.0 12.4 2.0 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 EHU01197.1 - 5.8e-33 114.3 0.0 8.1e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter CBS PF00571.28 EHU01197.1 - 8.1e-07 29.4 0.0 1.9e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 CBS domain AAA_21 PF13304.6 EHU01197.1 - 1.3e-05 25.2 0.0 0.059 13.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EHU01197.1 - 2.4e-05 24.1 0.0 3.8e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EHU01197.1 - 0.0035 17.3 0.0 0.006 16.5 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 EHU01197.1 - 0.0079 16.5 0.0 0.12 12.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 EHU01197.1 - 0.0083 15.6 0.2 1.1 8.6 0.2 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain G-alpha PF00503.20 EHU01197.1 - 0.01 15.0 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_29 PF13555.6 EHU01197.1 - 0.013 15.2 0.1 0.025 14.3 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EHU01197.1 - 0.015 15.7 0.8 0.044 14.2 0.3 2.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 EHU01197.1 - 0.14 12.7 0.0 0.22 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EHU01197.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 EHU01197.1 - 0.2 10.9 0.0 0.32 10.2 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin BPD_transp_1 PF00528.22 EHU01198.1 - 9.9e-20 71.0 18.3 9.9e-20 71.0 18.3 2.8 2 2 1 3 3 3 1 Binding-protein-dependent transport system inner membrane component OpuAC PF04069.12 EHU01199.1 - 1e-58 198.9 6.1 1.2e-58 198.8 6.1 1.0 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system NUDIX PF00293.28 EHU01200.1 - 8.3e-21 74.4 0.0 1e-20 74.1 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Homeobox_KN PF05920.11 EHU01200.1 - 0.041 13.8 0.0 0.44 10.5 0.0 2.6 2 1 0 2 2 2 0 Homeobox KN domain MCPsignal PF00015.21 EHU01201.1 - 7.9e-51 172.3 19.6 7.9e-51 172.3 19.6 3.7 2 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain dCache_1 PF02743.18 EHU01201.1 - 1.1e-27 97.4 0.0 1.1e-27 97.4 0.0 3.0 3 1 1 4 4 4 1 Cache domain HAMP PF00672.25 EHU01201.1 - 2.2e-08 34.3 0.3 1.2e-06 28.8 0.0 3.3 2 0 0 2 2 2 1 HAMP domain Afaf PF15339.6 EHU01201.1 - 0.01 15.5 0.6 0.019 14.7 0.1 1.7 2 0 0 2 2 2 0 Acrosome formation-associated factor DUF4788 PF16032.5 EHU01201.1 - 0.018 14.0 0.0 0.037 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4788) SUFU PF05076.13 EHU01202.1 - 2.1e-21 76.7 0.1 3.3e-21 76.0 0.1 1.2 1 0 0 1 1 1 1 Suppressor of fused protein (SUFU) Glyco_hydro_3 PF00933.21 EHU01203.1 - 3.4e-95 319.1 0.0 5.4e-95 318.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EHU01203.1 - 2.9e-60 203.7 0.1 4.9e-60 203.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 EHU01203.1 - 7.7e-23 80.4 0.0 1.5e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Sugar-bind PF04198.13 EHU01203.1 - 0.01 15.0 0.1 0.021 13.9 0.1 1.5 1 0 0 1 1 1 0 Putative sugar-binding domain Alanine_zipper PF11839.8 EHU01203.1 - 0.19 12.1 1.4 0.43 11.0 1.4 1.6 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein Lact-deh-memb PF09330.11 EHU01204.1 - 5.1e-144 479.0 0.3 6.2e-144 478.7 0.3 1.1 1 0 0 1 1 1 1 D-lactate dehydrogenase, membrane binding FAD_binding_4 PF01565.23 EHU01204.1 - 2.1e-07 30.7 0.0 3.9e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Herpes_glycop PF01528.16 EHU01204.1 - 0.19 10.5 0.1 0.32 9.8 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein M MS_channel PF00924.18 EHU01205.1 - 2.6e-40 138.2 8.0 3.1e-40 137.9 5.4 2.4 2 0 0 2 2 2 1 Mechanosensitive ion channel DUF3772 PF12607.8 EHU01205.1 - 3.3e-19 68.4 0.9 9.7e-19 66.9 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3772) Zn_peptidase_2 PF04298.12 EHU01205.1 - 0.0022 17.4 0.8 0.0022 17.4 0.8 2.1 2 0 0 2 2 2 1 Putative neutral zinc metallopeptidase Peptidase_S11 PF00768.20 EHU01206.1 - 2.2e-75 253.2 0.2 2.6e-75 252.9 0.2 1.1 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 EHU01206.1 - 1.4e-08 34.6 0.1 1.8e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase enzyme family Beta-lactamase PF00144.24 EHU01206.1 - 0.0065 15.8 0.1 0.05 12.9 0.0 2.1 2 0 0 2 2 2 1 Beta-lactamase Peptidase_S13 PF02113.15 EHU01206.1 - 0.022 13.5 0.5 0.55 8.9 0.1 2.1 2 0 0 2 2 2 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family DUF1282 PF06930.12 EHU01207.1 - 2.9e-37 128.1 4.1 3.4e-37 127.9 4.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) Yip1 PF04893.17 EHU01207.1 - 1.3e-27 96.6 7.1 1.3e-27 96.6 7.1 1.5 1 1 0 1 1 1 1 Yip1 domain B12D PF06522.11 EHU01207.1 - 0.38 10.6 3.5 1.4 8.8 3.5 2.0 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit SNARE_assoc PF09335.11 EHU01208.1 - 4e-19 69.3 5.8 4e-19 69.3 5.8 1.6 2 1 0 2 2 2 1 SNARE associated Golgi protein CPP1-like PF11833.8 EHU01208.1 - 0.16 11.6 1.7 0.3 10.7 1.7 1.4 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like RseC_MucC PF04246.12 EHU01208.1 - 0.61 10.0 2.6 14 5.7 0.5 2.3 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Mor PF08765.11 EHU01209.1 - 3.5e-33 113.8 0.0 4.2e-33 113.6 0.0 1.0 1 0 0 1 1 1 1 Mor transcription activator family Sigma70_r4_2 PF08281.12 EHU01209.1 - 0.14 11.8 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 DUF1018 PF06252.12 EHU01210.1 - 1.9e-40 138.5 1.6 2.3e-40 138.3 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1018) PPR_2 PF13041.6 EHU01210.1 - 0.055 13.7 0.1 6.1 7.1 0.0 3.0 4 0 0 4 4 4 0 PPR repeat family DUF3368 PF11848.8 EHU01210.1 - 0.088 12.6 0.0 0.39 10.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3368) DUF2786 PF10979.8 EHU01212.1 - 8.2e-12 44.8 5.1 1.3e-11 44.2 5.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2786) PRA-PH PF01503.17 EHU01213.1 - 0.0037 17.7 0.1 0.0041 17.5 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 EHU01213.1 - 0.081 13.1 0.3 0.12 12.6 0.3 1.3 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain Cellulase PF00150.18 EHU01213.1 - 0.2 11.0 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) zf-LITAF-like PF10601.9 EHU01214.1 - 0.02 15.1 4.9 0.38 11.1 0.5 2.2 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain CxC5 PF18718.1 EHU01214.1 - 0.02 14.9 3.5 0.03 14.4 3.5 1.3 1 1 0 1 1 1 0 CxC5 like cysteine cluster associated with KDZ transposases zf-ribbon_3 PF13248.6 EHU01214.1 - 0.03 13.7 2.2 1.5 8.4 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Ribosomal_L33 PF00471.20 EHU01214.1 - 0.037 14.5 0.5 0.65 10.5 0.1 2.1 2 0 0 2 2 2 0 Ribosomal protein L33 zinc_ribbon_4 PF13717.6 EHU01214.1 - 0.048 13.6 4.9 2.1 8.4 0.8 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf_UBZ PF18439.1 EHU01214.1 - 0.097 12.3 1.7 11 5.7 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DUF3164 PF11363.8 EHU01215.1 - 1.2e-85 286.1 0.9 1.3e-85 285.9 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3164) Mu-like_Com PF10122.9 EHU01216.1 - 0.12 11.9 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 Mu-like prophage protein Com AAA_22 PF13401.6 EHU01217.1 - 2e-17 63.8 0.0 6.1e-17 62.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EHU01217.1 - 9e-05 22.9 1.9 0.00028 21.3 0.3 2.4 2 1 0 2 2 2 1 AAA ATPase domain DUF87 PF01935.17 EHU01217.1 - 0.00061 19.9 0.0 0.002 18.3 0.0 1.8 2 0 0 2 2 2 1 Helicase HerA, central domain ABC_tran PF00005.27 EHU01217.1 - 0.00084 19.9 0.1 0.0021 18.6 0.1 1.6 1 1 0 1 1 1 1 ABC transporter Helicase_RecD PF05127.14 EHU01217.1 - 0.0044 16.9 0.1 0.0082 16.0 0.1 1.4 1 0 0 1 1 1 1 Helicase AAA_30 PF13604.6 EHU01217.1 - 0.005 16.6 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain PRK PF00485.18 EHU01217.1 - 0.0074 16.1 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.6 EHU01217.1 - 0.015 15.0 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EHU01217.1 - 0.016 15.1 0.0 0.06 13.3 0.0 1.9 1 1 0 2 2 2 0 RsgA GTPase ATP-synt_ab PF00006.25 EHU01217.1 - 0.017 14.8 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.29 EHU01217.1 - 0.017 15.5 0.1 0.38 11.2 0.1 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EHU01217.1 - 0.021 15.0 0.1 0.23 11.6 0.0 2.6 3 1 0 3 3 3 0 AAA domain MEDS PF14417.6 EHU01217.1 - 0.028 14.2 0.1 1.4 8.7 0.0 2.9 3 1 0 3 3 3 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain MMR_HSR1 PF01926.23 EHU01217.1 - 0.034 14.2 0.0 0.092 12.8 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.14 EHU01217.1 - 0.073 13.0 0.0 0.3 11.0 0.0 2.1 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Sigma54_activat PF00158.26 EHU01217.1 - 0.085 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain HAD_SAK_2 PF18143.1 EHU01217.1 - 0.092 13.1 0.1 0.51 10.6 0.1 2.2 2 1 0 2 2 2 0 HAD domain in Swiss Army Knife RNA repair proteins AAA_5 PF07728.14 EHU01217.1 - 0.093 12.7 0.1 1 9.3 0.0 2.9 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 EHU01217.1 - 0.097 12.4 0.0 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ATPase_2 PF01637.18 EHU01217.1 - 0.12 12.3 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea HTH_31 PF13560.6 EHU01217.1 - 0.12 12.7 0.5 0.33 11.3 0.5 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain AAA_18 PF13238.6 EHU01217.1 - 0.12 12.9 0.1 0.3 11.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain CUT PF02376.15 EHU01217.1 - 0.13 12.5 0.0 0.44 10.7 0.0 1.9 2 0 0 2 2 1 0 CUT domain NB-ARC PF00931.22 EHU01217.1 - 0.17 11.0 0.0 0.35 10.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain rve PF00665.26 EHU01218.1 - 1.1e-12 48.2 0.0 2.7e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain HTH_8 PF02954.19 EHU01218.1 - 0.0032 17.2 1.3 0.012 15.4 0.1 2.6 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family HTH_23 PF13384.6 EHU01218.1 - 0.041 13.7 0.1 2 8.3 0.1 2.7 2 0 0 2 2 2 0 Homeodomain-like domain DUF3102 PF11300.8 EHU01219.1 - 3.8e-07 30.4 0.2 7.6e-07 29.4 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3102) Atg14 PF10186.9 EHU01219.1 - 0.11 11.6 1.4 0.17 10.9 1.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMF_DNA_bd PF12329.8 EHU01219.1 - 0.31 11.1 7.8 1.8 8.6 4.3 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding BST2 PF16716.5 EHU01219.1 - 0.85 10.2 4.2 0.34 11.5 1.0 1.9 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 DUF1690 PF07956.11 EHU01219.1 - 0.89 10.0 5.3 0.71 10.3 3.1 1.9 3 0 0 3 3 3 0 Protein of Unknown function (DUF1690) HTH_IclR PF09339.10 EHU01220.1 - 9.3e-06 25.4 0.2 1.7e-05 24.5 0.2 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 EHU01220.1 - 0.0003 20.6 0.1 0.0005 19.9 0.1 1.3 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 EHU01220.1 - 0.0005 19.6 0.2 0.0014 18.2 0.2 1.7 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 EHU01220.1 - 0.0028 17.6 0.1 0.0061 16.5 0.1 1.7 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain MarR PF01047.22 EHU01220.1 - 0.0037 17.2 0.0 0.0059 16.5 0.0 1.4 1 1 0 1 1 1 1 MarR family HTH_20 PF12840.7 EHU01220.1 - 0.0068 16.4 0.2 0.011 15.8 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 EHU01220.1 - 0.017 15.0 0.1 0.033 14.1 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family GntR PF00392.21 EHU01220.1 - 0.019 14.6 0.1 0.11 12.2 0.0 2.1 1 1 1 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_11 PF08279.12 EHU01220.1 - 0.046 13.7 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 HTH domain SBP_bac_11 PF13531.6 EHU01220.1 - 0.063 13.0 0.0 0.071 12.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein RPA_C PF08784.11 EHU01220.1 - 0.074 13.7 0.1 0.16 12.7 0.0 1.5 2 0 0 2 2 2 0 Replication protein A C terminal MethyltransfD12 PF02086.15 EHU01222.1 - 2.4e-25 89.7 0.0 3e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase DDE_3 PF13358.6 EHU01223.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHU01223.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHU01223.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.6 EHU01223.1 - 4.5e-06 26.6 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_33 PF13592.6 EHU01223.1 - 7.2e-05 22.4 0.5 7.2e-05 22.4 0.5 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_28 PF13518.6 EHU01223.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHU01223.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHU01223.1 - 0.097 13.2 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 CSD PF00313.22 EHU01224.1 - 8.3e-28 96.0 0.1 9.3e-28 95.9 0.1 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain S1 PF00575.23 EHU01224.1 - 0.066 13.6 0.0 0.076 13.4 0.0 1.2 1 0 0 1 1 1 0 S1 RNA binding domain OB_RNB PF08206.11 EHU01224.1 - 0.078 12.7 0.1 0.098 12.3 0.1 1.3 1 0 0 1 1 1 0 Ribonuclease B OB domain ClpS PF02617.17 EHU01225.1 - 1.8e-33 114.2 0.1 2.1e-33 114.0 0.1 1.1 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS ExbD PF02472.16 EHU01225.1 - 0.11 12.6 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR AAA_2 PF07724.14 EHU01226.1 - 7.8e-52 175.8 0.0 5.7e-48 163.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EHU01226.1 - 3.7e-30 103.9 1.5 1.1e-29 102.5 1.5 1.8 1 0 0 1 1 1 1 AAA lid domain ClpB_D2-small PF10431.9 EHU01226.1 - 5.5e-25 87.2 0.0 1.8e-24 85.5 0.0 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EHU01226.1 - 1.2e-23 84.0 0.1 2.1e-12 47.6 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EHU01226.1 - 2.5e-18 66.4 0.0 2.8e-12 46.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 EHU01226.1 - 3.9e-16 58.9 1.0 9.9e-15 54.4 0.9 2.9 2 0 0 2 2 2 1 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 EHU01226.1 - 1.2e-11 45.3 6.1 3.8e-06 27.4 0.2 4.1 4 1 0 4 4 3 2 AAA ATPase domain Sigma54_activat PF00158.26 EHU01226.1 - 4.1e-11 42.9 0.1 0.00014 21.6 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain TniB PF05621.11 EHU01226.1 - 1.1e-10 41.3 0.0 1.4e-07 31.1 0.0 3.7 2 2 1 3 3 3 1 Bacterial TniB protein AAA_22 PF13401.6 EHU01226.1 - 3e-07 30.8 4.9 0.045 14.0 0.1 4.7 2 2 1 3 3 3 2 AAA domain ResIII PF04851.15 EHU01226.1 - 7.1e-07 29.4 0.0 0.021 14.8 0.0 3.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit RuvB_N PF05496.12 EHU01226.1 - 1.9e-06 27.7 0.3 0.39 10.4 0.0 4.4 4 0 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 EHU01226.1 - 4.8e-06 26.6 0.0 0.0074 16.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EHU01226.1 - 2.1e-05 24.1 0.0 0.24 10.9 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 EHU01226.1 - 2.5e-05 24.8 0.2 0.051 14.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 EHU01226.1 - 3.2e-05 23.7 0.0 0.067 12.9 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein TIP49 PF06068.13 EHU01226.1 - 5.7e-05 22.5 0.2 0.37 9.9 0.0 2.8 3 0 0 3 3 2 2 TIP49 P-loop domain AAA_6 PF12774.7 EHU01226.1 - 0.0002 20.4 0.0 0.00048 19.2 0.0 1.6 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_25 PF13481.6 EHU01226.1 - 0.00022 20.9 0.6 0.34 10.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_3 PF07726.11 EHU01226.1 - 0.00022 21.1 0.1 0.0031 17.4 0.1 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EHU01226.1 - 0.00036 20.7 0.0 0.088 13.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 EHU01226.1 - 0.001 19.1 0.1 0.45 10.5 0.1 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EHU01226.1 - 0.0016 18.8 0.0 1.9 8.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase RsgA_GTPase PF03193.16 EHU01226.1 - 0.0025 17.7 0.0 1.3 8.9 0.0 2.8 2 0 0 2 2 2 1 RsgA GTPase Mg_chelatase PF01078.21 EHU01226.1 - 0.0036 16.7 1.6 8.9 5.6 0.0 4.1 3 2 0 4 4 4 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 EHU01226.1 - 0.0075 15.6 0.4 7.3 5.8 0.0 3.7 3 0 0 3 3 3 0 Zeta toxin CbiA PF01656.23 EHU01226.1 - 0.011 15.7 0.1 2 8.5 0.0 2.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_23 PF13476.6 EHU01226.1 - 0.019 15.5 1.8 1.5 9.3 0.1 3.3 2 1 1 3 3 3 0 AAA domain AAA_29 PF13555.6 EHU01226.1 - 0.019 14.7 0.0 3.1 7.6 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain NACHT PF05729.12 EHU01226.1 - 0.029 14.3 0.7 0.3 11.0 0.0 2.7 3 0 0 3 3 3 0 NACHT domain IPT PF01745.16 EHU01226.1 - 0.035 13.5 0.0 0.14 11.5 0.0 2.0 2 0 0 2 2 2 0 Isopentenyl transferase DNA_pol3_delta2 PF13177.6 EHU01226.1 - 0.039 13.7 0.1 2.5 7.9 0.0 3.6 4 0 0 4 4 4 0 DNA polymerase III, delta subunit Rad17 PF03215.15 EHU01226.1 - 0.046 13.6 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain SRP54 PF00448.22 EHU01226.1 - 0.069 12.8 0.2 8.4 6.0 0.2 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DEAD PF00270.29 EHU01226.1 - 0.076 12.8 0.9 14 5.4 0.0 3.4 3 1 0 3 3 3 0 DEAD/DEAH box helicase Hpr_kinase_C PF07475.12 EHU01226.1 - 0.1 12.1 0.0 14 5.1 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain ParA PF10609.9 EHU01226.1 - 0.13 11.7 0.1 10 5.5 0.0 2.4 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase eIF-1a PF01176.19 EHU01227.1 - 2.7e-27 94.3 0.0 3e-27 94.2 0.0 1.0 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 RsgA_N PF16745.5 EHU01227.1 - 3.8e-05 23.3 0.0 4.6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 RsgA N-terminal domain RNase_II_C_S1 PF18614.1 EHU01227.1 - 0.013 15.5 0.0 0.033 14.1 0.0 1.9 1 1 0 1 1 1 0 RNase II-type exonuclease C-terminal S1 domain S1 PF00575.23 EHU01227.1 - 0.02 15.2 0.1 0.024 15.0 0.1 1.2 1 0 0 1 1 1 0 S1 RNA binding domain Myosin_N PF02736.19 EHU01227.1 - 0.09 12.6 0.0 5.2 7.0 0.0 2.3 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain Leu_Phe_trans PF03588.14 EHU01228.1 - 3e-69 231.9 0.0 3.5e-69 231.7 0.0 1.0 1 0 0 1 1 1 1 Leucyl/phenylalanyl-tRNA protein transferase ABC_tran PF00005.27 EHU01229.1 - 1.4e-30 106.6 0.0 2.7e-30 105.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EHU01229.1 - 1.3e-06 28.3 6.5 1.3e-06 28.3 6.5 2.5 2 1 0 2 2 2 1 ABC transporter transmembrane region AAA_30 PF13604.6 EHU01229.1 - 4.6e-06 26.5 0.1 1.4e-05 24.9 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EHU01229.1 - 0.00052 20.4 0.1 0.00052 20.4 0.1 2.8 2 1 1 3 3 3 1 AAA ATPase domain SMC_N PF02463.19 EHU01229.1 - 0.00062 19.3 0.0 0.019 14.4 0.0 2.0 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EHU01229.1 - 0.00095 19.1 0.1 1.1 9.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 EHU01229.1 - 0.0023 17.9 0.0 0.0053 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 EHU01229.1 - 0.0075 16.2 0.0 0.095 12.6 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_18 PF13238.6 EHU01229.1 - 0.0079 16.7 0.0 0.023 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EHU01229.1 - 0.01 15.8 1.9 0.032 14.1 0.0 2.5 3 0 0 3 3 3 0 NACHT domain AAA_25 PF13481.6 EHU01229.1 - 0.012 15.2 0.0 0.077 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EHU01229.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 EHU01229.1 - 0.025 14.8 0.8 0.34 11.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EHU01229.1 - 0.026 14.2 0.0 0.078 12.7 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF5337 PF17272.2 EHU01229.1 - 0.031 14.1 1.5 0.11 12.3 1.5 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5337) AAA_22 PF13401.6 EHU01229.1 - 0.052 13.8 0.0 0.17 12.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.17 EHU01229.1 - 0.12 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 EHU01229.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 EHU01229.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.6 EHU01229.1 - 0.15 12.5 0.6 0.92 10.0 0.1 2.0 2 0 0 2 2 2 0 AAA domain DUF1129 PF06570.11 EHU01229.1 - 0.16 11.4 0.1 0.16 11.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) AAA_7 PF12775.7 EHU01229.1 - 0.19 11.2 0.0 0.77 9.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF4337 PF14235.6 EHU01229.1 - 0.68 10.0 4.8 0.67 10.1 2.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) DUF2207 PF09972.9 EHU01229.1 - 0.88 8.3 0.0 0.88 8.3 0.0 2.7 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) ABC_membrane PF00664.23 EHU01230.1 - 6.2e-37 127.7 3.3 8.8e-37 127.2 3.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EHU01230.1 - 9.9e-27 94.1 0.0 1.6e-26 93.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EHU01230.1 - 4.2e-06 26.3 0.1 0.0014 18.1 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EHU01230.1 - 1.6e-05 24.9 5.9 0.0084 15.9 0.2 2.5 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EHU01230.1 - 0.001 19.3 0.7 0.0049 17.2 0.1 2.4 2 1 0 2 2 1 1 AAA domain RsgA_GTPase PF03193.16 EHU01230.1 - 0.002 18.1 0.0 0.0041 17.0 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 EHU01230.1 - 0.0058 16.7 0.2 0.015 15.4 0.1 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase IstB_IS21 PF01695.17 EHU01230.1 - 0.011 15.4 1.0 2 8.1 0.1 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_29 PF13555.6 EHU01230.1 - 0.021 14.5 0.0 0.052 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EHU01230.1 - 0.035 14.5 0.5 0.035 14.5 0.5 2.3 2 2 0 2 2 2 0 AAA ATPase domain MobB PF03205.14 EHU01230.1 - 0.072 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AIG1 PF04548.16 EHU01230.1 - 0.081 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 AIG1 family Pox_A32 PF04665.12 EHU01230.1 - 0.087 12.3 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein Dynamin_N PF00350.23 EHU01230.1 - 0.11 12.6 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Dynamin family AAA_7 PF12775.7 EHU01230.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Roc PF08477.13 EHU01230.1 - 0.18 12.0 0.0 1.2 9.4 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 EHU01230.1 - 0.27 11.7 0.0 0.46 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Pyr_redox_2 PF07992.14 EHU01231.1 - 5.1e-52 176.9 0.3 5.9e-52 176.7 0.3 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EHU01231.1 - 3.6e-22 79.0 0.1 7.5e-18 64.8 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EHU01231.1 - 3.1e-18 66.1 2.4 1.9e-17 63.6 1.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EHU01231.1 - 4e-07 29.4 2.8 0.062 12.4 0.1 3.9 4 0 0 4 4 4 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EHU01231.1 - 5.8e-05 22.4 6.6 0.01 15.0 0.2 3.7 2 1 0 4 4 4 2 FAD binding domain HI0933_like PF03486.14 EHU01231.1 - 6.9e-05 21.7 0.3 1.1 7.9 0.1 4.3 4 1 1 5 5 5 1 HI0933-like protein DAO PF01266.24 EHU01231.1 - 0.00018 21.2 0.7 1 8.9 0.0 3.5 3 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EHU01231.1 - 0.00078 18.9 0.2 0.0022 17.4 0.0 1.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EHU01231.1 - 0.0012 19.0 0.0 0.0057 16.8 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EHU01231.1 - 0.0015 17.8 0.1 0.02 14.1 0.0 2.2 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 EHU01231.1 - 0.029 14.4 0.2 1.8 8.6 0.0 3.1 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EHU01231.1 - 0.03 14.8 0.0 0.27 11.7 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding Thi4 PF01946.17 EHU01231.1 - 0.034 13.4 0.9 0.6 9.3 0.0 2.7 2 1 1 3 3 3 0 Thi4 family AlaDh_PNT_C PF01262.21 EHU01231.1 - 0.051 12.9 0.1 3.9 6.7 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 EHU01231.1 - 0.081 11.8 0.6 0.67 8.7 0.1 2.3 3 0 0 3 3 3 0 Tryptophan halogenase FMO-like PF00743.19 EHU01231.1 - 0.11 10.9 0.0 0.15 10.4 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like AsnC_trans_reg PF01037.21 EHU01232.1 - 6.3e-24 83.7 0.1 1.8e-23 82.3 0.0 1.7 2 0 0 2 2 2 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 EHU01232.1 - 2.2e-21 75.1 0.3 6.5e-21 73.6 0.3 1.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 EHU01232.1 - 5.4e-20 71.0 0.4 8.4e-20 70.3 0.4 1.3 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain MarR PF01047.22 EHU01232.1 - 0.0068 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 EHU01232.1 - 0.026 14.4 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 MarR family LexA_DNA_bind PF01726.16 EHU01232.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 LexA DNA binding domain FtsK_SpoIIIE PF01580.18 EHU01233.1 - 3.5e-73 246.0 0.0 5.7e-73 245.2 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family FtsK_4TM PF13491.6 EHU01233.1 - 3.1e-44 150.7 13.4 4.5e-44 150.2 13.4 1.3 1 0 0 1 1 1 1 4TM region of DNA translocase FtsK/SpoIIIE FtsK_alpha PF17854.1 EHU01233.1 - 3e-28 97.9 0.0 5.6e-28 97.0 0.0 1.5 1 0 0 1 1 1 1 FtsK alpha domain FtsK_gamma PF09397.10 EHU01233.1 - 8.9e-28 95.9 0.1 1.7e-27 95.0 0.1 1.5 1 0 0 1 1 1 1 Ftsk gamma domain AAA_10 PF12846.7 EHU01233.1 - 2e-05 23.7 0.0 0.0027 16.7 0.0 2.2 2 0 0 2 2 2 2 AAA-like domain DUF87 PF01935.17 EHU01233.1 - 0.00026 21.2 0.1 0.00056 20.1 0.1 1.5 1 0 0 1 1 1 1 Helicase HerA, central domain T2SSE PF00437.20 EHU01233.1 - 0.016 14.3 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein TniB PF05621.11 EHU01233.1 - 0.022 14.2 0.0 15 4.9 0.0 3.2 3 0 0 3 3 3 0 Bacterial TniB protein TrwB_AAD_bind PF10412.9 EHU01233.1 - 0.025 13.5 1.2 0.28 10.1 0.0 2.5 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Adeno_IVa2 PF02456.15 EHU01233.1 - 0.06 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein HTH_Tnp_ISL3 PF13542.6 EHU01233.1 - 0.65 9.4 0.0 0.65 9.4 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 LolA PF03548.15 EHU01234.1 - 9.5e-59 197.8 4.0 1.1e-58 197.6 4.0 1.0 1 0 0 1 1 1 1 Outer membrane lipoprotein carrier protein LolA DUF2092 PF09865.9 EHU01234.1 - 3.8e-05 23.1 0.3 0.033 13.5 0.0 2.3 2 1 0 2 2 2 2 Predicted periplasmic protein (DUF2092) Cuticle_1 PF08140.11 EHU01234.1 - 0.19 11.8 1.2 10 6.3 0.0 3.3 3 1 1 4 4 4 0 Crustacean cuticle protein repeat MgsA_C PF12002.8 EHU01235.1 - 2.8e-64 216.1 0.4 5.8e-64 215.1 0.4 1.5 2 0 0 2 2 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 EHU01235.1 - 9.3e-24 83.6 0.1 3.3e-23 81.8 0.0 2.0 2 0 0 2 2 1 1 AAA C-terminal domain AAA PF00004.29 EHU01235.1 - 1.7e-16 60.8 0.1 1.3e-15 58.0 0.0 2.1 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EHU01235.1 - 2.3e-15 56.7 0.0 4.5e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EHU01235.1 - 3.5e-08 33.6 0.2 4.3e-07 30.0 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EHU01235.1 - 7.1e-07 29.8 0.3 0.02 15.3 0.0 3.4 3 1 1 4 4 3 2 AAA ATPase domain Mg_chelatase PF01078.21 EHU01235.1 - 7.5e-07 28.7 0.3 0.0017 17.8 0.1 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EHU01235.1 - 6.4e-06 26.0 0.0 0.01 15.5 0.0 2.5 1 1 1 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 EHU01235.1 - 9.3e-06 26.0 3.0 0.093 13.0 0.0 3.5 1 1 3 4 4 4 2 AAA domain AAA_19 PF13245.6 EHU01235.1 - 0.00011 22.5 0.1 0.0099 16.2 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.11 EHU01235.1 - 0.00036 20.4 0.0 0.0012 18.7 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.6 EHU01235.1 - 0.00046 20.3 0.0 0.00085 19.5 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.6 EHU01235.1 - 0.0007 19.6 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EHU01235.1 - 0.00099 18.9 0.2 0.019 14.7 0.2 2.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EHU01235.1 - 0.0012 18.6 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 EHU01235.1 - 0.0015 18.7 0.0 0.0042 17.2 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) ResIII PF04851.15 EHU01235.1 - 0.0023 18.0 0.3 0.6 10.1 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DNA_pol3_delta2 PF13177.6 EHU01235.1 - 0.0027 17.5 0.0 0.088 12.6 0.0 2.3 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_28 PF13521.6 EHU01235.1 - 0.0074 16.5 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EHU01235.1 - 0.011 16.3 0.0 0.029 14.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain DUF815 PF05673.13 EHU01235.1 - 0.018 14.2 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 EHU01235.1 - 0.019 15.5 0.0 0.035 14.6 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Parvo_NS1 PF01057.17 EHU01235.1 - 0.022 13.8 0.0 0.6 9.1 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 EHU01235.1 - 0.028 14.2 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EHU01235.1 - 0.028 14.6 0.1 0.069 13.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EHU01235.1 - 0.054 13.3 0.1 0.13 12.0 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 EHU01235.1 - 0.06 12.9 0.0 0.18 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EHU01235.1 - 0.062 12.3 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.22 EHU01235.1 - 0.073 13.5 0.0 0.43 11.0 0.0 2.2 2 0 0 2 2 2 0 RNA helicase ATP-synt_ab PF00006.25 EHU01235.1 - 0.15 11.7 0.1 0.62 9.7 0.0 2.1 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.12 EHU01235.1 - 0.16 11.9 0.1 0.79 9.6 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.6 EHU01235.1 - 0.16 12.4 0.1 0.44 11.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EHU01235.1 - 0.27 10.5 0.5 4.2 6.5 0.6 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) tRNA-synt_2b PF00587.25 EHU01236.1 - 1.2e-38 132.8 0.0 1.9e-38 132.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EHU01236.1 - 2.1e-32 111.6 2.2 3.8e-32 110.7 2.2 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Cep57_CLD_2 PF14197.6 EHU01236.1 - 0.027 14.6 6.0 0.51 10.5 4.4 2.5 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Spc7 PF08317.11 EHU01236.1 - 0.044 12.7 1.2 0.069 12.0 1.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 EHU01236.1 - 0.12 12.5 4.8 0.046 13.9 2.1 1.7 2 0 0 2 2 2 0 Tropomyosin like GAS PF13851.6 EHU01236.1 - 0.18 11.1 1.5 0.38 10.1 1.5 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ZapB PF06005.12 EHU01236.1 - 0.2 12.1 4.6 0.63 10.5 4.6 1.9 1 0 0 1 1 1 0 Cell division protein ZapB MFS_1 PF07690.16 EHU01237.1 - 2.1e-29 102.6 67.5 1.4e-19 70.3 38.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EHU01237.1 - 5.1e-14 52.4 38.4 7e-14 51.9 38.4 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 EHU01237.1 - 7.3e-07 28.4 12.0 7.3e-07 28.4 12.0 3.7 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 EHU01237.1 - 1.4e-05 24.2 7.6 1.4e-05 24.2 7.6 2.1 1 1 1 2 2 2 2 MFS_1 like family MFS_2 PF13347.6 EHU01237.1 - 1.5e-05 23.7 11.6 1.5e-05 23.7 11.6 3.0 1 1 1 3 3 3 2 MFS/sugar transport protein Radical_SAM PF04055.21 EHU01238.1 - 2.6e-30 106.0 0.1 3.4e-30 105.6 0.1 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EHU01238.1 - 6.7e-16 58.8 0.0 8.5e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EHU01238.1 - 0.00015 21.9 0.0 0.00029 20.9 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain PFL-like PF02901.15 EHU01239.1 - 1.6e-202 674.6 0.1 2.3e-202 674.1 0.1 1.1 1 0 0 1 1 1 1 Pyruvate formate lyase-like Gly_radical PF01228.21 EHU01239.1 - 8.9e-43 145.2 0.0 2.8e-42 143.6 0.0 1.9 2 0 0 2 2 2 1 Glycine radical Form_Nir_trans PF01226.17 EHU01240.1 - 1.2e-74 250.6 26.7 1.4e-74 250.4 26.7 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter HTH_Tnp_1 PF01527.20 EHU01241.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU01241.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU01241.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU01241.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHU01242.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHU01243.1 - 2.8e-97 325.6 3.9 1.2e-96 323.5 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU01243.1 - 3.4e-16 59.2 0.1 1.3e-15 57.3 0.1 2.1 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU01243.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU01243.1 - 8.8e-11 42.4 9.0 1.9e-10 41.4 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Phage_HK97_TLTM PF06120.11 EHU01243.1 - 0.029 13.6 0.7 0.056 12.6 0.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein UME PF08064.13 EHU01243.1 - 0.037 13.9 0.4 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain Exonuc_VII_L PF02601.15 EHU01243.1 - 0.041 13.4 2.5 0.044 13.4 0.9 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit FUSC PF04632.12 EHU01243.1 - 0.063 11.8 7.7 0.1 11.1 7.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Csm1_N PF18504.1 EHU01243.1 - 0.13 12.7 3.4 0.86 10.0 0.2 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Tho2 PF11262.8 EHU01243.1 - 0.17 11.0 0.3 0.28 10.4 0.3 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DHR10 PF18595.1 EHU01243.1 - 0.18 11.9 10.2 0.31 11.1 10.2 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain ERM PF00769.19 EHU01243.1 - 0.27 11.0 10.4 0.45 10.3 10.4 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family LXG PF04740.12 EHU01243.1 - 0.28 10.9 2.4 0.86 9.3 0.3 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily HHH_8 PF14716.6 EHU01243.1 - 0.34 11.3 4.0 0.56 10.6 1.9 2.4 2 1 0 2 2 2 0 Helix-hairpin-helix domain Zn-ribbon_8 PF09723.10 EHU01243.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain TSNAXIP1_N PF15739.5 EHU01243.1 - 0.46 10.9 3.2 0.99 9.8 3.2 1.5 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus FAM184 PF15665.5 EHU01243.1 - 0.49 10.1 7.3 0.78 9.5 7.3 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B TMPIT PF07851.13 EHU01243.1 - 0.77 8.9 2.7 1.2 8.4 2.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein CREPT PF16566.5 EHU01243.1 - 2.3 8.4 8.3 1.1 9.5 5.2 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour HAUS-augmin3 PF14932.6 EHU01243.1 - 2.5 7.6 7.4 5.8 6.4 7.4 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 SlyX PF04102.12 EHU01243.1 - 8.5 7.1 8.7 17 6.1 2.1 3.0 1 1 1 2 2 2 0 SlyX YcaO PF02624.16 EHU01244.1 - 9.7e-82 274.8 0.0 2.5e-81 273.5 0.0 1.6 2 0 0 2 2 2 1 YcaO cyclodehydratase, ATP-ad Mg2+-binding YcaO_C PF18381.1 EHU01244.1 - 2.2e-66 223.0 0.0 3e-66 222.6 0.0 1.2 1 0 0 1 1 1 1 YcaO cyclodehydratase C-terminal domain SPOR PF05036.13 EHU01244.1 - 0.083 13.3 0.0 0.55 10.7 0.0 2.4 2 0 0 2 2 2 0 Sporulation related domain Aminotran_5 PF00266.19 EHU01245.1 - 1.1e-63 215.4 0.0 1.3e-63 215.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V EPSP_synthase PF00275.20 EHU01246.1 - 9.1e-155 515.4 0.0 1e-154 515.3 0.0 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Cytidylate_kin PF02224.18 EHU01247.1 - 9.9e-84 280.3 0.1 1.1e-83 280.1 0.1 1.0 1 0 0 1 1 1 1 Cytidylate kinase Cytidylate_kin2 PF13189.6 EHU01247.1 - 8.7e-09 35.7 0.1 1.6e-08 34.9 0.1 1.4 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_17 PF13207.6 EHU01247.1 - 1.5e-05 25.5 0.4 0.0026 18.2 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EHU01247.1 - 2.3e-05 24.9 0.1 0.00037 21.0 0.1 2.5 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EHU01247.1 - 0.0005 20.6 0.0 0.0011 19.5 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_33 PF13671.6 EHU01247.1 - 0.0016 18.6 0.2 0.0074 16.5 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EHU01247.1 - 0.0061 16.8 0.0 0.012 15.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 EHU01247.1 - 0.0072 16.5 0.1 0.29 11.2 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase ADK PF00406.22 EHU01247.1 - 0.012 15.8 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 Adenylate kinase dNK PF01712.19 EHU01247.1 - 0.022 14.6 0.0 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_30 PF13604.6 EHU01247.1 - 0.024 14.4 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EHU01247.1 - 0.029 14.4 0.0 0.054 13.5 0.0 1.5 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP_bind_2 PF03668.15 EHU01247.1 - 0.031 13.6 0.0 0.14 11.4 0.0 1.9 2 0 0 2 2 2 0 P-loop ATPase protein family PRK PF00485.18 EHU01247.1 - 0.14 11.9 0.0 0.36 10.5 0.0 1.7 2 1 1 3 3 3 0 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.20 EHU01247.1 - 0.14 12.0 0.2 2 8.3 0.0 2.5 3 0 0 3 3 3 0 Adenylylsulphate kinase AAA PF00004.29 EHU01247.1 - 0.15 12.5 0.0 0.38 11.2 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EHU01247.1 - 0.18 12.2 0.0 0.29 11.5 0.0 1.3 1 0 0 1 1 1 0 RNA helicase S1 PF00575.23 EHU01248.1 - 2.8e-101 332.0 32.1 4.4e-22 78.2 0.4 6.1 6 0 0 6 6 6 6 S1 RNA binding domain PCB_OB PF17092.5 EHU01248.1 - 1.3e-12 48.5 10.4 0.009 16.8 0.1 6.5 2 1 4 6 6 6 4 Penicillin-binding protein OB-like domain S1_2 PF13509.6 EHU01248.1 - 6.9e-05 22.8 8.9 7.3 6.7 0.2 6.4 5 3 0 5 5 5 3 S1 domain CsrA PF02599.16 EHU01248.1 - 0.0023 17.8 4.1 3.1 7.8 0.0 4.5 4 0 0 4 4 4 2 Global regulator protein family TOBE PF03459.17 EHU01248.1 - 0.076 13.3 3.1 11 6.4 0.1 3.5 3 0 0 3 3 3 0 TOBE domain DUF1344 PF07076.11 EHU01248.1 - 0.089 12.7 0.3 0.089 12.7 0.3 4.7 6 1 0 6 6 6 0 Protein of unknown function (DUF1344) CusF_Ec PF11604.8 EHU01248.1 - 1.7 8.6 5.6 11 6.1 0.1 4.7 4 2 0 4 4 4 0 Copper binding periplasmic protein CusF Bac_DNA_binding PF00216.21 EHU01249.1 - 1.8e-29 101.8 0.0 2e-29 101.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 EHU01249.1 - 4.4e-08 33.2 0.0 5.1e-08 33.1 0.0 1.0 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_bac_2 PF18175.1 EHU01249.1 - 0.00083 19.2 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 HU-CCDC81_euk_2 PF18289.1 EHU01249.1 - 0.034 14.3 0.0 0.051 13.7 0.0 1.2 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 HU-CCDC81_euk_1 PF14908.6 EHU01249.1 - 0.065 13.4 0.0 0.074 13.2 0.0 1.1 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 1 MDMPI_C PF07398.11 EHU01249.1 - 0.067 14.1 0.0 0.088 13.7 0.0 1.3 1 0 0 1 1 1 0 MDMPI C-terminal domain HU-DNA_bdg PF14848.6 EHU01249.1 - 0.17 11.9 0.0 0.31 11.1 0.0 1.5 1 1 0 1 1 1 0 DNA-binding domain Competence PF03772.16 EHU01250.1 - 1.9e-53 181.5 36.5 1.9e-53 181.5 36.5 2.0 2 0 0 2 2 2 1 Competence protein DUF4131 PF13567.6 EHU01250.1 - 4e-05 23.3 5.9 4e-05 23.3 5.9 5.0 3 3 1 4 4 4 1 Domain of unknown function (DUF4131) Lactamase_B PF00753.27 EHU01251.1 - 1.9e-11 44.4 0.2 2.1e-11 44.2 0.2 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EHU01251.1 - 0.00046 19.7 0.0 0.00059 19.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain ABC_membrane PF00664.23 EHU01253.1 - 1.2e-59 202.2 15.3 1.6e-59 201.8 15.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EHU01253.1 - 1.3e-35 122.9 0.2 4.7e-35 121.1 0.1 2.0 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EHU01253.1 - 3.7e-10 39.6 3.9 3.5e-09 36.4 3.9 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DEAD PF00270.29 EHU01253.1 - 1.4e-06 28.2 0.6 4.1e-06 26.7 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Zeta_toxin PF06414.12 EHU01253.1 - 0.00064 19.1 1.1 0.0017 17.6 0.0 2.1 3 0 0 3 3 3 1 Zeta toxin AAA_16 PF13191.6 EHU01253.1 - 0.00068 20.0 0.2 0.0015 18.9 0.2 1.5 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EHU01253.1 - 0.0011 18.9 0.0 0.0055 16.6 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 EHU01253.1 - 0.0011 18.6 0.3 0.0028 17.3 0.3 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EHU01253.1 - 0.0013 19.0 0.4 0.011 16.0 0.4 2.3 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 EHU01253.1 - 0.0014 18.4 0.0 0.003 17.3 0.0 1.5 1 0 0 1 1 1 1 Cytidylate kinase APS_kinase PF01583.20 EHU01253.1 - 0.0021 18.0 0.2 0.0053 16.7 0.0 1.8 2 0 0 2 2 1 1 Adenylylsulphate kinase DUF87 PF01935.17 EHU01253.1 - 0.0022 18.1 1.3 0.0076 16.4 0.2 2.3 2 1 0 2 2 2 1 Helicase HerA, central domain DUF2075 PF09848.9 EHU01253.1 - 0.0028 17.0 0.1 0.0044 16.3 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.6 EHU01253.1 - 0.0069 16.1 0.3 0.026 14.3 0.3 2.0 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EHU01253.1 - 0.012 15.4 0.7 2 8.1 0.1 2.2 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EHU01253.1 - 0.019 14.7 0.2 0.056 13.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EHU01253.1 - 0.019 14.7 0.1 0.051 13.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EHU01253.1 - 0.02 15.5 0.1 0.069 13.7 0.1 2.1 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EHU01253.1 - 0.042 13.9 0.1 0.095 12.8 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_15 PF13175.6 EHU01253.1 - 0.045 13.5 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EHU01253.1 - 0.046 14.1 0.5 1.9 8.9 0.5 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EHU01253.1 - 0.057 13.1 0.1 0.98 9.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 EHU01253.1 - 0.068 12.7 0.0 0.21 11.1 0.0 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region 6PF2K PF01591.18 EHU01253.1 - 0.091 12.1 0.1 0.27 10.5 0.0 1.7 2 0 0 2 2 2 0 6-phosphofructo-2-kinase SbcCD_C PF13558.6 EHU01253.1 - 0.12 12.7 1.2 3.9 7.8 0.2 3.2 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 EHU01253.1 - 0.12 12.3 0.0 0.46 10.5 0.0 2.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) LpxK PF02606.14 EHU01254.1 - 4.8e-118 394.0 0.1 5.6e-118 393.8 0.1 1.0 1 0 0 1 1 1 1 Tetraacyldisaccharide-1-P 4'-kinase MobB PF03205.14 EHU01254.1 - 0.00071 19.5 0.0 0.006 16.5 0.0 2.2 2 1 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_26 PF13500.6 EHU01254.1 - 0.0027 17.6 0.0 0.0051 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Glyco_transf_4 PF13439.6 EHU01254.1 - 0.0044 17.0 0.2 0.0084 16.1 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 CbiA PF01656.23 EHU01254.1 - 0.039 14.0 0.0 0.11 12.6 0.0 1.8 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 EHU01254.1 - 0.041 13.2 0.1 0.066 12.5 0.1 1.3 1 0 0 1 1 1 0 ATPase MipZ HTH_42 PF06224.12 EHU01255.1 - 9.6e-76 255.4 11.7 1.1e-75 255.2 11.7 1.1 1 0 0 1 1 1 1 Winged helix DNA-binding domain PCP_red PF08369.10 EHU01255.1 - 0.1 12.8 0.1 0.9 9.8 0.0 2.4 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit Trm112p PF03966.16 EHU01256.1 - 1.5e-09 38.3 0.2 2.7e-09 37.5 0.2 1.4 1 1 0 1 1 1 1 Trm112p-like protein A2L_zn_ribbon PF08792.10 EHU01256.1 - 0.0057 16.3 0.3 0.0069 16.1 0.3 1.2 1 0 0 1 1 1 1 A2L zinc ribbon domain TF_Zn_Ribbon PF08271.12 EHU01256.1 - 0.0061 16.0 0.2 0.011 15.2 0.2 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding PADR1 PF08063.12 EHU01256.1 - 0.022 14.5 0.2 0.027 14.2 0.2 1.2 1 0 0 1 1 1 0 PADR1 (NUC008) domain zf-C3HC4_5 PF17121.5 EHU01256.1 - 0.025 14.4 0.2 0.037 13.9 0.2 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2318 PF10080.9 EHU01256.1 - 0.057 13.5 0.0 0.064 13.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) CTP_transf_3 PF02348.19 EHU01257.1 - 4.2e-67 226.3 0.0 4.9e-67 226.1 0.0 1.0 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 EHU01257.1 - 4.9e-13 49.8 0.1 6e-13 49.5 0.1 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF2064 PF09837.9 EHU01257.1 - 0.002 18.0 0.8 0.0081 16.0 0.6 1.9 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2064) NTP_transferase PF00483.23 EHU01257.1 - 0.018 14.6 0.1 0.028 14.0 0.1 1.2 1 0 0 1 1 1 0 Nucleotidyl transferase DUF218 PF02698.17 EHU01258.1 - 1.3e-25 89.9 0.0 1.6e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 DUF218 domain Methyltransf_11 PF08241.12 EHU01259.1 - 1.2e-14 54.7 0.0 1.8e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EHU01259.1 - 1.2e-14 54.5 0.0 1.7e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EHU01259.1 - 6.5e-14 52.4 0.0 9.5e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EHU01259.1 - 1.8e-13 50.5 0.0 2.3e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EHU01259.1 - 4.9e-12 46.5 0.0 7.2e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EHU01259.1 - 1.1e-05 24.9 0.0 1.6e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EHU01259.1 - 0.00019 21.4 0.0 0.00022 21.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EHU01259.1 - 0.00025 20.6 0.0 0.00033 20.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 EHU01259.1 - 0.00083 18.7 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase UPF0020 PF01170.18 EHU01259.1 - 0.0093 15.7 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 DREV PF05219.12 EHU01259.1 - 0.015 14.4 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_15 PF09445.10 EHU01259.1 - 0.035 13.7 0.0 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase 3HCDH_N PF02737.18 EHU01259.1 - 0.17 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MukF_M PF17192.4 EHU01260.1 - 1.2e-83 278.7 4.2 2.6e-83 277.5 4.2 1.6 1 0 0 1 1 1 1 MukF middle domain MukF_C PF17193.4 EHU01260.1 - 5.1e-78 260.7 1.9 5.1e-78 260.7 1.9 1.8 2 0 0 2 2 2 1 MukF C-terminal domain KicB PF03882.14 EHU01260.1 - 8.9e-59 196.7 0.1 2.3e-58 195.4 0.1 1.8 1 0 0 1 1 1 1 MukF winged-helix domain PapD_C PF02753.17 EHU01260.1 - 0.094 13.1 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Pili assembly chaperone PapD, C-terminal domain CK2S PF15011.6 EHU01260.1 - 2.4 8.0 7.7 0.92 9.4 0.1 3.0 3 1 1 4 4 4 0 Casein Kinase 2 substrate MukE PF04288.13 EHU01261.1 - 5.3e-126 418.1 0.6 6.5e-126 417.9 0.6 1.0 1 0 0 1 1 1 1 MukE-like family DUF4194 PF13835.6 EHU01261.1 - 0.003 17.3 0.7 0.037 13.8 0.7 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4194) Tfb2 PF03849.14 EHU01261.1 - 0.034 13.1 0.0 0.042 12.8 0.0 1.1 1 0 0 1 1 1 0 Transcription factor Tfb2 DCD PF06559.11 EHU01261.1 - 0.079 11.7 0.0 0.15 10.8 0.0 1.4 2 0 0 2 2 2 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) MukB PF04310.12 EHU01262.1 - 2e-121 404.0 0.0 2e-121 404.0 0.0 3.1 3 0 0 3 3 3 1 MukB N-terminal MukB_hinge PF16330.5 EHU01262.1 - 1.4e-75 252.6 0.4 1.4e-75 252.6 0.4 3.8 5 0 0 5 5 5 1 MukB hinge domain SbcCD_C PF13558.6 EHU01262.1 - 5.4e-15 55.4 3.0 7.6e-15 54.9 0.0 2.9 4 0 0 4 4 3 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EHU01262.1 - 4.3e-08 32.8 0.2 8.6e-08 31.8 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EHU01262.1 - 7.2e-05 23.4 0.1 7.2e-05 23.4 0.1 7.6 4 2 0 4 4 2 1 AAA domain DUF4238 PF14022.6 EHU01262.1 - 0.0018 17.9 2.2 0.0018 17.9 2.2 3.0 3 1 0 3 3 3 1 Protein of unknown function (DUF4238) SMC_N PF02463.19 EHU01262.1 - 0.022 14.2 2.2 4.1 6.8 0.0 3.1 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain Nsp1_C PF05064.13 EHU01262.1 - 0.028 14.2 0.4 0.028 14.2 0.4 7.7 8 1 0 9 9 8 0 Nsp1-like C-terminal region DUF3713 PF12506.8 EHU01262.1 - 0.067 13.5 0.2 0.51 10.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) ABC_tran PF00005.27 EHU01262.1 - 0.31 11.5 0.0 0.31 11.5 0.0 6.7 6 2 0 6 6 5 0 ABC transporter AAA_15 PF13175.6 EHU01262.1 - 3.1 7.4 11.0 0.36 10.5 0.0 3.3 3 1 0 3 3 3 0 AAA ATPase domain HlyD_2 PF12700.7 EHU01262.1 - 4.5 5.9 7.6 0.59 8.8 0.4 2.4 2 0 0 2 2 2 0 HlyD family secretion protein YkuD PF03734.14 EHU01263.1 - 2.9e-29 102.4 0.0 4.9e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain PG_binding_1 PF01471.18 EHU01263.1 - 3.1e-08 33.7 2.4 3.4e-07 30.4 0.1 3.0 3 0 0 3 3 3 1 Putative peptidoglycan binding domain PG_binding_3 PF09374.10 EHU01263.1 - 0.035 14.3 0.1 0.078 13.3 0.1 1.6 1 0 0 1 1 1 0 Predicted Peptidoglycan domain Peptidase_M15_2 PF05951.13 EHU01264.1 - 7.1e-61 204.4 0.0 8.4e-61 204.1 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF882) Peptidase_M15_3 PF08291.11 EHU01264.1 - 6.1e-12 45.6 0.0 7.9e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase M15 Lactamase_B PF00753.27 EHU01265.1 - 5.9e-28 98.2 1.8 6.8e-28 98.0 1.8 1.0 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EHU01265.1 - 0.0002 20.9 0.1 0.00028 20.5 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Aminotran_1_2 PF00155.21 EHU01266.1 - 6.6e-90 301.9 0.0 7.5e-90 301.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Porin_1 PF00267.21 EHU01267.1 - 8.9e-134 446.2 26.9 1.1e-133 445.9 26.9 1.1 1 0 0 1 1 1 1 Gram-negative porin Porin_4 PF13609.6 EHU01267.1 - 9.7e-15 55.1 48.8 3.2e-11 43.5 49.4 2.0 1 1 1 2 2 2 2 Gram-negative porin tRNA-synt_2 PF00152.20 EHU01268.1 - 3e-82 276.2 0.0 3.7e-82 275.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EHU01268.1 - 1.5e-12 47.3 0.5 5.2e-12 45.6 0.2 2.0 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EHU01268.1 - 0.031 13.8 0.1 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) tRNA-synt_His PF13393.6 EHU01268.1 - 0.14 11.4 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Histidyl-tRNA synthetase NAPRTase PF04095.16 EHU01269.1 - 9.8e-80 267.6 0.0 1.3e-79 267.3 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 EHU01269.1 - 1.2e-35 122.7 0.1 2.4e-35 121.7 0.1 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain DUF3458_C PF17432.2 EHU01270.1 - 5.4e-119 397.3 11.1 8e-119 396.7 11.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1 PF01433.20 EHU01270.1 - 3.4e-55 187.0 0.9 6.3e-55 186.1 0.9 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain DUF3458 PF11940.8 EHU01270.1 - 2.1e-33 114.6 0.4 6.3e-33 113.1 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3458) Ig-like fold Peptidase_M1_N PF17900.1 EHU01270.1 - 1.3e-14 54.8 0.0 2.4e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Ovate PF04844.13 EHU01270.1 - 0.0024 17.8 0.1 0.013 15.5 0.0 2.2 2 0 0 2 2 2 1 Transcriptional repressor, ovate DUF2063 PF09836.9 EHU01270.1 - 0.075 13.3 0.3 2.6 8.4 0.0 3.2 3 0 0 3 3 3 0 Putative DNA-binding domain ABC_tran PF00005.27 EHU01271.1 - 1.1e-30 107.0 0.0 1.6e-30 106.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EHU01271.1 - 1.2e-06 28.6 0.1 0.012 15.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EHU01271.1 - 3.4e-06 27.5 1.6 5.3e-06 26.9 1.6 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EHU01271.1 - 7.5e-06 26.3 0.1 2.3e-05 24.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 EHU01271.1 - 2.4e-05 23.9 0.0 0.03 13.7 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 EHU01271.1 - 0.00025 21.3 0.2 0.079 13.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EHU01271.1 - 0.00047 20.1 0.0 0.00083 19.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_33 PF13671.6 EHU01271.1 - 0.00047 20.3 0.0 0.0015 18.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EHU01271.1 - 0.0016 18.2 0.4 0.0063 16.3 0.2 2.0 1 1 1 2 2 2 1 AAA domain AAA_25 PF13481.6 EHU01271.1 - 0.002 17.8 0.6 0.016 14.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EHU01271.1 - 0.0026 17.8 0.1 0.0034 17.4 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATPase PF06745.13 EHU01271.1 - 0.0046 16.3 0.0 0.79 9.0 0.0 2.1 2 0 0 2 2 2 1 KaiC ABC_ATPase PF09818.9 EHU01271.1 - 0.0084 14.9 0.3 2 7.1 0.0 2.6 2 1 0 2 2 2 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 EHU01271.1 - 0.013 15.3 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 EHU01271.1 - 0.014 14.6 0.1 0.042 13.0 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.12 EHU01271.1 - 0.017 15.0 0.5 0.093 12.6 0.1 2.1 2 0 0 2 2 2 0 NACHT domain DLIC PF05783.11 EHU01271.1 - 0.034 13.0 0.0 0.048 12.5 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Dynamin_N PF00350.23 EHU01271.1 - 0.049 13.7 0.1 0.26 11.4 0.1 2.0 1 1 0 1 1 1 0 Dynamin family AAA_18 PF13238.6 EHU01271.1 - 0.15 12.6 0.0 0.27 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EHU01271.1 - 0.19 11.7 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_23 PF13476.6 EHU01271.1 - 0.21 12.1 0.0 0.33 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain Bac_luciferase PF00296.20 EHU01272.1 - 2.7e-87 293.1 9.8 3.5e-87 292.8 9.8 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase NMT1 PF09084.11 EHU01273.1 - 1.1e-13 51.6 0.0 1.6e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.20 EHU01273.1 - 8.2e-13 48.3 0.0 1.9e-09 37.3 0.0 2.3 1 1 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 NMT1_2 PF13379.6 EHU01273.1 - 5.8e-12 45.9 0.0 1.9e-11 44.1 0.0 1.8 1 1 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 EHU01273.1 - 2.7e-10 40.2 0.1 7.3e-10 38.8 0.1 1.7 1 1 1 2 2 2 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_3 PF16868.5 EHU01273.1 - 2e-08 34.0 0.0 7e-08 32.2 0.0 1.8 2 0 0 2 2 2 1 NMT1-like family OpuAC PF04069.12 EHU01273.1 - 3.4e-07 30.1 0.0 4.7e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system LysR_substrate PF03466.20 EHU01273.1 - 0.017 14.5 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 LysR substrate binding domain HEM4 PF02602.15 EHU01273.1 - 0.05 12.9 0.0 0.094 12.1 0.0 1.4 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD FMN_red PF03358.15 EHU01274.1 - 1.6e-31 109.1 0.0 1.9e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EHU01274.1 - 2.8e-08 33.7 0.0 3.5e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Glycos_transf_2 PF00535.26 EHU01275.1 - 1.9e-31 109.2 0.0 3.2e-31 108.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EHU01275.1 - 4.9e-13 49.5 0.0 7.2e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EHU01275.1 - 3.3e-09 36.6 0.2 1e-08 35.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DUF3932 PF13068.6 EHU01275.1 - 0.0014 18.9 0.1 0.067 13.5 0.0 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF3932) Glyco_tranf_2_4 PF13704.6 EHU01275.1 - 0.002 18.6 0.0 0.0054 17.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 2 DUF373 PF04123.13 EHU01275.1 - 0.18 11.2 0.3 0.29 10.5 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Polysacc_synt PF01943.17 EHU01276.1 - 1.1e-34 120.1 22.1 4.5e-33 114.8 10.7 2.0 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein Polysacc_synt_3 PF13440.6 EHU01276.1 - 1.8e-11 43.8 8.7 1.8e-11 43.8 8.7 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein MatE PF01554.18 EHU01276.1 - 1.9e-07 30.9 5.0 1.9e-07 30.9 5.0 3.5 3 2 1 4 4 4 1 MatE Polysacc_synt_C PF14667.6 EHU01276.1 - 5.5e-07 29.7 7.5 5.5e-07 29.7 7.5 4.4 2 2 3 5 5 5 1 Polysaccharide biosynthesis C-terminal domain DHO_dh PF01180.21 EHU01277.1 - 6.8e-90 301.2 0.1 8.4e-90 300.9 0.1 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Peripla_BP_4 PF13407.6 EHU01277.1 - 0.17 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein domain ZapC PF07126.12 EHU01278.1 - 1.4e-71 239.5 0.0 1.6e-71 239.3 0.0 1.0 1 0 0 1 1 1 1 Cell-division protein ZapC MOSC_N PF03476.16 EHU01279.1 - 2.9e-28 98.1 0.0 5.2e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 EHU01279.1 - 3.3e-28 98.3 0.0 5.4e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 MOSC domain Fer2 PF00111.27 EHU01279.1 - 4.1e-13 49.1 1.0 7e-13 48.3 0.2 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 EHU01279.1 - 0.052 13.6 0.1 0.13 12.3 0.1 1.7 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain UPF0020 PF01170.18 EHU01280.1 - 1.8e-64 217.1 0.0 9.6e-61 204.9 0.0 2.4 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Methyltrans_SAM PF10672.9 EHU01280.1 - 1.1e-23 83.9 0.1 2.2e-23 82.9 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase THUMP PF02926.17 EHU01280.1 - 1.1e-14 54.7 0.0 1.8e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 THUMP domain Cons_hypoth95 PF03602.15 EHU01280.1 - 1e-13 51.3 0.0 9.1e-10 38.5 0.0 3.5 3 0 0 3 3 3 2 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 EHU01280.1 - 1.4e-10 41.2 0.0 5.8e-05 22.9 0.0 3.4 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.6 EHU01280.1 - 3.3e-09 37.3 0.0 5.4e-05 23.8 0.0 3.7 4 0 0 4 4 4 2 Methyltransferase domain Methyltransf_11 PF08241.12 EHU01280.1 - 8.3e-09 36.0 0.0 5.9e-05 23.6 0.0 3.0 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_15 PF09445.10 EHU01280.1 - 0.0022 17.6 0.0 0.031 13.8 0.0 2.4 3 0 0 3 3 3 1 RNA cap guanine-N2 methyltransferase N6_Mtase PF02384.16 EHU01280.1 - 0.16 11.2 0.5 6.1 6.0 0.0 3.0 3 1 0 3 3 3 0 N-6 DNA Methylase ABC_tran PF00005.27 EHU01281.1 - 2.9e-50 170.3 0.2 1.6e-23 83.7 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_tran_CTD PF16326.5 EHU01281.1 - 4.2e-24 84.6 3.2 2.4e-23 82.2 3.2 2.4 1 0 0 1 1 1 1 ABC transporter C-terminal domain AAA_21 PF13304.6 EHU01281.1 - 1.8e-19 70.7 4.0 0.00083 19.2 0.3 4.6 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EHU01281.1 - 3.3e-11 43.0 0.1 0.00036 20.1 0.0 4.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_tran_Xtn PF12848.7 EHU01281.1 - 1.9e-10 40.6 1.5 1.9e-10 40.6 1.5 2.7 2 0 0 2 2 2 1 ABC transporter AAA_15 PF13175.6 EHU01281.1 - 2.1e-09 37.6 0.1 0.0017 18.1 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 EHU01281.1 - 2.5e-09 37.5 3.0 0.00012 22.4 0.1 4.1 3 2 0 3 3 2 2 AAA domain AAA_16 PF13191.6 EHU01281.1 - 3.1e-09 37.4 4.1 5.6e-07 30.1 0.1 3.4 3 1 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 EHU01281.1 - 7.3e-08 32.0 0.0 0.0057 16.4 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EHU01281.1 - 2e-07 31.7 8.2 0.054 14.0 0.0 3.8 4 0 0 4 4 3 2 AAA domain TsaE PF02367.17 EHU01281.1 - 2.6e-07 30.7 0.0 0.0003 20.8 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 EHU01281.1 - 5.8e-07 29.6 0.0 0.039 13.9 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_13 PF13166.6 EHU01281.1 - 1.4e-06 27.3 0.7 0.15 10.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 EHU01281.1 - 2.2e-06 27.7 0.3 0.012 15.5 0.4 2.9 2 1 0 2 2 2 2 NACHT domain AAA_30 PF13604.6 EHU01281.1 - 5.6e-06 26.2 0.1 0.17 11.6 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA PF00004.29 EHU01281.1 - 6.3e-06 26.7 0.0 0.0066 16.9 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EHU01281.1 - 1.3e-05 25.0 0.0 0.3 10.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 EHU01281.1 - 1.4e-05 25.3 0.9 0.019 15.1 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_7 PF12775.7 EHU01281.1 - 1.8e-05 24.3 0.0 0.12 11.9 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region MMR_HSR1 PF01926.23 EHU01281.1 - 1.8e-05 24.7 0.0 0.15 12.2 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase ATPase_2 PF01637.18 EHU01281.1 - 2.9e-05 24.1 0.2 0.04 13.8 0.0 3.1 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 EHU01281.1 - 4.5e-05 23.8 0.0 0.13 12.6 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_28 PF13521.6 EHU01281.1 - 8.2e-05 22.9 0.0 0.049 13.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 EHU01281.1 - 8.2e-05 22.4 0.1 0.31 10.8 0.1 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 EHU01281.1 - 0.00011 22.3 0.4 0.2 11.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 EHU01281.1 - 0.00014 21.2 0.4 2.2 7.5 0.0 3.4 2 1 1 3 3 3 2 Zeta toxin NB-ARC PF00931.22 EHU01281.1 - 0.00015 21.1 0.0 0.43 9.7 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_18 PF13238.6 EHU01281.1 - 0.00015 22.3 0.1 0.2 12.2 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EHU01281.1 - 0.00022 20.9 0.0 1.2 8.7 0.0 3.5 3 0 0 3 3 3 1 AAA domain Roc PF08477.13 EHU01281.1 - 0.00029 21.0 0.0 0.63 10.3 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 EHU01281.1 - 0.00029 20.9 0.0 0.064 13.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EHU01281.1 - 0.00041 20.1 0.0 1.2 8.8 0.0 2.9 3 0 0 3 3 2 2 IstB-like ATP binding protein DUF87 PF01935.17 EHU01281.1 - 0.00043 20.4 1.7 13 5.8 0.0 3.7 4 0 0 4 4 3 0 Helicase HerA, central domain ATP-synt_ab PF00006.25 EHU01281.1 - 0.00078 19.2 0.0 0.13 11.9 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.13 EHU01281.1 - 0.00083 18.6 0.0 0.68 9.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) MobB PF03205.14 EHU01281.1 - 0.0013 18.6 0.1 0.055 13.4 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B T2SSE PF00437.20 EHU01281.1 - 0.0017 17.5 0.0 0.029 13.4 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein RuvB_N PF05496.12 EHU01281.1 - 0.0029 17.4 0.0 0.4 10.4 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 EHU01281.1 - 0.0036 17.2 1.7 0.46 10.4 0.0 3.1 3 0 0 3 3 3 1 NTPase cobW PF02492.19 EHU01281.1 - 0.0061 16.2 0.0 1 8.9 0.0 3.1 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.20 EHU01281.1 - 0.0093 15.2 0.3 2.3 7.3 0.0 2.8 3 0 0 3 3 3 1 G-protein alpha subunit Dynamin_N PF00350.23 EHU01281.1 - 0.0097 16.0 0.3 0.2 11.7 0.0 2.9 3 1 0 3 3 3 1 Dynamin family Rad17 PF03215.15 EHU01281.1 - 0.011 15.6 0.0 0.26 11.2 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain TrwB_AAD_bind PF10412.9 EHU01281.1 - 0.012 14.5 1.4 0.93 8.3 0.1 3.1 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain AAA_19 PF13245.6 EHU01281.1 - 0.021 15.2 0.4 0.21 11.9 0.3 2.6 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.22 EHU01281.1 - 0.029 14.0 0.4 1.3 8.6 0.1 2.8 2 1 1 3 3 3 0 SRP54-type protein, GTPase domain AAA_17 PF13207.6 EHU01281.1 - 0.031 14.7 1.5 2.7 8.4 0.0 3.8 3 1 0 3 3 2 0 AAA domain DLIC PF05783.11 EHU01281.1 - 0.044 12.6 1.9 2.4 6.9 0.0 2.7 3 0 0 3 3 3 0 Dynein light intermediate chain (DLIC) MeaB PF03308.16 EHU01281.1 - 0.046 12.7 0.0 9.3 5.1 0.0 2.5 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DAP3 PF10236.9 EHU01281.1 - 0.055 12.6 0.1 13 4.8 0.0 2.9 3 0 0 3 3 2 0 Mitochondrial ribosomal death-associated protein 3 Fmp27_WPPW PF10359.9 EHU01281.1 - 0.063 12.1 1.2 0.1 11.4 1.2 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Arf PF00025.21 EHU01281.1 - 0.098 12.1 0.1 18 4.7 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family Mg_chelatase PF01078.21 EHU01281.1 - 0.11 11.9 0.0 5.7 6.3 0.0 2.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Gtr1_RagA PF04670.12 EHU01281.1 - 0.12 11.8 0.0 2.6 7.4 0.0 2.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_11 PF13086.6 EHU01281.1 - 0.12 12.2 7.1 1.3 8.8 0.0 2.7 3 0 0 3 3 2 0 AAA domain FeoB_N PF02421.18 EHU01281.1 - 0.17 11.4 0.1 20 4.7 0.0 2.6 3 0 0 3 3 2 0 Ferrous iron transport protein B Laminin_II PF06009.12 EHU01281.1 - 0.39 10.7 6.4 0.18 11.8 2.6 2.3 3 0 0 3 3 2 0 Laminin Domain II WDCP PF15390.6 EHU01281.1 - 0.4 9.0 2.0 0.62 8.4 2.0 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Prefoldin_2 PF01920.20 EHU01281.1 - 2.7 8.0 10.3 2.4e+02 1.7 8.6 3.4 2 1 0 2 2 2 0 Prefoldin subunit DUF3584 PF12128.8 EHU01281.1 - 4.6 4.6 24.4 1.5 6.3 6.3 3.6 5 0 0 5 5 4 0 Protein of unknown function (DUF3584) DivIC PF04977.15 EHU01281.1 - 9.9 6.0 9.2 21 5.0 0.4 3.3 3 0 0 3 3 3 0 Septum formation initiator PqiA PF04403.13 EHU01282.1 - 1.2e-90 301.3 35.7 1e-53 181.3 14.1 2.1 2 0 0 2 2 2 2 Paraquat-inducible protein A UPF0547 PF10571.9 EHU01282.1 - 0.0004 20.4 16.0 0.0096 16.0 9.0 3.3 3 0 0 3 3 3 1 Uncharacterised protein family UPF0547 DZR PF12773.7 EHU01282.1 - 0.0034 17.4 10.7 0.095 12.7 0.8 2.4 2 0 0 2 2 2 2 Double zinc ribbon Tmemb_55A PF09788.9 EHU01282.1 - 0.38 9.8 0.0 0.38 9.8 0.0 2.9 2 1 1 3 3 3 0 Transmembrane protein 55A Mu-like_Com PF10122.9 EHU01282.1 - 0.98 8.9 5.5 1.6 8.3 1.4 2.6 2 0 0 2 2 2 0 Mu-like prophage protein Com Zn_Tnp_IS91 PF14319.6 EHU01282.1 - 1.1 9.3 4.6 1.7 8.7 0.1 2.3 2 0 0 2 2 2 0 Transposase zinc-binding domain TackOD1 PF18551.1 EHU01282.1 - 4.9 6.8 6.1 24 4.6 1.2 2.3 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 MlaD PF02470.20 EHU01283.1 - 5.7e-36 122.7 0.3 1.6e-13 50.8 0.0 3.5 3 0 0 3 3 3 3 MlaD protein DUF948 PF06103.11 EHU01283.1 - 0.0026 18.0 1.5 0.026 14.8 0.7 2.3 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF948) EzrA PF06160.12 EHU01283.1 - 0.22 9.6 0.5 0.42 8.7 0.5 1.4 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA ABC_trans_aux PF03886.13 EHU01284.1 - 1.1e-37 129.2 4.8 1.2e-37 128.9 4.8 1.0 1 0 0 1 1 1 1 ABC-type transport auxiliary lipoprotein component RMF PF04957.12 EHU01285.1 - 1.9e-30 104.8 5.6 2.1e-30 104.7 5.6 1.0 1 0 0 1 1 1 1 Ribosome modulation factor FabA PF07977.13 EHU01286.1 - 5.7e-54 181.5 0.0 6.7e-54 181.3 0.0 1.1 1 0 0 1 1 1 1 FabA-like domain AAA_32 PF13654.6 EHU01287.1 - 9.5e-18 64.3 0.0 1.5e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Lon_C PF05362.13 EHU01287.1 - 7.7e-09 35.4 0.0 1.9e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain MatP PF06303.12 EHU01288.1 - 5.2e-43 145.5 2.8 5.2e-43 145.5 2.8 1.7 2 0 0 2 2 2 1 MatP N-terminal domain MatP_C PF17414.2 EHU01288.1 - 4.9e-32 109.9 1.6 8.2e-32 109.2 1.6 1.4 1 0 0 1 1 1 1 MatP C-terminal ribbon-helix-helix domain RHH_4 PF13467.6 EHU01288.1 - 0.00012 21.9 0.1 0.00021 21.1 0.1 1.4 1 0 0 1 1 1 1 Ribbon-helix-helix domain TMF_TATA_bd PF12325.8 EHU01288.1 - 0.026 14.7 0.7 0.026 14.7 0.7 1.8 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding PRP1_N PF06424.12 EHU01288.1 - 0.18 12.2 4.1 0.8 10.1 0.3 2.1 1 1 1 2 2 2 0 PRP1 splicing factor, N-terminal OmpA_membrane PF01389.17 EHU01289.1 - 9.1e-73 243.9 3.4 1.2e-72 243.5 3.4 1.1 1 0 0 1 1 1 1 OmpA-like transmembrane domain OmpA PF00691.20 EHU01289.1 - 2.2e-24 85.7 0.0 3.7e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 OmpA family OMP_b-brl PF13505.6 EHU01289.1 - 2.5e-21 76.6 11.8 3.4e-21 76.2 11.8 1.1 1 0 0 1 1 1 1 Outer membrane protein beta-barrel domain DUF2490 PF10677.9 EHU01289.1 - 0.0039 17.2 0.3 0.62 10.0 0.3 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2490) Opacity PF02462.15 EHU01289.1 - 0.01 15.9 0.4 0.26 11.4 0.0 2.3 1 1 0 2 2 2 0 Opacity family porin protein Pilus_CpaD PF09476.10 EHU01289.1 - 0.041 13.6 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) SulA PF03846.14 EHU01290.1 - 1e-47 160.8 2.5 1.2e-47 160.5 2.5 1.1 1 0 0 1 1 1 1 Cell division inhibitor SulA TfoX_N PF04993.13 EHU01291.1 - 1.1e-26 92.9 0.0 1.6e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 TfoX N-terminal domain TfoX_C PF04994.13 EHU01291.1 - 1.4e-21 76.4 0.0 2.6e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 TfoX C-terminal domain Cdd1 PF11731.8 EHU01291.1 - 0.046 14.0 0.0 0.079 13.2 0.0 1.4 1 0 0 1 1 1 0 Pathogenicity locus FUSC-like PF12805.7 EHU01292.1 - 2.9e-99 331.8 8.3 2.9e-99 331.8 8.3 2.2 2 0 0 2 2 2 1 FUSC-like inner membrane protein yccS FUSC_2 PF13515.6 EHU01292.1 - 1.7e-23 83.1 11.9 1.7e-23 83.1 11.9 3.0 2 1 1 3 3 3 1 Fusaric acid resistance protein-like FUSC PF04632.12 EHU01292.1 - 3.4e-09 35.8 34.3 3.2e-07 29.3 11.0 3.1 1 1 2 3 3 3 2 Fusaric acid resistance protein family ALMT PF11744.8 EHU01292.1 - 0.035 12.9 3.1 0.03 13.2 0.6 2.1 2 1 0 2 2 2 0 Aluminium activated malate transporter YccF PF03733.13 EHU01293.1 - 2.1e-27 95.6 29.0 2.8e-17 63.1 14.1 2.1 2 0 0 2 2 2 2 Inner membrane component domain DUF5362 PF17319.2 EHU01293.1 - 2 8.3 7.9 0.38 10.6 3.6 2.0 2 1 0 2 2 2 0 Family of unknown function (DUF5362) Helicase_IV_N PF12462.8 EHU01294.1 - 9.1e-65 217.5 4.3 9.1e-65 217.5 4.3 2.4 4 0 0 4 4 4 1 DNA helicase IV / RNA helicase N terminal UvrD-helicase PF00580.21 EHU01294.1 - 6.5e-39 134.3 0.0 9.8e-38 130.4 0.0 2.3 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 EHU01294.1 - 8.3e-31 107.3 0.0 1.7e-30 106.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C PF13361.6 EHU01294.1 - 4.1e-14 52.7 0.0 7.1e-13 48.6 0.0 2.2 1 1 1 2 2 2 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 EHU01294.1 - 1.3e-10 41.0 0.1 8.4e-05 22.3 0.0 2.7 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 EHU01294.1 - 2.8e-08 33.7 0.2 5.2e-05 23.1 0.1 2.3 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 EHU01294.1 - 0.0011 18.7 0.1 0.3 10.8 0.0 3.4 3 1 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 EHU01294.1 - 0.0012 18.5 0.0 0.029 14.0 0.0 2.6 2 1 0 3 3 3 1 AAA domain STAT_int PF02865.17 EHU01294.1 - 0.0012 19.3 1.0 0.004 17.6 1.0 1.9 1 0 0 1 1 1 1 STAT protein, protein interaction domain DUF1351 PF07083.11 EHU01294.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) DEAD PF00270.29 EHU01294.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_16 PF13191.6 EHU01294.1 - 1.7 9.0 9.5 8.9 6.7 6.5 3.2 2 1 0 2 2 2 0 AAA ATPase domain MGS PF02142.22 EHU01295.1 - 3.1e-17 62.5 0.0 4.4e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 MGS-like domain DUF2057 PF09829.9 EHU01296.1 - 1.8e-33 116.4 0.0 2e-33 116.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2057) CoA_binding_2 PF13380.6 EHU01297.1 - 9.6e-38 129.2 0.0 1.1e-37 129.1 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 EHU01297.1 - 5.5e-07 30.2 0.0 8.7e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 CoA binding domain YccV-like PF08755.11 EHU01298.1 - 3.8e-20 72.2 0.0 4.3e-20 72.0 0.0 1.0 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Methyltrans_SAM PF10672.9 EHU01299.1 - 1.9e-28 99.5 0.0 2.7e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase PUA_3 PF17785.1 EHU01299.1 - 4.1e-21 74.5 0.1 1e-20 73.3 0.1 1.7 1 0 0 1 1 1 1 PUA-like domain Methyltransf_31 PF13847.6 EHU01299.1 - 3.6e-11 43.1 0.1 5.6e-11 42.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EHU01299.1 - 1.7e-10 40.8 0.0 2.7e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 EHU01299.1 - 1e-05 25.1 0.0 1.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EHU01299.1 - 1.5e-05 25.6 0.0 9.5e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.10 EHU01299.1 - 0.00072 19.2 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase TRM PF02005.16 EHU01299.1 - 0.0015 17.8 0.0 0.002 17.4 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_11 PF08241.12 EHU01299.1 - 0.002 18.7 0.1 0.068 13.8 0.0 2.6 3 0 0 3 3 2 1 Methyltransferase domain PrmA PF06325.13 EHU01299.1 - 0.0032 16.9 0.0 0.0046 16.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PUA PF01472.20 EHU01299.1 - 0.0064 16.4 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 PUA domain Met_10 PF02475.16 EHU01299.1 - 0.034 13.9 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_10 PF05971.12 EHU01299.1 - 0.042 13.2 0.0 0.061 12.7 0.0 1.2 1 0 0 1 1 1 0 RNA methyltransferase Methyltransf_12 PF08242.12 EHU01299.1 - 0.065 14.0 0.1 0.35 11.6 0.0 2.2 3 0 0 3 3 2 0 Methyltransferase domain Acylphosphatase PF00708.18 EHU01300.1 - 2.5e-24 85.5 0.0 2.7e-24 85.4 0.0 1.0 1 0 0 1 1 1 1 Acylphosphatase DsrC PF04358.13 EHU01301.1 - 3.1e-45 153.1 0.0 3.4e-45 153.0 0.0 1.0 1 0 0 1 1 1 1 DsrC like protein Acyltransferase PF01553.21 EHU01301.1 - 0.053 13.1 0.0 0.069 12.8 0.0 1.1 1 0 0 1 1 1 0 Acyltransferase Bax1-I PF01027.20 EHU01302.1 - 3.4e-41 141.4 33.5 3.9e-41 141.2 33.5 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 His_Phos_2 PF00328.22 EHU01303.1 - 3.5e-19 69.4 6.9 4.8e-09 36.1 0.0 3.1 2 1 0 3 3 3 2 Histidine phosphatase superfamily (branch 2) VIR_N PF15912.5 EHU01303.1 - 0.21 11.1 5.5 0.35 10.4 5.5 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal HC2 PF07382.11 EHU01303.1 - 0.28 11.3 45.2 0.025 14.7 39.9 1.8 2 0 0 2 2 2 0 Histone H1-like nucleoprotein HC2 Aldedh PF00171.22 EHU01304.1 - 4.9e-132 440.7 0.0 5.5e-132 440.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family baeRF_family2 PF18844.1 EHU01304.1 - 0.00044 20.3 0.7 0.0014 18.7 0.7 1.8 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 2 Peptidase_S78_2 PF14550.6 EHU01304.1 - 0.15 12.2 0.0 0.39 10.8 0.0 1.7 1 0 0 1 1 1 0 Putative phage serine protease XkdF YccJ PF13993.6 EHU01305.1 - 7.6e-38 128.7 2.8 8.5e-38 128.5 2.8 1.0 1 0 0 1 1 1 1 YccJ-like protein FMN_red PF03358.15 EHU01306.1 - 1.8e-13 50.5 0.0 2.3e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 EHU01306.1 - 4.8e-07 30.1 0.0 6.3e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 EHU01306.1 - 1.4e-06 28.6 0.0 0.012 15.8 0.0 2.2 1 1 1 2 2 2 2 Flavodoxin domain Flavodoxin_2 PF02525.17 EHU01306.1 - 5.9e-05 22.9 0.0 7.6e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold EamA PF00892.20 EHU01307.1 - 7.5e-05 22.9 4.0 8.4e-05 22.8 4.0 1.2 1 0 0 1 1 1 1 EamA-like transporter family EamA PF00892.20 EHU01308.1 - 8.9e-18 64.8 15.0 4.3e-12 46.4 5.2 2.0 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EHU01308.1 - 8.2e-06 25.4 0.4 1.4e-05 24.6 0.4 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family DUF2070 PF09843.9 EHU01308.1 - 0.0076 14.6 1.9 0.0093 14.3 1.9 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) TetR_C_3 PF08362.11 EHU01309.1 - 2.8e-35 121.3 0.1 3.8e-35 120.9 0.1 1.1 1 0 0 1 1 1 1 YcdC-like protein, C-terminal region TetR_N PF00440.23 EHU01309.1 - 7.4e-14 51.3 0.0 1.3e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family Arm-DNA-bind_2 PF12167.8 EHU01310.1 - 4.1e-22 77.9 0.0 1.1e-21 76.6 0.0 1.8 1 0 0 1 1 1 1 Arm DNA-binding domain Phage_integrase PF00589.22 EHU01310.1 - 1.6e-20 73.6 0.0 3.3e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_3 PF14659.6 EHU01310.1 - 0.12 12.7 0.0 0.33 11.2 0.0 1.8 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 EHU01310.1 - 0.18 12.2 0.1 0.99 9.8 0.0 2.2 3 0 0 3 3 3 0 Phage integrase SAM-like domain LexA_DNA_bind PF01726.16 EHU01311.1 - 7.8e-17 60.8 0.0 1.2e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 LexA DNA binding domain NPCBM_assoc PF10633.9 EHU01312.1 - 0.077 13.3 0.6 0.21 11.9 0.5 1.8 1 1 1 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase KilA-N PF04383.13 EHU01317.1 - 1.6e-15 56.9 0.0 3.1e-15 56.0 0.0 1.4 2 0 0 2 2 2 1 KilA-N domain BssS PF13991.6 EHU01317.1 - 0.14 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 BssS protein family UNC119_bdg PF15435.6 EHU01321.1 - 0.077 12.5 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 UNC119-binding protein C5orf30 homologue RlmM_FDX PF18125.1 EHU01322.1 - 0.15 12.6 0.3 0.46 11.0 0.1 1.8 2 1 1 3 3 3 0 RlmM ferredoxin-like domain DUF2153 PF09921.9 EHU01323.1 - 0.031 14.1 0.2 0.042 13.7 0.1 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) ResIII PF04851.15 EHU01328.1 - 1.7e-12 47.7 0.0 4.4e-12 46.3 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EHU01328.1 - 2.2e-07 31.2 0.0 5.2e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EHU01328.1 - 0.00011 22.0 0.0 0.00082 19.2 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 EHU01328.1 - 0.0017 18.1 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain MmcB-like PF06319.12 EHU01328.1 - 0.0092 15.7 0.4 0.079 12.6 0.1 2.4 2 1 1 3 3 3 1 DNA repair protein MmcB-like IstB_IS21 PF01695.17 EHU01328.1 - 0.025 14.3 0.0 0.089 12.5 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_22 PF13401.6 EHU01328.1 - 0.032 14.5 0.0 0.14 12.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 EHU01328.1 - 0.058 13.2 0.0 0.19 11.6 0.0 1.8 2 0 0 2 2 2 0 Helicase DZR PF12773.7 EHU01328.1 - 0.074 13.1 1.0 0.15 12.1 1.0 1.4 1 0 0 1 1 1 0 Double zinc ribbon DUF5596 PF18082.1 EHU01328.1 - 0.088 12.6 0.0 0.37 10.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5596) zf-HIT PF04438.16 EHU01328.1 - 1.2 9.1 4.0 2 8.4 4.0 1.3 1 0 0 1 1 1 0 HIT zinc finger Prim_Zn_Ribbon PF08273.12 EHU01329.1 - 2.3e-11 43.8 8.7 4.1e-11 43.0 8.7 1.4 1 0 0 1 1 1 1 Zinc-binding domain of primase-helicase Toprim_3 PF13362.6 EHU01329.1 - 4.4e-11 43.0 0.0 1e-10 41.8 0.0 1.7 1 0 0 1 1 1 1 Toprim domain Antiterm PF03589.13 EHU01330.1 - 8.1e-41 138.3 0.2 4.8e-22 78.1 0.0 2.6 2 1 0 2 2 2 2 Antitermination protein DnaJ_CXXCXGXG PF00684.19 EHU01330.1 - 2e-05 24.8 11.3 0.0081 16.5 8.0 3.0 1 1 1 2 2 2 2 DnaJ central domain Anti-TRAP PF15777.5 EHU01330.1 - 2.8 8.0 9.5 23 5.0 0.1 3.5 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF3716 PF12511.8 EHU01330.1 - 4.1 7.5 11.1 66 3.7 0.3 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3716) TerB PF05099.13 EHU01331.1 - 1.2e-15 57.7 4.4 2.6e-15 56.6 4.4 1.6 1 1 0 1 1 1 1 Tellurite resistance protein TerB DUF533 PF04391.12 EHU01331.1 - 1.3e-05 24.8 2.0 0.059 12.9 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF533) zf-HC2 PF13490.6 EHU01331.1 - 0.0024 18.1 6.7 0.029 14.6 0.0 2.9 3 0 0 3 3 3 2 Putative zinc-finger DUF3927 PF13064.6 EHU01332.1 - 5.1e-15 55.2 3.0 5.1e-15 55.2 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3927) DUF2371 PF10177.9 EHU01333.1 - 0.091 12.9 0.0 0.097 12.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Phage_lysozyme PF00959.19 EHU01334.1 - 4.8e-21 75.2 0.0 6.2e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Phage lysozyme Terpene_synth_C PF03936.16 EHU01335.1 - 0.066 12.6 0.1 0.072 12.4 0.1 1.1 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain DUF3232 PF11554.8 EHU01335.1 - 0.081 13.3 0.2 0.1 13.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3232) Conotoxin PF02950.17 EHU01335.1 - 0.18 12.9 3.4 0.4 11.7 0.3 2.2 1 1 1 2 2 2 0 Conotoxin LapA_dom PF06305.11 EHU01336.1 - 0.0037 17.0 3.0 0.0062 16.3 3.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide assembly protein A domain YtxH PF12732.7 EHU01336.1 - 3.5 8.2 6.1 30 5.2 6.1 2.0 1 1 0 1 1 1 0 YtxH-like protein EspB PF05802.11 EHU01337.1 - 0.033 14.2 0.6 0.036 14.0 0.6 1.0 1 0 0 1 1 1 0 Enterobacterial EspB protein Terminase_2 PF03592.16 EHU01339.1 - 1.1e-06 29.2 0.3 1.1e-06 29.2 0.3 1.7 2 0 0 2 2 2 1 Terminase small subunit HTH_29 PF13551.6 EHU01339.1 - 0.0094 16.0 0.1 6.4 6.9 0.0 2.9 3 0 0 3 3 3 2 Winged helix-turn helix HTH_23 PF13384.6 EHU01339.1 - 0.029 14.2 0.0 0.6 10.0 0.0 2.7 2 0 0 2 2 2 0 Homeodomain-like domain DFP PF04127.15 EHU01339.1 - 0.037 13.8 0.6 0.072 12.9 0.4 1.6 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Aromatic_hydrox PF11723.8 EHU01339.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Homotrimeric ring hydroxylase Terminase_3 PF04466.13 EHU01340.1 - 4.5e-38 130.8 0.0 5.7e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Phage terminase large subunit Terminase_3C PF17288.2 EHU01340.1 - 8.6e-09 36.0 0.0 2.5e-08 34.4 0.0 1.8 1 1 0 1 1 1 1 Terminase RNAseH like domain DUF1073 PF06381.11 EHU01341.1 - 4.8e-110 367.7 0.0 5.8e-110 367.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1073) Phage_integrase PF00589.22 EHU01342.1 - 1e-19 71.0 0.0 3.8e-19 69.1 0.0 1.9 2 0 0 2 2 2 1 Phage integrase family Arm-DNA-bind_3 PF13356.6 EHU01342.1 - 1.1e-15 57.7 0.1 2.9e-15 56.4 0.1 1.7 1 0 0 1 1 1 1 Arm DNA-binding domain SNase PF00565.17 EHU01342.1 - 0.034 14.6 0.2 4 7.9 0.0 2.4 2 0 0 2 2 2 0 Staphylococcal nuclease homologue Phage_AlpA PF05930.12 EHU01343.1 - 1.5e-07 31.1 0.1 1.9e-07 30.8 0.1 1.1 1 0 0 1 1 1 1 Prophage CP4-57 regulatory protein (AlpA) Phage_ASH PF10554.9 EHU01344.1 - 1.5e-29 102.4 0.1 2.6e-29 101.7 0.1 1.4 1 0 0 1 1 1 1 Ash protein family Phage_integrase PF00589.22 EHU01345.1 - 1.4e-09 38.0 0.2 4.9e-08 32.9 0.2 2.1 1 1 0 1 1 1 1 Phage integrase family Toprim_3 PF13362.6 EHU01347.1 - 3.1e-14 53.1 0.7 1.2e-13 51.2 0.7 2.1 1 0 0 1 1 1 1 Toprim domain Prim_Zn_Ribbon PF08273.12 EHU01347.1 - 9.8e-13 48.2 6.7 2e-12 47.2 6.7 1.5 1 0 0 1 1 1 1 Zinc-binding domain of primase-helicase Pox_D5 PF03288.16 EHU01347.1 - 1e-09 38.7 0.0 3.7e-09 37.0 0.0 2.0 2 0 0 2 2 2 1 Poxvirus D5 protein-like D5_N PF08706.11 EHU01347.1 - 1.2e-07 32.1 0.0 3.7e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 D5 N terminal like Toprim_2 PF13155.6 EHU01347.1 - 0.0002 21.7 0.3 0.00066 20.1 0.3 2.0 1 1 0 1 1 1 1 Toprim-like Zn_Tnp_IS1595 PF12760.7 EHU01347.1 - 0.00036 20.5 2.0 0.00076 19.4 2.0 1.5 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Toprim_4 PF13662.6 EHU01347.1 - 0.00067 20.1 0.1 0.0022 18.4 0.1 1.9 1 0 0 1 1 1 1 Toprim domain PALP PF00291.25 EHU01347.1 - 0.001 18.6 0.1 0.0018 17.8 0.1 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TF_Zn_Ribbon PF08271.12 EHU01347.1 - 0.0052 16.3 2.3 0.01 15.3 2.3 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding RFX_DNA_binding PF02257.15 EHU01347.1 - 0.014 16.0 0.1 0.032 14.8 0.1 1.6 1 0 0 1 1 1 0 RFX DNA-binding domain zf-CHC2 PF01807.20 EHU01347.1 - 0.023 14.5 0.0 0.068 13.0 0.0 1.7 1 0 0 1 1 1 0 CHC2 zinc finger Lar_restr_allev PF14354.6 EHU01347.1 - 0.038 14.4 0.6 0.11 12.8 0.6 1.8 1 0 0 1 1 1 0 Restriction alleviation protein Lar Nudix_N_2 PF14803.6 EHU01347.1 - 0.054 13.4 3.2 0.14 12.1 3.2 1.7 1 0 0 1 1 1 0 Nudix N-terminal AAA_29 PF13555.6 EHU01347.1 - 0.058 13.1 0.2 0.47 10.2 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain RhoGAP-FF1 PF16512.5 EHU01347.1 - 0.096 13.4 0.0 7.4 7.3 0.0 2.6 2 0 0 2 2 2 0 p190-A and -B Rho GAPs FF domain PhnA_Zn_Ribbon PF08274.12 EHU01347.1 - 0.15 12.0 0.2 0.34 10.9 0.2 1.6 1 0 0 1 1 1 0 PhnA Zinc-Ribbon zf-RRN7 PF11781.8 EHU01347.1 - 0.64 9.8 8.2 2.2 8.0 8.2 1.9 1 1 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 UPF0242 PF06785.11 EHU01349.1 - 0.17 12.0 5.2 0.2 11.8 5.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TPX2 PF06886.11 EHU01349.1 - 0.63 10.3 10.3 0.93 9.8 10.3 1.3 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) DNA_Packaging_2 PF11123.8 EHU01351.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 DNA packaging protein Gp138_N PF18352.1 EHU01353.1 - 9e-26 89.8 0.1 2.4e-25 88.5 0.1 1.7 2 0 0 2 2 2 1 Phage protein Gp138 N-terminal domain Phage_spike PF18715.1 EHU01353.1 - 2.9e-06 27.3 7.8 5.7e-06 26.3 7.8 1.5 1 0 0 1 1 1 1 Phage spike trimer FapA PF03961.13 EHU01353.1 - 0.16 10.6 2.1 0.2 10.2 2.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Terminase_2 PF03592.16 EHU01354.1 - 1.5e-18 67.6 0.4 1.8e-18 67.3 0.4 1.1 1 0 0 1 1 1 1 Terminase small subunit LTXXQ PF07813.12 EHU01354.1 - 0.49 11.1 3.6 5.4 7.8 0.3 2.6 2 2 0 2 2 2 0 LTXXQ motif family protein Phage_Mu_F PF04233.14 EHU01356.1 - 4.8e-15 56.3 0.1 9.8e-15 55.3 0.1 1.5 1 0 0 1 1 1 1 Phage Mu protein F like protein RsbRD_N PF14361.6 EHU01356.1 - 0.045 14.4 0.6 0.24 12.1 0.1 2.1 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain DUF5356 PF17309.2 EHU01356.1 - 0.13 12.2 0.1 0.23 11.4 0.1 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5356) HTH_Tnp_1 PF01527.20 EHU01357.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU01357.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU01357.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU01357.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHU01358.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHU01359.1 - 1.6e-86 290.3 4.8 5.1e-86 288.6 0.1 2.1 2 0 0 2 2 2 1 Transposase IS66 family zf-IS66 PF13005.7 EHU01359.1 - 6.3e-15 55.3 1.3 1.6e-14 54.0 1.3 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU01359.1 - 1.3e-11 45.1 9.6 2.8e-11 44.0 9.6 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHU01359.1 - 0.013 15.3 6.4 0.021 14.6 6.4 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Csm1_N PF18504.1 EHU01359.1 - 0.019 15.3 4.6 0.086 13.2 0.8 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Phage_HK97_TLTM PF06120.11 EHU01359.1 - 0.021 14.1 2.0 0.041 13.1 2.0 1.4 1 0 0 1 1 1 0 Tail length tape measure protein FUSC PF04632.12 EHU01359.1 - 0.022 13.3 6.9 0.044 12.3 6.9 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 EHU01359.1 - 0.023 14.3 2.0 0.03 13.9 0.6 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Tho2 PF11262.8 EHU01359.1 - 0.042 13.1 0.4 0.07 12.3 0.4 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Troponin PF00992.20 EHU01359.1 - 0.048 13.9 3.1 0.087 13.1 3.1 1.4 1 0 0 1 1 1 0 Troponin LXG PF04740.12 EHU01359.1 - 0.081 12.6 2.7 0.28 10.9 0.4 2.2 1 1 1 2 2 2 0 LXG domain of WXG superfamily UME PF08064.13 EHU01359.1 - 0.11 12.4 0.7 18 5.3 0.0 3.1 2 1 1 3 3 3 0 UME (NUC010) domain ERM PF00769.19 EHU01359.1 - 0.12 12.1 10.8 0.21 11.4 10.8 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DHR10 PF18595.1 EHU01359.1 - 0.29 11.2 10.9 0.53 10.4 10.9 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF1192 PF06698.11 EHU01359.1 - 0.31 11.1 5.3 2.9 8.0 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHU01359.1 - 0.9 8.7 3.1 1.4 8.1 3.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHU01359.1 - 2.1 7.9 7.8 4.8 6.7 7.8 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 HalX PF08663.10 EHU01359.1 - 2.6 8.4 6.9 0.48 10.8 3.1 1.7 2 0 0 2 2 1 0 HalX domain OmpH PF03938.14 EHU01359.1 - 2.7 8.3 8.0 5.7 7.3 8.0 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 EHU01359.1 - 4.6 7.9 8.8 9.8 6.9 1.7 3.2 1 1 1 2 2 2 0 SlyX DUF2213 PF09979.9 EHU01360.1 - 5.3e-47 159.9 0.0 1e-46 159.0 0.0 1.5 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2213) DUF2277 PF10041.9 EHU01360.1 - 0.0048 17.2 0.6 0.01 16.2 0.6 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2277) DUF2184 PF09950.9 EHU01362.1 - 4.5e-78 262.1 0.0 5.9e-78 261.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2184) DUF4054 PF13262.6 EHU01363.1 - 1.5e-30 105.3 0.1 1.8e-30 105.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4054) Phage_tail_S PF05069.13 EHU01364.1 - 0.00087 19.2 0.1 0.14 12.0 0.0 2.6 1 1 1 2 2 2 2 Phage virion morphogenesis family DUF3383 PF11863.8 EHU01367.1 - 4.2e-123 411.9 11.8 9.9e-101 338.1 6.3 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3383) DUF3277 PF11681.8 EHU01368.1 - 7.4e-66 220.5 1.4 8.1e-66 220.3 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3277) Methyltrn_RNA_3 PF02598.17 EHU01368.1 - 0.094 12.2 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Putative RNA methyltransferase Cas9_b_hairpin PF17893.1 EHU01369.1 - 0.11 12.3 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated endonuclease Cas9 beta-hairpin domain CUT PF02376.15 EHU01371.1 - 0.071 13.3 0.0 0.071 13.3 0.0 1.1 1 0 0 1 1 1 0 CUT domain TMP_2 PF06791.13 EHU01372.1 - 0.14 11.8 13.4 0.49 10.0 3.1 4.6 4 0 0 4 4 4 0 Prophage tail length tape measure protein Fmp27_WPPW PF10359.9 EHU01378.1 - 0.0003 19.8 0.1 0.00034 19.6 0.1 1.0 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain APG6_N PF17675.1 EHU01378.1 - 0.0022 18.5 1.4 0.0027 18.3 1.4 1.1 1 0 0 1 1 1 1 Apg6 coiled-coil region Cnn_1N PF07989.11 EHU01378.1 - 0.024 14.8 2.1 0.037 14.2 2.1 1.2 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Eapp_C PF10238.9 EHU01378.1 - 0.025 14.6 0.4 0.032 14.3 0.4 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein SKA1 PF07160.12 EHU01378.1 - 0.04 13.8 0.7 0.051 13.4 0.7 1.0 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DivIC PF04977.15 EHU01378.1 - 0.044 13.6 5.1 0.049 13.4 4.0 1.6 1 1 0 1 1 1 0 Septum formation initiator DUF2381 PF09544.10 EHU01378.1 - 0.045 13.3 0.1 0.05 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) CENP-H PF05837.12 EHU01378.1 - 0.047 14.1 1.0 0.057 13.8 1.0 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Mto2_bdg PF12808.7 EHU01378.1 - 0.08 13.2 0.6 0.12 12.7 0.6 1.3 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Sgf11 PF08209.11 EHU01378.1 - 0.32 10.6 0.1 0.32 10.6 0.1 1.9 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) bZIP_2 PF07716.15 EHU01378.1 - 0.4 10.8 4.0 0.5 10.5 2.0 1.9 1 1 1 2 2 2 0 Basic region leucine zipper Atg14 PF10186.9 EHU01378.1 - 3.5 6.6 6.1 1.3 8.1 1.4 2.0 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Gp138_N PF18352.1 EHU01379.1 - 2.3e-44 149.5 0.1 6.7e-44 148.0 0.0 1.8 2 0 0 2 2 2 1 Phage protein Gp138 N-terminal domain Baseplate_J PF04865.14 EHU01381.1 - 1.3e-18 67.1 8.2 1.6e-18 66.8 6.4 1.8 2 0 0 2 2 2 1 Baseplate J-like protein Oxidored_q6 PF01058.22 EHU01381.1 - 0.03 14.1 0.2 0.057 13.2 0.2 1.4 1 0 0 1 1 1 0 NADH ubiquinone oxidoreductase, 20 Kd subunit DUF2612 PF11041.8 EHU01382.1 - 2.3e-53 180.8 1.3 8.6e-50 169.2 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF2612) Caudo_TAP PF02413.17 EHU01384.1 - 9.2e-13 48.5 0.2 1e-12 48.3 0.2 1.0 1 0 0 1 1 1 1 Caudovirales tail fibre assembly protein, lambda gpK Phage_tail_APC PF16778.5 EHU01384.1 - 0.15 11.9 0.7 0.17 11.7 0.3 1.4 1 1 0 1 1 1 0 Phage tail assembly chaperone protein DUF2116 PF09889.9 EHU01385.1 - 0.047 13.7 0.7 0.07 13.1 0.7 1.3 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) zf-FLZ PF04570.14 EHU01385.1 - 0.13 11.7 0.2 0.13 11.7 0.2 1.7 2 0 0 2 2 2 0 zinc-finger of the FCS-type, C2-C2 DinI PF06183.13 EHU01386.1 - 2.7e-18 66.1 0.2 3.5e-18 65.7 0.2 1.1 1 0 0 1 1 1 1 DinI-like family DUF4994 PF16385.5 EHU01386.1 - 0.091 12.7 0.0 0.13 12.2 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function Peptidase_S24 PF00717.23 EHU01387.1 - 0.0019 18.1 0.0 0.009 16.0 0.0 1.8 1 1 1 2 2 2 1 Peptidase S24-like TetR_C_3 PF08362.11 EHU01388.1 - 1.8e-15 57.1 0.1 1.9e-15 57.1 0.1 1.0 1 0 0 1 1 1 1 YcdC-like protein, C-terminal region YdjM PF04307.14 EHU01389.1 - 1.3e-23 83.2 11.7 1.3e-23 83.2 11.7 1.5 2 0 0 2 2 2 1 LexA-binding, inner membrane-associated putative hydrolase DUF4131 PF13567.6 EHU01389.1 - 0.085 12.5 0.1 0.085 12.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) YhfC PF10086.9 EHU01389.1 - 0.18 11.1 2.0 1.3 8.3 0.0 2.2 2 0 0 2 2 2 0 YhfC intramembrane metalloprotease AA_permease PF00324.21 EHU01390.1 - 1.7e-111 373.2 51.3 1.9e-111 373.0 51.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EHU01390.1 - 1.6e-42 145.9 56.9 2.2e-42 145.4 56.9 1.0 1 0 0 1 1 1 1 Amino acid permease Extensin-like_C PF06904.12 EHU01391.1 - 1.5e-45 155.4 0.0 1.7e-45 155.3 0.0 1.0 1 0 0 1 1 1 1 Extensin-like protein C-terminus ZNRF_3_ecto PF18212.1 EHU01391.1 - 0.046 13.7 0.0 0.48 10.4 0.0 2.0 2 0 0 2 2 2 0 ZNRF-3 Ectodomain GerE PF00196.19 EHU01392.1 - 6.4e-15 54.4 0.1 7.8e-15 54.2 0.1 1.1 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_23 PF13384.6 EHU01392.1 - 0.00096 18.9 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 EHU01392.1 - 0.017 14.8 0.1 0.028 14.1 0.1 1.4 1 1 0 1 1 1 0 Sigma-70, region 4 DUF1617 PF07761.12 EHU01392.1 - 0.037 14.1 0.1 0.041 14.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1617) Sigma70_r4 PF04545.16 EHU01392.1 - 0.11 12.0 0.2 0.21 11.1 0.2 1.7 1 1 0 1 1 1 0 Sigma-70, region 4 Autoind_synth PF00765.17 EHU01393.1 - 1.2e-05 24.9 0.0 1.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Autoinducer synthase Acetyltransf_5 PF13444.6 EHU01393.1 - 0.0053 17.4 0.0 0.011 16.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2594 PF10769.9 EHU01394.1 - 2.1e-38 130.2 1.0 2.2e-38 130.1 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2594) Response_reg PF00072.24 EHU01395.1 - 2.9e-30 104.7 0.0 4.9e-30 104.0 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 EHU01395.1 - 1.9e-19 68.9 0.2 1.9e-19 68.9 0.2 2.2 3 0 0 3 3 3 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 EHU01395.1 - 5.1e-06 26.1 0.3 1.1e-05 25.0 0.1 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.6 EHU01395.1 - 0.00012 21.8 0.1 0.00044 20.0 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 EHU01395.1 - 0.0011 19.0 0.1 0.0047 16.9 0.0 2.1 3 0 0 3 3 3 1 Winged helix-turn helix HTH_Mga PF08280.11 EHU01395.1 - 0.0048 16.9 0.1 0.014 15.4 0.1 1.7 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain HTH_24 PF13412.6 EHU01395.1 - 0.005 16.4 0.1 0.013 15.0 0.1 1.8 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_7 PF02796.15 EHU01395.1 - 0.011 15.7 0.1 0.027 14.6 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_5 PF01022.20 EHU01395.1 - 0.035 14.0 0.1 0.11 12.4 0.1 1.9 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Sigma70_r4 PF04545.16 EHU01395.1 - 0.037 13.5 0.0 0.18 11.4 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 Terminase_5 PF06056.12 EHU01395.1 - 0.039 13.8 0.1 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) HTH_28 PF13518.6 EHU01395.1 - 0.045 13.9 0.0 0.18 11.9 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 EHU01395.1 - 0.053 12.9 0.0 0.2 11.1 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_40 PF14493.6 EHU01395.1 - 0.081 13.4 0.1 0.21 12.1 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_11 PF08279.12 EHU01395.1 - 0.13 12.2 0.3 0.42 10.6 0.1 2.0 2 0 0 2 2 1 0 HTH domain UvrC_HhH_N PF08459.11 EHU01396.1 - 5.4e-45 153.1 0.0 1.2e-44 151.9 0.0 1.6 1 0 0 1 1 1 1 UvrC Helix-hairpin-helix N-terminal GIY-YIG PF01541.24 EHU01396.1 - 1.4e-11 44.5 0.8 3e-11 43.4 0.3 1.9 2 0 0 2 2 2 1 GIY-YIG catalytic domain UVR PF02151.19 EHU01396.1 - 2.5e-09 36.6 1.2 5.7e-09 35.4 1.2 1.7 1 0 0 1 1 1 1 UvrB/uvrC motif HHH_5 PF14520.6 EHU01396.1 - 3.6e-08 33.9 0.0 9.6e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 EHU01396.1 - 1.9e-07 30.6 0.0 0.0067 16.2 0.0 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_3 PF12836.7 EHU01396.1 - 5.4e-07 29.8 0.7 0.22 11.8 0.1 3.5 3 0 0 3 3 3 2 Helix-hairpin-helix motif HHH_2 PF12826.7 EHU01396.1 - 1.3e-05 25.2 0.0 6.7e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif CDP-OH_P_transf PF01066.21 EHU01397.1 - 1.5e-16 60.9 0.8 1.5e-16 60.9 0.8 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Holin_2-3 PF13272.6 EHU01398.1 - 5e-39 132.8 1.0 5.6e-39 132.7 1.0 1.0 1 0 0 1 1 1 1 Putative 2/3 transmembrane domain holin ATPase_gene1 PF09527.10 EHU01398.1 - 0.012 15.7 0.4 0.74 10.0 0.0 2.5 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Transport_MerF PF11431.8 EHU01398.1 - 0.16 11.9 0.5 0.16 11.9 0.5 2.4 2 0 0 2 2 2 0 Membrane transport protein MerF DDE_Tnp_IS66 PF03050.14 EHU01400.1 - 2.8e-98 328.9 3.0 1.9e-97 326.1 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU01400.1 - 3.3e-16 59.2 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU01400.1 - 1.4e-14 54.2 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU01400.1 - 1.2e-11 45.2 9.0 2.6e-11 44.1 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHU01400.1 - 0.017 14.9 6.4 0.027 14.3 6.4 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Phage_HK97_TLTM PF06120.11 EHU01400.1 - 0.022 14.0 1.7 0.042 13.0 1.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHU01400.1 - 0.022 15.1 4.3 0.091 13.1 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain FUSC PF04632.12 EHU01400.1 - 0.038 12.5 6.8 0.06 11.9 6.8 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 EHU01400.1 - 0.04 13.5 2.2 0.047 13.2 0.8 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Tho2 PF11262.8 EHU01400.1 - 0.057 12.6 0.5 0.094 11.9 0.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Troponin PF00992.20 EHU01400.1 - 0.062 13.6 3.0 0.11 12.8 3.0 1.3 1 0 0 1 1 1 0 Troponin LXG PF04740.12 EHU01400.1 - 0.11 12.2 2.5 0.32 10.7 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily UME PF08064.13 EHU01400.1 - 0.15 12.0 0.5 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain ERM PF00769.19 EHU01400.1 - 0.16 11.8 10.8 0.26 11.1 10.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HalX PF08663.10 EHU01400.1 - 0.23 11.8 3.1 0.59 10.5 3.1 1.7 1 0 0 1 1 1 0 HalX domain DHR10 PF18595.1 EHU01400.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Zn-ribbon_8 PF09723.10 EHU01400.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF1192 PF06698.11 EHU01400.1 - 0.53 10.4 5.3 3.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHU01400.1 - 1.1 8.4 3.1 1.7 7.8 3.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHU01400.1 - 2.8 7.4 7.9 6.1 6.3 7.9 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHU01400.1 - 3.3 8.1 7.9 6.7 7.0 7.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 EHU01400.1 - 7.1 7.3 8.7 7.7 7.2 1.0 3.0 1 1 1 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHU01401.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHU01402.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU01402.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU01402.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU01402.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix CorA PF01544.18 EHU01403.1 - 1e-43 149.8 2.5 1.2e-43 149.5 2.5 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2207 PF09972.9 EHU01403.1 - 0.18 10.5 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ldt_C PF17969.1 EHU01404.1 - 1.7e-25 89.5 0.3 4.2e-25 88.3 0.3 1.7 1 0 0 1 1 1 1 L,D-transpeptidase C-terminal domain YkuD PF03734.14 EHU01404.1 - 1e-17 64.9 0.0 1.7e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain LysM PF01476.20 EHU01404.1 - 0.0038 17.3 0.0 0.0076 16.3 0.0 1.5 1 0 0 1 1 1 1 LysM domain Glyco_hydro_15 PF00723.21 EHU01405.1 - 5.4e-48 163.9 0.3 2.2e-46 158.6 0.3 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 Resolvase PF00239.21 EHU01406.1 - 6.8e-45 152.8 0.2 1e-44 152.2 0.2 1.2 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_7 PF02796.15 EHU01406.1 - 3.4e-13 49.4 0.1 1.5e-12 47.4 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 EHU01406.1 - 0.0071 16.1 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 EHU01406.1 - 0.014 16.0 0.2 0.026 15.1 0.2 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_38 PF13936.6 EHU01406.1 - 0.018 14.8 0.1 0.083 12.7 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_4 PF13613.6 EHU01406.1 - 0.022 14.5 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_29 PF13551.6 EHU01406.1 - 0.067 13.2 1.8 0.4 10.7 0.1 2.4 1 1 1 2 2 2 0 Winged helix-turn helix HTH_psq PF05225.16 EHU01406.1 - 0.069 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Caudo_TAP PF02413.17 EHU01407.1 - 1.3e-12 48.0 0.1 1.4e-12 47.9 0.1 1.0 1 0 0 1 1 1 1 Caudovirales tail fibre assembly protein, lambda gpK DUF469 PF04320.14 EHU01407.1 - 0.011 16.5 0.1 0.012 16.5 0.1 1.0 1 0 0 1 1 1 0 Protein with unknown function (DUF469) DAHP_synth_1 PF00793.20 EHU01408.1 - 8.4e-109 362.7 0.0 9.8e-109 362.5 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family His_Phos_1 PF00300.22 EHU01409.1 - 2.2e-37 128.6 0.1 4.8e-34 117.8 0.1 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Aldose_epim PF01263.20 EHU01410.1 - 6.4e-83 278.5 0.0 7.2e-83 278.3 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase GalKase_gal_bdg PF10509.9 EHU01411.1 - 5.9e-23 80.2 0.1 1.2e-22 79.1 0.1 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 EHU01411.1 - 6e-14 52.0 0.5 1.1e-13 51.2 0.5 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EHU01411.1 - 4.6e-12 46.1 0.1 1.4e-11 44.5 0.0 1.8 2 0 0 2 2 2 1 GHMP kinases C terminal Phage-tail_3 PF13550.6 EHU01411.1 - 0.15 11.9 1.4 0.15 11.9 0.1 1.6 2 0 0 2 2 2 0 Putative phage tail protein GalP_UDP_transf PF01087.22 EHU01412.1 - 5.5e-70 235.5 0.1 8.4e-70 234.9 0.1 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 EHU01412.1 - 5e-69 231.3 1.2 6.9e-69 230.9 0.2 1.7 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 EHU01412.1 - 0.00014 22.5 0.0 0.002 18.8 0.0 2.3 2 0 0 2 2 2 1 HIT domain ABC_tran PF00005.27 EHU01413.1 - 9.1e-51 172.0 0.0 1.5e-25 90.3 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EHU01413.1 - 1.6e-18 67.6 5.3 1.7e-07 31.4 0.3 4.2 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EHU01413.1 - 3e-08 33.3 0.0 0.0023 17.7 0.0 2.7 3 0 0 3 3 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 EHU01413.1 - 2.6e-07 30.3 0.8 0.19 11.2 0.0 3.5 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EHU01413.1 - 6.2e-07 29.5 0.0 0.2 11.6 0.0 3.3 2 1 1 3 3 3 2 RsgA GTPase AAA_23 PF13476.6 EHU01413.1 - 4.7e-06 27.3 0.9 0.065 13.7 0.1 2.4 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.6 EHU01413.1 - 2.4e-05 24.2 0.1 0.096 12.4 0.0 3.1 4 0 0 4 4 3 2 AAA ATPase domain AAA_22 PF13401.6 EHU01413.1 - 3.2e-05 24.2 3.0 0.43 10.9 0.1 3.8 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EHU01413.1 - 3.3e-05 24.1 0.1 0.096 12.8 0.0 3.0 4 0 0 4 4 2 2 AAA domain AAA_16 PF13191.6 EHU01413.1 - 4e-05 24.1 10.1 0.051 14.0 2.4 3.4 2 2 1 3 3 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 EHU01413.1 - 4.2e-05 23.6 0.2 0.26 11.4 0.0 3.2 3 1 0 3 3 3 2 50S ribosome-binding GTPase SbcCD_C PF13558.6 EHU01413.1 - 5.9e-05 23.2 0.1 0.048 13.9 0.3 3.5 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 EHU01413.1 - 9.6e-05 22.7 0.1 0.054 13.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EHU01413.1 - 0.00037 20.3 2.1 1.7 8.3 0.0 4.1 3 1 1 4 4 4 1 IstB-like ATP binding protein AAA_7 PF12775.7 EHU01413.1 - 0.00052 19.6 0.0 0.066 12.7 0.0 2.7 3 0 0 3 3 3 1 P-loop containing dynein motor region Dynamin_N PF00350.23 EHU01413.1 - 0.0009 19.3 0.0 0.05 13.7 0.0 2.3 2 0 0 2 2 2 1 Dynamin family Mg_chelatase PF01078.21 EHU01413.1 - 0.0021 17.4 0.0 0.069 12.5 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EHU01413.1 - 0.0035 17.9 0.0 0.55 10.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EHU01413.1 - 0.0041 17.5 0.1 0.79 10.2 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EHU01413.1 - 0.0087 15.7 0.1 0.89 9.1 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_27 PF13514.6 EHU01413.1 - 0.0092 15.6 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain Ploopntkinase1 PF18748.1 EHU01413.1 - 0.01 15.4 0.0 0.44 10.0 0.0 2.3 2 0 0 2 2 2 1 P-loop Nucleotide Kinase1 DUF3584 PF12128.8 EHU01413.1 - 0.012 13.2 0.0 0.15 9.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) HopA1 PF17914.1 EHU01413.1 - 0.021 14.6 0.0 0.5 10.1 0.0 2.4 2 0 0 2 2 2 0 HopA1 effector protein family NACHT PF05729.12 EHU01413.1 - 0.023 14.6 4.4 1.7 8.5 0.2 3.5 3 1 0 4 4 3 0 NACHT domain RNA_helicase PF00910.22 EHU01413.1 - 0.029 14.8 0.1 8.9 6.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.12 EHU01413.1 - 0.034 13.4 0.0 4.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_13 PF13166.6 EHU01413.1 - 0.13 10.9 0.0 4.4 5.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EHU01413.1 - 0.17 11.0 0.1 18 4.4 0.0 2.9 3 1 0 3 3 3 0 NB-ARC domain AAA_24 PF13479.6 EHU01413.1 - 0.18 11.5 0.0 12 5.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EHU01413.1 - 0.22 10.6 1.2 5.3 6.1 0.2 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF815) ATP_bind_1 PF03029.17 EHU01413.1 - 0.23 11.2 0.7 19 5.0 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein TOBE PF03459.17 EHU01414.1 - 2.3e-23 82.2 5.7 1.8e-12 47.4 0.5 2.8 3 0 0 3 3 3 2 TOBE domain HTH_1 PF00126.27 EHU01414.1 - 3.3e-13 49.4 0.4 8.9e-13 48.0 0.1 2.0 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family TOBE_2 PF08402.10 EHU01414.1 - 0.07 13.3 0.1 0.21 11.8 0.0 1.9 2 1 0 2 2 2 0 TOBE domain Sde2_N_Ubi PF13019.6 EHU01414.1 - 0.14 12.0 2.3 0.35 10.7 0.2 2.5 2 1 0 3 3 3 0 Silencing defective 2 N-terminal ubiquitin domain AcrZ PF10766.9 EHU01415.1 - 3.6e-29 100.1 1.3 3.9e-29 99.9 1.3 1.0 1 0 0 1 1 1 1 Multidrug efflux pump-associated protein AcrZ Insulin_TMD PF17870.1 EHU01415.1 - 0.09 12.9 2.7 0.11 12.6 2.7 1.1 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment SecE PF00584.20 EHU01415.1 - 0.24 11.3 2.1 0.29 11.1 2.1 1.1 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex SBP_bac_11 PF13531.6 EHU01416.1 - 1.1e-46 159.5 3.9 1.3e-46 159.2 3.9 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 EHU01416.1 - 4.5e-16 59.7 1.6 6.6e-16 59.1 1.6 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 EHU01416.1 - 0.019 14.4 1.0 0.2 11.0 0.2 2.2 1 1 1 2 2 2 0 Bacterial extracellular solute-binding protein FMO-like PF00743.19 EHU01416.1 - 0.15 10.4 0.0 0.2 10.0 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like BPD_transp_1 PF00528.22 EHU01417.1 - 7.5e-24 84.5 13.4 8.8e-24 84.2 13.4 1.1 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component DUF975 PF06161.11 EHU01417.1 - 0.064 13.0 0.9 0.2 11.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF975) Candida_ALS PF05792.13 EHU01417.1 - 0.49 11.0 1.9 26 5.5 0.2 2.4 2 0 0 2 2 2 0 Candida agglutinin-like (ALS) ABC_tran PF00005.27 EHU01418.1 - 9.9e-30 103.8 0.0 1.6e-29 103.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter TOBE PF03459.17 EHU01418.1 - 3.4e-16 59.3 0.3 4.3e-15 55.8 0.1 2.5 3 0 0 3 3 3 1 TOBE domain AAA_21 PF13304.6 EHU01418.1 - 6e-06 26.3 1.3 0.076 12.8 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EHU01418.1 - 0.00013 22.6 0.0 0.00019 22.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 EHU01418.1 - 0.00065 19.2 0.4 0.62 9.5 0.7 2.2 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EHU01418.1 - 0.0013 18.5 0.0 0.0044 16.7 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EHU01418.1 - 0.0021 18.0 0.0 0.0059 16.5 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 EHU01418.1 - 0.041 14.0 0.2 0.08 13.0 0.2 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 EHU01418.1 - 0.082 13.2 0.0 0.33 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 EHU01418.1 - 0.19 10.5 0.5 14 4.3 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Hydrolase_3 PF08282.12 EHU01419.1 - 4.4e-61 206.8 0.0 5e-61 206.7 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EHU01419.1 - 1.8e-13 50.6 0.0 2.4e-06 27.3 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 EHU01419.1 - 5.5e-09 36.6 0.4 0.0049 17.2 0.0 3.1 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase HAD PF12710.7 EHU01419.1 - 5.8e-07 30.1 1.7 0.0092 16.4 0.0 3.2 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EHU01419.1 - 4e-05 23.6 0.0 9.3e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EHU01419.1 - 0.14 12.2 0.2 33 4.5 0.0 2.8 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase Lar_N PF09861.9 EHU01419.1 - 0.14 11.3 0.2 0.24 10.5 0.2 1.2 1 0 0 1 1 1 0 Lactate racemase N-terminal domain Lactonase PF10282.9 EHU01420.1 - 4.6e-88 295.8 0.0 5.9e-88 295.4 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 EHU01420.1 - 7.6e-06 25.7 0.0 0.00056 19.6 0.0 2.4 1 1 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region DUF1513 PF07433.11 EHU01420.1 - 0.038 13.1 0.2 4.3 6.3 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) DUF4394 PF14339.6 EHU01420.1 - 0.088 12.2 0.0 0.67 9.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4394) PBP PF01161.20 EHU01421.1 - 5.1e-40 136.8 0.1 6.1e-40 136.6 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Aminotran_3 PF00202.21 EHU01422.1 - 3.9e-126 421.0 0.0 4.4e-126 420.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 EHU01422.1 - 0.02 14.2 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase JmjN PF02375.17 EHU01422.1 - 0.032 14.2 0.0 8.4 6.5 0.0 2.4 2 0 0 2 2 2 0 jmjN domain DUF4708 PF15813.5 EHU01422.1 - 0.054 12.7 0.5 0.62 9.2 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4708) Glyco_hydro_2_C PF02836.17 EHU01422.1 - 0.15 11.1 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain BATS PF06968.13 EHU01423.1 - 1e-20 73.7 0.0 2.2e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 EHU01423.1 - 3e-16 60.2 0.0 6.4e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Aminotran_1_2 PF00155.21 EHU01424.1 - 7.2e-57 193.2 0.0 8.2e-57 193.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EHU01424.1 - 0.0057 15.7 0.0 0.0089 15.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EHU01424.1 - 0.018 14.3 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EHU01424.1 - 0.024 13.9 0.0 0.048 13.0 0.0 1.5 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Methyltransf_11 PF08241.12 EHU01425.1 - 5.2e-25 87.9 0.0 1.3e-24 86.7 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EHU01425.1 - 9.2e-21 74.4 0.0 2.3e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EHU01425.1 - 2.2e-18 66.5 0.0 2.8e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EHU01425.1 - 1.1e-17 64.3 0.1 1.7e-17 63.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EHU01425.1 - 2.3e-12 47.5 0.0 6.2e-12 46.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EHU01425.1 - 3.7e-09 36.3 0.0 5e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 EHU01425.1 - 0.00088 18.7 0.0 0.0013 18.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.15 EHU01425.1 - 0.0014 18.5 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 EHU01425.1 - 0.0024 17.4 0.0 0.0046 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 EHU01425.1 - 0.016 14.2 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) CMAS PF02353.20 EHU01425.1 - 0.017 14.4 0.0 0.17 11.1 0.0 1.9 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 EHU01425.1 - 0.024 14.6 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_29 PF03141.16 EHU01425.1 - 0.024 13.2 0.0 0.034 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MetW PF07021.12 EHU01425.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW AAA_26 PF13500.6 EHU01426.1 - 2.4e-37 128.7 0.0 2.7e-37 128.5 0.0 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 EHU01426.1 - 2.2e-12 47.1 0.0 2.6e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1611 PF07755.11 EHU01426.1 - 6.3e-06 25.6 0.0 0.0017 17.7 0.1 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF1611_C) P-loop domain ABC_tran PF00005.27 EHU01427.1 - 1.4e-22 80.6 0.0 2.3e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 EHU01427.1 - 0.00025 21.4 0.1 0.0011 19.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EHU01427.1 - 0.0052 16.7 0.0 0.0076 16.2 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EHU01427.1 - 0.0078 16.6 0.2 0.02 15.3 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 EHU01427.1 - 0.017 15.2 0.1 0.036 14.2 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase TniB PF05621.11 EHU01427.1 - 0.032 13.7 0.3 2 7.8 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA PF00004.29 EHU01427.1 - 0.099 13.1 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EHU01427.1 - 0.14 12.6 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EHU01427.1 - 0.15 12.0 1.1 0.28 11.1 0.1 1.9 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 EHU01427.1 - 0.17 11.4 0.0 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EHU01427.1 - 0.2 11.6 0.3 0.33 10.8 0.3 1.3 1 0 0 1 1 1 0 NTPase UvrB_inter PF17757.1 EHU01428.1 - 2.6e-31 107.6 0.1 6.6e-31 106.3 0.1 1.8 1 0 0 1 1 1 1 UvrB interaction domain UvrB PF12344.8 EHU01428.1 - 5.5e-21 74.1 0.4 5.5e-21 74.1 0.4 2.1 2 0 0 2 2 2 1 Ultra-violet resistance protein B Helicase_C PF00271.31 EHU01428.1 - 1.1e-18 67.6 0.6 6.9e-18 65.0 0.1 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EHU01428.1 - 4.8e-10 39.7 0.0 3.8e-09 36.8 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UVR PF02151.19 EHU01428.1 - 2.9e-09 36.4 0.5 8.1e-09 34.9 0.5 1.9 1 0 0 1 1 1 1 UvrB/uvrC motif DEAD PF00270.29 EHU01428.1 - 0.0004 20.2 0.2 0.016 15.0 0.0 3.0 2 2 0 3 3 3 1 DEAD/DEAH box helicase AAA_30 PF13604.6 EHU01428.1 - 0.0065 16.2 0.0 0.034 13.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 EHU01428.1 - 0.012 15.7 0.6 0.15 12.2 0.0 2.8 2 1 0 2 2 2 0 Helicase HerA, central domain AAA_33 PF13671.6 EHU01428.1 - 0.026 14.7 0.0 0.62 10.2 0.0 2.7 2 2 0 2 2 2 0 AAA domain UB2H PF14814.6 EHU01428.1 - 0.044 13.8 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 Bifunctional transglycosylase second domain AAA_19 PF13245.6 EHU01428.1 - 0.046 14.1 0.0 6.9 7.0 0.0 2.7 2 1 0 2 2 2 0 AAA domain zf-C4H2 PF10146.9 EHU01428.1 - 2.3 8.5 5.6 0.24 11.7 0.6 1.9 2 0 0 2 2 1 0 Zinc finger-containing protein UPF0052 PF01933.18 EHU01429.1 - 1.2e-75 254.5 0.1 1.4e-75 254.3 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Mob_synth_C PF06463.13 EHU01430.1 - 4.8e-39 133.2 0.0 9.7e-39 132.2 0.0 1.5 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 EHU01430.1 - 9.5e-28 97.7 0.0 1.3e-27 97.3 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EHU01430.1 - 7.5e-08 32.7 0.0 1.8e-07 31.5 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EHU01430.1 - 0.00012 22.2 0.0 0.00024 21.2 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain MoCF_biosynth PF00994.24 EHU01431.1 - 3.3e-31 107.9 0.0 3.8e-31 107.7 0.0 1.0 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoaC PF01967.21 EHU01432.1 - 4.5e-55 185.5 0.9 5.2e-55 185.3 0.9 1.0 1 0 0 1 1 1 1 MoaC family ThiS PF02597.20 EHU01433.1 - 2.8e-19 69.5 0.0 3.2e-19 69.4 0.0 1.0 1 0 0 1 1 1 1 ThiS family DDE_5 PF13546.6 EHU01433.1 - 0.025 13.9 0.0 0.025 13.9 0.0 1.0 1 0 0 1 1 1 0 DDE superfamily endonuclease TGS PF02824.21 EHU01433.1 - 0.04 14.0 0.0 0.063 13.3 0.0 1.3 1 0 0 1 1 1 0 TGS domain DUF1586 PF07625.11 EHU01433.1 - 5.3 7.2 7.3 9.4 6.4 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1586) MoaE PF02391.17 EHU01434.1 - 3.2e-36 124.1 0.0 3.7e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 MoaE protein DUF1804 PF08822.11 EHU01434.1 - 0.013 15.5 0.2 1.5 8.7 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) Cu2_monoox_C PF03712.15 EHU01434.1 - 0.24 10.9 0.0 0.32 10.5 0.0 1.1 1 0 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, C-terminal domain DUF1264 PF06884.11 EHU01435.1 - 1.2e-70 236.6 0.0 1.4e-70 236.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) DUF1615 PF07759.12 EHU01436.1 - 2.5e-142 473.8 0.0 2.9e-142 473.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1615) Bax1-I PF01027.20 EHU01437.1 - 3.7e-59 200.0 33.7 4.1e-59 199.9 33.7 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 LPG_synthase_TM PF03706.13 EHU01438.1 - 5.9e-14 52.3 38.7 7.6e-14 51.9 38.7 1.1 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region EptA_B_N PF08019.12 EHU01438.1 - 8.8 6.2 14.7 1.1 9.1 3.1 2.8 2 1 1 3 3 3 0 Phosphoethanolamine transferase EptA/EptB PLDc_2 PF13091.6 EHU01439.1 - 8.9e-42 142.1 0.0 2.2e-25 89.1 0.0 2.1 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EHU01439.1 - 1.2e-08 34.8 1.6 1.5e-05 25.0 0.1 3.0 3 0 0 3 3 3 2 Phospholipase D Active site motif Regulator_TrmB PF11495.8 EHU01439.1 - 4.9e-06 25.9 0.0 0.00082 18.6 0.0 2.6 3 0 0 3 3 3 2 Archaeal transcriptional regulator TrmB PP_kinase_C PF13090.6 EHU01439.1 - 0.00028 20.4 0.3 0.21 11.0 0.1 2.7 2 1 0 2 2 2 2 Polyphosphate kinase C-terminal domain 2 YjcZ PF13990.6 EHU01439.1 - 0.072 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 YjcZ-like protein Exo_endo_phos PF03372.23 EHU01440.1 - 1.3e-13 51.1 0.6 1.9e-13 50.5 0.6 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family YbhQ PF11076.8 EHU01441.1 - 2e-60 202.6 7.2 2.2e-60 202.5 7.2 1.0 1 0 0 1 1 1 1 Putative inner membrane protein YbhQ YibE_F PF07907.11 EHU01441.1 - 0.00017 21.2 5.5 0.0002 21.0 5.5 1.1 1 0 0 1 1 1 1 YibE/F-like protein PSII_Ycf12 PF05969.11 EHU01441.1 - 0.022 14.8 1.3 0.022 14.8 1.3 1.8 2 0 0 2 2 2 0 Photosystem II complex subunit Ycf12 DUF3870 PF12986.7 EHU01441.1 - 0.057 13.7 0.1 0.072 13.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) CbbQ_C PF08406.10 EHU01441.1 - 0.1 12.8 0.2 0.14 12.4 0.2 1.2 1 0 0 1 1 1 0 CbbQ/NirQ/NorQ C-terminal TRAM_LAG1_CLN8 PF03798.16 EHU01441.1 - 0.15 11.8 6.6 0.22 11.3 6.6 1.3 1 1 0 1 1 1 0 TLC domain MerC PF03203.14 EHU01441.1 - 0.21 12.0 11.1 0.046 14.2 7.0 1.8 1 1 0 2 2 2 0 MerC mercury resistance protein DEAD PF00270.29 EHU01442.1 - 6.3e-51 172.6 0.0 1.3e-50 171.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EHU01442.1 - 2.8e-26 92.1 0.1 1.3e-25 89.9 0.0 2.0 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EHU01442.1 - 1.5e-05 25.1 0.0 3.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EHU01442.1 - 0.00023 21.5 0.0 0.12 12.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain UTP25 PF06862.12 EHU01442.1 - 0.0022 16.8 0.0 1.6 7.4 0.0 3.4 2 1 1 3 3 3 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 EHU01442.1 - 0.082 13.2 3.7 0.18 12.1 1.1 2.8 2 1 1 3 3 3 0 AAA domain UvrD-helicase PF00580.21 EHU01442.1 - 0.11 12.0 0.0 0.88 9.0 0.0 1.9 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain Dus PF01207.17 EHU01443.1 - 2.2e-89 299.6 0.0 2.6e-89 299.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 EHU01443.1 - 0.0054 16.2 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.15 EHU01443.1 - 0.0097 15.3 0.1 0.016 14.6 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase MR_MLE_C PF13378.6 EHU01443.1 - 0.025 14.2 0.3 0.091 12.3 0.3 2.0 1 1 0 1 1 1 0 Enolase C-terminal domain-like zf-CHC2 PF01807.20 EHU01443.1 - 0.14 12.0 0.0 5.1 7.0 0.0 2.8 3 0 0 3 3 3 0 CHC2 zinc finger PPK2 PF03976.14 EHU01444.1 - 5.9e-110 366.2 0.8 8e-110 365.8 0.8 1.1 1 0 0 1 1 1 1 Polyphosphate kinase 2 (PPK2) PHO4 PF01384.20 EHU01445.1 - 6.7e-88 295.0 6.9 1.4e-87 293.9 6.9 1.5 1 1 0 1 1 1 1 Phosphate transporter family DUF2627 PF11118.8 EHU01445.1 - 0.11 13.1 0.7 0.9 10.2 0.7 2.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) DDE_Tnp_ISL3 PF01610.17 EHU01446.1 - 1.4e-33 116.7 0.4 3.1e-19 69.6 0.0 2.2 2 0 0 2 2 2 2 Transposase zf-ISL3 PF14690.6 EHU01446.1 - 1.7e-06 28.6 7.4 1.7e-06 28.6 7.4 2.2 2 0 0 2 2 1 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HTH_29 PF13551.6 EHU01446.1 - 1.5e-05 24.9 0.8 4.7e-05 23.3 0.1 2.3 2 0 0 2 2 2 1 Winged helix-turn helix HTH_17 PF12728.7 EHU01446.1 - 0.00019 21.5 0.0 0.00088 19.4 0.0 2.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_7 PF02796.15 EHU01446.1 - 0.00039 20.4 0.6 0.0062 16.6 0.2 2.8 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 EHU01446.1 - 0.0036 17.0 3.7 0.02 14.7 0.5 3.6 3 0 0 3 3 3 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 EHU01446.1 - 0.01 15.5 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_38 PF13936.6 EHU01446.1 - 0.027 14.2 0.2 0.098 12.4 0.2 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_AlpA PF05930.12 EHU01446.1 - 0.028 14.2 0.0 0.073 12.9 0.0 1.6 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) MerR PF00376.23 EHU01446.1 - 0.035 13.9 0.1 0.1 12.4 0.1 1.8 1 0 0 1 1 1 0 MerR family regulatory protein HTH_28 PF13518.6 EHU01446.1 - 0.042 14.0 0.1 0.042 14.0 0.1 3.7 5 0 0 5 5 4 0 Helix-turn-helix domain HTH_IclR PF09339.10 EHU01446.1 - 0.062 13.1 0.0 0.36 10.7 0.0 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_AsnC-type PF13404.6 EHU01446.1 - 0.16 11.8 1.8 3.8 7.4 0.1 2.9 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain zf-IS66 PF13005.7 EHU01447.1 - 4.1e-15 55.9 1.5 1.1e-14 54.5 1.5 1.8 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU01447.1 - 4.7e-11 43.3 9.0 4.7e-11 43.3 9.0 2.2 2 1 0 2 2 2 1 Transposase C of IS166 homeodomain DDE_Tnp_IS66 PF03050.14 EHU01447.1 - 3.1e-10 40.0 5.9 1.6e-09 37.6 0.1 2.2 2 0 0 2 2 2 1 Transposase IS66 family Phage_HK97_TLTM PF06120.11 EHU01447.1 - 0.0034 16.6 0.7 0.0052 16.0 0.7 1.3 1 0 0 1 1 1 1 Tail length tape measure protein Csm1_N PF18504.1 EHU01447.1 - 0.0039 17.5 5.0 0.029 14.7 0.5 2.6 1 1 1 2 2 2 1 Csm1 N-terminal domain Exonuc_VII_L PF02601.15 EHU01447.1 - 0.0047 16.6 0.8 0.0054 16.4 0.8 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit Troponin PF00992.20 EHU01447.1 - 0.01 16.1 2.8 0.018 15.3 2.8 1.3 1 0 0 1 1 1 0 Troponin FAM184 PF15665.5 EHU01447.1 - 0.012 15.4 8.0 0.018 14.8 8.0 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B FUSC PF04632.12 EHU01447.1 - 0.013 14.1 7.4 0.015 13.8 7.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family ERM PF00769.19 EHU01447.1 - 0.019 14.8 9.7 0.027 14.3 9.7 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family LXG PF04740.12 EHU01447.1 - 0.024 14.3 3.2 0.1 12.3 0.5 2.2 1 1 1 2 2 2 0 LXG domain of WXG superfamily Tho2 PF11262.8 EHU01447.1 - 0.028 13.6 1.5 0.037 13.2 1.5 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Zn-ribbon_8 PF09723.10 EHU01447.1 - 0.067 13.3 1.8 0.39 10.9 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain DHR10 PF18595.1 EHU01447.1 - 0.092 12.8 10.9 0.16 12.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain RD3 PF14473.6 EHU01447.1 - 0.14 12.0 2.3 0.25 11.2 2.3 1.4 1 0 0 1 1 1 0 RD3 protein LCE6A PF15858.5 EHU01447.1 - 0.16 12.7 2.3 0.41 11.4 2.3 1.7 1 0 0 1 1 1 0 Late cornified envelope protein 6A family TMPIT PF07851.13 EHU01447.1 - 0.21 10.8 3.0 0.3 10.3 3.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHU01447.1 - 0.38 10.3 8.1 0.93 9.0 8.1 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF948 PF06103.11 EHU01447.1 - 0.42 10.9 1.5 29 5.0 0.2 2.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1192 PF06698.11 EHU01447.1 - 0.62 10.2 8.3 1.3 9.2 0.2 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF1192) Mt_ATP-synt_D PF05873.12 EHU01447.1 - 0.81 9.5 3.2 4.2 7.2 0.2 2.2 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) HalX PF08663.10 EHU01447.1 - 0.85 10.0 7.3 0.095 13.0 2.4 1.9 2 0 0 2 2 2 0 HalX domain USP8_interact PF08941.10 EHU01447.1 - 1.5 8.6 4.3 3.4 7.4 4.2 1.6 1 1 1 2 2 2 0 USP8 interacting OmpH PF03938.14 EHU01447.1 - 1.6 9.0 8.9 2.4 8.5 8.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 EHU01447.1 - 2 9.1 9.7 5.7 7.6 2.4 3.0 1 1 1 2 2 2 0 SlyX MerR-DNA-bind PF09278.11 EHU01447.1 - 2.2 8.9 9.9 3.7 8.2 0.5 2.6 2 0 0 2 2 2 0 MerR, DNA binding TMF_DNA_bd PF12329.8 EHU01447.1 - 3 7.9 8.8 3.2 7.8 0.7 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding TnpB_IS66 PF05717.13 EHU01448.1 - 1.7e-39 133.8 0.0 2e-39 133.6 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHU01449.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU01449.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU01449.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU01449.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TrbM PF07424.11 EHU01450.1 - 0.0018 18.3 0.0 0.0021 18.1 0.0 1.0 1 0 0 1 1 1 1 TrbM DUF4407 PF14362.6 EHU01451.1 - 0.0091 15.4 0.2 0.0095 15.3 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) YebO PF13974.6 EHU01451.1 - 0.028 14.5 0.8 0.037 14.1 0.8 1.1 1 0 0 1 1 1 0 YebO-like protein SlyX PF04102.12 EHU01451.1 - 0.041 14.5 1.9 0.054 14.1 1.9 1.2 1 0 0 1 1 1 0 SlyX Nup54 PF13874.6 EHU01451.1 - 0.051 13.7 1.1 0.059 13.5 1.1 1.1 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 FliD_C PF07195.12 EHU01451.1 - 0.083 12.3 0.5 0.092 12.1 0.5 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus RHH_3 PF12651.7 EHU01452.1 - 4.7e-15 55.3 0.0 5.5e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Ribbon-helix-helix domain FhuF PF06276.12 EHU01452.1 - 0.015 15.7 0.0 0.017 15.6 0.0 1.1 1 0 0 1 1 1 0 Ferric iron reductase FhuF-like transporter RHH_1 PF01402.21 EHU01452.1 - 0.019 14.9 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family Resolvase PF00239.21 EHU01453.1 - 2.2e-13 50.5 1.6 4.9e-13 49.4 1.6 1.6 1 1 0 1 1 1 1 Resolvase, N terminal domain HTH_7 PF02796.15 EHU01453.1 - 9.6e-06 25.6 1.1 0.00062 19.8 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 EHU01453.1 - 0.00018 21.2 0.1 0.00043 20.0 0.1 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 EHU01453.1 - 0.00058 19.2 0.1 0.0017 17.7 0.2 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 LacI PF00356.21 EHU01453.1 - 0.0046 16.7 0.6 0.0094 15.7 0.6 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family HTH_38 PF13936.6 EHU01453.1 - 0.0057 16.4 0.3 0.0057 16.4 0.3 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_28 PF13518.6 EHU01453.1 - 0.0097 16.0 1.3 0.013 15.6 0.1 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 EHU01453.1 - 0.013 15.8 0.0 0.032 14.5 0.0 1.6 1 0 0 1 1 1 0 Transposase HTH_6 PF01418.17 EHU01453.1 - 0.017 15.1 0.1 0.056 13.4 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family Sigma70_r4_2 PF08281.12 EHU01453.1 - 0.021 14.5 0.0 0.052 13.2 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_35 PF13693.6 EHU01453.1 - 0.029 14.4 0.5 0.051 13.6 0.1 1.6 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding AP_endonuc_2 PF01261.24 EHU01453.1 - 0.041 13.3 0.0 0.049 13.1 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel HTH_29 PF13551.6 EHU01453.1 - 0.098 12.7 2.3 0.11 12.5 0.1 2.3 3 0 0 3 3 3 0 Winged helix-turn helix HTH_22 PF13309.6 EHU01453.1 - 0.15 12.2 0.9 2.9 8.0 0.2 2.8 2 1 1 3 3 3 0 HTH domain HTH_31 PF13560.6 EHU01453.1 - 2 8.8 8.4 7.9 6.9 6.7 2.6 2 1 0 2 2 2 0 Helix-turn-helix domain RepA_C PF04796.12 EHU01454.1 - 1.1e-29 103.5 0.0 1.5e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 Plasmid encoded RepA protein KORA PF16509.5 EHU01455.1 - 8.5e-25 86.9 0.1 1e-24 86.6 0.1 1.1 1 0 0 1 1 1 1 TrfB plasmid transcriptional repressor GerE PF00196.19 EHU01455.1 - 0.052 13.1 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 EHU01455.1 - 0.098 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 SSB PF00436.25 EHU01456.1 - 2.1e-40 137.0 0.5 2.5e-40 136.7 0.5 1.1 1 0 0 1 1 1 1 Single-strand binding protein family DUF4792 PF16040.5 EHU01456.1 - 0.16 11.9 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4792) SprT-like PF10263.9 EHU01457.1 - 3.8e-11 42.9 0.0 5.7e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 SprT-like family Peptidase_M91 PF14891.6 EHU01457.1 - 0.026 14.8 0.0 0.11 12.8 0.0 1.8 2 0 0 2 2 2 0 Effector protein Antirestrict PF03230.13 EHU01458.1 - 1.5e-08 34.5 0.1 2.3e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 Antirestriction protein RVT_1 PF00078.27 EHU01461.1 - 5.9e-43 146.9 0.0 1.4e-42 145.7 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) GIIM PF08388.11 EHU01461.1 - 1.4e-15 57.1 2.1 3.2e-15 56.0 2.1 1.6 1 0 0 1 1 1 1 Group II intron, maturase-specific domain Pentapeptide PF00805.22 EHU01462.1 - 5.4e-09 35.5 7.1 7.8e-06 25.4 0.4 2.5 1 1 1 2 2 2 2 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 EHU01462.1 - 1.4e-05 25.1 0.9 5.8e-05 23.2 0.4 2.2 2 1 0 2 2 2 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 EHU01462.1 - 0.00047 20.3 1.5 0.0013 18.9 1.5 1.8 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) Zn_Tnp_IS1 PF03811.13 EHU01463.1 - 3.7e-23 80.9 8.6 4.2e-23 80.8 8.6 1.0 1 0 0 1 1 1 1 InsA N-terminal domain DpnI PF06044.12 EHU01463.1 - 0.0008 19.1 0.3 0.00085 19.0 0.3 1.0 1 0 0 1 1 1 1 Dam-replacing family Zn_Tnp_IS1595 PF12760.7 EHU01463.1 - 0.0011 18.9 4.7 0.0014 18.5 4.7 1.2 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zinc-ribbons_6 PF07191.12 EHU01463.1 - 0.0018 18.2 0.7 0.0023 17.9 0.7 1.1 1 0 0 1 1 1 1 zinc-ribbons Zn-ribbon_8 PF09723.10 EHU01463.1 - 0.0027 17.8 2.7 0.94 9.6 0.6 2.2 2 0 0 2 2 2 2 Zinc ribbon domain C1_1 PF00130.22 EHU01463.1 - 0.0028 17.5 0.9 0.0035 17.2 0.9 1.1 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C4_Topoisom PF01396.19 EHU01463.1 - 0.0063 16.3 0.1 0.0063 16.3 0.1 1.4 1 1 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger Zn_ribbon_recom PF13408.6 EHU01463.1 - 0.0069 16.9 1.8 0.0083 16.6 1.8 1.1 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain PhnA_Zn_Ribbon PF08274.12 EHU01463.1 - 0.014 15.3 0.1 0.02 14.8 0.1 1.2 1 0 0 1 1 1 0 PhnA Zinc-Ribbon zinc_ribbon_4 PF13717.6 EHU01463.1 - 0.018 14.9 5.5 0.051 13.5 5.5 1.7 1 1 0 1 1 1 0 zinc-ribbon domain RNA_POL_M_15KD PF02150.16 EHU01463.1 - 0.023 14.5 0.2 0.031 14.2 0.2 1.2 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit TackOD1 PF18551.1 EHU01463.1 - 0.027 14.2 0.9 0.028 14.1 0.9 1.1 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 VP_N-CPKC PF11475.8 EHU01463.1 - 0.058 13.3 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Virion protein N terminal domain TRAF6_Z2 PF18048.1 EHU01463.1 - 0.063 13.4 3.1 0.43 10.7 0.3 2.2 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 zf-ISL3 PF14690.6 EHU01463.1 - 0.075 13.7 0.8 0.075 13.7 0.8 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 C1_4 PF07975.12 EHU01463.1 - 0.077 13.2 2.7 0.56 10.5 3.0 1.9 1 1 1 2 2 2 0 TFIIH C1-like domain zinc_ribbon_12 PF11331.8 EHU01463.1 - 0.085 12.7 1.1 0.55 10.1 1.2 1.9 1 1 0 1 1 1 0 Probable zinc-ribbon domain DiS_P_DiS PF06750.13 EHU01463.1 - 0.091 12.9 0.8 9.3 6.4 0.1 2.0 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain Nudix_N_2 PF14803.6 EHU01463.1 - 0.13 12.2 6.4 0.23 11.4 6.4 1.3 1 1 0 1 1 1 0 Nudix N-terminal zf-Dof PF02701.15 EHU01463.1 - 0.23 11.6 7.2 0.56 10.4 7.2 1.6 1 1 0 1 1 1 0 Dof domain, zinc finger HypA PF01155.19 EHU01463.1 - 0.27 11.3 1.7 14 5.8 0.1 1.9 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-TFIIB PF13453.6 EHU01463.1 - 0.38 10.1 4.7 0.68 9.3 4.7 1.5 1 1 0 1 1 1 0 Transcription factor zinc-finger Mu-like_Com PF10122.9 EHU01463.1 - 0.47 9.9 5.6 3.3 7.2 0.3 2.1 1 1 1 2 2 2 0 Mu-like prophage protein Com DDE_3 PF13358.6 EHU01464.1 - 1.1e-22 80.3 0.0 1.9e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 EHU01464.1 - 1e-10 41.1 1.0 3.6e-09 36.2 0.1 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 EHU01464.1 - 5.2e-09 36.6 1.2 3.5e-08 34.0 0.3 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 EHU01464.1 - 1.7e-07 31.1 0.6 6.1e-07 29.4 0.1 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_33 PF13592.6 EHU01464.1 - 4.4e-06 26.2 0.3 4.4e-06 26.2 0.3 3.4 4 0 0 4 4 4 1 Winged helix-turn helix HTH_28 PF13518.6 EHU01464.1 - 1.3e-05 25.2 0.2 0.0002 21.4 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHU01464.1 - 0.052 13.3 0.6 0.16 11.8 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHU01464.1 - 0.056 14.0 0.2 0.11 13.0 0.2 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 HTH_Tnp_IS1 PF12759.7 EHU01465.1 - 9e-32 108.4 0.3 1.1e-31 108.2 0.3 1.1 1 0 0 1 1 1 1 InsA C-terminal domain HTH_Tnp_ISL3 PF13542.6 EHU01465.1 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Sigma70_ECF PF07638.11 EHU01465.1 - 0.06 13.2 0.0 0.062 13.2 0.0 1.1 1 0 0 1 1 1 0 ECF sigma factor TnsD PF15978.5 EHU01465.1 - 0.12 11.3 0.0 0.12 11.3 0.0 1.0 1 0 0 1 1 1 0 Tn7-like transposition protein D DDE_Tnp_IS1 PF03400.13 EHU01466.1 - 2.2e-44 151.0 0.0 2.5e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 IS1 transposase DDE_Tnp_IS66 PF03050.14 EHU01466.1 - 0.0012 18.4 0.0 0.0013 18.3 0.0 1.0 1 0 0 1 1 1 1 Transposase IS66 family DDE_Tnp_IS1 PF03400.13 EHU01467.1 - 2.3e-25 89.4 0.9 2.4e-25 89.4 0.9 1.0 1 0 0 1 1 1 1 IS1 transposase Curto_V2 PF07325.11 EHU01467.1 - 0.06 13.2 0.1 0.06 13.2 0.1 1.2 1 0 0 1 1 1 0 Curtovirus V2 protein Resolvase PF00239.21 EHU01468.1 - 1.8e-27 96.3 1.1 3.4e-27 95.4 1.1 1.5 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_7 PF02796.15 EHU01468.1 - 0.019 15.1 0.6 0.076 13.1 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 EHU01468.1 - 0.02 14.6 0.1 0.059 13.2 0.1 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_3 PF01381.22 EHU01468.1 - 0.74 9.9 4.8 2.2 8.4 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix AAA_31 PF13614.6 EHU01470.1 - 5.4e-39 133.9 0.1 8.3e-39 133.3 0.1 1.2 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 EHU01470.1 - 6.7e-15 55.3 0.1 8.8e-15 54.9 0.1 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 EHU01470.1 - 4.9e-07 29.3 0.7 0.00013 21.3 0.1 2.5 2 1 0 2 2 2 2 ATPase MipZ CBP_BcsQ PF06564.12 EHU01470.1 - 1e-06 28.5 0.0 2.6e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ArsA_ATPase PF02374.15 EHU01470.1 - 3e-06 26.6 0.3 7.6e-06 25.3 0.3 1.8 1 1 0 1 1 1 1 Anion-transporting ATPase ParA PF10609.9 EHU01470.1 - 0.0001 21.8 1.2 0.0015 18.0 0.0 2.2 2 1 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase VirC1 PF07015.11 EHU01470.1 - 0.0015 17.9 0.5 0.017 14.4 0.1 2.1 2 0 0 2 2 2 1 VirC1 protein DDE_Tnp_IS66 PF03050.14 EHU01471.1 - 5.4e-98 327.9 6.0 3.5e-97 325.2 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU01471.1 - 7.5e-18 64.5 0.1 3.1e-17 62.5 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU01471.1 - 1.4e-14 54.2 1.5 3.3e-14 53.0 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU01471.1 - 1e-10 42.2 8.3 2.2e-10 41.1 8.3 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FUSC PF04632.12 EHU01471.1 - 0.0075 14.9 5.3 0.012 14.2 5.3 1.3 1 0 0 1 1 1 1 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 EHU01471.1 - 0.028 14.0 2.4 0.032 13.8 0.9 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Phage_HK97_TLTM PF06120.11 EHU01471.1 - 0.062 12.5 1.8 0.12 11.5 1.8 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHU01471.1 - 0.069 13.5 4.5 0.9 9.9 0.2 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain PRA-PH PF01503.17 EHU01471.1 - 0.095 13.1 0.4 11 6.5 0.1 2.7 3 0 0 3 3 2 0 Phosphoribosyl-ATP pyrophosphohydrolase Tho2 PF11262.8 EHU01471.1 - 0.14 11.3 0.7 0.23 10.6 0.7 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DHR10 PF18595.1 EHU01471.1 - 0.21 11.7 10.7 0.36 10.9 10.7 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain MIS13 PF08202.11 EHU01471.1 - 0.21 10.8 4.1 0.22 10.8 3.1 1.4 2 0 0 2 2 2 0 Mis12-Mtw1 protein family TSNAXIP1_N PF15739.5 EHU01471.1 - 0.35 11.3 3.7 0.79 10.1 3.7 1.5 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus HHH_8 PF14716.6 EHU01471.1 - 0.41 11.0 4.5 0.6 10.5 2.0 2.5 2 1 0 2 2 2 0 Helix-hairpin-helix domain LXG PF04740.12 EHU01471.1 - 0.45 10.2 3.3 0.75 9.5 0.3 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily Zn-ribbon_8 PF09723.10 EHU01471.1 - 0.52 10.5 2.3 0.95 9.6 0.2 2.3 2 0 0 2 2 2 0 Zinc ribbon domain ERM PF00769.19 EHU01471.1 - 0.69 9.7 12.2 1.1 9.0 12.2 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family TMPIT PF07851.13 EHU01471.1 - 2.5 7.3 3.9 3.8 6.7 3.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein OmpH PF03938.14 EHU01471.1 - 5.4 7.4 8.3 12 6.3 8.3 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HAUS-augmin3 PF14932.6 EHU01471.1 - 6.8 6.2 8.7 17 4.8 8.7 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 SlyX PF04102.12 EHU01471.1 - 7.6 7.2 9.0 12 6.6 1.7 3.1 1 1 1 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHU01472.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_33 PF13592.6 EHU01474.1 - 3.8e-17 61.7 0.0 7.5e-17 60.7 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix DDE_3 PF13358.6 EHU01474.1 - 1.7e-09 37.6 0.0 4.9e-09 36.1 0.0 1.8 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.6 EHU01474.1 - 5.4e-06 26.3 0.1 1.4e-05 25.0 0.1 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 EHU01474.1 - 0.021 14.6 0.0 0.054 13.3 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain rve PF00665.26 EHU01475.1 - 2.3e-30 105.2 0.1 3.4e-30 104.7 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 EHU01475.1 - 5e-09 35.8 0.1 9e-09 35.0 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 EHU01475.1 - 1.2e-08 35.2 0.0 1.8e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 DDE domain HTH_21 PF13276.6 EHU01475.1 - 0.00034 20.7 0.0 0.00085 19.4 0.0 1.6 1 0 0 1 1 1 1 HTH-like domain rve_2 PF13333.6 EHU01475.1 - 0.012 15.8 0.0 0.026 14.7 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Y2_Tnp PF04986.13 EHU01477.1 - 1e-40 139.8 0.4 1.4e-40 139.3 0.4 1.1 1 0 0 1 1 1 1 Putative transposase DDE_Tnp_IS66_C PF13817.6 EHU01478.1 - 3e-17 62.5 0.1 4.4e-17 62.0 0.1 1.3 1 0 0 1 1 1 1 IS66 C-terminal element Transposase_31 PF04754.12 EHU01479.1 - 5.6e-86 287.4 0.0 7.8e-86 286.9 0.0 1.2 1 0 0 1 1 1 1 Putative transposase, YhgA-like Yae1_N PF09811.9 EHU01479.1 - 0.0053 16.4 4.1 0.0098 15.6 4.1 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Glyco_trans_4_3 PF12000.8 EHU01479.1 - 0.026 14.2 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 4 group DUF2267 PF10025.9 EHU01479.1 - 0.16 12.3 2.0 0.95 9.8 0.2 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) DUF2913 PF11140.8 EHU01480.1 - 1.9e-20 73.5 0.0 2.4e-20 73.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2913) DUF4131 PF13567.6 EHU01482.1 - 1.2 8.7 6.1 1.2 8.8 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) HTH_Tnp_1 PF01527.20 EHU01483.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU01483.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU01483.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU01483.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHU01484.1 - 7.4e-39 131.7 0.0 8.3e-39 131.6 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHU01485.1 - 9e-98 327.2 4.0 3.2e-97 325.4 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU01485.1 - 3.2e-16 59.3 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU01485.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU01485.1 - 1.2e-11 45.1 9.0 2.6e-11 44.1 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHU01485.1 - 0.017 14.9 6.4 0.027 14.3 6.4 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Phage_HK97_TLTM PF06120.11 EHU01485.1 - 0.021 14.0 1.7 0.042 13.0 1.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHU01485.1 - 0.022 15.1 4.3 0.091 13.1 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain FUSC PF04632.12 EHU01485.1 - 0.038 12.6 6.8 0.06 11.9 6.8 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 EHU01485.1 - 0.04 13.5 2.2 0.047 13.2 0.8 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Tho2 PF11262.8 EHU01485.1 - 0.057 12.6 0.5 0.094 11.9 0.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Troponin PF00992.20 EHU01485.1 - 0.062 13.6 3.0 0.11 12.8 3.0 1.3 1 0 0 1 1 1 0 Troponin LXG PF04740.12 EHU01485.1 - 0.11 12.3 2.5 0.32 10.7 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily UME PF08064.13 EHU01485.1 - 0.15 12.0 0.5 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain ERM PF00769.19 EHU01485.1 - 0.16 11.8 10.8 0.26 11.1 10.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HalX PF08663.10 EHU01485.1 - 0.23 11.8 3.1 0.59 10.5 3.1 1.7 1 0 0 1 1 1 0 HalX domain DHR10 PF18595.1 EHU01485.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Zn-ribbon_8 PF09723.10 EHU01485.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF1192 PF06698.11 EHU01485.1 - 0.53 10.4 5.3 3.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHU01485.1 - 1.1 8.4 3.1 1.7 7.8 3.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHU01485.1 - 2.8 7.4 7.9 6.1 6.3 7.9 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHU01485.1 - 3.3 8.1 7.9 6.7 7.0 7.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 EHU01485.1 - 7.2 7.3 8.7 7.7 7.2 1.0 3.0 1 1 1 2 2 2 0 SlyX CN_hydrolase PF00795.22 EHU01486.1 - 1.1e-34 119.9 0.0 1.6e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CorC_HlyC PF03471.17 EHU01487.1 - 3.6e-22 78.2 0.0 3.6e-22 78.2 0.0 2.2 3 0 0 3 3 3 1 Transporter associated domain CBS PF00571.28 EHU01487.1 - 1.9e-15 57.0 3.8 6.3e-08 33.0 0.1 2.9 3 0 0 3 3 3 2 CBS domain DUF1108 PF06531.11 EHU01487.1 - 0.071 13.4 0.3 2.2 8.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1108) UPF0054 PF02130.17 EHU01488.1 - 4.7e-41 139.6 0.0 5.5e-41 139.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 DUF1462 PF07315.11 EHU01488.1 - 0.04 14.2 0.0 0.07 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) PhoH PF02562.16 EHU01489.1 - 9.6e-96 319.1 0.0 1.2e-95 318.8 0.0 1.1 1 0 0 1 1 1 1 PhoH-like protein AAA_30 PF13604.6 EHU01489.1 - 2e-09 37.5 0.0 3.2e-09 36.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EHU01489.1 - 8.9e-05 22.9 0.1 0.0003 21.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EHU01489.1 - 0.002 17.9 0.0 0.0057 16.4 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein DEAD PF00270.29 EHU01489.1 - 0.0024 17.7 0.0 0.0066 16.2 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EHU01489.1 - 0.0055 17.0 0.0 0.015 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EHU01489.1 - 0.01 15.4 0.0 0.024 14.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain Zot PF05707.12 EHU01489.1 - 0.059 13.0 0.0 6.1 6.4 0.0 2.3 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) UPF0004 PF00919.20 EHU01490.1 - 2.9e-30 104.2 0.0 5.3e-30 103.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 EHU01490.1 - 4.7e-28 98.7 0.0 7.5e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily TRAM PF01938.20 EHU01490.1 - 9.5e-19 67.2 0.7 2.1e-18 66.1 0.7 1.6 1 0 0 1 1 1 1 TRAM domain TRAM_2 PF18693.1 EHU01490.1 - 0.022 14.9 0.5 0.079 13.1 0.5 2.0 1 1 0 1 1 1 0 TRAM domain L_protein_N PF15518.6 EHU01490.1 - 0.033 14.0 0.0 0.07 13.0 0.0 1.5 1 0 0 1 1 1 0 L protein N-terminus B12-binding PF02310.19 EHU01490.1 - 0.034 14.2 0.1 0.34 11.0 0.0 2.5 3 0 0 3 3 3 0 B12 binding domain FAD_binding_3 PF01494.19 EHU01491.1 - 2.1e-27 96.3 0.0 2.7e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EHU01491.1 - 2e-09 37.5 1.4 4.5e-06 26.5 0.1 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EHU01491.1 - 5.9e-08 32.3 0.0 0.00074 18.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EHU01491.1 - 2e-07 30.4 1.8 9.9e-07 28.1 1.8 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EHU01491.1 - 1.2e-05 25.4 0.1 3.7e-05 23.9 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EHU01491.1 - 5.8e-05 23.6 0.0 0.00073 20.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EHU01491.1 - 0.00013 20.9 0.0 0.57 9.0 0.0 2.8 2 1 0 2 2 2 2 Tryptophan halogenase NAD_binding_9 PF13454.6 EHU01491.1 - 0.0013 18.8 0.4 0.048 13.7 0.4 2.3 1 1 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EHU01491.1 - 0.0018 17.4 0.6 0.0043 16.2 0.6 1.6 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 EHU01491.1 - 0.0025 16.9 0.0 0.0048 16.0 0.0 1.5 2 0 0 2 2 2 1 Squalene epoxidase Thi4 PF01946.17 EHU01491.1 - 0.013 14.8 0.0 0.036 13.3 0.0 1.7 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 EHU01491.1 - 0.031 13.0 1.1 0.36 9.5 0.3 2.1 2 0 0 2 2 2 0 HI0933-like protein Mqo PF06039.15 EHU01491.1 - 0.13 10.8 0.0 4.7 5.7 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) 3HCDH_N PF02737.18 EHU01491.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EHU01491.1 - 0.17 12.3 0.1 0.36 11.3 0.1 1.7 2 1 0 2 2 1 0 Putative NAD(P)-binding FAD_oxidored PF12831.7 EHU01491.1 - 0.86 8.9 2.5 3.7 6.8 1.7 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Asn_synthase PF00733.21 EHU01492.1 - 2.5e-102 343.2 0.4 4.5e-59 200.9 0.2 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 EHU01492.1 - 1.9e-42 144.1 0.0 3.1e-42 143.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EHU01492.1 - 1.2e-36 125.8 0.0 2.8e-36 124.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EHU01492.1 - 5.4e-09 35.8 0.0 1.1e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 EHU01492.1 - 0.16 11.1 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 NAD synthase Hydrolase_6 PF13344.6 EHU01493.1 - 2.9e-24 85.1 0.0 5.8e-24 84.1 0.0 1.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EHU01493.1 - 5.5e-21 74.4 0.0 1.3e-20 73.2 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 EHU01493.1 - 8.1e-13 49.1 0.0 1.2e-12 48.6 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EHU01493.1 - 2.5e-10 40.7 0.0 9.4e-08 32.3 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HAD PF12710.7 EHU01493.1 - 0.061 13.7 0.0 0.32 11.4 0.0 2.1 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase ROK PF00480.20 EHU01494.1 - 3.6e-91 305.7 0.7 4.5e-91 305.4 0.7 1.1 1 0 0 1 1 1 1 ROK family MarR PF01047.22 EHU01494.1 - 2.7e-07 30.4 0.0 9.2e-07 28.7 0.0 1.9 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 EHU01494.1 - 7e-05 22.3 0.4 0.00053 19.5 0.2 2.2 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 EHU01494.1 - 0.0003 20.6 0.3 0.00086 19.1 0.3 1.8 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 EHU01494.1 - 0.0011 18.9 0.1 0.0025 17.8 0.1 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Fe_dep_repress PF01325.19 EHU01494.1 - 0.0019 18.3 0.0 0.0044 17.2 0.0 1.6 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain SMC_ScpB PF04079.16 EHU01494.1 - 0.0075 15.9 0.3 0.018 14.7 0.1 1.7 2 0 0 2 2 2 1 Segregation and condensation complex subunit ScpB HTH_IclR PF09339.10 EHU01494.1 - 0.036 13.8 0.0 0.092 12.6 0.0 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain Amidohydro_1 PF01979.20 EHU01495.1 - 6.9e-47 160.4 1.3 8.1e-47 160.2 1.3 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EHU01495.1 - 5.8e-07 29.3 0.1 6.7e-06 25.8 0.0 2.3 3 0 0 3 3 3 1 Amidohydrolase family Glucosamine_iso PF01182.20 EHU01496.1 - 1.1e-20 74.5 0.0 1.6e-20 74.0 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase PTS_EIIC PF02378.18 EHU01497.1 - 5.7e-76 255.6 33.8 1e-75 254.7 33.8 1.5 1 0 0 1 1 1 1 Phosphotransferase system, EIIC PTS_EIIA_1 PF00358.20 EHU01497.1 - 1.9e-47 160.2 0.5 4e-47 159.1 0.5 1.6 1 0 0 1 1 1 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 PTS_EIIB PF00367.20 EHU01497.1 - 9.8e-13 47.4 0.5 2e-12 46.3 0.5 1.6 1 0 0 1 1 1 1 phosphotransferase system, EIIB RnfC_N PF13375.6 EHU01497.1 - 0.0029 17.6 0.7 5.8 6.9 0.0 3.5 2 1 1 3 3 3 1 RnfC Barrel sandwich hybrid domain Peptidase_M23 PF01551.22 EHU01497.1 - 0.013 15.7 0.1 0.041 14.1 0.1 1.9 1 0 0 1 1 1 0 Peptidase family M23 Biotin_lipoyl PF00364.22 EHU01497.1 - 0.1 12.4 0.1 6.7 6.6 0.0 2.9 2 0 0 2 2 2 0 Biotin-requiring enzyme tRNA-synt_1c PF00749.21 EHU01498.1 - 1.1e-126 422.0 0.0 1.3e-126 421.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EHU01498.1 - 2.8e-62 209.7 0.0 7.7e-62 208.2 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain FUR PF01475.19 EHU01500.1 - 3.4e-47 159.5 0.3 3.9e-47 159.3 0.3 1.0 1 0 0 1 1 1 1 Ferric uptake regulator family HTH_12 PF08461.10 EHU01500.1 - 0.0064 16.4 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain PadR PF03551.14 EHU01500.1 - 0.01 15.8 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family SR1P PF13790.6 EHU01500.1 - 0.013 15.5 3.7 0.7 10.1 0.3 2.5 2 0 0 2 2 2 0 SR1 protein DUF3399 PF11879.8 EHU01500.1 - 0.71 10.2 3.9 0.82 10.0 3.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3399) Flavodoxin_1 PF00258.25 EHU01501.1 - 1.3e-31 109.7 0.1 1.5e-31 109.5 0.1 1.0 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_3 PF12641.7 EHU01501.1 - 4.8e-11 42.6 0.0 5.7e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_5 PF12724.7 EHU01501.1 - 8e-07 29.4 0.0 1.2e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin domain FMN_red PF03358.15 EHU01501.1 - 0.054 13.2 0.0 0.64 9.8 0.0 2.6 1 1 0 1 1 1 0 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.7 EHU01501.1 - 0.058 13.1 0.1 0.16 11.7 0.0 1.6 1 1 1 2 2 2 0 Flavodoxin RHH_1 PF01402.21 EHU01502.1 - 1e-07 31.6 0.7 1.9e-07 30.7 0.7 1.5 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family Abhydrolase_1 PF00561.20 EHU01503.1 - 1.1e-21 77.6 0.2 7.2e-20 71.7 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EHU01503.1 - 3.1e-18 67.2 3.5 3.6e-18 67.0 3.5 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EHU01503.1 - 1.7e-11 44.3 0.0 3.7e-07 30.1 0.0 2.1 1 1 1 2 2 2 2 PGAP1-like protein Hydrolase_4 PF12146.8 EHU01503.1 - 3.9e-08 32.9 0.1 2.5e-06 26.9 0.1 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EHU01503.1 - 9.7e-06 25.9 0.0 1.2e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF676 PF05057.14 EHU01503.1 - 0.00024 20.7 0.1 0.00056 19.5 0.1 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.7 EHU01503.1 - 0.0018 18.1 0.1 0.004 16.9 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.11 EHU01503.1 - 0.0044 16.4 0.0 0.13 11.6 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 EHU01503.1 - 0.0075 15.9 0.0 0.0084 15.8 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 EHU01503.1 - 0.015 15.2 0.1 0.027 14.3 0.0 1.5 2 0 0 2 2 1 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 EHU01503.1 - 0.016 14.2 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.11 EHU01503.1 - 0.023 13.7 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase AXE1 PF05448.12 EHU01503.1 - 0.035 12.8 0.0 0.05 12.3 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Ndr PF03096.14 EHU01503.1 - 0.039 12.7 0.0 2.3 6.8 0.0 2.1 2 0 0 2 2 2 0 Ndr family DLH PF01738.18 EHU01503.1 - 0.061 12.9 0.0 0.16 11.5 0.0 1.7 2 1 0 2 2 2 0 Dienelactone hydrolase family Lipase_3 PF01764.25 EHU01503.1 - 0.069 13.0 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) LIDHydrolase PF10230.9 EHU01503.1 - 0.12 11.9 0.1 0.41 10.1 0.0 1.8 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase DUF2974 PF11187.8 EHU01503.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) BAAT_C PF08840.11 EHU01503.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF900 PF05990.12 EHU01503.1 - 0.15 11.5 0.1 0.27 10.7 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydro_lipase PF04083.16 EHU01503.1 - 0.18 11.4 0.0 0.38 10.4 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region DUF1057 PF06342.12 EHU01503.1 - 0.19 10.8 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) SeqA PF03925.13 EHU01504.1 - 9e-49 164.1 0.0 1.3e-48 163.5 0.0 1.3 1 0 0 1 1 1 1 SeqA protein C-terminal domain SeqA_N PF17206.3 EHU01504.1 - 4.1e-25 86.8 0.3 7.3e-25 86.0 0.3 1.4 1 0 0 1 1 1 1 SeqA protein N-terminal domain VAPB_antitox PF02697.14 EHU01504.1 - 0.15 12.8 0.0 0.32 11.8 0.0 1.6 1 1 0 1 1 1 0 Putative antitoxin PGM_PMM_I PF02878.16 EHU01505.1 - 1.2e-37 128.8 0.0 3e-37 127.4 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EHU01505.1 - 6.5e-30 103.7 0.0 1.4e-29 102.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EHU01505.1 - 9.1e-20 71.2 0.0 2.2e-19 70.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EHU01505.1 - 9e-09 35.4 0.0 2.3e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Response_reg PF00072.24 EHU01506.1 - 1.3e-26 92.9 0.0 2e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 EHU01506.1 - 7.9e-22 77.1 0.1 1.4e-21 76.3 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal DUF5064 PF16703.5 EHU01506.1 - 0.17 12.4 0.0 0.45 11.0 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5064) DUF2517 PF10725.9 EHU01507.1 - 1.6e-16 59.8 0.9 1.8e-16 59.7 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2517) CMD PF02627.20 EHU01508.1 - 1.2e-14 54.1 0.6 1.2e-14 54.1 0.6 1.8 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family DUF494 PF04361.13 EHU01508.1 - 0.004 17.1 0.0 0.0059 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF494) MarR_2 PF12802.7 EHU01509.1 - 1.8e-11 43.7 0.0 3.3e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 MarR family MarR PF01047.22 EHU01509.1 - 1.4e-09 37.7 0.0 2.9e-09 36.7 0.0 1.6 1 1 0 1 1 1 1 MarR family HTH_24 PF13412.6 EHU01509.1 - 0.00025 20.5 0.0 0.00084 18.9 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 EHU01509.1 - 0.0069 16.3 0.1 0.013 15.5 0.1 1.7 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_34 PF13601.6 EHU01509.1 - 0.031 14.4 0.0 0.051 13.8 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain DUF1722 PF08349.11 EHU01510.1 - 1.7e-42 144.4 0.6 3.8e-42 143.3 0.5 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1722) DUF523 PF04463.12 EHU01510.1 - 2.2e-39 134.6 0.0 3.1e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF523) RPAP2_Rtr1 PF04181.13 EHU01510.1 - 0.041 14.2 0.0 0.07 13.5 0.0 1.4 1 0 0 1 1 1 0 Rtr1/RPAP2 family RhoGAP PF00620.27 EHU01510.1 - 0.049 13.4 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 RhoGAP domain FAD_binding_7 PF03441.14 EHU01511.1 - 6.7e-83 277.1 5.5 1.2e-82 276.3 5.5 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EHU01511.1 - 1.1e-48 165.4 0.1 4.7e-48 163.3 0.1 1.9 2 0 0 2 2 2 1 DNA photolyase NIF3 PF01784.18 EHU01512.1 - 8.4e-57 192.6 0.0 1.2e-56 192.2 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Glyco_tran_10_N PF17039.5 EHU01512.1 - 0.15 12.5 0.0 0.22 12.0 0.0 1.2 1 0 0 1 1 1 0 Fucosyltransferase, N-terminal CT_C_D PF02682.16 EHU01513.1 - 1.3e-71 240.5 0.1 1.5e-71 240.3 0.1 1.0 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D CT_A_B PF02626.15 EHU01514.1 - 1.2e-93 313.6 0.0 1.4e-93 313.4 0.0 1.0 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B LamB_YcsF PF03746.16 EHU01515.1 - 1.5e-91 306.3 1.7 1.7e-91 306.2 1.7 1.0 1 0 0 1 1 1 1 LamB/YcsF family DUF969 PF06149.12 EHU01516.1 - 7.5e-88 293.6 3.2 8.6e-88 293.4 3.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF969) Na_H_antiport_2 PF13726.6 EHU01516.1 - 0.0068 16.5 2.1 0.013 15.6 2.1 1.5 1 0 0 1 1 1 1 Na+-H+ antiporter family PrgI PF12666.7 EHU01516.1 - 0.18 12.5 3.3 0.64 10.8 0.6 2.6 2 1 0 2 2 2 0 PrgI family protein DUF308 PF03729.13 EHU01516.1 - 9.7 6.6 13.3 1.4 9.3 7.7 2.4 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) DUF979 PF06166.12 EHU01517.1 - 5.6e-124 413.3 20.9 6.8e-124 413.1 20.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF979) Peptidase_C15 PF01470.17 EHU01518.1 - 3e-83 279.0 0.1 3.4e-83 278.8 0.1 1.0 1 0 0 1 1 1 1 Pyroglutamyl peptidase H2TH PF06831.14 EHU01519.1 - 1.4e-13 50.7 0.0 2.3e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.24 EHU01519.1 - 4.4e-10 40.2 0.0 8.4e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain zf-FPG_IleRS PF06827.14 EHU01519.1 - 2.1e-05 24.3 4.9 5.6e-05 22.9 4.9 1.8 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS DUF1778 PF08681.11 EHU01519.1 - 0.063 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1778) Acetyltransf_3 PF13302.7 EHU01520.1 - 1.9e-21 77.2 0.0 2.6e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CNP1 PF08750.11 EHU01520.1 - 0.0021 18.0 0.2 0.006 16.5 0.1 1.7 2 0 0 2 2 2 1 CNP1-like family Citrate_synt PF00285.21 EHU01521.1 - 4.4e-132 440.5 0.1 5.2e-132 440.3 0.1 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Sdh_cyt PF01127.22 EHU01522.1 - 5.7e-13 49.0 2.3 6.2e-13 48.8 2.3 1.0 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Fumarate_red_D PF02313.17 EHU01522.1 - 0.0073 16.4 1.3 0.0081 16.3 1.3 1.1 1 0 0 1 1 1 1 Fumarate reductase subunit D Sdh_cyt PF01127.22 EHU01523.1 - 4.2e-05 23.6 12.6 5e-05 23.3 12.6 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2070 PF09843.9 EHU01523.1 - 1.2 7.3 10.3 1.4 7.1 10.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) FAD_binding_2 PF00890.24 EHU01524.1 - 6.9e-119 397.6 5.7 8.7e-119 397.3 5.7 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EHU01524.1 - 7e-35 119.8 0.4 1.2e-34 119.1 0.4 1.4 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 EHU01524.1 - 6.6e-06 25.6 1.1 0.00037 19.8 0.3 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EHU01524.1 - 5.4e-05 22.4 3.2 0.0023 17.1 1.1 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.14 EHU01524.1 - 0.0039 16.0 3.6 0.0051 15.6 0.2 2.6 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.17 EHU01524.1 - 0.023 13.9 0.2 0.85 8.8 0.1 2.3 2 0 0 2 2 2 0 Thi4 family DAO PF01266.24 EHU01524.1 - 0.034 13.7 3.3 0.21 11.2 3.3 2.2 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EHU01524.1 - 1.6 8.0 8.1 3.1 7.1 5.0 2.6 2 1 0 2 2 2 0 FAD dependent oxidoreductase Fer2_3 PF13085.6 EHU01525.1 - 5.5e-32 110.0 0.0 7.8e-32 109.5 0.0 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 EHU01525.1 - 4.7e-10 39.9 1.5 8.4e-10 39.0 1.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EHU01525.1 - 3.5e-08 33.8 3.9 4.1e-07 30.3 4.5 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EHU01525.1 - 1.9e-07 31.1 1.9 3.7e-07 30.2 1.9 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 EHU01525.1 - 0.00062 20.3 6.3 0.0041 17.7 6.9 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EHU01525.1 - 0.0032 17.6 3.9 0.0032 17.6 3.9 2.2 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.6 EHU01525.1 - 0.0048 17.1 2.2 1.3 9.3 0.0 2.5 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4 PF00037.27 EHU01525.1 - 0.44 10.5 13.7 0.54 10.2 0.5 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 EHU01525.1 - 0.52 11.0 9.5 7.9 7.3 0.4 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.7 EHU01525.1 - 4 7.7 11.3 0.59 10.3 0.5 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Transket_pyr PF02779.24 EHU01526.1 - 1.2e-66 223.8 0.0 1.9e-66 223.1 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 EHU01526.1 - 3e-54 182.8 0.0 5.3e-54 182.0 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 EHU01526.1 - 1.2e-49 168.9 0.0 1.9e-49 168.3 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component 2-oxogl_dehyd_N PF16078.5 EHU01526.1 - 2.7e-16 58.9 0.4 1.6e-15 56.4 0.1 2.3 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus PFOR_II PF17147.4 EHU01526.1 - 0.0035 17.6 0.0 0.0094 16.2 0.0 1.7 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II 2-oxoacid_dh PF00198.23 EHU01527.1 - 1.2e-81 273.6 0.0 1.5e-81 273.3 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EHU01527.1 - 6.8e-19 67.5 0.4 1.5e-18 66.3 0.4 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EHU01527.1 - 5.7e-13 49.0 1.6 1.3e-12 47.9 0.1 2.2 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 EHU01527.1 - 0.0092 15.8 0.1 0.8 9.6 0.0 2.7 1 1 1 2 2 2 1 Biotin-lipoyl like GCV_H PF01597.19 EHU01527.1 - 0.15 12.0 0.7 1.3 8.9 0.2 2.4 2 0 0 2 2 2 0 Glycine cleavage H-protein ATP-grasp_2 PF08442.10 EHU01528.1 - 8.3e-83 276.9 0.0 1.2e-82 276.4 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 EHU01528.1 - 1.6e-23 83.2 2.8 2.7e-23 82.5 2.8 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 EHU01528.1 - 1.4e-14 54.1 0.0 2.5e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 EHU01528.1 - 0.0015 18.4 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp PF02222.22 EHU01528.1 - 0.049 13.2 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain CoA_binding PF02629.19 EHU01529.1 - 7.2e-30 103.5 0.6 7.2e-30 103.5 0.6 2.3 3 0 0 3 3 3 1 CoA binding domain Ligase_CoA PF00549.19 EHU01529.1 - 6.1e-20 71.6 1.6 9e-20 71.0 0.9 1.6 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.6 EHU01529.1 - 5.9e-11 42.3 0.1 1e-10 41.6 0.1 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EHU01529.1 - 0.00061 20.3 0.1 0.0024 18.3 0.0 2.0 2 1 1 3 3 3 1 CoA binding domain Lysine_decarbox PF03641.14 EHU01529.1 - 0.35 10.9 0.1 0.35 10.9 0.1 1.8 2 0 0 2 2 2 0 Possible lysine decarboxylase Cyt_bd_oxida_I PF01654.17 EHU01530.1 - 4.8e-175 582.2 22.4 5.5e-175 582.0 22.4 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit I Cyt_bd_oxida_II PF02322.15 EHU01531.1 - 7.7e-109 363.7 35.1 8.9e-109 363.5 35.1 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II YbgT_YccB PF08173.11 EHU01532.1 - 3.7e-14 52.5 6.6 4e-14 52.4 6.6 1.0 1 0 0 1 1 1 1 Membrane bound YbgT-like protein Cyd_oper_YbgE PF09600.10 EHU01533.1 - 1.3e-27 95.9 8.3 1.5e-27 95.7 8.3 1.0 1 0 0 1 1 1 1 Cyd operon protein YbgE (Cyd_oper_YbgE) 4HBT PF03061.22 EHU01534.1 - 7.9e-19 67.8 0.3 1.1e-18 67.3 0.3 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 EHU01534.1 - 1.5e-10 41.6 0.2 1.6e-10 41.5 0.2 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 EHU01534.1 - 3.7e-05 23.2 0.1 4.1e-05 23.0 0.1 1.1 1 0 0 1 1 1 1 Acyl-ACP thioesterase MotA_ExbB PF01618.16 EHU01535.1 - 2.2e-41 140.6 0.7 3e-41 140.1 0.7 1.2 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family ExbD PF02472.16 EHU01536.1 - 3.4e-24 85.5 0.1 3.8e-24 85.3 0.1 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR TolA PF06519.11 EHU01537.1 - 1e-36 125.0 0.1 1e-36 125.0 0.1 3.2 3 1 0 3 3 3 1 TolA C-terminal PD40 PF07676.12 EHU01538.1 - 1.7e-35 120.2 4.3 7.9e-10 38.4 0.3 6.0 6 0 0 6 6 6 4 WD40-like Beta Propeller Repeat TolB_N PF04052.13 EHU01538.1 - 1.4e-33 115.2 0.1 4.9e-33 113.5 0.0 2.0 2 0 0 2 2 2 1 TolB amino-terminal domain DPPIV_N PF00930.21 EHU01538.1 - 2.2e-11 43.1 0.0 7.4e-08 31.5 0.0 3.0 1 1 2 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Pectate_lyase22 PF14583.6 EHU01538.1 - 1.2e-07 30.7 0.2 0.0015 17.3 0.1 3.6 2 1 2 4 4 4 3 Oligogalacturonate lyase Gmad1 PF10647.9 EHU01538.1 - 5e-06 26.4 2.1 0.019 14.7 0.5 3.7 2 1 1 3 3 3 2 Lipoprotein LpqB beta-propeller domain Peptidase_S9_N PF02897.15 EHU01538.1 - 6.9e-05 21.8 0.0 0.00045 19.1 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase, N-terminal beta-propeller domain PilZ_2 PF16823.5 EHU01538.1 - 0.033 14.3 0.1 0.073 13.2 0.1 1.5 1 0 0 1 1 1 0 Atypical PilZ domain, cyclic di-GMP receptor OmpA PF00691.20 EHU01539.1 - 1.3e-22 79.9 0.0 2.2e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 OmpA family TolA_bind_tri PF16331.5 EHU01540.1 - 7.5e-24 83.6 15.8 1.5e-23 82.7 15.8 1.5 1 0 0 1 1 1 1 TolA binding protein trimerisation TPR_6 PF13174.6 EHU01540.1 - 2e-18 65.7 13.2 3.5e-07 30.4 0.0 4.0 5 0 0 5 5 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 EHU01540.1 - 1.6e-16 60.7 3.9 1.1e-08 35.5 0.2 3.9 1 1 2 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EHU01540.1 - 3.6e-13 48.5 3.2 0.00012 22.0 0.0 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EHU01540.1 - 1.1e-09 38.3 0.2 0.039 14.8 0.0 3.8 2 1 1 3 3 3 3 Tetratricopeptide repeat YfiO PF13525.6 EHU01540.1 - 2.9e-09 36.9 8.1 1.1e-08 35.1 8.1 1.9 1 1 0 1 1 1 1 Outer membrane lipoprotein TPR_8 PF13181.6 EHU01540.1 - 5e-08 32.5 7.1 0.0021 18.1 0.0 4.3 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EHU01540.1 - 3.7e-07 29.7 4.7 0.04 13.7 0.8 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EHU01540.1 - 4.8e-07 30.0 0.3 8.5e-05 22.8 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EHU01540.1 - 3.8e-05 24.1 14.7 0.00065 20.2 1.5 3.4 2 1 2 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EHU01540.1 - 4.2e-05 23.7 6.0 0.00016 21.8 1.5 3.1 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_18 PF13512.6 EHU01540.1 - 6.3e-05 23.1 6.9 0.04 14.0 6.9 2.6 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 EHU01540.1 - 0.00098 19.3 5.4 0.82 10.2 0.5 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat HrpB7 PF09486.10 EHU01540.1 - 0.0029 18.0 2.7 0.0029 18.0 2.7 1.6 1 1 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) DUF4810 PF16068.5 EHU01540.1 - 0.0032 18.0 7.8 0.62 10.6 0.1 4.4 2 2 2 4 4 4 1 Domain of unknown function (DUF4810) Allexi_40kDa PF05549.11 EHU01540.1 - 0.0033 17.0 0.6 0.0051 16.4 0.6 1.2 1 0 0 1 1 1 1 Allexivirus 40kDa protein Spc29 PF17082.5 EHU01540.1 - 0.0043 16.9 0.3 0.0058 16.5 0.3 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 FlgM PF04316.13 EHU01540.1 - 0.0081 16.5 1.1 0.038 14.4 0.8 2.3 1 1 0 1 1 1 1 Anti-sigma-28 factor, FlgM V_ATPase_I PF01496.19 EHU01540.1 - 0.038 11.9 0.3 0.06 11.3 0.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF406 PF04175.12 EHU01540.1 - 0.046 14.2 1.0 1.5 9.4 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF406) TPR_11 PF13414.6 EHU01540.1 - 0.076 12.7 17.1 0.47 10.2 4.2 4.5 4 2 1 5 5 3 0 TPR repeat SlyX PF04102.12 EHU01540.1 - 0.076 13.6 12.2 0.54 10.9 12.2 2.4 1 1 0 1 1 1 0 SlyX FAM76 PF16046.5 EHU01540.1 - 0.08 12.3 0.4 0.13 11.6 0.4 1.3 1 0 0 1 1 1 0 FAM76 protein Prominin PF05478.11 EHU01540.1 - 0.089 10.7 1.2 0.12 10.3 1.2 1.1 1 0 0 1 1 1 0 Prominin IFT57 PF10498.9 EHU01540.1 - 0.12 11.3 5.4 0.2 10.6 5.4 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 COG2 PF06148.11 EHU01540.1 - 0.41 10.7 4.7 0.41 10.7 2.0 2.0 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 EHU01540.1 - 0.6 10.2 4.7 1.3 9.1 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 EHU01540.1 - 0.8 10.0 4.2 0.8 10.0 1.2 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) GRDP-like PF07173.12 EHU01540.1 - 1 10.0 6.1 0.48 11.1 1.4 2.2 2 1 0 2 2 2 0 Glycine-rich domain-containing protein-like Rootletin PF15035.6 EHU01540.1 - 2.4 8.2 10.9 3.9 7.5 10.8 1.7 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Seryl_tRNA_N PF02403.22 EHU01540.1 - 5.2 7.3 9.3 2 8.7 3.4 2.6 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF3693 PF12472.8 EHU01540.1 - 5.6 6.7 7.5 40 4.0 0.0 3.3 3 0 0 3 3 3 0 Phage related protein HemX PF04375.14 EHU01540.1 - 6 6.1 20.6 0.25 10.6 9.2 2.5 3 0 0 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase TPR_3 PF07720.12 EHU01540.1 - 6.6 6.8 12.9 5.1 7.2 0.5 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat AlkA_N PF06029.11 EHU01541.1 - 7.8e-39 132.5 1.1 3.7e-38 130.4 0.3 2.3 2 0 0 2 2 2 1 AlkA N-terminal domain Ada_Zn_binding PF02805.16 EHU01541.1 - 4.6e-29 100.2 3.7 8.4e-29 99.4 3.7 1.5 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_18 PF12833.7 EHU01541.1 - 2.7e-22 78.8 0.9 6.2e-22 77.7 0.3 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 EHU01541.1 - 8.7e-12 44.8 0.0 0.00029 20.9 0.0 3.2 3 0 0 3 3 3 2 Bacterial regulatory helix-turn-helix proteins, AraC family HhH-GPD PF00730.25 EHU01541.1 - 6.5e-09 36.2 0.0 2.1e-08 34.6 0.0 1.8 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein GntR PF00392.21 EHU01541.1 - 5.6e-05 22.7 4.4 0.0072 15.9 0.2 3.4 3 0 0 3 3 3 1 Bacterial regulatory proteins, gntR family HTH_28 PF13518.6 EHU01541.1 - 0.0067 16.5 0.0 0.027 14.6 0.0 2.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 EHU01541.1 - 0.0073 16.1 0.1 0.06 13.2 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain MHYT PF03707.16 EHU01541.1 - 0.059 13.5 0.1 0.18 12.0 0.0 1.9 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat Integrase_Zn PF02022.19 EHU01541.1 - 0.11 12.5 0.1 0.45 10.5 0.1 2.1 2 0 0 2 2 2 0 Integrase Zinc binding domain DNA_binding_1 PF01035.20 EHU01542.1 - 4.3e-31 106.9 0.0 6.3e-31 106.3 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_1N PF02870.15 EHU01542.1 - 7.7e-10 39.4 0.0 1.1e-09 38.9 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain NadA PF02445.16 EHU01543.1 - 1.5e-101 339.5 0.1 1.8e-101 339.3 0.1 1.0 1 0 0 1 1 1 1 Quinolinate synthetase A protein NMN_transporter PF04973.12 EHU01544.1 - 3.2e-48 164.0 30.6 4.9e-48 163.4 30.6 1.3 1 0 0 1 1 1 1 Nicotinamide mononucleotide transporter LapA_dom PF06305.11 EHU01544.1 - 3.4 7.6 10.1 1.8 8.4 0.1 3.1 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Cation_efflux PF01545.21 EHU01545.1 - 3.3e-51 173.9 15.9 3.9e-51 173.6 15.9 1.1 1 0 0 1 1 1 1 Cation efflux family 7tm_3 PF00003.22 EHU01545.1 - 0.048 13.4 2.6 3.2 7.4 0.1 2.2 1 1 1 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR Vut_1 PF02592.15 EHU01545.1 - 0.21 11.9 8.4 0.04 14.2 3.7 1.8 2 0 0 2 2 2 0 Putative vitamin uptake transporter SBP_bac_3 PF00497.20 EHU01546.1 - 1.6e-38 132.4 0.0 2e-23 83.0 0.0 2.5 2 0 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 HATPase_c PF02518.26 EHU01546.1 - 5.1e-30 104.3 0.0 1e-29 103.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EHU01546.1 - 1.7e-14 53.6 5.0 7e-14 51.6 2.4 2.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 EHU01546.1 - 4.1e-10 39.8 0.1 1.2e-09 38.3 0.1 1.9 1 0 0 1 1 1 1 Response regulator receiver domain Hpt PF01627.23 EHU01546.1 - 6.4e-08 32.7 2.0 6.4e-08 32.7 2.0 2.9 2 0 0 2 2 2 1 Hpt domain HATPase_c_2 PF13581.6 EHU01546.1 - 8.2e-05 22.6 0.0 0.00021 21.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain KIP1 PF07765.12 EHU01546.1 - 0.021 15.0 0.4 0.055 13.6 0.4 1.7 1 0 0 1 1 1 0 KIP1-like protein Miga PF10265.9 EHU01546.1 - 0.13 11.2 0.1 0.21 10.5 0.1 1.2 1 0 0 1 1 1 0 Mitoguardin HATPase_c_3 PF13589.6 EHU01546.1 - 0.23 11.3 0.0 0.48 10.2 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GerE PF00196.19 EHU01547.1 - 2.2e-20 72.0 1.1 2.6e-20 71.7 0.3 1.5 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family Response_reg PF00072.24 EHU01547.1 - 6.3e-19 68.2 0.0 1.5e-18 67.0 0.0 1.6 2 0 0 2 2 2 1 Response regulator receiver domain Sigma70_r4_2 PF08281.12 EHU01547.1 - 2.5e-05 23.9 0.1 6.8e-05 22.5 0.1 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 EHU01547.1 - 0.00034 20.3 0.3 0.001 18.8 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_24 PF13412.6 EHU01547.1 - 0.00072 19.1 0.3 0.0031 17.1 0.2 2.2 1 1 1 2 2 2 1 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 EHU01547.1 - 0.0012 18.4 0.0 0.0053 16.2 0.1 2.1 2 1 0 2 2 2 1 Sigma-70, region 4 HTH_29 PF13551.6 EHU01547.1 - 0.003 17.6 0.0 0.08 13.0 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn helix HTH_38 PF13936.6 EHU01547.1 - 0.027 14.2 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_20 PF12840.7 EHU01547.1 - 0.041 14.0 0.1 0.13 12.3 0.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 EHU01547.1 - 0.045 13.2 0.1 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_7 PF02796.15 EHU01547.1 - 0.049 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 EHU01547.1 - 0.095 12.8 0.1 0.53 10.5 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_11 PF08279.12 EHU01547.1 - 0.12 12.4 0.3 0.28 11.2 0.3 1.7 1 0 0 1 1 1 0 HTH domain HTH_5 PF01022.20 EHU01547.1 - 0.12 12.3 0.6 0.32 10.9 0.5 1.8 1 1 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_10 PF04967.12 EHU01547.1 - 3.9 7.4 5.0 1.8 8.4 0.1 2.6 3 0 0 3 3 3 0 HTH DNA binding domain YbgS PF13985.6 EHU01548.1 - 1.3e-52 177.2 15.6 1.4e-52 177.0 15.6 1.0 1 0 0 1 1 1 1 YbgS-like protein PepSY_2 PF13670.6 EHU01548.1 - 3.4 7.7 5.2 17 5.5 5.2 2.1 1 1 1 2 2 2 0 Peptidase propeptide and YPEB domain DDE_Tnp_IS66 PF03050.14 EHU01549.1 - 1.1e-97 326.9 4.0 3.8e-97 325.1 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU01549.1 - 3.2e-16 59.2 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU01549.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU01549.1 - 1.2e-11 45.2 9.0 2.6e-11 44.1 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHU01549.1 - 0.017 14.9 6.4 0.027 14.3 6.4 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Phage_HK97_TLTM PF06120.11 EHU01549.1 - 0.022 14.0 1.7 0.042 13.0 1.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHU01549.1 - 0.022 15.1 4.3 0.091 13.1 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain FUSC PF04632.12 EHU01549.1 - 0.038 12.6 6.8 0.06 11.9 6.8 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 EHU01549.1 - 0.04 13.5 2.2 0.047 13.2 0.8 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Tho2 PF11262.8 EHU01549.1 - 0.057 12.6 0.5 0.094 11.9 0.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Troponin PF00992.20 EHU01549.1 - 0.062 13.6 3.0 0.11 12.8 3.0 1.3 1 0 0 1 1 1 0 Troponin LXG PF04740.12 EHU01549.1 - 0.11 12.3 2.5 0.32 10.7 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily UME PF08064.13 EHU01549.1 - 0.15 12.0 0.5 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain ERM PF00769.19 EHU01549.1 - 0.16 11.8 10.8 0.26 11.1 10.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HalX PF08663.10 EHU01549.1 - 0.23 11.8 3.1 0.59 10.5 3.1 1.7 1 0 0 1 1 1 0 HalX domain DHR10 PF18595.1 EHU01549.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Zn-ribbon_8 PF09723.10 EHU01549.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF1192 PF06698.11 EHU01549.1 - 0.53 10.4 5.3 3.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHU01549.1 - 1.1 8.4 3.1 1.7 7.8 3.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHU01549.1 - 2.8 7.4 7.9 6.1 6.3 7.9 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHU01549.1 - 3.3 8.1 7.9 6.7 7.0 7.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 EHU01549.1 - 7.2 7.3 8.7 7.7 7.2 1.0 3.0 1 1 1 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHU01550.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHU01551.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU01551.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU01551.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU01551.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHU01552.1 - 1e-34 118.5 0.0 1.1e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHU01553.1 - 2.8e-99 332.1 3.5 1.6e-98 329.7 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU01553.1 - 3.1e-16 59.3 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU01553.1 - 8e-15 55.0 1.3 1.9e-14 53.8 1.3 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU01553.1 - 1.7e-11 44.7 9.6 3.5e-11 43.7 9.6 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHU01553.1 - 0.017 14.9 6.4 0.027 14.3 6.4 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Phage_HK97_TLTM PF06120.11 EHU01553.1 - 0.021 14.0 1.7 0.042 13.0 1.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHU01553.1 - 0.022 15.1 4.3 0.091 13.1 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Exonuc_VII_L PF02601.15 EHU01553.1 - 0.028 14.0 1.8 0.039 13.5 0.6 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit FUSC PF04632.12 EHU01553.1 - 0.03 12.9 6.9 0.056 12.0 6.9 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tho2 PF11262.8 EHU01553.1 - 0.057 12.6 0.5 0.094 11.9 0.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Troponin PF00992.20 EHU01553.1 - 0.062 13.6 3.0 0.11 12.8 3.0 1.3 1 0 0 1 1 1 0 Troponin LXG PF04740.12 EHU01553.1 - 0.11 12.2 2.6 0.33 10.6 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHU01553.1 - 0.16 11.8 10.8 0.26 11.1 10.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family UME PF08064.13 EHU01553.1 - 0.16 11.9 0.5 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain HalX PF08663.10 EHU01553.1 - 0.23 11.8 3.1 0.59 10.5 3.1 1.7 1 0 0 1 1 1 0 HalX domain DHR10 PF18595.1 EHU01553.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF1192 PF06698.11 EHU01553.1 - 0.47 10.5 5.3 3.4 7.8 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHU01553.1 - 1.1 8.4 3.1 1.7 7.8 3.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHU01553.1 - 2.8 7.4 7.9 6.1 6.3 7.9 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHU01553.1 - 3.2 8.1 7.9 6.7 7.0 7.9 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 EHU01553.1 - 7.1 7.3 8.7 7.7 7.2 1.0 3.1 1 1 1 2 2 2 0 SlyX SLT PF01464.20 EHU01557.1 - 8.5e-24 83.5 0.1 2.5e-23 82.0 0.1 1.8 1 0 0 1 1 1 1 Transglycosylase SLT domain PhageMin_Tail PF10145.9 EHU01557.1 - 0.00035 20.5 2.5 0.00035 20.5 2.5 3.5 2 1 1 3 3 3 1 Phage-related minor tail protein Transglycosylas PF06737.14 EHU01557.1 - 0.0065 17.1 0.1 0.023 15.3 0.1 1.9 1 0 0 1 1 1 1 Transglycosylase-like domain UBA_4 PF14555.6 EHU01557.1 - 0.025 14.4 2.3 0.29 11.0 0.0 3.6 4 0 0 4 4 4 0 UBA-like domain Umbravirus_LDM PF04817.12 EHU01559.1 - 0.024 14.0 0.0 0.031 13.6 0.0 1.1 1 0 0 1 1 1 0 Umbravirus long distance movement (LDM) family DUF3277 PF11681.8 EHU01560.1 - 1.4e-70 235.8 2.2 1.5e-70 235.7 2.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3277) DUF3383 PF11863.8 EHU01561.1 - 8.1e-181 602.2 19.1 9.1e-181 602.0 19.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3383) DUF4072 PF13284.6 EHU01561.1 - 9.2 6.8 10.3 21 5.7 0.9 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4072) DDE_3 PF13358.6 EHU01565.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHU01565.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHU01565.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHU01565.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHU01565.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHU01565.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHU01565.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHU01565.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 PilJ PF13675.6 EHU01566.1 - 1.4e-19 70.2 3.4 1.4e-19 70.2 3.4 3.4 3 1 1 4 4 4 1 Type IV pili methyl-accepting chemotaxis transducer N-term HisKA_3 PF07730.13 EHU01566.1 - 1.4e-14 54.4 6.4 1.4e-14 54.4 6.4 3.9 4 0 0 4 4 4 1 Histidine kinase HAMP PF00672.25 EHU01566.1 - 0.00063 20.1 0.0 0.0031 17.9 0.0 2.3 2 0 0 2 2 2 1 HAMP domain HATPase_c PF02518.26 EHU01566.1 - 0.0012 19.3 0.3 0.004 17.6 0.1 2.0 2 1 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EHU01566.1 - 0.0016 18.4 0.0 0.004 17.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 EHU01566.1 - 0.014 15.2 0.1 0.033 14.0 0.1 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ESCRT-II PF05871.12 EHU01566.1 - 0.12 12.6 0.4 0.29 11.4 0.4 1.8 1 0 0 1 1 1 0 ESCRT-II complex subunit Nbl1_Borealin_N PF10444.9 EHU01566.1 - 0.13 11.9 1.3 0.51 10.0 0.5 2.5 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal Lipase_2 PF01674.18 EHU01566.1 - 0.18 11.3 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 2) DDE_Tnp_ISL3 PF01610.17 EHU01566.1 - 0.83 9.3 5.8 0.48 10.1 2.0 2.3 2 0 0 2 2 2 0 Transposase CorA PF01544.18 EHU01566.1 - 1.2 8.4 8.5 0.48 9.7 4.6 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 EHU01566.1 - 4 7.5 9.4 2.4 8.2 1.5 3.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.11 EHU01566.1 - 4.9 5.0 8.0 1.4 6.8 0.0 2.8 3 0 0 3 3 3 0 Prominin DUF1471 PF07338.13 EHU01567.1 - 2.6e-18 65.7 0.0 3.9e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1471) AA_permease PF00324.21 EHU01568.1 - 3.6e-125 418.3 41.8 4.4e-125 418.0 41.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EHU01568.1 - 1.1e-42 146.4 43.7 1.4e-42 146.1 43.7 1.0 1 0 0 1 1 1 1 Amino acid permease Phage_holin_2_4 PF16082.5 EHU01568.1 - 0.22 11.2 3.3 1.4 8.7 0.1 3.4 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like NUDIX PF00293.28 EHU01569.1 - 1.6e-09 37.9 0.0 2e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain ROK PF00480.20 EHU01570.1 - 3.6e-48 164.5 0.0 4.1e-48 164.4 0.0 1.0 1 0 0 1 1 1 1 ROK family Glucokinase PF02685.16 EHU01570.1 - 6.4e-05 22.1 1.6 0.0033 16.5 1.6 2.6 2 1 0 2 2 2 1 Glucokinase BcrAD_BadFG PF01869.20 EHU01570.1 - 0.074 12.5 0.0 0.17 11.3 0.0 1.6 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Ribul_P_3_epim PF00834.19 EHU01571.1 - 2.2e-61 206.7 0.2 2.6e-61 206.5 0.2 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family BPD_transp_2 PF02653.16 EHU01572.1 - 1.6e-26 93.1 46.9 2.2e-26 92.6 46.9 1.2 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component DUF4516 PF14990.6 EHU01572.1 - 0.023 14.4 0.3 0.023 14.4 0.3 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4516) BPD_transp_2 PF02653.16 EHU01573.1 - 1.2e-35 123.1 41.7 1.8e-35 122.4 41.7 1.3 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component ECSCR PF15820.5 EHU01573.1 - 3.2 7.6 4.8 36 4.3 0.2 2.7 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator LapA_dom PF06305.11 EHU01573.1 - 4.5 7.2 19.0 0.2 11.5 2.9 4.4 4 1 0 4 4 4 0 Lipopolysaccharide assembly protein A domain ABC_tran PF00005.27 EHU01574.1 - 4.6e-50 169.7 0.0 1.5e-25 90.3 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EHU01574.1 - 8e-06 25.9 2.3 0.017 14.9 0.0 3.1 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EHU01574.1 - 0.0021 17.6 0.0 0.57 9.6 0.0 2.7 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EHU01574.1 - 0.0069 16.3 0.7 0.018 15.0 0.1 2.0 2 1 1 3 3 3 1 RsgA GTPase AAA_29 PF13555.6 EHU01574.1 - 0.0097 15.6 0.1 0.048 13.4 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.29 EHU01574.1 - 0.011 16.1 0.9 2.9 8.3 0.0 3.1 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EHU01574.1 - 0.012 15.6 0.2 0.16 11.9 0.0 2.6 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_25 PF13481.6 EHU01574.1 - 0.013 15.1 0.5 0.5 9.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 EHU01574.1 - 0.016 15.7 0.2 1.2 9.7 0.1 2.9 3 0 0 3 3 3 0 AAA domain ATPase_2 PF01637.18 EHU01574.1 - 0.019 14.9 0.2 14 5.5 0.0 3.0 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_15 PF13175.6 EHU01574.1 - 0.031 14.0 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 EHU01574.1 - 0.067 12.9 0.3 2.2 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EHU01574.1 - 0.12 12.3 0.3 9.3 6.3 0.1 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 EHU01574.1 - 0.2 10.9 0.4 0.95 8.7 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.6 EHU01574.1 - 0.23 12.0 0.1 0.54 10.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EHU01574.1 - 5.6 7.2 7.0 47 4.3 0.4 3.6 4 0 0 4 4 4 0 AAA domain Peripla_BP_4 PF13407.6 EHU01575.1 - 5.1e-49 167.2 0.4 6.1e-49 166.9 0.4 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 EHU01575.1 - 0.00011 21.7 0.0 0.00017 21.1 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family DeoRC PF00455.22 EHU01576.1 - 3.7e-44 150.5 0.0 5.1e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 EHU01576.1 - 3e-16 58.9 1.1 7e-16 57.7 0.6 1.9 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain MarR_2 PF12802.7 EHU01576.1 - 9e-05 22.3 1.1 0.0003 20.6 0.3 2.1 2 0 0 2 2 2 1 MarR family GntR PF00392.21 EHU01576.1 - 0.00013 21.5 0.2 0.00031 20.3 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HxlR PF01638.17 EHU01576.1 - 0.00026 20.8 0.5 0.026 14.3 0.1 2.6 3 0 0 3 3 2 1 HxlR-like helix-turn-helix MarR PF01047.22 EHU01576.1 - 0.0031 17.4 0.5 0.0093 15.9 0.2 1.9 2 0 0 2 2 2 1 MarR family HTH_11 PF08279.12 EHU01576.1 - 0.0033 17.3 0.2 0.0083 16.1 0.2 1.7 1 0 0 1 1 1 1 HTH domain HTH_20 PF12840.7 EHU01576.1 - 0.0036 17.3 0.8 0.0073 16.3 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 EHU01576.1 - 0.023 14.6 0.1 0.069 13.1 0.1 1.8 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_5 PF01022.20 EHU01576.1 - 0.048 13.5 0.1 0.1 12.5 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 EHU01576.1 - 0.054 13.1 0.9 0.15 11.7 0.9 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_36 PF13730.6 EHU01576.1 - 0.057 13.4 0.1 0.14 12.1 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Penicillinase_R PF03965.16 EHU01576.1 - 0.1 12.9 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Penicillinase repressor DUF1176 PF06674.11 EHU01577.1 - 1.5e-91 307.2 0.0 1.7e-91 307.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1176) Beta-lactamase PF00144.24 EHU01578.1 - 4.9e-65 219.9 0.4 6.2e-65 219.6 0.4 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 EHU01578.1 - 0.0056 16.1 0.0 0.016 14.7 0.0 1.7 2 0 0 2 2 2 1 D-alanyl-D-alanine carboxypeptidase Response_reg PF00072.24 EHU01579.1 - 7.1e-17 61.6 0.0 2.9e-16 59.6 0.0 1.9 1 1 1 2 2 2 1 Response regulator receiver domain HTH_IclR PF09339.10 EHU01579.1 - 4.6e-05 23.1 0.8 9.2e-05 22.2 0.1 1.9 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_DeoR PF08220.12 EHU01579.1 - 0.045 13.5 0.0 0.087 12.6 0.0 1.4 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_24 PF13412.6 EHU01579.1 - 0.06 12.9 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_40 PF14493.6 EHU01579.1 - 0.16 12.4 0.0 0.37 11.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain sCache_3_2 PF17203.4 EHU01580.1 - 1.4e-17 64.1 0.4 2.9e-17 63.1 0.4 1.4 1 0 0 1 1 1 1 Single cache domain 3 HATPase_c PF02518.26 EHU01580.1 - 1.6e-15 57.6 0.0 3.4e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 EHU01580.1 - 3e-09 36.7 0.0 8.2e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 GHKL domain SPOB_a PF14689.6 EHU01580.1 - 1.4e-07 31.1 1.1 3.6e-07 29.8 1.1 1.6 1 0 0 1 1 1 1 Sensor_kinase_SpoOB-type, alpha-helical domain PAS PF00989.25 EHU01580.1 - 0.00013 21.9 0.0 0.00031 20.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold HATPase_c_2 PF13581.6 EHU01580.1 - 0.00028 20.9 0.0 0.00064 19.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PAS_8 PF13188.7 EHU01580.1 - 0.00029 20.8 0.0 0.00065 19.7 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 EHU01580.1 - 0.0008 19.6 0.0 0.0029 17.8 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS_7 PF12860.7 EHU01580.1 - 0.0059 16.7 0.0 0.024 14.8 0.0 2.1 1 1 1 2 2 2 1 PAS fold PAS_4 PF08448.10 EHU01580.1 - 0.008 16.4 0.0 0.33 11.2 0.0 2.4 2 0 0 2 2 2 1 PAS fold AAA_lid_10 PF17872.1 EHU01580.1 - 0.19 11.9 0.4 1.3 9.2 0.0 2.3 3 0 0 3 3 3 0 AAA lid domain RcnB PF11776.8 EHU01581.1 - 1.3e-21 76.4 0.7 2.1e-21 75.7 0.7 1.4 1 0 0 1 1 1 1 Nickel/cobalt transporter regulator 2HCT PF03390.15 EHU01581.1 - 1.7e-19 69.8 0.8 2.4e-19 69.3 0.8 1.2 1 0 0 1 1 1 1 2-hydroxycarboxylate transporter family Hydrolase_3 PF08282.12 EHU01582.1 - 1.5e-27 97.0 0.0 1.7e-27 96.8 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EHU01582.1 - 7.6e-05 22.3 0.0 0.0076 15.8 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase MULE PF10551.9 EHU01582.1 - 0.024 15.1 0.0 0.056 13.9 0.0 1.7 1 1 0 1 1 1 0 MULE transposase domain Hydrolase_3 PF08282.12 EHU01583.1 - 3.6e-17 63.0 0.0 4e-17 62.8 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EHU01583.1 - 0.093 12.2 0.0 0.12 11.9 0.0 1.2 1 1 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase Fe-ADH PF00465.19 EHU01584.1 - 4.2e-73 246.3 0.2 5e-73 246.0 0.2 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EHU01584.1 - 2.4e-13 50.4 0.0 3.7e-06 26.8 0.1 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase GntP_permease PF02447.16 EHU01585.1 - 5.6e-181 602.0 40.3 6.5e-181 601.8 40.3 1.0 1 0 0 1 1 1 1 GntP family permease CitMHS PF03600.16 EHU01585.1 - 2.8e-26 92.4 41.2 3.7e-26 92.0 41.2 1.1 1 0 0 1 1 1 1 Citrate transporter Na_H_antiport_2 PF13726.6 EHU01585.1 - 9.6 6.4 27.0 0.67 10.1 9.4 3.6 3 0 0 3 3 3 0 Na+-H+ antiporter family PagP PF07017.11 EHU01587.1 - 7.7e-66 220.0 5.5 9.2e-66 219.7 5.5 1.1 1 0 0 1 1 1 1 Antimicrobial peptide resistance and lipid A acylation protein PagP CSD PF00313.22 EHU01588.1 - 1.3e-33 114.7 0.5 1.4e-33 114.6 0.5 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 EHU01588.1 - 1.9e-05 24.3 0.4 3.7e-05 23.3 0.4 1.6 1 1 0 1 1 1 1 Ribonuclease B OB domain CusF_Ec PF11604.8 EHU01588.1 - 0.098 12.6 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Copper binding periplasmic protein CusF S1 PF00575.23 EHU01588.1 - 0.11 12.8 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 S1 RNA binding domain CN_hydrolase PF00795.22 EHU01589.1 - 8e-41 140.1 0.1 8.9e-41 139.9 0.1 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MttA_Hcf106 PF02416.16 EHU01590.1 - 3.9e-13 48.5 0.1 4.3e-13 48.4 0.1 1.1 1 0 0 1 1 1 1 mttA/Hcf106 family Radical_SAM PF04055.21 EHU01591.1 - 5.3e-15 56.2 0.0 9.9e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily LIAS_N PF16881.5 EHU01591.1 - 2.3e-07 31.2 0.0 1.5e-06 28.6 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family BPL_LplA_LipB PF03099.19 EHU01592.1 - 3.5e-06 27.0 0.0 8.2e-06 25.8 0.0 1.6 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF493 PF04359.14 EHU01593.1 - 5.5e-29 100.6 0.0 6.1e-29 100.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF493) MBG_2 PF18676.1 EHU01593.1 - 0.078 13.6 0.0 0.1 13.3 0.0 1.2 1 0 0 1 1 1 0 MBG domain (YGX type) Peptidase_S11 PF00768.20 EHU01594.1 - 3e-101 337.9 0.2 3.8e-101 337.5 0.2 1.1 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase PBP5_C PF07943.13 EHU01594.1 - 6.5e-26 90.4 0.0 1.2e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 Penicillin-binding protein 5, C-terminal domain Beta-lactamase2 PF13354.6 EHU01594.1 - 4.2e-09 36.3 0.0 5.9e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase enzyme family Beta-lactamase PF00144.24 EHU01594.1 - 0.0041 16.4 0.4 0.031 13.5 0.1 2.0 1 1 0 2 2 2 1 Beta-lactamase DPBB_1 PF03330.18 EHU01595.1 - 9.9e-24 83.4 0.0 1.8e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Lytic transglycolase SPOR PF05036.13 EHU01595.1 - 8.7e-16 58.1 2.5 1.8e-15 57.1 2.5 1.5 1 0 0 1 1 1 1 Sporulation related domain FTSW_RODA_SPOVE PF01098.19 EHU01596.1 - 1.6e-124 415.5 26.6 2e-124 415.3 26.6 1.0 1 0 0 1 1 1 1 Cell cycle protein Transpeptidase PF00905.22 EHU01597.1 - 1.7e-88 296.7 0.0 3.6e-88 295.7 0.0 1.5 2 0 0 2 2 2 1 Penicillin binding protein transpeptidase domain PBP_dimer PF03717.15 EHU01597.1 - 3e-44 151.5 0.2 4.7e-44 150.9 0.2 1.3 1 0 0 1 1 1 1 Penicillin-binding Protein dimerisation domain ANAPC_CDC26 PF10471.9 EHU01597.1 - 0.14 13.0 0.2 0.31 11.9 0.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 SPOUT_MTase PF02590.17 EHU01598.1 - 2.4e-47 160.8 0.0 2.7e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 Predicted SPOUT methyltransferase RsfS PF02410.15 EHU01599.1 - 2.6e-29 101.6 0.2 2.9e-29 101.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation CTP_transf_like PF01467.26 EHU01600.1 - 8.3e-32 110.3 0.0 9.8e-32 110.1 0.0 1.0 1 0 0 1 1 1 1 Cytidylyltransferase-like DNA_pol3_delt_C PF14840.6 EHU01601.1 - 1.4e-50 170.8 9.3 1.4e-50 170.8 9.3 1.8 2 0 0 2 2 2 1 Processivity clamp loader gamma complex DNA pol III C-term DNA_pol3_delta PF06144.13 EHU01601.1 - 1.1e-44 152.3 0.2 3e-44 150.9 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase III, delta subunit Med11 PF10280.9 EHU01601.1 - 0.14 12.6 4.0 0.25 11.8 4.0 1.4 1 0 0 1 1 1 0 Mediator complex protein LptE PF04390.12 EHU01602.1 - 4e-13 50.0 0.8 5.2e-13 49.6 0.8 1.1 1 0 0 1 1 1 1 Lipopolysaccharide-assembly NEMP PF10225.9 EHU01602.1 - 0.075 12.7 0.2 0.14 11.8 0.2 1.3 1 0 0 1 1 1 0 NEMP family tRNA-synt_1_2 PF13603.6 EHU01603.1 - 1.2e-76 256.3 0.0 2e-76 255.6 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1 PF00133.22 EHU01603.1 - 1.4e-67 228.4 11.0 4.5e-27 94.6 0.6 6.0 1 1 4 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EHU01603.1 - 7.4e-32 110.6 0.1 1e-22 80.4 0.0 4.1 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EHU01603.1 - 2.5e-15 56.7 0.0 5.4e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1f PF01921.18 EHU01603.1 - 0.00023 20.2 0.0 0.22 10.4 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (K) tRNA-synt_1e PF01406.19 EHU01603.1 - 0.00037 20.0 0.0 0.48 9.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Glyco_hydro_15 PF00723.21 EHU01603.1 - 0.09 11.5 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 15 DUF1451 PF07295.11 EHU01604.1 - 8.8e-47 158.8 0.1 1e-46 158.6 0.1 1.0 1 0 0 1 1 1 1 Zinc-ribbon containing domain PhnA_Zn_Ribbon PF08274.12 EHU01604.1 - 0.0093 15.9 0.6 2.7 8.0 0.1 2.4 2 0 0 2 2 2 2 PhnA Zinc-Ribbon zinc_ribbon_10 PF10058.9 EHU01604.1 - 0.12 12.1 0.7 0.12 12.1 0.7 1.8 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Apolipoprotein PF01442.18 EHU01604.1 - 0.13 12.1 1.7 0.18 11.7 0.6 1.6 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain TF_Zn_Ribbon PF08271.12 EHU01604.1 - 6.8 6.3 7.2 8.2 6.0 0.2 2.7 3 0 0 3 3 3 0 TFIIB zinc-binding ABC_tran PF00005.27 EHU01605.1 - 2.3e-33 115.6 0.0 3.3e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EHU01605.1 - 6.1e-09 36.1 0.0 0.0015 18.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EHU01605.1 - 2.3e-07 30.5 0.2 2.4e-06 27.1 0.2 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EHU01605.1 - 4.9e-05 23.6 0.4 9e-05 22.8 0.4 1.8 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EHU01605.1 - 0.00013 22.0 0.2 0.00025 21.0 0.2 1.5 1 0 0 1 1 1 1 RsgA GTPase Rad17 PF03215.15 EHU01605.1 - 0.00013 22.0 0.0 0.00016 21.6 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 EHU01605.1 - 0.00026 21.4 0.0 0.00035 21.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EHU01605.1 - 0.0003 20.5 0.1 0.00057 19.6 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 EHU01605.1 - 0.00068 19.8 0.0 0.0011 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EHU01605.1 - 0.0023 17.9 0.4 0.022 14.7 0.0 2.4 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea Dynamin_N PF00350.23 EHU01605.1 - 0.0056 16.7 0.1 0.0073 16.4 0.1 1.3 1 0 0 1 1 1 1 Dynamin family DLIC PF05783.11 EHU01605.1 - 0.0059 15.5 0.1 0.0083 15.0 0.1 1.1 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) ABC_ATPase PF09818.9 EHU01605.1 - 0.0076 15.1 2.3 2 7.1 0.1 3.4 2 1 1 3 3 3 1 Predicted ATPase of the ABC class AAA PF00004.29 EHU01605.1 - 0.015 15.7 1.5 0.13 12.7 0.2 2.6 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 EHU01605.1 - 0.015 14.4 0.3 0.032 13.3 0.3 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Septin PF00735.18 EHU01605.1 - 0.015 14.6 0.6 0.027 13.7 0.1 1.6 2 0 0 2 2 2 0 Septin AAA_30 PF13604.6 EHU01605.1 - 0.018 14.8 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EHU01605.1 - 0.02 14.6 0.0 0.85 9.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 EHU01605.1 - 0.023 14.4 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 EHU01605.1 - 0.026 15.1 0.0 0.044 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EHU01605.1 - 0.026 14.2 0.3 0.09 12.5 0.1 1.9 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EHU01605.1 - 0.031 13.9 0.8 0.052 13.1 0.2 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 EHU01605.1 - 0.033 14.7 0.0 0.066 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 EHU01605.1 - 0.044 12.4 0.2 0.42 9.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EHU01605.1 - 0.047 13.9 0.4 3.1 8.1 0.4 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATPase PF06745.13 EHU01605.1 - 0.05 12.9 0.2 0.094 12.1 0.2 1.6 1 1 0 1 1 1 0 KaiC AAA_7 PF12775.7 EHU01605.1 - 0.052 13.1 0.3 0.082 12.4 0.3 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EHU01605.1 - 0.053 13.9 0.2 0.19 12.2 0.0 2.0 2 0 0 2 2 2 0 RNA helicase RNA12 PF10443.9 EHU01605.1 - 0.067 11.9 0.1 0.097 11.4 0.1 1.2 1 0 0 1 1 1 0 RNA12 protein Zeta_toxin PF06414.12 EHU01605.1 - 0.083 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.21 EHU01605.1 - 0.085 12.2 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 EHU01605.1 - 0.09 12.7 0.7 0.17 11.8 0.7 1.4 1 0 0 1 1 1 0 NTPase Herpes_Helicase PF02689.14 EHU01605.1 - 0.11 10.4 0.3 0.52 8.2 0.0 1.8 2 0 0 2 2 2 0 Helicase ATP_bind_1 PF03029.17 EHU01605.1 - 0.14 11.9 1.0 0.19 11.5 0.2 1.6 2 0 0 2 2 1 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 EHU01605.1 - 0.15 12.1 0.1 0.4 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain BPD_transp_1 PF00528.22 EHU01606.1 - 2.2e-17 63.4 18.7 2.2e-17 63.4 18.7 1.7 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 EHU01607.1 - 8.1e-28 97.4 6.2 8.1e-28 97.4 6.2 1.4 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component SBP_bac_3 PF00497.20 EHU01608.1 - 3.2e-45 154.3 0.5 3.9e-45 154.0 0.5 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.11 EHU01608.1 - 0.0045 17.0 0.4 0.015 15.2 0.1 2.0 1 1 1 2 2 2 1 NMT1/THI5 like Phosphonate-bd PF12974.7 EHU01608.1 - 0.0046 16.6 0.0 0.0065 16.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein Indigoidine_A PF04227.12 EHU01608.1 - 0.043 13.2 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 Indigoidine synthase A like protein GutM PF06923.11 EHU01608.1 - 0.12 12.5 0.2 2.1 8.5 0.0 2.4 2 1 0 2 2 2 0 Glucitol operon activator protein (GutM) DUF3991 PF13154.6 EHU01608.1 - 0.14 12.5 0.1 1.5 9.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3991) DUF4131 PF13567.6 EHU01609.1 - 1.2 8.7 6.1 1.2 8.8 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) HTH_Tnp_1 PF01527.20 EHU01610.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU01610.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU01610.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU01610.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHU01611.1 - 7.4e-39 131.7 0.0 8.3e-39 131.6 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein zf-IS66 PF13005.7 EHU01612.1 - 9.4e-14 51.5 0.5 2.5e-13 50.2 0.5 1.8 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU01612.1 - 1.1e-11 45.3 8.7 2.3e-11 44.3 8.7 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Csm1_N PF18504.1 EHU01612.1 - 0.0023 18.2 5.4 0.023 15.0 0.6 2.7 1 1 1 2 2 2 1 Csm1 N-terminal domain FAM184 PF15665.5 EHU01612.1 - 0.0025 17.6 5.8 0.0034 17.2 5.8 1.1 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B FUSC PF04632.12 EHU01612.1 - 0.0027 16.3 5.8 0.0028 16.3 5.8 1.0 1 0 0 1 1 1 1 Fusaric acid resistance protein family Phage_HK97_TLTM PF06120.11 EHU01612.1 - 0.0093 15.2 2.5 0.014 14.6 2.5 1.3 1 0 0 1 1 1 1 Tail length tape measure protein LXG PF04740.12 EHU01612.1 - 0.013 15.2 2.5 0.18 11.5 0.4 2.2 1 1 1 2 2 2 0 LXG domain of WXG superfamily Exonuc_VII_L PF02601.15 EHU01612.1 - 0.017 14.7 1.2 0.018 14.7 1.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit ERM PF00769.19 EHU01612.1 - 0.018 14.8 9.9 0.024 14.4 9.9 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Tho2 PF11262.8 EHU01612.1 - 0.021 14.0 2.2 0.022 14.0 1.4 1.3 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DHR10 PF18595.1 EHU01612.1 - 0.066 13.3 10.4 0.1 12.6 10.4 1.2 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF948 PF06103.11 EHU01612.1 - 0.084 13.1 1.5 15 5.9 0.2 2.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Zn-ribbon_8 PF09723.10 EHU01612.1 - 0.09 12.9 0.2 0.24 11.5 0.2 1.8 1 0 0 1 1 1 0 Zinc ribbon domain RD3 PF14473.6 EHU01612.1 - 0.098 12.5 2.3 0.14 11.9 2.3 1.2 1 0 0 1 1 1 0 RD3 protein G-gamma PF00631.22 EHU01612.1 - 0.12 12.4 0.6 6.4 6.9 0.1 2.6 1 1 1 2 2 2 0 GGL domain Troponin PF00992.20 EHU01612.1 - 0.15 12.3 5.5 0.27 11.5 5.5 1.4 1 1 0 1 1 1 0 Troponin TMPIT PF07851.13 EHU01612.1 - 0.19 11.0 2.9 0.26 10.5 2.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF3145 PF11343.8 EHU01612.1 - 0.2 11.2 0.7 0.44 10.1 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3145) ATG16 PF08614.11 EHU01612.1 - 0.23 11.7 10.3 0.62 10.3 2.1 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Lebercilin PF15619.6 EHU01612.1 - 0.27 10.9 10.4 0.57 9.8 10.4 1.5 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease HalX PF08663.10 EHU01612.1 - 0.29 11.5 7.0 0.071 13.4 3.0 2.0 2 0 0 2 2 2 0 HalX domain HAUS-augmin3 PF14932.6 EHU01612.1 - 0.39 10.2 7.5 1.1 8.7 7.5 1.7 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 Mt_ATP-synt_D PF05873.12 EHU01612.1 - 0.54 10.1 3.3 4.3 7.2 0.1 2.1 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) DUF1192 PF06698.11 EHU01612.1 - 0.79 9.8 9.9 0.93 9.6 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) USP8_interact PF08941.10 EHU01612.1 - 0.8 9.5 4.2 1.6 8.5 4.2 1.5 1 1 0 1 1 1 0 USP8 interacting OmpH PF03938.14 EHU01612.1 - 0.82 10.0 7.4 1.2 9.5 7.4 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 EHU01612.1 - 0.82 10.3 9.6 4.5e+02 1.6 9.6 2.8 1 1 0 1 1 1 0 SlyX TMF_DNA_bd PF12329.8 EHU01612.1 - 1.6 8.8 8.6 3 7.9 0.5 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding HAUS6_N PF14661.6 EHU01612.1 - 6.2 6.3 7.8 12 5.4 7.5 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus MerR-DNA-bind PF09278.11 EHU01612.1 - 7.4 7.2 13.1 7.8 7.1 2.2 2.6 2 1 0 2 2 2 0 MerR, DNA binding FlxA PF14282.6 EHU01613.1 - 5.5e-26 90.5 23.3 7e-26 90.2 23.3 1.1 1 0 0 1 1 1 1 FlxA-like protein Peptidase_M16 PF00675.20 EHU01613.1 - 0.0012 18.8 1.2 0.0015 18.5 1.2 1.1 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) FapA PF03961.13 EHU01613.1 - 0.0041 15.8 6.1 0.0046 15.6 6.1 1.0 1 0 0 1 1 1 1 Flagellar Assembly Protein A Allexi_40kDa PF05549.11 EHU01613.1 - 0.0076 15.8 6.1 0.0074 15.8 6.1 1.0 1 0 0 1 1 1 1 Allexivirus 40kDa protein LPP PF04728.13 EHU01613.1 - 0.016 15.6 13.6 0.28 11.6 0.7 2.5 1 1 1 2 2 2 0 Lipoprotein leucine-zipper BBP1_C PF15272.6 EHU01613.1 - 0.016 15.0 7.0 0.017 14.9 7.0 1.0 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Cob_adeno_trans PF01923.18 EHU01613.1 - 0.017 15.3 1.4 0.021 15.0 1.4 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase tRNA-synt_1_2 PF13603.6 EHU01613.1 - 0.022 14.3 3.0 0.041 13.4 1.6 1.7 1 1 1 2 2 2 0 Leucyl-tRNA synthetase, Domain 2 ADIP PF11559.8 EHU01613.1 - 0.023 14.8 14.5 0.03 14.4 14.5 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding SKA2 PF16740.5 EHU01613.1 - 0.036 13.8 8.7 0.046 13.5 8.7 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 DUF5082 PF16888.5 EHU01613.1 - 0.041 14.2 3.8 0.041 14.2 3.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF4795 PF16043.5 EHU01613.1 - 0.058 13.0 9.0 0.064 12.9 9.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) MCU PF04678.13 EHU01613.1 - 0.059 13.5 2.6 0.07 13.2 2.6 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter AAA_13 PF13166.6 EHU01613.1 - 0.06 12.0 8.3 0.07 11.8 8.3 1.1 1 0 0 1 1 1 0 AAA domain DUF2526 PF10735.9 EHU01613.1 - 0.061 13.5 5.8 0.1 12.8 5.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2526) Fungal_trans_2 PF11951.8 EHU01613.1 - 0.062 12.1 1.7 0.069 11.9 1.7 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain HemX PF04375.14 EHU01613.1 - 0.065 12.5 11.9 0.073 12.4 11.9 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4349 PF14257.6 EHU01613.1 - 0.067 12.6 6.0 0.087 12.3 6.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF3450 PF11932.8 EHU01613.1 - 0.09 12.1 12.4 0.091 12.0 12.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) RRP36 PF06102.12 EHU01613.1 - 0.095 12.7 8.5 0.13 12.3 8.5 1.3 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 BRI3BP PF14965.6 EHU01613.1 - 0.13 11.8 1.6 1.9 7.9 0.8 2.0 1 1 1 2 2 2 0 Negative regulator of p53/TP53 Csm1_N PF18504.1 EHU01613.1 - 0.13 12.6 14.5 1.7 9.0 0.3 2.2 1 1 1 2 2 2 0 Csm1 N-terminal domain DUF4407 PF14362.6 EHU01613.1 - 0.14 11.5 12.2 0.19 11.1 12.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IHHNV_capsid PF16530.5 EHU01613.1 - 0.14 11.2 0.6 0.16 11.0 0.6 1.0 1 0 0 1 1 1 0 Infectious hypodermal and haematopoietic necrosis virus, capsid V_ATPase_I PF01496.19 EHU01613.1 - 0.18 9.7 6.2 0.19 9.6 6.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SprA-related PF12118.8 EHU01613.1 - 0.27 10.3 15.9 0.3 10.2 15.9 1.1 1 0 0 1 1 1 0 SprA-related family FUSC PF04632.12 EHU01613.1 - 0.3 9.6 1.5 0.34 9.4 1.5 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family PBP_sp32 PF07222.12 EHU01613.1 - 0.32 10.4 6.8 0.38 10.2 6.8 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Tho2 PF11262.8 EHU01613.1 - 0.32 10.2 7.8 0.37 10.0 7.8 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 TMPIT PF07851.13 EHU01613.1 - 0.36 10.0 6.3 0.44 9.7 6.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF4140 PF13600.6 EHU01613.1 - 0.41 11.1 12.8 0.92 10.0 0.4 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF724 PF05266.14 EHU01613.1 - 0.45 10.3 13.3 1.4 8.7 13.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF724) SlyX PF04102.12 EHU01613.1 - 0.46 11.1 12.7 0.79 10.4 0.2 2.2 1 1 1 2 2 2 0 SlyX DASH_Hsk3 PF08227.11 EHU01613.1 - 0.49 10.8 8.5 5 7.6 0.1 2.9 2 2 0 2 2 2 0 DASH complex subunit Hsk3 like DUF948 PF06103.11 EHU01613.1 - 0.54 10.6 4.6 0.72 10.1 4.6 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF1682 PF07946.14 EHU01613.1 - 0.56 9.3 8.9 0.77 8.9 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) ProSAAS PF07259.12 EHU01613.1 - 0.7 9.8 3.8 0.33 10.9 1.9 1.4 2 0 0 2 2 1 0 ProSAAS precursor CCDC-167 PF15188.6 EHU01613.1 - 0.79 10.1 7.0 1.6 9.1 6.8 1.6 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 MerR-DNA-bind PF09278.11 EHU01613.1 - 0.83 10.2 9.1 10 6.7 6.0 2.2 1 1 1 2 2 2 0 MerR, DNA binding YlqD PF11068.8 EHU01613.1 - 1.2 9.5 19.3 2.4 8.5 15.1 2.0 1 1 1 2 2 2 0 YlqD protein FemAB PF02388.16 EHU01613.1 - 1.3 7.8 9.3 1.5 7.6 9.3 1.1 1 0 0 1 1 1 0 FemAB family DUF3682 PF12446.8 EHU01613.1 - 1.4 9.4 11.6 2.5 8.6 11.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3682) DivIC PF04977.15 EHU01613.1 - 1.5 8.6 17.9 2 8.3 1.7 2.5 1 1 1 2 2 2 0 Septum formation initiator Spc24 PF08286.11 EHU01613.1 - 1.6 9.0 12.8 2.3 8.5 2.1 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Med9 PF07544.13 EHU01613.1 - 1.7 8.8 12.4 4 7.6 12.4 1.7 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF5320 PF17253.2 EHU01613.1 - 1.7 9.7 7.7 28 5.9 0.1 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5320) MMPL PF03176.15 EHU01613.1 - 2.3 7.1 4.5 3 6.7 4.5 1.1 1 0 0 1 1 1 0 MMPL family DUF3138 PF11336.8 EHU01613.1 - 3.3 6.2 10.2 3.3 6.2 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) YabA PF06156.13 EHU01613.1 - 3.4 8.3 8.7 6.3 7.5 8.7 1.4 1 1 0 1 1 1 0 Initiation control protein YabA Swi5 PF07061.11 EHU01613.1 - 4.3 7.5 14.3 1.7 8.8 2.3 2.2 1 1 1 2 2 2 0 Swi5 DUF2802 PF10975.8 EHU01613.1 - 7.6 6.7 11.5 3.9 7.7 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2802) DUF5339 PF17274.2 EHU01613.1 - 9 7.2 18.7 19 6.2 0.1 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5339) LysR_substrate PF03466.20 EHU01614.1 - 5.9e-42 143.4 1.6 9.7e-42 142.7 1.6 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EHU01614.1 - 7.9e-22 77.0 1.4 7.9e-22 77.0 1.4 3.1 4 0 0 4 4 4 1 Bacterial regulatory helix-turn-helix protein, lysR family P22_Cro PF14549.6 EHU01614.1 - 0.051 13.4 0.6 0.1 12.4 0.2 1.7 2 0 0 2 2 2 0 DNA-binding transcriptional regulator Cro HTH_24 PF13412.6 EHU01614.1 - 0.09 12.4 0.0 0.27 10.8 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding SBF_like PF13593.6 EHU01615.1 - 1e-97 327.2 18.6 1.2e-97 327.1 18.6 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 EHU01615.1 - 8.1e-10 38.7 6.3 8.1e-10 38.7 6.3 2.3 3 1 0 3 3 3 1 Sodium Bile acid symporter family QSregVF_b PF12843.7 EHU01616.1 - 3e-30 103.9 0.2 3.2e-30 103.8 0.2 1.0 1 0 0 1 1 1 1 Putative quorum-sensing-regulated virulence factor DNA_ligase_aden PF01653.18 EHU01617.1 - 6.8e-140 465.7 0.0 1.4e-139 464.6 0.0 1.5 2 0 0 2 2 2 1 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 EHU01617.1 - 2.1e-35 120.5 2.5 2.1e-35 120.5 2.5 2.3 3 0 0 3 3 3 1 NAD-dependent DNA ligase OB-fold domain HHH_2 PF12826.7 EHU01617.1 - 1.2e-24 86.2 0.1 2.3e-21 75.7 0.2 2.9 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_5 PF14520.6 EHU01617.1 - 2.5e-14 53.6 0.2 6.6e-07 29.8 0.0 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix domain BRCT PF00533.26 EHU01617.1 - 2.6e-14 53.3 0.0 6.7e-14 52.0 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_ZBD PF03119.16 EHU01617.1 - 5e-11 42.4 4.1 1.6e-10 40.8 4.1 2.0 1 0 0 1 1 1 1 NAD-dependent DNA ligase C4 zinc finger domain PTCB-BRCT PF12738.7 EHU01617.1 - 1.3e-06 28.3 0.0 6.2e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 twin BRCT domain DUF4874 PF16173.5 EHU01617.1 - 0.00098 18.8 0.4 0.0027 17.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4874) Prok-E2_C PF14459.6 EHU01617.1 - 0.02 15.0 0.3 0.054 13.6 0.1 1.8 2 0 0 2 2 2 0 Prokaryotic E2 family C 5_3_exonuc PF01367.20 EHU01617.1 - 0.028 15.0 0.0 0.15 12.7 0.0 2.2 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold HHH PF00633.23 EHU01617.1 - 0.084 12.8 0.0 1.3 9.0 0.0 2.9 3 0 0 3 3 3 0 Helix-hairpin-helix motif ZipA_C PF04354.13 EHU01618.1 - 2.8e-50 169.4 0.1 3.6e-50 169.1 0.1 1.1 1 0 0 1 1 1 1 ZipA, C-terminal FtsZ-binding domain EI24 PF07264.11 EHU01619.1 - 7.2e-43 146.9 15.1 8.3e-43 146.7 15.1 1.0 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF997 PF06196.12 EHU01619.1 - 3.9 7.6 10.2 43 4.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF997) PALP PF00291.25 EHU01620.1 - 2.4e-68 230.7 0.6 2.7e-68 230.5 0.6 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peripla_BP_6 PF13458.6 EHU01620.1 - 0.034 13.8 0.5 1 9.0 0.1 2.6 3 0 0 3 3 3 0 Periplasmic binding protein ADH_zinc_N PF00107.26 EHU01620.1 - 0.048 13.6 0.4 0.38 10.7 0.4 2.2 1 1 0 1 1 1 0 Zinc-binding dehydrogenase DFP PF04127.15 EHU01620.1 - 0.09 12.6 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein PTS-HPr PF00381.19 EHU01621.1 - 1.3e-28 99.1 0.3 1.4e-28 99.0 0.3 1.0 1 0 0 1 1 1 1 PTS HPr component phosphorylation site PEP-utilizers_C PF02896.18 EHU01622.1 - 3.5e-124 413.7 0.1 4.7e-124 413.3 0.1 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilisers_N PF05524.13 EHU01622.1 - 2.9e-31 108.0 5.5 2.9e-31 108.0 5.5 2.9 4 0 0 4 4 4 1 PEP-utilising enzyme, N-terminal PEP-utilizers PF00391.23 EHU01622.1 - 4.9e-25 87.0 0.1 1.8e-24 85.3 0.1 2.0 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain MHB PF16525.5 EHU01622.1 - 0.43 10.9 2.9 1.6 9.0 0.1 2.8 3 0 0 3 3 3 0 Haemophore, haem-binding PTS_EIIA_1 PF00358.20 EHU01623.1 - 9.6e-50 167.6 2.1 1.2e-49 167.3 2.1 1.1 1 0 0 1 1 1 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Biotin_lipoyl_2 PF13533.6 EHU01623.1 - 0.0017 18.1 0.4 0.022 14.6 0.0 2.6 3 0 0 3 3 3 1 Biotin-lipoyl like Peptidase_M23 PF01551.22 EHU01623.1 - 0.028 14.6 0.4 0.29 11.3 0.1 2.2 1 1 1 2 2 2 0 Peptidase family M23 Biotin_lipoyl PF00364.22 EHU01623.1 - 0.09 12.6 5.2 1.4 8.8 0.1 3.4 4 0 0 4 4 4 0 Biotin-requiring enzyme HATPase_c PF02518.26 EHU01624.1 - 7.3e-18 65.1 0.0 1.2e-17 64.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 EHU01624.1 - 8.7e-13 48.4 0.3 3.3e-12 46.6 0.3 2.1 1 0 0 1 1 1 1 HAMP domain HisKA PF00512.25 EHU01624.1 - 7.8e-12 45.1 7.1 1.8e-11 43.9 3.6 2.7 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 EHU01624.1 - 0.00027 20.9 0.0 0.0006 19.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HisKA_3 PF07730.13 EHU01624.1 - 0.042 14.4 2.6 0.11 13.0 1.8 2.2 1 1 0 1 1 1 0 Histidine kinase THOC7 PF05615.13 EHU01624.1 - 0.16 12.2 0.5 0.27 11.5 0.5 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 Response_reg PF00072.24 EHU01625.1 - 2.7e-21 75.8 0.0 4.3e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 EHU01625.1 - 8e-21 73.9 0.5 3.2e-20 72.0 0.0 2.0 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal PALP PF00291.25 EHU01626.1 - 1.6e-72 244.4 0.2 2.8e-72 243.6 0.2 1.4 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ABC_tran PF00005.27 EHU01627.1 - 6e-38 130.5 0.0 9e-38 129.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EHU01627.1 - 2e-09 37.2 0.0 2.8e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EHU01627.1 - 3.3e-09 37.0 0.7 0.001 18.9 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system CysA_C_terminal PF17850.1 EHU01627.1 - 8.8e-05 23.0 1.1 0.00044 20.8 0.2 2.7 4 0 0 4 4 1 1 CysA C-terminal regulatory domain AAA_16 PF13191.6 EHU01627.1 - 0.0001 22.7 0.5 0.00072 20.0 0.5 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EHU01627.1 - 0.00023 21.5 0.2 0.0011 19.3 0.2 1.9 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EHU01627.1 - 0.0006 19.8 0.1 0.0011 18.9 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase NACHT PF05729.12 EHU01627.1 - 0.00062 19.7 0.3 0.029 14.3 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 EHU01627.1 - 0.00083 19.8 0.0 0.01 16.2 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DLIC PF05783.11 EHU01627.1 - 0.00093 18.1 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) ATPase PF06745.13 EHU01627.1 - 0.00099 18.5 0.0 0.85 8.9 0.0 2.1 2 0 0 2 2 2 2 KaiC TOBE_3 PF12857.7 EHU01627.1 - 0.0011 18.8 0.1 0.0059 16.5 0.0 2.2 1 1 1 2 2 2 1 TOBE-like domain AAA_24 PF13479.6 EHU01627.1 - 0.0012 18.6 0.2 0.24 11.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EHU01627.1 - 0.003 17.2 0.0 0.0073 16.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain TniB PF05621.11 EHU01627.1 - 0.0043 16.5 0.0 0.26 10.7 0.0 2.3 2 1 0 2 2 2 1 Bacterial TniB protein SbcCD_C PF13558.6 EHU01627.1 - 0.0064 16.7 0.1 0.067 13.4 0.1 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 EHU01627.1 - 0.0085 16.4 0.0 0.028 14.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EHU01627.1 - 0.0097 16.5 0.0 0.027 15.0 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_23 PF13476.6 EHU01627.1 - 0.011 16.2 0.1 0.02 15.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EHU01627.1 - 0.012 15.4 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain RecA PF00154.21 EHU01627.1 - 0.016 14.7 0.1 0.097 12.1 0.1 2.0 1 1 0 1 1 1 0 recA bacterial DNA recombination protein PhoH PF02562.16 EHU01627.1 - 0.016 14.7 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.6 EHU01627.1 - 0.017 15.3 0.4 0.093 12.9 0.4 2.1 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EHU01627.1 - 0.027 14.0 0.2 0.48 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 EHU01627.1 - 0.036 12.9 0.4 2 7.1 0.0 2.7 2 1 0 2 2 2 0 Predicted ATPase of the ABC class TsaE PF02367.17 EHU01627.1 - 0.043 13.8 0.0 0.075 13.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EHU01627.1 - 0.048 13.7 0.0 0.3 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EHU01627.1 - 0.063 13.3 0.1 0.3 11.1 0.0 2.1 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) cobW PF02492.19 EHU01627.1 - 0.072 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.20 EHU01627.1 - 0.086 12.0 0.0 0.095 11.8 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit TOBE_2 PF08402.10 EHU01627.1 - 0.12 12.6 0.6 0.48 10.6 0.0 2.4 3 0 0 3 3 1 0 TOBE domain DEAD PF00270.29 EHU01627.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase SRP54 PF00448.22 EHU01627.1 - 0.14 11.8 0.0 0.45 10.1 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain T2SSE PF00437.20 EHU01627.1 - 0.14 11.2 0.1 0.66 9.0 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein Roc PF08477.13 EHU01627.1 - 0.15 12.3 0.0 2.5 8.4 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase APS_kinase PF01583.20 EHU01627.1 - 0.17 11.8 0.1 21 4.9 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase NB-ARC PF00931.22 EHU01627.1 - 0.19 10.8 0.0 0.36 10.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 EHU01627.1 - 0.21 11.4 0.0 0.33 10.8 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea BPD_transp_1 PF00528.22 EHU01628.1 - 4e-13 49.5 14.4 4e-13 49.5 14.4 2.3 1 1 1 2 2 2 2 Binding-protein-dependent transport system inner membrane component Rhabdo_glycop PF00974.18 EHU01628.1 - 0.037 12.5 0.2 0.053 12.0 0.2 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein BPD_transp_1 PF00528.22 EHU01629.1 - 1.6e-32 112.8 11.9 1.6e-32 112.8 11.9 1.8 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Abhydrolase_9_N PF15420.6 EHU01629.1 - 1.1 9.2 13.2 0.045 13.7 1.2 2.4 1 1 2 3 3 3 0 Alpha/beta-hydrolase family N-terminus SBP_bac_11 PF13531.6 EHU01630.1 - 2.1e-43 148.7 0.2 2.6e-43 148.4 0.2 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 EHU01630.1 - 2.5e-15 57.2 3.4 3.7e-15 56.7 3.4 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 EHU01630.1 - 2.1e-11 44.2 3.9 5.3e-11 42.8 3.6 1.5 1 1 1 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 EHU01630.1 - 5.6e-09 35.8 0.3 9e-09 35.1 0.3 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein PBP_like_2 PF12849.7 EHU01630.1 - 6.9e-05 22.7 0.2 0.0011 18.8 0.2 2.1 1 1 0 1 1 1 1 PBP superfamily domain PBP_like PF12727.7 EHU01630.1 - 0.0013 17.9 0.0 0.002 17.3 0.0 1.3 1 0 0 1 1 1 1 PBP superfamily domain DUF1131 PF06572.12 EHU01631.1 - 7.9e-70 234.0 0.2 9.3e-70 233.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1131) DUF2919 PF11143.8 EHU01632.1 - 2.1e-43 148.1 11.1 2.6e-43 147.9 11.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2919) Acetyltransf_1 PF00583.25 EHU01633.1 - 2.8e-20 72.7 0.1 3.6e-20 72.3 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EHU01633.1 - 4.6e-15 55.7 0.0 6.3e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EHU01633.1 - 1.7e-13 50.8 0.2 2.7e-13 50.2 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EHU01633.1 - 1.9e-09 37.7 0.1 6e-08 32.8 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EHU01633.1 - 8.4e-09 35.3 0.0 1.2e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_6 PF13480.7 EHU01633.1 - 4e-07 30.3 0.5 5.2e-07 29.9 0.5 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EHU01633.1 - 0.0023 18.6 0.0 0.003 18.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EHU01633.1 - 0.028 14.6 0.0 0.071 13.2 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EHU01633.1 - 0.074 12.5 0.0 0.096 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase GNAT_acetyltran PF12746.7 EHU01633.1 - 0.11 12.0 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_CG PF14542.6 EHU01633.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Amidase_3 PF01520.18 EHU01635.1 - 1.6e-49 168.4 0.0 2.6e-49 167.7 0.0 1.3 1 1 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase Coprogen_oxidas PF01218.18 EHU01636.1 - 5.6e-134 445.5 0.0 6.3e-134 445.3 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase TAL_FSA PF00923.19 EHU01637.1 - 4.1e-100 334.8 0.0 4.6e-100 334.7 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Transketolase_N PF00456.21 EHU01638.1 - 6.6e-171 567.7 0.1 9.4e-171 567.2 0.1 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EHU01638.1 - 4.1e-48 163.4 0.3 1.1e-47 162.0 0.1 1.8 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EHU01638.1 - 1.8e-18 66.6 0.1 4.6e-18 65.3 0.1 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 EHU01638.1 - 7.9e-05 22.0 0.0 0.039 13.1 0.0 2.4 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 EHU01638.1 - 0.00053 19.0 0.0 0.001 18.1 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 EHU01638.1 - 0.0028 17.5 0.1 0.82 9.4 0.1 2.7 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain HlyD PF00529.20 EHU01638.1 - 0.63 10.0 2.4 0.37 10.7 0.4 1.4 1 1 0 1 1 1 0 HlyD membrane-fusion protein of T1SS 2HCT PF03390.15 EHU01640.1 - 2.1e-112 375.8 25.8 2.7e-112 375.4 25.8 1.0 1 0 0 1 1 1 1 2-hydroxycarboxylate transporter family HK97-gp10_like PF04883.12 EHU01640.1 - 4e-15 56.6 0.4 8.6e-15 55.5 0.4 1.5 1 0 0 1 1 1 1 Bacteriophage HK97-gp10, putative tail-component Phage_H_T_join PF05521.11 EHU01641.1 - 1.5e-18 67.1 0.1 1.7e-18 66.9 0.1 1.0 1 0 0 1 1 1 1 Phage head-tail joining protein Phage_capsid PF05065.13 EHU01642.1 - 3.6e-53 180.7 0.2 5.1e-53 180.2 0.2 1.2 1 0 0 1 1 1 1 Phage capsid family YPEB PF14620.6 EHU01642.1 - 0.0053 16.1 1.7 0.0087 15.4 1.7 1.3 1 0 0 1 1 1 1 YpeB sporulation Peptidase_S78 PF04586.17 EHU01643.1 - 8e-30 104.2 0.0 1.1e-29 103.6 0.0 1.2 1 0 0 1 1 1 1 Caudovirus prohead serine protease Phage_portal PF04860.12 EHU01644.1 - 4.3e-82 275.8 0.0 4.8e-82 275.7 0.0 1.0 1 0 0 1 1 1 1 Phage portal protein Terminase_1 PF03354.15 EHU01645.1 - 1.1e-46 159.4 0.0 1.3e-46 159.1 0.0 1.0 1 0 0 1 1 1 1 Phage Terminase AATF-Che1 PF13339.6 EHU01646.1 - 0.026 15.2 2.8 0.032 14.9 2.8 1.1 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor ALMT PF11744.8 EHU01646.1 - 0.059 12.2 2.1 0.064 12.1 2.1 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF1129 PF06570.11 EHU01646.1 - 0.087 12.3 1.3 0.097 12.2 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DWNN PF08783.11 EHU01646.1 - 0.1 12.9 2.8 0.56 10.5 2.8 2.0 1 1 0 1 1 1 0 DWNN domain CorA PF01544.18 EHU01646.1 - 1.2 8.4 5.4 1.3 8.3 5.4 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Selenoprotein_S PF06936.11 EHU01646.1 - 1.8 8.3 7.0 2.1 8.1 7.0 1.0 1 0 0 1 1 1 0 Selenoprotein S (SelS) TPX2 PF06886.11 EHU01646.1 - 2.9 8.2 11.0 0.93 9.8 3.0 2.3 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) DUF4407 PF14362.6 EHU01646.1 - 3.3 7.0 7.3 4 6.7 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HNH PF01844.23 EHU01648.1 - 2e-05 24.7 1.9 0.00088 19.4 1.9 2.2 1 1 0 1 1 1 1 HNH endonuclease Glyco_transf_25 PF01755.17 EHU01649.1 - 0.1 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) Glyco_tranf_2_3 PF13641.6 EHU01650.1 - 0.0053 16.7 0.0 0.33 10.8 0.0 2.7 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EHU01650.1 - 0.065 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 Complex1_51K PF01512.17 EHU01651.1 - 0.087 12.7 0.0 0.2 11.5 0.0 1.6 1 1 0 1 1 1 0 Respiratory-chain NADH dehydrogenase 51 Kd subunit DnaJ-X PF14308.6 EHU01651.1 - 0.13 11.7 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 X-domain of DnaJ-containing KdpC PF02669.15 EHU01652.1 - 0.85 9.4 2.3 12 5.7 0.1 2.4 3 0 0 3 3 3 0 K+-transporting ATPase, c chain Tropomyosin_1 PF12718.7 EHU01653.1 - 2.2e-05 24.6 2.9 2.8e-05 24.3 2.9 1.2 1 0 0 1 1 1 1 Tropomyosin like ESAG1 PF03238.13 EHU01653.1 - 0.00032 20.2 0.4 0.00038 20.0 0.4 1.1 1 0 0 1 1 1 1 ESAG protein UPF0242 PF06785.11 EHU01653.1 - 0.0025 18.0 0.0 0.003 17.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus CENP-H PF05837.12 EHU01653.1 - 0.014 15.8 2.0 0.014 15.8 2.0 1.9 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF948 PF06103.11 EHU01653.1 - 0.016 15.4 1.5 0.056 13.7 0.9 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) MCM3AP_GANP PF16769.5 EHU01653.1 - 0.026 12.8 0.6 0.029 12.6 0.6 1.0 1 0 0 1 1 1 0 MCM3AP domain of GANP DUF4763 PF15960.5 EHU01653.1 - 0.045 13.1 3.4 0.058 12.7 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Gp-FAR-1 PF05823.12 EHU01653.1 - 0.049 14.0 1.2 0.064 13.6 1.2 1.2 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Spc7 PF08317.11 EHU01653.1 - 0.06 12.2 2.7 0.07 12.0 2.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FUSC PF04632.12 EHU01653.1 - 0.1 11.1 0.8 0.11 11.0 0.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DivIC PF04977.15 EHU01653.1 - 0.16 11.7 10.5 1.3 8.8 1.1 2.8 1 1 1 2 2 2 0 Septum formation initiator Prominin PF05478.11 EHU01653.1 - 0.31 8.9 1.6 0.36 8.7 1.6 1.1 1 0 0 1 1 1 0 Prominin TMF_DNA_bd PF12329.8 EHU01653.1 - 0.4 10.7 5.1 0.77 9.8 5.1 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding YabA PF06156.13 EHU01653.1 - 0.72 10.5 3.5 1.1 9.9 0.4 2.1 1 1 1 2 2 2 0 Initiation control protein YabA ATG16 PF08614.11 EHU01653.1 - 0.72 10.0 11.1 0.28 11.4 5.7 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) HAP1_N PF04849.13 EHU01653.1 - 0.81 8.8 6.9 2 7.5 1.3 1.9 1 1 0 2 2 2 0 HAP1 N-terminal conserved region ADIP PF11559.8 EHU01653.1 - 0.98 9.5 8.5 1.8 8.6 7.9 1.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF883 PF05957.13 EHU01653.1 - 1.6 9.3 9.2 2.6 8.7 4.6 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF3450 PF11932.8 EHU01653.1 - 2 7.7 9.3 2 7.6 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) SlyX PF04102.12 EHU01653.1 - 3 8.5 5.7 7.7 7.2 3.3 2.4 1 1 1 2 2 2 0 SlyX Phage_lysozyme PF00959.19 EHU01654.1 - 3.9e-26 91.7 0.0 4.6e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Phage lysozyme DUF4376 PF14301.6 EHU01654.1 - 0.097 13.0 0.0 0.22 11.9 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4376) Phage_antitermQ PF06530.12 EHU01655.1 - 6.7e-16 58.3 0.1 7.7e-16 58.1 0.1 1.0 1 0 0 1 1 1 1 Phage antitermination protein Q Sigma70_r4_2 PF08281.12 EHU01655.1 - 0.0093 15.6 0.1 0.019 14.6 0.0 1.6 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_10 PF04967.12 EHU01655.1 - 0.036 13.9 0.0 0.057 13.2 0.0 1.2 1 0 0 1 1 1 0 HTH DNA binding domain HTH_28 PF13518.6 EHU01655.1 - 0.12 12.5 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_50 PF18024.1 EHU01655.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Prim_Zn_Ribbon PF08273.12 EHU01656.1 - 1.1e-11 44.7 8.2 2e-11 43.9 8.2 1.4 1 0 0 1 1 1 1 Zinc-binding domain of primase-helicase Toprim_3 PF13362.6 EHU01656.1 - 5.2e-11 42.8 0.0 1e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Helicase_C PF00271.31 EHU01657.1 - 1.8e-07 31.5 0.0 4.3e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EHU01657.1 - 0.0058 16.7 0.0 0.013 15.6 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DZR PF12773.7 EHU01657.1 - 0.068 13.2 1.1 0.14 12.2 1.1 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-HIT PF04438.16 EHU01657.1 - 1 9.3 4.0 1.7 8.6 4.0 1.3 1 0 0 1 1 1 0 HIT zinc finger PrsW-protease PF13367.6 EHU01660.1 - 0.13 11.7 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 PrsW family intramembrane metalloprotease RsbU_N PF08673.10 EHU01661.1 - 0.066 13.3 0.0 0.095 12.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain DDE_Tnp_IS66 PF03050.14 EHU01665.1 - 1.3e-97 326.7 4.3 3.8e-97 325.1 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU01665.1 - 3e-16 59.4 0.1 1.3e-15 57.3 0.1 2.3 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU01665.1 - 1.4e-14 54.2 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU01665.1 - 6.3e-10 39.7 8.7 1.3e-09 38.6 8.7 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Phage_HK97_TLTM PF06120.11 EHU01665.1 - 0.015 14.5 0.7 0.028 13.6 0.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHU01665.1 - 0.03 14.6 4.4 0.13 12.6 0.7 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain UME PF08064.13 EHU01665.1 - 0.035 14.0 0.3 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain FUSC PF04632.12 EHU01665.1 - 0.038 12.6 7.0 0.06 11.9 7.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tho2 PF11262.8 EHU01665.1 - 0.039 13.2 0.5 0.064 12.5 0.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FAM184 PF15665.5 EHU01665.1 - 0.071 12.9 7.6 0.11 12.2 7.6 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Exonuc_VII_L PF02601.15 EHU01665.1 - 0.093 12.3 2.4 0.1 12.2 0.9 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit HalX PF08663.10 EHU01665.1 - 0.11 12.8 2.3 0.29 11.5 2.3 1.7 1 0 0 1 1 1 0 HalX domain ERM PF00769.19 EHU01665.1 - 0.17 11.7 10.2 0.28 11.0 10.2 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family LXG PF04740.12 EHU01665.1 - 0.35 10.5 2.5 1 9.0 0.3 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily Zn-ribbon_8 PF09723.10 EHU01665.1 - 0.46 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DHR10 PF18595.1 EHU01665.1 - 0.52 10.4 10.4 0.91 9.6 10.4 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF1192 PF06698.11 EHU01665.1 - 1.1 9.4 6.1 4 7.6 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHU01665.1 - 1.1 8.5 2.7 1.6 7.9 2.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHU01665.1 - 2.3 7.7 7.2 5.2 6.6 7.2 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 CREPT PF16566.5 EHU01665.1 - 7.3 6.8 8.2 3.4 7.8 5.1 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour SlyX PF04102.12 EHU01665.1 - 9 7.0 8.8 16 6.2 2.2 3.0 1 1 1 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHU01666.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHU01667.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU01667.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU01667.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU01667.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix Cortex-I_coil PF09304.10 EHU01668.1 - 0.11 12.7 0.1 0.18 12.0 0.1 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil Peptidase_C92 PF05708.12 EHU01673.1 - 0.12 12.5 0.2 0.13 12.4 0.2 1.1 1 0 0 1 1 1 0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family LexA_DNA_bind PF01726.16 EHU01675.1 - 1.3e-19 69.7 0.1 4.8e-19 67.9 0.1 1.8 2 0 0 2 2 2 1 LexA DNA binding domain Rrf2 PF02082.20 EHU01675.1 - 0.0078 16.5 0.1 0.017 15.4 0.1 1.6 1 1 1 2 2 2 1 Transcriptional regulator DUF1198 PF06711.11 EHU01676.1 - 6.4e-60 201.3 0.2 7.6e-60 201.1 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1198) THF_DHG_CYH_C PF02882.19 EHU01677.1 - 8.3e-69 230.0 0.0 1.3e-68 229.4 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EHU01677.1 - 8.2e-39 132.5 0.1 1.2e-38 131.9 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain UDPG_MGDP_dh_N PF03721.14 EHU01677.1 - 0.071 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain S4_2 PF13275.6 EHU01678.1 - 6.6e-24 83.5 0.1 6.8e-24 83.5 0.1 1.0 1 0 0 1 1 1 1 S4 domain S4 PF01479.25 EHU01678.1 - 0.01 15.5 0.1 0.018 14.7 0.0 1.5 2 0 0 2 2 2 0 S4 domain AAA_21 PF13304.6 EHU01679.1 - 5.4e-24 85.6 0.0 2.3e-16 60.5 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EHU01679.1 - 3.9e-16 59.7 0.0 1.1e-09 38.5 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 EHU01679.1 - 3.2e-14 52.9 0.0 4.9e-08 32.7 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EHU01679.1 - 3.2e-07 31.0 0.0 5.1e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF2813 PF11398.8 EHU01679.1 - 6.6e-06 25.6 0.0 1.3e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2813) ABC_tran PF00005.27 EHU01679.1 - 0.0014 19.1 0.0 0.012 16.1 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_30 PF13604.6 EHU01679.1 - 0.022 14.5 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 EHU01679.1 - 0.071 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain tRNA-synt_1e PF01406.19 EHU01680.1 - 2.3e-142 473.7 0.0 3e-142 473.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DALR_2 PF09190.11 EHU01680.1 - 6e-27 93.9 0.9 4.7e-26 91.0 0.4 2.7 2 0 0 2 2 2 1 DALR domain tRNA-synt_1g PF09334.11 EHU01680.1 - 1.3e-13 50.5 1.1 9.3e-06 24.6 0.0 2.3 2 1 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EHU01680.1 - 4.2e-07 28.6 0.1 6.2e-06 24.7 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 EHU01680.1 - 3.6e-05 22.8 0.0 0.0071 15.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (K) Mut7-C PF01927.16 EHU01680.1 - 0.026 14.6 0.0 0.054 13.6 0.0 1.5 1 0 0 1 1 1 0 Mut7-C RNAse domain Pro_isomerase PF00160.21 EHU01681.1 - 1.4e-48 165.2 1.7 1.5e-48 165.0 1.7 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Metallophos PF00149.28 EHU01682.1 - 1.5e-10 42.0 0.1 1.9e-10 41.6 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EHU01682.1 - 1.3e-09 38.5 1.5 9.2e-09 35.7 1.5 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Peptidase_S76 PF13611.6 EHU01682.1 - 0.15 12.3 0.3 0.46 10.8 0.2 1.7 1 1 1 2 2 2 0 Serine peptidase of plant viral polyprotein, P1 AIRC PF00731.20 EHU01683.1 - 1.9e-63 212.5 1.8 2.2e-63 212.3 1.8 1.0 1 0 0 1 1 1 1 AIR carboxylase MFMR PF07777.11 EHU01683.1 - 0.054 14.0 0.2 14 6.3 0.0 2.2 1 1 1 2 2 2 0 G-box binding protein MFMR ATP-grasp PF02222.22 EHU01684.1 - 3.8e-53 179.6 0.0 5.1e-53 179.2 0.0 1.1 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 EHU01684.1 - 2.6e-16 59.1 0.0 5.5e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain FtsX PF02687.21 EHU01685.1 - 9.8e-09 35.6 12.4 1.7e-05 25.2 0.4 5.8 6 1 0 6 6 6 2 FtsX-like permease family MacB_PCD PF12704.7 EHU01685.1 - 0.0057 17.0 2.2 0.013 15.9 0.0 2.5 2 0 0 2 2 2 1 MacB-like periplasmic core domain Lipase_GDSL_2 PF13472.6 EHU01686.1 - 8.7e-26 91.4 0.0 1.1e-25 91.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EHU01686.1 - 1.5e-14 54.5 0.0 1.7e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 EHU01686.1 - 0.00012 22.3 0.0 0.00032 20.9 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF3263 PF11662.8 EHU01686.1 - 0.031 14.1 0.0 0.075 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3263) OSK PF17182.4 EHU01686.1 - 0.089 12.0 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 OSK domain adh_short PF00106.25 EHU01687.1 - 1.1e-40 139.2 0.0 1.3e-40 139.0 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EHU01687.1 - 1.5e-29 103.2 0.0 1.9e-29 102.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EHU01687.1 - 5.8e-11 42.6 0.0 8.7e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EHU01687.1 - 3.6e-05 23.7 0.0 6e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 EHU01687.1 - 0.00017 21.1 0.0 0.00042 19.8 0.0 1.6 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EHU01687.1 - 0.00023 20.7 0.1 0.0029 17.1 0.0 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 EHU01687.1 - 0.14 11.9 0.1 0.29 10.9 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.13 EHU01687.1 - 0.19 11.3 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family GDP_Man_Dehyd PF16363.5 EHU01687.1 - 0.23 10.8 0.0 0.58 9.5 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase TPR_20 PF14561.6 EHU01688.1 - 2.3e-29 101.6 12.0 3.2e-29 101.1 4.5 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat Thioredoxin PF00085.20 EHU01688.1 - 1.9e-19 69.6 0.0 3.4e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin TPR_19 PF14559.6 EHU01688.1 - 2.2e-18 66.5 14.3 5.9e-18 65.1 0.3 3.8 3 1 1 4 4 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EHU01688.1 - 3.9e-06 27.0 0.1 4.6e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 OST3_OST6 PF04756.13 EHU01688.1 - 2e-05 24.1 0.0 2.7e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family TraF PF13728.6 EHU01688.1 - 4.1e-05 23.5 0.0 0.0001 22.2 0.0 1.6 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 EHU01688.1 - 7.2e-05 23.0 0.0 0.0052 17.1 0.0 2.6 2 1 1 3 3 2 1 Thioredoxin-like Thioredoxin_6 PF13848.6 EHU01688.1 - 0.00029 20.8 0.0 0.00058 19.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain TPR_14 PF13428.6 EHU01688.1 - 0.00065 20.3 12.3 0.82 10.7 0.3 5.9 1 1 5 6 6 6 2 Tetratricopeptide repeat Thioredoxin_2 PF13098.6 EHU01688.1 - 0.0024 18.3 0.0 0.006 17.0 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain TPR_16 PF13432.6 EHU01688.1 - 0.0028 18.2 2.1 0.94 10.2 0.0 3.9 4 1 0 4 4 4 1 Tetratricopeptide repeat SPO22 PF08631.10 EHU01688.1 - 0.0095 15.4 0.6 0.014 14.9 0.6 1.3 1 0 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like TPR_17 PF13431.6 EHU01688.1 - 0.014 15.7 0.0 1.1 9.8 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Vps39_1 PF10366.9 EHU01688.1 - 0.018 15.3 2.1 0.84 9.9 0.1 2.8 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 ChAPs PF09295.10 EHU01688.1 - 0.022 13.8 0.4 0.031 13.3 0.4 1.3 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) Syntaxin_2 PF14523.6 EHU01688.1 - 0.034 14.5 0.7 0.07 13.5 0.7 1.6 1 0 0 1 1 1 0 Syntaxin-like protein Thioredoxin_7 PF13899.6 EHU01688.1 - 0.049 13.8 0.1 0.29 11.3 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like Acetyltransf_6 PF13480.7 EHU01688.1 - 0.062 13.4 0.4 0.5 10.5 0.0 2.4 2 1 1 3 3 3 0 Acetyltransferase (GNAT) domain BTAD PF03704.17 EHU01688.1 - 0.096 13.1 5.8 1.1 9.6 1.0 2.7 1 1 0 2 2 2 0 Bacterial transcriptional activator domain SRP_TPR_like PF17004.5 EHU01688.1 - 0.12 12.5 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Putative TPR-like repeat Pkinase PF00069.25 EHU01688.1 - 0.15 11.4 0.0 0.36 10.1 0.0 1.5 2 0 0 2 2 2 0 Protein kinase domain TPR_4 PF07721.14 EHU01688.1 - 0.61 10.9 0.0 0.61 10.9 0.0 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EHU01688.1 - 6 6.9 7.5 46 4.1 0.1 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Band_7 PF01145.25 EHU01689.1 - 6.4e-30 104.5 9.5 1e-28 100.6 9.5 2.1 1 1 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 EHU01689.1 - 6.1e-07 29.4 0.4 1e-06 28.7 0.4 1.4 1 0 0 1 1 1 1 C-terminal region of band_7 Band_7_1 PF13421.6 EHU01689.1 - 0.046 13.4 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 SPFH domain-Band 7 family Flot PF15975.5 EHU01689.1 - 2.2 8.5 14.1 0.11 12.7 5.8 2.5 1 1 2 3 3 3 0 Flotillin NfeD PF01957.18 EHU01690.1 - 2e-17 63.3 0.8 2.9e-17 62.8 0.0 1.6 2 0 0 2 2 2 1 NfeD-like C-terminal, partner-binding Phage_holin_3_6 PF07332.11 EHU01690.1 - 0.0018 18.3 3.6 0.0028 17.7 3.6 1.3 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III DUF4131 PF13567.6 EHU01690.1 - 2.5 7.7 7.5 4.3 7.0 7.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) MerR_1 PF13411.6 EHU01691.1 - 4.1e-18 65.2 0.1 9.1e-18 64.1 0.0 1.6 2 0 0 2 2 2 1 MerR HTH family regulatory protein MerR-DNA-bind PF09278.11 EHU01691.1 - 2.8e-16 59.8 5.1 4.7e-16 59.1 4.5 1.6 2 0 0 2 2 2 1 MerR, DNA binding MerR PF00376.23 EHU01691.1 - 1.9e-14 53.1 0.1 1.3e-13 50.4 0.1 2.2 3 0 0 3 3 3 1 MerR family regulatory protein Phage_integrase PF00589.22 EHU01693.1 - 4e-22 78.8 0.7 3.8e-21 75.6 0.7 2.2 1 1 0 1 1 1 1 Phage integrase family Arm-DNA-bind_4 PF14657.6 EHU01693.1 - 0.0057 16.4 0.3 0.012 15.3 0.3 1.5 1 0 0 1 1 1 1 Arm DNA-binding domain Phage_int_SAM_4 PF13495.6 EHU01693.1 - 0.02 15.3 0.0 0.056 13.9 0.0 1.8 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain DUF2724 PF10893.8 EHU01695.1 - 7.2e-29 99.4 0.1 7.9e-29 99.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2724) TGS PF02824.21 EHU01696.1 - 0.082 13.0 0.1 0.21 11.7 0.0 1.6 2 0 0 2 2 2 0 TGS domain MethyltransfD12 PF02086.15 EHU01698.1 - 2.2e-60 204.5 0.0 2.5e-60 204.4 0.0 1.0 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Dam PF05869.11 EHU01698.1 - 0.062 12.9 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 DNA N-6-adenine-methyltransferase (Dam) Phage_GPA PF05840.13 EHU01700.1 - 6.4e-98 327.8 0.1 1.1e-97 326.9 0.1 1.4 1 0 0 1 1 1 1 Bacteriophage replication gene A protein (GPA) PhdYeFM_antitox PF02604.19 EHU01702.1 - 2.7e-15 55.9 0.0 3e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Antitoxin Phd_YefM, type II toxin-antitoxin system KH_4 PF13083.6 EHU01702.1 - 0.048 13.5 0.0 0.1 12.5 0.0 1.5 2 0 0 2 2 2 0 KH domain HTH_17 PF12728.7 EHU01702.1 - 0.15 12.2 0.0 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Fic PF02661.18 EHU01703.1 - 8.3e-09 36.2 0.3 2.8e-08 34.5 0.3 1.8 1 1 0 1 1 1 1 Fic/DOC family Ntox33 PF15533.6 EHU01703.1 - 0.007 16.8 0.0 2.7 8.5 0.0 2.4 1 1 1 2 2 2 2 Bacterial toxin 33 Phage_portal PF04860.12 EHU01704.1 - 2.5e-14 53.2 0.0 3.1e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Phage portal protein Terminase_6 PF03237.15 EHU01705.1 - 6.1e-52 176.4 0.4 9.7e-52 175.7 0.4 1.3 1 0 0 1 1 1 1 Terminase-like family Terminase_6C PF17289.2 EHU01705.1 - 3.2e-28 98.8 0.0 5.9e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 Terminase RNaseH-like domain Terminase_5 PF06056.12 EHU01705.1 - 1.5e-26 92.0 0.8 3e-26 91.1 0.8 1.5 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) HTH_23 PF13384.6 EHU01705.1 - 1.2e-07 31.4 1.4 3.1e-07 30.0 0.0 2.4 3 0 0 3 3 2 1 Homeodomain-like domain HTH_28 PF13518.6 EHU01705.1 - 3.4e-06 27.1 0.2 9.2e-06 25.7 0.2 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 EHU01705.1 - 0.00053 20.2 0.4 0.0014 18.9 0.1 1.9 2 0 0 2 2 2 1 Transposase Sigma70_r4_2 PF08281.12 EHU01705.1 - 0.00077 19.1 0.0 0.0021 17.7 0.0 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 EHU01705.1 - 0.002 17.8 0.0 0.005 16.6 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_17 PF12728.7 EHU01705.1 - 0.0043 17.2 0.1 1.4 9.1 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain Phage_terminase PF10668.9 EHU01705.1 - 0.0052 16.8 1.8 0.0061 16.5 0.0 2.0 2 0 0 2 2 2 1 Phage terminase small subunit HTH_29 PF13551.6 EHU01705.1 - 0.0056 16.7 0.1 0.031 14.3 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_1_2 PF13022.6 EHU01705.1 - 0.0072 16.5 0.0 0.022 14.9 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix of insertion element transposase DUF86 PF01934.17 EHU01705.1 - 0.011 15.6 0.0 0.034 14.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function DUF86 HTH_7 PF02796.15 EHU01705.1 - 0.019 15.0 0.2 0.36 11.0 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase DUF1323 PF07037.11 EHU01705.1 - 0.067 13.6 0.0 0.2 12.1 0.0 1.8 2 0 0 2 2 2 0 Putative transcription regulator (DUF1323) DUF1804 PF08822.11 EHU01705.1 - 0.11 12.5 0.1 0.24 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) Phage_GPO PF05929.11 EHU01706.1 - 1.5e-90 303.6 0.2 1.6e-90 303.4 0.2 1.0 1 0 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase DUF4061 PF13270.6 EHU01706.1 - 0.0011 19.2 0.2 0.0078 16.5 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4061) T7SS_ESX_EspC PF10824.8 EHU01706.1 - 0.18 12.3 2.2 1.3 9.5 0.6 2.6 2 1 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm Phage_cap_P2 PF05125.12 EHU01707.1 - 8.7e-116 386.5 0.1 9.9e-116 386.3 0.1 1.0 1 0 0 1 1 1 1 Phage major capsid protein, P2 family Phage_term_smal PF05944.12 EHU01708.1 - 1.3e-39 135.1 0.0 2.4e-39 134.3 0.0 1.5 1 0 0 1 1 1 1 Phage small terminase subunit Phage_GPL PF05926.11 EHU01709.1 - 1.5e-41 141.7 0.1 2.4e-41 141.0 0.1 1.3 1 1 0 1 1 1 1 Phage head completion protein (GPL) Acylphosphatase PF00708.18 EHU01709.1 - 0.19 12.1 0.0 0.31 11.5 0.0 1.3 1 0 0 1 1 1 0 Acylphosphatase Phage_tail_X PF05489.12 EHU01710.1 - 4.1e-22 77.6 0.0 4.8e-22 77.4 0.0 1.0 1 0 0 1 1 1 1 Phage Tail Protein X LysM PF01476.20 EHU01710.1 - 0.0021 18.1 0.0 0.0029 17.6 0.0 1.2 1 0 0 1 1 1 1 LysM domain Phage_holin_2_3 PF16080.5 EHU01711.1 - 0.00018 21.2 0.1 0.00027 20.6 0.1 1.3 1 0 0 1 1 1 1 Bacteriophage holin family HP1 Phage_holin_2_4 PF16082.5 EHU01711.1 - 0.00093 18.9 0.9 0.0013 18.5 0.7 1.3 1 1 0 1 1 1 1 Bacteriophage holin family, superfamily II-like tRNA-synt_1b PF00579.25 EHU01711.1 - 0.024 14.0 0.0 0.03 13.7 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) DUF1430 PF07242.11 EHU01711.1 - 0.11 12.8 0.1 0.13 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1430) DUF4646 PF15496.6 EHU01711.1 - 0.17 12.5 0.0 0.22 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) Phage_lysozyme PF00959.19 EHU01712.1 - 5.4e-14 52.6 1.9 2.4e-13 50.5 1.9 1.8 1 1 0 1 1 1 1 Phage lysozyme DUF2570 PF10828.8 EHU01713.1 - 0.00029 20.6 0.2 0.00042 20.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2570) DUF4131 PF13567.6 EHU01713.1 - 0.0048 16.6 0.0 0.0064 16.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) TarH PF02203.15 EHU01713.1 - 0.02 14.9 0.3 0.02 14.9 0.3 1.4 2 0 0 2 2 2 0 Tar ligand binding domain homologue DUF4307 PF14155.6 EHU01713.1 - 0.046 13.5 0.1 0.061 13.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) MAT1 PF06391.13 EHU01713.1 - 0.063 13.1 1.3 0.075 12.8 1.3 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 FliS_cochap PF16522.5 EHU01713.1 - 0.066 13.2 0.1 0.091 12.7 0.1 1.1 1 0 0 1 1 1 0 Flagellar FLiS export co-chaperone, HP1076 P2_Phage_GpR PF06891.11 EHU01714.1 - 2.9e-34 118.0 0.0 3.3e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 P2 phage tail completion protein R (GpR) Phage_tail_S PF05069.13 EHU01715.1 - 9.2e-26 90.5 2.1 3.3e-13 49.7 0.0 2.1 2 0 0 2 2 2 2 Phage virion morphogenesis family DUF3947 PF13135.6 EHU01715.1 - 0.27 11.5 1.6 3 8.1 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3947) Phage_base_V PF04717.12 EHU01716.1 - 6e-36 122.8 0.0 8.2e-36 122.3 0.0 1.2 1 0 0 1 1 1 1 Type VI secretion system, phage-baseplate injector Phage_spike PF18715.1 EHU01716.1 - 1.4e-23 82.7 1.4 2.4e-23 81.9 1.4 1.4 1 0 0 1 1 1 1 Phage spike trimer GPW_gp25 PF04965.14 EHU01717.1 - 2e-09 37.1 0.0 2.4e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Gene 25-like lysozyme Baseplate_J PF04865.14 EHU01718.1 - 2e-24 86.1 2.6 2.7e-24 85.7 1.0 1.9 1 1 1 2 2 2 1 Baseplate J-like protein AIRS_C PF02769.22 EHU01718.1 - 0.029 14.5 1.3 0.046 13.9 0.3 1.8 2 0 0 2 2 2 0 AIR synthase related protein, C-terminal domain Tail_P2_I PF09684.10 EHU01719.1 - 2.2e-52 176.6 0.1 2.7e-52 176.3 0.1 1.1 1 0 0 1 1 1 1 Phage tail protein (Tail_P2_I) DUF3751 PF12571.8 EHU01720.1 - 9.5e-65 217.3 0.3 1.5e-64 216.6 0.3 1.3 1 0 0 1 1 1 1 Phage tail-collar fibre protein Phage_P2_GpU PF06995.11 EHU01721.1 - 1.4e-38 131.2 0.0 1.7e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Phage P2 GpU PhageMin_Tail PF10145.9 EHU01722.1 - 7.6e-49 166.3 13.2 7.6e-49 166.3 13.2 4.4 3 2 1 4 4 4 1 Phage-related minor tail protein LXG PF04740.12 EHU01722.1 - 0.0016 18.2 2.8 0.0016 18.2 2.8 2.8 4 0 0 4 4 4 1 LXG domain of WXG superfamily RPW8 PF05659.11 EHU01722.1 - 0.087 12.5 0.0 8.9 6.0 0.1 3.4 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 PI3K_P85_iSH2 PF16454.5 EHU01722.1 - 0.15 11.7 6.6 0.46 10.1 6.6 1.9 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain V_ATPase_I PF01496.19 EHU01722.1 - 0.31 8.9 2.4 0.49 8.3 2.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Baculo_PEP_C PF04513.12 EHU01722.1 - 0.37 10.8 8.6 0.99 9.4 0.4 4.2 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus FapA PF03961.13 EHU01722.1 - 0.43 9.1 5.2 2.5 6.6 2.6 2.4 2 0 0 2 2 2 0 Flagellar Assembly Protein A Vps53_N PF04100.12 EHU01722.1 - 0.48 9.3 6.0 2.6 6.9 2.7 2.4 2 0 0 2 2 2 0 Vps53-like, N-terminal NPV_P10 PF05531.12 EHU01722.1 - 0.59 10.6 11.9 11 6.6 0.1 5.3 4 1 2 6 6 6 0 Nucleopolyhedrovirus P10 protein V-SNARE_C PF12352.8 EHU01722.1 - 0.61 10.4 5.9 0.19 12.0 0.8 2.7 3 0 0 3 3 2 0 Snare region anchored in the vesicle membrane C-terminus Sec8_exocyst PF04048.14 EHU01722.1 - 0.81 9.6 4.0 6.2 6.7 0.6 3.3 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain FAM184 PF15665.5 EHU01722.1 - 1 9.1 15.5 0.27 11.0 6.8 3.0 2 1 1 3 3 3 0 Family with sequence similarity 184, A and B MscS_porin PF12795.7 EHU01722.1 - 1.2 8.6 26.0 0.23 11.0 21.4 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Golgin_A5 PF09787.9 EHU01722.1 - 1.7 8.0 12.4 4.3 6.7 12.4 1.6 1 0 0 1 1 1 0 Golgin subfamily A member 5 TMPIT PF07851.13 EHU01722.1 - 9.9 5.3 5.3 9.2 5.4 0.2 2.1 1 1 1 2 2 2 0 TMPIT-like protein Phage_TAC_7 PF10109.9 EHU01723.1 - 1.7e-06 28.1 0.3 2.3e-06 27.6 0.3 1.2 1 0 0 1 1 1 1 Phage tail assembly chaperone proteins, E, or 41 or 14 Phage_tube PF04985.14 EHU01724.1 - 5.9e-50 169.2 0.0 6.4e-50 169.1 0.0 1.0 1 0 0 1 1 1 1 Phage tail tube protein FII Phage_sheath_1 PF04984.14 EHU01725.1 - 1e-23 84.0 0.4 1.8e-23 83.2 0.1 1.5 2 0 0 2 2 2 1 Phage tail sheath protein subtilisin-like domain Phage_sheath_1C PF17482.2 EHU01725.1 - 6.1e-09 35.8 0.0 1.1e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Phage tail sheath C-terminal domain DUF2482 PF10655.9 EHU01725.1 - 0.074 13.6 0.0 2.5 8.7 0.0 2.8 3 0 0 3 3 3 0 Hypothetical protein of unknown function (DUF2482) Phage_GPD PF05954.11 EHU01726.1 - 1.9e-25 89.8 0.1 2.3e-25 89.5 0.1 1.1 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) Ogr_Delta PF04606.12 EHU01727.1 - 1.1e-09 38.2 2.9 1.3e-09 37.9 2.9 1.1 1 0 0 1 1 1 1 Ogr/Delta-like zinc finger E1-E2_ATPase PF00122.20 EHU01728.1 - 5.7e-52 175.9 2.2 5.6e-51 172.6 1.4 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EHU01728.1 - 1.7e-48 165.7 2.7 1.7e-48 165.7 2.7 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EHU01728.1 - 2.4e-25 88.7 1.9 9.6e-14 51.6 0.1 2.4 2 0 0 2 2 2 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EHU01728.1 - 4.2e-09 36.5 0.4 9.8e-07 28.8 0.4 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EHU01728.1 - 1.8e-08 35.0 0.3 2e-07 31.6 0.1 2.8 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF3040 PF11239.8 EHU01728.1 - 0.022 15.0 1.7 0.022 15.0 1.7 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Hydrolase_6 PF13344.6 EHU01728.1 - 0.031 14.4 0.0 0.26 11.4 0.0 2.7 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase CBS PF00571.28 EHU01728.1 - 0.047 14.1 0.0 0.21 12.0 0.0 2.1 1 1 1 2 2 2 0 CBS domain HAD_2 PF13419.6 EHU01728.1 - 0.088 12.9 0.0 0.33 11.0 0.0 1.8 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase TraB PF01963.17 EHU01729.1 - 3.5e-39 135.3 0.0 4.6e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 TraB family RHH_1 PF01402.21 EHU01729.1 - 0.023 14.6 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family Hydrolase_4 PF12146.8 EHU01729.1 - 0.034 13.4 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF2271 PF10029.9 EHU01729.1 - 0.07 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2271) tRNA_edit PF04073.15 EHU01730.1 - 1.5e-25 89.6 0.1 1.9e-25 89.3 0.1 1.1 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain LysR_substrate PF03466.20 EHU01731.1 - 8e-26 90.7 5.6 2.2e-25 89.3 5.6 1.7 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EHU01731.1 - 1.9e-17 62.9 0.1 4.4e-17 61.8 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family NUMOD1 PF07453.13 EHU01731.1 - 0.26 11.6 0.1 0.42 10.9 0.1 1.3 1 0 0 1 1 1 0 NUMOD1 domain BTP PF05232.12 EHU01732.1 - 9.5e-50 166.5 13.8 3.4e-26 91.1 1.0 2.0 2 0 0 2 2 2 2 Chlorhexidine efflux transporter 5_nucleotid_C PF02872.18 EHU01733.1 - 1.7e-36 125.8 0.2 3.5e-36 124.8 0.2 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EHU01733.1 - 4.3e-16 60.0 0.1 1.3e-15 58.4 0.1 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase PGA_cap PF09587.10 EHU01733.1 - 0.023 14.2 0.0 0.053 13.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap Na_H_Exchanger PF00999.21 EHU01734.1 - 3.2e-79 266.5 49.6 4.4e-79 266.0 49.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 EHU01734.1 - 7.4e-20 71.3 1.9 7.4e-20 71.3 1.9 1.7 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_2 PF03446.15 EHU01734.1 - 0.025 14.7 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 EHU01734.1 - 0.1 12.3 0.1 0.24 11.1 0.1 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 EHU01734.1 - 0.14 12.3 0.1 0.14 12.3 0.1 2.0 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EHU01734.1 - 0.19 12.2 0.3 0.59 10.6 0.1 1.9 1 1 1 2 2 2 0 Putative NAD(P)-binding PfkB PF00294.24 EHU01735.1 - 5e-13 49.0 0.0 3.3e-08 33.2 0.0 2.3 2 0 0 2 2 2 2 pfkB family carbohydrate kinase ADK PF00406.22 EHU01736.1 - 2e-60 203.2 0.1 2.4e-60 203.0 0.1 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EHU01736.1 - 5e-27 95.0 0.4 1e-26 94.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 EHU01736.1 - 4.1e-16 58.7 0.0 7.4e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid Hydin_ADK PF17213.3 EHU01736.1 - 0.00012 22.4 2.3 0.37 11.1 0.0 2.6 2 1 1 3 3 3 2 Hydin Adenylate kinase-like domain AAA_33 PF13671.6 EHU01736.1 - 0.0014 18.8 0.1 0.0091 16.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EHU01736.1 - 0.0033 18.0 0.0 0.0061 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EHU01736.1 - 0.025 14.8 0.0 0.043 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 EHU01736.1 - 0.15 11.7 0.5 0.9 9.2 0.1 2.1 2 0 0 2 2 2 0 Thymidylate kinase HSP90 PF00183.18 EHU01737.1 - 1.1e-130 437.0 5.0 2.4e-128 429.3 5.6 2.0 1 1 1 2 2 2 2 Hsp90 protein HATPase_c PF02518.26 EHU01737.1 - 9.1e-14 51.9 0.1 1.8e-13 51.0 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EHU01737.1 - 3.7e-11 43.0 1.6 4.4e-11 42.7 0.2 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AnfO_nitrog PF09582.10 EHU01737.1 - 0.077 12.3 0.1 0.17 11.2 0.1 1.5 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) Toprim_4 PF13662.6 EHU01738.1 - 4.9e-24 84.6 0.0 8.2e-24 83.9 0.0 1.4 1 0 0 1 1 1 1 Toprim domain RecR PF02132.15 EHU01738.1 - 1.7e-15 56.3 1.4 3.3e-15 55.4 1.4 1.5 1 0 0 1 1 1 1 RecR protein Toprim PF01751.22 EHU01738.1 - 2.2e-11 43.9 0.0 3.7e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Toprim domain HHH PF00633.23 EHU01738.1 - 0.026 14.4 0.4 0.22 11.5 0.0 2.5 3 0 0 3 3 3 0 Helix-hairpin-helix motif HHH_5 PF14520.6 EHU01738.1 - 0.042 14.5 0.0 0.38 11.4 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix domain FYVE_2 PF02318.16 EHU01738.1 - 0.056 13.7 0.5 0.99 9.6 0.3 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger Gln-synt_N_2 PF16952.5 EHU01738.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Glutamine synthetase N-terminal domain Toprim_2 PF13155.6 EHU01738.1 - 0.15 12.5 0.0 0.65 10.5 0.0 1.9 2 0 0 2 2 2 0 Toprim-like YbaB_DNA_bd PF02575.16 EHU01739.1 - 3.9e-33 113.6 8.0 4.4e-33 113.4 8.0 1.0 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family IIGP PF05049.13 EHU01739.1 - 0.021 13.9 0.2 0.029 13.4 0.2 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) CARM1 PF11531.8 EHU01739.1 - 0.08 13.1 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Coactivator-associated arginine methyltransferase 1 N terminal DNA_pol3_tau_5 PF12170.8 EHU01740.1 - 2e-56 190.0 5.0 4.7e-56 188.8 5.0 1.7 1 0 0 1 1 1 1 DNA polymerase III tau subunit V interacting with alpha DNA_pol3_delta2 PF13177.6 EHU01740.1 - 7.7e-43 146.1 0.0 1.1e-42 145.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DNA_pol3_gamma3 PF12169.8 EHU01740.1 - 1.8e-34 118.7 2.5 1.8e-34 118.7 2.5 2.8 3 0 0 3 3 3 1 DNA polymerase III subunits gamma and tau domain III DNA_pol3_tau_4 PF12168.8 EHU01740.1 - 7.4e-19 68.1 9.9 7.4e-19 68.1 9.9 2.8 3 0 0 3 3 2 1 DNA polymerase III subunits tau domain IV DnaB-binding AAA PF00004.29 EHU01740.1 - 9.2e-12 45.5 0.0 2.5e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EHU01740.1 - 1.9e-06 27.7 0.0 9e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EHU01740.1 - 3.3e-06 27.4 0.2 2.2e-05 24.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EHU01740.1 - 9.6e-06 25.6 0.0 2.5e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EHU01740.1 - 0.00034 21.2 0.0 0.0008 20.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EHU01740.1 - 0.00043 20.1 0.0 0.0019 17.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EHU01740.1 - 0.00072 19.6 0.1 0.2 11.7 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 EHU01740.1 - 0.00083 19.8 0.2 0.00083 19.8 0.2 4.3 1 1 1 2 2 1 1 AAA ATPase domain DNA_pol3_delta PF06144.13 EHU01740.1 - 0.0011 18.8 0.1 0.0021 17.9 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 EHU01740.1 - 0.0011 19.0 0.0 0.003 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EHU01740.1 - 0.007 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 EHU01740.1 - 0.011 15.0 0.2 0.97 8.6 0.0 2.2 1 1 1 2 2 2 0 TIP49 P-loop domain TsaE PF02367.17 EHU01740.1 - 0.03 14.3 0.1 0.074 13.1 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EHU01740.1 - 0.031 13.8 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_assoc_2 PF16193.5 EHU01740.1 - 0.067 13.5 0.7 0.24 11.7 0.1 2.4 2 0 0 2 2 1 0 AAA C-terminal domain Mg_chelatase PF01078.21 EHU01740.1 - 0.077 12.4 0.1 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SKI PF01202.22 EHU01740.1 - 0.098 12.8 0.1 0.36 10.9 0.1 2.0 1 0 0 1 1 1 0 Shikimate kinase AAA_19 PF13245.6 EHU01740.1 - 1.5 9.1 3.7 2.5 8.4 0.2 3.0 3 1 0 3 3 3 0 AAA domain Nif11 PF07862.11 EHU01740.1 - 2.1 8.7 5.2 91 3.5 0.0 4.0 3 0 0 3 3 3 0 Nif11 domain Pribosyltran PF00156.27 EHU01741.1 - 2e-14 53.4 0.0 2.4e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EHU01741.1 - 0.00076 19.0 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 EHU01741.1 - 0.017 14.7 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase DUF454 PF04304.13 EHU01742.1 - 1.4e-41 141.1 14.9 1.6e-41 140.9 14.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF454) DUF308 PF03729.13 EHU01742.1 - 0.051 13.9 4.5 0.051 13.9 4.5 2.3 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) SulA PF03846.14 EHU01742.1 - 0.068 13.1 0.4 0.11 12.5 0.4 1.4 1 0 0 1 1 1 0 Cell division inhibitor SulA PRA1 PF03208.19 EHU01742.1 - 0.28 10.8 6.7 0.37 10.4 6.7 1.1 1 0 0 1 1 1 0 PRA1 family protein PriC PF07445.12 EHU01743.1 - 1.8e-38 132.2 14.6 2.2e-38 131.9 14.6 1.0 1 0 0 1 1 1 1 Primosomal replication protein priC U3_assoc_6 PF08640.11 EHU01743.1 - 0.0034 17.4 2.7 0.0034 17.4 2.7 2.0 2 1 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 Toxin-JAB1 PF15659.6 EHU01743.1 - 0.087 13.2 0.1 0.65 10.4 0.2 2.1 2 0 0 2 2 2 0 JAB-like toxin 1 DUF2496 PF10689.9 EHU01744.1 - 3.8e-22 77.8 1.0 4.4e-22 77.6 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2496) MbeD_MobD PF04899.12 EHU01744.1 - 0.055 13.6 0.1 0.08 13.1 0.1 1.4 1 1 0 1 1 1 0 MbeD/MobD like TetR_C_2 PF08361.11 EHU01745.1 - 2.7e-44 150.2 0.2 3.7e-44 149.7 0.2 1.2 1 0 0 1 1 1 1 MAATS-type transcriptional repressor, C-terminal region TetR_N PF00440.23 EHU01745.1 - 2.7e-19 68.7 0.3 4.5e-19 68.0 0.3 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 EHU01745.1 - 0.00051 20.2 0.9 0.00071 19.8 0.1 1.6 2 0 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal TetR_C_11 PF16859.5 EHU01745.1 - 0.0013 19.0 0.9 0.01 16.1 0.9 2.2 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_17 PF17922.1 EHU01745.1 - 0.004 17.2 0.0 0.19 11.9 0.0 2.3 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_33 PF13305.6 EHU01745.1 - 0.01 16.6 0.3 0.027 15.2 0.0 1.8 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain TetR_C_4 PF08359.11 EHU01745.1 - 0.053 13.7 0.0 0.084 13.0 0.0 1.3 1 0 0 1 1 1 0 YsiA-like protein, C-terminal region TetR_C_24 PF17932.1 EHU01745.1 - 0.096 13.0 0.1 0.21 11.9 0.1 1.7 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain SUV3_C PF12513.8 EHU01745.1 - 0.097 12.6 0.0 14 5.7 0.0 2.7 2 0 0 2 2 2 0 Mitochondrial degradasome RNA helicase subunit C terminal UPF0122 PF04297.14 EHU01745.1 - 0.1 12.8 0.1 0.89 9.8 0.0 2.1 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like HlyD PF00529.20 EHU01746.1 - 2.1e-15 56.4 0.3 3.3e-15 55.7 0.3 1.4 1 0 0 1 1 1 1 HlyD membrane-fusion protein of T1SS HlyD_D23 PF16576.5 EHU01746.1 - 8.3e-14 51.3 2.0 3.9e-13 49.1 2.0 2.1 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 EHU01746.1 - 4.3e-11 43.5 1.4 8.1e-08 32.9 0.1 3.0 2 1 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 EHU01746.1 - 4.8e-10 39.1 6.8 3.2e-06 26.9 0.0 3.9 3 1 1 4 4 4 2 Biotin-lipoyl like DUF3324 PF11797.8 EHU01746.1 - 0.031 14.2 1.2 0.57 10.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function C-terminal (DUF3324) ACR_tran PF00873.19 EHU01747.1 - 0 1411.1 12.0 0 1410.9 12.0 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 EHU01747.1 - 7.8e-08 31.6 33.1 1.6e-06 27.3 11.9 2.6 3 0 0 3 3 3 2 MMPL family SecD_SecF PF02355.16 EHU01747.1 - 8.4e-07 28.6 26.1 3.9e-05 23.1 4.3 2.4 2 0 0 2 2 2 2 Protein export membrane protein Ribosomal_L31 PF01197.18 EHU01748.1 - 2.8e-21 75.5 0.3 3.4e-21 75.2 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L31 Ribosomal_L36 PF00444.18 EHU01749.1 - 7.7e-16 58.0 7.1 1e-15 57.6 7.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 ZnuA PF01297.17 EHU01750.1 - 3.8e-78 262.4 0.0 4.3e-78 262.3 0.0 1.0 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic ABC-3 PF00950.17 EHU01751.1 - 5.8e-49 166.9 30.2 6.6e-49 166.7 30.2 1.0 1 0 0 1 1 1 1 ABC 3 transport family P19Arf_N PF07392.12 EHU01751.1 - 0.1 13.1 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus ABC_tran PF00005.27 EHU01752.1 - 1.3e-25 90.5 0.0 2e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EHU01752.1 - 7.6e-10 39.1 2.2 6.9e-06 26.1 0.7 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EHU01752.1 - 1.2e-08 34.7 0.8 0.0019 17.7 0.0 2.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EHU01752.1 - 5.6e-06 26.0 0.3 1.1e-05 25.0 0.3 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EHU01752.1 - 0.00038 20.9 1.0 0.0011 19.3 1.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EHU01752.1 - 0.0015 18.8 0.1 0.0047 17.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 EHU01752.1 - 0.0027 17.9 0.0 0.021 15.1 0.0 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Mg_chelatase PF01078.21 EHU01752.1 - 0.0029 17.0 0.1 0.0066 15.8 0.1 1.5 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 EHU01752.1 - 0.0038 17.8 0.0 0.006 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EHU01752.1 - 0.004 16.9 0.1 0.0054 16.5 0.1 1.1 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EHU01752.1 - 0.0056 16.6 0.1 0.0097 15.8 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_33 PF13671.6 EHU01752.1 - 0.022 14.9 0.0 0.034 14.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EHU01752.1 - 0.028 14.3 0.5 0.12 12.3 0.1 1.9 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.14 EHU01752.1 - 0.078 13.0 0.1 0.66 10.0 0.0 2.1 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 EHU01752.1 - 0.1 12.7 0.0 0.25 11.5 0.0 1.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 EHU01752.1 - 0.13 11.9 1.9 0.3 10.8 0.5 1.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EHU01752.1 - 0.14 11.7 0.3 0.36 10.4 0.2 1.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EHU01752.1 - 0.16 12.2 0.1 0.33 11.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain MukB PF04310.12 EHU01752.1 - 0.16 11.8 0.2 0.3 10.9 0.2 1.4 1 0 0 1 1 1 0 MukB N-terminal DDE_3 PF13358.6 EHU01755.1 - 1.1e-22 80.3 0.0 1.9e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 EHU01755.1 - 1.1e-10 41.0 1.0 3.6e-09 36.2 0.1 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 EHU01755.1 - 4.1e-09 36.9 1.1 2.8e-08 34.3 0.3 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 EHU01755.1 - 4e-07 30.0 1.2 1.1e-06 28.6 0.3 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHU01755.1 - 1.4e-05 25.1 0.3 0.0002 21.4 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_33 PF13592.6 EHU01755.1 - 6e-05 22.6 5.4 8.3e-05 22.1 0.5 3.0 3 0 0 3 3 3 1 Winged helix-turn helix LZ_Tnp_IS481 PF13011.6 EHU01755.1 - 0.029 14.9 0.2 0.061 13.8 0.2 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 HTH_38 PF13936.6 EHU01755.1 - 0.052 13.3 0.6 0.16 11.8 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain YbaJ PF10757.9 EHU01756.1 - 1.9e-58 196.1 2.0 2.2e-58 195.9 2.0 1.0 1 0 0 1 1 1 1 Biofilm formation regulator YbaJ DUF3926 PF13080.6 EHU01756.1 - 0.02 14.8 0.1 0.046 13.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3926) HHA PF05321.11 EHU01757.1 - 2.2e-33 114.3 0.5 2.7e-33 114.1 0.5 1.1 1 0 0 1 1 1 1 Haemolysin expression modulating protein DNA_binding_1 PF01035.20 EHU01758.1 - 6.4e-23 80.7 0.0 6.9e-23 80.6 0.0 1.0 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain DDE_3 PF13358.6 EHU01759.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHU01759.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHU01759.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHU01759.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHU01759.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHU01759.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHU01759.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHU01759.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 YscW PF09619.10 EHU01760.1 - 2.5e-38 130.7 0.2 3.3e-38 130.3 0.2 1.2 1 0 0 1 1 1 1 Type III secretion system lipoprotein chaperone (YscW) Acyl_CoA_thio PF02551.15 EHU01761.1 - 5.1e-64 214.0 0.1 4.8e-47 159.1 0.0 3.1 2 1 0 2 2 2 2 Acyl-CoA thioesterase 4HBT_3 PF13622.6 EHU01761.1 - 1.6e-58 198.9 0.1 2e-58 198.6 0.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 EHU01761.1 - 0.00022 21.5 0.0 0.00057 20.2 0.0 1.7 2 0 0 2 2 2 1 Thioesterase superfamily Ammonium_transp PF00909.21 EHU01762.1 - 2.9e-126 421.4 41.0 3.3e-126 421.2 41.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF3188 PF11384.8 EHU01762.1 - 2.7 7.7 6.4 1.8 8.3 0.1 3.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3188) P-II PF00543.22 EHU01763.1 - 1.2e-41 141.4 1.0 1.4e-41 141.2 1.0 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II DUF3240 PF11582.8 EHU01763.1 - 0.029 14.5 0.0 0.05 13.7 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3240) ABC_membrane PF00664.23 EHU01764.1 - 1.8e-41 142.6 10.8 2.5e-41 142.2 10.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EHU01764.1 - 1e-29 103.8 0.0 1.8e-29 103.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EHU01764.1 - 2.7e-08 33.5 0.1 2.6e-05 23.8 0.1 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EHU01764.1 - 8.2e-06 26.3 0.6 2e-05 25.1 0.6 1.6 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 EHU01764.1 - 0.00024 20.3 0.0 0.00041 19.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 EHU01764.1 - 0.00056 20.2 1.0 0.006 16.9 1.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EHU01764.1 - 0.0016 19.0 0.0 0.0026 18.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EHU01764.1 - 0.003 17.5 0.0 0.0059 16.5 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 EHU01764.1 - 0.0038 17.3 0.0 0.01 15.9 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 EHU01764.1 - 0.0045 16.7 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 EHU01764.1 - 0.033 14.3 0.2 0.073 13.2 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EHU01764.1 - 0.034 13.7 0.1 0.22 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EHU01764.1 - 0.038 14.1 0.0 0.072 13.1 0.0 1.5 1 0 0 1 1 1 0 Dynamin family DEAD PF00270.29 EHU01764.1 - 0.046 13.5 0.5 0.3 10.8 0.5 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase DUF87 PF01935.17 EHU01764.1 - 0.07 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain Zeta_toxin PF06414.12 EHU01764.1 - 0.076 12.3 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 EHU01764.1 - 0.18 12.4 0.0 0.46 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain YbhQ PF11076.8 EHU01764.1 - 0.86 9.6 7.7 0.053 13.5 1.1 2.4 2 1 0 2 2 2 0 Putative inner membrane protein YbhQ ABC_membrane PF00664.23 EHU01765.1 - 5.2e-38 131.3 6.5 6.4e-38 131.0 6.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EHU01765.1 - 4.4e-29 101.8 0.0 9e-29 100.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EHU01765.1 - 0.0014 18.1 0.0 0.059 12.8 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EHU01765.1 - 0.0016 18.7 0.3 0.0083 16.4 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EHU01765.1 - 0.0032 18.0 0.0 0.039 14.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EHU01765.1 - 0.0049 16.7 0.0 0.0084 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EHU01765.1 - 0.0098 16.4 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EHU01765.1 - 0.011 15.6 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase NB-ARC PF00931.22 EHU01765.1 - 0.013 14.7 0.0 0.04 13.1 0.0 1.7 1 1 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 EHU01765.1 - 0.018 14.8 0.1 0.042 13.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TMEM223 PF14640.6 EHU01765.1 - 0.064 13.4 0.1 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 Transmembrane protein 223 T2SSE PF00437.20 EHU01765.1 - 0.07 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein TsaE PF02367.17 EHU01765.1 - 0.15 12.1 0.0 0.49 10.4 0.0 1.9 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2070 PF09843.9 EHU01765.1 - 0.16 10.2 2.5 0.26 9.5 2.5 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) cobW PF02492.19 EHU01765.1 - 0.18 11.4 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AsnC_trans_reg PF01037.21 EHU01766.1 - 7.8e-21 73.8 0.0 9.9e-21 73.5 0.0 1.1 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain PALP PF00291.25 EHU01767.1 - 2e-42 145.6 0.0 2.5e-42 145.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme QueC PF06508.13 EHU01768.1 - 7.4e-83 277.2 0.0 8.5e-83 277.0 0.0 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.19 EHU01768.1 - 4e-05 23.1 0.0 6.7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Arginosuccinate synthase ThiI PF02568.14 EHU01768.1 - 0.0012 18.5 0.1 0.0051 16.4 0.1 1.9 1 1 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.21 EHU01768.1 - 0.0021 17.8 0.0 0.0033 17.1 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase PAPS_reduct PF01507.19 EHU01768.1 - 0.011 15.8 0.0 0.044 13.8 0.0 1.8 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.20 EHU01768.1 - 0.021 14.6 0.1 0.038 13.8 0.1 1.4 1 0 0 1 1 1 0 PP-loop family NAD_synthase PF02540.17 EHU01768.1 - 0.033 13.3 0.0 0.049 12.8 0.0 1.3 1 0 0 1 1 1 0 NAD synthase Diphthami_syn_2 PF01902.17 EHU01768.1 - 0.083 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Diphthamide synthase 4HBT_2 PF13279.6 EHU01769.1 - 1.4e-16 61.1 0.0 1.6e-16 60.9 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 EHU01769.1 - 3.6e-14 52.9 0.0 5.2e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 EHU01769.1 - 1.9e-12 47.0 0.1 1e-05 25.0 0.1 2.0 1 1 1 2 2 2 2 Acyl-ACP thioesterase HHH_3 PF12836.7 EHU01770.1 - 6.8e-18 64.7 0.0 8.2e-18 64.4 0.0 1.1 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 EHU01770.1 - 5.3e-05 22.9 0.0 0.0047 16.7 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 EHU01770.1 - 0.00017 22.1 0.0 0.41 11.3 0.0 2.3 2 0 0 2 2 2 2 Helix-hairpin-helix domain T2SSK PF03934.13 EHU01770.1 - 0.00022 20.7 0.0 0.00034 20.1 0.0 1.3 1 1 0 1 1 1 1 Type II secretion system (T2SS), protein K HHH_2 PF12826.7 EHU01770.1 - 0.03 14.4 0.1 0.076 13.1 0.1 1.7 1 1 1 2 2 2 0 Helix-hairpin-helix motif SurA_N_3 PF13624.6 EHU01771.1 - 6.9e-52 175.5 10.2 6.9e-52 175.5 10.2 3.2 3 0 0 3 3 3 1 SurA N-terminal domain SurA_N_2 PF13623.6 EHU01771.1 - 1.9e-34 118.6 7.6 1.9e-34 118.6 7.6 3.7 4 0 0 4 4 4 1 SurA N-terminal domain Rotamase_2 PF13145.6 EHU01771.1 - 5.7e-34 117.6 34.3 6.6e-24 85.1 0.2 5.5 3 3 2 5 5 5 4 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EHU01771.1 - 1e-15 58.3 8.9 3.3e-14 53.4 0.1 4.5 3 2 0 3 3 3 2 PPIC-type PPIASE domain Rotamase PF00639.21 EHU01771.1 - 3e-14 53.7 15.3 2.9e-13 50.6 0.1 4.8 4 0 0 4 4 4 2 PPIC-type PPIASE domain Bac_DNA_binding PF00216.21 EHU01772.1 - 2.8e-35 120.4 0.0 3.1e-35 120.3 0.0 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 EHU01772.1 - 7.4e-07 29.3 0.0 7.9e-07 29.2 0.0 1.0 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_euk_2 PF18289.1 EHU01772.1 - 0.0015 18.6 0.0 0.0022 18.1 0.0 1.1 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 HU-CCDC81_bac_2 PF18175.1 EHU01772.1 - 0.0017 18.2 0.0 0.0022 17.8 0.0 1.1 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 HU-CCDC81_euk_1 PF14908.6 EHU01772.1 - 0.059 13.5 0.0 0.061 13.5 0.0 1.1 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 1 SSPI PF14098.6 EHU01772.1 - 0.16 12.2 0.0 0.31 11.2 0.0 1.5 2 0 0 2 2 2 0 Small, acid-soluble spore protein I Lon_C PF05362.13 EHU01773.1 - 7.9e-97 322.8 0.2 1.3e-96 322.0 0.2 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 EHU01773.1 - 1.7e-42 145.7 0.5 1.7e-42 145.7 0.5 1.8 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 EHU01773.1 - 1.2e-17 64.6 0.0 2.8e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EHU01773.1 - 1.7e-10 41.1 0.0 1.3e-09 38.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 EHU01773.1 - 5.8e-07 29.4 0.0 1.7e-06 27.8 0.0 1.9 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_PrkA PF08298.11 EHU01773.1 - 5.7e-06 25.5 0.0 1.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_16 PF13191.6 EHU01773.1 - 7.6e-05 23.2 0.0 0.00042 20.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 EHU01773.1 - 0.00055 19.7 0.0 0.0015 18.3 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 EHU01773.1 - 0.002 18.0 0.0 0.0061 16.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EHU01773.1 - 0.0028 17.4 0.1 0.03 14.1 0.0 2.7 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EHU01773.1 - 0.0076 16.8 1.7 0.014 15.9 0.0 2.5 2 1 0 2 2 1 1 AAA domain AAA_22 PF13401.6 EHU01773.1 - 0.0089 16.3 0.2 0.11 12.8 0.2 2.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EHU01773.1 - 0.011 15.8 0.0 0.054 13.5 0.0 2.3 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 EHU01773.1 - 0.016 15.2 0.1 0.36 10.7 0.0 2.5 2 0 0 2 2 2 0 NACHT domain ECH_2 PF16113.5 EHU01773.1 - 0.016 14.7 3.6 0.068 12.7 1.6 2.4 3 0 0 3 3 3 0 Enoyl-CoA hydratase/isomerase Citrate_bind PF16114.5 EHU01773.1 - 0.033 13.7 0.0 0.099 12.1 0.0 1.8 1 0 0 1 1 1 0 ATP citrate lyase citrate-binding T3SSipB PF16535.5 EHU01773.1 - 0.034 14.6 2.7 0.073 13.5 2.7 1.6 1 0 0 1 1 1 0 Type III cell invasion protein SipB AAA_33 PF13671.6 EHU01773.1 - 0.035 14.3 0.4 0.13 12.4 0.1 2.1 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EHU01773.1 - 0.05 13.5 0.0 0.17 11.8 0.0 1.9 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 EHU01773.1 - 0.099 12.7 0.0 0.3 11.1 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EHU01773.1 - 0.13 12.5 0.1 2.1 8.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain Birna_VP4 PF01768.16 EHU01773.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Birnavirus VP4 protein RNA_helicase PF00910.22 EHU01773.1 - 0.13 12.7 0.0 0.54 10.7 0.0 2.1 2 0 0 2 2 1 0 RNA helicase Exonuc_VII_L PF02601.15 EHU01773.1 - 0.79 9.2 3.9 1.3 8.5 3.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit ABC_tran PF00005.27 EHU01773.1 - 1.4 9.4 3.5 2.1 8.8 0.1 2.8 2 1 0 2 2 2 0 ABC transporter Bap31_Bap29_C PF18035.1 EHU01773.1 - 1.5 8.9 6.3 18 5.4 0.4 3.1 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain AAA_2 PF07724.14 EHU01774.1 - 2.8e-48 164.2 0.0 4.7e-48 163.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) zf-C4_ClpX PF06689.13 EHU01774.1 - 6.5e-21 73.9 3.4 1.8e-20 72.5 3.4 1.8 1 0 0 1 1 1 1 ClpX C4-type zinc finger ClpB_D2-small PF10431.9 EHU01774.1 - 3.8e-17 62.1 1.9 5.9e-17 61.5 0.4 2.1 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EHU01774.1 - 1.6e-15 57.7 0.0 3.6e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EHU01774.1 - 3.6e-07 29.8 0.2 0.00011 21.7 0.2 3.1 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EHU01774.1 - 8.7e-07 29.0 0.1 8.7e-06 25.8 0.1 2.6 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EHU01774.1 - 1.8e-06 28.3 0.2 1.9e-05 24.9 0.2 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EHU01774.1 - 6.8e-06 25.9 0.1 2.2e-05 24.3 0.1 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain MCM PF00493.23 EHU01774.1 - 9.2e-06 24.9 0.0 1.5e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain AAA_16 PF13191.6 EHU01774.1 - 0.0004 20.8 0.2 0.0013 19.2 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain AAA_7 PF12775.7 EHU01774.1 - 0.00069 19.2 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 EHU01774.1 - 0.00087 19.0 0.0 0.17 11.6 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain TIP49 PF06068.13 EHU01774.1 - 0.0034 16.6 0.2 0.015 14.5 0.0 1.9 2 1 0 2 2 2 1 TIP49 P-loop domain Sigma54_activ_2 PF14532.6 EHU01774.1 - 0.0038 17.3 0.0 0.0089 16.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_18 PF13238.6 EHU01774.1 - 0.005 17.4 0.1 0.016 15.7 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.6 EHU01774.1 - 0.0052 16.5 0.1 0.0083 15.9 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EHU01774.1 - 0.0054 16.8 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EHU01774.1 - 0.0062 15.6 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_21 PF13304.6 EHU01774.1 - 0.007 16.2 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 EHU01774.1 - 0.0071 16.3 0.0 0.16 11.9 0.0 2.6 2 0 0 2 2 2 1 NACHT domain ATPase PF06745.13 EHU01774.1 - 0.0081 15.5 0.2 1.6 8.0 0.0 2.5 2 0 0 2 2 2 1 KaiC ABC_tran PF00005.27 EHU01774.1 - 0.0081 16.7 0.0 0.025 15.1 0.0 1.9 2 0 0 2 2 1 1 ABC transporter IstB_IS21 PF01695.17 EHU01774.1 - 0.0082 15.9 0.1 0.017 14.9 0.1 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 EHU01774.1 - 0.023 14.8 0.0 0.046 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EHU01774.1 - 0.048 13.7 0.0 0.097 12.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 EHU01774.1 - 0.049 13.4 0.1 0.13 12.1 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_8 PF12780.7 EHU01774.1 - 0.1 11.9 0.0 0.28 10.5 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 ResIII PF04851.15 EHU01774.1 - 0.1 12.6 0.1 0.35 10.9 0.1 2.0 2 1 0 2 2 1 0 Type III restriction enzyme, res subunit DEAD PF00270.29 EHU01774.1 - 0.11 12.3 0.9 0.63 9.8 0.1 2.4 2 1 0 3 3 3 0 DEAD/DEAH box helicase RNA_helicase PF00910.22 EHU01774.1 - 0.11 12.9 0.0 0.36 11.3 0.0 2.0 1 1 0 1 1 1 0 RNA helicase DUF1296 PF06972.11 EHU01774.1 - 0.12 12.6 0.0 0.41 10.8 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) PhoH PF02562.16 EHU01774.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 EHU01774.1 - 0.13 12.6 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_PrkA PF08298.11 EHU01774.1 - 0.13 11.2 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain AAA_19 PF13245.6 EHU01774.1 - 0.18 12.1 1.2 4.1 7.7 0.3 2.8 2 1 0 2 2 1 0 AAA domain AAA_23 PF13476.6 EHU01774.1 - 0.2 12.1 2.0 0.35 11.3 2.0 1.7 1 1 0 1 1 1 0 AAA domain CLP_protease PF00574.23 EHU01775.1 - 2.9e-90 301.0 0.0 3.4e-90 300.8 0.0 1.0 1 0 0 1 1 1 1 Clp protease Trigger_N PF05697.13 EHU01776.1 - 5e-43 146.8 2.2 5e-43 146.8 2.2 2.8 3 1 0 3 3 3 1 Bacterial trigger factor protein (TF) Trigger_C PF05698.14 EHU01776.1 - 2.1e-40 138.4 8.6 2.1e-40 138.4 8.6 2.7 3 0 0 3 3 3 1 Bacterial trigger factor protein (TF) C-terminus FKBP_C PF00254.28 EHU01776.1 - 7.4e-14 51.8 0.2 1.9e-13 50.5 0.2 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase BolA PF01722.18 EHU01777.1 - 1.7e-27 95.5 0.5 2e-27 95.2 0.5 1.1 1 0 0 1 1 1 1 BolA-like protein Lipoprotein_16 PF03923.13 EHU01778.1 - 5.1e-52 175.7 3.5 6.1e-52 175.5 3.5 1.1 1 0 0 1 1 1 1 Uncharacterized lipoprotein LPAM_1 PF08139.12 EHU01778.1 - 0.0032 17.9 2.6 0.0061 17.0 2.6 1.5 1 0 0 1 1 1 1 Prokaryotic membrane lipoprotein lipid attachment site AcylCoA_DH_N PF12418.8 EHU01778.1 - 0.014 15.4 0.2 0.029 14.4 0.2 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase N terminal MFS_1 PF07690.16 EHU01779.1 - 2.3e-32 112.3 33.1 2.3e-32 112.3 33.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Acatn PF13000.7 EHU01779.1 - 3.1e-13 49.1 4.8 1.8e-10 39.9 4.8 2.3 1 1 0 1 1 1 1 Acetyl-coenzyme A transporter 1 COX_ARM PF06481.14 EHU01780.1 - 6.8e-17 61.1 0.1 2.7e-16 59.2 0.3 1.9 2 0 0 2 2 2 1 COX Aromatic Rich Motif COX2 PF00116.20 EHU01780.1 - 3.3e-07 30.2 0.0 7.7e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain COX2_TM PF02790.15 EHU01780.1 - 0.004 17.3 1.7 0.0087 16.2 1.7 1.5 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, transmembrane domain DUF4079 PF13301.6 EHU01780.1 - 0.03 14.5 0.1 0.068 13.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) DUF996 PF06195.13 EHU01780.1 - 0.073 13.4 2.3 0.14 12.4 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF996) Cupredoxin_1 PF13473.6 EHU01780.1 - 0.13 12.4 0.0 0.35 11.0 0.0 1.7 1 1 0 1 1 1 0 Cupredoxin-like domain Sulf_transp PF04143.14 EHU01780.1 - 0.13 11.8 2.5 0.18 11.3 2.5 1.2 1 0 0 1 1 1 0 Sulphur transport Yip1 PF04893.17 EHU01780.1 - 1.5 8.5 7.2 6.4 6.5 7.0 1.9 1 1 1 2 2 2 0 Yip1 domain COX1 PF00115.20 EHU01781.1 - 3e-136 454.7 72.0 3e-136 454.7 72.0 2.3 3 0 0 3 3 3 1 Cytochrome C and Quinol oxidase polypeptide I COX3 PF00510.18 EHU01782.1 - 2e-16 60.6 15.4 2.8e-16 60.2 15.4 1.3 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III COX4_pro PF03626.14 EHU01783.1 - 6.8e-19 68.1 11.8 8.5e-19 67.8 11.8 1.1 1 0 0 1 1 1 1 Prokaryotic Cytochrome C oxidase subunit IV ABC2_membrane_5 PF13346.6 EHU01783.1 - 0.00028 20.5 10.6 0.00033 20.3 10.6 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein Polysacc_synt_C PF14667.6 EHU01783.1 - 0.0091 16.1 8.6 0.011 15.8 8.6 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis C-terminal domain ESSS PF10183.9 EHU01783.1 - 0.061 13.5 1.4 0.067 13.4 0.3 1.7 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) PhoLip_ATPase_C PF16212.5 EHU01783.1 - 0.13 12.0 8.3 0.14 11.9 8.3 1.0 1 0 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal DUF1218 PF06749.12 EHU01783.1 - 0.24 11.9 7.2 2.2 8.9 3.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) MtrF PF09472.10 EHU01783.1 - 0.31 10.5 0.1 0.31 10.5 0.1 2.4 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DUF3810 PF12725.7 EHU01783.1 - 0.34 10.2 7.3 0.4 10.0 7.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) Herpes_LMP1 PF05297.11 EHU01783.1 - 0.46 9.6 6.3 0.63 9.2 6.3 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF5518 PF17647.1 EHU01783.1 - 0.49 10.6 14.9 0.22 11.7 5.8 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5518) DUF3112 PF11309.8 EHU01783.1 - 0.82 9.1 6.6 0.96 8.9 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) UbiA PF01040.18 EHU01784.1 - 2e-58 197.6 23.8 2.4e-58 197.4 23.8 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family MFS_1 PF07690.16 EHU01785.1 - 1.2e-46 159.3 61.7 2.7e-39 135.1 39.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EHU01785.1 - 7.3e-09 35.0 33.8 4.9e-08 32.3 15.1 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 EHU01785.1 - 1.2e-07 30.9 27.9 1.3e-05 24.2 18.5 2.2 1 1 1 2 2 2 2 MFS_1 like family PUCC PF03209.15 EHU01785.1 - 0.016 14.2 36.1 0.65 8.9 25.7 2.9 1 1 1 2 2 2 0 PUCC protein MtrF PF09472.10 EHU01785.1 - 0.029 13.7 4.0 0.046 13.1 0.4 3.1 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DUF5391 PF17369.2 EHU01785.1 - 0.095 12.7 14.1 0.43 10.6 2.3 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF5391) DUF443 PF04276.12 EHU01785.1 - 0.41 10.4 5.4 0.39 10.5 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF443) DUF520 PF04461.13 EHU01786.1 - 6e-66 221.5 4.0 6.7e-66 221.4 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF520) Pyr_redox PF00070.27 EHU01786.1 - 0.1 13.1 2.4 2.3 8.8 0.3 2.2 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA_C PF08546.11 EHU01787.1 - 6.5e-34 116.8 0.3 1e-33 116.2 0.3 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EHU01787.1 - 1e-20 73.9 0.3 2.7e-20 72.6 0.3 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Rossmann-like PF10727.9 EHU01787.1 - 0.0045 16.8 0.6 3.3 7.6 0.2 2.6 1 1 1 2 2 2 2 Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 EHU01787.1 - 0.13 11.8 0.1 0.25 10.9 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.21 EHU01787.1 - 0.23 10.8 1.2 0.39 10.0 0.5 1.7 2 0 0 2 2 2 0 ThiF family TEX13 PF15186.6 EHU01787.1 - 1.4 8.6 4.5 2.5 7.8 0.5 2.1 1 1 0 2 2 2 0 Testis-expressed sequence 13 protein family DJ-1_PfpI PF01965.24 EHU01788.1 - 8.8e-46 155.7 0.0 1e-45 155.5 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 EHU01788.1 - 0.14 11.7 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain ThiI PF02568.14 EHU01789.1 - 9.2e-77 257.1 0.0 1.6e-76 256.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) THUMP PF02926.17 EHU01789.1 - 1.6e-23 83.4 0.8 1.6e-23 83.4 0.8 1.9 2 0 0 2 2 2 1 THUMP domain QueC PF06508.13 EHU01789.1 - 0.00057 19.4 0.1 0.14 11.7 0.0 2.7 2 1 0 2 2 2 2 Queuosine biosynthesis protein QueC Rhodanese PF00581.20 EHU01789.1 - 0.0077 16.7 0.2 0.15 12.6 0.1 2.8 2 1 0 2 2 2 1 Rhodanese-like domain Diphthami_syn_2 PF01902.17 EHU01789.1 - 0.015 14.8 2.4 0.05 13.1 0.0 2.7 2 1 0 3 3 3 0 Diphthamide synthase tRNA_Me_trans PF03054.16 EHU01789.1 - 0.021 13.6 0.1 0.094 11.5 0.0 2.1 2 0 0 2 2 2 0 tRNA methyl transferase B12-binding PF02310.19 EHU01789.1 - 0.078 13.0 0.6 0.97 9.5 0.0 2.3 2 0 0 2 2 2 0 B12 binding domain Exonuc_VII_S PF02609.16 EHU01790.1 - 9.1e-21 73.7 0.9 1.1e-20 73.4 0.9 1.1 1 0 0 1 1 1 1 Exonuclease VII small subunit Vps53_N PF04100.12 EHU01790.1 - 0.08 11.9 0.2 0.095 11.6 0.2 1.0 1 0 0 1 1 1 0 Vps53-like, N-terminal Activator_LAG-3 PF11498.8 EHU01790.1 - 0.095 11.7 1.4 0.11 11.5 1.4 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 sCache_2 PF17200.4 EHU01790.1 - 0.1 12.4 0.4 3.1 7.7 0.0 2.0 1 1 1 2 2 2 0 Single Cache domain 2 polyprenyl_synt PF00348.17 EHU01791.1 - 2.5e-55 187.3 0.2 3.1e-55 187.0 0.2 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DXP_synthase_N PF13292.6 EHU01792.1 - 3e-115 384.1 0.0 8.6e-115 382.6 0.0 1.7 2 1 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 EHU01792.1 - 9.5e-37 126.4 0.0 1.6e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EHU01792.1 - 5.8e-27 94.0 0.0 1.1e-26 93.2 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.20 EHU01792.1 - 4.8e-05 22.5 0.1 8.2e-05 21.7 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 EHU01792.1 - 0.0003 20.6 1.7 0.00055 19.8 0.1 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.21 EHU01792.1 - 0.00035 19.7 0.0 0.0054 15.7 0.1 2.5 3 0 0 3 3 3 1 Transketolase, thiamine diphosphate binding domain HTH_Tnp_1 PF01527.20 EHU01793.1 - 2.7e-10 40.4 0.0 5.4e-10 39.4 0.0 1.5 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.6 EHU01793.1 - 0.0054 16.5 0.0 0.0072 16.1 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 EHU01793.1 - 0.027 14.6 0.0 0.044 13.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain TnpB_IS66 PF05717.13 EHU01794.1 - 8.6e-12 44.9 0.0 9.4e-12 44.7 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHU01795.1 - 2.6e-98 329.0 3.0 1.9e-97 326.1 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU01795.1 - 5.5e-18 64.9 0.1 2.2e-17 63.0 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU01795.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU01795.1 - 6.8e-11 42.8 8.3 1.5e-10 41.7 8.3 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHU01795.1 - 0.017 14.9 6.4 0.027 14.3 6.4 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Phage_HK97_TLTM PF06120.11 EHU01795.1 - 0.022 14.0 1.7 0.042 13.0 1.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHU01795.1 - 0.022 15.1 4.3 0.091 13.1 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain FUSC PF04632.12 EHU01795.1 - 0.034 12.7 6.7 0.054 12.0 6.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 EHU01795.1 - 0.039 13.5 2.2 0.047 13.3 0.7 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Tho2 PF11262.8 EHU01795.1 - 0.056 12.6 0.5 0.094 11.9 0.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Troponin PF00992.20 EHU01795.1 - 0.062 13.6 3.0 0.11 12.8 3.0 1.3 1 0 0 1 1 1 0 Troponin LXG PF04740.12 EHU01795.1 - 0.11 12.2 2.6 0.33 10.6 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily UME PF08064.13 EHU01795.1 - 0.15 12.0 0.5 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain ERM PF00769.19 EHU01795.1 - 0.16 11.8 10.8 0.26 11.1 10.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HalX PF08663.10 EHU01795.1 - 0.23 11.8 3.1 0.59 10.5 3.1 1.7 1 0 0 1 1 1 0 HalX domain DHR10 PF18595.1 EHU01795.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF1192 PF06698.11 EHU01795.1 - 0.53 10.4 5.3 3.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Zn-ribbon_8 PF09723.10 EHU01795.1 - 0.55 10.4 2.4 0.92 9.7 0.2 2.3 2 0 0 2 2 2 0 Zinc ribbon domain TMPIT PF07851.13 EHU01795.1 - 1.1 8.4 3.1 1.7 7.8 3.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein OmpH PF03938.14 EHU01795.1 - 3.3 8.1 7.9 6.7 7.0 7.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HAUS-augmin3 PF14932.6 EHU01795.1 - 3.6 7.1 8.3 7.8 6.0 8.3 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 SlyX PF04102.12 EHU01795.1 - 7.1 7.3 8.7 7.7 7.2 1.0 3.0 1 1 1 2 2 2 0 SlyX PgpA PF04608.13 EHU01796.1 - 3.1e-54 182.9 7.0 3.9e-54 182.6 7.0 1.0 1 0 0 1 1 1 1 Phosphatidylglycerophosphatase A AIRS PF00586.24 EHU01797.1 - 2.8e-21 75.9 0.0 5.8e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain AIRS_C PF02769.22 EHU01797.1 - 3e-10 40.5 0.0 4.2e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain NusB PF01029.18 EHU01798.1 - 8.4e-35 119.9 0.1 1e-34 119.6 0.1 1.0 1 0 0 1 1 1 1 NusB family DMRL_synthase PF00885.19 EHU01799.1 - 6.1e-58 194.7 1.4 6.9e-58 194.5 1.4 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase RibD_C PF01872.17 EHU01800.1 - 7.3e-57 192.4 0.5 7.3e-57 192.4 0.5 1.5 2 0 0 2 2 2 1 RibD C-terminal domain dCMP_cyt_deam_1 PF00383.23 EHU01800.1 - 1.2e-22 79.7 0.1 1.9e-22 79.1 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EHU01800.1 - 1.4e-12 47.5 0.0 2.2e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase Inv-AAD PF18785.1 EHU01800.1 - 0.00048 20.0 0.0 0.00089 19.1 0.0 1.5 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase APOBEC_N PF08210.11 EHU01800.1 - 0.11 12.4 0.1 0.52 10.2 0.1 1.9 1 1 0 1 1 1 0 APOBEC-like N-terminal domain ATP-cone PF03477.16 EHU01801.1 - 5.3e-15 55.8 0.1 7.9e-15 55.2 0.1 1.3 1 0 0 1 1 1 1 ATP cone domain MalM PF07148.12 EHU01802.1 - 0.2 11.4 0.0 0.24 11.2 0.0 1.1 1 0 0 1 1 1 0 Maltose operon periplasmic protein precursor (MalM) DUF3251 PF11622.8 EHU01803.1 - 1.5e-50 171.1 3.8 1.8e-50 170.8 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3251) LPP PF04728.13 EHU01803.1 - 0.016 15.6 4.5 0.083 13.3 3.8 2.1 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DASH_Dad4 PF08650.10 EHU01803.1 - 0.033 14.2 0.1 0.061 13.3 0.1 1.4 1 0 0 1 1 1 0 DASH complex subunit Dad4 T2SSM PF04612.12 EHU01803.1 - 0.067 13.2 6.5 0.11 12.6 6.5 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M CLZ PF16526.5 EHU01803.1 - 0.089 13.2 0.6 19 5.7 0.2 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels bZIP_1 PF00170.21 EHU01803.1 - 0.13 12.4 0.2 0.22 11.6 0.2 1.3 1 0 0 1 1 1 0 bZIP transcription factor NPV_P10 PF05531.12 EHU01803.1 - 0.17 12.3 3.2 0.54 10.8 2.0 2.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4763 PF15960.5 EHU01803.1 - 1.2 8.4 5.0 1.7 7.9 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) YlqD PF11068.8 EHU01803.1 - 1.3 9.4 7.5 2.6 8.4 7.4 1.5 1 1 0 1 1 1 0 YlqD protein SecD_SecF PF02355.16 EHU01804.1 - 3.9e-66 222.1 15.0 6.5e-66 221.3 15.0 1.3 1 0 0 1 1 1 1 Protein export membrane protein Sec_GG PF07549.14 EHU01804.1 - 6.2e-11 41.4 0.1 1.4e-10 40.3 0.1 1.6 1 0 0 1 1 1 1 SecD/SecF GG Motif PIG-F PF06699.11 EHU01804.1 - 0.76 9.9 5.2 1.4 9.0 5.1 1.5 1 1 0 1 1 1 0 GPI biosynthesis protein family Pig-F PRA1 PF03208.19 EHU01804.1 - 3.7 7.2 9.4 0.76 9.4 0.5 2.5 1 1 1 2 2 2 0 PRA1 family protein SecD-TM1 PF13721.6 EHU01805.1 - 3e-41 140.0 9.0 1.4e-39 134.7 0.4 3.3 4 0 0 4 4 4 2 SecD export protein N-terminal TM region SecD_SecF PF02355.16 EHU01805.1 - 5e-17 61.9 10.1 9.5e-17 61.0 10.1 1.4 1 0 0 1 1 1 1 Protein export membrane protein MMPL PF03176.15 EHU01805.1 - 3.1e-09 36.2 11.8 3.1e-09 36.2 11.8 1.9 2 0 0 2 2 2 1 MMPL family Sec_GG PF07549.14 EHU01805.1 - 1.2e-07 30.9 0.0 2.7e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 SecD/SecF GG Motif Sterol-sensing PF12349.8 EHU01805.1 - 0.2 11.5 2.8 0.61 9.9 2.3 1.9 2 0 0 2 2 2 0 Sterol-sensing domain of SREBP cleavage-activation YajC PF02699.15 EHU01806.1 - 2.5e-26 91.4 0.5 2.9e-26 91.1 0.5 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Orf78 PF06024.12 EHU01806.1 - 0.0034 17.6 0.1 0.0058 16.9 0.1 1.3 1 0 0 1 1 1 1 Orf78 (ac78) MreC PF04085.14 EHU01806.1 - 0.014 15.3 0.1 0.018 14.9 0.1 1.2 1 0 0 1 1 1 0 rod shape-determining protein MreC DUF5385 PF17359.2 EHU01806.1 - 0.091 12.3 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5385) DUF1240 PF06836.12 EHU01806.1 - 0.11 13.1 0.0 0.15 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1240) PIRT PF15099.6 EHU01806.1 - 0.16 11.6 0.1 0.23 11.1 0.1 1.2 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family TGT PF01702.18 EHU01807.1 - 8e-154 512.0 0.0 9.8e-154 511.7 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase UPF0547 PF10571.9 EHU01809.1 - 0.0023 18.0 1.6 0.11 12.6 0.1 2.2 2 0 0 2 2 2 1 Uncharacterised protein family UPF0547 zinc_ribbon_2 PF13240.6 EHU01809.1 - 0.0023 17.6 1.4 0.16 11.7 0.0 2.3 2 0 0 2 2 2 1 zinc-ribbon domain DUF2225 PF09986.9 EHU01809.1 - 0.0072 16.1 0.7 0.11 12.2 0.0 2.0 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) zf-TFIIB PF13453.6 EHU01809.1 - 0.011 15.1 0.3 0.019 14.3 0.3 1.4 1 1 0 1 1 1 0 Transcription factor zinc-finger C1_1 PF00130.22 EHU01809.1 - 0.018 14.9 0.2 0.023 14.6 0.2 1.1 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_Tnp_IS1595 PF12760.7 EHU01809.1 - 0.024 14.6 0.1 0.033 14.2 0.1 1.3 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.6 EHU01809.1 - 0.026 13.9 2.8 2.3 7.8 0.6 2.2 2 0 0 2 2 2 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 EHU01809.1 - 0.028 14.4 1.0 0.2 11.7 0.0 2.1 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Prok-RING_1 PF14446.6 EHU01809.1 - 0.046 13.6 0.8 0.078 12.9 0.8 1.3 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 OrfB_Zn_ribbon PF07282.11 EHU01809.1 - 0.05 13.5 0.1 0.074 13.0 0.1 1.3 1 1 0 1 1 1 0 Putative transposase DNA-binding domain DUF2387 PF09526.10 EHU01809.1 - 0.08 13.1 0.8 0.091 12.9 0.8 1.1 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) RNA_POL_M_15KD PF02150.16 EHU01809.1 - 0.13 12.1 3.4 0.84 9.6 3.4 2.0 1 1 0 1 1 1 0 RNA polymerases M/15 Kd subunit zf-H2C2_2 PF13465.6 EHU01809.1 - 0.15 12.6 0.8 1.4 9.5 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger double domain Zn-C2H2_12 PF18112.1 EHU01809.1 - 0.49 10.9 0.2 0.49 10.9 0.2 2.1 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Exo_endo_phos PF03372.23 EHU01812.1 - 1.4e-06 28.0 0.3 9.4e-06 25.3 0.3 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 EHU01812.1 - 0.011 15.5 0.0 0.025 14.4 0.0 1.6 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase LysM PF01476.20 EHU01813.1 - 2.2e-27 94.9 0.2 7.7e-13 48.3 0.1 3.7 4 0 0 4 4 4 2 LysM domain SLT PF01464.20 EHU01813.1 - 2.3e-27 95.0 0.0 3.7e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 Transglycosylase SLT domain OapA PF04225.12 EHU01813.1 - 0.0016 18.5 0.2 0.087 12.9 0.0 3.2 3 0 0 3 3 3 1 Opacity-associated protein A LysM-like domain DUF3071 PF11268.8 EHU01813.1 - 0.048 13.7 0.0 0.83 9.7 0.0 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3071) RWP-RK PF02042.15 EHU01813.1 - 0.069 13.1 0.3 16 5.6 0.1 2.7 2 0 0 2 2 2 0 RWP-RK domain MLTD_N PF06474.12 EHU01813.1 - 0.075 13.2 1.1 0.13 12.5 0.5 1.8 2 0 0 2 2 2 0 MltD lipid attachment motif HAGH_C PF16123.5 EHU01814.1 - 2.4e-22 79.2 0.0 3.6e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 EHU01814.1 - 2.5e-21 76.6 0.5 9.7e-20 71.4 0.5 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EHU01814.1 - 7.9e-08 32.0 0.1 1.4e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EHU01814.1 - 0.021 14.7 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 EHU01814.1 - 0.044 13.2 0.0 0.079 12.4 0.0 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain Methyltransf_11 PF08241.12 EHU01815.1 - 2.6e-09 37.6 0.0 3.8e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EHU01815.1 - 0.0073 17.0 0.0 0.012 16.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EHU01815.1 - 0.019 14.8 0.0 0.025 14.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_29 PF03141.16 EHU01815.1 - 0.058 11.9 0.0 0.074 11.6 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.12 EHU01815.1 - 0.091 13.5 0.0 0.14 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 EHU01815.1 - 0.19 11.0 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family RNase_H PF00075.24 EHU01816.1 - 3.6e-55 186.1 0.0 4.1e-55 185.9 0.0 1.0 1 0 0 1 1 1 1 RNase H Fe-ADH PF00465.19 EHU01816.1 - 0.16 10.7 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase RNase_T PF00929.24 EHU01817.1 - 4.1e-39 134.8 0.0 5e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 EHU01817.1 - 1.1e-06 28.7 0.0 3.4e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like DNA_pol_A_exo1 PF01612.20 EHU01817.1 - 7.5e-05 22.5 0.0 0.0049 16.6 0.0 2.5 2 1 0 2 2 2 1 3'-5' exonuclease vATP-synt_AC39 PF01992.16 EHU01817.1 - 0.011 15.3 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 ATP synthase (C/AC39) subunit Transp_cyt_pur PF02133.15 EHU01818.1 - 8.6e-81 271.9 37.2 1e-80 271.7 37.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2976 PF11190.8 EHU01818.1 - 0.00011 21.9 1.8 0.052 13.3 0.0 4.2 3 1 1 4 4 4 2 Protein of unknown function (DUF2976) PRD1_DD PF11087.8 EHU01818.1 - 0.042 13.5 4.2 0.36 10.6 0.4 3.5 3 0 0 3 3 3 0 PRD1 phage membrane DNA delivery FCD PF07729.12 EHU01819.1 - 1.5e-15 57.7 2.6 2.9e-15 56.8 2.6 1.5 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 EHU01819.1 - 1.6e-15 56.5 0.5 3.4e-15 55.4 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_11 PF08279.12 EHU01819.1 - 0.01 15.7 0.2 0.041 13.8 0.0 2.0 2 0 0 2 2 2 0 HTH domain TrmB PF01978.19 EHU01819.1 - 0.033 14.1 0.0 0.31 10.9 0.0 2.4 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB HTH_DeoR PF08220.12 EHU01819.1 - 0.051 13.3 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain TFIIE_alpha PF02002.17 EHU01819.1 - 0.07 13.0 0.0 0.36 10.7 0.0 2.0 2 0 0 2 2 2 0 TFIIE alpha subunit Asp_Glu_race PF01177.22 EHU01820.1 - 1.1e-10 41.7 1.8 1.6e-10 41.2 1.8 1.2 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Amdase PF17645.1 EHU01820.1 - 7e-06 25.8 2.0 2.2e-05 24.2 0.7 2.0 2 0 0 2 2 2 1 Arylmalonate decarboxylase PEP-utilizers PF00391.23 EHU01820.1 - 0.037 13.7 0.1 0.037 13.7 0.1 2.2 3 0 0 3 3 3 0 PEP-utilising enzyme, mobile domain AIRC PF00731.20 EHU01820.1 - 0.07 12.7 0.9 0.36 10.4 0.1 2.2 1 1 1 2 2 2 0 AIR carboxylase Polysacc_deac_1 PF01522.21 EHU01821.1 - 3.2e-10 40.0 0.0 6.3e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Aldolase_II PF00596.21 EHU01822.1 - 5.7e-37 127.4 0.4 8.7e-37 126.9 0.4 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain SBP_bac_3 PF00497.20 EHU01823.1 - 2.2e-39 135.2 0.0 2.6e-39 135.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 EHU01823.1 - 0.0028 17.3 0.0 0.0043 16.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein Lig_chan-Glu_bd PF10613.9 EHU01823.1 - 0.029 14.6 0.1 0.076 13.2 0.1 1.7 1 1 0 1 1 1 0 Ligated ion channel L-glutamate- and glycine-binding site PhyH PF05721.13 EHU01824.1 - 6e-27 95.3 0.8 7.3e-27 95.0 0.8 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) ABC_tran PF00005.27 EHU01825.1 - 7e-34 117.3 0.0 1e-33 116.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter BPD_transp_1 PF00528.22 EHU01825.1 - 2.5e-22 79.5 13.4 4.6e-22 78.6 13.4 1.4 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component AAA_21 PF13304.6 EHU01825.1 - 8.4e-13 48.8 0.0 3e-06 27.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EHU01825.1 - 3.1e-07 30.1 0.3 9.8e-06 25.2 0.3 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EHU01825.1 - 0.00068 19.6 0.1 0.0016 18.4 0.1 1.6 1 1 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EHU01825.1 - 0.0015 18.9 0.1 0.0039 17.6 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EHU01825.1 - 0.002 17.9 0.0 0.0047 16.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EHU01825.1 - 0.0057 16.9 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 EHU01825.1 - 0.0066 15.3 0.2 0.84 8.3 0.1 2.9 2 1 0 2 2 2 1 Predicted ATPase of the ABC class AAA_13 PF13166.6 EHU01825.1 - 0.011 14.4 0.0 2.7 6.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EHU01825.1 - 0.016 15.3 0.1 0.037 14.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain DUF4212 PF13937.6 EHU01825.1 - 0.027 14.8 4.4 0.027 14.8 4.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4212) ATP_bind_1 PF03029.17 EHU01825.1 - 0.029 14.2 0.5 0.86 9.3 0.0 2.6 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA PF00004.29 EHU01825.1 - 0.041 14.3 0.0 1 9.8 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EHU01825.1 - 0.05 14.1 0.0 0.086 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EHU01825.1 - 0.051 13.3 0.1 0.24 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EHU01825.1 - 0.096 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain DLIC PF05783.11 EHU01825.1 - 0.15 10.9 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) PduV-EutP PF10662.9 EHU01825.1 - 0.18 11.6 0.0 0.43 10.3 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 EHU01825.1 - 0.21 11.8 0.0 0.47 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain LysR_substrate PF03466.20 EHU01827.1 - 3.4e-32 111.5 0.0 4.5e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EHU01827.1 - 5.4e-19 67.9 0.1 9.9e-19 67.1 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LNP1 PF15419.6 EHU01827.1 - 0.01 16.1 0.0 0.016 15.5 0.0 1.2 1 0 0 1 1 1 0 Leukemia NUP98 fusion partner 1 Pyr_redox_3 PF13738.6 EHU01828.1 - 1.8e-28 99.7 0.0 3e-27 95.7 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EHU01828.1 - 3.1e-11 42.4 0.0 1.2e-10 40.5 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EHU01828.1 - 3.2e-11 43.0 0.0 5.5e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EHU01828.1 - 4.2e-11 42.6 0.0 5e-10 39.1 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 EHU01828.1 - 1.5e-07 31.0 1.0 0.00073 18.9 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.6 EHU01828.1 - 9.2e-06 25.7 1.5 0.065 13.2 0.3 3.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 EHU01828.1 - 0.00019 20.2 0.2 1.8 7.1 0.1 3.1 3 0 0 3 3 3 2 HI0933-like protein Lycopene_cycl PF05834.12 EHU01828.1 - 0.00023 20.3 1.3 0.43 9.6 0.0 2.6 3 0 0 3 3 3 2 Lycopene cyclase protein GIDA PF01134.22 EHU01828.1 - 0.00036 19.7 0.0 1.2 8.2 0.0 3.3 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EHU01828.1 - 0.0017 18.5 0.1 1.7 8.9 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EHU01828.1 - 0.0025 17.4 5.5 4.5 6.7 0.2 3.4 2 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 EHU01828.1 - 0.0027 18.2 0.0 0.12 12.9 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EHU01828.1 - 0.0038 16.5 0.1 1.5 8.0 0.0 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_2 PF00890.24 EHU01828.1 - 0.019 14.1 2.9 2.7 7.0 0.3 3.1 3 0 0 3 3 3 0 FAD binding domain TrkA_N PF02254.18 EHU01828.1 - 0.038 14.2 0.1 3 8.1 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain Shikimate_DH PF01488.20 EHU01828.1 - 0.065 13.3 0.0 7.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 EHU01828.1 - 0.12 12.1 0.0 0.42 10.3 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 EHU01828.1 - 0.15 11.4 0.0 17 4.7 0.0 2.5 3 0 0 3 3 3 0 ThiF family Malic_M PF03949.15 EHU01828.1 - 0.21 10.9 0.0 4 6.6 0.0 2.1 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain Ribonuc_L-PSP PF01042.21 EHU01829.1 - 4.3e-21 75.2 0.0 5.2e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF1028 PF06267.12 EHU01830.1 - 1.4e-62 210.9 0.3 1.6e-62 210.7 0.3 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF1028) Peptidase_M20 PF01546.28 EHU01831.1 - 1.5e-33 116.2 0.0 2e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EHU01831.1 - 8.6e-24 83.6 0.0 1.4e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EHU01831.1 - 0.00071 19.3 0.0 0.0017 18.1 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.14 EHU01831.1 - 0.021 13.8 0.0 0.04 12.9 0.0 1.4 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase 2OG-FeII_Oxy_3 PF13640.6 EHU01832.1 - 6.5e-05 23.8 0.0 0.00011 23.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TauD PF02668.16 EHU01832.1 - 0.00016 21.6 1.5 0.54 10.0 0.6 2.8 2 1 0 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy PF03171.20 EHU01832.1 - 0.0012 19.3 0.0 0.0022 18.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 EHU01832.1 - 0.0036 17.6 0.0 0.7 10.1 0.0 2.2 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) LysR_substrate PF03466.20 EHU01833.1 - 9.7e-27 93.7 3.8 1.3e-26 93.2 3.8 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EHU01833.1 - 2.3e-19 69.1 0.8 4.2e-19 68.2 0.8 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 EHU01833.1 - 0.06 13.2 0.4 0.14 12.0 0.1 1.7 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain DUF3225 PF11533.8 EHU01834.1 - 9.1e-59 196.7 0.1 1e-58 196.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3225) DUF4440 PF14534.6 EHU01834.1 - 6.5e-08 32.9 0.4 7.9e-08 32.7 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 EHU01834.1 - 0.00015 22.0 0.0 0.00019 21.7 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 EHU01834.1 - 0.0017 18.5 0.5 0.0032 17.6 0.5 1.4 1 1 0 1 1 1 1 SnoaL-like domain Amidase PF01425.21 EHU01835.1 - 2e-100 336.9 0.2 5.6e-100 335.4 0.2 1.6 1 1 0 1 1 1 1 Amidase DUF4089 PF13318.6 EHU01836.1 - 2e-17 63.4 1.8 2.2e-17 63.2 1.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4089) G_glu_transpept PF01019.21 EHU01837.1 - 8.7e-133 443.8 0.2 9.9e-133 443.6 0.2 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase SIS PF01380.22 EHU01838.1 - 8.4e-14 51.5 0.0 1.2e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 SIS domain HTH_6 PF01418.17 EHU01838.1 - 2.1e-12 46.9 0.0 4.8e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family LacI PF00356.21 EHU01838.1 - 0.00025 20.8 0.0 0.00054 19.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family HTH_Crp_2 PF13545.6 EHU01838.1 - 0.00039 20.3 0.1 0.0023 17.9 0.0 2.5 2 1 1 3 3 3 1 Crp-like helix-turn-helix domain HTH_IclR PF09339.10 EHU01838.1 - 0.0052 16.5 0.1 0.027 14.3 0.0 2.3 2 0 0 2 2 2 1 IclR helix-turn-helix domain Crp PF00325.20 EHU01838.1 - 0.0092 15.6 0.4 0.028 14.1 0.1 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, crp family MarR_2 PF12802.7 EHU01838.1 - 0.01 15.7 0.3 0.043 13.7 0.0 2.2 2 0 0 2 2 2 0 MarR family MarR PF01047.22 EHU01838.1 - 0.014 15.3 0.1 0.065 13.2 0.0 2.2 2 0 0 2 2 2 0 MarR family HHH_5 PF14520.6 EHU01838.1 - 0.026 15.1 0.0 0.074 13.7 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain HTH_3 PF01381.22 EHU01838.1 - 0.03 14.4 0.0 0.093 12.8 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix Phage_min_cap2 PF06152.11 EHU01838.1 - 0.033 13.1 0.0 0.048 12.6 0.0 1.2 1 0 0 1 1 1 0 Phage minor capsid protein 2 HTH_24 PF13412.6 EHU01838.1 - 0.047 13.3 0.1 0.15 11.6 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_26 PF13443.6 EHU01838.1 - 0.067 13.6 0.8 0.25 11.8 0.0 2.4 3 0 0 3 3 2 0 Cro/C1-type HTH DNA-binding domain HTH_23 PF13384.6 EHU01838.1 - 0.072 12.9 0.1 0.6 10.0 0.0 2.5 2 0 0 2 2 2 0 Homeodomain-like domain HTH_31 PF13560.6 EHU01838.1 - 0.089 13.1 0.2 0.71 10.3 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_38 PF13936.6 EHU01838.1 - 0.13 12.0 0.2 2.8 7.8 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain Phage_CI_repr PF07022.13 EHU01838.1 - 0.14 12.3 0.0 0.43 10.7 0.0 1.8 1 1 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain SBP_bac_3 PF00497.20 EHU01839.1 - 6.3e-51 173.0 0.0 8.3e-51 172.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 EHU01839.1 - 5.3e-05 23.4 0.0 0.0032 17.6 0.0 2.3 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site NMT1 PF09084.11 EHU01839.1 - 0.00048 20.1 0.0 0.00076 19.5 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like BPD_transp_1 PF00528.22 EHU01840.1 - 4.7e-20 72.1 10.7 6.5e-20 71.6 10.7 1.1 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 EHU01841.1 - 8.2e-15 55.0 8.6 8.2e-15 55.0 8.6 1.5 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 EHU01842.1 - 4.2e-35 121.2 0.0 5.7e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EHU01842.1 - 2.8e-11 43.8 0.4 1.8e-05 24.7 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EHU01842.1 - 7.8e-10 38.6 0.0 1.1e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EHU01842.1 - 3.6e-05 23.4 0.1 7.4e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EHU01842.1 - 0.00066 20.0 0.7 0.0079 16.5 0.7 2.1 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 EHU01842.1 - 0.0017 17.2 0.9 2.5 6.8 0.1 2.9 2 1 0 2 2 2 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 EHU01842.1 - 0.0058 17.0 0.2 0.012 16.0 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 EHU01842.1 - 0.006 15.8 0.1 0.028 13.6 0.1 1.9 1 1 0 1 1 1 1 NB-ARC domain AAA_23 PF13476.6 EHU01842.1 - 0.011 16.3 0.1 0.017 15.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EHU01842.1 - 0.019 14.8 0.1 0.036 14.0 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 EHU01842.1 - 0.026 14.2 0.0 0.071 12.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EHU01842.1 - 0.049 13.2 0.1 0.76 9.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EHU01842.1 - 0.054 13.6 0.0 0.095 12.8 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.14 EHU01842.1 - 0.081 12.9 0.1 11 6.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 EHU01842.1 - 0.084 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Aminotran_5 PF00266.19 EHU01843.1 - 2.9e-27 95.6 0.0 2.4e-26 92.6 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V Peptidase_M20 PF01546.28 EHU01844.1 - 2.4e-25 89.5 0.1 3.1e-25 89.1 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 EHU01844.1 - 4.1e-06 26.6 0.0 7.2e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 M20_dimer PF07687.14 EHU01844.1 - 6.7e-05 22.8 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain OHCU_decarbox PF09349.10 EHU01845.1 - 1.1e-38 133.1 6.6 1.3e-38 133.0 6.6 1.0 1 0 0 1 1 1 1 OHCU decarboxylase DUF935 PF06074.12 EHU01845.1 - 0.011 14.5 5.4 0.014 14.2 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF935) SpoIIIAH PF12685.7 EHU01845.1 - 0.054 13.3 1.3 0.065 13.1 1.3 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Transthyretin PF00576.21 EHU01846.1 - 1.3e-31 109.6 0.0 1.4e-31 109.4 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family RVT_1 PF00078.27 EHU01847.1 - 8.7e-43 146.4 0.0 1.7e-42 145.4 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) GIIM PF08388.11 EHU01847.1 - 1.2e-17 63.7 4.0 3e-17 62.4 4.0 1.7 1 0 0 1 1 1 1 Group II intron, maturase-specific domain CN_hydrolase PF00795.22 EHU01848.1 - 1.7e-31 109.5 0.2 2e-31 109.3 0.2 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Aminotran_1_2 PF00155.21 EHU01849.1 - 9.8e-55 186.2 0.0 1.1e-54 186.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EHU01849.1 - 1e-05 24.3 0.0 1.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EHU01849.1 - 0.00087 18.3 0.0 0.0014 17.6 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EHU01849.1 - 0.022 14.1 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aldolase_II PF00596.21 EHU01850.1 - 6.4e-41 140.3 0.0 7.2e-41 140.2 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Hydrolase PF00702.26 EHU01851.1 - 9.3e-05 22.8 0.0 0.00036 20.9 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EHU01851.1 - 0.11 12.6 0.0 0.35 10.9 0.0 1.7 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase SecB PF02556.14 EHU01851.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit SecB ARD PF03079.14 EHU01852.1 - 2.1e-38 132.0 0.0 2.4e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 EHU01852.1 - 4.7e-06 26.2 0.0 7.8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EHU01852.1 - 0.047 13.6 0.1 0.072 13.0 0.1 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain IF-2B PF01008.17 EHU01853.1 - 6.2e-71 238.9 0.0 7.3e-71 238.6 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family ADIP PF11559.8 EHU01853.1 - 0.2 11.7 1.9 0.35 10.9 1.9 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding APH PF01636.23 EHU01854.1 - 1.1e-09 38.6 0.4 1.5e-09 38.1 0.4 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1974 PF09317.11 EHU01855.1 - 2.6e-115 384.9 0.8 3.5e-115 384.5 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1974) Acyl-CoA_dh_N PF02771.16 EHU01855.1 - 7.2e-17 62.1 0.1 2.5e-16 60.3 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 EHU01855.1 - 2.6e-14 53.7 0.7 8.3e-14 52.1 0.7 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EHU01855.1 - 4e-09 36.6 0.0 7.6e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain SIS_2 PF13580.6 EHU01856.1 - 6e-32 110.5 0.1 8.1e-32 110.1 0.1 1.2 1 0 0 1 1 1 1 SIS domain SIS PF01380.22 EHU01856.1 - 6.3e-09 35.8 0.0 1.3e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 SIS domain Antibiotic_NAT PF02522.14 EHU01856.1 - 0.11 12.3 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Aminoglycoside 3-N-acetyltransferase GATase_4 PF13230.6 EHU01857.1 - 1.4e-113 378.4 0.0 1.7e-113 378.1 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 EHU01857.1 - 8.1e-05 22.8 0.0 0.00014 22.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain YkuD PF03734.14 EHU01858.1 - 2.1e-06 28.2 0.2 4.5e-06 27.1 0.1 1.5 1 1 1 2 2 2 1 L,D-transpeptidase catalytic domain IMS PF00817.20 EHU01859.1 - 4.9e-49 166.2 0.0 7.6e-49 165.6 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EHU01859.1 - 4.9e-08 33.7 0.1 9.7e-08 32.7 0.1 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EHU01859.1 - 1.9e-05 24.7 0.0 5.2e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif Cdd1 PF11731.8 EHU01859.1 - 0.0035 17.5 0.0 0.0075 16.5 0.0 1.5 1 0 0 1 1 1 1 Pathogenicity locus DNA_pol_lambd_f PF10391.9 EHU01859.1 - 0.014 15.2 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda HHH_5 PF14520.6 EHU01859.1 - 0.035 14.7 0.0 0.073 13.7 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain Peripla_BP_4 PF13407.6 EHU01860.1 - 1.3e-28 100.3 5.2 1.7e-28 99.9 5.2 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_3 PF13377.6 EHU01860.1 - 4e-07 30.5 0.0 2.3e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 EHU01860.1 - 5.5e-07 29.3 0.1 8.1e-07 28.7 0.1 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family YcaO PF02624.16 EHU01860.1 - 0.00055 19.3 0.0 0.00092 18.6 0.0 1.3 1 0 0 1 1 1 1 YcaO cyclodehydratase, ATP-ad Mg2+-binding BPD_transp_2 PF02653.16 EHU01861.1 - 1.6e-39 135.7 42.1 2.5e-39 135.1 42.1 1.3 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component ABC_tran PF00005.27 EHU01862.1 - 5.7e-44 150.0 0.0 2.1e-22 80.1 0.0 2.4 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 EHU01862.1 - 7.9e-12 45.6 1.6 0.0015 18.4 0.0 3.6 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EHU01862.1 - 3.2e-07 30.3 0.2 0.00096 18.9 0.0 3.1 4 0 0 4 4 4 2 AAA domain SMC_N PF02463.19 EHU01862.1 - 3.9e-06 26.4 0.2 0.65 9.4 0.0 3.3 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EHU01862.1 - 6.6e-06 25.8 0.4 0.0002 21.0 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 EHU01862.1 - 8.9e-06 26.3 0.1 0.1 13.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EHU01862.1 - 4.1e-05 23.9 2.0 0.41 10.9 1.0 3.4 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EHU01862.1 - 6.2e-05 22.8 0.7 5.2 6.8 0.1 4.1 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_23 PF13476.6 EHU01862.1 - 8.1e-05 23.2 0.2 0.00081 20.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EHU01862.1 - 8.3e-05 22.5 0.1 0.1 12.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EHU01862.1 - 0.00015 22.2 1.0 0.24 11.7 0.2 2.5 2 0 0 2 2 2 2 AAA ATPase domain Viral_helicase1 PF01443.18 EHU01862.1 - 0.00062 19.6 0.0 0.024 14.4 0.0 3.0 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase AAA_27 PF13514.6 EHU01862.1 - 0.0013 18.3 0.1 0.0035 17.0 0.1 1.6 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EHU01862.1 - 0.0014 18.7 0.4 2.2 8.4 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.6 EHU01862.1 - 0.0038 16.8 0.1 0.06 12.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EHU01862.1 - 0.0059 16.7 0.0 2.7 8.1 0.0 3.0 4 0 0 4 4 3 1 AAA domain SbcCD_C PF13558.6 EHU01862.1 - 0.007 16.6 0.1 0.83 9.9 0.0 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 EHU01862.1 - 0.0089 16.2 0.2 3.4 7.8 0.1 2.9 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EHU01862.1 - 0.009 15.3 0.2 1.7 7.9 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.6 EHU01862.1 - 0.017 15.4 1.5 0.35 11.1 0.1 2.8 3 0 0 3 3 3 0 AAA domain MeaB PF03308.16 EHU01862.1 - 0.02 13.9 0.4 3 6.7 0.1 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 EHU01862.1 - 0.024 15.0 0.0 0.9 10.0 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 EHU01862.1 - 0.028 14.4 0.6 3.4 7.7 0.1 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MukB PF04310.12 EHU01862.1 - 0.03 14.1 0.2 0.057 13.2 0.2 1.4 1 0 0 1 1 1 0 MukB N-terminal NB-ARC PF00931.22 EHU01862.1 - 0.04 13.1 0.1 4.5 6.4 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.19 EHU01862.1 - 0.068 12.8 1.0 7.9 6.0 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain APS_kinase PF01583.20 EHU01862.1 - 0.13 12.2 1.0 2 8.3 0.1 2.5 2 1 0 2 2 2 0 Adenylylsulphate kinase PduV-EutP PF10662.9 EHU01862.1 - 0.13 12.0 0.1 16 5.3 0.0 2.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.15 EHU01862.1 - 0.14 12.0 0.0 1.8 8.4 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain SRP54 PF00448.22 EHU01862.1 - 0.29 10.7 0.6 5.1 6.7 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NACHT PF05729.12 EHU01862.1 - 0.36 10.7 3.0 4.2 7.3 0.0 2.9 3 0 0 3 3 3 0 NACHT domain ATP_bind_1 PF03029.17 EHU01862.1 - 0.54 10.0 1.8 7.3 6.3 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PALP PF00291.25 EHU01863.1 - 3.9e-80 269.4 0.0 4.4e-80 269.2 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FtsA PF14450.6 EHU01863.1 - 0.17 12.3 0.0 11 6.4 0.0 2.5 2 1 0 2 2 2 0 Cell division protein FtsA HTH_Tnp_1 PF01527.20 EHU01864.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU01864.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU01864.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU01864.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHU01865.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHU01866.1 - 1.1e-97 326.9 4.0 3.8e-97 325.1 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU01866.1 - 3.2e-16 59.2 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU01866.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU01866.1 - 1.2e-11 45.2 9.0 2.6e-11 44.1 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHU01866.1 - 0.017 14.9 6.4 0.027 14.3 6.4 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Phage_HK97_TLTM PF06120.11 EHU01866.1 - 0.022 14.0 1.7 0.042 13.0 1.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHU01866.1 - 0.022 15.1 4.3 0.091 13.1 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain FUSC PF04632.12 EHU01866.1 - 0.038 12.6 6.8 0.06 11.9 6.8 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 EHU01866.1 - 0.04 13.5 2.2 0.047 13.2 0.8 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Tho2 PF11262.8 EHU01866.1 - 0.057 12.6 0.5 0.094 11.9 0.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Troponin PF00992.20 EHU01866.1 - 0.062 13.6 3.0 0.11 12.8 3.0 1.3 1 0 0 1 1 1 0 Troponin LXG PF04740.12 EHU01866.1 - 0.11 12.3 2.5 0.32 10.7 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily UME PF08064.13 EHU01866.1 - 0.15 12.0 0.5 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain ERM PF00769.19 EHU01866.1 - 0.16 11.8 10.8 0.26 11.1 10.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HalX PF08663.10 EHU01866.1 - 0.23 11.8 3.1 0.59 10.5 3.1 1.7 1 0 0 1 1 1 0 HalX domain DHR10 PF18595.1 EHU01866.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Zn-ribbon_8 PF09723.10 EHU01866.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF1192 PF06698.11 EHU01866.1 - 0.53 10.4 5.3 3.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHU01866.1 - 1.1 8.4 3.1 1.7 7.8 3.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHU01866.1 - 2.8 7.4 7.9 6.1 6.3 7.9 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHU01866.1 - 3.3 8.1 7.9 6.7 7.0 7.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 EHU01866.1 - 7.2 7.3 8.7 7.7 7.2 1.0 3.0 1 1 1 2 2 2 0 SlyX Peptidase_M20 PF01546.28 EHU01867.1 - 5.3e-20 72.0 0.0 9.9e-20 71.1 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EHU01867.1 - 6.4e-07 29.3 0.1 1.7e-06 27.9 0.1 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain STAS_2 PF13466.6 EHU01867.1 - 0.013 15.8 0.1 0.035 14.5 0.1 1.7 1 0 0 1 1 1 0 STAS domain Pribosyltran PF00156.27 EHU01868.1 - 2.3e-17 62.9 0.0 2.9e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF1100 PF06500.11 EHU01869.1 - 6.3e-178 591.7 0.0 7e-178 591.6 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) AXE1 PF05448.12 EHU01869.1 - 0.1 11.2 0.0 0.48 9.1 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DLH PF01738.18 EHU01869.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family LYTB PF02401.18 EHU01869.1 - 0.17 11.1 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 LytB protein Crl PF07417.12 EHU01870.1 - 8.7e-51 171.0 0.0 9.8e-51 170.9 0.0 1.0 1 0 0 1 1 1 1 Sigma factor-binding transcriptional regulator Crl Porin_1 PF00267.21 EHU01871.1 - 6.3e-139 463.1 29.5 7.1e-139 463.0 29.5 1.0 1 0 0 1 1 1 1 Gram-negative porin OMP_b-brl PF13505.6 EHU01871.1 - 0.0059 16.8 43.3 0.025 14.7 17.5 3.2 1 1 1 2 2 2 1 Outer membrane protein beta-barrel domain AA_kinase PF00696.28 EHU01872.1 - 3.5e-42 144.7 1.3 5e-42 144.1 1.3 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 EHU01872.1 - 1.9e-20 72.6 0.1 5.2e-20 71.2 0.1 1.8 1 0 0 1 1 1 1 PUA domain Aldedh PF00171.22 EHU01873.1 - 1.5e-17 63.3 2.0 1.8e-12 46.6 0.4 2.2 2 0 0 2 2 2 2 Aldehyde dehydrogenase family FlgT_N PF16548.5 EHU01873.1 - 0.017 15.6 2.1 0.28 11.8 0.1 2.8 2 0 0 2 2 2 0 Flagellar assembly protein T, N-terminal domain CPSase_L_D3 PF02787.19 EHU01873.1 - 0.061 13.7 0.2 8.6 6.7 0.0 2.6 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Peptidase_S24 PF00717.23 EHU01874.1 - 2.2e-08 33.9 0.0 3.8e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like HTH_3 PF01381.22 EHU01874.1 - 0.024 14.7 0.0 0.056 13.5 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix Phage_lysozyme PF00959.19 EHU01876.1 - 0.19 12.2 0.0 0.27 11.7 0.0 1.2 1 0 0 1 1 1 0 Phage lysozyme UPF0114 PF03350.16 EHU01877.1 - 1.2 9.4 7.1 15 5.8 7.1 2.3 1 1 0 1 1 1 0 Uncharacterized protein family, UPF0114 DUF2514 PF10721.9 EHU01878.1 - 0.024 14.7 4.7 0.03 14.3 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Oberon_cc PF16312.5 EHU01878.1 - 0.033 14.1 5.0 0.04 13.9 5.0 1.1 1 0 0 1 1 1 0 Coiled-coil region of Oberon Pectate_lyase_3 PF12708.7 EHU01879.1 - 1.5e-10 41.3 1.0 6.3e-10 39.3 1.0 2.1 1 1 0 1 1 1 1 Pectate lyase superfamily protein End_N_terminal PF12218.8 EHU01879.1 - 0.022 14.4 0.0 0.057 13.1 0.0 1.7 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase Fe-ADH PF00465.19 EHU01880.1 - 6.8e-69 232.4 5.7 7.7e-69 232.2 5.7 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EHU01880.1 - 3.9e-33 115.2 0.6 4.9e-33 114.9 0.6 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 EHU01880.1 - 1.8e-05 24.1 2.0 9.1e-05 21.7 2.0 2.1 1 1 0 1 1 1 1 3-dehydroquinate synthase FAD_binding_4 PF01565.23 EHU01880.1 - 0.0097 15.6 0.9 0.59 9.9 0.1 3.1 3 1 0 3 3 3 1 FAD binding domain PFK PF00365.20 EHU01880.1 - 0.035 13.4 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 Phosphofructokinase Dak1 PF02733.17 EHU01881.1 - 6.1e-125 416.2 0.0 7e-125 416.0 0.0 1.0 1 0 0 1 1 1 1 Dak1 domain SH3_13 PF18335.1 EHU01881.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain Dak2 PF02734.17 EHU01882.1 - 9.4e-54 181.9 2.3 1.1e-53 181.7 2.3 1.0 1 0 0 1 1 1 1 DAK2 domain EIIA-man PF03610.16 EHU01883.1 - 3.6e-25 88.5 2.4 7.6e-25 87.4 2.4 1.6 1 0 0 1 1 1 1 PTS system fructose IIA component PEP-utilisers_N PF05524.13 EHU01883.1 - 1.4e-20 73.6 0.5 1.4e-20 73.6 0.5 2.0 2 0 0 2 2 2 1 PEP-utilising enzyme, N-terminal PTS-HPr PF00381.19 EHU01883.1 - 2.6e-15 56.4 1.4 4.1e-15 55.8 0.0 2.2 2 0 0 2 2 2 1 PTS HPr component phosphorylation site PEP-utilizers PF00391.23 EHU01883.1 - 2.4e-13 49.6 0.2 6.5e-13 48.2 0.2 1.7 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain LSDAT_prok PF18171.1 EHU01883.1 - 0.013 14.7 1.0 0.031 13.5 1.0 1.6 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote ShlB PF03865.13 EHU01884.1 - 9.4e-95 317.6 9.1 1.2e-94 317.3 9.1 1.1 1 0 0 1 1 1 1 Haemolysin secretion/activation protein ShlB/FhaC/HecB POTRA_2 PF08479.11 EHU01884.1 - 6.9e-25 86.7 0.1 7.7e-24 83.3 0.1 2.3 2 0 0 2 2 2 1 POTRA domain, ShlB-type POTRA_3 PF17287.2 EHU01884.1 - 1.8e-19 68.9 0.4 3.7e-19 67.9 0.4 1.6 1 0 0 1 1 1 1 POTRA domain POTRA PF07244.15 EHU01884.1 - 0.035 14.7 0.0 0.37 11.4 0.0 2.3 2 0 0 2 2 2 0 Surface antigen variable number repeat DDE_3 PF13358.6 EHU01885.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHU01885.1 - 7.7e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHU01885.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHU01885.1 - 3.6e-06 26.5 0.3 3.6e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHU01885.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHU01885.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHU01885.1 - 0.087 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHU01885.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 DDE_3 PF13358.6 EHU01886.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHU01886.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHU01886.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHU01886.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHU01886.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHU01886.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHU01886.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHU01886.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 DDE_3 PF13358.6 EHU01887.1 - 1.1e-22 80.3 0.0 1.9e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 EHU01887.1 - 1.1e-10 41.0 1.0 3.6e-09 36.2 0.1 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 EHU01887.1 - 4.1e-09 36.9 1.1 2.8e-08 34.3 0.3 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 EHU01887.1 - 4e-07 30.0 1.2 1.1e-06 28.6 0.3 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHU01887.1 - 1.4e-05 25.1 0.3 0.0002 21.4 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_33 PF13592.6 EHU01887.1 - 6e-05 22.6 5.4 8.3e-05 22.1 0.5 3.0 3 0 0 3 3 3 1 Winged helix-turn helix LZ_Tnp_IS481 PF13011.6 EHU01887.1 - 0.029 14.9 0.2 0.061 13.8 0.2 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 HTH_38 PF13936.6 EHU01887.1 - 0.052 13.3 0.6 0.16 11.8 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 EHU01888.1 - 0.02 15.2 0.0 0.022 15.1 0.0 1.2 1 0 0 1 1 1 0 Transposase LysR_substrate PF03466.20 EHU01889.1 - 8.6e-28 97.1 5.0 1.4e-27 96.5 5.0 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EHU01889.1 - 1.2e-15 57.2 0.2 2.2e-15 56.3 0.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 EHU01889.1 - 2.6e-05 23.9 0.1 5.3e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_AsnC-type PF13404.6 EHU01889.1 - 0.006 16.4 0.9 0.014 15.2 0.9 1.6 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain MarR_2 PF12802.7 EHU01889.1 - 0.01 15.7 0.4 0.029 14.2 0.4 1.8 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.6 EHU01889.1 - 0.012 15.1 0.3 0.027 14.0 0.3 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 EHU01889.1 - 0.074 13.2 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 EHU01889.1 - 0.097 12.1 0.0 0.27 10.7 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Fe_dep_repress PF01325.19 EHU01889.1 - 0.13 12.5 0.1 0.29 11.4 0.1 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_5 PF01022.20 EHU01889.1 - 0.18 11.7 0.6 0.55 10.1 0.3 2.0 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Flavodoxin_2 PF02525.17 EHU01890.1 - 2.3e-54 184.2 0.0 2.8e-54 183.8 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 EHU01890.1 - 1.3e-13 50.9 0.0 3.2e-13 49.7 0.0 1.5 1 1 0 1 1 1 1 NADPH-dependent FMN reductase CSD PF00313.22 EHU01891.1 - 2.6e-33 113.7 0.7 2.8e-33 113.6 0.7 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 EHU01891.1 - 0.00027 20.6 0.4 0.0004 20.0 0.4 1.4 1 1 0 1 1 1 1 Ribonuclease B OB domain CusF_Ec PF11604.8 EHU01891.1 - 0.047 13.7 0.1 0.069 13.1 0.1 1.3 1 0 0 1 1 1 0 Copper binding periplasmic protein CusF CheW PF01584.19 EHU01893.1 - 6.2e-29 100.4 0.1 9.5e-29 99.8 0.1 1.2 1 0 0 1 1 1 1 CheW-like domain Response_reg PF00072.24 EHU01893.1 - 4.8e-16 58.9 0.1 1.1e-15 57.8 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain BOF PF04076.13 EHU01894.1 - 5.4e-20 71.4 0.7 6.7e-20 71.1 0.7 1.1 1 0 0 1 1 1 1 Bacterial OB fold (BOF) protein YDG PF18657.1 EHU01894.1 - 0.0023 18.1 3.8 0.011 15.9 0.6 2.3 1 1 1 2 2 2 1 YDG domain tRNA_anti-codon PF01336.25 EHU01894.1 - 0.0047 16.9 0.2 0.01 15.8 0.1 1.6 1 1 1 2 2 2 1 OB-fold nucleic acid binding domain YflT PF11181.8 EHU01894.1 - 0.015 15.8 0.1 0.02 15.4 0.1 1.2 1 0 0 1 1 1 0 Heat induced stress protein YflT DEAD PF00270.29 EHU01895.1 - 1.9e-46 158.0 0.0 3.1e-46 157.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EHU01895.1 - 3.6e-31 107.8 0.0 2.1e-28 98.9 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DbpA PF03880.15 EHU01895.1 - 1.9e-22 79.0 0.1 5.2e-22 77.6 0.1 1.7 1 0 0 1 1 1 1 DbpA RNA binding domain ResIII PF04851.15 EHU01895.1 - 9.2e-08 32.3 0.0 2e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EHU01895.1 - 0.00019 20.8 0.0 0.00051 19.5 0.0 1.7 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.6 EHU01895.1 - 0.014 15.8 0.0 0.4 11.0 0.0 2.5 1 1 1 2 2 2 0 AAA domain Helicase_RecD PF05127.14 EHU01895.1 - 0.097 12.5 0.0 0.33 10.8 0.0 1.9 2 0 0 2 2 2 0 Helicase LysR_substrate PF03466.20 EHU01896.1 - 2.2e-20 72.9 3.8 3.9e-20 72.1 3.8 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EHU01896.1 - 2.6e-20 72.1 0.8 5e-20 71.2 0.8 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_24 PF13412.6 EHU01896.1 - 0.00011 21.7 0.2 0.00028 20.4 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 EHU01896.1 - 0.00078 19.2 0.1 0.0021 17.9 0.1 1.8 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain MarR_2 PF12802.7 EHU01896.1 - 0.00092 19.1 0.8 0.0026 17.6 0.1 2.1 2 0 0 2 2 2 1 MarR family HTH_20 PF12840.7 EHU01896.1 - 0.011 15.8 0.1 0.066 13.3 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_30 PF13556.6 EHU01896.1 - 0.011 15.5 0.0 0.033 14.0 0.0 1.7 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_23 PF13384.6 EHU01896.1 - 0.021 14.6 0.0 0.34 10.8 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain MarR PF01047.22 EHU01896.1 - 0.037 13.9 0.0 0.09 12.7 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_5 PF01022.20 EHU01896.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family MFS_1 PF07690.16 EHU01897.1 - 5e-22 78.3 54.9 5e-22 78.3 54.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Lactate_perm PF02652.14 EHU01898.1 - 1.9e-210 700.1 41.3 2.2e-210 699.9 41.3 1.0 1 0 0 1 1 1 1 L-lactate permease FCD PF07729.12 EHU01899.1 - 7.8e-25 87.7 11.1 1.6e-24 86.7 11.1 1.5 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 EHU01899.1 - 7.6e-18 63.9 0.2 1.7e-17 62.8 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Rrf2 PF02082.20 EHU01899.1 - 0.0011 19.3 0.0 0.0034 17.7 0.0 1.8 2 0 0 2 2 2 1 Transcriptional regulator HTH_24 PF13412.6 EHU01899.1 - 0.0061 16.1 0.2 0.012 15.2 0.2 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 EHU01899.1 - 0.0073 16.3 0.1 0.014 15.4 0.1 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_11 PF08279.12 EHU01899.1 - 0.011 15.7 0.1 0.026 14.5 0.1 1.6 1 0 0 1 1 1 0 HTH domain MarR_2 PF12802.7 EHU01899.1 - 0.051 13.5 0.2 0.13 12.1 0.2 1.7 1 0 0 1 1 1 0 MarR family HTH_29 PF13551.6 EHU01899.1 - 0.052 13.6 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HTH_CodY PF08222.11 EHU01899.1 - 0.17 11.5 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 CodY helix-turn-helix domain TrmB PF01978.19 EHU01899.1 - 0.17 11.8 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.7 EHU01899.1 - 0.2 11.8 3.9 1.2 9.3 0.1 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain DUF2538 PF10804.8 EHU01899.1 - 0.2 11.4 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2538) FMN_dh PF01070.18 EHU01900.1 - 1.2e-123 412.6 0.0 1.4e-123 412.4 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EHU01900.1 - 6.4e-06 25.4 2.0 1.8e-05 24.0 0.7 2.1 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EHU01900.1 - 0.00032 20.2 1.7 0.00047 19.6 1.7 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IGPS PF00218.21 EHU01900.1 - 0.0024 17.1 0.0 0.0074 15.5 0.0 1.8 1 1 0 1 1 1 1 Indole-3-glycerol phosphate synthase Glu_synthase PF01645.17 EHU01900.1 - 0.0041 16.3 0.4 0.0059 15.8 0.4 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 EHU01900.1 - 0.0078 15.5 0.4 1.2 8.4 0.5 2.3 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 EHU01900.1 - 0.066 12.7 0.1 0.56 9.6 0.1 2.1 1 1 1 2 2 2 0 Histidine biosynthesis protein OsmC PF02566.19 EHU01901.1 - 1.6e-20 73.5 0.0 1.9e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 OsmC-like protein DUF4006 PF13179.6 EHU01902.1 - 0.69 9.9 3.8 0.83 9.6 3.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF4006) PTS_IIB PF02302.17 EHU01905.1 - 3.2e-26 91.8 0.6 3.6e-26 91.7 0.6 1.0 1 0 0 1 1 1 1 PTS system, Lactose/Cellobiose specific IIB subunit PTS_EIIC PF02378.18 EHU01906.1 - 1.3e-58 198.6 35.0 1.7e-58 198.2 35.0 1.1 1 0 0 1 1 1 1 Phosphotransferase system, EIIC End3 PF12761.7 EHU01906.1 - 0.016 15.4 0.0 0.025 14.7 0.0 1.1 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 HTH_35 PF13693.6 EHU01907.1 - 2.5e-24 85.1 0.0 2.7e-24 85.0 0.0 1.0 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding DUF3234 PF11572.8 EHU01907.1 - 0.17 12.1 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3234) Mu-transpos_C PF09299.11 EHU01908.1 - 1.1e-14 54.1 0.0 3.3e-14 52.6 0.0 1.9 1 0 0 1 1 1 1 Mu transposase, C-terminal rve PF00665.26 EHU01908.1 - 6.1e-12 45.8 0.0 1.4e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_Tnp_Mu_1 PF02316.16 EHU01908.1 - 1.8e-06 28.2 0.1 1.3e-05 25.4 0.0 2.4 2 0 0 2 2 2 1 Mu DNA-binding domain rve_3 PF13683.6 EHU01908.1 - 0.024 14.4 0.0 2.1 8.2 0.0 2.9 2 0 0 2 2 2 0 Integrase core domain AAA_22 PF13401.6 EHU01909.1 - 1.2e-17 64.4 0.2 3.4e-17 63.0 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EHU01909.1 - 6.7e-06 26.0 0.1 1.2e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain HTH_3 PF01381.22 EHU01909.1 - 2.5e-05 24.2 0.2 6.3e-05 23.0 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix TniB PF05621.11 EHU01909.1 - 0.00032 20.2 0.0 0.002 17.6 0.0 2.1 1 1 0 1 1 1 1 Bacterial TniB protein HTH_31 PF13560.6 EHU01909.1 - 0.0013 19.1 0.1 0.0053 17.1 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain AAA_16 PF13191.6 EHU01909.1 - 0.0016 18.8 0.1 0.0051 17.2 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EHU01909.1 - 0.0086 16.1 0.3 0.022 14.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 EHU01909.1 - 0.013 15.3 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase HTH_24 PF13412.6 EHU01909.1 - 0.015 14.8 0.0 0.072 12.7 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding LacI PF00356.21 EHU01909.1 - 0.016 15.0 0.2 0.04 13.7 0.2 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family AAA PF00004.29 EHU01909.1 - 0.045 14.2 0.0 0.21 12.0 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Adeno_IVa2 PF02456.15 EHU01909.1 - 0.065 12.0 0.0 0.087 11.6 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein HTH_40 PF14493.6 EHU01909.1 - 0.075 13.5 0.1 0.23 12.0 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain AAA_24 PF13479.6 EHU01909.1 - 0.095 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain GerE PF00196.19 EHU01909.1 - 0.11 12.1 0.1 0.33 10.5 0.1 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Mu-transpos_C PF09299.11 EHU01911.1 - 6.3e-05 22.9 0.8 0.00012 22.0 0.8 1.5 1 0 0 1 1 1 1 Mu transposase, C-terminal DUF3164 PF11363.8 EHU01915.1 - 2.8e-70 235.9 0.5 3.2e-70 235.7 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3164) HTH_Tnp_1 PF01527.20 EHU01916.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU01916.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU01916.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU01916.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHU01917.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHU01918.1 - 3e-98 328.8 3.4 1.9e-97 326.1 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU01918.1 - 3.4e-16 59.2 0.1 1.3e-15 57.3 0.1 2.1 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU01918.1 - 1.4e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU01918.1 - 8.7e-11 42.4 9.0 1.9e-10 41.4 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Phage_HK97_TLTM PF06120.11 EHU01918.1 - 0.029 13.6 0.7 0.056 12.6 0.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein UME PF08064.13 EHU01918.1 - 0.038 13.9 0.4 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain Exonuc_VII_L PF02601.15 EHU01918.1 - 0.041 13.4 2.5 0.044 13.4 0.9 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit FUSC PF04632.12 EHU01918.1 - 0.063 11.8 7.7 0.1 11.1 7.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Csm1_N PF18504.1 EHU01918.1 - 0.13 12.7 3.4 0.86 10.0 0.2 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Tho2 PF11262.8 EHU01918.1 - 0.17 11.0 0.3 0.28 10.4 0.3 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DHR10 PF18595.1 EHU01918.1 - 0.18 11.9 10.2 0.31 11.1 10.2 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain ERM PF00769.19 EHU01918.1 - 0.28 11.0 10.4 0.45 10.3 10.4 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family LXG PF04740.12 EHU01918.1 - 0.28 10.9 2.4 0.86 9.3 0.3 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily HHH_8 PF14716.6 EHU01918.1 - 0.34 11.3 4.0 0.56 10.6 1.9 2.4 2 1 0 2 2 2 0 Helix-hairpin-helix domain Zn-ribbon_8 PF09723.10 EHU01918.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain TSNAXIP1_N PF15739.5 EHU01918.1 - 0.46 10.9 3.2 0.99 9.8 3.2 1.5 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus FAM184 PF15665.5 EHU01918.1 - 0.49 10.1 7.3 0.78 9.5 7.3 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B TMPIT PF07851.13 EHU01918.1 - 0.77 8.9 2.7 1.2 8.4 2.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein CREPT PF16566.5 EHU01918.1 - 2.3 8.4 8.3 1.1 9.5 5.2 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour HAUS-augmin3 PF14932.6 EHU01918.1 - 2.5 7.6 7.4 5.8 6.4 7.4 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 SlyX PF04102.12 EHU01918.1 - 8.1 7.2 8.7 17 6.1 2.1 3.0 1 1 1 2 2 2 0 SlyX RSN1_7TM PF02714.15 EHU01922.1 - 0.0014 18.1 0.3 0.0015 18.0 0.3 1.0 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate Colicin_V PF02674.16 EHU01922.1 - 0.017 15.1 0.5 0.019 14.9 0.5 1.1 1 0 0 1 1 1 0 Colicin V production protein DUF1018 PF06252.12 EHU01923.1 - 6.4e-24 85.2 0.3 7.5e-24 85.0 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1018) Mor PF08765.11 EHU01924.1 - 1.4e-09 37.9 0.0 6.7e-08 32.5 0.0 2.1 1 1 1 2 2 2 2 Mor transcription activator family Phage_lysozyme PF00959.19 EHU01925.1 - 6.4e-19 68.4 0.0 8e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Phage lysozyme TrbC PF04956.13 EHU01926.1 - 0.018 15.2 2.6 0.022 15.0 2.6 1.1 1 0 0 1 1 1 0 TrbC/VIRB2 family DUF2644 PF10841.8 EHU01927.1 - 6.6e-05 23.0 0.1 0.00011 22.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2644) DUF1282 PF06930.12 EHU01927.1 - 0.025 14.4 0.0 0.025 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) SLATT_1 PF18181.1 EHU01927.1 - 0.048 13.6 0.2 0.058 13.3 0.2 1.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 UPF0016 PF01169.19 EHU01927.1 - 0.079 13.3 0.7 0.12 12.7 0.7 1.2 1 0 0 1 1 1 0 Uncharacterized protein family UPF0016 DUF962 PF06127.11 EHU01927.1 - 0.084 13.0 0.2 0.11 12.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF962) DUF3789 PF12664.7 EHU01927.1 - 0.44 10.3 3.9 2.8 7.7 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3789) EzrA PF06160.12 EHU01930.1 - 0.0093 14.2 0.5 0.011 14.0 0.5 1.0 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA MetOD2 PF18548.1 EHU01930.1 - 0.018 15.2 0.9 0.022 14.9 0.9 1.1 1 0 0 1 1 1 0 Metanogen output domain 2 ZapB PF06005.12 EHU01930.1 - 0.03 14.8 0.7 0.052 14.0 0.7 1.3 1 0 0 1 1 1 0 Cell division protein ZapB zf-CCCH_6 PF18585.1 EHU01930.1 - 0.12 12.3 0.2 0.2 11.5 0.2 1.4 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 LMBR1 PF04791.16 EHU01930.1 - 0.13 11.1 0.1 0.15 11.0 0.1 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1804 PF08822.11 EHU01932.1 - 2.1e-54 183.9 0.9 2.4e-54 183.7 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1804) Rsa3 PF14615.6 EHU01932.1 - 0.012 15.1 0.1 1.8 8.2 0.0 2.6 3 0 0 3 3 3 0 Ribosome-assembly protein 3 FIVAR PF07554.13 EHU01932.1 - 0.77 10.6 3.9 0.43 11.4 1.2 1.9 1 1 1 2 2 2 0 FIVAR domain FdhE PF04216.12 EHU01934.1 - 0.00091 19.2 1.1 0.0013 18.7 1.1 1.4 1 1 0 1 1 1 1 Protein involved in formate dehydrogenase formation Cys_rich_KTR PF14205.6 EHU01934.1 - 0.15 11.9 0.4 14 5.5 0.1 2.3 2 0 0 2 2 2 0 Cysteine-rich KTR zf-RRN7 PF11781.8 EHU01934.1 - 0.29 10.9 7.0 4.6 7.0 3.8 2.3 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zinc-ribbons_6 PF07191.12 EHU01934.1 - 0.7 9.9 4.4 11 6.1 4.4 2.1 1 1 1 2 2 2 0 zinc-ribbons Zn_ribbon_SprT PF17283.2 EHU01934.1 - 0.7 9.8 7.7 4.6 7.2 2.1 2.3 1 1 2 3 3 3 0 SprT-like zinc ribbon domain DUF935 PF06074.12 EHU01936.1 - 4.8e-172 573.3 0.0 5.4e-172 573.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF935) Phage_Mu_F PF04233.14 EHU01937.1 - 3.5e-30 105.0 0.0 5.7e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 Phage Mu protein F like protein Phage_tail_S PF05069.13 EHU01938.1 - 4.2e-15 55.9 0.2 7.9e-15 55.0 0.2 1.4 1 1 0 1 1 1 1 Phage virion morphogenesis family HK97-gp10_like PF04883.12 EHU01938.1 - 0.072 14.1 0.0 0.14 13.1 0.0 1.5 1 1 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component PhageMin_Tail PF10145.9 EHU01939.1 - 2.7e-13 50.3 8.3 2.7e-13 50.3 8.3 2.4 2 1 0 2 2 2 1 Phage-related minor tail protein End_N_terminal PF12218.8 EHU01939.1 - 0.0031 17.2 0.2 0.032 13.9 0.0 2.5 2 0 0 2 2 2 1 N terminal extension of bacteriophage endosialidase DUF3209 PF11483.8 EHU01939.1 - 0.029 14.8 0.0 0.061 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) DNA_circ_N PF07157.12 EHU01940.1 - 1.2e-25 89.7 0.0 2.6e-25 88.6 0.0 1.6 1 0 0 1 1 1 1 DNA circularisation protein N-terminus Baculo_PEP_C PF04513.12 EHU01940.1 - 2.6 8.1 12.1 0.12 12.4 1.3 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_Mu_Gp45 PF06890.12 EHU01942.1 - 1.7e-36 123.9 0.1 2.7e-36 123.3 0.1 1.3 1 0 0 1 1 1 1 Bacteriophage Mu Gp45 protein Phage_spike PF18715.1 EHU01942.1 - 1.1e-08 34.9 9.9 1.4e-07 31.5 9.9 2.5 1 1 0 1 1 1 1 Phage spike trimer PEP-utilizers PF00391.23 EHU01942.1 - 0.00057 19.6 2.2 0.33 10.7 0.1 3.3 3 0 0 3 3 3 2 PEP-utilising enzyme, mobile domain Plug PF07715.15 EHU01942.1 - 0.039 14.5 1.0 0.095 13.3 1.0 1.7 1 0 0 1 1 1 0 TonB-dependent Receptor Plug Domain CHRD PF07452.12 EHU01942.1 - 0.07 14.1 2.2 0.11 13.5 0.5 2.1 1 1 1 2 2 2 0 CHRD domain GP46 PF07409.12 EHU01943.1 - 1.8e-10 40.6 0.0 2.4e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Phage protein GP46 Baseplate_J PF04865.14 EHU01944.1 - 5e-58 196.3 9.4 6.4e-58 195.9 9.4 1.1 1 0 0 1 1 1 1 Baseplate J-like protein DUF2313 PF10076.9 EHU01945.1 - 1.1e-31 110.0 0.0 1.2e-31 109.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2313) Nif11 PF07862.11 EHU01945.1 - 0.0074 16.6 0.0 0.019 15.2 0.0 1.7 1 0 0 1 1 1 1 Nif11 domain 2_5_RNA_ligase2 PF13563.6 EHU01945.1 - 0.043 13.7 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily Collar PF07484.12 EHU01946.1 - 4.8e-10 39.3 0.2 9.4e-10 38.4 0.2 1.5 1 0 0 1 1 1 1 Phage Tail Collar Domain Rib PF08428.10 EHU01946.1 - 0.083 12.9 0.1 0.82 9.7 0.0 2.6 3 0 0 3 3 3 0 Rib/alpha-like repeat Caudo_TAP PF02413.17 EHU01947.1 - 8.1e-26 90.7 1.0 1.1e-25 90.2 1.0 1.2 1 0 0 1 1 1 1 Caudovirales tail fibre assembly protein, lambda gpK Phage_tail_APC PF16778.5 EHU01947.1 - 0.02 14.7 1.1 0.02 14.7 1.1 2.5 2 1 0 2 2 2 0 Phage tail assembly chaperone protein DUF445 PF04286.12 EHU01948.1 - 0.051 13.4 0.1 0.057 13.2 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF4841 PF16129.5 EHU01948.1 - 0.053 13.8 0.2 0.084 13.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4841) PqqD PF05402.12 EHU01948.1 - 0.053 13.8 0.4 0.94 9.8 0.2 2.2 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) DUF4795 PF16043.5 EHU01948.1 - 0.089 12.4 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) MethyltransfD12 PF02086.15 EHU01950.1 - 2.7e-19 69.8 0.0 2.9e-19 69.8 0.0 1.0 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase MethyltransfD12 PF02086.15 EHU01951.1 - 0.0059 16.3 0.0 0.009 15.7 0.0 1.4 1 1 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Baculo_RING PF05883.11 EHU01951.1 - 0.015 15.3 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain PTS_IIA PF02255.16 EHU01954.1 - 7.2e-32 109.3 5.3 8e-32 109.2 5.3 1.0 1 0 0 1 1 1 1 PTS system, Lactose/Cellobiose specific IIA subunit Glyco_hydro_1 PF00232.18 EHU01955.1 - 8.3e-146 486.0 0.1 1e-145 485.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Peripla_BP_3 PF13377.6 EHU01956.1 - 1.2e-30 107.1 0.9 2.7e-30 105.9 0.3 1.8 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 EHU01956.1 - 1.2e-26 93.8 0.3 1.5e-26 93.5 0.3 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 EHU01956.1 - 2.6e-20 71.9 0.5 4.9e-20 71.0 0.5 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 EHU01956.1 - 9.9e-16 58.1 0.0 1.8e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_6 PF13458.6 EHU01956.1 - 0.00056 19.7 0.3 0.017 14.8 0.0 2.2 1 1 1 2 2 2 1 Periplasmic binding protein HTH_31 PF13560.6 EHU01956.1 - 0.0016 18.7 0.4 0.0044 17.3 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 EHU01956.1 - 0.0019 18.2 0.0 0.0039 17.2 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_IclR PF09339.10 EHU01956.1 - 0.047 13.5 0.0 0.18 11.6 0.0 2.1 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 EHU01956.1 - 0.05 13.0 0.2 0.19 11.2 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 TetR_N PF00440.23 EHU01956.1 - 0.061 13.1 0.1 0.17 11.7 0.1 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family MarR_2 PF12802.7 EHU01956.1 - 0.1 12.5 0.0 0.32 10.9 0.0 1.8 1 0 0 1 1 1 0 MarR family HTH_38 PF13936.6 EHU01956.1 - 0.14 12.0 0.0 0.51 10.1 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain CPBP PF02517.16 EHU01957.1 - 3e-17 62.8 10.2 3e-17 62.8 10.2 2.4 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease Inhibitor_I78 PF11720.8 EHU01958.1 - 6.7e-12 45.3 0.0 8.8e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family YmgB PF10798.8 EHU01960.1 - 6.9e-11 41.8 0.0 8.7e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Biofilm development protein YmgB/AriR Secretin_N PF03958.17 EHU01960.1 - 0.045 14.2 0.1 0.065 13.6 0.1 1.4 1 1 0 1 1 1 0 Bacterial type II/III secretion system short domain DUF4777 PF16007.5 EHU01960.1 - 0.13 12.5 0.0 0.2 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) HTH_Tnp_1 PF01527.20 EHU01961.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU01961.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU01961.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU01961.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHU01962.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHU01963.1 - 1.1e-97 326.9 4.5 3.8e-97 325.1 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU01963.1 - 3.2e-16 59.3 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU01963.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU01963.1 - 8.7e-11 42.4 9.0 1.9e-10 41.4 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Phage_HK97_TLTM PF06120.11 EHU01963.1 - 0.011 15.0 0.8 0.021 14.0 0.8 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHU01963.1 - 0.02 15.2 4.2 0.084 13.2 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain UME PF08064.13 EHU01963.1 - 0.033 14.1 0.3 20 5.1 0.0 3.1 2 1 1 3 3 3 0 UME (NUC010) domain Exonuc_VII_L PF02601.15 EHU01963.1 - 0.039 13.5 2.7 0.04 13.5 1.0 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Troponin PF00992.20 EHU01963.1 - 0.044 14.1 2.8 0.078 13.3 2.8 1.3 1 0 0 1 1 1 0 Troponin FUSC PF04632.12 EHU01963.1 - 0.048 12.2 7.4 0.077 11.5 7.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tho2 PF11262.8 EHU01963.1 - 0.049 12.8 0.6 0.081 12.1 0.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FAM184 PF15665.5 EHU01963.1 - 0.052 13.3 8.0 0.082 12.7 8.0 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B HalX PF08663.10 EHU01963.1 - 0.13 12.6 2.4 0.34 11.3 2.4 1.7 1 0 0 1 1 1 0 HalX domain LXG PF04740.12 EHU01963.1 - 0.14 11.8 2.8 0.35 10.5 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHU01963.1 - 0.19 11.5 11.1 0.31 10.8 11.1 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DHR10 PF18595.1 EHU01963.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Zn-ribbon_8 PF09723.10 EHU01963.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF1192 PF06698.11 EHU01963.1 - 0.54 10.4 5.3 3.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHU01963.1 - 0.82 8.9 3.0 1.2 8.3 3.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHU01963.1 - 2 8.0 8.1 4.3 6.8 8.1 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHU01963.1 - 4.2 7.7 8.6 8.7 6.7 8.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CREPT PF16566.5 EHU01963.1 - 5.9 7.1 8.7 2.7 8.1 5.6 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour SlyX PF04102.12 EHU01963.1 - 9.3 7.0 9.0 18 6.1 2.3 3.0 1 1 1 2 2 2 0 SlyX BPD_transp_1 PF00528.22 EHU01964.1 - 7.2e-29 100.8 61.1 2.5e-18 66.4 20.5 4.2 2 2 2 4 4 4 3 Binding-protein-dependent transport system inner membrane component SBP_bac_6 PF13343.6 EHU01965.1 - 5.9e-23 81.5 1.1 8.5e-23 81.0 1.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 EHU01965.1 - 1.4e-21 77.4 2.0 1.9e-21 76.9 2.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 EHU01965.1 - 2e-16 60.8 5.3 4.3e-16 59.7 5.3 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 EHU01965.1 - 3.1e-16 60.0 3.6 4.3e-16 59.6 3.6 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein PBP_like_2 PF12849.7 EHU01965.1 - 0.00014 21.6 0.0 0.0067 16.1 0.0 2.3 2 0 0 2 2 2 1 PBP superfamily domain Glyco_tran_WecB PF03808.13 EHU01965.1 - 0.0033 17.4 0.0 0.0052 16.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase WecB/TagA/CpsF family LysR_substrate PF03466.20 EHU01965.1 - 0.034 13.5 0.0 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 LysR substrate binding domain DUF2880 PF11082.8 EHU01965.1 - 0.078 13.3 0.0 0.51 10.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2880) Acetyltransf_5 PF13444.6 EHU01966.1 - 1.7e-24 86.4 0.0 4.3e-24 85.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acyltransferase PF01553.21 EHU01966.1 - 3.4e-11 42.9 0.0 7e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Cupin_2 PF07883.11 EHU01967.1 - 2.3e-08 33.6 0.1 4.8e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EHU01967.1 - 1.5e-05 24.6 0.0 2.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.7 EHU01967.1 - 0.0067 16.2 0.0 0.0082 15.9 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 EHU01967.1 - 0.036 13.8 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) AraC_binding PF02311.19 EHU01967.1 - 0.062 13.2 0.1 0.094 12.6 0.1 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain SBP_bac_3 PF00497.20 EHU01968.1 - 2e-33 115.7 0.0 2.3e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 LysR_substrate PF03466.20 EHU01968.1 - 0.0013 18.1 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 LysR substrate binding domain NMT1 PF09084.11 EHU01968.1 - 0.081 12.9 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 NMT1/THI5 like ABC_tran PF00005.27 EHU01969.1 - 1.9e-35 122.3 0.0 2.7e-35 121.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EHU01969.1 - 7.3e-17 62.1 0.3 1.1e-08 35.3 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EHU01969.1 - 1.6e-08 34.3 0.0 0.001 18.6 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EHU01969.1 - 1.8e-05 24.3 0.1 4.1e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EHU01969.1 - 5.1e-05 23.7 0.1 0.00012 22.5 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 EHU01969.1 - 5.6e-05 23.0 0.0 0.0012 18.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 EHU01969.1 - 6.1e-05 23.6 0.0 0.00011 22.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_13 PF13166.6 EHU01969.1 - 6.2e-05 21.9 0.0 0.026 13.2 0.0 2.0 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 EHU01969.1 - 0.00011 21.1 0.1 0.26 10.0 0.0 2.9 2 1 0 2 2 2 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 EHU01969.1 - 0.00021 21.3 0.0 0.00035 20.5 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase ATPase_2 PF01637.18 EHU01969.1 - 0.00038 20.5 0.0 0.0011 18.9 0.0 1.7 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EHU01969.1 - 0.00071 19.9 0.2 0.0031 17.8 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EHU01969.1 - 0.0067 16.5 0.0 0.19 11.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain cobW PF02492.19 EHU01969.1 - 0.012 15.3 0.1 0.037 13.6 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.6 EHU01969.1 - 0.013 15.8 0.1 1.2 9.4 0.1 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 EHU01969.1 - 0.014 15.1 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 EHU01969.1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EHU01969.1 - 0.017 15.1 0.0 0.041 13.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 EHU01969.1 - 0.021 15.0 0.0 0.04 14.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EHU01969.1 - 0.027 15.0 0.1 0.14 12.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain CobU PF02283.16 EHU01969.1 - 0.035 13.7 0.1 1 8.9 0.0 2.5 2 1 1 3 3 3 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Adeno_IVa2 PF02456.15 EHU01969.1 - 0.042 12.7 0.1 0.079 11.7 0.0 1.4 2 0 0 2 2 2 0 Adenovirus IVa2 protein NB-ARC PF00931.22 EHU01969.1 - 0.066 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.6 EHU01969.1 - 0.067 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EHU01969.1 - 0.071 13.0 0.0 0.16 11.9 0.0 1.5 2 0 0 2 2 1 0 Rad17 P-loop domain FtsK_SpoIIIE PF01580.18 EHU01969.1 - 0.1 12.0 0.1 0.28 10.5 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_28 PF13521.6 EHU01969.1 - 0.14 12.4 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EHU01969.1 - 0.15 12.2 0.1 1.1 9.4 0.0 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase BPD_transp_1 PF00528.22 EHU01970.1 - 3.4e-18 66.0 18.4 3.4e-18 66.0 18.4 1.8 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Acetyltransf_1 PF00583.25 EHU01971.1 - 2e-11 44.2 0.3 2.6e-11 43.8 0.3 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EHU01971.1 - 1.1e-06 28.6 0.0 1.5e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EHU01971.1 - 5e-06 26.8 0.0 7.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EHU01971.1 - 0.00061 19.7 0.0 0.00087 19.2 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein GNAT_acetyltran PF12746.7 EHU01971.1 - 0.16 11.5 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase SBP_bac_3 PF00497.20 EHU01972.1 - 3.1e-37 128.2 0.1 4.6e-37 127.6 0.1 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Bac_luciferase PF00296.20 EHU01973.1 - 2.2e-68 231.0 1.4 3.4e-68 230.4 1.1 1.4 1 1 0 1 1 1 1 Luciferase-like monooxygenase Peptidase_M20 PF01546.28 EHU01974.1 - 1.7e-30 106.3 0.4 2.1e-30 106.0 0.4 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EHU01974.1 - 2.5e-13 49.9 0.0 2.5e-13 49.9 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Bac_luciferase PF00296.20 EHU01975.1 - 7.7e-29 101.1 3.8 1.1e-28 100.5 3.8 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase DDE_3 PF13358.6 EHU01976.1 - 1.2e-22 80.3 0.0 1.6e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHU01976.1 - 8.1e-09 36.0 0.3 2.3e-08 34.5 0.3 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHU01976.1 - 1.8e-08 34.0 0.7 8.5e-07 28.6 0.0 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHU01976.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 2.6 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHU01976.1 - 4.3e-06 26.6 0.4 1.9e-05 24.6 0.2 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHU01976.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHU01976.1 - 0.089 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHU01976.1 - 0.11 13.1 0.1 0.2 12.2 0.1 1.4 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 Peptidase_M20 PF01546.28 EHU01978.1 - 1.3e-29 103.4 0.1 1.6e-29 103.1 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EHU01978.1 - 3.8e-10 39.6 0.1 8.2e-10 38.6 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain YlaC PF10777.9 EHU01979.1 - 1.8e-58 196.7 0.0 2.1e-58 196.6 0.0 1.0 1 0 0 1 1 1 1 Inner membrane protein YlaC DUF2244 PF10003.9 EHU01979.1 - 0.25 11.0 1.9 0.43 10.2 1.9 1.4 1 1 0 1 1 1 0 Integral membrane protein (DUF2244) EAL PF00563.20 EHU01980.1 - 1.8e-71 240.4 0.0 3.4e-71 239.5 0.0 1.5 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 EHU01980.1 - 2.7e-46 157.2 0.0 4.4e-46 156.6 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain MHYT PF03707.16 EHU01980.1 - 1.4e-44 150.1 54.1 2.2e-17 63.0 6.1 4.9 5 0 0 5 5 5 4 Bacterial signalling protein N terminal repeat SCPU PF05229.15 EHU01981.1 - 4.7e-21 75.7 13.8 5.8e-21 75.3 13.8 1.1 1 0 0 1 1 1 1 Spore Coat Protein U domain SCPU PF05229.15 EHU01982.1 - 7.1e-29 101.0 10.6 8.9e-29 100.7 10.6 1.1 1 0 0 1 1 1 1 Spore Coat Protein U domain PapD_N PF00345.20 EHU01983.1 - 3.7e-20 72.1 0.2 5.2e-20 71.6 0.2 1.2 1 0 0 1 1 1 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain LTD PF00932.19 EHU01983.1 - 0.12 12.7 0.0 0.51 10.7 0.0 1.9 2 0 0 2 2 2 0 Lamin Tail Domain SCPU PF05229.15 EHU01984.1 - 6.9e-40 136.7 21.6 5.1e-27 95.0 9.3 2.1 2 0 0 2 2 2 2 Spore Coat Protein U domain Sugar_tr PF00083.24 EHU01985.1 - 2.3e-33 115.8 30.3 7.3e-25 87.7 5.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EHU01985.1 - 4.5e-28 98.2 51.5 1.3e-19 70.4 25.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF872 PF05915.12 EHU01985.1 - 0.12 12.6 0.1 0.12 12.6 0.1 2.7 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF872) ExbD PF02472.16 EHU01986.1 - 1.6e-29 102.7 1.0 1.9e-29 102.5 1.0 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR MotA_ExbB PF01618.16 EHU01987.1 - 4.5e-33 113.7 1.5 8.6e-33 112.8 1.5 1.5 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family Vpu PF00558.19 EHU01987.1 - 0.52 10.1 1.4 1.7 8.5 0.1 2.1 2 0 0 2 2 2 0 Vpu protein LapA_dom PF06305.11 EHU01987.1 - 6.3 6.7 7.8 0.37 10.6 1.3 2.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain MFS_1 PF07690.16 EHU01989.1 - 7e-53 179.8 64.5 4.9e-50 170.4 43.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EHU01989.1 - 5.6e-27 94.7 32.5 3.3e-24 85.6 7.9 2.1 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 EHU01989.1 - 3.3e-09 36.5 9.8 3.3e-09 36.5 9.8 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 EHU01989.1 - 0.0039 16.1 15.0 0.095 11.5 8.2 2.5 2 0 0 2 2 2 2 MFS_1 like family UPF0227 PF05728.12 EHU01989.1 - 0.15 12.0 0.8 2.7 7.9 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) DUF4381 PF14316.6 EHU01989.1 - 0.22 11.7 7.1 1.1 9.4 1.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Dioxygenase_C PF00775.21 EHU01990.1 - 1.3e-54 184.4 0.0 1.7e-54 184.0 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase PCDO_beta_N PF12391.8 EHU01990.1 - 1.6e-13 50.0 3.1 3.3e-13 49.0 3.1 1.6 1 0 0 1 1 1 1 Protocatechuate 3,4-dioxygenase beta subunit N terminal CarboxypepD_reg PF13620.6 EHU01990.1 - 1.8e-06 28.2 0.0 7e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4198 PF10670.9 EHU01990.1 - 0.093 13.1 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) Dioxygenase_C PF00775.21 EHU01991.1 - 2e-20 73.0 0.0 1.6e-19 70.1 0.0 1.9 1 1 0 1 1 1 1 Dioxygenase LysR_substrate PF03466.20 EHU01992.1 - 2.2e-31 108.9 6.4 3.3e-31 108.3 6.4 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EHU01992.1 - 3.8e-17 62.0 4.0 9e-17 60.8 4.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_20 PF12840.7 EHU01992.1 - 0.076 13.1 0.4 0.37 10.9 0.2 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_8 PF02954.19 EHU01992.1 - 0.42 10.5 0.1 0.42 10.5 0.1 2.6 4 0 0 4 4 4 0 Bacterial regulatory protein, Fis family CMD PF02627.20 EHU01993.1 - 2.9e-25 88.1 1.6 6.2e-25 87.1 0.1 2.4 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Thiolase_N PF00108.23 EHU01993.1 - 1.2e-06 28.1 0.0 2.9e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_4 PF08386.10 EHU01993.1 - 0.0043 17.2 0.1 0.0074 16.4 0.1 1.4 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.8 EHU01993.1 - 0.0079 15.5 0.1 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 CoA_trans PF01144.23 EHU01994.1 - 3.7e-33 114.7 0.0 4.6e-33 114.5 0.0 1.0 1 0 0 1 1 1 1 Coenzyme A transferase CoA_trans PF01144.23 EHU01995.1 - 1.4e-67 227.3 0.1 1.5e-67 227.1 0.1 1.0 1 0 0 1 1 1 1 Coenzyme A transferase IclR PF01614.18 EHU01996.1 - 1.9e-32 111.8 0.1 3e-32 111.2 0.1 1.3 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 EHU01996.1 - 7.9e-16 57.6 0.4 3.5e-15 55.5 0.1 2.4 2 0 0 2 2 2 1 IclR helix-turn-helix domain Rrf2 PF02082.20 EHU01996.1 - 4.9e-06 26.8 0.0 2.2e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 Transcriptional regulator TrmB PF01978.19 EHU01996.1 - 9.1e-05 22.3 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 EHU01996.1 - 0.00016 21.5 0.2 0.00054 19.8 0.1 2.0 2 0 0 2 2 2 1 MarR family HTH_5 PF01022.20 EHU01996.1 - 0.00042 20.1 0.0 0.0061 16.4 0.0 2.6 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family DUF4423 PF14394.6 EHU01996.1 - 0.0034 17.1 0.0 0.071 12.8 0.0 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4423) HTH_9 PF08221.11 EHU01996.1 - 0.0053 16.8 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_11 PF08279.12 EHU01996.1 - 0.007 16.3 0.0 0.1 12.6 0.0 2.4 2 0 0 2 2 2 1 HTH domain HTH_24 PF13412.6 EHU01996.1 - 0.012 15.2 0.0 0.041 13.4 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding RP-C PF03428.13 EHU01996.1 - 0.024 14.3 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 Replication protein C N-terminal domain HTH_20 PF12840.7 EHU01996.1 - 0.032 14.3 0.0 0.22 11.6 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain RPA_C PF08784.11 EHU01996.1 - 0.077 13.7 0.0 0.18 12.5 0.0 1.5 1 0 0 1 1 1 0 Replication protein A C terminal Cullin PF00888.22 EHU01996.1 - 0.26 9.9 0.0 0.41 9.2 0.0 1.2 1 0 0 1 1 1 0 Cullin family Cys_Met_Meta_PP PF01053.20 EHU01997.1 - 5.3e-117 390.6 0.0 6e-117 390.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EHU01997.1 - 0.00098 18.2 0.1 0.0014 17.6 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 EHU01997.1 - 0.15 10.6 0.0 0.22 10.0 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase SNARE_assoc PF09335.11 EHU01998.1 - 3.4e-19 69.5 5.9 3.4e-19 69.5 5.9 1.7 2 0 0 2 2 2 1 SNARE associated Golgi protein TMEM154 PF15102.6 EHU01998.1 - 0.026 14.4 0.5 0.039 13.9 0.5 1.2 1 0 0 1 1 1 0 TMEM154 protein family Tetraspanin PF00335.20 EHU01998.1 - 0.11 12.2 0.6 0.26 10.9 0.6 1.6 1 0 0 1 1 1 0 Tetraspanin family DUF4448 PF14610.6 EHU01998.1 - 0.12 12.1 0.6 0.24 11.2 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) PIRT PF15099.6 EHU01998.1 - 2.6 7.6 7.9 13 5.4 0.6 2.2 1 1 1 2 2 2 0 Phosphoinositide-interacting protein family Aldo_ket_red PF00248.21 EHU01999.1 - 2.6e-52 177.9 0.1 6.3e-50 170.0 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Peptidase_S49 PF01343.18 EHU01999.1 - 0.056 13.4 0.0 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 Peptidase family S49 DDE_Tnp_IS66 PF03050.14 EHU02000.1 - 2.8e-98 328.9 3.5 1.9e-97 326.1 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU02000.1 - 3.3e-16 59.2 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU02000.1 - 1.4e-14 54.2 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU02000.1 - 8.7e-11 42.4 9.0 1.9e-10 41.4 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Phage_HK97_TLTM PF06120.11 EHU02000.1 - 0.011 15.0 0.8 0.021 14.0 0.8 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHU02000.1 - 0.02 15.2 4.2 0.084 13.2 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain UME PF08064.13 EHU02000.1 - 0.033 14.1 0.3 20 5.1 0.0 3.1 2 1 1 3 3 3 0 UME (NUC010) domain Exonuc_VII_L PF02601.15 EHU02000.1 - 0.039 13.5 2.7 0.04 13.5 1.0 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Troponin PF00992.20 EHU02000.1 - 0.044 14.1 2.8 0.078 13.3 2.8 1.3 1 0 0 1 1 1 0 Troponin FUSC PF04632.12 EHU02000.1 - 0.048 12.2 7.4 0.077 11.5 7.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tho2 PF11262.8 EHU02000.1 - 0.049 12.8 0.6 0.081 12.1 0.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FAM184 PF15665.5 EHU02000.1 - 0.052 13.3 8.0 0.082 12.7 8.0 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B HalX PF08663.10 EHU02000.1 - 0.13 12.6 2.4 0.34 11.3 2.4 1.7 1 0 0 1 1 1 0 HalX domain LXG PF04740.12 EHU02000.1 - 0.14 11.8 2.8 0.35 10.5 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHU02000.1 - 0.19 11.5 11.1 0.31 10.8 11.1 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DHR10 PF18595.1 EHU02000.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Zn-ribbon_8 PF09723.10 EHU02000.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF1192 PF06698.11 EHU02000.1 - 0.54 10.4 5.3 3.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHU02000.1 - 0.82 8.9 3.0 1.2 8.3 3.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHU02000.1 - 2 8.0 8.1 4.3 6.8 8.1 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHU02000.1 - 4.2 7.7 8.6 8.7 6.7 8.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CREPT PF16566.5 EHU02000.1 - 5.9 7.1 8.7 2.7 8.1 5.6 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour SlyX PF04102.12 EHU02000.1 - 9.3 7.0 9.0 18 6.1 2.3 3.1 1 1 1 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHU02001.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHU02002.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU02002.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU02002.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU02002.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix Cu-oxidase_3 PF07732.15 EHU02003.1 - 1.5e-23 83.0 0.1 6.6e-23 81.0 0.1 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EHU02003.1 - 2.7e-11 43.3 0.0 5.5e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.22 EHU02003.1 - 3.1e-06 27.4 0.0 6.4e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Multicopper oxidase TAT_signal PF10518.9 EHU02003.1 - 0.02 14.7 0.2 0.02 14.7 0.2 2.0 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence Acyltransferase PF01553.21 EHU02004.1 - 3.5e-31 107.6 0.0 6.2e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase UPF0060 PF02694.15 EHU02004.1 - 0.05 13.8 0.0 0.098 12.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised BCR, YnfA/UPF0060 family DUF4191 PF13829.6 EHU02004.1 - 0.11 11.8 0.4 0.28 10.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DNA_topoisoIV PF00521.20 EHU02005.1 - 9.1e-133 443.2 0.0 1.1e-132 443.0 0.0 1.0 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 EHU02005.1 - 1.1e-15 56.8 0.0 9.2e-09 34.6 0.0 3.8 4 0 0 4 4 4 2 DNA gyrase C-terminal domain, beta-propeller Lzipper-MIP1 PF14389.6 EHU02005.1 - 0.017 15.4 2.0 0.044 14.1 2.0 1.7 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DUF4890 PF16231.5 EHU02005.1 - 0.2 12.2 2.0 0.45 11.0 2.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4890) SWIRM-assoc_1 PF16495.5 EHU02005.1 - 0.6 10.1 7.3 1.3 9.0 7.3 1.5 1 0 0 1 1 1 0 SWIRM-associated region 1 PTS_EIIA_2 PF00359.22 EHU02006.1 - 1.6e-31 109.2 0.0 1.8e-31 109.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 PTS_IIB PF02302.17 EHU02007.1 - 2.7e-17 63.3 1.1 3.1e-17 63.1 1.1 1.1 1 0 0 1 1 1 1 PTS system, Lactose/Cellobiose specific IIB subunit PTS_EIIC PF02378.18 EHU02008.1 - 1.7e-12 47.0 31.9 2.5e-11 43.2 31.9 2.2 1 1 0 1 1 1 1 Phosphotransferase system, EIIC F_bP_aldolase PF01116.20 EHU02009.1 - 4.2e-75 252.8 0.0 4.6e-75 252.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Peripla_BP_4 PF13407.6 EHU02009.1 - 0.036 13.6 0.4 0.088 12.4 0.1 1.7 2 0 0 2 2 2 0 Periplasmic binding protein domain F_bP_aldolase PF01116.20 EHU02010.1 - 6.9e-89 298.0 0.0 7.8e-89 297.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II TMP-TENI PF02581.17 EHU02010.1 - 0.031 13.6 0.0 0.27 10.5 0.0 2.3 3 0 0 3 3 3 0 Thiamine monophosphate synthase SBP_bac_3 PF00497.20 EHU02011.1 - 1.7e-40 138.8 0.0 1.9e-40 138.7 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 EHU02011.1 - 0.0032 17.7 0.2 0.082 13.1 0.0 3.0 3 1 0 3 3 3 1 Ligated ion channel L-glutamate- and glycine-binding site Phosphonate-bd PF12974.7 EHU02011.1 - 0.046 13.3 0.0 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_11 PF13531.6 EHU02011.1 - 0.075 12.8 0.5 8 6.1 0.0 2.9 1 1 2 3 3 3 0 Bacterial extracellular solute-binding protein DNA_gyraseB PF00204.25 EHU02012.1 - 1.4e-39 135.4 0.0 2.8e-39 134.4 0.0 1.5 1 0 0 1 1 1 1 DNA gyrase B DNA_gyraseB_C PF00986.21 EHU02012.1 - 1.9e-23 82.4 1.9 3e-23 81.8 0.9 1.9 2 0 0 2 2 2 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 EHU02012.1 - 5.3e-17 62.3 0.1 1.1e-16 61.3 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EHU02012.1 - 1.8e-11 44.2 0.0 4.6e-11 42.9 0.0 1.8 2 0 0 2 2 2 1 Toprim domain HATPase_c_3 PF13589.6 EHU02012.1 - 0.00075 19.3 0.1 0.0016 18.3 0.1 1.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TOPRIM_C PF16898.5 EHU02012.1 - 0.071 13.4 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 C-terminal associated domain of TOPRIM UPF0227 PF05728.12 EHU02013.1 - 1.3e-71 240.4 0.0 1.5e-71 240.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_6 PF12697.7 EHU02013.1 - 0.0055 17.3 2.9 0.0065 17.1 1.2 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EHU02013.1 - 0.011 15.1 0.1 0.038 13.3 0.0 1.7 1 1 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EHU02013.1 - 0.084 12.5 0.0 0.18 11.4 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Metallophos PF00149.28 EHU02014.1 - 6.8e-18 65.9 4.6 8.7e-18 65.6 4.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EHU02014.1 - 7.1e-07 29.6 6.5 1.3e-06 28.7 6.6 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF1249 PF06853.12 EHU02015.1 - 1.3e-40 138.1 0.4 1.5e-40 137.8 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1249) LuxS PF02664.15 EHU02015.1 - 0.069 12.8 0.0 0.12 12.1 0.0 1.4 1 1 0 1 1 1 0 S-Ribosylhomocysteinase (LuxS) NUDIX PF00293.28 EHU02016.1 - 3.4e-09 36.8 0.2 5.3e-09 36.2 0.2 1.4 1 0 0 1 1 1 1 NUDIX domain OEP PF02321.18 EHU02017.1 - 3.6e-61 206.2 36.2 3.7e-34 118.2 15.6 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein BB_PF PF18063.1 EHU02017.1 - 0.0059 16.2 1.6 0.011 15.3 1.6 1.4 1 0 0 1 1 1 1 Beta barrel Pore-forming domain Ribosomal_S5_C PF03719.15 EHU02017.1 - 0.022 14.2 0.1 0.062 12.8 0.1 1.8 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain DUF148 PF02520.17 EHU02017.1 - 0.93 9.6 8.9 25 5.1 0.4 3.8 3 0 0 3 3 3 0 Domain of unknown function DUF148 DUF1190 PF06693.11 EHU02018.1 - 4.7e-57 192.9 12.8 5.9e-57 192.6 12.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1190) SARAF PF06682.12 EHU02018.1 - 0.00023 20.9 5.7 0.00028 20.6 5.7 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis GSP_synth PF03738.14 EHU02019.1 - 9.7e-162 538.4 0.0 1.1e-161 538.2 0.0 1.0 1 0 0 1 1 1 1 Glutathionylspermidine synthase preATP-grasp TTL PF03133.15 EHU02019.1 - 0.17 11.0 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 Tubulin-tyrosine ligase family LigB PF02900.18 EHU02020.1 - 3.5e-29 101.7 0.0 4.2e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase DHBP_synthase PF00926.19 EHU02021.1 - 3e-82 274.8 1.8 3.4e-82 274.6 1.8 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase BMFP PF04380.13 EHU02022.1 - 3.8e-29 101.0 6.6 4.5e-29 100.8 6.6 1.1 1 0 0 1 1 1 1 Membrane fusogenic activity Phasin PF05597.11 EHU02022.1 - 0.039 14.0 2.1 0.38 10.7 2.1 2.0 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) ApoC-I PF04691.12 EHU02022.1 - 0.054 13.4 0.1 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) DUF3052 PF11253.8 EHU02022.1 - 0.1 12.5 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) PfkB PF00294.24 EHU02023.1 - 2e-54 185.0 0.9 3.4e-54 184.2 0.3 1.6 2 0 0 2 2 2 1 pfkB family carbohydrate kinase CTP_transf_like PF01467.26 EHU02023.1 - 3.2e-15 56.6 0.0 5.8e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like Phos_pyr_kin PF08543.12 EHU02023.1 - 1.6e-07 31.0 0.0 5.1e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.17 EHU02023.1 - 1.9e-06 27.5 1.2 1.1e-05 25.0 1.2 2.0 1 1 0 1 1 1 1 Carbohydrate kinase Propeptide_C25 PF08126.11 EHU02023.1 - 0.0082 15.3 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Propeptide_C25 Pantoate_ligase PF02569.15 EHU02023.1 - 0.031 13.5 0.2 0.18 11.0 0.1 1.9 2 0 0 2 2 2 0 Pantoate-beta-alanine ligase FAD_syn PF06574.12 EHU02023.1 - 0.049 13.5 0.0 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 FAD synthetase GlnE PF03710.15 EHU02024.1 - 9e-193 637.9 2.9 1.3e-98 329.4 0.3 2.6 2 0 0 2 2 2 2 Glutamate-ammonia ligase adenylyltransferase GlnD_UR_UTase PF08335.11 EHU02024.1 - 1.4e-57 193.9 8.2 7.2e-46 155.9 1.2 3.3 3 0 0 3 3 3 2 GlnD PII-uridylyltransferase DUF2924 PF11149.8 EHU02024.1 - 0.12 12.7 0.1 0.33 11.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) AbiEii PF08843.11 EHU02024.1 - 0.31 11.0 2.3 15 5.4 0.0 4.0 4 0 0 4 4 4 0 Nucleotidyl transferase AbiEii toxin, Type IV TA system CYTH PF01928.21 EHU02025.1 - 3.4e-30 105.3 0.0 6.2e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 CYTH domain SH3_3 PF08239.11 EHU02026.1 - 8.6e-07 29.1 0.0 1.5e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial SH3 domain TPR_MLP1_2 PF07926.12 EHU02026.1 - 4.1e-05 23.6 4.4 4.1e-05 23.6 4.4 1.7 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein FPP PF05911.11 EHU02026.1 - 0.00011 20.6 2.3 0.00014 20.3 2.3 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Ax_dynein_light PF10211.9 EHU02026.1 - 0.0022 18.0 1.6 0.0033 17.4 1.6 1.2 1 0 0 1 1 1 1 Axonemal dynein light chain FlaC_arch PF05377.11 EHU02026.1 - 0.0033 17.8 3.3 0.14 12.6 1.0 2.4 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) Seryl_tRNA_N PF02403.22 EHU02026.1 - 0.0037 17.5 6.8 0.0064 16.7 6.8 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain TolA_bind_tri PF16331.5 EHU02026.1 - 0.0049 16.9 5.2 0.019 15.0 5.2 1.9 1 1 0 1 1 1 1 TolA binding protein trimerisation Lebercilin PF15619.6 EHU02026.1 - 0.0054 16.4 3.0 0.0075 15.9 3.0 1.1 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease DUF2408 PF10303.9 EHU02026.1 - 0.0065 17.0 0.4 0.0076 16.8 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) FapA PF03961.13 EHU02026.1 - 0.0085 14.8 0.2 0.01 14.5 0.2 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A Golgin_A5 PF09787.9 EHU02026.1 - 0.0099 15.4 1.9 0.012 15.1 1.9 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 Noelin-1 PF12308.8 EHU02026.1 - 0.016 15.2 0.7 0.024 14.6 0.7 1.3 1 0 0 1 1 1 0 Neurogenesis glycoprotein DUF4407 PF14362.6 EHU02026.1 - 0.02 14.2 4.7 0.044 13.1 4.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ADIP PF11559.8 EHU02026.1 - 0.02 15.0 7.2 0.059 13.5 7.1 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3584 PF12128.8 EHU02026.1 - 0.023 12.2 2.9 0.03 11.9 2.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Bacillus_HBL PF05791.11 EHU02026.1 - 0.026 14.3 4.2 0.036 13.9 4.2 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) BAR PF03114.18 EHU02026.1 - 0.032 13.9 0.8 0.038 13.6 0.8 1.1 1 0 0 1 1 1 0 BAR domain Cep57_MT_bd PF06657.13 EHU02026.1 - 0.049 14.1 1.7 0.3 11.6 0.4 2.2 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF724 PF05266.14 EHU02026.1 - 0.05 13.4 2.0 0.069 13.0 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Spc7 PF08317.11 EHU02026.1 - 0.05 12.5 5.7 0.067 12.1 5.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein CSN5_C PF18323.1 EHU02026.1 - 0.05 14.5 1.6 0.094 13.6 1.6 1.5 1 0 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain Jnk-SapK_ap_N PF09744.9 EHU02026.1 - 0.058 13.6 2.1 0.092 13.0 2.1 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 GAS PF13851.6 EHU02026.1 - 0.064 12.6 8.0 0.19 11.1 5.5 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DivIVA PF05103.13 EHU02026.1 - 0.071 13.2 7.4 1.1 9.4 7.7 2.0 1 1 1 2 2 2 0 DivIVA protein DUF948 PF06103.11 EHU02026.1 - 0.085 13.1 1.6 0.13 12.5 1.1 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Tropomyosin_1 PF12718.7 EHU02026.1 - 0.1 12.8 5.9 0.29 11.3 5.9 1.6 1 1 0 1 1 1 0 Tropomyosin like Prominin PF05478.11 EHU02026.1 - 0.11 10.4 2.8 0.14 10.1 2.8 1.1 1 0 0 1 1 1 0 Prominin ABC_tran_CTD PF16326.5 EHU02026.1 - 0.12 12.6 1.0 0.54 10.5 1.0 2.1 1 1 0 1 1 1 0 ABC transporter C-terminal domain MbeD_MobD PF04899.12 EHU02026.1 - 0.13 12.3 1.7 0.28 11.3 0.1 2.1 1 1 1 2 2 2 0 MbeD/MobD like Lipoprotein_20 PF13942.6 EHU02026.1 - 0.14 12.1 4.0 0.36 10.7 0.5 2.1 1 1 1 2 2 2 0 YfhG lipoprotein FlxA PF14282.6 EHU02026.1 - 0.17 11.9 10.0 1.8 8.6 9.7 2.2 1 1 0 1 1 1 0 FlxA-like protein PRKG1_interact PF15898.5 EHU02026.1 - 0.17 12.8 7.1 5.3 8.0 7.1 2.2 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain HALZ PF02183.18 EHU02026.1 - 0.21 11.8 2.2 6.5 7.1 0.3 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper CLZ PF16526.5 EHU02026.1 - 0.23 11.8 2.6 0.69 10.3 0.2 2.3 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Uso1_p115_C PF04871.13 EHU02026.1 - 0.26 11.7 5.5 0.42 11.0 5.5 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF445 PF04286.12 EHU02026.1 - 0.48 10.2 5.7 0.18 11.6 3.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF1664 PF07889.12 EHU02026.1 - 0.57 10.2 5.3 0.86 9.6 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DivIC PF04977.15 EHU02026.1 - 0.76 9.6 6.4 13 5.7 2.2 2.6 1 1 1 2 2 2 0 Septum formation initiator Swi5 PF07061.11 EHU02026.1 - 0.83 9.8 5.7 4.8 7.3 0.8 2.3 1 1 1 2 2 2 0 Swi5 Fib_alpha PF08702.10 EHU02026.1 - 0.94 9.7 7.0 1.4 9.1 7.0 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Csm1_N PF18504.1 EHU02026.1 - 1.2 9.5 7.0 2.9 8.3 0.4 2.3 1 1 1 2 2 2 0 Csm1 N-terminal domain YabA PF06156.13 EHU02026.1 - 1.3 9.7 3.8 4.6 8.0 3.8 1.8 1 1 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 EHU02026.1 - 1.4 9.4 6.9 13 6.4 6.2 2.4 1 1 1 2 2 2 0 Cell division protein ZapB GIT_CC PF16559.5 EHU02026.1 - 1.5 8.8 7.8 0.64 9.9 4.1 2.1 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF16 PF01519.16 EHU02026.1 - 7.2 7.1 8.2 20 5.7 7.5 2.0 1 1 0 1 1 1 0 Protein of unknown function DUF16 YscO PF07321.12 EHU02026.1 - 7.9 6.4 9.2 13 5.7 0.3 3.0 2 1 1 3 3 3 0 Type III secretion protein YscO PolyA_pol PF01743.20 EHU02027.1 - 4.3e-18 66.0 0.0 1.9e-17 63.9 0.0 2.1 2 0 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EHU02027.1 - 5.4e-17 61.3 0.0 1.2e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A HD PF01966.22 EHU02027.1 - 1.4e-10 41.5 0.5 4.1e-10 39.9 0.1 2.0 2 0 0 2 2 2 1 HD domain BacA PF02673.18 EHU02028.1 - 1.2e-85 287.3 17.9 1.4e-85 287.1 17.9 1.0 1 0 0 1 1 1 1 Bacitracin resistance protein BacA FolB PF02152.18 EHU02029.1 - 8.7e-32 110.0 0.1 9.7e-32 109.8 0.1 1.0 1 0 0 1 1 1 1 Dihydroneopterin aldolase G3P_acyltransf PF02660.15 EHU02030.1 - 3.3e-51 173.6 8.2 3.9e-51 173.4 8.2 1.0 1 0 0 1 1 1 1 Glycerol-3-phosphate acyltransferase Peptidase_M22 PF00814.25 EHU02031.1 - 2.8e-102 342.0 0.0 3.2e-102 341.9 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 EHU02031.1 - 0.0011 18.6 0.0 0.0072 16.0 0.0 1.9 2 0 0 2 2 2 1 Carbamoyltransferase N-terminus NBD_C PF17042.5 EHU02031.1 - 0.028 14.9 0.2 0.17 12.4 0.1 2.1 2 0 0 2 2 2 0 Nucleotide-binding C-terminal domain TrwC PF08751.11 EHU02031.1 - 0.18 11.3 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 TrwC relaxase Ribosomal_S21 PF01165.20 EHU02032.1 - 6e-22 77.1 6.5 6e-22 77.1 6.5 1.9 1 1 1 2 2 2 1 Ribosomal protein S21 Toprim_N PF08275.11 EHU02033.1 - 1e-45 154.9 0.0 1.7e-45 154.2 0.0 1.3 1 0 0 1 1 1 1 DNA primase catalytic core, N-terminal domain zf-CHC2 PF01807.20 EHU02033.1 - 5.3e-41 138.4 0.1 1.2e-40 137.2 0.1 1.6 1 0 0 1 1 1 1 CHC2 zinc finger DnaG_DnaB_bind PF08278.11 EHU02033.1 - 5.5e-35 120.7 0.6 1.1e-34 119.7 0.6 1.5 1 0 0 1 1 1 1 DNA primase DnaG DnaB-binding Toprim_2 PF13155.6 EHU02033.1 - 6e-15 55.4 0.0 1.2e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Toprim-like Toprim_4 PF13662.6 EHU02033.1 - 1.9e-14 53.9 0.0 3.5e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Toprim domain DnaB_bind PF10410.9 EHU02033.1 - 2.3e-12 46.9 0.7 7.1e-12 45.3 0.0 2.3 3 0 0 3 3 3 1 DnaB-helicase binding domain of primase Toprim PF01751.22 EHU02033.1 - 2e-11 44.0 0.0 3.8e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Toprim_3 PF13362.6 EHU02033.1 - 1.2e-08 35.2 0.0 4.1e-08 33.5 0.0 1.9 2 0 0 2 2 2 1 Toprim domain Sigma70_ner PF04546.13 EHU02035.1 - 4.3e-74 248.8 3.1 4.3e-74 248.8 3.1 2.8 3 0 0 3 3 3 1 Sigma-70, non-essential region Sigma70_r1_1 PF03979.14 EHU02035.1 - 9.5e-31 105.7 4.9 9.5e-31 105.7 4.9 3.2 3 0 0 3 3 3 1 Sigma-70 factor, region 1.1 Sigma70_r3 PF04539.16 EHU02035.1 - 3.1e-29 100.9 6.7 3.8e-29 100.6 1.0 3.5 3 0 0 3 3 3 1 Sigma-70 region 3 Sigma70_r2 PF04542.14 EHU02035.1 - 7.4e-22 76.9 0.3 1.8e-21 75.7 0.3 1.7 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 EHU02035.1 - 1e-18 66.6 0.8 1e-18 66.6 0.8 3.4 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_r1_2 PF00140.20 EHU02035.1 - 2.5e-13 49.8 0.3 1.8e-12 47.0 0.1 2.5 2 0 0 2 2 2 1 Sigma-70 factor, region 1.2 DNA_ligase_A_N PF04675.14 EHU02035.1 - 0.011 16.0 0.8 0.011 16.0 0.8 2.4 2 1 1 3 3 3 0 DNA ligase N terminus DUF2610 PF11020.8 EHU02035.1 - 0.13 12.2 0.1 2.7 7.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2610) Sun2_CC2 PF18580.1 EHU02035.1 - 0.16 12.2 4.1 1.2 9.4 0.1 3.1 3 0 0 3 3 2 0 SUN2 coiled coil domain 2 Eclosion PF04736.12 EHU02035.1 - 0.17 11.6 0.1 0.33 10.7 0.1 1.4 1 0 0 1 1 1 0 Eclosion hormone HTH_25 PF13413.6 EHU02035.1 - 0.66 9.9 3.2 30 4.6 0.0 3.5 3 0 0 3 3 3 0 Helix-turn-helix domain FlgN PF05130.12 EHU02035.1 - 0.83 10.2 5.2 6.8 7.2 0.4 3.4 3 1 0 3 3 3 0 FlgN protein DUF4611 PF15387.6 EHU02035.1 - 4.7 7.5 11.4 0.56 10.5 2.4 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) UDG PF03167.19 EHU02036.1 - 8.6e-23 81.0 0.0 9.5e-23 80.9 0.0 1.0 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF3828 PF12883.7 EHU02037.1 - 1.7e-10 41.3 0.0 2.4e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3828) Phage_cap_P2 PF05125.12 EHU02039.1 - 2.2e-103 345.7 0.0 2.5e-103 345.5 0.0 1.0 1 0 0 1 1 1 1 Phage major capsid protein, P2 family YscO-like PF16789.5 EHU02041.1 - 0.032 14.3 2.2 0.049 13.7 2.2 1.2 1 0 0 1 1 1 0 YscO-like protein DUF948 PF06103.11 EHU02041.1 - 0.11 12.7 0.1 1.5 9.1 0.0 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) NolV PF06635.12 EHU02041.1 - 0.25 10.7 4.8 0.058 12.8 0.9 1.9 1 1 1 2 2 2 0 Nodulation protein NolV Phage_integrase PF00589.22 EHU02043.1 - 8.7e-20 71.2 0.8 4.1e-17 62.5 0.8 2.5 1 1 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 EHU02043.1 - 0.065 13.5 0.1 0.22 11.8 0.1 1.9 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Zn_Tnp_IS91 PF14319.6 EHU02044.1 - 0.13 12.3 1.6 0.18 11.9 1.6 1.3 1 0 0 1 1 1 0 Transposase zinc-binding domain Phage_GPA PF05840.13 EHU02045.1 - 1.8e-116 388.7 0.3 2.2e-116 388.4 0.3 1.1 1 0 0 1 1 1 1 Bacteriophage replication gene A protein (GPA) zf-dskA_traR PF01258.17 EHU02047.1 - 6.9e-11 41.9 6.7 1.2e-10 41.2 6.7 1.3 1 0 0 1 1 1 1 Prokaryotic dksA/traR C4-type zinc finger DZR PF12773.7 EHU02047.1 - 3.8e-05 23.6 1.8 5.4e-05 23.1 1.8 1.2 1 0 0 1 1 1 1 Double zinc ribbon C1_1 PF00130.22 EHU02047.1 - 0.008 16.0 0.5 0.011 15.6 0.5 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2732 PF10809.8 EHU02048.1 - 5.6e-18 64.6 3.7 6.5e-18 64.4 3.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2732) SCHIP-1 PF10148.9 EHU02048.1 - 0.046 13.3 0.2 0.047 13.3 0.2 1.0 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 HTH_27 PF13463.6 EHU02048.1 - 0.068 13.7 0.1 0.077 13.5 0.1 1.1 1 0 0 1 1 1 0 Winged helix DNA-binding domain Phage_CI_C PF16452.5 EHU02050.1 - 6.8e-31 106.6 0.0 1e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 Bacteriophage CI repressor C-terminal domain Phage_CI_repr PF07022.13 EHU02050.1 - 7e-25 86.9 0.0 1e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Bacteriophage CI repressor helix-turn-helix domain HTH_19 PF12844.7 EHU02050.1 - 0.063 13.3 0.0 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_psq PF05225.16 EHU02050.1 - 0.12 12.1 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Phage_CII PF05269.11 EHU02050.1 - 0.17 12.1 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage CII protein MCPsignal PF00015.21 EHU02051.1 - 5.8e-46 156.4 18.3 5.8e-46 156.4 18.3 3.4 3 1 1 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain 4HB_MCP_1 PF12729.7 EHU02051.1 - 4.9e-14 52.3 1.0 4.9e-14 52.3 1.0 2.8 2 1 0 2 2 2 1 Four helix bundle sensory module for signal transduction Fez1 PF06818.15 EHU02051.1 - 0.0015 19.0 2.6 0.0015 19.0 2.6 2.6 3 0 0 3 3 3 1 Fez1 DAHP_snth_FXD PF18152.1 EHU02051.1 - 0.051 13.4 1.2 0.14 12.0 1.2 1.9 1 0 0 1 1 1 0 DAHP synthase ferredoxin-like domain COG2 PF06148.11 EHU02051.1 - 0.15 12.1 7.1 0.093 12.8 1.5 3.1 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4200 PF13863.6 EHU02051.1 - 0.33 11.4 4.2 0.13 12.7 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) IFT57 PF10498.9 EHU02051.1 - 3.3 6.6 8.2 0.3 10.0 3.4 1.7 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Acid_phosphat_B PF03767.14 EHU02052.1 - 8.9e-63 212.0 0.3 1.1e-62 211.7 0.3 1.0 1 0 0 1 1 1 1 HAD superfamily, subfamily IIIB (Acid phosphatase) Hydrolase_6 PF13344.6 EHU02052.1 - 3.6e-05 23.8 0.0 7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EHU02052.1 - 0.0031 17.8 0.1 0.0096 16.2 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EHU02052.1 - 0.037 14.1 0.2 0.74 9.9 0.0 2.2 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Trp_ring PF18669.1 EHU02052.1 - 0.53 10.5 3.9 0.32 11.2 0.6 2.4 3 0 0 3 3 3 0 Trimeric autotransporter adhesin Trp ring domain Pro_CA PF00484.19 EHU02053.1 - 5.4e-43 147.0 0.0 6.4e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Sulfate_transp PF00916.20 EHU02054.1 - 3.7e-52 177.4 25.9 3.7e-52 177.4 25.9 1.5 1 1 0 1 1 1 1 Sulfate permease family MFS_MOT1 PF16983.5 EHU02054.1 - 1.4e-06 28.7 5.1 1.4e-06 28.7 5.1 4.4 3 2 0 3 3 3 1 Molybdate transporter of MFS superfamily MitoNEET_N PF10660.9 EHU02054.1 - 0.19 11.8 1.0 0.98 9.5 0.1 2.7 2 0 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus GGDEF PF00990.21 EHU02055.1 - 6.4e-36 123.5 0.0 9.1e-36 123.0 0.0 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Dala_Dala_lig_C PF07478.13 EHU02056.1 - 3.5e-77 258.6 0.0 4.6e-77 258.2 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 EHU02056.1 - 7.4e-30 103.5 0.0 1.2e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase N-terminus ATP-grasp PF02222.22 EHU02056.1 - 6.3e-11 42.1 0.0 1.3e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 EHU02056.1 - 1.6e-05 24.5 0.0 2.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 EHU02056.1 - 0.00027 20.6 0.5 0.0076 15.9 0.5 2.6 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EHU02056.1 - 0.00035 20.6 0.0 0.00071 19.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 EHU02056.1 - 0.00043 19.6 0.0 0.47 9.7 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp HTH_Tnp_1 PF01527.20 EHU02057.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU02057.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU02057.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU02057.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHU02058.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHU02059.1 - 1.2e-97 326.8 4.4 3.8e-97 325.1 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU02059.1 - 3.3e-16 59.2 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU02059.1 - 8.1e-15 55.0 1.3 1.9e-14 53.8 1.3 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU02059.1 - 8.7e-11 42.4 9.0 1.9e-10 41.4 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Exonuc_VII_L PF02601.15 EHU02059.1 - 0.03 13.9 1.8 0.04 13.5 0.6 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Phage_HK97_TLTM PF06120.11 EHU02059.1 - 0.033 13.4 0.8 0.062 12.5 0.8 1.4 1 0 0 1 1 1 0 Tail length tape measure protein UME PF08064.13 EHU02059.1 - 0.037 13.9 0.4 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain FUSC PF04632.12 EHU02059.1 - 0.063 11.8 7.7 0.1 11.1 7.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Csm1_N PF18504.1 EHU02059.1 - 0.13 12.6 3.4 0.86 10.0 0.2 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Tho2 PF11262.8 EHU02059.1 - 0.17 11.0 0.3 0.28 10.4 0.3 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DHR10 PF18595.1 EHU02059.1 - 0.18 11.9 10.2 0.31 11.1 10.2 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain ERM PF00769.19 EHU02059.1 - 0.28 11.0 10.4 0.45 10.3 10.4 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family LXG PF04740.12 EHU02059.1 - 0.28 10.9 2.4 0.86 9.3 0.3 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily HHH_8 PF14716.6 EHU02059.1 - 0.34 11.3 4.0 0.56 10.6 1.9 2.4 2 1 0 2 2 2 0 Helix-hairpin-helix domain TSNAXIP1_N PF15739.5 EHU02059.1 - 0.46 10.9 3.2 0.99 9.8 3.2 1.5 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus FAM184 PF15665.5 EHU02059.1 - 0.5 10.1 7.3 0.78 9.5 7.3 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B TMPIT PF07851.13 EHU02059.1 - 0.78 8.9 2.7 1.2 8.4 2.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein CREPT PF16566.5 EHU02059.1 - 2.3 8.4 8.3 1.1 9.5 5.2 1.8 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour HAUS-augmin3 PF14932.6 EHU02059.1 - 2.9 7.4 7.6 6.7 6.2 7.6 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 SlyX PF04102.12 EHU02059.1 - 8.3 7.1 8.7 17 6.1 2.1 3.0 1 1 1 2 2 2 0 SlyX EAL PF00563.20 EHU02060.1 - 1.8e-61 207.7 0.0 4.1e-61 206.5 0.0 1.6 2 0 0 2 2 2 1 EAL domain GAF_2 PF13185.6 EHU02060.1 - 2.5e-09 37.5 0.0 9.8e-09 35.6 0.0 2.0 2 0 0 2 2 2 1 GAF domain GAF PF01590.26 EHU02060.1 - 3.8e-09 37.3 0.0 1.1e-08 35.8 0.0 1.8 1 0 0 1 1 1 1 GAF domain GGDEF PF00990.21 EHU02060.1 - 0.00098 18.9 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain MCPsignal PF00015.21 EHU02061.1 - 6.2e-44 149.8 17.2 6.2e-44 149.8 17.2 2.9 1 1 1 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 EHU02061.1 - 0.00056 20.2 1.4 0.0074 16.6 0.0 3.5 3 0 0 3 3 3 1 HAMP domain HTH_31 PF13560.6 EHU02062.1 - 0.0014 19.0 0.5 0.0018 18.6 0.5 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 EHU02062.1 - 0.031 14.3 0.1 0.05 13.7 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix PAS_9 PF13426.7 EHU02063.1 - 5.6e-15 55.5 0.0 9.5e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EHU02063.1 - 3.1e-14 52.9 0.0 5.1e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EHU02063.1 - 9e-13 48.4 0.3 1.8e-11 44.3 0.0 2.8 2 1 1 3 3 3 1 PAS fold GAF PF01590.26 EHU02063.1 - 4.4e-10 40.3 0.0 7.3e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 GAF domain PAS_8 PF13188.7 EHU02063.1 - 1.2e-08 34.8 0.0 6.3e-08 32.5 0.0 2.3 2 0 0 2 2 2 1 PAS domain GGDEF PF00990.21 EHU02063.1 - 4.7e-06 26.5 0.1 9.4e-06 25.5 0.1 1.5 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_3 PF08447.12 EHU02063.1 - 0.066 13.5 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 PAS fold DUF1040 PF06288.13 EHU02063.1 - 0.067 13.6 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1040) DDE_3 PF13358.6 EHU02064.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHU02064.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHU02064.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHU02064.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHU02064.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHU02064.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHU02064.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHU02064.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 Patatin PF01734.22 EHU02065.1 - 1.3e-18 68.0 1.2 1.6e-17 64.4 1.2 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase Lys-AminoMut_A PF09043.11 EHU02065.1 - 0.24 9.8 0.0 0.31 9.4 0.0 1.1 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit TatD_DNase PF01026.21 EHU02066.1 - 1.9e-65 220.8 0.0 2.2e-65 220.6 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Asparaginase_C PF17763.1 EHU02066.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain DUF3040 PF11239.8 EHU02066.1 - 0.14 12.4 4.0 4.9 7.5 0.5 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) DeoC PF01791.9 EHU02067.1 - 5e-48 163.8 1.3 5.6e-48 163.6 1.3 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase Glycos_transf_3 PF00591.21 EHU02068.1 - 5e-51 173.7 0.9 7.4e-51 173.2 0.9 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain PYNP_C PF07831.13 EHU02068.1 - 4.7e-24 83.8 0.3 9.6e-24 82.8 0.3 1.6 1 0 0 1 1 1 1 Pyrimidine nucleoside phosphorylase C-terminal domain Glycos_trans_3N PF02885.17 EHU02068.1 - 5.8e-19 67.7 0.1 1.3e-18 66.6 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Metalloenzyme PF01676.18 EHU02069.1 - 3.7e-35 121.5 0.0 6.5e-35 120.7 0.0 1.4 1 1 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 EHU02069.1 - 0.067 12.8 0.0 0.096 12.2 0.0 1.2 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase PNP_UDP_1 PF01048.20 EHU02070.1 - 4.3e-40 137.4 1.7 5.1e-40 137.2 1.7 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily YidD PF01809.18 EHU02070.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative membrane protein insertion efficiency factor Transpeptidase PF00905.22 EHU02071.1 - 1.3e-69 234.8 0.0 1.7e-69 234.4 0.0 1.1 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain PBP_dimer PF03717.15 EHU02071.1 - 2.2e-45 155.2 0.0 5.1e-45 154.0 0.0 1.6 2 0 0 2 2 2 1 Penicillin-binding Protein dimerisation domain DDE_Tnp_IS66 PF03050.14 EHU02072.1 - 1.1e-97 326.9 4.5 3.8e-97 325.1 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU02072.1 - 3.2e-16 59.3 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU02072.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU02072.1 - 8.7e-11 42.4 9.0 1.9e-10 41.4 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Phage_HK97_TLTM PF06120.11 EHU02072.1 - 0.011 15.0 0.8 0.021 14.0 0.8 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHU02072.1 - 0.02 15.2 4.2 0.084 13.2 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain UME PF08064.13 EHU02072.1 - 0.033 14.1 0.3 20 5.1 0.0 3.1 2 1 1 3 3 3 0 UME (NUC010) domain Exonuc_VII_L PF02601.15 EHU02072.1 - 0.039 13.5 2.7 0.04 13.5 1.0 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Troponin PF00992.20 EHU02072.1 - 0.044 14.1 2.8 0.078 13.3 2.8 1.3 1 0 0 1 1 1 0 Troponin FUSC PF04632.12 EHU02072.1 - 0.048 12.2 7.4 0.077 11.5 7.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tho2 PF11262.8 EHU02072.1 - 0.049 12.8 0.6 0.081 12.1 0.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FAM184 PF15665.5 EHU02072.1 - 0.052 13.3 8.0 0.082 12.7 8.0 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B HalX PF08663.10 EHU02072.1 - 0.13 12.6 2.4 0.34 11.3 2.4 1.7 1 0 0 1 1 1 0 HalX domain LXG PF04740.12 EHU02072.1 - 0.14 11.8 2.8 0.35 10.5 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHU02072.1 - 0.19 11.5 11.1 0.31 10.8 11.1 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DHR10 PF18595.1 EHU02072.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Zn-ribbon_8 PF09723.10 EHU02072.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF1192 PF06698.11 EHU02072.1 - 0.54 10.4 5.3 3.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHU02072.1 - 0.82 8.9 3.0 1.2 8.3 3.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHU02072.1 - 2 8.0 8.1 4.3 6.8 8.1 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHU02072.1 - 4.2 7.7 8.6 8.7 6.7 8.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CREPT PF16566.5 EHU02072.1 - 5.9 7.1 8.7 2.7 8.1 5.6 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour SlyX PF04102.12 EHU02072.1 - 9.3 7.0 9.0 18 6.1 2.3 3.0 1 1 1 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHU02073.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHU02074.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU02074.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU02074.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU02074.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix DUF1987 PF09345.10 EHU02075.1 - 1.2e-39 134.7 0.1 1.4e-39 134.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1987) Helicase_IV_N PF12462.8 EHU02075.1 - 0.021 14.8 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal DUF4874 PF16173.5 EHU02075.1 - 0.058 13.1 0.0 0.062 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4874) FAA_hydro_N_2 PF18288.1 EHU02075.1 - 0.077 13.4 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal domain 2 SpoIIE PF07228.12 EHU02077.1 - 7.4e-25 88.0 0.0 1.1e-24 87.4 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) CBS PF00571.28 EHU02077.1 - 1.3e-07 31.9 0.1 0.0018 18.7 0.0 2.3 2 0 0 2 2 2 2 CBS domain Pectate_lyase_3 PF12708.7 EHU02079.1 - 8.5e-08 32.3 3.5 4.6e-07 29.9 3.4 2.1 1 1 0 1 1 1 1 Pectate lyase superfamily protein Sugar_tr PF00083.24 EHU02081.1 - 5.2e-26 91.5 27.5 1.1e-16 60.8 6.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EHU02081.1 - 5.1e-24 84.9 47.3 6.4e-17 61.5 19.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HKR_ArcB_TM PF18415.1 EHU02081.1 - 1.6 9.6 8.3 15 6.4 0.5 3.7 3 0 0 3 3 3 0 Histidine kinase receptor ArcB trans-membrane domain Peptidase_M20 PF01546.28 EHU02082.1 - 1.1e-23 84.1 0.0 1.3e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EHU02082.1 - 3.6e-11 42.9 0.0 8.3e-11 41.8 0.0 1.6 1 1 0 1 1 1 1 Peptidase dimerisation domain WYL PF13280.6 EHU02082.1 - 0.2 11.7 0.6 17 5.4 0.0 3.0 2 1 1 3 3 3 0 WYL domain KptA_kDCL PF18176.1 EHU02083.1 - 0.13 12.1 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 KptA in kinetoplastid DICER domain DUF4432 PF14486.6 EHU02084.1 - 2.2e-108 361.6 0.0 2.6e-108 361.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4432) DUF4232 PF14016.6 EHU02084.1 - 0.042 14.0 0.1 0.2 11.8 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4232) DUF5045 PF16464.5 EHU02084.1 - 0.14 12.5 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5045) 2H-phosphodiest PF08975.10 EHU02086.1 - 1e-34 118.9 0.0 2.1e-34 118.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1868) 2_5_RNA_ligase2 PF13563.6 EHU02086.1 - 0.00076 19.4 0.1 0.0014 18.5 0.1 1.6 1 1 1 2 2 2 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 EHU02086.1 - 0.049 13.8 0.0 0.25 11.6 0.1 2.0 2 0 0 2 2 2 0 LigT like Phosphoesterase FtsQ PF03799.15 EHU02086.1 - 0.13 13.0 0.0 5.4 7.9 0.0 2.2 2 0 0 2 2 2 0 Cell division protein FtsQ TAT_signal PF10518.9 EHU02086.1 - 0.88 9.5 3.4 1.8 8.6 3.4 1.5 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence MCPsignal PF00015.21 EHU02087.1 - 6.2e-33 114.0 10.2 6.2e-33 114.0 10.2 2.8 2 1 1 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain PAS_9 PF13426.7 EHU02087.1 - 2e-29 101.9 0.0 2.3e-13 50.3 0.0 2.9 3 0 0 3 3 3 2 PAS domain PAS_3 PF08447.12 EHU02087.1 - 9.7e-24 83.5 0.2 8.7e-13 48.4 0.1 2.5 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 EHU02087.1 - 7.3e-23 80.9 0.0 1.7e-11 44.3 0.0 2.8 3 0 0 3 3 3 2 PAS fold PAS PF00989.25 EHU02087.1 - 1.8e-12 47.2 0.0 1.2e-05 25.3 0.0 2.9 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.7 EHU02087.1 - 2.3e-06 27.5 0.0 0.023 14.7 0.0 2.5 2 0 0 2 2 2 2 PAS domain Cache_3-Cache_2 PF17201.4 EHU02087.1 - 0.0044 16.3 0.0 0.43 9.8 0.0 2.8 3 0 0 3 3 3 1 Cache 3/Cache 2 fusion domain DUF948 PF06103.11 EHU02087.1 - 0.018 15.3 10.5 0.98 9.7 0.5 3.9 3 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Halogen_Hydrol PF10112.9 EHU02087.1 - 0.038 14.0 0.0 0.097 12.7 0.0 1.6 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Laminin_II PF06009.12 EHU02087.1 - 0.067 13.2 11.6 0.48 10.4 1.8 3.7 3 1 0 3 3 3 0 Laminin Domain II Csm1_N PF18504.1 EHU02087.1 - 0.18 12.1 2.7 0.42 11.0 1.0 2.4 2 1 0 2 2 2 0 Csm1 N-terminal domain LOH1CR12 PF10158.9 EHU02087.1 - 0.23 11.5 1.9 0.4 10.7 0.2 2.3 2 0 0 2 2 2 0 Tumour suppressor protein FtsA PF14450.6 EHU02087.1 - 1.5 9.3 5.5 6.2 7.3 5.7 2.0 2 1 0 2 2 2 0 Cell division protein FtsA Baculo_PEP_C PF04513.12 EHU02087.1 - 2.4 8.2 11.9 0.51 10.4 6.1 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 EHU02087.1 - 3.4 7.7 9.9 0.46 10.5 1.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) MCPsignal PF00015.21 EHU02088.1 - 6.3e-31 107.5 15.8 6.3e-31 107.5 15.8 2.7 2 1 1 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain PAS_9 PF13426.7 EHU02088.1 - 5.3e-25 87.7 0.1 1.1e-11 44.9 0.0 2.8 3 0 0 3 3 3 2 PAS domain PAS_3 PF08447.12 EHU02088.1 - 1.9e-24 85.8 0.0 6e-13 48.9 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 EHU02088.1 - 7.4e-20 71.2 0.0 3.8e-08 33.5 0.0 3.0 3 0 0 3 3 3 2 PAS fold PAS PF00989.25 EHU02088.1 - 1e-08 35.1 0.0 0.00066 19.7 0.0 3.2 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.7 EHU02088.1 - 0.026 14.5 0.0 0.83 9.8 0.0 2.4 2 0 0 2 2 2 0 PAS domain Laminin_II PF06009.12 EHU02088.1 - 0.032 14.2 10.3 2.7 8.0 0.4 3.3 3 0 0 3 3 3 0 Laminin Domain II Vip3A_N PF12495.8 EHU02088.1 - 0.055 13.4 5.2 0.15 12.0 0.1 2.9 3 0 0 3 3 3 0 Vegetative insecticide protein 3A N terminal Polyoma_coat2 PF00761.20 EHU02088.1 - 0.071 12.8 4.1 0.32 10.7 3.3 2.0 2 0 0 2 2 2 0 Polyomavirus coat protein BLOC1_2 PF10046.9 EHU02088.1 - 0.085 13.2 6.6 3.9 7.9 0.1 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FimH_man-bind PF09160.10 EHU02088.1 - 0.11 12.2 0.6 15 5.3 0.0 3.3 2 1 1 3 3 3 0 FimH, mannose binding DUF5100 PF17029.5 EHU02088.1 - 0.38 10.6 3.6 11 5.8 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5100) DUF948 PF06103.11 EHU02088.1 - 0.5 10.6 15.8 0.99 9.7 0.6 3.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) LOH1CR12 PF10158.9 EHU02088.1 - 1 9.4 6.6 0.61 10.1 0.1 2.8 3 0 0 3 3 3 0 Tumour suppressor protein NPV_P10 PF05531.12 EHU02088.1 - 1.2 9.6 11.1 4.2 7.9 0.4 3.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein KASH_CCD PF14662.6 EHU02088.1 - 1.5 8.6 5.0 0.79 9.5 0.1 2.4 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH DUF1664 PF07889.12 EHU02088.1 - 3.3 7.8 12.9 1.7 8.7 1.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) T7SS_ESX_EspC PF10824.8 EHU02088.1 - 6.1 7.4 10.4 5.7 7.5 0.6 2.8 1 1 2 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm 4HBT_2 PF13279.6 EHU02089.1 - 0.00017 22.1 0.0 0.0002 21.9 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily MaoC_dehydrat_N PF13452.6 EHU02089.1 - 0.017 15.3 0.0 0.024 14.8 0.0 1.3 1 0 0 1 1 1 0 N-terminal half of MaoC dehydratase MCPsignal PF00015.21 EHU02090.1 - 7.8e-51 172.3 30.8 1.6e-50 171.3 17.5 2.6 1 1 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain CHASE3 PF05227.13 EHU02090.1 - 6.2e-33 113.6 0.3 6.2e-33 113.6 0.3 4.0 3 1 1 4 4 4 2 CHASE3 domain Mod_r PF07200.13 EHU02090.1 - 0.067 13.3 8.5 1.1 9.3 2.2 3.1 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Vps23_core PF09454.10 EHU02090.1 - 0.24 11.4 1.6 4.5 7.3 0.1 3.0 2 1 1 3 3 3 0 Vps23 core domain IFT57 PF10498.9 EHU02090.1 - 3.6 6.5 8.7 0.31 9.9 1.5 2.3 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Spc7 PF08317.11 EHU02090.1 - 5.5 5.8 8.9 2.2 7.1 2.1 2.6 3 0 0 3 3 3 0 Spc7 kinetochore protein NACHT_N PF17100.5 EHU02090.1 - 7.8 6.3 12.5 9.7 6.0 2.1 2.5 2 0 0 2 2 2 0 N-terminal domain of NWD NACHT-NTPase GGDEF PF00990.21 EHU02092.1 - 1.8e-30 105.8 0.0 2.8e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_3 PF08447.12 EHU02092.1 - 3.9e-19 68.7 0.2 8.4e-19 67.7 0.1 1.7 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 EHU02092.1 - 0.00013 22.2 0.0 0.00097 19.4 0.0 2.2 2 0 0 2 2 2 1 PAS domain Abhydrolase_1 PF00561.20 EHU02093.1 - 1.5e-29 103.4 0.1 3.8e-27 95.6 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EHU02093.1 - 2e-22 79.6 0.2 3.2e-14 52.8 0.1 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EHU02093.1 - 1.1e-19 71.9 0.3 1.4e-19 71.6 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EHU02093.1 - 2.4e-08 33.7 0.1 8.5e-06 25.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 EHU02093.1 - 3e-05 23.7 0.1 0.00067 19.3 0.0 2.4 2 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 EHU02093.1 - 3.9e-05 23.6 0.0 0.021 14.6 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 EHU02093.1 - 9.6e-05 22.1 0.0 0.25 10.9 0.0 2.2 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_4 PF08386.10 EHU02093.1 - 0.00023 21.2 0.0 0.00035 20.7 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein DUF915 PF06028.11 EHU02093.1 - 0.0011 18.4 0.1 0.0067 15.8 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_5 PF12695.7 EHU02093.1 - 0.0053 16.5 0.0 1.1 9.0 0.0 2.6 3 0 0 3 3 3 1 Alpha/beta hydrolase family FSH1 PF03959.13 EHU02093.1 - 0.027 14.1 0.0 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Ndr PF03096.14 EHU02093.1 - 0.085 11.5 0.0 0.12 11.0 0.0 1.3 1 1 0 1 1 1 0 Ndr family KGG PF10685.9 EHU02094.1 - 1.4e-17 63.4 11.8 1.8e-09 37.6 5.3 2.1 2 0 0 2 2 2 2 Stress-induced bacterial acidophilic repeat motif DUF892 PF05974.12 EHU02095.1 - 2.5e-54 183.6 7.8 2.9e-54 183.4 7.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF892) RPT PF13446.6 EHU02095.1 - 0.019 14.9 0.2 0.39 10.7 0.0 2.6 3 0 0 3 3 3 0 A repeated domain in UCH-protein FumaraseC_C PF10415.9 EHU02095.1 - 0.021 15.3 0.7 0.16 12.4 0.1 2.4 2 0 0 2 2 2 0 Fumarase C C-terminus Sec20 PF03908.13 EHU02095.1 - 0.042 13.8 0.4 0.35 10.8 0.0 2.3 2 1 0 2 2 2 0 Sec20 Rubrerythrin PF02915.17 EHU02095.1 - 0.053 13.9 2.6 0.14 12.6 0.5 2.0 1 1 1 2 2 2 0 Rubrerythrin DUF892 PF05974.12 EHU02096.1 - 1.5e-48 164.9 4.8 1.6e-48 164.7 4.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF892) COQ7 PF03232.13 EHU02096.1 - 0.01 15.7 2.1 0.02 14.7 2.1 1.5 1 1 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 DUF2383 PF09537.10 EHU02096.1 - 0.011 16.1 0.6 0.035 14.5 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) HrpJ PF07201.11 EHU02096.1 - 0.015 15.6 1.3 0.025 14.9 1.3 1.3 1 0 0 1 1 1 0 HrpJ-like domain Rubrerythrin PF02915.17 EHU02096.1 - 0.022 15.2 0.2 0.048 14.1 0.2 1.5 1 1 0 1 1 1 0 Rubrerythrin Ferritin PF00210.24 EHU02096.1 - 0.029 14.3 4.5 0.13 12.2 2.1 2.1 1 1 1 2 2 2 0 Ferritin-like domain DUF4164 PF13747.6 EHU02096.1 - 0.07 13.4 0.5 0.12 12.7 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Trehalase PF01204.18 EHU02097.1 - 2.4e-154 515.0 0.2 3.3e-154 514.5 0.2 1.2 1 0 0 1 1 1 1 Trehalase DUF346 PF03984.13 EHU02097.1 - 0.015 15.0 0.3 0.075 12.8 0.0 2.2 2 0 0 2 2 2 0 Repeat of unknown function (DUF346) Acetyltransf_1 PF00583.25 EHU02098.1 - 2.3e-15 56.8 0.0 2.8e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EHU02098.1 - 1.9e-12 47.2 0.0 2.4e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EHU02098.1 - 3.2e-09 37.1 0.0 4.5e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EHU02098.1 - 3.9e-07 30.2 0.0 5.1e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EHU02098.1 - 2.9e-05 24.0 0.0 4.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EHU02098.1 - 6.7e-05 23.6 0.0 8.2e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EHU02098.1 - 0.0012 19.0 0.0 0.0014 18.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EHU02098.1 - 0.0015 18.0 0.0 0.0045 16.5 0.0 1.7 1 1 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_CG PF14542.6 EHU02098.1 - 0.0019 18.3 0.0 0.0046 17.0 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase HTH_20 PF12840.7 EHU02099.1 - 4.8e-10 39.3 0.7 1.5e-09 37.8 0.2 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_5 PF01022.20 EHU02099.1 - 1.6e-06 27.9 0.0 2.9e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_IclR PF09339.10 EHU02099.1 - 0.0004 20.1 0.1 0.001 18.8 0.1 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 EHU02099.1 - 0.015 15.2 0.0 0.047 13.6 0.0 1.8 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.6 EHU02099.1 - 0.023 14.2 0.0 0.045 13.3 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Fe_dep_repress PF01325.19 EHU02099.1 - 0.062 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain MarR PF01047.22 EHU02099.1 - 0.073 13.0 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 MarR family ACT PF01842.25 EHU02100.1 - 3.2e-07 30.0 0.1 0.02 14.7 0.0 2.6 2 1 0 2 2 2 2 ACT domain ACT_7 PF13840.6 EHU02100.1 - 0.037 13.8 0.0 0.24 11.2 0.0 2.0 2 0 0 2 2 2 0 ACT domain ACT_4 PF13291.6 EHU02100.1 - 0.15 12.6 0.0 3.2 8.4 0.0 2.3 2 0 0 2 2 2 0 ACT domain ABM PF03992.16 EHU02101.1 - 7.2e-14 51.7 0.4 9.5e-14 51.3 0.4 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase NAD_binding_10 PF13460.6 EHU02102.1 - 4.2e-22 78.9 5.8 7.1e-22 78.2 5.8 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EHU02102.1 - 9.1e-20 71.2 0.5 1.3e-19 70.7 0.5 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 EHU02102.1 - 3e-05 23.1 0.0 6.9e-05 22.0 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EHU02102.1 - 0.00052 19.5 0.3 0.0012 18.4 0.3 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EHU02102.1 - 0.001 18.3 3.4 0.25 10.4 0.1 2.4 1 1 1 2 2 2 2 RmlD substrate binding domain NAD_binding_4 PF07993.12 EHU02102.1 - 0.0023 17.2 0.1 0.0034 16.6 0.1 1.3 1 0 0 1 1 1 1 Male sterility protein KR PF08659.10 EHU02102.1 - 0.0039 17.1 0.2 0.0039 17.1 0.2 2.3 2 1 1 3 3 3 1 KR domain DapB_N PF01113.20 EHU02102.1 - 0.0083 16.2 0.1 0.014 15.5 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.18 EHU02102.1 - 0.022 15.0 0.2 0.054 13.8 0.2 1.8 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 EHU02102.1 - 0.033 14.2 0.2 0.059 13.4 0.2 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HxlR PF01638.17 EHU02103.1 - 4.6e-27 93.7 0.1 5.8e-27 93.4 0.1 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_34 PF13601.6 EHU02103.1 - 0.0001 22.4 0.0 0.00014 21.9 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_5 PF01022.20 EHU02103.1 - 0.013 15.4 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_12 PF08461.10 EHU02103.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain MarR_2 PF12802.7 EHU02103.1 - 0.048 13.6 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_20 PF12840.7 EHU02103.1 - 0.11 12.6 0.2 0.23 11.5 0.1 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain Cyt_bd_oxida_II PF02322.15 EHU02105.1 - 2.7e-99 332.4 29.6 3.1e-99 332.2 29.6 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II PalH PF08733.10 EHU02105.1 - 0.097 11.7 2.1 0.15 11.0 2.1 1.3 1 0 0 1 1 1 0 PalH/RIM21 DUF2474 PF10617.9 EHU02106.1 - 4.4e-21 74.4 10.4 5e-21 74.3 10.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2474) DUF1129 PF06570.11 EHU02106.1 - 0.04 13.4 0.8 0.043 13.3 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) HTH_18 PF12833.7 EHU02107.1 - 5.1e-19 68.3 0.9 8.8e-19 67.6 0.9 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 EHU02107.1 - 8.8e-11 41.6 0.1 3.2e-06 27.1 0.0 2.5 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family GyrI-like PF06445.15 EHU02107.1 - 0.0013 19.1 0.0 0.002 18.4 0.0 1.2 1 0 0 1 1 1 1 GyrI-like small molecule binding domain Cass2 PF14526.6 EHU02107.1 - 0.0017 18.6 0.0 0.0027 17.9 0.0 1.3 1 0 0 1 1 1 1 Integron-associated effector binding protein SIP PF04954.13 EHU02109.1 - 6.3e-19 68.6 0.3 8.2e-19 68.3 0.3 1.2 1 0 0 1 1 1 1 Siderophore-interacting protein FAD_binding_9 PF08021.11 EHU02109.1 - 2.1e-15 57.0 0.0 3.2e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain PadR PF03551.14 EHU02110.1 - 7.5e-15 54.7 0.0 1.2e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family Rdx PF10262.9 EHU02111.1 - 2.5e-32 110.9 0.0 3e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Rdx family ADH_zinc_N PF00107.26 EHU02112.1 - 1.2e-09 38.3 0.0 1.8e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EHU02112.1 - 9.1e-05 23.5 0.0 0.00015 22.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 EHU02112.1 - 0.0018 17.8 0.0 0.0025 17.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EHU02112.1 - 0.0031 17.0 0.0 0.0055 16.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase ADH_N PF08240.12 EHU02112.1 - 0.024 14.5 0.0 0.078 12.9 0.0 1.8 1 1 1 2 2 2 0 Alcohol dehydrogenase GroES-like domain GDP_Man_Dehyd PF16363.5 EHU02112.1 - 0.029 13.8 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase OKR_DC_1 PF01276.20 EHU02113.1 - 1e-192 640.5 0.0 1.2e-192 640.2 0.0 1.1 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain OKR_DC_1_C PF03711.15 EHU02113.1 - 5.6e-46 156.1 0.0 1.3e-45 155.0 0.0 1.6 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, C-terminal domain OKR_DC_1_N PF03709.15 EHU02113.1 - 3e-11 43.6 0.0 5.4e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, N-terminal domain Beta_elim_lyase PF01212.21 EHU02113.1 - 0.0094 15.3 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase HTH_Tnp_1 PF01527.20 EHU02114.1 - 2.6e-15 56.5 0.0 1.6e-14 53.9 0.0 2.2 2 1 0 2 2 2 1 Transposase HTH_23 PF13384.6 EHU02114.1 - 1.4e-06 27.9 0.0 0.017 14.9 0.0 2.3 2 0 0 2 2 2 2 Homeodomain-like domain HTH_28 PF13518.6 EHU02114.1 - 0.0034 17.5 0.0 0.66 10.2 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain MarR_2 PF12802.7 EHU02114.1 - 0.054 13.4 0.1 0.68 9.9 0.0 2.3 2 0 0 2 2 2 0 MarR family LZ_Tnp_IS481 PF13011.6 EHU02114.1 - 0.084 13.4 0.2 3.4 8.3 0.0 2.6 3 0 0 3 3 3 0 leucine-zipper of insertion element IS481 TnpB_IS66 PF05717.13 EHU02115.1 - 2.7e-05 24.0 0.0 2.9e-05 23.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHU02116.1 - 2.6e-98 329.0 4.4 8.1e-98 327.4 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU02116.1 - 1.2e-16 60.6 0.0 5.2e-16 58.6 0.0 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU02116.1 - 7.2e-15 55.1 1.8 1.6e-14 54.0 1.8 1.6 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU02116.1 - 1.6e-11 44.8 9.6 3.5e-11 43.7 9.6 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHU02116.1 - 0.016 15.0 6.4 0.027 14.3 6.4 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Phage_HK97_TLTM PF06120.11 EHU02116.1 - 0.021 14.0 1.7 0.042 13.0 1.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHU02116.1 - 0.022 15.1 4.3 0.091 13.1 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Exonuc_VII_L PF02601.15 EHU02116.1 - 0.028 14.0 3.3 0.041 13.5 0.7 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit Tho2 PF11262.8 EHU02116.1 - 0.055 12.7 0.5 0.094 11.9 0.5 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Troponin PF00992.20 EHU02116.1 - 0.059 13.7 3.0 0.11 12.8 3.0 1.4 1 0 0 1 1 1 0 Troponin LXG PF04740.12 EHU02116.1 - 0.11 12.3 2.6 0.33 10.6 0.4 2.2 1 1 1 2 2 2 0 LXG domain of WXG superfamily UME PF08064.13 EHU02116.1 - 0.13 12.2 0.6 16 5.5 0.0 3.1 2 1 1 3 3 3 0 UME (NUC010) domain ERM PF00769.19 EHU02116.1 - 0.16 11.8 10.8 0.26 11.1 10.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HalX PF08663.10 EHU02116.1 - 0.21 11.9 3.1 0.59 10.5 3.1 1.8 1 0 0 1 1 1 0 HalX domain DHR10 PF18595.1 EHU02116.1 - 0.36 10.9 10.9 0.66 10.0 10.9 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF1192 PF06698.11 EHU02116.1 - 0.49 10.5 5.3 3.4 7.8 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) FUSC PF04632.12 EHU02116.1 - 0.82 8.1 12.7 0.056 12.0 6.9 1.9 2 0 0 2 2 2 0 Fusaric acid resistance protein family TMPIT PF07851.13 EHU02116.1 - 1.1 8.4 3.1 1.7 7.8 3.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein OmpH PF03938.14 EHU02116.1 - 3.1 8.1 7.9 6.7 7.0 7.9 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HAUS-augmin3 PF14932.6 EHU02116.1 - 6.5 6.3 10.0 6.1 6.3 7.9 1.9 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 Usher PF00577.20 EHU02117.1 - 6.2e-144 480.9 19.1 1.3e-143 479.8 19.1 1.5 1 1 0 1 1 1 1 Outer membrane usher protein PapC_N PF13954.6 EHU02117.1 - 4.8e-25 88.3 0.0 1e-24 87.2 0.0 1.5 1 0 0 1 1 1 1 PapC N-terminal domain PapC_C PF13953.6 EHU02117.1 - 1.3e-14 53.8 0.2 1.3e-13 50.6 0.1 2.7 2 0 0 2 2 2 1 PapC C-terminal domain fn3_3 PF14686.6 EHU02117.1 - 0.029 14.2 2.0 7.5 6.4 0.0 3.3 3 0 0 3 3 3 0 Polysaccharide lyase family 4, domain II Fimbrial PF00419.20 EHU02118.1 - 3.1e-24 86.0 0.1 6.6e-24 84.9 0.1 1.5 1 0 0 1 1 1 1 Fimbrial protein PapD_N PF00345.20 EHU02119.1 - 1.1e-25 90.0 0.0 1.7e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain PapD_C PF02753.17 EHU02119.1 - 1.3e-06 28.7 0.2 7.3e-06 26.3 0.1 2.2 2 0 0 2 2 2 1 Pili assembly chaperone PapD, C-terminal domain ADH_zinc_N_2 PF13602.6 EHU02120.1 - 8.2e-20 72.2 0.0 1.3e-19 71.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EHU02120.1 - 5e-11 42.7 0.0 7.7e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EHU02120.1 - 4.6e-08 32.9 0.0 8.7e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 EHU02120.1 - 0.037 14.3 0.0 0.085 13.1 0.0 1.7 1 1 0 1 1 1 0 TrkA-N domain YAcAr PF10686.9 EHU02120.1 - 0.4 10.7 1.7 1.7 8.7 0.3 2.8 3 1 0 3 3 3 0 YspA, cpYpsA-related SLOG family ABC_tran PF00005.27 EHU02121.1 - 1.9e-58 196.9 0.0 3.1e-31 108.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EHU02121.1 - 3.9e-16 59.7 2.4 0.00015 21.7 0.0 4.3 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 EHU02121.1 - 2.1e-13 50.1 5.1 1.9e-11 43.9 1.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EHU02121.1 - 2.5e-07 30.4 0.7 0.37 10.2 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EHU02121.1 - 7.2e-06 26.1 0.1 0.065 13.3 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EHU02121.1 - 1.5e-05 24.6 0.9 0.024 14.4 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EHU02121.1 - 2.1e-05 25.2 8.6 0.0057 17.2 0.0 3.7 4 0 0 4 4 4 2 AAA domain RsgA_GTPase PF03193.16 EHU02121.1 - 0.00013 21.9 0.1 0.035 14.0 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EHU02121.1 - 0.00075 19.8 0.3 0.47 10.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EHU02121.1 - 0.00097 19.6 6.9 0.86 10.0 3.1 3.5 2 1 0 3 3 2 2 AAA ATPase domain AAA_18 PF13238.6 EHU02121.1 - 0.0017 18.9 1.4 2.3 8.8 0.3 3.5 3 1 0 3 3 2 1 AAA domain AAA_33 PF13671.6 EHU02121.1 - 0.0019 18.3 0.0 1.3 9.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.6 EHU02121.1 - 0.002 16.9 0.1 1.7 7.2 0.1 2.8 2 1 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 EHU02121.1 - 0.002 18.3 1.1 2.8 8.2 0.0 4.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_27 PF13514.6 EHU02121.1 - 0.0023 17.5 0.4 0.41 10.2 0.0 2.7 3 0 0 3 3 2 1 AAA domain MeaB PF03308.16 EHU02121.1 - 0.0031 16.5 0.2 1.4 7.8 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 EHU02121.1 - 0.011 15.5 0.1 1.5 8.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EHU02121.1 - 0.013 15.1 0.3 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 EHU02121.1 - 0.019 15.0 0.1 1 9.4 0.0 2.7 3 0 0 3 3 2 0 Dynamin family ATP-synt_ab PF00006.25 EHU02121.1 - 0.031 13.9 0.1 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.6 EHU02121.1 - 0.034 13.9 0.2 4.3 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 EHU02121.1 - 0.038 14.2 0.8 3.5 7.9 0.0 2.8 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EHU02121.1 - 0.043 13.3 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_28 PF13521.6 EHU02121.1 - 0.068 13.4 3.2 1.2 9.3 0.0 3.1 3 1 0 3 3 2 0 AAA domain DLIC PF05783.11 EHU02121.1 - 0.076 11.8 0.1 4.9 5.9 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) NB-ARC PF00931.22 EHU02121.1 - 0.082 12.1 1.4 2 7.5 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain AAA_25 PF13481.6 EHU02121.1 - 0.099 12.2 1.9 14 5.2 0.0 3.9 4 1 0 4 4 4 0 AAA domain AAA_14 PF13173.6 EHU02121.1 - 0.1 12.6 0.0 5.7 7.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 EHU02121.1 - 0.13 12.0 0.2 6.6 6.3 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain HAUS4 PF14735.6 EHU02121.1 - 0.13 11.9 0.5 0.24 11.1 0.5 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 Jnk-SapK_ap_N PF09744.9 EHU02121.1 - 5.1 7.3 10.9 1.6 8.9 0.9 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DeoRC PF00455.22 EHU02122.1 - 8.2e-42 142.9 0.0 1.8e-41 141.8 0.0 1.5 2 0 0 2 2 2 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 EHU02122.1 - 1.6e-09 37.4 0.1 3.1e-09 36.4 0.1 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_23 PF13384.6 EHU02122.1 - 0.0023 17.7 1.1 0.0066 16.2 1.1 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Mga PF08280.11 EHU02122.1 - 0.038 14.0 0.1 0.073 13.1 0.1 1.4 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain Sigma70_r4_2 PF08281.12 EHU02122.1 - 0.065 12.9 0.1 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_11 PF08279.12 EHU02122.1 - 0.076 13.0 0.7 0.14 12.1 0.7 1.4 1 0 0 1 1 1 0 HTH domain UPF0175 PF03683.13 EHU02122.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) Pyridoxal_deC PF00282.19 EHU02123.1 - 3e-62 210.5 0.0 3.9e-62 210.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain SepSecS PF05889.13 EHU02123.1 - 1.1e-06 27.7 0.0 1.5e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Aminotran_5 PF00266.19 EHU02123.1 - 3.9e-05 22.8 0.1 0.0012 17.9 0.1 2.2 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EHU02123.1 - 9e-05 21.9 0.0 0.00016 21.1 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EHU02123.1 - 0.0016 17.7 0.0 0.0028 16.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EHU02123.1 - 0.0063 15.9 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DDE_3 PF13358.6 EHU02124.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHU02124.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHU02124.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHU02124.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHU02124.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHU02124.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHU02124.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHU02124.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 Oxidored_FMN PF00724.20 EHU02125.1 - 7.1e-86 288.6 0.0 8.9e-86 288.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 EHU02125.1 - 3.1e-20 72.6 0.0 1.9e-19 70.0 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EHU02125.1 - 7.9e-10 38.8 0.1 9.5e-09 35.4 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EHU02125.1 - 1.3e-08 34.5 0.2 0.00045 19.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EHU02125.1 - 3.9e-08 33.7 0.3 0.00022 21.7 0.1 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EHU02125.1 - 6.8e-07 29.2 5.1 4.2e-05 23.3 0.2 3.7 3 1 1 4 4 4 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EHU02125.1 - 1.2e-06 27.6 0.3 1.2e-06 27.6 0.3 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 EHU02125.1 - 4.7e-06 25.9 0.5 1.2e-05 24.6 0.5 1.7 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EHU02125.1 - 6.4e-06 25.8 1.2 1.2e-05 24.9 1.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EHU02125.1 - 0.0007 18.8 0.7 0.0013 17.9 0.7 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 EHU02125.1 - 0.0015 18.4 0.2 0.028 14.3 0.1 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MR_MLE_C PF13378.6 EHU02125.1 - 0.0019 17.8 2.8 0.0061 16.1 0.3 2.8 2 1 0 2 2 2 1 Enolase C-terminal domain-like NAD_Gly3P_dh_N PF01210.23 EHU02125.1 - 0.0037 17.3 0.2 0.12 12.3 0.0 2.9 3 0 0 3 3 3 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Amino_oxidase PF01593.24 EHU02125.1 - 0.012 15.0 0.1 0.02 14.2 0.1 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 EHU02125.1 - 0.018 14.3 0.6 0.84 8.8 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 EHU02125.1 - 0.018 14.3 0.1 0.7 9.1 0.0 2.3 2 0 0 2 2 2 0 Thi4 family GFO_IDH_MocA PF01408.22 EHU02125.1 - 0.052 14.4 0.2 66 4.4 0.0 3.9 4 0 0 4 4 4 0 Oxidoreductase family, NAD-binding Rossmann fold Lycopene_cycl PF05834.12 EHU02125.1 - 0.06 12.4 1.1 0.061 12.4 0.1 1.5 2 0 0 2 2 1 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 EHU02125.1 - 0.071 12.5 0.1 10 5.4 0.0 2.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EHU02125.1 - 0.077 12.3 0.1 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.17 EHU02125.1 - 0.078 13.6 0.7 4.7 7.9 0.2 3.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_9 PF13454.6 EHU02125.1 - 0.13 12.2 2.0 1.2 9.1 0.1 3.3 4 0 0 4 4 4 0 FAD-NAD(P)-binding ThiF PF00899.21 EHU02125.1 - 0.16 11.3 0.2 0.39 10.0 0.0 1.7 2 0 0 2 2 2 0 ThiF family K_oxygenase PF13434.6 EHU02125.1 - 0.17 11.0 0.0 8.1 5.5 0.0 2.6 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 EHU02125.1 - 0.27 9.6 0.0 0.65 8.3 0.0 1.5 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like MTS PF05175.14 EHU02126.1 - 6.2e-57 191.8 0.0 1e-56 191.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EHU02126.1 - 3.6e-08 34.0 0.0 8.2e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EHU02126.1 - 6e-07 30.1 0.0 2.9e-06 28.0 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 EHU02126.1 - 2.6e-06 27.3 0.0 8.8e-06 25.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EHU02126.1 - 0.00014 21.4 0.0 0.00027 20.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 EHU02126.1 - 0.00096 18.8 0.0 0.0022 17.7 0.0 1.5 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 EHU02126.1 - 0.0011 19.5 0.0 0.0026 18.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EHU02126.1 - 0.0039 17.0 0.0 0.012 15.4 0.0 1.8 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_18 PF12847.7 EHU02126.1 - 0.072 13.0 0.0 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 EHU02126.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF45 PF01863.17 EHU02127.1 - 9e-14 52.0 0.2 1e-13 51.8 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF45 WLM PF08325.10 EHU02127.1 - 1.3e-05 25.4 0.3 1.8e-05 24.9 0.3 1.3 1 0 0 1 1 1 1 WLM domain SprT-like PF10263.9 EHU02127.1 - 0.03 14.2 0.2 0.05 13.5 0.2 1.4 1 1 0 1 1 1 0 SprT-like family Peptidase_M56 PF05569.11 EHU02127.1 - 0.031 13.5 0.6 0.074 12.2 0.6 1.6 1 1 0 1 1 1 0 BlaR1 peptidase M56 Voltage_CLC PF00654.20 EHU02128.1 - 1.9e-67 228.0 50.8 4.2e-67 226.9 46.9 2.1 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 EHU02128.1 - 2.9e-05 24.4 0.0 0.4 11.2 0.0 2.8 2 0 0 2 2 2 2 CBS domain GFO_IDH_MocA PF01408.22 EHU02129.1 - 2.8e-24 86.2 0.1 4.1e-24 85.7 0.1 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 EHU02129.1 - 0.051 14.0 0.0 0.099 13.1 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GD_AH_C PF04295.13 EHU02130.1 - 2.2e-154 514.0 0.0 2.6e-154 513.8 0.0 1.1 1 0 0 1 1 1 1 D-galactarate dehydratase / Altronate hydrolase, C terminus SAF PF08666.12 EHU02130.1 - 1.1e-06 29.2 0.4 2.4e-06 28.0 0.4 1.7 2 0 0 2 2 2 1 SAF domain Mannitol_dh_C PF08125.13 EHU02131.1 - 1.5e-56 191.6 0.0 2.2e-56 191.1 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 EHU02131.1 - 8.6e-27 94.1 0.0 2.2e-26 92.8 0.0 1.7 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain UxaC PF02614.14 EHU02132.1 - 1.2e-222 739.8 0.1 1.4e-222 739.6 0.1 1.0 1 0 0 1 1 1 1 Glucuronate isomerase MFS_1 PF07690.16 EHU02133.1 - 5.3e-56 190.1 43.0 1.1e-47 162.7 23.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GntR PF00392.21 EHU02134.1 - 2.5e-22 78.3 0.9 5.7e-22 77.1 0.9 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family FCD PF07729.12 EHU02134.1 - 7.2e-18 65.2 8.6 1.2e-17 64.5 8.6 1.4 1 0 0 1 1 1 1 FCD domain Rrf2 PF02082.20 EHU02134.1 - 0.0023 18.2 0.1 0.0055 17.0 0.1 1.7 1 0 0 1 1 1 1 Transcriptional regulator Fe_dep_repress PF01325.19 EHU02134.1 - 0.0035 17.5 0.1 0.0066 16.6 0.1 1.5 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain 2_5_RNA_ligase2 PF13563.6 EHU02134.1 - 0.0073 16.2 2.1 0.0073 16.2 2.1 1.6 2 1 0 2 2 2 1 2'-5' RNA ligase superfamily XFP_C PF09363.10 EHU02134.1 - 0.0099 15.4 0.1 0.016 14.7 0.1 1.3 1 0 0 1 1 1 1 XFP C-terminal domain HTH_11 PF08279.12 EHU02134.1 - 0.041 13.8 0.2 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 HTH domain HTH_41 PF14502.6 EHU02134.1 - 0.055 13.2 0.1 0.1 12.3 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_46 PF15977.5 EHU02134.1 - 0.1 12.6 0.5 0.51 10.4 0.1 2.3 3 0 0 3 3 3 0 Winged helix-turn-helix DNA binding SNARE_assoc PF09335.11 EHU02135.1 - 1.7e-20 73.7 6.6 1.7e-20 73.7 6.6 1.8 2 0 0 2 2 2 1 SNARE associated Golgi protein Phage_holin_5_2 PF16079.5 EHU02135.1 - 0.66 10.4 3.4 2.8 8.4 0.1 3.3 3 2 0 4 4 4 0 Phage holin family Hol44, in holin superfamily V SecD-TM1 PF13721.6 EHU02136.1 - 9.2e-19 67.8 0.0 1.1e-18 67.5 0.0 1.0 1 0 0 1 1 1 1 SecD export protein N-terminal TM region MNSV_P7B PF06692.11 EHU02136.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Melon necrotic spot virus P7B protein DUF1090 PF06476.12 EHU02137.1 - 3.9e-34 117.1 17.6 4.6e-34 116.8 17.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1090) AKAP2_C PF15304.6 EHU02137.1 - 0.0091 15.3 5.9 0.0091 15.3 5.9 1.3 1 1 0 1 1 1 1 A-kinase anchor protein 2 C-terminus Pox_T4_C PF04490.12 EHU02137.1 - 0.031 14.5 1.5 0.039 14.1 1.5 1.2 1 0 0 1 1 1 0 Poxvirus T4 protein, C terminus PepSY_TM_like_2 PF16357.5 EHU02137.1 - 0.11 12.4 1.7 0.17 11.8 1.6 1.4 1 1 0 1 1 1 0 Putative PepSY_TM-like Acyl-thio_N PF12590.8 EHU02137.1 - 0.2 12.2 0.3 0.25 11.9 0.3 1.2 1 0 0 1 1 1 0 Acyl-ATP thioesterase O-antigen_lig PF13425.6 EHU02137.1 - 0.25 10.1 1.9 0.28 9.9 1.9 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF4407 PF14362.6 EHU02137.1 - 0.33 10.3 8.4 0.43 9.9 8.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_23 PF13476.6 EHU02137.1 - 0.55 10.7 11.8 0.67 10.4 11.8 1.1 1 0 0 1 1 1 0 AAA domain Tli4_N PF18443.1 EHU02137.1 - 0.95 9.8 8.2 0.46 10.8 4.9 2.0 1 1 1 2 2 2 0 Tle cognate immunity protein 4 N-terminal domain FapA PF03961.13 EHU02137.1 - 1 7.9 10.4 1.1 7.7 10.4 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Exonuc_VII_L PF02601.15 EHU02137.1 - 1.4 8.4 9.4 1.8 8.1 9.4 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit HSP70 PF00012.20 EHU02137.1 - 4.2 5.4 13.3 4.8 5.3 13.3 1.0 1 0 0 1 1 1 0 Hsp70 protein I_LWEQ PF01608.17 EHU02137.1 - 5.5 7.2 17.5 4.9 7.4 14.7 2.2 1 1 1 2 2 2 0 I/LWEQ domain Presenilin PF01080.17 EHU02137.1 - 7.7 5.2 5.1 8.3 5.1 5.1 1.0 1 0 0 1 1 1 0 Presenilin DUF883 PF05957.13 EHU02138.1 - 2.1e-26 92.3 1.5 2.4e-26 92.2 1.5 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 EHU02138.1 - 0.00039 20.9 7.0 0.14 12.7 0.4 2.9 2 1 0 2 2 2 2 YtxH-like protein Apolipoprotein PF01442.18 EHU02138.1 - 0.0056 16.6 3.8 0.0067 16.3 3.8 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Gly-zipper_YMGG PF13441.6 EHU02138.1 - 0.0066 16.2 0.4 0.0093 15.7 0.4 1.2 1 0 0 1 1 1 1 YMGG-like Gly-zipper DUF1640 PF07798.11 EHU02138.1 - 0.024 14.7 1.4 0.037 14.1 1.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Remorin_C PF03763.13 EHU02138.1 - 0.057 13.3 1.3 0.071 13.0 1.3 1.1 1 0 0 1 1 1 0 Remorin, C-terminal region K-box PF01486.17 EHU02138.1 - 0.082 13.1 2.5 0.43 10.8 0.2 2.0 1 1 1 2 2 2 0 K-box region RNase_E_G PF10150.9 EHU02138.1 - 0.1 12.0 0.1 0.12 11.8 0.1 1.0 1 0 0 1 1 1 0 Ribonuclease E/G family DUF4404 PF14357.6 EHU02138.1 - 0.22 12.2 2.1 0.33 11.6 2.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) Phage_holin_3_6 PF07332.11 EHU02139.1 - 9.4e-23 80.4 10.2 1.1e-22 80.2 10.2 1.0 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III Claudin_2 PF13903.6 EHU02139.1 - 0.067 12.9 2.2 0.082 12.7 2.2 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF983 PF06170.12 EHU02139.1 - 0.084 13.3 6.7 4.7 7.7 5.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF983) OATP PF03137.20 EHU02139.1 - 0.2 9.9 2.7 0.23 9.7 2.7 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF373 PF04123.13 EHU02139.1 - 0.21 11.0 4.1 0.23 10.9 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF4131 PF13567.6 EHU02139.1 - 2.4 7.8 5.8 3.9 7.1 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) YqjK PF13997.6 EHU02140.1 - 5.2e-29 100.3 4.7 6e-29 100.1 4.7 1.1 1 0 0 1 1 1 1 YqjK-like protein DoxX PF07681.12 EHU02141.1 - 3.6e-18 65.9 13.1 3.6e-18 65.9 13.1 1.5 2 0 0 2 2 2 1 DoxX DoxD PF04173.13 EHU02141.1 - 0.00059 19.8 0.6 0.00059 19.8 0.6 1.9 2 0 0 2 2 2 1 TQO small subunit DoxD SURF4 PF02077.15 EHU02141.1 - 0.0086 15.7 6.1 0.032 13.8 6.1 1.9 1 1 0 1 1 1 1 SURF4 family DoxX_2 PF13564.6 EHU02141.1 - 0.016 15.3 8.2 0.022 14.8 8.0 1.4 1 1 0 1 1 1 0 DoxX-like family YlzJ PF14035.6 EHU02141.1 - 0.13 12.5 0.0 0.35 11.1 0.0 1.6 2 0 0 2 2 2 0 YlzJ-like protein DUF1270 PF06900.11 EHU02141.1 - 0.68 10.4 6.3 16 5.9 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1270) SpoIIIAC PF06686.11 EHU02141.1 - 0.97 9.7 5.2 4.1 7.6 0.2 3.0 2 1 1 3 3 3 0 Stage III sporulation protein AC/AD protein family Ni_hydr_CYTB PF01292.20 EHU02142.1 - 1.6e-07 31.1 17.4 2e-07 30.8 17.4 1.0 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 VIT1 PF01988.19 EHU02143.1 - 1.5e-51 175.4 16.2 1.7e-51 175.2 16.2 1.0 1 0 0 1 1 1 1 VIT family SpoIIM PF01944.17 EHU02143.1 - 0.0037 17.3 8.3 0.011 15.8 5.6 2.2 2 0 0 2 2 2 1 Stage II sporulation protein M Formyl_trans_N PF00551.19 EHU02144.1 - 1.9e-24 86.4 0.0 2.6e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 EHU02144.1 - 1.1e-19 70.5 0.0 1.7e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain GST_N_2 PF13409.6 EHU02145.1 - 1.7e-23 82.6 0.0 4.9e-23 81.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EHU02145.1 - 1.4e-12 47.5 0.1 2.7e-12 46.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EHU02145.1 - 1.2e-05 25.4 0.0 1.8e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EHU02145.1 - 6.8e-05 23.2 0.0 0.0014 19.0 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EHU02145.1 - 0.00018 21.7 0.0 0.00034 20.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DDE_Tnp_IS66 PF03050.14 EHU02146.1 - 1.7e-99 332.9 2.7 1.9e-98 329.4 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU02146.1 - 3.1e-16 59.3 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU02146.1 - 1.4e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU02146.1 - 9e-12 45.6 8.5 1.9e-11 44.6 8.5 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHU02146.1 - 0.016 15.0 5.4 0.024 14.4 5.4 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Phage_HK97_TLTM PF06120.11 EHU02146.1 - 0.018 14.2 1.5 0.035 13.3 1.5 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHU02146.1 - 0.021 15.1 4.1 0.091 13.1 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain FUSC PF04632.12 EHU02146.1 - 0.032 12.8 6.9 0.055 12.0 6.9 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 EHU02146.1 - 0.046 13.3 1.8 0.064 12.8 0.6 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit LXG PF04740.12 EHU02146.1 - 0.048 13.4 2.0 0.33 10.6 0.4 2.2 1 1 1 2 2 2 0 LXG domain of WXG superfamily Tho2 PF11262.8 EHU02146.1 - 0.078 12.2 0.6 0.13 11.5 0.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 HalX PF08663.10 EHU02146.1 - 0.13 12.6 2.9 0.34 11.3 2.9 1.7 1 0 0 1 1 1 0 HalX domain ERM PF00769.19 EHU02146.1 - 0.2 11.4 11.0 0.33 10.7 11.0 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF1192 PF06698.11 EHU02146.1 - 0.33 11.0 4.9 3.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DHR10 PF18595.1 EHU02146.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Zn-ribbon_8 PF09723.10 EHU02146.1 - 0.44 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain OmpH PF03938.14 EHU02146.1 - 0.62 10.4 5.4 1.3 9.3 5.4 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HAUS-augmin3 PF14932.6 EHU02146.1 - 0.78 9.3 7.3 1.7 8.2 7.3 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 CREPT PF16566.5 EHU02146.1 - 1.3 9.2 8.0 0.58 10.3 4.9 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour ABC_tran_CTD PF16326.5 EHU02146.1 - 1.9 8.8 6.9 0.3 11.4 1.2 2.4 2 1 0 2 2 2 0 ABC transporter C-terminal domain SlyX PF04102.12 EHU02146.1 - 8.7 7.0 8.7 1.5e+03 -0.1 8.7 3.1 1 1 0 1 1 1 0 SlyX TnpB_IS66 PF05717.13 EHU02147.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHU02148.1 - 2.2e-08 34.3 0.0 3.1e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Transposase MdoG PF04349.12 EHU02149.1 - 1.2e-177 591.7 0.0 1.3e-177 591.5 0.0 1.0 1 0 0 1 1 1 1 Periplasmic glucan biosynthesis protein, MdoG TAT_signal PF10518.9 EHU02149.1 - 0.021 14.7 0.7 0.021 14.7 0.7 1.8 1 1 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence TP_methylase PF00590.20 EHU02150.1 - 2.1e-27 96.5 0.3 3.2e-27 95.9 0.2 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases LppC PF04348.13 EHU02151.1 - 3.4e-136 455.2 37.3 2.6e-91 307.1 4.6 2.0 1 1 1 2 2 2 2 LppC putative lipoprotein ANAPC3 PF12895.7 EHU02151.1 - 0.054 13.7 1.8 0.13 12.5 0.5 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EHU02151.1 - 0.093 13.3 18.1 0.4 11.2 2.9 3.5 3 1 0 4 4 4 0 Tetratricopeptide repeat UPF0102 PF02021.17 EHU02152.1 - 5.1e-25 87.5 0.1 6.2e-25 87.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0102 NERD PF08378.11 EHU02152.1 - 0.019 15.4 0.0 0.023 15.1 0.0 1.2 1 0 0 1 1 1 0 Nuclease-related domain Anemone_cytotox PF06369.12 EHU02152.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Sea anemone cytotoxic protein SIS_2 PF13580.6 EHU02153.1 - 3.3e-33 114.6 1.6 4e-33 114.4 1.6 1.1 1 0 0 1 1 1 1 SIS domain SIS PF01380.22 EHU02153.1 - 4.7e-07 29.7 0.6 3.3e-06 27.0 0.0 2.4 3 0 0 3 3 3 1 SIS domain HobA PF12163.8 EHU02153.1 - 0.023 14.2 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 DNA replication regulator BON PF04972.17 EHU02154.1 - 3.1e-33 113.9 5.1 6.1e-17 61.7 0.3 2.3 2 0 0 2 2 2 2 BON domain NIR_SIR_ferr PF03460.17 EHU02154.1 - 0.062 13.2 0.1 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 Nitrite/Sulfite reductase ferredoxin-like half domain Pirin PF02678.16 EHU02155.1 - 2e-23 82.4 0.0 4.7e-23 81.2 0.0 1.6 2 0 0 2 2 2 1 Pirin Pirin_C_2 PF17954.1 EHU02155.1 - 4.1e-21 75.0 0.2 8.9e-21 73.9 0.1 1.6 2 0 0 2 2 2 1 Quercetinase C-terminal cupin domain Cupin_2 PF07883.11 EHU02155.1 - 0.00078 19.1 0.0 0.0029 17.3 0.0 1.8 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 EHU02155.1 - 0.056 13.1 0.0 0.17 11.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF861) LysR_substrate PF03466.20 EHU02156.1 - 1.5e-17 63.7 0.9 2.4e-17 63.0 0.9 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EHU02156.1 - 2.4e-16 59.4 0.1 5.4e-16 58.3 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 EHU02156.1 - 0.012 15.5 0.1 0.026 14.4 0.1 1.6 1 0 0 1 1 1 0 MarR family DUF536 PF04394.14 EHU02156.1 - 0.044 13.6 2.2 0.075 12.9 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF536 HTH_20 PF12840.7 EHU02156.1 - 0.096 12.8 0.1 0.096 12.8 0.1 2.2 3 0 0 3 3 3 0 Helix-turn-helix domain Amidohydro_3 PF07969.11 EHU02157.1 - 2e-08 34.1 0.1 9.6e-06 25.3 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 EHU02157.1 - 7.5e-08 32.1 0.3 3.9e-06 26.4 0.0 2.6 2 1 0 2 2 2 1 Amidohydrolase family MarR_2 PF12802.7 EHU02157.1 - 6.5e-05 22.7 0.1 0.0014 18.5 0.1 2.5 2 0 0 2 2 2 1 MarR family HTH_24 PF13412.6 EHU02157.1 - 0.082 12.5 0.1 0.2 11.2 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR PF01047.22 EHU02157.1 - 0.1 12.6 0.1 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 MarR family UPF0122 PF04297.14 EHU02157.1 - 0.24 11.7 0.0 0.63 10.3 0.0 1.7 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like DUF4310 PF14187.6 EHU02158.1 - 8.9e-104 345.7 27.7 1e-103 345.5 27.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4310) DUF4311 PF14188.6 EHU02159.1 - 3.2e-122 406.2 13.0 3.9e-122 405.9 13.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4311) DUF2232 PF09991.9 EHU02159.1 - 0.047 12.9 12.2 0.023 13.9 8.0 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2232) DUF3169 PF11368.8 EHU02159.1 - 9.9 5.6 14.4 6.7 6.1 1.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) DUF4312 PF14189.6 EHU02160.1 - 1.2e-36 124.6 0.9 1.3e-36 124.4 0.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4312) RTT107_BRCT_5 PF16770.5 EHU02160.1 - 0.04 13.8 0.1 0.047 13.6 0.1 1.2 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain Gly_rich_SFCGS PF14272.6 EHU02161.1 - 7.5e-61 203.1 6.8 8.5e-61 203.0 6.8 1.0 1 0 0 1 1 1 1 Glycine-rich SFCGS DUF2620 PF10941.8 EHU02161.1 - 0.0023 18.1 3.9 0.0046 17.1 3.9 1.5 1 1 0 1 1 1 1 Protein of unknown function DUF2620 LacAB_rpiB PF02502.18 EHU02161.1 - 0.0051 16.8 0.2 0.0065 16.5 0.2 1.3 1 0 0 1 1 1 1 Ribose/Galactose Isomerase PRD PF00874.20 EHU02162.1 - 0.032 14.5 0.0 0.04 14.2 0.0 1.3 1 0 0 1 1 1 0 PRD domain MFS_2 PF13347.6 EHU02163.1 - 2.2e-81 273.6 31.9 2.5e-81 273.4 31.9 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 EHU02163.1 - 2.4e-10 39.9 57.8 9.4e-09 34.6 27.6 3.2 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 EHU02164.1 - 1.6e-79 267.5 27.8 1.8e-79 267.4 27.8 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 EHU02164.1 - 2.2e-07 30.1 45.4 0.0005 19.1 16.9 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily TauE PF01925.19 EHU02165.1 - 3.8e-29 102.0 36.1 3.8e-29 102.0 36.1 1.5 1 1 0 1 1 1 1 Sulfite exporter TauE/SafE YfmQ PF10787.9 EHU02165.1 - 0.13 12.0 0.4 0.27 11.0 0.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein from bacillus cereus group Glyco_hydro_31 PF01055.26 EHU02166.1 - 6.8e-73 246.3 4.7 9.2e-73 245.9 4.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EHU02166.1 - 1.2e-06 28.7 1.6 0.0001 22.5 0.5 3.3 2 1 0 2 2 2 1 Galactose mutarotase-like Aldose_epim PF01263.20 EHU02167.1 - 4.6e-39 134.5 0.0 1.2e-38 133.1 0.0 1.5 1 1 0 1 1 1 1 Aldose 1-epimerase GlcNAc_2-epim PF07221.11 EHU02168.1 - 7.7e-127 423.3 12.4 9.7e-127 422.9 12.4 1.0 1 0 0 1 1 1 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Glyco_hydro_76 PF03663.14 EHU02168.1 - 0.34 10.4 8.5 3.4 7.1 4.6 2.5 2 1 0 2 2 2 0 Glycosyl hydrolase family 76 Glyco_hydro_47 PF01532.20 EHU02168.1 - 0.48 9.3 2.5 0.87 8.4 0.1 2.0 2 0 0 2 2 2 0 Glycosyl hydrolase family 47 DeoC PF01791.9 EHU02169.1 - 1.6e-52 178.5 0.0 1.8e-52 178.3 0.0 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase NAD_binding_2 PF03446.15 EHU02170.1 - 3.8e-44 150.6 0.7 5.2e-44 150.2 0.7 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EHU02170.1 - 7.5e-26 90.8 0.1 1.8e-25 89.6 0.0 1.7 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 EHU02170.1 - 1e-08 35.6 0.1 3e-08 34.1 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 EHU02170.1 - 3e-05 24.0 0.1 5.2e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 EHU02170.1 - 0.00077 19.7 0.0 0.0014 18.8 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 EHU02170.1 - 0.00081 19.0 0.0 0.0072 15.9 0.0 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IlvN PF07991.12 EHU02170.1 - 0.02 14.5 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 EHU02170.1 - 0.029 13.8 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.15 EHU02170.1 - 0.093 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family ApbA PF02558.16 EHU02170.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 EHU02170.1 - 0.17 11.9 0.0 0.48 10.5 0.1 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase PfkB PF00294.24 EHU02171.1 - 9.3e-58 195.9 0.1 1.2e-57 195.6 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EHU02171.1 - 0.0012 18.3 0.1 0.0021 17.5 0.1 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DeoRC PF00455.22 EHU02172.1 - 3.4e-48 163.6 0.6 4.8e-48 163.1 0.6 1.2 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 EHU02172.1 - 2.2e-21 75.3 0.9 5.6e-21 74.0 0.9 1.7 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 EHU02172.1 - 1.5e-08 34.4 0.1 3e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 HTH domain MarR PF01047.22 EHU02172.1 - 2.5e-06 27.3 0.1 4.7e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 EHU02172.1 - 3.2e-06 27.0 0.7 0.00087 19.2 0.1 2.5 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain GntR PF00392.21 EHU02172.1 - 1.4e-05 24.6 0.1 3.2e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family MarR_2 PF12802.7 EHU02172.1 - 1.7e-05 24.6 0.1 3.7e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 EHU02172.1 - 3.4e-05 23.3 0.2 6.7e-05 22.4 0.2 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_29 PF13551.6 EHU02172.1 - 4e-05 23.5 0.0 0.00011 22.1 0.0 1.8 2 0 0 2 2 1 1 Winged helix-turn helix HTH_20 PF12840.7 EHU02172.1 - 0.0001 22.3 0.1 0.00025 21.0 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Mga PF08280.11 EHU02172.1 - 0.00095 19.2 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain DDRGK PF09756.9 EHU02172.1 - 0.0013 18.4 0.0 0.0028 17.3 0.0 1.5 2 0 0 2 2 2 1 DDRGK domain Fe_dep_repress PF01325.19 EHU02172.1 - 0.0017 18.5 0.0 0.0033 17.6 0.0 1.5 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Rrf2 PF02082.20 EHU02172.1 - 0.0017 18.7 0.6 0.0072 16.6 0.1 2.1 2 0 0 2 2 2 1 Transcriptional regulator TrmB PF01978.19 EHU02172.1 - 0.0057 16.5 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.20 EHU02172.1 - 0.0076 16.1 0.1 0.015 15.2 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family RPA_C PF08784.11 EHU02172.1 - 0.0077 16.9 1.2 0.4 11.4 0.0 2.9 2 1 1 3 3 3 1 Replication protein A C terminal Sugar-bind PF04198.13 EHU02172.1 - 0.02 14.1 0.7 0.45 9.6 0.1 2.2 2 0 0 2 2 2 0 Putative sugar-binding domain HTH_12 PF08461.10 EHU02172.1 - 0.023 14.6 0.1 0.047 13.6 0.1 1.5 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_17 PF12728.7 EHU02172.1 - 0.031 14.5 0.0 0.075 13.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain DUF1670 PF07900.11 EHU02172.1 - 0.04 13.3 0.1 0.068 12.5 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1670) CoA_trans PF01144.23 EHU02172.1 - 0.043 13.2 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 Coenzyme A transferase HTH_28 PF13518.6 EHU02172.1 - 0.06 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 EHU02172.1 - 0.089 12.6 0.2 0.17 11.7 0.2 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain TFIIE_alpha PF02002.17 EHU02172.1 - 0.09 12.6 0.1 0.21 11.4 0.0 1.6 2 0 0 2 2 1 0 TFIIE alpha subunit SgrR_N PF12793.7 EHU02172.1 - 0.094 12.9 1.4 0.41 10.9 0.0 2.5 3 1 0 3 3 3 0 Sugar transport-related sRNA regulator N-term DUF4228 PF14009.6 EHU02172.1 - 0.13 12.6 0.2 0.61 10.5 0.0 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4228) Cytochrom_B562 PF07361.11 EHU02173.1 - 9.7e-32 109.7 8.5 1.1e-31 109.4 8.5 1.1 1 0 0 1 1 1 1 Cytochrome b562 DUF4363 PF14276.6 EHU02173.1 - 0.0086 16.2 0.6 0.036 14.2 0.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4363) TPR_4 PF07721.14 EHU02173.1 - 0.037 14.7 0.6 0.16 12.6 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EHU02173.1 - 0.06 13.5 1.2 0.06 13.5 1.2 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1993 PF09351.10 EHU02173.1 - 0.11 12.7 0.6 0.15 12.1 0.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1993) PmbA_TldD PF01523.16 EHU02174.1 - 1.8e-61 208.5 1.1 3.3e-61 207.6 0.0 1.8 2 0 0 2 2 2 1 Putative modulator of DNA gyrase DUF3863 PF12979.7 EHU02174.1 - 0.093 11.6 0.1 0.15 10.9 0.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) DUF615 PF04751.14 EHU02175.1 - 7.1e-57 191.7 9.8 8.7e-57 191.4 9.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF615) RICH PF05062.12 EHU02175.1 - 0.14 12.6 2.1 0.22 11.9 0.2 2.3 1 1 1 2 2 2 0 RICH domain Radical_SAM PF04055.21 EHU02175.1 - 0.43 10.9 2.2 0.69 10.3 2.2 1.5 1 1 0 1 1 1 0 Radical SAM superfamily GvpL_GvpF PF06386.11 EHU02175.1 - 0.8 9.6 9.4 0.63 9.9 1.7 2.0 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF FBPase PF00316.20 EHU02176.1 - 9.8e-84 279.5 0.1 1.2e-83 279.2 0.1 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain MCPsignal PF00015.21 EHU02177.1 - 3.2e-52 176.8 16.5 3.2e-52 176.8 16.5 3.1 2 1 1 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain TarH PF02203.15 EHU02177.1 - 7.5e-17 61.8 4.0 7.5e-17 61.8 4.0 4.8 4 1 0 5 5 5 1 Tar ligand binding domain homologue HAMP PF00672.25 EHU02177.1 - 2.4e-11 43.9 3.8 3.1e-10 40.3 1.0 3.8 3 1 0 3 3 3 1 HAMP domain 4HB_MCP_1 PF12729.7 EHU02177.1 - 1.9e-08 34.1 2.7 1.9e-08 34.1 2.7 3.5 3 1 1 4 4 4 1 Four helix bundle sensory module for signal transduction SKA1 PF07160.12 EHU02177.1 - 0.15 11.9 0.2 0.15 11.9 0.2 3.0 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 BLOC1_2 PF10046.9 EHU02177.1 - 0.17 12.2 13.6 2.2 8.7 0.9 4.6 3 2 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sec20 PF03908.13 EHU02177.1 - 0.37 10.8 14.9 1.3 8.9 0.0 4.9 4 1 0 5 5 5 0 Sec20 Adaptin_binding PF10199.9 EHU02177.1 - 5.6 7.6 7.9 3.5 8.3 0.9 2.6 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Taxilin PF09728.9 EHU02177.1 - 6.2 5.9 14.3 0.44 9.7 1.4 2.7 3 1 0 3 3 3 0 Myosin-like coiled-coil protein CHDCT2 PF08074.11 EHU02177.1 - 8 6.6 11.0 0.51 10.5 1.2 2.9 2 1 1 3 3 3 0 CHDCT2 (NUC038) domain DDE_Tnp_1_5 PF13737.6 EHU02178.1 - 1.2e-44 151.2 0.0 3.1e-44 149.9 0.0 1.7 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 EHU02178.1 - 1.9e-24 86.5 1.0 2.3e-24 86.2 1.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain LprI PF07007.12 EHU02179.1 - 2e-15 57.3 7.0 2.7e-15 56.9 7.0 1.3 1 1 0 1 1 1 1 Lysozyme inhibitor LprI Peptidase_M49 PF03571.15 EHU02179.1 - 0.079 11.3 0.1 0.091 11.1 0.1 1.0 1 0 0 1 1 1 0 Peptidase family M49 DUF441 PF04284.13 EHU02180.1 - 8.4e-47 158.7 19.0 9.8e-47 158.5 19.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF441) DUF962 PF06127.11 EHU02180.1 - 0.71 10.0 3.0 2.5 8.2 3.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF962) Pyrophosphatase PF00719.19 EHU02181.1 - 1e-54 184.6 0.0 1.2e-54 184.5 0.0 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase InPase PF18823.1 EHU02181.1 - 0.026 14.3 0.0 0.067 12.9 0.0 1.7 2 0 0 2 2 2 0 Inorganic Pyrophosphatase GGACT PF06094.12 EHU02182.1 - 3.8e-22 79.2 0.3 4.2e-22 79.0 0.3 1.0 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like TamB PF04357.13 EHU02183.1 - 8.5e-72 242.5 17.7 7e-66 223.0 2.0 6.4 4 2 3 7 7 7 3 TamB, inner membrane protein subunit of TAM complex DUF2807 PF10988.8 EHU02183.1 - 0.0017 18.2 0.1 2.9 7.6 0.0 4.2 4 0 0 4 4 4 1 Putative auto-transporter adhesin, head GIN domain DUF748 PF05359.11 EHU02183.1 - 0.014 15.6 14.1 0.1 12.8 0.3 6.1 5 2 1 6 6 6 0 Domain of Unknown Function (DUF748) Cadherin_3 PF16184.5 EHU02183.1 - 0.045 13.8 0.3 0.15 12.1 0.1 1.9 2 0 0 2 2 2 0 Cadherin-like Bac_surface_Ag PF01103.23 EHU02184.1 - 8.8e-36 124.0 3.4 1.4e-35 123.3 3.4 1.3 1 0 0 1 1 1 1 Surface antigen POTRA_TamA_1 PF17243.2 EHU02184.1 - 8.6e-20 70.6 0.0 1.8e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 POTRA domain TamA domain 1 POTRA PF07244.15 EHU02184.1 - 1.9e-14 54.0 0.1 5.8e-08 33.2 0.0 3.4 3 0 0 3 3 3 3 Surface antigen variable number repeat DUF21 PF01595.20 EHU02185.1 - 6.3e-39 133.5 5.8 1.1e-38 132.6 5.8 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 EHU02185.1 - 5.7e-22 77.5 0.1 1.4e-21 76.3 0.1 1.7 1 0 0 1 1 1 1 Transporter associated domain CBS PF00571.28 EHU02185.1 - 0.00017 21.9 1.6 0.003 18.0 0.1 3.1 3 0 0 3 3 3 1 CBS domain DUF1107 PF06526.12 EHU02186.1 - 8.6e-31 105.6 0.5 9.6e-31 105.5 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1107) YtfJ_HI0045 PF09695.10 EHU02187.1 - 1.3e-75 252.4 2.8 1.5e-75 252.2 2.8 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (YtfJ_HI0045) Redoxin PF08534.10 EHU02187.1 - 0.012 15.4 0.2 0.032 13.9 0.1 1.7 1 1 0 1 1 1 0 Redoxin Inositol_P PF00459.25 EHU02188.1 - 1.3e-47 162.6 0.1 1.6e-47 162.3 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family 5_nucleotid_C PF02872.18 EHU02189.1 - 1.7e-20 73.8 0.0 3.5e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EHU02189.1 - 1.5e-10 41.9 0.0 2.9e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FKBP_C PF00254.28 EHU02190.1 - 9.3e-27 93.2 0.0 1.8e-26 92.3 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.18 EHU02190.1 - 6.1e-19 68.8 0.0 7.7e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase OapA PF04225.12 EHU02191.1 - 9.3e-34 115.4 0.0 1.2e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 Opacity-associated protein A LysM-like domain OapA_N PF08525.11 EHU02191.1 - 2e-09 37.1 5.0 3.8e-09 36.2 5.0 1.5 1 0 0 1 1 1 1 Opacity-associated protein A N-terminal motif DDE_Tnp_IS66 PF03050.14 EHU02192.1 - 2.3e-97 325.9 3.5 1e-96 323.7 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU02192.1 - 3.4e-16 59.2 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU02192.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU02192.1 - 1.3e-11 45.1 9.0 2.6e-11 44.1 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Exonuc_VII_L PF02601.15 EHU02192.1 - 0.042 13.4 2.1 0.052 13.1 0.7 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit FUSC PF04632.12 EHU02192.1 - 0.049 12.2 7.0 0.078 11.5 7.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Phage_HK97_TLTM PF06120.11 EHU02192.1 - 0.054 12.7 1.5 0.11 11.7 1.5 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHU02192.1 - 0.15 12.4 3.6 0.93 9.9 0.3 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain UME PF08064.13 EHU02192.1 - 0.15 12.0 0.4 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain FAM184 PF15665.5 EHU02192.1 - 0.16 11.7 5.7 0.25 11.1 5.7 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B DHR10 PF18595.1 EHU02192.1 - 0.18 11.9 10.2 0.31 11.1 10.2 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Tho2 PF11262.8 EHU02192.1 - 0.2 10.9 0.3 0.32 10.2 0.3 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 LXG PF04740.12 EHU02192.1 - 0.21 11.3 2.2 0.8 9.4 0.3 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHU02192.1 - 0.23 11.2 10.2 0.38 10.5 10.2 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HHH_8 PF14716.6 EHU02192.1 - 0.28 11.6 3.7 0.55 10.6 1.8 2.4 2 1 0 2 2 2 0 Helix-hairpin-helix domain Zn-ribbon_8 PF09723.10 EHU02192.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain TSNAXIP1_N PF15739.5 EHU02192.1 - 0.47 10.9 3.2 0.99 9.8 3.2 1.5 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus TMPIT PF07851.13 EHU02192.1 - 1 8.5 2.7 1.6 7.9 2.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHU02192.1 - 3.6 7.1 7.2 9.3 5.7 7.2 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 SlyX PF04102.12 EHU02192.1 - 8.2 7.1 8.7 12 6.6 1.6 3.0 1 1 1 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHU02193.1 - 0.0004 20.3 0.0 0.00042 20.2 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein LysR_substrate PF03466.20 EHU02194.1 - 7.7e-42 143.0 0.0 1.1e-41 142.5 0.0 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EHU02194.1 - 6.9e-09 35.5 1.6 1e-08 35.0 0.4 2.0 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family Pentapeptide_2 PF01469.18 EHU02199.1 - 0.0005 19.9 0.0 0.44 10.5 0.0 2.5 1 1 0 2 2 2 2 Pentapeptide repeats (8 copies) Sporozoite_P67 PF05642.11 EHU02199.1 - 3.8 5.5 10.1 4.4 5.3 10.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GCV_H PF01597.19 EHU02199.1 - 5.3 7.0 9.5 1.8e+03 -1.2 9.4 3.1 1 1 0 1 1 1 0 Glycine cleavage H-protein YqaJ PF09588.10 EHU02201.1 - 4.2e-16 59.4 0.0 6e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain BRE1 PF08647.11 EHU02201.1 - 0.075 13.1 2.0 0.16 12.1 2.0 1.5 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Snapin_Pallidin PF14712.6 EHU02201.1 - 0.11 13.0 0.3 0.22 12.0 0.3 1.4 1 0 0 1 1 1 0 Snapin/Pallidin RecT PF03837.14 EHU02202.1 - 5.8e-57 192.4 0.0 7.5e-57 192.0 0.0 1.1 1 0 0 1 1 1 1 RecT family DUF1024 PF06260.12 EHU02204.1 - 0.018 15.3 0.0 0.025 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1024) HALZ PF02183.18 EHU02204.1 - 0.076 13.3 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper DHR10 PF18595.1 EHU02204.1 - 0.086 12.9 0.2 0.14 12.2 0.2 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Adeno_PV PF03910.13 EHU02204.1 - 0.15 10.8 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Adenovirus minor core protein PV PGDYG PF14083.6 EHU02209.1 - 0.016 15.5 0.0 0.018 15.3 0.0 1.2 1 0 0 1 1 1 0 PGDYG protein Nudix_N_2 PF14803.6 EHU02210.1 - 0.032 14.2 0.4 0.14 12.1 0.1 2.2 2 0 0 2 2 2 0 Nudix N-terminal YodL PF14191.6 EHU02211.1 - 0.14 13.0 0.0 0.17 12.7 0.0 1.1 1 0 0 1 1 1 0 YodL-like Phage_integrase PF00589.22 EHU02212.1 - 5.2e-33 114.2 0.0 1.1e-32 113.2 0.0 1.6 2 0 0 2 2 2 1 Phage integrase family Queuosine_synth PF02547.15 EHU02213.1 - 6.4e-131 436.3 0.0 7.2e-131 436.1 0.0 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein ACP_PD PF04336.12 EHU02214.1 - 2.3e-29 101.9 3.2 3.8e-29 101.2 3.2 1.3 1 0 0 1 1 1 1 Acyl carrier protein phosphodiesterase Inositol_P PF00459.25 EHU02215.1 - 9.2e-54 182.8 0.0 1.1e-53 182.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family His_Phos_2 PF00328.22 EHU02216.1 - 3.8e-21 75.9 0.0 4.5e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.22 EHU02216.1 - 0.00087 19.0 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AA_permease PF00324.21 EHU02217.1 - 3.2e-105 352.5 54.4 3.6e-105 352.3 54.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EHU02217.1 - 3.4e-41 141.5 58.8 3.8e-41 141.3 58.8 1.0 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.13 EHU02217.1 - 1.2e-06 27.6 17.7 1.2e-06 27.6 17.7 3.2 2 2 1 3 3 3 1 Spore germination protein Gemini_mov PF01708.16 EHU02217.1 - 0.13 12.0 2.0 0.37 10.6 0.9 2.4 1 1 0 1 1 1 0 Geminivirus putative movement protein Branch_AA_trans PF05525.13 EHU02218.1 - 5.5e-154 513.2 36.0 6.3e-154 513.0 36.0 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport protein Meth_synt_2 PF01717.18 EHU02219.1 - 2.6e-16 59.8 0.0 1.5e-15 57.4 0.0 1.9 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EHU02219.1 - 0.00017 21.2 0.1 0.056 13.0 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain VbhA PF18495.1 EHU02219.1 - 0.051 13.4 0.1 0.14 12.0 0.1 1.8 1 0 0 1 1 1 0 Antitoxin VbhA SHOCT PF09851.9 EHU02219.1 - 0.11 12.3 0.9 0.25 11.1 0.9 1.7 1 0 0 1 1 1 0 Short C-terminal domain DUF4334 PF14232.6 EHU02219.1 - 0.13 12.3 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4334) PBP_like_2 PF12849.7 EHU02220.1 - 1.3e-29 103.8 0.0 2.6e-29 102.8 0.0 1.5 1 1 0 1 1 1 1 PBP superfamily domain PBP_like PF12727.7 EHU02220.1 - 1.8e-13 50.1 0.0 2.3e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 PBP superfamily domain SBP_bac_11 PF13531.6 EHU02220.1 - 2.5e-08 33.9 3.0 1.8e-07 31.2 3.0 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein LysR_substrate PF03466.20 EHU02220.1 - 6.8e-05 22.3 0.7 0.0033 16.8 0.2 2.8 2 1 0 2 2 2 1 LysR substrate binding domain HAMP_N3 PF18575.1 EHU02220.1 - 0.18 11.4 0.0 0.4 10.3 0.0 1.5 1 0 0 1 1 1 0 HAMP N-terminal domain 3 PhoR PF11808.8 EHU02221.1 - 1.1e-29 102.6 10.4 1.1e-29 102.6 10.4 2.1 2 0 0 2 2 2 1 Phosphate regulon sensor protein PhoR HATPase_c PF02518.26 EHU02221.1 - 3.2e-23 82.4 0.0 5.6e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EHU02221.1 - 2e-18 66.2 1.2 4.7e-18 65.0 0.9 1.8 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 EHU02221.1 - 5.5e-08 32.8 0.0 1.4e-07 31.5 0.0 1.8 1 1 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 EHU02221.1 - 3.5e-06 26.9 0.0 5.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EHU02221.1 - 2.3e-05 24.3 0.0 4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PAS_8 PF13188.7 EHU02221.1 - 0.00021 21.3 0.0 0.00057 19.8 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 EHU02221.1 - 0.0049 17.1 0.0 0.042 14.1 0.0 2.3 1 1 0 1 1 1 1 PAS fold DUF2955 PF11168.8 EHU02221.1 - 0.061 13.2 2.4 0.11 12.3 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2955) HR1 PF02185.16 EHU02221.1 - 0.1 12.7 0.3 0.35 11.0 0.3 1.9 1 0 0 1 1 1 0 Hr1 repeat PAS_9 PF13426.7 EHU02221.1 - 0.14 12.4 0.0 0.37 11.1 0.0 1.8 1 0 0 1 1 1 0 PAS domain DUF4391 PF14335.6 EHU02221.1 - 0.17 11.5 0.2 0.32 10.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) Response_reg PF00072.24 EHU02222.1 - 3.2e-28 98.1 0.0 4.8e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 EHU02222.1 - 4.7e-28 97.1 0.1 9.2e-28 96.1 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Peripla_BP_5 PF13433.6 EHU02222.1 - 0.11 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein domain SbcD_C PF12320.8 EHU02223.1 - 2.3e-25 88.7 1.9 4.9e-25 87.7 1.9 1.6 1 0 0 1 1 1 1 Type 5 capsule protein repressor C-terminal domain Metallophos PF00149.28 EHU02223.1 - 9.3e-14 52.4 0.0 3.1e-13 50.7 0.0 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EHU02223.1 - 5.6e-09 36.4 0.0 1e-07 32.3 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SbcCD_C PF13558.6 EHU02224.1 - 1.6e-15 57.1 14.5 5e-15 55.5 0.7 4.6 3 0 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 EHU02224.1 - 2.3e-08 34.8 53.9 2.3e-08 34.8 53.9 8.8 2 2 1 3 3 3 1 AAA domain SMC_N PF02463.19 EHU02224.1 - 1.3e-07 31.3 6.0 0.001 18.5 5.1 3.0 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EHU02224.1 - 1.2e-06 28.2 0.0 4.7e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain FadA PF09403.10 EHU02224.1 - 0.0011 19.4 7.7 0.0011 19.4 7.7 12.0 7 3 5 12 12 12 1 Adhesion protein FadA AAA_21 PF13304.6 EHU02224.1 - 0.011 15.6 0.0 0.032 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system NTPase_1 PF03266.15 EHU02224.1 - 0.016 15.1 0.1 0.083 12.8 0.0 2.3 2 0 0 2 2 2 0 NTPase MMR_HSR1 PF01926.23 EHU02224.1 - 0.12 12.5 0.7 2.1 8.4 0.0 3.6 3 0 0 3 3 3 0 50S ribosome-binding GTPase cobW PF02492.19 EHU02224.1 - 0.18 11.4 3.0 0.31 10.6 0.1 2.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 EHU02224.1 - 0.45 10.8 0.0 0.45 10.8 0.0 6.1 4 2 2 7 7 7 0 AAA domain TolA PF06519.11 EHU02225.1 - 1.3e-08 34.9 0.0 1.7e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 TolA C-terminal TonB_2 PF13103.6 EHU02225.1 - 0.025 14.8 0.0 0.032 14.5 0.0 1.1 1 0 0 1 1 1 0 TonB C terminal LPAM_1 PF08139.12 EHU02225.1 - 0.085 13.4 4.1 0.16 12.5 4.1 1.5 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site ROK PF00480.20 EHU02226.1 - 3e-84 283.0 0.0 3.3e-84 282.8 0.0 1.0 1 0 0 1 1 1 1 ROK family Glucokinase PF02685.16 EHU02226.1 - 1.2e-10 40.9 0.2 5.6e-10 38.7 0.2 1.9 1 1 1 2 2 2 1 Glucokinase Hydant_A_N PF05378.13 EHU02226.1 - 0.00036 20.3 0.1 0.00084 19.1 0.1 1.6 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region BcrAD_BadFG PF01869.20 EHU02226.1 - 0.0012 18.4 0.2 0.02 14.4 0.1 2.2 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family DEDD_Tnp_IS110 PF01548.17 EHU02226.1 - 0.12 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Transposase Acetate_kinase PF00871.17 EHU02226.1 - 0.2 10.3 0.0 0.3 9.7 0.0 1.2 1 0 0 1 1 1 0 Acetokinase family RdgC PF04381.12 EHU02227.1 - 2.8e-129 430.7 0.7 3.2e-129 430.5 0.7 1.0 1 0 0 1 1 1 1 Putative exonuclease, RdgC SRPRB PF09439.10 EHU02227.1 - 0.27 10.7 2.4 0.17 11.3 0.3 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Ppnp PF06865.11 EHU02228.1 - 2.9e-34 117.3 0.0 3.2e-34 117.2 0.0 1.0 1 0 0 1 1 1 1 Pyrimidine/purine nucleoside phosphorylase YaiA PF16362.5 EHU02229.1 - 1.1e-35 121.6 3.0 1.2e-35 121.4 3.0 1.0 1 0 0 1 1 1 1 YaiA protein SKI PF01202.22 EHU02230.1 - 1.7e-44 151.7 0.0 1.9e-44 151.6 0.0 1.0 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 EHU02230.1 - 2.3e-08 34.6 0.0 7e-08 33.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 EHU02230.1 - 0.00023 21.3 0.1 0.0014 18.8 0.1 2.0 1 1 1 2 2 2 1 Cytidylate kinase-like family AAA_16 PF13191.6 EHU02230.1 - 0.00025 21.4 1.0 0.00066 20.1 1.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EHU02230.1 - 0.00035 20.6 0.0 0.00062 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EHU02230.1 - 0.00044 20.4 0.9 0.0083 16.3 1.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EHU02230.1 - 0.0032 17.7 3.5 0.0053 17.0 1.7 2.3 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EHU02230.1 - 0.0044 17.5 0.0 0.011 16.2 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EHU02230.1 - 0.0054 16.3 1.8 0.02 14.5 0.4 2.0 1 1 1 2 2 2 1 AAA domain SMC_N PF02463.19 EHU02230.1 - 0.017 14.6 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_14 PF13173.6 EHU02230.1 - 0.023 14.7 0.0 0.047 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EHU02230.1 - 0.034 13.9 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 EHU02230.1 - 0.04 14.2 0.3 0.087 13.1 0.3 1.8 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EHU02230.1 - 0.051 13.3 1.9 4.6 6.9 0.1 2.6 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 EHU02230.1 - 0.053 13.2 0.0 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EHU02230.1 - 0.055 14.0 0.0 0.068 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EHU02230.1 - 0.059 13.8 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_21 PF13304.6 EHU02230.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 EHU02230.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain tRNA_lig_kinase PF08303.11 EHU02230.1 - 0.21 11.7 0.0 0.8 9.8 0.0 1.8 2 0 0 2 2 2 0 tRNA ligase kinase domain DUF2076 PF09849.9 EHU02231.1 - 4.8e-68 230.0 26.5 8.4e-68 229.2 26.5 1.3 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) EH_Signature PF15611.6 EHU02231.1 - 0.0042 16.6 0.8 0.0071 15.8 0.8 1.3 1 1 0 1 1 1 1 EH_Signature domain PKcGMP_CC PF16808.5 EHU02231.1 - 0.0063 16.3 0.6 0.015 15.1 0.6 1.6 1 0 0 1 1 1 1 Coiled-coil N-terminus of cGMP-dependent protein kinase Dynamitin PF04912.14 EHU02231.1 - 0.04 13.2 4.5 0.053 12.9 4.5 1.1 1 0 0 1 1 1 0 Dynamitin rRNA_proc-arch PF13234.6 EHU02231.1 - 0.047 13.6 0.4 0.066 13.1 0.4 1.2 1 0 0 1 1 1 0 rRNA-processing arch domain TauE PF01925.19 EHU02231.1 - 0.15 11.7 5.4 0.76 9.4 5.5 1.8 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE TMPIT PF07851.13 EHU02231.1 - 0.33 10.2 1.3 0.43 9.8 1.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein Phage_GPO PF05929.11 EHU02231.1 - 0.89 9.1 5.3 1.2 8.7 5.3 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4407 PF14362.6 EHU02231.1 - 0.89 8.8 6.0 1.3 8.3 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1690 PF07956.11 EHU02231.1 - 7.9 6.9 8.1 39 4.6 8.1 1.9 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) DUF188 PF02639.14 EHU02232.1 - 2.7e-50 169.4 0.0 3.1e-50 169.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized BCR, YaiI/YqxD family COG1671 P5CR_dimer PF14748.6 EHU02233.1 - 1.9e-39 134.1 2.3 1.9e-39 134.1 2.3 2.0 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EHU02233.1 - 1.8e-18 66.9 0.4 4.4e-18 65.7 0.4 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EHU02233.1 - 7.6e-06 26.0 0.1 1.9e-05 24.7 0.1 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 EHU02233.1 - 1.6e-05 25.1 1.4 2.5e-05 24.5 0.2 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.22 EHU02233.1 - 0.00015 22.6 0.1 0.0004 21.2 0.1 1.8 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF937 PF06078.11 EHU02233.1 - 0.054 14.1 0.0 0.12 13.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF937) 3HCDH_N PF02737.18 EHU02233.1 - 0.73 9.7 6.2 0.13 12.1 0.2 2.4 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 EHU02234.1 - 2e-43 148.7 0.0 2.5e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 EHU02234.1 - 1.3e-16 60.3 0.1 2.5e-16 59.4 0.1 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 EHU02234.1 - 2.8e-11 43.8 0.3 9.2e-11 42.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 EHU02234.1 - 9.6e-11 41.5 0.0 2.4e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Pyr_redox_3 PF13738.6 EHU02234.1 - 6e-08 32.3 0.0 4.6e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EHU02234.1 - 8.8e-06 25.5 0.3 0.19 11.3 0.0 3.7 2 1 1 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.22 EHU02234.1 - 1.5e-05 24.3 0.2 0.17 11.0 0.0 3.2 2 1 0 3 3 3 2 Glucose inhibited division protein A Reductase_C PF14759.6 EHU02234.1 - 6.1e-05 23.5 0.1 0.00022 21.7 0.1 2.1 2 0 0 2 2 1 1 Reductase C-terminal NAD_binding_9 PF13454.6 EHU02234.1 - 6.4e-05 23.0 0.4 1.3 9.0 0.0 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EHU02234.1 - 0.00018 21.7 0.0 0.031 14.5 0.1 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 EHU02234.1 - 0.0011 17.9 0.1 0.023 13.6 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase TrkA_N PF02254.18 EHU02234.1 - 0.0019 18.4 0.0 1.1 9.5 0.0 3.2 3 0 0 3 3 3 1 TrkA-N domain HI0933_like PF03486.14 EHU02234.1 - 0.0028 16.4 0.1 0.28 9.9 0.0 3.1 3 1 1 4 4 4 1 HI0933-like protein Lycopene_cycl PF05834.12 EHU02234.1 - 0.081 12.0 0.3 24 3.8 0.0 3.6 2 2 2 4 4 4 0 Lycopene cyclase protein K_oxygenase PF13434.6 EHU02234.1 - 0.1 11.7 0.1 0.25 10.5 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) PsiF_repeat PF07769.14 EHU02235.1 - 1.3e-32 111.3 18.9 7e-17 61.0 5.8 2.2 2 0 0 2 2 2 2 psiF repeat Salp15 PF12115.8 EHU02235.1 - 0.0062 17.0 0.4 0.0074 16.7 0.4 1.1 1 0 0 1 1 1 1 Salivary protein of 15kDa inhibits CD4+ T cell activation Anti-adapt_IraP PF10796.9 EHU02236.1 - 4.5e-21 75.2 3.6 5e-21 75.1 3.6 1.0 1 0 0 1 1 1 1 Sigma-S stabilisation anti-adaptor protein DUF4704 PF15787.5 EHU02236.1 - 0.0088 15.3 0.4 0.0092 15.2 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) TetR_C_4 PF08359.11 EHU02236.1 - 0.016 15.3 0.7 0.018 15.2 0.7 1.1 1 0 0 1 1 1 0 YsiA-like protein, C-terminal region DDE_Tnp_IS66 PF03050.14 EHU02237.1 - 2.7e-97 325.6 3.4 1.2e-96 323.5 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU02237.1 - 3.4e-16 59.1 0.1 1.3e-15 57.3 0.1 2.1 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU02237.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU02237.1 - 1.2e-11 45.2 9.0 2.6e-11 44.1 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Exonuc_VII_L PF02601.15 EHU02237.1 - 0.042 13.4 2.1 0.052 13.1 0.7 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit FUSC PF04632.12 EHU02237.1 - 0.049 12.2 7.0 0.078 11.5 7.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Phage_HK97_TLTM PF06120.11 EHU02237.1 - 0.054 12.7 1.5 0.11 11.7 1.5 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHU02237.1 - 0.15 12.4 3.6 0.93 9.9 0.3 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain UME PF08064.13 EHU02237.1 - 0.15 12.0 0.4 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain FAM184 PF15665.5 EHU02237.1 - 0.16 11.7 5.7 0.25 11.1 5.7 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B DHR10 PF18595.1 EHU02237.1 - 0.18 11.9 10.2 0.31 11.1 10.2 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Tho2 PF11262.8 EHU02237.1 - 0.2 10.9 0.3 0.32 10.2 0.3 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 LXG PF04740.12 EHU02237.1 - 0.21 11.3 2.2 0.8 9.4 0.3 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHU02237.1 - 0.23 11.2 10.2 0.38 10.5 10.2 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HHH_8 PF14716.6 EHU02237.1 - 0.28 11.6 3.7 0.55 10.6 1.8 2.4 2 1 0 2 2 2 0 Helix-hairpin-helix domain Zn-ribbon_8 PF09723.10 EHU02237.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain TSNAXIP1_N PF15739.5 EHU02237.1 - 0.47 10.9 3.2 0.99 9.8 3.2 1.5 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus TMPIT PF07851.13 EHU02237.1 - 1 8.5 2.7 1.6 7.9 2.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHU02237.1 - 3.6 7.1 7.2 9.3 5.7 7.2 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 SlyX PF04102.12 EHU02237.1 - 8.2 7.1 8.7 12 6.6 1.6 3.0 1 1 1 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHU02238.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHU02239.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU02239.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU02239.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU02239.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix MFS_1 PF07690.16 EHU02240.1 - 1.2e-58 198.7 48.6 3.2e-55 187.5 29.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EHU02240.1 - 9e-08 31.4 29.6 1e-06 27.9 9.5 2.6 2 1 1 3 3 3 2 Sugar (and other) transporter Phage_holin_3_6 PF07332.11 EHU02240.1 - 0.95 9.5 0.0 0.95 9.5 0.0 4.7 3 1 1 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III Ferritin PF00210.24 EHU02241.1 - 5.6e-39 133.3 1.4 7e-39 133.0 1.4 1.0 1 0 0 1 1 1 1 Ferritin-like domain Ferritin-like PF12902.7 EHU02241.1 - 0.0045 16.9 0.1 0.0062 16.4 0.1 1.4 1 1 0 1 1 1 1 Ferritin-like Pentapeptide PF00805.22 EHU02242.1 - 5.3e-27 93.1 4.8 7.4e-09 35.1 0.0 4.5 2 2 2 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 EHU02242.1 - 1.5e-24 85.9 14.9 3.4e-12 46.4 6.8 3.2 2 1 1 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 EHU02242.1 - 2e-11 43.8 20.3 0.00028 21.0 0.0 4.7 2 1 3 5 5 5 3 Pentapeptide repeats (9 copies) RF3_C PF16658.5 EHU02243.1 - 9.1e-47 158.2 0.0 1.6e-46 157.4 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU PF00009.27 EHU02243.1 - 2.3e-45 154.5 0.0 3.6e-45 153.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EHU02243.1 - 7.9e-12 45.4 0.1 2.6e-11 43.7 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EHU02243.1 - 5e-05 23.3 0.0 0.0001 22.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 EHU02243.1 - 0.00037 20.5 0.0 0.0007 19.6 0.0 1.4 1 0 0 1 1 1 1 Elongation Factor G, domain II Phg_2220_C PF09524.10 EHU02243.1 - 0.083 13.0 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Conserved phage C-terminus (Phg_2220_C) BON PF04972.17 EHU02244.1 - 1.7e-40 137.2 22.2 5.4e-20 71.5 6.6 3.1 3 0 0 3 3 3 2 BON domain DUF1471 PF07338.13 EHU02244.1 - 0.0059 16.6 2.9 1.7 8.7 0.5 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF1471) DUF1328 PF07043.13 EHU02245.1 - 1.5e-13 50.7 22.5 1.8e-13 50.5 22.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1328) ThrE PF06738.12 EHU02245.1 - 0.15 11.4 7.0 0.16 11.3 7.0 1.0 1 0 0 1 1 1 0 Putative threonine/serine exporter Pox_A14 PF05767.12 EHU02245.1 - 0.21 11.7 4.8 0.25 11.5 4.8 1.1 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Phage_holin_3_6 PF07332.11 EHU02245.1 - 0.51 10.4 13.2 0.55 10.3 13.2 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III MttA_Hcf106 PF02416.16 EHU02245.1 - 0.92 8.9 5.7 1.9 7.9 0.6 2.2 2 0 0 2 2 2 0 mttA/Hcf106 family DUF2721 PF11026.8 EHU02245.1 - 1.3 9.0 8.1 1.4 8.8 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF4389 PF14333.6 EHU02245.1 - 2.7 8.0 6.9 18 5.3 6.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4389) DUF1676 PF07898.13 EHU02245.1 - 7.3 6.6 7.2 8.1 6.5 7.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) DDE_3 PF13358.6 EHU02246.1 - 4.7e-20 71.8 0.1 5.4e-20 71.6 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_1 PF01527.20 EHU02247.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU02247.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU02247.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU02247.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHU02248.1 - 7.4e-39 131.7 0.0 8.3e-39 131.6 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHU02249.1 - 2.8e-99 332.1 3.5 1.6e-98 329.7 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU02249.1 - 3.1e-16 59.3 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU02249.1 - 8e-15 55.0 1.3 1.9e-14 53.8 1.3 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU02249.1 - 1.7e-11 44.7 9.6 3.5e-11 43.7 9.6 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain FAM184 PF15665.5 EHU02249.1 - 0.017 14.9 6.4 0.027 14.3 6.4 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Phage_HK97_TLTM PF06120.11 EHU02249.1 - 0.021 14.0 1.7 0.042 13.0 1.7 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHU02249.1 - 0.022 15.1 4.3 0.091 13.1 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Exonuc_VII_L PF02601.15 EHU02249.1 - 0.028 14.0 1.8 0.039 13.5 0.6 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit FUSC PF04632.12 EHU02249.1 - 0.03 12.9 6.9 0.056 12.0 6.9 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tho2 PF11262.8 EHU02249.1 - 0.057 12.6 0.5 0.094 11.9 0.5 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Troponin PF00992.20 EHU02249.1 - 0.062 13.6 3.0 0.11 12.8 3.0 1.3 1 0 0 1 1 1 0 Troponin LXG PF04740.12 EHU02249.1 - 0.11 12.2 2.6 0.33 10.6 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHU02249.1 - 0.16 11.8 10.8 0.26 11.1 10.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family UME PF08064.13 EHU02249.1 - 0.16 11.9 0.5 21 5.1 0.0 3.0 2 1 1 3 3 3 0 UME (NUC010) domain HalX PF08663.10 EHU02249.1 - 0.23 11.8 3.1 0.59 10.5 3.1 1.7 1 0 0 1 1 1 0 HalX domain DHR10 PF18595.1 EHU02249.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF1192 PF06698.11 EHU02249.1 - 0.47 10.5 5.3 3.4 7.8 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHU02249.1 - 1.1 8.4 3.1 1.7 7.8 3.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHU02249.1 - 2.8 7.4 7.9 6.1 6.3 7.9 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHU02249.1 - 3.2 8.1 7.9 6.7 7.0 7.9 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 EHU02249.1 - 7.1 7.3 8.7 7.7 7.2 1.0 3.1 1 1 1 2 2 2 0 SlyX IucA_IucC PF04183.12 EHU02250.1 - 1.4e-80 270.4 0.1 2.6e-80 269.4 0.1 1.5 1 0 0 1 1 1 1 IucA / IucC family Acetyltransf_8 PF13523.6 EHU02250.1 - 5.4e-52 175.3 0.6 1.2e-51 174.2 0.6 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FhuF PF06276.12 EHU02250.1 - 3.7e-44 151.0 1.2 8.1e-44 149.9 1.2 1.6 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter Acetyltransf_3 PF13302.7 EHU02250.1 - 3.5e-06 27.7 0.1 1e-05 26.3 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain RVT_1 PF00078.27 EHU02251.1 - 8.7e-43 146.4 0.0 1.7e-42 145.4 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) GIIM PF08388.11 EHU02251.1 - 1.2e-17 63.7 4.0 3e-17 62.4 4.0 1.7 1 0 0 1 1 1 1 Group II intron, maturase-specific domain MFS_1 PF07690.16 EHU02252.1 - 1.3e-30 106.5 77.9 4.7e-29 101.4 47.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EHU02252.1 - 8.3e-05 21.6 8.0 8.3e-05 21.6 8.0 3.1 2 1 0 2 2 2 1 Sugar (and other) transporter DUF5325 PF17259.2 EHU02252.1 - 0.3 11.0 0.1 0.3 11.0 0.1 3.6 3 0 0 3 3 3 0 Family of unknown function (DUF5325) ABC_tran PF00005.27 EHU02253.1 - 7.2e-32 110.8 0.0 9.3e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EHU02253.1 - 3.3e-12 46.9 0.0 6.3e-07 29.5 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EHU02253.1 - 0.00016 21.6 0.1 0.00049 20.0 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 EHU02253.1 - 0.00058 20.4 0.0 0.00088 19.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EHU02253.1 - 0.0014 18.4 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EHU02253.1 - 0.0034 17.8 0.0 0.0044 17.4 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 EHU02253.1 - 0.0062 16.3 0.0 0.0081 15.9 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EHU02253.1 - 0.018 15.0 0.2 0.04 13.8 0.2 1.6 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 EHU02253.1 - 0.049 13.9 1.0 0.24 11.7 1.0 2.0 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EHU02253.1 - 0.06 12.7 0.2 0.36 10.2 0.1 1.9 1 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 EHU02253.1 - 0.063 13.0 0.0 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EHU02253.1 - 0.097 12.4 0.2 0.86 9.3 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein SMC_N PF02463.19 EHU02253.1 - 0.17 11.3 0.0 0.27 10.7 0.0 1.6 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain DUF3584 PF12128.8 EHU02253.1 - 0.19 9.2 0.2 0.25 8.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ABC_tran PF00005.27 EHU02254.1 - 7.7e-30 104.2 0.0 1.2e-29 103.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EHU02254.1 - 2.4e-09 37.4 0.4 4.4e-05 23.4 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system BCA_ABC_TP_C PF12399.8 EHU02254.1 - 2.6e-07 30.4 0.1 4.5e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter SMC_N PF02463.19 EHU02254.1 - 6.3e-07 29.0 0.0 2.8e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EHU02254.1 - 1.3e-06 29.0 0.7 2.9e-06 27.9 0.2 1.6 1 1 1 2 2 2 1 AAA domain AAA_15 PF13175.6 EHU02254.1 - 6.3e-05 22.8 0.0 0.0001 22.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EHU02254.1 - 0.00057 19.6 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EHU02254.1 - 0.00066 20.0 0.7 0.02 15.1 0.7 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EHU02254.1 - 0.0015 18.3 0.0 0.0032 17.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EHU02254.1 - 0.0067 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EHU02254.1 - 0.014 15.8 0.1 0.022 15.1 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain ATP-synt_ab PF00006.25 EHU02254.1 - 0.018 14.7 0.0 0.087 12.5 0.0 1.9 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_27 PF13514.6 EHU02254.1 - 0.02 14.5 0.0 0.1 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EHU02254.1 - 0.04 13.8 0.0 0.055 13.4 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF2813 PF11398.8 EHU02254.1 - 0.052 12.8 0.0 0.078 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) AAA_33 PF13671.6 EHU02254.1 - 0.057 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EHU02254.1 - 0.1 13.0 0.1 0.33 11.4 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GTP_EFTU PF00009.27 EHU02254.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_13 PF13166.6 EHU02254.1 - 0.22 10.1 0.0 0.27 9.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain BPD_transp_2 PF02653.16 EHU02255.1 - 3.9e-41 141.0 33.3 3.9e-41 141.0 33.3 1.7 1 1 0 2 2 2 1 Branched-chain amino acid transport system / permease component FxsA PF04186.13 EHU02255.1 - 0.027 14.6 0.4 0.027 14.6 0.4 3.2 3 0 0 3 3 3 0 FxsA cytoplasmic membrane protein BPD_transp_2 PF02653.16 EHU02256.1 - 6.3e-55 186.2 37.0 9.4e-55 185.6 37.0 1.3 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component HEAT_2 PF13646.6 EHU02256.1 - 1.7e-08 34.7 6.9 2.6e-05 24.5 0.4 2.7 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.22 EHU02256.1 - 0.00086 19.4 2.3 5.3 7.6 0.0 4.6 4 0 0 4 4 4 2 HEAT repeat Peripla_BP_5 PF13433.6 EHU02257.1 - 4.2e-174 578.7 0.1 4.8e-174 578.5 0.1 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_6 PF13458.6 EHU02257.1 - 8.9e-73 245.9 2.2 1.1e-72 245.6 2.2 1.0 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 EHU02257.1 - 0.0015 17.7 0.0 0.015 14.4 0.0 2.0 2 0 0 2 2 2 1 Receptor family ligand binding region Pex14_N PF04695.13 EHU02257.1 - 0.13 12.9 0.0 0.3 11.7 0.0 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FCD PF07729.12 EHU02258.1 - 1.2e-20 74.2 10.8 2e-20 73.5 10.8 1.4 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 EHU02258.1 - 1.3e-17 63.2 0.0 3.7e-17 61.7 0.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 EHU02258.1 - 0.00016 21.2 0.0 0.0025 17.4 0.0 2.5 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Fe_dep_repress PF01325.19 EHU02258.1 - 0.00047 20.3 0.0 0.0016 18.6 0.0 1.9 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_20 PF12840.7 EHU02258.1 - 0.003 17.6 0.0 0.73 9.9 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain DUF3116 PF11313.8 EHU02258.1 - 0.025 14.4 0.0 0.073 12.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3116) HTH_Crp_2 PF13545.6 EHU02258.1 - 0.026 14.5 0.0 0.074 13.0 0.0 1.9 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Rrf2 PF02082.20 EHU02258.1 - 0.027 14.8 0.0 0.16 12.4 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator HTH_11 PF08279.12 EHU02258.1 - 0.042 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 HTH domain TrmB PF01978.19 EHU02258.1 - 0.097 12.6 0.0 0.43 10.5 0.0 2.1 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB FaeA PF04703.12 EHU02258.1 - 0.13 12.6 0.0 0.32 11.4 0.0 1.7 1 0 0 1 1 1 0 FaeA-like protein CT_A_B PF02626.15 EHU02259.1 - 1.2e-94 316.9 0.0 4e-94 315.1 0.0 1.9 2 0 0 2 2 2 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 EHU02259.1 - 2.8e-60 203.4 0.0 4.9e-60 202.6 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CT_C_D PF02682.16 EHU02259.1 - 5.7e-45 153.6 0.0 2.1e-44 151.7 0.0 2.0 2 0 0 2 2 2 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_N PF00289.22 EHU02259.1 - 2.5e-42 143.9 0.8 5.6e-42 142.8 0.1 2.0 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EHU02259.1 - 2.8e-37 127.1 0.0 6.4e-37 126.0 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EHU02259.1 - 1.4e-16 60.1 0.0 6.2e-16 58.0 0.0 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EHU02259.1 - 2e-08 34.0 0.0 4e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 EHU02259.1 - 3.4e-08 33.2 0.0 0.0017 18.2 0.1 2.9 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 EHU02259.1 - 0.00023 21.8 0.1 2.7 8.8 0.0 3.6 3 0 0 3 3 3 2 HlyD family secretion protein HlyD_D23 PF16576.5 EHU02259.1 - 0.0013 18.0 0.2 0.19 10.9 0.4 2.4 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion NQRA PF05896.11 EHU02259.1 - 0.0042 16.5 0.0 0.0081 15.6 0.0 1.4 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) ATP-grasp PF02222.22 EHU02259.1 - 0.0053 16.3 0.0 0.016 14.8 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain RnfC_N PF13375.6 EHU02259.1 - 0.0066 16.4 0.2 0.023 14.7 0.1 1.9 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain ATP-grasp_5 PF13549.6 EHU02259.1 - 0.013 14.9 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Amidase PF01425.21 EHU02260.1 - 3.1e-85 286.8 0.1 5.1e-85 286.1 0.1 1.3 1 0 0 1 1 1 1 Amidase SLT PF01464.20 EHU02261.1 - 2.4e-33 114.3 0.4 4.3e-33 113.4 0.4 1.4 1 0 0 1 1 1 1 Transglycosylase SLT domain SLT_L PF14718.6 EHU02261.1 - 1.2e-22 79.8 4.6 1.2e-22 79.8 4.6 3.4 3 0 0 3 3 3 1 Soluble lytic murein transglycosylase L domain Cucumo_coat PF00760.18 EHU02261.1 - 2.7e-05 23.9 0.2 8e-05 22.4 0.1 1.8 2 0 0 2 2 2 1 Cucumovirus coat protein TPR_6 PF13174.6 EHU02261.1 - 0.065 13.9 0.7 1.3 9.8 0.2 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Trp_repressor PF01371.19 EHU02262.1 - 3e-28 97.8 0.0 3.6e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Trp repressor protein HTH_5 PF01022.20 EHU02262.1 - 0.017 15.0 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family MqsA_antitoxin PF15731.5 EHU02262.1 - 0.18 11.9 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA NTPase_I-T PF01931.18 EHU02263.1 - 2.4e-53 180.3 0.1 2.7e-53 180.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 His_Phos_1 PF00300.22 EHU02264.1 - 1.7e-56 191.0 1.6 1.9e-56 190.8 1.6 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HTH_18 PF12833.7 EHU02265.1 - 8.6e-21 74.0 1.4 7.3e-20 71.0 0.9 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain GyrI-like PF06445.15 EHU02265.1 - 1.2e-17 64.6 0.0 1.6e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 GyrI-like small molecule binding domain HTH_AraC PF00165.23 EHU02265.1 - 8.4e-15 54.4 0.3 1.1e-08 34.9 0.2 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Cass2 PF14526.6 EHU02265.1 - 1.2e-06 28.7 0.0 1.8e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Integron-associated effector binding protein GDI PF00996.18 EHU02265.1 - 0.17 10.4 0.0 0.25 9.8 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor DDE_Tnp_IS66 PF03050.14 EHU02266.1 - 2.8e-97 325.6 4.1 1.2e-96 323.5 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU02266.1 - 3.3e-16 59.2 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU02266.1 - 5.1e-15 55.6 1.4 1.2e-14 54.4 1.4 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU02266.1 - 8.8e-11 42.4 9.0 1.9e-10 41.4 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Phage_HK97_TLTM PF06120.11 EHU02266.1 - 0.015 14.5 1.2 0.029 13.6 1.2 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHU02266.1 - 0.02 15.2 4.2 0.084 13.2 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Exonuc_VII_L PF02601.15 EHU02266.1 - 0.028 14.0 2.0 0.035 13.7 0.6 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit UME PF08064.13 EHU02266.1 - 0.037 13.9 0.4 21 5.1 0.0 3.1 2 1 1 3 3 3 0 UME (NUC010) domain Troponin PF00992.20 EHU02266.1 - 0.044 14.1 2.8 0.078 13.3 2.8 1.3 1 0 0 1 1 1 0 Troponin Tho2 PF11262.8 EHU02266.1 - 0.049 12.8 0.6 0.081 12.1 0.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FUSC PF04632.12 EHU02266.1 - 0.05 12.2 7.5 0.079 11.5 7.5 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family FAM184 PF15665.5 EHU02266.1 - 0.052 13.3 8.0 0.082 12.7 8.0 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B HalX PF08663.10 EHU02266.1 - 0.13 12.6 2.4 0.34 11.3 2.4 1.7 1 0 0 1 1 1 0 HalX domain LXG PF04740.12 EHU02266.1 - 0.14 11.8 2.8 0.35 10.5 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHU02266.1 - 0.19 11.5 11.1 0.31 10.8 11.1 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DHR10 PF18595.1 EHU02266.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF1192 PF06698.11 EHU02266.1 - 0.48 10.5 5.3 3.4 7.8 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHU02266.1 - 0.82 8.9 3.0 1.2 8.3 3.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHU02266.1 - 2 7.9 8.1 4.3 6.8 8.1 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHU02266.1 - 4.2 7.7 8.6 8.7 6.7 8.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CREPT PF16566.5 EHU02266.1 - 5.9 7.0 8.7 2.7 8.1 5.6 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour SlyX PF04102.12 EHU02266.1 - 9.9 6.9 9.0 18 6.1 2.3 3.0 1 1 1 2 2 2 0 SlyX TnpB_IS66 PF05717.13 EHU02267.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein HTH_Tnp_1 PF01527.20 EHU02268.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU02268.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU02268.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU02268.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix CreA PF05981.12 EHU02269.1 - 2.4e-57 192.5 0.0 2.8e-57 192.3 0.0 1.0 1 0 0 1 1 1 1 CreA protein Response_reg PF00072.24 EHU02270.1 - 5.5e-27 94.2 0.4 1.7e-26 92.6 0.1 1.8 2 0 0 2 2 2 1 Response regulator receiver domain Trans_reg_C PF00486.28 EHU02270.1 - 2.9e-18 65.7 0.0 5.3e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal SpoU_methylase PF00588.19 EHU02271.1 - 1.2e-34 119.5 0.0 1.7e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family Methyltrn_RNA_4 PF09936.9 EHU02271.1 - 0.009 15.9 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 SAM-dependent RNA methyltransferase Homoserine_dh PF00742.19 EHU02272.1 - 5.8e-49 166.3 0.0 3.6e-48 163.7 0.0 2.3 2 0 0 2 2 2 1 Homoserine dehydrogenase AA_kinase PF00696.28 EHU02272.1 - 6.3e-46 156.9 0.3 2.5e-45 155.0 0.0 2.1 2 0 0 2 2 2 1 Amino acid kinase family NAD_binding_3 PF03447.16 EHU02272.1 - 6e-29 101.1 0.0 1.8e-28 99.6 0.0 1.9 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ACT_7 PF13840.6 EHU02272.1 - 2.5e-19 68.8 2.6 7.5e-10 38.5 0.5 3.1 3 0 0 3 3 3 2 ACT domain ACT PF01842.25 EHU02272.1 - 6.1e-18 64.3 0.5 6.5e-08 32.2 0.0 3.0 2 0 0 2 2 2 2 ACT domain GHMP_kinases_N PF00288.26 EHU02273.1 - 4.1e-15 55.8 0.2 1e-14 54.5 0.2 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EHU02273.1 - 1.3e-08 35.1 2.0 1.7e-08 34.7 0.0 2.3 2 0 0 2 2 2 1 GHMP kinases C terminal PALP PF00291.25 EHU02274.1 - 8.2e-21 74.7 0.0 1.1e-20 74.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_synth_N PF14821.6 EHU02274.1 - 1.6e-11 44.2 0.0 8e-11 42.0 0.0 2.2 2 0 0 2 2 2 1 Threonine synthase N terminus H2O2_YaaD PF03883.14 EHU02275.1 - 1.1e-92 309.8 0.1 1.2e-92 309.7 0.1 1.0 1 0 0 1 1 1 1 Peroxide stress protein YaaA TAL_FSA PF00923.19 EHU02276.1 - 1.2e-103 346.4 0.0 1.4e-103 346.2 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase MoCF_biosynth PF00994.24 EHU02277.1 - 3.3e-29 101.4 0.0 4.3e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Probable molybdopterin binding domain MFS_1 PF07690.16 EHU02278.1 - 2.1e-25 89.4 70.3 3e-23 82.3 44.0 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EHU02278.1 - 4.3e-21 75.3 29.0 4.6e-18 65.3 7.0 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 EHU02278.1 - 0.0088 14.6 19.7 0.044 12.3 16.9 2.4 1 1 1 2 2 2 2 MFS/sugar transport protein DUF4381 PF14316.6 EHU02278.1 - 0.66 10.2 10.4 0.082 13.1 0.9 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4381) 7tm_1 PF00001.21 EHU02278.1 - 6 6.1 7.5 0.54 9.5 1.4 2.1 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) CPP1-like PF11833.8 EHU02278.1 - 7.7 6.1 14.1 2.3 7.9 0.1 3.1 4 0 0 4 4 4 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like HSP70 PF00012.20 EHU02280.1 - 3.1e-267 887.6 14.9 3.6e-267 887.4 14.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EHU02280.1 - 1.8e-14 53.3 1.9 7.7e-12 44.7 0.4 2.5 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 EHU02280.1 - 1.1 9.7 11.0 8.9 6.8 0.9 3.9 3 2 0 3 3 3 0 Cell division protein FtsA DnaJ_C PF01556.18 EHU02281.1 - 3.9e-45 153.6 0.0 5e-45 153.2 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EHU02281.1 - 2.4e-27 94.8 4.7 4.2e-27 94.1 4.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EHU02281.1 - 5.6e-15 55.5 17.6 9.5e-15 54.7 17.6 1.4 1 0 0 1 1 1 1 DnaJ central domain Cytochrome_C7 PF14522.6 EHU02281.1 - 3.4e-06 27.0 6.6 0.0011 18.9 0.2 2.5 2 0 0 2 2 2 2 Cytochrome c7 and related cytochrome c Anti-TRAP PF15777.5 EHU02281.1 - 0.00023 21.0 13.5 0.0045 16.9 2.0 3.2 1 1 3 4 4 4 4 Tryptophan RNA-binding attenuator protein inhibitory protein Cytochrom_c3_2 PF14537.6 EHU02281.1 - 0.26 11.8 14.0 5.5 7.5 14.1 2.7 1 1 1 2 2 2 0 Cytochrome c3 Cytochrome_CBB3 PF13442.6 EHU02281.1 - 0.3 11.4 23.6 2.3 8.6 0.2 4.6 1 1 3 4 4 4 0 Cytochrome C oxidase, cbb3-type, subunit III zinc-ribbons_6 PF07191.12 EHU02281.1 - 5.2 7.1 8.1 11 6.1 8.1 1.5 1 0 0 1 1 1 0 zinc-ribbons Na_H_antiport_1 PF06965.12 EHU02282.1 - 3.8e-148 493.3 27.7 4.3e-148 493.2 27.7 1.0 1 0 0 1 1 1 1 Na+/H+ antiporter 1 Ribosomal_S20p PF01649.18 EHU02283.1 - 5e-27 94.4 15.0 5.5e-27 94.2 15.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S20 ToxN_toxin PF13958.6 EHU02283.1 - 0.013 15.8 0.6 0.014 15.6 0.6 1.1 1 0 0 1 1 1 0 Toxin ToxN, type III toxin-antitoxin system UPF0253 PF06786.12 EHU02283.1 - 0.04 14.2 0.4 0.066 13.5 0.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0253) FAD_syn PF06574.12 EHU02284.1 - 5.8e-57 192.0 0.0 7.7e-57 191.6 0.0 1.2 1 0 0 1 1 1 1 FAD synthetase Flavokinase PF01687.17 EHU02284.1 - 1.2e-39 135.1 0.0 1.9e-39 134.4 0.0 1.3 1 0 0 1 1 1 1 Riboflavin kinase CTP_transf_like PF01467.26 EHU02284.1 - 0.0014 18.8 0.0 0.0032 17.7 0.0 1.7 1 1 0 1 1 1 1 Cytidylyltransferase-like tRNA-synt_1 PF00133.22 EHU02285.1 - 6.9e-225 747.9 0.0 8.2e-225 747.6 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EHU02285.1 - 3e-28 98.7 0.0 5.2e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EHU02285.1 - 1.5e-19 70.1 0.2 5.5e-10 38.6 0.0 3.4 3 0 0 3 3 3 3 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.14 EHU02285.1 - 1.1e-10 41.2 4.7 1.1e-10 41.2 4.7 3.0 3 0 0 3 3 3 1 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.19 EHU02285.1 - 6.1e-08 32.4 0.0 1.1e-05 25.0 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 EHU02285.1 - 1e-05 24.6 0.0 0.0001 21.4 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (K) tRNA-synt_1_2 PF13603.6 EHU02285.1 - 0.0041 16.7 0.0 0.0085 15.6 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 DZR PF12773.7 EHU02285.1 - 0.059 13.4 2.9 0.094 12.8 1.1 2.1 2 0 0 2 2 2 0 Double zinc ribbon Peptidase_A8 PF01252.18 EHU02286.1 - 6.5e-37 126.9 11.3 7.4e-37 126.7 11.3 1.0 1 0 0 1 1 1 1 Signal peptidase (SPase) II DUF1772 PF08592.11 EHU02286.1 - 0.13 12.5 4.0 0.075 13.4 2.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) YhhN PF07947.14 EHU02286.1 - 0.39 10.3 8.7 0.11 12.1 5.7 1.6 1 1 1 2 2 2 0 YhhN family ThrE PF06738.12 EHU02286.1 - 0.58 9.5 6.1 1.3 8.3 6.1 1.6 1 1 0 1 1 1 0 Putative threonine/serine exporter FKBP_C PF00254.28 EHU02287.1 - 2e-13 50.5 0.0 3.2e-13 49.8 0.0 1.4 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ProQ_C PF17516.2 EHU02287.1 - 0.04 13.4 0.0 0.077 12.4 0.0 1.4 1 0 0 1 1 1 0 ProQ C-terminal domain LYTB PF02401.18 EHU02288.1 - 1.2e-91 306.6 0.0 1.4e-91 306.4 0.0 1.0 1 0 0 1 1 1 1 LytB protein ETF_alpha PF00766.19 EHU02288.1 - 0.027 14.5 0.1 0.069 13.2 0.1 1.6 1 0 0 1 1 1 0 Electron transfer flavoprotein FAD-binding domain ELFV_dehydrog_N PF02812.18 EHU02288.1 - 0.047 13.6 0.0 0.076 12.9 0.0 1.5 1 1 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain TPP_enzyme_M PF00205.22 EHU02288.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain DapB_C PF05173.14 EHU02289.1 - 1.5e-44 150.9 1.2 2e-44 150.5 1.2 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus DapB_N PF01113.20 EHU02289.1 - 1.2e-41 141.7 0.0 2.7e-41 140.6 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 EHU02289.1 - 0.0083 16.4 0.2 0.022 15.0 0.1 1.9 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 EHU02289.1 - 0.022 14.6 1.1 0.033 14.1 0.8 1.5 1 1 0 1 1 1 0 NAD(P)H-binding Semialdhyde_dh PF01118.24 EHU02289.1 - 0.026 15.0 0.3 0.088 13.3 0.1 2.1 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_N PF00044.24 EHU02289.1 - 0.49 10.8 2.0 2.8 8.3 0.3 2.5 3 0 0 3 3 3 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain CPSase_sm_chain PF00988.22 EHU02290.1 - 4.4e-53 178.5 0.0 7e-53 177.8 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 EHU02290.1 - 5.1e-49 166.6 0.0 8.2e-49 166.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EHU02290.1 - 1.1e-07 31.9 0.2 9.4e-06 25.5 0.1 2.4 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 EHU02290.1 - 0.071 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family CPSase_L_D2 PF02786.17 EHU02291.1 - 4.6e-116 385.7 1.0 4.8e-76 254.9 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 EHU02291.1 - 2.1e-40 137.9 0.0 5.1e-40 136.6 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain MGS PF02142.22 EHU02291.1 - 3.4e-19 68.8 0.1 1.9e-18 66.5 0.0 2.4 2 0 0 2 2 2 1 MGS-like domain ATP-grasp PF02222.22 EHU02291.1 - 3.3e-14 52.8 0.1 7.2e-07 28.9 0.1 2.3 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.14 EHU02291.1 - 1e-11 45.1 0.3 3.3e-08 33.8 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 EHU02291.1 - 4.7e-11 42.5 0.1 5.1e-07 29.5 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.13 EHU02291.1 - 3e-10 40.0 0.1 3.5e-05 23.4 0.1 2.3 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.6 EHU02291.1 - 1.2e-09 38.0 0.2 9.8e-05 22.0 0.0 4.3 4 2 0 4 4 4 2 ATP-grasp domain CoA_binding_2 PF13380.6 EHU02291.1 - 0.001 19.6 0.1 3.8 8.1 0.0 4.0 2 1 1 3 3 3 2 CoA binding domain ATP-grasp_5 PF13549.6 EHU02291.1 - 0.0032 17.0 0.0 5.1 6.5 0.0 3.4 3 0 0 3 3 3 1 ATP-grasp domain SmpA_OmlA PF04355.13 EHU02291.1 - 0.029 14.2 0.0 0.066 13.0 0.0 1.5 1 0 0 1 1 1 0 SmpA / OmlA family Isochorismatase PF00857.20 EHU02291.1 - 0.14 12.4 0.2 1.4 9.0 0.1 2.5 2 0 0 2 2 2 0 Isochorismatase family Autotransporter PF03797.19 EHU02292.1 - 7.6e-06 25.8 11.7 7.6e-06 25.8 11.7 1.9 1 1 0 1 1 1 1 Autotransporter beta-domain DHFR_1 PF00186.19 EHU02293.1 - 5.3e-58 195.3 0.0 6e-58 195.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrofolate reductase Metallophos PF00149.28 EHU02294.1 - 1.7e-14 54.8 0.4 1.9e-13 51.4 0.1 2.5 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EHU02294.1 - 1.1e-05 25.6 0.0 1.7e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FBPase_2 PF06874.11 EHU02294.1 - 0.053 11.8 0.1 0.22 9.8 0.0 1.7 2 0 0 2 2 2 0 Firmicute fructose-1,6-bisphosphatase DUF525 PF04379.14 EHU02295.1 - 7.5e-34 115.8 0.3 9.2e-34 115.6 0.3 1.1 1 0 0 1 1 1 1 ApaG domain Dirigent PF03018.14 EHU02295.1 - 0.021 14.7 0.1 2 8.2 0.0 2.1 2 0 0 2 2 2 0 Dirigent-like protein DUF4354 PF14263.6 EHU02295.1 - 0.074 12.9 0.0 0.093 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4354) RrnaAD PF00398.20 EHU02296.1 - 2.2e-79 266.3 0.0 2.4e-79 266.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase NodS PF05401.11 EHU02296.1 - 0.19 11.3 0.0 1.2 8.7 0.0 2.2 3 0 0 3 3 3 0 Nodulation protein S (NodS) PdxA PF04166.12 EHU02297.1 - 7.1e-109 363.6 0.0 8.7e-109 363.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA Rotamase PF00639.21 EHU02298.1 - 5.5e-50 168.3 0.0 3.2e-27 95.3 0.0 3.1 3 0 0 3 3 3 2 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EHU02298.1 - 3.9e-49 166.0 0.0 3.6e-27 95.2 0.0 2.6 2 0 0 2 2 2 2 PPIC-type PPIASE domain SurA_N PF09312.11 EHU02298.1 - 2.2e-43 147.1 7.1 2.2e-43 147.1 7.1 2.0 2 0 0 2 2 2 1 SurA N-terminal domain Rotamase_2 PF13145.6 EHU02298.1 - 3e-19 70.0 1.7 1.5e-08 35.5 0.0 3.0 3 1 0 3 3 3 2 PPIC-type PPIASE domain SurA_N_3 PF13624.6 EHU02298.1 - 2.1e-14 53.6 4.7 4.4e-14 52.6 4.7 1.6 1 0 0 1 1 1 1 SurA N-terminal domain SurA_N_2 PF13623.6 EHU02298.1 - 3.1e-08 33.6 5.8 4e-08 33.2 4.3 1.9 1 1 0 1 1 1 1 SurA N-terminal domain Trigger_C PF05698.14 EHU02298.1 - 0.002 18.2 2.8 0.0082 16.2 2.1 2.4 1 1 0 1 1 1 1 Bacterial trigger factor protein (TF) C-terminus PhageMin_Tail PF10145.9 EHU02298.1 - 6.7 6.5 9.9 0.87 9.4 4.1 2.4 2 1 0 3 3 3 0 Phage-related minor tail protein LptD PF04453.14 EHU02299.1 - 1.2e-98 330.9 34.2 1.2e-98 330.9 34.2 2.0 1 1 1 2 2 2 2 LPS transport system D OstA PF03968.14 EHU02299.1 - 5e-27 94.3 0.2 1.2e-26 93.1 0.2 1.7 1 0 0 1 1 1 1 OstA-like protein TerB PF05099.13 EHU02300.1 - 1.1e-11 44.9 0.1 2.2e-11 43.9 0.1 1.5 1 0 0 1 1 1 1 Tellurite resistance protein TerB DnaJ PF00226.31 EHU02300.1 - 1.5e-09 37.9 0.1 2.8e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain HTH_10 PF04967.12 EHU02300.1 - 0.0043 16.8 0.0 0.47 10.3 0.0 2.7 2 0 0 2 2 2 2 HTH DNA binding domain PseudoU_synth_2 PF00849.22 EHU02301.1 - 3.3e-29 102.0 0.0 4e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase RRM_7 PF16367.5 EHU02301.1 - 0.052 13.7 0.0 0.15 12.2 0.0 1.7 1 1 1 2 2 2 0 RNA recognition motif DinI PF06183.13 EHU02301.1 - 0.11 12.8 0.0 0.29 11.5 0.0 1.7 2 0 0 2 2 2 0 DinI-like family RapA_C PF12137.8 EHU02302.1 - 1.3e-154 514.6 0.2 1.9e-154 514.0 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase recycling family C-terminal Tudor_RapA PF18337.1 EHU02302.1 - 5.9e-26 90.4 0.0 1.3e-25 89.3 0.0 1.7 1 0 0 1 1 1 1 RapA N-terminal Tudor like domain Tudor_1_RapA PF18339.1 EHU02302.1 - 8.5e-24 83.3 0.0 1.7e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 RapA N-terminal Tudor like domain 1 SNF2_N PF00176.23 EHU02302.1 - 1.9e-20 72.9 0.0 3.3e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EHU02302.1 - 2.9e-16 59.8 0.0 3.2e-15 56.4 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EHU02302.1 - 3.4e-11 43.4 0.0 1.3e-10 41.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EHU02302.1 - 2e-05 24.4 0.0 7.4e-05 22.6 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.6 EHU02302.1 - 0.0052 15.7 0.0 0.046 12.6 0.0 2.3 2 1 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 Helicase_RecD PF05127.14 EHU02302.1 - 0.0075 16.1 0.0 0.023 14.6 0.0 1.8 1 0 0 1 1 1 1 Helicase AAA_22 PF13401.6 EHU02302.1 - 0.14 12.5 0.3 1.6 9.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain Phage_T7_Capsid PF05396.11 EHU02302.1 - 3.9 7.8 4.5 0.75 10.2 0.3 2.0 3 0 0 3 3 3 0 Phage T7 capsid assembly protein DNA_pol_B PF00136.21 EHU02303.1 - 1.2e-42 146.2 0.0 3.5e-33 115.0 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EHU02303.1 - 1.4e-11 44.1 0.0 4.2e-05 22.8 0.0 2.5 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain DNA_pol_B_2 PF03175.13 EHU02303.1 - 4.3e-05 22.6 0.0 0.0041 16.0 0.0 2.1 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral GGDEF_2 PF17853.1 EHU02303.1 - 0.0036 17.6 0.6 1.4 9.2 0.0 4.0 3 1 1 4 4 4 1 GGDEF-like domain P63C PF10546.9 EHU02303.1 - 0.061 13.9 0.2 0.14 12.8 0.2 1.5 1 0 0 1 1 1 0 P63C domain Glyco_transf_4 PF13439.6 EHU02303.1 - 0.084 12.9 0.1 8.3 6.4 0.0 2.8 2 0 0 2 2 2 0 Glycosyltransferase Family 4 SNARE_assoc PF09335.11 EHU02304.1 - 1.9e-16 60.6 1.2 1.9e-16 60.6 1.2 2.4 1 1 1 2 2 2 1 SNARE associated Golgi protein DUF4381 PF14316.6 EHU02304.1 - 3.6 7.8 9.5 8.4 6.6 8.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4381) ABC_tran PF00005.27 EHU02305.1 - 2.1e-34 119.0 0.0 3.3e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EHU02305.1 - 4.1e-11 43.2 0.2 1.3e-06 28.4 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EHU02305.1 - 8.5e-05 22.1 0.0 0.0012 18.3 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EHU02305.1 - 0.0003 21.2 0.4 0.0006 20.2 0.4 1.6 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EHU02305.1 - 0.00069 19.6 0.1 0.0014 18.6 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase SbcCD_C PF13558.6 EHU02305.1 - 0.0012 19.0 0.1 0.033 14.4 0.1 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EHU02305.1 - 0.0023 17.6 0.0 0.0043 16.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EHU02305.1 - 0.0026 18.0 0.1 0.017 15.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 EHU02305.1 - 0.0058 16.6 1.3 0.87 9.5 0.1 3.0 2 1 1 3 3 3 1 NACHT domain MMR_HSR1 PF01926.23 EHU02305.1 - 0.012 15.7 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.6 EHU02305.1 - 0.02 15.4 0.0 0.029 14.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EHU02305.1 - 0.033 13.7 0.0 0.47 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EHU02305.1 - 0.034 13.5 0.2 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MeaB PF03308.16 EHU02305.1 - 0.043 12.8 0.0 0.073 12.0 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 EHU02305.1 - 0.048 13.4 0.0 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EHU02305.1 - 0.067 12.9 0.5 0.55 9.9 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 EHU02305.1 - 0.1 12.9 0.1 0.74 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EHU02305.1 - 0.1 12.6 0.3 0.27 11.3 0.3 1.6 2 0 0 2 2 2 0 Dynamin family DUF87 PF01935.17 EHU02305.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_18 PF13238.6 EHU02305.1 - 0.18 12.4 0.0 0.83 10.2 0.0 2.1 1 1 1 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 EHU02305.1 - 0.36 10.5 1.0 0.78 9.4 0.1 2.0 2 2 1 3 3 3 0 Cytidylate kinase BPD_transp_1 PF00528.22 EHU02306.1 - 6e-16 58.7 19.3 1.2e-09 38.2 6.2 3.4 2 2 1 3 3 3 2 Binding-protein-dependent transport system inner membrane component SBP_bac_8 PF13416.6 EHU02307.1 - 1.9e-19 70.6 3.0 2.5e-19 70.2 3.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 EHU02307.1 - 5.2e-18 65.4 2.2 6.5e-18 65.0 2.2 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 EHU02307.1 - 2.7e-16 60.4 6.5 4.1e-16 59.8 6.5 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 EHU02307.1 - 3.2e-15 56.5 0.1 4.1e-15 56.2 0.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Imm27 PF15590.6 EHU02307.1 - 0.16 11.8 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 27 MFS_1 PF07690.16 EHU02308.1 - 1.6e-32 112.8 56.8 1.4e-26 93.2 37.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EHU02308.1 - 1.6e-05 23.9 27.7 0.00086 18.3 14.8 2.3 1 1 0 2 2 2 2 MFS_1 like family Aconitase_C PF00694.19 EHU02309.1 - 1.1e-39 135.8 0.0 1.4e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase PF00330.20 EHU02310.1 - 1.4e-163 545.2 0.3 1.6e-163 545.0 0.3 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Nodulin PF02451.15 EHU02310.1 - 0.2 11.1 0.3 0.42 10.1 0.3 1.5 1 0 0 1 1 1 0 Nodulin Iso_dh PF00180.20 EHU02311.1 - 7.7e-135 449.5 0.0 8.7e-135 449.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HMGL-like PF00682.19 EHU02312.1 - 2.7e-105 351.7 4.0 4e-105 351.1 4.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 EHU02312.1 - 3.7e-36 124.0 0.4 7.3e-36 123.0 0.4 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain DUF3235 PF11574.8 EHU02312.1 - 0.085 13.7 0.1 70 4.4 0.0 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3235) TPP_enzyme_N PF02776.18 EHU02313.1 - 7.3e-59 198.2 0.1 1.5e-56 190.7 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EHU02313.1 - 1.3e-49 167.9 0.0 5.5e-48 162.6 0.0 2.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EHU02313.1 - 6e-49 165.3 0.0 1.1e-48 164.5 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 EHU02313.1 - 0.0022 17.8 0.1 0.0058 16.4 0.0 1.7 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PPS_PS PF02006.16 EHU02313.1 - 0.0065 16.0 0.0 0.16 11.5 0.0 2.3 2 0 0 2 2 2 1 Phosphopantothenate/pantothenate synthetase ASXH PF13919.6 EHU02313.1 - 0.086 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Asx homology domain ALS_ss_C PF10369.9 EHU02314.1 - 1.4e-24 86.0 1.2 1.8e-23 82.6 0.5 2.1 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 EHU02314.1 - 3.6e-15 55.4 0.0 6.2e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 EHU02314.1 - 9.1e-15 54.3 0.1 1.9e-14 53.3 0.1 1.6 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 EHU02314.1 - 8.9e-06 26.2 0.2 4.3e-05 24.0 0.1 2.0 2 0 0 2 2 2 1 ACT domain HTH_Tnp_1 PF01527.20 EHU02315.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU02315.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU02315.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU02315.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHU02316.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHU02317.1 - 7.5e-97 324.2 3.7 4.5e-96 321.6 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU02317.1 - 3.4e-16 59.2 0.1 1.3e-15 57.3 0.1 2.1 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU02317.1 - 1.6e-14 54.1 1.5 3.4e-14 52.9 1.5 1.6 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU02317.1 - 8.7e-11 42.4 9.0 1.9e-10 41.4 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Phage_HK97_TLTM PF06120.11 EHU02317.1 - 0.011 14.9 0.8 0.021 14.0 0.8 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHU02317.1 - 0.02 15.2 4.2 0.084 13.2 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Exonuc_VII_L PF02601.15 EHU02317.1 - 0.032 13.8 2.2 0.04 13.5 1.0 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit UME PF08064.13 EHU02317.1 - 0.033 14.1 0.3 20 5.1 0.0 3.1 2 1 1 3 3 3 0 UME (NUC010) domain Troponin PF00992.20 EHU02317.1 - 0.044 14.1 2.8 0.078 13.3 2.8 1.3 1 0 0 1 1 1 0 Troponin Tho2 PF11262.8 EHU02317.1 - 0.05 12.8 0.6 0.081 12.1 0.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FUSC PF04632.12 EHU02317.1 - 0.05 12.1 7.4 0.077 11.5 7.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family FAM184 PF15665.5 EHU02317.1 - 0.052 13.3 8.0 0.082 12.7 8.0 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B HalX PF08663.10 EHU02317.1 - 0.13 12.6 2.4 0.34 11.3 2.4 1.7 1 0 0 1 1 1 0 HalX domain LXG PF04740.12 EHU02317.1 - 0.15 11.8 2.8 0.35 10.5 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHU02317.1 - 0.2 11.5 11.1 0.31 10.8 11.1 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DHR10 PF18595.1 EHU02317.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Zn-ribbon_8 PF09723.10 EHU02317.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF1192 PF06698.11 EHU02317.1 - 0.54 10.3 5.3 3.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHU02317.1 - 0.83 8.8 3.0 1.2 8.3 3.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein CREPT PF16566.5 EHU02317.1 - 1.2 9.3 5.6 2.7 8.1 5.6 1.5 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour HAUS-augmin3 PF14932.6 EHU02317.1 - 2 7.9 8.1 4.3 6.8 8.1 1.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHU02317.1 - 4.4 7.6 8.6 8.7 6.7 8.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) LacI PF00356.21 EHU02318.1 - 2.5e-19 68.8 0.7 5.3e-19 67.8 0.7 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_1 PF00532.21 EHU02318.1 - 1.6e-12 47.5 0.0 2e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 EHU02318.1 - 1.2e-08 35.5 0.0 2.5e-07 31.2 0.0 2.3 2 1 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_4 PF13407.6 EHU02318.1 - 8.7e-08 32.0 0.0 1.1e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain HTH_3 PF01381.22 EHU02318.1 - 0.016 15.2 0.0 0.046 13.8 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix DDE_3 PF13358.6 EHU02319.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHU02319.1 - 7.6e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHU02319.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHU02319.1 - 3.8e-06 26.5 0.3 3.8e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHU02319.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHU02319.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHU02319.1 - 0.088 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHU02319.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 MraZ PF02381.18 EHU02320.1 - 1.7e-44 149.7 0.2 1.9e-21 75.8 0.0 2.0 2 0 0 2 2 2 2 MraZ protein, putative antitoxin-like Methyltransf_5 PF01795.19 EHU02321.1 - 1.9e-118 395.5 0.0 2.2e-118 395.3 0.0 1.0 1 0 0 1 1 1 1 MraW methylase family Methyltransf_31 PF13847.6 EHU02321.1 - 0.00017 21.4 0.0 0.017 14.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_24 PF13578.6 EHU02321.1 - 0.0011 19.9 0.0 0.0047 17.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EHU02321.1 - 0.0058 17.3 0.0 0.24 12.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain FtsL PF04999.13 EHU02322.1 - 3.1e-35 120.0 1.3 3.5e-35 119.9 1.3 1.0 1 0 0 1 1 1 1 Cell division protein FtsL DivIC PF04977.15 EHU02322.1 - 0.0086 15.8 0.5 0.011 15.4 0.5 1.1 1 0 0 1 1 1 1 Septum formation initiator Transpeptidase PF00905.22 EHU02323.1 - 4e-81 272.6 0.0 5e-81 272.3 0.0 1.1 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain PBP_dimer PF03717.15 EHU02323.1 - 1.3e-19 71.3 0.0 4.7e-18 66.2 0.0 2.3 1 1 0 1 1 1 1 Penicillin-binding Protein dimerisation domain DUF1616 PF07760.11 EHU02323.1 - 0.066 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Mur_ligase_M PF08245.12 EHU02324.1 - 5.2e-51 173.4 0.0 7.3e-51 172.9 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 EHU02324.1 - 4.4e-26 91.0 0.0 2.3e-25 88.7 0.0 2.2 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Mur_ligase PF01225.25 EHU02324.1 - 5.5e-14 52.3 1.0 1.6e-13 50.8 0.4 2.1 2 0 0 2 2 2 1 Mur ligase family, catalytic domain Mur_ligase_M PF08245.12 EHU02325.1 - 1.8e-48 165.1 0.0 4.5e-48 163.8 0.0 1.7 2 0 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.21 EHU02325.1 - 3.3e-16 59.3 0.1 2.9e-14 53.1 0.0 2.6 1 1 1 2 2 2 1 Mur ligase family, glutamate ligase domain Mur_ligase PF01225.25 EHU02325.1 - 5.6e-10 39.4 0.0 1.8e-09 37.8 0.0 1.9 1 0 0 1 1 1 1 Mur ligase family, catalytic domain LpxD PF04613.14 EHU02325.1 - 0.06 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD Glycos_transf_4 PF00953.21 EHU02326.1 - 9.1e-34 116.7 15.9 9.1e-34 116.7 15.9 2.1 3 0 0 3 3 3 1 Glycosyl transferase family 4 MraY_sig1 PF10555.9 EHU02326.1 - 1e-05 24.8 3.3 1e-05 24.8 3.3 3.0 3 0 0 3 3 3 1 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 Mur_ligase_M PF08245.12 EHU02327.1 - 3.8e-29 102.1 0.0 6.3e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 EHU02327.1 - 5e-11 42.7 0.0 4.4e-10 39.7 0.0 2.5 3 0 0 3 3 3 1 Mur ligase family, glutamate ligase domain NAD_binding_7 PF13241.6 EHU02327.1 - 0.024 15.1 0.0 0.075 13.5 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding FTSW_RODA_SPOVE PF01098.19 EHU02328.1 - 6.8e-125 416.8 21.1 8e-125 416.5 21.1 1.0 1 0 0 1 1 1 1 Cell cycle protein DUF1422 PF07226.11 EHU02328.1 - 2.6 8.1 8.7 0.49 10.4 3.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1422) Glyco_transf_28 PF03033.20 EHU02329.1 - 4.6e-48 162.8 0.1 1.1e-47 161.5 0.1 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.16 EHU02329.1 - 1.3e-39 135.8 0.0 1.9e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_4 PF13439.6 EHU02329.1 - 6.5e-09 36.0 0.2 6.2e-08 32.8 0.1 2.2 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 EHU02329.1 - 1.3e-07 32.1 0.1 1.3e-05 25.7 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EHU02329.1 - 1.2e-05 25.8 5.4 9.3e-05 22.9 5.2 2.4 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.20 EHU02329.1 - 0.041 13.4 0.0 0.7 9.4 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 EHU02329.1 - 0.067 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like Mur_ligase PF01225.25 EHU02330.1 - 1.3e-30 105.5 0.9 2.5e-30 104.6 0.2 1.9 2 0 0 2 2 2 1 Mur ligase family, catalytic domain Mur_ligase_M PF08245.12 EHU02330.1 - 1.2e-27 97.2 0.0 1.6e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 EHU02330.1 - 1.5e-20 73.2 0.0 7.5e-20 71.0 0.0 2.2 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Dala_Dala_lig_C PF07478.13 EHU02331.1 - 5.1e-65 218.8 0.0 6.3e-65 218.5 0.0 1.1 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 EHU02331.1 - 1e-19 70.9 0.4 2.9e-18 66.2 0.4 2.4 1 1 0 1 1 1 1 D-ala D-ala ligase N-terminus ATP-grasp_4 PF13535.6 EHU02331.1 - 4.4e-09 36.1 0.0 3.8e-08 33.1 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 EHU02331.1 - 9.3e-06 25.3 0.0 1.4e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 EHU02331.1 - 0.01 15.9 0.0 0.019 15.0 0.0 1.4 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 EHU02331.1 - 0.093 12.5 0.0 1.2 8.9 0.0 2.3 1 1 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon GSP_synth PF03738.14 EHU02331.1 - 0.16 11.1 0.0 0.31 10.2 0.0 1.5 1 0 0 1 1 1 0 Glutathionylspermidine synthase preATP-grasp FtsQ PF03799.15 EHU02332.1 - 1.1e-24 87.5 0.0 1.8e-24 86.8 0.0 1.4 1 0 0 1 1 1 1 Cell division protein FtsQ POTRA_1 PF08478.10 EHU02332.1 - 1.3e-22 79.9 0.1 3.6e-22 78.4 0.1 1.8 1 0 0 1 1 1 1 POTRA domain, FtsQ-type FtsA PF14450.6 EHU02333.1 - 2.1e-32 111.6 1.4 1.9e-23 82.8 0.1 2.1 2 0 0 2 2 2 2 Cell division protein FtsA SHS2_FTSA PF02491.20 EHU02333.1 - 2.7e-30 104.6 2.2 5.6e-30 103.6 2.2 1.6 1 0 0 1 1 1 1 SHS2 domain inserted in FTSA MreB_Mbl PF06723.13 EHU02333.1 - 3.4e-10 39.2 0.4 3.4e-10 39.2 0.4 1.8 2 1 1 3 3 3 1 MreB/Mbl protein PilM_2 PF11104.8 EHU02333.1 - 4.2e-10 39.2 0.4 1.5e-06 27.5 0.1 2.6 2 1 0 2 2 2 2 Type IV pilus assembly protein PilM; EutA PF06277.11 EHU02333.1 - 0.00092 18.2 0.4 0.0025 16.8 0.1 1.8 2 0 0 2 2 2 1 Ethanolamine utilisation protein EutA DDR PF08841.10 EHU02333.1 - 0.0018 17.3 0.9 0.0058 15.7 0.4 1.8 1 1 1 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Actin PF00022.19 EHU02333.1 - 0.017 13.8 0.3 4.5 5.8 0.1 2.5 3 0 0 3 3 3 0 Actin Hydantoinase_A PF01968.18 EHU02333.1 - 0.055 12.7 0.5 0.13 11.5 0.1 1.9 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase HSP70 PF00012.20 EHU02333.1 - 0.079 11.1 0.6 0.26 9.4 0.1 1.9 2 0 0 2 2 2 0 Hsp70 protein Tubulin PF00091.25 EHU02334.1 - 1.3e-42 146.2 0.9 1.9e-42 145.7 0.9 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 EHU02334.1 - 2.3e-37 127.2 1.0 6.1e-37 125.8 1.0 1.8 1 0 0 1 1 1 1 FtsZ family, C-terminal domain NAD_binding_10 PF13460.6 EHU02334.1 - 0.0036 17.2 0.1 0.0094 15.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)H-binding Tubulin_2 PF13809.6 EHU02334.1 - 0.053 12.7 6.9 0.81 8.8 1.8 2.3 1 1 1 2 2 2 0 Tubulin like HATPase_c PF02518.26 EHU02334.1 - 0.071 13.6 0.1 0.21 12.1 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LpxC PF03331.13 EHU02335.1 - 2.7e-107 358.3 0.0 3.1e-107 358.1 0.0 1.0 1 0 0 1 1 1 1 UDP-3-O-acyl N-acetylglycosamine deacetylase SecM PF06558.12 EHU02336.1 - 4.2e-45 153.4 1.5 4.8e-45 153.2 1.5 1.0 1 0 0 1 1 1 1 Secretion monitor precursor protein (SecM) DUF2547 PF10818.8 EHU02336.1 - 0.0019 19.1 0.1 0.011 16.6 0.1 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2547) SecA_DEAD PF07517.14 EHU02337.1 - 3.9e-132 439.9 0.4 6.5e-132 439.2 0.4 1.4 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_SW PF07516.13 EHU02337.1 - 4.3e-69 232.6 5.4 4.7e-69 232.5 3.8 1.9 2 0 0 2 2 2 1 SecA Wing and Scaffold domain SecA_PP_bind PF01043.20 EHU02337.1 - 4.7e-40 136.7 0.2 1.7e-39 134.9 0.2 2.0 1 0 0 1 1 1 1 SecA preprotein cross-linking domain SEC-C PF02810.15 EHU02337.1 - 7.4e-11 41.7 9.7 1.2e-10 41.1 9.7 1.3 1 0 0 1 1 1 1 SEC-C motif DEAD PF00270.29 EHU02337.1 - 0.00058 19.7 0.0 0.0025 17.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2175 PF09943.9 EHU02337.1 - 0.035 14.4 0.3 0.14 12.4 0.3 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) Helicase_C PF00271.31 EHU02337.1 - 0.15 12.4 2.3 0.79 10.1 0.0 2.8 2 0 0 2 2 2 0 Helicase conserved C-terminal domain NUDIX PF00293.28 EHU02338.1 - 1.3e-19 70.5 0.5 1.4e-19 70.4 0.5 1.0 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 EHU02338.1 - 2.8e-17 62.7 0.1 3.2e-17 62.5 0.1 1.0 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.6 EHU02338.1 - 0.015 14.9 0.0 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 Nucleotide hydrolase YacG PF03884.14 EHU02339.1 - 1e-24 86.0 4.5 1.3e-24 85.6 4.5 1.2 1 0 0 1 1 1 1 DNA gyrase inhibitor YacG zf-ribbon_3 PF13248.6 EHU02339.1 - 0.02 14.3 0.1 0.02 14.3 0.1 1.6 2 0 0 2 2 2 0 zinc-ribbon domain ZapD PF07072.11 EHU02340.1 - 3.5e-77 258.9 0.6 4e-77 258.7 0.6 1.0 1 0 0 1 1 1 1 Cell division protein CoaE PF01121.20 EHU02341.1 - 6.1e-69 231.3 0.1 7.1e-69 231.0 0.1 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_28 PF13521.6 EHU02341.1 - 5.3e-05 23.5 2.5 0.00061 20.1 2.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EHU02341.1 - 8.8e-05 22.7 0.8 0.00058 20.0 0.8 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EHU02341.1 - 0.00024 21.7 0.6 0.0026 18.3 0.6 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EHU02341.1 - 0.0066 16.9 0.2 0.036 14.5 0.2 2.0 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 EHU02341.1 - 0.0066 16.6 0.4 4.2 7.5 0.0 2.2 2 0 0 2 2 2 2 Shikimate kinase Zeta_toxin PF06414.12 EHU02341.1 - 0.0094 15.2 0.2 0.06 12.6 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_29 PF13555.6 EHU02341.1 - 0.015 15.0 0.1 0.035 13.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 EHU02341.1 - 0.021 14.5 0.1 0.49 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EHU02341.1 - 0.052 13.8 1.5 0.44 10.8 1.5 2.4 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 EHU02341.1 - 0.056 12.8 0.3 0.11 11.8 0.1 1.5 2 0 0 2 2 2 0 KaiC APS_kinase PF01583.20 EHU02341.1 - 0.08 12.8 0.3 0.39 10.6 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_16 PF13191.6 EHU02341.1 - 0.15 12.4 4.3 0.76 10.1 4.3 2.0 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EHU02341.1 - 0.49 10.9 3.8 2.7 8.5 3.8 2.0 1 1 0 1 1 1 0 ABC transporter Cytidylate_kin2 PF13189.6 EHU02341.1 - 0.49 10.5 3.6 13 5.8 3.6 2.7 1 1 0 1 1 1 0 Cytidylate kinase-like family IMPDH PF00478.25 EHU02342.1 - 1.7e-77 260.8 0.3 2.2e-77 260.4 0.3 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EHU02342.1 - 0.00089 18.4 1.2 0.0017 17.5 1.2 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase T2SSF PF00482.23 EHU02343.1 - 3.3e-59 198.3 5.0 1.2e-30 106.0 0.2 2.4 3 0 0 3 3 3 2 Type II secretion system (T2SS), protein F T2SSE PF00437.20 EHU02344.1 - 1.1e-77 260.8 0.1 1.4e-77 260.4 0.1 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 EHU02344.1 - 0.0063 16.3 0.1 0.022 14.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EHU02344.1 - 0.0097 16.3 0.9 0.024 15.0 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EHU02344.1 - 0.01 16.1 0.1 0.039 14.2 0.1 1.9 2 0 0 2 2 2 0 AAA domain Microtub_bd PF16796.5 EHU02344.1 - 0.012 15.5 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Microtubule binding AAA_19 PF13245.6 EHU02344.1 - 0.055 13.8 0.3 0.18 12.1 0.1 1.9 2 0 0 2 2 2 0 AAA domain Kinesin PF00225.23 EHU02344.1 - 0.059 12.3 0.0 0.091 11.7 0.0 1.2 1 0 0 1 1 1 0 Kinesin motor domain AAA_25 PF13481.6 EHU02344.1 - 0.072 12.7 0.1 0.17 11.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EHU02344.1 - 0.13 12.1 0.1 0.32 10.7 0.0 1.6 1 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EHU02344.1 - 0.16 11.7 0.1 0.36 10.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ResIII PF04851.15 EHU02344.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 EHU02344.1 - 0.25 10.9 0.0 0.66 9.5 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region N_methyl PF07963.12 EHU02345.1 - 3.2e-09 35.9 1.2 6.2e-09 35.1 1.2 1.5 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif Pilin PF00114.19 EHU02345.1 - 8.1e-05 23.5 0.2 9.8e-05 23.2 0.2 1.1 1 0 0 1 1 1 1 Pilin (bacterial filament) DUF2499 PF10693.9 EHU02345.1 - 0.0049 17.1 0.1 0.035 14.4 0.0 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF2499) DDE_3 PF13358.6 EHU02346.1 - 6.1e-23 81.2 0.0 9.9e-23 80.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.6 EHU02346.1 - 1.1e-10 41.0 1.0 3.6e-09 36.2 0.1 3.1 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 EHU02346.1 - 4.2e-09 36.9 1.1 2.8e-08 34.3 0.3 2.5 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 EHU02346.1 - 3.9e-07 30.0 1.2 1.1e-06 28.6 0.3 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_33 PF13592.6 EHU02346.1 - 3.1e-06 26.7 5.1 4.4e-06 26.2 0.3 2.9 3 0 0 3 3 3 1 Winged helix-turn helix HTH_28 PF13518.6 EHU02346.1 - 1.4e-05 25.1 0.3 0.0002 21.4 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHU02346.1 - 0.031 14.8 0.2 0.061 13.8 0.2 1.4 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 HTH_38 PF13936.6 EHU02346.1 - 0.054 13.3 0.6 0.16 11.8 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain QRPTase_C PF01729.19 EHU02347.1 - 1.3e-58 197.5 0.2 1.7e-58 197.2 0.2 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 EHU02347.1 - 8.3e-26 89.9 0.0 3.9e-24 84.5 0.0 2.8 2 1 1 3 3 3 1 Quinolinate phosphoribosyl transferase, N-terminal domain Biotin_lipoyl_2 PF13533.6 EHU02347.1 - 0.021 14.7 0.0 0.062 13.1 0.0 1.7 1 0 0 1 1 1 0 Biotin-lipoyl like IMPDH PF00478.25 EHU02347.1 - 0.1 11.6 0.2 0.15 11.1 0.2 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain DUF816 PF05674.12 EHU02347.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF816) Amidase_2 PF01510.25 EHU02348.1 - 2.5e-29 102.3 0.0 3e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase AmpE PF17113.5 EHU02349.1 - 7.1e-153 507.9 13.5 8e-153 507.8 13.5 1.0 1 0 0 1 1 1 1 Regulatory signalling modulator protein AmpE CobD_Cbib PF03186.13 EHU02349.1 - 0.14 11.4 9.0 2.2 7.4 8.7 2.6 1 1 0 1 1 1 0 CobD/Cbib protein Glyco_hydro_43 PF04616.14 EHU02350.1 - 3.9e-65 220.0 0.8 4.3e-65 219.9 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 G-gamma PF00631.22 EHU02350.1 - 0.0049 16.8 0.8 0.99 9.5 0.1 2.8 3 0 0 3 3 3 2 GGL domain MFS_2 PF13347.6 EHU02351.1 - 6.3e-106 354.5 27.0 7.1e-106 354.3 27.0 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 EHU02351.1 - 1.5e-08 34.0 25.2 1.5e-08 34.0 25.2 2.8 1 1 0 2 2 2 1 Major Facilitator Superfamily ATG22 PF11700.8 EHU02351.1 - 0.02 13.5 14.2 0.039 12.6 0.2 3.6 3 1 1 4 4 4 0 Vacuole effluxer Atg22 like AA_permease PF00324.21 EHU02352.1 - 3.5e-121 405.1 46.1 3.9e-121 405.0 46.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EHU02352.1 - 2.1e-40 138.8 50.8 2.9e-40 138.4 50.8 1.1 1 0 0 1 1 1 1 Amino acid permease GntR PF00392.21 EHU02353.1 - 5.5e-23 80.4 0.4 1.1e-22 79.4 0.4 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family FCD PF07729.12 EHU02353.1 - 4.5e-19 69.1 12.0 4.5e-19 69.1 12.0 1.7 2 0 0 2 2 2 1 FCD domain MarR PF01047.22 EHU02353.1 - 0.00016 21.5 0.4 0.00098 19.0 0.1 2.3 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.7 EHU02353.1 - 0.0005 19.9 0.3 0.002 18.0 0.1 2.1 2 0 0 2 2 1 1 MarR family TrmB PF01978.19 EHU02353.1 - 0.00073 19.4 0.1 0.015 15.2 0.0 2.6 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.12 EHU02353.1 - 0.0018 18.2 0.0 0.0048 16.8 0.0 1.7 1 0 0 1 1 1 1 HTH domain PaaX PF07848.12 EHU02353.1 - 0.0023 18.1 0.1 0.0058 16.8 0.1 1.6 1 0 0 1 1 1 1 PaaX-like protein HTH_24 PF13412.6 EHU02353.1 - 0.0024 17.4 0.0 0.0052 16.3 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_DeoR PF08220.12 EHU02353.1 - 0.0034 17.1 0.0 0.008 15.9 0.0 1.6 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_28 PF13518.6 EHU02353.1 - 0.0059 16.7 0.1 0.02 15.0 0.1 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain Rrf2 PF02082.20 EHU02353.1 - 0.008 16.5 0.0 0.019 15.3 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator Fe_dep_repress PF01325.19 EHU02353.1 - 0.018 15.2 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_29 PF13551.6 EHU02353.1 - 0.038 14.0 0.6 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn helix HTH_20 PF12840.7 EHU02353.1 - 0.045 13.8 1.2 0.16 12.0 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_10 PF04967.12 EHU02353.1 - 0.084 12.7 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 HTH DNA binding domain PDH_E1_M PF17831.1 EHU02354.1 - 3.1e-104 347.5 0.2 5.2e-104 346.8 0.2 1.4 1 0 0 1 1 1 1 Pyruvate dehydrogenase E1 component middle domain Transketolase_N PF00456.21 EHU02354.1 - 1.4e-15 57.1 0.0 5.2e-08 32.2 0.0 2.3 2 0 0 2 2 2 2 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 EHU02354.1 - 0.089 12.7 0.0 0.37 10.7 0.0 2.1 2 0 0 2 2 2 0 Transketolase, C-terminal domain 2-oxoacid_dh PF00198.23 EHU02355.1 - 4.3e-79 265.2 0.0 6.1e-79 264.7 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EHU02355.1 - 1.9e-65 216.7 34.6 1.9e-22 78.9 7.1 3.4 3 0 0 3 3 3 3 Biotin-requiring enzyme E3_binding PF02817.17 EHU02355.1 - 4.9e-16 58.8 0.5 1.7e-15 57.1 0.2 2.2 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 EHU02355.1 - 5.7e-15 54.9 14.4 0.03 14.1 0.0 6.5 6 0 0 6 6 6 6 Biotin-lipoyl like RnfC_N PF13375.6 EHU02355.1 - 4.4e-12 45.8 14.8 0.0013 18.6 1.1 4.1 3 2 0 3 3 3 3 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 EHU02355.1 - 1.7e-08 34.4 16.9 0.006 16.5 1.3 3.7 3 0 0 3 3 3 3 Glycine cleavage H-protein HlyD_D23 PF16576.5 EHU02355.1 - 2.8e-06 26.7 9.2 0.31 10.2 0.0 4.9 3 3 3 6 6 6 3 Barrel-sandwich domain of CusB or HlyD membrane-fusion NQRA PF05896.11 EHU02355.1 - 8.4e-06 25.4 12.7 0.065 12.7 0.4 3.5 1 1 1 3 3 3 3 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) PTS_EIIA_1 PF00358.20 EHU02355.1 - 7.2e-05 22.5 12.2 5.6 6.7 0.2 6.2 3 3 3 6 6 6 2 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 PYNP_C PF07831.13 EHU02355.1 - 0.0002 20.9 12.6 13 5.6 0.1 6.3 4 2 2 6 6 6 1 Pyrimidine nucleoside phosphorylase C-terminal domain HlyD_3 PF13437.6 EHU02355.1 - 0.013 16.2 11.0 5.5 7.7 0.0 5.2 3 3 3 6 6 6 0 HlyD family secretion protein DUF1223 PF06764.11 EHU02355.1 - 0.013 15.5 0.0 0.035 14.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) Adeno_knob PF00541.17 EHU02355.1 - 0.014 15.2 0.0 36 4.0 0.0 3.3 3 0 0 3 3 3 0 Adenoviral fibre protein (knob domain) Pyr_redox_2 PF07992.14 EHU02356.1 - 2.4e-64 217.4 4.4 3.2e-64 217.0 4.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EHU02356.1 - 9.2e-36 122.5 0.1 2.1e-35 121.3 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EHU02356.1 - 8.5e-19 67.9 4.1 4.8e-16 59.1 0.8 3.0 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EHU02356.1 - 1e-09 38.1 0.4 8.8e-06 25.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EHU02356.1 - 3.8e-09 36.1 1.1 2.1e-08 33.6 0.3 2.5 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EHU02356.1 - 3.2e-08 33.4 1.7 3.9e-08 33.1 0.5 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EHU02356.1 - 2.9e-06 26.7 1.1 0.049 12.9 0.1 3.2 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 EHU02356.1 - 1.8e-05 24.9 3.7 0.0012 19.0 0.2 3.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EHU02356.1 - 3.5e-05 22.7 3.2 0.0018 17.1 0.1 2.7 2 1 1 3 3 3 2 HI0933-like protein FAD_binding_2 PF00890.24 EHU02356.1 - 4.4e-05 22.7 4.8 0.00013 21.2 0.3 2.8 3 1 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 EHU02356.1 - 0.00015 21.1 0.1 0.00036 19.8 0.1 1.7 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 EHU02356.1 - 0.00022 20.6 0.4 0.0007 18.9 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.18 EHU02356.1 - 0.0029 17.5 1.2 1.1 9.1 0.1 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EHU02356.1 - 0.013 14.9 0.0 2.9 7.2 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 EHU02356.1 - 0.03 13.4 0.2 0.58 9.2 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 EHU02356.1 - 0.18 11.3 7.1 0.34 10.4 0.6 3.1 2 1 1 3 3 3 0 FAD dependent oxidoreductase LysR_substrate PF03466.20 EHU02357.1 - 1.8e-40 138.6 0.9 3e-40 137.8 0.9 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 EHU02357.1 - 1.4e-18 66.6 2.8 1.4e-18 66.6 2.8 1.7 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family PHTB1_C PF14728.6 EHU02357.1 - 0.024 13.8 0.5 0.033 13.3 0.5 1.1 1 0 0 1 1 1 0 PTHB1 C-terminus HTH_28 PF13518.6 EHU02357.1 - 0.042 14.0 0.1 0.097 12.8 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_30 PF13556.6 EHU02357.1 - 0.049 13.4 0.7 0.17 11.7 0.7 1.9 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Aldo_ket_red PF00248.21 EHU02358.1 - 1.5e-75 254.1 0.0 1.7e-75 253.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Histone_HNS PF00816.21 EHU02358.1 - 0.19 12.6 0.0 0.45 11.4 0.0 1.6 1 0 0 1 1 1 0 H-NS histone family Aconitase_2_N PF06434.13 EHU02359.1 - 8.3e-98 326.0 0.0 1.2e-97 325.5 0.0 1.3 1 0 0 1 1 1 1 Aconitate hydratase 2 N-terminus Aconitase_B_N PF11791.8 EHU02359.1 - 1.3e-67 226.7 0.1 2.2e-67 225.9 0.1 1.4 1 0 0 1 1 1 1 Aconitate B N-terminal domain Aconitase PF00330.20 EHU02359.1 - 8.2e-41 140.5 0.0 5.1e-39 134.6 0.0 2.4 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Ketoacyl-synt_C PF02801.22 EHU02359.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain UPF0231 PF06062.11 EHU02360.1 - 2.4e-41 140.8 2.4 2.6e-41 140.7 2.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0231) DDE_Tnp_1_5 PF13737.6 EHU02361.1 - 4.4e-45 152.6 0.0 7.2e-45 151.9 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 EHU02361.1 - 2.4e-07 30.6 0.0 3.2e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain Cyclophil_like PF04126.13 EHU02361.1 - 0.11 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Cyclophilin-like RVT_3 PF13456.6 EHU02362.1 - 0.12 12.1 0.0 0.13 12.1 0.0 1.0 1 0 0 1 1 1 0 Reverse transcriptase-like MCPsignal PF00015.21 EHU02363.1 - 7.9e-41 139.7 35.9 2.5e-40 138.1 20.9 2.7 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain CHASE3 PF05227.13 EHU02363.1 - 5.2e-34 117.1 4.4 5.2e-34 117.1 4.4 3.4 3 1 0 3 3 3 2 CHASE3 domain HAMP PF00672.25 EHU02363.1 - 2.9e-10 40.4 0.5 2.9e-10 40.4 0.5 4.8 5 1 0 5 5 5 1 HAMP domain MEA1 PF06910.11 EHU02363.1 - 0.39 11.3 4.8 1.7 9.2 4.8 2.1 1 0 0 1 1 1 0 Male enhanced antigen 1 (MEA1) RasGAP_C PF03836.15 EHU02363.1 - 1.5 9.0 8.0 0.37 11.0 2.0 2.8 2 1 0 2 2 2 0 RasGAP C-terminus Glyco_transf_28 PF03033.20 EHU02364.1 - 3.7e-06 27.0 0.0 6.7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.16 EHU02364.1 - 0.012 15.6 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Abhydrolase_1 PF00561.20 EHU02365.1 - 5e-07 29.6 0.0 6.5e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EHU02365.1 - 0.0077 16.9 0.0 0.0085 16.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EHU02365.1 - 0.2 10.9 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 HTH_Tnp_1 PF01527.20 EHU02366.1 - 3.1e-09 37.0 0.0 4.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EHU02366.1 - 0.049 13.4 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EHU02366.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EHU02366.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TnpB_IS66 PF05717.13 EHU02367.1 - 1.4e-39 134.1 0.0 1.6e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 IS66 Orf2 like protein DDE_Tnp_IS66 PF03050.14 EHU02368.1 - 1.1e-97 326.9 4.5 3.8e-97 325.1 0.0 2.1 2 0 0 2 2 2 1 Transposase IS66 family DDE_Tnp_IS66_C PF13817.6 EHU02368.1 - 3.2e-16 59.3 0.1 1.3e-15 57.3 0.1 2.2 1 0 0 1 1 1 1 IS66 C-terminal element zf-IS66 PF13005.7 EHU02368.1 - 1.5e-14 54.1 1.5 3.4e-14 52.9 1.5 1.7 1 0 0 1 1 1 1 zinc-finger binding domain of transposase IS66 LZ_Tnp_IS66 PF13007.7 EHU02368.1 - 8.7e-11 42.4 9.0 1.9e-10 41.4 9.0 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Phage_HK97_TLTM PF06120.11 EHU02368.1 - 0.011 15.0 0.8 0.021 14.0 0.8 1.4 1 0 0 1 1 1 0 Tail length tape measure protein Csm1_N PF18504.1 EHU02368.1 - 0.02 15.2 4.2 0.084 13.2 0.4 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain UME PF08064.13 EHU02368.1 - 0.033 14.1 0.3 20 5.1 0.0 3.1 2 1 1 3 3 3 0 UME (NUC010) domain Exonuc_VII_L PF02601.15 EHU02368.1 - 0.039 13.5 2.7 0.04 13.5 1.0 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Troponin PF00992.20 EHU02368.1 - 0.044 14.1 2.8 0.078 13.3 2.8 1.3 1 0 0 1 1 1 0 Troponin FUSC PF04632.12 EHU02368.1 - 0.048 12.2 7.4 0.077 11.5 7.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tho2 PF11262.8 EHU02368.1 - 0.049 12.8 0.6 0.081 12.1 0.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FAM184 PF15665.5 EHU02368.1 - 0.052 13.3 8.0 0.082 12.7 8.0 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B HalX PF08663.10 EHU02368.1 - 0.13 12.6 2.4 0.34 11.3 2.4 1.7 1 0 0 1 1 1 0 HalX domain LXG PF04740.12 EHU02368.1 - 0.14 11.8 2.8 0.35 10.5 0.4 2.1 1 1 1 2 2 2 0 LXG domain of WXG superfamily ERM PF00769.19 EHU02368.1 - 0.19 11.5 11.1 0.31 10.8 11.1 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DHR10 PF18595.1 EHU02368.1 - 0.38 10.8 10.9 0.66 10.0 10.9 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Zn-ribbon_8 PF09723.10 EHU02368.1 - 0.45 10.7 2.0 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF1192 PF06698.11 EHU02368.1 - 0.54 10.4 5.3 3.4 7.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMPIT PF07851.13 EHU02368.1 - 0.82 8.9 3.0 1.2 8.3 3.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAUS-augmin3 PF14932.6 EHU02368.1 - 2 8.0 8.1 4.3 6.8 8.1 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 OmpH PF03938.14 EHU02368.1 - 4.2 7.7 8.6 8.7 6.7 8.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CREPT PF16566.5 EHU02368.1 - 5.9 7.1 8.7 2.7 8.1 5.6 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour SlyX PF04102.12 EHU02368.1 - 9.3 7.0 9.0 18 6.1 2.3 3.0 1 1 1 2 2 2 0 SlyX AdoMet_dc PF02675.15 EHU02369.1 - 3.9e-30 104.2 0.0 8.3e-30 103.2 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine decarboxylase Spermine_synth PF01564.17 EHU02370.1 - 1.1e-65 220.6 0.0 1.5e-65 220.1 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 EHU02370.1 - 7e-19 67.5 0.1 1.1e-18 66.8 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 EHU02370.1 - 0.0001 22.9 0.0 0.0002 22.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EHU02370.1 - 0.0081 15.7 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EHU02370.1 - 0.023 15.4 0.0 0.047 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EHU02370.1 - 0.075 12.8 0.0 0.14 12.0 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain T2SS_PulS_OutS PF09691.10 EHU02371.1 - 2.1e-11 43.9 0.1 2.5e-11 43.7 0.1 1.1 1 0 0 1 1 1 1 Type II secretion system pilotin lipoprotein (PulS_OutS) DDE_3 PF13358.6 EHU02372.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 EHU02372.1 - 7.7e-09 36.1 0.3 2.3e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.6 EHU02372.1 - 1.7e-08 34.0 0.7 8.5e-07 28.6 0.0 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 EHU02372.1 - 3.6e-06 26.5 0.3 3.6e-06 26.5 0.3 3.0 4 0 0 4 4 4 1 Winged helix-turn helix HTH_29 PF13551.6 EHU02372.1 - 4.2e-06 26.7 0.4 1.9e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EHU02372.1 - 0.0013 18.8 0.2 0.022 14.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EHU02372.1 - 0.087 12.6 0.2 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EHU02372.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 Pribosyltran PF00156.27 EHU02373.1 - 9.8e-26 90.2 0.1 1.2e-25 89.9 0.1 1.0 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EHU02373.1 - 0.015 14.7 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Pro_CA PF00484.19 EHU02374.1 - 1.7e-50 171.4 0.0 2.1e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase ABC_tran PF00005.27 EHU02375.1 - 4.7e-32 111.4 0.0 8.8e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EHU02375.1 - 1.8e-12 47.7 1.8 1.2e-07 31.9 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EHU02375.1 - 5.9e-05 22.9 0.0 0.046 13.4 0.1 2.1 1 1 1 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 EHU02375.1 - 0.001 18.5 0.2 0.029 13.8 0.2 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EHU02375.1 - 0.0068 16.1 0.1 0.015 15.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF4162 PF13732.6 EHU02375.1 - 0.0081 16.9 0.1 0.025 15.3 0.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4162) AAA_30 PF13604.6 EHU02375.1 - 0.0092 15.7 0.1 0.026 14.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.22 EHU02375.1 - 0.021 14.5 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_27 PF13514.6 EHU02375.1 - 0.024 14.2 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EHU02375.1 - 0.035 14.6 0.3 0.071 13.6 0.3 1.6 1 1 0 1 1 1 0 AAA domain Mei4 PF13971.6 EHU02375.1 - 0.13 11.7 0.5 2.9 7.3 0.0 2.4 1 1 0 2 2 2 0 Meiosis-specific protein Mei4 DUF87 PF01935.17 EHU02375.1 - 0.16 12.0 0.9 1.9 8.5 1.0 2.3 1 1 0 1 1 1 0 Helicase HerA, central domain ABC2_membrane PF01061.24 EHU02376.1 - 9.5e-39 133.0 25.0 9.5e-39 133.0 25.0 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 EHU02376.1 - 2.6e-05 23.5 28.9 2.6e-05 23.5 28.9 1.5 1 1 1 2 2 2 1 ABC-2 family transporter protein CcmB PF03379.13 EHU02376.1 - 0.061 12.8 11.4 0.008 15.7 7.2 1.7 2 0 0 2 2 2 0 CcmB protein CoxIIa PF08113.11 EHU02376.1 - 0.31 10.9 9.1 0.61 9.9 3.1 3.1 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IIa family Orf78 PF06024.12 EHU02376.1 - 5.2 7.4 6.7 0.94 9.8 1.0 2.5 3 0 0 3 3 3 0 Orf78 (ac78) Asp_decarbox PF02261.16 EHU02377.1 - 5.9e-47 158.4 0.1 6.6e-47 158.2 0.1 1.0 1 0 0 1 1 1 1 Aspartate decarboxylase Pantoate_ligase PF02569.15 EHU02378.1 - 2e-102 342.0 0.0 2.2e-102 341.8 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase CTP_transf_like PF01467.26 EHU02378.1 - 0.033 14.4 0.0 0.061 13.5 0.0 1.6 1 0 0 1 1 1 0 Cytidylyltransferase-like Mannitol_dh PF01232.23 EHU02378.1 - 0.14 12.4 0.0 5.4 7.2 0.0 2.1 2 0 0 2 2 2 0 Mannitol dehydrogenase Rossmann domain Pantoate_transf PF02548.15 EHU02379.1 - 8.9e-107 356.3 0.6 1e-106 356.1 0.6 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase Asp_Glu_race PF01177.22 EHU02379.1 - 0.0018 18.2 0.0 0.0033 17.3 0.0 1.4 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Cu-oxidase_4 PF02578.15 EHU02379.1 - 0.05 13.2 0.1 0.061 12.9 0.1 1.3 1 0 0 1 1 1 0 Multi-copper polyphenol oxidoreductase laccase PEP_mutase PF13714.6 EHU02379.1 - 0.13 11.7 0.1 0.13 11.7 0.1 2.0 3 0 0 3 3 3 0 Phosphoenolpyruvate phosphomutase HPPK PF01288.20 EHU02380.1 - 3.1e-37 127.5 0.0 3.7e-37 127.3 0.0 1.0 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) PolyA_pol_arg_C PF12626.7 EHU02381.1 - 7.1e-40 135.8 1.2 7.1e-40 135.8 1.2 1.7 2 0 0 2 2 2 1 Polymerase A arginine-rich C-terminus PolyA_pol PF01743.20 EHU02381.1 - 8.1e-40 136.2 0.1 1.8e-39 135.0 0.1 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EHU02381.1 - 5.8e-19 67.6 0.2 2.2e-18 65.7 0.1 2.2 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A tRNA-synt_1c PF00749.21 EHU02382.1 - 5.3e-44 150.4 0.0 1.6e-42 145.6 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain zf-dskA_traR PF01258.17 EHU02383.1 - 2.3e-10 40.2 2.1 3.9e-10 39.5 2.1 1.3 1 0 0 1 1 1 1 Prokaryotic dksA/traR C4-type zinc finger DZR PF12773.7 EHU02383.1 - 0.044 13.8 0.2 0.078 13.0 0.2 1.3 1 0 0 1 1 1 0 Double zinc ribbon SfsA PF03749.13 EHU02384.1 - 2e-48 163.8 0.0 2.4e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 Sugar fermentation stimulation protein RE domain SfsA_N PF17746.1 EHU02384.1 - 7.5e-21 74.1 0.0 1.3e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 SfsA N-terminal OB domain DUF3883 PF13020.6 EHU02384.1 - 0.2 11.7 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3883) LigT_PEase PF02834.16 EHU02385.1 - 1.3e-22 79.8 2.7 1.8e-13 50.5 0.1 2.7 2 1 0 2 2 2 2 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.6 EHU02385.1 - 5.2e-13 49.2 0.8 5.8e-13 49.0 0.8 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily HrpB_C PF08482.10 EHU02386.1 - 7.1e-54 181.8 0.7 1.4e-53 180.8 0.7 1.6 1 0 0 1 1 1 1 ATP-dependent helicase C-terminal Helicase_C PF00271.31 EHU02386.1 - 1.4e-10 41.5 0.0 2.5e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EHU02386.1 - 1.4e-10 41.2 0.0 2.8e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HA2 PF04408.23 EHU02386.1 - 1.4e-07 31.7 0.0 3.5e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) AAA_22 PF13401.6 EHU02386.1 - 0.0029 17.9 0.5 0.011 16.0 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EHU02386.1 - 0.019 15.3 0.0 0.098 13.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EHU02386.1 - 0.036 13.8 0.3 0.3 10.8 0.0 2.6 4 0 0 4 4 4 0 AAA domain T2SSE PF00437.20 EHU02386.1 - 0.059 12.4 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Transgly PF00912.22 EHU02387.1 - 1e-55 188.0 0.0 2e-55 187.0 0.0 1.4 1 0 0 1 1 1 1 Transglycosylase UB2H PF14814.6 EHU02387.1 - 8.7e-28 96.2 0.0 2.9e-27 94.5 0.0 1.9 1 0 0 1 1 1 1 Bifunctional transglycosylase second domain PBP1_TM PF14812.6 EHU02387.1 - 1.1e-26 93.0 1.1 1.1e-26 93.0 1.1 2.2 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Transpeptidase PF00905.22 EHU02387.1 - 1.1e-25 90.5 0.1 1.1e-25 90.5 0.1 2.4 2 1 0 2 2 2 1 Penicillin binding protein transpeptidase domain UvrB_inter PF17757.1 EHU02387.1 - 2.4e-08 34.0 0.0 5.9e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 UvrB interaction domain DUF3484 PF11983.8 EHU02387.1 - 0.031 15.4 7.2 0.16 13.1 4.7 3.0 3 0 0 3 3 3 0 Membrane-attachment and polymerisation-promoting switch TFIIA PF03153.13 EHU02387.1 - 0.46 10.4 13.4 0.79 9.6 13.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DivIC PF04977.15 EHU02387.1 - 2.5 7.9 9.5 7.1 6.5 9.5 1.7 1 0 0 1 1 1 0 Septum formation initiator Spt20 PF12090.8 EHU02387.1 - 9.4 5.8 23.4 15 5.1 23.4 1.2 1 0 0 1 1 1 0 Spt20 family TonB_dep_Rec PF00593.24 EHU02388.1 - 2e-59 202.7 33.9 2e-59 202.7 33.9 1.9 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 EHU02388.1 - 3.8e-23 82.1 0.1 1.1e-22 80.6 0.1 1.9 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain ABC_tran PF00005.27 EHU02389.1 - 2.4e-32 112.3 0.0 3.1e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EHU02389.1 - 6.2e-09 35.6 0.0 4.5e-07 29.5 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EHU02389.1 - 4.4e-06 26.7 0.0 0.00069 19.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EHU02389.1 - 0.00011 22.7 0.1 0.00016 22.1 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EHU02389.1 - 0.00012 21.7 0.1 0.00025 20.7 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EHU02389.1 - 0.00053 19.8 0.0 0.00073 19.3 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EHU02389.1 - 0.00098 19.4 0.1 0.0028 17.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EHU02389.1 - 0.0015 19.1 0.1 0.0024 18.4 0.1 1.2 1 0 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 EHU02389.1 - 0.0022 16.9 0.4 0.67 8.7 0.1 2.2 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_30 PF13604.6 EHU02389.1 - 0.0033 17.2 0.4 0.0046 16.7 0.4 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EHU02389.1 - 0.006 16.7 0.1 0.01 16.0 0.1 1.6 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EHU02389.1 - 0.0072 16.2 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase cobW PF02492.19 EHU02389.1 - 0.0087 15.7 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 EHU02389.1 - 0.02 14.5 1.8 0.038 13.6 1.3 1.9 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EHU02389.1 - 0.085 12.8 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 EHU02389.1 - 0.093 13.3 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 EHU02389.1 - 0.099 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain TniB PF05621.11 EHU02389.1 - 0.1 12.0 0.0 2.5 7.5 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein AAA_28 PF13521.6 EHU02389.1 - 0.12 12.6 0.1 0.19 12.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EHU02389.1 - 0.16 12.0 0.0 0.63 10.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain Peripla_BP_2 PF01497.18 EHU02390.1 - 3.6e-31 108.6 0.0 4.3e-31 108.3 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein FecCD PF01032.18 EHU02391.1 - 7.4e-137 455.5 75.8 5.1e-69 232.7 35.2 2.0 2 0 0 2 2 2 2 FecCD transport family Aminotran_3 PF00202.21 EHU02392.1 - 4.1e-78 262.8 0.0 4.7e-78 262.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EHU02392.1 - 1.8e-06 27.4 0.0 3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1949 PF09186.11 EHU02392.1 - 0.1 12.5 0.0 0.75 9.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1949) Fe-S_biosyn PF01521.20 EHU02393.1 - 3.7e-21 75.4 0.0 4.1e-21 75.3 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis HCV_NS4a PF01006.20 EHU02394.1 - 0.049 13.4 0.0 0.057 13.2 0.0 1.2 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a Peripla_BP_2 PF01497.18 EHU02395.1 - 2.8e-21 76.2 0.0 3.5e-21 75.9 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein YAcAr PF10686.9 EHU02395.1 - 0.0084 16.0 0.0 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 YspA, cpYpsA-related SLOG family PNP_UDP_1 PF01048.20 EHU02396.1 - 1.5e-47 161.9 2.3 1.7e-47 161.7 2.3 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily HD PF01966.22 EHU02397.1 - 2.5e-10 40.6 0.0 8.3e-10 38.9 0.0 2.0 2 0 0 2 2 2 1 HD domain HD_assoc PF13286.6 EHU02397.1 - 3.8e-10 40.1 3.7 6.9e-05 23.3 0.3 3.5 2 1 1 3 3 3 2 Phosphohydrolase-associated domain DUF2267 PF10025.9 EHU02397.1 - 0.051 13.8 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) DUF3368 PF11848.8 EHU02397.1 - 0.12 12.2 0.0 16 5.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3368) Trypsin_2 PF13365.6 EHU02398.1 - 1.2e-32 113.8 0.6 2.3e-32 113.0 0.6 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ PF00595.24 EHU02398.1 - 1.1e-26 92.9 5.4 2.1e-12 47.2 0.1 3.4 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 EHU02398.1 - 7.9e-22 77.4 3.5 5.5e-13 49.1 0.1 2.8 3 0 0 3 3 3 2 PDZ domain Trypsin PF00089.26 EHU02398.1 - 1.5e-19 70.7 0.3 2.6e-19 69.9 0.3 1.4 1 0 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 EHU02398.1 - 9.8e-19 67.0 3.9 1.8e-09 37.3 0.4 3.0 3 0 0 3 3 3 2 PDZ domain Tricorn_PDZ PF14685.6 EHU02398.1 - 0.0022 17.9 0.8 4.1 7.5 0.1 3.4 3 0 0 3 3 3 2 Tricorn protease PDZ domain PDZ_1 PF12812.7 EHU02398.1 - 0.016 15.2 0.0 2.7 8.1 0.0 2.8 2 0 0 2 2 2 0 PDZ-like domain DUF2274 PF10038.9 EHU02398.1 - 0.021 15.3 0.0 0.15 12.5 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2274) Peptidase_S46 PF10459.9 EHU02398.1 - 0.036 12.7 0.6 0.31 9.6 0.5 2.0 2 0 0 2 2 2 0 Peptidase S46 DUF3394 PF11874.8 EHU02398.1 - 0.067 12.9 0.1 0.14 11.8 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3394) Tudor_2 PF18104.1 EHU02398.1 - 0.092 12.4 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain Diacid_rec PF05651.13 EHU02399.1 - 6.5e-48 161.8 0.1 9.7e-48 161.2 0.1 1.3 1 0 0 1 1 1 1 Putative sugar diacid recognition HTH_30 PF13556.6 EHU02399.1 - 4.3e-21 74.5 2.2 2.5e-20 72.0 0.4 2.7 3 0 0 3 3 3 1 PucR C-terminal helix-turn-helix domain GGDEF_2 PF17853.1 EHU02399.1 - 7.3e-19 68.1 0.3 1.5e-18 67.1 0.3 1.6 1 0 0 1 1 1 1 GGDEF-like domain Alginate_lyase PF05426.12 EHU02400.1 - 3.6e-84 282.5 1.5 5e-84 282.1 1.5 1.2 1 0 0 1 1 1 1 Alginate lyase DUF3461 PF11944.8 EHU02401.1 - 8.6e-55 184.2 2.2 9.6e-55 184.1 2.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3461) THDPS_N_2 PF14805.6 EHU02402.1 - 8e-26 90.1 0.3 1.3e-25 89.4 0.3 1.3 1 0 0 1 1 1 1 Tetrahydrodipicolinate N-succinyltransferase N-terminal Hexapep_2 PF14602.6 EHU02402.1 - 3.3e-13 49.1 1.6 3.3e-13 49.1 1.6 2.7 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 EHU02402.1 - 1.1e-12 47.1 9.4 4.8e-07 29.3 0.9 3.4 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) GlnD_UR_UTase PF08335.11 EHU02403.1 - 7.6e-35 120.2 1.7 2.8e-34 118.3 0.2 2.6 2 1 0 2 2 2 1 GlnD PII-uridylyltransferase ACT PF01842.25 EHU02403.1 - 1.9e-19 69.1 0.1 1.9e-08 33.9 0.0 2.6 2 0 0 2 2 2 2 ACT domain HD PF01966.22 EHU02403.1 - 9e-17 61.4 0.1 2.3e-16 60.1 0.1 1.8 1 0 0 1 1 1 1 HD domain NTP_transf_2 PF01909.23 EHU02403.1 - 4.2e-07 30.2 0.0 1.2e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF294 PF03445.13 EHU02403.1 - 0.00018 21.4 0.0 0.00054 19.8 0.0 1.8 1 0 0 1 1 1 1 Putative nucleotidyltransferase DUF294 ACT_4 PF13291.6 EHU02403.1 - 0.034 14.7 0.0 0.77 10.4 0.0 2.4 2 0 0 2 2 2 0 ACT domain Polbeta PF18765.1 EHU02403.1 - 0.065 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Peptidase_M24 PF00557.24 EHU02404.1 - 3.2e-53 180.5 0.2 3.6e-53 180.4 0.2 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 Ribosomal_S2 PF00318.20 EHU02405.1 - 2.4e-93 311.3 0.0 2.7e-93 311.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S2 TBK1_ULD PF18396.1 EHU02405.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain EF_TS PF00889.19 EHU02406.1 - 2e-65 220.3 3.9 2e-65 220.3 3.9 1.5 2 0 0 2 2 2 1 Elongation factor TS AA_kinase PF00696.28 EHU02407.1 - 4e-27 95.3 0.3 4.8e-27 95.1 0.3 1.1 1 0 0 1 1 1 1 Amino acid kinase family RRF PF01765.19 EHU02408.1 - 1.1e-62 210.8 0.7 1.5e-62 210.3 0.7 1.2 1 0 0 1 1 1 1 Ribosome recycling factor DXP_reductoisom PF02670.16 EHU02409.1 - 4.9e-47 159.8 3.4 9.6e-47 158.9 3.4 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXPR_C PF13288.6 EHU02409.1 - 5.3e-41 139.5 1.7 5.4e-41 139.5 0.1 1.8 2 0 0 2 2 2 1 DXP reductoisomerase C-terminal domain DXP_redisom_C PF08436.12 EHU02409.1 - 4.1e-37 126.2 0.0 8.9e-37 125.1 0.0 1.6 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain Prenyltransf PF01255.19 EHU02410.1 - 2.9e-77 259.2 0.1 3.4e-77 259.0 0.1 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase CTP_transf_1 PF01148.20 EHU02411.1 - 4.8e-70 236.4 16.9 5.7e-70 236.1 16.9 1.0 1 0 0 1 1 1 1 Cytidylyltransferase family CarS-like PF01864.17 EHU02411.1 - 0.017 15.1 0.2 0.017 15.1 0.2 2.0 3 0 0 3 3 3 0 CDP-archaeol synthase Peptidase_M50 PF02163.22 EHU02412.1 - 8.9e-86 287.2 0.2 1.1e-85 286.9 0.2 1.0 1 0 0 1 1 1 1 Peptidase family M50 PDZ_6 PF17820.1 EHU02412.1 - 7.2e-14 51.4 1.4 1.2e-10 41.0 0.1 2.7 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EHU02412.1 - 4.9e-13 49.2 0.2 5.4e-10 39.5 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 EHU02412.1 - 4.1e-10 39.9 0.2 5.3e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 EHU02412.1 - 1e-05 25.4 0.3 0.021 14.7 0.1 2.7 2 0 0 2 2 2 2 Tricorn protease PDZ domain GRASP55_65 PF04495.14 EHU02412.1 - 0.0024 18.2 0.0 0.0047 17.3 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain Peptidase_M50B PF13398.6 EHU02412.1 - 0.028 14.1 0.4 0.028 14.1 0.4 2.4 3 0 0 3 3 3 0 Peptidase M50B-like Bac_surface_Ag PF01103.23 EHU02413.1 - 7.9e-101 337.8 16.1 1.6e-100 336.7 16.1 1.5 1 0 0 1 1 1 1 Surface antigen POTRA PF07244.15 EHU02413.1 - 1e-60 202.3 10.5 5.5e-15 55.7 0.1 5.3 5 0 0 5 5 5 5 Surface antigen variable number repeat POTRA_2 PF08479.11 EHU02413.1 - 2.1e-06 27.4 0.7 0.73 9.7 0.0 5.1 4 1 0 4 4 4 2 POTRA domain, ShlB-type POTRA_1 PF08478.10 EHU02413.1 - 1.2e-05 25.5 0.8 0.15 12.4 0.0 4.6 5 0 0 5 5 5 2 POTRA domain, FtsQ-type BatD PF13584.6 EHU02413.1 - 0.033 13.0 0.0 0.061 12.1 0.0 1.4 1 0 0 1 1 1 0 Oxygen tolerance DAO_C PF16901.5 EHU02413.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 C-terminal domain of alpha-glycerophosphate oxidase YqfD PF06898.11 EHU02413.1 - 0.22 10.3 0.7 0.65 8.8 0.0 2.0 2 1 1 3 3 3 0 Putative stage IV sporulation protein YqfD OmpH PF03938.14 EHU02414.1 - 1.4e-30 106.5 17.9 1.6e-30 106.3 17.9 1.0 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) TrbI_Ftype PF09677.10 EHU02414.1 - 0.0027 18.0 12.8 0.034 14.5 2.0 2.6 1 1 2 3 3 3 2 Type-F conjugative transfer system protein (TrbI_Ftype) DUF3552 PF12072.8 EHU02414.1 - 0.0033 16.8 10.2 0.0041 16.6 10.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) PIN_8 PF18476.1 EHU02414.1 - 0.097 12.5 7.9 0.12 12.2 7.9 1.2 1 0 0 1 1 1 0 PIN like domain TMPIT PF07851.13 EHU02414.1 - 1.8 7.8 7.5 2.1 7.5 7.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein T3SSipB PF16535.5 EHU02414.1 - 2 8.9 17.7 2.4 8.6 17.3 1.3 1 1 0 1 1 1 0 Type III cell invasion protein SipB YnfE PF17452.2 EHU02414.1 - 4.4 7.7 8.4 4.9 7.5 3.5 2.9 2 1 2 4 4 4 0 Uncharacterized YnfE-like Hexapep PF00132.24 EHU02415.1 - 6.4e-31 104.9 32.6 1.4e-09 37.3 0.9 5.6 4 1 2 6 6 6 6 Bacterial transferase hexapeptide (six repeats) LpxD PF04613.14 EHU02415.1 - 8.6e-22 76.7 0.1 1.4e-21 76.0 0.1 1.3 1 0 0 1 1 1 1 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD Hexapep_2 PF14602.6 EHU02415.1 - 4.2e-11 42.4 36.2 1.8e-07 30.8 4.2 5.6 4 1 0 4 4 4 3 Hexapeptide repeat of succinyl-transferase GTP_EFTU_D2 PF03144.25 EHU02415.1 - 0.074 13.4 1.1 0.61 10.5 0.1 2.8 3 0 0 3 3 3 0 Elongation factor Tu domain 2 FabA PF07977.13 EHU02416.1 - 1e-40 138.5 0.0 1.2e-40 138.3 0.0 1.0 1 0 0 1 1 1 1 FabA-like domain 4HBT PF03061.22 EHU02416.1 - 0.019 15.3 0.0 0.033 14.5 0.0 1.5 1 1 0 1 1 1 0 Thioesterase superfamily MaoC_dehydratas PF01575.19 EHU02416.1 - 0.02 14.4 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 MaoC like domain PS-DH PF14765.6 EHU02416.1 - 0.04 13.1 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Polyketide synthase dehydratase Acetyltransf_11 PF13720.6 EHU02417.1 - 3.4e-29 101.1 0.0 5.2e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Hexapep PF00132.24 EHU02417.1 - 7.6e-26 88.8 26.1 3.9e-08 32.7 5.1 6.2 3 3 2 5 5 5 5 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 EHU02417.1 - 0.0012 17.9 0.6 0.094 11.6 0.0 2.1 1 1 1 2 2 2 2 L-fucokinase Hexapep_2 PF14602.6 EHU02417.1 - 0.028 14.2 1.6 0.028 14.2 1.6 5.1 4 2 1 5 5 5 0 Hexapeptide repeat of succinyl-transferase LpxB PF02684.15 EHU02418.1 - 6.6e-145 482.7 0.0 7.4e-145 482.5 0.0 1.0 1 0 0 1 1 1 1 Lipid-A-disaccharide synthetase RNase_HII PF01351.18 EHU02419.1 - 1.9e-38 132.3 0.0 2.2e-38 132.1 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease HII DNA_pol3_alpha PF07733.12 EHU02420.1 - 9.7e-105 349.8 0.0 2.1e-104 348.7 0.0 1.6 2 0 0 2 2 2 1 Bacterial DNA polymerase III alpha NTPase domain DNA_pol3_finger PF17657.1 EHU02420.1 - 5.6e-66 221.0 0.1 9.9e-66 220.2 0.1 1.4 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha subunit finger domain PHP PF02811.19 EHU02420.1 - 5.3e-43 147.2 0.0 2.8e-42 144.9 0.0 2.1 2 0 0 2 2 2 1 PHP domain HHH_6 PF14579.6 EHU02420.1 - 3.2e-25 88.2 0.0 8.3e-25 86.9 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif tRNA_anti-codon PF01336.25 EHU02420.1 - 8.7e-09 35.2 0.1 2.1e-08 34.1 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain ACCA PF03255.14 EHU02421.1 - 3.7e-62 208.5 0.1 5.9e-62 207.8 0.1 1.3 1 0 0 1 1 1 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Carboxyl_trans PF01039.22 EHU02421.1 - 2.1e-18 66.2 0.1 2.9e-18 65.8 0.1 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 EHU02421.1 - 0.0012 18.4 0.0 0.0018 17.8 0.0 1.2 1 0 0 1 1 1 1 Malonate decarboxylase gamma subunit (MdcE) OKR_DC_1 PF01276.20 EHU02422.1 - 2.9e-186 619.3 0.0 3.5e-186 619.0 0.0 1.1 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain OKR_DC_1_C PF03711.15 EHU02422.1 - 1.3e-45 154.9 0.1 2.4e-45 154.1 0.1 1.5 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, C-terminal domain OKR_DC_1_N PF03709.15 EHU02422.1 - 1.6e-25 89.5 0.0 3.5e-25 88.4 0.0 1.6 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, N-terminal domain Glyoxalase PF00903.25 EHU02423.1 - 2.8e-18 66.3 0.0 3.2e-18 66.2 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EHU02423.1 - 1.8e-11 44.3 0.0 2e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EHU02423.1 - 4.2e-06 27.0 0.0 5.2e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 EHU02423.1 - 4.4e-06 27.4 0.0 5.6e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 EHU02423.1 - 0.026 14.5 0.0 0.039 13.9 0.0 1.3 1 1 0 1 1 1 0 Glyoxalase-like domain ATP_bind_3 PF01171.20 EHU02424.1 - 6e-60 202.1 0.1 9e-60 201.5 0.1 1.3 1 0 0 1 1 1 1 PP-loop family TilS_C PF11734.8 EHU02424.1 - 1.1e-22 79.2 0.1 2.6e-22 78.0 0.1 1.7 1 0 0 1 1 1 1 TilS substrate C-terminal domain TilS PF09179.11 EHU02424.1 - 1.2e-18 67.4 7.0 1.2e-18 67.4 7.0 4.0 3 0 0 3 3 3 1 TilS substrate binding domain QueC PF06508.13 EHU02424.1 - 0.12 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Cytochrome_CBB3 PF13442.6 EHU02425.1 - 5.5e-09 36.2 0.3 7.3e-09 35.8 0.3 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 EHU02425.1 - 5.1e-08 34.0 0.4 1e-07 33.0 0.4 1.5 1 1 0 1 1 1 1 Cytochrome c ROF PF07073.12 EHU02426.1 - 1.7e-26 92.2 0.0 1.8e-26 92.1 0.0 1.0 1 0 0 1 1 1 1 Modulator of Rho-dependent transcription termination (ROF) UPF0253 PF06786.12 EHU02427.1 - 4.9e-34 116.4 4.2 5.4e-34 116.3 4.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0253) RF-1 PF00472.20 EHU02428.1 - 2.1e-25 88.9 0.9 2.6e-25 88.6 0.9 1.0 1 0 0 1 1 1 1 RF-1 domain tRNA-synt_2b PF00587.25 EHU02429.1 - 4.8e-51 173.3 0.0 7.4e-51 172.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.15 EHU02429.1 - 1e-24 87.0 0.1 2.1e-24 85.9 0.1 1.6 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain HGTP_anticodon PF03129.20 EHU02429.1 - 3.1e-20 72.1 0.4 6.7e-20 71.0 0.4 1.6 1 0 0 1 1 1 1 Anticodon binding domain TrmO PF01980.16 EHU02430.1 - 1.4e-44 151.1 0.0 1.8e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 tRNA-methyltransferase O TrmO_C PF18389.1 EHU02430.1 - 1e-21 76.8 1.1 3.1e-21 75.2 0.3 1.9 2 0 0 2 2 2 1 TrmO C-terminal domain OSK PF17182.4 EHU02430.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 OSK domain RcsF PF16358.5 EHU02431.1 - 1e-48 163.9 0.6 1.3e-48 163.6 0.6 1.1 1 0 0 1 1 1 1 RcsF lipoprotein Adeno_E1A PF02703.14 EHU02431.1 - 0.01 15.5 1.0 0.012 15.2 1.0 1.1 1 0 0 1 1 1 0 Early E1A protein DUF5006 PF16397.5 EHU02431.1 - 0.028 13.6 0.1 0.045 12.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5006) DUF4156 PF13698.6 EHU02431.1 - 0.09 13.1 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4156) Lipoprotein_9 PF03180.14 EHU02432.1 - 3.1e-100 334.2 2.0 3.5e-100 334.0 2.0 1.0 1 0 0 1 1 1 1 NLPA lipoprotein OpuAC PF04069.12 EHU02432.1 - 3.3e-05 23.6 0.9 4.6e-05 23.1 0.8 1.6 1 1 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system Phosphonate-bd PF12974.7 EHU02432.1 - 0.0023 17.6 0.2 0.0061 16.2 0.0 1.7 2 0 0 2 2 2 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 EHU02432.1 - 0.01 15.8 0.1 0.17 11.8 0.0 2.1 2 0 0 2 2 2 1 NMT1/THI5 like BPD_transp_1 PF00528.22 EHU02433.1 - 3.1e-21 76.0 16.6 3.1e-21 76.0 16.6 1.3 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 EHU02434.1 - 7.9e-36 123.6 0.0 1.6e-35 122.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter NIL PF09383.10 EHU02434.1 - 1.4e-20 72.9 0.0 2.6e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 NIL domain AAA_21 PF13304.6 EHU02434.1 - 9.4e-09 35.5 0.5 0.00061 19.7 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EHU02434.1 - 7.9e-07 28.7 0.1 2.2e-06 27.3 0.1 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EHU02434.1 - 2.5e-05 24.6 0.4 0.00019 21.7 0.4 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EHU02434.1 - 0.0013 19.1 2.0 0.0043 17.5 2.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EHU02434.1 - 0.006 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 EHU02434.1 - 0.0064 16.1 0.2 3.8 7.1 0.0 2.9 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 EHU02434.1 - 0.015 15.2 0.1 0.032 14.2 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase SbcCD_C PF13558.6 EHU02434.1 - 0.029 14.6 0.1 0.23 11.7 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 EHU02434.1 - 0.036 13.8 0.1 0.094 12.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EHU02434.1 - 0.053 12.9 0.0 0.68 9.3 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein ABC_ATPase PF09818.9 EHU02434.1 - 0.12 11.2 0.2 3.2 6.4 0.0 2.3 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_23 PF13476.6 EHU02434.1 - 0.14 12.7 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain HAD_2 PF13419.6 EHU02435.1 - 7.5e-14 52.2 0.1 2.5e-07 31.0 0.1 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EHU02435.1 - 2.6e-13 49.8 0.0 4.2e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EHU02435.1 - 1e-09 39.0 0.1 5.4e-09 36.6 0.0 2.0 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase PNK3P PF08645.11 EHU02435.1 - 5.1e-09 36.0 0.0 7e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase Hydrolase_6 PF13344.6 EHU02435.1 - 9.8e-06 25.6 0.0 1.9e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 EHU02435.1 - 0.0049 17.3 0.3 0.013 15.9 0.0 1.8 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Glyco_trans_4_3 PF12000.8 EHU02435.1 - 0.016 14.9 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 4 group Hydrolase_3 PF08282.12 EHU02435.1 - 0.17 11.6 0.1 7.3 6.2 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Pantoea_stewartii_subsp._stewartii_DC283-ASM24839v2/GCA_000248395.2_ASM24839v2_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Pantoea_stewartii_subsp._stewartii_DC283-ASM24839v2/GCA_000248395.2_ASM24839v2_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Pantoea_stewartii_subsp._stewartii_DC283-ASM24839v2/GCA_000248395.2_ASM24839v2_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Pantoea_stewartii_subsp._stewartii_DC283-ASM24839v2/GCA_000248395.2_ASM24839v2_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 03:45:36 2019 # [ok]