# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- NHL PF01436.21 ABK69526.1 - 0.0041 17.1 2.9 7.4 6.8 0.0 4.2 5 0 0 5 5 5 2 NHL repeat TruB_C PF09142.11 ABK69526.1 - 0.083 12.7 0.4 0.083 12.7 0.4 2.8 3 0 0 3 3 3 0 tRNA Pseudouridine synthase II, C terminal Rieske_2 PF13806.6 ABK69527.1 - 1e-31 109.0 0.0 1.2e-31 108.8 0.0 1.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Ring_hydroxyl_A PF00848.19 ABK69528.1 - 2.2e-39 135.6 0.6 4.1e-39 134.8 0.6 1.4 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 ABK69528.1 - 3.5e-12 46.1 0.0 6.4e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain SBP_bac_3 PF00497.20 ABK69529.1 - 8.5e-50 169.3 0.0 1e-49 169.0 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 ABK69529.1 - 0.00015 21.9 0.0 0.00054 20.1 0.0 1.9 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site PfkB PF00294.24 ABK69530.1 - 9.5e-38 130.2 0.1 1.2e-37 129.9 0.1 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HTH_42 PF06224.12 ABK69531.1 - 5.2e-62 210.3 24.1 6.3e-62 210.0 24.1 1.1 1 0 0 1 1 1 1 Winged helix DNA-binding domain Ribosomal_S19e PF01090.19 ABK69531.1 - 0.005 16.6 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S19e CAP_N PF01213.19 ABK69532.1 - 0.52 9.7 4.4 0.57 9.6 4.4 1.0 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TetR_C_31 PF17940.1 ABK69533.1 - 0.14 12.3 0.2 1.3 9.3 0.0 2.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain NIPSNAP PF07978.13 ABK69534.1 - 4e-06 27.0 0.2 0.012 15.8 0.0 2.2 2 0 0 2 2 2 2 NIPSNAP adh_short_C2 PF13561.6 ABK69535.1 - 2.4e-53 181.1 2.4 1e-50 172.5 2.4 2.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK69535.1 - 1.9e-48 164.5 1.2 7.5e-46 156.1 1.2 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK69535.1 - 4.2e-09 36.6 0.3 6.5e-09 36.0 0.3 1.2 1 0 0 1 1 1 1 KR domain Pterin_bind PF00809.22 ABK69535.1 - 0.015 15.0 1.1 0.024 14.3 1.1 1.2 1 0 0 1 1 1 0 Pterin binding enzyme CbiQ PF02361.16 ABK69536.1 - 4.5e-20 72.2 10.7 4.5e-20 72.2 10.7 1.3 2 0 0 2 2 2 1 Cobalt transport protein NIR_SIR_ferr PF03460.17 ABK69537.1 - 1.4e-17 63.3 0.7 2.2e-11 43.4 0.1 2.8 2 1 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain AMP-binding PF00501.28 ABK69538.1 - 3.8e-101 338.7 0.1 4.8e-101 338.4 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK69538.1 - 2.3e-27 95.8 2.1 6.1e-27 94.4 0.7 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 ABK69538.1 - 3e-21 75.1 1.2 3e-21 75.1 1.2 1.9 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AA_permease_2 PF13520.6 ABK69539.1 - 4.1e-34 118.1 42.6 4.1e-34 118.1 42.6 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ABK69539.1 - 9e-19 67.4 37.2 1.5e-18 66.7 37.2 1.2 1 0 0 1 1 1 1 Amino acid permease DUF5455 PF17537.2 ABK69539.1 - 0.012 16.0 0.5 0.012 16.0 0.5 3.5 4 1 1 5 5 5 0 Family of unknown function (DUF5455) DUF2627 PF11118.8 ABK69539.1 - 4.1 8.1 9.5 30 5.3 1.3 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) DUF2334 PF10096.9 ABK69540.1 - 1.7e-18 67.1 0.0 1.9e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF1942 PF09167.11 ABK69541.1 - 3e-44 150.0 1.4 3.7e-44 149.7 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1942) DUF4352 PF11611.8 ABK69541.1 - 0.0019 18.4 0.2 0.003 17.8 0.2 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4352) Nucleoporin_FG2 PF15967.5 ABK69541.1 - 0.069 11.7 7.9 0.086 11.4 7.9 1.0 1 0 0 1 1 1 0 Nucleoporin FG repeated region UPF0126 PF03458.13 ABK69542.1 - 2.7e-39 132.9 30.2 1.6e-21 76.0 6.6 2.8 2 1 1 3 3 3 2 UPF0126 domain MFS_1 PF07690.16 ABK69543.1 - 4.5e-31 108.1 85.2 3.4e-30 105.1 47.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Arg_repressor PF01316.21 ABK69544.1 - 5e-25 87.0 0.0 7.3e-25 86.5 0.0 1.2 1 0 0 1 1 1 1 Arginine repressor, DNA binding domain Arg_repressor_C PF02863.18 ABK69544.1 - 7.2e-24 83.4 0.1 1.3e-23 82.7 0.1 1.4 1 0 0 1 1 1 1 Arginine repressor, C-terminal domain HTH_DeoR PF08220.12 ABK69544.1 - 0.065 13.0 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_20 PF12840.7 ABK69544.1 - 0.066 13.3 0.3 0.066 13.3 0.3 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_11 PF08279.12 ABK69544.1 - 0.072 13.0 0.3 10 6.2 0.2 2.9 2 1 0 2 2 2 0 HTH domain RNA_pol_Rpb6 PF01192.22 ABK69545.1 - 1.6e-13 50.4 0.0 2.6e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 zf-C2HC_2 PF13913.6 ABK69546.1 - 0.082 12.8 0.1 0.082 12.8 0.1 3.2 3 2 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 ABK69546.1 - 0.26 12.2 0.6 0.26 12.2 0.6 3.1 3 1 0 3 3 3 0 C2H2-type zinc finger DUF4439 PF14530.6 ABK69547.1 - 1.4e-43 148.7 4.9 1.6e-43 148.5 4.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4439) Ferritin_2 PF13668.6 ABK69547.1 - 0.066 13.4 1.0 0.085 13.1 1.0 1.1 1 0 0 1 1 1 0 Ferritin-like domain LEA_3 PF03242.13 ABK69547.1 - 0.34 11.6 0.1 0.34 11.6 0.1 2.9 1 1 2 3 3 3 0 Late embryogenesis abundant protein Exo_endo_phos PF03372.23 ABK69548.1 - 3.6e-15 56.1 0.0 4.9e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Mrr_cat PF04471.12 ABK69549.1 - 6.9e-23 80.9 0.0 8.5e-23 80.6 0.0 1.1 1 0 0 1 1 1 1 Restriction endonuclease Mrr_cat_2 PF13156.6 ABK69549.1 - 0.0029 17.5 0.0 0.0036 17.2 0.0 1.1 1 0 0 1 1 1 1 Restriction endonuclease Epimerase PF01370.21 ABK69550.1 - 5.6e-21 75.1 0.0 7e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ABK69550.1 - 2.2e-15 56.9 0.0 2.3e-14 53.5 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ABK69550.1 - 9.1e-11 41.3 0.0 1.2e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 ABK69550.1 - 0.0013 17.9 0.0 0.002 17.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 ABK69550.1 - 0.0021 17.3 0.1 0.049 12.8 0.0 2.4 1 1 1 2 2 2 1 Male sterility protein UPF0227 PF05728.12 ABK69550.1 - 0.042 13.8 0.0 0.07 13.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) ABC_membrane_2 PF06472.15 ABK69551.1 - 1.4e-69 234.5 0.1 2.1e-69 233.9 0.1 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 SbmA_BacA PF05992.12 ABK69551.1 - 3.2e-24 85.9 1.6 3.2e-24 85.9 1.6 2.1 2 1 0 2 2 1 1 SbmA/BacA-like family ABC_tran PF00005.27 ABK69551.1 - 1.4e-15 58.0 0.0 2.3e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 ABK69551.1 - 2.5e-07 31.2 0.3 7.3e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 ABK69551.1 - 0.00012 21.9 0.1 0.00031 20.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ABK69551.1 - 0.0023 18.2 0.1 0.0064 16.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 ABK69551.1 - 0.0031 17.4 0.2 0.0082 16.1 0.0 1.7 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.6 ABK69551.1 - 0.011 15.9 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 ABK69551.1 - 0.017 15.5 0.0 0.063 13.7 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 ABK69551.1 - 0.029 14.1 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 ABK69551.1 - 0.04 13.9 0.0 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 ABK69551.1 - 0.048 13.8 0.5 0.18 11.9 0.5 2.0 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ABK69551.1 - 0.055 14.0 0.0 0.094 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 ABK69551.1 - 0.061 13.7 0.0 0.28 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 ABK69551.1 - 0.063 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain T2SSE PF00437.20 ABK69551.1 - 0.071 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.6 ABK69551.1 - 0.085 12.4 0.2 0.28 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 ABK69551.1 - 0.12 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase SMC_N PF02463.19 ABK69551.1 - 0.13 11.7 0.0 3.4 7.1 0.0 2.1 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ABK69551.1 - 0.17 11.6 0.0 0.63 9.8 0.0 1.9 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 ABK69551.1 - 0.18 11.3 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Proton_antipo_M PF00361.20 ABK69552.1 - 1.8e-82 276.9 13.1 1.8e-82 276.9 13.1 1.9 2 0 0 2 2 2 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 ABK69552.1 - 1.8e-25 88.7 1.1 6.4e-25 87.0 0.0 2.6 2 0 0 2 2 2 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus NADH5_C PF06455.11 ABK69552.1 - 0.00023 20.8 0.2 0.0013 18.3 0.2 2.4 2 1 0 2 2 2 1 NADH dehydrogenase subunit 5 C-terminus Oxidored_q5_N PF01059.17 ABK69552.1 - 0.035 14.2 0.4 0.12 12.5 0.1 2.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus Proton_antipo_C PF01010.19 ABK69552.1 - 0.04 13.5 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus Lactamase_B PF00753.27 ABK69553.1 - 3.2e-29 102.4 4.9 3.7e-29 102.1 4.9 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ABK69553.1 - 1.2e-05 24.9 1.2 3.4e-05 23.4 1.2 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ABK69553.1 - 0.00012 22.1 0.0 0.00029 20.8 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain RPE65 PF03055.15 ABK69554.1 - 3.9e-104 349.4 0.0 4.5e-104 349.2 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Pyr_redox_2 PF07992.14 ABK69556.1 - 1.5e-46 159.0 0.0 1.8e-46 158.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ABK69556.1 - 1.4e-12 48.0 1.6 2.5e-06 28.0 0.3 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ABK69556.1 - 2.5e-05 24.0 7.5 0.0013 18.3 7.5 2.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ABK69556.1 - 3.6e-05 23.9 1.7 0.00018 21.6 0.6 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ABK69556.1 - 0.00042 19.2 0.2 0.003 16.3 0.0 2.3 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.22 ABK69556.1 - 0.0047 16.1 0.1 0.13 11.4 0.1 2.9 3 1 1 4 4 4 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 ABK69556.1 - 0.0075 15.6 0.1 0.0075 15.6 0.1 2.5 2 1 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 ABK69556.1 - 0.013 14.6 1.1 0.038 13.1 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 ABK69556.1 - 0.014 15.4 1.5 2 8.4 0.1 3.5 3 1 1 4 4 4 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 ABK69556.1 - 0.025 13.6 0.2 0.18 10.8 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 ABK69556.1 - 0.15 11.3 0.1 0.28 10.4 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glyoxalase PF00903.25 ABK69557.1 - 7e-07 29.5 0.2 9.6e-07 29.0 0.2 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 ABK69557.1 - 0.00057 19.8 0.0 0.0021 18.0 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 ABK69557.1 - 0.018 15.8 0.1 0.037 14.8 0.1 1.5 1 1 0 1 1 1 0 Glyoxalase-like domain TetR_N PF00440.23 ABK69558.1 - 3.5e-14 52.3 0.1 6.9e-14 51.4 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 ABK69558.1 - 2.8e-05 24.4 1.5 2.8e-05 24.4 1.5 3.0 1 1 2 3 3 3 2 Tetracyclin repressor-like, C-terminal domain DUF1204 PF06721.11 ABK69558.1 - 0.016 14.6 0.3 0.033 13.7 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1204) LacI PF00356.21 ABK69558.1 - 0.036 13.9 0.7 0.19 11.5 0.2 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family 2Fe-2S_thioredx PF01257.19 ABK69558.1 - 0.17 11.8 0.0 1.5 8.7 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin-like [2Fe-2S] ferredoxin ANTAR PF03861.14 ABK69558.1 - 0.51 10.2 5.3 2.3 8.1 0.0 3.4 3 1 0 3 3 3 0 ANTAR domain Aminotran_1_2 PF00155.21 ABK69560.1 - 1.8e-17 63.6 0.0 2.9e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 ABK69560.1 - 4e-16 58.4 0.1 9.7e-16 57.2 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_36 PF13730.6 ABK69560.1 - 0.002 18.1 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 ABK69560.1 - 0.0067 16.4 0.1 0.018 15.0 0.1 1.8 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_IclR PF09339.10 ABK69560.1 - 0.051 13.4 0.1 0.18 11.7 0.1 2.0 1 0 0 1 1 1 0 IclR helix-turn-helix domain Rrf2 PF02082.20 ABK69560.1 - 0.059 13.7 0.2 0.16 12.3 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator MarR PF01047.22 ABK69560.1 - 0.082 12.9 0.0 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 MarR family HTH_24 PF13412.6 ABK69560.1 - 0.093 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_50 PF18024.1 ABK69560.1 - 0.18 11.5 2.3 0.36 10.5 0.2 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Lum_binding PF00677.17 ABK69562.1 - 6.3e-48 160.7 1.1 6.1e-25 87.0 0.1 2.0 2 0 0 2 2 2 2 Lumazine binding domain Carboxyl_trans PF01039.22 ABK69563.1 - 2.3e-48 165.0 0.0 3e-48 164.7 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain ACCA PF03255.14 ABK69563.1 - 9.6e-08 32.0 0.0 2e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit MdcE PF06833.11 ABK69563.1 - 0.015 14.8 6.7 0.3 10.5 0.5 3.1 3 0 0 3 3 3 0 Malonate decarboxylase gamma subunit (MdcE) ECH_1 PF00378.20 ABK69563.1 - 0.032 13.5 4.7 0.17 11.2 0.1 3.2 3 1 0 3 3 3 0 Enoyl-CoA hydratase/isomerase Peptidase_M17 PF00883.21 ABK69564.1 - 2.7e-112 375.1 0.0 3.5e-112 374.7 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 ABK69564.1 - 1.4e-23 83.1 1.2 3.1e-23 82.0 0.1 2.1 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain ECH_1 PF00378.20 ABK69565.1 - 9e-51 172.6 0.0 1.2e-50 172.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK69565.1 - 4.2e-24 85.7 0.1 5e-24 85.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase NHase_beta PF02211.15 ABK69566.1 - 2.6e-08 34.2 0.4 8.4e-08 32.5 0.4 1.6 1 1 0 1 1 1 1 Nitrile hydratase beta subunit LysR_substrate PF03466.20 ABK69567.1 - 3.6e-41 140.8 9.2 3.6e-41 140.8 9.2 1.7 1 1 1 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 ABK69567.1 - 7.5e-16 57.8 4.7 7.5e-16 57.8 4.7 2.6 3 0 0 3 3 3 1 Bacterial regulatory helix-turn-helix protein, lysR family PBP_like PF12727.7 ABK69567.1 - 2.8e-06 26.6 0.1 7.7e-06 25.2 0.0 1.7 1 1 0 1 1 1 1 PBP superfamily domain MarR_2 PF12802.7 ABK69567.1 - 8.5e-05 22.4 0.9 0.00038 20.3 0.9 2.2 1 0 0 1 1 1 1 MarR family PBP_like_2 PF12849.7 ABK69567.1 - 0.005 16.6 0.1 0.031 13.9 0.1 2.0 1 1 0 1 1 1 1 PBP superfamily domain HTH_30 PF13556.6 ABK69567.1 - 0.05 13.4 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.6 ABK69567.1 - 0.053 13.6 0.2 0.17 12.0 0.2 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain rve PF00665.26 ABK69568.1 - 5.9e-26 91.0 0.0 8.9e-26 90.4 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 ABK69568.1 - 7e-07 28.9 0.0 3.8e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain rve_2 PF13333.6 ABK69568.1 - 0.00063 19.9 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain NMT1 PF09084.11 ABK69569.1 - 4e-24 85.8 0.0 6.2e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 ABK69569.1 - 3.3e-12 46.6 0.1 1.1e-11 44.9 0.1 1.8 1 1 0 1 1 1 1 NMT1-like family VitK2_biosynth PF02621.14 ABK69569.1 - 0.0079 15.7 0.1 0.056 13.0 0.1 2.0 1 1 0 1 1 1 1 Menaquinone biosynthesis GAF_2 PF13185.6 ABK69570.1 - 0.0024 18.2 0.3 0.0041 17.4 0.3 1.5 1 1 0 1 1 1 1 GAF domain Carboxyl_trans PF01039.22 ABK69571.1 - 1.1e-150 502.5 0.0 1.4e-150 502.2 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 ABK69571.1 - 4.1e-05 23.2 0.5 0.061 12.8 0.1 2.4 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) NMT1 PF09084.11 ABK69573.1 - 5.6e-27 95.1 0.0 7.9e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 ABK69573.1 - 1.2e-16 61.1 0.2 2.3e-16 60.2 0.2 1.4 1 1 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 ABK69573.1 - 2e-09 37.4 1.2 3.2e-09 36.8 1.0 1.5 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 ABK69573.1 - 2.2e-09 37.1 0.1 4.4e-09 36.1 0.1 1.6 1 1 1 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_3 PF16868.5 ABK69573.1 - 9.1e-08 31.9 0.1 2e-07 30.8 0.1 1.5 1 1 0 1 1 1 1 NMT1-like family OpuAC PF04069.12 ABK69573.1 - 0.00015 21.4 5.1 0.0012 18.5 5.1 2.6 1 1 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system VitK2_biosynth PF02621.14 ABK69573.1 - 0.0032 17.0 0.2 0.02 14.4 0.1 1.9 2 0 0 2 2 2 1 Menaquinone biosynthesis MFS_1 PF07690.16 ABK69574.1 - 9.5e-66 222.1 45.9 9.5e-66 222.1 45.9 2.6 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.13 ABK69574.1 - 1.7e-07 30.0 36.5 9.5e-06 24.3 12.1 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector MFS_1_like PF12832.7 ABK69574.1 - 2.8e-07 29.7 22.0 0.00026 20.0 4.6 2.3 2 0 0 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 ABK69574.1 - 7.3e-07 28.4 7.1 7.3e-07 28.4 7.1 3.4 3 1 1 4 4 4 2 Sugar (and other) transporter LacY_symp PF01306.19 ABK69574.1 - 0.31 9.8 16.6 1.2 7.8 1.7 2.4 2 1 0 2 2 2 0 LacY proton/sugar symporter MFS_4 PF06779.14 ABK69574.1 - 7.4 5.8 46.4 0.21 10.8 14.7 3.7 2 2 1 3 3 3 0 Uncharacterised MFS-type transporter YbfB ERAP1_C PF11838.8 ABK69575.1 - 2.7e-59 201.3 0.5 4.4e-59 200.6 0.5 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 ABK69575.1 - 4.7e-58 196.3 0.7 9e-58 195.4 0.6 1.5 2 0 0 2 2 2 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 ABK69575.1 - 1.1e-19 71.4 0.0 1.9e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Bac_luciferase PF00296.20 ABK69576.1 - 2.5e-53 181.5 5.2 3.8e-53 180.9 5.2 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase Glycos_transf_1 PF00534.20 ABK69577.1 - 3.8e-23 81.9 0.0 6e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ABK69577.1 - 8e-22 78.0 1.3 1.6e-21 77.0 1.3 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 ABK69577.1 - 4e-20 72.6 0.4 8.9e-20 71.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 ABK69577.1 - 1.1e-12 48.7 2.6 1.1e-12 48.7 2.6 2.6 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 ABK69577.1 - 3.1e-05 24.3 0.0 7.6e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 FAA_hydrolase PF01557.18 ABK69583.1 - 1e-45 156.1 0.0 1.2e-45 155.8 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family ADH_N PF08240.12 ABK69584.1 - 2.1e-25 88.7 0.9 2.1e-25 88.7 0.9 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ABK69584.1 - 8.3e-20 71.1 0.9 1.7e-19 70.1 0.9 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ABK69584.1 - 0.0025 18.9 0.0 0.0051 17.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 ABK69584.1 - 0.015 14.7 0.3 0.025 13.9 0.3 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 ABK69584.1 - 0.027 14.7 0.3 0.057 13.7 0.3 1.6 1 0 0 1 1 1 0 TrkA-N domain ThiF PF00899.21 ABK69584.1 - 0.14 11.5 0.6 0.35 10.2 0.6 1.6 1 0 0 1 1 1 0 ThiF family Topoisom_bac PF01131.20 ABK69586.1 - 2.5e-121 405.6 0.0 3.2e-121 405.2 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim_C_rpt PF13368.6 ABK69586.1 - 8.8e-66 217.8 4.0 1e-20 73.5 0.0 4.6 4 0 0 4 4 4 4 Topoisomerase C-terminal repeat Toprim PF01751.22 ABK69586.1 - 4.9e-29 100.6 0.0 1.6e-28 98.9 0.0 1.9 2 0 0 2 2 2 1 Toprim domain Toprim_4 PF13662.6 ABK69586.1 - 5.8e-06 26.7 0.0 3.5e-05 24.2 0.0 2.4 1 1 0 1 1 1 1 Toprim domain MarR_2 PF12802.7 ABK69586.1 - 0.03 14.2 0.0 5.9 6.9 0.0 3.1 2 0 0 2 2 2 0 MarR family SBP_bac_3 PF00497.20 ABK69586.1 - 0.12 11.8 0.2 0.38 10.2 0.0 1.9 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 ADH_zinc_N PF00107.26 ABK69587.1 - 3.2e-23 82.1 0.3 4.7e-23 81.6 0.3 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ABK69587.1 - 1.1e-14 55.6 0.0 1.8e-14 54.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ABK69587.1 - 7.9e-11 41.8 0.3 2.8e-10 40.1 0.0 2.0 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 ABK69587.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Phage_integrase PF00589.22 ABK69588.1 - 3.6e-47 160.3 0.0 9.3e-47 159.0 0.0 1.6 2 0 0 2 2 2 1 Phage integrase family Phage_int_SAM_1 PF02899.17 ABK69588.1 - 8.1e-23 80.5 0.3 2.5e-22 79.0 0.1 2.0 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Integrase_1 PF12835.7 ABK69588.1 - 0.027 14.6 0.5 0.2 11.8 0.1 2.5 2 1 0 2 2 2 0 Integrase Phage_int_SAM_4 PF13495.6 ABK69588.1 - 0.027 14.9 0.0 0.078 13.5 0.0 1.7 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain DUF3435 PF11917.8 ABK69588.1 - 0.11 11.4 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) TPR_4 PF07721.14 ABK69588.1 - 2.9 8.8 7.8 33 5.5 0.2 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat FCD PF07729.12 ABK69589.1 - 4.3e-27 95.0 4.7 7e-27 94.3 4.7 1.3 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 ABK69589.1 - 4.8e-11 42.1 0.1 1.3e-10 40.8 0.1 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Fe_dep_repress PF01325.19 ABK69589.1 - 0.11 12.8 0.0 1.2 9.4 0.0 2.3 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain Glu_synthase PF01645.17 ABK69590.1 - 2.5e-86 290.1 0.0 3.1e-86 289.8 0.0 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase Rieske PF00355.26 ABK69590.1 - 3e-14 52.7 0.0 6.5e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain FMN_dh PF01070.18 ABK69590.1 - 6e-10 38.7 4.0 1.8e-09 37.1 2.4 2.0 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Rieske_2 PF13806.6 ABK69590.1 - 4.2e-05 23.4 0.0 8.1e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain IMPDH PF00478.25 ABK69590.1 - 0.00019 20.6 0.5 0.00042 19.4 0.5 1.6 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 ABK69590.1 - 0.0075 15.6 0.7 0.014 14.7 0.7 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 ABK69590.1 - 0.012 15.1 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein AIRC PF00731.20 ABK69591.1 - 4e-63 211.4 0.5 4.5e-63 211.3 0.5 1.0 1 0 0 1 1 1 1 AIR carboxylase Cupin_3 PF05899.12 ABK69592.1 - 4.6e-15 55.1 0.6 6.1e-15 54.7 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 ABK69592.1 - 0.029 14.1 0.1 0.053 13.2 0.1 1.4 1 0 0 1 1 1 0 Cupin domain AraC_binding_2 PF14525.6 ABK69592.1 - 0.04 13.6 0.3 0.049 13.3 0.3 1.3 1 1 0 1 1 1 0 AraC-binding-like domain SMC_ScpA PF02616.14 ABK69593.1 - 2.6e-75 253.5 0.0 3e-75 253.2 0.0 1.0 1 0 0 1 1 1 1 Segregation and condensation protein ScpA Methyltransf_2 PF00891.18 ABK69594.1 - 4.4e-50 169.9 0.0 5.5e-50 169.6 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 ABK69594.1 - 2.1e-08 34.0 0.0 7.6e-08 32.2 0.0 2.1 2 0 0 2 2 2 1 Dimerisation domain Methyltransf_12 PF08242.12 ABK69594.1 - 0.00067 20.4 0.0 0.0018 19.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain DprA_WH PF17782.1 ABK69594.1 - 0.0041 17.2 0.7 0.011 15.8 0.7 1.7 1 0 0 1 1 1 1 DprA winged helix domain Dimerisation PF08100.11 ABK69594.1 - 0.021 14.8 1.5 0.047 13.7 0.3 2.3 3 0 0 3 3 3 0 Dimerisation domain MarR_2 PF12802.7 ABK69594.1 - 0.041 13.8 1.2 0.12 12.3 1.2 1.8 1 0 0 1 1 1 0 MarR family Methyltransf_25 PF13649.6 ABK69594.1 - 0.06 14.1 0.0 0.16 12.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 ABK69594.1 - 0.19 11.3 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain LCM PF04072.14 ABK69595.1 - 3.2e-12 46.8 0.2 4.8e-11 42.9 0.2 2.4 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase DDE_3 PF13358.6 ABK69596.1 - 3e-24 85.4 0.0 4.5e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 ABK69596.1 - 4e-15 56.2 6.4 1.6e-14 54.3 0.7 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.6 ABK69596.1 - 9e-14 51.2 3.6 3.2e-13 49.5 0.4 3.2 3 0 0 3 3 3 1 Winged helix-turn helix HTH_28 PF13518.6 ABK69596.1 - 1.5e-13 50.6 5.9 3.5e-11 43.1 0.4 3.1 3 0 0 3 3 2 2 Helix-turn-helix domain HTH_23 PF13384.6 ABK69596.1 - 1.5e-12 46.9 1.7 3.6e-09 36.1 0.4 3.2 2 1 1 3 3 3 2 Homeodomain-like domain HTH_50 PF18024.1 ABK69596.1 - 0.00034 20.2 0.2 0.0013 18.3 0.0 2.1 3 0 0 3 3 2 1 Helix-turn-helix domain HTH_24 PF13412.6 ABK69596.1 - 0.00071 19.1 0.1 0.039 13.5 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_6 PF01418.17 ABK69596.1 - 0.001 19.0 0.0 0.0036 17.2 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain, rpiR family HTH_IclR PF09339.10 ABK69596.1 - 0.0015 18.3 0.6 0.059 13.2 0.0 2.4 2 0 0 2 2 2 1 IclR helix-turn-helix domain YdaS_antitoxin PF15943.5 ABK69596.1 - 0.003 17.4 0.2 0.9 9.5 0.0 2.9 3 0 0 3 3 3 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Sigma70_r4_2 PF08281.12 ABK69596.1 - 0.0046 16.6 0.0 0.051 13.3 0.0 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_26 PF13443.6 ABK69596.1 - 0.0058 17.0 0.6 0.99 9.9 0.0 3.1 3 0 0 3 3 3 1 Cro/C1-type HTH DNA-binding domain HTH_Crp_2 PF13545.6 ABK69596.1 - 0.0068 16.4 0.1 2.6 8.1 0.0 2.5 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_AsnC-type PF13404.6 ABK69596.1 - 0.0089 15.8 0.1 0.64 9.9 0.0 2.5 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_37 PF13744.6 ABK69596.1 - 0.026 14.5 0.0 0.47 10.5 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.7 ABK69596.1 - 0.034 14.3 0.4 3.3 8.0 0.0 3.1 3 0 0 3 3 2 0 Helix-turn-helix domain MarR PF01047.22 ABK69596.1 - 0.044 13.7 0.0 12 5.9 0.0 2.5 2 0 0 2 2 2 0 MarR family HTH_36 PF13730.6 ABK69596.1 - 0.044 13.7 0.0 0.34 10.9 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 ABK69596.1 - 0.048 14.2 1.5 0.056 14.0 0.1 1.8 2 0 0 2 2 1 0 leucine-zipper of insertion element IS481 HTH_Tnp_ISL3 PF13542.6 ABK69596.1 - 0.049 13.0 4.2 0.054 12.9 0.7 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4 PF04545.16 ABK69596.1 - 0.056 13.0 0.1 3.2 7.3 0.0 2.7 2 0 0 2 2 2 0 Sigma-70, region 4 GerE PF00196.19 ABK69596.1 - 0.084 12.4 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family DUF746 PF05344.11 ABK69596.1 - 0.13 12.1 0.8 2.5 8.0 0.0 3.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF746) HTH_3 PF01381.22 ABK69596.1 - 0.18 11.9 0.0 14 5.9 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix DGOK PF05035.12 ABK69598.1 - 2.9e-94 315.1 0.1 3.4e-94 314.9 0.1 1.0 1 0 0 1 1 1 1 2-keto-3-deoxy-galactonokinase Transp_cyt_pur PF02133.15 ABK69599.1 - 4.7e-53 180.5 42.4 8.4e-53 179.7 42.4 1.4 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin FGGY_N PF00370.21 ABK69600.1 - 2.1e-70 237.1 0.0 2.8e-70 236.7 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 ABK69600.1 - 8e-66 221.5 0.6 8.9e-65 218.1 0.6 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain HpcH_HpaI PF03328.14 ABK69601.1 - 1.5e-07 30.8 0.1 2.9e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family CCG PF02754.16 ABK69602.1 - 6.4e-33 112.8 1.3 2.3e-15 56.5 0.1 2.2 2 0 0 2 2 2 2 Cysteine-rich domain CPBP PF02517.16 ABK69603.1 - 4.3e-10 39.8 4.6 4.3e-10 39.8 4.6 2.3 2 0 0 2 2 2 1 CPBP intramembrane metalloprotease DUF2613 PF11021.8 ABK69603.1 - 0.076 13.1 1.7 0.076 13.1 1.7 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) AnmK PF03702.14 ABK69604.1 - 2.3e-130 434.9 1.5 2.6e-130 434.8 1.5 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase Chal_sti_synt_N PF00195.19 ABK69605.1 - 7.8e-16 58.2 0.1 1.2e-15 57.6 0.1 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.15 ABK69605.1 - 6.8e-15 55.4 0.0 1.3e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain FAE1_CUT1_RppA PF08392.12 ABK69605.1 - 1.3e-14 54.2 0.0 1.8e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.10 ABK69605.1 - 3.7e-10 39.8 0.0 5e-08 33.0 0.0 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Thiolase_N PF00108.23 ABK69605.1 - 0.0017 17.8 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain RACo_C_ter PF14574.6 ABK69605.1 - 0.05 12.6 0.0 0.084 11.9 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain of RACo the ASKHA domain HTH_31 PF13560.6 ABK69606.1 - 2.3e-12 47.1 1.5 2.3e-12 47.1 1.5 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 ABK69606.1 - 1.9e-10 40.7 0.1 2.7e-10 40.1 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 ABK69606.1 - 2.3e-08 34.0 0.0 3e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 ABK69606.1 - 7.3e-05 22.6 1.1 9.4e-05 22.2 0.1 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_26 PF13443.6 ABK69606.1 - 0.018 15.4 0.0 0.027 14.9 0.0 1.3 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain adh_short_C2 PF13561.6 ABK69607.1 - 1.1e-50 172.5 1.2 1.3e-50 172.2 1.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK69607.1 - 6.3e-42 143.2 0.1 7.4e-42 143.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK69607.1 - 1.6e-12 47.7 0.2 2.3e-12 47.2 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK69607.1 - 7.3e-08 32.2 0.4 2.1e-07 30.6 0.4 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ABK69607.1 - 0.0007 19.5 4.2 0.001 19.0 3.9 1.5 1 1 0 1 1 1 1 NAD(P)H-binding F420_oxidored PF03807.17 ABK69607.1 - 0.042 14.4 0.0 0.12 13.0 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 ABK69607.1 - 0.063 12.4 0.1 0.17 11.0 0.1 1.8 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 ABK69607.1 - 0.14 11.6 0.1 0.33 10.3 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Ribosomal_S11 PF00411.19 ABK69610.1 - 4.3e-49 165.5 0.9 5.8e-49 165.1 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 ELFV_dehydrog PF00208.21 ABK69610.1 - 0.0049 16.6 0.2 0.11 12.1 0.1 2.0 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Ribosomal_L18p PF00861.22 ABK69610.1 - 0.0051 17.2 0.5 0.007 16.7 0.5 1.3 1 1 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast HpcH_HpaI PF03328.14 ABK69611.1 - 5e-26 91.2 0.0 8.2e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 ABK69611.1 - 0.00086 18.5 0.0 0.37 9.9 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold adh_short_C2 PF13561.6 ABK69612.1 - 4.2e-62 209.8 0.0 4.8e-62 209.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK69612.1 - 4e-48 163.5 0.0 5e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK69612.1 - 7.8e-09 35.7 0.0 1.2e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK69612.1 - 0.0089 15.5 0.0 0.02 14.3 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 5TM-5TMR_LYT PF07694.12 ABK69612.1 - 0.056 13.0 1.0 0.085 12.4 1.0 1.3 1 0 0 1 1 1 0 5TMR of 5TMR-LYT F420_oxidored PF03807.17 ABK69612.1 - 0.06 13.9 0.1 0.18 12.4 0.1 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Bac_luciferase PF00296.20 ABK69613.1 - 9.8e-50 169.7 0.2 1.2e-49 169.5 0.2 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase CN_hydrolase PF00795.22 ABK69614.1 - 2.3e-38 132.0 0.0 2.9e-38 131.7 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase IDH PF03971.14 ABK69615.1 - 0 1256.0 0.0 0 1255.9 0.0 1.0 1 0 0 1 1 1 1 Monomeric isocitrate dehydrogenase ADH_N PF08240.12 ABK69616.1 - 2.2e-26 91.8 1.6 2.2e-26 91.8 1.6 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ABK69616.1 - 5.8e-20 71.6 0.8 1e-19 70.8 0.8 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ABK69616.1 - 6.4e-05 24.0 0.0 0.00011 23.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DIOX_N PF14226.6 ABK69618.1 - 1.2e-30 106.6 0.0 2e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ABK69618.1 - 2.6e-19 69.6 0.0 4.9e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_20 PF14561.6 ABK69619.1 - 6.2e-19 68.1 1.4 6.2e-19 68.1 1.4 2.4 1 1 0 2 2 2 1 Tetratricopeptide repeat Thioredoxin PF00085.20 ABK69619.1 - 2.8e-09 36.9 0.0 5.3e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin TPR_16 PF13432.6 ABK69619.1 - 3.7e-07 30.7 9.1 7.2e-07 29.7 8.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 ABK69619.1 - 9e-07 29.2 11.0 2.1e-06 28.0 0.8 3.9 1 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 ABK69619.1 - 6.4e-06 25.9 1.4 2.4e-05 24.1 1.4 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 ABK69619.1 - 1.2e-05 25.7 1.1 1.2e-05 25.7 1.1 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 ABK69619.1 - 8.1e-05 22.3 0.6 0.0002 21.0 0.6 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 ABK69619.1 - 0.0001 22.6 1.4 0.00044 20.5 0.6 2.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 ABK69619.1 - 0.00064 19.6 0.1 0.0026 17.7 0.1 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 ABK69619.1 - 0.0012 18.9 0.2 0.0026 17.8 0.2 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Thioredoxin_6 PF13848.6 ABK69619.1 - 0.0016 18.4 0.0 0.0023 17.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_2 PF13098.6 ABK69619.1 - 0.003 18.0 0.0 0.0065 16.9 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain KaiB PF07689.12 ABK69619.1 - 0.0057 16.4 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 KaiB domain TPR_4 PF07721.14 ABK69619.1 - 0.007 16.9 3.1 0.026 15.1 0.9 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 ABK69619.1 - 0.009 16.6 0.2 0.009 16.6 0.2 2.4 3 0 0 3 3 2 1 Tetratricopeptide repeat TrbC_Ftype PF09673.10 ABK69619.1 - 0.03 14.4 0.0 0.062 13.3 0.0 1.6 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein TPR_11 PF13414.6 ABK69619.1 - 0.032 13.9 0.3 0.032 13.9 0.3 2.9 3 1 1 4 4 4 0 TPR repeat TPR_9 PF13371.6 ABK69619.1 - 0.067 13.3 2.9 0.2 11.8 0.1 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ABK69619.1 - 0.081 13.0 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 ABK69619.1 - 0.088 12.7 2.9 0.093 12.6 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Thioredoxin_4 PF13462.6 ABK69619.1 - 0.25 11.5 0.6 3.6 7.7 0.0 2.3 2 1 0 2 2 2 0 Thioredoxin Peptidase_S8 PF00082.22 ABK69620.1 - 1.8e-37 129.2 2.5 3.5e-37 128.3 2.5 1.4 1 1 0 1 1 1 1 Subtilase family Amidase PF01425.21 ABK69621.1 - 5e-89 299.3 0.9 9.3e-88 295.1 0.9 2.3 1 1 0 1 1 1 1 Amidase WEMBL PF05701.11 ABK69621.1 - 1 7.9 2.1 1.5 7.4 2.1 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light CP_ATPgrasp_1 PF04174.13 ABK69622.1 - 1.1e-162 540.8 0.2 1.5e-162 540.3 0.2 1.2 1 0 0 1 1 1 1 A circularly permuted ATPgrasp CP_ATPgrasp_2 PF14403.6 ABK69622.1 - 6.1e-162 538.8 0.1 7.4e-162 538.5 0.1 1.1 1 0 0 1 1 1 1 Circularly permuted ATP-grasp type 2 ATPgrasp_YheCD PF14398.6 ABK69622.1 - 2.3e-05 23.8 0.0 0.0032 16.8 0.0 2.9 2 1 0 2 2 2 1 YheC/D like ATP-grasp GSH-S_ATP PF02955.16 ABK69622.1 - 0.041 13.3 0.0 0.4 10.0 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic glutathione synthetase, ATP-grasp domain ATP-grasp_3 PF02655.14 ABK69622.1 - 0.15 12.1 0.1 1.3 9.1 0.0 2.4 3 0 0 3 3 3 0 ATP-grasp domain EAL PF00563.20 ABK69623.1 - 2.9e-65 220.1 0.0 1e-64 218.4 0.0 1.8 2 0 0 2 2 2 1 EAL domain GGDEF PF00990.21 ABK69623.1 - 2.2e-34 118.6 0.0 3.3e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain GAF PF01590.26 ABK69623.1 - 6.7e-08 33.2 0.2 3.3e-07 31.0 0.1 2.2 3 0 0 3 3 3 1 GAF domain GAF_2 PF13185.6 ABK69623.1 - 6.7e-08 32.9 0.3 1.4e-07 31.9 0.3 1.5 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 ABK69623.1 - 0.00094 19.5 0.0 0.0031 17.8 0.0 1.9 1 0 0 1 1 1 1 GAF domain Beta-lactamase2 PF13354.6 ABK69624.1 - 2.3e-34 118.8 0.0 2.8e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase enzyme family Peptidase_S11 PF00768.20 ABK69624.1 - 6.8e-07 29.0 0.0 9.9e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Peptidase_S13 PF02113.15 ABK69624.1 - 0.059 12.1 0.0 0.23 10.1 0.0 1.8 2 0 0 2 2 2 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family ABC_tran PF00005.27 ABK69625.1 - 2.5e-34 118.7 0.0 3.3e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 ABK69625.1 - 3.7e-15 56.2 0.1 9e-15 55.0 0.1 1.7 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region SMC_N PF02463.19 ABK69625.1 - 1.9e-05 24.2 0.0 2.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ABK69625.1 - 3.8e-05 23.7 0.0 0.049 13.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ABK69625.1 - 0.00027 21.2 0.3 0.0029 17.9 0.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ABK69625.1 - 0.00047 20.6 0.1 0.00066 20.1 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 ABK69625.1 - 0.0048 16.6 0.0 0.0085 15.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 ABK69625.1 - 0.0051 17.2 0.0 0.011 16.1 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 ABK69625.1 - 0.0085 15.8 0.0 3.2 7.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 ABK69625.1 - 0.0089 15.9 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase TniB PF05621.11 ABK69625.1 - 0.011 15.2 0.0 0.68 9.3 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein NB-ARC PF00931.22 ABK69625.1 - 0.061 12.5 0.0 0.09 11.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.14 ABK69625.1 - 0.069 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_13 PF13166.6 ABK69625.1 - 0.079 11.6 0.0 3.6 6.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 ABK69625.1 - 0.089 12.4 0.1 0.22 11.1 0.0 1.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.22 ABK69625.1 - 0.1 13.0 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 ABK69625.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain PRK PF00485.18 ABK69625.1 - 0.22 11.3 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Oxidored_q6 PF01058.22 ABK69626.1 - 2.6e-24 85.5 0.1 3.6e-24 85.1 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit adh_short PF00106.25 ABK69627.1 - 2.5e-30 105.4 0.0 3.5e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK69627.1 - 4.3e-28 98.5 0.2 5.5e-28 98.1 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK69627.1 - 1.1e-06 28.7 0.1 1.7e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 KR domain DFP PF04127.15 ABK69627.1 - 0.036 13.9 0.2 0.065 13.1 0.2 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein 2-Hacid_dh_C PF02826.19 ABK69627.1 - 0.11 11.8 0.1 0.21 10.9 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 ABK69627.1 - 0.18 10.9 0.1 0.26 10.4 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 ABK69627.1 - 0.25 11.2 2.1 0.59 10.0 2.1 1.7 1 1 0 1 1 1 0 NAD(P)H-binding DUF3320 PF11784.8 ABK69628.1 - 7.1e-06 25.9 0.5 9.2e-05 22.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3320) Aminotran_5 PF00266.19 ABK69629.1 - 8.5e-19 67.7 0.0 2.1e-18 66.5 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V G6PD_C PF02781.16 ABK69630.1 - 1.4e-111 372.4 0.0 1.7e-111 372.1 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 ABK69630.1 - 5.5e-63 212.8 0.0 7.9e-63 212.3 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF4440 PF14534.6 ABK69631.1 - 0.012 16.0 1.4 0.028 14.8 1.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) RskA PF10099.9 ABK69631.1 - 0.027 14.8 0.2 0.035 14.4 0.2 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA ODV-E18 PF10717.9 ABK69631.1 - 0.031 14.1 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF4878 PF12870.7 ABK69631.1 - 0.065 13.5 0.1 0.13 12.5 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4878) Lumazine_bd_2 PF12893.7 ABK69631.1 - 0.07 13.8 0.0 0.1 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative lumazine-binding IMPDH PF00478.25 ABK69632.1 - 9.2e-154 511.6 8.2 1e-153 511.4 8.2 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 ABK69632.1 - 2.3e-21 76.0 0.8 2e-09 37.7 0.1 3.0 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 ABK69632.1 - 2.2e-09 37.2 12.5 1.2e-05 24.8 9.9 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 ABK69632.1 - 1.5e-07 30.8 9.5 2.1e-06 27.0 8.2 2.3 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 ABK69632.1 - 0.00016 21.3 4.1 0.23 10.9 0.9 2.3 1 1 0 2 2 2 2 Histidine biosynthesis protein Glu_synthase PF01645.17 ABK69632.1 - 0.005 16.0 6.2 0.0087 15.2 6.2 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase PRC PF05239.16 ABK69632.1 - 0.086 12.9 0.4 2.3 8.3 0.0 2.8 2 1 0 2 2 2 0 PRC-barrel domain DHO_dh PF01180.21 ABK69632.1 - 0.9 8.7 6.1 1 8.5 0.9 2.2 1 1 1 2 2 2 0 Dihydroorotate dehydrogenase ThiG PF05690.14 ABK69632.1 - 0.99 8.7 15.9 4.4 6.5 5.1 3.9 4 1 1 5 5 5 0 Thiazole biosynthesis protein ThiG AMP-binding PF00501.28 ABK69633.1 - 1.9e-71 240.9 0.3 4.2e-71 239.8 0.3 1.4 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK69633.1 - 1.1e-19 71.2 0.9 2.4e-19 70.1 0.9 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short PF00106.25 ABK69634.1 - 2.9e-40 137.8 0.0 3.9e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK69634.1 - 7.6e-37 127.1 0.2 9.9e-37 126.7 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK69634.1 - 0.0007 19.6 1.3 0.0065 16.4 1.3 2.2 1 1 0 1 1 1 1 KR domain TrkA_N PF02254.18 ABK69634.1 - 0.0031 17.8 0.0 0.0062 16.8 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.21 ABK69634.1 - 0.01 15.3 0.1 0.016 14.7 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 ABK69634.1 - 0.011 15.7 0.5 0.02 14.9 0.5 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase LpxI_N PF17930.1 ABK69634.1 - 0.014 15.3 0.0 0.24 11.3 0.1 2.4 3 0 0 3 3 3 0 LpxI N-terminal domain 2-Hacid_dh_C PF02826.19 ABK69634.1 - 0.033 13.5 0.1 0.049 13.0 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 ABK69634.1 - 0.075 12.9 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Acyl-CoA_dh_1 PF00441.24 ABK69635.1 - 1.8e-28 99.6 1.5 2.8e-28 99.0 1.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK69635.1 - 6.1e-19 68.0 0.0 1e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ABK69635.1 - 8.9e-17 61.8 0.4 3.2e-16 60.0 0.0 2.1 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ABK69635.1 - 7.4e-09 36.0 0.0 1.7e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 ABK69635.1 - 1.6e-05 24.7 0.0 5.1e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Guanylate_cyc PF00211.20 ABK69636.1 - 2.1e-12 47.0 0.0 3.6e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain CBP_BcsS PF17036.5 ABK69636.1 - 0.067 13.1 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsS Sulphotransf PF09037.10 ABK69637.1 - 4.2e-105 350.7 0.3 4.8e-105 350.5 0.3 1.0 1 0 0 1 1 1 1 Stf0 sulphotransferase Sulfotransfer_3 PF13469.6 ABK69637.1 - 3.5e-05 24.3 0.0 0.21 11.9 0.0 2.4 2 0 0 2 2 2 2 Sulfotransferase family DUF2236 PF09995.9 ABK69638.1 - 2.2e-47 162.2 4.1 2.8e-47 161.8 4.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) MerR_1 PF13411.6 ABK69639.1 - 2.8e-18 65.8 0.0 4e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 ABK69639.1 - 8.6e-16 57.4 1.7 2e-15 56.3 1.7 1.7 1 0 0 1 1 1 1 MerR family regulatory protein AbiEi_4 PF13338.6 ABK69639.1 - 0.0057 16.8 0.5 0.012 15.7 0.1 1.8 2 0 0 2 2 2 1 Transcriptional regulator, AbiEi antitoxin HTH_3 PF01381.22 ABK69639.1 - 0.039 14.0 0.1 0.089 12.9 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix HTH_28 PF13518.6 ABK69639.1 - 0.29 11.3 2.3 1.4 9.2 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain ADH_zinc_N PF00107.26 ABK69640.1 - 1.2e-25 89.9 1.1 1.9e-25 89.4 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ABK69640.1 - 2.6e-25 88.4 0.5 4.3e-25 87.7 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ABK69640.1 - 9e-10 39.7 0.1 1.5e-09 39.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 ABK69640.1 - 0.039 14.2 0.0 0.074 13.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain YitT_membrane PF02588.15 ABK69641.1 - 0.0094 15.3 10.7 0.035 13.5 1.3 2.1 2 0 0 2 2 2 2 Uncharacterised 5xTM membrane BCR, YitT family COG1284 p450 PF00067.22 ABK69642.1 - 7.2e-74 249.2 0.0 9.4e-74 248.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Phasin_2 PF09361.10 ABK69642.1 - 0.13 12.5 0.3 0.55 10.5 0.1 2.0 2 0 0 2 2 2 0 Phasin protein TctC PF03401.14 ABK69643.1 - 3e-43 147.9 0.0 3.6e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter family receptor Phosphonate-bd PF12974.7 ABK69643.1 - 0.014 15.0 0.1 0.02 14.5 0.1 1.4 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein DUF4995 PF16386.5 ABK69643.1 - 0.024 14.6 0.0 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function GntR PF00392.21 ABK69644.1 - 1.5e-15 56.6 0.4 4.2e-15 55.1 0.4 1.9 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family FCD PF07729.12 ABK69644.1 - 2.9e-14 53.5 13.2 2.9e-14 53.5 13.2 2.1 1 1 1 2 2 2 1 FCD domain Rrf2 PF02082.20 ABK69644.1 - 5.3e-06 26.7 0.1 1.6e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 Transcriptional regulator HTH_DeoR PF08220.12 ABK69644.1 - 0.003 17.3 0.2 0.011 15.5 0.0 2.1 2 1 0 2 2 2 1 DeoR-like helix-turn-helix domain HrcA_DNA-bdg PF03444.15 ABK69644.1 - 0.0073 15.9 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding HTH_IclR PF09339.10 ABK69644.1 - 0.028 14.2 2.7 0.063 13.1 0.1 2.7 3 0 0 3 3 3 0 IclR helix-turn-helix domain HTH_10 PF04967.12 ABK69644.1 - 0.051 13.4 0.1 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 HTH DNA binding domain HTH_5 PF01022.20 ABK69644.1 - 0.06 13.2 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 ABK69644.1 - 0.06 13.2 0.2 0.06 13.2 0.2 2.9 3 0 0 3 3 3 0 MarR family DUF746 PF05344.11 ABK69644.1 - 0.08 12.8 0.2 1.4 8.8 0.1 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) AAA_lid_6 PF17866.1 ABK69644.1 - 0.4 10.9 4.7 2.3 8.5 0.1 3.1 3 0 0 3 3 3 0 AAA lid domain HTH_20 PF12840.7 ABK69644.1 - 0.83 9.8 7.5 0.25 11.4 0.3 3.0 3 1 0 3 3 3 0 Helix-turn-helix domain Peripla_BP_4 PF13407.6 ABK69646.1 - 1.6e-39 136.0 4.7 2.4e-39 135.5 4.7 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 ABK69646.1 - 4.3e-14 52.6 0.4 8.2e-14 51.7 0.4 1.4 1 1 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 ABK69646.1 - 7.8e-05 23.1 0.0 0.00046 20.5 0.0 2.0 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Bac_luciferase PF00296.20 ABK69647.1 - 6e-46 157.3 3.9 1.1e-45 156.5 3.9 1.4 1 1 0 1 1 1 1 Luciferase-like monooxygenase PhetRS_B1 PF18262.1 ABK69647.1 - 0.035 14.3 0.1 0.065 13.5 0.1 1.4 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain LEM PF03020.15 ABK69647.1 - 0.092 12.3 0.0 0.33 10.6 0.0 1.9 2 0 0 2 2 2 0 LEM domain DUF3898 PF13037.6 ABK69647.1 - 0.19 11.9 0.0 15 5.7 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3898) TetR_N PF00440.23 ABK69648.1 - 1.2e-07 31.4 0.3 2.4e-07 30.4 0.3 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_7 PF02796.15 ABK69648.1 - 0.0047 17.0 0.0 0.009 16.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_31 PF13560.6 ABK69648.1 - 0.02 15.3 0.9 0.02 15.3 0.9 2.5 3 1 0 3 3 3 0 Helix-turn-helix domain HTH_22 PF13309.6 ABK69648.1 - 0.024 14.7 0.1 0.052 13.6 0.1 1.5 1 0 0 1 1 1 0 HTH domain HTH_11 PF08279.12 ABK69648.1 - 0.061 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 HTH domain HTH_23 PF13384.6 ABK69648.1 - 0.091 12.6 3.0 0.51 10.2 0.1 3.0 3 0 0 3 3 3 0 Homeodomain-like domain HTH_3 PF01381.22 ABK69648.1 - 0.12 12.5 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix DUF962 PF06127.11 ABK69649.1 - 0.043 13.9 0.3 0.1 12.7 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF962) DUF2269 PF10027.9 ABK69649.1 - 0.048 13.7 10.3 1.1 9.3 5.6 2.1 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2269) XdhC_C PF13478.6 ABK69650.1 - 1.1e-43 148.7 0.4 4.3e-43 146.8 0.2 1.9 2 0 0 2 2 2 1 XdhC Rossmann domain XdhC_CoxI PF02625.16 ABK69650.1 - 3.3e-36 123.3 19.3 2.9e-19 69.0 5.3 3.2 3 0 0 3 3 3 2 XdhC and CoxI family EamA PF00892.20 ABK69651.1 - 0.13 12.4 28.5 2.6 8.2 3.9 4.9 3 2 1 4 4 4 0 EamA-like transporter family Aminotran_3 PF00202.21 ABK69652.1 - 9.4e-132 439.5 0.2 1.1e-131 439.3 0.2 1.0 1 0 0 1 1 1 1 Aminotransferase class-III PsbN PF02468.15 ABK69653.1 - 0.45 10.4 2.7 0.51 10.2 2.7 1.1 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) ROK PF00480.20 ABK69654.1 - 4.5e-68 229.9 1.3 5e-68 229.7 1.3 1.0 1 0 0 1 1 1 1 ROK family FGGY_N PF00370.21 ABK69654.1 - 0.19 11.3 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain TetR_N PF00440.23 ABK69655.1 - 1e-16 60.5 0.0 1.9e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_15 PF17918.1 ABK69655.1 - 3.7e-07 30.9 0.6 3.7e-07 30.9 0.6 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_24 PF17932.1 ABK69655.1 - 3.5e-06 27.2 0.1 5.9e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_6 PF13977.6 ABK69655.1 - 0.00067 19.9 1.0 0.0014 18.9 1.0 1.5 1 0 0 1 1 1 1 BetI-type transcriptional repressor, C-terminal TetR_C_32 PF09209.11 ABK69655.1 - 0.054 13.5 0.1 0.096 12.7 0.1 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TetR_C_33 PF13305.6 ABK69655.1 - 0.11 13.2 1.8 0.2 12.4 0.8 2.0 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Pyr_redox_2 PF07992.14 ABK69656.1 - 7.9e-40 136.9 1.5 1e-39 136.6 1.5 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ABK69656.1 - 5.2e-12 46.2 0.2 3.1e-07 30.9 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ABK69656.1 - 4.2e-06 26.8 2.0 0.056 13.4 0.0 3.6 2 1 1 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 ABK69656.1 - 7.4e-06 25.3 0.0 0.0084 15.3 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 ABK69656.1 - 7.4e-06 25.3 2.4 0.0018 17.4 0.0 2.7 2 1 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 ABK69656.1 - 9.6e-06 25.7 2.1 0.0088 16.3 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 ABK69656.1 - 0.0002 20.6 5.8 0.14 11.2 0.0 2.6 2 1 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.24 ABK69656.1 - 0.00037 20.2 9.8 0.0075 15.9 0.1 3.2 2 2 1 3 3 3 1 FAD dependent oxidoreductase TrkA_N PF02254.18 ABK69656.1 - 0.0005 20.3 1.1 0.12 12.7 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain FAD_binding_2 PF00890.24 ABK69656.1 - 0.00084 18.5 4.6 0.066 12.3 0.0 2.5 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 ABK69656.1 - 0.0018 17.1 2.1 0.13 10.9 0.0 3.2 4 0 0 4 4 4 1 HI0933-like protein ApbA PF02558.16 ABK69656.1 - 0.0044 16.7 2.0 1.6 8.3 0.0 2.4 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 ABK69656.1 - 0.0077 15.5 0.6 0.27 10.4 0.0 2.6 3 0 0 3 3 3 1 Thi4 family NAD_binding_7 PF13241.6 ABK69656.1 - 0.01 16.2 0.4 0.16 12.5 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 ABK69656.1 - 0.011 15.8 0.3 1.6 8.8 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 ABK69656.1 - 0.015 15.5 2.0 0.26 11.5 0.0 2.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 ABK69656.1 - 0.016 15.1 1.4 1.6 8.5 0.6 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 ABK69656.1 - 0.018 14.3 0.0 1.2 8.3 0.0 2.2 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ABK69656.1 - 0.021 13.7 3.3 0.041 12.7 0.0 2.8 3 1 1 4 4 4 0 Tryptophan halogenase FAD_binding_3 PF01494.19 ABK69656.1 - 0.031 13.5 5.3 1.5 8.0 0.0 3.1 3 0 0 3 3 3 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 ABK69656.1 - 0.031 13.8 0.5 4.1 6.9 0.5 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GMC_oxred_N PF00732.19 ABK69656.1 - 0.041 13.3 0.4 0.087 12.2 0.0 1.7 2 0 0 2 2 2 0 GMC oxidoreductase FAD_binding_4 PF01565.23 ABK69656.1 - 0.1 12.4 2.5 0.081 12.7 0.5 2.0 2 0 0 2 2 2 0 FAD binding domain Peptidase_S28 PF05577.12 ABK69656.1 - 0.18 10.5 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 DUF1188 PF06690.11 ABK69656.1 - 0.24 10.9 0.0 6.2 6.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) AlaDh_PNT_C PF01262.21 ABK69656.1 - 0.25 10.6 6.0 0.66 9.2 0.0 3.0 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 ABK69656.1 - 0.33 10.2 5.0 6.9 5.9 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase PadR PF03551.14 ABK69657.1 - 3.8e-12 46.0 0.0 5.5e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family Vir_act_alpha_C PF10400.9 ABK69657.1 - 9e-12 45.5 0.2 1.5e-11 44.8 0.2 1.4 1 0 0 1 1 1 1 Virulence activator alpha C-term AphA_like PF14557.6 ABK69657.1 - 0.00024 20.9 0.1 0.00027 20.7 0.1 1.1 1 0 0 1 1 1 1 Putative AphA-like transcriptional regulator HTH_20 PF12840.7 ABK69657.1 - 0.0093 16.0 0.2 0.39 10.8 0.0 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_34 PF13601.6 ABK69657.1 - 0.012 15.8 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_27 PF13463.6 ABK69657.1 - 0.083 13.4 0.0 0.29 11.7 0.0 2.0 1 0 0 1 1 1 0 Winged helix DNA-binding domain HxlR PF01638.17 ABK69657.1 - 0.13 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 HxlR-like helix-turn-helix HTH_32 PF13565.6 ABK69657.1 - 0.16 12.6 0.6 0.35 11.5 0.6 1.7 1 1 0 1 1 1 0 Homeodomain-like domain TrmB PF01978.19 ABK69657.1 - 0.18 11.7 0.0 0.28 11.1 0.0 1.4 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB CHASE3 PF05227.13 ABK69658.1 - 1e-24 87.0 1.7 1e-24 87.0 1.7 2.2 2 0 0 2 2 2 1 CHASE3 domain HATPase_c PF02518.26 ABK69658.1 - 1.5e-23 83.4 0.0 3.1e-23 82.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ABK69658.1 - 2.3e-12 46.7 0.1 1.9e-11 43.8 0.0 2.5 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 ABK69658.1 - 3.9e-07 30.4 0.2 3.9e-07 30.4 0.2 2.4 2 0 0 2 2 2 1 HAMP domain DUF2798 PF11391.8 ABK69658.1 - 0.004 17.2 0.2 0.01 15.9 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2798) HATPase_c_3 PF13589.6 ABK69658.1 - 0.037 13.8 0.0 0.084 12.7 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MFS_1 PF07690.16 ABK69661.1 - 2.3e-42 145.2 51.5 2.3e-42 145.2 51.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ABK69661.1 - 1.8e-05 24.2 11.0 1.8e-05 24.2 11.0 2.5 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB F420_ligase PF01996.16 ABK69662.1 - 1.8e-42 145.4 0.2 9.5e-40 136.5 0.2 2.1 1 1 0 1 1 1 1 F420-0:Gamma-glutamyl ligase Nitroreductase PF00881.24 ABK69662.1 - 5.2e-28 98.2 0.0 8.2e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 ABK69662.1 - 3.2e-05 23.6 0.0 0.011 15.3 0.0 2.7 2 1 1 3 3 3 1 Putative TM nitroreductase Phosphonate-bd PF12974.7 ABK69662.1 - 0.024 14.3 0.1 1.8 8.1 0.0 2.4 1 1 1 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein MFS_1 PF07690.16 ABK69663.1 - 1.8e-26 92.9 72.8 1.9e-24 86.3 40.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK69663.1 - 2.6e-13 49.6 0.8 2.6e-13 49.6 0.8 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 ABK69663.1 - 0.0049 15.8 1.9 0.0049 15.8 1.9 2.4 2 1 0 2 2 2 1 MFS_1 like family MFS_2 PF13347.6 ABK69663.1 - 0.076 11.6 18.3 0.048 12.2 0.2 2.9 2 1 0 2 2 2 0 MFS/sugar transport protein ABC_tran PF00005.27 ABK69664.1 - 2.2e-35 122.2 0.0 3e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ABK69664.1 - 6.5e-10 38.8 0.4 1.6e-06 27.7 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ABK69664.1 - 2e-09 37.7 0.0 0.0008 19.3 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ABK69664.1 - 1e-05 25.9 0.1 0.00014 22.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ABK69664.1 - 0.00031 21.2 0.0 0.00048 20.5 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 ABK69664.1 - 0.00066 19.4 0.1 0.0013 18.4 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 ABK69664.1 - 0.0013 18.9 0.5 0.025 14.8 0.5 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 ABK69664.1 - 0.002 18.1 0.0 0.0037 17.2 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 ABK69664.1 - 0.0029 18.2 0.0 0.006 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 ABK69664.1 - 0.0029 17.3 0.0 0.064 13.0 0.0 2.6 2 1 1 3 3 3 1 IstB-like ATP binding protein AAA_33 PF13671.6 ABK69664.1 - 0.0035 17.5 0.0 0.0047 17.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 ABK69664.1 - 0.0048 16.6 0.0 0.0049 16.6 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 ABK69664.1 - 0.0055 16.5 0.2 0.022 14.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ABK69664.1 - 0.0075 16.3 0.3 0.83 9.6 0.0 2.6 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 ABK69664.1 - 0.0077 16.0 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 ABK69664.1 - 0.009 16.5 0.1 0.015 15.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 ABK69664.1 - 0.018 13.9 1.5 2.9 6.6 0.2 2.5 2 1 0 2 2 2 0 Predicted ATPase of the ABC class NACHT PF05729.12 ABK69664.1 - 0.019 14.9 0.0 0.068 13.1 0.0 2.0 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 ABK69664.1 - 0.035 13.7 0.0 0.072 12.7 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.18 ABK69664.1 - 0.039 13.7 0.0 0.086 12.6 0.0 1.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 ABK69664.1 - 0.049 13.6 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain T2SSE PF00437.20 ABK69664.1 - 0.05 12.7 0.1 0.1 11.6 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA PF00004.29 ABK69664.1 - 0.053 13.9 0.3 2.8 8.4 0.3 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 ABK69664.1 - 0.054 12.8 0.0 0.08 12.2 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_14 PF13173.6 ABK69664.1 - 0.057 13.4 0.0 0.18 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ABK69664.1 - 0.058 13.0 2.0 0.41 10.2 0.1 2.6 1 1 2 3 3 3 0 AAA domain CobU PF02283.16 ABK69664.1 - 0.075 12.6 0.1 5 6.7 0.0 2.7 3 1 0 3 3 3 0 Cobinamide kinase / cobinamide phosphate guanyltransferase CSD2 PF17876.1 ABK69664.1 - 0.077 13.2 0.4 11 6.2 0.0 2.8 2 1 1 3 3 2 0 Cold shock domain PRK PF00485.18 ABK69664.1 - 0.088 12.5 0.0 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ATP_bind_1 PF03029.17 ABK69664.1 - 0.097 12.4 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 ABK69664.1 - 0.099 12.9 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 ABK69664.1 - 0.12 12.0 0.1 0.17 11.5 0.1 1.5 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.23 ABK69664.1 - 0.14 12.3 0.0 0.18 11.9 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF3483 PF11982.8 ABK69665.1 - 0.0018 17.9 4.3 0.002 17.8 4.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3483) YtpI PF14007.6 ABK69665.1 - 0.0076 16.4 0.2 0.01 15.9 0.2 1.3 1 0 0 1 1 1 1 YtpI-like protein Phage_holin_3_6 PF07332.11 ABK69665.1 - 0.098 12.7 10.3 0.031 14.3 7.8 1.5 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF202 PF02656.15 ABK69665.1 - 0.36 11.3 8.7 0.21 12.0 6.4 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF4307 PF14155.6 ABK69665.1 - 9.9 6.0 7.3 1.3 8.9 2.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4307) AAA_19 PF13245.6 ABK69666.1 - 3.6e-12 46.8 1.4 9.8e-11 42.2 1.4 2.3 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 ABK69666.1 - 3.1e-10 40.1 0.3 0.00038 20.1 0.0 2.2 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 ABK69666.1 - 6.9e-06 25.8 0.7 2.9e-05 23.8 0.0 2.5 3 0 0 3 3 3 1 UvrD-like helicase C-terminal domain DUF2075 PF09848.9 ABK69666.1 - 1e-05 25.0 0.5 0.00028 20.3 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 ABK69666.1 - 3.4e-05 23.7 0.2 0.11 12.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 ABK69666.1 - 5.1e-05 22.8 0.0 0.17 11.4 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_11 PF13086.6 ABK69666.1 - 0.00014 21.8 0.0 0.00063 19.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 ABK69666.1 - 0.00041 20.2 0.0 0.007 16.1 0.0 2.6 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 ABK69666.1 - 0.0022 17.8 0.0 0.12 12.1 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.6 ABK69666.1 - 0.0055 17.0 1.1 1.7 8.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain UvrD_C PF13361.6 ABK69666.1 - 0.011 15.1 0.0 0.42 9.9 0.1 2.4 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain ResIII PF04851.15 ABK69666.1 - 0.21 11.6 0.1 0.7 9.9 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_21 PF13304.6 ABK69667.1 - 2.3e-29 103.2 0.1 1.1e-20 74.7 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 ABK69667.1 - 3e-18 66.7 0.0 6e-09 36.1 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 ABK69667.1 - 8.4e-11 41.7 0.0 2.5e-05 23.8 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF2813 PF11398.8 ABK69667.1 - 2.7e-06 26.9 0.4 0.00096 18.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2813) AAA_23 PF13476.6 ABK69667.1 - 1.5e-05 25.6 0.0 2.2e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 ABK69667.1 - 0.00082 19.9 0.1 0.0077 16.8 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_18 PF13238.6 ABK69667.1 - 0.0047 17.5 0.0 0.0091 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ABK69667.1 - 0.01 15.5 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 ABK69667.1 - 0.017 14.7 1.2 0.04 13.5 0.0 2.1 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 ABK69667.1 - 0.024 14.4 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ABK69667.1 - 0.031 14.7 3.6 0.18 12.2 0.1 2.6 2 1 1 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 ABK69667.1 - 0.072 13.4 0.1 0.2 11.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 ABK69667.1 - 0.077 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ABK69667.1 - 0.098 12.9 0.2 0.22 11.8 0.2 1.6 1 0 0 1 1 1 0 AAA domain COesterase PF00135.28 ABK69668.1 - 2e-110 370.1 0.0 4.2e-110 369.0 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ABK69668.1 - 9.6e-17 61.5 0.9 1.8e-15 57.3 0.8 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ABK69668.1 - 0.00043 19.8 0.0 0.00076 19.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 ABK69668.1 - 0.063 12.1 0.2 0.65 8.8 0.2 2.0 1 1 0 1 1 1 0 Steryl acetyl hydrolase NOB1_Zn_bind PF08772.11 ABK69669.1 - 0.0027 17.8 0.9 0.0036 17.4 0.9 1.2 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like DUF2614 PF11023.8 ABK69669.1 - 0.0068 16.5 0.8 0.0082 16.2 0.8 1.1 1 0 0 1 1 1 1 Zinc-ribbon containing domain zf-FCS PF06467.14 ABK69669.1 - 0.0088 16.0 1.4 0.28 11.2 0.0 2.1 2 0 0 2 2 2 1 MYM-type Zinc finger with FCS sequence motif zinc_ribbon_5 PF13719.6 ABK69669.1 - 2.7 7.8 5.7 12 5.8 0.4 2.3 2 0 0 2 2 2 0 zinc-ribbon domain adh_short_C2 PF13561.6 ABK69670.1 - 1.4e-39 136.1 1.8 2.7e-39 135.1 1.8 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK69670.1 - 2.6e-32 111.9 1.1 4.7e-32 111.0 1.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK69670.1 - 0.0031 17.5 0.1 0.013 15.4 0.0 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK69670.1 - 0.096 12.1 0.2 4.9 6.5 0.0 2.2 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family WES_acyltransf PF03007.16 ABK69671.1 - 2e-83 280.2 0.6 2.5e-83 279.9 0.6 1.1 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 ABK69671.1 - 8.1e-22 77.7 0.0 1.4e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) ApbA PF02558.16 ABK69672.1 - 1.2e-24 86.7 0.2 2.3e-24 85.7 0.2 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 ABK69672.1 - 4.9e-12 46.2 0.0 1.3e-11 44.8 0.0 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal CoA_binding_2 PF13380.6 ABK69672.1 - 0.0062 17.0 2.0 0.8 10.2 0.1 2.5 1 1 0 2 2 2 2 CoA binding domain FMN_dh PF01070.18 ABK69673.1 - 3e-13 49.5 1.7 5.6e-07 28.9 0.0 2.2 2 0 0 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.25 ABK69673.1 - 0.05 12.6 2.1 0.39 9.7 0.0 2.2 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 ABK69673.1 - 0.055 12.6 0.3 2.1 7.4 0.1 2.1 2 0 0 2 2 2 0 Conserved region in glutamate synthase DHO_dh PF01180.21 ABK69673.1 - 0.067 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase SIS PF01380.22 ABK69674.1 - 1.2e-30 106.1 0.1 5.4e-16 58.6 0.2 3.1 3 0 0 3 3 3 2 SIS domain GATase_6 PF13522.6 ABK69674.1 - 3.8e-21 75.7 0.2 7.8e-21 74.7 0.2 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 ABK69674.1 - 1e-14 54.5 0.0 1.8e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 ABK69674.1 - 0.00035 19.6 0.1 0.00057 18.9 0.1 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II EutH PF04346.12 ABK69674.1 - 0.043 13.0 0.1 0.071 12.3 0.1 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein, EutH Metallophos_2 PF12850.7 ABK69675.1 - 7.5e-09 36.0 0.0 8.7e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 ABK69675.1 - 1.2e-06 29.2 0.2 1.2e-05 25.9 0.0 1.8 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase MMPL PF03176.15 ABK69676.1 - 1.4e-217 721.1 34.3 5e-110 367.5 10.2 3.2 3 0 0 3 3 3 3 MMPL family OmpH PF03938.14 ABK69676.1 - 0.047 14.0 4.4 0.067 13.5 0.1 2.7 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) BLOC1_2 PF10046.9 ABK69676.1 - 0.17 12.2 2.7 13 6.2 0.2 3.3 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4763 PF15960.5 ABK69676.1 - 0.37 10.1 0.9 17 4.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) Prominin PF05478.11 ABK69676.1 - 0.93 7.4 9.1 0.041 11.9 1.1 2.5 2 1 0 2 2 2 0 Prominin ThiF PF00899.21 ABK69677.1 - 3.9e-58 196.7 0.0 5.3e-58 196.2 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 ABK69677.1 - 3.3e-15 56.5 0.0 9.5e-15 55.0 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.20 ABK69677.1 - 0.0095 16.0 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Mrr_N PF14338.6 ABK69677.1 - 0.087 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Mrr N-terminal domain DAO PF01266.24 ABK69677.1 - 0.12 11.9 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF3237 PF11578.8 ABK69678.1 - 2.1e-32 112.0 0.0 2.4e-32 111.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Cyt_c_ox_IV PF12270.8 ABK69679.1 - 8.7e-51 171.5 6.7 9.8e-51 171.3 6.7 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Phage_holin_3_6 PF07332.11 ABK69679.1 - 0.011 15.8 15.2 0.011 15.8 1.8 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Trp_oprn_chp PF09534.10 ABK69679.1 - 0.23 11.3 7.3 0.48 10.2 7.3 1.5 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4231 PF14015.6 ABK69679.1 - 5.6 7.5 10.4 0.7 10.4 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) HhH-GPD PF00730.25 ABK69680.1 - 5.6e-23 81.5 0.0 8.5e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 ABK69680.1 - 2.3e-10 39.8 0.7 6.2e-10 38.4 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 ABK69680.1 - 1.9e-05 24.9 4.7 3.2e-05 24.1 4.7 1.4 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III HHH_5 PF14520.6 ABK69680.1 - 0.042 14.5 0.1 0.47 11.1 0.0 2.6 3 0 0 3 3 3 0 Helix-hairpin-helix domain DUF763 PF05559.11 ABK69680.1 - 0.12 11.6 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Aldedh PF00171.22 ABK69681.1 - 6.6e-132 440.3 0.2 8.2e-132 440.0 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF302 PF03625.14 ABK69682.1 - 6.7e-24 83.6 0.1 9.9e-24 83.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF302 RraA-like PF03737.15 ABK69683.1 - 1.6e-31 109.5 0.0 2.1e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 Aldolase/RraA DUF2911 PF11138.8 ABK69683.1 - 0.2 11.5 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2911) Stomoxyn PF11585.8 ABK69683.1 - 0.67 10.0 4.2 1.7 8.7 1.6 2.4 2 0 0 2 2 2 0 Insect antimicrobial peptide, stomoxyn TP_methylase PF00590.20 ABK69684.1 - 2.8e-26 92.8 1.5 4.5e-26 92.1 1.5 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Amidohydro_2 PF04909.14 ABK69684.1 - 0.076 12.8 1.1 0.18 11.5 0.2 2.0 1 1 1 2 2 2 0 Amidohydrolase DUF3606 PF12244.8 ABK69684.1 - 0.13 12.2 0.5 19 5.3 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) Acyl-CoA_dh_N PF02771.16 ABK69685.1 - 9.7e-21 74.6 0.2 4.4e-20 72.4 0.1 2.2 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 ABK69685.1 - 1.6e-18 67.3 0.0 1e-17 64.7 0.0 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK69685.1 - 9.6e-16 57.8 0.0 1.8e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ABK69685.1 - 0.06 13.6 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 ABK69685.1 - 0.14 12.7 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal UPF0182 PF03699.13 ABK69686.1 - 4.7e-268 891.4 0.1 5.9e-268 891.1 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0182) DUF1282 PF06930.12 ABK69686.1 - 4.1 7.1 15.4 0.15 11.8 3.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1282) Mce4_CUP1 PF11887.8 ABK69687.1 - 1.4e-52 178.7 0.2 1.8e-52 178.3 0.2 1.1 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative MlaD PF02470.20 ABK69687.1 - 1.8e-09 37.8 0.0 3.2e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 MlaD protein DUF5642 PF18702.1 ABK69688.1 - 4.8e-74 248.1 0.6 5.7e-74 247.9 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5642) LVIVD PF08309.11 ABK69688.1 - 0.2 11.0 0.4 0.44 9.9 0.4 1.5 1 0 0 1 1 1 0 LVIVD repeat Glyco_tranf_2_3 PF13641.6 ABK69689.1 - 2.9e-10 40.4 0.0 4e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 ABK69689.1 - 3.4e-09 36.7 0.0 8.8e-09 35.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.6 ABK69689.1 - 0.0013 19.2 0.0 1.6 9.3 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 DUF3618 PF12277.8 ABK69690.1 - 4.9e-16 58.7 5.1 6.7e-16 58.3 5.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3618) FAD_binding_3 PF01494.19 ABK69691.1 - 3.4e-18 66.0 0.0 4.3e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ABK69691.1 - 1.4e-11 44.6 1.3 9.9e-05 22.1 0.1 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 ABK69691.1 - 2e-09 36.9 0.0 0.00036 19.5 0.0 2.2 1 1 0 2 2 2 2 Tryptophan halogenase FAD_oxidored PF12831.7 ABK69691.1 - 2.9e-07 30.2 1.6 5.7e-07 29.2 1.6 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 ABK69691.1 - 5.1e-07 29.1 0.3 0.00016 20.9 0.1 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 ABK69691.1 - 1e-06 28.3 0.2 0.00097 18.5 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ABK69691.1 - 1.3e-06 27.4 0.1 0.00011 21.0 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 ABK69691.1 - 1.6e-05 24.2 0.7 0.00032 19.9 0.2 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 ABK69691.1 - 2.1e-05 24.7 0.3 5.3e-05 23.4 0.1 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ABK69691.1 - 0.00068 20.2 0.0 0.072 13.7 0.0 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ABK69691.1 - 0.0028 16.7 1.8 0.022 13.8 0.8 2.5 2 1 0 2 2 2 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 ABK69691.1 - 0.0053 16.1 0.1 0.0082 15.5 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 ABK69691.1 - 0.016 14.4 0.0 0.041 13.1 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 ABK69691.1 - 0.03 13.6 0.1 0.052 12.8 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_trans_4_4 PF13579.6 ABK69691.1 - 0.041 14.3 0.5 0.22 11.9 0.1 2.1 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain AAA_16 PF13191.6 ABK69692.1 - 8.4e-19 68.6 1.2 8.4e-19 68.6 1.2 3.0 2 1 0 2 2 2 1 AAA ATPase domain GerE PF00196.19 ABK69692.1 - 9.5e-17 60.3 0.1 2.4e-16 59.0 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family NACHT PF05729.12 ABK69692.1 - 0.0013 18.7 0.0 0.0034 17.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 ABK69692.1 - 0.0062 16.8 0.1 0.048 13.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain DAP3 PF10236.9 ABK69692.1 - 0.037 13.2 0.3 0.22 10.6 0.1 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 NAD_binding_5 PF07994.12 ABK69692.1 - 0.063 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase TsaE PF02367.17 ABK69692.1 - 0.068 13.2 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE KAP_NTPase PF07693.14 ABK69692.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain AAA_30 PF13604.6 ABK69692.1 - 0.17 11.6 0.1 0.17 11.6 0.1 3.2 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 ABK69692.1 - 0.21 11.5 0.0 0.39 10.6 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_31 PF13614.6 ABK69693.1 - 1.8e-53 181.1 0.0 2.2e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 ABK69693.1 - 1.3e-25 89.9 0.0 2.3e-25 89.1 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 ABK69693.1 - 3.5e-12 46.3 0.0 4.5e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ArsA_ATPase PF02374.15 ABK69693.1 - 3.3e-09 36.4 0.1 1.2e-08 34.6 0.1 1.8 1 1 0 1 1 1 1 Anion-transporting ATPase MipZ PF09140.11 ABK69693.1 - 6.7e-09 35.4 0.2 0.00019 20.8 0.1 2.2 2 0 0 2 2 2 2 ATPase MipZ ParA PF10609.9 ABK69693.1 - 8.5e-09 35.2 0.1 2.6e-08 33.6 0.1 1.9 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 ABK69693.1 - 5.7e-05 22.7 0.0 0.00053 19.5 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.11 ABK69693.1 - 0.0055 16.0 0.2 0.014 14.7 0.1 1.6 2 0 0 2 2 2 1 VirC1 protein MeaB PF03308.16 ABK69693.1 - 0.071 12.1 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 ABK69693.1 - 0.12 12.2 0.0 0.26 11.0 0.0 1.7 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein Methyltransf_24 PF13578.6 ABK69693.1 - 0.14 13.2 0.0 0.26 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain SRP54 PF00448.22 ABK69693.1 - 0.14 11.7 0.6 0.23 11.1 0.1 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PRC PF05239.16 ABK69694.1 - 0.034 14.2 0.0 2.1 8.5 0.0 2.1 2 0 0 2 2 2 0 PRC-barrel domain NHL PF01436.21 ABK69694.1 - 0.11 12.5 0.1 0.28 11.3 0.1 1.7 1 0 0 1 1 1 0 NHL repeat DUF2982 PF11201.8 ABK69694.1 - 0.27 10.8 0.1 0.39 10.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2982) Aminotran_1_2 PF00155.21 ABK69695.1 - 8.2e-36 123.9 0.0 1e-35 123.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 ABK69695.1 - 0.0076 15.2 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Alliinase_C PF04864.13 ABK69695.1 - 0.012 14.5 0.0 0.042 12.7 0.0 1.7 1 1 0 1 1 1 0 Allinase DUF302 PF03625.14 ABK69695.1 - 0.062 13.2 0.0 1.8 8.5 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF302 Rhodanese PF00581.20 ABK69696.1 - 6.4e-18 65.2 0.0 9.3e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain DUF2892 PF11127.8 ABK69696.1 - 6.3e-10 39.0 3.0 1.2e-09 38.1 3.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2892) Chorismate_bind PF00425.18 ABK69697.1 - 3.1e-67 226.9 0.0 3.8e-67 226.6 0.0 1.1 1 0 0 1 1 1 1 chorismate binding enzyme Thiolase_N PF00108.23 ABK69698.1 - 5e-63 212.9 0.0 1.1e-62 211.7 0.0 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ABK69698.1 - 7.1e-47 158.1 1.1 1.3e-46 157.3 1.1 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ABK69698.1 - 0.011 15.4 1.9 0.16 11.5 0.0 2.9 2 1 1 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 ABK69698.1 - 0.046 13.6 0.1 3 7.8 0.0 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DDE_Tnp_1_4 PF13701.6 ABK69699.1 - 9.5e-69 231.7 0.0 1.1e-68 231.5 0.0 1.0 1 0 0 1 1 1 1 Transposase DDE domain group 1 DDE_Tnp_1 PF01609.21 ABK69699.1 - 0.0011 18.6 0.0 0.0021 17.7 0.0 1.5 1 1 0 1 1 1 1 Transposase DDE domain Putative_PNPOx PF01243.20 ABK69700.1 - 3.3e-20 72.0 0.0 5.7e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 ABK69700.1 - 1.2e-13 50.9 3.7 2e-13 50.2 1.6 2.4 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region HTH_3 PF01381.22 ABK69701.1 - 2.5e-15 56.3 0.4 3.6e-15 55.7 0.4 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 ABK69701.1 - 7.9e-15 55.0 0.1 1.3e-14 54.3 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 ABK69701.1 - 6.7e-10 38.8 0.0 9.7e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 ABK69701.1 - 4.8e-05 23.1 0.6 0.00028 20.7 0.6 2.0 1 1 0 1 1 1 1 Helix-turn-helix domain TetR_N PF00440.23 ABK69701.1 - 0.00071 19.3 0.3 0.18 11.6 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory proteins, tetR family HTH_26 PF13443.6 ABK69701.1 - 0.0023 18.3 0.0 0.0035 17.8 0.0 1.2 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain Rrf2 PF02082.20 ABK69701.1 - 0.0033 17.7 0.1 0.01 16.2 0.0 1.8 1 1 1 2 2 2 1 Transcriptional regulator HTH_37 PF13744.6 ABK69701.1 - 0.0034 17.3 0.3 0.0051 16.7 0.3 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Methyltransf_19 PF04672.12 ABK69701.1 - 0.0041 16.6 0.2 0.0054 16.2 0.2 1.1 1 0 0 1 1 1 1 S-adenosyl methyltransferase HTH_6 PF01418.17 ABK69701.1 - 0.012 15.5 0.4 0.14 12.2 0.1 2.2 1 1 1 2 2 2 0 Helix-turn-helix domain, rpiR family HTH_10 PF04967.12 ABK69701.1 - 0.091 12.6 0.5 1.3 8.9 0.0 2.7 3 0 0 3 3 3 0 HTH DNA binding domain HTH_35 PF13693.6 ABK69701.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding FTSW_RODA_SPOVE PF01098.19 ABK69702.1 - 4.3e-121 404.3 18.4 5.1e-121 404.0 18.4 1.0 1 0 0 1 1 1 1 Cell cycle protein ADH_zinc_N PF00107.26 ABK69703.1 - 3.3e-26 91.8 1.5 7.9e-26 90.6 1.5 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ABK69703.1 - 1.1e-22 80.0 0.4 1.1e-22 80.0 0.4 2.5 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 ABK69703.1 - 6.2e-11 42.2 0.9 1e-10 41.5 0.9 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 ABK69703.1 - 9.4e-11 42.9 0.1 1.9e-10 41.9 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ABK69703.1 - 9.6e-07 28.3 2.1 9.6e-07 28.3 2.1 1.9 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 ABK69703.1 - 4e-05 23.3 0.4 8.1e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 ABK69703.1 - 0.00069 19.9 0.1 0.0015 18.7 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.18 ABK69703.1 - 0.00082 19.3 0.3 0.0017 18.3 0.3 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 ABK69703.1 - 0.022 15.2 0.2 0.046 14.2 0.2 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain HI0933_like PF03486.14 ABK69703.1 - 0.044 12.5 0.8 0.099 11.3 0.8 1.6 1 0 0 1 1 1 0 HI0933-like protein ApoL PF05461.11 ABK69703.1 - 0.068 12.5 0.2 0.12 11.6 0.1 1.4 1 1 0 1 1 1 0 Apolipoprotein L 2-Hacid_dh_C PF02826.19 ABK69703.1 - 0.12 11.8 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MTS PF05175.14 ABK69703.1 - 0.16 11.5 0.1 0.52 9.8 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Pyr_redox_2 PF07992.14 ABK69703.1 - 0.9 8.7 6.7 0.33 10.1 1.0 2.1 1 1 2 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ABK69703.1 - 1.4 9.5 4.6 0.31 11.6 0.3 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ABK69703.1 - 4.9 6.4 6.3 2.2 7.5 2.9 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Acyl-CoA_dh_1 PF00441.24 ABK69704.1 - 4.1e-52 176.4 3.8 6.2e-52 175.8 3.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 ABK69704.1 - 1.6e-26 93.1 1.8 3.4e-26 92.1 1.8 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK69704.1 - 4.1e-23 81.4 0.0 7.1e-23 80.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ABK69704.1 - 1.1e-15 58.3 0.3 2.4e-15 57.2 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain DUF3054 PF11255.8 ABK69705.1 - 1.6e-35 122.0 14.4 1.8e-35 121.7 14.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3054) YbhQ PF11076.8 ABK69705.1 - 0.03 14.3 3.8 0.21 11.6 0.2 2.1 1 1 1 2 2 2 0 Putative inner membrane protein YbhQ FeoB_C PF07664.12 ABK69705.1 - 0.93 9.2 3.9 3.1 7.6 0.5 2.7 1 1 2 3 3 3 0 Ferrous iron transport protein B C terminus BPD_transp_1 PF00528.22 ABK69706.1 - 1.3e-18 67.3 21.5 1.3e-18 67.3 21.5 2.0 1 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component MatC_N PF07158.11 ABK69707.1 - 8.1e-53 178.5 39.0 2.1e-51 173.9 17.9 2.5 2 0 0 2 2 2 2 Dicarboxylate carrier protein MatC N-terminus CitMHS PF03600.16 ABK69707.1 - 1.8e-20 73.4 53.7 9.8e-11 41.4 26.7 2.3 1 1 1 2 2 2 2 Citrate transporter ATPase PF06745.13 ABK69709.1 - 1.2e-13 50.9 0.0 5.9e-11 42.2 0.0 2.2 1 1 1 2 2 2 2 KaiC AAA_25 PF13481.6 ABK69709.1 - 1.4e-11 44.4 3.1 6.7e-11 42.1 3.1 2.1 1 1 0 1 1 1 1 AAA domain Rubredoxin_2 PF18073.1 ABK69709.1 - 6.4e-10 38.6 5.8 9.6e-10 38.0 5.8 1.3 1 0 0 1 1 1 1 Rubredoxin metal binding domain DnaB_C PF03796.15 ABK69709.1 - 5.6e-08 32.4 0.0 1.2e-05 24.8 0.0 2.2 1 1 0 2 2 2 1 DnaB-like helicase C terminal domain ChlI PF13541.6 ABK69709.1 - 2.5e-07 30.6 0.1 7.9e-07 28.9 0.0 1.9 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_30 PF13604.6 ABK69709.1 - 9.6e-05 22.2 2.1 0.00018 21.3 2.1 1.4 1 0 0 1 1 1 1 AAA domain Rad51 PF08423.11 ABK69709.1 - 0.00016 21.1 0.3 0.001 18.4 0.3 2.1 1 1 0 1 1 1 1 Rad51 AAA_16 PF13191.6 ABK69709.1 - 0.00036 21.0 0.1 0.00058 20.3 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 ABK69709.1 - 0.0004 20.8 0.0 0.00065 20.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 ABK69709.1 - 0.0022 17.9 0.0 0.0036 17.3 0.0 1.3 1 0 0 1 1 1 1 NACHT domain RecA PF00154.21 ABK69709.1 - 0.0025 17.4 0.4 0.0064 16.0 0.2 1.5 1 1 0 1 1 1 1 recA bacterial DNA recombination protein Lon_C PF05362.13 ABK69709.1 - 0.0051 16.4 0.3 0.0051 16.4 0.3 1.9 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain AAA_24 PF13479.6 ABK69709.1 - 0.0056 16.4 0.0 0.014 15.2 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_29 PF13555.6 ABK69709.1 - 0.0087 15.8 0.4 0.025 14.3 0.1 1.9 2 0 0 2 2 1 1 P-loop containing region of AAA domain NTPase_1 PF03266.15 ABK69709.1 - 0.024 14.6 0.0 0.18 11.7 0.0 2.1 1 1 1 2 2 2 0 NTPase AAA_22 PF13401.6 ABK69709.1 - 0.034 14.4 0.0 0.068 13.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain MCM PF00493.23 ABK69709.1 - 0.047 12.8 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain Glyco_hydro2_C5 PF18565.1 ABK69709.1 - 0.053 13.4 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Glycoside hydrolase family 2 C-terminal domain 5 RsgA_GTPase PF03193.16 ABK69709.1 - 0.055 13.4 0.0 0.09 12.7 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase PAXNEB PF05625.11 ABK69709.1 - 0.071 12.2 1.0 0.11 11.6 0.6 1.4 2 0 0 2 2 2 0 PAXNEB protein DUF2075 PF09848.9 ABK69709.1 - 0.1 11.8 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 ABK69709.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 ABK69709.1 - 0.13 12.8 0.0 0.21 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ABK69709.1 - 0.17 12.4 0.0 0.28 11.7 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_11 PF13086.6 ABK69709.1 - 0.17 11.6 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain L_biotic_typeA PF04604.13 ABK69709.1 - 0.21 11.5 0.4 28 4.7 0.1 2.4 2 0 0 2 2 2 0 Type-A lantibiotic BPD_transp_1 PF00528.22 ABK69710.1 - 3.3e-22 79.1 14.6 3.3e-22 79.1 14.6 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Romo1 PF10247.9 ABK69710.1 - 0.15 12.5 0.6 0.15 12.5 0.6 2.4 3 0 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 HD PF01966.22 ABK69711.1 - 0.00018 21.7 0.3 0.0003 21.0 0.3 1.4 1 1 0 1 1 1 1 HD domain PALP PF00291.25 ABK69712.1 - 7e-44 150.4 0.0 8.4e-44 150.1 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Na_Ala_symp PF01235.17 ABK69712.1 - 0.062 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Sodium:alanine symporter family LYTB PF02401.18 ABK69712.1 - 0.09 12.0 0.0 0.24 10.6 0.0 1.6 2 0 0 2 2 2 0 LytB protein Nitroreductase PF00881.24 ABK69714.1 - 3.7e-21 75.9 1.7 3.9e-20 72.6 1.7 2.0 1 1 0 1 1 1 1 Nitroreductase family ACP_syn_III PF08545.10 ABK69716.1 - 0.002 17.9 0.1 0.0053 16.6 0.1 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 ABK69716.1 - 0.022 14.9 0.0 0.081 13.1 0.0 2.0 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal adh_short PF00106.25 ABK69718.1 - 2.4e-36 125.1 0.1 3.1e-36 124.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK69718.1 - 2.4e-24 86.2 1.3 3.1e-24 85.8 1.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 ABK69718.1 - 2.7e-07 30.6 1.3 4.7e-07 29.9 1.2 1.8 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 ABK69718.1 - 9.3e-07 28.9 0.2 1.2e-05 25.3 0.2 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK69718.1 - 6.2e-05 22.6 0.1 0.00016 21.2 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ABK69718.1 - 0.0008 18.6 0.1 0.0015 17.7 0.1 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Head_binding PF09008.10 ABK69718.1 - 0.026 14.8 0.0 0.08 13.2 0.0 1.7 2 0 0 2 2 2 0 Head binding DUF1776 PF08643.10 ABK69718.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DIOX_N PF14226.6 ABK69719.1 - 3.2e-26 92.4 0.0 4.4e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ABK69719.1 - 2.9e-13 50.2 0.0 6e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Bac_luciferase PF00296.20 ABK69720.1 - 3.6e-25 89.0 0.1 8.2e-24 84.6 0.1 2.0 1 1 0 1 1 1 1 Luciferase-like monooxygenase NMO PF03060.15 ABK69721.1 - 8.9e-104 347.4 6.7 1.1e-101 340.5 6.7 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 ABK69721.1 - 3.7e-11 42.6 5.5 3.7e-11 42.6 5.5 1.6 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 ABK69721.1 - 1.9e-06 27.2 6.6 2e-06 27.1 4.9 1.7 1 1 1 2 2 2 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 ABK69721.1 - 0.11 11.7 0.5 0.17 11.1 0.5 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase APH PF01636.23 ABK69722.1 - 3e-26 92.8 7.4 4.2e-26 92.3 7.4 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ABK69722.1 - 0.00054 19.6 0.0 0.0048 16.5 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 ABK69722.1 - 0.007 15.6 0.6 0.15 11.3 0.0 2.7 2 1 0 2 2 2 1 Fructosamine kinase Sua5_yciO_yrdC PF01300.18 ABK69723.1 - 1.2e-43 148.7 0.0 1.4e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Telomere recombination ABATE PF07336.11 ABK69723.1 - 0.47 11.1 4.4 0.26 12.0 0.6 2.2 1 1 1 2 2 2 0 Putative stress-induced transcription regulator PhyH PF05721.13 ABK69724.1 - 2.8e-05 24.5 0.2 5.5e-05 23.5 0.1 1.6 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) NusG PF02357.19 ABK69725.1 - 3.2e-25 88.4 0.0 6.1e-25 87.6 0.0 1.5 1 0 0 1 1 1 1 Transcription termination factor nusG KOW PF00467.29 ABK69725.1 - 0.079 12.9 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 KOW motif ThiC_Rad_SAM PF01964.18 ABK69726.1 - 1.8e-197 656.2 0.0 2.1e-197 656.0 0.0 1.0 1 0 0 1 1 1 1 Radical SAM ThiC family ThiC-associated PF13667.6 ABK69726.1 - 1.4e-09 37.6 0.2 5e-09 35.9 0.2 2.0 1 1 0 1 1 1 1 ThiC-associated domain THF_DHG_CYH_C PF02882.19 ABK69727.1 - 1.8e-61 206.1 1.1 7.3e-61 204.2 1.3 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 ABK69727.1 - 1.5e-34 118.7 0.0 2.1e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AlaDh_PNT_C PF01262.21 ABK69727.1 - 0.12 11.6 4.2 0.25 10.6 0.3 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain V-ATPase_G_2 PF16999.5 ABK69728.1 - 2.8e-05 24.5 32.6 0.02 15.3 19.0 3.6 1 1 2 3 3 3 2 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 ABK69728.1 - 0.00011 22.3 33.7 1 9.4 1.3 3.9 1 1 3 4 4 4 4 ATP synthase B/B' CF(0) DivIVA PF05103.13 ABK69728.1 - 0.00015 21.9 21.8 0.012 15.6 5.5 3.5 1 1 2 3 3 3 2 DivIVA protein HrpE PF06188.12 ABK69728.1 - 0.0015 18.4 14.9 0.27 11.1 8.9 2.8 1 1 1 2 2 2 2 HrpE/YscL/FliH and V-type ATPase subunit E DUF883 PF05957.13 ABK69728.1 - 0.78 10.4 25.5 0.051 14.2 8.5 3.5 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF883) V-ATPase_G PF03179.15 ABK69728.1 - 2.9 8.5 23.3 15 6.2 16.1 3.2 1 1 3 4 4 4 0 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.8 ABK69728.1 - 2.9 7.2 25.0 8.1 5.8 0.8 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF3552) Rotamase PF00639.21 ABK69728.1 - 3.9 8.5 6.4 12 6.9 6.4 2.2 1 1 0 1 1 1 0 PPIC-type PPIASE domain MFS_1 PF07690.16 ABK69729.1 - 8.6e-36 123.6 44.4 7e-21 74.5 20.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK69729.1 - 1.7e-28 99.7 26.8 2.3e-25 89.4 6.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 ABK69729.1 - 7.8e-06 24.7 29.0 0.00014 20.6 8.0 3.2 2 1 1 3 3 3 3 MFS/sugar transport protein FliP PF00813.20 ABK69729.1 - 0.045 13.6 1.7 3.1 7.7 0.5 2.4 2 0 0 2 2 2 0 FliP family Sugar-bind PF04198.13 ABK69731.1 - 7.6e-60 202.2 0.5 1e-59 201.8 0.5 1.1 1 0 0 1 1 1 1 Putative sugar-binding domain HTH_23 PF13384.6 ABK69731.1 - 1.5e-06 27.8 0.8 1e-05 25.1 0.2 2.5 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 ABK69731.1 - 3.6e-06 26.6 0.5 7.8e-06 25.5 0.5 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 MarR_2 PF12802.7 ABK69731.1 - 5e-06 26.3 2.6 1.5e-05 24.8 0.2 2.9 2 0 0 2 2 2 1 MarR family Sigma70_r4 PF04545.16 ABK69731.1 - 1.1e-05 24.8 0.3 3e-05 23.4 0.3 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_Crp_2 PF13545.6 ABK69731.1 - 0.00012 22.0 1.8 0.0033 17.4 0.1 3.2 3 0 0 3 3 3 1 Crp-like helix-turn-helix domain HTH_38 PF13936.6 ABK69731.1 - 0.00032 20.4 0.1 0.00096 18.9 0.1 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain Crp PF00325.20 ABK69731.1 - 0.00052 19.6 0.4 0.74 9.5 0.1 2.5 2 0 0 2 2 2 2 Bacterial regulatory proteins, crp family Sigma70_ECF PF07638.11 ABK69731.1 - 0.0015 18.5 0.1 0.003 17.5 0.1 1.5 1 0 0 1 1 1 1 ECF sigma factor MarR PF01047.22 ABK69731.1 - 0.0019 18.1 0.0 0.004 17.0 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_28 PF13518.6 ABK69731.1 - 0.0028 17.7 0.7 0.0099 16.0 0.1 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 ABK69731.1 - 0.008 16.2 0.6 0.026 14.6 0.1 2.1 2 0 0 2 2 2 1 Winged helix-turn helix Fe_dep_repress PF01325.19 ABK69731.1 - 0.012 15.8 0.2 0.035 14.3 0.1 1.9 2 0 0 2 2 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_IclR PF09339.10 ABK69731.1 - 0.018 14.8 0.0 0.018 14.8 0.0 3.3 4 0 0 4 4 4 0 IclR helix-turn-helix domain HTH_40 PF14493.6 ABK69731.1 - 0.022 15.2 0.0 0.06 13.8 0.0 1.9 2 0 0 2 2 1 0 Helix-turn-helix domain HTH_31 PF13560.6 ABK69731.1 - 0.049 14.0 0.3 0.049 14.0 0.3 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_24 PF13412.6 ABK69731.1 - 0.05 13.2 0.3 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding TrmB PF01978.19 ABK69731.1 - 0.13 12.1 0.0 0.38 10.7 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_3 PF01381.22 ABK69731.1 - 0.15 12.2 0.0 0.41 10.7 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix GerE PF00196.19 ABK69731.1 - 0.15 11.6 0.0 0.35 10.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_46 PF15977.5 ABK69731.1 - 0.17 11.9 0.0 0.52 10.4 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA binding Peptidase_C26 PF07722.13 ABK69732.1 - 1e-36 126.7 0.0 1.2e-36 126.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase C26 GATase PF00117.28 ABK69732.1 - 3.3e-15 56.4 0.0 3e-14 53.2 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase class-I FdsD PF11390.8 ABK69733.1 - 6.7e-20 71.2 0.3 8.3e-20 70.9 0.3 1.1 1 0 0 1 1 1 1 NADH-dependant formate dehydrogenase delta subunit FdsD Abhydrolase_1 PF00561.20 ABK69734.1 - 7.2e-21 75.0 1.2 1.5e-19 70.7 1.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK69734.1 - 1.6e-16 61.6 10.5 1.9e-16 61.3 10.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK69734.1 - 5e-08 32.5 0.3 1.2e-07 31.2 0.3 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FdhD-NarQ PF02634.15 ABK69735.1 - 5.1e-84 281.7 0.0 5.9e-84 281.5 0.0 1.0 1 0 0 1 1 1 1 FdhD/NarQ family DDE_Tnp_1_4 PF13701.6 ABK69736.1 - 4.5e-29 101.0 0.0 7e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain group 1 DDE_Tnp_1 PF01609.21 ABK69736.1 - 6.4e-06 26.0 0.0 1.2e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 Transposase DDE domain Aconitase PF00330.20 ABK69737.1 - 3.1e-89 300.1 0.5 2.2e-87 294.0 0.5 2.3 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ABK69737.1 - 1.1e-21 77.5 0.0 1.9e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.13 ABK69737.1 - 0.0065 16.1 0.0 0.083 12.5 0.0 2.4 3 0 0 3 3 3 1 Aconitate hydratase 2 N-terminus Ribosomal_S20p PF01649.18 ABK69738.1 - 8.8e-30 103.2 8.9 9.7e-30 103.1 8.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S20 DUF4878 PF12870.7 ABK69738.1 - 0.011 16.0 0.1 0.013 15.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4878) SMBP PF16785.5 ABK69738.1 - 0.018 15.2 0.4 0.02 15.1 0.4 1.1 1 0 0 1 1 1 0 Small metal-binding protein UPF0054 PF02130.17 ABK69739.1 - 2.5e-37 127.5 0.0 3.2e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 COX3 PF00510.18 ABK69740.1 - 3.7e-28 99.1 12.8 4.4e-28 98.8 12.8 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III MlaD PF02470.20 ABK69741.1 - 3.5e-19 68.9 0.4 6.5e-19 68.0 0.4 1.5 1 0 0 1 1 1 1 MlaD protein Mce4_CUP1 PF11887.8 ABK69741.1 - 0.00082 18.9 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative NAD_binding_10 PF13460.6 ABK69742.1 - 2.5e-12 47.1 6.0 2.5e-11 43.8 6.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ABK69742.1 - 1.5e-07 31.2 0.9 1.9e-05 24.4 0.9 2.2 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 ABK69742.1 - 2.1e-05 24.1 0.3 6e-05 22.6 0.1 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ABK69742.1 - 0.00032 19.9 1.5 0.0022 17.1 0.2 2.4 2 1 0 2 2 2 1 RmlD substrate binding domain Semialdhyde_dh PF01118.24 ABK69742.1 - 0.00098 19.6 0.4 0.0061 17.0 0.4 2.2 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 ABK69742.1 - 0.24 11.6 2.3 0.68 10.1 1.2 2.3 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus TetR_C_33 PF13305.6 ABK69743.1 - 4.3e-14 53.1 3.9 4.3e-14 53.1 3.9 1.8 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK69743.1 - 1.1e-11 44.3 0.1 1.9e-11 43.6 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_15 PF17918.1 ABK69743.1 - 0.0017 19.1 3.4 0.0017 19.1 3.4 2.9 3 1 0 3 3 3 1 Tetracyclin repressor-like, C-terminal domain TPR_14 PF13428.6 ABK69743.1 - 3.1 8.9 12.8 0.68 10.9 0.7 3.6 2 1 0 3 3 3 0 Tetratricopeptide repeat Esterase PF00756.20 ABK69744.1 - 5.4e-58 196.6 0.5 6.3e-58 196.4 0.5 1.0 1 0 0 1 1 1 1 Putative esterase LysR_substrate PF03466.20 ABK69745.1 - 5.9e-39 133.6 8.7 8.4e-39 133.1 8.7 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 ABK69745.1 - 8.8e-17 60.8 0.4 1.9e-16 59.7 0.4 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family SBP_bac_11 PF13531.6 ABK69745.1 - 0.0033 17.2 0.2 0.025 14.3 0.2 2.2 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein TetR_C_16 PF17920.1 ABK69747.1 - 3.9e-27 94.6 1.9 3.9e-27 94.6 1.9 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK69747.1 - 3.3e-16 58.8 0.6 5.4e-16 58.1 0.6 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 ABK69747.1 - 0.00024 21.4 10.4 0.00051 20.3 3.2 2.6 1 1 0 2 2 2 2 Tetracyclin repressor-like, C-terminal domain DUF2760 PF10816.8 ABK69747.1 - 0.092 12.6 0.1 8.1 6.3 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF2760) cobW PF02492.19 ABK69748.1 - 3.9e-26 91.7 0.0 4.8e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 ABK69748.1 - 0.0019 17.7 0.0 0.011 15.1 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 ABK69748.1 - 0.011 15.6 0.0 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase MobB PF03205.14 ABK69748.1 - 0.22 11.4 0.0 0.22 11.4 0.0 2.0 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B malic PF00390.19 ABK69749.1 - 3.7e-27 95.3 0.2 9.3e-20 71.2 0.1 2.6 1 1 1 2 2 2 2 Malic enzyme, N-terminal domain Malic_M PF03949.15 ABK69749.1 - 2.1e-22 79.6 1.7 7e-21 74.7 1.7 2.6 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain Ldh_1_N PF00056.23 ABK69749.1 - 0.0091 16.1 3.0 0.017 15.2 0.2 2.6 2 1 1 3 3 3 1 lactate/malate dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 ABK69749.1 - 0.011 15.0 1.8 0.021 14.1 1.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ELFV_dehydrog PF00208.21 ABK69749.1 - 0.022 14.5 1.3 0.03 14.0 0.2 1.8 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_8 PF13450.6 ABK69749.1 - 0.03 14.6 0.1 0.063 13.5 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ThiF PF00899.21 ABK69749.1 - 0.04 13.3 2.0 0.087 12.2 2.0 1.5 1 0 0 1 1 1 0 ThiF family Metallophos PF00149.28 ABK69750.1 - 4.2e-14 53.5 0.0 9e-14 52.5 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ABK69750.1 - 0.0003 21.0 0.0 0.015 15.5 0.0 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain PEX-1N PF09262.11 ABK69750.1 - 0.17 12.3 0.0 12 6.4 0.0 2.3 2 0 0 2 2 2 0 Peroxisome biogenesis factor 1, N-terminal HupF_HypC PF01455.18 ABK69753.1 - 9.3e-05 22.5 0.5 0.00023 21.2 0.5 1.7 1 0 0 1 1 1 1 HupF/HypC family Acyl-CoA_dh_N PF02771.16 ABK69754.1 - 1.1e-29 103.4 0.3 3e-29 102.0 0.1 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 ABK69754.1 - 1.2e-29 103.4 0.1 1.8e-29 102.9 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK69754.1 - 1e-25 89.7 0.1 1.8e-25 88.9 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ABK69754.1 - 2.7e-08 34.2 0.0 4.4e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain TetR_N PF00440.23 ABK69755.1 - 6.1e-05 22.7 0.1 0.00029 20.6 0.0 2.3 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_1 PF00126.27 ABK69755.1 - 0.0013 18.6 0.1 0.0056 16.6 0.1 2.2 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_22 PF13309.6 ABK69755.1 - 0.063 13.4 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 HTH domain HTH_10 PF04967.12 ABK69755.1 - 0.1 12.5 0.3 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 HTH DNA binding domain adh_short PF00106.25 ABK69756.1 - 1.8e-30 105.9 0.1 2.6e-30 105.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK69756.1 - 1.5e-21 77.1 1.4 2e-21 76.6 1.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ABK69756.1 - 2.8e-08 33.5 0.4 2.1e-07 30.6 0.2 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 ABK69756.1 - 5.2e-08 33.0 1.6 2.1e-07 31.0 1.4 2.0 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ABK69756.1 - 8.1e-08 32.4 1.1 1.7e-07 31.3 1.1 1.6 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 ABK69756.1 - 8.5e-07 28.4 0.0 1.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 ABK69756.1 - 0.0045 16.2 0.3 0.037 13.2 0.3 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 ABK69756.1 - 0.085 12.0 0.9 2.3 7.3 0.0 2.7 1 1 1 2 2 2 0 Male sterility protein Herpes_U55 PF06501.11 ABK69756.1 - 0.12 11.1 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Human herpesvirus U55 protein 3Beta_HSD PF01073.19 ABK69756.1 - 0.17 10.8 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 4HBT_3 PF13622.6 ABK69757.1 - 7.9e-33 114.7 2.4 9e-33 114.6 2.4 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Peripla_BP_3 PF13377.6 ABK69758.1 - 9.7e-28 97.6 1.3 9.7e-28 97.6 1.3 1.9 2 1 1 3 3 3 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 ABK69758.1 - 9.5e-23 81.0 0.0 1.3e-22 80.6 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 ABK69758.1 - 8.2e-20 70.3 1.5 1.9e-19 69.2 1.5 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 ABK69758.1 - 9.7e-11 41.7 0.0 1.6e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein domain HTH_31 PF13560.6 ABK69758.1 - 0.0056 17.0 0.3 0.0056 17.0 0.3 2.0 2 0 0 2 2 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 ABK69758.1 - 0.0063 15.9 2.0 0.01 15.3 0.3 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_3 PF01381.22 ABK69758.1 - 0.014 15.4 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix HTH_38 PF13936.6 ABK69758.1 - 0.043 13.6 0.0 0.097 12.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 ABK69758.1 - 0.082 12.5 0.1 0.21 11.2 0.1 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding TetR_N PF00440.23 ABK69758.1 - 0.099 12.4 0.1 0.099 12.4 0.1 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family HTH_23 PF13384.6 ABK69758.1 - 0.1 12.4 0.1 0.31 10.9 0.1 1.8 1 0 0 1 1 1 0 Homeodomain-like domain Sigma54_DBD PF04552.13 ABK69758.1 - 0.14 11.8 0.2 0.33 10.6 0.1 1.7 2 0 0 2 2 2 0 Sigma-54, DNA binding domain HTH_26 PF13443.6 ABK69758.1 - 0.18 12.2 0.0 0.38 11.2 0.0 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Trp_repressor PF01371.19 ABK69758.1 - 0.21 11.7 0.1 0.37 10.9 0.1 1.4 1 0 0 1 1 1 0 Trp repressor protein GATase PF00117.28 ABK69759.1 - 1.9e-51 174.5 0.0 2.4e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ABK69759.1 - 2e-15 57.1 0.2 7e-15 55.4 0.2 1.9 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 ABK69759.1 - 0.15 11.8 0.1 0.25 11.1 0.1 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family Sulfotransfer_3 PF13469.6 ABK69760.1 - 9.5e-62 209.2 1.4 1.4e-61 208.6 1.4 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 ABK69760.1 - 4.9e-09 36.0 0.0 6.3e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_4 PF17784.1 ABK69760.1 - 6.3e-05 22.9 0.2 0.0088 15.9 0.1 2.3 2 0 0 2 2 2 2 Sulfotransferase domain CDPS PF16715.5 ABK69760.1 - 0.0056 16.4 0.1 0.81 9.3 0.0 2.9 3 0 0 3 3 3 1 Cyclodipeptide synthase Sulphotransf PF09037.10 ABK69760.1 - 0.02 14.4 0.0 0.34 10.4 0.0 2.6 2 1 1 3 3 3 0 Stf0 sulphotransferase dUTPase PF00692.19 ABK69761.1 - 4e-31 107.4 0.0 4.8e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 dUTPase Na_Ala_symp PF01235.17 ABK69762.1 - 4.4e-150 500.4 33.2 5.6e-150 500.0 33.2 1.1 1 0 0 1 1 1 1 Sodium:alanine symporter family SieB PF14163.6 ABK69762.1 - 0.75 9.3 2.7 2.4 7.6 2.7 1.9 1 0 0 1 1 1 0 Super-infection exclusion protein B APH PF01636.23 ABK69763.1 - 9.3e-26 91.2 1.9 1.4e-25 90.6 1.9 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ABK69763.1 - 0.009 15.6 0.0 0.04 13.5 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.20 ABK69763.1 - 0.025 13.9 0.0 0.033 13.5 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase RecO_C PF02565.15 ABK69764.1 - 9.3e-32 110.0 0.4 1.2e-31 109.6 0.4 1.2 1 0 0 1 1 1 1 Recombination protein O C terminal RecO_N PF11967.8 ABK69764.1 - 3.3e-28 97.5 0.1 8.1e-28 96.2 0.0 1.7 2 0 0 2 2 2 1 Recombination protein O N terminal RecO_N_2 PF13114.6 ABK69764.1 - 0.0097 15.6 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 RecO N terminal DUF3724 PF12521.8 ABK69764.1 - 0.11 12.5 0.1 0.26 11.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3724) PTS-HPr PF00381.19 ABK69765.1 - 2.4e-19 69.4 0.6 2.6e-19 69.2 0.6 1.0 1 0 0 1 1 1 1 PTS HPr component phosphorylation site CoA_transf_3 PF02515.17 ABK69766.1 - 2.7e-64 217.6 0.2 3.1e-64 217.4 0.2 1.0 1 0 0 1 1 1 1 CoA-transferase family III Cys_Met_Meta_PP PF01053.20 ABK69767.1 - 7e-143 475.8 0.0 7.8e-143 475.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 ABK69767.1 - 2.4e-10 40.3 0.1 8.8e-10 38.4 0.1 1.9 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 ABK69767.1 - 2.3e-07 29.7 0.0 9.3e-07 27.7 0.0 1.8 1 1 0 1 1 1 1 Methionine gamma-lyase Aminotran_1_2 PF00155.21 ABK69767.1 - 1.8e-05 24.1 0.0 2.9e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 ABK69767.1 - 0.00016 20.8 0.0 0.00023 20.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 ABK69767.1 - 0.0015 17.9 0.0 0.0037 16.6 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase FCD PF07729.12 ABK69769.1 - 8.2e-20 71.5 12.8 8.2e-20 71.5 12.8 1.6 2 0 0 2 2 2 1 FCD domain GntR PF00392.21 ABK69769.1 - 2.7e-15 55.7 0.3 7.4e-15 54.3 0.3 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 ABK69769.1 - 0.036 13.6 0.0 0.097 12.3 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 ABK69769.1 - 0.043 13.7 0.7 0.043 13.7 0.7 2.7 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain HTH_Crp_2 PF13545.6 ABK69769.1 - 0.077 13.0 0.7 0.19 11.7 0.2 1.9 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Fe_dep_repress PF01325.19 ABK69769.1 - 0.079 13.2 0.0 0.38 11.0 0.0 2.1 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain AA_permease PF00324.21 ABK69770.1 - 1.6e-103 346.9 47.6 2e-103 346.5 47.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ABK69770.1 - 3.1e-39 135.0 52.9 3.8e-39 134.7 52.9 1.1 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.13 ABK69770.1 - 7.6e-08 31.5 15.3 7.6e-08 31.5 15.3 2.2 2 0 0 2 2 2 1 Spore germination protein Lon_C PF05362.13 ABK69771.1 - 1.1e-85 286.3 0.3 1.9e-85 285.5 0.3 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 ABK69771.1 - 2.6e-20 73.2 0.0 7.2e-20 71.8 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 ABK69771.1 - 1.3e-18 67.6 0.0 2.1e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain ChlI PF13541.6 ABK69771.1 - 2.7e-09 36.9 0.1 4.9e-09 36.1 0.1 1.4 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 ABK69771.1 - 4.9e-08 33.1 0.0 9.3e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 ABK69771.1 - 2.2e-05 24.7 0.0 4.4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 ABK69771.1 - 0.0001 22.7 2.0 0.0002 21.8 0.6 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_3 PF07726.11 ABK69771.1 - 0.00085 19.2 0.0 0.0021 17.9 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ABK69771.1 - 0.0012 19.1 0.1 0.064 13.5 0.0 3.1 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 ABK69771.1 - 0.011 15.7 0.1 0.047 13.6 0.0 2.2 1 1 1 2 2 2 0 NTPase AAA_18 PF13238.6 ABK69771.1 - 0.016 15.7 0.0 0.053 14.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_PrkA PF08298.11 ABK69771.1 - 0.019 13.9 0.0 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain AAA_33 PF13671.6 ABK69771.1 - 0.025 14.7 0.9 0.056 13.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ABK69771.1 - 0.028 14.0 0.1 0.17 11.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 ABK69771.1 - 0.03 14.1 0.0 0.073 12.8 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 ABK69771.1 - 0.079 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 ABK69771.1 - 0.079 13.0 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ABK69771.1 - 0.09 12.5 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 ABK69771.1 - 0.17 11.8 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase GGDEF_2 PF17853.1 ABK69771.1 - 1.1 9.6 5.9 0.34 11.2 0.5 3.0 4 0 0 4 4 2 0 GGDEF-like domain ICMT PF04140.14 ABK69772.1 - 4.3e-24 84.7 0.0 6.7e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 ABK69772.1 - 5e-05 23.7 0.0 7.3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Phospholipid methyltransferase PsaM PF07465.13 ABK69772.1 - 2.3 8.0 5.7 4.7 7.0 0.3 2.6 2 0 0 2 2 2 0 Photosystem I protein M (PsaM) MIase PF02426.16 ABK69773.1 - 2.7e-30 104.4 0.0 3e-30 104.2 0.0 1.0 1 0 0 1 1 1 1 Muconolactone delta-isomerase FAD_syn PF06574.12 ABK69774.1 - 3e-52 176.7 0.3 5.2e-52 175.9 0.3 1.3 1 0 0 1 1 1 1 FAD synthetase Flavokinase PF01687.17 ABK69774.1 - 6.4e-35 119.8 0.0 1.3e-34 118.8 0.0 1.5 1 0 0 1 1 1 1 Riboflavin kinase CTP_transf_like PF01467.26 ABK69774.1 - 0.00011 22.4 0.2 0.00058 20.1 0.1 2.2 2 1 0 2 2 2 1 Cytidylyltransferase-like ATP-sulfurylase PF01747.17 ABK69774.1 - 0.038 13.5 0.0 3.1 7.2 0.0 2.2 2 0 0 2 2 2 0 ATP-sulfurylase Response_reg PF00072.24 ABK69775.1 - 6.8e-30 103.5 0.1 1.2e-29 102.7 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 ABK69775.1 - 1e-26 92.8 0.7 4.7e-26 90.7 0.1 2.1 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal B12-binding PF02310.19 ABK69775.1 - 0.11 12.5 0.0 0.27 11.3 0.0 1.7 1 1 0 1 1 1 0 B12 binding domain Aldedh PF00171.22 ABK69777.1 - 7.3e-161 535.7 0.0 8.3e-161 535.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aminotran_5 PF00266.19 ABK69778.1 - 1.4e-32 113.1 0.0 1.5e-31 109.7 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 ABK69778.1 - 1.2e-05 24.0 0.0 1.9e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 ABK69778.1 - 0.0025 17.1 0.0 0.0079 15.4 0.0 1.9 2 1 0 2 2 2 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 ABK69778.1 - 0.0082 15.5 0.0 0.021 14.1 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family PAD_porph PF04371.15 ABK69779.1 - 2.2e-97 326.2 0.0 2.5e-97 326.0 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Amidinotransf PF02274.17 ABK69779.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Amidinotransferase DUF4148 PF13663.6 ABK69779.1 - 0.14 12.4 0.1 0.42 10.8 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) AIRS_C PF02769.22 ABK69780.1 - 3.1e-35 121.6 0.2 5.3e-35 120.8 0.2 1.4 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 ABK69780.1 - 5.3e-16 59.1 0.4 1.1e-15 58.0 0.4 1.6 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain FAD_binding_4 PF01565.23 ABK69780.1 - 0.018 14.8 0.4 0.16 11.7 0.1 2.4 2 0 0 2 2 2 0 FAD binding domain Flavin_Reduct PF01613.18 ABK69782.1 - 6e-25 88.1 0.5 7.8e-25 87.7 0.5 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Putative_PNPOx PF01243.20 ABK69782.1 - 0.12 12.6 0.0 0.28 11.4 0.0 1.6 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase LCM PF04072.14 ABK69783.1 - 1.3e-63 214.4 0.2 1.7e-63 213.9 0.2 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase AP_endonuc_2 PF01261.24 ABK69783.1 - 0.011 15.2 0.3 0.027 13.9 0.3 1.8 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel Bac_luciferase PF00296.20 ABK69784.1 - 2.5e-16 60.0 4.2 1.2e-12 47.9 0.1 2.3 1 1 1 2 2 2 2 Luciferase-like monooxygenase Aldedh PF00171.22 ABK69785.1 - 3e-126 421.7 0.2 3.4e-126 421.5 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LysR_substrate PF03466.20 ABK69786.1 - 1.5e-38 132.2 6.7 2.6e-38 131.5 6.7 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 ABK69786.1 - 6.7e-23 80.4 0.2 1.4e-22 79.4 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_24 PF13412.6 ABK69786.1 - 0.15 11.7 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 ABK69787.1 - 3.8e-15 55.5 1.2 8e-15 54.5 1.2 1.6 1 0 0 1 1 1 1 MarR family MarR PF01047.22 ABK69787.1 - 9.7e-13 47.8 0.5 2.9e-12 46.3 0.5 1.8 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 ABK69787.1 - 6.7e-08 32.9 0.8 1.2e-07 32.1 0.5 1.6 1 1 0 1 1 1 1 Winged helix DNA-binding domain HTH_24 PF13412.6 ABK69787.1 - 0.0017 17.8 0.2 0.0035 16.9 0.2 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding SMC_ScpB PF04079.16 ABK69787.1 - 0.0019 17.9 0.2 0.0026 17.4 0.2 1.2 1 0 0 1 1 1 1 Segregation and condensation complex subunit ScpB HxlR PF01638.17 ABK69787.1 - 0.0048 16.7 0.6 0.028 14.2 0.1 2.1 1 1 1 2 2 2 1 HxlR-like helix-turn-helix GntR PF00392.21 ABK69787.1 - 0.005 16.5 1.4 0.014 15.1 0.1 2.4 3 0 0 3 3 3 1 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 ABK69787.1 - 0.026 14.6 1.7 0.046 13.8 0.2 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain TrmB PF01978.19 ABK69787.1 - 0.045 13.6 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 ABK69787.1 - 0.051 13.5 1.4 0.09 12.8 0.7 1.8 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain PadR PF03551.14 ABK69787.1 - 0.096 12.7 0.1 0.35 10.9 0.1 1.9 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family DUF1490 PF07371.12 ABK69788.1 - 2e-42 143.2 11.9 2.2e-42 143.0 11.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1490) Dehydratase_MU PF02288.15 ABK69789.1 - 2.7e-34 117.3 0.0 4.1e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 Dehydratase medium subunit Thiolase_C PF02803.18 ABK69790.1 - 0.00021 20.9 0.1 0.00044 19.9 0.1 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain DctQ PF04290.12 ABK69791.1 - 2.8e-24 85.5 9.9 2.8e-24 85.5 9.9 1.4 2 0 0 2 2 2 1 Tripartite ATP-independent periplasmic transporters, DctQ component Abhydrolase_9_N PF15420.6 ABK69791.1 - 0.067 13.2 11.2 0.09 12.8 11.2 1.1 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus GPI2 PF06432.11 ABK69791.1 - 0.45 9.9 3.1 1.7 8.0 3.0 1.7 1 1 1 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase MARVEL PF01284.23 ABK69791.1 - 3 7.9 9.2 15 5.6 8.8 2.1 1 1 0 1 1 1 0 Membrane-associating domain MFS_1 PF07690.16 ABK69792.1 - 2.3e-29 102.4 79.4 1.9e-24 86.3 44.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK69792.1 - 6.9e-28 97.7 27.8 1.4e-27 96.7 27.8 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter ATG22 PF11700.8 ABK69792.1 - 0.016 13.9 9.1 0.13 10.9 1.5 2.8 2 1 0 2 2 2 0 Vacuole effluxer Atg22 like MarR_2 PF12802.7 ABK69793.1 - 1.6e-15 56.7 0.4 6.6e-15 54.7 0.4 2.1 1 0 0 1 1 1 1 MarR family Acetyltransf_1 PF00583.25 ABK69793.1 - 1.4e-14 54.3 0.1 3.9e-14 52.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family MarR PF01047.22 ABK69793.1 - 7.6e-11 41.8 0.0 3.5e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 ABK69793.1 - 7.1e-10 39.2 0.1 1.7e-09 38.0 0.1 1.7 1 0 0 1 1 1 1 Winged helix DNA-binding domain Acetyltransf_7 PF13508.7 ABK69793.1 - 1.6e-09 38.1 0.0 3.2e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ABK69793.1 - 7.1e-09 35.7 0.0 1.1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HTH_24 PF13412.6 ABK69793.1 - 2e-05 24.0 0.5 5.7e-05 22.6 0.1 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding FR47 PF08445.10 ABK69793.1 - 0.00054 19.9 0.1 0.026 14.5 0.0 2.4 2 0 0 2 2 2 1 FR47-like protein PadR PF03551.14 ABK69793.1 - 0.001 19.0 0.0 0.0023 17.9 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_IclR PF09339.10 ABK69793.1 - 0.002 17.9 0.3 0.014 15.2 0.0 2.4 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_34 PF13601.6 ABK69793.1 - 0.0029 17.8 0.0 0.033 14.4 0.0 2.2 2 0 0 2 2 2 1 Winged helix DNA-binding domain TrmB PF01978.19 ABK69793.1 - 0.0065 16.3 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 ABK69793.1 - 0.022 15.1 0.0 0.057 13.8 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator LexA_DNA_bind PF01726.16 ABK69793.1 - 0.031 14.1 0.1 0.56 10.0 0.0 2.5 3 0 0 3 3 2 0 LexA DNA binding domain HTH_Crp_2 PF13545.6 ABK69793.1 - 0.032 14.2 1.8 0.049 13.6 0.2 2.2 2 1 0 2 2 1 0 Crp-like helix-turn-helix domain HTH_32 PF13565.6 ABK69793.1 - 0.036 14.7 0.9 0.17 12.5 0.9 2.2 1 1 0 1 1 1 0 Homeodomain-like domain TetR_N PF00440.23 ABK69793.1 - 0.047 13.5 0.1 1.3 8.9 0.0 3.0 3 0 0 3 3 3 0 Bacterial regulatory proteins, tetR family GntR PF00392.21 ABK69793.1 - 0.48 10.1 0.0 0.48 10.1 0.0 2.3 3 0 0 3 3 3 0 Bacterial regulatory proteins, gntR family Aminotran_1_2 PF00155.21 ABK69794.1 - 9.3e-62 209.3 0.0 1.1e-61 209.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 ABK69794.1 - 1.2e-07 31.0 0.0 1.7e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 ABK69794.1 - 4.6e-05 22.1 0.0 7.1e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 ABK69794.1 - 0.00016 21.1 0.5 0.00025 20.5 0.5 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 ABK69794.1 - 0.0075 15.6 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_3 PF00202.21 ABK69794.1 - 0.21 10.2 0.0 0.36 9.4 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-III adh_short_C2 PF13561.6 ABK69795.1 - 3.3e-48 164.3 1.4 5.9e-48 163.5 1.4 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK69795.1 - 8.5e-43 146.1 0.4 1e-42 145.8 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK69795.1 - 4.2e-10 39.8 0.7 5.8e-10 39.4 0.7 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 ABK69795.1 - 0.0036 17.2 0.4 0.0062 16.4 0.4 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 ABK69795.1 - 0.011 16.0 0.2 1.6 9.0 0.1 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 ABK69795.1 - 0.071 12.5 0.0 6.8 6.0 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Glyco_tranf_2_3 PF13641.6 ABK69795.1 - 0.087 12.7 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 NadA PF02445.16 ABK69796.1 - 5.1e-109 364.0 0.1 5.8e-109 363.8 0.1 1.0 1 0 0 1 1 1 1 Quinolinate synthetase A protein GMC_oxred_N PF00732.19 ABK69797.1 - 5.5e-70 236.1 0.0 7.5e-70 235.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ABK69797.1 - 2.1e-36 125.6 0.3 4.1e-36 124.7 0.3 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ABK69797.1 - 7.9e-10 38.4 0.3 3.7e-06 26.3 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 ABK69797.1 - 1.5e-05 24.3 0.0 2.4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 ABK69797.1 - 9e-05 22.2 0.9 0.011 15.3 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ABK69797.1 - 0.00046 20.4 0.8 0.0023 18.1 0.1 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ABK69797.1 - 0.0012 18.1 0.0 0.0021 17.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 ABK69797.1 - 0.0034 16.7 0.0 0.0076 15.5 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ABK69797.1 - 0.0076 15.0 0.1 0.035 12.8 0.0 2.0 3 0 0 3 3 3 1 HI0933-like protein ApbA PF02558.16 ABK69797.1 - 0.034 13.8 0.0 0.072 12.7 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 ABK69797.1 - 0.071 12.4 0.5 3.4 6.8 0.0 2.6 3 0 0 3 3 3 0 FAD binding domain PhoLip_ATPase_C PF16212.5 ABK69798.1 - 0.0081 15.9 12.1 0.0081 15.9 12.1 1.6 1 1 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal EamA PF00892.20 ABK69798.1 - 0.11 12.7 42.6 0.14 12.4 12.1 4.2 1 1 1 4 4 4 0 EamA-like transporter family 7TM_GPCR_Str PF10326.9 ABK69798.1 - 0.12 11.7 3.4 3.4 6.9 0.2 2.3 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Str DUF962 PF06127.11 ABK69798.1 - 0.23 11.6 9.2 3.5 7.8 3.0 3.2 1 1 0 2 2 2 0 Protein of unknown function (DUF962) DUF2070 PF09843.9 ABK69798.1 - 4.1 5.6 26.0 0.29 9.4 20.3 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) Zn_peptidase PF04228.13 ABK69799.1 - 2.7e-09 36.9 1.3 5.8e-07 29.2 0.2 3.3 2 2 0 2 2 2 1 Putative neutral zinc metallopeptidase Zn_peptidase_2 PF04298.12 ABK69799.1 - 0.021 14.2 0.1 0.021 14.2 0.1 1.5 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase Peptidase_M4 PF01447.18 ABK69799.1 - 0.14 12.6 0.1 0.22 12.0 0.1 1.3 1 0 0 1 1 1 0 Thermolysin metallopeptidase, catalytic domain MPTase-PolyVal PF18818.1 ABK69799.1 - 0.21 11.6 0.0 0.42 10.7 0.0 1.4 1 0 0 1 1 1 0 Metallopeptidase superfamily domain AMP-binding PF00501.28 ABK69800.1 - 5.5e-177 588.6 1.1 3.7e-91 305.8 0.2 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 ABK69800.1 - 1.4e-99 333.8 0.0 2.6e-73 247.2 0.0 2.1 2 0 0 2 2 2 2 Condensation domain NAD_binding_4 PF07993.12 ABK69800.1 - 3.8e-53 180.3 0.0 5.4e-53 179.8 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 ABK69800.1 - 2.7e-23 82.1 0.9 6.2e-11 42.5 0.1 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 ABK69800.1 - 5.9e-20 72.0 0.5 7.8e-09 36.4 0.1 3.2 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Epimerase PF01370.21 ABK69800.1 - 2.5e-05 23.9 0.0 4.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ABK69800.1 - 0.049 12.6 0.0 0.38 9.7 0.0 2.1 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ribosomal_S16 PF00886.19 ABK69801.1 - 1.6e-22 79.3 0.2 2.4e-22 78.7 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 DoxX_3 PF13781.6 ABK69802.1 - 0.00075 20.1 1.5 0.00098 19.7 0.7 1.6 2 0 0 2 2 2 1 DoxX-like family DoxX_2 PF13564.6 ABK69802.1 - 0.0032 17.5 1.3 0.0043 17.1 1.3 1.3 1 0 0 1 1 1 1 DoxX-like family DoxX PF07681.12 ABK69802.1 - 0.023 15.3 3.2 0.048 14.3 3.2 1.6 1 1 0 1 1 1 0 DoxX Fe-S_biosyn PF01521.20 ABK69803.1 - 5.6e-20 71.6 0.0 6.3e-20 71.4 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis ECH_1 PF00378.20 ABK69804.1 - 1.2e-45 155.8 0.0 1.4e-45 155.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK69804.1 - 2.4e-28 99.6 0.0 4.3e-28 98.8 0.0 1.4 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase DIOX_N PF14226.6 ABK69805.1 - 1e-34 119.8 0.0 2.3e-34 118.7 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ABK69805.1 - 1.3e-18 67.4 0.0 5.4e-18 65.3 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily TetR_N PF00440.23 ABK69806.1 - 0.00013 21.7 0.0 0.00024 20.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family LysR_substrate PF03466.20 ABK69807.1 - 1.1e-49 168.6 8.0 1.6e-49 168.1 8.0 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 ABK69807.1 - 2.6e-20 72.1 0.2 1.4e-19 69.7 0.1 2.4 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 ABK69807.1 - 4.4e-05 23.3 0.4 0.0021 17.9 0.0 3.3 3 2 0 3 3 3 1 MarR family HTH_8 PF02954.19 ABK69807.1 - 0.00037 20.2 0.0 0.00069 19.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family HTH_30 PF13556.6 ABK69807.1 - 0.0014 18.3 0.1 0.0029 17.4 0.1 1.4 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.6 ABK69807.1 - 0.0023 18.0 0.0 0.011 15.8 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_5 PF01022.20 ABK69807.1 - 0.0027 17.6 0.0 0.0072 16.2 0.0 1.7 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family GntR PF00392.21 ABK69807.1 - 0.003 17.2 0.1 0.15 11.7 0.0 2.6 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 ABK69807.1 - 0.0044 16.6 0.0 0.02 14.4 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 ABK69807.1 - 0.0047 16.7 0.0 0.021 14.6 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain SBP_bac_11 PF13531.6 ABK69807.1 - 0.012 15.4 0.8 2.3 7.9 0.0 2.5 2 1 0 2 2 2 0 Bacterial extracellular solute-binding protein HTH_Crp_2 PF13545.6 ABK69807.1 - 0.031 14.2 0.3 0.12 12.4 0.0 2.1 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_20 PF12840.7 ABK69807.1 - 0.047 13.8 0.2 0.28 11.3 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain MarR PF01047.22 ABK69807.1 - 0.1 12.5 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 MarR family Glucosamine_iso PF01182.20 ABK69808.1 - 2e-20 73.7 0.0 3e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Sugar-bind PF04198.13 ABK69808.1 - 0.0098 15.0 0.1 0.087 11.9 0.1 2.1 1 1 0 1 1 1 1 Putative sugar-binding domain Abhydrolase_1 PF00561.20 ABK69809.1 - 1.7e-27 96.7 0.1 2.2e-27 96.3 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK69809.1 - 1.2e-17 65.3 9.6 1.5e-17 65.0 9.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK69809.1 - 1.6e-13 50.5 0.6 8.2e-13 48.2 0.6 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF2267 PF10025.9 ABK69809.1 - 0.023 15.0 0.7 0.048 13.9 0.2 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) TPP_enzyme_N PF02776.18 ABK69809.1 - 0.042 13.5 0.4 0.27 10.8 0.0 2.3 3 1 0 3 3 3 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Abhydrolase_4 PF08386.10 ABK69809.1 - 0.047 13.8 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein Peptidase_S15 PF02129.18 ABK69809.1 - 0.11 12.1 0.0 0.33 10.5 0.0 1.8 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Nsp3_PL2pro PF12124.8 ABK69809.1 - 0.2 11.5 0.0 0.45 10.3 0.0 1.5 1 0 0 1 1 1 0 Coronavirus polyprotein cleavage domain Whib PF02467.16 ABK69810.1 - 1.5e-21 76.8 3.0 2.6e-21 76.0 3.0 1.4 1 0 0 1 1 1 1 Transcription factor WhiB Lipid_DES PF08557.10 ABK69810.1 - 0.11 12.0 0.1 0.37 10.3 0.0 1.8 2 0 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) HEPN_SAV_6107 PF18726.1 ABK69810.1 - 0.5 10.9 7.0 0.3 11.6 1.1 2.3 1 1 1 2 2 2 0 SAV_6107-like HEPN Cu-oxidase_4 PF02578.15 ABK69811.1 - 2.1e-72 243.5 1.0 2.4e-72 243.3 1.0 1.0 1 0 0 1 1 1 1 Multi-copper polyphenol oxidoreductase laccase XhoI PF04555.13 ABK69812.1 - 0.2 11.5 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease XhoI Peptidase_S49 PF01343.18 ABK69813.1 - 4.9e-90 299.4 0.0 1.2e-46 158.5 0.1 2.1 2 0 0 2 2 2 2 Peptidase family S49 CLP_protease PF00574.23 ABK69813.1 - 1.5e-06 28.2 0.5 0.039 13.8 0.3 3.2 3 0 0 3 3 3 3 Clp protease PRODH PF18327.1 ABK69813.1 - 0.008 16.4 2.0 0.008 16.4 2.0 3.3 5 0 0 5 5 5 1 Proline utilization A proline dehydrogenase N-terminal domain ECH_1 PF00378.20 ABK69813.1 - 0.022 14.1 0.1 0.53 9.6 0.1 2.7 3 0 0 3 3 3 0 Enoyl-CoA hydratase/isomerase SDH_sah PF01972.16 ABK69813.1 - 0.06 12.3 0.1 0.1 11.6 0.1 1.3 1 0 0 1 1 1 0 Serine dehydrogenase proteinase Tubulin PF00091.25 ABK69814.1 - 1.2e-39 136.5 0.1 1.9e-39 135.9 0.1 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 ABK69814.1 - 1.3e-35 121.6 1.7 3.3e-35 120.2 1.7 1.7 1 0 0 1 1 1 1 FtsZ family, C-terminal domain FMN_red PF03358.15 ABK69815.1 - 1.7e-33 115.5 0.2 2.7e-33 114.9 0.2 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 ABK69815.1 - 1.8e-07 31.0 0.0 2.8e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold NAD_binding_10 PF13460.6 ABK69816.1 - 7.4e-21 74.9 0.4 1.3e-20 74.1 0.4 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ABK69816.1 - 8e-14 51.8 0.0 1e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 ABK69816.1 - 2.9e-12 46.6 0.0 4.2e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ABK69816.1 - 2.5e-07 30.0 0.0 3.6e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ABK69816.1 - 0.0006 19.3 0.0 0.00083 18.9 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF2867 PF11066.8 ABK69816.1 - 0.0041 17.5 0.0 0.0088 16.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2867) PAC2 PF09754.9 ABK69816.1 - 0.005 16.9 0.0 0.0089 16.1 0.0 1.4 1 0 0 1 1 1 1 PAC2 family RmlD_sub_bind PF04321.17 ABK69816.1 - 0.011 14.9 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.25 ABK69816.1 - 0.18 11.2 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase FecCD PF01032.18 ABK69817.1 - 0.0028 16.7 2.0 0.0035 16.4 2.0 1.1 1 0 0 1 1 1 1 FecCD transport family Phage_holin_2_1 PF04971.12 ABK69817.1 - 0.012 15.6 1.4 0.026 14.5 1.4 1.6 1 1 0 1 1 1 0 Bacteriophage P21 holin S Romo1 PF10247.9 ABK69817.1 - 0.47 10.9 5.4 3.5 8.1 0.7 2.2 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 ECF_trnsprt PF12822.7 ABK69817.1 - 7 6.7 10.1 0.42 10.7 0.8 2.1 1 1 1 2 2 2 0 ECF transporter, substrate-specific component ThrE PF06738.12 ABK69818.1 - 6.9e-44 150.0 24.0 2.4e-43 148.2 5.9 2.1 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 ABK69818.1 - 1.3e-06 28.6 27.6 0.00078 19.6 9.5 2.2 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE HisKA_3 PF07730.13 ABK69819.1 - 3.1e-09 37.2 0.9 1.1e-08 35.4 0.9 2.1 1 0 0 1 1 1 1 Histidine kinase GAF_2 PF13185.6 ABK69819.1 - 1.5e-08 35.1 0.0 3e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 GAF domain HATPase_c PF02518.26 ABK69819.1 - 0.00034 21.1 0.1 0.014 15.9 0.1 2.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.26 ABK69819.1 - 0.0009 19.9 0.1 0.0043 17.7 0.0 2.0 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 ABK69819.1 - 0.0024 18.2 0.0 0.0049 17.2 0.0 1.5 1 0 0 1 1 1 1 GAF domain HATPase_c_2 PF13581.6 ABK69819.1 - 0.004 17.1 0.1 0.0088 16.0 0.1 1.7 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain TetR_N PF00440.23 ABK69820.1 - 1.5e-15 56.7 0.0 1.5e-15 56.7 0.0 1.6 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_31 PF13560.6 ABK69820.1 - 0.085 13.2 0.6 0.29 11.5 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain IclR PF01614.18 ABK69821.1 - 3.6e-20 72.1 0.5 2.4e-19 69.4 0.5 2.0 1 1 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 ABK69821.1 - 1.5e-11 43.9 2.5 2.5e-11 43.2 1.2 2.1 2 0 0 2 2 2 1 IclR helix-turn-helix domain MarR_2 PF12802.7 ABK69821.1 - 0.00032 20.5 0.3 0.00032 20.5 0.3 2.1 2 0 0 2 2 2 1 MarR family Trns_repr_metal PF02583.17 ABK69823.1 - 6.4e-31 106.6 2.3 7.5e-31 106.3 2.3 1.0 1 0 0 1 1 1 1 Metal-sensitive transcriptional repressor YojJ PF10372.9 ABK69823.1 - 0.025 14.7 0.0 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus IclR PF01614.18 ABK69824.1 - 3.2e-24 85.2 0.1 4.8e-24 84.6 0.1 1.3 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 ABK69824.1 - 2.5e-13 49.6 1.3 1.6e-12 47.1 0.5 2.6 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_20 PF12840.7 ABK69824.1 - 0.00026 21.0 0.4 0.023 14.8 0.2 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 ABK69824.1 - 0.00045 19.7 2.4 0.0029 17.1 0.0 3.2 5 0 0 5 5 5 1 Sigma-70, region 4 MarR_2 PF12802.7 ABK69824.1 - 0.0046 16.8 0.1 0.013 15.4 0.1 1.8 1 0 0 1 1 1 1 MarR family DUF742 PF05331.11 ABK69824.1 - 0.012 15.4 0.0 0.043 13.6 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF742) Rrf2 PF02082.20 ABK69824.1 - 0.017 15.4 0.0 0.045 14.1 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator HTH_24 PF13412.6 ABK69824.1 - 0.03 13.9 0.0 0.069 12.7 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 ABK69824.1 - 0.034 13.9 0.1 0.17 11.7 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain HTH_DeoR PF08220.12 ABK69824.1 - 0.066 13.0 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Aldedh PF00171.22 ABK69825.1 - 1e-138 462.7 2.6 1.2e-138 462.5 2.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Methyltransf_24 PF13578.6 ABK69827.1 - 5.5e-20 72.4 0.0 9.1e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.12 ABK69827.1 - 7.3e-06 25.8 0.0 2e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Cephalosporin hydroxylase TylF PF05711.11 ABK69827.1 - 0.0021 17.4 0.0 0.0029 16.9 0.0 1.2 1 0 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) NAD_binding_1 PF00175.21 ABK69828.1 - 1.7e-14 54.4 0.0 2.4e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 ABK69828.1 - 1.3e-09 38.3 0.0 2.1e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 ABK69828.1 - 1e-05 25.7 0.0 0.00097 19.3 0.0 2.1 1 1 1 2 2 2 2 Ferric reductase NAD binding domain SBP_bac_8 PF13416.6 ABK69829.1 - 3.6e-33 115.6 7.6 4.9e-33 115.2 7.6 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 ABK69829.1 - 8.1e-32 111.4 10.3 1.3e-31 110.7 10.3 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein PE PF00934.20 ABK69830.1 - 4.3e-14 52.6 19.1 5e-14 52.4 19.1 1.0 1 0 0 1 1 1 1 PE family Ferritin PF00210.24 ABK69831.1 - 1.2e-21 77.2 0.0 1.4e-21 76.9 0.0 1.0 1 0 0 1 1 1 1 Ferritin-like domain WES_acyltransf PF03007.16 ABK69832.1 - 1.1e-59 202.4 3.3 1.1e-59 202.4 3.3 2.1 2 0 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 ABK69832.1 - 5.6e-24 84.7 0.0 8.7e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) Subtilosin_A PF11420.8 ABK69832.1 - 0.025 14.5 0.0 0.08 12.9 0.0 1.8 1 0 0 1 1 1 0 Bacteriocin subtilosin A Condensation PF00668.20 ABK69832.1 - 0.034 12.8 0.1 0.26 9.9 0.1 1.9 2 0 0 2 2 2 0 Condensation domain DUF5632 PF18646.1 ABK69833.1 - 0.052 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5632) DDE_Tnp_ISL3 PF01610.17 ABK69834.1 - 1.6e-64 217.9 0.0 2.1e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Transposase zf-ISL3 PF14690.6 ABK69834.1 - 1.1e-09 38.8 4.6 1.8e-09 38.1 2.5 2.5 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HTH_Tnp_ISL3 PF13542.6 ABK69834.1 - 2.4e-08 33.2 1.6 7e-08 31.8 1.6 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 adh_short PF00106.25 ABK69835.1 - 9e-40 136.2 2.1 1.6e-39 135.4 2.1 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK69835.1 - 5.4e-33 114.5 3.7 1e-32 113.6 3.7 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK69835.1 - 5.8e-14 52.4 1.0 8.8e-14 51.8 1.0 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 ABK69836.1 - 5.4e-44 150.0 0.5 7.1e-44 149.6 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK69836.1 - 8.4e-44 149.9 1.7 2.4e-43 148.4 1.7 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK69836.1 - 4.5e-09 36.5 0.2 7.3e-09 35.8 0.2 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 ABK69836.1 - 0.011 15.1 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 ABK69836.1 - 0.031 13.7 0.0 0.13 11.7 0.1 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 ABK69836.1 - 0.061 12.6 0.1 0.12 11.7 0.1 1.6 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 4HBT_3 PF13622.6 ABK69837.1 - 4.1e-40 138.6 5.5 5e-40 138.3 5.5 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 ABK69837.1 - 9.9e-19 67.5 0.0 2.1e-15 56.7 0.0 2.7 2 1 0 2 2 2 2 Acyl-CoA thioesterase ketoacyl-synt PF00109.26 ABK69838.1 - 5e-48 163.9 3.1 2.6e-47 161.5 0.7 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 ABK69838.1 - 2e-32 111.7 0.6 3.8e-32 110.8 0.6 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 ABK69838.1 - 2.5e-07 30.3 1.8 5e-07 29.4 0.7 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ABK69838.1 - 0.83 9.3 5.9 0.064 12.9 0.4 1.9 2 0 0 2 2 2 0 Thiolase, C-terminal domain EutN_CcmL PF03319.13 ABK69839.1 - 9.5e-18 64.6 0.0 1.1e-17 64.4 0.0 1.0 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutN/carboxysome SDH_C PF18317.1 ABK69839.1 - 0.063 13.1 0.0 0.098 12.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate 5'-dehydrogenase C-terminal domain adh_short_C2 PF13561.6 ABK69840.1 - 3.5e-62 210.0 10.1 4.1e-62 209.8 10.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK69840.1 - 7.3e-61 205.0 6.1 8.6e-61 204.8 6.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK69840.1 - 1.4e-13 51.2 4.0 2e-13 50.6 4.0 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 ABK69840.1 - 0.00049 19.4 0.2 0.0013 18.1 0.1 1.7 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_2 PF03446.15 ABK69840.1 - 0.008 16.4 0.5 0.018 15.3 0.5 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Epimerase PF01370.21 ABK69840.1 - 0.02 14.4 1.0 0.03 13.8 1.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 ABK69840.1 - 0.056 13.5 0.5 0.13 12.3 0.4 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase YjeF_N PF03853.15 ABK69840.1 - 0.1 12.5 2.4 0.44 10.4 0.2 2.2 2 0 0 2 2 2 0 YjeF-related protein N-terminus DDE_Tnp_ISL3 PF01610.17 ABK69841.1 - 1.6e-64 217.9 0.0 2.1e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Transposase zf-ISL3 PF14690.6 ABK69841.1 - 1.1e-09 38.8 4.6 1.8e-09 38.1 2.5 2.5 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HTH_Tnp_ISL3 PF13542.6 ABK69841.1 - 2.4e-08 33.2 1.6 7e-08 31.8 1.6 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 Hydrolase_4 PF12146.8 ABK69842.1 - 9.4e-16 57.8 1.3 2.6e-15 56.3 1.3 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ABK69842.1 - 7.4e-12 46.3 10.4 1e-11 45.8 10.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ABK69842.1 - 1.9e-10 40.8 0.0 4.3e-09 36.4 0.1 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 ABK69842.1 - 3.2e-08 33.4 0.1 0.001 18.7 0.0 2.5 2 1 0 2 2 2 2 Dienelactone hydrolase family AXE1 PF05448.12 ABK69842.1 - 8.4e-06 24.7 0.5 0.003 16.3 0.1 2.2 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 ABK69842.1 - 4.1e-05 23.3 0.9 7e-05 22.6 0.7 1.4 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 ABK69842.1 - 0.00064 19.2 0.3 0.055 12.9 0.2 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.11 ABK69842.1 - 0.007 16.3 0.0 0.047 13.6 0.0 1.9 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S28 PF05577.12 ABK69842.1 - 0.049 12.4 0.1 0.063 12.1 0.1 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 DUF2368 PF10166.9 ABK69842.1 - 0.18 11.4 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) PMT_2 PF13231.6 ABK69843.1 - 1.1e-27 97.2 12.4 1.1e-27 97.2 12.4 3.4 2 1 2 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT PF02366.18 ABK69843.1 - 2.9e-06 27.0 7.1 2.9e-06 27.0 7.1 2.2 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase GT87 PF09594.10 ABK69843.1 - 0.0002 21.2 38.9 0.0002 21.2 38.9 4.4 1 1 1 3 3 3 1 Glycosyltransferase family 87 Mfp-3 PF04202.13 ABK69843.1 - 0.088 13.2 0.8 0.45 11.0 0.4 2.5 2 0 0 2 2 2 0 Foot protein 3 7TM-7TMR_HD PF07698.11 ABK69843.1 - 0.095 12.5 22.5 0.4 10.4 5.5 3.7 2 2 1 3 3 3 0 7TM receptor with intracellular HD hydrolase Bax1-I PF01027.20 ABK69843.1 - 6.9 6.4 23.6 0.056 13.3 7.7 2.6 2 1 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 PE PF00934.20 ABK69844.1 - 0.0051 17.1 5.6 0.033 14.5 0.0 2.8 2 0 0 2 2 2 1 PE family Baculo_PEP_C PF04513.12 ABK69844.1 - 0.0071 16.4 11.1 0.13 12.3 4.0 2.3 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Rib_hydrolayse PF02267.17 ABK69844.1 - 0.0071 15.8 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosyl cyclase DUF1664 PF07889.12 ABK69844.1 - 0.026 14.6 1.3 0.36 10.9 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ApoLp-III PF07464.11 ABK69844.1 - 0.03 14.4 2.1 3.5 7.7 0.6 2.3 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) MCPsignal PF00015.21 ABK69844.1 - 0.057 13.2 4.0 0.41 10.4 2.2 2.2 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Exo70 PF03081.15 ABK69844.1 - 0.066 12.3 0.1 0.14 11.2 0.1 1.4 1 1 0 1 1 1 0 Exo70 exocyst complex subunit RmuC PF02646.16 ABK69844.1 - 0.078 12.1 1.4 4 6.5 0.1 2.2 1 1 1 2 2 2 0 RmuC family Prominin PF05478.11 ABK69844.1 - 0.086 10.8 0.6 0.23 9.4 0.3 1.6 1 1 1 2 2 2 0 Prominin WXG100 PF06013.12 ABK69844.1 - 0.11 12.7 0.8 2.7 8.3 0.0 3.0 1 1 1 2 2 2 0 Proteins of 100 residues with WXG T7SS_ESX_EspC PF10824.8 ABK69844.1 - 0.21 12.1 8.5 1.4 9.4 6.5 3.3 3 1 1 4 4 3 0 Excreted virulence factor EspC, type VII ESX diderm DUF948 PF06103.11 ABK69844.1 - 0.35 11.2 5.0 0.89 9.9 1.1 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Bacillus_HBL PF05791.11 ABK69844.1 - 0.83 9.4 4.4 1 9.2 0.3 2.1 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) EamA PF00892.20 ABK69845.1 - 3.5e-32 111.4 36.2 1e-18 67.8 12.0 2.0 2 0 0 2 2 2 2 EamA-like transporter family Cob_adeno_trans PF01923.18 ABK69847.1 - 3.4e-58 196.4 0.0 3.8e-58 196.3 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase Molybdopterin PF00384.22 ABK69848.1 - 7.6e-20 71.3 0.0 1.3e-13 50.8 0.0 2.1 2 0 0 2 2 2 2 Molybdopterin oxidoreductase Fer2_4 PF13510.6 ABK69848.1 - 5.4e-18 64.8 0.2 1.6e-17 63.3 0.2 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 ABK69848.1 - 5.1e-16 57.9 0.2 1.3e-15 56.6 0.2 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Molydop_binding PF01568.21 ABK69848.1 - 2.2e-10 40.6 0.1 6.8e-10 39.0 0.1 1.8 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Fer2 PF00111.27 ABK69848.1 - 5.8e-07 29.4 0.1 5.8e-07 29.4 0.1 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Molybdop_Fe4S4 PF04879.16 ABK69848.1 - 0.0013 18.6 0.3 0.0035 17.3 0.3 1.7 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain Fer4 PF00037.27 ABK69848.1 - 0.49 10.3 4.9 3.9 7.4 0.2 2.9 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_7 PF12838.7 ABK69848.1 - 0.82 10.3 6.1 6.9 7.3 0.3 2.7 2 0 0 2 2 2 0 4Fe-4S dicluster domain Dak2 PF02734.17 ABK69849.1 - 3.6e-54 183.3 10.7 4.3e-54 183.0 10.7 1.1 1 0 0 1 1 1 1 DAK2 domain DUF4383 PF14325.6 ABK69850.1 - 1.8e-47 160.7 16.3 2.1e-47 160.5 16.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4383) DUF2162 PF09930.9 ABK69850.1 - 0.0018 17.8 2.1 0.0018 17.8 2.1 1.9 1 1 1 2 2 2 1 Predicted transporter (DUF2162) LysE PF01810.18 ABK69850.1 - 0.0032 16.9 6.0 0.034 13.6 3.4 2.2 2 0 0 2 2 2 1 LysE type translocator Tetraspanin PF00335.20 ABK69850.1 - 0.0084 15.8 0.7 0.0084 15.8 0.7 2.2 1 1 1 2 2 2 1 Tetraspanin family DUF3185 PF11381.8 ABK69850.1 - 0.095 12.7 0.1 0.095 12.7 0.1 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3185) YtpI PF14007.6 ABK69850.1 - 0.11 12.6 0.1 0.11 12.6 0.1 2.8 3 1 0 3 3 3 0 YtpI-like protein E1-E2_ATPase PF00122.20 ABK69850.1 - 0.81 9.2 2.7 2 7.9 0.2 2.1 1 1 1 2 2 2 0 E1-E2 ATPase CD20 PF04103.15 ABK69850.1 - 4.5 7.3 11.0 20 5.3 0.2 2.4 2 1 0 2 2 2 0 CD20-like family CoA_trans PF01144.23 ABK69851.1 - 8.4e-44 149.5 0.2 9.5e-44 149.4 0.2 1.0 1 0 0 1 1 1 1 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 ABK69851.1 - 0.00012 22.1 0.6 0.00017 21.5 0.6 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain IF-2B PF01008.17 ABK69851.1 - 0.054 12.7 0.5 0.37 9.9 0.4 2.0 2 0 0 2 2 2 0 Initiation factor 2 subunit family TetR_N PF00440.23 ABK69852.1 - 1.7e-12 46.9 0.4 3.7e-12 45.8 0.1 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 ABK69852.1 - 5.5e-05 23.5 3.2 5.5e-05 23.5 3.2 2.1 2 2 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain HTH_7 PF02796.15 ABK69852.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase PBP_like_2 PF12849.7 ABK69853.1 - 0.028 14.1 0.0 0.034 13.8 0.0 1.1 1 0 0 1 1 1 0 PBP superfamily domain HTH_3 PF01381.22 ABK69854.1 - 4.7e-08 33.0 0.6 0.0046 17.0 0.1 2.7 2 1 0 2 2 2 2 Helix-turn-helix HTH_31 PF13560.6 ABK69854.1 - 4.3e-07 30.2 12.3 1.8e-06 28.2 1.0 3.1 2 1 0 2 2 2 2 Helix-turn-helix domain HTH_19 PF12844.7 ABK69854.1 - 5.9e-06 26.2 0.4 0.011 15.7 0.0 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain Calpain_inhib PF00748.19 ABK69854.1 - 0.7 10.4 4.4 1 9.8 0.2 2.2 2 0 0 2 2 2 0 Calpain inhibitor HTH_25 PF13413.6 ABK69854.1 - 0.74 9.7 5.0 0.7 9.8 0.2 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain CAP_N PF01213.19 ABK69854.1 - 8 5.8 8.4 1.1 8.7 3.8 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Methyltransf_11 PF08241.12 ABK69855.1 - 2.1e-17 63.6 0.2 8.8e-17 61.6 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABK69855.1 - 1.1e-15 57.8 0.0 1.5e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABK69855.1 - 5.8e-13 49.4 0.1 2.5e-12 47.3 0.1 2.1 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK69855.1 - 6.4e-13 49.3 0.0 1.2e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABK69855.1 - 1.2e-09 38.2 0.0 1.7e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 ABK69855.1 - 5.1e-05 22.5 0.0 7.1e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MetW PF07021.12 ABK69855.1 - 0.0043 16.7 0.0 0.0066 16.1 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_PK PF05891.12 ABK69855.1 - 0.0096 15.5 0.0 0.015 14.8 0.0 1.4 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase DREV PF05219.12 ABK69855.1 - 0.011 14.8 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_24 PF13578.6 ABK69855.1 - 0.021 15.9 0.3 0.15 13.1 0.2 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_2 PF00891.18 ABK69855.1 - 0.021 14.1 0.1 0.049 12.9 0.0 1.4 1 1 0 1 1 1 0 O-methyltransferase domain Bin3 PF06859.12 ABK69855.1 - 0.031 14.9 0.0 0.064 13.9 0.0 1.5 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) TrkA_N PF02254.18 ABK69855.1 - 0.031 14.5 0.1 0.064 13.5 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain MTS PF05175.14 ABK69855.1 - 0.036 13.6 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain NodS PF05401.11 ABK69855.1 - 0.038 13.6 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) NmrA PF05368.13 ABK69855.1 - 0.041 13.4 0.1 0.1 12.1 0.1 1.7 1 1 0 1 1 1 0 NmrA-like family CMAS PF02353.20 ABK69855.1 - 0.048 12.9 0.1 0.083 12.2 0.1 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase UDPG_MGDP_dh_N PF03721.14 ABK69855.1 - 0.064 12.8 0.0 0.097 12.2 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain CheR PF01739.18 ABK69855.1 - 0.17 11.4 0.0 0.4 10.1 0.0 1.5 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain DRE2_N PF16803.5 ABK69855.1 - 0.22 11.8 0.0 0.64 10.3 0.0 1.9 1 1 0 1 1 1 0 Fe-S cluster assembly protein DRE2 N-terminus adh_short PF00106.25 ABK69856.1 - 2e-31 109.0 0.0 2.9e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK69856.1 - 5.1e-22 78.6 0.1 7.4e-22 78.0 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK69856.1 - 1.6e-10 41.2 0.1 5.1e-10 39.6 0.1 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK69856.1 - 4.6e-06 26.3 0.0 8.4e-06 25.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ABK69856.1 - 2.9e-05 24.1 0.4 5.8e-05 23.1 0.4 1.5 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 ABK69856.1 - 0.085 11.9 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain FMN_red PF03358.15 ABK69857.1 - 1.2e-11 44.6 0.8 3.8e-10 39.7 0.7 2.3 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_5 PF12724.7 ABK69857.1 - 1.8e-08 34.7 0.0 2.8e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_1 PF00258.25 ABK69857.1 - 5.3e-06 26.7 0.0 5.8e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.17 ABK69857.1 - 0.0023 17.7 0.1 0.01 15.5 0.1 2.1 1 1 0 1 1 1 1 Flavodoxin-like fold PTS_IIB PF02302.17 ABK69857.1 - 0.094 13.4 0.1 0.18 12.5 0.1 1.4 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIB subunit Flavodoxin_3 PF12641.7 ABK69857.1 - 0.18 11.5 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain BPD_transp_1 PF00528.22 ABK69858.1 - 1.3e-25 90.2 47.8 6e-15 55.4 9.7 3.9 3 1 1 4 4 4 3 Binding-protein-dependent transport system inner membrane component MttA_Hcf106 PF02416.16 ABK69858.1 - 0.075 12.4 0.4 3 7.2 0.0 3.2 2 0 0 2 2 2 0 mttA/Hcf106 family Dynamin_N PF00350.23 ABK69859.1 - 4.2e-13 49.7 0.0 1.2e-12 48.2 0.0 1.8 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 ABK69859.1 - 5.8e-06 26.4 0.0 5.6e-05 23.2 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase Fer4_15 PF13459.6 ABK69859.1 - 0.062 14.0 0.0 0.37 11.6 0.0 2.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain BST2 PF16716.5 ABK69859.1 - 1.2 9.7 8.2 1.4 9.6 3.7 2.5 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 MnmE_helical PF12631.7 ABK69859.1 - 1.6 8.9 7.1 14 5.7 7.1 2.4 1 1 0 1 1 1 0 MnmE helical domain V-SNARE PF05008.15 ABK69859.1 - 3.7 8.0 9.6 15 6.0 0.5 3.4 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus FAS_I_H PF18314.1 ABK69859.1 - 4.7 6.8 8.2 0.48 10.0 2.0 2.4 2 1 1 3 3 3 0 Fatty acid synthase type I helical domain GCN5L1 PF06320.13 ABK69859.1 - 5.2 7.2 10.5 8.3 6.6 4.1 2.6 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) AP_endonuc_2 PF01261.24 ABK69860.1 - 6.1e-08 32.4 0.2 2.3e-07 30.5 0.2 1.8 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel NAD_synthase PF02540.17 ABK69861.1 - 1.1e-21 77.0 0.0 1.6e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.22 ABK69861.1 - 4.3e-17 62.3 0.0 7.3e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TetR_N PF00440.23 ABK69862.1 - 9.2e-19 67.0 0.0 1.8e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_7 PF02796.15 ABK69862.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase DUF732 PF05305.14 ABK69863.1 - 7.8e-25 87.1 0.3 1.1e-24 86.6 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF732) Pyr_redox_2 PF07992.14 ABK69864.1 - 2.3e-12 46.7 0.1 1.7e-09 37.4 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4 PF00037.27 ABK69864.1 - 3.4e-11 42.5 19.8 9e-09 34.8 6.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 ABK69864.1 - 2.5e-07 31.2 13.1 4.7e-07 30.3 13.1 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 ABK69864.1 - 3.4e-07 30.1 5.4 3.4e-07 30.1 5.4 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_2 PF12797.7 ABK69864.1 - 3.2e-06 26.9 15.0 4.6e-06 26.4 3.6 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_9 PF13187.6 ABK69864.1 - 5.9e-06 26.3 10.6 1.1e-05 25.5 10.6 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 ABK69864.1 - 8e-06 26.7 8.3 0.0001 23.2 0.4 2.4 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain FAD_binding_3 PF01494.19 ABK69864.1 - 2e-05 24.0 0.0 3.9e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 ABK69864.1 - 4.3e-05 24.0 0.0 0.51 10.9 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ABK69864.1 - 0.00015 21.9 0.0 0.00036 20.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Fer4_10 PF13237.6 ABK69864.1 - 0.00018 21.6 2.7 0.00018 21.6 2.7 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 ABK69864.1 - 0.00061 20.1 4.0 0.00061 20.1 4.0 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.6 ABK69864.1 - 0.003 17.7 14.7 0.0091 16.1 14.7 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 ABK69864.1 - 0.0074 16.7 0.2 0.0074 16.7 0.2 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain HI0933_like PF03486.14 ABK69864.1 - 0.011 14.4 0.0 0.018 13.7 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_7 PF13241.6 ABK69864.1 - 0.013 15.9 0.1 1 9.8 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Thi4 PF01946.17 ABK69864.1 - 0.017 14.4 0.0 1.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 ABK69864.1 - 0.019 14.9 0.0 0.048 13.6 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Fer4_17 PF13534.6 ABK69864.1 - 0.041 14.4 9.9 0.098 13.2 0.1 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Shikimate_DH PF01488.20 ABK69864.1 - 0.2 11.7 0.1 9.1 6.3 0.1 2.9 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Fer4_3 PF12798.7 ABK69864.1 - 0.92 10.6 24.1 0.12 13.4 8.0 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain HD PF01966.22 ABK69865.1 - 1.3e-08 35.1 0.0 2e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 HD domain Abhydrolase_3 PF07859.13 ABK69867.1 - 3.2e-70 236.3 1.4 5e-70 235.6 1.4 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ABK69867.1 - 1.8e-06 27.2 0.5 9.8e-06 24.7 0.3 2.1 1 1 1 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.21 ABK69867.1 - 0.084 12.3 0.1 0.28 10.6 0.1 1.7 1 1 0 1 1 1 0 Prolyl oligopeptidase family ALAD PF00490.21 ABK69868.1 - 1.5e-132 441.6 0.0 1.6e-132 441.5 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Peptidase_M13_N PF05649.13 ABK69870.1 - 1e-101 341.4 0.0 1.3e-101 341.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 ABK69870.1 - 1e-78 263.7 0.0 1.6e-78 263.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M48 PF01435.18 ABK69870.1 - 0.011 15.5 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M48 NTP_transf_9 PF04248.12 ABK69871.1 - 2.2e-31 107.6 0.1 2.3e-28 97.9 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF427) adh_short_C2 PF13561.6 ABK69873.1 - 4.4e-47 160.6 4.0 2e-46 158.4 4.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK69873.1 - 3.5e-41 140.8 3.1 3.3e-40 137.6 3.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK69873.1 - 0.002 18.1 1.0 0.0033 17.4 1.0 1.3 1 0 0 1 1 1 1 KR domain Sulfate_transp PF00916.20 ABK69874.1 - 9.6e-71 238.5 33.8 1.2e-70 238.2 33.8 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ABK69874.1 - 4.5e-16 58.5 0.0 8.1e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 ABK69874.1 - 0.0031 17.8 5.6 0.0039 17.5 0.0 3.4 3 0 0 3 3 3 1 STAS domain Acyltransferase PF01553.21 ABK69875.1 - 4.4e-17 62.0 0.0 7.3e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DAGAT PF03982.13 ABK69875.1 - 0.067 12.1 0.0 0.093 11.6 0.0 1.5 1 1 0 1 1 1 0 Diacylglycerol acyltransferase CoA_transf_3 PF02515.17 ABK69876.1 - 3.6e-115 385.0 0.0 4.1e-115 384.8 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Glyco_hydro_4C PF11975.8 ABK69877.1 - 5.5e-48 163.8 0.0 7.8e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase C-terminal domain Glyco_hydro_4 PF02056.16 ABK69877.1 - 1.5e-39 135.5 0.0 2e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase Ldh_1_N PF00056.23 ABK69877.1 - 0.018 15.1 0.0 0.6 10.2 0.0 2.3 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain MFS_1 PF07690.16 ABK69878.1 - 2.4e-25 89.2 57.7 2.4e-25 89.2 57.7 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily ABC2_membrane PF01061.24 ABK69879.1 - 0.03 13.7 0.4 0.042 13.3 0.4 1.2 1 0 0 1 1 1 0 ABC-2 type transporter Phage_holin_3_6 PF07332.11 ABK69879.1 - 2.6 8.1 6.0 0.81 9.7 1.6 2.1 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III HAD PF12710.7 ABK69880.1 - 7.1e-29 101.5 0.2 1.2e-28 100.8 0.2 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ACT_6 PF13740.6 ABK69880.1 - 9.3e-20 70.4 0.7 7.9e-18 64.2 0.5 2.8 2 0 0 2 2 2 1 ACT domain Hydrolase PF00702.26 ABK69880.1 - 1.9e-18 67.5 1.2 3.5e-18 66.7 1.2 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ABK69880.1 - 2.5e-13 50.4 0.0 2.6e-12 47.0 0.0 2.4 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase ACT PF01842.25 ABK69880.1 - 1.2e-07 31.3 1.0 0.00047 19.9 0.4 3.0 2 0 0 2 2 2 2 ACT domain S6PP PF05116.13 ABK69880.1 - 4.2e-06 26.5 0.0 6.4e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase HAD_2 PF13419.6 ABK69880.1 - 4.4e-06 26.9 0.0 0.00013 22.1 0.0 2.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 ABK69880.1 - 0.0028 17.1 0.0 0.094 12.1 0.0 2.1 2 0 0 2 2 2 1 Putative Phosphatase ACT_4 PF13291.6 ABK69880.1 - 0.056 14.0 0.0 0.85 10.3 0.0 2.4 2 0 0 2 2 2 0 ACT domain Hydrolase_like PF13242.6 ABK69880.1 - 0.12 12.4 2.9 0.48 10.5 0.1 2.6 2 0 0 2 2 2 0 HAD-hyrolase-like Xan_ur_permease PF00860.20 ABK69883.1 - 1.8e-82 277.2 45.5 2.4e-82 276.7 45.5 1.2 1 0 0 1 1 1 1 Permease family GHMP_kinases_N PF00288.26 ABK69883.1 - 0.044 14.0 1.1 0.044 14.0 1.1 2.4 2 0 0 2 2 2 0 GHMP kinases N terminal domain Usp PF00582.26 ABK69884.1 - 9.4e-41 139.6 9.8 1.4e-25 90.5 1.3 2.1 2 0 0 2 2 2 2 Universal stress protein family FR47 PF08445.10 ABK69884.1 - 0.068 13.1 0.6 0.29 11.1 0.3 2.1 2 0 0 2 2 2 0 FR47-like protein ECH_1 PF00378.20 ABK69885.1 - 4.1e-82 275.3 2.7 4.6e-82 275.1 2.7 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK69885.1 - 4e-37 128.5 3.5 4.2e-35 121.8 0.6 1.9 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase PAPS_reduct PF01507.19 ABK69886.1 - 1.3e-47 162.1 0.0 1.7e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.20 ABK69886.1 - 0.0084 15.9 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 PP-loop family Diphthami_syn_2 PF01902.17 ABK69886.1 - 0.084 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Diphthamide synthase QueC PF06508.13 ABK69886.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC HupF_HypC PF01455.18 ABK69887.1 - 3e-25 88.1 0.0 4.1e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 HupF/HypC family HycI PF01750.18 ABK69888.1 - 1.6e-12 47.3 0.0 2e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Hydrogenase maturation protease Nitrate_red_del PF02613.15 ABK69889.1 - 3.1e-09 37.0 0.0 4e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Nitrate reductase delta subunit DUF4233 PF14017.6 ABK69890.1 - 1.7e-28 99.0 14.6 2e-28 98.8 14.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4233) Fe-ADH PF00465.19 ABK69891.1 - 1.1e-105 353.4 0.2 1.3e-105 353.2 0.2 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 ABK69891.1 - 7.6e-14 52.0 0.1 1e-07 31.9 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Transgly_assoc PF04226.13 ABK69892.1 - 9.9e-13 48.1 15.4 9.9e-13 48.1 15.4 2.4 2 1 0 2 2 2 1 Transglycosylase associated protein DUF5518 PF17647.1 ABK69892.1 - 0.0042 17.2 20.5 0.0049 17.0 20.5 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5518) Sarcolipin PF05366.11 ABK69892.1 - 0.24 11.1 3.4 0.48 10.2 3.4 1.5 1 0 0 1 1 1 0 Sarcolipin Rick_17kDa_Anti PF05433.15 ABK69892.1 - 0.27 11.1 16.4 0.094 12.6 1.6 2.5 1 1 1 2 2 2 0 Glycine zipper 2TM domain ABC2_membrane_2 PF12679.7 ABK69892.1 - 0.71 9.1 10.1 0.47 9.7 8.6 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein TMEM208_SND2 PF05620.11 ABK69892.1 - 1.2 8.9 4.2 2.2 8.0 0.2 2.0 1 1 1 2 2 2 0 SRP-independent targeting protein 2/TMEM208 DUF4231 PF14015.6 ABK69892.1 - 1.5 9.3 5.1 2.9 8.4 5.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) Peptidase_U4 PF03419.13 ABK69892.1 - 3 7.1 8.3 3.2 6.9 8.3 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA FeoB_C PF07664.12 ABK69892.1 - 6.1 6.6 12.8 1.4 8.7 0.3 3.0 2 1 1 3 3 3 0 Ferrous iron transport protein B C terminus adh_short_C2 PF13561.6 ABK69893.1 - 4.1e-53 180.4 1.4 5e-53 180.1 1.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK69893.1 - 1.3e-45 155.2 0.0 1.6e-45 155.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK69893.1 - 8e-12 45.4 0.1 1.3e-11 44.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK69893.1 - 0.00011 21.8 0.0 0.00022 20.8 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AA_permease_2 PF13520.6 ABK69895.1 - 3.2e-35 121.8 42.5 4.8e-35 121.2 42.4 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ABK69895.1 - 2.6e-22 79.1 40.7 4e-22 78.5 40.7 1.2 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.16 ABK69896.1 - 1.8e-27 96.2 84.5 2.3e-26 92.5 50.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK69896.1 - 4.8e-27 94.9 32.8 1.5e-25 90.0 31.6 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 ABK69896.1 - 0.0006 18.4 3.2 0.0006 18.4 3.2 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 ABK69896.1 - 0.0061 14.9 5.9 0.023 13.0 0.2 2.4 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 ABK69896.1 - 0.024 13.2 34.6 0.0086 14.7 9.4 3.0 1 1 1 2 2 2 0 MFS/sugar transport protein FCD PF07729.12 ABK69897.1 - 3.9e-25 88.7 9.6 7.7e-25 87.7 9.6 1.5 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 ABK69897.1 - 7.6e-14 51.1 0.2 1.7e-13 50.0 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family TrmB PF01978.19 ABK69897.1 - 0.0053 16.6 0.1 0.014 15.3 0.1 1.8 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 ABK69897.1 - 0.029 14.3 0.1 0.1 12.5 0.1 2.0 1 0 0 1 1 1 0 MarR family HTH_11 PF08279.12 ABK69897.1 - 0.051 13.5 0.0 0.096 12.7 0.0 1.5 1 0 0 1 1 1 0 HTH domain ClpB_D2-small PF10431.9 ABK69897.1 - 0.067 13.2 0.0 0.25 11.4 0.0 2.0 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein HTH_27 PF13463.6 ABK69897.1 - 0.076 13.5 0.0 0.21 12.1 0.0 1.8 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_24 PF13412.6 ABK69897.1 - 0.095 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_15 PF12324.8 ABK69897.1 - 0.1 12.6 0.1 0.25 11.3 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase Fe_dep_repress PF01325.19 ABK69897.1 - 0.1 12.8 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain RuvA_N PF01330.21 ABK69898.1 - 4.8e-20 71.4 0.1 1.6e-19 69.8 0.1 1.8 2 0 0 2 2 2 1 RuvA N terminal domain HHH_5 PF14520.6 ABK69898.1 - 1.4e-16 60.8 0.1 5e-16 59.0 0.1 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain RuvA_C PF07499.13 ABK69898.1 - 1.6e-11 44.4 2.9 2.3e-11 44.0 0.5 2.2 2 0 0 2 2 2 1 RuvA, C-terminal domain HHH PF00633.23 ABK69898.1 - 0.0016 18.2 0.2 0.59 10.1 0.1 2.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_3 PF12836.7 ABK69898.1 - 0.022 15.0 0.0 0.28 11.4 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif HHH_2 PF12826.7 ABK69898.1 - 0.043 13.9 0.0 0.18 11.9 0.0 2.0 1 1 0 1 1 1 0 Helix-hairpin-helix motif HHH_8 PF14716.6 ABK69898.1 - 0.089 13.2 0.1 3.8 8.0 0.0 2.7 3 0 0 3 3 3 0 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 ABK69898.1 - 0.15 11.9 0.1 8.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda MMPL PF03176.15 ABK69899.1 - 4.3e-209 693.2 24.6 1.6e-105 352.7 6.6 2.4 2 0 0 2 2 2 2 MMPL family HTH_23 PF13384.6 ABK69900.1 - 0.018 14.8 0.1 0.018 14.8 0.1 2.3 3 0 0 3 3 3 0 Homeodomain-like domain TetR_N PF00440.23 ABK69900.1 - 0.028 14.2 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family Cep57_CLD_2 PF14197.6 ABK69900.1 - 0.031 14.4 4.2 0.11 12.6 4.2 1.9 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 HTH_22 PF13309.6 ABK69900.1 - 0.09 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 HTH domain ADIP PF11559.8 ABK69900.1 - 0.21 11.7 7.5 0.42 10.7 7.5 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding KfrA_N PF11740.8 ABK69900.1 - 0.43 11.3 9.1 0.76 10.5 9.1 1.5 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term FUSC PF04632.12 ABK69900.1 - 3.7 6.0 11.3 4.4 5.7 11.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family HTH_31 PF13560.6 ABK69900.1 - 6.4 7.2 12.9 0.13 12.6 1.7 3.3 2 2 1 3 3 3 0 Helix-turn-helix domain PAS_9 PF13426.7 ABK69901.1 - 0.00066 19.9 0.0 0.00067 19.9 0.0 1.1 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 ABK69901.1 - 0.0073 16.5 0.0 0.0074 16.5 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 ABK69901.1 - 0.018 15.0 0.0 0.023 14.7 0.0 1.3 1 1 0 1 1 1 0 PAS fold PAS_8 PF13188.7 ABK69901.1 - 0.082 13.0 0.0 0.12 12.4 0.0 1.6 1 1 0 1 1 1 0 PAS domain MMPL PF03176.15 ABK69902.1 - 3.4e-172 571.9 39.1 7.1e-92 307.9 11.6 3.3 2 1 1 3 3 3 2 MMPL family PhageMin_Tail PF10145.9 ABK69902.1 - 0.0054 16.6 1.7 0.0054 16.6 1.7 3.3 4 1 0 4 4 4 1 Phage-related minor tail protein GTP_CH_N PF12471.8 ABK69902.1 - 0.034 13.9 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 GTP cyclohydrolase N terminal ACR_tran PF00873.19 ABK69902.1 - 0.045 11.4 25.4 0.029 12.0 5.6 2.4 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family Laminin_II PF06009.12 ABK69902.1 - 0.23 11.5 3.0 8.9 6.3 1.0 2.5 2 0 0 2 2 2 0 Laminin Domain II DUF2564 PF10819.8 ABK69902.1 - 0.24 11.8 2.1 14 6.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2564) DUF1090 PF06476.12 ABK69902.1 - 0.34 11.0 1.0 0.55 10.4 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) Prominin PF05478.11 ABK69902.1 - 0.49 8.3 1.6 3.6 5.4 0.3 2.4 2 0 0 2 2 2 0 Prominin Inositol_P PF00459.25 ABK69903.1 - 1.1e-46 159.6 0.4 1.3e-46 159.3 0.4 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 ABK69903.1 - 0.061 12.8 0.0 0.098 12.1 0.0 1.2 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain Ni_hydr_CYTB PF01292.20 ABK69904.1 - 0.0012 18.5 1.0 0.01 15.5 0.1 2.1 2 0 0 2 2 2 1 Prokaryotic cytochrome b561 TPPK_C PF12555.8 ABK69904.1 - 0.006 16.6 3.7 0.016 15.2 3.7 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphokinase C terminal URO-D PF01208.17 ABK69905.1 - 2.8e-120 401.6 0.0 3.1e-120 401.5 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) zf-CpG_bind_C PF12269.8 ABK69906.1 - 0.075 12.8 0.0 0.08 12.7 0.0 1.0 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain DUF190 PF02641.15 ABK69907.1 - 3.3e-61 203.7 0.1 9.5e-19 67.5 0.0 3.0 3 0 0 3 3 3 3 Uncharacterized ACR, COG1993 A_deaminase PF00962.22 ABK69908.1 - 4e-102 341.9 0.0 4.8e-102 341.6 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase ROK PF00480.20 ABK69909.1 - 8.2e-50 169.9 0.0 9.6e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 ROK family MarR_2 PF12802.7 ABK69909.1 - 1.1e-05 25.2 0.8 1.1e-05 25.2 0.8 2.0 2 0 0 2 2 2 1 MarR family HTH_AsnC-type PF13404.6 ABK69909.1 - 4.5e-05 23.2 6.1 0.002 17.9 1.5 2.9 3 0 0 3 3 3 2 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 ABK69909.1 - 7e-05 22.3 0.0 0.00032 20.2 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 ABK69909.1 - 0.00061 19.8 0.3 0.0017 18.4 0.3 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 ABK69909.1 - 0.015 15.3 0.1 0.028 14.4 0.1 1.4 1 0 0 1 1 1 0 HTH domain HTH_IclR PF09339.10 ABK69909.1 - 0.049 13.5 2.1 0.48 10.3 0.4 2.5 2 0 0 2 2 2 0 IclR helix-turn-helix domain MarR PF01047.22 ABK69909.1 - 0.067 13.1 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 MarR family SHOCT PF09851.9 ABK69910.1 - 2.7e-06 26.9 1.0 5.9e-06 25.9 1.0 1.6 1 0 0 1 1 1 1 Short C-terminal domain CarS-like PF01864.17 ABK69911.1 - 0.21 11.6 0.0 0.23 11.4 0.0 1.0 1 0 0 1 1 1 0 CDP-archaeol synthase His_Phos_1 PF00300.22 ABK69912.1 - 3.6e-59 199.7 0.9 3.6e-59 199.7 0.9 1.4 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) RVT_3 PF13456.6 ABK69912.1 - 5.9e-25 87.5 0.5 3.6e-24 85.0 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase-like RNase_H PF00075.24 ABK69912.1 - 4.8e-10 39.8 0.0 1.2e-09 38.5 0.0 1.6 1 1 0 1 1 1 1 RNase H Oxidored_q6 PF01058.22 ABK69913.1 - 6.5e-22 77.8 0.0 8.8e-22 77.3 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit GCV_H PF01597.19 ABK69914.1 - 1e-40 138.4 0.0 1.1e-40 138.3 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein APH_6_hur PF04655.14 ABK69915.1 - 2.6e-46 158.1 2.3 3.1e-46 157.8 2.3 1.1 1 0 0 1 1 1 1 Aminoglycoside/hydroxyurea antibiotic resistance kinase Fructosamin_kin PF03881.14 ABK69915.1 - 0.15 11.2 0.1 0.22 10.7 0.1 1.1 1 0 0 1 1 1 0 Fructosamine kinase SnoaL_4 PF13577.6 ABK69916.1 - 2.6e-17 63.2 0.2 5e-17 62.2 0.2 1.5 1 1 0 1 1 1 1 SnoaL-like domain Ring_hydroxyl_B PF00866.18 ABK69916.1 - 6.3e-05 23.1 0.1 9.9e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Ring hydroxylating beta subunit adh_short_C2 PF13561.6 ABK69917.1 - 2.7e-43 148.2 5.8 3.7e-43 147.8 5.8 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK69917.1 - 4.3e-41 140.5 5.1 8e-41 139.6 3.6 2.1 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 ABK69917.1 - 4.3e-10 39.8 3.9 6e-08 32.8 3.9 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK69917.1 - 0.00018 21.0 1.3 0.00036 20.1 1.3 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family LytR_C PF13399.6 ABK69917.1 - 0.0011 19.9 2.3 0.018 16.0 1.9 2.7 2 1 0 2 2 2 1 LytR cell envelope-related transcriptional attenuator PFOR_II PF17147.4 ABK69917.1 - 0.04 14.2 0.6 0.04 14.2 0.6 2.1 2 0 0 2 2 2 0 Pyruvate:ferredoxin oxidoreductase core domain II Glyco_transf_4 PF13439.6 ABK69917.1 - 0.056 13.4 0.5 2.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase Family 4 SCP_3 PF17844.1 ABK69918.1 - 2e-39 133.3 2.0 2.8e-39 132.8 2.0 1.2 1 0 0 1 1 1 1 Bacterial SCP ortholog TetR_N PF00440.23 ABK69919.1 - 1.6e-16 59.8 0.0 6.7e-10 38.6 0.0 2.5 2 0 0 2 2 2 2 Bacterial regulatory proteins, tetR family TetR_C_13 PF16925.5 ABK69919.1 - 2.8e-13 49.8 0.0 2.7e-08 33.7 0.0 2.4 2 0 0 2 2 2 2 Tetracyclin repressor-like, C-terminal domain TetR_C_6 PF13977.6 ABK69919.1 - 8e-07 29.3 2.7 0.00012 22.3 0.2 2.8 2 0 0 2 2 2 2 BetI-type transcriptional repressor, C-terminal TetR_C_25 PF17933.1 ABK69919.1 - 7.3e-05 23.0 0.0 0.038 14.3 0.0 2.6 2 0 0 2 2 2 2 Tetracyclin repressor-like, C-terminal domain TetR_C_11 PF16859.5 ABK69919.1 - 0.0015 18.8 1.6 0.067 13.5 0.1 2.9 3 0 0 3 3 3 1 Tetracyclin repressor-like, C-terminal domain HTH_31 PF13560.6 ABK69919.1 - 0.0081 16.5 0.7 4.6 7.7 0.1 3.0 2 1 0 2 2 2 2 Helix-turn-helix domain Esterase PF00756.20 ABK69920.1 - 2.2e-67 227.3 0.8 2.6e-67 227.1 0.8 1.1 1 0 0 1 1 1 1 Putative esterase Methyltransf_11 PF08241.12 ABK69923.1 - 1.2e-22 80.3 0.0 1.8e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABK69923.1 - 5.7e-20 71.8 0.0 8.9e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABK69923.1 - 5.7e-14 52.3 0.0 2.1e-13 50.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK69923.1 - 1.5e-13 51.3 0.0 2.1e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ABK69923.1 - 3.7e-12 46.1 0.0 7e-11 41.9 0.0 2.0 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 ABK69923.1 - 1.5e-09 37.8 0.0 2e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ABK69923.1 - 0.00015 21.3 0.1 0.00078 19.0 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 ABK69923.1 - 0.00027 20.0 0.0 0.00033 19.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) FtsJ PF01728.19 ABK69923.1 - 0.00045 20.4 0.0 0.0016 18.5 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.20 ABK69923.1 - 0.00054 19.3 0.0 0.0012 18.2 0.0 1.5 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 ABK69923.1 - 0.0014 17.9 0.1 0.004 16.5 0.1 1.7 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_8 PF05148.15 ABK69923.1 - 0.012 15.5 0.0 0.089 12.6 0.0 2.0 1 1 0 1 1 1 0 Hypothetical methyltransferase TetR_C_16 PF17920.1 ABK69924.1 - 4.9e-31 107.1 0.5 8.7e-31 106.3 0.5 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK69924.1 - 7.8e-15 54.4 0.5 7.8e-15 54.4 0.5 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family E3_binding PF02817.17 ABK69924.1 - 0.0064 16.8 0.3 6.1 7.3 0.0 3.2 3 0 0 3 3 3 1 e3 binding domain DmpG_comm PF07836.11 ABK69924.1 - 0.05 13.1 0.3 0.52 9.9 0.1 2.1 2 0 0 2 2 2 0 DmpG-like communication domain HTH_23 PF13384.6 ABK69924.1 - 0.076 12.8 0.1 2.7 7.9 0.0 2.9 3 0 0 3 3 3 0 Homeodomain-like domain WIYLD PF10440.9 ABK69924.1 - 0.15 11.9 0.1 0.36 10.7 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-binding WIYLD domain ABC_tran PF00005.27 ABK69925.1 - 5.4e-30 104.7 0.0 7e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK69925.1 - 5.4e-12 46.1 0.3 3.6e-05 23.7 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ABK69925.1 - 2.8e-05 23.8 0.0 5.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 ABK69925.1 - 3.1e-05 23.5 0.1 0.0042 16.6 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ABK69925.1 - 0.00089 19.8 0.0 0.0012 19.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ABK69925.1 - 0.0022 18.4 0.0 0.0025 18.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 ABK69925.1 - 0.0028 17.6 0.1 0.0042 17.0 0.1 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 ABK69925.1 - 0.0068 16.2 0.0 0.012 15.3 0.0 1.4 2 0 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 ABK69925.1 - 0.013 14.8 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 ABK69925.1 - 0.015 15.0 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ABK69925.1 - 0.018 15.0 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_27 PF13514.6 ABK69925.1 - 0.026 14.1 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 ABK69925.1 - 0.035 13.3 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain MMR_HSR1 PF01926.23 ABK69925.1 - 0.036 14.1 0.1 0.066 13.3 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase MCM PF00493.23 ABK69925.1 - 0.055 12.6 0.0 0.085 11.9 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_33 PF13671.6 ABK69925.1 - 0.062 13.5 0.0 0.094 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 ABK69925.1 - 0.069 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ABK69925.1 - 0.097 12.2 0.0 0.67 9.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 ABK69925.1 - 0.17 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 ABK69925.1 - 0.17 11.3 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 ABK69926.1 - 1.1e-34 119.9 0.0 3e-34 118.5 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 ABK69926.1 - 5.6e-07 29.7 0.1 0.0035 17.2 0.1 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ABK69926.1 - 5.5e-06 26.9 0.4 7.4e-05 23.2 0.0 2.6 1 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 ABK69926.1 - 0.00023 21.6 0.7 0.0047 17.4 0.0 2.9 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ABK69926.1 - 0.00056 20.2 0.2 0.011 16.0 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 ABK69926.1 - 0.00065 19.5 0.2 0.0055 16.4 0.0 2.5 2 1 2 4 4 4 1 AAA domain Rad17 PF03215.15 ABK69926.1 - 0.0012 18.8 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_29 PF13555.6 ABK69926.1 - 0.0031 17.2 0.6 0.042 13.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 ABK69926.1 - 0.0042 16.4 0.5 0.013 14.8 0.0 2.0 3 0 0 3 3 2 1 Zeta toxin AAA_5 PF07728.14 ABK69926.1 - 0.0049 16.9 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 ABK69926.1 - 0.0073 15.9 0.4 0.047 13.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ABK69926.1 - 0.014 15.6 0.0 0.035 14.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 ABK69926.1 - 0.016 14.9 0.0 0.04 13.5 0.0 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 ABK69926.1 - 0.018 15.5 0.0 0.035 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ABK69926.1 - 0.026 14.9 0.0 0.06 13.7 0.0 1.7 2 0 0 2 2 1 0 RNA helicase AAA_24 PF13479.6 ABK69926.1 - 0.031 14.0 0.4 0.14 11.9 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ABK69926.1 - 0.034 13.6 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region CBS PF00571.28 ABK69926.1 - 0.041 14.3 0.3 0.16 12.5 0.2 2.1 2 0 0 2 2 1 0 CBS domain AAA_15 PF13175.6 ABK69926.1 - 0.044 13.5 0.0 0.064 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 ABK69926.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase tRNA_lig_kinase PF08303.11 ABK69926.1 - 0.059 13.5 0.2 0.43 10.6 0.0 2.4 3 0 0 3 3 3 0 tRNA ligase kinase domain NB-ARC PF00931.22 ABK69926.1 - 0.064 12.4 0.1 0.17 11.0 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 ABK69926.1 - 0.074 13.6 0.1 0.45 11.1 0.0 2.3 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 ABK69926.1 - 0.079 12.7 0.2 0.14 11.9 0.2 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 ABK69926.1 - 0.099 12.5 0.1 0.47 10.3 0.1 2.2 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 ABK69926.1 - 0.1 12.7 0.0 0.37 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 ABK69926.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit PRK PF00485.18 ABK69926.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Sulfate_transp PF00916.20 ABK69927.1 - 1.9e-48 165.2 29.5 1.5e-25 89.8 4.5 2.1 1 1 1 2 2 2 2 Sulfate permease family STAS PF01740.21 ABK69927.1 - 9.6e-07 28.4 0.0 1.8e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain adh_short PF00106.25 ABK69928.1 - 1.9e-32 112.3 0.0 2.7e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK69928.1 - 8.8e-18 64.7 1.4 1.1e-17 64.4 1.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK69928.1 - 9.7e-08 32.1 2.5 2.9e-07 30.6 2.5 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK69928.1 - 0.00091 18.8 0.1 0.0072 15.8 0.1 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family FAD_binding_3 PF01494.19 ABK69928.1 - 0.0021 17.4 0.1 0.0036 16.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.18 ABK69928.1 - 0.059 13.2 0.2 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 ABK69928.1 - 0.35 10.7 2.9 0.28 11.1 0.4 1.9 2 0 0 2 2 2 0 NAD(P)H-binding ABC_tran PF00005.27 ABK69929.1 - 8.5e-49 165.6 0.0 1.9e-28 99.7 0.0 2.1 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ABK69929.1 - 1e-11 45.2 1.4 0.0013 18.6 0.2 3.1 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ABK69929.1 - 0.00055 19.9 0.1 0.0015 18.5 0.1 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 ABK69929.1 - 0.019 14.7 2.1 0.057 13.2 0.1 2.6 3 0 0 3 3 3 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ABK69929.1 - 0.036 14.2 0.0 0.16 12.1 0.0 2.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 ABK69929.1 - 0.055 13.0 4.4 1 8.9 0.3 2.7 3 0 0 3 3 3 0 AAA domain SMC_N PF02463.19 ABK69929.1 - 0.056 12.9 0.8 5.1 6.5 0.0 3.0 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_13 PF13166.6 ABK69929.1 - 0.096 11.3 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 ABK69929.1 - 0.21 10.3 1.3 28 3.3 0.0 3.4 3 1 0 3 3 3 0 Predicted ATPase of the ABC class AAA_23 PF13476.6 ABK69929.1 - 0.23 12.0 0.0 0.5 10.8 0.0 1.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 ABK69929.1 - 0.26 11.8 0.5 25 5.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 ABK69929.1 - 0.91 9.2 10.4 1.1 8.9 3.7 3.5 3 1 0 3 3 3 0 AAA domain AAA_16 PF13191.6 ABK69929.1 - 1.5 9.2 4.0 4.1 7.8 1.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain Tic110 PF16940.5 ABK69930.1 - 0.056 11.9 0.6 0.064 11.7 0.6 1.0 1 0 0 1 1 1 0 Chloroplast envelope transporter DUF3618 PF12277.8 ABK69931.1 - 2.4e-15 56.5 7.1 2.4e-15 56.5 7.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3618) Trp_oprn_chp PF09534.10 ABK69931.1 - 0.0026 17.6 2.5 0.0031 17.3 2.5 1.1 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF883 PF05957.13 ABK69931.1 - 0.17 12.5 10.3 0.46 11.1 10.3 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) SKG6 PF08693.10 ABK69931.1 - 0.19 11.2 6.2 0.34 10.4 6.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain YtxH PF12732.7 ABK69931.1 - 0.32 11.6 4.8 0.63 10.6 4.8 1.5 1 0 0 1 1 1 0 YtxH-like protein SHOCT PF09851.9 ABK69932.1 - 4.5e-07 29.4 1.8 7.7e-07 28.7 1.8 1.4 1 0 0 1 1 1 1 Short C-terminal domain PLDc_N PF13396.6 ABK69932.1 - 5.7e-06 26.2 6.8 5.7e-06 26.2 6.8 2.0 1 1 1 2 2 2 1 Phospholipase_D-nuclease N-terminal DUF1980 PF09323.10 ABK69932.1 - 0.074 13.0 0.9 0.1 12.5 0.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1980) DUF2207 PF09972.9 ABK69932.1 - 0.2 10.4 0.7 0.22 10.2 0.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2208 PF09973.9 ABK69932.1 - 0.23 11.1 0.8 0.31 10.6 0.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) Trm112p PF03966.16 ABK69933.1 - 7e-08 32.9 1.2 5.8e-07 30.0 0.5 2.3 2 1 0 2 2 2 1 Trm112p-like protein ACP PF06857.11 ABK69936.1 - 1.3e-19 70.2 0.1 1.6e-19 69.9 0.1 1.1 1 0 0 1 1 1 1 Malonate decarboxylase delta subunit (MdcD) GerE PF00196.19 ABK69937.1 - 4.2e-07 29.4 0.0 5e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 ABK69937.1 - 0.0015 18.2 0.1 0.012 15.3 0.1 2.3 2 1 0 2 2 2 1 Sigma-70, region 4 HTH_30 PF13556.6 ABK69937.1 - 0.0018 18.0 0.1 0.0024 17.6 0.1 1.2 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_23 PF13384.6 ABK69937.1 - 0.0055 16.5 0.2 0.012 15.4 0.1 1.7 1 1 0 1 1 1 1 Homeodomain-like domain Sigma70_r4 PF04545.16 ABK69937.1 - 0.033 13.7 0.1 0.08 12.5 0.1 1.6 1 1 0 1 1 1 0 Sigma-70, region 4 HTH_24 PF13412.6 ABK69937.1 - 0.076 12.6 0.0 0.32 10.6 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_32 PF13565.6 ABK69937.1 - 0.21 12.2 5.2 2.6 8.7 1.2 2.1 1 1 1 2 2 2 0 Homeodomain-like domain Ribosomal_L19 PF01245.20 ABK69938.1 - 8.7e-51 170.5 0.6 9.5e-51 170.4 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L19 SatD PF16264.5 ABK69939.1 - 1.9e-14 53.8 0.0 2.8e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 SatD family (SatD) Methyltransf_25 PF13649.6 ABK69940.1 - 5.4e-16 59.1 0.0 8.3e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK69940.1 - 2.5e-15 57.0 0.0 3.9e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABK69940.1 - 3.9e-14 53.1 0.1 1.5e-13 51.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABK69940.1 - 7.4e-13 48.7 0.0 9.4e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 ABK69940.1 - 8.5e-12 45.1 0.0 1.2e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_31 PF13847.6 ABK69940.1 - 1.5e-10 41.0 0.0 2e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 ABK69940.1 - 1.2e-06 27.8 0.0 1.4e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.14 ABK69940.1 - 2.3e-06 27.2 0.0 4.2e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 ABK69940.1 - 0.0004 20.0 0.0 0.00061 19.4 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 ABK69940.1 - 0.012 15.6 0.0 0.017 15.2 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 ABK69940.1 - 0.05 13.0 0.0 0.06 12.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.12 ABK69940.1 - 0.06 12.4 0.0 0.078 12.1 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase Crystallin PF00525.18 ABK69940.1 - 0.076 13.2 0.1 0.5 10.6 0.0 2.3 3 0 0 3 3 3 0 Alpha crystallin A chain, N terminal Methyltransf_9 PF08003.11 ABK69940.1 - 0.098 11.6 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) CMAS PF02353.20 ABK69940.1 - 0.12 11.6 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase SnoaL_4 PF13577.6 ABK69941.1 - 3.7e-21 75.6 0.0 4.6e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DDE_Tnp_ISL3 PF01610.17 ABK69943.1 - 3.1e-50 171.1 0.0 4.4e-50 170.6 0.0 1.2 1 0 0 1 1 1 1 Transposase zf-ISL3 PF14690.6 ABK69943.1 - 4e-11 43.4 7.4 5.2e-10 39.8 4.3 2.9 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HTH_Tnp_ISL3 PF13542.6 ABK69943.1 - 3.4e-10 39.2 0.3 3.4e-10 39.2 0.3 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain of transposase family ISL3 Carboxyl_trans PF01039.22 ABK69944.1 - 8.9e-75 252.2 0.0 1.2e-74 251.8 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain ACCA PF03255.14 ABK69944.1 - 0.0047 16.8 0.0 0.014 15.3 0.0 1.7 2 0 0 2 2 2 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit ECH_1 PF00378.20 ABK69944.1 - 0.0055 16.1 2.8 0.084 12.2 0.4 3.3 3 1 0 3 3 3 1 Enoyl-CoA hydratase/isomerase Abhydrolase_1 PF00561.20 ABK69947.1 - 6.6e-31 107.9 0.0 1.2e-28 100.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK69947.1 - 5e-20 73.1 10.1 6.6e-20 72.7 10.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK69947.1 - 2e-16 60.0 0.8 4.2e-16 58.9 0.1 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 ABK69947.1 - 2.5e-05 23.1 0.0 2.8e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.10 ABK69947.1 - 0.00011 22.3 0.0 0.00033 20.7 0.1 1.8 2 0 0 2 2 2 1 TAP-like protein Thioesterase PF00975.20 ABK69947.1 - 0.0029 17.8 0.0 0.0076 16.4 0.0 1.7 1 1 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 ABK69947.1 - 0.0052 16.5 0.1 0.014 15.1 0.0 1.5 1 1 0 2 2 2 1 Putative esterase UPF0227 PF05728.12 ABK69947.1 - 0.049 13.6 0.0 0.07 13.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PsbI PF02532.14 ABK69947.1 - 0.053 13.5 0.7 0.86 9.6 0.1 2.4 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) FSH1 PF03959.13 ABK69947.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DLH PF01738.18 ABK69947.1 - 0.14 11.7 0.0 14 5.1 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 ABK69947.1 - 0.2 11.4 0.0 3 7.6 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF2561 PF10812.8 ABK69948.1 - 0.0001 22.4 5.5 0.00014 22.0 5.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2561) Neur_chan_memb PF02932.16 ABK69948.1 - 0.00023 21.3 0.6 0.00026 21.1 0.6 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S49_N PF08496.10 ABK69948.1 - 0.00058 19.9 1.3 0.00073 19.6 1.3 1.2 1 0 0 1 1 1 1 Peptidase family S49 N-terminal DUF4636 PF15468.6 ABK69948.1 - 0.0019 17.9 0.3 0.01 15.6 0.3 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4636) TMEM51 PF15345.6 ABK69948.1 - 0.0036 17.2 1.0 0.0041 17.0 1.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 Shisa PF13908.6 ABK69948.1 - 0.008 16.4 0.1 0.0095 16.2 0.1 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator V_ATPase_I PF01496.19 ABK69948.1 - 0.015 13.3 0.4 0.018 13.0 0.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sigma_reg_N PF13800.6 ABK69948.1 - 0.015 15.6 0.2 0.022 15.0 0.2 1.3 1 0 0 1 1 1 0 Sigma factor regulator N-terminal MAP17 PF15807.5 ABK69948.1 - 0.026 14.8 2.6 0.039 14.2 2.4 1.5 1 1 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF4064 PF13273.6 ABK69948.1 - 0.026 14.8 0.5 0.043 14.1 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF4307 PF14155.6 ABK69948.1 - 0.03 14.1 2.2 0.044 13.6 2.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4307) IgaA PF07095.11 ABK69948.1 - 0.031 12.3 1.4 0.035 12.1 1.4 1.0 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA DUF4446 PF14584.6 ABK69948.1 - 0.051 13.6 0.6 0.072 13.1 0.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) DUF420 PF04238.12 ABK69948.1 - 0.055 13.8 1.5 0.083 13.2 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF420) BT1 PF03092.16 ABK69948.1 - 0.065 11.4 1.6 0.08 11.2 1.6 1.0 1 0 0 1 1 1 0 BT1 family DUF4381 PF14316.6 ABK69948.1 - 0.071 13.4 9.4 0.14 12.4 9.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4381) DUF3052 PF11253.8 ABK69948.1 - 0.09 12.7 1.5 0.25 11.2 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3052) DAG1 PF05454.11 ABK69948.1 - 0.14 11.5 0.2 0.19 11.1 0.2 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) SID-1_RNA_chan PF13965.6 ABK69948.1 - 0.14 10.6 0.3 0.15 10.5 0.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FixQ PF05545.11 ABK69948.1 - 0.16 11.9 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Serinc PF03348.15 ABK69948.1 - 0.19 10.6 0.6 0.22 10.4 0.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4834 PF16118.5 ABK69948.1 - 0.24 12.4 4.0 1.1 10.2 4.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) SHR3_chaperone PF08229.11 ABK69948.1 - 0.25 10.3 1.7 0.23 10.4 0.1 1.7 1 1 1 2 2 2 0 ER membrane protein SH3 EphA2_TM PF14575.6 ABK69948.1 - 0.27 12.2 2.5 0.44 11.5 2.5 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF5385 PF17359.2 ABK69948.1 - 0.28 10.7 4.1 0.1 12.1 0.7 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5385) LRR19-TM PF15176.6 ABK69948.1 - 0.46 10.5 2.5 0.66 10.0 0.3 2.0 1 1 1 2 2 2 0 Leucine-rich repeat family 19 TM domain OSTbeta PF15048.6 ABK69948.1 - 0.6 10.3 4.2 1.7 8.8 4.2 1.8 1 1 0 1 1 1 0 Organic solute transporter subunit beta protein Kei1 PF08552.11 ABK69948.1 - 1.1 9.1 4.4 1.4 8.7 4.3 1.3 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 CoA_binding_3 PF13727.6 ABK69948.1 - 1.1 9.2 4.7 1.6 8.7 4.6 1.4 1 1 0 1 1 1 0 CoA-binding domain tRNA_anti-like PF12869.7 ABK69948.1 - 2.7 7.6 6.9 3.3 7.3 6.4 1.5 1 1 0 1 1 1 0 tRNA_anti-like Vpu PF00558.19 ABK69948.1 - 5.1 6.9 6.0 7.8 6.3 6.0 1.5 1 1 0 1 1 1 0 Vpu protein Peptidase_M24 PF00557.24 ABK69949.1 - 1.9e-26 93.0 0.2 2.5e-26 92.7 0.2 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 ABK69949.1 - 9.7e-06 26.3 0.0 2.2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain ArsB PF02040.15 ABK69950.1 - 4.6e-32 111.9 23.3 6.7e-32 111.3 23.3 1.2 1 1 0 1 1 1 1 Arsenical pump membrane protein CitMHS PF03600.16 ABK69950.1 - 4.3e-14 52.4 33.7 8.8e-14 51.4 33.7 1.5 1 0 0 1 1 1 1 Citrate transporter PufQ PF05398.11 ABK69950.1 - 0.13 12.4 3.2 0.17 12.0 0.5 2.6 2 0 0 2 2 2 0 PufQ cytochrome subunit FCD PF07729.12 ABK69951.1 - 8.1e-21 74.7 8.7 1.5e-20 73.9 8.7 1.4 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 ABK69951.1 - 9.1e-12 44.5 0.7 1.9e-11 43.4 0.7 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_CodY PF08222.11 ABK69951.1 - 0.00042 19.8 0.8 0.00093 18.7 0.8 1.5 1 0 0 1 1 1 1 CodY helix-turn-helix domain TrmB PF01978.19 ABK69951.1 - 0.0066 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 ABK69951.1 - 0.013 15.8 0.0 0.026 14.9 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator MarR_2 PF12802.7 ABK69951.1 - 0.073 13.0 0.5 0.28 11.1 0.1 2.2 2 0 0 2 2 2 0 MarR family HTH_Crp_2 PF13545.6 ABK69951.1 - 0.098 12.6 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_11 PF08279.12 ABK69951.1 - 0.15 12.0 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 HTH domain Methyltransf_11 PF08241.12 ABK69952.1 - 2.5e-23 82.6 0.0 7.1e-23 81.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABK69952.1 - 3.1e-20 72.7 0.1 1.5e-19 70.5 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABK69952.1 - 1.1e-16 61.0 0.0 2.1e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABK69952.1 - 3.3e-13 49.8 0.0 7.7e-13 48.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK69952.1 - 5.4e-13 49.5 0.1 1.5e-12 48.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 ABK69952.1 - 7.8e-12 45.0 0.0 1.4e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 ABK69952.1 - 3e-06 27.0 0.0 5.1e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) MetW PF07021.12 ABK69952.1 - 0.00076 19.1 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.15 ABK69952.1 - 0.0019 18.1 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_29 PF03141.16 ABK69952.1 - 0.0077 14.8 0.0 0.011 14.3 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 ABK69952.1 - 0.023 14.2 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 ABK69952.1 - 0.038 13.4 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF1524 PF07510.11 ABK69953.1 - 4e-13 49.4 0.0 5.2e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.6 ABK69953.1 - 1.8e-06 27.7 0.0 3.2e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease DUF3040 PF11239.8 ABK69954.1 - 0.13 12.6 11.7 0.16 12.3 11.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF2905 PF11146.8 ABK69954.1 - 0.68 10.2 16.2 0.15 12.3 5.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2905) PhaG_MnhG_YufB PF03334.14 ABK69954.1 - 0.78 10.0 10.0 1.3 9.4 1.3 2.1 1 1 1 2 2 2 0 Na+/H+ antiporter subunit DUF973 PF06157.11 ABK69954.1 - 0.86 8.6 7.9 0.88 8.6 7.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF2892 PF11127.8 ABK69954.1 - 0.96 9.5 9.6 1.4 9.0 9.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) DUF4337 PF14235.6 ABK69954.1 - 1.2 9.2 8.5 1.3 9.1 8.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF3784 PF12650.7 ABK69954.1 - 3.7 7.8 10.1 4.5 7.5 10.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) Aph-1 PF06105.12 ABK69954.1 - 5.2 6.4 10.0 5.9 6.2 10.0 1.0 1 0 0 1 1 1 0 Aph-1 protein Phage_holin_3_6 PF07332.11 ABK69955.1 - 0.064 13.3 6.2 0.067 13.2 6.2 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4131 PF13567.6 ABK69955.1 - 0.1 12.2 2.9 0.12 12.0 2.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) SirB PF04247.12 ABK69955.1 - 0.12 12.4 0.3 0.14 12.2 0.3 1.1 1 0 0 1 1 1 0 Invasion gene expression up-regulator, SirB DUF2371 PF10177.9 ABK69955.1 - 0.57 10.3 6.9 1.3 9.2 0.2 2.0 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) PetG PF02529.15 ABK69955.1 - 0.89 9.5 6.2 2.4 8.1 6.2 1.7 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 2TM PF13239.6 ABK69955.1 - 0.96 9.8 3.8 1.8 8.9 3.8 1.5 1 1 0 1 1 1 0 2TM domain TMEM174 PF15029.6 ABK69955.1 - 0.99 9.1 7.6 1.2 8.8 7.6 1.0 1 0 0 1 1 1 0 Transmembrane protein 174 Trp_oprn_chp PF09534.10 ABK69955.1 - 1.5 8.6 5.8 3.4 7.4 0.6 2.0 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF202 PF02656.15 ABK69955.1 - 1.9 9.0 6.0 4 8.0 6.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF2207 PF09972.9 ABK69955.1 - 2.1 7.0 4.3 2.1 7.0 4.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) BPD_transp_1 PF00528.22 ABK69956.1 - 2.9e-23 82.5 12.1 2.9e-23 82.5 12.1 2.2 1 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OATP PF03137.20 ABK69956.1 - 0.18 10.1 1.0 0.67 8.2 0.0 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Meth_synt_2 PF01717.18 ABK69957.1 - 4.6e-157 522.4 0.5 1.9e-153 510.5 0.1 2.3 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 ABK69957.1 - 8.4e-113 377.0 0.0 5.9e-108 361.1 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain ResB PF05140.14 ABK69958.1 - 8.7e-139 463.4 0.0 3.7e-138 461.4 0.0 1.8 1 1 0 1 1 1 1 ResB-like family Zip PF02535.22 ABK69958.1 - 7.7 5.6 6.0 9.7 5.3 0.1 2.4 3 0 0 3 3 3 0 ZIP Zinc transporter Cutinase PF01083.22 ABK69959.1 - 3.3e-16 59.7 0.2 6e-16 58.9 0.2 1.4 1 1 0 1 1 1 1 Cutinase PE-PPE PF08237.11 ABK69959.1 - 9.6e-07 28.6 0.0 1.7e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 PE-PPE domain DUF3089 PF11288.8 ABK69959.1 - 0.0035 16.9 0.1 0.0058 16.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) Abhydrolase_2 PF02230.16 ABK69959.1 - 0.011 15.6 0.0 0.038 13.8 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase VirJ PF06057.11 ABK69959.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Pantoate_transf PF02548.15 ABK69960.1 - 9.1e-104 346.4 0.5 1.1e-103 346.2 0.5 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 ABK69960.1 - 5.9e-06 25.9 1.9 1.7e-05 24.4 1.9 1.7 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase LapA_dom PF06305.11 ABK69962.1 - 9.3e-06 25.4 0.6 9.3e-06 25.4 0.6 1.7 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain Pox_A14 PF05767.12 ABK69962.1 - 0.067 13.4 0.6 0.075 13.2 0.6 1.1 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF2663 PF10864.8 ABK69962.1 - 0.22 11.9 0.3 0.24 11.8 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) DUF4051 PF13260.6 ABK69962.1 - 1.5 8.6 7.4 2.5 7.9 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) DUF4131 PF13567.6 ABK69962.1 - 2.4 7.8 7.7 1.1 8.9 0.5 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF1970 PF09301.10 ABK69962.1 - 8.3 6.7 7.1 1.2 9.5 2.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1970) Methyltransf_11 PF08241.12 ABK69963.1 - 3.2e-13 50.1 0.0 5.3e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABK69963.1 - 1.5e-09 38.5 0.0 2.4e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABK69963.1 - 2.9e-06 27.2 0.0 6.1e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK69963.1 - 3e-05 24.7 0.0 5.6e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABK69963.1 - 9.1e-05 22.3 0.0 0.00029 20.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ABK69963.1 - 0.0049 16.2 0.0 0.012 15.0 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 ABK69963.1 - 0.1 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF1794 PF08768.11 ABK69964.1 - 9.8e-45 152.1 0.1 1.2e-44 151.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) Rieske PF00355.26 ABK69965.1 - 2.2e-18 65.9 0.1 4.2e-18 65.1 0.1 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Fer2 PF00111.27 ABK69966.1 - 1e-10 41.4 0.6 1.8e-10 40.7 0.6 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.21 ABK69966.1 - 8.7e-09 36.0 0.0 1.8e-06 28.6 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 ABK69966.1 - 0.0075 16.4 0.4 0.062 13.4 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Fer2_3 PF13085.6 ABK69966.1 - 0.097 12.7 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain DUF664 PF04978.12 ABK69967.1 - 5e-46 156.8 0.3 5.7e-46 156.7 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF664) DinB_2 PF12867.7 ABK69967.1 - 1.6e-07 31.9 0.3 2.1e-07 31.5 0.3 1.2 1 0 0 1 1 1 1 DinB superfamily DinB PF05163.12 ABK69967.1 - 0.00012 22.1 0.0 0.00017 21.6 0.0 1.2 1 0 0 1 1 1 1 DinB family MDMPI_N PF11716.8 ABK69967.1 - 0.0012 19.5 1.4 0.002 18.9 1.4 1.3 1 0 0 1 1 1 1 Mycothiol maleylpyruvate isomerase N-terminal domain Fer4 PF00037.27 ABK69968.1 - 1.6e-17 62.5 12.0 1.4e-09 37.3 1.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 ABK69968.1 - 1.2e-15 57.8 15.7 8e-12 45.6 6.6 1.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 ABK69968.1 - 7.5e-12 45.2 16.8 1.2e-08 34.9 8.6 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 ABK69968.1 - 1.1e-11 45.5 2.7 4.3e-06 27.6 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 ABK69968.1 - 1.4e-11 43.7 10.0 3e-06 27.0 1.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 ABK69968.1 - 5.4e-11 42.1 12.2 1.4e-05 24.9 1.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 ABK69968.1 - 4.8e-10 39.4 17.4 1.6e-08 34.6 7.8 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 ABK69968.1 - 3.4e-09 36.7 20.4 4.9e-07 29.8 10.6 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 ABK69968.1 - 6.1e-08 32.6 7.9 0.0013 19.1 1.2 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 ABK69968.1 - 1.1e-07 32.2 26.4 3.1e-05 24.4 9.4 2.0 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_8 PF13183.6 ABK69968.1 - 3.4e-07 30.6 15.9 6.4e-05 23.3 8.8 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 ABK69968.1 - 1.7e-06 28.5 5.9 0.019 15.5 1.6 2.4 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 ABK69968.1 - 2.3e-06 28.2 15.9 0.00096 19.9 3.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.6 ABK69968.1 - 0.00031 20.9 2.4 0.19 12.0 0.4 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_22 PF17179.4 ABK69968.1 - 0.0046 17.8 9.9 0.13 13.1 2.0 2.2 1 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.6 ABK69968.1 - 0.014 16.1 11.5 0.056 14.2 0.2 2.9 2 1 1 3 3 3 0 4Fe-4S single cluster domain c-SKI_SMAD_bind PF08782.10 ABK69968.1 - 0.46 10.7 1.9 7.8 6.8 0.1 2.1 1 1 1 2 2 2 0 c-SKI Smad4 binding domain AFP PF02420.15 ABK69968.1 - 1.1 9.8 9.1 14 6.4 3.4 2.5 2 0 0 2 2 2 0 Insect antifreeze protein repeat PK PF00224.21 ABK69970.1 - 3.4e-110 368.2 0.2 4.4e-110 367.8 0.2 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 ABK69970.1 - 3.8e-22 78.7 0.1 1.7e-21 76.6 0.0 2.1 2 1 0 2 2 2 1 Pyruvate kinase, alpha/beta domain CoA_transf_3 PF02515.17 ABK69972.1 - 1e-96 324.3 0.0 1.7e-96 323.5 0.0 1.3 1 1 0 1 1 1 1 CoA-transferase family III INCENP_ARK-bind PF03941.15 ABK69972.1 - 0.14 12.1 0.1 13 5.8 0.1 2.4 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region MoCF_biosynth PF00994.24 ABK69973.1 - 4e-25 88.2 2.1 4.9e-25 87.9 2.1 1.0 1 0 0 1 1 1 1 Probable molybdopterin binding domain Flg_hook PF02120.16 ABK69973.1 - 0.072 13.0 0.3 1 9.3 0.1 2.7 2 2 2 4 4 4 0 Flagellar hook-length control protein FliK p450 PF00067.22 ABK69974.1 - 4.7e-22 78.4 0.0 3.4e-14 52.4 0.0 2.9 2 1 0 2 2 2 2 Cytochrome P450 FCD PF07729.12 ABK69975.1 - 1.4e-22 80.4 7.9 2.6e-22 79.6 7.9 1.4 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 ABK69975.1 - 1.3e-20 72.8 0.3 2.6e-20 71.8 0.3 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 ABK69975.1 - 0.00039 20.4 0.3 0.00039 20.4 0.3 2.7 3 1 1 4 4 4 1 Helix-turn-helix domain Fe_dep_repress PF01325.19 ABK69975.1 - 0.00046 20.3 0.0 0.00076 19.6 0.0 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain MarR_2 PF12802.7 ABK69975.1 - 0.00076 19.3 0.8 0.0021 17.9 0.1 2.1 2 0 0 2 2 2 1 MarR family TrmB PF01978.19 ABK69975.1 - 0.0024 17.7 0.0 0.0045 16.8 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 ABK69975.1 - 0.005 16.8 0.2 0.023 14.7 0.0 2.0 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain Rnk_N PF14760.6 ABK69975.1 - 0.014 15.9 0.1 0.014 15.9 0.1 2.7 4 0 0 4 4 3 0 Rnk N-terminus HTH_IclR PF09339.10 ABK69975.1 - 0.018 14.8 1.1 0.063 13.1 0.2 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_27 PF13463.6 ABK69975.1 - 0.021 15.3 0.1 0.09 13.3 0.0 2.0 2 0 0 2 2 2 0 Winged helix DNA-binding domain Rrf2 PF02082.20 ABK69975.1 - 0.021 15.2 0.0 0.041 14.2 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator DUF3253 PF11625.8 ABK69975.1 - 0.052 13.8 0.6 8.9 6.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3253) Acetyltransf_6 PF13480.7 ABK69975.1 - 0.055 13.6 0.5 0.055 13.6 0.5 3.1 2 1 1 3 3 3 0 Acetyltransferase (GNAT) domain TFIIE_alpha PF02002.17 ABK69975.1 - 0.062 13.2 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 TFIIE alpha subunit MarR PF01047.22 ABK69975.1 - 0.085 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 MarR family LexA_DNA_bind PF01726.16 ABK69975.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.7 1 1 0 1 1 1 0 LexA DNA binding domain PaaX PF07848.12 ABK69975.1 - 0.13 12.5 0.2 0.27 11.5 0.2 1.5 1 0 0 1 1 1 0 PaaX-like protein HTH_11 PF08279.12 ABK69975.1 - 0.16 11.9 0.0 0.43 10.6 0.0 1.7 1 0 0 1 1 1 0 HTH domain TMEM252 PF15664.5 ABK69975.1 - 0.2 11.4 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 252 family DUF2939 PF11159.8 ABK69975.1 - 0.41 11.1 3.1 0.71 10.3 0.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2939) Abhydrolase_8 PF06259.12 ABK69977.1 - 2.7e-40 137.9 4.7 5e-40 137.0 0.7 2.8 3 0 0 3 3 3 1 Alpha/beta hydrolase Apolipoprotein PF01442.18 ABK69977.1 - 3.7 7.4 9.6 0.25 11.2 0.3 3.0 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain Transcrip_reg PF01709.20 ABK69978.1 - 1.4e-89 299.6 0.0 1.6e-89 299.5 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator Pro_dh PF01619.18 ABK69979.1 - 1.1e-30 107.2 0.0 1.5e-30 106.8 0.0 1.2 1 0 0 1 1 1 1 Proline dehydrogenase PRiA4_ORF3 PF07929.11 ABK69980.1 - 2.1e-51 174.1 0.0 2.5e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein AAA PF00004.29 ABK69981.1 - 3.9e-19 69.4 0.0 7.2e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 ABK69981.1 - 1.2e-14 54.3 4.7 2.3e-14 53.3 1.1 3.0 3 0 0 3 3 3 1 AAA lid domain RuvB_N PF05496.12 ABK69981.1 - 1.2e-05 25.1 0.1 3.1e-05 23.8 0.1 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 ABK69981.1 - 1.7e-05 24.3 0.2 0.001 18.5 0.1 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI TPR_14 PF13428.6 ABK69981.1 - 7.7e-05 23.2 10.5 0.02 15.7 0.2 4.4 4 0 0 4 4 3 1 Tetratricopeptide repeat AAA_16 PF13191.6 ABK69981.1 - 0.0004 20.8 1.0 0.00079 19.8 0.1 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 ABK69981.1 - 0.00079 19.4 0.0 0.002 18.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 ABK69981.1 - 0.0018 18.9 0.0 0.0045 17.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ABK69981.1 - 0.0058 16.9 0.2 0.15 12.4 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 ABK69981.1 - 0.0073 16.0 0.3 0.021 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ABK69981.1 - 0.0078 16.4 0.0 0.031 14.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 ABK69981.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 ABK69981.1 - 0.012 15.9 0.0 0.034 14.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain Fis1_TPR_C PF14853.6 ABK69981.1 - 0.014 15.5 0.1 8.4 6.6 0.0 3.0 3 0 0 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat Sigma54_activat PF00158.26 ABK69981.1 - 0.031 14.0 0.1 0.45 10.2 0.1 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.6 ABK69981.1 - 0.035 14.4 0.7 0.083 13.2 0.1 1.9 2 0 0 2 2 1 0 AAA domain PhoH PF02562.16 ABK69981.1 - 0.058 12.8 0.1 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.6 ABK69981.1 - 0.092 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 ABK69981.1 - 0.13 12.4 0.0 0.37 10.9 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_2 PF07724.14 ABK69981.1 - 0.13 12.3 0.0 0.47 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Rad17 PF03215.15 ABK69981.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain Gp_dh_C PF02800.20 ABK69982.1 - 1.2e-68 229.6 0.0 1.8e-68 229.1 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 ABK69982.1 - 1.5e-33 115.1 0.1 2.7e-33 114.3 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 ABK69982.1 - 0.0043 17.7 0.3 0.031 14.9 0.3 2.2 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 ABK69982.1 - 0.095 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain zf-CGNR PF11706.8 ABK69983.1 - 6.5e-18 64.3 2.5 1e-17 63.6 2.5 1.3 1 0 0 1 1 1 1 CGNR zinc finger ABATE PF07336.11 ABK69983.1 - 1.2e-16 61.6 9.2 1.5e-16 61.2 9.2 1.1 1 0 0 1 1 1 1 Putative stress-induced transcription regulator LAL_C2 PF18603.1 ABK69983.1 - 0.044 13.9 0.1 0.12 12.6 0.1 1.7 1 0 0 1 1 1 0 L-amino acid ligase C-terminal domain 2 Acyl_transf_3 PF01757.22 ABK69984.1 - 4e-25 88.6 28.8 6.3e-25 87.9 28.8 1.3 1 0 0 1 1 1 1 Acyltransferase family Lipase_GDSL PF00657.22 ABK69984.1 - 0.0078 16.2 0.0 0.016 15.2 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DHO_dh PF01180.21 ABK69985.1 - 5.2e-94 314.8 0.0 6e-94 314.6 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase TetR_C_7 PF14246.6 ABK69985.1 - 0.12 12.5 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal domain Aminotran_1_2 PF00155.21 ABK69986.1 - 2.7e-30 105.8 0.0 3.3e-30 105.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 ABK69986.1 - 1.3e-16 60.4 0.1 1.1e-09 37.7 0.0 2.1 2 0 0 2 2 2 2 Alanine-glyoxylate amino-transferase DrsE PF02635.15 ABK69987.1 - 0.014 15.8 0.0 0.018 15.4 0.0 1.1 1 0 0 1 1 1 0 DsrE/DsrF-like family ADH_zinc_N PF00107.26 ABK69988.1 - 1.1e-22 80.4 1.6 1.7e-22 79.8 1.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ABK69988.1 - 9.8e-17 62.2 0.5 1.8e-16 61.4 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ABK69988.1 - 4.3e-09 36.2 0.0 9.3e-09 35.1 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.21 ABK69988.1 - 0.026 14.2 0.8 0.066 12.9 0.5 1.7 1 1 1 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Wzz PF02706.15 ABK69989.1 - 0.11 12.9 0.0 0.11 12.9 0.0 2.0 3 0 0 3 3 3 0 Chain length determinant protein Lactamase_B PF00753.27 ABK69990.1 - 5.8e-11 42.8 3.6 9.2e-11 42.1 3.6 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ABK69990.1 - 5.7e-06 26.0 1.9 1e-05 25.2 0.4 2.1 2 1 1 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ABK69990.1 - 0.056 13.3 0.4 0.17 11.7 0.4 1.8 1 1 1 2 2 2 0 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 ABK69990.1 - 0.23 10.9 0.0 0.36 10.2 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain IMS PF00817.20 ABK69992.1 - 1.7e-39 135.2 0.0 7.7e-39 133.1 0.0 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 ABK69992.1 - 4.6e-10 40.2 0.2 9.5e-10 39.2 0.2 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DNA_pol_lambd_f PF10391.9 ABK69992.1 - 7.4e-05 22.5 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.6 ABK69992.1 - 0.00011 22.7 0.0 0.00029 21.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain IMS_HHH PF11798.8 ABK69992.1 - 0.00066 19.9 0.1 0.0024 18.1 0.0 2.1 3 0 0 3 3 3 1 IMS family HHH motif Cdd1 PF11731.8 ABK69992.1 - 0.0042 17.3 0.0 0.0089 16.2 0.0 1.5 1 0 0 1 1 1 1 Pathogenicity locus BPD_transp_1 PF00528.22 ABK69993.1 - 3.6e-28 98.6 16.6 3.6e-28 98.6 16.6 2.2 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 ABK69993.1 - 2.8e-05 24.0 0.4 2.8e-05 24.0 0.4 3.9 4 0 0 4 4 4 1 N-terminal TM domain of oligopeptide transport permease C DNA_topoisoIV PF00521.20 ABK69994.1 - 1.9e-147 491.6 0.0 2.5e-147 491.2 0.0 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 ABK69994.1 - 5.7e-76 249.8 10.4 4e-13 48.6 0.0 6.4 6 0 0 6 6 6 6 DNA gyrase C-terminal domain, beta-propeller SIS PF01380.22 ABK69994.1 - 0.044 13.6 0.0 0.39 10.6 0.0 2.5 3 0 0 3 3 3 0 SIS domain TPD52 PF04201.15 ABK69994.1 - 0.082 12.5 0.3 0.17 11.5 0.3 1.4 1 0 0 1 1 1 0 Tumour protein D52 family Nnf1 PF03980.14 ABK69994.1 - 0.19 12.1 1.9 0.49 10.8 1.5 1.9 1 1 0 1 1 1 0 Nnf1 NHase_alpha PF02979.16 ABK69995.1 - 9.1e-78 259.8 0.0 1e-77 259.6 0.0 1.0 1 0 0 1 1 1 1 Nitrile hydratase, alpha chain Frankia_peptide PF14407.6 ABK69995.1 - 0.027 14.5 0.0 1.4 9.0 0.0 2.7 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. 4HBT PF03061.22 ABK69996.1 - 1e-11 45.0 0.7 1.3e-11 44.7 0.7 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 ABK69996.1 - 3.6e-07 30.4 0.1 4.6e-07 30.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.6 ABK69996.1 - 0.00014 22.2 0.3 0.00017 21.9 0.3 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily TetR_N PF00440.23 ABK69997.1 - 1.5e-15 56.7 0.1 3.8e-15 55.4 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_7 PF14246.6 ABK69997.1 - 0.019 15.0 0.5 0.043 13.9 0.2 1.8 1 1 1 2 2 2 0 AefR-like transcriptional repressor, C-terminal domain HAD_2 PF13419.6 ABK69997.1 - 0.047 13.8 0.0 0.089 12.9 0.0 1.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase MR_MLE_C PF13378.6 ABK69998.1 - 2.8e-45 154.6 0.3 4.2e-45 154.0 0.3 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 ABK69998.1 - 4.5e-34 117.1 0.0 8.3e-34 116.3 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain baeRF_family10 PF18854.1 ABK69999.1 - 3.6e-33 114.8 7.4 6.6e-33 113.9 4.3 2.4 2 0 0 2 2 2 1 Bacterial archaeo-eukaryotic release factor family 10 baeRF_family5 PF18846.1 ABK69999.1 - 7.5e-07 29.4 2.9 1.7e-05 25.1 0.5 2.8 2 1 0 2 2 2 1 Bacterial archaeo-eukaryotic release factor family 5 baeRF_family3 PF18845.1 ABK69999.1 - 9.7e-07 29.2 0.4 2.6e-06 27.8 0.4 1.7 1 1 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 3 baeRF_family2 PF18844.1 ABK69999.1 - 0.0056 16.8 2.5 0.0056 16.8 2.5 2.7 3 0 0 3 3 3 1 Bacterial archaeo-eukaryotic release factor family 2 Arabinose_Iso_C PF11762.8 ABK69999.1 - 0.051 13.4 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 L-arabinose isomerase C-terminal domain baeRF_family12 PF18856.1 ABK69999.1 - 0.19 12.3 0.4 0.55 10.8 0.4 1.8 1 1 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 12 MIP PF00230.20 ABK70000.1 - 6.3e-47 160.2 14.9 7.1e-47 160.0 14.9 1.0 1 0 0 1 1 1 1 Major intrinsic protein ECH_1 PF00378.20 ABK70001.1 - 2.9e-57 193.8 0.0 3.3e-57 193.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK70001.1 - 5.1e-29 101.8 0.0 1.7e-26 93.5 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase zf-RING_7 PF02591.15 ABK70001.1 - 0.037 14.2 0.1 0.097 12.9 0.1 1.8 2 0 0 2 2 2 0 C4-type zinc ribbon domain UPF0444 PF15475.6 ABK70001.1 - 0.056 13.7 0.2 0.13 12.6 0.2 1.5 1 0 0 1 1 1 0 Transmembrane protein C12orf23, UPF0444 TPM_phosphatase PF04536.14 ABK70001.1 - 0.092 12.9 0.0 0.27 11.4 0.0 1.7 2 0 0 2 2 2 0 TPM domain Hydrolase_3 PF08282.12 ABK70002.1 - 4.8e-61 206.7 0.0 5.5e-61 206.5 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 ABK70002.1 - 3.6e-13 49.6 0.0 1.5e-06 27.9 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.7 ABK70002.1 - 9.4e-08 32.7 3.1 0.036 14.5 0.1 3.3 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ABK70002.1 - 2e-05 25.0 2.8 0.26 11.6 0.1 3.0 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 ABK70002.1 - 0.041 14.0 0.0 0.18 11.9 0.0 2.2 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase K_oxygenase PF13434.6 ABK70003.1 - 1e-15 57.7 0.0 6.7e-15 55.1 0.0 1.9 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 ABK70003.1 - 1.3e-07 31.2 0.1 3.2e-05 23.3 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ABK70003.1 - 4.8e-07 29.3 0.0 1.8e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ABK70003.1 - 5.5e-07 29.7 7.2 0.00014 21.9 1.1 3.8 2 2 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 ABK70003.1 - 0.0021 18.5 0.5 0.0037 17.7 0.0 1.7 2 0 0 2 2 2 1 Putative NAD(P)-binding DAO PF01266.24 ABK70003.1 - 0.011 15.4 3.5 0.13 11.9 1.3 2.8 2 1 1 3 3 3 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 ABK70003.1 - 0.014 15.5 0.1 0.052 13.6 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 ABK70003.1 - 0.019 15.2 0.0 9.4 6.5 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain Lycopene_cycl PF05834.12 ABK70003.1 - 0.037 13.1 2.2 0.22 10.5 0.2 2.4 2 1 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 ABK70003.1 - 0.055 14.0 2.6 9.2 6.9 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 ABK70003.1 - 0.13 12.5 0.6 2.3 8.5 0.0 2.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Trp_halogenase PF04820.14 ABK70003.1 - 0.6 8.9 3.0 12 4.6 0.0 3.1 4 0 0 4 4 4 0 Tryptophan halogenase MFS_1 PF07690.16 ABK70004.1 - 7.6e-45 153.4 53.6 1.7e-32 112.7 28.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK70004.1 - 2e-09 36.8 31.0 1.9e-07 30.3 13.5 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter LacY_symp PF01306.19 ABK70004.1 - 0.0016 17.3 1.5 0.0016 17.3 1.5 2.9 2 1 1 3 3 3 2 LacY proton/sugar symporter MFS_3 PF05977.13 ABK70004.1 - 0.0032 15.9 37.1 0.01 14.2 37.1 1.6 1 1 0 1 1 1 1 Transmembrane secretion effector SBF PF01758.16 ABK70005.1 - 3.5e-66 222.6 2.8 7.7e-66 221.5 2.8 1.6 1 0 0 1 1 1 1 Sodium Bile acid symporter family SBF_like PF13593.6 ABK70005.1 - 4.4e-08 32.8 6.1 5.6e-08 32.5 6.1 1.2 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Kinocilin PF15033.6 ABK70005.1 - 0.13 11.9 1.9 0.16 11.6 0.1 2.0 2 0 0 2 2 2 0 Kinocilin protein DUF2070 PF09843.9 ABK70005.1 - 5.7 5.1 13.1 0.92 7.7 3.6 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) Sigma70_r2 PF04542.14 ABK70006.1 - 3e-14 52.5 0.2 4.8e-14 51.9 0.2 1.3 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 ABK70006.1 - 3.7e-10 39.3 0.0 5.7e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 ABK70006.1 - 1e-06 28.2 0.1 9.5e-06 25.1 0.0 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 ABK70006.1 - 0.0002 21.3 0.0 0.061 13.2 0.0 2.0 2 0 0 2 2 2 2 ECF sigma factor HTH_23 PF13384.6 ABK70006.1 - 0.075 12.9 0.2 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 Homeodomain-like domain Aldedh PF00171.22 ABK70007.1 - 1.3e-156 521.7 0.0 1.5e-156 521.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aminotran_3 PF00202.21 ABK70009.1 - 1.3e-74 251.3 0.0 1.7e-74 250.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III TraF PF13728.6 ABK70009.1 - 0.21 11.4 0.0 0.33 10.7 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein TP_methylase PF00590.20 ABK70010.1 - 1.3e-43 149.4 2.5 1.3e-43 149.4 2.5 1.4 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Ntox10 PF15520.6 ABK70010.1 - 0.014 15.2 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Novel toxin 10 Amidohydro_1 PF01979.20 ABK70011.1 - 5.2e-25 88.5 0.0 9e-25 87.7 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ABK70011.1 - 1.7e-17 64.0 1.6 3.7e-08 33.3 0.0 2.9 2 1 0 3 3 3 2 Amidohydrolase family AP_endonuc_2 PF01261.24 ABK70011.1 - 0.031 13.7 0.0 0.066 12.6 0.0 1.6 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel DHOase PF12890.7 ABK70011.1 - 0.044 13.7 0.0 0.083 12.8 0.0 1.5 1 1 0 1 1 1 0 Dihydro-orotase-like adh_short_C2 PF13561.6 ABK70012.1 - 6.8e-46 156.7 1.6 9.3e-46 156.3 1.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK70012.1 - 2e-37 128.6 0.1 2.6e-37 128.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK70012.1 - 1.9e-08 34.4 0.5 3.2e-08 33.7 0.5 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK70012.1 - 2.4e-06 27.2 0.1 6.6e-06 25.8 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ABK70012.1 - 5.4e-06 26.4 2.1 7.8e-06 25.9 2.1 1.6 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 ABK70012.1 - 0.00022 20.7 0.0 0.00033 20.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 ABK70012.1 - 0.022 14.3 0.2 0.035 13.7 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family Glyco_transf_4 PF13439.6 ABK70012.1 - 0.092 12.7 0.9 0.12 12.3 0.4 1.5 2 0 0 2 2 2 0 Glycosyltransferase Family 4 NAD_binding_7 PF13241.6 ABK70012.1 - 0.1 13.1 0.0 0.1 13.1 0.0 2.0 3 0 0 3 3 3 0 Putative NAD(P)-binding GARS_C PF02843.16 ABK70012.1 - 0.97 9.8 4.2 1.4 9.2 0.2 2.9 2 1 1 3 3 3 0 Phosphoribosylglycinamide synthetase, C domain ADH_N PF08240.12 ABK70013.1 - 4.9e-19 68.2 0.1 9.4e-19 67.3 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ABK70013.1 - 2e-14 53.7 0.1 5.6e-14 52.2 0.1 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ABK70013.1 - 0.0014 18.2 0.1 0.0027 17.2 0.1 1.6 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 ABK70013.1 - 0.0054 17.8 0.0 0.017 16.2 0.0 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 ABK70013.1 - 0.03 14.6 0.4 0.05 13.9 0.4 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 ABK70013.1 - 0.031 14.5 0.2 0.055 13.7 0.2 1.4 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 ABK70013.1 - 0.089 12.4 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 ABK70013.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ABC_tran PF00005.27 ABK70014.1 - 2.6e-51 173.7 0.0 1.3e-27 96.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ABK70014.1 - 2.1e-18 67.2 4.5 0.00041 20.3 0.1 4.3 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 ABK70014.1 - 2.1e-15 56.5 10.3 2.5e-14 53.1 8.1 2.3 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 ABK70014.1 - 4.8e-10 39.3 1.5 0.24 10.8 0.1 4.3 3 1 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ABK70014.1 - 3.4e-05 24.1 0.0 0.16 12.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 ABK70014.1 - 4.9e-05 23.0 0.5 0.12 12.1 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ABK70014.1 - 0.00012 22.2 0.2 0.21 11.7 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ABK70014.1 - 0.00049 20.0 0.2 0.19 11.6 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 ABK70014.1 - 0.00053 20.4 2.5 0.68 10.3 0.0 3.0 3 1 0 3 3 3 2 AAA ATPase domain AAA_24 PF13479.6 ABK70014.1 - 0.0011 18.7 0.2 0.9 9.2 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 ABK70014.1 - 0.0012 19.4 3.0 0.016 15.7 1.4 3.4 4 0 0 4 4 3 2 AAA domain AAA_27 PF13514.6 ABK70014.1 - 0.0014 18.3 0.0 0.87 9.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 ABK70014.1 - 0.0017 18.5 0.2 0.7 10.1 0.1 2.9 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 ABK70014.1 - 0.002 17.9 1.2 0.82 9.3 0.0 2.9 3 0 0 3 3 2 1 AAA ATPase domain AAA_30 PF13604.6 ABK70014.1 - 0.003 17.3 0.1 2.7 7.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 ABK70014.1 - 0.0042 17.2 0.5 0.48 10.4 0.0 2.7 3 0 0 3 3 3 1 Dynamin family AAA PF00004.29 ABK70014.1 - 0.006 17.0 0.3 0.55 10.7 0.1 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 ABK70014.1 - 0.0063 16.7 0.5 16 5.8 0.1 3.9 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATPase_2 PF01637.18 ABK70014.1 - 0.01 15.8 1.3 0.43 10.4 0.0 3.0 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea DLIC PF05783.11 ABK70014.1 - 0.012 14.4 0.1 0.34 9.7 0.1 2.2 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_33 PF13671.6 ABK70014.1 - 0.018 15.2 1.7 2 8.6 0.2 3.0 3 1 0 3 3 2 0 AAA domain AAA_14 PF13173.6 ABK70014.1 - 0.035 14.1 0.1 0.69 9.9 0.1 3.0 4 0 0 4 4 3 0 AAA domain AAA_28 PF13521.6 ABK70014.1 - 0.049 13.9 0.2 8.3 6.6 0.0 3.2 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.22 ABK70014.1 - 0.053 12.7 3.9 0.087 12.0 0.1 2.9 3 1 0 3 3 3 0 NB-ARC domain cobW PF02492.19 ABK70014.1 - 0.055 13.1 0.5 3 7.4 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 ABK70014.1 - 0.076 12.9 0.5 1.5 8.7 0.1 2.4 2 0 0 2 2 2 0 NACHT domain MeaB PF03308.16 ABK70014.1 - 0.11 11.5 0.1 3.6 6.5 0.1 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_13 PF13166.6 ABK70014.1 - 0.12 11.0 0.3 29 3.1 0.0 3.4 4 0 0 4 4 4 0 AAA domain PRK PF00485.18 ABK70014.1 - 0.14 11.8 0.2 13 5.5 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 ABK70014.1 - 0.18 12.2 0.1 12 6.3 0.0 2.4 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.17 ABK70014.1 - 0.22 11.3 0.2 6.8 6.4 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 ABK70014.1 - 0.31 10.9 1.4 2.4 8.1 0.6 2.7 4 0 0 4 4 3 0 NTPase AAA_18 PF13238.6 ABK70014.1 - 0.37 11.3 9.1 2.7 8.5 0.3 3.8 4 3 0 4 4 3 0 AAA domain AMP-binding PF00501.28 ABK70016.1 - 3.4e-74 250.0 0.1 4.1e-74 249.7 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C_2 PF14535.6 ABK70016.1 - 0.12 12.7 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain RDD PF06271.12 ABK70017.1 - 9.6e-28 97.1 3.3 1.1e-27 96.9 3.3 1.1 1 0 0 1 1 1 1 RDD family DUF751 PF05421.11 ABK70017.1 - 0.054 14.2 5.5 0.054 14.2 5.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF751) DUF5455 PF17537.2 ABK70017.1 - 0.33 11.4 4.3 0.18 12.2 1.7 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5455) MARVEL PF01284.23 ABK70017.1 - 0.59 10.2 7.4 4.7 7.2 5.5 2.1 2 0 0 2 2 2 0 Membrane-associating domain Phage_holin_3_3 PF16083.5 ABK70017.1 - 1.2 9.3 8.6 1.6 8.9 0.8 3.0 2 1 1 3 3 3 0 LydA holin phage, holin superfamily III ATP-synt_C PF00137.21 ABK70018.1 - 1.9e-09 37.7 10.5 2.9e-09 37.1 10.5 1.3 1 0 0 1 1 1 1 ATP synthase subunit C Peptidase_M22 PF00814.25 ABK70019.1 - 1e-26 94.2 1.2 1.4e-26 93.9 1.2 1.1 1 0 0 1 1 1 1 Glycoprotease family GATase PF00117.28 ABK70019.1 - 0.21 11.3 0.0 0.3 10.8 0.0 1.1 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Pkinase PF00069.25 ABK70020.1 - 2.5e-45 154.9 0.0 3.4e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SBP_bac_3 PF00497.20 ABK70020.1 - 1.1e-38 132.9 0.0 1.7e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Pkinase_Tyr PF07714.17 ABK70020.1 - 2.3e-32 112.3 0.0 3.1e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ABK70020.1 - 4e-08 33.5 5.1 9e-06 25.8 0.2 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ABK70020.1 - 5.3e-06 25.5 0.0 8.2e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 ABK70020.1 - 0.00021 20.7 0.0 0.00037 19.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Lig_chan-Glu_bd PF10613.9 ABK70020.1 - 0.0021 18.2 0.0 0.024 14.8 0.0 2.4 2 1 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site RIO1 PF01163.22 ABK70020.1 - 0.0059 16.2 0.1 0.022 14.4 0.0 1.9 3 0 0 3 3 3 1 RIO1 family Haspin_kinase PF12330.8 ABK70020.1 - 0.019 13.9 0.0 0.072 12.0 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain rve PF00665.26 ABK70021.1 - 1.8e-23 83.0 0.1 4.5e-23 81.7 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 ABK70021.1 - 8.9e-14 51.4 2.0 2.3e-13 50.1 1.4 2.0 2 0 0 2 2 2 1 HTH-like domain rve_3 PF13683.6 ABK70021.1 - 5.8e-12 45.2 0.0 1.3e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 ABK70021.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain Putative_PNPOx PF01243.20 ABK70022.1 - 8.3e-15 54.8 0.0 1.2e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 ABK70022.1 - 5.4e-05 22.8 0.0 8.3e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like FA_hydroxylase PF04116.13 ABK70024.1 - 4.3e-25 88.6 4.1 4.3e-25 88.6 4.1 1.8 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily DUF937 PF06078.11 ABK70025.1 - 4.8e-21 75.8 20.6 9.6e-19 68.3 3.0 2.1 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF937) Bacteriocin_IIc PF10439.9 ABK70025.1 - 0.087 13.0 15.5 4.1 7.6 0.1 3.1 2 1 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide DUF4442 PF14539.6 ABK70026.1 - 4.1e-55 185.5 3.1 5.8e-55 185.0 3.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) AA_permease PF00324.21 ABK70027.1 - 3.2e-36 125.0 33.4 4.2e-36 124.6 33.4 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ABK70027.1 - 1.2e-34 119.9 33.3 1.6e-34 119.5 33.3 1.2 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.18 ABK70027.1 - 0.02 13.6 23.6 0.061 12.0 12.1 3.2 2 1 0 2 2 2 0 Transmembrane amino acid transporter protein Bac_luciferase PF00296.20 ABK70028.1 - 5e-79 266.0 10.6 5.9e-79 265.7 10.6 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase HrpE PF06188.12 ABK70028.1 - 0.045 13.6 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E Amidase PF01425.21 ABK70029.1 - 3.5e-97 326.2 0.0 4.6e-97 325.8 0.0 1.2 1 0 0 1 1 1 1 Amidase FCD PF07729.12 ABK70029.1 - 1.6e-19 70.6 5.2 3.5e-19 69.4 5.2 1.6 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 ABK70029.1 - 1.6e-16 59.7 1.3 1.2e-15 56.9 0.3 2.6 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 ABK70029.1 - 0.007 15.9 0.0 0.021 14.3 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding PaaX PF07848.12 ABK70029.1 - 0.03 14.5 0.8 3 8.1 0.1 3.0 3 0 0 3 3 3 0 PaaX-like protein HTH_AsnC-type PF13404.6 ABK70029.1 - 0.071 12.9 0.3 0.35 10.8 0.3 2.3 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Abhydrolase_1 PF00561.20 ABK70030.1 - 2.1e-18 66.9 1.1 1.2e-16 61.2 1.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK70030.1 - 2.4e-17 64.3 18.0 3e-17 64.0 18.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK70030.1 - 4.7e-05 22.8 0.5 8.9e-05 21.9 0.5 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 ABK70030.1 - 0.015 15.1 4.8 0.12 12.2 1.7 2.8 2 1 1 3 3 3 0 Serine hydrolase Rhomboid PF01694.22 ABK70031.1 - 7.3e-35 120.2 18.1 7.3e-35 120.2 18.1 2.4 2 1 1 3 3 3 1 Rhomboid family IBV_3A PF03617.13 ABK70031.1 - 0.049 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 IBV 3A protein Foamy_virus_ENV PF03408.14 ABK70031.1 - 1.6 6.5 2.5 2.1 6.1 2.5 1.1 1 0 0 1 1 1 0 Foamy virus envelope protein AsnC_trans_reg PF01037.21 ABK70032.1 - 4e-17 61.9 0.5 1.8e-16 59.9 0.0 2.0 2 0 0 2 2 2 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 ABK70032.1 - 4.8e-17 61.3 0.1 7.3e-17 60.7 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 ABK70032.1 - 7.2e-17 60.9 2.1 8.2e-17 60.8 1.0 1.7 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain MarR_2 PF12802.7 ABK70032.1 - 0.00045 20.0 0.1 0.0011 18.9 0.1 1.6 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 ABK70032.1 - 0.0045 16.8 0.0 0.0077 16.0 0.0 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_20 PF12840.7 ABK70032.1 - 0.0053 16.8 0.1 0.0092 16.0 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 ABK70032.1 - 0.019 15.0 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain MarR PF01047.22 ABK70032.1 - 0.022 14.7 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_28 PF13518.6 ABK70032.1 - 0.04 14.1 0.0 0.069 13.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain TPR_12 PF13424.6 ABK70033.1 - 2.1e-06 27.9 2.0 0.0015 18.8 0.2 4.3 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 ABK70033.1 - 0.0038 17.1 4.0 2.5 8.3 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 ABK70033.1 - 0.021 14.9 6.6 3.3 8.1 0.1 4.9 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 ABK70033.1 - 0.028 15.0 2.3 0.028 15.0 2.3 7.6 8 1 0 9 9 9 0 Tetratricopeptide repeat TPR_14 PF13428.6 ABK70033.1 - 0.071 14.0 2.1 0.071 14.0 2.1 6.7 5 3 1 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 ABK70033.1 - 0.08 12.8 0.2 19 5.3 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat YfdX PF10938.8 ABK70033.1 - 5.9 6.8 7.9 0.79 9.6 0.5 3.1 3 1 0 4 4 4 0 YfdX protein HTH_38 PF13936.6 ABK70034.1 - 1.4e-19 69.6 3.5 1.6e-18 66.2 2.5 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain rve PF00665.26 ABK70034.1 - 9.8e-08 32.2 0.0 4.1e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain HTH_23 PF13384.6 ABK70034.1 - 1.5e-06 27.8 8.6 3.8e-05 23.3 1.7 4.4 4 0 0 4 4 4 1 Homeodomain-like domain HTH_32 PF13565.6 ABK70034.1 - 0.00024 21.6 13.3 0.00077 20.0 4.8 4.1 2 1 1 3 3 3 1 Homeodomain-like domain rve_3 PF13683.6 ABK70034.1 - 0.0016 18.2 0.0 0.0051 16.6 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain HTH_28 PF13518.6 ABK70034.1 - 0.002 18.2 1.9 0.014 15.5 1.9 2.6 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 ABK70034.1 - 0.0024 17.5 0.3 0.11 12.2 0.1 3.0 3 0 0 3 3 3 1 Sigma-70, region 4 GerE PF00196.19 ABK70034.1 - 0.023 14.2 0.4 0.1 12.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family HTH_20 PF12840.7 ABK70034.1 - 0.071 13.2 0.5 2.5 8.2 0.0 3.4 4 0 0 4 4 4 0 Helix-turn-helix domain PGM_PMM_I PF02878.16 ABK70035.1 - 2.2e-39 134.3 0.1 6.2e-39 132.9 0.1 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 ABK70035.1 - 7e-31 106.8 1.3 1.8e-30 105.5 0.7 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 ABK70035.1 - 5.5e-17 62.3 0.3 1.5e-16 60.9 0.3 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 ABK70035.1 - 4e-15 55.7 2.2 1.6e-14 53.8 2.2 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Atracotoxin PF05353.11 ABK70037.1 - 0.0088 16.1 2.6 7.2 6.8 0.0 3.1 3 0 0 3 3 3 2 Delta Atracotoxin CaiF_GrlA PF07180.11 ABK70037.1 - 0.1 12.6 0.1 21 5.1 0.0 2.2 2 0 0 2 2 2 0 CaiF/GrlA transcriptional regulator Glyoxalase_6 PF18029.1 ABK70038.1 - 9.5e-28 97.1 0.3 1.1e-27 96.9 0.3 1.0 1 0 0 1 1 1 1 Glyoxalase-like domain Abhydrolase_9 PF10081.9 ABK70039.1 - 1.1e-131 438.1 0.2 1.5e-131 437.8 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta-hydrolase family Abhydrolase_9_N PF15420.6 ABK70039.1 - 1.7e-71 240.6 10.0 3.3e-71 239.6 10.0 1.5 1 0 0 1 1 1 1 Alpha/beta-hydrolase family N-terminus Spore_permease PF03845.13 ABK70039.1 - 0.52 9.1 4.7 0.77 8.5 4.7 1.1 1 0 0 1 1 1 0 Spore germination protein NAPRTase_N PF17767.1 ABK70040.1 - 6.8e-26 91.1 0.0 1.2e-25 90.3 0.0 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase PF04095.16 ABK70040.1 - 1.8e-06 27.7 2.5 6.5e-05 22.6 2.5 3.1 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family QRPTase_C PF01729.19 ABK70040.1 - 5.9e-05 22.9 0.2 9.8e-05 22.2 0.2 1.3 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain B3_4 PF03483.17 ABK70041.1 - 7.3e-58 195.1 0.0 1.1e-57 194.5 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain tRNA_synthFbeta PF17759.1 ABK70041.1 - 2.6e-57 193.7 0.0 3.8e-57 193.2 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain FDX-ACB PF03147.14 ABK70041.1 - 2.3e-26 92.0 0.0 4.9e-26 91.0 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA_bind PF01588.20 ABK70041.1 - 4.8e-19 68.3 0.0 8.8e-19 67.4 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain B5 PF03484.15 ABK70041.1 - 8e-15 54.9 0.0 3.4e-14 52.9 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetase B5 domain DUF2000 PF09391.10 ABK70042.1 - 1.2e-41 141.7 0.0 1.3e-41 141.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2000) BPD_transp_1 PF00528.22 ABK70043.1 - 6.3e-26 91.2 15.9 6.3e-26 91.2 15.9 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component adh_short PF00106.25 ABK70044.1 - 2.4e-24 85.9 2.5 3e-23 82.3 2.5 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK70044.1 - 7.1e-12 45.4 0.9 1.7e-11 44.2 0.9 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK70044.1 - 1.2e-06 28.6 0.4 2.5e-06 27.5 0.4 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK70044.1 - 7.1e-06 25.7 0.0 9e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 ABK70044.1 - 0.0036 17.6 0.7 0.006 16.8 0.7 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 ABK70044.1 - 0.0093 15.9 0.6 0.016 15.1 0.3 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Shikimate_DH PF01488.20 ABK70044.1 - 0.029 14.4 0.0 0.048 13.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase YjeF_N PF03853.15 ABK70044.1 - 0.038 13.9 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus RmlD_sub_bind PF04321.17 ABK70044.1 - 0.057 12.5 0.3 0.099 11.7 0.3 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain FAD_binding_3 PF01494.19 ABK70044.1 - 0.057 12.7 0.1 0.088 12.0 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain NmrA PF05368.13 ABK70044.1 - 0.14 11.7 1.4 0.21 11.1 1.4 1.2 1 0 0 1 1 1 0 NmrA-like family FmdA_AmdA PF03069.15 ABK70045.1 - 1.3e-165 550.8 0.0 1.5e-165 550.6 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family SBP_bac_5 PF00496.22 ABK70047.1 - 1e-75 255.1 0.0 1.3e-75 254.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle RNase_PH PF01138.21 ABK70048.1 - 2.2e-24 86.5 0.6 3.6e-24 85.7 0.1 1.6 2 1 1 3 3 3 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 ABK70048.1 - 9.9e-10 38.3 0.0 1.9e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 COXG PF06240.13 ABK70048.1 - 0.06 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit G (CoxG) UvrD-helicase PF00580.21 ABK70050.1 - 2.8e-54 184.8 0.0 8.5e-54 183.2 0.0 1.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 ABK70050.1 - 7.7e-24 84.7 0.0 2.7e-23 82.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain UvrD_C PF13361.6 ABK70050.1 - 8.3e-16 58.3 0.0 1.9e-09 37.4 0.0 2.2 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 ABK70050.1 - 2.2e-06 27.5 8.2 0.00047 19.9 0.3 2.8 3 0 0 3 3 3 2 AAA domain UvrD_C_2 PF13538.6 ABK70050.1 - 9.9e-06 25.3 0.4 0.13 12.1 0.1 2.9 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain PDDEXK_1 PF12705.7 ABK70050.1 - 3.8e-05 23.7 0.0 0.00022 21.2 0.0 2.1 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily PhoH PF02562.16 ABK70050.1 - 0.055 12.9 0.1 2.9 7.3 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Viral_helicase1 PF01443.18 ABK70050.1 - 0.17 11.6 0.1 18 5.0 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase HEAT_2 PF13646.6 ABK70050.1 - 1.5 9.3 14.4 0.059 13.8 2.3 4.0 3 1 1 4 4 4 0 HEAT repeats Putative_PNPOx PF01243.20 ABK70051.1 - 2.6e-10 40.3 0.0 3.9e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 ABK70051.1 - 0.0073 15.9 0.0 0.0085 15.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like F420H2_quin_red PF04075.14 ABK70051.1 - 0.072 13.2 0.0 0.094 12.8 0.0 1.2 1 0 0 1 1 1 0 F420H(2)-dependent quinone reductase MarR_2 PF12802.7 ABK70052.1 - 6.6e-15 54.8 0.1 1.6e-14 53.5 0.1 1.7 1 0 0 1 1 1 1 MarR family MarR PF01047.22 ABK70052.1 - 3.8e-13 49.1 0.2 8.1e-13 48.1 0.0 1.6 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 ABK70052.1 - 1.2e-07 32.1 0.1 2.7e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_24 PF13412.6 ABK70052.1 - 5.6e-06 25.8 0.0 1.1e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 ABK70052.1 - 0.00013 21.7 0.1 0.00039 20.2 0.1 1.8 1 0 0 1 1 1 1 IclR helix-turn-helix domain SMC_ScpB PF04079.16 ABK70052.1 - 0.00095 18.8 0.1 0.0012 18.5 0.1 1.2 1 0 0 1 1 1 1 Segregation and condensation complex subunit ScpB HTH_20 PF12840.7 ABK70052.1 - 0.001 19.1 0.0 0.0029 17.6 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain Penicillinase_R PF03965.16 ABK70052.1 - 0.0027 18.1 0.1 0.0036 17.6 0.1 1.4 1 1 0 1 1 1 1 Penicillinase repressor TrmB PF01978.19 ABK70052.1 - 0.006 16.5 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB GerE PF00196.19 ABK70052.1 - 0.04 13.5 0.0 0.097 12.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_5 PF01022.20 ABK70052.1 - 0.045 13.6 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Fe_dep_repress PF01325.19 ABK70052.1 - 0.079 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain RPA_C PF08784.11 ABK70052.1 - 0.15 12.8 0.0 0.28 11.9 0.0 1.4 1 0 0 1 1 1 0 Replication protein A C terminal Fer2_2 PF01799.20 ABK70053.1 - 5.6e-26 90.4 0.1 5.6e-26 90.4 0.1 1.7 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fer2 PF00111.27 ABK70053.1 - 2.4e-08 33.8 2.9 4.3e-08 33.0 2.0 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 ABK70053.1 - 0.00023 21.1 0.2 0.00035 20.6 0.2 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Nitroreductase PF00881.24 ABK70054.1 - 2.4e-11 44.0 0.1 2.7e-11 43.8 0.1 1.1 1 0 0 1 1 1 1 Nitroreductase family PE-PPE PF08237.11 ABK70056.1 - 8e-09 35.4 1.8 3.4e-07 30.0 0.2 2.9 3 0 0 3 3 3 1 PE-PPE domain Baculo_PEP_C PF04513.12 ABK70056.1 - 0.032 14.3 0.5 13 5.8 0.0 2.6 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 ABK70056.1 - 0.23 11.3 2.6 0.44 10.4 2.3 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF948 PF06103.11 ABK70056.1 - 2.4 8.5 6.1 10 6.5 1.9 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) GAF PF01590.26 ABK70057.1 - 1.6e-08 35.3 0.0 2.8e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 GAF domain DapB_N PF01113.20 ABK70058.1 - 1.8e-06 28.1 0.1 3.1e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 ABK70058.1 - 0.15 12.9 0.2 0.58 11.0 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold HTH_Tnp_1 PF01527.20 ABK70059.1 - 1.3e-09 38.2 0.1 1.9e-09 37.7 0.1 1.4 1 1 0 1 1 1 1 Transposase HTH_23 PF13384.6 ABK70059.1 - 9e-06 25.3 0.1 2e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 ABK70059.1 - 0.007 16.5 0.0 0.013 15.6 0.0 1.6 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_10 PF04967.12 ABK70059.1 - 0.0094 15.7 0.0 0.055 13.3 0.0 2.1 2 0 0 2 2 2 1 HTH DNA binding domain Docking PF08990.11 ABK70059.1 - 0.012 15.2 1.4 0.32 10.6 0.3 2.4 2 0 0 2 2 2 0 Erythronolide synthase docking HTH_Tnp_1_2 PF13022.6 ABK70059.1 - 0.018 15.2 0.0 0.029 14.5 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_29 PF13551.6 ABK70059.1 - 0.032 14.3 0.0 0.062 13.3 0.0 1.5 1 1 0 1 1 1 0 Winged helix-turn helix Rrf2 PF02082.20 ABK70059.1 - 0.036 14.4 0.0 0.28 11.5 0.0 2.0 2 1 0 2 2 2 0 Transcriptional regulator ANT PF03374.14 ABK70059.1 - 0.037 14.4 0.0 0.078 13.3 0.0 1.4 1 1 0 1 1 1 0 Phage antirepressor protein KilAC domain HTH_11 PF08279.12 ABK70059.1 - 0.059 13.3 0.0 0.57 10.2 0.0 2.1 2 0 0 2 2 2 0 HTH domain HTH_AraC PF00165.23 ABK70059.1 - 0.083 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_Tnp_4 PF13613.6 ABK70059.1 - 0.12 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease PgaD PF13994.6 ABK70059.1 - 0.2 11.7 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 PgaD-like protein Acetyltransf_3 PF13302.7 ABK70060.1 - 2.2e-07 31.6 0.1 1e-06 29.4 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ABK70060.1 - 2.2e-05 24.8 0.0 4.6e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ABK70060.1 - 2.8e-05 24.3 0.0 4.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DNA_topoisoIV PF00521.20 ABK70060.1 - 0.00037 19.5 0.0 0.00053 19.0 0.0 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A Acetyltransf_10 PF13673.7 ABK70060.1 - 0.0034 17.3 0.0 0.0072 16.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.6 ABK70060.1 - 0.052 12.9 0.0 0.084 12.3 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 BPD_transp_1 PF00528.22 ABK70061.1 - 2.1e-19 70.0 23.2 2.1e-19 70.0 23.2 1.6 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component PEPcase PF00311.17 ABK70062.1 - 1.7e-267 889.7 0.0 2.1e-267 889.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.6 ABK70062.1 - 0.0024 16.5 0.0 0.0041 15.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase Response_reg PF00072.24 ABK70063.1 - 2.6e-17 63.0 0.0 4.5e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 ABK70063.1 - 2.8e-13 49.2 0.1 5.6e-13 48.2 0.0 1.5 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 ABK70063.1 - 9.8e-06 25.2 0.0 1.7e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 ABK70063.1 - 0.00021 20.7 0.2 0.00052 19.5 0.0 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.6 ABK70063.1 - 0.14 12.0 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Ad_Cy_reg PF16701.5 ABK70064.1 - 1.6e-84 282.3 7.9 2.4e-84 281.7 7.9 1.2 1 0 0 1 1 1 1 Adenylate cyclase regulatory domain Guanylate_cyc PF00211.20 ABK70064.1 - 1.9e-17 63.5 0.0 5.7e-17 61.9 0.0 1.7 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain FAM70 PF14967.6 ABK70065.1 - 0.12 11.8 1.0 0.13 11.7 1.0 1.0 1 0 0 1 1 1 0 FAM70 protein DUF4245 PF14030.6 ABK70065.1 - 0.21 11.6 2.3 0.22 11.5 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4245) TRIQK PF15168.6 ABK70065.1 - 1.2 9.0 3.9 1.3 9.0 3.9 1.1 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family TAT_signal PF10518.9 ABK70066.1 - 0.1 12.5 1.0 0.1 12.5 1.0 3.7 5 0 0 5 5 5 0 TAT (twin-arginine translocation) pathway signal sequence MDMPI_N PF11716.8 ABK70068.1 - 6.9e-23 81.9 18.6 6.9e-23 81.9 18.6 1.4 2 0 0 2 2 2 1 Mycothiol maleylpyruvate isomerase N-terminal domain DinB_2 PF12867.7 ABK70068.1 - 0.00012 22.6 1.4 0.00021 21.8 1.4 1.4 1 0 0 1 1 1 1 DinB superfamily DUF664 PF04978.12 ABK70068.1 - 0.055 13.9 2.3 1.4 9.3 2.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF664) Abhydrolase_6 PF12697.7 ABK70069.1 - 5.4e-07 30.4 13.7 7.4e-07 30.0 13.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK70069.1 - 0.00014 21.2 0.4 0.00039 19.8 0.4 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 ABK70069.1 - 0.0017 18.5 0.1 0.0024 18.0 0.1 1.3 1 1 0 1 1 1 1 Thioesterase domain Patatin PF01734.22 ABK70069.1 - 0.049 13.8 0.2 0.065 13.4 0.2 1.3 1 0 0 1 1 1 0 Patatin-like phospholipase Cupin_2 PF07883.11 ABK70070.1 - 9.7e-06 25.2 0.6 0.21 11.3 0.0 3.7 4 0 0 4 4 4 2 Cupin domain Cupin_6 PF12852.7 ABK70070.1 - 0.00025 20.8 1.5 0.24 11.1 0.1 2.5 2 0 0 2 2 2 2 Cupin Cupin_3 PF05899.12 ABK70070.1 - 0.071 12.8 0.4 3.6 7.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF861) PMI_typeI PF01238.21 ABK70070.1 - 0.09 12.0 0.0 0.37 9.9 0.0 2.0 3 0 0 3 3 3 0 Phosphomannose isomerase type I MMM1 PF10296.9 ABK70071.1 - 0.052 12.6 0.0 0.066 12.2 0.0 1.1 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 Abhydrolase_6 PF12697.7 ABK70072.1 - 2.4e-11 44.7 15.0 2.9e-11 44.4 15.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ABK70072.1 - 1.2e-07 31.6 0.1 2.8e-07 30.5 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Pantoate_ligase PF02569.15 ABK70073.1 - 2.3e-97 325.4 0.0 2.6e-97 325.2 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase PALP PF00291.25 ABK70074.1 - 3.5e-59 200.6 0.1 4.9e-59 200.1 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NAD_binding_1 PF00175.21 ABK70076.1 - 2.7e-18 66.6 0.0 2.1e-17 63.7 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 ABK70076.1 - 2e-16 60.1 0.0 4e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Fer2 PF00111.27 ABK70076.1 - 1.3e-12 47.5 0.3 2.8e-12 46.4 0.3 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_6 PF08030.12 ABK70076.1 - 0.00028 21.0 0.0 0.01 16.0 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Fer2_4 PF13510.6 ABK70076.1 - 0.03 14.4 0.0 0.078 13.0 0.0 1.7 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Nup54 PF13874.6 ABK70077.1 - 0.16 12.0 0.3 0.21 11.7 0.3 1.1 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 LPAM_1 PF08139.12 ABK70077.1 - 3.3 8.4 5.8 7.1 7.3 5.8 1.5 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site CPSase_L_D2 PF02786.17 ABK70078.1 - 1.5e-58 197.8 0.0 2.4e-58 197.1 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ABK70078.1 - 3.6e-38 130.5 0.1 6.7e-38 129.6 0.1 1.4 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ABK70078.1 - 9.6e-33 112.5 0.0 3.4e-32 110.7 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 ABK70078.1 - 5.1e-17 61.5 0.2 1.5e-16 60.0 0.2 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 ABK70078.1 - 2.1e-08 33.9 0.3 0.00042 20.1 0.1 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 ABK70078.1 - 2.4e-08 33.8 0.0 4.8e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD_3 PF13437.6 ABK70078.1 - 2.6e-06 28.1 1.0 0.0022 18.7 0.1 3.2 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 ABK70078.1 - 9.4e-05 21.7 0.2 0.019 14.2 0.0 2.3 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_3 PF02655.14 ABK70078.1 - 0.00063 19.8 0.0 0.001 19.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Peptidase_M23 PF01551.22 ABK70078.1 - 0.025 14.8 0.9 0.15 12.3 0.0 2.6 3 0 0 3 3 3 0 Peptidase family M23 ATP-grasp PF02222.22 ABK70078.1 - 0.029 13.9 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain GCV_H PF01597.19 ABK70078.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein ECH_1 PF00378.20 ABK70079.1 - 6.2e-52 176.4 0.2 1.8e-51 174.9 0.2 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK70079.1 - 4.2e-25 88.9 1.0 5.4e-20 72.2 0.3 2.9 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase UPF0444 PF15475.6 ABK70079.1 - 0.064 13.5 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Transmembrane protein C12orf23, UPF0444 Acetyltransf_1 PF00583.25 ABK70080.1 - 5.6e-06 26.6 0.0 1.2e-05 25.5 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_6 PF13480.7 ABK70080.1 - 1.7e-05 25.0 0.7 3.7e-05 23.9 0.7 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ABK70080.1 - 0.00012 22.1 0.1 0.0002 21.4 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ABK70080.1 - 0.00016 22.1 0.0 0.00031 21.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ABK70080.1 - 0.00039 20.3 0.0 0.00067 19.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FANCD2OS PF15124.6 ABK70080.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.6 2 0 0 2 2 2 0 FANCD2 opposite strand protein Peptidase_S8 PF00082.22 ABK70081.1 - 8e-31 107.4 4.6 5.3e-30 104.7 4.6 1.9 1 1 0 1 1 1 1 Subtilase family Peripla_BP_3 PF13377.6 ABK70082.1 - 2.5e-33 115.8 0.5 6e-33 114.5 0.5 1.7 1 0 0 1 1 1 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 ABK70082.1 - 3e-24 85.9 0.0 4.2e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 ABK70082.1 - 4.3e-16 58.4 1.0 7.5e-16 57.6 1.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 ABK70082.1 - 2.6e-09 37.0 0.0 1.4e-08 34.7 0.0 1.9 1 1 1 2 2 2 1 Periplasmic binding protein domain Polyketide_cyc2 PF10604.9 ABK70083.1 - 5.6e-16 59.1 2.7 6.8e-16 58.8 2.7 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 ABK70083.1 - 0.0014 18.9 0.8 0.0021 18.3 0.8 1.4 1 1 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Amidohydro_1 PF01979.20 ABK70084.1 - 8.1e-57 193.1 0.0 1e-56 192.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ABK70084.1 - 8.4e-17 61.8 3.7 1.3e-12 47.9 0.7 2.2 1 1 1 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 ABK70084.1 - 0.033 13.5 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Adenosine/AMP deaminase LPAM_1 PF08139.12 ABK70084.1 - 5 7.8 5.2 15 6.3 5.2 1.8 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Amino_oxidase PF01593.24 ABK70085.1 - 9.9e-33 114.1 0.6 1.3e-32 113.8 0.6 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ABK70085.1 - 3.3e-15 56.0 0.3 7.8e-15 54.9 0.1 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ABK70085.1 - 3.7e-10 40.0 0.2 0.0005 20.1 0.1 3.1 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.24 ABK70085.1 - 9.9e-06 25.4 3.0 1.8e-05 24.5 0.5 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ABK70085.1 - 0.0023 17.2 0.1 0.04 13.1 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rossmann-like PF10727.9 ABK70085.1 - 0.0062 16.4 0.3 0.41 10.5 0.1 2.6 2 0 0 2 2 2 1 Rossmann-like domain Trp_halogenase PF04820.14 ABK70085.1 - 0.061 12.2 0.0 0.091 11.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.7 ABK70085.1 - 0.089 12.1 0.9 0.14 11.5 0.9 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 ABK70085.1 - 0.15 12.6 0.0 0.36 11.4 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ABK70085.1 - 0.25 10.0 0.1 1.6 7.4 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein MCRA PF06100.11 ABK70085.1 - 0.33 9.7 0.0 0.44 9.3 0.0 1.1 1 0 0 1 1 1 0 MCRA family FAD_binding_2 PF00890.24 ABK70085.1 - 0.51 9.4 6.4 0.72 8.9 1.2 2.9 2 2 1 3 3 3 0 FAD binding domain GDP_Man_Dehyd PF16363.5 ABK70086.1 - 4.2e-77 259.8 0.0 4.9e-77 259.6 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ABK70086.1 - 7.5e-63 212.2 0.1 9.1e-63 211.9 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ABK70086.1 - 8.2e-19 67.7 0.0 1e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ABK70086.1 - 7.1e-18 64.7 0.0 9.9e-18 64.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 ABK70086.1 - 6.3e-15 55.0 0.4 1.6e-13 50.4 0.4 2.2 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 ABK70086.1 - 4.4e-10 39.2 0.0 8e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 ABK70086.1 - 5e-07 29.8 0.1 8.4e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 ABK70086.1 - 0.015 14.8 0.5 3.7 7.0 0.1 2.2 2 0 0 2 2 2 0 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 ABK70086.1 - 0.024 14.9 0.2 0.054 13.8 0.2 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 ABK70086.1 - 0.2 11.2 0.6 0.42 10.1 0.4 1.6 2 0 0 2 2 2 0 NmrA-like family Usp PF00582.26 ABK70087.1 - 2.2e-23 83.3 5.2 2.7e-14 53.9 1.1 2.1 2 0 0 2 2 2 2 Universal stress protein family DapB_N PF01113.20 ABK70088.1 - 9.4e-06 25.8 0.0 2.4e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 ABK70088.1 - 0.13 12.8 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain rve PF00665.26 ABK70089.1 - 3.1e-21 75.8 0.0 5.4e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 ABK70089.1 - 7.4e-17 60.9 0.0 1.6e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 ABK70089.1 - 2e-12 47.1 1.1 8.4e-12 45.0 1.6 1.8 2 0 0 2 2 2 1 HTH-like domain rve_2 PF13333.6 ABK70089.1 - 3.1e-07 30.4 0.3 1e-06 28.8 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain MarR PF01047.22 ABK70090.1 - 2.5e-13 49.7 0.0 4.4e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 ABK70090.1 - 1.4e-08 34.2 0.1 2.8e-08 33.2 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 ABK70090.1 - 6.5e-08 32.4 2.8 1.8e-07 30.9 0.2 2.3 2 0 0 2 2 2 1 MarR family HTH_AsnC-type PF13404.6 ABK70090.1 - 3.6e-05 23.5 0.3 0.00015 21.5 0.3 2.1 1 1 0 1 1 1 1 AsnC-type helix-turn-helix domain TrmB PF01978.19 ABK70090.1 - 5.1e-05 23.1 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 ABK70090.1 - 8.8e-05 22.4 1.2 0.00068 19.6 0.1 2.2 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain FeoC PF09012.10 ABK70090.1 - 0.0011 19.0 0.2 0.0041 17.2 0.0 1.9 2 0 0 2 2 2 1 FeoC like transcriptional regulator HTH_11 PF08279.12 ABK70090.1 - 0.002 18.0 0.0 0.004 17.1 0.0 1.5 1 0 0 1 1 1 1 HTH domain LexA_DNA_bind PF01726.16 ABK70090.1 - 0.0036 17.0 0.8 0.019 14.7 0.1 2.3 2 1 0 2 2 2 1 LexA DNA binding domain Raf1_N PF18578.1 ABK70090.1 - 0.0064 16.9 0.2 0.0064 16.9 0.2 1.9 1 1 1 2 2 2 1 Rubisco accumulation factor 1 alpha helical domain HTH_27 PF13463.6 ABK70090.1 - 0.0089 16.5 0.0 0.016 15.7 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain Rrf2 PF02082.20 ABK70090.1 - 0.014 15.7 0.0 0.035 14.4 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator HTH_38 PF13936.6 ABK70090.1 - 0.016 15.0 0.2 0.99 9.2 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_IclR PF09339.10 ABK70090.1 - 0.038 13.8 1.3 0.077 12.8 0.0 2.1 2 0 0 2 2 2 0 IclR helix-turn-helix domain YdaS_antitoxin PF15943.5 ABK70090.1 - 0.09 12.7 0.8 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 ABK70090.1 - 0.27 11.1 2.5 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain E1-E2_ATPase PF00122.20 ABK70091.1 - 4.4e-41 140.4 5.1 1.1e-40 139.1 5.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 ABK70091.1 - 4.7e-41 141.4 1.8 6e-41 141.1 0.8 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ABK70091.1 - 7e-06 26.6 0.2 2.5e-05 24.7 0.2 2.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ABK70091.1 - 0.00085 19.1 0.1 0.0028 17.5 0.2 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase FecCD PF01032.18 ABK70092.1 - 4.7e-88 295.2 27.9 5.9e-88 294.9 27.9 1.0 1 0 0 1 1 1 1 FecCD transport family CN_hydrolase PF00795.22 ABK70093.1 - 1.3e-44 152.5 0.0 1.5e-44 152.3 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DAO PF01266.24 ABK70094.1 - 7.5e-61 206.6 5.9 9.2e-61 206.4 5.9 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ABK70094.1 - 1.5e-07 31.5 0.1 3.8e-07 30.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 ABK70094.1 - 1.6e-05 24.4 1.0 2.7e-05 23.6 1.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 ABK70094.1 - 2.1e-05 24.6 0.9 0.19 11.7 0.2 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 ABK70094.1 - 6.9e-05 22.2 2.3 0.0026 17.0 0.7 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ABK70094.1 - 0.00033 19.9 1.4 0.00033 19.9 1.4 2.1 2 1 1 3 3 3 1 FAD binding domain Amino_oxidase PF01593.24 ABK70094.1 - 0.00038 19.9 0.6 0.38 10.0 0.1 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 ABK70094.1 - 0.00047 20.7 1.6 0.0011 19.5 1.6 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 ABK70094.1 - 0.0015 18.2 0.9 0.0034 17.0 0.9 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 ABK70094.1 - 0.0077 15.8 1.0 0.013 15.1 1.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.17 ABK70094.1 - 0.014 14.7 1.1 0.03 13.6 1.1 1.5 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 ABK70094.1 - 0.016 14.3 2.2 4.4 6.3 2.6 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 ABK70094.1 - 0.018 14.3 0.6 0.3 10.3 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 ABK70094.1 - 0.022 14.3 0.1 0.042 13.3 0.1 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus HI0933_like PF03486.14 ABK70094.1 - 0.034 12.9 1.3 1.5 7.4 0.8 2.5 2 1 1 3 3 3 0 HI0933-like protein AlaDh_PNT_C PF01262.21 ABK70094.1 - 0.074 12.3 2.9 0.18 11.1 2.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 ABK70094.1 - 0.092 12.6 1.5 0.18 11.7 1.5 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DNA_pol_A_exo1 PF01612.20 ABK70095.1 - 1.1e-31 109.8 0.0 1.7e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease DNA_pol_A_exoN PF18305.1 ABK70095.1 - 1.3e-26 92.7 5.2 1.3e-26 92.7 5.2 2.5 3 0 0 3 3 3 1 3' to 5' exonuclease C-terminal domain HRDC PF00570.23 ABK70095.1 - 2.2e-14 53.2 0.1 2.2e-14 53.2 0.1 1.9 2 0 0 2 2 2 1 HRDC domain Response_reg PF00072.24 ABK70096.1 - 4.3e-31 107.4 0.0 6.1e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 ABK70096.1 - 1.4e-22 79.5 0.1 2.8e-22 78.6 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal GerE PF00196.19 ABK70096.1 - 0.00069 19.1 0.3 0.004 16.7 0.4 2.2 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family Abhydrolase_1 PF00561.20 ABK70097.1 - 3.9e-24 85.7 0.0 6e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK70097.1 - 2.7e-16 60.8 11.2 3.3e-16 60.6 11.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK70097.1 - 6e-07 29.0 0.0 9.1e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 ABK70097.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family GCS2 PF04107.13 ABK70098.1 - 1.1e-52 179.2 0.1 1.8e-52 178.5 0.1 1.3 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) GATase_2 PF00310.21 ABK70099.1 - 4.5e-165 549.5 0.0 5.7e-165 549.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 ABK70099.1 - 1.4e-150 501.5 0.0 2.3e-147 491.0 0.0 2.7 3 0 0 3 3 3 2 Conserved region in glutamate synthase Glu_syn_central PF04898.14 ABK70099.1 - 8.2e-113 376.5 0.0 1.3e-112 375.9 0.0 1.3 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.19 ABK70099.1 - 6.8e-80 267.2 0.2 1.3e-79 266.3 0.2 1.4 1 0 0 1 1 1 1 GXGXG motif FMN_dh PF01070.18 ABK70099.1 - 0.0028 16.7 2.3 0.0028 16.7 2.3 2.4 4 0 0 4 4 4 1 FMN-dependent dehydrogenase IMPDH PF00478.25 ABK70099.1 - 0.2 10.6 1.7 18 4.2 0.7 2.9 2 1 1 3 3 3 0 IMP dehydrogenase / GMP reductase domain SMC_N PF02463.19 ABK70100.1 - 1.4e-16 60.6 0.0 1.8e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ABK70100.1 - 2.7e-07 31.3 0.0 3.3e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 ABK70100.1 - 3.6e-05 23.7 0.0 0.00026 20.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 ABK70100.1 - 3.8e-05 23.6 0.0 4.9e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 ABK70100.1 - 0.022 15.3 0.0 0.036 14.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF2813 PF11398.8 ABK70100.1 - 0.05 12.9 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) AAA_29 PF13555.6 ABK70100.1 - 0.082 12.7 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF664 PF04978.12 ABK70100.1 - 0.13 12.7 2.0 5.3 7.4 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF664) Peripla_BP_3 PF13377.6 ABK70101.1 - 1.5e-32 113.2 0.1 2.7e-32 112.4 0.1 1.4 1 0 0 1 1 1 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 ABK70101.1 - 4.9e-28 98.3 0.0 7e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 ABK70101.1 - 3.7e-20 72.6 0.0 8.5e-20 71.4 0.0 1.6 2 0 0 2 2 2 1 Periplasmic binding protein domain LacI PF00356.21 ABK70101.1 - 2.3e-19 68.9 0.6 2.3e-19 68.9 0.6 2.0 3 0 0 3 3 3 1 Bacterial regulatory proteins, lacI family HTH_3 PF01381.22 ABK70101.1 - 0.00021 21.3 0.0 0.00042 20.3 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 ABK70101.1 - 0.00036 20.8 1.1 0.0027 18.0 0.1 2.4 1 1 1 2 2 2 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 ABK70101.1 - 0.0022 17.8 0.0 0.0044 16.9 0.0 1.4 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_Tnp_ISL3 PF13542.6 ABK70101.1 - 0.0051 16.2 0.5 0.16 11.4 0.3 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain of transposase family ISL3 TetR_N PF00440.23 ABK70101.1 - 0.033 14.0 0.2 0.37 10.6 0.1 2.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family Metallophos_2 PF12850.7 ABK70101.1 - 0.12 12.6 0.1 0.19 11.9 0.1 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain HTH_38 PF13936.6 ABK70101.1 - 0.18 11.6 0.3 0.84 9.4 0.0 2.2 3 0 0 3 3 3 0 Helix-turn-helix domain DUF1729 PF08354.10 ABK70103.1 - 9.2e-110 366.8 0.0 1.3e-109 366.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 ABK70103.1 - 2.9e-43 148.6 2.8 5.6e-36 124.6 0.6 3.6 2 1 0 3 3 3 2 Acyl transferase domain ketoacyl-synt PF00109.26 ABK70103.1 - 3.9e-35 121.7 0.3 9.5e-35 120.4 0.3 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 ABK70103.1 - 2.3e-27 95.3 0.1 8.6e-27 93.5 0.1 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain MaoC_dehydratas PF01575.19 ABK70103.1 - 1e-26 92.9 0.0 2.5e-26 91.7 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain DNA_pol_B_N PF18094.1 ABK70103.1 - 1e-23 83.9 2.1 2.9e-23 82.4 2.1 1.9 1 0 0 1 1 1 1 DNA polymerase beta N-terminal domain SAT PF16073.5 ABK70103.1 - 7.1e-12 45.6 0.1 7.1e-12 45.6 0.1 2.7 3 0 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Fas_alpha_ACP PF18325.1 ABK70103.1 - 6.3e-06 26.6 0.0 1.4e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 ABK70103.1 - 6.6e-06 25.9 0.0 1.4e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain adh_short PF00106.25 ABK70103.1 - 2.2e-05 24.0 0.1 0.0015 18.0 0.0 2.6 2 0 0 2 2 2 1 short chain dehydrogenase Thiolase_N PF00108.23 ABK70103.1 - 0.073 12.4 0.1 0.44 9.9 0.1 2.3 2 0 0 2 2 2 0 Thiolase, N-terminal domain PALP PF00291.25 ABK70104.1 - 2.1e-73 247.3 9.5 2.1e-73 247.3 9.5 1.4 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 ABK70104.1 - 8e-28 96.1 0.0 1.4e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 C-terminal regulatory domain of Threonine dehydratase KR PF08659.10 ABK70104.1 - 0.034 14.1 0.0 0.073 13.0 0.0 1.5 1 0 0 1 1 1 0 KR domain DAGK_cat PF00781.24 ABK70104.1 - 0.045 13.4 0.8 0.089 12.4 0.8 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Methyltransf_25 PF13649.6 ABK70106.1 - 4e-17 62.7 0.0 6.2e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABK70106.1 - 4.1e-14 53.0 0.0 6e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABK70106.1 - 1.2e-13 51.1 0.0 1.5e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABK70106.1 - 4.4e-12 46.1 0.0 5.5e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 ABK70106.1 - 8.8e-12 45.1 0.0 1.5e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_12 PF08242.12 ABK70106.1 - 9.5e-11 42.3 0.0 1.7e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 ABK70106.1 - 1.1e-05 25.0 0.0 1.3e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.14 ABK70106.1 - 1.3e-05 24.8 0.0 1.8e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 ABK70106.1 - 2.7e-05 24.2 0.0 3.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 ABK70106.1 - 0.00025 20.6 0.0 0.00033 20.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 ABK70106.1 - 0.0013 18.1 0.0 0.0016 17.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 ABK70106.1 - 0.0071 16.3 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 ABK70106.1 - 0.06 13.0 0.0 0.081 12.5 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) adh_short PF00106.25 ABK70106.1 - 0.091 12.2 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase tRNA_U5-meth_tr PF05958.11 ABK70106.1 - 0.13 11.2 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase DUF732 PF05305.14 ABK70107.1 - 9.4e-19 67.6 1.1 1.1e-18 67.3 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF732) DUF4971 PF16341.5 ABK70107.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4971) ABC_tran PF00005.27 ABK70108.1 - 2e-24 86.6 0.0 2.7e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK70108.1 - 2.6e-07 30.7 1.2 0.0019 18.1 0.2 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ABK70108.1 - 0.0003 21.2 0.2 0.00091 19.7 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 ABK70108.1 - 0.023 14.1 0.0 0.71 9.3 0.0 2.1 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ABK70108.1 - 0.033 14.5 0.1 0.14 12.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ABK70108.1 - 0.098 12.9 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ABK70108.1 - 0.11 13.0 0.0 0.18 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ABK70108.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 ABK70108.1 - 0.12 12.1 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain DUF3584 PF12128.8 ABK70108.1 - 0.12 9.8 0.0 0.18 9.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA PF00004.29 ABK70108.1 - 0.15 12.5 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 ABK70109.1 - 5.8e-29 100.9 0.0 6.8e-29 100.7 0.0 1.0 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 ABK70109.1 - 2.2e-11 43.3 2.4 2.2e-10 40.0 2.4 2.0 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 ABK70109.1 - 8.4e-05 22.2 0.1 0.18 11.3 0.0 2.5 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ABK70109.1 - 0.0013 18.7 0.0 0.19 11.6 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase MobB PF03205.14 ABK70109.1 - 0.0018 18.2 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 ABK70109.1 - 0.0098 16.4 0.0 0.019 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 ABK70109.1 - 0.013 15.3 0.1 0.052 13.3 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1_Xtn PF16897.5 ABK70109.1 - 0.017 15.1 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 ABK70109.1 - 0.019 15.0 0.0 0.037 14.1 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 ABK70109.1 - 0.039 14.3 0.0 0.052 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 ABK70109.1 - 0.049 12.9 0.1 0.085 12.1 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin MnmE_helical PF12631.7 ABK70109.1 - 0.053 13.7 0.0 0.067 13.3 0.0 1.1 1 0 0 1 1 1 0 MnmE helical domain TrwB_AAD_bind PF10412.9 ABK70109.1 - 0.066 12.1 0.1 0.077 11.9 0.1 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 ABK70109.1 - 0.08 12.0 0.0 0.098 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 ABK70109.1 - 0.13 12.8 0.0 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 ABK70109.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 ABK70109.1 - 0.13 11.9 0.3 0.47 10.1 0.3 1.7 1 1 1 2 2 2 0 AAA domain IstB_IS21 PF01695.17 ABK70109.1 - 0.17 11.6 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.27 ABK70109.1 - 0.18 12.3 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter TsaE PF02367.17 ABK70109.1 - 0.18 11.8 0.1 0.27 11.2 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2631 PF10939.8 ABK70110.1 - 1.7e-28 98.2 2.0 2.2e-28 97.8 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2631) DUF3153 PF11353.8 ABK70110.1 - 0.26 10.8 1.4 0.38 10.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3153) LeuA_dimer PF08502.10 ABK70111.1 - 0.001 18.9 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain DUF4350 PF14258.6 ABK70111.1 - 0.055 13.9 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) DDE_Tnp_ISL3 PF01610.17 ABK70112.1 - 3.1e-50 171.1 0.0 4.4e-50 170.6 0.0 1.2 1 0 0 1 1 1 1 Transposase zf-ISL3 PF14690.6 ABK70112.1 - 3.2e-11 43.7 6.9 4.2e-10 40.1 3.8 2.9 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HTH_Tnp_ISL3 PF13542.6 ABK70112.1 - 3.4e-10 39.2 0.3 3.4e-10 39.2 0.3 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain of transposase family ISL3 Rubredoxin_2 PF18073.1 ABK70112.1 - 0.011 15.4 2.1 0.012 15.4 0.2 2.1 2 0 0 2 2 2 0 Rubredoxin metal binding domain SnoaL_2 PF12680.7 ABK70113.1 - 3.8e-11 43.5 0.3 5.6e-11 43.0 0.3 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 ABK70113.1 - 0.012 16.0 0.1 0.028 14.8 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) MM_CoA_mutase PF01642.22 ABK70114.1 - 4e-127 424.9 0.0 5.4e-127 424.4 0.0 1.1 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase OmpA PF00691.20 ABK70114.1 - 0.26 11.7 3.6 8.5 6.8 0.0 3.1 3 0 0 3 3 3 0 OmpA family Abhydrolase_6 PF12697.7 ABK70115.1 - 5.4e-12 46.8 12.1 8.4e-12 46.2 12.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK70115.1 - 2.8e-10 39.9 0.6 4.2e-10 39.3 0.6 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ABK70115.1 - 4.8e-10 39.5 0.1 6.3e-10 39.1 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 ABK70115.1 - 2.6e-05 23.9 0.4 3.9e-05 23.4 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase Peptidase_S9 PF00326.21 ABK70115.1 - 0.0032 17.0 0.1 0.0043 16.6 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family PGAP1 PF07819.13 ABK70115.1 - 0.0071 16.1 0.1 0.01 15.6 0.1 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.7 ABK70115.1 - 0.012 15.4 0.1 0.018 14.8 0.1 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 ABK70115.1 - 0.031 14.4 0.0 0.055 13.6 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Palm_thioest PF02089.15 ABK70115.1 - 0.034 14.0 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF2920 PF11144.8 ABK70115.1 - 0.11 11.6 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) DUF3530 PF12048.8 ABK70115.1 - 0.13 11.7 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) MMPL PF03176.15 ABK70117.1 - 2.3e-216 717.1 27.6 1.2e-108 363.0 7.2 3.1 3 0 0 3 3 3 2 MMPL family TA0956 PF11513.8 ABK70117.1 - 0.083 13.1 1.9 0.5 10.6 0.1 2.4 2 0 0 2 2 2 0 Thermoplasma acidophilum protein TA0956 Prominin PF05478.11 ABK70117.1 - 3 5.7 7.8 0.1 10.5 0.7 2.0 2 0 0 2 2 2 0 Prominin DUF1664 PF07889.12 ABK70117.1 - 8.2 6.5 8.3 3.6 7.7 2.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Orn_Arg_deC_N PF02784.16 ABK70119.1 - 6.6e-59 199.3 0.1 8.3e-59 198.9 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 ABK70119.1 - 1.1e-11 44.7 0.0 2.6e-11 43.6 0.1 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 ABK70119.1 - 0.0035 17.0 1.0 0.0054 16.4 1.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain HTH_18 PF12833.7 ABK70120.1 - 2e-20 72.8 0.9 2e-20 72.8 0.9 1.9 1 1 1 2 2 2 1 Helix-turn-helix domain AraC_binding PF02311.19 ABK70120.1 - 5.4e-18 65.2 0.6 2.6e-17 63.0 0.3 2.1 1 1 1 2 2 2 1 AraC-like ligand binding domain HTH_AraC PF00165.23 ABK70120.1 - 4.8e-12 45.6 0.0 1.3e-06 28.4 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family DNA_primase_S PF01896.19 ABK70121.1 - 0.027 14.5 0.0 0.31 11.1 0.0 2.2 2 0 0 2 2 2 0 DNA primase small subunit Bac_luciferase PF00296.20 ABK70122.1 - 1.5e-49 169.1 3.5 2.4e-49 168.4 3.5 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase AMP-binding PF00501.28 ABK70123.1 - 1.2e-74 251.5 0.0 1.5e-74 251.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK70123.1 - 2.5e-13 50.8 0.6 6.5e-13 49.5 0.6 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain baeRF_family2 PF18844.1 ABK70123.1 - 0.057 13.5 0.7 0.18 11.8 0.4 2.0 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 2 CoA_transf_3 PF02515.17 ABK70125.1 - 1.8e-99 333.4 0.0 2.1e-99 333.1 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III LacAB_rpiB PF02502.18 ABK70126.1 - 2.5e-44 150.6 0.0 2.8e-44 150.5 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.6 ABK70126.1 - 0.02 14.9 0.1 0.04 13.9 0.1 1.6 1 1 0 1 1 1 0 Glycine-rich SFCGS Pkinase PF00069.25 ABK70127.1 - 1.6e-32 112.9 0.0 2.8e-32 112.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ABK70127.1 - 6.7e-16 58.3 0.0 8e-09 35.2 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.22 ABK70127.1 - 1.3e-05 24.9 0.0 6.7e-05 22.6 0.0 1.8 1 1 1 2 2 2 1 RIO1 family Kdo PF06293.14 ABK70127.1 - 2.9e-05 23.5 0.1 5.7e-05 22.6 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ABK70127.1 - 7.9e-05 22.7 9.0 0.023 14.6 1.2 3.0 1 1 2 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ABK70127.1 - 0.0055 15.5 0.0 0.007 15.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase 2CSK_N PF08521.10 ABK70127.1 - 0.013 15.6 0.6 0.031 14.4 0.2 1.9 2 0 0 2 2 2 0 Two-component sensor kinase N-terminal FTA2 PF13095.6 ABK70127.1 - 0.19 11.3 0.2 0.39 10.3 0.0 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 ABK70127.1 - 0.26 10.9 0.0 0.59 9.7 0.0 1.5 1 1 1 2 2 2 0 Choline/ethanolamine kinase TMP-TENI PF02581.17 ABK70128.1 - 5.3e-52 175.8 0.0 6.3e-52 175.5 0.0 1.1 1 0 0 1 1 1 1 Thiamine monophosphate synthase OMPdecase PF00215.24 ABK70128.1 - 0.012 15.3 0.1 0.034 13.8 0.0 1.8 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Thymidylat_synt PF00303.19 ABK70129.1 - 4.8e-120 399.7 0.0 5.4e-120 399.5 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Rossmann-like PF10727.9 ABK70130.1 - 9.6e-65 216.2 2.9 9.6e-65 216.2 2.9 2.5 3 0 0 3 3 3 1 Rossmann-like domain DUF2520 PF10728.9 ABK70130.1 - 9.9e-38 128.8 0.5 1.5e-37 128.2 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2520) F420_oxidored PF03807.17 ABK70130.1 - 4.4e-05 24.0 0.1 0.00012 22.6 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 ABK70130.1 - 0.025 13.9 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 ABK70130.1 - 0.097 12.8 0.1 2.1 8.5 0.0 2.2 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase CBS PF00571.28 ABK70132.1 - 1.4e-13 51.0 2.0 9.7e-08 32.3 0.1 2.2 2 0 0 2 2 2 2 CBS domain Acyl-CoA_dh_1 PF00441.24 ABK70133.1 - 6.9e-43 146.4 3.5 1.4e-42 145.4 3.5 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK70133.1 - 1.1e-20 73.7 0.0 2e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ABK70133.1 - 2.3e-11 44.3 0.2 9.3e-11 42.4 0.2 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ABK70133.1 - 1.1e-10 41.9 1.6 2.1e-10 41.0 1.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MarR PF01047.22 ABK70135.1 - 1.8e-06 27.8 0.0 3.5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 ABK70135.1 - 3.6e-06 26.8 0.5 9.5e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 MarR family HTH_IclR PF09339.10 ABK70135.1 - 0.00024 20.8 0.2 0.00065 19.5 0.1 1.8 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_27 PF13463.6 ABK70135.1 - 0.00038 20.9 0.2 0.00095 19.6 0.1 1.7 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_24 PF13412.6 ABK70135.1 - 0.0044 16.6 0.1 0.0086 15.6 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 ABK70135.1 - 0.0082 16.2 0.1 0.029 14.4 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_5 PF01022.20 ABK70135.1 - 0.015 15.2 0.2 0.046 13.6 0.1 1.9 1 1 1 2 2 2 0 Bacterial regulatory protein, arsR family HxlR PF01638.17 ABK70135.1 - 0.015 15.2 0.0 0.037 13.9 0.0 1.8 2 0 0 2 2 2 0 HxlR-like helix-turn-helix TrmB PF01978.19 ABK70135.1 - 0.071 13.0 0.1 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Fe_dep_repress PF01325.19 ABK70135.1 - 0.14 12.4 0.1 0.35 11.1 0.0 1.7 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain FAD-oxidase_C PF02913.19 ABK70136.1 - 7.6e-45 153.5 0.0 1.4e-44 152.7 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 ABK70136.1 - 6.5e-39 132.9 2.3 1.6e-38 131.6 2.3 1.7 1 0 0 1 1 1 1 FAD binding domain Fer4_8 PF13183.6 ABK70136.1 - 1.2e-09 38.4 3.2 1.8e-09 37.9 1.9 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 ABK70136.1 - 1.7e-07 31.7 0.8 3.5e-07 30.7 0.8 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain CCG PF02754.16 ABK70136.1 - 6.6e-07 29.4 0.0 0.00068 19.8 0.0 2.6 2 0 0 2 2 2 2 Cysteine-rich domain Fer4_7 PF12838.7 ABK70136.1 - 0.0013 19.2 0.7 0.0045 17.5 0.7 2.0 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 ABK70136.1 - 0.057 13.6 3.9 0.4 10.8 1.0 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 ABK70136.1 - 0.4 10.9 3.0 1.3 9.3 3.0 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 ABK70136.1 - 0.88 9.8 3.5 0.82 9.8 0.6 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain GnRH PF00446.17 ABK70136.1 - 1.1 9.8 3.4 4.7 7.8 3.4 2.2 1 0 0 1 1 1 0 Gonadotropin-releasing hormone Fer4_2 PF12797.7 ABK70136.1 - 3.4 8.0 6.9 8.1 6.8 1.8 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4 PF00037.27 ABK70136.1 - 5.8 6.9 6.1 3.2 7.7 1.5 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain ADH_zinc_N_2 PF13602.6 ABK70137.1 - 1.2e-17 65.1 0.3 2.4e-17 64.2 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ABK70137.1 - 1.4e-11 44.5 0.0 3e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ABK70137.1 - 3.3e-10 39.8 0.0 5.7e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 ABK70137.1 - 0.016 15.1 1.5 0.019 14.9 0.1 1.8 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase Semialdhyde_dh PF01118.24 ABK70137.1 - 0.03 14.8 0.0 0.055 13.9 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 ABK70137.1 - 0.073 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 ABK70137.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 ABK70138.1 - 2.8e-48 164.6 60.1 5.8e-44 150.4 44.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Gln-synt_C PF00120.24 ABK70139.1 - 1.1e-134 448.8 0.0 1.3e-134 448.6 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 ABK70139.1 - 5.4e-28 96.5 0.1 1.1e-27 95.6 0.1 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain NMT1 PF09084.11 ABK70140.1 - 7.8e-16 58.7 0.0 1.7e-15 57.6 0.0 1.5 2 0 0 2 2 2 1 NMT1/THI5 like NMT1_2 PF13379.6 ABK70140.1 - 2.4e-10 40.6 0.1 3.6e-10 40.0 0.1 1.2 1 0 0 1 1 1 1 NMT1-like family SBP_bac_3 PF00497.20 ABK70140.1 - 0.00034 20.1 0.0 0.001 18.6 0.0 1.8 2 1 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_3 PF16868.5 ABK70140.1 - 0.0022 17.4 0.0 0.0035 16.8 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family OpuAC PF04069.12 ABK70140.1 - 0.0054 16.3 0.0 0.012 15.2 0.0 1.6 1 1 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system Phosphonate-bd PF12974.7 ABK70140.1 - 0.067 12.8 0.5 0.23 11.0 0.5 2.0 1 1 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein HD PF01966.22 ABK70141.1 - 3.5e-09 36.9 0.1 5.3e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 HD domain Aminotran_1_2 PF00155.21 ABK70142.1 - 6.2e-30 104.6 0.0 8.1e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 ABK70142.1 - 4.8e-15 55.0 1.3 1.6e-14 53.3 0.2 2.6 3 0 0 3 3 3 1 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 ABK70142.1 - 0.00083 19.3 0.1 0.00083 19.3 0.1 1.9 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain Fe_dep_repress PF01325.19 ABK70142.1 - 0.0012 19.0 0.0 0.0025 17.9 0.0 1.5 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Rrf2 PF02082.20 ABK70142.1 - 0.0031 17.8 0.1 0.0098 16.2 0.0 1.8 2 0 0 2 2 2 1 Transcriptional regulator HTH_24 PF13412.6 ABK70142.1 - 0.0062 16.1 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding DegT_DnrJ_EryC1 PF01041.17 ABK70142.1 - 0.02 14.2 0.1 0.036 13.4 0.1 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family MarR_2 PF12802.7 ABK70142.1 - 0.02 14.7 0.2 0.12 12.3 0.2 2.3 1 0 0 1 1 1 0 MarR family HTH_11 PF08279.12 ABK70142.1 - 0.032 14.2 1.2 0.044 13.7 0.0 1.8 2 0 0 2 2 2 0 HTH domain TetR_N PF00440.23 ABK70143.1 - 1.3e-10 40.8 0.2 3.6e-10 39.5 0.2 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_22 PF17928.1 ABK70143.1 - 0.045 14.1 0.8 0.094 13.1 0.1 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DEDD_Tnp_IS110 PF01548.17 ABK70144.1 - 1.4e-18 67.3 0.2 5.9e-18 65.2 0.0 1.9 2 0 0 2 2 2 1 Transposase Transposase_20 PF02371.16 ABK70144.1 - 1.4e-17 63.7 0.2 3.1e-17 62.7 0.2 1.5 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family HTH_19 PF12844.7 ABK70144.1 - 0.0026 17.7 0.0 0.006 16.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Nup54 PF13874.6 ABK70144.1 - 0.1 12.7 0.2 0.19 11.8 0.2 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 HTH_31 PF13560.6 ABK70144.1 - 0.1 12.9 0.0 0.1 12.9 0.0 3.3 4 1 0 4 4 4 0 Helix-turn-helix domain HTH_25 PF13413.6 ABK70144.1 - 0.14 12.0 0.0 0.14 12.0 0.0 2.1 3 0 0 3 3 3 0 Helix-turn-helix domain Methyltransf_31 PF13847.6 ABK70145.1 - 3.2e-27 95.2 0.0 4.5e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABK70145.1 - 2e-17 63.7 0.1 4e-17 62.7 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK70145.1 - 2.6e-17 63.4 0.0 4.8e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABK70145.1 - 1.3e-16 61.0 0.0 3e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABK70145.1 - 5.4e-14 52.4 0.0 8.7e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ABK70145.1 - 1.1e-09 37.9 0.0 1.9e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 ABK70145.1 - 2.2e-08 33.8 0.1 3.5e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 ABK70145.1 - 7e-08 32.1 0.0 1.1e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 ABK70145.1 - 6.9e-07 28.8 0.0 1.1e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain PCMT PF01135.19 ABK70145.1 - 1.9e-06 27.8 0.0 3.3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 ABK70145.1 - 1e-05 25.1 0.0 4.5e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_9 PF08003.11 ABK70145.1 - 0.00012 21.1 0.0 0.00017 20.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) GidB PF02527.15 ABK70145.1 - 0.00024 20.5 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G DREV PF05219.12 ABK70145.1 - 0.00057 19.1 0.0 0.00085 18.5 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_24 PF13578.6 ABK70145.1 - 0.00083 20.4 0.6 0.0024 18.9 0.2 2.1 2 1 0 2 2 2 1 Methyltransferase domain NodS PF05401.11 ABK70145.1 - 0.0018 17.9 0.0 0.0039 16.8 0.0 1.5 2 0 0 2 2 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 ABK70145.1 - 0.0031 17.5 0.0 0.0047 16.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 ABK70145.1 - 0.0053 16.2 0.0 0.0081 15.6 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB PrmA PF06325.13 ABK70145.1 - 0.0072 15.7 0.1 0.011 15.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) HTH_42 PF06224.12 ABK70145.1 - 0.0093 15.5 0.2 0.018 14.6 0.2 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain Methyltransf_18 PF12847.7 ABK70145.1 - 0.044 13.7 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DRE2_N PF16803.5 ABK70145.1 - 0.066 13.5 0.0 4.5 7.5 0.0 2.3 2 0 0 2 2 2 0 Fe-S cluster assembly protein DRE2 N-terminus FtsX PF02687.21 ABK70146.1 - 1.6e-05 25.3 3.6 1.6e-05 25.3 3.6 2.7 2 1 0 2 2 2 1 FtsX-like permease family Ald_Xan_dh_C2 PF02738.18 ABK70147.1 - 5.4e-174 579.7 0.1 6.6e-174 579.4 0.1 1.0 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 ABK70147.1 - 4.1e-37 126.9 0.1 1e-36 125.6 0.1 1.8 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Acyl-CoA_dh_M PF02770.19 ABK70148.1 - 1.2e-10 41.4 0.0 2.3e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ABK70148.1 - 1.5e-07 31.7 5.5 1.5e-07 31.7 5.5 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK70148.1 - 4.5e-05 24.1 0.1 0.0003 21.4 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain MLTR_LBD PF17765.1 ABK70149.1 - 1.4e-41 142.4 1.3 1.4e-41 142.4 1.3 1.5 2 0 0 2 2 2 1 MmyB-like transcription regulator ligand binding domain HTH_31 PF13560.6 ABK70149.1 - 1.2e-16 60.7 3.2 3.1e-16 59.5 3.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain zf-HC2 PF13490.6 ABK70150.1 - 4.4e-09 36.4 3.5 5.9e-09 36.0 1.7 2.0 2 0 0 2 2 2 1 Putative zinc-finger DUF3067 PF11267.8 ABK70150.1 - 0.14 12.8 0.0 0.17 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3067) Guanylate_cyc PF00211.20 ABK70151.1 - 1.1e-17 64.3 0.0 1.7e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain ABC_tran PF00005.27 ABK70152.1 - 7.1e-27 94.6 0.0 1.3e-26 93.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK70152.1 - 6.9e-06 26.1 0.0 0.023 14.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ABK70152.1 - 4.7e-05 23.4 0.0 8.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 ABK70152.1 - 8.1e-05 23.1 0.0 0.00021 21.7 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 ABK70152.1 - 0.0013 18.4 0.3 0.0072 16.1 0.0 2.3 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_22 PF13401.6 ABK70152.1 - 0.0013 19.0 0.1 0.0088 16.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 ABK70152.1 - 0.0036 16.9 0.0 0.0075 15.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 ABK70152.1 - 0.013 15.9 0.0 1.3 9.5 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 ABK70152.1 - 0.02 14.8 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 ABK70152.1 - 0.039 14.0 0.0 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.6 ABK70152.1 - 0.041 14.1 0.0 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 ABK70152.1 - 0.048 13.7 0.1 0.085 12.9 0.1 1.4 1 0 0 1 1 1 0 Dynamin family RNA_helicase PF00910.22 ABK70152.1 - 0.093 13.1 0.0 0.27 11.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase PIF1 PF05970.14 ABK70152.1 - 0.14 11.3 0.0 5.2 6.1 0.0 2.0 2 0 0 2 2 2 0 PIF1-like helicase NACHT PF05729.12 ABK70152.1 - 0.16 11.9 0.3 0.63 9.9 0.1 2.1 3 0 0 3 3 3 0 NACHT domain NB-ARC PF00931.22 ABK70152.1 - 0.16 11.1 0.0 0.46 9.6 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain HTH_18 PF12833.7 ABK70153.1 - 2.3e-15 56.6 0.9 2.3e-15 56.6 0.9 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain DinB_2 PF12867.7 ABK70153.1 - 4.3e-09 36.9 1.6 6.3e-09 36.4 0.3 1.9 2 0 0 2 2 2 1 DinB superfamily HTH_AraC PF00165.23 ABK70153.1 - 3.6e-06 26.9 0.0 0.09 12.9 0.0 2.6 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Ald_Xan_dh_C2 PF02738.18 ABK70154.1 - 3.2e-110 369.2 1.2 2.6e-89 300.2 0.1 2.1 1 1 1 2 2 2 2 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 ABK70154.1 - 2.3e-18 66.5 0.2 5.6e-18 65.3 0.2 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Sugar_tr PF00083.24 ABK70155.1 - 1.4e-43 149.4 11.8 1.9e-43 149.0 11.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ABK70155.1 - 2.3e-19 69.5 26.0 2.7e-19 69.3 26.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 ABK70155.1 - 1.4 7.7 7.7 1.9 7.3 7.7 1.2 1 0 0 1 1 1 0 MFS_1 like family UPF0051 PF01458.17 ABK70157.1 - 2.9e-69 233.1 0.0 3.9e-69 232.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) Hydrolase_4 PF12146.8 ABK70157.1 - 0.1 11.8 0.6 0.16 11.2 0.6 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 CoA_transf_3 PF02515.17 ABK70158.1 - 2.3e-114 382.3 0.1 2.6e-114 382.2 0.1 1.0 1 0 0 1 1 1 1 CoA-transferase family III NfrA_C PF13283.6 ABK70158.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage N adsorption protein A C-term MFS_1 PF07690.16 ABK70159.1 - 2.5e-45 155.0 55.8 4.1e-28 98.3 31.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK70159.1 - 0.2 10.5 32.9 0.045 12.6 15.1 3.2 1 1 0 2 2 2 0 Sugar (and other) transporter Clp_N PF02861.20 ABK70160.1 - 1.6e-24 85.8 8.4 1.8e-13 50.4 2.3 2.6 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_27 PF13514.6 ABK70161.1 - 8.5e-10 38.6 0.0 8.5e-10 38.6 0.0 4.3 2 1 2 4 4 4 1 AAA domain AAA_15 PF13175.6 ABK70161.1 - 1.3e-09 38.3 0.0 1.9e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 ABK70161.1 - 1.1e-07 32.6 0.2 1.3e-06 29.1 0.2 2.8 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 ABK70161.1 - 2.3e-07 30.5 0.3 0.011 15.1 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ABK70161.1 - 0.00018 21.1 0.0 0.0004 20.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF2813 PF11398.8 ABK70161.1 - 0.0004 19.8 1.0 0.0024 17.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2813) DUF2730 PF10805.8 ABK70161.1 - 0.005 16.9 0.8 0.005 16.9 0.8 3.3 4 0 0 4 4 4 1 Protein of unknown function (DUF2730) MRPL52 PF18699.1 ABK70161.1 - 0.42 10.8 1.8 23 5.3 0.0 3.2 2 0 0 2 2 2 0 Mitoribosomal protein mL52 Fib_alpha PF08702.10 ABK70161.1 - 0.7 10.1 4.0 0.59 10.3 0.6 2.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Fez1 PF06818.15 ABK70161.1 - 7 7.0 39.3 0.13 12.7 12.7 4.0 2 2 2 4 4 4 0 Fez1 Peptidase_S15 PF02129.18 ABK70162.1 - 3.6e-59 200.6 0.1 4.6e-59 200.2 0.1 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 ABK70162.1 - 5.6e-26 91.9 0.1 1.1e-25 90.9 0.1 1.4 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S9 PF00326.21 ABK70162.1 - 2.4e-07 30.5 0.2 0.0016 18.0 0.3 2.7 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 ABK70162.1 - 0.062 13.1 0.0 0.26 11.1 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold KASH_CCD PF14662.6 ABK70163.1 - 0.0022 17.9 0.2 0.0033 17.3 0.2 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH YabA PF06156.13 ABK70163.1 - 0.0058 17.2 0.1 0.0091 16.6 0.1 1.4 1 0 0 1 1 1 1 Initiation control protein YabA CENP-H PF05837.12 ABK70163.1 - 0.007 16.8 0.6 0.011 16.2 0.6 1.4 1 0 0 1 1 1 1 Centromere protein H (CENP-H) HOOK PF05622.12 ABK70163.1 - 0.0075 14.5 0.2 0.0077 14.4 0.2 1.0 1 0 0 1 1 1 1 HOOK protein DivIC PF04977.15 ABK70163.1 - 0.013 15.3 2.7 0.022 14.5 2.7 1.3 1 0 0 1 1 1 0 Septum formation initiator TetR_N PF00440.23 ABK70163.1 - 0.041 13.7 1.0 1.6 8.6 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family DUF4795 PF16043.5 ABK70163.1 - 0.048 13.3 0.0 0.052 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) DUF3450 PF11932.8 ABK70163.1 - 0.064 12.5 3.7 0.58 9.4 3.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) ZapB PF06005.12 ABK70163.1 - 0.23 11.9 3.5 0.53 10.8 3.5 1.6 1 1 0 1 1 1 0 Cell division protein ZapB BST2 PF16716.5 ABK70163.1 - 0.37 11.4 4.4 0.66 10.6 3.1 1.9 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 FAD_binding_5 PF00941.21 ABK70166.1 - 7.3e-36 123.5 0.0 9.3e-36 123.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase T2SSE PF00437.20 ABK70167.1 - 2.2e-71 240.1 0.0 2.9e-71 239.7 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein Zeta_toxin PF06414.12 ABK70167.1 - 0.00015 21.1 0.0 0.00035 19.9 0.0 1.5 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.6 ABK70167.1 - 0.00017 21.9 0.2 0.01 16.1 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ABK70167.1 - 0.0031 17.9 0.8 0.011 16.1 0.1 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 ABK70167.1 - 0.0039 17.7 0.4 0.0061 17.1 0.4 1.1 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 ABK70167.1 - 0.0078 16.7 0.0 0.012 16.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 ABK70167.1 - 0.0097 15.6 0.1 0.019 14.7 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain cobW PF02492.19 ABK70167.1 - 0.012 15.2 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TrwB_AAD_bind PF10412.9 ABK70167.1 - 0.049 12.5 0.0 0.089 11.7 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 ABK70167.1 - 0.085 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 ABK70167.1 - 0.17 11.1 0.0 0.22 10.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RsgA_GTPase PF03193.16 ABK70167.1 - 0.18 11.7 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 ABK70167.1 - 0.18 11.3 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region SpoVIF PF14069.6 ABK70167.1 - 0.23 11.3 0.0 0.94 9.3 0.0 1.9 2 0 0 2 2 2 0 Stage VI sporulation protein F Beta-lactamase PF00144.24 ABK70168.1 - 2.8e-63 214.2 3.1 4e-63 213.7 3.1 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 ABK70168.1 - 0.027 14.1 0.0 5 6.7 0.0 2.5 2 0 0 2 2 2 0 Beta-lactamase enzyme family Peptidase_S11 PF00768.20 ABK70168.1 - 0.032 13.7 0.1 0.077 12.4 0.0 1.5 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase DZR PF12773.7 ABK70169.1 - 0.014 15.4 0.2 0.026 14.6 0.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 ABK70169.1 - 0.036 14.1 0.0 0.058 13.4 0.0 1.5 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 ABK70169.1 - 0.046 13.7 0.1 0.088 12.8 0.1 1.5 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein Zn-ribbon_8 PF09723.10 ABK70169.1 - 0.15 12.2 0.7 0.34 11.1 0.7 1.6 1 0 0 1 1 1 0 Zinc ribbon domain HscB_4_cys PF18256.1 ABK70169.1 - 0.52 10.2 6.3 0.47 10.3 0.8 2.5 1 1 1 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif zinc_ribbon_5 PF13719.6 ABK70169.1 - 0.79 9.5 3.6 6.8 6.5 3.7 2.3 1 1 1 2 2 2 0 zinc-ribbon domain CMD PF02627.20 ABK70170.1 - 2.4e-25 88.4 0.2 2.4e-25 88.4 0.2 1.4 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family MerR-DNA-bind PF09278.11 ABK70170.1 - 0.061 13.9 0.0 0.15 12.6 0.0 1.8 1 0 0 1 1 1 0 MerR, DNA binding AMP-binding PF00501.28 ABK70171.1 - 4.3e-117 391.3 0.1 4.9e-117 391.1 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK70171.1 - 2.3e-17 63.7 0.0 5.3e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain E1_dh PF00676.20 ABK70172.1 - 2.3e-87 292.7 0.0 2.8e-87 292.5 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 ABK70172.1 - 3.9e-06 26.3 0.0 1.4e-05 24.5 0.0 1.7 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 ABK70172.1 - 2.9e-05 23.9 0.4 0.00051 19.9 0.4 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.21 ABK70172.1 - 0.00099 18.2 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain ABM PF03992.16 ABK70173.1 - 9.3e-16 57.7 0.1 1.1e-15 57.5 0.1 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase AcetylCoA_hyd_C PF13336.6 ABK70174.1 - 2.1e-54 183.7 0.0 2.9e-54 183.2 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain MurJ PF03023.14 ABK70175.1 - 7.5e-121 403.9 27.8 1.1e-120 403.3 27.8 1.2 1 0 0 1 1 1 1 Lipid II flippase MurJ Peptidase_M78 PF06114.13 ABK70176.1 - 0.0001 22.3 0.0 0.0002 21.3 0.0 1.4 1 1 0 1 1 1 1 IrrE N-terminal-like domain Peptidase_M48 PF01435.18 ABK70176.1 - 0.13 12.1 1.0 0.17 11.7 1.0 1.4 1 1 0 1 1 1 0 Peptidase family M48 HTH_1 PF00126.27 ABK70178.1 - 8.7e-21 73.6 0.4 2e-20 72.5 0.4 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 ABK70178.1 - 0.00018 20.9 0.1 0.066 12.6 0.0 2.4 2 0 0 2 2 2 2 LysR substrate binding domain HTH_20 PF12840.7 ABK70178.1 - 0.057 13.5 0.2 0.52 10.4 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Acyltransferase PF01553.21 ABK70179.1 - 9.6e-16 57.6 0.0 1.8e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase adh_short PF00106.25 ABK70180.1 - 4.9e-40 137.1 3.7 6.5e-40 136.7 3.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK70180.1 - 1.5e-36 126.2 5.6 1.8e-36 125.8 5.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK70180.1 - 4.2e-14 52.8 3.0 1e-13 51.6 3.0 1.5 1 1 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 ABK70180.1 - 0.043 13.9 0.8 0.066 13.3 0.8 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Acyl-CoA_dh_1 PF00441.24 ABK70181.1 - 1.5e-44 151.8 3.0 2.6e-44 151.1 3.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK70181.1 - 4.8e-25 87.6 0.0 1.1e-24 86.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ABK70181.1 - 1.4e-23 83.7 0.3 2.9e-23 82.7 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ABK70181.1 - 7.4e-23 81.3 4.8 7.4e-23 81.3 4.8 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain p450 PF00067.22 ABK70182.1 - 1.1e-55 189.2 0.0 1.5e-55 188.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DctM PF06808.12 ABK70184.1 - 2.1e-112 376.0 55.3 2.5e-112 375.7 55.3 1.0 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporter, DctM component CitMHS PF03600.16 ABK70184.1 - 2.5 7.2 70.3 1.8 7.7 39.0 2.3 1 1 1 2 2 2 0 Citrate transporter Cutinase PF01083.22 ABK70185.1 - 2.5e-45 154.6 1.7 3.2e-45 154.3 1.7 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_2 PF02230.16 ABK70185.1 - 0.00059 19.7 0.1 0.0013 18.5 0.0 1.6 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 ABK70185.1 - 0.023 15.3 3.5 0.028 15.0 3.5 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 ABK70185.1 - 0.062 13.4 0.1 0.097 12.8 0.1 1.2 1 0 0 1 1 1 0 Thioesterase domain BPD_transp_1 PF00528.22 ABK70186.1 - 9.3e-17 61.4 10.9 9.3e-17 61.4 10.9 1.8 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Trp_oprn_chp PF09534.10 ABK70186.1 - 0.23 11.2 3.4 1 9.1 0.2 2.3 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) LexA_DNA_bind PF01726.16 ABK70187.1 - 9.1e-30 102.2 0.1 1.3e-29 101.7 0.1 1.3 1 0 0 1 1 1 1 LexA DNA binding domain Peptidase_S24 PF00717.23 ABK70187.1 - 9.9e-16 57.5 0.0 1.5e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like HTH_27 PF13463.6 ABK70187.1 - 0.00019 21.9 0.1 0.00033 21.1 0.1 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR_2 PF12802.7 ABK70187.1 - 0.0011 18.9 0.2 0.0023 17.8 0.2 1.6 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 ABK70187.1 - 0.0013 18.5 0.1 0.0021 17.8 0.1 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain Pollen_allerg_1 PF01357.21 ABK70187.1 - 0.0066 16.4 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Pollen allergen MarR PF01047.22 ABK70187.1 - 0.0078 16.1 0.0 0.015 15.3 0.0 1.5 1 1 0 1 1 1 1 MarR family HTH_24 PF13412.6 ABK70187.1 - 0.029 13.9 0.1 0.071 12.7 0.1 1.7 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 ABK70187.1 - 0.044 13.8 0.1 0.07 13.1 0.1 1.3 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Sigma70_r4 PF04545.16 ABK70187.1 - 0.05 13.1 0.0 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_20 PF12840.7 ABK70187.1 - 0.069 13.2 0.1 0.23 11.6 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_6 PF01418.17 ABK70187.1 - 0.19 11.7 0.0 0.33 11.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family FaeA PF04703.12 ABK70187.1 - 0.19 12.1 0.4 0.37 11.2 0.0 1.6 2 0 0 2 2 1 0 FaeA-like protein CobN-Mg_chel PF02514.16 ABK70187.1 - 0.25 9.1 0.0 0.32 8.7 0.0 1.1 1 0 0 1 1 1 0 CobN/Magnesium Chelatase Epimerase PF01370.21 ABK70188.1 - 4.4e-27 95.1 0.0 9e-27 94.1 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ABK70188.1 - 8.7e-22 77.9 0.0 1.2e-21 77.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ABK70188.1 - 5e-16 58.5 0.0 6.3e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 ABK70188.1 - 5.4e-16 59.0 0.0 8.8e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 ABK70188.1 - 6.8e-08 32.0 0.0 0.009 15.2 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein NmrA PF05368.13 ABK70188.1 - 1.3e-07 31.4 0.0 2.7e-07 30.4 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family KR PF08659.10 ABK70188.1 - 0.00074 19.5 0.5 0.0049 16.8 0.2 2.4 2 1 0 2 2 2 1 KR domain ATP-synt_DE_N PF02823.16 ABK70189.1 - 4.1e-23 81.1 0.2 4.9e-23 80.8 0.2 1.1 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain S-AdoMet_synt_C PF02773.16 ABK70190.1 - 1.7e-65 219.1 0.0 2.9e-65 218.5 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 ABK70190.1 - 2e-43 147.5 0.0 9.9e-43 145.2 0.0 2.0 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 ABK70190.1 - 2.4e-41 140.4 0.0 5.5e-41 139.3 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 ABK70190.1 - 0.042 12.6 0.0 0.082 11.7 0.0 1.4 2 0 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) AMP-binding PF00501.28 ABK70191.1 - 4.6e-174 579.0 0.1 5.7e-87 292.0 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 ABK70191.1 - 1.1e-116 390.3 0.0 6.8e-86 288.8 0.0 2.1 2 0 0 2 2 2 2 Condensation domain NAD_binding_4 PF07993.12 ABK70191.1 - 1.3e-66 224.5 0.0 2e-66 223.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 ABK70191.1 - 2.5e-27 95.0 0.8 1.2e-14 54.3 0.2 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 ABK70191.1 - 5.9e-22 78.4 0.8 3.4e-10 40.7 0.1 3.4 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Epimerase PF01370.21 ABK70191.1 - 3.6e-07 29.9 0.0 6.8e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ABK70191.1 - 0.071 12.5 0.0 0.23 10.8 0.0 1.7 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF664 PF04978.12 ABK70191.1 - 0.32 11.4 2.9 26 5.2 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF664) Nitroreductase PF00881.24 ABK70192.1 - 1.9e-30 106.1 0.4 2.3e-30 105.9 0.4 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 ABK70192.1 - 0.00051 19.7 0.0 0.57 9.7 0.2 2.7 2 1 1 3 3 3 2 Putative TM nitroreductase G_glu_transpept PF01019.21 ABK70193.1 - 9.3e-124 414.0 0.0 1.1e-123 413.8 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Aldedh PF00171.22 ABK70194.1 - 9.8e-139 462.8 0.7 1.1e-138 462.6 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ppx-GppA PF02541.16 ABK70196.1 - 6.9e-88 294.8 0.0 8e-88 294.6 0.0 1.0 1 0 0 1 1 1 1 Ppx/GppA phosphatase family DUF3180 PF11377.8 ABK70197.1 - 0.0087 16.2 1.0 0.048 13.8 1.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3180) PBP_like_2 PF12849.7 ABK70198.1 - 3.4e-55 187.7 11.1 4.6e-55 187.3 11.1 1.1 1 0 0 1 1 1 1 PBP superfamily domain SBP_bac_1 PF01547.25 ABK70198.1 - 1.8e-09 38.0 12.3 2.3e-09 37.6 12.3 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein PBP_like PF12727.7 ABK70198.1 - 1.3e-07 30.9 0.1 4e-07 29.3 0.1 1.9 1 1 0 1 1 1 1 PBP superfamily domain GCS2 PF04107.13 ABK70200.1 - 0.00011 21.6 0.2 0.068 12.5 0.1 2.3 2 0 0 2 2 2 2 Glutamate-cysteine ligase family 2(GCS2) adh_short_C2 PF13561.6 ABK70201.1 - 1.8e-54 184.8 0.4 2.1e-54 184.6 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK70201.1 - 1.7e-40 138.5 0.1 2.2e-40 138.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK70201.1 - 1.1e-13 51.5 0.7 2.5e-13 50.3 0.7 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK70201.1 - 7.9e-07 28.8 0.1 1.5e-06 27.9 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ABK70201.1 - 9.1e-05 21.6 0.1 0.00013 21.1 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ABK70201.1 - 0.0022 17.5 0.1 0.0054 16.2 0.0 1.8 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ABK70201.1 - 0.0058 15.8 0.0 0.014 14.5 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 ABK70201.1 - 0.019 14.0 0.1 0.04 13.0 0.1 1.6 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_10 PF13460.6 ABK70201.1 - 0.083 12.8 0.2 0.14 12.0 0.2 1.3 1 0 0 1 1 1 0 NAD(P)H-binding NmrA PF05368.13 ABK70201.1 - 0.13 11.9 0.1 0.22 11.0 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family HTH_Tnp_1 PF01527.20 ABK70202.1 - 2.5e-07 30.9 4.8 9.9e-07 29.0 4.8 1.8 1 1 0 1 1 1 1 Transposase HTH_28 PF13518.6 ABK70202.1 - 0.0093 16.1 0.2 0.019 15.1 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_17 PF12728.7 ABK70202.1 - 0.023 14.9 0.1 0.057 13.6 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain Aminotran_3 PF00202.21 ABK70203.1 - 1.1e-62 212.0 0.0 1.5e-62 211.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III HIT PF01230.23 ABK70204.1 - 1.1e-24 87.1 0.0 1.3e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 ABK70204.1 - 2.6e-12 47.2 0.0 3.1e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding AA_permease_2 PF13520.6 ABK70205.1 - 2.3e-37 128.8 51.0 2.9e-37 128.5 51.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ABK70205.1 - 1.5e-20 73.3 41.0 2.4e-20 72.6 41.0 1.3 1 1 0 1 1 1 1 Amino acid permease MIG-14_Wnt-bd PF06664.12 ABK70205.1 - 0.19 10.9 7.1 0.021 14.1 1.4 2.3 1 1 0 2 2 2 0 Wnt-binding factor required for Wnt secretion DUF3464 PF11947.8 ABK70205.1 - 3.3 7.4 15.1 3 7.6 0.7 3.7 3 0 0 3 3 3 0 Photosynthesis affected mutant 68 DUF417 PF04224.12 ABK70207.1 - 0.096 12.2 0.9 0.44 10.1 0.8 2.1 1 1 0 1 1 1 0 Protein of unknown function, DUF417 Nramp PF01566.18 ABK70208.1 - 4.1e-112 374.7 21.1 5.2e-112 374.4 21.1 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Pyr_redox_2 PF07992.14 ABK70209.1 - 9.5e-09 34.9 0.0 1.3e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ABK70209.1 - 3.6e-08 33.5 0.8 1.5e-05 25.1 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ABK70209.1 - 1.5e-05 24.8 0.4 0.013 15.1 0.0 3.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ABK70209.1 - 0.0013 18.2 0.0 0.0044 16.4 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 ABK70209.1 - 0.0027 17.0 0.0 0.026 13.8 0.0 2.1 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 ABK70209.1 - 0.0038 16.6 0.1 0.11 11.8 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 ABK70209.1 - 0.0041 16.3 0.0 0.093 11.9 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 ABK70209.1 - 0.0056 17.2 0.1 0.73 10.4 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ABK70209.1 - 0.014 14.5 0.0 1.9 7.4 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein HI0933_like PF03486.14 ABK70209.1 - 0.014 14.1 0.1 1.2 7.8 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 ABK70209.1 - 0.027 14.5 0.6 0.95 9.4 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.22 ABK70209.1 - 0.073 12.1 0.1 6.7 5.7 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 ABK70209.1 - 0.11 11.7 0.0 0.99 8.6 0.0 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ABK70209.1 - 0.16 11.1 0.1 7 5.8 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain MDMPI_N PF11716.8 ABK70211.1 - 3.4e-06 27.8 6.6 3.4e-06 27.8 6.6 2.8 2 1 0 2 2 2 1 Mycothiol maleylpyruvate isomerase N-terminal domain Aminotran_5 PF00266.19 ABK70212.1 - 1.4e-36 126.3 0.0 1.8e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 ABK70212.1 - 0.0057 15.2 0.0 0.0077 14.8 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 ABK70212.1 - 0.081 12.2 0.0 0.18 11.0 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase Aldo_ket_red PF00248.21 ABK70213.1 - 8.5e-73 245.1 0.0 9.6e-73 244.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DLH PF01738.18 ABK70214.1 - 1.2e-51 175.4 0.0 1.3e-51 175.2 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 ABK70214.1 - 2.4e-05 24.4 0.0 0.002 18.1 0.0 2.2 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 ABK70214.1 - 0.0073 16.0 0.0 0.012 15.2 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 ABK70214.1 - 0.0087 15.7 0.0 0.025 14.2 0.0 1.7 1 1 0 1 1 1 1 Putative esterase Chlorophyllase PF07224.11 ABK70214.1 - 0.047 12.7 0.0 0.089 11.8 0.0 1.5 1 1 0 1 1 1 0 Chlorophyllase adh_short PF00106.25 ABK70215.1 - 6e-41 140.0 0.3 7.2e-41 139.8 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK70215.1 - 7.6e-33 114.0 0.0 1e-32 113.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK70215.1 - 7.8e-07 29.2 2.7 3.8e-06 26.9 2.7 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK70215.1 - 0.00019 21.0 0.5 0.00037 20.1 0.5 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ABK70215.1 - 0.00071 18.7 0.5 0.0013 17.8 0.5 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family ADH_zinc_N PF00107.26 ABK70215.1 - 0.055 13.5 0.3 0.087 12.8 0.3 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase TrkA_N PF02254.18 ABK70215.1 - 0.059 13.6 0.8 0.1 12.8 0.8 1.4 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.19 ABK70215.1 - 0.15 11.2 0.3 0.19 10.9 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain ECH_1 PF00378.20 ABK70216.1 - 5.9e-42 143.7 0.0 6.9e-42 143.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK70216.1 - 7.1e-21 75.0 0.1 2.4e-20 73.3 0.1 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Ribonuc_red_lgC PF02867.15 ABK70217.1 - 6.8e-147 490.2 1.3 3.9e-145 484.3 1.3 2.2 1 1 0 1 1 1 1 Ribonucleotide reductase, barrel domain RNR_N PF08343.10 ABK70217.1 - 1.1e-33 115.1 11.1 2.5e-33 114.0 9.4 2.3 2 0 0 2 2 2 1 Ribonucleotide reductase N-terminal Ribonuc_red_lgN PF00317.21 ABK70217.1 - 7.9e-13 48.2 0.1 3.7e-12 46.1 0.0 2.2 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain Fib_succ_major PF09603.10 ABK70217.1 - 0.039 14.6 0.0 0.076 13.6 0.0 1.6 1 0 0 1 1 1 0 Fibrobacter succinogenes major domain (Fib_succ_major) T4bSS_IcmS PF12608.8 ABK70217.1 - 0.1 12.9 0.2 0.26 11.6 0.2 1.6 1 0 0 1 1 1 0 Type IVb secretion, IcmS, effector-recruitment MFS_1 PF07690.16 ABK70218.1 - 1.7e-31 109.5 101.3 5.7e-28 97.8 56.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ABK70218.1 - 1.9e-09 37.3 51.5 2.4e-09 37.0 51.5 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 ABK70218.1 - 8.2e-08 31.5 13.4 8.2e-08 31.5 13.4 2.2 1 1 0 2 2 2 1 Sugar (and other) transporter Acyltransferase PF01553.21 ABK70219.1 - 2.5e-21 75.7 0.0 3.6e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase BPD_transp_2 PF02653.16 ABK70220.1 - 3.4e-39 134.6 43.7 3.4e-39 134.6 43.7 1.4 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component stn_TNFRSF12A PF12191.8 ABK70220.1 - 3 8.1 9.4 0.27 11.5 1.8 2.9 2 1 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain TetR_C_16 PF17920.1 ABK70221.1 - 2.3e-27 95.3 0.0 4.1e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK70221.1 - 5.8e-16 58.0 0.3 5e-15 55.0 0.6 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family Helicase_C_3 PF13625.6 ABK70222.1 - 1.1e-46 158.1 0.4 2e-46 157.3 0.4 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 ABK70222.1 - 1.6e-42 145.5 0.0 2.3e-42 144.9 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 ABK70222.1 - 2.1e-13 50.6 0.0 3.4e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ABK70222.1 - 3.1e-10 40.4 0.0 6.2e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 ABK70222.1 - 1.3e-05 24.1 0.0 6.3e-05 21.8 0.0 1.6 1 1 1 2 2 2 1 SNF2 family N-terminal domain DEAD PF00270.29 ABK70222.1 - 0.045 13.5 0.0 0.083 12.7 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase DEAD_assoc PF08494.11 ABK70223.1 - 3.2e-73 245.6 0.0 6.6e-73 244.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/H associated DEAD PF00270.29 ABK70223.1 - 5.6e-28 97.9 0.0 1e-27 97.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ABK70223.1 - 1.1e-13 51.4 0.0 5.6e-12 46.0 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HTH_42 PF06224.12 ABK70223.1 - 1.1e-07 31.7 8.8 1.1e-07 31.7 8.8 3.2 3 1 0 3 3 3 2 Winged helix DNA-binding domain ResIII PF04851.15 ABK70223.1 - 2.7e-06 27.5 0.0 5.5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.6 ABK70223.1 - 0.0063 16.1 0.2 0.037 13.6 0.2 2.3 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 ABK70223.1 - 0.012 15.0 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.6 ABK70223.1 - 0.066 13.5 0.1 0.47 10.7 0.1 2.3 1 1 0 1 1 1 0 AAA domain LCM PF04072.14 ABK70224.1 - 5.4e-62 209.1 0.4 7.5e-62 208.6 0.4 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase SIMPL PF04402.14 ABK70225.1 - 1.1e-44 153.2 5.8 1.3e-44 153.0 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) RexA PF15969.5 ABK70225.1 - 0.048 13.2 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 Intracellular sensor of Lambda phage, Abi component YbaB_DNA_bd PF02575.16 ABK70225.1 - 0.12 12.6 0.9 2.7 8.3 0.1 2.5 2 0 0 2 2 2 0 YbaB/EbfC DNA-binding family Abhydrolase_3 PF07859.13 ABK70226.1 - 3.4e-22 79.4 2.1 3.4e-22 79.4 2.1 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ABK70226.1 - 8.5e-13 48.3 0.0 1.1e-08 34.8 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 ABK70226.1 - 1.1e-11 44.4 0.2 8.3e-11 41.4 0.2 1.9 1 1 0 1 1 1 1 Carboxylesterase family Hydrolase_4 PF12146.8 ABK70226.1 - 4.3e-05 22.9 0.4 0.0078 15.5 0.0 2.4 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 ABK70226.1 - 0.0019 18.3 0.0 0.0054 16.8 0.0 1.7 2 0 0 2 2 2 1 TAP-like protein DLH PF01738.18 ABK70226.1 - 0.0025 17.4 0.0 0.037 13.6 0.0 2.3 2 1 0 2 2 2 1 Dienelactone hydrolase family Esterase_phd PF10503.9 ABK70226.1 - 0.0038 16.7 2.1 0.82 9.1 0.0 2.8 3 0 0 3 3 3 2 Esterase PHB depolymerase Peptidase_S15 PF02129.18 ABK70226.1 - 0.014 15.0 0.2 0.088 12.4 0.2 2.2 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 ABK70226.1 - 0.021 14.8 0.0 0.46 10.4 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal LIP PF03583.14 ABK70226.1 - 0.032 13.6 0.0 0.43 9.9 0.0 2.0 1 1 0 2 2 2 0 Secretory lipase rve_3 PF13683.6 ABK70227.1 - 6e-23 80.4 1.2 1.9e-21 75.6 0.6 2.4 2 0 0 2 2 2 1 Integrase core domain rve PF00665.26 ABK70227.1 - 1e-20 74.1 0.0 2.1e-19 69.8 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain HTH_21 PF13276.6 ABK70227.1 - 2.7e-10 40.2 1.7 6.7e-10 39.0 1.7 1.7 1 0 0 1 1 1 1 HTH-like domain rve_2 PF13333.6 ABK70227.1 - 0.0047 17.1 0.1 0.0084 16.3 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain LysR_substrate PF03466.20 ABK70228.1 - 7.3e-32 110.4 4.4 1e-31 110.0 4.4 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 ABK70228.1 - 4.3e-23 81.0 2.2 1.1e-22 79.8 2.2 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_Tnp_ISL3 PF13542.6 ABK70228.1 - 0.011 15.2 0.1 0.084 12.3 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 MarR_2 PF12802.7 ABK70228.1 - 0.016 15.1 0.1 0.05 13.5 0.1 1.9 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.6 ABK70228.1 - 0.027 14.0 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 ABK70228.1 - 0.055 13.3 1.0 0.11 12.3 0.1 2.0 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain PknH_C PF14032.6 ABK70229.1 - 1.8e-42 145.4 1.1 2.1e-42 145.1 0.3 1.5 2 0 0 2 2 2 1 PknH-like extracellular domain Bac_luciferase PF00296.20 ABK70230.1 - 3.4e-46 158.1 7.6 4.3e-46 157.8 7.6 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase KdpC PF02669.15 ABK70231.1 - 3.2e-60 203.1 0.1 1.2e-33 116.5 0.1 2.1 2 0 0 2 2 2 2 K+-transporting ATPase, c chain ADH_N PF08240.12 ABK70232.1 - 1.2e-27 95.9 4.5 1.9e-27 95.3 4.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ABK70232.1 - 6.7e-18 64.9 0.0 1.1e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ABK70232.1 - 2.2e-06 27.1 0.1 4e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ABK70232.1 - 0.00011 21.6 0.0 0.00018 20.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 ABK70232.1 - 0.00033 21.7 0.0 0.00059 20.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.6 ABK70232.1 - 0.014 15.8 0.0 0.026 15.0 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 ABK70232.1 - 0.016 15.5 0.1 0.052 13.8 0.1 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 ABK70232.1 - 0.022 14.9 0.0 0.036 14.3 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 ABK70232.1 - 0.068 13.1 0.4 0.11 12.4 0.1 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 ABK70232.1 - 0.091 12.1 1.5 4.5 6.6 2.4 2.2 1 1 1 2 2 2 0 ThiF family MMR_HSR1 PF01926.23 ABK70233.1 - 1.5e-47 160.4 0.1 1.8e-22 79.6 0.0 2.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.6 ABK70233.1 - 4.2e-27 94.3 0.1 9.5e-27 93.1 0.1 1.6 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.18 ABK70233.1 - 6.9e-27 93.9 0.0 2.5e-14 53.1 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 ABK70233.1 - 7.1e-22 77.9 0.4 2.1e-08 33.9 0.0 5.0 3 2 0 3 3 3 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ABK70233.1 - 1.8e-12 47.5 0.0 0.018 15.0 0.0 3.4 3 0 0 3 3 3 3 RsgA GTPase Dynamin_N PF00350.23 ABK70233.1 - 1.1e-10 41.8 0.1 0.03 14.4 0.0 4.1 3 1 1 4 4 4 2 Dynamin family AIG1 PF04548.16 ABK70233.1 - 1.7e-09 37.4 0.0 1.7e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 AIG1 family Roc PF08477.13 ABK70233.1 - 1.5e-07 31.7 0.1 0.009 16.2 0.0 3.2 2 2 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ABK70233.1 - 2.6e-06 27.2 0.0 0.0047 16.5 0.0 3.1 2 2 0 2 2 2 2 Ras family MeaB PF03308.16 ABK70233.1 - 2.8e-06 26.5 1.2 0.26 10.2 0.3 4.0 3 1 1 4 4 4 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 ABK70233.1 - 7.3e-06 26.5 4.0 0.083 13.3 0.6 3.4 2 2 0 2 2 2 2 AAA ATPase domain cobW PF02492.19 ABK70233.1 - 1.9e-05 24.3 2.0 0.53 9.9 0.0 3.9 3 1 0 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 ABK70233.1 - 4.3e-05 24.0 0.0 0.45 11.0 0.0 2.5 3 0 0 3 3 2 2 ABC transporter TniB PF05621.11 ABK70233.1 - 6.1e-05 22.5 0.0 0.42 10.0 0.0 2.6 3 0 0 3 3 3 2 Bacterial TniB protein AAA_22 PF13401.6 ABK70233.1 - 0.00045 20.5 0.0 0.28 11.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 ABK70233.1 - 0.0019 18.5 0.0 0.33 11.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 ABK70233.1 - 0.0026 17.7 0.3 0.13 12.2 0.3 2.5 2 1 0 2 2 2 1 P-loop Nucleotide Kinase3 AAA_24 PF13479.6 ABK70233.1 - 0.0032 17.2 0.0 1.9 8.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain NTPase_1 PF03266.15 ABK70233.1 - 0.0039 17.1 0.0 0.35 10.8 0.0 2.5 2 0 0 2 2 2 1 NTPase AAA_18 PF13238.6 ABK70233.1 - 0.0043 17.6 0.0 3 8.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ABK70233.1 - 0.0084 16.3 0.1 1.2 9.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 ABK70233.1 - 0.0089 16.4 0.0 6.8 7.1 0.0 2.4 2 0 0 2 2 2 0 RNA helicase PduV-EutP PF10662.9 ABK70233.1 - 0.0092 15.7 0.0 11 5.8 0.0 3.6 4 1 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 ABK70233.1 - 0.015 14.7 0.0 3.8 6.9 0.0 2.6 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit Arf PF00025.21 ABK70233.1 - 0.025 14.0 0.4 6.5 6.2 0.0 3.2 2 2 0 2 2 2 0 ADP-ribosylation factor family ATPase_2 PF01637.18 ABK70233.1 - 0.031 14.2 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 ABK70233.1 - 0.038 13.2 0.0 0.99 8.5 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_29 PF13555.6 ABK70233.1 - 0.048 13.4 0.0 7 6.5 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA PF00004.29 ABK70233.1 - 0.1 13.1 0.0 11 6.5 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 ABK70233.1 - 0.13 12.2 0.0 22 4.9 0.0 3.0 3 0 0 3 3 3 0 NACHT domain GBP PF02263.19 ABK70233.1 - 0.16 11.2 0.0 9.8 5.3 0.0 2.3 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain MMR_HSR1_Xtn PF16897.5 ABK70233.1 - 0.2 11.7 0.0 6.8 6.8 0.0 2.3 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain Proteasome PF00227.26 ABK70234.1 - 6.2e-27 94.3 0.0 8.5e-27 93.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit MCH PF02289.16 ABK70234.1 - 0.037 13.3 0.1 0.064 12.5 0.1 1.3 1 0 0 1 1 1 0 Cyclohydrolase (MCH) Phytase-like PF13449.6 ABK70235.1 - 2e-46 159.2 3.6 3e-44 152.1 0.4 3.2 2 1 0 3 3 3 2 Esterase-like activity of phytase PQQ PF01011.21 ABK70235.1 - 0.09 12.7 3.1 3.4 7.8 0.1 3.6 3 0 0 3 3 3 0 PQQ enzyme repeat TLP1_add_C PF18313.1 ABK70236.1 - 3e-20 72.0 0.1 5.5e-20 71.1 0.1 1.5 1 0 0 1 1 1 1 Thiolase-like protein type 1 additional C-terminal domain Thiolase_N PF00108.23 ABK70236.1 - 0.086 12.2 0.0 0.65 9.3 0.0 2.1 1 1 0 1 1 1 0 Thiolase, N-terminal domain DUF2560 PF10834.8 ABK70236.1 - 0.18 12.0 0.0 0.39 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2560) DUF3558 PF12079.8 ABK70238.1 - 1.2e-29 103.5 5.5 1.5e-29 103.2 5.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3558) DUF2220 PF09983.9 ABK70239.1 - 8.2e-58 194.7 0.0 1.2e-57 194.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria C-term(DUF2220) DUF3322 PF11795.8 ABK70239.1 - 4.2e-52 176.9 0.4 6.3e-52 176.3 0.0 1.5 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria N-term (DUF3322) DUF2399 PF09664.10 ABK70239.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) TctA PF01970.16 ABK70240.1 - 2.2e-148 494.4 36.6 2.2e-148 494.4 36.6 1.6 2 0 0 2 2 2 1 Tripartite tricarboxylate transporter TctA family SecE PF00584.20 ABK70240.1 - 5.3 7.1 0.0 5.3 7.1 0.0 4.0 4 0 0 4 4 4 0 SecE/Sec61-gamma subunits of protein translocation complex DUF3117 PF11314.8 ABK70241.1 - 1.1e-28 98.7 4.2 1.2e-28 98.6 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3117) DUF2207 PF09972.9 ABK70242.1 - 0.79 8.4 1.8 0.88 8.3 1.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1072 PF06380.11 ABK70242.1 - 1.1 9.1 9.6 5.1 7.1 0.9 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1072) GATase_2 PF00310.21 ABK70243.1 - 6.2e-182 605.0 0.0 7.9e-182 604.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 ABK70243.1 - 9.8e-155 515.2 0.0 6.7e-153 509.2 0.0 2.3 2 0 0 2 2 2 2 Conserved region in glutamate synthase Glu_syn_central PF04898.14 ABK70243.1 - 5.9e-116 386.8 0.0 8.9e-116 386.2 0.0 1.3 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.19 ABK70243.1 - 2.2e-83 278.5 3.0 3.5e-83 277.9 3.0 1.3 1 0 0 1 1 1 1 GXGXG motif FMN_dh PF01070.18 ABK70243.1 - 0.13 11.3 6.4 0.06 12.4 1.6 2.5 3 0 0 3 3 3 0 FMN-dependent dehydrogenase PAS_9 PF13426.7 ABK70244.1 - 7.5e-09 35.8 0.0 9.8e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 ABK70244.1 - 9.6e-07 28.8 0.0 1.6e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 PAS fold PAS_4 PF08448.10 ABK70244.1 - 5.6e-06 26.6 0.0 9.1e-06 25.9 0.0 1.4 1 1 0 1 1 1 1 PAS fold PAS_8 PF13188.7 ABK70244.1 - 9.7e-06 25.5 0.0 1.7e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 ABK70244.1 - 0.15 12.4 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 PAS fold SLT_2 PF13406.6 ABK70245.1 - 7.6e-09 35.2 5.6 2.2e-07 30.4 0.3 2.9 2 1 1 3 3 3 2 Transglycosylase SLT domain SLT PF01464.20 ABK70245.1 - 0.0088 15.7 0.0 0.024 14.3 0.0 1.9 1 1 0 1 1 1 1 Transglycosylase SLT domain DUF1824 PF08854.10 ABK70245.1 - 0.19 11.6 0.0 0.47 10.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1824) EF-hand_1 PF00036.32 ABK70245.1 - 0.23 11.1 1.0 0.84 9.3 0.4 2.1 2 0 0 2 2 2 0 EF hand EF-hand_5 PF13202.6 ABK70245.1 - 0.37 10.4 1.5 0.51 9.9 0.4 1.8 2 0 0 2 2 2 0 EF hand Ring_hydroxyl_A PF00848.19 ABK70246.1 - 3.4e-21 76.2 4.4 8.7e-21 74.9 4.4 1.7 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 ABK70246.1 - 2e-13 50.1 0.1 3.5e-13 49.3 0.1 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Glyoxalase_4 PF13669.6 ABK70247.1 - 1e-20 74.1 0.0 1.3e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 ABK70247.1 - 4.9e-05 23.5 0.1 0.00024 21.3 0.1 1.8 1 1 0 1 1 1 1 Glyoxalase-like domain MFS_1 PF07690.16 ABK70248.1 - 1.8e-57 194.9 49.1 1.7e-54 185.1 43.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ABK70248.1 - 1.4e-09 37.7 3.7 1.4e-09 37.7 3.7 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF1269 PF06897.12 ABK70248.1 - 0.014 15.6 0.4 0.057 13.7 0.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) MFS_3 PF05977.13 ABK70248.1 - 0.85 7.9 28.5 0.24 9.8 4.5 2.7 2 1 1 3 3 3 0 Transmembrane secretion effector GTA_holin_3TM PF11351.8 ABK70248.1 - 5.9 7.5 8.8 16 6.0 2.3 2.9 2 1 0 2 2 2 0 Holin of 3TMs, for gene-transfer release OATP PF03137.20 ABK70248.1 - 8.2 4.6 13.6 1.1 7.5 3.1 3.0 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Cupin_2 PF07883.11 ABK70249.1 - 2.2e-14 52.9 0.5 3.7e-14 52.2 0.5 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 ABK70249.1 - 0.00092 18.8 1.3 0.0038 16.8 0.7 1.9 1 1 1 2 2 2 1 Cupin MannoseP_isomer PF01050.18 ABK70249.1 - 0.011 15.7 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Cupin_6 PF12852.7 ABK70249.1 - 0.018 14.8 0.3 0.039 13.7 0.2 1.6 1 1 1 2 2 2 0 Cupin Cupin_3 PF05899.12 ABK70249.1 - 0.059 13.1 0.4 0.71 9.6 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF861) Rib PF08428.10 ABK70249.1 - 0.077 13.0 1.8 2.3 8.2 0.2 2.3 2 1 0 2 2 2 0 Rib/alpha-like repeat PhzC-PhzF PF02567.16 ABK70250.1 - 7.3e-37 127.4 0.0 1e-36 126.9 0.0 1.2 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Trp_ring PF18669.1 ABK70250.1 - 0.077 13.2 0.1 0.22 11.7 0.1 1.7 1 0 0 1 1 1 0 Trimeric autotransporter adhesin Trp ring domain FGE-sulfatase PF03781.16 ABK70251.1 - 2.4e-56 191.2 1.8 4.1e-56 190.4 1.8 1.3 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 ABK70251.1 - 4.4e-18 66.0 5.8 4.4e-18 66.0 5.8 2.3 2 1 0 2 2 2 1 DinB superfamily DUF2236 PF09995.9 ABK70252.1 - 1e-35 124.0 6.6 1e-35 124.0 6.6 1.3 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) Transglut_core3 PF13471.6 ABK70252.1 - 0.37 10.7 2.4 1.3 8.9 0.0 2.4 2 1 0 2 2 2 0 Transglutaminase-like superfamily HTH_20 PF12840.7 ABK70253.1 - 4.3e-06 26.7 0.6 7.5e-06 25.9 0.1 1.7 2 0 0 2 2 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 ABK70253.1 - 6.8e-06 25.8 0.6 2.5e-05 24.0 0.1 2.2 3 0 0 3 3 3 1 IclR helix-turn-helix domain HTH_11 PF08279.12 ABK70253.1 - 6.5e-05 22.8 0.0 0.0003 20.7 0.0 1.9 2 0 0 2 2 2 1 HTH domain MarR_2 PF12802.7 ABK70253.1 - 0.0001 22.1 0.7 0.00026 20.8 0.4 1.8 2 0 0 2 2 2 1 MarR family HTH_24 PF13412.6 ABK70253.1 - 0.00038 20.0 0.0 0.00074 19.0 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_12 PF08461.10 ABK70253.1 - 0.00056 19.8 0.0 0.0014 18.5 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain HTH_5 PF01022.20 ABK70253.1 - 0.0014 18.4 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family FaeA PF04703.12 ABK70253.1 - 0.0014 18.9 0.0 0.0024 18.2 0.0 1.4 1 0 0 1 1 1 1 FaeA-like protein HTH_DeoR PF08220.12 ABK70253.1 - 0.0074 16.0 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain DprA_WH PF17782.1 ABK70253.1 - 0.011 15.9 0.2 0.02 15.0 0.2 1.5 1 0 0 1 1 1 0 DprA winged helix domain HTH_Crp_2 PF13545.6 ABK70253.1 - 0.051 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain MarR PF01047.22 ABK70253.1 - 0.089 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 MarR family LexA_DNA_bind PF01726.16 ABK70253.1 - 0.11 12.3 0.1 0.25 11.1 0.1 1.6 1 1 0 1 1 1 0 LexA DNA binding domain HTH_47 PF16221.5 ABK70253.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 winged helix-turn-helix Methyltransf_11 PF08241.12 ABK70254.1 - 2.2e-23 82.7 0.0 3.9e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABK70254.1 - 3.5e-21 75.7 0.0 7.9e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABK70254.1 - 1.5e-18 67.0 0.0 2.2e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABK70254.1 - 2.3e-14 53.6 0.0 3.4e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK70254.1 - 2.1e-11 44.4 0.0 5.1e-11 43.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 ABK70254.1 - 5.7e-08 32.4 0.0 8.6e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 ABK70254.1 - 2e-07 30.0 0.0 2.4e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MetW PF07021.12 ABK70254.1 - 2e-05 24.3 0.0 3.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CMAS PF02353.20 ABK70254.1 - 2.8e-05 23.5 0.0 4.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Pox_MCEL PF03291.16 ABK70254.1 - 0.0014 17.8 0.0 0.043 12.9 0.0 2.1 2 0 0 2 2 2 1 mRNA capping enzyme MTS PF05175.14 ABK70254.1 - 0.0031 17.1 0.0 0.0059 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain DUF938 PF06080.12 ABK70254.1 - 0.0044 16.8 0.0 0.0093 15.8 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF938) TehB PF03848.14 ABK70254.1 - 0.0057 16.1 0.0 0.0084 15.5 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_4 PF02390.17 ABK70254.1 - 0.011 15.2 0.0 0.34 10.4 0.0 2.2 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_24 PF13578.6 ABK70254.1 - 0.024 15.6 0.0 0.05 14.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.15 ABK70254.1 - 0.067 13.0 0.0 0.11 12.3 0.0 1.5 1 1 0 1 1 1 0 Hypothetical methyltransferase UPF0225 PF17775.1 ABK70255.1 - 6.7e-27 94.2 0.0 8.1e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 UPF0225 domain SEC-C PF02810.15 ABK70255.1 - 1.3e-05 25.0 7.1 1.8e-05 24.6 7.1 1.2 1 0 0 1 1 1 1 SEC-C motif BPD_transp_2 PF02653.16 ABK70256.1 - 2e-39 135.4 29.0 2.9e-39 134.9 29.0 1.2 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component GET2 PF08690.10 ABK70256.1 - 0.15 11.7 0.3 0.23 11.1 0.3 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 RuBisCO_large PF00016.20 ABK70256.1 - 0.16 11.1 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Tcell_CD4_C PF12104.8 ABK70256.1 - 0.52 10.3 2.3 0.89 9.5 2.3 1.3 1 0 0 1 1 1 0 T cell CD4 receptor C terminal region DUF2537 PF10801.8 ABK70257.1 - 9.7e-31 105.8 23.1 1.1e-30 105.6 23.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2537) CoA_transf_3 PF02515.17 ABK70258.1 - 3.1e-32 112.1 4.1 4.1e-32 111.7 1.8 2.0 2 0 0 2 2 2 1 CoA-transferase family III Cupin_2 PF07883.11 ABK70259.1 - 3.7e-14 52.2 0.3 6.3e-14 51.4 0.3 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 ABK70259.1 - 0.00028 20.8 0.0 0.00044 20.2 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 ABK70259.1 - 0.073 12.7 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Cupin AMP-binding PF00501.28 ABK70260.1 - 1.9e-56 191.5 0.1 2.5e-56 191.1 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK70260.1 - 3.8e-09 37.4 0.0 1e-08 36.0 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FAD_binding_2 PF00890.24 ABK70261.1 - 7.5e-110 367.9 3.7 9.8e-110 367.5 3.7 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 ABK70261.1 - 3.9e-44 149.7 0.5 6.3e-44 149.1 0.5 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 ABK70261.1 - 9.7e-05 21.7 1.6 0.033 13.4 0.1 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ABK70261.1 - 0.00017 20.9 0.5 0.17 11.1 0.1 2.8 3 0 0 3 3 3 2 Thi4 family DAO PF01266.24 ABK70261.1 - 0.00049 19.8 0.9 0.0021 17.7 0.9 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ABK70261.1 - 0.0029 16.4 1.6 0.082 11.6 1.0 2.8 3 0 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.7 ABK70261.1 - 0.029 13.7 0.3 0.06 12.7 0.3 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 ABK70261.1 - 3.6 6.5 6.0 1.1 8.3 2.3 2.0 3 0 0 3 3 3 0 Glucose inhibited division protein A DDE_Tnp_ISL3 PF01610.17 ABK70262.1 - 1.6e-64 217.9 0.0 2.1e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Transposase zf-ISL3 PF14690.6 ABK70262.1 - 1.1e-09 38.8 4.6 1.8e-09 38.1 2.5 2.5 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HTH_Tnp_ISL3 PF13542.6 ABK70262.1 - 2.4e-08 33.2 1.6 7e-08 31.8 1.6 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 YhhN PF07947.14 ABK70263.1 - 2.3e-44 151.2 21.6 3.1e-44 150.8 21.6 1.2 1 0 0 1 1 1 1 YhhN family MTTB PF06253.11 ABK70263.1 - 0.2 9.6 3.1 0.32 8.9 3.1 1.3 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) Acetyltransf_3 PF13302.7 ABK70264.1 - 8.5e-27 94.5 0.0 1e-26 94.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ABK70264.1 - 3.5e-07 30.5 0.0 4.3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 ABK70264.1 - 0.0015 18.3 0.1 0.0022 17.7 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyco_transf_28 PF03033.20 ABK70265.1 - 5.7e-40 136.6 0.0 9.9e-40 135.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.16 ABK70265.1 - 2.8e-38 131.5 0.0 4e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_4 PF13439.6 ABK70265.1 - 8.9e-05 22.6 0.7 0.0022 18.0 0.3 2.4 2 1 0 2 2 2 1 Glycosyltransferase Family 4 CLP_protease PF00574.23 ABK70265.1 - 0.099 12.5 0.0 0.27 11.1 0.0 1.6 2 0 0 2 2 2 0 Clp protease PGA_cap PF09587.10 ABK70265.1 - 0.14 11.5 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap DUF63 PF01889.17 ABK70266.1 - 0.048 13.8 0.2 0.051 13.7 0.2 1.0 1 0 0 1 1 1 0 Membrane protein of unknown function DUF63 Gram_pos_anchor PF00746.21 ABK70266.1 - 0.11 12.5 1.3 0.11 12.5 1.3 2.8 3 0 0 3 3 3 0 LPXTG cell wall anchor motif DUF998 PF06197.13 ABK70266.1 - 0.19 11.3 9.8 0.64 9.6 9.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF998) DUF4225 PF13988.6 ABK70266.1 - 0.23 11.0 2.2 0.32 10.6 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4225) Epimerase PF01370.21 ABK70267.1 - 8.9e-38 130.1 0.0 1.2e-37 129.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ABK70267.1 - 4.1e-24 85.6 0.0 1.2e-23 84.0 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 ABK70267.1 - 8.9e-15 54.5 0.0 1.3e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 ABK70267.1 - 3.7e-08 32.7 0.0 5.1e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 ABK70267.1 - 0.00049 20.0 0.0 0.0015 18.5 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 ABK70267.1 - 0.0017 17.9 0.0 0.036 13.6 0.0 2.4 2 1 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.12 ABK70267.1 - 0.031 13.4 0.0 0.17 11.0 0.0 2.0 2 0 0 2 2 2 0 Male sterility protein Polysacc_synt_2 PF02719.15 ABK70267.1 - 0.086 12.0 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Latrotoxin_C PF15658.6 ABK70267.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Latrotoxin C-terminal domain Acyl-CoA_dh_1 PF00441.24 ABK70268.1 - 1.2e-15 58.0 4.7 2.6e-15 56.9 4.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 ABK70268.1 - 1.3e-06 28.7 7.9 7.4e-06 26.3 7.5 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AsnC_trans_reg PF01037.21 ABK70270.1 - 4.1e-17 61.9 0.6 7.9e-17 61.0 0.6 1.5 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_AsnC-type PF13404.6 ABK70270.1 - 5.2e-14 51.8 2.6 1e-13 50.9 2.6 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 ABK70270.1 - 1.7e-12 46.7 0.1 3.1e-12 45.8 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 ABK70270.1 - 4.1e-07 29.7 1.6 4.1e-07 29.7 1.6 1.8 2 0 0 2 2 2 1 IclR helix-turn-helix domain MarR_2 PF12802.7 ABK70270.1 - 1.7e-05 24.6 3.0 1.7e-05 24.6 1.2 1.9 2 0 0 2 2 2 1 MarR family HTH_20 PF12840.7 ABK70270.1 - 0.00026 21.0 2.0 0.00032 20.7 0.8 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain DprA_WH PF17782.1 ABK70270.1 - 0.00063 19.8 0.5 0.0014 18.7 0.5 1.6 1 0 0 1 1 1 1 DprA winged helix domain TrmB PF01978.19 ABK70270.1 - 0.001 18.9 0.0 0.022 14.7 0.0 2.3 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB NapD PF03927.13 ABK70270.1 - 0.0038 17.2 0.6 0.0076 16.3 0.6 1.4 1 0 0 1 1 1 1 NapD protein MarR PF01047.22 ABK70270.1 - 0.0078 16.1 0.2 0.026 14.4 0.0 1.8 2 0 0 2 2 2 1 MarR family HTH_5 PF01022.20 ABK70270.1 - 0.0084 16.0 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_Crp_2 PF13545.6 ABK70270.1 - 0.013 15.5 0.3 0.044 13.8 0.1 2.0 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_11 PF08279.12 ABK70270.1 - 0.028 14.4 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 HTH domain HTH_30 PF13556.6 ABK70270.1 - 0.029 14.2 0.7 0.071 12.9 0.7 1.8 1 1 0 1 1 1 0 PucR C-terminal helix-turn-helix domain GntR PF00392.21 ABK70270.1 - 0.049 13.3 0.4 0.1 12.3 0.4 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family DUF1441 PF07278.11 ABK70270.1 - 0.16 11.9 0.2 0.46 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1441) Aminotran_3 PF00202.21 ABK70271.1 - 4.6e-111 371.4 0.0 5.5e-111 371.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 ABK70271.1 - 0.081 12.1 0.0 0.21 10.7 0.0 1.6 1 1 0 1 1 1 0 Aminotransferase class I and II Putative_PNPOx PF01243.20 ABK70272.1 - 1.4e-13 50.8 0.0 2e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase MFS_1 PF07690.16 ABK70273.1 - 6.8e-41 140.4 56.5 6.8e-41 140.4 56.5 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 ABK70273.1 - 0.086 11.1 0.5 0.18 10.0 0.5 1.5 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 ABK70273.1 - 0.18 10.3 43.6 0.032 12.8 3.1 3.5 3 1 0 3 3 3 0 MFS/sugar transport protein DUF4129 PF13559.6 ABK70273.1 - 5 7.5 11.0 0.16 12.3 3.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) Phage_holin_3_6 PF07332.11 ABK70274.1 - 0.02 14.9 10.5 0.021 14.9 10.5 1.0 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III EI24 PF07264.11 ABK70274.1 - 0.13 12.5 6.8 0.13 12.5 6.8 1.0 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) PhoR PF11808.8 ABK70274.1 - 3 8.3 11.2 4 7.9 11.2 1.2 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR Band_7 PF01145.25 ABK70275.1 - 1.1e-30 107.0 3.5 1.1e-30 107.0 3.5 2.0 1 1 1 2 2 2 1 SPFH domain / Band 7 family Asp_Glu_race PF01177.22 ABK70275.1 - 0.037 13.9 1.5 0.072 12.9 0.3 2.0 2 1 1 3 3 3 0 Asp/Glu/Hydantoin racemase Ntox1 PF15500.6 ABK70275.1 - 0.4 11.0 2.7 1.8 9.0 2.7 2.2 1 1 0 1 1 1 0 Putative RNase-like toxin, toxin_1 OppC_N PF12911.7 ABK70275.1 - 0.73 9.9 3.6 1.6 8.8 3.6 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF1989 PF09347.10 ABK70276.1 - 2e-60 203.2 0.0 2.4e-60 203.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) MlaD PF02470.20 ABK70277.1 - 1.7e-18 66.7 0.5 3.3e-18 65.7 0.5 1.5 1 0 0 1 1 1 1 MlaD protein Mce4_CUP1 PF11887.8 ABK70277.1 - 8.4e-06 25.4 2.7 4.3e-05 23.1 2.7 1.9 1 1 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative DASH_Dam1 PF08653.10 ABK70277.1 - 0.011 15.5 1.2 0.59 10.0 0.2 3.0 2 1 1 3 3 3 0 DASH complex subunit Dam1 NPV_P10 PF05531.12 ABK70277.1 - 0.017 15.6 3.9 0.057 13.9 0.3 2.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein PLAC9 PF15205.6 ABK70277.1 - 0.023 15.1 0.1 0.36 11.2 0.0 2.7 3 0 0 3 3 3 0 Placenta-specific protein 9 RPW8 PF05659.11 ABK70277.1 - 0.038 13.7 0.2 0.1 12.3 0.0 1.7 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 TMF_TATA_bd PF12325.8 ABK70277.1 - 0.046 14.0 1.0 3.8 7.8 0.1 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding FATC PF02260.20 ABK70277.1 - 0.063 13.1 0.1 6.9 6.6 0.0 2.4 2 0 0 2 2 2 0 FATC domain COG5 PF10392.9 ABK70277.1 - 0.12 12.6 4.0 5 7.3 0.1 2.3 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Tweety PF04906.13 ABK70277.1 - 0.19 10.4 1.0 0.5 9.0 0.8 1.8 1 1 0 1 1 1 0 Tweety DUF948 PF06103.11 ABK70277.1 - 0.22 11.8 7.1 1.2 9.5 0.6 3.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) CENP-Q PF13094.6 ABK70277.1 - 0.32 11.2 4.8 0.62 10.2 4.8 1.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Baculo_PEP_C PF04513.12 ABK70277.1 - 0.75 9.8 13.0 5.7 7.0 4.3 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG17 PF04108.12 ABK70277.1 - 1.1 8.3 4.5 3.7 6.6 0.2 2.1 1 1 0 2 2 2 0 Autophagy protein Apg17 Dehydratase_SU PF02287.15 ABK70278.1 - 5.1e-33 114.0 0.5 5.6e-33 113.8 0.5 1.0 1 0 0 1 1 1 1 Dehydratase small subunit EspB_PE PF18625.1 ABK70278.1 - 2.3 8.8 9.7 2.8 8.5 7.1 2.2 1 1 1 2 2 2 0 ESX-1 secreted protein B PE domain SnoaL_2 PF12680.7 ABK70279.1 - 3e-10 40.6 0.3 3.9e-10 40.3 0.3 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 ABK70279.1 - 4.1e-07 29.9 0.1 6.3e-07 29.2 0.1 1.4 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DUF4440 PF14534.6 ABK70279.1 - 0.067 13.6 0.0 0.093 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) p450 PF00067.22 ABK70280.1 - 1.2e-54 185.9 0.0 2.1e-54 185.0 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Inositol_P PF00459.25 ABK70281.1 - 1.5e-49 168.9 0.0 1.8e-49 168.7 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family adh_short_C2 PF13561.6 ABK70282.1 - 1.1e-57 195.2 4.1 1.5e-57 194.9 4.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK70282.1 - 1e-49 168.7 2.0 1.2e-49 168.5 2.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK70282.1 - 1.4e-05 25.1 3.3 2.6e-05 24.2 2.9 1.7 1 1 1 2 2 2 1 KR domain 3HCDH_N PF02737.18 ABK70282.1 - 0.00041 20.3 1.4 0.00073 19.5 0.3 2.0 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 ABK70282.1 - 0.0025 17.3 0.6 0.0032 17.0 0.1 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ABK70282.1 - 0.004 16.3 0.4 0.0055 15.8 0.4 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain LytR_C PF13399.6 ABK70282.1 - 0.0073 17.3 1.1 0.042 14.8 0.3 2.4 2 1 0 2 2 2 1 LytR cell envelope-related transcriptional attenuator Sacchrp_dh_NADP PF03435.18 ABK70282.1 - 0.0075 16.5 0.3 0.019 15.2 0.3 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain UPF0146 PF03686.13 ABK70282.1 - 0.048 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) CbiA PF01656.23 ABK70282.1 - 0.071 13.2 0.0 0.14 12.2 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain HHH_5 PF14520.6 ABK70282.1 - 0.088 13.4 1.2 0.56 10.9 0.1 2.7 3 0 0 3 3 3 0 Helix-hairpin-helix domain NmrA PF05368.13 ABK70282.1 - 0.09 12.3 0.8 0.29 10.7 0.6 1.8 2 1 0 2 2 2 0 NmrA-like family Pyr_redox_2 PF07992.14 ABK70283.1 - 7.8e-56 189.4 5.2 9.8e-56 189.1 5.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ABK70283.1 - 5.2e-27 94.3 0.1 2.1e-24 85.9 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 ABK70283.1 - 2.9e-24 85.4 4.3 5.1e-19 68.6 0.4 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ABK70283.1 - 1e-11 44.9 4.6 5e-11 42.6 0.4 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ABK70283.1 - 1.4e-10 41.0 5.2 1.2e-06 28.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ABK70283.1 - 2.5e-10 40.0 1.2 1.4e-05 24.4 0.3 3.0 3 0 0 3 3 3 2 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 ABK70283.1 - 5e-08 32.5 2.6 8.8e-05 21.9 0.2 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 ABK70283.1 - 1.5e-07 31.6 2.3 0.0012 19.0 0.3 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ABK70283.1 - 1e-06 27.7 9.0 0.0014 17.4 2.0 3.3 2 1 1 3 3 3 3 HI0933-like protein FAD_binding_2 PF00890.24 ABK70283.1 - 2.6e-06 26.8 13.2 1.4e-05 24.3 4.4 3.1 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 ABK70283.1 - 6e-06 26.1 10.6 0.058 13.0 0.1 3.4 3 1 0 3 3 3 3 FAD dependent oxidoreductase 3HCDH_N PF02737.18 ABK70283.1 - 7e-05 22.8 3.7 0.00044 20.2 0.1 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 ABK70283.1 - 7.3e-05 23.3 0.3 0.043 14.3 0.1 2.5 2 0 0 2 2 2 1 XdhC Rossmann domain FAD_binding_3 PF01494.19 ABK70283.1 - 0.00053 19.3 3.8 0.39 9.9 0.2 2.5 2 1 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 ABK70283.1 - 0.0018 17.5 6.2 0.036 13.3 1.5 2.5 2 1 0 2 2 2 2 Thi4 family K_oxygenase PF13434.6 ABK70283.1 - 0.0041 16.3 0.1 0.026 13.7 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.18 ABK70283.1 - 0.015 15.6 0.6 0.096 13.0 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 ABK70283.1 - 0.025 13.9 3.0 0.069 12.5 0.0 2.6 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.21 ABK70283.1 - 0.027 13.9 0.1 0.049 13.0 0.1 1.3 1 0 0 1 1 1 0 ThiF family NAD_binding_7 PF13241.6 ABK70283.1 - 0.03 14.8 0.9 0.33 11.4 0.1 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 ABK70283.1 - 0.04 13.5 0.6 0.04 13.5 0.6 2.6 2 2 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.12 ABK70283.1 - 1.5 7.8 6.2 13 4.7 1.5 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein ECH_1 PF00378.20 ABK70284.1 - 3e-44 151.2 0.6 3.5e-44 151.0 0.6 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK70284.1 - 7.8e-28 97.9 0.4 8.7e-28 97.8 0.4 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase His_Phos_1 PF00300.22 ABK70285.1 - 1.4e-23 83.6 0.9 1.7e-23 83.4 0.9 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Histidinol_dh PF00815.20 ABK70286.1 - 7.3e-139 463.3 0.4 8.5e-139 463.1 0.4 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase TipAS PF07739.13 ABK70286.1 - 0.087 13.4 0.0 0.25 11.9 0.0 1.7 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain p450 PF00067.22 ABK70288.1 - 2.1e-18 66.3 0.0 1e-15 57.5 0.0 3.1 1 1 0 1 1 1 1 Cytochrome P450 4HBT_3 PF13622.6 ABK70289.1 - 3.7e-41 142.0 3.3 4.4e-41 141.8 3.3 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4129 PF13559.6 ABK70290.1 - 1.4e-10 41.2 5.3 6.1e-10 39.2 5.3 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) SLAC1 PF03595.17 ABK70290.1 - 0.012 14.9 0.6 0.067 12.4 0.2 1.9 2 0 0 2 2 2 0 Voltage-dependent anion channel DUF3549 PF12069.8 ABK70290.1 - 0.15 11.1 0.6 0.19 10.7 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) EphA2_TM PF14575.6 ABK70290.1 - 0.58 11.1 2.3 5.7 7.9 0.0 3.0 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF5134 PF17197.4 ABK70290.1 - 2.9 7.8 13.7 1.8 8.5 2.9 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF5134) DUF4131 PF13567.6 ABK70290.1 - 8.9 5.9 10.9 11 5.6 4.7 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) ECH_1 PF00378.20 ABK70291.1 - 3.1e-56 190.5 0.1 3.5e-56 190.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK70291.1 - 9.1e-33 114.1 1.5 2.3e-31 109.5 0.6 1.9 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase SBD_N PF07005.11 ABK70292.1 - 7.5e-49 166.5 5.7 1.1e-48 166.0 5.7 1.2 1 0 0 1 1 1 1 Sugar-binding N-terminal domain NBD_C PF17042.5 ABK70292.1 - 1.1e-20 74.8 0.7 1.1e-20 74.8 0.7 2.4 3 0 0 3 3 3 1 Nucleotide-binding C-terminal domain Toprim_3 PF13362.6 ABK70292.1 - 3.3 8.1 5.9 8.4 6.8 0.1 3.6 4 1 0 4 4 4 0 Toprim domain AAA_5 PF07728.14 ABK70293.1 - 1.1e-13 51.4 0.0 2e-13 50.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 ABK70293.1 - 6.5e-10 39.0 0.0 0.0004 20.3 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 ABK70293.1 - 8.1e-10 39.2 0.0 3.3e-09 37.2 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ABK70293.1 - 6.1e-06 26.6 0.0 1.4e-05 25.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ABK70293.1 - 6.8e-06 26.6 1.0 3.5e-05 24.2 1.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 ABK70293.1 - 0.0033 17.6 0.0 0.0057 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) NACHT PF05729.12 ABK70293.1 - 0.0035 17.3 0.4 0.034 14.1 0.0 2.2 2 1 0 2 2 2 1 NACHT domain Mg_chelatase PF01078.21 ABK70293.1 - 0.0037 16.7 0.0 0.0058 16.0 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 ABK70293.1 - 0.0069 16.1 0.2 0.19 11.5 0.1 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 ABK70293.1 - 0.014 15.5 0.3 0.037 14.2 0.1 1.8 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ABK70293.1 - 0.016 14.8 0.7 0.68 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 ABK70293.1 - 0.018 14.8 0.0 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.6 ABK70293.1 - 0.021 15.4 0.0 0.033 14.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 ABK70293.1 - 0.025 14.6 0.1 0.077 13.0 0.1 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 ABK70293.1 - 0.05 14.0 0.0 0.12 12.8 0.0 1.7 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 ABK70293.1 - 0.056 13.2 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 ABK70293.1 - 0.056 13.8 0.3 2.1 8.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 ABK70293.1 - 0.079 12.7 0.4 0.2 11.3 0.4 1.8 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 ABK70293.1 - 0.094 12.6 0.1 0.25 11.2 0.1 2.0 1 1 0 1 1 1 0 NTPase AAA_6 PF12774.7 ABK70293.1 - 0.1 11.6 0.1 0.15 11.0 0.1 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region BTG PF07742.12 ABK70293.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 BTG family Rad17 PF03215.15 ABK70293.1 - 0.19 11.7 0.0 0.46 10.4 0.1 1.6 2 0 0 2 2 2 0 Rad17 P-loop domain HTH_20 PF12840.7 ABK70294.1 - 1.4e-09 37.9 0.2 2.6e-09 37.0 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 ABK70294.1 - 1.5e-06 28.0 0.5 2.5e-06 27.3 0.5 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family Rrf2 PF02082.20 ABK70294.1 - 0.0084 16.4 0.1 0.015 15.6 0.1 1.5 1 1 0 1 1 1 1 Transcriptional regulator MarR_2 PF12802.7 ABK70294.1 - 0.043 13.7 0.2 0.081 12.8 0.2 1.4 1 0 0 1 1 1 0 MarR family E3_UFM1_ligase PF09743.9 ABK70294.1 - 0.079 12.6 0.0 0.097 12.3 0.0 1.1 1 0 0 1 1 1 0 E3 UFM1-protein ligase 1 GntR PF00392.21 ABK70295.1 - 1.2e-14 53.6 0.2 1.8e-14 53.1 0.2 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 ABK70295.1 - 7.5e-07 28.6 0.1 3.1e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_41 PF14502.6 ABK70295.1 - 1.2e-06 28.1 0.0 2.1e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AsnC-type PF13404.6 ABK70295.1 - 5.8e-05 22.8 1.3 0.027 14.3 0.1 2.4 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain HTH_Crp_2 PF13545.6 ABK70295.1 - 6.1e-05 22.9 0.1 0.00015 21.7 0.0 1.7 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_36 PF13730.6 ABK70295.1 - 0.0001 22.2 0.0 0.0031 17.4 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 ABK70295.1 - 0.00016 21.5 1.5 0.005 16.7 0.2 2.2 2 0 0 2 2 2 1 MarR family HTH_28 PF13518.6 ABK70295.1 - 0.0015 18.7 0.8 0.42 10.8 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_IclR PF09339.10 ABK70295.1 - 0.0024 17.6 2.3 0.021 14.6 0.4 2.1 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_CodY PF08222.11 ABK70295.1 - 0.0036 16.8 0.2 0.036 13.6 0.0 2.1 2 0 0 2 2 2 1 CodY helix-turn-helix domain HTH_29 PF13551.6 ABK70295.1 - 0.004 17.1 0.4 0.91 9.6 0.1 2.3 2 0 0 2 2 2 1 Winged helix-turn helix HTH_20 PF12840.7 ABK70295.1 - 0.0054 16.8 0.4 0.04 14.0 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_8 PF02954.19 ABK70295.1 - 0.012 15.3 0.3 0.032 14.0 0.3 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family HTH_Tnp_ISL3 PF13542.6 ABK70295.1 - 0.02 14.3 0.6 2.7 7.5 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 LexA_DNA_bind PF01726.16 ABK70295.1 - 0.021 14.6 0.1 0.055 13.3 0.0 1.7 2 0 0 2 2 2 0 LexA DNA binding domain NUMOD1 PF07453.13 ABK70295.1 - 0.029 14.6 0.0 1 9.7 0.0 2.2 2 0 0 2 2 2 0 NUMOD1 domain Rrf2 PF02082.20 ABK70295.1 - 0.083 13.3 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator HTH_17 PF12728.7 ABK70295.1 - 0.11 12.8 0.1 2.9 8.1 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 ABK70295.1 - 0.11 12.3 0.3 13 5.7 0.0 2.4 3 0 0 3 3 2 0 Homeodomain-like domain HTH_5 PF01022.20 ABK70295.1 - 0.14 12.1 0.0 0.43 10.5 0.0 1.9 1 1 0 1 1 1 0 Bacterial regulatory protein, arsR family Glyoxalase_4 PF13669.6 ABK70296.1 - 1.4e-29 102.6 0.1 2.4e-29 101.8 0.1 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 ABK70296.1 - 0.038 14.1 0.2 0.081 13.0 0.2 1.7 1 1 0 1 1 1 0 Glyoxalase-like domain DeoRC PF00455.22 ABK70297.1 - 2.3e-49 167.4 1.0 2.9e-49 167.1 1.0 1.1 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 ABK70297.1 - 1e-12 47.6 0.1 2.4e-12 46.4 0.0 1.7 2 0 0 2 2 1 1 DeoR-like helix-turn-helix domain GntR PF00392.21 ABK70297.1 - 1.7e-05 24.4 0.5 5.2e-05 22.8 0.5 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_11 PF08279.12 ABK70297.1 - 0.00015 21.6 0.1 0.00052 19.9 0.0 1.9 2 0 0 2 2 2 1 HTH domain Put_DNA-bind_N PF06971.13 ABK70297.1 - 0.00064 19.7 0.0 0.0019 18.2 0.0 1.8 1 0 0 1 1 1 1 Putative DNA-binding protein N-terminus HTH_Crp_2 PF13545.6 ABK70297.1 - 0.0019 18.2 0.7 0.03 14.3 0.0 2.5 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain DprA_WH PF17782.1 ABK70297.1 - 0.0033 17.5 0.3 0.014 15.5 0.3 2.1 1 0 0 1 1 1 1 DprA winged helix domain Rrf2 PF02082.20 ABK70297.1 - 0.0056 17.0 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulator DUF2250 PF10007.9 ABK70297.1 - 0.014 15.5 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) FeoC PF09012.10 ABK70297.1 - 0.018 15.1 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 FeoC like transcriptional regulator MarR PF01047.22 ABK70297.1 - 0.025 14.5 0.0 0.066 13.2 0.0 1.7 1 0 0 1 1 1 0 MarR family FaeA PF04703.12 ABK70297.1 - 0.037 14.4 0.0 0.11 12.9 0.0 1.9 1 0 0 1 1 1 0 FaeA-like protein HTH_29 PF13551.6 ABK70297.1 - 0.051 13.6 0.5 2.9 8.0 0.0 2.5 2 1 0 2 2 2 0 Winged helix-turn helix PAX PF00292.18 ABK70297.1 - 0.095 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 'Paired box' domain MarR_2 PF12802.7 ABK70297.1 - 0.19 11.7 2.8 1 9.3 1.1 2.4 2 0 0 2 2 2 0 MarR family HTH_20 PF12840.7 ABK70297.1 - 3.4 7.8 8.3 0.37 10.9 2.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain MerR_1 PF13411.6 ABK70298.1 - 1.6e-17 63.4 0.0 2.7e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 ABK70298.1 - 7.2e-12 44.9 0.2 1.4e-11 44.0 0.2 1.5 1 0 0 1 1 1 1 MerR family regulatory protein MerR_2 PF13591.6 ABK70298.1 - 4.9e-09 35.9 0.2 6.2e-09 35.6 0.2 1.2 1 0 0 1 1 1 1 MerR HTH family regulatory protein DivIC PF04977.15 ABK70298.1 - 0.00086 19.0 1.1 0.0049 16.6 0.1 2.1 2 0 0 2 2 2 1 Septum formation initiator DUF1192 PF06698.11 ABK70298.1 - 0.0057 16.7 0.7 0.018 15.1 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) TolA_bind_tri PF16331.5 ABK70298.1 - 0.015 15.4 1.5 0.039 14.0 1.4 1.7 1 1 1 2 2 2 0 TolA binding protein trimerisation LPP PF04728.13 ABK70298.1 - 0.032 14.6 0.1 0.12 12.8 0.0 1.9 2 0 0 2 2 2 0 Lipoprotein leucine-zipper WD40_alt PF14077.6 ABK70298.1 - 0.032 14.1 0.1 0.074 12.9 0.1 1.6 1 0 0 1 1 1 0 Alternative WD40 repeat motif CLZ PF16526.5 ABK70298.1 - 0.065 13.6 0.3 0.11 12.8 0.3 1.5 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MbeD_MobD PF04899.12 ABK70298.1 - 0.083 13.0 1.7 0.58 10.3 1.6 2.0 1 1 1 2 2 2 0 MbeD/MobD like bZIP_2 PF07716.15 ABK70298.1 - 0.087 12.9 1.7 0.19 11.8 0.3 2.2 2 0 0 2 2 2 0 Basic region leucine zipper TMF_DNA_bd PF12329.8 ABK70298.1 - 0.17 11.9 0.4 0.5 10.4 0.4 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DNA_pol3_beta PF00712.19 ABK70300.1 - 4.2e-48 162.5 0.0 6.3e-39 132.8 0.0 2.8 3 0 0 3 3 3 2 DNA polymerase III beta subunit, N-terminal domain DNA_pol3_beta_2 PF02767.16 ABK70300.1 - 2.2e-39 134.3 0.0 1.6e-35 121.8 0.0 2.5 3 0 0 3 3 3 2 DNA polymerase III beta subunit, central domain DNA_pol3_beta_3 PF02768.15 ABK70300.1 - 3e-36 123.9 0.0 5e-35 120.0 0.0 2.4 2 0 0 2 2 2 1 DNA polymerase III beta subunit, C-terminal domain SEF14_adhesin PF06443.11 ABK70300.1 - 0.02 14.7 0.1 0.059 13.2 0.0 1.8 2 0 0 2 2 2 0 SEF14-like adhesin Glyoxalase PF00903.25 ABK70301.1 - 3.1e-10 40.3 0.0 4e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ABK70301.1 - 1.3e-09 38.7 0.0 2e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Methyltransf_25 PF13649.6 ABK70302.1 - 6.5e-20 71.6 0.1 1.1e-19 70.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABK70302.1 - 9.1e-18 64.7 0.1 1.6e-17 63.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABK70302.1 - 1.8e-15 57.1 0.1 2.9e-15 56.4 0.1 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK70302.1 - 2.7e-11 44.1 0.1 3.8e-11 43.6 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 ABK70302.1 - 4.5e-11 42.8 0.0 1e-10 41.6 0.0 1.5 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 ABK70302.1 - 7.3e-11 42.2 0.0 8.6e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ABK70302.1 - 4.4e-08 32.8 0.0 6.1e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 ABK70302.1 - 1.1e-07 31.5 0.0 1.5e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 ABK70302.1 - 3.1e-07 30.1 0.0 4e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 ABK70302.1 - 5.4e-06 25.9 0.0 6.9e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB CMAS PF02353.20 ABK70302.1 - 1.9e-05 24.1 0.0 2.5e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_15 PF09445.10 ABK70302.1 - 7.9e-05 22.3 0.0 9.5e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase NodS PF05401.11 ABK70302.1 - 0.00026 20.6 0.0 0.00035 20.3 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) PCMT PF01135.19 ABK70302.1 - 0.0012 18.6 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 ABK70302.1 - 0.0036 16.9 0.1 0.0094 15.6 0.1 1.6 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 ABK70302.1 - 0.008 16.2 0.0 0.012 15.6 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 ABK70302.1 - 0.033 14.5 0.0 1.7 9.0 0.0 2.3 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase Methyltransf_18 PF12847.7 ABK70302.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 ABK70302.1 - 0.17 11.6 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 TetR_N PF00440.23 ABK70303.1 - 8.7e-16 57.4 0.0 1.9e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 ABK70303.1 - 2.5e-09 37.4 3.4 3.8e-09 36.8 3.4 1.3 1 0 0 1 1 1 1 BetI-type transcriptional repressor, C-terminal TetR_C_29 PF17938.1 ABK70303.1 - 6.5e-05 23.0 0.0 0.00011 22.3 0.0 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_36 PF18598.1 ABK70303.1 - 0.00014 21.8 0.3 0.00021 21.2 0.3 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_11 PF16859.5 ABK70303.1 - 0.00022 21.5 6.2 0.00043 20.6 6.0 1.7 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_31 PF17940.1 ABK70303.1 - 0.0023 18.1 4.5 0.24 11.6 6.2 2.4 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_21 PF17926.1 ABK70303.1 - 0.0031 17.6 0.1 0.0062 16.7 0.1 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_33 PF13305.6 ABK70303.1 - 0.035 14.8 4.3 0.041 14.6 3.0 1.8 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HAD_2 PF13419.6 ABK70303.1 - 0.097 12.7 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase TetR_C_15 PF17918.1 ABK70303.1 - 0.19 12.5 4.2 4.9 7.9 4.5 2.4 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain UDPG_MGDP_dh_N PF03721.14 ABK70304.1 - 7.6e-53 178.9 0.0 1.1e-52 178.4 0.0 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 ABK70304.1 - 1.8e-27 95.4 0.0 3e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 ABK70304.1 - 5.4e-14 52.5 0.0 4.2e-13 49.6 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.15 ABK70304.1 - 1.8e-05 25.0 0.1 0.00018 21.8 0.1 2.2 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 ABK70304.1 - 0.0003 20.4 0.1 0.0005 19.7 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 ABK70304.1 - 0.0023 17.8 0.3 0.0042 17.0 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 ABK70304.1 - 0.014 15.9 0.9 0.34 11.5 0.3 2.9 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 ABK70304.1 - 0.039 13.9 0.1 0.095 12.7 0.1 1.7 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.19 ABK70304.1 - 0.042 13.2 0.1 0.094 12.1 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 ABK70304.1 - 0.056 12.9 0.1 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family AlaDh_PNT_C PF01262.21 ABK70304.1 - 0.068 12.5 0.3 0.15 11.3 0.3 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 ABK70304.1 - 0.092 13.0 0.1 0.22 11.8 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_11 PF14833.6 ABK70304.1 - 0.12 12.7 0.0 1.1 9.5 0.0 2.3 1 1 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase CUE PF02845.16 ABK70304.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 CUE domain ECH_1 PF00378.20 ABK70305.1 - 6.7e-43 146.8 0.0 8.9e-43 146.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK70305.1 - 5.2e-31 108.4 0.0 5.8e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase BPL_LplA_LipB PF03099.19 ABK70306.1 - 8.6e-10 38.6 0.0 1.2e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Gp_dh_C PF02800.20 ABK70306.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.4 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Esterase PF00756.20 ABK70307.1 - 5.2e-06 26.3 0.4 4.1e-05 23.4 0.4 2.1 1 1 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 ABK70307.1 - 0.029 13.6 0.2 0.055 12.7 0.2 1.4 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ABK70307.1 - 0.07 12.8 0.3 0.098 12.3 0.3 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Asp2 PF16929.5 ABK70307.1 - 0.078 11.9 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter BAAT_C PF08840.11 ABK70307.1 - 0.2 11.5 0.0 0.3 11.0 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 ABK70307.1 - 0.22 11.0 0.3 0.45 10.0 0.3 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family cobW PF02492.19 ABK70308.1 - 1.7e-35 122.2 0.0 2.1e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 ABK70308.1 - 1.5e-05 24.2 0.8 0.077 12.0 0.2 2.1 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 ABK70308.1 - 0.003 18.0 0.0 0.004 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 ABK70308.1 - 0.003 18.1 0.0 0.0047 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 ABK70308.1 - 0.02 14.2 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF463 PF04317.12 ABK70308.1 - 0.027 13.4 0.0 0.034 13.1 0.0 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 MMR_HSR1 PF01926.23 ABK70308.1 - 0.051 13.7 0.0 0.11 12.5 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.14 ABK70308.1 - 0.061 13.3 0.0 0.097 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 ABK70308.1 - 0.079 13.1 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ABK70308.1 - 0.08 13.5 0.0 0.1 13.1 0.0 1.3 1 0 0 1 1 1 0 ABC transporter MobB PF03205.14 ABK70308.1 - 0.1 12.5 0.0 4.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 ABK70308.1 - 0.1 13.0 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 ABK70308.1 - 0.17 11.0 0.0 0.26 10.5 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 ABK70308.1 - 0.19 12.1 0.0 0.36 11.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NLPC_P60 PF00877.19 ABK70310.1 - 6.8e-31 106.4 0.0 1.4e-30 105.4 0.0 1.6 1 0 0 1 1 1 1 NlpC/P60 family Spc7 PF08317.11 ABK70310.1 - 0.31 9.9 15.0 0.56 9.0 0.9 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF1569 PF07606.11 ABK70310.1 - 0.35 10.9 2.6 0.63 10.0 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1569) DUF16 PF01519.16 ABK70310.1 - 0.57 10.7 6.2 0.53 10.8 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 RF-1 PF00472.20 ABK70310.1 - 3.1 7.8 11.5 0.28 11.1 6.6 1.7 2 0 0 2 2 2 0 RF-1 domain FliJ PF02050.16 ABK70310.1 - 4.2 7.6 28.9 0.045 14.0 3.2 3.2 2 1 1 3 3 3 0 Flagellar FliJ protein Seryl_tRNA_N PF02403.22 ABK70310.1 - 5.2 7.3 12.4 9.9 6.5 2.5 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 ABK70310.1 - 5.5 7.5 17.1 7.1 7.2 1.1 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region RNA_pol_Rpb2_6 PF00562.28 ABK70312.1 - 5.3e-159 529.5 0.0 2.1e-158 527.5 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.16 ABK70312.1 - 1.7e-29 101.8 0.0 3.8e-29 100.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_45 PF10385.9 ABK70312.1 - 2.4e-29 101.4 2.7 2.9e-28 97.9 3.5 2.4 2 0 0 2 2 2 1 RNA polymerase beta subunit external 1 domain RNA_pol_Rpb2_7 PF04560.20 ABK70312.1 - 3.2e-26 91.5 0.0 6.7e-26 90.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 ABK70312.1 - 4.6e-26 91.6 0.0 1.2e-25 90.3 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_1 PF04563.15 ABK70312.1 - 1.3e-22 80.3 0.0 3.8e-22 78.8 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase beta subunit Peptidase_M23 PF01551.22 ABK70312.1 - 0.15 12.3 1.0 0.78 10.0 0.1 2.6 3 0 0 3 3 3 0 Peptidase family M23 Aldedh PF00171.22 ABK70313.1 - 3.9e-142 474.0 0.0 4.8e-142 473.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 ABK70313.1 - 0.00063 18.9 0.0 0.0016 17.6 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Flavin_Reduct PF01613.18 ABK70314.1 - 2.1e-34 118.8 0.0 2.3e-34 118.7 0.0 1.0 1 0 0 1 1 1 1 Flavin reductase like domain HATPase_c PF02518.26 ABK70315.1 - 3.4e-17 63.0 0.0 7.1e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase sCache_3_2 PF17203.4 ABK70315.1 - 1.4e-14 54.4 5.0 1.5e-14 54.3 0.3 2.8 3 0 0 3 3 3 1 Single cache domain 3 SPOB_a PF14689.6 ABK70315.1 - 9e-12 44.5 0.0 1.5e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Sensor_kinase_SpoOB-type, alpha-helical domain PAS PF00989.25 ABK70315.1 - 4.9e-07 29.7 0.0 2.3e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 PAS fold HATPase_c_5 PF14501.6 ABK70315.1 - 1.5e-05 24.8 0.0 2.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 GHKL domain PAS_8 PF13188.7 ABK70315.1 - 0.00016 21.6 0.0 0.00057 19.8 0.0 1.9 1 0 0 1 1 1 1 PAS domain LapA_dom PF06305.11 ABK70315.1 - 0.024 14.5 2.0 0.65 9.9 0.3 2.7 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain PAS_9 PF13426.7 ABK70315.1 - 0.024 14.9 0.0 0.045 14.0 0.0 1.6 1 0 0 1 1 1 0 PAS domain PAS_4 PF08448.10 ABK70315.1 - 0.035 14.3 0.5 0.74 10.1 0.1 3.1 2 1 0 2 2 2 0 PAS fold PAS_7 PF12860.7 ABK70315.1 - 0.037 14.2 0.0 0.13 12.4 0.0 2.1 1 1 0 1 1 1 0 PAS fold TolA_bind_tri PF16331.5 ABK70315.1 - 0.16 12.0 0.2 0.37 10.9 0.2 1.6 1 0 0 1 1 1 0 TolA binding protein trimerisation Amidohydro_2 PF04909.14 ABK70316.1 - 1.4e-21 77.6 2.3 2.2e-21 76.9 2.3 1.4 1 0 0 1 1 1 1 Amidohydrolase Peptidase_M19 PF01244.21 ABK70316.1 - 0.085 12.0 0.0 0.21 10.7 0.0 1.6 2 0 0 2 2 2 0 Membrane dipeptidase (Peptidase family M19) DinB_2 PF12867.7 ABK70317.1 - 2.4e-19 70.1 8.9 1.2e-18 67.9 8.9 1.9 1 1 0 1 1 1 1 DinB superfamily DUF664 PF04978.12 ABK70317.1 - 0.0015 18.9 0.4 0.042 14.3 0.4 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF664) Aminotran_1_2 PF00155.21 ABK70318.1 - 1.5e-46 159.3 0.0 1.8e-46 159.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 ABK70318.1 - 8.7e-05 21.2 0.0 0.00015 20.4 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 ABK70318.1 - 0.0008 18.8 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.13 ABK70318.1 - 0.026 13.4 0.0 0.047 12.5 0.0 1.6 1 1 0 1 1 1 0 Allinase Abhydrolase_6 PF12697.7 ABK70319.1 - 2.5e-18 67.5 17.7 2.9e-18 67.3 17.7 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ABK70319.1 - 1.2e-09 38.2 1.2 5.9e-07 29.4 0.3 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ABK70319.1 - 1.1e-08 34.7 0.1 2.9e-08 33.3 0.1 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 ABK70319.1 - 0.02 14.5 0.0 0.041 13.5 0.0 1.5 1 1 0 1 1 1 0 Putative esterase Ser_hydrolase PF06821.13 ABK70319.1 - 0.02 14.7 0.4 0.042 13.7 0.1 1.8 2 0 0 2 2 2 0 Serine hydrolase Peptidase_S10 PF00450.22 ABK70319.1 - 0.04 13.3 0.1 0.051 13.0 0.1 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase PhyH PF05721.13 ABK70320.1 - 1.2e-32 113.9 0.0 1.6e-32 113.5 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AbiEi_1 PF09407.10 ABK70320.1 - 0.32 11.3 1.8 6 7.2 0.0 3.2 4 0 0 4 4 4 0 AbiEi antitoxin C-terminal domain META PF03724.16 ABK70321.1 - 2.8e-52 175.3 0.2 3.4e-27 94.5 0.1 2.1 2 0 0 2 2 2 2 META domain Big_9 PF17963.1 ABK70321.1 - 2.5 8.9 8.4 21 5.9 0.2 2.5 2 0 0 2 2 2 0 Bacterial Ig domain Mal_decarbox_Al PF16957.5 ABK70322.1 - 1.9e-92 310.4 0.0 2.1e-92 310.2 0.0 1.0 1 0 0 1 1 1 1 Malonate decarboxylase, alpha subunit, transporter AcetylCoA_hyd_C PF13336.6 ABK70322.1 - 0.19 11.6 0.1 0.39 10.7 0.0 1.7 2 0 0 2 2 2 0 Acetyl-CoA hydrolase/transferase C-terminal domain HxlR PF01638.17 ABK70323.1 - 2.6e-25 88.1 0.0 3.2e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix MarR PF01047.22 ABK70323.1 - 0.00068 19.5 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 MarR family PadR PF03551.14 ABK70323.1 - 0.013 15.5 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Aldolase PF01081.19 ABK70324.1 - 4.1e-45 153.6 0.2 5e-45 153.3 0.2 1.0 1 0 0 1 1 1 1 KDPG and KHG aldolase DMRL_synthase PF00885.19 ABK70324.1 - 0.0037 17.1 0.3 0.0094 15.8 0.3 1.6 1 1 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase SUFU PF05076.13 ABK70324.1 - 0.063 13.3 0.0 0.14 12.1 0.0 1.5 1 1 0 1 1 1 0 Suppressor of fused protein (SUFU) DHO_dh PF01180.21 ABK70324.1 - 0.18 11.0 0.4 12 5.0 0.0 2.2 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Acyl-CoA_dh_1 PF00441.24 ABK70325.1 - 2.6e-23 82.9 1.0 1e-22 81.0 1.3 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK70325.1 - 1.4e-14 54.7 1.2 3.6e-14 53.4 0.4 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ABK70325.1 - 1.1e-09 38.7 2.6 5.2e-09 36.5 2.6 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Bac_luciferase PF00296.20 ABK70326.1 - 5.9e-51 173.8 0.3 9.2e-51 173.1 0.3 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase Cutinase PF01083.22 ABK70327.1 - 9.8e-14 51.7 0.0 1.5e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 ABK70327.1 - 1.7e-05 24.5 0.0 2.2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain FSH1 PF03959.13 ABK70327.1 - 0.0095 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) CwsA PF10814.8 ABK70327.1 - 0.25 11.5 3.0 0.55 10.4 3.0 1.6 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA UPF0258 PF06789.12 ABK70327.1 - 6.1 7.0 5.1 8.6 6.5 4.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0258) Ferritin PF00210.24 ABK70328.1 - 2e-34 118.6 5.0 2.3e-34 118.4 5.0 1.0 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 ABK70328.1 - 0.015 15.7 2.7 0.044 14.2 2.7 1.7 1 1 0 1 1 1 0 Rubrerythrin DUF455 PF04305.14 ABK70328.1 - 0.087 12.4 0.2 0.14 11.7 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF455) adh_short PF00106.25 ABK70329.1 - 1.3e-38 132.4 0.0 2.1e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK70329.1 - 3.6e-26 92.2 0.1 6.5e-26 91.3 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK70329.1 - 7.5e-09 35.8 0.5 1.5e-08 34.8 0.5 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK70329.1 - 2.6e-06 27.1 0.0 5.7e-06 26.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ABK70329.1 - 2.7e-06 27.4 0.4 4.9e-06 26.6 0.2 1.6 1 1 1 2 2 2 1 NAD(P)H-binding LytR_C PF13399.6 ABK70329.1 - 0.028 15.4 0.2 4.7 8.3 0.0 3.0 3 0 0 3 3 3 0 LytR cell envelope-related transcriptional attenuator RmlD_sub_bind PF04321.17 ABK70329.1 - 0.04 13.0 0.1 0.079 12.0 0.1 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain PAP_PilO PF06864.12 ABK70329.1 - 0.041 12.7 0.1 0.069 12.0 0.0 1.4 2 0 0 2 2 2 0 Pilin accessory protein (PilO) Gln-synt_C PF00120.24 ABK70330.1 - 2e-86 290.2 0.0 2.4e-86 289.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 ABK70330.1 - 0.0062 16.3 0.0 0.015 15.1 0.0 1.6 1 1 0 1 1 1 1 Glutamine synthetase N-terminal domain Gln-synt_N PF03951.19 ABK70330.1 - 0.011 15.4 0.1 0.026 14.3 0.1 1.6 1 0 0 1 1 1 0 Glutamine synthetase, beta-Grasp domain Pro_CA PF00484.19 ABK70331.1 - 5.4e-37 127.5 0.2 6.6e-37 127.2 0.2 1.1 1 0 0 1 1 1 1 Carbonic anhydrase ECH_1 PF00378.20 ABK70332.1 - 4.4e-49 167.1 0.0 5.2e-49 166.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK70332.1 - 3.6e-35 122.0 1.0 8.6e-32 110.9 0.8 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase DUF4194 PF13835.6 ABK70333.1 - 1.3e-39 135.6 7.9 1.6e-39 135.3 7.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4194) KicB PF03882.14 ABK70333.1 - 0.054 13.7 0.9 0.28 11.4 0.6 2.1 2 0 0 2 2 2 0 MukF winged-helix domain TGT PF01702.18 ABK70334.1 - 1.6e-117 392.6 0.0 1.5e-116 389.4 0.0 1.9 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase Peptidase_M20 PF01546.28 ABK70335.1 - 1.8e-29 102.9 0.2 2.5e-29 102.4 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ABK70335.1 - 2.4e-15 56.4 0.0 5.1e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF4232 PF14016.6 ABK70335.1 - 0.16 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) Methyltransf_2 PF00891.18 ABK70336.1 - 3.8e-33 114.6 0.0 5.1e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain MarR_2 PF12802.7 ABK70336.1 - 8.8e-05 22.3 0.0 0.00041 20.2 0.0 2.1 1 0 0 1 1 1 1 MarR family Dimerisation2 PF16864.5 ABK70336.1 - 0.00014 21.7 0.0 0.0003 20.7 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain HTH_IclR PF09339.10 ABK70336.1 - 0.059 13.2 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain Methyltransf_12 PF08242.12 ABK70336.1 - 0.066 14.0 0.0 0.3 11.9 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain Sigma70_r2 PF04542.14 ABK70338.1 - 8.5e-14 51.1 0.9 2e-13 49.9 0.9 1.7 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 ABK70338.1 - 4e-08 32.8 0.9 9.1e-08 31.7 0.9 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 ABK70338.1 - 7.9e-06 25.3 1.0 7.9e-06 25.3 1.0 2.6 4 0 0 4 4 4 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 ABK70338.1 - 0.0067 16.3 1.3 0.012 15.5 1.3 1.4 1 0 0 1 1 1 1 ECF sigma factor GerE PF00196.19 ABK70338.1 - 0.02 14.4 0.1 0.045 13.3 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family TPR_16 PF13432.6 ABK70338.1 - 3.3 8.4 17.0 17 6.2 1.6 4.8 4 1 0 4 4 4 0 Tetratricopeptide repeat MFS_1 PF07690.16 ABK70339.1 - 9e-09 34.7 41.0 9e-09 34.7 41.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Prenyltransf PF01255.19 ABK70340.1 - 1.5e-69 233.9 0.0 1.8e-69 233.7 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase AlaDh_PNT_C PF01262.21 ABK70341.1 - 3.1e-68 229.3 5.6 5.1e-68 228.6 5.6 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 ABK70341.1 - 9.4e-47 158.7 0.6 1.9e-46 157.7 0.1 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 ABK70341.1 - 1e-33 115.7 10.8 4.7e-33 113.5 10.8 2.2 1 0 0 1 1 1 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 ABK70341.1 - 0.0022 17.4 0.2 0.44 9.9 0.0 2.5 1 1 1 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 ABK70341.1 - 1 9.3 5.3 2.1 8.4 0.6 3.5 3 1 0 3 3 3 0 Zinc-binding dehydrogenase DDE_Tnp_ISL3 PF01610.17 ABK70342.1 - 1.6e-64 217.9 0.0 2.1e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Transposase zf-ISL3 PF14690.6 ABK70342.1 - 1.1e-09 38.8 4.6 1.8e-09 38.1 2.5 2.5 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HTH_Tnp_ISL3 PF13542.6 ABK70342.1 - 2.4e-08 33.2 1.6 7e-08 31.8 1.6 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 VWA_2 PF13519.6 ABK70345.1 - 1.7e-19 70.4 0.0 6.9e-19 68.5 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 ABK70345.1 - 2.7e-17 63.6 0.0 3.9e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain BatA PF07584.11 ABK70345.1 - 3e-07 30.7 5.4 3e-07 30.7 5.4 2.2 2 0 0 2 2 2 1 Aerotolerance regulator N-terminal Ssl1 PF04056.14 ABK70345.1 - 0.052 13.4 0.0 0.13 12.1 0.0 1.6 2 0 0 2 2 2 0 Ssl1-like DUF4381 PF14316.6 ABK70345.1 - 0.053 13.8 1.0 0.053 13.8 1.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) AAA_assoc_2 PF16193.5 ABK70345.1 - 0.13 12.6 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA C-terminal domain FixQ PF05545.11 ABK70345.1 - 0.25 11.3 2.2 0.83 9.7 2.2 1.9 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DUF444 PF04285.12 ABK70345.1 - 0.31 10.1 0.1 0.96 8.5 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF444) DUF4131 PF13567.6 ABK70345.1 - 0.69 9.5 8.2 0.047 13.3 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) PPE PF00823.19 ABK70346.1 - 0.032 14.3 2.7 0.065 13.3 2.7 1.4 1 0 0 1 1 1 0 PPE family cEGF PF12662.7 ABK70347.1 - 0.16 11.9 1.3 15 5.6 0.1 2.2 2 0 0 2 2 2 0 Complement Clr-like EGF-like DoxX PF07681.12 ABK70348.1 - 7.1e-13 49.0 7.8 7.1e-13 49.0 7.8 1.6 2 0 0 2 2 2 1 DoxX TMEM239 PF15841.5 ABK70348.1 - 0.00016 21.6 2.3 0.0002 21.3 1.4 1.6 1 1 1 2 2 2 1 Transmembrane protein 239 family DoxD PF04173.13 ABK70348.1 - 0.00017 21.5 0.3 0.00017 21.5 0.3 1.5 2 0 0 2 2 2 1 TQO small subunit DoxD IMS PF00817.20 ABK70349.1 - 1.7e-39 135.2 0.0 7.7e-39 133.1 0.0 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 ABK70349.1 - 4.6e-10 40.2 0.2 9.5e-10 39.2 0.2 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DNA_pol_lambd_f PF10391.9 ABK70349.1 - 7.4e-05 22.5 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.6 ABK70349.1 - 0.00011 22.7 0.0 0.00029 21.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain IMS_HHH PF11798.8 ABK70349.1 - 0.00066 19.9 0.1 0.0024 18.1 0.0 2.1 3 0 0 3 3 3 1 IMS family HHH motif Cdd1 PF11731.8 ABK70349.1 - 0.0042 17.3 0.0 0.0089 16.2 0.0 1.5 1 0 0 1 1 1 1 Pathogenicity locus FMO-like PF00743.19 ABK70350.1 - 3.1e-18 65.5 0.0 5.7e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 ABK70350.1 - 7.4e-16 58.2 0.0 5.7e-14 52.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ABK70350.1 - 3.7e-15 56.0 0.0 1.6e-13 50.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ABK70350.1 - 1.4e-11 44.5 0.4 1.2e-10 41.5 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ABK70350.1 - 1.6e-10 41.1 11.6 0.00085 19.0 0.7 3.2 1 1 2 3 3 3 3 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ABK70350.1 - 1.1e-09 37.9 0.1 2.4e-08 33.5 0.3 2.6 2 1 0 2 2 2 1 Lycopene cyclase protein K_oxygenase PF13434.6 ABK70350.1 - 1.7e-09 37.3 0.3 5e-07 29.2 0.0 2.9 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 ABK70350.1 - 1.8e-08 34.6 0.7 4.2e-06 26.8 0.1 4.0 4 1 0 4 4 3 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 ABK70350.1 - 2.8e-07 30.1 0.3 0.0043 16.3 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 ABK70350.1 - 2.4e-06 26.9 0.1 4.2e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 ABK70350.1 - 3.7e-06 26.5 0.3 0.031 13.6 0.0 2.2 1 1 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 ABK70350.1 - 0.00018 20.4 1.1 0.0025 16.6 0.4 2.6 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.17 ABK70350.1 - 0.00021 20.6 0.3 0.0045 16.3 0.1 2.5 3 0 0 3 3 3 1 Thi4 family Pyr_redox PF00070.27 ABK70350.1 - 0.0017 18.9 1.8 0.085 13.4 0.3 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ABK70350.1 - 0.0028 16.8 0.1 0.052 12.6 0.3 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 ABK70350.1 - 0.0056 16.0 1.9 0.025 13.9 0.1 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ABK70350.1 - 0.014 14.7 0.1 0.17 11.2 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 ABK70350.1 - 0.067 12.5 0.6 0.16 11.3 0.6 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.16 ABK70350.1 - 0.26 10.9 1.2 3.2 7.4 0.2 2.6 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Thiolase_N PF00108.23 ABK70351.1 - 5.1e-43 147.3 0.2 7.4e-43 146.8 0.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ABK70351.1 - 2.1e-30 104.9 0.0 3.7e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain HGTP_anticodon PF03129.20 ABK70352.1 - 3.6e-22 78.3 0.0 6.7e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 ABK70352.1 - 1.9e-07 31.2 0.0 4.1e-07 30.1 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Paired_CXXCH_1 PF09699.10 ABK70352.1 - 0.072 12.9 0.2 0.15 11.8 0.2 1.5 1 0 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) EAL PF00563.20 ABK70353.1 - 0.12 11.9 0.0 0.35 10.3 0.0 1.7 1 1 1 2 2 2 0 EAL domain Formyl_trans_N PF00551.19 ABK70354.1 - 5.3e-47 159.9 0.0 6e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase Peptidase_M28 PF04389.17 ABK70355.1 - 5e-47 160.2 0.0 6.8e-47 159.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ABK70355.1 - 4.8e-15 55.4 2.3 1.3e-14 53.9 2.3 1.8 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 ABK70355.1 - 2.5e-05 24.1 0.0 5.7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF4910 PF16254.5 ABK70355.1 - 0.022 13.6 0.0 0.1 11.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4910) Beta-lactamase PF00144.24 ABK70356.1 - 2.4e-67 227.5 3.3 3.6e-67 226.9 3.3 1.2 1 0 0 1 1 1 1 Beta-lactamase TetR_C_29 PF17938.1 ABK70357.1 - 0.0021 18.1 0.0 0.0034 17.5 0.0 1.3 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_11 PF16859.5 ABK70357.1 - 0.0029 17.9 1.4 0.0061 16.9 0.3 1.8 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_21 PF17926.1 ABK70357.1 - 0.0043 17.2 0.1 0.0051 16.9 0.1 1.2 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain YAF2_RYBP PF17219.3 ABK70357.1 - 0.2 11.3 0.1 0.39 10.3 0.1 1.4 1 0 0 1 1 1 0 Yaf2/RYBP C-terminal binding motif FCD PF07729.12 ABK70358.1 - 2e-31 109.0 4.5 3.6e-31 108.2 4.5 1.4 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 ABK70358.1 - 1.4e-15 56.7 0.2 1.4e-15 56.7 0.2 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family FaeA PF04703.12 ABK70358.1 - 0.0049 17.2 0.0 0.013 15.8 0.0 1.7 1 0 0 1 1 1 1 FaeA-like protein HTH_Crp_2 PF13545.6 ABK70358.1 - 0.033 14.2 0.1 0.28 11.2 0.0 2.7 2 1 0 2 2 2 0 Crp-like helix-turn-helix domain TrmB PF01978.19 ABK70358.1 - 0.046 13.6 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 ABK70358.1 - 0.087 12.4 0.4 0.28 10.8 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding RtcR PF06956.11 ABK70358.1 - 0.1 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Regulator of RNA terminal phosphate cyclase Phycobilisome PF00502.19 ABK70358.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.4 1 1 0 1 1 1 0 Phycobilisome protein Acyl-CoA_dh_1 PF00441.24 ABK70360.1 - 1.3e-46 158.6 4.7 1.9e-46 158.0 4.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK70360.1 - 2.1e-26 91.9 0.0 4.1e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ABK70360.1 - 2.3e-26 92.7 0.1 5.1e-26 91.5 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ABK70360.1 - 1.1e-21 77.5 8.4 1.9e-21 76.7 8.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MarR_2 PF12802.7 ABK70361.1 - 4.8e-14 52.0 0.9 1e-13 51.0 0.9 1.6 1 0 0 1 1 1 1 MarR family MarR PF01047.22 ABK70361.1 - 4.1e-10 39.4 0.1 6.5e-10 38.8 0.1 1.3 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 ABK70361.1 - 3.4e-07 29.7 0.0 1.3e-06 27.8 0.1 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_27 PF13463.6 ABK70361.1 - 1.8e-06 28.3 0.1 4.5e-06 27.1 0.1 1.7 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_20 PF12840.7 ABK70361.1 - 6.8e-05 22.8 0.5 0.00018 21.5 0.3 1.8 1 1 1 2 2 2 1 Helix-turn-helix domain TrmB PF01978.19 ABK70361.1 - 0.00061 19.6 0.0 0.0013 18.5 0.0 1.6 1 1 1 2 2 2 1 Sugar-specific transcriptional regulator TrmB LexA_DNA_bind PF01726.16 ABK70361.1 - 0.00073 19.3 0.9 0.0017 18.0 0.2 2.0 2 1 0 2 2 2 1 LexA DNA binding domain HTH_11 PF08279.12 ABK70361.1 - 0.0016 18.4 0.0 0.004 17.1 0.0 1.7 1 0 0 1 1 1 1 HTH domain HTH_Crp_2 PF13545.6 ABK70361.1 - 0.0016 18.3 0.1 0.003 17.5 0.1 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain GntR PF00392.21 ABK70361.1 - 0.0041 16.8 0.8 0.025 14.2 0.3 2.4 3 0 0 3 3 3 1 Bacterial regulatory proteins, gntR family HxlR PF01638.17 ABK70361.1 - 0.01 15.7 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 0 HxlR-like helix-turn-helix DUF4423 PF14394.6 ABK70361.1 - 0.012 15.3 0.1 0.019 14.7 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4423) DprA_WH PF17782.1 ABK70361.1 - 0.048 13.8 1.4 0.048 13.8 1.4 2.2 2 2 0 2 2 2 0 DprA winged helix domain SelB-wing_2 PF09106.11 ABK70361.1 - 0.055 13.7 0.4 0.055 13.7 0.4 1.7 2 0 0 2 2 1 0 Elongation factor SelB, winged helix Fe_dep_repress PF01325.19 ABK70361.1 - 0.097 12.9 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_IclR PF09339.10 ABK70361.1 - 0.2 11.5 2.8 0.19 11.6 0.6 2.1 3 0 0 3 3 3 0 IclR helix-turn-helix domain PAC2 PF09754.9 ABK70362.1 - 3.4e-56 190.6 0.0 4.1e-56 190.4 0.0 1.1 1 0 0 1 1 1 1 PAC2 family Dodecin PF07311.12 ABK70362.1 - 0.19 12.0 0.3 0.79 10.0 0.0 2.0 2 0 0 2 2 2 0 Dodecin Polyketide_cyc2 PF10604.9 ABK70363.1 - 0.0001 22.6 3.8 0.00012 22.4 3.3 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 ABK70363.1 - 0.052 13.7 0.6 0.059 13.6 0.6 1.3 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Acyltransferase PF01553.21 ABK70364.1 - 1.3e-29 102.5 0.0 1.8e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase SBP_bac_5 PF00496.22 ABK70365.1 - 6e-61 206.5 7.3 8e-61 206.1 7.3 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle DUF1548 PF07579.11 ABK70365.1 - 0.13 12.6 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1548) T7SS_ESX_EspC PF10824.8 ABK70366.1 - 2.7e-23 82.3 2.1 2.7e-23 82.3 2.1 3.2 2 1 2 4 4 4 1 Excreted virulence factor EspC, type VII ESX diderm Vinculin PF01044.19 ABK70366.1 - 0.0073 14.6 0.9 0.011 14.0 0.9 1.2 1 0 0 1 1 1 1 Vinculin family LUC7 PF03194.15 ABK70366.1 - 0.046 13.4 0.2 0.067 12.9 0.2 1.4 1 0 0 1 1 1 0 LUC7 N_terminus Perilipin PF03036.16 ABK70366.1 - 0.053 12.6 0.3 0.084 11.9 0.3 1.3 1 0 0 1 1 1 0 Perilipin family PTE PF02126.18 ABK70367.1 - 4.8e-125 416.9 0.7 5.5e-125 416.7 0.7 1.0 1 0 0 1 1 1 1 Phosphotriesterase family CMD PF02627.20 ABK70367.1 - 0.1 12.6 0.2 4.1 7.5 0.2 2.5 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family CSD PF00313.22 ABK70368.1 - 4.8e-16 58.4 0.0 6.8e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 ABK70368.1 - 0.00093 18.8 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease B OB domain FIN1 PF17300.2 ABK70369.1 - 0.1 12.1 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 cNMP_binding PF00027.29 ABK70370.1 - 1.3e-17 63.6 0.0 3.4e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Acetyltransf_3 PF13302.7 ABK70370.1 - 6.8e-08 33.3 0.0 1.2e-07 32.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ABK70370.1 - 0.00017 21.8 0.0 0.00029 21.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ABK70370.1 - 0.0038 17.6 0.0 0.01 16.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AHSA1 PF08327.11 ABK70371.1 - 2.8e-17 63.1 0.1 3.6e-17 62.8 0.1 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 ABK70371.1 - 1.6e-08 34.9 2.4 1.9e-08 34.7 1.9 1.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 ABK70371.1 - 0.06 13.6 0.0 0.083 13.1 0.0 1.4 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Amidase PF01425.21 ABK70372.1 - 1.4e-85 288.0 0.3 1.8e-85 287.6 0.3 1.0 1 0 0 1 1 1 1 Amidase DUF2236 PF09995.9 ABK70373.1 - 2.5e-25 90.0 10.3 2.5e-25 90.0 10.3 2.0 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) AA_permease_2 PF13520.6 ABK70374.1 - 5.7e-41 140.7 44.7 6.9e-41 140.5 44.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ABK70374.1 - 3.7e-32 111.5 39.4 6.9e-32 110.7 39.4 1.3 1 1 0 1 1 1 1 Amino acid permease NAGPA PF09992.9 ABK70375.1 - 5.6e-12 46.2 0.5 5.7e-11 42.9 0.4 2.3 2 1 0 2 2 2 1 Phosphodiester glycosidase EF_TS PF00889.19 ABK70376.1 - 3.7e-66 222.7 2.1 4.5e-66 222.4 2.1 1.1 1 0 0 1 1 1 1 Elongation factor TS DUF348 PF03990.14 ABK70376.1 - 0.0083 15.8 2.5 0.56 10.0 0.1 2.6 2 0 0 2 2 2 2 G5-linked-Ubiquitin-like domain ADH_zinc_N PF00107.26 ABK70377.1 - 8.9e-22 77.5 0.0 2e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ABK70377.1 - 9e-15 55.9 0.0 1.8e-14 54.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ABK70377.1 - 4.1e-12 46.0 0.1 1.1e-11 44.5 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 ABK70377.1 - 0.032 14.1 0.0 0.069 13.1 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase YAcAr PF10686.9 ABK70377.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family TrkA_N PF02254.18 ABK70379.1 - 1.2e-23 83.6 0.3 1.8e-23 83.0 0.3 1.2 1 0 0 1 1 1 1 TrkA-N domain TrkA_C PF02080.21 ABK70379.1 - 6.9e-07 29.0 0.0 1.6e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 TrkA-C domain UDPG_MGDP_dh_N PF03721.14 ABK70379.1 - 0.00012 21.7 0.0 0.00021 20.9 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.24 ABK70379.1 - 0.00088 18.9 0.2 0.19 11.3 0.1 2.0 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 ABK70379.1 - 0.0019 18.7 0.5 0.0064 17.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 ABK70379.1 - 0.002 18.0 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 ABK70379.1 - 0.002 17.5 0.1 0.0032 16.9 0.1 1.3 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 ABK70379.1 - 0.0028 17.9 0.1 0.0069 16.6 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 ABK70379.1 - 0.0048 17.4 0.2 0.018 15.6 0.1 2.1 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 ABK70379.1 - 0.013 15.3 0.2 0.013 15.3 0.2 2.0 2 1 1 3 3 2 0 Rossmann-like domain NAD_binding_7 PF13241.6 ABK70379.1 - 0.014 15.9 0.1 0.022 15.2 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 ABK70379.1 - 0.022 14.1 0.0 0.047 13.0 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 ABK70379.1 - 0.025 15.1 0.0 0.046 14.2 0.0 1.6 1 1 0 1 1 1 0 XdhC Rossmann domain ApbA PF02558.16 ABK70379.1 - 0.025 14.2 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 ABK70379.1 - 0.026 13.8 0.1 0.031 13.5 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 ABK70379.1 - 0.032 14.4 0.0 0.057 13.6 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase FAD_binding_3 PF01494.19 ABK70379.1 - 0.035 13.3 0.3 0.071 12.3 0.2 1.4 1 1 0 1 1 1 0 FAD binding domain Epimerase PF01370.21 ABK70379.1 - 0.056 12.9 0.4 0.077 12.5 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_Gly3P_dh_N PF01210.23 ABK70379.1 - 0.072 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.21 ABK70379.1 - 0.073 12.4 0.2 0.098 11.9 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UBA PF00627.31 ABK70379.1 - 0.11 12.4 0.1 0.25 11.3 0.1 1.6 1 0 0 1 1 1 0 UBA/TS-N domain Acyl-CoA_dh_1 PF00441.24 ABK70380.1 - 1.9e-38 132.1 3.8 2.7e-38 131.5 3.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK70380.1 - 7.9e-20 70.9 0.0 2.7e-19 69.1 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ABK70380.1 - 1.2e-17 64.4 0.9 2.6e-17 63.3 0.9 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK70380.1 - 2.1e-08 34.8 0.0 8.8e-08 32.8 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 ABK70380.1 - 0.00026 20.8 0.0 0.00049 19.8 0.0 1.5 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Herpes_UL36 PF03586.13 ABK70380.1 - 0.13 11.5 0.1 0.2 10.9 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein MFS_1 PF07690.16 ABK70381.1 - 4.5e-28 98.2 59.2 3.2e-18 65.8 27.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK70381.1 - 1.8e-26 93.0 29.9 3.8e-25 88.7 8.8 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 ABK70381.1 - 2.1e-09 36.5 28.6 2.1e-09 36.5 28.6 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein HTH_30 PF13556.6 ABK70382.1 - 6.1e-20 70.8 0.0 1.8e-19 69.3 0.0 1.9 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain GGDEF_2 PF17853.1 ABK70382.1 - 2.9e-10 40.4 0.3 2.9e-10 40.4 0.3 2.4 3 0 0 3 3 3 1 GGDEF-like domain HTH_8 PF02954.19 ABK70382.1 - 0.094 12.5 0.1 0.38 10.6 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family Amdase PF17645.1 ABK70383.1 - 5.4e-18 65.4 0.0 6.6e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 Arylmalonate decarboxylase Asp_Glu_race PF01177.22 ABK70383.1 - 0.028 14.2 0.0 0.059 13.2 0.0 1.6 1 1 0 1 1 1 0 Asp/Glu/Hydantoin racemase ABC_tran PF00005.27 ABK70384.1 - 1.2e-33 116.5 0.0 1.9e-33 115.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 ABK70384.1 - 1.3e-14 54.1 0.8 4e-14 52.5 0.5 2.1 2 0 0 2 2 2 1 TOBE domain TOBE PF03459.17 ABK70384.1 - 0.00086 19.6 1.1 0.0055 17.0 0.2 2.5 2 1 0 2 2 2 1 TOBE domain TOBE_3 PF12857.7 ABK70384.1 - 0.0034 17.3 0.2 0.027 14.4 0.1 2.4 2 0 0 2 2 2 1 TOBE-like domain AAA_21 PF13304.6 ABK70384.1 - 0.0036 17.2 0.0 0.54 10.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ABK70384.1 - 0.036 14.3 0.1 0.15 12.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 ABK70384.1 - 0.043 13.7 0.0 0.063 13.2 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain Mg_chelatase PF01078.21 ABK70384.1 - 0.059 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 ABK70384.1 - 0.077 13.4 0.1 0.14 12.6 0.1 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Alk_phosphatase PF00245.20 ABK70385.1 - 6.2e-117 391.1 4.5 8.6e-117 390.6 4.5 1.2 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 ABK70385.1 - 6.4e-06 25.7 2.6 6.5e-05 22.4 1.9 2.3 2 1 0 2 2 2 1 Metalloenzyme superfamily Sulfatase PF00884.23 ABK70385.1 - 0.0018 17.7 1.8 0.13 11.6 1.8 2.6 1 1 0 1 1 1 1 Sulfatase DUF2079 PF09852.9 ABK70386.1 - 0.11 11.3 0.0 0.13 11.1 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) Fer2 PF00111.27 ABK70387.1 - 2.2e-14 53.2 0.1 3.1e-14 52.7 0.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Cys_Met_Meta_PP PF01053.20 ABK70388.1 - 7.7e-130 432.8 0.0 8.6e-130 432.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 ABK70388.1 - 5.4e-06 25.9 0.2 8.3e-06 25.3 0.1 1.3 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 ABK70388.1 - 0.00067 18.7 0.0 0.003 16.6 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 ABK70388.1 - 0.0089 15.2 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II SelA PF03841.13 ABK70388.1 - 0.11 11.5 0.1 0.27 10.2 0.0 1.6 2 0 0 2 2 2 0 L-seryl-tRNA selenium transferase APH PF01636.23 ABK70389.1 - 3.4e-16 59.9 6.3 5.2e-16 59.3 6.3 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 ABK70389.1 - 2e-14 53.6 0.0 5.6e-09 35.7 0.0 2.3 2 1 0 2 2 2 2 Ecdysteroid kinase DUF1679 PF07914.11 ABK70389.1 - 1.7e-09 37.0 0.0 2.6e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) adh_short PF00106.25 ABK70390.1 - 7.7e-45 152.8 0.1 9.8e-45 152.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK70390.1 - 6.8e-33 114.2 0.5 8.5e-33 113.9 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK70390.1 - 3e-08 33.8 0.9 4.4e-08 33.3 0.9 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK70390.1 - 2e-07 30.7 0.3 3.1e-07 30.1 0.3 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ABK70390.1 - 6e-07 29.5 1.3 7.6e-07 29.2 1.3 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 ABK70390.1 - 0.00071 19.8 1.4 0.0013 19.0 1.3 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain HEM4 PF02602.15 ABK70390.1 - 0.016 14.5 0.2 0.025 13.9 0.2 1.4 1 1 0 1 1 1 0 Uroporphyrinogen-III synthase HemD ADH_zinc_N PF00107.26 ABK70390.1 - 0.022 14.7 2.1 0.044 13.8 2.1 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase F420_oxidored PF03807.17 ABK70390.1 - 0.081 13.5 1.0 0.86 10.2 0.2 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TetR_N PF00440.23 ABK70391.1 - 2.9e-16 59.0 1.1 4.9e-16 58.3 0.4 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family Hemerythrin PF01814.23 ABK70391.1 - 0.08 13.6 0.3 0.12 13.0 0.3 1.4 1 1 0 1 1 1 0 Hemerythrin HHE cation binding domain Transposase_mut PF00872.18 ABK70392.1 - 2.3e-121 405.3 0.0 2.8e-121 405.0 0.0 1.0 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 ABK70392.1 - 1.6e-08 34.9 0.0 4e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain DUF4375 PF14300.6 ABK70392.1 - 0.069 13.4 0.0 12 6.2 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4375) FMO-like PF00743.19 ABK70393.1 - 5.9e-19 67.9 0.0 5.8e-17 61.3 0.0 3.0 1 1 1 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ABK70393.1 - 1.3e-15 57.5 0.0 1.1e-14 54.4 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ABK70393.1 - 3e-14 52.9 0.0 5.7e-11 42.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ABK70393.1 - 5.5e-10 38.9 0.0 1.5e-07 30.9 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ABK70393.1 - 1.2e-09 38.3 0.0 3.9e-08 33.4 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ABK70393.1 - 4.4e-07 29.8 5.4 0.0003 20.5 0.1 4.3 4 1 0 4 4 4 1 FAD dependent oxidoreductase Thi4 PF01946.17 ABK70393.1 - 5.1e-07 29.2 0.0 2.4e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 ABK70393.1 - 1.8e-06 28.4 0.0 0.02 15.4 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ABK70393.1 - 0.00011 21.4 0.0 0.009 15.1 0.0 3.3 4 0 0 4 4 4 1 FAD binding domain Lycopene_cycl PF05834.12 ABK70393.1 - 0.00032 19.9 0.5 0.48 9.4 0.0 3.8 4 0 0 4 4 4 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 ABK70393.1 - 0.00099 19.1 1.6 0.94 9.5 0.0 3.4 4 0 0 4 4 4 2 FAD-NAD(P)-binding FAD_oxidored PF12831.7 ABK70393.1 - 0.0056 16.1 0.0 0.028 13.8 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 ABK70393.1 - 0.0095 15.1 0.3 1.2 8.1 0.0 2.6 3 1 0 3 3 3 1 Glucose inhibited division protein A Mqo PF06039.15 ABK70393.1 - 0.016 13.8 0.0 4 5.9 0.0 2.2 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_3 PF01494.19 ABK70393.1 - 0.047 12.9 0.0 1.8 7.7 0.0 2.4 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.6 ABK70393.1 - 0.1 13.0 0.0 0.31 11.5 0.0 1.9 2 1 0 2 2 2 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 ABK70393.1 - 0.22 11.6 0.1 5.9 7.0 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 ABK70393.1 - 0.29 9.8 0.2 0.83 8.3 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein BPD_transp_1 PF00528.22 ABK70394.1 - 2.8e-15 56.5 18.0 2.9e-15 56.5 16.3 1.7 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component SPC25 PF06703.11 ABK70394.1 - 0.36 10.6 0.1 0.36 10.6 0.1 1.8 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) ABC_tran PF00005.27 ABK70395.1 - 2e-24 86.6 0.0 2.7e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK70395.1 - 2.6e-07 30.7 1.2 0.0019 18.1 0.2 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ABK70395.1 - 0.0003 21.2 0.2 0.00091 19.7 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 ABK70395.1 - 0.023 14.1 0.0 0.71 9.3 0.0 2.1 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ABK70395.1 - 0.033 14.5 0.1 0.14 12.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ABK70395.1 - 0.098 12.9 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ABK70395.1 - 0.11 13.0 0.0 0.18 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ABK70395.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 ABK70395.1 - 0.12 12.1 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain DUF3584 PF12128.8 ABK70395.1 - 0.12 9.8 0.0 0.18 9.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA PF00004.29 ABK70395.1 - 0.15 12.5 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Oxidored_molyb PF00174.19 ABK70396.1 - 1.9e-25 89.4 0.0 2.9e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain DUF4405 PF14358.6 ABK70396.1 - 0.39 11.3 20.3 2 9.0 5.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) Ni_hydr_CYTB PF01292.20 ABK70396.1 - 0.68 9.5 17.6 5.6 6.5 17.6 2.0 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 PepSY_TM PF03929.16 ABK70396.1 - 6.5 6.3 9.8 9.7 5.8 8.3 2.0 1 1 0 1 1 1 0 PepSY-associated TM region TetR_N PF00440.23 ABK70397.1 - 1.9e-11 43.6 0.3 3.8e-11 42.6 0.3 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_7 PF02796.15 ABK70397.1 - 3.8e-06 26.9 0.0 8e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.6 ABK70397.1 - 5.8e-05 22.8 0.4 0.00037 20.2 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_22 PF13309.6 ABK70397.1 - 0.00073 19.6 0.0 0.0028 17.7 0.0 1.9 2 0 0 2 2 2 1 HTH domain HTH_29 PF13551.6 ABK70397.1 - 0.0031 17.5 0.4 0.0072 16.3 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_8 PF02954.19 ABK70397.1 - 0.0042 16.8 0.3 0.016 15.0 0.0 2.2 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family HTH_11 PF08279.12 ABK70397.1 - 0.01 15.8 0.0 0.031 14.2 0.0 1.8 1 0 0 1 1 1 1 HTH domain HTH_17 PF12728.7 ABK70397.1 - 0.01 16.0 0.2 0.026 14.7 0.0 1.8 2 0 0 2 2 1 0 Helix-turn-helix domain MarR_2 PF12802.7 ABK70397.1 - 0.011 15.6 0.1 0.027 14.4 0.1 1.6 1 0 0 1 1 1 0 MarR family HTH_38 PF13936.6 ABK70397.1 - 0.014 15.1 0.9 0.023 14.4 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_3 PF01381.22 ABK70397.1 - 0.014 15.4 0.0 0.056 13.5 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix HTH_32 PF13565.6 ABK70397.1 - 0.058 14.0 0.1 3.2 8.5 0.0 2.8 3 0 0 3 3 3 0 Homeodomain-like domain Sigma70_r4_2 PF08281.12 ABK70397.1 - 0.066 12.9 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Crp_2 PF13545.6 ABK70397.1 - 0.076 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_28 PF13518.6 ABK70397.1 - 0.089 12.9 2.1 0.11 12.7 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 ABK70397.1 - 0.093 12.2 0.1 0.51 9.8 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 CENP-B_N PF04218.13 ABK70397.1 - 0.22 11.2 0.0 0.45 10.2 0.0 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_AsnC-type PF13404.6 ABK70397.1 - 0.35 10.7 0.1 0.35 10.7 0.1 2.1 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_31 PF13560.6 ABK70397.1 - 0.52 10.7 4.4 8.6 6.8 1.0 3.4 2 1 0 2 2 2 0 Helix-turn-helix domain MerR PF00376.23 ABK70397.1 - 2.4 8.0 5.1 0.51 10.2 0.3 2.4 4 0 0 4 4 3 0 MerR family regulatory protein TetR_C_11 PF16859.5 ABK70399.1 - 5.6e-23 81.4 3.8 5.6e-23 81.4 3.8 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK70399.1 - 4.3e-11 42.4 0.0 1.8e-10 40.4 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family MLTR_LBD PF17765.1 ABK70400.1 - 6.6e-56 189.0 1.8 1.2e-55 188.2 1.8 1.4 1 0 0 1 1 1 1 MmyB-like transcription regulator ligand binding domain HTH_31 PF13560.6 ABK70400.1 - 1.7e-18 66.7 5.7 4e-18 65.5 5.7 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 ABK70400.1 - 3.9e-07 30.0 0.0 7.4e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 ABK70400.1 - 0.0014 18.6 0.0 0.0027 17.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Sugar_tr PF00083.24 ABK70401.1 - 4.2e-42 144.6 10.6 6e-42 144.1 10.5 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ABK70401.1 - 9.3e-39 133.3 72.2 8.6e-33 113.7 36.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Orn_Arg_deC_N PF02784.16 ABK70402.1 - 0.00018 21.0 0.3 0.0017 17.7 0.0 1.9 1 1 1 2 2 2 2 Pyridoxal-dependent decarboxylase, pyridoxal binding domain ParD_like PF11903.8 ABK70403.1 - 5.1e-23 80.9 2.2 8.9e-23 80.2 2.2 1.4 1 1 0 1 1 1 1 ParD-like antitoxin of type II bacterial toxin-antitoxin system DUF5122 PF17164.4 ABK70403.1 - 0.044 14.1 0.6 0.066 13.5 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5122) beta-propeller WES_acyltransf PF03007.16 ABK70404.1 - 1.7e-76 257.5 0.0 3.1e-76 256.6 0.0 1.4 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 ABK70404.1 - 4.7e-38 130.4 0.0 7.1e-38 129.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) DUF2231 PF09990.9 ABK70405.1 - 0.025 15.0 4.0 0.31 11.5 0.5 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) NUDIX PF00293.28 ABK70406.1 - 1.5e-09 38.0 0.0 2.2e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Atracotoxin PF05353.11 ABK70407.1 - 0.2 11.8 1.6 45 4.2 0.0 3.2 3 0 0 3 3 3 0 Delta Atracotoxin TetR_N PF00440.23 ABK70408.1 - 4.7e-06 26.3 0.0 1.3e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family DUF4446 PF14584.6 ABK70410.1 - 0.07 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) FCD PF07729.12 ABK70412.1 - 3.5e-17 63.0 22.6 6.8e-17 62.1 22.6 1.4 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 ABK70412.1 - 7.6e-14 51.1 0.3 1.6e-13 50.1 0.0 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_27 PF13463.6 ABK70412.1 - 0.011 16.2 0.0 0.04 14.4 0.0 2.0 1 1 1 2 2 2 0 Winged helix DNA-binding domain HTH_IclR PF09339.10 ABK70412.1 - 0.013 15.3 0.9 0.68 9.8 0.0 2.8 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_20 PF12840.7 ABK70412.1 - 0.018 15.1 0.6 0.16 12.1 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain LexA_DNA_bind PF01726.16 ABK70412.1 - 0.026 14.3 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 LexA DNA binding domain HTH_24 PF13412.6 ABK70412.1 - 0.027 14.0 0.2 0.07 12.7 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 ABK70412.1 - 0.059 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Crp_2 PF13545.6 ABK70412.1 - 0.059 13.3 0.1 0.18 11.8 0.0 1.9 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain TetR_N PF00440.23 ABK70413.1 - 5.8e-06 26.0 0.1 5.8e-06 26.0 0.1 2.6 3 0 0 3 3 3 1 Bacterial regulatory proteins, tetR family TetR_C_8 PF14278.6 ABK70413.1 - 0.012 15.7 0.0 0.042 13.9 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region PUCC PF03209.15 ABK70413.1 - 0.025 13.6 0.3 0.03 13.3 0.3 1.2 1 0 0 1 1 1 0 PUCC protein LysR_substrate PF03466.20 ABK70414.1 - 1.3e-34 119.4 3.5 1.7e-34 119.0 3.5 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 ABK70414.1 - 4.3e-19 68.2 3.5 1e-18 67.0 3.5 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_28 PF13518.6 ABK70414.1 - 0.072 13.2 0.0 0.23 11.6 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain MLTR_LBD PF17765.1 ABK70416.1 - 4.6e-38 131.0 2.4 5.5e-38 130.7 0.8 1.8 2 0 0 2 2 2 1 MmyB-like transcription regulator ligand binding domain HTH_31 PF13560.6 ABK70416.1 - 5.8e-18 65.0 3.8 1.2e-17 63.9 2.8 2.2 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 ABK70416.1 - 2.1e-07 30.9 0.0 4e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 ABK70416.1 - 0.0011 18.9 0.2 0.004 17.1 0.0 2.0 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_26 PF13443.6 ABK70416.1 - 0.017 15.6 0.0 0.033 14.6 0.0 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Pirin PF02678.16 ABK70417.1 - 1.8e-36 124.4 0.4 3.1e-36 123.6 0.4 1.3 1 0 0 1 1 1 1 Pirin Pirin_C_2 PF17954.1 ABK70417.1 - 4.4e-08 33.2 0.0 1.1e-07 32.0 0.0 1.6 2 0 0 2 2 2 1 Quercetinase C-terminal cupin domain Cupin_2 PF07883.11 ABK70417.1 - 0.00062 19.4 3.0 0.022 14.5 0.3 3.4 2 2 1 3 3 3 1 Cupin domain AIRS_C PF02769.22 ABK70418.1 - 1.5e-18 67.4 1.0 1.5e-18 67.4 1.0 1.5 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 ABK70418.1 - 6e-17 62.1 1.9 6e-17 62.1 1.9 1.7 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain Prot_ATP_ID_OB PF16450.5 ABK70418.1 - 0.1 12.5 0.4 0.78 9.7 0.1 2.5 2 1 0 2 2 2 0 Proteasomal ATPase OB C-terminal domain GcpE PF04551.14 ABK70419.1 - 1.9e-131 438.3 0.1 2.2e-131 438.1 0.1 1.0 1 0 0 1 1 1 1 GcpE protein MR_MLE_C PF13378.6 ABK70419.1 - 0.097 12.2 0.3 1.7 8.2 0.2 2.5 1 1 2 3 3 3 0 Enolase C-terminal domain-like zf-RING_7 PF02591.15 ABK70419.1 - 0.13 12.5 0.1 0.38 11.0 0.1 1.9 1 0 0 1 1 1 0 C4-type zinc ribbon domain FtsK_SpoIIIE PF01580.18 ABK70420.1 - 8.9e-90 300.3 0.0 4.1e-58 196.6 0.0 4.8 4 1 0 4 4 4 3 FtsK/SpoIIIE family AAA_22 PF13401.6 ABK70420.1 - 1.7e-10 41.3 0.0 0.0049 17.1 0.0 3.9 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 ABK70420.1 - 3.4e-09 37.3 0.1 0.27 11.6 0.0 4.0 3 1 0 3 3 3 3 AAA ATPase domain NACHT PF05729.12 ABK70420.1 - 2.4e-06 27.5 0.0 0.0092 15.9 0.0 3.6 4 0 0 4 4 3 1 NACHT domain AAA_29 PF13555.6 ABK70420.1 - 3.2e-06 26.8 0.2 1.7 8.5 0.0 3.5 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_19 PF13245.6 ABK70420.1 - 2.6e-05 24.6 0.0 1.3 9.4 0.0 3.6 3 0 0 3 3 3 1 AAA domain TrwB_AAD_bind PF10412.9 ABK70420.1 - 7.1e-05 21.9 0.0 0.034 13.1 0.1 3.1 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain AAA_23 PF13476.6 ABK70420.1 - 0.0003 21.3 0.0 0.36 11.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 ABK70420.1 - 0.00048 19.3 0.0 5.9 5.9 0.0 3.6 3 0 0 3 3 3 1 Type II/IV secretion system protein Viral_helicase1 PF01443.18 ABK70420.1 - 0.00081 19.2 0.0 7.2 6.3 0.0 3.3 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 ABK70420.1 - 0.0012 19.4 0.0 0.75 10.3 0.0 3.1 3 0 0 3 3 3 1 ABC transporter ATPase_2 PF01637.18 ABK70420.1 - 0.0013 18.7 0.0 0.04 13.8 0.0 2.7 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea DUF87 PF01935.17 ABK70420.1 - 0.0025 18.0 0.0 0.011 15.9 0.0 2.0 2 0 0 2 2 2 1 Helicase HerA, central domain TniB PF05621.11 ABK70420.1 - 0.0031 17.0 0.0 0.63 9.4 0.0 2.8 3 0 0 3 3 3 1 Bacterial TniB protein RNA_helicase PF00910.22 ABK70420.1 - 0.0031 17.9 0.0 6.4 7.2 0.0 3.9 4 0 0 4 4 4 0 RNA helicase AAA_33 PF13671.6 ABK70420.1 - 0.0037 17.4 0.0 17 5.5 0.0 3.7 3 1 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 ABK70420.1 - 0.014 15.4 0.0 2.8 8.1 0.0 3.1 3 0 0 3 3 3 0 50S ribosome-binding GTPase Roc PF08477.13 ABK70420.1 - 0.016 15.4 0.0 0.14 12.4 0.0 2.3 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 ABK70420.1 - 0.02 14.5 0.0 3.6 7.1 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 ABK70420.1 - 0.024 14.6 0.0 4.9 7.2 0.0 3.4 3 1 0 3 3 3 0 AAA domain AAA_18 PF13238.6 ABK70420.1 - 0.038 14.5 0.0 14 6.3 0.0 3.7 4 0 0 4 4 4 0 AAA domain AAA_24 PF13479.6 ABK70420.1 - 0.048 13.4 0.0 4.4 7.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 ABK70420.1 - 0.066 12.7 0.0 16 4.9 0.0 3.0 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_10 PF12846.7 ABK70420.1 - 0.092 11.6 0.0 17 4.2 0.0 2.9 3 0 0 3 3 3 0 AAA-like domain Bac_export_3 PF01313.19 ABK70420.1 - 0.16 11.9 3.1 0.31 11.0 3.1 1.4 1 0 0 1 1 1 0 Bacterial export proteins, family 3 Glyco_hydro_76 PF03663.14 ABK70420.1 - 0.18 11.3 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 76 MobB PF03205.14 ABK70420.1 - 0.18 11.7 0.7 0.34 10.8 0.0 1.7 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.20 ABK70420.1 - 0.23 10.6 0.0 8.7 5.4 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit TMEM100 PF16311.5 ABK70420.1 - 0.27 10.8 0.8 0.51 9.9 0.8 1.3 1 0 0 1 1 1 0 Transmembrane protein 100 FliP PF00813.20 ABK70420.1 - 0.65 9.9 7.0 1.1 9.0 7.0 1.3 1 0 0 1 1 1 0 FliP family MdcG PF10620.9 ABK70421.1 - 2.5e-46 158.0 6.8 2.8e-46 157.8 6.8 1.0 1 0 0 1 1 1 1 Phosphoribosyl-dephospho-CoA transferase MdcG Amidinotransf PF02274.17 ABK70422.1 - 1e-109 366.8 0.0 1.1e-109 366.6 0.0 1.0 1 0 0 1 1 1 1 Amidinotransferase PAD_porph PF04371.15 ABK70422.1 - 0.0011 18.3 0.1 0.0032 16.8 0.1 1.7 1 1 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase adh_short_C2 PF13561.6 ABK70424.1 - 1.9e-53 181.4 2.2 2.9e-53 180.8 2.2 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK70424.1 - 3.8e-43 147.2 3.7 7.2e-43 146.3 3.7 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK70424.1 - 6e-07 29.5 3.3 1.6e-05 24.9 3.3 2.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK70424.1 - 6.3e-06 25.8 0.1 1.5e-05 24.6 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ABK70424.1 - 0.005 16.0 0.1 0.0075 15.4 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain AdoHcyase_NAD PF00670.21 ABK70424.1 - 0.095 12.8 2.1 0.15 12.1 2.1 1.2 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain MlaD PF02470.20 ABK70425.1 - 3.7e-14 52.8 0.3 1e-13 51.4 0.3 1.8 1 0 0 1 1 1 1 MlaD protein Acyl-CoA_dh_M PF02770.19 ABK70427.1 - 9.6e-22 77.0 0.0 1.9e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ABK70427.1 - 1.4e-17 64.4 0.1 8.4e-17 61.9 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 ABK70427.1 - 9.3e-17 61.6 0.0 1.9e-16 60.6 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 ABK70427.1 - 0.064 12.9 0.0 0.097 12.3 0.0 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Abhydrolase_1 PF00561.20 ABK70428.1 - 4.9e-25 88.6 0.1 4.4e-22 79.0 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK70428.1 - 1.4e-21 78.1 14.2 2.1e-21 77.6 14.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK70428.1 - 2.2e-16 59.8 0.0 1.3e-13 50.8 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 SAM_2 PF07647.17 ABK70428.1 - 0.052 13.7 0.0 0.092 12.9 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DLH PF01738.18 ABK70428.1 - 0.071 12.6 0.1 12 5.3 0.1 3.0 2 1 0 2 2 2 0 Dienelactone hydrolase family Esterase PF00756.20 ABK70428.1 - 0.16 11.6 0.0 0.59 9.7 0.0 1.8 1 1 0 1 1 1 0 Putative esterase AXE1 PF05448.12 ABK70428.1 - 0.26 9.9 0.0 0.38 9.4 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF3071 PF11268.8 ABK70429.1 - 1e-59 201.3 2.4 1.3e-59 201.0 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3071) Trypan_PARP PF05887.11 ABK70429.1 - 0.015 15.3 9.0 0.024 14.6 9.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) HTH_15 PF12324.8 ABK70429.1 - 0.14 12.1 0.3 0.48 10.4 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase P22_Tail-4 PF11650.8 ABK70429.1 - 0.19 11.7 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 P22 tail accessory factor YiaAB PF05360.14 ABK70430.1 - 2.5e-16 59.7 5.4 3.1e-16 59.4 5.4 1.1 1 0 0 1 1 1 1 yiaA/B two helix domain 7TMR-DISM_7TM PF07695.11 ABK70430.1 - 0.0016 18.4 1.7 0.0017 18.3 1.7 1.0 1 0 0 1 1 1 1 7TM diverse intracellular signalling Claudin_2 PF13903.6 ABK70430.1 - 0.043 13.6 2.0 0.046 13.5 2.0 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction RseC_MucC PF04246.12 ABK70430.1 - 0.063 13.2 2.1 0.076 13.0 2.1 1.1 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC DsbD PF02683.15 ABK70431.1 - 4.4e-15 56.2 10.8 7.6e-15 55.4 10.8 1.3 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region PorA PF11271.8 ABK70431.1 - 3.1 7.0 9.5 2.6 7.2 2.0 2.5 2 0 0 2 2 2 0 Porin PorA TetR_C_14 PF17754.1 ABK70432.1 - 9.3e-11 41.7 0.5 9.3e-11 41.7 0.5 2.1 2 1 0 2 2 2 1 MftR C-terminal domain TetR_N PF00440.23 ABK70432.1 - 1.3e-07 31.3 0.3 4.2e-07 29.6 0.1 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_18 PF12833.7 ABK70432.1 - 0.024 14.9 0.2 0.073 13.3 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 ABK70432.1 - 0.026 14.5 0.0 0.05 13.6 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_23 PF13384.6 ABK70432.1 - 0.064 13.1 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_3 PF01381.22 ABK70432.1 - 0.072 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix Sigma70_r2 PF04542.14 ABK70433.1 - 3.8e-22 77.8 0.5 3.8e-22 77.8 0.5 1.5 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 ABK70433.1 - 2.6e-17 62.2 0.0 6.4e-17 61.0 0.0 1.6 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 ABK70433.1 - 7.2e-15 54.2 0.1 3.6e-14 52.0 0.0 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 ABK70433.1 - 0.00029 20.8 0.0 0.00064 19.6 0.0 1.7 1 1 0 1 1 1 1 ECF sigma factor HTH_23 PF13384.6 ABK70433.1 - 0.0033 17.2 0.1 0.0081 15.9 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_AsnC-type PF13404.6 ABK70433.1 - 0.052 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain TnsD PF15978.5 ABK70433.1 - 0.13 11.2 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Tn7-like transposition protein D CPSase_sm_chain PF00988.22 ABK70434.1 - 0.054 13.3 0.0 0.054 13.3 0.0 1.1 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase small chain, CPSase domain His_biosynth PF00977.21 ABK70435.1 - 4.7e-89 297.8 0.2 5.3e-89 297.6 0.2 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 ABK70435.1 - 6.1e-08 32.3 7.4 0.0018 17.6 0.1 2.6 3 1 0 3 3 3 2 Thiazole biosynthesis protein ThiG NMO PF03060.15 ABK70435.1 - 1.1e-07 31.6 5.6 0.00049 19.6 1.3 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase DHO_dh PF01180.21 ABK70435.1 - 2.9e-06 26.7 0.5 0.04 13.1 0.0 2.5 2 1 0 2 2 2 2 Dihydroorotate dehydrogenase G3P_antiterm PF04309.12 ABK70435.1 - 4.2e-06 26.3 0.7 0.0093 15.4 0.0 2.2 2 0 0 2 2 2 2 Glycerol-3-phosphate responsive antiterminator Dus PF01207.17 ABK70435.1 - 7.4e-06 25.3 0.0 0.018 14.1 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) IMPDH PF00478.25 ABK70435.1 - 0.00011 21.3 3.0 0.022 13.7 0.4 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain TMP-TENI PF02581.17 ABK70435.1 - 0.00013 21.3 0.7 0.34 10.2 0.0 2.4 2 0 0 2 2 2 2 Thiamine monophosphate synthase FMN_dh PF01070.18 ABK70435.1 - 1.9 7.4 12.7 5.7 5.9 0.5 2.8 1 1 2 3 3 3 0 FMN-dependent dehydrogenase adh_short_C2 PF13561.6 ABK70436.1 - 1.7e-53 181.6 5.6 2e-53 181.4 5.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK70436.1 - 3.9e-49 166.8 0.2 5.1e-49 166.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK70436.1 - 1.1e-07 31.9 0.7 2.6e-07 30.7 0.7 1.5 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 ABK70436.1 - 0.2 11.0 0.0 0.28 10.5 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) MarR PF01047.22 ABK70437.1 - 1.4e-15 56.9 1.0 6.3e-14 51.6 0.0 2.1 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.7 ABK70437.1 - 7.7e-10 38.5 0.4 7.7e-10 38.5 0.4 1.9 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 ABK70437.1 - 5e-07 30.1 1.1 9.8e-06 26.0 0.1 2.1 2 0 0 2 2 2 1 Winged helix DNA-binding domain TrmB PF01978.19 ABK70437.1 - 2.2e-06 27.5 0.0 3.7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 ABK70437.1 - 2.3e-05 24.1 0.1 2.3e-05 24.1 0.1 2.9 3 1 0 3 3 3 1 IclR helix-turn-helix domain HTH_24 PF13412.6 ABK70437.1 - 6.2e-05 22.5 0.0 0.0011 18.5 0.0 2.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Rrf2 PF02082.20 ABK70437.1 - 0.0014 18.9 0.8 0.22 11.9 0.0 2.3 2 0 0 2 2 2 1 Transcriptional regulator HTH_6 PF01418.17 ABK70437.1 - 0.0018 18.2 0.0 0.0052 16.7 0.0 1.7 2 1 0 2 2 2 1 Helix-turn-helix domain, rpiR family HTH_Crp_2 PF13545.6 ABK70437.1 - 0.002 18.1 1.7 0.016 15.2 0.1 2.5 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain HTH_45 PF14947.6 ABK70437.1 - 0.0021 18.0 0.0 0.003 17.5 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix Fe_dep_repress PF01325.19 ABK70437.1 - 0.0025 17.9 0.0 0.0049 17.0 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain GntR PF00392.21 ABK70437.1 - 0.0028 17.3 1.4 0.0041 16.7 0.1 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_34 PF13601.6 ABK70437.1 - 0.0064 16.7 0.0 0.01 16.0 0.0 1.4 1 1 0 1 1 1 1 Winged helix DNA-binding domain HxlR PF01638.17 ABK70437.1 - 0.011 15.5 0.1 0.024 14.5 0.0 1.5 1 1 0 1 1 1 0 HxlR-like helix-turn-helix DUF3116 PF11313.8 ABK70437.1 - 0.02 14.8 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3116) TF_AP-2 PF03299.14 ABK70437.1 - 0.027 14.4 0.4 0.038 14.0 0.4 1.3 1 0 0 1 1 1 0 Transcription factor AP-2 HTH_1 PF00126.27 ABK70437.1 - 0.031 14.2 3.2 0.082 12.9 0.6 2.7 2 1 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_AsnC-type PF13404.6 ABK70437.1 - 0.034 14.0 3.4 0.14 12.0 0.1 2.9 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain FtsK_gamma PF09397.10 ABK70437.1 - 0.049 13.4 0.1 0.092 12.6 0.1 1.5 1 0 0 1 1 1 0 Ftsk gamma domain TerB_C PF15615.6 ABK70437.1 - 0.056 13.7 1.4 3.3 8.0 0.2 2.1 2 0 0 2 2 2 0 TerB-C domain HTH_20 PF12840.7 ABK70437.1 - 0.075 13.1 0.2 0.075 13.1 0.2 2.4 3 1 0 3 3 3 0 Helix-turn-helix domain SPOR PF05036.13 ABK70437.1 - 0.11 12.9 0.4 0.34 11.3 0.4 1.9 1 1 0 1 1 1 0 Sporulation related domain Helicase_C_3 PF13625.6 ABK70438.1 - 1.1e-41 141.9 0.4 2.6e-41 140.7 0.4 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain WYL PF13280.6 ABK70438.1 - 0.044 13.8 0.0 0.25 11.4 0.0 2.1 2 0 0 2 2 2 0 WYL domain dCMP_cyt_deam_1 PF00383.23 ABK70439.1 - 2.5e-16 59.4 0.0 3.1e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ABK70439.1 - 2.6e-11 43.4 0.0 3.5e-11 43.0 0.0 1.2 1 1 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 ABK70439.1 - 0.046 13.8 0.0 0.1 12.7 0.0 1.7 1 1 1 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 DUF5642 PF18702.1 ABK70440.1 - 1.4e-65 220.6 5.9 1.4e-65 220.6 5.9 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF5642) DUF3558 PF12079.8 ABK70441.1 - 2.4e-24 86.3 1.0 2.8e-24 86.0 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3558) Fungal_lectin PF07938.12 ABK70441.1 - 0.11 11.9 0.1 0.15 11.5 0.1 1.1 1 0 0 1 1 1 0 Fungal fucose-specific lectin PTS_EIIA_2 PF00359.22 ABK70442.1 - 1.4e-30 106.1 0.0 2.2e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 PTS_IIB PF02302.17 ABK70442.1 - 8.9e-20 71.2 1.8 1.6e-19 70.4 1.8 1.5 1 0 0 1 1 1 1 PTS system, Lactose/Cellobiose specific IIB subunit Aconitase PF00330.20 ABK70442.1 - 0.031 13.3 0.6 0.046 12.7 0.6 1.1 1 0 0 1 1 1 0 Aconitase family (aconitate hydratase) adh_short_C2 PF13561.6 ABK70443.1 - 2.2e-37 128.8 0.9 2.6e-37 128.6 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK70443.1 - 3.8e-34 117.9 0.0 4.4e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK70443.1 - 2.1e-05 24.5 0.5 2.9e-05 24.0 0.5 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK70443.1 - 0.03 13.8 0.5 0.09 12.2 0.5 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 ABK70443.1 - 0.077 12.3 0.0 0.09 12.1 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) LPD7 PF18821.1 ABK70443.1 - 0.11 12.6 0.2 0.71 10.0 0.1 2.2 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 7 Rieske PF00355.26 ABK70445.1 - 5.8e-18 64.6 0.0 7.2e-18 64.3 0.0 1.1 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 ABK70445.1 - 2.1e-07 30.8 0.0 2.4e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Jas PF16135.5 ABK70445.1 - 0.055 13.7 0.3 0.089 13.0 0.3 1.4 1 0 0 1 1 1 0 TPL-binding domain in jasmonate signalling DUF1688 PF07958.11 ABK70446.1 - 3.4e-137 457.6 0.0 3.9e-137 457.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Ala_racemase_N PF01168.20 ABK70447.1 - 2.1e-17 63.5 0.1 2.8e-17 63.1 0.1 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.6 ABK70447.1 - 2.6e-16 60.1 0.0 7.7e-16 58.5 0.0 1.9 1 0 0 1 1 1 1 Putative serine dehydratase domain MaoC_dehydrat_N PF13452.6 ABK70448.1 - 6.4e-23 81.3 0.0 1e-22 80.6 0.0 1.3 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase OB_aCoA_assoc PF01796.17 ABK70448.1 - 6e-21 74.2 1.1 1.4e-20 73.1 1.1 1.7 1 0 0 1 1 1 1 DUF35 OB-fold domain, acyl-CoA-associated MaoC_dehydratas PF01575.19 ABK70448.1 - 0.0095 15.5 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain GP17 PF17420.2 ABK70448.1 - 0.087 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Superinfection exclusion gene product 17 DUF35_N PF12172.8 ABK70448.1 - 0.12 12.2 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) 4HBT PF03061.22 ABK70448.1 - 0.15 12.4 0.0 0.39 11.1 0.0 1.6 1 0 0 1 1 1 0 Thioesterase superfamily Oxidored_FMN PF00724.20 ABK70449.1 - 3.6e-49 167.9 0.0 8.6e-45 153.5 0.0 2.0 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family ECH_1 PF00378.20 ABK70451.1 - 7.4e-44 149.9 0.0 8.9e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK70451.1 - 1.1e-21 77.8 0.1 8.9e-19 68.2 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase SNF2_N PF00176.23 ABK70452.1 - 1.8e-19 69.7 0.0 3.8e-19 68.6 0.0 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 ABK70452.1 - 0.00012 22.1 0.0 0.00021 21.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ABK70452.1 - 0.0013 18.5 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 ABK70452.1 - 0.045 14.0 0.0 0.15 12.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain HHH_5 PF14520.6 ABK70452.1 - 0.11 13.1 0.0 0.35 11.5 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain RsdA_SigD_bd PF16751.5 ABK70453.1 - 1.1e-20 73.6 0.2 2.8e-20 72.3 0.2 1.8 1 0 0 1 1 1 1 Anti-sigma-D factor RsdA to sigma factor binding region DUF4363 PF14276.6 ABK70453.1 - 0.02 15.0 0.3 0.037 14.1 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) Methyltransf_34 PF11312.8 ABK70453.1 - 0.034 13.4 0.1 0.048 12.9 0.1 1.1 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Cytochrom_B562 PF07361.11 ABK70453.1 - 0.24 12.1 0.8 0.41 11.3 0.5 1.5 1 1 0 1 1 1 0 Cytochrome b562 CysG_dimeriser PF10414.9 ABK70453.1 - 0.24 11.1 2.1 4.2 7.2 0.6 2.4 2 0 0 2 2 2 0 Sirohaem synthase dimerisation region DNA_primase_S PF01896.19 ABK70455.1 - 5.5e-06 26.5 0.0 1.6e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 DNA primase small subunit Fe_dep_repr_C PF02742.15 ABK70456.1 - 3.6e-29 100.7 0.0 7.3e-29 99.7 0.0 1.6 1 0 0 1 1 1 1 Iron dependent repressor, metal binding and dimerisation domain Fe_dep_repress PF01325.19 ABK70456.1 - 3e-23 81.8 0.1 1.7e-22 79.4 0.0 2.2 3 0 0 3 3 3 1 Iron dependent repressor, N-terminal DNA binding domain FeoA PF04023.14 ABK70456.1 - 2.5e-09 37.3 0.7 2.5e-09 37.3 0.7 2.7 4 0 0 4 4 4 1 FeoA domain HTH_27 PF13463.6 ABK70456.1 - 1.5e-05 25.4 0.5 0.00014 22.2 0.2 2.6 3 0 0 3 3 3 1 Winged helix DNA-binding domain HTH_24 PF13412.6 ABK70456.1 - 0.0003 20.3 1.0 0.002 17.6 0.0 2.6 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 ABK70456.1 - 0.00032 20.5 0.9 0.00097 19.0 0.1 2.2 3 0 0 3 3 3 1 MarR family HTH_Crp_2 PF13545.6 ABK70456.1 - 0.00041 20.3 0.1 0.0042 17.0 0.1 2.6 2 1 0 2 2 2 1 Crp-like helix-turn-helix domain HemN_C PF06969.16 ABK70456.1 - 0.0028 17.7 0.0 0.0066 16.5 0.0 1.6 1 0 0 1 1 1 1 HemN C-terminal domain MarR PF01047.22 ABK70456.1 - 0.032 14.2 0.0 0.069 13.1 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_1 PF00126.27 ABK70456.1 - 0.04 13.9 0.1 0.13 12.3 0.1 1.9 1 1 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_20 PF12840.7 ABK70456.1 - 0.057 13.5 0.3 0.27 11.3 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Glyco_transf_4 PF13439.6 ABK70457.1 - 6.8e-31 107.5 1.6 6.8e-31 107.5 1.6 1.7 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 ABK70457.1 - 6.8e-30 103.8 0.0 1e-29 103.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ABK70457.1 - 3.7e-25 88.9 0.9 9e-25 87.7 0.9 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 ABK70457.1 - 1.1e-19 71.5 9.7 1.1e-19 71.5 9.7 2.5 1 1 1 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 ABK70457.1 - 9.7e-14 51.5 0.1 4.4e-13 49.4 0.1 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 ABK70457.1 - 3.7e-09 36.7 0.9 2.8e-06 27.2 0.1 2.4 1 1 1 2 2 2 2 Starch synthase catalytic domain GGDEF_2 PF17853.1 ABK70457.1 - 0.07 13.4 0.8 0.27 11.5 0.3 2.2 2 1 0 2 2 2 0 GGDEF-like domain MscL PF01741.18 ABK70458.1 - 1.7e-34 118.7 0.2 2e-34 118.5 0.2 1.0 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL Vpu PF00558.19 ABK70458.1 - 0.021 14.6 0.0 0.065 13.0 0.0 1.7 2 0 0 2 2 2 0 Vpu protein TrpP PF17099.5 ABK70458.1 - 0.027 14.2 0.2 0.79 9.5 0.0 2.1 2 0 0 2 2 2 0 Tryptophan transporter TrpP DUF4330 PF14221.6 ABK70458.1 - 0.22 11.7 1.2 8.4 6.6 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4330) T7SS_ESX_EspC PF10824.8 ABK70459.1 - 1.2e-08 35.3 0.4 1.2e-08 35.3 0.4 1.9 2 0 0 2 2 2 1 Excreted virulence factor EspC, type VII ESX diderm Glyco_hydro_16 PF00722.21 ABK70460.1 - 1e-12 47.9 0.3 1.4e-12 47.5 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Ribosom_S30AE_C PF16321.5 ABK70463.1 - 1.8e-29 101.2 0.0 9.3e-17 60.5 0.0 2.4 2 0 0 2 2 2 2 Sigma 54 modulation/S30EA ribosomal protein C terminus Ribosomal_S30AE PF02482.19 ABK70463.1 - 1.4e-05 25.8 0.0 2.1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein OrfB_IS605 PF01385.19 ABK70463.1 - 0.23 11.7 2.1 2 8.7 0.1 2.1 2 0 0 2 2 2 0 Probable transposase Acetyltransf_1 PF00583.25 ABK70464.1 - 8.8e-11 42.1 0.0 1.5e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 ABK70464.1 - 7e-08 32.3 0.1 1.4e-07 31.4 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 ABK70464.1 - 3.9e-06 27.2 0.0 6.3e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ABK70464.1 - 1.9e-05 25.4 0.0 6.1e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ABK70464.1 - 0.00013 21.9 0.0 0.00019 21.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ABK70464.1 - 0.0011 19.1 0.0 0.0021 18.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 ABK70464.1 - 0.0039 16.9 0.4 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 ABK70464.1 - 0.039 13.5 0.1 0.056 13.0 0.1 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase TetR_N PF00440.23 ABK70466.1 - 7.4e-13 48.1 0.1 1.7e-12 46.9 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_10 PF04967.12 ABK70466.1 - 0.1 12.4 0.0 0.3 10.9 0.0 1.9 1 1 0 1 1 1 0 HTH DNA binding domain HTH_Tnp_1_2 PF13022.6 ABK70466.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix of insertion element transposase DUF5318 PF17249.2 ABK70467.1 - 7.2e-64 213.5 0.3 1e-63 213.0 0.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5318) DUF4451 PF14616.6 ABK70467.1 - 0.024 14.8 0.1 0.079 13.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4451) Prok-RING_4 PF14447.6 ABK70467.1 - 0.12 12.3 2.2 0.5 10.3 0.1 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Amidohydro_2 PF04909.14 ABK70468.1 - 1.5e-27 97.2 1.2 1.7e-27 97.0 1.2 1.2 1 0 0 1 1 1 1 Amidohydrolase Peptidase_M19 PF01244.21 ABK70468.1 - 0.001 18.3 0.0 0.0015 17.8 0.0 1.2 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) DUF1769 PF08588.10 ABK70469.1 - 0.18 12.0 0.9 22 5.4 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1769) PASTA PF03793.19 ABK70470.1 - 0.0036 17.1 0.0 0.047 13.6 0.0 2.2 1 1 0 1 1 1 1 PASTA domain CBM_48 PF02922.18 ABK70471.1 - 4.4e-25 87.8 0.1 1.6e-20 73.2 0.0 2.6 2 0 0 2 2 2 2 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase_C PF02806.18 ABK70471.1 - 4.3e-22 78.4 0.0 8.1e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 ABK70471.1 - 2.1e-13 50.6 0.0 1.9e-07 31.0 0.0 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 ABK70471.1 - 0.0017 16.6 0.1 0.0077 14.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 70 PPK2 PF03976.14 ABK70472.1 - 2.1e-103 344.8 3.1 2.4e-103 344.6 3.1 1.0 1 0 0 1 1 1 1 Polyphosphate kinase 2 (PPK2) MeaB PF03308.16 ABK70472.1 - 0.062 12.3 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Ribonuc_L-PSP PF01042.21 ABK70473.1 - 7e-15 55.1 0.0 9.9e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP YjgF_endoribonc PF14588.6 ABK70473.1 - 1.3e-12 48.1 0.3 1.7e-12 47.7 0.3 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease NAD_binding_2 PF03446.15 ABK70474.1 - 2.4e-50 170.8 2.1 4e-50 170.1 2.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ABK70474.1 - 2.1e-36 124.9 1.9 3.7e-36 124.0 1.9 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 ABK70474.1 - 6e-09 36.4 1.5 9.3e-09 35.8 0.2 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 ABK70474.1 - 3.1e-05 23.4 0.4 8.9e-05 21.9 0.0 1.9 2 1 1 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 ABK70474.1 - 5.6e-05 22.8 0.8 0.00012 21.7 0.2 1.8 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 ABK70474.1 - 0.00034 20.3 0.0 0.00065 19.4 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 ABK70474.1 - 0.0036 17.2 0.3 0.0036 17.2 0.3 2.3 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PDH PF02153.17 ABK70474.1 - 0.072 12.1 0.3 0.11 11.5 0.3 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase TetR_N PF00440.23 ABK70475.1 - 1.9e-12 46.8 0.4 3.9e-12 45.8 0.4 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_29 PF17938.1 ABK70475.1 - 0.037 14.1 0.0 0.088 12.9 0.0 1.9 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain GSDH PF07995.11 ABK70476.1 - 2.1e-15 56.9 0.0 2.7e-14 53.2 0.0 2.1 2 1 0 2 2 2 1 Glucose / Sorbosone dehydrogenase NHL PF01436.21 ABK70476.1 - 0.15 12.2 0.0 0.58 10.3 0.0 2.1 2 0 0 2 2 2 0 NHL repeat Big_10 PF17964.1 ABK70477.1 - 1e-60 204.8 0.7 1.5e-60 204.3 0.7 1.2 1 0 0 1 1 1 1 Bacterial Ig domain YkuD PF03734.14 ABK70477.1 - 4.8e-07 30.3 0.0 8.5e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain TAT_signal PF10518.9 ABK70477.1 - 0.25 11.2 5.7 0.53 10.2 5.7 1.6 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence tRNA_SAD PF07973.14 ABK70478.1 - 0.0065 16.6 0.0 0.0076 16.3 0.0 1.2 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain EamA PF00892.20 ABK70479.1 - 1.5e-19 70.5 30.1 9.2e-10 38.8 8.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 ABK70479.1 - 0.0018 17.6 2.7 0.0019 17.5 0.6 2.0 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport TetR_C_24 PF17932.1 ABK70480.1 - 7.2e-30 103.6 0.1 9.9e-30 103.1 0.1 1.2 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK70480.1 - 1.1e-11 44.4 0.7 3.1e-11 42.9 0.4 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_27 PF17935.1 ABK70480.1 - 0.0012 18.9 0.1 0.0018 18.3 0.1 1.2 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_33 PF13305.6 ABK70480.1 - 0.0077 17.0 0.3 0.012 16.3 0.3 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain LPD39 PF18858.1 ABK70480.1 - 0.017 15.2 1.0 0.023 14.8 1.0 1.1 1 0 0 1 1 1 0 Large polyvalent protein associated domain 39 SnoaL_2 PF12680.7 ABK70481.1 - 6.4e-08 33.2 4.1 2.5e-07 31.3 1.0 2.4 2 1 0 2 2 2 1 SnoaL-like domain NTF2 PF02136.20 ABK70481.1 - 1.8e-06 28.5 0.0 2.6e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4632 PF15451.6 ABK70481.1 - 0.01 15.9 0.2 2.2 8.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) DUF3558 PF12079.8 ABK70482.1 - 1.1e-31 110.2 0.5 1.2e-31 110.0 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3558) Rho_N PF07498.12 ABK70483.1 - 2.3e-06 27.4 0.1 6.7e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Rho termination factor, N-terminal domain Ish1 PF10281.9 ABK70483.1 - 0.013 15.8 0.2 0.054 13.8 0.1 2.0 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein SAP PF02037.27 ABK70483.1 - 0.025 14.4 0.1 0.11 12.3 0.0 2.1 3 0 0 3 3 3 0 SAP domain Ribosomal_S4 PF00163.19 ABK70484.1 - 4.9e-30 104.3 3.1 1e-29 103.3 3.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 ABK70484.1 - 2.3e-19 68.8 0.3 4e-19 68.0 0.3 1.4 1 0 0 1 1 1 1 S4 domain CN_hydrolase PF00795.22 ABK70485.1 - 7.9e-30 104.1 0.0 1.1e-29 103.6 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Reovirus_M2 PF05993.12 ABK70485.1 - 0.057 11.5 0.0 0.074 11.1 0.0 1.1 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) Epimerase PF01370.21 ABK70486.1 - 4.3e-25 88.6 0.1 2.1e-24 86.3 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ABK70486.1 - 1.8e-20 73.2 0.3 2.6e-20 72.7 0.3 1.3 1 1 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 ABK70486.1 - 4.2e-18 65.8 0.0 5.9e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 ABK70486.1 - 4.3e-13 49.5 3.1 4.3e-13 49.5 3.1 1.5 1 1 1 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ABK70486.1 - 1.2e-10 40.9 0.0 1.7e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ABK70486.1 - 2.4e-08 33.5 0.6 8.7e-08 31.6 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 ABK70486.1 - 4.9e-06 25.9 0.3 0.0011 18.2 0.3 2.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 ABK70486.1 - 0.0019 17.7 0.4 0.0042 16.6 0.4 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK70486.1 - 0.0022 18.0 0.2 0.0057 16.6 0.2 1.7 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 ABK70486.1 - 0.0098 15.5 0.2 0.016 14.8 0.2 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ribosomal_L23 PF00276.20 ABK70487.1 - 1.1e-31 109.0 0.6 1.2e-31 108.9 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L23 TetR_N PF00440.23 ABK70488.1 - 3.3e-15 55.6 0.1 3.3e-15 55.6 0.1 2.2 3 0 0 3 3 3 1 Bacterial regulatory proteins, tetR family LacI PF00356.21 ABK70488.1 - 0.00089 19.0 0.1 0.0021 17.8 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family HTH_7 PF02796.15 ABK70488.1 - 0.0044 17.1 0.1 0.0086 16.1 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_31 PF13560.6 ABK70488.1 - 0.023 15.1 0.9 0.096 13.0 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 ABK70488.1 - 0.027 14.3 0.4 0.11 12.3 0.4 2.1 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_17 PF12728.7 ABK70488.1 - 0.038 14.2 0.0 0.089 13.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain TetR_C_35 PF18556.1 ABK70488.1 - 0.041 14.0 0.2 0.093 12.9 0.1 1.7 2 0 0 2 2 2 0 Bacterial Tetracyclin repressor, C-terminal domain HTH_38 PF13936.6 ABK70488.1 - 0.055 13.2 0.8 0.11 12.3 0.2 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_22 PF13309.6 ABK70488.1 - 0.072 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 HTH domain HTH_23 PF13384.6 ABK70488.1 - 0.087 12.7 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 ABK70488.1 - 0.089 12.2 0.3 0.26 10.7 0.3 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_3 PF01381.22 ABK70488.1 - 0.13 12.4 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix BPD_transp_1 PF00528.22 ABK70489.1 - 2e-16 60.3 16.7 2e-16 60.3 16.7 2.3 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component OpcA_G6PD_assem PF10128.9 ABK70490.1 - 4.4e-82 275.4 1.3 5.3e-82 275.1 1.3 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase subunit ABC_tran PF00005.27 ABK70491.1 - 1.9e-34 119.1 0.0 2.4e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK70491.1 - 4.5e-13 49.7 0.0 4.7e-06 26.6 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK70491.1 - 5.7e-11 42.3 0.0 1.5e-10 40.9 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ABK70491.1 - 8e-05 22.3 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 ABK70491.1 - 0.00055 19.7 0.0 0.0098 15.6 0.0 2.0 1 1 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 ABK70491.1 - 0.00055 20.4 0.1 0.00083 19.8 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 ABK70491.1 - 0.00056 20.1 0.1 0.0016 18.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 ABK70491.1 - 0.0025 18.3 0.0 0.0042 17.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 ABK70491.1 - 0.003 16.4 0.0 0.73 8.6 0.0 3.0 2 1 0 2 2 2 1 Predicted ATPase of the ABC class APS_kinase PF01583.20 ABK70491.1 - 0.0031 17.4 0.0 0.0072 16.2 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase RsgA_GTPase PF03193.16 ABK70491.1 - 0.0035 17.2 0.0 0.0062 16.5 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_24 PF13479.6 ABK70491.1 - 0.023 14.4 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 ABK70491.1 - 0.024 14.9 0.1 0.039 14.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ABK70491.1 - 0.029 14.1 0.0 0.071 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ABK70491.1 - 0.03 13.9 0.0 0.062 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ABK70491.1 - 0.035 14.0 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 ABK70491.1 - 0.042 13.9 0.0 0.13 12.2 0.0 1.9 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 ABK70491.1 - 0.1 12.9 0.1 1.1 9.5 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 ABK70491.1 - 0.1 13.1 0.0 0.17 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 ABK70491.1 - 0.11 11.1 0.0 0.68 8.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 ABK70491.1 - 0.16 11.7 0.0 0.37 10.5 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein ATP-synt_ab PF00006.25 ABK70491.1 - 0.17 11.5 0.0 0.38 10.4 0.0 1.6 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain TsaE PF02367.17 ABK70491.1 - 0.2 11.6 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DDE_Tnp_1_4 PF13701.6 ABK70492.1 - 1.3e-34 119.3 0.0 1.8e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain group 1 DDE_Tnp_1 PF01609.21 ABK70492.1 - 0.00052 19.7 0.0 0.0031 17.2 0.0 1.9 1 1 0 1 1 1 1 Transposase DDE domain Sugar_tr PF00083.24 ABK70493.1 - 1.8e-60 205.1 16.0 2.4e-60 204.7 16.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ABK70493.1 - 2.2e-42 145.3 58.3 4.8e-39 134.3 30.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 ABK70493.1 - 1.8 6.7 11.3 0.39 9.0 2.1 3.0 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 ABK70493.1 - 2 7.2 16.7 0.03 13.2 4.1 2.5 2 1 0 2 2 2 0 MFS_1 like family VWA_2 PF13519.6 ABK70494.1 - 1e-07 32.5 0.3 1.9e-06 28.5 0.0 3.2 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 ABK70494.1 - 0.00035 20.5 0.7 0.047 13.6 0.0 4.3 2 2 1 3 3 3 1 von Willebrand factor type A domain TipAS PF07739.13 ABK70494.1 - 0.004 17.7 4.9 0.0048 17.4 2.1 2.5 2 1 0 2 2 2 1 TipAS antibiotic-recognition domain VWA PF00092.28 ABK70494.1 - 0.006 16.8 0.0 0.037 14.3 0.0 2.3 1 1 0 1 1 1 1 von Willebrand factor type A domain ATLF PF07737.11 ABK70494.1 - 0.048 12.9 0.2 0.08 12.2 0.2 1.2 1 0 0 1 1 1 0 Anthrax toxin lethal factor, N- and C-terminal domain CdiI_2 PF18593.1 ABK70494.1 - 0.13 12.9 2.8 0.19 12.4 0.4 2.6 2 0 0 2 2 2 0 CdiI immunity protein Atg14 PF10186.9 ABK70494.1 - 0.23 10.5 1.3 0.29 10.2 0.1 1.6 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 PAPA-1 PF04795.12 ABK70494.1 - 6.9 7.5 8.8 0.73 10.7 3.9 2.0 2 1 0 2 2 2 0 PAPA-1-like conserved region DUF3099 PF11298.8 ABK70495.1 - 8e-28 96.4 3.6 1.1e-27 96.0 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3099) Voltage_CLC PF00654.20 ABK70496.1 - 9e-84 281.7 35.3 9e-84 281.7 35.3 2.0 2 0 0 2 2 2 2 Voltage gated chloride channel MauJ PF17419.2 ABK70497.1 - 0.014 14.8 0.1 0.019 14.4 0.1 1.3 1 1 0 1 1 1 0 Methylamine utilization protein MauJ WG_beta_rep PF14903.6 ABK70497.1 - 0.12 12.7 0.3 3.6 7.9 0.0 2.3 2 0 0 2 2 2 0 WG containing repeat Trp_oprn_chp PF09534.10 ABK70498.1 - 1.3e-49 168.4 29.6 1.5e-49 168.3 29.6 1.0 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) AurF PF11583.8 ABK70499.1 - 5.9e-99 330.9 0.3 7.4e-99 330.6 0.3 1.1 1 0 0 1 1 1 1 P-aminobenzoate N-oxygenase AurF DUF4873 PF16170.5 ABK70499.1 - 8.6e-25 86.8 0.1 1.6e-24 86.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4873) DUF5313 PF17240.2 ABK70500.1 - 4.6e-55 185.3 0.4 5.2e-55 185.1 0.4 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5313) PAS_6 PF08348.11 ABK70501.1 - 4.1e-28 97.6 0.0 6.9e-28 96.8 0.0 1.4 1 0 0 1 1 1 1 YheO-like PAS domain Aminotran_5 PF00266.19 ABK70501.1 - 6.4e-27 94.5 0.0 1e-26 93.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V HTH_22 PF13309.6 ABK70501.1 - 2.6e-21 75.5 0.0 5.6e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 HTH domain HTH_23 PF13384.6 ABK70501.1 - 0.0016 18.2 0.0 0.0057 16.4 0.0 2.0 1 0 0 1 1 1 1 Homeodomain-like domain DUF993 PF06187.11 ABK70503.1 - 5.3e-184 611.5 0.0 6.1e-184 611.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF993) Bac_luciferase PF00296.20 ABK70504.1 - 2.4e-50 171.8 0.2 6.3e-50 170.4 0.1 1.5 2 0 0 2 2 2 1 Luciferase-like monooxygenase SseB PF07179.12 ABK70505.1 - 8.8e-23 80.9 0.0 4e-12 46.5 0.0 2.1 2 0 0 2 2 2 2 SseB protein N-terminal domain MafB19-deam PF14437.6 ABK70506.1 - 2.3e-21 76.0 0.0 2.6e-21 75.8 0.0 1.0 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 ABK70506.1 - 3.6e-21 74.9 0.0 4.7e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.6 ABK70506.1 - 0.0084 16.2 3.0 0.055 13.5 3.0 2.0 1 1 0 1 1 1 1 Bd3614-like deaminase APOBEC3 PF18771.1 ABK70506.1 - 0.14 12.2 0.0 0.29 11.3 0.0 1.4 2 0 0 2 2 2 0 APOBEC3 adh_short_C2 PF13561.6 ABK70507.1 - 9.2e-52 175.9 2.9 4.3e-51 173.7 2.9 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK70507.1 - 1.2e-48 165.2 1.0 5.9e-48 162.9 1.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK70507.1 - 8.9e-15 55.1 0.5 1.7e-14 54.2 0.6 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK70507.1 - 0.027 14.0 0.6 0.1 12.0 0.6 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sugar_tr PF00083.24 ABK70508.1 - 2.2e-95 320.2 11.0 2.6e-95 320.0 11.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ABK70508.1 - 1.6e-37 129.3 50.4 1.8e-34 119.2 22.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PASTA PF03793.19 ABK70508.1 - 0.099 12.5 0.0 0.33 10.8 0.0 1.9 1 0 0 1 1 1 0 PASTA domain PIRT PF15099.6 ABK70508.1 - 1.5 8.4 4.9 0.49 10.0 0.3 2.5 2 1 0 2 2 2 0 Phosphoinositide-interacting protein family ABC2_membrane PF01061.24 ABK70509.1 - 1.4e-12 47.5 12.1 1.9e-12 47.1 12.1 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 ABK70509.1 - 1.6e-09 37.4 13.7 1.6e-09 37.4 13.7 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein NMT1_3 PF16868.5 ABK70510.1 - 1e-73 248.3 1.4 1.2e-73 248.1 1.4 1.0 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 ABK70510.1 - 1e-11 45.2 0.1 1.6e-11 44.6 0.1 1.3 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 ABK70510.1 - 1.3e-08 34.7 0.6 1.8e-08 34.3 0.6 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein HCMV_UL124 PF17609.2 ABK70510.1 - 0.28 11.4 2.6 0.63 10.2 0.7 2.2 2 0 0 2 2 2 0 Family of unknown function Mycobact_memb PF05423.13 ABK70511.1 - 1.5e-06 28.2 0.1 1.5e-06 28.2 0.1 2.0 1 1 1 2 2 2 1 Mycobacterium membrane protein HPTransfase PF10090.9 ABK70511.1 - 0.013 15.3 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphotransferase C-terminal domain Pex14_N PF04695.13 ABK70511.1 - 0.055 14.1 3.2 0.075 13.7 3.2 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PNP_UDP_1 PF01048.20 ABK70512.1 - 3.1e-37 128.1 0.2 3.5e-37 127.9 0.2 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily SBP_bac_1 PF01547.25 ABK70513.1 - 1.1e-32 114.2 10.7 1.6e-32 113.7 7.4 2.0 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 ABK70513.1 - 1.2e-28 100.8 4.7 1.7e-28 100.2 4.7 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Bac_luciferase PF00296.20 ABK70514.1 - 7.1e-31 107.8 11.6 1e-29 104.0 9.3 2.1 1 1 1 2 2 2 2 Luciferase-like monooxygenase Aldedh PF00171.22 ABK70515.1 - 1e-50 172.6 0.1 3e-50 171.1 0.1 1.6 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Methyltransf_3 PF01596.17 ABK70516.1 - 5.8e-26 91.0 0.0 6.6e-26 90.8 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 ABK70516.1 - 1.1e-14 55.3 0.0 2.4e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABK70516.1 - 1.7e-07 31.8 0.2 5.1e-07 30.3 0.0 1.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABK70516.1 - 2.5e-06 28.0 0.0 6.5e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABK70516.1 - 6.1e-06 26.1 0.0 9.2e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ABK70516.1 - 0.0031 17.1 0.0 0.0065 16.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 ABK70516.1 - 0.021 14.6 0.1 0.031 14.0 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14 PF08704.10 ABK70516.1 - 0.047 13.3 0.0 0.061 13.0 0.0 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit GidB PF02527.15 ABK70516.1 - 0.052 12.9 0.2 0.63 9.3 0.1 2.2 1 1 1 2 2 2 0 rRNA small subunit methyltransferase G Ubie_methyltran PF01209.18 ABK70516.1 - 0.075 12.4 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Dala_Dala_lig_C PF07478.13 ABK70518.1 - 1.1e-66 224.2 0.0 1.4e-66 223.9 0.0 1.1 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 ABK70518.1 - 6.5e-31 106.9 0.0 1e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase N-terminus ATP-grasp PF02222.22 ABK70518.1 - 1.3e-06 28.1 0.0 0.00012 21.7 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 ABK70518.1 - 7.5e-06 26.1 0.0 0.0044 17.1 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 ABK70518.1 - 0.00028 20.5 0.0 0.0049 16.5 0.0 2.0 2 0 0 2 2 2 1 RimK-like ATP-grasp domain CPSase_L_D2 PF02786.17 ABK70518.1 - 0.0017 17.9 0.0 0.022 14.3 0.0 2.1 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 ABK70518.1 - 0.0044 16.6 0.0 0.043 13.4 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_ST PF14397.6 ABK70518.1 - 0.0088 15.3 0.0 0.1 11.8 0.0 2.0 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp DUF1707 PF08044.11 ABK70519.1 - 4.2e-20 71.5 5.1 7.3e-20 70.8 5.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1707) DUF2154 PF09922.9 ABK70519.1 - 0.00058 19.7 0.0 0.001 18.9 0.0 1.4 1 1 0 1 1 1 1 Cell wall-active antibiotics response 4TMS YvqF DUF1176 PF06674.11 ABK70519.1 - 0.11 11.9 0.1 0.14 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) MCPVI PF02993.14 ABK70520.1 - 0.0071 16.2 0.1 0.0089 15.9 0.1 1.2 1 0 0 1 1 1 1 Minor capsid protein VI Herpes_UL42 PF02282.16 ABK70520.1 - 0.064 13.1 0.1 0.12 12.3 0.0 1.4 2 0 0 2 2 2 0 DNA polymerase processivity factor (UL42) DUF2516 PF10724.9 ABK70523.1 - 1.2e-26 92.7 3.9 1.4e-26 92.6 3.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2516) DUF420 PF04238.12 ABK70523.1 - 0.04 14.2 3.7 0.057 13.7 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF420) CoxIIa PF08113.11 ABK70523.1 - 0.09 12.6 3.6 0.21 11.4 3.6 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IIa family Tetraspanin PF00335.20 ABK70523.1 - 0.3 10.7 3.6 0.37 10.5 3.6 1.2 1 0 0 1 1 1 0 Tetraspanin family DUF2206 PF09971.9 ABK70523.1 - 0.34 9.6 1.3 0.42 9.3 1.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) S1FA PF04689.13 ABK70523.1 - 3.7 7.8 5.8 2 8.6 1.0 2.1 2 0 0 2 2 2 0 DNA binding protein S1FA PsbJ PF01788.17 ABK70523.1 - 4.4 7.3 8.9 7.5 6.5 3.5 2.2 2 0 0 2 2 2 0 PsbJ PRA1 PF03208.19 ABK70523.1 - 5.6 6.6 8.1 17 5.1 8.1 1.7 1 1 0 1 1 1 0 PRA1 family protein DUF222 PF02720.17 ABK70524.1 - 4.5e-51 174.1 11.3 1e-50 172.9 11.3 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF222) HNH PF01844.23 ABK70524.1 - 1.6e-05 25.0 1.7 2.6e-05 24.3 1.7 1.3 1 0 0 1 1 1 1 HNH endonuclease HNH_2 PF13391.6 ABK70524.1 - 0.0058 16.7 2.3 0.039 14.1 2.3 2.3 1 1 0 1 1 1 1 HNH endonuclease ABM PF03992.16 ABK70526.1 - 2e-19 69.4 0.1 2.6e-19 69.1 0.1 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Dabb PF07876.12 ABK70526.1 - 0.09 13.4 0.0 0.11 13.2 0.0 1.1 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain MLTR_LBD PF17765.1 ABK70528.1 - 1.7e-50 171.4 0.9 1.7e-50 171.4 0.9 1.6 2 0 0 2 2 2 1 MmyB-like transcription regulator ligand binding domain HTH_31 PF13560.6 ABK70528.1 - 2.1e-16 60.0 7.8 1e-15 57.8 7.8 2.3 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 ABK70528.1 - 0.094 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix TPR_14 PF13428.6 ABK70528.1 - 1.1 10.3 4.4 1.8 9.6 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat ketoacyl-synt PF00109.26 ABK70529.1 - 1.7e-88 296.5 0.1 5.9e-88 294.7 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 ABK70529.1 - 4.3e-62 209.2 0.3 1.5e-61 207.5 0.1 2.1 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 ABK70529.1 - 6.8e-61 206.5 0.4 1e-60 206.0 0.4 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 ABK70529.1 - 1.3e-59 201.9 1.9 2.6e-59 200.9 1.9 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 ABK70529.1 - 1.1e-42 144.7 1.4 2.7e-42 143.5 1.4 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 ABK70529.1 - 1e-19 71.0 0.0 2.2e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 ABK70529.1 - 2.1e-12 47.2 0.7 9.6e-12 45.1 0.5 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 ABK70529.1 - 5.5e-09 35.8 0.6 1e-07 31.6 0.2 2.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain adh_short PF00106.25 ABK70529.1 - 1.5e-06 27.8 0.5 0.00015 21.3 0.2 3.4 2 1 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.21 ABK70529.1 - 0.0013 18.3 0.3 0.013 15.0 0.1 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family ApbA PF02558.16 ABK70529.1 - 0.0081 15.8 0.2 0.05 13.2 0.1 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 ABK70529.1 - 0.034 13.5 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 ThiF family Polysacc_synt_2 PF02719.15 ABK70529.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 ABK70529.1 - 0.12 12.7 0.1 1.1 9.6 0.1 2.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 ABK70529.1 - 0.19 11.8 0.0 0.63 10.1 0.0 1.8 2 0 0 2 2 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.6 ABK70529.1 - 0.49 10.7 2.6 20 5.5 0.1 3.4 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain CMD PF02627.20 ABK70531.1 - 1.2e-07 31.7 0.0 2.7e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family DUF2384 PF09722.10 ABK70532.1 - 0.12 12.5 0.1 0.12 12.5 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2384) GPDPase_memb PF10110.9 ABK70533.1 - 0.00099 18.0 4.2 0.00099 18.0 4.2 2.8 1 1 3 4 4 4 1 Membrane domain of glycerophosphoryl diester phosphodiesterase Bac_export_2 PF01312.19 ABK70533.1 - 1.5 8.0 23.0 0.029 13.6 6.3 2.0 1 1 1 2 2 2 0 FlhB HrpN YscU SpaS Family DLH PF01738.18 ABK70534.1 - 3.8e-06 26.6 0.1 5.4e-05 22.9 0.1 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 ABK70534.1 - 2.1e-05 24.3 0.1 0.065 12.9 0.2 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ABK70534.1 - 0.00019 20.8 0.6 0.82 8.9 0.6 2.8 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 ABK70534.1 - 0.0003 20.6 0.0 0.00052 19.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 ABK70534.1 - 0.048 14.3 11.3 0.091 13.4 9.6 2.2 1 1 1 2 2 2 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ABK70534.1 - 0.052 13.0 0.2 0.24 10.8 0.2 2.0 3 0 0 3 3 3 0 Prolyl oligopeptidase family RDD PF06271.12 ABK70536.1 - 2.3e-14 53.8 13.3 2.3e-14 53.8 13.3 1.7 2 0 0 2 2 2 1 RDD family CbtB PF09489.10 ABK70536.1 - 0.011 15.9 0.6 0.011 15.9 0.6 2.5 2 1 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) Spore_YhaL PF14147.6 ABK70536.1 - 1.4 8.7 2.9 12 5.7 1.9 2.2 2 0 0 2 2 2 0 Sporulation protein YhaL CMAS PF02353.20 ABK70537.1 - 2.5e-107 358.3 0.0 2.8e-107 358.1 0.0 1.0 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 ABK70537.1 - 3.4e-09 37.3 0.0 7.6e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABK70537.1 - 4.9e-09 36.2 0.0 7.4e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABK70537.1 - 2.4e-08 34.5 0.0 4.5e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK70537.1 - 1.1e-07 32.4 0.0 2.1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABK70537.1 - 0.00016 21.5 0.0 0.00022 21.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ABK70537.1 - 0.041 13.6 0.0 0.063 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 ABK70537.1 - 0.073 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 ABK70537.1 - 0.093 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase MetW PF07021.12 ABK70537.1 - 0.11 12.0 0.0 0.26 10.9 0.0 1.6 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Rick_17kDa_Anti PF05433.15 ABK70538.1 - 0.039 13.8 0.7 0.039 13.8 0.7 2.1 2 0 0 2 2 2 0 Glycine zipper 2TM domain HSP70 PF00012.20 ABK70539.1 - 5.7e-17 61.1 0.0 9.3e-17 60.4 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ABK70539.1 - 1.9e-05 23.7 0.0 5e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 MreB/Mbl protein Citrate_bind PF16114.5 ABK70539.1 - 0.078 12.5 1.9 0.09 12.3 0.2 1.9 2 0 0 2 2 2 0 ATP citrate lyase citrate-binding HTH_20 PF12840.7 ABK70540.1 - 6.2e-12 45.4 0.2 9.4e-12 44.8 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 ABK70540.1 - 1.1e-08 34.9 1.0 1.3e-08 34.6 0.2 1.6 2 0 0 2 2 2 1 MarR family HTH_5 PF01022.20 ABK70540.1 - 1.4e-08 34.4 0.0 2e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 ABK70540.1 - 3.7e-07 29.6 0.0 6e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 ABK70540.1 - 1.3e-06 28.2 0.0 2.1e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 MarR family PaaX PF07848.12 ABK70540.1 - 3.9e-06 27.0 0.1 5.3e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 PaaX-like protein HTH_Crp_2 PF13545.6 ABK70540.1 - 0.00065 19.6 0.2 0.001 19.0 0.2 1.4 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain Rrf2 PF02082.20 ABK70540.1 - 0.00083 19.7 0.0 0.0012 19.2 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator Penicillinase_R PF03965.16 ABK70540.1 - 0.0013 19.1 0.0 0.0017 18.7 0.0 1.1 1 0 0 1 1 1 1 Penicillinase repressor TrmB PF01978.19 ABK70540.1 - 0.0041 17.0 0.0 0.0052 16.7 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_36 PF13730.6 ABK70540.1 - 0.0049 16.8 0.0 0.0061 16.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 ABK70540.1 - 0.0083 16.0 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 HTH domain HTH_IclR PF09339.10 ABK70540.1 - 0.01 15.6 0.1 0.019 14.8 0.1 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain Fe_dep_repress PF01325.19 ABK70540.1 - 0.036 14.3 0.0 0.057 13.6 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain GntR PF00392.21 ABK70540.1 - 0.043 13.5 0.6 0.092 12.4 0.3 1.7 2 1 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_27 PF13463.6 ABK70540.1 - 0.059 13.9 0.0 0.084 13.4 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain Ribosomal_S14 PF00253.21 ABK70541.1 - 1.3e-25 88.9 2.2 1.5e-25 88.7 2.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Sgf11 PF08209.11 ABK70541.1 - 0.011 15.3 2.3 1.3 8.7 0.5 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) DUF2797 PF10977.8 ABK70541.1 - 0.043 13.7 0.3 0.047 13.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) AAA_lid_5 PF17865.1 ABK70541.1 - 0.079 13.0 0.0 0.079 13.0 0.0 1.2 1 0 0 1 1 1 0 Midasin AAA lid domain zf_C2H2_13 PF18508.1 ABK70541.1 - 0.15 11.6 0.7 0.15 11.6 0.7 1.6 1 1 0 1 1 1 0 Zinc finger domain adh_short_C2 PF13561.6 ABK70542.1 - 3e-54 184.1 2.5 3.8e-54 183.7 2.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK70542.1 - 7.1e-46 156.1 0.6 1e-45 155.6 0.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK70542.1 - 3.4e-08 33.6 6.1 3e-07 30.5 6.1 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK70542.1 - 2.8e-07 30.3 0.1 5.7e-07 29.2 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 ABK70542.1 - 0.045 13.1 0.0 0.061 12.7 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) TetR_N PF00440.23 ABK70543.1 - 9.9e-17 60.5 0.0 2.3e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family CobS PF02654.15 ABK70544.1 - 1.2e-44 153.0 28.4 1.3e-44 152.8 28.4 1.0 1 0 0 1 1 1 1 Cobalamin-5-phosphate synthase PigN PF04987.14 ABK70544.1 - 0.44 9.4 3.0 0.56 9.0 3.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) MlaD PF02470.20 ABK70545.1 - 3.7e-14 52.8 0.0 9.1e-14 51.5 0.0 1.7 1 0 0 1 1 1 1 MlaD protein Mce4_CUP1 PF11887.8 ABK70545.1 - 3.7e-05 23.3 2.9 5.7e-05 22.7 2.9 1.3 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative NPV_P10 PF05531.12 ABK70545.1 - 0.0018 18.7 3.8 0.0071 16.8 1.4 2.4 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein HsbA PF12296.8 ABK70545.1 - 0.023 15.1 2.6 0.081 13.4 1.1 2.3 1 1 1 2 2 2 0 Hydrophobic surface binding protein A Baculo_PEP_C PF04513.12 ABK70545.1 - 0.025 14.6 8.2 0.089 12.8 3.0 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Telomere_reg-2 PF10193.9 ABK70545.1 - 0.082 13.4 0.1 0.15 12.5 0.1 1.3 1 0 0 1 1 1 0 Telomere length regulation protein Leu_zip PF15294.6 ABK70545.1 - 0.14 11.7 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 Leucine zipper Vps5 PF09325.10 ABK70545.1 - 0.2 11.2 0.7 0.35 10.4 0.5 1.4 1 1 0 1 1 1 0 Vps5 C terminal like DUF948 PF06103.11 ABK70545.1 - 0.22 11.8 5.1 1.4 9.2 0.8 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) TetR_N PF00440.23 ABK70546.1 - 2e-07 30.7 0.0 4.6e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_29 PF17938.1 ABK70546.1 - 0.056 13.5 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain adh_short PF00106.25 ABK70547.1 - 1.1e-24 87.0 0.0 6.9e-24 84.4 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK70547.1 - 7.2e-18 65.0 0.2 1.5e-17 64.0 0.2 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK70547.1 - 2.9e-07 30.6 0.4 5.3e-07 29.7 0.4 1.4 1 0 0 1 1 1 1 KR domain Dimer_Tnp_Tn5 PF02281.16 ABK70547.1 - 0.038 13.7 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 Transposase Tn5 dimerisation domain Amidase PF01425.21 ABK70548.1 - 1.2e-110 370.6 0.4 1.5e-110 370.3 0.4 1.0 1 0 0 1 1 1 1 Amidase IclR PF01614.18 ABK70549.1 - 1.3e-20 73.5 0.0 2.1e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 ABK70549.1 - 3.8e-11 42.6 0.0 7.9e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 ABK70549.1 - 0.0011 18.7 0.0 0.0029 17.4 0.0 1.7 1 0 0 1 1 1 1 MarR family Phage_rep_O PF04492.13 ABK70549.1 - 0.024 15.2 0.0 0.049 14.2 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage replication protein O SRP54 PF00448.22 ABK70550.1 - 5.1e-67 225.3 0.0 9.2e-67 224.5 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 ABK70550.1 - 2.3e-30 105.1 0.2 5.2e-30 104.0 0.2 1.6 1 0 0 1 1 1 1 Signal peptide binding domain SRP54_N PF02881.19 ABK70550.1 - 4.5e-21 74.8 0.2 1.1e-20 73.6 0.2 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.23 ABK70550.1 - 1.1e-05 25.5 0.0 3.2e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain APS_kinase PF01583.20 ABK70550.1 - 0.00058 19.8 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase Zeta_toxin PF06414.12 ABK70550.1 - 0.0014 18.0 1.6 0.0027 17.0 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.6 ABK70550.1 - 0.0099 16.0 0.1 0.02 15.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ABK70550.1 - 0.011 16.3 0.0 0.025 15.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 ABK70550.1 - 0.011 14.7 0.4 0.024 13.6 0.4 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 ABK70550.1 - 0.015 15.6 0.0 0.031 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ABK70550.1 - 0.016 15.6 0.5 0.046 14.1 0.1 2.1 2 1 1 3 3 3 0 AAA ATPase domain Thymidylate_kin PF02223.17 ABK70550.1 - 0.022 14.4 0.1 0.039 13.6 0.1 1.4 1 0 0 1 1 1 0 Thymidylate kinase ArsA_ATPase PF02374.15 ABK70550.1 - 0.024 13.8 2.8 0.075 12.2 0.1 2.8 4 0 0 4 4 4 0 Anion-transporting ATPase cobW PF02492.19 ABK70550.1 - 0.028 14.0 1.5 0.43 10.2 1.5 2.3 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 ABK70550.1 - 0.033 13.9 1.0 0.093 12.4 1.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.6 ABK70550.1 - 0.035 14.0 0.1 0.08 12.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 ABK70550.1 - 0.036 14.0 0.1 0.067 13.1 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B TsaE PF02367.17 ABK70550.1 - 0.046 13.7 0.6 0.11 12.5 0.1 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 ABK70550.1 - 0.064 13.2 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 NTPase TctA PF01970.16 ABK70550.1 - 0.092 11.4 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family 6PF2K PF01591.18 ABK70550.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase ATP_bind_1 PF03029.17 ABK70550.1 - 0.17 11.7 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 ABK70550.1 - 0.17 11.6 0.0 0.5 10.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 ABK70550.1 - 0.21 11.5 1.3 0.33 10.9 0.6 1.7 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 ABK70550.1 - 0.45 10.1 5.6 2.7 7.5 2.3 3.1 2 1 0 2 2 2 0 AAA domain Pyr_redox_2 PF07992.14 ABK70551.1 - 4.4e-62 210.0 1.2 6.6e-62 209.4 1.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ABK70551.1 - 1.1e-22 80.3 9.6 4.3e-18 65.7 0.7 3.8 4 0 0 4 4 3 3 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 ABK70551.1 - 1.8e-13 50.8 0.0 5.2e-13 49.4 0.0 1.8 1 0 0 1 1 1 1 Reductase C-terminal Lycopene_cycl PF05834.12 ABK70551.1 - 8.2e-07 28.4 3.7 0.004 16.3 0.4 3.3 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_9 PF13454.6 ABK70551.1 - 1.2e-06 28.6 5.8 1.9 8.5 0.5 4.4 3 1 1 4 4 4 3 FAD-NAD(P)-binding DAO PF01266.24 ABK70551.1 - 2.9e-06 27.1 9.8 0.0025 17.5 0.2 4.3 3 1 1 4 4 4 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ABK70551.1 - 8.9e-06 25.2 0.0 4.5e-05 22.9 0.0 1.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ABK70551.1 - 1.5e-05 24.3 0.0 0.2 10.8 0.0 2.9 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 ABK70551.1 - 2.2e-05 23.7 5.1 0.0015 17.7 0.1 3.8 3 1 1 4 4 4 1 Glucose inhibited division protein A TrkA_N PF02254.18 ABK70551.1 - 3.1e-05 24.2 0.0 0.024 14.9 0.0 2.7 2 1 0 2 2 2 1 TrkA-N domain NAD_binding_7 PF13241.6 ABK70551.1 - 0.00012 22.5 0.1 0.75 10.3 0.0 2.6 2 1 0 2 2 2 2 Putative NAD(P)-binding Trp_halogenase PF04820.14 ABK70551.1 - 0.00017 20.6 2.6 0.41 9.4 0.8 3.2 2 1 1 3 3 3 1 Tryptophan halogenase NAD_binding_8 PF13450.6 ABK70551.1 - 0.00019 21.6 8.2 0.0047 17.1 0.2 3.5 4 0 0 4 4 3 2 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 ABK70551.1 - 0.00048 19.5 0.4 0.005 16.2 0.3 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase 2-Hacid_dh_C PF02826.19 ABK70551.1 - 0.003 16.9 0.6 0.0079 15.6 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 ABK70551.1 - 0.0045 16.9 0.2 0.011 15.6 0.2 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 ABK70551.1 - 0.0056 15.4 1.2 4.1 6.0 0.1 3.5 3 1 1 4 4 4 1 HI0933-like protein Shikimate_DH PF01488.20 ABK70551.1 - 0.01 15.9 0.3 0.44 10.6 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 ABK70551.1 - 0.011 15.4 0.1 0.028 14.1 0.1 1.8 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 ABK70551.1 - 0.011 15.1 0.1 0.019 14.3 0.1 1.3 1 0 0 1 1 1 0 ThiF family AlaDh_PNT_C PF01262.21 ABK70551.1 - 0.011 15.0 4.4 0.07 12.4 0.8 2.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 ABK70551.1 - 0.034 14.4 0.0 5.9 7.2 0.1 2.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 ABK70551.1 - 0.039 13.5 0.1 0.068 12.7 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_2 PF00890.24 ABK70551.1 - 0.039 13.0 5.2 0.77 8.8 2.1 3.1 2 1 0 2 2 2 0 FAD binding domain DUF1188 PF06690.11 ABK70551.1 - 0.049 13.2 0.0 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) UPF0146 PF03686.13 ABK70551.1 - 0.1 12.5 0.3 1 9.2 0.0 2.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0146) HCBP_related PF06594.11 ABK70551.1 - 0.16 11.9 0.0 3.3 7.7 0.0 2.8 2 0 0 2 2 2 0 Haemolysin-type calcium binding protein related domain FAD_binding_3 PF01494.19 ABK70551.1 - 0.49 9.6 4.7 0.11 11.7 0.8 1.9 2 0 0 2 2 2 0 FAD binding domain Gln-synt_C PF00120.24 ABK70552.1 - 4.6e-99 331.7 0.0 5.5e-99 331.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 ABK70552.1 - 4.4e-05 23.3 0.0 9.1e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase N-terminal domain Gln-synt_N PF03951.19 ABK70552.1 - 0.00041 20.0 0.0 0.00097 18.8 0.0 1.6 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain 4HBT_3 PF13622.6 ABK70553.1 - 5.3e-29 102.2 5.3 6.9e-29 101.8 5.3 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 ABK70553.1 - 3.4e-06 26.9 0.1 1.4e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA thioesterase 4HBT PF03061.22 ABK70553.1 - 0.015 15.6 0.1 1.7 9.0 0.0 2.4 2 0 0 2 2 2 0 Thioesterase superfamily Complex1_30kDa PF00329.19 ABK70554.1 - 1.3e-39 135.6 0.0 1.7e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit ZnuA PF01297.17 ABK70556.1 - 1.8e-39 135.7 0.4 2.1e-39 135.5 0.4 1.0 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic PucR PF07905.11 ABK70556.1 - 0.0012 19.2 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 Purine catabolism regulatory protein-like family RGCC PF15151.6 ABK70556.1 - 0.063 13.5 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Response gene to complement 32 protein family FCD PF07729.12 ABK70557.1 - 5.9e-25 88.1 9.1 1e-24 87.3 9.1 1.4 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 ABK70557.1 - 1.4e-14 53.4 0.1 2.6e-14 52.6 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family DprA_WH PF17782.1 ABK70557.1 - 0.00024 21.2 0.5 0.043 13.9 0.1 2.7 2 0 0 2 2 2 1 DprA winged helix domain HTH_IclR PF09339.10 ABK70557.1 - 0.0003 20.5 0.3 0.44 10.4 0.0 2.8 2 0 0 2 2 2 2 IclR helix-turn-helix domain HTH_24 PF13412.6 ABK70557.1 - 0.011 15.3 0.1 0.29 10.7 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Fe_dep_repress PF01325.19 ABK70557.1 - 0.025 14.8 0.0 0.063 13.5 0.0 1.7 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain PaaX PF07848.12 ABK70557.1 - 0.072 13.3 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 PaaX-like protein Cerato-platanin PF07249.12 ABK70557.1 - 0.1 12.7 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 Cerato-platanin AbiEi_4 PF13338.6 ABK70557.1 - 2.3 8.5 11.9 14 5.9 0.2 4.4 5 1 0 5 5 5 0 Transcriptional regulator, AbiEi antitoxin Guanylate_cyc PF00211.20 ABK70558.1 - 3.9e-27 95.0 0.0 6.4e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain AAA_16 PF13191.6 ABK70558.1 - 1.5e-23 84.0 1.9 3.1e-23 83.0 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 ABK70558.1 - 0.00014 22.2 0.0 0.0014 18.9 0.0 2.5 1 1 0 1 1 1 1 AAA domain DZR PF12773.7 ABK70558.1 - 0.00022 21.1 0.2 0.00044 20.2 0.2 1.4 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 ABK70558.1 - 0.00035 20.2 2.3 0.00068 19.3 2.3 1.4 1 0 0 1 1 1 1 zinc-ribbon domain ATPase_2 PF01637.18 ABK70558.1 - 0.0011 19.0 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea zf-ribbon_3 PF13248.6 ABK70558.1 - 0.0037 16.6 0.9 0.0066 15.8 0.9 1.4 1 0 0 1 1 1 1 zinc-ribbon domain AAA_19 PF13245.6 ABK70558.1 - 0.12 12.7 0.0 0.37 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain TPR_14 PF13428.6 ABK70558.1 - 1 10.4 0.0 1 10.4 0.0 6.6 4 2 2 6 6 6 0 Tetratricopeptide repeat Peptidase_C26 PF07722.13 ABK70559.1 - 2.4e-69 233.4 0.0 2.8e-69 233.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase C26 GATase PF00117.28 ABK70559.1 - 2.9e-15 56.5 0.0 1.1e-14 54.7 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Sugar_tr PF00083.24 ABK70560.1 - 2.4e-36 125.6 27.6 2.3e-24 86.1 5.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ABK70560.1 - 3.6e-33 114.9 46.2 4.8e-26 91.5 21.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 ABK70560.1 - 0.00095 18.0 6.1 0.00095 18.0 6.1 2.0 2 0 0 2 2 2 1 LacY proton/sugar symporter SprB PF13573.6 ABK70560.1 - 0.23 11.3 7.1 0.073 12.9 1.8 2.3 2 0 0 2 2 2 0 SprB repeat Trypsin_2 PF13365.6 ABK70561.1 - 1.8e-23 84.1 5.5 2.8e-23 83.5 5.5 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 ABK70561.1 - 7.5e-12 45.4 0.1 1.6e-11 44.3 0.1 1.5 1 0 0 1 1 1 1 PDZ domain Trypsin PF00089.26 ABK70561.1 - 3.6e-08 33.5 0.5 8.4e-08 32.3 0.5 1.6 1 1 0 1 1 1 1 Trypsin PDZ PF00595.24 ABK70561.1 - 6.3e-08 32.9 0.0 1.4e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 ABK70561.1 - 8.8e-07 28.7 0.1 2.4e-06 27.3 0.1 1.8 1 0 0 1 1 1 1 PDZ domain Peptidase_S32 PF05579.13 ABK70561.1 - 0.00092 18.5 7.9 0.013 14.7 1.0 2.4 1 1 0 2 2 2 2 Equine arteritis virus serine endopeptidase S32 Peptidase_S46 PF10459.9 ABK70561.1 - 0.0049 15.6 0.4 0.94 8.0 0.0 2.0 2 0 0 2 2 2 2 Peptidase S46 Peptidase_C3 PF00548.20 ABK70561.1 - 0.056 13.4 0.0 0.088 12.7 0.0 1.2 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) MTES_1575 PF18741.1 ABK70562.1 - 0.0007 19.7 0.5 0.0014 18.7 0.5 1.6 1 0 0 1 1 1 1 REase_MTES_1575 AbiEi_1 PF09407.10 ABK70562.1 - 0.024 15.0 0.2 0.049 13.9 0.0 1.7 2 0 0 2 2 2 0 AbiEi antitoxin C-terminal domain Acyl_transf_3 PF01757.22 ABK70563.1 - 2.2e-12 46.7 29.4 3.9e-12 45.9 29.2 1.5 1 1 0 1 1 1 1 Acyltransferase family adh_short PF00106.25 ABK70564.1 - 4.8e-25 88.2 0.0 8e-25 87.4 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK70564.1 - 2.7e-18 66.4 1.1 6.3e-18 65.2 1.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK70564.1 - 3.9e-09 36.7 1.4 9.8e-08 32.1 1.5 2.0 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 ABK70564.1 - 5.9e-05 23.0 0.6 8.4e-05 22.5 0.6 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ABK70564.1 - 0.0019 17.7 0.1 0.0043 16.5 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ABK70564.1 - 0.036 13.2 0.1 0.13 11.4 0.1 1.9 1 1 0 1 1 1 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 ABK70564.1 - 0.073 12.5 0.0 0.19 11.1 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Acyl-CoA_dh_1 PF00441.24 ABK70566.1 - 8e-27 94.3 0.8 1.3e-26 93.7 0.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK70566.1 - 6.1e-13 49.4 0.2 1.3e-12 48.4 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ABK70566.1 - 3.6e-11 43.5 1.1 3.6e-11 43.5 1.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK70566.1 - 0.0023 18.1 0.0 0.0043 17.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acetyltransf_1 PF00583.25 ABK70568.1 - 7.3e-14 52.0 0.0 9.3e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ABK70568.1 - 7.5e-12 45.5 0.0 1.1e-11 45.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ABK70568.1 - 1.9e-11 44.0 0.0 2.5e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ABK70568.1 - 1.3e-09 38.2 0.0 0.00043 20.3 0.0 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 ABK70568.1 - 0.0001 22.4 0.3 0.00015 22.0 0.3 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 ABK70568.1 - 0.00059 19.6 0.0 0.00069 19.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 ABK70568.1 - 0.0037 17.4 0.0 0.0066 16.6 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 ABK70568.1 - 0.053 13.5 0.0 0.082 12.9 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein ABC_tran PF00005.27 ABK70569.1 - 2.4e-29 102.6 0.0 3.6e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK70569.1 - 3.1e-11 43.6 0.2 0.00014 21.8 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK70569.1 - 6.4e-09 35.6 0.5 3.3e-08 33.2 0.5 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ABK70569.1 - 8.9e-05 22.9 0.2 0.00014 22.3 0.2 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 ABK70569.1 - 0.0002 21.0 1.4 0.00031 20.4 0.5 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 ABK70569.1 - 0.0015 18.7 0.2 0.032 14.5 0.2 2.5 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 ABK70569.1 - 0.0052 17.3 0.4 0.01 16.4 0.4 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ABK70569.1 - 0.0078 16.5 0.3 0.56 10.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 ABK70569.1 - 0.009 15.8 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 ABK70569.1 - 0.019 14.9 0.2 0.097 12.6 0.1 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_25 PF13481.6 ABK70569.1 - 0.022 14.3 4.4 0.46 10.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ABK70569.1 - 0.055 13.6 1.0 0.46 10.6 1.0 2.1 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 ABK70569.1 - 0.18 11.2 1.3 0.19 11.1 0.1 1.6 2 0 0 2 2 2 0 Bacterial TniB protein FtsK_SpoIIIE PF01580.18 ABK70569.1 - 0.22 10.8 3.1 0.58 9.5 0.5 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_ATPase PF09818.9 ABK70569.1 - 0.28 9.9 4.2 8 5.1 1.1 2.5 2 1 0 2 2 2 0 Predicted ATPase of the ABC class KH_4 PF13083.6 ABK70570.1 - 1.5e-20 72.8 0.2 1.7e-20 72.7 0.2 1.1 1 0 0 1 1 1 1 KH domain KH_1 PF00013.29 ABK70570.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 KH domain KH_2 PF07650.17 ABK70570.1 - 0.072 12.9 0.4 0.11 12.3 0.3 1.4 1 1 0 1 1 1 0 KH domain DUF2505 PF10698.9 ABK70571.1 - 1.3e-53 181.3 0.1 1.4e-53 181.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2505) His_Phos_1 PF00300.22 ABK70572.1 - 4.9e-33 114.5 0.0 5.5e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) YceD PF02620.17 ABK70573.1 - 3.3e-26 91.8 0.0 4.4e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 Large ribosomal RNA subunit accumulation protein YceD Acetyltransf_1 PF00583.25 ABK70574.1 - 3.6e-07 30.4 0.0 5.3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 ABK70574.1 - 0.0001 22.4 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ABK70574.1 - 0.0012 18.7 0.0 0.0017 18.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ABK70574.1 - 0.0026 18.1 0.1 0.0042 17.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain IN_DBD_C PF00552.21 ABK70574.1 - 0.03 13.6 0.0 0.078 12.3 0.0 1.7 2 0 0 2 2 2 0 Integrase DNA binding domain FR47 PF08445.10 ABK70574.1 - 0.041 13.8 0.1 0.076 13.0 0.1 1.4 1 0 0 1 1 1 0 FR47-like protein HTH_IclR PF09339.10 ABK70575.1 - 2.4e-11 43.3 0.0 4.8e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 ABK70575.1 - 8.4e-07 28.8 0.4 4.2e-06 26.5 0.1 2.3 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 ABK70575.1 - 8e-06 26.3 0.0 0.00015 22.2 0.0 2.4 2 0 0 2 2 2 1 Winged helix DNA-binding domain IclR PF01614.18 ABK70575.1 - 0.00051 19.9 0.0 0.021 14.6 0.1 2.4 2 0 0 2 2 2 1 Bacterial transcriptional regulator HTH_24 PF13412.6 ABK70575.1 - 0.00072 19.1 0.0 0.002 17.7 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 ABK70575.1 - 0.0017 18.1 0.1 0.099 12.5 0.0 2.7 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain Rrf2 PF02082.20 ABK70575.1 - 0.0019 18.5 0.0 0.0058 17.0 0.0 1.8 2 0 0 2 2 2 1 Transcriptional regulator PuR_N PF09182.10 ABK70575.1 - 0.0076 16.2 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 Bacterial purine repressor, N-terminal MarR PF01047.22 ABK70575.1 - 0.016 15.1 0.0 0.043 13.7 0.0 1.8 2 0 0 2 2 2 0 MarR family Rnk_N PF14760.6 ABK70575.1 - 0.021 15.3 0.3 1.4 9.4 0.2 2.7 2 0 0 2 2 2 0 Rnk N-terminus TrmB PF01978.19 ABK70575.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Isochorismatase PF00857.20 ABK70576.1 - 6.4e-37 127.4 0.0 7.8e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family HemY_N PF07219.13 ABK70577.1 - 0.41 10.9 2.8 4.6 7.5 2.8 2.3 1 1 0 1 1 1 0 HemY protein N-terminus DDE_3 PF13358.6 ABK70578.1 - 6.3e-24 84.4 0.0 9.8e-24 83.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.6 ABK70578.1 - 3.9e-15 55.6 0.2 1.5e-14 53.8 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 ABK70578.1 - 1.2e-12 47.8 4.7 3.6e-11 43.0 0.2 2.8 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_23 PF13384.6 ABK70578.1 - 2.4e-11 43.1 1.9 1.2e-10 40.9 0.0 2.6 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 ABK70578.1 - 8.4e-10 39.1 0.1 3.6e-09 37.1 0.0 2.1 1 1 1 2 2 2 1 Homeodomain-like domain HTH_50 PF18024.1 ABK70578.1 - 6e-07 29.0 0.1 1.7e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 ABK70578.1 - 2.7e-06 27.8 0.1 6.2e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 leucine-zipper of insertion element IS481 HTH_Tnp_1 PF01527.20 ABK70578.1 - 0.028 14.7 0.1 0.096 13.0 0.0 1.9 2 0 0 2 2 2 0 Transposase HTH_1 PF00126.27 ABK70578.1 - 0.058 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_6 PF01418.17 ABK70578.1 - 0.079 12.9 0.0 2.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family rve_2 PF13333.6 ABK70578.1 - 0.1 12.8 0.0 1.3 9.2 0.0 2.2 2 0 0 2 2 2 0 Integrase core domain Erf4 PF10256.9 ABK70578.1 - 0.18 11.9 0.0 2.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family Lactate_perm PF02652.14 ABK70579.1 - 7.4e-140 467.1 35.5 9.6e-140 466.8 35.5 1.1 1 0 0 1 1 1 1 L-lactate permease PE-PPE PF08237.11 ABK70580.1 - 6.6e-19 68.4 0.1 1.4e-18 67.3 0.1 1.5 1 1 0 1 1 1 1 PE-PPE domain PI3K_1B_p101 PF10486.9 ABK70580.1 - 0.33 8.7 2.0 0.43 8.3 2.0 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit MFS_1 PF07690.16 ABK70581.1 - 6.6e-47 160.1 46.8 6.6e-47 160.1 46.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK70581.1 - 7e-07 28.5 26.9 7.7e-07 28.3 6.2 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 ABK70581.1 - 0.0048 15.8 5.9 0.0048 15.8 5.9 2.2 2 0 0 2 2 2 1 MFS_1 like family OATP PF03137.20 ABK70581.1 - 0.045 12.0 18.9 0.3 9.3 8.3 3.0 2 2 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family GATase_3 PF07685.14 ABK70582.1 - 1.5e-22 80.2 0.0 2e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.23 ABK70582.1 - 7.9e-20 71.2 0.0 1.2e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 ABK70582.1 - 2.2e-16 60.3 0.3 3.6e-11 43.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain DJ-1_PfpI PF01965.24 ABK70582.1 - 0.0012 18.6 0.1 0.0026 17.6 0.0 1.6 2 0 0 2 2 2 1 DJ-1/PfpI family MobB PF03205.14 ABK70582.1 - 0.041 13.8 0.1 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B VirC1 PF07015.11 ABK70582.1 - 0.074 12.3 0.1 7.4 5.8 0.1 2.3 2 0 0 2 2 2 0 VirC1 protein SNO PF01174.19 ABK70582.1 - 0.1 12.4 0.0 0.28 11.0 0.0 1.6 2 0 0 2 2 2 0 SNO glutamine amidotransferase family DUF417 PF04224.12 ABK70583.1 - 0.24 11.0 2.6 2.6 7.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF417 MerC PF03203.14 ABK70583.1 - 1.7 9.1 14.1 1.6 9.2 1.9 2.5 1 1 1 2 2 2 0 MerC mercury resistance protein Lactamase_B_2 PF12706.7 ABK70584.1 - 7.2e-51 172.6 0.4 9.6e-51 172.2 0.4 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ABK70584.1 - 5.4e-17 62.2 0.0 6.8e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ABK70584.1 - 1.2 9.2 7.2 12 5.9 5.9 2.8 2 1 0 2 2 2 0 Metallo-beta-lactamase superfamily DDE_Tnp_ISL3 PF01610.17 ABK70585.1 - 1.6e-64 217.9 0.0 2.1e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Transposase zf-ISL3 PF14690.6 ABK70585.1 - 1.1e-09 38.8 4.6 1.8e-09 38.1 2.5 2.5 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HTH_Tnp_ISL3 PF13542.6 ABK70585.1 - 2.4e-08 33.2 1.6 7e-08 31.8 1.6 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 Response_reg PF00072.24 ABK70586.1 - 2.4e-20 72.7 0.0 2.9e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain FAD_binding_4 PF01565.23 ABK70587.1 - 1.6e-26 92.7 4.3 2.5e-26 92.0 4.3 1.4 1 0 0 1 1 1 1 FAD binding domain NYN_YacP PF05991.11 ABK70588.1 - 6.4e-14 52.2 0.0 7.9e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 YacP-like NYN domain DUF188 PF02639.14 ABK70588.1 - 1.4e-05 24.8 0.1 1.7e-05 24.5 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized BCR, YaiI/YqxD family COG1671 PIN_9 PF18477.1 ABK70588.1 - 0.0026 18.0 0.0 0.0032 17.8 0.0 1.2 1 0 0 1 1 1 1 PIN like domain HTH_5 PF01022.20 ABK70589.1 - 2.7e-15 56.0 0.3 2.7e-15 56.0 0.3 2.0 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 ABK70589.1 - 4.6e-10 39.4 1.0 7.8e-10 38.7 1.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Rrf2 PF02082.20 ABK70589.1 - 0.00042 20.6 0.1 0.00055 20.2 0.1 1.2 1 0 0 1 1 1 1 Transcriptional regulator TrmB PF01978.19 ABK70589.1 - 0.00095 19.0 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB PaaX PF07848.12 ABK70589.1 - 0.003 17.8 0.0 0.005 17.0 0.0 1.4 1 0 0 1 1 1 1 PaaX-like protein MarR_2 PF12802.7 ABK70589.1 - 0.0042 16.9 0.5 0.013 15.4 0.5 1.9 1 1 0 1 1 1 1 MarR family HxlR PF01638.17 ABK70589.1 - 0.013 15.3 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 HxlR-like helix-turn-helix HTH_24 PF13412.6 ABK70589.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HpcH_HpaI PF03328.14 ABK70590.1 - 1.4e-45 155.1 0.2 2.1e-45 154.6 0.2 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 ABK70590.1 - 9.6e-11 41.4 0.0 1.5e-05 24.3 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PEP-utilizers_C PF02896.18 ABK70590.1 - 0.056 12.5 0.0 0.075 12.1 0.0 1.2 1 0 0 1 1 1 0 PEP-utilising enzyme, TIM barrel domain Rieske PF00355.26 ABK70591.1 - 1.7e-18 66.3 0.0 3.8e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain LON_substr_bdg PF02190.16 ABK70592.1 - 7.4e-17 61.9 0.0 1e-16 61.5 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Abhydrolase_6 PF12697.7 ABK70593.1 - 3.4e-20 73.6 8.8 3.8e-20 73.4 8.8 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK70593.1 - 7.6e-07 28.6 0.8 2.7e-06 26.8 0.8 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 ABK70593.1 - 0.013 15.4 0.2 0.036 13.9 0.1 1.8 2 0 0 2 2 2 0 Serine hydrolase DUF3786 PF12654.7 ABK70593.1 - 0.06 12.9 0.0 0.089 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) Dabb PF07876.12 ABK70594.1 - 2.1e-14 53.9 0.0 2.3e-14 53.8 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain BPD_transp_1 PF00528.22 ABK70595.1 - 3.4e-09 36.7 40.2 6.4e-07 29.3 40.1 2.8 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component DUF4051 PF13260.6 ABK70595.1 - 0.38 10.5 6.1 0.087 12.6 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) adh_short PF00106.25 ABK70596.1 - 4e-55 186.3 4.1 5e-55 186.0 4.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK70596.1 - 8.9e-53 179.2 9.1 1.1e-52 178.9 9.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK70596.1 - 8.2e-10 38.9 3.7 1.2e-09 38.4 3.7 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK70596.1 - 2.8e-05 23.7 1.4 7.6e-05 22.3 1.4 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 ABK70596.1 - 0.0046 17.1 0.1 0.013 15.7 0.1 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 ABK70596.1 - 0.0064 16.4 1.5 0.0091 15.9 1.0 1.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MTES_1575 PF18741.1 ABK70598.1 - 2.4e-07 30.9 0.2 4.2e-07 30.0 0.2 1.4 1 0 0 1 1 1 1 REase_MTES_1575 DUF559 PF04480.12 ABK70598.1 - 0.0005 19.9 0.1 0.00087 19.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF559) DUF1769 PF08588.10 ABK70598.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) zf-RING_7 PF02591.15 ABK70599.1 - 1.6e-11 44.2 2.0 4.5e-11 42.7 2.0 1.8 1 0 0 1 1 1 1 C4-type zinc ribbon domain ATG16 PF08614.11 ABK70599.1 - 0.002 18.4 29.1 0.0066 16.7 18.3 2.2 1 1 0 2 2 2 1 Autophagy protein 16 (ATG16) Rab5-bind PF09311.11 ABK70599.1 - 0.002 17.6 16.1 0.0021 17.5 14.8 1.6 1 1 1 2 2 2 1 Rabaptin-like protein CALCOCO1 PF07888.11 ABK70599.1 - 0.0027 16.7 22.0 0.0035 16.3 22.0 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Prok-RING_1 PF14446.6 ABK70599.1 - 0.0068 16.3 2.8 0.014 15.3 2.8 1.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 APG6_N PF17675.1 ABK70599.1 - 0.0081 16.7 29.0 0.11 13.1 15.3 2.5 2 0 0 2 2 2 2 Apg6 coiled-coil region Zn-ribbon_8 PF09723.10 ABK70599.1 - 0.014 15.5 0.4 0.051 13.7 0.2 2.0 2 0 0 2 2 1 0 Zinc ribbon domain TMF_TATA_bd PF12325.8 ABK70599.1 - 0.041 14.1 19.4 0.38 11.0 9.8 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF2353 PF09789.9 ABK70599.1 - 0.046 13.1 16.7 0.056 12.8 16.7 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) AAA_13 PF13166.6 ABK70599.1 - 0.12 11.0 3.5 0.14 10.8 3.5 1.3 1 0 0 1 1 1 0 AAA domain Seryl_tRNA_N PF02403.22 ABK70599.1 - 0.13 12.5 17.7 0.46 10.7 8.4 3.2 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF2408 PF10303.9 ABK70599.1 - 0.13 12.8 6.8 0.098 13.2 2.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) zf-ribbon_3 PF13248.6 ABK70599.1 - 0.18 11.3 0.1 0.18 11.3 0.1 1.7 2 0 0 2 2 1 0 zinc-ribbon domain zf-ACC PF17848.1 ABK70599.1 - 0.2 11.8 0.0 0.53 10.4 0.0 1.7 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain RmuC PF02646.16 ABK70599.1 - 0.22 10.6 9.2 0.54 9.3 0.2 2.4 1 1 0 2 2 2 0 RmuC family CENP-H PF05837.12 ABK70599.1 - 0.23 11.9 18.0 0.12 12.7 8.3 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF3584 PF12128.8 ABK70599.1 - 0.33 8.4 22.6 0.74 7.2 22.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) CENP-K PF11802.8 ABK70599.1 - 0.42 10.1 10.1 0.7 9.4 10.1 1.3 1 1 0 1 1 1 0 Centromere-associated protein K DUF4763 PF15960.5 ABK70599.1 - 0.47 9.7 18.3 0.37 10.1 14.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) DNA_RNApol_7kD PF03604.13 ABK70599.1 - 0.51 10.1 4.4 3.6 7.4 4.4 2.2 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit SKA2 PF16740.5 ABK70599.1 - 0.57 10.0 14.2 0.63 9.8 9.1 2.8 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 2 STAT_alpha PF01017.20 ABK70599.1 - 0.66 9.8 11.8 0.64 9.9 8.7 2.0 1 1 1 2 2 2 0 STAT protein, all-alpha domain Vps54_N PF10475.9 ABK70599.1 - 0.68 9.2 5.3 0.9 8.8 4.8 1.5 1 1 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex MscS_porin PF12795.7 ABK70599.1 - 0.71 9.4 26.1 0.76 9.3 23.1 2.1 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DUF5320 PF17253.2 ABK70599.1 - 0.78 10.8 10.2 8 7.6 0.7 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5320) Fez1 PF06818.15 ABK70599.1 - 0.8 10.1 16.5 1.1 9.6 16.2 1.4 1 1 0 1 1 1 0 Fez1 GAS PF13851.6 ABK70599.1 - 0.88 8.9 19.5 0.55 9.6 2.7 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding GCN5L1 PF06320.13 ABK70599.1 - 1.2 9.4 9.8 1.1 9.5 3.5 2.7 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) IFT57 PF10498.9 ABK70599.1 - 1.2 8.0 12.7 6.6 5.6 7.9 2.0 1 1 0 2 2 2 0 Intra-flagellar transport protein 57 Nsp1_C PF05064.13 ABK70599.1 - 1.5 8.6 11.4 16 5.3 9.8 2.9 1 1 2 3 3 3 0 Nsp1-like C-terminal region Tho2 PF11262.8 ABK70599.1 - 1.6 7.8 5.6 4.9 6.3 5.6 1.7 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Herpes_UL6 PF01763.16 ABK70599.1 - 2.1 6.8 5.6 2.2 6.7 4.8 1.4 1 1 0 1 1 1 0 Herpesvirus UL6 like DUF1664 PF07889.12 ABK70599.1 - 2.1 8.4 9.7 5.4 7.1 0.2 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.19 ABK70599.1 - 3.2 5.5 6.4 3.9 5.3 6.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mod_r PF07200.13 ABK70599.1 - 3.5 7.7 16.1 10 6.2 10.5 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Nop53 PF07767.11 ABK70599.1 - 4.3 6.6 15.8 5.8 6.2 15.8 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) FlaC_arch PF05377.11 ABK70599.1 - 4.7 7.7 7.9 68 4.0 1.4 3.6 3 2 0 3 3 3 0 Flagella accessory protein C (FlaC) YkyA PF10368.9 ABK70599.1 - 4.7 6.8 12.5 17 5.0 9.6 2.0 1 1 0 2 2 2 0 Putative cell-wall binding lipoprotein DUF724 PF05266.14 ABK70599.1 - 4.8 7.0 13.5 2.7 7.8 8.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF3683 PF12447.8 ABK70599.1 - 4.8 7.3 9.7 2.2 8.4 3.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3683) YabA PF06156.13 ABK70599.1 - 5.6 7.7 14.0 19 6.0 10.4 2.5 1 1 0 2 2 2 0 Initiation control protein YabA Baculo_PEP_C PF04513.12 ABK70599.1 - 5.8 6.9 9.1 9.3 6.3 4.3 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMPIT PF07851.13 ABK70599.1 - 6.1 6.0 9.4 2.1 7.5 6.1 1.7 2 0 0 2 2 2 0 TMPIT-like protein EMP24_GP25L PF01105.24 ABK70599.1 - 7.1 6.5 8.7 1.7 8.5 0.2 2.4 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Spc7 PF08317.11 ABK70599.1 - 8.2 5.2 21.9 6.7 5.5 1.0 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3450 PF11932.8 ABK70599.1 - 9.6 5.4 20.2 0.73 9.1 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) MerR_1 PF13411.6 ABK70600.1 - 7e-20 70.9 0.1 1.8e-19 69.5 0.0 1.8 3 0 0 3 3 3 1 MerR HTH family regulatory protein MerR PF00376.23 ABK70600.1 - 1.1e-06 28.3 2.8 1.6e-06 27.7 0.3 2.4 3 0 0 3 3 3 1 MerR family regulatory protein HemN_C PF06969.16 ABK70600.1 - 0.0081 16.2 0.1 1.1 9.4 0.0 3.1 2 1 0 2 2 2 1 HemN C-terminal domain HTH_10 PF04967.12 ABK70600.1 - 0.034 14.0 0.2 14 5.5 0.0 3.8 2 1 2 4 4 4 0 HTH DNA binding domain AbiEi_4 PF13338.6 ABK70600.1 - 0.064 13.4 3.3 0.18 12.0 0.4 2.8 2 1 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin MerR-DNA-bind PF09278.11 ABK70600.1 - 0.085 13.4 1.1 0.27 11.8 0.1 2.4 2 0 0 2 2 2 0 MerR, DNA binding HTH_17 PF12728.7 ABK70600.1 - 0.09 13.0 0.2 0.51 10.6 0.0 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain Acetyltransf_CG PF14542.6 ABK70601.1 - 3.4e-25 88.0 0.0 4.7e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.25 ABK70601.1 - 0.00056 20.1 0.0 0.00067 19.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ABK70601.1 - 0.00084 19.7 0.0 0.00097 19.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ABK70601.1 - 0.0092 15.9 0.0 0.011 15.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ABK70601.1 - 0.058 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1841 PF08897.11 ABK70601.1 - 0.14 12.2 0.0 2 8.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1841) Abhydrolase_3 PF07859.13 ABK70602.1 - 6.9e-19 68.5 0.0 1.3e-18 67.7 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ABK70602.1 - 5.4e-15 55.3 0.1 3.5e-14 52.6 0.1 1.9 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 ABK70602.1 - 1.2e-14 54.3 0.0 4.1e-14 52.6 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 ABK70602.1 - 0.0037 16.6 0.0 0.21 10.8 0.0 2.8 3 0 0 3 3 3 1 Serine aminopeptidase, S33 LIP PF03583.14 ABK70602.1 - 0.058 12.7 0.0 2.5 7.3 0.0 2.1 1 1 1 2 2 2 0 Secretory lipase 3HBOH PF10605.9 ABK70602.1 - 0.13 10.5 0.1 0.18 10.0 0.1 1.1 1 0 0 1 1 1 0 3HB-oligomer hydrolase (3HBOH) Mycobact_memb PF05423.13 ABK70603.1 - 2.7e-51 173.2 0.2 3e-51 173.0 0.2 1.0 1 0 0 1 1 1 1 Mycobacterium membrane protein DUF4811 PF16069.5 ABK70603.1 - 0.058 13.3 0.0 0.079 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4811) AMP-binding PF00501.28 ABK70604.1 - 1.6e-103 346.5 0.0 1.9e-103 346.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK70604.1 - 7.7e-21 74.9 0.6 1.7e-20 73.8 0.6 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pro_isomerase PF00160.21 ABK70605.1 - 2.9e-49 167.4 0.1 3.3e-49 167.2 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD H2TH PF06831.14 ABK70606.1 - 1.1e-17 63.8 0.0 1.8e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.24 ABK70606.1 - 1.2e-15 58.1 0.0 2.8e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain zf-FPG_IleRS PF06827.14 ABK70606.1 - 1.2e-07 31.5 1.3 2e-07 30.7 1.3 1.4 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS zf-TFIIB PF13453.6 ABK70606.1 - 0.0038 16.5 2.6 0.007 15.7 2.6 1.4 1 0 0 1 1 1 1 Transcription factor zinc-finger Ribosomal_S13 PF00416.22 ABK70606.1 - 0.0062 16.9 0.0 0.0099 16.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 ABK70606.1 - 0.057 12.2 0.0 0.073 11.8 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF2752 PF10825.8 ABK70606.1 - 1.4 9.0 4.5 0.8 9.8 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2752) zf-RRN7 PF11781.8 ABK70606.1 - 1.5 8.5 3.6 5 6.9 3.6 1.8 1 1 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Methyltransf_2 PF00891.18 ABK70607.1 - 4.2e-50 170.0 0.1 5.3e-50 169.6 0.1 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 ABK70607.1 - 1.5e-09 37.7 0.4 4.8e-09 36.1 0.4 1.9 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_31 PF13847.6 ABK70607.1 - 0.0061 16.4 0.0 0.0096 15.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABK70607.1 - 0.023 15.4 0.2 0.075 13.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_PK PF05891.12 ABK70607.1 - 0.035 13.6 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase adh_short PF00106.25 ABK70608.1 - 7.9e-48 162.5 0.1 9.3e-48 162.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK70608.1 - 3.4e-39 134.8 0.2 4.2e-39 134.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK70608.1 - 5.4e-12 46.0 0.8 7.5e-12 45.5 0.8 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK70608.1 - 0.0057 16.1 0.1 0.19 11.2 0.1 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Isochorismatase PF00857.20 ABK70609.1 - 9.1e-26 91.1 0.0 1.1e-25 90.9 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family baeRF_family2 PF18844.1 ABK70609.1 - 0.074 13.1 0.6 0.28 11.3 0.1 2.0 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 2 GAF_2 PF13185.6 ABK70610.1 - 3e-27 95.6 6.3 3.9e-17 62.8 0.1 2.7 2 0 0 2 2 2 2 GAF domain GAF PF01590.26 ABK70610.1 - 4.9e-26 91.9 0.4 2.8e-13 50.6 0.0 2.7 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 ABK70610.1 - 2e-17 63.7 0.5 1.9e-07 31.5 0.2 3.2 2 1 0 2 2 2 2 GAF domain HisKA_3 PF07730.13 ABK70610.1 - 4.4e-10 39.9 1.8 4.4e-10 39.9 1.8 2.9 3 0 0 3 3 3 1 Histidine kinase HATPase_c PF02518.26 ABK70610.1 - 2.2e-09 37.8 0.1 1.2e-07 32.2 0.1 2.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 ABK70610.1 - 0.00017 21.6 0.1 0.00057 19.8 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 ABK70610.1 - 0.11 12.3 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF5078 PF16877.5 ABK70611.1 - 2.9e-64 214.9 5.5 3.5e-64 214.6 5.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5078) Fer4_11 PF13247.6 ABK70612.1 - 2.2e-36 124.0 6.7 2.2e-36 124.0 6.7 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Nitr_red_bet_C PF14711.6 ABK70612.1 - 1.8e-27 94.9 0.0 3e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 Respiratory nitrate reductase beta C-terminal Fer4_10 PF13237.6 ABK70612.1 - 3.9e-08 33.3 16.4 6.2e-06 26.2 3.3 3.3 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 ABK70612.1 - 2.2e-06 28.1 21.4 0.00076 20.0 6.2 3.5 2 1 1 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 ABK70612.1 - 2.7e-06 27.2 18.6 0.0043 17.1 0.2 4.4 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_2 PF12797.7 ABK70612.1 - 0.0006 19.7 24.1 0.01 15.9 1.5 4.5 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_9 PF13187.6 ABK70612.1 - 0.0011 19.1 21.0 0.0022 18.1 4.4 3.1 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 ABK70612.1 - 0.011 16.2 24.8 0.033 14.7 1.1 4.1 4 0 0 4 4 4 0 4Fe-4S binding domain Fer4 PF00037.27 ABK70612.1 - 0.012 15.3 18.3 0.035 13.9 2.2 4.5 4 0 0 4 4 4 0 4Fe-4S binding domain Fer4_13 PF13370.6 ABK70612.1 - 0.07 13.7 6.3 0.4 11.3 0.3 3.0 3 0 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_21 PF14697.6 ABK70612.1 - 0.083 13.0 21.6 0.057 13.6 1.3 3.0 3 1 0 3 3 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 ABK70612.1 - 0.087 13.6 9.7 0.34 11.7 0.6 2.8 3 0 0 3 3 2 0 4Fe-4S single cluster domain Fer4_8 PF13183.6 ABK70612.1 - 0.24 11.9 0.1 0.24 11.9 0.1 3.7 2 1 1 3 3 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 ABK70612.1 - 5.3 7.7 21.7 1.1 9.9 1.9 3.8 3 1 0 3 3 3 0 4Fe-4S dicluster domain Phosphodiest PF01663.22 ABK70613.1 - 7.2e-30 104.8 1.0 1e-28 101.0 1.0 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 ABK70613.1 - 8.6e-06 25.4 0.8 0.00049 19.6 0.8 2.4 1 1 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 ABK70613.1 - 0.00021 20.8 0.2 0.0047 16.3 0.1 2.1 2 0 0 2 2 2 1 Metalloenzyme superfamily PRiA4_ORF3 PF07929.11 ABK70614.1 - 2.1e-51 174.1 0.0 2.5e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein DNA_binding_1 PF01035.20 ABK70615.1 - 1.6e-29 101.8 0.0 3e-29 101.0 0.0 1.4 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_1N PF02870.15 ABK70615.1 - 3.7e-09 37.3 0.0 6.1e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain Haem_oxygenas_2 PF14518.6 ABK70616.1 - 1.3e-31 109.8 0.2 1.5e-31 109.5 0.2 1.1 1 0 0 1 1 1 1 Iron-containing redox enzyme TENA_THI-4 PF03070.16 ABK70616.1 - 8.9e-11 42.0 0.0 1.1e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Methyltransf_11 PF08241.12 ABK70617.1 - 2.2e-19 69.9 0.0 3.4e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABK70617.1 - 2.2e-18 66.8 0.0 3.5e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABK70617.1 - 8.4e-13 48.5 0.0 1.1e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABK70617.1 - 2.8e-12 46.7 0.0 3.4e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK70617.1 - 1.3e-09 38.7 0.0 2.2e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ABK70617.1 - 1.8e-07 30.8 0.0 2.4e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 ABK70617.1 - 0.054 13.6 0.0 0.07 13.2 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase MetW PF07021.12 ABK70617.1 - 0.057 13.0 0.0 0.083 12.5 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.11 ABK70617.1 - 0.06 12.3 0.0 0.08 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) NodS PF05401.11 ABK70617.1 - 0.15 11.7 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_29 PF03141.16 ABK70617.1 - 0.15 10.6 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 ABK70617.1 - 0.21 11.2 0.0 0.4 10.2 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain p450 PF00067.22 ABK70618.1 - 5.1e-31 107.9 0.0 2.4e-20 72.8 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Aminotran_3 PF00202.21 ABK70619.1 - 3.4e-34 118.2 0.0 7.6e-34 117.1 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-III HyaE PF07449.11 ABK70619.1 - 0.13 12.3 0.0 0.33 10.9 0.0 1.7 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE AP_endonuc_2 PF01261.24 ABK70620.1 - 7.4e-33 113.8 2.2 8.9e-33 113.5 2.2 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel EccE PF11203.8 ABK70621.1 - 6.6e-20 71.3 2.0 1.6e-19 70.1 2.0 1.7 1 0 0 1 1 1 1 Putative type VII ESX secretion system translocon, EccE Creatininase PF02633.14 ABK70622.1 - 6.3e-58 196.1 1.6 7.9e-58 195.8 1.6 1.0 1 0 0 1 1 1 1 Creatinine amidohydrolase LysR_substrate PF03466.20 ABK70623.1 - 2.5e-39 134.8 11.9 4.4e-39 134.0 11.9 1.4 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 ABK70623.1 - 1.1e-16 60.5 5.4 1.8e-16 59.8 3.5 2.3 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family PBP_like PF12727.7 ABK70623.1 - 2.8e-06 26.6 1.0 6.2e-06 25.5 0.2 2.0 2 1 1 3 3 3 1 PBP superfamily domain MarR_2 PF12802.7 ABK70623.1 - 0.0055 16.6 3.6 0.0062 16.4 0.7 2.7 3 0 0 3 3 3 1 MarR family HTH_28 PF13518.6 ABK70623.1 - 0.0096 16.0 0.3 0.031 14.4 0.3 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_20 PF12840.7 ABK70623.1 - 0.57 10.3 4.9 0.23 11.5 0.5 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain Polysacc_deac_1 PF01522.21 ABK70624.1 - 9.7e-09 35.2 0.0 1.5e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ABK70624.1 - 0.14 11.4 0.0 0.37 9.9 0.0 1.6 2 0 0 2 2 2 0 Glycosyl hydrolase family 57 DUF2243 PF10002.9 ABK70625.1 - 5.4e-47 159.4 12.3 6.2e-47 159.2 12.3 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2243) DUF4386 PF14329.6 ABK70625.1 - 0.0025 17.7 0.2 0.0025 17.7 0.2 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4386) DUF3188 PF11384.8 ABK70625.1 - 0.16 11.7 7.1 4.7 7.0 0.8 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3188) DUF3341 PF11821.8 ABK70625.1 - 0.2 11.3 0.2 0.33 10.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) HATPase_c PF02518.26 ABK70626.1 - 5.2e-28 97.8 0.1 9.6e-28 96.9 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ABK70626.1 - 1.6e-15 56.8 1.3 4.9e-15 55.3 1.3 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 ABK70626.1 - 1.6e-12 47.6 1.5 4e-12 46.3 1.5 1.8 1 0 0 1 1 1 1 HAMP domain HATPase_c_3 PF13589.6 ABK70626.1 - 0.00038 20.3 0.0 0.00072 19.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 ABK70626.1 - 0.0012 18.8 0.1 0.0026 17.7 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 ABK70626.1 - 0.0041 17.0 0.0 0.0073 16.2 0.0 1.4 1 0 0 1 1 1 1 GHKL domain HrcA PF01628.21 ABK70626.1 - 0.016 15.1 0.2 0.031 14.2 0.2 1.4 1 0 0 1 1 1 0 HrcA protein C terminal domain Herpes_gE PF02480.16 ABK70626.1 - 3.5 6.3 4.2 11 4.7 0.2 2.4 3 0 0 3 3 3 0 Alphaherpesvirus glycoprotein E AMP-binding PF00501.28 ABK70627.1 - 2.8e-81 273.3 0.0 3.4e-81 273.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK70627.1 - 1.4e-10 42.0 2.2 1.1e-09 39.2 0.1 3.0 3 1 1 4 4 4 1 AMP-binding enzyme C-terminal domain TctB PF07331.11 ABK70628.1 - 1.3e-21 77.3 12.1 1.6e-21 77.0 12.1 1.0 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family Phage_holin_2_1 PF04971.12 ABK70628.1 - 0.0082 16.1 1.3 0.053 13.5 0.1 2.4 1 1 1 2 2 2 1 Bacteriophage P21 holin S FUSC_2 PF13515.6 ABK70628.1 - 0.58 10.3 13.3 0.042 14.0 5.4 2.2 2 1 0 2 2 2 0 Fusaric acid resistance protein-like SGL PF08450.12 ABK70629.1 - 1.3e-10 41.3 7.2 0.011 15.4 0.2 4.9 1 1 5 6 6 6 4 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 ABK70629.1 - 4.6e-05 23.2 0.1 51 4.6 0.0 6.3 7 0 0 7 7 7 0 Two component regulator propeller Phytase-like PF13449.6 ABK70629.1 - 0.0036 17.3 0.4 4.2 7.2 0.0 3.9 2 2 1 3 3 3 1 Esterase-like activity of phytase NHL PF01436.21 ABK70629.1 - 0.024 14.7 5.3 1.6 8.9 0.0 3.8 4 0 0 4 4 4 0 NHL repeat GSDH PF07995.11 ABK70629.1 - 0.05 12.9 0.0 15 4.8 0.0 3.1 2 2 0 2 2 2 0 Glucose / Sorbosone dehydrogenase DUF2255 PF10012.9 ABK70629.1 - 0.059 13.5 0.0 2.7 8.2 0.0 3.1 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2255) TetR_C_1 PF02909.17 ABK70630.1 - 9e-18 64.5 0.0 1.4e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_33 PF13305.6 ABK70630.1 - 1.9e-06 28.6 1.1 3.3e-06 27.8 0.3 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK70630.1 - 1e-05 25.2 0.0 2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family Glyco_trans_4_4 PF13579.6 ABK70630.1 - 0.055 13.9 6.7 0.096 13.1 2.0 2.2 1 1 1 2 2 2 0 Glycosyl transferase 4-like domain Metallophos PF00149.28 ABK70631.1 - 6.7e-13 49.6 0.0 1e-12 49.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ABK70631.1 - 5.3e-07 30.0 0.0 1.2e-06 28.8 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF4083 PF13314.6 ABK70631.1 - 0.21 11.6 0.6 0.86 9.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) DUF805 PF05656.14 ABK70631.1 - 1.8 9.0 6.9 3.2 8.2 6.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF805) DAO PF01266.24 ABK70632.1 - 4.9e-47 161.2 5.2 6.3e-47 160.8 5.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 ABK70632.1 - 1.1e-17 64.1 0.3 2.4e-17 63.0 0.3 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 ABK70632.1 - 6.5e-07 28.8 9.7 4.5e-06 26.0 9.7 2.1 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 ABK70632.1 - 1.1e-05 24.7 0.7 0.049 12.7 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_3 PF01494.19 ABK70632.1 - 0.00011 21.6 3.1 0.011 15.0 0.8 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 ABK70632.1 - 0.00031 20.2 0.6 0.00031 20.2 0.6 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ABK70632.1 - 0.00069 18.9 2.1 0.0019 17.5 0.4 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 ABK70632.1 - 0.0038 17.1 0.6 0.01 15.8 0.2 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 ABK70632.1 - 0.0038 17.4 3.1 0.011 15.9 1.3 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 ABK70632.1 - 0.0043 16.2 0.3 0.0067 15.6 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 ABK70632.1 - 0.015 14.5 0.4 0.038 13.2 0.4 1.6 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 ABK70632.1 - 0.055 12.2 0.9 0.08 11.6 0.9 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 ABK70632.1 - 0.07 13.7 0.2 0.17 12.4 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Peripla_BP_4 PF13407.6 ABK70633.1 - 1.5e-61 208.2 12.4 1.8e-61 208.0 12.4 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 ABK70633.1 - 1.6e-18 67.1 0.9 2.5e-18 66.5 0.6 1.3 1 1 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 ABK70633.1 - 5.4e-09 36.6 1.2 9.1e-09 35.9 0.3 1.8 2 1 0 2 2 2 1 Periplasmic binding protein-like domain NDK PF00334.19 ABK70634.1 - 1.6e-51 173.8 0.0 1.8e-51 173.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Cupin_2 PF07883.11 ABK70635.1 - 2e-06 27.4 2.7 5.4e-06 26.0 2.7 1.7 1 1 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.18 ABK70635.1 - 0.00026 20.9 0.0 0.0003 20.7 0.0 1.0 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase PCO_ADO PF07847.12 ABK70635.1 - 0.059 12.8 0.0 0.067 12.6 0.0 1.1 1 0 0 1 1 1 0 PCO_ADO Cupin_1 PF00190.22 ABK70635.1 - 0.07 12.7 0.0 0.08 12.5 0.0 1.0 1 0 0 1 1 1 0 Cupin Abhydrolase_3 PF07859.13 ABK70636.1 - 3.7e-64 216.4 0.4 4.6e-64 216.2 0.4 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 ABK70636.1 - 0.0023 16.9 0.0 0.0031 16.5 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme AXE1 PF05448.12 ABK70636.1 - 0.027 13.2 0.0 3.6 6.2 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF2237 PF09996.9 ABK70637.1 - 2.7e-50 169.2 0.0 3.1e-50 169.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) Transgly PF00912.22 ABK70639.1 - 5.5e-56 188.8 0.0 7.9e-56 188.3 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase Transpeptidase PF00905.22 ABK70639.1 - 3.2e-25 89.0 0.1 4.7e-25 88.4 0.1 1.2 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain DUF2550 PF10739.9 ABK70640.1 - 3.4e-43 146.7 0.9 4e-43 146.4 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2550) CbiC PF02570.15 ABK70641.1 - 8.7e-68 227.8 0.2 9.8e-68 227.7 0.2 1.0 1 0 0 1 1 1 1 Precorrin-8X methylmutase PknH_C PF14032.6 ABK70642.1 - 0.039 13.8 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 PknH-like extracellular domain DUF3188 PF11384.8 ABK70642.1 - 0.19 11.5 2.5 0.76 9.5 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3188) adh_short PF00106.25 ABK70643.1 - 8e-37 126.6 0.0 9.4e-37 126.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK70643.1 - 1.6e-22 80.2 0.0 1.9e-22 80.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK70643.1 - 4.6e-11 43.0 0.1 6.9e-11 42.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK70643.1 - 8.1e-06 25.5 0.0 2e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ABK70643.1 - 0.00043 20.2 0.3 0.00066 19.6 0.3 1.3 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 ABK70643.1 - 0.02 14.0 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain YbaB_DNA_bd PF02575.16 ABK70644.1 - 2.5e-12 46.8 0.7 3.1e-12 46.5 0.7 1.1 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family DUF4226 PF10774.9 ABK70644.1 - 0.014 15.6 5.7 1.1 9.6 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) SpoU_sub_bind PF08032.12 ABK70644.1 - 0.048 13.9 0.2 0.33 11.2 0.0 2.1 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding DUF4140 PF13600.6 ABK70644.1 - 0.051 14.0 1.9 0.065 13.7 1.9 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Chalcone_3 PF16036.5 ABK70644.1 - 0.084 13.0 1.4 4.7 7.3 0.1 2.0 1 1 1 2 2 2 0 Chalcone isomerase-like ABC_tran PF00005.27 ABK70645.1 - 4.3e-30 105.0 0.0 6.4e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK70645.1 - 3.2e-11 43.6 0.0 0.00015 21.7 0.1 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK70645.1 - 1.4e-06 27.9 0.0 8e-06 25.4 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 ABK70645.1 - 0.00086 19.1 0.0 0.029 14.1 0.1 2.0 1 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 ABK70645.1 - 0.0014 18.3 0.1 0.0035 17.0 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 ABK70645.1 - 0.002 18.7 0.6 0.0031 18.0 0.6 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ABK70645.1 - 0.0068 16.3 0.3 0.014 15.3 0.2 1.7 1 1 0 1 1 1 1 RsgA GTPase ABC_ATPase PF09818.9 ABK70645.1 - 0.0086 14.9 0.1 0.97 8.2 0.0 2.1 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_30 PF13604.6 ABK70645.1 - 0.029 14.1 0.2 0.1 12.3 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ABK70645.1 - 0.049 14.0 0.0 0.076 13.4 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_13 PF13166.6 ABK70645.1 - 0.16 10.6 0.0 0.39 9.3 0.0 1.5 2 0 0 2 2 2 0 AAA domain DLIC PF05783.11 ABK70645.1 - 0.22 10.3 0.1 0.3 9.9 0.1 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) DEAD PF00270.29 ABK70646.1 - 2e-20 73.3 0.0 2.9e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 ABK70646.1 - 6.2e-18 65.3 0.0 1.4e-17 64.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 ABK70646.1 - 1.6e-10 41.3 0.0 2.8e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ABK70646.1 - 0.0016 18.4 0.0 0.0025 17.9 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3701 PF12482.8 ABK70646.1 - 0.071 13.2 2.5 8.9 6.5 0.1 2.8 2 0 0 2 2 2 0 Phage integrase protein Response_reg PF00072.24 ABK70647.1 - 3.4e-30 104.5 0.1 5.3e-30 103.9 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 ABK70647.1 - 1.2e-19 69.6 0.1 2.2e-19 68.7 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 ABK70647.1 - 2.4e-06 27.1 1.5 2.9e-06 26.8 0.1 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.6 ABK70647.1 - 1.5e-05 24.7 0.5 0.00011 21.9 0.1 2.6 2 1 1 3 3 3 1 Homeodomain-like domain Sigma70_r4 PF04545.16 ABK70647.1 - 0.00036 20.0 0.2 0.00087 18.8 0.2 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_29 PF13551.6 ABK70647.1 - 0.00048 20.1 0.1 0.008 16.2 0.0 2.7 3 0 0 3 3 3 1 Winged helix-turn helix HTH_38 PF13936.6 ABK70647.1 - 0.00088 19.0 1.0 0.0036 17.0 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_ECF PF07638.11 ABK70647.1 - 0.012 15.5 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 ECF sigma factor HTH_28 PF13518.6 ABK70647.1 - 0.024 14.7 0.1 0.61 10.3 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_7 PF02796.15 ABK70647.1 - 0.037 14.1 0.1 0.07 13.2 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase DUF742 PF05331.11 ABK70647.1 - 0.037 13.8 0.1 0.44 10.4 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF742) HTH_40 PF14493.6 ABK70647.1 - 0.11 13.0 0.1 0.21 12.1 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Apolipoprotein PF01442.18 ABK70648.1 - 0.00036 20.5 28.7 0.044 13.6 28.6 2.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Senescence PF06911.12 ABK70648.1 - 0.033 14.5 17.6 0.14 12.4 14.5 2.4 2 1 0 2 2 2 0 Senescence-associated protein ApoLp-III PF07464.11 ABK70648.1 - 0.2 11.8 12.8 0.11 12.6 5.3 2.9 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Exonuc_VII_L PF02601.15 ABK70648.1 - 0.62 9.6 11.8 0.18 11.4 8.8 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF948 PF06103.11 ABK70648.1 - 1.6 9.1 5.0 4.2 7.7 0.5 3.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF883 PF05957.13 ABK70648.1 - 2.4 8.8 28.3 2 9.1 6.5 3.7 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) ParE_toxin PF05016.15 ABK70648.1 - 6.9 7.4 7.7 1.4 9.6 0.7 2.8 1 1 2 3 3 3 0 ParE toxin of type II toxin-antitoxin system, parDE AA_permease_2 PF13520.6 ABK70650.1 - 1.2e-31 110.0 53.9 3.7e-31 108.4 54.2 1.5 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.21 ABK70650.1 - 4.8e-12 45.2 47.0 5.7e-12 45.0 47.0 1.1 1 0 0 1 1 1 1 Amino acid permease ECH_1 PF00378.20 ABK70651.1 - 6.4e-51 173.1 0.0 7.4e-51 172.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK70651.1 - 1.7e-30 106.7 0.0 3.1e-28 99.2 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase MarR_2 PF12802.7 ABK70652.1 - 3.8e-13 49.1 0.6 3.8e-13 49.1 0.6 1.9 2 0 0 2 2 2 1 MarR family MarR PF01047.22 ABK70652.1 - 4.4e-10 39.3 0.1 6.6e-10 38.8 0.1 1.3 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 ABK70652.1 - 4.5e-06 27.1 0.3 7.4e-06 26.4 0.3 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_24 PF13412.6 ABK70652.1 - 2.8e-05 23.6 0.0 5.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding RPA_C PF08784.11 ABK70652.1 - 0.00021 21.9 0.0 0.00039 21.0 0.0 1.4 1 0 0 1 1 1 1 Replication protein A C terminal HxlR PF01638.17 ABK70652.1 - 0.00097 18.9 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_34 PF13601.6 ABK70652.1 - 0.014 15.5 0.0 0.03 14.5 0.0 1.5 2 0 0 2 2 2 0 Winged helix DNA-binding domain HTH_20 PF12840.7 ABK70652.1 - 0.031 14.4 0.7 0.26 11.4 0.0 2.4 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_IclR PF09339.10 ABK70652.1 - 0.053 13.3 2.0 0.14 12.0 0.1 2.4 3 0 0 3 3 3 0 IclR helix-turn-helix domain HTH_Crp_2 PF13545.6 ABK70652.1 - 0.12 12.4 0.2 0.12 12.4 0.2 1.8 2 1 0 2 2 2 0 Crp-like helix-turn-helix domain AMP-binding PF00501.28 ABK70653.1 - 2.9e-64 217.2 0.1 3.7e-64 216.9 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK70653.1 - 1.3e-20 74.1 3.7 1.4e-20 74.1 0.9 2.5 4 0 0 4 4 4 1 AMP-binding enzyme C-terminal domain HyaE PF07449.11 ABK70653.1 - 0.14 12.1 0.0 24 4.9 0.0 3.2 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE Stomoxyn PF11585.8 ABK70653.1 - 5.5 7.1 6.9 13 5.9 6.1 2.0 1 1 0 1 1 1 0 Insect antimicrobial peptide, stomoxyn AmiS_UreI PF02293.15 ABK70654.1 - 1.4e-59 200.8 16.3 1.8e-59 200.5 16.3 1.1 1 0 0 1 1 1 1 AmiS/UreI family transporter Ferritin PF00210.24 ABK70655.1 - 0.0098 15.8 0.1 0.011 15.6 0.1 1.1 1 0 0 1 1 1 1 Ferritin-like domain Acyl-CoA_dh_2 PF08028.11 ABK70656.1 - 1.6e-29 102.8 4.9 1.6e-29 102.8 4.9 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK70656.1 - 7.4e-07 29.8 0.1 1.6e-06 28.7 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ABK70656.1 - 0.0063 16.7 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Peptidase_M24 PF00557.24 ABK70658.1 - 6.1e-45 153.5 0.3 6.9e-45 153.3 0.3 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 TPPK_C PF12555.8 ABK70659.1 - 8.5e-18 64.2 8.2 1.8e-17 63.1 8.2 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphokinase C terminal Ribosomal_S9 PF00380.19 ABK70660.1 - 7.9e-42 142.6 0.0 9.3e-42 142.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 4HBT_3 PF13622.6 ABK70661.1 - 7e-59 200.1 2.9 8.5e-59 199.8 2.9 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 ABK70661.1 - 1.4e-53 180.2 0.1 2.2e-44 150.5 0.0 3.1 2 1 0 2 2 2 2 Acyl-CoA thioesterase MFS_1 PF07690.16 ABK70662.1 - 6.3e-31 107.6 57.0 5.3e-26 91.4 25.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK70662.1 - 6e-28 97.9 26.5 1.9e-21 76.5 4.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 ABK70662.1 - 2.3e-05 23.1 12.2 2.3e-05 23.1 12.2 2.1 2 0 0 2 2 2 2 MFS/sugar transport protein adh_short_C2 PF13561.6 ABK70663.1 - 1.2e-37 129.8 4.9 1.6e-37 129.3 4.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK70663.1 - 7.7e-37 126.6 1.1 1e-36 126.2 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK70663.1 - 9.4e-05 22.4 4.4 0.0025 17.8 1.1 2.4 2 1 0 2 2 2 2 KR domain ADH_zinc_N PF00107.26 ABK70663.1 - 0.38 10.7 3.7 0.38 10.7 2.0 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase SecE PF00584.20 ABK70664.1 - 4.8e-20 71.2 2.2 7.9e-20 70.5 2.2 1.4 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Docking PF08990.11 ABK70664.1 - 0.039 13.6 0.1 0.079 12.6 0.1 1.6 1 0 0 1 1 1 0 Erythronolide synthase docking LysR_substrate PF03466.20 ABK70665.1 - 1.3e-45 155.4 3.6 2.2e-45 154.6 3.6 1.4 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 ABK70665.1 - 5.7e-21 74.2 3.3 1.2e-20 73.2 3.3 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family DUF2958 PF11171.8 ABK70666.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2958) DUF3995 PF13160.6 ABK70666.1 - 0.12 12.8 3.3 2.7 8.4 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3995) DUF4131 PF13567.6 ABK70666.1 - 1.3 8.7 6.7 0.67 9.6 1.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Thymidylate_kin PF02223.17 ABK70667.1 - 3.3e-21 75.8 0.0 4e-21 75.5 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase dNK PF01712.19 ABK70667.1 - 9.3e-07 28.9 0.0 1.2e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_28 PF13521.6 ABK70667.1 - 1.2e-06 28.9 0.8 1.5e-06 28.5 0.8 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ABK70667.1 - 2e-06 28.4 0.0 4e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ABK70667.1 - 0.024 14.4 3.2 0.027 14.2 0.6 2.1 1 1 1 2 2 2 0 AAA domain SRP54 PF00448.22 ABK70667.1 - 0.028 14.0 0.1 3 7.4 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 ABK70667.1 - 0.087 13.0 1.2 0.84 9.8 1.2 2.2 1 1 0 1 1 1 0 AAA domain ArgJ PF01960.18 ABK70668.1 - 2.7e-125 418.0 11.5 3e-125 417.8 11.5 1.0 1 0 0 1 1 1 1 ArgJ family Na_Ca_ex PF01699.24 ABK70669.1 - 6.6e-54 182.0 33.3 1.2e-28 99.9 11.9 2.0 2 0 0 2 2 2 2 Sodium/calcium exchanger protein YadA_head PF05658.14 ABK70669.1 - 6.5 7.3 7.8 50 4.5 2.4 3.3 3 0 0 3 3 3 0 Head domain of trimeric autotransporter adhesin adh_short_C2 PF13561.6 ABK70670.1 - 1.7e-24 86.7 0.1 3e-15 56.4 0.0 3.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK70670.1 - 8.5e-16 58.0 0.4 2.3e-06 27.2 0.1 3.1 1 1 1 2 2 2 2 short chain dehydrogenase Epimerase PF01370.21 ABK70670.1 - 8.7e-08 31.9 0.1 1.3e-07 31.3 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ABK70670.1 - 0.065 12.6 0.0 0.26 10.6 0.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase CoA_binding_2 PF13380.6 ABK70670.1 - 0.068 13.7 0.1 0.16 12.5 0.1 1.8 1 1 0 1 1 1 0 CoA binding domain DnaB_bind PF10410.9 ABK70670.1 - 0.09 13.0 0.5 0.2 11.8 0.0 1.8 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase KR PF08659.10 ABK70670.1 - 0.1 12.5 1.5 0.38 10.6 0.2 2.3 2 1 0 2 2 2 0 KR domain YCII PF03795.14 ABK70671.1 - 1.8e-09 37.9 0.0 2.2e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Glucosamine_iso PF01182.20 ABK70672.1 - 7.2e-23 81.6 0.0 1.1e-22 81.0 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Sugar-bind PF04198.13 ABK70672.1 - 0.0072 15.5 0.2 0.5 9.5 0.0 2.5 3 0 0 3 3 3 2 Putative sugar-binding domain Pribosyltran PF00156.27 ABK70672.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase domain Methyltrans_RNA PF04452.14 ABK70673.1 - 6.5e-65 218.6 0.0 7.4e-65 218.5 0.0 1.0 1 0 0 1 1 1 1 RNA methyltransferase Methyltrn_RNA_2 PF04013.12 ABK70673.1 - 0.025 14.3 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative SAM-dependent RNA methyltransferase DUF4350 PF14258.6 ABK70673.1 - 0.056 13.9 0.1 0.24 11.8 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4350) MlaD PF02470.20 ABK70674.1 - 6.1e-16 58.5 0.5 1.4e-15 57.4 0.5 1.6 1 0 0 1 1 1 1 MlaD protein YajC PF02699.15 ABK70674.1 - 0.0056 16.5 0.1 0.012 15.4 0.1 1.6 1 1 0 1 1 1 1 Preprotein translocase subunit NPV_P10 PF05531.12 ABK70674.1 - 0.0062 17.0 0.2 0.13 12.7 0.0 2.4 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein Bacillus_HBL PF05791.11 ABK70674.1 - 0.012 15.5 0.2 0.068 13.0 0.2 1.9 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) THDPS_N_2 PF14805.6 ABK70674.1 - 0.084 13.1 0.2 9.1 6.6 0.0 2.5 1 1 1 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Mce4_CUP1 PF11887.8 ABK70674.1 - 0.1 12.0 3.6 0.16 11.4 3.6 1.2 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative Glyoxalase_6 PF18029.1 ABK70675.1 - 4.9e-24 85.2 0.4 5.6e-24 85.0 0.4 1.0 1 0 0 1 1 1 1 Glyoxalase-like domain GCD14_N PF14801.6 ABK70675.1 - 0.0037 17.1 0.0 0.0084 15.9 0.0 1.6 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term TetR_N PF00440.23 ABK70676.1 - 2.3e-17 62.5 0.6 2.3e-17 62.5 0.6 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 ABK70676.1 - 2e-05 24.9 4.3 2e-05 24.9 2.2 2.1 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain AA_permease PF00324.21 ABK70677.1 - 1.1e-108 364.0 47.9 1.3e-108 363.7 47.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ABK70677.1 - 1.6e-38 132.7 52.1 1.8e-38 132.5 52.1 1.0 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.13 ABK70677.1 - 5.9e-11 41.8 19.9 5.9e-11 41.8 19.9 3.3 2 2 1 3 3 3 1 Spore germination protein DUF4133 PF13571.6 ABK70677.1 - 0.096 13.0 0.0 0.096 13.0 0.0 5.2 6 1 0 6 6 6 0 Domain of unknown function (DUF4133) p450 PF00067.22 ABK70678.1 - 2.9e-27 95.6 0.0 4.7e-25 88.3 0.0 2.8 1 1 0 1 1 1 1 Cytochrome P450 Methyltransf_5 PF01795.19 ABK70680.1 - 1e-115 386.5 0.0 1.1e-115 386.4 0.0 1.0 1 0 0 1 1 1 1 MraW methylase family Methyltransf_25 PF13649.6 ABK70680.1 - 0.03 15.0 0.0 0.2 12.4 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain rRNA_methylase PF06962.12 ABK70680.1 - 0.13 12.2 0.0 0.99 9.4 0.0 2.0 2 0 0 2 2 2 0 Putative rRNA methylase DUF4129 PF13559.6 ABK70680.1 - 0.97 9.7 7.1 2.3 8.5 0.2 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4129) MLTR_LBD PF17765.1 ABK70681.1 - 2.9e-45 154.4 2.8 6.1e-45 153.3 2.8 1.5 1 0 0 1 1 1 1 MmyB-like transcription regulator ligand binding domain HTH_31 PF13560.6 ABK70681.1 - 6.6e-15 55.2 6.7 2.1e-14 53.6 6.7 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 ABK70681.1 - 1.5e-05 24.9 0.0 3.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 ABK70681.1 - 0.14 12.6 0.0 0.38 11.2 0.0 1.7 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Lactamase_B_2 PF12706.7 ABK70682.1 - 6.3e-16 58.5 4.8 8.9e-16 58.0 4.8 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ABK70682.1 - 2.2e-14 53.9 8.7 4.2e-14 53.0 8.7 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF588 PF04535.12 ABK70683.1 - 0.034 14.0 1.5 0.034 14.0 1.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF588) TetR_N PF00440.23 ABK70684.1 - 2.7e-07 30.3 0.0 6.3e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_13 PF16925.5 ABK70684.1 - 2e-05 24.5 0.0 3.8e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain MTES_1575 PF18741.1 ABK70685.1 - 8.8e-08 32.2 0.0 1.5e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 REase_MTES_1575 DUF559 PF04480.12 ABK70685.1 - 0.0018 18.1 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF559) Bac_luciferase PF00296.20 ABK70686.1 - 1.1e-93 314.1 8.3 1.3e-93 313.9 8.3 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase AAA_16 PF13191.6 ABK70687.1 - 6.4e-15 55.9 1.8 6.4e-15 55.9 1.8 3.9 4 1 0 4 4 4 1 AAA ATPase domain GerE PF00196.19 ABK70687.1 - 2.6e-13 49.3 0.0 5.7e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family DUF2791 PF10923.8 ABK70687.1 - 0.00014 20.9 0.1 0.0003 19.8 0.1 1.5 1 0 0 1 1 1 1 P-loop Domain of unknown function (DUF2791) HTH_23 PF13384.6 ABK70687.1 - 0.00048 19.8 0.0 0.0024 17.6 0.0 2.2 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 ABK70687.1 - 0.026 14.2 0.1 0.2 11.3 0.0 2.7 3 0 0 3 3 3 0 Sigma-70, region 4 AAA_22 PF13401.6 ABK70687.1 - 0.038 14.3 0.0 0.26 11.6 0.0 2.4 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 ABK70687.1 - 0.088 12.7 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 NACHT domain cobW PF02492.19 ABK70687.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain HTH_24 PF13412.6 ABK70687.1 - 0.17 11.5 0.0 0.45 10.1 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Response_reg PF00072.24 ABK70689.1 - 1.3e-21 76.9 0.0 2.4e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 ABK70689.1 - 2.2e-16 59.1 0.1 3.7e-16 58.4 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 ABK70689.1 - 9.1e-08 31.7 0.2 2.2e-07 30.4 0.2 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_24 PF13412.6 ABK70689.1 - 0.0003 20.3 0.1 0.00076 19.0 0.1 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 ABK70689.1 - 0.00033 20.1 0.4 0.00089 18.7 0.4 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 ABK70689.1 - 0.001 18.8 0.1 0.0032 17.2 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 ABK70689.1 - 0.0024 17.2 0.0 0.018 14.5 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_40 PF14493.6 ABK70689.1 - 0.011 16.1 0.0 0.025 15.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.6 ABK70689.1 - 0.018 14.8 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 ABK70689.1 - 0.024 14.6 0.9 0.062 13.3 0.1 2.1 2 0 0 2 2 2 0 Winged helix-turn helix Arc_PepC PF06819.11 ABK70689.1 - 0.035 14.2 0.0 0.058 13.5 0.0 1.3 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminal Domain MarR_2 PF12802.7 ABK70689.1 - 0.084 12.8 0.6 1.3 9.0 0.2 2.5 2 0 0 2 2 2 0 MarR family HTH_28 PF13518.6 ABK70689.1 - 0.087 13.0 0.5 2.8 8.1 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain Glyoxalase PF00903.25 ABK70690.1 - 1.8e-07 31.4 0.1 4e-07 30.3 0.1 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 ABK70690.1 - 0.00016 21.6 0.0 0.00028 20.8 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 ABK70690.1 - 0.0016 19.2 0.1 0.0044 17.8 0.1 1.6 1 1 0 1 1 1 1 Glyoxalase-like domain BCCT PF02028.17 ABK70691.1 - 2.3e-182 606.8 42.0 2.7e-182 606.6 42.0 1.0 1 0 0 1 1 1 1 BCCT, betaine/carnitine/choline family transporter DUF3784 PF12650.7 ABK70691.1 - 0.2 11.9 0.1 0.2 11.9 0.1 5.4 5 2 1 6 6 6 0 Domain of unknown function (DUF3784) ABM PF03992.16 ABK70692.1 - 6.8e-16 58.2 0.1 9.2e-16 57.7 0.1 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF3364 PF11844.8 ABK70692.1 - 0.14 12.4 0.1 0.27 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3364) ABC_tran PF00005.27 ABK70693.1 - 5e-55 185.8 0.0 1.6e-30 106.4 0.0 2.2 2 0 0 2 2 2 2 ABC transporter oligo_HPY PF08352.12 ABK70693.1 - 6.1e-16 58.7 0.1 1.2e-07 32.2 0.0 2.9 3 0 0 3 3 2 2 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 ABK70693.1 - 3.2e-11 43.6 7.9 1e-05 25.5 0.0 4.1 2 2 2 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK70693.1 - 2.9e-10 39.9 0.0 0.00022 20.7 0.0 3.2 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ABK70693.1 - 9.7e-09 35.6 2.0 0.0033 17.7 0.1 3.5 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ABK70693.1 - 2.2e-07 31.4 5.0 0.0068 16.8 0.1 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 ABK70693.1 - 2.6e-05 23.9 0.4 0.21 11.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 ABK70693.1 - 0.00027 21.1 3.9 0.086 12.9 0.3 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_24 PF13479.6 ABK70693.1 - 0.0009 19.0 0.9 0.4 10.4 0.1 2.3 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 ABK70693.1 - 0.0038 17.2 0.1 2.2 8.2 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 ABK70693.1 - 0.0041 17.5 0.0 2.9 8.3 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF3987 PF13148.6 ABK70693.1 - 0.005 15.9 0.5 5.4 5.9 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3987) AAA_33 PF13671.6 ABK70693.1 - 0.0074 16.5 0.1 3.3 7.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ABK70693.1 - 0.0083 16.1 0.4 2 8.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.18 ABK70693.1 - 0.011 15.1 0.4 1.3 8.3 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.6 ABK70693.1 - 0.016 15.7 0.5 5 7.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ABK70693.1 - 0.017 14.6 0.4 3.4 7.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region PRK PF00485.18 ABK70693.1 - 0.023 14.4 0.5 2.5 7.8 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Mg_chelatase PF01078.21 ABK70693.1 - 0.046 13.1 0.0 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SbcCD_C PF13558.6 ABK70693.1 - 0.048 13.9 0.3 21 5.5 0.0 3.7 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 ABK70693.1 - 0.052 12.8 2.1 0.59 9.4 0.1 2.6 2 1 0 3 3 3 0 Zeta toxin ATP-synt_ab PF00006.25 ABK70693.1 - 0.054 13.1 0.1 1 9.0 0.0 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activat PF00158.26 ABK70693.1 - 0.058 13.1 3.4 3.6 7.2 0.1 2.6 3 0 0 3 3 2 0 Sigma-54 interaction domain NB-ARC PF00931.22 ABK70693.1 - 0.062 12.5 0.4 5.6 6.1 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain RsgA_GTPase PF03193.16 ABK70693.1 - 0.087 12.7 0.2 4.9 7.0 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_30 PF13604.6 ABK70693.1 - 0.1 12.3 2.0 2 8.1 0.2 2.7 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 ABK70693.1 - 0.1 12.3 0.2 4.9 6.8 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein ABC_ATPase PF09818.9 ABK70693.1 - 0.11 11.3 0.1 0.86 8.3 0.0 2.3 2 1 0 2 2 2 0 Predicted ATPase of the ABC class DUF927 PF06048.11 ABK70693.1 - 0.13 11.8 0.3 4.6 6.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF927) RNA_helicase PF00910.22 ABK70693.1 - 0.14 12.6 0.1 26 5.2 0.0 2.3 2 0 0 2 2 2 0 RNA helicase Msg2_C PF12373.8 ABK70693.1 - 0.14 11.6 0.1 0.39 10.2 0.1 1.7 1 0 0 1 1 1 0 Major surface glycoprotein 2 C terminal Herpes_ori_bp PF02399.15 ABK70693.1 - 0.34 8.9 0.1 4.2 5.3 0.0 2.0 2 0 0 2 2 2 0 Origin of replication binding protein polyprenyl_synt PF00348.17 ABK70694.1 - 7.8e-48 162.8 0.0 1.1e-47 162.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Lactamase_B PF00753.27 ABK70695.1 - 1.3e-18 67.8 7.1 8.1e-18 65.1 5.0 2.6 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 ABK70695.1 - 0.0002 21.3 0.1 0.00036 20.4 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 ABK70695.1 - 0.00025 20.6 0.4 0.00077 19.0 0.4 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Response_reg PF00072.24 ABK70696.1 - 5.6e-29 100.6 0.1 8.3e-29 100.0 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 ABK70696.1 - 4.2e-26 90.8 0.0 9.4e-26 89.7 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal DUF1869 PF08956.10 ABK70696.1 - 0.0035 17.2 0.0 0.012 15.5 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1869) Ribosomal_S21 PF01165.20 ABK70697.1 - 0.032 13.9 0.0 0.039 13.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S21 BPD_transp_1 PF00528.22 ABK70698.1 - 1.9e-11 44.0 14.9 1.9e-11 44.0 14.9 2.2 1 1 1 2 2 2 2 Binding-protein-dependent transport system inner membrane component Abhydrolase_6 PF12697.7 ABK70699.1 - 5.9e-14 53.2 15.6 7.4e-14 52.9 15.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ABK70699.1 - 1.5e-11 44.4 0.1 2.5e-08 33.9 0.1 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold S4_2 PF13275.6 ABK70700.1 - 2.1e-26 91.5 0.1 2.3e-26 91.4 0.1 1.0 1 0 0 1 1 1 1 S4 domain S4 PF01479.25 ABK70700.1 - 9.3e-05 22.1 0.1 0.00012 21.7 0.1 1.2 1 0 0 1 1 1 1 S4 domain NUDIX PF00293.28 ABK70701.1 - 2e-17 63.5 2.0 4e-17 62.5 0.7 1.9 2 0 0 2 2 2 1 NUDIX domain LemA PF04011.12 ABK70701.1 - 0.091 12.6 0.0 0.22 11.4 0.0 1.7 1 1 0 1 1 1 0 LemA family H_kinase_N PF12282.8 ABK70703.1 - 6.7e-46 155.8 0.4 2.2e-45 154.1 0.0 2.0 2 1 0 2 2 2 1 Signal transduction histidine kinase HisKA_2 PF07568.12 ABK70703.1 - 1.5e-22 79.4 3.7 3.4e-22 78.3 3.7 1.6 1 0 0 1 1 1 1 Histidine kinase HATPase_c PF02518.26 ABK70703.1 - 2e-09 37.9 0.1 8.6e-09 35.9 0.0 2.1 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HWE_HK PF07536.14 ABK70703.1 - 9.5e-09 35.8 1.8 2.2e-08 34.7 1.8 1.6 1 0 0 1 1 1 1 HWE histidine kinase HATPase_c_2 PF13581.6 ABK70703.1 - 8.9e-06 25.7 0.1 2.2e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PAS_4 PF08448.10 ABK70703.1 - 0.00015 22.0 0.7 0.0056 16.9 0.0 3.0 2 1 1 3 3 3 1 PAS fold HATPase_c_3 PF13589.6 ABK70703.1 - 0.073 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ABC_membrane PF00664.23 ABK70704.1 - 7.1e-39 134.1 9.8 8.9e-39 133.8 9.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 ABK70704.1 - 1.7e-26 93.4 0.0 3e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ABK70704.1 - 8.9e-05 22.0 0.2 0.0024 17.3 0.0 2.0 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain ABC_membrane_3 PF13748.6 ABK70704.1 - 9.3e-05 21.8 7.5 0.00069 18.9 1.5 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_22 PF13401.6 ABK70704.1 - 0.0043 17.3 0.1 0.056 13.7 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ABK70704.1 - 0.019 14.7 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ABK70704.1 - 0.021 14.7 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase DEAD PF00270.29 ABK70704.1 - 0.022 14.5 0.0 0.13 12.0 0.0 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA PF00004.29 ABK70704.1 - 0.033 14.6 0.0 0.48 10.9 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_membrane_2 PF06472.15 ABK70704.1 - 0.069 12.6 3.6 0.2 11.0 3.6 1.7 1 1 0 1 1 1 0 ABC transporter transmembrane region 2 AAA_16 PF13191.6 ABK70704.1 - 0.071 13.5 7.5 0.039 14.3 4.3 2.2 2 1 0 2 2 1 0 AAA ATPase domain SbcCD_C PF13558.6 ABK70704.1 - 0.085 13.1 0.3 1.7 8.9 0.3 2.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 ABK70704.1 - 0.091 12.0 1.4 0.24 10.7 0.3 2.2 2 1 1 3 3 3 0 Zeta toxin MMR_HSR1 PF01926.23 ABK70704.1 - 0.19 11.9 0.1 0.62 10.2 0.1 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF4577 PF15145.6 ABK70704.1 - 0.2 11.7 2.9 0.9 9.6 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4577) NB-ARC PF00931.22 ABK70704.1 - 0.2 10.8 0.0 0.54 9.4 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.6 ABK70704.1 - 1.5 8.5 7.1 0.46 10.2 3.1 2.2 2 1 0 2 2 1 0 AAA domain AAA_33 PF13671.6 ABK70704.1 - 3 8.0 4.9 0.79 9.9 0.1 2.5 3 0 0 3 3 3 0 AAA domain GrpE PF01025.19 ABK70705.1 - 4.1e-28 98.1 0.0 6.1e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 GrpE DUF2993 PF11209.8 ABK70706.1 - 3.1e-32 112.5 1.2 3.8e-32 112.3 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2993) Peptidase_M24 PF00557.24 ABK70707.1 - 7.5e-29 100.9 0.0 9.7e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 ABK70707.1 - 1.2e-27 97.1 0.0 2.3e-27 96.2 0.0 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain MerR_1 PF13411.6 ABK70708.1 - 4.1e-06 26.8 0.1 1.2e-05 25.3 0.0 1.9 2 0 0 2 2 2 1 MerR HTH family regulatory protein MerR-DNA-bind PF09278.11 ABK70708.1 - 0.027 15.0 0.3 0.22 12.1 0.0 2.8 2 0 0 2 2 2 0 MerR, DNA binding AAA_22 PF13401.6 ABK70708.1 - 0.063 13.6 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain TPR_2 PF07719.17 ABK70708.1 - 0.18 12.0 7.0 3.1 8.1 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 ABK70708.1 - 0.34 11.2 9.6 4.3 7.7 0.5 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_16 PF13191.6 ABK70708.1 - 1.1 9.7 10.9 0.058 13.8 1.2 3.6 2 2 1 3 3 3 0 AAA ATPase domain adh_short_C2 PF13561.6 ABK70709.1 - 5.3e-45 153.8 4.6 3.4e-44 151.2 4.6 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK70709.1 - 7.2e-41 139.8 0.2 3.9e-40 137.4 0.2 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK70709.1 - 7e-06 26.1 0.5 1.5e-05 25.0 0.5 1.5 1 1 0 1 1 1 1 KR domain Acyl-CoA_dh_2 PF08028.11 ABK70710.1 - 4.6e-16 59.3 9.4 4.6e-16 59.3 9.4 2.9 3 1 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK70710.1 - 3.3e-10 40.0 0.1 6.5e-10 39.1 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 ABK70710.1 - 7.7e-09 35.9 3.0 7.7e-09 35.9 3.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK70710.1 - 1.1e-07 32.4 0.1 2.9e-07 31.2 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain CysA_C_terminal PF17850.1 ABK70710.1 - 0.073 13.6 0.8 0.37 11.4 0.1 2.7 2 0 0 2 2 2 0 CysA C-terminal regulatory domain FUR PF01475.19 ABK70711.1 - 9.1e-05 22.6 0.0 0.00011 22.3 0.0 1.0 1 0 0 1 1 1 1 Ferric uptake regulator family HTH_12 PF08461.10 ABK70711.1 - 0.00077 19.4 0.0 0.00096 19.1 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain Peptidase_M15_3 PF08291.11 ABK70711.1 - 0.023 14.8 0.0 0.028 14.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase M15 adh_short PF00106.25 ABK70712.1 - 3.2e-30 105.0 0.1 4.2e-30 104.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK70712.1 - 1.2e-26 93.7 1.3 1.5e-26 93.4 1.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK70712.1 - 8.7e-10 38.8 0.4 1.4e-09 38.1 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK70712.1 - 1.1e-06 28.3 0.6 1.7e-05 24.4 0.6 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ABK70712.1 - 4.7e-06 26.6 1.6 7.3e-06 26.0 1.6 1.4 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 ABK70712.1 - 0.0024 17.0 0.4 0.0039 16.3 0.3 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain TetR_C_15 PF17918.1 ABK70712.1 - 0.039 14.7 0.7 0.43 11.4 0.1 2.5 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Orbi_VP4 PF05059.12 ABK70712.1 - 0.088 10.8 0.0 0.23 9.5 0.0 1.6 2 0 0 2 2 2 0 Orbivirus VP4 core protein Shikimate_DH PF01488.20 ABK70712.1 - 0.14 12.2 0.2 0.32 11.1 0.2 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.12 ABK70712.1 - 0.16 11.1 0.0 0.52 9.4 0.0 1.9 1 1 0 1 1 1 0 Male sterility protein Amidohydro_3 PF07969.11 ABK70713.1 - 2e-28 100.1 16.5 3.9e-26 92.6 16.5 2.2 1 1 0 1 1 1 1 Amidohydrolase family p450 PF00067.22 ABK70714.1 - 2.4e-27 95.8 0.0 4.7e-18 65.2 0.0 3.0 3 0 0 3 3 3 3 Cytochrome P450 TMEM252 PF15664.5 ABK70714.1 - 0.11 12.2 0.0 7.8 6.2 0.0 2.2 2 0 0 2 2 2 0 Transmembrane protein 252 family MFS_1 PF07690.16 ABK70715.1 - 4.1e-27 95.0 42.0 4.1e-27 95.0 42.0 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK70715.1 - 1.6e-23 83.3 5.7 1.6e-23 83.3 5.7 2.6 1 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.6 ABK70715.1 - 6.3e-10 38.2 22.9 6.3e-10 38.2 22.9 1.5 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_3 PF05977.13 ABK70715.1 - 1.9e-06 26.6 20.5 4.4e-05 22.1 0.6 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector LysM PF01476.20 ABK70716.1 - 2.1e-06 27.7 0.0 3.4e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 LysM domain ketoacyl-synt PF00109.26 ABK70717.1 - 4.5e-77 259.0 1.5 9.5e-77 258.0 0.2 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 ABK70717.1 - 2.4e-38 130.8 0.6 6.9e-37 126.1 0.7 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 ABK70717.1 - 4.5e-07 30.3 0.0 7.6e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 ABK70717.1 - 1.1e-05 24.9 0.1 4.7e-05 22.9 0.1 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain TetR_N PF00440.23 ABK70718.1 - 1.3e-14 53.7 0.1 3.4e-13 49.2 0.0 2.6 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_AsnC-type PF13404.6 ABK70718.1 - 4.2e-06 26.5 4.0 0.00068 19.4 0.3 3.3 3 1 0 3 3 2 2 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 ABK70718.1 - 0.00015 21.2 0.0 0.022 14.3 0.0 2.9 3 0 0 3 3 2 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 ABK70718.1 - 0.00016 21.4 0.7 0.00051 19.8 0.0 2.2 3 0 0 3 3 3 1 IclR helix-turn-helix domain HTH_23 PF13384.6 ABK70718.1 - 0.00023 20.9 0.2 0.0014 18.4 0.1 2.3 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 ABK70718.1 - 0.00043 20.1 5.5 0.16 11.9 0.0 3.7 3 1 0 3 3 3 2 MarR family LacI PF00356.21 ABK70718.1 - 0.00055 19.7 1.2 0.0024 17.6 0.0 2.7 4 0 0 4 4 4 1 Bacterial regulatory proteins, lacI family HTH_28 PF13518.6 ABK70718.1 - 0.00096 19.2 2.0 0.01 15.9 0.2 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_7 PF02796.15 ABK70718.1 - 0.0014 18.7 0.0 0.0062 16.6 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_22 PF13309.6 ABK70718.1 - 0.0018 18.3 0.1 0.19 11.8 0.0 2.7 2 0 0 2 2 2 1 HTH domain HTH_11 PF08279.12 ABK70718.1 - 0.0019 18.1 0.5 0.046 13.7 0.1 2.7 3 0 0 3 3 2 1 HTH domain Sigma70_r4 PF04545.16 ABK70718.1 - 0.0024 17.3 0.0 0.03 13.8 0.0 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_38 PF13936.6 ABK70718.1 - 0.0032 17.2 0.2 0.093 12.5 0.2 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 ABK70718.1 - 0.0074 16.3 0.3 0.62 10.2 0.0 3.0 3 0 0 3 3 3 1 Helix-turn-helix HTH_29 PF13551.6 ABK70718.1 - 0.01 15.9 0.2 0.032 14.3 0.2 1.8 1 0 0 1 1 1 0 Winged helix-turn helix HTH_AraC PF00165.23 ABK70718.1 - 0.018 15.2 0.0 0.45 10.7 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_Crp_2 PF13545.6 ABK70718.1 - 0.018 15.0 0.6 0.34 10.9 0.1 2.8 3 1 0 3 3 2 0 Crp-like helix-turn-helix domain TetR_C_36 PF18598.1 ABK70718.1 - 0.022 14.7 1.8 0.022 14.7 1.8 1.7 2 0 0 2 2 1 0 Tetracyclin repressor-like, C-terminal domain HTH_Tnp_ISL3 PF13542.6 ABK70718.1 - 0.024 14.1 0.2 0.25 10.8 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_17 PF12728.7 ABK70718.1 - 0.042 14.1 0.1 0.3 11.3 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 ABK70718.1 - 0.045 13.4 0.0 0.32 10.7 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_6 PF01418.17 ABK70718.1 - 0.081 12.9 0.0 1.7 8.7 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family UPF0122 PF04297.14 ABK70718.1 - 0.092 13.0 0.0 4.3 7.6 0.0 2.2 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like HTH_10 PF04967.12 ABK70718.1 - 0.11 12.4 0.0 0.6 10.0 0.0 2.2 2 0 0 2 2 2 0 HTH DNA binding domain HTH_Tnp_4 PF13613.6 ABK70718.1 - 0.12 12.2 0.0 0.34 10.7 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease TrmB PF01978.19 ABK70718.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB LZ_Tnp_IS481 PF13011.6 ABK70718.1 - 0.19 12.3 2.1 0.96 10.0 0.0 2.4 2 1 0 2 2 2 0 leucine-zipper of insertion element IS481 PEMT PF04191.13 ABK70719.1 - 2.4e-09 37.5 1.4 2.4e-09 37.5 1.4 2.5 3 1 0 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.14 ABK70719.1 - 2e-07 31.3 0.8 2e-07 31.3 0.8 2.0 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 ABK70719.1 - 0.04 12.7 0.4 0.085 11.6 0.0 1.7 1 1 1 2 2 2 0 Ergosterol biosynthesis ERG4/ERG24 family DUF3784 PF12650.7 ABK70719.1 - 7.3 6.9 13.5 1.7 8.9 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3784) DUF4440 PF14534.6 ABK70720.1 - 0.0008 19.8 0.0 0.0011 19.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 ABK70720.1 - 0.0012 19.5 0.1 0.0016 19.0 0.1 1.4 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 ABK70720.1 - 0.0031 17.7 0.1 0.0065 16.6 0.0 1.7 1 1 1 2 2 2 1 SnoaL-like domain SnoaL_3 PF13474.6 ABK70720.1 - 0.058 13.7 0.0 0.089 13.1 0.0 1.3 1 1 0 1 1 1 0 SnoaL-like domain Nitroreductase PF00881.24 ABK70721.1 - 2.4e-07 31.0 0.4 0.00066 19.8 0.0 3.0 2 1 1 3 3 3 2 Nitroreductase family TM1586_NiRdase PF14512.6 ABK70721.1 - 0.00042 20.0 0.0 0.015 14.8 0.0 2.1 2 0 0 2 2 2 2 Putative TM nitroreductase Cyt_bd_oxida_I PF01654.17 ABK70723.1 - 3.5e-162 539.8 26.6 3.9e-162 539.6 26.6 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit I DUF962 PF06127.11 ABK70723.1 - 3.3 7.8 10.7 1.3e+02 2.7 5.6 4.0 2 1 0 2 2 2 0 Protein of unknown function (DUF962) Beta_elim_lyase PF01212.21 ABK70724.1 - 4.8e-51 173.8 0.1 5.5e-51 173.6 0.1 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 ABK70724.1 - 0.00011 21.5 0.0 0.00013 21.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 ABK70724.1 - 0.00024 20.2 0.1 0.00031 19.8 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V SQS_PSY PF00494.19 ABK70725.1 - 8.6e-62 209.0 12.2 1e-61 208.8 12.2 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase Flavodoxin_2 PF02525.17 ABK70726.1 - 1.3e-48 165.4 0.0 1.5e-48 165.1 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 ABK70726.1 - 1.4e-08 34.6 0.0 4.6e-08 33.0 0.0 1.7 2 0 0 2 2 2 1 NADPH-dependent FMN reductase TraC PF07820.12 ABK70726.1 - 0.059 13.7 0.1 0.14 12.5 0.1 1.5 1 0 0 1 1 1 0 TraC-like protein Catalase PF00199.19 ABK70727.1 - 2.1e-164 547.2 0.0 2.7e-164 546.9 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 ABK70727.1 - 4.9e-20 71.5 0.5 2.7e-19 69.1 0.0 2.6 4 0 0 4 4 4 1 Catalase-related immune-responsive Aconitase PF00330.20 ABK70728.1 - 1e-74 252.3 1.0 2.2e-72 244.5 1.0 2.2 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) DUF521 PF04412.13 ABK70728.1 - 0.0002 20.2 0.0 0.00029 19.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF521) Response_reg PF00072.24 ABK70729.1 - 1.9e-24 86.0 0.2 2.6e-24 85.6 0.2 1.2 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 ABK70729.1 - 2.7e-17 62.0 0.1 6.4e-17 60.8 0.0 1.6 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 ABK70729.1 - 0.0011 18.6 0.1 0.013 15.2 0.0 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 ABK70729.1 - 0.006 16.1 0.3 0.018 14.5 0.1 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 E1_dh PF00676.20 ABK70730.1 - 1.1e-26 93.5 0.0 1.6e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 ABK70730.1 - 7.2e-21 74.7 0.0 1.5e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ABK70730.1 - 1.5e-19 70.1 0.2 1e-18 67.4 0.0 2.6 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 ABK70730.1 - 0.089 13.1 0.0 0.36 11.2 0.0 2.0 2 0 0 2 2 2 0 Pyruvate:ferredoxin oxidoreductase core domain II HpcH_HpaI PF03328.14 ABK70731.1 - 2.5e-17 62.8 0.0 3.1e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Abhydrolase_1 PF00561.20 ABK70732.1 - 2.7e-07 30.5 0.1 6.8e-07 29.2 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK70732.1 - 2.9e-06 28.0 15.0 4.4e-06 27.4 14.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK70732.1 - 0.00049 19.4 0.0 0.00078 18.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 TrbE PF11100.8 ABK70732.1 - 0.0015 18.7 0.3 0.0032 17.6 0.3 1.5 1 0 0 1 1 1 1 Conjugal transfer protein TrbE DUF202 PF02656.15 ABK70733.1 - 0.0068 16.8 5.5 0.018 15.5 0.2 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF202) PepSY_TM PF03929.16 ABK70733.1 - 0.13 11.9 2.9 0.12 12.1 2.9 1.2 1 1 0 1 1 1 0 PepSY-associated TM region SnoaL_4 PF13577.6 ABK70734.1 - 7.7e-20 71.3 0.5 1e-19 70.9 0.5 1.2 1 0 0 1 1 1 1 SnoaL-like domain Ring_hydroxyl_B PF00866.18 ABK70734.1 - 0.14 12.2 0.1 0.76 9.8 0.0 1.9 2 0 0 2 2 2 0 Ring hydroxylating beta subunit TetR_N PF00440.23 ABK70735.1 - 1.4e-15 56.8 0.1 3.8e-15 55.4 0.1 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family LacI PF00356.21 ABK70735.1 - 0.018 14.9 0.1 0.046 13.5 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family TetR_C_21 PF17926.1 ABK70735.1 - 0.02 15.1 0.2 0.056 13.6 0.1 1.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TetR_C_29 PF17938.1 ABK70735.1 - 0.021 14.9 0.0 0.094 12.8 0.0 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DprA_WH PF17782.1 ABK70735.1 - 0.045 13.9 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 DprA winged helix domain HTH_IclR PF09339.10 ABK70735.1 - 0.058 13.2 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_7 PF02796.15 ABK70735.1 - 0.11 12.6 0.0 0.4 10.8 0.0 1.9 1 1 1 2 2 2 0 Helix-turn-helix domain of resolvase HTH_40 PF14493.6 ABK70735.1 - 0.12 12.8 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain TetR_N PF00440.23 ABK70738.1 - 2.3e-10 40.1 0.0 2.3e-10 40.1 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_18 PF12833.7 ABK70738.1 - 0.0063 16.8 1.5 0.14 12.5 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain TetR_C_33 PF13305.6 ABK70738.1 - 0.39 11.5 9.3 0.31 11.8 4.9 2.7 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain BPD_transp_1 PF00528.22 ABK70739.1 - 4.9e-20 72.1 14.0 4.9e-20 72.1 14.0 1.7 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Dppa2_A PF14049.6 ABK70739.1 - 0.058 13.5 1.0 0.13 12.4 1.0 1.5 1 0 0 1 1 1 0 Dppa2/4 conserved region in higher vertebrates OppC_N PF12911.7 ABK70739.1 - 0.17 11.9 0.1 0.17 11.9 0.1 3.0 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C DUF3169 PF11368.8 ABK70739.1 - 0.2 11.2 0.6 0.38 10.2 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Aldedh PF00171.22 ABK70740.1 - 2.2e-139 464.9 0.0 2.5e-139 464.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PhoH PF02562.16 ABK70741.1 - 3.4e-95 317.3 0.1 4.5e-95 316.9 0.1 1.2 1 0 0 1 1 1 1 PhoH-like protein AAA_30 PF13604.6 ABK70741.1 - 6.9e-11 42.2 0.1 1.1e-10 41.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ABK70741.1 - 1.8e-07 31.6 0.4 8e-07 29.5 0.1 2.1 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 ABK70741.1 - 0.00058 19.6 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 ABK70741.1 - 0.002 18.4 0.9 0.024 14.9 0.3 2.8 1 1 1 2 2 2 1 AAA domain Zot PF05707.12 ABK70741.1 - 0.01 15.5 0.1 0.12 12.0 0.1 2.1 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) KH_1 PF00013.29 ABK70741.1 - 0.017 15.0 0.0 0.044 13.6 0.0 1.8 1 0 0 1 1 1 0 KH domain UvrD-helicase PF00580.21 ABK70741.1 - 0.018 14.6 0.9 4 6.9 0.1 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DEAD PF00270.29 ABK70741.1 - 0.019 14.7 0.1 0.44 10.3 0.1 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_25 PF13481.6 ABK70741.1 - 0.054 13.1 0.7 0.21 11.2 0.1 2.2 2 1 0 2 2 2 0 AAA domain CRCB PF02537.15 ABK70742.1 - 5.6e-26 90.7 5.6 6.8e-26 90.4 5.6 1.0 1 0 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) Ntox44 PF15607.6 ABK70742.1 - 0.094 13.0 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial toxin 44 DUF5500 PF17604.2 ABK70742.1 - 0.15 12.1 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5500) SPC12 PF06645.13 ABK70742.1 - 0.16 12.1 1.0 4.9 7.3 0.6 2.4 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) BtrH_N PF14399.6 ABK70744.1 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal Mce4_CUP1 PF11887.8 ABK70745.1 - 1.3e-100 336.1 0.0 1.6e-100 335.8 0.0 1.1 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative MlaD PF02470.20 ABK70745.1 - 3.6e-15 56.0 0.0 1.5e-13 50.8 0.0 2.4 2 0 0 2 2 2 1 MlaD protein SBP_bac_8 PF13416.6 ABK70746.1 - 3.8e-22 79.4 3.4 5e-22 79.0 3.4 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 ABK70746.1 - 3.4e-15 56.1 1.3 5e-15 55.6 1.3 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 ABK70746.1 - 3e-11 43.8 5.4 4.9e-11 43.1 5.4 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein DUF4013 PF13197.6 ABK70748.1 - 0.0051 16.7 17.3 0.0051 16.7 17.3 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF4013) Cytochrom_B_C PF00032.17 ABK70748.1 - 0.41 11.0 0.0 0.41 11.0 0.0 2.6 2 1 1 3 3 3 0 Cytochrome b(C-terminal)/b6/petD RibD_C PF01872.17 ABK70749.1 - 1e-13 51.6 0.0 1.8e-13 50.8 0.0 1.4 1 1 0 1 1 1 1 RibD C-terminal domain DUF1772 PF08592.11 ABK70750.1 - 1.7e-08 34.9 9.9 1.7e-08 34.9 9.9 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) DUF4131 PF13567.6 ABK70750.1 - 0.28 10.8 4.8 0.5 10.0 4.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF4175 PF13779.6 ABK70750.1 - 0.64 7.9 4.1 0.77 7.6 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) ABC_tran PF00005.27 ABK70751.1 - 1.3e-33 116.4 0.0 1.8e-33 116.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK70751.1 - 6.7e-13 49.1 0.0 5.7e-06 26.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK70751.1 - 7.2e-09 35.4 0.1 1.5e-07 31.1 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ABK70751.1 - 3.1e-05 24.6 0.0 5.3e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ABK70751.1 - 0.00024 20.8 0.0 0.00041 20.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 ABK70751.1 - 0.00068 19.4 0.0 0.0048 16.6 0.0 1.8 1 1 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 ABK70751.1 - 0.0012 19.3 0.4 0.002 18.6 0.4 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ABK70751.1 - 0.0013 19.0 0.1 0.0039 17.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ABK70751.1 - 0.0017 18.3 0.1 0.003 17.5 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase ABC_ATPase PF09818.9 ABK70751.1 - 0.0043 15.9 0.2 1.1 7.9 0.0 2.6 2 1 0 2 2 2 2 Predicted ATPase of the ABC class AAA_30 PF13604.6 ABK70751.1 - 0.0054 16.5 0.1 0.014 15.1 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 ABK70751.1 - 0.0075 16.4 0.1 0.012 15.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_13 PF13166.6 ABK70751.1 - 0.0094 14.7 0.0 0.34 9.5 0.0 2.0 1 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 ABK70751.1 - 0.011 15.7 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_25 PF13481.6 ABK70751.1 - 0.061 12.9 0.2 0.21 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 ABK70751.1 - 0.066 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 ABK70751.1 - 0.073 13.0 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 ABK70751.1 - 0.076 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain G-alpha PF00503.20 ABK70751.1 - 0.091 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_PrkA PF08298.11 ABK70751.1 - 0.092 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain SbcCD_C PF13558.6 ABK70751.1 - 0.1 12.8 0.1 1.3 9.3 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF1442 PF07279.11 ABK70751.1 - 0.15 11.4 0.1 0.32 10.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1442) adh_short_C2 PF13561.6 ABK70752.1 - 6.5e-47 160.0 0.0 8.1e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK70752.1 - 1.2e-45 155.3 0.0 1.6e-45 155.0 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK70752.1 - 5.6e-07 29.6 0.0 8e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 KR domain FeS_assembly_P PF01883.19 ABK70753.1 - 1.1e-16 60.8 0.1 3.8e-16 59.0 0.0 2.0 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein Germane PF10646.9 ABK70753.1 - 0.18 12.6 0.0 0.51 11.2 0.0 1.7 1 0 0 1 1 1 0 Sporulation and spore germination Pyr_redox_3 PF13738.6 ABK70754.1 - 4.1e-27 95.2 0.0 2.1e-26 92.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ABK70754.1 - 2.4e-11 43.4 0.0 4.3e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ABK70754.1 - 1.7e-10 40.5 0.7 6.3e-09 35.4 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 ABK70754.1 - 3.2e-09 36.5 5.2 7e-05 22.2 0.2 3.1 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.24 ABK70754.1 - 8.6e-08 32.1 5.4 0.0021 17.7 0.0 3.2 2 1 1 3 3 3 3 FAD dependent oxidoreductase FMO-like PF00743.19 ABK70754.1 - 1.5e-06 26.9 0.0 3.9e-06 25.6 0.0 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like HI0933_like PF03486.14 ABK70754.1 - 4.9e-05 22.2 1.3 1.4 7.5 0.2 3.1 3 0 0 3 3 3 2 HI0933-like protein Lycopene_cycl PF05834.12 ABK70754.1 - 0.00022 20.4 0.4 1.1 8.2 0.0 3.0 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox PF00070.27 ABK70754.1 - 0.00083 19.9 0.2 0.15 12.6 0.0 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ABK70754.1 - 0.00086 19.3 3.1 1.4 8.9 0.0 3.3 2 1 1 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 ABK70754.1 - 0.0014 18.8 0.1 1.8 8.8 0.1 2.9 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 ABK70754.1 - 0.0023 18.2 0.8 1.5 9.1 0.1 2.8 3 0 0 3 3 2 1 TrkA-N domain Shikimate_DH PF01488.20 ABK70754.1 - 0.0047 17.0 0.1 3.7 7.6 0.1 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 ABK70754.1 - 0.0084 15.2 0.6 0.63 9.1 0.0 2.8 3 0 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.17 ABK70754.1 - 0.017 14.4 0.0 4.6 6.4 0.0 2.3 2 0 0 2 2 2 0 Thi4 family ThiF PF00899.21 ABK70754.1 - 0.035 13.4 0.1 8.6 5.6 0.0 2.3 2 0 0 2 2 2 0 ThiF family NAD_binding_7 PF13241.6 ABK70754.1 - 0.094 13.2 0.0 5.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding ApbA PF02558.16 ABK70754.1 - 0.16 11.6 0.3 0.98 9.1 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 ABK70754.1 - 0.23 11.4 0.4 4.4 7.3 0.0 2.2 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 ABK70754.1 - 0.24 11.3 0.4 1.5 8.6 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 ABK70754.1 - 1.8 7.6 6.5 6.1 5.8 0.2 2.6 3 0 0 3 3 3 0 FAD binding domain ADH_N PF08240.12 ABK70755.1 - 1.3e-32 111.9 0.9 2.6e-32 110.9 0.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ABK70755.1 - 2.3e-20 72.9 0.5 3.8e-20 72.2 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ABK70755.1 - 1.4e-13 50.8 1.6 2.6e-13 50.0 1.6 1.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Pyr_redox_2 PF07992.14 ABK70755.1 - 0.0019 17.5 0.3 0.0032 16.7 0.3 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ABK70755.1 - 0.01 15.2 1.5 0.01 15.2 1.5 1.6 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ABK70755.1 - 0.059 12.7 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.21 ABK70755.1 - 0.15 11.4 0.2 0.41 10.0 0.2 1.7 1 0 0 1 1 1 0 ThiF family Pyr_redox_3 PF13738.6 ABK70755.1 - 0.17 11.1 1.0 0.29 10.3 1.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AdoHcyase_NAD PF00670.21 ABK70755.1 - 0.18 11.9 1.7 0.42 10.7 1.7 1.7 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Bac_luciferase PF00296.20 ABK70757.1 - 1e-44 153.3 13.1 1.2e-44 153.0 13.1 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Peripla_BP_3 PF13377.6 ABK70758.1 - 5.9e-45 153.6 3.7 7e-45 153.3 1.5 2.0 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 ABK70758.1 - 5.9e-18 65.3 0.0 8.1e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 ABK70758.1 - 1.6e-17 63.9 0.0 2.9e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein domain LacI PF00356.21 ABK70758.1 - 2.5e-12 46.4 2.0 1e-11 44.4 2.0 2.1 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family HTH_31 PF13560.6 ABK70758.1 - 0.0017 18.6 2.5 0.003 17.9 0.8 2.4 2 1 0 2 2 2 1 Helix-turn-helix domain DUF442 PF04273.13 ABK70758.1 - 0.03 14.4 0.6 4.7 7.3 0.1 2.7 1 1 1 2 2 2 0 Putative phosphatase (DUF442) PucR PF07905.11 ABK70758.1 - 0.044 14.1 0.1 0.19 12.0 0.0 2.1 2 1 0 2 2 2 0 Purine catabolism regulatory protein-like family HTH_IclR PF09339.10 ABK70759.1 - 2.8e-14 52.6 0.2 8.3e-14 51.1 0.2 1.9 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 ABK70759.1 - 1.2e-08 34.7 0.1 3.5e-08 33.2 0.1 1.8 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 ABK70759.1 - 6.9e-06 25.9 0.0 2.2e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB IclR PF01614.18 ABK70759.1 - 1e-05 25.4 0.1 2.6e-05 24.1 0.1 1.7 1 1 0 1 1 1 1 Bacterial transcriptional regulator MarR PF01047.22 ABK70759.1 - 0.0011 18.8 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 ABK70759.1 - 0.0044 17.3 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator HTH_24 PF13412.6 ABK70759.1 - 0.0079 15.7 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 ABK70759.1 - 0.011 15.6 0.1 0.027 14.3 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 ABK70759.1 - 0.012 15.6 1.6 0.1 12.7 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain DUF742 PF05331.11 ABK70759.1 - 0.014 15.2 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF742) HTH_47 PF16221.5 ABK70759.1 - 0.024 14.2 0.1 0.074 12.6 0.0 1.8 2 0 0 2 2 2 0 winged helix-turn-helix PadR PF03551.14 ABK70759.1 - 0.049 13.6 0.0 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family HTH_36 PF13730.6 ABK70759.1 - 0.12 12.4 0.0 0.5 10.4 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Penicillinase_R PF03965.16 ABK70759.1 - 0.14 12.5 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 Penicillinase repressor SnoaL_4 PF13577.6 ABK70760.1 - 2.7e-11 43.7 0.2 1.9e-10 40.9 0.2 2.0 1 1 0 1 1 1 1 SnoaL-like domain DUF3225 PF11533.8 ABK70760.1 - 0.0036 17.0 0.1 0.015 15.1 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3225) SnoaL_3 PF13474.6 ABK70760.1 - 0.11 12.7 0.0 0.56 10.5 0.0 1.9 2 0 0 2 2 2 0 SnoaL-like domain Response_reg PF00072.24 ABK70761.1 - 2e-18 66.6 0.1 4.5e-18 65.4 0.0 1.7 2 0 0 2 2 2 1 Response regulator receiver domain GerE PF00196.19 ABK70761.1 - 2.5e-14 52.6 0.2 6e-14 51.3 0.1 1.6 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 ABK70761.1 - 2.2e-06 27.2 0.0 3.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 ABK70761.1 - 0.0014 18.1 0.1 0.0035 16.8 0.1 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 KORA PF16509.5 ABK70761.1 - 0.0043 17.3 0.2 0.013 15.8 0.1 1.8 2 0 0 2 2 2 1 TrfB plasmid transcriptional repressor HTH_40 PF14493.6 ABK70761.1 - 0.02 15.3 0.1 0.051 14.0 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.6 ABK70761.1 - 0.024 14.4 0.1 0.061 13.1 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain MID_pPIWI_RE PF18157.1 ABK70761.1 - 0.041 14.2 0.1 0.54 10.5 0.0 2.2 2 1 0 2 2 2 0 MID domain of pPIWI_RE NanE PF04131.14 ABK70761.1 - 0.081 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase PPE PF00823.19 ABK70762.1 - 4.5e-50 169.8 17.0 4.5e-50 169.8 17.0 2.5 2 1 1 3 3 3 1 PPE family Sugar_tr PF00083.24 ABK70763.1 - 3.9e-57 194.1 12.8 4.4e-57 193.9 12.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ABK70763.1 - 0.00015 20.9 31.0 0.00032 19.8 29.2 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily CEND1 PF15677.5 ABK70763.1 - 1.1 9.8 7.7 0.28 11.7 4.0 1.8 1 1 1 2 2 2 0 Cell cycle exit and neuronal differentiation protein 1 Peptidase_M24 PF00557.24 ABK70764.1 - 1e-34 120.1 0.0 1.5e-34 119.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 ABK70764.1 - 1.1e-08 35.8 0.0 2.4e-08 34.7 0.0 1.6 1 1 0 1 1 1 1 Creatinase/Prolidase N-terminal domain DUF4880 PF16220.5 ABK70764.1 - 0.7 9.8 3.1 0.45 10.5 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4880) Amidohydro_2 PF04909.14 ABK70765.1 - 9.5e-17 61.7 9.0 1e-09 38.6 3.5 2.1 1 1 1 2 2 2 2 Amidohydrolase RPE65 PF03055.15 ABK70766.1 - 3e-106 356.4 0.1 3.4e-106 356.2 0.1 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein CHAP PF05257.16 ABK70766.1 - 0.068 13.7 0.2 0.18 12.4 0.2 1.7 1 0 0 1 1 1 0 CHAP domain Lysine_decarbox PF03641.14 ABK70767.1 - 1.2e-37 128.9 0.0 1.5e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 ABK70767.1 - 8.2e-21 74.2 0.0 1e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 SLOG cluster4 family DNA_processg_A PF02481.15 ABK70767.1 - 0.08 12.2 0.2 0.098 11.9 0.2 1.2 1 0 0 1 1 1 0 DNA recombination-mediator protein A AMP-binding PF00501.28 ABK70768.1 - 4.5e-67 226.5 0.0 6e-67 226.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK70768.1 - 8.1e-10 39.6 0.2 1.9e-09 38.4 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RPE65 PF03055.15 ABK70769.1 - 3.7e-108 362.7 0.0 4.2e-108 362.5 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein AIRS PF00586.24 ABK70770.1 - 2.9e-15 56.7 1.3 7.8e-15 55.3 1.3 1.7 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Acetyltransf_10 PF13673.7 ABK70770.1 - 5.8e-06 26.3 0.0 8.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AIRS_C PF02769.22 ABK70770.1 - 7.3e-06 26.2 0.2 1.3e-05 25.4 0.2 1.4 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain Acetyltransf_1 PF00583.25 ABK70770.1 - 5.9e-05 23.3 0.0 0.00011 22.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ABK70770.1 - 0.033 14.6 0.0 0.063 13.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acyl-CoA_dh_1 PF00441.24 ABK70771.1 - 3.2e-31 108.6 6.8 5.6e-31 107.8 6.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK70771.1 - 1.7e-13 50.6 0.0 3e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ABK70771.1 - 1.5e-06 28.9 0.3 6.5e-06 26.8 0.0 2.2 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ABK70771.1 - 1.2e-05 25.6 0.6 5.8e-05 23.4 0.3 2.2 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Dynamin_N PF00350.23 ABK70772.1 - 5.8e-10 39.5 0.0 4.7e-08 33.3 0.0 2.2 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 ABK70772.1 - 3.6e-07 30.3 0.0 8.2e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ABK70772.1 - 0.0063 16.4 0.0 0.2 11.6 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 ABK70772.1 - 0.02 14.4 0.1 0.97 8.9 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AIG1 PF04548.16 ABK70772.1 - 0.026 13.8 0.0 6.6 6.0 0.0 2.3 2 0 0 2 2 2 0 AIG1 family ABC_tran PF00005.27 ABK70772.1 - 0.05 14.1 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.27 ABK70772.1 - 0.14 11.7 0.0 0.62 9.6 0.0 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain IIGP PF05049.13 ABK70772.1 - 0.15 11.1 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) HTH_20 PF12840.7 ABK70773.1 - 6e-14 51.9 1.6 1e-13 51.1 1.6 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain AHSA1 PF08327.11 ABK70773.1 - 8.1e-11 42.2 0.0 1.3e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein MarR_2 PF12802.7 ABK70773.1 - 5.2e-08 32.6 0.9 1.5e-07 31.2 0.6 1.8 1 1 1 2 2 2 1 MarR family HTH_5 PF01022.20 ABK70773.1 - 0.00044 20.1 0.1 0.00081 19.2 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 ABK70773.1 - 0.00075 19.0 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 ABK70773.1 - 0.007 16.1 0.8 0.023 14.5 0.8 1.9 1 1 0 1 1 1 1 IclR helix-turn-helix domain DprA_WH PF17782.1 ABK70773.1 - 0.016 15.3 1.4 0.036 14.2 1.4 1.6 1 0 0 1 1 1 0 DprA winged helix domain MarR PF01047.22 ABK70773.1 - 0.021 14.7 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 MarR family DUF4486 PF14858.6 ABK70773.1 - 0.021 13.3 0.1 0.026 13.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4486) HTH_27 PF13463.6 ABK70773.1 - 0.029 14.9 0.1 0.061 13.8 0.1 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain BLACT_WH PF17778.1 ABK70773.1 - 0.093 12.7 1.7 0.6 10.1 0.3 2.4 2 0 0 2 2 2 0 Beta-lactamase associated winged helix domain GntR PF00392.21 ABK70773.1 - 0.11 12.1 0.3 0.25 11.0 0.3 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_41 PF14502.6 ABK70773.1 - 0.12 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.12 ABK70773.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 HTH domain PRiA4_ORF3 PF07929.11 ABK70774.1 - 1.4e-51 174.6 0.0 1.7e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein FMN_dh PF01070.18 ABK70775.1 - 3e-13 49.5 1.7 5.6e-07 28.9 0.0 2.2 2 0 0 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.25 ABK70775.1 - 0.05 12.6 2.1 0.39 9.7 0.0 2.2 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 ABK70775.1 - 0.055 12.6 0.3 2.1 7.4 0.1 2.1 2 0 0 2 2 2 0 Conserved region in glutamate synthase DHO_dh PF01180.21 ABK70775.1 - 0.067 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase LysE PF01810.18 ABK70776.1 - 7.1e-47 159.4 10.1 8.1e-47 159.2 10.1 1.0 1 0 0 1 1 1 1 LysE type translocator DUF5632 PF18646.1 ABK70776.1 - 0.013 15.6 0.1 0.024 14.7 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5632) TetR_N PF00440.23 ABK70777.1 - 5.9e-13 48.4 0.7 4.4e-12 45.6 0.1 2.3 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 ABK70777.1 - 0.00076 19.8 2.1 0.0014 18.9 2.0 1.6 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_6 PF13977.6 ABK70777.1 - 0.0025 18.0 0.8 0.0025 18.0 0.8 1.7 2 0 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal TetR_C_13 PF16925.5 ABK70777.1 - 0.013 15.4 0.0 0.032 14.2 0.0 1.7 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TetR_C_33 PF13305.6 ABK70777.1 - 0.26 12.0 3.2 0.66 10.7 3.2 1.9 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain ABC_tran PF00005.27 ABK70778.1 - 1.7e-31 109.5 0.0 2.5e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 ABK70778.1 - 3.8e-06 26.9 0.0 8.6e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 ABK70778.1 - 1.2e-05 25.2 0.3 0.0088 15.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ABK70778.1 - 5.7e-05 23.6 0.1 7.6e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 ABK70778.1 - 0.00052 19.8 0.0 0.012 15.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 ABK70778.1 - 0.00089 18.9 0.8 0.066 12.8 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ABK70778.1 - 0.00098 19.4 0.0 0.0021 18.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 ABK70778.1 - 0.001 19.1 0.0 0.0015 18.5 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_29 PF13555.6 ABK70778.1 - 0.0038 16.9 0.1 0.009 15.7 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 ABK70778.1 - 0.0046 17.4 0.0 0.026 15.0 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 ABK70778.1 - 0.013 15.5 0.2 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 NTPase ATPase_2 PF01637.18 ABK70778.1 - 0.015 15.2 0.0 0.086 12.7 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 ABK70778.1 - 0.019 15.5 0.0 0.026 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ABK70778.1 - 0.02 14.2 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ABC_ATPase PF09818.9 ABK70778.1 - 0.029 13.2 0.1 1.6 7.4 0.0 2.4 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_33 PF13671.6 ABK70778.1 - 0.046 13.9 0.1 0.095 12.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 ABK70778.1 - 0.048 12.8 0.1 0.095 11.9 0.1 1.5 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.6 ABK70778.1 - 0.077 13.2 0.0 0.82 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ABK70778.1 - 0.099 12.6 0.2 0.19 11.6 0.2 1.4 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 ABK70778.1 - 0.14 12.7 0.0 0.28 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ABK70778.1 - 0.19 12.2 0.0 0.37 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Viral_helicase1 PF01443.18 ABK70778.1 - 0.19 11.4 0.2 1.9 8.1 0.4 2.1 1 1 1 2 2 2 0 Viral (Superfamily 1) RNA helicase PRK PF00485.18 ABK70778.1 - 0.2 11.4 0.4 0.36 10.5 0.4 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family SMC_N PF02463.19 ABK70778.1 - 0.24 10.8 0.0 0.96 8.8 0.0 1.8 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain OsmC PF02566.19 ABK70779.1 - 1.7e-19 70.1 0.0 2.3e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 OsmC-like protein Glyco_hydro_3 PF00933.21 ABK70781.1 - 1.5e-74 251.3 0.0 4.7e-74 249.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 ABK70781.1 - 3e-40 138.4 0.0 5.4e-40 137.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 ABK70781.1 - 7.4e-16 58.0 0.1 1.5e-15 57.0 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain COX3 PF00510.18 ABK70782.1 - 4.4e-13 49.7 10.9 6.9e-13 49.0 10.9 1.3 1 1 0 1 1 1 1 Cytochrome c oxidase subunit III Lipase_GDSL_2 PF13472.6 ABK70783.1 - 8.3e-19 68.7 0.0 9.8e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ABK70783.1 - 2.4e-10 40.7 0.0 4.5e-10 39.8 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DoxX PF07681.12 ABK70784.1 - 2.7e-14 53.5 12.4 2.7e-14 53.5 12.4 2.5 1 1 1 2 2 2 1 DoxX DoxX_2 PF13564.6 ABK70784.1 - 6e-05 23.1 13.3 6e-05 23.1 13.3 2.1 2 0 0 2 2 2 1 DoxX-like family DoxD PF04173.13 ABK70784.1 - 9.2e-05 22.4 3.0 0.0011 19.0 0.8 2.1 2 0 0 2 2 2 1 TQO small subunit DoxD DUF2613 PF11021.8 ABK70784.1 - 2.3 8.4 8.1 6.5 7.0 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Usp PF00582.26 ABK70785.1 - 8.2e-22 78.2 5.1 1.7e-21 77.2 5.1 1.5 1 1 0 1 1 1 1 Universal stress protein family adh_short_C2 PF13561.6 ABK70786.1 - 1.5e-61 208.0 0.5 1.8e-61 207.7 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK70786.1 - 3.1e-47 160.6 0.0 3.9e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK70786.1 - 4.7e-11 42.9 0.1 6.9e-11 42.4 0.1 1.2 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 ABK70786.1 - 0.014 15.4 0.2 0.026 14.5 0.2 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Glyco_trans_4_4 PF13579.6 ABK70786.1 - 0.034 14.6 2.3 0.046 14.2 0.5 1.9 1 1 1 2 2 2 0 Glycosyl transferase 4-like domain 2-Hacid_dh_C PF02826.19 ABK70786.1 - 0.039 13.3 0.1 0.061 12.7 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.8 ABK70786.1 - 0.039 13.7 0.3 0.08 12.7 0.3 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.20 ABK70786.1 - 0.094 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 ABK70786.1 - 0.1 12.0 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ABK70786.1 - 0.12 12.2 2.0 0.13 12.1 0.1 2.0 2 1 0 2 2 2 0 NAD(P)H-binding NAD_binding_7 PF13241.6 ABK70786.1 - 0.13 12.7 0.0 0.39 11.2 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 ABK70786.1 - 0.15 12.0 0.2 0.29 11.0 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_hydro_3_C PF01915.22 ABK70786.1 - 0.17 11.8 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain NLPC_P60 PF00877.19 ABK70787.1 - 1.5e-17 63.5 0.0 2.1e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 NlpC/P60 family ABC_tran_CTD PF16326.5 ABK70787.1 - 0.019 15.2 2.9 0.047 13.9 2.9 1.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain CHAP PF05257.16 ABK70787.1 - 0.07 13.7 0.1 0.23 12.0 0.1 1.9 2 0 0 2 2 2 0 CHAP domain WXG100 PF06013.12 ABK70787.1 - 0.59 10.4 6.9 0.27 11.5 3.2 2.2 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Med9 PF07544.13 ABK70788.1 - 0.14 12.2 0.2 0.21 11.7 0.2 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 TAS2R PF05296.13 ABK70789.1 - 0.0018 17.4 0.3 0.0019 17.4 0.3 1.0 1 0 0 1 1 1 1 Taste receptor protein (TAS2R) Transgly PF00912.22 ABK70790.1 - 6.9e-55 185.3 0.1 1.2e-54 184.4 0.1 1.4 1 0 0 1 1 1 1 Transglycosylase Transpeptidase PF00905.22 ABK70790.1 - 1.7e-21 76.7 0.1 4.1e-21 75.5 0.1 1.5 1 1 0 1 1 1 1 Penicillin binding protein transpeptidase domain PASTA PF03793.19 ABK70790.1 - 1.4e-09 37.7 0.3 5.7e-09 35.7 0.3 2.2 1 0 0 1 1 1 1 PASTA domain Peptidase_M20 PF01546.28 ABK70791.1 - 1.2e-24 87.2 0.2 1.5e-24 86.8 0.2 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ABK70791.1 - 0.14 12.1 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Peptidase dimerisation domain Peptidase_M28 PF04389.17 ABK70791.1 - 0.14 11.8 0.1 0.24 11.1 0.1 1.3 1 0 0 1 1 1 0 Peptidase family M28 ABC_tran PF00005.27 ABK70794.1 - 6.6e-32 110.9 0.0 1.7e-31 109.5 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 ABK70794.1 - 1.7e-05 24.8 0.0 0.0009 19.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 ABK70794.1 - 0.0035 17.8 0.0 0.015 15.7 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ABK70794.1 - 0.0065 16.8 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ABK70794.1 - 0.018 15.4 0.0 0.036 14.5 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 ABK70794.1 - 0.04 13.6 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 ABK70794.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 ABK70794.1 - 0.14 11.9 0.1 1.5 8.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ABK70794.1 - 0.24 10.9 0.0 0.36 10.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Proteasome PF00227.26 ABK70795.1 - 1.2e-41 142.3 0.0 1.4e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF1802 PF08819.11 ABK70796.1 - 5.6e-61 205.4 0.1 6.3e-61 205.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1802) DUF4995 PF16386.5 ABK70797.1 - 0.13 12.3 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function RibD_C PF01872.17 ABK70798.1 - 3.6e-10 40.0 0.0 6.1e-10 39.3 0.0 1.5 1 1 0 1 1 1 1 RibD C-terminal domain GAS2 PF02187.17 ABK70798.1 - 0.14 12.3 0.0 0.35 11.0 0.0 1.6 2 0 0 2 2 2 0 Growth-Arrest-Specific Protein 2 Domain Ribosomal_L12 PF00542.19 ABK70799.1 - 7.2e-28 96.7 6.8 7.2e-28 96.7 6.8 1.9 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 ABK70799.1 - 5.9e-20 70.7 12.2 5.4e-19 67.6 9.5 2.5 2 0 0 2 2 2 2 Ribosomal protein L7/L12 dimerisation domain TetR_N PF00440.23 ABK70800.1 - 4e-11 42.5 0.1 9.9e-11 41.3 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_31 PF17940.1 ABK70800.1 - 0.00024 21.2 7.1 0.00066 19.9 1.5 2.6 3 0 0 3 3 3 1 Tetracyclin repressor-like, C-terminal domain TetR_C_6 PF13977.6 ABK70800.1 - 0.034 14.4 0.3 0.034 14.4 0.3 2.3 2 1 1 3 3 3 0 BetI-type transcriptional repressor, C-terminal WzyE PF06899.11 ABK70800.1 - 0.17 10.8 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 WzyE protein, O-antigen assembly polymerase GATase_3 PF07685.14 ABK70801.1 - 4.1e-41 140.8 0.0 6.7e-41 140.1 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.23 ABK70801.1 - 3.1e-22 79.0 0.0 6.3e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 ABK70801.1 - 6.9e-14 52.1 0.0 2.9e-13 50.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain SNO PF01174.19 ABK70801.1 - 0.027 14.3 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 SNO glutamine amidotransferase family GATase PF00117.28 ABK70801.1 - 0.058 13.2 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase class-I DD_K PF12121.8 ABK70801.1 - 0.11 12.6 5.5 7 6.9 3.3 2.7 2 0 0 2 2 2 0 Dermaseptin MobB PF03205.14 ABK70801.1 - 0.19 11.6 0.1 1.4 8.8 0.0 2.4 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B PRiA4_ORF3 PF07929.11 ABK70802.1 - 2.1e-51 174.1 0.0 2.5e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein Chlorophyllase2 PF12740.7 ABK70804.1 - 0.0095 14.9 0.0 0.019 13.9 0.0 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 ABK70804.1 - 0.082 11.9 0.1 0.12 11.3 0.1 1.3 1 0 0 1 1 1 0 Chlorophyllase AP_endonuc_2 PF01261.24 ABK70805.1 - 2.2e-26 92.6 0.0 3.2e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel HTH_19 PF12844.7 ABK70805.1 - 0.067 13.2 0.0 0.24 11.5 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Fer2 PF00111.27 ABK70806.1 - 1.7e-12 47.1 0.2 2.9e-12 46.4 0.2 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.21 ABK70806.1 - 2.1e-05 25.1 0.1 0.0085 16.7 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain Fer2_4 PF13510.6 ABK70806.1 - 0.0012 18.9 0.1 0.0049 16.9 0.0 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_6 PF08030.12 ABK70806.1 - 0.14 12.3 0.1 0.72 10.0 0.0 1.9 2 0 0 2 2 2 0 Ferric reductase NAD binding domain TPP_enzyme_N PF02776.18 ABK70807.1 - 6.2e-46 156.1 3.5 9.2e-43 145.8 0.7 3.0 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 ABK70807.1 - 2.4e-29 102.1 0.8 1.1e-25 90.2 0.1 2.8 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 ABK70807.1 - 3.3e-25 88.4 1.8 6.8e-25 87.4 0.0 2.4 4 0 0 4 4 4 1 Thiamine pyrophosphate enzyme, central domain Formyl_trans_N PF00551.19 ABK70808.1 - 6e-32 110.8 0.0 7.1e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 ABK70808.1 - 2.8e-22 78.8 0.0 4.1e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain 2-Hacid_dh_C PF02826.19 ABK70809.1 - 7.8e-52 175.2 0.0 1e-51 174.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ABK70809.1 - 2.4e-22 79.1 0.0 2.9e-22 78.8 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain HD PF01966.22 ABK70812.1 - 7.2e-05 23.0 0.5 0.00012 22.3 0.5 1.4 1 1 0 1 1 1 1 HD domain DUF3323 PF11796.8 ABK70812.1 - 0.012 15.5 0.4 0.016 15.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) Acyl-CoA_dh_2 PF08028.11 ABK70813.1 - 1.1e-15 58.0 6.7 2.6e-15 56.9 6.7 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.24 ABK70813.1 - 4.3e-11 43.2 1.0 7.5e-11 42.4 1.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK70813.1 - 1.9e-10 41.4 0.1 5.3e-10 40.0 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ABK70813.1 - 1.7e-08 34.6 0.0 3.6e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain MoeA_N PF03453.17 ABK70814.1 - 7.1e-46 155.8 7.9 1.7e-45 154.6 7.5 1.8 2 0 0 2 2 2 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 ABK70814.1 - 3.2e-22 78.8 0.4 6.4e-22 77.8 0.2 1.5 2 0 0 2 2 2 1 Probable molybdopterin binding domain MoeA_C PF03454.15 ABK70814.1 - 1.2e-16 60.6 0.0 6.2e-16 58.3 0.0 2.3 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) Mrr_cat PF04471.12 ABK70814.1 - 0.065 13.3 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Restriction endonuclease CstA PF02554.14 ABK70816.1 - 9.3e-165 548.1 24.9 9.3e-165 548.1 24.9 1.9 2 0 0 2 2 2 1 Carbon starvation protein CstA CstA_5TM PF13722.6 ABK70816.1 - 2.8e-32 111.5 6.2 2.8e-32 111.5 6.2 3.3 4 0 0 4 4 4 1 5TM C-terminal transporter carbon starvation CstA HIG_1_N PF04588.13 ABK70816.1 - 0.3 11.4 0.1 0.3 11.4 0.1 4.3 5 0 0 5 5 5 0 Hypoxia induced protein conserved region DUF3418 PF11898.8 ABK70817.1 - 1.3e-213 710.9 4.6 1.8e-213 710.4 4.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3418) OB_NTP_bind PF07717.16 ABK70817.1 - 8e-16 58.2 0.0 1.5e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 ABK70817.1 - 1.4e-14 54.3 0.0 3e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 ABK70817.1 - 2.8e-11 43.7 0.0 5.6e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ABK70817.1 - 1.9e-05 24.5 0.1 5.1e-05 23.1 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 ABK70817.1 - 0.00021 21.7 0.0 0.00065 20.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 ABK70817.1 - 0.00029 20.0 0.0 0.00061 18.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 ABK70817.1 - 0.001 19.3 0.1 0.0034 17.6 0.1 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 ABK70817.1 - 0.01 15.8 1.1 0.084 12.8 1.1 2.5 1 1 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 ABK70817.1 - 0.018 14.8 1.7 0.04 13.6 0.2 2.3 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 ABK70817.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 ABK70817.1 - 0.11 11.9 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 ABK70817.1 - 0.18 12.3 0.0 0.57 10.7 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Acetyltransf_17 PF17668.1 ABK70818.1 - 5e-24 85.4 0.3 9.7e-24 84.4 0.3 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ABK70818.1 - 1.3e-20 73.8 0.0 2e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SCP2_2 PF13530.6 ABK70818.1 - 1.2e-13 51.3 0.0 2.7e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Sterol carrier protein domain Acetyltransf_10 PF13673.7 ABK70818.1 - 1e-05 25.4 0.0 1.8e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ABK70818.1 - 1.2e-05 25.6 0.0 2.6e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ABK70818.1 - 0.00011 22.4 0.0 0.00022 21.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 ABK70818.1 - 0.00023 21.2 0.2 0.00085 19.4 0.1 1.9 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 ABK70818.1 - 0.0062 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein DAO PF01266.24 ABK70819.1 - 2.5e-49 168.8 5.6 3.8e-49 168.1 5.6 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 ABK70819.1 - 4.6e-30 104.1 0.0 1.1e-29 102.8 0.0 1.7 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_oxidored PF12831.7 ABK70819.1 - 5.3e-12 45.8 2.3 2.3e-08 33.9 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ABK70819.1 - 3.6e-10 39.5 12.2 3.9e-06 26.2 1.5 2.5 3 0 0 3 3 3 2 FAD binding domain FAD_binding_3 PF01494.19 ABK70819.1 - 6.1e-09 35.6 2.3 2.9e-08 33.4 2.3 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ABK70819.1 - 8e-06 25.3 0.2 4e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ABK70819.1 - 0.00039 19.6 0.9 0.00039 19.6 0.9 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 ABK70819.1 - 0.0025 18.0 1.1 0.0094 16.2 1.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 ABK70819.1 - 0.0029 16.9 0.1 0.0066 15.8 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 ABK70819.1 - 0.003 17.5 0.1 0.006 16.5 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 ABK70819.1 - 0.013 14.2 1.6 0.022 13.5 1.6 1.3 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 ABK70819.1 - 0.014 14.6 0.4 0.014 14.6 0.4 2.0 2 1 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 ABK70819.1 - 0.02 15.5 1.3 0.02 15.5 1.3 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ABK70819.1 - 0.49 9.4 5.8 0.46 9.5 0.1 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein Trp_halogenase PF04820.14 ABK70819.1 - 2.5 6.9 5.6 13 4.5 1.6 2.1 2 0 0 2 2 2 0 Tryptophan halogenase IstB_IS21 PF01695.17 ABK70820.1 - 9.6e-55 185.1 0.0 1.4e-54 184.5 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_30 PF13604.6 ABK70820.1 - 1.8e-07 31.1 0.1 2.4e-06 27.4 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA PF00004.29 ABK70820.1 - 5.7e-05 23.5 0.0 0.00014 22.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ABK70820.1 - 0.00028 21.2 0.2 0.028 14.7 0.1 3.1 2 2 1 3 3 3 1 AAA domain AAA_5 PF07728.14 ABK70820.1 - 0.00034 20.6 0.0 0.00069 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.23 ABK70820.1 - 0.0022 17.1 0.0 0.0033 16.6 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain AAA_33 PF13671.6 ABK70820.1 - 0.0033 17.6 2.5 0.011 15.9 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 ABK70820.1 - 0.0041 16.7 2.2 0.023 14.3 0.2 2.6 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 ABK70820.1 - 0.0061 17.1 0.0 0.012 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ABK70820.1 - 0.0069 16.7 0.9 0.021 15.2 0.3 2.2 1 1 1 2 2 2 1 AAA domain AAA_11 PF13086.6 ABK70820.1 - 0.0069 16.2 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 ABK70820.1 - 0.0079 15.4 0.0 0.051 12.8 0.0 1.9 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_16 PF13191.6 ABK70820.1 - 0.008 16.6 4.9 0.0092 16.4 0.1 2.8 1 1 2 3 3 3 1 AAA ATPase domain AAA_28 PF13521.6 ABK70820.1 - 0.012 15.9 0.8 0.028 14.6 0.1 2.0 2 1 0 2 2 2 0 AAA domain CbiA PF01656.23 ABK70820.1 - 0.013 15.5 0.1 0.027 14.5 0.1 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain TACC_C PF05010.14 ABK70820.1 - 0.023 14.5 0.4 0.035 13.9 0.4 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal AAA_7 PF12775.7 ABK70820.1 - 0.026 14.1 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RuvB_N PF05496.12 ABK70820.1 - 0.03 14.1 0.0 0.052 13.3 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 ABK70820.1 - 0.032 14.2 0.1 0.37 10.7 0.0 2.2 1 1 1 2 2 2 0 NACHT domain PhoH PF02562.16 ABK70820.1 - 0.042 13.3 0.1 0.08 12.4 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 ABK70820.1 - 0.045 13.1 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 KaiC TsaE PF02367.17 ABK70820.1 - 0.046 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 ABK70820.1 - 0.052 13.4 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_24 PF13479.6 ABK70820.1 - 0.055 13.2 0.0 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ABK70820.1 - 0.056 13.8 0.0 0.15 12.5 0.0 1.7 1 1 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 ABK70820.1 - 0.068 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI 6PF2K PF01591.18 ABK70820.1 - 0.08 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase hemP PF10636.9 ABK70820.1 - 0.087 12.6 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 Hemin uptake protein hemP AAA_3 PF07726.11 ABK70820.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 ABK70820.1 - 0.15 12.0 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SRP54 PF00448.22 ABK70820.1 - 0.16 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 ABK70820.1 - 0.19 11.6 0.0 7 6.5 0.0 2.4 1 1 1 2 2 2 0 NTPase ResIII PF04851.15 ABK70821.1 - 1.8e-19 70.4 0.0 6.6e-19 68.5 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ABK70821.1 - 3e-13 49.9 0.0 1.7e-12 47.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ABK70821.1 - 7.1e-09 36.0 0.0 1.5e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SWI2_SNF2 PF18766.1 ABK70821.1 - 1.7e-05 24.6 0.0 2.9e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_19 PF13245.6 ABK70821.1 - 9.3e-05 22.8 0.0 0.00019 21.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ABK70821.1 - 0.0026 18.2 1.8 0.0093 16.4 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_11 PF13086.6 ABK70821.1 - 0.0035 17.2 0.0 3.3 7.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 ABK70821.1 - 0.0039 16.9 0.1 0.019 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 ABK70821.1 - 0.063 13.7 0.1 2.3 8.6 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PALP PF00291.25 ABK70821.1 - 0.097 12.1 0.3 8.6 5.7 0.0 2.5 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme AAA_34 PF13872.6 ABK70821.1 - 0.1 11.5 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 UvrD-helicase PF00580.21 ABK70821.1 - 0.11 12.0 0.2 5.3 6.5 0.0 2.2 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain TetR_N PF00440.23 ABK70822.1 - 3e-13 49.3 0.0 5.1e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_24 PF13412.6 ABK70822.1 - 0.0019 17.7 0.0 0.014 15.0 0.0 2.4 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding TetR_C_14 PF17754.1 ABK70822.1 - 0.0063 16.4 0.7 0.018 15.0 0.2 2.1 2 0 0 2 2 2 1 MftR C-terminal domain HTH_Tnp_1_2 PF13022.6 ABK70822.1 - 0.0065 16.6 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix of insertion element transposase HTH_7 PF02796.15 ABK70822.1 - 0.007 16.4 0.0 0.4 10.8 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase MarR PF01047.22 ABK70822.1 - 0.028 14.4 0.1 0.068 13.1 0.1 1.6 1 0 0 1 1 1 0 MarR family DprA_WH PF17782.1 ABK70822.1 - 0.032 14.3 0.6 0.2 11.8 0.0 2.3 2 0 0 2 2 2 0 DprA winged helix domain HTH_IclR PF09339.10 ABK70822.1 - 0.034 13.9 0.0 0.086 12.7 0.0 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_36 PF13730.6 ABK70822.1 - 0.051 13.5 0.0 0.098 12.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain LacI PF00356.21 ABK70822.1 - 0.065 13.0 0.3 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family TnsD PF15978.5 ABK70822.1 - 0.21 10.5 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D adh_short PF00106.25 ABK70823.1 - 9.2e-50 168.8 0.0 1.1e-49 168.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK70823.1 - 4.7e-36 124.5 0.2 5.5e-36 124.3 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK70823.1 - 6.1e-09 36.0 0.1 9.4e-09 35.4 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 ABK70823.1 - 1.7e-05 24.4 0.0 2.2e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) T7SS_ESX_EspC PF10824.8 ABK70824.1 - 3.2e-23 82.1 1.7 4.4e-23 81.7 1.7 1.2 1 0 0 1 1 1 1 Excreted virulence factor EspC, type VII ESX diderm WXG100 PF06013.12 ABK70824.1 - 3e-07 30.6 0.1 3.6e-07 30.3 0.1 1.1 1 0 0 1 1 1 1 Proteins of 100 residues with WXG Oxidored_FMN PF00724.20 ABK70826.1 - 9e-61 206.0 0.0 1e-60 205.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 ABK70826.1 - 3.8e-05 22.9 0.1 0.00084 18.5 0.0 2.1 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) G3P_antiterm PF04309.12 ABK70826.1 - 0.0086 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Glycerol-3-phosphate responsive antiterminator His_biosynth PF00977.21 ABK70826.1 - 0.067 12.6 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein DUF2083 PF09856.9 ABK70827.1 - 1.4e-69 233.0 0.0 2.5e-69 232.1 0.0 1.4 1 0 0 1 1 1 1 Predicted transcriptional regulator (DUF2083) Peptidase_M78 PF06114.13 ABK70827.1 - 6.7e-26 90.6 1.0 9.4e-25 86.9 0.1 2.2 2 0 0 2 2 2 1 IrrE N-terminal-like domain HTH_19 PF12844.7 ABK70827.1 - 1e-13 51.1 0.0 9.3e-13 48.0 0.0 2.4 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_3 PF01381.22 ABK70827.1 - 4.2e-12 45.9 0.0 1.3e-11 44.4 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix HTH_31 PF13560.6 ABK70827.1 - 1.2e-10 41.5 0.0 5e-10 39.6 0.0 2.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 ABK70827.1 - 0.00075 19.3 0.1 0.0016 18.2 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 ABK70827.1 - 0.01 16.2 0.0 0.029 14.8 0.0 1.8 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_37 PF13744.6 ABK70827.1 - 0.014 15.3 0.1 0.049 13.6 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 ABK70827.1 - 0.032 13.7 0.1 0.18 11.4 0.1 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_23 PF13384.6 ABK70827.1 - 0.052 13.4 0.2 1.6 8.6 0.0 3.1 3 0 0 3 3 3 0 Homeodomain-like domain Zn_peptidase_2 PF04298.12 ABK70827.1 - 0.054 12.9 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase adh_short_C2 PF13561.6 ABK70828.1 - 1.2e-46 159.1 0.0 1.5e-46 158.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK70828.1 - 2.4e-35 121.8 0.0 2.8e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK70828.1 - 0.00013 21.9 0.1 0.00022 21.2 0.1 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 ABK70828.1 - 0.016 15.5 0.1 0.028 14.7 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain THF_DHG_CYH_C PF02882.19 ABK70828.1 - 0.025 13.9 0.2 0.064 12.6 0.1 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NLPC_P60 PF00877.19 ABK70830.1 - 4.1e-23 81.4 0.0 9.7e-23 80.2 0.0 1.5 2 0 0 2 2 2 1 NlpC/P60 family Abhydrolase_3 PF07859.13 ABK70831.1 - 1.6e-77 260.2 0.2 2e-77 259.8 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ABK70831.1 - 0.0001 21.4 1.1 0.00027 20.0 1.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 ABK70831.1 - 0.00015 20.8 0.0 0.00019 20.4 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 ABK70831.1 - 0.0014 18.2 0.0 0.0044 16.5 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 ABK70831.1 - 0.0083 15.6 3.9 0.08 12.4 1.6 2.8 2 1 0 2 2 2 1 Esterase PHB depolymerase LytR_C PF13399.6 ABK70832.1 - 3.6e-11 43.9 0.1 6.6e-11 43.1 0.1 1.4 1 0 0 1 1 1 1 LytR cell envelope-related transcriptional attenuator DUF3357 PF11837.8 ABK70832.1 - 0.031 14.7 0.0 0.067 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Stm1_N PF09598.10 ABK70832.1 - 0.84 10.5 5.5 0.13 13.1 1.6 1.6 2 0 0 2 2 2 0 Stm1 PucR PF07905.11 ABK70833.1 - 1.5e-19 70.4 0.1 6e-19 68.5 0.0 2.0 2 0 0 2 2 2 1 Purine catabolism regulatory protein-like family HTH_30 PF13556.6 ABK70833.1 - 3.2e-15 55.7 0.1 6.8e-15 54.6 0.1 1.6 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain Sigma70_r4_2 PF08281.12 ABK70833.1 - 0.029 14.0 0.0 0.41 10.4 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_1 PF00126.27 ABK70833.1 - 0.055 13.4 0.8 0.13 12.2 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family Sigma70_r4_2 PF08281.12 ABK70834.1 - 2.7e-05 23.8 0.1 7.4e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.6 ABK70834.1 - 6.2e-05 22.7 0.3 0.0015 18.2 0.0 2.8 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4 PF04545.16 ABK70834.1 - 0.00016 21.1 0.0 0.00031 20.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_28 PF13518.6 ABK70834.1 - 0.00079 19.5 0.5 0.0095 16.0 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain DUF134 PF02001.16 ABK70834.1 - 0.0028 18.2 0.4 0.099 13.2 0.1 2.5 1 1 1 2 2 2 1 Protein of unknown function DUF134 Sigma70_r2 PF04542.14 ABK70834.1 - 0.0048 16.6 1.2 0.011 15.5 0.2 2.1 2 1 0 2 2 2 1 Sigma-70 region 2 HTH_17 PF12728.7 ABK70834.1 - 0.01 16.0 0.6 2.1 8.6 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_10 PF04967.12 ABK70834.1 - 0.024 14.4 0.0 0.29 10.9 0.0 2.3 2 0 0 2 2 2 0 HTH DNA binding domain MLTR_LBD PF17765.1 ABK70835.1 - 7.1e-32 110.8 1.1 1.2e-31 110.1 1.1 1.4 1 0 0 1 1 1 1 MmyB-like transcription regulator ligand binding domain HTH_31 PF13560.6 ABK70835.1 - 1.3e-13 51.1 2.2 1.3e-13 51.1 2.2 2.1 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_3 PF01381.22 ABK70835.1 - 3.9e-10 39.6 0.0 6.5e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 ABK70835.1 - 2.9e-06 27.2 0.0 5e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain DUF5063 PF16702.5 ABK70835.1 - 0.062 13.7 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5063) SpoU_methylase PF00588.19 ABK70836.1 - 1.1e-22 80.7 0.0 1.3e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family FAD_binding_2 PF00890.24 ABK70837.1 - 1.1e-86 291.5 0.0 1.3e-86 291.3 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 ABK70837.1 - 2.2e-06 27.3 0.1 5e-06 26.1 0.2 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 ABK70837.1 - 3.3e-05 23.6 0.5 0.00016 21.4 0.5 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ABK70837.1 - 0.00025 20.4 0.1 0.012 14.9 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ABK70837.1 - 0.00083 18.2 1.0 0.0041 15.9 2.0 1.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 ABK70837.1 - 0.0077 16.4 3.3 0.022 15.0 3.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ABK70837.1 - 0.016 15.7 0.0 4.1 8.0 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ABK70837.1 - 0.21 10.8 5.5 0.15 11.3 2.9 1.9 2 0 0 2 2 2 0 Thi4 family HTH_Tnp_1 PF01527.20 ABK70839.1 - 1.6e-15 57.2 1.1 2.4e-15 56.6 1.1 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 ABK70839.1 - 1.7e-07 30.8 1.2 3.1e-07 30.0 0.1 2.0 2 1 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_1_2 PF13022.6 ABK70839.1 - 4.3e-05 23.7 0.8 0.0035 17.5 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix of insertion element transposase HTH_28 PF13518.6 ABK70839.1 - 0.0001 22.4 0.0 0.00027 21.0 0.0 1.8 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 ABK70839.1 - 0.00018 21.5 0.1 0.00041 20.3 0.1 1.8 1 1 1 2 2 2 1 Winged helix-turn helix Terminase_5 PF06056.12 ABK70839.1 - 0.00033 20.5 0.1 0.00044 20.1 0.1 1.3 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) HTH_17 PF12728.7 ABK70839.1 - 0.00065 19.8 0.1 0.0018 18.4 0.0 1.9 2 1 0 2 2 2 1 Helix-turn-helix domain GerE PF00196.19 ABK70839.1 - 0.00087 18.8 0.0 0.0026 17.2 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family HTH_7 PF02796.15 ABK70839.1 - 0.0013 18.8 0.3 0.0061 16.6 0.0 2.0 2 1 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_11 PF08279.12 ABK70839.1 - 0.0031 17.4 0.1 0.022 14.7 0.0 2.3 2 1 0 2 2 2 1 HTH domain TnsD PF15978.5 ABK70839.1 - 0.01 14.8 0.2 0.011 14.7 0.2 1.0 1 0 0 1 1 1 0 Tn7-like transposition protein D HTH_22 PF13309.6 ABK70839.1 - 0.012 15.7 0.2 0.062 13.4 0.0 2.2 2 2 0 2 2 2 0 HTH domain Sigma70_r4_2 PF08281.12 ABK70839.1 - 0.017 14.8 0.0 0.034 13.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_38 PF13936.6 ABK70839.1 - 0.017 14.8 0.0 0.055 13.2 0.0 1.9 1 1 0 1 1 1 0 Helix-turn-helix domain DUF1804 PF08822.11 ABK70839.1 - 0.025 14.6 0.1 0.033 14.2 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1804) TetR_N PF00440.23 ABK70839.1 - 0.054 13.3 0.0 0.23 11.3 0.0 2.0 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family HTH_3 PF01381.22 ABK70839.1 - 0.083 13.0 2.9 0.11 12.6 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix YdaS_antitoxin PF15943.5 ABK70839.1 - 0.091 12.6 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT F-112 PF09645.10 ABK70839.1 - 0.14 12.3 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 F-112 protein DivIC PF04977.15 ABK70839.1 - 1.3 8.9 5.8 0.56 10.0 3.3 1.7 2 0 0 2 2 2 0 Septum formation initiator MFS_1 PF07690.16 ABK70840.1 - 3.3e-56 190.7 58.0 2e-54 184.9 56.9 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK70840.1 - 3.6e-06 26.1 15.2 3.6e-06 26.1 15.2 3.2 2 2 0 2 2 2 2 Sugar (and other) transporter Tom6 PF17112.5 ABK70840.1 - 0.45 10.1 0.0 0.45 10.1 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom6, fungal MFS_3 PF05977.13 ABK70840.1 - 1.4 7.2 30.4 0.42 8.9 14.7 2.3 2 0 0 2 2 2 0 Transmembrane secretion effector OATP PF03137.20 ABK70840.1 - 5.2 5.2 12.4 2.8 6.1 0.1 3.5 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Dabb PF07876.12 ABK70843.1 - 6.1e-14 52.4 0.0 1.6e-12 47.9 0.0 2.2 2 0 0 2 2 2 1 Stress responsive A/B Barrel Domain Bac_luciferase PF00296.20 ABK70844.1 - 1.4e-39 136.4 4.3 2.2e-39 135.7 3.0 1.8 1 1 1 2 2 2 1 Luciferase-like monooxygenase Ribul_P_3_epim PF00834.19 ABK70845.1 - 1.6e-80 269.2 0.0 1.9e-80 269.0 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 ABK70845.1 - 0.00032 20.5 0.0 0.00045 20.0 0.0 1.4 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain ThiG PF05690.14 ABK70845.1 - 0.0044 16.4 1.1 0.017 14.5 0.5 2.1 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG OMPdecase PF00215.24 ABK70845.1 - 0.0047 16.6 0.1 0.01 15.5 0.1 1.6 2 0 0 2 2 2 1 Orotidine 5'-phosphate decarboxylase / HUMPS family TMP-TENI PF02581.17 ABK70845.1 - 0.05 12.9 0.6 0.55 9.5 0.6 2.1 1 1 0 1 1 1 0 Thiamine monophosphate synthase YmdB PF13277.6 ABK70845.1 - 0.13 11.6 0.0 1.8 7.8 0.0 2.1 2 0 0 2 2 2 0 YmdB-like protein IGPS PF00218.21 ABK70845.1 - 0.17 11.0 0.3 0.28 10.3 0.0 1.5 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase Staphylcoagulse PF04022.12 ABK70845.1 - 0.18 11.4 0.7 0.31 10.6 0.7 1.3 1 0 0 1 1 1 0 Staphylocoagulase repeat HisG PF01634.18 ABK70846.1 - 5e-39 133.8 0.0 6.5e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 ABK70846.1 - 1.6e-23 82.6 0.0 3e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain NmrA PF05368.13 ABK70847.1 - 1.9e-26 93.1 0.0 2.6e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ABK70847.1 - 1.5e-18 67.3 3.6 5.6e-18 65.5 2.3 2.3 2 1 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 ABK70847.1 - 5.2e-06 26.1 0.7 0.00011 21.7 0.2 2.5 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ABK70847.1 - 0.0027 16.8 0.4 0.0075 15.3 0.4 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF485 PF04341.12 ABK70848.1 - 1.2e-36 124.6 1.1 1.4e-36 124.3 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF485 Cellulose_synt PF03552.14 ABK70848.1 - 0.11 11.0 0.1 0.12 10.8 0.1 1.0 1 0 0 1 1 1 0 Cellulose synthase LysR_substrate PF03466.20 ABK70849.1 - 1.6e-34 119.2 9.3 1.6e-34 119.2 9.3 1.4 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 ABK70849.1 - 4.5e-24 84.2 0.3 1e-23 83.0 0.3 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MLTR_LBD PF17765.1 ABK70850.1 - 6.5e-43 146.8 4.8 6.5e-43 146.8 4.8 2.0 2 0 0 2 2 2 1 MmyB-like transcription regulator ligand binding domain HTH_31 PF13560.6 ABK70850.1 - 5.7e-16 58.6 13.1 6.7e-16 58.4 11.3 2.1 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 ABK70850.1 - 4.6e-09 36.2 0.3 9.7e-09 35.2 0.3 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_25 PF13413.6 ABK70850.1 - 0.0013 18.5 0.5 0.0037 17.1 0.5 1.8 1 1 0 1 1 1 1 Helix-turn-helix domain PRODH PF18327.1 ABK70850.1 - 0.054 13.7 0.4 0.054 13.7 0.4 2.8 3 0 0 3 3 3 0 Proline utilization A proline dehydrogenase N-terminal domain HTH_26 PF13443.6 ABK70850.1 - 0.091 13.2 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_19 PF12844.7 ABK70850.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain MLTR_LBD PF17765.1 ABK70851.1 - 3e-36 125.1 5.5 3.8e-36 124.7 5.5 1.2 1 0 0 1 1 1 1 MmyB-like transcription regulator ligand binding domain HTH_31 PF13560.6 ABK70851.1 - 4.4e-13 49.4 6.1 5.8e-13 49.0 4.4 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 ABK70851.1 - 1e-07 31.9 0.0 2.5e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix TetR_N PF00440.23 ABK70852.1 - 1.5e-16 59.9 0.4 3.5e-16 58.7 0.4 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 ABK70852.1 - 1.3e-15 57.7 1.9 6.1e-15 55.5 1.9 2.1 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_5 PF08360.11 ABK70852.1 - 0.037 14.2 0.0 0.063 13.5 0.0 1.5 1 0 0 1 1 1 0 QacR-like protein, C-terminal region TetR_C_7 PF14246.6 ABK70852.1 - 0.04 13.9 0.3 0.12 12.4 0.1 1.9 2 0 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal domain Tugs PF17840.1 ABK70852.1 - 0.16 12.2 0.9 4.1 7.7 0.1 2.9 3 0 0 3 3 3 0 Tethering Ubl4a to BAGS domain Peptidase_M20 PF01546.28 ABK70853.1 - 4.9e-21 75.4 0.6 6.3e-21 75.0 0.6 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ABK70853.1 - 1.6e-14 53.7 0.0 6.1e-14 51.9 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 ABK70853.1 - 3.5e-06 26.8 0.0 0.00044 20.0 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M28 DUF3040 PF11239.8 ABK70853.1 - 0.007 16.6 0.1 0.061 13.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3040) Cyclase PF04199.13 ABK70853.1 - 0.01 16.1 0.0 0.033 14.4 0.0 1.8 1 1 0 1 1 1 0 Putative cyclase AlkA_N PF06029.11 ABK70853.1 - 0.073 13.4 0.3 0.81 10.0 0.0 2.5 2 0 0 2 2 2 0 AlkA N-terminal domain DDE_Tnp_ISL3 PF01610.17 ABK70854.1 - 1.6e-64 217.9 0.0 2.1e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Transposase zf-ISL3 PF14690.6 ABK70854.1 - 1.1e-09 38.8 4.6 1.8e-09 38.1 2.5 2.5 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HTH_Tnp_ISL3 PF13542.6 ABK70854.1 - 2.4e-08 33.2 1.6 7e-08 31.8 1.6 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 adh_short_C2 PF13561.6 ABK70855.1 - 5.8e-52 176.6 1.4 9.1e-51 172.7 1.4 2.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK70855.1 - 3.1e-47 160.6 0.8 2e-46 157.9 0.8 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK70855.1 - 2e-10 40.9 0.3 2.8e-10 40.4 0.3 1.1 1 0 0 1 1 1 1 KR domain Gln_amidase PF15644.6 ABK70855.1 - 0.12 13.4 0.4 33 5.6 0.0 2.6 3 0 0 3 3 3 0 Papain fold toxin 1, glutamine deamidase Abhydrolase_1 PF00561.20 ABK70856.1 - 6.1e-27 94.9 0.0 7.8e-26 91.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ABK70856.1 - 8.9e-22 77.5 0.1 4.4e-18 65.4 0.1 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ABK70856.1 - 2.7e-20 74.0 7.5 3.3e-20 73.6 7.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 ABK70856.1 - 8.5e-05 22.5 0.0 0.47 10.3 0.0 2.6 3 0 0 3 3 3 2 Serine hydrolase Abhydrolase_5 PF12695.7 ABK70856.1 - 0.00014 21.6 0.0 0.093 12.5 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Esterase PF00756.20 ABK70856.1 - 0.0046 16.6 0.0 0.005 16.5 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 ABK70856.1 - 0.024 13.6 0.0 0.048 12.6 0.0 1.5 1 0 0 1 1 1 0 Chlorophyllase enzyme Peptidase_S9 PF00326.21 ABK70856.1 - 0.095 12.2 0.1 2.5 7.5 0.1 2.3 2 1 0 2 2 2 0 Prolyl oligopeptidase family PGAP1 PF07819.13 ABK70856.1 - 0.3 10.8 0.4 5.2 6.7 0.3 2.2 1 1 1 2 2 2 0 PGAP1-like protein PAF-AH_p_II PF03403.13 ABK70856.1 - 0.32 9.5 0.4 1.3 7.5 0.0 1.8 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Bac_luciferase PF00296.20 ABK70857.1 - 1.5e-37 129.7 0.1 1.8e-37 129.4 0.1 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Bac_globin PF01152.21 ABK70858.1 - 1.1e-30 106.3 0.0 1.2e-30 106.1 0.0 1.0 1 0 0 1 1 1 1 Bacterial-like globin Protoglobin PF11563.8 ABK70858.1 - 0.00084 19.3 0.0 0.00099 19.0 0.0 1.3 1 1 0 1 1 1 1 Protoglobin ECH_1 PF00378.20 ABK70859.1 - 5.6e-48 163.4 0.0 6.7e-48 163.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK70859.1 - 1.5e-23 83.8 0.1 1.8e-23 83.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase SnoaL_4 PF13577.6 ABK70860.1 - 3.1e-13 49.9 3.8 4.5e-13 49.4 3.8 1.1 1 0 0 1 1 1 1 SnoaL-like domain Scytalone_dh PF02982.14 ABK70860.1 - 0.094 12.5 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Scytalone dehydratase NfeD PF01957.18 ABK70860.1 - 0.19 12.1 1.4 8.9 6.8 0.9 2.8 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding DUF4440 PF14534.6 ABK70860.1 - 0.31 11.4 3.2 0.62 10.5 3.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) LysM PF01476.20 ABK70862.1 - 2.6e-16 59.4 0.1 1.1e-15 57.4 0.0 1.9 2 0 0 2 2 2 1 LysM domain B_lectin PF01453.24 ABK70862.1 - 3.6e-08 33.9 0.1 0.00053 20.5 0.0 2.2 1 1 1 2 2 2 2 D-mannose binding lectin Phage_tail_X PF05489.12 ABK70862.1 - 0.027 14.1 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Phage Tail Protein X AnfO_nitrog PF09582.10 ABK70862.1 - 0.12 11.7 0.0 20 4.5 0.0 2.8 1 1 2 3 3 3 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) F420H2_quin_red PF04075.14 ABK70863.1 - 1.5e-13 51.0 0.1 1.9e-13 50.6 0.1 1.1 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase DUF2255 PF10012.9 ABK70863.1 - 0.063 13.4 0.1 0.12 12.6 0.1 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) US10 PF17617.2 ABK70864.1 - 0.1 12.7 0.1 0.1 12.6 0.1 1.1 1 0 0 1 1 1 0 Viral unique short region 10 DAO PF01266.24 ABK70865.1 - 3.9e-61 207.6 8.3 4.4e-61 207.4 8.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ABK70865.1 - 1.1e-07 31.4 3.4 0.002 17.4 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ABK70865.1 - 2.1e-07 30.4 4.5 0.0073 15.4 2.5 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 ABK70865.1 - 5.2e-07 29.1 14.2 2.1e-06 27.1 14.2 1.8 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 ABK70865.1 - 1.1e-05 24.5 4.8 0.019 13.8 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_9 PF13454.6 ABK70865.1 - 1.5e-05 25.0 4.1 0.048 13.6 0.3 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 ABK70865.1 - 5.5e-05 23.3 3.3 0.00017 21.7 2.1 2.3 1 1 1 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ABK70865.1 - 8.1e-05 21.5 1.5 0.033 12.9 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 ABK70865.1 - 0.0004 19.9 13.4 0.013 14.8 13.4 2.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase GMC_oxred_N PF00732.19 ABK70865.1 - 0.00044 19.7 0.3 0.059 12.7 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase Pyr_redox PF00070.27 ABK70865.1 - 0.00074 20.0 0.6 0.39 11.3 0.8 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ABK70865.1 - 0.00081 18.8 0.4 0.016 14.6 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 ABK70865.1 - 0.0012 18.2 1.3 0.068 12.4 0.2 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ABK70865.1 - 0.002 17.4 6.1 0.0028 17.0 3.3 2.4 2 1 1 3 3 3 1 FAD binding domain Thi4 PF01946.17 ABK70865.1 - 0.019 14.2 3.9 0.033 13.4 2.1 2.0 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.20 ABK70865.1 - 0.033 14.2 0.2 0.087 12.9 0.2 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NMT1 PF09084.11 ABK70866.1 - 3.8e-09 36.8 0.0 5.5e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.20 ABK70866.1 - 1.2e-06 28.2 0.0 7.7e-06 25.5 0.0 2.2 1 1 1 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_2 PF13379.6 ABK70866.1 - 1.1e-05 25.2 0.1 0.00012 21.9 0.1 2.3 1 1 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 ABK70866.1 - 0.00016 21.3 0.4 0.0004 20.1 0.4 1.8 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein PNTB PF02233.16 ABK70867.1 - 6.7e-196 651.7 16.6 7.6e-196 651.5 16.6 1.0 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit DUF58 PF01882.18 ABK70868.1 - 3.6e-19 68.8 1.0 1.4e-18 67.0 0.7 2.2 2 0 0 2 2 2 1 Protein of unknown function DUF58 Toprim_3 PF13362.6 ABK70868.1 - 4.8 7.6 5.8 45 4.5 0.1 2.9 2 2 0 2 2 2 0 Toprim domain Zincin_2 PF10103.9 ABK70869.1 - 1e-115 386.5 6.0 1.3e-115 386.3 6.0 1.0 1 0 0 1 1 1 1 Zincin-like metallopeptidase Carboxyl_trans PF01039.22 ABK70870.1 - 1.5e-125 419.7 0.0 1.9e-125 419.4 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain ECH_1 PF00378.20 ABK70870.1 - 0.0012 18.2 0.0 0.0031 16.9 0.0 1.6 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ACCA PF03255.14 ABK70870.1 - 0.1 12.5 0.1 1.4 8.7 0.1 2.5 2 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit p450 PF00067.22 ABK70871.1 - 6.8e-24 84.4 0.3 1.7e-09 37.0 0.6 3.6 3 1 0 3 3 3 3 Cytochrome P450 Peptidase_C33 PF05412.12 ABK70871.1 - 0.2 11.7 0.0 0.42 10.7 0.0 1.5 1 0 0 1 1 1 0 Equine arterivirus Nsp2-type cysteine proteinase 4HBT_3 PF13622.6 ABK70872.1 - 1.3e-47 163.1 0.3 1.6e-47 162.8 0.3 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 ABK70872.1 - 1.9e-27 95.7 0.0 3.8e-20 72.1 0.0 3.0 2 1 0 2 2 2 2 Acyl-CoA thioesterase LPD28 PF18843.1 ABK70872.1 - 0.0049 16.5 0.0 0.36 10.5 0.0 2.3 2 0 0 2 2 2 2 Large polyvalent protein associated domain 28 Glyco_hydro_3 PF00933.21 ABK70873.1 - 5.3e-77 259.3 0.0 6.4e-77 259.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain BPD_transp_1 PF00528.22 ABK70874.1 - 8.2e-40 136.5 10.5 8.2e-40 136.5 10.5 1.5 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Cytidylate_kin PF02224.18 ABK70875.1 - 1.9e-75 253.2 2.5 2.2e-75 253.0 2.5 1.0 1 0 0 1 1 1 1 Cytidylate kinase AAA_18 PF13238.6 ABK70875.1 - 3.5e-07 30.8 0.0 2.3e-06 28.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 ABK70875.1 - 7.3e-07 29.5 1.8 1.3e-05 25.4 1.8 2.1 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_33 PF13671.6 ABK70875.1 - 0.00087 19.5 0.7 0.0039 17.3 0.7 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ABK70875.1 - 0.0045 16.7 1.7 0.0045 16.7 1.7 2.3 2 1 0 2 2 2 1 AAA domain SKI PF01202.22 ABK70875.1 - 0.012 15.7 0.8 0.13 12.4 0.1 2.2 2 1 0 2 2 2 0 Shikimate kinase AAA_16 PF13191.6 ABK70875.1 - 0.018 15.4 3.0 0.065 13.6 3.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 ABK70875.1 - 0.043 13.7 0.1 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_6 PF12774.7 ABK70875.1 - 0.044 12.7 0.1 0.096 11.6 0.1 1.5 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region TsaE PF02367.17 ABK70875.1 - 0.089 12.8 0.0 0.39 10.7 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 ABK70875.1 - 0.09 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ABK70875.1 - 0.11 12.8 0.1 0.26 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 ABK70875.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 ABK70875.1 - 0.16 12.4 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Metallophos_2 PF12850.7 ABK70876.1 - 1.4e-26 93.7 0.0 1.6e-26 93.5 0.0 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 ABK70876.1 - 7.1e-06 26.7 0.1 0.00075 20.1 0.0 2.1 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase MFS_1 PF07690.16 ABK70878.1 - 8.9e-21 74.2 41.9 8.9e-21 74.2 41.9 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily PsaL PF02605.15 ABK70878.1 - 2.8 7.6 8.8 0.058 13.0 0.8 2.3 2 2 0 2 2 2 0 Photosystem I reaction centre subunit XI Sugar_tr PF00083.24 ABK70879.1 - 9.9e-38 130.2 28.1 2.3e-35 122.4 28.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ABK70879.1 - 2.2e-27 95.9 48.4 1.5e-16 60.3 22.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ABK70879.1 - 9.4e-06 24.4 20.6 9.4e-06 24.4 20.6 2.4 1 1 1 2 2 2 2 MFS/sugar transport protein zf-CGNR PF11706.8 ABK70880.1 - 1.7e-17 63.0 9.2 2.6e-17 62.4 9.2 1.3 1 0 0 1 1 1 1 CGNR zinc finger ABATE PF07336.11 ABK70880.1 - 4.1e-13 50.1 10.2 6e-13 49.6 10.2 1.3 1 0 0 1 1 1 1 Putative stress-induced transcription regulator ECH_1 PF00378.20 ABK70881.1 - 8.6e-51 172.7 0.0 9.8e-51 172.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK70881.1 - 6.2e-27 95.0 0.5 2e-26 93.3 0.5 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 ABK70881.1 - 0.01 15.8 0.3 0.045 13.7 0.1 1.9 2 0 0 2 2 2 0 Peptidase family S49 CLP_protease PF00574.23 ABK70881.1 - 0.064 13.1 1.8 1.3 8.9 1.2 2.3 1 1 1 2 2 2 0 Clp protease DUF1416 PF07210.12 ABK70882.1 - 4.6e-38 129.0 1.2 5e-38 128.9 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1416) CarboxypepD_reg PF13620.6 ABK70882.1 - 2.3e-09 37.4 4.8 8.9e-09 35.5 4.6 1.8 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 ABK70882.1 - 0.013 15.7 0.1 0.016 15.4 0.1 1.2 1 0 0 1 1 1 0 SdrD B-like domain Big_3_5 PF16640.5 ABK70882.1 - 0.27 11.4 4.9 0.85 9.8 4.9 1.8 1 1 0 1 1 1 0 Bacterial Ig-like domain (group 3) MlaD PF02470.20 ABK70883.1 - 3.8e-12 46.3 0.0 7.1e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 MlaD protein Mce4_CUP1 PF11887.8 ABK70883.1 - 1.7e-07 31.0 2.5 2.1e-07 30.7 1.7 1.4 1 1 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative DUF948 PF06103.11 ABK70883.1 - 0.00028 21.1 0.4 0.0066 16.7 0.2 2.5 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF948) DUF4404 PF14357.6 ABK70883.1 - 0.0005 20.7 0.4 0.0083 16.7 0.0 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF4404) Baculo_PEP_C PF04513.12 ABK70883.1 - 0.00064 19.8 1.8 0.013 15.5 1.8 2.3 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus EzrA PF06160.12 ABK70883.1 - 0.13 10.4 0.0 0.18 10.0 0.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Lactamase_B PF00753.27 ABK70884.1 - 1.9e-30 106.3 1.1 2.5e-30 106.0 1.1 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ABK70884.1 - 0.00026 20.6 0.8 0.00059 19.4 0.8 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ABK70884.1 - 0.0042 17.0 0.1 0.0071 16.2 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF2905 PF11146.8 ABK70885.1 - 0.017 15.3 2.1 0.017 15.3 2.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2905) DUF3185 PF11381.8 ABK70885.1 - 0.046 13.7 3.4 0.049 13.6 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) DUF3040 PF11239.8 ABK70885.1 - 1.8 8.9 5.3 1.9 8.8 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Peptidase_M28 PF04389.17 ABK70886.1 - 1.1e-39 136.1 0.0 1.6e-39 135.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ABK70886.1 - 6.3e-06 26.1 0.3 1.7e-05 24.7 0.3 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 ABK70886.1 - 0.00016 21.4 0.0 0.00034 20.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 SSB PF00436.25 ABK70887.1 - 2.3e-17 62.9 0.0 3e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Pyr_redox_3 PF13738.6 ABK70888.1 - 4.6e-13 49.1 0.0 1.9e-12 47.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ABK70888.1 - 1.3e-12 46.9 0.0 6.6e-12 44.6 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ABK70888.1 - 1.2e-08 35.0 0.1 4.4e-08 33.2 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 ABK70888.1 - 6.2e-08 32.2 0.1 0.00071 18.8 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 ABK70888.1 - 2.4e-07 30.7 4.7 9.2e-05 22.2 1.0 2.8 1 1 2 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ABK70888.1 - 2.1e-05 23.9 0.0 0.00033 20.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ABK70888.1 - 0.002 17.4 0.0 0.0047 16.2 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 ABK70888.1 - 0.0038 16.3 0.0 0.024 13.7 0.1 2.3 2 1 0 2 2 2 1 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 ABK70888.1 - 0.0045 16.4 0.0 0.022 14.1 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 ABK70888.1 - 0.0073 16.4 0.0 4.8 7.3 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 ABK70888.1 - 0.0085 15.2 0.2 0.017 14.2 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 ABK70888.1 - 0.019 14.2 0.1 0.44 9.8 0.0 2.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 ABK70888.1 - 0.021 14.8 1.0 0.66 10.0 1.2 3.2 3 1 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 ABK70888.1 - 0.16 12.5 0.1 0.49 11.0 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase T7SS_ESX_EspC PF10824.8 ABK70889.1 - 0.047 14.2 0.2 0.047 14.2 0.2 2.3 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm zf-UBP PF02148.19 ABK70890.1 - 1.9e-13 50.6 3.0 2.3e-13 50.3 3.0 1.1 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein CbiX PF01903.17 ABK70891.1 - 1.4e-31 109.0 0.4 4.1e-15 56.0 0.1 2.1 2 0 0 2 2 2 2 CbiX CbiK PF06180.11 ABK70891.1 - 0.00028 20.3 0.0 0.45 9.8 0.0 2.1 1 1 0 2 2 2 2 Cobalt chelatase (CbiK) Ferrochelatase PF00762.19 ABK70891.1 - 0.15 11.1 0.0 0.4 9.7 0.0 1.7 2 1 1 3 3 3 0 Ferrochelatase MutS_I PF01624.20 ABK70891.1 - 0.2 11.9 0.0 0.31 11.3 0.0 1.3 1 0 0 1 1 1 0 MutS domain I Aldedh PF00171.22 ABK70894.1 - 2.8e-154 514.1 0.0 3.4e-154 513.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 ABK70894.1 - 0.21 10.6 0.0 0.28 10.2 0.0 1.1 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) TauE PF01925.19 ABK70895.1 - 1.5e-38 132.8 31.8 1.7e-38 132.6 31.8 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE NADH-u_ox-rdase PF10785.9 ABK70895.1 - 1.1 10.0 4.1 2.8 8.7 0.1 3.0 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Aminotran_3 PF00202.21 ABK70896.1 - 2.8e-72 243.6 0.0 3.5e-72 243.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Thioredoxin_4 PF13462.6 ABK70897.1 - 1.7e-21 77.1 0.0 2.2e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Dak1 PF02733.17 ABK70898.1 - 1.5e-105 352.5 0.2 2.2e-105 352.0 0.2 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 ABK70898.1 - 1.4e-43 148.8 9.3 1.4e-43 148.8 9.3 2.1 2 0 0 2 2 2 1 DAK2 domain APH PF01636.23 ABK70899.1 - 1.1e-33 117.1 3.3 1.6e-33 116.7 3.3 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 ABK70899.1 - 3.2e-06 26.7 0.0 4.5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 ABK70899.1 - 0.025 14.2 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.11 ABK70899.1 - 0.04 12.8 0.0 0.058 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Kdo PF06293.14 ABK70899.1 - 0.078 12.3 0.0 16 4.7 0.0 2.9 3 1 1 4 4 4 0 Lipopolysaccharide kinase (Kdo/WaaP) family FANC_SAP PF18081.1 ABK70899.1 - 2.3 8.4 6.1 2.7 8.2 0.0 2.9 3 0 0 3 3 3 0 Fanconi anemia-associated nuclease SAP domain p450 PF00067.22 ABK70900.1 - 1e-33 116.8 0.0 1.9e-27 96.2 0.0 3.1 2 1 0 2 2 2 2 Cytochrome P450 Acetyltransf_5 PF13444.6 ABK70901.1 - 2.3e-20 73.2 0.0 4.2e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ABK70901.1 - 0.015 15.5 0.0 0.023 14.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family FAD_binding_2 PF00890.24 ABK70902.1 - 1.4e-86 291.2 1.4 1.8e-86 290.9 1.4 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 ABK70902.1 - 3.6e-07 29.9 1.7 1e-05 25.1 1.2 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase DAO PF01266.24 ABK70902.1 - 0.0004 20.1 3.4 0.0011 18.7 3.4 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase adh_short_C2 PF13561.6 ABK70903.1 - 2.7e-48 164.6 0.3 3e-48 164.4 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK70903.1 - 1.1e-37 129.4 0.0 1.3e-37 129.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Aldedh PF00171.22 ABK70904.1 - 2.9e-156 520.6 0.1 3.3e-156 520.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OmdA PF13376.6 ABK70904.1 - 0.0044 17.0 0.2 0.0087 16.0 0.2 1.5 1 0 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated LGT PF01790.18 ABK70905.1 - 1.4e-36 126.0 3.6 1.7e-36 125.7 3.6 1.0 1 0 0 1 1 1 1 Prolipoprotein diacylglyceryl transferase DUF456 PF04306.13 ABK70905.1 - 0.015 15.6 5.3 0.015 15.6 5.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF456) TauE PF01925.19 ABK70905.1 - 0.21 11.2 16.2 0.2 11.2 2.1 3.2 2 1 1 3 3 3 0 Sulfite exporter TauE/SafE Gly-zipper_YMGG PF13441.6 ABK70905.1 - 6.7 6.5 14.6 0.082 12.7 1.9 2.5 2 1 0 2 2 2 0 YMGG-like Gly-zipper MNHE PF01899.16 ABK70905.1 - 8.8 6.1 6.9 1 9.1 1.3 2.3 3 0 0 3 3 3 0 Na+/H+ ion antiporter subunit ECH_1 PF00378.20 ABK70906.1 - 8.3e-54 182.5 0.0 9.2e-54 182.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK70906.1 - 1.8e-26 93.5 0.0 2.7e-22 79.7 0.0 2.2 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ATP-cone PF03477.16 ABK70907.1 - 2.2e-14 53.8 0.0 3e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 ATP cone domain TF_Zn_Ribbon PF08271.12 ABK70907.1 - 0.004 16.6 2.3 0.69 9.5 0.1 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding Cys_rich_CPXG PF14255.6 ABK70907.1 - 0.064 13.2 0.8 2 8.4 0.1 2.2 2 0 0 2 2 2 0 Cysteine-rich CPXCG Elf1 PF05129.13 ABK70907.1 - 0.098 12.7 0.3 0.15 12.1 0.3 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-ribbon_3 PF13248.6 ABK70907.1 - 0.14 11.6 1.1 5.1 6.6 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-FPG_IleRS PF06827.14 ABK70907.1 - 0.24 11.3 4.2 5.2 7.0 0.4 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Lar_restr_allev PF14354.6 ABK70907.1 - 0.24 11.8 1.7 0.72 10.3 1.7 1.8 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-C2H2_4 PF13894.6 ABK70907.1 - 0.6 11.1 5.0 0.96 10.5 0.1 3.0 3 1 0 3 3 3 0 C2H2-type zinc finger Ogr_Delta PF04606.12 ABK70907.1 - 3.6 7.7 5.9 27 4.8 5.9 2.3 1 1 0 1 1 1 0 Ogr/Delta-like zinc finger ABM PF03992.16 ABK70908.1 - 5.6e-14 52.0 0.1 7.2e-14 51.7 0.1 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase PASTA PF03793.19 ABK70909.1 - 0.0077 16.1 0.5 0.013 15.3 0.1 1.7 2 0 0 2 2 2 1 PASTA domain Coilin_N PF15862.5 ABK70909.1 - 0.084 12.7 0.4 0.11 12.3 0.4 1.1 1 0 0 1 1 1 0 Coilin N-terminus p450 PF00067.22 ABK70910.1 - 1.2e-61 208.8 0.0 5.9e-51 173.7 0.0 1.9 2 0 0 2 2 2 2 Cytochrome P450 WES_acyltransf PF03007.16 ABK70911.1 - 1.6e-78 264.1 0.5 2.2e-78 263.7 0.1 1.4 2 0 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 ABK70911.1 - 8e-39 132.9 0.0 1.8e-38 131.8 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1298) PPE PF00823.19 ABK70912.1 - 5.1e-62 208.6 23.8 5.1e-62 208.6 23.8 2.1 3 0 0 3 3 3 1 PPE family Nepo_coat_C PF03688.14 ABK70912.1 - 0.13 12.1 0.3 0.21 11.4 0.3 1.3 1 0 0 1 1 1 0 Nepovirus coat protein, C-terminal domain WXG100 PF06013.12 ABK70912.1 - 0.95 9.7 10.7 0.13 12.5 6.2 1.9 2 0 0 2 2 2 0 Proteins of 100 residues with WXG TetR_N PF00440.23 ABK70913.1 - 1.9e-16 59.6 2.2 2.5e-16 59.2 0.7 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_Tnp_1_2 PF13022.6 ABK70913.1 - 0.019 15.1 0.0 0.049 13.8 0.0 1.8 2 1 0 2 2 2 0 Helix-turn-helix of insertion element transposase HTH_24 PF13412.6 ABK70913.1 - 0.099 12.2 0.0 13 5.5 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding PknH_C PF14032.6 ABK70914.1 - 6.1e-37 127.3 0.1 9.4e-37 126.7 0.1 1.3 1 0 0 1 1 1 1 PknH-like extracellular domain RskA PF10099.9 ABK70914.1 - 0.017 15.5 1.9 0.024 14.9 1.9 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA STAS_2 PF13466.6 ABK70914.1 - 0.053 13.9 3.3 0.2 12.0 1.0 2.4 2 0 0 2 2 2 0 STAS domain LCM PF04072.14 ABK70915.1 - 7.1e-69 231.5 0.5 1e-68 231.0 0.5 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase DUF4701 PF15773.5 ABK70915.1 - 0.027 13.5 0.0 0.039 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4701) DUF308 PF03729.13 ABK70916.1 - 0.0012 19.1 9.0 0.0014 18.9 9.0 1.1 1 0 0 1 1 1 1 Short repeat of unknown function (DUF308) DUF2905 PF11146.8 ABK70916.1 - 0.058 13.6 16.0 0.46 10.7 4.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2905) Tetraspanin PF00335.20 ABK70916.1 - 0.13 11.9 5.8 0.16 11.7 5.8 1.1 1 0 0 1 1 1 0 Tetraspanin family TMEM100 PF16311.5 ABK70916.1 - 0.14 11.7 5.4 0.15 11.7 5.4 1.0 1 0 0 1 1 1 0 Transmembrane protein 100 DUF202 PF02656.15 ABK70916.1 - 0.23 11.9 7.3 0.32 11.5 7.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF2892 PF11127.8 ABK70916.1 - 0.67 10.0 9.6 0.9 9.6 9.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) DUF3185 PF11381.8 ABK70916.1 - 0.88 9.6 16.3 1.4 9.0 4.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) Sdh_cyt PF01127.22 ABK70916.1 - 0.93 9.5 8.6 0.97 9.5 8.6 1.0 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF373 PF04123.13 ABK70916.1 - 1.6 8.1 10.8 1.7 8.0 10.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Fig1 PF12351.8 ABK70916.1 - 2.2 8.2 7.0 2.6 7.9 7.0 1.1 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 DUF973 PF06157.11 ABK70916.1 - 3.6 6.6 12.1 3.8 6.5 12.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Trp_oprn_chp PF09534.10 ABK70916.1 - 3.7 7.3 5.8 0.61 9.9 2.2 1.5 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2207 PF09972.9 ABK70916.1 - 3.9 6.1 8.1 3.7 6.2 8.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) YtpI PF14007.6 ABK70916.1 - 4.1 7.6 11.6 20 5.4 11.6 1.9 1 1 0 1 1 1 0 YtpI-like protein CrgA PF06781.12 ABK70916.1 - 4.6 7.4 8.6 5.4 7.1 8.6 1.1 1 0 0 1 1 1 0 Cell division protein CrgA Phage_holin_3_6 PF07332.11 ABK70916.1 - 5.5 7.1 16.2 6.1 6.9 16.2 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III TMEM238 PF15125.6 ABK70916.1 - 6.1 7.1 15.4 0.4 10.9 6.4 2.1 1 1 1 2 2 2 0 TMEM238 protein family DUF3040 PF11239.8 ABK70916.1 - 7.9 6.8 16.4 26 5.2 6.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) DUF779 PF05610.11 ABK70917.1 - 8.5e-46 154.1 0.0 1.1e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF779) Ada_Zn_binding PF02805.16 ABK70918.1 - 3e-29 100.8 6.9 5.4e-29 100.0 6.9 1.5 1 0 0 1 1 1 1 Metal binding domain of Ada AlkA_N PF06029.11 ABK70918.1 - 1.5e-28 99.4 0.4 3.5e-28 98.2 0.1 1.8 2 0 0 2 2 2 1 AlkA N-terminal domain HTH_18 PF12833.7 ABK70918.1 - 3.4e-17 62.5 0.8 8.2e-17 61.2 0.8 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 ABK70918.1 - 4.7e-09 36.1 0.0 5.1e-05 23.3 0.0 2.6 3 0 0 3 3 3 2 Bacterial regulatory helix-turn-helix proteins, AraC family HhH-GPD PF00730.25 ABK70918.1 - 1.4e-06 28.7 0.0 7.6e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 ABK70918.1 - 0.00027 20.6 0.1 0.00094 18.9 0.1 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 ABK70918.1 - 0.11 13.1 0.0 7.1 7.3 0.0 2.8 2 0 0 2 2 2 0 Helix-hairpin-helix domain Methyltransf_34 PF11312.8 ABK70918.1 - 0.24 10.6 0.3 0.38 9.9 0.3 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase PNP_UDP_1 PF01048.20 ABK70919.1 - 5e-50 169.9 1.8 5.8e-50 169.7 1.8 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily NUP PF06516.11 ABK70919.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Purine nucleoside permease (NUP) Peptidase_M23 PF01551.22 ABK70920.1 - 2.6e-18 66.0 0.0 5.3e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M23 DALR_1 PF05746.15 ABK70921.1 - 2.1e-42 144.0 0.0 1.6e-41 141.2 0.0 2.1 2 0 0 2 2 2 1 DALR anticodon binding domain tRNA-synt_1d PF00750.19 ABK70921.1 - 4.7e-20 71.8 0.1 1e-18 67.4 0.1 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (R) Arg_tRNA_synt_N PF03485.16 ABK70921.1 - 8.7e-20 71.1 0.0 2.7e-19 69.5 0.0 1.9 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1g PF09334.11 ABK70921.1 - 1.3e-07 30.8 0.4 0.09 11.5 0.0 3.3 2 1 1 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 ABK70921.1 - 1.3e-07 30.2 0.0 2.9e-05 22.5 0.0 2.3 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 ABK70921.1 - 0.0044 16.0 0.0 0.37 9.6 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class I (K) HIRAN PF08797.11 ABK70921.1 - 0.012 15.5 0.0 0.032 14.1 0.0 1.7 1 0 0 1 1 1 0 HIRAN domain HTH_31 PF13560.6 ABK70922.1 - 0.0095 16.3 3.0 0.017 15.4 0.3 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_25 PF13413.6 ABK70922.1 - 0.031 14.1 0.1 0.059 13.2 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_3 PF01381.22 ABK70922.1 - 0.038 14.0 0.1 0.1 12.7 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix HTH_19 PF12844.7 ABK70922.1 - 0.088 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain UVR PF02151.19 ABK70922.1 - 0.24 11.2 1.5 16 5.4 0.1 2.5 2 0 0 2 2 2 0 UvrB/uvrC motif Guanylate_kin PF00625.21 ABK70923.1 - 4.8e-41 140.4 0.0 5.4e-41 140.3 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 ABK70923.1 - 3.7e-07 30.7 0.1 5.1e-07 30.2 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 ABK70923.1 - 1.9e-05 25.2 0.0 6.9e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain CPT PF07931.12 ABK70923.1 - 0.0011 18.9 0.0 0.0027 17.6 0.0 1.6 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 ABK70923.1 - 0.0014 18.8 0.2 0.013 15.6 0.2 2.3 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ABK70923.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 ABK70923.1 - 0.014 15.7 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 ABK70923.1 - 0.037 13.7 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase MMR_HSR1 PF01926.23 ABK70923.1 - 0.038 14.1 0.0 0.045 13.8 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase Rad17 PF03215.15 ABK70923.1 - 0.059 13.3 0.0 0.078 12.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 ABK70923.1 - 0.21 11.4 0.0 0.43 10.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain IclR PF01614.18 ABK70924.1 - 3.1e-33 114.4 0.0 5.1e-33 113.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 ABK70924.1 - 7.2e-10 38.5 1.1 1.5e-09 37.5 1.1 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain Rrf2 PF02082.20 ABK70924.1 - 0.0052 17.1 0.1 0.018 15.4 0.1 1.9 1 0 0 1 1 1 1 Transcriptional regulator HTH_36 PF13730.6 ABK70924.1 - 0.0074 16.2 0.1 0.32 11.0 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_11 PF08279.12 ABK70924.1 - 0.0082 16.1 0.0 0.025 14.5 0.1 1.7 2 0 0 2 2 2 1 HTH domain MarR_2 PF12802.7 ABK70924.1 - 0.0087 15.9 0.2 0.019 14.9 0.2 1.6 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 ABK70924.1 - 0.0087 15.9 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR PF01047.22 ABK70924.1 - 0.013 15.5 0.1 0.04 13.9 0.1 1.9 2 0 0 2 2 2 0 MarR family Sulfolobus_pRN PF05584.11 ABK70924.1 - 0.02 14.9 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 Sulfolobus plasmid regulatory protein HTH_Crp_2 PF13545.6 ABK70924.1 - 0.023 14.7 0.2 0.057 13.4 0.2 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_5 PF01022.20 ABK70924.1 - 0.035 14.0 0.0 0.32 10.9 0.1 2.2 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 ABK70924.1 - 0.047 13.2 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DprA_WH PF17782.1 ABK70924.1 - 0.11 12.7 0.7 0.29 11.3 0.5 1.9 2 0 0 2 2 2 0 DprA winged helix domain ABC_tran PF00005.27 ABK70925.1 - 3e-30 105.5 0.0 4e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK70925.1 - 2.7e-11 43.8 0.1 6.8e-05 22.8 0.1 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK70925.1 - 5.2e-07 29.3 0.1 7.7e-05 22.2 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ABK70925.1 - 1.9e-05 24.3 0.0 3.9e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.9 ABK70925.1 - 5.1e-05 22.3 0.5 0.4 9.4 0.0 3.0 2 1 0 2 2 2 2 Predicted ATPase of the ABC class AAA_23 PF13476.6 ABK70925.1 - 9.2e-05 23.0 0.0 0.00013 22.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ABK70925.1 - 0.0015 18.3 1.8 0.01 15.5 1.8 2.2 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 ABK70925.1 - 0.0026 17.6 0.0 0.011 15.5 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 ABK70925.1 - 0.0032 17.4 0.0 0.0064 16.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase TsaE PF02367.17 ABK70925.1 - 0.0073 16.3 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynamin_N PF00350.23 ABK70925.1 - 0.014 15.5 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 0 Dynamin family MMR_HSR1 PF01926.23 ABK70925.1 - 0.024 14.7 0.1 0.046 13.8 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 ABK70925.1 - 0.031 14.7 0.1 0.047 14.1 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.7 ABK70925.1 - 0.054 12.4 0.0 2.2 7.1 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain AAA_22 PF13401.6 ABK70925.1 - 0.06 13.6 0.1 0.12 12.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_27 PF13514.6 ABK70925.1 - 0.06 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2813 PF11398.8 ABK70925.1 - 0.061 12.6 0.0 0.094 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) MukB PF04310.12 ABK70925.1 - 0.069 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 MukB N-terminal AAA PF00004.29 ABK70925.1 - 0.073 13.5 0.0 0.32 11.4 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 ABK70925.1 - 0.074 12.6 0.1 0.26 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 ABK70925.1 - 0.1 11.7 0.0 0.25 10.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NACHT PF05729.12 ABK70925.1 - 0.1 12.5 0.5 0.22 11.4 0.2 1.6 2 0 0 2 2 2 0 NACHT domain Transp_cyt_pur PF02133.15 ABK70926.1 - 1.9e-89 300.4 40.4 2.3e-89 300.2 40.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Esterase PF00756.20 ABK70927.1 - 2.8e-64 217.2 0.2 2.8e-64 217.2 0.2 1.3 2 0 0 2 2 2 1 Putative esterase DivIVA PF05103.13 ABK70929.1 - 8.2e-11 42.1 0.0 0.00033 20.7 0.0 2.0 2 0 0 2 2 2 2 DivIVA protein GATase PF00117.28 ABK70930.1 - 2.8e-09 37.0 0.0 9.8e-09 35.3 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ABK70930.1 - 2.3e-05 24.3 0.0 0.0003 20.6 0.0 2.0 2 0 0 2 2 2 1 Peptidase C26 Esterase_phd PF10503.9 ABK70931.1 - 1.1e-19 70.8 0.5 2.1e-19 69.9 0.5 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 ABK70931.1 - 0.00016 21.2 0.1 0.00055 19.5 0.0 1.8 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 ABK70931.1 - 0.0033 17.2 0.0 0.01 15.7 0.0 1.6 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 ABK70931.1 - 0.044 13.4 0.1 0.072 12.7 0.1 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 ABK70931.1 - 0.068 12.8 0.0 0.12 12.0 0.0 1.4 1 1 0 1 1 1 0 Putative esterase TetR_N PF00440.23 ABK70932.1 - 1.7e-06 27.7 0.2 3.8e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family Methyltransf_11 PF08241.12 ABK70933.1 - 2.3e-11 44.2 1.3 3.2e-10 40.5 0.1 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABK70933.1 - 1e-09 39.0 1.5 4.1e-09 37.0 0.1 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_8 PF05148.15 ABK70933.1 - 0.00033 20.6 0.0 0.0021 18.0 0.0 2.1 2 1 1 3 3 3 1 Hypothetical methyltransferase Methyltransf_23 PF13489.6 ABK70933.1 - 0.0019 18.0 0.0 0.003 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK70933.1 - 0.0035 18.1 0.2 0.012 16.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 ABK70933.1 - 0.0039 16.8 0.0 0.0074 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 ABK70933.1 - 0.0074 16.1 0.0 0.021 14.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 ABK70933.1 - 0.074 12.8 0.1 0.15 11.8 0.0 1.5 2 0 0 2 2 2 0 Lysine methyltransferase Ubie_methyltran PF01209.18 ABK70933.1 - 0.17 11.2 0.1 0.75 9.1 0.0 2.0 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Acyl-CoA_dh_2 PF08028.11 ABK70934.1 - 7.5e-10 39.2 9.7 1.2e-09 38.6 9.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK70934.1 - 1.3e-08 34.9 0.0 2.4e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DNA_gyraseB_C PF00986.21 ABK70935.1 - 1.5e-14 53.9 0.1 3e-14 53.0 0.1 1.5 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus DNA_gyraseB PF00204.25 ABK70935.1 - 6.4e-11 42.0 0.0 1.1e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.22 ABK70935.1 - 1.4e-10 41.3 0.0 2.7e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.26 ABK70935.1 - 1.4e-09 38.4 0.0 2.9e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 ABK70935.1 - 8.3e-05 22.4 0.5 0.00021 21.2 0.5 1.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PQQ_3 PF13570.6 ABK70936.1 - 1.2e-14 54.2 23.1 0.00054 20.4 0.3 7.0 7 0 0 7 7 7 5 PQQ-like domain PQQ_2 PF13360.6 ABK70936.1 - 6.3e-13 48.9 9.9 4e-09 36.4 3.0 3.4 2 2 1 3 3 3 3 PQQ-like domain PQQ PF01011.21 ABK70936.1 - 8.7e-05 22.3 5.1 0.00062 19.6 0.1 4.3 4 0 0 4 4 4 1 PQQ enzyme repeat DUF1899 PF08953.11 ABK70936.1 - 0.0084 16.0 0.1 0.017 15.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) T2SS-T3SS_pil_N PF13629.6 ABK70936.1 - 0.14 11.9 0.2 0.73 9.6 0.0 2.3 3 0 0 3 3 3 0 Pilus formation protein N terminal region adh_short PF00106.25 ABK70937.1 - 5.5e-42 143.5 0.3 6.8e-42 143.1 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK70937.1 - 6.4e-39 133.9 0.5 7.6e-39 133.6 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ABK70937.1 - 6e-05 22.6 0.3 0.00013 21.6 0.3 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 ABK70937.1 - 8e-05 22.6 4.8 0.001 19.0 4.8 2.3 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 ABK70937.1 - 0.0026 18.0 0.3 0.005 17.1 0.3 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 ABK70937.1 - 0.0027 17.8 0.0 0.0049 16.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 ABK70937.1 - 0.0067 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TrkA_N PF02254.18 ABK70937.1 - 0.04 14.2 0.1 0.072 13.4 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain YbaB_DNA_bd PF02575.16 ABK70938.1 - 6e-32 109.7 2.4 6.7e-32 109.6 2.4 1.0 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family DUF3138 PF11336.8 ABK70938.1 - 0.028 13.0 1.3 0.031 12.9 1.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) NMO PF03060.15 ABK70939.1 - 4e-42 144.8 13.1 1.5e-30 106.8 4.6 2.6 1 1 2 3 3 3 2 Nitronate monooxygenase IMPDH PF00478.25 ABK70939.1 - 8.8e-11 41.4 5.5 8e-05 21.8 3.5 2.3 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 ABK70939.1 - 0.00041 19.5 7.8 0.00041 19.5 7.8 1.9 1 1 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 ABK70939.1 - 0.00087 18.8 0.1 0.0013 18.3 0.1 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein NanE PF04131.14 ABK70939.1 - 0.016 14.4 0.0 0.032 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase TMP-TENI PF02581.17 ABK70939.1 - 0.055 12.8 0.2 0.11 11.9 0.2 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase PEP_hydrolase PF09370.10 ABK70939.1 - 0.084 12.1 1.2 0.18 11.0 0.0 2.0 2 0 0 2 2 2 0 Phosphoenolpyruvate hydrolase-like DUF1028 PF06267.12 ABK70939.1 - 0.22 11.3 6.1 0.04 13.7 2.3 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF1028) SnoaL_2 PF12680.7 ABK70940.1 - 1.9e-10 41.3 2.7 2.3e-10 41.0 2.7 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 ABK70940.1 - 0.00014 22.1 0.5 0.00022 21.4 0.5 1.3 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 ABK70940.1 - 0.0019 18.6 0.7 0.0027 18.1 0.6 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) DSBA PF01323.20 ABK70940.1 - 0.037 13.8 0.0 0.043 13.6 0.0 1.1 1 0 0 1 1 1 0 DSBA-like thioredoxin domain DEAD PF00270.29 ABK70942.1 - 1.6e-14 54.0 0.0 1.9e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 ABK70942.1 - 0.00063 19.8 0.0 0.001 19.1 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 ABK70942.1 - 0.003 17.3 0.1 0.0066 16.2 0.1 1.6 1 1 0 1 1 1 1 AAA domain SNF2_N PF00176.23 ABK70942.1 - 0.23 10.1 0.0 0.28 9.8 0.0 1.1 1 0 0 1 1 1 0 SNF2 family N-terminal domain UDPGT PF00201.18 ABK70943.1 - 1.4e-06 27.5 0.0 2.1e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 ABK70943.1 - 9.2e-05 22.5 0.0 0.00015 21.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 ABK70943.1 - 0.11 11.7 0.0 2.2 7.5 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 1 ABC_tran PF00005.27 ABK70945.1 - 2.9e-58 196.3 0.0 7.5e-30 104.2 0.0 2.2 2 0 0 2 2 2 2 ABC transporter oligo_HPY PF08352.12 ABK70945.1 - 1.8e-25 89.3 0.1 3.7e-16 59.4 0.0 2.4 2 0 0 2 2 2 2 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 ABK70945.1 - 1.2e-13 51.6 2.4 0.00021 21.2 0.0 4.1 2 2 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK70945.1 - 8.1e-08 32.0 0.4 0.0094 15.4 0.0 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ABK70945.1 - 1.3e-07 31.2 0.1 0.011 15.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 ABK70945.1 - 6.1e-07 29.8 0.4 0.014 15.7 0.1 3.1 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ABK70945.1 - 1.5e-06 28.7 1.6 0.014 15.8 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 ABK70945.1 - 1.9e-06 27.9 0.1 0.0082 16.1 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 ABK70945.1 - 4.5e-05 23.6 0.1 0.67 10.1 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 ABK70945.1 - 0.00022 21.0 1.2 0.09 12.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain PRK PF00485.18 ABK70945.1 - 0.00027 20.8 0.0 0.026 14.2 0.0 2.3 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family NACHT PF05729.12 ABK70945.1 - 0.00039 20.4 0.4 0.099 12.6 0.1 2.6 2 1 0 2 2 2 1 NACHT domain AAA PF00004.29 ABK70945.1 - 0.00045 20.7 0.1 0.29 11.6 0.0 3.8 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 ABK70945.1 - 0.00057 19.2 0.2 0.94 8.7 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.17 ABK70945.1 - 0.00088 19.0 0.2 0.015 15.0 0.0 2.6 3 0 0 3 3 3 1 IstB-like ATP binding protein MMR_HSR1 PF01926.23 ABK70945.1 - 0.00088 19.3 0.1 1.2 9.3 0.0 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF87 PF01935.17 ABK70945.1 - 0.0009 19.4 0.4 0.13 12.4 0.0 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_7 PF12775.7 ABK70945.1 - 0.003 17.1 0.0 1.9 8.0 0.0 2.2 2 0 0 2 2 2 2 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 ABK70945.1 - 0.004 16.6 0.1 0.042 13.2 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_5 PF07728.14 ABK70945.1 - 0.004 17.1 0.1 1.6 8.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 ABK70945.1 - 0.0049 17.4 0.0 1.9 9.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AIG1 PF04548.16 ABK70945.1 - 0.0057 16.0 0.4 3 7.1 0.1 2.3 2 0 0 2 2 2 2 AIG1 family AAA_19 PF13245.6 ABK70945.1 - 0.012 16.0 0.1 0.32 11.3 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.6 ABK70945.1 - 0.024 14.3 0.0 2.3 7.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 ABK70945.1 - 0.035 13.5 0.0 1.5 8.2 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Roc PF08477.13 ABK70945.1 - 0.047 13.9 0.0 4.4 7.5 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Sigma54_activat PF00158.26 ABK70945.1 - 0.051 13.3 0.6 16 5.2 0.0 3.2 4 0 0 4 4 4 0 Sigma-54 interaction domain NB-ARC PF00931.22 ABK70945.1 - 0.06 12.5 0.1 2.4 7.3 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain APS_kinase PF01583.20 ABK70945.1 - 0.062 13.2 0.2 3.2 7.6 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase RNA_helicase PF00910.22 ABK70945.1 - 0.063 13.7 0.1 10 6.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase MukB PF04310.12 ABK70945.1 - 0.066 13.0 0.2 0.35 10.6 0.0 2.0 2 0 0 2 2 2 0 MukB N-terminal SbcCD_C PF13558.6 ABK70945.1 - 0.1 12.9 0.3 59 4.0 0.0 3.7 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 ABK70945.1 - 0.1 12.5 0.0 0.54 10.2 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain ATPase PF06745.13 ABK70945.1 - 0.12 11.7 0.1 7.3 5.9 0.0 2.4 2 0 0 2 2 2 0 KaiC ATP-synt_ab PF00006.25 ABK70945.1 - 0.14 11.8 0.0 0.36 10.5 0.0 1.7 2 0 0 2 2 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_13 PF13166.6 ABK70945.1 - 0.15 10.7 0.2 3 6.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 ABK70945.1 - 0.18 11.5 0.0 33 4.0 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain DAP3 PF10236.9 ABK70945.1 - 0.29 10.3 0.1 0.92 8.6 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_25 PF13481.6 ABK70945.1 - 0.41 10.2 10.0 4.9 6.7 4.8 3.4 2 2 0 2 2 2 0 AAA domain ABC_tran PF00005.27 ABK70946.1 - 1.2e-07 32.4 0.0 1.4e-07 32.1 0.0 1.3 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 ABK70946.1 - 0.0019 18.6 0.2 0.0031 17.9 0.2 1.3 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 ABK70946.1 - 0.0052 16.2 0.0 0.013 15.0 0.0 1.5 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 ABK70946.1 - 0.028 14.3 0.0 0.82 9.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 ABK70946.1 - 0.035 14.4 0.1 0.7 10.2 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ABK70946.1 - 0.094 12.3 2.1 0.17 11.5 1.2 2.0 1 1 1 2 2 2 0 AAA domain SecA_DEAD PF07517.14 ABK70947.1 - 1.3e-84 284.0 0.1 1.9e-84 283.4 0.1 1.2 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_PP_bind PF01043.20 ABK70947.1 - 6.6e-21 75.0 0.8 3.5e-20 72.7 0.1 2.3 2 0 0 2 2 2 1 SecA preprotein cross-linking domain SecA_SW PF07516.13 ABK70947.1 - 7.5e-19 68.6 1.1 2.7e-13 50.5 0.0 2.5 1 1 1 2 2 2 2 SecA Wing and Scaffold domain DEAD PF00270.29 ABK70947.1 - 0.0082 15.9 0.1 0.071 12.9 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ABK70947.1 - 0.086 13.2 0.1 0.45 10.9 0.1 2.2 1 1 0 1 1 1 0 Helicase conserved C-terminal domain AMP-binding PF00501.28 ABK70948.1 - 6.9e-68 229.2 0.0 9.1e-68 228.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK70948.1 - 9.7e-18 64.9 2.5 2.3e-17 63.8 2.5 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AI-2E_transport PF01594.16 ABK70949.1 - 8.4e-51 173.1 43.9 1e-50 172.8 43.9 1.0 1 0 0 1 1 1 1 AI-2E family transporter Thump_like PF18096.1 ABK70950.1 - 1.2e-22 79.6 0.5 3.6e-22 78.1 0.2 2.0 2 0 0 2 2 2 1 THUMP domain-like DUF3253 PF11625.8 ABK70950.1 - 0.066 13.5 0.4 0.3 11.4 0.4 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) PaaX PF07848.12 ABK70951.1 - 2.2e-16 59.8 0.5 3.9e-16 59.0 0.5 1.4 1 0 0 1 1 1 1 PaaX-like protein PaaX_C PF08223.11 ABK70951.1 - 7.3e-07 29.4 0.2 1.7e-06 28.2 0.2 1.7 1 1 0 1 1 1 1 PaaX-like protein C-terminal domain DUF5457 PF17540.2 ABK70951.1 - 0.0071 16.4 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5457) LMWPc PF01451.21 ABK70953.1 - 8.6e-20 71.6 0.0 1.1e-19 71.3 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase DUF4091 PF13320.6 ABK70953.1 - 0.036 14.2 0.2 0.062 13.5 0.2 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4091) DUF2604 PF10790.9 ABK70953.1 - 0.07 13.4 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of Unknown function (DUF2604) PEP_mutase PF13714.6 ABK70954.1 - 6.3e-50 169.9 1.9 7.7e-50 169.6 1.9 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 ABK70954.1 - 3.8e-10 38.9 0.1 5e-10 38.5 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family MR_MLE_C PF13378.6 ABK70954.1 - 0.002 17.7 1.9 1.4 8.4 0.2 2.4 2 1 0 2 2 2 2 Enolase C-terminal domain-like Pantoate_transf PF02548.15 ABK70954.1 - 0.027 13.8 0.1 0.43 9.9 0.0 2.3 2 1 0 2 2 2 0 Ketopantoate hydroxymethyltransferase F420H2_quin_red PF04075.14 ABK70956.1 - 3.8e-05 23.8 0.1 4.4e-05 23.6 0.1 1.1 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase WES_acyltransf PF03007.16 ABK70957.1 - 0.0098 15.7 0.6 0.032 14.0 0.5 1.9 2 1 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Zn-ribbon_8 PF09723.10 ABK70958.1 - 3e-09 36.8 0.4 4.4e-09 36.3 0.4 1.3 1 0 0 1 1 1 1 Zinc ribbon domain DUF1178 PF06676.11 ABK70958.1 - 0.04 14.3 0.0 0.045 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) Cyclase PF04199.13 ABK70959.1 - 3.3e-28 98.6 0.2 5e-28 98.0 0.2 1.3 1 0 0 1 1 1 1 Putative cyclase UPF0060 PF02694.15 ABK70960.1 - 2.8e-41 140.1 9.6 3e-41 140.0 9.6 1.0 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family DUF4536 PF15055.6 ABK70960.1 - 0.066 13.5 1.1 0.066 13.5 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) DUF4173 PF13777.6 ABK70960.1 - 0.2 11.1 1.0 1.2 8.5 0.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4173) ArgJ PF01960.18 ABK70960.1 - 0.24 10.1 0.2 0.26 10.0 0.2 1.1 1 0 0 1 1 1 0 ArgJ family DUF4131 PF13567.6 ABK70960.1 - 0.91 9.1 9.3 4.2 7.0 3.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) CHAD PF05235.14 ABK70961.1 - 5.2e-45 154.2 16.9 5.2e-45 154.2 16.9 2.2 3 1 0 3 3 3 1 CHAD domain CYTH PF01928.21 ABK70961.1 - 3e-14 53.4 0.0 6.7e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 CYTH domain DUF4710 PF15828.5 ABK70961.1 - 0.0073 16.4 0.1 0.26 11.5 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4710) SBP_bac_8 PF13416.6 ABK70962.1 - 6.1e-31 108.3 7.3 8.5e-31 107.8 7.3 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 ABK70962.1 - 4e-28 99.3 9.0 4e-28 99.3 9.0 1.5 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 ABK70962.1 - 0.069 12.6 0.0 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein TetR_N PF00440.23 ABK70963.1 - 2.8e-12 46.2 1.0 5.8e-12 45.2 1.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family Glyco_hydro_65m PF03632.15 ABK70965.1 - 3.5e-138 460.7 0.2 4.3e-138 460.4 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.15 ABK70965.1 - 5e-64 216.0 0.0 1e-63 215.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.15 ABK70965.1 - 4.3e-13 49.0 0.3 2.2e-12 46.7 0.0 2.4 3 0 0 3 3 3 1 Glycosyl hydrolase family 65, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK70966.1 - 3.9e-22 78.3 0.0 7.4e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 ABK70966.1 - 1.5e-08 35.0 1.8 0.0027 17.9 0.0 3.2 1 1 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK70966.1 - 2e-07 31.7 0.1 3.5e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 ABK70966.1 - 0.00014 21.6 0.0 0.00027 20.7 0.0 1.4 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal AftA_N PF12250.8 ABK70967.1 - 5.6e-174 578.9 52.3 6.6e-174 578.7 52.3 1.0 1 0 0 1 1 1 1 Arabinofuranosyltransferase N terminal AftA_C PF12249.8 ABK70967.1 - 2.9e-72 242.0 0.1 4.1e-72 241.5 0.1 1.2 1 0 0 1 1 1 1 Arabinofuranosyltransferase A C terminal PlyB_C PF18684.1 ABK70967.1 - 0.086 12.6 0.3 7.4 6.3 0.2 2.3 2 0 0 2 2 2 0 Pleurotolysin B C-terminal domain MlaD PF02470.20 ABK70968.1 - 7.7e-16 58.2 0.1 2.3e-15 56.6 0.1 1.9 1 0 0 1 1 1 1 MlaD protein Mce4_CUP1 PF11887.8 ABK70968.1 - 1.4e-06 28.0 2.6 2.4e-06 27.2 2.6 1.3 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative Prominin PF05478.11 ABK70968.1 - 0.11 10.5 0.2 0.14 10.1 0.2 1.1 1 0 0 1 1 1 0 Prominin Mating_N PF12731.7 ABK70968.1 - 0.15 12.2 0.3 0.43 10.7 0.3 1.8 1 1 0 1 1 1 0 Mating-type protein beta 1 Spc7 PF08317.11 ABK70968.1 - 0.22 10.3 0.1 0.33 9.8 0.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 ABK70968.1 - 0.29 11.2 6.2 1.9 8.5 4.4 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus cobW PF02492.19 ABK70969.1 - 4.1e-57 192.6 0.2 5.2e-57 192.3 0.2 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 ABK70969.1 - 2.3e-22 78.7 0.0 5.9e-22 77.4 0.0 1.7 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 ABK70969.1 - 0.0001 22.2 0.0 0.094 12.6 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MeaB PF03308.16 ABK70969.1 - 0.0012 17.9 0.1 0.088 11.8 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 ABK70969.1 - 0.018 14.6 0.0 3.3 7.2 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain T2SSE PF00437.20 ABK70969.1 - 0.018 14.1 0.0 0.034 13.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 ABK70969.1 - 0.028 14.8 0.3 0.12 12.7 0.3 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 ABK70969.1 - 0.035 14.4 0.0 0.84 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 ABK70969.1 - 0.037 14.0 0.0 0.077 13.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 ABK70969.1 - 0.079 12.9 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MobB PF03205.14 ABK70969.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Glyco_hydro_30C PF17189.4 ABK70969.1 - 0.19 11.9 0.0 0.46 10.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 30 beta sandwich domain Zeta_toxin PF06414.12 ABK70969.1 - 0.22 10.8 0.0 0.45 9.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Xan_ur_permease PF00860.20 ABK70970.1 - 7.1e-70 235.7 46.2 7.1e-70 235.7 46.2 1.9 2 1 0 2 2 2 1 Permease family DeoRC PF00455.22 ABK70972.1 - 4.2e-52 176.3 0.4 5.8e-52 175.9 0.4 1.2 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 ABK70972.1 - 1.1e-16 60.3 0.4 2e-16 59.4 0.4 1.4 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 ABK70972.1 - 1.3e-06 28.3 0.0 2.2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 HTH domain GntR PF00392.21 ABK70972.1 - 4.5e-05 23.0 0.8 0.00012 21.7 0.8 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 ABK70972.1 - 0.0041 17.1 0.6 0.0041 17.1 0.6 2.0 3 0 0 3 3 2 1 Helix-turn-helix domain HTH_12 PF08461.10 ABK70972.1 - 0.0042 17.0 0.0 0.012 15.6 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain Rrf2 PF02082.20 ABK70972.1 - 0.0051 17.1 0.2 0.014 15.7 0.1 1.7 2 0 0 2 2 1 1 Transcriptional regulator HTH_23 PF13384.6 ABK70972.1 - 0.0067 16.2 1.5 0.015 15.1 0.6 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_9 PF08221.11 ABK70972.1 - 0.0079 16.3 0.1 0.027 14.5 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 helix-turn-helix domain FeoC PF09012.10 ABK70972.1 - 0.0088 16.1 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 FeoC like transcriptional regulator TrmB PF01978.19 ABK70972.1 - 0.0095 15.8 0.1 0.018 14.9 0.1 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_AsnC-type PF13404.6 ABK70972.1 - 0.014 15.2 1.4 0.11 12.4 0.4 2.8 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 ABK70972.1 - 0.021 14.3 2.3 0.033 13.6 0.5 2.3 3 0 0 3 3 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_5 PF01022.20 ABK70972.1 - 0.033 14.0 0.0 0.076 12.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_Crp_2 PF13545.6 ABK70972.1 - 0.034 14.1 0.1 0.087 12.8 0.1 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Sigma70_r4 PF04545.16 ABK70972.1 - 0.037 13.5 0.6 0.21 11.1 0.2 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 LexA_DNA_bind PF01726.16 ABK70972.1 - 0.039 13.7 0.0 0.095 12.5 0.0 1.6 1 0 0 1 1 1 0 LexA DNA binding domain HTH_28 PF13518.6 ABK70972.1 - 0.056 13.6 0.4 0.056 13.6 0.4 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain Put_DNA-bind_N PF06971.13 ABK70972.1 - 0.09 12.8 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus MarR_2 PF12802.7 ABK70972.1 - 0.097 12.6 2.2 0.29 11.1 2.2 1.8 1 0 0 1 1 1 0 MarR family SpoIIID PF12116.8 ABK70972.1 - 0.12 12.5 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 Stage III sporulation protein D DUF4423 PF14394.6 ABK70972.1 - 0.14 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) HxlR PF01638.17 ABK70972.1 - 0.22 11.4 0.0 2.9 7.8 0.0 2.1 2 0 0 2 2 2 0 HxlR-like helix-turn-helix CRISPR_Cse2 PF09485.10 ABK70973.1 - 0.0081 16.7 0.0 0.012 16.1 0.0 1.2 1 0 0 1 1 1 1 CRISPR-associated protein Cse2 (CRISPR_cse2) DUF4235 PF14019.6 ABK70973.1 - 0.014 15.5 2.9 0.3 11.2 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4235) DUF5501 PF17605.2 ABK70973.1 - 0.029 14.8 0.0 0.048 14.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5501) GTP_EFTU_D4 PF14578.6 ABK70973.1 - 0.044 13.7 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu domain 4 CwsA PF10814.8 ABK70973.1 - 0.064 13.4 2.0 0.12 12.6 1.3 1.9 1 1 1 2 2 2 0 Cell wall synthesis protein CwsA DUF4381 PF14316.6 ABK70973.1 - 0.11 12.7 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Pex14_N PF04695.13 ABK70973.1 - 2.9 8.5 5.3 0.71 10.5 2.0 1.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Abhydrolase_6 PF12697.7 ABK70974.1 - 1.7e-20 74.6 9.2 2.1e-20 74.3 9.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ABK70974.1 - 2.1e-20 73.4 0.1 4.1e-20 72.5 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ABK70974.1 - 5.7e-10 38.9 0.0 1e-09 38.1 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF3530 PF12048.8 ABK70974.1 - 0.035 13.5 0.2 0.24 10.8 0.0 2.1 2 1 0 3 3 3 0 Protein of unknown function (DUF3530) Chlorophyllase PF07224.11 ABK70974.1 - 0.12 11.4 0.0 0.19 10.7 0.0 1.4 1 1 0 1 1 1 0 Chlorophyllase LigA PF07746.11 ABK70974.1 - 0.13 12.5 0.0 0.73 10.0 0.0 1.9 2 0 0 2 2 2 0 Aromatic-ring-opening dioxygenase LigAB, LigA subunit FSH1 PF03959.13 ABK70974.1 - 0.13 11.9 0.0 0.45 10.1 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Chlorophyllase2 PF12740.7 ABK70974.1 - 0.13 11.1 0.0 0.28 10.1 0.0 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme DLH PF01738.18 ABK70974.1 - 0.14 11.7 0.0 2.7 7.5 0.0 2.6 2 1 0 2 2 2 0 Dienelactone hydrolase family Glyco_hydro_4 PF02056.16 ABK70975.1 - 9.8e-59 198.0 0.0 1.4e-58 197.4 0.0 1.2 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase Glyco_hydro_4C PF11975.8 ABK70975.1 - 1.1e-55 188.9 0.0 1.5e-55 188.5 0.0 1.2 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase C-terminal domain Ldh_1_N PF00056.23 ABK70975.1 - 0.098 12.7 0.0 9 6.4 0.0 2.3 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain p450 PF00067.22 ABK70976.1 - 5.5e-25 88.0 0.0 1.1e-21 77.1 0.0 3.0 2 1 0 2 2 2 2 Cytochrome P450 Wzy_C PF04932.15 ABK70977.1 - 1.3e-08 34.7 4.8 1.3e-08 34.7 4.8 4.6 3 1 2 5 5 5 2 O-Antigen ligase TraX PF05857.11 ABK70977.1 - 4.3 7.3 11.5 3.9 7.5 0.1 3.1 3 0 0 3 3 3 0 TraX protein AA_kinase PF00696.28 ABK70978.1 - 6.9e-32 111.0 0.2 8.1e-32 110.7 0.2 1.1 1 0 0 1 1 1 1 Amino acid kinase family AMP-binding PF00501.28 ABK70979.1 - 7e-71 239.0 1.5 1e-69 235.2 0.6 2.6 2 1 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK70979.1 - 1.6e-20 73.9 0.2 1.6e-20 73.9 0.2 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GDE_N PF12439.8 ABK70981.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme N terminal Bac_luciferase PF00296.20 ABK70982.1 - 1e-30 107.3 0.1 3.4e-30 105.5 0.1 1.7 1 1 0 1 1 1 1 Luciferase-like monooxygenase Ribosomal_L28 PF00830.19 ABK70983.1 - 1.7e-22 79.4 2.0 2e-22 79.1 2.0 1.0 1 0 0 1 1 1 1 Ribosomal L28 family Abi_C PF14355.6 ABK70984.1 - 0.02 15.0 0.0 0.027 14.6 0.0 1.2 1 0 0 1 1 1 0 Abortive infection C-terminus TPP_enzyme_N PF02776.18 ABK70985.1 - 1.2e-41 142.2 9.2 7.5e-39 133.1 0.3 2.6 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 ABK70985.1 - 4.1e-41 140.3 0.6 7.8e-41 139.4 0.1 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 ABK70985.1 - 1.5e-32 112.2 0.1 2.7e-32 111.4 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 ABK70985.1 - 0.034 13.9 0.1 0.066 12.9 0.1 1.5 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg BcrAD_BadFG PF01869.20 ABK70986.1 - 3.1e-47 161.3 0.3 3.5e-47 161.1 0.3 1.0 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family ROK PF00480.20 ABK70986.1 - 0.0022 17.5 0.0 0.067 12.6 0.0 2.2 2 0 0 2 2 2 1 ROK family DUF3236 PF11576.8 ABK70986.1 - 0.019 14.7 0.0 0.15 11.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3236) FGGY_N PF00370.21 ABK70986.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain ResIII PF04851.15 ABK70987.1 - 3.5e-16 59.7 0.0 6.3e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 ABK70987.1 - 5e-10 39.4 0.0 9.1e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DEAD PF00270.29 ABK70987.1 - 5.4e-07 29.5 0.0 1.4e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 ABK70987.1 - 0.00034 20.4 0.1 0.00099 18.9 0.1 1.8 1 0 0 1 1 1 1 AAA domain Helicase_C PF00271.31 ABK70987.1 - 0.0013 19.0 0.0 0.0029 17.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 ABK70987.1 - 0.0018 17.0 0.0 0.0032 16.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Terminase_6 PF03237.15 ABK70987.1 - 0.0025 17.5 0.0 0.0049 16.6 0.0 1.5 1 0 0 1 1 1 1 Terminase-like family AAA_19 PF13245.6 ABK70987.1 - 0.0055 17.1 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ABK70987.1 - 0.0062 16.8 0.1 0.043 14.1 0.0 2.4 3 1 0 3 3 3 1 AAA domain AAA PF00004.29 ABK70987.1 - 0.01 16.3 0.0 0.03 14.7 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 ABK70987.1 - 0.011 15.1 0.1 0.054 12.9 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.6 ABK70987.1 - 0.02 14.5 0.1 0.02 14.5 0.1 3.3 3 2 1 4 4 4 0 AAA domain AAA_14 PF13173.6 ABK70987.1 - 0.041 13.9 0.0 0.23 11.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ABK70987.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 ABK70987.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Helicase_C_2 PF13307.6 ABK70987.1 - 0.12 12.5 0.1 8.3 6.5 0.0 2.4 1 1 1 2 2 2 0 Helicase C-terminal domain DnaB_C PF03796.15 ABK70987.1 - 0.14 11.5 0.0 0.27 10.5 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Cytochrom_C_asm PF01578.20 ABK70988.1 - 4.7e-46 157.3 10.9 7.7e-46 156.6 10.9 1.3 1 0 0 1 1 1 1 Cytochrome C assembly protein DUF2721 PF11026.8 ABK70988.1 - 0.41 10.5 0.1 0.41 10.5 0.1 3.5 4 1 0 4 4 4 0 Protein of unknown function (DUF2721) MdcE PF06833.11 ABK70989.1 - 6.9e-59 199.1 4.6 6.9e-59 199.1 4.6 2.1 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) Carboxyl_trans PF01039.22 ABK70989.1 - 8e-15 54.4 0.9 9.7e-11 41.0 0.3 2.1 2 0 0 2 2 2 2 Carboxyl transferase domain SelR PF01641.18 ABK70990.1 - 3.3e-48 162.7 0.0 4.1e-48 162.5 0.0 1.1 1 0 0 1 1 1 1 SelR domain DNase-RNase PF02577.14 ABK70991.1 - 1.7e-46 157.1 0.1 2e-46 156.8 0.1 1.1 1 0 0 1 1 1 1 Bifunctional nuclease adh_short_C2 PF13561.6 ABK70992.1 - 5.4e-48 163.6 0.7 6.6e-48 163.3 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK70992.1 - 3.3e-40 137.6 0.9 4.7e-40 137.1 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK70992.1 - 1.8e-11 44.3 0.3 2.8e-11 43.7 0.3 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ABK70992.1 - 1.7e-05 24.8 0.4 2.3e-05 24.3 0.4 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ABK70992.1 - 0.00092 18.7 0.2 0.0028 17.2 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 ABK70992.1 - 0.011 15.3 1.4 0.017 14.7 1.4 1.3 1 0 0 1 1 1 0 NmrA-like family Glyoxalase PF00903.25 ABK70992.1 - 0.024 14.8 0.0 0.055 13.7 0.0 1.5 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily F420_oxidored PF03807.17 ABK70992.1 - 0.05 14.2 0.2 0.44 11.2 0.1 2.4 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Mur_ligase PF01225.25 ABK70992.1 - 0.08 13.3 0.1 0.98 9.8 0.1 2.3 2 0 0 2 2 2 0 Mur ligase family, catalytic domain GDP_Man_Dehyd PF16363.5 ABK70992.1 - 0.14 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase CN_hydrolase PF00795.22 ABK70993.1 - 1.9e-43 148.7 0.0 2.5e-43 148.3 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase LppX_LprAFG PF07161.13 ABK70994.1 - 9e-73 244.2 2.8 1e-72 244.0 2.8 1.0 1 0 0 1 1 1 1 LppX_LprAFG lipoprotein DUF5061 PF16587.5 ABK70994.1 - 0.42 10.7 1.8 6 7.0 0.0 2.5 2 1 0 2 2 2 0 17 kDa common-antigen outer membrane protein LPAM_1 PF08139.12 ABK70994.1 - 3.5 8.3 4.7 8.5 7.1 4.7 1.7 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site AlaDh_PNT_C PF01262.21 ABK70995.1 - 4.3e-84 281.1 0.4 6e-84 280.6 0.4 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 ABK70995.1 - 7.8e-48 162.2 0.3 1.9e-47 161.0 0.1 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain 2-Hacid_dh_C PF02826.19 ABK70995.1 - 1.6e-08 34.1 0.1 3.2e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 ABK70995.1 - 1.2e-05 25.4 0.0 2.4e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 ABK70995.1 - 1.5e-05 24.3 0.4 2.3e-05 23.7 0.4 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 ABK70995.1 - 3.7e-05 23.1 0.1 4.4e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ABK70995.1 - 4.7e-05 23.9 0.3 0.00011 22.6 0.3 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 ABK70995.1 - 5.1e-05 23.5 0.3 0.00012 22.3 0.3 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase HI0933_like PF03486.14 ABK70995.1 - 0.00012 20.9 0.1 0.00019 20.3 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein 3HCDH_N PF02737.18 ABK70995.1 - 0.0011 18.9 3.3 0.0023 17.9 1.8 2.3 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 ABK70995.1 - 0.0018 18.7 0.4 0.0042 17.5 0.2 1.6 2 0 0 2 2 1 1 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.19 ABK70995.1 - 0.0033 16.8 1.1 0.025 13.9 0.9 2.5 2 1 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FAD_binding_2 PF00890.24 ABK70995.1 - 0.015 14.4 1.6 0.025 13.7 1.6 1.3 1 0 0 1 1 1 0 FAD binding domain IlvN PF07991.12 ABK70995.1 - 0.015 14.9 0.3 0.039 13.5 0.3 1.7 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 ABK70995.1 - 0.022 15.0 0.1 0.05 13.9 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_8 PF13450.6 ABK70995.1 - 0.025 14.8 0.4 0.081 13.2 0.4 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 ABK70995.1 - 0.032 13.6 3.0 0.045 13.1 3.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF364 PF04016.12 ABK70995.1 - 0.045 13.3 0.1 1.1 8.8 0.0 2.6 3 0 0 3 3 3 0 Putative heavy-metal chelation F420_oxidored PF03807.17 ABK70995.1 - 0.082 13.5 2.5 0.1 13.2 0.5 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 ABK70995.1 - 0.089 12.9 0.6 0.22 11.6 0.6 1.6 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 ABK70995.1 - 0.12 12.0 0.8 1.4 8.5 0.8 2.2 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 ABK70995.1 - 0.12 12.4 0.5 12 5.8 1.1 2.7 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAS PF03059.16 ABK70995.1 - 0.19 11.0 0.0 0.33 10.3 0.0 1.3 1 0 0 1 1 1 0 Nicotianamine synthase protein ThiF PF00899.21 ABK70995.1 - 1.5 8.1 3.7 1.7 7.9 0.6 2.3 3 0 0 3 3 3 0 ThiF family ENOD93 PF03386.14 ABK70996.1 - 0.066 13.1 0.2 0.12 12.3 0.2 1.4 1 0 0 1 1 1 0 Early nodulin 93 ENOD93 protein DUF2165 PF09933.9 ABK70996.1 - 0.16 12.0 3.1 0.24 11.4 1.8 1.7 2 0 0 2 2 2 0 Predicted small integral membrane protein (DUF2165) DUF4131 PF13567.6 ABK70996.1 - 0.36 10.5 3.4 0.37 10.4 1.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Phage_holin_3_6 PF07332.11 ABK70996.1 - 0.38 10.8 13.3 2.9 8.0 0.2 2.1 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III ABC1 PF03109.16 ABK70997.1 - 3.9e-33 114.1 0.0 7.9e-33 113.1 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 ABK70997.1 - 2.8e-05 24.2 4.0 9.7e-05 22.4 0.2 2.8 1 1 1 3 3 3 1 Phosphotransferase enzyme family NifU PF01106.17 ABK70998.1 - 1.3e-17 63.7 0.0 2.9e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 NifU-like domain zinc_ribbon_5 PF13719.6 ABK70998.1 - 0.036 13.8 0.7 2.7 7.8 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 ABK70998.1 - 0.8 9.9 2.7 0.74 10.0 0.3 2.2 2 1 0 2 2 2 0 Zinc ribbon domain Porin_4 PF13609.6 ABK70999.1 - 0.029 14.1 0.1 0.031 14.0 0.1 1.1 1 0 0 1 1 1 0 Gram-negative porin DUF2694 PF10904.8 ABK71000.1 - 0.032 14.3 0.2 0.05 13.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2694) SHMT PF00464.19 ABK71001.1 - 1.2e-123 412.7 0.1 5e-95 318.4 0.1 2.3 2 1 0 2 2 2 2 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 ABK71001.1 - 2.2e-08 33.7 0.0 3.6e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II ECH_1 PF00378.20 ABK71003.1 - 1.2e-36 126.3 0.0 1.4e-36 126.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK71003.1 - 6.6e-24 85.0 0.0 7.7e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Glyoxalase PF00903.25 ABK71004.1 - 2.8e-16 59.9 0.0 3.2e-16 59.7 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ABK71004.1 - 7.7e-06 26.7 0.1 1.3e-05 25.9 0.1 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 ABK71004.1 - 0.00046 20.4 0.0 0.00068 19.9 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily GlutR_N PF05201.15 ABK71005.1 - 1.7e-44 151.2 2.6 2.8e-44 150.4 2.6 1.4 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.20 ABK71005.1 - 1.1e-27 96.7 0.0 2.6e-27 95.6 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.20 ABK71005.1 - 4.3e-22 78.4 0.2 1.4e-21 76.7 0.1 2.0 2 0 0 2 2 2 1 Glutamyl-tRNAGlu reductase, dimerisation domain Glu_dehyd_C PF16912.5 ABK71005.1 - 8.4e-06 25.4 2.8 1.8e-05 24.3 0.9 2.3 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus ApbA PF02558.16 ABK71005.1 - 2.4e-05 24.0 0.4 5.2e-05 22.9 0.4 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 ABK71005.1 - 0.00068 19.8 0.4 0.00068 19.8 0.4 2.3 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 ABK71005.1 - 0.0091 16.3 2.3 0.011 15.9 0.6 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 ABK71005.1 - 0.0092 16.5 0.4 0.045 14.3 0.4 2.3 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 ABK71005.1 - 0.031 14.2 0.9 0.031 14.2 0.9 2.4 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 ABK71005.1 - 0.16 11.3 3.3 0.61 9.4 2.2 2.2 2 0 0 2 2 2 0 ThiF family NAD_binding_10 PF13460.6 ABK71005.1 - 0.18 11.6 12.2 0.021 14.7 4.1 2.8 2 1 1 3 3 3 0 NAD(P)H-binding Pro_isomerase PF00160.21 ABK71006.1 - 3.1e-25 89.3 0.0 4.3e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4519 PF15012.6 ABK71006.1 - 0.15 12.3 0.6 0.24 11.6 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Arginosuc_synth PF00764.19 ABK71007.1 - 2.9e-186 619.4 0.0 3.3e-186 619.2 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 ABK71007.1 - 0.0049 16.4 0.0 0.0076 15.8 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 ABK71007.1 - 0.062 12.9 0.0 0.11 12.1 0.0 1.4 1 1 0 1 1 1 0 Asparagine synthase tRNA_Me_trans PF03054.16 ABK71007.1 - 0.25 10.1 0.2 0.36 9.6 0.2 1.2 1 0 0 1 1 1 0 tRNA methyl transferase adh_short_C2 PF13561.6 ABK71008.1 - 6.8e-58 196.0 3.2 9e-58 195.6 3.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK71008.1 - 2.8e-52 177.0 1.1 3.6e-52 176.7 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK71008.1 - 2.6e-19 69.8 0.4 1.4e-18 67.4 0.4 1.8 2 0 0 2 2 2 1 KR domain THF_DHG_CYH_C PF02882.19 ABK71008.1 - 0.0014 18.0 0.1 0.0023 17.3 0.1 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3Beta_HSD PF01073.19 ABK71008.1 - 0.0064 15.5 0.4 0.0091 15.0 0.4 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.18 ABK71008.1 - 0.0082 16.0 0.5 0.014 15.3 0.5 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 ABK71008.1 - 0.07 12.6 0.2 0.1 12.1 0.2 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF4192 PF13830.6 ABK71009.1 - 3.5e-80 270.5 30.4 4.1e-80 270.2 30.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4192) ABC_tran PF00005.27 ABK71010.1 - 3.2e-45 154.0 0.1 2.3e-23 83.2 0.0 2.9 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 ABK71010.1 - 2.5e-24 86.6 1.5 1.8e-06 28.0 0.0 4.1 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK71010.1 - 4.9e-10 39.2 0.1 0.034 13.6 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 ABK71010.1 - 2.8e-08 33.9 0.1 0.0095 16.2 0.1 3.3 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit ABC_tran_Xtn PF12848.7 ABK71010.1 - 8.7e-08 32.1 4.9 8.7e-08 32.1 4.9 1.6 2 0 0 2 2 1 1 ABC transporter AAA_23 PF13476.6 ABK71010.1 - 2.8e-05 24.7 0.8 0.066 13.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 ABK71010.1 - 5e-05 23.8 0.3 1.3 9.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 ABK71010.1 - 0.0001 22.0 0.1 0.21 11.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ABK71010.1 - 0.00018 21.6 0.0 0.67 10.1 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase DLIC PF05783.11 ABK71010.1 - 0.00019 20.4 1.5 0.0088 14.9 0.0 2.9 3 0 0 3 3 3 1 Dynein light intermediate chain (DLIC) AAA_22 PF13401.6 ABK71010.1 - 0.00044 20.5 2.3 0.42 10.9 0.1 3.3 2 2 0 2 2 2 1 AAA domain Arf PF00025.21 ABK71010.1 - 0.0005 19.6 0.1 0.011 15.2 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_13 PF13166.6 ABK71010.1 - 0.00054 18.7 4.3 0.12 11.0 0.0 3.5 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.6 ABK71010.1 - 0.0011 19.2 5.3 0.19 11.9 0.1 4.0 3 1 0 3 3 3 1 AAA domain SRP54 PF00448.22 ABK71010.1 - 0.0015 18.2 1.2 1.1 8.8 0.1 2.5 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_15 PF13175.6 ABK71010.1 - 0.0024 17.7 0.0 2.9 7.5 0.0 2.8 3 0 0 3 3 3 2 AAA ATPase domain DUF3584 PF12128.8 ABK71010.1 - 0.0031 15.1 13.0 0.016 12.7 0.2 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF3584) NACHT PF05729.12 ABK71010.1 - 0.006 16.5 1.3 0.52 10.2 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 ABK71010.1 - 0.0069 16.8 0.5 4.4 7.7 0.1 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 ABK71010.1 - 0.012 15.4 0.6 6 6.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain Herpes_UL36 PF03586.13 ABK71010.1 - 0.014 14.7 1.2 0.026 13.9 1.2 1.4 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein Zeta_toxin PF06414.12 ABK71010.1 - 0.016 14.5 0.6 1.7 7.8 0.1 2.6 2 0 0 2 2 2 0 Zeta toxin RsgA_GTPase PF03193.16 ABK71010.1 - 0.017 15.0 0.3 1.9 8.3 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase RuvB_N PF05496.12 ABK71010.1 - 0.024 14.4 0.1 1.5 8.5 0.0 2.6 3 0 0 3 3 2 0 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 ABK71010.1 - 0.024 14.6 0.9 5.6 7.0 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 ABK71010.1 - 0.03 14.1 0.7 6.7 6.5 0.2 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 ABK71010.1 - 0.04 14.1 9.3 1.5 9.1 0.0 3.8 4 0 0 4 4 4 0 AAA domain cobW PF02492.19 ABK71010.1 - 0.057 13.0 1.4 1.3 8.6 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 ABK71010.1 - 0.091 13.1 12.3 0.084 13.2 0.4 3.2 3 2 0 3 3 3 0 AAA ATPase domain Roc PF08477.13 ABK71010.1 - 0.13 12.5 0.0 6.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 ABK71010.1 - 0.5 10.1 10.9 1.5 8.5 0.4 3.2 3 1 0 3 3 2 0 AAA domain AAA_27 PF13514.6 ABK71010.1 - 5.2 6.6 7.7 5.1 6.6 0.0 3.1 4 0 0 4 4 3 0 AAA domain Sigma70_r2 PF04542.14 ABK71011.1 - 2.3e-17 62.5 3.3 6.6e-16 57.8 3.3 2.5 1 1 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 ABK71011.1 - 7.4e-15 54.2 0.3 1.4e-14 53.3 0.3 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 ABK71011.1 - 4.1e-12 45.6 0.2 6.9e-12 44.9 0.2 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 ABK71011.1 - 0.00011 22.2 0.2 0.00016 21.6 0.1 1.3 1 1 0 1 1 1 1 ECF sigma factor GerE PF00196.19 ABK71011.1 - 0.00074 19.0 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_23 PF13384.6 ABK71011.1 - 0.0012 18.6 0.1 0.0034 17.1 0.1 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 ABK71011.1 - 0.0019 17.9 0.1 0.0044 16.7 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Phage_antitermQ PF06530.12 ABK71011.1 - 0.014 15.3 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Phage antitermination protein Q HTH_40 PF14493.6 ABK71011.1 - 0.064 13.7 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Acyl-CoA_dh_1 PF00441.24 ABK71012.1 - 3e-26 92.4 4.0 4.2e-26 92.0 4.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 ABK71012.1 - 9.5e-09 35.6 9.9 9.5e-09 35.6 9.9 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK71012.1 - 2.1e-07 31.6 0.0 7.2e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Prenyltransf PF01255.19 ABK71014.1 - 2e-72 243.4 0.3 2.6e-72 243.0 0.3 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Acyl-CoA_dh_2 PF08028.11 ABK71015.1 - 1e-12 48.5 6.9 2.2e-12 47.4 6.9 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK71015.1 - 4.3e-11 42.9 0.1 1.4e-10 41.2 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 ABK71015.1 - 0.00013 22.2 2.8 0.00024 21.3 2.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Lipoprotein_Ltp PF07553.11 ABK71016.1 - 5.4e-28 97.0 1.7 7.8e-13 48.5 0.3 2.1 2 0 0 2 2 2 2 Host cell surface-exposed lipoprotein DUF1640 PF07798.11 ABK71016.1 - 0.076 13.1 0.0 0.81 9.7 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) CSTF1_dimer PF16699.5 ABK71016.1 - 0.13 12.1 0.3 7.2 6.5 0.0 2.5 3 0 0 3 3 3 0 Cleavage stimulation factor subunit 1, dimerisation domain MurB_C PF02873.16 ABK71016.1 - 0.13 12.3 0.0 0.71 9.9 0.0 1.8 1 1 1 2 2 2 0 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain AMP-binding PF00501.28 ABK71017.1 - 1.5e-71 241.3 0.0 1.8e-71 240.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C_2 PF14535.6 ABK71017.1 - 0.15 12.4 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Rsm22 PF09243.10 ABK71018.1 - 0.0046 16.3 0.0 0.0073 15.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 ABK71018.1 - 0.0085 15.9 0.0 0.02 14.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain DUF2398 PF09661.10 ABK71018.1 - 0.044 13.0 0.1 0.11 11.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2398) Methyltransf_25 PF13649.6 ABK71018.1 - 0.068 13.9 0.1 1.1 10.0 0.1 2.7 1 1 0 1 1 1 0 Methyltransferase domain 3HCDH_N PF02737.18 ABK71018.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_31 PF13847.6 ABK71018.1 - 0.2 11.4 0.0 0.41 10.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain CTP_transf_like PF01467.26 ABK71019.1 - 4.6e-31 107.9 0.0 5.5e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like YCII PF03795.14 ABK71020.1 - 8e-22 77.5 0.3 1.7e-12 47.6 0.1 2.1 2 0 0 2 2 2 2 YCII-related domain ABC_tran PF00005.27 ABK71021.1 - 2.8e-27 95.9 0.0 3.9e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK71021.1 - 1.4e-08 34.9 0.0 0.00032 20.6 0.2 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK71021.1 - 4.6e-07 29.5 0.0 2.6e-06 27.0 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ABK71021.1 - 2.9e-05 23.7 0.1 5.9e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Dynamin_N PF00350.23 ABK71021.1 - 0.00019 21.6 0.0 0.00026 21.1 0.0 1.2 1 0 0 1 1 1 1 Dynamin family AAA_23 PF13476.6 ABK71021.1 - 0.0014 19.1 0.0 0.0016 18.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ABK71021.1 - 0.0018 18.7 0.0 0.0022 18.4 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 ABK71021.1 - 0.0035 17.3 0.0 0.0073 16.2 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase MukB PF04310.12 ABK71021.1 - 0.0048 16.7 0.3 0.016 15.0 0.1 1.8 2 0 0 2 2 2 1 MukB N-terminal MMR_HSR1 PF01926.23 ABK71021.1 - 0.008 16.3 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 ABK71021.1 - 0.016 15.5 0.0 0.13 12.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 ABK71021.1 - 0.019 13.8 0.4 2.6 6.8 0.1 2.5 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_27 PF13514.6 ABK71021.1 - 0.023 14.3 0.1 0.048 13.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 ABK71021.1 - 0.025 14.3 0.0 0.037 13.7 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain DUF815 PF05673.13 ABK71021.1 - 0.031 13.5 0.0 0.049 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 ABK71021.1 - 0.032 14.0 0.2 0.58 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ABK71021.1 - 0.054 13.1 0.8 0.28 10.7 0.8 2.1 1 1 0 1 1 1 0 AAA domain Hydrolase PF00702.26 ABK71021.1 - 0.056 13.7 0.1 5.7 7.2 0.0 2.3 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase IstB_IS21 PF01695.17 ABK71021.1 - 0.076 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA PF00004.29 ABK71021.1 - 0.11 12.9 0.0 0.75 10.2 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IIGP PF05049.13 ABK71021.1 - 0.22 10.5 0.1 0.34 9.9 0.1 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) DUF202 PF02656.15 ABK71022.1 - 9e-09 35.7 5.7 9e-09 35.7 5.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) YwiC PF14256.6 ABK71022.1 - 0.00037 20.8 2.7 0.00037 20.8 2.7 1.9 2 0 0 2 2 2 1 YwiC-like protein DUF2946 PF11162.8 ABK71022.1 - 0.034 14.8 0.5 0.052 14.2 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) LPAM_1 PF08139.12 ABK71022.1 - 0.067 13.7 0.3 0.067 13.7 0.3 3.5 3 1 0 3 3 3 0 Prokaryotic membrane lipoprotein lipid attachment site Aldedh PF00171.22 ABK71023.1 - 1.7e-160 534.6 0.0 1.9e-160 534.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SSF PF00474.17 ABK71024.1 - 2.3e-96 323.2 31.1 2.3e-96 323.2 31.1 1.6 2 0 0 2 2 2 1 Sodium:solute symporter family adh_short PF00106.25 ABK71025.1 - 2.4e-50 170.7 1.4 3.9e-50 170.0 1.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK71025.1 - 4.9e-43 147.4 4.5 8.3e-43 146.6 4.5 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Abhydrolase_1 PF00561.20 ABK71025.1 - 3.4e-21 76.0 0.8 1.7e-20 73.8 0.8 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ABK71025.1 - 2.8e-09 36.6 0.1 9.6e-09 34.9 0.1 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 KR PF08659.10 ABK71025.1 - 4.9e-09 36.3 0.6 1e-08 35.3 0.6 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK71025.1 - 6.1e-08 32.4 0.1 1.1e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ABC_tran PF00005.27 ABK71026.1 - 1.7e-29 103.1 0.0 2.5e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK71026.1 - 1.6e-08 34.7 0.0 0.0048 16.7 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ABK71026.1 - 0.0017 18.8 0.2 0.0032 17.9 0.2 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_27 PF13514.6 ABK71026.1 - 0.0021 17.7 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ABK71026.1 - 0.0028 17.4 1.0 0.0073 16.0 1.0 2.0 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 ABK71026.1 - 0.022 14.5 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 ABK71026.1 - 0.04 14.4 0.0 0.051 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ABK71026.1 - 0.048 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRP54 PF00448.22 ABK71026.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MarR PF01047.22 ABK71027.1 - 1.9e-12 46.9 0.2 7.4e-12 45.0 0.0 1.9 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.7 ABK71027.1 - 3.7e-12 45.9 1.9 8.4e-12 44.8 1.9 1.6 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 ABK71027.1 - 4.6e-12 46.3 0.2 7.9e-12 45.5 0.2 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 ABK71027.1 - 5.4e-07 29.3 2.6 2.3e-06 27.3 2.6 2.2 1 1 0 1 1 1 1 IclR helix-turn-helix domain HTH_24 PF13412.6 ABK71027.1 - 0.00036 20.0 0.1 0.00056 19.4 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 ABK71027.1 - 0.0014 18.6 0.6 0.0033 17.4 0.2 1.9 2 1 0 2 2 2 1 Crp-like helix-turn-helix domain TrmB PF01978.19 ABK71027.1 - 0.0018 18.1 0.2 0.0032 17.3 0.0 1.5 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.7 ABK71027.1 - 0.0039 17.2 0.6 0.0085 16.1 0.2 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain SMC_ScpB PF04079.16 ABK71027.1 - 0.0046 16.6 0.0 0.008 15.8 0.0 1.3 1 0 0 1 1 1 1 Segregation and condensation complex subunit ScpB Fe_dep_repress PF01325.19 ABK71027.1 - 0.0065 16.6 0.1 0.016 15.4 0.0 1.6 2 0 0 2 2 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_5 PF01022.20 ABK71027.1 - 0.015 15.2 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family FaeA PF04703.12 ABK71027.1 - 0.037 14.4 0.0 0.092 13.1 0.0 1.6 2 0 0 2 2 2 0 FaeA-like protein Rrf2 PF02082.20 ABK71027.1 - 0.037 14.4 0.2 0.14 12.6 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator HTH_AsnC-type PF13404.6 ABK71027.1 - 0.056 13.3 0.5 0.15 11.9 0.5 1.8 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain GP57 PF17594.2 ABK71027.1 - 0.07 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Phage Tail fiber assembly helper gene product 57 RuvB_C PF05491.13 ABK71027.1 - 0.087 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 RuvB C-terminal winged helix domain FeoC PF09012.10 ABK71027.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 FeoC like transcriptional regulator SSF PF00474.17 ABK71028.1 - 2e-37 129.1 34.0 2e-25 89.5 12.0 2.4 2 1 0 2 2 2 2 Sodium:solute symporter family CN_hydrolase PF00795.22 ABK71029.1 - 1e-30 106.9 0.0 1.2e-30 106.7 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PRiA4_ORF3 PF07929.11 ABK71030.1 - 2.1e-51 174.1 0.0 2.5e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein HTH_Tnp_1 PF01527.20 ABK71031.1 - 4.3e-07 30.1 3.8 2e-06 28.0 3.8 2.0 1 1 0 1 1 1 1 Transposase HTH_23 PF13384.6 ABK71031.1 - 0.0028 17.4 0.4 0.0089 15.8 0.4 1.9 1 1 0 1 1 1 1 Homeodomain-like domain HMMR_N PF15905.5 ABK71031.1 - 0.015 14.8 0.2 0.024 14.1 0.1 1.4 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal HTH_28 PF13518.6 ABK71031.1 - 0.026 14.6 0.4 0.053 13.7 0.4 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_terminase PF10668.9 ABK71031.1 - 0.062 13.3 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Phage terminase small subunit Lactamase_B PF00753.27 ABK71032.1 - 2.8e-20 73.2 8.5 3.6e-20 72.8 8.5 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 ABK71032.1 - 0.0058 16.5 0.7 0.0088 15.9 0.2 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 ABK71032.1 - 0.015 14.8 2.5 0.031 13.8 2.5 1.6 1 1 0 1 1 1 0 Beta-lactamase superfamily domain SBP_bac_11 PF13531.6 ABK71033.1 - 2.3e-35 122.4 0.2 2.9e-35 122.1 0.2 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 ABK71033.1 - 1.8e-13 50.9 0.1 3e-13 50.2 0.1 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 ABK71033.1 - 8.9e-13 48.9 2.0 1.7e-12 47.9 2.0 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 ABK71033.1 - 1.5e-10 41.0 0.1 2.1e-10 40.4 0.1 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein PBP_like PF12727.7 ABK71033.1 - 0.0014 17.8 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 PBP superfamily domain Aldedh PF00171.22 ABK71035.1 - 2.7e-142 474.5 0.0 3.1e-142 474.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Trp_oprn_chp PF09534.10 ABK71036.1 - 0.0013 18.5 3.1 0.0019 18.0 3.1 1.2 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) FAD_binding_3 PF01494.19 ABK71037.1 - 1.1e-16 61.1 0.0 1.5e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ABK71037.1 - 4.2e-06 26.6 2.1 0.0084 15.7 0.1 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 ABK71037.1 - 0.0014 19.2 0.0 0.0033 17.9 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ABK71037.1 - 0.0021 18.2 0.1 0.007 16.6 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 ABK71037.1 - 0.0061 16.2 0.3 0.019 14.6 0.1 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 ABK71037.1 - 0.029 13.6 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase LCM PF04072.14 ABK71038.1 - 3e-13 50.2 0.0 1.1e-12 48.3 0.0 1.9 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase bPH_6 PF10756.9 ABK71039.1 - 2.2e-24 85.3 1.5 3.6e-24 84.6 1.5 1.3 1 0 0 1 1 1 1 Bacterial PH domain ABC_tran PF00005.27 ABK71040.1 - 7.4e-30 104.2 0.0 1.1e-29 103.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 ABK71040.1 - 1.1e-05 25.9 0.1 1.5e-05 25.4 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 ABK71040.1 - 1.6e-05 24.5 0.1 3.4e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 ABK71040.1 - 2.7e-05 24.6 0.1 0.00027 21.4 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 ABK71040.1 - 0.00054 20.2 0.1 0.0029 17.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ABK71040.1 - 0.00057 19.8 0.1 0.0011 19.0 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 ABK71040.1 - 0.00068 20.2 0.2 0.0011 19.5 0.2 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ABK71040.1 - 0.00075 19.7 0.0 0.0016 18.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ABK71040.1 - 0.00079 19.2 0.2 0.001 18.8 0.2 1.4 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 ABK71040.1 - 0.00084 19.2 0.1 0.0018 18.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK71040.1 - 0.0021 17.5 0.1 1.2 8.5 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 ABK71040.1 - 0.0038 17.2 0.1 0.0087 16.0 0.1 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain Mg_chelatase PF01078.21 ABK71040.1 - 0.0072 15.7 0.0 0.015 14.7 0.0 1.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_15 PF13175.6 ABK71040.1 - 0.02 14.6 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 ABK71040.1 - 0.025 15.1 0.0 0.039 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ABK71040.1 - 0.027 14.5 0.0 0.092 12.8 0.0 1.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_5 PF07728.14 ABK71040.1 - 0.036 14.0 0.5 0.076 13.0 0.2 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ABK71040.1 - 0.048 13.9 0.3 0.098 12.9 0.3 1.9 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 ABK71040.1 - 0.067 13.1 0.5 0.14 12.1 0.1 1.7 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 ABK71040.1 - 0.068 13.6 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 ABK71040.1 - 0.071 12.7 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.15 ABK71040.1 - 0.12 11.2 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_19 PF13245.6 ABK71040.1 - 0.17 12.3 0.7 0.32 11.3 0.7 1.5 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 ABK71040.1 - 0.17 11.8 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase ATPase_2 PF01637.18 ABK71040.1 - 0.18 11.7 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 ABK71040.1 - 0.23 11.4 0.3 3.2 7.6 0.2 2.1 2 0 0 2 2 2 0 NTPase Acyl-CoA_dh_2 PF08028.11 ABK71041.1 - 9.4e-23 81.0 12.9 1.6e-22 80.2 12.9 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK71041.1 - 2e-05 24.7 0.0 3.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ABK71041.1 - 6.8e-05 23.5 0.0 0.00022 21.9 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 ABK71041.1 - 7.5e-05 23.0 5.8 0.00011 22.4 5.8 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF5353 PF17304.2 ABK71041.1 - 0.043 13.5 0.5 0.16 11.7 0.5 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5353) DUF4257 PF14074.6 ABK71041.1 - 0.09 13.0 0.2 0.26 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4257) NYN PF01936.18 ABK71042.1 - 1.8e-05 25.2 0.0 2.6e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 NYN domain HisKA_3 PF07730.13 ABK71043.1 - 7.4e-16 58.4 1.8 2.4e-15 56.8 1.8 1.9 1 0 0 1 1 1 1 Histidine kinase Sensor PF13796.6 ABK71043.1 - 1.1e-08 35.4 16.6 1.1e-08 35.4 16.6 1.7 2 0 0 2 2 2 1 Putative sensor HATPase_c_2 PF13581.6 ABK71043.1 - 7.7e-06 25.9 0.1 1.4e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 ABK71043.1 - 0.0038 17.7 0.0 0.021 15.3 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase T2SSM_b PF10741.9 ABK71043.1 - 0.048 13.5 0.3 0.19 11.5 0.0 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b HemY_N PF07219.13 ABK71043.1 - 0.81 9.9 6.4 0.28 11.4 0.9 2.7 2 0 0 2 2 2 0 HemY protein N-terminus PRiA4_ORF3 PF07929.11 ABK71044.1 - 2.1e-51 174.1 0.0 2.5e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein DDE_3 PF13358.6 ABK71046.1 - 1.9e-24 86.1 0.0 2.9e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.6 ABK71046.1 - 3.9e-15 55.6 0.2 1.5e-14 53.8 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 ABK71046.1 - 1.2e-12 47.8 4.7 3.6e-11 43.0 0.2 2.8 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_23 PF13384.6 ABK71046.1 - 2.4e-11 43.1 1.9 1.2e-10 40.9 0.0 2.6 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 ABK71046.1 - 8.3e-10 39.1 0.1 3.6e-09 37.1 0.0 2.1 1 1 1 2 2 2 1 Homeodomain-like domain HTH_50 PF18024.1 ABK71046.1 - 6e-07 29.0 0.1 1.7e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 ABK71046.1 - 2.7e-06 27.8 0.1 6.2e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 leucine-zipper of insertion element IS481 HTH_Tnp_1 PF01527.20 ABK71046.1 - 0.028 14.7 0.1 0.096 13.0 0.0 1.9 2 0 0 2 2 2 0 Transposase HTH_1 PF00126.27 ABK71046.1 - 0.058 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_6 PF01418.17 ABK71046.1 - 0.079 12.9 0.0 2.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family rve_2 PF13333.6 ABK71046.1 - 0.1 12.8 0.0 1.3 9.2 0.0 2.2 2 0 0 2 2 2 0 Integrase core domain Erf4 PF10256.9 ABK71046.1 - 0.18 11.9 0.0 2.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family DAO PF01266.24 ABK71047.1 - 1.2e-52 179.7 10.8 1.2e-52 179.7 10.8 1.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 ABK71047.1 - 1.1e-07 31.3 0.1 2.2e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 ABK71047.1 - 2.5e-05 24.4 1.5 0.00028 21.0 0.2 3.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ABK71047.1 - 0.0015 17.9 0.0 0.038 13.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ABK71047.1 - 0.0019 17.4 3.7 0.0028 16.8 3.7 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 ABK71047.1 - 0.021 15.4 0.0 9 6.9 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ABK71047.1 - 0.057 12.7 0.0 0.23 10.6 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain Isochorismatase PF00857.20 ABK71048.1 - 3.7e-33 115.1 0.0 4.4e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Herpes_UL17 PF04559.12 ABK71048.1 - 0.11 11.2 0.1 0.16 10.7 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL17 protein FolB PF02152.18 ABK71049.1 - 3.4e-33 114.5 0.0 3.7e-33 114.4 0.0 1.0 1 0 0 1 1 1 1 Dihydroneopterin aldolase Rieske PF00355.26 ABK71051.1 - 2.6e-14 52.9 0.2 3.8e-14 52.4 0.2 1.2 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain TAT_signal PF10518.9 ABK71051.1 - 0.012 15.5 1.9 0.025 14.4 1.9 1.5 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence adh_short PF00106.25 ABK71052.1 - 2.4e-50 170.7 0.9 3.6e-50 170.1 0.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK71052.1 - 7.5e-37 127.1 5.9 9.9e-37 126.7 5.9 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 ABK71052.1 - 2.1e-11 44.1 6.3 2.1e-11 44.1 6.3 1.5 1 1 1 2 2 2 1 NAD(P)H-binding KR PF08659.10 ABK71052.1 - 3.7e-08 33.5 2.1 5.5e-08 32.9 2.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK71052.1 - 7.1e-08 32.2 1.0 2e-07 30.8 1.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ABK71052.1 - 0.0011 18.2 1.2 0.0029 16.8 0.6 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain NmrA PF05368.13 ABK71052.1 - 0.0026 17.3 0.2 0.066 12.8 0.5 2.1 2 0 0 2 2 2 1 NmrA-like family CytB6-F_Fe-S PF08802.10 ABK71052.1 - 0.046 13.8 0.1 0.046 13.8 0.1 2.6 4 0 0 4 4 4 0 Cytochrome B6-F complex Fe-S subunit ABATE PF07336.11 ABK71053.1 - 1.5e-20 74.1 6.6 1.5e-20 74.1 6.6 1.8 2 0 0 2 2 2 1 Putative stress-induced transcription regulator zf-CGNR PF11706.8 ABK71053.1 - 7.6e-12 44.9 4.5 1.3e-11 44.1 4.5 1.4 1 0 0 1 1 1 1 CGNR zinc finger EamA PF00892.20 ABK71054.1 - 1.5e-32 112.6 37.3 1.1e-17 64.4 17.3 2.0 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 ABK71054.1 - 0.017 14.3 3.1 0.034 13.3 3.1 1.4 1 0 0 1 1 1 0 UAA transporter family TrkA_C PF02080.21 ABK71055.1 - 3.5e-16 58.8 0.6 3.5e-16 58.8 0.6 1.8 2 0 0 2 2 2 1 TrkA-C domain FTSW_RODA_SPOVE PF01098.19 ABK71056.1 - 2.5e-98 329.4 21.6 3.9e-98 328.7 21.6 1.3 1 0 0 1 1 1 1 Cell cycle protein CinA PF02464.17 ABK71057.1 - 1.4e-52 177.3 1.9 1.4e-52 177.3 1.9 1.7 2 0 0 2 2 2 1 Competence-damaged protein MoCF_biosynth PF00994.24 ABK71057.1 - 4.9e-37 126.8 0.2 1.5e-35 122.0 0.0 2.2 2 0 0 2 2 2 2 Probable molybdopterin binding domain N6_Mtase PF02384.16 ABK71058.1 - 3e-12 46.4 0.0 4.4e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase Eco57I PF07669.11 ABK71058.1 - 0.0016 18.9 0.0 0.003 18.1 0.0 1.4 1 0 0 1 1 1 1 Eco57I restriction-modification methylase MTS PF05175.14 ABK71058.1 - 0.0058 16.2 0.0 0.14 11.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Cellulase PF00150.18 ABK71060.1 - 1.1e-05 25.0 0.0 2e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Chlor_dismutase PF06778.12 ABK71061.1 - 1.4e-73 246.6 0.0 1.7e-73 246.4 0.0 1.0 1 0 0 1 1 1 1 Chlorite dismutase B12-binding PF02310.19 ABK71062.1 - 1.1e-21 77.2 2.1 1.2e-21 77.0 2.1 1.1 1 0 0 1 1 1 1 B12 binding domain SOR_SNZ PF01680.17 ABK71063.1 - 8.9e-107 355.5 3.2 1.2e-106 355.1 3.2 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 ABK71063.1 - 6.6e-08 32.2 7.6 1.6e-05 24.3 0.5 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 ABK71063.1 - 0.00015 21.0 0.1 0.043 12.9 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 ABK71063.1 - 0.00049 19.6 0.4 0.012 15.1 0.0 2.7 2 1 0 2 2 2 1 Histidine biosynthesis protein NanE PF04131.14 ABK71063.1 - 0.0024 17.1 2.9 0.023 13.9 0.2 2.6 1 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.21 ABK71063.1 - 0.0033 16.6 0.1 0.078 12.1 0.0 2.2 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase NMO PF03060.15 ABK71063.1 - 0.0035 16.8 0.7 0.0035 16.8 0.7 2.2 2 0 0 2 2 2 1 Nitronate monooxygenase FMN_dh PF01070.18 ABK71063.1 - 0.014 14.4 0.1 0.014 14.4 0.1 1.7 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Glu_synthase PF01645.17 ABK71063.1 - 0.026 13.7 0.3 0.044 12.9 0.3 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase OMPdecase PF00215.24 ABK71063.1 - 0.034 13.7 0.2 3.5 7.1 0.0 2.4 1 1 1 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family TetR_C_27 PF17935.1 ABK71063.1 - 0.08 13.0 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain SpoU_methylase PF00588.19 ABK71064.1 - 3e-29 102.0 0.0 3.3e-29 101.9 0.0 1.0 1 0 0 1 1 1 1 SpoU rRNA Methylase family DUF2934 PF11154.8 ABK71064.1 - 0.091 12.5 0.7 0.19 11.4 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2934) SBP_bac_5 PF00496.22 ABK71065.1 - 8.6e-90 301.4 0.1 1.2e-89 301.0 0.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle LPAM_1 PF08139.12 ABK71065.1 - 0.055 14.0 0.5 0.097 13.2 0.5 1.4 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site SfLAP PF11139.8 ABK71066.1 - 8.6e-78 260.7 15.2 9.8e-78 260.5 15.2 1.0 1 0 0 1 1 1 1 Sap, sulfolipid-1-addressing protein DUF3367 PF11847.8 ABK71066.1 - 0.077 10.9 0.0 0.077 10.9 0.0 2.0 2 0 0 2 2 2 0 Alpha-(1->3)-arabinofuranosyltransferase TetR_C_35 PF18556.1 ABK71067.1 - 2.9e-37 127.0 0.1 8.7e-36 122.2 0.1 2.3 2 0 0 2 2 2 1 Bacterial Tetracyclin repressor, C-terminal domain TetR_N PF00440.23 ABK71067.1 - 8e-09 35.2 0.0 1.5e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_23 PF13384.6 ABK71067.1 - 0.057 13.2 0.2 0.31 10.9 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain LZ_Tnp_IS481 PF13011.6 ABK71067.1 - 0.077 13.5 0.6 0.38 11.3 0.0 2.2 2 0 0 2 2 2 0 leucine-zipper of insertion element IS481 HTH_Tnp_1_2 PF13022.6 ABK71067.1 - 0.15 12.2 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase E1-E2_ATPase PF00122.20 ABK71068.1 - 1e-53 181.5 3.8 1e-53 181.5 3.8 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 ABK71068.1 - 7.5e-49 166.9 11.6 1.9e-48 165.6 9.8 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 ABK71068.1 - 2.8e-15 56.5 0.2 6.8e-14 52.1 0.3 2.8 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 ABK71068.1 - 0.00072 19.4 0.4 0.01 15.6 0.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ABK71068.1 - 0.049 14.0 0.9 0.21 12.0 0.2 2.5 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase FAD_binding_3 PF01494.19 ABK71069.1 - 3.2e-68 230.6 0.0 3.8e-68 230.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ABK71069.1 - 8.3e-06 25.2 0.0 0.013 14.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ABK71069.1 - 9e-06 25.8 0.2 2.5e-05 24.4 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ABK71069.1 - 9.6e-05 22.1 6.7 0.00012 21.8 3.9 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ABK71069.1 - 0.00015 20.6 0.1 0.0016 17.2 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 ABK71069.1 - 0.00017 22.1 0.0 0.014 16.0 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ABK71069.1 - 0.00066 18.8 1.2 0.0026 16.9 1.2 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 ABK71069.1 - 0.00075 18.7 0.2 0.0016 17.6 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 ABK71069.1 - 0.0032 16.8 0.1 0.0046 16.2 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 ABK71069.1 - 0.0042 16.4 0.0 0.007 15.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ABK71069.1 - 0.065 12.4 0.0 0.092 11.9 0.0 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) ApbA PF02558.16 ABK71069.1 - 0.18 11.4 0.2 0.31 10.7 0.2 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Hydrolase_3 PF08282.12 ABK71070.1 - 9.1e-56 189.4 0.0 1e-55 189.3 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 ABK71070.1 - 3.9e-14 52.8 0.1 1.5e-08 34.4 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Trehalose_PPase PF02358.16 ABK71070.1 - 6.7e-05 22.1 0.0 0.038 13.1 0.0 2.1 2 0 0 2 2 2 2 Trehalose-phosphatase Hydrolase PF00702.26 ABK71070.1 - 0.0016 18.8 3.7 0.17 12.2 3.7 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ABK71070.1 - 0.016 15.7 2.4 1.6 9.1 0.0 3.2 2 2 1 3 3 3 0 haloacid dehalogenase-like hydrolase SoxG PF04268.12 ABK71071.1 - 0.53 10.4 3.5 15 5.7 0.1 2.2 2 0 0 2 2 2 0 Sarcosine oxidase, gamma subunit family PALP PF00291.25 ABK71073.1 - 1.1e-73 248.3 6.3 1.2e-73 248.1 6.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACP_syn_III_C PF08541.10 ABK71073.1 - 0.064 13.4 0.2 4.8 7.4 0.0 3.1 4 0 0 4 4 4 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Transgly_assoc PF04226.13 ABK71074.1 - 4.3e-05 23.7 11.4 4.3e-05 23.7 11.4 2.5 2 1 0 2 2 2 1 Transglycosylase associated protein PRD1_DD PF11087.8 ABK71074.1 - 0.046 13.4 2.2 0.046 13.4 2.2 3.2 2 1 1 3 3 3 0 PRD1 phage membrane DNA delivery DUF2070 PF09843.9 ABK71074.1 - 0.32 9.2 6.2 0.38 9.0 6.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ATPase_gene1 PF09527.10 ABK71074.1 - 3.4 7.9 13.9 0.27 11.4 7.6 2.2 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter PHO4 PF01384.20 ABK71074.1 - 4.1 6.4 9.2 6.5 5.7 9.2 1.3 1 1 0 1 1 1 0 Phosphate transporter family Glyoxalase PF00903.25 ABK71075.1 - 5.8e-22 78.3 0.0 3.8e-17 62.7 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ABK71075.1 - 0.0048 17.7 1.4 0.099 13.4 0.0 2.5 2 0 0 2 2 2 1 Glyoxalase-like domain VTC PF09359.10 ABK71077.1 - 1.2e-37 129.9 0.0 3e-37 128.5 0.0 1.6 1 1 0 1 1 1 1 VTC domain Penicillinase_R PF03965.16 ABK71078.1 - 3.1e-30 104.9 0.1 3.6e-30 104.7 0.1 1.0 1 0 0 1 1 1 1 Penicillinase repressor HTH_27 PF13463.6 ABK71078.1 - 0.0054 17.2 0.1 0.17 12.4 0.0 2.2 2 0 0 2 2 2 1 Winged helix DNA-binding domain TrmB PF01978.19 ABK71078.1 - 0.0062 16.4 0.0 0.022 14.6 0.0 1.9 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB GntR PF00392.21 ABK71078.1 - 0.012 15.2 2.3 0.79 9.4 0.5 2.8 2 1 0 2 2 2 0 Bacterial regulatory proteins, gntR family DUF4364 PF14277.6 ABK71078.1 - 0.03 14.1 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) MarR_2 PF12802.7 ABK71078.1 - 0.048 13.6 3.2 0.088 12.7 0.3 2.2 2 0 0 2 2 2 0 MarR family PadR PF03551.14 ABK71078.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.6 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family HTH_AsnC-type PF13404.6 ABK71080.1 - 3.5e-27 94.0 4.2 8.2e-13 48.0 0.1 2.6 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 ABK71080.1 - 1.9e-18 65.7 0.0 7.3e-10 38.3 0.0 2.5 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding AsnC_trans_reg PF01037.21 ABK71080.1 - 1.2e-15 57.2 0.0 8.9e-07 28.8 0.0 2.4 2 0 0 2 2 2 2 Lrp/AsnC ligand binding domain HTH_IclR PF09339.10 ABK71080.1 - 5.6e-08 32.5 1.4 0.00021 21.0 0.2 2.5 2 0 0 2 2 2 2 IclR helix-turn-helix domain MarR_2 PF12802.7 ABK71080.1 - 1e-07 31.7 0.6 0.0028 17.5 0.1 2.6 2 0 0 2 2 2 2 MarR family HTH_Tnp_ISL3 PF13542.6 ABK71080.1 - 9.9e-07 28.1 0.0 2.6e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 MarR PF01047.22 ABK71080.1 - 3.7e-06 26.8 0.1 0.0073 16.2 0.0 2.7 3 0 0 3 3 3 2 MarR family HTH_20 PF12840.7 ABK71080.1 - 6.4e-06 26.1 1.7 0.00029 20.8 0.3 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_DeoR PF08220.12 ABK71080.1 - 3.2e-05 23.6 0.0 5.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 ABK71080.1 - 0.00015 21.6 0.0 0.0006 19.7 0.0 1.9 2 0 0 2 2 2 1 HTH domain Fe_dep_repress PF01325.19 ABK71080.1 - 0.00024 21.3 0.0 0.12 12.6 0.0 2.3 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain HTH_28 PF13518.6 ABK71080.1 - 0.0019 18.3 0.9 1.1 9.4 0.0 2.7 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_23 PF13384.6 ABK71080.1 - 0.0032 17.2 0.2 0.3 10.9 0.0 2.9 2 1 1 3 3 3 1 Homeodomain-like domain TrmB PF01978.19 ABK71080.1 - 0.012 15.4 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_6 PF01418.17 ABK71080.1 - 0.034 14.1 0.0 0.21 11.6 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family HTH_Crp_2 PF13545.6 ABK71080.1 - 0.035 14.1 0.2 0.68 9.9 0.1 2.4 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_29 PF13551.6 ABK71080.1 - 0.057 13.4 1.3 0.96 9.5 0.0 2.7 3 0 0 3 3 3 0 Winged helix-turn helix Sigma70_r4 PF04545.16 ABK71080.1 - 0.23 11.0 0.1 0.23 11.0 0.1 2.1 3 0 0 3 3 3 0 Sigma-70, region 4 FMO-like PF00743.19 ABK71081.1 - 1.4e-19 69.9 0.0 2.3e-18 65.9 0.0 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ABK71081.1 - 3.5e-18 65.9 0.0 6.8e-17 61.7 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ABK71081.1 - 4.5e-13 49.2 0.0 3.6e-12 46.3 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 ABK71081.1 - 1.4e-11 44.2 0.1 2.5e-09 36.8 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 ABK71081.1 - 2.7e-08 33.4 0.0 6.2e-06 25.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ABK71081.1 - 5e-05 23.0 0.1 0.00029 20.5 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 ABK71081.1 - 0.00025 20.5 0.0 0.00039 19.8 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 ABK71081.1 - 0.00031 20.8 0.1 0.088 12.8 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 ABK71081.1 - 0.00039 19.6 0.0 0.00074 18.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 ABK71081.1 - 0.00058 20.4 0.0 0.008 16.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ABK71081.1 - 0.0021 17.4 0.0 0.0037 16.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ABK71081.1 - 0.016 14.0 0.0 0.15 10.7 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 ABK71081.1 - 0.11 11.6 0.1 5 6.1 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A HTH_8 PF02954.19 ABK71082.1 - 1.9e-12 46.8 1.8 1.9e-12 46.8 1.8 2.6 3 0 0 3 3 3 1 Bacterial regulatory protein, Fis family HTH_50 PF18024.1 ABK71082.1 - 0.00028 20.4 1.6 0.00052 19.6 0.4 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain GAF PF01590.26 ABK71082.1 - 0.0013 19.4 0.2 0.0092 16.6 0.1 2.6 2 0 0 2 2 2 1 GAF domain Sigma54_activat PF00158.26 ABK71082.1 - 0.0039 16.9 0.0 0.0087 15.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain HTH_23 PF13384.6 ABK71082.1 - 0.0048 16.7 0.1 0.018 14.8 0.1 2.1 1 0 0 1 1 1 1 Homeodomain-like domain HTH_30 PF13556.6 ABK71082.1 - 0.0052 16.6 0.2 0.11 12.3 0.1 2.6 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain AAA_16 PF13191.6 ABK71082.1 - 0.012 16.0 0.3 0.012 16.0 0.3 2.6 3 2 0 3 3 2 0 AAA ATPase domain TIP49 PF06068.13 ABK71082.1 - 0.019 14.2 0.3 0.033 13.4 0.3 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain HTH_29 PF13551.6 ABK71082.1 - 0.02 14.9 0.1 0.06 13.4 0.1 1.8 1 0 0 1 1 1 0 Winged helix-turn helix DUF134 PF02001.16 ABK71082.1 - 0.023 15.2 0.0 0.064 13.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF134 H_kinase_N PF12282.8 ABK71082.1 - 0.025 14.5 4.4 0.13 12.2 0.1 3.3 4 0 0 4 4 4 0 Signal transduction histidine kinase HTH_28 PF13518.6 ABK71082.1 - 0.025 14.7 1.0 0.17 12.0 0.2 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.7 ABK71082.1 - 0.065 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 ABK71082.1 - 0.069 12.6 0.5 0.36 10.3 0.3 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.12 ABK71082.1 - 0.097 12.6 0.1 0.25 11.3 0.1 1.6 1 0 0 1 1 1 0 HTH domain TsaE PF02367.17 ABK71082.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 ABK71082.1 - 0.18 11.3 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region HTH_38 PF13936.6 ABK71082.1 - 0.38 10.5 3.0 0.75 9.6 0.8 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Amidase PF01425.21 ABK71083.1 - 3.6e-125 418.5 2.7 4.2e-125 418.3 2.7 1.0 1 0 0 1 1 1 1 Amidase Acetyltransf_5 PF13444.6 ABK71084.1 - 1.2e-22 80.5 0.0 1.8e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Autoind_synth PF00765.17 ABK71084.1 - 0.0022 17.5 0.0 0.022 14.3 0.0 2.0 1 1 0 1 1 1 1 Autoinducer synthase PE-PPE PF08237.11 ABK71085.1 - 6.2e-51 173.1 0.2 9.9e-51 172.5 0.2 1.3 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_6 PF12697.7 ABK71085.1 - 3.1e-06 28.0 0.2 4.6e-06 27.4 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 ABK71085.1 - 0.0021 17.6 0.0 0.0046 16.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 ABK71085.1 - 0.011 15.0 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 ABK71085.1 - 0.012 15.5 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.20 ABK71085.1 - 0.087 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain FAD_binding_2 PF00890.24 ABK71086.1 - 9.8e-91 304.9 3.4 1.2e-90 304.6 3.4 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 ABK71086.1 - 2.5e-26 92.1 0.0 7.1e-26 90.7 0.0 1.7 2 0 0 2 2 2 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 ABK71086.1 - 6.6e-09 35.4 0.2 2.9e-06 26.7 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ABK71086.1 - 0.00025 20.8 7.5 0.0029 17.2 2.4 3.4 2 1 1 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ABK71086.1 - 0.00026 19.8 0.3 0.00026 19.8 0.3 2.2 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.17 ABK71086.1 - 0.0016 17.7 1.6 0.024 13.9 0.1 3.1 3 1 1 4 4 4 1 Thi4 family GIDA PF01134.22 ABK71086.1 - 0.0061 15.7 1.9 0.0061 15.7 1.9 2.5 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 ABK71086.1 - 0.043 13.1 0.4 0.11 11.7 0.4 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ABK71086.1 - 0.077 12.2 0.9 0.16 11.2 0.9 1.5 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 ABK71086.1 - 0.13 11.3 1.1 0.23 10.4 1.1 1.5 1 1 0 1 1 1 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 ABK71086.1 - 0.13 12.7 0.0 1.4 9.4 0.0 2.5 3 0 0 3 3 3 0 Putative NAD(P)-binding FAD_oxidored PF12831.7 ABK71086.1 - 0.14 11.5 4.0 0.15 11.3 2.9 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 ABK71086.1 - 0.23 10.8 1.1 0.4 9.9 1.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 ABK71086.1 - 0.28 11.5 1.8 2.2 8.6 0.4 3.0 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain TetR_C_16 PF17920.1 ABK71087.1 - 4e-33 113.9 1.9 4e-33 113.9 1.9 1.6 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK71087.1 - 2.2e-11 43.4 0.8 2.2e-11 43.4 0.8 1.6 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family FAD_binding_4 PF01565.23 ABK71088.1 - 2.6e-30 105.0 3.5 4.9e-30 104.1 2.7 1.8 1 1 1 2 2 2 1 FAD binding domain BBE PF08031.12 ABK71088.1 - 5.2e-05 23.2 0.0 0.00036 20.6 0.0 2.2 2 0 0 2 2 2 1 Berberine and berberine like Glyco_transf_28 PF03033.20 ABK71089.1 - 1.1e-08 35.2 0.0 4.3e-08 33.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 ABK71089.1 - 0.003 16.4 0.0 0.0082 15.0 0.0 1.6 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Bclx_interact PF08945.10 ABK71089.1 - 0.18 11.6 0.8 0.36 10.6 0.1 1.9 2 0 0 2 2 2 0 Bcl-x interacting, BH3 domain Glyco_trans_4_4 PF13579.6 ABK71089.1 - 2.1 8.8 13.3 1.3 9.5 6.5 3.2 2 2 0 2 2 2 0 Glycosyl transferase 4-like domain Amdase PF17645.1 ABK71090.1 - 3.3e-19 69.4 0.8 4.4e-19 69.0 0.8 1.1 1 0 0 1 1 1 1 Arylmalonate decarboxylase DUF347 PF03988.12 ABK71090.1 - 1.1 9.5 5.1 8 6.7 0.1 2.8 3 0 0 3 3 3 0 Repeat of Unknown Function (DUF347) Pirin PF02678.16 ABK71091.1 - 4.1e-30 103.9 0.1 5.9e-30 103.4 0.1 1.2 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 ABK71091.1 - 9.1e-15 54.9 0.0 1.6e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 ABK71091.1 - 0.042 13.6 0.5 0.58 9.9 0.4 2.2 2 0 0 2 2 2 0 Cupin domain ABC_tran PF00005.27 ABK71092.1 - 6.9e-35 120.5 0.0 1.2e-34 119.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 ABK71092.1 - 4.5e-12 46.0 0.3 4.5e-12 46.0 0.3 3.1 4 0 0 4 4 3 1 TOBE domain AAA_21 PF13304.6 ABK71092.1 - 2.9e-09 37.2 0.2 0.00025 20.9 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system TOBE PF03459.17 ABK71092.1 - 0.00011 22.4 0.5 0.00036 20.8 0.1 2.1 2 0 0 2 2 1 1 TOBE domain Rad17 PF03215.15 ABK71092.1 - 0.00017 21.6 0.0 0.00025 21.0 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 ABK71092.1 - 0.00018 21.9 0.0 0.0034 17.8 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TOBE_3 PF12857.7 ABK71092.1 - 0.00073 19.4 1.8 0.0016 18.3 0.0 2.4 2 1 0 2 2 2 1 TOBE-like domain SMC_N PF02463.19 ABK71092.1 - 0.0026 17.2 0.0 0.028 13.8 0.1 2.0 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ABK71092.1 - 0.0047 17.3 1.8 0.022 15.2 1.8 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 ABK71092.1 - 0.0064 16.2 1.1 0.023 14.4 1.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 ABK71092.1 - 0.0073 16.6 0.1 0.013 15.8 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ABK71092.1 - 0.0083 16.4 0.1 0.029 14.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain CysA_C_terminal PF17850.1 ABK71092.1 - 0.015 15.9 0.3 0.078 13.6 0.1 2.5 2 0 0 2 2 1 0 CysA C-terminal regulatory domain SbcCD_C PF13558.6 ABK71092.1 - 0.021 15.0 0.3 0.73 10.1 0.3 3.0 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit Mg_chelatase PF01078.21 ABK71092.1 - 0.058 12.8 0.0 0.61 9.4 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 ABK71092.1 - 0.067 12.8 0.2 0.32 10.6 0.1 2.0 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 ABK71092.1 - 0.07 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 ABK71092.1 - 0.091 13.3 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain RcpC PF16976.5 ABK71092.1 - 0.093 12.8 2.0 0.22 11.6 0.6 2.1 2 0 0 2 2 2 0 Flp pilus assembly protein RcpC/CpaB AAA_33 PF13671.6 ABK71092.1 - 0.14 12.3 0.5 0.36 11.0 0.5 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ABK71092.1 - 0.22 11.3 0.8 0.44 10.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain ADH_N PF08240.12 ABK71093.1 - 1.2e-27 95.9 4.5 1.9e-27 95.3 4.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ABK71093.1 - 6.7e-18 64.9 0.0 1.1e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ABK71093.1 - 2.2e-06 27.1 0.1 4e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ABK71093.1 - 0.00011 21.6 0.0 0.00018 20.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 ABK71093.1 - 0.00033 21.7 0.0 0.00059 20.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.6 ABK71093.1 - 0.014 15.8 0.0 0.026 15.0 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 ABK71093.1 - 0.016 15.5 0.1 0.052 13.8 0.1 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 ABK71093.1 - 0.022 14.9 0.0 0.036 14.3 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 ABK71093.1 - 0.068 13.1 0.4 0.11 12.4 0.1 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 ABK71093.1 - 0.091 12.1 1.5 4.5 6.6 2.4 2.2 1 1 1 2 2 2 0 ThiF family AMP-binding PF00501.28 ABK71094.1 - 6.4e-09 34.9 0.1 3.7e-06 25.8 0.1 2.1 2 0 0 2 2 2 2 AMP-binding enzyme PknG_TPR PF16918.5 ABK71095.1 - 6.3e-145 482.2 6.3 8.8e-145 481.7 6.3 1.2 1 0 0 1 1 1 1 Protein kinase G tetratricopeptide repeat PknG_rubred PF16919.5 ABK71095.1 - 8.5e-63 210.6 0.1 1.6e-62 209.8 0.1 1.5 1 0 0 1 1 1 1 Protein kinase G rubredoxin domain Pkinase PF00069.25 ABK71095.1 - 4.1e-33 114.9 0.0 8.1e-33 113.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ABK71095.1 - 3.1e-12 46.3 0.0 4.6e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_19 PF14559.6 ABK71095.1 - 2e-05 25.0 0.0 0.14 12.7 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat Nudix_N_2 PF14803.6 ABK71095.1 - 0.0014 18.5 2.8 0.0049 16.7 2.9 1.9 1 1 1 2 2 2 1 Nudix N-terminal DZR PF12773.7 ABK71095.1 - 0.027 14.5 0.2 0.05 13.6 0.2 1.3 1 0 0 1 1 1 0 Double zinc ribbon TPR_4 PF07721.14 ABK71095.1 - 0.044 14.4 3.3 3.1 8.7 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat RIO1 PF01163.22 ABK71095.1 - 0.082 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family zf-ribbon_3 PF13248.6 ABK71095.1 - 0.13 11.7 6.2 0.65 9.5 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain HscB_4_cys PF18256.1 ABK71095.1 - 0.55 10.1 6.3 1.9 8.4 6.3 1.9 1 1 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif zinc_ribbon_2 PF13240.6 ABK71095.1 - 2 8.3 6.8 5.8 6.8 0.4 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Fer4_15 PF13459.6 ABK71096.1 - 4.5e-17 62.5 5.9 5.5e-17 62.3 5.9 1.0 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_13 PF13370.6 ABK71096.1 - 2.2e-15 56.9 2.7 2.4e-15 56.8 2.7 1.0 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_19 PF06902.11 ABK71096.1 - 4.6e-07 29.8 1.0 5.4e-07 29.6 1.0 1.1 1 0 0 1 1 1 1 Divergent 4Fe-4S mono-cluster Fer4_2 PF12797.7 ABK71096.1 - 0.00024 21.0 0.2 0.00024 21.0 0.2 1.6 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_6 PF12837.7 ABK71096.1 - 0.0068 16.4 3.8 0.02 14.9 0.1 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_10 PF13237.6 ABK71096.1 - 0.017 15.2 1.3 0.023 14.8 1.3 1.3 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 ABK71096.1 - 0.026 15.1 0.6 0.026 15.1 0.6 1.8 2 0 0 2 2 2 0 4Fe-4S dicluster domain Me-amine-dh_L PF02975.14 ABK71096.1 - 0.038 14.5 0.2 0.038 14.5 0.2 1.0 1 0 0 1 1 1 0 Methylamine dehydrogenase, L chain DapB_N PF01113.20 ABK71097.1 - 4.6e-07 30.0 0.0 7.8e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Peripla_BP_2 PF01497.18 ABK71097.1 - 0.00031 20.4 0.0 0.00054 19.6 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein Glyoxalase PF00903.25 ABK71098.1 - 5.2e-09 36.4 0.4 1e-08 35.4 0.4 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ABK71098.1 - 8.5e-07 29.7 0.1 1.1e-06 29.4 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Peripla_BP_3 PF13377.6 ABK71099.1 - 1.9e-28 99.9 2.7 3.4e-28 99.1 2.7 1.4 1 0 0 1 1 1 1 Periplasmic binding protein-like domain LacI PF00356.21 ABK71099.1 - 3.9e-15 55.4 0.0 8.2e-15 54.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_1 PF00532.21 ABK71099.1 - 0.00068 19.1 0.1 0.00088 18.8 0.1 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family HTH_31 PF13560.6 ABK71099.1 - 0.036 14.4 4.0 0.093 13.1 1.1 2.9 2 0 0 2 2 2 0 Helix-turn-helix domain TetR_N PF00440.23 ABK71099.1 - 0.052 13.4 0.1 0.2 11.5 0.1 2.1 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family HTH_38 PF13936.6 ABK71099.1 - 0.22 11.3 2.5 5.5 6.8 0.2 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain HIT PF01230.23 ABK71100.1 - 1.2e-22 80.4 0.0 1.7e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 ABK71100.1 - 5.3e-11 43.0 0.0 7.8e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Sugar_tr PF00083.24 ABK71101.1 - 1.3e-42 146.3 25.6 2.1e-39 135.7 25.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ABK71101.1 - 3.6e-40 138.0 69.5 2.6e-35 122.0 41.7 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ABK71101.1 - 3.7e-08 32.3 27.2 1.1e-05 24.2 13.0 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein LacY_symp PF01306.19 ABK71101.1 - 0.0048 15.7 4.3 0.0048 15.7 4.3 1.8 2 0 0 2 2 2 1 LacY proton/sugar symporter DUF805 PF05656.14 ABK71101.1 - 6.6 7.2 12.2 0.22 12.0 0.4 3.5 2 2 1 3 3 3 0 Protein of unknown function (DUF805) SnoaL_2 PF12680.7 ABK71102.1 - 4.9e-12 46.4 0.2 6.2e-12 46.1 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 ABK71102.1 - 2.2e-05 24.8 0.0 3.1e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) PrmC_N PF17827.1 ABK71103.1 - 7e-18 65.0 0.9 1.2e-17 64.3 0.2 1.8 2 0 0 2 2 1 1 PrmC N-terminal domain MTS PF05175.14 ABK71103.1 - 4.4e-15 55.6 0.0 2.5e-14 53.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 ABK71103.1 - 5.1e-11 43.1 0.1 2.1e-10 41.2 0.0 2.0 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABK71103.1 - 8.8e-10 38.6 0.0 1.3e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABK71103.1 - 1.3e-07 32.1 0.1 2.3e-06 28.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 ABK71103.1 - 2.6e-05 24.0 0.0 0.00014 21.6 0.0 1.9 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_4 PF02390.17 ABK71103.1 - 7.1e-05 22.3 0.0 0.0003 20.3 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase Met_10 PF02475.16 ABK71103.1 - 9.5e-05 22.2 0.0 0.00014 21.7 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.13 ABK71103.1 - 0.00012 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 ABK71103.1 - 0.00023 21.3 0.0 0.00037 20.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase UPF0020 PF01170.18 ABK71103.1 - 0.0003 20.5 0.0 0.00063 19.5 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.7 ABK71103.1 - 0.0026 17.7 0.0 0.0039 17.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 ABK71103.1 - 0.0095 15.0 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_23 PF13489.6 ABK71103.1 - 0.012 15.4 0.0 0.019 14.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 ABK71103.1 - 0.015 16.1 0.0 0.049 14.4 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 ABK71103.1 - 0.03 15.3 0.2 0.41 11.7 0.0 2.5 3 0 0 3 3 3 0 Methyltransferase domain PALP PF00291.25 ABK71103.1 - 0.031 13.7 0.2 0.063 12.7 0.2 1.7 1 1 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Methyltransf_19 PF04672.12 ABK71103.1 - 0.048 13.1 0.2 0.18 11.2 0.1 1.9 2 0 0 2 2 2 0 S-adenosyl methyltransferase Ubie_methyltran PF01209.18 ABK71103.1 - 0.073 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 ABK71103.1 - 0.19 11.5 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase CT_A_B PF02626.15 ABK71104.1 - 6.3e-91 304.7 0.1 8.4e-91 304.2 0.1 1.2 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CT_C_D PF02682.16 ABK71104.1 - 2.6e-49 167.7 0.0 4.1e-49 167.1 0.0 1.3 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D PspA_IM30 PF04012.12 ABK71106.1 - 1.2e-56 191.8 33.8 1.4e-56 191.6 33.8 1.0 1 0 0 1 1 1 1 PspA/IM30 family Bep_C_terminal PF17841.1 ABK71106.1 - 0.19 12.0 14.8 0.09 13.0 5.0 3.2 2 1 0 3 3 3 0 BID domain of Bartonella effector protein (Bep) LUC7 PF03194.15 ABK71106.1 - 1.2 8.7 22.4 1.1e+02 2.3 22.4 2.2 1 1 0 1 1 1 0 LUC7 N_terminus DUF948 PF06103.11 ABK71106.1 - 3.2 8.1 11.7 0.16 12.3 2.1 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Tweety PF04906.13 ABK71106.1 - 5.4 5.6 12.4 0.59 8.7 3.2 2.1 1 1 1 2 2 2 0 Tweety DUF883 PF05957.13 ABK71106.1 - 7.6 7.2 20.3 0.19 12.4 0.5 3.6 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF883) AAA_13 PF13166.6 ABK71106.1 - 8.5 4.9 17.0 0.12 11.0 2.1 2.3 1 1 0 2 2 2 0 AAA domain DAHP_synth_2 PF01474.16 ABK71107.1 - 4.4e-188 625.2 0.0 5e-188 625.1 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Lipase_GDSL_2 PF13472.6 ABK71108.1 - 8e-25 88.3 0.2 1e-24 87.9 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ABK71108.1 - 3.6e-13 49.9 0.0 5e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase OSK PF17182.4 ABK71108.1 - 0.00031 20.0 0.0 0.0004 19.7 0.0 1.1 1 0 0 1 1 1 1 OSK domain Na_Ca_ex PF01699.24 ABK71109.1 - 1.4e-20 73.7 41.3 1.3e-14 54.5 15.3 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein GRP PF07172.11 ABK71109.1 - 0.0077 16.9 0.8 0.015 16.0 0.2 1.8 1 1 0 1 1 1 1 Glycine rich protein family DUF4307 PF14155.6 ABK71109.1 - 0.32 10.8 10.4 1.2 9.0 0.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4307) YukD PF08817.10 ABK71110.1 - 5.6e-19 68.6 1.3 8.6e-19 68.0 0.2 1.9 2 0 0 2 2 2 1 WXG100 protein secretion system (Wss), protein YukD TetR_C_33 PF13305.6 ABK71111.1 - 2.9e-13 50.5 1.8 6.8e-13 49.3 1.8 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK71111.1 - 1.6e-11 43.8 0.0 3.3e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_38 PF13936.6 ABK71111.1 - 0.0039 16.9 0.0 0.041 13.7 0.0 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain FGGY_N PF00370.21 ABK71112.1 - 7.1e-42 143.7 0.0 1.1e-41 143.0 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 ABK71112.1 - 1.7e-23 83.4 0.1 4.1e-23 82.2 0.1 1.7 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain HSP70 PF00012.20 ABK71112.1 - 0.013 13.7 0.0 0.022 13.0 0.0 1.2 1 0 0 1 1 1 0 Hsp70 protein Aminotran_MocR PF12897.7 ABK71113.1 - 3.9e-188 625.5 0.0 4.4e-188 625.3 0.0 1.0 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Aminotran_1_2 PF00155.21 ABK71113.1 - 5.9e-11 42.1 0.0 9e-11 41.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Acyl-CoA_dh_1 PF00441.24 ABK71114.1 - 4e-42 144.0 2.9 6.4e-42 143.3 2.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK71114.1 - 1.7e-28 99.5 0.4 5.4e-28 97.9 0.2 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ABK71114.1 - 8.9e-26 89.9 0.2 1.6e-25 89.1 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ABK71114.1 - 5.2e-22 78.6 3.8 8.6e-22 77.8 3.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain zf-HC2 PF13490.6 ABK71114.1 - 0.086 13.1 0.1 0.24 11.7 0.1 1.9 1 0 0 1 1 1 0 Putative zinc-finger DUF922 PF06037.11 ABK71114.1 - 0.18 11.6 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF922) Mg_chelatase PF01078.21 ABK71115.1 - 4.5e-83 277.7 0.0 6.6e-83 277.2 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ChlI PF13541.6 ABK71115.1 - 3e-38 130.4 0.0 4.4e-38 129.8 0.0 1.3 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Mg_chelatase_C PF13335.6 ABK71115.1 - 3e-24 85.4 1.0 7.1e-24 84.3 1.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI C-terminal AAA_5 PF07728.14 ABK71115.1 - 2.5e-09 37.3 0.0 0.00049 20.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 ABK71115.1 - 9.8e-08 31.9 0.0 0.0043 16.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain MCM PF00493.23 ABK71115.1 - 1.8e-07 30.5 0.0 2.6e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 MCM P-loop domain Lon_C PF05362.13 ABK71115.1 - 9.5e-07 28.6 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA_22 PF13401.6 ABK71115.1 - 2.4e-06 27.9 0.0 0.00024 21.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ABK71115.1 - 4.5e-05 23.2 0.1 9.6e-05 22.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 ABK71115.1 - 9.8e-05 22.2 0.1 0.023 14.5 0.0 2.6 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 ABK71115.1 - 0.00013 22.4 0.0 0.00077 19.9 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ABK71115.1 - 0.00039 20.8 0.2 0.0051 17.2 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_7 PF12775.7 ABK71115.1 - 0.0092 15.5 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_lid_2 PF17863.1 ABK71115.1 - 0.01 15.7 0.3 0.037 13.8 0.3 2.0 1 0 0 1 1 1 0 AAA lid domain AAA_19 PF13245.6 ABK71115.1 - 0.013 15.8 0.2 0.043 14.2 0.2 2.0 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 ABK71115.1 - 0.015 15.4 0.0 1.4 9.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.6 ABK71115.1 - 0.024 15.2 0.0 0.059 13.9 0.0 1.6 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 ABK71115.1 - 0.026 14.5 0.0 0.072 13.0 0.0 1.8 2 0 0 2 2 1 0 NACHT domain AAA_33 PF13671.6 ABK71115.1 - 0.05 13.8 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 ABK71115.1 - 0.071 12.9 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ABK71115.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 ABK71115.1 - 0.12 11.5 0.1 0.31 10.2 0.0 1.6 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_28 PF13521.6 ABK71115.1 - 0.15 12.3 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 ABK71115.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_32 PF13654.6 ABK71115.1 - 0.22 10.3 0.0 0.99 8.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 ABK71117.1 - 6.4e-51 172.7 0.0 9.6e-51 172.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 ABK71117.1 - 5.4e-48 161.6 1.3 9.4e-48 160.8 0.7 1.7 2 0 0 2 2 2 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 ABK71117.1 - 2.2e-21 75.7 0.0 4.8e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ABK71117.1 - 8.5e-05 22.9 2.9 0.00021 21.6 2.9 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ABK71117.1 - 0.00017 21.6 0.0 0.00031 20.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 ABK71117.1 - 0.0007 19.6 0.0 0.0033 17.5 0.0 2.1 1 1 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 ABK71117.1 - 0.18 11.7 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain PadR PF03551.14 ABK71118.1 - 1e-21 76.6 0.0 2e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family FUR PF01475.19 ABK71118.1 - 0.00095 19.3 0.0 0.0018 18.4 0.0 1.4 1 0 0 1 1 1 1 Ferric uptake regulator family DUF1495 PF07381.11 ABK71118.1 - 0.0028 17.4 0.0 0.037 13.8 0.0 2.5 2 1 0 2 2 2 1 Winged helix DNA-binding domain (DUF1495) AphA_like PF14557.6 ABK71118.1 - 0.0041 16.9 0.4 0.0089 15.8 0.0 1.8 2 0 0 2 2 2 1 Putative AphA-like transcriptional regulator DUF4364 PF14277.6 ABK71118.1 - 0.011 15.5 0.0 0.029 14.1 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4364) RTP PF02334.16 ABK71118.1 - 0.039 14.6 0.0 0.075 13.7 0.0 1.4 1 0 0 1 1 1 0 Replication terminator protein Glyco_hydro_130 PF04041.13 ABK71119.1 - 5.5e-30 104.4 0.0 8e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 beta-1,4-mannooligosaccharide phosphorylase MDMPI_N PF11716.8 ABK71120.1 - 2.4e-20 73.7 12.6 2.4e-20 73.7 12.6 2.3 2 1 0 2 2 2 1 Mycothiol maleylpyruvate isomerase N-terminal domain MDMPI_C PF07398.11 ABK71120.1 - 3e-12 47.2 11.6 3e-12 47.2 11.6 2.1 2 1 0 2 2 2 1 MDMPI C-terminal domain DinB_2 PF12867.7 ABK71120.1 - 1.2e-05 25.8 1.1 2.9e-05 24.6 1.1 1.6 1 0 0 1 1 1 1 DinB superfamily DinB PF05163.12 ABK71120.1 - 6.1e-05 23.0 0.1 8.8e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 DinB family PMI_typeI PF01238.21 ABK71121.1 - 6.3e-56 190.2 0.0 2.7e-55 188.1 0.0 1.8 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 ABK71121.1 - 0.00031 20.4 0.0 0.72 9.6 0.0 2.7 3 0 0 3 3 3 2 Cupin domain AraC_binding PF02311.19 ABK71121.1 - 0.0045 16.9 0.8 0.2 11.6 0.0 2.7 3 0 0 3 3 3 1 AraC-like ligand binding domain DUF2156 PF09924.9 ABK71122.1 - 3.5e-101 338.1 0.1 5e-101 337.6 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA-synt_2_TM PF16995.5 ABK71122.1 - 1.9e-82 276.2 23.8 2.8e-82 275.6 23.8 1.3 1 0 0 1 1 1 1 Transmembrane region of lysyl-tRNA synthetase tRNA-synt_2 PF00152.20 ABK71122.1 - 1.2e-65 221.7 0.0 1.7e-65 221.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ABK71122.1 - 7.1e-13 48.3 0.0 1.5e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 ABK71122.1 - 9e-05 22.1 0.0 0.0068 15.9 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) PknH_C PF14032.6 ABK71123.1 - 5.7e-38 130.7 4.8 6.7e-38 130.4 4.8 1.1 1 0 0 1 1 1 1 PknH-like extracellular domain TetR_N PF00440.23 ABK71124.1 - 5.3e-19 67.7 1.9 1.1e-18 66.7 1.3 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 ABK71124.1 - 3.1e-05 24.2 0.9 3.1e-05 24.2 0.9 2.6 2 1 1 3 3 3 1 BetI-type transcriptional repressor, C-terminal TetR_C_31 PF17940.1 ABK71124.1 - 0.044 14.0 0.5 0.044 14.0 0.5 2.6 1 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HxlR PF01638.17 ABK71125.1 - 5.3e-20 71.1 0.0 6.8e-20 70.7 0.0 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix PadR PF03551.14 ABK71125.1 - 0.0056 16.6 0.0 0.0093 15.9 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family Replic_Relax PF13814.6 ABK71125.1 - 0.045 13.8 0.0 0.059 13.4 0.0 1.2 1 0 0 1 1 1 0 Replication-relaxation adh_short_C2 PF13561.6 ABK71126.1 - 4.7e-59 199.8 0.1 6e-59 199.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK71126.1 - 2.3e-56 190.4 0.0 2.7e-56 190.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK71126.1 - 1.3e-20 74.0 0.4 1.8e-20 73.6 0.4 1.1 1 0 0 1 1 1 1 KR domain Ni_hydr_CYTB PF01292.20 ABK71128.1 - 1e-19 70.8 18.0 1.3e-19 70.5 18.0 1.1 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 Transthyretin PF00576.21 ABK71129.1 - 3.5e-31 108.2 0.0 3.9e-31 108.0 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family bMG3 PF11974.8 ABK71129.1 - 8.6e-06 25.7 0.1 1.6e-05 24.9 0.1 1.3 1 1 0 1 1 1 1 Bacterial alpha-2-macroglobulin MG3 domain CarboxypepD_reg PF13620.6 ABK71129.1 - 0.00044 20.5 2.0 0.0006 20.0 2.0 1.3 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain Big_1 PF02369.16 ABK71129.1 - 0.00075 19.5 0.1 0.0011 18.9 0.1 1.3 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 1) Big_6 PF17936.1 ABK71129.1 - 0.029 14.6 0.3 0.047 14.0 0.3 1.3 1 0 0 1 1 1 0 Bacterial Ig domain SdrD_B PF17210.3 ABK71129.1 - 0.12 12.7 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 SdrD B-like domain Acyl-CoA_dh_1 PF00441.24 ABK71130.1 - 1.5e-44 151.8 7.8 2.4e-44 151.2 7.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 ABK71130.1 - 1.1e-19 71.0 5.8 2.1e-19 70.1 5.8 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK71130.1 - 2e-15 57.4 0.1 7.1e-15 55.7 0.1 2.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ABK71130.1 - 1.8e-13 50.5 0.0 3.7e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Abhydrolase_1 PF00561.20 ABK71131.1 - 4.2e-28 98.7 0.0 1.2e-26 93.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK71131.1 - 6.8e-23 82.4 2.3 8.1e-23 82.2 2.3 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK71131.1 - 4.2e-18 65.5 0.1 1.2e-17 64.0 0.1 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 ABK71131.1 - 0.00059 19.4 0.0 0.0029 17.1 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 ABK71131.1 - 0.001 19.2 0.3 0.0034 17.5 0.0 2.0 3 0 0 3 3 3 1 TAP-like protein FSH1 PF03959.13 ABK71131.1 - 0.0015 18.3 0.0 0.012 15.2 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DUF4376 PF14301.6 ABK71131.1 - 0.017 15.5 0.0 0.041 14.2 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4376) CHASE2 PF05226.11 ABK71131.1 - 0.099 12.3 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 CHASE2 domain Ser_hydrolase PF06821.13 ABK71131.1 - 0.12 12.2 0.1 1.8 8.4 0.0 2.3 2 0 0 2 2 2 0 Serine hydrolase CPSase_L_D2 PF02786.17 ABK71132.1 - 6.9e-80 267.5 0.0 1.3e-79 266.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ABK71132.1 - 1.2e-43 148.1 1.7 2.5e-43 147.1 0.7 2.0 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ABK71132.1 - 3.1e-34 117.3 0.0 1.5e-33 115.2 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 ABK71132.1 - 6.6e-15 54.7 3.7 1.6e-14 53.5 3.7 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 ABK71132.1 - 1.9e-10 40.6 0.0 4.1e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 ABK71132.1 - 4.7e-07 29.5 0.0 7.7e-06 25.6 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 ABK71132.1 - 1.4e-06 28.0 3.2 0.003 17.3 0.7 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like PCC_BT PF18140.1 ABK71132.1 - 0.0086 16.4 0.6 0.12 12.7 0.0 2.5 2 0 0 2 2 2 1 Propionyl-coenzyme A carboxylase BT domain Peptidase_M23 PF01551.22 ABK71132.1 - 0.0093 16.2 0.6 0.039 14.2 0.4 2.3 2 0 0 2 2 2 1 Peptidase family M23 ATP-grasp_3 PF02655.14 ABK71132.1 - 0.013 15.6 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain RnfC_N PF13375.6 ABK71132.1 - 0.02 14.8 0.9 0.14 12.2 0.3 2.6 2 1 0 2 2 2 0 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 ABK71132.1 - 0.075 12.2 0.6 8.2 5.6 0.0 2.7 2 1 1 3 3 3 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 ABK71132.1 - 2.7 8.7 7.1 1.9 9.3 0.2 3.2 3 0 0 3 3 3 0 HlyD family secretion protein PSK_trans_fac PF07704.11 ABK71133.1 - 4.6e-28 97.8 2.8 5.1e-28 97.7 2.8 1.0 1 0 0 1 1 1 1 Rv0623-like transcription factor Cep57_CLD_2 PF14197.6 ABK71133.1 - 0.1 12.7 0.3 2.4 8.3 0.3 2.5 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 MatP_C PF17414.2 ABK71133.1 - 0.14 12.4 0.0 0.2 11.9 0.0 1.1 1 0 0 1 1 1 0 MatP C-terminal ribbon-helix-helix domain Arabinose_trans PF04602.12 ABK71134.1 - 5.9e-175 582.5 37.8 8.1e-175 582.1 37.8 1.2 1 0 0 1 1 1 1 Mycobacterial cell wall arabinan synthesis protein Arabino_trans_C PF14896.6 ABK71134.1 - 3.3e-147 490.5 0.2 4.2e-147 490.2 0.2 1.1 1 0 0 1 1 1 1 EmbC C-terminal domain Arabino_trans_N PF17689.1 ABK71134.1 - 3.4e-50 170.3 0.2 6e-50 169.5 0.2 1.4 1 0 0 1 1 1 1 Arabinosyltransferase concanavalin like domain CDO_I PF05995.12 ABK71135.1 - 2.6e-14 52.9 3.3 3e-13 49.4 3.3 2.0 1 1 0 1 1 1 1 Cysteine dioxygenase type I Cupin_2 PF07883.11 ABK71135.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Cupin domain AA_permease_2 PF13520.6 ABK71136.1 - 1.3e-46 159.3 54.8 1.5e-46 159.1 54.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ABK71136.1 - 2e-27 96.0 43.3 2.7e-27 95.5 43.3 1.2 1 0 0 1 1 1 1 Amino acid permease Ndc1_Nup PF09531.10 ABK71136.1 - 3.4 6.3 5.2 11 4.5 5.6 1.7 1 1 0 1 1 1 0 Nucleoporin protein Ndc1-Nup IclR PF01614.18 ABK71137.1 - 2.4e-29 101.8 0.0 3.5e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 ABK71137.1 - 1e-13 50.8 1.9 1e-13 50.8 1.9 1.9 2 0 0 2 2 2 1 IclR helix-turn-helix domain MarR_2 PF12802.7 ABK71137.1 - 6e-05 22.8 1.1 0.00015 21.5 1.1 1.7 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 ABK71137.1 - 0.0053 17.1 0.0 0.041 14.2 0.0 2.4 2 1 0 2 2 2 1 Transcriptional regulator HTH_24 PF13412.6 ABK71137.1 - 0.0088 15.6 0.6 0.021 14.4 0.1 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 ABK71137.1 - 0.021 14.9 1.4 0.056 13.5 0.5 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain MarR PF01047.22 ABK71137.1 - 0.053 13.5 0.1 0.096 12.6 0.1 1.4 1 0 0 1 1 1 0 MarR family HTH_27 PF13463.6 ABK71137.1 - 0.11 13.0 0.2 0.32 11.5 0.1 1.8 2 0 0 2 2 2 0 Winged helix DNA-binding domain Sigma70_r4 PF04545.16 ABK71137.1 - 0.12 11.9 1.2 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 TrmB PF01978.19 ABK71137.1 - 0.16 11.8 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Peptidase_M23 PF01551.22 ABK71138.1 - 2.1e-16 59.9 0.0 6e-16 58.4 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M23 LPAM_1 PF08139.12 ABK71138.1 - 1.7 9.3 3.6 4.7 7.9 3.6 1.8 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site ArsA_ATPase PF02374.15 ABK71139.1 - 4.5e-27 95.0 0.0 7.5e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 ABK71139.1 - 5.6e-11 42.7 0.0 9.4e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 ABK71139.1 - 1.3e-08 34.9 0.0 7.7e-08 32.4 0.0 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 ABK71139.1 - 4e-07 29.8 0.6 1.4e-05 24.7 0.0 2.3 1 1 1 2 2 2 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 ABK71139.1 - 0.00022 20.9 0.4 0.0007 19.3 0.1 1.9 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain PhoH PF02562.16 ABK71139.1 - 0.00063 19.3 0.1 0.00095 18.7 0.1 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA_30 PF13604.6 ABK71139.1 - 0.0011 18.8 2.1 0.0024 17.6 2.1 1.7 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 ABK71139.1 - 0.0017 17.4 0.9 0.004 16.2 0.3 1.9 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB IstB_IS21 PF01695.17 ABK71139.1 - 0.0019 18.0 0.1 0.0038 17.0 0.1 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 ABK71139.1 - 0.0033 17.7 0.1 0.01 16.1 0.1 1.9 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 ABK71139.1 - 0.0045 16.8 0.2 0.023 14.5 0.1 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 ABK71139.1 - 0.006 17.0 0.3 0.064 13.6 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_26 PF13500.6 ABK71139.1 - 0.0072 16.2 0.0 0.18 11.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain CobA_CobO_BtuR PF02572.15 ABK71139.1 - 0.0093 16.2 5.2 0.023 15.0 0.6 2.9 3 0 0 3 3 3 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP AAA_33 PF13671.6 ABK71139.1 - 0.0098 16.1 0.1 0.027 14.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 ABK71139.1 - 0.013 15.0 0.1 0.029 13.8 0.1 1.6 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family TrkA_N PF02254.18 ABK71139.1 - 0.014 15.7 0.1 25 5.1 0.0 3.5 3 0 0 3 3 3 0 TrkA-N domain YjeF_N PF03853.15 ABK71139.1 - 0.014 15.2 0.2 0.069 13.0 0.3 2.0 2 0 0 2 2 2 0 YjeF-related protein N-terminus MipZ PF09140.11 ABK71139.1 - 0.028 13.7 0.6 0.68 9.2 0.2 2.2 2 0 0 2 2 2 0 ATPase MipZ Methyltransf_24 PF13578.6 ABK71139.1 - 0.031 15.3 0.4 0.22 12.6 0.0 2.4 2 2 0 2 2 2 0 Methyltransferase domain AdoHcyase_NAD PF00670.21 ABK71139.1 - 0.072 13.2 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ATPase PF06745.13 ABK71139.1 - 0.094 12.0 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.6 ABK71139.1 - 0.11 12.1 4.5 0.93 9.0 4.5 2.3 1 1 0 1 1 1 0 AAA domain KdpD PF02702.17 ABK71139.1 - 0.13 11.7 0.1 0.47 9.9 0.0 1.9 2 0 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain Polysacc_synt_4 PF04669.13 ABK71139.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis AAA_24 PF13479.6 ABK71139.1 - 0.19 11.4 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ABK71139.1 - 0.41 10.9 4.2 0.2 11.9 0.6 2.4 3 1 0 3 3 3 0 AAA domain Ferritin PF00210.24 ABK71142.1 - 2.5e-35 121.5 0.6 3e-35 121.2 0.6 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 ABK71142.1 - 5.6e-06 26.8 0.0 1.2e-05 25.8 0.0 1.5 1 1 0 1 1 1 1 Rubrerythrin kleA_kleC PF17383.2 ABK71142.1 - 0.042 14.2 0.1 0.15 12.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A PAS_4 PF08448.10 ABK71143.1 - 5.1e-11 42.8 0.3 5.1e-11 42.8 0.3 2.0 2 0 0 2 2 2 1 PAS fold HisKA_3 PF07730.13 ABK71143.1 - 2.6e-10 40.7 7.7 2.6e-10 40.7 7.7 2.3 2 0 0 2 2 2 1 Histidine kinase HATPase_c PF02518.26 ABK71143.1 - 1.4e-09 38.4 0.7 1.4e-07 32.0 0.7 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 ABK71143.1 - 3.4e-09 36.9 0.0 6.3e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 ABK71143.1 - 3.2e-08 33.6 0.0 1e-07 31.9 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 ABK71143.1 - 6.1e-07 29.3 0.0 1.4e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_7 PF12860.7 ABK71143.1 - 8.6e-05 22.7 0.0 0.00043 20.4 0.0 2.2 2 1 0 2 2 2 1 PAS fold HATPase_c_2 PF13581.6 ABK71143.1 - 0.0001 22.3 0.8 0.00036 20.5 0.6 2.0 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain Nup54 PF13874.6 ABK71143.1 - 0.17 12.0 3.3 0.31 11.1 3.3 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 ABC_tran PF00005.27 ABK71144.1 - 9e-31 107.2 0.0 1.3e-30 106.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK71144.1 - 3.2e-08 33.7 0.3 0.0043 16.9 0.1 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK71144.1 - 7.2e-06 25.6 0.0 0.0027 17.2 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 ABK71144.1 - 0.0012 19.2 1.6 0.0067 16.7 0.1 2.3 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ABK71144.1 - 0.002 18.1 0.0 0.0043 17.0 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 ABK71144.1 - 0.003 18.0 4.4 0.03 14.7 4.3 2.1 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 ABK71144.1 - 0.0042 17.1 0.0 0.0068 16.5 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 ABK71144.1 - 0.0043 17.3 0.5 0.015 15.6 0.5 2.0 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 ABK71144.1 - 0.0045 15.8 0.1 0.061 12.1 0.0 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_33 PF13671.6 ABK71144.1 - 0.0053 16.9 0.7 0.019 15.1 0.7 1.9 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ABK71144.1 - 0.007 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 ABK71144.1 - 0.0073 15.9 0.2 0.036 13.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ABK71144.1 - 0.036 14.0 0.0 0.083 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 ABK71144.1 - 0.038 13.7 0.2 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ABK71144.1 - 0.041 13.8 0.4 0.086 12.7 0.1 1.6 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 ABK71144.1 - 0.041 14.4 0.0 0.059 13.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 ABK71144.1 - 0.074 12.8 0.0 0.096 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 ABK71144.1 - 0.078 12.9 0.0 0.55 10.1 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 ABK71144.1 - 0.08 12.2 0.2 0.16 11.2 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.22 ABK71144.1 - 0.13 11.4 0.0 0.26 10.4 0.0 1.4 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.29 ABK71144.1 - 0.19 12.1 0.3 0.94 9.9 0.1 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 ABK71144.1 - 0.21 11.3 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SbcCD_C PF13558.6 ABK71144.1 - 0.21 11.9 0.9 3.4 8.0 0.9 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 ABK71144.1 - 0.26 11.7 0.0 0.42 11.0 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 ABK71144.1 - 0.85 10.2 4.2 1.1 9.8 0.4 2.3 2 0 0 2 2 2 0 AAA domain FA_hydroxylase PF04116.13 ABK71145.1 - 5.7e-15 55.8 4.0 7.9e-15 55.4 4.0 1.2 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily TetR_N PF00440.23 ABK71147.1 - 4.5e-12 45.6 0.1 9.3e-12 44.6 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family Aminotran_3 PF00202.21 ABK71148.1 - 2.2e-117 392.2 0.0 2.6e-117 391.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III GT87 PF09594.10 ABK71149.1 - 1.3e-58 198.6 36.4 1.3e-58 198.6 36.4 3.5 3 1 0 3 3 3 2 Glycosyltransferase family 87 MFS_3 PF05977.13 ABK71151.1 - 8.7e-153 509.4 33.1 1e-152 509.2 33.1 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.16 ABK71151.1 - 1.2e-27 96.7 82.2 5.5e-24 84.8 43.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 ABK71152.1 - 3.7e-70 237.0 0.0 4.9e-70 236.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABC2_membrane PF01061.24 ABK71153.1 - 2.4e-37 128.4 13.4 3.4e-37 127.9 13.4 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 ABK71153.1 - 9e-14 51.3 14.5 1.2e-13 51.0 14.5 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_6 PF06182.11 ABK71153.1 - 0.021 14.6 5.8 0.029 14.1 5.8 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 ABK71153.1 - 0.075 13.0 7.0 0.024 14.6 3.4 1.9 2 0 0 2 2 2 0 ABC-2 family transporter protein GvpL_GvpF PF06386.11 ABK71154.1 - 8.8e-54 183.0 4.5 1.1e-53 182.7 4.5 1.0 1 0 0 1 1 1 1 Gas vesicle synthesis protein GvpL/GvpF Acyl-CoA_dh_1 PF00441.24 ABK71155.1 - 2.3e-40 138.2 5.4 8.7e-22 78.0 4.4 2.4 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK71155.1 - 7.1e-26 91.1 0.0 1.3e-12 48.4 0.0 2.7 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ABK71155.1 - 2.2e-21 75.8 0.0 5.9e-19 68.1 0.0 2.5 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ABK71155.1 - 2.8e-06 27.6 6.2 6.5e-06 26.4 6.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Lactamase_B_3 PF13483.6 ABK71156.1 - 1.6e-21 76.9 0.1 2.2e-21 76.4 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 ABK71156.1 - 9.5e-09 35.1 1.7 2.9e-08 33.5 1.7 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ABK71156.1 - 0.0031 17.5 8.5 0.056 13.4 8.5 2.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily FliC_SP PF12613.8 ABK71156.1 - 0.33 11.5 5.8 0.71 10.4 5.8 1.5 1 0 0 1 1 1 0 Flagellin structural protein MFS_1 PF07690.16 ABK71157.1 - 9.8e-41 139.8 68.3 2.5e-35 122.1 41.2 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK71157.1 - 2e-36 125.9 25.9 1e-22 80.7 8.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 ABK71157.1 - 9.1e-10 37.7 19.0 9.4e-07 27.7 7.0 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein LacY_symp PF01306.19 ABK71157.1 - 0.0013 17.6 6.2 0.0013 17.6 6.2 2.0 2 0 0 2 2 2 1 LacY proton/sugar symporter DUF3558 PF12079.8 ABK71158.1 - 5e-08 33.1 0.1 6.4e-08 32.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3558) CoA_transf_3 PF02515.17 ABK71159.1 - 1.8e-92 310.3 2.3 2e-92 310.1 2.3 1.0 1 0 0 1 1 1 1 CoA-transferase family III SpoU_methylase PF00588.19 ABK71160.1 - 3.8e-33 114.7 0.0 5e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 ABK71160.1 - 9.9e-07 28.9 0.0 1.6e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding LacAB_rpiB PF02502.18 ABK71161.1 - 1e-45 155.1 0.0 1.2e-45 154.9 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Ribosomal_S18 PF01084.20 ABK71162.1 - 1.6e-24 85.8 0.1 2.8e-24 85.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 DUF3826 PF12875.7 ABK71162.1 - 0.11 12.6 0.3 0.14 12.2 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3826) rve PF00665.26 ABK71163.1 - 5.9e-26 91.0 0.0 8.9e-26 90.4 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 ABK71163.1 - 7e-07 28.9 0.0 3.8e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain rve_2 PF13333.6 ABK71163.1 - 0.00063 19.9 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain WXG100 PF06013.12 ABK71164.1 - 0.00014 22.0 5.3 0.00014 22.0 5.3 1.6 2 0 0 2 2 2 1 Proteins of 100 residues with WXG PsbN PF02468.15 ABK71164.1 - 0.21 11.4 1.8 1.4 8.8 1.1 2.2 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) HTH_18 PF12833.7 ABK71165.1 - 1.2e-16 60.7 0.0 2e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 ABK71165.1 - 0.0038 17.3 0.0 0.12 12.5 0.0 2.4 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family Pribosyltran PF00156.27 ABK71166.1 - 1.1e-15 57.5 0.7 1.4e-15 57.2 0.7 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 ABK71166.1 - 0.002 17.6 0.0 0.003 17.0 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase ATP-grasp_5 PF13549.6 ABK71166.1 - 0.052 13.0 0.0 0.069 12.6 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain CPT PF07931.12 ABK71166.1 - 0.092 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Pribosyl_synth PF14572.6 ABK71166.1 - 0.18 11.8 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain AMP-binding PF00501.28 ABK71167.1 - 8.4e-76 255.2 0.0 1e-75 255.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C_2 PF14535.6 ABK71167.1 - 0.01 16.1 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 ABK71168.1 - 2.8e-30 105.3 0.1 4.3e-30 104.7 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK71168.1 - 4e-20 72.6 2.3 9.4e-20 71.4 2.3 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acyl_transf_3 PF01757.22 ABK71169.1 - 3e-22 79.1 34.9 3.7e-22 78.9 34.9 1.0 1 0 0 1 1 1 1 Acyltransferase family MlaD PF02470.20 ABK71170.1 - 1.6e-15 57.2 0.4 6.7e-15 55.2 0.1 2.1 2 0 0 2 2 2 1 MlaD protein Mce4_CUP1 PF11887.8 ABK71170.1 - 7.2e-06 25.6 1.4 9.9e-06 25.2 1.4 1.1 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative SIKE PF05769.11 ABK71170.1 - 0.013 15.4 0.1 0.021 14.8 0.1 1.2 1 0 0 1 1 1 0 SIKE family FlgN PF05130.12 ABK71170.1 - 0.079 13.5 0.1 0.13 12.8 0.1 1.4 1 0 0 1 1 1 0 FlgN protein Mer2 PF09074.10 ABK71170.1 - 0.1 12.4 0.1 0.14 11.9 0.1 1.1 1 0 0 1 1 1 0 Mer2 Hemagglutinin PF00509.18 ABK71170.1 - 0.28 9.5 0.1 0.38 9.1 0.1 1.1 1 0 0 1 1 1 0 Haemagglutinin Trp_syntA PF00290.20 ABK71171.1 - 9.7e-70 234.4 0.0 1.1e-69 234.1 0.0 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain His_biosynth PF00977.21 ABK71171.1 - 0.0021 17.6 0.1 0.004 16.7 0.1 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein PcrB PF01884.17 ABK71171.1 - 0.0064 16.0 0.1 0.011 15.2 0.1 1.3 1 0 0 1 1 1 1 PcrB family BtpA PF03437.15 ABK71171.1 - 0.013 15.0 0.4 0.032 13.7 0.1 1.8 2 0 0 2 2 2 0 BtpA family Radical_SAM PF04055.21 ABK71172.1 - 2.7e-10 40.9 0.0 4.1e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 ABK71172.1 - 0.019 15.2 0.0 0.031 14.5 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain Bact_transglu_N PF08379.10 ABK71173.1 - 1.5e-20 73.8 0.4 3.1e-20 72.8 0.4 1.6 1 0 0 1 1 1 1 Bacterial transglutaminase-like N-terminal region Transglut_core PF01841.19 ABK71173.1 - 3.5e-18 66.1 0.0 6e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.12 ABK71173.1 - 0.0013 18.3 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like domain CoA_transf_3 PF02515.17 ABK71174.1 - 7.1e-120 400.5 0.0 8.1e-120 400.3 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Lpp-LpqN PF10738.9 ABK71176.1 - 3.9e-55 186.0 0.0 7.8e-55 185.0 0.0 1.5 1 0 0 1 1 1 1 Probable lipoprotein LpqN Pkinase PF00069.25 ABK71176.1 - 4.5e-40 137.7 0.0 5.9e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ABK71176.1 - 1.6e-25 89.9 0.0 2.1e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ABK71176.1 - 0.00011 21.1 0.0 0.00017 20.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ABK71176.1 - 0.00061 19.8 1.6 0.061 13.2 0.1 2.8 3 1 1 4 4 4 2 Phosphotransferase enzyme family Kdo PF06293.14 ABK71176.1 - 0.0009 18.7 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3185 PF11381.8 ABK71176.1 - 0.005 16.8 0.3 0.012 15.6 0.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3185) Abhydrolase_3 PF07859.13 ABK71177.1 - 0.00061 19.7 0.1 0.0011 18.9 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK71177.1 - 0.011 16.4 6.0 0.011 16.4 6.0 2.6 1 1 1 2 2 2 0 Alpha/beta hydrolase family UPF0227 PF05728.12 ABK71177.1 - 0.02 14.8 0.0 0.031 14.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Lipase_3 PF01764.25 ABK71177.1 - 0.035 14.0 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Hydrolase_4 PF12146.8 ABK71177.1 - 0.051 12.8 0.0 0.092 12.0 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 ABK71177.1 - 0.16 11.5 0.0 0.4 10.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Lactamase_B_2 PF12706.7 ABK71178.1 - 2.4e-35 121.9 0.0 2.8e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TetR_N PF00440.23 ABK71179.1 - 1.9e-09 37.2 0.0 3.5e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_13 PF16925.5 ABK71179.1 - 0.017 15.0 0.1 0.035 14.0 0.0 1.5 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Sigma70_r4_2 PF08281.12 ABK71179.1 - 0.027 14.1 0.0 0.053 13.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 TetR_C_31 PF17940.1 ABK71179.1 - 0.086 13.1 6.4 0.061 13.5 4.0 2.0 1 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Terminase_5 PF06056.12 ABK71179.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) SSF PF00474.17 ABK71180.1 - 5e-44 150.8 32.2 5e-44 150.8 32.2 1.6 2 0 0 2 2 2 1 Sodium:solute symporter family Phage_holin_2_1 PF04971.12 ABK71180.1 - 0.026 14.5 1.0 0.2 11.7 1.0 2.7 1 0 0 1 1 1 0 Bacteriophage P21 holin S SBP_bac_3 PF00497.20 ABK71181.1 - 8.6e-54 182.3 0.0 1.2e-53 181.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 ABK71181.1 - 0.00015 22.0 0.1 0.00047 20.3 0.1 1.7 1 1 1 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site NMT1 PF09084.11 ABK71181.1 - 0.0023 17.9 0.1 0.0033 17.4 0.1 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 ABK71181.1 - 0.14 11.7 0.3 1.1 8.8 0.3 2.2 1 1 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein adh_short PF00106.25 ABK71182.1 - 1.1e-37 129.4 0.1 1.4e-37 129.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK71182.1 - 6.1e-24 84.9 0.1 7.8e-24 84.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK71182.1 - 2.4e-12 47.1 0.5 3.3e-12 46.7 0.5 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK71182.1 - 2.1e-07 30.7 0.5 8.9e-07 28.6 0.5 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 ABK71182.1 - 0.00069 20.1 0.1 0.0015 19.0 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.6 ABK71182.1 - 0.0064 16.4 0.5 0.0081 16.1 0.5 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 ABK71182.1 - 0.024 14.0 0.0 0.27 10.6 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 ABK71182.1 - 0.056 12.5 0.4 0.078 12.1 0.4 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Glyco_tran_WecB PF03808.13 ABK71182.1 - 0.077 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Polysacc_synt_2 PF02719.15 ABK71182.1 - 0.15 11.2 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TetR_C_33 PF13305.6 ABK71184.1 - 2.8e-26 92.3 2.9 2.8e-26 92.3 2.9 2.2 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK71184.1 - 5.2e-06 26.1 0.1 7.8e-05 22.4 0.0 2.5 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_23 PF13384.6 ABK71184.1 - 0.021 14.6 0.0 0.056 13.3 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_31 PF13560.6 ABK71184.1 - 0.058 13.7 2.4 0.18 12.2 2.4 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_IclR PF09339.10 ABK71184.1 - 0.061 13.1 0.1 0.2 11.5 0.1 1.9 2 0 0 2 2 2 0 IclR helix-turn-helix domain zf-RING_7 PF02591.15 ABK71185.1 - 0.017 15.3 0.1 0.047 13.9 0.1 1.8 1 0 0 1 1 1 0 C4-type zinc ribbon domain GcpE PF04551.14 ABK71185.1 - 0.029 13.5 0.1 0.035 13.2 0.1 1.1 1 0 0 1 1 1 0 GcpE protein Sugar-bind PF04198.13 ABK71186.1 - 2.8e-59 200.3 0.0 3.3e-59 200.1 0.0 1.0 1 0 0 1 1 1 1 Putative sugar-binding domain MarR_2 PF12802.7 ABK71186.1 - 0.00015 21.6 1.1 0.00063 19.6 0.1 2.5 3 0 0 3 3 3 1 MarR family Sigma70_r4 PF04545.16 ABK71186.1 - 0.0069 15.9 0.0 0.019 14.5 0.0 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_Crp_2 PF13545.6 ABK71186.1 - 0.056 13.4 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain TFIIE_alpha PF02002.17 ABK71186.1 - 0.19 11.6 0.0 1.2 9.1 0.0 2.0 2 0 0 2 2 2 0 TFIIE alpha subunit PAP2 PF01569.21 ABK71187.1 - 3.2e-14 52.8 4.3 3.2e-14 52.8 4.3 2.1 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 ABK71187.1 - 6e-08 32.6 7.2 9.2e-08 32.0 7.2 1.3 1 1 0 1 1 1 1 PAP2 superfamily Cyt_bd_oxida_II PF02322.15 ABK71187.1 - 0.028 13.8 5.2 0.035 13.5 5.2 1.1 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II DUF212 PF02681.14 ABK71187.1 - 0.33 11.1 5.3 0.79 9.9 0.4 2.7 1 1 2 3 3 3 0 Divergent PAP2 family Acyl-CoA_dh_N PF02771.16 ABK71188.1 - 7.3e-07 29.8 0.0 1.7e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain DUF3027 PF11228.8 ABK71188.1 - 0.011 15.7 0.6 0.019 15.0 0.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3027) FCD PF07729.12 ABK71189.1 - 1.2e-22 80.7 11.8 1.9e-22 80.0 11.8 1.3 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 ABK71189.1 - 2.3e-13 49.6 0.5 4.5e-13 48.6 0.5 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 ABK71189.1 - 0.071 12.7 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding dCache_3 PF14827.6 ABK71189.1 - 0.09 12.4 0.2 0.36 10.4 0.1 1.9 2 0 0 2 2 2 0 Double sensory domain of two-component sensor kinase RsgA_GTPase PF03193.16 ABK71190.1 - 1.4e-43 148.6 0.0 1.9e-43 148.2 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 ABK71190.1 - 1.6e-06 28.1 0.0 3.3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 ABK71190.1 - 5e-05 23.8 0.1 8.6e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 ABK71190.1 - 0.00021 21.7 0.1 0.00076 19.9 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain MobB PF03205.14 ABK71190.1 - 0.006 16.5 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.6 ABK71190.1 - 0.0065 16.2 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.27 ABK71190.1 - 0.013 15.0 0.9 1.2 8.7 0.1 2.8 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 ABK71190.1 - 0.015 15.5 0.1 0.041 14.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 ABK71190.1 - 0.016 14.7 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B Roc PF08477.13 ABK71190.1 - 0.029 14.6 0.1 0.053 13.7 0.1 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 ABK71190.1 - 0.044 14.1 0.1 0.086 13.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain AIG1 PF04548.16 ABK71190.1 - 0.05 12.9 0.1 0.14 11.5 0.0 1.6 2 0 0 2 2 2 0 AIG1 family cobW PF02492.19 ABK71190.1 - 0.1 12.2 0.0 0.71 9.4 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 ABK71190.1 - 0.14 12.5 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 ABK71190.1 - 0.16 11.8 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Septin PF00735.18 ABK71190.1 - 0.29 10.4 0.0 0.42 9.8 0.0 1.2 1 0 0 1 1 1 0 Septin TetR_N PF00440.23 ABK71191.1 - 1.1e-11 44.3 0.1 3.3e-11 42.8 0.1 1.9 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 ABK71191.1 - 0.05 13.8 3.0 0.05 13.8 3.0 2.7 3 1 0 3 3 3 0 BetI-type transcriptional repressor, C-terminal TetR_C_31 PF17940.1 ABK71191.1 - 0.42 10.9 18.9 0.097 12.9 7.7 2.9 1 1 2 3 3 3 0 Tetracyclin repressor-like, C-terminal domain kleA_kleC PF17383.2 ABK71191.1 - 2.2 8.7 5.6 0.73 10.2 2.5 1.8 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A Fer2_2 PF01799.20 ABK71192.1 - 4e-29 100.4 0.9 4e-29 100.4 0.9 1.6 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fer2 PF00111.27 ABK71192.1 - 1.9e-08 34.1 5.5 5.1e-08 32.8 0.4 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 ABK71192.1 - 0.00057 19.9 4.7 0.024 14.7 3.0 2.6 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 ABK71192.1 - 0.0071 16.3 1.5 0.0071 16.3 1.5 2.2 1 1 1 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Tricorn_PDZ PF14685.6 ABK71192.1 - 0.033 14.1 0.1 1.2 9.2 0.0 2.5 1 1 1 2 2 2 0 Tricorn protease PDZ domain DDE_Tnp_ISL3 PF01610.17 ABK71194.1 - 3.1e-50 171.1 0.0 4.4e-50 170.6 0.0 1.2 1 0 0 1 1 1 1 Transposase zf-ISL3 PF14690.6 ABK71194.1 - 3.2e-11 43.7 6.9 4.2e-10 40.1 3.8 2.9 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HTH_Tnp_ISL3 PF13542.6 ABK71194.1 - 3.4e-10 39.2 0.3 3.4e-10 39.2 0.3 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain of transposase family ISL3 Rubredoxin_2 PF18073.1 ABK71194.1 - 0.011 15.4 2.1 0.012 15.4 0.2 2.1 2 0 0 2 2 2 0 Rubredoxin metal binding domain ABC_tran PF00005.27 ABK71195.1 - 5.1e-28 98.3 0.0 7.7e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK71195.1 - 2.8e-07 30.7 0.1 0.021 14.6 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ABK71195.1 - 0.0011 19.2 0.1 0.022 15.0 0.1 2.2 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 ABK71195.1 - 0.0012 18.3 0.2 0.93 8.9 0.2 2.2 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ABK71195.1 - 0.0045 17.4 0.3 0.0066 16.8 0.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 ABK71195.1 - 0.0075 16.0 0.4 0.014 15.2 0.4 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ABK71195.1 - 0.0079 16.1 0.1 0.013 15.4 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 ABK71195.1 - 0.0083 15.9 0.1 0.034 13.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 ABK71195.1 - 0.01 15.2 0.0 0.12 11.7 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 ABK71195.1 - 0.013 14.6 0.1 0.02 14.0 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NB-ARC PF00931.22 ABK71195.1 - 0.017 14.3 0.2 0.054 12.7 0.1 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.6 ABK71195.1 - 0.017 15.4 0.1 0.11 12.8 0.1 2.1 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ABK71195.1 - 0.045 13.8 0.0 0.16 12.0 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 ABK71195.1 - 0.049 13.8 0.3 0.061 13.5 0.3 1.6 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 ABK71195.1 - 0.069 12.7 0.2 0.14 11.7 0.2 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 ABK71195.1 - 0.098 13.1 0.2 0.7 10.3 0.2 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 ABK71195.1 - 0.12 12.9 0.7 0.21 12.1 0.7 1.3 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 ABK71195.1 - 0.13 12.5 0.5 0.91 9.8 0.5 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RNA12 PF10443.9 ABK71195.1 - 0.16 10.7 1.2 0.22 10.2 0.2 1.6 2 0 0 2 2 2 0 RNA12 protein ATP_bind_1 PF03029.17 ABK71195.1 - 0.16 11.7 0.1 0.25 11.1 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ABC_ATPase PF09818.9 ABK71195.1 - 0.18 10.6 0.1 5.1 5.8 0.1 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Ald_Xan_dh_C2 PF02738.18 ABK71196.1 - 5.6e-146 487.2 0.1 7.5e-146 486.8 0.1 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 ABK71196.1 - 2.9e-24 85.6 1.8 1.5e-23 83.2 0.5 2.4 2 0 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain AAA_22 PF13401.6 ABK71197.1 - 1.8e-10 41.2 0.0 0.001 19.4 0.0 3.9 3 1 0 4 4 4 2 AAA domain DUF87 PF01935.17 ABK71197.1 - 2e-10 41.2 0.0 5.1e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_16 PF13191.6 ABK71197.1 - 9.7e-08 32.6 12.1 2.4e-07 31.3 2.4 4.3 3 2 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.6 ABK71197.1 - 4.1e-06 26.6 0.1 0.0029 17.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 ABK71197.1 - 4.7e-05 23.4 1.2 0.24 11.3 0.1 3.5 3 0 0 3 3 3 1 NACHT domain AAA_19 PF13245.6 ABK71197.1 - 0.00019 21.8 0.0 0.25 11.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ABK71197.1 - 0.00049 20.3 0.0 0.9 9.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain Zot PF05707.12 ABK71197.1 - 0.0011 18.7 0.0 0.0029 17.3 0.0 1.7 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) TrwB_AAD_bind PF10412.9 ABK71197.1 - 0.0012 17.9 0.3 0.0094 14.9 0.0 2.4 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain ATP_bind_1 PF03029.17 ABK71197.1 - 0.0019 18.0 0.0 1.5 8.6 0.0 2.6 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.18 ABK71197.1 - 0.0024 17.3 0.1 0.011 15.1 0.0 2.1 2 0 0 2 2 2 1 FtsK/SpoIIIE family Zeta_toxin PF06414.12 ABK71197.1 - 0.0038 16.5 0.1 0.66 9.2 0.0 3.0 3 0 0 3 3 3 1 Zeta toxin DUF853 PF05872.12 ABK71197.1 - 0.0069 15.0 0.0 0.023 13.3 0.0 1.8 3 0 0 3 3 3 1 Bacterial protein of unknown function (DUF853) MobB PF03205.14 ABK71197.1 - 0.033 14.1 0.1 0.32 10.9 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 ABK71197.1 - 0.036 14.6 0.0 11 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 ABK71197.1 - 0.041 13.5 0.2 7.4 6.1 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.18 ABK71197.1 - 0.064 13.0 0.0 14 5.3 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 ABK71197.1 - 0.083 12.8 0.0 4.4 7.2 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea UvrD-helicase PF00580.21 ABK71197.1 - 0.13 11.8 0.6 5.1 6.5 0.0 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_10 PF12846.7 ABK71197.1 - 0.13 11.1 0.0 0.28 10.1 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain TsaE PF02367.17 ABK71197.1 - 0.15 12.1 0.1 15 5.6 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE KAP_NTPase PF07693.14 ABK71197.1 - 0.16 11.2 0.0 0.64 9.2 0.0 1.8 2 0 0 2 2 2 0 KAP family P-loop domain ResIII PF04851.15 ABK71197.1 - 0.17 11.9 0.0 8.1 6.4 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Aldedh PF00171.22 ABK71198.1 - 8.8e-156 519.0 3.8 9.9e-156 518.8 3.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AAA_18 PF13238.6 ABK71199.1 - 5.6e-07 30.2 0.0 7.7e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 ABK71199.1 - 6.5e-06 26.2 0.0 1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ABK71199.1 - 2.2e-05 24.9 0.1 5e-05 23.7 0.0 1.5 1 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 ABK71199.1 - 0.00021 21.5 0.0 0.00059 20.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ABK71199.1 - 0.00041 20.1 0.1 0.00049 19.9 0.1 1.4 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 ABK71199.1 - 0.0056 16.4 0.0 0.043 13.6 0.0 1.9 2 0 0 2 2 2 1 Cytidylate kinase AAA_22 PF13401.6 ABK71199.1 - 0.0074 16.6 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 ABK71199.1 - 0.0076 16.2 0.1 0.011 15.8 0.1 1.2 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 ABK71199.1 - 0.0084 16.1 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) PRK PF00485.18 ABK71199.1 - 0.014 15.1 0.0 0.28 10.9 0.0 2.0 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.6 ABK71199.1 - 0.017 14.9 0.5 0.09 12.5 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 ABK71199.1 - 0.017 14.4 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 ABK71199.1 - 0.022 13.9 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activat PF00158.26 ABK71199.1 - 0.028 14.1 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain dNK PF01712.19 ABK71199.1 - 0.032 14.1 0.0 0.048 13.5 0.0 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase ABC_tran PF00005.27 ABK71199.1 - 0.037 14.5 0.0 0.056 13.9 0.0 1.2 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 ABK71199.1 - 0.037 14.4 0.0 0.059 13.8 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 ABK71199.1 - 0.046 13.4 0.0 0.064 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 ABK71199.1 - 0.049 13.1 0.0 0.064 12.7 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit APS_kinase PF01583.20 ABK71199.1 - 0.061 13.2 0.0 0.097 12.6 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase ATPase PF06745.13 ABK71199.1 - 0.062 12.6 0.0 0.086 12.2 0.0 1.1 1 0 0 1 1 1 0 KaiC AAA_28 PF13521.6 ABK71199.1 - 0.064 13.5 0.0 0.12 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain Toxin_4 PF00706.17 ABK71199.1 - 0.076 13.5 0.2 0.15 12.5 0.2 1.4 1 0 0 1 1 1 0 Anenome neurotoxin TIP49 PF06068.13 ABK71199.1 - 0.085 12.0 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain Lipid_DES PF08557.10 ABK71199.1 - 0.09 12.3 0.7 0.21 11.1 0.1 1.8 2 0 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) PduV-EutP PF10662.9 ABK71199.1 - 0.092 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 ABK71199.1 - 0.095 12.5 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA PF00004.29 ABK71199.1 - 0.13 12.7 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 ABK71199.1 - 0.18 11.7 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_14 PF13173.6 ABK71199.1 - 0.19 11.8 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 ABK71199.1 - 0.19 11.6 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 NTPase cobW PF02492.19 ABK71199.1 - 0.19 11.3 0.0 0.54 9.8 0.0 1.8 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain CBP_BcsF PF11120.8 ABK71199.1 - 0.2 11.8 0.2 0.48 10.6 0.2 1.6 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsF Transglycosylas PF06737.14 ABK71200.1 - 5e-34 116.8 8.5 8e-34 116.1 8.5 1.3 1 0 0 1 1 1 1 Transglycosylase-like domain NLPC_P60 PF00877.19 ABK71201.1 - 1.5e-25 89.2 0.0 3.9e-25 87.9 0.0 1.7 1 0 0 1 1 1 1 NlpC/P60 family Peptidase_C92 PF05708.12 ABK71201.1 - 1.6e-05 25.1 0.0 0.02 15.0 0.0 3.3 3 1 0 3 3 3 2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family LRAT PF04970.13 ABK71201.1 - 0.011 16.0 1.3 0.019 15.3 0.0 2.0 2 1 1 3 3 3 0 Lecithin retinol acyltransferase Amidase_5 PF05382.13 ABK71201.1 - 0.12 12.2 0.6 0.68 9.8 0.6 2.0 1 1 0 1 1 1 0 Bacteriophage peptidoglycan hydrolase CHAP PF05257.16 ABK71201.1 - 0.14 12.7 0.1 0.41 11.3 0.1 1.8 1 0 0 1 1 1 0 CHAP domain Filament PF00038.21 ABK71201.1 - 3.9 7.0 14.6 4.2e+02 0.3 14.6 2.1 1 1 0 1 1 1 0 Intermediate filament protein CPSF100_C PF13299.6 ABK71201.1 - 7 6.8 8.2 4.8 7.3 0.9 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal HAUS6_N PF14661.6 ABK71201.1 - 9.7 5.7 12.3 1.2 8.7 1.7 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus bPH_2 PF03703.14 ABK71202.1 - 3.4e-14 52.8 0.2 5.1e-14 52.2 0.2 1.4 1 0 0 1 1 1 1 Bacterial PH domain DUF2897 PF11446.8 ABK71203.1 - 0.0093 15.8 1.4 0.014 15.2 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2897) Adeno_E3 PF06040.11 ABK71203.1 - 0.21 11.7 0.1 0.21 11.7 0.1 1.1 1 0 0 1 1 1 0 Adenovirus E3 protein TylF PF05711.11 ABK71204.1 - 1.3e-13 50.9 0.0 1.7e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) Methyltransf_24 PF13578.6 ABK71204.1 - 1.5e-11 45.3 0.0 3e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 ABK71205.1 - 9e-22 78.0 0.0 1.1e-21 77.7 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase S4 PF01479.25 ABK71205.1 - 2.7e-08 33.4 0.1 6.9e-08 32.1 0.1 1.7 1 0 0 1 1 1 1 S4 domain cNMP_binding PF00027.29 ABK71206.1 - 1.1e-24 86.3 0.0 1.9e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 ABK71206.1 - 1.2e-17 63.6 2.9 1.3e-17 63.5 0.7 2.1 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain Crp PF00325.20 ABK71206.1 - 2.1e-05 24.0 0.0 5.7e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, crp family MarR_2 PF12802.7 ABK71206.1 - 0.00015 21.6 0.6 0.00059 19.7 0.6 2.1 1 1 0 1 1 1 1 MarR family GntR PF00392.21 ABK71206.1 - 0.00017 21.2 0.4 0.0006 19.4 0.1 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family Sigma70_r4 PF04545.16 ABK71206.1 - 0.00018 21.0 0.0 0.00042 19.8 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_24 PF13412.6 ABK71206.1 - 0.0032 17.0 0.2 0.014 14.9 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Sigma70_r4_2 PF08281.12 ABK71206.1 - 0.0037 16.9 0.1 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_29 PF13551.6 ABK71206.1 - 0.004 17.1 0.5 0.02 14.9 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn helix HTH_36 PF13730.6 ABK71206.1 - 0.0051 16.7 0.0 0.0096 15.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 ABK71206.1 - 0.0075 16.0 0.2 0.027 14.3 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_3 PF01381.22 ABK71206.1 - 0.008 16.2 0.0 0.073 13.1 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix HTH_IclR PF09339.10 ABK71206.1 - 0.02 14.7 1.0 0.13 12.0 0.0 2.4 2 1 0 2 2 2 0 IclR helix-turn-helix domain HTH_28 PF13518.6 ABK71206.1 - 0.029 14.5 1.0 0.094 12.9 0.1 2.2 2 1 0 2 2 2 0 Helix-turn-helix domain TrmB PF01978.19 ABK71206.1 - 0.047 13.6 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB MarR PF01047.22 ABK71206.1 - 0.069 13.1 0.0 0.28 11.1 0.0 2.0 2 0 0 2 2 2 0 MarR family HTH_31 PF13560.6 ABK71206.1 - 0.074 13.4 4.3 0.13 12.6 0.1 2.7 3 0 0 3 3 2 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 ABK71206.1 - 0.078 12.8 2.6 2.8 7.9 0.1 3.0 2 1 0 2 2 2 0 AsnC-type helix-turn-helix domain Rrf2 PF02082.20 ABK71206.1 - 0.08 13.3 0.1 0.78 10.1 0.0 2.4 2 0 0 2 2 2 0 Transcriptional regulator ECH_1 PF00378.20 ABK71207.1 - 5.5e-57 193.0 0.0 6.2e-57 192.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK71207.1 - 3.2e-29 102.5 2.4 8.1e-26 91.3 0.7 2.4 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase SDH_sah PF01972.16 ABK71207.1 - 0.037 13.0 0.0 0.06 12.3 0.0 1.3 1 0 0 1 1 1 0 Serine dehydrogenase proteinase MarR PF01047.22 ABK71208.1 - 7.5e-08 32.2 0.0 1.4e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 ABK71208.1 - 5.7e-07 29.3 0.2 5.7e-07 29.3 0.2 2.0 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 ABK71208.1 - 1.4e-06 28.6 0.3 5.5e-06 26.8 0.0 2.0 2 1 0 2 2 2 1 Winged helix DNA-binding domain HTH_1 PF00126.27 ABK71208.1 - 0.0022 17.9 0.3 0.051 13.5 0.1 2.6 2 1 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family Fe_dep_repress PF01325.19 ABK71208.1 - 0.0027 17.9 0.0 0.0044 17.2 0.0 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_42 PF06224.12 ABK71208.1 - 0.011 15.3 2.7 0.063 12.8 1.4 1.9 1 1 1 2 2 2 0 Winged helix DNA-binding domain DUF3989 PF13150.6 ABK71208.1 - 0.32 10.8 1.3 1.3 8.8 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) Acyl-CoA_dh_1 PF00441.24 ABK71210.1 - 5.4e-24 85.1 5.1 9e-24 84.4 5.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK71210.1 - 9.6e-18 64.9 2.8 1.2e-17 64.5 0.6 2.3 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ABK71210.1 - 5.3e-05 23.3 0.6 0.00014 21.9 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Yip1 PF04893.17 ABK71211.1 - 0.05 13.3 22.6 0.0065 16.2 15.2 2.1 1 1 1 2 2 2 0 Yip1 domain DUF1118 PF06549.12 ABK71211.1 - 5.4 7.4 12.2 0.11 12.8 1.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1118) Glyco_transf_28 PF03033.20 ABK71212.1 - 5.4e-08 33.0 0.0 1.2e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_transf_4 PF13439.6 ABK71212.1 - 0.031 14.3 0.1 0.14 12.2 0.1 2.1 1 1 0 1 1 1 0 Glycosyltransferase Family 4 Transpeptidase PF00905.22 ABK71213.1 - 1.4e-75 254.3 0.0 1.9e-75 253.9 0.0 1.2 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain PDDEXK_1 PF12705.7 ABK71214.1 - 5.2e-41 141.3 0.1 5.9e-41 141.1 0.1 1.0 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.17 ABK71214.1 - 0.0025 17.9 0.0 0.0036 17.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF83 TetR_N PF00440.23 ABK71215.1 - 4.2e-14 52.0 0.9 8.8e-14 51.0 0.1 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 ABK71215.1 - 0.0027 18.0 2.3 0.0027 18.0 2.3 2.4 3 0 0 3 3 3 1 Tetracyclin repressor-like, C-terminal domain TetR_C_13 PF16925.5 ABK71215.1 - 0.007 16.3 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain ParD_antitoxin PF03693.14 ABK71215.1 - 0.11 13.0 0.1 1.1 9.7 0.0 2.5 3 0 0 3 3 3 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH HTH_18 PF12833.7 ABK71216.1 - 1.7e-22 79.5 0.4 2.6e-22 78.9 0.4 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain DJ-1_PfpI PF01965.24 ABK71216.1 - 2.8e-17 63.0 0.0 4.5e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family HTH_AraC PF00165.23 ABK71216.1 - 1.9e-16 59.7 0.0 6.1e-09 35.8 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family TetR_N PF00440.23 ABK71216.1 - 0.017 14.9 0.2 0.064 13.1 0.1 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family HTH_Tnp_ISL3 PF13542.6 ABK71216.1 - 0.031 13.7 0.3 0.56 9.7 0.5 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_31 PF13560.6 ABK71216.1 - 0.95 9.9 6.2 2.5 8.5 0.3 3.3 2 1 1 3 3 3 0 Helix-turn-helix domain AA_permease_2 PF13520.6 ABK71217.1 - 2.2e-41 142.1 37.7 2.7e-41 141.8 37.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ABK71217.1 - 1.3e-21 76.8 31.5 1.8e-21 76.3 31.5 1.2 1 0 0 1 1 1 1 Amino acid permease Tmemb_9 PF05434.11 ABK71217.1 - 0.25 11.2 0.0 0.63 9.9 0.0 1.6 1 0 0 1 1 1 0 TMEM9 PhyH PF05721.13 ABK71218.1 - 5.8e-26 92.1 0.0 7.3e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DEDD_Tnp_IS110 PF01548.17 ABK71219.1 - 1.1e-46 158.5 0.7 1.9e-46 157.7 0.2 1.6 2 0 0 2 2 2 1 Transposase Transposase_20 PF02371.16 ABK71219.1 - 8.4e-24 83.7 1.1 1.6e-23 82.9 0.1 2.0 2 0 0 2 2 2 1 Transposase IS116/IS110/IS902 family Crr6 PF08847.11 ABK71219.1 - 0.11 12.2 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Chlororespiratory reduction 6 HATPase_c_2 PF13581.6 ABK71220.1 - 3e-06 27.2 0.5 4.7e-06 26.6 0.5 1.5 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain GATase_3 PF07685.14 ABK71221.1 - 7.3e-38 130.1 0.0 8.4e-38 129.9 0.0 1.0 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 ABK71221.1 - 0.025 14.4 0.0 0.037 13.8 0.0 1.2 1 0 0 1 1 1 0 DJ-1/PfpI family GATase_6 PF13522.6 ABK71222.1 - 2.5e-16 60.1 0.2 5.8e-16 58.9 0.1 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 ABK71222.1 - 1.5e-14 53.9 0.0 2e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase domain ADH_N PF08240.12 ABK71223.1 - 1.3e-16 60.5 0.8 1.3e-16 60.5 0.8 2.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ABK71223.1 - 1.1e-15 57.8 2.6 2.3e-15 56.7 2.6 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ABK71223.1 - 1.7e-05 24.5 4.9 3.7e-05 23.3 4.9 1.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N_assoc PF13823.6 ABK71223.1 - 1.8e-05 24.6 0.2 4.5e-05 23.3 0.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.6 ABK71223.1 - 3.3e-05 25.0 0.3 6.7e-05 24.0 0.2 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ECH_1 PF00378.20 ABK71224.1 - 2.5e-51 174.4 0.0 3.9e-51 173.8 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK71224.1 - 1.7e-29 103.4 0.1 2.9e-28 99.3 0.1 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 ABK71224.1 - 0.074 13.0 1.2 1.5 8.8 0.1 2.6 3 0 0 3 3 3 0 Peptidase family S49 SnoaL_2 PF12680.7 ABK71225.1 - 2.6e-12 47.3 0.0 3.5e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain NTF2 PF02136.20 ABK71225.1 - 9.3e-10 39.1 0.0 1.2e-09 38.7 0.0 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 ABK71225.1 - 0.00013 22.3 0.0 0.00022 21.6 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) BPD_transp_1 PF00528.22 ABK71226.1 - 1.7e-26 93.1 12.8 1.7e-26 93.1 12.8 1.5 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF3375 PF11855.8 ABK71227.1 - 1.5e-141 472.6 17.5 1.7e-141 472.4 17.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3375) DnaG_DnaB_bind PF08278.11 ABK71227.1 - 0.11 13.1 6.2 0.085 13.5 1.0 3.0 2 1 1 3 3 3 0 DNA primase DnaG DnaB-binding Nup54 PF13874.6 ABK71227.1 - 0.14 12.2 1.4 1.1 9.4 0.3 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 HisKA_3 PF07730.13 ABK71227.1 - 0.25 11.9 7.9 4 8.0 1.0 3.0 2 0 0 2 2 2 0 Histidine kinase FlgN PF05130.12 ABK71227.1 - 0.97 9.9 3.3 25 5.4 0.7 2.4 2 0 0 2 2 2 0 FlgN protein Vir_act_alpha_C PF10400.9 ABK71227.1 - 7.2 7.4 9.3 22 5.8 4.0 3.2 2 1 0 2 2 2 0 Virulence activator alpha C-term PMT_2 PF13231.6 ABK71228.1 - 7.1e-26 91.3 16.9 7.1e-26 91.3 16.9 3.7 3 1 1 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase STT3 PF02516.14 ABK71228.1 - 1 8.2 21.9 0.036 13.0 12.8 2.2 2 0 0 2 2 2 0 Oligosaccharyl transferase STT3 subunit Bac_luciferase PF00296.20 ABK71229.1 - 7.7e-50 170.1 3.6 1.2e-49 169.5 3.6 1.3 1 1 0 1 1 1 1 Luciferase-like monooxygenase Pyr_redox_3 PF13738.6 ABK71230.1 - 1.7e-14 53.8 0.0 6.2e-14 52.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ABK71230.1 - 8.8e-14 50.8 0.0 3.4e-13 48.9 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 ABK71230.1 - 3.5e-13 49.5 0.0 5.6e-11 42.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ABK71230.1 - 1.3e-10 41.4 0.7 2.3e-08 34.2 0.1 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 ABK71230.1 - 1.6e-08 34.1 0.3 9.1e-08 31.6 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 ABK71230.1 - 3.9e-07 30.0 3.3 0.00097 18.8 0.1 3.4 1 1 2 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ABK71230.1 - 4.9e-07 29.9 2.2 4e-06 26.9 0.2 3.1 3 1 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 ABK71230.1 - 3e-05 23.3 0.0 0.00049 19.3 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 ABK71230.1 - 0.0002 20.2 1.6 0.091 11.4 0.2 2.7 4 0 0 4 4 4 2 HI0933-like protein Lycopene_cycl PF05834.12 ABK71230.1 - 0.00055 19.1 0.0 0.0045 16.1 0.0 2.2 1 1 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 ABK71230.1 - 0.0027 16.9 0.1 0.2 10.7 0.0 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.17 ABK71230.1 - 0.0028 16.9 0.2 0.12 11.6 0.1 2.4 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 ABK71230.1 - 0.033 13.5 0.0 0.057 12.7 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 ABK71230.1 - 0.058 14.0 0.5 1.7 9.3 0.1 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF1854 PF08909.11 ABK71230.1 - 0.063 13.1 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1854) AlaDh_PNT_C PF01262.21 ABK71230.1 - 0.18 11.1 0.0 2.1 7.6 0.0 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Arr-ms PF12120.8 ABK71231.1 - 2.4e-48 162.4 0.0 2.9e-48 162.1 0.0 1.1 1 0 0 1 1 1 1 Rifampin ADP-ribosyl transferase Transp_cyt_pur PF02133.15 ABK71233.1 - 1.8e-47 162.1 47.6 5.5e-47 160.6 47.6 1.6 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin IclR PF01614.18 ABK71234.1 - 3e-24 85.3 0.0 4.7e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 ABK71234.1 - 1.1e-12 47.5 0.1 2.6e-12 46.3 0.1 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 ABK71234.1 - 4.5e-06 26.5 0.1 5e-05 23.1 0.0 2.5 2 1 0 2 2 2 1 MarR family HTH_24 PF13412.6 ABK71234.1 - 0.0012 18.4 0.1 0.0048 16.4 0.0 2.1 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 ABK71234.1 - 0.0023 17.8 0.0 0.0043 16.9 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DUF742 PF05331.11 ABK71234.1 - 0.04 13.7 0.1 0.091 12.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF742) HTH_20 PF12840.7 ABK71234.1 - 0.048 13.7 0.0 2.5 8.2 0.0 2.8 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_40 PF14493.6 ABK71234.1 - 0.16 12.5 0.0 0.38 11.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Sulfolobus_pRN PF05584.11 ABK71234.1 - 0.18 11.8 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 Sulfolobus plasmid regulatory protein Bac_luciferase PF00296.20 ABK71235.1 - 4.3e-56 190.6 7.2 5.6e-56 190.3 7.2 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF885 PF05960.11 ABK71236.1 - 8.2e-151 504.2 0.7 9.4e-151 504.0 0.7 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) dTDP_sugar_isom PF00908.17 ABK71239.1 - 2.1e-59 200.0 0.0 2.4e-59 199.8 0.0 1.0 1 0 0 1 1 1 1 dTDP-4-dehydrorhamnose 3,5-epimerase FdtA PF05523.11 ABK71239.1 - 0.052 13.3 0.0 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 WxcM-like, C-terminal Carb_kinase PF01256.17 ABK71240.1 - 6.7e-67 225.5 3.4 9.5e-67 225.0 3.4 1.2 1 0 0 1 1 1 1 Carbohydrate kinase YjeF_N PF03853.15 ABK71240.1 - 3.5e-35 121.4 2.3 3.5e-35 121.4 2.3 2.1 2 1 0 2 2 2 1 YjeF-related protein N-terminus Phos_pyr_kin PF08543.12 ABK71240.1 - 0.00012 21.6 0.1 0.00042 19.8 0.0 1.9 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase HK PF02110.15 ABK71240.1 - 0.016 14.6 0.1 0.035 13.5 0.1 1.5 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family GATase_6 PF13522.6 ABK71241.1 - 3.1e-15 56.5 0.5 9.6e-15 55.0 0.2 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 ABK71241.1 - 2e-13 50.3 0.0 1.4e-12 47.6 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 ABK71241.1 - 5.2e-08 32.6 0.0 1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_2 PF00310.21 ABK71241.1 - 7.4e-06 24.9 0.2 0.031 13.0 0.0 3.0 1 1 2 3 3 3 3 Glutamine amidotransferases class-II GATase_4 PF13230.6 ABK71241.1 - 0.00037 19.5 0.0 0.00064 18.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Peripla_BP_2 PF01497.18 ABK71242.1 - 7e-23 81.4 0.1 8.8e-23 81.1 0.1 1.2 1 0 0 1 1 1 1 Periplasmic binding protein YfdX PF10938.8 ABK71242.1 - 0.031 14.2 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 YfdX protein TylF PF05711.11 ABK71242.1 - 0.14 11.4 0.1 0.21 10.8 0.1 1.2 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) ABC_tran PF00005.27 ABK71243.1 - 1.5e-43 148.6 0.0 4.1e-22 79.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ABK71243.1 - 6.9e-12 45.8 0.7 3.9e-05 23.6 0.0 3.7 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK71243.1 - 7.5e-11 41.9 0.2 0.042 13.3 0.0 4.1 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ABK71243.1 - 1e-08 34.8 0.3 0.0069 16.1 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 ABK71243.1 - 2.6e-07 31.2 3.6 0.00053 20.4 0.4 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 ABK71243.1 - 4.8e-07 30.1 0.2 0.0027 18.0 0.0 3.0 2 2 0 2 2 2 2 AAA domain AAA_23 PF13476.6 ABK71243.1 - 1.3e-06 29.1 0.1 0.071 13.6 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 ABK71243.1 - 6.4e-05 23.1 1.7 0.034 14.3 0.0 2.8 3 0 0 3 3 2 1 AAA domain SbcCD_C PF13558.6 ABK71243.1 - 8.6e-05 22.7 1.9 0.42 10.9 0.1 3.9 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 ABK71243.1 - 0.00016 21.5 5.2 0.003 17.3 1.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 ABK71243.1 - 0.00046 20.6 1.3 0.22 12.0 0.3 3.5 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 ABK71243.1 - 0.00096 19.1 1.3 0.75 9.7 0.1 2.6 2 0 0 2 2 2 2 NACHT domain IstB_IS21 PF01695.17 ABK71243.1 - 0.0013 18.5 1.7 14 5.3 0.0 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_13 PF13166.6 ABK71243.1 - 0.0016 17.2 0.5 0.13 10.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 ABK71243.1 - 0.0017 17.7 0.5 0.18 11.2 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family RuvB_N PF05496.12 ABK71243.1 - 0.0024 17.6 0.4 0.96 9.2 0.1 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DUF3584 PF12128.8 ABK71243.1 - 0.0035 15.0 1.7 0.017 12.7 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) AAA_18 PF13238.6 ABK71243.1 - 0.0064 17.0 1.5 0.67 10.5 0.2 2.4 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 ABK71243.1 - 0.0071 16.3 0.3 0.29 11.0 0.0 2.7 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_25 PF13481.6 ABK71243.1 - 0.0073 15.9 7.4 0.37 10.3 0.6 3.4 2 2 0 2 2 2 2 AAA domain AAA_24 PF13479.6 ABK71243.1 - 0.025 14.3 1.5 1.9 8.2 0.1 2.7 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 ABK71243.1 - 0.026 14.8 1.2 0.55 10.5 0.4 2.4 2 0 0 2 2 2 0 AAA domain Ploopntkinase1 PF18748.1 ABK71243.1 - 0.066 12.7 0.0 2.8 7.4 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 AAA_14 PF13173.6 ABK71243.1 - 0.086 12.9 0.1 3 7.9 0.0 2.5 3 0 0 3 3 2 0 AAA domain ATPase_2 PF01637.18 ABK71243.1 - 0.09 12.7 0.0 1.8 8.4 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 ABK71243.1 - 0.092 13.1 0.3 17 5.8 0.0 2.4 2 0 0 2 2 2 0 RNA helicase T2SSE PF00437.20 ABK71243.1 - 0.097 11.7 1.2 1.5 7.8 0.1 2.3 2 1 0 2 2 2 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 ABK71243.1 - 0.11 11.9 0.2 10 5.5 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 ABK71243.1 - 0.12 12.3 2.5 0.38 10.7 0.1 2.5 3 0 0 3 3 3 0 NTPase NB-ARC PF00931.22 ABK71243.1 - 0.12 11.5 1.2 11 5.1 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.19 ABK71243.1 - 0.15 11.6 0.8 0.79 9.3 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DEAD PF00270.29 ABK71243.1 - 0.2 11.4 1.6 19 5.0 0.1 3.1 3 0 0 3 3 3 0 DEAD/DEAH box helicase PhoH PF02562.16 ABK71243.1 - 0.21 11.0 0.4 4.8 6.6 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein RsgA_GTPase PF03193.16 ABK71243.1 - 0.25 11.2 0.9 7.2 6.5 0.1 2.7 3 0 0 3 3 2 0 RsgA GTPase DUF87 PF01935.17 ABK71243.1 - 0.28 11.2 2.5 0.36 10.9 0.1 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain DUF4690 PF15756.5 ABK71243.1 - 0.64 10.7 7.3 5.2 7.7 1.2 3.1 2 0 0 2 2 2 0 Small Novel Rich in Cartilage AAA_5 PF07728.14 ABK71243.1 - 0.73 9.8 2.2 25 4.9 0.1 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Mur_ligase_M PF08245.12 ABK71244.1 - 5.2e-27 95.1 0.0 7.3e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 ABK71244.1 - 2.9e-23 81.9 0.8 1.2e-22 80.0 0.4 2.2 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Mur_ligase PF01225.25 ABK71244.1 - 6.3e-23 80.9 0.6 1.8e-22 79.4 0.1 2.1 2 0 0 2 2 2 1 Mur ligase family, catalytic domain Acyl_transf_3 PF01757.22 ABK71245.1 - 1.6e-12 47.2 40.3 3.7e-12 46.0 40.3 1.5 1 1 0 1 1 1 1 Acyltransferase family Amidohydro_1 PF01979.20 ABK71246.1 - 1.3e-15 57.6 0.0 1.9e-15 57.0 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ABK71246.1 - 0.00043 19.9 9.9 0.004 16.7 3.5 3.1 1 1 0 2 2 2 2 Amidohydrolase family Ribosomal_L31 PF01197.18 ABK71247.1 - 8.3e-32 109.2 0.7 9.4e-32 109.1 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L31 GntP_permease PF02447.16 ABK71248.1 - 1.6e-114 383.0 53.2 1.1e-113 380.3 53.2 1.8 1 1 0 1 1 1 1 GntP family permease CitMHS PF03600.16 ABK71248.1 - 1.6e-30 106.4 41.2 2.7e-30 105.6 41.2 1.3 1 0 0 1 1 1 1 Citrate transporter MarR_2 PF12802.7 ABK71249.1 - 8.7e-10 38.3 0.3 2e-09 37.2 0.3 1.7 1 0 0 1 1 1 1 MarR family MarR PF01047.22 ABK71249.1 - 1.1e-09 38.0 0.0 1.9e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 ABK71249.1 - 1.3e-09 38.4 0.1 2.3e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_20 PF12840.7 ABK71249.1 - 9.8e-05 22.3 0.2 0.00018 21.5 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 ABK71249.1 - 0.0011 18.7 3.7 0.036 13.9 0.4 3.1 3 0 0 3 3 3 1 IclR helix-turn-helix domain GntR PF00392.21 ABK71249.1 - 0.0012 18.4 0.1 0.0012 18.4 0.1 2.3 3 0 0 3 3 3 1 Bacterial regulatory proteins, gntR family Fe_dep_repress PF01325.19 ABK71249.1 - 0.0014 18.8 0.0 0.0027 17.9 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain TrmB PF01978.19 ABK71249.1 - 0.017 15.0 0.0 0.055 13.4 0.0 1.9 2 1 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_1 PF00126.27 ABK71249.1 - 0.017 15.0 0.1 0.038 14.0 0.1 1.7 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_Crp_2 PF13545.6 ABK71249.1 - 0.031 14.3 0.3 0.068 13.2 0.3 1.8 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_34 PF13601.6 ABK71249.1 - 0.044 13.9 0.0 0.068 13.4 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain DUF2250 PF10007.9 ABK71249.1 - 0.048 13.8 0.0 0.096 12.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) HTH_28 PF13518.6 ABK71249.1 - 0.049 13.8 0.2 0.47 10.6 0.0 2.4 3 0 0 3 3 2 0 Helix-turn-helix domain DPBB_1 PF03330.18 ABK71249.1 - 0.067 13.5 0.0 0.15 12.3 0.0 1.6 2 0 0 2 2 1 0 Lytic transglycolase HTH_47 PF16221.5 ABK71249.1 - 0.085 12.4 0.0 0.24 11.0 0.0 1.8 2 1 0 2 2 2 0 winged helix-turn-helix HxlR PF01638.17 ABK71249.1 - 0.088 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 HxlR-like helix-turn-helix HTH_CodY PF08222.11 ABK71249.1 - 0.09 12.3 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 CodY helix-turn-helix domain HTH_23 PF13384.6 ABK71249.1 - 0.14 12.0 1.0 0.32 10.9 0.1 2.0 2 0 0 2 2 2 0 Homeodomain-like domain PadR PF03551.14 ABK71249.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family ADH_N PF08240.12 ABK71250.1 - 5.4e-10 39.1 0.2 2.3e-08 33.9 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ABK71250.1 - 6e-09 37.0 1.0 1.3e-08 35.9 0.3 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ABK71250.1 - 2.5e-07 30.7 0.8 5.3e-07 29.7 0.8 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Helicase_C PF00271.31 ABK71251.1 - 2.2e-20 73.1 0.0 1e-17 64.5 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 ABK71251.1 - 7.5e-18 64.9 0.1 2e-17 63.5 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 ABK71251.1 - 9.7e-09 35.5 0.0 1.8e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit tRNA_anti-codon PF01336.25 ABK71251.1 - 0.00029 20.7 0.0 0.00088 19.2 0.0 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RecG_wedge PF17191.4 ABK71251.1 - 0.0011 18.6 0.0 0.013 15.1 0.0 2.4 2 1 0 2 2 2 1 RecG wedge domain AAA_30 PF13604.6 ABK71251.1 - 0.0014 18.3 1.3 0.0064 16.2 1.4 2.1 2 1 0 2 2 2 1 AAA domain SNF2_N PF00176.23 ABK71251.1 - 0.013 14.2 0.0 0.03 13.0 0.0 1.6 1 1 0 1 1 1 0 SNF2 family N-terminal domain ERCC3_RAD25_C PF16203.5 ABK71251.1 - 0.13 11.4 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Methyltransf_25 PF13649.6 ABK71252.1 - 2.4e-14 53.8 0.0 5.1e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABK71252.1 - 2.2e-13 50.6 0.0 3.9e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK71252.1 - 4.4e-12 46.6 0.0 7.5e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABK71252.1 - 3.7e-10 39.8 0.0 4.9e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABK71252.1 - 7.9e-06 25.8 0.0 1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ABK71252.1 - 0.00062 19.2 0.0 0.00081 18.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 ABK71252.1 - 0.045 13.0 0.0 0.059 12.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Phage_holin_4_2 PF04020.13 ABK71253.1 - 1.9e-09 38.1 17.9 2.2e-09 37.9 17.9 1.1 1 0 0 1 1 1 1 Mycobacterial 4 TMS phage holin, superfamily IV Nucleoside_tran PF01733.18 ABK71253.1 - 0.025 14.0 3.4 0.031 13.7 3.4 1.2 1 0 0 1 1 1 0 Nucleoside transporter ABC_membrane_2 PF06472.15 ABK71253.1 - 0.079 12.4 4.7 0.4 10.0 4.7 1.8 1 1 0 1 1 1 0 ABC transporter transmembrane region 2 MFS_1 PF07690.16 ABK71253.1 - 1.7 7.5 21.7 1.8 7.4 21.7 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF21 PF01595.20 ABK71253.1 - 4.3 7.0 14.2 0.12 12.0 5.8 1.9 1 1 1 2 2 2 0 Cyclin M transmembrane N-terminal domain DinB_2 PF12867.7 ABK71254.1 - 8.2e-20 71.6 6.3 1.5e-18 67.5 6.3 2.0 1 1 0 1 1 1 1 DinB superfamily Ribosomal_L32p PF01783.23 ABK71255.1 - 3.4e-14 52.8 2.0 3.9e-14 52.6 2.0 1.0 1 0 0 1 1 1 1 Ribosomal L32p protein family N36 PF11438.8 ABK71255.1 - 0.008 15.9 4.0 0.008 15.9 4.0 1.8 1 1 1 2 2 2 1 36-mer N-terminal peptide of the N protein (N36) RimM PF01782.18 ABK71256.1 - 1.3e-23 83.0 0.5 2.3e-23 82.2 0.5 1.5 1 0 0 1 1 1 1 RimM N-terminal domain PRC PF05239.16 ABK71256.1 - 8.6e-15 54.6 0.2 1.8e-14 53.5 0.2 1.6 1 0 0 1 1 1 1 PRC-barrel domain DUF2171 PF09939.9 ABK71256.1 - 0.0035 17.6 0.2 0.0066 16.7 0.2 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2171) Bac_luciferase PF00296.20 ABK71257.1 - 1.2e-54 185.9 0.0 1.5e-54 185.6 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Asn_synthase PF00733.21 ABK71258.1 - 7.2e-105 351.5 0.2 9e-105 351.2 0.2 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 ABK71258.1 - 8.9e-40 135.4 0.0 1.5e-39 134.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 ABK71258.1 - 3.6e-35 121.1 0.0 7.5e-35 120.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 ABK71258.1 - 0.0026 17.3 0.0 0.0054 16.2 0.0 1.5 1 0 0 1 1 1 1 Aluminium induced protein QueC PF06508.13 ABK71258.1 - 0.0068 15.9 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC NAD_synthase PF02540.17 ABK71258.1 - 0.016 14.4 0.0 0.03 13.5 0.0 1.4 1 0 0 1 1 1 0 NAD synthase FCD PF07729.12 ABK71259.1 - 2.3e-20 73.3 9.2 3.7e-20 72.6 9.2 1.4 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 ABK71259.1 - 1.8e-10 40.3 0.3 4.3e-10 39.1 0.3 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Rrf2 PF02082.20 ABK71259.1 - 0.0098 16.2 0.0 0.019 15.3 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator MarR_2 PF12802.7 ABK71259.1 - 0.034 14.0 0.2 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 MarR family TrmB PF01978.19 ABK71259.1 - 0.16 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF2157 PF09925.9 ABK71260.1 - 0.0011 18.8 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2157) Sugar_tr PF00083.24 ABK71261.1 - 1.4e-59 202.2 19.5 1.8e-59 201.8 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ABK71261.1 - 4.3e-32 111.4 63.8 1.7e-26 93.0 36.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ABK71261.1 - 8.2e-07 28.6 13.7 8.2e-07 28.6 13.7 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 ABK71261.1 - 0.0015 17.0 6.5 0.0015 17.0 6.5 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 ABK71261.1 - 0.0082 15.0 17.5 0.14 11.0 5.2 2.6 2 1 0 2 2 2 2 MFS_1 like family DUF4328 PF14219.6 ABK71262.1 - 1.6e-28 99.4 16.1 1.6e-28 99.4 16.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4328) DUF1345 PF07077.11 ABK71262.1 - 0.0034 17.1 6.4 0.0034 17.1 6.4 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF1345) HypA PF01155.19 ABK71262.1 - 0.032 14.2 0.5 0.069 13.2 0.5 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF3377 PF11857.8 ABK71262.1 - 0.053 13.5 0.1 3.6 7.6 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) Zn-ribbon_8 PF09723.10 ABK71262.1 - 0.1 12.7 0.5 0.19 11.9 0.5 1.4 1 0 0 1 1 1 0 Zinc ribbon domain DZR PF12773.7 ABK71262.1 - 0.13 12.3 0.6 0.22 11.6 0.6 1.3 1 0 0 1 1 1 0 Double zinc ribbon Nudix_N_2 PF14803.6 ABK71262.1 - 0.24 11.4 5.5 0.77 9.7 5.5 1.9 1 1 0 1 1 1 0 Nudix N-terminal Stevor PF17410.2 ABK71262.1 - 0.68 9.4 1.6 1.1 8.7 1.6 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame zf-ribbon_3 PF13248.6 ABK71262.1 - 0.84 9.1 2.6 3.1 7.3 2.4 1.9 1 1 1 2 2 2 0 zinc-ribbon domain Colicin_V PF02674.16 ABK71262.1 - 1.6 8.7 16.4 0.3 11.1 5.9 2.2 2 0 0 2 2 2 0 Colicin V production protein UPF0547 PF10571.9 ABK71262.1 - 1.9 8.6 4.0 1.7 8.8 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 YqhR PF11085.8 ABK71262.1 - 4 7.4 8.3 0.88 9.5 1.1 2.2 2 0 0 2 2 2 0 Conserved membrane protein YqhR BPD_transp_2 PF02653.16 ABK71263.1 - 1.5e-45 155.5 53.4 1.4e-44 152.3 51.2 2.4 2 1 0 2 2 2 1 Branched-chain amino acid transport system / permease component SLATT_4 PF18186.1 ABK71263.1 - 0.27 10.8 0.0 1.1 8.9 0.0 2.0 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 SnoaL_2 PF12680.7 ABK71264.1 - 4e-14 53.1 0.3 4.9e-14 52.8 0.3 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 ABK71264.1 - 0.00017 21.9 0.1 0.00022 21.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_4 PF13577.6 ABK71264.1 - 0.00059 20.0 0.0 0.00072 19.7 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 ABK71264.1 - 0.0072 16.1 0.0 3.3 7.5 0.0 2.1 2 0 0 2 2 2 2 SnoaL-like polyketide cyclase LEH PF07858.12 ABK71264.1 - 0.12 12.5 0.0 0.19 11.9 0.0 1.3 1 1 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain CaMKII_AD PF08332.10 ABK71264.1 - 0.22 11.7 0.0 0.6 10.3 0.0 1.6 1 1 1 2 2 2 0 Calcium/calmodulin dependent protein kinase II association domain HATPase_c PF02518.26 ABK71265.1 - 5.3e-19 68.8 0.0 9.3e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ABK71265.1 - 6.3e-10 39.0 0.7 1.7e-09 37.6 0.7 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 ABK71265.1 - 1.3e-05 25.1 0.0 3.4e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 ABK71265.1 - 0.0037 17.1 0.0 0.0066 16.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LrgB PF04172.16 ABK71265.1 - 0.035 13.6 0.1 0.035 13.6 0.1 2.3 3 0 0 3 3 3 0 LrgB-like family HAMP PF00672.25 ABK71265.1 - 0.042 14.2 1.4 0.93 9.9 0.3 3.0 2 0 0 2 2 2 0 HAMP domain LZ_Tnp_IS481 PF13011.6 ABK71266.1 - 0.14 12.7 0.3 0.37 11.4 0.3 1.7 1 1 0 1 1 1 0 leucine-zipper of insertion element IS481 OB_aCoA_assoc PF01796.17 ABK71267.1 - 4.1e-19 68.3 0.3 7.3e-19 67.5 0.3 1.4 1 0 0 1 1 1 1 DUF35 OB-fold domain, acyl-CoA-associated DUF35_N PF12172.8 ABK71267.1 - 9.5e-09 35.0 0.0 1.5e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) Mago-bind PF09282.10 ABK71268.1 - 0.069 13.0 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Mago binding DMRL_synthase PF00885.19 ABK71269.1 - 1.3e-37 128.8 0.1 1.4e-37 128.6 0.1 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase DUF2510 PF10708.9 ABK71270.1 - 1.6e-12 47.0 13.5 4.6e-12 45.5 13.5 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2510) DUF2897 PF11446.8 ABK71270.1 - 0.21 11.5 1.1 7.9 6.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) FHIPEP PF00771.20 ABK71270.1 - 0.27 9.7 0.0 0.34 9.3 0.0 1.0 1 0 0 1 1 1 0 FHIPEP family VirB3 PF05101.13 ABK71270.1 - 0.27 11.5 3.1 0.43 10.8 0.1 2.2 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein DUF4234 PF14018.6 ABK71270.1 - 0.45 10.7 3.3 0.86 9.8 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) RseC_MucC PF04246.12 ABK71270.1 - 0.92 9.5 2.7 0.42 10.6 0.1 1.6 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Phage_holin_3_6 PF07332.11 ABK71270.1 - 3.7 7.6 14.2 73 3.5 14.2 2.1 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III CopC PF04234.12 ABK71271.1 - 1.8e-24 86.6 0.3 2.5e-24 86.2 0.3 1.2 1 0 0 1 1 1 1 CopC domain Big_5 PF13205.6 ABK71271.1 - 0.0005 20.7 0.3 0.00085 20.0 0.3 1.3 1 0 0 1 1 1 1 Bacterial Ig-like domain DUF5345 PF17280.2 ABK71271.1 - 0.5 10.4 2.2 21 5.2 0.3 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5345) ATP-synt_J PF04911.12 ABK71271.1 - 2.3 7.9 4.2 2.2 8.0 1.2 2.2 2 0 0 2 2 2 0 ATP synthase j chain FAA_hydrolase PF01557.18 ABK71272.1 - 1.4e-63 214.5 0.0 1.7e-63 214.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family SIMPL PF04402.14 ABK71273.1 - 3.4e-26 93.0 0.0 3.8e-26 92.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) AAA_22 PF13401.6 ABK71274.1 - 2.9e-08 34.1 0.1 2.5e-07 31.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 ABK71274.1 - 0.00021 21.7 0.0 0.00091 19.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ABK71274.1 - 0.0016 18.4 0.0 0.051 13.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ABK71274.1 - 0.0019 18.6 0.0 0.0019 18.6 0.0 4.0 3 2 1 4 4 4 2 AAA ATPase domain TPR_10 PF13374.6 ABK71274.1 - 0.002 17.9 14.6 3.1 7.8 0.2 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 ABK71274.1 - 0.012 16.1 1.6 0.012 16.1 1.6 5.7 6 2 2 8 8 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 ABK71274.1 - 0.018 15.6 0.8 0.018 15.6 0.8 10.4 9 1 2 11 11 10 0 Tetratricopeptide repeat TPR_14 PF13428.6 ABK71274.1 - 0.023 15.5 54.4 0.14 13.0 0.1 10.7 6 3 5 11 11 11 0 Tetratricopeptide repeat IstB_IS21 PF01695.17 ABK71274.1 - 0.068 12.9 0.1 0.28 10.9 0.1 2.1 1 1 0 1 1 1 0 IstB-like ATP binding protein TPR_1 PF00515.28 ABK71274.1 - 0.093 12.6 0.4 68 3.5 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_24 PF13479.6 ABK71274.1 - 0.26 11.0 0.0 0.44 10.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain TPR_2 PF07719.17 ABK71274.1 - 0.47 10.7 15.0 7.1 7.0 0.0 6.3 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 ABK71274.1 - 4.4 7.7 30.3 5.1 7.5 0.0 7.1 6 3 2 8 8 8 0 Tetratricopeptide repeat Aldedh PF00171.22 ABK71275.1 - 2.5e-147 491.1 1.0 3e-147 490.9 1.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 ABK71275.1 - 0.0019 17.3 0.0 0.0028 16.8 0.0 1.1 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Peptidase_M24 PF00557.24 ABK71276.1 - 4.7e-53 180.0 1.2 5.4e-53 179.8 1.2 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 CBM39 PF15886.5 ABK71276.1 - 0.059 13.3 0.2 0.51 10.3 0.0 2.1 2 0 0 2 2 2 0 Carbohydrate binding domain (family 32) PTS_EIIA_1 PF00358.20 ABK71277.1 - 5.9e-41 139.2 1.6 8.4e-41 138.7 1.6 1.2 1 0 0 1 1 1 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Biotin_lipoyl_2 PF13533.6 ABK71277.1 - 0.068 13.0 0.7 0.38 10.6 0.1 2.3 2 0 0 2 2 2 0 Biotin-lipoyl like RnfC_N PF13375.6 ABK71277.1 - 0.11 12.4 2.3 3.7 7.6 0.2 3.2 2 1 2 4 4 4 0 RnfC Barrel sandwich hybrid domain Acetyltransf_3 PF13302.7 ABK71280.1 - 4.2e-15 56.6 0.0 5.6e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ABK71280.1 - 2.8e-11 43.8 0.0 4.1e-11 43.3 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ABK71280.1 - 1.1e-08 35.3 0.0 1.6e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 ABK71280.1 - 0.0026 17.4 0.0 0.01 15.5 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ABK71280.1 - 0.14 12.2 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein PALP PF00291.25 ABK71282.1 - 3.4e-80 269.6 3.9 4.2e-80 269.3 3.9 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CoA_binding_2 PF13380.6 ABK71282.1 - 0.073 13.6 0.8 0.99 9.9 0.1 2.5 1 1 1 2 2 2 0 CoA binding domain GAF PF01590.26 ABK71283.1 - 4.3e-07 30.6 0.1 1.1e-06 29.4 0.1 1.7 1 0 0 1 1 1 1 GAF domain Sugar_tr PF00083.24 ABK71284.1 - 7.1e-37 127.3 26.8 5.6e-27 94.7 7.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ABK71284.1 - 7.8e-28 97.4 53.9 6.2e-19 68.1 29.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fe-ADH PF00465.19 ABK71285.1 - 2.8e-109 365.3 2.4 3.1e-109 365.1 2.4 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 ABK71285.1 - 1.3e-15 57.8 0.0 1.1e-12 48.2 0.0 2.1 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase HATPase_c_2 PF13581.6 ABK71286.1 - 2.7e-05 24.1 0.4 4.7e-05 23.3 0.4 1.5 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain DUF4267 PF14087.6 ABK71288.1 - 1.1e-22 80.2 13.7 1.3e-22 79.9 13.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Abhydrolase_3 PF07859.13 ABK71289.1 - 1.7e-45 155.5 0.1 2.3e-45 155.0 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ABK71289.1 - 1.3e-11 44.4 0.0 1.9e-11 43.9 0.0 1.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 ABK71289.1 - 6.6e-05 22.0 0.0 0.00026 20.0 0.0 1.7 2 0 0 2 2 2 1 Carboxylesterase family DLH PF01738.18 ABK71289.1 - 0.011 15.3 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Hydrolase_4 PF12146.8 ABK71289.1 - 0.13 11.5 0.0 1.3 8.2 0.0 2.0 1 1 0 2 2 2 0 Serine aminopeptidase, S33 Cutinase PF01083.22 ABK71289.1 - 0.15 12.0 0.0 0.4 10.6 0.0 1.6 2 0 0 2 2 2 0 Cutinase DUF3018 PF11455.8 ABK71290.1 - 4.8e-28 96.9 5.4 5.2e-28 96.8 5.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3018) CPSase_L_D2 PF02786.17 ABK71291.1 - 4e-81 271.5 0.0 6.1e-81 270.9 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ABK71291.1 - 1.1e-43 148.2 0.2 3.5e-43 146.6 0.1 1.9 2 0 0 2 2 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ABK71291.1 - 3.3e-36 123.7 0.0 1e-35 122.0 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 ABK71291.1 - 1.4e-18 66.5 4.8 4.7e-18 64.8 4.8 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 ABK71291.1 - 2.6e-10 40.2 0.0 6e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 ABK71291.1 - 7.2e-10 38.5 2.6 6.8e-06 25.8 0.4 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 ABK71291.1 - 1.1e-05 25.1 0.0 3e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD_3 PF13437.6 ABK71291.1 - 0.00031 21.4 5.7 0.081 13.6 0.3 3.3 3 0 0 3 3 3 2 HlyD family secretion protein HlyD_D23 PF16576.5 ABK71291.1 - 0.0017 17.6 3.1 0.18 11.0 0.3 2.3 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion Peptidase_M23 PF01551.22 ABK71291.1 - 0.0021 18.2 2.6 0.02 15.1 2.5 2.6 2 0 0 2 2 2 1 Peptidase family M23 ATP-grasp_3 PF02655.14 ABK71291.1 - 0.012 15.6 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain GCV_H PF01597.19 ABK71291.1 - 0.17 11.8 0.7 0.38 10.7 0.7 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein LAL_C2 PF18603.1 ABK71291.1 - 0.32 11.2 4.5 0.34 11.1 0.1 3.2 4 0 0 4 4 4 0 L-amino acid ligase C-terminal domain 2 Epimerase PF01370.21 ABK71292.1 - 4.6e-22 78.7 0.0 8.2e-22 77.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ABK71292.1 - 1.4e-19 70.2 0.0 1.8e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 ABK71292.1 - 2.7e-13 50.2 0.2 5.9e-13 49.1 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 ABK71292.1 - 3.1e-12 46.2 0.0 1.8e-06 27.3 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 ABK71292.1 - 5.8e-12 45.7 0.0 1.6e-11 44.2 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 ABK71292.1 - 6.6e-06 25.9 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 ABK71292.1 - 0.0099 15.0 0.0 0.031 13.4 0.0 1.8 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 ABK71292.1 - 0.15 11.2 0.0 0.4 9.7 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain SpoU_methylase PF00588.19 ABK71293.1 - 2.3e-29 102.4 0.0 2.9e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family LysR_substrate PF03466.20 ABK71294.1 - 2.2e-32 112.1 6.9 2.2e-32 112.1 6.9 1.5 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 ABK71294.1 - 4e-20 71.5 1.8 4e-20 71.5 1.8 2.3 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_5 PF01022.20 ABK71294.1 - 0.0064 16.3 0.1 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 ABK71294.1 - 0.0066 16.5 1.2 0.0066 16.5 1.2 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain Abhydrolase_3 PF07859.13 ABK71295.1 - 3.1e-66 223.3 1.7 3.8e-66 223.0 1.7 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ABK71295.1 - 3.9e-11 42.5 0.9 2.5e-10 39.8 0.9 1.8 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 ABK71295.1 - 3.3e-05 23.5 0.9 0.0028 17.2 1.0 2.7 2 1 0 2 2 2 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 ABK71295.1 - 0.00019 20.5 0.0 0.00026 20.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Esterase_phd PF10503.9 ABK71295.1 - 0.0006 19.4 2.3 0.00071 19.1 0.7 1.9 3 0 0 3 3 3 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 ABK71295.1 - 0.00092 18.5 1.1 1.5 8.0 0.0 2.7 2 1 0 2 2 2 2 Serine aminopeptidase, S33 AXE1 PF05448.12 ABK71295.1 - 0.0012 17.6 0.9 0.0065 15.2 0.4 1.9 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) DLH PF01738.18 ABK71295.1 - 0.0037 16.9 0.0 0.064 12.8 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 ABK71295.1 - 0.0053 17.4 19.7 0.0053 17.4 19.7 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 ABK71295.1 - 0.058 12.2 0.0 0.11 11.3 0.0 1.4 1 1 0 1 1 1 0 Steryl acetyl hydrolase Esterase PF00756.20 ABK71295.1 - 0.06 13.0 0.2 0.32 10.6 0.2 1.9 1 1 0 1 1 1 0 Putative esterase Thioesterase PF00975.20 ABK71295.1 - 0.17 12.0 0.7 0.29 11.2 0.7 1.3 1 0 0 1 1 1 0 Thioesterase domain AMP-binding PF00501.28 ABK71296.1 - 7.6e-28 97.3 0.0 8.2e-28 97.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Peptidase_S8 PF00082.22 ABK71297.1 - 3.8e-36 124.9 2.9 8.7e-36 123.7 2.9 1.6 1 1 0 1 1 1 1 Subtilase family Ribosomal_L22 PF00237.19 ABK71298.1 - 4e-32 110.5 0.4 6.3e-32 109.9 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_60s PF00428.19 ABK71298.1 - 0.032 14.8 11.1 0.69 10.5 1.9 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein GST_C_2 PF13410.6 ABK71299.1 - 1.2e-11 44.5 0.5 2.6e-11 43.4 0.5 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ABK71299.1 - 2e-10 40.8 0.1 2.1e-09 37.5 0.1 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ABK71299.1 - 5e-05 23.4 0.0 9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ABK71299.1 - 0.002 18.3 0.0 0.0031 17.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 ABK71299.1 - 0.0047 16.7 0.0 0.0082 15.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain AA_permease_2 PF13520.6 ABK71300.1 - 2.6e-42 145.2 46.2 3.3e-42 144.8 46.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ABK71300.1 - 3.3e-31 108.4 38.1 4.9e-31 107.9 38.1 1.2 1 0 0 1 1 1 1 Amino acid permease GTP_EFTU PF00009.27 ABK71301.1 - 2e-34 118.8 3.2 5.6e-33 114.1 2.2 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 ABK71301.1 - 1.7e-33 114.8 2.0 3.2e-33 114.0 0.9 2.1 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 ABK71301.1 - 4.7e-10 39.7 2.3 3.1e-05 24.3 0.2 3.1 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ABK71301.1 - 8.2e-09 35.5 0.1 2.1e-08 34.3 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 ABK71301.1 - 1.3e-07 31.4 0.0 2.6e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Ras family IF2_N PF04760.15 ABK71301.1 - 3e-07 30.1 0.0 6.7e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Roc PF08477.13 ABK71301.1 - 0.00063 20.0 0.0 0.0011 19.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 ABK71301.1 - 0.0056 16.1 0.0 0.028 13.9 0.0 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Flagellin_IN PF07196.13 ABK71301.1 - 0.0099 16.1 0.1 13 6.1 0.0 3.3 2 0 0 2 2 2 2 Flagellin hook IN motif FeoB_N PF02421.18 ABK71301.1 - 0.019 14.5 0.1 0.066 12.7 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B NAD_binding_2 PF03446.15 ABK71302.1 - 1.2e-37 129.5 1.0 1.2e-37 129.5 1.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ABK71302.1 - 7.6e-14 52.0 1.6 1.4e-13 51.2 1.6 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 ABK71302.1 - 3.6e-11 43.5 0.3 1.2e-10 41.8 0.2 2.0 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 ABK71302.1 - 1.1e-08 34.7 0.7 1.9e-08 33.9 0.1 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 ABK71302.1 - 0.00019 21.7 0.4 0.00094 19.4 0.4 2.1 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 ABK71302.1 - 0.00024 21.2 0.1 0.00039 20.5 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 ABK71302.1 - 0.00036 20.5 0.9 0.028 14.3 0.2 2.4 1 1 1 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh PF00984.19 ABK71302.1 - 0.00055 20.1 0.0 0.0016 18.6 0.0 1.8 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain IlvN PF07991.12 ABK71302.1 - 0.00062 19.4 0.0 0.00099 18.7 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 ABK71302.1 - 0.0018 17.9 1.9 0.0031 17.2 0.9 2.0 2 1 0 2 2 2 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 ABK71302.1 - 0.0086 15.7 0.4 1.5 8.4 0.0 2.5 1 1 1 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DapB_N PF01113.20 ABK71302.1 - 0.011 15.9 1.9 0.015 15.4 0.6 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 ABK71302.1 - 0.012 16.4 0.1 0.025 15.4 0.1 1.5 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Rossmann-like PF10727.9 ABK71302.1 - 0.015 15.2 4.3 0.015 15.2 4.3 2.1 2 1 0 2 2 2 0 Rossmann-like domain NmrA PF05368.13 ABK71302.1 - 0.016 14.8 0.6 0.026 14.1 0.6 1.4 1 0 0 1 1 1 0 NmrA-like family RTC_insert PF05189.13 ABK71302.1 - 0.045 14.3 0.2 0.097 13.2 0.2 1.5 1 0 0 1 1 1 0 RNA 3'-terminal phosphate cyclase (RTC), insert domain LpxI_N PF17930.1 ABK71302.1 - 0.046 13.6 0.7 2.5 8.0 0.1 2.6 1 1 1 2 2 2 0 LpxI N-terminal domain HTH_AsnC-type PF13404.6 ABK71302.1 - 0.052 13.4 0.7 3.5 7.5 0.1 2.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain ADH_zinc_N PF00107.26 ABK71302.1 - 1.4 8.9 9.5 1.7 8.7 5.1 2.8 2 2 0 2 2 2 0 Zinc-binding dehydrogenase MarR PF01047.22 ABK71303.1 - 4.2e-13 49.0 0.4 2e-12 46.8 0.4 2.0 1 1 0 1 1 1 1 MarR family MarR_2 PF12802.7 ABK71303.1 - 2.9e-11 43.1 0.2 9.1e-11 41.5 0.2 1.9 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 ABK71303.1 - 1.8e-09 37.9 0.4 1.3e-07 32.0 0.2 2.5 2 1 1 3 3 2 1 Winged helix DNA-binding domain HTH_20 PF12840.7 ABK71303.1 - 2.5e-05 24.2 1.3 5.6e-05 23.1 0.2 2.1 2 1 0 2 2 2 1 Helix-turn-helix domain DprA_WH PF17782.1 ABK71303.1 - 0.00016 21.8 2.1 0.0011 19.1 0.1 2.6 3 0 0 3 3 3 1 DprA winged helix domain HTH_Crp_2 PF13545.6 ABK71303.1 - 0.00018 21.4 0.1 0.00037 20.4 0.1 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_34 PF13601.6 ABK71303.1 - 0.00083 19.5 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_5 PF01022.20 ABK71303.1 - 0.0011 18.7 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_IclR PF09339.10 ABK71303.1 - 0.0015 18.3 0.2 0.0036 17.1 0.2 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain Fe_dep_repress PF01325.19 ABK71303.1 - 0.0034 17.6 0.1 0.0081 16.3 0.0 1.6 2 0 0 2 2 1 1 Iron dependent repressor, N-terminal DNA binding domain GntR PF00392.21 ABK71303.1 - 0.01 15.5 0.4 0.038 13.6 0.1 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_36 PF13730.6 ABK71303.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain LexA_DNA_bind PF01726.16 ABK71303.1 - 0.014 15.2 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 LexA DNA binding domain HTH_24 PF13412.6 ABK71303.1 - 0.021 14.4 0.0 0.044 13.3 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding PadR PF03551.14 ABK71303.1 - 0.023 14.6 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family TrmB PF01978.19 ABK71303.1 - 0.04 13.8 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 1 0 Sugar-specific transcriptional regulator TrmB DUF4423 PF14394.6 ABK71303.1 - 0.043 13.5 0.0 0.085 12.6 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4423) Replic_Relax PF13814.6 ABK71303.1 - 0.048 13.7 0.1 0.063 13.3 0.1 1.3 1 0 0 1 1 1 0 Replication-relaxation Rrf2 PF02082.20 ABK71303.1 - 0.056 13.8 0.0 0.16 12.3 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator Cdc6_C PF09079.11 ABK71303.1 - 0.057 13.4 0.2 0.54 10.3 0.1 2.5 2 1 1 3 3 3 0 CDC6, C terminal winged helix domain FeoC PF09012.10 ABK71303.1 - 0.057 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 FeoC like transcriptional regulator RNA_pol_Rpc34 PF05158.12 ABK71303.1 - 0.073 12.4 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit AAA_assoc_C PF09821.9 ABK71303.1 - 0.093 13.3 0.1 0.17 12.4 0.1 1.5 1 1 0 1 1 1 0 C-terminal AAA-associated domain Penicillinase_R PF03965.16 ABK71303.1 - 0.095 13.1 0.1 0.23 11.8 0.0 1.6 2 0 0 2 2 2 0 Penicillinase repressor HemN_C PF06969.16 ABK71303.1 - 0.11 12.6 0.0 2.1 8.5 0.0 2.6 2 1 0 2 2 2 0 HemN C-terminal domain HxlR PF01638.17 ABK71303.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.5 1 1 0 1 1 1 0 HxlR-like helix-turn-helix Methyltr_RsmB-F PF01189.17 ABK71304.1 - 3.2e-56 190.2 0.0 4.6e-56 189.6 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F NusB PF01029.18 ABK71304.1 - 4.9e-28 98.0 0.0 7.4e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 NusB family Methyltransf_25 PF13649.6 ABK71304.1 - 0.0034 18.1 0.1 0.023 15.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABK71304.1 - 0.028 15.0 0.1 0.23 12.2 0.1 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 ABK71304.1 - 0.21 11.2 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Sigma70_r3 PF04539.16 ABK71305.1 - 1.7e-28 98.5 0.9 1.7e-28 98.5 0.9 3.9 5 0 0 5 5 5 1 Sigma-70 region 3 Sigma70_r2 PF04542.14 ABK71305.1 - 7.1e-23 80.2 0.4 1.8e-22 78.9 0.3 1.7 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 ABK71305.1 - 1.2e-20 72.7 4.1 2.6e-18 65.2 0.7 2.9 2 0 0 2 2 2 2 Sigma-70, region 4 Sigma70_r1_2 PF00140.20 ABK71305.1 - 4.5e-16 58.6 0.4 4.5e-16 58.6 0.4 3.0 2 0 0 2 2 2 1 Sigma-70 factor, region 1.2 HTH_15 PF12324.8 ABK71305.1 - 0.1 12.5 1.8 0.56 10.2 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain of alkylmercury lyase DUF4185 PF13810.6 ABK71306.1 - 1.7e-117 392.1 2.0 2e-117 391.9 2.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) FAM75 PF14650.6 ABK71306.1 - 2.3 7.7 13.5 3.2 7.2 13.5 1.1 1 0 0 1 1 1 0 FAM75 family Sulfatase PF00884.23 ABK71307.1 - 7.3e-57 193.1 0.0 8.9e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 ABK71307.1 - 0.00024 21.3 0.1 0.00024 21.3 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 ABK71307.1 - 0.006 16.2 0.2 0.11 12.1 0.1 2.2 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase CitF PF04223.12 ABK71307.1 - 0.28 10.0 0.0 0.39 9.5 0.0 1.1 1 0 0 1 1 1 0 Citrate lyase, alpha subunit (CitF) 2Fe-2S_thioredx PF01257.19 ABK71308.1 - 1.8e-51 173.8 0.0 2.2e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin SepF PF04472.12 ABK71309.1 - 1.7e-24 85.9 0.0 2.5e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Cell division protein SepF PEP_mutase PF13714.6 ABK71310.1 - 3.1e-63 213.4 0.7 3.8e-63 213.1 0.7 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase TMP-TENI PF02581.17 ABK71310.1 - 0.064 12.6 0.0 0.22 10.9 0.0 1.9 1 1 0 1 1 1 0 Thiamine monophosphate synthase Pantoate_transf PF02548.15 ABK71310.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.6 1 1 0 1 1 1 0 Ketopantoate hydroxymethyltransferase tRNA-synt_1g PF09334.11 ABK71311.1 - 3e-108 362.1 0.0 2.4e-106 355.8 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 ABK71311.1 - 1.5e-28 99.5 0.3 5.6e-15 54.6 0.0 3.8 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 ABK71311.1 - 1.5e-13 50.8 0.0 6.6e-07 29.0 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 ABK71311.1 - 2e-05 24.6 0.4 6.2e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1f PF01921.18 ABK71311.1 - 0.00022 20.3 0.0 0.19 10.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (K) DUF3533 PF12051.8 ABK71312.1 - 3.1e-05 23.1 1.5 3.1e-05 23.1 1.5 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3533) Big_3_5 PF16640.5 ABK71312.1 - 0.12 12.6 1.4 6.8 7.0 0.1 2.8 2 1 0 2 2 2 0 Bacterial Ig-like domain (group 3) DUF218 PF02698.17 ABK71313.1 - 7.8e-07 29.2 0.0 1e-06 28.8 0.0 1.1 1 0 0 1 1 1 1 DUF218 domain HSP20 PF00011.21 ABK71314.1 - 1.1e-22 80.1 0.0 1.7e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ABK71314.1 - 1.9e-13 49.8 0.0 4.2e-13 48.6 0.0 1.6 2 0 0 2 2 2 1 HSP20-like domain found in ArsA GvpH PF05455.11 ABK71314.1 - 0.013 15.6 0.3 0.022 14.8 0.3 1.3 1 0 0 1 1 1 0 GvpH Pkinase PF00069.25 ABK71316.1 - 2e-41 142.1 0.0 3.1e-41 141.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ABK71316.1 - 1e-31 110.2 0.0 2.3e-31 109.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase TPR_MalT PF17874.1 ABK71316.1 - 1.4e-14 54.2 7.5 1.4e-14 54.2 7.5 2.4 2 0 0 2 2 2 1 MalT-like TPR region AAA_16 PF13191.6 ABK71316.1 - 6e-11 43.0 4.2 7.6e-11 42.7 0.3 2.9 3 0 0 3 3 2 1 AAA ATPase domain AAA_22 PF13401.6 ABK71316.1 - 6.7e-08 32.9 0.0 2.1e-07 31.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain TPR_12 PF13424.6 ABK71316.1 - 2.9e-05 24.3 1.1 2.9e-05 24.3 1.1 4.8 6 0 0 6 6 5 1 Tetratricopeptide repeat NB-ARC PF00931.22 ABK71316.1 - 4.1e-05 22.9 0.2 7.4e-05 22.1 0.2 1.3 1 0 0 1 1 1 1 NB-ARC domain IstB_IS21 PF01695.17 ABK71316.1 - 0.00014 21.7 0.1 0.00054 19.7 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.6 ABK71316.1 - 0.00017 21.6 0.0 0.00076 19.5 0.0 2.1 2 1 0 2 2 1 1 AAA domain AAA_25 PF13481.6 ABK71316.1 - 0.0002 21.0 2.1 0.00043 19.9 0.3 2.4 3 0 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 ABK71316.1 - 0.00062 19.7 0.0 0.001 19.0 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_33 PF13671.6 ABK71316.1 - 0.0036 17.5 0.1 0.012 15.8 0.0 2.0 2 0 0 2 2 1 1 AAA domain TPR_2 PF07719.17 ABK71316.1 - 0.0041 17.1 4.3 0.07 13.3 0.2 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_23 PF13476.6 ABK71316.1 - 0.0069 16.9 0.0 0.013 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain TPR_19 PF14559.6 ABK71316.1 - 0.0083 16.6 17.8 0.14 12.7 0.2 4.6 4 1 0 4 4 3 1 Tetratricopeptide repeat NACHT PF05729.12 ABK71316.1 - 0.015 15.2 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain TPR_16 PF13432.6 ABK71316.1 - 0.021 15.5 0.5 0.021 15.5 0.5 5.3 6 0 0 6 6 3 0 Tetratricopeptide repeat DUF2075 PF09848.9 ABK71316.1 - 0.029 13.6 0.0 0.043 13.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CbiA PF01656.23 ABK71316.1 - 0.036 14.1 0.0 0.13 12.4 0.0 2.1 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATPase PF06745.13 ABK71316.1 - 0.038 13.3 0.0 0.087 12.1 0.0 1.6 1 0 0 1 1 1 0 KaiC RsgA_GTPase PF03193.16 ABK71316.1 - 0.05 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase ParA PF10609.9 ABK71316.1 - 0.052 13.0 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase PhoH PF02562.16 ABK71316.1 - 0.066 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.6 ABK71316.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain TPR_4 PF07721.14 ABK71316.1 - 0.25 12.1 0.1 0.25 12.1 0.1 6.4 6 0 0 6 6 4 0 Tetratricopeptide repeat Topoisom_I PF01028.20 ABK71317.1 - 2.6e-22 79.2 0.0 3.2e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core DUF5419 PF17441.2 ABK71317.1 - 0.1 12.7 0.2 18 5.5 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5419) Bac_luciferase PF00296.20 ABK71318.1 - 1.7e-41 142.7 0.4 2.1e-41 142.4 0.4 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase TauE PF01925.19 ABK71319.1 - 3.8e-43 147.8 34.3 4.3e-43 147.6 34.3 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Glucos_trans_II PF14264.6 ABK71319.1 - 0.49 9.7 8.0 0.8 9.0 1.9 2.5 2 1 0 2 2 2 0 Glucosyl transferase GtrII Peptidase_U4 PF03419.13 ABK71319.1 - 9.5 5.4 12.4 29 3.8 4.4 2.2 1 1 1 2 2 2 0 Sporulation factor SpoIIGA MFS_1 PF07690.16 ABK71320.1 - 5.4e-27 94.6 63.4 3.1e-21 75.7 27.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK71320.1 - 3.5e-06 26.2 28.1 6e-06 25.4 10.4 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 ABK71320.1 - 0.00015 20.5 4.4 0.00015 20.5 4.4 2.6 2 1 1 3 3 3 2 MFS/sugar transport protein TctB PF07331.11 ABK71321.1 - 7e-19 68.4 19.4 9e-19 68.1 19.4 1.1 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family DUF202 PF02656.15 ABK71321.1 - 1.2 9.6 18.3 0.2 12.1 3.8 3.1 2 2 0 2 2 2 0 Domain of unknown function (DUF202) LRR19-TM PF15176.6 ABK71321.1 - 1.6 8.8 2.7 4.3 7.4 0.0 2.7 3 1 1 4 4 4 0 Leucine-rich repeat family 19 TM domain Phage_holin_2_3 PF16080.5 ABK71321.1 - 6.5 6.6 10.0 7.6 6.4 0.5 3.1 2 1 1 3 3 3 0 Bacteriophage holin family HP1 ATP_synt_H PF05493.13 ABK71321.1 - 6.6 7.3 8.6 13 6.4 3.3 2.5 1 1 1 2 2 2 0 ATP synthase subunit H Phage_holin_3_6 PF07332.11 ABK71321.1 - 8.3 6.5 26.7 5.8 7.0 8.4 2.2 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Bac_luciferase PF00296.20 ABK71322.1 - 6.9e-32 111.1 0.5 1.1e-31 110.5 0.5 1.3 1 0 0 1 1 1 1 Luciferase-like monooxygenase Abhydrolase_9 PF10081.9 ABK71323.1 - 1.3e-129 431.3 1.0 1.8e-129 430.9 1.0 1.1 1 0 0 1 1 1 1 Alpha/beta-hydrolase family Abhydrolase_9_N PF15420.6 ABK71323.1 - 2e-68 230.5 13.9 2e-68 230.5 13.9 1.5 2 0 0 2 2 2 1 Alpha/beta-hydrolase family N-terminus PS_pyruv_trans PF04230.13 ABK71324.1 - 2.3e-19 70.4 0.0 3.7e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide pyruvyl transferase PMT_2 PF13231.6 ABK71325.1 - 6.3e-24 85.0 20.3 6.3e-24 85.0 20.3 3.7 3 1 1 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase HTH_32 PF13565.6 ABK71325.1 - 0.0088 16.6 2.2 0.019 15.5 0.2 2.6 2 0 0 2 2 2 1 Homeodomain-like domain adh_short PF00106.25 ABK71326.1 - 1.6e-58 197.4 2.5 1.8e-58 197.2 2.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK71326.1 - 2.5e-44 151.6 4.5 3e-44 151.3 4.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK71326.1 - 2.8e-17 63.2 1.9 4.3e-17 62.6 1.9 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK71326.1 - 5.3e-06 26.1 0.7 7.6e-06 25.6 0.7 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ABK71326.1 - 0.017 14.5 0.1 0.026 14.0 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase ApbA PF02558.16 ABK71326.1 - 0.053 13.2 0.4 0.18 11.5 0.1 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Asp23 PF03780.13 ABK71326.1 - 0.055 13.9 0.1 0.21 12.1 0.1 2.0 1 1 0 1 1 1 0 Asp23 family, cell envelope-related function DUF1776 PF08643.10 ABK71326.1 - 0.1 11.9 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NmrA PF05368.13 ABK71326.1 - 0.14 11.7 2.0 6.3 6.3 2.3 2.1 2 0 0 2 2 2 0 NmrA-like family ECH_1 PF00378.20 ABK71327.1 - 2e-53 181.3 0.2 2.6e-53 180.9 0.2 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK71327.1 - 2.9e-30 105.9 0.1 3.3e-30 105.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase dCMP_cyt_deam_1 PF00383.23 ABK71327.1 - 0.18 11.7 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region Fic PF02661.18 ABK71328.1 - 1.2e-20 74.2 0.2 4.5e-20 72.4 0.0 2.1 2 0 0 2 2 2 1 Fic/DOC family HTH_13 PF11972.8 ABK71328.1 - 9.9e-06 25.5 0.0 2.6e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 HTH DNA binding domain Fic_N PF13784.6 ABK71328.1 - 0.00057 19.9 3.4 0.0016 18.4 3.4 1.8 1 0 0 1 1 1 1 Fic/DOC family N-terminal FtsK_gamma PF09397.10 ABK71328.1 - 0.0023 17.7 0.0 0.0049 16.6 0.0 1.6 1 0 0 1 1 1 1 Ftsk gamma domain HTH_24 PF13412.6 ABK71328.1 - 0.011 15.3 0.0 0.032 13.8 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 ABK71328.1 - 0.06 13.3 0.0 0.3 11.1 0.0 2.2 2 0 0 2 2 2 0 HTH domain MarR_2 PF12802.7 ABK71328.1 - 0.099 12.5 0.1 0.099 12.5 0.1 3.6 5 0 0 5 5 5 0 MarR family Glyco_hydro_1 PF00232.18 ABK71329.1 - 3.6e-162 539.9 0.0 4.1e-162 539.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 DSBA PF01323.20 ABK71330.1 - 5.1e-09 36.2 0.1 0.00014 21.7 0.0 2.0 2 0 0 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_5 PF13743.6 ABK71330.1 - 0.0016 18.2 0.0 0.0021 17.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin adh_short_C2 PF13561.6 ABK71331.1 - 3.2e-41 141.4 9.1 4.5e-41 140.9 9.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK71331.1 - 5.5e-41 140.2 2.6 1.1e-40 139.2 2.6 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK71331.1 - 2.9e-06 27.3 1.0 2.9e-06 27.3 1.0 2.0 2 0 0 2 2 2 1 KR domain CbiJ PF02571.14 ABK71331.1 - 0.00047 19.7 0.5 0.088 12.3 0.1 2.4 2 1 0 2 2 2 1 Precorrin-6x reductase CbiJ/CobK 3HCDH_N PF02737.18 ABK71331.1 - 0.0033 17.3 2.8 0.0042 17.0 0.5 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_transf_4 PF13439.6 ABK71331.1 - 0.0035 17.4 0.3 3.1 7.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Sacchrp_dh_NADP PF03435.18 ABK71331.1 - 0.0036 17.6 3.5 0.019 15.2 0.6 2.4 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 ABK71331.1 - 0.0064 16.1 0.4 0.012 15.2 0.1 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Epimerase PF01370.21 ABK71331.1 - 0.0069 15.9 3.0 0.011 15.3 0.5 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 ABK71331.1 - 0.019 15.4 3.3 0.066 13.6 1.1 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding CoA_binding_2 PF13380.6 ABK71331.1 - 0.032 14.7 3.4 6.3 7.3 0.3 2.6 2 1 0 2 2 2 0 CoA binding domain Amidohydro_2 PF04909.14 ABK71331.1 - 0.1 12.3 2.7 0.076 12.8 0.9 1.6 2 0 0 2 2 2 0 Amidohydrolase DFP PF04127.15 ABK71331.1 - 0.16 11.8 8.6 2.3 8.0 1.6 2.4 2 1 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein THF_DHG_CYH_C PF02882.19 ABK71331.1 - 0.19 11.0 2.6 0.17 11.2 0.4 2.1 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ATPgrasp_N PF18130.1 ABK71331.1 - 0.2 12.2 3.9 4 8.1 0.6 2.6 2 1 0 2 2 2 0 ATP-grasp N-terminal domain LytR_C PF13399.6 ABK71331.1 - 5.9 7.9 10.1 13 6.9 0.9 3.5 1 1 1 2 2 2 0 LytR cell envelope-related transcriptional attenuator AA_permease_2 PF13520.6 ABK71332.1 - 1e-27 97.0 51.2 1.3e-27 96.7 51.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ABK71332.1 - 2.1e-17 62.9 50.7 4.1e-17 61.9 50.7 1.5 1 1 0 1 1 1 1 Amino acid permease TetR_C_6 PF13977.6 ABK71333.1 - 4.9e-27 94.4 2.6 4.9e-27 94.4 2.6 1.8 2 1 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal TetR_N PF00440.23 ABK71333.1 - 2.2e-11 43.3 0.1 4.3e-11 42.4 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family LacI PF00356.21 ABK71333.1 - 0.072 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family Herpes_TK_C PF08465.10 ABK71333.1 - 0.16 11.7 1.4 0.67 9.7 1.4 2.0 1 1 0 1 1 1 0 Thymidine kinase from Herpesvirus C-terminal SBP_bac_6 PF13343.6 ABK71334.1 - 2e-28 99.4 0.6 3.1e-28 98.8 0.6 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 ABK71334.1 - 1.3e-17 64.6 9.2 2.1e-17 63.8 9.2 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 ABK71334.1 - 1.5e-09 38.0 2.9 3.9e-09 36.6 2.4 1.9 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein PapD_C PF02753.17 ABK71334.1 - 0.075 13.4 0.1 0.075 13.4 0.1 2.5 2 0 0 2 2 2 0 Pili assembly chaperone PapD, C-terminal domain SfLAP PF11139.8 ABK71335.1 - 1.7e-55 187.8 23.7 1.9e-55 187.6 23.7 1.0 1 0 0 1 1 1 1 Sap, sulfolipid-1-addressing protein AbrB PF05145.12 ABK71336.1 - 2.7e-78 263.1 49.1 2.7e-78 263.1 49.1 2.0 1 1 1 2 2 2 2 Transition state regulatory protein AbrB Acyl_transf_3 PF01757.22 ABK71336.1 - 0.17 10.9 24.7 0.065 12.3 5.5 2.3 1 1 1 2 2 2 0 Acyltransferase family 2OG-FeII_Oxy PF03171.20 ABK71337.1 - 4.7e-18 65.5 0.0 7.8e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 ABK71337.1 - 9.6e-18 65.1 0.0 1.5e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal BPD_transp_1 PF00528.22 ABK71338.1 - 5e-29 101.3 13.6 5e-29 101.3 13.6 1.9 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 ABK71338.1 - 2.2e-06 27.5 1.0 2.2e-06 27.5 1.0 3.8 4 1 0 4 4 4 1 N-terminal TM domain of oligopeptide transport permease C QRPTase_C PF01729.19 ABK71340.1 - 5.4e-61 205.3 0.4 8.8e-61 204.6 0.0 1.5 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 ABK71340.1 - 4.8e-21 74.6 0.4 1.1e-20 73.5 0.1 1.7 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain VirC1 PF07015.11 ABK71340.1 - 0.06 12.6 0.3 0.095 12.0 0.3 1.3 1 0 0 1 1 1 0 VirC1 protein DUF1153 PF06627.11 ABK71340.1 - 0.06 13.5 0.7 0.49 10.6 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1153) Sua5_yciO_yrdC PF01300.18 ABK71341.1 - 8.8e-44 149.1 0.0 1.3e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination zf-HYPF PF07503.12 ABK71341.1 - 6.8e-34 115.3 13.9 1.4e-17 63.1 3.8 2.5 2 0 0 2 2 2 2 HypF finger HypF_C PF17788.1 ABK71341.1 - 1.6e-27 96.2 0.2 2.7e-27 95.4 0.2 1.4 1 0 0 1 1 1 1 HypF Kae1-like domain Acylphosphatase PF00708.18 ABK71341.1 - 3e-18 66.0 0.0 4.8e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Acylphosphatase Peptidase_M22 PF00814.25 ABK71341.1 - 1.4e-05 24.9 0.0 0.00028 20.7 0.0 2.1 2 0 0 2 2 2 1 Glycoprotease family DZR PF12773.7 ABK71341.1 - 0.0061 16.6 3.7 0.48 10.5 0.2 2.7 2 0 0 2 2 2 2 Double zinc ribbon NMD3 PF04981.13 ABK71341.1 - 0.023 14.2 2.7 0.21 11.0 1.9 2.1 1 1 1 2 2 2 0 NMD3 family Zn-ribbon_8 PF09723.10 ABK71341.1 - 1.3 9.2 6.0 3.2 7.9 1.4 2.9 2 1 1 3 3 3 0 Zinc ribbon domain DNA_RNApol_7kD PF03604.13 ABK71341.1 - 4.1 7.2 9.0 2 8.1 1.7 2.8 2 1 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Ring_hydroxyl_A PF00848.19 ABK71342.1 - 8.9e-50 169.6 0.7 1.4e-49 168.9 0.5 1.4 2 0 0 2 2 2 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 ABK71342.1 - 1.3e-07 31.4 0.0 2.2e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Peptidase_M20 PF01546.28 ABK71343.1 - 3.8e-07 30.0 2.6 6.3e-07 29.3 2.6 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ABK71343.1 - 2.5e-06 27.4 0.1 6.1e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Thioredox_DsbH PF03190.15 ABK71344.1 - 1.8e-68 229.6 0.0 3.1e-68 228.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 ABK71344.1 - 1.5e-10 41.1 0.1 3.2e-10 40.0 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin-like GlcNAc_2-epim PF07221.11 ABK71344.1 - 0.011 15.0 2.6 0.29 10.4 0.0 2.9 3 0 0 3 3 3 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) DUF885 PF05960.11 ABK71345.1 - 5.7e-05 23.0 2.7 0.00011 22.0 1.3 1.9 1 1 0 2 2 2 1 Bacterial protein of unknown function (DUF885) Acyl-CoA_dh_2 PF08028.11 ABK71346.1 - 4.6e-39 133.8 6.5 9e-39 132.8 4.5 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK71346.1 - 3e-06 27.9 0.0 9.3e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ABK71346.1 - 8e-06 26.0 0.0 1.3e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 ABK71346.1 - 0.017 15.3 1.3 0.036 14.3 1.3 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain HTH_20 PF12840.7 ABK71347.1 - 2e-17 63.0 0.7 2e-17 63.0 0.7 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_5 PF01022.20 ABK71347.1 - 6e-13 48.4 1.3 6.1e-13 48.4 0.0 1.7 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 ABK71347.1 - 9.6e-07 28.6 1.4 9.6e-07 28.6 1.4 1.6 2 0 0 2 2 2 1 MarR family Arg_repressor PF01316.21 ABK71347.1 - 3.2e-05 23.6 0.0 4.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Arginine repressor, DNA binding domain HxlR PF01638.17 ABK71347.1 - 0.00012 21.8 0.1 0.0002 21.1 0.1 1.4 1 1 0 1 1 1 1 HxlR-like helix-turn-helix HTH_Crp_2 PF13545.6 ABK71347.1 - 0.0011 18.9 0.4 0.0045 16.9 0.1 1.9 1 1 1 2 2 2 1 Crp-like helix-turn-helix domain TrmB PF01978.19 ABK71347.1 - 0.0064 16.3 0.0 0.0089 15.9 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 ABK71347.1 - 0.0066 16.2 0.7 0.016 15.0 0.7 1.8 1 1 0 1 1 1 1 IclR helix-turn-helix domain VbhA PF18495.1 ABK71347.1 - 0.029 14.2 0.0 0.071 13.0 0.0 1.6 1 0 0 1 1 1 0 Antitoxin VbhA HTH_28 PF13518.6 ABK71347.1 - 0.03 14.4 2.0 2.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_1 PF00126.27 ABK71347.1 - 0.099 12.6 0.6 0.73 9.8 0.0 2.6 3 1 0 3 3 3 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_24 PF13412.6 ABK71347.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR PF01047.22 ABK71347.1 - 0.12 12.3 0.5 0.28 11.1 0.0 1.8 2 0 0 2 2 2 0 MarR family zf-HC2 PF13490.6 ABK71347.1 - 7.5 6.9 7.5 3.4 8.0 0.1 2.9 3 0 0 3 3 3 0 Putative zinc-finger AlaDh_PNT_C PF01262.21 ABK71348.1 - 2.8e-62 209.8 1.0 2.1e-61 206.9 1.6 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 ABK71348.1 - 1.8e-44 151.3 0.1 5.2e-44 149.8 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain 2-Hacid_dh_C PF02826.19 ABK71348.1 - 0.0026 17.1 0.0 0.058 12.8 0.0 2.4 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 ABK71348.1 - 0.02 15.0 0.2 0.074 13.2 0.2 1.8 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_zinc_N PF00107.26 ABK71348.1 - 0.12 12.4 1.1 0.19 11.7 0.2 1.8 2 1 0 2 2 2 0 Zinc-binding dehydrogenase Rieske PF00355.26 ABK71349.1 - 2.3e-11 43.5 0.0 8.5e-11 41.7 0.0 1.8 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 ABK71349.1 - 3.6e-10 39.7 0.0 8.4e-09 35.3 0.0 2.0 1 1 0 1 1 1 1 Rieske-like [2Fe-2S] domain SnoaL_4 PF13577.6 ABK71350.1 - 0.0017 18.5 0.0 0.0021 18.2 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SSF PF00474.17 ABK71351.1 - 1.2e-31 110.1 36.3 1.6e-31 109.6 36.3 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family YjgF_endoribonc PF14588.6 ABK71352.1 - 1.7e-27 96.4 0.2 1.9e-27 96.2 0.2 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 ABK71352.1 - 3.5e-22 78.7 0.3 4.5e-22 78.3 0.3 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP YCII PF03795.14 ABK71353.1 - 1.8e-09 37.9 0.0 2.2e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain IF3_C PF00707.22 ABK71354.1 - 1.6e-32 111.3 0.1 2.4e-32 110.7 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 ABK71354.1 - 1.6e-30 105.2 0.1 3e-30 104.3 0.1 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain DUF3445 PF11927.8 ABK71355.1 - 4.1e-53 180.3 0.0 5.2e-53 180.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) PALP PF00291.25 ABK71355.1 - 0.09 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Iso_dh PF00180.20 ABK71356.1 - 2.7e-85 286.6 0.0 3.3e-85 286.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DHHW PF14286.6 ABK71356.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 DHHW protein Glyco_transf_4 PF13439.6 ABK71357.1 - 4.2e-25 88.7 6.1 4.2e-25 88.7 6.1 1.7 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 ABK71357.1 - 1.1e-21 77.2 0.0 1.7e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 ABK71357.1 - 9.4e-20 71.7 13.7 9.4e-20 71.7 13.7 2.6 1 1 1 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 ABK71357.1 - 3e-19 69.8 0.9 9.9e-19 68.1 0.4 2.2 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 ABK71357.1 - 4.4e-08 33.3 0.0 8.5e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 ABK71357.1 - 1.7e-05 25.1 0.0 3.6e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Lactamase_B PF00753.27 ABK71358.1 - 2.2e-24 86.6 5.7 3.2e-24 86.1 5.7 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ABK71358.1 - 8.3e-06 25.5 0.5 1.4e-05 24.7 0.5 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain TPP_enzyme_N PF02776.18 ABK71359.1 - 5.6e-34 117.2 1.4 5.6e-34 117.2 1.4 3.1 3 1 0 3 3 3 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 ABK71359.1 - 4.2e-30 104.6 7.5 1.5e-29 102.8 0.1 3.8 5 0 0 5 5 5 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Peripla_BP_6 PF13458.6 ABK71360.1 - 1.2e-47 163.3 12.4 1.4e-47 163.0 12.4 1.0 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 ABK71360.1 - 3e-13 49.6 0.0 4.2e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_5 PF13433.6 ABK71360.1 - 1.1e-11 44.3 0.1 7e-11 41.7 0.1 2.0 1 1 0 1 1 1 1 Periplasmic binding protein domain DUF1731 PF08338.11 ABK71361.1 - 6.2e-16 58.0 0.4 6.2e-16 58.0 0.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1731) Epimerase PF01370.21 ABK71361.1 - 7.7e-12 45.2 0.0 1e-10 41.5 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ABK71361.1 - 0.00044 20.2 0.1 0.0011 18.9 0.1 1.7 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 ABK71361.1 - 0.0026 17.2 0.0 0.79 9.1 0.0 2.5 2 1 1 3 3 3 2 GDP-mannose 4,6 dehydratase NmrA PF05368.13 ABK71361.1 - 0.035 13.7 0.1 0.053 13.1 0.1 1.4 1 1 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.17 ABK71361.1 - 0.043 12.9 0.0 0.085 11.9 0.0 1.4 1 1 0 1 1 1 0 RmlD substrate binding domain FtsK_SpoIIIE PF01580.18 ABK71362.1 - 4.5e-60 203.0 0.0 1.6e-47 162.0 0.0 2.4 2 1 0 2 2 2 2 FtsK/SpoIIIE family AAA_16 PF13191.6 ABK71362.1 - 7.5e-07 29.7 0.0 0.0026 18.2 0.0 2.7 3 0 0 3 3 3 2 AAA ATPase domain AAA_25 PF13481.6 ABK71362.1 - 1.6e-05 24.6 0.0 0.0055 16.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ABK71362.1 - 0.00013 22.3 0.0 0.44 10.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 ABK71362.1 - 0.00071 20.1 0.0 1.4 9.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 ABK71362.1 - 0.0011 18.9 0.0 1.1 9.2 0.0 3.0 3 0 0 3 3 3 1 NACHT domain RNA_helicase PF00910.22 ABK71362.1 - 0.0011 19.3 0.0 0.89 10.0 0.0 2.6 2 0 0 2 2 2 2 RNA helicase KTI12 PF08433.10 ABK71362.1 - 0.0018 17.8 0.0 0.21 11.0 0.0 2.7 3 0 0 3 3 3 1 Chromatin associated protein KTI12 IstB_IS21 PF01695.17 ABK71362.1 - 0.0094 15.7 0.0 1 9.0 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_19 PF13245.6 ABK71362.1 - 0.014 15.7 0.0 7 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 ABK71362.1 - 0.015 15.7 0.0 0.34 11.4 0.0 2.8 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 ABK71362.1 - 0.016 15.3 0.0 0.28 11.3 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 ABK71362.1 - 0.047 13.4 0.0 4 7.2 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 ABK71362.1 - 0.051 13.0 0.0 2.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 ABK71362.1 - 0.12 12.6 0.0 22 5.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 ABK71362.1 - 0.16 11.7 0.0 11 5.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 ABK71362.1 - 0.22 11.4 0.0 30 4.5 0.0 2.5 2 0 0 2 2 2 0 NTPase AMP-binding PF00501.28 ABK71363.1 - 2.7e-72 243.7 0.0 3.4e-72 243.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK71363.1 - 3.4e-16 60.0 0.0 1.6e-15 57.8 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF5111 PF17138.4 ABK71363.1 - 0.062 13.2 0.0 0.26 11.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5111) OHCU_decarbox PF09349.10 ABK71365.1 - 3e-39 135.0 0.0 3.4e-39 134.8 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase YkuD_2 PF13645.6 ABK71365.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain YbaB_DNA_bd PF02575.16 ABK71366.1 - 0.017 15.4 0.0 0.027 14.7 0.0 1.3 1 0 0 1 1 1 0 YbaB/EbfC DNA-binding family Fer4_15 PF13459.6 ABK71367.1 - 5.6e-15 55.8 0.0 7.1e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_13 PF13370.6 ABK71367.1 - 1.4e-08 35.1 0.0 1.9e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_19 PF06902.11 ABK71367.1 - 0.066 13.3 0.0 0.087 12.9 0.0 1.3 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Glycos_transf_3 PF00591.21 ABK71368.1 - 2.2e-89 299.4 2.0 2.8e-89 299.1 2.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 ABK71368.1 - 2e-13 49.9 1.5 6.5e-13 48.3 0.1 2.3 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain BPD_transp_1 PF00528.22 ABK71369.1 - 2.3e-14 53.6 22.5 2.3e-14 53.6 22.5 2.2 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component LapA_dom PF06305.11 ABK71369.1 - 0.8 9.6 9.3 0.78 9.6 1.8 2.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain PPE PF00823.19 ABK71370.1 - 4.6 7.3 11.6 0.19 11.8 3.9 2.5 3 0 0 3 3 3 0 PPE family Ribonuclease PF00545.20 ABK71372.1 - 6.6e-30 103.7 0.0 8e-30 103.4 0.0 1.1 1 0 0 1 1 1 1 ribonuclease Sigma70_r2 PF04542.14 ABK71373.1 - 1.2e-18 66.6 0.6 1.2e-18 66.6 0.6 1.6 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 ABK71373.1 - 1e-16 60.3 0.2 2.2e-16 59.3 0.2 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 ABK71373.1 - 1.7e-08 33.8 3.0 1.7e-08 33.8 0.5 2.3 2 1 1 3 3 3 1 Sigma-70, region 4 HTH_23 PF13384.6 ABK71373.1 - 0.0042 16.8 0.3 0.028 14.2 0.1 2.5 1 1 1 2 2 2 1 Homeodomain-like domain HTH_40 PF14493.6 ABK71373.1 - 0.0044 17.4 0.5 2.7 8.5 0.0 3.0 1 1 2 3 3 3 2 Helix-turn-helix domain HTH_24 PF13412.6 ABK71373.1 - 0.013 15.0 0.1 0.087 12.4 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 ABK71373.1 - 0.027 14.3 0.5 1 9.2 0.0 2.5 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_28 PF13518.6 ABK71373.1 - 0.8 9.9 4.5 0.53 10.5 0.3 2.8 2 1 0 2 2 2 0 Helix-turn-helix domain TetR_N PF00440.23 ABK71374.1 - 8.4e-16 57.5 0.0 1.6e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_33 PF13305.6 ABK71374.1 - 0.017 15.9 1.4 0.017 15.9 1.4 2.9 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK71375.1 - 5.8e-13 48.4 0.3 1.3e-12 47.2 0.3 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 ABK71375.1 - 0.0058 16.9 2.5 0.0077 16.5 0.0 2.3 2 1 0 3 3 3 1 Tetracyclin repressor-like, C-terminal domain HTH_IclR PF09339.10 ABK71376.1 - 5.3e-09 35.7 0.6 5.3e-09 35.7 0.6 2.0 2 0 0 2 2 2 1 IclR helix-turn-helix domain MarR_2 PF12802.7 ABK71376.1 - 5.2e-05 23.1 0.3 0.00055 19.8 0.1 2.3 2 0 0 2 2 2 1 MarR family IclR PF01614.18 ABK71376.1 - 0.00015 21.6 0.0 0.00034 20.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_27 PF13463.6 ABK71376.1 - 0.00044 20.7 0.1 0.0013 19.2 0.1 1.8 1 1 0 1 1 1 1 Winged helix DNA-binding domain DUF742 PF05331.11 ABK71376.1 - 0.022 14.5 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF742) ssDNA_TraI_N PF18272.1 ABK71376.1 - 0.026 14.5 0.6 0.87 9.6 0.6 2.7 3 0 0 3 3 3 0 single-stranded DNA binding TraI N-terminal subdomain HTH_20 PF12840.7 ABK71376.1 - 0.063 13.3 0.2 0.19 11.8 0.2 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain RPA_C PF08784.11 ABK71376.1 - 0.08 13.6 0.0 0.15 12.7 0.0 1.4 1 0 0 1 1 1 0 Replication protein A C terminal OSCP PF00213.18 ABK71377.1 - 1.3e-31 110.1 10.5 4.5e-28 98.5 0.0 3.7 3 1 0 3 3 3 2 ATP synthase delta (OSCP) subunit ATP-synt_B PF00430.18 ABK71377.1 - 1.2e-19 70.6 18.5 1.2e-19 70.6 18.5 2.2 2 0 0 2 2 2 1 ATP synthase B/B' CF(0) YjbH PF06082.11 ABK71377.1 - 0.79 8.5 6.0 1.1 8.0 6.0 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH DciA PF05258.12 ABK71377.1 - 1 9.8 7.1 1.1 9.8 0.7 3.9 4 1 0 4 4 4 0 Dna[CI] antecedent, DciA PRiA4_ORF3 PF07929.11 ABK71378.1 - 2.1e-51 174.1 0.0 2.5e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein Acyl-CoA_dh_1 PF00441.24 ABK71379.1 - 7.4e-30 104.1 0.4 1e-29 103.7 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK71379.1 - 2.9e-26 92.3 0.1 5.6e-26 91.4 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ABK71379.1 - 3.5e-20 72.0 0.0 6.6e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ABK71379.1 - 3.3e-08 33.9 3.6 6.9e-08 32.8 3.6 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyclase PF04199.13 ABK71380.1 - 3.9e-25 88.7 0.1 5.7e-25 88.1 0.1 1.3 1 0 0 1 1 1 1 Putative cyclase Aconitase PF00330.20 ABK71381.1 - 9.6e-163 542.4 0.0 1.1e-162 542.3 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) DUF521 PF04412.13 ABK71381.1 - 0.012 14.4 0.0 0.017 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Latexin PF06907.12 ABK71381.1 - 0.17 11.4 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Latexin Pyr_redox_2 PF07992.14 ABK71382.1 - 1e-47 162.8 0.1 1.5e-47 162.2 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 ABK71382.1 - 5.4e-18 65.0 0.0 1e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 ABK71382.1 - 6.2e-17 61.9 0.3 2.1e-14 53.9 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 ABK71382.1 - 1.4e-15 57.3 8.6 3.3e-09 36.9 6.1 2.7 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain NIR_SIR_ferr PF03460.17 ABK71382.1 - 1.1e-12 47.7 0.0 3.5e-12 46.0 0.0 2.0 2 0 0 2 2 2 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 ABK71382.1 - 1.5e-08 34.4 0.0 3.1e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Rubredoxin NAD+ reductase C-terminal domain FAD_binding_2 PF00890.24 ABK71382.1 - 8.3e-05 21.8 1.5 0.05 12.7 0.1 2.5 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 ABK71382.1 - 0.00032 20.0 0.0 0.39 9.9 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ABK71382.1 - 0.00073 19.2 3.1 0.3 10.6 0.0 3.3 2 2 1 4 4 4 2 FAD dependent oxidoreductase GIDA PF01134.22 ABK71382.1 - 0.00096 18.3 0.1 0.051 12.6 0.2 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 ABK71382.1 - 0.001 19.2 0.4 0.0042 17.3 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 ABK71382.1 - 0.0014 18.0 0.1 0.2 10.9 0.0 2.8 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.6 ABK71382.1 - 0.02 15.3 0.1 3.8 8.0 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 ABK71382.1 - 0.037 13.3 1.7 0.055 12.7 0.1 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 ABK71382.1 - 0.051 12.8 0.3 0.079 12.2 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 ABK71382.1 - 0.1 12.5 0.2 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 ABK71382.1 - 0.11 11.2 0.0 11 4.6 0.1 3.2 2 1 2 4 4 4 0 HI0933-like protein TrkA_N PF02254.18 ABK71382.1 - 0.13 12.5 0.5 4.2 7.6 0.1 2.6 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_9 PF13454.6 ABK71382.1 - 0.59 10.1 4.7 6.1 6.8 0.0 3.7 3 1 1 4 4 4 0 FAD-NAD(P)-binding Myco_arth_vir_N PF09610.10 ABK71383.1 - 0.25 11.5 0.1 0.25 11.5 0.1 3.7 4 0 0 4 4 4 0 Mycoplasma virulence signal region (Myco_arth_vir_N) tRNA-synt_1_2 PF13603.6 ABK71384.1 - 1.2e-57 194.4 0.0 2.5e-57 193.4 0.0 1.5 1 1 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1 PF00133.22 ABK71384.1 - 5.6e-35 120.7 0.0 1.2e-17 63.5 0.0 5.1 3 2 1 4 4 4 4 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 ABK71384.1 - 1.4e-16 60.2 0.0 7e-13 48.1 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 ABK71384.1 - 1.1e-13 51.4 0.0 4.1e-13 49.6 0.0 1.9 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA S4 PF01479.25 ABK71384.1 - 0.1 12.4 1.0 0.3 10.8 0.0 2.2 2 0 0 2 2 2 0 S4 domain tRNA-synt_1e PF01406.19 ABK71384.1 - 0.13 11.6 0.0 16 4.7 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain DUF881 PF05949.12 ABK71385.1 - 2e-39 134.8 0.0 2.6e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF881) DUF898 PF05987.13 ABK71386.1 - 0.00093 18.3 0.6 0.0012 18.0 0.6 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF898) KAR PF15222.6 ABK71386.1 - 0.16 12.3 0.1 0.28 11.5 0.1 1.3 1 0 0 1 1 1 0 Kidney androgen-regulated Phage_holin_3_7 PF05449.11 ABK71386.1 - 1.5 8.9 11.7 0.26 11.3 5.2 2.5 2 1 0 2 2 2 0 Putative 3TM holin, Phage_holin_3 GreA_GreB_N PF03449.15 ABK71387.1 - 1.3e-24 86.2 4.0 1.7e-24 85.7 4.0 1.2 1 0 0 1 1 1 1 Transcription elongation factor, N-terminal GreA_GreB PF01272.19 ABK71387.1 - 8.3e-15 54.5 0.1 1.3e-14 53.9 0.1 1.3 1 0 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term DUF3299 PF11736.8 ABK71387.1 - 0.028 14.4 0.0 0.038 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3299) SbcD_C PF12320.8 ABK71387.1 - 0.13 12.6 0.8 0.23 11.8 0.8 1.4 1 0 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain Fur_reg_FbpA PF13076.6 ABK71388.1 - 0.15 11.8 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Fur-regulated basic protein A Usp PF00582.26 ABK71390.1 - 4.8e-51 173.0 4.3 4.5e-25 88.8 1.6 2.1 2 0 0 2 2 2 2 Universal stress protein family ROK PF00480.20 ABK71391.1 - 7.2e-38 130.7 0.0 9.4e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 ROK family MarR_2 PF12802.7 ABK71391.1 - 1.1e-07 31.6 2.9 4.9e-07 29.5 2.9 2.2 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 ABK71391.1 - 0.0018 17.8 0.6 0.0051 16.3 0.2 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_31 PF13560.6 ABK71391.1 - 0.02 15.2 6.1 0.11 12.8 3.0 3.2 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.6 ABK71391.1 - 0.089 12.9 2.5 0.093 12.9 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_20 PF12840.7 ABK71392.1 - 1.5e-19 69.8 0.4 2.1e-19 69.3 0.4 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 ABK71392.1 - 5.9e-07 29.3 0.8 5.5e-06 26.2 0.8 2.0 1 1 0 1 1 1 1 MarR family HTH_5 PF01022.20 ABK71392.1 - 1.7e-05 24.6 0.2 0.00024 20.9 0.2 2.1 1 1 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 ABK71392.1 - 0.011 15.3 0.1 1.6 8.3 0.1 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Cdc6_C PF09079.11 ABK71392.1 - 0.018 15.0 0.1 0.04 13.9 0.0 1.5 1 1 0 1 1 1 0 CDC6, C terminal winged helix domain HTH_Crp_2 PF13545.6 ABK71392.1 - 0.075 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain MarR PF01047.22 ABK71392.1 - 0.083 12.8 0.0 0.25 11.3 0.0 1.8 1 1 0 1 1 1 0 MarR family HTH_12 PF08461.10 ABK71392.1 - 0.13 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain Herpes_UL46 PF03387.14 ABK71392.1 - 0.17 10.6 0.0 0.18 10.5 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus UL46 protein Fer2_3 PF13085.6 ABK71393.1 - 1e-26 93.1 0.0 1.9e-26 92.2 0.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.6 ABK71393.1 - 2.7e-14 53.4 7.6 1.3e-13 51.2 6.0 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 ABK71393.1 - 5.4e-06 26.3 0.2 5.4e-06 26.3 0.2 2.1 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 ABK71393.1 - 0.00016 22.1 6.1 0.00016 22.1 6.1 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.6 ABK71393.1 - 0.00017 21.8 5.7 0.11 12.7 0.2 2.5 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 ABK71393.1 - 0.0039 17.3 9.4 0.12 12.5 0.3 3.2 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 ABK71393.1 - 0.033 14.8 12.4 0.035 14.7 7.7 2.8 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 ABK71393.1 - 0.16 12.9 8.1 0.79 10.7 0.3 2.9 3 0 0 3 3 3 0 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 ABK71393.1 - 0.21 11.7 16.6 1.1 9.5 11.4 3.1 2 1 2 4 4 4 0 4Fe-4S dicluster domain Ribonuc_L-PSP PF01042.21 ABK71395.1 - 8.8e-14 51.6 0.0 1.2e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Endoribonuclease L-PSP YjgF_endoribonc PF14588.6 ABK71395.1 - 5e-11 42.9 0.0 5.9e-11 42.7 0.0 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease AMP-binding PF00501.28 ABK71396.1 - 1.7e-61 208.1 0.0 2.1e-61 207.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK71396.1 - 2.6e-10 41.1 0.0 5.3e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LRV PF01816.17 ABK71396.1 - 0.0094 16.3 0.2 0.094 13.2 0.2 2.9 1 0 0 1 1 1 1 Leucine rich repeat variant MraZ PF02381.18 ABK71397.1 - 1.9e-45 152.7 0.1 7.8e-22 77.1 0.1 2.0 2 0 0 2 2 2 2 MraZ protein, putative antitoxin-like Glycos_transf_2 PF00535.26 ABK71398.1 - 1.2e-11 44.7 0.0 1.5e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ABK71398.1 - 0.00017 21.1 1.9 0.012 15.1 0.1 2.3 1 1 1 2 2 2 2 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 ABK71398.1 - 0.0096 15.9 1.0 0.041 13.8 0.1 2.0 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Helicase_C_3 PF13625.6 ABK71398.1 - 0.1 12.8 0.1 0.34 11.1 0.0 1.8 2 0 0 2 2 2 0 Helicase conserved C-terminal domain Cpn60_TCP1 PF00118.24 ABK71399.1 - 7.3e-90 301.9 13.1 2.5e-89 300.1 13.1 1.7 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Abhydrolase_1 PF00561.20 ABK71400.1 - 3.5e-27 95.7 0.0 4.1e-27 95.5 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ABK71400.1 - 0.0011 18.3 0.1 0.0021 17.4 0.1 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 ABK71400.1 - 0.13 11.8 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Putative esterase AraC_N PF06719.13 ABK71404.1 - 2.2e-40 137.7 0.0 3.2e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 AraC-type transcriptional regulator N-terminus HTH_18 PF12833.7 ABK71404.1 - 2.4e-20 72.6 1.4 7.4e-20 71.0 1.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 ABK71404.1 - 4.2e-15 55.4 0.0 2.6e-09 36.9 0.0 2.5 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding PF02311.19 ABK71404.1 - 0.0057 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain TetR_N PF00440.23 ABK71404.1 - 0.057 13.2 2.1 0.13 12.1 0.0 2.6 3 0 0 3 3 3 0 Bacterial regulatory proteins, tetR family YqzH PF14164.6 ABK71404.1 - 0.27 11.3 0.4 1.3 9.1 0.0 2.1 2 0 0 2 2 2 0 YqzH-like protein Gly_kinase PF02595.15 ABK71405.1 - 9.3e-136 452.6 8.5 1e-135 452.4 8.5 1.0 1 0 0 1 1 1 1 Glycerate kinase family APS_kinase PF01583.20 ABK71407.1 - 5.1e-66 221.4 0.0 9.4e-66 220.6 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase GTP_EFTU PF00009.27 ABK71407.1 - 2.5e-40 138.1 0.1 3.7e-40 137.6 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 ABK71407.1 - 4.6e-08 33.3 0.1 9.8e-07 29.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 ABK71407.1 - 6.2e-07 29.5 0.5 2.8e-05 24.2 0.1 3.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 ABK71407.1 - 2.5e-06 27.8 0.0 1.6e-05 25.2 0.0 2.4 3 0 0 3 3 3 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 ABK71407.1 - 0.0013 18.6 0.1 2 8.3 0.0 3.5 3 1 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 ABK71407.1 - 0.0018 18.7 0.0 0.0048 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 ABK71407.1 - 0.047 13.5 0.6 1.3 8.8 0.1 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain PRK PF00485.18 ABK71407.1 - 0.071 12.8 0.0 0.17 11.6 0.0 1.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.27 ABK71407.1 - 0.12 12.9 0.0 0.73 10.3 0.0 2.2 2 0 0 2 2 2 0 ABC transporter SRPRB PF09439.10 ABK71407.1 - 0.16 11.4 0.1 5.8 6.3 0.0 2.9 2 1 1 3 3 3 0 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 ABK71407.1 - 0.17 12.5 0.0 0.61 10.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain Hydrolase PF00702.26 ABK71408.1 - 5.5e-12 46.4 0.0 1.4e-11 45.1 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ABK71408.1 - 7.8e-10 39.1 0.0 1.5e-09 38.2 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ABK71408.1 - 8.4e-06 25.8 0.0 1.9e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 ABK71408.1 - 0.00032 20.8 0.0 0.00086 19.4 0.0 1.8 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 ABK71408.1 - 0.0053 17.2 0.0 0.0068 16.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase MFS_1 PF07690.16 ABK71409.1 - 5e-30 104.6 103.4 2.3e-27 95.9 63.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ABK71409.1 - 2e-08 33.9 59.5 2.4e-08 33.7 59.5 1.0 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB DUF5316 PF17247.2 ABK71409.1 - 3.2 7.8 6.0 2 8.5 0.2 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5316) Trp_oprn_chp PF09534.10 ABK71410.1 - 0.01 15.7 0.7 0.011 15.6 0.7 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF1345 PF07077.11 ABK71410.1 - 0.013 15.2 0.1 0.016 14.9 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) DUF1129 PF06570.11 ABK71410.1 - 0.047 13.2 0.0 0.053 13.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) PEMT PF04191.13 ABK71410.1 - 0.11 12.9 1.5 0.17 12.3 0.2 1.8 1 1 1 2 2 2 0 Phospholipid methyltransferase PRTase_1 PF11202.8 ABK71410.1 - 0.18 11.0 0.1 0.19 10.9 0.1 1.1 1 0 0 1 1 1 0 Phosphoribosyl transferase (PRTase) LapA_dom PF06305.11 ABK71410.1 - 2.8 7.8 4.9 1.3 8.9 2.2 1.7 1 1 1 2 2 2 0 Lipopolysaccharide assembly protein A domain PRiA4_ORF3 PF07929.11 ABK71411.1 - 2.1e-51 174.1 0.0 2.5e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein DUF2059 PF09832.9 ABK71412.1 - 1.9 8.6 7.5 5.7 7.1 0.0 2.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2059) MFS_1 PF07690.16 ABK71413.1 - 7.1e-33 114.0 57.9 2.2e-25 89.3 29.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ABK71413.1 - 5.4e-06 26.0 46.7 8.7e-06 25.3 46.7 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 ABK71413.1 - 0.15 10.9 7.8 1.1 8.1 2.6 2.6 1 1 1 2 2 2 0 MFS_1 like family Pup_ligase PF03136.15 ABK71414.1 - 2.1e-181 603.8 0.0 2.4e-181 603.6 0.0 1.0 1 0 0 1 1 1 1 Pup-ligase protein Ribonuc_red_sm PF00268.21 ABK71415.1 - 9.7e-94 313.9 0.4 1.1e-93 313.7 0.4 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF1289 PF06945.13 ABK71415.1 - 0.15 11.9 1.5 13 5.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1289) DUF3147 PF11345.8 ABK71416.1 - 0.062 13.7 0.3 0.13 12.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3147) Urease_beta PF00699.20 ABK71417.1 - 1.3e-40 137.4 0.0 1.4e-40 137.2 0.0 1.0 1 0 0 1 1 1 1 Urease beta subunit 2-Hacid_dh_C PF02826.19 ABK71418.1 - 1e-59 200.9 0.0 1.4e-59 200.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ABK71418.1 - 1.8e-26 92.4 0.1 2e-26 92.2 0.1 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.12 ABK71418.1 - 0.00083 19.0 0.1 0.0019 17.8 0.0 1.6 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 ABK71418.1 - 0.0035 17.4 0.0 0.15 12.1 0.0 2.2 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Sacchrp_dh_NADP PF03435.18 ABK71418.1 - 0.02 15.2 0.1 0.82 9.9 0.0 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 ABK71418.1 - 0.034 14.4 0.9 2.6 8.3 0.0 2.6 2 1 0 2 2 2 0 TrkA-N domain Gp_dh_N PF00044.24 ABK71418.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DUF3349 PF11829.8 ABK71419.1 - 1.8e-33 115.2 0.1 2.1e-33 115.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3349) zinc_ribbon_4 PF13717.6 ABK71420.1 - 0.02 14.8 2.2 0.065 13.2 2.2 1.8 1 1 1 2 2 2 0 zinc-ribbon domain HypA PF01155.19 ABK71420.1 - 0.13 12.3 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-trcl PF13451.6 ABK71420.1 - 2.7 8.0 4.3 34 4.4 4.3 2.0 1 1 0 1 1 1 0 Probable zinc-ribbon domain ECH_1 PF00378.20 ABK71421.1 - 1.4e-20 73.7 3.5 1.5e-20 73.6 3.5 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK71421.1 - 2e-10 40.7 1.2 2.9e-10 40.2 1.2 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF1344 PF07076.11 ABK71421.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) Rrf2 PF02082.20 ABK71422.1 - 1.3e-25 89.5 0.1 5.2e-25 87.6 0.0 1.9 2 0 0 2 2 2 1 Transcriptional regulator TFIIE_alpha PF02002.17 ABK71422.1 - 0.0089 15.9 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit FCSD-flav_bind PF09242.11 ABK71422.1 - 0.057 13.8 0.0 3.3 8.1 0.0 2.5 2 0 0 2 2 2 0 Flavocytochrome c sulphide dehydrogenase, flavin-binding Zn_peptidase PF04228.13 ABK71423.1 - 3.9e-07 29.8 0.2 1.3e-05 24.8 0.0 3.0 3 1 0 3 3 3 1 Putative neutral zinc metallopeptidase STAS_2 PF13466.6 ABK71423.1 - 0.1 13.0 1.9 0.29 11.5 0.4 2.4 2 1 1 3 3 3 0 STAS domain Mycobact_memb PF05423.13 ABK71424.1 - 2.9e-09 37.0 0.6 9.1e-08 32.1 0.0 2.1 2 0 0 2 2 2 2 Mycobacterium membrane protein DUF4245 PF14030.6 ABK71424.1 - 0.063 13.3 1.3 0.12 12.4 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4245) Arginase PF00491.21 ABK71425.1 - 5.8e-94 314.7 1.6 7.2e-94 314.4 1.6 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 ABK71425.1 - 0.089 13.0 0.8 0.13 12.5 0.8 1.2 1 0 0 1 1 1 0 UPF0489 domain SnoaL_2 PF12680.7 ABK71426.1 - 1.5e-09 38.4 0.7 2e-09 38.0 0.7 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 ABK71426.1 - 8.4e-06 25.6 0.9 3.6e-05 23.6 0.9 1.8 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase MDMPI_N PF11716.8 ABK71427.1 - 6.7e-12 46.3 3.9 6.7e-12 46.3 3.9 1.5 2 0 0 2 2 2 1 Mycothiol maleylpyruvate isomerase N-terminal domain BPD_transp_1 PF00528.22 ABK71429.1 - 3e-21 76.0 16.6 3e-21 76.0 16.6 1.7 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component LMBR1 PF04791.16 ABK71429.1 - 0.016 14.2 0.6 0.016 14.2 0.6 1.9 2 0 0 2 2 2 0 LMBR1-like membrane protein Claudin_2 PF13903.6 ABK71429.1 - 1.5 8.6 12.4 0.96 9.2 4.2 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Abhydrolase_6 PF12697.7 ABK71430.1 - 3.1e-22 80.3 4.9 3.8e-22 80.0 4.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ABK71430.1 - 2.9e-13 50.0 0.0 7.8e-12 45.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ABK71430.1 - 4.6e-10 39.2 0.1 1.5e-09 37.5 0.1 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 ABK71430.1 - 0.013 15.2 0.0 0.024 14.3 0.0 1.5 1 1 0 1 1 1 0 Putative esterase Ndr PF03096.14 ABK71430.1 - 0.013 14.2 0.0 1.1 7.9 0.0 2.1 2 0 0 2 2 2 0 Ndr family UPF0227 PF05728.12 ABK71430.1 - 0.13 12.2 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Ser_hydrolase PF06821.13 ABK71430.1 - 0.16 11.8 0.4 1.6 8.6 0.1 2.1 2 0 0 2 2 2 0 Serine hydrolase PemK_toxin PF02452.17 ABK71432.1 - 8.1e-10 39.1 0.0 1.3e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 PemK-like, MazF-like toxin of type II toxin-antitoxin system WES_acyltransf PF03007.16 ABK71433.1 - 1.3e-35 123.5 9.0 7.6e-34 117.7 9.0 2.1 1 1 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 ABK71433.1 - 7.9e-20 71.3 0.0 1.3e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) AATase PF07247.12 ABK71433.1 - 0.22 10.0 0.0 0.31 9.5 0.0 1.1 1 0 0 1 1 1 0 Alcohol acetyltransferase MHB PF16525.5 ABK71434.1 - 2.3e-28 98.2 0.4 3e-28 97.9 0.4 1.1 1 0 0 1 1 1 1 Haemophore, haem-binding ECH_1 PF00378.20 ABK71435.1 - 5.9e-62 209.2 0.0 6.8e-62 209.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK71435.1 - 2.4e-35 122.6 0.0 2.7e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase UPF0444 PF15475.6 ABK71435.1 - 0.02 15.2 0.0 0.041 14.1 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein C12orf23, UPF0444 SNARE_assoc PF09335.11 ABK71436.1 - 1.7e-20 73.7 5.5 1.7e-20 73.7 5.5 1.9 3 0 0 3 3 3 1 SNARE associated Golgi protein Pam17 PF08566.10 ABK71436.1 - 0.001 18.9 0.1 0.001 18.9 0.1 1.8 2 1 0 2 2 2 1 Mitochondrial import protein Pam17 PHO4 PF01384.20 ABK71436.1 - 4.8 6.1 11.4 0.67 8.9 2.8 2.0 1 1 1 2 2 2 0 Phosphate transporter family ETF PF01012.21 ABK71437.1 - 2.3e-43 148.2 4.7 2.8e-43 147.9 4.7 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain adh_short_C2 PF13561.6 ABK71438.1 - 3.9e-61 206.6 1.1 5.2e-61 206.2 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK71438.1 - 3e-52 176.9 0.1 3.6e-52 176.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK71438.1 - 7.3e-18 65.1 0.1 1.2e-17 64.4 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ABK71438.1 - 1.9e-07 31.2 0.5 2.3e-07 30.9 0.5 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3HCDH_N PF02737.18 ABK71438.1 - 0.00029 20.8 0.1 0.00045 20.2 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 ABK71438.1 - 0.00033 20.2 0.3 0.00058 19.4 0.3 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 ABK71438.1 - 0.0091 16.3 0.4 0.022 15.0 0.2 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Adenine_deam_C PF13382.6 ABK71438.1 - 0.2 11.0 1.9 0.51 9.7 0.4 2.2 2 0 0 2 2 2 0 Adenine deaminase C-terminal domain MFS_1 PF07690.16 ABK71439.1 - 6.2e-35 120.8 81.7 4.4e-26 91.6 43.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATPase_gene1 PF09527.10 ABK71439.1 - 0.00055 20.0 4.4 0.00055 20.0 4.4 4.2 2 1 1 3 3 3 1 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter MFS_4 PF06779.14 ABK71439.1 - 0.075 12.3 50.6 0.21 10.8 47.7 2.0 1 1 1 2 2 2 0 Uncharacterised MFS-type transporter YbfB Transpeptidase PF00905.22 ABK71440.1 - 4.9e-90 301.8 0.0 7.1e-90 301.3 0.0 1.2 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain PBP_dimer PF03717.15 ABK71440.1 - 3.6e-12 47.0 0.5 3.7e-10 40.4 0.5 2.5 1 1 0 1 1 1 1 Penicillin-binding Protein dimerisation domain Beta-lactamase2 PF13354.6 ABK71440.1 - 3e-05 23.7 0.0 0.00044 19.9 0.0 2.6 2 1 0 2 2 2 1 Beta-lactamase enzyme family Fer2_2 PF01799.20 ABK71441.1 - 3.5e-29 100.6 2.0 9.2e-29 99.3 0.2 2.0 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fer2 PF00111.27 ABK71441.1 - 3.8e-08 33.2 0.9 3.8e-08 33.2 0.9 2.3 1 1 1 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 ABK71441.1 - 0.00015 21.8 0.5 0.00015 21.8 0.5 1.5 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 ABK71441.1 - 0.0081 16.2 1.6 0.034 14.2 1.6 2.0 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain LacAB_rpiB PF02502.18 ABK71442.1 - 1.3e-44 151.6 0.2 1.4e-44 151.4 0.2 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase DUF4514 PF14986.6 ABK71442.1 - 0.03 14.3 0.8 0.085 12.8 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4514) DUF4536 PF15055.6 ABK71443.1 - 0.077 13.2 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4536) MSA-2c PF12238.8 ABK71443.1 - 4 7.4 6.7 6.1 6.8 6.7 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c Glyco_trans_4_4 PF13579.6 ABK71444.1 - 7.2e-24 85.0 9.0 7.2e-24 85.0 9.0 2.2 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.20 ABK71444.1 - 3.1e-13 49.6 0.0 4.4e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ABK71444.1 - 5.2e-11 43.1 0.1 7.9e-11 42.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ABK71444.1 - 8.3e-10 38.9 1.7 1.6e-09 38.0 1.7 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.11 ABK71444.1 - 0.096 12.4 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Starch synthase catalytic domain HypD PF01924.16 ABK71445.1 - 5.1e-151 502.7 0.0 5.8e-151 502.5 0.0 1.0 1 0 0 1 1 1 1 Hydrogenase formation hypA family STAS_2 PF13466.6 ABK71446.1 - 0.00042 20.6 0.0 0.0011 19.3 0.0 1.7 1 1 0 1 1 1 1 STAS domain STAS PF01740.21 ABK71446.1 - 0.0029 17.2 0.0 0.0035 16.9 0.0 1.1 1 0 0 1 1 1 1 STAS domain Mannitol_dh_C PF08125.13 ABK71447.1 - 9.2e-72 241.5 0.0 1.2e-71 241.1 0.0 1.1 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 ABK71447.1 - 1.1e-31 110.1 0.0 2.6e-31 108.8 0.0 1.7 1 1 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain ABC_tran PF00005.27 ABK71448.1 - 6.9e-34 117.3 0.0 1.1e-33 116.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ABK71448.1 - 2.8e-09 36.7 0.2 4.9e-05 22.9 0.0 2.4 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_membrane PF00664.23 ABK71448.1 - 7.4e-05 22.5 0.0 9.3e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_29 PF13555.6 ABK71448.1 - 0.00011 21.9 0.1 0.00028 20.6 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 ABK71448.1 - 0.00014 21.8 0.0 0.0013 18.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 ABK71448.1 - 0.00033 20.4 2.5 0.0035 17.1 2.5 2.3 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ABK71448.1 - 0.00042 20.3 0.0 0.00085 19.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 ABK71448.1 - 0.0027 18.2 0.0 0.0042 17.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ABK71448.1 - 0.0034 17.8 3.6 0.026 14.9 3.6 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ABK71448.1 - 0.014 15.6 0.1 0.26 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 ABK71448.1 - 0.015 14.1 0.5 0.64 8.8 0.1 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_33 PF13671.6 ABK71448.1 - 0.032 14.4 0.8 1.5 8.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 ABK71448.1 - 0.094 12.0 0.1 1.6 8.0 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_15 PF13175.6 ABK71448.1 - 0.1 12.3 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.6 ABK71448.1 - 2 8.7 4.0 11 6.3 1.5 3.0 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit HAD PF12710.7 ABK71449.1 - 3.6e-31 109.0 0.3 4.8e-31 108.6 0.3 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ABK71449.1 - 8.4e-06 26.2 0.6 1.3e-05 25.6 0.1 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ABK71449.1 - 0.00016 21.5 0.0 0.00034 20.5 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ECH_1 PF00378.20 ABK71450.1 - 3.8e-44 150.9 0.0 4.5e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK71450.1 - 2.6e-29 102.8 0.2 3.1e-29 102.5 0.2 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase SDH_sah PF01972.16 ABK71450.1 - 0.0045 16.0 0.0 0.0083 15.2 0.0 1.4 1 0 0 1 1 1 1 Serine dehydrogenase proteinase DLH PF01738.18 ABK71450.1 - 0.014 14.9 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 ABK71451.1 - 4.3e-14 52.8 0.1 3.4e-11 43.3 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ABK71451.1 - 3.7e-08 32.9 0.2 8e-08 31.8 0.2 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ABK71451.1 - 6.2e-08 33.5 8.0 9e-08 33.0 8.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ABK71451.1 - 0.00075 19.0 0.1 0.47 9.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF1057 PF06342.12 ABK71451.1 - 0.0019 17.3 0.0 0.0026 16.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_2 PF02230.16 ABK71451.1 - 0.11 12.3 0.1 0.93 9.3 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.20 ABK71451.1 - 0.22 11.2 0.2 0.33 10.6 0.2 1.3 1 0 0 1 1 1 0 Putative esterase Bac_luciferase PF00296.20 ABK71452.1 - 4.7e-15 55.8 0.0 5.5e-15 55.6 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase ADH_N PF08240.12 ABK71453.1 - 4.2e-28 97.4 2.0 4.6e-28 97.3 0.9 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ABK71453.1 - 2.7e-25 88.8 0.9 4.2e-25 88.2 0.9 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ABK71453.1 - 3.5e-09 37.8 0.2 7.8e-09 36.7 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 ABK71453.1 - 0.051 12.9 0.1 0.086 12.2 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_N_2 PF16884.5 ABK71453.1 - 0.11 12.4 0.0 0.35 10.8 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase Response_reg PF00072.24 ABK71454.1 - 0.001 19.2 0.0 0.0012 19.0 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain DUF1957 PF09210.11 ABK71455.1 - 2.5e-20 72.7 0.1 4.6e-20 71.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1957) Glyco_hydro_57 PF03065.15 ABK71455.1 - 3.1e-16 59.5 0.0 9.6e-16 57.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 HTH_1 PF00126.27 ABK71456.1 - 1e-21 76.6 6.5 2.5e-21 75.4 6.5 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 ABK71456.1 - 1.1e-20 73.9 3.2 2.4e-20 72.8 3.2 1.5 1 0 0 1 1 1 1 LysR substrate binding domain HTH_30 PF13556.6 ABK71456.1 - 0.0027 17.5 0.4 0.0063 16.3 0.4 1.7 1 1 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.6 ABK71456.1 - 0.0086 16.2 0.2 0.024 14.8 0.2 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain Exonuc_VII_L PF02601.15 ABK71456.1 - 0.16 11.5 0.8 14 5.1 0.0 2.7 2 1 1 3 3 3 0 Exonuclease VII, large subunit DUF4333 PF14230.6 ABK71457.1 - 2.7e-21 75.6 0.3 3.4e-21 75.2 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4333) DUF3357 PF11837.8 ABK71457.1 - 0.023 15.2 0.1 0.036 14.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Sua5_yciO_yrdC PF01300.18 ABK71458.1 - 1.5e-47 161.4 0.0 2.3e-47 160.8 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination zf-HYPF PF07503.12 ABK71458.1 - 1.3e-31 108.1 21.1 2.1e-16 59.4 7.9 2.7 2 0 0 2 2 2 2 HypF finger HypF_C PF17788.1 ABK71458.1 - 3.8e-30 104.6 0.8 7.8e-30 103.6 0.8 1.5 1 0 0 1 1 1 1 HypF Kae1-like domain Acylphosphatase PF00708.18 ABK71458.1 - 4.3e-21 75.1 0.0 1.2e-20 73.7 0.0 1.8 2 0 0 2 2 2 1 Acylphosphatase HD_4 PF13328.6 ABK71458.1 - 0.0033 17.2 3.1 0.011 15.4 0.4 2.4 2 0 0 2 2 2 1 HD domain DUF4072 PF13284.6 ABK71458.1 - 0.089 13.2 5.4 0.097 13.1 0.3 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4072) NMD3 PF04981.13 ABK71458.1 - 0.51 9.7 6.4 1.8 8.0 0.6 2.1 1 1 1 2 2 2 0 NMD3 family p450 PF00067.22 ABK71459.1 - 9.2e-21 74.1 0.0 3.6e-19 68.9 0.0 2.2 1 1 0 1 1 1 1 Cytochrome P450 Glycos_transf_4 PF00953.21 ABK71461.1 - 8.3e-34 116.9 17.5 8.3e-34 116.9 17.5 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 4 ABC-3 PF00950.17 ABK71462.1 - 4e-50 170.7 36.3 4.9e-50 170.4 36.3 1.0 1 0 0 1 1 1 1 ABC 3 transport family FecCD PF01032.18 ABK71462.1 - 2.3e-06 26.8 38.9 4e-06 26.1 38.8 1.4 1 1 0 1 1 1 1 FecCD transport family TPP_enzyme_N PF02776.18 ABK71463.1 - 8.6e-44 149.2 1.2 1.2e-42 145.5 1.1 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 ABK71463.1 - 1.1e-33 116.2 0.1 3.4e-33 114.6 0.1 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 ABK71463.1 - 8.1e-31 106.6 0.3 2.8e-30 104.9 0.1 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Rieske PF00355.26 ABK71463.1 - 8.8e-15 54.4 0.0 1.8e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 ABK71463.1 - 4.2e-08 33.1 0.0 7.9e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Glyco_transf_4 PF13439.6 ABK71463.1 - 0.045 13.7 0.0 0.094 12.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 SnoaL PF07366.12 ABK71464.1 - 2.4e-07 30.6 0.0 2.8e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 ABK71464.1 - 1.5e-06 28.7 0.3 1.9e-06 28.4 0.3 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 ABK71464.1 - 0.0037 17.6 0.0 0.0068 16.8 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) ABC_tran PF00005.27 ABK71465.1 - 4.4e-31 108.2 0.0 7.1e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK71465.1 - 1e-08 35.3 0.0 0.004 17.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 ABK71465.1 - 8e-05 22.0 0.0 0.00016 21.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 ABK71465.1 - 0.00013 22.2 0.0 0.00025 21.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ABK71465.1 - 0.00043 20.0 0.1 0.00089 19.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ABK71465.1 - 0.0019 18.2 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase ABC_ATPase PF09818.9 ABK71465.1 - 0.0033 16.3 0.5 0.13 11.0 0.0 2.4 2 1 0 2 2 2 1 Predicted ATPase of the ABC class AAA_16 PF13191.6 ABK71465.1 - 0.0078 16.6 3.7 0.031 14.7 3.7 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 ABK71465.1 - 0.01 16.0 0.6 0.068 13.3 0.6 2.0 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 ABK71465.1 - 0.047 13.6 0.2 0.12 12.3 0.2 1.7 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 ABK71465.1 - 0.049 13.7 0.1 0.48 10.5 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.29 ABK71465.1 - 0.05 14.0 0.0 0.18 12.2 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 ABK71465.1 - 0.072 13.6 0.0 0.1 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 ABK71465.1 - 0.076 13.1 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_25 PF13481.6 ABK71465.1 - 0.091 12.3 1.0 0.51 9.9 0.0 2.3 2 1 0 2 2 2 0 AAA domain G-alpha PF00503.20 ABK71465.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit AAA_28 PF13521.6 ABK71465.1 - 0.14 12.4 0.6 0.57 10.4 0.1 2.1 2 1 0 2 2 2 0 AAA domain SMC_N PF02463.19 ABK71465.1 - 0.2 11.1 0.0 14 5.1 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AA_permease PF00324.21 ABK71466.1 - 1.5e-14 53.5 40.5 2.7e-14 52.7 40.5 1.4 1 1 0 1 1 1 1 Amino acid permease DUF3098 PF11297.8 ABK71466.1 - 0.021 14.4 0.4 0.59 9.8 0.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3098) CPP1-like PF11833.8 ABK71466.1 - 6.2 6.4 7.5 11 5.6 5.7 2.5 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like YidD PF01809.18 ABK71467.1 - 2.6e-27 94.5 0.2 3.4e-27 94.1 0.2 1.2 1 0 0 1 1 1 1 Putative membrane protein insertion efficiency factor DUF3416 PF11896.8 ABK71468.1 - 1.2e-57 195.1 0.0 1.8e-57 194.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3416) Alpha-amylase PF00128.24 ABK71468.1 - 2.6e-06 27.2 0.0 0.00021 21.0 0.0 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain GHL6 PF14871.6 ABK71468.1 - 0.00018 21.6 0.0 0.00034 20.8 0.0 1.4 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase 6 Glyco_tranf_2_3 PF13641.6 ABK71469.1 - 1e-29 104.1 0.6 1.5e-29 103.6 0.6 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 ABK71469.1 - 4.6e-29 101.4 0.1 7.4e-29 100.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Chitin_synth_2 PF03142.15 ABK71469.1 - 9.4e-23 80.6 10.6 1.5e-19 70.1 1.2 2.3 1 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 ABK71469.1 - 9.5e-14 51.8 8.8 9.5e-14 51.8 8.8 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 ABK71469.1 - 4.6e-13 49.0 0.7 1.7e-12 47.2 0.7 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 ABK71469.1 - 0.0004 20.0 0.1 0.00058 19.4 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 ABK71469.1 - 0.0042 17.6 1.0 0.006 17.1 0.1 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF3792 PF12670.7 ABK71469.1 - 0.13 12.5 7.5 0.41 10.8 1.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) NrsF PF06532.11 ABK71469.1 - 0.9 9.2 12.3 0.091 12.5 2.4 2.4 2 0 0 2 2 2 0 Negative regulator of sigma F DUF3995 PF13160.6 ABK71469.1 - 3.7 7.9 10.7 2.3 8.6 2.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) Glyoxalase_6 PF18029.1 ABK71470.1 - 7.4e-18 65.3 4.6 2.5e-09 37.9 0.3 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase PF00903.25 ABK71470.1 - 1.6e-15 57.5 0.6 1.5e-10 41.3 0.1 2.5 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ABK71470.1 - 0.017 15.4 1.7 6.1 7.2 0.2 3.3 2 2 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily S4 PF01479.25 ABK71471.1 - 1.8e-11 43.6 0.0 3.1e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 S4 domain Methyltransf_3 PF01596.17 ABK71473.1 - 6.1e-38 130.1 0.0 7.9e-38 129.8 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 ABK71473.1 - 5.8e-17 62.6 0.1 9.2e-17 62.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ABK71473.1 - 2.4e-09 37.2 0.0 3.7e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 ABK71473.1 - 1e-08 35.1 0.0 1.6e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABK71473.1 - 5.7e-07 30.2 0.1 2.4e-06 28.2 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 ABK71473.1 - 0.00018 21.2 0.0 0.00026 20.7 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Ubie_methyltran PF01209.18 ABK71473.1 - 0.0024 17.2 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family GCD14 PF08704.10 ABK71473.1 - 0.0024 17.6 0.0 0.0032 17.2 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_18 PF12847.7 ABK71473.1 - 0.01 15.8 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 ABK71473.1 - 0.025 14.1 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase HTH_1 PF00126.27 ABK71474.1 - 2.1e-21 75.6 1.0 2.1e-21 75.6 1.0 1.9 3 0 0 3 3 3 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 ABK71474.1 - 5.5e-19 68.4 6.8 7.8e-19 67.9 6.8 1.2 1 0 0 1 1 1 1 LysR substrate binding domain MarR_2 PF12802.7 ABK71474.1 - 0.00082 19.2 0.7 0.76 9.7 0.1 2.7 2 0 0 2 2 2 2 MarR family Aminotran_1_2 PF00155.21 ABK71474.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II HATPase_c PF02518.26 ABK71475.1 - 2e-17 63.7 0.0 3.4e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ABK71475.1 - 2.1e-15 56.5 0.1 4.6e-15 55.4 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 ABK71475.1 - 0.0016 18.4 0.1 0.0088 16.0 0.0 2.1 1 1 1 2 2 2 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 ABK71475.1 - 0.0033 17.2 0.0 0.0059 16.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Acyltransferase PF01553.21 ABK71476.1 - 1.5e-08 34.3 0.0 2.5e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 ABK71476.1 - 0.00057 19.9 0.0 0.001 19.1 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase C-terminus Trep_Strep PF09605.10 ABK71476.1 - 0.0054 16.7 0.1 0.0084 16.1 0.1 1.2 1 0 0 1 1 1 1 Hypothetical bacterial integral membrane protein (Trep_Strep) TPP_enzyme_N PF02776.18 ABK71477.1 - 1.1e-53 181.3 3.0 2.3e-50 170.5 1.8 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 ABK71477.1 - 2.6e-36 124.4 0.0 6.5e-36 123.1 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 ABK71477.1 - 1.7e-32 112.3 0.1 6.6e-30 103.9 0.0 3.1 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain LysR_substrate PF03466.20 ABK71478.1 - 1.9e-40 138.5 10.0 1.9e-40 138.5 10.0 1.9 1 1 1 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 ABK71478.1 - 8.5e-25 86.5 1.9 8.5e-25 86.5 1.9 2.4 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family CN_hydrolase PF00795.22 ABK71479.1 - 1.8e-40 138.9 0.1 2.3e-40 138.6 0.1 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase ABC_tran PF00005.27 ABK71480.1 - 6.7e-34 117.3 0.0 9.2e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK71480.1 - 7.1e-13 49.0 0.0 1.1e-05 25.4 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK71480.1 - 2.5e-07 30.4 0.1 0.0011 18.5 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ABK71480.1 - 4.2e-06 26.4 0.2 8e-06 25.5 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 ABK71480.1 - 9.1e-05 22.9 0.3 0.0002 21.8 0.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_13 PF13166.6 ABK71480.1 - 0.00027 19.7 0.0 0.013 14.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ABK71480.1 - 0.00029 21.1 0.1 0.0024 18.1 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_23 PF13476.6 ABK71480.1 - 0.0014 19.2 0.1 0.0026 18.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 ABK71480.1 - 0.0014 17.5 0.0 0.23 10.2 0.1 2.2 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_28 PF13521.6 ABK71480.1 - 0.0052 17.0 0.0 0.024 14.9 0.0 2.2 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 ABK71480.1 - 0.01 15.8 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 ABK71480.1 - 0.014 15.9 0.0 0.025 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ABK71480.1 - 0.017 14.9 0.7 0.052 13.3 0.1 1.9 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 ABK71480.1 - 0.031 13.9 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 ABK71480.1 - 0.035 14.3 0.1 0.069 13.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 ABK71480.1 - 0.041 14.3 0.0 1.2 9.5 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 ABK71480.1 - 0.082 12.6 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ABK71480.1 - 0.083 12.8 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_15 PF13175.6 ABK71480.1 - 0.099 12.3 0.0 0.86 9.2 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain KdpD PF02702.17 ABK71480.1 - 0.11 11.9 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain TniB PF05621.11 ABK71480.1 - 0.11 11.9 0.0 17 4.8 0.0 2.9 2 1 1 3 3 3 0 Bacterial TniB protein AAA_14 PF13173.6 ABK71480.1 - 0.16 12.0 0.0 0.72 9.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AHSA1 PF08327.11 ABK71481.1 - 1.7e-20 73.5 0.0 2e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 ABK71481.1 - 1.5e-08 35.1 0.2 1.7e-08 34.8 0.2 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Glyco_trans_1_2 PF13524.6 ABK71482.1 - 2.2e-11 44.0 0.3 4.3e-11 43.1 0.3 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 ThiG PF05690.14 ABK71483.1 - 6.1e-107 356.5 6.1 6.9e-107 356.3 6.1 1.0 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 ABK71483.1 - 0.0027 17.2 0.0 0.0077 15.7 0.0 1.7 2 0 0 2 2 2 1 Histidine biosynthesis protein FMN_dh PF01070.18 ABK71483.1 - 0.004 16.2 3.8 0.026 13.6 2.2 2.1 1 1 0 2 2 2 1 FMN-dependent dehydrogenase NanE PF04131.14 ABK71483.1 - 0.0096 15.1 0.8 0.16 11.1 0.2 2.2 1 1 1 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase IMPDH PF00478.25 ABK71483.1 - 0.046 12.7 2.3 0.072 12.1 2.3 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Glyco_transf_20 PF00982.21 ABK71484.1 - 4.7e-158 526.8 0.0 5.3e-158 526.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.20 ABK71484.1 - 0.00092 18.8 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 ABK71484.1 - 0.073 13.5 0.0 0.073 13.5 0.0 2.1 3 0 0 3 3 3 0 Glycosyl transferases group 1 Lpp-LpqN PF10738.9 ABK71485.1 - 6e-08 32.3 0.1 8.4e-08 31.9 0.1 1.2 1 0 0 1 1 1 1 Probable lipoprotein LpqN HATPase_c PF02518.26 ABK71486.1 - 9.5e-07 29.3 0.1 6.8e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA_3 PF07730.13 ABK71486.1 - 0.17 12.4 7.3 0.14 12.7 3.1 2.5 2 0 0 2 2 2 0 Histidine kinase HTH_17 PF12728.7 ABK71487.1 - 1.7e-13 50.5 0.0 1.9e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 ABK71487.1 - 0.0014 18.4 0.0 0.0035 17.1 0.0 1.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 ABK71487.1 - 0.0087 15.5 0.3 0.046 13.1 0.1 2.0 1 1 1 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.6 ABK71487.1 - 0.017 15.1 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix HTH_22 PF13309.6 ABK71487.1 - 0.023 14.7 0.2 0.038 14.1 0.2 1.3 1 0 0 1 1 1 0 HTH domain HTH_38 PF13936.6 ABK71487.1 - 0.03 14.1 0.0 0.057 13.2 0.0 1.4 2 0 0 2 2 2 0 Helix-turn-helix domain LacI PF00356.21 ABK71487.1 - 0.038 13.8 0.3 0.048 13.4 0.3 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family Soyouz_module PF14313.6 ABK71487.1 - 0.044 13.6 0.0 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 N-terminal region of Paramyxovirinae phosphoprotein (P) HTH_7 PF02796.15 ABK71487.1 - 0.06 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_DeoR PF08220.12 ABK71487.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain AbiEi_4 PF13338.6 ABK71487.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin Sigma70_r4_2 PF08281.12 ABK71487.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 Sigma70_r4 PF04545.16 ABK71487.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 DPM3 PF08285.11 ABK71488.1 - 0.13 12.4 0.3 0.27 11.4 0.3 1.5 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Peptidase_A24 PF01478.18 ABK71489.1 - 5.2e-14 52.6 13.7 1e-13 51.6 13.7 1.6 1 1 0 1 1 1 1 Type IV leader peptidase family HpcH_HpaI PF03328.14 ABK71490.1 - 0.00013 21.2 0.0 0.00014 21.0 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family FCD PF07729.12 ABK71491.1 - 4.6e-21 75.5 4.0 7.6e-21 74.8 4.0 1.3 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 ABK71491.1 - 3.3e-17 61.9 0.4 6.1e-17 61.0 0.4 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 ABK71491.1 - 0.0027 17.7 0.1 0.008 16.2 0.1 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 ABK71491.1 - 0.0031 17.4 0.3 0.015 15.2 0.1 2.2 2 0 0 2 2 2 1 MarR family Rrf2 PF02082.20 ABK71491.1 - 0.0039 17.5 0.0 0.008 16.5 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator HTH_5 PF01022.20 ABK71491.1 - 0.038 13.8 0.0 0.086 12.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_Crp_2 PF13545.6 ABK71491.1 - 0.039 13.9 0.4 0.17 11.9 0.2 2.2 1 1 1 2 2 2 0 Crp-like helix-turn-helix domain HTH_41 PF14502.6 ABK71491.1 - 0.053 13.2 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain tRNA-synt_1b PF00579.25 ABK71492.1 - 2.6e-79 266.6 0.0 3.2e-79 266.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 ABK71492.1 - 0.00029 20.5 0.0 0.00063 19.4 0.0 1.5 1 0 0 1 1 1 1 S4 domain TyrRSs_C PF16714.5 ABK71492.1 - 0.0012 18.6 0.3 0.027 14.3 0.3 2.3 1 1 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain tRNA-synt_1c PF00749.21 ABK71493.1 - 3.2e-44 151.1 0.0 4.1e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Lpp-LpqN PF10738.9 ABK71494.1 - 3.3e-60 202.5 0.0 4.2e-60 202.2 0.0 1.1 1 0 0 1 1 1 1 Probable lipoprotein LpqN adh_short_C2 PF13561.6 ABK71496.1 - 1.4e-57 195.0 7.4 1.5e-57 194.8 7.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK71496.1 - 1.3e-48 165.1 4.7 1.5e-48 164.8 4.7 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK71496.1 - 6e-19 68.6 4.0 8.1e-19 68.2 4.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK71496.1 - 4.6e-07 29.5 3.5 1.8e-06 27.6 3.5 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ABK71496.1 - 3.6e-06 26.3 1.3 4.9e-06 25.9 1.3 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 ABK71496.1 - 4e-05 22.8 0.6 5.3e-05 22.4 0.6 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ABK71496.1 - 0.00074 19.0 0.3 0.0011 18.5 0.3 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 ABK71496.1 - 0.0013 17.9 0.5 0.004 16.4 0.5 1.7 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 ABK71496.1 - 0.0053 16.7 9.7 0.0079 16.1 8.7 1.8 1 1 1 2 2 2 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 ABK71496.1 - 0.0075 15.4 3.2 0.012 14.8 3.2 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 ABK71496.1 - 0.0076 16.5 4.2 0.016 15.4 2.5 2.1 1 1 1 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 ABK71496.1 - 0.012 15.2 3.7 0.032 13.8 3.9 1.6 2 0 0 2 2 2 0 NmrA-like family 3HCDH_N PF02737.18 ABK71496.1 - 0.12 12.2 2.2 0.22 11.4 2.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ribosomal_S11 PF00411.19 ABK71496.1 - 2.5 8.5 7.3 8 6.9 0.4 3.2 2 1 1 3 3 3 0 Ribosomal protein S11 ADH_N PF08240.12 ABK71497.1 - 7.3e-29 99.8 1.1 7.3e-29 99.8 1.1 2.1 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ABK71497.1 - 6.5e-14 52.0 0.6 1.6e-09 37.8 0.4 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ABK71497.1 - 0.00019 20.8 0.4 0.0003 20.1 0.4 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 ABK71497.1 - 0.0035 16.1 0.0 0.0049 15.6 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein ADH_N_assoc PF13823.6 ABK71497.1 - 0.017 15.0 0.1 0.035 14.0 0.1 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated ThiF PF00899.21 ABK71497.1 - 0.064 12.6 0.3 0.12 11.7 0.3 1.4 1 0 0 1 1 1 0 ThiF family XdhC_C PF13478.6 ABK71497.1 - 0.11 13.0 0.2 0.2 12.1 0.2 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain Creatininase PF02633.14 ABK71498.1 - 4.1e-58 196.7 2.0 4.6e-58 196.5 2.0 1.0 1 0 0 1 1 1 1 Creatinine amidohydrolase Beta-lactamase2 PF13354.6 ABK71499.1 - 9.9e-11 41.6 0.0 1.2e-05 25.0 0.0 2.1 1 1 1 2 2 2 2 Beta-lactamase enzyme family Beta-lactamase PF00144.24 ABK71499.1 - 0.00015 21.2 3.1 0.055 12.7 0.0 2.4 1 1 2 3 3 3 2 Beta-lactamase CAP_N PF01213.19 ABK71499.1 - 0.011 15.3 2.8 0.014 14.9 2.8 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Peptidase_S11 PF00768.20 ABK71499.1 - 0.12 11.7 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase MTES_1575 PF18741.1 ABK71500.1 - 3.9e-10 39.8 0.0 6.1e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 REase_MTES_1575 DUF559 PF04480.12 ABK71500.1 - 1.4e-06 28.1 0.0 2.8e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF559) AbiEi_1 PF09407.10 ABK71500.1 - 0.015 15.6 0.0 0.024 15.0 0.0 1.4 1 0 0 1 1 1 0 AbiEi antitoxin C-terminal domain TetR_N PF00440.23 ABK71501.1 - 4.2e-15 55.3 0.3 9.4e-15 54.1 0.3 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 ABK71501.1 - 2.5e-07 31.0 1.3 2.5e-07 31.0 1.3 2.1 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_6 PF13977.6 ABK71501.1 - 6.8e-05 23.1 1.5 6.8e-05 23.1 1.5 2.1 1 1 1 2 2 2 1 BetI-type transcriptional repressor, C-terminal Methyltransf_25 PF13649.6 ABK71502.1 - 2.7e-14 53.6 0.2 7.8e-14 52.2 0.2 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK71502.1 - 2.4e-10 41.0 0.0 4.2e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABK71502.1 - 3e-10 40.6 0.1 5.4e-10 39.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ABK71502.1 - 8e-06 25.5 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 ABK71502.1 - 0.0021 17.9 0.0 0.0028 17.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABK71502.1 - 0.0023 17.8 0.0 0.0033 17.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 ABK71502.1 - 0.019 14.7 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase CinA PF02464.17 ABK71503.1 - 1.3e-43 148.2 1.1 1.6e-43 148.0 1.1 1.0 1 0 0 1 1 1 1 Competence-damaged protein MlaD PF02470.20 ABK71504.1 - 1.1e-15 57.6 0.1 2.5e-15 56.5 0.1 1.6 1 0 0 1 1 1 1 MlaD protein Mce4_CUP1 PF11887.8 ABK71504.1 - 5.5e-06 26.0 2.1 8.4e-06 25.4 2.1 1.3 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative EzrA PF06160.12 ABK71504.1 - 0.08 11.1 0.1 0.1 10.8 0.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Baculo_PEP_C PF04513.12 ABK71504.1 - 0.36 10.9 10.9 1.5 8.9 7.4 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus YSIRK_signal PF04650.17 ABK71504.1 - 1 9.3 2.5 1.9 8.4 2.5 1.4 1 0 0 1 1 1 0 YSIRK type signal peptide ABC_tran PF00005.27 ABK71505.1 - 3.1e-35 121.7 0.0 5e-35 121.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 ABK71505.1 - 1.1e-11 44.7 0.7 3e-11 43.3 0.2 2.1 2 0 0 2 2 2 1 TOBE domain AAA_21 PF13304.6 ABK71505.1 - 6.3e-05 22.9 0.2 0.06 13.1 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ABK71505.1 - 0.00061 20.2 0.3 0.0012 19.3 0.3 1.5 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 ABK71505.1 - 0.002 17.6 0.0 0.75 9.2 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ABK71505.1 - 0.0033 17.9 0.0 0.0047 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ABK71505.1 - 0.0039 17.5 0.4 0.02 15.2 0.4 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ABK71505.1 - 0.014 15.1 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 ABK71505.1 - 0.026 14.7 0.6 0.35 11.0 0.6 2.3 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ABK71505.1 - 0.028 14.1 1.0 0.068 12.9 1.0 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 ABK71505.1 - 0.041 14.3 0.1 0.19 12.2 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 ABK71505.1 - 0.042 14.1 1.7 0.93 9.7 1.7 2.4 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 ABK71505.1 - 0.17 11.8 0.1 0.43 10.5 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase Rad17 PF03215.15 ABK71505.1 - 0.28 11.1 0.0 0.42 10.5 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain MFS_1 PF07690.16 ABK71506.1 - 5.2e-28 98.0 44.8 5.2e-28 98.0 44.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK71506.1 - 4.3e-25 88.5 30.8 3e-19 69.2 7.4 2.1 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 ABK71506.1 - 2.6e-06 26.3 27.8 2.6e-06 26.3 27.8 1.8 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_1_like PF12832.7 ABK71506.1 - 0.00054 18.9 18.2 0.001 18.0 7.6 2.3 1 1 1 2 2 2 2 MFS_1 like family RhodobacterPufX PF11511.8 ABK71506.1 - 0.21 11.2 2.9 2 8.1 0.4 3.1 2 0 0 2 2 2 0 Intrinsic membrane protein PufX ECH_1 PF00378.20 ABK71507.1 - 2.4e-45 154.8 0.0 2.9e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK71507.1 - 1.5e-17 64.1 0.0 1.9e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_C25 PF01364.18 ABK71507.1 - 0.17 11.1 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C25 GATase PF00117.28 ABK71508.1 - 5.3e-19 68.7 0.0 6.6e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 ABK71508.1 - 4.9e-05 23.0 0.0 6.9e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 ABK71508.1 - 0.0019 18.0 0.5 0.0071 16.1 0.5 1.9 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.19 ABK71508.1 - 0.0022 17.9 0.0 0.064 13.1 0.0 2.1 2 0 0 2 2 2 1 SNO glutamine amidotransferase family DUF2793 PF10983.8 ABK71508.1 - 0.17 11.8 4.2 0.66 9.9 0.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2793) DUF1453 PF07301.11 ABK71509.1 - 0.64 10.0 7.5 0.85 9.6 1.4 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1453) UTRA PF07702.13 ABK71510.1 - 6.8e-39 132.9 1.6 9.6e-39 132.5 1.6 1.2 1 0 0 1 1 1 1 UTRA domain GntR PF00392.21 ABK71510.1 - 3.1e-13 49.2 0.5 7.2e-13 48.0 0.1 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 ABK71510.1 - 1.3e-07 31.1 0.6 0.00012 21.5 0.1 2.4 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 ABK71510.1 - 2.3e-06 27.4 1.2 0.00037 20.3 0.3 2.5 2 0 0 2 2 2 1 MarR family MarR PF01047.22 ABK71510.1 - 1.3e-05 25.0 0.1 0.00044 20.1 0.1 2.3 2 0 0 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 ABK71510.1 - 9.8e-05 22.3 2.8 0.00041 20.3 0.2 2.7 3 0 0 3 3 3 1 Crp-like helix-turn-helix domain HTH_36 PF13730.6 ABK71510.1 - 0.00022 21.1 0.0 0.0011 18.9 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_IclR PF09339.10 ABK71510.1 - 0.0011 18.7 2.2 0.0021 17.8 0.2 2.3 2 1 0 2 2 2 1 IclR helix-turn-helix domain HTH_DeoR PF08220.12 ABK71510.1 - 0.0046 16.7 0.2 0.0083 15.8 0.2 1.4 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain TrmB PF01978.19 ABK71510.1 - 0.005 16.7 0.2 0.03 14.2 0.0 2.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Fe_dep_repress PF01325.19 ABK71510.1 - 0.0083 16.3 0.0 0.6 10.4 0.0 2.3 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain Rrf2 PF02082.20 ABK71510.1 - 0.018 15.3 0.2 0.11 12.8 0.0 2.2 3 0 0 3 3 3 0 Transcriptional regulator RP-C PF03428.13 ABK71510.1 - 0.041 13.5 0.1 0.084 12.5 0.1 1.4 1 0 0 1 1 1 0 Replication protein C N-terminal domain HTH_11 PF08279.12 ABK71510.1 - 0.045 13.7 0.4 0.14 12.1 0.1 2.0 2 0 0 2 2 2 0 HTH domain AbiEi_4 PF13338.6 ABK71510.1 - 0.23 11.6 4.2 1.1 9.4 0.0 3.5 3 1 1 4 4 4 0 Transcriptional regulator, AbiEi antitoxin MmgE_PrpD PF03972.14 ABK71511.1 - 3.4e-36 124.7 11.0 4.6e-36 124.3 11.0 1.1 1 0 0 1 1 1 1 MmgE/PrpD family RskA PF10099.9 ABK71512.1 - 0.00087 19.6 5.0 0.0011 19.4 5.0 1.3 1 1 0 1 1 1 1 Anti-sigma-K factor rskA Pro_isomerase PF00160.21 ABK71515.1 - 9.2e-26 91.0 0.0 1.2e-25 90.6 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4190 PF13828.6 ABK71515.1 - 8.8e-17 60.6 4.6 2.2e-16 59.3 4.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4190) Phage_holin_3_6 PF07332.11 ABK71515.1 - 0.093 12.8 2.9 0.15 12.1 2.9 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III MatE PF01554.18 ABK71516.1 - 4.2e-39 133.8 36.7 3.9e-24 85.1 10.1 2.4 3 0 0 3 3 3 2 MatE UPF0052 PF01933.18 ABK71517.1 - 2.4e-65 220.7 0.0 2.8e-65 220.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 AIMP2_LysRS_bd PF16780.5 ABK71517.1 - 0.038 13.7 0.0 0.085 12.6 0.0 1.5 1 0 0 1 1 1 0 AIMP2 lysyl-tRNA synthetase binding domain DUF3046 PF11248.8 ABK71520.1 - 5e-31 106.9 0.1 5.5e-31 106.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3046) DapB_C PF05173.14 ABK71521.1 - 9.4e-32 109.6 0.0 1.4e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus DapB_N PF01113.20 ABK71521.1 - 1.3e-23 83.5 1.8 1.5e-22 80.0 1.8 2.2 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 ABK71521.1 - 0.26 11.7 1.5 0.5 10.8 0.6 2.0 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KfrB PF18790.1 ABK71522.1 - 0.13 12.6 0.0 0.29 11.4 0.0 1.6 2 0 0 2 2 2 0 KfrB protein MLTR_LBD PF17765.1 ABK71523.1 - 9.5e-48 162.5 4.4 9.5e-48 162.5 4.4 1.5 2 0 0 2 2 2 1 MmyB-like transcription regulator ligand binding domain HTH_31 PF13560.6 ABK71523.1 - 2e-16 60.1 7.1 4.1e-16 59.1 7.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 ABK71523.1 - 6.6e-09 35.7 0.0 1.3e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 ABK71523.1 - 0.069 13.6 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Plasmid_stab_B PF10784.9 ABK71523.1 - 0.11 12.3 0.2 22 4.9 0.0 2.5 2 0 0 2 2 2 0 Plasmid stability protein Nitroreductase PF00881.24 ABK71524.1 - 9.9e-28 97.3 0.0 1.3e-27 97.0 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 ABK71524.1 - 0.039 13.5 0.0 1.2 8.6 0.0 2.4 2 1 0 2 2 2 0 Putative TM nitroreductase Cyt_bd_oxida_II PF02322.15 ABK71525.1 - 3.9e-107 358.1 34.9 4.4e-107 357.9 34.9 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II Anoctamin PF04547.12 ABK71525.1 - 0.0007 18.5 2.2 0.00084 18.3 0.7 1.7 2 0 0 2 2 2 1 Calcium-activated chloride channel ADH_zinc_N_2 PF13602.6 ABK71526.1 - 2.8e-18 67.2 0.0 4.4e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ABK71526.1 - 1.6e-15 57.3 0.0 2.7e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ABK71526.1 - 1.1e-10 41.4 0.2 2.5e-09 37.0 0.3 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain HMGL-like PF00682.19 ABK71527.1 - 1.8e-56 191.6 3.8 2.4e-56 191.2 3.8 1.1 1 0 0 1 1 1 1 HMGL-like DmpG_comm PF07836.11 ABK71527.1 - 1.2e-31 108.1 0.3 4.1e-31 106.3 0.3 2.0 1 0 0 1 1 1 1 DmpG-like communication domain DUF4149 PF13664.6 ABK71528.1 - 0.0088 16.3 4.6 0.02 15.2 4.6 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4149) DUF4231 PF14015.6 ABK71528.1 - 0.14 12.6 3.9 0.32 11.5 3.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Acyl-CoA_dh_1 PF00441.24 ABK71529.1 - 1.1e-46 158.7 6.7 1.6e-46 158.2 6.7 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK71529.1 - 1.5e-35 122.3 0.0 3.3e-35 121.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ABK71529.1 - 6.4e-20 71.2 0.1 1.1e-19 70.4 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ABK71529.1 - 7.2e-18 65.1 7.6 1.1e-17 64.5 7.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Pyridox_ox_2 PF12900.7 ABK71530.1 - 8.6e-28 97.1 0.1 1e-27 96.9 0.1 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 ABK71530.1 - 0.078 13.2 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Alpha-amylase PF00128.24 ABK71531.1 - 2.5e-78 264.0 0.0 1.5e-77 261.4 0.0 2.0 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 ABK71531.1 - 3.3e-22 78.4 0.0 6.6e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain GHL5 PF14872.6 ABK71531.1 - 0.012 13.6 0.0 2.7 5.9 0.0 2.1 1 1 1 2 2 2 0 Hypothetical glycoside hydrolase 5 hDGE_amylase PF14701.6 ABK71531.1 - 0.015 14.4 0.0 0.023 13.8 0.0 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Shikimate_dh_N PF08501.11 ABK71532.1 - 5.7e-19 68.2 0.0 1.2e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 ABK71532.1 - 0.00045 20.3 0.1 0.0018 18.3 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase SDH_C PF18317.1 ABK71532.1 - 0.00075 19.2 0.5 0.0018 18.0 0.5 1.7 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain F420_oxidored PF03807.17 ABK71532.1 - 0.0088 16.6 0.1 0.026 15.1 0.1 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Amidohydro_1 PF01979.20 ABK71533.1 - 1.6e-20 73.7 1.2 5.1e-14 52.3 0.2 2.3 1 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 ABK71533.1 - 4.4e-18 66.0 9.3 2.6e-11 43.7 2.6 2.3 1 1 0 2 2 2 2 Amidohydrolase family DUF4129 PF13559.6 ABK71533.1 - 0.55 10.5 0.0 0.55 10.5 0.0 4.1 4 2 1 5 5 5 0 Domain of unknown function (DUF4129) PEP_mutase PF13714.6 ABK71535.1 - 8.2e-50 169.5 1.8 9.7e-50 169.2 1.8 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 ABK71535.1 - 2.9e-12 45.9 0.3 5.1e-12 45.1 0.3 1.4 1 0 0 1 1 1 1 Isocitrate lyase family Epimerase PF01370.21 ABK71536.1 - 8.4e-42 143.3 1.4 3.2e-41 141.4 1.4 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ABK71536.1 - 6.9e-29 101.3 0.0 3.9e-15 56.1 0.0 2.4 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ABK71536.1 - 9.3e-13 47.8 0.0 4.6e-09 35.7 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 ABK71536.1 - 1.3e-08 34.4 0.0 0.0036 16.5 0.1 2.8 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 ABK71536.1 - 9.7e-08 32.1 0.1 2.2e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 ABK71536.1 - 6.8e-06 25.4 0.0 0.0004 19.6 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 ABK71536.1 - 7.9e-06 25.2 0.0 0.0071 15.5 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain adh_short PF00106.25 ABK71536.1 - 0.0018 17.7 0.5 0.3 10.5 0.1 2.3 2 0 0 2 2 2 2 short chain dehydrogenase Rossmann-like PF10727.9 ABK71536.1 - 0.014 15.2 0.4 0.029 14.2 0.4 1.6 1 1 0 1 1 1 0 Rossmann-like domain DFP PF04127.15 ABK71536.1 - 0.19 11.6 0.2 0.31 10.9 0.2 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein UDPG_MGDP_dh_N PF03721.14 ABK71536.1 - 0.22 11.1 0.2 0.35 10.4 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain adh_short_C2 PF13561.6 ABK71536.1 - 0.24 10.9 1.6 3.1 7.3 0.3 2.4 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase AAA PF00004.29 ABK71537.1 - 1e-39 136.0 0.0 2.7e-39 134.6 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ABK71537.1 - 3e-08 33.3 0.0 7.3e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain TPR_20 PF14561.6 ABK71537.1 - 1.4e-05 25.3 0.9 0.0023 18.3 0.7 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_16 PF13191.6 ABK71537.1 - 2.1e-05 24.9 0.2 0.0057 17.1 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 ABK71537.1 - 0.00014 21.7 0.0 0.00025 20.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TPR_19 PF14559.6 ABK71537.1 - 0.00019 21.8 1.0 0.00056 20.4 1.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat AAA_22 PF13401.6 ABK71537.1 - 0.00047 20.4 0.4 0.042 14.1 0.1 2.8 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 ABK71537.1 - 0.00056 19.2 0.0 0.0013 18.0 0.0 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_5 PF07728.14 ABK71537.1 - 0.0006 19.8 0.0 0.0021 18.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 ABK71537.1 - 0.0017 17.8 0.1 0.0043 16.5 0.1 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 ABK71537.1 - 0.003 17.6 0.0 0.0048 16.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 ABK71537.1 - 0.0038 17.4 0.0 0.0067 16.6 0.0 1.4 1 0 0 1 1 1 1 Cytidylate kinase-like family Rad17 PF03215.15 ABK71537.1 - 0.0042 17.0 0.0 0.0066 16.4 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain HrpB1_HrpK PF09613.10 ABK71537.1 - 0.0044 16.7 0.7 0.011 15.4 0.7 1.6 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB1_HrpK) IstB_IS21 PF01695.17 ABK71537.1 - 0.0063 16.3 0.1 0.031 14.0 0.0 2.1 1 1 2 3 3 3 1 IstB-like ATP binding protein MCM PF00493.23 ABK71537.1 - 0.011 14.9 0.0 0.033 13.3 0.0 1.7 2 0 0 2 2 2 0 MCM P-loop domain TPR_16 PF13432.6 ABK71537.1 - 0.013 16.2 1.5 0.013 16.2 1.5 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 ABK71537.1 - 0.014 16.1 5.6 0.022 15.6 0.9 3.7 3 1 1 4 4 3 0 Tetratricopeptide repeat AAA_18 PF13238.6 ABK71537.1 - 0.021 15.4 0.0 0.036 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain TPR_12 PF13424.6 ABK71537.1 - 0.028 14.7 0.5 0.11 12.9 0.5 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_4 PF07721.14 ABK71537.1 - 0.035 14.7 2.2 0.035 14.7 2.2 3.3 3 0 0 3 3 1 0 Tetratricopeptide repeat RNA_helicase PF00910.22 ABK71537.1 - 0.04 14.3 0.0 0.092 13.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TPR_9 PF13371.6 ABK71537.1 - 0.049 13.8 4.4 2.5 8.3 0.7 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 ABK71537.1 - 0.067 13.1 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat AAA_33 PF13671.6 ABK71537.1 - 0.068 13.3 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 ABK71537.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain TPR_2 PF07719.17 ABK71537.1 - 0.12 12.5 0.3 0.32 11.2 0.3 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat AAA_24 PF13479.6 ABK71537.1 - 0.14 11.9 0.1 0.27 10.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain P53_C PF11619.8 ABK71537.1 - 0.16 12.0 0.0 0.41 10.7 0.0 1.6 1 0 0 1 1 1 0 Transcription factor P53 - C terminal domain Parvo_NS1 PF01057.17 ABK71537.1 - 0.19 10.8 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase_2 PF01637.18 ABK71537.1 - 0.22 11.4 0.0 1.7 8.5 0.1 2.0 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 ABK71537.1 - 0.25 10.8 0.0 0.4 10.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Dak1 PF02733.17 ABK71538.1 - 1.8e-131 437.6 0.7 2.1e-131 437.5 0.7 1.0 1 0 0 1 1 1 1 Dak1 domain DUF4213 PF13938.6 ABK71538.1 - 0.25 11.6 2.8 0.6 10.4 1.9 2.2 2 1 0 2 2 2 0 Putative heavy-metal chelation Thiolase_N PF00108.23 ABK71539.1 - 4.3e-63 213.1 1.2 6.6e-63 212.5 0.2 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ABK71539.1 - 4.8e-40 136.0 0.2 4.8e-40 136.0 0.2 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ABK71539.1 - 0.0025 17.4 2.9 0.0038 16.8 1.4 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Nas2_N PF18265.1 ABK71539.1 - 0.12 12.3 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 Nas2 N_terminal domain DUF4079 PF13301.6 ABK71540.1 - 0.35 11.0 10.5 2.1 8.5 0.0 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF4079) DUF485 PF04341.12 ABK71540.1 - 0.64 10.0 0.0 0.64 10.0 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function, DUF485 Zeta_toxin PF06414.12 ABK71541.1 - 5.8e-14 51.8 0.1 1.7e-13 50.3 0.1 1.6 1 1 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 ABK71541.1 - 1e-09 38.7 0.0 1.3e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ABK71541.1 - 0.0064 16.2 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 ABK71541.1 - 0.0067 16.9 0.0 0.0081 16.7 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 ABK71541.1 - 0.023 15.2 0.0 0.027 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 ABK71541.1 - 0.025 14.2 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 ABK71541.1 - 0.11 12.2 0.1 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK71541.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ABK71541.1 - 0.12 12.8 0.0 0.13 12.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain DUF3367 PF11847.8 ABK71542.1 - 2.3e-288 957.7 22.9 2.3e-288 957.7 22.9 1.8 2 0 0 2 2 2 1 Alpha-(1->3)-arabinofuranosyltransferase F5_F8_type_C PF00754.25 ABK71542.1 - 7.6e-11 42.2 0.1 3.7e-05 23.9 0.1 2.6 2 0 0 2 2 2 2 F5/8 type C domain ADH_N PF08240.12 ABK71543.1 - 2.1e-28 98.4 0.4 3.9e-28 97.5 0.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ABK71543.1 - 1.9e-24 86.1 0.8 3.5e-24 85.2 0.8 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ABK71543.1 - 2.2e-11 43.6 1.1 3e-11 43.2 1.1 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 ABK71543.1 - 5.3e-05 24.3 0.1 0.00011 23.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ABK71543.1 - 0.0016 17.7 1.7 0.003 16.9 1.7 1.5 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 ABK71543.1 - 0.0021 16.8 0.3 0.003 16.3 0.3 1.1 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 ABK71543.1 - 0.018 14.2 0.9 0.027 13.6 0.9 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 ABK71543.1 - 0.018 14.3 0.1 0.034 13.4 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 ABK71543.1 - 0.07 13.6 0.4 0.14 12.7 0.4 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 ABK71543.1 - 0.083 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 ABK71543.1 - 0.18 11.0 3.2 0.23 10.7 0.3 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ABK71543.1 - 0.24 10.5 1.9 0.32 10.0 1.9 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 ABK71543.1 - 0.27 10.5 1.2 0.4 10.0 1.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase TetR_N PF00440.23 ABK71544.1 - 5e-19 67.8 0.1 1.3e-18 66.5 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 ABK71544.1 - 9.8e-17 61.3 4.9 9.8e-17 61.3 4.9 2.2 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain HTH_7 PF02796.15 ABK71544.1 - 7.8e-06 25.9 0.0 1.9e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase TetR_C_7 PF14246.6 ABK71544.1 - 0.0015 18.5 0.3 0.0035 17.4 0.1 1.7 2 0 0 2 2 2 1 AefR-like transcriptional repressor, C-terminal domain HTH_23 PF13384.6 ABK71544.1 - 0.0027 17.5 0.7 0.0061 16.3 0.1 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_1_2 PF13022.6 ABK71544.1 - 0.0032 17.6 0.0 0.0066 16.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of insertion element transposase HTH_IclR PF09339.10 ABK71544.1 - 0.013 15.2 0.3 0.074 12.9 0.0 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_28 PF13518.6 ABK71544.1 - 0.025 14.7 0.7 0.29 11.3 0.1 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_29 PF13551.6 ABK71544.1 - 0.067 13.2 3.8 0.14 12.2 0.0 2.9 3 0 0 3 3 3 0 Winged helix-turn helix HTH_35 PF13693.6 ABK71544.1 - 0.095 12.8 0.1 0.3 11.1 0.1 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding CENP-B_N PF04218.13 ABK71544.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain TetR_C_31 PF17940.1 ABK71544.1 - 0.4 10.9 12.3 0.1 12.8 6.3 2.6 1 1 2 3 3 3 0 Tetracyclin repressor-like, C-terminal domain VapB_antitoxin PF09957.9 ABK71544.1 - 1.1 9.3 3.5 3.7 7.6 0.0 2.9 4 0 0 4 4 4 0 Bacterial antitoxin of type II TA system, VapB LCM PF04072.14 ABK71545.1 - 1.2e-66 224.2 0.3 1.5e-66 224.0 0.3 1.1 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase DUF417 PF04224.12 ABK71546.1 - 2.7e-32 111.7 9.3 3.3e-30 104.9 9.3 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF417 DoxX PF07681.12 ABK71547.1 - 6.5e-15 55.5 8.8 6.5e-15 55.5 8.8 1.9 2 0 0 2 2 2 1 DoxX DoxD PF04173.13 ABK71547.1 - 0.056 13.4 0.3 0.056 13.4 0.3 1.6 2 0 0 2 2 2 0 TQO small subunit DoxD DUF5386 PF17360.2 ABK71547.1 - 0.27 11.1 0.1 0.4 10.6 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5386) Maff2 PF12750.7 ABK71547.1 - 4.9 7.1 11.4 5.9 6.8 2.0 2.6 2 0 0 2 2 2 0 Maff2 family CorA PF01544.18 ABK71548.1 - 5.9e-63 212.9 0.1 6.7e-63 212.7 0.1 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein UDPG_MGDP_dh_N PF03721.14 ABK71549.1 - 6.5e-55 185.6 0.0 1.1e-54 184.8 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 ABK71549.1 - 3.5e-31 107.3 0.0 1.1e-30 105.7 0.1 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 ABK71549.1 - 5.8e-29 100.6 0.0 2.2e-27 95.5 0.0 2.8 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain F420_oxidored PF03807.17 ABK71549.1 - 1.9e-06 28.4 0.2 0.018 15.6 0.0 3.6 3 1 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 ABK71549.1 - 4.9e-05 23.6 0.0 0.0019 18.4 0.0 3.0 3 1 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 ABK71549.1 - 0.00048 20.1 0.0 0.004 17.1 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ABK71549.1 - 0.0055 16.0 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ABK71549.1 - 0.037 13.4 0.2 0.43 9.9 0.0 2.5 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 ABK71549.1 - 0.059 13.6 0.7 0.19 12.0 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox PF00070.27 ABK71549.1 - 0.44 11.1 3.5 0.83 10.3 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ABK71550.1 - 4.8e-10 39.5 1.1 4.8e-10 39.5 1.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 ABK71550.1 - 2.9e-07 30.2 0.9 6.6e-07 29.0 0.5 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 ABK71550.1 - 7.2e-07 28.8 2.1 5.2e-06 26.0 2.1 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 ABK71550.1 - 2e-05 24.4 7.2 0.00046 19.9 4.3 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ABK71550.1 - 2.5e-05 23.5 2.5 2.5e-05 23.5 2.5 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 ABK71550.1 - 6.9e-05 22.2 0.1 0.00022 20.5 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ABK71550.1 - 7.4e-05 23.2 0.4 0.00041 20.9 0.6 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ABK71550.1 - 9.1e-05 21.9 0.6 0.00017 21.0 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 ABK71550.1 - 0.00043 19.6 0.2 0.00091 18.5 0.2 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 ABK71550.1 - 0.0012 17.7 0.5 0.0018 17.0 0.5 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 ABK71550.1 - 0.0024 17.0 1.6 0.0036 16.4 1.6 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 ABK71550.1 - 0.034 13.0 0.4 0.051 12.4 0.4 1.2 1 0 0 1 1 1 0 Tryptophan halogenase MCRA PF06100.11 ABK71550.1 - 0.041 12.7 0.1 0.056 12.2 0.1 1.1 1 0 0 1 1 1 0 MCRA family SMI1_KNR4 PF09346.10 ABK71551.1 - 5.3e-13 49.5 0.0 6.7e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.6 ABK71551.1 - 1.3e-09 38.5 0.0 2.8e-09 37.5 0.0 1.6 1 1 0 1 1 1 1 SMI1-KNR4 cell-wall SUKH_5 PF14567.6 ABK71551.1 - 0.0063 16.3 0.0 0.74 9.5 0.0 2.2 2 0 0 2 2 2 2 SMI1-KNR4 cell-wall MlaE PF02405.16 ABK71552.1 - 1.7e-54 184.7 26.3 2.2e-54 184.4 26.3 1.1 1 0 0 1 1 1 1 Permease MlaE UPF0542 PF15086.6 ABK71552.1 - 4 7.4 5.6 18 5.4 1.2 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 Glyoxalase_6 PF18029.1 ABK71553.1 - 3.2e-18 66.5 4.4 8.4e-18 65.1 0.4 2.2 2 0 0 2 2 2 1 Glyoxalase-like domain Pterin_4a PF01329.19 ABK71553.1 - 7.6e-05 22.8 0.0 0.00011 22.3 0.0 1.3 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Bac_luciferase PF00296.20 ABK71554.1 - 6.4e-69 232.8 0.3 7.8e-69 232.5 0.3 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase AAA_lid_6 PF17866.1 ABK71554.1 - 0.17 12.1 0.5 8.5 6.6 0.0 2.7 3 0 0 3 3 3 0 AAA lid domain 3HCDH_N PF02737.18 ABK71555.1 - 7.2e-56 188.9 0.0 1.1e-55 188.3 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 ABK71555.1 - 3.6e-30 104.4 0.0 1.1e-29 102.9 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 ABK71555.1 - 0.00012 22.3 0.0 0.00021 21.5 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 ABK71555.1 - 0.00052 20.0 0.1 0.00099 19.1 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.14 ABK71555.1 - 0.0023 17.5 0.1 0.0037 16.9 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 ABK71555.1 - 0.0039 16.6 0.1 0.0067 15.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 ABK71555.1 - 0.012 15.3 0.1 0.017 14.8 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 ABK71555.1 - 0.026 15.1 0.2 0.069 13.7 0.2 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.25 ABK71555.1 - 0.028 13.9 0.1 0.042 13.3 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase AlaDh_PNT_C PF01262.21 ABK71555.1 - 0.037 13.3 0.3 0.055 12.8 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 ABK71555.1 - 0.04 13.3 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.20 ABK71555.1 - 0.058 13.5 0.1 0.098 12.7 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 ABK71555.1 - 0.083 11.9 0.3 0.12 11.4 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Sacchrp_dh_NADP PF03435.18 ABK71555.1 - 0.12 12.6 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ECH_1 PF00378.20 ABK71556.1 - 8e-45 153.1 0.0 9e-45 152.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK71556.1 - 6.8e-27 94.8 0.1 9.7e-27 94.3 0.1 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase V_ATPase_I_N PF18670.1 ABK71556.1 - 0.023 15.1 0.2 2.2 8.7 0.1 2.6 2 0 0 2 2 2 0 V-type ATPase subunit I, N-terminal domain Pyr_redox_2 PF07992.14 ABK71557.1 - 2.6e-27 95.8 0.2 8.2e-27 94.2 0.2 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 ABK71557.1 - 2.5e-20 72.3 0.0 4e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 ABK71557.1 - 7.9e-11 42.0 1.2 7.2e-10 39.0 0.1 2.9 4 0 0 4 4 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ABK71557.1 - 1.4e-10 41.5 0.0 3e-05 24.5 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ABK71557.1 - 5.2e-09 35.9 0.2 5.2e-09 35.9 0.2 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 ABK71557.1 - 2.4e-07 30.3 0.0 0.0019 17.5 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ABK71557.1 - 6.3e-07 29.1 0.1 6.3e-07 29.1 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ABK71557.1 - 9.2e-07 27.9 0.1 2.9e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 ABK71557.1 - 1.1e-06 28.1 0.0 0.024 13.9 0.0 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 ABK71557.1 - 1.6e-06 27.9 9.7 2e-05 24.3 0.3 2.7 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 ABK71557.1 - 7.6e-06 26.3 0.1 0.016 15.6 0.1 2.5 2 0 0 2 2 2 2 Putative NAD(P)-binding FAD_binding_3 PF01494.19 ABK71557.1 - 4.1e-05 23.0 0.1 4.1e-05 23.0 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 ABK71557.1 - 4.2e-05 22.8 0.3 4.2e-05 22.8 0.3 2.4 3 0 0 3 3 3 1 FAD binding domain 2-Hacid_dh_C PF02826.19 ABK71557.1 - 0.00021 20.7 0.0 0.022 14.1 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 ABK71557.1 - 0.00045 20.3 2.0 0.9 9.6 0.1 3.1 2 1 1 3 3 3 2 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FMO-like PF00743.19 ABK71557.1 - 0.00092 17.7 0.0 0.0063 15.0 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like 3HCDH_N PF02737.18 ABK71557.1 - 0.0018 18.2 0.0 0.0059 16.5 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 ABK71557.1 - 0.0028 16.9 1.0 0.0043 16.3 0.0 1.8 2 0 0 2 2 2 1 Thi4 family YjeF_N PF03853.15 ABK71557.1 - 0.0037 17.2 3.1 0.07 13.0 0.2 2.5 1 1 1 2 2 2 1 YjeF-related protein N-terminus GIDA PF01134.22 ABK71557.1 - 0.0053 15.9 0.2 0.0053 15.9 0.2 2.2 2 1 0 2 2 2 1 Glucose inhibited division protein A TrkA_N PF02254.18 ABK71557.1 - 0.015 15.6 0.0 0.44 10.8 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain F420_oxidored PF03807.17 ABK71557.1 - 0.017 15.7 0.0 0.51 10.9 0.0 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 ABK71557.1 - 0.017 14.8 0.0 0.036 13.7 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA K_oxygenase PF13434.6 ABK71557.1 - 0.018 14.2 0.4 2 7.5 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_Gly3P_dh_N PF01210.23 ABK71557.1 - 0.018 15.0 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.12 ABK71557.1 - 0.024 13.7 0.3 0.05 12.7 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 ABK71557.1 - 0.083 12.9 0.2 0.083 12.9 0.2 2.4 3 1 0 3 3 2 0 FAD-NAD(P)-binding Shikimate_DH PF01488.20 ABK71557.1 - 0.086 12.9 0.0 2.8 8.0 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 ABK71557.1 - 0.12 12.5 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 ABK71557.1 - 0.14 11.7 0.1 0.14 11.7 0.1 1.6 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Trp_halogenase PF04820.14 ABK71557.1 - 0.54 9.1 0.0 0.54 9.1 0.0 2.1 3 0 0 3 3 3 0 Tryptophan halogenase ROK PF00480.20 ABK71558.1 - 1.1e-16 61.1 0.0 1.8e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 ROK family HTH_24 PF13412.6 ABK71558.1 - 0.00039 19.9 0.1 0.0026 17.3 0.1 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 ABK71558.1 - 0.0016 18.4 0.0 0.0043 17.0 0.0 1.7 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 ABK71558.1 - 0.0052 16.7 2.9 0.013 15.4 0.9 2.4 2 0 0 2 2 2 1 MarR family HTH_20 PF12840.7 ABK71558.1 - 0.095 12.8 1.2 0.63 10.2 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain DprA_WH PF17782.1 ABK71558.1 - 0.097 12.8 0.3 0.097 12.8 0.3 2.5 3 0 0 3 3 3 0 DprA winged helix domain AA_permease PF00324.21 ABK71559.1 - 2e-43 148.7 48.6 2.4e-43 148.4 48.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ABK71559.1 - 4.4e-41 141.1 49.1 6e-41 140.7 49.1 1.1 1 0 0 1 1 1 1 Amino acid permease CrgA PF06781.12 ABK71559.1 - 0.97 9.5 0.0 0.97 9.5 0.0 4.1 5 0 0 5 5 5 0 Cell division protein CrgA DUF3493 PF11998.8 ABK71559.1 - 2.2 8.5 0.0 2.2 8.5 0.0 3.8 4 0 0 4 4 4 0 Low psii accumulation1 / Rep27 PTH2 PF01981.16 ABK71560.1 - 4e-07 30.3 0.7 0.003 17.8 0.2 2.2 1 1 1 2 2 2 2 Peptidyl-tRNA hydrolase PTH2 DUF4115 PF13464.6 ABK71560.1 - 0.14 12.3 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4115) G_glu_transpept PF01019.21 ABK71561.1 - 2e-105 353.5 3.3 4.4e-105 352.4 3.3 1.5 1 1 0 1 1 1 1 Gamma-glutamyltranspeptidase GtrA PF04138.14 ABK71562.1 - 2.7e-22 79.2 5.7 3.6e-22 78.8 5.7 1.2 1 0 0 1 1 1 1 GtrA-like protein AAA_18 PF13238.6 ABK71563.1 - 1.5e-06 28.7 0.0 6.1e-06 26.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ABK71563.1 - 4.1e-05 23.8 1.4 0.0002 21.5 0.4 2.3 2 1 0 2 2 2 1 AAA domain PRK PF00485.18 ABK71563.1 - 8.6e-05 22.4 0.0 0.00012 21.9 0.0 1.4 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family MeaB PF03308.16 ABK71563.1 - 0.00027 20.0 0.0 0.00037 19.6 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_17 PF13207.6 ABK71563.1 - 0.0065 16.9 0.1 0.28 11.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ABK71563.1 - 0.0076 16.7 0.1 0.011 16.2 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 ABK71563.1 - 0.013 15.4 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain APS_kinase PF01583.20 ABK71563.1 - 0.017 15.1 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_25 PF13481.6 ABK71563.1 - 0.018 14.6 1.3 0.76 9.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain CoaE PF01121.20 ABK71563.1 - 0.021 14.5 0.0 0.069 12.8 0.0 1.8 2 0 0 2 2 2 0 Dephospho-CoA kinase KTI12 PF08433.10 ABK71563.1 - 0.035 13.6 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_28 PF13521.6 ABK71563.1 - 0.041 14.1 0.2 0.12 12.7 0.1 2.1 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ABK71563.1 - 0.068 12.4 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 ABK71563.1 - 0.17 12.1 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_PrkA PF08298.11 ABK71563.1 - 0.18 10.7 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 PrkA AAA domain Amidohydro_2 PF04909.14 ABK71564.1 - 1.8e-17 64.1 0.1 2.7e-17 63.5 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase DSBA PF01323.20 ABK71565.1 - 1.1e-12 48.2 0.9 2.3e-11 43.8 0.9 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_5 PF13743.6 ABK71565.1 - 0.15 11.7 0.1 0.41 10.3 0.1 1.7 1 1 0 1 1 1 0 Thioredoxin DctP PF03480.13 ABK71565.1 - 0.15 11.3 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 3Beta_HSD PF01073.19 ABK71566.1 - 7.3e-60 202.3 0.0 9.2e-60 202.0 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ABK71566.1 - 1.2e-29 103.5 0.1 1.7e-29 103.0 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ABK71566.1 - 7.8e-19 68.2 0.0 1.3e-18 67.5 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 ABK71566.1 - 4.8e-18 65.7 0.3 6.6e-18 65.2 0.3 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 ABK71566.1 - 2.5e-13 49.8 0.0 3.2e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 ABK71566.1 - 4.5e-12 45.7 0.8 8.1e-08 31.7 0.1 2.2 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 ABK71566.1 - 1.3e-09 37.6 0.6 3.7e-07 29.6 1.5 2.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 ABK71566.1 - 1.7e-09 37.6 0.8 2.9e-09 36.8 0.8 1.4 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 ABK71566.1 - 1.6e-06 28.1 2.3 0.00019 21.4 0.2 2.2 2 0 0 2 2 2 2 KR domain adh_short PF00106.25 ABK71566.1 - 0.0013 18.2 0.3 0.0026 17.2 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_2 PF03446.15 ABK71566.1 - 0.091 12.9 0.0 0.23 11.6 0.0 1.7 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase PfkB PF00294.24 ABK71567.1 - 7.2e-30 104.3 2.7 1.2e-29 103.6 2.7 1.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase PGM_PMM_I PF02878.16 ABK71567.1 - 0.0045 16.7 0.1 0.64 9.7 0.0 2.4 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I YAcAr PF10686.9 ABK71567.1 - 0.068 13.1 1.0 0.16 12.0 0.4 2.0 2 0 0 2 2 2 0 YspA, cpYpsA-related SLOG family Methyltransf_34 PF11312.8 ABK71567.1 - 0.31 10.3 0.4 1.5 8.0 0.4 1.9 1 1 0 1 1 1 0 Putative SAM-dependent methyltransferase MDMPI_N PF11716.8 ABK71568.1 - 1.9e-28 99.9 22.2 1.9e-28 99.9 22.2 1.7 2 0 0 2 2 2 1 Mycothiol maleylpyruvate isomerase N-terminal domain Wyosine_form PF08608.12 ABK71568.1 - 6.2e-10 39.3 0.0 1.2e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Wyosine base formation DinB_2 PF12867.7 ABK71568.1 - 1.6e-09 38.3 6.0 1.6e-09 38.3 6.0 2.1 1 1 0 2 2 2 1 DinB superfamily Peptidase_M78 PF06114.13 ABK71568.1 - 0.0087 16.0 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 IrrE N-terminal-like domain DinB PF05163.12 ABK71568.1 - 0.026 14.5 0.1 0.12 12.3 0.1 2.0 1 1 1 2 2 2 0 DinB family TetR_C_11 PF16859.5 ABK71569.1 - 3.4e-30 104.7 1.2 3.4e-30 104.7 1.2 1.7 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK71569.1 - 1.5e-08 34.3 0.6 2.3e-08 33.7 0.0 1.6 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_7 PF14246.6 ABK71569.1 - 6.3e-05 23.0 0.2 9.7e-05 22.4 0.2 1.3 1 0 0 1 1 1 1 AefR-like transcriptional repressor, C-terminal domain HTH_7 PF02796.15 ABK71569.1 - 0.0075 16.3 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase TetR_C_31 PF17940.1 ABK71569.1 - 0.013 15.6 1.1 0.013 15.6 1.1 2.0 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HTH_23 PF13384.6 ABK71569.1 - 0.021 14.6 0.0 0.049 13.4 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_1_2 PF13022.6 ABK71569.1 - 0.042 14.0 0.0 0.083 13.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase TetR_C_21 PF17926.1 ABK71569.1 - 0.054 13.6 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HTH_31 PF13560.6 ABK71569.1 - 0.073 13.4 2.1 2.7 8.4 0.7 3.3 3 1 0 3 3 3 0 Helix-turn-helix domain HTH_3 PF01381.22 ABK71569.1 - 0.076 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix HTH_17 PF12728.7 ABK71569.1 - 0.079 13.2 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain TetR_C_3 PF08362.11 ABK71569.1 - 0.18 11.7 0.0 0.29 11.1 0.0 1.2 1 0 0 1 1 1 0 YcdC-like protein, C-terminal region ADH_zinc_N PF00107.26 ABK71570.1 - 6.9e-28 97.2 0.0 1.2e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ABK71570.1 - 5.3e-27 93.9 3.1 1.3e-26 92.6 3.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 ABK71570.1 - 2.3e-07 30.5 0.0 3.8e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 ABK71570.1 - 2.1e-06 28.9 0.0 4.4e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ABK71570.1 - 0.0098 15.2 1.1 0.018 14.4 0.8 1.5 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.16 ABK71571.1 - 7.5e-41 140.2 56.9 1.1e-24 87.1 35.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK71571.1 - 4.1e-23 82.0 11.8 4.1e-23 82.0 11.8 3.0 1 1 2 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 ABK71571.1 - 0.0087 14.4 4.4 0.32 9.2 0.7 2.7 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_4 PF06779.14 ABK71571.1 - 0.035 13.4 33.1 0.037 13.3 6.5 2.5 1 1 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB Tail_VII PF17091.5 ABK71571.1 - 2.4 8.1 6.2 0.5 10.3 0.3 3.0 3 0 0 3 3 3 0 Inovirus G7P protein MFS_2 PF13347.6 ABK71571.1 - 3.4 6.1 32.4 0.57 8.7 13.4 3.9 1 1 2 3 3 3 0 MFS/sugar transport protein MlaE PF02405.16 ABK71572.1 - 1.3e-55 188.4 32.1 1.6e-55 188.0 32.1 1.1 1 0 0 1 1 1 1 Permease MlaE Methyltransf_23 PF13489.6 ABK71573.1 - 2.1e-15 57.0 0.0 2.8e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABK71573.1 - 5.5e-12 46.2 0.0 1e-11 45.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABK71573.1 - 2.1e-11 44.3 0.0 3.7e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABK71573.1 - 1.7e-07 31.1 0.0 2.3e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK71573.1 - 1.4e-06 29.0 0.0 2.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ABK71573.1 - 3.4e-06 26.7 0.0 4.9e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 ABK71573.1 - 0.00056 19.9 0.0 0.00082 19.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 ABK71573.1 - 0.00068 19.3 0.0 0.00094 18.8 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW FtsJ PF01728.19 ABK71573.1 - 0.0046 17.1 0.0 0.0064 16.6 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 ABK71573.1 - 0.0074 15.6 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Ubie_methyltran PF01209.18 ABK71573.1 - 0.042 13.2 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family RrnaAD PF00398.20 ABK71573.1 - 0.088 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CotH PF08757.11 ABK71574.1 - 2.2e-29 103.0 0.0 3.5e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 CotH kinase protein Collagen PF01391.18 ABK71574.1 - 0.7 9.7 40.8 1.6 8.6 40.8 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) UPF0061 PF02696.14 ABK71576.1 - 5.4e-114 381.5 0.0 1.1e-112 377.3 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family DUF1059 PF06348.11 ABK71576.1 - 0.039 14.2 0.3 0.08 13.2 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1059) DHDPS PF00701.22 ABK71577.1 - 1.1e-53 181.9 0.0 1.3e-53 181.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DHquinase_II PF01220.19 ABK71579.1 - 2.6e-61 205.3 0.5 2.9e-61 205.1 0.5 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Oxidored_nitro PF00148.19 ABK71579.1 - 0.00075 18.3 0.1 0.00087 18.1 0.1 1.1 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase AurF PF11583.8 ABK71579.1 - 0.017 14.4 0.2 0.02 14.2 0.2 1.2 1 0 0 1 1 1 0 P-aminobenzoate N-oxygenase AurF Flavodoxin_2 PF02525.17 ABK71580.1 - 1.6e-23 83.5 0.0 1.9e-23 83.2 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 ABK71580.1 - 2.1e-10 40.5 0.0 2.7e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase BTG PF07742.12 ABK71580.1 - 0.073 12.9 0.1 0.23 11.3 0.1 1.8 1 1 0 1 1 1 0 BTG family ADH_N PF08240.12 ABK71581.1 - 2e-31 108.1 0.1 4.2e-31 107.0 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ABK71581.1 - 4.5e-28 97.8 2.6 7.7e-28 97.1 2.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ABK71581.1 - 2.9e-07 31.6 0.1 5.7e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ABK71581.1 - 9.1e-05 21.9 5.1 0.00014 21.3 5.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ABK71581.1 - 0.00017 21.0 0.2 0.0004 19.8 0.2 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 ABK71581.1 - 0.0037 17.9 0.5 0.013 16.2 0.4 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK71581.1 - 0.017 15.9 0.0 0.035 14.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ELFV_dehydrog PF00208.21 ABK71581.1 - 0.024 14.3 1.2 0.035 13.8 1.2 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Methyltransf_11 PF08241.12 ABK71581.1 - 0.066 13.9 0.2 0.23 12.1 0.2 1.9 1 1 1 2 2 2 0 Methyltransferase domain 3HCDH_N PF02737.18 ABK71581.1 - 0.24 11.3 2.3 0.39 10.6 2.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ABC_tran PF00005.27 ABK71582.1 - 2e-44 151.4 0.0 4.8e-21 75.7 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ABK71582.1 - 5.1e-17 62.6 0.4 0.003 17.4 0.0 4.1 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK71582.1 - 1.2e-11 44.5 0.0 0.00097 18.6 0.0 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ABK71582.1 - 1.9e-10 40.3 0.3 0.00015 21.4 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 ABK71582.1 - 1.8e-06 28.6 0.0 0.09 13.3 0.0 2.1 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 ABK71582.1 - 8.6e-06 25.3 0.0 0.1 12.0 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 ABK71582.1 - 3.1e-05 24.3 0.2 0.16 12.3 0.1 3.3 3 1 0 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 ABK71582.1 - 3.2e-05 23.9 0.0 0.13 12.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 ABK71582.1 - 0.00011 22.6 5.4 0.055 13.9 0.6 2.8 2 2 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 ABK71582.1 - 0.00012 22.0 0.7 0.028 14.3 0.1 2.4 2 0 0 2 2 2 1 NACHT domain IstB_IS21 PF01695.17 ABK71582.1 - 0.00017 21.4 0.5 0.11 12.2 0.0 3.0 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_33 PF13671.6 ABK71582.1 - 0.00065 19.9 1.9 0.11 12.6 0.1 3.3 3 1 0 3 3 3 1 AAA domain NTPase_1 PF03266.15 ABK71582.1 - 0.00083 19.3 0.1 1.7 8.5 0.0 3.3 3 0 0 3 3 3 1 NTPase AAA_28 PF13521.6 ABK71582.1 - 0.00087 19.6 0.7 0.083 13.1 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.6 ABK71582.1 - 0.0011 18.6 12.1 0.14 11.7 3.0 3.9 2 2 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 ABK71582.1 - 0.0023 18.1 0.5 7.8 6.8 0.1 3.8 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 ABK71582.1 - 0.0036 17.1 0.2 3.3 7.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 ABK71582.1 - 0.0044 17.0 2.2 0.5 10.4 0.1 3.3 3 1 1 4 4 4 1 AAA domain (dynein-related subfamily) AAA_27 PF13514.6 ABK71582.1 - 0.0083 15.7 0.1 0.13 11.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 ABK71582.1 - 0.0084 15.5 0.1 0.14 11.5 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_30 PF13604.6 ABK71582.1 - 0.011 15.5 1.5 3.1 7.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 ABK71582.1 - 0.011 16.2 2.3 1.5 9.4 0.4 3.1 3 1 0 3 3 3 0 AAA domain T2SSE PF00437.20 ABK71582.1 - 0.02 14.0 0.1 4.7 6.2 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein RNA_helicase PF00910.22 ABK71582.1 - 0.021 15.2 0.1 2.7 8.4 0.0 2.3 2 0 0 2 2 2 0 RNA helicase KdpD PF02702.17 ABK71582.1 - 0.035 13.6 0.0 3 7.3 0.0 2.2 2 0 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain DUF815 PF05673.13 ABK71582.1 - 0.047 12.8 0.3 0.41 9.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_15 PF13175.6 ABK71582.1 - 0.061 13.0 0.0 21 4.7 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain APS_kinase PF01583.20 ABK71582.1 - 0.066 13.1 0.1 13 5.7 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_7 PF12775.7 ABK71582.1 - 0.067 12.7 0.1 2.3 7.7 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region MukB PF04310.12 ABK71582.1 - 0.083 12.7 0.8 0.31 10.8 0.1 1.9 2 0 0 2 2 2 0 MukB N-terminal G-alpha PF00503.20 ABK71582.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit MMR_HSR1 PF01926.23 ABK71582.1 - 0.12 12.5 0.5 1.4 9.0 0.0 2.6 3 0 0 3 3 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 ABK71582.1 - 0.13 11.6 0.5 4.9 6.4 0.1 2.2 2 0 0 2 2 2 0 Zeta toxin Sigma54_activat PF00158.26 ABK71582.1 - 0.14 11.8 0.0 20 4.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain cobW PF02492.19 ABK71582.1 - 0.33 10.5 2.0 14 5.2 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 ABK71582.1 - 0.34 11.3 1.4 19 5.7 0.1 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) MlaE PF02405.16 ABK71583.1 - 4.5e-53 180.1 23.4 5.9e-53 179.7 23.4 1.1 1 0 0 1 1 1 1 Permease MlaE FAD_binding_3 PF01494.19 ABK71584.1 - 3.4e-18 66.0 0.0 4.3e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ABK71584.1 - 1.4e-11 44.6 1.3 9.9e-05 22.1 0.1 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 ABK71584.1 - 2e-09 36.9 0.0 0.00036 19.5 0.0 2.2 1 1 0 2 2 2 2 Tryptophan halogenase FAD_oxidored PF12831.7 ABK71584.1 - 2.9e-07 30.2 1.6 5.7e-07 29.2 1.6 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 ABK71584.1 - 5.1e-07 29.1 0.3 0.00016 20.9 0.1 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 ABK71584.1 - 1e-06 28.3 0.2 0.00097 18.5 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ABK71584.1 - 1.3e-06 27.4 0.1 0.00011 21.0 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 ABK71584.1 - 1.6e-05 24.2 0.7 0.00032 19.9 0.2 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 ABK71584.1 - 2.1e-05 24.7 0.3 5.3e-05 23.4 0.1 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ABK71584.1 - 0.00068 20.2 0.0 0.072 13.7 0.0 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ABK71584.1 - 0.0028 16.7 1.8 0.022 13.8 0.8 2.5 2 1 0 2 2 2 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 ABK71584.1 - 0.0053 16.1 0.1 0.0082 15.5 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 ABK71584.1 - 0.016 14.4 0.0 0.041 13.1 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 ABK71584.1 - 0.03 13.6 0.1 0.052 12.8 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_trans_4_4 PF13579.6 ABK71584.1 - 0.041 14.3 0.5 0.22 11.9 0.1 2.1 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain DUF1794 PF08768.11 ABK71585.1 - 3.5e-45 153.6 0.0 3.9e-45 153.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) ECH_1 PF00378.20 ABK71586.1 - 6.2e-43 146.9 0.5 7.1e-43 146.7 0.5 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK71586.1 - 1.1e-27 97.4 0.3 1.2e-27 97.3 0.3 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Pyr_redox_2 PF07992.14 ABK71587.1 - 1.6e-59 201.6 1.3 2.2e-59 201.1 1.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ABK71587.1 - 5.3e-14 52.5 1.7 8.3e-08 32.7 0.3 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ABK71587.1 - 2.9e-09 36.5 1.4 0.0046 16.1 0.1 4.0 3 1 1 4 4 4 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 ABK71587.1 - 2.9e-05 24.2 0.4 0.00059 20.0 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ABK71587.1 - 0.00013 21.7 3.5 1.8 8.1 0.1 3.7 4 0 0 4 4 4 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ABK71587.1 - 0.00036 19.9 0.1 0.011 15.0 0.0 2.4 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 ABK71587.1 - 0.0014 17.8 1.3 0.0023 17.1 0.1 2.0 2 1 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 ABK71587.1 - 0.0042 16.4 0.1 0.085 12.1 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 ABK71587.1 - 0.0045 16.3 0.0 3.9 6.6 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Tricorn_PDZ PF14685.6 ABK71587.1 - 0.013 15.5 0.0 0.03 14.3 0.0 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain NAD_binding_9 PF13454.6 ABK71587.1 - 0.017 15.1 1.1 3.9 7.5 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding Amino_oxidase PF01593.24 ABK71587.1 - 0.018 14.4 2.9 1.2 8.4 0.1 3.4 2 1 0 3 3 3 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 ABK71587.1 - 0.019 14.3 0.7 0.049 12.9 0.0 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 ABK71587.1 - 0.041 12.6 1.8 0.31 9.7 0.0 2.8 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_7 PF13241.6 ABK71587.1 - 0.048 14.1 0.9 0.12 12.8 0.0 2.2 3 0 0 3 3 3 0 Putative NAD(P)-binding ApbA PF02558.16 ABK71587.1 - 0.059 13.0 0.1 0.22 11.2 0.1 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DUF732 PF05305.14 ABK71587.1 - 0.087 13.2 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF732) FAD_oxidored PF12831.7 ABK71587.1 - 0.11 11.9 2.7 0.19 11.0 0.1 2.3 3 0 0 3 3 3 0 FAD dependent oxidoreductase DUF948 PF06103.11 ABK71588.1 - 0.0058 16.9 1.7 0.018 15.3 1.0 1.9 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.9 ABK71588.1 - 0.0077 16.5 0.0 0.013 15.8 0.0 1.3 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 ABK71588.1 - 0.033 14.2 0.9 0.048 13.7 0.9 1.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 ABK71588.1 - 0.11 12.5 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DegS PF05384.11 ABK71588.1 - 0.12 11.9 0.4 5 6.6 0.2 2.2 1 1 1 2 2 2 0 Sensor protein DegS TetR_C_33 PF13305.6 ABK71589.1 - 1.1e-18 67.9 3.4 1.6e-18 67.3 3.4 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK71589.1 - 2.9e-05 23.8 0.0 5.3e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family FCD PF07729.12 ABK71590.1 - 2.4e-26 92.6 17.1 3.8e-26 92.0 17.1 1.3 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 ABK71590.1 - 5.1e-16 58.1 0.2 1.2e-15 56.9 0.2 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family FaeA PF04703.12 ABK71590.1 - 0.026 14.9 0.0 0.05 14.0 0.0 1.4 1 0 0 1 1 1 0 FaeA-like protein LexA_DNA_bind PF01726.16 ABK71590.1 - 0.063 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 LexA DNA binding domain TrmB PF01978.19 ABK71590.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Peripla_BP_2 PF01497.18 ABK71591.1 - 7.9e-30 104.2 0.2 9.6e-30 103.9 0.2 1.1 1 0 0 1 1 1 1 Periplasmic binding protein DUF3558 PF12079.8 ABK71593.1 - 1.3e-37 129.5 0.2 1.5e-37 129.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3558) AMP-binding PF00501.28 ABK71594.1 - 1.9e-61 208.0 0.1 5.2e-41 140.6 0.1 2.0 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 ABK71594.1 - 6e-12 46.4 0.0 1.2e-11 45.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TetR_N PF00440.23 ABK71595.1 - 2.2e-09 36.9 0.0 5e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_29 PF17938.1 ABK71595.1 - 0.014 15.5 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF1858 PF08984.11 ABK71595.1 - 0.15 12.2 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1858) ACP_syn_III_C PF08541.10 ABK71596.1 - 6.3e-16 58.3 0.1 1.6e-15 57.1 0.1 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 ABK71596.1 - 1e-09 38.1 0.3 2.1e-09 37.1 0.3 1.5 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 ABK71596.1 - 0.00092 18.6 1.5 0.071 12.5 0.2 2.1 2 0 0 2 2 2 2 Thiolase, N-terminal domain HNH_5 PF14279.6 ABK71597.1 - 2.1e-08 33.9 0.1 3.5e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 HNH endonuclease HNH PF01844.23 ABK71597.1 - 2.9e-08 33.8 0.2 4.6e-08 33.1 0.2 1.3 1 0 0 1 1 1 1 HNH endonuclease HNH_4 PF13395.6 ABK71597.1 - 0.009 15.9 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease DUF883 PF05957.13 ABK71597.1 - 5.4 7.7 7.5 2.2 8.9 0.2 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Bac_luciferase PF00296.20 ABK71598.1 - 4.4e-54 184.0 8.1 3.9e-53 180.9 3.0 2.1 1 1 1 2 2 2 2 Luciferase-like monooxygenase GGDEF_2 PF17853.1 ABK71598.1 - 0.042 14.1 1.5 0.1 12.9 0.2 2.2 2 0 0 2 2 2 0 GGDEF-like domain p450 PF00067.22 ABK71599.1 - 3.9e-26 91.8 0.0 2.6e-22 79.2 0.0 3.1 2 1 0 2 2 2 2 Cytochrome P450 DUF488 PF04343.13 ABK71600.1 - 6.9e-28 97.7 0.0 7.7e-28 97.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF488 EF-hand_14 PF17959.1 ABK71600.1 - 0.033 14.5 0.0 0.041 14.2 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain Barstar PF01337.18 ABK71601.1 - 3.9e-16 58.8 0.0 4.5e-16 58.6 0.0 1.0 1 0 0 1 1 1 1 Barstar (barnase inhibitor) Nitroreductase PF00881.24 ABK71602.1 - 3.1e-10 40.4 1.0 8.9e-06 25.9 0.0 3.2 2 1 1 3 3 3 3 Nitroreductase family TM1586_NiRdase PF14512.6 ABK71602.1 - 0.00046 19.8 0.0 0.082 12.5 0.0 2.2 2 0 0 2 2 2 2 Putative TM nitroreductase Ribosomal_L34 PF00468.17 ABK71603.1 - 6.2e-19 67.7 12.4 7e-19 67.5 12.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L34 TPR_MalT PF17874.1 ABK71604.1 - 1.1e-13 51.3 6.0 1.1e-13 51.3 6.0 2.1 3 0 0 3 3 3 1 MalT-like TPR region GerE PF00196.19 ABK71604.1 - 8.8e-13 47.6 0.2 1.8e-12 46.6 0.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family TPR_2 PF07719.17 ABK71604.1 - 4.5e-06 26.4 7.5 0.012 15.7 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 ABK71604.1 - 5.9e-06 26.5 3.9 5.9e-06 26.5 3.9 4.0 5 0 0 5 5 4 1 Tetratricopeptide repeat AAA_16 PF13191.6 ABK71604.1 - 5.1e-05 23.7 2.1 0.00028 21.3 0.3 3.0 2 1 0 2 2 2 1 AAA ATPase domain TPR_16 PF13432.6 ABK71604.1 - 5.2e-05 23.8 12.7 0.00021 21.8 1.6 6.1 3 1 3 6 6 5 3 Tetratricopeptide repeat HTH_23 PF13384.6 ABK71604.1 - 0.0088 15.8 0.2 0.098 12.5 0.2 2.9 1 0 0 1 1 1 1 Homeodomain-like domain TPR_8 PF13181.6 ABK71604.1 - 0.0091 16.1 0.2 6 7.3 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_25 PF13481.6 ABK71604.1 - 0.021 14.4 2.7 0.12 12.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain TPR_11 PF13414.6 ABK71604.1 - 0.039 13.6 0.1 0.3 10.8 0.0 2.7 3 0 0 3 3 3 0 TPR repeat TPR_19 PF14559.6 ABK71604.1 - 0.042 14.4 0.3 0.042 14.4 0.3 3.9 4 1 2 6 6 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 ABK71604.1 - 0.088 12.7 0.2 0.088 12.7 0.2 4.9 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 ABK71604.1 - 0.097 13.3 0.1 0.097 13.3 0.1 8.2 7 1 1 8 8 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 ABK71604.1 - 0.12 13.3 31.9 0.29 12.1 0.1 7.7 7 2 1 8 8 8 0 Tetratricopeptide repeat Sigma70_r4 PF04545.16 ABK71604.1 - 0.19 11.3 3.3 0.28 10.7 0.9 2.5 3 0 0 3 3 3 0 Sigma-70, region 4 Peptidase_C26 PF07722.13 ABK71605.1 - 2.7e-53 180.9 0.0 3e-53 180.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase C26 GATase PF00117.28 ABK71605.1 - 2.3e-15 56.9 0.0 4e-15 56.1 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DoxX PF07681.12 ABK71606.1 - 1e-05 26.0 6.6 2.2e-05 25.0 6.6 1.6 1 0 0 1 1 1 1 DoxX DoxX_3 PF13781.6 ABK71606.1 - 0.16 12.6 7.6 0.099 13.3 4.4 2.1 1 1 1 2 2 2 0 DoxX-like family BPD_transp_1 PF00528.22 ABK71607.1 - 6.1e-26 91.3 11.6 6.1e-26 91.3 11.6 1.5 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Romo1 PF10247.9 ABK71607.1 - 0.083 13.3 2.8 0.13 12.7 0.5 2.5 4 0 0 4 4 4 0 Reactive mitochondrial oxygen species modulator 1 DEAD PF00270.29 ABK71608.1 - 8.7e-48 162.4 0.0 1.1e-46 158.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ABK71608.1 - 2e-31 108.6 0.0 2e-30 105.4 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ABK71608.1 - 0.0011 19.0 0.0 0.0024 17.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 ABK71608.1 - 0.036 13.4 0.0 0.09 12.1 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit UTP25 PF06862.12 ABK71608.1 - 0.053 12.3 0.0 4.9 5.8 0.0 2.2 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 LytR_C PF13399.6 ABK71608.1 - 0.1 13.6 0.3 0.55 11.3 0.1 2.4 2 1 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator Beta-lactamase PF00144.24 ABK71611.1 - 3.8e-59 200.6 5.5 4.9e-59 200.2 5.5 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 ABK71611.1 - 0.095 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase enzyme family TetR_C_31 PF17940.1 ABK71613.1 - 6.5e-17 61.7 0.3 1.3e-16 60.7 0.3 1.5 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK71613.1 - 2e-08 33.9 0.2 5.4e-08 32.5 0.1 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_40 PF14493.6 ABK71613.1 - 0.097 13.1 0.4 5.6 7.5 0.1 2.3 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_5 PF01022.20 ABK71613.1 - 0.12 12.3 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family KdpD PF02702.17 ABK71614.1 - 3.4e-89 297.8 0.1 6.9e-89 296.8 0.1 1.5 1 0 0 1 1 1 1 Osmosensitive K+ channel His kinase sensor domain DUF4118 PF13493.6 ABK71614.1 - 4.4e-19 68.3 10.7 8.1e-19 67.4 10.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4118) HATPase_c PF02518.26 ABK71614.1 - 1.1e-16 61.4 0.0 3.4e-16 59.7 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Usp PF00582.26 ABK71614.1 - 9.8e-11 42.3 1.3 8.7e-10 39.3 1.3 2.6 1 1 0 1 1 1 1 Universal stress protein family HisKA PF00512.25 ABK71614.1 - 0.0006 19.8 0.0 0.003 17.5 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain EMP70 PF02990.16 ABK71614.1 - 0.22 10.1 0.7 0.32 9.6 0.7 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 Tom6 PF17112.5 ABK71614.1 - 1.7 8.2 3.3 0.63 9.6 0.5 1.7 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom6, fungal E1-E2_ATPase PF00122.20 ABK71615.1 - 2.6e-34 118.3 3.2 2.6e-34 118.3 3.2 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 ABK71615.1 - 4.6e-32 112.0 3.1 7.9e-32 111.3 3.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ABK71615.1 - 0.00024 20.9 0.9 0.0012 18.7 0.7 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ABK71615.1 - 0.0019 18.6 0.1 0.012 16.0 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF5345 PF17280.2 ABK71615.1 - 0.1 12.6 0.1 0.33 10.9 0.1 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5345) DUF759 PF05537.11 ABK71615.1 - 0.11 11.4 0.0 0.27 10.1 0.0 1.6 2 0 0 2 2 2 0 Borrelia burgdorferi protein of unknown function (DUF759) NIBRIN_BRCT_II PF16508.5 ABK71615.1 - 0.11 12.8 0.1 0.48 10.8 0.1 2.0 1 1 1 2 2 2 0 Second BRCT domain on Nijmegen syndrome breakage protein Cadherin_4 PF17803.1 ABK71615.1 - 0.66 10.6 13.1 0.24 12.0 0.9 3.7 4 0 0 4 4 4 0 Bacterial cadherin-like domain MFS_1 PF07690.16 ABK71616.1 - 1.6e-30 106.2 46.3 1.1e-18 67.3 18.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK71616.1 - 2.3e-30 105.9 25.8 2.1e-23 82.9 5.9 2.0 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 ABK71616.1 - 1.6e-06 26.9 35.3 9e-06 24.5 8.1 3.0 1 1 2 3 3 3 3 MFS/sugar transport protein TRI12 PF06609.13 ABK71616.1 - 0.00022 19.8 6.3 0.00022 19.8 6.3 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) FMN_dh PF01070.18 ABK71617.1 - 1.1e-112 376.6 0.0 1.2e-112 376.4 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 ABK71617.1 - 0.00013 21.1 1.2 0.00017 20.7 0.7 1.3 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 ABK71617.1 - 0.0044 16.2 0.2 0.0068 15.6 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 ABK71617.1 - 0.011 15.0 0.1 0.18 11.1 0.3 2.1 1 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG NMO PF03060.15 ABK71617.1 - 0.011 15.1 0.9 0.018 14.4 0.9 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase His_biosynth PF00977.21 ABK71617.1 - 0.09 12.2 0.0 2.8 7.3 0.0 2.5 3 0 0 3 3 3 0 Histidine biosynthesis protein SSB PF00436.25 ABK71618.1 - 2.1e-31 108.0 0.0 2.6e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family tRNA_anti-codon PF01336.25 ABK71618.1 - 4.6e-06 26.5 0.1 8.6e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 ABK71618.1 - 0.012 15.8 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Trypsin_2 PF13365.6 ABK71619.1 - 1.1e-21 78.3 2.8 2.1e-21 77.4 2.8 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Colicin_V PF02674.16 ABK71619.1 - 9.9e-13 48.3 15.8 9.9e-13 48.3 15.8 1.8 2 0 0 2 2 2 1 Colicin V production protein Trypsin PF00089.26 ABK71619.1 - 2.2e-08 34.2 0.0 3.9e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Trypsin Peptidase_S46 PF10459.9 ABK71619.1 - 0.00015 20.6 0.5 0.026 13.2 0.4 2.1 1 1 1 2 2 2 2 Peptidase S46 PNTB PF02233.16 ABK71619.1 - 0.019 13.9 6.6 0.026 13.4 6.6 1.1 1 0 0 1 1 1 0 NAD(P) transhydrogenase beta subunit Peptidase_S7 PF00949.21 ABK71619.1 - 0.089 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S3 PF00944.19 ABK71619.1 - 0.098 12.5 0.3 0.23 11.2 0.3 1.6 1 0 0 1 1 1 0 Alphavirus core protein Anophelin PF10731.9 ABK71619.1 - 0.16 11.8 0.4 0.39 10.6 0.4 1.6 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito DUF3481 PF11980.8 ABK71619.1 - 1.4 8.6 5.3 1.1 9.1 0.8 2.4 2 0 0 2 2 2 0 C-terminal domain of neuropilin glycoprotein CPP1-like PF11833.8 ABK71619.1 - 5.3 6.6 12.9 2.8 7.6 4.7 2.4 1 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like AP_endonuc_2 PF01261.24 ABK71620.1 - 5.6e-22 78.2 0.0 8e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel MIT PF04212.18 ABK71620.1 - 0.0088 16.1 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DUF1218 PF06749.12 ABK71621.1 - 0.024 15.2 9.2 1.2 9.7 4.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) Trp_oprn_chp PF09534.10 ABK71621.1 - 0.031 14.1 16.9 0.013 15.3 9.4 2.0 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) MerC PF03203.14 ABK71621.1 - 0.16 12.4 11.1 0.29 11.6 11.1 1.4 1 1 0 1 1 1 0 MerC mercury resistance protein DUF2530 PF10745.9 ABK71621.1 - 1.4 9.3 18.9 2.4 8.5 5.7 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2530) Cyt_bd_oxida_II PF02322.15 ABK71621.1 - 2.1 7.7 15.4 0.048 13.0 6.7 1.8 1 1 1 2 2 2 0 Cytochrome bd terminal oxidase subunit II SLATT_1 PF18181.1 ABK71621.1 - 2.4 8.1 10.6 0.11 12.4 0.8 2.1 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Gram_pos_anchor PF00746.21 ABK71621.1 - 3.8 7.6 0.0 3.8 7.6 0.0 3.7 4 0 0 4 4 4 0 LPXTG cell wall anchor motif DUF4395 PF14340.6 ABK71621.1 - 4.4 7.6 17.0 1.3 9.4 3.8 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4395) DUF4131 PF13567.6 ABK71621.1 - 7.6 6.2 8.7 6.2 6.4 4.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Rax2 PF12768.7 ABK71621.1 - 9.6 5.6 9.2 11 5.3 8.2 1.5 1 1 0 1 1 1 0 Cortical protein marker for cell polarity Acyl-CoA_dh_1 PF00441.24 ABK71622.1 - 3.1e-37 128.1 0.8 5.1e-37 127.4 0.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK71622.1 - 7.2e-23 81.4 0.0 1.6e-22 80.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ABK71622.1 - 6.2e-22 77.6 0.0 1.4e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ABK71622.1 - 0.00051 20.3 0.5 0.001 19.4 0.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 ABK71622.1 - 0.13 12.8 0.0 0.34 11.5 0.0 1.8 1 1 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal FSH1 PF03959.13 ABK71623.1 - 2.7 7.6 3.7 21 4.7 0.6 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Bax1-I PF01027.20 ABK71623.1 - 7.3 6.4 19.6 0.056 13.3 3.5 2.8 1 1 1 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 adh_short_C2 PF13561.6 ABK71624.1 - 2.4e-67 226.9 2.4 2.8e-67 226.7 2.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK71624.1 - 3.6e-57 193.0 2.5 4.2e-57 192.8 2.5 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK71624.1 - 1e-12 48.4 0.8 1.4e-12 47.9 0.8 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 ABK71624.1 - 0.0069 15.8 0.0 0.014 14.8 0.0 1.5 1 1 1 2 2 2 1 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.18 ABK71624.1 - 0.028 14.3 0.8 0.057 13.3 0.6 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 ABK71624.1 - 0.13 11.7 0.4 1 8.7 0.4 2.2 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DFP PF04127.15 ABK71624.1 - 0.19 11.6 3.1 0.56 10.0 2.6 1.9 2 1 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein HupF_HypC PF01455.18 ABK71625.1 - 1.1e-25 89.6 0.4 1.3e-25 89.3 0.4 1.1 1 0 0 1 1 1 1 HupF/HypC family Leucyl-specific PF14795.6 ABK71625.1 - 0.023 14.8 0.0 0.055 13.5 0.0 1.6 2 0 0 2 2 2 0 Leucine-tRNA synthetase-specific domain Glyoxalase_4 PF13669.6 ABK71625.1 - 0.11 12.8 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ABC_tran PF00005.27 ABK71626.1 - 7.9e-26 91.2 0.0 1.2e-25 90.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK71626.1 - 2e-12 47.6 0.1 2.6e-07 30.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 ABK71626.1 - 0.00023 21.0 0.0 0.21 11.3 0.0 2.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 ABK71626.1 - 0.0007 20.2 0.0 0.001 19.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 ABK71626.1 - 0.0014 18.0 0.0 1.3 8.3 0.0 2.1 2 0 0 2 2 2 2 KaiC SRP54 PF00448.22 ABK71626.1 - 0.019 14.6 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain SbcCD_C PF13558.6 ABK71626.1 - 0.02 15.1 0.0 0.59 10.4 0.0 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 ABK71626.1 - 0.021 15.1 0.1 0.072 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 ABK71626.1 - 0.025 14.3 0.0 0.99 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 ABK71626.1 - 0.034 13.6 0.0 0.44 9.9 0.0 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 ABK71626.1 - 0.051 13.3 0.4 0.11 12.2 0.1 1.8 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.6 ABK71626.1 - 0.17 11.7 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ILVD_EDD PF00920.21 ABK71627.1 - 5.8e-154 513.5 6.4 6.5e-154 513.4 6.4 1.0 1 0 0 1 1 1 1 Dehydratase family Putative_PNPOx PF01243.20 ABK71628.1 - 1.3e-13 50.9 0.1 2.3e-09 37.3 0.0 2.9 2 1 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase Aldolase PF01081.19 ABK71629.1 - 5.8e-32 110.7 0.2 7.1e-32 110.4 0.2 1.0 1 0 0 1 1 1 1 KDPG and KHG aldolase TMP-TENI PF02581.17 ABK71629.1 - 0.026 13.9 0.2 0.067 12.5 0.0 1.7 2 0 0 2 2 2 0 Thiamine monophosphate synthase HMGL-like PF00682.19 ABK71629.1 - 0.027 14.0 0.0 0.036 13.6 0.0 1.3 1 1 0 1 1 1 0 HMGL-like DUF222 PF02720.17 ABK71630.1 - 1.9e-16 60.4 19.5 2.8e-16 59.9 19.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF222) HNH PF01844.23 ABK71630.1 - 0.0042 17.2 2.1 0.0082 16.3 2.1 1.4 1 0 0 1 1 1 1 HNH endonuclease HNH_5 PF14279.6 ABK71630.1 - 0.028 14.3 0.9 0.052 13.4 0.9 1.4 1 0 0 1 1 1 0 HNH endonuclease Lyase_1 PF00206.20 ABK71631.1 - 7.7e-21 74.8 0.0 1.1e-20 74.3 0.0 1.2 1 0 0 1 1 1 1 Lyase Fungal_trans_2 PF11951.8 ABK71631.1 - 0.17 10.7 0.2 2 7.1 0.0 2.0 2 0 0 2 2 2 0 Fungal specific transcription factor domain ABC_tran PF00005.27 ABK71632.1 - 1e-31 110.3 0.0 1.4e-31 109.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter OB_MalK PF17912.1 ABK71632.1 - 1e-08 35.9 0.0 4e-08 34.0 0.0 2.1 1 0 0 1 1 1 1 MalK OB fold domain AAA_21 PF13304.6 ABK71632.1 - 1.7e-08 34.6 0.0 0.0063 16.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system TOBE_2 PF08402.10 ABK71632.1 - 1.5e-07 31.5 0.8 4.3e-07 30.0 0.8 1.9 1 0 0 1 1 1 1 TOBE domain CysA_C_terminal PF17850.1 ABK71632.1 - 1e-06 29.2 0.9 1e-06 29.2 0.9 2.5 3 0 0 3 3 1 1 CysA C-terminal regulatory domain AAA_16 PF13191.6 ABK71632.1 - 2e-05 25.0 0.6 0.0027 18.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 ABK71632.1 - 0.00032 20.2 0.1 0.0021 17.5 0.1 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 ABK71632.1 - 0.0021 18.0 0.0 0.0041 17.1 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 ABK71632.1 - 0.0021 18.5 0.0 0.0058 17.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ABK71632.1 - 0.0022 18.2 0.5 0.0062 16.8 0.3 1.9 1 1 1 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ABK71632.1 - 0.0027 17.6 0.1 0.0055 16.6 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 ABK71632.1 - 0.005 16.6 2.4 0.0062 16.3 0.3 2.1 2 1 0 2 2 2 1 AAA domain TOBE PF03459.17 ABK71632.1 - 0.0067 16.7 3.5 0.014 15.7 1.2 2.8 2 1 0 2 2 1 1 TOBE domain AAA_25 PF13481.6 ABK71632.1 - 0.0086 15.7 0.0 0.12 11.9 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ABK71632.1 - 0.013 15.5 0.2 0.79 9.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 ABK71632.1 - 0.018 14.8 0.1 0.041 13.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 ABK71632.1 - 0.03 14.8 0.1 0.049 14.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ABK71632.1 - 0.033 13.5 0.0 0.078 12.3 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 ABK71632.1 - 0.057 13.6 1.0 0.13 12.4 1.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 ABK71632.1 - 0.35 10.5 0.0 0.5 10.0 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain ADH_N PF08240.12 ABK71633.1 - 7.4e-30 103.1 0.8 1.3e-29 102.3 0.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ABK71633.1 - 2.9e-18 66.1 0.1 5e-18 65.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ABK71633.1 - 1.3e-08 34.6 0.0 1.8e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 ABK71633.1 - 0.00041 21.4 0.0 0.00092 20.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 ABK71633.1 - 0.015 15.6 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 ABK71633.1 - 0.025 13.8 0.4 0.037 13.3 0.4 1.1 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 ABK71633.1 - 0.054 13.6 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1491 PF07372.12 ABK71633.1 - 0.18 12.2 0.0 0.32 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1491) ThiF PF00899.21 ABK71634.1 - 2.7e-25 89.1 0.1 4.8e-25 88.3 0.1 1.3 1 0 0 1 1 1 1 ThiF family Nitroreductase PF00881.24 ABK71634.1 - 2.5e-06 27.6 6.6 0.091 12.8 0.0 3.9 2 2 1 3 3 3 3 Nitroreductase family TM1586_NiRdase PF14512.6 ABK71634.1 - 0.11 12.1 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative TM nitroreductase adh_short_C2 PF13561.6 ABK71635.1 - 6.5e-50 169.9 0.2 7.8e-50 169.6 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK71635.1 - 2.1e-43 148.1 0.0 2.8e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK71635.1 - 2.2e-11 44.0 0.1 3e-11 43.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Beta-lactamase PF00144.24 ABK71637.1 - 4.5e-70 236.5 1.4 5.7e-70 236.2 1.4 1.0 1 0 0 1 1 1 1 Beta-lactamase OHCU_decarbox PF09349.10 ABK71638.1 - 9.1e-30 104.2 0.0 1e-29 104.0 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase Hydrolase_like PF13242.6 ABK71638.1 - 0.15 12.2 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Transp_cyt_pur PF02133.15 ABK71639.1 - 3.9e-46 157.7 47.3 4.5e-46 157.5 47.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin adh_short_C2 PF13561.6 ABK71640.1 - 7.8e-67 225.2 4.3 8.8e-67 225.1 4.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK71640.1 - 6.5e-49 166.1 2.2 8.1e-49 165.7 2.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK71640.1 - 7.5e-06 26.0 2.5 1.2e-05 25.3 2.5 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK71640.1 - 9.5e-05 22.0 2.7 0.00057 19.4 2.7 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.21 ABK71640.1 - 0.015 15.3 0.9 0.036 14.1 0.9 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Acyl-CoA_dh_1 PF00441.24 ABK71641.1 - 8.3e-22 78.0 0.0 1.4e-21 77.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK71641.1 - 8.8e-20 70.7 0.0 1.6e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ABK71641.1 - 1.9e-07 31.7 0.0 3.9e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain FA_desaturase PF00487.24 ABK71642.1 - 7.7e-29 101.3 2.8 1e-28 100.9 2.8 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Dehydratase_SU PF02287.15 ABK71644.1 - 1.9e-30 105.6 1.2 2.1e-30 105.5 1.2 1.0 1 0 0 1 1 1 1 Dehydratase small subunit PIG-L PF02585.17 ABK71645.1 - 3.9e-26 92.2 0.3 6.2e-26 91.6 0.3 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase SIS_2 PF13580.6 ABK71646.1 - 1.5e-14 54.2 0.3 2.1e-14 53.7 0.3 1.2 1 0 0 1 1 1 1 SIS domain SIS PF01380.22 ABK71646.1 - 3.5e-07 30.1 0.1 7.4e-07 29.1 0.0 1.6 2 0 0 2 2 2 1 SIS domain AA_permease_2 PF13520.6 ABK71647.1 - 1.1e-27 97.0 36.1 1.3e-27 96.7 36.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ABK71647.1 - 7.8e-17 61.0 37.1 1.5e-16 60.1 37.1 1.4 1 1 0 1 1 1 1 Amino acid permease NUDIX PF00293.28 ABK71648.1 - 1.9e-16 60.3 0.1 2.6e-16 59.9 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain DUF4859 PF16151.5 ABK71648.1 - 0.051 13.5 0.5 0.28 11.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4859) PaRep2a PF07903.11 ABK71648.1 - 0.065 13.1 0.0 0.065 13.1 0.0 1.6 2 0 0 2 2 2 0 PaRep2a protein Peptidase_S58 PF03576.14 ABK71649.1 - 3.9e-105 351.6 2.6 4.5e-105 351.5 2.6 1.0 1 0 0 1 1 1 1 Peptidase family S58 4HBT_3 PF13622.6 ABK71651.1 - 3.4e-22 79.9 1.0 4e-22 79.7 1.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily TetR_N PF00440.23 ABK71652.1 - 4.7e-29 99.9 4.0 7.5e-14 51.3 0.0 2.5 2 0 0 2 2 2 2 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 ABK71652.1 - 2.7e-08 34.1 1.2 0.00078 19.7 0.4 2.5 2 0 0 2 2 2 2 Tetracyclin repressor-like, C-terminal domain HTH_3 PF01381.22 ABK71652.1 - 0.00033 20.6 0.0 0.038 14.0 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix HTH_23 PF13384.6 ABK71652.1 - 0.0012 18.6 3.4 0.056 13.3 0.1 4.1 4 0 0 4 4 4 1 Homeodomain-like domain HTH_AsnC-type PF13404.6 ABK71652.1 - 0.0015 18.3 0.8 5.4 6.9 0.0 4.2 4 0 0 4 4 4 1 AsnC-type helix-turn-helix domain HTH_31 PF13560.6 ABK71652.1 - 0.0054 17.1 0.9 2.3 8.6 0.0 2.9 2 0 0 2 2 2 1 Helix-turn-helix domain DUF134 PF02001.16 ABK71652.1 - 0.0073 16.8 0.1 0.21 12.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function DUF134 HTH_Tnp_1_2 PF13022.6 ABK71652.1 - 0.012 15.7 0.0 2.8 8.1 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix of insertion element transposase HTH_24 PF13412.6 ABK71652.1 - 0.013 15.1 0.0 4.9 6.8 0.0 3.0 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding APH PF01636.23 ABK71652.1 - 0.019 14.9 3.0 0.043 13.7 3.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family DprA_WH PF17782.1 ABK71652.1 - 0.019 15.0 1.0 1.7 8.8 0.0 3.7 3 0 0 3 3 3 0 DprA winged helix domain HTH_AraC PF00165.23 ABK71652.1 - 0.038 14.1 0.0 1.3 9.2 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_19 PF12844.7 ABK71652.1 - 0.094 12.8 0.1 17 5.5 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 ABK71652.1 - 0.1 12.3 0.7 2.1 8.1 0.1 3.0 3 0 0 3 3 3 0 Sigma-70, region 4 HTH_26 PF13443.6 ABK71652.1 - 0.11 12.9 0.0 4.9 7.7 0.0 2.6 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain TetR_C_15 PF17918.1 ABK71652.1 - 0.52 11.1 15.2 0.14 12.9 1.2 3.2 4 1 0 4 4 2 0 Tetracyclin repressor-like, C-terminal domain OsmC PF02566.19 ABK71653.1 - 1.2e-09 38.5 0.0 1.6e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 OsmC-like protein His_Phos_1 PF00300.22 ABK71654.1 - 2.7e-49 167.5 2.1 3.6e-49 167.1 2.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) p450 PF00067.22 ABK71655.1 - 3.5e-41 141.4 0.0 2.1e-31 109.2 0.1 3.0 1 1 1 2 2 2 2 Cytochrome P450 Peripla_BP_3 PF13377.6 ABK71656.1 - 1e-31 110.5 0.7 1e-31 110.5 0.7 1.7 2 1 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 ABK71656.1 - 6.5e-30 104.5 0.0 8.5e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 ABK71656.1 - 2.3e-19 70.0 0.0 3e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain LacI PF00356.21 ABK71656.1 - 2e-06 27.5 0.1 3.4e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family HTH_29 PF13551.6 ABK71656.1 - 0.0033 17.4 0.8 0.16 12.0 0.1 3.2 3 1 1 4 4 4 1 Winged helix-turn helix HTH_IclR PF09339.10 ABK71656.1 - 0.025 14.4 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_23 PF13384.6 ABK71656.1 - 0.032 14.0 0.1 0.16 11.8 0.0 2.3 2 1 0 2 2 2 0 Homeodomain-like domain Sigma54_DBD PF04552.13 ABK71656.1 - 0.048 13.4 0.1 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 Sigma-54, DNA binding domain HTH_3 PF01381.22 ABK71656.1 - 0.17 12.0 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix Toprim_N PF08275.11 ABK71657.1 - 1e-36 125.8 0.0 1.5e-36 125.3 0.0 1.3 1 0 0 1 1 1 1 DNA primase catalytic core, N-terminal domain zf-CHC2 PF01807.20 ABK71657.1 - 1.8e-35 120.7 0.0 3.2e-35 119.9 0.0 1.4 1 0 0 1 1 1 1 CHC2 zinc finger DnaG_DnaB_bind PF08278.11 ABK71657.1 - 9.2e-32 110.3 0.1 3.4e-31 108.4 0.0 2.0 2 0 0 2 2 2 1 DNA primase DnaG DnaB-binding DnaB_bind PF10410.9 ABK71657.1 - 1.1e-21 76.7 0.3 3.7e-21 75.1 0.0 2.1 2 0 0 2 2 2 1 DnaB-helicase binding domain of primase Toprim_4 PF13662.6 ABK71657.1 - 3.3e-13 49.9 0.0 1e-12 48.4 0.0 1.8 1 0 0 1 1 1 1 Toprim domain Toprim_2 PF13155.6 ABK71657.1 - 2.1e-08 34.5 0.6 4.5e-08 33.4 0.1 1.9 2 0 0 2 2 2 1 Toprim-like Toprim PF01751.22 ABK71657.1 - 6.6e-07 29.5 0.0 2.1e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 Toprim domain Toprim_3 PF13362.6 ABK71657.1 - 0.00071 19.9 0.1 0.0022 18.3 0.1 1.9 1 0 0 1 1 1 1 Toprim domain DUF5549 PF17703.1 ABK71657.1 - 0.065 12.9 2.6 0.11 12.1 2.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5549) PfkB PF00294.24 ABK71658.1 - 7.9e-48 163.3 0.0 9.2e-48 163.1 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 ABK71658.1 - 8.9e-07 28.5 0.0 1.4e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase NAD_kinase PF01513.21 ABK71658.1 - 0.069 12.3 0.2 0.11 11.7 0.2 1.2 1 0 0 1 1 1 0 ATP-NAD kinase Bac_luciferase PF00296.20 ABK71659.1 - 5.3e-46 157.5 5.5 1.5e-45 156.0 5.5 1.7 1 1 0 1 1 1 1 Luciferase-like monooxygenase NIL PF09383.10 ABK71659.1 - 0.071 13.0 0.5 7.3 6.5 0.0 3.2 3 0 0 3 3 3 0 NIL domain DXP_synthase_N PF13292.6 ABK71660.1 - 1.6e-108 362.1 0.0 2.8e-108 361.3 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 ABK71660.1 - 1e-36 126.3 0.1 6.8e-36 123.6 0.0 2.3 2 1 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ABK71660.1 - 2.8e-27 95.1 0.6 1.2e-26 93.0 0.2 2.3 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 ABK71660.1 - 4e-07 30.3 0.0 1e-06 29.0 0.0 1.7 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II TPP_enzyme_C PF02775.21 ABK71660.1 - 1.1e-06 28.6 0.1 2.5e-05 24.1 0.0 3.1 4 0 0 4 4 4 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain NTP_transf_3 PF12804.7 ABK71660.1 - 0.00063 20.1 1.2 0.36 11.2 0.3 2.8 2 0 0 2 2 2 2 MobA-like NTP transferase domain E1_dh PF00676.20 ABK71660.1 - 0.006 15.6 0.0 0.029 13.3 0.0 1.9 2 0 0 2 2 2 1 Dehydrogenase E1 component Glyco_trans_4_4 PF13579.6 ABK71660.1 - 0.015 15.7 9.7 0.035 14.5 2.2 3.0 3 0 0 3 3 3 0 Glycosyl transferase 4-like domain Usp PF00582.26 ABK71660.1 - 0.084 13.4 1.8 2.7 8.5 0.0 3.5 2 1 1 3 3 3 0 Universal stress protein family Beta-Casp PF10996.8 ABK71660.1 - 0.098 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Beta-Casp domain SnoaL_2 PF12680.7 ABK71661.1 - 1.1e-10 42.1 3.6 1.3e-10 41.8 3.6 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 ABK71661.1 - 3e-06 27.6 0.3 4e-06 27.2 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 ABK71661.1 - 0.0011 19.3 0.2 0.0013 18.9 0.2 1.2 1 0 0 1 1 1 1 SnoaL-like domain LEH PF07858.12 ABK71661.1 - 0.0025 17.9 1.4 0.0031 17.6 1.4 1.1 1 0 0 1 1 1 1 Limonene-1,2-epoxide hydrolase catalytic domain Ada_Zn_binding PF02805.16 ABK71662.1 - 0.14 12.2 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 Metal binding domain of Ada ABC_tran PF00005.27 ABK71663.1 - 5.9e-33 114.3 0.0 7.8e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK71663.1 - 3.2e-10 40.3 0.1 2.5e-05 24.3 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ABK71663.1 - 3.8e-05 24.1 0.4 6.9e-05 23.3 0.4 1.4 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 ABK71663.1 - 0.00011 21.8 0.0 0.0018 17.7 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 ABK71663.1 - 0.00016 21.5 0.3 0.00041 20.1 0.3 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ABK71663.1 - 0.0007 19.9 1.6 0.011 16.0 1.6 2.2 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 ABK71663.1 - 0.00081 19.0 1.3 0.0055 16.3 0.9 2.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ABK71663.1 - 0.0011 19.2 0.6 0.012 15.7 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 ABK71663.1 - 0.0014 19.0 0.1 0.0025 18.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ABK71663.1 - 0.0021 17.8 0.0 0.0042 16.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 ABK71663.1 - 0.0032 18.0 0.0 0.0053 17.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF3584 PF12128.8 ABK71663.1 - 0.0036 14.9 0.0 0.0047 14.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) cobW PF02492.19 ABK71663.1 - 0.0043 16.7 0.1 0.01 15.5 0.0 1.7 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 ABK71663.1 - 0.0044 17.0 0.2 0.026 14.4 0.0 2.2 2 1 1 3 3 3 1 NACHT domain AAA PF00004.29 ABK71663.1 - 0.0067 16.9 0.0 0.025 15.0 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 ABK71663.1 - 0.017 15.1 0.0 0.068 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 ABK71663.1 - 0.017 14.7 0.2 0.04 13.6 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 ABK71663.1 - 0.021 14.0 0.0 0.042 13.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain MMR_HSR1 PF01926.23 ABK71663.1 - 0.03 14.4 0.3 0.078 13.1 0.1 2.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase TsaE PF02367.17 ABK71663.1 - 0.037 14.0 0.0 0.099 12.6 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 ABK71663.1 - 0.038 13.3 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.15 ABK71663.1 - 0.041 13.8 0.0 1 9.3 0.0 2.3 2 0 0 2 2 2 0 NTPase Septin PF00735.18 ABK71663.1 - 0.042 13.1 0.0 0.062 12.6 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_27 PF13514.6 ABK71663.1 - 0.047 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ABK71663.1 - 0.047 13.4 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 ABK71663.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 ABK71663.1 - 0.055 13.7 0.6 0.2 11.9 0.4 2.3 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 ABK71663.1 - 0.058 13.1 0.0 0.33 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain SbcCD_C PF13558.6 ABK71663.1 - 0.13 12.5 0.1 2 8.7 0.0 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 ABK71663.1 - 0.16 12.5 0.0 0.39 11.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 ABK71663.1 - 0.18 11.7 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Thiolase_N PF00108.23 ABK71664.1 - 2.3e-98 328.7 2.2 2.3e-98 328.7 2.2 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ABK71664.1 - 5.9e-45 151.9 2.0 1.4e-44 150.7 2.0 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 ABK71664.1 - 0.0031 17.3 2.5 0.28 11.1 0.0 2.9 3 0 0 3 3 3 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 ABK71664.1 - 0.0071 15.9 0.2 0.0071 15.9 0.2 2.9 4 1 0 4 4 4 1 Beta-ketoacyl synthase, N-terminal domain DbpA PF03880.15 ABK71664.1 - 0.055 13.5 0.1 0.58 10.2 0.1 2.2 2 0 0 2 2 2 0 DbpA RNA binding domain Jag_N PF14804.6 ABK71664.1 - 0.3 11.5 2.2 9.4 6.7 0.0 2.9 3 0 0 3 3 3 0 Jag N-terminus FAD_binding_5 PF00941.21 ABK71665.1 - 4e-44 150.4 0.0 6.7e-44 149.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 ABK71665.1 - 2.5e-19 69.3 0.8 4.9e-19 68.4 0.1 1.8 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Rick_17kDa_Anti PF05433.15 ABK71665.1 - 0.94 9.4 5.4 2.7 7.9 0.4 2.6 2 0 0 2 2 2 0 Glycine zipper 2TM domain Bac_luciferase PF00296.20 ABK71667.1 - 1e-58 199.3 3.6 1.4e-58 198.8 3.2 1.4 1 1 1 2 2 2 2 Luciferase-like monooxygenase Sugar_tr PF00083.24 ABK71668.1 - 7.6e-47 160.2 20.5 1.1e-46 159.7 20.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ABK71668.1 - 2.1e-42 145.4 63.5 3.1e-33 115.2 33.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 ABK71668.1 - 7.5e-06 24.6 19.4 0.00016 20.3 3.0 2.5 2 1 0 2 2 2 2 Transmembrane secretion effector OATP PF03137.20 ABK71668.1 - 0.00013 20.4 8.0 0.00029 19.3 1.5 2.3 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 ABK71668.1 - 0.00019 20.1 3.9 0.00019 20.1 3.9 3.2 3 1 1 4 4 4 1 MFS/sugar transport protein MFS_1_like PF12832.7 ABK71668.1 - 0.00023 20.2 22.4 0.00092 18.2 5.2 2.3 2 0 0 2 2 2 2 MFS_1 like family TRI12 PF06609.13 ABK71668.1 - 0.00092 17.7 13.7 0.012 14.1 0.2 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF4131 PF13567.6 ABK71668.1 - 8.5 6.0 20.6 0.65 9.6 0.1 4.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) Radical_SAM PF04055.21 ABK71669.1 - 1.7e-29 103.4 0.0 1.3e-14 54.9 0.0 2.9 3 0 0 3 3 3 2 Radical SAM superfamily Methyltransf_23 PF13489.6 ABK71670.1 - 9.3e-09 35.3 0.0 1.2e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain DJ-1_PfpI PF01965.24 ABK71671.1 - 6.4e-24 84.6 0.0 1.2e-23 83.8 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family HTH_18 PF12833.7 ABK71671.1 - 4.9e-22 78.0 0.8 9.8e-22 77.0 0.8 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 ABK71671.1 - 1.9e-11 43.7 0.0 0.00026 21.0 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family GATase PF00117.28 ABK71671.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Acyl-CoA_dh_M PF02770.19 ABK71672.1 - 6.4e-22 77.6 0.0 1.2e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ABK71672.1 - 2.2e-10 41.2 0.0 4.5e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 ABK71672.1 - 2.8e-05 24.4 0.2 0.0001 22.5 0.0 2.0 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 ABK71672.1 - 0.0053 16.5 0.0 0.0088 15.7 0.0 1.3 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal WXG100 PF06013.12 ABK71673.1 - 0.00065 19.9 5.1 0.00077 19.6 5.1 1.1 1 0 0 1 1 1 1 Proteins of 100 residues with WXG Sigma70_r4_2 PF08281.12 ABK71674.1 - 9.6e-16 57.2 0.3 2e-15 56.2 0.3 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 ABK71674.1 - 1.7e-15 56.5 4.2 2.9e-15 55.8 3.7 1.7 1 1 0 1 1 1 1 Sigma-70 region 2 Sigma70_ECF PF07638.11 ABK71674.1 - 2.4e-08 34.1 2.0 7.8e-08 32.4 2.0 1.7 1 1 0 1 1 1 1 ECF sigma factor Sigma70_r4 PF04545.16 ABK71674.1 - 1.6e-07 30.7 0.1 3.5e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_28 PF13518.6 ABK71674.1 - 0.00068 19.7 0.3 0.0036 17.4 0.2 2.2 1 1 1 2 2 2 1 Helix-turn-helix domain DUF134 PF02001.16 ABK71674.1 - 0.0014 19.2 0.0 0.0022 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF134 HTH_23 PF13384.6 ABK71674.1 - 0.013 15.2 0.2 0.036 13.9 0.2 1.8 1 0 0 1 1 1 0 Homeodomain-like domain GerE PF00196.19 ABK71674.1 - 0.016 14.7 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Terminase_5 PF06056.12 ABK71674.1 - 0.021 14.7 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_38 PF13936.6 ABK71674.1 - 0.022 14.5 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain acVLRF1 PF18859.1 ABK71674.1 - 0.068 13.5 0.8 0.068 13.5 0.8 2.0 2 1 0 2 2 2 0 Actinobacteria/chloroflexi VLRF1 release factor Acyl-CoA_dh_M PF02770.19 ABK71675.1 - 2.7e-24 85.2 0.2 5.4e-24 84.2 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ABK71675.1 - 4.2e-24 85.4 0.1 4.2e-24 85.4 0.1 2.0 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 ABK71675.1 - 3.2e-23 82.6 0.5 6.7e-23 81.6 0.5 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 ABK71675.1 - 1.4e-05 25.4 0.5 1.4e-05 25.4 0.5 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DDE_Tnp_ISL3 PF01610.17 ABK71677.1 - 1.6e-64 217.9 0.0 2.1e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Transposase zf-ISL3 PF14690.6 ABK71677.1 - 1.1e-09 38.8 4.6 1.8e-09 38.1 2.5 2.5 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HTH_Tnp_ISL3 PF13542.6 ABK71677.1 - 2.4e-08 33.2 1.6 7e-08 31.8 1.6 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 FA_desaturase_2 PF03405.14 ABK71679.1 - 4.2e-88 295.3 0.1 5e-88 295.1 0.1 1.0 1 0 0 1 1 1 1 Fatty acid desaturase LCM PF04072.14 ABK71680.1 - 2.4e-62 210.3 0.3 3.1e-62 209.9 0.3 1.1 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase DUF2065 PF09838.9 ABK71680.1 - 0.014 15.4 0.1 0.041 13.9 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2065) PhoU PF01895.19 ABK71681.1 - 8.4e-26 90.3 4.1 4e-12 46.4 0.5 2.1 2 0 0 2 2 2 2 PhoU domain PhoU_div PF01865.16 ABK71681.1 - 0.012 14.9 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF47 adh_short PF00106.25 ABK71682.1 - 8.3e-50 169.0 6.4 1.1e-49 168.6 6.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK71682.1 - 1.6e-37 129.3 7.4 2e-37 129.0 7.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK71682.1 - 1.5e-07 31.5 6.5 2.2e-07 31.0 6.5 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK71682.1 - 1.8e-05 24.3 1.4 3e-05 23.6 1.4 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ABK71682.1 - 0.021 13.9 0.3 0.03 13.3 0.3 1.3 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family CbiA PF01656.23 ABK71682.1 - 0.064 13.3 0.0 0.086 12.9 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AdoHcyase_NAD PF00670.21 ABK71682.1 - 0.096 12.7 3.3 0.16 12.1 3.3 1.6 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.18 ABK71682.1 - 0.17 11.7 1.0 0.28 11.0 1.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAGK_cat PF00781.24 ABK71683.1 - 8.9e-20 70.6 0.2 1.5e-19 69.8 0.2 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain PAP2 PF01569.21 ABK71683.1 - 1.3e-18 67.1 1.1 2.7e-18 66.1 1.1 1.4 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 ABK71683.1 - 2.2e-06 27.5 0.7 4.4e-06 26.5 0.7 1.4 1 0 0 1 1 1 1 PAP2 superfamily NAD_kinase PF01513.21 ABK71683.1 - 8.4e-05 21.9 0.1 0.00012 21.4 0.1 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Pkinase PF00069.25 ABK71684.1 - 1.1e-43 149.5 0.0 1.4e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ABK71684.1 - 1.1e-24 87.1 0.0 1.5e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ABK71684.1 - 1.1e-06 28.7 8.2 1.7e-05 24.9 0.7 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 ABK71684.1 - 0.00077 18.9 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ABK71684.1 - 0.18 10.5 0.0 0.32 9.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase BPD_transp_1 PF00528.22 ABK71685.1 - 3.5e-22 79.1 14.9 5.3e-22 78.4 14.9 1.4 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Maf PF02545.14 ABK71686.1 - 1.3e-40 138.9 0.0 1.5e-40 138.8 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein MucBP_2 PF17965.1 ABK71687.1 - 0.048 14.2 0.1 0.078 13.6 0.1 1.4 1 1 0 1 1 1 0 Mucin binding domain TraT PF05818.12 ABK71687.1 - 0.36 10.5 5.6 1.4 8.6 0.0 2.5 1 1 1 2 2 2 0 Enterobacterial TraT complement resistance protein PadR PF03551.14 ABK71688.1 - 2.2e-09 37.1 0.0 4.1e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_34 PF13601.6 ABK71688.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_27 PF13463.6 ABK71688.1 - 0.11 13.1 0.1 0.23 12.0 0.1 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain Cdc6_C PF09079.11 ABK71688.1 - 0.15 12.0 0.1 0.35 10.9 0.1 1.5 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain Response_reg PF00072.24 ABK71689.1 - 2.2e-20 72.9 0.0 3.2e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain HTH_23 PF13384.6 ABK71689.1 - 3.3e-05 23.6 0.1 0.00011 21.8 0.1 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_11 PF08279.12 ABK71689.1 - 4.7e-05 23.2 0.0 9.2e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 HTH domain TrmB PF01978.19 ABK71689.1 - 5.9e-05 22.9 0.2 0.00017 21.4 0.1 1.8 2 0 0 2 2 1 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 ABK71689.1 - 0.00032 20.2 0.0 0.00062 19.3 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 ABK71689.1 - 0.0011 18.7 0.2 0.0033 17.2 0.0 2.0 2 0 0 2 2 1 1 IclR helix-turn-helix domain HTH_29 PF13551.6 ABK71689.1 - 0.0012 18.8 0.4 0.0037 17.2 0.4 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_10 PF04967.12 ABK71689.1 - 0.0018 18.0 0.1 0.011 15.5 0.0 2.3 2 0 0 2 2 2 1 HTH DNA binding domain HTH_Crp_2 PF13545.6 ABK71689.1 - 0.0034 17.3 0.1 0.016 15.2 0.0 2.0 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_7 PF02796.15 ABK71689.1 - 0.0091 16.1 0.0 0.024 14.7 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase Cation_ATPase_N PF00690.26 ABK71689.1 - 0.022 14.4 0.6 0.062 13.0 0.0 2.0 3 0 0 3 3 2 0 Cation transporter/ATPase, N-terminus HTH_17 PF12728.7 ABK71689.1 - 0.026 14.7 0.1 0.074 13.3 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_20 PF12840.7 ABK71689.1 - 0.027 14.5 0.3 2.4 8.3 0.1 3.2 1 1 2 3 3 3 0 Helix-turn-helix domain MarR_2 PF12802.7 ABK71689.1 - 0.029 14.2 0.1 0.077 12.9 0.1 1.8 1 0 0 1 1 1 0 MarR family HTH_3 PF01381.22 ABK71689.1 - 0.03 14.4 0.0 0.07 13.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix SelB-wing_3 PF09107.11 ABK71689.1 - 0.057 13.1 0.4 9.9 5.9 0.1 2.4 2 0 0 2 2 2 0 Elongation factor SelB, winged helix Sigma70_r4_2 PF08281.12 ABK71689.1 - 0.059 13.1 1.0 0.14 11.8 0.0 2.1 3 0 0 3 3 1 0 Sigma-70, region 4 TetR_N PF00440.23 ABK71689.1 - 0.066 13.0 0.1 1.1 9.1 0.0 2.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family FaeA PF04703.12 ABK71689.1 - 0.093 13.1 0.3 0.85 10.0 0.0 2.3 2 0 0 2 2 2 0 FaeA-like protein LZ_Tnp_IS481 PF13011.6 ABK71689.1 - 0.097 13.2 2.6 0.52 10.9 0.3 2.7 2 1 1 3 3 3 0 leucine-zipper of insertion element IS481 HTH_AsnC-type PF13404.6 ABK71689.1 - 0.11 12.4 1.4 0.28 11.0 0.2 2.4 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_22 PF13309.6 ABK71689.1 - 0.11 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 HTH domain HTH_Tnp_1_2 PF13022.6 ABK71689.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_micro PF17007.5 ABK71689.1 - 0.14 11.0 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 HTH-like TnsD PF15978.5 ABK71689.1 - 0.18 10.8 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Tn7-like transposition protein D HTH_31 PF13560.6 ABK71689.1 - 0.24 11.8 9.0 1.3 9.4 9.0 2.4 1 1 0 1 1 1 0 Helix-turn-helix domain IPPT PF01715.17 ABK71690.1 - 1.1e-67 228.2 0.0 1.3e-67 227.9 0.0 1.0 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 ABK71690.1 - 5.8e-06 25.9 0.0 9.2e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Isopentenyl transferase AAA_33 PF13671.6 ABK71690.1 - 2.8e-05 24.3 0.1 0.00055 20.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ABK71690.1 - 0.0038 17.6 0.5 0.0082 16.5 0.3 1.9 1 1 0 2 2 2 1 AAA ATPase domain Cytidylate_kin PF02224.18 ABK71690.1 - 0.0051 16.6 0.0 0.008 15.9 0.0 1.4 1 0 0 1 1 1 1 Cytidylate kinase AAA_22 PF13401.6 ABK71690.1 - 0.0088 16.3 0.0 0.02 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 ABK71690.1 - 0.018 15.5 0.0 0.029 14.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ABK71690.1 - 0.025 14.5 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 ABK71690.1 - 0.03 14.6 0.7 0.14 12.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 ABK71690.1 - 0.088 12.5 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.16 ABK71690.1 - 0.12 11.8 0.7 0.3 10.5 0.7 1.7 1 1 0 1 1 1 0 PhoH-like protein AAA_7 PF12775.7 ABK71690.1 - 0.21 11.1 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 ABK71690.1 - 0.26 11.2 0.0 0.35 10.7 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ApbA_C PF08546.11 ABK71691.1 - 3.4e-27 95.1 0.0 5.6e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 ABK71691.1 - 2.1e-23 82.6 0.4 3.1e-23 82.1 0.4 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 ABK71691.1 - 4.2e-08 33.0 0.0 7.8e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_8 PF13450.6 ABK71691.1 - 1.6e-05 25.0 1.4 4.2e-05 23.7 1.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ABK71691.1 - 2e-05 24.3 0.7 4.3e-05 23.3 0.7 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ABK71691.1 - 4.8e-05 22.7 0.8 6.6e-05 22.3 0.2 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ABK71691.1 - 0.00058 19.2 1.3 0.0011 18.3 0.2 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 ABK71691.1 - 0.00079 18.8 0.2 0.0014 17.9 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain ThiF PF00899.21 ABK71691.1 - 0.00084 18.8 0.3 0.0014 18.1 0.3 1.3 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.6 ABK71691.1 - 0.0009 19.7 0.0 0.0022 18.4 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding 3HCDH_N PF02737.18 ABK71691.1 - 0.00092 19.1 1.0 0.0012 18.8 0.2 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 ABK71691.1 - 0.0014 18.7 0.0 0.0033 17.5 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 ABK71691.1 - 0.0018 18.8 0.0 0.0048 17.5 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.27 ABK71691.1 - 0.0018 18.8 0.3 0.0045 17.5 0.3 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 ABK71691.1 - 0.002 18.4 0.2 0.0051 17.0 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 ABK71691.1 - 0.0025 18.1 0.0 0.0049 17.1 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain B12-binding PF02310.19 ABK71691.1 - 0.0069 16.4 0.3 2.2 8.3 0.1 2.4 2 0 0 2 2 2 1 B12 binding domain HI0933_like PF03486.14 ABK71691.1 - 0.0071 15.1 0.6 0.01 14.6 0.6 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_2 PF03446.15 ABK71691.1 - 0.0075 16.4 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 ABK71691.1 - 0.034 13.5 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ABC_tran PF00005.27 ABK71692.1 - 1.7e-18 67.4 0.0 8.4e-18 65.2 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK71692.1 - 0.00058 19.8 1.3 0.0019 18.1 0.2 2.1 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ABK71692.1 - 0.0075 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ABK71692.1 - 0.008 16.2 0.1 0.018 15.1 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_23 PF13476.6 ABK71692.1 - 0.024 15.2 0.0 0.048 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 ABK71692.1 - 0.024 14.5 0.1 0.044 13.7 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase DUF3584 PF12128.8 ABK71692.1 - 0.026 12.1 0.1 0.036 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_16 PF13191.6 ABK71692.1 - 0.028 14.8 0.1 0.042 14.2 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain MeaB PF03308.16 ABK71692.1 - 0.072 12.1 0.2 0.27 10.2 0.1 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_15 PF13175.6 ABK71692.1 - 0.12 12.1 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Cpn60_TCP1 PF00118.24 ABK71693.1 - 4.3e-96 322.5 13.8 5.7e-96 322.1 13.8 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3383 PF11863.8 ABK71693.1 - 0.036 13.1 0.4 4.2 6.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3383) Beta-lactamase PF00144.24 ABK71694.1 - 8.6e-33 114.0 4.0 4e-32 111.8 4.0 1.8 1 1 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 ABK71694.1 - 0.013 15.1 0.0 0.23 11.0 0.0 2.1 2 0 0 2 2 2 0 Beta-lactamase enzyme family TetR_C_11 PF16859.5 ABK71695.1 - 1.7e-30 105.6 8.4 3e-30 104.8 8.4 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK71695.1 - 4.3e-12 45.6 1.3 4.6e-12 45.5 0.1 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_7 PF14246.6 ABK71695.1 - 8.9e-06 25.7 0.5 2e-05 24.6 0.5 1.6 1 1 0 1 1 1 1 AefR-like transcriptional repressor, C-terminal domain TetR_C_20 PF17925.1 ABK71695.1 - 0.11 12.8 6.1 2 8.8 1.0 3.5 3 1 1 4 4 4 0 Tetracyclin repressor-like, C-terminal domain DUF1330 PF07045.11 ABK71696.1 - 1.3e-28 99.1 0.1 1.4e-28 99.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1330) SIS PF01380.22 ABK71697.1 - 4e-58 194.9 0.2 1.2e-34 119.0 0.1 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 ABK71697.1 - 6.8e-21 74.9 0.1 1.7e-20 73.6 0.1 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 ABK71697.1 - 2.9e-15 56.3 0.0 5.6e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain SIS_2 PF13580.6 ABK71697.1 - 0.0033 17.5 0.1 0.012 15.6 0.0 2.0 1 1 0 1 1 1 1 SIS domain GATase_4 PF13230.6 ABK71697.1 - 0.0033 16.4 0.0 0.012 14.6 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferases class-II DUF2470 PF10615.9 ABK71698.1 - 1.3e-07 32.1 0.0 3e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Epimerase PF01370.21 ABK71699.1 - 8.5e-27 94.2 0.0 1.3e-26 93.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ABK71699.1 - 5e-18 65.6 0.0 8.2e-18 64.9 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 ABK71699.1 - 1.2e-16 61.1 0.1 2e-16 60.4 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ABK71699.1 - 2.5e-15 56.3 0.0 3.5e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ABK71699.1 - 5.7e-10 38.8 0.0 1.4e-07 30.9 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein NmrA PF05368.13 ABK71699.1 - 2.8e-05 23.8 0.2 4.8e-05 23.0 0.2 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 ABK71699.1 - 0.00037 19.7 0.2 0.0019 17.4 0.0 2.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 ABK71699.1 - 0.0024 17.8 0.2 0.17 11.8 0.2 2.3 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 ABK71699.1 - 0.0032 17.7 0.2 0.006 16.8 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 ABK71699.1 - 0.014 14.5 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.25 ABK71699.1 - 0.088 12.2 0.0 0.36 10.2 0.1 1.9 2 0 0 2 2 2 0 short chain dehydrogenase F420_oxidored PF03807.17 ABK71699.1 - 0.13 12.9 0.0 0.4 11.3 0.0 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Glyoxalase PF00903.25 ABK71700.1 - 8.8e-10 38.9 0.0 1.2e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ABK71700.1 - 1.1e-06 29.4 0.7 1.8e-06 28.7 0.7 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 ABK71700.1 - 2.3e-05 24.6 0.0 3.9e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Peptidase_Mx PF15887.5 ABK71701.1 - 6.4e-101 336.7 0.1 7.8e-101 336.4 0.1 1.1 1 0 0 1 1 1 1 Putative zinc-binding metallo-peptidase zinc-ribbon_6 PF10005.9 ABK71701.1 - 1.2e-26 93.2 1.8 1.9e-26 92.6 1.8 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 ABK71701.1 - 0.00013 21.2 4.4 0.0019 17.5 0.7 2.3 2 0 0 2 2 2 2 zinc-ribbon domain Peptidase_Mx1 PF15890.5 ABK71701.1 - 0.016 14.6 0.1 0.023 14.1 0.1 1.2 1 0 0 1 1 1 0 Putative zinc-binding metallo-peptidase DZR PF12773.7 ABK71701.1 - 0.17 12.0 6.0 0.93 9.6 6.0 1.9 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 ABK71701.1 - 0.77 9.6 4.0 0.65 9.8 1.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DUF1610 PF07754.11 ABK71701.1 - 4 7.5 7.5 0.46 10.5 0.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) TF_Zn_Ribbon PF08271.12 ABK71701.1 - 8.7 6.0 8.1 0.85 9.2 1.7 2.3 2 1 0 2 2 2 0 TFIIB zinc-binding UreD PF01774.17 ABK71702.1 - 1.3e-18 67.7 0.2 1.6e-18 67.5 0.2 1.1 1 0 0 1 1 1 1 UreD urease accessory protein TetR_N PF00440.23 ABK71704.1 - 6e-15 54.8 2.0 1.5e-14 53.5 2.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_7 PF14246.6 ABK71704.1 - 0.00013 22.0 0.9 0.00084 19.4 0.1 2.4 1 1 1 3 3 3 1 AefR-like transcriptional repressor, C-terminal domain TetR_C_24 PF17932.1 ABK71704.1 - 0.0084 16.4 0.2 0.031 14.5 0.1 1.9 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain SIR2_2 PF13289.6 ABK71704.1 - 0.13 12.4 0.0 2.3 8.3 0.0 2.2 1 1 1 2 2 2 0 SIR2-like domain TetR_C_15 PF17918.1 ABK71704.1 - 1.1 10.1 7.3 0.33 11.7 1.2 2.8 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain AAA_26 PF13500.6 ABK71705.1 - 9e-29 100.7 0.0 1.1e-28 100.4 0.0 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 ABK71705.1 - 1.3e-05 25.3 0.4 1.4e-05 25.1 0.4 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1611 PF07755.11 ABK71705.1 - 0.021 14.1 1.6 0.021 14.1 1.6 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1611_C) P-loop domain LPG_synthase_TM PF03706.13 ABK71706.1 - 3.6e-33 115.4 40.0 4.5e-33 115.1 40.0 1.1 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region CCSMST1 PF15013.6 ABK71706.1 - 0.046 13.9 0.2 0.15 12.2 0.1 1.9 2 0 0 2 2 2 0 CCSMST1 family DUF4231 PF14015.6 ABK71706.1 - 2.7 8.5 13.6 0.065 13.7 5.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DDE_Tnp_ISL3 PF01610.17 ABK71708.1 - 1.6e-64 217.9 0.0 2.1e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Transposase zf-ISL3 PF14690.6 ABK71708.1 - 1.1e-09 38.8 4.6 1.8e-09 38.1 2.5 2.5 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HTH_Tnp_ISL3 PF13542.6 ABK71708.1 - 2.4e-08 33.2 1.6 7e-08 31.8 1.6 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 DUF732 PF05305.14 ABK71709.1 - 1.9e-16 60.2 0.4 2.4e-16 59.9 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF732) BPD_transp_2 PF02653.16 ABK71710.1 - 1.1e-41 142.8 37.4 1.6e-41 142.2 37.4 1.2 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component DUF5453 PF17534.2 ABK71710.1 - 2.7 7.9 8.5 4.6 7.2 0.3 3.1 2 1 0 2 2 2 0 Family of unknown function (DUF5453) DUF543 PF04418.12 ABK71710.1 - 2.7 8.0 0.0 2.7 8.0 0.0 3.8 5 0 0 5 5 5 0 Domain of unknown function (DUF543) CPSase_L_D2 PF02786.17 ABK71711.1 - 2.2e-102 341.0 0.0 1.7e-65 220.5 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 ABK71711.1 - 2.5e-35 121.5 0.0 5.3e-35 120.4 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain MGS PF02142.22 ABK71711.1 - 4.8e-23 81.2 0.0 3e-22 78.6 0.0 2.5 2 0 0 2 2 2 1 MGS-like domain ATP-grasp PF02222.22 ABK71711.1 - 7.2e-13 48.5 0.0 2.2e-07 30.6 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 ABK71711.1 - 1.5e-11 44.2 0.0 0.0001 21.9 0.0 2.3 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 ABK71711.1 - 7.4e-09 35.4 0.0 7.5e-05 22.5 0.0 2.7 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 ABK71711.1 - 8.2e-07 29.2 0.0 0.00028 21.0 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_2 PF08442.10 ABK71711.1 - 0.00016 21.3 0.0 0.23 11.0 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_5 PF13549.6 ABK71711.1 - 0.0012 18.4 0.0 0.17 11.3 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_4 PF13535.6 ABK71711.1 - 0.0014 18.2 0.0 0.025 14.2 0.0 2.8 2 1 0 2 2 2 1 ATP-grasp domain AAA_2 PF07724.14 ABK71712.1 - 3.3e-50 170.5 0.0 5.6e-50 169.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) zf-C4_ClpX PF06689.13 ABK71712.1 - 9.3e-21 73.4 6.0 1.9e-20 72.4 6.0 1.6 1 0 0 1 1 1 1 ClpX C4-type zinc finger AAA PF00004.29 ABK71712.1 - 1.3e-17 64.5 0.1 5.1e-17 62.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 ABK71712.1 - 6.9e-17 61.3 0.1 1.9e-16 59.9 0.1 1.8 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 ABK71712.1 - 1.7e-07 31.3 0.0 3.1e-06 27.2 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 ABK71712.1 - 1.3e-05 24.7 0.1 0.0025 17.2 0.0 3.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 ABK71712.1 - 1.9e-05 24.5 0.2 0.00012 21.9 0.2 2.4 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ABK71712.1 - 7.1e-05 23.1 0.3 0.00066 20.0 0.1 2.5 2 1 0 2 2 1 1 AAA domain MCM PF00493.23 ABK71712.1 - 0.00028 20.1 0.0 0.0005 19.2 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain Sigma54_activat PF00158.26 ABK71712.1 - 0.00055 19.7 0.0 0.041 13.6 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 ABK71712.1 - 0.00057 19.9 0.1 0.0015 18.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 ABK71712.1 - 0.0013 18.6 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 ABK71712.1 - 0.004 17.7 0.0 0.0085 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain B12-binding_2 PF02607.17 ABK71712.1 - 0.0054 17.1 1.6 0.011 16.1 0.0 2.4 3 0 0 3 3 1 1 B12 binding domain Rad17 PF03215.15 ABK71712.1 - 0.0097 15.8 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_7 PF12775.7 ABK71712.1 - 0.013 15.0 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 ABK71712.1 - 0.014 15.7 0.0 0.03 14.7 0.0 1.7 1 1 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 ABK71712.1 - 0.019 15.1 0.0 0.046 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 ABK71712.1 - 0.021 14.3 0.0 0.044 13.2 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activ_2 PF14532.6 ABK71712.1 - 0.023 14.8 0.0 0.056 13.6 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.6 ABK71712.1 - 0.025 15.0 0.1 0.2 12.0 0.0 2.1 1 1 1 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 ABK71712.1 - 0.027 13.5 0.0 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein PduV-EutP PF10662.9 ABK71712.1 - 0.028 14.2 0.0 0.069 12.9 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 ABK71712.1 - 0.031 14.2 0.0 0.079 12.9 0.0 1.7 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 ABK71712.1 - 0.032 14.2 0.0 0.064 13.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 ABK71712.1 - 0.05 13.3 0.0 0.091 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ABK71712.1 - 0.054 14.0 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter TIP49 PF06068.13 ABK71712.1 - 0.06 12.5 0.1 0.14 11.3 0.1 1.6 1 1 0 1 1 1 0 TIP49 P-loop domain Viral_helicase1 PF01443.18 ABK71712.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Parvo_NS1 PF01057.17 ABK71712.1 - 0.21 10.6 0.0 0.34 10.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF4177 PF13783.6 ABK71713.1 - 2e-06 28.0 0.0 3.1e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4177) Abhydrolase_6 PF12697.7 ABK71714.1 - 0.0046 17.6 0.1 0.0049 17.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family ABC_tran PF00005.27 ABK71715.1 - 3.4e-21 76.2 0.0 4.3e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK71715.1 - 2.4e-05 24.3 0.0 0.024 14.5 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK71715.1 - 4e-05 23.2 0.1 0.0099 15.3 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ABK71715.1 - 0.00056 19.6 0.1 0.0012 18.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 ABK71715.1 - 0.0044 17.4 0.1 0.038 14.4 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 ABK71715.1 - 0.0054 16.3 0.3 0.034 13.7 0.1 2.3 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ABK71715.1 - 0.07 13.0 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 ABK71715.1 - 0.094 12.9 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 ABK71715.1 - 0.1 11.2 0.0 0.7 8.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 ABK71715.1 - 0.17 12.4 0.1 0.27 11.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain BT1 PF03092.16 ABK71717.1 - 0.084 11.1 0.3 0.12 10.5 0.3 1.1 1 0 0 1 1 1 0 BT1 family DUF2207 PF09972.9 ABK71717.1 - 0.19 10.4 0.1 0.22 10.3 0.1 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Abhydrolase_1 PF00561.20 ABK71718.1 - 3.4e-18 66.2 0.0 1.1e-09 38.4 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK71718.1 - 2.8e-16 60.8 6.6 3.7e-16 60.4 6.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK71718.1 - 7.7e-13 48.3 0.0 1.3e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 ABK71718.1 - 0.00017 21.2 0.0 0.0012 18.4 0.0 2.2 3 0 0 3 3 3 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 ABK71718.1 - 0.0057 16.2 0.1 4.4 6.7 0.0 2.8 3 1 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 ABK71718.1 - 0.0087 16.2 0.0 0.022 14.9 0.0 1.6 2 0 0 2 2 2 1 TAP-like protein Thioesterase PF00975.20 ABK71718.1 - 0.016 15.4 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain UPF0102 PF02021.17 ABK71719.1 - 9.1e-29 99.5 0.1 1.1e-28 99.3 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0102 NucS PF01939.16 ABK71719.1 - 0.0083 15.5 0.0 0.01 15.2 0.0 1.1 1 0 0 1 1 1 1 Endonuclease NucS DUF234 PF03008.14 ABK71719.1 - 0.02 15.3 0.0 0.027 14.9 0.0 1.3 1 0 0 1 1 1 0 Archaea bacterial proteins of unknown function Mrr_cat PF04471.12 ABK71719.1 - 0.091 12.8 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease adh_short PF00106.25 ABK71720.1 - 4.9e-43 146.9 0.1 6.8e-43 146.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK71720.1 - 1e-29 103.7 0.5 1.5e-29 103.3 0.5 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK71720.1 - 6.8e-13 48.9 0.1 1.3e-12 48.0 0.0 1.4 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 ABK71720.1 - 0.0017 17.5 0.0 0.0022 17.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 ABK71720.1 - 0.0046 16.5 0.0 0.01 15.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 ABK71720.1 - 0.007 16.5 0.0 0.95 9.6 0.0 2.3 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase RmlD_sub_bind PF04321.17 ABK71720.1 - 0.038 13.1 0.0 0.064 12.4 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Spore_III_AB PF09548.10 ABK71720.1 - 0.097 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Hydrolase_6 PF13344.6 ABK71721.1 - 3.3e-22 78.5 0.0 7.8e-22 77.3 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase GNAT_like PF18407.1 ABK71721.1 - 2.3e-18 66.3 2.7 2.3e-18 66.3 2.7 3.0 3 0 0 3 3 3 1 GCN5-related N-acetyltransferase like domain Hydrolase_like PF13242.6 ABK71721.1 - 3.1e-16 59.2 0.1 1.2e-15 57.3 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 ABK71721.1 - 3.9e-06 27.3 0.2 6e-06 26.7 0.2 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase FAD_oxidored PF12831.7 ABK71722.1 - 1.3e-95 321.3 3.1 2.5e-95 320.4 3.1 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 ABK71722.1 - 1.8e-06 27.8 7.6 3.6e-06 26.8 2.9 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ABK71722.1 - 3.7e-06 27.1 2.2 1.1e-05 25.5 2.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ABK71722.1 - 4.5e-06 26.1 1.2 8.8e-06 25.1 1.2 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 ABK71722.1 - 5.2e-06 25.8 6.9 5.2e-06 25.8 6.9 2.6 2 1 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 ABK71722.1 - 5.3e-06 25.4 1.7 8.4e-06 24.7 1.7 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 ABK71722.1 - 6.5e-06 25.5 5.1 1.2e-05 24.6 5.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 ABK71722.1 - 9.9e-06 25.0 1.8 2e-05 24.0 1.6 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ABK71722.1 - 0.00013 21.3 0.4 0.00022 20.6 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 ABK71722.1 - 0.00014 22.4 0.7 0.0012 19.3 0.7 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ABK71722.1 - 0.0032 16.8 1.1 0.0049 16.2 1.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ABK71722.1 - 0.044 12.8 2.0 1.1 8.3 0.3 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Patatin PF01734.22 ABK71722.1 - 2.6 8.2 7.8 5.1 7.2 7.7 1.7 1 1 0 1 1 1 0 Patatin-like phospholipase DNA_pol_A PF00476.20 ABK71724.1 - 1.8e-146 488.0 0.0 2.5e-146 487.6 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family A 5_3_exonuc_N PF02739.16 ABK71724.1 - 2.5e-54 183.5 0.0 5.1e-54 182.5 0.0 1.6 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 ABK71724.1 - 5.6e-27 94.2 0.0 1.4e-26 93.0 0.0 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold NYN_YacP PF05991.11 ABK71724.1 - 0.0081 16.1 0.0 0.04 13.9 0.0 2.1 2 0 0 2 2 2 1 YacP-like NYN domain HHH_5 PF14520.6 ABK71724.1 - 0.014 16.0 0.0 0.094 13.3 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain HHH_2 PF12826.7 ABK71724.1 - 0.018 15.2 0.0 0.096 12.8 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif CNV-Replicase_N PF16688.5 ABK71724.1 - 0.036 14.4 0.0 0.08 13.3 0.0 1.5 1 0 0 1 1 1 0 Replicase polyprotein N-term from Coronavirus nsp1 DUF2490 PF10677.9 ABK71724.1 - 0.14 12.1 0.0 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2490) Fer4 PF00037.27 ABK71726.1 - 1.7e-10 40.2 17.6 1.3e-08 34.3 5.7 2.5 2 1 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 ABK71726.1 - 2.1e-06 28.5 4.5 0.00018 22.3 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 ABK71726.1 - 9.7e-06 25.6 5.5 9.3e-05 22.5 0.1 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 ABK71726.1 - 1.8e-05 25.2 13.2 0.00055 20.5 13.9 2.2 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 ABK71726.1 - 0.00015 21.7 4.9 0.00015 21.7 4.9 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_4 PF12800.7 ABK71726.1 - 0.00026 21.3 2.0 0.00026 21.3 2.0 2.5 2 1 0 2 2 2 1 4Fe-4S binding domain Fer4_17 PF13534.6 ABK71726.1 - 0.00032 21.2 3.0 0.0017 18.8 0.1 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 ABK71726.1 - 0.00042 20.4 10.6 0.001 19.1 10.7 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 ABK71726.1 - 0.00081 19.8 5.2 0.0019 18.6 0.1 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 ABK71726.1 - 0.0012 18.8 3.7 0.0012 18.8 3.7 2.7 2 1 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.6 ABK71726.1 - 0.0022 18.1 16.1 0.033 14.3 16.2 2.0 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_3 PF12798.7 ABK71726.1 - 0.26 12.3 16.7 0.24 12.4 7.1 2.8 2 1 0 2 2 2 0 4Fe-4S binding domain Fer4_13 PF13370.6 ABK71726.1 - 6 7.5 15.9 5 7.7 7.1 2.6 2 1 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Patatin PF01734.22 ABK71727.1 - 5.2e-28 98.6 0.7 1e-27 97.7 0.7 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase Abhydrolase_1 PF00561.20 ABK71728.1 - 1e-23 84.3 0.0 1.3e-17 64.3 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Trans_reg_C PF00486.28 ABK71728.1 - 4.1e-17 62.0 0.0 6.8e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Hydrolase_4 PF12146.8 ABK71728.1 - 4.3e-15 55.6 0.0 9.4e-15 54.5 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 ABK71728.1 - 4.8e-06 25.5 0.0 9.7e-06 24.5 0.0 1.4 1 1 0 1 1 1 1 Ndr family Ser_hydrolase PF06821.13 ABK71728.1 - 0.00037 20.4 0.1 0.17 11.7 0.1 2.5 1 1 0 1 1 1 1 Serine hydrolase Palm_thioest PF02089.15 ABK71728.1 - 0.0053 16.6 0.0 0.0079 16.1 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Esterase PF00756.20 ABK71728.1 - 0.0065 16.1 0.0 0.0098 15.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 ABK71728.1 - 0.0084 15.6 0.0 0.15 11.6 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 ABK71728.1 - 0.043 13.6 0.0 0.59 9.9 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 ABK71728.1 - 0.099 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein AXE1 PF05448.12 ABK71728.1 - 0.11 11.2 0.0 0.42 9.2 0.0 1.8 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 ABK71728.1 - 0.11 12.3 0.0 9.4 6.0 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_M20 PF01546.28 ABK71729.1 - 5.8e-32 111.1 0.5 9.2e-32 110.4 0.5 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ABK71729.1 - 5.7e-11 42.3 1.2 7.2e-11 42.0 0.0 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 ABK71729.1 - 0.057 13.1 0.2 0.088 12.5 0.2 1.3 1 0 0 1 1 1 0 Peptidase family M28 LytTR PF04397.15 ABK71730.1 - 1e-18 67.4 0.0 1.5e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 LytTr DNA-binding domain GAF PF01590.26 ABK71730.1 - 0.0053 17.4 0.0 0.015 16.0 0.0 1.8 1 1 0 1 1 1 1 GAF domain Usp PF00582.26 ABK71731.1 - 6.4e-26 91.6 7.4 5.3e-17 62.7 3.2 2.1 2 0 0 2 2 2 2 Universal stress protein family DUF3152 PF11350.8 ABK71732.1 - 5.6e-101 336.5 0.0 6.8e-101 336.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3152) Zn_peptidase PF04228.13 ABK71732.1 - 0.063 12.7 0.4 0.16 11.4 0.0 1.8 3 0 0 3 3 3 0 Putative neutral zinc metallopeptidase Big_9 PF17963.1 ABK71732.1 - 0.14 13.0 4.0 0.16 12.7 1.6 2.2 2 0 0 2 2 2 0 Bacterial Ig domain Methyltransf_24 PF13578.6 ABK71734.1 - 1.2e-08 35.9 0.0 3.4e-08 34.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK71734.1 - 0.00067 20.4 0.0 0.0014 19.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.12 ABK71734.1 - 0.0023 17.6 0.0 0.0031 17.2 0.0 1.3 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_3 PF01596.17 ABK71734.1 - 0.009 15.2 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase TylF PF05711.11 ABK71734.1 - 0.012 14.9 0.1 3.9 6.7 0.0 2.2 2 0 0 2 2 2 0 Macrocin-O-methyltransferase (TylF) Methyltransf_25 PF13649.6 ABK71734.1 - 0.043 14.5 0.0 0.091 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Trns_repr_metal PF02583.17 ABK71735.1 - 6.4e-25 87.3 0.4 7.1e-25 87.2 0.4 1.0 1 0 0 1 1 1 1 Metal-sensitive transcriptional repressor SbcCD_C PF13558.6 ABK71736.1 - 7.7e-22 77.3 1.5 2.2e-21 75.9 0.3 2.5 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 ABK71736.1 - 1.9e-13 49.9 1.0 3.2e-13 49.2 0.3 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 ABK71736.1 - 9.8e-05 22.9 1.0 0.00044 20.8 0.0 2.7 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 ABK71736.1 - 0.014 15.9 0.2 0.58 10.7 0.0 3.4 3 0 0 3 3 3 0 ABC transporter AAA_18 PF13238.6 ABK71736.1 - 0.027 15.0 1.7 0.2 12.2 0.0 3.2 2 1 0 3 3 3 0 AAA domain DUF724 PF05266.14 ABK71736.1 - 3.6 7.4 8.8 16 5.3 0.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF724) Rhodanese PF00581.20 ABK71737.1 - 2.6e-07 31.1 0.0 3.3e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain IU_nuc_hydro PF01156.19 ABK71738.1 - 4.9e-84 282.5 0.2 5.6e-84 282.3 0.2 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase RNA_pol_A_CTD PF03118.15 ABK71739.1 - 2e-26 91.5 0.0 3.3e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain RNA_pol_A_bac PF01000.26 ABK71739.1 - 8e-26 90.6 0.0 1.7e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 ABK71739.1 - 8.9e-20 69.9 0.0 1.4e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L_2 PF13656.6 ABK71739.1 - 0.18 11.6 0.0 7.7 6.4 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain adh_short_C2 PF13561.6 ABK71740.1 - 1.8e-66 224.0 2.2 2.3e-66 223.7 2.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK71740.1 - 2.5e-54 183.7 1.4 2.9e-54 183.5 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK71740.1 - 2.3e-13 50.5 0.8 3.3e-13 49.9 0.8 1.1 1 0 0 1 1 1 1 KR domain MTS PF05175.14 ABK71740.1 - 0.078 12.5 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DinB_2 PF12867.7 ABK71741.1 - 0.022 15.3 0.5 0.044 14.3 0.5 1.5 1 0 0 1 1 1 0 DinB superfamily Glyco_hydr_30_2 PF14587.6 ABK71741.1 - 0.069 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 O-Glycosyl hydrolase family 30 Phage_holin_2_3 PF16080.5 ABK71741.1 - 4 7.3 8.5 6 6.7 0.0 2.3 1 1 1 2 2 2 0 Bacteriophage holin family HP1 MLTR_LBD PF17765.1 ABK71742.1 - 2.9e-55 187.0 2.8 2.9e-55 187.0 2.8 1.8 1 1 1 2 2 2 1 MmyB-like transcription regulator ligand binding domain HTH_31 PF13560.6 ABK71742.1 - 9.4e-16 57.9 9.3 2.8e-15 56.4 9.3 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 ABK71742.1 - 1.4e-07 31.5 0.0 3.2e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 ABK71742.1 - 0.014 15.9 0.0 0.031 14.7 0.0 1.6 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Bac_luciferase PF00296.20 ABK71744.1 - 2.3e-67 227.7 11.9 2.5e-67 227.5 11.9 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase TetR_N PF00440.23 ABK71745.1 - 5.3e-12 45.3 0.0 1.3e-11 44.0 0.0 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_14 PF17754.1 ABK71745.1 - 5e-07 29.7 0.2 9.2e-07 28.8 0.2 1.4 1 0 0 1 1 1 1 MftR C-terminal domain HTH_23 PF13384.6 ABK71745.1 - 0.00074 19.2 0.1 0.0054 16.5 0.1 2.4 2 1 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 ABK71745.1 - 0.0017 17.8 0.0 0.0052 16.2 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_24 PF13412.6 ABK71745.1 - 0.012 15.2 0.0 0.16 11.5 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 ABK71745.1 - 0.016 15.1 0.0 0.094 12.7 0.0 2.3 2 0 0 2 2 2 0 HTH domain HTH_AsnC-type PF13404.6 ABK71745.1 - 0.033 14.0 0.2 2.7 7.9 0.0 3.0 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain Sigma70_r4_2 PF08281.12 ABK71745.1 - 0.066 12.9 0.0 0.81 9.4 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_Tnp_1_2 PF13022.6 ABK71745.1 - 0.068 13.3 0.0 0.26 11.4 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix of insertion element transposase CDP-OH_P_transf PF01066.21 ABK71746.1 - 9.9e-14 51.9 0.2 9.9e-14 51.9 0.2 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase MaoC_dehydratas PF01575.19 ABK71747.1 - 3.9e-29 100.7 0.1 4.8e-29 100.4 0.1 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 ABK71747.1 - 5.1e-08 33.1 0.1 9.2e-08 32.3 0.1 1.4 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase DUF4403 PF14356.6 ABK71747.1 - 0.0036 16.0 0.1 0.035 12.8 0.1 1.9 1 1 0 2 2 2 1 Domain of unknown function (DUF4403) DUF5045 PF16464.5 ABK71747.1 - 0.14 12.5 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5045) UTRA PF07702.13 ABK71748.1 - 1.7e-31 109.0 1.3 4.3e-31 107.6 0.3 1.9 2 0 0 2 2 2 1 UTRA domain GntR PF00392.21 ABK71748.1 - 1.2e-11 44.0 0.9 3.9e-11 42.4 0.9 1.9 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 ABK71748.1 - 3.9e-05 23.5 0.0 7.6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_DeoR PF08220.12 ABK71748.1 - 0.008 15.9 0.2 0.017 14.8 0.2 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain Sigma70_r4 PF04545.16 ABK71748.1 - 0.0081 15.7 0.1 0.021 14.3 0.1 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_15 PF12324.8 ABK71748.1 - 0.0095 15.9 0.1 0.048 13.6 0.2 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain of alkylmercury lyase MarR_2 PF12802.7 ABK71748.1 - 0.0097 15.8 0.7 0.031 14.2 0.7 1.9 1 0 0 1 1 1 1 MarR family HTH_28 PF13518.6 ABK71748.1 - 0.044 13.9 0.2 0.11 12.6 0.2 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain AbiEi_4 PF13338.6 ABK71748.1 - 0.062 13.5 1.5 0.062 13.5 1.5 1.9 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin Rrf2 PF02082.20 ABK71748.1 - 0.062 13.7 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator DUF977 PF06163.11 ABK71748.1 - 0.068 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) DUF4423 PF14394.6 ABK71748.1 - 0.095 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) RepL PF05732.11 ABK71748.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) TrmB PF01978.19 ABK71748.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Gamma_PGA_hydro PF05908.11 ABK71749.1 - 2.7e-41 141.1 0.0 3.8e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Poly-gamma-glutamate hydrolase AIG2_2 PF13772.6 ABK71749.1 - 7.6e-15 55.1 0.0 1.1e-13 51.3 0.0 2.1 2 0 0 2 2 2 1 AIG2-like family GGACT PF06094.12 ABK71749.1 - 1.6e-11 44.8 0.0 6.5e-11 42.9 0.0 1.9 2 0 0 2 2 2 1 Gamma-glutamyl cyclotransferase, AIG2-like PCRF PF03462.18 ABK71750.1 - 3.3e-63 213.0 0.6 3.3e-62 209.8 0.0 2.0 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 ABK71750.1 - 1.2e-39 134.8 2.1 2e-39 134.1 2.1 1.3 1 0 0 1 1 1 1 RF-1 domain ABC_tran_CTD PF16326.5 ABK71750.1 - 0.00063 19.9 12.7 0.044 14.0 0.0 3.5 3 0 0 3 3 3 2 ABC transporter C-terminal domain Pox_A_type_inc PF04508.12 ABK71750.1 - 0.053 13.4 0.7 17 5.5 0.0 2.8 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Seryl_tRNA_N PF02403.22 ABK71750.1 - 3.3 8.0 7.2 0.77 10.0 0.2 2.8 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain HAD_2 PF13419.6 ABK71751.1 - 0.00015 21.9 0.0 0.00017 21.7 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 ABK71751.1 - 0.00032 21.2 0.1 0.00062 20.2 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ABK71751.1 - 0.0036 17.6 0.0 0.0045 17.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Epimerase PF01370.21 ABK71753.1 - 8.6e-53 179.3 0.0 1e-52 179.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ABK71753.1 - 1e-32 113.9 0.0 2.9e-32 112.4 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ABK71753.1 - 6.5e-19 68.0 0.0 8.1e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ABK71753.1 - 6.2e-13 48.5 0.0 1.1e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 ABK71753.1 - 3.1e-12 46.8 0.0 6.7e-12 45.7 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 ABK71753.1 - 2.2e-11 43.4 0.0 4.1e-09 36.0 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 ABK71753.1 - 2.9e-08 33.2 0.0 6.9e-07 28.7 0.0 2.5 3 1 0 3 3 3 1 Polysaccharide biosynthesis protein NmrA PF05368.13 ABK71753.1 - 0.005 16.4 0.0 0.017 14.7 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 ABK71753.1 - 0.0091 15.5 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK71753.1 - 0.013 15.5 0.1 0.034 14.1 0.1 1.8 1 1 0 1 1 1 0 KR domain bPH_6 PF10756.9 ABK71754.1 - 0.0088 16.1 0.2 0.056 13.5 0.0 2.2 2 0 0 2 2 2 1 Bacterial PH domain DUF1616 PF07760.11 ABK71754.1 - 8.6 5.6 7.7 20 4.4 1.4 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF1616) SBP_bac_1 PF01547.25 ABK71755.1 - 4.5e-40 138.5 13.9 6.9e-40 137.9 13.9 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 ABK71755.1 - 2.7e-36 125.8 8.0 3.7e-36 125.4 8.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 ABK71755.1 - 9.1e-07 28.5 2.4 7.8e-06 25.5 2.4 2.1 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 ABK71755.1 - 0.00082 19.2 3.9 0.00082 19.2 3.9 1.9 2 1 0 2 2 2 1 Bacterial extracellular solute-binding protein LysR_substrate PF03466.20 ABK71755.1 - 0.014 14.8 0.0 0.047 13.0 0.0 1.8 2 0 0 2 2 2 0 LysR substrate binding domain Cupin_2 PF07883.11 ABK71756.1 - 1.4e-07 31.1 0.2 1.3e-06 28.0 0.0 2.6 3 0 0 3 3 3 1 Cupin domain Big_3_5 PF16640.5 ABK71756.1 - 0.0043 17.2 0.2 0.01 16.0 0.2 1.6 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 3) AraC_binding PF02311.19 ABK71756.1 - 0.098 12.6 0.0 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 AraC-like ligand binding domain LysR_substrate PF03466.20 ABK71757.1 - 1.3e-34 119.4 5.5 1.8e-34 118.9 5.5 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 ABK71757.1 - 2.1e-23 82.0 0.8 5.2e-23 80.8 0.8 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family PDU_like PF15953.5 ABK71758.1 - 0.056 13.5 0.0 0.082 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative propanediol utilisation SicP-binding PF09119.10 ABK71758.1 - 0.14 12.2 0.0 0.38 10.8 0.0 1.7 2 0 0 2 2 2 0 SicP binding CAP_N PF01213.19 ABK71758.1 - 0.48 9.9 2.0 0.63 9.5 2.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal MarR_2 PF12802.7 ABK71759.1 - 9.6e-09 35.0 0.8 9.6e-09 35.0 0.8 2.2 3 0 0 3 3 3 1 MarR family MarR PF01047.22 ABK71759.1 - 1.4e-08 34.5 0.1 4.7e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 ABK71759.1 - 1.2e-05 25.7 0.5 3e-05 24.4 0.1 1.9 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_24 PF13412.6 ABK71759.1 - 7.1e-05 22.3 0.0 0.00016 21.2 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 ABK71759.1 - 0.059 13.2 1.3 0.22 11.4 0.1 2.4 2 0 0 2 2 2 0 IclR helix-turn-helix domain FAD_binding_2 PF00890.24 ABK71760.1 - 1.2e-44 153.1 7.6 1e-42 146.7 7.6 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 ABK71760.1 - 6.5e-12 45.7 6.7 8.8e-11 42.0 6.7 2.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ABK71760.1 - 3.7e-06 26.6 2.3 6.3e-06 25.8 2.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ABK71760.1 - 0.00013 21.3 0.3 0.00013 21.3 0.3 3.1 4 1 1 5 5 5 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ABK71760.1 - 0.00016 20.5 3.7 0.00032 19.5 3.7 1.5 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 ABK71760.1 - 0.0013 18.9 3.1 0.004 17.3 3.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 ABK71760.1 - 0.0034 16.7 1.2 0.018 14.3 0.6 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 ABK71760.1 - 0.014 14.7 5.7 0.026 13.8 4.0 2.0 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 ABK71760.1 - 0.024 13.7 5.2 0.1 11.6 5.9 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.27 ABK71760.1 - 0.038 14.6 0.2 11 6.7 0.5 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ABK71760.1 - 0.047 12.9 1.4 0.088 12.0 1.4 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase LPD22 PF18834.1 ABK71760.1 - 0.072 13.3 0.9 5.7 7.2 0.0 2.8 3 0 0 3 3 3 0 Large polyvalent protein associated domain 22 AlaDh_PNT_C PF01262.21 ABK71760.1 - 0.25 10.6 1.4 0.45 9.8 1.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain F420H2_quin_red PF04075.14 ABK71761.1 - 1.5e-07 31.6 0.5 1.9e-07 31.3 0.5 1.2 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase MR_MLE_C PF13378.6 ABK71762.1 - 2.3e-22 79.7 1.9 4.6e-22 78.7 1.9 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like Enolase_like_N PF18374.1 ABK71762.1 - 1.2e-08 34.2 0.8 3.5e-08 32.7 0.8 1.9 1 1 0 1 1 1 1 Enolase N-terminal domain-like DDE_3 PF13358.6 ABK71763.1 - 6.5e-24 84.4 0.0 9.8e-24 83.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.6 ABK71763.1 - 3.9e-15 55.6 0.2 1.5e-14 53.8 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 ABK71763.1 - 1.1e-12 47.9 4.7 3.6e-11 43.0 0.2 2.8 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_23 PF13384.6 ABK71763.1 - 1.9e-11 43.4 1.1 1.2e-10 40.9 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 ABK71763.1 - 8.2e-10 39.2 0.1 3.6e-09 37.1 0.0 2.1 1 1 1 2 2 2 1 Homeodomain-like domain HTH_50 PF18024.1 ABK71763.1 - 6e-07 29.0 0.1 1.7e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 ABK71763.1 - 2.7e-06 27.8 0.1 6.2e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 leucine-zipper of insertion element IS481 HTH_Tnp_1 PF01527.20 ABK71763.1 - 0.027 14.8 0.1 0.096 13.0 0.0 2.0 2 0 0 2 2 2 0 Transposase HTH_1 PF00126.27 ABK71763.1 - 0.058 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_6 PF01418.17 ABK71763.1 - 0.079 12.9 0.0 2.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family Seryl_tRNA_N PF02403.22 ABK71764.1 - 3.1e-25 88.5 2.0 4.4e-25 88.0 2.0 1.2 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain tRNA-synt_2b PF00587.25 ABK71764.1 - 1.4e-24 87.0 0.0 2.1e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) THDPS_M PF14789.6 ABK71765.1 - 4.3e-19 68.3 0.0 1e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 Tetrahydrodipicolinate N-succinyltransferase middle Hexapep_2 PF14602.6 ABK71765.1 - 2.6e-14 52.7 2.6 2.6e-14 52.7 2.6 2.8 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 ABK71765.1 - 0.0011 18.6 5.7 0.014 15.1 0.2 3.1 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) DDE_Tnp_1 PF01609.21 ABK71766.1 - 1.9e-13 50.5 0.0 6.9e-13 48.7 0.0 1.8 1 1 0 1 1 1 1 Transposase DDE domain COXG PF06240.13 ABK71767.1 - 5e-15 55.5 0.0 6.1e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Carbon monoxide dehydrogenase subunit G (CoxG) Polyketide_cyc2 PF10604.9 ABK71767.1 - 0.00014 22.1 0.2 0.00025 21.4 0.2 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Fer4_15 PF13459.6 ABK71768.1 - 9.7e-17 61.5 1.2 1.1e-16 61.3 1.2 1.0 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_13 PF13370.6 ABK71768.1 - 3.5e-13 49.9 1.0 3.9e-13 49.7 1.0 1.0 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_19 PF06902.11 ABK71768.1 - 0.037 14.1 0.7 0.1 12.7 0.7 1.6 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Polysacc_deac_1 PF01522.21 ABK71769.1 - 1.8e-14 53.7 0.1 2.9e-14 53.0 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 ABK71769.1 - 0.00041 20.1 0.0 0.00064 19.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) BPD_transp_1 PF00528.22 ABK71771.1 - 8.2e-28 97.4 13.5 8.2e-28 97.4 13.5 1.5 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 ABK71771.1 - 2.1e-09 37.2 0.1 2.1e-09 37.2 0.1 3.4 5 0 0 5 5 5 1 N-terminal TM domain of oligopeptide transport permease C PsbL PF02419.17 ABK71771.1 - 0.8 9.7 4.9 1.1 9.3 0.3 2.8 2 0 0 2 2 2 0 PsbL protein SnoaL_4 PF13577.6 ABK71772.1 - 1.9e-30 105.6 0.6 2.3e-30 105.3 0.6 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 ABK71772.1 - 0.059 13.6 0.3 0.16 12.2 0.3 1.8 1 1 0 1 1 1 0 SnoaL-like domain SnoaL_2 PF12680.7 ABK71772.1 - 0.075 13.7 1.5 0.14 12.8 1.4 1.8 1 1 0 1 1 1 0 SnoaL-like domain NHL PF01436.21 ABK71773.1 - 2.3e-26 90.4 13.2 3.6e-05 23.6 0.2 6.9 7 0 0 7 7 7 6 NHL repeat ketoacyl-synt PF00109.26 ABK71774.1 - 2.2e-81 273.2 3.3 4.4e-81 272.2 0.1 3.0 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 ABK71774.1 - 9.9e-52 176.4 0.0 2e-51 175.4 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 ABK71774.1 - 1.6e-42 144.2 0.1 4e-42 143.0 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 ABK71774.1 - 1.6e-20 73.2 0.5 1.1e-09 38.5 0.1 4.1 4 0 0 4 4 4 2 Phosphopantetheine attachment site Thioesterase PF00975.20 ABK71774.1 - 6.5e-19 69.0 0.0 2.5e-18 67.0 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain KAsynt_C_assoc PF16197.5 ABK71774.1 - 9.4e-12 45.4 0.0 3.6e-11 43.5 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 ABK71774.1 - 5.3e-06 26.0 0.2 2.6e-05 23.7 0.2 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain Lipase_3 PF01764.25 ABK71774.1 - 0.0015 18.4 0.1 0.095 12.6 0.0 2.7 2 0 0 2 2 2 1 Lipase (class 3) DUF2974 PF11187.8 ABK71774.1 - 0.0017 18.0 0.0 0.0037 16.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 ABK71774.1 - 0.0076 16.9 0.0 0.0076 16.9 0.0 5.0 5 1 0 5 5 5 1 Alpha/beta hydrolase family AA_kinase PF00696.28 ABK71775.1 - 9e-35 120.4 4.3 1.3e-34 119.8 4.3 1.3 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 ABK71775.1 - 8.2e-20 70.5 0.9 1.7e-18 66.3 0.1 2.9 3 0 0 3 3 3 1 PUA domain PUA_3 PF17785.1 ABK71775.1 - 0.01 15.6 0.4 0.26 11.2 0.0 2.9 3 0 0 3 3 3 0 PUA-like domain ACT_7 PF13840.6 ABK71775.1 - 0.11 12.3 0.2 0.28 11.0 0.2 1.7 1 0 0 1 1 1 0 ACT domain Radical_SAM PF04055.21 ABK71776.1 - 7.2e-12 46.0 0.0 1.2e-11 45.2 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily MID_pPIWI_RE PF18157.1 ABK71776.1 - 0.042 14.1 0.5 0.64 10.3 0.0 2.6 2 1 0 2 2 2 0 MID domain of pPIWI_RE AIRS PF00586.24 ABK71777.1 - 5e-18 65.6 0.9 5e-18 65.6 0.9 2.2 3 1 0 3 3 3 1 AIR synthase related protein, N-terminal domain AIRS_C PF02769.22 ABK71777.1 - 1.5e-17 64.1 2.4 6.1e-17 62.2 2.4 1.9 1 1 0 1 1 1 1 AIR synthase related protein, C-terminal domain HTH_20 PF12840.7 ABK71777.1 - 0.046 13.8 0.1 0.093 12.8 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain NADHdh PF00146.21 ABK71778.1 - 1.3e-122 408.9 20.4 1.3e-122 408.9 20.4 1.7 2 0 0 2 2 2 1 NADH dehydrogenase DUF3043 PF11241.8 ABK71778.1 - 4.2 7.4 5.6 13 5.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3043) DUF4083 PF13314.6 ABK71778.1 - 5 7.2 5.1 47 4.0 1.7 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) Bac_luciferase PF00296.20 ABK71779.1 - 2.6e-63 214.3 5.4 6.8e-63 213.0 5.4 1.6 1 1 0 1 1 1 1 Luciferase-like monooxygenase Thioredox_DsbH PF03190.15 ABK71779.1 - 0.066 13.2 0.0 9.2 6.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF255 Acyl-CoA_dh_1 PF00441.24 ABK71780.1 - 3.9e-44 150.5 2.1 5.9e-44 149.9 2.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK71780.1 - 5e-21 74.7 0.0 9.9e-21 73.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ABK71780.1 - 1.4e-14 54.5 0.1 2e-14 54.0 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK71780.1 - 2.3e-12 47.6 0.4 3.2e-11 43.9 0.4 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_ox_N PF14749.6 ABK71780.1 - 0.0014 19.2 0.0 0.0025 18.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Amidohydro_2 PF04909.14 ABK71781.1 - 5.5e-22 78.9 9.0 7.1e-22 78.5 9.0 1.3 1 1 0 1 1 1 1 Amidohydrolase CitMHS PF03600.16 ABK71782.1 - 0.073 12.3 1.0 0.097 11.8 1.0 1.2 1 0 0 1 1 1 0 Citrate transporter Phage_holin_3_6 PF07332.11 ABK71782.1 - 3.2 7.8 12.4 1.5 8.9 9.8 1.8 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF3185 PF11381.8 ABK71783.1 - 0.21 11.6 3.8 9.2 6.4 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) DUF3784 PF12650.7 ABK71783.1 - 0.29 11.4 2.6 0.52 10.5 2.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3784) Phage_holin_3_6 PF07332.11 ABK71783.1 - 0.76 9.8 4.4 1.1 9.3 4.4 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF3040 PF11239.8 ABK71783.1 - 1 9.6 4.5 3.2 8.1 4.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) DUF202 PF02656.15 ABK71783.1 - 5.6 7.5 9.3 2.7 8.5 1.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF202) DUF3263 PF11662.8 ABK71784.1 - 1.1e-36 124.5 2.5 1.3e-36 124.3 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3263) 3HCDH_N PF02737.18 ABK71785.1 - 2.7e-61 206.6 0.3 4.7e-61 205.8 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 ABK71785.1 - 1.7e-33 115.1 0.1 6.3e-32 110.1 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 ABK71785.1 - 5.7e-05 23.3 0.6 0.00012 22.2 0.6 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 ABK71785.1 - 0.00078 18.9 0.3 0.0016 17.9 0.3 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 ABK71785.1 - 0.0065 17.0 0.1 0.014 16.0 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_8 PF13450.6 ABK71785.1 - 0.0078 16.4 0.4 0.018 15.2 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain PALP PF00291.25 ABK71785.1 - 0.023 14.1 0.1 0.031 13.7 0.1 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Shikimate_DH PF01488.20 ABK71785.1 - 0.026 14.6 0.5 1.4 9.0 0.1 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 ABK71785.1 - 0.041 13.1 0.3 0.056 12.7 0.3 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ABK71785.1 - 0.048 12.9 0.1 0.059 12.6 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 ABK71785.1 - 0.053 13.1 0.1 0.086 12.4 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 ABK71785.1 - 0.1 12.9 1.3 0.48 10.7 1.3 2.1 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 ABK71785.1 - 0.13 12.3 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Acyl_transf_3 PF01757.22 ABK71786.1 - 9.5e-12 44.6 32.9 9.5e-12 44.6 32.9 1.4 2 0 0 2 2 2 1 Acyltransferase family tRNA-synt_2c PF01411.19 ABK71787.1 - 5.1e-203 675.6 0.0 6.2e-203 675.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) DHHA1 PF02272.19 ABK71787.1 - 3.9e-19 69.4 6.5 3.9e-19 69.4 6.5 2.4 3 0 0 3 3 3 1 DHHA1 domain tRNA_SAD PF07973.14 ABK71787.1 - 1.9e-15 56.7 0.5 3.5e-15 55.8 0.5 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain ACR_tran PF00873.19 ABK71787.1 - 0.00032 18.5 0.0 0.0005 17.9 0.0 1.2 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family HTH_18 PF12833.7 ABK71788.1 - 1.7e-24 85.9 1.7 3e-24 85.1 1.7 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 ABK71788.1 - 7.5e-10 38.7 0.1 4.8e-06 26.5 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Cupin_2 PF07883.11 ABK71788.1 - 5.2e-05 22.9 0.5 8.1e-05 22.3 0.5 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 ABK71788.1 - 6.3e-05 22.9 0.3 0.00018 21.4 0.1 1.8 2 0 0 2 2 2 1 AraC-like ligand binding domain AraC_binding_2 PF14525.6 ABK71788.1 - 0.0017 18.1 0.1 0.0017 18.1 0.1 1.8 2 0 0 2 2 2 1 AraC-binding-like domain HTH_31 PF13560.6 ABK71788.1 - 0.036 14.4 0.3 0.072 13.4 0.3 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 ABK71788.1 - 0.096 12.5 1.7 1.3 8.9 0.2 2.5 1 1 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 ABK71788.1 - 9 5.8 7.3 2.4 7.7 0.3 2.9 3 1 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 PDH PF02153.17 ABK71789.1 - 2.7e-40 138.0 0.0 3.4e-40 137.7 0.0 1.0 1 0 0 1 1 1 1 Prephenate dehydrogenase 2-Hacid_dh_C PF02826.19 ABK71789.1 - 9.4e-07 28.4 0.4 0.00024 20.5 0.1 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 ABK71789.1 - 4e-05 23.8 0.5 0.00011 22.4 0.3 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ABK71789.1 - 0.00053 20.5 0.4 0.0015 19.0 0.4 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_3 PF03447.16 ABK71789.1 - 0.014 16.0 0.5 0.44 11.2 0.0 2.6 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain LigB PF02900.18 ABK71791.1 - 2.7e-56 190.6 0.0 3.1e-56 190.4 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Adeno_terminal PF02459.15 ABK71793.1 - 0.65 8.3 3.0 0.72 8.2 3.0 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Response_reg PF00072.24 ABK71794.1 - 5.6e-27 94.1 0.1 7.9e-27 93.6 0.1 1.2 1 0 0 1 1 1 1 Response regulator receiver domain CitT PF12431.8 ABK71794.1 - 6.7e-06 26.3 0.1 1.3e-05 25.4 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulator HTH_29 PF13551.6 ABK71794.1 - 0.0018 18.2 0.4 0.0076 16.2 0.4 2.1 2 0 0 2 2 2 1 Winged helix-turn helix DUF977 PF06163.11 ABK71794.1 - 0.0019 18.2 0.0 0.0043 17.0 0.0 1.6 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF977) HTH_IclR PF09339.10 ABK71794.1 - 0.037 13.8 0.1 0.11 12.3 0.1 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain Peripla_BP_3 PF13377.6 ABK71795.1 - 8.4e-35 120.6 2.6 5.7e-34 117.8 1.2 2.1 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 ABK71795.1 - 5.3e-20 72.0 0.0 7.3e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 ABK71795.1 - 8.9e-17 61.5 0.0 1.3e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain LacI PF00356.21 ABK71795.1 - 5.6e-12 45.3 1.5 5.6e-12 45.3 1.5 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family TetR_N PF00440.23 ABK71795.1 - 0.17 11.7 0.2 0.49 10.2 0.2 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family Aldedh PF00171.22 ABK71796.1 - 4.1e-147 490.4 0.0 4.7e-147 490.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MlaE PF02405.16 ABK71797.1 - 6.1e-55 186.2 26.6 7.6e-55 185.9 26.6 1.1 1 0 0 1 1 1 1 Permease MlaE AurF PF11583.8 ABK71798.1 - 1.6e-110 368.9 0.0 1.8e-110 368.7 0.0 1.0 1 0 0 1 1 1 1 P-aminobenzoate N-oxygenase AurF Metal_hydrol PF10118.9 ABK71798.1 - 0.0088 15.8 0.3 0.015 15.1 0.3 1.3 1 0 0 1 1 1 1 Predicted metal-dependent hydrolase Transketolase_N PF00456.21 ABK71799.1 - 2.2e-20 72.9 0.0 8.1e-12 44.7 0.0 2.2 2 0 0 2 2 2 2 Transketolase, thiamine diphosphate binding domain PDH_E1_M PF17831.1 ABK71799.1 - 5.3e-14 52.3 0.0 9.4e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Pyruvate dehydrogenase E1 component middle domain Transketolase_C PF02780.20 ABK71799.1 - 1e-05 25.4 0.0 7.7e-05 22.6 0.0 2.4 3 0 0 3 3 3 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 ABK71799.1 - 0.0002 20.6 0.0 0.0006 19.1 0.0 1.7 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TetR_N PF00440.23 ABK71800.1 - 8.2e-16 57.5 1.5 3.1e-14 52.5 0.2 3.0 3 0 0 3 3 3 1 Bacterial regulatory proteins, tetR family DUF2795 PF11387.8 ABK71800.1 - 0.37 11.0 3.5 17 5.7 0.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2795) ABC_tran PF00005.27 ABK71801.1 - 4.3e-29 101.8 0.0 5.5e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK71801.1 - 1.2e-10 41.7 0.0 9.4e-06 25.6 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ABK71801.1 - 0.00069 20.0 0.2 0.001 19.5 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 ABK71801.1 - 0.0046 17.5 0.0 0.0073 16.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ABK71801.1 - 0.0063 16.4 0.0 0.0094 15.9 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase DUF3606 PF12244.8 ABK71801.1 - 0.012 15.5 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) AAA_22 PF13401.6 ABK71801.1 - 0.019 15.3 1.6 0.14 12.5 1.6 2.3 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ABK71801.1 - 0.019 14.7 0.1 0.045 13.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 ABK71801.1 - 0.033 13.6 0.0 6.6 6.1 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain RNA_helicase PF00910.22 ABK71801.1 - 0.038 14.4 0.0 0.095 13.1 0.0 1.6 1 1 0 1 1 1 0 RNA helicase PduV-EutP PF10662.9 ABK71801.1 - 0.048 13.4 0.2 0.083 12.6 0.2 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 ABK71801.1 - 0.048 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ABK71801.1 - 0.067 12.9 1.0 0.11 12.2 1.0 1.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 ABK71801.1 - 0.073 13.5 0.6 0.14 12.6 0.6 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.25 ABK71801.1 - 0.084 12.5 0.0 0.087 12.5 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain ATPase_2 PF01637.18 ABK71801.1 - 0.12 12.3 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PRK PF00485.18 ABK71801.1 - 0.15 11.8 0.2 0.3 10.8 0.2 1.5 2 0 0 2 2 1 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.12 ABK71801.1 - 0.16 11.9 0.5 0.32 10.9 0.5 1.4 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 ABK71801.1 - 0.17 11.0 0.5 0.27 10.4 0.5 1.2 1 0 0 1 1 1 0 NB-ARC domain Adeno_IVa2 PF02456.15 ABK71801.1 - 0.19 10.5 0.3 0.32 9.8 0.3 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein Rad17 PF03215.15 ABK71801.1 - 0.33 10.8 0.4 0.55 10.1 0.4 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain Lsr2 PF11774.8 ABK71802.1 - 9.6e-15 54.7 6.7 3.2e-14 53.0 6.7 1.8 1 1 0 1 1 1 1 Lsr2 Smoa_sbd PF17885.1 ABK71803.1 - 4.9e-09 36.3 0.0 1.3e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Styrene monooxygenase A putative substrate binding domain IlvN PF07991.12 ABK71803.1 - 0.0017 17.9 0.0 0.0039 16.8 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Pyr_redox_2 PF07992.14 ABK71803.1 - 0.0021 17.3 0.0 0.0032 16.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 ABK71803.1 - 0.0071 16.9 0.1 0.015 15.8 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent FAD_binding_2 PF00890.24 ABK71803.1 - 0.0079 15.3 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ABK71803.1 - 0.011 16.0 0.1 0.035 14.3 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 ABK71803.1 - 0.016 15.6 0.0 0.038 14.4 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 ABK71803.1 - 0.016 14.4 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ABK71803.1 - 0.058 12.6 1.1 0.5 9.6 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.18 ABK71803.1 - 0.096 12.6 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DDE_3 PF13358.6 ABK71804.1 - 8.3e-24 84.0 0.0 1.3e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.6 ABK71804.1 - 3.7e-15 55.7 0.2 1.5e-14 53.8 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 ABK71804.1 - 1.2e-12 47.8 4.7 3.5e-11 43.1 0.2 2.8 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_23 PF13384.6 ABK71804.1 - 2.3e-11 43.1 1.9 1.2e-10 40.9 0.0 2.6 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 ABK71804.1 - 8.5e-10 39.1 0.1 3.5e-09 37.1 0.0 2.1 1 1 1 2 2 2 1 Homeodomain-like domain HTH_50 PF18024.1 ABK71804.1 - 5.8e-07 29.0 0.1 1.7e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 ABK71804.1 - 2.6e-06 27.8 0.1 6.1e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 leucine-zipper of insertion element IS481 HTH_Tnp_1 PF01527.20 ABK71804.1 - 0.027 14.8 0.2 0.093 13.1 0.0 1.9 2 0 0 2 2 2 0 Transposase HTH_1 PF00126.27 ABK71804.1 - 0.056 13.4 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_6 PF01418.17 ABK71804.1 - 0.08 12.9 0.0 2.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family rve_2 PF13333.6 ABK71804.1 - 0.18 12.0 0.0 2.5 8.3 0.0 2.2 2 0 0 2 2 2 0 Integrase core domain TetR_C_31 PF17940.1 ABK71805.1 - 4e-18 65.6 6.4 4e-18 65.6 6.4 2.0 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK71805.1 - 6.4e-08 32.3 0.2 1.3e-07 31.3 0.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 ABK71805.1 - 0.0013 19.0 3.4 0.0013 19.0 3.4 2.5 1 1 1 3 3 3 1 BetI-type transcriptional repressor, C-terminal RNA_GG_bind PF10258.9 ABK71805.1 - 0.069 13.2 0.1 13 5.9 0.0 2.7 3 0 0 3 3 3 0 PHAX RNA-binding domain Castor_Poll_mid PF06241.12 ABK71805.1 - 0.084 12.9 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Castor and Pollux, part of voltage-gated ion channel TetR_C_14 PF17754.1 ABK71805.1 - 2.7 8.0 9.0 0.47 10.4 1.0 2.8 3 1 0 3 3 3 0 MftR C-terminal domain TPP_enzyme_N PF02776.18 ABK71806.1 - 9.5e-38 129.5 0.1 9.5e-38 129.5 0.1 3.1 4 0 0 4 4 4 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 ABK71806.1 - 6.2e-33 113.8 2.9 3.4e-31 108.1 0.1 3.2 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 ABK71806.1 - 1.4e-06 28.1 0.2 2.9e-06 27.0 0.2 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 ABK71806.1 - 0.0012 18.6 0.9 0.0037 17.1 0.1 2.1 2 1 1 3 3 3 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PRiA4_ORF3 PF07929.11 ABK71807.1 - 2.1e-51 174.1 0.0 2.5e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein adh_short_C2 PF13561.6 ABK71808.1 - 1.7e-47 162.0 0.8 3.6e-47 160.9 0.8 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK71808.1 - 5e-44 150.1 0.1 9.2e-44 149.2 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 ABK71808.1 - 0.00012 22.1 0.4 0.00021 21.2 0.3 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ABK71808.1 - 0.00021 20.8 0.0 0.00039 19.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.21 ABK71808.1 - 0.00068 19.7 0.1 0.0011 19.0 0.1 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KR PF08659.10 ABK71808.1 - 0.0011 18.9 0.1 0.032 14.1 0.1 2.2 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 ABK71808.1 - 0.0023 18.2 0.6 0.004 17.4 0.6 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 ABK71808.1 - 0.0047 17.0 0.1 0.0076 16.3 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ADH_zinc_N PF00107.26 ABK71808.1 - 0.18 11.8 1.4 0.38 10.7 1.4 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase GMC_oxred_N PF00732.19 ABK71809.1 - 8.2e-73 245.3 0.0 1e-72 245.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ABK71809.1 - 5.1e-41 140.6 0.1 8.1e-41 139.9 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ABK71809.1 - 1.1e-07 31.4 3.5 3.8e-06 26.3 3.5 2.3 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 ABK71809.1 - 1.1e-06 27.9 0.1 1.8e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 ABK71809.1 - 1.2e-05 25.5 0.8 4.4e-05 23.6 0.8 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ABK71809.1 - 0.00049 19.8 4.2 0.0045 16.6 3.8 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ABK71809.1 - 0.0011 18.3 0.0 0.0053 16.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ABK71809.1 - 0.0081 15.4 0.3 0.042 13.1 0.1 1.9 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 ABK71809.1 - 0.0098 14.6 0.1 0.013 14.2 0.1 1.1 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 ABK71809.1 - 0.012 14.8 0.0 0.072 12.2 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 ABK71809.1 - 0.024 14.0 0.9 0.46 9.8 1.6 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 ABK71809.1 - 0.04 12.8 0.1 0.055 12.3 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 ABK71809.1 - 0.044 14.4 0.0 0.28 11.8 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ABK71809.1 - 0.063 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 ABK71809.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Amidohydro_1 PF01979.20 ABK71810.1 - 3e-15 56.4 0.0 5.8e-15 55.4 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ABK71810.1 - 2.7e-10 40.3 8.0 4.8e-07 29.6 4.9 2.7 2 1 0 2 2 2 2 Amidohydrolase family PEP_hydrolase PF09370.10 ABK71810.1 - 0.021 14.0 0.7 0.06 12.6 0.0 1.9 2 0 0 2 2 2 0 Phosphoenolpyruvate hydrolase-like Abhydrolase_1 PF00561.20 ABK71811.1 - 2.7e-22 79.7 0.0 1.3e-20 74.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ABK71811.1 - 2.1e-18 66.5 0.0 3.2e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ABK71811.1 - 2.2e-13 51.3 3.7 2.8e-13 51.0 3.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 ABK71811.1 - 0.00014 22.0 0.1 0.0003 21.0 0.1 1.5 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_4 PF08386.10 ABK71811.1 - 0.00045 20.3 0.0 0.00088 19.4 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.21 ABK71811.1 - 0.0017 17.9 0.0 0.62 9.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family FSH1 PF03959.13 ABK71811.1 - 0.006 16.3 0.0 0.013 15.2 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Ndr PF03096.14 ABK71811.1 - 0.018 13.8 0.0 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 Ndr family Abhydrolase_5 PF12695.7 ABK71811.1 - 0.15 11.8 0.0 0.9 9.3 0.1 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF915 PF06028.11 ABK71811.1 - 0.27 10.5 0.0 0.78 9.0 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Oxygenase-NA PF09859.9 ABK71812.1 - 4e-77 257.6 0.0 5.4e-77 257.2 0.0 1.2 1 0 0 1 1 1 1 Oxygenase, catalysing oxidative methylation of damaged DNA Sigma70_r2 PF04542.14 ABK71813.1 - 8e-18 64.0 0.1 1.7e-17 63.0 0.1 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 ABK71813.1 - 3.9e-16 58.5 0.1 8.6e-16 57.4 0.0 1.6 1 1 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 ABK71813.1 - 3.2e-10 39.4 0.1 7.6e-10 38.2 0.0 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 Aconitase PF00330.20 ABK71814.1 - 1.1e-77 262.1 0.4 1.6e-75 254.9 0.4 2.2 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) DUF521 PF04412.13 ABK71814.1 - 2.3e-06 26.6 0.0 3.2e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF521) DUF3673 PF12425.8 ABK71814.1 - 0.59 10.1 4.0 0.4 10.6 0.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3673) DAO PF01266.24 ABK71815.1 - 4e-10 39.8 0.1 3.3e-05 23.7 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ABK71815.1 - 4.4e-10 39.6 0.6 1.9e-09 37.6 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 ABK71815.1 - 6e-08 32.4 1.5 0.003 16.9 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 ABK71815.1 - 9.1e-08 31.6 3.4 0.00057 19.1 2.4 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 ABK71815.1 - 1.9e-07 30.8 0.1 4.1e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 ABK71815.1 - 5.8e-05 22.3 1.5 0.0064 15.6 1.4 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 ABK71815.1 - 0.00032 20.0 0.3 0.00067 19.0 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ABK71815.1 - 0.00084 18.7 0.1 0.021 14.1 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ABK71815.1 - 0.0009 18.5 0.2 0.0016 17.7 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 ABK71815.1 - 0.0063 17.0 0.2 0.086 13.4 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ABK71815.1 - 0.0075 15.0 0.2 0.014 14.2 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein KR PF08659.10 ABK71815.1 - 0.17 11.7 0.1 0.29 11.0 0.1 1.3 1 0 0 1 1 1 0 KR domain adh_short_C2 PF13561.6 ABK71816.1 - 4.3e-58 196.6 5.6 8.3e-58 195.7 5.6 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK71816.1 - 7.8e-52 175.6 2.1 1.6e-51 174.6 2.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK71816.1 - 6.2e-20 71.9 2.4 1.1e-17 64.5 2.4 2.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK71816.1 - 7.8e-10 38.6 0.3 2.7e-09 36.8 0.3 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ABK71816.1 - 0.00025 21.0 1.4 0.00034 20.6 1.4 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 ABK71816.1 - 0.00043 19.5 0.1 0.00065 18.9 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Glyco_trans_4_4 PF13579.6 ABK71816.1 - 0.02 15.3 0.4 1.5 9.2 0.1 2.3 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 ABK71816.1 - 0.03 14.3 0.0 4.2 7.3 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.11 ABK71816.1 - 0.053 13.2 0.0 0.16 11.6 0.0 1.7 2 0 0 2 2 2 0 Starch synthase catalytic domain adh_short PF00106.25 ABK71817.1 - 2.6e-49 167.4 0.1 3.4e-49 166.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK71817.1 - 2.3e-37 128.8 1.2 2.6e-37 128.6 1.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK71817.1 - 2.7e-14 53.5 0.2 4.2e-14 52.9 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK71817.1 - 3.4e-05 23.4 0.1 5e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PALP PF00291.25 ABK71817.1 - 0.00077 19.0 4.8 0.015 14.7 0.7 2.8 2 1 0 3 3 3 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 ABK71817.1 - 0.013 15.4 0.7 0.028 14.4 0.7 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF1776 PF08643.10 ABK71817.1 - 0.21 10.9 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Polyketide_cyc2 PF10604.9 ABK71818.1 - 1.7e-21 77.0 1.8 1.8e-21 76.9 1.8 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 ABK71818.1 - 1.4e-11 44.7 0.0 1.8e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 ABK71818.1 - 0.00044 20.5 0.0 0.00057 20.1 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein FR47 PF08445.10 ABK71818.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein AMP-binding PF00501.28 ABK71819.1 - 1e-68 231.9 0.0 6.1e-51 173.3 0.0 2.2 1 1 1 2 2 2 2 AMP-binding enzyme PP-binding PF00550.25 ABK71819.1 - 2e-11 44.1 0.0 4.3e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.24 ABK71819.1 - 9.8e-10 37.8 3.3 0.00032 20.3 0.2 4.9 6 0 0 6 6 6 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 ABK71819.1 - 7.1e-06 25.7 5.6 0.001 18.7 0.1 4.8 5 0 0 5 5 5 1 Hexapeptide repeat of succinyl-transferase AMP-binding_C PF13193.6 ABK71819.1 - 0.025 15.5 0.1 0.13 13.3 0.0 2.4 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Aldedh PF00171.22 ABK71820.1 - 4.6e-96 322.1 0.0 5.3e-96 321.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TetR_N PF00440.23 ABK71821.1 - 2.3e-08 33.7 0.1 5.5e-08 32.5 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 ABK71821.1 - 3.5e-05 24.0 3.2 3.5e-05 24.0 3.2 2.0 2 1 1 3 3 3 1 BetI-type transcriptional repressor, C-terminal MerR_1 PF13411.6 ABK71821.1 - 0.0018 18.3 0.0 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 ABK71821.1 - 0.0075 16.0 0.0 0.022 14.5 0.0 1.9 1 1 0 1 1 1 1 MerR family regulatory protein HTH_24 PF13412.6 ABK71821.1 - 0.046 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma70_r4_2 PF08281.12 ABK71821.1 - 0.085 12.5 0.1 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 LRV PF01816.17 ABK71821.1 - 0.19 12.2 3.6 0.62 10.6 0.3 2.9 3 0 0 3 3 3 0 Leucine rich repeat variant ECH_1 PF00378.20 ABK71822.1 - 9.7e-54 182.3 0.0 1.1e-53 182.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK71822.1 - 3.3e-27 95.9 0.0 7.4e-27 94.7 0.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase LBP_M PF17385.2 ABK71822.1 - 0.16 11.5 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase central domain Phage_holin_4_2 PF04020.13 ABK71823.1 - 9.9e-31 106.5 19.4 1.2e-30 106.3 19.4 1.0 1 0 0 1 1 1 1 Mycobacterial 4 TMS phage holin, superfamily IV Ribosomal_S5 PF00333.20 ABK71824.1 - 1.4e-28 98.7 2.9 2.6e-28 97.8 2.9 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 ABK71824.1 - 2.1e-28 97.6 0.7 3.2e-28 97.0 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain adh_short PF00106.25 ABK71825.1 - 7.2e-26 90.9 0.0 7.2e-25 87.6 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK71825.1 - 1.7e-17 63.8 0.0 2.7e-17 63.1 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK71825.1 - 2.4e-07 30.8 0.1 3.7e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.15 ABK71825.1 - 0.089 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus DDE_Tnp_ISL3 PF01610.17 ABK71826.1 - 1.6e-64 217.9 0.0 2.1e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Transposase zf-ISL3 PF14690.6 ABK71826.1 - 1.1e-09 38.8 4.6 1.8e-09 38.1 2.5 2.5 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HTH_Tnp_ISL3 PF13542.6 ABK71826.1 - 2.4e-08 33.2 1.6 7e-08 31.8 1.6 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 Trypsin_2 PF13365.6 ABK71828.1 - 4.9e-34 118.4 3.4 1.2e-33 117.1 3.4 1.7 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 ABK71828.1 - 1.6e-15 57.5 0.7 3e-15 56.6 0.7 1.4 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 ABK71828.1 - 1e-12 48.2 1.5 3e-12 46.7 1.5 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 ABK71828.1 - 8.4e-06 25.5 0.9 2e-05 24.4 0.9 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 ABK71828.1 - 0.0019 18.5 1.6 0.0063 16.8 1.6 1.9 1 1 0 1 1 1 1 PDZ domain Peptidase_S46 PF10459.9 ABK71828.1 - 0.012 14.3 1.7 0.2 10.3 1.1 2.1 2 0 0 2 2 2 0 Peptidase S46 Mnd1 PF03962.15 ABK71828.1 - 0.21 11.9 0.0 0.42 10.9 0.0 1.4 1 0 0 1 1 1 0 Mnd1 HTH domain Peptidase_S7 PF00949.21 ABK71828.1 - 0.36 10.7 1.7 0.53 10.1 0.6 1.8 2 0 0 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease RraA-like PF03737.15 ABK71829.1 - 1.8e-43 148.3 2.5 2e-43 148.1 2.5 1.0 1 0 0 1 1 1 1 Aldolase/RraA FAA_hydrolase PF01557.18 ABK71830.1 - 4.5e-09 36.3 0.0 5.6e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF4185 PF13810.6 ABK71831.1 - 1.2e-108 363.1 5.4 1.5e-108 362.8 5.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) Glyco_hydro_43 PF04616.14 ABK71831.1 - 0.012 14.9 0.4 0.024 14.0 0.4 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 43 NLPC_P60 PF00877.19 ABK71832.1 - 5.9e-29 100.2 0.0 8.7e-29 99.6 0.0 1.3 1 0 0 1 1 1 1 NlpC/P60 family CHAP PF05257.16 ABK71832.1 - 0.065 13.8 0.1 0.13 12.9 0.1 1.5 1 0 0 1 1 1 0 CHAP domain DUF1175 PF06672.11 ABK71832.1 - 0.24 11.0 0.0 0.57 9.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1175) Histidinol_dh PF00815.20 ABK71833.1 - 1.3e-123 413.1 0.0 1.5e-123 412.8 0.0 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase Multi_Drug_Res PF00893.19 ABK71834.1 - 1.7e-22 79.9 7.5 2e-22 79.7 7.5 1.1 1 0 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 ABK71834.1 - 0.0081 16.3 11.1 0.0091 16.2 11.1 1.1 1 0 0 1 1 1 1 EamA-like transporter family CreD PF06123.12 ABK71834.1 - 0.0087 14.9 1.1 0.01 14.6 1.1 1.1 1 0 0 1 1 1 1 Inner membrane protein CreD TMEM234 PF10639.9 ABK71834.1 - 0.03 14.3 0.4 0.036 14.1 0.4 1.1 1 0 0 1 1 1 0 Putative transmembrane family 234 DUF543 PF04418.12 ABK71834.1 - 1.4 9.0 6.9 22 5.1 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF543) DUF4131 PF13567.6 ABK71834.1 - 3.4 7.3 14.9 2.6 7.6 2.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Aminotran_3 PF00202.21 ABK71835.1 - 2.8e-75 253.5 0.0 3.4e-75 253.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 ABK71835.1 - 9.6e-06 25.0 0.0 1.4e-05 24.5 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II MDMPI_N PF11716.8 ABK71836.1 - 3.1e-25 89.5 6.2 3.1e-25 89.5 6.2 1.4 2 0 0 2 2 2 1 Mycothiol maleylpyruvate isomerase N-terminal domain DinB_2 PF12867.7 ABK71836.1 - 0.00078 20.0 2.7 0.0013 19.2 2.1 1.8 1 1 0 1 1 1 1 DinB superfamily 3HCDH_N PF02737.18 ABK71837.1 - 4.3e-55 186.4 0.3 5.5e-55 186.0 0.3 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 ABK71837.1 - 1.3e-26 93.0 0.0 3.8e-26 91.5 0.0 1.8 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 ABK71837.1 - 0.0004 20.6 1.0 0.00077 19.7 1.0 1.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 ABK71837.1 - 0.0012 18.4 1.0 0.0023 17.6 0.4 1.7 1 1 1 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 ABK71837.1 - 0.0017 18.9 0.1 0.0039 17.7 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 ABK71837.1 - 0.053 12.9 0.1 0.091 12.1 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 ABK71837.1 - 0.06 13.6 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain TipAS PF07739.13 ABK71838.1 - 1e-32 113.1 1.3 9e-32 110.1 0.3 2.1 2 0 0 2 2 2 1 TipAS antibiotic-recognition domain MerR_1 PF13411.6 ABK71838.1 - 1.4e-15 57.1 0.1 2.4e-15 56.4 0.1 1.4 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 ABK71838.1 - 4.8e-14 51.8 0.8 8.8e-14 51.0 0.8 1.5 1 0 0 1 1 1 1 MerR family regulatory protein MerR-DNA-bind PF09278.11 ABK71838.1 - 3.4e-05 24.3 2.6 3.4e-05 24.3 2.6 2.2 3 0 0 3 3 3 1 MerR, DNA binding EF-hand_8 PF13833.6 ABK71838.1 - 0.096 12.6 0.1 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair DUF1488 PF07369.11 ABK71838.1 - 0.26 11.3 1.1 2 8.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) dTDP_sugar_isom PF00908.17 ABK71839.1 - 2.4e-53 180.3 0.0 2.7e-53 180.1 0.0 1.0 1 0 0 1 1 1 1 dTDP-4-dehydrorhamnose 3,5-epimerase HATPase_c PF02518.26 ABK71840.1 - 5e-08 33.4 1.7 1.8e-07 31.6 0.6 2.4 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 ABK71840.1 - 0.0003 20.7 0.1 0.00065 19.7 0.1 1.6 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 ABK71840.1 - 0.00043 20.1 0.1 0.00098 19.0 0.0 1.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA_3 PF07730.13 ABK71840.1 - 0.00059 20.3 0.4 0.0016 18.9 0.4 1.8 1 0 0 1 1 1 1 Histidine kinase TYW3 PF02676.14 ABK71840.1 - 0.015 14.7 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase TYW3 SLATT_fungal PF18142.1 ABK71840.1 - 0.06 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain ABC_membrane PF00664.23 ABK71841.1 - 4.9e-43 147.8 1.4 6.5e-43 147.3 1.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 ABK71841.1 - 1.3e-31 109.9 0.0 2.2e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane_3 PF13748.6 ABK71841.1 - 3.7e-08 32.9 4.2 1.1e-07 31.4 4.2 1.7 1 1 0 1 1 1 1 ABC transporter transmembrane region AAA PF00004.29 ABK71841.1 - 0.00022 21.7 0.0 0.0035 17.8 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ABK71841.1 - 0.00026 21.3 0.2 0.0052 17.1 0.1 2.7 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 ABK71841.1 - 0.00054 19.3 0.0 0.0015 17.9 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin SMC_N PF02463.19 ABK71841.1 - 0.0023 17.4 0.0 0.019 14.4 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ABK71841.1 - 0.0077 16.6 0.7 0.027 14.9 0.7 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 ABK71841.1 - 0.027 15.0 0.0 0.056 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 ABK71841.1 - 0.028 14.2 0.6 6.1 6.6 0.0 2.6 2 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system TsaE PF02367.17 ABK71841.1 - 0.028 14.4 0.1 0.058 13.4 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE APS_kinase PF01583.20 ABK71841.1 - 0.04 13.8 0.1 0.089 12.7 0.1 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_25 PF13481.6 ABK71841.1 - 0.045 13.3 1.5 0.21 11.1 1.5 2.2 1 1 0 1 1 1 0 AAA domain Holin_SPP1 PF04688.13 ABK71841.1 - 0.057 13.6 0.1 0.2 11.8 0.1 1.9 1 0 0 1 1 1 0 SPP1 phage holin AAA_5 PF07728.14 ABK71841.1 - 0.071 13.1 0.1 0.23 11.5 0.1 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 ABK71841.1 - 0.098 12.3 0.2 0.18 11.4 0.2 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF87 PF01935.17 ABK71841.1 - 0.098 12.7 0.3 0.18 11.9 0.3 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain ATP-synt_ab PF00006.25 ABK71841.1 - 0.12 12.0 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.6 ABK71841.1 - 0.16 11.6 2.0 0.47 10.1 2.0 1.8 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 ABK71841.1 - 0.17 11.0 0.0 0.32 10.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Amidohydro_2 PF04909.14 ABK71842.1 - 0.051 13.3 0.6 0.14 11.9 0.3 1.7 1 1 1 2 2 2 0 Amidohydrolase ABC_tran PF00005.27 ABK71843.1 - 6.7e-27 94.7 0.0 8.5e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK71843.1 - 6.2e-08 32.8 0.1 5.3e-05 23.2 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system BCA_ABC_TP_C PF12399.8 ABK71843.1 - 3.1e-06 27.0 0.2 5.3e-06 26.2 0.2 1.4 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_23 PF13476.6 ABK71843.1 - 5.6e-05 23.7 0.2 9.9e-05 22.9 0.2 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ABK71843.1 - 0.00021 21.2 0.0 0.00036 20.5 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 ABK71843.1 - 0.0033 16.9 0.5 0.008 15.6 0.1 1.7 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ABK71843.1 - 0.0049 16.6 0.1 0.013 15.2 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ABK71843.1 - 0.006 16.7 0.0 0.024 14.7 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 ABK71843.1 - 0.013 15.8 0.2 0.058 13.7 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ABK71843.1 - 0.019 14.7 0.3 0.24 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 ABK71843.1 - 0.021 14.5 0.0 0.028 14.1 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.6 ABK71843.1 - 0.024 15.0 0.2 0.041 14.3 0.2 1.5 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 ABK71843.1 - 0.072 12.6 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B DUF1428 PF07237.11 ABK71843.1 - 0.092 13.0 0.0 8.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1428) AAA_25 PF13481.6 ABK71843.1 - 0.13 11.9 0.9 2.3 7.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain DUF664 PF04978.12 ABK71844.1 - 7.8e-42 143.2 0.1 1.1e-41 142.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF664) DinB_2 PF12867.7 ABK71844.1 - 1.7e-10 41.5 0.9 3.1e-10 40.7 0.9 1.4 1 0 0 1 1 1 1 DinB superfamily DinB PF05163.12 ABK71844.1 - 1.3e-05 25.1 0.2 6.1e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 DinB family Arginase PF00491.21 ABK71845.1 - 1.7e-94 316.5 0.8 2.1e-94 316.2 0.8 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 ABK71845.1 - 0.083 13.1 0.2 0.13 12.5 0.2 1.3 1 0 0 1 1 1 0 UPF0489 domain Putative_PNPOx PF01243.20 ABK71846.1 - 8.2e-14 51.6 0.0 1e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FMN_bind_2 PF04299.12 ABK71846.1 - 0.04 13.6 0.0 0.094 12.4 0.0 1.5 2 0 0 2 2 2 0 Putative FMN-binding domain Pyrid_ox_like PF16242.5 ABK71846.1 - 0.086 12.4 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like NTP_transf_5 PF14907.6 ABK71847.1 - 0.055 13.1 0.0 0.067 12.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised nucleotidyltransferase Bac_luciferase PF00296.20 ABK71848.1 - 6.5e-52 176.9 0.0 7.4e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Y2_Tnp PF04986.13 ABK71848.1 - 0.035 14.2 0.0 0.056 13.5 0.0 1.2 1 0 0 1 1 1 0 Putative transposase Ribonuc_red_lgC PF02867.15 ABK71849.1 - 6.8e-147 490.2 1.3 3.9e-145 484.3 1.3 2.2 1 1 0 1 1 1 1 Ribonucleotide reductase, barrel domain RNR_N PF08343.10 ABK71849.1 - 1.1e-33 115.1 11.1 2.5e-33 114.0 9.4 2.3 2 0 0 2 2 2 1 Ribonucleotide reductase N-terminal Ribonuc_red_lgN PF00317.21 ABK71849.1 - 7.9e-13 48.2 0.1 3.7e-12 46.1 0.0 2.2 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain Fib_succ_major PF09603.10 ABK71849.1 - 0.039 14.6 0.0 0.076 13.6 0.0 1.6 1 0 0 1 1 1 0 Fibrobacter succinogenes major domain (Fib_succ_major) T4bSS_IcmS PF12608.8 ABK71849.1 - 0.1 12.9 0.2 0.26 11.6 0.2 1.6 1 0 0 1 1 1 0 Type IVb secretion, IcmS, effector-recruitment Unstab_antitox PF09720.10 ABK71851.1 - 0.017 15.2 0.1 0.025 14.6 0.1 1.2 1 0 0 1 1 1 0 Putative addiction module component Arabinose_Isome PF02610.15 ABK71852.1 - 9.3e-172 571.1 0.0 1.1e-171 570.9 0.0 1.0 1 0 0 1 1 1 1 L-arabinose isomerase Arabinose_Iso_C PF11762.8 ABK71852.1 - 1.2e-43 147.5 0.0 2.7e-43 146.4 0.0 1.6 1 0 0 1 1 1 1 L-arabinose isomerase C-terminal domain AMP-binding PF00501.28 ABK71854.1 - 1.7e-61 208.1 0.1 2.5e-61 207.6 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 ABK71854.1 - 3e-47 161.0 0.0 6.2e-47 159.9 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 ABK71854.1 - 1.2e-11 44.8 0.2 3.4e-11 43.3 0.2 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 ABK71854.1 - 1.2e-06 28.2 0.0 2.4e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 ABK71854.1 - 0.0001 23.2 0.2 0.00049 21.0 0.1 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 ABK71854.1 - 0.027 13.5 0.0 0.049 12.6 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PRK PF00485.18 ABK71855.1 - 7.5e-12 45.4 0.0 1.1e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 ABK71855.1 - 0.0035 17.9 0.0 0.0061 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain CoaE PF01121.20 ABK71855.1 - 0.037 13.7 0.0 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 Dephospho-CoA kinase UvrD-helicase PF00580.21 ABK71856.1 - 1.8e-46 159.2 0.0 9.4e-44 150.2 0.0 2.2 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 ABK71856.1 - 5.1e-39 133.9 0.1 8.5e-39 133.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain UvrD_C PF13361.6 ABK71856.1 - 1.2e-38 133.4 0.0 6.4e-19 68.5 0.0 2.1 1 1 1 2 2 2 2 UvrD-like helicase C-terminal domain HRDC PF00570.23 ABK71856.1 - 1.9e-20 72.6 0.0 4.3e-20 71.5 0.0 1.7 1 0 0 1 1 1 1 HRDC domain UvrD_C_2 PF13538.6 ABK71856.1 - 2.1e-09 37.1 0.3 3.4e-08 33.2 0.3 2.7 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 ABK71856.1 - 0.00024 20.9 9.7 0.0006 19.6 4.6 2.5 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 ABK71856.1 - 0.056 13.7 1.2 1.8 8.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain Helicase_Sgs1 PF11408.8 ABK71856.1 - 0.078 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Sgs1 RecQ helicase AAA_12 PF13087.6 ABK71856.1 - 0.084 12.5 0.0 2.9 7.5 0.1 2.8 2 1 0 2 2 2 0 AAA domain 2_5_RNA_ligase2 PF13563.6 ABK71858.1 - 5.5e-13 49.1 0.1 7.1e-13 48.7 0.1 1.0 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Pyr_redox_3 PF13738.6 ABK71859.1 - 1.9e-19 70.0 0.0 4.7e-17 62.2 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ABK71859.1 - 2.8e-15 56.3 0.0 7.4e-13 48.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ABK71859.1 - 8.1e-14 50.9 0.0 4.4e-11 41.9 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 ABK71859.1 - 1.5e-13 50.6 0.2 8.2e-11 41.6 0.0 3.4 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ABK71859.1 - 6.9e-13 48.6 0.1 5.4e-12 45.8 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ABK71859.1 - 9.1e-08 32.2 0.1 0.00027 21.0 0.0 3.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 ABK71859.1 - 1.4e-07 31.1 0.4 1.5e-05 24.4 0.2 2.3 1 1 1 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 ABK71859.1 - 9e-07 28.3 0.0 1.6e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 ABK71859.1 - 1.2e-06 28.1 0.1 1.6e-05 24.4 0.1 2.4 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 ABK71859.1 - 1.5e-06 28.6 0.3 0.0011 19.5 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ABK71859.1 - 4.8e-06 25.9 0.1 0.00045 19.4 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.24 ABK71859.1 - 6.7e-06 25.9 9.1 3.1e-05 23.7 1.3 3.3 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ABK71859.1 - 0.00013 21.5 0.2 0.0002 20.8 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ABK71859.1 - 0.00017 20.4 0.3 0.00029 19.7 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein Shikimate_DH PF01488.20 ABK71859.1 - 0.00026 21.1 0.0 0.3 11.2 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 ABK71859.1 - 0.00038 19.8 0.1 0.0025 17.2 0.0 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 ABK71859.1 - 0.0058 15.9 0.2 0.016 14.4 0.1 1.7 2 0 0 2 2 2 1 Thi4 family IlvN PF07991.12 ABK71859.1 - 0.0078 15.8 0.1 0.12 11.9 0.0 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Lycopene_cycl PF05834.12 ABK71859.1 - 0.015 14.4 0.1 0.17 10.9 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 ABK71859.1 - 0.017 15.5 0.0 3.3 8.2 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding ApbA PF02558.16 ABK71859.1 - 0.21 11.2 0.2 0.57 9.8 0.2 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 ABK71859.1 - 0.21 11.4 4.0 0.78 9.6 0.6 2.7 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amidase_3 PF01520.18 ABK71860.1 - 1.2e-33 116.7 0.0 1.5e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase AsnC_trans_reg PF01037.21 ABK71861.1 - 1.1e-13 51.0 0.0 2e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_AsnC-type PF13404.6 ABK71861.1 - 2e-12 46.7 3.1 4.3e-12 45.7 3.1 1.6 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 ABK71861.1 - 2.7e-10 39.6 0.0 4.1e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 ABK71861.1 - 3.6e-05 23.6 0.9 7e-05 22.6 0.9 1.5 1 0 0 1 1 1 1 MarR family HTH_28 PF13518.6 ABK71861.1 - 0.0044 17.1 0.9 0.0044 17.1 0.9 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain TrmB PF01978.19 ABK71861.1 - 0.0046 16.8 0.1 0.0091 15.9 0.1 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 ABK71861.1 - 0.013 15.2 0.8 0.024 14.4 0.8 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_47 PF16221.5 ABK71861.1 - 0.019 14.5 0.1 0.03 13.9 0.1 1.3 1 0 0 1 1 1 0 winged helix-turn-helix MarR PF01047.22 ABK71861.1 - 0.028 14.3 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_20 PF12840.7 ABK71861.1 - 0.048 13.7 1.9 0.051 13.6 0.5 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_10 PF04967.12 ABK71861.1 - 0.13 12.0 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 HTH DNA binding domain Peptidase_M20 PF01546.28 ABK71862.1 - 2.8e-07 30.4 1.1 4.1e-07 29.9 1.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ABK71862.1 - 9.5e-05 22.3 0.1 0.00031 20.6 0.1 1.8 1 1 0 1 1 1 1 Peptidase dimerisation domain DUF4267 PF14087.6 ABK71863.1 - 0.0088 16.1 3.4 0.017 15.2 3.4 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4267) DJ-1_PfpI PF01965.24 ABK71864.1 - 3.8e-22 78.9 0.1 4.5e-21 75.4 0.1 2.1 1 1 0 1 1 1 1 DJ-1/PfpI family HTH_18 PF12833.7 ABK71864.1 - 3.1e-21 75.4 0.8 5.4e-21 74.7 0.8 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 ABK71864.1 - 3.9e-13 49.1 0.0 1.7e-05 24.8 0.0 2.7 3 0 0 3 3 3 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_31 PF13560.6 ABK71864.1 - 0.012 15.9 2.5 1.1 9.6 0.2 3.2 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.6 ABK71864.1 - 0.073 13.2 0.2 3.8 7.7 0.0 3.1 2 1 1 3 3 3 0 Helix-turn-helix domain Cyt_bd_oxida_II PF02322.15 ABK71865.1 - 3.5e-58 197.4 35.7 4.2e-58 197.1 35.7 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II SecD_SecF PF02355.16 ABK71865.1 - 0.44 9.9 5.3 0.17 11.3 0.7 2.5 2 0 0 2 2 2 0 Protein export membrane protein CM_2 PF01817.21 ABK71866.1 - 1.8e-09 37.8 0.4 2.2e-09 37.5 0.4 1.1 1 0 0 1 1 1 1 Chorismate mutase type II SPATA1_C PF15743.5 ABK71866.1 - 0.17 11.9 0.2 0.2 11.7 0.2 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus BPD_transp_2 PF02653.16 ABK71867.1 - 1.5e-38 132.5 48.6 1.5e-38 132.5 48.6 1.4 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component DUF3989 PF13150.6 ABK71867.1 - 0.15 11.8 0.2 0.15 11.8 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3989) Bac_GDH PF05088.12 ABK71868.1 - 0 1339.2 0.0 0 1338.8 0.0 1.0 1 0 0 1 1 1 1 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog PF00208.21 ABK71868.1 - 5.6e-05 23.0 0.0 0.00019 21.3 0.0 1.8 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 ABK71868.1 - 0.0026 17.6 0.0 0.0081 16.0 0.0 1.8 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain MoaC PF01967.21 ABK71869.1 - 2.1e-52 176.8 0.9 2.3e-52 176.7 0.9 1.0 1 0 0 1 1 1 1 MoaC family Ribonuc_L-PSP PF01042.21 ABK71870.1 - 2e-30 105.3 0.0 2.2e-30 105.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP NIPSNAP PF07978.13 ABK71871.1 - 0.0019 18.4 0.0 0.0031 17.7 0.0 1.4 1 1 0 1 1 1 1 NIPSNAP Alpha-amylase PF00128.24 ABK71872.1 - 2.9e-18 66.5 0.0 4.1e-13 49.6 0.0 2.5 2 1 1 3 3 3 2 Alpha amylase, catalytic domain DUF3459 PF11941.8 ABK71872.1 - 3e-17 62.7 0.0 1.1e-16 61.0 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) Peptidase_S24 PF00717.23 ABK71873.1 - 3.4e-13 49.3 0.0 1.5e-08 34.5 0.0 2.7 2 0 0 2 2 2 2 Peptidase S24-like Peptidase_S26 PF10502.9 ABK71873.1 - 3.9e-05 23.5 0.1 0.00016 21.5 0.0 2.2 2 1 0 2 2 2 1 Signal peptidase, peptidase S26 PRiA4_ORF3 PF07929.11 ABK71874.1 - 2.1e-51 174.1 0.0 2.5e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein GCD14_N PF14801.6 ABK71876.1 - 0.1 12.5 1.3 0.32 10.9 0.0 2.3 2 1 1 3 3 3 0 tRNA methyltransferase complex GCD14 subunit N-term Cupin_2 PF07883.11 ABK71876.1 - 0.11 12.2 2.3 0.19 11.5 2.3 1.4 1 0 0 1 1 1 0 Cupin domain LAGLIDADG_WhiA PF14527.6 ABK71877.1 - 1.8e-25 88.8 0.0 3.8e-25 87.8 0.0 1.6 1 0 0 1 1 1 1 WhiA LAGLIDADG-like domain WhiA_N PF10298.9 ABK71877.1 - 5e-24 84.2 0.2 1.1e-23 83.1 0.2 1.6 1 0 0 1 1 1 1 WhiA N-terminal LAGLIDADG-like domain HTH_WhiA PF02650.14 ABK71877.1 - 2.8e-20 72.4 0.0 4.2e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 WhiA C-terminal HTH domain TerB PF05099.13 ABK71877.1 - 0.0076 16.2 1.6 0.016 15.2 1.6 1.6 1 0 0 1 1 1 1 Tellurite resistance protein TerB Peptidase_S11 PF00768.20 ABK71878.1 - 2e-35 122.4 0.0 2.8e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 ABK71878.1 - 9.5e-11 41.7 0.1 1.2e-10 41.4 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase enzyme family Transpeptidase PF00905.22 ABK71878.1 - 0.063 12.5 0.1 11 5.1 0.0 2.4 2 1 0 2 2 2 0 Penicillin binding protein transpeptidase domain IspD PF01128.19 ABK71879.1 - 2.8e-74 249.6 2.6 3.1e-74 249.4 2.6 1.0 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transf_3 PF12804.7 ABK71879.1 - 3.5e-12 47.0 6.4 5.8e-12 46.3 6.4 1.5 1 1 0 1 1 1 1 MobA-like NTP transferase domain CTP_transf_3 PF02348.19 ABK71879.1 - 2.3e-05 24.4 0.0 3.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transferase PF00483.23 ABK71879.1 - 0.037 13.6 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase AMP-binding PF00501.28 ABK71880.1 - 4.6e-87 292.3 0.1 5.6e-87 292.1 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK71880.1 - 3.4e-26 92.0 1.2 8.3e-26 90.8 1.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 ABK71880.1 - 3.5e-20 71.7 0.8 1.1e-19 70.0 0.3 2.1 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus SBP_bac_3 PF00497.20 ABK71881.1 - 9.4e-44 149.5 0.0 1.2e-43 149.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 BPD_transp_1 PF00528.22 ABK71881.1 - 8.4e-23 81.1 8.5 1.4e-22 80.3 8.5 1.4 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Lig_chan-Glu_bd PF10613.9 ABK71881.1 - 0.0078 16.4 0.0 0.04 14.1 0.0 1.9 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site PGK PF00162.19 ABK71882.1 - 7.3e-136 453.0 0.0 8.1e-136 452.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Glyoxalase PF00903.25 ABK71883.1 - 2e-15 57.1 1.9 9.2e-11 42.0 0.3 2.5 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ABK71883.1 - 0.0062 16.8 0.2 8.9 6.6 0.0 3.6 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 ABK71883.1 - 0.015 15.4 1.7 3.9 7.6 0.1 2.9 2 1 1 3 3 3 0 Glyoxalase-like domain GHMP_kinases_C PF08544.13 ABK71884.1 - 6.8e-09 36.0 0.5 1.8e-08 34.6 0.5 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 ABK71884.1 - 2.3e-08 34.2 2.5 2.3e-08 34.1 0.4 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain PKS_DE PF18369.1 ABK71884.1 - 0.6 10.7 5.5 8.9 7.0 0.1 3.4 2 2 0 2 2 2 0 Polyketide synthase dimerisation element domain DAO PF01266.24 ABK71885.1 - 3.7e-48 164.9 6.0 4.3e-48 164.7 6.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ABK71885.1 - 3.4e-05 23.1 5.2 0.00013 21.2 5.2 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ABK71885.1 - 0.00026 20.3 0.0 0.053 12.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ABK71885.1 - 0.00046 20.3 0.4 0.002 18.3 0.4 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ABK71885.1 - 0.00047 19.0 0.0 0.047 12.4 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Lycopene_cycl PF05834.12 ABK71885.1 - 0.00069 18.8 0.5 0.072 12.1 0.1 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Sacchrp_dh_NADP PF03435.18 ABK71885.1 - 0.0054 17.0 0.2 0.44 10.8 0.0 2.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Thi4 PF01946.17 ABK71885.1 - 0.0071 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 ABK71885.1 - 0.047 13.7 2.1 0.31 11.0 0.1 2.4 2 1 0 2 2 2 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 ABK71885.1 - 0.091 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FCD PF07729.12 ABK71886.1 - 1.5e-20 73.9 8.0 2.6e-20 73.1 8.0 1.4 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 ABK71886.1 - 1.3e-17 63.2 0.1 3.4e-17 61.8 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Rrf2 PF02082.20 ABK71886.1 - 3e-07 30.7 0.0 5.9e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator HTH_36 PF13730.6 ABK71886.1 - 3.4e-06 26.9 0.0 6.1e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 ABK71886.1 - 3.9e-06 26.7 0.2 9.4e-06 25.5 0.2 1.6 1 0 0 1 1 1 1 HTH domain HTH_24 PF13412.6 ABK71886.1 - 0.00011 21.7 0.0 0.00021 20.8 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 ABK71886.1 - 0.00013 21.9 0.1 0.00079 19.4 0.0 2.2 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 ABK71886.1 - 0.00037 20.3 0.1 0.001 18.9 0.1 1.8 1 0 0 1 1 1 1 MarR family HTH_41 PF14502.6 ABK71886.1 - 0.00059 19.5 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Fe_dep_repress PF01325.19 ABK71886.1 - 0.0017 18.5 0.0 0.0033 17.6 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain TrmB PF01978.19 ABK71886.1 - 0.0031 17.3 0.0 0.0059 16.5 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.7 ABK71886.1 - 0.0061 16.6 5.5 0.0091 16.0 0.1 3.1 4 0 0 4 4 4 1 Helix-turn-helix domain MarR PF01047.22 ABK71886.1 - 0.017 15.0 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_AsnC-type PF13404.6 ABK71886.1 - 0.02 14.7 0.3 0.052 13.4 0.3 1.8 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_29 PF13551.6 ABK71886.1 - 0.021 14.8 0.1 0.064 13.3 0.1 1.8 1 0 0 1 1 1 0 Winged helix-turn helix HTH_IclR PF09339.10 ABK71886.1 - 0.037 13.8 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_DeoR PF08220.12 ABK71886.1 - 0.045 13.5 0.1 0.092 12.5 0.1 1.4 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_23 PF13384.6 ABK71886.1 - 0.046 13.5 0.0 0.16 11.8 0.0 2.0 1 0 0 1 1 1 0 Homeodomain-like domain RepL PF05732.11 ABK71886.1 - 0.06 12.8 0.0 0.094 12.1 0.0 1.2 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) HTH_17 PF12728.7 ABK71886.1 - 0.073 13.3 0.1 0.16 12.2 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4423 PF14394.6 ABK71886.1 - 0.15 11.8 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) HTH_28 PF13518.6 ABK71886.1 - 0.31 11.2 2.4 0.34 11.1 0.2 2.2 2 0 0 2 2 1 0 Helix-turn-helix domain ABATE PF07336.11 ABK71886.1 - 8.9 7.0 18.9 1.1e+03 0.3 18.9 2.9 1 1 0 1 1 1 0 Putative stress-induced transcription regulator PAF-AH_p_II PF03403.13 ABK71887.1 - 1.8e-07 30.0 0.0 3.8e-05 22.4 0.0 2.7 2 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 ABK71887.1 - 0.00086 18.3 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme ABC_membrane_2 PF06472.15 ABK71890.1 - 5.2e-74 249.0 2.0 7e-74 248.6 2.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 SbmA_BacA PF05992.12 ABK71890.1 - 1.4e-24 87.1 5.0 3.8e-24 85.7 5.0 1.6 1 1 0 1 1 1 1 SbmA/BacA-like family ABC_tran PF00005.27 ABK71890.1 - 3.6e-17 63.1 0.0 7.9e-17 62.1 0.0 1.6 1 1 0 1 1 1 1 ABC transporter NACHT PF05729.12 ABK71890.1 - 4.4e-05 23.5 1.1 0.00038 20.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 ABK71890.1 - 5e-05 23.8 0.1 0.00014 22.3 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ABK71890.1 - 0.00028 21.2 0.0 0.00068 19.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ABK71890.1 - 0.00066 19.4 0.0 0.0017 18.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 ABK71890.1 - 0.00068 19.4 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ABK71890.1 - 0.0029 18.2 0.0 0.005 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 ABK71890.1 - 0.0047 17.2 0.3 0.01 16.1 0.3 1.6 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 ABK71890.1 - 0.0072 16.2 0.1 0.063 13.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 ABK71890.1 - 0.008 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 ABK71890.1 - 0.011 16.3 0.0 0.018 15.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 ABK71890.1 - 0.016 15.2 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 ABK71890.1 - 0.016 14.3 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.29 ABK71890.1 - 0.017 15.6 0.1 0.095 13.1 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 ABK71890.1 - 0.023 14.6 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 ABK71890.1 - 0.026 14.5 0.0 0.12 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 ABK71890.1 - 0.036 14.1 0.0 0.39 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ABK71890.1 - 0.036 13.6 0.0 0.088 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ABK71890.1 - 0.045 13.9 0.1 0.096 12.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 ABK71890.1 - 0.06 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 NTPase TsaE PF02367.17 ABK71890.1 - 0.085 12.9 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SMC_N PF02463.19 ABK71890.1 - 0.088 12.2 0.0 7.3 6.0 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 ABK71890.1 - 0.094 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 ABK71890.1 - 0.12 12.1 0.1 0.21 11.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 ABK71890.1 - 0.12 12.7 0.4 0.63 10.4 0.4 2.0 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ABK71890.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 ABK71890.1 - 0.19 10.9 0.0 0.34 10.1 0.0 1.4 1 1 0 1 1 1 0 NB-ARC domain AMP-binding PF00501.28 ABK71891.1 - 7.6e-100 334.5 0.1 9.9e-100 334.1 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK71891.1 - 2.6e-17 63.5 0.9 2.6e-17 63.5 0.9 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PfkB PF00294.24 ABK71892.1 - 1.9e-41 142.4 0.5 5e-41 141.0 0.5 1.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase p450 PF00067.22 ABK71893.1 - 8.3e-23 80.8 0.0 1.8e-19 69.8 0.0 3.1 2 1 0 2 2 2 2 Cytochrome P450 ABC_membrane PF00664.23 ABK71894.1 - 1.2e-39 136.6 6.0 1.5e-39 136.3 6.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 ABK71894.1 - 7.9e-33 113.9 0.0 1.3e-32 113.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ABK71894.1 - 0.0017 17.9 0.3 0.079 12.4 0.0 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ABK71894.1 - 0.0033 17.8 0.5 0.0075 16.7 0.5 1.6 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 ABK71894.1 - 0.054 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 ABK71894.1 - 0.061 12.9 1.8 0.27 10.8 1.8 2.1 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.17 ABK71894.1 - 0.079 13.0 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_22 PF13401.6 ABK71894.1 - 0.081 13.2 0.0 0.22 11.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ABK71894.1 - 0.093 12.5 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain BPD_transp_1 PF00528.22 ABK71895.1 - 1.7e-23 83.4 16.2 2.7e-23 82.7 16.2 1.4 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component UPF0016 PF01169.19 ABK71895.1 - 3.4 8.1 13.3 0.18 12.1 4.2 2.9 2 1 1 3 3 3 0 Uncharacterized protein family UPF0016 TrkA_N PF02254.18 ABK71896.1 - 5e-27 94.5 5.1 8.3e-27 93.8 5.1 1.3 1 0 0 1 1 1 1 TrkA-N domain Ion_trans_2 PF07885.16 ABK71896.1 - 2.4e-12 46.6 1.8 4.6e-12 45.7 1.8 1.5 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 ABK71896.1 - 0.0009 18.5 0.0 0.0013 18.0 0.0 1.1 1 0 0 1 1 1 1 Ion transport protein ADH_zinc_N PF00107.26 ABK71896.1 - 0.0087 16.0 1.7 1.5 8.8 0.0 2.4 1 1 1 2 2 2 2 Zinc-binding dehydrogenase BATS PF06968.13 ABK71896.1 - 0.014 15.5 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 Biotin and Thiamin Synthesis associated domain PK_C PF02887.16 ABK71896.1 - 0.031 14.5 1.6 0.031 14.5 1.6 2.2 1 1 1 2 2 2 0 Pyruvate kinase, alpha/beta domain Toprim_2 PF13155.6 ABK71896.1 - 0.077 13.4 0.3 0.19 12.1 0.3 1.7 1 0 0 1 1 1 0 Toprim-like NmrA PF05368.13 ABK71896.1 - 0.079 12.5 3.6 0.12 11.9 3.6 1.2 1 0 0 1 1 1 0 NmrA-like family TMEM169 PF15052.6 ABK71896.1 - 0.18 11.9 0.0 0.26 11.4 0.0 1.2 1 0 0 1 1 1 0 TMEM169 protein family FGE-sulfatase PF03781.16 ABK71897.1 - 3.2e-86 289.1 1.9 3.6e-86 289.0 1.9 1.0 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Amidohydro_3 PF07969.11 ABK71899.1 - 5.3e-84 283.4 11.4 6.3e-84 283.1 11.4 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 ABK71899.1 - 3.9e-18 65.9 2.3 1.1e-16 61.1 0.1 2.9 2 1 0 2 2 2 2 Amidohydrolase family UPRTase PF14681.6 ABK71900.1 - 5.7e-73 244.8 0.0 6.5e-73 244.6 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 ABK71900.1 - 2.7e-09 36.7 0.1 5.6e-09 35.7 0.1 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 ABK71900.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase NAD_binding_1 PF00175.21 ABK71901.1 - 3.6e-14 53.3 0.0 5.4e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DHODB_Fe-S_bind PF10418.9 ABK71901.1 - 2.7e-06 27.1 2.4 5.9e-06 26.0 2.4 1.5 1 0 0 1 1 1 1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B NAD_binding_6 PF08030.12 ABK71901.1 - 0.19 11.8 0.0 0.45 10.6 0.0 1.6 2 0 0 2 2 2 0 Ferric reductase NAD binding domain FAP PF07174.11 ABK71902.1 - 7e-142 472.2 81.3 3.1e-126 420.8 40.8 3.0 1 1 2 3 3 3 2 Fibronectin-attachment protein (FAP) Peripla_BP_4 PF13407.6 ABK71903.1 - 1.1e-33 116.9 0.4 1.4e-33 116.5 0.4 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 ABK71903.1 - 8.8e-14 51.6 0.1 1.2e-13 51.2 0.1 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family ATP_bind_3 PF01171.20 ABK71904.1 - 7.1e-28 97.6 0.0 9.8e-28 97.1 0.0 1.2 1 0 0 1 1 1 1 PP-loop family TilS PF09179.11 ABK71904.1 - 1.9e-10 41.1 0.9 7.5e-10 39.2 0.1 2.5 3 0 0 3 3 3 1 TilS substrate binding domain DUF3646 PF12362.8 ABK71904.1 - 0.028 14.7 0.1 5.9 7.2 0.0 2.4 2 0 0 2 2 2 0 DNA polymerase III gamma and tau subunits C terminal Asn_synthase PF00733.21 ABK71904.1 - 0.16 11.6 0.1 0.25 11.0 0.1 1.3 1 0 0 1 1 1 0 Asparagine synthase MMPL PF03176.15 ABK71905.1 - 2.8e-84 282.9 35.6 1.6e-42 145.7 14.1 2.4 2 0 0 2 2 2 2 MMPL family Sterol-sensing PF12349.8 ABK71905.1 - 0.048 13.5 27.2 0.91 9.3 9.7 2.6 2 1 0 2 2 2 0 Sterol-sensing domain of SREBP cleavage-activation Guanylate_cyc PF00211.20 ABK71907.1 - 1.7e-28 99.5 0.0 2.6e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HAMP PF00672.25 ABK71907.1 - 4.2e-16 59.1 0.2 1.4e-15 57.4 0.2 2.0 1 0 0 1 1 1 1 HAMP domain dCache_1 PF02743.18 ABK71907.1 - 5.7e-15 55.8 0.2 1e-14 55.0 0.2 1.5 1 0 0 1 1 1 1 Cache domain TarH PF02203.15 ABK71907.1 - 0.11 12.4 4.0 0.31 11.0 4.0 1.8 1 1 0 1 1 1 0 Tar ligand binding domain homologue HNOBA PF07701.14 ABK71907.1 - 0.15 11.5 0.1 0.33 10.4 0.1 1.5 2 0 0 2 2 2 0 Heme NO binding associated 4HB_MCP_1 PF12729.7 ABK71907.1 - 0.19 11.2 0.2 3.9 7.0 0.1 2.4 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction Malate_synthase PF01274.22 ABK71908.1 - 1.7e-186 620.6 0.0 2e-186 620.3 0.0 1.0 1 0 0 1 1 1 1 Malate synthase DivIC PF04977.15 ABK71908.1 - 0.16 11.8 0.1 0.33 10.7 0.1 1.5 1 0 0 1 1 1 0 Septum formation initiator Abhydrolase_1 PF00561.20 ABK71909.1 - 1.2e-19 71.0 0.2 2.5e-17 63.4 0.2 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ABK71909.1 - 6.1e-17 61.7 0.9 9.6e-17 61.0 0.9 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ABK71909.1 - 5e-16 60.0 9.8 5e-16 60.0 9.8 2.0 1 1 0 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 ABK71909.1 - 7.7e-08 31.6 0.0 1.7e-07 30.4 0.0 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme Ser_hydrolase PF06821.13 ABK71909.1 - 1.4e-06 28.2 0.6 0.0048 16.8 0.1 2.3 2 0 0 2 2 2 2 Serine hydrolase Chlorophyllase PF07224.11 ABK71909.1 - 2.1e-05 23.7 0.3 5.5e-05 22.3 0.3 1.6 1 1 0 1 1 1 1 Chlorophyllase PAF-AH_p_II PF03403.13 ABK71909.1 - 0.00092 17.8 0.6 0.61 8.5 0.0 2.3 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Esterase PF00756.20 ABK71909.1 - 0.0039 16.9 0.1 0.0075 15.9 0.1 1.4 1 0 0 1 1 1 1 Putative esterase DUF1057 PF06342.12 ABK71909.1 - 0.005 15.9 0.0 0.0058 15.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_5 PF12695.7 ABK71909.1 - 0.0073 16.1 0.0 0.33 10.7 0.1 2.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ABK71909.1 - 0.047 13.2 0.4 1.1 8.7 0.0 2.5 3 0 0 3 3 3 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 ABK71909.1 - 0.066 13.0 0.5 9.6 5.9 0.0 3.0 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Thioesterase PF00975.20 ABK71909.1 - 0.1 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DLH PF01738.18 ABK71909.1 - 0.12 11.9 0.0 8.2 5.9 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Nod_GRP PF07806.11 ABK71909.1 - 0.21 11.4 1.3 0.35 10.7 1.3 1.3 1 0 0 1 1 1 0 Nodule-specific GRP repeat MlaD PF02470.20 ABK71910.1 - 1.5e-12 47.6 0.0 2.8e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 MlaD protein Mce4_CUP1 PF11887.8 ABK71910.1 - 1.5e-10 41.0 1.7 2.3e-10 40.4 1.7 1.2 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative Baculo_PEP_C PF04513.12 ABK71910.1 - 0.0057 16.7 3.6 0.042 13.9 0.2 2.2 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus CK2S PF15011.6 ABK71910.1 - 0.081 12.8 0.1 0.35 10.7 0.0 1.9 1 1 1 2 2 2 0 Casein Kinase 2 substrate FlgN PF05130.12 ABK71910.1 - 0.16 12.5 0.3 0.23 11.9 0.3 1.2 1 0 0 1 1 1 0 FlgN protein MbtH PF03621.13 ABK71911.1 - 1.4e-23 82.0 0.0 1.8e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 MbtH-like protein GntR PF00392.21 ABK71913.1 - 3e-17 62.0 2.2 1e-16 60.3 0.3 2.4 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family FCD PF07729.12 ABK71913.1 - 2.5e-15 57.0 9.8 3.6e-15 56.5 9.8 1.2 1 0 0 1 1 1 1 FCD domain HTH_24 PF13412.6 ABK71913.1 - 0.0019 17.7 0.1 0.0042 16.6 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding PaaX PF07848.12 ABK71913.1 - 0.011 16.0 0.3 0.032 14.4 0.1 1.8 2 0 0 2 2 2 0 PaaX-like protein HTH_11 PF08279.12 ABK71913.1 - 0.019 14.9 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 HTH domain Rrf2 PF02082.20 ABK71913.1 - 0.039 14.3 0.0 0.098 13.0 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator MLTR_LBD PF17765.1 ABK71914.1 - 5e-43 147.1 2.0 1.5e-42 145.6 0.0 2.0 2 0 0 2 2 2 1 MmyB-like transcription regulator ligand binding domain HTH_31 PF13560.6 ABK71914.1 - 1.9e-16 60.1 7.8 3.5e-16 59.3 7.8 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 ABK71914.1 - 1.8e-07 31.1 0.0 3.1e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 ABK71914.1 - 0.017 15.1 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_25 PF13413.6 ABK71914.1 - 0.061 13.2 0.8 0.17 11.8 0.8 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain AtuA PF07287.11 ABK71915.1 - 5.5e-132 439.7 0.0 9e-132 439.0 0.0 1.3 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA AAA_33 PF13671.6 ABK71915.1 - 0.15 12.2 0.0 0.42 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain F420H2_quin_red PF04075.14 ABK71916.1 - 7.3e-40 136.1 0.0 8.8e-40 135.8 0.0 1.1 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase Putative_PNPOx PF01243.20 ABK71916.1 - 0.018 15.2 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Hexapep PF00132.24 ABK71917.1 - 1.3e-12 46.9 4.9 4.7e-05 22.9 0.1 3.9 3 1 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 ABK71917.1 - 4.4e-07 29.6 5.5 0.0023 17.7 0.1 3.2 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Rubella_E2 PF05749.11 ABK71917.1 - 0.048 13.1 1.2 0.16 11.4 0.1 2.0 1 1 1 2 2 2 0 Rubella membrane glycoprotein E2 DDE_Tnp_ISL3 PF01610.17 ABK71919.1 - 1.6e-64 217.9 0.0 2.1e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Transposase zf-ISL3 PF14690.6 ABK71919.1 - 1.1e-09 38.8 4.6 1.8e-09 38.1 2.5 2.5 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HTH_Tnp_ISL3 PF13542.6 ABK71919.1 - 2.4e-08 33.2 1.6 7e-08 31.8 1.6 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 Rhodanese PF00581.20 ABK71920.1 - 1.2e-06 29.0 0.0 2.1e-06 28.2 0.0 1.4 1 1 0 1 1 1 1 Rhodanese-like domain DUF442 PF04273.13 ABK71920.1 - 0.097 12.8 0.0 0.35 10.9 0.0 1.9 2 1 0 2 2 2 0 Putative phosphatase (DUF442) Pyr_redox_2 PF07992.14 ABK71921.1 - 4.2e-46 157.5 1.2 8.1e-46 156.6 0.8 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ABK71921.1 - 3.6e-21 75.5 0.0 1e-20 74.1 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 ABK71921.1 - 3.1e-18 66.1 1.8 7.2e-13 48.9 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ABK71921.1 - 1.1e-11 44.5 0.1 1e-06 28.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ABK71921.1 - 1.6e-07 30.7 4.4 5.4e-05 22.4 0.3 2.7 3 0 0 3 3 3 2 Glucose inhibited division protein A HI0933_like PF03486.14 ABK71921.1 - 9e-07 27.9 3.3 0.0006 18.6 0.3 3.3 3 0 0 3 3 3 2 HI0933-like protein AlaDh_PNT_C PF01262.21 ABK71921.1 - 1.6e-06 27.6 2.9 0.032 13.5 0.2 2.7 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 ABK71921.1 - 1.9e-05 24.2 1.5 1.9e-05 24.2 1.5 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 ABK71921.1 - 0.0002 21.7 0.7 0.36 11.3 0.1 2.6 2 1 0 2 2 2 2 Putative NAD(P)-binding Thi4 PF01946.17 ABK71921.1 - 0.00091 18.5 0.3 0.0029 16.9 0.1 1.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 ABK71921.1 - 0.0012 18.0 1.5 0.0012 18.0 1.5 2.5 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 ABK71921.1 - 0.0013 18.4 18.3 0.0066 16.1 0.6 4.5 4 1 0 4 4 4 2 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 ABK71921.1 - 0.016 14.6 0.0 2.6 7.4 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 ABK71921.1 - 0.025 13.6 0.3 0.025 13.6 0.3 2.6 2 1 1 3 3 3 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 ABK71921.1 - 0.027 13.7 5.5 0.037 13.3 0.4 2.3 2 0 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.18 ABK71921.1 - 0.038 13.9 2.8 4.1 7.2 0.1 2.8 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 ABK71921.1 - 0.27 11.5 0.2 0.27 11.5 0.2 3.4 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Excalibur PF05901.11 ABK71922.1 - 6.1e-06 26.8 1.5 6.6e-06 26.6 1.5 1.2 1 0 0 1 1 1 1 Excalibur calcium-binding domain Phage_holin_4_2 PF04020.13 ABK71923.1 - 0.0014 19.3 15.2 0.0022 18.7 15.2 1.4 1 1 0 1 1 1 1 Mycobacterial 4 TMS phage holin, superfamily IV CbiA PF01656.23 ABK71924.1 - 9.2e-11 41.9 0.0 1.7e-10 41.0 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 ABK71924.1 - 9e-10 38.7 0.0 1.3e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 ABK71924.1 - 5.1e-07 29.4 0.0 2.2e-06 27.3 0.0 1.8 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ParA PF10609.9 ABK71924.1 - 0.00042 19.9 0.1 0.0007 19.1 0.1 1.3 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase ArsA_ATPase PF02374.15 ABK71924.1 - 0.0076 15.5 0.1 0.012 14.9 0.1 1.3 1 0 0 1 1 1 1 Anion-transporting ATPase VirC1 PF07015.11 ABK71924.1 - 0.19 11.0 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 VirC1 protein GreA_GreB PF01272.19 ABK71925.1 - 7.5e-11 41.8 0.0 1.4e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term GreA_GreB_N PF03449.15 ABK71925.1 - 0.013 15.7 2.7 1.6 9.0 2.7 2.3 1 1 0 1 1 1 0 Transcription elongation factor, N-terminal DUF167 PF02594.16 ABK71926.1 - 6.1e-21 74.3 0.1 7.1e-21 74.1 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 Ald_Xan_dh_C2 PF02738.18 ABK71926.1 - 0.021 13.3 0.0 0.022 13.2 0.0 1.0 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase NUDIX PF00293.28 ABK71927.1 - 1.1e-17 64.3 0.7 1.3e-17 64.1 0.7 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 ABK71927.1 - 2.3e-06 27.5 1.7 3.9e-06 26.8 1.7 1.3 1 1 0 1 1 1 1 NUDIX domain DUF4242 PF14026.6 ABK71927.1 - 0.011 15.8 0.2 0.023 14.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4242) Glyoxalase PF00903.25 ABK71928.1 - 1.9e-12 47.5 0.0 2.9e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 ABK71928.1 - 9.4e-05 22.3 0.0 0.0012 18.8 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase-like domain FGGY_N PF00370.21 ABK71929.1 - 2.8e-69 233.4 0.0 4.7e-69 232.7 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 ABK71929.1 - 2e-60 204.0 1.2 3.3e-60 203.2 1.2 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 ABK71929.1 - 0.044 13.3 0.0 1.3 8.4 0.0 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family TetR_C_11 PF16859.5 ABK71930.1 - 8.5e-24 84.1 0.3 8.5e-24 84.1 0.3 2.0 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK71930.1 - 2.8e-10 39.8 0.0 6.8e-10 38.6 0.0 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_7 PF14246.6 ABK71930.1 - 4.9e-06 26.6 0.8 1.3e-05 25.2 0.2 1.9 2 0 0 2 2 2 1 AefR-like transcriptional repressor, C-terminal domain HTH_23 PF13384.6 ABK71930.1 - 0.00039 20.1 0.1 0.00099 18.8 0.1 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.15 ABK71930.1 - 0.0035 17.4 0.0 0.0068 16.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_Tnp_1_2 PF13022.6 ABK71930.1 - 0.0055 16.9 0.0 0.0088 16.2 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of insertion element transposase KfrA_N PF11740.8 ABK71930.1 - 0.0084 16.8 0.1 0.71 10.6 0.1 2.3 2 0 0 2 2 2 1 Plasmid replication region DNA-binding N-term HTH_28 PF13518.6 ABK71930.1 - 0.013 15.6 0.1 0.013 15.6 0.1 2.3 3 0 0 3 3 2 0 Helix-turn-helix domain HTH_32 PF13565.6 ABK71930.1 - 0.029 15.0 0.5 0.029 15.0 0.5 2.1 2 0 0 2 2 2 0 Homeodomain-like domain HTH_3 PF01381.22 ABK71930.1 - 0.03 14.4 0.0 0.066 13.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix TetR_C_16 PF17920.1 ABK71930.1 - 0.036 14.3 0.3 0.036 14.3 0.3 1.7 2 0 0 2 2 1 0 Tetracyclin repressor-like, C-terminal domain HTH_29 PF13551.6 ABK71930.1 - 0.037 14.0 0.0 0.037 14.0 0.0 2.2 2 0 0 2 2 1 0 Winged helix-turn helix LacI PF00356.21 ABK71930.1 - 0.043 13.6 0.0 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_11 PF08279.12 ABK71930.1 - 0.044 13.7 0.0 0.14 12.1 0.0 1.9 1 0 0 1 1 1 0 HTH domain MarR_2 PF12802.7 ABK71930.1 - 0.047 13.6 2.6 0.18 11.7 0.1 3.0 3 0 0 3 3 3 0 MarR family Pro_racemase PF05544.11 ABK71930.1 - 0.17 10.9 0.0 0.92 8.5 0.0 1.9 2 0 0 2 2 2 0 Proline racemase RES PF08808.11 ABK71931.1 - 4.8e-12 46.1 5.6 5.8e-12 45.8 5.6 1.1 1 0 0 1 1 1 1 RES domain adh_short PF00106.25 ABK71932.1 - 3.7e-49 166.9 0.5 4.4e-49 166.6 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK71932.1 - 5.3e-49 166.9 4.2 6.6e-48 163.3 4.2 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK71932.1 - 9.2e-13 48.5 0.8 1.4e-12 47.9 0.8 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK71932.1 - 0.0024 17.4 0.7 0.0066 15.9 0.7 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PCMT PF01135.19 ABK71932.1 - 0.13 12.0 0.2 0.19 11.4 0.2 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Metallophos_C PF14008.6 ABK71933.1 - 0.15 13.0 0.0 6.4 7.7 0.0 2.5 2 0 0 2 2 2 0 Iron/zinc purple acid phosphatase-like protein C EamA PF00892.20 ABK71934.1 - 1.7e-21 76.8 42.1 7.9e-11 42.3 16.8 2.1 2 0 0 2 2 2 2 EamA-like transporter family TMEM234 PF10639.9 ABK71934.1 - 3.3e-05 23.9 11.9 0.00016 21.6 4.9 3.0 2 1 0 2 2 2 2 Putative transmembrane family 234 TPT PF03151.16 ABK71934.1 - 2.9 7.2 12.5 6.6 6.0 12.2 1.7 1 1 0 1 1 1 0 Triose-phosphate Transporter family DUF899 PF05988.12 ABK71935.1 - 5.6e-89 297.3 0.0 6.5e-89 297.1 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) NfeD PF01957.18 ABK71936.1 - 9.3e-19 67.6 0.1 1.3e-18 67.1 0.1 1.2 1 0 0 1 1 1 1 NfeD-like C-terminal, partner-binding Phage_holin_3_6 PF07332.11 ABK71936.1 - 0.67 10.0 8.1 0.92 9.6 8.1 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DAO PF01266.24 ABK71937.1 - 1.9e-52 179.0 7.9 2.1e-52 178.8 7.9 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ABK71937.1 - 0.00033 20.0 3.6 0.00053 19.3 3.6 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 ABK71937.1 - 0.0004 19.6 4.8 0.00074 18.7 4.8 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 ABK71937.1 - 0.0012 18.3 1.4 0.0017 17.8 1.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ABK71937.1 - 0.0015 17.3 1.8 0.56 8.8 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein ThiF PF00899.21 ABK71937.1 - 0.0022 17.4 1.0 0.0039 16.6 1.0 1.3 1 0 0 1 1 1 1 ThiF family Trp_halogenase PF04820.14 ABK71937.1 - 0.006 15.5 0.1 0.0081 15.1 0.1 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 ABK71937.1 - 0.0078 15.5 0.7 0.014 14.7 0.7 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 ABK71937.1 - 0.024 15.1 0.1 0.066 13.7 0.1 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_8 PF13450.6 ABK71937.1 - 0.042 14.1 7.5 0.043 14.0 2.5 2.9 2 2 1 3 3 3 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ABK71937.1 - 0.16 11.2 1.9 0.27 10.4 1.9 1.2 1 0 0 1 1 1 0 Thi4 family UDPG_MGDP_dh_N PF03721.14 ABK71937.1 - 0.23 11.0 1.1 0.55 9.8 1.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 ABK71937.1 - 0.71 10.5 2.4 1.3 9.7 2.4 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 ABK71937.1 - 0.9 9.4 2.5 1.5 8.6 2.5 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HpcH_HpaI PF03328.14 ABK71938.1 - 3.7e-30 104.7 0.5 2.2e-28 98.9 0.5 2.3 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 ABK71938.1 - 1.7e-08 34.0 0.0 2.1e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 C-C_Bond_Lyase of the TIM-Barrel fold FliH PF02108.16 ABK71938.1 - 0.043 13.9 0.0 7.8 6.6 0.0 2.2 2 0 0 2 2 2 0 Flagellar assembly protein FliH Bac_luciferase PF00296.20 ABK71939.1 - 2.1e-51 175.2 4.0 2.6e-51 174.9 4.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase PEP_mutase PF13714.6 ABK71939.1 - 0.082 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase Gln-synt_C PF00120.24 ABK71940.1 - 3.9e-85 285.9 0.0 4.6e-85 285.7 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 ABK71940.1 - 0.11 12.4 0.1 0.38 10.6 0.0 1.9 2 0 0 2 2 2 0 Glutamine synthetase N-terminal domain DDE_Tnp_1_4 PF13701.6 ABK71941.1 - 1.7e-31 109.0 0.0 2.6e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain group 1 DDE_Tnp_1 PF01609.21 ABK71941.1 - 0.0043 16.7 0.0 0.053 13.1 0.0 2.1 1 1 0 1 1 1 1 Transposase DDE domain ParBc PF02195.18 ABK71941.1 - 0.036 14.4 0.0 0.089 13.1 0.0 1.7 1 1 0 1 1 1 0 ParB-like nuclease domain Carboxyl_trans PF01039.22 ABK71942.1 - 2.7e-87 293.5 0.1 3.5e-87 293.1 0.1 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain ECH_1 PF00378.20 ABK71942.1 - 0.0004 19.8 0.1 0.00081 18.8 0.1 1.5 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ACCA PF03255.14 ABK71942.1 - 0.18 11.7 1.5 4.9 7.0 0.0 3.0 3 1 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF4012 PF13196.6 ABK71943.1 - 0.039 14.4 0.7 0.097 13.1 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4012) DUF885 PF05960.11 ABK71943.1 - 1.2 8.7 23.2 2.4 7.7 23.2 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF885) GMC_oxred_N PF00732.19 ABK71944.1 - 3.2e-61 207.3 0.0 8.8e-53 179.6 0.0 2.1 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 ABK71944.1 - 5.9e-38 130.6 0.0 1e-37 129.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ABK71944.1 - 2e-06 27.2 0.7 0.013 14.6 0.2 2.9 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 ABK71944.1 - 1e-05 25.3 4.1 0.00016 21.4 3.5 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ABK71944.1 - 6.7e-05 23.0 0.4 0.0007 19.8 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ABK71944.1 - 0.00012 21.4 0.1 0.00027 20.2 0.1 1.6 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 ABK71944.1 - 0.00086 18.8 0.7 0.12 11.7 0.3 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ABK71944.1 - 0.0042 16.4 0.0 0.044 13.0 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ABK71944.1 - 0.0042 16.2 0.2 0.007 15.5 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 ABK71944.1 - 0.008 14.9 0.1 0.05 12.3 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.14 ABK71944.1 - 0.043 12.7 0.0 0.066 12.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 ABK71944.1 - 0.05 13.6 1.2 0.13 12.3 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.18 ABK71944.1 - 0.054 13.8 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.19 ABK71944.1 - 0.087 12.0 0.1 0.35 10.1 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain p450 PF00067.22 ABK71945.1 - 9e-23 80.7 1.4 2.1e-20 72.9 1.5 2.9 1 1 0 1 1 1 1 Cytochrome P450 HSP70 PF00012.20 ABK71946.1 - 2.7e-22 78.7 0.0 4.2e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ABK71946.1 - 0.00014 20.8 0.0 0.00029 19.7 0.0 1.4 1 1 0 1 1 1 1 MreB/Mbl protein DUF3060 PF11259.8 ABK71947.1 - 9.8e-24 82.8 10.3 4.9e-23 80.6 3.5 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3060) Pox_A_type_inc PF04508.12 ABK71947.1 - 0.076 12.9 0.4 0.13 12.2 0.4 1.3 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat PKcGMP_CC PF16808.5 ABK71947.1 - 0.18 11.7 0.7 0.28 11.1 0.7 1.2 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase FixS PF03597.15 ABK71947.1 - 0.87 9.4 3.4 1.4 8.6 3.4 1.3 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type RsfS PF02410.15 ABK71948.1 - 5.9e-24 84.4 0.3 7.2e-24 84.1 0.3 1.1 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation Sod_Fe_C PF02777.18 ABK71950.1 - 5.9e-36 122.7 0.1 9.6e-36 122.0 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 ABK71950.1 - 5.8e-31 106.8 3.4 5.8e-31 106.8 3.4 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain RNA_pol_Rpb1_1 PF04997.12 ABK71951.1 - 2.3e-82 276.8 0.0 3.8e-82 276.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 ABK71951.1 - 6.7e-66 222.4 0.1 1.1e-65 221.7 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 ABK71951.1 - 9.3e-39 133.3 0.0 6.8e-36 124.0 0.0 2.6 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 ABK71951.1 - 6.1e-28 97.7 0.0 1.5e-27 96.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 ABK71951.1 - 7.6e-07 29.1 0.0 2.1e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 OmpH PF03938.14 ABK71951.1 - 1.8 8.9 8.0 5 7.5 5.3 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) ECH_1 PF00378.20 ABK71952.1 - 4.6e-53 180.1 0.9 5.6e-53 179.8 0.9 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK71952.1 - 1.7e-28 100.1 0.8 1.9e-28 99.9 0.8 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ABC_tran PF00005.27 ABK71953.1 - 3.3e-32 111.8 0.0 4.5e-32 111.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK71953.1 - 1.4e-10 41.5 0.0 3.9e-05 23.6 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK71953.1 - 2e-06 27.4 0.0 0.00021 20.8 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 ABK71953.1 - 0.00099 19.0 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 ABK71953.1 - 0.0025 17.5 0.0 0.0047 16.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 ABK71953.1 - 0.0028 18.0 0.1 0.0039 17.6 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 ABK71953.1 - 0.0084 16.6 0.0 0.013 16.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ABK71953.1 - 0.017 15.7 0.0 0.03 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 ABK71953.1 - 0.025 13.4 0.1 1.8 7.3 0.1 2.7 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_30 PF13604.6 ABK71953.1 - 0.032 13.9 0.1 0.1 12.3 0.0 1.8 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 ABK71953.1 - 0.033 14.5 0.0 0.082 13.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 ABK71953.1 - 0.039 13.9 0.0 0.052 13.5 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_25 PF13481.6 ABK71953.1 - 0.043 13.4 0.0 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 ABK71953.1 - 0.046 13.9 0.0 0.2 11.9 0.0 2.0 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 ABK71953.1 - 0.049 13.3 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ABK71953.1 - 0.067 13.4 0.3 0.16 12.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.17 ABK71953.1 - 0.074 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein APS_kinase PF01583.20 ABK71953.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase CobU PF02283.16 ABK71953.1 - 0.15 11.6 0.1 0.84 9.2 0.0 2.1 2 1 1 3 3 3 0 Cobinamide kinase / cobinamide phosphate guanyltransferase TsaE PF02367.17 ABK71953.1 - 0.2 11.7 0.0 0.33 11.0 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AMP-binding PF00501.28 ABK71954.1 - 3e-91 306.2 0.2 5e-91 305.4 0.2 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 ABK71954.1 - 3.5e-27 95.2 0.0 5.1e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.25 ABK71954.1 - 3.8e-24 84.8 2.1 3.4e-12 46.5 0.1 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 ABK71954.1 - 1.9e-06 28.7 0.1 7.4e-06 26.9 0.1 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PAPS_reduct PF01507.19 ABK71955.1 - 1.3e-11 44.9 0.0 2.1e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family tRNA_Me_trans PF03054.16 ABK71955.1 - 0.13 11.0 0.0 0.48 9.2 0.0 1.8 1 1 0 1 1 1 0 tRNA methyl transferase TAL_FSA PF00923.19 ABK71956.1 - 1.6e-79 267.3 0.0 1.8e-79 267.1 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Rubella_E2 PF05749.11 ABK71956.1 - 0.005 16.3 0.0 0.0083 15.6 0.0 1.2 1 0 0 1 1 1 1 Rubella membrane glycoprotein E2 Amidohydro_2 PF04909.14 ABK71957.1 - 1.2e-22 81.0 0.3 1.5e-22 80.7 0.3 1.2 1 0 0 1 1 1 1 Amidohydrolase KIF1B PF12423.8 ABK71957.1 - 0.089 13.2 0.0 10 6.7 0.0 2.7 2 0 0 2 2 2 0 Kinesin protein 1B Peptidase_M19 PF01244.21 ABK71957.1 - 0.26 10.4 0.0 0.37 9.9 0.0 1.1 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) Glutaredoxin PF00462.24 ABK71958.1 - 6.8e-16 58.2 0.0 8e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 ABK71958.1 - 0.002 18.5 0.0 0.0021 18.5 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N_3 PF13417.6 ABK71958.1 - 0.011 16.1 0.0 0.014 15.8 0.0 1.3 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ABK71958.1 - 0.013 15.8 0.0 0.017 15.4 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain SH3BGR PF04908.15 ABK71958.1 - 0.029 14.5 0.0 0.032 14.4 0.0 1.2 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein Thioredoxin_3 PF13192.6 ABK71958.1 - 0.087 12.9 0.1 0.13 12.4 0.1 1.3 1 1 0 1 1 1 0 Thioredoxin domain BPD_transp_1 PF00528.22 ABK71959.1 - 1.6e-22 80.2 15.9 1.6e-22 80.2 15.9 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Lactamase_B_2 PF12706.7 ABK71960.1 - 1.3e-13 50.9 0.1 3.2e-13 49.6 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ABK71960.1 - 0.00019 21.4 0.0 0.00028 20.8 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain UDG PF03167.19 ABK71961.1 - 6.6e-18 65.2 0.0 9.2e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Bac_luciferase PF00296.20 ABK71963.1 - 2.8e-60 204.4 8.3 3.6e-60 204.0 8.3 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Amidohydro_2 PF04909.14 ABK71963.1 - 0.04 13.7 3.3 1.3 8.8 0.1 2.9 3 0 0 3 3 3 0 Amidohydrolase T7SS_ESX_EspC PF10824.8 ABK71964.1 - 2.9e-21 75.8 8.3 3.4e-21 75.6 8.3 1.0 1 0 0 1 1 1 1 Excreted virulence factor EspC, type VII ESX diderm WXG100 PF06013.12 ABK71964.1 - 0.00023 21.3 0.6 0.048 13.9 0.1 2.1 2 0 0 2 2 2 2 Proteins of 100 residues with WXG DUF2767 PF10965.8 ABK71964.1 - 0.012 15.5 0.1 2.6 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2767) PE PF00934.20 ABK71964.1 - 0.075 13.4 4.8 0.39 11.1 4.8 1.9 1 1 0 1 1 1 0 PE family EspB_PE PF18625.1 ABK71964.1 - 0.37 11.3 7.0 2.6 8.6 1.0 2.2 2 0 0 2 2 2 0 ESX-1 secreted protein B PE domain Aldedh PF00171.22 ABK71965.1 - 4.3e-152 506.9 0.2 4.8e-152 506.7 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glycos_transf_1 PF00534.20 ABK71966.1 - 9.6e-25 87.1 0.0 8.6e-24 84.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ABK71966.1 - 1.2e-24 87.3 0.8 3.5e-24 85.7 0.8 1.9 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 ABK71966.1 - 9.5e-24 84.6 3.2 9.5e-24 84.6 3.2 2.5 2 2 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 ABK71966.1 - 2e-21 76.8 0.1 1.6e-20 73.9 0.1 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 ABK71966.1 - 3.4e-13 49.8 0.0 7e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_20 PF00982.21 ABK71966.1 - 0.0069 15.1 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 ABK71966.1 - 0.12 12.1 0.0 0.48 10.1 0.0 1.8 2 0 0 2 2 2 0 Starch synthase catalytic domain Aldedh PF00171.22 ABK71967.1 - 7.3e-169 562.1 1.4 8.6e-169 561.9 1.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DCD PF06559.11 ABK71968.1 - 2.3e-14 53.0 0.0 1.1e-07 31.0 0.0 2.1 1 1 1 2 2 2 2 2'-deoxycytidine 5'-triphosphate deaminase (DCD) dUTPase PF00692.19 ABK71968.1 - 3.1e-11 43.1 0.0 4.9e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 dUTPase ATP-grasp_2 PF08442.10 ABK71969.1 - 9.6e-70 234.3 0.3 1.4e-69 233.7 0.3 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 ABK71969.1 - 1.7e-12 47.4 2.1 3e-12 46.6 2.1 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 ABK71969.1 - 5.4e-08 32.6 1.1 4.5e-07 29.5 1.1 2.1 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 ABK71969.1 - 1.1e-07 31.6 0.3 9e-07 28.6 0.1 2.3 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.19 ABK71969.1 - 9.4e-06 25.5 0.1 2.9e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp PF02222.22 ABK71969.1 - 0.045 13.3 0.0 0.094 12.3 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain ABC2_membrane_3 PF12698.7 ABK71970.1 - 4.3e-28 98.4 2.7 1.8e-13 50.3 2.8 2.1 2 0 0 2 2 2 2 ABC-2 family transporter protein DUF3533 PF12051.8 ABK71970.1 - 6.3e-10 38.5 3.6 4.3e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3533) ABC2_membrane PF01061.24 ABK71970.1 - 4.8e-08 32.7 14.3 4.8e-08 32.7 14.3 2.0 2 0 0 2 2 2 1 ABC-2 type transporter NAD_binding_8 PF13450.6 ABK71971.1 - 1.2e-07 31.9 2.5 2e-07 31.1 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ABK71971.1 - 2.4e-07 30.2 0.5 4.1e-07 29.5 0.5 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 ABK71971.1 - 3e-05 23.6 4.0 4.4e-05 23.0 4.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ABK71971.1 - 9e-05 21.9 1.2 0.00016 21.0 1.2 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ABK71971.1 - 0.00012 21.8 0.3 0.0011 18.7 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ABK71971.1 - 0.00092 18.4 2.2 0.0014 17.7 2.2 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ABK71971.1 - 0.0011 17.8 1.0 0.0016 17.2 1.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 ABK71971.1 - 0.0036 16.6 0.1 0.0051 16.1 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ABK71971.1 - 0.016 14.3 0.5 0.022 13.9 0.5 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Amino_oxidase PF01593.24 ABK71971.1 - 0.066 12.5 0.2 1.1 8.4 0.0 2.6 4 0 0 4 4 4 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 ABK71971.1 - 0.071 12.3 0.5 0.099 11.9 0.5 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ABK71971.1 - 0.099 11.5 0.3 0.14 11.0 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase 3HCDH_N PF02737.18 ABK71971.1 - 0.22 11.4 1.0 0.38 10.6 1.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HisKA_3 PF07730.13 ABK71972.1 - 1.7e-17 63.6 5.8 5e-17 62.2 5.8 1.8 1 0 0 1 1 1 1 Histidine kinase HAMP PF00672.25 ABK71972.1 - 4.3e-10 39.8 1.0 4.3e-10 39.8 1.0 4.0 5 1 1 6 6 6 1 HAMP domain HATPase_c PF02518.26 ABK71972.1 - 1.5e-05 25.5 0.1 0.0043 17.5 0.1 2.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 ABK71972.1 - 0.04 13.9 0.3 0.14 12.1 0.0 2.0 2 1 0 2 2 2 0 Histidine kinase-like ATPase domain H-kinase_dim PF02895.14 ABK71972.1 - 0.25 11.7 2.8 1.6 9.1 0.3 3.2 4 0 0 4 4 4 0 Signal transducing histidine kinase, homodimeric domain DUF3040 PF11239.8 ABK71972.1 - 0.29 11.5 2.2 0.84 10.0 2.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Bac_luciferase PF00296.20 ABK71973.1 - 2.1e-48 165.4 0.0 3.1e-48 164.8 0.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase PEP_hydrolase PF09370.10 ABK71973.1 - 0.089 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like Acyl-CoA_dh_1 PF00441.24 ABK71976.1 - 1.4e-37 129.2 0.8 2e-37 128.7 0.8 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK71976.1 - 1.8e-19 69.7 0.0 3e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ABK71976.1 - 6.2e-18 65.5 0.1 3.2e-17 63.2 0.0 2.2 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ABK71976.1 - 1.2e-17 64.5 0.4 2.2e-17 63.6 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CsbD PF05532.12 ABK71980.1 - 1.9e-12 46.9 14.9 2.7e-12 46.4 14.9 1.3 1 0 0 1 1 1 1 CsbD-like DUF4407 PF14362.6 ABK71980.1 - 3.9 6.8 9.7 4.4 6.6 9.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Na_H_Exchanger PF00999.21 ABK71981.1 - 1.1e-32 113.3 39.1 1.3e-32 113.0 39.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family HEAT_EZ PF13513.6 ABK71981.1 - 0.016 15.7 1.6 0.42 11.2 0.4 3.3 2 0 0 2 2 2 0 HEAT-like repeat F420H2_quin_red PF04075.14 ABK71982.1 - 1.1e-07 32.0 0.0 1.2e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase HTH_Tnp_Mu_1 PF02316.16 ABK71982.1 - 0.024 14.8 0.0 0.033 14.4 0.0 1.2 1 0 0 1 1 1 0 Mu DNA-binding domain TetR_C_31 PF17940.1 ABK71983.1 - 3.5e-08 33.6 2.6 3.5e-08 33.6 2.6 2.3 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK71983.1 - 1.5e-05 24.6 0.0 2.6e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 ABK71983.1 - 1.7e-05 25.0 2.6 1.7e-05 25.0 2.6 2.2 2 1 1 3 3 3 1 BetI-type transcriptional repressor, C-terminal TetR_C_30 PF17939.1 ABK71983.1 - 0.035 14.3 0.4 0.071 13.3 0.4 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Fer4_15 PF13459.6 ABK71984.1 - 1.4e-13 51.4 2.3 1.5e-13 51.3 2.3 1.0 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_13 PF13370.6 ABK71984.1 - 3e-10 40.5 0.2 3.3e-10 40.3 0.2 1.0 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_19 PF06902.11 ABK71984.1 - 2.8e-08 33.7 0.0 3.1e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Divergent 4Fe-4S mono-cluster Fer4_6 PF12837.7 ABK71984.1 - 0.0093 16.0 1.9 0.028 14.5 0.5 2.1 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_2 PF12797.7 ABK71984.1 - 0.084 13.0 0.8 0.2 11.8 0.1 1.9 2 0 0 2 2 2 0 4Fe-4S binding domain SAF PF08666.12 ABK71985.1 - 1.5e-11 44.7 0.6 1.5e-11 44.7 0.6 2.3 3 0 0 3 3 3 1 SAF domain ChapFlgA PF13144.6 ABK71985.1 - 8.4e-07 29.1 0.1 2.3e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 Chaperone for flagella basal body P-ring formation RcpC PF16976.5 ABK71985.1 - 0.00035 20.6 4.1 0.0035 17.4 1.7 2.6 2 0 0 2 2 2 1 Flp pilus assembly protein RcpC/CpaB Maf PF02545.14 ABK71985.1 - 0.062 13.2 0.1 0.087 12.7 0.1 1.2 1 0 0 1 1 1 0 Maf-like protein PQQ_2 PF13360.6 ABK71986.1 - 7.8e-05 22.4 1.3 0.0012 18.5 0.3 2.4 2 1 0 2 2 2 1 PQQ-like domain PQQ_3 PF13570.6 ABK71986.1 - 0.0031 18.0 0.1 0.0031 18.0 0.1 3.4 4 0 0 4 4 4 1 PQQ-like domain PQQ PF01011.21 ABK71986.1 - 0.021 14.7 0.7 3.7 7.6 0.0 3.7 3 0 0 3 3 3 0 PQQ enzyme repeat IclR PF01614.18 ABK71987.1 - 1.9e-20 73.0 0.0 3e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 ABK71987.1 - 2.3e-15 56.1 1.2 6.1e-15 54.8 1.2 1.8 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 ABK71987.1 - 2.6e-10 40.1 0.4 7.5e-10 38.6 0.4 1.8 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 ABK71987.1 - 8.8e-08 32.1 0.2 2.8e-07 30.5 0.2 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 ABK71987.1 - 9.7e-06 25.4 0.1 2e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR PF01047.22 ABK71987.1 - 1.1e-05 25.2 0.7 2.3e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 MarR family HTH_28 PF13518.6 ABK71987.1 - 9.4e-05 22.5 0.0 0.00022 21.3 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 ABK71987.1 - 0.00027 20.9 0.2 0.00059 19.8 0.2 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_24 PF13412.6 ABK71987.1 - 0.00037 20.0 0.2 0.00087 18.8 0.2 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding LexA_DNA_bind PF01726.16 ABK71987.1 - 0.00089 19.0 0.3 0.0027 17.4 0.0 1.9 2 0 0 2 2 2 1 LexA DNA binding domain TrmB PF01978.19 ABK71987.1 - 0.002 18.0 0.1 0.0081 16.0 0.0 1.9 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 ABK71987.1 - 0.002 18.0 0.3 0.0056 16.6 0.3 1.7 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_AsnC-type PF13404.6 ABK71987.1 - 0.0022 17.8 0.6 0.0051 16.6 0.6 1.7 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain Rrf2 PF02082.20 ABK71987.1 - 0.0032 17.8 0.1 0.0075 16.6 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulator Fe_dep_repress PF01325.19 ABK71987.1 - 0.0051 17.0 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_23 PF13384.6 ABK71987.1 - 0.012 15.4 0.5 0.033 14.0 0.0 2.0 2 0 0 2 2 1 0 Homeodomain-like domain HTH_11 PF08279.12 ABK71987.1 - 0.013 15.5 0.8 0.056 13.4 0.1 2.1 2 0 0 2 2 2 0 HTH domain DprA_WH PF17782.1 ABK71987.1 - 0.019 15.1 0.8 0.019 15.1 0.8 2.7 3 0 0 3 3 3 0 DprA winged helix domain HTH_38 PF13936.6 ABK71987.1 - 0.027 14.2 0.4 0.12 12.1 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 ABK71987.1 - 0.03 13.8 0.0 0.14 11.7 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_27 PF13463.6 ABK71987.1 - 0.035 14.6 0.0 0.1 13.1 0.0 1.8 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_47 PF16221.5 ABK71987.1 - 0.16 11.5 0.2 0.82 9.3 0.0 2.2 3 0 0 3 3 3 0 winged helix-turn-helix Urocanase_C PF17392.2 ABK71988.1 - 2.5e-91 304.5 0.6 4.6e-91 303.6 0.1 1.7 2 0 0 2 2 2 1 Urocanase C-terminal domain Urocanase PF01175.18 ABK71988.1 - 5.8e-84 281.0 0.0 7.6e-84 280.6 0.0 1.1 1 0 0 1 1 1 1 Urocanase Rossmann-like domain Urocanase_N PF17391.2 ABK71988.1 - 9.4e-60 199.9 0.0 2.1e-59 198.7 0.0 1.6 2 0 0 2 2 2 1 Urocanase N-terminal domain ABC_trans_N PF14510.6 ABK71988.1 - 0.09 13.4 0.0 0.3 11.7 0.0 1.9 1 0 0 1 1 1 0 ABC-transporter N-terminal DUF4131 PF13567.6 ABK71989.1 - 0.35 10.5 5.1 0.12 12.1 1.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Cyt_bd_oxida_II PF02322.15 ABK71989.1 - 1.1 8.5 5.9 2 7.7 5.9 1.4 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II MlaD PF02470.20 ABK71990.1 - 3.7e-16 59.2 0.2 6.2e-16 58.5 0.2 1.4 1 0 0 1 1 1 1 MlaD protein Mce4_CUP1 PF11887.8 ABK71990.1 - 0.0016 18.0 16.7 0.0063 16.0 5.1 1.5 1 1 1 2 2 2 2 Cholesterol uptake porter CUP1 of Mce4, putative YajC PF02699.15 ABK71990.1 - 0.0023 17.8 0.1 0.0042 16.9 0.1 1.4 1 0 0 1 1 1 1 Preprotein translocase subunit ATP-synt_B PF00430.18 ABK71990.1 - 0.0087 16.1 0.7 0.016 15.3 0.7 1.4 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) Flagellin_C PF00700.21 ABK71990.1 - 0.056 13.8 0.1 0.13 12.6 0.1 1.6 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region Bacillus_HBL PF05791.11 ABK71990.1 - 0.14 12.0 0.4 0.24 11.2 0.4 1.5 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Baculo_PEP_C PF04513.12 ABK71990.1 - 0.34 11.0 6.4 0.86 9.6 6.4 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Oxidored_FMN PF00724.20 ABK71991.1 - 4.9e-70 236.5 0.0 5.9e-70 236.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 ABK71991.1 - 0.0087 15.2 0.0 0.024 13.7 0.0 1.7 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) DUF4352 PF11611.8 ABK71992.1 - 1.6e-32 112.5 0.1 2.2e-32 112.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4352) DUF5067 PF16729.5 ABK71992.1 - 0.0011 18.9 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5067) DUF3426 PF11906.8 ABK71992.1 - 0.067 13.4 0.1 0.11 12.7 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3426) MTS PF05175.14 ABK71993.1 - 1.9e-18 66.6 0.0 1.3e-14 54.1 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase small domain PrmA PF06325.13 ABK71993.1 - 2e-15 57.0 0.0 2.8e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 ABK71993.1 - 6.1e-10 39.1 0.0 8.3e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABK71993.1 - 6.3e-10 39.6 0.0 1.1e-09 38.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 ABK71993.1 - 1.1e-08 35.0 0.7 4.6e-06 26.5 0.2 2.9 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 ABK71993.1 - 7.8e-08 32.2 0.0 1.2e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 ABK71993.1 - 4.2e-05 24.1 0.0 7.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABK71993.1 - 5.2e-05 23.1 0.0 0.00014 21.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 ABK71993.1 - 0.0012 18.6 0.0 0.0017 18.1 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_15 PF09445.10 ABK71993.1 - 0.0015 18.1 0.0 0.0081 15.8 0.0 1.9 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_16 PF10294.9 ABK71993.1 - 0.006 16.3 0.0 0.0093 15.7 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase N6_Mtase PF02384.16 ABK71993.1 - 0.039 13.2 0.0 0.36 10.0 0.0 2.1 1 1 0 1 1 1 0 N-6 DNA Methylase FtsJ PF01728.19 ABK71993.1 - 0.22 11.6 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Acyl-CoA_dh_1 PF00441.24 ABK71994.1 - 2.7e-28 99.1 0.6 4.3e-28 98.4 0.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK71994.1 - 6.2e-22 77.6 0.0 1.1e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ABK71994.1 - 1e-19 71.3 0.1 2.2e-19 70.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Multi_Drug_Res PF00893.19 ABK71995.1 - 6.5e-16 58.8 7.8 8.1e-16 58.5 7.8 1.1 1 0 0 1 1 1 1 Small Multidrug Resistance protein UTRA PF07702.13 ABK71998.1 - 4.9e-29 101.0 0.0 6.8e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 UTRA domain GntR PF00392.21 ABK71998.1 - 3.5e-15 55.4 0.1 8e-15 54.2 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Response_reg PF00072.24 ABK71999.1 - 1.8e-30 105.4 0.2 3e-30 104.7 0.2 1.4 1 0 0 1 1 1 1 Response regulator receiver domain ANTAR PF03861.14 ABK71999.1 - 5.7e-19 67.7 5.5 5.8e-19 67.7 2.1 2.4 2 0 0 2 2 2 1 ANTAR domain RE_XamI PF09572.10 ABK71999.1 - 0.038 13.7 0.3 0.053 13.2 0.3 1.3 1 0 0 1 1 1 0 XamI restriction endonuclease ABC_tran PF00005.27 ABK72000.1 - 6e-45 153.1 0.0 6.7e-26 91.4 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ABK72000.1 - 6.1e-11 42.7 0.2 0.012 15.5 0.0 3.2 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 ABK72000.1 - 7.4e-06 25.0 4.0 0.0026 16.6 0.1 3.1 2 1 0 2 2 2 2 Predicted ATPase of the ABC class SMC_N PF02463.19 ABK72000.1 - 7.1e-05 22.3 0.2 0.37 10.2 0.0 2.7 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ABK72000.1 - 0.002 18.4 2.1 0.29 11.4 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ABK72000.1 - 0.0027 17.4 0.2 0.011 15.4 0.1 2.2 2 0 0 2 2 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 ABK72000.1 - 0.0041 17.6 0.0 0.0084 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ABK72000.1 - 0.0045 16.7 0.7 1.1 8.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain HAMP PF00672.25 ABK72000.1 - 0.007 16.7 0.0 0.053 13.9 0.0 2.5 1 1 1 2 2 2 1 HAMP domain AAA_25 PF13481.6 ABK72000.1 - 0.016 14.8 0.7 0.63 9.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 ABK72000.1 - 0.021 14.5 0.1 0.095 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 ABK72000.1 - 0.031 14.2 0.2 0.17 11.7 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase SbcCD_C PF13558.6 ABK72000.1 - 0.056 13.7 1.4 13 6.1 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 ABK72000.1 - 0.058 13.9 0.0 7.5 7.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain DEAD PF00270.29 ABK72000.1 - 0.082 12.7 0.0 5.7 6.7 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase MMR_HSR1 PF01926.23 ABK72000.1 - 0.096 12.8 0.4 1.9 8.6 0.0 2.8 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_27 PF13514.6 ABK72000.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 ABK72000.1 - 0.24 10.7 4.5 3.5 6.9 0.3 2.8 3 0 0 3 3 3 0 KaiC AAA_10 PF12846.7 ABK72000.1 - 0.33 9.8 1.4 4.1 6.2 0.1 2.3 2 0 0 2 2 2 0 AAA-like domain DctM PF06808.12 ABK72001.1 - 7.8e-61 206.1 48.5 1.3e-60 205.4 48.5 1.3 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporter, DctM component Beta-lactamase PF00144.24 ABK72002.1 - 9.4e-63 212.4 4.8 1.2e-62 212.1 4.8 1.1 1 0 0 1 1 1 1 Beta-lactamase Acyltransferase PF01553.21 ABK72003.1 - 1e-15 57.5 0.0 1.8e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DAGAT PF03982.13 ABK72003.1 - 4.9e-08 32.3 0.0 6.1e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Fer2_3 PF13085.6 ABK72004.1 - 1.2e-31 109.0 0.0 2.6e-31 107.8 0.0 1.6 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.6 ABK72004.1 - 2.4e-11 43.9 2.9 4.4e-11 43.1 2.9 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 ABK72004.1 - 1.5e-10 41.0 4.4 2.5e-10 40.3 4.4 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 ABK72004.1 - 8.2e-06 26.3 2.9 1.6e-05 25.3 2.9 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 ABK72004.1 - 0.00067 19.8 7.1 0.00067 19.8 7.1 2.1 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 ABK72004.1 - 0.0025 18.4 11.6 0.016 15.8 10.7 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 ABK72004.1 - 0.0061 17.5 2.9 1.3 10.0 1.2 2.5 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_18 PF13746.6 ABK72004.1 - 0.0062 16.7 1.5 0.55 10.4 0.2 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4 PF00037.27 ABK72004.1 - 0.017 14.9 10.7 0.16 11.8 5.5 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_15 PF13459.6 ABK72004.1 - 0.031 15.0 3.9 0.81 10.5 0.3 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_4 PF12800.7 ABK72004.1 - 0.19 12.3 11.0 0.68 10.6 4.7 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_20 PF14691.6 ABK72004.1 - 0.25 11.1 9.6 0.78 9.5 0.4 2.5 1 1 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_6 PF12837.7 ABK72004.1 - 0.3 11.2 8.7 1.8 8.8 2.6 2.8 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_2 PF12797.7 ABK72004.1 - 0.79 10.0 17.3 0.56 10.4 7.6 2.8 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 ABK72004.1 - 1.4 10.0 14.8 3.5 8.8 0.3 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Lactamase_B_2 PF12706.7 ABK72005.1 - 1.5e-17 63.8 0.0 2e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ABK72005.1 - 1.1e-06 28.8 1.5 1.4e-06 28.4 1.5 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 ABK72005.1 - 0.048 13.5 0.0 0.098 12.5 0.0 1.5 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Zn-ribbon_8 PF09723.10 ABK72006.1 - 0.0033 17.5 1.8 0.059 13.5 0.1 2.2 2 0 0 2 2 2 1 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 ABK72006.1 - 0.0042 17.0 5.6 0.009 16.0 5.6 1.6 1 1 0 1 1 1 1 Transposase zinc-ribbon domain Lar_restr_allev PF14354.6 ABK72006.1 - 0.046 14.1 4.0 0.062 13.7 4.0 1.2 1 0 0 1 1 1 0 Restriction alleviation protein Lar HTH_Tnp_1 PF01527.20 ABK72007.1 - 4.9e-07 30.0 0.5 6.2e-07 29.6 0.5 1.2 1 0 0 1 1 1 1 Transposase MerR-DNA-bind PF09278.11 ABK72007.1 - 0.0012 19.4 0.1 0.0019 18.7 0.1 1.4 1 0 0 1 1 1 1 MerR, DNA binding HTH_28 PF13518.6 ABK72007.1 - 0.0024 18.0 0.1 0.0046 17.1 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain DUF1323 PF07037.11 ABK72007.1 - 0.0079 16.6 0.1 0.0093 16.3 0.1 1.1 1 0 0 1 1 1 1 Putative transcription regulator (DUF1323) TSC22 PF01166.18 ABK72007.1 - 0.0081 16.5 0.5 0.013 15.8 0.1 1.5 2 0 0 2 2 1 1 TSC-22/dip/bun family HMMR_N PF15905.5 ABK72007.1 - 0.013 15.0 0.3 0.018 14.5 0.3 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DivIC PF04977.15 ABK72007.1 - 0.029 14.1 0.5 0.35 10.7 0.3 2.1 2 0 0 2 2 2 0 Septum formation initiator YdaS_antitoxin PF15943.5 ABK72007.1 - 0.031 14.1 0.1 0.044 13.6 0.1 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_29 PF13551.6 ABK72007.1 - 0.051 13.6 0.2 0.099 12.7 0.2 1.6 1 1 1 2 2 2 0 Winged helix-turn helix HTH_23 PF13384.6 ABK72007.1 - 0.061 13.1 0.4 0.15 11.9 0.1 1.8 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 ABK72007.1 - 0.064 12.7 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Abhydrolase_3 PF07859.13 ABK72008.1 - 3.3e-54 183.9 0.2 4.3e-54 183.6 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ABK72008.1 - 0.00014 20.9 0.2 0.00014 20.9 0.2 1.5 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.21 ABK72008.1 - 0.032 13.7 0.1 0.23 10.9 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Resolvase PF00239.21 ABK72008.1 - 0.18 11.9 0.0 0.27 11.3 0.0 1.2 1 0 0 1 1 1 0 Resolvase, N terminal domain PBP PF01161.20 ABK72009.1 - 4.4e-36 124.1 0.0 5.2e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein ABC_tran PF00005.27 ABK72010.1 - 3.3e-28 98.9 0.0 4.9e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK72010.1 - 9.4e-11 42.1 0.3 3.1e-06 27.2 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK72010.1 - 0.0002 20.9 0.0 0.28 10.6 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ABK72010.1 - 0.00021 21.7 0.5 0.00036 21.0 0.5 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 ABK72010.1 - 0.00028 21.1 0.7 0.0031 17.7 0.7 2.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ABK72010.1 - 0.00069 19.9 0.2 0.0073 16.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ABK72010.1 - 0.00079 19.1 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 ABK72010.1 - 0.0046 17.1 0.1 0.035 14.3 0.1 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 ABK72010.1 - 0.0066 16.0 2.1 0.054 13.1 2.1 2.1 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 ABK72010.1 - 0.016 14.1 0.4 3 6.6 0.0 2.9 2 1 0 2 2 2 0 Predicted ATPase of the ABC class TniB PF05621.11 ABK72010.1 - 0.02 14.3 0.0 0.48 9.8 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein NACHT PF05729.12 ABK72010.1 - 0.027 14.4 0.4 0.68 9.8 0.1 2.2 2 0 0 2 2 2 0 NACHT domain RsgA_GTPase PF03193.16 ABK72010.1 - 0.034 14.1 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 ABK72010.1 - 0.3 11.6 0.1 0.41 11.1 0.1 1.1 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 ABK72011.1 - 1.3e-19 70.6 0.0 3.3e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 ABK72011.1 - 1.3e-11 45.1 0.5 1.3e-11 45.1 0.5 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 ABK72011.1 - 5.3e-08 33.2 0.0 1.3e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ABK72011.1 - 0.0017 18.4 0.0 0.0029 17.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1289 PF06945.13 ABK72011.1 - 0.076 12.8 0.3 0.27 11.1 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) Apolipoprotein PF01442.18 ABK72011.1 - 0.24 11.2 1.6 0.35 10.7 0.2 1.9 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Ank_5 PF13857.6 ABK72012.1 - 7.4e-16 58.0 0.0 1.7e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) zf-HC3 PF16827.5 ABK72012.1 - 0.083 13.1 0.3 0.17 12.1 0.3 1.4 1 0 0 1 1 1 0 zinc-finger Peripla_BP_6 PF13458.6 ABK72013.1 - 1.8e-48 166.0 10.7 2.3e-48 165.6 10.7 1.1 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 ABK72013.1 - 2.6e-17 63.0 0.0 3.2e-17 62.7 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_5 PF13433.6 ABK72013.1 - 6.4e-12 45.1 0.5 5.8e-08 32.1 0.1 2.1 2 0 0 2 2 2 2 Periplasmic binding protein domain Cons_hypoth698 PF03601.14 ABK72014.1 - 1.7e-50 171.6 20.9 2.4e-50 171.2 20.9 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 698 DNA_pol3_delta2 PF13177.6 ABK72015.1 - 9.8e-36 123.0 0.0 1.8e-35 122.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DNApol3-delta_C PF09115.10 ABK72015.1 - 8.4e-05 23.1 0.0 0.00015 22.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit, C terminal AAA PF00004.29 ABK72015.1 - 0.0001 22.8 0.0 0.00031 21.2 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ABK72015.1 - 0.00025 21.3 0.0 0.00092 19.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 ABK72015.1 - 0.077 13.0 0.0 0.46 10.5 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ApbA_C PF08546.11 ABK72015.1 - 0.26 11.5 1.5 6.7 6.9 0.1 2.6 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA C terminal Methyltransf_34 PF11312.8 ABK72015.1 - 0.42 9.8 1.0 0.66 9.2 1.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase AAA_16 PF13191.6 ABK72015.1 - 0.81 10.0 9.2 1.2 9.6 0.1 3.7 2 2 0 2 2 2 0 AAA ATPase domain DUF732 PF05305.14 ABK72016.1 - 0.043 14.2 1.9 0.047 14.1 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF732) PepSY_2 PF13670.6 ABK72016.1 - 0.33 11.0 2.8 0.39 10.8 2.8 1.1 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain PP_kinase_C_1 PF17941.1 ABK72018.1 - 1.2e-76 255.9 0.0 4.6e-76 254.0 0.0 1.8 2 0 0 2 2 2 1 Polyphosphate kinase C-terminal domain 1 PP_kinase PF02503.17 ABK72018.1 - 1.2e-73 247.0 0.0 2e-73 246.3 0.0 1.4 1 0 0 1 1 1 1 Polyphosphate kinase middle domain PP_kinase_C PF13090.6 ABK72018.1 - 1.8e-56 190.3 0.0 2.1e-55 186.8 0.0 2.3 2 0 0 2 2 2 1 Polyphosphate kinase C-terminal domain 2 PP_kinase_N PF13089.6 ABK72018.1 - 6e-37 126.3 0.0 1.4e-36 125.1 0.0 1.7 1 0 0 1 1 1 1 Polyphosphate kinase N-terminal domain PLDc_2 PF13091.6 ABK72018.1 - 9.6e-13 48.2 0.0 6.3e-05 22.9 0.0 2.9 2 1 0 2 2 2 2 PLD-like domain Aldedh PF00171.22 ABK72019.1 - 2.9e-143 477.7 1.4 3.4e-143 477.5 1.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.22 ABK72020.1 - 1.1e-180 601.1 0.4 1.4e-180 600.8 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 ABK72020.1 - 4.1e-08 32.7 0.0 6.3e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 ABK72020.1 - 0.037 13.5 0.0 0.09 12.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) His_Phos_1 PF00300.22 ABK72021.1 - 5.5e-46 156.7 0.7 6.1e-46 156.6 0.7 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DNA_pol3_alpha PF07733.12 ABK72022.1 - 1.2e-90 303.6 0.0 2.3e-90 302.7 0.0 1.5 2 0 0 2 2 2 1 Bacterial DNA polymerase III alpha NTPase domain DNA_pol3_finger PF17657.1 ABK72022.1 - 6.2e-60 201.3 0.0 9.1e-60 200.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha subunit finger domain PHP PF02811.19 ABK72022.1 - 2.3e-47 161.4 0.0 4.4e-47 160.5 0.0 1.5 1 0 0 1 1 1 1 PHP domain HHH_6 PF14579.6 ABK72022.1 - 1.9e-24 85.8 0.0 4.2e-24 84.6 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif tRNA_anti-codon PF01336.25 ABK72022.1 - 0.00061 19.7 0.0 0.0023 17.9 0.0 2.0 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain NUDIX PF00293.28 ABK72023.1 - 1.9e-16 60.3 0.1 6.9e-16 58.5 0.0 1.9 2 0 0 2 2 2 1 NUDIX domain Cas_Cas4 PF01930.17 ABK72023.1 - 0.28 11.3 0.0 0.44 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF83 FAD_binding_3 PF01494.19 ABK72024.1 - 1.5e-90 303.9 0.1 2.3e-90 303.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ABK72024.1 - 3e-06 27.1 4.6 0.022 14.4 0.2 2.9 1 1 2 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 ABK72024.1 - 3.2e-05 22.8 0.2 0.0013 17.5 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 ABK72024.1 - 5.5e-05 22.5 0.3 0.0043 16.3 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ABK72024.1 - 0.0001 21.3 0.1 0.091 11.6 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.27 ABK72024.1 - 0.0017 18.9 0.1 0.011 16.3 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ABK72024.1 - 0.0018 18.3 2.1 0.6 10.1 0.2 2.9 3 0 0 3 3 3 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 ABK72024.1 - 0.0022 17.1 1.2 0.26 10.3 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein TrkA_N PF02254.18 ABK72024.1 - 0.0045 17.2 0.1 0.0088 16.3 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_8 PF13450.6 ABK72024.1 - 0.0048 17.1 0.0 0.018 15.2 0.0 2.1 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 ABK72024.1 - 0.071 12.4 0.2 0.17 11.2 0.2 1.5 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 ABK72024.1 - 0.17 11.1 0.0 0.35 10.1 0.0 1.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF881 PF05949.12 ABK72025.1 - 6.6e-36 123.4 2.5 1.6e-35 122.1 0.4 2.0 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF881) DUF3450 PF11932.8 ABK72025.1 - 0.01 15.2 0.2 0.014 14.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Spc7 PF08317.11 ABK72025.1 - 0.023 13.6 0.4 0.031 13.2 0.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein ATG16 PF08614.11 ABK72025.1 - 0.04 14.1 1.9 0.087 13.0 1.9 1.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) HisG_C PF08029.11 ABK72025.1 - 0.15 12.2 0.7 1.5 9.0 0.1 2.7 3 0 0 3 3 3 0 HisG, C-terminal domain SlyX PF04102.12 ABK72025.1 - 0.18 12.4 0.3 0.18 12.4 0.3 1.7 2 0 0 2 2 2 0 SlyX AAA_3 PF07726.11 ABK72027.1 - 6.7e-65 216.8 0.1 1e-64 216.3 0.1 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 ABK72027.1 - 1.5e-20 72.8 0.1 4e-20 71.4 0.1 1.8 1 0 0 1 1 1 1 AAA lid domain AAA_5 PF07728.14 ABK72027.1 - 6.4e-15 55.4 0.0 1e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.23 ABK72027.1 - 3.1e-05 23.2 0.0 8.3e-05 21.8 0.0 1.7 1 1 0 1 1 1 1 MCM P-loop domain AAA PF00004.29 ABK72027.1 - 5.8e-05 23.5 0.0 0.00013 22.4 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 ABK72027.1 - 8.2e-05 22.4 0.0 0.0004 20.2 0.0 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 ABK72027.1 - 0.00014 21.6 0.0 0.0026 17.5 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 ABK72027.1 - 0.0011 18.4 0.7 0.0092 15.4 0.1 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 ABK72027.1 - 0.011 16.1 0.0 0.02 15.3 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain DUF3584 PF12128.8 ABK72027.1 - 0.3 8.6 0.1 0.39 8.2 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Proton_antipo_M PF00361.20 ABK72030.1 - 1.5e-63 214.8 20.9 1.5e-63 214.8 20.9 2.0 3 0 0 3 3 3 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 ABK72030.1 - 0.00014 21.8 0.5 0.00014 21.8 0.5 3.1 2 0 0 2 2 2 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus NADHdeh_related PF10125.9 ABK72030.1 - 0.00034 20.1 5.6 0.00034 20.1 5.6 2.7 3 0 0 3 3 3 1 NADH dehydrogenase I, subunit N related protein 5_3_exonuc_N PF02739.16 ABK72031.1 - 1.9e-47 161.1 0.0 2.7e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 ABK72031.1 - 6.9e-18 65.0 0.0 1.2e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold acVLRF1 PF18859.1 ABK72031.1 - 0.018 15.3 4.0 0.39 11.0 0.7 2.8 1 1 2 3 3 3 0 Actinobacteria/chloroflexi VLRF1 release factor HHH_5 PF14520.6 ABK72031.1 - 0.12 13.0 0.1 0.39 11.4 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix domain HHH_2 PF12826.7 ABK72031.1 - 0.14 12.3 0.0 0.37 10.9 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif adh_short PF00106.25 ABK72033.1 - 4.6e-25 88.2 0.1 1.1e-24 87.0 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK72033.1 - 3.9e-19 69.1 0.0 6.3e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ABK72033.1 - 0.042 13.3 0.0 0.068 12.6 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 ABK72034.1 - 7.6e-33 113.6 0.3 9.3e-33 113.3 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK72034.1 - 1.9e-31 109.4 0.0 2.6e-31 109.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK72034.1 - 4.5e-06 26.7 1.9 0.0038 17.1 1.8 2.4 2 1 0 2 2 2 2 KR domain TrkA_N PF02254.18 ABK72034.1 - 0.00025 21.3 0.8 0.0005 20.3 0.8 1.4 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.21 ABK72034.1 - 0.0003 20.4 0.1 0.0006 19.4 0.1 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 ABK72034.1 - 0.0013 18.1 1.6 0.0015 17.9 0.3 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 ABK72034.1 - 0.0035 17.3 0.4 0.007 16.3 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 ABK72034.1 - 0.0046 16.9 2.0 0.0076 16.2 2.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_7 PF13241.6 ABK72034.1 - 0.0097 16.3 0.1 0.018 15.5 0.1 1.6 2 0 0 2 2 2 1 Putative NAD(P)-binding PrpR_N PF06506.11 ABK72034.1 - 0.0099 15.5 0.3 0.017 14.7 0.3 1.3 1 0 0 1 1 1 1 Propionate catabolism activator 3Beta_HSD PF01073.19 ABK72034.1 - 0.015 14.3 0.0 0.02 13.9 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 ABK72034.1 - 0.02 15.5 0.5 0.036 14.6 0.5 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.13 ABK72034.1 - 0.031 13.8 0.8 0.048 13.2 0.8 1.2 1 0 0 1 1 1 0 NmrA-like family AlaDh_PNT_C PF01262.21 ABK72034.1 - 0.036 13.3 2.6 0.067 12.5 2.6 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CoA_binding PF02629.19 ABK72035.1 - 5.6e-25 87.9 5.8 5.7e-24 84.6 2.2 2.6 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 ABK72035.1 - 8e-16 58.2 0.8 2.1e-15 56.9 0.8 1.7 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 ABK72035.1 - 1.8e-12 47.2 0.1 3.1e-12 46.5 0.1 1.3 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 ABK72035.1 - 0.005 17.3 0.1 0.016 15.7 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain TetR_N PF00440.23 ABK72036.1 - 5.3e-18 64.5 1.6 5.3e-18 64.5 1.6 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_18 PF12833.7 ABK72036.1 - 0.003 17.8 1.9 0.02 15.1 0.5 2.6 3 1 0 3 3 3 1 Helix-turn-helix domain TetR_C_6 PF13977.6 ABK72036.1 - 0.003 17.8 2.3 0.1 12.9 0.5 2.4 1 1 1 2 2 2 1 BetI-type transcriptional repressor, C-terminal TetR_C_31 PF17940.1 ABK72036.1 - 0.039 14.1 4.8 0.097 12.9 1.8 2.6 1 1 2 3 3 3 0 Tetracyclin repressor-like, C-terminal domain PALP PF00291.25 ABK72037.1 - 2.1e-38 132.4 3.3 2.6e-38 132.1 3.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NAD_Gly3P_dh_N PF01210.23 ABK72037.1 - 0.071 13.1 0.2 0.16 12.0 0.2 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus MIP PF00230.20 ABK72038.1 - 4.7e-46 157.3 24.7 5.5e-46 157.1 24.7 1.0 1 0 0 1 1 1 1 Major intrinsic protein ADH_zinc_N PF00107.26 ABK72039.1 - 9.6e-14 51.5 0.5 2.1e-13 50.4 0.5 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ABK72039.1 - 8.6e-06 25.6 0.0 0.0014 18.5 0.0 2.5 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 ABK72039.1 - 3.7e-05 23.6 0.0 9.4e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 N-terminal domain of oxidoreductase adh_short PF00106.25 ABK72039.1 - 0.035 13.5 0.3 0.061 12.8 0.3 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Epimerase PF01370.21 ABK72039.1 - 0.098 12.1 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family YaeQ PF07152.12 ABK72040.1 - 1.6e-58 197.2 0.0 1.8e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 YaeQ protein COX15-CtaA PF02628.15 ABK72041.1 - 8e-16 58.0 39.4 1.4e-11 44.1 23.6 3.0 2 1 0 2 2 2 2 Cytochrome oxidase assembly protein Peptidase_M24 PF00557.24 ABK72042.1 - 5.2e-20 72.0 0.0 6.8e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 ABK72042.1 - 1.6e-09 38.5 0.0 3.6e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain HypD PF01924.16 ABK72043.1 - 5.5e-155 515.7 0.0 6.3e-155 515.6 0.0 1.0 1 0 0 1 1 1 1 Hydrogenase formation hypA family F_bP_aldolase PF01116.20 ABK72044.1 - 1.1e-79 267.8 0.1 1.3e-79 267.7 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Polysacc_synt_3 PF13440.6 ABK72045.1 - 4.6e-65 219.7 15.4 1e-64 218.6 15.4 1.6 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Polysacc_synt PF01943.17 ABK72045.1 - 6.9e-25 88.0 16.5 6.9e-25 88.0 16.5 2.1 3 1 0 3 3 3 1 Polysaccharide biosynthesis protein BPD_transp_1 PF00528.22 ABK72047.1 - 4e-13 49.5 19.6 4e-13 49.5 19.6 2.3 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component WYL PF13280.6 ABK72048.1 - 1e-34 120.1 0.1 1.6e-34 119.4 0.1 1.3 1 0 0 1 1 1 1 WYL domain HTH_11 PF08279.12 ABK72048.1 - 1.7e-15 56.7 0.1 2.8e-15 56.0 0.1 1.3 1 0 0 1 1 1 1 HTH domain HTH_DeoR PF08220.12 ABK72048.1 - 9.9e-06 25.2 0.0 1.9e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain Rrf2 PF02082.20 ABK72048.1 - 2.9e-05 24.3 0.2 7.7e-05 23.0 0.2 1.7 1 0 0 1 1 1 1 Transcriptional regulator Fe_dep_repress PF01325.19 ABK72048.1 - 0.0015 18.7 0.0 0.0033 17.6 0.0 1.5 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_29 PF13551.6 ABK72048.1 - 0.033 14.2 0.2 0.075 13.1 0.2 1.6 1 0 0 1 1 1 0 Winged helix-turn helix HTH_20 PF12840.7 ABK72048.1 - 0.035 14.2 0.4 0.14 12.2 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.7 ABK72048.1 - 0.052 13.4 0.3 0.15 12.0 0.3 1.8 1 0 0 1 1 1 0 MarR family HTH_23 PF13384.6 ABK72048.1 - 0.062 13.1 0.1 0.18 11.7 0.1 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Crp_2 PF13545.6 ABK72048.1 - 0.071 13.1 0.1 0.23 11.5 0.1 1.9 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_24 PF13412.6 ABK72048.1 - 0.086 12.4 0.2 0.15 11.7 0.2 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_36 PF13730.6 ABK72048.1 - 0.094 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Mga PF08280.11 ABK72048.1 - 0.25 11.4 0.0 0.39 10.8 0.0 1.2 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain adh_short_C2 PF13561.6 ABK72049.1 - 2.3e-63 213.9 6.4 3.3e-63 213.4 6.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK72049.1 - 2.2e-51 174.1 5.0 2.7e-51 173.8 5.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK72049.1 - 2.2e-08 34.2 3.5 3.3e-08 33.6 3.0 1.6 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 ABK72049.1 - 0.0039 16.2 0.3 0.0063 15.5 0.3 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 ABK72049.1 - 0.01 16.4 0.3 0.01 16.4 0.3 2.1 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 ABK72049.1 - 0.018 14.5 0.6 0.018 14.5 0.6 2.0 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 ABK72049.1 - 0.23 11.7 2.3 0.21 11.9 0.5 1.8 2 0 0 2 2 2 0 TrkA-N domain HMGL-like PF00682.19 ABK72050.1 - 3.3e-49 167.8 2.3 4.2e-49 167.5 2.3 1.1 1 0 0 1 1 1 1 HMGL-like DmpG_comm PF07836.11 ABK72050.1 - 5.5e-28 96.3 0.0 1.3e-27 95.1 0.0 1.7 1 0 0 1 1 1 1 DmpG-like communication domain MDMPI_N PF11716.8 ABK72051.1 - 1.9e-12 48.1 4.7 1.4e-11 45.2 2.1 2.4 1 1 1 2 2 2 1 Mycothiol maleylpyruvate isomerase N-terminal domain DinB PF05163.12 ABK72051.1 - 0.0017 18.3 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 DinB family DinB_2 PF12867.7 ABK72051.1 - 0.012 16.1 0.1 0.018 15.5 0.1 1.6 1 1 0 1 1 1 0 DinB superfamily Arr-ms PF12120.8 ABK72051.1 - 0.14 12.4 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Rifampin ADP-ribosyl transferase Amidase PF01425.21 ABK72052.1 - 1.1e-102 344.4 0.2 3.5e-102 342.7 0.2 1.7 1 1 0 1 1 1 1 Amidase polyprenyl_synt PF00348.17 ABK72053.1 - 4.2e-65 219.4 0.0 4.9e-65 219.1 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase ELFV_dehydrog PF00208.21 ABK72054.1 - 2.6e-87 292.6 0.9 3.3e-87 292.2 0.9 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 ABK72054.1 - 8.4e-50 168.0 0.0 2.5e-49 166.5 0.0 1.8 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain TetR_N PF00440.23 ABK72055.1 - 9.8e-13 47.7 0.1 2.2e-12 46.6 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 ABK72055.1 - 1.9e-05 24.9 0.8 4.4e-05 23.7 0.1 2.0 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain 3HCDH_RFF PF18321.1 ABK72055.1 - 0.062 13.8 0.2 0.24 11.8 0.0 2.0 2 0 0 2 2 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain TetR_C_25 PF17933.1 ABK72055.1 - 0.085 13.2 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain 4HBT PF03061.22 ABK72056.1 - 5e-13 49.2 0.0 8.1e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 ABK72056.1 - 8.8e-13 48.8 0.0 1.1e-12 48.5 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 ABK72056.1 - 2.6e-06 26.9 0.1 0.0023 17.3 0.1 2.1 2 0 0 2 2 2 2 Acyl-ACP thioesterase Abhydrolase_6 PF12697.7 ABK72057.1 - 1e-19 72.0 12.1 1.2e-19 71.8 12.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK72057.1 - 3.9e-14 52.5 0.0 1.2e-13 50.9 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ABK72057.1 - 7.6e-14 52.0 0.2 1.1e-13 51.4 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 ABK72057.1 - 0.00024 21.0 0.1 0.00036 20.4 0.1 1.3 1 0 0 1 1 1 1 Serine hydrolase Esterase PF00756.20 ABK72057.1 - 0.0013 18.4 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 ABK72057.1 - 0.0053 16.9 0.1 0.0083 16.3 0.1 1.3 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 ABK72057.1 - 0.023 14.4 0.0 2.2 7.9 0.0 2.1 2 0 0 2 2 2 0 PGAP1-like protein PAF-AH_p_II PF03403.13 ABK72057.1 - 0.081 11.4 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II UPF0227 PF05728.12 ABK72057.1 - 0.086 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Lipase_3 PF01764.25 ABK72057.1 - 0.14 12.0 0.2 0.25 11.2 0.2 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.16 ABK72057.1 - 0.21 11.4 0.0 1.3 8.8 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase BPD_transp_1 PF00528.22 ABK72058.1 - 9.2e-45 152.6 12.7 9.2e-45 152.6 12.7 2.5 2 1 1 3 3 3 1 Binding-protein-dependent transport system inner membrane component adh_short PF00106.25 ABK72059.1 - 1.4e-25 89.9 0.2 1.6e-25 89.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK72059.1 - 8.1e-18 64.8 1.1 1e-17 64.5 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK72059.1 - 0.00048 20.1 0.7 0.00081 19.3 0.7 1.4 1 1 0 1 1 1 1 KR domain Xan_ur_permease PF00860.20 ABK72060.1 - 1.6e-30 106.1 46.0 1.6e-30 106.1 46.0 1.6 1 1 1 2 2 2 1 Permease family Bac_luciferase PF00296.20 ABK72062.1 - 1.1e-34 120.2 5.5 4.4e-34 118.3 5.5 1.7 1 1 0 1 1 1 1 Luciferase-like monooxygenase DHDPS PF00701.22 ABK72063.1 - 2.2e-56 190.7 0.0 2.6e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family GHMP_kinases_C PF08544.13 ABK72063.1 - 0.06 13.7 0.7 5.9 7.3 0.3 3.0 3 0 0 3 3 3 0 GHMP kinases C terminal SBP_bac_1 PF01547.25 ABK72064.1 - 4.1e-52 178.1 5.8 6.9e-52 177.4 5.8 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 ABK72064.1 - 2.8e-33 116.0 2.5 3.9e-33 115.5 2.5 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein AFG1_ATPase PF03969.16 ABK72065.1 - 5.2e-86 288.8 0.0 1e-59 202.3 0.0 2.0 1 1 1 2 2 2 2 AFG1-like ATPase IstB_IS21 PF01695.17 ABK72065.1 - 0.035 13.8 0.0 0.069 12.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.6 ABK72065.1 - 0.086 13.2 1.1 6.1 7.2 0.0 2.9 1 1 2 3 3 3 0 AAA ATPase domain MobB PF03205.14 ABK72065.1 - 0.11 12.4 0.0 0.59 10.0 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.12 ABK72065.1 - 0.19 11.6 0.1 4 7.3 0.1 2.9 4 0 0 4 4 4 0 NACHT domain Complex1_51K PF01512.17 ABK72066.1 - 1.3e-32 112.7 0.0 1.9e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 ABK72066.1 - 5e-15 55.3 0.1 5e-15 55.3 0.1 1.7 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region FMN_dh PF01070.18 ABK72067.1 - 2.8e-109 365.3 0.1 3.2e-109 365.1 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 ABK72067.1 - 3e-07 29.8 2.2 1.1e-06 27.9 1.7 2.0 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 ABK72067.1 - 1.1e-06 28.1 0.4 1.7e-06 27.5 0.4 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 ABK72067.1 - 0.001 18.4 0.2 0.0024 17.2 0.2 1.7 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 ABK72067.1 - 0.0028 17.1 0.6 0.048 13.1 0.2 2.2 1 1 1 2 2 2 1 Histidine biosynthesis protein NMO PF03060.15 ABK72067.1 - 0.004 16.6 1.7 0.0067 15.9 1.7 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase G3P_antiterm PF04309.12 ABK72067.1 - 0.012 15.0 0.0 3.7 6.9 0.0 2.3 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Dus PF01207.17 ABK72067.1 - 0.046 12.8 0.2 0.075 12.1 0.2 1.3 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 ABK72067.1 - 0.046 12.9 0.4 0.09 12.0 0.4 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase PA PF02225.22 ABK72067.1 - 0.09 12.8 0.1 0.09 12.8 0.1 2.6 2 1 1 3 3 3 0 PA domain IGPS PF00218.21 ABK72067.1 - 0.14 11.3 0.1 9.8 5.3 0.0 2.8 3 0 0 3 3 3 0 Indole-3-glycerol phosphate synthase bPH_6 PF10756.9 ABK72068.1 - 7.6e-20 70.8 4.1 7.6e-20 70.8 4.1 1.5 2 0 0 2 2 2 1 Bacterial PH domain GPP34 PF05719.11 ABK72069.1 - 2.1e-26 93.3 0.5 2.4e-26 93.0 0.5 1.0 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) LysR_substrate PF03466.20 ABK72070.1 - 1.8e-20 73.2 5.3 1.8e-20 73.2 5.3 1.5 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 ABK72070.1 - 4.2e-14 52.2 1.8 7.3e-14 51.5 1.8 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 ABK72070.1 - 0.022 14.7 0.8 0.06 13.3 0.8 1.8 1 0 0 1 1 1 0 MarR family SBP_bac_3 PF00497.20 ABK72070.1 - 0.13 11.7 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 TctC PF03401.14 ABK72071.1 - 6.4e-25 87.7 0.0 7.4e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter family receptor Phosphonate-bd PF12974.7 ABK72071.1 - 0.014 15.0 0.3 0.076 12.6 0.3 1.9 1 1 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein FR47 PF08445.10 ABK72072.1 - 4.1e-08 33.1 0.0 7.6e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 ABK72072.1 - 1.3e-07 31.9 0.0 2.6e-07 30.9 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 ABK72072.1 - 2.6e-05 23.9 0.2 0.0021 17.7 0.1 2.2 1 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ABK72072.1 - 2.8e-05 24.5 0.0 4.8e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ABK72072.1 - 2.9e-05 24.0 0.0 4.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ABK72072.1 - 0.00055 20.0 0.1 0.001 19.1 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ABK72072.1 - 0.00057 20.6 0.0 0.0011 19.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 ABK72072.1 - 0.0096 15.5 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_CG PF14542.6 ABK72072.1 - 0.05 13.7 0.0 0.095 12.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase MFS_1 PF07690.16 ABK72073.1 - 8.4e-56 189.4 69.6 5.9e-48 163.6 35.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK72073.1 - 2.8e-23 82.5 39.8 1.7e-22 79.9 39.5 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 ABK72073.1 - 3.7e-14 52.8 13.2 3.7e-14 52.8 13.2 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 ABK72073.1 - 8.8e-05 21.2 45.1 0.00037 19.2 9.1 3.3 2 2 2 4 4 4 3 MFS/sugar transport protein MFS_1_like PF12832.7 ABK72073.1 - 0.00012 21.1 7.1 0.00012 21.1 7.1 2.3 2 0 0 2 2 2 1 MFS_1 like family TMEM43 PF07787.12 ABK72073.1 - 2.9 7.2 12.0 1.6 8.0 6.3 2.6 2 0 0 2 2 2 0 Transmembrane protein 43 ATP-synt_A PF00119.20 ABK72074.1 - 2.3e-48 165.0 17.8 2.9e-48 164.6 17.8 1.1 1 0 0 1 1 1 1 ATP synthase A chain HypA PF01155.19 ABK72075.1 - 1.6e-33 115.0 0.5 1.8e-33 114.9 0.5 1.0 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1451 PF07295.11 ABK72075.1 - 0.0097 15.9 0.1 0.011 15.8 0.1 1.2 1 0 0 1 1 1 1 Zinc-ribbon containing domain Zn-ribbon_8 PF09723.10 ABK72075.1 - 0.0099 16.0 0.4 0.018 15.1 0.4 1.4 1 0 0 1 1 1 1 Zinc ribbon domain DZR PF12773.7 ABK72075.1 - 0.11 12.6 1.3 0.28 11.2 1.5 1.7 1 1 0 1 1 1 0 Double zinc ribbon DNA_RNApol_7kD PF03604.13 ABK72075.1 - 0.12 12.0 1.4 0.22 11.2 1.4 1.4 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit zf-NADH-PPase PF09297.11 ABK72075.1 - 0.19 11.4 2.9 0.36 10.5 2.9 1.5 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain zf-dskA_traR PF01258.17 ABK72075.1 - 0.21 11.5 2.1 0.23 11.4 0.3 2.0 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Zn_Tnp_IS1 PF03811.13 ABK72075.1 - 0.23 11.2 0.1 0.23 11.2 0.1 2.3 3 0 0 3 3 3 0 InsA N-terminal domain DUF456 PF04306.13 ABK72076.1 - 1.2e-31 109.9 30.3 1.2e-31 109.9 30.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF456) DUF2232 PF09991.9 ABK72076.1 - 0.0013 18.0 1.8 0.0013 18.0 1.8 2.7 1 1 1 2 2 2 1 Predicted membrane protein (DUF2232) DUF4112 PF13430.6 ABK72076.1 - 0.066 13.5 0.4 0.066 13.5 0.4 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4112) Rax2 PF12768.7 ABK72076.1 - 3.7 6.9 4.3 6.8 6.1 4.3 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity ADP_ribosyl_GH PF03747.14 ABK72077.1 - 3.9e-47 161.4 8.9 6.1e-47 160.8 8.9 1.3 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase DSPc PF00782.20 ABK72077.1 - 0.00018 21.3 0.0 0.00029 20.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Bacteriocin_IIc PF10439.9 ABK72077.1 - 7.9 6.7 9.5 11 6.3 0.9 2.5 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Imm17 PF15562.6 ABK72078.1 - 0.07 13.0 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Immunity protein 17 SH3_5 PF08460.10 ABK72078.1 - 0.11 12.6 0.2 0.22 11.6 0.2 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain MarR PF01047.22 ABK72079.1 - 3.5e-13 49.2 0.1 6.7e-13 48.4 0.1 1.4 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 ABK72079.1 - 1e-11 44.5 0.9 3e-11 43.0 0.9 1.8 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 ABK72079.1 - 1.8e-09 37.9 0.1 3.5e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 ABK72079.1 - 0.00019 21.2 1.7 0.00019 21.2 1.7 2.3 2 1 1 3 3 3 1 IclR helix-turn-helix domain HTH_24 PF13412.6 ABK72079.1 - 0.00021 20.8 0.8 0.00049 19.6 0.1 2.0 2 1 1 3 3 3 1 Winged helix-turn-helix DNA-binding Rrf2 PF02082.20 ABK72079.1 - 0.00037 20.8 0.2 0.00083 19.7 0.0 1.7 2 0 0 2 2 2 1 Transcriptional regulator Fe_dep_repress PF01325.19 ABK72079.1 - 0.0018 18.4 0.2 0.014 15.6 0.1 2.1 1 1 1 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain HxlR PF01638.17 ABK72079.1 - 0.0061 16.4 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 HxlR-like helix-turn-helix TrmB PF01978.19 ABK72079.1 - 0.03 14.2 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.7 ABK72079.1 - 0.087 12.9 0.5 0.087 12.9 0.5 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain DDE_3 PF13358.6 ABK72080.1 - 3e-24 85.4 0.0 4.5e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 ABK72080.1 - 4e-15 56.2 6.4 1.6e-14 54.3 0.7 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.6 ABK72080.1 - 9e-14 51.2 3.6 3.2e-13 49.5 0.4 3.2 3 0 0 3 3 3 1 Winged helix-turn helix HTH_28 PF13518.6 ABK72080.1 - 1.5e-13 50.6 5.9 3.5e-11 43.1 0.4 3.1 3 0 0 3 3 2 2 Helix-turn-helix domain HTH_23 PF13384.6 ABK72080.1 - 1.5e-12 46.9 1.7 3.6e-09 36.1 0.4 3.2 2 1 1 3 3 3 2 Homeodomain-like domain HTH_50 PF18024.1 ABK72080.1 - 0.00034 20.2 0.2 0.0013 18.3 0.0 2.1 3 0 0 3 3 2 1 Helix-turn-helix domain HTH_24 PF13412.6 ABK72080.1 - 0.00071 19.1 0.1 0.039 13.5 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_6 PF01418.17 ABK72080.1 - 0.001 19.0 0.0 0.0036 17.2 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain, rpiR family HTH_IclR PF09339.10 ABK72080.1 - 0.0015 18.3 0.6 0.059 13.2 0.0 2.4 2 0 0 2 2 2 1 IclR helix-turn-helix domain YdaS_antitoxin PF15943.5 ABK72080.1 - 0.003 17.4 0.2 0.9 9.5 0.0 2.9 3 0 0 3 3 3 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Sigma70_r4_2 PF08281.12 ABK72080.1 - 0.0046 16.6 0.0 0.051 13.3 0.0 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_26 PF13443.6 ABK72080.1 - 0.0058 17.0 0.6 0.99 9.9 0.0 3.1 3 0 0 3 3 3 1 Cro/C1-type HTH DNA-binding domain HTH_Crp_2 PF13545.6 ABK72080.1 - 0.0068 16.4 0.1 2.6 8.1 0.0 2.5 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_AsnC-type PF13404.6 ABK72080.1 - 0.0089 15.8 0.1 0.64 9.9 0.0 2.5 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_37 PF13744.6 ABK72080.1 - 0.026 14.5 0.0 0.47 10.5 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.7 ABK72080.1 - 0.034 14.3 0.4 3.3 8.0 0.0 3.1 3 0 0 3 3 2 0 Helix-turn-helix domain MarR PF01047.22 ABK72080.1 - 0.044 13.7 0.0 12 5.9 0.0 2.5 2 0 0 2 2 2 0 MarR family HTH_36 PF13730.6 ABK72080.1 - 0.044 13.7 0.0 0.34 10.9 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 ABK72080.1 - 0.048 14.2 1.5 0.056 14.0 0.1 1.8 2 0 0 2 2 1 0 leucine-zipper of insertion element IS481 HTH_Tnp_ISL3 PF13542.6 ABK72080.1 - 0.049 13.0 4.2 0.054 12.9 0.7 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4 PF04545.16 ABK72080.1 - 0.056 13.0 0.1 3.2 7.3 0.0 2.7 2 0 0 2 2 2 0 Sigma-70, region 4 GerE PF00196.19 ABK72080.1 - 0.084 12.4 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family DUF746 PF05344.11 ABK72080.1 - 0.13 12.1 0.8 2.5 8.0 0.0 3.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF746) HTH_3 PF01381.22 ABK72080.1 - 0.18 11.9 0.0 14 5.9 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix Acetyltransf_1 PF00583.25 ABK72081.1 - 4.2e-14 52.8 0.2 6.3e-14 52.2 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ABK72081.1 - 2.7e-13 50.1 0.2 4.7e-13 49.4 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ABK72081.1 - 7.3e-10 38.9 0.0 1.1e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ABK72081.1 - 2.8e-05 24.2 0.0 0.00024 21.2 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ABK72081.1 - 0.00062 19.8 0.0 0.00099 19.2 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 ABK72081.1 - 0.005 16.8 0.1 0.0089 16.0 0.1 1.4 1 1 0 1 1 1 1 FR47-like protein NodA PF02474.15 ABK72081.1 - 0.043 13.5 0.1 0.077 12.7 0.1 1.4 1 0 0 1 1 1 0 Nodulation protein A (NodA) Acetyltransf_4 PF13420.7 ABK72081.1 - 0.054 13.6 0.0 0.071 13.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ABK72081.1 - 0.13 12.9 0.0 0.17 12.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DDE_Tnp_1_4 PF13701.6 ABK72082.1 - 4.5e-29 101.0 0.0 7e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain group 1 DDE_Tnp_1 PF01609.21 ABK72082.1 - 6.4e-06 26.0 0.0 1.2e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 Transposase DDE domain Calycin_like PF13944.6 ABK72083.1 - 0.66 10.3 3.3 37 4.6 3.3 2.8 1 1 0 1 1 1 0 Calycin-like beta-barrel domain Sporozoite_P67 PF05642.11 ABK72083.1 - 2 6.4 20.8 22 3.0 20.7 2.0 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Thioredoxin_4 PF13462.6 ABK72084.1 - 3.1e-12 47.0 0.0 4.3e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 ABK72084.1 - 0.011 15.5 0.1 0.71 9.6 0.0 2.4 2 1 0 2 2 2 0 DSBA-like thioredoxin domain CxC7 PF18866.1 ABK72084.1 - 0.016 15.3 0.1 0.028 14.6 0.1 1.3 1 0 0 1 1 1 0 CxC7 like cysteine cluster associated with KDZ transposases TetR_N PF00440.23 ABK72085.1 - 6.5e-17 61.1 1.7 3.2e-15 55.6 0.4 2.7 3 0 0 3 3 3 1 Bacterial regulatory proteins, tetR family HTH_Tnp_1_2 PF13022.6 ABK72085.1 - 0.0016 18.6 0.0 0.0028 17.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of insertion element transposase Sigma70_r4 PF04545.16 ABK72085.1 - 0.05 13.1 0.1 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_7 PF02796.15 ABK72085.1 - 0.098 12.8 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase DHQ_synthase PF01761.20 ABK72086.1 - 3e-91 305.2 0.0 3.8e-91 304.9 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 ABK72086.1 - 1.1e-10 41.7 2.8 1.2e-09 38.3 0.4 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 ABK72086.1 - 1.2e-06 27.6 5.4 3.2e-06 26.2 5.4 1.8 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Aminotran_1_2 PF00155.21 ABK72087.1 - 2.1e-22 79.8 0.0 2.5e-22 79.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 ABK72087.1 - 5.8e-10 38.7 0.1 5.8e-10 38.7 0.1 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family Aminotran_MocR PF12897.7 ABK72087.1 - 1.3e-06 27.4 0.0 6.9e-06 25.1 0.0 1.9 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase HAD_SAK_2 PF18143.1 ABK72087.1 - 0.011 16.0 0.1 0.069 13.5 0.0 2.1 2 0 0 2 2 2 0 HAD domain in Swiss Army Knife RNA repair proteins Rrf2 PF02082.20 ABK72087.1 - 0.12 12.8 0.0 0.33 11.3 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator HTH_27 PF13463.6 ABK72087.1 - 0.14 12.7 0.3 25 5.5 0.0 2.5 2 0 0 2 2 2 0 Winged helix DNA-binding domain Amidohydro_3 PF07969.11 ABK72089.1 - 1.9e-90 304.6 13.2 2.2e-90 304.4 13.2 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 ABK72089.1 - 4.7e-07 29.5 0.0 7.2e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family DUF2993 PF11209.8 ABK72090.1 - 1.2e-23 84.5 0.3 1.8e-23 83.9 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2993) Amidase PF01425.21 ABK72091.1 - 1.2e-100 337.6 0.1 3e-100 336.3 0.1 1.5 1 1 0 1 1 1 1 Amidase MHB PF16525.5 ABK72092.1 - 3.9e-33 113.5 0.0 4.9e-33 113.2 0.0 1.1 1 0 0 1 1 1 1 Haemophore, haem-binding ScsC_N PF18312.1 ABK72092.1 - 0.0036 17.1 0.0 0.15 11.9 0.1 2.2 2 0 0 2 2 2 1 Copper resistance protein ScsC N-terminal domain DUF3775 PF12616.8 ABK72092.1 - 0.19 11.7 0.0 5.4 7.1 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3775) DUF1707 PF08044.11 ABK72093.1 - 2.7e-18 65.8 2.5 4.6e-18 65.0 2.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1707) 2TM PF13239.6 ABK72093.1 - 2.4e-08 34.2 0.8 3.5e-08 33.6 0.8 1.2 1 0 0 1 1 1 1 2TM domain Acetyltransf_1 PF00583.25 ABK72094.1 - 2.6e-08 34.1 0.0 5.3e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ABK72094.1 - 2.5e-05 24.6 0.0 5.4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ABK72094.1 - 0.00019 21.4 0.0 0.00033 20.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ABK72094.1 - 0.041 14.0 0.0 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 ABK72094.1 - 0.043 13.8 0.1 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 FR47-like protein UDPG_MGDP_dh PF00984.19 ABK72094.1 - 0.16 12.2 0.0 0.42 10.8 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain T7SS_ESX_EspC PF10824.8 ABK72095.1 - 3.7e-30 104.3 7.6 4.1e-30 104.2 7.6 1.0 1 0 0 1 1 1 1 Excreted virulence factor EspC, type VII ESX diderm UreF PF01730.16 ABK72095.1 - 0.039 14.5 2.3 0.054 14.1 2.4 1.4 1 1 0 1 1 1 0 UreF PE PF00934.20 ABK72095.1 - 0.073 13.4 5.2 0.096 13.0 5.2 1.1 1 0 0 1 1 1 0 PE family Usp PF00582.26 ABK72096.1 - 2.3e-20 73.5 4.7 8.7e-20 71.7 1.8 2.2 2 0 0 2 2 2 1 Universal stress protein family Amidohydro_3 PF07969.11 ABK72097.1 - 6.7e-48 164.3 6.7 8e-48 164.1 6.7 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 ABK72097.1 - 2.1e-06 27.3 0.0 0.0029 17.0 0.0 2.9 3 0 0 3 3 3 2 Amidohydrolase family Ribosomal_S2 PF00318.20 ABK72098.1 - 1.3e-98 328.5 0.0 1.5e-98 328.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S2 PucR PF07905.11 ABK72098.1 - 0.08 13.2 0.0 1.9 8.8 0.0 2.3 2 0 0 2 2 2 0 Purine catabolism regulatory protein-like family Glycos_transf_2 PF00535.26 ABK72099.1 - 5.4e-21 75.1 0.0 9.1e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 ABK72099.1 - 1.1e-15 57.9 0.0 1.8e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 ABK72099.1 - 4.9e-11 42.4 0.0 1.1e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 ABK72099.1 - 5.8e-11 42.7 0.3 1.3e-10 41.6 0.3 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ABK72099.1 - 3.3e-10 40.2 2.0 5e-10 39.6 2.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_7C PF02709.14 ABK72099.1 - 0.052 13.2 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase Glyco_transf_49 PF13896.6 ABK72099.1 - 0.09 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl-transferase for dystroglycan Excalibur PF05901.11 ABK72100.1 - 3.8e-15 56.2 2.2 5.2e-15 55.8 2.2 1.2 1 0 0 1 1 1 1 Excalibur calcium-binding domain adh_short_C2 PF13561.6 ABK72101.1 - 1.9e-54 184.7 3.2 2.3e-54 184.4 3.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK72101.1 - 1.2e-48 165.2 0.7 1.4e-48 165.0 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK72101.1 - 1.3e-12 48.0 1.2 1.7e-12 47.6 1.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK72101.1 - 4.2e-05 23.1 0.0 6.2e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family UTRA PF07702.13 ABK72103.1 - 6.3e-38 129.8 0.1 9.3e-38 129.3 0.1 1.3 1 0 0 1 1 1 1 UTRA domain GntR PF00392.21 ABK72103.1 - 8.8e-15 54.1 0.6 1.6e-14 53.3 0.6 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Rrf2 PF02082.20 ABK72103.1 - 3e-05 24.3 0.1 5.2e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulator HTH_20 PF12840.7 ABK72103.1 - 0.00013 22.0 1.4 0.00033 20.7 1.4 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_41 PF14502.6 ABK72103.1 - 0.0053 16.4 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 ABK72103.1 - 0.046 13.7 0.3 0.13 12.2 0.3 1.9 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_29 PF13551.6 ABK72103.1 - 0.061 13.4 0.5 0.15 12.1 0.5 1.8 1 0 0 1 1 1 0 Winged helix-turn helix RepL PF05732.11 ABK72103.1 - 0.069 12.6 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) FaeA PF04703.12 ABK72103.1 - 0.15 12.4 0.0 0.38 11.2 0.0 1.7 1 0 0 1 1 1 0 FaeA-like protein FGGY_N PF00370.21 ABK72104.1 - 1.4e-74 250.7 0.0 2e-74 250.2 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 ABK72104.1 - 1.5e-68 230.5 0.8 2e-67 226.8 0.6 2.1 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain ECH_1 PF00378.20 ABK72105.1 - 4.7e-33 114.5 0.0 2e-31 109.2 0.0 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK72105.1 - 8.4e-19 68.2 0.0 1e-18 68.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Beta-lactamase PF00144.24 ABK72105.1 - 0.032 13.5 0.1 0.047 12.9 0.1 1.2 1 0 0 1 1 1 0 Beta-lactamase Sel1 PF08238.12 ABK72105.1 - 1.2 10.0 4.5 1.6 9.5 1.9 2.7 2 1 0 2 2 2 0 Sel1 repeat DUF2171 PF09939.9 ABK72106.1 - 0.039 14.2 0.2 0.04 14.2 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2171) Amidase PF01425.21 ABK72107.1 - 1.9e-109 366.6 0.5 5.4e-109 365.1 0.5 1.6 1 1 0 1 1 1 1 Amidase Cupin_2 PF07883.11 ABK72108.1 - 2.7e-13 49.4 0.2 3.9e-13 48.9 0.2 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 ABK72108.1 - 6.9e-06 25.7 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_7 PF12973.7 ABK72108.1 - 0.00092 19.1 0.0 0.0018 18.1 0.0 1.5 1 1 0 1 1 1 1 ChrR Cupin-like domain Cupin_3 PF05899.12 ABK72108.1 - 0.0053 16.4 0.0 0.0095 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) DMSP_lyase PF16867.5 ABK72108.1 - 0.0062 16.2 0.0 0.009 15.7 0.0 1.2 1 0 0 1 1 1 1 Dimethlysulfonioproprionate lyase AraC_binding PF02311.19 ABK72108.1 - 0.026 14.4 0.1 0.034 14.1 0.1 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain PCO_ADO PF07847.12 ABK72108.1 - 0.029 13.8 0.2 0.076 12.5 0.2 1.7 1 1 0 1 1 1 0 PCO_ADO Cys_Met_Meta_PP PF01053.20 ABK72109.1 - 8.9e-143 475.4 0.0 1e-142 475.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 ABK72109.1 - 9.1e-05 21.9 0.0 0.0014 18.0 0.0 2.2 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 ABK72109.1 - 0.00023 20.2 0.0 0.00037 19.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 ABK72109.1 - 0.0031 16.9 0.1 0.0055 16.1 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family ABC2_membrane_2 PF12679.7 ABK72110.1 - 0.004 16.5 11.5 0.0077 15.6 11.5 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 ABK72110.1 - 0.29 10.2 7.6 0.13 11.3 5.1 1.6 1 1 1 2 2 2 0 ABC-2 family transporter protein Methyltransf_11 PF08241.12 ABK72111.1 - 8.8e-24 84.0 0.1 1.7e-23 83.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABK72111.1 - 1.8e-19 70.2 0.0 3.3e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABK72111.1 - 1.6e-14 54.0 0.0 2e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABK72111.1 - 2.5e-14 53.5 0.0 4.5e-14 52.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK72111.1 - 3.2e-11 43.8 0.0 6.1e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ABK72111.1 - 1.1e-05 24.8 0.0 2.7e-05 23.6 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 ABK72111.1 - 2e-05 24.6 0.0 3.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase CMAS PF02353.20 ABK72111.1 - 0.00024 20.5 0.0 0.00035 19.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 ABK72111.1 - 0.00067 19.3 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 ABK72111.1 - 0.014 15.4 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_29 PF03141.16 ABK72111.1 - 0.052 12.1 0.0 0.065 11.8 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase TPMT PF05724.11 ABK72111.1 - 0.068 12.8 0.0 0.43 10.2 0.0 1.9 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_9 PF08003.11 ABK72111.1 - 0.11 11.4 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Glyco_transf_28 PF03033.20 ABK72112.1 - 1.7e-09 37.8 0.0 3.2e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 ABK72112.1 - 0.13 11.1 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Putative_PNPOx PF01243.20 ABK72113.1 - 0.00027 21.0 0.0 0.0004 20.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase BPD_transp_1 PF00528.22 ABK72114.1 - 4.3e-25 88.5 9.8 4.3e-25 88.5 9.8 1.6 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component FeoB_C PF07664.12 ABK72114.1 - 0.059 13.1 0.1 0.059 13.1 0.1 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus Pyr_redox_3 PF13738.6 ABK72115.1 - 2.8e-18 66.2 0.0 9.5e-18 64.5 0.0 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ABK72115.1 - 2.5e-15 55.9 0.0 9.9e-13 47.3 0.0 2.9 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 ABK72115.1 - 2.1e-12 46.9 0.0 9e-10 38.2 0.0 3.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 ABK72115.1 - 4.1e-11 42.7 0.0 1.2e-08 34.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ABK72115.1 - 1.1e-10 41.5 0.1 4.7e-10 39.5 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 ABK72115.1 - 5.5e-07 29.2 0.0 0.022 14.0 0.0 2.3 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 ABK72115.1 - 5.3e-06 26.2 1.6 0.0029 17.2 0.2 3.2 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ABK72115.1 - 8.4e-06 25.9 2.5 0.1 12.6 0.0 3.8 4 0 0 4 4 4 2 FAD-NAD(P)-binding Pyr_redox PF00070.27 ABK72115.1 - 5.2e-05 23.7 0.4 0.049 14.2 0.1 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ABK72115.1 - 8.4e-05 21.8 0.0 0.00012 21.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 ABK72115.1 - 0.0057 16.1 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 ABK72115.1 - 0.011 14.8 1.3 0.48 9.4 0.3 2.4 3 0 0 3 3 3 0 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 ABK72115.1 - 0.013 14.9 0.0 0.033 13.6 0.0 1.7 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ABK72115.1 - 0.028 13.7 0.3 0.84 8.9 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 ABK72115.1 - 0.041 13.1 0.1 0.091 12.0 0.1 1.5 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 ABK72115.1 - 0.056 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 ABK72115.1 - 0.19 10.4 0.1 0.7 8.5 0.2 1.9 3 0 0 3 3 3 0 HI0933-like protein IlvN PF07991.12 ABK72115.1 - 0.2 11.2 0.2 1.8 8.1 0.0 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain MFS_1 PF07690.16 ABK72116.1 - 9.6e-26 90.5 43.5 9.6e-26 90.5 43.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribonuc_red_sm PF00268.21 ABK72117.1 - 9.7e-94 313.9 0.4 1.1e-93 313.7 0.4 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF1289 PF06945.13 ABK72117.1 - 0.15 11.9 1.5 13 5.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1289) FlgO PF17680.1 ABK72118.1 - 0.19 11.5 0.0 0.27 11.0 0.0 1.1 1 0 0 1 1 1 0 FlgO protein Acyl-CoA_dh_1 PF00441.24 ABK72120.1 - 2.5e-45 154.4 0.2 3.6e-45 153.8 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK72120.1 - 2.9e-28 97.9 0.0 5.6e-28 97.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ABK72120.1 - 1.2e-27 96.7 0.0 2.4e-27 95.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ABK72120.1 - 3.2e-10 40.4 0.1 5e-10 39.8 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 ABK72120.1 - 0.0026 18.3 0.0 0.0055 17.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Hemerythrin PF01814.23 ABK72121.1 - 0.0018 18.9 0.2 0.0026 18.4 0.2 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Amidase PF01425.21 ABK72122.1 - 1.8e-90 304.1 5.0 2.6e-90 303.5 5.0 1.2 1 0 0 1 1 1 1 Amidase GT87 PF09594.10 ABK72123.1 - 6.6e-35 120.9 29.4 6.6e-35 120.9 29.4 2.1 2 0 0 2 2 2 1 Glycosyltransferase family 87 Saf_2TM PF18303.1 ABK72123.1 - 0.77 9.3 4.1 0.87 9.2 0.4 2.8 2 1 1 3 3 3 0 SAVED-fused 2TM effector domain Dak1 PF02733.17 ABK72124.1 - 7.8e-105 350.2 0.0 1e-104 349.8 0.0 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 ABK72124.1 - 1.3e-41 142.4 12.9 1.3e-41 142.4 12.9 1.5 2 0 0 2 2 2 1 DAK2 domain FAD_oxidored PF12831.7 ABK72125.1 - 3.1e-95 320.1 3.3 3.5e-95 319.9 3.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ABK72125.1 - 2.2e-07 30.3 19.0 3.8e-06 26.2 13.7 2.3 1 1 1 2 2 2 2 FAD binding domain Thi4 PF01946.17 ABK72125.1 - 1e-06 28.2 9.1 1.6e-05 24.2 9.1 2.3 1 1 0 1 1 1 1 Thi4 family DAO PF01266.24 ABK72125.1 - 2.9e-05 23.8 14.1 0.00092 18.9 9.0 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ABK72125.1 - 0.00012 21.5 3.3 0.00025 20.4 3.3 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ABK72125.1 - 0.00024 20.5 6.7 0.0011 18.3 6.7 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ABK72125.1 - 0.0017 18.6 8.4 0.0061 16.8 6.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ABK72125.1 - 0.0023 16.7 8.4 0.0043 15.8 8.1 1.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 ABK72125.1 - 0.0027 17.0 3.6 0.0043 16.4 3.6 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ABK72125.1 - 0.023 13.8 8.2 0.035 13.2 8.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 ABK72125.1 - 0.025 15.2 4.1 1.6 9.3 4.5 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ABK72125.1 - 0.041 12.9 6.9 0.17 10.9 6.9 1.9 1 1 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.18 ABK72125.1 - 0.16 11.9 6.4 0.25 11.2 6.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ABK72125.1 - 0.32 10.3 6.7 0.76 9.0 6.7 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Fer2 PF00111.27 ABK72126.1 - 2.1e-12 46.8 0.1 5e-12 45.6 0.1 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.21 ABK72126.1 - 2.6e-12 47.3 0.0 1e-11 45.4 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 ABK72126.1 - 4.8e-11 42.9 0.0 7.7e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 ABK72126.1 - 0.009 16.1 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 ABK72126.1 - 0.021 15.1 0.0 0.038 14.2 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain MlaE PF02405.16 ABK72127.1 - 1.3e-55 188.4 25.2 1.5e-55 188.2 25.2 1.0 1 0 0 1 1 1 1 Permease MlaE 4HBT PF03061.22 ABK72128.1 - 1.9e-10 40.9 0.7 9.8e-10 38.7 0.6 2.1 2 0 0 2 2 2 1 Thioesterase superfamily 4HBT_3 PF13622.6 ABK72128.1 - 4.3e-06 27.2 3.5 0.01 16.1 0.7 2.9 3 0 0 3 3 3 2 Thioesterase-like superfamily Glyoxalase PF00903.25 ABK72129.1 - 3.7e-11 43.3 0.1 5.9e-11 42.7 0.1 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ABK72129.1 - 5.1e-10 40.1 0.2 8.4e-10 39.4 0.2 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 ABK72129.1 - 0.0054 17.0 0.0 0.0084 16.4 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3-dmu-9_3-mt PF06983.13 ABK72129.1 - 0.015 15.8 0.0 0.065 13.8 0.0 1.9 1 1 0 1 1 1 0 3-demethylubiquinone-9 3-methyltransferase Glyoxalase_2 PF12681.7 ABK72129.1 - 0.14 12.1 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Glyoxalase-like domain Bac_luciferase PF00296.20 ABK72130.1 - 3.2e-71 240.3 8.8 3.7e-71 240.1 8.8 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Helicase_C_2 PF13307.6 ABK72131.1 - 3.3e-30 105.5 0.0 4.8e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD PF00270.29 ABK72131.1 - 5.2e-10 39.4 0.1 3e-05 23.9 0.1 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 ABK72131.1 - 4.8e-05 23.4 0.0 0.024 14.6 0.0 2.1 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD_2 PF06733.15 ABK72131.1 - 0.25 11.0 0.0 0.39 10.3 0.0 1.3 1 0 0 1 1 1 0 DEAD_2 adh_short PF00106.25 ABK72132.1 - 2e-30 105.7 0.9 2.6e-30 105.4 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK72132.1 - 4.4e-20 72.2 0.7 5.5e-20 71.9 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK72132.1 - 1.8e-09 37.8 1.2 3e-09 37.0 1.2 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK72132.1 - 6.9e-05 22.4 1.0 0.00018 21.0 1.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ABK72132.1 - 0.00078 19.4 1.9 0.001 19.0 1.9 1.4 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 ABK72132.1 - 0.011 14.9 0.3 0.022 13.9 0.3 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Glyco_hydro_65m PF03632.15 ABK72133.1 - 2e-143 478.0 0.0 2.5e-143 477.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.15 ABK72133.1 - 4.5e-69 232.6 0.0 6.6e-69 232.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.15 ABK72133.1 - 4.5e-11 42.5 0.0 2.7e-10 40.0 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, C-terminal domain LRR19-TM PF15176.6 ABK72133.1 - 0.031 14.3 0.0 0.089 12.8 0.0 1.7 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain HxlR PF01638.17 ABK72134.1 - 1.3e-26 92.3 0.0 1.6e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix PadR PF03551.14 ABK72134.1 - 0.0093 15.9 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family GntR PF00392.21 ABK72134.1 - 0.019 14.6 0.3 0.034 13.8 0.3 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_CodY PF08222.11 ABK72134.1 - 0.029 13.9 0.1 0.046 13.3 0.1 1.3 1 0 0 1 1 1 0 CodY helix-turn-helix domain Replic_Relax PF13814.6 ABK72134.1 - 0.066 13.3 0.1 0.1 12.7 0.0 1.3 1 1 0 1 1 1 0 Replication-relaxation MarR PF01047.22 ABK72134.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 MarR family Glyco_tran_28_C PF04101.16 ABK72136.1 - 4.3e-09 36.6 0.1 6.7e-09 35.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Alg14 PF08660.11 ABK72136.1 - 0.046 13.7 0.0 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 Oligosaccharide biosynthesis protein Alg14 like Peptidase_S15 PF02129.18 ABK72137.1 - 3.1e-45 154.9 0.1 2.4e-39 135.6 0.2 2.1 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 ABK72137.1 - 2e-27 96.6 0.1 5.5e-27 95.2 0.1 1.7 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 ABK72137.1 - 0.0049 16.2 0.0 0.071 12.4 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 ABK72137.1 - 0.17 11.4 0.0 1.2 8.6 0.0 2.1 1 1 0 1 1 1 0 Prolyl oligopeptidase family FAD_binding_2 PF00890.24 ABK72138.1 - 3.9e-107 358.9 1.2 4.4e-107 358.7 1.2 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ABK72138.1 - 1.9e-07 31.2 1.1 1.3e-06 28.5 0.6 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 ABK72138.1 - 1.2e-06 28.0 0.2 1.9e-06 27.4 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 ABK72138.1 - 2e-05 24.2 0.2 3.2e-05 23.5 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 ABK72138.1 - 6.2e-05 22.3 0.4 0.00015 21.1 0.4 1.6 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 ABK72138.1 - 8.4e-05 21.4 2.0 8.9e-05 21.4 0.7 1.6 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 ABK72138.1 - 9.1e-05 22.2 6.0 0.0003 20.5 6.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 ABK72138.1 - 0.00015 21.0 1.4 0.00034 19.8 1.4 1.6 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 ABK72138.1 - 0.00028 20.2 0.7 0.00028 20.2 0.7 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ABK72138.1 - 0.0013 18.7 0.1 0.0035 17.3 0.1 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 ABK72138.1 - 0.0015 19.0 1.2 0.02 15.5 1.5 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ABK72138.1 - 0.0026 16.9 0.7 0.0026 16.9 0.7 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 ABK72138.1 - 0.0092 15.3 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 ABK72138.1 - 0.0098 15.5 0.5 0.015 14.9 0.5 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 ABK72138.1 - 0.014 14.7 0.4 0.025 13.9 0.4 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ABC_tran PF00005.27 ABK72139.1 - 2.5e-32 112.3 0.0 3.5e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ABK72139.1 - 6.1e-06 25.8 0.0 0.0015 18.0 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ABK72139.1 - 1.4e-05 25.4 0.2 0.0001 22.6 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 ABK72139.1 - 3.9e-05 23.6 0.1 0.26 11.1 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ABK72139.1 - 7.8e-05 23.1 0.7 0.00017 22.0 0.7 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 ABK72139.1 - 0.0058 16.8 0.4 0.028 14.6 0.4 2.0 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ABK72139.1 - 0.0069 16.1 0.1 0.014 15.1 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ABK72139.1 - 0.0094 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase ABC_ATPase PF09818.9 ABK72139.1 - 0.048 12.5 0.2 6.3 5.5 0.1 2.7 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_25 PF13481.6 ABK72139.1 - 0.12 11.9 0.1 1.1 8.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 ABK72139.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Rad17 PF03215.15 ABK72139.1 - 0.15 12.0 0.2 0.44 10.4 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain NikR_C PF08753.11 ABK72139.1 - 0.16 12.2 0.4 2.6 8.3 0.1 2.3 2 0 0 2 2 2 0 NikR C terminal nickel binding domain AAA_24 PF13479.6 ABK72139.1 - 0.26 11.0 0.1 1.8 8.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain UDPGT PF00201.18 ABK72140.1 - 9.2e-08 31.3 0.0 2.5e-07 29.9 0.0 1.6 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 ABK72140.1 - 0.00012 22.2 0.0 0.00017 21.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 ABK72140.1 - 0.00042 19.7 0.0 0.0028 17.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 1 Glyco_transf_4 PF13439.6 ABK72140.1 - 0.014 15.4 0.3 0.11 12.5 0.1 2.5 2 1 0 2 2 2 0 Glycosyltransferase Family 4 Glyco_transf_28 PF03033.20 ABK72140.1 - 0.023 14.7 0.0 0.073 13.1 0.0 1.8 2 0 0 2 2 2 0 Glycosyltransferase family 28 N-terminal domain DUF2065 PF09838.9 ABK72140.1 - 0.07 13.2 3.4 0.098 12.7 1.2 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2065) Hydrolase_4 PF12146.8 ABK72141.1 - 1.3e-07 31.1 0.1 0.00063 19.1 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 ABK72141.1 - 6.6e-05 22.5 0.0 0.007 15.9 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 ABK72141.1 - 0.0049 16.5 0.0 2.1 7.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK72141.1 - 0.033 14.8 13.3 0.24 12.0 13.3 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Hexapep PF00132.24 ABK72142.1 - 1.2e-09 37.4 8.2 1.5e-07 30.9 0.4 3.5 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 ABK72142.1 - 0.027 14.2 5.2 0.88 9.4 0.3 3.3 3 1 1 4 4 4 0 Hexapeptide repeat of succinyl-transferase XFP_N PF09364.10 ABK72146.1 - 1e-183 610.2 0.0 1.3e-183 609.8 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 ABK72146.1 - 1.2e-91 305.6 0.0 3.2e-91 304.3 0.0 1.7 2 0 0 2 2 2 1 XFP C-terminal domain XFP PF03894.15 ABK72146.1 - 2.1e-89 297.9 0.0 3e-89 297.4 0.0 1.2 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.21 ABK72146.1 - 0.063 13.1 0.1 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DNA_pol3_delta2 PF13177.6 ABK72147.1 - 2.3e-37 128.3 0.0 3.3e-37 127.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DNA_pol3_gamma3 PF12169.8 ABK72147.1 - 8e-16 58.2 1.6 1.2e-15 57.6 1.6 1.3 1 0 0 1 1 1 1 DNA polymerase III subunits gamma and tau domain III AAA PF00004.29 ABK72147.1 - 3.5e-10 40.4 0.0 8.2e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ABK72147.1 - 1.1e-06 28.9 0.0 4e-05 23.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.12 ABK72147.1 - 2.3e-05 24.2 0.0 5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 ABK72147.1 - 0.00012 21.8 0.0 0.00036 20.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ABK72147.1 - 0.0015 18.9 7.1 0.0037 17.7 0.0 4.0 3 2 0 4 4 4 1 AAA ATPase domain AAA_19 PF13245.6 ABK72147.1 - 0.0052 17.1 0.0 0.037 14.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 ABK72147.1 - 0.0054 16.7 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_5 PF07728.14 ABK72147.1 - 0.01 15.8 0.0 5.1 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 ABK72147.1 - 0.014 14.8 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 ABK72147.1 - 0.086 12.9 0.0 0.52 10.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ABK72147.1 - 0.25 10.8 0.0 3.5 7.1 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region Acyl-CoA_dh_M PF02770.19 ABK72148.1 - 3.2e-23 81.7 0.0 5.2e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ABK72148.1 - 1.3e-17 64.5 0.1 2.7e-17 63.5 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 ABK72148.1 - 4.4e-09 36.7 3.5 1.2e-08 35.3 3.5 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 ABK72148.1 - 0.072 13.6 0.0 0.14 12.8 0.0 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal FAD_binding_3 PF01494.19 ABK72149.1 - 4e-81 273.0 0.0 5.3e-81 272.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 ABK72149.1 - 7.3e-05 22.1 0.2 0.00016 21.0 0.2 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 ABK72149.1 - 0.00024 21.6 0.2 0.019 15.5 0.4 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ABK72149.1 - 0.00047 19.5 1.2 0.018 14.3 0.3 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ABK72149.1 - 0.0073 16.5 1.3 0.013 15.7 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 ABK72149.1 - 0.011 14.9 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 ABK72149.1 - 0.012 14.9 0.0 0.038 13.2 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ABK72149.1 - 0.019 13.7 0.2 0.05 12.3 0.2 1.6 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 ABK72149.1 - 0.053 12.9 0.2 0.14 11.5 0.2 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase XdhC_C PF13478.6 ABK72149.1 - 0.086 13.4 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain DAO PF01266.24 ABK72149.1 - 0.093 12.3 4.7 0.23 11.0 1.8 2.3 1 1 0 2 2 2 0 FAD dependent oxidoreductase Hemerythrin PF01814.23 ABK72150.1 - 6.9e-14 52.6 4.0 1.1e-11 45.5 1.5 1.6 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain LSR PF05624.14 ABK72151.1 - 0.007 16.3 0.2 0.007 16.3 0.2 3.9 4 1 1 5 5 5 1 Lipolysis stimulated receptor (LSR) Phage_holin_3_6 PF07332.11 ABK72151.1 - 0.48 10.5 0.0 0.48 10.5 0.0 4.2 1 1 2 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III 7TMR-DISM_7TM PF07695.11 ABK72151.1 - 0.87 9.4 24.1 0.12 12.3 17.8 2.3 1 1 1 2 2 2 0 7TM diverse intracellular signalling NMO PF03060.15 ABK72152.1 - 6.8e-46 157.2 0.3 7.3e-45 153.8 0.3 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 ABK72152.1 - 4.5e-08 32.5 2.2 7.7e-08 31.7 2.2 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.14 ABK72152.1 - 0.00011 21.6 0.4 0.00017 21.0 0.4 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 ABK72152.1 - 0.00057 19.0 0.4 0.0014 17.7 0.4 1.8 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 ABK72152.1 - 0.17 11.3 1.5 0.19 11.2 0.5 1.6 2 0 0 2 2 2 0 Histidine biosynthesis protein PmbA_TldD PF01523.16 ABK72153.1 - 3.1e-52 178.1 0.2 4.2e-52 177.7 0.2 1.2 1 0 0 1 1 1 1 Putative modulator of DNA gyrase Fer2 PF00111.27 ABK72155.1 - 2.2e-13 49.9 0.1 5e-13 48.8 0.1 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FAD_binding_6 PF00970.24 ABK72155.1 - 8.9e-13 48.4 0.0 1.4e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 ABK72155.1 - 8e-12 45.8 0.0 3.6e-11 43.7 0.0 2.1 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain Fer2_3 PF13085.6 ABK72155.1 - 0.038 14.0 0.1 0.074 13.1 0.1 1.4 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain NAD_binding_6 PF08030.12 ABK72155.1 - 0.046 13.9 0.0 0.093 12.8 0.0 1.5 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Thiolase_N PF00108.23 ABK72156.1 - 4.8e-47 160.5 0.0 2e-43 148.6 0.0 2.3 2 0 0 2 2 2 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 ABK72156.1 - 5.2e-47 158.5 1.3 2e-46 156.6 0.1 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ABK72156.1 - 2.1e-05 24.2 0.2 6.9e-05 22.5 0.1 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 ABK72156.1 - 0.00072 19.7 0.0 0.0017 18.5 0.0 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal CoA_binding_2 PF13380.6 ABK72157.1 - 6.3e-37 126.6 0.0 7.4e-37 126.4 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 ABK72157.1 - 0.033 14.9 0.0 0.047 14.4 0.0 1.3 1 0 0 1 1 1 0 CoA binding domain HTH_AsnC-type PF13404.6 ABK72158.1 - 3.6e-16 58.7 2.1 1.6e-15 56.7 0.4 2.4 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 ABK72158.1 - 1.2e-14 53.6 0.0 2e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding AsnC_trans_reg PF01037.21 ABK72158.1 - 4e-14 52.3 0.1 5.9e-14 51.8 0.1 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain MarR_2 PF12802.7 ABK72158.1 - 0.00014 21.7 0.5 0.00028 20.7 0.1 1.7 2 0 0 2 2 2 1 MarR family Sigma70_r4 PF04545.16 ABK72158.1 - 0.023 14.2 0.8 0.048 13.2 0.0 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 MarR PF01047.22 ABK72158.1 - 0.025 14.5 0.0 0.061 13.3 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_23 PF13384.6 ABK72158.1 - 0.049 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain 4HBT PF03061.22 ABK72159.1 - 2.1e-16 60.0 0.2 2.9e-16 59.6 0.2 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 ABK72159.1 - 3e-08 34.2 0.0 3.6e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 ABK72159.1 - 0.0098 15.2 0.0 0.16 11.3 0.0 2.0 1 1 0 1 1 1 1 Acyl-ACP thioesterase DUF3039 PF11238.8 ABK72160.1 - 2.4e-29 100.8 0.3 2.9e-29 100.6 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3039) ADK_lid PF05191.14 ABK72160.1 - 0.024 14.6 0.3 0.39 10.8 0.1 2.4 2 0 0 2 2 2 0 Adenylate kinase, active site lid Fer4_15 PF13459.6 ABK72161.1 - 4.2e-13 49.8 2.5 5.1e-13 49.6 2.5 1.1 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_13 PF13370.6 ABK72161.1 - 1.8e-12 47.6 1.0 2e-12 47.5 1.0 1.0 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_19 PF06902.11 ABK72161.1 - 3.4e-08 33.4 0.0 3.6e-08 33.3 0.0 1.0 1 0 0 1 1 1 1 Divergent 4Fe-4S mono-cluster Fer4_6 PF12837.7 ABK72161.1 - 0.072 13.2 3.7 0.16 12.1 0.1 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4 PF00037.27 ABK72161.1 - 0.096 12.5 3.0 1.7 8.6 0.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain SDF PF00375.18 ABK72162.1 - 1.2e-106 357.0 36.0 1.4e-106 356.8 36.0 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family UNC45-central PF11701.8 ABK72162.1 - 0.12 12.3 1.5 0.21 11.5 0.6 1.7 1 1 0 1 1 1 0 Myosin-binding striated muscle assembly central UDPG_MGDP_dh_N PF03721.14 ABK72163.1 - 1.5e-35 122.5 0.0 2.8e-35 121.6 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 ABK72163.1 - 4.1e-27 94.2 0.0 7.6e-27 93.4 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 ABK72163.1 - 2.7e-12 47.0 0.0 3.3e-11 43.5 0.0 2.4 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.15 ABK72163.1 - 0.00012 22.2 0.2 0.0004 20.6 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 ABK72163.1 - 0.0019 17.9 0.0 0.01 15.5 0.0 2.0 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 ABK72163.1 - 0.0038 16.6 0.0 0.0069 15.8 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 ABK72163.1 - 0.014 15.2 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ABK72163.1 - 0.017 14.4 0.1 0.047 13.0 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 ABK72163.1 - 0.019 15.4 0.0 0.85 10.1 0.0 2.8 2 1 0 2 2 2 0 Putative NAD(P)-binding F420_oxidored PF03807.17 ABK72163.1 - 0.036 14.6 0.0 0.3 11.7 0.0 2.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.27 ABK72163.1 - 0.12 12.9 0.5 0.96 10.1 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Putative_PNPOx PF01243.20 ABK72164.1 - 3.4e-07 30.3 0.0 4.8e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF202 PF02656.15 ABK72165.1 - 2.7e-14 53.4 7.1 2.7e-14 53.4 7.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) G6PD_N PF00479.22 ABK72166.1 - 0.059 14.0 0.0 0.071 13.7 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain MSP1b PF03429.13 ABK72166.1 - 0.18 9.9 0.0 0.23 9.5 0.0 1.1 1 0 0 1 1 1 0 Major surface protein 1B FCD PF07729.12 ABK72167.1 - 2.2e-23 83.0 12.8 3.2e-23 82.5 12.8 1.2 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 ABK72167.1 - 1.3e-16 59.9 4.0 2.4e-15 55.9 0.0 2.9 3 0 0 3 3 3 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 ABK72167.1 - 0.011 15.3 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Fe_dep_repress PF01325.19 ABK72167.1 - 0.012 15.8 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_Crp_2 PF13545.6 ABK72167.1 - 0.016 15.2 0.0 0.063 13.3 0.0 2.0 1 1 1 2 2 2 0 Crp-like helix-turn-helix domain TrmB PF01978.19 ABK72167.1 - 0.023 14.6 0.0 0.056 13.3 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 ABK72167.1 - 0.074 12.9 2.8 0.1 12.4 0.0 2.6 4 0 0 4 4 4 0 IclR helix-turn-helix domain HTH_5 PF01022.20 ABK72167.1 - 0.091 12.6 0.0 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 ABK72167.1 - 0.26 11.2 0.1 0.26 11.2 0.1 2.6 3 0 0 3 3 3 0 MarR family PDGLE PF13190.6 ABK72168.1 - 2.3e-19 69.0 0.5 2.8e-19 68.8 0.5 1.1 1 0 0 1 1 1 1 PDGLE domain AtuA PF07287.11 ABK72169.1 - 3.4e-131 437.2 0.0 4.5e-131 436.7 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Gmad1 PF10647.9 ABK72170.1 - 3.6e-73 246.4 13.6 6.5e-73 245.6 13.6 1.4 1 0 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain Germane PF10646.9 ABK72170.1 - 6.6e-14 52.5 0.0 1.6e-13 51.3 0.0 1.7 1 0 0 1 1 1 1 Sporulation and spore germination LPAM_1 PF08139.12 ABK72170.1 - 0.49 11.0 1.9 1.1 9.9 1.9 1.6 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site HATPase_c PF02518.26 ABK72171.1 - 2.4e-22 79.6 0.0 4.5e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ABK72171.1 - 1.7e-17 63.2 1.0 5.3e-17 61.6 1.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 ABK72171.1 - 1.1e-06 28.9 0.1 3.9e-06 27.2 0.1 2.0 1 0 0 1 1 1 1 HAMP domain HATPase_c_3 PF13589.6 ABK72171.1 - 0.00023 21.0 0.0 0.0004 20.2 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF948 PF06103.11 ABK72171.1 - 0.021 15.1 0.6 0.091 13.0 0.6 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF2587 PF10759.9 ABK72171.1 - 0.068 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Usp PF00582.26 ABK72172.1 - 5.7e-16 59.3 0.4 1.3e-15 58.2 0.4 1.5 1 1 0 1 1 1 1 Universal stress protein family NMT1 PF09084.11 ABK72173.1 - 2.8e-30 105.9 0.0 3.7e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 ABK72173.1 - 1e-16 61.4 0.1 1.5e-16 60.9 0.1 1.2 1 0 0 1 1 1 1 NMT1-like family SBP_bac_3 PF00497.20 ABK72173.1 - 4e-07 29.7 0.0 1.1e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 ABK72173.1 - 0.0013 18.3 0.1 0.002 17.8 0.1 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_3 PF16868.5 ABK72173.1 - 0.029 13.8 0.0 0.041 13.3 0.0 1.2 1 0 0 1 1 1 0 NMT1-like family YhfZ_C PF14503.6 ABK72173.1 - 0.048 13.2 0.0 0.067 12.7 0.0 1.2 1 0 0 1 1 1 0 YhfZ C-terminal domain TetR_N PF00440.23 ABK72174.1 - 2e-13 49.9 0.0 3.5e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_31 PF17940.1 ABK72174.1 - 6.7e-05 23.1 0.5 0.00023 21.3 0.2 1.9 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_11 PF16859.5 ABK72174.1 - 0.00097 19.4 1.4 0.0049 17.2 0.6 2.1 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_20 PF17925.1 ABK72174.1 - 0.0027 18.0 0.0 0.007 16.7 0.0 1.8 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_6 PF13977.6 ABK72174.1 - 0.0082 16.4 0.6 0.016 15.4 0.3 1.7 1 1 0 1 1 1 1 BetI-type transcriptional repressor, C-terminal HTH_24 PF13412.6 ABK72174.1 - 0.19 11.3 0.0 0.38 10.3 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Amidohydro_1 PF01979.20 ABK72175.1 - 1.3e-26 93.8 2.1 2.5e-26 92.8 2.1 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ABK72175.1 - 1.5e-15 57.6 10.5 6.1e-12 45.8 4.1 2.6 1 1 1 2 2 2 2 Amidohydrolase family GHL6 PF14871.6 ABK72175.1 - 0.16 12.2 0.0 0.33 11.1 0.0 1.5 1 1 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 DEAD PF00270.29 ABK72176.1 - 1.2e-42 145.6 0.0 2.4e-42 144.7 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ABK72176.1 - 1.3e-23 83.4 0.1 3e-23 82.3 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ABK72176.1 - 1.1e-05 25.6 0.0 1.8e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 ABK72176.1 - 0.1 11.4 0.0 0.57 8.9 0.0 2.1 3 0 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Flavi_DEAD PF07652.14 ABK72176.1 - 0.15 12.1 0.5 2.3 8.2 0.1 2.9 2 2 0 2 2 2 0 Flavivirus DEAD domain AAA_22 PF13401.6 ABK72176.1 - 0.21 11.8 2.1 0.79 10.0 0.8 2.5 2 1 0 2 2 2 0 AAA domain PMT PF02366.18 ABK72177.1 - 2.4e-20 73.2 16.8 2e-16 60.3 9.2 3.3 2 1 1 3 3 3 2 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 ABK72177.1 - 1.1e-17 64.3 11.7 1.1e-17 64.3 11.7 3.6 3 2 0 3 3 3 2 C-terminal four TMM region of protein-O-mannosyltransferase PMT_2 PF13231.6 ABK72177.1 - 2.6e-08 34.3 0.5 2.6e-08 34.3 0.5 4.1 5 1 0 5 5 5 2 Dolichyl-phosphate-mannose-protein mannosyltransferase HA1 PF18239.1 ABK72177.1 - 0.074 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Hemagglutinin I ArAE_2_N PF10337.9 ABK72177.1 - 0.97 8.4 3.4 2 7.3 3.4 1.5 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal SBP_bac_5 PF00496.22 ABK72178.1 - 1.6e-16 60.3 0.0 2.8e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle TetR_N PF00440.23 ABK72179.1 - 1.4e-10 40.8 0.0 2.9e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 ABK72179.1 - 0.00014 22.0 3.1 0.00014 22.0 3.1 2.7 1 1 2 3 3 3 1 BetI-type transcriptional repressor, C-terminal TetR_C_31 PF17940.1 ABK72179.1 - 0.016 15.4 2.0 0.016 15.4 2.0 2.7 1 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HTH_23 PF13384.6 ABK72179.1 - 0.046 13.5 1.1 4.2 7.3 0.0 3.3 3 0 0 3 3 3 0 Homeodomain-like domain TetR_C_15 PF17918.1 ABK72179.1 - 0.54 11.0 6.5 2.3 9.0 1.2 2.4 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain AAA_3 PF07726.11 ABK72180.1 - 2.1e-59 199.0 0.0 4.1e-59 198.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 ABK72180.1 - 2.1e-19 69.2 0.5 4.5e-19 68.1 0.5 1.5 1 0 0 1 1 1 1 AAA lid domain AAA_5 PF07728.14 ABK72180.1 - 3.4e-15 56.3 0.0 6.8e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 ABK72180.1 - 0.0016 18.2 0.6 0.0089 15.7 0.0 2.2 3 0 0 3 3 3 1 Sigma-54 interaction domain MCM PF00493.23 ABK72180.1 - 0.0027 16.8 0.0 0.005 16.0 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain AAA PF00004.29 ABK72180.1 - 0.0043 17.5 0.0 0.011 16.2 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 ABK72180.1 - 0.074 12.8 0.1 1.6 8.5 0.2 2.7 2 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 ABK72180.1 - 0.077 12.4 0.4 2.4 7.5 0.1 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 ABK72180.1 - 0.12 12.7 0.3 0.65 10.3 0.1 2.1 2 1 0 2 2 2 0 AAA ATPase domain DUF1361 PF07099.11 ABK72181.1 - 5.6e-40 137.0 7.6 7.7e-40 136.6 7.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1361) HAD_2 PF13419.6 ABK72182.1 - 3.3e-18 66.4 0.0 4.1e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ABK72182.1 - 2.3e-15 57.4 1.0 1.1e-14 55.2 1.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ABK72182.1 - 1.4e-08 35.4 0.4 1.4e-08 35.4 0.4 1.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ABK72182.1 - 6.2e-08 32.6 0.1 1.5e-07 31.4 0.1 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 ABK72182.1 - 0.047 13.8 0.0 0.12 12.5 0.0 1.9 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Dyp_perox PF04261.12 ABK72183.1 - 3.1e-69 233.5 0.0 3.6e-69 233.2 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family TAT_signal PF10518.9 ABK72183.1 - 0.36 10.8 8.2 0.83 9.6 8.2 1.7 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence DUF4226 PF10774.9 ABK72184.1 - 0.0013 19.0 0.7 0.0013 19.0 0.7 2.6 4 0 0 4 4 4 1 Domain of unknown function (DUF4226) WXG100 PF06013.12 ABK72184.1 - 0.021 15.1 3.7 0.021 15.1 3.7 2.8 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DUF5082 PF16888.5 ABK72184.1 - 5.1 7.4 5.3 9.9 6.5 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) DHDPS PF00701.22 ABK72186.1 - 2.7e-77 259.4 0.0 3e-77 259.2 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family TetR_C_6 PF13977.6 ABK72186.1 - 0.0036 17.5 1.6 0.0088 16.3 0.2 2.1 2 0 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal Hexokinase_2 PF03727.16 ABK72186.1 - 0.052 13.0 0.0 0.071 12.5 0.0 1.1 1 0 0 1 1 1 0 Hexokinase AIRS_C PF02769.22 ABK72187.1 - 2e-26 93.0 1.0 3.5e-26 92.2 1.0 1.4 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 ABK72187.1 - 4.7e-16 59.2 4.7 4.7e-16 59.2 4.7 1.9 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain DUF2384 PF09722.10 ABK72188.1 - 0.12 12.5 0.1 0.12 12.5 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2384) DUF4381 PF14316.6 ABK72190.1 - 0.0021 18.3 0.3 0.0048 17.2 0.1 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4381) SopA PF13981.6 ABK72190.1 - 0.067 13.6 0.1 0.099 13.1 0.1 1.2 1 0 0 1 1 1 0 SopA-like central domain SnoaL_4 PF13577.6 ABK72190.1 - 0.21 11.7 1.7 0.17 12.0 0.3 1.6 2 0 0 2 2 2 0 SnoaL-like domain VirB8 PF04335.13 ABK72190.1 - 0.91 9.3 11.5 1.3 8.8 4.2 2.0 1 1 1 2 2 2 0 VirB8 protein adh_short PF00106.25 ABK72192.1 - 5.2e-50 169.6 0.5 7.7e-47 159.3 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase NAD_binding_4 PF07993.12 ABK72192.1 - 8.5e-45 152.9 0.1 2.1e-43 148.4 0.0 2.4 2 1 0 2 2 2 1 Male sterility protein adh_short_C2 PF13561.6 ABK72192.1 - 3.3e-34 118.5 2.8 5.7e-34 117.7 0.2 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ABK72192.1 - 1.1e-17 64.4 0.8 4.2e-13 49.3 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.10 ABK72192.1 - 4.7e-17 62.5 3.9 1.2e-12 48.2 0.3 2.5 2 1 0 2 2 2 2 KR domain 3Beta_HSD PF01073.19 ABK72192.1 - 3.8e-12 45.8 0.1 9.4e-12 44.5 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 ABK72192.1 - 3e-10 40.3 8.2 7.4e-06 26.0 1.0 2.6 2 0 0 2 2 2 2 NAD(P)H-binding RmlD_sub_bind PF04321.17 ABK72192.1 - 4.2e-10 39.2 1.8 3.2e-07 29.7 0.4 3.1 2 1 0 2 2 2 2 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 ABK72192.1 - 6.8e-09 35.6 0.1 1.4e-06 27.9 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ABK72192.1 - 5.8e-05 22.4 0.0 0.0021 17.2 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 ABK72192.1 - 0.0061 16.2 2.4 1.9 8.0 0.1 2.4 2 0 0 2 2 2 2 NmrA-like family Eno-Rase_NADH_b PF12242.8 ABK72192.1 - 0.033 14.0 0.3 0.071 12.9 0.3 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TetR_C_27 PF17935.1 ABK72192.1 - 0.037 14.1 0.7 4 7.5 0.1 2.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK72193.1 - 3.2e-10 39.6 0.0 7e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family Acyl-CoA_dh_1 PF00441.24 ABK72194.1 - 4.6e-24 85.3 5.6 8.2e-24 84.5 5.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 ABK72194.1 - 1.6e-08 34.9 4.7 3.6e-08 33.8 4.7 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK72194.1 - 3e-05 24.6 0.1 0.00011 22.9 0.1 2.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Dehydratase_LU PF02286.15 ABK72195.1 - 9.1e-260 863.0 0.1 1.1e-259 862.7 0.1 1.1 1 0 0 1 1 1 1 Dehydratase large subunit Dehydratase_MU PF02288.15 ABK72195.1 - 7.4e-27 93.4 0.0 1.7e-26 92.3 0.0 1.6 1 0 0 1 1 1 1 Dehydratase medium subunit FadR_C PF07840.12 ABK72195.1 - 0.24 11.3 0.0 0.46 10.4 0.0 1.4 1 0 0 1 1 1 0 FadR C-terminal domain OpuAC PF04069.12 ABK72196.1 - 6.5e-40 137.3 0.3 7.4e-40 137.2 0.3 1.0 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system MFS_1 PF07690.16 ABK72197.1 - 1.4e-34 119.5 73.7 4.9e-22 78.3 36.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldolase_II PF00596.21 ABK72198.1 - 1.7e-47 161.8 0.7 2.1e-47 161.5 0.7 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain HATPase_c PF02518.26 ABK72199.1 - 2.5e-21 76.2 0.0 4.4e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase cNMP_binding PF00027.29 ABK72199.1 - 7.1e-09 35.6 0.0 5e-08 32.9 0.0 2.2 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain HATPase_c_3 PF13589.6 ABK72199.1 - 0.0011 18.8 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 ABK72199.1 - 0.005 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 GHKL domain OPT PF03169.15 ABK72200.1 - 1.5e-104 350.9 51.3 1.9e-104 350.5 51.3 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Yip1 PF04893.17 ABK72200.1 - 0.0015 18.3 5.1 0.0015 18.3 5.1 6.3 3 2 1 4 4 4 1 Yip1 domain Condensation PF00668.20 ABK72201.1 - 6.5e-06 25.1 0.0 1.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Condensation domain AATase PF07247.12 ABK72201.1 - 0.21 10.1 0.0 2.4 6.6 0.0 2.5 3 0 0 3 3 3 0 Alcohol acetyltransferase Lactamase_B_2 PF12706.7 ABK72203.1 - 9.3e-05 22.0 0.5 0.00027 20.5 0.5 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ABK72203.1 - 0.014 15.4 1.1 0.028 14.5 1.0 1.7 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Pterin_4a PF01329.19 ABK72204.1 - 4.3e-27 94.1 0.0 4.7e-27 94.0 0.0 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase IF-2 PF11987.8 ABK72204.1 - 0.11 12.6 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Translation-initiation factor 2 3HCDH_N PF02737.18 ABK72206.1 - 5.1e-35 121.0 0.0 6.4e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 ABK72206.1 - 1.9e-14 54.0 0.0 4e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 2-Hacid_dh_C PF02826.19 ABK72206.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CbiA PF01656.23 ABK72206.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Glu_dehyd_C PF16912.5 ABK72206.1 - 0.2 11.1 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Trypan_PARP PF05887.11 ABK72207.1 - 0.31 11.0 12.8 0.65 10.0 12.8 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GlnD_UR_UTase PF08335.11 ABK72208.1 - 0.022 14.9 0.4 0.026 14.6 0.4 1.1 1 0 0 1 1 1 0 GlnD PII-uridylyltransferase NAD_Gly3P_dh_N PF01210.23 ABK72209.1 - 4e-52 176.3 0.1 6.3e-52 175.7 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 ABK72209.1 - 4.1e-50 169.8 1.7 6.2e-50 169.2 1.7 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus ApbA PF02558.16 ABK72209.1 - 2.1e-10 40.4 0.0 4.9e-10 39.3 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 ABK72209.1 - 9.9e-08 32.5 0.0 1.1e-06 29.2 0.0 2.5 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 ABK72209.1 - 7.9e-06 26.1 0.0 1.6e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 ABK72209.1 - 0.0031 17.4 0.0 0.0054 16.6 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 ABK72209.1 - 0.031 14.6 0.0 0.25 11.6 0.0 2.4 3 0 0 3 3 3 0 TrkA-N domain NAD_binding_10 PF13460.6 ABK72209.1 - 0.037 13.9 0.1 0.067 13.1 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H-binding 2-Hacid_dh_C PF02826.19 ABK72209.1 - 0.059 12.7 0.0 0.14 11.5 0.0 1.8 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 ABK72209.1 - 0.11 13.0 0.0 0.35 11.4 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase BPD_transp_2 PF02653.16 ABK72210.1 - 6.3e-36 123.9 33.2 7.3e-36 123.7 33.2 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component SnoaL_2 PF12680.7 ABK72211.1 - 1.4e-07 32.1 1.2 2.8e-07 31.1 1.2 1.7 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 ABK72211.1 - 1.1e-05 25.6 0.1 1.5e-05 25.2 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 ABK72211.1 - 0.033 14.0 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase DUF4440 PF14534.6 ABK72211.1 - 0.057 13.8 1.3 0.059 13.8 0.4 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4440) UvrD_C PF13361.6 ABK72212.1 - 1.5e-23 83.8 0.0 5.9e-14 52.2 0.0 2.1 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 ABK72212.1 - 1.8e-14 54.3 0.0 1.7e-13 51.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 ABK72212.1 - 7.5e-14 52.0 0.0 1.4e-06 28.0 0.0 2.2 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 ABK72212.1 - 3.5e-07 29.9 0.3 3.4e-06 26.8 0.3 2.5 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 ABK72212.1 - 0.00037 20.3 0.1 0.0032 17.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 ABK72212.1 - 0.0012 18.1 0.1 0.014 14.6 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 ABK72212.1 - 0.0025 18.1 0.4 0.73 10.1 0.1 3.0 2 1 0 2 2 2 1 AAA domain PhoH PF02562.16 ABK72212.1 - 0.0031 17.0 0.0 0.11 12.0 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein ResIII PF04851.15 ABK72212.1 - 0.057 13.4 0.0 0.18 11.8 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 ABK72212.1 - 0.059 13.1 0.1 1.8 8.3 0.0 2.9 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 ABK72212.1 - 0.071 13.5 3.5 2.9 8.2 3.5 2.6 1 1 0 1 1 1 0 AAA ATPase domain Transp_cyt_pur PF02133.15 ABK72213.1 - 2e-51 175.1 35.8 2.3e-51 175.0 35.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin His_biosynth PF00977.21 ABK72214.1 - 3.2e-62 210.0 1.1 3.7e-62 209.8 1.1 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.17 ABK72214.1 - 1.5e-05 24.3 0.0 0.011 14.9 0.0 2.2 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NMO PF03060.15 ABK72214.1 - 7.7e-05 22.2 4.9 0.017 14.5 0.1 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase Sacchrp_dh_NADP PF03435.18 ABK72214.1 - 0.013 15.7 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Aconitase_C PF00694.19 ABK72214.1 - 0.034 14.5 0.0 0.053 13.9 0.0 1.2 1 0 0 1 1 1 0 Aconitase C-terminal domain Radical_SAM PF04055.21 ABK72214.1 - 0.12 12.7 0.0 5.6 7.3 0.0 2.6 1 1 0 1 1 1 0 Radical SAM superfamily MDMPI_C PF07398.11 ABK72214.1 - 0.71 10.8 11.9 0.06 14.2 5.3 2.4 2 1 1 3 3 3 0 MDMPI C-terminal domain Fumerase PF05681.14 ABK72215.1 - 5.1e-81 272.0 0.0 6.8e-81 271.6 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Fumerase_C PF05683.12 ABK72215.1 - 1.6e-77 259.5 0.0 2.3e-77 259.0 0.0 1.2 1 0 0 1 1 1 1 Fumarase C-terminus HTH_5 PF01022.20 ABK72216.1 - 9.3e-15 54.2 0.0 1.4e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 ABK72216.1 - 4.4e-11 42.7 2.4 6.3e-11 42.2 0.7 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 ABK72216.1 - 6e-05 22.9 0.1 9.3e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 ABK72216.1 - 7.9e-05 22.5 0.1 0.0001 22.1 0.1 1.3 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 ABK72216.1 - 0.00038 20.7 0.0 0.00056 20.2 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator Fe_dep_repress PF01325.19 ABK72216.1 - 0.00089 19.4 0.0 0.0012 19.0 0.0 1.2 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_IclR PF09339.10 ABK72216.1 - 0.0012 18.6 0.2 0.0024 17.6 0.2 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_24 PF13412.6 ABK72216.1 - 0.0016 18.0 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 ABK72216.1 - 0.0019 18.1 0.0 0.0026 17.6 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR PF01047.22 ABK72216.1 - 0.0043 17.0 0.0 0.007 16.3 0.0 1.3 1 0 0 1 1 1 1 MarR family RP-C PF03428.13 ABK72216.1 - 0.013 15.2 0.1 0.02 14.6 0.1 1.2 1 0 0 1 1 1 0 Replication protein C N-terminal domain LexA_DNA_bind PF01726.16 ABK72216.1 - 0.068 13.0 0.4 0.23 11.3 0.1 1.8 2 0 0 2 2 2 0 LexA DNA binding domain HTH_40 PF14493.6 ABK72216.1 - 0.084 13.3 0.0 0.11 13.0 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_34 PF13601.6 ABK72216.1 - 0.12 12.6 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain PaaX PF07848.12 ABK72216.1 - 0.14 12.4 0.1 0.21 11.9 0.1 1.2 1 0 0 1 1 1 0 PaaX-like protein HTH_11 PF08279.12 ABK72216.1 - 0.14 12.1 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 HTH domain HTH_27 PF13463.6 ABK72216.1 - 0.15 12.5 0.1 0.37 11.3 0.1 1.6 1 1 1 2 2 2 0 Winged helix DNA-binding domain HTH_36 PF13730.6 ABK72216.1 - 0.19 11.7 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain COX4_pro PF03626.14 ABK72217.1 - 1.1e-11 45.0 12.9 1.3e-11 44.7 12.9 1.2 1 0 0 1 1 1 1 Prokaryotic Cytochrome C oxidase subunit IV AMP-binding PF00501.28 ABK72218.1 - 2.7e-79 266.7 0.0 3.6e-79 266.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK72218.1 - 6.9e-05 23.8 0.8 0.00046 21.1 0.5 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF4193 PF13834.6 ABK72219.1 - 5.8e-46 155.0 3.2 6.5e-46 154.8 3.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4193) ArfGap PF01412.18 ABK72219.1 - 0.014 15.5 0.6 0.12 12.5 0.3 2.0 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf MlaE PF02405.16 ABK72220.1 - 1.3e-60 204.7 20.8 1.6e-60 204.5 20.8 1.0 1 0 0 1 1 1 1 Permease MlaE HTH_1 PF00126.27 ABK72221.1 - 3e-21 75.1 3.8 7.6e-21 73.8 3.8 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 ABK72221.1 - 3.9e-19 68.8 6.4 5.9e-19 68.3 6.4 1.2 1 0 0 1 1 1 1 LysR substrate binding domain AAA_2 PF07724.14 ABK72222.1 - 8.1e-52 175.8 0.4 2.3e-50 171.0 0.0 2.8 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 ABK72222.1 - 4.6e-36 122.9 4.8 6.5e-36 122.4 0.8 2.4 2 0 0 2 2 2 1 AAA lid domain Clp_N PF02861.20 ABK72222.1 - 3.5e-27 94.3 0.7 3.4e-13 49.5 0.1 3.1 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component ClpB_D2-small PF10431.9 ABK72222.1 - 8e-26 89.9 0.1 3.1e-25 88.0 0.1 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 ABK72222.1 - 8.6e-25 87.7 2.1 1.7e-12 47.9 0.0 4.3 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ABK72222.1 - 7e-18 65.0 1.1 2.6e-12 46.9 0.0 4.2 3 2 1 4 4 4 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ABK72222.1 - 1.9e-10 41.4 15.0 3.4e-06 27.5 0.1 4.9 4 3 1 6 6 4 2 AAA ATPase domain Sigma54_activat PF00158.26 ABK72222.1 - 2.3e-08 33.9 0.0 1e-05 25.3 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 ABK72222.1 - 6e-08 33.1 3.7 0.035 14.4 0.0 5.3 4 2 1 5 5 5 2 AAA domain IstB_IS21 PF01695.17 ABK72222.1 - 9e-07 28.8 0.0 0.048 13.4 0.0 2.9 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_14 PF13173.6 ABK72222.1 - 1e-05 25.6 0.0 0.17 11.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain ATPase_2 PF01637.18 ABK72222.1 - 1.2e-05 25.4 5.2 0.47 10.3 0.0 4.3 5 0 0 5 5 4 2 ATPase domain predominantly from Archaea AAA_23 PF13476.6 ABK72222.1 - 1.4e-05 25.7 5.5 0.78 10.2 4.5 3.5 3 1 0 3 3 3 2 AAA domain Mg_chelatase PF01078.21 ABK72222.1 - 1.6e-05 24.4 0.0 0.29 10.5 0.0 3.4 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 ABK72222.1 - 3.9e-05 23.2 0.2 0.26 10.7 0.0 3.8 3 1 1 4 4 3 1 Bacterial TniB protein AAA_7 PF12775.7 ABK72222.1 - 5.3e-05 22.8 0.0 0.1 12.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 ABK72222.1 - 6.2e-05 23.6 2.1 0.16 12.5 0.0 3.8 4 1 1 5 5 3 1 AAA domain AAA_24 PF13479.6 ABK72222.1 - 8.7e-05 22.3 0.1 0.65 9.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_3 PF07726.11 ABK72222.1 - 0.00015 21.7 0.1 0.66 9.8 0.0 3.8 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 ABK72222.1 - 0.0002 21.6 0.2 0.94 9.7 0.0 3.3 3 0 0 3 3 2 2 AAA domain Roc PF08477.13 ABK72222.1 - 0.00024 21.3 0.0 0.68 10.2 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 ABK72222.1 - 0.00026 21.0 0.0 0.073 13.0 0.0 2.7 2 0 0 2 2 2 1 NACHT domain TsaE PF02367.17 ABK72222.1 - 0.00046 20.2 0.0 1.4 9.0 0.0 3.2 4 0 0 4 4 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 ABK72222.1 - 0.00064 20.1 0.0 1.6 9.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase RsgA_GTPase PF03193.16 ABK72222.1 - 0.001 19.0 0.0 1.7 8.5 0.0 2.7 3 0 0 3 3 2 1 RsgA GTPase AAA_33 PF13671.6 ABK72222.1 - 0.0012 19.0 0.0 1.4 9.1 0.0 3.3 3 0 0 3 3 2 1 AAA domain NYD-SP28 PF14772.6 ABK72222.1 - 0.0068 16.4 10.3 0.019 15.0 10.3 1.8 1 0 0 1 1 1 1 Sperm tail ABC_tran PF00005.27 ABK72222.1 - 0.0071 16.9 0.1 1.6 9.2 0.0 3.0 3 0 0 3 3 2 1 ABC transporter Zeta_toxin PF06414.12 ABK72222.1 - 0.0077 15.5 0.8 0.82 8.9 0.0 3.2 3 1 0 3 3 3 1 Zeta toxin AAA_25 PF13481.6 ABK72222.1 - 0.014 15.0 0.1 1.2 8.6 0.0 3.0 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 ABK72222.1 - 0.018 14.8 5.0 3 7.6 0.0 4.4 4 1 0 4 4 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 ABK72222.1 - 0.018 14.8 0.0 11 5.8 0.0 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain T2SSE PF00437.20 ABK72222.1 - 0.021 13.9 0.0 0.053 12.6 0.0 1.8 1 1 0 1 1 1 0 Type II/IV secretion system protein MAD PF05557.13 ABK72222.1 - 0.022 13.1 7.0 0.037 12.4 7.0 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein AAA_30 PF13604.6 ABK72222.1 - 0.022 14.5 0.1 5.9 6.6 0.0 3.4 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 ABK72222.1 - 0.027 13.6 0.0 3.2 6.8 0.0 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF815) FTA4 PF13093.6 ABK72222.1 - 0.039 13.8 2.7 0.072 13.0 2.7 1.4 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 AAA_19 PF13245.6 ABK72222.1 - 0.04 14.2 0.0 1.6 9.1 0.0 3.0 2 0 0 2 2 2 0 AAA domain DNA_pol3_delta2 PF13177.6 ABK72222.1 - 0.053 13.3 0.0 0.28 11.0 0.0 2.1 1 1 0 1 1 1 0 DNA polymerase III, delta subunit NTPase_1 PF03266.15 ABK72222.1 - 0.061 13.2 0.0 7.9 6.4 0.0 2.7 2 0 0 2 2 2 0 NTPase SRP54 PF00448.22 ABK72222.1 - 0.08 12.6 0.0 2.8 7.5 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain EcoEI_R_C PF08463.10 ABK72222.1 - 0.11 12.6 2.2 0.38 10.8 1.9 2.1 2 0 0 2 2 1 0 EcoEI R protein C-terminal ResIII PF04851.15 ABK72222.1 - 0.12 12.4 0.0 3.9 7.4 0.0 2.8 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit Fez1 PF06818.15 ABK72222.1 - 0.13 12.7 6.9 0.29 11.6 6.9 1.5 1 0 0 1 1 1 0 Fez1 DUF87 PF01935.17 ABK72222.1 - 0.17 12.0 3.3 8.9 6.3 0.0 3.8 4 0 0 4 4 4 0 Helicase HerA, central domain ATP_bind_1 PF03029.17 ABK72222.1 - 0.18 11.6 0.0 7.7 6.2 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 ABK72222.1 - 0.18 11.5 0.0 2.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF4407 PF14362.6 ABK72222.1 - 0.59 9.4 4.6 1.2 8.5 4.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_13 PF13166.6 ABK72222.1 - 0.95 8.0 4.1 1.6 7.3 4.1 1.2 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.11 ABK72222.1 - 1.8 7.4 9.2 3.1 6.6 9.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein TPP_enzyme_N PF02776.18 ABK72223.1 - 1.8e-46 157.9 0.5 2e-42 144.7 0.0 2.2 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 ABK72223.1 - 4.2e-29 101.3 0.0 1.2e-28 99.8 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 ABK72223.1 - 4.1e-24 84.9 0.0 7.9e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain E1_dh PF00676.20 ABK72223.1 - 0.00027 20.0 0.0 0.00049 19.1 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 ABK72223.1 - 0.035 13.3 0.0 0.066 12.4 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Bac_luciferase PF00296.20 ABK72224.1 - 6.1e-53 180.3 2.5 7.5e-53 180.0 2.5 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase CdhD PF03599.16 ABK72224.1 - 0.07 11.8 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit tRNA-synt_2d PF01409.20 ABK72224.1 - 0.089 12.3 0.0 12 5.3 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) FAA_hydrolase PF01557.18 ABK72225.1 - 3.6e-54 183.7 0.1 4.2e-54 183.5 0.1 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family SnoaL_3 PF13474.6 ABK72226.1 - 4.6e-05 23.7 0.0 8.3e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 ABK72226.1 - 0.014 15.8 0.2 0.03 14.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) Aconitase_C PF00694.19 ABK72227.1 - 1.6e-08 34.9 0.0 2.5e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain AP_endonuc_2 PF01261.24 ABK72228.1 - 1.3e-28 99.9 0.3 2.8e-28 98.8 0.4 1.4 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel ChuX_HutX PF06228.13 ABK72228.1 - 0.018 14.8 0.1 0.49 10.2 0.0 2.6 3 0 0 3 3 3 0 Haem utilisation ChuX/HutX Sugar_tr PF00083.24 ABK72230.1 - 1.8e-29 102.9 27.6 1.1e-28 100.3 27.5 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ABK72230.1 - 4.6e-29 101.4 55.5 1.2e-20 73.7 21.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ABK72230.1 - 5.4e-05 21.9 37.2 0.0002 20.1 14.9 3.4 1 1 1 3 3 3 2 MFS/sugar transport protein Ldr_toxin PF13940.6 ABK72230.1 - 5.7 7.1 7.2 17 5.6 0.0 4.0 2 1 1 3 3 3 0 Toxin Ldr, type I toxin-antitoxin system Mqo PF06039.15 ABK72231.1 - 1e-223 743.3 0.0 1.1e-223 743.1 0.0 1.0 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) DAO PF01266.24 ABK72231.1 - 1.8e-07 31.1 0.0 2.6e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ABK72231.1 - 0.013 14.8 0.0 0.044 13.0 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain HTH_30 PF13556.6 ABK72234.1 - 8.9e-16 57.4 0.0 2.1e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_1 PF00126.27 ABK72234.1 - 0.038 13.9 0.0 0.17 11.9 0.0 2.1 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family RHH_4 PF13467.6 ABK72234.1 - 0.08 12.8 2.1 2 8.4 0.0 3.5 3 1 1 4 4 4 0 Ribbon-helix-helix domain EutB PF06751.11 ABK72235.1 - 5.3e-208 691.2 0.0 6e-208 691.0 0.0 1.0 1 0 0 1 1 1 1 Ethanolamine ammonia lyase large subunit (EutB) NTP_transferase PF00483.23 ABK72236.1 - 4.2e-59 200.1 0.0 5.2e-59 199.8 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 ABK72236.1 - 1.5e-10 41.7 0.0 1.8e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 ABK72236.1 - 0.013 15.3 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase PS_pyruv_trans PF04230.13 ABK72237.1 - 2.5e-21 76.9 0.0 3.5e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide pyruvyl transferase Transpeptidase PF00905.22 ABK72238.1 - 3.2e-41 141.5 0.0 4.6e-41 141.0 0.0 1.2 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain MecA_N PF05223.11 ABK72238.1 - 5.1e-06 26.8 0.0 8.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 NTF2-like N-terminal transpeptidase domain F420_ligase PF01996.16 ABK72238.1 - 0.11 11.8 0.0 0.35 10.2 0.0 1.8 2 0 0 2 2 2 0 F420-0:Gamma-glutamyl ligase TadE PF07811.12 ABK72239.1 - 0.0052 17.0 6.2 0.011 16.0 6.2 1.6 1 0 0 1 1 1 1 TadE-like protein GHMP_kinases_N PF00288.26 ABK72239.1 - 0.22 11.8 4.5 0.45 10.8 4.5 1.5 1 0 0 1 1 1 0 GHMP kinases N terminal domain MFS_1 PF07690.16 ABK72240.1 - 2.3e-59 201.1 56.3 3.6e-56 190.6 35.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK72240.1 - 8.4e-05 21.6 25.6 0.012 14.5 14.5 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter DUF3464 PF11947.8 ABK72240.1 - 1.5 8.6 3.5 2.5 7.8 2.6 1.9 1 1 0 1 1 1 0 Photosynthesis affected mutant 68 ABC_tran PF00005.27 ABK72241.1 - 1.2e-30 106.8 0.0 2.3e-30 105.9 0.0 1.5 2 0 0 2 2 1 1 ABC transporter TOBE_2 PF08402.10 ABK72241.1 - 9.6e-08 32.1 0.3 2.7e-07 30.6 0.1 1.9 2 0 0 2 2 1 1 TOBE domain OB_MalK PF17912.1 ABK72241.1 - 5e-06 27.2 1.7 3e-05 24.8 1.7 2.4 1 1 0 1 1 1 1 MalK OB fold domain AAA_21 PF13304.6 ABK72241.1 - 3.4e-05 23.8 0.0 0.012 15.4 0.0 2.5 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system CysA_C_terminal PF17850.1 ABK72241.1 - 9.9e-05 22.8 0.8 0.0008 19.9 0.2 2.5 2 0 0 2 2 2 1 CysA C-terminal regulatory domain Rad17 PF03215.15 ABK72241.1 - 0.00014 21.9 0.0 0.0002 21.3 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 ABK72241.1 - 0.0019 18.6 0.2 0.0033 17.8 0.2 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ABK72241.1 - 0.002 18.4 0.1 0.0034 17.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 ABK72241.1 - 0.0029 17.1 0.0 0.026 14.0 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 ABK72241.1 - 0.0039 17.1 0.0 0.0069 16.3 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase TOBE PF03459.17 ABK72241.1 - 0.0051 17.1 0.0 0.024 14.9 0.0 2.2 1 0 0 1 1 1 1 TOBE domain AAA PF00004.29 ABK72241.1 - 0.017 15.6 0.0 0.031 14.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 ABK72241.1 - 0.022 14.1 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 ABK72241.1 - 0.042 13.4 0.1 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ABK72241.1 - 0.042 14.0 0.1 0.09 12.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ABK72241.1 - 0.052 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 ABK72241.1 - 0.054 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 ABK72241.1 - 0.075 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.14 ABK72241.1 - 0.15 12.1 0.1 0.3 11.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 ABK72241.1 - 0.15 12.3 0.2 4.9 7.5 0.1 2.6 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 ABK72241.1 - 0.17 12.1 0.1 0.36 11.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain Acetyltransf_6 PF13480.7 ABK72242.1 - 9.8e-25 87.4 5.4 1e-23 84.1 0.5 3.3 4 0 0 4 4 4 1 Acetyltransferase (GNAT) domain Glycos_transf_2 PF00535.26 ABK72242.1 - 1.1e-11 44.8 0.0 3.2e-11 43.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ABK72242.1 - 6.7e-06 26.2 0.0 1.3e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 ABK72242.1 - 0.019 15.4 0.0 0.089 13.3 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 2 FemAB_like PF04339.12 ABK72242.1 - 0.097 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Peptidogalycan biosysnthesis/recognition RDD PF06271.12 ABK72243.1 - 3.5e-26 92.1 3.6 4.2e-26 91.8 3.6 1.1 1 0 0 1 1 1 1 RDD family DUF5336 PF17270.2 ABK72243.1 - 0.22 11.1 0.1 0.22 11.1 0.1 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5336) DUF3810 PF12725.7 ABK72243.1 - 0.3 10.4 0.1 0.33 10.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) TrbE PF11100.8 ABK72243.1 - 0.33 11.2 4.3 2.1 8.6 0.1 2.8 3 0 0 3 3 3 0 Conjugal transfer protein TrbE 2-Hacid_dh_C PF02826.19 ABK72244.1 - 1.1e-47 161.7 0.0 1.8e-47 161.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ABK72244.1 - 9.5e-22 77.1 0.1 1.2e-21 76.8 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ABK72244.1 - 5.2e-06 26.7 0.0 9.2e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.21 ABK72244.1 - 0.011 15.0 0.1 0.026 13.9 0.0 1.6 2 0 0 2 2 2 0 ThiF family F420_oxidored PF03807.17 ABK72244.1 - 0.058 14.0 4.4 0.11 13.1 2.1 2.5 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 ABK72245.1 - 3.6e-42 144.2 0.1 5.9e-42 143.5 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ABK72245.1 - 7.9e-13 48.7 2.3 1.5e-12 47.9 2.3 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 ABK72245.1 - 3.6e-07 30.7 1.4 6.6e-06 26.6 0.0 3.0 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 ABK72245.1 - 6.8e-05 22.3 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 ABK72245.1 - 0.015 14.9 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_Gly3P_dh_N PF01210.23 ABK72245.1 - 0.054 13.5 0.0 0.15 12.0 0.0 1.9 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 ABK72245.1 - 0.061 13.2 0.0 2.9 7.7 0.0 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 ABK72245.1 - 0.12 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF166 PF02593.14 ABK72245.1 - 0.17 11.4 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function HTH_20 PF12840.7 ABK72245.1 - 0.6 10.2 3.9 10 6.3 0.1 3.3 4 0 0 4 4 4 0 Helix-turn-helix domain HD PF01966.22 ABK72246.1 - 1.3e-21 77.1 0.0 2.3e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 HD domain HD_assoc PF13286.6 ABK72246.1 - 1.2e-16 61.1 0.2 2.5e-16 60.0 0.2 1.6 1 0 0 1 1 1 1 Phosphohydrolase-associated domain HDOD PF08668.12 ABK72246.1 - 0.022 14.2 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 HDOD domain FCD PF07729.12 ABK72248.1 - 6e-24 84.9 7.7 8.7e-24 84.3 7.7 1.2 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 ABK72248.1 - 3.4e-15 55.4 0.0 7.2e-15 54.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 ABK72248.1 - 0.00021 20.8 0.0 0.00052 19.5 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 ABK72248.1 - 0.0086 16.0 0.1 0.03 14.3 0.0 2.0 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_IclR PF09339.10 ABK72248.1 - 0.047 13.5 0.2 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_11 PF08279.12 ABK72248.1 - 0.052 13.5 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 HTH domain HTH_AsnC-type PF13404.6 ABK72248.1 - 0.066 13.1 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Rrf2 PF02082.20 ABK72248.1 - 0.11 12.9 0.0 0.44 10.9 0.0 2.0 1 0 0 1 1 1 0 Transcriptional regulator Fur_reg_FbpA PF13076.6 ABK72248.1 - 1.2 8.9 4.1 11 5.8 0.0 2.5 2 0 0 2 2 2 0 Fur-regulated basic protein A DUF308 PF03729.13 ABK72249.1 - 0.55 10.6 14.6 2.8 8.3 5.1 2.5 1 1 2 3 3 3 0 Short repeat of unknown function (DUF308) Sugar_tr PF00083.24 ABK72251.1 - 3.7e-38 131.6 22.3 9.6e-36 123.6 22.3 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ABK72251.1 - 5.3e-31 107.8 53.1 1.3e-24 86.8 30.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily AzlD PF05437.12 ABK72251.1 - 0.002 18.2 13.2 0.13 12.4 0.2 4.0 4 0 0 4 4 4 2 Branched-chain amino acid transport protein (AzlD) DUF3792 PF12670.7 ABK72251.1 - 0.015 15.4 27.1 0.11 12.7 0.7 4.3 3 1 1 4 4 4 0 Protein of unknown function (DUF3792) DUF1129 PF06570.11 ABK72251.1 - 1.4 8.3 14.9 0.031 13.8 1.5 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1129) Peptidase_U4 PF03419.13 ABK72251.1 - 8.8 5.5 21.8 5.1 6.3 5.0 3.1 1 1 2 3 3 3 0 Sporulation factor SpoIIGA Acyl-CoA_dh_1 PF00441.24 ABK72252.1 - 1.5e-29 103.1 2.9 2.7e-29 102.3 2.9 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK72252.1 - 4.7e-15 56.2 0.8 1.4e-14 54.7 0.2 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ABK72252.1 - 2.6e-07 31.0 3.0 2.6e-07 31.0 3.0 2.7 2 1 1 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain ECH_1 PF00378.20 ABK72253.1 - 5.6e-52 176.5 0.0 6.6e-52 176.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK72253.1 - 3.3e-28 99.1 0.0 4e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK72254.1 - 2.8e-122 408.4 0.0 3.1e-122 408.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 ABK72254.1 - 2.9e-35 121.8 0.4 1.2e-32 113.2 0.1 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase UDPG_MGDP_dh PF00984.19 ABK72254.1 - 0.13 12.5 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain DJ-1_PfpI PF01965.24 ABK72255.1 - 1.2e-31 109.8 0.2 1.8e-31 109.2 0.2 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family HTH_18 PF12833.7 ABK72255.1 - 1.3e-21 76.6 0.5 3.4e-21 75.3 0.5 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 ABK72255.1 - 1.5e-13 50.4 0.0 1.2e-06 28.4 0.0 2.6 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_28 PF13518.6 ABK72255.1 - 0.00083 19.4 0.3 0.055 13.6 0.0 2.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 ABK72255.1 - 0.00092 19.5 0.5 0.0047 17.2 0.0 2.4 3 0 0 3 3 3 1 Transposase Replic_Relax PF13814.6 ABK72255.1 - 0.012 15.7 0.0 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Replication-relaxation Acetyltransf_3 PF13302.7 ABK72256.1 - 2.9e-19 70.1 0.0 3.4e-19 69.9 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ABK72256.1 - 0.0005 20.2 0.0 0.00059 20.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ABK72256.1 - 0.0022 18.2 0.0 0.0027 17.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 ABK72256.1 - 0.1 12.6 0.1 0.19 11.7 0.1 1.5 1 1 0 1 1 1 0 FR47-like protein SfLAP PF11139.8 ABK72257.1 - 5.2e-63 212.3 25.9 5.9e-63 212.2 25.9 1.0 1 0 0 1 1 1 1 Sap, sulfolipid-1-addressing protein NMO PF03060.15 ABK72258.1 - 2.1e-47 162.1 1.3 3.5e-47 161.4 1.3 1.3 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 ABK72258.1 - 4.4e-06 26.0 4.8 7.1e-06 25.3 4.8 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 ABK72258.1 - 1.8e-05 23.9 0.0 0.0015 17.6 2.8 2.0 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain PEP_hydrolase PF09370.10 ABK72258.1 - 0.026 13.7 0.5 0.044 13.0 0.5 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like Glu_synthase PF01645.17 ABK72258.1 - 0.3 10.2 5.4 0.65 9.1 5.4 1.5 1 1 0 1 1 1 0 Conserved region in glutamate synthase AMP-binding PF00501.28 ABK72259.1 - 3.7e-65 220.2 0.0 5.2e-65 219.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK72259.1 - 1.1e-23 84.0 0.1 3.2e-23 82.5 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 ABK72259.1 - 0.077 13.3 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Bac_luciferase PF00296.20 ABK72261.1 - 3.8e-48 164.5 3.7 1.1e-47 163.0 3.4 1.6 1 1 1 2 2 2 2 Luciferase-like monooxygenase EcKinase PF02958.20 ABK72262.1 - 1.4e-25 90.3 0.0 4.5e-25 88.6 0.0 1.8 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 ABK72262.1 - 1.7e-17 64.2 3.7 3.2e-17 63.3 3.7 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 ABK72262.1 - 8.1e-07 28.2 0.0 1.2e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) PilX PF13681.6 ABK72262.1 - 2.5 8.5 4.1 30 5.1 0.0 3.2 4 0 0 4 4 4 0 Type IV pilus assembly protein PilX C-term Fer4_15 PF13459.6 ABK72264.1 - 1.2e-15 58.0 3.9 1.4e-15 57.7 3.9 1.0 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_13 PF13370.6 ABK72264.1 - 2.3e-14 53.6 1.7 2.8e-14 53.4 1.7 1.0 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_19 PF06902.11 ABK72264.1 - 4.5e-06 26.6 0.1 5.5e-06 26.4 0.1 1.1 1 0 0 1 1 1 1 Divergent 4Fe-4S mono-cluster ADH_N PF08240.12 ABK72265.1 - 5.3e-33 113.2 1.2 5.3e-33 113.2 1.2 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ABK72265.1 - 1.2e-20 73.8 0.8 2e-20 73.1 0.3 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ABK72265.1 - 4.6e-08 34.2 0.6 2.5e-07 31.8 0.1 2.3 3 0 0 3 3 3 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 ABK72265.1 - 0.00026 21.3 1.7 0.0012 19.1 0.5 2.2 2 0 0 2 2 2 1 TrkA-N domain Shikimate_DH PF01488.20 ABK72265.1 - 0.003 17.6 0.1 0.0062 16.6 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Glu_dehyd_C PF16912.5 ABK72265.1 - 0.0048 16.4 1.0 0.011 15.2 0.9 1.8 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 ABK72265.1 - 0.039 13.2 0.6 0.066 12.5 0.6 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 ABK72265.1 - 0.044 13.1 0.1 0.081 12.3 0.1 1.3 1 0 0 1 1 1 0 ThiF family MTS PF05175.14 ABK72265.1 - 0.045 13.3 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 ABK72265.1 - 0.053 13.3 0.1 0.13 12.0 0.1 1.6 2 0 0 2 2 2 0 Methyltransferase domain Sacchrp_dh_NADP PF03435.18 ABK72265.1 - 0.089 13.1 0.5 0.22 11.8 0.5 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain PglD_N PF17836.1 ABK72265.1 - 0.91 10.2 4.7 0.91 10.2 0.8 2.5 1 1 0 2 2 2 0 PglD N-terminal domain adh_short PF00106.25 ABK72266.1 - 4.3e-19 68.7 0.3 2.1e-18 66.5 0.9 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK72266.1 - 3.5e-13 49.7 0.2 5.4e-13 49.0 0.2 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ABK72266.1 - 0.00012 21.7 0.0 0.00017 21.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 ABK72266.1 - 0.00026 21.0 0.8 0.00043 20.2 0.8 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ABK72266.1 - 0.013 15.4 2.2 0.02 14.8 2.2 1.3 1 0 0 1 1 1 0 NAD(P)H-binding NmrA PF05368.13 ABK72266.1 - 0.041 13.4 1.3 0.077 12.5 1.3 1.5 1 0 0 1 1 1 0 NmrA-like family PHP_C PF13263.6 ABK72266.1 - 0.043 13.6 0.1 5.7 6.8 0.0 2.7 2 0 0 2 2 2 0 PHP-associated RmlD_sub_bind PF04321.17 ABK72266.1 - 0.11 11.6 0.2 0.54 9.3 0.2 1.9 1 1 0 1 1 1 0 RmlD substrate binding domain Sel_put PF04328.13 ABK72267.1 - 1e-23 83.1 3.4 1.2e-23 82.9 3.4 1.0 1 0 0 1 1 1 1 Selenoprotein, putative Condensation PF00668.20 ABK72267.1 - 0.016 13.9 0.1 0.11 11.2 0.1 1.8 1 1 1 2 2 2 0 Condensation domain Bac_luciferase PF00296.20 ABK72268.1 - 4.8e-39 134.6 4.0 6.6e-39 134.2 4.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Fic PF02661.18 ABK72269.1 - 2.7e-11 44.2 0.0 4.3e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Fic/DOC family Hexapep PF00132.24 ABK72270.1 - 1.8e-08 33.8 4.6 6.6e-05 22.5 1.3 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 ABK72270.1 - 0.0044 16.8 1.7 0.012 15.3 0.2 2.4 2 1 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Ribosomal_L4 PF00573.22 ABK72271.1 - 1.3e-65 220.7 0.2 1.6e-65 220.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Exo_endo_phos PF03372.23 ABK72272.1 - 1.4e-20 73.9 0.4 1.6e-20 73.6 0.4 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PQQ PF01011.21 ABK72273.1 - 9.3e-34 113.8 14.3 1.4e-06 28.0 0.0 7.7 7 0 0 7 7 7 7 PQQ enzyme repeat PQQ_2 PF13360.6 ABK72273.1 - 4e-26 92.1 6.3 3e-15 56.5 0.9 3.6 2 1 1 3 3 3 3 PQQ-like domain PQQ_3 PF13570.6 ABK72273.1 - 1.1e-19 70.3 34.9 5.2e-08 33.1 0.2 8.1 8 1 0 8 8 8 4 PQQ-like domain Ala_racemase_N PF01168.20 ABK72274.1 - 9.4e-18 64.7 0.1 1.2e-17 64.3 0.1 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain AAA_lid_2 PF17863.1 ABK72276.1 - 7.1e-19 67.4 5.7 7.1e-19 67.4 5.7 3.0 3 0 0 3 3 2 1 AAA lid domain VWA_2 PF13519.6 ABK72276.1 - 3e-15 56.8 0.1 7.1e-15 55.6 0.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA_5 PF07728.14 ABK72276.1 - 1e-13 51.4 0.0 1.9e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) VWA PF00092.28 ABK72276.1 - 5.2e-13 49.6 0.0 8.7e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Mg_chelatase PF01078.21 ABK72276.1 - 4.5e-11 42.5 0.2 2.7e-08 33.4 0.0 2.6 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI MCM PF00493.23 ABK72276.1 - 6.2e-07 28.7 0.0 1.6e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 MCM P-loop domain Sigma54_activat PF00158.26 ABK72276.1 - 3.4e-05 23.6 0.0 6.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain VWA_3 PF13768.6 ABK72276.1 - 0.00013 21.9 0.1 0.00025 21.0 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA PF00004.29 ABK72276.1 - 0.0031 17.9 0.0 0.032 14.7 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 ABK72276.1 - 0.005 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Trypan_PARP PF05887.11 ABK72276.1 - 0.0082 16.1 5.4 0.0082 16.1 5.4 2.0 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) AAA_16 PF13191.6 ABK72276.1 - 0.086 13.2 2.1 0.28 11.5 0.3 2.8 3 1 0 3 3 3 0 AAA ATPase domain Neisseria_TspB PF05616.13 ABK72276.1 - 7.7 4.9 6.9 12 4.3 6.9 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DUF2975 PF11188.8 ABK72277.1 - 0.041 13.8 2.0 0.051 13.5 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) PGPGW PF09656.10 ABK72279.1 - 1.8e-21 75.4 7.1 1.8e-21 75.4 7.1 2.0 2 0 0 2 2 2 1 Putative transmembrane protein (PGPGW) DUF4335 PF14233.6 ABK72279.1 - 0.068 13.1 0.1 0.36 10.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4335) RhodobacterPufX PF11511.8 ABK72279.1 - 4.9 6.8 11.1 0.062 12.9 1.9 2.2 2 1 0 2 2 2 0 Intrinsic membrane protein PufX DUF3040 PF11239.8 ABK72279.1 - 6.5 7.1 11.2 0.45 10.8 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) LytR_cpsA_psr PF03816.14 ABK72280.1 - 9.3e-41 139.5 0.0 1.6e-40 138.7 0.0 1.4 1 0 0 1 1 1 1 Cell envelope-related transcriptional attenuator domain LytR_C PF13399.6 ABK72280.1 - 1.7e-17 64.1 0.6 4e-17 63.0 0.6 1.7 1 0 0 1 1 1 1 LytR cell envelope-related transcriptional attenuator HMA PF00403.26 ABK72280.1 - 0.19 12.2 0.1 0.41 11.1 0.1 1.5 1 0 0 1 1 1 0 Heavy-metal-associated domain CMAS PF02353.20 ABK72281.1 - 8.7e-121 402.4 0.0 9.7e-121 402.2 0.0 1.0 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 ABK72281.1 - 4.3e-10 39.7 0.0 6.1e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABK72281.1 - 1.3e-08 35.5 0.0 2.7e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABK72281.1 - 4.6e-07 30.4 0.0 1e-06 29.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK72281.1 - 2.8e-06 28.0 0.0 4.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ABK72281.1 - 0.045 13.5 0.0 0.065 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 ABK72281.1 - 0.075 12.8 0.0 0.16 11.7 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 ABK72281.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.14 ABK72281.1 - 0.2 11.2 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain T7SS_ESX_EspC PF10824.8 ABK72283.1 - 3.2e-29 101.3 7.7 3.6e-29 101.2 7.7 1.0 1 0 0 1 1 1 1 Excreted virulence factor EspC, type VII ESX diderm PE PF00934.20 ABK72283.1 - 0.0037 17.5 9.9 0.0045 17.3 9.9 1.1 1 0 0 1 1 1 1 PE family Big_3_3 PF13750.6 ABK72283.1 - 0.019 14.6 0.1 0.024 14.3 0.1 1.0 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) Mannitol_dh PF01232.23 ABK72283.1 - 0.021 15.0 0.3 0.024 14.8 0.3 1.0 1 0 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain WXG100 PF06013.12 ABK72283.1 - 0.056 13.7 4.4 0.8 10.0 0.2 2.2 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Ribosomal_S18 PF01084.20 ABK72284.1 - 5.7e-23 80.9 0.4 7.1e-23 80.6 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S18 AAA_31 PF13614.6 ABK72285.1 - 6e-61 205.4 0.0 7.3e-61 205.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 ABK72285.1 - 1.3e-25 89.9 0.0 6.6e-25 87.6 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 ABK72285.1 - 2.3e-11 43.6 0.0 1.7e-10 40.8 0.0 1.9 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 ABK72285.1 - 1.6e-09 37.6 0.0 2.8e-08 33.5 0.0 2.0 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.11 ABK72285.1 - 1.2e-08 34.6 0.3 7.6e-05 22.1 0.1 2.2 2 0 0 2 2 2 2 ATPase MipZ ParA PF10609.9 ABK72285.1 - 1.2e-07 31.4 0.1 6.7e-07 29.0 0.1 2.0 3 0 0 3 3 3 1 NUBPL iron-transfer P-loop NTPase ArsA_ATPase PF02374.15 ABK72285.1 - 2.8e-07 30.0 0.1 5e-07 29.2 0.1 1.6 1 1 0 1 1 1 1 Anion-transporting ATPase VirC1 PF07015.11 ABK72285.1 - 7.2e-06 25.5 0.1 4.8e-05 22.8 0.1 2.0 2 0 0 2 2 2 1 VirC1 protein MeaB PF03308.16 ABK72285.1 - 0.0079 15.2 0.7 0.013 14.5 0.2 1.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF1611 PF07755.11 ABK72285.1 - 0.022 14.0 0.0 0.12 11.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_C) P-loop domain CLP1_P PF16575.5 ABK72285.1 - 0.036 13.9 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop SRP54 PF00448.22 ABK72285.1 - 0.18 11.4 0.1 0.54 9.9 0.1 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF349 PF03993.12 ABK72286.1 - 3.5e-49 165.0 56.1 1.1e-20 73.7 4.6 4.4 4 0 0 4 4 4 3 Domain of Unknown Function (DUF349) Abhydrolase_6 PF12697.7 ABK72287.1 - 4.1e-20 73.3 9.6 4.8e-20 73.1 9.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 ABK72287.1 - 1.4e-09 37.9 0.1 2.3e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK72287.1 - 0.00016 21.1 0.1 0.22 10.7 0.1 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ABK72287.1 - 0.0049 16.6 1.7 0.35 10.5 1.3 2.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.13 ABK72287.1 - 0.068 12.9 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 PGAP1-like protein ABC_tran PF00005.27 ABK72288.1 - 2.9e-32 112.1 0.0 4e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK72288.1 - 4.5e-08 33.3 0.0 0.005 16.7 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system TOBE_2 PF08402.10 ABK72288.1 - 2.9e-07 30.5 2.1 2.9e-07 30.5 2.1 3.4 3 2 1 4 4 4 1 TOBE domain SMC_N PF02463.19 ABK72288.1 - 0.0005 19.6 0.0 0.27 10.6 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ABK72288.1 - 0.0015 18.8 0.3 0.012 15.9 0.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ABK72288.1 - 0.0019 18.6 2.9 0.0094 16.3 2.9 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 ABK72288.1 - 0.0079 16.6 0.0 0.033 14.6 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 ABK72288.1 - 0.023 14.6 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Rad17 PF03215.15 ABK72288.1 - 0.032 14.2 0.0 0.049 13.5 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 ABK72288.1 - 0.037 13.8 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 ABK72288.1 - 0.067 13.7 0.0 0.099 13.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ABK72288.1 - 0.093 12.9 0.2 0.48 10.6 0.2 2.2 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 ABK72288.1 - 0.094 13.0 0.4 0.79 10.0 0.4 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 ABK72288.1 - 0.096 12.9 1.0 0.38 11.0 0.1 2.2 2 1 1 3 3 3 0 AAA domain KdpD PF02702.17 ABK72288.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain ATPase_2 PF01637.18 ABK72288.1 - 0.17 11.7 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 ABK72288.1 - 0.21 11.5 0.8 0.39 10.6 0.3 1.7 2 0 0 2 2 2 0 NACHT domain BPD_transp_1 PF00528.22 ABK72289.1 - 5e-24 85.1 22.3 5e-24 85.1 22.3 1.7 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DBI_PRT PF02277.17 ABK72290.1 - 1.4e-136 455.1 17.6 1.5e-136 454.9 17.6 1.0 1 0 0 1 1 1 1 Phosphoribosyltransferase AAA_5 PF07728.14 ABK72291.1 - 6e-12 45.7 0.0 1.1e-11 44.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 ABK72291.1 - 1.1e-10 42.1 0.0 2.2e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ABK72291.1 - 4.1e-06 27.3 0.4 9.7e-06 26.1 0.3 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_3 PF07726.11 ABK72291.1 - 2e-05 24.4 0.0 0.058 13.3 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 ABK72291.1 - 0.00025 21.2 0.0 0.00047 20.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 ABK72291.1 - 0.0005 20.4 0.1 0.0018 18.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 ABK72291.1 - 0.0012 18.7 0.0 0.84 9.4 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 ABK72291.1 - 0.0018 18.8 0.0 0.0039 17.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_6 PF12774.7 ABK72291.1 - 0.0037 16.3 0.0 0.0059 15.6 0.0 1.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region Sigma54_activat PF00158.26 ABK72291.1 - 0.0056 16.4 0.0 0.82 9.4 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.6 ABK72291.1 - 0.006 16.9 0.8 0.093 13.1 0.5 2.7 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 ABK72291.1 - 0.0068 16.1 0.2 0.017 14.9 0.2 1.7 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 ABK72291.1 - 0.0091 16.0 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 ABK72291.1 - 0.019 14.9 0.5 0.056 13.4 0.0 1.9 2 1 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 ABK72291.1 - 0.033 14.4 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 ABK72291.1 - 0.034 14.0 0.0 0.071 13.0 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea TIP49 PF06068.13 ABK72291.1 - 0.058 12.6 0.3 0.32 10.2 0.0 1.9 2 0 0 2 2 2 0 TIP49 P-loop domain IPT PF01745.16 ABK72291.1 - 0.078 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase CbiG_N PF11760.8 ABK72291.1 - 0.14 12.2 0.1 4 7.5 0.0 2.4 2 0 0 2 2 2 0 Cobalamin synthesis G N-terminal Proton_antipo_M PF00361.20 ABK72292.1 - 3.2e-71 239.9 19.7 5.9e-71 239.1 19.7 1.5 1 0 0 1 1 1 1 Proton-conducting membrane transporter DUF1127 PF06568.11 ABK72294.1 - 0.053 13.3 1.0 0.053 13.3 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1127) Big_10 PF17964.1 ABK72295.1 - 1.2e-66 224.2 0.5 1.7e-66 223.6 0.5 1.2 1 0 0 1 1 1 1 Bacterial Ig domain YkuD PF03734.14 ABK72295.1 - 5.7e-19 69.0 0.9 9.6e-19 68.2 0.9 1.4 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain Big_5 PF13205.6 ABK72295.1 - 2.3e-09 37.9 0.2 0.00013 22.6 0.0 2.7 2 0 0 2 2 2 2 Bacterial Ig-like domain Acyl_transf_3 PF01757.22 ABK72296.1 - 1.9e-20 73.2 23.3 2.9e-20 72.6 23.3 1.3 1 0 0 1 1 1 1 Acyltransferase family Bac_luciferase PF00296.20 ABK72297.1 - 1.4e-09 37.9 7.9 9.2e-05 22.0 2.2 2.2 1 1 1 2 2 2 2 Luciferase-like monooxygenase IspA PF04279.15 ABK72298.1 - 0.01 16.0 8.8 0.05 13.8 9.0 1.8 1 1 1 2 2 2 0 Intracellular septation protein A DUF2304 PF10066.9 ABK72298.1 - 1 9.6 8.6 0.33 11.2 0.3 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) Bacteriocin_IIc PF10439.9 ABK72298.1 - 2.8 8.1 5.7 0.68 10.1 0.9 2.4 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide DUF3792 PF12670.7 ABK72298.1 - 6.8 6.9 10.0 3.4 7.9 7.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) DUF732 PF05305.14 ABK72299.1 - 1.3e-26 92.8 1.0 1.6e-26 92.5 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF732) FMN_red PF03358.15 ABK72300.1 - 1.7e-33 115.5 0.2 2.7e-33 114.9 0.2 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 ABK72300.1 - 1.8e-07 31.0 0.0 2.8e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold adh_short_C2 PF13561.6 ABK72301.1 - 9.9e-62 208.5 0.2 1.7e-61 207.7 0.2 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK72301.1 - 7.5e-55 185.4 0.3 3.3e-54 183.3 0.3 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK72301.1 - 2.5e-14 53.6 0.5 4.8e-10 39.6 0.0 2.1 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 ABK72301.1 - 8.8e-08 31.9 0.1 1.7e-07 31.0 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 ABK72301.1 - 0.0017 18.2 0.0 0.0027 17.6 0.0 1.2 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein DUF1776 PF08643.10 ABK72301.1 - 0.0022 17.4 0.0 0.0029 17.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) 3Beta_HSD PF01073.19 ABK72301.1 - 0.0084 15.1 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ABK72301.1 - 0.018 14.1 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 ABK72301.1 - 0.019 14.4 0.2 0.25 10.7 0.2 2.1 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_8 PF13450.6 ABK72301.1 - 0.032 14.5 0.1 0.066 13.5 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_10 PF13460.6 ABK72301.1 - 0.096 12.6 0.3 0.18 11.7 0.3 1.5 1 1 0 1 1 1 0 NAD(P)H-binding Abhydrolase_1 PF00561.20 ABK72302.1 - 4.9e-15 55.9 0.2 9.9e-15 54.9 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK72302.1 - 5.4e-13 50.1 3.3 7.5e-13 49.6 3.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family FR47 PF08445.10 ABK72303.1 - 4.1e-08 33.1 0.0 7.6e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 ABK72303.1 - 1.3e-07 31.9 0.0 2.6e-07 30.9 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 ABK72303.1 - 2.6e-05 23.9 0.2 0.0021 17.7 0.1 2.2 1 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ABK72303.1 - 2.8e-05 24.5 0.0 4.8e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ABK72303.1 - 2.9e-05 24.0 0.0 4.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ABK72303.1 - 0.00055 20.0 0.1 0.001 19.1 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ABK72303.1 - 0.00057 20.6 0.0 0.0011 19.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 ABK72303.1 - 0.0096 15.5 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_CG PF14542.6 ABK72303.1 - 0.05 13.7 0.0 0.095 12.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PRiA4_ORF3 PF07929.11 ABK72304.1 - 1.4e-51 174.6 0.0 1.7e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein Beta-lactamase PF00144.24 ABK72305.1 - 5.7e-60 203.3 0.1 7.3e-60 202.9 0.1 1.0 1 0 0 1 1 1 1 Beta-lactamase PP2C_2 PF13672.6 ABK72306.1 - 4.5e-13 49.3 0.8 7.3e-13 48.6 0.8 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 ABK72306.1 - 3e-07 30.4 0.0 3e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.12 ABK72306.1 - 0.0045 16.9 5.5 0.028 14.3 5.5 2.1 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) ADH_N PF08240.12 ABK72307.1 - 9.8e-21 73.7 0.2 2e-20 72.7 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ABK72307.1 - 3.4e-20 72.3 0.1 5.9e-20 71.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ABK72307.1 - 4.4e-15 55.7 0.0 7e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 ABK72307.1 - 0.021 15.9 0.2 0.19 12.8 0.0 2.4 1 1 1 2 2 2 0 Zinc-binding dehydrogenase CoA_trans PF01144.23 ABK72308.1 - 8e-34 116.9 0.4 5.1e-31 107.8 0.0 2.8 2 1 0 2 2 2 2 Coenzyme A transferase Mal_decarbox_Al PF16957.5 ABK72308.1 - 1.1e-05 24.0 0.7 1.8e-05 23.3 0.1 1.5 2 0 0 2 2 2 1 Malonate decarboxylase, alpha subunit, transporter AcetylCoA_hydro PF02550.15 ABK72308.1 - 0.054 13.5 0.0 2.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Acetyl-CoA hydrolase/transferase N-terminal domain MMPL PF03176.15 ABK72310.1 - 5.4e-93 311.5 15.3 5.4e-93 311.5 15.3 1.4 2 0 0 2 2 2 1 MMPL family Sterol-sensing PF12349.8 ABK72310.1 - 0.0029 17.5 0.2 0.012 15.4 0.9 1.7 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 ABK72310.1 - 0.074 10.7 8.9 0.1 10.3 8.9 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family ECH_1 PF00378.20 ABK72311.1 - 1e-56 192.0 0.2 1.3e-56 191.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK72311.1 - 7e-32 111.2 0.6 6e-31 108.2 0.6 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase TetR_N PF00440.23 ABK72312.1 - 1.7e-08 34.1 0.3 3.9e-08 32.9 0.1 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_IclR PF09339.10 ABK72312.1 - 3.3e-06 26.8 1.1 0.00038 20.2 0.1 2.5 2 0 0 2 2 2 2 IclR helix-turn-helix domain HTH_7 PF02796.15 ABK72312.1 - 0.013 15.5 0.0 0.18 11.9 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase LacI PF00356.21 ABK72312.1 - 0.015 15.1 0.1 0.041 13.7 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family MarR_2 PF12802.7 ABK72312.1 - 0.081 12.8 0.8 0.6 10.0 0.1 2.5 3 0 0 3 3 3 0 MarR family HTH_Tnp_1_2 PF13022.6 ABK72312.1 - 0.23 11.6 0.0 0.35 11.0 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase Acyl-CoA_dh_1 PF00441.24 ABK72313.1 - 5.8e-31 107.7 8.0 2.7e-15 56.9 1.7 2.8 3 0 0 3 3 3 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK72313.1 - 9.5e-20 71.4 0.2 2.3e-09 37.9 0.0 2.8 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ABK72313.1 - 2.1e-19 69.5 0.0 9.8e-19 67.4 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain DUF5058 PF16481.5 ABK72313.1 - 0.064 12.9 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5058) DUF1697 PF08002.11 ABK72314.1 - 1.1e-38 132.8 0.0 1.5e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1697) EHN PF06441.12 ABK72315.1 - 2.3e-39 134.1 0.1 5.7e-39 132.8 0.0 1.7 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 ABK72315.1 - 1.4e-13 51.1 0.4 3.2e-13 49.9 0.4 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK72315.1 - 4.8e-06 27.3 1.8 4.8e-06 27.3 1.8 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK72315.1 - 0.098 11.9 0.0 0.51 9.6 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Glycos_transf_3 PF00591.21 ABK72316.1 - 5.4e-29 101.5 1.7 7.2e-29 101.1 1.7 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain PYNP_C PF07831.13 ABK72316.1 - 5.4e-20 70.8 0.0 1.1e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 Pyrimidine nucleoside phosphorylase C-terminal domain Glycos_trans_3N PF02885.17 ABK72316.1 - 4.2e-15 55.3 0.0 4.2e-15 55.3 0.0 2.7 4 0 0 4 4 4 1 Glycosyl transferase family, helical bundle domain AP_endonuc_2 PF01261.24 ABK72317.1 - 3.2e-23 82.3 0.7 4.2e-23 81.9 0.7 1.3 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Pup_ligase PF03136.15 ABK72318.1 - 1.8e-160 534.8 0.1 3.6e-160 533.8 0.1 1.4 1 1 0 1 1 1 1 Pup-ligase protein Sigma70_r2 PF04542.14 ABK72319.1 - 7.6e-15 54.4 0.3 1.9e-14 53.1 0.2 1.7 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 ABK72319.1 - 1.2e-13 50.4 0.1 3.4e-13 49.0 0.0 1.8 1 1 1 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 ABK72319.1 - 1.4e-07 30.9 0.0 3.8e-07 29.5 0.0 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 ABK72319.1 - 0.00081 19.3 0.0 0.0017 18.3 0.0 1.5 1 1 0 1 1 1 1 ECF sigma factor p450 PF00067.22 ABK72320.1 - 3.1e-30 105.3 0.0 1.4e-26 93.3 0.0 3.0 1 1 0 1 1 1 1 Cytochrome P450 TetR_N PF00440.23 ABK72321.1 - 1.7e-12 46.9 0.1 3e-12 46.1 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family LysR_substrate PF03466.20 ABK72321.1 - 0.0002 20.8 0.4 0.15 11.4 0.0 2.2 2 0 0 2 2 2 2 LysR substrate binding domain HTH_IclR PF09339.10 ABK72321.1 - 0.0015 18.3 0.0 0.0033 17.2 0.0 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain TetR_C_15 PF17918.1 ABK72321.1 - 0.0028 18.4 0.7 0.0028 18.4 0.7 2.0 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_24 PF17932.1 ABK72321.1 - 0.0036 17.5 0.2 0.0075 16.5 0.2 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain NAD_binding_11 PF14833.6 ABK72322.1 - 9.4e-31 106.6 0.2 1.5e-30 105.9 0.2 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 ABK72322.1 - 3e-29 102.2 0.1 4.6e-29 101.6 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ABK72322.1 - 0.015 15.9 0.0 0.092 13.3 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh PF00984.19 ABK72322.1 - 0.07 13.3 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_7 PF13241.6 ABK72322.1 - 0.11 13.0 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding PG_binding_1 PF01471.18 ABK72323.1 - 6.7e-31 106.3 1.1 1.7e-15 56.9 0.1 3.2 3 1 0 3 3 3 2 Putative peptidoglycan binding domain Amidase_3 PF01520.18 ABK72323.1 - 3.9e-29 102.0 0.0 5.7e-29 101.5 0.0 1.3 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase PG_binding_3 PF09374.10 ABK72323.1 - 5.3e-08 33.0 0.0 0.075 13.3 0.0 3.4 2 1 1 3 3 3 3 Predicted Peptidoglycan domain PG_binding_2 PF08823.11 ABK72323.1 - 8.4e-06 26.0 0.3 0.001 19.3 0.1 3.0 2 1 0 2 2 2 1 Putative peptidoglycan binding domain Nitroreductase PF00881.24 ABK72324.1 - 1.8e-12 47.7 0.0 2.8e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Nitroreductase family AAA_21 PF13304.6 ABK72325.1 - 2.3e-29 103.2 0.1 1.1e-20 74.7 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 ABK72325.1 - 3e-18 66.7 0.0 6e-09 36.1 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 ABK72325.1 - 8.4e-11 41.7 0.0 2.5e-05 23.8 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF2813 PF11398.8 ABK72325.1 - 2.7e-06 26.9 0.4 0.00096 18.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2813) AAA_23 PF13476.6 ABK72325.1 - 1.5e-05 25.6 0.0 2.2e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 ABK72325.1 - 0.00082 19.9 0.1 0.0077 16.8 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_18 PF13238.6 ABK72325.1 - 0.0047 17.5 0.0 0.0091 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ABK72325.1 - 0.01 15.5 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 ABK72325.1 - 0.017 14.7 1.2 0.04 13.5 0.0 2.1 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 ABK72325.1 - 0.024 14.4 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ABK72325.1 - 0.031 14.7 3.6 0.18 12.2 0.1 2.6 2 1 1 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 ABK72325.1 - 0.072 13.4 0.1 0.2 11.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 ABK72325.1 - 0.077 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ABK72325.1 - 0.098 12.9 0.2 0.22 11.8 0.2 1.6 1 0 0 1 1 1 0 AAA domain Mur_ligase_M PF08245.12 ABK72327.1 - 3.9e-20 72.7 0.0 5.7e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 ABK72327.1 - 1.8e-11 44.1 0.2 8.6e-11 42.0 0.2 2.2 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Esterase PF00756.20 ABK72328.1 - 1e-15 58.1 0.2 1.5e-15 57.5 0.2 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 ABK72328.1 - 0.008 15.7 0.2 0.013 14.9 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 ABK72328.1 - 0.0085 15.8 0.1 0.02 14.6 0.1 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 ABK72328.1 - 0.079 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Hydrolase_4 PF12146.8 ABK72328.1 - 0.091 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 CobN-Mg_chel PF02514.16 ABK72329.1 - 0 1347.5 0.0 0 1347.3 0.0 1.0 1 0 0 1 1 1 1 CobN/Magnesium Chelatase Nuc_deoxyri_tr3 PF11071.8 ABK72329.1 - 0.19 11.8 0.0 0.94 9.5 0.0 2.2 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase YtoQ zf-SAP30 PF13866.6 ABK72329.1 - 0.2 11.8 0.1 0.64 10.2 0.0 1.9 2 0 0 2 2 2 0 SAP30 zinc-finger BPD_transp_1 PF00528.22 ABK72330.1 - 6.2e-11 42.4 14.3 6.2e-11 42.4 14.3 1.8 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Peripla_BP_4 PF13407.6 ABK72331.1 - 2.9e-58 197.5 11.8 3.7e-58 197.1 11.8 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain ZnuA PF01297.17 ABK72331.1 - 0.016 14.7 0.1 1.8 7.9 0.0 2.2 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic TetR_N PF00440.23 ABK72332.1 - 4.1e-13 48.9 2.2 7.9e-13 48.0 0.4 2.4 3 0 0 3 3 3 1 Bacterial regulatory proteins, tetR family HTH_Tnp_1_2 PF13022.6 ABK72332.1 - 0.014 15.5 0.1 0.024 14.8 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase TetR_C_14 PF17754.1 ABK72332.1 - 0.076 13.0 0.4 0.076 13.0 0.4 2.6 2 2 0 2 2 2 0 MftR C-terminal domain HTH_23 PF13384.6 ABK72332.1 - 0.089 12.6 0.2 0.29 11.0 0.2 1.9 1 0 0 1 1 1 0 Homeodomain-like domain HTH_31 PF13560.6 ABK72332.1 - 0.14 12.5 0.6 0.99 9.8 0.3 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain TetR_N PF00440.23 ABK72333.1 - 5.2e-12 45.4 0.1 1.5e-11 43.9 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_Tnp_1_2 PF13022.6 ABK72333.1 - 7.9e-05 22.8 0.0 0.0002 21.5 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix of insertion element transposase HTH_23 PF13384.6 ABK72333.1 - 0.00076 19.2 1.2 0.0011 18.6 0.1 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_IclR PF09339.10 ABK72333.1 - 0.00088 19.0 0.3 0.0077 16.0 0.0 2.6 3 0 0 3 3 3 1 IclR helix-turn-helix domain HTH_3 PF01381.22 ABK72333.1 - 0.0011 19.0 0.0 0.0031 17.5 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 ABK72333.1 - 0.0015 18.8 0.7 0.3 11.4 0.1 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.15 ABK72333.1 - 0.005 16.9 0.0 0.023 14.8 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_Tnp_1 PF01527.20 ABK72333.1 - 0.0095 16.2 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 1 Transposase HTH_17 PF12728.7 ABK72333.1 - 0.011 15.9 0.0 0.025 14.7 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 ABK72333.1 - 0.011 15.1 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 CENP-B_N PF04218.13 ABK72333.1 - 0.018 14.6 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_AraC PF00165.23 ABK72333.1 - 0.03 14.4 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family Phage_AlpA PF05930.12 ABK72333.1 - 0.037 13.9 0.0 0.081 12.8 0.0 1.6 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) HTH_29 PF13551.6 ABK72333.1 - 0.038 14.0 0.0 0.099 12.7 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix HTH_28 PF13518.6 ABK72333.1 - 0.049 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_26 PF13443.6 ABK72333.1 - 0.17 12.3 0.0 1.3 9.5 0.0 2.1 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain DUF5319 PF17252.2 ABK72334.1 - 5.9e-50 168.6 1.8 7e-50 168.3 1.8 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5319) Mce4_CUP1 PF11887.8 ABK72335.1 - 3.5e-93 311.8 0.0 4.4e-93 311.4 0.0 1.1 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative MlaD PF02470.20 ABK72335.1 - 5.1e-13 49.1 0.2 2.1e-12 47.1 0.1 1.9 2 0 0 2 2 2 1 MlaD protein MFS_1 PF07690.16 ABK72336.1 - 0.0032 16.5 0.2 0.0042 16.1 0.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_3_6 PF07332.11 ABK72336.1 - 0.013 15.5 1.0 0.015 15.3 1.0 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III INSIG PF07281.12 ABK72336.1 - 0.056 13.1 0.3 0.06 13.0 0.3 1.1 1 0 0 1 1 1 0 Insulin-induced protein (INSIG) Phage_holin_3_3 PF16083.5 ABK72336.1 - 0.1 12.7 3.7 1.4 9.1 0.2 2.1 1 1 0 2 2 2 0 LydA holin phage, holin superfamily III DUF5337 PF17272.2 ABK72336.1 - 0.13 12.1 2.9 0.18 11.6 2.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5337) DUF4956 PF16316.5 ABK72337.1 - 7.5e-27 94.1 10.9 7.5e-27 94.1 10.9 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4956) MgtC PF02308.16 ABK72337.1 - 9.8e-07 29.2 13.3 1.5e-06 28.6 13.3 1.3 1 0 0 1 1 1 1 MgtC family DUF5367 PF17329.2 ABK72337.1 - 0.15 12.2 9.7 0.34 11.1 1.9 3.1 3 1 0 3 3 3 0 Family of unknown function (DUF5367) DUF3488 PF11992.8 ABK72337.1 - 0.18 10.8 9.7 0.24 10.3 9.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) DUF2104 PF09877.9 ABK72337.1 - 1.4 9.3 13.5 26 5.1 13.5 2.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2104) Cytochrom_B_C PF00032.17 ABK72337.1 - 4 7.8 9.5 0.66 10.3 3.9 2.2 1 1 1 2 2 2 0 Cytochrome b(C-terminal)/b6/petD SUR7 PF06687.12 ABK72337.1 - 4.5 6.8 10.1 8 6.0 10.1 1.4 1 0 0 1 1 1 0 SUR7/PalI family PHO4 PF01384.20 ABK72337.1 - 7.9 5.4 12.3 5.1 6.0 4.1 2.0 1 1 1 2 2 2 0 Phosphate transporter family DUF3043 PF11241.8 ABK72337.1 - 9.5 6.2 9.5 21 5.1 3.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) MarR PF01047.22 ABK72338.1 - 3.5e-16 58.9 0.0 6.3e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 ABK72338.1 - 1.2e-10 41.1 0.4 1.2e-10 41.1 0.4 1.9 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 ABK72338.1 - 2.5e-09 37.5 0.3 9.2e-09 35.7 0.1 2.0 2 0 0 2 2 2 1 Winged helix DNA-binding domain HxlR PF01638.17 ABK72338.1 - 5.4e-06 26.2 0.0 4.1e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 HxlR-like helix-turn-helix HTH_20 PF12840.7 ABK72338.1 - 0.00064 19.7 0.7 0.0015 18.5 0.7 1.8 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 ABK72338.1 - 0.0031 17.3 0.1 0.0048 16.7 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_34 PF13601.6 ABK72338.1 - 0.0079 16.3 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_24 PF13412.6 ABK72338.1 - 0.014 14.9 0.0 0.051 13.2 0.0 2.0 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF294_C PF10335.9 ABK72338.1 - 0.023 14.5 0.9 0.042 13.6 0.9 1.5 1 0 0 1 1 1 0 Putative nucleotidyltransferase substrate binding domain DUF4089 PF13318.6 ABK72338.1 - 0.051 14.0 1.8 0.22 12.0 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4089) DUF2732 PF10809.8 ABK72338.1 - 0.065 13.1 3.8 0.41 10.5 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2732) DUF2513 PF10711.9 ABK72338.1 - 0.071 13.4 0.0 0.33 11.3 0.0 1.9 2 0 0 2 2 2 0 Hypothetical protein (DUF2513) PadR PF03551.14 ABK72338.1 - 0.076 13.0 0.0 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family Fe_dep_repress PF01325.19 ABK72338.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain DUF417 PF04224.12 ABK72339.1 - 2.2e-10 40.4 0.0 2.3e-10 40.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF417 Bac_luciferase PF00296.20 ABK72340.1 - 2.4e-40 138.9 0.4 3.6e-40 138.3 0.4 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Molybdopterin PF00384.22 ABK72341.1 - 6e-39 134.2 0.0 7.1e-39 134.0 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 ABK72341.1 - 2.5e-20 72.6 0.1 5.6e-20 71.4 0.1 1.6 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 ABK72341.1 - 8.7e-10 38.5 0.0 1.8e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain GerE PF00196.19 ABK72342.1 - 5.2e-18 64.3 0.8 8.3e-18 63.7 0.8 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Response_reg PF00072.24 ABK72342.1 - 1.9e-07 31.2 0.0 3.2e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HTH_23 PF13384.6 ABK72342.1 - 2.7e-05 23.8 1.1 0.00017 21.3 0.2 2.4 1 1 1 2 2 2 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 ABK72342.1 - 7.6e-05 22.3 0.2 0.00023 20.8 0.2 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 ABK72342.1 - 0.003 17.3 0.2 0.0074 16.0 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 ABK72342.1 - 0.0089 15.5 0.5 0.017 14.6 0.5 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 TadZ_N PF16968.5 ABK72342.1 - 0.019 14.7 1.2 0.034 13.9 1.2 1.4 1 0 0 1 1 1 0 Pilus assembly protein TadZ N-terminal HTH_40 PF14493.6 ABK72342.1 - 0.021 15.3 0.2 0.043 14.3 0.2 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_27 PF13463.6 ABK72342.1 - 0.053 14.0 0.8 0.17 12.4 0.3 2.1 2 0 0 2 2 2 0 Winged helix DNA-binding domain HTH_29 PF13551.6 ABK72342.1 - 0.069 13.2 0.8 0.53 10.3 0.1 2.4 1 1 1 2 2 2 0 Winged helix-turn helix HTH_7 PF02796.15 ABK72342.1 - 0.073 13.2 1.1 0.14 12.3 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase Abhydrolase_6 PF12697.7 ABK72343.1 - 1.9e-07 31.9 1.7 2.3e-07 31.7 1.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 ABK72343.1 - 0.00018 21.3 0.1 0.00023 21.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ABK72343.1 - 0.00094 18.9 0.1 0.0022 17.7 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ABK72343.1 - 0.01 15.1 0.1 0.014 14.7 0.1 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 TetR_C_1 PF02909.17 ABK72344.1 - 1.3e-11 44.5 0.1 1.9e-11 44.0 0.1 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK72344.1 - 8.4e-06 25.5 0.4 1.7e-05 24.5 0.1 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_Tnp_ISL3 PF13542.6 ABK72344.1 - 0.049 13.1 0.1 1 8.9 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Ribosomal_S6 PF01250.17 ABK72345.1 - 3.4e-25 88.1 0.0 3.7e-25 88.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S6 Pcc1 PF09341.10 ABK72345.1 - 0.084 13.0 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Transcription factor Pcc1 AMP-binding PF00501.28 ABK72346.1 - 5.5e-69 232.8 0.0 6.6e-69 232.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK72346.1 - 3.3e-17 63.2 0.1 1.1e-16 61.5 0.1 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 ABK72346.1 - 0.076 11.9 0.0 1.2 7.9 0.0 2.0 2 0 0 2 2 2 0 GH3 auxin-responsive promoter AA_permease_2 PF13520.6 ABK72347.1 - 4.1e-30 105.0 44.4 5.6e-30 104.5 44.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ABK72347.1 - 4.5e-18 65.1 38.6 5.8e-18 64.8 38.6 1.1 1 0 0 1 1 1 1 Amino acid permease HypA PF01155.19 ABK72348.1 - 1.9e-29 102.0 0.3 2.1e-29 101.8 0.3 1.0 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA NMT1 PF09084.11 ABK72349.1 - 2.4e-08 34.2 0.0 5.2e-08 33.1 0.0 1.7 2 0 0 2 2 2 1 NMT1/THI5 like Phosphonate-bd PF12974.7 ABK72349.1 - 0.00083 19.0 0.1 0.0034 17.0 0.1 2.1 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_3 PF16868.5 ABK72349.1 - 0.0026 17.3 0.0 0.0038 16.7 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family Cons_hypoth95 PF03602.15 ABK72349.1 - 0.009 15.7 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 CoA_transf_3 PF02515.17 ABK72350.1 - 5.7e-85 285.6 0.1 7e-85 285.4 0.1 1.0 1 0 0 1 1 1 1 CoA-transferase family III Glyco_hydro_16 PF00722.21 ABK72351.1 - 8.7e-15 54.6 1.7 1.2e-14 54.2 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 HTH_Tnp_1 PF01527.20 ABK72352.1 - 4.6e-09 36.5 0.1 6.2e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 ABK72352.1 - 6.8e-06 25.7 0.6 1.7e-05 24.5 0.0 1.8 2 1 0 2 2 2 1 Homeodomain-like domain HTH_10 PF04967.12 ABK72352.1 - 0.0022 17.8 0.0 0.0088 15.8 0.0 2.0 2 1 1 3 3 3 1 HTH DNA binding domain HTH_28 PF13518.6 ABK72352.1 - 0.0031 17.6 0.0 0.0053 16.9 0.0 1.5 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_1_2 PF13022.6 ABK72352.1 - 0.0092 16.1 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix of insertion element transposase Sigma70_r4_2 PF08281.12 ABK72352.1 - 0.011 15.4 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_29 PF13551.6 ABK72352.1 - 0.016 15.2 0.0 0.028 14.5 0.0 1.4 1 1 0 1 1 1 0 Winged helix-turn helix ANT PF03374.14 ABK72352.1 - 0.04 14.2 0.0 0.062 13.6 0.0 1.3 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain Rrf2 PF02082.20 ABK72352.1 - 0.049 14.0 0.0 0.37 11.2 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator Terminase_5 PF06056.12 ABK72352.1 - 0.066 13.1 0.3 0.12 12.3 0.0 1.6 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) HTH_11 PF08279.12 ABK72352.1 - 0.072 13.0 0.1 0.36 10.8 0.0 2.0 2 0 0 2 2 2 0 HTH domain HTH_Tnp_ISL3 PF13542.6 ABK72352.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_AraC PF00165.23 ABK72352.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_7 PF02796.15 ABK72352.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase DUF977 PF06163.11 ABK72352.1 - 0.13 12.2 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) HTH_Tnp_4 PF13613.6 ABK72352.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease ADH_zinc_N_2 PF13602.6 ABK72353.1 - 4.2e-22 79.6 0.1 9e-22 78.6 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ABK72353.1 - 4e-17 62.4 0.9 8.8e-17 61.3 0.9 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ABK72353.1 - 9.1e-12 44.8 0.1 2.6e-09 36.9 0.0 2.6 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 ABK72353.1 - 0.039 13.4 0.4 0.074 12.5 0.4 1.5 1 0 0 1 1 1 0 short chain dehydrogenase MazE_antitoxin PF04014.18 ABK72353.1 - 0.16 12.0 0.0 10 6.2 0.0 2.7 2 0 0 2 2 2 0 Antidote-toxin recognition MazE, bacterial antitoxin Hexapep PF00132.24 ABK72354.1 - 1.4e-15 56.3 6.9 7.3e-08 31.8 1.4 4.2 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 ABK72354.1 - 7.9e-07 28.7 7.5 0.00066 19.4 2.1 3.6 4 0 0 4 4 4 3 Hexapeptide repeat of succinyl-transferase Abhydrolase_3 PF07859.13 ABK72355.1 - 3.8e-68 229.5 6.0 4.7e-68 229.2 6.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ABK72355.1 - 3.6e-13 49.2 1.4 1.1e-12 47.6 1.4 1.6 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase2 PF12740.7 ABK72355.1 - 7.2e-05 21.8 0.0 0.00013 21.0 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Esterase_phd PF10503.9 ABK72355.1 - 0.00081 18.9 3.9 0.13 11.8 3.9 2.5 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 ABK72355.1 - 0.002 17.6 0.1 0.0035 16.9 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 ABK72355.1 - 0.0069 16.1 0.9 0.057 13.0 0.9 2.0 1 1 0 1 1 1 1 Putative esterase AXE1 PF05448.12 ABK72355.1 - 0.018 13.8 0.6 0.11 11.2 0.3 1.9 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Chlorophyllase PF07224.11 ABK72355.1 - 0.03 13.4 0.0 0.047 12.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Say1_Mug180 PF10340.9 ABK72355.1 - 0.22 10.4 0.0 0.41 9.4 0.0 1.4 1 1 0 1 1 1 0 Steryl acetyl hydrolase MFS_1 PF07690.16 ABK72356.1 - 2.1e-36 125.6 49.9 2.1e-36 125.6 49.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK72356.1 - 8.3e-10 38.1 8.7 8.3e-10 38.1 8.7 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 ABK72356.1 - 4.7e-07 28.6 4.8 4.7e-07 28.6 4.8 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 ABK72356.1 - 0.32 10.3 48.3 0.44 9.8 48.3 1.1 1 0 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB Aminotran_1_2 PF00155.21 ABK72358.1 - 1.3e-17 64.1 0.0 1.6e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 ABK72358.1 - 4.9e-14 51.7 0.5 1.6e-13 50.0 0.5 2.0 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_41 PF14502.6 ABK72358.1 - 0.00017 21.2 0.0 0.00039 20.1 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 ABK72358.1 - 0.0029 17.6 0.1 0.01 15.8 0.0 1.8 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_20 PF12840.7 ABK72358.1 - 0.0059 16.6 0.2 1.4 9.1 0.1 2.9 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 ABK72358.1 - 0.012 15.5 5.6 0.023 14.6 0.5 3.6 4 0 0 4 4 4 0 MarR family HTH_24 PF13412.6 ABK72358.1 - 0.018 14.6 0.2 0.28 10.8 0.0 2.6 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 ABK72358.1 - 0.36 10.7 2.4 0.38 10.6 0.2 2.2 3 0 0 3 3 3 0 IclR helix-turn-helix domain Sigma70_r2 PF04542.14 ABK72359.1 - 1.4e-12 47.1 0.2 2.9e-12 46.2 0.2 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 ABK72359.1 - 1.3e-11 44.0 1.0 1.3e-11 44.0 1.0 2.0 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 ABK72359.1 - 7.1e-11 41.4 0.6 1.3e-10 40.6 0.6 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_16 PF12645.7 ABK72359.1 - 3.2e-06 27.1 0.0 4.9e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_ECF PF07638.11 ABK72359.1 - 0.00021 21.2 0.3 0.00037 20.4 0.3 1.3 1 1 0 1 1 1 1 ECF sigma factor GerE PF00196.19 ABK72359.1 - 0.14 11.8 0.2 0.32 10.6 0.1 1.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family BPD_transp_2 PF02653.16 ABK72360.1 - 1.2e-50 172.1 39.7 1.2e-50 172.1 39.7 1.6 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component DUF1427 PF07235.11 ABK72360.1 - 0.38 10.7 5.2 0.18 11.8 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1427) DUF2070 PF09843.9 ABK72360.1 - 5.8 5.1 10.8 8.2 4.6 10.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Ribosomal_S17 PF00366.20 ABK72361.1 - 6.2e-30 103.1 0.2 7.8e-30 102.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 ADH_zinc_N PF00107.26 ABK72362.1 - 4e-20 72.1 0.9 1.1e-19 70.7 0.9 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ABK72362.1 - 6.9e-19 67.7 0.4 1.4e-18 66.7 0.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 ABK72362.1 - 0.00032 20.3 2.1 0.00065 19.2 2.1 1.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 ABK72362.1 - 0.057 14.5 0.2 0.17 12.9 0.2 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ABK72363.1 - 3.4e-27 95.0 0.7 5.6e-27 94.3 0.7 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ABK72363.1 - 2.9e-18 67.2 0.0 7.1e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ABK72363.1 - 1.1e-11 44.6 0.9 7.7e-10 38.6 0.0 2.7 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 ABK72363.1 - 0.00074 18.9 0.4 0.0014 17.9 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 ABK72363.1 - 0.011 15.2 0.2 0.019 14.4 0.2 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Glu_dehyd_C PF16912.5 ABK72363.1 - 0.043 13.3 0.4 0.071 12.6 0.4 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Thiolase_N PF00108.23 ABK72364.1 - 5.5e-13 48.9 0.0 1.7e-12 47.2 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ABK72364.1 - 1.1e-09 38.0 0.1 2.4e-08 33.7 0.2 2.4 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ABK72364.1 - 0.0012 18.5 1.5 0.0023 17.5 0.3 2.2 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 ABK72364.1 - 0.0039 15.9 0.0 0.0065 15.2 0.0 1.2 1 0 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) NUMOD4 PF07463.11 ABK72364.1 - 0.069 13.4 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 NUMOD4 motif YCII PF03795.14 ABK72365.1 - 1.2e-15 57.6 0.0 1.9e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 YCII-related domain Rubredoxin PF00301.20 ABK72366.1 - 2.2e-21 75.6 8.4 2.4e-21 75.5 8.4 1.1 1 0 0 1 1 1 1 Rubredoxin Zn_Tnp_IS1595 PF12760.7 ABK72366.1 - 0.018 15.0 0.6 0.52 10.3 0.1 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 ABK72366.1 - 0.043 13.7 1.3 0.18 11.8 1.3 1.8 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zf-H2C2_2 PF13465.6 ABK72366.1 - 0.22 12.0 5.3 2.2 8.9 0.4 2.2 2 0 0 2 2 2 0 Zinc-finger double domain Zn_ribbon_SprT PF17283.2 ABK72366.1 - 0.35 10.8 6.9 2.8 7.9 0.5 2.1 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Zn-C2H2_12 PF18112.1 ABK72366.1 - 0.41 11.2 3.0 0.63 10.5 0.1 2.4 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-ribbon_3 PF13248.6 ABK72366.1 - 0.58 9.7 7.3 3.6 7.1 2.7 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 ABK72366.1 - 0.91 9.7 6.5 9 6.5 6.5 2.1 1 1 0 1 1 1 0 Zinc ribbon domain PHD_4 PF16866.5 ABK72366.1 - 1 9.5 8.1 3.9 7.6 8.1 1.8 1 1 0 1 1 1 0 PHD-finger zf-C2H2 PF00096.26 ABK72366.1 - 8.2 7.1 7.5 4.7 7.9 0.3 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type SBP_bac_3 PF00497.20 ABK72368.1 - 2.2e-33 115.6 0.0 2.5e-33 115.4 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 SBP_bac_11 PF13531.6 ABK72368.1 - 0.00016 21.5 0.1 0.00032 20.5 0.0 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein UPRTase PF14681.6 ABK72369.1 - 2.6e-60 203.4 0.0 2.9e-60 203.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 ABK72369.1 - 9.2e-08 31.8 0.2 1.4e-07 31.2 0.2 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF732 PF05305.14 ABK72370.1 - 3.2e-05 24.2 5.4 6.9e-05 23.2 5.4 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF732) HATPase_c PF02518.26 ABK72371.1 - 4.2e-25 88.4 0.0 6.4e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ABK72371.1 - 1.3e-19 70.0 0.5 3.5e-19 68.6 0.5 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 ABK72371.1 - 3.1e-08 33.9 0.7 1.2e-07 32.0 0.7 2.1 1 0 0 1 1 1 1 HAMP domain HATPase_c_2 PF13581.6 ABK72371.1 - 5.2e-05 23.2 0.0 0.00013 21.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 ABK72371.1 - 0.0031 17.4 0.0 0.0049 16.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Transcrip_act PF04949.13 ABK72371.1 - 0.012 15.5 0.1 0.018 14.9 0.1 1.2 1 0 0 1 1 1 0 Transcriptional activator HTH_25 PF13413.6 ABK72372.1 - 0.00016 21.5 1.8 0.00029 20.6 0.5 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_31 PF13560.6 ABK72372.1 - 0.0097 16.2 0.4 0.0097 16.2 0.4 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain DUF1869 PF08956.10 ABK72372.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1869) AraC_binding_2 PF14525.6 ABK72373.1 - 1.6e-34 119.1 6.5 3.1e-34 118.1 6.5 1.4 1 0 0 1 1 1 1 AraC-binding-like domain HTH_18 PF12833.7 ABK72373.1 - 2.4e-26 91.8 0.2 6.4e-26 90.4 0.2 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 ABK72373.1 - 4.1e-13 49.1 0.0 4.5e-06 26.6 0.0 2.5 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_23 PF13384.6 ABK72373.1 - 0.15 11.9 0.6 17 5.3 0.0 3.7 3 1 1 4 4 4 0 Homeodomain-like domain CRCB PF02537.15 ABK72374.1 - 1.3e-24 86.3 9.3 1.6e-24 86.0 9.3 1.0 1 0 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) CbiM PF01891.16 ABK72374.1 - 0.0061 16.4 5.6 0.0086 15.9 5.6 1.2 1 0 0 1 1 1 1 Cobalt uptake substrate-specific transmembrane region DUF3180 PF11377.8 ABK72374.1 - 1.2 9.2 15.6 0.21 11.7 2.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3180) Arabinose_trans PF04602.12 ABK72375.1 - 2e-204 679.7 37.7 3.3e-204 678.9 37.7 1.3 1 0 0 1 1 1 1 Mycobacterial cell wall arabinan synthesis protein Arabino_trans_C PF14896.6 ABK72375.1 - 2.1e-156 520.8 1.0 2.6e-156 520.5 1.0 1.1 1 0 0 1 1 1 1 EmbC C-terminal domain Arabino_trans_N PF17689.1 ABK72375.1 - 9.5e-50 168.8 0.1 1.8e-49 167.9 0.1 1.5 1 0 0 1 1 1 1 Arabinosyltransferase concanavalin like domain Phos_pyr_kin PF08543.12 ABK72376.1 - 9.7e-86 287.1 0.1 1.1e-85 287.0 0.1 1.0 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 ABK72376.1 - 3.3e-11 43.0 0.0 6.1e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase MgtC PF02308.16 ABK72376.1 - 0.4 11.1 3.6 0.1 12.9 0.5 1.5 2 0 0 2 2 2 0 MgtC family DAO PF01266.24 ABK72377.1 - 9.2e-47 160.3 11.2 1.1e-46 160.0 11.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ABK72377.1 - 0.0057 15.9 0.0 0.018 14.3 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 ABK72377.1 - 0.031 14.2 2.4 0.033 14.1 0.6 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 ABK72377.1 - 0.16 11.3 0.1 0.39 10.0 0.2 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CMD PF02627.20 ABK72378.1 - 3e-10 40.0 1.2 8.7e-09 35.3 0.0 2.8 3 1 0 3 3 3 2 Carboxymuconolactone decarboxylase family zf-HC2 PF13490.6 ABK72380.1 - 0.0012 19.1 2.6 0.0023 18.1 2.6 1.5 1 0 0 1 1 1 1 Putative zinc-finger AMP-binding PF00501.28 ABK72382.1 - 2.2e-88 296.7 0.0 2.6e-88 296.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK72382.1 - 2.7e-18 66.7 0.0 8.1e-18 65.2 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF4124 PF13511.6 ABK72382.1 - 0.055 13.8 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4124) TAL_FSA PF00923.19 ABK72383.1 - 4.1e-84 282.3 0.2 4.6e-84 282.1 0.2 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase NolV PF06635.12 ABK72383.1 - 0.059 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein NolV MaoC_dehydrat_N PF13452.6 ABK72384.1 - 0.009 16.1 0.2 0.089 12.9 0.2 2.0 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase adh_short PF00106.25 ABK72385.1 - 2.1e-41 141.5 13.4 4.6e-41 140.4 13.4 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK72385.1 - 2.5e-38 131.9 16.9 5.8e-38 130.8 16.9 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK72385.1 - 4.2e-14 52.8 7.9 8.1e-14 51.9 7.9 1.5 1 1 0 1 1 1 1 KR domain DUF4170 PF13773.6 ABK72385.1 - 0.0042 17.2 0.2 0.011 15.8 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4170) DAHP_synth_1 PF00793.20 ABK72386.1 - 1.8e-98 328.8 0.0 2.1e-98 328.5 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family ABC_tran PF00005.27 ABK72388.1 - 1e-29 103.8 0.0 1.6e-29 103.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SIP PF04954.13 ABK72388.1 - 3.3e-24 85.7 0.1 6.6e-24 84.7 0.1 1.5 1 0 0 1 1 1 1 Siderophore-interacting protein ABC_membrane PF00664.23 ABK72388.1 - 2.8e-15 56.7 6.2 4.6e-15 56.0 6.2 1.4 1 1 0 1 1 1 1 ABC transporter transmembrane region FAD_binding_9 PF08021.11 ABK72388.1 - 5.1e-15 55.7 0.0 3.3e-13 49.9 0.0 2.6 1 1 0 1 1 1 1 Siderophore-interacting FAD-binding domain SMC_N PF02463.19 ABK72388.1 - 2.5e-07 30.4 0.1 0.00029 20.3 0.0 2.2 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ABK72388.1 - 2.2e-05 24.8 0.1 0.00021 21.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ABK72388.1 - 5.7e-05 23.6 1.6 0.00019 21.8 0.7 2.3 3 0 0 3 3 2 1 AAA ATPase domain AAA_24 PF13479.6 ABK72388.1 - 0.00019 21.2 0.0 0.00034 20.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ABK72388.1 - 0.00097 18.8 0.1 0.0027 17.4 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ABK72388.1 - 0.0022 17.9 0.0 0.0045 16.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 ABK72388.1 - 0.0023 17.8 0.1 0.017 14.9 0.0 2.0 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 ABK72388.1 - 0.0044 16.6 0.2 0.023 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ABK72388.1 - 0.0062 16.7 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 ABK72388.1 - 0.018 14.3 0.0 0.046 13.0 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 ABK72388.1 - 0.021 14.5 0.4 0.063 13.0 0.4 1.8 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 ABK72388.1 - 0.031 14.2 0.1 0.056 13.3 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.6 ABK72388.1 - 0.049 14.2 0.0 0.098 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 ABK72388.1 - 0.051 12.4 0.1 0.66 8.7 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Cytidylate_kin PF02224.18 ABK72388.1 - 0.063 13.0 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase AAA PF00004.29 ABK72388.1 - 0.11 12.9 0.1 0.85 10.1 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ABK72388.1 - 0.11 12.5 0.1 0.32 11.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 ABK72388.1 - 0.13 12.0 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 ABK72388.1 - 0.23 11.9 0.0 0.37 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain E1-E2_ATPase PF00122.20 ABK72389.1 - 7.4e-41 139.6 0.3 7.4e-41 139.6 0.3 3.0 3 1 1 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 ABK72389.1 - 8.6e-17 62.1 0.3 1.6e-16 61.2 0.3 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 ABK72389.1 - 0.0001 22.1 11.7 0.0001 22.1 11.7 2.9 2 1 1 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.12 ABK72389.1 - 0.00036 20.4 0.2 0.00067 19.5 0.2 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF454 PF04304.13 ABK72389.1 - 0.043 13.8 6.2 0.22 11.5 1.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF454) gp12-short_mid PF09089.10 ABK72390.1 - 0.026 14.7 1.1 0.042 14.0 0.7 1.6 1 1 1 2 2 2 0 Phage short tail fibre protein gp12, middle domain Senescence PF06911.12 ABK72390.1 - 1.5 9.1 9.2 0.085 13.2 4.1 1.6 2 0 0 2 2 2 0 Senescence-associated protein MarR_2 PF12802.7 ABK72391.1 - 4.9e-11 42.4 1.7 5.9e-11 42.1 0.5 1.7 2 0 0 2 2 2 1 MarR family MarR PF01047.22 ABK72391.1 - 2.1e-09 37.2 0.0 3.6e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 ABK72391.1 - 6.6e-07 29.7 0.0 1.2e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_20 PF12840.7 ABK72391.1 - 0.00014 21.8 0.3 0.00032 20.7 0.3 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 ABK72391.1 - 0.00023 20.9 0.1 0.00065 19.5 0.1 1.8 1 1 1 2 2 2 1 IclR helix-turn-helix domain TrmB PF01978.19 ABK72391.1 - 0.00057 19.7 0.0 0.013 15.4 0.0 2.1 1 1 1 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.20 ABK72391.1 - 0.0071 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_1 PF00126.27 ABK72391.1 - 0.014 15.3 0.1 0.04 13.9 0.1 1.9 1 1 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family DUF742 PF05331.11 ABK72391.1 - 0.025 14.4 0.3 0.044 13.6 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF742) DprA_WH PF17782.1 ABK72391.1 - 0.025 14.7 7.3 0.052 13.7 0.2 3.6 3 1 1 4 4 4 0 DprA winged helix domain HTH_24 PF13412.6 ABK72391.1 - 0.072 12.7 0.0 0.18 11.4 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_34 PF13601.6 ABK72391.1 - 0.18 12.0 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain PE-PPE PF08237.11 ABK72392.1 - 3.1e-07 30.2 7.4 0.00018 21.1 0.1 3.0 3 1 0 3 3 3 2 PE-PPE domain DUF948 PF06103.11 ABK72392.1 - 3 8.1 7.7 16 5.9 0.0 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Nitroreductase PF00881.24 ABK72393.1 - 7.3e-26 91.2 1.5 2.7e-25 89.4 1.5 2.0 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 ABK72393.1 - 0.0015 18.1 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 2 Putative TM nitroreductase LPD22 PF18834.1 ABK72393.1 - 0.09 13.0 3.9 5.9 7.2 1.3 3.2 2 1 1 3 3 3 0 Large polyvalent protein associated domain 22 TetR_N PF00440.23 ABK72395.1 - 6e-14 51.6 1.3 1e-13 50.9 1.3 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_7 PF02796.15 ABK72395.1 - 0.0014 18.7 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_Tnp_1_2 PF13022.6 ABK72395.1 - 0.0026 17.9 0.0 0.0041 17.3 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix of insertion element transposase HTH_23 PF13384.6 ABK72395.1 - 0.0082 15.9 0.0 0.025 14.4 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_IclR PF09339.10 ABK72395.1 - 0.032 14.0 0.0 0.097 12.5 0.0 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_22 PF13309.6 ABK72395.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 HTH domain HTH_6 PF01418.17 ABK72395.1 - 0.15 12.1 0.0 4.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family Glyoxalase_3 PF13468.6 ABK72396.1 - 0.00031 20.9 0.2 0.57 10.3 0.0 3.1 2 1 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_4 PF13669.6 ABK72396.1 - 0.0047 17.2 0.0 0.009 16.3 0.0 1.5 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ATP-synt_Z PF16594.5 ABK72397.1 - 0.032 13.7 2.2 0.048 13.2 2.2 1.3 1 0 0 1 1 1 0 Putative AtpZ or ATP-synthase-associated SURF1 PF02104.15 ABK72397.1 - 0.21 11.8 5.3 3.6 7.8 1.6 2.4 1 1 1 2 2 2 0 SURF1 family AMP-binding PF00501.28 ABK72398.1 - 0 1800.7 12.5 3.8e-97 325.6 0.1 7.1 6 1 0 6 6 6 6 AMP-binding enzyme Condensation PF00668.20 ABK72398.1 - 0 1549.5 0.0 6.7e-85 285.5 0.0 8.1 8 0 0 8 8 8 8 Condensation domain AMP-binding_C PF13193.6 ABK72398.1 - 4.5e-84 277.5 11.5 1.2e-16 61.4 0.0 8.4 7 0 0 7 7 7 6 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 ABK72398.1 - 4.8e-78 257.5 14.3 1.1e-15 57.7 0.2 7.1 6 0 0 6 6 6 6 Phosphopantetheine attachment site Thioesterase PF00975.20 ABK72398.1 - 3.3e-28 99.4 0.0 8.2e-28 98.1 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain HicB PF05534.12 ABK72398.1 - 0.00051 19.8 0.0 0.81 9.6 0.0 2.6 2 0 0 2 2 2 2 HicB family CopD PF05425.13 ABK72399.1 - 4.7e-16 59.1 12.7 4.7e-16 59.1 12.7 4.4 2 1 1 4 4 4 1 Copper resistance protein D HlyIII PF03006.20 ABK72399.1 - 0.028 14.1 0.7 0.028 14.1 0.7 2.7 1 1 2 3 3 3 0 Haemolysin-III related HAD PF12710.7 ABK72400.1 - 7.1e-29 101.5 0.2 1.2e-28 100.8 0.2 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ACT_6 PF13740.6 ABK72400.1 - 9.3e-20 70.4 0.7 7.9e-18 64.2 0.5 2.8 2 0 0 2 2 2 1 ACT domain Hydrolase PF00702.26 ABK72400.1 - 1.9e-18 67.5 1.2 3.5e-18 66.7 1.2 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ABK72400.1 - 2.5e-13 50.4 0.0 2.6e-12 47.0 0.0 2.4 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase ACT PF01842.25 ABK72400.1 - 1.2e-07 31.3 1.0 0.00047 19.9 0.4 3.0 2 0 0 2 2 2 2 ACT domain S6PP PF05116.13 ABK72400.1 - 4.2e-06 26.5 0.0 6.4e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase HAD_2 PF13419.6 ABK72400.1 - 4.4e-06 26.9 0.0 0.00013 22.1 0.0 2.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 ABK72400.1 - 0.0028 17.1 0.0 0.094 12.1 0.0 2.1 2 0 0 2 2 2 1 Putative Phosphatase ACT_4 PF13291.6 ABK72400.1 - 0.056 14.0 0.0 0.85 10.3 0.0 2.4 2 0 0 2 2 2 0 ACT domain Hydrolase_like PF13242.6 ABK72400.1 - 0.12 12.4 2.9 0.48 10.5 0.1 2.6 2 0 0 2 2 2 0 HAD-hyrolase-like NTP_transf_5 PF14907.6 ABK72401.1 - 0.00012 21.8 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised nucleotidyltransferase DUF1543 PF07566.12 ABK72401.1 - 0.11 12.2 0.4 0.33 10.7 0.4 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1543) adh_short PF00106.25 ABK72402.1 - 1.9e-40 138.4 2.5 3.4e-40 137.6 2.5 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK72402.1 - 4.1e-34 118.2 2.1 1.1e-33 116.7 2.1 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK72402.1 - 3.5e-23 82.5 0.6 5e-23 81.9 0.6 1.1 1 0 0 1 1 1 1 KR domain HHH_8 PF14716.6 ABK72403.1 - 7.4e-14 51.9 0.0 1.6e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain PHP PF02811.19 ABK72403.1 - 1.5e-09 38.4 0.0 2e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 PHP domain HHH PF00633.23 ABK72403.1 - 0.00025 20.8 0.0 0.00057 19.6 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 ABK72403.1 - 0.0023 18.5 0.2 0.19 12.4 0.0 2.0 1 1 1 2 2 2 2 Helix-hairpin-helix domain RNase_P_p30 PF01876.16 ABK72403.1 - 0.19 11.2 0.0 0.33 10.4 0.0 1.5 1 1 0 1 1 1 0 RNase P subunit p30 OsmC PF02566.19 ABK72405.1 - 1.8e-15 57.2 0.0 5.1e-15 55.8 0.0 1.6 2 0 0 2 2 2 1 OsmC-like protein MFS_1 PF07690.16 ABK72406.1 - 5e-26 91.5 55.0 6e-25 87.9 39.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ABK72406.1 - 2.5e-05 23.7 48.4 3.1e-05 23.5 48.4 1.0 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB HTH_1 PF00126.27 ABK72407.1 - 6.5e-21 74.0 0.9 2e-20 72.5 0.9 1.9 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 ABK72407.1 - 8.1e-20 71.1 4.7 1.3e-19 70.4 4.7 1.2 1 0 0 1 1 1 1 LysR substrate binding domain MarR_2 PF12802.7 ABK72407.1 - 0.00069 19.4 1.0 0.012 15.5 0.2 2.9 3 0 0 3 3 3 1 MarR family Lambda_tail_I PF06805.12 ABK72407.1 - 0.028 14.8 0.1 0.17 12.2 0.1 2.1 2 0 0 2 2 2 0 Bacteriophage lambda tail assembly protein I HTH_IclR PF09339.10 ABK72407.1 - 0.033 14.0 0.4 0.97 9.3 0.1 2.7 2 0 0 2 2 2 0 IclR helix-turn-helix domain MarR PF01047.22 ABK72407.1 - 0.16 11.9 0.0 0.38 10.7 0.0 1.7 1 0 0 1 1 1 0 MarR family Ribosomal_L14 PF00238.19 ABK72408.1 - 3.1e-55 185.5 1.2 3.4e-55 185.4 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DUF730 PF05325.11 ABK72408.1 - 0.055 13.5 0.3 0.22 11.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF730) Toprim_2 PF13155.6 ABK72408.1 - 0.13 12.7 0.0 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 Toprim-like CoA_transf_3 PF02515.17 ABK72409.1 - 5e-116 387.8 0.0 5.7e-116 387.7 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Oxidored_q4 PF00507.19 ABK72410.1 - 1.3e-34 118.3 0.9 1.8e-34 117.8 0.9 1.2 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 DUF4282 PF14110.6 ABK72410.1 - 0.89 10.3 13.3 0.46 11.3 7.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) SnoaL_2 PF12680.7 ABK72412.1 - 4.4e-05 24.1 0.7 6e-05 23.6 0.7 1.4 1 1 0 1 1 1 1 SnoaL-like domain adh_short_C2 PF13561.6 ABK72413.1 - 3.8e-46 157.5 0.3 7e-46 156.7 0.3 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK72413.1 - 1.4e-35 122.5 0.2 6.8e-35 120.3 0.2 1.8 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 ABK72413.1 - 1.6e-08 34.3 0.0 8.1e-08 32.0 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ABK72413.1 - 5.3e-07 29.7 0.3 6.8e-07 29.4 0.3 1.2 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 ABK72413.1 - 5.1e-06 26.5 0.2 0.01 15.7 0.1 2.1 2 0 0 2 2 2 2 KR domain RmlD_sub_bind PF04321.17 ABK72413.1 - 0.051 12.7 0.0 0.099 11.7 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain GvpK PF05121.12 ABK72414.1 - 1.4e-36 124.4 5.3 1.5e-36 124.3 5.3 1.0 1 0 0 1 1 1 1 Gas vesicle protein K Glyco_hydro_15 PF00723.21 ABK72415.1 - 9.5e-54 182.9 0.0 2.3e-49 168.4 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 Thiolase_N PF00108.23 ABK72416.1 - 2.2e-59 200.9 0.0 3.5e-59 200.3 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ABK72416.1 - 3.2e-44 149.5 0.0 6.8e-44 148.5 0.0 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ABK72416.1 - 0.00012 21.8 1.9 0.0004 20.0 0.8 2.2 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 ABK72416.1 - 0.046 13.9 0.0 0.42 10.8 0.0 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DEAD PF00270.29 ABK72417.1 - 9.7e-50 168.8 0.0 1.5e-47 161.6 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 ABK72417.1 - 5.4e-31 107.2 0.1 3.3e-30 104.7 0.3 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DbpA PF03880.15 ABK72417.1 - 3.2e-21 75.1 0.0 7.6e-21 73.9 0.0 1.7 1 0 0 1 1 1 1 DbpA RNA binding domain ResIII PF04851.15 ABK72417.1 - 6.7e-06 26.2 0.0 2.5e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 ABK72417.1 - 0.0044 16.4 0.1 0.016 14.6 0.0 1.9 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit UvrA_inter PF17760.1 ABK72417.1 - 0.0064 16.6 0.2 0.037 14.1 0.1 2.2 2 0 0 2 2 2 1 UvrA interaction domain adh_short PF00106.25 ABK72417.1 - 0.088 12.3 0.3 0.17 11.3 0.3 1.4 1 0 0 1 1 1 0 short chain dehydrogenase DUF5036 PF16439.5 ABK72417.1 - 0.09 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5036) Flavi_DEAD PF07652.14 ABK72417.1 - 0.11 12.5 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 Flavivirus DEAD domain DUF222 PF02720.17 ABK72418.1 - 5.4e-56 190.3 4.0 9.1e-56 189.5 4.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF222) TetR_C_21 PF17926.1 ABK72418.1 - 0.068 13.3 0.0 0.23 11.6 0.0 1.9 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain adh_short PF00106.25 ABK72419.1 - 3.9e-52 176.6 0.1 5.7e-52 176.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK72419.1 - 6.1e-42 143.8 0.0 8.7e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK72419.1 - 7.7e-12 45.5 0.0 1.1e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK72419.1 - 0.00034 20.2 0.1 0.00057 19.4 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 ABK72419.1 - 0.022 14.2 1.5 1.3 8.4 1.3 2.2 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 ABK72420.1 - 5.4e-58 196.3 0.8 6.2e-58 196.1 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK72420.1 - 1.1e-40 139.2 0.0 1.3e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK72420.1 - 3.3e-11 43.4 0.8 4.9e-11 42.9 0.8 1.2 1 0 0 1 1 1 1 KR domain TetR_N PF00440.23 ABK72421.1 - 7.8e-11 41.6 1.1 2.1e-10 40.2 0.4 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_20 PF17925.1 ABK72421.1 - 8.2e-08 32.5 0.9 1.2e-07 31.9 0.1 1.7 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_16 PF17920.1 ABK72421.1 - 0.095 12.9 1.6 0.11 12.8 0.3 1.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TetR_C_24 PF17932.1 ABK72421.1 - 0.11 12.8 0.5 2.5 8.4 0.1 2.4 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Glyco_trans_1_4 PF13692.6 ABK72422.1 - 1.8e-33 115.8 0.3 1e-32 113.4 0.2 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 ABK72422.1 - 8.3e-29 100.3 0.0 1.2e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ABK72422.1 - 1.1e-25 90.6 0.2 2e-25 89.8 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 ABK72422.1 - 5.7e-15 56.1 1.1 5.7e-15 56.1 1.1 2.4 1 1 1 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 ABK72422.1 - 1.9e-08 34.6 0.1 1.6e-07 31.6 0.0 2.4 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 ABK72422.1 - 7.2e-08 32.6 0.0 1.7e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_transf_5 PF08323.11 ABK72422.1 - 0.063 13.0 0.6 0.29 10.8 0.2 2.1 2 1 0 2 2 2 0 Starch synthase catalytic domain DUF4185 PF13810.6 ABK72424.1 - 6.8e-94 314.6 6.9 9.3e-94 314.2 6.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) AF-4 PF05110.13 ABK72424.1 - 0.0004 18.6 10.5 0.00055 18.2 10.5 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Glyco_hydro_43 PF04616.14 ABK72424.1 - 0.033 13.5 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 43 CCSAP PF15748.5 ABK72424.1 - 3.8 7.6 12.1 6 7.0 12.1 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated LemA PF04011.12 ABK72425.1 - 9.8e-41 139.1 0.1 1.2e-40 138.8 0.1 1.1 1 0 0 1 1 1 1 LemA family ABC_tran PF00005.27 ABK72426.1 - 2.2e-30 105.9 0.0 3.1e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK72426.1 - 2.1e-09 37.6 0.0 0.0014 18.5 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK72426.1 - 6.7e-05 22.4 0.0 0.17 11.3 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ABK72426.1 - 0.00018 21.8 0.0 0.00039 20.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 ABK72426.1 - 0.00061 19.8 0.0 0.00098 19.1 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_29 PF13555.6 ABK72426.1 - 0.00083 19.1 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 ABK72426.1 - 0.0012 19.2 0.2 0.012 16.0 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 ABK72426.1 - 0.0015 18.2 0.1 0.0088 15.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ABK72426.1 - 0.0022 17.9 0.0 0.0041 17.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 ABK72426.1 - 0.0076 16.0 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 ABK72426.1 - 0.0091 16.2 0.0 0.016 15.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ABK72426.1 - 0.023 15.2 0.0 0.045 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ABK72426.1 - 0.057 13.9 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ABK72426.1 - 0.059 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 ABK72426.1 - 0.063 13.7 0.1 1.5 9.3 0.0 2.7 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) PRK PF00485.18 ABK72426.1 - 0.065 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Adeno_IVa2 PF02456.15 ABK72426.1 - 0.23 10.2 0.0 1.1 8.0 0.0 1.8 2 0 0 2 2 2 0 Adenovirus IVa2 protein Glft2_N PF17994.1 ABK72427.1 - 2.7e-65 218.6 0.0 4.9e-65 217.7 0.0 1.4 1 0 0 1 1 1 1 Galactofuranosyltransferase 2 N-terminal Glyco_tranf_2_3 PF13641.6 ABK72427.1 - 4e-50 170.9 0.0 7.4e-50 170.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 ABK72427.1 - 9.1e-05 22.3 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 PglD_N PF17836.1 ABK72427.1 - 0.19 12.4 0.0 0.42 11.3 0.0 1.5 1 0 0 1 1 1 0 PglD N-terminal domain Glyco_trans_2_3 PF13632.6 ABK72427.1 - 0.54 10.1 2.9 6.1 6.7 0.1 2.6 3 0 0 3 3 3 0 Glycosyl transferase family group 2 TetR_N PF00440.23 ABK72428.1 - 1.4e-06 28.0 0.0 5e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 ABK72428.1 - 2.5e-06 27.7 0.4 2.5e-06 27.7 0.4 1.8 2 0 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal HTH_Tnp_IS630 PF01710.16 ABK72428.1 - 0.18 11.8 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 Transposase Abhydrolase_6 PF12697.7 ABK72429.1 - 2.1e-09 38.3 6.8 1.7e-08 35.4 6.8 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK72429.1 - 6.1e-09 35.5 0.0 0.00037 19.8 0.0 2.4 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ABK72429.1 - 1.4e-05 24.9 0.2 0.00038 20.2 0.1 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ABK72429.1 - 0.0002 20.9 0.1 0.049 13.1 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family TetR_N PF00440.23 ABK72430.1 - 2.2e-16 59.4 1.9 3e-16 59.0 0.7 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 ABK72430.1 - 0.031 14.5 0.1 0.21 11.8 0.0 2.1 2 1 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal DUF3493 PF11998.8 ABK72430.1 - 0.084 13.1 0.2 0.22 11.7 0.2 1.6 1 0 0 1 1 1 0 Low psii accumulation1 / Rep27 RsgA_GTPase PF03193.16 ABK72430.1 - 0.15 11.9 0.1 1 9.2 0.1 2.1 1 1 0 1 1 1 0 RsgA GTPase SBP_bac_3 PF00497.20 ABK72431.1 - 1.6e-54 184.7 0.3 1.8e-54 184.5 0.3 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 ABK72431.1 - 0.00016 21.8 0.0 0.00051 20.2 0.0 1.8 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Phosphonate-bd PF12974.7 ABK72431.1 - 0.0017 18.0 0.1 0.0079 15.8 0.1 2.0 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein Aldedh PF00171.22 ABK72432.1 - 5.4e-162 539.5 0.0 6.2e-162 539.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 ABK72432.1 - 0.072 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) OmdA PF13376.6 ABK72432.1 - 0.1 12.6 0.4 0.21 11.6 0.4 1.5 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated TetR_N PF00440.23 ABK72433.1 - 9.2e-15 54.2 0.6 4.2e-06 26.4 0.1 2.5 2 0 0 2 2 2 2 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 ABK72433.1 - 6e-08 33.0 2.4 6e-08 33.0 2.4 2.3 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain HTH_7 PF02796.15 ABK72433.1 - 0.0025 17.8 0.0 3.3 7.8 0.0 2.7 2 0 0 2 2 2 2 Helix-turn-helix domain of resolvase Phage_AlpA PF05930.12 ABK72433.1 - 0.0084 15.9 0.2 5.7 6.8 0.0 2.5 2 0 0 2 2 2 2 Prophage CP4-57 regulatory protein (AlpA) NTPase_1 PF03266.15 ABK72433.1 - 0.011 15.7 0.0 5.3 6.9 0.0 2.2 2 0 0 2 2 2 0 NTPase HTH_psq PF05225.16 ABK72433.1 - 0.019 14.7 1.2 10 6.0 0.1 3.1 3 0 0 3 3 3 0 helix-turn-helix, Psq domain HTH_10 PF04967.12 ABK72433.1 - 0.02 14.7 0.1 12 5.8 0.0 2.8 3 0 0 3 3 3 0 HTH DNA binding domain MamL-1 PF09596.10 ABK72433.1 - 0.032 14.5 0.5 11 6.3 0.0 2.8 2 0 0 2 2 2 0 MamL-1 domain TrmB PF01978.19 ABK72433.1 - 0.046 13.6 0.0 14 5.7 0.0 2.3 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB TetR_C_6 PF13977.6 ABK72433.1 - 0.062 13.5 8.3 2.4 8.4 0.2 3.6 4 1 0 4 4 4 0 BetI-type transcriptional repressor, C-terminal HTH_IclR PF09339.10 ABK72433.1 - 0.36 10.7 2.8 20 5.1 0.2 2.7 2 0 0 2 2 2 0 IclR helix-turn-helix domain CaM_bdg_C0 PF10562.9 ABK72433.1 - 5.6 7.1 6.4 27 4.9 0.7 2.4 2 0 0 2 2 2 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit GntR PF00392.21 ABK72434.1 - 7e-10 38.4 0.1 1.3e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family FCD PF07729.12 ABK72434.1 - 0.0011 19.4 0.5 0.0074 16.7 0.3 2.3 1 1 1 2 2 2 1 FCD domain HTH_41 PF14502.6 ABK72434.1 - 0.01 15.5 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain YceI PF04264.13 ABK72435.1 - 3.2e-44 151.0 0.3 3.7e-44 150.8 0.3 1.0 1 0 0 1 1 1 1 YceI-like domain Redoxin PF08534.10 ABK72436.1 - 4.8e-12 45.8 0.0 5.5e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 ABK72436.1 - 1e-11 44.8 0.0 1.5e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 ABK72436.1 - 1.5e-06 28.5 0.0 2e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 ABK72436.1 - 6.9e-05 22.8 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 ABK72436.1 - 0.004 16.9 0.0 0.0059 16.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DUF2749 PF10907.8 ABK72436.1 - 0.094 12.9 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) SBP_bac_3 PF00497.20 ABK72437.1 - 3e-61 206.7 2.4 4e-61 206.3 2.4 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 BPD_transp_1 PF00528.22 ABK72437.1 - 5.1e-24 85.0 10.1 5.1e-24 85.0 10.1 2.1 1 1 1 2 2 2 2 Binding-protein-dependent transport system inner membrane component Phosphonate-bd PF12974.7 ABK72437.1 - 0.00026 20.7 0.5 0.013 15.1 1.0 2.9 2 1 0 2 2 2 1 ABC transporter, phosphonate, periplasmic substrate-binding protein Lig_chan-Glu_bd PF10613.9 ABK72437.1 - 0.00047 20.3 0.0 0.0077 16.4 0.0 2.3 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site NMT1 PF09084.11 ABK72437.1 - 0.0025 17.8 0.9 0.0076 16.2 0.1 2.0 2 1 1 3 3 3 2 NMT1/THI5 like MFS_1 PF07690.16 ABK72438.1 - 5.3e-38 130.9 53.7 6e-27 94.5 41.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK72438.1 - 7e-14 51.5 12.9 7e-14 51.5 12.9 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter PUCC PF03209.15 ABK72438.1 - 1e-05 24.8 34.0 0.0006 18.9 12.9 2.7 2 1 0 2 2 2 2 PUCC protein DUF5423 PF17461.2 ABK72438.1 - 0.037 12.9 0.2 0.037 12.9 0.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5423) AP_endonuc_2 PF01261.24 ABK72439.1 - 6.3e-26 91.1 0.1 8.1e-26 90.8 0.1 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel AA_permease_2 PF13520.6 ABK72440.1 - 3e-30 105.4 52.8 3.9e-30 105.0 52.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ABK72440.1 - 1.4e-28 99.8 41.4 1.4e-28 99.8 41.4 1.7 1 1 1 2 2 2 1 Amino acid permease ATP-grasp PF02222.22 ABK72441.1 - 3.4e-52 176.5 0.0 4.7e-52 176.0 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 ABK72441.1 - 4.3e-14 51.9 0.1 9e-14 50.9 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 ABK72441.1 - 0.00064 19.3 0.1 0.0021 17.6 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.19 ABK72441.1 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Peptidase_M24 PF00557.24 ABK72442.1 - 2e-43 148.5 0.0 2.3e-43 148.3 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 Thiolase_N PF00108.23 ABK72443.1 - 1.3e-72 244.3 0.7 1.8e-72 243.9 0.7 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ABK72443.1 - 5.1e-43 145.6 0.2 9.1e-43 144.8 0.2 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ABK72443.1 - 0.00015 21.5 1.3 0.00049 19.7 1.2 2.0 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain MoCF_biosynth PF00994.24 ABK72445.1 - 1.1e-29 102.9 0.1 1.4e-29 102.7 0.1 1.0 1 0 0 1 1 1 1 Probable molybdopterin binding domain HTH_18 PF12833.7 ABK72446.1 - 2.3e-21 75.8 0.9 4.3e-21 75.0 0.9 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 ABK72446.1 - 3e-19 68.6 0.0 1.7e-08 34.4 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family DJ-1_PfpI PF01965.24 ABK72446.1 - 1.3e-13 51.1 0.0 2e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family LisH_TPL PF17814.1 ABK72446.1 - 0.099 12.3 0.5 0.18 11.5 0.5 1.3 1 0 0 1 1 1 0 LisH-like dimerisation domain SnoaL_2 PF12680.7 ABK72447.1 - 2.2e-05 25.0 0.1 3.4e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 ABK72447.1 - 0.034 14.4 0.2 0.049 13.9 0.2 1.3 1 0 0 1 1 1 0 SnoaL-like domain Linocin_M18 PF04454.12 ABK72448.1 - 1.6e-95 319.2 0.0 1.8e-95 319.0 0.0 1.0 1 0 0 1 1 1 1 Encapsulating protein for peroxidase Ycf4 PF02392.16 ABK72449.1 - 0.07 12.7 0.1 0.082 12.5 0.1 1.0 1 0 0 1 1 1 0 Ycf4 Fapy_DNA_glyco PF01149.24 ABK72450.1 - 6.3e-36 123.5 0.3 1.3e-35 122.5 0.1 1.6 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 ABK72450.1 - 3.2e-24 84.7 0.0 5.3e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain zf-FPG_IleRS PF06827.14 ABK72450.1 - 9.3e-12 44.6 5.3 2e-11 43.5 5.3 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS Auto_anti-p27 PF06677.12 ABK72450.1 - 0.011 15.9 1.8 0.023 14.9 1.8 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) TackOD1 PF18551.1 ABK72450.1 - 0.023 14.4 0.2 0.033 13.9 0.2 1.2 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 FbpA PF05833.11 ABK72450.1 - 0.03 13.1 0.0 0.039 12.7 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) OrfB_Zn_ribbon PF07282.11 ABK72450.1 - 0.54 10.2 1.6 1.2 9.2 1.6 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain MlaE PF02405.16 ABK72451.1 - 6.5e-58 195.9 23.5 7.7e-58 195.6 23.5 1.1 1 0 0 1 1 1 1 Permease MlaE BPD_transp_2 PF02653.16 ABK72452.1 - 1.7e-47 161.8 29.3 2.2e-47 161.5 29.3 1.1 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component MspA PF09203.11 ABK72453.1 - 3.7e-41 140.9 0.5 4.4e-41 140.6 0.5 1.1 1 0 0 1 1 1 1 MspA Fer4_15 PF13459.6 ABK72454.1 - 2.7e-11 44.0 0.5 3.2e-11 43.8 0.5 1.1 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_13 PF13370.6 ABK72454.1 - 7.6e-10 39.2 0.0 9.1e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_19 PF06902.11 ABK72454.1 - 8.5e-08 32.2 0.0 1.1e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Divergent 4Fe-4S mono-cluster PhnA_Zn_Ribbon PF08274.12 ABK72455.1 - 0.042 13.8 0.2 0.15 12.0 0.2 1.9 1 0 0 1 1 1 0 PhnA Zinc-Ribbon zinc-ribbons_6 PF07191.12 ABK72455.1 - 0.65 10.0 4.2 2.1 8.4 1.9 2.5 2 0 0 2 2 2 0 zinc-ribbons SnoaL_2 PF12680.7 ABK72456.1 - 0.12 13.1 0.1 0.19 12.4 0.1 1.3 1 0 0 1 1 1 0 SnoaL-like domain LysR_substrate PF03466.20 ABK72458.1 - 5.5e-30 104.3 5.2 7.7e-30 103.8 5.2 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 ABK72458.1 - 1.6e-16 60.0 0.3 4.6e-16 58.5 0.3 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family ABC_tran PF00005.27 ABK72459.1 - 1.4e-24 87.2 0.0 2.7e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK72459.1 - 7.4e-13 49.0 0.3 3.3e-06 27.1 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK72459.1 - 4.6e-09 36.0 0.0 0.00038 20.0 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ABK72459.1 - 9.9e-05 22.9 0.0 0.00016 22.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ABK72459.1 - 0.0002 21.0 0.0 0.00046 19.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 ABK72459.1 - 0.00034 21.0 0.0 0.0033 17.8 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 ABK72459.1 - 0.00058 19.7 0.0 0.18 11.5 0.0 2.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_16 PF13191.6 ABK72459.1 - 0.0027 18.1 2.0 0.0097 16.3 2.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ABK72459.1 - 0.0029 17.9 1.2 0.048 13.9 1.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ABK72459.1 - 0.0036 17.1 0.2 0.0072 16.1 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_27 PF13514.6 ABK72459.1 - 0.015 14.9 0.0 0.039 13.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 ABK72459.1 - 0.02 15.2 0.0 0.04 14.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ABK72459.1 - 0.051 13.1 0.1 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 ABK72459.1 - 0.054 13.4 0.0 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_14 PF13173.6 ABK72459.1 - 0.057 13.5 0.0 0.48 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 ABK72459.1 - 0.067 13.4 0.2 0.53 10.6 0.2 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 ABK72459.1 - 0.098 12.6 0.4 0.19 11.6 0.4 1.8 1 1 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 ABK72459.1 - 0.11 12.4 0.1 0.42 10.5 0.1 1.8 2 0 0 2 2 2 0 NTPase Rad17 PF03215.15 ABK72459.1 - 0.21 11.5 0.1 0.39 10.6 0.1 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain ATPase_2 PF01637.18 ABK72459.1 - 0.25 11.2 0.0 0.42 10.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_13 PF13166.6 ABK72459.1 - 0.29 9.7 0.0 6.2 5.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain OB_aCoA_assoc PF01796.17 ABK72460.1 - 4.3e-28 97.1 3.7 9.9e-14 51.1 0.1 2.5 2 0 0 2 2 2 2 DUF35 OB-fold domain, acyl-CoA-associated DUF35_N PF12172.8 ABK72460.1 - 0.26 11.2 1.0 13 5.8 0.1 3.0 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) EPSP_synthase PF00275.20 ABK72461.1 - 5.6e-115 384.4 0.1 6.3e-115 384.2 0.1 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) BPD_transp_1 PF00528.22 ABK72462.1 - 1.3e-10 41.3 20.9 1.3e-10 41.3 20.9 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component adh_short_C2 PF13561.6 ABK72463.1 - 7e-29 101.0 0.2 9e-29 100.7 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK72463.1 - 3e-20 72.5 0.0 4.2e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK72463.1 - 0.0037 17.2 0.2 0.0057 16.6 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK72463.1 - 0.18 11.3 0.1 0.29 10.5 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family G6PD_C PF02781.16 ABK72464.1 - 8.1e-116 386.3 0.0 9.7e-116 386.0 0.0 1.0 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 ABK72464.1 - 3.5e-53 180.9 0.0 5.7e-53 180.2 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain MTHFR PF02219.17 ABK72465.1 - 0.2 10.9 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 Methylenetetrahydrofolate reductase PfkB PF00294.24 ABK72466.1 - 3.3e-54 184.3 0.0 3.7e-54 184.1 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Peripla_BP_3 PF13377.6 ABK72467.1 - 3.8e-29 102.2 1.6 1.9e-28 99.9 0.9 2.1 2 0 0 2 2 2 1 Periplasmic binding protein-like domain LacI PF00356.21 ABK72467.1 - 3.2e-17 62.0 3.4 1.3e-16 60.1 1.5 2.4 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family Peripla_BP_1 PF00532.21 ABK72467.1 - 6e-07 29.2 0.3 8.9e-07 28.6 0.3 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 ABK72467.1 - 1.3e-05 24.9 0.6 5.3e-05 22.9 0.3 1.9 2 0 0 2 2 2 1 Periplasmic binding protein domain HTH_31 PF13560.6 ABK72467.1 - 0.019 15.3 1.1 0.062 13.6 1.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 ABK72467.1 - 0.079 12.9 0.1 0.6 10.1 0.1 2.4 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain rve PF00665.26 ABK72468.1 - 1.1e-30 106.3 0.0 2.2e-30 105.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 ABK72468.1 - 4.5e-19 68.0 2.6 4.5e-19 68.0 2.6 2.0 2 0 0 2 2 1 1 Integrase core domain LZ_Tnp_IS481 PF13011.6 ABK72468.1 - 5.9e-15 55.6 3.7 5.9e-15 55.6 3.7 2.6 1 1 1 2 2 2 1 leucine-zipper of insertion element IS481 HTH_23 PF13384.6 ABK72468.1 - 3.2e-12 45.9 11.3 4.3e-10 39.1 0.5 3.3 3 0 0 3 3 3 2 Homeodomain-like domain HTH_32 PF13565.6 ABK72468.1 - 9.4e-12 45.4 1.9 9.4e-12 45.4 1.9 4.1 4 1 1 5 5 5 1 Homeodomain-like domain HTH_29 PF13551.6 ABK72468.1 - 2.1e-10 40.5 8.9 8.7e-09 35.3 0.3 2.8 3 0 0 3 3 3 2 Winged helix-turn helix HTH_28 PF13518.6 ABK72468.1 - 6.2e-10 39.0 0.5 6.2e-10 39.0 0.5 3.4 4 0 0 4 4 4 1 Helix-turn-helix domain Terminase_5 PF06056.12 ABK72468.1 - 3.2e-06 26.9 1.9 0.027 14.4 0.2 2.8 3 0 0 3 3 3 2 Putative ATPase subunit of terminase (gpP-like) HTH_Tnp_4 PF13613.6 ABK72468.1 - 7.5e-05 22.4 0.3 0.0039 16.9 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix of DDE superfamily endonuclease HTH_38 PF13936.6 ABK72468.1 - 0.0059 16.3 2.5 0.27 11.0 1.1 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 ABK72468.1 - 0.018 14.4 4.3 0.66 9.4 0.5 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_31 PF13560.6 ABK72468.1 - 0.033 14.5 1.2 0.033 14.5 1.2 2.8 2 1 0 2 2 2 0 Helix-turn-helix domain Trp_repressor PF01371.19 ABK72468.1 - 0.072 13.2 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Trp repressor protein HTH_50 PF18024.1 ABK72468.1 - 0.092 12.4 0.5 2.1 8.0 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.7 ABK72468.1 - 0.12 12.5 2.0 12 6.2 0.1 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain Sacchrp_dh_NADP PF03435.18 ABK72469.1 - 1.3e-12 48.1 0.1 2.1e-12 47.4 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 ABK72469.1 - 0.01 15.7 1.3 0.02 14.8 1.3 1.5 1 0 0 1 1 1 0 NAD(P)H-binding GDC-P PF02347.16 ABK72470.1 - 5.5e-197 654.8 0.0 2.7e-183 609.7 0.0 2.4 3 0 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 ABK72470.1 - 2.2e-06 26.9 0.5 3.7e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 ABK72470.1 - 0.00027 20.3 0.0 0.00072 18.9 0.0 1.7 1 0 0 1 1 1 1 Beta-eliminating lyase Trypan_glycop PF00913.19 ABK72470.1 - 0.0083 15.4 0.0 0.017 14.4 0.0 1.5 1 0 0 1 1 1 1 Trypanosome variant surface glycoprotein (A-type) Cys_Met_Meta_PP PF01053.20 ABK72470.1 - 0.017 13.7 0.3 1.1 7.7 0.2 2.6 2 1 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 ABK72470.1 - 0.08 12.1 0.0 0.18 11.0 0.0 1.6 1 0 0 1 1 1 0 Aminotransferase class I and II BPD_transp_1 PF00528.22 ABK72471.1 - 1.6e-25 89.9 12.8 1.6e-25 89.9 12.8 1.7 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DNA_pol3_delta PF06144.13 ABK72472.1 - 4.5e-07 29.8 0.0 6.2e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase III, delta subunit HEM4 PF02602.15 ABK72472.1 - 0.0045 16.4 1.5 0.0075 15.6 1.5 1.4 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD AA_kinase PF00696.28 ABK72472.1 - 0.0066 16.1 0.5 0.013 15.1 0.5 1.5 1 0 0 1 1 1 1 Amino acid kinase family Peptidase_M48 PF01435.18 ABK72473.1 - 1.9e-11 44.1 0.0 8.2e-11 42.0 0.0 1.9 1 1 1 2 2 2 1 Peptidase family M48 Peptidase_M56 PF05569.11 ABK72473.1 - 1.5e-06 27.7 0.3 3.4e-06 26.5 0.2 1.6 1 1 0 1 1 1 1 BlaR1 peptidase M56 DUF997 PF06196.12 ABK72473.1 - 1.6 8.8 4.9 0.24 11.4 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF997) Abhydrolase_6 PF12697.7 ABK72475.1 - 2.6e-22 80.5 9.4 3.1e-22 80.3 9.4 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ABK72475.1 - 4.2e-13 49.5 0.0 6.6e-12 45.6 0.1 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ABK72475.1 - 6.4e-08 32.2 0.0 1.2e-07 31.2 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 ABK72475.1 - 2.8e-06 27.6 0.0 4e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 ABK72475.1 - 2.4e-05 24.1 0.0 2.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Putative esterase DUF5473 PF17567.2 ABK72475.1 - 0.03 14.6 0.0 0.063 13.6 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5473) FSH1 PF03959.13 ABK72475.1 - 0.039 13.6 0.0 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Esterase_phd PF10503.9 ABK72475.1 - 0.12 11.8 0.6 0.2 11.1 0.1 1.6 2 0 0 2 2 2 0 Esterase PHB depolymerase DLH PF01738.18 ABK72475.1 - 0.17 11.4 0.0 0.68 9.4 0.0 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family Lipase_3 PF01764.25 ABK72475.1 - 0.18 11.7 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF4126 PF13548.6 ABK72476.1 - 1.5e-07 31.3 16.8 1.9e-07 31.0 16.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4126) MmgE_PrpD PF03972.14 ABK72476.1 - 0.0044 15.6 2.9 0.0057 15.3 2.9 1.1 1 0 0 1 1 1 1 MmgE/PrpD family Rick_17kDa_Anti PF05433.15 ABK72476.1 - 0.0062 16.4 15.1 0.0062 16.4 15.1 2.6 3 0 0 3 3 3 1 Glycine zipper 2TM domain TraT PF05818.12 ABK72476.1 - 4.2 7.0 6.6 0.2 11.3 1.4 1.5 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein Mak_N_cap PF18085.1 ABK72477.1 - 3.1e-14 53.8 0.5 8.2e-14 52.4 0.5 1.8 1 0 0 1 1 1 1 Maltokinase N-terminal cap domain APH PF01636.23 ABK72477.1 - 4e-06 26.9 3.6 1.4e-05 25.1 3.2 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family APH_6_hur PF04655.14 ABK72477.1 - 0.00096 18.6 0.7 0.0029 17.0 0.1 1.8 1 1 0 2 2 2 1 Aminoglycoside/hydroxyurea antibiotic resistance kinase Bd3614-deam PF14439.6 ABK72477.1 - 0.04 14.0 0.1 0.077 13.1 0.1 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase adh_short_C2 PF13561.6 ABK72478.1 - 4.2e-62 209.8 3.2 5e-62 209.5 3.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK72478.1 - 9.1e-46 155.8 0.8 1.3e-45 155.3 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK72478.1 - 7.9e-13 48.7 1.3 1.1e-12 48.2 1.3 1.1 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 ABK72478.1 - 1.3e-06 28.7 0.1 1.7e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 ABK72478.1 - 3.4e-06 26.7 0.1 4.9e-06 26.2 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 ABK72478.1 - 1.9e-05 24.6 0.5 4.3e-05 23.5 0.5 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase GDP_Man_Dehyd PF16363.5 ABK72478.1 - 0.00037 20.0 0.0 0.00077 19.0 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 ABK72478.1 - 0.00087 18.5 0.1 0.0013 17.9 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain ApbA PF02558.16 ABK72478.1 - 0.026 14.2 0.2 0.067 12.8 0.2 1.7 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 ABK72478.1 - 0.035 14.4 0.2 0.069 13.4 0.2 1.4 1 0 0 1 1 1 0 TrkA-N domain NUDIX PF00293.28 ABK72479.1 - 2.6e-15 56.6 0.7 4.1e-15 56.0 0.7 1.3 1 0 0 1 1 1 1 NUDIX domain SBP_bac_1 PF01547.25 ABK72480.1 - 8.1e-29 101.6 1.6 8.1e-29 101.6 1.6 1.7 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 ABK72480.1 - 1.1e-19 71.4 0.9 4.3e-19 69.4 0.9 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein UreF PF01730.16 ABK72481.1 - 2.7e-14 53.9 2.1 2.7e-14 53.9 2.1 1.4 1 1 0 1 1 1 1 UreF MDMPI_N PF11716.8 ABK72482.1 - 7.1e-07 30.0 8.8 9.6e-07 29.6 8.8 1.2 1 0 0 1 1 1 1 Mycothiol maleylpyruvate isomerase N-terminal domain DinB_2 PF12867.7 ABK72482.1 - 3.2e-06 27.7 1.6 4.3e-06 27.2 1.6 1.1 1 0 0 1 1 1 1 DinB superfamily Phage_integrase PF00589.22 ABK72483.1 - 4.4e-22 78.7 0.0 9.7e-22 77.6 0.0 1.6 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 ABK72483.1 - 7.4e-06 26.2 0.1 0.0011 19.2 0.0 3.1 2 1 1 3 3 3 1 Phage integrase, N-terminal SAM-like domain Arm-DNA-bind_4 PF14657.6 ABK72483.1 - 3.4e-05 23.5 0.5 3.4e-05 23.5 0.5 1.9 2 0 0 2 2 2 1 Arm DNA-binding domain Phage_int_SAM_4 PF13495.6 ABK72483.1 - 9.7e-05 22.8 0.0 0.001 19.5 0.0 2.2 1 1 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_3 PF14659.6 ABK72483.1 - 0.0032 17.7 0.0 0.0057 16.9 0.0 1.4 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain DUF2624 PF11116.8 ABK72483.1 - 0.079 13.9 0.1 0.45 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2624) Big_10 PF17964.1 ABK72483.1 - 0.086 12.8 0.0 0.46 10.4 0.0 2.0 2 0 0 2 2 2 0 Bacterial Ig domain DUF2222 PF09984.9 ABK72483.1 - 0.12 12.3 0.1 0.79 9.6 0.0 2.1 1 1 1 2 2 2 0 Uncharacterised signal transduction histidine kinase domain (DUF2222) PemK_toxin PF02452.17 ABK72484.1 - 3.6e-20 72.4 0.0 3.9e-20 72.3 0.0 1.0 1 0 0 1 1 1 1 PemK-like, MazF-like toxin of type II toxin-antitoxin system CcdB PF01845.17 ABK72484.1 - 0.00079 19.6 0.0 0.00094 19.4 0.0 1.1 1 0 0 1 1 1 1 CcdB protein LCM PF04072.14 ABK72485.1 - 5.2e-66 222.2 0.0 6.9e-66 221.8 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase LMBR1 PF04791.16 ABK72486.1 - 0.66 8.8 6.7 0.72 8.7 6.7 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Borrelia_P83 PF05262.11 ABK72486.1 - 2.1 6.7 27.4 2.2 6.7 27.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Presenilin PF01080.17 ABK72486.1 - 8.2 5.1 18.7 10 4.7 18.7 1.1 1 0 0 1 1 1 0 Presenilin DDHD PF02862.17 ABK72486.1 - 8.5 6.5 12.7 13 5.9 12.7 1.3 1 0 0 1 1 1 0 DDHD domain ADH_N PF08240.12 ABK72487.1 - 1.1e-28 99.3 1.3 2e-28 98.5 1.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ABK72487.1 - 2.3e-17 63.2 1.0 3.7e-17 62.5 1.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ABK72487.1 - 4.8e-07 30.9 1.3 5.4e-07 30.7 0.3 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ABK72487.1 - 4.2e-06 26.4 1.2 6.3e-06 25.8 1.2 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus 2-Hacid_dh_C PF02826.19 ABK72487.1 - 0.013 14.9 0.1 0.019 14.3 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_N_2 PF16884.5 ABK72487.1 - 0.031 14.2 0.0 0.073 13.0 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase NADH_4Fe-4S PF10589.9 ABK72487.1 - 0.33 11.0 2.0 0.83 9.8 2.0 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Ald_Xan_dh_C2 PF02738.18 ABK72488.1 - 4.1e-150 500.8 5.1 6e-150 500.3 5.1 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Fer2_2 PF01799.20 ABK72488.1 - 1.3e-25 89.2 1.0 3.5e-25 87.8 1.0 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.22 ABK72488.1 - 9.1e-25 87.2 0.4 2e-24 86.1 0.4 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2 PF00111.27 ABK72488.1 - 0.00011 22.1 0.5 0.00011 22.1 0.5 3.0 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 ABK72488.1 - 0.032 14.2 0.1 0.46 10.5 0.1 2.5 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain ECH_1 PF00378.20 ABK72489.1 - 7.5e-58 195.8 0.0 9.1e-58 195.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK72489.1 - 3.5e-17 62.9 0.0 4.8e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Chorismate_synt PF01264.21 ABK72490.1 - 1.6e-118 395.2 0.4 1.8e-118 395.0 0.4 1.0 1 0 0 1 1 1 1 Chorismate synthase DUF3417 PF11897.8 ABK72491.1 - 9.7e-36 122.5 0.0 1.9e-35 121.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3417) Phosphorylase PF00343.20 ABK72491.1 - 7.6e-26 90.6 0.0 6.5e-10 37.9 0.0 3.6 3 1 0 3 3 3 3 Carbohydrate phosphorylase DUF498 PF04430.14 ABK72492.1 - 0.18 11.9 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) Bac_luciferase PF00296.20 ABK72493.1 - 5.4e-61 206.7 0.9 7.3e-61 206.3 0.9 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase TENA_THI-4 PF03070.16 ABK72494.1 - 2.2e-61 207.3 0.0 2.5e-61 207.2 0.0 1.0 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Haem_oxygenas_2 PF14518.6 ABK72494.1 - 4e-08 33.2 0.1 6e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 Iron-containing redox enzyme Phosphonate-bd PF12974.7 ABK72495.1 - 1.1e-12 48.1 0.6 1.5e-12 47.7 0.6 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 ABK72495.1 - 1.7e-12 47.7 0.0 2.7e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_3 PF16868.5 ABK72495.1 - 6.6e-09 35.6 0.0 6e-06 25.9 0.0 2.4 3 0 0 3 3 3 2 NMT1-like family SBP_bac_3 PF00497.20 ABK72495.1 - 1.1e-08 34.8 0.0 2e-08 33.9 0.0 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_2 PF13379.6 ABK72495.1 - 1.2e-08 35.0 0.6 4.3e-08 33.2 0.6 1.9 1 1 0 1 1 1 1 NMT1-like family OpuAC PF04069.12 ABK72495.1 - 0.00085 19.0 0.4 0.034 13.7 0.1 2.1 1 1 1 2 2 2 2 Substrate binding domain of ABC-type glycine betaine transport system DEDD_Tnp_IS110 PF01548.17 ABK72496.1 - 1.6e-37 128.7 0.7 3.6e-37 127.6 0.2 1.8 2 0 0 2 2 2 1 Transposase Transposase_20 PF02371.16 ABK72496.1 - 1.3e-10 41.5 0.1 4.3e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 Transposase IS116/IS110/IS902 family DNA_ligase_aden PF01653.18 ABK72497.1 - 3e-124 414.3 0.0 4e-124 413.8 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 ABK72497.1 - 6.7e-31 106.0 1.5 1.3e-30 105.1 1.5 1.5 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain HHH_2 PF12826.7 ABK72497.1 - 2.9e-23 81.8 0.3 7.7e-23 80.4 0.1 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif BRCT PF00533.26 ABK72497.1 - 1.5e-11 44.5 0.0 2.4e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain HHH_5 PF14520.6 ABK72497.1 - 1.1e-09 38.7 0.4 1.6e-07 31.9 0.1 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_ligase_ZBD PF03119.16 ABK72497.1 - 3.8e-09 36.4 5.2 3.8e-09 36.4 5.2 2.0 2 0 0 2 2 2 1 NAD-dependent DNA ligase C4 zinc finger domain PTCB-BRCT PF12738.7 ABK72497.1 - 4.3e-07 29.8 0.0 1.1e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain HHH PF00633.23 ABK72497.1 - 1.7e-06 27.6 2.2 2.9e-06 26.9 0.3 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix motif Bactofilin PF04519.13 ABK72497.1 - 0.36 11.1 1.8 9.1 6.6 0.1 2.6 2 0 0 2 2 2 0 Polymer-forming cytoskeletal VWA_2 PF13519.6 ABK72498.1 - 1.3e-05 25.8 0.0 2.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 ABK72498.1 - 0.00045 20.5 0.0 0.00054 20.3 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF4131 PF13567.6 ABK72498.1 - 2.8 7.6 6.0 2.6 7.7 3.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) CPBP PF02517.16 ABK72500.1 - 8 6.9 8.4 0.49 10.8 1.9 2.2 2 1 0 2 2 2 0 CPBP intramembrane metalloprotease NMO PF03060.15 ABK72501.1 - 2.2e-54 185.1 0.5 3.2e-54 184.5 0.5 1.3 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 ABK72501.1 - 1.1e-11 44.3 3.9 1.9e-11 43.6 3.9 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 ABK72501.1 - 1e-05 24.7 0.0 0.0044 16.1 1.4 2.4 2 1 1 3 3 3 2 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 ABK72501.1 - 0.012 15.1 0.6 0.025 14.0 0.1 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein Glu_synthase PF01645.17 ABK72501.1 - 0.013 14.7 0.1 0.013 14.7 0.1 2.0 2 0 0 2 2 2 0 Conserved region in glutamate synthase ThiG PF05690.14 ABK72501.1 - 0.026 13.8 2.8 0.037 13.3 1.9 1.7 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG IF2_N PF04760.15 ABK72501.1 - 0.078 12.8 0.0 0.54 10.1 0.0 2.2 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region PK_C PF02887.16 ABK72501.1 - 0.15 12.3 0.2 3 8.1 0.0 2.9 3 1 1 4 4 4 0 Pyruvate kinase, alpha/beta domain DHO_dh PF01180.21 ABK72501.1 - 0.27 10.4 0.6 0.43 9.7 0.6 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Acetyltransf_8 PF13523.6 ABK72502.1 - 9.6e-44 148.6 0.1 1.2e-43 148.3 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ABK72502.1 - 0.001 19.7 0.0 0.0015 19.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ABK72502.1 - 0.029 14.6 0.0 0.043 14.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Methyltransf_4 PF02390.17 ABK72503.1 - 5.9e-54 182.1 0.0 7.4e-54 181.8 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_3 PF01596.17 ABK72503.1 - 2.8e-05 23.4 0.0 3.5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_25 PF13649.6 ABK72503.1 - 6.3e-05 23.6 0.0 9.7e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABK72503.1 - 0.00086 19.1 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ABK72503.1 - 0.0012 18.6 0.0 0.002 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 ABK72503.1 - 0.013 15.0 0.0 0.03 13.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Methyltr_RsmB-F PF01189.17 ABK72503.1 - 0.016 14.9 0.0 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F DUF938 PF06080.12 ABK72503.1 - 0.022 14.5 0.0 0.032 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_18 PF12847.7 ABK72503.1 - 0.024 14.6 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 ABK72503.1 - 0.028 14.3 0.0 0.18 11.7 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 ABK72503.1 - 0.051 14.2 0.0 0.084 13.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 ABK72503.1 - 0.054 12.8 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_24 PF13578.6 ABK72503.1 - 0.058 14.4 0.0 0.11 13.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 ABK72503.1 - 0.068 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_12 PF08242.12 ABK72503.1 - 0.089 13.5 0.0 0.16 12.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain FA_desaturase PF00487.24 ABK72504.1 - 7.9e-33 114.4 11.7 7.9e-33 114.4 11.7 2.3 2 0 0 2 2 2 1 Fatty acid desaturase Exonuc_VII_S PF02609.16 ABK72505.1 - 6.6e-19 67.7 0.6 7.9e-19 67.5 0.6 1.1 1 0 0 1 1 1 1 Exonuclease VII small subunit 2-Hacid_dh_C PF02826.19 ABK72506.1 - 1.3e-39 135.4 0.0 2.8e-39 134.3 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ABK72506.1 - 1.1e-06 28.4 0.0 1.3e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 ABK72506.1 - 0.035 14.7 0.0 0.094 13.3 0.0 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Mce4_CUP1 PF11887.8 ABK72507.1 - 7.8e-52 176.3 0.0 9.8e-52 175.9 0.0 1.1 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative MlaD PF02470.20 ABK72507.1 - 2.3e-13 50.3 0.0 4.7e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 MlaD protein DUF2275 PF10039.9 ABK72507.1 - 0.022 14.9 0.2 0.037 14.1 0.2 1.3 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) DUF1110 PF06533.12 ABK72507.1 - 0.037 14.0 0.4 0.066 13.2 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1110) BPD_transp_1 PF00528.22 ABK72508.1 - 7e-18 65.0 23.9 9.3e-18 64.6 23.9 1.2 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component HATPase_c PF02518.26 ABK72510.1 - 6.9e-10 39.4 0.0 1.4e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 ABK72510.1 - 7.9e-08 32.6 0.1 2.8e-07 30.8 0.1 2.0 1 0 0 1 1 1 1 HAMP domain HATPase_c_3 PF13589.6 ABK72510.1 - 0.038 13.8 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glycos_transf_2 PF00535.26 ABK72511.1 - 7.6e-30 103.9 0.0 9.6e-30 103.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ABK72511.1 - 8.9e-09 35.6 0.0 1.1e-08 35.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 BTAD PF03704.17 ABK72512.1 - 2.7e-32 112.2 12.5 2.7e-32 112.2 12.5 4.9 4 2 1 5 5 5 1 Bacterial transcriptional activator domain AAA_16 PF13191.6 ABK72512.1 - 7e-20 72.1 4.1 1.5e-19 71.0 0.0 3.5 3 0 0 3 3 3 1 AAA ATPase domain Trans_reg_C PF00486.28 ABK72512.1 - 1.7e-12 47.2 0.0 4.4e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal AAA_22 PF13401.6 ABK72512.1 - 5e-09 36.6 0.0 1.5e-08 35.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 ABK72512.1 - 0.00012 22.5 0.0 0.00026 21.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 ABK72512.1 - 0.00061 19.0 0.0 0.0011 18.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_5 PF07728.14 ABK72512.1 - 0.01 15.8 0.0 0.067 13.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 ABK72512.1 - 0.012 15.6 0.0 0.031 14.2 0.0 1.7 1 1 0 1 1 1 0 NACHT domain RuvB_N PF05496.12 ABK72512.1 - 0.036 13.8 0.0 0.1 12.3 0.0 1.8 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 ABK72512.1 - 0.057 13.6 0.1 0.45 10.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain TP_methylase PF00590.20 ABK72513.1 - 4.7e-80 268.5 12.7 3.5e-48 164.4 3.6 2.0 2 0 0 2 2 2 2 Tetrapyrrole (Corrin/Porphyrin) Methylases adh_short PF00106.25 ABK72514.1 - 1.3e-44 152.0 0.0 1.6e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK72514.1 - 4e-34 118.2 0.1 5.2e-34 117.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK72514.1 - 2e-14 53.9 0.0 3e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ABK72514.1 - 1.2e-05 25.3 0.4 1.6e-05 24.9 0.4 1.4 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 ABK72514.1 - 0.0001 21.5 0.0 0.00013 21.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 ABK72514.1 - 0.018 14.5 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 ABK72514.1 - 0.031 14.9 0.1 0.066 13.8 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Glyoxalase PF00903.25 ABK72515.1 - 5e-22 78.5 0.0 7.1e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ABK72515.1 - 4.4e-06 26.9 0.0 1.7e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily LEM PF03020.15 ABK72515.1 - 0.22 11.1 0.0 0.39 10.3 0.0 1.4 1 0 0 1 1 1 0 LEM domain CoA_transf_3 PF02515.17 ABK72516.1 - 4.9e-114 381.3 0.9 5.5e-114 381.1 0.9 1.0 1 0 0 1 1 1 1 CoA-transferase family III Bac_luciferase PF00296.20 ABK72517.1 - 2.4e-72 244.0 5.1 3e-72 243.7 5.1 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase SBP_bac_5 PF00496.22 ABK72518.1 - 1.7e-66 224.7 8.4 2.4e-66 224.2 8.4 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Integrase_H2C2 PF17921.1 ABK72518.1 - 0.039 14.0 0.1 0.09 12.9 0.0 1.6 2 0 0 2 2 2 0 Integrase zinc binding domain DUF664 PF04978.12 ABK72519.1 - 1.4e-30 106.7 0.0 5.9e-30 104.7 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF664) DinB_2 PF12867.7 ABK72519.1 - 1.8e-13 51.1 0.7 3.7e-13 50.1 0.4 1.6 1 1 1 2 2 2 2 DinB superfamily ArAE_2_N PF10337.9 ABK72519.1 - 0.083 11.9 0.0 1.5 7.8 0.0 2.0 2 0 0 2 2 2 0 Putative ER transporter, 6TM, N-terminal Allexi_40kDa PF05549.11 ABK72519.1 - 0.088 12.3 0.0 0.23 10.9 0.0 1.6 2 0 0 2 2 2 0 Allexivirus 40kDa protein DotD PF16816.5 ABK72519.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 DotD protein MFS_1 PF07690.16 ABK72520.1 - 3.7e-69 233.3 38.7 2.7e-58 197.6 20.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ABK72520.1 - 6.3e-07 29.0 23.6 1.1e-05 25.0 2.3 2.9 2 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 ABK72520.1 - 6.2e-06 24.9 2.0 6.2e-06 24.9 2.0 2.1 2 0 0 2 2 2 1 Transmembrane secretion effector ATG22 PF11700.8 ABK72520.1 - 8.8e-06 24.6 7.1 8.8e-06 24.6 7.1 2.2 2 1 0 2 2 2 1 Vacuole effluxer Atg22 like LacY_symp PF01306.19 ABK72520.1 - 0.023 13.5 15.4 0.26 10.0 0.8 2.2 2 0 0 2 2 2 0 LacY proton/sugar symporter DUF4538 PF15061.6 ABK72520.1 - 2 8.2 6.2 12 5.8 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4538) DUF4131 PF13567.6 ABK72520.1 - 6.4 6.4 13.2 3.5 7.2 0.1 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) Fer2_2 PF01799.20 ABK72521.1 - 9.1e-30 102.5 0.4 9.1e-30 102.5 0.4 1.6 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fer2 PF00111.27 ABK72521.1 - 2.7e-08 33.6 1.0 2.7e-08 33.6 1.0 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 ABK72521.1 - 2.4e-05 24.3 0.7 6.1e-05 23.0 0.6 1.8 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain TAT_signal PF10518.9 ABK72521.1 - 0.19 11.6 0.1 0.19 11.6 0.1 2.3 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence zf-UBR PF02207.20 ABK72521.1 - 5.2 7.3 8.1 0.18 12.0 0.5 2.3 3 0 0 3 3 3 0 Putative zinc finger in N-recognin (UBR box) Epimerase PF01370.21 ABK72522.1 - 1.1e-45 156.1 0.1 9.3e-45 153.0 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ABK72522.1 - 6e-43 147.5 0.0 3.3e-23 82.6 0.0 2.8 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 ABK72522.1 - 1.4e-15 57.2 0.1 1.2e-07 31.2 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain 3Beta_HSD PF01073.19 ABK72522.1 - 4.2e-15 55.5 0.0 4.6e-10 39.0 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 ABK72522.1 - 7.9e-13 48.2 0.0 1.6e-05 24.2 0.0 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 ABK72522.1 - 9.5e-12 44.6 0.0 1e-08 34.7 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.25 ABK72522.1 - 2.9e-07 30.1 0.0 3.2e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.6 ABK72522.1 - 0.0036 17.2 0.1 0.0065 16.4 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding adh_short_C2 PF13561.6 ABK72522.1 - 0.005 16.4 0.0 0.017 14.7 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK72522.1 - 0.0052 16.7 1.3 0.015 15.2 1.3 1.8 1 1 0 1 1 1 1 KR domain NAD_binding_8 PF13450.6 ABK72522.1 - 0.0092 16.2 0.1 0.053 13.7 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 ABK72522.1 - 0.065 13.1 0.1 0.25 11.2 0.1 1.8 1 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 ABK72522.1 - 0.14 12.2 0.1 0.48 10.5 0.1 1.9 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 ABK72522.1 - 0.16 12.1 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Methyltransf_25 PF13649.6 ABK72522.1 - 0.17 12.6 0.2 27 5.6 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain BPD_transp_1 PF00528.22 ABK72523.1 - 1.3e-13 51.1 12.7 1.3e-13 51.1 12.7 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 ABK72524.1 - 4.2e-27 95.1 13.6 7.4e-27 94.3 13.6 1.4 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 ABK72524.1 - 0.053 13.5 0.1 0.053 13.5 0.1 2.8 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Phage_holin_5_1 PF06946.11 ABK72524.1 - 5.9 7.3 8.8 3.4 8.1 1.7 3.3 2 1 0 3 3 3 0 Bacteriophage A118-like holin, Hol118 SIR2 PF02146.17 ABK72526.1 - 1e-51 175.4 0.0 1.2e-51 175.1 0.0 1.0 1 0 0 1 1 1 1 Sir2 family Zn-ribbon_8 PF09723.10 ABK72526.1 - 0.0025 17.9 0.4 0.0043 17.1 0.4 1.3 1 0 0 1 1 1 1 Zinc ribbon domain PNTB PF02233.16 ABK72526.1 - 0.0041 16.1 0.3 0.0058 15.6 0.3 1.1 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit CpXC PF14353.6 ABK72526.1 - 0.15 12.1 0.1 0.56 10.3 0.1 1.8 1 1 1 2 2 2 0 CpXC protein TPP_enzyme_M PF00205.22 ABK72526.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain adh_short_C2 PF13561.6 ABK72527.1 - 2e-59 201.0 1.8 2.5e-59 200.7 1.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK72527.1 - 1e-51 175.2 0.2 1.3e-51 174.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK72527.1 - 1.3e-10 41.5 0.2 1.7e-10 41.1 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK72527.1 - 4.1e-05 23.2 0.8 0.00053 19.5 0.8 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 ABK72527.1 - 0.0076 16.5 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ADH_zinc_N PF00107.26 ABK72527.1 - 0.0078 16.2 1.3 0.016 15.2 1.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 3HCDH_N PF02737.18 ABK72527.1 - 0.18 11.7 0.5 0.93 9.3 0.3 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ribonuc_red_sm PF00268.21 ABK72528.1 - 4.9e-18 65.6 0.0 6.3e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Rubrerythrin PF02915.17 ABK72528.1 - 0.11 12.9 0.1 8.8 6.7 0.0 2.7 2 1 1 3 3 3 0 Rubrerythrin DUF58 PF01882.18 ABK72529.1 - 2.6e-19 69.3 0.0 5.5e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF58 VWA_2 PF13519.6 ABK72529.1 - 0.00015 22.3 0.0 0.00029 21.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain MFS_1 PF07690.16 ABK72530.1 - 7.7e-37 127.0 56.1 7.7e-37 127.0 56.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF5313 PF17240.2 ABK72530.1 - 0.12 12.8 1.1 0.43 11.0 1.1 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5313) DnaJ_C PF01556.18 ABK72531.1 - 1.7e-38 132.0 0.0 3.3e-38 131.1 0.0 1.4 1 1 1 2 2 2 1 DnaJ C terminal domain DnaJ PF00226.31 ABK72531.1 - 8.5e-25 86.7 0.4 1.3e-24 86.1 0.4 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 ABK72531.1 - 7.9e-13 48.6 15.0 1.3e-12 47.9 15.0 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 ABK72531.1 - 4.4e-06 26.6 14.9 0.00066 19.6 4.4 2.6 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein DUF5351 PF17302.2 ABK72531.1 - 6.2 7.1 20.4 2.5 8.4 6.0 4.2 3 1 0 3 3 3 0 Family of unknown function (DUF5351) ABC_tran PF00005.27 ABK72533.1 - 7.2e-28 97.8 0.0 1.3e-27 97.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK72533.1 - 9.3e-10 38.8 0.4 6.5e-06 26.2 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 ABK72533.1 - 0.0024 17.5 0.1 0.029 14.0 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ABK72533.1 - 0.0025 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ABK72533.1 - 0.0061 16.5 0.1 0.013 15.4 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 ABK72533.1 - 0.012 15.0 0.1 0.15 11.5 0.1 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA PF00004.29 ABK72533.1 - 0.015 15.7 0.0 0.1 13.0 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ABK72533.1 - 0.028 14.8 0.1 0.088 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain PPV_E1_C PF00519.17 ABK72533.1 - 0.035 12.9 0.1 0.075 11.9 0.0 1.5 2 0 0 2 2 2 0 Papillomavirus helicase NACHT PF05729.12 ABK72533.1 - 0.044 13.7 0.2 0.34 10.8 0.1 2.2 1 1 1 2 2 2 0 NACHT domain AAA_22 PF13401.6 ABK72533.1 - 0.048 13.9 0.5 0.37 11.1 0.5 2.5 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ABK72533.1 - 0.086 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 ABK72533.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 ABK72533.1 - 0.15 11.7 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF3729 PF12526.8 ABK72533.1 - 0.24 13.0 0.1 0.24 13.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3729) AAA_15 PF13175.6 ABK72533.1 - 0.25 11.0 0.1 5.1 6.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain PfkB PF00294.24 ABK72535.1 - 7.9e-35 120.6 4.2 9.7e-35 120.3 4.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Tic110 PF16940.5 ABK72535.1 - 1.2 7.5 5.7 1.9 6.8 5.7 1.3 1 0 0 1 1 1 0 Chloroplast envelope transporter Acyl-CoA_dh_N PF02771.16 ABK72537.1 - 4e-22 79.0 0.1 7.2e-22 78.2 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 ABK72537.1 - 2.1e-18 67.0 0.0 3.3e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK72537.1 - 3.8e-16 59.1 0.0 1.1e-15 57.6 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain NifU PF01106.17 ABK72538.1 - 2e-21 75.9 0.2 2e-21 75.9 0.2 2.3 3 0 0 3 3 3 1 NifU-like domain Rieske PF00355.26 ABK72538.1 - 3.7e-11 42.8 0.0 7.5e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 ABK72538.1 - 2.2e-05 24.4 0.0 4.4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain MukE PF04288.13 ABK72538.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 MukE-like family Transketolase_N PF00456.21 ABK72539.1 - 7.8e-30 104.0 0.3 1.5e-29 103.0 0.3 1.4 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.6 ABK72539.1 - 1.1e-13 51.0 0.0 2.6e-11 43.3 0.0 2.6 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 ABK72539.1 - 4.6e-06 25.8 0.0 6.3e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component XFP_N PF09364.10 ABK72539.1 - 1.8e-05 23.7 0.0 2.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 XFP N-terminal domain TPP_enzyme_C PF02775.21 ABK72539.1 - 4.1e-05 23.4 1.1 0.0018 18.0 0.6 2.9 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain EPSP_synthase PF00275.20 ABK72540.1 - 2.3e-111 372.5 0.0 2.6e-111 372.3 0.0 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DUF2397 PF09660.10 ABK72540.1 - 0.02 13.8 0.3 1.4 7.7 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2397) Phage_GPD PF05954.11 ABK72540.1 - 0.026 13.8 0.1 0.087 12.1 0.0 1.7 2 0 0 2 2 2 0 Phage late control gene D protein (GPD) MFS_1 PF07690.16 ABK72541.1 - 1.5e-22 80.0 37.3 1.5e-22 80.0 37.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily ATG22 PF11700.8 ABK72541.1 - 5.5e-22 78.0 13.4 5.5e-22 78.0 13.4 2.4 2 1 0 2 2 2 1 Vacuole effluxer Atg22 like Cyclophil_like PF04126.13 ABK72541.1 - 0.0015 18.3 0.0 0.0028 17.5 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin-like OATP PF03137.20 ABK72541.1 - 0.99 7.6 5.8 1.4 7.2 4.1 1.9 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF1129 PF06570.11 ABK72541.1 - 5 6.5 6.0 0.6 9.6 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) Aldedh PF00171.22 ABK72542.1 - 6.2e-135 450.3 1.0 7.8e-135 450.0 1.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ABC_tran PF00005.27 ABK72543.1 - 9e-56 188.2 0.0 7.2e-28 97.8 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ABK72543.1 - 3.4e-11 43.5 10.3 2.7e-05 24.2 0.1 4.3 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK72543.1 - 3.7e-11 42.9 0.7 1.7e-05 24.4 0.0 3.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain oligo_HPY PF08352.12 ABK72543.1 - 8.4e-09 35.8 0.0 0.00066 20.1 0.0 2.5 2 0 0 2 2 2 2 Oligopeptide/dipeptide transporter, C-terminal region AAA_22 PF13401.6 ABK72543.1 - 3.2e-07 30.7 7.8 0.0027 18.0 0.7 4.1 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 ABK72543.1 - 1.3e-06 28.1 2.0 0.026 14.2 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 ABK72543.1 - 1.5e-06 28.7 3.9 0.02 15.3 0.3 2.6 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 ABK72543.1 - 0.00043 20.2 0.6 0.49 10.3 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase NB-ARC PF00931.22 ABK72543.1 - 0.0046 16.2 0.2 1.7 7.8 0.1 2.2 2 0 0 2 2 2 2 NB-ARC domain APS_kinase PF01583.20 ABK72543.1 - 0.0093 15.9 0.3 0.48 10.3 0.1 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase IstB_IS21 PF01695.17 ABK72543.1 - 0.013 15.2 1.6 1.7 8.3 0.0 3.2 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_23 PF13476.6 ABK72543.1 - 0.041 14.4 0.0 8.1 6.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain FAD-oxidase_C PF02913.19 ABK72543.1 - 0.052 13.2 0.2 0.095 12.3 0.2 1.3 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain AAA_24 PF13479.6 ABK72543.1 - 0.059 13.1 0.6 12 5.6 0.0 2.9 3 1 0 3 3 3 0 AAA domain AAA PF00004.29 ABK72543.1 - 0.061 13.7 0.0 15 6.0 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 ABK72543.1 - 0.066 12.7 0.1 7 6.1 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 ABK72543.1 - 0.079 12.7 0.2 12 5.5 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain ATP-synt_ab PF00006.25 ABK72543.1 - 0.11 12.2 0.2 9.2 5.9 0.1 2.4 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.6 ABK72543.1 - 0.11 12.7 1.9 3.6 7.9 0.3 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 ABK72543.1 - 0.18 11.9 6.4 0.63 10.1 0.4 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_18 PF13238.6 ABK72543.1 - 0.29 11.7 0.8 3.2 8.3 0.2 2.9 2 1 0 2 2 2 0 AAA domain PRK PF00485.18 ABK72543.1 - 0.52 10.0 1.7 3.6 7.3 0.3 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 ABK72543.1 - 1.9 8.6 4.8 5.4 7.2 0.5 2.8 2 2 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ABK72543.1 - 2.5 7.6 10.9 8.8 5.9 1.2 3.8 3 1 0 3 3 3 0 AAA domain AAA_30 PF13604.6 ABK72543.1 - 3.4 7.3 13.6 1.6 8.4 1.0 3.5 5 1 0 5 5 3 0 AAA domain SHOCT PF09851.9 ABK72544.1 - 6.9e-08 32.0 2.8 1e-07 31.4 2.8 1.3 1 0 0 1 1 1 1 Short C-terminal domain FAD_oxidored PF12831.7 ABK72545.1 - 4.9e-79 266.7 0.8 2e-57 195.5 0.0 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase DAO PF01266.24 ABK72545.1 - 5.2e-08 32.8 0.5 2.8e-07 30.4 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ABK72545.1 - 8.1e-08 31.8 9.9 1.5e-07 30.9 6.9 2.7 2 2 2 4 4 4 1 FAD binding domain Pyr_redox_2 PF07992.14 ABK72545.1 - 8.3e-08 31.8 0.4 1.4e-07 31.0 0.4 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ABK72545.1 - 6.7e-07 28.8 1.2 6.7e-07 28.8 1.2 2.1 3 0 0 3 3 3 1 Thi4 family NAD_binding_8 PF13450.6 ABK72545.1 - 2e-06 27.9 1.7 4.9e-06 26.7 1.7 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 ABK72545.1 - 2.1e-06 27.1 4.0 3.9e-06 26.2 3.3 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 ABK72545.1 - 4.2e-06 26.3 2.4 7.5e-06 25.4 2.4 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 ABK72545.1 - 1.6e-05 25.3 0.7 0.00014 22.3 1.4 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ABK72545.1 - 3.3e-05 22.8 2.9 5e-05 22.2 2.9 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 ABK72545.1 - 0.00049 19.4 0.2 0.0009 18.6 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ABK72545.1 - 0.0054 16.0 2.8 0.011 15.1 2.8 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 ABK72545.1 - 0.0056 15.6 0.9 0.028 13.3 1.7 1.7 2 0 0 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.12 ABK72545.1 - 0.0059 15.7 1.2 0.01 14.9 1.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 ABK72545.1 - 0.096 12.7 1.1 0.2 11.7 1.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 ABK72545.1 - 0.2 11.5 1.3 0.36 10.7 1.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain LysR_substrate PF03466.20 ABK72546.1 - 3.9e-37 127.6 4.3 5.9e-37 127.1 4.3 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 ABK72546.1 - 1.5e-15 56.9 0.9 3.1e-15 55.9 0.9 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 ABK72546.1 - 0.0079 16.1 2.8 0.019 14.9 0.2 2.7 3 0 0 3 3 3 1 MarR family 5-FTHF_cyc-lig PF01812.20 ABK72547.1 - 4.2e-39 134.3 0.0 4.7e-39 134.2 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family UPF0047 PF01894.17 ABK72548.1 - 1.9e-25 89.2 0.0 2.5e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Dioxygenase_C PF00775.21 ABK72549.1 - 1.2e-16 60.7 0.0 1.4e-14 53.9 0.0 2.1 1 1 0 1 1 1 1 Dioxygenase CarboxypepD_reg PF13620.6 ABK72549.1 - 0.00025 21.3 1.2 0.003 17.8 1.2 2.3 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain Flg_new PF09479.10 ABK72549.1 - 0.028 14.6 0.3 0.079 13.1 0.6 1.6 2 0 0 2 2 2 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) Lipase_C PF18067.1 ABK72549.1 - 0.094 13.3 0.0 0.15 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipase C-terminal domain PNP_UDP_1 PF01048.20 ABK72550.1 - 1.3e-43 148.9 4.1 1.5e-43 148.7 4.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Abhydrolase_1 PF00561.20 ABK72551.1 - 4e-20 72.5 0.0 3.6e-16 59.6 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ABK72551.1 - 4e-15 55.7 0.1 4.2e-11 42.6 0.2 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Ndr PF03096.14 ABK72551.1 - 0.0008 18.2 0.0 0.0012 17.6 0.0 1.2 1 0 0 1 1 1 1 Ndr family Peptidase_S28 PF05577.12 ABK72551.1 - 0.0023 16.8 0.0 0.0032 16.3 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_4 PF08386.10 ABK72551.1 - 0.03 14.5 0.0 0.065 13.4 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein LIDHydrolase PF10230.9 ABK72551.1 - 0.22 11.1 0.0 0.32 10.5 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase MlaD PF02470.20 ABK72552.1 - 2e-15 56.8 0.1 4.7e-15 55.7 0.1 1.7 1 0 0 1 1 1 1 MlaD protein Mce4_CUP1 PF11887.8 ABK72552.1 - 3.5e-06 26.7 0.6 5.7e-06 26.0 0.6 1.3 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative DUF4131 PF13567.6 ABK72552.1 - 0.032 13.9 0.7 2.9 7.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Baculo_PEP_C PF04513.12 ABK72552.1 - 0.041 13.9 3.0 1.5 8.9 1.6 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF296 PF03479.15 ABK72552.1 - 0.13 12.7 0.1 15 6.1 0.0 2.5 2 0 0 2 2 2 0 Plants and Prokaryotes Conserved (PCC) domain Ribophorin_II PF05817.14 ABK72552.1 - 0.13 10.8 0.3 0.19 10.2 0.3 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II Mating_N PF12731.7 ABK72552.1 - 0.19 11.8 1.1 0.51 10.5 0.2 2.2 2 1 1 3 3 3 0 Mating-type protein beta 1 TauD PF02668.16 ABK72553.1 - 2e-62 211.4 1.6 2.4e-62 211.1 1.6 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DNA_pol_viral_N PF00242.17 ABK72554.1 - 0.0086 15.6 0.2 0.013 15.1 0.2 1.1 1 0 0 1 1 1 1 DNA polymerase (viral) N-terminal domain DUF4391 PF14335.6 ABK72554.1 - 0.25 11.0 1.3 0.54 9.9 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) AMP-binding PF00501.28 ABK72555.1 - 1e-108 363.7 0.0 1.2e-108 363.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK72555.1 - 3.2e-20 72.9 1.0 8.9e-20 71.5 0.4 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Acetyltransf_1 PF00583.25 ABK72556.1 - 2.4e-11 43.9 0.1 3.1e-11 43.5 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ABK72556.1 - 4.4e-09 36.6 0.0 7.2e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ABK72556.1 - 8.5e-09 35.4 0.0 1.1e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ABK72556.1 - 3.6e-05 23.7 0.0 6.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_6 PF13480.7 ABK72556.1 - 0.0019 18.4 2.3 0.0028 17.8 2.3 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ABK72556.1 - 0.0037 17.4 0.0 0.0079 16.3 0.0 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase UCR_14kD PF02271.16 ABK72556.1 - 0.011 15.7 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit MTES_1575 PF18741.1 ABK72557.1 - 2.9e-05 24.2 0.1 6e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 REase_MTES_1575 AbiEi_1 PF09407.10 ABK72557.1 - 0.006 16.9 0.1 0.012 15.9 0.0 1.7 2 0 0 2 2 2 1 AbiEi antitoxin C-terminal domain DUF3817 PF12823.7 ABK72558.1 - 2.8e-25 88.9 6.3 3.2e-25 88.7 6.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3817) BPD_transp_2 PF02653.16 ABK72559.1 - 1.2e-37 129.6 53.9 7.2e-37 127.0 53.9 2.4 1 1 0 1 1 1 1 Branched-chain amino acid transport system / permease component DUF3767 PF12597.8 ABK72559.1 - 1.2 9.0 4.4 4.3 7.2 0.2 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3767) ArfA PF03889.13 ABK72560.1 - 0.31 10.5 0.8 0.82 9.2 0.1 2.0 3 0 0 3 3 3 0 Alternative ribosome-rescue factor A adh_short_C2 PF13561.6 ABK72561.1 - 2.6e-24 86.1 2.8 3.9e-24 85.5 2.8 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK72561.1 - 2.8e-22 79.2 1.8 6.9e-21 74.6 0.2 2.1 1 1 1 2 2 2 2 short chain dehydrogenase RmlD_sub_bind PF04321.17 ABK72561.1 - 0.002 17.3 0.2 0.0031 16.7 0.2 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain SfLAP PF11139.8 ABK72563.1 - 0.0042 16.6 6.0 0.0042 16.6 6.0 2.0 1 1 1 2 2 2 1 Sap, sulfolipid-1-addressing protein MotA_ExbB PF01618.16 ABK72563.1 - 0.034 13.9 2.4 0.039 13.7 2.0 1.3 1 1 0 1 1 1 0 MotA/TolQ/ExbB proton channel family Cyt_bd_oxida_II PF02322.15 ABK72563.1 - 0.064 12.6 10.8 0.072 12.5 10.8 1.0 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II DUF3487 PF11990.8 ABK72563.1 - 0.14 12.1 8.1 0.033 14.1 4.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3487) DUF805 PF05656.14 ABK72563.1 - 0.17 12.3 7.6 0.21 12.0 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF805) DUF2953 PF11167.8 ABK72563.1 - 0.24 11.5 2.3 0.26 11.4 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2953) YfhO PF09586.10 ABK72563.1 - 0.38 8.9 1.6 0.44 8.7 1.6 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO OATP PF03137.20 ABK72563.1 - 0.53 8.5 3.0 0.38 9.0 2.0 1.2 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SLATT_fungal PF18142.1 ABK72563.1 - 0.72 9.9 3.3 0.77 9.8 3.3 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain DUF2244 PF10003.9 ABK72563.1 - 3.4 7.3 14.5 2.8 7.6 7.9 2.1 1 1 1 2 2 2 0 Integral membrane protein (DUF2244) VPDSG-CTERM PF18205.1 ABK72563.1 - 5.5 6.9 9.3 0.33 10.8 2.7 2.5 2 1 0 2 2 2 0 VPDSG-CTERM motif ATP-synt_S1 PF05827.12 ABK72563.1 - 6.3 6.6 5.3 9.6 6.0 2.0 2.2 1 1 1 2 2 2 0 Vacuolar ATP synthase subunit S1 (ATP6S1) DUF4191 PF13829.6 ABK72563.1 - 8.3 5.7 8.4 4.7 6.5 6.6 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4191) DAPG_hydrolase PF18089.1 ABK72564.1 - 4.2e-37 127.9 0.0 4.8e-37 127.7 0.0 1.0 1 0 0 1 1 1 1 DAPG hydrolase PhiG domain AP_endonuc_2 PF01261.24 ABK72565.1 - 2.6e-17 63.0 0.3 1.1e-16 61.0 0.3 1.9 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel MDMPI_N PF11716.8 ABK72566.1 - 4.3e-06 27.5 10.9 1.2e-05 26.0 10.9 2.1 1 1 0 1 1 1 1 Mycothiol maleylpyruvate isomerase N-terminal domain MDMPI_C PF07398.11 ABK72566.1 - 0.06 14.2 0.7 0.06 14.2 0.7 2.5 2 1 0 2 2 2 0 MDMPI C-terminal domain p450 PF00067.22 ABK72567.1 - 3.9e-32 111.6 0.0 7.9e-20 71.0 0.0 2.5 2 1 1 3 3 3 2 Cytochrome P450 BPD_transp_1 PF00528.22 ABK72568.1 - 1.1e-20 74.1 16.6 1.4e-20 73.8 16.6 1.2 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component SBP_bac_5 PF00496.22 ABK72569.1 - 2.5e-67 227.5 0.1 3.4e-67 227.1 0.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle LPAM_1 PF08139.12 ABK72569.1 - 0.039 14.5 0.6 0.09 13.3 0.6 1.7 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Acyl-CoA_dh_1 PF00441.24 ABK72571.1 - 4.4e-10 39.9 13.8 5e-10 39.8 7.5 2.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK72571.1 - 3.6e-06 27.6 0.1 9.5e-06 26.3 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ABK72571.1 - 0.00036 20.8 18.8 0.0008 19.7 10.2 3.6 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain SseC PF04888.12 ABK72571.1 - 0.43 10.1 8.6 0.77 9.3 8.6 1.4 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DIOX_N PF14226.6 ABK72572.1 - 6.4e-25 88.2 0.0 9.1e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ABK72572.1 - 1.6e-15 57.4 0.0 3.6e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ACC_epsilon PF13822.6 ABK72573.1 - 0.034 14.8 5.3 0.04 14.6 5.3 1.1 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit Transposase_mut PF00872.18 ABK72574.1 - 4.1e-64 216.8 0.0 5e-64 216.5 0.0 1.1 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 ABK72574.1 - 2.8e-07 30.8 0.0 6.2e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Ribosomal_S24e PF01282.19 ABK72574.1 - 0.042 13.8 0.1 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein S24e Leuk-A4-hydro_C PF09127.11 ABK72574.1 - 0.068 13.3 0.1 5.2 7.2 0.0 2.5 2 0 0 2 2 2 0 Leukotriene A4 hydrolase, C-terminal DNA_primase_S PF01896.19 ABK72575.1 - 0.021 14.9 0.0 0.2 11.7 0.0 2.3 1 1 0 1 1 1 0 DNA primase small subunit PNTB PF02233.16 ABK72576.1 - 4.8e-171 569.7 30.2 5.5e-171 569.5 30.2 1.0 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit Patatin PF01734.22 ABK72577.1 - 9.9e-16 58.5 5.4 2.4e-15 57.3 3.9 2.3 2 1 0 2 2 2 1 Patatin-like phospholipase NmrA PF05368.13 ABK72579.1 - 5.5e-20 71.9 0.0 6.9e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ABK72579.1 - 1.7e-07 31.3 0.1 3e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 ABK72579.1 - 1.4e-06 28.6 0.1 3.3e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 ABK72579.1 - 5.4e-05 23.3 0.0 0.00014 21.9 0.0 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Glu_dehyd_C PF16912.5 ABK72579.1 - 0.00012 21.6 0.2 0.0082 15.6 0.0 2.2 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus KR PF08659.10 ABK72579.1 - 0.028 14.4 0.5 0.044 13.7 0.1 1.5 2 0 0 2 2 2 0 KR domain F420_oxidored PF03807.17 ABK72579.1 - 0.052 14.1 0.1 0.13 12.9 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 ABK72579.1 - 0.061 13.8 0.4 0.33 11.4 0.1 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding K_oxygenase PF13434.6 ABK72579.1 - 0.096 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) GFO_IDH_MocA PF01408.22 ABK72579.1 - 0.12 13.2 0.0 0.27 12.1 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DUF3375 PF11855.8 ABK72581.1 - 3e-105 352.9 12.4 3.4e-105 352.7 12.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3375) SelA PF03841.13 ABK72582.1 - 1.1e-102 343.8 0.0 1.8e-102 343.1 0.0 1.3 1 0 0 1 1 1 1 L-seryl-tRNA selenium transferase Se-cys_synth_N PF12390.8 ABK72582.1 - 5.2e-07 29.8 6.0 5.2e-07 29.8 6.0 4.0 4 0 0 4 4 4 1 Selenocysteine synthase N terminal HTH_31 PF13560.6 ABK72582.1 - 0.014 15.8 14.4 0.78 10.1 1.1 5.0 4 1 1 5 5 5 0 Helix-turn-helix domain Aminotran_5 PF00266.19 ABK72582.1 - 0.13 11.2 0.0 0.3 10.0 0.0 1.5 1 1 0 1 1 1 0 Aminotransferase class-V HTH_38 PF13936.6 ABK72583.1 - 1.4e-19 69.6 3.5 1.6e-18 66.2 2.5 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain rve PF00665.26 ABK72583.1 - 9.7e-08 32.2 0.0 4.1e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain HTH_23 PF13384.6 ABK72583.1 - 1.5e-06 27.8 8.6 3.8e-05 23.3 1.7 4.4 4 0 0 4 4 4 1 Homeodomain-like domain HTH_32 PF13565.6 ABK72583.1 - 0.00033 21.2 13.5 0.00077 20.0 4.8 4.1 2 1 1 3 3 3 1 Homeodomain-like domain rve_3 PF13683.6 ABK72583.1 - 0.0016 18.2 0.0 0.0051 16.6 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain HTH_28 PF13518.6 ABK72583.1 - 0.002 18.2 1.9 0.014 15.5 1.9 2.6 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 ABK72583.1 - 0.0024 17.5 0.3 0.11 12.2 0.1 3.0 3 0 0 3 3 3 1 Sigma-70, region 4 GerE PF00196.19 ABK72583.1 - 0.023 14.2 0.4 0.1 12.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family HTH_20 PF12840.7 ABK72583.1 - 0.053 13.6 0.5 2.5 8.2 0.0 3.5 4 0 0 4 4 4 0 Helix-turn-helix domain DUF4097 PF13349.6 ABK72584.1 - 0.00033 20.1 0.0 0.001 18.5 0.0 1.7 1 1 0 1 1 1 1 Putative adhesin IgGFc_binding PF17517.2 ABK72584.1 - 0.087 12.1 0.1 0.33 10.2 0.1 1.8 1 1 0 1 1 1 0 IgGFc binding protein DUF1918 PF08940.11 ABK72585.1 - 1.2e-27 95.3 0.4 1.7e-27 94.8 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1918) tRNA_edit PF04073.15 ABK72586.1 - 3.9e-23 81.9 0.4 5.1e-23 81.5 0.4 1.1 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain ABC_tran PF00005.27 ABK72587.1 - 2.9e-29 102.3 0.0 4.5e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK72587.1 - 7.8e-10 39.0 0.0 0.00035 20.5 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 ABK72587.1 - 0.00045 20.0 0.1 0.041 13.6 0.1 2.2 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 ABK72587.1 - 0.0058 16.1 0.0 0.58 9.6 0.1 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ABK72587.1 - 0.0059 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_27 PF13514.6 ABK72587.1 - 0.0071 16.0 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 ABK72587.1 - 0.0093 16.5 0.0 0.015 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 ABK72587.1 - 0.075 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 ABK72587.1 - 0.087 12.4 0.3 0.22 11.1 0.3 1.8 1 1 1 2 2 2 0 AAA domain MukB PF04310.12 ABK72587.1 - 0.1 12.4 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 MukB N-terminal AAA_13 PF13166.6 ABK72587.1 - 0.23 10.1 0.1 0.38 9.4 0.0 1.4 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 ABK72587.1 - 0.27 10.9 0.0 0.55 9.9 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain Myco_19_kDa PF05481.12 ABK72588.1 - 4.5e-24 84.9 1.5 6.5e-24 84.5 1.5 1.2 1 0 0 1 1 1 1 Mycobacterium 19 kDa lipoprotein antigen MFS_4 PF06779.14 ABK72589.1 - 7.7e-67 226.1 51.4 9.3e-67 225.9 51.4 1.0 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1 PF07690.16 ABK72589.1 - 2.1e-14 53.2 60.1 5.4e-10 38.7 49.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Intg_mem_TP0381 PF09529.10 ABK72589.1 - 0.35 10.4 4.5 0.87 9.0 4.5 1.6 1 0 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) TcdA_TcdB_pore PF12920.7 ABK72589.1 - 1.2 7.2 6.4 2 6.6 6.4 1.3 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain SURF1 PF02104.15 ABK72590.1 - 3.1e-26 92.7 0.0 4.6e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 SURF1 family DUF4381 PF14316.6 ABK72590.1 - 0.0064 16.7 0.2 1.6 9.0 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4381) DUF4051 PF13260.6 ABK72590.1 - 0.23 11.2 1.0 17 5.2 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) DUF1232 PF06803.12 ABK72591.1 - 4.8e-13 48.7 9.8 4.8e-13 48.7 9.8 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1232) FAD_binding_3 PF01494.19 ABK72592.1 - 1.8e-17 63.7 0.3 2.8e-15 56.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 ABK72592.1 - 4e-12 45.9 0.1 6.5e-12 45.2 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 ABK72592.1 - 6.2e-11 42.1 1.2 5.6e-06 25.8 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ABK72592.1 - 2.5e-10 40.5 5.4 4.7e-05 23.1 0.4 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 ABK72592.1 - 5.6e-09 35.4 3.5 0.00042 19.3 0.1 2.8 2 1 0 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.14 ABK72592.1 - 1.4e-08 33.9 0.9 6.2e-05 21.9 1.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 ABK72592.1 - 1.5e-06 28.6 0.0 0.0043 17.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ABK72592.1 - 5.9e-06 25.6 2.1 5.9e-06 25.6 2.1 1.7 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 ABK72592.1 - 6.8e-06 25.7 9.1 3e-05 23.5 9.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 ABK72592.1 - 7.2e-06 25.3 1.9 2.2e-05 23.7 1.9 1.7 1 1 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 ABK72592.1 - 3.6e-05 23.9 0.6 0.0001 22.4 0.2 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ABK72592.1 - 0.00084 18.7 0.0 0.026 13.8 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ABK72592.1 - 0.00096 18.5 1.9 0.00096 18.5 1.9 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 ABK72592.1 - 0.012 15.5 0.2 0.018 14.9 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 ABK72592.1 - 0.014 14.6 1.5 0.016 14.5 0.2 1.7 2 0 0 2 2 2 0 Thi4 family XdhC_C PF13478.6 ABK72592.1 - 0.091 13.3 0.3 0.2 12.2 0.3 1.7 1 1 0 1 1 1 0 XdhC Rossmann domain NAD_binding_9 PF13454.6 ABK72592.1 - 0.32 11.0 1.5 11 5.9 0.2 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding BPD_transp_1 PF00528.22 ABK72594.1 - 2.5e-26 92.5 18.3 2.5e-26 92.5 18.3 1.9 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component TssN PF17555.2 ABK72594.1 - 0.94 8.8 5.8 0.35 10.2 2.4 1.9 2 0 0 2 2 2 0 Type VI secretion system, TssN Bac_luciferase PF00296.20 ABK72595.1 - 2.7e-31 109.2 7.6 1.4e-28 100.3 4.4 2.2 2 1 0 2 2 2 2 Luciferase-like monooxygenase NYN PF01936.18 ABK72596.1 - 2.2e-26 93.1 0.5 4.1e-26 92.2 0.5 1.4 1 0 0 1 1 1 1 NYN domain OST-HTH PF12872.7 ABK72596.1 - 1.2e-10 41.0 0.0 1.9e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 OST-HTH/LOTUS domain PIN_11 PF18479.1 ABK72596.1 - 0.07 13.3 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 PIN like domain F420H2_quin_red PF04075.14 ABK72597.1 - 4.7e-23 81.7 0.0 6.2e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase DMRL_synthase PF00885.19 ABK72598.1 - 7.6e-48 161.9 1.8 8.6e-48 161.8 1.8 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase CSD PF00313.22 ABK72599.1 - 9.6e-31 105.4 0.3 1e-30 105.3 0.3 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 ABK72599.1 - 0.00011 21.8 0.2 0.00017 21.2 0.2 1.4 1 0 0 1 1 1 1 Ribonuclease B OB domain HhH-GPD PF00730.25 ABK72600.1 - 1.2e-15 57.9 0.0 1.9e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 ABK72600.1 - 2.4e-08 33.4 0.0 5.3e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 ABK72600.1 - 1.3e-06 28.6 2.1 2.6e-06 27.6 2.1 1.5 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III HHH_5 PF14520.6 ABK72600.1 - 0.016 15.8 0.0 0.029 15.0 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix domain TetR_N PF00440.23 ABK72602.1 - 6.5e-08 32.2 0.1 1.2e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 ABK72602.1 - 3.1e-06 27.4 2.0 6e-05 23.3 0.0 2.9 1 1 1 3 3 3 1 Tetracyclin repressor-like, C-terminal domain TetR_C_11 PF16859.5 ABK72602.1 - 1.8e-05 25.0 0.6 1.8e-05 25.0 0.6 2.7 3 1 1 4 4 4 1 Tetracyclin repressor-like, C-terminal domain TetR_C_27 PF17935.1 ABK72602.1 - 0.00069 19.6 0.0 0.0026 17.8 0.0 2.1 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_6 PF13977.6 ABK72602.1 - 0.016 15.4 0.2 0.016 15.4 0.2 2.9 3 1 1 4 4 4 0 BetI-type transcriptional repressor, C-terminal TetR_C_29 PF17938.1 ABK72602.1 - 0.032 14.3 0.2 0.35 11.0 0.0 2.4 1 1 2 3 3 3 0 Tetracyclin repressor-like, C-terminal domain MMPL PF03176.15 ABK72603.1 - 5.1e-191 633.8 34.6 6.7e-99 331.0 7.1 3.2 3 1 0 3 3 3 2 MMPL family BKACE PF05853.12 ABK72604.1 - 2.2e-32 112.5 0.3 8.4e-32 110.6 0.3 1.7 1 1 0 1 1 1 1 beta-keto acid cleavage enzyme Paf1 PF03985.13 ABK72604.1 - 0.29 10.1 0.1 0.39 9.7 0.1 1.1 1 0 0 1 1 1 0 Paf1 Peripla_BP_2 PF01497.18 ABK72605.1 - 4.1e-28 98.5 0.0 5.8e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein TetR_N PF00440.23 ABK72606.1 - 7.2e-17 60.9 0.1 1.3e-16 60.1 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HAD PF12710.7 ABK72607.1 - 2.5e-33 116.1 0.2 5.6e-33 114.9 0.1 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Acyltransferase PF01553.21 ABK72607.1 - 6.8e-28 97.0 0.0 1.1e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Hydrolase PF00702.26 ABK72607.1 - 0.00014 22.2 0.2 0.0023 18.3 0.2 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ABK72607.1 - 0.05 13.3 0.3 17 5.1 0.0 3.0 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase CMAS PF02353.20 ABK72608.1 - 2.1e-109 365.1 0.0 2.4e-109 364.9 0.0 1.0 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 ABK72608.1 - 6.3e-11 42.4 0.0 9.5e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABK72608.1 - 6.7e-10 39.5 0.0 1.5e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK72608.1 - 1.7e-08 35.1 0.0 3.6e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABK72608.1 - 1e-06 29.3 0.0 1.8e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABK72608.1 - 6.3e-05 22.8 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ABK72608.1 - 0.00029 20.6 0.0 0.00055 19.7 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 ABK72608.1 - 0.034 13.4 0.0 0.064 12.5 0.0 1.5 1 1 0 1 1 1 0 O-methyltransferase domain Methyltransf_4 PF02390.17 ABK72608.1 - 0.047 13.2 0.0 0.27 10.7 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase MetW PF07021.12 ABK72608.1 - 0.069 12.7 0.0 0.39 10.3 0.0 2.0 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 ABK72608.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 ABK72608.1 - 0.19 11.3 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Peripla_BP_4 PF13407.6 ABK72609.1 - 4.6e-53 180.4 9.7 6.1e-53 180.0 9.7 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 ABK72609.1 - 4.1e-14 52.7 0.7 5.6e-14 52.2 0.7 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family ATPgrasp_N PF18130.1 ABK72609.1 - 0.017 15.6 0.1 0.21 12.2 0.0 2.7 3 0 0 3 3 3 0 ATP-grasp N-terminal domain DUF1772 PF08592.11 ABK72610.1 - 0.0015 18.9 0.6 0.0076 16.6 0.4 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) DUF3084 PF11283.8 ABK72610.1 - 0.0024 17.8 2.0 0.78 9.8 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3084) Lin-8 PF03353.15 ABK72610.1 - 0.81 9.2 11.1 1.1 8.8 11.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nitrate_red_gam PF02665.14 ABK72610.1 - 0.82 9.2 5.1 1.2 8.6 5.1 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit BUD22 PF09073.10 ABK72610.1 - 7.4 5.8 24.3 9.6 5.4 24.3 1.1 1 0 0 1 1 1 0 BUD22 GMC_oxred_N PF00732.19 ABK72612.1 - 8.9e-75 251.8 0.0 1.1e-74 251.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ABK72612.1 - 1.2e-31 110.2 0.1 2e-31 109.4 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 ABK72612.1 - 0.00026 20.1 0.0 0.00042 19.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 ABK72612.1 - 0.0036 17.5 0.1 0.011 15.9 0.1 2.0 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ABK72612.1 - 0.0043 16.2 3.0 0.03 13.4 3.0 2.0 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 ABK72612.1 - 0.0089 15.3 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 ABK72612.1 - 0.077 12.6 1.2 0.66 9.5 0.0 2.6 3 1 0 3 3 3 0 FAD dependent oxidoreductase EphA2_TM PF14575.6 ABK72613.1 - 0.058 14.3 0.0 0.058 14.3 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Baculo_11_kDa PF06143.11 ABK72613.1 - 0.19 11.3 0.2 0.29 10.7 0.2 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family Cpn10 PF00166.21 ABK72614.1 - 5.9e-35 119.2 0.2 6.5e-35 119.1 0.2 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit SnoaL_2 PF12680.7 ABK72615.1 - 2.4e-11 44.1 0.1 3.4e-11 43.7 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 ABK72615.1 - 0.023 14.5 0.0 0.041 13.7 0.0 1.4 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase CPBP PF02517.16 ABK72616.1 - 2.5e-14 53.4 6.5 2.5e-14 53.4 6.5 2.2 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease Lactamase_B PF00753.27 ABK72618.1 - 7.9e-17 61.9 10.5 1.2e-16 61.3 10.5 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 ABK72618.1 - 0.0011 18.8 0.1 0.0021 18.0 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 ABK72618.1 - 0.0097 15.4 4.5 0.032 13.7 4.2 1.9 1 1 1 2 2 2 1 Beta-lactamase superfamily domain HTH_31 PF13560.6 ABK72619.1 - 1.1e-11 45.0 1.2 1.1e-11 45.0 1.2 1.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 ABK72619.1 - 1.3e-08 34.7 0.0 1.8e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_25 PF13413.6 ABK72619.1 - 0.00012 21.8 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 ABK72619.1 - 0.00044 20.6 0.0 0.00061 20.2 0.0 1.1 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_19 PF12844.7 ABK72619.1 - 0.012 15.6 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 ABK72619.1 - 0.029 13.9 0.2 0.12 11.9 0.1 2.0 2 1 1 3 3 3 0 Sigma-70, region 4 HTH_17 PF12728.7 ABK72619.1 - 0.14 12.3 0.0 0.74 10.0 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain UvrD_C_2 PF13538.6 ABK72620.1 - 5.8e-08 32.5 0.8 2.8e-07 30.2 0.0 2.5 3 0 0 3 3 3 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 ABK72620.1 - 1.7e-07 31.6 0.0 2.6e-05 24.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 ABK72620.1 - 3.7e-06 26.9 0.0 0.012 15.3 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 ABK72620.1 - 7.7e-06 26.4 0.5 3.3e-05 24.3 0.1 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 ABK72620.1 - 2.8e-05 23.9 0.0 0.00032 20.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 ABK72620.1 - 0.0014 17.9 0.5 0.013 14.7 0.1 2.3 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 ABK72620.1 - 0.0028 17.1 0.2 0.018 14.5 0.1 2.3 3 0 0 3 3 3 1 PhoH-like protein AAA_12 PF13087.6 ABK72620.1 - 0.027 14.1 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 ABK72620.1 - 0.031 13.8 0.1 2.3 7.6 0.0 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain NACHT PF05729.12 ABK72620.1 - 0.041 13.8 0.2 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 NACHT domain CobA_CobO_BtuR PF02572.15 ABK72620.1 - 0.064 13.5 0.0 0.24 11.6 0.0 2.0 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP AAA_22 PF13401.6 ABK72620.1 - 0.075 13.3 0.0 0.89 9.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain PIF1 PF05970.14 ABK72620.1 - 0.079 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase CbiA PF01656.23 ABK72620.1 - 0.1 12.7 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ResIII PF04851.15 ABK72620.1 - 0.15 12.1 0.0 0.54 10.2 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF448 PF04296.13 ABK72621.1 - 1.7e-20 72.6 0.0 2.1e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF448) DUF3079 PF11278.8 ABK72621.1 - 0.06 13.2 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3079) DUF1542 PF07564.11 ABK72623.1 - 0.043 13.9 0.9 0.043 13.9 0.9 1.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) Filament PF00038.21 ABK72623.1 - 0.17 11.5 0.4 0.22 11.1 0.4 1.1 1 0 0 1 1 1 0 Intermediate filament protein DJ-1_PfpI PF01965.24 ABK72624.1 - 1.2e-29 103.2 0.0 1.5e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ABK72624.1 - 0.0012 18.6 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 ThiJ/PfpI family-like Amino_oxidase PF01593.24 ABK72625.1 - 6.5e-16 58.7 4.1 3.5e-14 53.0 4.1 2.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 ABK72625.1 - 1.6e-11 44.4 3.7 8e-07 28.9 0.1 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ABK72625.1 - 1.4e-10 41.3 0.8 3.8e-10 39.9 0.1 2.3 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ABK72625.1 - 7.1e-08 31.6 0.2 0.00093 18.0 0.9 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 ABK72625.1 - 1.3e-07 31.0 2.9 7.2e-05 22.0 1.3 2.3 2 0 0 2 2 2 2 FAD binding domain FAD_binding_3 PF01494.19 ABK72625.1 - 5.3e-05 22.6 1.4 0.0017 17.7 0.2 2.4 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 ABK72625.1 - 0.00032 20.0 0.3 0.00063 19.1 0.3 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 ABK72625.1 - 0.0028 17.1 1.1 0.0028 17.1 1.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ABK72625.1 - 0.0051 16.1 0.5 0.014 14.7 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ABK72625.1 - 0.007 15.5 2.8 0.0093 15.1 1.2 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 ABK72625.1 - 0.025 15.1 0.1 0.086 13.4 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 ABK72625.1 - 0.037 13.4 0.7 1.4 8.2 0.2 2.2 2 0 0 2 2 2 0 GMC oxidoreductase XdhC_C PF13478.6 ABK72625.1 - 0.047 14.2 0.2 0.32 11.5 0.0 2.3 2 0 0 2 2 2 0 XdhC Rossmann domain UDPG_MGDP_dh_N PF03721.14 ABK72625.1 - 0.065 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.6 ABK72625.1 - 0.28 10.4 0.4 0.44 9.7 0.4 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ABK72625.1 - 1.2 8.1 4.1 0.82 8.6 1.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 ABK72625.1 - 3 7.1 6.3 0.14 11.5 0.4 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain AsnC_trans_reg PF01037.21 ABK72626.1 - 1.2e-11 44.4 0.1 0.00021 21.2 0.1 2.7 3 0 0 3 3 3 2 Lrp/AsnC ligand binding domain HTH_AsnC-type PF13404.6 ABK72626.1 - 1.8e-09 37.3 9.4 2.9e-06 27.0 1.0 2.6 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 ABK72626.1 - 1.7e-06 27.5 0.4 0.013 15.0 0.0 2.4 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 ABK72626.1 - 0.00065 19.5 8.0 0.045 13.7 0.6 3.5 2 1 1 3 3 3 2 MarR family HTH_28 PF13518.6 ABK72626.1 - 0.00075 19.6 5.1 0.55 10.4 0.1 2.9 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_23 PF13384.6 ABK72626.1 - 0.0071 16.1 1.8 1.9 8.4 0.3 2.5 2 0 0 2 2 2 2 Homeodomain-like domain HTH_Crp_2 PF13545.6 ABK72626.1 - 0.014 15.4 0.2 1.8 8.6 0.1 2.6 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Sigma70_r4_2 PF08281.12 ABK72626.1 - 0.02 14.5 0.3 0.33 10.7 0.1 2.6 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_5 PF01022.20 ABK72626.1 - 0.032 14.1 0.0 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family DUF4081 PF13312.6 ABK72626.1 - 0.11 12.7 5.4 0.25 11.6 0.1 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4081) HTH_29 PF13551.6 ABK72626.1 - 0.31 11.1 6.2 0.85 9.7 0.1 3.1 3 0 0 3 3 3 0 Winged helix-turn helix WXG100 PF06013.12 ABK72627.1 - 9.3e-10 38.6 2.3 1.1e-09 38.4 2.3 1.1 1 0 0 1 1 1 1 Proteins of 100 residues with WXG DUF5315 PF17242.2 ABK72627.1 - 0.0068 16.2 0.4 0.011 15.6 0.4 1.4 1 0 0 1 1 1 1 Disordered region of unknown function (DUF5315) Apolipoprotein PF01442.18 ABK72627.1 - 0.018 14.9 1.6 0.02 14.8 1.6 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain HSCB_C PF07743.13 ABK72627.1 - 0.079 13.5 1.3 0.12 12.9 1.3 1.3 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain Methyltransf_11 PF08241.12 ABK72628.1 - 2.9e-10 40.7 0.0 1.2e-09 38.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABK72628.1 - 3.1e-08 34.2 0.0 6.3e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABK72628.1 - 0.0052 16.6 0.0 0.012 15.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 ABK72628.1 - 0.052 13.0 0.0 0.074 12.4 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_12 PF08242.12 ABK72628.1 - 0.12 13.1 0.0 0.38 11.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain MiaE_2 PF13794.6 ABK72629.1 - 1.2e-62 210.9 5.8 1.7e-62 210.5 5.8 1.1 1 0 0 1 1 1 1 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like MiaE PF06175.11 ABK72629.1 - 0.00031 20.4 0.4 0.00042 20.0 0.4 1.3 1 0 0 1 1 1 1 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) CPSase_L_D2 PF02786.17 ABK72630.1 - 9.4e-66 221.3 0.1 1.7e-65 220.5 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 ABK72630.1 - 6e-55 186.1 0.0 1.6e-54 184.7 0.0 1.7 2 0 0 2 2 2 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 ABK72630.1 - 1.1e-40 138.6 0.1 3.1e-40 137.2 0.1 1.9 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ABK72630.1 - 7.2e-36 122.6 0.0 1.8e-35 121.3 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 ABK72630.1 - 2.7e-28 99.3 0.0 4.9e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 ABK72630.1 - 6e-16 58.0 0.3 1.3e-15 57.0 0.3 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 ABK72630.1 - 8.2e-07 28.8 0.0 1.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 ABK72630.1 - 4.4e-06 26.4 0.8 0.0016 18.3 0.1 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 ABK72630.1 - 0.0039 17.3 0.0 0.006 16.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.6 ABK72630.1 - 0.019 14.9 0.1 0.053 13.5 0.1 1.7 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain HlyD_3 PF13437.6 ABK72630.1 - 0.051 14.3 3.1 2.2 9.0 0.3 2.9 2 1 1 3 3 2 0 HlyD family secretion protein GCV_H PF01597.19 ABK72630.1 - 0.14 12.0 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein HlyD_D23 PF16576.5 ABK72630.1 - 0.16 11.1 0.2 3.5 6.8 0.0 2.2 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion PDT PF00800.18 ABK72631.1 - 1.2e-44 152.3 0.0 1.7e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 ABK72631.1 - 3.8e-08 33.0 0.0 1e-07 31.6 0.0 1.8 2 0 0 2 2 2 1 ACT domain PBP_like PF12727.7 ABK72631.1 - 0.0017 17.5 0.4 0.0089 15.2 0.3 2.0 2 0 0 2 2 2 1 PBP superfamily domain SBP_bac_3 PF00497.20 ABK72631.1 - 0.0018 17.8 0.0 0.11 11.9 0.0 2.2 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 ABK72631.1 - 0.059 12.9 1.0 8.5 5.9 0.0 2.3 1 1 0 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein AMP-binding PF00501.28 ABK72632.1 - 1.4e-76 257.9 0.0 1.6e-76 257.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK72632.1 - 4.9e-18 65.9 0.4 9.4e-18 65.0 0.4 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Bac_luciferase PF00296.20 ABK72633.1 - 7.9e-57 193.0 13.0 1e-56 192.7 13.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase PHP PF02811.19 ABK72633.1 - 0.11 12.7 0.0 17 5.7 0.0 2.3 2 0 0 2 2 2 0 PHP domain FAD_binding_2 PF00890.24 ABK72635.1 - 1.1e-91 308.0 3.6 1.3e-91 307.8 3.6 1.0 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 ABK72635.1 - 6.5e-07 29.0 1.7 1.1e-06 28.3 1.7 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 ABK72635.1 - 0.00042 19.6 0.6 0.0012 18.1 0.2 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 ABK72635.1 - 0.00094 19.4 2.1 0.046 14.0 0.7 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ABK72635.1 - 0.0018 17.0 0.1 0.0029 16.4 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 ABK72635.1 - 0.25 10.4 0.4 0.66 9.0 0.3 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A MacB_PCD PF12704.7 ABK72636.1 - 0.0031 17.9 4.9 0.0031 17.9 4.9 2.7 2 1 0 2 2 2 1 MacB-like periplasmic core domain NKAIN PF05640.14 ABK72636.1 - 0.14 11.4 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Na,K-Atpase Interacting protein FtsX PF02687.21 ABK72636.1 - 0.85 10.1 18.3 0.1 13.1 6.1 3.4 3 1 0 3 3 3 0 FtsX-like permease family DUF4064 PF13273.6 ABK72636.1 - 9.1 6.6 11.9 3.4 8.0 7.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) TetR_N PF00440.23 ABK72637.1 - 1.2e-07 31.3 0.0 3.2e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_15 PF17918.1 ABK72637.1 - 0.012 16.4 1.7 0.015 16.1 0.7 1.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HTH_AraC PF00165.23 ABK72637.1 - 0.025 14.7 0.5 0.058 13.5 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family DUF826 PF05696.11 ABK72637.1 - 0.069 13.2 0.2 2.4 8.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF826) Amidase PF01425.21 ABK72638.1 - 1.1e-96 324.6 7.5 3.7e-76 256.9 7.7 2.0 1 1 0 2 2 2 2 Amidase DinB_2 PF12867.7 ABK72638.1 - 0.093 13.2 1.0 0.33 11.5 0.0 2.3 2 1 0 2 2 2 0 DinB superfamily DUF1348 PF07080.11 ABK72639.1 - 2.2e-66 221.7 4.5 2.5e-66 221.5 4.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 ABK72639.1 - 6.3e-08 33.2 1.0 8.5e-08 32.8 1.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 ABK72639.1 - 0.029 14.8 0.1 0.037 14.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) SnoaL PF07366.12 ABK72639.1 - 0.039 13.8 0.1 0.052 13.4 0.1 1.2 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase RR_TM4-6 PF06459.12 ABK72640.1 - 1.5 8.6 5.6 2.2 8.0 5.6 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sigma70_r2 PF04542.14 ABK72641.1 - 3.3e-18 65.2 1.5 5.4e-18 64.5 0.5 1.8 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 ABK72641.1 - 5.4e-17 61.2 0.0 8.9e-17 60.5 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 ABK72641.1 - 1.9e-10 40.1 0.1 3.2e-10 39.4 0.1 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 ABK72641.1 - 0.00068 19.4 0.5 0.0016 18.1 0.1 1.9 2 0 0 2 2 2 1 Homeodomain-like domain CT_C_D PF02682.16 ABK72641.1 - 0.028 14.2 0.1 0.042 13.6 0.1 1.2 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D HTH_AsnC-type PF13404.6 ABK72641.1 - 0.056 13.3 0.0 0.21 11.4 0.0 2.0 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 ABK72641.1 - 0.19 11.3 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding CarD_CdnL_TRCF PF02559.16 ABK72642.1 - 2.4e-20 73.0 0.1 3.2e-20 72.6 0.1 1.2 1 0 0 1 1 1 1 CarD-like/TRCF domain DUF4012 PF13196.6 ABK72642.1 - 0.071 13.6 0.0 0.11 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4012) TetR_N PF00440.23 ABK72643.1 - 2.9e-10 39.8 0.2 1.3e-09 37.7 0.1 2.2 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_13 PF16925.5 ABK72643.1 - 0.00014 21.8 0.0 0.00024 21.0 0.0 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Guanylate_cyc PF00211.20 ABK72645.1 - 5.3e-20 71.8 0.0 8.6e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HAMP PF00672.25 ABK72645.1 - 1.4e-08 35.0 0.1 3.6e-08 33.7 0.1 1.8 1 0 0 1 1 1 1 HAMP domain DNA_gyraseB PF00204.25 ABK72646.1 - 1.6e-61 206.8 0.1 2.4e-61 206.2 0.1 1.3 1 0 0 1 1 1 1 DNA gyrase B DNA_gyraseB_C PF00986.21 ABK72646.1 - 2.5e-26 91.6 0.0 5.1e-26 90.6 0.0 1.5 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 ABK72646.1 - 8.7e-21 74.5 0.0 1.8e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 ABK72646.1 - 1.1e-16 60.9 0.0 2.5e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 Toprim domain HATPase_c_3 PF13589.6 ABK72646.1 - 0.039 13.8 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ECH_1 PF00378.20 ABK72647.1 - 1.4e-29 103.2 0.0 1.6e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK72647.1 - 3.1e-08 33.5 0.0 4e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Aldedh PF00171.22 ABK72648.1 - 5.1e-160 533.0 0.0 5.8e-160 532.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 ABK72648.1 - 0.0061 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) VapB_antitoxin PF09957.9 ABK72649.1 - 0.0019 18.1 0.4 0.0051 16.7 0.4 1.7 1 0 0 1 1 1 1 Bacterial antitoxin of type II TA system, VapB UTRA PF07702.13 ABK72651.1 - 3e-28 98.4 0.9 7.1e-28 97.2 0.1 1.8 2 0 0 2 2 2 1 UTRA domain GntR PF00392.21 ABK72651.1 - 6.1e-12 45.0 0.6 1.3e-11 43.9 0.6 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_28 PF13518.6 ABK72651.1 - 0.0022 18.1 0.2 0.28 11.3 0.1 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 ABK72651.1 - 0.0034 17.3 0.2 0.0072 16.3 0.2 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain TrmB PF01978.19 ABK72651.1 - 0.0068 16.3 0.1 0.016 15.0 0.1 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Sigma70_r4 PF04545.16 ABK72651.1 - 0.0083 15.6 1.2 0.077 12.5 0.4 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_DeoR PF08220.12 ABK72651.1 - 0.089 12.6 0.5 0.16 11.7 0.5 1.4 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain BLACT_WH PF17778.1 ABK72651.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase associated winged helix domain Amidase_2 PF01510.25 ABK72652.1 - 1.2e-12 48.4 0.2 1.7e-12 47.9 0.2 1.2 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase TetR_N PF00440.23 ABK72653.1 - 7.4e-16 57.7 0.9 3.4e-15 55.6 0.9 2.2 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family Abhydrolase_9_N PF15420.6 ABK72653.1 - 0.0073 16.3 0.6 0.012 15.6 0.1 1.6 2 0 0 2 2 2 1 Alpha/beta-hydrolase family N-terminus MotA_ExbB PF01618.16 ABK72653.1 - 0.052 13.3 0.2 0.24 11.1 0.0 2.0 1 1 1 2 2 2 0 MotA/TolQ/ExbB proton channel family Response_reg PF00072.24 ABK72654.1 - 1e-27 96.5 0.0 1.9e-27 95.6 0.0 1.5 2 0 0 2 2 2 1 Response regulator receiver domain Trans_reg_C PF00486.28 ABK72654.1 - 1.2e-24 86.2 0.0 7.5e-24 83.6 0.0 2.0 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal FleQ PF06490.11 ABK72654.1 - 0.005 17.2 0.0 0.0078 16.6 0.0 1.3 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ 3HCDH_RFF PF18321.1 ABK72654.1 - 0.049 14.1 0.2 1.4 9.4 0.1 2.5 2 0 0 2 2 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain B12-binding PF02310.19 ABK72654.1 - 0.07 13.2 0.1 0.17 11.9 0.0 1.6 2 0 0 2 2 2 0 B12 binding domain Peptidase_S9_N PF02897.15 ABK72655.1 - 4.8e-116 388.0 0.0 5.8e-116 387.7 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 ABK72655.1 - 9.7e-67 224.5 0.0 1.5e-66 223.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 ABK72655.1 - 0.0024 17.8 0.0 0.0043 16.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ABK72655.1 - 0.19 10.9 0.0 0.34 10.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DAO PF01266.24 ABK72656.1 - 1.4e-35 123.5 8.0 1.7e-35 123.3 8.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ABK72656.1 - 1.6e-06 27.6 0.6 2.6e-05 23.6 0.6 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ABK72656.1 - 1.2e-05 24.6 0.3 0.033 13.3 0.2 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 ABK72656.1 - 3.9e-05 23.8 0.1 0.00013 22.1 0.1 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ABK72656.1 - 0.00018 20.7 7.4 0.00089 18.4 7.2 2.1 1 1 0 1 1 1 1 FAD binding domain ApbA PF02558.16 ABK72656.1 - 0.00044 19.9 0.1 0.0029 17.3 0.1 2.1 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 ABK72656.1 - 0.00075 20.0 0.5 0.0017 18.8 0.5 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 ABK72656.1 - 0.002 18.5 0.0 0.0034 17.8 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 ABK72656.1 - 0.0029 16.9 0.8 0.0068 15.7 0.8 1.6 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 ABK72656.1 - 0.0029 16.9 0.5 0.0056 16.0 0.5 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 ABK72656.1 - 0.0093 14.7 0.2 0.49 9.0 0.3 2.2 2 0 0 2 2 2 1 HI0933-like protein UDPG_MGDP_dh_N PF03721.14 ABK72656.1 - 0.01 15.4 0.2 0.02 14.5 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.17 ABK72656.1 - 0.011 15.0 0.2 0.017 14.4 0.2 1.3 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.24 ABK72656.1 - 0.011 15.0 0.5 2.8 7.1 0.1 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 ABK72656.1 - 0.022 14.7 2.7 3.2 7.7 0.3 2.6 2 1 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 ABK72656.1 - 0.052 12.4 1.4 5.7 5.7 1.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.18 ABK72656.1 - 0.1 12.5 1.0 0.17 11.7 0.4 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 ABK72656.1 - 0.1 11.6 1.5 4.8 6.1 0.8 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein ThiF PF00899.21 ABK72656.1 - 0.19 11.1 0.9 0.35 10.2 0.9 1.4 1 0 0 1 1 1 0 ThiF family FAD_oxidored PF12831.7 ABK72656.1 - 0.23 10.8 6.1 0.079 12.3 1.4 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase GntR PF00392.21 ABK72657.1 - 5.2e-20 70.9 2.0 1.2e-19 69.7 0.9 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family FCD PF07729.12 ABK72657.1 - 1.1e-08 35.5 4.5 1.1e-08 35.5 4.5 2.1 2 0 0 2 2 2 1 FCD domain MarR_2 PF12802.7 ABK72657.1 - 2.8e-06 27.1 0.2 2.8e-06 27.1 0.2 2.6 3 0 0 3 3 3 1 MarR family Fe_dep_repress PF01325.19 ABK72657.1 - 2.2e-05 24.5 0.0 4.1e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_24 PF13412.6 ABK72657.1 - 2.6e-05 23.7 0.3 5.5e-05 22.6 0.1 1.6 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 ABK72657.1 - 7.7e-05 22.5 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 ABK72657.1 - 0.00023 21.0 0.1 0.00045 20.1 0.1 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_11 PF08279.12 ABK72657.1 - 0.00027 20.8 0.1 0.00069 19.5 0.1 1.6 1 0 0 1 1 1 1 HTH domain MarR PF01047.22 ABK72657.1 - 0.0014 18.5 0.0 0.0049 16.8 0.0 1.9 2 0 0 2 2 1 1 MarR family Rrf2 PF02082.20 ABK72657.1 - 0.002 18.4 0.0 0.0039 17.5 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator HTH_27 PF13463.6 ABK72657.1 - 0.0022 18.5 0.0 0.005 17.3 0.0 1.6 1 0 0 1 1 1 1 Winged helix DNA-binding domain PaaX PF07848.12 ABK72657.1 - 0.0032 17.7 0.1 0.0082 16.3 0.1 1.6 1 0 0 1 1 1 1 PaaX-like protein HTH_AsnC-type PF13404.6 ABK72657.1 - 0.0038 17.0 1.0 0.0084 15.9 1.0 1.6 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_20 PF12840.7 ABK72657.1 - 0.0059 16.7 0.1 0.021 14.9 0.1 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 ABK72657.1 - 0.0087 15.9 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_29 PF13551.6 ABK72657.1 - 0.012 15.6 0.0 0.029 14.4 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix HTH_36 PF13730.6 ABK72657.1 - 0.012 15.5 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain RP-C PF03428.13 ABK72657.1 - 0.017 14.8 0.3 0.043 13.5 0.3 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain HTH_23 PF13384.6 ABK72657.1 - 0.038 13.8 0.1 0.082 12.7 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 ABK72657.1 - 0.069 13.3 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain TFIIE_alpha PF02002.17 ABK72657.1 - 0.088 12.7 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 TFIIE alpha subunit HTH_50 PF18024.1 ABK72657.1 - 0.16 11.6 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HEAT_2 PF13646.6 ABK72657.1 - 0.17 12.3 5.2 0.074 13.5 1.3 2.4 2 1 0 2 2 2 0 HEAT repeats Lip_A_acyltrans PF03279.13 ABK72658.1 - 1.9e-85 286.6 0.0 2.3e-85 286.4 0.0 1.0 1 0 0 1 1 1 1 Bacterial lipid A biosynthesis acyltransferase AMP-binding PF00501.28 ABK72659.1 - 1.5e-84 284.1 0.0 1.9e-84 283.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK72659.1 - 6.9e-17 62.2 0.2 2.5e-16 60.4 0.2 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BaxI_1 PF12811.7 ABK72660.1 - 4.2e-83 278.5 11.2 4.5e-83 278.4 11.2 1.0 1 0 0 1 1 1 1 Bax inhibitor 1 like Bax1-I PF01027.20 ABK72660.1 - 5e-19 69.0 23.8 6.6e-19 68.6 23.8 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 HisKA_7TM PF16927.5 ABK72660.1 - 0.0018 18.3 13.4 0.0018 18.3 13.4 1.7 2 1 0 2 2 2 1 N-terminal 7TM region of histidine kinase DUF3487 PF11990.8 ABK72660.1 - 0.0087 15.9 0.8 0.0087 15.9 0.8 3.1 2 1 2 4 4 4 1 Protein of unknown function (DUF3487) Ndc1_Nup PF09531.10 ABK72660.1 - 1.6 7.3 4.2 0.51 9.0 0.5 1.8 1 1 1 2 2 2 0 Nucleoporin protein Ndc1-Nup NTP_transf_2 PF01909.23 ABK72661.1 - 2.8e-08 33.9 0.0 4.4e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 ABK72661.1 - 2.5e-06 27.5 0.0 4.3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase TauE PF01925.19 ABK72662.1 - 8.1e-30 104.2 37.0 9.7e-30 103.9 37.0 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE FAD_binding_6 PF00970.24 ABK72663.1 - 9.4e-15 54.8 0.0 1.5e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 ABK72663.1 - 8.4e-08 32.8 0.0 4.1e-07 30.6 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 ABK72663.1 - 2e-06 28.3 0.0 3.3e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Globin ADC PF06314.11 ABK72664.1 - 2.7e-42 145.0 0.2 3.4e-42 144.6 0.2 1.0 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Sigma70_r4 PF04545.16 ABK72665.1 - 8.1e-19 66.9 5.5 4.8e-18 64.4 1.4 3.1 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_r3 PF04539.16 ABK72665.1 - 2.4e-14 53.2 0.2 2.4e-12 46.7 0.0 2.4 2 0 0 2 2 2 1 Sigma-70 region 3 Sigma70_r2 PF04542.14 ABK72665.1 - 3.7e-14 52.2 0.0 7.1e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 ABK72665.1 - 6.8e-11 41.7 2.0 9.5e-11 41.2 1.0 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.6 ABK72665.1 - 0.0002 21.0 1.1 0.00081 19.1 0.1 2.3 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.7 ABK72665.1 - 0.00027 20.8 1.5 0.077 12.9 0.1 2.7 2 0 0 2 2 2 2 MarR family HTH_Crp_2 PF13545.6 ABK72665.1 - 0.00047 20.1 1.7 0.0035 17.3 0.3 2.4 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_24 PF13412.6 ABK72665.1 - 0.00087 18.8 0.3 0.01 15.4 0.0 2.6 2 1 0 2 2 2 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 ABK72665.1 - 0.0016 18.3 0.0 0.0072 16.2 0.0 1.9 2 0 0 2 2 2 1 MarR family HTH_3 PF01381.22 ABK72665.1 - 0.0038 17.2 0.2 0.017 15.2 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix Sigma70_ECF PF07638.11 ABK72665.1 - 0.0081 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 ECF sigma factor YdaS_antitoxin PF15943.5 ABK72665.1 - 0.018 14.9 0.1 0.25 11.3 0.0 2.4 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT TetR_C_11 PF16859.5 ABK72665.1 - 0.019 15.3 1.8 0.73 10.2 0.2 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HTH_37 PF13744.6 ABK72665.1 - 0.023 14.7 0.0 0.09 12.7 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_20 PF12840.7 ABK72665.1 - 0.059 13.4 1.5 7.2 6.7 0.2 3.2 2 1 0 2 2 2 0 Helix-turn-helix domain Phage_antitermQ PF06530.12 ABK72665.1 - 0.08 12.9 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 Phage antitermination protein Q GerE PF00196.19 ABK72665.1 - 0.1 12.2 0.1 0.22 11.1 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_IclR PF09339.10 ABK72665.1 - 0.11 12.3 4.1 0.65 9.8 0.4 3.2 3 1 0 3 3 3 0 IclR helix-turn-helix domain KORA PF16509.5 ABK72665.1 - 0.12 12.7 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor HTH_31 PF13560.6 ABK72665.1 - 0.14 12.5 0.2 0.14 12.5 0.2 3.0 3 2 1 4 4 4 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 ABK72665.1 - 0.15 11.9 3.7 2.2 8.2 0.0 3.8 4 1 0 4 4 3 0 AsnC-type helix-turn-helix domain Abhydrolase_1 PF00561.20 ABK72666.1 - 1e-13 51.6 0.0 1.5e-12 47.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ABK72666.1 - 0.13 11.6 0.0 2.3 7.4 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 MFS_1 PF07690.16 ABK72667.1 - 2e-35 122.3 59.7 5e-33 114.5 40.9 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily OATP PF03137.20 ABK72667.1 - 3e-06 25.8 11.0 0.00011 20.6 0.2 3.1 1 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 ABK72667.1 - 0.038 12.8 10.8 0.1 11.4 3.4 3.0 2 1 1 3 3 3 0 MFS_1 like family Carla_C4 PF01623.17 ABK72668.1 - 0.058 13.3 0.3 0.1 12.6 0.3 1.4 1 1 0 1 1 1 0 Carlavirus putative nucleic acid binding protein ArsA_ATPase PF02374.15 ABK72669.1 - 4.5e-23 81.9 0.0 1.7e-15 57.1 0.0 2.1 1 1 0 2 2 2 2 Anion-transporting ATPase CbiA PF01656.23 ABK72669.1 - 3.9e-11 43.1 0.0 2.1e-10 40.8 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 ABK72669.1 - 1.4e-07 31.3 0.1 5.9e-07 29.2 0.1 2.0 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase AAA_31 PF13614.6 ABK72669.1 - 1.4e-07 31.6 0.0 7.7e-06 25.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 ABK72669.1 - 7.3e-07 28.7 0.8 2.8e-05 23.5 0.1 2.6 3 0 0 3 3 3 1 ATPase MipZ CBP_BcsQ PF06564.12 ABK72669.1 - 9.8e-05 21.9 0.0 0.00016 21.2 0.0 1.3 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 ABK72669.1 - 0.00014 21.5 1.0 0.00024 20.8 0.2 1.8 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.18 ABK72669.1 - 0.0004 19.9 0.0 0.00067 19.2 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.11 ABK72669.1 - 0.0005 19.4 0.1 0.0041 16.4 0.0 2.1 2 0 0 2 2 2 1 VirC1 protein AAA_30 PF13604.6 ABK72669.1 - 0.00078 19.2 0.3 0.002 17.9 0.3 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 ABK72669.1 - 0.0026 17.1 0.1 0.0065 15.8 0.0 1.6 2 0 0 2 2 2 1 KaiC IstB_IS21 PF01695.17 ABK72669.1 - 0.0039 17.0 0.1 0.0075 16.0 0.1 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 ABK72669.1 - 0.012 16.0 1.9 0.015 15.7 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain APS_kinase PF01583.20 ABK72669.1 - 0.013 15.4 0.3 0.076 12.9 0.1 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase PhoH PF02562.16 ABK72669.1 - 0.013 14.9 0.1 0.026 14.0 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein SRP54 PF00448.22 ABK72669.1 - 0.027 14.1 0.1 0.69 9.5 0.1 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PIF1 PF05970.14 ABK72669.1 - 0.029 13.5 0.0 0.048 12.8 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_22 PF13401.6 ABK72669.1 - 0.031 14.6 0.1 0.16 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 ABK72669.1 - 0.032 14.0 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MeaB PF03308.16 ABK72669.1 - 0.036 13.0 0.1 0.073 12.0 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB T2SSE PF00437.20 ABK72669.1 - 0.036 13.1 0.0 0.071 12.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.9 ABK72669.1 - 0.075 12.3 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 ABK72669.1 - 0.087 12.1 0.1 0.16 11.2 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin Helicase_RecD PF05127.14 ABK72669.1 - 0.096 12.5 0.0 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 Helicase CLP1_P PF16575.5 ABK72669.1 - 0.12 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_23 PF13476.6 ABK72669.1 - 0.13 12.8 0.1 0.32 11.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain DUF4089 PF13318.6 ABK72669.1 - 0.96 10.0 5.9 2.6 8.6 0.9 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4089) Amino_oxidase PF01593.24 ABK72670.1 - 8.7e-39 134.1 0.5 1e-38 133.8 0.5 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 ABK72670.1 - 6.3e-15 55.2 0.3 1.5e-06 27.7 1.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ABK72670.1 - 6.7e-13 48.7 1.3 2.4e-12 46.9 1.3 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ABK72670.1 - 1.4e-12 47.9 2.7 3.5e-12 46.6 2.7 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 ABK72670.1 - 1.5e-09 38.2 1.5 0.00017 22.0 3.8 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ABK72670.1 - 1e-08 34.3 0.3 0.00018 20.4 1.9 2.2 2 0 0 2 2 2 2 HI0933-like protein MCRA PF06100.11 ABK72670.1 - 3.9e-08 32.5 0.0 0.0064 15.3 0.0 2.0 2 0 0 2 2 2 2 MCRA family FAD_oxidored PF12831.7 ABK72670.1 - 4.4e-08 32.9 0.8 6.4e-08 32.4 0.8 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ABK72670.1 - 4.1e-07 29.4 3.4 4.1e-07 29.4 3.4 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 ABK72670.1 - 7.8e-07 29.2 2.2 0.015 15.3 0.0 2.6 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 ABK72670.1 - 4.9e-05 22.7 0.3 0.029 13.6 0.8 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ABK72670.1 - 5.5e-05 22.6 1.0 8.8e-05 21.9 1.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 ABK72670.1 - 6.8e-05 22.2 0.8 0.00012 21.5 0.8 1.3 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 ABK72670.1 - 0.00052 19.4 0.6 0.001 18.4 0.6 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 ABK72670.1 - 0.00062 18.9 2.0 0.0011 18.1 2.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 ABK72670.1 - 0.00078 18.6 0.3 0.019 14.1 0.3 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein FMO-like PF00743.19 ABK72670.1 - 0.013 14.0 0.0 0.017 13.5 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like UDPG_MGDP_dh_N PF03721.14 ABK72670.1 - 0.026 14.1 0.2 0.037 13.6 0.2 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 ABK72670.1 - 0.061 13.2 1.2 0.1 12.5 1.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 ABK72670.1 - 0.18 10.6 4.0 0.28 10.0 3.4 1.6 2 0 0 2 2 2 0 Tryptophan halogenase PDGLE PF13190.6 ABK72671.1 - 0.18 11.7 0.5 1 9.3 0.0 2.3 2 0 0 2 2 2 0 PDGLE domain Acyltransferase PF01553.21 ABK72672.1 - 1.1e-30 106.0 0.0 1.5e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Aminotran_3 PF00202.21 ABK72673.1 - 5e-74 249.4 0.0 6.5e-74 249.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Citrate_synt PF00285.21 ABK72674.1 - 8e-138 459.4 0.0 9.4e-138 459.2 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Mlf1IP PF10248.9 ABK72674.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein DHquinase_I PF01487.15 ABK72674.1 - 0.19 12.0 0.0 0.5 10.6 0.0 1.6 2 1 0 2 2 2 0 Type I 3-dehydroquinase sCache_3_2 PF17203.4 ABK72675.1 - 9.1e-26 90.7 0.6 9.1e-26 90.7 0.6 2.6 3 0 0 3 3 3 1 Single cache domain 3 HATPase_c PF02518.26 ABK72675.1 - 3.2e-18 66.3 0.0 7.1e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 ABK72675.1 - 5.5e-14 51.9 0.0 1.1e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 ABK72675.1 - 6.3e-09 35.9 0.5 3e-08 33.7 0.1 2.3 2 1 1 3 3 3 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 ABK72675.1 - 5.4e-06 26.3 0.0 9.8e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 ABK72675.1 - 8.5e-06 25.7 0.0 2.4e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 PAS domain SPOB_a PF14689.6 ABK72675.1 - 0.0013 18.4 0.0 0.0028 17.3 0.0 1.5 1 0 0 1 1 1 1 Sensor_kinase_SpoOB-type, alpha-helical domain dCache_1 PF02743.18 ABK72675.1 - 0.0017 18.2 0.0 0.013 15.3 0.0 2.0 2 0 0 2 2 2 1 Cache domain dCache_3 PF14827.6 ABK72675.1 - 0.0077 15.9 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Double sensory domain of two-component sensor kinase PAS PF00989.25 ABK72675.1 - 0.008 16.2 0.0 0.028 14.4 0.0 2.0 2 0 0 2 2 2 1 PAS fold sCache_3_3 PF17202.4 ABK72675.1 - 0.086 13.3 0.0 0.43 11.0 0.0 2.3 2 0 0 2 2 2 0 Single cache domain 3 COX8 PF02285.15 ABK72675.1 - 0.25 11.2 0.7 0.87 9.5 0.7 1.9 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIII MHYT PF03707.16 ABK72675.1 - 0.28 11.4 3.6 1.9 8.7 0.6 2.8 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat Pyr_redox_2 PF07992.14 ABK72676.1 - 1.2e-31 110.1 0.4 2.4e-31 109.0 0.4 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ABK72676.1 - 2.4e-16 59.9 0.4 6.2e-11 42.1 0.0 2.9 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Response_reg PF00072.24 ABK72676.1 - 9.2e-14 51.6 0.0 2.1e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Pyr_redox PF00070.27 ABK72676.1 - 3.1e-07 30.8 3.4 9.9e-05 22.8 0.0 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ABK72676.1 - 3e-06 26.9 12.4 8.8e-06 25.3 4.1 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ABK72676.1 - 4.8e-06 25.9 11.6 0.00014 21.1 4.1 3.3 2 1 0 3 3 3 2 FAD binding domain DAO PF01266.24 ABK72676.1 - 8.4e-06 25.6 11.4 0.011 15.3 0.2 2.7 2 1 1 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.22 ABK72676.1 - 1.1e-05 24.7 6.6 0.00049 19.3 0.4 3.9 4 1 0 4 4 4 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 ABK72676.1 - 4.6e-05 22.8 1.4 0.0032 16.8 0.4 2.4 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 ABK72676.1 - 9e-05 21.8 3.2 0.0013 18.0 0.3 2.8 3 0 0 3 3 3 1 Thi4 family HI0933_like PF03486.14 ABK72676.1 - 0.00048 19.0 4.8 0.00057 18.7 0.6 2.4 3 0 0 3 3 3 1 HI0933-like protein Lycopene_cycl PF05834.12 ABK72676.1 - 0.00083 18.5 2.3 0.032 13.3 0.5 2.5 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 ABK72676.1 - 0.00091 19.2 3.6 0.019 14.9 0.3 2.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 ABK72676.1 - 0.0011 19.1 5.2 0.0023 18.1 2.2 2.8 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 ABK72676.1 - 0.0029 16.8 0.1 0.67 9.0 0.0 2.9 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) CoA_binding_3 PF13727.6 ABK72676.1 - 0.093 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 CoA-binding domain 2-Hacid_dh_C PF02826.19 ABK72677.1 - 6.8e-42 142.8 0.0 8.9e-42 142.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 ABK72677.1 - 4.5e-06 26.9 0.0 6.9e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.21 ABK72677.1 - 3.1e-05 23.4 0.3 0.00014 21.3 0.2 1.9 2 0 0 2 2 2 1 ThiF family F420_oxidored PF03807.17 ABK72677.1 - 0.00011 22.7 0.1 0.00046 20.7 0.1 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 ABK72677.1 - 0.0034 17.5 0.0 0.0061 16.6 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 ABK72677.1 - 0.0035 17.3 0.5 0.017 15.0 0.4 2.0 2 0 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 ABK72677.1 - 0.004 16.6 0.1 0.0076 15.7 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase ApbA PF02558.16 ABK72677.1 - 0.092 12.4 2.4 0.099 12.3 0.9 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA adh_short_C2 PF13561.6 ABK72677.1 - 0.14 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DpaA_N PF16924.5 ABK72677.1 - 0.16 12.0 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 Dipicolinate synthase subunit A N-terminal domain SIS PF01380.22 ABK72677.1 - 0.2 11.5 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 SIS domain GHMP_kinases_N PF00288.26 ABK72678.1 - 2.3e-11 43.7 1.0 2.3e-11 43.7 1.0 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 ABK72678.1 - 8.7e-06 26.0 0.7 1.9e-05 25.0 0.2 1.8 2 0 0 2 2 2 1 GHMP kinases C terminal adh_short PF00106.25 ABK72679.1 - 2.6e-46 157.5 0.9 4.4e-46 156.8 0.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK72679.1 - 3.6e-45 154.4 2.2 7.1e-45 153.4 2.2 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase FAD_binding_6 PF00970.24 ABK72679.1 - 1.1e-18 67.4 0.0 2.7e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 ABK72679.1 - 6.3e-18 65.4 0.0 1.4e-17 64.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FCD PF07729.12 ABK72679.1 - 1.5e-14 54.5 7.8 2.6e-14 53.7 6.6 2.1 1 1 0 1 1 1 1 FCD domain Fer2 PF00111.27 ABK72679.1 - 1.3e-11 44.3 0.6 2.9e-11 43.2 0.6 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain KR PF08659.10 ABK72679.1 - 0.00013 22.0 1.1 0.00027 20.9 1.1 1.5 1 0 0 1 1 1 1 KR domain SIP PF04954.13 ABK72679.1 - 0.0061 17.1 0.1 0.65 10.5 0.0 3.0 2 0 0 2 2 2 1 Siderophore-interacting protein NAD_binding_6 PF08030.12 ABK72679.1 - 0.0084 16.2 0.0 5 7.2 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain SnoaL_4 PF13577.6 ABK72680.1 - 0.0036 17.4 0.0 0.0047 17.0 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain Inositol_P PF00459.25 ABK72681.1 - 6.4e-57 193.1 2.1 7.7e-57 192.9 2.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family IclR PF01614.18 ABK72682.1 - 4.9e-29 100.8 0.1 1e-28 99.7 0.0 1.6 2 0 0 2 2 2 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 ABK72682.1 - 4.6e-16 58.4 0.3 1.9e-14 53.2 0.0 2.8 3 0 0 3 3 3 1 IclR helix-turn-helix domain HTH_24 PF13412.6 ABK72682.1 - 4.1e-06 26.3 0.0 9.1e-06 25.1 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 ABK72682.1 - 0.00055 19.8 0.0 0.0019 18.1 0.0 1.9 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 ABK72682.1 - 0.00063 19.6 0.0 0.0022 17.8 0.0 1.9 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.20 ABK72682.1 - 0.0057 16.5 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR PF01047.22 ABK72682.1 - 0.013 15.4 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_AsnC-type PF13404.6 ABK72682.1 - 0.052 13.4 0.4 2.1 8.3 0.1 3.1 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain Rrf2 PF02082.20 ABK72682.1 - 0.071 13.5 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator RPA_C PF08784.11 ABK72682.1 - 0.12 13.0 0.0 0.37 11.5 0.0 1.8 1 0 0 1 1 1 0 Replication protein A C terminal TetR_N PF00440.23 ABK72683.1 - 2.1e-18 65.8 0.1 5.4e-18 64.5 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_Tnp_1_2 PF13022.6 ABK72683.1 - 0.0027 17.8 0.0 0.059 13.5 0.0 2.3 1 1 0 2 2 2 1 Helix-turn-helix of insertion element transposase TetR_C_24 PF17932.1 ABK72683.1 - 0.0046 17.2 0.1 0.0072 16.6 0.1 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_33 PF13305.6 ABK72683.1 - 0.0049 17.6 0.1 0.011 16.5 0.1 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_14 PF17754.1 ABK72683.1 - 0.0061 16.5 0.7 0.015 15.2 0.6 1.8 1 1 0 1 1 1 1 MftR C-terminal domain LMF1 PF06762.14 ABK72684.1 - 1.7e-127 426.2 18.0 4.5e-67 227.1 5.2 2.1 2 0 0 2 2 2 2 Lipase maturation factor VirB8 PF04335.13 ABK72685.1 - 0.00077 19.3 4.0 0.00077 19.3 4.0 2.2 1 1 1 2 2 2 1 VirB8 protein PBP_N PF17093.5 ABK72685.1 - 0.0019 18.4 0.4 0.0066 16.7 0.1 2.0 2 0 0 2 2 2 1 Penicillin-binding protein N-terminus PepSY_TM_like_2 PF16357.5 ABK72685.1 - 0.0069 16.4 0.5 0.0069 16.4 0.5 2.1 2 1 0 2 2 2 1 Putative PepSY_TM-like Tim54 PF11711.8 ABK72685.1 - 0.042 12.6 2.5 0.055 12.2 2.5 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Nop14 PF04147.12 ABK72685.1 - 0.046 11.9 13.7 0.051 11.8 13.7 1.2 1 0 0 1 1 1 0 Nop14-like family DUF4637 PF15470.6 ABK72685.1 - 4.1 7.1 17.4 0.56 9.9 12.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4637) TPP_enzyme_M PF00205.22 ABK72686.1 - 8.1e-38 129.2 1.8 8.4e-37 126.0 0.4 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 ABK72686.1 - 6.1e-37 126.8 3.9 4.3e-36 124.0 0.7 3.3 4 0 0 4 4 4 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.18 ABK72686.1 - 1.1e-32 113.0 1.2 3.2e-32 111.5 0.4 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain CO_dh PF02552.16 ABK72686.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Mem_trans PF03547.18 ABK72687.1 - 0.042 12.2 1.0 0.056 11.8 1.0 1.1 1 0 0 1 1 1 0 Membrane transport protein 7TMR-DISM_7TM PF07695.11 ABK72687.1 - 0.2 11.5 8.5 1.2 9.0 8.4 1.9 1 1 1 2 2 2 0 7TM diverse intracellular signalling TctB PF07331.11 ABK72687.1 - 0.98 9.7 8.5 4.6 7.5 8.7 2.0 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF4131 PF13567.6 ABK72687.1 - 10 5.8 9.6 1.1e+02 2.4 9.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) ECH_1 PF00378.20 ABK72688.1 - 9.3e-26 90.6 0.0 1.2e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK72688.1 - 0.00023 20.8 0.0 0.00035 20.2 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase STAT6_C PF14596.6 ABK72688.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 STAT6 C-terminal HTH_20 PF12840.7 ABK72690.1 - 1.4e-08 34.6 0.0 2.6e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 ABK72690.1 - 3.7e-05 23.5 0.0 0.00011 22.0 0.0 1.8 1 1 0 1 1 1 1 Bacterial regulatory protein, arsR family DUF3562 PF12085.8 ABK72691.1 - 0.0013 18.3 0.3 0.002 17.7 0.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3562) BMC PF00936.19 ABK72692.1 - 2.9e-19 68.8 10.1 2.2e-10 40.3 1.1 2.1 2 0 0 2 2 2 2 BMC domain p450 PF00067.22 ABK72693.1 - 1.2e-20 73.8 0.0 1.2e-16 60.6 0.0 3.1 1 1 0 1 1 1 1 Cytochrome P450 Beta-lactamase PF00144.24 ABK72694.1 - 8.5e-64 215.9 5.6 1.2e-63 215.4 5.6 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 ABK72694.1 - 4.7e-12 46.3 0.0 8.5e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Beta-lactamase2 PF13354.6 ABK72694.1 - 0.023 14.3 0.0 2.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Beta-lactamase enzyme family T7SS_ESX1_EccB PF05108.13 ABK72695.1 - 2.9e-162 540.7 2.0 3.2e-162 540.5 2.0 1.0 1 0 0 1 1 1 1 Type VII secretion system ESX-1, transport TM domain B BUD22 PF09073.10 ABK72696.1 - 0.007 15.8 1.1 0.0098 15.3 1.1 1.3 1 0 0 1 1 1 1 BUD22 YrzO PF14142.6 ABK72696.1 - 0.16 11.9 0.4 0.46 10.4 0.4 1.7 1 0 0 1 1 1 0 YrzO-like protein RNA_pol_3_Rpc31 PF11705.8 ABK72696.1 - 0.46 10.7 8.9 0.84 9.9 8.9 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 OB_aCoA_assoc PF01796.17 ABK72697.1 - 1.6e-13 50.4 0.3 2.2e-13 50.0 0.3 1.2 1 0 0 1 1 1 1 DUF35 OB-fold domain, acyl-CoA-associated DUF35_N PF12172.8 ABK72697.1 - 2.1e-07 30.7 1.0 3.6e-07 29.9 1.0 1.4 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) PBP_N PF17093.5 ABK72697.1 - 0.0082 16.4 0.3 0.011 16.0 0.3 1.3 1 0 0 1 1 1 1 Penicillin-binding protein N-terminus zf-tcix PF14952.6 ABK72697.1 - 0.17 11.5 3.5 0.26 10.9 3.5 1.2 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding DUF817 PF05675.12 ABK72698.1 - 0.13 11.9 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF817) LEH PF07858.12 ABK72699.1 - 2.5e-48 163.3 0.2 2.8e-48 163.1 0.2 1.0 1 0 0 1 1 1 1 Limonene-1,2-epoxide hydrolase catalytic domain SnoaL_2 PF12680.7 ABK72699.1 - 4.4e-16 59.4 0.3 5.5e-16 59.1 0.3 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 ABK72699.1 - 2.3e-05 24.2 0.7 0.0011 18.8 0.7 2.1 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase ADH_N PF08240.12 ABK72700.1 - 8.7e-28 96.4 2.4 1.7e-27 95.5 2.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ABK72700.1 - 1.2e-18 67.3 0.4 2.2e-18 66.5 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ABK72700.1 - 9.3e-13 48.1 0.3 1.8e-12 47.2 0.3 1.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 ABK72700.1 - 9.9e-05 23.4 0.5 0.00046 21.3 0.2 2.3 1 1 1 2 2 2 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 ABK72700.1 - 0.0062 16.8 0.3 0.012 15.9 0.3 1.5 1 0 0 1 1 1 1 TrkA-N domain FAD_binding_3 PF01494.19 ABK72700.1 - 0.0086 15.4 0.1 0.013 14.7 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 ABK72700.1 - 0.033 13.8 0.1 0.064 12.9 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 ABK72700.1 - 0.043 13.1 0.2 0.42 9.8 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PA PF02225.22 ABK72700.1 - 0.045 13.8 0.7 0.095 12.7 0.7 1.7 1 0 0 1 1 1 0 PA domain UDPG_MGDP_dh_N PF03721.14 ABK72700.1 - 0.059 12.9 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 ABK72700.1 - 0.1 12.0 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PMSR PF01625.21 ABK72701.1 - 2.4e-58 196.7 0.0 2.9e-58 196.4 0.0 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase NAD_binding_2 PF03446.15 ABK72702.1 - 3.8e-38 131.1 3.5 5.2e-38 130.7 3.5 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ABK72702.1 - 3.3e-17 62.8 0.1 1.3e-16 61.0 0.0 2.0 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 ABK72702.1 - 1.2e-12 48.3 1.2 1.2e-12 48.3 1.2 2.1 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 ABK72702.1 - 1.6e-07 31.1 0.3 1.4e-06 28.0 0.1 2.1 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 ABK72702.1 - 4.3e-07 29.5 0.2 6.8e-07 28.8 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 ABK72702.1 - 1.7e-05 24.5 0.9 2.8e-05 23.8 0.9 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 ABK72702.1 - 2.2e-05 24.5 0.4 4.3e-05 23.6 0.4 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 ABK72702.1 - 8e-05 22.6 3.3 0.00017 21.5 1.4 2.0 1 1 1 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 ABK72702.1 - 0.00025 21.3 1.8 0.0031 17.8 1.8 2.3 1 1 0 1 1 1 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 ABK72702.1 - 0.00045 19.9 0.1 0.0012 18.5 0.1 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GFO_IDH_MocA PF01408.22 ABK72702.1 - 0.0016 19.2 0.7 0.0033 18.2 0.7 1.5 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_Gly3P_dh_N PF01210.23 ABK72702.1 - 0.0041 17.1 0.7 0.0067 16.4 0.7 1.5 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus adh_short PF00106.25 ABK72702.1 - 0.013 14.9 1.2 0.044 13.2 0.6 2.0 2 0 0 2 2 2 0 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 ABK72702.1 - 0.041 14.1 0.2 0.066 13.5 0.2 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ADH_zinc_N PF00107.26 ABK72702.1 - 1.1 9.3 7.6 0.67 9.9 2.2 2.5 2 1 0 2 2 2 0 Zinc-binding dehydrogenase PknH_C PF14032.6 ABK72703.1 - 1.4e-34 119.6 1.9 1.7e-34 119.3 1.9 1.1 1 0 0 1 1 1 1 PknH-like extracellular domain Amidohydro_2 PF04909.14 ABK72704.1 - 4.8e-24 85.7 4.4 6.3e-24 85.3 4.4 1.2 1 0 0 1 1 1 1 Amidohydrolase Aconitase_C PF00694.19 ABK72705.1 - 3.4e-23 82.4 0.0 1.4e-22 80.5 0.0 1.8 1 1 0 1 1 1 1 Aconitase C-terminal domain CHASE PF03924.13 ABK72705.1 - 0.01 15.8 0.0 0.024 14.6 0.0 1.6 1 1 0 1 1 1 0 CHASE domain TetR_N PF00440.23 ABK72706.1 - 1.6e-12 47.0 0.4 1.6e-12 47.0 0.4 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 ABK72706.1 - 0.0016 18.7 0.3 0.0044 17.3 0.0 1.9 2 2 1 3 3 3 1 Tetracyclin repressor-like, C-terminal domain TetR_C_27 PF17935.1 ABK72706.1 - 0.0019 18.2 0.9 0.22 11.6 0.0 2.9 2 1 1 3 3 3 1 Tetracyclin repressor-like, C-terminal domain TetR_C_36 PF18598.1 ABK72706.1 - 0.004 17.1 0.0 0.0097 15.9 0.0 1.7 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TRM PF02005.16 ABK72706.1 - 0.011 14.9 0.1 0.016 14.4 0.1 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase IclR PF01614.18 ABK72710.1 - 8.7e-35 119.4 0.0 2e-34 118.2 0.0 1.6 2 0 0 2 2 2 1 Bacterial transcriptional regulator HTH_24 PF13412.6 ABK72710.1 - 2.9e-07 30.0 0.0 7.8e-06 25.4 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 ABK72710.1 - 7.5e-07 28.8 0.0 2.2e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 ABK72710.1 - 6.8e-06 25.9 0.0 2.2e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 ABK72710.1 - 0.01 15.7 0.0 0.032 14.1 0.0 1.8 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.7 ABK72710.1 - 0.029 14.4 1.8 0.12 12.4 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain DUF4423 PF14394.6 ABK72710.1 - 0.034 13.8 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) HTH_AsnC-type PF13404.6 ABK72710.1 - 0.038 13.8 1.5 8.2 6.4 0.2 2.7 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_45 PF14947.6 ABK72710.1 - 0.059 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix RepL PF05732.11 ABK72710.1 - 0.066 12.7 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) PAS_4 PF08448.10 ABK72710.1 - 0.074 13.3 0.1 0.32 11.3 0.0 2.1 2 1 1 3 3 3 0 PAS fold sCache_3_2 PF17203.4 ABK72710.1 - 0.074 13.2 0.1 1.7 8.7 0.0 2.3 2 0 0 2 2 2 0 Single cache domain 3 MarR PF01047.22 ABK72710.1 - 0.15 12.0 0.0 0.44 10.5 0.0 1.7 1 0 0 1 1 1 0 MarR family PRIMA1 PF16101.5 ABK72711.1 - 1.6 8.8 6.2 1.6 8.8 6.2 1.1 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 GMC_oxred_C PF05199.13 ABK72712.1 - 3.4e-23 82.8 0.1 4e-23 82.5 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase dCMP_cyt_deam_1 PF00383.23 ABK72713.1 - 4.8e-10 39.2 0.0 6.1e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ABK72713.1 - 7.3e-09 35.5 0.0 8.2e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 ABK72713.1 - 0.021 15.0 0.0 0.029 14.5 0.0 1.2 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 ABK72713.1 - 0.028 14.5 0.0 0.038 14.0 0.0 1.1 1 0 0 1 1 1 0 APOBEC2 NAD2 PF18782.1 ABK72713.1 - 0.037 14.1 0.0 0.051 13.7 0.0 1.1 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 NAD1 PF18778.1 ABK72713.1 - 0.17 12.0 0.0 0.22 11.6 0.0 1.1 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 Acyl-CoA_dh_1 PF00441.24 ABK72714.1 - 1.3e-14 54.6 0.0 2.3e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF1641 PF07849.11 ABK72715.1 - 9.4e-06 25.4 4.4 3e-05 23.8 0.1 3.4 3 1 0 3 3 3 1 Protein of unknown function (DUF1641) adh_short_C2 PF13561.6 ABK72716.1 - 3.1e-53 180.7 4.0 3.6e-53 180.5 4.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK72716.1 - 4.2e-52 176.5 0.8 4.9e-52 176.2 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK72716.1 - 1.9e-08 34.4 1.6 2.5e-08 34.0 1.6 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 ABK72716.1 - 0.0016 18.4 2.2 0.0022 17.9 2.2 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 ABK72716.1 - 0.01 16.3 0.8 0.018 15.5 0.8 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_2 PF03446.15 ABK72716.1 - 0.013 15.7 0.3 0.023 14.9 0.3 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase THF_DHG_CYH_C PF02882.19 ABK72716.1 - 0.025 13.9 0.0 0.049 13.0 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 ABK72716.1 - 0.029 14.4 0.3 0.041 13.9 0.3 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 ABK72716.1 - 0.034 14.7 2.8 0.085 13.5 1.9 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 ABK72716.1 - 0.14 12.9 0.5 0.23 12.3 0.5 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold AdoHcyase_NAD PF00670.21 ABK72716.1 - 0.41 10.7 2.2 0.9 9.6 2.2 1.6 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Bac_globin PF01152.21 ABK72717.1 - 2.2e-40 137.6 0.1 2.5e-40 137.4 0.1 1.0 1 0 0 1 1 1 1 Bacterial-like globin Abhydrolase_1 PF00561.20 ABK72719.1 - 6e-18 65.4 0.5 8e-18 65.0 0.5 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ABK72719.1 - 4.2e-06 26.2 0.9 5.5e-06 25.8 0.9 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 EHN PF06441.12 ABK72719.1 - 0.12 12.7 0.0 0.35 11.3 0.0 1.7 2 0 0 2 2 2 0 Epoxide hydrolase N terminus TAT_signal PF10518.9 ABK72719.1 - 2.3 8.2 7.4 11 6.1 7.4 2.2 1 1 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence HupF_HypC PF01455.18 ABK72721.1 - 6.2e-22 77.5 0.4 7.1e-22 77.3 0.4 1.0 1 0 0 1 1 1 1 HupF/HypC family HTH_27 PF13463.6 ABK72722.1 - 3.3e-08 33.9 0.2 1.5e-07 31.8 0.1 2.0 2 0 0 2 2 2 1 Winged helix DNA-binding domain MarR_2 PF12802.7 ABK72722.1 - 4.6e-08 32.8 0.2 1e-07 31.7 0.2 1.6 1 0 0 1 1 1 1 MarR family MarR PF01047.22 ABK72722.1 - 0.00048 20.0 0.0 0.00094 19.1 0.0 1.5 1 0 0 1 1 1 1 MarR family Fe_dep_repress PF01325.19 ABK72722.1 - 0.017 15.3 0.2 0.032 14.4 0.2 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_IclR PF09339.10 ABK72722.1 - 0.034 13.9 0.2 0.09 12.6 0.2 1.7 1 1 0 1 1 1 0 IclR helix-turn-helix domain Rio2_N PF09202.11 ABK72722.1 - 0.037 14.3 0.0 0.071 13.3 0.0 1.4 1 0 0 1 1 1 0 Rio2, N-terminal MarR_2 PF12802.7 ABK72723.1 - 2e-11 43.6 0.3 3.6e-11 42.8 0.3 1.4 1 0 0 1 1 1 1 MarR family MarR PF01047.22 ABK72723.1 - 3.4e-09 36.5 0.0 5.3e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 ABK72723.1 - 0.0051 17.3 0.1 0.0077 16.7 0.1 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain HxlR PF01638.17 ABK72723.1 - 0.0059 16.4 0.0 0.0092 15.8 0.0 1.3 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_24 PF13412.6 ABK72723.1 - 0.098 12.2 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_34 PF13601.6 ABK72723.1 - 0.13 12.4 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain WXG100 PF06013.12 ABK72724.1 - 6.4e-16 58.4 10.6 7.2e-16 58.2 10.6 1.0 1 0 0 1 1 1 1 Proteins of 100 residues with WXG FTO_CTD PF12934.7 ABK72724.1 - 0.0056 16.5 1.8 0.0076 16.0 1.8 1.1 1 0 0 1 1 1 1 FTO C-terminal domain Sensor PF13796.6 ABK72725.1 - 0.39 10.8 6.2 0.099 12.7 2.5 1.9 2 0 0 2 2 2 0 Putative sensor PRiA4_ORF3 PF07929.11 ABK72726.1 - 2.1e-51 174.1 0.0 2.5e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein TetR_N PF00440.23 ABK72727.1 - 6.7e-19 67.4 0.2 1.7e-18 66.2 0.2 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family DUF429 PF04250.13 ABK72727.1 - 0.03 14.1 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF429) HTH_Tnp_1_2 PF13022.6 ABK72727.1 - 0.058 13.6 0.0 0.093 12.9 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase Ice_nucleation PF00818.17 ABK72727.1 - 0.15 12.2 1.7 0.5 10.5 0.4 2.3 2 0 0 2 2 2 0 Ice nucleation protein repeat Aldedh PF00171.22 ABK72728.1 - 1.7e-158 528.0 6.9 2e-158 527.7 6.9 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RTC_insert PF05189.13 ABK72729.1 - 0.08 13.5 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 RNA 3'-terminal phosphate cyclase (RTC), insert domain DUF4222 PF13973.6 ABK72729.1 - 0.19 11.3 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4222) HTH_Tnp_1 PF01527.20 ABK72730.1 - 0.00079 19.7 0.6 0.0018 18.5 0.6 1.6 1 1 0 1 1 1 1 Transposase DUF4407 PF14362.6 ABK72730.1 - 0.0081 15.5 2.1 0.0094 15.3 2.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Paramyx_P_V_C PF03210.13 ABK72730.1 - 0.096 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal Ribosomal_L11 PF00298.19 ABK72730.1 - 0.11 13.0 0.2 0.16 12.5 0.2 1.3 1 0 0 1 1 1 0 Ribosomal protein L11, RNA binding domain SlyX PF04102.12 ABK72730.1 - 0.12 13.0 1.1 0.28 11.8 1.1 1.7 1 1 0 1 1 1 0 SlyX DUF1192 PF06698.11 ABK72730.1 - 1.7 8.7 5.2 1.6 8.8 3.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Amidohydro_1 PF01979.20 ABK72732.1 - 5.7e-25 88.4 3.5 7.7e-25 87.9 3.5 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ABK72732.1 - 8.3e-07 28.8 15.4 0.0019 17.7 8.4 2.2 2 0 0 2 2 2 2 Amidohydrolase family Acyl-CoA_dh_1 PF00441.24 ABK72733.1 - 1e-37 129.7 1.9 1.5e-37 129.1 1.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK72733.1 - 3.8e-22 78.3 0.0 7.4e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ABK72733.1 - 2.3e-14 53.8 3.6 4.1e-14 53.0 3.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK72733.1 - 1.9e-08 34.9 0.1 3.5e-08 34.1 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 ABK72733.1 - 0.067 12.8 0.1 0.31 10.7 0.1 2.0 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal DUF4746 PF15928.5 ABK72733.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) LGFP PF08310.11 ABK72735.1 - 2.5e-54 181.6 25.3 5.6e-12 46.0 0.3 7.0 7 0 0 7 7 7 6 LGFP repeat DsbC_N PF10411.9 ABK72735.1 - 0.062 12.8 0.8 5 6.6 0.1 2.4 2 0 0 2 2 2 0 Disulfide bond isomerase protein N-terminus DUF4381 PF14316.6 ABK72735.1 - 1.2 9.4 5.4 0.26 11.5 1.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) p450 PF00067.22 ABK72736.1 - 1.2e-25 90.2 0.0 3.3e-23 82.2 0.0 2.9 2 1 0 2 2 2 1 Cytochrome P450 MR_MLE_C PF13378.6 ABK72737.1 - 7.7e-43 146.6 0.0 1.3e-42 145.8 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 ABK72737.1 - 4.3e-21 75.3 0.1 8.4e-21 74.4 0.1 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MdcG PF10620.9 ABK72737.1 - 0.075 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG p450 PF00067.22 ABK72738.1 - 1.6e-13 50.2 0.0 2.1e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SIP PF04954.13 ABK72739.1 - 3e-27 95.5 0.1 5.7e-27 94.6 0.1 1.5 1 0 0 1 1 1 1 Siderophore-interacting protein FAD_binding_9 PF08021.11 ABK72739.1 - 5.1e-11 42.8 0.2 3.5e-06 27.2 0.1 2.4 1 1 1 2 2 2 2 Siderophore-interacting FAD-binding domain 4HBT PF03061.22 ABK72740.1 - 1.4e-13 51.0 1.1 1.8e-13 50.7 1.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 ABK72740.1 - 7e-07 29.7 1.7 8.2e-07 29.5 1.7 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.6 ABK72740.1 - 0.00021 21.5 0.1 0.00024 21.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) Beta-lactamase2 PF13354.6 ABK72741.1 - 1.2e-24 87.1 0.0 1.9e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase enzyme family ORF_12_N PF18042.1 ABK72741.1 - 2.6e-15 56.6 0.1 5.2e-15 55.6 0.1 1.5 1 0 0 1 1 1 1 ORF 12 gene product N-terminal Peptidase_S11 PF00768.20 ABK72741.1 - 3e-06 26.8 0.0 4.9e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase PF00144.24 ABK72741.1 - 0.0034 16.7 0.5 0.014 14.7 0.1 1.9 2 0 0 2 2 2 1 Beta-lactamase AMP-binding PF00501.28 ABK72742.1 - 1.6e-93 313.6 0.0 2e-93 313.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Thiolase_N PF00108.23 ABK72743.1 - 5.8e-70 235.6 0.4 8.3e-70 235.1 0.4 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ABK72743.1 - 5.2e-38 129.5 0.3 1e-37 128.5 0.3 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ABK72743.1 - 2.6e-07 30.5 0.4 6.9e-07 29.1 0.4 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 ABK72743.1 - 0.013 15.4 1.8 0.32 10.9 0.3 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HNH_3 PF13392.6 ABK72743.1 - 0.19 11.5 0.0 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 HNH endonuclease Pyr_redox_2 PF07992.14 ABK72744.1 - 1.9e-20 73.3 0.1 2.9e-20 72.7 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_11 PF08241.12 ABK72744.1 - 2.1e-18 66.8 0.0 4.6e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABK72744.1 - 1.7e-17 63.9 0.0 3.9e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABK72744.1 - 2.3e-13 50.3 0.0 4.3e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABK72744.1 - 4.7e-13 49.2 0.0 8.2e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK72744.1 - 3.5e-12 46.9 0.0 8.7e-12 45.7 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain TPMT PF05724.11 ABK72744.1 - 3.2e-11 43.3 0.0 5e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 ABK72744.1 - 3.3e-09 36.5 0.0 7.6e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 ABK72744.1 - 7.5e-07 28.7 0.0 1.1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB FAD_binding_2 PF00890.24 ABK72744.1 - 2.9e-06 26.6 9.3 3e-05 23.3 3.7 2.7 2 1 1 3 3 3 2 FAD binding domain Ubie_methyltran PF01209.18 ABK72744.1 - 4.8e-06 26.1 0.0 7.9e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NAD_binding_8 PF13450.6 ABK72744.1 - 4.1e-05 23.7 1.1 0.00017 21.8 1.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ABK72744.1 - 5.1e-05 22.1 0.2 9.1e-05 21.3 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Methyltransf_15 PF09445.10 ABK72744.1 - 0.00021 20.9 0.0 0.0003 20.4 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Pyr_redox_3 PF13738.6 ABK72744.1 - 0.00082 18.7 0.0 0.023 14.0 0.3 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ABK72744.1 - 0.0021 17.7 11.6 0.0095 15.6 11.6 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ABK72744.1 - 0.0022 17.1 0.5 0.0058 15.7 0.5 1.7 1 0 0 1 1 1 1 Lycopene cyclase protein CheR PF01739.18 ABK72744.1 - 0.0036 16.8 0.0 0.17 11.3 0.0 2.2 1 1 0 2 2 2 1 CheR methyltransferase, SAM binding domain GIDA PF01134.22 ABK72744.1 - 0.0039 16.3 4.3 0.066 12.3 1.3 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A Methyltransf_18 PF12847.7 ABK72744.1 - 0.0061 16.5 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FAD_binding_3 PF01494.19 ABK72744.1 - 0.0066 15.7 0.4 0.011 15.0 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 ABK72744.1 - 0.011 15.2 2.3 0.016 14.5 2.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase CbiA PF01656.23 ABK72744.1 - 0.011 15.8 0.0 0.16 12.0 0.0 2.1 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain NodS PF05401.11 ABK72744.1 - 0.012 15.2 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Thi4 PF01946.17 ABK72744.1 - 0.025 13.8 0.2 0.08 12.2 0.1 1.8 2 0 0 2 2 2 0 Thi4 family Pox_MCEL PF03291.16 ABK72744.1 - 0.031 13.4 0.0 0.22 10.6 0.0 1.9 1 1 0 1 1 1 0 mRNA capping enzyme Trp_halogenase PF04820.14 ABK72744.1 - 0.051 12.4 0.5 0.078 11.8 0.5 1.2 1 0 0 1 1 1 0 Tryptophan halogenase MetW PF07021.12 ABK72744.1 - 0.091 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Pyr_redox PF00070.27 ABK72744.1 - 0.2 12.2 0.2 0.84 10.2 0.1 2.1 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF2173 PF09941.9 ABK72744.1 - 0.21 11.9 0.6 2.4 8.5 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2173) Fer4_13 PF13370.6 ABK72745.1 - 6e-13 49.1 0.4 6.9e-13 48.9 0.4 1.1 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 ABK72745.1 - 2.2e-11 44.3 1.4 6e-11 42.9 1.4 1.6 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_19 PF06902.11 ABK72745.1 - 9e-06 25.7 0.1 9.5e-06 25.6 0.1 1.1 1 0 0 1 1 1 1 Divergent 4Fe-4S mono-cluster Cutinase PF01083.22 ABK72746.1 - 1.3e-52 178.3 0.1 1.6e-52 178.1 0.1 1.1 1 0 0 1 1 1 1 Cutinase SP2 PF03014.14 ABK72746.1 - 0.068 11.6 0.0 0.08 11.3 0.0 1.1 1 0 0 1 1 1 0 Structural protein 2 Peripla_BP_6 PF13458.6 ABK72747.1 - 2.3e-38 132.7 8.1 2.8e-38 132.5 8.1 1.1 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 ABK72747.1 - 1.2e-11 44.4 0.0 1.6e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_5 PF13433.6 ABK72747.1 - 1.5e-05 24.2 0.1 2.9e-05 23.2 0.0 1.5 2 0 0 2 2 2 1 Periplasmic binding protein domain LppC PF04348.13 ABK72747.1 - 0.1 11.4 0.2 0.13 11.1 0.2 1.1 1 0 0 1 1 1 0 LppC putative lipoprotein CoA_trans PF01144.23 ABK72748.1 - 2.6e-68 229.7 0.3 3e-68 229.5 0.3 1.0 1 0 0 1 1 1 1 Coenzyme A transferase UvdE PF03851.14 ABK72748.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 UV-endonuclease UvdE DUF4185 PF13810.6 ABK72749.1 - 6.2e-56 189.9 0.1 7.2e-56 189.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) DNA_gyraseB PF00204.25 ABK72750.1 - 5.6e-64 214.8 1.1 5.6e-64 214.8 1.1 1.7 2 0 0 2 2 2 1 DNA gyrase B DNA_gyraseB_C PF00986.21 ABK72750.1 - 1.4e-26 92.5 0.0 3e-26 91.4 0.0 1.6 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 ABK72750.1 - 1.5e-22 80.2 0.0 3.7e-22 78.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 ABK72750.1 - 1.2e-16 60.8 0.0 2.7e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 Toprim domain HATPase_c_3 PF13589.6 ABK72750.1 - 0.0066 16.3 0.1 0.013 15.3 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase adh_short PF00106.25 ABK72751.1 - 1.6e-47 161.5 0.0 2.2e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK72751.1 - 1.7e-33 116.2 0.0 2.2e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK72751.1 - 5.2e-15 55.8 0.1 8.9e-15 55.1 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ABK72751.1 - 5.7e-06 26.4 0.1 9.1e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 ABK72751.1 - 1.2e-05 24.6 0.1 1.5e-05 24.3 0.1 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 ABK72751.1 - 0.00023 20.7 0.2 0.00038 20.0 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ABK72751.1 - 0.015 14.3 0.1 0.023 13.7 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family AP_endonuc_2 PF01261.24 ABK72752.1 - 1.3e-15 57.4 0.3 1.8e-15 56.9 0.3 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel FtsK_SpoIIIE PF01580.18 ABK72753.1 - 6.5e-95 317.1 0.1 5.1e-52 176.6 0.0 5.1 4 1 1 5 5 5 4 FtsK/SpoIIIE family AAA_22 PF13401.6 ABK72753.1 - 3.6e-12 46.7 0.0 0.0016 18.8 0.0 3.9 4 0 0 4 4 3 3 AAA domain NACHT PF05729.12 ABK72753.1 - 8.2e-10 38.8 0.2 0.0043 17.0 0.0 4.8 4 2 0 4 4 4 3 NACHT domain AAA_16 PF13191.6 ABK72753.1 - 1.4e-08 35.3 6.9 0.031 14.6 0.1 4.7 3 2 0 3 3 3 3 AAA ATPase domain AAA_19 PF13245.6 ABK72753.1 - 7.5e-08 32.8 0.0 0.2 12.0 0.0 3.5 3 0 0 3 3 3 2 AAA domain DUF87 PF01935.17 ABK72753.1 - 8.1e-08 32.6 0.8 0.019 15.1 0.2 2.6 3 0 0 3 3 2 2 Helicase HerA, central domain ABC_tran PF00005.27 ABK72753.1 - 9e-07 29.5 0.1 0.0051 17.3 0.0 3.4 3 0 0 3 3 3 1 ABC transporter RNA_helicase PF00910.22 ABK72753.1 - 4.7e-06 26.9 0.0 0.26 11.7 0.0 3.4 3 0 0 3 3 3 2 RNA helicase AAA_33 PF13671.6 ABK72753.1 - 5.3e-06 26.6 0.1 2.9 8.1 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 ABK72753.1 - 6.1e-06 25.9 0.8 1.4 8.7 0.0 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_24 PF13479.6 ABK72753.1 - 4.2e-05 23.4 0.0 0.54 10.0 0.0 3.5 3 1 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 ABK72753.1 - 5.1e-05 23.3 0.0 1.7 8.8 0.0 3.5 3 0 0 3 3 3 2 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 ABK72753.1 - 6.9e-05 22.7 0.1 0.021 14.6 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 ABK72753.1 - 0.00017 21.4 0.6 0.8 9.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain TrwB_AAD_bind PF10412.9 ABK72753.1 - 0.00036 19.6 0.2 2.2 7.1 0.0 3.2 3 0 0 3 3 3 2 Type IV secretion-system coupling protein DNA-binding domain AAA_23 PF13476.6 ABK72753.1 - 0.00078 20.0 0.0 0.36 11.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 ABK72753.1 - 0.00091 19.5 0.8 3.7 7.8 0.0 3.9 4 0 0 4 4 4 1 AAA domain AAA_10 PF12846.7 ABK72753.1 - 0.0022 17.0 0.0 21 3.9 0.0 3.9 4 0 0 4 4 4 0 AAA-like domain AAA_18 PF13238.6 ABK72753.1 - 0.0027 18.2 0.1 3.8 8.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain DUF815 PF05673.13 ABK72753.1 - 0.01 15.0 0.2 1.2 8.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF815) Roc PF08477.13 ABK72753.1 - 0.013 15.7 0.0 1.9 8.7 0.0 3.0 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase T2SSE PF00437.20 ABK72753.1 - 0.031 13.3 0.0 21 4.1 0.0 3.1 3 0 0 3 3 3 0 Type II/IV secretion system protein Pox_A32 PF04665.12 ABK72753.1 - 0.04 13.4 0.1 9.2 5.6 0.1 2.8 3 0 0 3 3 3 0 Poxvirus A32 protein Mg_chelatase PF01078.21 ABK72753.1 - 0.048 13.0 0.2 12 5.2 0.0 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI CLP1_P PF16575.5 ABK72753.1 - 0.049 13.4 0.1 7.8 6.2 0.0 3.3 4 0 0 4 4 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_5 PF07728.14 ABK72753.1 - 0.055 13.5 0.1 2.5 8.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) KTI12 PF08433.10 ABK72753.1 - 0.057 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA PF00004.29 ABK72753.1 - 0.061 13.8 0.0 7 7.1 0.0 3.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 ABK72753.1 - 0.062 12.6 1.4 17 4.6 0.0 3.6 4 0 0 4 4 4 0 Zeta toxin Adeno_IVa2 PF02456.15 ABK72753.1 - 0.099 11.4 0.0 8.9 5.0 0.1 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein Rad17 PF03215.15 ABK72753.1 - 0.29 11.0 0.0 0.65 9.9 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain MeaB PF03308.16 ABK72753.1 - 0.34 9.9 1.4 6.9 5.6 0.0 2.8 3 1 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB BPD_transp_1 PF00528.22 ABK72754.1 - 2.1e-35 122.2 12.9 2.1e-35 122.2 12.9 2.2 2 1 1 3 3 3 1 Binding-protein-dependent transport system inner membrane component Ribosomal_L31 PF01197.18 ABK72755.1 - 2.6e-30 104.5 0.0 2.9e-30 104.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L31 DUF4992 PF16383.5 ABK72755.1 - 0.16 11.5 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function AIG2_2 PF13772.6 ABK72756.1 - 4.7e-24 84.6 0.0 5.9e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 AIG2-like family GGACT PF06094.12 ABK72756.1 - 1.1e-08 35.7 0.0 1.4e-08 35.3 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Glyoxalase PF00903.25 ABK72758.1 - 1.7e-10 41.1 0.0 8.6e-06 26.0 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ABK72758.1 - 0.0022 18.8 0.0 0.0054 17.5 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 ABK72758.1 - 0.032 14.3 0.1 0.061 13.4 0.1 1.6 1 1 1 2 2 2 0 Glyoxalase-like domain Glyoxalase_4 PF13669.6 ABK72758.1 - 0.058 13.7 0.0 0.088 13.1 0.0 1.4 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily LGT PF01790.18 ABK72759.1 - 8e-62 208.6 11.0 9.9e-62 208.3 11.0 1.1 1 0 0 1 1 1 1 Prolipoprotein diacylglyceryl transferase PDH_E1_M PF17831.1 ABK72760.1 - 1.8e-112 374.5 0.1 4e-112 373.4 0.1 1.6 2 0 0 2 2 2 1 Pyruvate dehydrogenase E1 component middle domain Transketolase_N PF00456.21 ABK72760.1 - 2.5e-15 56.3 0.0 5.3e-11 42.1 0.0 2.3 2 0 0 2 2 2 2 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 ABK72760.1 - 0.01 15.7 0.1 0.035 14.0 0.0 1.9 2 0 0 2 2 2 0 Transketolase, C-terminal domain ABM PF03992.16 ABK72761.1 - 1.3e-14 54.1 0.8 1.7e-14 53.7 0.8 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Asp_Glu_race PF01177.22 ABK72762.1 - 3.2e-30 105.6 0.0 4e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Allantoicase PF03561.15 ABK72763.1 - 3.8e-87 289.6 0.0 3.5e-48 163.2 0.1 2.4 2 1 0 2 2 2 2 Allantoicase repeat Band_7 PF01145.25 ABK72764.1 - 2e-24 86.6 1.1 2e-24 86.6 1.1 4.4 2 1 1 3 3 3 1 SPFH domain / Band 7 family Flot PF15975.5 ABK72764.1 - 9.4e-05 22.6 7.2 9.4e-05 22.6 7.2 6.3 1 1 5 6 6 6 1 Flotillin Band_7_1 PF13421.6 ABK72764.1 - 0.011 15.5 1.1 0.019 14.6 0.1 1.8 2 0 0 2 2 2 0 SPFH domain-Band 7 family EOS1 PF12326.8 ABK72764.1 - 0.77 9.7 1.7 1.7 8.5 1.6 1.8 1 1 0 1 1 1 0 N-glycosylation protein Hydrolase_6 PF13344.6 ABK72765.1 - 3.6e-24 84.8 0.0 6.3e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ABK72765.1 - 2.8e-23 81.8 0.0 8.1e-23 80.3 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 ABK72765.1 - 3.4e-08 33.8 0.0 2.8e-07 30.8 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ABK72765.1 - 1.2e-07 32.2 0.3 3.9e-06 27.3 0.3 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Arg_repressor_C PF02863.18 ABK72765.1 - 0.096 12.5 0.4 0.98 9.3 0.6 2.4 2 0 0 2 2 2 0 Arginine repressor, C-terminal domain Sulfate_transp PF00916.20 ABK72766.1 - 3e-47 161.2 31.2 4.1e-27 94.9 4.5 2.1 1 1 1 2 2 2 2 Sulfate permease family STAS PF01740.21 ABK72766.1 - 2.2e-08 33.8 0.0 4e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 ABK72766.1 - 2.6e-05 24.5 0.3 0.0001 22.6 0.0 2.2 2 0 0 2 2 2 1 STAS domain MFS_MOT1 PF16983.5 ABK72766.1 - 3.7e-05 24.1 50.0 9.7e-05 22.7 6.8 4.1 4 0 0 4 4 4 3 Molybdate transporter of MFS superfamily Polyketide_cyc2 PF10604.9 ABK72767.1 - 6.8e-13 49.1 0.8 6.8e-13 49.1 0.8 2.2 3 0 0 3 3 3 1 Polyketide cyclase / dehydrase and lipid transport TetR_N PF00440.23 ABK72767.1 - 2e-12 46.7 0.2 5.2e-12 45.4 0.2 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family AHSA1 PF08327.11 ABK72767.1 - 2.6e-07 30.9 0.2 3.9e-07 30.3 0.2 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein TetR_C_33 PF13305.6 ABK72767.1 - 1.5 9.6 7.8 0.14 12.9 2.2 2.2 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain NMT1 PF09084.11 ABK72768.1 - 3.3e-22 79.5 0.1 5.2e-22 78.8 0.1 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 ABK72768.1 - 5.8e-15 55.7 0.4 5.2e-14 52.6 0.4 2.0 1 1 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 ABK72768.1 - 3.5e-06 26.8 0.5 0.017 14.7 0.2 2.3 1 1 1 2 2 2 2 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 ABK72768.1 - 0.00029 20.3 0.1 0.0037 16.7 0.0 2.2 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_3 PF16868.5 ABK72768.1 - 0.043 13.2 0.1 0.088 12.2 0.1 1.5 1 1 0 1 1 1 0 NMT1-like family LPAM_2 PF13627.6 ABK72768.1 - 1.3 9.0 3.8 2.1 8.3 3.8 1.3 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site Bac_luciferase PF00296.20 ABK72769.1 - 5.9e-53 180.3 0.2 6.9e-53 180.1 0.2 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Tautomerase_3 PF14832.6 ABK72770.1 - 3.2e-15 56.5 0.0 4e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.21 ABK72770.1 - 5.8e-12 45.4 0.1 3.5e-07 30.0 0.0 2.1 2 0 0 2 2 2 2 Tautomerase enzyme Tautomerase_2 PF14552.6 ABK72770.1 - 0.005 16.9 0.0 0.055 13.6 0.0 2.1 1 1 1 2 2 2 1 Tautomerase enzyme NTP_transferase PF00483.23 ABK72771.1 - 1.9e-64 217.6 0.0 2.4e-64 217.3 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 ABK72771.1 - 4.2e-12 46.7 0.0 5.1e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 ABK72771.1 - 0.0063 16.3 0.0 0.0093 15.7 0.0 1.2 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase adh_short PF00106.25 ABK72772.1 - 1.7e-52 177.7 0.7 2.3e-52 177.3 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK72772.1 - 5.9e-41 140.5 6.2 7.2e-41 140.3 6.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK72772.1 - 3.4e-13 49.9 1.1 5.5e-13 49.2 1.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK72772.1 - 6.2e-10 38.9 0.8 6.1e-08 32.4 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 ABK72772.1 - 0.014 15.6 0.2 0.03 14.6 0.1 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Pilus_CpaD PF09476.10 ABK72772.1 - 0.017 14.9 0.6 0.036 13.8 0.3 1.7 1 1 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) ImmE5 PF11480.8 ABK72772.1 - 0.11 13.0 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 Colicin-E5 Imm protein zf-CDGSH PF09360.10 ABK72773.1 - 2.2e-15 56.6 0.5 2.8e-15 56.2 0.5 1.1 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type Apolipoprotein PF01442.18 ABK72774.1 - 0.0015 18.4 6.5 0.0092 15.9 6.5 2.0 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain ApoO PF09769.9 ABK72774.1 - 0.071 13.1 1.6 0.2 11.6 1.1 2.0 2 0 0 2 2 2 0 Apolipoprotein O Mitofilin PF09731.9 ABK72774.1 - 0.24 10.2 16.5 0.32 9.8 16.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Prominin PF05478.11 ABK72774.1 - 0.57 8.1 1.7 1 7.2 1.7 1.3 1 0 0 1 1 1 0 Prominin Baculo_PEP_C PF04513.12 ABK72774.1 - 0.84 9.7 3.0 17 5.4 0.1 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 ABK72774.1 - 1.3 9.1 12.9 3.4 7.8 10.3 2.3 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Ppx-GppA PF02541.16 ABK72775.1 - 1.7e-76 257.4 0.1 1.9e-76 257.2 0.1 1.0 1 0 0 1 1 1 1 Ppx/GppA phosphatase family FtsA PF14450.6 ABK72775.1 - 0.11 13.0 0.2 4.6 7.7 0.1 2.5 2 1 0 2 2 2 0 Cell division protein FtsA Ring_hydroxyl_B PF00866.18 ABK72776.1 - 6.5e-45 152.8 1.0 7.4e-45 152.6 1.0 1.0 1 0 0 1 1 1 1 Ring hydroxylating beta subunit SnoaL_4 PF13577.6 ABK72776.1 - 0.00016 21.8 0.0 0.00026 21.1 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 ABK72776.1 - 0.13 12.7 0.3 0.32 11.4 0.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 ABK72776.1 - 0.13 12.9 1.0 0.3 11.8 1.0 1.8 1 1 0 1 1 1 0 SnoaL-like domain UvrA_DNA-bind PF17755.1 ABK72777.1 - 2.6e-17 63.2 0.0 8.9e-17 61.4 0.0 1.9 2 0 0 2 2 2 1 UvrA DNA-binding domain ABC_tran PF00005.27 ABK72777.1 - 2.1e-15 57.4 0.0 8.3e-09 36.1 0.0 4.3 3 1 0 3 3 3 2 ABC transporter AAA_29 PF13555.6 ABK72777.1 - 4.9e-08 32.6 0.1 0.0018 18.0 0.0 2.9 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_16 PF13191.6 ABK72777.1 - 1.8e-07 31.7 1.3 0.11 12.9 0.0 3.9 4 0 0 4 4 4 2 AAA ATPase domain SMC_N PF02463.19 ABK72777.1 - 1.4e-06 27.9 0.0 1 8.7 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain DnaJ_CXXCXGXG PF00684.19 ABK72777.1 - 1.7e-06 28.3 1.1 0.057 13.8 0.2 3.4 3 0 0 3 3 3 1 DnaJ central domain AAA_21 PF13304.6 ABK72777.1 - 5.4e-06 26.4 9.4 0.0082 16.0 0.0 3.9 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 ABK72777.1 - 2.6e-05 23.9 0.0 0.056 13.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain Anti-TRAP PF15777.5 ABK72777.1 - 0.00022 21.1 0.8 0.25 11.4 0.1 3.5 3 0 0 3 3 3 1 Tryptophan RNA-binding attenuator protein inhibitory protein NACHT PF05729.12 ABK72777.1 - 0.00023 21.1 0.0 0.074 13.0 0.1 2.4 2 0 0 2 2 2 1 NACHT domain RsgA_GTPase PF03193.16 ABK72777.1 - 0.0015 18.5 0.0 1.5 8.7 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase APS_kinase PF01583.20 ABK72777.1 - 0.0019 18.1 0.2 1.7 8.5 0.0 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_33 PF13671.6 ABK72777.1 - 0.002 18.3 0.0 0.96 9.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ABK72777.1 - 0.0029 17.9 0.6 1.9 8.8 0.0 3.5 4 0 0 4 4 4 1 AAA domain NB-ARC PF00931.22 ABK72777.1 - 0.0098 15.1 0.1 1.2 8.2 0.1 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_15 PF13175.6 ABK72777.1 - 0.012 15.3 0.0 1.2 8.7 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain MeaB PF03308.16 ABK72777.1 - 0.014 14.4 0.3 0.95 8.4 0.2 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase PF06745.13 ABK72777.1 - 0.019 14.3 0.0 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 KaiC MMR_HSR1 PF01926.23 ABK72777.1 - 0.02 14.9 0.2 7.2 6.7 0.0 3.4 3 0 0 3 3 3 0 50S ribosome-binding GTPase cobW PF02492.19 ABK72777.1 - 0.031 13.9 0.3 0.38 10.3 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 ABK72777.1 - 0.059 13.9 3.7 1.8 9.2 0.2 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 ABK72777.1 - 0.064 13.2 1.0 0.23 11.4 0.2 2.2 3 0 0 3 3 2 0 NTPase Viral_helicase1 PF01443.18 ABK72777.1 - 0.065 13.0 0.5 0.55 9.9 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 ABK72777.1 - 0.093 12.4 0.6 7.6 6.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain DUF4350 PF14258.6 ABK72777.1 - 0.1 13.1 0.4 2.8 8.4 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4350) DUF2075 PF09848.9 ABK72777.1 - 0.19 10.9 0.3 3 7.0 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PRK PF00485.18 ABK72777.1 - 0.78 9.4 2.3 5.5 6.7 0.0 2.8 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family GerE PF00196.19 ABK72778.1 - 2.4e-14 52.6 0.0 4.2e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 ABK72778.1 - 1.6e-05 24.5 1.2 3.7e-05 23.3 0.2 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 AAA_30 PF13604.6 ABK72778.1 - 0.0081 15.9 0.8 0.0081 15.9 0.8 3.0 3 1 1 4 4 4 1 AAA domain T2SSE PF00437.20 ABK72778.1 - 0.01 14.9 0.0 0.021 13.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 ABK72778.1 - 0.033 13.9 0.1 0.07 12.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Thymidylate_kin PF02223.17 ABK72778.1 - 0.038 13.7 0.0 0.073 12.7 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase Zeta_toxin PF06414.12 ABK72778.1 - 0.051 12.9 0.1 0.11 11.7 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin Sigma70_r4 PF04545.16 ABK72778.1 - 0.052 13.1 0.4 0.2 11.2 0.4 2.1 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_38 PF13936.6 ABK72778.1 - 0.1 12.3 0.0 0.43 10.4 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain AAA_19 PF13245.6 ABK72778.1 - 0.12 12.7 0.5 0.77 10.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain Trans_reg_C PF00486.28 ABK72778.1 - 0.13 12.4 0.0 0.45 10.6 0.0 2.0 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal AAA_22 PF13401.6 ABK72778.1 - 0.23 11.7 3.2 8.1 6.7 0.3 2.8 1 1 1 2 2 2 0 AAA domain WXG100 PF06013.12 ABK72779.1 - 1.7e-06 28.2 2.3 1.7e-06 28.2 2.3 2.1 2 0 0 2 2 2 1 Proteins of 100 residues with WXG Snapin_Pallidin PF14712.6 ABK72779.1 - 0.012 16.0 0.0 0.25 11.8 0.0 2.5 2 1 0 2 2 2 0 Snapin/Pallidin Baculo_PEP_C PF04513.12 ABK72779.1 - 0.08 13.0 0.5 0.31 11.1 0.0 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lant_dehydr_C PF14028.6 ABK72779.1 - 0.11 12.0 2.8 0.12 11.9 2.4 1.4 1 1 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term ABC_tran PF00005.27 ABK72780.1 - 1.2e-36 126.2 0.0 1.8e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter TOBE_3 PF12857.7 ABK72780.1 - 1.4e-11 44.2 0.3 3.2e-11 43.0 0.3 1.7 1 0 0 1 1 1 1 TOBE-like domain TOBE PF03459.17 ABK72780.1 - 2.9e-10 40.3 0.6 7.3e-10 39.0 0.6 1.7 1 0 0 1 1 1 1 TOBE domain AAA_21 PF13304.6 ABK72780.1 - 6.4e-10 39.3 0.5 8.5e-05 22.5 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system TOBE_2 PF08402.10 ABK72780.1 - 2.1e-06 27.8 1.8 8.2e-06 25.9 0.6 2.4 2 0 0 2 2 2 1 TOBE domain SMC_N PF02463.19 ABK72780.1 - 2.1e-06 27.3 0.0 0.038 13.4 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ABK72780.1 - 1.2e-05 25.0 0.1 2.3e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 ABK72780.1 - 2.7e-05 24.8 0.0 4.3e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ABK72780.1 - 0.00015 22.0 0.2 0.0014 18.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ABK72780.1 - 0.00026 21.4 0.4 0.00068 20.1 0.4 1.8 1 1 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.9 ABK72780.1 - 0.00032 19.6 0.2 0.94 8.2 0.0 3.1 2 1 0 2 2 2 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 ABK72780.1 - 0.00072 19.5 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 ABK72780.1 - 0.0023 18.3 0.0 0.021 15.2 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 ABK72780.1 - 0.01 15.3 0.0 0.26 10.7 0.0 2.1 2 0 0 2 2 2 1 Bacterial TniB protein AAA_27 PF13514.6 ABK72780.1 - 0.01 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ABK72780.1 - 0.011 15.5 0.2 0.028 14.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ABK72780.1 - 0.011 15.3 0.5 0.094 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ABK72780.1 - 0.014 15.3 0.2 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Molydop_binding PF01568.21 ABK72780.1 - 0.015 15.3 0.1 0.038 14.0 0.1 1.7 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain SbcCD_C PF13558.6 ABK72780.1 - 0.021 15.0 0.2 0.23 11.7 0.2 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 ABK72780.1 - 0.026 14.7 0.2 0.078 13.1 0.2 2.0 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ABK72780.1 - 0.085 12.9 0.1 0.17 12.0 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 ABK72780.1 - 0.09 13.0 0.1 0.16 12.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 ABK72780.1 - 0.17 11.8 0.0 2.6 8.0 0.0 2.2 2 0 0 2 2 2 0 NTPase AAA_15 PF13175.6 ABK72780.1 - 0.21 11.3 0.0 0.27 10.9 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AMP-binding PF00501.28 ABK72781.1 - 1.2e-98 330.5 0.0 1.4e-98 330.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK72781.1 - 1.6e-18 67.4 0.1 3.7e-18 66.3 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GlnE PF03710.15 ABK72782.1 - 8.2e-103 343.2 0.7 7e-63 212.4 0.0 2.4 2 0 0 2 2 2 2 Glutamate-ammonia ligase adenylyltransferase GlnD_UR_UTase PF08335.11 ABK72782.1 - 4.8e-58 195.4 5.0 4.4e-35 120.9 2.9 2.4 2 0 0 2 2 2 2 GlnD PII-uridylyltransferase DUF294_C PF10335.9 ABK72782.1 - 4.7e-05 23.2 1.6 0.0046 16.7 0.2 2.8 2 0 0 2 2 2 2 Putative nucleotidyltransferase substrate binding domain DUF294 PF03445.13 ABK72782.1 - 0.0066 16.3 0.0 5 6.9 0.0 2.7 2 0 0 2 2 2 2 Putative nucleotidyltransferase DUF294 Acetyltransf_2 PF00797.17 ABK72783.1 - 8.3e-82 274.6 0.0 9.8e-82 274.3 0.0 1.0 1 0 0 1 1 1 1 N-acetyltransferase FA_hydroxylase PF04116.13 ABK72784.1 - 1.8e-26 93.0 7.1 1.8e-26 93.0 7.1 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF4349 PF14257.6 ABK72784.1 - 0.039 13.4 2.2 0.096 12.1 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) DUF202 PF02656.15 ABK72784.1 - 5.1 7.6 7.6 3.8 8.0 5.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Condensation PF00668.20 ABK72785.1 - 4.9e-133 444.1 0.0 1.5e-67 228.3 0.0 2.2 2 0 0 2 2 2 2 Condensation domain AMP-binding PF00501.28 ABK72785.1 - 4.6e-105 351.7 0.0 4.6e-98 328.6 0.0 2.9 2 1 0 2 2 2 2 AMP-binding enzyme PP-binding PF00550.25 ABK72785.1 - 9.7e-29 99.5 1.5 3.4e-14 52.9 0.1 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 ABK72785.1 - 1.6e-09 38.6 0.5 1.6e-09 38.6 0.5 3.5 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Ammonium_transp PF00909.21 ABK72786.1 - 2.2e-121 405.3 36.8 2.6e-121 405.1 36.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Whib PF02467.16 ABK72788.1 - 2e-15 57.1 0.2 2.7e-15 56.7 0.2 1.2 1 0 0 1 1 1 1 Transcription factor WhiB AT_hook PF02178.19 ABK72788.1 - 0.045 13.6 7.1 0.08 12.9 7.1 1.4 1 0 0 1 1 1 0 AT hook motif RFX5_DNA_bdg PF14621.6 ABK72788.1 - 0.078 12.7 0.4 0.099 12.4 0.4 1.2 1 0 0 1 1 1 0 RFX5 DNA-binding domain ALS_ss_C PF10369.9 ABK72789.1 - 3.9e-28 97.5 2.9 6.1e-28 96.8 0.4 2.0 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT_5 PF13710.6 ABK72789.1 - 6.5e-19 67.5 0.9 1.5e-18 66.3 0.1 2.0 2 1 0 2 2 2 1 ACT domain ACT PF01842.25 ABK72789.1 - 1.3e-17 63.3 0.1 3.3e-17 61.9 0.1 1.8 1 1 0 1 1 1 1 ACT domain ACT_4 PF13291.6 ABK72789.1 - 6.5e-09 36.3 1.4 1.3e-08 35.3 0.2 2.0 2 0 0 2 2 2 1 ACT domain Saccharop_dh_N PF04455.12 ABK72789.1 - 0.0017 18.7 0.7 0.041 14.3 0.4 2.2 1 1 0 2 2 2 1 LOR/SDH bifunctional enzyme conserved region THOC7 PF05615.13 ABK72789.1 - 0.016 15.5 0.1 0.02 15.2 0.1 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 ACT_6 PF13740.6 ABK72789.1 - 0.023 14.7 0.4 0.14 12.1 0.1 2.3 2 1 1 3 3 3 0 ACT domain T2SSM_b PF10741.9 ABK72789.1 - 0.18 11.6 1.6 9.8 6.0 0.1 2.2 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M subtype b AA_permease_2 PF13520.6 ABK72790.1 - 8.2e-32 110.6 45.9 1e-31 110.3 45.7 1.2 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ABK72790.1 - 1.3e-18 66.9 42.9 1.8e-18 66.4 42.9 1.2 1 0 0 1 1 1 1 Amino acid permease APH PF01636.23 ABK72791.1 - 4.8e-17 62.7 3.1 7e-17 62.2 3.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 ABK72791.1 - 0.04 13.2 0.0 0.059 12.7 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.20 ABK72791.1 - 0.26 10.9 0.0 0.39 10.3 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase Amidase_2 PF01510.25 ABK72792.1 - 4.1e-19 69.3 0.4 5.5e-19 68.9 0.4 1.2 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase PG_binding_1 PF01471.18 ABK72792.1 - 6.5e-17 61.5 0.0 1.1e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 Putative peptidoglycan binding domain PG_binding_3 PF09374.10 ABK72792.1 - 1.1e-07 32.0 0.6 0.0029 17.9 0.0 2.6 1 1 1 2 2 2 2 Predicted Peptidoglycan domain SnoaL_2 PF12680.7 ABK72793.1 - 1.2e-12 48.3 0.3 2.5e-12 47.3 0.2 1.6 1 1 0 1 1 1 1 SnoaL-like domain Exo_endo_phos PF03372.23 ABK72793.1 - 0.00044 19.8 0.2 0.00049 19.7 0.2 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SnoaL_4 PF13577.6 ABK72793.1 - 0.014 15.5 0.0 0.02 15.0 0.0 1.3 1 1 0 1 1 1 0 SnoaL-like domain SnoaL PF07366.12 ABK72793.1 - 0.019 14.8 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase SnoaL_3 PF13474.6 ABK72793.1 - 0.07 13.4 0.0 0.18 12.0 0.0 1.7 1 1 1 2 2 2 0 SnoaL-like domain Polysacc_deac_1 PF01522.21 ABK72794.1 - 8.1e-22 77.4 0.0 1.2e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase FAD_binding_4 PF01565.23 ABK72795.1 - 5.3e-27 94.3 2.2 5.3e-27 94.3 2.2 1.5 2 0 0 2 2 2 1 FAD binding domain ALO PF04030.14 ABK72795.1 - 1.3e-08 35.0 0.0 1.9e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase AhpC-TSA PF00578.21 ABK72796.1 - 3.6e-18 65.7 0.0 4.8e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ABK72796.1 - 1e-17 64.2 0.0 1.4e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 ABK72796.1 - 3.8e-08 33.6 0.0 5.1e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 ABK72796.1 - 3e-06 27.2 0.0 4.8e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin GSHPx PF00255.19 ABK72796.1 - 0.0055 16.3 0.0 0.0082 15.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase Thioredoxin_2 PF13098.6 ABK72796.1 - 0.0063 16.9 0.0 0.0094 16.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain DLIC PF05783.11 ABK72796.1 - 0.16 10.8 0.0 0.21 10.4 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) YbgT_YccB PF08173.11 ABK72796.1 - 0.44 10.7 2.3 0.81 9.9 2.3 1.4 1 0 0 1 1 1 0 Membrane bound YbgT-like protein HxlR PF01638.17 ABK72797.1 - 4.3e-31 106.6 0.0 5.2e-31 106.3 0.0 1.0 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_20 PF12840.7 ABK72797.1 - 0.00066 19.7 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain DUF2513 PF10711.9 ABK72797.1 - 0.005 17.1 0.0 0.0064 16.8 0.0 1.1 1 0 0 1 1 1 1 Hypothetical protein (DUF2513) PadR PF03551.14 ABK72797.1 - 0.023 14.7 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family HTH_34 PF13601.6 ABK72797.1 - 0.037 14.2 0.0 0.048 13.9 0.0 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_5 PF01022.20 ABK72797.1 - 0.042 13.7 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family B-block_TFIIIC PF04182.12 ABK72797.1 - 0.06 13.5 0.0 0.086 13.0 0.0 1.2 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC HTH_45 PF14947.6 ABK72797.1 - 0.092 12.7 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix SelR PF01641.18 ABK72798.1 - 1.5e-52 176.8 0.0 1.6e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 SelR domain zinc_ribbon_10 PF10058.9 ABK72798.1 - 0.0028 17.3 0.3 0.17 11.6 0.0 2.3 2 0 0 2 2 2 1 Predicted integral membrane zinc-ribbon metal-binding protein Yippee-Mis18 PF03226.14 ABK72798.1 - 0.014 15.6 0.3 0.038 14.2 0.3 1.7 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Ribosomal_L37e PF01907.19 ABK72798.1 - 0.032 14.4 1.7 0.16 12.1 0.4 2.2 2 0 0 2 2 2 0 Ribosomal protein L37e zinc-ribbon_6 PF10005.9 ABK72798.1 - 0.034 14.8 0.7 0.73 10.6 0.0 2.2 1 1 1 2 2 2 0 zinc-ribbon domain DZR PF12773.7 ABK72798.1 - 0.073 13.1 2.1 0.29 11.2 0.9 2.3 1 1 2 3 3 3 0 Double zinc ribbon HECT_2 PF09814.9 ABK72798.1 - 0.077 11.8 0.3 2.9 6.7 0.1 2.0 1 1 1 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding RNA_POL_M_15KD PF02150.16 ABK72798.1 - 0.082 12.8 0.6 2.2 8.2 0.3 2.4 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 ABK72798.1 - 0.12 12.3 1.9 0.64 10.0 0.1 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_2 PF13240.6 ABK72798.1 - 2.6 7.9 5.5 10 6.0 0.8 3.0 3 1 1 4 4 4 0 zinc-ribbon domain Pyr_redox_2 PF07992.14 ABK72799.1 - 4.5e-25 88.5 0.0 7e-25 87.9 0.0 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ABK72799.1 - 2e-06 28.3 0.2 1.1e-05 25.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ABK72799.1 - 2.9e-05 23.5 0.0 0.00055 19.3 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ABK72799.1 - 0.0016 17.7 0.0 0.0028 16.9 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 ABK72799.1 - 0.024 13.7 1.4 0.095 11.7 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 ABK72799.1 - 0.084 12.9 6.0 2.9 7.8 0.1 3.2 2 1 1 3 3 3 0 FAD-NAD(P)-binding DUF2783 PF10932.8 ABK72799.1 - 0.11 12.2 0.1 0.72 9.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2783) DAO PF01266.24 ABK72799.1 - 0.33 10.5 8.3 1.3 8.5 0.1 3.4 4 0 0 4 4 4 0 FAD dependent oxidoreductase HI0933_like PF03486.14 ABK72799.1 - 0.44 9.2 1.3 7.2 5.2 0.1 2.4 2 0 0 2 2 2 0 HI0933-like protein HTH_17 PF12728.7 ABK72800.1 - 0.036 14.3 0.0 0.072 13.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain zf-HC2 PF13490.6 ABK72800.1 - 0.7 10.2 3.4 11 6.4 0.0 3.1 2 1 1 3 3 3 0 Putative zinc-finger GTP_CH_N PF12471.8 ABK72801.1 - 2.1e-79 265.8 0.0 2.8e-79 265.4 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 ABK72801.1 - 6.7e-16 58.3 0.0 9.3e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II NMT1 PF09084.11 ABK72802.1 - 8.3e-46 156.6 0.8 1e-45 156.3 0.8 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 ABK72802.1 - 4.5e-07 29.8 1.8 2.1e-06 27.6 1.8 2.1 1 1 0 1 1 1 1 NMT1-like family NMT1_3 PF16868.5 ABK72802.1 - 4.6e-06 26.3 1.5 3.7e-05 23.3 0.0 2.3 1 1 1 2 2 2 1 NMT1-like family Phosphonate-bd PF12974.7 ABK72802.1 - 9.8e-05 22.1 1.1 0.00015 21.4 1.1 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein LPAM_2 PF13627.6 ABK72802.1 - 6.6 6.7 6.2 12 5.9 6.2 1.5 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site Tautomerase_3 PF14832.6 ABK72803.1 - 2.8e-12 47.0 0.0 3.4e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.21 ABK72803.1 - 2.8e-10 40.0 0.0 0.00057 19.8 0.0 2.1 2 0 0 2 2 2 2 Tautomerase enzyme Tautomerase_2 PF14552.6 ABK72803.1 - 0.0063 16.6 0.0 0.017 15.2 0.0 1.6 2 0 0 2 2 2 1 Tautomerase enzyme AhpC-TSA PF00578.21 ABK72804.1 - 1.2e-15 57.5 0.0 1.3e-15 57.4 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ABK72804.1 - 3.1e-14 52.9 0.0 3.6e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 ABK72804.1 - 0.0031 17.7 0.0 0.0048 17.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 ABK72804.1 - 0.0085 15.9 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 ABK72804.1 - 0.05 13.9 0.0 0.059 13.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like Glutaredoxin PF00462.24 ABK72804.1 - 0.17 12.1 0.1 0.38 11.0 0.1 1.7 1 1 0 1 1 1 0 Glutaredoxin Thioredoxin PF00085.20 ABK72804.1 - 0.21 11.6 0.0 0.33 11.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin SBP_bac_3 PF00497.20 ABK72805.1 - 7.6e-40 136.7 0.0 9e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 SBP_bac_11 PF13531.6 ABK72805.1 - 0.023 14.5 1.8 0.22 11.3 1.8 2.1 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein Lig_chan-Glu_bd PF10613.9 ABK72805.1 - 0.047 13.9 0.0 0.29 11.3 0.0 2.1 1 1 1 2 2 2 0 Ligated ion channel L-glutamate- and glycine-binding site ANTAR PF03861.14 ABK72806.1 - 3.1e-15 55.7 0.2 5.5e-15 54.9 0.2 1.4 1 0 0 1 1 1 1 ANTAR domain PAS_3 PF08447.12 ABK72806.1 - 2.6e-10 40.5 0.1 5e-10 39.5 0.1 1.5 1 1 0 1 1 1 1 PAS fold ALF PF03752.13 ABK72806.1 - 0.037 14.0 0.6 0.97 9.5 0.1 2.5 2 0 0 2 2 2 0 Short repeats of unknown function BPD_transp_1 PF00528.22 ABK72807.1 - 8.4e-16 58.2 12.0 1.2e-15 57.7 12.0 1.2 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component DDE_Tnp_ISL3 PF01610.17 ABK72808.1 - 1.6e-64 217.9 0.0 2.1e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Transposase zf-ISL3 PF14690.6 ABK72808.1 - 1.1e-09 38.8 4.6 1.8e-09 38.1 2.5 2.5 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HTH_Tnp_ISL3 PF13542.6 ABK72808.1 - 2.4e-08 33.2 1.6 7e-08 31.8 1.6 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 SecD_SecF PF02355.16 ABK72809.1 - 4.1e-62 209.0 11.0 7.5e-62 208.1 11.0 1.4 1 0 0 1 1 1 1 Protein export membrane protein Sec_GG PF07549.14 ABK72809.1 - 8.5e-05 21.9 0.1 0.0002 20.7 0.1 1.6 1 0 0 1 1 1 1 SecD/SecF GG Motif DotU PF09850.9 ABK72809.1 - 0.051 13.3 0.2 0.29 10.8 0.0 2.1 2 0 0 2 2 2 0 Type VI secretion system protein DotU RIFIN PF02009.16 ABK72809.1 - 0.1 12.5 0.2 7.9 6.3 0.0 2.4 2 0 0 2 2 2 0 Rifin HXXEE PF13787.6 ABK72809.1 - 2.7 8.8 9.4 2.4 9.0 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function with HXXEE motif CAAD PF14159.6 ABK72809.1 - 8.5 6.3 10.5 0.17 11.8 1.6 2.6 2 1 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase ATP-synt_ab PF00006.25 ABK72810.1 - 2e-67 226.9 0.0 2.9e-67 226.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 ABK72810.1 - 1.3e-50 170.9 0.4 2e-50 170.3 0.4 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 ABK72810.1 - 2.2e-17 63.3 1.8 6e-17 61.9 1.8 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_25 PF13481.6 ABK72810.1 - 0.095 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 ABK72810.1 - 0.23 10.7 0.8 0.61 9.4 0.0 1.9 2 0 0 2 2 2 0 KaiC Methyltransf_31 PF13847.6 ABK72811.1 - 2.3e-15 56.7 0.0 2.9e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABK72811.1 - 1.5e-13 51.2 0.0 2.3e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 ABK72811.1 - 1.9e-12 47.3 0.0 4e-12 46.3 0.0 1.4 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.12 ABK72811.1 - 1.8e-11 44.5 0.0 2.7e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABK72811.1 - 4.5e-11 42.8 0.0 5.7e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK72811.1 - 2.2e-07 31.5 0.0 4.1e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 ABK72811.1 - 2e-05 24.1 0.0 2.7e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.14 ABK72811.1 - 0.00034 20.2 0.0 0.00043 19.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 ABK72811.1 - 0.11 11.8 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DeoRC PF00455.22 ABK72812.1 - 1e-40 139.3 0.0 1.6e-40 138.7 0.0 1.2 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 ABK72812.1 - 4.2e-14 52.0 0.2 8.6e-14 51.0 0.2 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 ABK72812.1 - 1.6e-06 27.9 0.1 3e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 HTH domain HTH_5 PF01022.20 ABK72812.1 - 5.2e-06 26.2 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_23 PF13384.6 ABK72812.1 - 1.1e-05 25.1 0.1 3.7e-05 23.4 0.1 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_20 PF12840.7 ABK72812.1 - 7.2e-05 22.8 0.3 0.00023 21.1 0.1 1.9 2 0 0 2 2 1 1 Helix-turn-helix domain HTH_28 PF13518.6 ABK72812.1 - 0.00031 20.8 0.0 0.00078 19.5 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 ABK72812.1 - 0.00032 20.2 0.2 0.00072 19.1 0.2 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_29 PF13551.6 ABK72812.1 - 0.00038 20.4 0.1 0.00088 19.2 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_AsnC-type PF13404.6 ABK72812.1 - 0.00085 19.1 0.3 0.0026 17.6 0.3 1.9 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 ABK72812.1 - 0.00088 18.6 0.0 0.0031 16.9 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 Put_DNA-bind_N PF06971.13 ABK72812.1 - 0.0018 18.2 0.1 0.0039 17.2 0.1 1.6 1 0 0 1 1 1 1 Putative DNA-binding protein N-terminus Sigma70_r4 PF04545.16 ABK72812.1 - 0.0024 17.4 0.2 0.0056 16.2 0.2 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 GntR PF00392.21 ABK72812.1 - 0.0026 17.4 0.2 0.0085 15.7 0.2 2.0 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_38 PF13936.6 ABK72812.1 - 0.003 17.3 0.5 0.0069 16.1 0.1 1.8 2 0 0 2 2 1 1 Helix-turn-helix domain MarR_2 PF12802.7 ABK72812.1 - 0.0044 16.9 0.4 0.019 14.8 0.4 2.1 1 0 0 1 1 1 1 MarR family HTH_7 PF02796.15 ABK72812.1 - 0.0063 16.6 0.0 0.022 14.8 0.0 1.9 2 0 0 2 2 1 1 Helix-turn-helix domain of resolvase HTH_Tnp_1 PF01527.20 ABK72812.1 - 0.0069 16.7 0.1 0.018 15.4 0.1 1.7 1 0 0 1 1 1 1 Transposase MarR PF01047.22 ABK72812.1 - 0.01 15.8 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 MarR family PaaX PF07848.12 ABK72812.1 - 0.019 15.2 0.1 0.054 13.7 0.1 1.7 2 0 0 2 2 1 0 PaaX-like protein HTH_47 PF16221.5 ABK72812.1 - 0.025 14.1 0.2 0.12 11.9 0.1 2.0 2 0 0 2 2 2 0 winged helix-turn-helix HTH_IclR PF09339.10 ABK72812.1 - 0.033 14.0 0.3 0.063 13.1 0.3 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain GerE PF00196.19 ABK72812.1 - 0.035 13.7 0.0 0.087 12.4 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_36 PF13730.6 ABK72812.1 - 0.04 13.9 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_31 PF13560.6 ABK72812.1 - 0.046 14.1 2.0 0.11 12.9 0.1 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain Head-tail_con PF12236.8 ABK72812.1 - 0.061 11.8 0.2 0.12 10.9 0.1 1.4 2 0 0 2 2 2 0 Bacteriophage head to tail connecting protein MerR PF00376.23 ABK72812.1 - 0.094 12.5 0.1 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 MerR family regulatory protein HTH_22 PF13309.6 ABK72812.1 - 0.14 12.3 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 HTH domain SpoIIID PF12116.8 ABK72812.1 - 0.15 12.2 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Stage III sporulation protein D AbiEi_4 PF13338.6 ABK72812.1 - 0.15 12.3 1.0 0.46 10.7 0.3 2.3 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin DUF4423 PF14394.6 ABK72812.1 - 0.22 11.2 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) DDE_Tnp_ISL3 PF01610.17 ABK72813.1 - 1.6e-64 217.9 0.0 2.1e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Transposase zf-ISL3 PF14690.6 ABK72813.1 - 1.1e-09 38.8 4.6 1.8e-09 38.1 2.5 2.5 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HTH_Tnp_ISL3 PF13542.6 ABK72813.1 - 2.4e-08 33.2 1.6 7e-08 31.8 1.6 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 BPD_transp_1 PF00528.22 ABK72814.1 - 9.8e-38 129.7 12.9 9.8e-38 129.7 12.9 2.2 2 1 1 3 3 3 1 Binding-protein-dependent transport system inner membrane component HATPase_c_2 PF13581.6 ABK72815.1 - 4.9e-20 71.7 0.1 6.5e-20 71.4 0.1 1.2 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Abhydrolase_1 PF00561.20 ABK72816.1 - 1.1e-23 84.2 0.1 5e-23 82.0 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK72816.1 - 1.5e-16 61.7 17.9 1.8e-16 61.5 17.9 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK72816.1 - 2.1e-06 27.2 0.0 6.2e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 ABK72816.1 - 1.1e-05 24.3 0.0 5.4e-05 22.0 0.0 1.8 1 1 0 1 1 1 1 Ndr family Hexapep PF00132.24 ABK72817.1 - 1.2e-09 37.4 8.2 1.5e-07 30.9 0.4 3.5 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 ABK72817.1 - 0.027 14.2 5.2 0.88 9.4 0.3 3.3 3 1 1 4 4 4 0 Hexapeptide repeat of succinyl-transferase Lyase_1 PF00206.20 ABK72818.1 - 7.7e-97 324.4 0.0 1e-96 324.1 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 ABK72818.1 - 6.3e-14 52.1 0.1 1.9e-13 50.6 0.1 1.9 1 0 0 1 1 1 1 Fumarase C C-terminus TetR_N PF00440.23 ABK72819.1 - 3.4e-10 39.5 0.2 6.3e-10 38.7 0.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 ABK72819.1 - 0.038 14.2 7.6 0.16 12.2 0.2 2.2 2 0 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal TetR_C_31 PF17940.1 ABK72819.1 - 0.42 10.8 9.6 0.1 12.8 2.1 2.9 2 2 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DivIVA PF05103.13 ABK72820.1 - 8.5e-22 77.7 19.6 1.8e-12 47.5 0.0 3.3 2 1 1 3 3 3 3 DivIVA protein Apolipoprotein PF01442.18 ABK72820.1 - 0.00055 19.9 22.5 0.00055 19.9 22.5 2.1 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain UPF0242 PF06785.11 ABK72820.1 - 0.012 15.7 8.1 0.59 10.2 6.9 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Shugoshin_N PF07558.11 ABK72820.1 - 0.014 15.2 0.9 0.032 14.1 0.9 1.6 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Pox_A_type_inc PF04508.12 ABK72820.1 - 0.02 14.8 0.2 0.35 10.8 0.0 2.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat HrpE PF06188.12 ABK72820.1 - 0.072 13.0 23.7 0.23 11.3 3.7 3.2 2 1 1 3 3 3 0 HrpE/YscL/FliH and V-type ATPase subunit E V-ATPase_G_2 PF16999.5 ABK72820.1 - 0.14 12.6 35.2 0.096 13.1 17.8 4.4 2 1 2 4 4 4 0 Vacuolar (H+)-ATPase G subunit DUF4094 PF13334.6 ABK72820.1 - 0.6 10.6 4.9 2.7 8.5 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) Cnn_1N PF07989.11 ABK72820.1 - 0.8 9.9 0.0 0.8 9.9 0.0 3.0 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 Exonuc_VII_L PF02601.15 ABK72820.1 - 3.3 7.2 13.5 1.7 8.2 11.2 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit Baculo_LEF-10 PF07206.11 ABK72820.1 - 3.5 7.9 7.0 1 9.5 0.9 2.8 1 1 2 3 3 3 0 Baculovirus late expression factor 10 (LEF-10) DUF883 PF05957.13 ABK72820.1 - 4.2 8.0 27.7 0.078 13.6 10.1 3.6 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF883) Jnk-SapK_ap_N PF09744.9 ABK72820.1 - 5 7.3 16.0 0.92 9.7 9.4 2.5 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 ApoLp-III PF07464.11 ABK72820.1 - 5 7.2 12.1 2.9 8.0 9.2 1.9 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DASH_Spc19 PF08287.11 ABK72820.1 - 9.3 6.1 19.9 0.73 9.7 0.1 2.9 2 1 1 3 3 3 0 Spc19 Methyltransf_24 PF13578.6 ABK72821.1 - 1.4e-22 80.7 0.6 2.1e-22 80.1 0.6 1.3 1 0 0 1 1 1 1 Methyltransferase domain Herpes_UL21 PF03252.13 ABK72821.1 - 0.028 13.2 0.0 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL21 EHN PF06441.12 ABK72822.1 - 3.2e-30 104.7 0.0 5.4e-30 103.9 0.0 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 ABK72822.1 - 3.2e-14 53.2 0.1 5.9e-14 52.3 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK72822.1 - 1.2e-06 29.3 10.1 1.2e-06 29.3 10.1 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family CPSase_L_D2 PF02786.17 ABK72823.1 - 2.6e-72 242.7 0.0 4e-72 242.1 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ABK72823.1 - 3.5e-43 146.6 1.4 2.9e-42 143.7 0.1 2.6 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ABK72823.1 - 4.5e-36 123.2 0.0 2.7e-35 120.8 0.0 2.3 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 ABK72823.1 - 1.3e-18 66.6 3.2 8.8e-18 63.9 3.9 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 ABK72823.1 - 3.2e-15 56.2 0.0 5.7e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 ABK72823.1 - 2.9e-12 46.2 7.1 5.1e-07 29.4 1.5 2.9 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 ABK72823.1 - 5.2e-07 29.4 0.0 9.5e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 ABK72823.1 - 0.00011 22.8 4.6 0.00048 20.8 0.6 2.9 3 0 0 3 3 3 1 HlyD family secretion protein HlyD_D23 PF16576.5 ABK72823.1 - 0.00014 21.1 1.0 0.0076 15.5 0.2 2.3 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_3 PF02655.14 ABK72823.1 - 0.0059 16.7 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Peptidase_M23 PF01551.22 ABK72823.1 - 0.0078 16.4 0.2 0.037 14.2 0.2 2.2 1 0 0 1 1 1 1 Peptidase family M23 QRPTase_N PF02749.16 ABK72823.1 - 0.0095 16.0 2.9 1.3 9.1 0.1 3.6 2 1 1 3 3 3 1 Quinolinate phosphoribosyl transferase, N-terminal domain DUF3182 PF11379.8 ABK72823.1 - 0.013 14.5 0.1 0.035 13.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) DUF2118 PF09891.9 ABK72823.1 - 0.014 15.3 1.8 0.061 13.3 0.4 2.5 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2118) ATPgrasp_N PF18130.1 ABK72823.1 - 0.02 15.5 1.7 5.2 7.7 0.0 3.9 4 0 0 4 4 4 0 ATP-grasp N-terminal domain GARS_A PF01071.19 ABK72823.1 - 0.026 14.3 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RnfC_N PF13375.6 ABK72823.1 - 0.048 13.6 4.9 2 8.4 0.5 3.3 2 1 1 3 3 3 0 RnfC Barrel sandwich hybrid domain Transp_cyt_pur PF02133.15 ABK72824.1 - 5.7e-45 153.9 44.5 7.7e-45 153.5 44.5 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF808 PF05661.12 ABK72825.1 - 9.5e-127 422.2 16.3 1.1e-126 422.0 16.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF808) LapA_dom PF06305.11 ABK72825.1 - 3.7 7.4 10.9 13 5.7 0.2 3.5 2 1 1 3 3 3 0 Lipopolysaccharide assembly protein A domain NHase_beta PF02211.15 ABK72826.1 - 1.9e-77 260.2 0.0 2.2e-77 260.0 0.0 1.0 1 0 0 1 1 1 1 Nitrile hydratase beta subunit Inos-1-P_synth PF01658.17 ABK72827.1 - 1.1e-31 109.3 0.0 5e-31 107.2 0.0 1.9 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase NAD_binding_5 PF07994.12 ABK72827.1 - 0.0074 15.7 0.0 0.11 11.8 0.0 2.1 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase DUF1611_N PF17396.2 ABK72827.1 - 0.062 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_N) Rossmann-like domain Bac_luciferase PF00296.20 ABK72828.1 - 2.4e-31 109.3 3.3 2e-29 103.0 3.2 2.6 1 1 0 1 1 1 1 Luciferase-like monooxygenase Isochorismatase PF00857.20 ABK72828.1 - 0.02 15.1 0.1 0.037 14.2 0.1 1.4 1 0 0 1 1 1 0 Isochorismatase family Response_reg PF00072.24 ABK72829.1 - 1.9e-21 76.3 0.1 3.1e-21 75.6 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 ABK72829.1 - 6e-21 73.8 0.2 1.3e-20 72.6 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 ABK72829.1 - 5.1e-06 26.1 0.3 6.3e-05 22.6 0.1 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 ABK72829.1 - 4.2e-05 23.0 0.7 9.1e-05 21.9 0.4 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_38 PF13936.6 ABK72829.1 - 8.2e-05 22.3 0.9 0.00034 20.3 0.3 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 ABK72829.1 - 0.00021 21.0 2.7 0.00042 20.0 0.2 2.8 4 0 0 4 4 4 1 Homeodomain-like domain HTH_20 PF12840.7 ABK72829.1 - 0.00021 21.3 0.3 0.00096 19.2 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_28 PF13518.6 ABK72829.1 - 0.00067 19.7 0.4 0.012 15.7 0.2 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_11 PF08279.12 ABK72829.1 - 0.0012 18.8 0.2 0.0035 17.2 0.2 1.8 1 0 0 1 1 1 1 HTH domain HTH_40 PF14493.6 ABK72829.1 - 0.0025 18.3 0.1 0.0072 16.8 0.2 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain Ntox27 PF15531.6 ABK72829.1 - 0.019 14.9 0.1 0.037 13.9 0.1 1.5 1 0 0 1 1 1 0 Bacterial toxin 27 Hydrolase_like PF13242.6 ABK72829.1 - 0.031 14.3 1.2 0.71 10.0 0.1 2.5 2 1 0 2 2 2 0 HAD-hyrolase-like HTH_24 PF13412.6 ABK72829.1 - 0.036 13.6 0.6 0.072 12.7 0.1 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding B12-binding PF02310.19 ABK72829.1 - 0.042 13.9 1.2 0.14 12.2 0.4 2.1 1 1 1 2 2 2 0 B12 binding domain Sigma70_ECF PF07638.11 ABK72829.1 - 0.053 13.4 0.1 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 ECF sigma factor HTH_10 PF04967.12 ABK72829.1 - 0.054 13.3 1.1 0.84 9.5 1.1 2.6 1 1 0 1 1 1 0 HTH DNA binding domain HU-CCDC81_euk_2 PF18289.1 ABK72829.1 - 0.075 13.2 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 HTH_29 PF13551.6 ABK72829.1 - 0.11 12.5 0.5 0.75 9.9 0.1 2.4 2 0 0 2 2 2 0 Winged helix-turn helix DUF4510 PF14971.6 ABK72829.1 - 0.2 12.0 2.9 0.31 11.4 2.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4510) DUF520 PF04461.13 ABK72830.1 - 4e-62 209.1 4.6 4.5e-62 208.9 4.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF520) Microtub_bd PF16796.5 ABK72830.1 - 0.012 15.6 0.1 0.014 15.3 0.1 1.2 1 0 0 1 1 1 0 Microtubule binding GGDEF PF00990.21 ABK72830.1 - 0.036 13.8 0.5 0.61 9.8 0.1 2.0 1 1 0 2 2 2 0 Diguanylate cyclase, GGDEF domain DUF2974 PF11187.8 ABK72830.1 - 0.091 12.3 0.4 0.16 11.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) ABC2_membrane_4 PF12730.7 ABK72831.1 - 0.096 12.6 12.6 0.25 11.3 12.6 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF2070 PF09843.9 ABK72831.1 - 4 5.6 11.0 4.7 5.4 11.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) YjbR PF04237.13 ABK72832.1 - 9.7e-16 58.1 0.0 1.2e-15 57.8 0.0 1.1 1 0 0 1 1 1 1 YjbR Big_9 PF17963.1 ABK72833.1 - 5.1e-10 40.0 3.8 6e-10 39.7 3.8 1.0 1 0 0 1 1 1 1 Bacterial Ig domain Cadherin_4 PF17803.1 ABK72833.1 - 7.6e-10 39.3 2.8 9.3e-10 39.0 2.8 1.1 1 0 0 1 1 1 1 Bacterial cadherin-like domain Glycos_transf_1 PF00534.20 ABK72834.1 - 1.1e-23 83.6 0.0 2.2e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ABK72834.1 - 2.6e-23 82.9 0.3 1.4e-22 80.5 0.1 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ABK72834.1 - 2.3e-17 63.5 3.1 3.1e-17 63.1 2.2 1.7 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 ABK72834.1 - 2.2e-16 60.7 8.9 2.2e-16 60.7 8.9 2.3 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 ABK72834.1 - 1.6e-06 28.4 0.0 4.9e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 ABK72834.1 - 1.5e-05 25.1 0.0 2.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like PRiA4_ORF3 PF07929.11 ABK72835.1 - 2.1e-51 174.1 0.0 2.5e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein PfkB PF00294.24 ABK72836.1 - 1e-46 159.6 0.0 1.3e-46 159.3 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase MlaD PF02470.20 ABK72837.1 - 6.3e-15 55.2 0.0 1.2e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 MlaD protein Mce4_CUP1 PF11887.8 ABK72837.1 - 2e-09 37.3 2.7 3.3e-09 36.6 2.7 1.3 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative Baculo_PEP_C PF04513.12 ABK72837.1 - 0.00066 19.7 5.6 0.5 10.4 0.1 2.2 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Sec8_exocyst PF04048.14 ABK72837.1 - 0.0012 18.7 0.3 0.28 11.1 0.0 2.7 1 1 1 2 2 2 1 Sec8 exocyst complex component specific domain Serine_rich PF08824.10 ABK72837.1 - 0.0041 17.1 0.4 0.0078 16.2 0.4 1.4 1 0 0 1 1 1 1 Serine rich protein interaction domain Apolipoprotein PF01442.18 ABK72837.1 - 0.028 14.3 0.4 3.3 7.5 0.0 2.1 1 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain DASH_Dam1 PF08653.10 ABK72837.1 - 0.045 13.5 2.8 2.6 7.9 0.3 3.2 2 1 1 3 3 3 0 DASH complex subunit Dam1 DUF1664 PF07889.12 ABK72837.1 - 0.065 13.3 0.1 2.9 7.9 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 ABK72837.1 - 0.12 12.6 2.7 5.6 7.3 0.6 2.7 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) APG17 PF04108.12 ABK72837.1 - 0.15 11.2 0.2 0.87 8.6 0.2 1.5 1 1 0 1 1 1 0 Autophagy protein Apg17 WXG100 PF06013.12 ABK72837.1 - 0.29 11.4 3.4 12 6.2 0.2 3.3 1 1 2 3 3 3 0 Proteins of 100 residues with WXG NPV_P10 PF05531.12 ABK72837.1 - 1.4 9.4 6.0 8.5 6.9 0.2 2.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein MDMPI_N PF11716.8 ABK72839.1 - 5.5e-27 95.2 8.8 5.5e-27 95.2 8.8 1.8 2 1 0 2 2 2 1 Mycothiol maleylpyruvate isomerase N-terminal domain DinB_2 PF12867.7 ABK72839.1 - 4.9e-06 27.1 4.9 7.3e-06 26.5 2.2 2.0 2 0 0 2 2 2 1 DinB superfamily MDMPI_C PF07398.11 ABK72839.1 - 1.2e-05 26.1 2.6 1.2e-05 26.1 2.6 2.3 2 1 0 2 2 2 1 MDMPI C-terminal domain Wyosine_form PF08608.12 ABK72839.1 - 0.00024 21.4 0.0 0.0014 19.0 0.0 2.1 1 1 1 2 2 2 1 Wyosine base formation DinB PF05163.12 ABK72839.1 - 0.017 15.1 0.0 0.034 14.1 0.0 1.7 1 1 0 1 1 1 0 DinB family Arabinose_trans PF04602.12 ABK72840.1 - 5.7e-195 648.5 39.7 8.1e-195 648.0 39.7 1.2 1 0 0 1 1 1 1 Mycobacterial cell wall arabinan synthesis protein Arabino_trans_C PF14896.6 ABK72840.1 - 6.9e-145 482.9 1.3 1.3e-144 482.0 0.4 1.9 2 1 0 2 2 2 1 EmbC C-terminal domain Arabino_trans_N PF17689.1 ABK72840.1 - 2.5e-56 190.2 0.7 3.8e-56 189.6 0.7 1.3 1 0 0 1 1 1 1 Arabinosyltransferase concanavalin like domain OppC_N PF12911.7 ABK72840.1 - 3.8 7.6 8.1 1.1 9.3 0.3 3.8 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C SSF PF00474.17 ABK72841.1 - 8.4e-95 318.0 39.8 1.1e-94 317.7 39.8 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family DUF2818 PF10993.8 ABK72841.1 - 0.14 12.8 0.2 0.14 12.8 0.2 3.4 3 2 1 4 4 4 0 Protein of unknown function (DUF2818) TP_methylase PF00590.20 ABK72842.1 - 6.5e-17 62.2 1.7 4.3e-16 59.5 1.7 2.0 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases PCMT PF01135.19 ABK72842.1 - 0.0015 18.3 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 ABK72842.1 - 0.044 13.4 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MFS_1 PF07690.16 ABK72843.1 - 6.5e-44 150.3 53.9 6.5e-44 150.3 53.9 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK72843.1 - 1.2e-10 40.9 36.5 1.6e-09 37.1 15.6 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 ABK72843.1 - 2.3e-05 23.9 42.0 3.3e-05 23.4 42.0 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 ABK72843.1 - 7.1 4.8 17.7 0.59 8.4 3.0 2.9 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DoxX_2 PF13564.6 ABK72844.1 - 0.019 15.1 0.2 0.023 14.8 0.2 1.1 1 0 0 1 1 1 0 DoxX-like family Oxidored_q2 PF00420.24 ABK72845.1 - 3.6e-24 84.4 8.2 4.3e-24 84.1 8.2 1.0 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Pox_A14 PF05767.12 ABK72845.1 - 0.063 13.4 3.0 0.096 12.9 3.0 1.4 1 1 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF5353 PF17304.2 ABK72845.1 - 0.41 10.4 2.6 0.3 10.9 0.5 1.8 2 1 1 3 3 3 0 Family of unknown function (DUF5353) PEP-CTERM PF07589.11 ABK72845.1 - 2.6 8.2 5.1 0.9 9.7 0.6 2.3 2 0 0 2 2 2 0 PEP-CTERM motif adh_short PF00106.25 ABK72846.1 - 3.6e-52 176.7 0.0 4.9e-52 176.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK72846.1 - 2.1e-46 158.4 0.5 2.9e-46 157.9 0.5 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK72846.1 - 1.4e-11 44.7 0.0 2e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK72846.1 - 6.5e-08 32.3 0.0 1.3e-07 31.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ApbA PF02558.16 ABK72846.1 - 0.0035 17.0 0.2 0.0051 16.5 0.2 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.6 ABK72846.1 - 0.0039 17.1 1.8 0.014 15.3 0.3 2.0 2 0 0 2 2 2 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 ABK72846.1 - 0.016 14.3 0.2 0.023 13.8 0.2 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain 3HCDH_N PF02737.18 ABK72846.1 - 0.028 14.3 0.2 0.044 13.7 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CMD PF02627.20 ABK72846.1 - 0.033 14.3 5.0 1.4 9.0 0.7 2.6 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family Shikimate_DH PF01488.20 ABK72846.1 - 0.063 13.3 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 ABK72846.1 - 0.12 12.3 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAA_hydrolase PF01557.18 ABK72848.1 - 7e-61 205.7 0.0 8.7e-61 205.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DctP PF03480.13 ABK72849.1 - 3.3e-75 253.1 0.0 4.1e-75 252.8 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein, family 7 TAT_signal PF10518.9 ABK72849.1 - 0.036 13.9 11.0 0.081 12.8 11.0 1.6 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence K_channel_TID PF07941.11 ABK72849.1 - 0.28 11.6 5.3 0.52 10.8 5.3 1.4 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Aminotran_1_2 PF00155.21 ABK72850.1 - 1.1e-44 153.1 0.0 2.2e-44 152.1 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II UPF0052 PF01933.18 ABK72851.1 - 2.3e-69 233.9 0.0 2.8e-69 233.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 TOBE_3 PF12857.7 ABK72851.1 - 0.02 14.8 2.1 1.1 9.2 0.3 2.9 2 0 0 2 2 2 0 TOBE-like domain ABC_tran PF00005.27 ABK72852.1 - 8.9e-29 100.8 0.0 1.1e-28 100.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK72852.1 - 4.4e-07 30.0 0.3 0.011 15.6 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ABK72852.1 - 3.5e-05 23.4 0.1 7.1e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 ABK72852.1 - 0.001 19.6 0.1 0.0018 18.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ABK72852.1 - 0.0012 18.6 1.2 0.0024 17.6 1.2 1.5 1 1 0 1 1 1 1 AAA domain DUF3584 PF12128.8 ABK72852.1 - 0.012 13.2 0.1 0.018 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ATP-synt_F PF01990.17 ABK72852.1 - 0.022 15.1 0.0 0.042 14.2 0.0 1.4 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit SMC_N PF02463.19 ABK72852.1 - 0.024 14.1 0.2 0.087 12.2 0.2 1.8 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ABK72852.1 - 0.032 14.5 0.3 0.078 13.3 0.3 1.8 1 1 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 ABK72852.1 - 0.034 12.9 0.5 0.13 11.0 0.4 1.8 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_27 PF13514.6 ABK72852.1 - 0.037 13.6 0.5 0.082 12.5 0.1 1.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 ABK72852.1 - 0.055 12.7 0.0 0.082 12.2 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 ABK72852.1 - 0.065 12.8 0.4 0.14 11.7 0.4 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ABK72852.1 - 0.076 13.4 0.9 0.15 12.4 0.8 1.7 1 1 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 ABK72852.1 - 0.13 11.8 0.7 0.27 10.8 0.3 1.7 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 ABK72852.1 - 0.13 12.3 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 ABK72852.1 - 0.21 11.7 0.4 0.34 11.0 0.4 1.6 1 1 0 1 1 1 0 AAA domain Pep_deformylase PF01327.21 ABK72853.1 - 4.7e-38 130.3 0.0 5.9e-38 130.0 0.0 1.0 1 0 0 1 1 1 1 Polypeptide deformylase NmrA PF05368.13 ABK72854.1 - 2.3e-16 60.1 0.0 3e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ABK72854.1 - 4e-08 33.4 0.3 7.5e-08 32.5 0.1 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 ABK72854.1 - 2.2e-06 27.9 0.6 4.1e-06 27.1 0.3 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Glu_dehyd_C PF16912.5 ABK72854.1 - 0.0085 15.6 0.1 0.021 14.3 0.0 1.6 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus Shikimate_DH PF01488.20 ABK72854.1 - 0.017 15.2 0.3 0.045 13.8 0.3 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.22 ABK72854.1 - 0.024 15.5 0.1 0.045 14.6 0.1 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.18 ABK72854.1 - 0.086 13.1 0.2 0.17 12.2 0.2 1.5 1 0 0 1 1 1 0 TrkA-N domain AMP-binding PF00501.28 ABK72855.1 - 3.3e-69 233.5 0.1 4.4e-69 233.1 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C_2 PF14535.6 ABK72855.1 - 2.2e-06 27.9 0.0 3.8e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HNH PF01844.23 ABK72856.1 - 1.6e-12 47.4 1.6 2.9e-12 46.6 1.6 1.4 1 0 0 1 1 1 1 HNH endonuclease HNH_5 PF14279.6 ABK72856.1 - 2.1e-12 46.7 0.3 3.2e-12 46.1 0.3 1.3 1 0 0 1 1 1 1 HNH endonuclease HNH_4 PF13395.6 ABK72856.1 - 7.6e-07 28.9 0.0 1.8e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 HNH endonuclease adh_short_C2 PF13561.6 ABK72857.1 - 4.4e-62 209.7 1.6 5.1e-62 209.5 1.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK72857.1 - 1.3e-47 161.8 0.1 1.7e-47 161.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK72857.1 - 7.6e-11 42.2 0.0 1.2e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 ABK72857.1 - 0.0048 16.8 0.4 0.0082 16.1 0.4 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 ABK72857.1 - 0.022 14.8 0.2 0.044 13.8 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase BAT PF15915.5 ABK72857.1 - 0.023 14.6 1.2 0.052 13.4 1.2 1.5 1 0 0 1 1 1 0 GAF and HTH_10 associated domain NAD_binding_10 PF13460.6 ABK72857.1 - 0.03 14.2 2.6 0.039 13.8 2.6 1.3 1 1 0 1 1 1 0 NAD(P)H-binding Oxidored_nitro PF00148.19 ABK72857.1 - 0.033 12.9 0.1 0.067 11.9 0.1 1.4 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase THF_DHG_CYH_C PF02882.19 ABK72857.1 - 0.048 13.0 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.19 ABK72857.1 - 0.14 11.5 0.7 0.23 10.8 0.2 1.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Abhydrolase_1 PF00561.20 ABK72858.1 - 1.8e-24 86.8 0.1 4.8e-24 85.4 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Trans_reg_C PF00486.28 ABK72858.1 - 6.2e-17 61.4 0.0 1.2e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Hydrolase_4 PF12146.8 ABK72858.1 - 4.9e-14 52.2 0.3 2.8e-13 49.7 0.3 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 ABK72858.1 - 8.7e-06 24.6 0.0 1.2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Ndr family Palm_thioest PF02089.15 ABK72858.1 - 0.0055 16.6 0.0 0.0071 16.2 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Esterase PF00756.20 ABK72858.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.21 ABK72858.1 - 0.015 14.8 0.0 0.41 10.1 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 ABK72858.1 - 0.081 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family NusB PF01029.18 ABK72859.1 - 3.2e-35 121.3 0.0 3.8e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 NusB family Polyketide_cyc2 PF10604.9 ABK72860.1 - 5.1e-07 30.1 1.2 6e-07 29.8 1.2 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 ABK72860.1 - 0.072 13.3 0.1 0.1 12.8 0.1 1.3 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Abhydrolase_6 PF12697.7 ABK72861.1 - 2.7e-14 54.3 14.3 2.7e-14 54.3 14.3 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ABK72861.1 - 5.7e-10 39.3 0.1 3.4e-08 33.5 0.2 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ABK72861.1 - 9.9e-06 25.0 0.0 2.4e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 EthD PF07110.11 ABK72862.1 - 3.1e-11 44.2 0.5 4.7e-11 43.7 0.5 1.3 1 0 0 1 1 1 1 EthD domain Dabb PF07876.12 ABK72862.1 - 1.6e-05 25.5 0.0 1.9e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain MmlI PF09448.10 ABK72862.1 - 0.012 16.0 0.0 0.057 13.9 0.0 1.9 1 1 0 1 1 1 0 Methylmuconolactone methyl-isomerase Pribosyltran PF00156.27 ABK72863.1 - 4.6e-21 75.0 0.0 5.4e-21 74.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 ABK72863.1 - 0.0018 17.7 0.0 0.0023 17.4 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase 2-oxoacid_dh PF00198.23 ABK72864.1 - 7.2e-69 231.8 0.0 9.4e-69 231.4 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 ABK72864.1 - 9.4e-19 67.0 0.0 1.6e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 ABK72864.1 - 5.5e-12 45.8 1.2 1.3e-11 44.6 1.2 1.7 1 0 0 1 1 1 1 e3 binding domain GCV_H PF01597.19 ABK72864.1 - 0.091 12.7 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycine cleavage H-protein Hydrolase_4 PF12146.8 ABK72865.1 - 2.7e-36 125.0 0.1 5.5e-35 120.8 0.1 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ABK72865.1 - 3.8e-10 40.7 7.4 5.4e-10 40.2 7.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ABK72865.1 - 1.2e-09 38.2 0.2 5.6e-06 26.2 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ABK72865.1 - 3.5e-06 26.6 0.0 5.7e-06 25.9 0.0 1.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 ABK72865.1 - 0.0012 18.6 0.0 1.6 8.5 0.0 3.0 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 ABK72865.1 - 0.029 14.0 0.0 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase (FSH1) PAF-AH_p_II PF03403.13 ABK72865.1 - 0.088 11.3 0.0 3.5 6.0 0.0 2.1 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II MFS_1 PF07690.16 ABK72866.1 - 1.8e-26 92.9 60.8 1.1e-19 70.6 38.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 ABK72866.1 - 0.00058 18.8 2.7 0.00058 18.8 2.7 2.1 2 1 0 2 2 2 1 MFS_1 like family HSP70 PF00012.20 ABK72867.1 - 9.8e-21 73.6 0.0 1.3e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ABK72867.1 - 8e-05 21.6 0.0 0.00013 20.9 0.0 1.4 1 0 0 1 1 1 1 MreB/Mbl protein DUF5129 PF17173.4 ABK72867.1 - 0.11 11.6 1.0 0.22 10.6 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5129) adh_short_C2 PF13561.6 ABK72869.1 - 3.8e-61 206.6 1.6 5.2e-61 206.2 1.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK72869.1 - 6.9e-50 169.2 0.7 8.1e-50 169.0 0.7 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK72869.1 - 1.2e-13 51.4 0.9 1.7e-13 50.9 0.9 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK72869.1 - 3.6e-12 46.3 0.9 1.1e-10 41.4 0.8 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ABK72869.1 - 4.1e-10 39.6 0.1 6.5e-08 32.3 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 ABK72869.1 - 2.9e-07 30.8 0.1 4.5e-07 30.2 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 ABK72869.1 - 5.1e-06 26.5 2.4 6.9e-06 26.1 2.4 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ABK72869.1 - 0.00067 19.3 0.6 0.001 18.7 0.6 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 ABK72869.1 - 0.0012 18.1 0.0 0.0015 17.8 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 ABK72869.1 - 0.0014 17.8 0.3 0.0023 17.1 0.3 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 ABK72869.1 - 0.0023 17.2 0.8 0.1 11.7 0.1 2.2 1 1 1 2 2 2 1 Male sterility protein THF_DHG_CYH_C PF02882.19 ABK72869.1 - 0.013 14.8 0.0 0.37 10.1 0.0 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 ABK72869.1 - 0.02 15.0 0.0 0.03 14.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AdoHcyase_NAD PF00670.21 ABK72869.1 - 0.084 12.9 1.1 0.26 11.3 1.1 1.8 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Methyltransf_25 PF13649.6 ABK72869.1 - 0.12 13.1 0.1 0.21 12.3 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_7 PF13241.6 ABK72869.1 - 0.19 12.2 1.0 0.55 10.7 1.0 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding adh_short_C2 PF13561.6 ABK72870.1 - 3.8e-50 170.6 6.1 2.2e-48 164.9 6.1 2.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK72870.1 - 2.2e-49 167.6 1.4 2e-48 164.5 1.4 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK72870.1 - 1.1e-14 54.7 0.4 1.7e-14 54.1 0.4 1.2 1 0 0 1 1 1 1 KR domain NUDIX PF00293.28 ABK72871.1 - 2.5e-18 66.4 0.0 4.8e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 ABK72871.1 - 2.2e-07 31.5 0.9 3.9e-07 30.7 0.9 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 ABK72871.1 - 6.6e-06 25.7 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Aldose_epim PF01263.20 ABK72872.1 - 2.3e-23 83.0 0.0 2.7e-23 82.7 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Response_reg PF00072.24 ABK72873.1 - 4e-29 101.0 0.0 6.1e-29 100.4 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 ABK72873.1 - 3.3e-27 94.4 0.1 6.3e-27 93.5 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal OKR_DC_1_N PF03709.15 ABK72873.1 - 0.0041 17.4 0.0 0.0082 16.4 0.0 1.4 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, N-terminal domain Acyl_transf_1 PF00698.21 ABK72874.1 - 7e-23 81.6 7.2 8.7e-23 81.3 7.2 1.1 1 0 0 1 1 1 1 Acyl transferase domain PRiA4_ORF3 PF07929.11 ABK72875.1 - 2.1e-51 174.1 0.0 2.5e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein Formyl_trans_N PF00551.19 ABK72876.1 - 9.6e-28 97.1 0.0 1.3e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 ABK72876.1 - 5.5e-15 55.4 0.0 8.3e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain B12-binding PF02310.19 ABK72876.1 - 0.027 14.5 0.0 0.067 13.2 0.0 1.7 1 0 0 1 1 1 0 B12 binding domain Oxidored_nitro PF00148.19 ABK72876.1 - 0.17 10.6 0.0 0.24 10.1 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase AMP-binding PF00501.28 ABK72877.1 - 1.1e-79 268.0 0.0 2.7e-78 263.4 0.0 2.2 1 1 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 ABK72877.1 - 2.5e-68 230.8 0.0 5.1e-60 203.4 0.0 2.2 2 0 0 2 2 2 2 Condensation domain AMP-binding_C PF13193.6 ABK72877.1 - 4.5e-13 50.0 0.7 3.2e-12 47.2 0.1 3.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 ABK72877.1 - 6.2e-10 39.3 0.8 6.2e-10 39.3 0.8 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site PucR PF07905.11 ABK72878.1 - 7.8e-21 74.5 0.0 1.8e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 Purine catabolism regulatory protein-like family HTH_30 PF13556.6 ABK72878.1 - 1.5e-16 59.9 0.3 3.1e-16 58.9 0.3 1.6 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain NAD_binding_2 PF03446.15 ABK72880.1 - 2.8e-48 164.1 0.9 3.7e-48 163.7 0.9 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ABK72880.1 - 1.8e-36 125.1 0.1 3.1e-36 124.3 0.1 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 ABK72880.1 - 1.3e-11 44.9 0.1 3.6e-11 43.5 0.0 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 ABK72880.1 - 3.9e-05 23.1 0.0 5.4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 ABK72880.1 - 0.0001 21.9 0.2 0.00031 20.3 0.0 1.8 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain PDH PF02153.17 ABK72880.1 - 0.00012 21.2 0.1 0.00016 20.7 0.1 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase 3HCDH_N PF02737.18 ABK72880.1 - 0.00036 20.5 0.4 0.0043 17.0 0.1 2.2 1 1 1 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 ABK72880.1 - 0.00088 18.9 0.1 0.0074 15.9 0.0 2.0 1 1 1 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 ABK72880.1 - 0.016 14.9 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Rossmann-like PF10727.9 ABK72880.1 - 0.024 14.5 0.2 0.055 13.3 0.2 1.6 1 0 0 1 1 1 0 Rossmann-like domain Mur_ligase PF01225.25 ABK72880.1 - 0.072 13.4 0.1 0.16 12.3 0.1 1.6 1 0 0 1 1 1 0 Mur ligase family, catalytic domain ADH_N PF08240.12 ABK72883.1 - 1.3e-27 95.8 2.0 2.4e-27 95.0 2.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ABK72883.1 - 3.6e-21 75.5 0.4 6e-21 74.8 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ABK72883.1 - 3.8e-09 37.7 0.0 8.5e-09 36.6 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 ABK72883.1 - 0.078 12.9 1.3 0.12 12.2 1.3 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Putative_PNPOx PF01243.20 ABK72884.1 - 1.5e-17 63.5 0.0 1.9e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 ABK72884.1 - 0.0005 20.1 0.0 0.0005 20.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase LysR_substrate PF03466.20 ABK72885.1 - 9.9e-27 93.7 3.9 9.9e-27 93.7 3.9 1.9 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 ABK72885.1 - 7.5e-14 51.4 3.0 4.8e-13 48.8 2.8 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_23 PF13384.6 ABK72885.1 - 0.0035 17.1 0.0 0.025 14.4 0.1 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_5 PF01022.20 ABK72885.1 - 0.0057 16.5 0.2 0.013 15.3 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HemN_C PF06969.16 ABK72885.1 - 0.0066 16.5 0.3 0.021 14.9 0.1 2.0 2 0 0 2 2 2 1 HemN C-terminal domain DUF2694 PF10904.8 ABK72886.1 - 0.0062 16.6 0.0 0.0089 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2694) YbaB_DNA_bd PF02575.16 ABK72886.1 - 0.009 16.2 0.0 0.014 15.6 0.0 1.2 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family cobW PF02492.19 ABK72887.1 - 1.9e-34 118.8 0.0 2.4e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 ABK72887.1 - 0.0018 18.2 0.1 0.0018 18.2 0.1 2.0 2 1 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.12 ABK72887.1 - 0.0094 15.2 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin MeaB PF03308.16 ABK72887.1 - 0.0095 14.9 0.0 0.031 13.3 0.0 1.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 ABK72887.1 - 0.019 14.4 0.0 0.24 10.8 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family GTP_EFTU PF00009.27 ABK72887.1 - 0.043 13.4 0.1 0.094 12.2 0.1 1.6 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 ABK72887.1 - 0.045 14.1 0.0 0.059 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 ABK72887.1 - 0.046 13.6 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 NTPase Viral_helicase1 PF01443.18 ABK72887.1 - 0.075 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 ABK72887.1 - 0.12 12.7 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain SelP_N PF04592.14 ABK72887.1 - 2.8 7.3 6.8 4.1 6.7 6.8 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region HMA PF00403.26 ABK72888.1 - 4e-16 59.2 0.3 4.8e-16 59.0 0.3 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Pro_Al_protease PF02983.14 ABK72888.1 - 0.38 10.8 3.8 0.081 13.0 0.8 1.4 2 0 0 2 2 2 0 Alpha-lytic protease prodomain AAA_5 PF07728.14 ABK72889.1 - 7.7e-32 110.2 0.0 1.1e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) CbbQ_C PF08406.10 ABK72889.1 - 1.5e-27 95.7 2.0 3e-27 94.7 2.0 1.5 1 0 0 1 1 1 1 CbbQ/NirQ/NorQ C-terminal AAA_16 PF13191.6 ABK72889.1 - 5.3e-05 23.7 0.0 0.00011 22.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 ABK72889.1 - 5.9e-05 23.5 0.0 9.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 ABK72889.1 - 0.00038 19.9 0.0 0.22 10.9 0.0 2.1 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 ABK72889.1 - 0.0017 18.2 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 ABK72889.1 - 0.0028 17.2 0.0 0.0043 16.6 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region TsaE PF02367.17 ABK72889.1 - 0.0028 17.7 0.0 0.0062 16.5 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 ABK72889.1 - 0.0045 17.3 0.0 0.0084 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 ABK72889.1 - 0.0076 16.0 0.0 0.015 15.0 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 ABK72889.1 - 0.013 15.2 0.0 0.048 13.4 0.0 1.8 2 1 0 2 2 2 0 Sigma-54 interaction domain Rad17 PF03215.15 ABK72889.1 - 0.015 15.2 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain RNA_helicase PF00910.22 ABK72889.1 - 0.018 15.4 0.0 0.029 14.8 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_6 PF12774.7 ABK72889.1 - 0.02 13.9 0.0 0.069 12.1 0.0 1.7 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region T2SSE PF00437.20 ABK72889.1 - 0.026 13.6 0.0 0.049 12.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 ABK72889.1 - 0.031 14.4 0.0 0.056 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ABK72889.1 - 0.046 13.6 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 ABK72889.1 - 0.059 13.4 0.0 0.099 12.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 ABK72889.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 ABK72889.1 - 0.17 11.6 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_35 PF14516.6 ABK72889.1 - 0.21 10.4 0.0 0.3 9.9 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_11 PF13086.6 ABK72889.1 - 0.22 11.3 0.0 0.31 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF2236 PF09995.9 ABK72890.1 - 1.7e-43 149.5 1.1 2.3e-43 149.0 1.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF3087 PF11286.8 ABK72890.1 - 0.036 13.5 0.3 0.061 12.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) Pro-rich PF15240.6 ABK72891.1 - 0.12 12.6 8.3 0.17 12.2 8.3 1.1 1 0 0 1 1 1 0 Proline-rich Trans_reg_C PF00486.28 ABK72892.1 - 3e-29 100.9 0.1 1.3e-28 98.9 0.0 1.9 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 ABK72892.1 - 7.4e-27 93.7 0.0 1.1e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain ALAD PF00490.21 ABK72892.1 - 0.068 12.3 0.0 2.7 7.1 0.0 2.1 2 0 0 2 2 2 0 Delta-aminolevulinic acid dehydratase Pribosyltran_N PF13793.6 ABK72893.1 - 4.8e-44 149.0 0.0 7.7e-44 148.4 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 ABK72893.1 - 6e-23 81.8 0.1 2.1e-22 80.1 0.0 1.9 2 1 1 3 3 3 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 ABK72893.1 - 3.7e-18 65.5 0.1 1.4e-17 63.6 0.1 2.0 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 ABK72893.1 - 3e-05 23.5 0.0 4.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase FUR PF01475.19 ABK72894.1 - 2.9e-35 121.0 0.0 3.3e-35 120.8 0.0 1.0 1 0 0 1 1 1 1 Ferric uptake regulator family HTH_12 PF08461.10 ABK72894.1 - 0.0006 19.7 0.0 0.00093 19.1 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain HTH_32 PF13565.6 ABK72894.1 - 0.0027 18.3 0.1 0.006 17.2 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_20 PF12840.7 ABK72894.1 - 0.025 14.6 0.5 0.04 14.0 0.5 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Arg_repressor PF01316.21 ABK72894.1 - 0.055 13.2 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain Peptidase_C23 PF05379.11 ABK72894.1 - 0.073 13.2 0.2 3.4 7.8 0.1 2.2 2 0 0 2 2 2 0 Carlavirus endopeptidase PadR PF03551.14 ABK72894.1 - 0.092 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family TrmB PF01978.19 ABK72894.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.5 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Abhydrolase_6 PF12697.7 ABK72895.1 - 1.3e-15 58.7 7.1 1.4e-15 58.5 7.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK72895.1 - 2.4e-08 33.5 0.0 5.4e-08 32.4 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ABK72895.1 - 2.7e-06 27.2 0.0 3.7e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 ABK72895.1 - 0.00011 22.0 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 ABK72895.1 - 0.003 17.5 0.0 0.0036 17.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 ABK72895.1 - 0.014 15.1 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein LIDHydrolase PF10230.9 ABK72895.1 - 0.019 14.5 0.0 0.024 14.2 0.0 1.1 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 ABK72895.1 - 0.022 14.6 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase DUF3530 PF12048.8 ABK72895.1 - 0.022 14.2 0.0 0.046 13.1 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3530) Palm_thioest PF02089.15 ABK72895.1 - 0.16 11.8 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF676 PF05057.14 ABK72895.1 - 0.16 11.4 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_3 PF01764.25 ABK72895.1 - 0.16 11.8 0.5 0.34 10.8 0.5 1.5 1 1 0 1 1 1 0 Lipase (class 3) DUF5321 PF17254.2 ABK72895.1 - 0.17 11.3 0.5 0.38 10.2 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5321) Phage_Arf PF17585.2 ABK72895.1 - 0.21 11.6 0.1 0.67 10.0 0.0 1.8 2 0 0 2 2 2 0 Accessory recombination function protein adh_short PF00106.25 ABK72896.1 - 5.4e-33 114.1 0.2 7.6e-33 113.6 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK72896.1 - 6e-28 98.0 0.6 1.2e-27 97.0 0.6 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK72896.1 - 7.1e-09 35.8 0.8 1e-08 35.3 0.8 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 ABK72896.1 - 0.19 10.7 0.1 0.32 10.0 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DFP PF04127.15 ABK72896.1 - 0.38 10.5 2.9 1.8 8.4 2.9 2.0 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein BON PF04972.17 ABK72896.1 - 1.5 9.2 7.4 3.2 8.1 7.4 1.5 1 0 0 1 1 1 0 BON domain Mycobact_memb PF05423.13 ABK72897.1 - 3.8e-61 205.1 0.0 4.4e-61 204.8 0.0 1.0 1 0 0 1 1 1 1 Mycobacterium membrane protein Peptidase_C92 PF05708.12 ABK72898.1 - 0.0032 17.6 0.0 0.071 13.2 0.0 2.2 2 1 0 2 2 2 1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family Amidohydro_2 PF04909.14 ABK72899.1 - 6.8e-27 95.0 3.0 8.5e-27 94.7 3.0 1.0 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.11 ABK72900.1 - 3.1e-28 99.5 10.4 1.5e-26 94.0 10.4 2.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 ABK72900.1 - 2e-17 63.5 0.5 1.6e-07 31.0 0.6 2.8 2 1 0 2 2 2 2 Amidohydrolase family DUF883 PF05957.13 ABK72900.1 - 6.9 7.3 6.3 22 5.7 0.1 3.6 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) T7SS_ESX_EspC PF10824.8 ABK72901.1 - 7e-34 116.3 3.5 7.5e-34 116.2 3.5 1.0 1 0 0 1 1 1 1 Excreted virulence factor EspC, type VII ESX diderm MS_channel PF00924.18 ABK72902.1 - 2e-41 141.8 0.0 2.7e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel CrgA PF06781.12 ABK72902.1 - 0.09 12.8 0.6 0.48 10.5 0.1 2.2 2 0 0 2 2 2 0 Cell division protein CrgA MT0933_antitox PF14013.6 ABK72904.1 - 4.9e-21 74.8 11.4 5.6e-21 74.6 11.4 1.1 1 0 0 1 1 1 1 MT0933-like antitoxin protein ATP_bind_2 PF03668.15 ABK72905.1 - 3.7e-124 413.6 0.0 4.1e-124 413.5 0.0 1.0 1 0 0 1 1 1 1 P-loop ATPase protein family AAA_18 PF13238.6 ABK72905.1 - 0.0067 17.0 0.4 0.15 12.6 0.4 2.4 1 1 0 1 1 1 1 AAA domain Cation_efflux PF01545.21 ABK72906.1 - 1.7e-37 129.1 19.2 2e-37 128.9 19.2 1.1 1 0 0 1 1 1 1 Cation efflux family FtsK_4TM PF13491.6 ABK72906.1 - 0.012 15.3 4.7 0.012 15.3 4.7 2.5 2 1 0 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE ACT_7 PF13840.6 ABK72906.1 - 0.068 13.0 0.3 0.88 9.4 0.2 2.5 2 0 0 2 2 2 0 ACT domain Presenilin PF01080.17 ABK72906.1 - 1.5 7.5 6.9 0.14 10.9 1.5 1.9 2 0 0 2 2 2 0 Presenilin CTP_transf_1 PF01148.20 ABK72907.1 - 2.6e-58 197.9 17.1 3.1e-58 197.6 17.1 1.0 1 0 0 1 1 1 1 Cytidylyltransferase family DUF4342 PF14242.6 ABK72907.1 - 0.0065 16.4 2.7 0.0065 16.4 2.7 3.9 4 1 1 5 5 5 1 Domain of unknown function (DUF4342) BPD_transp_2 PF02653.16 ABK72908.1 - 1.4e-43 149.0 37.9 1.6e-43 148.8 37.9 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component NDUF_B12 PF08122.12 ABK72908.1 - 2.2 8.4 7.8 1.3 9.1 0.3 3.5 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family DUF1358 PF07096.11 ABK72908.1 - 3.5 7.6 5.4 1.1 9.3 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1358) adh_short_C2 PF13561.6 ABK72909.1 - 1.3e-64 217.9 1.9 1.7e-64 217.6 1.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK72909.1 - 4.8e-58 195.9 0.6 6.4e-58 195.4 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK72909.1 - 1.2e-10 41.6 0.8 2.1e-10 40.8 0.8 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK72909.1 - 0.11 11.9 0.2 0.59 9.6 0.1 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family CDC73_C PF05179.14 ABK72909.1 - 0.11 12.1 0.2 0.29 10.8 0.2 1.6 1 1 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family, C-terminal 3HCDH_N PF02737.18 ABK72909.1 - 0.22 11.4 1.0 1.3 8.8 0.1 2.5 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DeoRC PF00455.22 ABK72910.1 - 3.6e-44 150.5 0.0 5.1e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 ABK72910.1 - 2.2e-13 49.7 0.2 4.6e-13 48.7 0.2 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 ABK72910.1 - 2.7e-07 30.4 0.0 2e-06 27.6 0.1 2.1 2 0 0 2 2 2 1 HTH domain GntR PF00392.21 ABK72910.1 - 1.3e-05 24.8 0.0 2.5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 ABK72910.1 - 0.012 15.7 0.2 0.039 14.0 0.2 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 ABK72910.1 - 0.041 13.4 0.0 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 ABK72910.1 - 0.043 13.6 1.6 2.2 8.2 0.0 2.6 3 0 0 3 3 3 0 Homeodomain-like domain HTH_10 PF04967.12 ABK72910.1 - 0.045 13.6 0.0 0.099 12.5 0.0 1.6 1 0 0 1 1 1 0 HTH DNA binding domain MarR PF01047.22 ABK72910.1 - 0.095 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 MarR family Mga PF05043.13 ABK72910.1 - 0.16 12.6 0.0 0.27 11.8 0.0 1.3 1 0 0 1 1 1 0 Mga helix-turn-helix domain Ribosomal_L27A PF00828.19 ABK72911.1 - 1.2e-33 116.5 3.6 1.6e-33 116.1 3.6 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A GerE PF00196.19 ABK72912.1 - 1.4e-10 40.6 0.0 2.1e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family PAS_4 PF08448.10 ABK72912.1 - 1.2e-07 32.0 2.0 2.9e-07 30.7 0.4 2.5 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.7 ABK72912.1 - 0.00066 19.6 0.0 0.0018 18.2 0.0 1.8 2 0 0 2 2 2 1 PAS domain Sigma70_r4_2 PF08281.12 ABK72912.1 - 0.002 17.8 0.4 0.0045 16.6 0.0 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_20 PF12840.7 ABK72912.1 - 0.0043 17.1 1.2 0.52 10.4 0.2 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 ABK72912.1 - 0.0073 16.1 0.1 0.018 14.8 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain PAS PF00989.25 ABK72912.1 - 0.051 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 PAS fold HTH_29 PF13551.6 ABK72912.1 - 0.053 13.5 0.0 0.2 11.7 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn helix DUF501 PF04417.12 ABK72913.1 - 1.8e-34 118.5 0.9 1.4e-32 112.4 0.1 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF501) DivIC PF04977.15 ABK72913.1 - 1.5e-18 66.3 2.3 2.7e-18 65.5 0.0 2.2 2 0 0 2 2 2 1 Septum formation initiator BBS2_C PF14782.6 ABK72913.1 - 0.027 13.2 0.0 0.039 12.7 0.0 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal PASTA PF03793.19 ABK72913.1 - 0.034 14.0 0.1 0.092 12.6 0.1 1.7 1 0 0 1 1 1 0 PASTA domain MHC2-interact PF09307.10 ABK72913.1 - 0.16 12.0 2.5 0.33 10.9 2.5 1.5 1 0 0 1 1 1 0 CLIP, MHC2 interacting DUF3292 PF11696.8 ABK72913.1 - 0.16 10.3 2.6 0.25 9.7 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DUF2730 PF10805.8 ABK72913.1 - 0.16 12.0 0.1 0.29 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) TetR_C_20 PF17925.1 ABK72913.1 - 3.7 7.9 7.8 0.19 12.1 0.7 2.5 2 2 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF3619 PF12279.8 ABK72913.1 - 6.8 7.0 9.0 2.3 8.5 5.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) MlaD PF02470.20 ABK72914.1 - 2.7e-14 53.2 0.2 4.2e-14 52.6 0.2 1.3 1 0 0 1 1 1 1 MlaD protein MbtH PF03621.13 ABK72915.1 - 8.2e-31 105.2 0.1 1e-30 105.0 0.1 1.1 1 0 0 1 1 1 1 MbtH-like protein Acyl-CoA_dh_1 PF00441.24 ABK72916.1 - 2.8e-34 118.5 3.0 4e-34 118.0 3.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK72916.1 - 6.9e-25 87.1 0.0 1.4e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ABK72916.1 - 8.7e-11 42.2 3.1 8.7e-11 42.2 3.1 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain YDG PF18657.1 ABK72916.1 - 0.018 15.2 0.6 0.61 10.3 0.0 2.5 2 0 0 2 2 2 0 YDG domain UbiA PF01040.18 ABK72917.1 - 2.7e-32 112.1 28.1 4e-32 111.5 28.1 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family TetR_N PF00440.23 ABK72918.1 - 1.1e-13 50.7 0.0 2.2e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_13 PF16925.5 ABK72918.1 - 7e-05 22.7 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_6 PF13977.6 ABK72918.1 - 0.067 13.4 0.2 0.31 11.3 0.0 2.1 2 0 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal TetR_N PF00440.23 ABK72919.1 - 5.7e-12 45.2 0.1 5.7e-12 45.2 0.1 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_23 PF13384.6 ABK72919.1 - 0.17 11.7 0.7 1.2 9.0 0.1 2.5 2 1 0 2 2 2 0 Homeodomain-like domain AP_endonuc_2 PF01261.24 ABK72920.1 - 1.3e-25 90.1 0.1 2e-25 89.5 0.1 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF4532 PF15046.6 ABK72921.1 - 0.0014 17.9 0.0 0.0017 17.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4532) SnoaL_2 PF12680.7 ABK72922.1 - 3.9e-16 59.6 0.6 4.6e-16 59.3 0.6 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 ABK72922.1 - 1.8e-07 31.0 0.1 3.3e-07 30.1 0.1 1.4 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DUF4440 PF14534.6 ABK72922.1 - 4.7e-06 27.0 0.0 5.4e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 ABK72922.1 - 9.9e-06 25.8 0.1 2.2e-05 24.7 0.1 1.5 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 ABK72922.1 - 0.033 14.3 0.1 0.043 14.0 0.1 1.4 1 1 0 1 1 1 0 SnoaL-like domain AAA_22 PF13401.6 ABK72923.1 - 0.001 19.3 0.0 0.017 15.4 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ABK72923.1 - 0.0018 18.7 0.0 0.0018 18.7 0.0 3.4 4 0 0 4 4 4 1 AAA ATPase domain Sigma54_activ_2 PF14532.6 ABK72923.1 - 0.063 13.4 0.0 9 6.4 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain GFO_IDH_MocA PF01408.22 ABK72924.1 - 1.1e-15 58.5 0.0 2.4e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 ABK72924.1 - 0.0083 16.7 0.0 0.024 15.2 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF3566 PF12089.8 ABK72925.1 - 2.9e-40 137.3 8.0 3.5e-40 137.0 8.0 1.1 1 0 0 1 1 1 1 Transmembrane domain of unknown function (DUF3566) DUF2189 PF09955.9 ABK72925.1 - 0.14 12.4 5.3 0.16 12.2 4.6 1.4 1 1 0 1 1 1 0 Predicted integral membrane protein (DUF2189) TetR_N PF00440.23 ABK72926.1 - 4.1e-11 42.5 0.0 7.8e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_1 PF00126.27 ABK72927.1 - 7.2e-20 70.7 0.0 2.7e-19 68.8 0.0 2.1 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 ABK72927.1 - 1.2e-09 37.8 4.4 4.3e-09 36.0 4.4 1.8 1 1 0 1 1 1 1 LysR substrate binding domain TMEM238 PF15125.6 ABK72928.1 - 0.019 15.1 0.4 0.019 15.1 0.4 2.2 3 0 0 3 3 3 0 TMEM238 protein family FeS_assembly_P PF01883.19 ABK72929.1 - 4.3e-17 62.0 0.2 8.4e-17 61.1 0.2 1.4 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein bPH_6 PF10756.9 ABK72931.1 - 4.3e-19 68.4 2.2 6.1e-19 67.9 2.2 1.2 1 0 0 1 1 1 1 Bacterial PH domain DUF4191 PF13829.6 ABK72931.1 - 0.022 14.1 0.1 0.024 14.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Lentiviral_Tat PF02998.14 ABK72932.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Lentiviral Tat protein DUF1810 PF08837.11 ABK72933.1 - 6.3e-56 187.9 0.0 7.1e-56 187.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1810) Esterase PF00756.20 ABK72934.1 - 1.8e-13 50.8 0.1 2.6e-13 50.2 0.1 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 ABK72934.1 - 0.0012 18.3 0.2 0.0021 17.6 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 ABK72934.1 - 0.051 12.5 0.0 0.27 10.1 0.0 2.0 3 0 0 3 3 3 0 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 ABK72934.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ABK72934.1 - 0.14 11.4 0.0 0.38 10.0 0.0 1.7 1 1 0 1 1 1 0 Serine aminopeptidase, S33 DUF4131 PF13567.6 ABK72934.1 - 4.5 6.9 19.6 1.4 8.5 3.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Fer2 PF00111.27 ABK72935.1 - 1.6e-12 47.2 0.9 2.6e-12 46.5 0.9 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.21 ABK72935.1 - 5.4e-09 36.7 0.1 2.1e-05 25.1 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain Fer2_4 PF13510.6 ABK72935.1 - 0.00061 19.8 0.1 0.082 13.0 0.1 2.7 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_6 PF08030.12 ABK72935.1 - 0.002 18.3 0.0 0.61 10.2 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain GMC_oxred_N PF00732.19 ABK72936.1 - 1.6e-67 228.0 0.0 1.9e-67 227.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ABK72936.1 - 7.5e-07 29.8 0.0 1.3e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 ABK72936.1 - 0.046 13.3 0.8 0.046 13.3 0.8 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase TrkA_N PF02254.18 ABK72936.1 - 0.065 13.5 0.1 0.14 12.4 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_8 PF13450.6 ABK72936.1 - 0.087 13.1 2.8 0.11 12.8 1.3 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ABK72936.1 - 0.34 9.9 5.2 2.9 6.9 0.2 2.1 2 0 0 2 2 2 0 FAD binding domain DUF1177 PF06675.11 ABK72937.1 - 0.26 10.1 2.5 0.12 11.2 0.6 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1177) Sigma70_r2 PF04542.14 ABK72938.1 - 4.8e-17 61.5 1.7 4.8e-17 61.5 1.7 1.7 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 ABK72938.1 - 3.1e-15 55.6 0.0 5.8e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 ABK72938.1 - 1.2e-11 43.9 0.0 2.9e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 ABK72938.1 - 0.0045 16.9 0.2 0.0088 15.9 0.2 1.6 1 1 0 1 1 1 1 ECF sigma factor HTH_28 PF13518.6 ABK72938.1 - 0.018 15.2 0.0 0.039 14.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain DUF134 PF02001.16 ABK72938.1 - 0.055 14.0 0.0 0.092 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF134 ADH_zinc_N_2 PF13602.6 ABK72940.1 - 4.7e-16 60.0 0.1 1.2e-15 58.7 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ABK72940.1 - 4.4e-15 55.8 0.1 7.1e-15 55.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ABK72940.1 - 2.3e-09 37.1 0.0 7.6e-08 32.2 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.19 ABK72940.1 - 0.041 13.2 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain LDcluster4 PF18306.1 ABK72940.1 - 0.058 13.0 0.4 0.096 12.3 0.4 1.4 1 0 0 1 1 1 0 SLOG cluster4 family ELFV_dehydrog PF00208.21 ABK72940.1 - 0.073 12.8 0.2 0.11 12.1 0.2 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Epimerase PF01370.21 ABK72940.1 - 0.18 11.3 0.2 0.25 10.8 0.2 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 ABK72941.1 - 2.3e-44 151.2 0.1 2.8e-44 150.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK72941.1 - 1.8e-38 132.4 0.8 2.3e-38 132.1 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK72941.1 - 3.6e-11 43.3 0.8 6.1e-11 42.6 0.1 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 ABK72941.1 - 7.6e-07 29.2 0.4 1.1e-06 28.7 0.4 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ABK72941.1 - 6.5e-06 25.8 0.1 8.4e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_Gly3P_dh_N PF01210.23 ABK72941.1 - 0.019 15.0 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF1776 PF08643.10 ABK72941.1 - 0.064 12.6 0.0 0.089 12.1 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 ABK72941.1 - 0.14 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 ABK72941.1 - 0.23 11.3 1.3 0.55 10.1 1.2 1.7 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.13 ABK72941.1 - 0.32 10.5 2.6 1.5 8.3 1.0 2.1 2 0 0 2 2 2 0 NmrA-like family Bac_luciferase PF00296.20 ABK72942.1 - 1.1e-42 146.5 10.2 3.9e-42 144.8 10.2 1.7 1 1 0 1 1 1 1 Luciferase-like monooxygenase Putative_PNPOx PF01243.20 ABK72943.1 - 2.5e-13 50.0 0.0 3.3e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase BPD_transp_1 PF00528.22 ABK72944.1 - 2.3e-19 69.9 10.8 2.3e-19 69.9 10.8 2.0 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Nucleoside_tran PF01733.18 ABK72944.1 - 0.079 12.3 5.0 0.093 12.1 1.4 2.2 1 1 0 2 2 2 0 Nucleoside transporter Hydrolase_4 PF12146.8 ABK72946.1 - 1.9e-14 53.5 0.6 1.3e-13 50.8 0.4 2.3 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ABK72946.1 - 1.6e-13 51.8 13.9 2e-13 51.5 13.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ABK72946.1 - 9.3e-13 48.4 0.7 8.3e-12 45.3 0.7 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ABK72946.1 - 0.00092 18.7 0.2 0.0081 15.7 0.1 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 ABK72946.1 - 0.0057 16.2 0.0 0.012 15.2 0.0 1.5 2 0 0 2 2 2 1 Dienelactone hydrolase family MFS_1 PF07690.16 ABK72947.1 - 1e-30 106.9 76.2 1.2e-23 83.6 41.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK72947.1 - 1.7e-25 89.8 22.3 2.1e-19 69.7 5.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 ABK72947.1 - 1.1e-06 27.5 14.4 1.1e-06 27.5 14.4 1.6 1 1 0 1 1 1 1 MFS/sugar transport protein FlgT_C PF16538.5 ABK72948.1 - 0.00026 21.4 0.0 0.00059 20.3 0.0 1.6 2 0 0 2 2 2 1 Flagellar assembly protein T, C-terminal domain SUFU PF05076.13 ABK72949.1 - 1.3e-32 113.2 0.0 1.5e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 Suppressor of fused protein (SUFU) DUF1547 PF07577.11 ABK72949.1 - 0.027 14.9 0.0 0.046 14.1 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1547) TPP_enzyme_N PF02776.18 ABK72950.1 - 2.2e-31 108.8 0.5 5.7e-31 107.4 0.2 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 ABK72950.1 - 4.1e-19 68.9 0.1 1.2e-17 64.2 0.1 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 ABK72950.1 - 1.3e-10 41.2 0.3 8.4e-10 38.5 0.1 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain E1_dh PF00676.20 ABK72950.1 - 0.083 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component RraA-like PF03737.15 ABK72951.1 - 5.8e-37 127.2 2.4 7.4e-37 126.8 2.4 1.1 1 0 0 1 1 1 1 Aldolase/RraA RDD PF06271.12 ABK72952.1 - 1.9e-16 60.6 6.1 2.5e-16 60.2 6.1 1.2 1 0 0 1 1 1 1 RDD family Phage_holin_1 PF04531.13 ABK72952.1 - 0.092 13.3 1.9 0.16 12.5 1.9 1.3 1 0 0 1 1 1 0 Bacteriophage holin TMEM169 PF15052.6 ABK72952.1 - 0.23 11.6 2.3 0.36 11.0 2.3 1.2 1 0 0 1 1 1 0 TMEM169 protein family RseC_MucC PF04246.12 ABK72952.1 - 1.4 8.9 3.5 2.1 8.3 3.5 1.2 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC FUSC_2 PF13515.6 ABK72953.1 - 2.1e-19 69.9 16.0 2.1e-19 69.9 16.0 2.9 2 1 0 2 2 2 1 Fusaric acid resistance protein-like PE-PPE PF08237.11 ABK72954.1 - 1.7e-69 233.8 0.0 3.2e-69 232.9 0.0 1.4 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.16 ABK72954.1 - 0.16 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase NAD_binding_2 PF03446.15 ABK72955.1 - 2.2e-38 131.9 0.1 3.1e-38 131.4 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ABK72955.1 - 2.1e-21 76.4 0.1 3.6e-21 75.7 0.1 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 ABK72955.1 - 6.4e-06 25.6 0.0 1.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 ABK72955.1 - 3.6e-05 24.3 0.0 9.8e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 ABK72955.1 - 0.00025 21.1 0.0 0.00044 20.3 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 ABK72955.1 - 0.0057 16.9 0.0 0.033 14.4 0.0 2.1 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 ABK72955.1 - 0.035 13.7 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 ABK72955.1 - 0.064 13.1 0.0 0.16 11.8 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zinc_ribbon_15 PF17032.5 ABK72956.1 - 1e-08 35.8 0.2 1.2e-08 35.6 0.2 1.1 1 0 0 1 1 1 1 zinc-ribbon family Zn_Tnp_IS1595 PF12760.7 ABK72956.1 - 0.0011 18.9 1.9 0.02 14.9 0.2 2.1 2 0 0 2 2 2 1 Transposase zinc-ribbon domain RecR PF02132.15 ABK72956.1 - 0.0063 16.0 1.5 0.17 11.5 0.1 2.1 2 0 0 2 2 2 1 RecR protein zf-CCCH_6 PF18585.1 ABK72956.1 - 0.027 14.3 1.5 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Zn-ribbon_8 PF09723.10 ABK72956.1 - 0.061 13.4 0.1 2.7 8.2 0.0 2.2 2 0 0 2 2 2 0 Zinc ribbon domain Wza_C PF18412.1 ABK72956.1 - 0.4 10.5 2.4 0.76 9.6 2.4 1.4 1 0 0 1 1 1 0 Outer-membrane lipoprotein Wza C-terminal domain NINJA_B PF16136.5 ABK72957.1 - 0.6 10.5 6.7 1.1 9.7 6.7 1.5 1 0 0 1 1 1 0 Putative nuclear localisation signal F-protein PF00469.20 ABK72957.1 - 8.3 5.9 7.7 25 4.4 0.0 2.2 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef Esterase PF00756.20 ABK72958.1 - 1.8e-13 50.8 0.1 2.6e-13 50.2 0.1 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 ABK72958.1 - 0.0012 18.3 0.2 0.0021 17.6 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 ABK72958.1 - 0.051 12.5 0.0 0.27 10.1 0.0 2.0 3 0 0 3 3 3 0 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 ABK72958.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ABK72958.1 - 0.14 11.4 0.0 0.38 10.0 0.0 1.7 1 1 0 1 1 1 0 Serine aminopeptidase, S33 DUF4131 PF13567.6 ABK72958.1 - 4.5 6.9 19.6 1.4 8.5 3.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Ribonucleas_3_3 PF14622.6 ABK72959.1 - 8.3e-35 119.7 0.0 1.2e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 ABK72959.1 - 6.6e-20 71.7 0.0 1.3e-19 70.7 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 ABK72959.1 - 1.5e-14 54.5 0.0 2.1e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 ABK72959.1 - 0.0044 17.2 0.0 0.0084 16.3 0.0 1.4 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 YbaB_DNA_bd PF02575.16 ABK72960.1 - 0.0084 16.3 0.8 0.01 16.0 0.8 1.2 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family TatD_DNase PF01026.21 ABK72961.1 - 4.1e-64 216.4 0.0 4.7e-64 216.2 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_1 PF01979.20 ABK72961.1 - 0.01 15.2 0.2 0.018 14.4 0.2 1.4 1 1 0 1 1 1 1 Amidohydrolase family ABC_tran PF00005.27 ABK72962.1 - 1.9e-32 112.7 0.0 3.4e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK72962.1 - 4.1e-09 36.7 1.2 1.9e-06 28.0 0.1 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system NIL PF09383.10 ABK72962.1 - 9.9e-08 31.7 0.0 2.4e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 NIL domain SMC_N PF02463.19 ABK72962.1 - 2.6e-05 23.8 0.0 0.011 15.1 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ABK72962.1 - 0.00021 21.6 0.3 0.0076 16.5 0.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ABK72962.1 - 0.00025 21.5 1.9 0.0006 20.2 1.8 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 ABK72962.1 - 0.0014 18.3 0.0 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 ABK72962.1 - 0.0065 16.6 0.3 0.013 15.6 0.3 1.7 1 1 0 1 1 1 1 AAA domain G-alpha PF00503.20 ABK72962.1 - 0.019 14.2 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_25 PF13481.6 ABK72962.1 - 0.022 14.3 0.4 0.5 9.9 0.4 2.4 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 ABK72962.1 - 0.028 14.4 1.6 0.24 11.3 0.1 2.6 2 1 1 3 3 3 0 NACHT domain RsgA_GTPase PF03193.16 ABK72962.1 - 0.042 13.8 0.1 0.086 12.7 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase DUF87 PF01935.17 ABK72962.1 - 0.051 13.7 0.1 0.095 12.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain ABC_ATPase PF09818.9 ABK72962.1 - 0.053 12.3 1.6 7.9 5.1 0.1 2.8 2 1 0 2 2 2 0 Predicted ATPase of the ABC class NB-ARC PF00931.22 ABK72962.1 - 0.069 12.3 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain APS_kinase PF01583.20 ABK72962.1 - 0.07 13.0 0.4 0.63 9.9 0.1 2.5 2 1 1 3 3 3 0 Adenylylsulphate kinase cobW PF02492.19 ABK72962.1 - 0.082 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 ABK72962.1 - 0.15 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.21 ABK72962.1 - 0.16 11.3 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.23 ABK72962.1 - 0.3 11.2 0.9 0.88 9.7 0.8 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_13 PF13166.6 ABK72962.1 - 0.32 9.6 0.1 7.8 5.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Peripla_BP_6 PF13458.6 ABK72964.1 - 1.1e-67 229.1 0.3 1.3e-67 228.9 0.3 1.0 1 0 0 1 1 1 1 Periplasmic binding protein Peripla_BP_5 PF13433.6 ABK72964.1 - 6.5e-45 153.7 0.0 7.9e-45 153.4 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Fer4 PF00037.27 ABK72965.1 - 9.4e-11 41.1 17.2 1.4e-08 34.2 5.7 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 ABK72965.1 - 5.8e-06 27.2 5.0 0.00038 21.3 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 ABK72965.1 - 9.6e-06 26.1 12.9 4e-05 24.1 13.0 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 ABK72965.1 - 0.00016 21.6 4.9 0.00016 21.6 4.9 2.5 2 1 0 2 2 2 1 4Fe-4S binding domain Fer4_4 PF12800.7 ABK72965.1 - 0.00021 21.5 1.6 0.00021 21.5 1.6 2.5 3 0 0 3 3 2 1 4Fe-4S binding domain Fer4_9 PF13187.6 ABK72965.1 - 0.00036 20.6 10.2 0.00091 19.4 10.2 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 ABK72965.1 - 0.00042 20.4 1.6 0.00042 20.4 1.6 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 ABK72965.1 - 0.0013 18.7 3.7 0.0013 18.7 3.7 2.9 2 1 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.6 ABK72965.1 - 0.0038 17.3 15.0 0.023 14.8 15.0 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 ABK72965.1 - 0.0048 17.3 1.8 0.0048 17.3 1.8 2.2 1 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 ABK72965.1 - 0.0063 17.0 11.8 0.033 14.7 2.1 2.2 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 ABK72965.1 - 0.017 15.7 6.7 0.13 12.8 1.3 2.4 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 ABK72965.1 - 0.21 12.6 17.9 0.27 12.3 7.1 2.8 2 1 0 2 2 2 0 4Fe-4S binding domain HTH_1 PF00126.27 ABK72966.1 - 2e-16 59.7 0.8 4.4e-16 58.6 0.8 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 ABK72966.1 - 5.5e-13 48.8 3.1 2.2e-12 46.8 3.1 1.9 1 1 0 1 1 1 1 LysR substrate binding domain HTH_30 PF13556.6 ABK72966.1 - 0.00051 19.8 0.2 0.002 17.9 0.2 2.0 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_24 PF13412.6 ABK72966.1 - 0.0023 17.4 0.1 0.0049 16.4 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 ABK72966.1 - 0.012 15.5 0.2 0.029 14.2 0.2 1.7 1 0 0 1 1 1 0 MarR family P22_Cro PF14549.6 ABK72966.1 - 0.013 15.3 0.1 0.026 14.3 0.1 1.5 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro HTH_11 PF08279.12 ABK72966.1 - 0.072 13.1 0.0 0.24 11.4 0.0 1.9 1 0 0 1 1 1 0 HTH domain HTH_28 PF13518.6 ABK72966.1 - 0.072 13.2 0.2 0.26 11.4 0.2 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_50 PF18024.1 ABK72966.1 - 0.12 11.9 0.1 0.27 10.9 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3597 PF12200.8 ABK72967.1 - 9 6.9 9.9 2.3 8.7 1.4 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3597) Abhydrolase_1 PF00561.20 ABK72969.1 - 7.4e-72 242.1 0.0 9.2e-72 241.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 ABK72969.1 - 1.1e-24 86.5 0.1 8.1e-24 83.7 0.0 2.4 3 0 0 3 3 3 1 TAP-like protein Hydrolase_4 PF12146.8 ABK72969.1 - 4.8e-05 22.8 0.0 0.043 13.1 0.0 2.5 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 ABK72969.1 - 0.021 14.7 0.0 0.38 10.6 0.0 2.3 2 0 0 2 2 2 0 Serine hydrolase DUF3500 PF12006.8 ABK72970.1 - 5.7e-95 318.2 0.0 6.6e-95 318.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) p450 PF00067.22 ABK72971.1 - 3.4e-25 88.7 0.1 2e-22 79.6 0.1 2.8 1 1 0 1 1 1 1 Cytochrome P450 Hemerythrin PF01814.23 ABK72973.1 - 8.9e-10 39.3 11.8 8.9e-10 39.3 11.8 1.6 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF615 PF04751.14 ABK72973.1 - 0.027 14.5 2.2 0.027 14.5 2.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF615) SGL PF08450.12 ABK72974.1 - 3.9e-14 52.8 0.0 1.2e-08 34.9 0.0 5.1 2 2 1 3 3 3 3 SMP-30/Gluconolactonase/LRE-like region PQQ_2 PF13360.6 ABK72974.1 - 1.3e-08 34.7 2.3 0.002 17.7 0.0 4.2 3 2 1 4 4 4 3 PQQ-like domain Str_synth PF03088.16 ABK72974.1 - 9.5e-07 28.9 0.0 2.8 8.1 0.0 6.2 5 2 3 8 8 8 2 Strictosidine synthase NHL PF01436.21 ABK72974.1 - 1.8e-06 27.7 10.3 0.089 12.9 0.1 7.2 9 0 0 9 9 9 2 NHL repeat GSDH PF07995.11 ABK72974.1 - 0.057 12.7 0.0 5.2 6.3 0.0 3.5 3 1 0 3 3 3 0 Glucose / Sorbosone dehydrogenase PQQ PF01011.21 ABK72974.1 - 0.85 9.7 3.8 4.3 7.4 0.0 4.1 5 0 0 5 5 5 0 PQQ enzyme repeat Iso_dh PF00180.20 ABK72975.1 - 8.7e-85 284.9 0.0 9.9e-85 284.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Metal_hydrol PF10118.9 ABK72976.1 - 5.2e-69 232.7 1.7 5.9e-69 232.5 1.7 1.0 1 0 0 1 1 1 1 Predicted metal-dependent hydrolase AurF PF11583.8 ABK72976.1 - 3.6e-05 23.2 0.9 0.029 13.7 0.9 2.4 1 1 1 2 2 2 2 P-aminobenzoate N-oxygenase AurF LCM PF04072.14 ABK72977.1 - 5.6e-39 134.0 0.0 7.4e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Ribosomal_L20 PF00453.18 ABK72978.1 - 1.1e-41 141.3 8.7 1.2e-41 141.1 8.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L20 HTH_20 PF12840.7 ABK72979.1 - 7.3e-09 35.6 0.2 3.1e-08 33.6 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_5 PF01022.20 ABK72979.1 - 1.3e-08 34.5 0.0 2.5e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 ABK72979.1 - 3.7e-07 29.6 0.2 7.8e-07 28.6 0.2 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 ABK72979.1 - 1.1e-06 28.4 0.0 2.5e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 HTH domain MarR_2 PF12802.7 ABK72979.1 - 1.1e-05 25.2 1.5 0.00022 21.1 0.5 2.6 2 0 0 2 2 2 1 MarR family Sigma70_r4 PF04545.16 ABK72979.1 - 0.0028 17.1 0.1 0.0078 15.7 0.1 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 TrmB PF01978.19 ABK72979.1 - 0.0074 16.2 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB PadR PF03551.14 ABK72979.1 - 0.011 15.7 0.1 0.023 14.7 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family HTH_28 PF13518.6 ABK72979.1 - 0.012 15.8 0.7 0.012 15.8 0.7 3.6 4 1 1 5 5 5 0 Helix-turn-helix domain MarR PF01047.22 ABK72979.1 - 0.037 14.0 0.0 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 MarR family HTH_DeoR PF08220.12 ABK72979.1 - 0.045 13.5 0.0 0.23 11.2 0.0 2.2 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain HTH_29 PF13551.6 ABK72979.1 - 0.07 13.2 2.1 0.15 12.1 2.1 1.6 1 0 0 1 1 1 0 Winged helix-turn helix POTRA_2 PF08479.11 ABK72979.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 POTRA domain, ShlB-type HTH_AsnC-type PF13404.6 ABK72979.1 - 0.12 12.2 0.4 0.36 10.7 0.4 1.8 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Pyridox_ox_2 PF12900.7 ABK72980.1 - 2.6e-31 108.5 0.0 3.7e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FMN_bind_2 PF04299.12 ABK72980.1 - 0.23 11.2 0.0 0.46 10.2 0.0 1.4 1 1 0 1 1 1 0 Putative FMN-binding domain Amidohydro_2 PF04909.14 ABK72981.1 - 1.4e-32 113.6 0.3 1.7e-32 113.4 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase Iso_dh PF00180.20 ABK72982.1 - 2e-86 290.3 0.0 2.3e-86 290.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF4569 PF15133.6 ABK72982.1 - 0.096 12.4 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) UreF PF01730.16 ABK72983.1 - 1.2e-17 64.8 4.2 1.5e-17 64.4 4.2 1.2 1 0 0 1 1 1 1 UreF AAA PF00004.29 ABK72984.1 - 6.4e-49 165.8 0.1 4.6e-48 163.0 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_OB_N PF17758.1 ABK72984.1 - 6.4e-24 83.4 0.8 1.9e-23 81.8 0.1 2.2 3 0 0 3 3 2 1 Proteasomal ATPase OB N-terminal domain Prot_ATP_ID_OB PF16450.5 ABK72984.1 - 1.5e-19 69.7 0.1 1.6e-17 63.2 0.0 2.8 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 ABK72984.1 - 1e-08 35.8 0.8 1.7e-06 28.5 0.0 3.4 2 1 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 ABK72984.1 - 6.5e-06 25.6 0.0 1.2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_2 PF07724.14 ABK72984.1 - 1e-05 25.8 0.0 2.5e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 ABK72984.1 - 5.6e-05 23.3 0.0 0.00015 21.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 ABK72984.1 - 0.00025 21.4 0.0 0.0007 20.0 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 ABK72984.1 - 0.00038 20.7 0.0 0.0018 18.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 ABK72984.1 - 0.00069 19.6 0.0 0.0021 18.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 ABK72984.1 - 0.00087 19.1 0.0 0.0025 17.6 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 ABK72984.1 - 0.0025 17.8 0.0 0.046 13.6 0.0 2.4 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 ABK72984.1 - 0.0027 17.1 0.0 0.0067 15.8 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 ABK72984.1 - 0.0039 17.1 0.0 0.13 12.2 0.0 2.3 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_lid_3 PF17862.1 ABK72984.1 - 0.0041 16.9 0.6 0.87 9.4 0.0 2.9 2 0 0 2 2 2 1 AAA+ lid domain AAA_18 PF13238.6 ABK72984.1 - 0.0052 17.3 0.0 0.027 15.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 ABK72984.1 - 0.0056 16.7 0.0 0.016 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 ABK72984.1 - 0.011 15.0 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain ABC_tran PF00005.27 ABK72984.1 - 0.012 16.1 0.0 0.067 13.7 0.0 2.2 2 2 0 2 2 1 0 ABC transporter FliJ PF02050.16 ABK72984.1 - 0.022 15.0 0.3 0.047 13.9 0.3 1.5 1 0 0 1 1 1 0 Flagellar FliJ protein IstB_IS21 PF01695.17 ABK72984.1 - 0.024 14.4 0.0 0.058 13.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 ABK72984.1 - 0.028 13.9 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Golgin_A5 PF09787.9 ABK72984.1 - 0.03 13.8 0.1 0.053 13.0 0.1 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 AAA_25 PF13481.6 ABK72984.1 - 0.037 13.6 0.0 0.13 11.9 0.0 1.9 2 0 0 2 2 1 0 AAA domain DUF815 PF05673.13 ABK72984.1 - 0.073 12.2 0.0 0.33 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 ABK72984.1 - 0.081 12.8 0.0 0.26 11.2 0.0 1.9 1 0 0 1 1 1 0 NTPase AAA_23 PF13476.6 ABK72984.1 - 0.095 13.2 0.9 0.29 11.6 0.0 2.2 3 0 0 3 3 1 0 AAA domain AAA_19 PF13245.6 ABK72984.1 - 0.095 13.0 0.2 1.7 8.9 0.0 2.5 2 1 0 2 2 2 0 AAA domain VWA PF00092.28 ABK72984.1 - 0.11 12.8 0.1 0.44 10.8 0.0 1.9 2 0 0 2 2 2 0 von Willebrand factor type A domain ZapB PF06005.12 ABK72984.1 - 0.11 12.9 1.3 0.79 10.2 0.1 2.6 2 0 0 2 2 2 0 Cell division protein ZapB NACHT PF05729.12 ABK72984.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 ABK72984.1 - 0.14 11.9 0.0 0.4 10.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain JAKMIP_CC3 PF16034.5 ABK72984.1 - 0.14 12.1 0.5 0.26 11.2 0.5 1.4 1 0 0 1 1 1 0 JAKMIP CC3 domain NB-ARC PF00931.22 ABK72984.1 - 0.15 11.2 0.0 0.32 10.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activ_2 PF14532.6 ABK72984.1 - 0.17 12.0 0.0 1 9.5 0.0 2.3 3 0 0 3 3 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 ABK72984.1 - 0.19 10.8 0.0 0.38 9.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 HSCB_C PF07743.13 ABK72984.1 - 0.73 10.4 5.1 0.58 10.7 2.2 2.5 2 1 1 3 3 1 0 HSCB C-terminal oligomerisation domain bZIP_1 PF00170.21 ABK72984.1 - 0.75 9.9 3.2 0.65 10.1 0.4 2.3 2 0 0 2 2 2 0 bZIP transcription factor Nnf1 PF03980.14 ABK72984.1 - 1.4 9.3 6.3 6.7 7.1 3.1 3.0 2 1 0 2 2 2 0 Nnf1 DUF465 PF04325.13 ABK72984.1 - 5.7 7.1 6.7 13 5.9 4.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF465) His_Phos_1 PF00300.22 ABK72985.1 - 1.3e-37 129.4 0.3 1.5e-37 129.2 0.3 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Sigma70_r2 PF04542.14 ABK72986.1 - 1.6e-09 37.3 1.2 5.4e-09 35.7 1.2 1.9 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 ABK72986.1 - 4.4e-09 35.9 0.1 1.2e-08 34.5 0.1 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 ABK72986.1 - 0.0059 16.1 0.4 0.027 14.0 0.1 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_psq PF05225.16 ABK72986.1 - 0.43 10.3 3.2 0.31 10.8 0.2 2.4 2 0 0 2 2 2 0 helix-turn-helix, Psq domain HTH_23 PF13384.6 ABK72986.1 - 1.2 9.0 4.4 0.34 10.7 0.3 2.4 2 0 0 2 2 2 0 Homeodomain-like domain Oxidored_q2 PF00420.24 ABK72987.1 - 1.9e-24 85.3 2.6 2.4e-24 85.0 2.6 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Bac_GDH PF05088.12 ABK72988.1 - 0 1829.8 0.0 0 1829.5 0.0 1.0 1 0 0 1 1 1 1 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog PF00208.21 ABK72988.1 - 0.17 11.6 0.0 0.67 9.6 0.0 2.0 2 1 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase RunxI PF08504.11 ABK72988.1 - 0.19 12.4 0.0 0.56 10.9 0.0 1.8 1 0 0 1 1 1 0 Runx inhibition domain PE PF00934.20 ABK72989.1 - 2.2e-22 79.2 12.5 2.8e-22 78.8 12.5 1.1 1 0 0 1 1 1 1 PE family GMP_synt_C PF00958.22 ABK72990.1 - 1.3e-39 134.2 0.0 2.9e-39 133.0 0.0 1.7 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 ABK72990.1 - 1.6e-39 135.7 0.0 2.2e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 ABK72990.1 - 1.4e-09 37.5 0.1 5.6e-06 25.7 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 ABK72990.1 - 1.9e-09 37.6 0.0 7.7e-09 35.6 0.0 2.1 1 1 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 ABK72990.1 - 0.0017 17.2 0.1 0.0032 16.3 0.1 1.4 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.21 ABK72990.1 - 0.0019 18.0 0.3 0.0034 17.1 0.3 1.4 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.13 ABK72990.1 - 0.0026 17.3 0.0 0.04 13.4 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ThiI PF02568.14 ABK72990.1 - 0.012 15.3 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) DJ-1_PfpI PF01965.24 ABK72990.1 - 0.023 14.5 0.1 0.62 9.9 0.0 2.4 2 0 0 2 2 2 0 DJ-1/PfpI family ATP_bind_3 PF01171.20 ABK72990.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 PP-loop family Bac_luciferase PF00296.20 ABK72991.1 - 5.8e-62 209.9 2.5 7.1e-62 209.6 2.5 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase adh_short PF00106.25 ABK72992.1 - 8.4e-48 162.4 1.0 1.4e-47 161.7 1.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK72992.1 - 1.4e-37 129.5 2.4 1.8e-37 129.2 2.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK72992.1 - 2.2e-12 47.3 1.1 4.7e-12 46.2 1.1 1.5 1 0 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 ABK72992.1 - 0.0055 17.4 0.4 0.017 15.8 0.3 1.8 1 1 0 1 1 1 1 Methyltransferase domain 3HCDH_N PF02737.18 ABK72992.1 - 0.032 14.1 0.7 0.062 13.2 0.7 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SWIRM-assoc_3 PF16498.5 ABK72992.1 - 0.11 12.8 0.8 13 6.1 0.1 2.8 3 0 0 3 3 3 0 SWIRM-associated domain at the C-terminal AA_permease_2 PF13520.6 ABK72993.1 - 2e-27 96.1 35.2 2.9e-27 95.6 35.2 1.1 1 0 0 1 1 1 1 Amino acid permease K_trans PF02705.16 ABK72993.1 - 0.005 15.4 23.9 0.0081 14.7 1.2 3.1 3 1 1 4 4 4 2 K+ potassium transporter WSS_VP PF12175.8 ABK72993.1 - 0.097 12.1 0.4 0.22 10.9 0.4 1.6 1 0 0 1 1 1 0 White spot syndrome virus structural envelope protein VP DUF3921 PF13060.6 ABK72993.1 - 0.16 12.0 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) 4HBT PF03061.22 ABK72994.1 - 8.3e-09 35.7 0.0 1.5e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily PS-DH PF14765.6 ABK72994.1 - 0.06 12.6 0.0 0.082 12.1 0.0 1.2 1 0 0 1 1 1 0 Polyketide synthase dehydratase DUF3565 PF12088.8 ABK72994.1 - 0.22 11.5 0.2 0.5 10.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3565) HTH_AsnC-type PF13404.6 ABK72995.1 - 5.2e-15 55.0 0.2 1.1e-14 54.0 0.2 1.6 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain AsnC_trans_reg PF01037.21 ABK72995.1 - 5.3e-14 51.9 0.1 8.6e-14 51.3 0.1 1.4 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 ABK72995.1 - 6.6e-09 35.2 0.0 1.2e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 ABK72995.1 - 0.0008 18.9 0.1 0.0012 18.3 0.1 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 NapD PF03927.13 ABK72995.1 - 0.0032 17.5 0.1 0.0073 16.3 0.1 1.6 1 0 0 1 1 1 1 NapD protein HTH_11 PF08279.12 ABK72995.1 - 0.014 15.3 0.1 0.055 13.4 0.0 2.0 2 0 0 2 2 2 0 HTH domain PaaX PF07848.12 ABK72995.1 - 0.027 14.7 0.9 0.095 12.9 0.2 2.1 2 0 0 2 2 2 0 PaaX-like protein MarR_2 PF12802.7 ABK72995.1 - 0.039 13.9 0.5 0.11 12.5 0.3 1.8 2 1 0 2 2 2 0 MarR family Sigma70_r4_2 PF08281.12 ABK72995.1 - 0.045 13.4 0.1 0.081 12.6 0.1 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 NHase_alpha PF02979.16 ABK72996.1 - 6.3e-72 240.8 0.0 7.5e-72 240.5 0.0 1.0 1 0 0 1 1 1 1 Nitrile hydratase, alpha chain Frankia_peptide PF14407.6 ABK72996.1 - 0.012 15.6 0.1 0.048 13.6 0.0 1.9 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. SnoaL_4 PF13577.6 ABK72997.1 - 4.6e-26 91.4 0.0 5.1e-26 91.3 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like domain Scytalone_dh PF02982.14 ABK72997.1 - 0.007 16.2 0.1 0.0093 15.8 0.1 1.3 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_2 PF12680.7 ABK72997.1 - 0.0071 17.0 0.2 0.011 16.4 0.2 1.4 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 ABK72997.1 - 0.11 12.7 0.3 1.2 9.4 0.0 2.1 2 0 0 2 2 2 0 SnoaL-like domain ESX-1_EspG PF14011.6 ABK72998.1 - 2.2e-62 210.9 12.3 2.5e-62 210.7 12.3 1.0 1 0 0 1 1 1 1 EspG family Clp_N PF02861.20 ABK72999.1 - 8.4e-16 57.8 10.2 5.7e-09 36.0 1.7 3.3 3 0 0 3 3 3 3 Clp amino terminal domain, pathogenicity island component DUF2371 PF10177.9 ABK73000.1 - 0.08 13.1 0.0 0.082 13.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) RuvX PF03652.15 ABK73002.1 - 1e-41 142.5 0.4 1.2e-41 142.3 0.4 1.0 1 0 0 1 1 1 1 Holliday junction resolvase PRiA4_ORF3 PF07929.11 ABK73003.1 - 2.1e-51 174.1 0.0 2.5e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein Polyketide_cyc2 PF10604.9 ABK73004.1 - 9.6e-08 32.4 0.6 1.8e-07 31.5 0.6 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 ABK73004.1 - 0.0018 18.5 0.1 0.0023 18.2 0.1 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein BPD_transp_1 PF00528.22 ABK73005.1 - 2.1e-16 60.2 16.3 2.1e-16 60.2 16.3 2.2 1 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component MMPL PF03176.15 ABK73006.1 - 6.7e-216 715.6 24.1 3e-112 374.8 8.4 2.4 2 0 0 2 2 2 2 MMPL family Aminotran_3 PF00202.21 ABK73007.1 - 1.6e-133 445.3 0.0 1.8e-133 445.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 ABK73007.1 - 0.093 11.9 0.0 1.5 7.9 0.0 2.3 2 1 0 2 2 2 0 Aminotransferase class I and II Zincin_2 PF10103.9 ABK73008.1 - 5.5e-107 357.9 1.5 6.2e-107 357.7 1.5 1.0 1 0 0 1 1 1 1 Zincin-like metallopeptidase AAA_3 PF07726.11 ABK73009.1 - 8.9e-59 197.0 0.1 1.6e-58 196.3 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 ABK73009.1 - 1.6e-18 66.3 4.1 1.6e-18 66.3 4.1 1.9 2 0 0 2 2 2 1 AAA lid domain AAA_5 PF07728.14 ABK73009.1 - 2.8e-13 50.0 0.0 6e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.23 ABK73009.1 - 3e-07 29.8 0.1 4.7e-06 25.9 0.1 2.1 1 1 0 1 1 1 1 MCM P-loop domain AAA PF00004.29 ABK73009.1 - 7.8e-07 29.6 0.0 2.4e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 ABK73009.1 - 2.1e-06 27.6 0.1 3.2e-05 23.7 0.1 2.8 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 ABK73009.1 - 2.4e-05 24.1 0.0 3.9e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 ABK73009.1 - 5e-05 22.8 0.4 0.14 11.5 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 ABK73009.1 - 0.062 13.0 0.3 0.61 9.8 0.1 2.5 2 1 0 2 2 2 0 AAA domain Transposase_20 PF02371.16 ABK73009.1 - 0.08 13.3 0.0 0.31 11.4 0.0 2.1 2 0 0 2 2 2 0 Transposase IS116/IS110/IS902 family Isochorismatase PF00857.20 ABK73010.1 - 6.7e-34 117.6 0.1 7.4e-34 117.4 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family HTH_5 PF01022.20 ABK73011.1 - 2.8e-13 49.5 0.1 4.9e-13 48.7 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 ABK73011.1 - 4.1e-09 36.4 0.2 7.7e-09 35.5 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 ABK73011.1 - 9.4e-08 31.8 0.1 1.5e-07 31.2 0.1 1.4 1 1 0 1 1 1 1 MarR family HTH_11 PF08279.12 ABK73011.1 - 1.2e-05 25.1 0.0 1.7e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 HTH domain TrmB PF01978.19 ABK73011.1 - 7.5e-05 22.5 0.0 0.0001 22.1 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 ABK73011.1 - 0.0003 20.7 0.0 0.00045 20.2 0.0 1.4 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_10 PF04967.12 ABK73011.1 - 0.0014 18.4 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 HTH DNA binding domain RP-C PF03428.13 ABK73011.1 - 0.0018 18.0 0.1 0.003 17.2 0.1 1.3 1 1 0 1 1 1 1 Replication protein C N-terminal domain HTH_36 PF13730.6 ABK73011.1 - 0.0077 16.2 0.0 0.027 14.4 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_IclR PF09339.10 ABK73011.1 - 0.0082 15.9 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR PF01047.22 ABK73011.1 - 0.0091 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 ABK73011.1 - 0.0093 16.3 0.0 0.013 15.8 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator HTH_24 PF13412.6 ABK73011.1 - 0.01 15.4 0.1 0.022 14.3 0.1 1.7 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_38 PF13936.6 ABK73011.1 - 0.021 14.6 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain GntR PF00392.21 ABK73011.1 - 0.023 14.3 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family YdaS_antitoxin PF15943.5 ABK73011.1 - 0.045 13.6 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_3 PF01381.22 ABK73011.1 - 0.052 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix HTH_8 PF02954.19 ABK73011.1 - 0.066 13.0 0.0 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family HTH_28 PF13518.6 ABK73011.1 - 0.075 13.2 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 ABK73011.1 - 0.078 13.0 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix HTH_17 PF12728.7 ABK73011.1 - 0.086 13.0 0.0 0.15 12.2 0.0 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 ABK73011.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.6 1 1 0 1 1 1 0 Homeodomain-like domain Fe_dep_repress PF01325.19 ABK73011.1 - 0.14 12.4 0.0 0.2 11.9 0.0 1.2 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Phage_CI_repr PF07022.13 ABK73011.1 - 0.16 12.1 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain Cupin_2 PF07883.11 ABK73012.1 - 7.4e-12 44.8 0.1 1.2e-11 44.1 0.1 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 ABK73012.1 - 1.4e-08 34.5 0.0 1.9e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 ABK73012.1 - 0.0027 17.4 0.0 0.0044 16.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.12 ABK73012.1 - 0.029 14.1 0.0 0.043 13.6 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ MannoseP_isomer PF01050.18 ABK73012.1 - 0.085 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Cupin_6 PF12852.7 ABK73012.1 - 0.085 12.6 0.1 0.088 12.5 0.1 1.2 1 0 0 1 1 1 0 Cupin ECH_1 PF00378.20 ABK73013.1 - 1.2e-32 113.2 0.0 2e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK73013.1 - 2.8e-20 73.1 0.0 4.4e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase HMGL-like PF00682.19 ABK73014.1 - 1.5e-79 267.3 0.0 4.2e-79 265.8 0.0 1.8 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.10 ABK73014.1 - 1.2e-31 109.4 1.1 2.3e-31 108.4 1.1 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain LUD_dom PF02589.15 ABK73015.1 - 6.4e-23 81.5 0.3 5.3e-21 75.2 0.3 2.1 1 1 0 1 1 1 1 LUD domain HTH_Tnp_1 PF01527.20 ABK73016.1 - 2.5e-07 30.9 4.8 9.9e-07 29.0 4.8 1.8 1 1 0 1 1 1 1 Transposase HTH_28 PF13518.6 ABK73016.1 - 0.0093 16.1 0.2 0.019 15.1 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_17 PF12728.7 ABK73016.1 - 0.023 14.9 0.1 0.057 13.6 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain OMPdecase PF00215.24 ABK73017.1 - 3.1e-40 138.2 0.0 3.8e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family NifU_N PF01592.16 ABK73018.1 - 3.5e-33 114.5 0.1 5.4e-33 113.9 0.1 1.3 1 1 0 1 1 1 1 NifU-like N terminal domain zf-NADH-PPase PF09297.11 ABK73019.1 - 0.064 12.9 3.6 0.17 11.6 3.6 1.7 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Zn_ribbon_recom PF13408.6 ABK73019.1 - 0.14 12.7 1.0 0.26 11.8 1.0 1.5 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain Fer4_22 PF17179.4 ABK73021.1 - 6.1e-32 110.3 10.9 6.1e-32 110.3 10.9 1.7 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 ABK73021.1 - 1.4e-09 38.4 2.6 0.00025 21.5 0.7 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 ABK73021.1 - 7.2e-09 35.8 1.5 0.0006 20.0 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 ABK73021.1 - 1.8e-08 34.9 6.1 0.00084 19.9 0.9 2.6 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 ABK73021.1 - 7.6e-07 29.1 10.3 0.0053 16.8 0.2 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 ABK73021.1 - 5.8e-06 26.7 9.9 0.00016 22.1 11.0 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 ABK73021.1 - 1.8e-05 24.5 12.8 0.022 14.9 2.1 2.8 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 ABK73021.1 - 3.5e-05 23.9 14.0 0.0047 17.1 15.2 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 ABK73021.1 - 4.5e-05 23.5 10.0 0.044 13.9 0.4 2.6 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 ABK73021.1 - 4.6e-05 24.3 9.6 0.039 14.9 0.7 2.5 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4 PF00037.27 ABK73021.1 - 0.0018 18.0 17.0 0.088 12.7 3.5 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_3 PF12798.7 ABK73021.1 - 0.034 15.1 4.1 0.034 15.1 4.1 2.9 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.7 ABK73021.1 - 0.038 14.1 20.9 0.2 11.8 4.5 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 ABK73021.1 - 0.045 14.3 18.0 0.23 12.1 3.5 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain CoA_trans PF01144.23 ABK73022.1 - 9.9e-47 159.1 0.0 2.6e-46 157.8 0.0 1.6 2 0 0 2 2 2 1 Coenzyme A transferase TAP_C PF03943.13 ABK73022.1 - 0.22 11.2 0.2 0.41 10.3 0.2 1.5 1 0 0 1 1 1 0 TAP C-terminal domain Thiolase_N PF00108.23 ABK73024.1 - 1.1e-50 172.4 0.0 1.7e-50 171.8 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ABK73024.1 - 1.5e-38 131.2 0.8 5.1e-38 129.5 0.7 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 ABK73024.1 - 0.059 13.2 1.4 0.081 12.8 0.0 1.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 ABK73024.1 - 0.3 10.6 5.2 0.14 11.7 0.6 2.4 3 0 0 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain DUF4333 PF14230.6 ABK73025.1 - 2.7e-14 53.2 1.4 4.1e-14 52.6 1.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4333) AMP-binding PF00501.28 ABK73027.1 - 1.2e-76 258.0 0.0 1.5e-76 257.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK73027.1 - 3.2e-23 82.5 0.9 8.1e-23 81.2 0.9 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MlaD PF02470.20 ABK73028.1 - 4.8e-16 58.8 0.3 8.4e-16 58.1 0.3 1.4 1 0 0 1 1 1 1 MlaD protein Mce4_CUP1 PF11887.8 ABK73028.1 - 0.0019 17.7 10.1 0.0055 16.2 9.6 2.0 1 1 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative Dor1 PF04124.12 ABK73028.1 - 0.016 13.9 2.0 0.023 13.4 2.0 1.2 1 0 0 1 1 1 0 Dor1-like family DUF948 PF06103.11 ABK73028.1 - 0.031 14.5 6.4 0.084 13.1 1.4 3.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Apolipoprotein PF01442.18 ABK73028.1 - 0.11 12.3 5.0 0.25 11.2 4.8 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4201 PF13870.6 ABK73028.1 - 0.18 11.5 1.2 0.44 10.3 1.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) SlyX PF04102.12 ABK73028.1 - 0.36 11.5 1.9 4.2 8.1 0.0 2.9 1 1 2 3 3 3 0 SlyX FlgN PF05130.12 ABK73028.1 - 0.46 11.0 2.9 0.83 10.2 2.9 1.4 1 0 0 1 1 1 0 FlgN protein Baculo_PEP_C PF04513.12 ABK73028.1 - 1.7 8.7 10.8 14 5.8 5.3 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus UPF0184 PF03670.13 ABK73028.1 - 3.8 8.0 5.0 5.6 7.4 0.1 2.8 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) PDDEXK_1 PF12705.7 ABK73029.1 - 4.9e-39 134.8 0.0 1.5e-38 133.2 0.0 1.7 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily UvrD-helicase PF00580.21 ABK73029.1 - 5.3e-25 88.6 0.0 8.2e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 ABK73029.1 - 1.3e-12 48.3 0.0 3.6e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C PF13361.6 ABK73029.1 - 2.3e-11 43.7 0.0 1.2e-10 41.4 0.0 1.9 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 ABK73029.1 - 0.032 14.5 0.1 0.92 9.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 ABK73029.1 - 0.095 11.9 0.0 0.67 9.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.6 ABK73029.1 - 4.9 7.1 5.3 28 4.6 0.2 2.7 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Glyco_hydro_30C PF17189.4 ABK73030.1 - 0.041 14.1 0.0 0.075 13.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 30 beta sandwich domain SBP_bac_6 PF13343.6 ABK73031.1 - 6e-24 84.8 1.4 9.2e-24 84.2 1.4 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 ABK73031.1 - 2.6e-22 80.0 8.6 3.3e-22 79.6 7.9 1.5 1 1 1 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 ABK73031.1 - 7e-08 32.8 6.5 1.2e-07 32.0 6.5 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 ABK73031.1 - 1.4e-05 24.9 0.3 5.6e-05 23.0 0.1 2.0 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein TAT_signal PF10518.9 ABK73031.1 - 0.0021 17.8 13.5 0.0055 16.5 13.5 1.8 1 1 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence dCache_1 PF02743.18 ABK73032.1 - 8e-07 29.1 0.0 8.4e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Cache domain CMD PF02627.20 ABK73033.1 - 2.6e-17 62.7 2.2 2.6e-17 62.7 2.2 2.0 2 1 0 2 2 2 1 Carboxymuconolactone decarboxylase family Ubie_methyltran PF01209.18 ABK73034.1 - 1.2e-57 194.9 0.0 1.5e-57 194.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 ABK73034.1 - 2.1e-17 63.6 0.1 3.9e-17 62.7 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABK73034.1 - 1.2e-14 54.7 0.1 2.5e-14 53.8 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABK73034.1 - 3.6e-09 36.6 0.0 7e-09 35.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABK73034.1 - 1.3e-08 34.9 0.0 2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK73034.1 - 5.6e-05 23.8 0.0 0.00011 22.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 ABK73034.1 - 0.0018 18.2 0.0 0.0026 17.6 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Pyridox_ox_2 PF12900.7 ABK73035.1 - 6.6e-28 97.5 0.5 7.7e-28 97.3 0.5 1.0 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 ABK73035.1 - 0.062 13.5 0.3 0.13 12.5 0.2 1.5 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase FYRN PF05964.14 ABK73035.1 - 0.19 11.6 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 F/Y-rich N-terminus CCDC73 PF15818.5 ABK73035.1 - 0.34 8.7 0.0 0.39 8.5 0.0 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 73 family PseudoU_synth_2 PF00849.22 ABK73036.1 - 1.4e-19 70.7 0.0 2.2e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 ABK73036.1 - 2.2e-13 49.7 0.5 6e-13 48.3 0.5 1.8 1 0 0 1 1 1 1 S4 domain MFS_1 PF07690.16 ABK73037.1 - 0.016 14.1 0.2 0.016 14.1 0.2 2.5 3 0 0 3 3 3 0 Major Facilitator Superfamily CENP-B_N PF04218.13 ABK73037.1 - 0.047 13.3 0.0 0.13 11.9 0.0 1.8 1 1 0 1 1 1 0 CENP-B N-terminal DNA-binding domain GWT1 PF06423.12 ABK73037.1 - 0.076 13.1 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 GWT1 4HB_MCP_1 PF12729.7 ABK73037.1 - 0.52 9.8 6.0 0.49 9.9 3.0 2.4 2 1 0 2 2 2 0 Four helix bundle sensory module for signal transduction RXLR PF16810.5 ABK73037.1 - 2.9 8.3 4.9 31 5.0 0.5 2.7 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity Wzy_C PF04932.15 ABK73037.1 - 5.9 6.5 7.5 2.1 8.0 1.7 2.7 2 1 0 3 3 3 0 O-Antigen ligase DUF5518 PF17647.1 ABK73037.1 - 7.9 6.7 12.1 0.066 13.4 0.8 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5518) Acylphosphatase PF00708.18 ABK73038.1 - 2.1e-24 85.7 0.0 2.3e-24 85.6 0.0 1.0 1 0 0 1 1 1 1 Acylphosphatase PK PF00224.21 ABK73039.1 - 5.1e-122 407.1 3.4 6.6e-122 406.7 3.4 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 ABK73039.1 - 4.1e-25 88.3 0.0 2.6e-24 85.7 0.0 2.3 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain IMPDH PF00478.25 ABK73039.1 - 0.043 12.8 0.2 0.27 10.2 0.0 2.2 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain PcrB PF01884.17 ABK73039.1 - 0.2 11.1 1.3 0.85 9.0 0.1 2.6 2 1 0 3 3 3 0 PcrB family Aminotran_1_2 PF00155.21 ABK73040.1 - 4.8e-53 180.6 0.0 6.1e-53 180.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 ABK73040.1 - 0.026 13.4 0.0 0.031 13.1 0.0 1.1 1 0 0 1 1 1 0 Allinase HTH_23 PF13384.6 ABK73041.1 - 6.7e-07 28.9 1.4 1.1e-06 28.2 1.4 1.4 1 1 0 1 1 1 1 Homeodomain-like domain HTH_AsnC-type PF13404.6 ABK73041.1 - 1.3e-05 24.9 0.8 0.00088 19.1 0.1 2.3 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain Sigma70_r4_2 PF08281.12 ABK73041.1 - 0.00014 21.4 0.1 0.00035 20.2 0.1 1.7 1 1 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 ABK73041.1 - 0.0015 18.0 0.1 0.006 16.1 0.1 1.8 1 1 1 2 2 2 1 Sigma-70, region 4 HTH_11 PF08279.12 ABK73041.1 - 0.0025 17.7 0.0 0.0047 16.8 0.0 1.5 1 1 1 2 2 2 1 HTH domain HTH_3 PF01381.22 ABK73041.1 - 0.0073 16.3 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix Terminase_5 PF06056.12 ABK73041.1 - 0.015 15.1 0.2 0.028 14.3 0.2 1.4 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Sigma70_ECF PF07638.11 ABK73041.1 - 0.018 14.9 0.0 0.019 14.9 0.0 1.0 1 0 0 1 1 1 0 ECF sigma factor HTH_28 PF13518.6 ABK73041.1 - 0.019 15.1 1.2 0.04 14.0 0.4 1.8 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_30 PF13556.6 ABK73041.1 - 0.02 14.7 0.1 0.05 13.4 0.0 1.6 1 1 1 2 2 2 0 PucR C-terminal helix-turn-helix domain HTH_38 PF13936.6 ABK73041.1 - 0.024 14.4 0.1 0.04 13.7 0.1 1.4 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 ABK73041.1 - 0.029 14.4 0.5 0.1 12.6 0.1 1.9 1 1 1 2 2 2 0 Winged helix-turn helix HTH_AraC PF00165.23 ABK73041.1 - 0.052 13.7 0.0 0.079 13.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family P22_Cro PF14549.6 ABK73041.1 - 0.075 12.9 0.2 0.12 12.2 0.2 1.3 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro HTH_7 PF02796.15 ABK73041.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain of resolvase Crp PF00325.20 ABK73041.1 - 0.23 11.1 1.0 0.72 9.6 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family HTH_31 PF13560.6 ABK73041.1 - 1.5 9.2 8.2 1.6 9.1 6.7 1.8 1 1 1 2 2 2 0 Helix-turn-helix domain DUF4320 PF14208.6 ABK73042.1 - 0.065 13.3 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4320) DA1-like PF12315.8 ABK73042.1 - 0.068 12.5 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein DA1 CN_hydrolase PF00795.22 ABK73043.1 - 7.9e-31 107.3 0.0 1e-30 107.0 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF4899 PF16240.5 ABK73043.1 - 0.24 10.6 0.0 0.34 10.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4899) adh_short PF00106.25 ABK73044.1 - 2.1e-56 190.5 2.0 2.6e-56 190.2 2.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK73044.1 - 1.7e-46 158.7 5.1 2.1e-46 158.4 5.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK73044.1 - 4e-15 56.2 0.8 5.8e-15 55.7 0.8 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK73044.1 - 1.9e-09 37.3 1.4 1.9e-09 37.3 1.4 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ABK73044.1 - 0.00088 18.8 0.2 0.0022 17.4 0.1 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 ABK73044.1 - 0.01 14.9 1.0 0.01 14.9 1.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain Thiolase_N PF00108.23 ABK73045.1 - 7.1e-60 202.6 0.4 1.3e-59 201.7 0.4 1.4 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ABK73045.1 - 1.1e-45 154.3 0.3 1.8e-45 153.5 0.3 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 ABK73045.1 - 0.026 14.4 0.1 1.3 8.9 0.2 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 ABK73045.1 - 0.031 13.9 3.2 0.049 13.2 0.8 2.4 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 ABK73045.1 - 2.5 8.2 5.9 17 5.4 0.3 3.8 3 1 1 4 4 4 0 Beta-ketoacyl synthase, C-terminal domain TetR_N PF00440.23 ABK73047.1 - 5.9e-15 54.8 0.2 1.6e-14 53.4 0.2 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family LacI PF00356.21 ABK73047.1 - 0.00054 19.7 1.0 0.031 14.1 0.0 3.0 3 0 0 3 3 3 1 Bacterial regulatory proteins, lacI family TrbI PF03743.14 ABK73047.1 - 0.018 14.8 0.0 2.7 7.8 0.0 2.1 1 1 1 2 2 2 0 Bacterial conjugation TrbI-like protein HTH_Tnp_ISL3 PF13542.6 ABK73047.1 - 0.049 13.0 0.0 0.14 11.5 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 TetR_C_21 PF17926.1 ABK73047.1 - 0.097 12.8 0.5 0.25 11.5 0.0 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TetR_C_29 PF17938.1 ABK73047.1 - 0.17 12.0 0.0 0.43 10.7 0.0 1.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF1488 PF07369.11 ABK73047.1 - 0.21 11.6 1.7 9.8 6.2 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1488) Methyltransf_11 PF08241.12 ABK73048.1 - 2.5e-23 82.6 0.0 7.1e-23 81.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABK73048.1 - 3.1e-20 72.7 0.1 1.5e-19 70.5 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABK73048.1 - 1.1e-16 61.0 0.0 2.1e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABK73048.1 - 3.3e-13 49.8 0.0 7.7e-13 48.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK73048.1 - 5.4e-13 49.5 0.1 1.5e-12 48.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 ABK73048.1 - 7.8e-12 45.0 0.0 1.4e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 ABK73048.1 - 3e-06 27.0 0.0 5.1e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) MetW PF07021.12 ABK73048.1 - 0.00076 19.1 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.15 ABK73048.1 - 0.0019 18.1 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_29 PF03141.16 ABK73048.1 - 0.0077 14.8 0.0 0.011 14.3 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 ABK73048.1 - 0.023 14.2 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 ABK73048.1 - 0.038 13.4 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FCD PF07729.12 ABK73050.1 - 6.8e-21 75.0 11.0 1.3e-20 74.1 11.0 1.4 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 ABK73050.1 - 3e-20 71.6 2.5 8.4e-20 70.2 0.2 2.4 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_11 PF08279.12 ABK73050.1 - 0.025 14.5 0.1 0.068 13.1 0.1 1.8 1 0 0 1 1 1 0 HTH domain TFIIE_alpha PF02002.17 ABK73050.1 - 0.058 13.3 0.1 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 TFIIE alpha subunit HTH_5 PF01022.20 ABK73050.1 - 0.065 13.1 0.4 0.24 11.3 0.2 2.0 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Fe_dep_repress PF01325.19 ABK73050.1 - 0.11 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Rrf2 PF02082.20 ABK73050.1 - 0.12 12.8 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator TrmB PF01978.19 ABK73050.1 - 0.16 11.9 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.7 ABK73050.1 - 0.23 11.5 2.8 0.39 10.8 0.3 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain KH_5 PF13184.6 ABK73051.1 - 4.1e-26 90.9 0.1 1.7e-25 88.9 0.1 2.1 2 0 0 2 2 2 1 NusA-like KH domain NusA_N PF08529.11 ABK73051.1 - 3.6e-19 69.3 0.1 1.9e-09 37.9 0.0 2.9 2 1 1 3 3 3 2 NusA N-terminal domain KH_1 PF00013.29 ABK73051.1 - 0.0002 21.1 0.0 0.14 12.0 0.0 2.7 2 0 0 2 2 2 2 KH domain S1 PF00575.23 ABK73051.1 - 0.0077 16.6 0.2 0.021 15.1 0.2 1.8 1 0 0 1 1 1 1 S1 RNA binding domain KH_2 PF07650.17 ABK73051.1 - 0.015 15.1 1.0 0.55 10.1 0.0 3.0 3 0 0 3 3 3 0 KH domain ABC_tran PF00005.27 ABK73052.1 - 1.4e-31 109.9 0.0 2e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 ABK73052.1 - 3.9e-09 36.5 2.6 1.3e-08 34.9 1.3 2.3 2 0 0 2 2 2 1 TOBE domain AAA_21 PF13304.6 ABK73052.1 - 0.00012 22.0 0.0 0.0057 16.5 0.0 2.1 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 ABK73052.1 - 0.0004 20.4 0.0 0.00051 20.0 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain OB_MalK PF17912.1 ABK73052.1 - 0.0005 20.9 0.0 0.0024 18.7 0.0 2.3 1 0 0 1 1 1 1 MalK OB fold domain RsgA_GTPase PF03193.16 ABK73052.1 - 0.00062 19.7 0.0 0.0014 18.5 0.0 1.5 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 ABK73052.1 - 0.00076 19.8 0.0 0.0012 19.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 ABK73052.1 - 0.0013 18.2 0.0 0.43 10.0 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ABK73052.1 - 0.0062 16.9 0.0 0.0087 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 ABK73052.1 - 0.022 14.5 0.0 0.029 14.1 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 ABK73052.1 - 0.025 14.7 1.4 0.12 12.6 1.4 2.1 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ABK73052.1 - 0.029 13.9 0.2 0.18 11.4 0.0 2.2 2 1 1 3 3 3 0 AAA domain TOBE PF03459.17 ABK73052.1 - 0.032 14.5 2.0 0.053 13.8 1.3 1.8 2 0 0 2 2 2 0 TOBE domain AAA_29 PF13555.6 ABK73052.1 - 0.032 14.0 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 ABK73052.1 - 0.064 13.5 0.4 0.16 12.2 0.2 1.8 1 1 1 2 2 2 0 AAA domain AAA PF00004.29 ABK73052.1 - 0.082 13.3 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ribosomal_S17 PF00366.20 ABK73052.1 - 0.1 12.7 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein S17 AAA_5 PF07728.14 ABK73052.1 - 0.16 12.0 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 ABK73052.1 - 0.19 12.1 0.0 0.4 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF1772 PF08592.11 ABK73053.1 - 0.059 13.7 7.1 0.27 11.6 0.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Abhydrolase_1 PF00561.20 ABK73054.1 - 5.4e-22 78.7 0.1 6.6e-22 78.4 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK73054.1 - 5e-20 73.1 16.2 7e-20 72.6 16.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK73054.1 - 2.5e-09 36.8 0.4 2.3e-08 33.6 0.4 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 ABK73054.1 - 0.0031 17.3 0.2 0.014 15.1 0.3 1.8 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_4 PF08386.10 ABK73054.1 - 0.0063 16.6 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_2 PF02230.16 ABK73054.1 - 0.25 11.1 0.0 3 7.6 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase MASE2 PF05230.11 ABK73055.1 - 0.0062 16.6 1.6 0.0062 16.6 1.6 2.4 2 0 0 2 2 2 1 MASE2 domain DUF3169 PF11368.8 ABK73055.1 - 0.023 14.2 0.4 0.032 13.7 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3169) Tmemb_185A PF10269.9 ABK73055.1 - 0.062 13.0 3.6 0.25 11.0 3.7 1.6 1 1 0 1 1 1 0 Transmembrane Fragile-X-F protein Peptidase_M48 PF01435.18 ABK73055.1 - 0.57 9.9 1.7 1 9.1 0.1 1.8 2 0 0 2 2 2 0 Peptidase family M48 MFS_1 PF07690.16 ABK73056.1 - 3e-29 102.1 84.4 1.4e-24 86.7 42.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK73056.1 - 1.7e-23 83.2 35.9 3.7e-21 75.5 35.9 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter DUF3464 PF11947.8 ABK73056.1 - 0.76 9.5 1.9 2.1 8.1 0.1 2.5 1 1 1 2 2 2 0 Photosynthesis affected mutant 68 Phos_pyr_kin PF08543.12 ABK73057.1 - 1.3e-64 218.0 0.2 1.5e-64 217.7 0.2 1.0 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 ABK73057.1 - 2.6e-10 40.1 1.4 3.6e-10 39.6 1.4 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.17 ABK73057.1 - 0.0024 17.4 2.2 0.0097 15.4 2.2 1.9 1 1 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 ABK73057.1 - 0.029 13.8 0.1 0.052 12.9 0.1 1.4 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family DUF2207 PF09972.9 ABK73058.1 - 1.2e-73 248.6 0.0 1.7e-73 248.1 0.0 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) SRAP PF02586.14 ABK73059.1 - 1e-62 211.6 0.0 1.1e-62 211.4 0.0 1.0 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Zn_peptidase PF04228.13 ABK73060.1 - 1.5e-77 260.9 1.7 1.9e-77 260.6 1.7 1.0 1 0 0 1 1 1 1 Putative neutral zinc metallopeptidase Reprolysin_3 PF13582.6 ABK73060.1 - 0.13 12.7 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Hydrolase_4 PF12146.8 ABK73061.1 - 1.2e-15 57.4 0.4 2e-11 43.6 0.1 2.0 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ABK73061.1 - 1.1e-10 41.6 0.2 1.1e-09 38.3 0.1 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK73061.1 - 1.4e-08 35.6 1.7 2.2e-08 35.0 1.5 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ABK73061.1 - 4.1e-06 26.4 0.0 5.2e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 ABK73061.1 - 9.1e-06 25.4 0.0 0.12 12.0 0.0 2.7 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PAF-AH_p_II PF03403.13 ABK73061.1 - 0.0007 18.2 0.0 0.14 10.7 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Esterase PF00756.20 ABK73061.1 - 0.013 15.1 0.0 0.016 14.8 0.0 1.1 1 0 0 1 1 1 0 Putative esterase Ser_hydrolase PF06821.13 ABK73061.1 - 0.015 15.2 0.2 0.039 13.8 0.2 1.7 1 1 0 1 1 1 0 Serine hydrolase Glyco_trans_4_4 PF13579.6 ABK73061.1 - 0.016 15.7 0.3 0.031 14.7 0.3 1.7 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain PGAP1 PF07819.13 ABK73061.1 - 0.021 14.6 0.0 0.025 14.3 0.0 1.1 1 0 0 1 1 1 0 PGAP1-like protein Acyl_transf_1 PF00698.21 ABK73061.1 - 0.027 14.0 0.2 0.044 13.3 0.2 1.3 1 0 0 1 1 1 0 Acyl transferase domain BAAT_C PF08840.11 ABK73061.1 - 0.072 13.0 0.0 0.12 12.3 0.0 1.3 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 ABK73062.1 - 3.3e-09 36.6 0.0 8.2e-09 35.3 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family Amidohydro_3 PF07969.11 ABK73064.1 - 6e-90 303.0 23.2 7e-90 302.7 23.2 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 ABK73064.1 - 1.1e-07 31.5 0.8 8.3e-05 22.0 0.0 2.6 2 1 0 2 2 2 2 Amidohydrolase family DUF3298 PF11738.8 ABK73065.1 - 5.6e-12 46.5 0.0 9.9e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3298) Phage_integrase PF00589.22 ABK73066.1 - 4.9e-36 124.1 0.0 7.2e-36 123.6 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 ABK73066.1 - 1.2e-12 47.9 0.1 1.7e-11 44.2 0.1 2.6 1 1 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 ABK73066.1 - 8.3e-05 23.0 0.0 0.00059 20.3 0.0 2.2 1 1 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain HxlR PF01638.17 ABK73067.1 - 7.5e-21 73.8 0.0 1.2e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 HxlR-like helix-turn-helix SCP2 PF02036.17 ABK73067.1 - 0.00011 22.7 0.0 0.0002 21.8 0.0 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 ABK73067.1 - 0.00036 20.8 0.0 0.0015 18.8 0.0 1.9 2 0 0 2 2 2 1 Alkyl sulfatase C-terminal HTH_27 PF13463.6 ABK73067.1 - 0.011 16.2 0.1 0.23 12.0 0.0 2.6 2 0 0 2 2 2 0 Winged helix DNA-binding domain PadR PF03551.14 ABK73067.1 - 0.025 14.5 0.0 0.15 12.1 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family Vps23_core PF09454.10 ABK73067.1 - 0.15 12.0 0.0 0.86 9.6 0.0 2.2 2 0 0 2 2 2 0 Vps23 core domain Radical_SAM PF04055.21 ABK73068.1 - 2.1e-25 90.1 0.0 2.9e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily SPASM PF13186.6 ABK73068.1 - 9.1e-06 26.1 0.1 1.8e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 Iron-sulfur cluster-binding domain Fer4_12 PF13353.6 ABK73068.1 - 2.5e-05 24.6 0.0 4.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 ABK73068.1 - 0.00016 21.8 0.0 0.00026 21.1 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain NIR_SIR_ferr PF03460.17 ABK73068.1 - 0.031 14.1 0.1 0.13 12.2 0.0 2.0 2 0 0 2 2 2 0 Nitrite/Sulfite reductase ferredoxin-like half domain DUF4191 PF13829.6 ABK73069.1 - 1.2e-85 286.4 1.8 1.4e-85 286.1 1.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4191) DUF2207 PF09972.9 ABK73069.1 - 0.0029 16.5 0.5 0.0036 16.1 0.5 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) SNARE_assoc PF09335.11 ABK73069.1 - 0.022 15.2 2.2 0.039 14.4 2.2 1.6 1 0 0 1 1 1 0 SNARE associated Golgi protein MRP PF09387.10 ABK73069.1 - 0.045 13.7 0.5 0.063 13.3 0.5 1.2 1 0 0 1 1 1 0 Mitochondrial RNA binding protein MRP RskA PF10099.9 ABK73069.1 - 0.35 11.1 7.4 0.017 15.4 2.2 1.6 2 0 0 2 2 2 0 Anti-sigma-K factor rskA TraG_N PF07916.11 ABK73069.1 - 0.44 9.3 1.5 0.57 9.0 1.5 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region MlaD PF02470.20 ABK73070.1 - 3.8e-11 43.1 0.1 1.4e-10 41.3 0.0 2.0 2 0 0 2 2 2 1 MlaD protein Mce4_CUP1 PF11887.8 ABK73070.1 - 7.1e-06 25.7 1.6 3.4e-05 23.4 1.5 1.9 1 1 1 2 2 2 1 Cholesterol uptake porter CUP1 of Mce4, putative DUF2114 PF09887.9 ABK73070.1 - 0.08 11.4 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) Baculo_PEP_C PF04513.12 ABK73070.1 - 0.089 12.8 0.1 0.78 9.8 0.1 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4148 PF13663.6 ABK73071.1 - 0.25 11.6 2.0 18 5.6 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Mycobact_memb PF05423.13 ABK73072.1 - 8.9e-05 22.4 0.3 8.9e-05 22.4 0.3 1.7 2 0 0 2 2 2 1 Mycobacterium membrane protein FAP PF07174.11 ABK73072.1 - 0.21 11.0 18.5 0.31 10.5 18.5 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) ADH_zinc_N PF00107.26 ABK73073.1 - 2.2e-27 95.6 0.1 4.2e-27 94.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ABK73073.1 - 2.8e-21 76.9 0.6 4.6e-21 76.2 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ABK73073.1 - 1.8e-11 43.9 0.6 1e-10 41.4 0.1 2.3 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 ABK73073.1 - 0.0007 19.1 0.6 0.0012 18.4 0.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase AlaDh_PNT_C PF01262.21 ABK73073.1 - 0.0018 17.6 6.5 0.0018 17.6 6.5 1.5 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ABK73073.1 - 0.033 13.6 0.1 0.3 10.4 0.1 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ACP_syn_III_C PF08541.10 ABK73073.1 - 0.055 13.6 1.9 0.11 12.7 0.4 2.3 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Eno-Rase_NADH_b PF12242.8 ABK73073.1 - 0.099 12.4 1.0 0.19 11.5 1.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ADH_N_2 PF16884.5 ABK73073.1 - 0.22 11.4 0.7 0.57 10.1 0.1 2.0 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase Pyr_redox PF00070.27 ABK73073.1 - 2.7 8.6 5.8 1.6 9.4 0.9 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase MlaE PF02405.16 ABK73074.1 - 1.6e-54 184.8 27.2 2.1e-54 184.5 27.2 1.1 1 0 0 1 1 1 1 Permease MlaE KRBA1 PF15287.6 ABK73074.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 KRBA1 family repeat DUF4834 PF16118.5 ABK73075.1 - 0.33 11.9 3.5 0.3 12.1 0.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) Phage_holin_3_6 PF07332.11 ABK73075.1 - 0.58 10.2 6.4 0.91 9.6 6.4 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DciA PF05258.12 ABK73076.1 - 3e-23 82.0 0.6 4.2e-23 81.6 0.6 1.2 1 0 0 1 1 1 1 Dna[CI] antecedent, DciA TetR_N PF00440.23 ABK73077.1 - 5.8e-13 48.4 0.3 1.3e-12 47.2 0.3 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 ABK73077.1 - 0.0058 16.9 2.5 0.0077 16.5 0.0 2.3 2 1 0 3 3 3 1 Tetracyclin repressor-like, C-terminal domain Cutinase PF01083.22 ABK73078.1 - 2.9e-47 160.9 0.6 3.6e-47 160.6 0.6 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_6 PF12697.7 ABK73078.1 - 0.00027 21.6 7.2 0.00034 21.3 7.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 ABK73078.1 - 0.00042 20.2 0.4 0.0024 17.7 0.1 2.0 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase DUF2974 PF11187.8 ABK73078.1 - 0.16 11.5 0.4 0.25 10.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF2064 PF09837.9 ABK73079.1 - 2.5e-28 98.4 1.7 3.7e-28 97.8 1.7 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2064) Thioesterase PF00975.20 ABK73080.1 - 2.2e-42 145.7 0.0 2.8e-42 145.4 0.0 1.0 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 ABK73080.1 - 2.1e-08 35.0 9.7 3e-08 34.5 9.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ABK73080.1 - 0.0038 16.9 0.2 0.81 9.3 0.1 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ABK73080.1 - 0.011 15.1 0.1 0.021 14.1 0.1 1.6 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 ABK73080.1 - 0.058 13.2 0.0 0.18 11.5 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family PCNA_N PF00705.18 ABK73080.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, N-terminal domain DUF5336 PF17270.2 ABK73081.1 - 1.4e-44 151.8 16.8 1.4e-44 151.8 16.8 4.4 1 1 1 2 2 2 1 Family of unknown function (DUF5336) CPP1-like PF11833.8 ABK73081.1 - 0.068 12.8 2.7 0.13 11.9 2.7 1.5 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like P-II PF00543.22 ABK73082.1 - 1.1e-41 141.5 3.8 1.3e-41 141.3 3.8 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II DUF3240 PF11582.8 ABK73082.1 - 0.023 14.8 0.3 0.039 14.1 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3240) Peripla_BP_2 PF01497.18 ABK73083.1 - 4.9e-33 114.7 0.0 7.3e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein FAD_binding_3 PF01494.19 ABK73083.1 - 0.0064 15.8 0.5 0.056 12.7 0.5 2.0 1 1 0 1 1 1 1 FAD binding domain AMP-binding PF00501.28 ABK73084.1 - 3.9e-98 328.8 0.0 5e-98 328.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Peripla_BP_4 PF13407.6 ABK73086.1 - 3.1e-52 177.7 16.1 3.6e-52 177.5 16.1 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 ABK73086.1 - 6.7e-22 78.2 1.3 8.2e-22 77.9 1.3 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family ZnuA PF01297.17 ABK73086.1 - 0.084 12.3 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic BPD_transp_1 PF00528.22 ABK73087.1 - 1.5e-21 76.9 9.9 1.5e-21 76.9 9.9 2.1 2 1 1 3 3 3 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 ABK73087.1 - 1.1e-12 47.7 0.3 1.1e-12 47.7 0.3 3.6 4 0 0 4 4 4 1 N-terminal TM domain of oligopeptide transport permease C TraE PF05309.11 ABK73087.1 - 0.41 10.0 1.4 1.6 8.1 0.2 2.2 2 0 0 2 2 2 0 TraE protein DUF2070 PF09843.9 ABK73087.1 - 2.7 6.2 9.8 4.9 5.3 9.8 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) FA_desaturase PF00487.24 ABK73087.1 - 6.4 6.5 6.3 3.2 7.5 2.3 2.1 2 0 0 2 2 2 0 Fatty acid desaturase PBP PF01161.20 ABK73088.1 - 1.6e-18 67.3 0.0 2e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein FCD PF07729.12 ABK73089.1 - 1.3e-22 80.6 6.5 1.3e-22 80.6 6.5 1.9 3 0 0 3 3 3 1 FCD domain GntR PF00392.21 ABK73089.1 - 3.7e-20 71.3 2.0 7.7e-20 70.3 0.5 2.3 3 0 0 3 3 2 1 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 ABK73089.1 - 3e-06 27.1 0.1 1.2e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 ABK73089.1 - 1.8e-05 24.5 0.1 5.6e-05 22.9 0.1 1.9 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 ABK73089.1 - 2.8e-05 23.6 0.0 5.9e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding SgrR_N PF12793.7 ABK73089.1 - 0.00016 21.9 0.4 0.0035 17.6 0.0 2.3 2 0 0 2 2 2 1 Sugar transport-related sRNA regulator N-term HTH_11 PF08279.12 ABK73089.1 - 0.0002 21.3 0.0 0.00038 20.3 0.0 1.5 1 0 0 1 1 1 1 HTH domain TrmB PF01978.19 ABK73089.1 - 0.00079 19.3 0.0 0.0046 16.8 0.0 2.2 2 1 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_29 PF13551.6 ABK73089.1 - 0.0021 18.1 0.0 0.023 14.7 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn helix Fe_dep_repress PF01325.19 ABK73089.1 - 0.0021 18.2 0.0 0.0048 17.1 0.0 1.6 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain PaaX PF07848.12 ABK73089.1 - 0.0024 18.0 0.0 0.0061 16.7 0.0 1.7 1 0 0 1 1 1 1 PaaX-like protein HTH_AsnC-type PF13404.6 ABK73089.1 - 0.0074 16.1 0.3 0.021 14.7 0.3 1.8 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_DeoR PF08220.12 ABK73089.1 - 0.016 15.0 0.1 0.038 13.7 0.1 1.6 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain MarR PF01047.22 ABK73089.1 - 0.053 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 MarR family DUF1834 PF08873.11 ABK73089.1 - 0.06 13.1 0.2 0.34 10.6 0.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF1834) HTH_36 PF13730.6 ABK73089.1 - 0.085 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain TFIIE_alpha PF02002.17 ABK73089.1 - 0.092 12.6 0.0 0.26 11.1 0.0 1.9 2 0 0 2 2 2 0 TFIIE alpha subunit HemN_C PF06969.16 ABK73089.1 - 0.095 12.8 0.2 0.46 10.6 0.1 2.2 2 1 0 2 2 2 0 HemN C-terminal domain Rrf2 PF02082.20 ABK73089.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator KduI PF04962.12 ABK73092.1 - 2.3e-89 299.2 0.0 2.6e-89 299.0 0.0 1.0 1 0 0 1 1 1 1 KduI/IolB family AraC_binding_2 PF14525.6 ABK73092.1 - 0.049 13.3 0.1 0.099 12.3 0.1 1.5 1 0 0 1 1 1 0 AraC-binding-like domain MFS_1 PF07690.16 ABK73093.1 - 3.2e-41 141.4 41.7 3.2e-41 141.4 41.7 2.2 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK73093.1 - 1.2e-07 31.0 25.6 1.8e-07 30.4 11.1 3.1 3 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 ABK73093.1 - 0.35 9.2 20.6 0.014 13.8 13.8 2.0 1 1 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) HTH_Tnp_1 PF01527.20 ABK73094.1 - 4.6e-09 36.5 0.1 6.2e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 ABK73094.1 - 6.8e-06 25.7 0.6 1.7e-05 24.5 0.0 1.8 2 1 0 2 2 2 1 Homeodomain-like domain HTH_10 PF04967.12 ABK73094.1 - 0.0022 17.8 0.0 0.0088 15.8 0.0 2.0 2 1 1 3 3 3 1 HTH DNA binding domain HTH_28 PF13518.6 ABK73094.1 - 0.0031 17.6 0.0 0.0053 16.9 0.0 1.5 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_1_2 PF13022.6 ABK73094.1 - 0.0092 16.1 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix of insertion element transposase Sigma70_r4_2 PF08281.12 ABK73094.1 - 0.011 15.4 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_29 PF13551.6 ABK73094.1 - 0.016 15.2 0.0 0.028 14.5 0.0 1.4 1 1 0 1 1 1 0 Winged helix-turn helix ANT PF03374.14 ABK73094.1 - 0.04 14.2 0.0 0.062 13.6 0.0 1.3 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain Rrf2 PF02082.20 ABK73094.1 - 0.049 14.0 0.0 0.37 11.2 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator Terminase_5 PF06056.12 ABK73094.1 - 0.066 13.1 0.3 0.12 12.3 0.0 1.6 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) HTH_11 PF08279.12 ABK73094.1 - 0.072 13.0 0.1 0.36 10.8 0.0 2.0 2 0 0 2 2 2 0 HTH domain HTH_Tnp_ISL3 PF13542.6 ABK73094.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_AraC PF00165.23 ABK73094.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_7 PF02796.15 ABK73094.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase DUF977 PF06163.11 ABK73094.1 - 0.13 12.2 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) HTH_Tnp_4 PF13613.6 ABK73094.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease ECH_1 PF00378.20 ABK73095.1 - 1.8e-80 269.9 0.0 2e-80 269.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK73095.1 - 1e-33 117.2 0.3 2.3e-33 116.1 0.3 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 ABK73095.1 - 0.0072 16.3 0.1 1.1 9.1 0.0 2.2 2 0 0 2 2 2 2 Peptidase family S49 Glycos_transf_2 PF00535.26 ABK73096.1 - 4.2e-24 85.3 0.3 2.3e-23 82.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ABK73096.1 - 4.3e-23 82.4 1.8 7.9e-23 81.5 1.8 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ABK73096.1 - 3e-06 27.3 0.1 3.1e-05 24.0 0.1 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_4 PF13704.6 ABK73096.1 - 0.0096 16.4 0.0 0.058 13.9 0.0 2.0 1 1 1 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ABK73096.1 - 0.084 12.3 0.1 0.23 10.9 0.1 1.9 1 1 0 1 1 1 0 Glycosyl transferase family 21 DUF4946 PF16304.5 ABK73096.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4946) PsaM PF07465.13 ABK73096.1 - 0.16 11.7 1.6 0.26 11.1 0.2 2.1 2 0 0 2 2 2 0 Photosystem I protein M (PsaM) Pyr_redox_3 PF13738.6 ABK73097.1 - 2.8e-13 49.8 0.0 1.5e-12 47.4 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ABK73097.1 - 1.2e-12 47.0 0.0 1.8e-10 39.9 0.0 3.1 3 1 1 4 4 4 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ABK73097.1 - 4.5e-10 39.6 0.0 1.3e-09 38.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ABK73097.1 - 2.5e-09 36.8 0.0 1.2e-05 24.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ABK73097.1 - 3.7e-09 36.2 0.0 8e-06 25.2 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 ABK73097.1 - 1.1e-06 28.5 1.2 0.0019 17.8 0.0 2.8 2 2 2 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ABK73097.1 - 1.6e-06 28.2 1.0 0.59 10.1 0.0 3.7 3 1 1 4 4 4 3 FAD-NAD(P)-binding Amino_oxidase PF01593.24 ABK73097.1 - 5.5e-06 25.9 0.0 0.01 15.2 0.0 2.4 2 1 1 3 3 3 2 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 ABK73097.1 - 0.0059 15.9 0.3 0.0099 15.2 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 ABK73097.1 - 0.011 16.3 0.0 3.8 8.1 0.1 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 ABK73097.1 - 0.07 13.7 0.2 35 5.1 0.0 3.3 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Aldedh PF00171.22 ABK73098.1 - 1.1e-157 525.3 0.1 1.4e-157 525.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3102 PF11300.8 ABK73098.1 - 0.084 13.1 0.0 0.25 11.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3102) adh_short PF00106.25 ABK73099.1 - 5.6e-17 61.8 0.0 3.4e-16 59.3 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK73099.1 - 1.8e-13 50.6 0.0 9.6e-13 48.2 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK73099.1 - 0.17 11.8 0.4 0.25 11.2 0.4 1.2 1 0 0 1 1 1 0 KR domain adh_short_C2 PF13561.6 ABK73100.1 - 1.1e-57 195.3 0.5 1.4e-57 195.0 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK73100.1 - 7.7e-46 156.0 0.0 9.2e-46 155.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK73100.1 - 3.6e-05 23.7 0.4 0.00011 22.2 0.4 1.8 1 1 0 1 1 1 1 KR domain SnoaL PF07366.12 ABK73101.1 - 6e-34 116.6 0.0 6.7e-34 116.4 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 ABK73101.1 - 1.6e-13 51.1 0.8 2.2e-13 50.7 0.2 1.5 2 0 0 2 2 2 1 SnoaL-like domain DUF4440 PF14534.6 ABK73101.1 - 0.051 14.0 0.1 0.12 12.8 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4440) ABC_membrane PF00664.23 ABK73102.1 - 7.8e-59 199.6 5.2 1e-58 199.2 5.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 ABK73102.1 - 3.2e-31 108.7 0.0 6e-31 107.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 ABK73102.1 - 0.00022 21.5 0.1 0.008 16.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC_membrane_2 PF06472.15 ABK73102.1 - 0.00041 19.8 1.3 0.0008 18.9 1.3 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 SMC_N PF02463.19 ABK73102.1 - 0.00054 19.5 0.2 0.056 12.9 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ABK73102.1 - 0.00086 19.7 0.1 0.0031 17.9 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 ABK73102.1 - 0.0012 18.6 0.1 0.0039 16.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ABK73102.1 - 0.0015 18.5 0.0 0.0031 17.4 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_28 PF13521.6 ABK73102.1 - 0.0032 17.7 1.1 0.45 10.7 0.1 2.5 1 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 ABK73102.1 - 0.0094 16.5 0.0 0.016 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 ABK73102.1 - 0.011 15.5 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ABK73102.1 - 0.011 15.9 0.0 0.03 14.4 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.29 ABK73102.1 - 0.016 15.6 0.0 0.074 13.5 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 ABK73102.1 - 0.035 13.2 0.0 0.072 12.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.6 ABK73102.1 - 0.044 13.4 0.3 0.85 9.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 ABK73102.1 - 0.054 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF87 PF01935.17 ABK73102.1 - 0.065 13.3 0.1 0.16 12.0 0.1 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 ABK73102.1 - 0.066 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 ABK73102.1 - 0.078 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 ABK73102.1 - 0.079 12.8 0.2 1.7 8.4 0.1 2.2 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 ABK73102.1 - 0.086 13.1 0.0 1.3 9.4 0.0 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 ABK73102.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 ABK73102.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain IstB_IS21 PF01695.17 ABK73102.1 - 0.11 12.2 1.1 6.1 6.5 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_18 PF13238.6 ABK73102.1 - 0.16 12.6 0.0 0.27 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 ABK73102.1 - 0.2 11.9 0.0 0.39 10.9 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DEAD PF00270.29 ABK73102.1 - 0.2 11.4 0.4 2.1 8.1 0.4 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase TetR_C_1 PF02909.17 ABK73103.1 - 2.1e-07 30.9 0.1 3e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK73103.1 - 0.00014 21.6 0.0 0.00037 20.2 0.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_32 PF13565.6 ABK73103.1 - 0.079 13.6 0.8 0.14 12.7 0.8 1.4 1 0 0 1 1 1 0 Homeodomain-like domain pPIWI_RE_Z PF18155.1 ABK73103.1 - 0.28 11.1 2.5 4.1 7.3 0.5 2.5 2 1 1 3 3 3 0 pPIWI RE three-gene island domain Z HTH_17 PF12728.7 ABK73103.1 - 0.28 11.4 1.0 13 6.0 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain DEDD_Tnp_IS110 PF01548.17 ABK73104.1 - 1.6e-37 128.7 0.7 3.6e-37 127.6 0.2 1.8 2 0 0 2 2 2 1 Transposase Transposase_20 PF02371.16 ABK73104.1 - 1.3e-10 41.5 0.1 4.3e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 Transposase IS116/IS110/IS902 family DUF2786 PF10979.8 ABK73105.1 - 1.5e-13 50.4 2.5 1.5e-13 50.4 2.5 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2786) T2SSF PF00482.23 ABK73105.1 - 0.077 13.0 3.8 0.21 11.5 0.3 2.7 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein F ILVD_EDD PF00920.21 ABK73106.1 - 1.9e-160 534.9 0.1 2.1e-160 534.7 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family Polyketide_cyc2 PF10604.9 ABK73108.1 - 0.038 14.3 0.1 0.058 13.7 0.1 1.4 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport SBP_bac_8 PF13416.6 ABK73110.1 - 3.2e-29 102.6 8.7 4.7e-29 102.1 8.7 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 ABK73110.1 - 7.4e-22 78.0 1.7 1e-21 77.5 1.7 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 ABK73110.1 - 9.2e-11 42.2 10.1 1.3e-10 41.8 10.1 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 ABK73110.1 - 1.5e-05 24.9 0.1 8e-05 22.5 0.1 2.1 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein Phosphonate-bd PF12974.7 ABK73110.1 - 0.012 15.2 0.1 0.027 14.1 0.0 1.5 2 0 0 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Aldedh PF00171.22 ABK73112.1 - 1.1e-149 498.9 6.7 1.2e-149 498.8 6.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family CbiG_C PF01890.16 ABK73112.1 - 0.12 13.0 2.4 0.27 11.8 2.4 1.6 1 0 0 1 1 1 0 Cobalamin synthesis G C-terminus DUF2292 PF10055.9 ABK73112.1 - 0.13 11.9 0.1 1.2 8.8 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized small protein (DUF2292) LuxC PF05893.14 ABK73112.1 - 0.15 11.1 0.0 0.35 9.9 0.0 1.6 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF1949 PF09186.11 ABK73112.1 - 0.49 10.3 1.7 2.3 8.2 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1949) Lactamase_B PF00753.27 ABK73114.1 - 9.7e-17 61.6 6.2 1.3e-16 61.2 6.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ABK73114.1 - 6.8e-05 22.5 0.2 8.6e-05 22.1 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Dyp_perox PF04261.12 ABK73115.1 - 2.9e-98 328.9 0.0 4.3e-98 328.3 0.0 1.2 1 0 0 1 1 1 1 Dyp-type peroxidase family DEDD_Tnp_IS110 PF01548.17 ABK73116.1 - 1.6e-37 128.7 0.7 3.6e-37 127.6 0.2 1.8 2 0 0 2 2 2 1 Transposase Transposase_20 PF02371.16 ABK73116.1 - 2.4e-10 40.6 0.1 8e-10 38.9 0.0 2.0 2 0 0 2 2 2 1 Transposase IS116/IS110/IS902 family Acyl-CoA_dh_1 PF00441.24 ABK73117.1 - 1.3e-31 109.8 0.2 1.9e-31 109.3 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK73117.1 - 1.4e-28 99.8 0.4 6.1e-28 97.7 0.3 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ABK73117.1 - 4.2e-25 87.8 0.0 1.2e-24 86.3 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ABK73117.1 - 6.3e-11 42.7 0.0 1e-10 42.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 ABK73117.1 - 0.0094 16.5 0.0 0.019 15.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl_transf_3 PF01757.22 ABK73118.1 - 2.9e-18 66.0 37.9 2.9e-18 66.0 37.9 1.6 2 0 0 2 2 2 1 Acyltransferase family Oxidored_q2 PF00420.24 ABK73118.1 - 0.021 14.4 4.5 0.032 13.9 1.0 2.9 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L CcmH PF03918.14 ABK73118.1 - 0.41 9.9 7.7 0.75 9.1 0.4 3.7 3 0 0 3 3 3 0 Cytochrome C biogenesis protein DHBP_synthase PF00926.19 ABK73119.1 - 1.1e-84 282.8 0.1 2.5e-84 281.6 0.1 1.6 2 0 0 2 2 2 1 3,4-dihydroxy-2-butanone 4-phosphate synthase GTP_cyclohydro2 PF00925.20 ABK73119.1 - 4.2e-73 244.3 0.0 1e-72 243.1 0.0 1.6 2 0 0 2 2 2 1 GTP cyclohydrolase II Molybdopterin PF00384.22 ABK73120.1 - 3.9e-74 250.2 0.0 4.9e-74 249.8 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 ABK73120.1 - 6.2e-26 90.6 1.3 9.6e-26 90.0 0.3 1.9 2 0 0 2 2 1 1 Molydopterin dinucleotide binding domain Fer2_4 PF13510.6 ABK73120.1 - 4.4e-25 87.5 0.9 1.3e-24 86.0 0.9 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 ABK73120.1 - 7.3e-16 57.4 0.2 7.3e-16 57.4 0.2 2.4 3 0 0 3 3 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer4_7 PF12838.7 ABK73120.1 - 9.7e-14 51.7 0.0 5.9e-05 23.6 11.9 4.1 1 1 3 4 4 4 3 4Fe-4S dicluster domain Molybdop_Fe4S4 PF04879.16 ABK73120.1 - 1.1e-13 50.9 1.1 3.2e-13 49.4 1.1 1.9 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain Fer4_9 PF13187.6 ABK73120.1 - 1.9e-07 31.2 5.6 1.9e-07 31.2 5.6 3.5 3 1 1 4 4 3 1 4Fe-4S dicluster domain Fer4 PF00037.27 ABK73120.1 - 5.6e-07 29.1 10.1 2.1e-05 24.1 1.2 3.5 4 0 0 4 4 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 ABK73120.1 - 1.3e-05 25.3 7.7 1.3e-05 25.3 7.7 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 ABK73120.1 - 4.1e-05 23.5 11.0 8.7e-05 22.4 1.6 4.0 5 0 0 5 5 3 2 4Fe-4S binding domain Fer4_2 PF12797.7 ABK73120.1 - 0.0002 21.2 12.5 0.00054 19.9 2.4 4.1 5 0 0 5 5 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 ABK73120.1 - 0.0023 18.0 14.5 0.0023 18.0 14.5 3.4 3 1 1 4 4 4 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 ABK73120.1 - 0.015 16.2 4.1 0.015 16.2 4.1 3.5 3 1 0 3 3 2 0 4Fe-4S double cluster binding domain Fer4_18 PF13746.6 ABK73120.1 - 0.044 14.0 12.3 0.45 10.7 2.1 3.2 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 ABK73120.1 - 0.066 14.0 6.6 4.8 8.0 1.1 3.0 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_13 PF13370.6 ABK73120.1 - 0.16 12.5 14.6 2 9.0 4.7 3.0 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_17 PF13534.6 ABK73120.1 - 0.36 11.4 16.8 0.36 11.4 1.0 3.8 4 0 0 4 4 3 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 ABK73120.1 - 1.1 10.1 13.2 5.7 7.9 0.4 3.1 3 0 0 3 3 2 0 4Fe-4S dicluster domain ABC_tran PF00005.27 ABK73121.1 - 6.4e-64 214.6 0.0 1.4e-35 122.8 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ABK73121.1 - 5.9e-12 46.0 12.6 3.9e-05 23.6 0.1 4.1 2 2 2 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK73121.1 - 4.6e-11 42.6 0.1 1e-05 25.1 0.0 3.1 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ABK73121.1 - 1.4e-09 38.3 3.1 0.00082 19.7 0.2 3.2 2 2 0 2 2 2 2 AAA domain oligo_HPY PF08352.12 ABK73121.1 - 1.1e-08 35.5 0.0 0.0004 20.8 0.0 2.6 2 0 0 2 2 2 2 Oligopeptide/dipeptide transporter, C-terminal region RsgA_GTPase PF03193.16 ABK73121.1 - 4.3e-08 33.3 0.1 0.0097 15.8 0.1 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 ABK73121.1 - 7.8e-08 31.9 1.4 0.0065 16.2 0.2 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 ABK73121.1 - 6.1e-07 30.0 8.1 0.0032 17.9 0.6 3.0 2 2 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 ABK73121.1 - 1.8e-06 28.2 0.3 0.023 14.9 0.1 2.7 2 1 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 ABK73121.1 - 3.7e-06 27.1 0.2 0.085 13.1 0.1 4.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 ABK73121.1 - 1.2e-05 25.0 1.4 0.46 10.0 0.1 3.9 4 0 0 4 4 3 2 AAA domain AAA_24 PF13479.6 ABK73121.1 - 3.4e-05 23.7 0.9 0.12 12.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 ABK73121.1 - 0.00011 22.2 0.7 0.66 10.0 0.1 3.0 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) NACHT PF05729.12 ABK73121.1 - 0.00015 21.7 1.2 0.22 11.4 0.0 2.4 2 0 0 2 2 2 2 NACHT domain MMR_HSR1 PF01926.23 ABK73121.1 - 0.00017 21.7 0.2 0.089 12.9 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Mg_chelatase PF01078.21 ABK73121.1 - 0.00042 19.8 0.3 0.53 9.6 0.2 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI G-alpha PF00503.20 ABK73121.1 - 0.00042 19.6 0.0 0.023 13.9 0.0 2.1 2 0 0 2 2 2 1 G-protein alpha subunit AAA_7 PF12775.7 ABK73121.1 - 0.00044 19.8 0.6 0.51 9.8 0.1 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region Zeta_toxin PF06414.12 ABK73121.1 - 0.0007 18.9 0.1 0.094 12.0 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA PF00004.29 ABK73121.1 - 0.00075 19.9 0.9 3.4 8.1 0.0 3.6 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 ABK73121.1 - 0.00087 18.4 1.1 0.54 9.3 0.3 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_23 PF13476.6 ABK73121.1 - 0.00093 19.8 0.6 0.28 11.6 0.2 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 ABK73121.1 - 0.0012 19.2 0.5 0.3 11.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 ABK73121.1 - 0.0015 18.7 4.4 0.18 11.9 0.5 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain MobB PF03205.14 ABK73121.1 - 0.0016 18.3 1.1 0.19 11.6 0.1 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.18 ABK73121.1 - 0.0025 17.2 0.4 0.72 9.1 0.2 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family PRK PF00485.18 ABK73121.1 - 0.0026 17.5 0.0 2 8.1 0.0 2.3 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AIG1 PF04548.16 ABK73121.1 - 0.0029 17.0 1.0 0.25 10.7 0.0 2.6 2 0 0 2 2 2 1 AIG1 family ATP-synt_ab PF00006.25 ABK73121.1 - 0.004 16.8 0.1 0.45 10.1 0.0 2.4 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.6 ABK73121.1 - 0.0041 16.9 2.4 0.96 9.1 0.3 2.7 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 ABK73121.1 - 0.0046 17.0 0.5 1.5 8.8 0.0 2.5 2 1 0 2 2 2 1 Dynamin family TsaE PF02367.17 ABK73121.1 - 0.0051 16.8 0.6 1.6 8.7 0.2 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 ABK73121.1 - 0.006 16.2 0.7 0.3 10.7 0.2 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Sigma54_activat PF00158.26 ABK73121.1 - 0.0062 16.3 0.2 1.1 8.9 0.0 2.8 3 0 0 3 3 2 1 Sigma-54 interaction domain RNA_helicase PF00910.22 ABK73121.1 - 0.008 16.6 0.1 5.1 7.5 0.1 2.4 2 0 0 2 2 2 0 RNA helicase Septin PF00735.18 ABK73121.1 - 0.0092 15.3 1.0 0.25 10.6 0.1 2.1 2 0 0 2 2 2 1 Septin Roc PF08477.13 ABK73121.1 - 0.011 16.0 0.2 2 8.6 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 ABK73121.1 - 0.011 15.2 1.1 25 4.2 0.0 3.9 4 0 0 4 4 4 0 Bacterial TniB protein NB-ARC PF00931.22 ABK73121.1 - 0.016 14.4 2.7 1.2 8.2 0.1 2.5 3 0 0 3 3 2 0 NB-ARC domain IstB_IS21 PF01695.17 ABK73121.1 - 0.018 14.8 0.2 0.9 9.2 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein SRP54 PF00448.22 ABK73121.1 - 0.028 14.1 0.0 3 7.4 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain APS_kinase PF01583.20 ABK73121.1 - 0.03 14.2 0.8 3.8 7.4 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF3987 PF13148.6 ABK73121.1 - 0.031 13.3 2.1 3.2 6.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) AAA_15 PF13175.6 ABK73121.1 - 0.04 13.6 0.0 3.8 7.1 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain Pox_A32 PF04665.12 ABK73121.1 - 0.053 13.0 1.2 2.1 7.7 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein NTPase_1 PF03266.15 ABK73121.1 - 0.067 13.1 4.1 1 9.2 0.3 3.0 3 0 0 3 3 3 0 NTPase ATPase PF06745.13 ABK73121.1 - 0.076 12.3 2.8 8.9 5.6 0.1 3.3 4 0 0 4 4 4 0 KaiC ATP_bind_1 PF03029.17 ABK73121.1 - 0.13 12.0 2.8 0.54 10.0 0.2 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Imm7 PF15585.6 ABK73121.1 - 0.14 12.4 0.0 23 5.3 0.0 2.6 2 0 0 2 2 2 0 Immunity protein 7 AAA_10 PF12846.7 ABK73121.1 - 0.15 11.0 0.3 2.3 7.1 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain AAA_18 PF13238.6 ABK73121.1 - 0.15 12.6 0.3 15 6.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 ABK73121.1 - 0.34 9.6 4.5 1.2 7.9 0.0 3.1 3 1 0 3 3 3 0 Predicted ATPase of the ABC class CbiA PF01656.23 ABK73121.1 - 1.1 9.3 3.2 15 5.6 0.4 2.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain NAD_binding_2 PF03446.15 ABK73122.1 - 5.1e-33 114.5 0.1 1e-32 113.5 0.0 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ABK73122.1 - 9.9e-14 51.6 0.7 1.5e-13 51.1 0.7 1.2 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 ABK73122.1 - 0.001 19.6 0.0 0.0057 17.2 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 ABK73122.1 - 0.015 14.9 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 ABK73122.1 - 0.036 13.4 0.0 0.069 12.5 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 ABK73122.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 ABK73123.1 - 8.7e-58 195.6 0.2 1.7e-57 194.6 0.2 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK73123.1 - 1.9e-53 180.8 0.5 1.2e-52 178.2 0.5 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK73123.1 - 6.9e-09 35.9 3.6 2e-08 34.3 0.1 2.1 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 ABK73123.1 - 4.1e-07 29.7 0.1 1.4e-06 27.9 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Amdase PF17645.1 ABK73123.1 - 0.0013 18.4 0.1 0.0017 18.0 0.1 1.1 1 0 0 1 1 1 1 Arylmalonate decarboxylase DUF1776 PF08643.10 ABK73123.1 - 0.0015 18.0 0.0 0.002 17.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) 3Beta_HSD PF01073.19 ABK73123.1 - 0.1 11.6 0.1 0.13 11.2 0.1 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ABK73123.1 - 0.16 11.1 0.1 0.21 10.6 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Cutinase PF01083.22 ABK73124.1 - 7.7e-45 153.0 0.0 9.1e-45 152.8 0.0 1.0 1 0 0 1 1 1 1 Cutinase Abhydrolase_6 PF12697.7 ABK73124.1 - 0.022 15.4 1.0 0.024 15.2 1.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 ABK73124.1 - 0.25 11.1 0.1 0.45 10.3 0.1 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Arginase PF00491.21 ABK73126.1 - 3e-86 289.4 1.3 3.5e-86 289.2 1.3 1.0 1 0 0 1 1 1 1 Arginase family BPD_transp_1 PF00528.22 ABK73127.1 - 1e-15 58.0 15.7 1e-15 58.0 15.7 1.9 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF5592 PF17332.2 ABK73127.1 - 0.029 14.9 2.4 0.2 12.2 0.7 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5592) BIV_Env PF05858.12 ABK73127.1 - 0.038 12.2 1.0 0.062 11.5 1.0 1.2 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) Fer2_2 PF01799.20 ABK73128.1 - 1.3e-26 92.4 0.0 2.2e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 ABK73128.1 - 1.3e-06 28.2 0.4 1.3e-06 28.2 0.4 2.3 1 1 1 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 ABK73128.1 - 8.8e-06 25.7 0.2 1.4e-05 25.1 0.2 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 ABK73128.1 - 0.13 12.4 2.3 0.26 11.4 2.3 1.7 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain adh_short_C2 PF13561.6 ABK73129.1 - 5.5e-52 176.7 1.8 8e-52 176.1 1.8 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK73129.1 - 2.9e-41 141.1 0.7 3.6e-41 140.8 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK73129.1 - 3.1e-09 37.0 0.9 4.3e-09 36.5 0.9 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 ABK73129.1 - 0.0076 16.5 0.4 0.15 12.3 0.2 2.2 1 1 1 2 2 2 2 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 ABK73129.1 - 0.047 13.8 0.1 0.15 12.1 0.1 1.8 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1776 PF08643.10 ABK73129.1 - 0.077 12.3 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) SfLAP PF11139.8 ABK73130.1 - 1.2e-62 211.2 28.4 1.3e-62 211.0 28.4 1.0 1 0 0 1 1 1 1 Sap, sulfolipid-1-addressing protein DUF4728 PF15860.5 ABK73130.1 - 0.76 10.5 4.0 0.41 11.4 0.6 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4728) EutQ PF06249.12 ABK73131.1 - 3.2e-12 46.5 0.0 3.8e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_2 PF07883.11 ABK73131.1 - 0.00062 19.4 0.0 0.00094 18.9 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 ABK73131.1 - 0.026 14.2 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Amidohydro_2 PF04909.14 ABK73132.1 - 1.5e-36 126.7 6.6 1.7e-36 126.5 6.6 1.1 1 0 0 1 1 1 1 Amidohydrolase DSHCT PF08148.12 ABK73134.1 - 8.7e-39 132.8 0.0 3e-38 131.1 0.0 1.9 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 ABK73134.1 - 1.2e-18 67.5 0.0 2.8e-18 66.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 ABK73134.1 - 4.4e-09 36.6 0.0 6.7e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ABK73134.1 - 1.3e-05 25.5 0.0 2.9e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.6 ABK73134.1 - 0.0013 18.8 0.0 0.019 14.9 0.0 2.1 2 0 0 2 2 2 1 rRNA-processing arch domain AAA_22 PF13401.6 ABK73134.1 - 0.017 15.4 0.1 0.1 12.9 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 ABK73134.1 - 0.045 13.5 1.0 0.12 12.1 0.0 2.3 2 1 0 2 2 2 0 AAA domain ThiC_Rad_SAM PF01964.18 ABK73135.1 - 8.6e-127 423.4 0.2 1.1e-126 423.1 0.2 1.0 1 0 0 1 1 1 1 Radical SAM ThiC family ThiC-associated PF13667.6 ABK73135.1 - 9.1e-07 28.6 0.1 4.9e-06 26.3 0.0 2.3 2 1 0 2 2 2 1 ThiC-associated domain Transglycosylas PF06737.14 ABK73137.1 - 2.8e-35 120.8 3.8 3.6e-35 120.5 3.8 1.1 1 0 0 1 1 1 1 Transglycosylase-like domain Esterase PF00756.20 ABK73138.1 - 1.3e-62 211.7 1.2 1.7e-62 211.4 1.2 1.1 1 0 0 1 1 1 1 Putative esterase ribosomal_L24 PF17136.4 ABK73139.1 - 3.1e-24 85.1 1.7 4.8e-24 84.5 1.7 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 ABK73139.1 - 3.1e-08 33.3 1.1 3.1e-08 33.3 1.1 2.5 3 0 0 3 3 3 1 KOW motif DUF4864 PF16156.5 ABK73139.1 - 0.11 13.2 0.0 0.15 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4864) DEDD_Tnp_IS110 PF01548.17 ABK73140.1 - 1.6e-37 128.7 0.7 3.6e-37 127.6 0.2 1.8 2 0 0 2 2 2 1 Transposase Transposase_20 PF02371.16 ABK73140.1 - 1.3e-10 41.5 0.1 4.3e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 Transposase IS116/IS110/IS902 family GalP_UDP_transf PF01087.22 ABK73141.1 - 9.9e-46 156.5 0.0 1.6e-45 155.8 0.0 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 ABK73141.1 - 3.2e-15 56.2 0.0 4.6e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain KNOX2 PF03791.13 ABK73141.1 - 0.0092 15.5 0.4 0.02 14.4 0.4 1.5 1 0 0 1 1 1 1 KNOX2 domain DUF4931 PF16285.5 ABK73141.1 - 0.021 14.1 0.0 0.095 12.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4931) Mce4_CUP1 PF11887.8 ABK73142.1 - 7.3e-12 45.3 0.3 1.3e-11 44.5 0.3 1.4 1 1 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative MlaD PF02470.20 ABK73142.1 - 2.4e-11 43.8 0.0 4.2e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 MlaD protein Baculo_PEP_C PF04513.12 ABK73142.1 - 0.00074 19.6 1.1 0.099 12.7 0.1 2.6 1 1 2 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2420 PF10336.9 ABK73142.1 - 0.093 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2420) DASH_Dad3 PF08656.10 ABK73142.1 - 0.21 11.7 0.2 0.6 10.2 0.0 1.7 2 0 0 2 2 2 0 DASH complex subunit Dad3 Beta-lactamase PF00144.24 ABK73144.1 - 7.2e-61 206.3 4.2 8.4e-61 206.0 4.2 1.0 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 ABK73144.1 - 8.1e-08 32.1 0.0 0.00026 20.7 0.0 2.2 2 0 0 2 2 2 2 Beta-lactamase enzyme family Cm_res_leader PF08077.11 ABK73144.1 - 0.1 12.7 2.3 0.71 10.2 0.1 3.3 2 0 0 2 2 2 0 Chloramphenicol resistance gene leader peptide Amidohydro_1 PF01979.20 ABK73145.1 - 1.2e-27 97.1 0.0 2e-27 96.4 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ABK73145.1 - 3.5e-15 56.4 3.4 3.1e-07 30.2 0.0 2.7 2 1 0 2 2 2 2 Amidohydrolase family LytR_C PF13399.6 ABK73146.1 - 3.2e-13 50.5 0.0 5.2e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 LytR cell envelope-related transcriptional attenuator SBP_bac_5 PF00496.22 ABK73147.1 - 3.2e-70 237.0 0.7 4e-70 236.7 0.7 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle ORF_12_N PF18042.1 ABK73147.1 - 0.12 12.8 0.0 42 4.6 0.0 3.2 3 0 0 3 3 3 0 ORF 12 gene product N-terminal GLF PF03275.13 ABK73148.1 - 3.4e-81 271.9 0.6 4.5e-81 271.4 0.6 1.2 1 0 0 1 1 1 1 UDP-galactopyranose mutase NAD_binding_8 PF13450.6 ABK73148.1 - 4.5e-19 68.4 0.0 1.3e-18 67.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 ABK73148.1 - 8.2e-06 25.4 0.0 1.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 ABK73148.1 - 3.5e-05 23.3 0.0 7.8e-05 22.2 0.0 1.6 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 ABK73148.1 - 0.0002 21.9 0.0 0.00064 20.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ABK73148.1 - 0.00044 19.9 0.1 0.0012 18.5 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ABK73148.1 - 0.002 17.4 0.0 0.0035 16.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ABK73148.1 - 0.0042 17.1 0.0 0.0097 15.9 0.0 1.6 1 1 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.17 ABK73148.1 - 0.015 14.6 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 ABK73148.1 - 0.038 13.1 0.0 0.055 12.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Fe-ADH PF00465.19 ABK73149.1 - 2e-116 388.8 5.3 2.2e-116 388.6 5.3 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 ABK73149.1 - 8.4e-20 71.5 3.9 5.3e-18 65.6 3.9 2.1 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase LysR_substrate PF03466.20 ABK73150.1 - 9.4e-30 103.5 3.9 9.4e-30 103.5 3.9 1.8 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 ABK73150.1 - 8.8e-19 67.2 5.5 2e-18 66.1 5.5 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_IclR PF09339.10 ABK73150.1 - 0.038 13.8 1.1 0.46 10.3 0.5 2.7 2 0 0 2 2 2 0 IclR helix-turn-helix domain Fe_dep_repress PF01325.19 ABK73150.1 - 0.091 13.0 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain adh_short_C2 PF13561.6 ABK73151.1 - 2.9e-42 144.8 4.4 6.8e-42 143.6 4.4 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK73151.1 - 1.6e-36 125.7 3.4 5e-36 124.0 3.4 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 ABK73151.1 - 0.0017 17.9 1.6 0.0036 16.8 1.6 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 ABK73151.1 - 0.0023 17.9 2.9 0.065 13.1 2.5 2.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ABK73151.1 - 0.0056 16.6 2.5 0.0083 16.0 2.5 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DUF4684 PF15736.5 ABK73151.1 - 1.1 7.8 11.0 0.34 9.5 4.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4684) CT_C_D PF02682.16 ABK73152.1 - 2.8e-64 216.6 0.3 3.2e-64 216.4 0.3 1.0 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D CoA_trans PF01144.23 ABK73153.1 - 0.089 12.2 0.0 0.25 10.7 0.0 1.9 1 1 0 1 1 1 0 Coenzyme A transferase FCD PF07729.12 ABK73154.1 - 1e-18 67.9 7.9 1e-18 67.9 7.9 1.9 2 0 0 2 2 2 1 FCD domain GntR PF00392.21 ABK73154.1 - 4.2e-18 64.8 0.8 9.8e-18 63.6 0.8 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Rrf2 PF02082.20 ABK73154.1 - 3.4e-07 30.5 0.0 6.1e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator HTH_11 PF08279.12 ABK73154.1 - 2.6e-06 27.3 0.4 2.2e-05 24.3 0.1 2.2 2 0 0 2 2 2 1 HTH domain HTH_41 PF14502.6 ABK73154.1 - 4.4e-06 26.3 0.0 7.8e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 ABK73154.1 - 2e-05 24.5 0.1 3.9e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_24 PF13412.6 ABK73154.1 - 7.9e-05 22.1 0.4 0.00019 20.9 0.1 1.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 ABK73154.1 - 0.00039 20.2 0.0 0.00067 19.5 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 ABK73154.1 - 0.00076 19.3 2.7 0.0012 18.7 0.6 2.4 3 0 0 3 3 2 1 MarR family HTH_29 PF13551.6 ABK73154.1 - 0.0014 18.6 0.1 0.0045 17.0 0.1 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_20 PF12840.7 ABK73154.1 - 0.0021 18.1 0.6 0.0021 18.1 0.6 2.4 3 0 0 3 3 2 1 Helix-turn-helix domain Fe_dep_repress PF01325.19 ABK73154.1 - 0.0033 17.6 0.0 0.017 15.3 0.0 1.9 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain HTH_DeoR PF08220.12 ABK73154.1 - 0.0046 16.7 0.2 0.012 15.3 0.2 1.6 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_IclR PF09339.10 ABK73154.1 - 0.0084 15.9 3.3 0.037 13.8 0.3 2.9 3 0 0 3 3 3 1 IclR helix-turn-helix domain HTH_17 PF12728.7 ABK73154.1 - 0.0087 16.2 0.1 0.022 15.0 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 ABK73154.1 - 0.013 15.6 0.2 0.36 11.0 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain MerR PF00376.23 ABK73154.1 - 0.017 14.8 1.1 0.11 12.3 1.1 2.1 1 1 0 1 1 1 0 MerR family regulatory protein MarR PF01047.22 ABK73154.1 - 0.022 14.7 0.1 0.048 13.6 0.1 1.5 1 0 0 1 1 1 0 MarR family HTH_23 PF13384.6 ABK73154.1 - 0.022 14.5 2.2 0.21 11.4 0.1 2.7 2 0 0 2 2 2 0 Homeodomain-like domain Peptidase_M75 PF09375.10 ABK73154.1 - 0.024 14.1 1.6 1.1 8.7 1.3 2.1 2 0 0 2 2 2 0 Imelysin PaaX PF07848.12 ABK73154.1 - 0.052 13.8 0.3 0.15 12.3 0.3 1.7 1 0 0 1 1 1 0 PaaX-like protein TFIIE_alpha PF02002.17 ABK73154.1 - 0.078 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 TFIIE alpha subunit HTH_27 PF13463.6 ABK73154.1 - 0.1 13.1 0.3 0.27 11.7 0.0 1.9 2 0 0 2 2 1 0 Winged helix DNA-binding domain FCD PF07729.12 ABK73155.1 - 5.5e-21 75.3 4.6 6.6e-21 75.0 3.5 1.7 2 0 0 2 2 2 1 FCD domain GntR PF00392.21 ABK73155.1 - 9.6e-21 73.2 0.2 8.1e-20 70.3 0.1 2.3 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 ABK73155.1 - 0.00056 19.9 0.1 0.0021 18.1 0.1 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 ABK73155.1 - 0.0071 16.3 0.1 0.036 14.0 0.0 2.1 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_CodY PF08222.11 ABK73155.1 - 0.011 15.3 0.0 0.027 14.0 0.0 1.7 1 0 0 1 1 1 0 CodY helix-turn-helix domain Rrf2 PF02082.20 ABK73155.1 - 0.057 13.8 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator TrmB PF01978.19 ABK73155.1 - 0.069 13.0 0.0 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_17 PF12728.7 ABK73155.1 - 0.082 13.1 0.0 0.21 11.8 0.0 1.8 1 1 0 1 1 1 0 Helix-turn-helix domain Glyoxalase_4 PF13669.6 ABK73156.1 - 6.5e-22 77.9 0.0 1.7e-21 76.5 0.0 1.6 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 ABK73156.1 - 1.3e-12 48.1 0.0 1.5e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 ABK73156.1 - 6e-11 42.8 0.3 1.4e-10 41.6 0.3 1.7 1 1 0 1 1 1 1 Glyoxalase-like domain DUF1338 PF07063.13 ABK73156.1 - 0.15 11.2 0.0 0.81 8.8 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1338) DUF222 PF02720.17 ABK73158.1 - 1.3e-43 149.6 11.4 4.7e-37 128.1 9.8 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF222) Neisseria_TspB PF05616.13 ABK73158.1 - 0.1 11.1 16.6 0.17 10.3 16.6 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein HTH_Tnp_1 PF01527.20 ABK73160.1 - 4.3e-07 30.1 3.8 2e-06 28.0 3.8 2.0 1 1 0 1 1 1 1 Transposase HTH_23 PF13384.6 ABK73160.1 - 0.0028 17.4 0.4 0.0089 15.8 0.4 1.9 1 1 0 1 1 1 1 Homeodomain-like domain HMMR_N PF15905.5 ABK73160.1 - 0.015 14.8 0.2 0.024 14.1 0.1 1.4 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal HTH_28 PF13518.6 ABK73160.1 - 0.026 14.6 0.4 0.053 13.7 0.4 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_terminase PF10668.9 ABK73160.1 - 0.062 13.3 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Phage terminase small subunit Pentapeptide_4 PF13599.6 ABK73161.1 - 5e-35 119.5 8.1 5.5e-12 45.7 0.0 3.0 1 1 3 4 4 4 4 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 ABK73161.1 - 8e-28 95.7 12.0 4.1e-10 39.1 0.0 4.4 1 1 4 5 5 5 5 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 ABK73161.1 - 2.1e-19 69.4 24.1 5.5e-07 29.6 4.5 3.9 1 1 4 5 5 5 5 Pentapeptide repeats (9 copies) AMP-binding PF00501.28 ABK73162.1 - 5.6e-76 255.8 0.0 6.8e-76 255.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK73162.1 - 6.4e-25 87.9 0.1 1.5e-24 86.7 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain STAS PF01740.21 ABK73163.1 - 2e-11 43.6 0.0 2.2e-11 43.4 0.0 1.0 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 ABK73163.1 - 1.6e-10 41.2 2.5 2.4e-10 40.6 2.5 1.3 1 0 0 1 1 1 1 STAS domain Glucosamine_iso PF01182.20 ABK73164.1 - 8.9e-76 254.7 0.0 1e-75 254.5 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Glyco_transf_28 PF03033.20 ABK73165.1 - 2.5e-06 27.6 0.0 5.1e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 ABK73165.1 - 0.069 11.9 0.0 0.37 9.5 0.0 1.9 2 0 0 2 2 2 0 UDP-glucoronosyl and UDP-glucosyl transferase Peptidase_M48 PF01435.18 ABK73166.1 - 2.4e-39 135.1 0.0 3.9e-39 134.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 ABK73166.1 - 0.011 15.0 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 Oxidored_molyb PF00174.19 ABK73167.1 - 4.2e-28 98.1 0.0 5.2e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Bac_luciferase PF00296.20 ABK73168.1 - 2e-46 158.9 5.3 2.6e-46 158.5 5.3 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase CysA_C_terminal PF17850.1 ABK73168.1 - 0.063 13.9 0.1 0.23 12.0 0.1 2.1 1 0 0 1 1 1 0 CysA C-terminal regulatory domain Ribosomal_S4 PF00163.19 ABK73169.1 - 0.16 12.9 0.0 0.37 11.7 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S4/S9 N-terminal domain Big_2 PF02368.18 ABK73170.1 - 0.0029 17.5 1.4 0.0029 17.5 1.4 1.7 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 2) MDMPI_N PF11716.8 ABK73171.1 - 1.9e-08 35.1 9.7 4.7e-08 33.8 9.7 1.8 1 1 0 1 1 1 1 Mycothiol maleylpyruvate isomerase N-terminal domain MDMPI_C PF07398.11 ABK73171.1 - 2.1e-06 28.5 2.7 2.1e-06 28.5 2.7 1.8 2 1 0 2 2 2 1 MDMPI C-terminal domain MARVEL PF01284.23 ABK73173.1 - 0.00014 21.9 6.5 0.00014 21.9 6.5 1.7 1 1 1 2 2 2 1 Membrane-associating domain DUF2339 PF10101.9 ABK73173.1 - 0.0029 16.3 12.7 0.0037 15.9 12.7 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) SLATT_1 PF18181.1 ABK73173.1 - 0.012 15.5 2.5 0.012 15.5 2.5 2.4 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 DAP10 PF07213.11 ABK73173.1 - 0.94 9.5 5.3 2.5 8.1 1.1 2.5 2 0 0 2 2 2 0 DAP10 membrane protein DUF4131 PF13567.6 ABK73173.1 - 3.6 7.2 8.8 5.9 6.5 1.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) FA_desaturase PF00487.24 ABK73173.1 - 7.2 6.4 7.7 5.4 6.8 6.3 1.4 1 1 0 1 1 1 0 Fatty acid desaturase Acyl-CoA_dh_2 PF08028.11 ABK73174.1 - 1.6e-43 148.2 7.2 2.6e-43 147.5 7.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.24 ABK73174.1 - 6.6e-07 29.7 3.6 3.9e-06 27.1 2.4 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK73174.1 - 0.1 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain Y_phosphatase3 PF13350.6 ABK73175.1 - 1e-57 195.8 0.0 1.2e-57 195.6 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family MCR_alpha PF02249.17 ABK73175.1 - 0.03 14.7 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 2 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain Y_phosphatase PF00102.27 ABK73175.1 - 0.095 12.3 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Peripla_BP_4 PF13407.6 ABK73175.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein domain CBFD_NFYB_HMF PF00808.23 ABK73175.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TetR_N PF00440.23 ABK73175.1 - 0.11 12.3 0.0 11 5.9 0.0 2.9 2 1 1 3 3 3 0 Bacterial regulatory proteins, tetR family Peptidase_S9 PF00326.21 ABK73177.1 - 6.7e-07 29.0 0.0 1.4e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 ABK73177.1 - 4.1e-06 26.6 0.5 8.8e-06 25.5 0.4 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold UPF0227 PF05728.12 ABK73177.1 - 4.5e-05 23.5 0.0 0.00014 21.9 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) Hydrolase_4 PF12146.8 ABK73177.1 - 6.3e-05 22.3 0.0 0.00019 20.8 0.0 1.8 1 1 1 2 2 2 1 Serine aminopeptidase, S33 DUF2048 PF09752.9 ABK73177.1 - 0.00085 18.5 0.0 0.0018 17.4 0.0 1.5 1 0 0 1 1 1 1 Abhydrolase domain containing 18 PhoPQ_related PF10142.9 ABK73177.1 - 0.0019 16.9 0.0 0.0045 15.7 0.0 1.5 2 0 0 2 2 2 1 PhoPQ-activated pathogenicity-related protein AXE1 PF05448.12 ABK73177.1 - 0.0032 16.2 0.0 0.0058 15.3 0.0 1.5 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 ABK73177.1 - 0.029 14.3 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 ABK73177.1 - 0.079 12.5 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) HEPN_RnaseLS PF18869.1 ABK73177.1 - 0.19 11.8 0.1 0.41 10.8 0.1 1.5 2 0 0 2 2 2 0 RnaseLS-like HEPN PRiA4_ORF3 PF07929.11 ABK73178.1 - 2.1e-51 174.1 0.0 2.5e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein POR PF01558.18 ABK73179.1 - 7.6e-21 75.0 0.3 1.7e-20 73.8 0.3 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase TPP_enzyme_C PF02775.21 ABK73179.1 - 2.2e-05 24.3 0.4 4.5e-05 23.3 0.4 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_C PF02780.20 ABK73179.1 - 0.085 12.7 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 Transketolase, C-terminal domain MlaE PF02405.16 ABK73180.1 - 4.9e-51 173.4 29.4 6.1e-51 173.1 29.4 1.1 1 0 0 1 1 1 1 Permease MlaE adh_short_C2 PF13561.6 ABK73181.1 - 2e-45 155.2 1.3 2.8e-45 154.7 1.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK73181.1 - 1.2e-33 116.3 0.1 1.4e-33 116.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 ABK73181.1 - 1.1e-07 31.9 0.3 1.6e-07 31.4 0.3 1.2 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 ABK73181.1 - 7.8e-05 22.7 0.0 0.00024 21.1 0.0 1.8 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 ABK73181.1 - 0.002 18.2 0.2 0.006 16.6 0.2 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 ABK73181.1 - 0.0059 17.2 0.1 0.017 15.7 0.1 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 ABK73181.1 - 0.022 15.0 0.0 0.06 13.6 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain HEM4 PF02602.15 ABK73181.1 - 0.026 13.9 0.3 0.06 12.7 0.3 1.6 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD Epimerase PF01370.21 ABK73181.1 - 0.072 12.5 0.0 0.2 11.1 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family LytR_C PF13399.6 ABK73181.1 - 1.8 9.6 4.6 4 8.5 1.8 2.8 2 2 1 3 3 3 0 LytR cell envelope-related transcriptional attenuator AA_permease_2 PF13520.6 ABK73182.1 - 3.7e-55 187.5 45.6 4.9e-55 187.1 45.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ABK73182.1 - 2.2e-38 132.1 41.2 2.8e-38 131.7 41.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 ABK73182.1 - 4.9e-20 71.3 6.7 4.9e-20 71.3 6.7 4.2 5 0 0 5 5 5 1 C-terminus of AA_permease Lactamase_B PF00753.27 ABK73183.1 - 4.8e-09 36.5 1.1 6.8e-09 36.0 1.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily ICL PF00463.21 ABK73184.1 - 1.1e-122 410.3 0.0 6.2e-72 242.8 0.0 2.0 1 1 1 2 2 2 2 Isocitrate lyase family PEP_mutase PF13714.6 ABK73184.1 - 1.3e-10 41.1 0.0 3.8e-10 39.6 0.0 1.8 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Glycos_transf_4 PF00953.21 ABK73185.1 - 3.9e-38 130.9 11.6 3.9e-38 130.9 11.6 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 4 MraY_sig1 PF10555.9 ABK73185.1 - 3.5e-05 23.1 0.1 3.5e-05 23.1 0.1 2.4 3 0 0 3 3 3 1 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 AMP-binding PF00501.28 ABK73186.1 - 1e-44 152.8 0.0 2e-44 151.9 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK73186.1 - 5.2e-18 65.8 0.3 1.9e-17 64.0 0.3 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MerR PF00376.23 ABK73188.1 - 2.1e-13 49.8 0.0 6.5e-13 48.2 0.0 1.9 2 0 0 2 2 2 1 MerR family regulatory protein MerR_1 PF13411.6 ABK73188.1 - 6.2e-10 39.0 0.0 8.8e-09 35.3 0.0 2.4 2 0 0 2 2 2 1 MerR HTH family regulatory protein MerR_2 PF13591.6 ABK73188.1 - 0.0018 18.1 0.0 2.4 8.1 0.0 2.8 2 1 0 2 2 2 2 MerR HTH family regulatory protein Na_H_antiport_1 PF06965.12 ABK73189.1 - 2.6e-132 441.2 30.5 3.1e-132 441.0 30.5 1.0 1 0 0 1 1 1 1 Na+/H+ antiporter 1 DUF3953 PF13129.6 ABK73189.1 - 0.045 13.5 0.6 0.89 9.4 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3953) DUF347 PF03988.12 ABK73190.1 - 0.2 11.9 1.3 0.69 10.2 0.2 2.0 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) CAP_N PF01213.19 ABK73190.1 - 1.6 8.2 6.6 1.7 8.1 6.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal MarR_2 PF12802.7 ABK73191.1 - 1.6e-11 43.9 1.6 1.8e-11 43.7 0.4 1.8 2 0 0 2 2 2 1 MarR family TrmB PF01978.19 ABK73191.1 - 4.1e-06 26.6 0.0 6.7e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Replic_Relax PF13814.6 ABK73191.1 - 4.3e-06 26.9 0.2 5.3e-06 26.6 0.2 1.1 1 0 0 1 1 1 1 Replication-relaxation HTH_20 PF12840.7 ABK73191.1 - 8.1e-06 25.8 0.1 1.7e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.22 ABK73191.1 - 1.4e-05 24.9 0.0 2.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 ABK73191.1 - 7.3e-05 23.2 0.0 0.00012 22.5 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HxlR PF01638.17 ABK73191.1 - 0.0032 17.3 0.0 0.0051 16.6 0.0 1.3 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_28 PF13518.6 ABK73191.1 - 0.0036 17.4 0.0 0.0071 16.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Rrf2 PF02082.20 ABK73191.1 - 0.0044 17.3 0.0 0.0073 16.6 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator HTH_24 PF13412.6 ABK73191.1 - 0.0063 16.0 0.0 0.015 14.8 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 ABK73191.1 - 0.013 15.4 0.6 0.022 14.8 0.1 1.9 2 1 0 2 2 2 0 Crp-like helix-turn-helix domain DUF1323 PF07037.11 ABK73191.1 - 0.056 13.8 0.0 0.11 12.9 0.0 1.4 1 1 0 1 1 1 0 Putative transcription regulator (DUF1323) HTH_AsnC-type PF13404.6 ABK73191.1 - 0.06 13.2 0.8 0.15 11.9 0.1 2.0 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_23 PF13384.6 ABK73191.1 - 0.11 12.4 1.0 0.54 10.1 0.0 2.4 3 0 0 3 3 3 0 Homeodomain-like domain TerB_C PF15615.6 ABK73191.1 - 0.13 12.5 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 TerB-C domain ABC_tran PF00005.27 ABK73192.1 - 2.4e-32 112.3 0.0 2.9e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK73192.1 - 2.7e-08 34.0 0.3 0.00021 21.2 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK73192.1 - 6.9e-06 25.7 0.1 0.021 14.2 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ABK73192.1 - 0.0007 20.0 0.5 0.0034 17.8 0.5 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 ABK73192.1 - 0.0048 16.6 1.8 0.027 14.2 0.1 2.4 2 1 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 ABK73192.1 - 0.017 15.7 0.0 0.026 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 ABK73192.1 - 0.079 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain MMR_HSR1 PF01926.23 ABK73192.1 - 0.13 12.3 0.0 0.35 11.0 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_15 PF13175.6 ABK73192.1 - 0.28 10.8 0.0 0.44 10.2 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Cupin_2 PF07883.11 ABK73193.1 - 5.3e-07 29.3 0.1 1.3e-06 28.0 0.1 1.6 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 ABK73193.1 - 0.061 13.0 0.1 0.088 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_1 PF00190.22 ABK73193.1 - 0.094 12.3 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Cupin CbtA PF09490.10 ABK73194.1 - 9.5e-75 251.5 17.8 1.1e-74 251.3 17.8 1.0 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtA) DUF1129 PF06570.11 ABK73194.1 - 0.16 11.4 3.0 0.36 10.3 2.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) DUF1772 PF08592.11 ABK73194.1 - 2.8 8.3 19.0 2.5 8.4 0.0 3.6 1 1 3 4 4 4 0 Domain of unknown function (DUF1772) Phage_holin_3_6 PF07332.11 ABK73194.1 - 6.7 6.8 31.6 0.052 13.6 8.0 3.6 3 1 1 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III PMSR PF01625.21 ABK73195.1 - 1.7e-58 197.1 0.0 2e-58 196.9 0.0 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase F420H2_quin_red PF04075.14 ABK73196.1 - 0.00029 21.0 0.1 0.00035 20.7 0.1 1.2 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase MMPL PF03176.15 ABK73197.1 - 1.4e-206 684.9 33.4 2.3e-108 362.1 4.9 3.3 3 1 0 4 4 4 2 MMPL family DUF3168 PF11367.8 ABK73197.1 - 0.054 13.7 1.0 0.15 12.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3168) Sec34 PF04136.15 ABK73197.1 - 0.09 12.7 0.6 0.19 11.6 0.6 1.5 1 0 0 1 1 1 0 Sec34-like family DUF2748 PF10871.8 ABK73197.1 - 0.22 10.1 0.4 0.38 9.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2748) DUF1664 PF07889.12 ABK73197.1 - 0.38 10.8 2.0 0.67 10.0 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DDE_Tnp_1_4 PF13701.6 ABK73198.1 - 9.5e-69 231.7 0.0 1.1e-68 231.5 0.0 1.0 1 0 0 1 1 1 1 Transposase DDE domain group 1 DDE_Tnp_1 PF01609.21 ABK73198.1 - 0.0011 18.6 0.0 0.0021 17.7 0.0 1.5 1 1 0 1 1 1 1 Transposase DDE domain ABC_tran PF00005.27 ABK73199.1 - 1.3e-23 84.0 0.0 1.8e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter BCA_ABC_TP_C PF12399.8 ABK73199.1 - 3.4e-11 42.8 0.4 8.2e-11 41.6 0.4 1.7 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_21 PF13304.6 ABK73199.1 - 2.2e-08 34.3 0.1 2.9e-05 24.0 0.1 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ABK73199.1 - 1.1e-06 28.2 0.1 3.5e-06 26.7 0.2 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 ABK73199.1 - 1.7e-05 24.4 0.0 7.3e-05 22.3 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ABK73199.1 - 2.1e-05 25.1 0.1 2.7e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_27 PF13514.6 ABK73199.1 - 0.0036 16.9 0.0 0.0057 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ABK73199.1 - 0.0036 17.0 1.3 0.0092 15.7 1.3 1.7 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 ABK73199.1 - 0.0056 16.4 0.0 0.0073 16.0 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 ABK73199.1 - 0.014 15.8 0.2 0.045 14.2 0.2 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 ABK73199.1 - 0.02 15.1 0.1 0.12 12.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ABK73199.1 - 0.055 13.9 0.2 0.15 12.4 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 ABK73199.1 - 0.057 13.7 0.1 0.5 10.6 0.1 2.3 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 ABK73199.1 - 0.087 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Mg_chelatase PF01078.21 ABK73199.1 - 0.096 12.1 0.0 0.23 10.8 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF1794 PF08768.11 ABK73200.1 - 3.2e-18 66.1 0.0 4.1e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) Lyase_1 PF00206.20 ABK73202.1 - 7.3e-23 81.4 0.3 2.4e-22 79.7 0.1 1.9 2 1 0 2 2 2 1 Lyase ADSL_C PF10397.9 ABK73202.1 - 2e-13 50.6 2.3 4.8e-13 49.4 0.4 2.6 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus AI-2E_transport PF01594.16 ABK73203.1 - 2.3e-72 243.9 27.1 2.6e-72 243.7 27.1 1.0 1 0 0 1 1 1 1 AI-2E family transporter DUF3938 PF13074.6 ABK73203.1 - 0.15 12.4 1.0 4.7 7.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) Cyclase PF04199.13 ABK73204.1 - 1.1e-37 129.3 0.0 1.5e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase CoA_transf_3 PF02515.17 ABK73205.1 - 7.2e-122 407.0 0.2 8.3e-122 406.8 0.2 1.0 1 0 0 1 1 1 1 CoA-transferase family III tRNA_m1G_MT PF01746.21 ABK73206.1 - 1.7e-71 240.0 0.0 1.9e-71 239.8 0.0 1.0 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase p450 PF00067.22 ABK73207.1 - 2.3e-16 59.6 0.0 4.7e-13 48.7 0.0 3.0 3 0 0 3 3 3 3 Cytochrome P450 SDH_alpha PF03313.15 ABK73208.1 - 1.6e-99 332.8 0.2 1.6e-99 332.8 0.2 1.4 2 0 0 2 2 2 1 Serine dehydratase alpha chain SDH_beta PF03315.15 ABK73208.1 - 1.1e-55 188.3 0.1 2.1e-55 187.3 0.1 1.5 1 0 0 1 1 1 1 Serine dehydratase beta chain MmgE_PrpD PF03972.14 ABK73208.1 - 0.15 10.6 2.3 0.23 10.0 2.3 1.2 1 0 0 1 1 1 0 MmgE/PrpD family NTP_transferase PF00483.23 ABK73209.1 - 3.4e-26 92.3 0.0 4.4e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 ABK73209.1 - 4.1e-06 27.2 3.6 8.5e-06 26.2 3.6 1.8 1 1 0 1 1 1 1 MobA-like NTP transferase domain Imm75 PF15660.6 ABK73209.1 - 0.019 15.2 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 Putative Immunity protein 75 AAA PF00004.29 ABK73210.1 - 1.3e-54 184.1 0.0 3.1e-39 134.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ABK73210.1 - 8.9e-17 60.6 9.7 3.5e-09 36.3 3.6 2.5 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 ABK73210.1 - 1.1e-13 51.2 0.0 8.7e-13 48.3 0.0 2.3 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain AAA_16 PF13191.6 ABK73210.1 - 2.5e-09 37.8 5.7 0.00024 21.5 0.1 3.9 2 2 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 ABK73210.1 - 3.6e-06 27.0 0.2 0.0014 18.7 0.0 3.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 ABK73210.1 - 1.7e-05 25.3 0.0 0.018 15.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 ABK73210.1 - 2.4e-05 24.1 0.0 0.14 11.9 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ABK73210.1 - 4.1e-05 23.9 0.4 0.13 12.6 0.0 3.7 3 2 1 4 4 3 1 AAA domain AAA_33 PF13671.6 ABK73210.1 - 7.2e-05 23.0 0.0 0.29 11.3 0.0 2.7 3 0 0 3 3 2 2 AAA domain Rad17 PF03215.15 ABK73210.1 - 0.00019 21.4 0.1 0.15 11.9 0.0 2.2 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_30 PF13604.6 ABK73210.1 - 0.00024 20.9 0.1 0.53 10.0 0.1 2.9 2 0 0 2 2 2 2 AAA domain Molydop_binding PF01568.21 ABK73210.1 - 0.0003 20.8 0.1 0.00098 19.1 0.1 1.9 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain AAA_2 PF07724.14 ABK73210.1 - 0.00036 20.7 0.0 0.0075 16.4 0.0 2.5 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 ABK73210.1 - 0.00051 20.3 1.1 0.022 15.0 0.0 2.9 3 0 0 3 3 2 1 AAA domain Adeno_IVa2 PF02456.15 ABK73210.1 - 0.00059 18.7 0.0 0.25 10.1 0.0 2.2 2 0 0 2 2 2 2 Adenovirus IVa2 protein Sigma54_activ_2 PF14532.6 ABK73210.1 - 0.00062 19.9 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain RNA_helicase PF00910.22 ABK73210.1 - 0.00078 19.8 0.0 0.22 12.0 0.0 2.4 2 0 0 2 2 2 1 RNA helicase TsaE PF02367.17 ABK73210.1 - 0.0013 18.7 0.0 2 8.5 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 ABK73210.1 - 0.0013 18.5 0.0 0.046 13.5 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 ABK73210.1 - 0.0014 18.6 0.0 0.033 14.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 ABK73210.1 - 0.0022 18.3 0.1 2.4 8.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 ABK73210.1 - 0.0033 17.0 1.3 0.12 11.9 0.2 3.3 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 ABK73210.1 - 0.0034 17.3 0.3 2 8.3 0.0 3.1 3 0 0 3 3 3 1 NACHT domain AAA_7 PF12775.7 ABK73210.1 - 0.0065 16.0 0.1 1.3 8.5 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 ABK73210.1 - 0.0077 16.0 0.0 0.35 10.6 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_29 PF13555.6 ABK73210.1 - 0.0082 15.9 0.0 1.4 8.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.13 ABK73210.1 - 0.0082 15.3 0.0 3.3 6.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ATPase_2 PF01637.18 ABK73210.1 - 0.0089 16.0 0.0 1.6 8.6 0.0 2.2 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 ABK73210.1 - 0.011 15.5 0.0 0.93 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 ABK73210.1 - 0.015 15.0 0.0 14 5.4 0.0 3.5 2 1 1 3 3 3 0 Sigma-54 interaction domain NTPase_1 PF03266.15 ABK73210.1 - 0.018 15.0 0.0 0.98 9.3 0.0 2.8 3 0 0 3 3 3 0 NTPase AAA_11 PF13086.6 ABK73210.1 - 0.022 14.6 0.0 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 ABK73210.1 - 0.028 15.0 0.0 3.2 8.3 0.0 2.5 2 0 0 2 2 2 0 ABC transporter Mg_chelatase PF01078.21 ABK73210.1 - 0.031 13.7 0.7 0.56 9.6 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 ABK73210.1 - 0.057 13.3 0.0 7.9 6.4 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase NB-ARC PF00931.22 ABK73210.1 - 0.11 11.6 0.0 4.6 6.4 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AFG1_ATPase PF03969.16 ABK73210.1 - 0.18 10.7 0.2 8 5.2 0.0 2.5 2 1 0 2 2 2 0 AFG1-like ATPase ATP_bind_1 PF03029.17 ABK73210.1 - 0.2 11.4 0.2 2.4 7.9 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein cobW PF02492.19 ABK73210.1 - 0.22 11.1 0.2 8.9 5.9 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ECH_1 PF00378.20 ABK73211.1 - 2.9e-49 167.6 0.0 3.3e-49 167.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK73211.1 - 2.4e-27 96.3 0.1 3.3e-27 95.9 0.1 1.2 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase SpoVS PF04232.12 ABK73211.1 - 0.04 13.6 0.9 0.071 12.9 0.9 1.4 1 0 0 1 1 1 0 Stage V sporulation protein S (SpoVS) TetR_C_14 PF17754.1 ABK73211.1 - 0.22 11.5 6.5 0.27 11.2 5.3 1.7 1 1 1 2 2 2 0 MftR C-terminal domain Cys_Met_Meta_PP PF01053.20 ABK73212.1 - 6.5e-81 271.8 0.0 1.3e-80 270.8 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 ABK73212.1 - 0.0034 16.8 0.0 0.0057 16.0 0.0 1.5 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 ABK73212.1 - 0.039 12.9 0.1 0.22 10.4 0.0 2.0 1 1 1 2 2 2 0 Aminotransferase class-V Beta_elim_lyase PF01212.21 ABK73212.1 - 0.039 13.2 0.0 0.12 11.6 0.0 1.8 1 1 0 1 1 1 0 Beta-eliminating lyase Met_gamma_lyase PF06838.11 ABK73212.1 - 0.12 10.9 0.0 0.32 9.5 0.0 1.6 2 0 0 2 2 2 0 Methionine gamma-lyase Glyco_trans_4_5 PF16994.5 ABK73212.1 - 0.22 11.1 0.0 0.57 9.8 0.0 1.6 1 1 0 1 1 1 0 Glycosyl-transferase family 4 Glycos_transf_2 PF00535.26 ABK73213.1 - 3.6e-18 65.9 0.0 5.2e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ABK73213.1 - 4.5e-16 59.4 0.0 1.6e-15 57.6 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ABK73213.1 - 2.3e-06 27.7 0.2 3.2e-06 27.2 0.2 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 ABK73213.1 - 1.8e-05 24.3 0.0 0.00016 21.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 ABK73213.1 - 0.0015 18.1 0.0 0.0036 16.8 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 ABK73213.1 - 0.0037 16.9 0.1 0.0066 16.1 0.1 1.3 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase AAA_3 PF07726.11 ABK73214.1 - 7.3e-63 210.3 0.0 1.1e-62 209.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF58 PF01882.18 ABK73214.1 - 1.6e-17 63.6 0.4 5.2e-17 61.9 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function DUF58 AAA_5 PF07728.14 ABK73214.1 - 4.3e-12 46.2 0.0 9.7e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 ABK73214.1 - 0.00027 20.7 0.0 0.00082 19.1 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 ABK73214.1 - 0.0034 17.8 0.0 0.0085 16.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 ABK73214.1 - 0.01 15.6 0.0 0.038 13.7 0.0 1.9 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain MCM PF00493.23 ABK73214.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain Mg_chelatase PF01078.21 ABK73214.1 - 0.065 12.6 0.1 7 6.0 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Peptidase_M20 PF01546.28 ABK73215.1 - 8.2e-24 84.5 1.3 1.2e-23 83.9 1.3 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF308 PF03729.13 ABK73216.1 - 0.0027 18.0 11.5 0.0028 17.9 11.5 1.0 1 0 0 1 1 1 1 Short repeat of unknown function (DUF308) DUF3488 PF11992.8 ABK73216.1 - 0.074 12.0 0.5 0.071 12.0 0.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) DUF3185 PF11381.8 ABK73216.1 - 0.23 11.5 16.0 0.65 10.0 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) DUF3955 PF13127.6 ABK73216.1 - 1.8 8.5 11.0 0.5 10.2 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3955) TMEM238 PF15125.6 ABK73216.1 - 2 8.7 13.7 2.7 8.2 13.7 1.3 1 0 0 1 1 1 0 TMEM238 protein family DUF973 PF06157.11 ABK73216.1 - 2.4 7.1 10.8 2.5 7.1 10.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF3784 PF12650.7 ABK73216.1 - 2.5 8.4 9.6 2.9 8.1 9.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) DUF5362 PF17319.2 ABK73216.1 - 2.7 7.9 12.0 5.5 6.9 12.0 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5362) DUF2892 PF11127.8 ABK73216.1 - 5.3 7.2 10.6 7.8 6.6 10.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2892) G0-G1_switch_2 PF15103.6 ABK73216.1 - 7.3 7.1 5.7 2.9 8.3 3.3 1.6 1 1 1 2 2 2 0 G0/G1 switch protein 2 Neurensin PF14927.6 ABK73216.1 - 7.7 6.2 9.3 6.1 6.6 0.8 2.0 1 1 1 2 2 2 0 Neurensin DUF2905 PF11146.8 ABK73216.1 - 9.7 6.5 13.9 2.9 8.1 4.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2905) Septum_form PF13845.6 ABK73217.1 - 2.5e-79 266.0 0.0 3.6e-79 265.5 0.0 1.2 1 0 0 1 1 1 1 Septum formation SPX PF03105.19 ABK73217.1 - 3.8 7.3 9.8 5 6.9 9.8 1.2 1 0 0 1 1 1 0 SPX domain COXG PF06240.13 ABK73218.1 - 9e-20 70.9 0.0 1.3e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Carbon monoxide dehydrogenase subunit G (CoxG) Polyketide_cyc2 PF10604.9 ABK73218.1 - 3.8e-07 30.5 0.3 5.2e-07 30.0 0.3 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 ABK73218.1 - 0.0034 17.6 0.0 0.0045 17.2 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc PF03364.20 ABK73218.1 - 0.0047 17.1 0.1 0.0094 16.2 0.1 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport ABATE PF07336.11 ABK73218.1 - 0.2 12.3 8.6 0.43 11.2 7.2 2.2 1 1 1 2 2 2 0 Putative stress-induced transcription regulator NUDIX PF00293.28 ABK73219.1 - 6.6e-06 26.2 1.0 0.0077 16.3 0.2 2.8 2 1 0 2 2 2 2 NUDIX domain D-ser_dehydrat PF14031.6 ABK73220.1 - 4.6e-19 68.9 0.0 3.3e-18 66.1 0.0 2.4 3 0 0 3 3 3 1 Putative serine dehydratase domain Ald_Xan_dh_C2 PF02738.18 ABK73221.1 - 7.4e-148 493.4 0.4 8.7e-148 493.2 0.4 1.0 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 ABK73221.1 - 5e-32 110.5 0.0 9.5e-32 109.6 0.0 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Methyltransf_7 PF03492.15 ABK73223.1 - 4.6e-29 101.7 0.0 5.8e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 SAM dependent carboxyl methyltransferase Ribosomal_L6 PF00347.23 ABK73224.1 - 8.9e-42 141.6 0.3 9.8e-21 74.2 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 TubC_N PF18563.1 ABK73224.1 - 0.0048 16.9 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 TubC N-terminal docking domain Inositol_P PF00459.25 ABK73225.1 - 1.1e-35 123.5 0.4 6.9e-35 120.9 0.4 1.8 1 1 0 1 1 1 1 Inositol monophosphatase family GDP_Man_Dehyd PF16363.5 ABK73226.1 - 2.2e-60 204.8 0.0 4.2e-60 203.9 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ABK73226.1 - 4.4e-54 183.5 0.0 5.1e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ABK73226.1 - 1.8e-17 63.3 0.0 2.3e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ABK73226.1 - 6.5e-15 55.0 0.0 7e-14 51.6 0.0 2.0 1 1 1 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 ABK73226.1 - 5.9e-11 42.0 0.0 1.2e-10 41.0 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 ABK73226.1 - 1.6e-10 40.6 0.1 2.3e-08 33.5 0.1 2.4 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 ABK73226.1 - 1.8e-08 34.5 0.0 2.6e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 ABK73226.1 - 0.00021 20.8 0.4 0.0011 18.5 0.0 2.1 2 1 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 ABK73226.1 - 0.04 13.5 0.2 0.089 12.3 0.2 1.6 1 1 0 1 1 1 0 NmrA-like family KR PF08659.10 ABK73226.1 - 0.05 13.5 0.2 0.14 12.0 0.2 1.7 1 1 0 1 1 1 0 KR domain YgbB PF02542.16 ABK73227.1 - 3.8e-46 157.2 0.0 4.4e-46 157.0 0.0 1.0 1 0 0 1 1 1 1 YgbB family MDMPI_N PF11716.8 ABK73228.1 - 1.5e-24 87.3 9.3 1.5e-24 87.3 9.3 1.6 2 0 0 2 2 2 1 Mycothiol maleylpyruvate isomerase N-terminal domain MDMPI_C PF07398.11 ABK73228.1 - 1.3e-17 64.4 4.9 1.3e-17 64.4 4.9 2.5 2 1 0 2 2 2 1 MDMPI C-terminal domain DinB_2 PF12867.7 ABK73228.1 - 0.04 14.4 1.7 0.1 13.1 1.7 1.9 1 1 0 1 1 1 0 DinB superfamily His_Phos_1 PF00300.22 ABK73229.1 - 5.4e-40 137.2 0.7 6.7e-40 136.9 0.7 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PALB2_WD40 PF16756.5 ABK73229.1 - 0.018 14.0 0.1 0.027 13.4 0.1 1.2 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain Peptidase_S11 PF00768.20 ABK73230.1 - 5.1e-39 134.2 0.0 6.6e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 ABK73230.1 - 1.5e-09 37.8 0.0 1.9e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase enzyme family Peptidase_S13 PF02113.15 ABK73230.1 - 2e-05 23.5 0.0 3e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 D-Ala-D-Ala carboxypeptidase 3 (S13) family Acyl-CoA_dh_1 PF00441.24 ABK73231.1 - 7.7e-49 165.7 3.9 1.3e-48 165.0 3.9 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK73231.1 - 3.6e-31 108.2 0.1 7e-31 107.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ABK73231.1 - 1.9e-30 104.9 0.0 4.2e-30 103.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ABK73231.1 - 9.7e-27 93.9 3.6 9.7e-27 93.9 3.6 2.1 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB PF03241.13 ABK73231.1 - 0.0093 15.1 0.1 0.019 14.0 0.1 1.5 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase C terminal PucR PF07905.11 ABK73231.1 - 0.11 12.7 0.5 0.57 10.5 0.1 2.2 2 0 0 2 2 2 0 Purine catabolism regulatory protein-like family GerE PF00196.19 ABK73232.1 - 5e-12 45.2 0.0 7.6e-12 44.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 ABK73232.1 - 7.3e-05 22.4 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 ABK73232.1 - 0.0031 17.0 0.2 0.015 14.8 0.0 2.2 3 0 0 3 3 3 1 Sigma-70, region 4 HTH_29 PF13551.6 ABK73232.1 - 0.013 15.5 0.5 4.2 7.5 0.1 3.1 2 1 1 3 3 3 0 Winged helix-turn helix DUF742 PF05331.11 ABK73232.1 - 0.053 13.3 0.1 0.082 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF742) Response_reg PF00072.24 ABK73232.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Response regulator receiver domain HTH_5 PF01022.20 ABK73232.1 - 0.14 12.1 0.0 12 5.8 0.0 2.3 1 1 1 2 2 2 0 Bacterial regulatory protein, arsR family BPD_transp_1 PF00528.22 ABK73233.1 - 1.9e-18 66.9 15.8 1.9e-18 66.9 15.8 2.0 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component His_Phos_1 PF00300.22 ABK73234.1 - 1.5e-35 122.7 0.1 9.1e-33 113.6 0.1 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ABC_tran PF00005.27 ABK73235.1 - 2.6e-37 128.4 0.0 3.5e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK73235.1 - 1.2e-09 38.5 0.0 0.0007 19.5 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK73235.1 - 9.1e-08 31.8 0.0 3.9e-05 23.2 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 ABK73235.1 - 2.1e-05 24.5 0.1 4.2e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 ABK73235.1 - 5.5e-05 23.5 0.1 0.00021 21.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ABK73235.1 - 0.00011 22.6 0.4 0.00023 21.6 0.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.9 ABK73235.1 - 0.0003 19.7 0.4 0.63 8.8 0.1 2.8 2 1 0 2 2 2 2 Predicted ATPase of the ABC class AAA_13 PF13166.6 ABK73235.1 - 0.00039 19.2 0.0 0.027 13.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ABK73235.1 - 0.00052 20.2 0.8 0.0025 18.0 0.8 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ABK73235.1 - 0.00093 18.9 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 ABK73235.1 - 0.0023 17.7 0.0 0.0023 17.7 0.0 2.3 3 1 0 3 3 2 1 AAA domain AAA_28 PF13521.6 ABK73235.1 - 0.0032 17.7 1.1 0.0066 16.7 0.1 2.0 2 1 0 2 2 2 1 AAA domain TniB PF05621.11 ABK73235.1 - 0.0034 16.8 0.0 2.2 7.7 0.0 2.2 2 0 0 2 2 2 2 Bacterial TniB protein AAA_24 PF13479.6 ABK73235.1 - 0.0055 16.5 0.0 0.0086 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 ABK73235.1 - 0.0066 16.0 0.1 0.038 13.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 ABK73235.1 - 0.01 16.4 0.0 0.015 15.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 ABK73235.1 - 0.01 15.4 1.1 0.02 14.5 0.3 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 ABK73235.1 - 0.012 15.6 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_18 PF13238.6 ABK73235.1 - 0.012 16.2 0.1 0.036 14.6 0.1 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ABK73235.1 - 0.014 15.4 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ATP-synt_ab PF00006.25 ABK73235.1 - 0.014 15.0 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain TsaE PF02367.17 ABK73235.1 - 0.015 15.3 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 ABK73235.1 - 0.017 14.9 0.0 0.042 13.6 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 ABK73235.1 - 0.017 15.1 0.1 0.043 13.8 0.1 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 ABK73235.1 - 0.026 14.9 0.5 0.55 10.7 0.1 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 ABK73235.1 - 0.051 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein SbcCD_C PF13558.6 ABK73235.1 - 0.051 13.8 0.4 1 9.7 0.4 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Roc PF08477.13 ABK73235.1 - 0.059 13.6 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 ABK73235.1 - 0.077 13.3 0.9 0.36 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 ABK73235.1 - 0.082 12.7 0.0 1.3 8.7 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 ABK73235.1 - 0.11 11.7 0.0 0.23 10.6 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_7 PF12775.7 ABK73235.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_15 PF13175.6 ABK73235.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 ABK73235.1 - 0.16 12.1 0.1 0.38 10.8 0.0 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase SRP54 PF00448.22 ABK73235.1 - 0.16 11.6 0.7 0.31 10.6 0.1 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_14 PF13173.6 ABK73235.1 - 0.17 12.0 0.0 0.46 10.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_PrkA PF08298.11 ABK73235.1 - 0.17 10.8 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain ATPase_2 PF01637.18 ABK73235.1 - 0.2 11.5 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF3817 PF12823.7 ABK73236.1 - 2.6e-19 69.8 7.2 3.6e-19 69.4 7.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3817) MARVEL PF01284.23 ABK73236.1 - 0.11 12.6 5.0 0.13 12.3 5.0 1.1 1 0 0 1 1 1 0 Membrane-associating domain MaoC_dehydratas PF01575.19 ABK73237.1 - 5.3e-24 84.1 0.1 2.7e-22 78.6 0.0 2.3 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.6 ABK73237.1 - 1.4e-05 25.2 0.2 0.065 13.4 0.0 2.4 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase Cas9_a PF18470.1 ABK73237.1 - 0.011 15.3 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Cas9 alpha-helical lobe domain 2-oxoacid_dh PF00198.23 ABK73238.1 - 9.2e-72 241.2 0.0 1.7e-71 240.4 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 ABK73238.1 - 3.8e-43 145.2 11.3 1.3e-21 76.2 1.0 2.9 3 0 0 3 3 3 2 Biotin-requiring enzyme E3_binding PF02817.17 ABK73238.1 - 4.4e-16 58.9 0.3 4.4e-16 58.9 0.3 2.1 2 0 0 2 2 1 1 e3 binding domain Trypan_PARP PF05887.11 ABK73238.1 - 1.1e-10 41.6 49.6 1.4e-09 38.0 25.2 3.0 3 0 0 3 3 3 2 Procyclic acidic repetitive protein (PARP) GCV_H PF01597.19 ABK73238.1 - 4.4e-05 23.3 4.9 0.067 13.1 0.2 3.4 3 0 0 3 3 3 2 Glycine cleavage H-protein TonB_N PF16031.5 ABK73238.1 - 5.4e-05 23.7 31.4 5.4e-05 23.7 31.4 3.6 3 0 0 3 3 3 2 TonB polyproline region HlyD_3 PF13437.6 ABK73238.1 - 0.0021 18.7 6.9 1.5 9.6 0.1 4.3 2 2 2 4 4 4 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 ABK73238.1 - 0.003 17.3 4.5 4.2 7.3 0.0 4.3 2 2 2 4 4 4 1 Biotin-lipoyl like PTS_EIIA_1 PF00358.20 ABK73238.1 - 0.036 13.8 0.6 14 5.5 0.0 3.0 2 1 1 3 3 3 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 PYNP_C PF07831.13 ABK73238.1 - 0.077 12.7 0.8 5.9 6.6 0.0 3.3 3 1 0 3 3 3 0 Pyrimidine nucleoside phosphorylase C-terminal domain HlyD_2 PF12700.7 ABK73238.1 - 0.16 10.7 0.0 4.1 6.0 0.0 2.1 2 0 0 2 2 2 0 HlyD family secretion protein Amidohydro_2 PF04909.14 ABK73240.1 - 2.8e-30 106.1 0.8 3.7e-30 105.7 0.8 1.1 1 0 0 1 1 1 1 Amidohydrolase DUF3515 PF12028.8 ABK73241.1 - 2.3e-60 202.9 2.5 2.7e-60 202.7 2.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3515) MFS_3 PF05977.13 ABK73242.1 - 9.9e-29 100.1 41.8 1.2e-28 99.8 41.8 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.16 ABK73242.1 - 1.4e-24 86.7 52.8 1.4e-24 86.7 52.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TLV_coat PF00429.19 ABK73242.1 - 0.41 9.3 1.4 0.61 8.7 1.4 1.2 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) DUF1116 PF06545.11 ABK73243.1 - 8.9e-73 244.3 0.0 1.2e-72 243.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1116) AOC_like PF18678.1 ABK73243.1 - 0.079 12.6 0.2 0.32 10.6 0.0 2.0 2 0 0 2 2 2 0 Allene oxide cyclase barrel like domain SKI PF01202.22 ABK73244.1 - 1.2e-44 152.2 0.0 1.4e-44 152.0 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 ABK73244.1 - 6.3e-07 29.6 0.0 1.5e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 ABK73244.1 - 1.6e-05 25.4 0.1 0.00044 20.7 0.0 2.4 1 1 1 2 2 2 1 AAA domain KTI12 PF08433.10 ABK73244.1 - 9.5e-05 22.0 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 ABK73244.1 - 0.00015 22.3 0.0 0.00026 21.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 ABK73244.1 - 0.0004 20.6 0.1 0.00095 19.3 0.1 1.6 1 1 1 2 2 2 1 Cytidylate kinase-like family Mg_chelatase PF01078.21 ABK73244.1 - 0.00063 19.2 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Cytidylate_kin PF02224.18 ABK73244.1 - 0.0068 16.2 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Cytidylate kinase AAA_28 PF13521.6 ABK73244.1 - 0.0084 16.4 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 ABK73244.1 - 0.015 15.3 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 ABK73244.1 - 0.016 15.7 0.0 0.043 14.2 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 ABK73244.1 - 0.017 14.9 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.18 ABK73244.1 - 0.022 14.1 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_22 PF13401.6 ABK73244.1 - 0.033 14.5 0.0 0.07 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ABK73244.1 - 0.044 13.9 0.0 0.077 13.1 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Ploopntkinase3 PF18751.1 ABK73244.1 - 0.053 13.4 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 CoaE PF01121.20 ABK73244.1 - 0.12 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase Pkinase PF00069.25 ABK73245.1 - 1.3e-39 136.1 0.0 1.8e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ABK73245.1 - 5.6e-24 84.8 0.0 7.5e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ABK73245.1 - 0.00013 20.9 0.0 0.0002 20.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ABK73245.1 - 0.00038 20.4 1.3 0.00038 20.4 1.3 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 ABK73245.1 - 0.0034 16.8 0.0 0.0057 16.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4395 PF14340.6 ABK73245.1 - 0.029 14.7 0.9 0.086 13.2 0.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4395) HTH_18 PF12833.7 ABK73246.1 - 2.2e-24 85.5 0.3 4.3e-24 84.6 0.3 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain DJ-1_PfpI PF01965.24 ABK73246.1 - 5.3e-23 81.6 0.0 8.4e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family HTH_AraC PF00165.23 ABK73246.1 - 1.2e-13 50.7 0.0 3.9e-06 26.8 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family GATase_3 PF07685.14 ABK73246.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain adh_short_C2 PF13561.6 ABK73247.1 - 3.2e-56 190.5 0.0 4.1e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK73247.1 - 7.3e-12 45.2 0.0 1e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase IFRD PF05004.13 ABK73247.1 - 0.065 12.3 0.0 0.093 11.8 0.0 1.2 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) FGGY_C PF02782.16 ABK73248.1 - 9.6e-44 149.5 0.9 1.5e-43 148.9 0.9 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 ABK73248.1 - 1.2e-11 44.6 0.0 1.1e-10 41.5 0.0 2.4 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain AnmK PF03702.14 ABK73248.1 - 0.00096 18.4 0.1 0.0017 17.5 0.1 1.3 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase Beta-lactamase PF00144.24 ABK73249.1 - 2.5e-68 230.8 2.7 3.1e-68 230.4 2.7 1.0 1 0 0 1 1 1 1 Beta-lactamase MMPL PF03176.15 ABK73250.1 - 1e-176 586.7 12.4 1.7e-94 316.4 1.0 2.4 2 0 0 2 2 2 2 MMPL family ACR_tran PF00873.19 ABK73250.1 - 0.34 8.5 20.7 0.27 8.8 4.7 2.5 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family Pox_EPC_I2-L1 PF12575.8 ABK73250.1 - 0.95 9.7 4.2 21 5.5 0.4 2.9 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 Amidohydro_1 PF01979.20 ABK73251.1 - 3.9e-23 82.3 0.0 6.7e-23 81.6 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ABK73251.1 - 7.4e-14 52.1 0.8 9.1e-07 28.7 0.0 2.7 2 1 1 3 3 3 2 Amidohydrolase family Usp PF00582.26 ABK73251.1 - 0.045 14.3 0.0 0.079 13.5 0.0 1.4 1 0 0 1 1 1 0 Universal stress protein family Sugar_tr PF00083.24 ABK73252.1 - 4.3e-30 105.0 30.2 1.1e-17 64.1 9.2 2.8 1 1 2 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 ABK73252.1 - 7.9e-29 100.7 48.3 2.6e-14 52.9 24.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ABK73252.1 - 1.3e-07 30.6 31.3 3.7e-07 29.0 16.4 2.6 1 1 1 2 2 2 2 MFS/sugar transport protein Nuc_H_symport PF03825.16 ABK73252.1 - 3.6e-05 22.9 21.4 8e-05 21.8 21.4 1.6 1 1 0 1 1 1 1 Nucleoside H+ symporter Rhamno_transf PF11316.8 ABK73252.1 - 0.072 12.5 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative rhamnosyl transferase Aminotran_1_2 PF00155.21 ABK73253.1 - 3e-59 201.0 0.0 3.8e-59 200.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 ABK73253.1 - 2.6e-10 40.1 0.6 3.8e-10 39.6 0.6 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 ABK73253.1 - 1.1e-08 34.4 0.0 1.7e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 ABK73253.1 - 3e-07 29.3 0.0 3.9e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.21 ABK73253.1 - 5.4e-05 22.0 0.0 8.3e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 ABK73253.1 - 0.0029 16.9 0.3 0.0098 15.2 0.3 1.9 1 1 0 1 1 1 1 Beta-eliminating lyase Plasmid_stab_B PF10784.9 ABK73253.1 - 0.086 12.7 2.7 0.24 11.2 0.2 2.3 2 0 0 2 2 2 0 Plasmid stability protein Fer2 PF00111.27 ABK73254.1 - 4.3e-13 49.0 0.4 7.4e-13 48.3 0.4 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.21 ABK73254.1 - 0.00055 20.6 0.3 0.31 11.7 0.2 3.1 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain Fer2_4 PF13510.6 ABK73254.1 - 0.00067 19.6 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FAD_binding_6 PF00970.24 ABK73254.1 - 0.0028 18.0 0.0 0.032 14.6 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 ABK73254.1 - 0.0048 17.0 0.0 0.085 13.0 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain HTH_Tnp_1 PF01527.20 ABK73255.1 - 0.00079 19.7 0.6 0.0018 18.5 0.6 1.6 1 1 0 1 1 1 1 Transposase DUF4407 PF14362.6 ABK73255.1 - 0.0081 15.5 2.1 0.0094 15.3 2.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Paramyx_P_V_C PF03210.13 ABK73255.1 - 0.096 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal Ribosomal_L11 PF00298.19 ABK73255.1 - 0.11 13.0 0.2 0.16 12.5 0.2 1.3 1 0 0 1 1 1 0 Ribosomal protein L11, RNA binding domain SlyX PF04102.12 ABK73255.1 - 0.12 13.0 1.1 0.28 11.8 1.1 1.7 1 1 0 1 1 1 0 SlyX DUF1192 PF06698.11 ABK73255.1 - 1.7 8.7 5.2 1.6 8.8 3.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) adh_short_C2 PF13561.6 ABK73256.1 - 7e-64 215.6 2.4 7.9e-64 215.4 2.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK73256.1 - 2.6e-51 173.9 0.1 3.1e-51 173.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK73256.1 - 8.8e-13 48.6 0.3 1.3e-12 48.0 0.3 1.2 1 0 0 1 1 1 1 KR domain Ribosomal_L11_N PF03946.14 ABK73256.1 - 0.042 13.7 1.2 0.23 11.3 0.0 2.5 2 1 1 3 3 3 0 Ribosomal protein L11, N-terminal domain Epimerase PF01370.21 ABK73256.1 - 0.045 13.2 0.1 0.051 13.0 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Bac_luciferase PF00296.20 ABK73257.1 - 1.1e-46 159.7 1.0 1.4e-46 159.3 1.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.16 ABK73259.1 - 7.7e-42 143.5 57.9 4.2e-26 91.7 22.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK73259.1 - 2.1e-07 30.2 33.6 5.3e-05 22.3 5.0 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 ABK73259.1 - 7.6e-07 28.0 12.8 7.6e-07 28.0 12.8 2.4 1 1 1 2 2 2 1 MFS/sugar transport protein Alpha-amyl_C2 PF07821.12 ABK73259.1 - 0.027 14.7 0.4 26 5.1 0.2 3.3 3 0 0 3 3 3 0 Alpha-amylase C-terminal beta-sheet domain MFS_1_like PF12832.7 ABK73259.1 - 0.03 13.2 11.3 0.031 13.1 0.6 2.7 2 1 1 3 3 3 0 MFS_1 like family adh_short_C2 PF13561.6 ABK73260.1 - 1e-57 195.4 3.6 1.3e-57 195.1 3.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK73260.1 - 1.9e-53 180.8 0.5 2.6e-53 180.4 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK73260.1 - 8.3e-15 55.1 0.4 1.1e-14 54.8 0.4 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK73260.1 - 0.00065 19.2 1.3 0.0011 18.5 0.9 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ABK73260.1 - 0.00075 19.4 4.2 0.0016 18.4 4.2 1.5 1 1 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 ABK73260.1 - 0.0041 16.5 0.0 0.0048 16.3 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) TLP1_add_C PF18313.1 ABK73260.1 - 0.026 14.5 0.5 0.93 9.5 0.3 2.5 2 0 0 2 2 2 0 Thiolase-like protein type 1 additional C-terminal domain VBS PF08913.10 ABK73260.1 - 0.069 13.6 0.1 0.11 12.9 0.1 1.4 1 0 0 1 1 1 0 Vinculin Binding Site RmlD_sub_bind PF04321.17 ABK73260.1 - 0.17 10.9 2.8 0.48 9.5 2.8 1.7 1 1 0 1 1 1 0 RmlD substrate binding domain Acyl-CoA_dh_2 PF08028.11 ABK73261.1 - 1.7e-11 44.5 6.9 3.6e-11 43.5 6.9 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK73261.1 - 1.5e-07 31.5 0.0 2.6e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 ABK73261.1 - 7.1e-07 29.6 1.5 1.4e-06 28.6 1.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK73261.1 - 0.00019 22.1 0.0 0.00039 21.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain TetR_N PF00440.23 ABK73262.1 - 7.5e-16 57.7 0.5 1.7e-15 56.5 0.1 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family GerE PF00196.19 ABK73263.1 - 1.3e-19 69.4 0.3 2.6e-19 68.5 0.0 1.6 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 ABK73263.1 - 2.6e-07 30.2 0.6 2.6e-07 30.2 0.6 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_24 PF13412.6 ABK73263.1 - 5.7e-06 25.8 0.2 1.1e-05 24.9 0.2 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 ABK73263.1 - 3.9e-05 23.1 0.5 0.0001 21.7 0.5 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 ABK73263.1 - 0.00016 21.4 0.5 0.00042 20.0 0.5 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 ABK73263.1 - 0.0012 18.5 0.2 0.0029 17.3 0.2 1.7 1 0 0 1 1 1 1 Homeodomain-like domain DUF742 PF05331.11 ABK73263.1 - 0.0044 16.8 1.8 0.0091 15.8 0.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF742) HTH_20 PF12840.7 ABK73263.1 - 0.0052 16.8 0.7 0.01 15.8 0.7 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 ABK73263.1 - 0.0067 16.4 0.1 0.016 15.2 0.1 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_11 PF08279.12 ABK73263.1 - 0.0084 16.0 0.2 0.016 15.1 0.2 1.5 1 0 0 1 1 1 1 HTH domain HTH_40 PF14493.6 ABK73263.1 - 0.011 16.2 0.0 0.022 15.2 0.0 1.6 2 0 0 2 2 1 0 Helix-turn-helix domain LexA_DNA_bind PF01726.16 ABK73263.1 - 0.024 14.4 0.1 0.1 12.4 0.1 2.0 1 1 0 1 1 1 0 LexA DNA binding domain MarR_2 PF12802.7 ABK73263.1 - 0.046 13.6 0.5 0.085 12.8 0.5 1.5 1 0 0 1 1 1 0 MarR family HTH_30 PF13556.6 ABK73263.1 - 0.049 13.4 0.3 0.1 12.4 0.3 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_5 PF01022.20 ABK73263.1 - 0.058 13.3 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_Tnp_ISL3 PF13542.6 ABK73263.1 - 0.07 12.6 2.3 0.59 9.6 0.2 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Peptidase_M3_N PF08439.10 ABK73263.1 - 0.1 12.8 0.1 3 8.2 0.1 2.3 1 1 1 2 2 2 0 Oligopeptidase F DUF881 PF05949.12 ABK73264.1 - 2.6e-34 118.2 0.1 4e-34 117.6 0.1 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF881) PNTB PF02233.16 ABK73265.1 - 2.7e-197 656.3 18.5 3.1e-197 656.1 18.5 1.0 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit FA_desaturase PF00487.24 ABK73265.1 - 6.3 6.5 15.7 0.54 10.0 4.3 2.4 1 1 1 2 2 2 0 Fatty acid desaturase Virul_fac_BrkB PF03631.15 ABK73266.1 - 9.2e-46 156.5 14.9 1.1e-45 156.4 14.9 1.0 1 0 0 1 1 1 1 Virulence factor BrkB DUF2070 PF09843.9 ABK73266.1 - 1.1 7.5 5.8 1.5 7.0 5.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Xan_ur_permease PF00860.20 ABK73267.1 - 3.7e-75 253.1 46.0 6e-75 252.4 46.0 1.3 1 1 0 1 1 1 1 Permease family G0-G1_switch_2 PF15103.6 ABK73267.1 - 4.6 7.7 4.6 1.6 9.2 0.2 2.4 2 0 0 2 2 2 0 G0/G1 switch protein 2 MFS_3 PF05977.13 ABK73268.1 - 1.4e-34 119.4 36.1 1.8e-34 119.1 36.1 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.16 ABK73268.1 - 4.6e-31 108.0 54.5 2.7e-17 62.7 21.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK73268.1 - 1e-06 27.9 9.9 1e-06 27.9 9.9 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 ABK73268.1 - 0.34 9.7 5.7 1.1 8.1 5.6 1.8 1 1 0 1 1 1 0 MFS_1 like family Pan_kinase PF03309.14 ABK73269.1 - 1.2e-56 191.8 0.2 1.5e-56 191.5 0.2 1.1 1 0 0 1 1 1 1 Type III pantothenate kinase Bac_luciferase PF00296.20 ABK73270.1 - 2.5e-52 178.2 8.5 3.5e-52 177.8 8.5 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase GTP_EFTU PF00009.27 ABK73271.1 - 1.2e-57 194.6 0.2 1.6e-57 194.2 0.2 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 ABK73271.1 - 2.5e-32 111.5 0.0 5.4e-32 110.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 ABK73271.1 - 3.7e-16 59.3 7.5 5.2e-16 58.8 6.3 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ABK73271.1 - 5.1e-06 26.6 0.5 1.8e-05 24.7 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase Bac_luciferase PF00296.20 ABK73272.1 - 5.2e-59 200.2 7.4 1.2e-58 199.1 7.4 1.4 1 1 0 1 1 1 1 Luciferase-like monooxygenase LAL_C2 PF18603.1 ABK73272.1 - 0.0054 16.9 0.1 0.036 14.2 0.1 2.4 2 0 0 2 2 2 1 L-amino acid ligase C-terminal domain 2 Robl_LC7 PF03259.17 ABK73273.1 - 1.3e-22 79.4 1.5 1.9e-22 78.8 1.1 1.5 2 0 0 2 2 2 1 Roadblock/LC7 domain Bac_luciferase PF00296.20 ABK73275.1 - 1e-39 136.8 7.3 1.4e-39 136.4 7.3 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Cutinase PF01083.22 ABK73276.1 - 9.4e-44 149.5 0.1 1.2e-43 149.2 0.1 1.0 1 0 0 1 1 1 1 Cutinase Abhydrolase_2 PF02230.16 ABK73276.1 - 0.01 15.7 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase VirJ PF06057.11 ABK73276.1 - 0.18 11.6 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Acetyltransf_1 PF00583.25 ABK73277.1 - 1.4e-17 64.0 0.0 1.7e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ABK73277.1 - 3e-12 46.6 0.0 3.9e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ABK73277.1 - 8.4e-09 35.3 0.0 1.3e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 ABK73277.1 - 4.9e-08 33.3 0.0 7.4e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ABK73277.1 - 7.9e-06 26.6 0.0 9.6e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ABK73277.1 - 0.0017 18.4 0.0 0.0028 17.7 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 ABK73277.1 - 0.0023 18.1 0.0 0.0027 17.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 ABK73277.1 - 0.0099 16.0 1.4 0.014 15.5 1.4 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Usp PF00582.26 ABK73278.1 - 6.4e-46 156.4 6.6 2.2e-23 83.3 0.4 2.4 2 1 0 2 2 2 2 Universal stress protein family PGM_PMM_I PF02878.16 ABK73278.1 - 0.0084 15.8 0.4 1.1 9.0 0.1 2.3 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I BPD_transp_1 PF00528.22 ABK73279.1 - 1.4e-13 51.0 20.4 4.5e-13 49.3 16.6 2.1 2 0 0 2 2 2 2 Binding-protein-dependent transport system inner membrane component Polyketide_cyc2 PF10604.9 ABK73280.1 - 4.8e-23 82.0 0.7 5.5e-23 81.8 0.7 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport BPD_transp_1 PF00528.22 ABK73281.1 - 1.7e-17 63.7 14.1 2.5e-17 63.2 13.4 1.5 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 ABK73281.1 - 0.0033 17.4 0.2 0.039 13.9 0.0 2.6 2 0 0 2 2 2 1 N-terminal TM domain of oligopeptide transport permease C Fic PF02661.18 ABK73282.1 - 2.5e-15 57.1 0.1 4.7e-15 56.3 0.1 1.4 1 0 0 1 1 1 1 Fic/DOC family VbhA PF18495.1 ABK73282.1 - 0.00011 22.0 0.1 0.0002 21.2 0.1 1.4 1 0 0 1 1 1 1 Antitoxin VbhA CoA_transf_3 PF02515.17 ABK73283.1 - 2.2e-18 66.5 3.2 7.6e-12 45.0 0.0 3.5 3 1 0 3 3 3 2 CoA-transferase family III TniB PF05621.11 ABK73283.1 - 5.8e-16 58.5 0.0 9.7e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein AAA_22 PF13401.6 ABK73283.1 - 3.8e-14 53.1 0.0 1e-13 51.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ABK73283.1 - 0.0024 18.3 0.1 0.015 15.7 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 ABK73283.1 - 0.017 14.9 0.0 0.072 12.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 ABK73283.1 - 0.026 14.5 0.1 0.15 12.1 0.1 2.1 1 1 0 1 1 1 0 AAA domain Glycos_transf_1 PF00534.20 ABK73284.1 - 2.5e-31 108.5 0.0 4.2e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ABK73284.1 - 1.2e-22 80.8 0.0 2.1e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ABK73284.1 - 3e-17 63.1 2.1 3e-17 63.1 2.1 1.9 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 ABK73284.1 - 6.4e-16 59.2 10.8 6.4e-16 59.2 10.8 2.5 3 0 0 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 ABK73284.1 - 7.7e-07 29.4 0.0 1.6e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pyr_redox_2 PF07992.14 ABK73285.1 - 1.7e-53 181.8 3.2 2e-53 181.5 3.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 ABK73285.1 - 1.1e-19 70.7 0.8 3e-19 69.4 0.1 2.1 2 0 0 2 2 2 1 Reductase C-terminal Pyr_redox PF00070.27 ABK73285.1 - 1.2e-15 57.8 10.0 3e-13 50.1 1.7 3.6 3 1 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ABK73285.1 - 3.7e-09 36.3 0.0 8.5e-09 35.1 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ABK73285.1 - 2.5e-07 30.8 8.3 0.079 13.2 1.2 3.6 3 0 0 3 3 3 3 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ABK73285.1 - 7.7e-07 28.2 1.8 0.009 14.8 0.0 3.3 2 1 1 3 3 3 2 HI0933-like protein DAO PF01266.24 ABK73285.1 - 7.6e-05 22.4 18.5 0.02 14.5 0.0 4.1 3 1 1 4 4 4 3 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 ABK73285.1 - 0.00042 19.7 2.3 0.00042 19.7 2.3 2.3 3 1 0 4 4 4 1 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 ABK73285.1 - 0.00092 18.6 0.7 0.67 9.2 0.3 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase 2-Hacid_dh_C PF02826.19 ABK73285.1 - 0.0035 16.7 0.1 0.021 14.2 0.1 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 ABK73285.1 - 0.014 14.5 2.0 3.5 6.6 0.0 2.5 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.18 ABK73285.1 - 0.035 14.0 1.1 0.069 13.0 1.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 ABK73285.1 - 0.14 12.2 10.6 4 7.4 0.5 4.3 3 1 1 4 4 4 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 ABK73285.1 - 0.26 11.7 1.6 7.6 7.0 0.8 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 ABK73285.1 - 0.29 10.2 15.8 0.34 9.9 0.1 4.0 4 1 0 4 4 4 0 FAD binding domain PqqA PF08042.11 ABK73285.1 - 0.54 10.4 1.7 0.72 10.0 0.4 2.0 2 0 0 2 2 2 0 PqqA family Carboxyl_trans PF01039.22 ABK73286.1 - 1.1e-136 456.4 0.0 1.3e-136 456.2 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 ABK73286.1 - 0.12 11.8 0.8 4 6.9 0.1 2.4 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) Aldedh PF00171.22 ABK73288.1 - 5.8e-140 466.9 0.0 6.9e-140 466.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family CofC PF01983.16 ABK73289.1 - 8.3e-15 54.5 0.0 1.2e-14 54.0 0.0 1.3 1 1 0 1 1 1 1 Guanylyl transferase CofC like NTP_transf_3 PF12804.7 ABK73289.1 - 3e-08 34.2 2.4 3.8e-08 33.8 2.4 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF2064 PF09837.9 ABK73289.1 - 0.015 15.2 0.4 0.045 13.6 0.1 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2064) HHH PF00633.23 ABK73289.1 - 0.12 12.3 0.9 0.25 11.3 0.1 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif NTP_transf_9 PF04248.12 ABK73290.1 - 7.3e-34 115.5 0.1 9.3e-34 115.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF427) BPD_transp_2 PF02653.16 ABK73292.1 - 6.3e-39 133.7 46.3 6.3e-39 133.7 46.3 1.3 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component ADH_zinc_N PF00107.26 ABK73293.1 - 2.9e-13 49.9 0.0 4.9e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ABK73293.1 - 5.8e-13 48.7 0.1 4.3e-12 45.9 0.0 2.4 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ABK73293.1 - 6.1e-05 24.1 0.0 0.00011 23.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ABK73293.1 - 7.5e-05 22.3 0.0 0.00023 20.7 0.0 1.7 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus TrkA_N PF02254.18 ABK73293.1 - 0.088 13.1 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.21 ABK73293.1 - 0.11 11.8 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ABK73293.1 - 0.13 11.6 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Response_reg PF00072.24 ABK73294.1 - 3.9e-19 68.9 0.6 7.2e-19 68.0 0.1 1.7 2 0 0 2 2 2 1 Response regulator receiver domain GerE PF00196.19 ABK73294.1 - 4.8e-14 51.6 0.0 8.9e-14 50.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 ABK73294.1 - 1.5e-06 27.8 0.1 2.9e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 ABK73294.1 - 0.0016 17.9 0.2 0.0074 15.8 0.1 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_38 PF13936.6 ABK73294.1 - 0.0071 16.1 0.2 0.014 15.1 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain KORA PF16509.5 ABK73294.1 - 0.087 13.1 0.1 0.26 11.6 0.0 1.8 2 0 0 2 2 2 0 TrfB plasmid transcriptional repressor T2SSF PF00482.23 ABK73294.1 - 0.11 12.5 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F HTH_28 PF13518.6 ABK73294.1 - 0.13 12.4 2.2 0.46 10.6 0.3 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain FhuF_C PF11575.8 ABK73295.1 - 1.6e-09 37.5 5.6 1.6e-09 37.5 5.6 1.7 2 0 0 2 2 2 1 FhuF 2Fe-2S C-terminal domain FhuF PF06276.12 ABK73295.1 - 0.066 13.6 0.0 0.13 12.7 0.0 1.5 1 1 0 1 1 1 0 Ferric iron reductase FhuF-like transporter Mycobact_memb PF05423.13 ABK73296.1 - 3.1e-62 208.6 0.0 3.5e-62 208.4 0.0 1.0 1 0 0 1 1 1 1 Mycobacterium membrane protein Wzy_C_2 PF11846.8 ABK73297.1 - 0.14 12.0 2.2 0.2 11.5 0.5 2.0 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal PhoR PF11808.8 ABK73297.1 - 0.15 12.5 4.5 0.077 13.4 1.3 2.0 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR CDC45 PF02724.14 ABK73297.1 - 0.44 8.8 3.6 0.55 8.5 3.6 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4381 PF14316.6 ABK73297.1 - 1.3 9.3 7.1 2.6 8.3 2.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) TFIIF_alpha PF05793.12 ABK73297.1 - 1.7 7.1 11.8 2.5 6.6 11.8 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.12 ABK73297.1 - 6.5 6.1 15.5 10 5.5 15.5 1.2 1 0 0 1 1 1 0 SDA1 adh_short PF00106.25 ABK73298.1 - 7.7e-50 169.1 1.1 9.8e-50 168.7 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK73298.1 - 1.2e-34 119.9 1.7 1.6e-34 119.5 1.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK73298.1 - 2.4e-12 47.1 0.2 4.3e-12 46.3 0.2 1.3 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 ABK73298.1 - 0.008 15.5 0.9 0.016 14.5 0.1 2.0 2 1 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AdoHcyase_NAD PF00670.21 ABK73298.1 - 0.55 10.3 3.0 0.94 9.5 0.8 2.2 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Polysacc_deac_1 PF01522.21 ABK73299.1 - 7.4e-28 96.9 0.0 1.8e-27 95.7 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase 7TM_GPCR_Srz PF10325.9 ABK73300.1 - 0.072 12.4 0.0 0.084 12.2 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srz DUF2127 PF09900.9 ABK73300.1 - 2.7 8.2 17.2 0.1 12.8 8.2 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2127) Peptidase_M78 PF06114.13 ABK73301.1 - 0.0019 18.1 0.0 0.023 14.6 0.0 2.0 1 1 1 2 2 2 2 IrrE N-terminal-like domain MFS_1 PF07690.16 ABK73302.1 - 1e-44 152.9 66.1 9.7e-43 146.4 62.1 3.2 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ABK73302.1 - 1.2e-18 66.9 25.6 2.1e-18 66.1 25.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ABK73302.1 - 3.2e-12 46.1 16.1 3.2e-12 46.1 16.1 3.3 1 1 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 ABK73302.1 - 0.67 8.2 18.3 0.25 9.6 5.2 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family adh_short_C2 PF13561.6 ABK73303.1 - 3.6e-57 193.6 0.6 4.3e-57 193.4 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK73303.1 - 5.4e-52 176.1 0.1 6.3e-52 175.9 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK73303.1 - 6.3e-16 58.8 0.4 8.5e-16 58.4 0.4 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 ABK73303.1 - 0.018 14.9 0.2 0.029 14.3 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PALP PF00291.25 ABK73303.1 - 0.22 10.9 3.9 0.4 10.1 3.8 1.5 1 1 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Glyco_trans_4_4 PF13579.6 ABK73303.1 - 0.34 11.3 14.5 2.1 8.8 0.9 3.0 2 1 0 3 3 3 0 Glycosyl transferase 4-like domain Methyltransf_25 PF13649.6 ABK73304.1 - 3.5e-17 62.9 0.1 5.9e-17 62.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABK73304.1 - 6e-16 58.9 0.0 9.4e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ABK73304.1 - 6.3e-12 45.3 0.0 9.4e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 ABK73304.1 - 1.7e-07 31.2 0.0 2.3e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK73304.1 - 2.9e-05 24.7 0.0 4.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABK73304.1 - 0.00011 22.1 0.0 0.00016 21.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 ABK73304.1 - 0.0009 18.9 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW UPF0020 PF01170.18 ABK73304.1 - 0.002 17.8 0.7 0.031 14.0 0.7 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Met_10 PF02475.16 ABK73304.1 - 0.02 14.6 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein TehB PF03848.14 ABK73304.1 - 0.049 13.0 0.0 0.07 12.5 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB PrmA PF06325.13 ABK73304.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.15 ABK73304.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase ADH_zinc_N PF00107.26 ABK73305.1 - 9e-27 93.6 0.1 1.6e-26 92.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ABK73305.1 - 1.1e-19 71.8 0.0 2.2e-19 70.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ABK73305.1 - 1.4e-06 28.1 0.0 4.1e-05 23.4 0.0 2.2 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain DapB_N PF01113.20 ABK73305.1 - 0.012 15.7 0.7 0.022 14.9 0.7 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PA PF02225.22 ABK73305.1 - 0.03 14.3 1.6 0.12 12.4 0.7 2.4 2 1 0 2 2 2 0 PA domain Radical_SAM PF04055.21 ABK73306.1 - 1e-29 104.1 0.0 2.2e-29 103.0 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily UPF0004 PF00919.20 ABK73306.1 - 1.5e-28 98.7 0.0 3e-28 97.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 B12-binding PF02310.19 ABK73306.1 - 0.00096 19.2 0.0 0.0023 18.0 0.0 1.6 1 0 0 1 1 1 1 B12 binding domain AHD PF17793.1 ABK73306.1 - 0.24 11.2 0.1 0.44 10.4 0.1 1.4 1 0 0 1 1 1 0 ANC1 homology domain (AHD) Lyase_1 PF00206.20 ABK73307.1 - 1.9e-61 208.2 0.0 4.5e-61 207.0 0.0 1.6 2 0 0 2 2 2 1 Lyase ASL_C2 PF14698.6 ABK73307.1 - 1.1e-21 77.3 0.0 3.7e-21 75.7 0.0 2.0 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Molybdopterin PF00384.22 ABK73308.1 - 7e-60 203.2 0.0 5.6e-59 200.2 0.0 1.9 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 ABK73308.1 - 1e-20 73.8 0.0 2.8e-20 72.4 0.0 1.7 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 ABK73308.1 - 1.2e-12 47.6 0.5 2.9e-12 46.4 0.5 1.7 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain PUA_3 PF17785.1 ABK73308.1 - 0.057 13.2 0.0 0.36 10.7 0.0 2.2 2 0 0 2 2 2 0 PUA-like domain ADD_DNMT3 PF17980.1 ABK73308.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Cysteine rich ADD domain in DNMT3 MbtH PF03621.13 ABK73309.1 - 6.6e-30 102.3 0.1 8.2e-30 102.0 0.1 1.1 1 0 0 1 1 1 1 MbtH-like protein T2SSF PF00482.23 ABK73310.1 - 3.7e-11 43.1 1.2 5.1e-11 42.6 1.2 1.2 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F MlaD PF02470.20 ABK73311.1 - 2.9e-11 43.5 0.1 5.6e-11 42.6 0.1 1.5 1 0 0 1 1 1 1 MlaD protein Cupin_5 PF06172.11 ABK73312.1 - 2.9e-47 160.4 0.0 3.4e-47 160.1 0.0 1.0 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Methyltransf_9 PF08003.11 ABK73312.1 - 0.05 12.5 0.0 0.067 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) ABC_tran PF00005.27 ABK73313.1 - 2.6e-31 109.0 0.0 4.3e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter OB_MalK PF17912.1 ABK73313.1 - 5.6e-09 36.7 0.1 2.3e-08 34.7 0.1 2.2 1 0 0 1 1 1 1 MalK OB fold domain TOBE_2 PF08402.10 ABK73313.1 - 4.9e-07 29.8 3.9 8.7e-07 29.0 0.4 2.9 4 0 0 4 4 4 1 TOBE domain AAA_21 PF13304.6 ABK73313.1 - 3.4e-06 27.1 0.0 0.0012 18.7 0.0 2.4 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system TOBE PF03459.17 ABK73313.1 - 0.00046 20.4 0.5 0.0012 19.0 0.2 1.9 2 0 0 2 2 1 1 TOBE domain RsgA_GTPase PF03193.16 ABK73313.1 - 0.00051 20.0 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 ABK73313.1 - 0.0013 19.0 0.0 0.0025 18.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ABK73313.1 - 0.0035 17.0 0.0 0.0072 16.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 ABK73313.1 - 0.0041 16.9 0.2 0.008 15.9 0.2 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ABK73313.1 - 0.0061 17.0 0.3 0.011 16.1 0.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 ABK73313.1 - 0.0088 15.5 0.0 2.5 7.5 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 ABK73313.1 - 0.016 15.4 0.0 0.041 14.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 ABK73313.1 - 0.027 14.4 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain CysA_C_terminal PF17850.1 ABK73313.1 - 0.042 14.4 0.1 0.24 12.0 0.0 2.4 2 0 0 2 2 2 0 CysA C-terminal regulatory domain AAA_25 PF13481.6 ABK73313.1 - 0.046 13.3 0.1 0.18 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 ABK73313.1 - 0.062 13.8 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ABK73313.1 - 0.1 12.8 0.0 0.29 11.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_23 PF13476.6 ABK73313.1 - 0.11 12.9 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 ABK73313.1 - 0.12 12.0 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Ribosomal_S17 PF00366.20 ABK73313.1 - 0.16 12.1 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S17 AAA_24 PF13479.6 ABK73313.1 - 0.16 11.6 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Condensation PF00668.20 ABK73314.1 - 6.3e-13 48.2 0.0 7.3e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 Condensation domain CDP-OH_P_transf PF01066.21 ABK73315.1 - 3.5e-12 46.9 1.5 3.5e-12 46.9 1.5 2.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PRA1 PF03208.19 ABK73315.1 - 6.8 6.3 13.9 5.4 6.6 3.8 2.5 1 1 1 2 2 2 0 PRA1 family protein ATP-synt_B PF00430.18 ABK73316.1 - 1.1e-28 100.0 8.5 1.3e-28 99.7 8.5 1.1 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) Phage_holin_6_1 PF09682.10 ABK73316.1 - 0.00046 20.6 1.7 0.028 14.8 1.1 2.2 1 1 1 2 2 2 1 Bacteriophage holin of superfamily 6 (Holin_LLH) Apolipoprotein PF01442.18 ABK73316.1 - 0.022 14.6 14.5 0.042 13.7 14.5 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1640 PF07798.11 ABK73316.1 - 0.084 12.9 1.6 0.13 12.3 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF3853 PF12964.7 ABK73316.1 - 0.095 12.9 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3853) Fzo_mitofusin PF04799.13 ABK73316.1 - 0.17 11.4 3.0 0.31 10.6 0.1 2.1 1 1 1 2 2 2 0 fzo-like conserved region TMPIT PF07851.13 ABK73316.1 - 0.25 10.6 0.9 0.3 10.3 0.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein TPR_MLP1_2 PF07926.12 ABK73316.1 - 0.35 10.9 14.9 1.2 9.2 14.9 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein V-ATPase_G_2 PF16999.5 ABK73316.1 - 0.63 10.5 21.4 1.4 9.3 21.4 1.6 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit HisKA_3 PF07730.13 ABK73316.1 - 3.1 8.4 10.5 4.2 8.0 3.7 2.3 1 1 1 2 2 2 0 Histidine kinase DUF883 PF05957.13 ABK73316.1 - 3.4 8.3 14.6 17 6.1 12.2 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) ABC_tran PF00005.27 ABK73317.1 - 3.2e-32 111.9 0.0 4.5e-32 111.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 ABK73317.1 - 2.6e-18 66.3 0.1 5.7e-18 65.2 0.1 1.6 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 ABK73317.1 - 1.2e-06 28.5 0.1 0.00052 19.9 0.1 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ABK73317.1 - 8.2e-05 22.9 0.4 0.0014 18.9 0.4 2.2 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 ABK73317.1 - 0.0002 20.9 0.0 0.00066 19.2 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ABK73317.1 - 0.0003 21.2 0.1 0.00055 20.4 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 ABK73317.1 - 0.0017 18.8 0.0 0.068 13.6 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 ABK73317.1 - 0.0029 17.0 0.0 0.56 9.6 0.0 2.2 2 0 0 2 2 2 1 Bacterial TniB protein RsgA_GTPase PF03193.16 ABK73317.1 - 0.0066 16.4 0.0 0.023 14.6 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase NACHT PF05729.12 ABK73317.1 - 0.0097 15.8 0.0 0.027 14.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_13 PF13166.6 ABK73317.1 - 0.013 14.2 0.1 0.1 11.2 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 ABK73317.1 - 0.016 15.2 0.2 0.28 11.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 ABK73317.1 - 0.019 14.7 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ABK73317.1 - 0.038 14.1 0.0 0.19 11.8 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 ABK73317.1 - 0.044 13.9 0.0 0.08 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 ABK73317.1 - 0.051 12.5 0.0 0.076 12.0 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 ABK73317.1 - 0.09 12.3 0.0 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ABK73317.1 - 0.09 13.2 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 ABK73317.1 - 0.093 12.4 0.1 1.8 8.3 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.22 ABK73317.1 - 0.17 11.1 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_7 PF12775.7 ABK73317.1 - 0.19 11.2 0.0 0.37 10.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 ABK73317.1 - 0.22 11.2 0.0 0.43 10.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF3021 PF11457.8 ABK73319.1 - 0.0089 16.4 0.6 0.011 16.0 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3021) DUF5325 PF17259.2 ABK73319.1 - 4.2 7.3 10.2 0.062 13.2 2.3 2.0 3 0 0 3 3 3 0 Family of unknown function (DUF5325) Citrate_synt PF00285.21 ABK73320.1 - 1.6e-25 89.9 0.2 1.6e-24 86.7 0.2 1.3 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain BacA PF02673.18 ABK73321.1 - 3.2e-83 279.4 13.5 3.8e-83 279.1 13.5 1.0 1 0 0 1 1 1 1 Bacitracin resistance protein BacA DNA_processg_A PF02481.15 ABK73321.1 - 0.025 13.9 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 DNA recombination-mediator protein A Trehalose_PPase PF02358.16 ABK73322.1 - 1.9e-31 109.0 0.0 2.4e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Trehalose-phosphatase Glyoxalase PF00903.25 ABK73322.1 - 0.0084 16.3 0.1 0.075 13.2 0.0 2.3 1 1 1 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Abhydrolase_1 PF00561.20 ABK73323.1 - 1.8e-18 67.1 0.4 1.9e-12 47.4 0.7 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK73323.1 - 3.1e-15 57.4 17.6 3.8e-15 57.1 17.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK73323.1 - 1.4e-06 27.8 1.1 1.2e-05 24.7 1.1 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 His_kinase PF06580.13 ABK73324.1 - 2.9e-23 82.0 0.0 5.1e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase HATPase_c PF02518.26 ABK73324.1 - 3.6e-09 37.1 0.0 6.9e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 ABK73324.1 - 3.8e-06 26.9 0.1 1e-05 25.5 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 ABK73324.1 - 0.0011 18.8 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PUA PF01472.20 ABK73325.1 - 0.46 10.5 3.2 1.9 8.5 0.8 2.6 2 1 0 2 2 2 0 PUA domain TadE PF07811.12 ABK73325.1 - 0.64 10.3 6.4 7.4 6.9 1.2 2.6 2 0 0 2 2 2 0 TadE-like protein LCM PF04072.14 ABK73326.1 - 7.7e-66 221.6 0.6 1.1e-65 221.1 0.6 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Phage_r1t_holin PF16945.5 ABK73326.1 - 1.9 8.8 7.6 0.22 11.7 1.5 2.5 2 1 1 3 3 3 0 Putative lactococcus lactis phage r1t holin MR_MLE_C PF13378.6 ABK73327.1 - 6.6e-52 176.3 0.3 9e-52 175.8 0.3 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 ABK73327.1 - 7.8e-15 55.1 0.0 1.3e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain AAA_12 PF13087.6 ABK73328.1 - 1.4e-26 93.4 0.0 2.2e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain RNase_H_2 PF13482.6 ABK73328.1 - 1.6e-15 57.5 0.0 2.4e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 RNase_H superfamily AAA_30 PF13604.6 ABK73328.1 - 2.5e-12 46.9 0.0 7.6e-12 45.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ABK73328.1 - 1.2e-08 35.1 0.1 0.0013 18.5 0.0 2.5 3 0 0 3 3 3 2 AAA domain UvrD_C_2 PF13538.6 ABK73328.1 - 5.9e-06 26.0 0.4 1.5e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 ABK73328.1 - 1e-05 25.9 0.0 0.00011 22.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 ABK73328.1 - 0.00086 19.3 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 ABK73328.1 - 0.0021 18.5 0.2 0.037 14.4 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain Viral_helicase1 PF01443.18 ABK73328.1 - 0.0031 17.3 0.1 1.5 8.5 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 ABK73328.1 - 0.0049 16.8 0.0 0.0091 15.9 0.0 1.4 1 0 0 1 1 1 1 Helicase AAA PF00004.29 ABK73328.1 - 0.017 15.5 0.0 0.046 14.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ABK73328.1 - 0.02 15.2 0.0 0.05 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2779 PF11074.8 ABK73328.1 - 0.21 12.0 0.0 0.43 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function(DUF2779) HTH_1 PF00126.27 ABK73329.1 - 3.9e-18 65.1 0.1 9e-18 64.0 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 ABK73329.1 - 4.1e-17 62.2 1.4 5.6e-17 61.8 0.4 1.7 1 1 1 2 2 2 1 LysR substrate binding domain MarR_2 PF12802.7 ABK73329.1 - 0.02 14.8 0.1 0.055 13.4 0.1 1.7 1 0 0 1 1 1 0 MarR family HTH_5 PF01022.20 ABK73329.1 - 0.068 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Bac_luciferase PF00296.20 ABK73330.1 - 7e-43 147.2 5.5 7e-43 147.2 5.5 1.5 2 0 0 2 2 2 1 Luciferase-like monooxygenase ABC_tran PF00005.27 ABK73331.1 - 1.6e-33 116.1 0.0 2.1e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK73331.1 - 1.7e-06 28.0 0.1 0.006 16.4 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ABK73331.1 - 0.0016 18.1 0.0 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 ABK73331.1 - 0.0029 18.0 0.9 0.005 17.2 0.9 1.7 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 ABK73331.1 - 0.0043 17.0 0.1 0.0085 16.0 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase SbcCD_C PF13558.6 ABK73331.1 - 0.012 15.9 0.1 0.2 11.9 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 ABK73331.1 - 0.016 14.6 0.0 1.3 8.5 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ABK73331.1 - 0.031 14.6 0.1 0.071 13.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ABK73331.1 - 0.056 13.6 0.3 0.068 13.3 0.3 1.4 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ABK73331.1 - 0.08 13.4 0.0 0.12 12.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 ABK73331.1 - 0.18 10.9 0.0 0.26 10.4 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit Peripla_BP_3 PF13377.6 ABK73332.1 - 7e-18 65.5 1.0 1.1e-16 61.6 0.6 2.5 2 1 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 ABK73332.1 - 4.1e-14 52.7 0.0 2.1e-07 30.6 0.0 2.0 2 0 0 2 2 2 2 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 ABK73332.1 - 3e-07 30.3 0.0 7.3e-07 29.0 0.0 1.5 1 1 0 1 1 1 1 Periplasmic binding protein domain LacI PF00356.21 ABK73332.1 - 1.6e-05 24.6 0.0 4.2e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family HTH_10 PF04967.12 ABK73332.1 - 0.013 15.3 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 HTH DNA binding domain GntR PF00392.21 ABK73332.1 - 0.023 14.4 0.4 0.13 12.0 0.1 2.5 3 1 0 3 3 3 0 Bacterial regulatory proteins, gntR family HTH_11 PF08279.12 ABK73332.1 - 0.087 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 HTH domain MarR_2 PF12802.7 ABK73332.1 - 0.1 12.5 0.1 0.53 10.2 0.1 2.3 2 0 0 2 2 2 0 MarR family HTH_38 PF13936.6 ABK73332.1 - 0.23 11.2 0.5 1.6 8.6 0.1 2.4 1 1 1 2 2 2 0 Helix-turn-helix domain Nramp PF01566.18 ABK73333.1 - 4.4e-55 187.1 27.7 6.7e-55 186.5 27.7 1.3 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Acyl-CoA_dh_1 PF00441.24 ABK73334.1 - 3.4e-13 50.0 6.4 6.1e-13 49.2 6.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK73334.1 - 0.00012 22.7 0.4 0.00039 21.1 0.0 2.0 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain PRTase_2 PF15609.6 ABK73334.1 - 0.057 12.9 0.8 0.28 10.7 0.0 2.1 2 0 0 2 2 2 0 Phosphoribosyl transferase Peripla_BP_3 PF13377.6 ABK73336.1 - 2.5e-29 102.7 0.7 6.2e-29 101.5 0.2 1.8 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 ABK73336.1 - 2e-17 63.5 0.0 3.5e-17 62.7 0.0 1.3 1 1 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 ABK73336.1 - 7.9e-15 54.4 0.1 1.7e-14 53.4 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 ABK73336.1 - 2.5e-14 53.5 0.0 2.1e-08 34.1 0.0 2.2 2 0 0 2 2 2 2 Periplasmic binding protein domain HTH_31 PF13560.6 ABK73336.1 - 0.00025 21.3 4.9 0.00041 20.6 2.3 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 ABK73336.1 - 0.0063 16.6 0.0 0.019 15.0 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 ABK73336.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain TetR_N PF00440.23 ABK73336.1 - 0.16 11.8 0.4 0.16 11.8 0.4 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family YceG PF02618.16 ABK73337.1 - 7e-67 225.9 0.0 8.4e-67 225.6 0.0 1.0 1 0 0 1 1 1 1 YceG-like family Dioxygenase_C PF00775.21 ABK73337.1 - 0.048 13.1 0.0 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 Dioxygenase PE-PPE PF08237.11 ABK73338.1 - 8.8e-71 238.1 0.1 1.6e-70 237.2 0.1 1.4 1 0 0 1 1 1 1 PE-PPE domain DUF445 PF04286.12 ABK73339.1 - 8.8e-108 361.4 0.1 1e-107 361.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF445) DUF3040 PF11239.8 ABK73339.1 - 0.029 14.6 2.3 0.074 13.3 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) LapA_dom PF06305.11 ABK73339.1 - 7.7 6.4 5.6 1 9.2 1.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain FAD_binding_3 PF01494.19 ABK73340.1 - 1.7e-18 67.0 1.1 6.5e-18 65.1 0.1 2.2 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 ABK73340.1 - 0.00011 21.6 0.1 0.058 12.6 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ABK73340.1 - 0.00022 21.0 1.5 0.24 10.9 0.9 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ABK73340.1 - 0.0041 17.3 0.5 0.011 15.9 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ABK73340.1 - 0.017 15.6 0.1 0.052 14.1 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ABK73340.1 - 0.048 12.7 0.2 0.073 12.1 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 ABK73340.1 - 0.054 12.5 0.2 0.18 10.8 0.2 1.8 1 1 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.7 ABK73340.1 - 0.16 11.3 1.5 0.23 10.8 1.5 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FCD PF07729.12 ABK73341.1 - 7.1e-20 71.7 7.3 1.4e-19 70.7 7.3 1.5 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 ABK73341.1 - 1.4e-17 63.1 4.7 1.5e-17 62.9 0.2 2.8 2 1 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 ABK73341.1 - 7.1e-06 25.9 0.0 1.5e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Rrf2 PF02082.20 ABK73341.1 - 0.00011 22.5 0.2 0.00079 19.7 0.0 2.4 1 1 1 2 2 2 1 Transcriptional regulator MarR_2 PF12802.7 ABK73341.1 - 0.0003 20.6 1.1 0.0011 18.8 0.1 2.4 2 1 0 2 2 2 1 MarR family TrmB PF01978.19 ABK73341.1 - 0.0012 18.7 0.0 0.0059 16.5 0.0 2.0 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Fe_dep_repress PF01325.19 ABK73341.1 - 0.004 17.3 0.0 0.0089 16.2 0.0 1.6 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_24 PF13412.6 ABK73341.1 - 0.062 12.9 0.1 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 ABK73341.1 - 0.063 13.1 1.4 0.11 12.4 0.2 2.1 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_36 PF13730.6 ABK73341.1 - 0.16 11.9 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Abhydrolase_6 PF12697.7 ABK73343.1 - 9.4e-15 55.8 8.3 1.1e-14 55.6 8.3 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ABK73343.1 - 1.8e-07 31.1 0.0 2.6e-05 24.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ABK73343.1 - 0.00015 21.2 0.0 0.00023 20.5 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 ArsA_ATPase PF02374.15 ABK73345.1 - 6.4e-43 147.1 0.0 1e-42 146.4 0.0 1.3 1 0 0 1 1 1 1 Anion-transporting ATPase ArsA_HSP20 PF17886.1 ABK73345.1 - 3.1e-12 45.9 0.1 7.5e-12 44.6 0.1 1.7 1 0 0 1 1 1 1 HSP20-like domain found in ArsA AAA_31 PF13614.6 ABK73345.1 - 3e-06 27.3 0.0 8.1e-06 25.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 ABK73345.1 - 4.2e-05 23.6 0.0 6.4e-05 23.0 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 ABK73345.1 - 5.1e-05 22.8 0.3 0.00014 21.4 0.1 1.7 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 ABK73345.1 - 0.00072 19.1 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MeaB PF03308.16 ABK73345.1 - 0.0086 15.1 1.3 0.013 14.5 0.5 1.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 ABK73345.1 - 0.01 15.4 0.3 0.029 14.0 0.2 1.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 ABK73345.1 - 0.011 15.5 0.1 0.023 14.4 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 ABK73345.1 - 0.012 15.5 0.1 0.02 14.8 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase SRP54 PF00448.22 ABK73345.1 - 0.029 14.0 0.3 0.058 13.0 0.3 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PhoH PF02562.16 ABK73345.1 - 0.04 13.4 0.1 0.07 12.6 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.6 ABK73345.1 - 0.069 13.5 0.7 0.22 11.9 0.6 1.8 1 1 0 1 1 1 0 AAA ATPase domain CobA_CobO_BtuR PF02572.15 ABK73345.1 - 0.1 12.8 0.1 0.49 10.6 0.1 2.0 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP ATPase PF06745.13 ABK73345.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_30 PF13604.6 ABK73345.1 - 0.11 12.2 2.0 0.38 10.4 2.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ABK73345.1 - 0.14 12.3 0.2 0.34 11.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_29 PF13555.6 ABK73345.1 - 0.16 11.8 0.1 0.47 10.2 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain An_peroxidase PF03098.15 ABK73346.1 - 1.5e-113 380.2 0.0 1.9e-113 379.9 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase NTP_transf_3 PF12804.7 ABK73347.1 - 1.6e-28 100.1 6.7 1.9e-28 99.8 6.7 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain Ldh_1_N PF00056.23 ABK73347.1 - 0.028 14.5 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain IspD PF01128.19 ABK73347.1 - 0.15 11.8 1.7 0.31 10.7 0.5 1.9 1 1 1 2 2 2 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase BPD_transp_1 PF00528.22 ABK73348.1 - 1.8e-12 47.4 13.9 1.8e-12 47.4 13.9 2.4 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF5130 PF17174.4 ABK73349.1 - 1.1e-65 219.9 0.5 1.4e-65 219.6 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5130) TPM_phosphatase PF04536.14 ABK73349.1 - 0.062 13.5 0.0 0.086 13.0 0.0 1.2 1 0 0 1 1 1 0 TPM domain Condensation PF00668.20 ABK73350.1 - 3.7e-15 55.6 0.0 6.3e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 Condensation domain Phytase-like PF13449.6 ABK73352.1 - 6.3e-80 269.2 0.0 7.3e-80 269.0 0.0 1.0 1 0 0 1 1 1 1 Esterase-like activity of phytase TED PF08341.11 ABK73354.1 - 5.7e-10 39.5 0.0 2.4e-08 34.3 0.0 2.1 2 0 0 2 2 2 1 Thioester domain FR47 PF08445.10 ABK73354.1 - 0.011 15.7 0.1 4.2 7.4 0.0 2.3 2 0 0 2 2 2 0 FR47-like protein HCBP_related PF06594.11 ABK73354.1 - 0.15 12.1 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Haemolysin-type calcium binding protein related domain ketoacyl-synt PF00109.26 ABK73355.1 - 1.6e-51 175.4 4.2 9.9e-50 169.5 1.0 2.1 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 ABK73355.1 - 2e-31 108.5 1.4 3.6e-31 107.6 1.4 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 ABK73355.1 - 9.6e-08 31.7 2.9 2.6e-06 27.0 0.6 2.2 2 0 0 2 2 2 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 ABK73355.1 - 0.02 14.5 0.4 0.02 14.5 0.4 2.0 2 0 0 2 2 2 0 Thiolase, C-terminal domain FA_hydroxylase PF04116.13 ABK73356.1 - 2.7e-27 95.7 13.0 5.7e-27 94.7 13.0 1.5 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily SIS PF01380.22 ABK73357.1 - 1.4e-31 109.0 0.2 2.2e-14 53.5 0.3 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 ABK73357.1 - 4.5e-20 72.2 0.3 9.2e-20 71.2 0.3 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 ABK73357.1 - 4.9e-16 58.8 0.0 8.1e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 ABK73357.1 - 0.0039 16.1 0.3 0.0076 15.2 0.3 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II adh_short_C2 PF13561.6 ABK73358.1 - 4.2e-62 209.8 6.5 5e-62 209.5 6.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK73358.1 - 2.6e-54 183.7 2.2 3.2e-54 183.4 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK73358.1 - 1.3e-15 57.8 3.4 1.8e-15 57.4 3.4 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 ABK73358.1 - 0.0033 17.3 2.5 0.0049 16.8 2.5 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 ABK73358.1 - 0.025 14.0 0.4 0.032 13.7 0.4 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family CbiA PF01656.23 ABK73358.1 - 0.039 14.0 0.0 0.072 13.2 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain 3Beta_HSD PF01073.19 ABK73358.1 - 0.073 12.1 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_25 PF13649.6 ABK73358.1 - 0.073 13.8 0.2 0.12 13.0 0.2 1.5 1 0 0 1 1 1 0 Methyltransferase domain AAA_31 PF13614.6 ABK73358.1 - 0.3 11.0 0.4 0.51 10.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain Glycolytic PF00274.19 ABK73360.1 - 3.7e-10 39.1 0.0 4.2e-09 35.6 0.0 2.0 1 1 1 2 2 2 2 Fructose-bisphosphate aldolase class-I MR_MLE_C PF13378.6 ABK73361.1 - 8.7e-65 218.4 0.2 1.1e-64 218.0 0.2 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 ABK73361.1 - 5e-26 91.2 0.0 1.1e-25 90.1 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Carboxyl_trans PF01039.22 ABK73362.1 - 4.8e-83 279.5 0.6 5.9e-83 279.2 0.6 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain ECH_1 PF00378.20 ABK73362.1 - 0.00038 19.9 0.7 0.00095 18.5 0.7 1.6 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase SBP_bac_5 PF00496.22 ABK73363.1 - 6.2e-36 124.2 0.2 9.4e-36 123.6 0.2 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle CDP-OH_P_transf PF01066.21 ABK73364.1 - 4.3e-10 40.2 1.9 4.3e-10 40.2 1.9 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Nitroreductase PF00881.24 ABK73366.1 - 1.6e-12 47.8 7.4 2e-06 28.0 1.6 3.9 2 2 1 3 3 3 3 Nitroreductase family TM1586_NiRdase PF14512.6 ABK73366.1 - 0.00072 19.2 0.0 0.024 14.2 0.0 2.3 2 0 0 2 2 2 1 Putative TM nitroreductase TatC PF00902.18 ABK73367.1 - 2.2e-60 204.1 10.2 2.7e-60 203.7 10.2 1.1 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) DUF2070 PF09843.9 ABK73367.1 - 1.1 7.4 10.7 1.5 7.0 10.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PIG-Y PF15159.6 ABK73367.1 - 1.6 9.7 6.6 0.41 11.6 1.9 2.4 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y F420H2_quin_red PF04075.14 ABK73368.1 - 5.3e-28 97.7 0.2 1e-27 96.8 0.1 1.5 1 1 1 2 2 2 1 F420H(2)-dependent quinone reductase LPD38 PF18857.1 ABK73368.1 - 0.087 13.0 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Large polyvalent protein associated domain 38 Putative_PNPOx PF01243.20 ABK73368.1 - 0.17 12.1 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase MFS_1 PF07690.16 ABK73369.1 - 5.7e-24 84.7 66.1 1.5e-15 57.0 35.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK73369.1 - 1.1e-13 50.9 29.6 6.5e-12 45.0 12.5 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter Holin_SPP1 PF04688.13 ABK73369.1 - 0.32 11.2 3.0 13 6.0 0.3 2.7 2 0 0 2 2 2 0 SPP1 phage holin MaoC_dehydratas PF01575.19 ABK73370.1 - 4.2e-20 71.5 0.7 5.4e-20 71.2 0.7 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 ABK73370.1 - 5.7e-05 23.3 0.0 7.3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase Dyp_perox PF04261.12 ABK73371.1 - 3.4e-103 345.1 0.0 3.9e-103 344.9 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family TetR_N PF00440.23 ABK73372.1 - 1.1e-13 50.7 0.1 2.4e-13 49.6 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_Tnp_1_2 PF13022.6 ABK73372.1 - 0.00032 20.8 0.0 0.00058 20.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of insertion element transposase LacI PF00356.21 ABK73372.1 - 0.049 13.4 0.5 0.3 10.9 0.0 2.4 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family HTH_24 PF13412.6 ABK73372.1 - 0.05 13.2 0.0 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Sigma54_CBD PF04963.13 ABK73372.1 - 0.094 12.6 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain TetR_C_15 PF17918.1 ABK73372.1 - 0.11 13.3 5.5 0.26 12.0 1.9 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HTH_40 PF14493.6 ABK73372.1 - 0.13 12.8 0.0 0.32 11.5 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain FmdA_AmdA PF03069.15 ABK73373.1 - 1.9e-28 99.4 0.1 3.3e-19 69.0 0.0 2.7 1 1 1 2 2 2 2 Acetamidase/Formamidase family SIP PF04954.13 ABK73374.1 - 1.3e-34 119.2 0.3 2e-34 118.6 0.3 1.3 1 0 0 1 1 1 1 Siderophore-interacting protein FAD_binding_9 PF08021.11 ABK73374.1 - 5.4e-33 113.8 0.1 3.3e-32 111.3 0.0 2.3 3 0 0 3 3 3 1 Siderophore-interacting FAD-binding domain PMT_2 PF13231.6 ABK73375.1 - 3.1e-17 63.2 12.9 3.1e-17 63.2 12.9 2.2 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase CheC PF04509.12 ABK73375.1 - 4.1 7.4 5.9 2.6 8.0 0.1 2.9 3 0 0 3 3 3 0 CheC-like family FUSC_2 PF13515.6 ABK73376.1 - 6e-14 52.3 18.9 6e-14 52.3 18.9 2.9 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 ABK73376.1 - 1.1e-06 27.6 19.4 1.1e-06 27.6 19.4 2.4 2 0 0 2 2 2 2 Fusaric acid resistance protein family ArAE_2_N PF10337.9 ABK73376.1 - 0.027 13.5 0.1 0.061 12.3 0.1 1.6 2 0 0 2 2 2 0 Putative ER transporter, 6TM, N-terminal ALMT PF11744.8 ABK73376.1 - 3 6.6 8.3 4.6 6.0 7.5 1.7 2 0 0 2 2 2 0 Aluminium activated malate transporter DnaJ_C PF01556.18 ABK73378.1 - 1.4e-38 132.3 0.0 1.8e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ABK73378.1 - 1.6e-25 88.9 0.1 2.3e-25 88.5 0.1 1.2 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 ABK73378.1 - 2.5e-12 47.0 12.6 4.2e-12 46.3 12.6 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 ABK73378.1 - 0.043 13.8 13.8 0.16 12.0 4.0 3.2 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Cytochrome_C7 PF14522.6 ABK73378.1 - 0.12 12.4 0.7 0.28 11.2 0.7 1.6 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c Lar_restr_allev PF14354.6 ABK73378.1 - 0.9 10.0 12.5 12 6.3 0.1 3.9 2 2 1 3 3 3 0 Restriction alleviation protein Lar DZR PF12773.7 ABK73378.1 - 5 7.2 7.5 13 6.0 6.7 2.0 1 1 1 2 2 2 0 Double zinc ribbon Lipase_GDSL_2 PF13472.6 ABK73379.1 - 2.3e-24 86.8 0.8 3e-24 86.4 0.8 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ABK73379.1 - 0.009 16.0 0.0 0.013 15.5 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Rho_RNA_bind PF07497.12 ABK73380.1 - 3.1e-28 97.4 0.2 6.9e-28 96.3 0.2 1.6 1 0 0 1 1 1 1 Rho termination factor, RNA-binding domain ATP-synt_ab PF00006.25 ABK73380.1 - 2e-25 89.7 0.0 3.1e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Rho_N PF07498.12 ABK73380.1 - 1.3e-12 47.4 0.1 2.7e-11 43.2 0.0 2.9 3 0 0 3 3 3 1 Rho termination factor, N-terminal domain AAA_25 PF13481.6 ABK73380.1 - 5.8e-05 22.8 0.0 0.00022 20.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 ABK73380.1 - 0.0078 16.1 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain FANC_SAP PF18081.1 ABK73380.1 - 0.06 13.5 1.0 0.75 10.0 0.8 2.7 2 1 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain CDC27 PF09507.10 ABK73380.1 - 4.7 6.5 24.7 6.6 6.0 24.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF3482 PF11981.8 ABK73381.1 - 0.11 11.9 0.1 0.15 11.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) DUF2976 PF11190.8 ABK73381.1 - 0.99 9.3 4.4 1.8 8.4 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2976) TPR_16 PF13432.6 ABK73382.1 - 3.2e-18 66.1 27.2 8.7e-09 35.9 7.0 4.4 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.6 ABK73382.1 - 2.7e-15 55.8 22.8 3.2e-06 27.5 0.5 5.7 2 1 4 6 6 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 ABK73382.1 - 1.9e-14 52.9 16.1 0.0044 17.3 0.1 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 ABK73382.1 - 4.5e-14 51.8 9.4 0.00015 21.3 0.5 4.0 3 1 1 4 4 4 3 TPR repeat TPR_19 PF14559.6 ABK73382.1 - 3.3e-13 49.9 18.3 1.8e-05 25.1 3.6 4.2 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 ABK73382.1 - 5.8e-13 47.9 19.9 0.0003 20.7 1.5 5.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 ABK73382.1 - 6.3e-13 47.8 4.3 3.6e-05 23.6 0.0 4.0 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 ABK73382.1 - 4.7e-11 42.0 11.1 0.0034 17.1 0.0 4.9 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 ABK73382.1 - 1.2e-08 35.0 15.0 5.5e-05 23.2 3.5 3.4 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 ABK73382.1 - 2.2e-08 33.7 12.4 1.9e-05 24.0 8.5 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ABK73382.1 - 6.5e-08 32.7 2.0 0.003 17.7 0.1 2.8 1 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 ABK73382.1 - 7.5e-06 26.2 10.8 1.4 9.3 0.3 4.3 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_21 PF09976.9 ABK73382.1 - 5.2e-05 23.0 5.4 0.0034 17.1 3.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat-like domain TPR_12 PF13424.6 ABK73382.1 - 0.00063 20.0 15.2 0.17 12.2 1.5 3.9 3 2 0 3 3 3 3 Tetratricopeptide repeat BTAD PF03704.17 ABK73382.1 - 0.00075 20.0 8.4 0.0033 17.9 0.4 3.0 2 2 0 2 2 2 1 Bacterial transcriptional activator domain TPR_7 PF13176.6 ABK73382.1 - 0.0027 17.6 6.6 0.11 12.6 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 ABK73382.1 - 0.011 16.2 2.5 11 6.4 0.1 3.4 2 2 2 4 4 4 0 Alkyl sulfatase dimerisation HrpB1_HrpK PF09613.10 ABK73382.1 - 0.022 14.4 0.2 0.095 12.3 0.1 2.1 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) NARP1 PF12569.8 ABK73382.1 - 0.036 13.0 0.3 0.3 10.0 0.0 2.0 1 1 0 2 2 2 0 NMDA receptor-regulated protein 1 Coatomer_E PF04733.14 ABK73382.1 - 0.054 12.9 1.1 0.77 9.1 0.0 2.6 1 1 2 3 3 3 0 Coatomer epsilon subunit TPR_6 PF13174.6 ABK73382.1 - 2.7 8.8 13.2 9.1 7.2 0.5 4.8 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 ABK73382.1 - 3.4 8.6 23.8 5.4 7.9 0.5 6.5 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF1254 PF06863.12 ABK73383.1 - 8.9e-43 145.6 0.1 2.1e-42 144.3 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1254) DUF1214 PF06742.11 ABK73383.1 - 1.3e-33 115.7 0.3 3.4e-33 114.4 0.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1214) Acyl-CoA_dh_1 PF00441.24 ABK73384.1 - 6.9e-43 146.4 6.3 6.9e-43 146.4 6.3 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK73384.1 - 3.1e-28 97.8 0.1 8.4e-28 96.4 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ABK73384.1 - 5.2e-26 91.5 2.0 8.1e-26 90.9 0.1 2.2 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ABK73384.1 - 2.1e-17 63.7 5.1 3.5e-17 62.9 5.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 ABK73384.1 - 0.0058 16.3 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal MetallophosN PF16371.5 ABK73385.1 - 0.0014 18.8 0.2 0.0034 17.6 0.2 1.6 1 0 0 1 1 1 1 N terminal of Calcineurin-like phosphoesterase DUF1416 PF07210.12 ABK73385.1 - 0.1 12.5 0.2 0.29 11.0 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1416) Peptidase_C26 PF07722.13 ABK73386.1 - 1.4e-54 185.1 0.0 1.7e-54 184.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase C26 GATase PF00117.28 ABK73386.1 - 9.5e-14 51.6 0.0 1.3e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I RNase_H PF00075.24 ABK73387.1 - 3e-48 163.7 0.0 3.5e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 RNase H SoxY PF13501.6 ABK73387.1 - 0.033 14.4 0.0 0.046 13.9 0.0 1.3 1 0 0 1 1 1 0 Sulfur oxidation protein SoxY RVT_3 PF13456.6 ABK73387.1 - 0.089 12.6 0.0 0.27 11.1 0.0 1.8 2 1 0 2 2 2 0 Reverse transcriptase-like Xan_ur_permease PF00860.20 ABK73388.1 - 2.9e-96 322.5 38.1 4.5e-96 321.9 38.1 1.3 1 0 0 1 1 1 1 Permease family OHCU_decarbox PF09349.10 ABK73388.1 - 4.5e-27 95.4 0.0 6.5e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 OHCU decarboxylase PNTB_4TM PF12769.7 ABK73388.1 - 0.27 11.7 5.7 1.7 9.2 0.6 3.3 2 2 0 2 2 2 0 4TM region of pyridine nucleotide transhydrogenase, mitoch PIN_8 PF18476.1 ABK73389.1 - 2.2e-52 178.2 2.6 2.2e-52 178.2 2.6 2.0 2 0 0 2 2 2 1 PIN like domain PIN_12 PF16289.5 ABK73389.1 - 7e-18 65.7 6.0 3e-17 63.6 1.5 2.9 2 1 0 2 2 2 1 PIN domain MFS_1 PF07690.16 ABK73390.1 - 9.4e-40 136.6 51.7 9.4e-40 136.6 51.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ABK73390.1 - 2.1e-07 30.6 51.5 2.7e-07 30.2 51.5 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Trp_syntA PF00290.20 ABK73390.1 - 0.24 10.2 1.2 0.26 10.1 0.1 1.6 2 0 0 2 2 2 0 Tryptophan synthase alpha chain TetR_N PF00440.23 ABK73392.1 - 7.6e-16 57.6 0.1 1.6e-15 56.6 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_15 PF17918.1 ABK73392.1 - 3.9e-12 46.9 10.7 3.9e-12 46.9 10.7 2.8 2 1 1 3 3 3 1 Tetracyclin repressor-like, C-terminal domain TetR_C_22 PF17928.1 ABK73392.1 - 0.00032 21.0 4.1 0.00049 20.4 3.2 1.8 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain AvrPtoB_bdg PF16847.5 ABK73392.1 - 0.042 14.3 2.7 0.24 11.9 0.3 2.7 1 1 2 3 3 3 0 Avirulence AvrPtoB, BAK1-binding domain V-ATPase_H_N PF03224.14 ABK73392.1 - 0.13 11.6 0.1 0.19 11.0 0.1 1.2 1 0 0 1 1 1 0 V-ATPase subunit H HhH-GPD PF00730.25 ABK73392.1 - 0.71 10.4 5.3 3.8 8.0 5.3 2.0 1 1 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein DUF4396 PF14342.6 ABK73393.1 - 0.027 14.8 5.9 0.034 14.5 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4396) DUF3043 PF11241.8 ABK73393.1 - 0.043 13.8 1.4 0.052 13.6 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Popeye PF04831.13 ABK73393.1 - 0.083 13.1 2.4 0.1 12.8 2.4 1.3 1 0 0 1 1 1 0 Popeye protein conserved region Trp_oprn_chp PF09534.10 ABK73393.1 - 0.2 11.4 4.9 0.26 11.1 4.9 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2207 PF09972.9 ABK73393.1 - 0.38 9.4 1.1 0.36 9.5 1.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3487 PF11990.8 ABK73393.1 - 1.1 9.2 5.3 0.37 10.7 2.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3487) DUF2721 PF11026.8 ABK73393.1 - 2.1 8.3 8.3 2.8 7.8 7.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) FtsX PF02687.21 ABK73394.1 - 1.1 9.8 6.1 2.3 8.8 6.1 1.5 1 1 0 1 1 1 0 FtsX-like permease family Oleosin PF01277.17 ABK73394.1 - 3.1 7.6 7.2 0.29 10.9 2.1 1.7 2 0 0 2 2 2 0 Oleosin HD PF01966.22 ABK73395.1 - 1.2e-12 48.1 0.2 1.4e-11 44.7 0.0 2.4 2 0 0 2 2 2 1 HD domain ACT PF01842.25 ABK73395.1 - 7.8e-09 35.2 0.5 0.0002 21.1 0.0 2.9 2 0 0 2 2 2 2 ACT domain GlnD_UR_UTase PF08335.11 ABK73395.1 - 8.7e-08 32.4 0.6 2.8e-06 27.5 0.6 2.5 1 1 0 1 1 1 1 GlnD PII-uridylyltransferase NTP_transf_2 PF01909.23 ABK73395.1 - 0.00063 20.0 0.0 0.0017 18.6 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain ACT_4 PF13291.6 ABK73395.1 - 0.00078 20.0 0.2 0.73 10.5 0.0 2.8 3 0 0 3 3 3 2 ACT domain ACT_6 PF13740.6 ABK73395.1 - 0.0013 18.7 1.6 0.12 12.4 0.1 3.4 3 0 0 3 3 3 1 ACT domain GlnE PF03710.15 ABK73395.1 - 0.0059 16.0 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 Glutamate-ammonia ligase adenylyltransferase DUF294 PF03445.13 ABK73395.1 - 0.085 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative nucleotidyltransferase DUF294 adh_short_C2 PF13561.6 ABK73396.1 - 5.1e-51 173.5 0.7 6.2e-51 173.2 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK73396.1 - 1.1e-40 139.2 0.1 1.4e-40 138.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK73396.1 - 1.5e-11 44.6 0.1 2e-11 44.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK73396.1 - 0.094 12.2 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF2771 PF10969.8 ABK73397.1 - 3e-48 163.8 0.0 3.3e-48 163.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2771) TetR_C_25 PF17933.1 ABK73399.1 - 3.1e-47 159.3 0.2 1.2e-46 157.3 0.1 1.9 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK73399.1 - 8.5e-14 51.1 0.1 1.4e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 ABK73399.1 - 0.00065 20.0 1.1 0.069 13.5 0.0 2.7 3 0 0 3 3 3 1 Tetracyclin repressor-like, C-terminal domain TetR_C_6 PF13977.6 ABK73399.1 - 0.0022 18.2 0.3 0.013 15.7 0.1 2.3 1 1 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal TetR_C_7 PF14246.6 ABK73399.1 - 0.059 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal domain LacI PF00356.21 ABK73399.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family Rieske PF00355.26 ABK73400.1 - 8.1e-13 48.1 0.0 1e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 ABK73400.1 - 1.9e-10 40.6 0.0 2.3e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain LPP20 PF02169.16 ABK73401.1 - 0.13 12.6 0.0 0.15 12.5 0.0 1.0 1 0 0 1 1 1 0 LPP20 lipoprotein AA_permease_2 PF13520.6 ABK73402.1 - 9.1e-45 153.2 36.7 1.3e-44 152.7 36.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ABK73402.1 - 4.2e-31 108.1 36.1 5.8e-31 107.6 36.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 ABK73402.1 - 0.00038 20.5 1.4 0.00038 20.5 1.4 3.5 5 0 0 5 5 5 1 C-terminus of AA_permease Spore_permease PF03845.13 ABK73402.1 - 0.1 11.4 19.7 0.054 12.3 4.3 3.0 1 1 0 2 2 2 0 Spore germination protein SHOCT PF09851.9 ABK73403.1 - 0.0045 16.7 0.0 0.0073 16.0 0.0 1.4 1 0 0 1 1 1 1 Short C-terminal domain Phage_holin_3_6 PF07332.11 ABK73403.1 - 0.16 12.0 5.9 0.14 12.2 4.1 1.7 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III adh_short PF00106.25 ABK73404.1 - 6.4e-45 153.0 0.0 4.4e-44 150.3 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK73404.1 - 2e-35 122.5 0.1 1.3e-34 119.8 0.0 1.9 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK73404.1 - 1.3e-09 38.2 0.7 3.3e-09 36.9 0.3 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 ABK73404.1 - 6.9e-05 22.4 0.1 0.00013 21.5 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ABK73404.1 - 0.00016 21.6 0.1 0.00028 20.9 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_7 PF13241.6 ABK73404.1 - 0.001 19.4 0.1 0.0018 18.7 0.1 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.19 ABK73404.1 - 0.0047 16.3 0.0 0.017 14.4 0.0 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.8 ABK73404.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.17 ABK73404.1 - 0.036 13.2 1.7 0.052 12.6 0.1 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain 2-Hacid_dh_C PF02826.19 ABK73404.1 - 0.038 13.3 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 ABK73404.1 - 0.041 13.3 0.0 0.061 12.7 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 ABK73404.1 - 0.1 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DFP PF04127.15 ABK73404.1 - 0.1 12.4 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Aldo_ket_red PF00248.21 ABK73405.1 - 1.7e-63 214.6 0.0 3.5e-62 210.3 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family PUA PF01472.20 ABK73405.1 - 0.089 12.8 0.2 2.6 8.1 0.0 2.6 2 1 1 3 3 3 0 PUA domain p450 PF00067.22 ABK73406.1 - 3.7e-70 237.0 0.0 4.9e-70 236.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 COesterase PF00135.28 ABK73407.1 - 1.4e-98 331.0 0.0 9e-98 328.4 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ABK73407.1 - 2.6e-08 34.0 1.5 2.7e-06 27.4 0.3 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold NAD_binding_10 PF13460.6 ABK73408.1 - 3.5e-43 147.6 8.2 4e-43 147.5 8.2 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ABK73408.1 - 3.7e-11 43.0 0.1 6.4e-11 42.3 0.1 1.5 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 ABK73408.1 - 5.4e-06 26.0 0.2 2.4e-05 23.9 0.1 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 ABK73408.1 - 0.0029 16.8 0.0 0.0068 15.6 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein Ldh_1_N PF00056.23 ABK73408.1 - 0.094 12.8 1.6 0.18 11.9 1.6 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain TrkA_N PF02254.18 ABK73408.1 - 0.12 12.6 3.0 0.25 11.6 3.0 1.7 1 1 0 1 1 1 0 TrkA-N domain RmlD_sub_bind PF04321.17 ABK73408.1 - 0.12 11.4 2.7 0.26 10.4 2.5 1.7 1 1 0 1 1 1 0 RmlD substrate binding domain FxsA PF04186.13 ABK73409.1 - 6.2e-22 77.8 15.0 8.3e-22 77.4 15.0 1.1 1 0 0 1 1 1 1 FxsA cytoplasmic membrane protein Bac_luciferase PF00296.20 ABK73410.1 - 2.7e-64 217.6 8.4 3.2e-64 217.3 8.4 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase NIR_SIR PF01077.22 ABK73410.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain UvrA_inter PF17760.1 ABK73411.1 - 4.4e-40 136.1 0.2 1.1e-39 134.8 0.2 1.7 1 0 0 1 1 1 1 UvrA interaction domain UvrA_DNA-bind PF17755.1 ABK73411.1 - 6.1e-36 123.1 0.0 1.6e-33 115.4 0.0 3.5 4 0 0 4 4 3 1 UvrA DNA-binding domain ABC_tran PF00005.27 ABK73411.1 - 7.5e-18 65.4 0.0 7.1e-09 36.3 0.0 4.7 3 2 0 3 3 3 3 ABC transporter AAA_16 PF13191.6 ABK73411.1 - 1.8e-07 31.7 0.4 0.027 14.8 0.0 3.1 3 1 0 3 3 2 2 AAA ATPase domain SMC_N PF02463.19 ABK73411.1 - 2.5e-07 30.3 0.0 0.054 12.9 0.0 4.1 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ABK73411.1 - 3.1e-07 30.0 0.4 0.0076 16.0 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 ABK73411.1 - 3.1e-05 23.9 2.9 0.0077 16.1 0.0 3.6 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ABK73411.1 - 4.4e-05 23.5 0.1 0.067 13.1 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 ABK73411.1 - 6.9e-05 22.5 0.1 0.38 10.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain APS_kinase PF01583.20 ABK73411.1 - 0.00028 20.8 0.2 0.51 10.2 0.0 2.7 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_33 PF13671.6 ABK73411.1 - 0.00076 19.7 0.1 2.1 8.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain DnaJ_CXXCXGXG PF00684.19 ABK73411.1 - 0.0025 18.1 5.5 0.13 12.6 0.2 3.6 4 0 0 4 4 3 1 DnaJ central domain BCA_ABC_TP_C PF12399.8 ABK73411.1 - 0.004 17.0 0.1 0.067 13.1 0.3 2.6 2 0 0 2 2 2 1 Branched-chain amino acid ATP-binding cassette transporter AAA_23 PF13476.6 ABK73411.1 - 0.0049 17.4 0.0 1.2 9.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ABK73411.1 - 0.0063 17.0 0.0 5.1 7.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 ABK73411.1 - 0.0078 16.0 0.0 4.4 6.9 0.0 3.1 4 0 0 4 4 3 1 AAA ATPase domain AAA_22 PF13401.6 ABK73411.1 - 0.01 16.1 0.0 4.4 7.6 0.0 3.1 3 0 0 3 3 2 0 AAA domain Viral_helicase1 PF01443.18 ABK73411.1 - 0.029 14.1 0.0 0.24 11.1 0.0 2.3 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 ABK73411.1 - 0.042 13.8 0.2 2.4 8.0 0.0 2.8 3 0 0 3 3 2 0 NACHT domain T2SSE PF00437.20 ABK73411.1 - 0.054 12.6 0.2 1.4 7.9 0.1 2.5 3 0 0 3 3 3 0 Type II/IV secretion system protein RNA_helicase PF00910.22 ABK73411.1 - 0.073 13.5 0.0 4.2 7.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase cobW PF02492.19 ABK73411.1 - 0.084 12.4 2.0 1.2 8.7 0.3 2.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain DUF1421 PF07223.11 ABK73411.1 - 0.087 12.7 0.0 0.28 11.1 0.0 2.0 1 0 0 1 1 1 0 UBA-like domain (DUF1421) SRP54 PF00448.22 ABK73411.1 - 0.13 11.9 0.0 0.57 9.8 0.0 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ATPase PF06745.13 ABK73411.1 - 0.13 11.6 0.0 2.5 7.4 0.0 2.5 2 0 0 2 2 2 0 KaiC PRK PF00485.18 ABK73411.1 - 0.14 11.9 0.1 5.6 6.6 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Zn-ribbon_8 PF09723.10 ABK73411.1 - 0.14 12.3 10.0 12 6.1 0.0 4.7 4 1 0 4 4 4 0 Zinc ribbon domain HTH_IclR PF09339.10 ABK73411.1 - 0.14 12.0 0.3 0.51 10.2 0.0 2.1 2 0 0 2 2 2 0 IclR helix-turn-helix domain AAA_14 PF13173.6 ABK73411.1 - 0.19 11.8 0.0 21 5.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain DNA_ligase_ZBD PF03119.16 ABK73411.1 - 0.39 10.8 6.0 0.31 11.1 0.1 3.2 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain Gln-synt_C PF00120.24 ABK73413.1 - 2.6e-68 230.6 0.0 4.4e-68 229.8 0.0 1.3 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain ECH_1 PF00378.20 ABK73414.1 - 1.5e-41 142.4 0.0 1.6e-41 142.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK73414.1 - 1.4e-19 70.8 0.0 2e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF167 PF02594.16 ABK73414.1 - 0.02 15.0 0.0 7.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised ACR, YggU family COG1872 DUF1622 PF07784.11 ABK73414.1 - 0.15 12.0 0.1 0.31 11.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1622) Polyketide_cyc2 PF10604.9 ABK73415.1 - 5.5e-17 62.4 0.1 6.1e-17 62.2 0.1 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport MatC_N PF07158.11 ABK73416.1 - 2.7e-60 202.8 16.9 2.7e-60 202.8 16.9 2.5 2 0 0 2 2 2 1 Dicarboxylate carrier protein MatC N-terminus CitMHS PF03600.16 ABK73416.1 - 1e-26 93.9 83.9 9.2e-21 74.3 51.7 2.1 1 1 1 2 2 2 2 Citrate transporter WXG100 PF06013.12 ABK73417.1 - 6.4e-10 39.1 5.3 8.6e-10 38.7 3.0 2.3 1 1 1 2 2 2 1 Proteins of 100 residues with WXG Abhydrolase_8 PF06259.12 ABK73417.1 - 7.2e-09 35.5 3.9 1e-07 31.8 0.8 3.2 2 1 0 2 2 2 1 Alpha/beta hydrolase Abhydrolase_1 PF00561.20 ABK73417.1 - 0.075 12.7 0.1 0.21 11.2 0.1 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold HBM PF16591.5 ABK73417.1 - 5.4 6.4 9.4 0.13 11.7 1.9 2.0 3 0 0 3 3 3 0 Helical bimodular sensor domain HrpB7 PF09486.10 ABK73417.1 - 6 7.2 9.6 6.8 7.1 1.3 2.6 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Methyltransf_25 PF13649.6 ABK73418.1 - 0.0079 16.9 0.0 0.016 15.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cupin_2 PF07883.11 ABK73419.1 - 5e-12 45.4 0.0 8.7e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 Cupin domain HTH_26 PF13443.6 ABK73419.1 - 7e-12 45.6 0.0 1.1e-11 45.0 0.0 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_31 PF13560.6 ABK73419.1 - 4.6e-11 42.9 0.2 7.9e-11 42.1 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 ABK73419.1 - 1.5e-09 37.8 0.0 2.1e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 ABK73419.1 - 5.9e-07 29.4 0.0 8.8e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Cupin_3 PF05899.12 ABK73419.1 - 0.0011 18.6 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) AraC_binding PF02311.19 ABK73419.1 - 0.0041 17.0 0.0 0.0061 16.5 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain HTH_25 PF13413.6 ABK73419.1 - 0.0052 16.6 0.0 0.0095 15.8 0.0 1.5 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 ABK73419.1 - 0.017 15.1 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain AraC_binding_2 PF14525.6 ABK73419.1 - 0.035 13.8 0.1 0.071 12.8 0.1 1.6 1 0 0 1 1 1 0 AraC-binding-like domain HutD PF05962.11 ABK73419.1 - 0.11 12.5 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 HutD Glu_synthase PF01645.17 ABK73420.1 - 4e-85 286.2 0.9 6e-80 269.1 1.0 2.0 2 0 0 2 2 2 2 Conserved region in glutamate synthase FMN_dh PF01070.18 ABK73420.1 - 1.5e-17 63.7 2.7 1.2e-16 60.8 1.5 2.4 3 0 0 3 3 3 1 FMN-dependent dehydrogenase NMO PF03060.15 ABK73420.1 - 2.1e-12 47.1 1.8 3.8e-12 46.2 1.8 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 ABK73420.1 - 5.8e-12 45.3 2.2 1.1e-11 44.4 2.2 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 ABK73420.1 - 7.8e-05 22.2 0.8 0.00019 21.0 0.4 1.7 1 1 0 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 ABK73420.1 - 0.0011 18.3 0.3 0.0023 17.3 0.3 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 ABK73420.1 - 0.0018 17.5 0.3 0.0018 17.5 0.3 1.5 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase Glu_syn_central PF04898.14 ABK73420.1 - 0.0029 17.1 0.3 0.0046 16.5 0.3 1.2 1 0 0 1 1 1 1 Glutamate synthase central domain QRPTase_C PF01729.19 ABK73420.1 - 0.0051 16.6 0.0 0.0087 15.9 0.0 1.3 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain LrgB PF04172.16 ABK73420.1 - 0.077 12.5 0.9 0.13 11.8 0.9 1.3 1 0 0 1 1 1 0 LrgB-like family PcrB PF01884.17 ABK73420.1 - 0.1 12.0 3.3 0.25 10.8 0.8 2.2 1 1 1 2 2 2 0 PcrB family G3P_antiterm PF04309.12 ABK73420.1 - 0.2 11.1 1.8 0.18 11.2 0.2 1.7 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator UPF0016 PF01169.19 ABK73421.1 - 8.4e-43 144.6 30.3 1.2e-21 76.9 9.8 3.0 3 0 0 3 3 3 2 Uncharacterized protein family UPF0016 TauE PF01925.19 ABK73421.1 - 0.014 15.1 25.4 0.14 11.8 6.5 2.4 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE MFS_1 PF07690.16 ABK73421.1 - 0.017 14.0 24.8 0.009 15.0 18.6 2.1 1 1 1 2 2 2 0 Major Facilitator Superfamily Wzz PF02706.15 ABK73421.1 - 1 9.7 2.8 4 7.8 0.1 2.8 2 0 0 2 2 2 0 Chain length determinant protein Vma12 PF11712.8 ABK73421.1 - 1.5 8.8 2.8 6.6 6.8 1.0 2.2 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase 2-Hacid_dh_C PF02826.19 ABK73422.1 - 8.2e-63 211.0 0.0 1.8e-62 209.9 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ABK73422.1 - 9.4e-37 125.7 0.6 1.6e-36 124.9 0.6 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 ABK73422.1 - 2.5e-08 33.5 0.4 1.4e-07 31.1 0.1 2.4 2 0 0 2 2 2 1 ACT domain NAD_binding_2 PF03446.15 ABK73422.1 - 4.9e-06 26.8 0.1 2.6e-05 24.5 0.1 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 ABK73422.1 - 0.00073 19.1 0.1 0.0017 18.0 0.1 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 ABK73422.1 - 0.0015 18.6 0.3 0.18 11.8 0.0 2.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 ABK73422.1 - 0.0021 18.6 3.6 0.0023 18.5 0.2 2.8 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 ABK73422.1 - 0.0028 17.5 0.9 0.0028 17.5 0.9 2.9 4 1 1 5 5 5 1 Rossmann-like domain 3HCDH_N PF02737.18 ABK73422.1 - 0.0049 16.8 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 ABK73422.1 - 0.0071 16.4 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.6 ABK73422.1 - 0.011 16.1 0.1 0.098 13.1 0.1 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding UDPG_MGDP_dh_C PF03720.15 ABK73422.1 - 0.018 15.5 0.0 0.06 13.8 0.0 1.9 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain GFO_IDH_MocA PF01408.22 ABK73422.1 - 0.039 14.8 0.2 0.4 11.5 0.0 2.6 3 0 0 3 3 3 0 Oxidoreductase family, NAD-binding Rossmann fold ACT_4 PF13291.6 ABK73422.1 - 0.046 14.3 0.0 0.18 12.4 0.0 2.0 1 0 0 1 1 1 0 ACT domain TrkA_N PF02254.18 ABK73422.1 - 0.053 13.8 1.5 0.26 11.6 0.0 2.9 3 0 0 3 3 3 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 ABK73422.1 - 0.23 11.7 6.5 0.41 10.9 0.1 3.6 3 1 1 4 4 4 0 Saccharopine dehydrogenase NADP binding domain BAT PF15915.5 ABK73422.1 - 0.44 10.4 13.2 0.24 11.3 0.3 3.3 3 0 0 3 3 3 0 GAF and HTH_10 associated domain MMPL PF03176.15 ABK73423.1 - 4.4e-183 607.7 23.3 1.8e-98 329.6 4.2 2.9 3 0 0 3 3 3 2 MMPL family ACR_tran PF00873.19 ABK73423.1 - 0.52 7.9 25.1 0.042 11.5 5.6 2.3 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family ILVD_EDD PF00920.21 ABK73424.1 - 1.2e-210 700.5 3.0 1.4e-210 700.3 3.0 1.0 1 0 0 1 1 1 1 Dehydratase family SHOCT PF09851.9 ABK73424.1 - 0.57 10.0 3.1 2.5 7.9 0.4 3.0 3 0 0 3 3 3 0 Short C-terminal domain DeoC PF01791.9 ABK73425.1 - 3.2e-17 62.9 5.4 3.9e-17 62.7 5.4 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase DHO_dh PF01180.21 ABK73425.1 - 0.0053 16.0 1.0 0.0074 15.5 0.3 1.6 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase His_biosynth PF00977.21 ABK73425.1 - 0.0089 15.5 1.0 0.019 14.5 0.1 1.9 2 0 0 2 2 2 1 Histidine biosynthesis protein Dus PF01207.17 ABK73425.1 - 0.2 10.7 0.5 0.4 9.7 0.5 1.5 1 1 0 1 1 1 0 Dihydrouridine synthase (Dus) Thioredoxin_4 PF13462.6 ABK73427.1 - 2.7e-07 30.9 0.0 7.3e-07 29.5 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.20 ABK73427.1 - 0.0044 16.8 0.3 0.24 11.1 0.3 2.6 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Glutaredoxin PF00462.24 ABK73427.1 - 0.046 14.0 0.0 2 8.7 0.0 2.3 2 0 0 2 2 2 0 Glutaredoxin NPCBM_assoc PF10633.9 ABK73428.1 - 0.017 15.3 1.9 0.052 13.8 0.1 2.5 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Nitrate_red_gam PF02665.14 ABK73429.1 - 1.4e-88 296.1 14.9 1.7e-88 295.8 14.9 1.0 1 0 0 1 1 1 1 Nitrate reductase gamma subunit UPF0016 PF01169.19 ABK73429.1 - 2 8.8 9.2 37 4.7 5.2 3.2 1 1 2 3 3 3 0 Uncharacterized protein family UPF0016 p450 PF00067.22 ABK73430.1 - 7.8e-25 87.5 0.0 3.9e-16 58.9 0.0 3.0 2 1 0 2 2 2 2 Cytochrome P450 GrpB PF04229.14 ABK73431.1 - 6.5e-51 172.7 0.0 7.5e-51 172.5 0.0 1.0 1 0 0 1 1 1 1 GrpB protein APH PF01636.23 ABK73432.1 - 1.5e-19 70.9 1.4 2e-19 70.5 1.4 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 ABK73432.1 - 2.2e-15 56.7 0.0 4.2e-12 46.0 0.0 2.4 2 1 0 2 2 2 2 Ecdysteroid kinase DUF1679 PF07914.11 ABK73432.1 - 8.7e-09 34.7 0.0 1.5e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) APH_6_hur PF04655.14 ABK73432.1 - 0.035 13.5 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase HC2 PF07382.11 ABK73433.1 - 4.9e-05 23.5 36.7 6.5e-05 23.1 36.7 1.1 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 DUF1631 PF07793.11 ABK73433.1 - 9.8 4.4 11.2 12 4.2 11.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) HTH_30 PF13556.6 ABK73434.1 - 1.3e-16 60.1 0.0 4.7e-16 58.3 0.0 2.0 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_1 PF00126.27 ABK73434.1 - 0.0036 17.2 0.1 0.037 14.0 0.0 2.6 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_28 PF13518.6 ABK73434.1 - 0.019 15.1 0.0 0.12 12.6 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 ABK73434.1 - 0.029 14.2 0.1 0.2 11.5 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain Bac_luciferase PF00296.20 ABK73435.1 - 2.6e-58 197.9 7.1 6.6e-58 196.6 7.1 1.5 1 1 0 1 1 1 1 Luciferase-like monooxygenase FliT PF05400.13 ABK73435.1 - 0.023 15.5 0.2 0.13 13.1 0.1 2.2 2 0 0 2 2 2 0 Flagellar protein FliT Aldedh PF00171.22 ABK73436.1 - 1.6e-142 475.3 0.0 1.8e-142 475.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PAS_8 PF13188.7 ABK73436.1 - 0.05 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 PAS domain MspA PF09203.11 ABK73437.1 - 8.3e-40 136.5 0.1 1.1e-39 136.1 0.1 1.1 1 0 0 1 1 1 1 MspA YbjN PF10722.9 ABK73438.1 - 2.8e-26 92.1 0.0 3.5e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Putative bacterial sensory transduction regulator CesT PF05932.13 ABK73438.1 - 0.026 14.6 0.0 0.036 14.2 0.0 1.2 1 0 0 1 1 1 0 Tir chaperone protein (CesT) family GCS2 PF04107.13 ABK73440.1 - 1.7e-48 165.4 0.2 2.3e-48 165.0 0.2 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) Ribosomal_L28 PF00830.19 ABK73441.1 - 1.2e-24 86.2 0.1 1.4e-24 86.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal L28 family AAA_lid_10 PF17872.1 ABK73441.1 - 0.13 12.4 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 AAA lid domain DUF5313 PF17240.2 ABK73443.1 - 4.5e-58 195.0 3.1 5.1e-58 194.9 3.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5313) MerR-DNA-bind PF09278.11 ABK73444.1 - 3.1e-17 62.9 0.4 4.7e-17 62.3 0.4 1.3 1 0 0 1 1 1 1 MerR, DNA binding MerR_1 PF13411.6 ABK73444.1 - 2.6e-15 56.3 0.1 3.7e-15 55.7 0.1 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 ABK73444.1 - 8.3e-15 54.3 1.9 1.6e-14 53.3 0.5 2.0 2 0 0 2 2 2 1 MerR family regulatory protein HTH_IclR PF09339.10 ABK73444.1 - 0.012 15.4 0.2 4.6 7.1 0.0 2.4 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_24 PF13412.6 ABK73444.1 - 0.031 13.8 0.0 2.8 7.6 0.0 2.6 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding MerR_2 PF13591.6 ABK73444.1 - 0.14 12.1 0.1 0.26 11.2 0.0 1.5 2 0 0 2 2 2 0 MerR HTH family regulatory protein Usp PF00582.26 ABK73445.1 - 1.7e-23 83.7 4.7 2.2e-12 47.7 1.0 2.1 2 0 0 2 2 2 2 Universal stress protein family FAD_binding_3 PF01494.19 ABK73446.1 - 2.4e-13 50.1 0.5 3.2e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ABK73446.1 - 1.1e-05 25.5 0.0 2.7e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ABK73446.1 - 0.0063 15.8 0.1 0.031 13.5 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ABK73446.1 - 0.053 12.8 0.0 9.2 5.4 0.0 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase DAO PF01266.24 ABK73446.1 - 0.057 13.0 3.0 0.22 11.0 3.0 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 ABK73446.1 - 0.11 13.0 0.0 0.22 12.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ABK73446.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF2282 PF10048.9 ABK73446.1 - 0.23 11.5 0.5 0.43 10.6 0.5 1.4 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2282) Hydantoinase_B PF02538.14 ABK73447.1 - 7e-147 489.9 0.1 8.3e-147 489.7 0.1 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase MoaE PF02391.17 ABK73448.1 - 2.7e-35 121.0 1.5 3.1e-35 120.8 1.5 1.0 1 0 0 1 1 1 1 MoaE protein acVLRF1 PF18859.1 ABK73448.1 - 0.021 15.1 2.0 0.028 14.7 2.0 1.2 1 0 0 1 1 1 0 Actinobacteria/chloroflexi VLRF1 release factor HHA PF05321.11 ABK73448.1 - 0.11 12.8 1.1 0.91 9.9 0.2 2.3 1 1 1 2 2 2 0 Haemolysin expression modulating protein DUF3325 PF11804.8 ABK73449.1 - 0.046 13.9 8.6 0.057 13.6 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3325) MerC PF03203.14 ABK73449.1 - 0.066 13.7 4.1 0.08 13.4 4.1 1.1 1 0 0 1 1 1 0 MerC mercury resistance protein SLATT_1 PF18181.1 ABK73449.1 - 0.52 10.3 6.9 0.65 9.9 6.9 1.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 DUF2892 PF11127.8 ABK73449.1 - 1.2 9.2 7.5 1.6 8.8 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) DUF4131 PF13567.6 ABK73449.1 - 1.3 8.7 4.4 1.8 8.2 4.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) CbiQ PF02361.16 ABK73450.1 - 7e-30 104.3 5.3 1.1e-29 103.6 5.3 1.2 1 0 0 1 1 1 1 Cobalt transport protein BPD_transp_1 PF00528.22 ABK73451.1 - 8.1e-21 74.6 16.1 8.1e-21 74.6 16.1 1.5 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component DUF1656 PF07869.12 ABK73451.1 - 0.023 14.7 1.8 0.023 14.7 1.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) Wzz PF02706.15 ABK73451.1 - 0.045 14.1 2.1 0.045 14.1 2.1 2.1 2 0 0 2 2 2 0 Chain length determinant protein SPC25 PF06703.11 ABK73451.1 - 0.13 12.1 1.3 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) SK_channel PF03530.14 ABK73451.1 - 0.13 12.3 1.8 0.5 10.4 0.1 2.1 2 0 0 2 2 2 0 Calcium-activated SK potassium channel FtsX PF02687.21 ABK73451.1 - 0.43 11.1 9.6 4.5 7.8 0.7 2.5 2 0 0 2 2 2 0 FtsX-like permease family DUF997 PF06196.12 ABK73451.1 - 0.96 9.5 6.3 1.9 8.6 4.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF997) Amnionless PF14828.6 ABK73451.1 - 5.7 5.6 4.5 2.1 7.1 1.5 1.7 2 0 0 2 2 2 0 Amnionless WES_acyltransf PF03007.16 ABK73452.1 - 0.00035 20.4 2.0 0.00093 19.0 1.0 2.2 2 0 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 ABK73452.1 - 0.031 14.2 0.0 0.054 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) DUF3097 PF11296.8 ABK73453.1 - 7.6e-125 415.6 1.4 8.5e-125 415.4 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3097) AhpC-TSA PF00578.21 ABK73454.1 - 1.6e-32 112.0 0.0 1.9e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ABK73454.1 - 2e-20 73.0 0.0 2.2e-20 72.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 ABK73454.1 - 2.6e-05 24.3 0.0 3.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF899 PF05988.12 ABK73454.1 - 0.1 12.1 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) DapB_N PF01113.20 ABK73455.1 - 5.7e-06 26.5 0.0 9.6e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 ABK73455.1 - 0.00032 21.5 0.0 0.00056 20.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 ABK73455.1 - 0.00058 20.3 0.0 0.0012 19.3 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 ABK73455.1 - 0.00082 19.3 0.1 0.0015 18.4 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding F420_oxidored PF03807.17 ABK73455.1 - 0.03 14.9 0.0 0.064 13.8 0.0 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2Fe-2S_Ferredox PF11591.8 ABK73455.1 - 0.51 10.2 3.3 1.6 8.6 3.3 1.8 1 0 0 1 1 1 0 Ferredoxin chloroplastic transit peptide Amino_oxidase PF01593.24 ABK73456.1 - 6.5e-66 223.5 0.6 7.4e-66 223.3 0.6 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ABK73456.1 - 1.3e-14 54.1 1.1 3.4e-14 52.8 1.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ABK73456.1 - 1.4e-10 41.3 9.5 5.8e-10 39.3 9.5 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ABK73456.1 - 7.8e-07 28.5 2.3 1.5e-06 27.6 2.3 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 ABK73456.1 - 1.3e-06 28.1 0.1 1.7e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ABK73456.1 - 1.8e-06 27.4 1.4 1.8e-06 27.4 1.4 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ABK73456.1 - 7e-06 25.0 0.6 0.00065 18.5 0.3 2.1 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.17 ABK73456.1 - 3.2e-05 23.3 0.3 5.6e-05 22.5 0.3 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 ABK73456.1 - 4.8e-05 23.8 1.6 0.00053 20.5 1.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ABK73456.1 - 0.0002 20.7 1.3 0.00038 19.8 1.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 ABK73456.1 - 0.00032 20.1 0.2 0.11 11.7 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ABK73456.1 - 0.00037 19.8 1.0 0.00058 19.2 1.0 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 ABK73456.1 - 0.00071 18.8 0.6 0.0011 18.2 0.6 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 ABK73456.1 - 0.0008 18.6 0.9 0.0041 16.2 0.2 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 ABK73456.1 - 0.21 11.6 1.7 0.36 10.8 0.3 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Bac_luciferase PF00296.20 ABK73458.1 - 3.4e-64 217.2 6.2 5.2e-64 216.7 6.2 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase Aldo_ket_red PF00248.21 ABK73459.1 - 8e-69 232.1 0.0 9e-69 231.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RHH_1 PF01402.21 ABK73459.1 - 0.3 11.1 3.2 2 8.5 0.0 3.4 4 0 0 4 4 4 0 Ribbon-helix-helix protein, copG family TP_methylase PF00590.20 ABK73460.1 - 9.5e-30 104.1 0.1 1.2e-29 103.9 0.1 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Tk-SP_N-pro PF18237.1 ABK73460.1 - 0.24 11.5 0.0 0.41 10.7 0.0 1.3 1 0 0 1 1 1 0 Tk-SP N-propeptide domain TetR_N PF00440.23 ABK73461.1 - 2.5e-17 62.4 0.3 5.6e-17 61.3 0.3 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 ABK73461.1 - 0.008 16.4 7.0 0.0082 16.4 2.0 2.6 2 1 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal TetR_C_31 PF17940.1 ABK73461.1 - 0.023 14.9 3.5 0.023 14.9 3.5 2.5 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain PRiA4_ORF3 PF07929.11 ABK73462.1 - 2.1e-51 174.1 0.0 2.5e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein DAO PF01266.24 ABK73463.1 - 7.6e-45 154.0 3.6 9.8e-45 153.6 3.6 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ABK73463.1 - 8.1e-07 28.6 5.8 0.00019 20.8 0.3 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ABK73463.1 - 1.4e-06 27.8 4.1 1.4e-05 24.6 4.1 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ABK73463.1 - 4.7e-06 26.7 3.1 1.9e-05 24.8 2.9 2.1 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Rieske PF00355.26 ABK73463.1 - 6e-06 26.1 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Amino_oxidase PF01593.24 ABK73463.1 - 3.9e-05 23.1 0.2 0.049 12.9 0.3 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 ABK73463.1 - 7.9e-05 21.5 1.8 0.016 13.9 2.4 2.3 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 ABK73463.1 - 0.00018 20.7 6.5 0.00071 18.8 6.5 1.9 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 ABK73463.1 - 0.00039 19.7 0.5 0.00067 19.0 0.5 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 ABK73463.1 - 0.00051 19.5 1.7 0.00051 19.5 1.7 2.4 4 0 0 4 4 4 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 ABK73463.1 - 0.013 14.4 0.2 0.017 14.0 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 ABK73463.1 - 0.025 14.6 0.3 1.7 8.6 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 ABK73463.1 - 0.042 12.9 1.4 0.071 12.2 1.4 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.14 ABK73463.1 - 0.11 12.1 1.1 0.17 11.5 1.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 ABK73463.1 - 0.24 11.0 1.0 0.44 10.2 1.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 ABK73463.1 - 0.85 9.5 3.8 2.2 8.1 3.7 1.6 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 ABK73463.1 - 0.87 10.2 5.7 0.45 11.1 2.5 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ABK73463.1 - 0.98 8.6 2.5 1.3 8.2 1.5 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RNase_PH PF01138.21 ABK73464.1 - 4.8e-39 133.9 0.0 3.1e-18 66.6 0.0 2.6 3 0 0 3 3 3 2 3' exoribonuclease family, domain 1 PNPase PF03726.14 ABK73464.1 - 1.3e-21 76.9 0.8 3.2e-21 75.6 0.8 1.8 1 0 0 1 1 1 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain S1 PF00575.23 ABK73464.1 - 1.9e-14 53.8 1.1 4.5e-14 52.5 1.1 1.7 1 0 0 1 1 1 1 S1 RNA binding domain KH_1 PF00013.29 ABK73464.1 - 7.2e-11 41.8 0.9 2.2e-10 40.2 0.9 1.9 1 0 0 1 1 1 1 KH domain RNase_PH_C PF03725.15 ABK73464.1 - 6.1e-08 32.6 1.4 0.0059 16.6 0.1 3.2 2 0 0 2 2 2 2 3' exoribonuclease family, domain 2 KH_2 PF07650.17 ABK73464.1 - 0.0013 18.6 0.1 0.0038 17.0 0.1 1.8 1 0 0 1 1 1 1 KH domain KH_5 PF13184.6 ABK73464.1 - 0.1 12.7 0.4 0.41 10.7 0.4 2.0 1 0 0 1 1 1 0 NusA-like KH domain DUF1490 PF07371.12 ABK73464.1 - 0.16 12.1 0.0 0.16 12.1 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1490) KH_4 PF13083.6 ABK73464.1 - 0.23 11.3 2.7 0.55 10.2 0.0 2.8 3 0 0 3 3 3 0 KH domain Ribosomal_L33 PF00471.20 ABK73465.1 - 5.4e-22 78.0 4.7 6e-22 77.8 4.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L33 zinc_ribbon_2 PF13240.6 ABK73465.1 - 0.0065 16.2 0.5 0.0065 16.2 0.5 2.0 2 0 0 2 2 2 1 zinc-ribbon domain zf-Sec23_Sec24 PF04810.15 ABK73465.1 - 0.012 15.6 1.2 0.05 13.6 0.0 2.0 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-ribbon_3 PF13248.6 ABK73465.1 - 0.014 14.8 2.4 0.03 13.7 0.5 2.0 2 0 0 2 2 2 0 zinc-ribbon domain A2L_zn_ribbon PF08792.10 ABK73465.1 - 0.015 15.0 2.3 0.76 9.6 0.2 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain RNA_POL_M_15KD PF02150.16 ABK73465.1 - 0.02 14.7 1.9 1.9 8.4 0.5 2.2 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf-NADH-PPase PF09297.11 ABK73465.1 - 0.033 13.8 1.9 0.28 10.9 0.1 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DZR PF12773.7 ABK73465.1 - 0.04 14.0 2.9 0.086 12.9 2.9 1.6 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 ABK73465.1 - 0.047 13.7 0.8 0.055 13.5 0.8 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TF_Zn_Ribbon PF08271.12 ABK73465.1 - 0.062 12.8 2.7 0.18 11.3 2.8 1.7 1 1 0 1 1 1 0 TFIIB zinc-binding Nudix_N_2 PF14803.6 ABK73465.1 - 0.16 11.9 4.2 0.22 11.5 0.7 2.2 2 0 0 2 2 2 0 Nudix N-terminal GFA PF04828.14 ABK73465.1 - 0.17 12.2 2.4 0.72 10.2 0.3 2.0 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.11 ABK73465.1 - 0.19 11.9 4.4 0.35 11.0 4.4 1.5 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Whib PF02467.16 ABK73466.1 - 9.5e-24 83.8 1.2 1.1e-23 83.5 1.2 1.1 1 0 0 1 1 1 1 Transcription factor WhiB Polyketide_cyc2 PF10604.9 ABK73467.1 - 1.2e-16 61.2 0.2 1.6e-16 60.9 0.2 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 ABK73467.1 - 4.8e-11 43.0 0.0 7.1e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 ABK73467.1 - 0.0014 18.9 0.0 0.0021 18.2 0.0 1.3 1 1 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein DUF2505 PF10698.9 ABK73467.1 - 0.059 13.5 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2505) GerE PF00196.19 ABK73468.1 - 2e-17 62.4 0.1 1.3e-16 59.9 0.0 2.2 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family AAA_16 PF13191.6 ABK73468.1 - 4.1e-16 59.8 0.6 4.1e-16 59.8 0.6 4.1 3 2 0 3 3 2 1 AAA ATPase domain HTH_23 PF13384.6 ABK73468.1 - 3.9e-05 23.3 0.4 0.00031 20.4 0.0 2.8 2 0 0 2 2 2 1 Homeodomain-like domain AAA_22 PF13401.6 ABK73468.1 - 0.00048 20.4 0.0 0.0041 17.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain HTH_28 PF13518.6 ABK73468.1 - 0.0029 17.7 0.1 0.08 13.1 0.0 3.5 1 1 1 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 ABK73468.1 - 0.003 17.2 0.0 0.014 15.0 0.0 2.3 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.6 ABK73468.1 - 0.004 16.5 0.7 0.04 13.3 0.1 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4 PF04545.16 ABK73468.1 - 0.0075 15.8 0.0 0.029 13.9 0.0 2.1 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 ABK73468.1 - 0.01 15.6 0.1 0.11 12.2 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain AAA_5 PF07728.14 ABK73468.1 - 0.021 14.8 0.1 3.7 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 ABK73468.1 - 0.14 12.1 0.0 0.56 10.1 0.0 2.1 1 1 0 1 1 1 0 NACHT domain HTH_24 PF13412.6 ABK73468.1 - 0.14 11.7 0.0 0.37 10.4 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding SGL PF08450.12 ABK73469.1 - 2.7e-57 194.2 0.0 3.1e-57 194.0 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 ABK73469.1 - 0.032 14.4 0.0 0.083 13.1 0.0 1.7 1 0 0 1 1 1 0 Arylesterase Lactonase PF10282.9 ABK73469.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller PQQ_3 PF13570.6 ABK73469.1 - 0.6 10.7 6.3 2.7 8.6 0.1 3.7 3 1 0 3 3 3 0 PQQ-like domain SNARE_assoc PF09335.11 ABK73471.1 - 8e-23 81.2 6.6 8e-23 81.2 6.6 2.0 2 0 0 2 2 2 1 SNARE associated Golgi protein Tad PF13400.6 ABK73471.1 - 0.012 15.9 1.2 0.012 15.9 1.2 4.8 4 1 1 5 5 5 0 Putative Flp pilus-assembly TadE/G-like AICARFT_IMPCHas PF01808.18 ABK73472.1 - 4.3e-114 380.9 0.0 5.9e-114 380.5 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 ABK73472.1 - 2.2e-24 85.4 0.0 3.9e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 MGS-like domain MFS_1 PF07690.16 ABK73473.1 - 1.6e-15 56.9 94.6 5.6e-13 48.5 56.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ABK73473.1 - 0.0001 21.0 11.4 0.0001 21.0 11.4 2.3 1 1 1 2 2 2 1 MFS/sugar transport protein NAD_binding_10 PF13460.6 ABK73474.1 - 2.7e-11 43.7 7.7 2.7e-09 37.2 7.7 2.3 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ABK73474.1 - 1.1e-07 31.7 2.6 1.5e-05 24.7 2.6 2.1 1 1 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 ABK73474.1 - 3.3e-06 26.4 0.3 0.0032 16.6 0.2 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain Epimerase PF01370.21 ABK73474.1 - 2.9e-05 23.6 1.4 0.00058 19.4 1.4 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ApbA PF02558.16 ABK73474.1 - 0.0031 17.2 0.2 0.0047 16.6 0.2 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 ABK73474.1 - 0.021 15.1 2.0 6.2 7.1 1.0 2.3 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 ABK73474.1 - 0.053 12.5 1.8 1.3 8.0 1.9 2.2 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 ABK73474.1 - 0.16 12.1 0.8 0.41 10.8 0.8 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Pyr_redox PF00070.27 ABK73474.1 - 0.2 12.2 1.7 0.4 11.3 1.7 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 ABK73474.1 - 0.84 9.1 3.8 2.2 7.7 2.2 2.0 2 0 0 2 2 2 0 short chain dehydrogenase 4PPT_N PF17837.1 ABK73476.1 - 5.8e-26 90.4 0.0 1.2e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase N-terminal domain ACPS PF01648.20 ABK73476.1 - 6e-12 45.7 0.0 2.8e-11 43.5 0.0 1.8 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily CorA PF01544.18 ABK73477.1 - 3.1e-70 236.8 0.0 3.6e-70 236.6 0.0 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ABC2_membrane_2 PF12679.7 ABK73477.1 - 0.076 12.3 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Acyl_transf_3 PF01757.22 ABK73478.1 - 3.1e-22 79.1 35.2 6.3e-22 78.1 35.2 1.5 1 1 0 1 1 1 1 Acyltransferase family DUF5592 PF17332.2 ABK73478.1 - 0.015 15.8 0.4 0.044 14.4 0.4 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5592) UPF0182 PF03699.13 ABK73478.1 - 0.094 10.8 3.4 0.19 9.8 3.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Bacteriocin_IIc PF10439.9 ABK73478.1 - 1.8 8.8 5.6 0.77 9.9 0.1 2.8 3 0 0 3 3 3 0 Bacteriocin class II with double-glycine leader peptide YfhO PF09586.10 ABK73478.1 - 2.7 6.1 7.6 4.8 5.3 7.6 1.3 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Glutaminase PF04960.15 ABK73479.1 - 4.9e-82 275.3 0.0 5.5e-82 275.2 0.0 1.0 1 0 0 1 1 1 1 Glutaminase HTH_Tnp_1 PF01527.20 ABK73480.1 - 0.00094 19.5 0.8 0.0022 18.3 0.8 1.6 1 1 0 1 1 1 1 Transposase DUF4407 PF14362.6 ABK73480.1 - 0.039 13.3 0.9 0.045 13.1 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Paramyx_P_V_C PF03210.13 ABK73480.1 - 0.096 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal Ribosomal_L11 PF00298.19 ABK73480.1 - 0.11 13.1 0.2 0.16 12.5 0.2 1.3 1 0 0 1 1 1 0 Ribosomal protein L11, RNA binding domain SlyX PF04102.12 ABK73480.1 - 0.11 13.1 1.1 0.28 11.8 1.1 1.7 1 1 0 1 1 1 0 SlyX DUF1192 PF06698.11 ABK73480.1 - 1.7 8.7 5.2 1.6 8.8 3.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) BPD_transp_2 PF02653.16 ABK73482.1 - 9.1e-36 123.4 45.7 1e-35 123.2 45.7 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component BPD_transp_1 PF00528.22 ABK73483.1 - 7.6e-40 136.6 11.0 7.6e-40 136.6 11.0 2.1 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF3333 PF11812.8 ABK73483.1 - 0.032 14.5 0.4 0.081 13.1 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3333) FAD_binding_3 PF01494.19 ABK73484.1 - 2.7e-15 56.5 0.1 4.8e-15 55.7 0.1 1.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ABK73484.1 - 0.0018 18.5 0.1 0.0063 16.7 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ABK73484.1 - 0.0021 17.7 0.8 0.07 12.7 0.1 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ABK73484.1 - 0.0068 15.7 0.4 0.077 12.2 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 ABK73484.1 - 0.017 14.8 0.1 0.03 13.9 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 ABK73484.1 - 0.049 14.2 0.1 0.32 11.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ABK73484.1 - 0.095 11.7 0.0 0.21 10.6 0.0 1.6 1 1 0 1 1 1 0 Lycopene cyclase protein NanE PF04131.14 ABK73484.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Ribosom_S12_S23 PF00164.25 ABK73485.1 - 2.2e-42 143.2 3.1 2.6e-42 143.0 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 UPF0193 PF05250.11 ABK73486.1 - 0.11 12.3 0.1 0.16 11.7 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0193) MSP1_C PF07462.11 ABK73486.1 - 0.15 10.7 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF2599 PF10783.9 ABK73487.1 - 7.9e-39 132.2 0.3 9.8e-39 131.9 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2599) MTHFR PF02219.17 ABK73488.1 - 4e-08 32.9 0.0 6.4e-08 32.3 0.0 1.3 1 1 0 1 1 1 1 Methylenetetrahydrofolate reductase BPD_transp_1 PF00528.22 ABK73489.1 - 5.4e-14 52.3 21.4 2.2e-12 47.1 17.8 2.0 1 1 1 2 2 2 2 Binding-protein-dependent transport system inner membrane component DUF4134 PF13572.6 ABK73489.1 - 0.009 16.3 0.0 0.028 14.7 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4134) stn_TNFRSF12A PF12191.8 ABK73489.1 - 0.069 13.4 0.6 0.19 11.9 0.3 1.9 1 1 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain CBP_BcsF PF11120.8 ABK73489.1 - 0.41 10.8 0.1 0.41 10.8 0.1 3.1 3 0 0 3 3 3 0 Cellulose biosynthesis protein BcsF Neurensin PF14927.6 ABK73489.1 - 0.53 10.0 0.0 0.53 10.0 0.0 2.7 3 2 0 3 3 3 0 Neurensin DUF973 PF06157.11 ABK73489.1 - 1.6 7.8 6.2 0.28 10.2 1.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF973) Ribosomal_L29 PF00831.23 ABK73490.1 - 5.8e-25 87.0 4.1 6.6e-25 86.8 4.1 1.0 1 0 0 1 1 1 1 Ribosomal L29 protein SpoVIF PF14069.6 ABK73490.1 - 0.069 12.9 0.1 0.092 12.5 0.1 1.1 1 0 0 1 1 1 0 Stage VI sporulation protein F LEM PF03020.15 ABK73490.1 - 0.22 11.1 2.7 0.4 10.3 1.8 2.0 2 0 0 2 2 2 0 LEM domain MaoC_dehydrat_N PF13452.6 ABK73491.1 - 4.3e-25 88.4 0.1 5.5e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase Lipase_GDSL_2 PF13472.6 ABK73492.1 - 1.9e-18 67.5 0.0 2.8e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ABK73492.1 - 3.5e-05 23.9 0.0 0.00017 21.6 0.0 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase HCV_NS4a PF01006.20 ABK73492.1 - 0.12 12.2 2.6 0.24 11.2 0.4 2.6 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4a Polysacc_synt PF01943.17 ABK73493.1 - 7.1e-16 58.4 10.8 7.1e-16 58.4 10.8 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein DUF1072 PF06380.11 ABK73493.1 - 2.1 8.3 6.3 0.41 10.5 0.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) CMD PF02627.20 ABK73494.1 - 3.4e-17 62.3 2.3 1.4e-16 60.3 0.5 2.0 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family CMD PF02627.20 ABK73495.1 - 4.2e-20 71.6 0.0 4.9e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Folate_carrier PF01770.18 ABK73495.1 - 0.25 10.0 0.0 0.32 9.7 0.0 1.0 1 0 0 1 1 1 0 Reduced folate carrier CoA_transf_3 PF02515.17 ABK73496.1 - 3.6e-120 401.5 0.2 4.1e-120 401.3 0.2 1.0 1 0 0 1 1 1 1 CoA-transferase family III MaoC_dehydratas PF01575.19 ABK73497.1 - 5.7e-05 22.7 0.0 6.9e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 ABK73497.1 - 0.091 12.9 0.0 6.4 6.9 0.0 2.1 2 0 0 2 2 2 0 N-terminal half of MaoC dehydratase bPH_2 PF03703.14 ABK73498.1 - 9.3e-19 67.4 0.1 1.3e-18 67.0 0.1 1.2 1 0 0 1 1 1 1 Bacterial PH domain bPH_3 PF14470.6 ABK73498.1 - 0.023 15.1 0.0 0.033 14.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial PH domain adh_short PF00106.25 ABK73499.1 - 4.2e-48 163.4 0.3 5.2e-48 163.1 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK73499.1 - 9.8e-39 133.3 2.0 1.3e-38 132.9 2.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK73499.1 - 7.2e-14 52.1 0.3 1.3e-13 51.2 0.3 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ABK73499.1 - 1.2e-06 28.6 3.2 1.4e-06 28.3 2.6 1.5 1 1 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 ABK73499.1 - 0.00079 18.9 0.0 0.0011 18.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 ABK73499.1 - 0.046 13.2 0.1 0.15 11.5 0.1 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ABK73499.1 - 0.067 12.3 0.3 0.1 11.7 0.3 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Glyco_transf_4 PF13439.6 ABK73499.1 - 0.068 13.2 0.4 1.1 9.3 0.1 2.3 2 1 0 2 2 2 0 Glycosyltransferase Family 4 DctM PF06808.12 ABK73499.1 - 0.21 10.4 0.7 0.32 9.8 0.7 1.2 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporter, DctM component adh_short_C2 PF13561.6 ABK73501.1 - 1.5e-60 204.7 0.6 2e-60 204.3 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK73501.1 - 1.7e-49 167.9 0.2 2.2e-49 167.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK73501.1 - 2.1e-11 44.1 1.4 3.7e-10 40.0 1.4 2.0 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ABK73501.1 - 0.00044 20.2 0.3 0.0016 18.4 0.1 2.0 2 1 1 3 3 3 1 NAD(P)H-binding Epimerase PF01370.21 ABK73501.1 - 0.0047 16.4 0.1 0.0096 15.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family LytR_C PF13399.6 ABK73501.1 - 0.023 15.7 1.0 2.9 8.9 0.1 2.6 2 1 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator CbiX PF01903.17 ABK73502.1 - 7e-25 87.4 0.3 2e-14 53.8 0.1 2.6 2 1 0 2 2 2 2 CbiX CbiK PF06180.11 ABK73502.1 - 0.044 13.1 0.0 0.45 9.8 0.1 1.9 2 0 0 2 2 2 0 Cobalt chelatase (CbiK) KdpA PF03814.15 ABK73503.1 - 1.9e-225 749.2 26.9 2.2e-225 749.0 26.9 1.0 1 0 0 1 1 1 1 Potassium-transporting ATPase A subunit Gln-synt_C PF00120.24 ABK73505.1 - 4.7e-86 288.9 0.0 8.7e-86 288.0 0.0 1.4 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 ABK73505.1 - 7.2e-05 22.5 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DUF3303 PF11746.8 ABK73506.1 - 4.1e-19 68.6 0.2 4.7e-19 68.5 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3303) Glyoxalase PF00903.25 ABK73507.1 - 7.8e-16 58.4 0.4 1e-15 58.0 0.4 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ABK73507.1 - 5.8e-11 42.6 0.1 9.7e-11 41.9 0.1 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ABK73507.1 - 4.3e-08 33.9 0.3 6.6e-08 33.3 0.3 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 ABK73507.1 - 0.0046 16.9 0.0 0.037 13.9 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 ABK73507.1 - 0.005 17.0 0.2 0.024 14.7 0.2 2.0 1 1 0 1 1 1 1 Glyoxalase-like domain H2O2_YaaD PF03883.14 ABK73508.1 - 2.9e-37 128.4 0.0 3.4e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 Peroxide stress protein YaaA Rhodanese PF00581.20 ABK73508.1 - 0.02 15.4 0.0 0.037 14.5 0.0 1.4 1 0 0 1 1 1 0 Rhodanese-like domain GSHPx PF00255.19 ABK73509.1 - 2.6e-35 120.3 0.0 3.2e-35 120.0 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 ABK73509.1 - 9.1e-05 22.4 0.0 0.00016 21.6 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ABK73509.1 - 0.00012 21.8 0.0 0.00017 21.4 0.0 1.5 1 1 0 1 1 1 1 Redoxin PadR PF03551.14 ABK73510.1 - 7.6e-22 77.1 0.1 1.4e-21 76.2 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family Vir_act_alpha_C PF10400.9 ABK73510.1 - 0.0001 22.9 0.6 0.00022 21.8 0.6 1.5 1 0 0 1 1 1 1 Virulence activator alpha C-term AphA_like PF14557.6 ABK73510.1 - 0.0033 17.2 0.0 0.0045 16.7 0.0 1.1 1 0 0 1 1 1 1 Putative AphA-like transcriptional regulator HxlR PF01638.17 ABK73510.1 - 0.059 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 HxlR-like helix-turn-helix HTH_34 PF13601.6 ABK73510.1 - 0.061 13.5 0.0 0.6 10.3 0.0 2.3 2 0 0 2 2 2 0 Winged helix DNA-binding domain zf-C2H2_9 PF16293.5 ABK73510.1 - 0.17 11.8 0.0 0.66 9.9 0.0 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) F_bP_aldolase PF01116.20 ABK73511.1 - 1.5e-68 231.3 0.0 1.6e-68 231.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II ZNRF_3_ecto PF18212.1 ABK73511.1 - 0.18 11.8 2.2 14 5.7 0.1 2.8 2 1 1 3 3 3 0 ZNRF-3 Ectodomain PHO4 PF01384.20 ABK73512.1 - 5.9e-78 262.3 32.6 2e-77 260.5 32.6 1.7 1 1 0 1 1 1 1 Phosphate transporter family OPA3 PF07047.12 ABK73512.1 - 0.019 14.7 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) TMEM89 PF15098.6 ABK73512.1 - 0.064 13.4 0.3 1.1 9.4 0.0 2.5 3 0 0 3 3 3 0 TMEM89 protein family DUF4131 PF13567.6 ABK73512.1 - 0.23 11.1 0.0 0.23 11.1 0.0 4.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) Ferritin PF00210.24 ABK73513.1 - 0.00063 19.7 0.2 0.0015 18.5 0.1 1.7 2 0 0 2 2 2 1 Ferritin-like domain DUF892 PF05974.12 ABK73513.1 - 0.018 15.0 0.6 0.057 13.4 0.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF892) DUF2383 PF09537.10 ABK73513.1 - 0.029 14.7 0.1 0.25 11.7 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF2383) SnoaL_2 PF12680.7 ABK73514.1 - 6.3e-11 42.8 1.1 1.2e-10 42.0 1.1 1.5 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 ABK73514.1 - 1.3e-05 25.0 0.3 2.2e-05 24.3 0.3 1.5 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_4 PF13577.6 ABK73514.1 - 0.018 15.1 0.6 0.032 14.3 0.6 1.5 1 0 0 1 1 1 0 SnoaL-like domain Prok-JAB PF14464.6 ABK73517.1 - 5.1e-27 94.0 0.7 5.8e-27 93.8 0.7 1.0 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain JAB PF01398.21 ABK73517.1 - 0.063 13.3 0.0 0.16 12.0 0.0 1.6 1 1 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease SpoIIP PF07454.11 ABK73517.1 - 0.1 12.1 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) ROK PF00480.20 ABK73518.1 - 5.1e-19 68.8 5.4 3.4e-16 59.6 2.7 2.5 1 1 1 2 2 2 2 ROK family DDE_Tnp_ISL3 PF01610.17 ABK73519.1 - 1.6e-64 217.9 0.0 2.1e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Transposase zf-ISL3 PF14690.6 ABK73519.1 - 1.1e-09 38.8 4.6 1.8e-09 38.1 2.5 2.5 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HTH_Tnp_ISL3 PF13542.6 ABK73519.1 - 2.4e-08 33.2 1.6 7e-08 31.8 1.6 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 SNARE_assoc PF09335.11 ABK73520.1 - 1.5e-23 83.6 5.4 1.5e-23 83.6 5.4 2.5 2 1 1 3 3 3 1 SNARE associated Golgi protein FxsA PF04186.13 ABK73520.1 - 0.57 10.3 12.9 1.6 8.9 0.8 3.5 1 1 1 3 3 3 0 FxsA cytoplasmic membrane protein adh_short PF00106.25 ABK73521.1 - 2.4e-38 131.6 0.0 3e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK73521.1 - 1.4e-24 87.0 0.1 1.9e-24 86.5 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 ABK73521.1 - 1.9e-07 31.1 0.6 3.1e-07 30.5 0.6 1.5 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 ABK73521.1 - 1.3e-06 28.4 0.2 1.5e-05 25.0 0.2 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK73521.1 - 2.9e-06 26.9 0.1 1.4e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ABK73521.1 - 0.00065 18.9 0.0 0.0014 17.8 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain DUF1776 PF08643.10 ABK73521.1 - 0.0082 15.5 0.0 0.021 14.2 0.0 1.6 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Bac_DNA_binding PF00216.21 ABK73522.1 - 3.3e-26 91.3 0.3 3.3e-26 91.3 0.3 2.9 2 1 0 2 2 2 1 Bacterial DNA-binding protein HU-HIG PF18291.1 ABK73522.1 - 0.00096 19.2 0.0 0.0019 18.3 0.0 1.5 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_euk_2 PF18289.1 ABK73522.1 - 0.0079 16.3 0.1 0.013 15.7 0.1 1.3 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 HU-CCDC81_bac_2 PF18175.1 ABK73522.1 - 0.0085 15.9 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 HU-CCDC81_euk_1 PF14908.6 ABK73522.1 - 0.032 14.4 0.0 0.053 13.7 0.0 1.3 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 1 Oxidored_FMN PF00724.20 ABK73523.1 - 8.6e-70 235.7 0.0 1.1e-69 235.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 ABK73523.1 - 1.5e-07 30.8 1.0 1.7e-07 30.6 0.1 1.6 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 ABK73523.1 - 0.038 13.4 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein TetR_N PF00440.23 ABK73524.1 - 2.5e-10 40.0 0.3 7.7e-10 38.4 0.2 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_8 PF14278.6 ABK73524.1 - 3.7e-05 23.8 0.0 5.2e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator C-terminal region PAP2 PF01569.21 ABK73525.1 - 1.6e-16 60.3 11.2 1.6e-16 60.3 11.2 3.0 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 ABK73525.1 - 0.003 17.3 18.3 0.003 17.3 18.3 1.8 2 1 0 2 2 2 1 PAP2 superfamily NrsF PF06532.11 ABK73525.1 - 0.73 9.5 26.2 0.28 10.9 18.7 2.1 2 0 0 2 2 2 0 Negative regulator of sigma F XdhC_C PF13478.6 ABK73526.1 - 3e-21 76.2 0.4 5.7e-21 75.3 0.4 1.5 1 0 0 1 1 1 1 XdhC Rossmann domain XdhC_CoxI PF02625.16 ABK73526.1 - 2.3e-13 50.1 0.4 2.3e-13 50.1 0.4 2.6 4 0 0 4 4 4 1 XdhC and CoxI family PrsW-protease PF13367.6 ABK73527.1 - 8.9e-44 149.3 12.2 1.8e-43 148.3 12.2 1.5 1 0 0 1 1 1 1 PrsW family intramembrane metalloprotease MTES_1575 PF18741.1 ABK73528.1 - 1.9e-07 31.2 0.3 2.7e-07 30.7 0.3 1.3 1 0 0 1 1 1 1 REase_MTES_1575 DUF559 PF04480.12 ABK73528.1 - 3.6e-05 23.6 0.0 5.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF559) DAP_epimerase PF01678.19 ABK73529.1 - 1.2e-57 193.4 1.9 2.3e-36 124.6 0.1 2.1 2 0 0 2 2 2 2 Diaminopimelate epimerase DUF4307 PF14155.6 ABK73529.1 - 0.0094 15.8 0.9 0.031 14.1 0.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4307) Abhydrolase_6 PF12697.7 ABK73531.1 - 1.6e-14 55.0 11.1 2.4e-14 54.5 11.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK73531.1 - 1.3e-09 37.7 0.2 1.3e-08 34.4 0.2 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ABK73531.1 - 1.6e-08 34.5 0.1 2.1e-07 30.9 0.1 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.20 ABK73531.1 - 0.079 13.1 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF1057 PF06342.12 ABK73531.1 - 0.18 10.8 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) DapB_N PF01113.20 ABK73532.1 - 2.1e-06 27.9 0.0 4.7e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Ferrochelatase PF00762.19 ABK73533.1 - 5.2e-99 331.3 0.0 6.1e-99 331.1 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 ABK73533.1 - 0.011 16.0 0.0 0.55 10.6 0.0 2.5 2 0 0 2 2 2 0 CbiX SAICAR_synt PF01259.18 ABK73534.1 - 3.3e-98 328.3 0.0 3.9e-98 328.1 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase R3H PF01424.22 ABK73535.1 - 2.8e-15 56.0 0.0 6.7e-15 54.8 0.0 1.7 2 0 0 2 2 2 1 R3H domain KH_4 PF13083.6 ABK73535.1 - 2.1e-08 33.9 0.1 3.8e-08 33.1 0.1 1.3 1 0 0 1 1 1 1 KH domain Abhydrolase_6 PF12697.7 ABK73536.1 - 2.6e-20 74.0 18.0 3e-20 73.8 18.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ABK73536.1 - 2.6e-10 40.4 0.1 3.7e-10 39.9 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ABK73536.1 - 7.8e-10 38.4 0.1 1.1e-09 38.0 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 ABK73536.1 - 0.036 13.6 0.0 0.27 10.7 0.0 1.9 1 1 0 1 1 1 0 Putative serine esterase (DUF676) UvrD-helicase PF00580.21 ABK73537.1 - 1.5e-74 251.4 0.0 1.6e-73 248.0 0.0 2.1 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 ABK73537.1 - 9.2e-69 232.4 0.0 1.3e-68 231.9 0.0 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 ABK73537.1 - 1.9e-33 115.8 0.0 3.9e-33 114.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 ABK73537.1 - 1.8e-11 43.6 0.0 5e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 ABK73537.1 - 9.1e-07 28.8 2.7 2.4e-05 24.2 0.2 2.4 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 ABK73537.1 - 0.0071 16.2 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ABK73537.1 - 0.0086 16.3 0.1 5.2 7.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain CarD_CdnL_TRCF PF02559.16 ABK73537.1 - 0.077 13.7 0.1 0.31 11.8 0.0 2.1 2 0 0 2 2 2 0 CarD-like/TRCF domain Terminase_6 PF03237.15 ABK73537.1 - 0.084 12.5 0.0 0.31 10.6 0.0 2.0 1 0 0 1 1 1 0 Terminase-like family DEAD PF00270.29 ABK73537.1 - 0.1 12.3 0.2 0.29 10.9 0.0 1.8 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_16 PF13191.6 ABK73537.1 - 0.12 12.7 3.6 0.14 12.5 0.7 2.6 2 1 0 2 2 2 0 AAA ATPase domain Viral_helicase1 PF01443.18 ABK73537.1 - 0.16 11.7 0.1 13 5.4 0.0 3.1 3 2 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Ribonuc_L-PSP PF01042.21 ABK73538.1 - 4.3e-20 71.9 0.0 5.3e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP MFS_1 PF07690.16 ABK73539.1 - 3.9e-13 49.1 24.5 6.1e-13 48.4 24.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MlaD PF02470.20 ABK73542.1 - 6.3e-15 55.2 0.1 1.3e-14 54.2 0.1 1.6 1 0 0 1 1 1 1 MlaD protein Mce4_CUP1 PF11887.8 ABK73542.1 - 7.4e-10 38.7 0.3 1.1e-09 38.1 0.3 1.2 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative DUF5345 PF17280.2 ABK73542.1 - 0.31 11.0 1.4 0.63 10.1 1.4 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5345) Response_reg PF00072.24 ABK73543.1 - 1.3e-23 83.3 0.0 1.8e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain LytTR PF04397.15 ABK73543.1 - 1e-20 73.7 0.0 1.6e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 LytTr DNA-binding domain Fn_bind PF02986.14 ABK73544.1 - 4.2 7.2 6.0 11 5.9 6.0 1.7 1 0 0 1 1 1 0 Fibronectin binding repeat Med11 PF10280.9 ABK73544.1 - 7.9 6.9 11.1 67 3.9 11.1 2.1 1 1 0 1 1 1 0 Mediator complex protein DivIVA PF05103.13 ABK73545.1 - 0.0012 18.9 0.0 0.0014 18.8 0.0 1.1 1 0 0 1 1 1 1 DivIVA protein RXLR PF16810.5 ABK73545.1 - 0.059 13.8 0.0 0.075 13.5 0.0 1.2 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity DDE_Tnp_ISL3 PF01610.17 ABK73547.1 - 1.6e-64 217.9 0.0 2.1e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Transposase zf-ISL3 PF14690.6 ABK73547.1 - 1.1e-09 38.8 4.6 1.8e-09 38.1 2.5 2.5 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HTH_Tnp_ISL3 PF13542.6 ABK73547.1 - 2.4e-08 33.2 1.6 7e-08 31.8 1.6 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 AA_kinase PF00696.28 ABK73548.1 - 1.6e-44 152.3 2.0 1.9e-44 152.1 2.0 1.0 1 0 0 1 1 1 1 Amino acid kinase family NMT1_2 PF13379.6 ABK73549.1 - 1.4e-42 146.2 1.5 2e-42 145.7 1.5 1.2 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 ABK73549.1 - 0.023 14.7 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 NMT1/THI5 like BPD_transp_1 PF00528.22 ABK73550.1 - 8.3e-12 45.2 16.0 8.3e-12 45.2 16.0 3.0 1 1 2 3 3 3 1 Binding-protein-dependent transport system inner membrane component FeoB_associated PF12669.7 ABK73550.1 - 0.52 10.8 4.3 30 5.1 0.0 3.1 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein tRNA-synt_2b PF00587.25 ABK73551.1 - 8.5e-35 120.3 0.0 1.5e-34 119.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 ABK73551.1 - 2.5e-16 59.6 0.0 5.9e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 ABK73551.1 - 3.2e-12 46.3 0.0 6.2e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain SLATT_1 PF18181.1 ABK73552.1 - 0.042 13.8 2.1 0.062 13.2 2.1 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 DUF412 PF04217.13 ABK73552.1 - 0.069 13.0 0.5 0.088 12.7 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF412 POTRA_1 PF08478.10 ABK73553.1 - 3.7e-16 59.2 0.1 8.9e-16 57.9 0.1 1.6 2 0 0 2 2 2 1 POTRA domain, FtsQ-type FtsQ PF03799.15 ABK73553.1 - 1.7e-06 28.8 0.0 3.4e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Cell division protein FtsQ DotU PF09850.9 ABK73553.1 - 0.055 13.2 0.7 0.094 12.4 0.7 1.2 1 0 0 1 1 1 0 Type VI secretion system protein DotU DUF3619 PF12279.8 ABK73553.1 - 1.6 9.1 5.8 1.5 9.2 2.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) TT_ORF1 PF02956.14 ABK73553.1 - 3 6.4 3.9 4.2 5.9 3.9 1.1 1 0 0 1 1 1 0 TT viral orf 1 PhageMin_Tail PF10145.9 ABK73554.1 - 1.3e-15 57.8 1.3 1.3e-15 57.8 1.3 4.8 4 1 1 5 5 5 1 Phage-related minor tail protein YscO PF07321.12 ABK73554.1 - 4.3 7.3 23.0 0.084 12.8 4.0 2.8 2 0 0 2 2 2 0 Type III secretion protein YscO Cu_amine_oxid PF01179.20 ABK73555.1 - 1.9e-165 550.7 0.0 2.3e-165 550.5 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 ABK73555.1 - 9e-17 61.3 0.0 2.1e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 ABK73555.1 - 4.9e-09 36.3 0.0 8.6e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain ABC2_membrane PF01061.24 ABK73556.1 - 3.2e-23 82.3 20.2 4.6e-23 81.7 20.2 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 ABK73556.1 - 5.5e-13 48.8 18.5 5.5e-13 48.8 18.5 1.9 1 1 1 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 ABK73556.1 - 0.00055 19.3 13.3 0.00071 18.9 13.3 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 ABK73556.1 - 0.0035 17.3 8.7 0.0035 17.3 8.7 2.7 2 1 1 4 4 4 1 ABC-2 family transporter protein Patatin PF01734.22 ABK73556.1 - 0.061 13.5 0.2 0.079 13.1 0.2 1.3 1 0 0 1 1 1 0 Patatin-like phospholipase DUF4011 PF13195.6 ABK73558.1 - 1.9e-31 109.2 0.0 3.7e-31 108.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4011) AAA_12 PF13087.6 ABK73558.1 - 2.9e-19 69.5 0.0 5.5e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ABK73558.1 - 1.1e-16 61.4 0.0 1.5e-08 34.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain HEPN_Swt1 PF18731.1 ABK73558.1 - 1.8e-14 54.1 0.0 4.9e-14 52.7 0.0 1.8 1 0 0 1 1 1 1 Swt1-like HEPN MTES_1575 PF18741.1 ABK73558.1 - 5.8e-13 48.8 0.1 2.4e-12 46.8 0.1 2.1 2 0 0 2 2 2 1 REase_MTES_1575 DUF3320 PF11784.8 ABK73558.1 - 3e-11 43.1 0.2 1e-10 41.4 0.2 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3320) AAA_30 PF13604.6 ABK73558.1 - 1.3e-10 41.3 2.0 3.5e-07 30.1 0.2 3.4 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 ABK73558.1 - 2.9e-08 34.2 0.0 7.3e-06 26.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 ABK73558.1 - 0.00023 21.0 0.0 0.25 11.0 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 ABK73558.1 - 0.0021 18.5 1.0 0.0021 18.5 1.0 4.0 5 1 0 5 5 4 1 AAA ATPase domain DUF2075 PF09848.9 ABK73558.1 - 0.0022 17.3 0.2 0.21 10.8 0.0 3.1 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 ABK73558.1 - 0.013 15.3 0.3 0.069 13.0 0.1 2.3 2 0 0 2 2 2 0 Helicase ACP PF06857.11 ABK73558.1 - 0.02 15.1 0.2 0.16 12.2 0.1 2.5 2 0 0 2 2 2 0 Malonate decarboxylase delta subunit (MdcD) IstB_IS21 PF01695.17 ABK73558.1 - 0.021 14.6 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein HTH_psq PF05225.16 ABK73558.1 - 0.031 14.0 0.0 0.49 10.2 0.0 2.7 2 0 0 2 2 2 0 helix-turn-helix, Psq domain AAA_18 PF13238.6 ABK73558.1 - 0.039 14.5 0.0 1.7 9.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain Transglut_core PF01841.19 ABK73558.1 - 0.051 14.0 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 Transglutaminase-like superfamily UvrD-helicase PF00580.21 ABK73558.1 - 0.059 12.9 0.2 0.13 11.8 0.2 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_28 PF13521.6 ABK73558.1 - 0.093 13.0 0.0 0.49 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 ABK73558.1 - 0.11 11.3 0.0 0.27 10.1 0.0 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_33 PF13671.6 ABK73558.1 - 0.12 12.6 0.1 1.8 8.7 0.0 3.0 4 0 0 4 4 3 0 AAA domain AAA_5 PF07728.14 ABK73558.1 - 0.16 11.9 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ResIII PF04851.15 ABK73558.1 - 0.2 11.6 0.0 0.46 10.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Semialdhyde_dhC PF02774.18 ABK73560.1 - 4.4e-25 88.8 1.0 6.8e-25 88.2 0.1 1.8 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 ABK73560.1 - 1.3e-21 77.2 0.0 2.8e-21 76.2 0.0 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain AAA_16 PF13191.6 ABK73560.1 - 0.082 13.3 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AMP-binding PF00501.28 ABK73561.1 - 8.2e-85 284.9 0.0 1.3e-84 284.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK73561.1 - 3.6e-18 66.3 3.6 8.5e-18 65.1 3.6 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 ABK73561.1 - 0.012 15.9 0.1 0.019 15.2 0.1 1.3 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK73563.1 - 2.1e-24 86.3 0.2 2.3e-23 83.0 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 ABK73563.1 - 1.5e-21 77.2 0.2 2.5e-21 76.5 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK73563.1 - 3.1e-20 72.2 0.0 7.1e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain PhoU PF01895.19 ABK73564.1 - 1.9e-23 82.7 4.7 8.4e-13 48.6 0.8 2.1 2 0 0 2 2 2 2 PhoU domain Repressor_Mnt PF11423.8 ABK73564.1 - 0.089 12.6 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 Regulatory protein Mnt Bac_luciferase PF00296.20 ABK73565.1 - 3.3e-28 99.0 4.3 4.9e-28 98.5 4.3 1.3 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF1561 PF07598.11 ABK73565.1 - 0.023 12.9 0.0 0.032 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1561) HERV-K_REC PF15695.5 ABK73565.1 - 0.15 12.1 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Rec (regulator of expression encoded by corf) of HERV-K-113 Glycos_transf_2 PF00535.26 ABK73566.1 - 1e-10 41.7 0.0 3.2e-10 40.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ABK73566.1 - 2.2e-05 24.4 0.0 3.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Aminotran_1_2 PF00155.21 ABK73567.1 - 7.7e-49 166.8 0.0 8.7e-49 166.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 ABK73567.1 - 2.3e-08 33.7 0.0 3.3e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 ABK73567.1 - 0.00013 21.1 0.0 0.00022 20.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 ABK73567.1 - 0.0021 17.4 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 ABK73567.1 - 0.007 14.9 0.0 0.011 14.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.13 ABK73567.1 - 0.1 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Allinase FUSC_2 PF13515.6 ABK73568.1 - 9.2e-20 71.1 19.4 9.2e-20 71.1 19.4 3.2 2 1 0 2 2 2 1 Fusaric acid resistance protein-like CBAH PF02275.18 ABK73569.1 - 6.7e-58 196.8 0.0 3.6e-57 194.4 0.0 1.8 1 1 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family AAT PF03417.16 ABK73569.1 - 3.4e-09 36.7 0.0 4.7e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase EcKinase PF02958.20 ABK73570.1 - 4.4e-14 52.5 0.0 7.2e-09 35.4 0.0 2.1 2 0 0 2 2 2 2 Ecdysteroid kinase APH PF01636.23 ABK73570.1 - 9.1e-12 45.4 9.7 1.1e-11 45.2 8.6 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 ABK73570.1 - 4e-06 25.9 0.0 5.7e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Tir_receptor_C PF07489.11 ABK73571.1 - 0.041 13.8 0.2 0.052 13.5 0.2 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus CAP_N PF01213.19 ABK73571.1 - 0.76 9.2 5.5 0.99 8.8 5.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal ABC_membrane_2 PF06472.15 ABK73572.1 - 5.1e-79 265.4 0.8 7e-79 265.0 0.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 SbmA_BacA PF05992.12 ABK73572.1 - 1.1e-26 94.0 3.1 2.8e-26 92.7 3.1 1.6 1 1 0 1 1 1 1 SbmA/BacA-like family ABC_tran PF00005.27 ABK73572.1 - 2e-16 60.8 0.0 4.8e-16 59.5 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 ABK73572.1 - 6.3e-07 29.9 0.0 2.3e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 ABK73572.1 - 7.1e-07 29.3 0.9 1.1e-05 25.4 0.9 2.2 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 ABK73572.1 - 0.00026 21.3 0.0 0.00059 20.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ABK73572.1 - 0.0004 20.2 0.1 0.0011 18.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 ABK73572.1 - 0.0029 18.0 0.0 0.013 15.9 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 ABK73572.1 - 0.0029 17.3 0.7 0.0061 16.3 0.1 1.8 2 0 0 2 2 1 1 P-loop containing region of AAA domain AAA_5 PF07728.14 ABK73572.1 - 0.0078 16.2 0.1 0.042 13.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 ABK73572.1 - 0.0082 15.7 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 ABK73572.1 - 0.012 15.7 0.1 0.025 14.6 0.1 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_28 PF13521.6 ABK73572.1 - 0.025 14.9 0.1 0.049 13.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ABK73572.1 - 0.025 15.1 0.0 0.044 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 ABK73572.1 - 0.046 12.8 0.0 0.076 12.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_21 PF13304.6 ABK73572.1 - 0.049 13.4 0.0 0.14 12.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ABK73572.1 - 0.074 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase FtsK_SpoIIIE PF01580.18 ABK73572.1 - 0.084 12.2 0.0 0.99 8.7 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_24 PF13479.6 ABK73572.1 - 0.11 12.3 0.2 0.2 11.3 0.2 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 ABK73572.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_13 PF13166.6 ABK73572.1 - 0.12 11.1 0.0 5.9 5.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 ABK73572.1 - 0.13 12.7 0.0 0.22 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 ABK73572.1 - 0.15 11.7 0.2 0.23 11.0 0.2 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 ABK73572.1 - 0.16 12.2 0.1 0.35 11.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 ABK73572.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_ATPase PF09818.9 ABK73572.1 - 0.23 10.2 0.0 0.36 9.6 0.0 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class Pox_A32 PF04665.12 ABK73572.1 - 0.25 10.8 0.0 0.43 10.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein EFG_IV PF03764.18 ABK73573.1 - 5.5e-39 132.7 0.1 1.3e-38 131.5 0.1 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU PF00009.27 ABK73573.1 - 2.2e-35 122.0 0.0 3.1e-35 121.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 ABK73573.1 - 2.6e-25 88.2 0.0 1e-24 86.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.6 ABK73573.1 - 1.4e-24 86.0 0.0 2.4e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 ABK73573.1 - 2.8e-11 43.6 0.0 9.8e-11 41.9 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ABK73573.1 - 1.1e-06 28.7 0.1 4.6e-06 26.7 0.0 2.2 3 0 0 3 3 2 1 50S ribosome-binding GTPase Septin PF00735.18 ABK73573.1 - 0.00013 21.4 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Septin SRPRB PF09439.10 ABK73573.1 - 0.0076 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 ABK73573.1 - 0.011 16.3 0.0 0.026 15.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 ABK73573.1 - 0.02 14.6 0.0 0.049 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 ABK73573.1 - 0.03 14.7 0.0 0.072 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 ABK73573.1 - 0.046 13.8 0.1 5.8 6.9 0.0 2.3 1 1 1 2 2 2 0 Dynamin family RsgA_GTPase PF03193.16 ABK73573.1 - 0.046 13.6 0.3 0.24 11.3 0.2 2.2 2 1 0 2 2 2 0 RsgA GTPase AAA_28 PF13521.6 ABK73573.1 - 0.062 13.6 0.4 0.13 12.5 0.4 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ABK73573.1 - 0.074 13.5 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 ABK73573.1 - 0.08 12.7 0.0 4.7 6.9 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.17 ABK73573.1 - 0.11 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_21 PF13304.6 ABK73573.1 - 0.13 12.1 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 ABK73573.1 - 0.16 12.1 0.3 0.44 10.7 0.3 1.7 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 ABK73573.1 - 0.18 12.0 0.0 0.63 10.3 0.0 1.9 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase NmrA PF05368.13 ABK73574.1 - 1.9e-14 53.8 0.0 9.7e-14 51.5 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ABK73574.1 - 3.9e-12 46.4 0.1 5.7e-12 45.9 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ABK73574.1 - 8.9e-05 22.1 0.1 0.00025 20.6 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 ABK73574.1 - 0.00086 19.6 0.0 0.0018 18.6 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain GDP_Man_Dehyd PF16363.5 ABK73574.1 - 0.0071 15.8 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Optomotor-blind PF11078.8 ABK73574.1 - 0.089 13.4 0.1 0.28 11.8 0.0 1.8 2 0 0 2 2 2 0 Optomotor-blind protein N-terminal region adh_short PF00106.25 ABK73574.1 - 0.16 11.4 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.17 ABK73574.1 - 0.17 10.9 0.0 7.2 5.6 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain Hydrolase_6 PF13344.6 ABK73575.1 - 2.9e-20 72.2 0.0 1e-19 70.5 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ABK73575.1 - 7.9e-20 70.7 0.1 3.2e-19 68.8 0.2 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 ABK73575.1 - 3.4e-12 47.1 0.3 1.2e-11 45.3 0.3 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ABK73575.1 - 1.7e-09 38.1 0.0 1.7e-06 28.3 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 ABK73575.1 - 0.053 13.1 0.1 0.099 12.2 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase K_oxygenase PF13434.6 ABK73576.1 - 1e-99 334.0 0.0 1.2e-99 333.7 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 ABK73576.1 - 5.8e-12 45.5 0.0 4e-08 32.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ABK73576.1 - 2.7e-09 36.7 0.0 1.2e-05 24.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ABK73576.1 - 1.2e-07 31.9 0.7 2.4e-05 24.4 0.0 3.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 ABK73576.1 - 5.3e-06 26.3 1.3 0.0012 18.5 0.2 2.9 1 1 1 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 ABK73576.1 - 0.00057 19.3 0.1 0.049 12.9 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 ABK73576.1 - 0.12 12.9 0.3 3.8 8.1 0.0 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HAD PF12710.7 ABK73577.1 - 5.6e-31 108.4 0.6 6.8e-31 108.1 0.6 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ABK73577.1 - 2.4e-07 31.2 0.1 4.5e-07 30.4 0.1 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ABK73577.1 - 0.0011 18.8 0.0 0.27 10.9 0.0 2.7 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ABK73577.1 - 0.08 13.0 0.0 0.31 11.1 0.0 1.9 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 ABK73577.1 - 0.15 12.2 0.0 2.4 8.3 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Radical_SAM PF04055.21 ABK73579.1 - 5e-16 59.5 0.1 1e-15 58.5 0.1 1.5 1 0 0 1 1 1 1 Radical SAM superfamily BATS PF06968.13 ABK73579.1 - 5.1e-12 45.8 0.0 1.3e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain His_biosynth PF00977.21 ABK73579.1 - 0.073 12.5 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein TetR_N PF00440.23 ABK73580.1 - 1.1e-09 37.9 0.5 2.5e-09 36.8 0.2 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_7 PF02796.15 ABK73580.1 - 0.00017 21.6 0.0 0.00036 20.6 0.0 1.6 1 1 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 ABK73580.1 - 0.022 14.8 0.4 0.099 12.7 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn helix HTH_22 PF13309.6 ABK73580.1 - 0.046 13.8 0.2 0.091 12.9 0.2 1.4 1 0 0 1 1 1 0 HTH domain HTH_23 PF13384.6 ABK73580.1 - 0.082 12.7 1.2 0.31 10.9 0.1 2.4 2 1 0 2 2 2 0 Homeodomain-like domain HTH_11 PF08279.12 ABK73580.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 HTH domain NAD_binding_10 PF13460.6 ABK73581.1 - 7.8e-14 52.0 8.7 2.6e-10 40.5 1.9 2.4 1 1 1 2 2 2 2 NAD(P)H-binding NmrA PF05368.13 ABK73581.1 - 3.9e-11 42.9 2.8 3.5e-10 39.8 2.8 2.1 1 1 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 ABK73581.1 - 1.2e-10 41.0 1.7 0.00014 21.1 0.1 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain Epimerase PF01370.21 ABK73581.1 - 1.5e-05 24.6 2.0 0.0001 21.9 2.0 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 ABK73581.1 - 0.00089 19.4 1.4 0.0013 18.8 0.4 1.8 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus DUF4342 PF14242.6 ABK73582.1 - 1.8 8.6 3.2 2.4 8.2 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) Ribosomal_L17 PF01196.19 ABK73583.1 - 2.9e-37 127.4 0.1 2.9e-37 127.4 0.1 2.2 2 1 0 2 2 2 1 Ribosomal protein L17 DUF4604 PF15377.6 ABK73583.1 - 0.023 15.1 11.6 0.029 14.8 11.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Molybdopterin_N PF18364.1 ABK73583.1 - 0.045 13.8 0.0 0.17 11.9 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin oxidoreductase N-terminal domain SAPS PF04499.15 ABK73583.1 - 0.63 8.8 7.9 0.68 8.6 7.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RR_TM4-6 PF06459.12 ABK73583.1 - 2.6 7.8 12.5 2.9 7.6 12.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Alpha_GJ PF03229.13 ABK73583.1 - 4.8 7.8 12.2 51 4.4 12.2 2.1 1 1 0 1 1 1 0 Alphavirus glycoprotein J CT47 PF15623.6 ABK73583.1 - 5 6.9 26.3 6.4 6.5 26.3 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 Hid1 PF12722.7 ABK73583.1 - 9.7 4.2 6.4 11 4.0 6.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF21 PF01595.20 ABK73584.1 - 2.2e-40 138.2 6.8 2.9e-40 137.8 6.8 1.1 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 ABK73584.1 - 6.5e-10 39.3 0.1 0.0006 20.2 0.0 2.7 2 0 0 2 2 2 2 CBS domain MlaE PF02405.16 ABK73585.1 - 5.7e-52 176.5 30.5 7.4e-52 176.1 30.5 1.1 1 0 0 1 1 1 1 Permease MlaE HemY_N PF07219.13 ABK73585.1 - 0.6 10.3 0.0 0.6 10.3 0.0 3.2 3 0 0 3 3 3 0 HemY protein N-terminus HTH_AsnC-type PF13404.6 ABK73586.1 - 1.1e-28 98.8 14.4 9e-16 57.4 1.6 3.8 4 0 0 4 4 4 2 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 ABK73586.1 - 1.4e-20 72.6 0.1 2.2e-11 43.1 0.1 2.6 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding AsnC_trans_reg PF01037.21 ABK73586.1 - 8.2e-19 67.4 0.3 1e-08 35.0 0.2 2.5 2 0 0 2 2 2 2 Lrp/AsnC ligand binding domain HTH_11 PF08279.12 ABK73586.1 - 7.4e-07 29.0 0.1 0.00033 20.5 0.0 2.5 2 0 0 2 2 2 1 HTH domain HTH_28 PF13518.6 ABK73586.1 - 7.6e-07 29.2 0.7 0.035 14.2 0.1 3.0 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_DeoR PF08220.12 ABK73586.1 - 3.5e-06 26.7 0.2 0.067 12.9 0.2 2.5 2 0 0 2 2 2 2 DeoR-like helix-turn-helix domain HTH_23 PF13384.6 ABK73586.1 - 1.1e-05 25.1 1.1 0.017 14.9 0.2 2.6 2 0 0 2 2 2 2 Homeodomain-like domain Sigma70_r4_2 PF08281.12 ABK73586.1 - 1.2e-05 24.9 1.9 0.016 14.9 0.1 3.0 3 1 0 3 3 3 2 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.6 ABK73586.1 - 2.9e-05 23.4 1.0 0.17 11.3 0.2 2.6 2 0 0 2 2 2 2 Helix-turn-helix domain of transposase family ISL3 HTH_20 PF12840.7 ABK73586.1 - 3.7e-05 23.7 5.7 0.062 13.4 0.2 3.0 4 0 0 4 4 2 2 Helix-turn-helix domain Sigma70_r4 PF04545.16 ABK73586.1 - 0.00024 20.6 1.0 0.11 12.0 0.1 2.5 2 0 0 2 2 2 2 Sigma-70, region 4 MarR_2 PF12802.7 ABK73586.1 - 0.0021 17.9 6.9 0.048 13.6 0.1 4.3 5 0 0 5 5 5 1 MarR family HTH_38 PF13936.6 ABK73586.1 - 0.0029 17.3 0.5 0.87 9.4 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain GntR PF00392.21 ABK73586.1 - 0.0043 16.7 4.8 0.53 10.0 0.1 3.2 3 0 0 3 3 3 2 Bacterial regulatory proteins, gntR family MerR PF00376.23 ABK73586.1 - 0.0052 16.5 2.4 3 7.7 0.2 3.3 3 0 0 3 3 3 2 MerR family regulatory protein HTH_Mga PF08280.11 ABK73586.1 - 0.0088 16.1 0.0 0.03 14.3 0.0 1.8 2 0 0 2 2 2 1 M protein trans-acting positive regulator (MGA) HTH domain MarR PF01047.22 ABK73586.1 - 0.011 15.7 0.0 0.2 11.6 0.0 2.4 2 0 0 2 2 2 0 MarR family HTH_50 PF18024.1 ABK73586.1 - 0.016 14.8 0.2 0.05 13.2 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain GerE PF00196.19 ABK73586.1 - 0.064 12.8 0.0 5 6.7 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family DUF746 PF05344.11 ABK73586.1 - 0.083 12.7 0.0 0.68 9.8 0.0 2.4 3 0 0 3 3 3 0 Domain of Unknown Function (DUF746) HTH_36 PF13730.6 ABK73586.1 - 0.085 12.8 0.0 16 5.5 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_5 PF01022.20 ABK73586.1 - 0.11 12.3 0.0 20 5.2 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family PCI PF01399.27 ABK73586.1 - 0.14 12.7 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 PCI domain TrmB PF01978.19 ABK73586.1 - 0.16 11.9 0.3 5.2 7.0 0.0 2.8 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB BAT PF15915.5 ABK73586.1 - 5.2 6.9 15.9 0.31 10.9 2.5 2.8 2 1 1 3 3 3 0 GAF and HTH_10 associated domain Whib PF02467.16 ABK73587.1 - 4e-27 94.6 0.7 5e-27 94.3 0.7 1.1 1 0 0 1 1 1 1 Transcription factor WhiB Condensation PF00668.20 ABK73588.1 - 0.022 13.4 0.0 0.054 12.2 0.0 1.6 2 0 0 2 2 2 0 Condensation domain DUF309 PF03745.14 ABK73589.1 - 7.3e-19 67.2 0.1 1.8e-18 66.0 0.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF309) TPR_16 PF13432.6 ABK73589.1 - 0.0061 17.2 4.8 0.0061 17.2 4.8 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 ABK73589.1 - 0.031 15.1 5.7 0.46 11.4 0.7 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 ABK73589.1 - 0.63 10.0 0.1 0.63 10.0 0.1 2.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Sensor PF13796.6 ABK73590.1 - 3e-41 141.2 26.3 4.9e-41 140.5 26.3 1.4 1 0 0 1 1 1 1 Putative sensor HisKA_3 PF07730.13 ABK73590.1 - 1.6e-09 38.2 4.5 2.5e-09 37.5 2.6 2.3 2 0 0 2 2 2 1 Histidine kinase HATPase_c_2 PF13581.6 ABK73590.1 - 0.015 15.2 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain HATPase_c PF02518.26 ABK73590.1 - 0.018 15.6 0.0 0.043 14.3 0.0 1.8 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase VirB3 PF05101.13 ABK73590.1 - 6.7 7.0 7.5 2.5 8.4 2.5 2.3 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein MmoB_DmpM PF02406.17 ABK73591.1 - 1.5e-18 66.8 0.0 1.8e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 MmoB/DmpM family ETF_alpha PF00766.19 ABK73592.1 - 2.5e-36 123.5 1.7 5.9e-36 122.4 1.7 1.7 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.21 ABK73592.1 - 6.1e-32 111.0 10.3 6.1e-32 111.0 10.3 1.5 1 1 0 1 1 1 1 Electron transfer flavoprotein domain Na_H_Exchanger PF00999.21 ABK73593.1 - 7.6e-52 176.4 28.9 2e-51 175.0 28.9 1.6 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family DUF1706 PF08020.11 ABK73593.1 - 0.047 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1706) S6PP PF05116.13 ABK73593.1 - 0.18 11.3 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase Acyl-CoA_dh_M PF02770.19 ABK73594.1 - 3e-19 69.0 0.0 5.4e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ABK73594.1 - 2.6e-12 47.4 0.0 1.4e-11 45.0 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 ABK73594.1 - 2e-09 37.8 0.1 3.5e-09 37.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 ABK73594.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal TPP_enzyme_N PF02776.18 ABK73595.1 - 1.4e-48 164.7 0.6 5.1e-48 162.9 0.2 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 ABK73595.1 - 8.7e-29 100.3 0.0 7.5e-28 97.3 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 ABK73595.1 - 2.1e-26 92.3 0.1 4.6e-26 91.2 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 ABK73595.1 - 0.00024 20.9 0.1 0.00044 20.1 0.1 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg E1_dh PF00676.20 ABK73595.1 - 0.013 14.5 0.1 0.52 9.2 0.0 2.3 2 0 0 2 2 2 0 Dehydrogenase E1 component CcdA PF07362.12 ABK73595.1 - 0.024 15.1 0.1 0.18 12.3 0.1 2.3 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA XFP_N PF09364.10 ABK73595.1 - 0.18 10.6 0.0 0.78 8.5 0.0 1.9 2 0 0 2 2 2 0 XFP N-terminal domain p450 PF00067.22 ABK73596.1 - 4.2e-24 85.1 0.1 5.4e-21 74.9 0.1 3.0 2 1 0 2 2 2 2 Cytochrome P450 adh_short_C2 PF13561.6 ABK73597.1 - 3.3e-51 174.1 7.8 3.7e-51 173.9 7.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK73597.1 - 1.1e-49 168.5 1.5 1.4e-49 168.2 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK73597.1 - 1.3e-11 44.8 0.9 2e-11 44.2 0.9 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK73597.1 - 0.00011 21.7 1.0 0.00037 20.0 0.9 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 ABK73597.1 - 0.025 14.1 0.5 0.041 13.4 0.5 1.5 1 0 0 1 1 1 0 NmrA-like family Shikimate_DH PF01488.20 ABK73597.1 - 0.038 14.0 0.2 0.07 13.2 0.2 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 ABK73597.1 - 0.12 11.8 0.1 1.2 8.5 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase CoA_transf_3 PF02515.17 ABK73598.1 - 1.4e-102 343.6 0.0 1.6e-102 343.4 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III NUDIX PF00293.28 ABK73599.1 - 3.6e-15 56.2 0.2 5.2e-15 55.6 0.2 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 ABK73599.1 - 4.8e-09 36.2 0.0 7.6e-09 35.5 0.0 1.3 1 1 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.6 ABK73599.1 - 0.036 13.7 0.0 0.042 13.4 0.0 1.1 1 0 0 1 1 1 0 Nucleotide hydrolase HisKA_3 PF07730.13 ABK73601.1 - 1.7e-13 50.9 2.1 1.7e-13 50.9 2.1 2.7 3 0 0 3 3 3 1 Histidine kinase GAF_2 PF13185.6 ABK73601.1 - 0.0018 18.6 2.0 0.0025 18.1 0.4 2.2 2 1 1 3 3 3 1 GAF domain HATPase_c_2 PF13581.6 ABK73601.1 - 0.003 17.5 0.1 0.0067 16.4 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain GAF_3 PF13492.6 ABK73601.1 - 0.0064 16.8 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 GAF domain HATPase_c PF02518.26 ABK73601.1 - 0.0069 16.9 0.0 0.012 16.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase KH_9 PF17904.1 ABK73601.1 - 0.18 12.2 0.1 3.8 7.9 0.0 2.3 2 0 0 2 2 2 0 FMRP KH0 domain PPDK_N PF01326.19 ABK73602.1 - 5.2e-81 272.5 0.0 7.8e-81 271.9 0.0 1.2 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers_C PF02896.18 ABK73602.1 - 4.3e-64 216.5 0.0 6.3e-64 215.9 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.23 ABK73602.1 - 1.6e-27 95.0 1.7 4.9e-27 93.5 1.7 1.9 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain Amidinotransf PF02274.17 ABK73603.1 - 1.2e-101 340.3 0.0 1.3e-101 340.1 0.0 1.0 1 0 0 1 1 1 1 Amidinotransferase p450 PF00067.22 ABK73604.1 - 2.9e-30 105.4 0.1 5.3e-24 84.8 0.4 3.1 2 1 0 2 2 2 2 Cytochrome P450 FMN_red PF03358.15 ABK73605.1 - 2.9e-22 79.1 0.1 3.4e-22 78.9 0.1 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 ABK73605.1 - 4.4e-09 36.3 0.0 6e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold SMC_ScpB PF04079.16 ABK73607.1 - 2.9e-50 170.0 0.0 3.6e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Segregation and condensation complex subunit ScpB HTH_15 PF12324.8 ABK73607.1 - 0.00042 20.2 4.5 0.0069 16.3 0.4 2.6 2 0 0 2 2 2 2 Helix-turn-helix domain of alkylmercury lyase TetR_N PF00440.23 ABK73608.1 - 2e-14 53.1 0.1 4.2e-14 52.1 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family Lactamase_B PF00753.27 ABK73609.1 - 2.6e-19 70.0 8.4 4.3e-19 69.3 8.4 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily ABATE PF07336.11 ABK73610.1 - 2.5e-20 73.5 6.7 3.2e-20 73.1 6.7 1.2 1 0 0 1 1 1 1 Putative stress-induced transcription regulator zf-CGNR PF11706.8 ABK73610.1 - 1.2e-15 57.1 5.9 1.2e-15 57.1 5.9 1.9 3 0 0 3 3 3 1 CGNR zinc finger Abhydrolase_3 PF07859.13 ABK73611.1 - 9.6e-51 172.6 0.0 1.8e-50 171.8 0.0 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ABK73611.1 - 4.1e-10 39.1 0.0 5.7e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Thioesterase PF00975.20 ABK73611.1 - 0.0025 18.0 0.0 0.0042 17.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_2 PF02230.16 ABK73611.1 - 0.18 11.6 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase COesterase PF00135.28 ABK73611.1 - 0.19 10.6 0.2 8.5 5.1 0.1 2.1 2 0 0 2 2 2 0 Carboxylesterase family Methyltransf_25 PF13649.6 ABK73612.1 - 0.00017 22.2 0.2 0.00068 20.3 0.2 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABK73612.1 - 0.00063 20.3 0.3 0.0048 17.5 0.3 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABK73612.1 - 0.00084 19.2 0.0 0.005 16.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABK73612.1 - 0.00087 19.2 0.0 0.0024 17.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 ABK73612.1 - 0.0083 15.7 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_12 PF08242.12 ABK73612.1 - 0.032 14.9 0.1 0.44 11.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 ABK73612.1 - 0.059 12.9 0.1 0.2 11.2 0.1 1.8 2 0 0 2 2 2 0 Methyltransferase small domain DctP PF03480.13 ABK73613.1 - 1.7e-35 122.7 0.0 2.3e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein, family 7 Aminotran_4 PF01063.19 ABK73614.1 - 7.1e-42 143.8 0.0 8.6e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV SnoaL_2 PF12680.7 ABK73615.1 - 7.2e-05 23.4 0.0 0.0001 22.9 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 ABK73615.1 - 0.016 15.0 0.0 0.16 11.8 0.0 2.0 1 1 1 2 2 2 0 SnoaL-like polyketide cyclase SnoaL_4 PF13577.6 ABK73615.1 - 0.022 14.9 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like domain CMAS PF02353.20 ABK73616.1 - 4.8e-118 393.4 0.0 5.4e-118 393.2 0.0 1.0 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 ABK73616.1 - 1.2e-09 38.2 0.0 3.1e-09 36.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABK73616.1 - 2.6e-09 37.7 0.1 8.4e-09 36.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK73616.1 - 1.2e-07 32.4 0.0 2.8e-07 31.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABK73616.1 - 3.5e-07 30.8 0.1 2.2e-06 28.2 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 ABK73616.1 - 0.0025 16.8 0.0 0.0064 15.5 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_31 PF13847.6 ABK73616.1 - 0.016 15.0 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 ABK73616.1 - 0.034 13.9 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Endonuc-FokI_C PF09254.11 ABK73616.1 - 0.072 12.4 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal MetW PF07021.12 ABK73616.1 - 0.096 12.3 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.14 ABK73616.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Pilus_CpaD PF09476.10 ABK73616.1 - 0.14 11.9 0.1 4.9 6.8 0.0 2.1 2 0 0 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) Oxidored_q6 PF01058.22 ABK73617.1 - 6.8e-27 93.9 0.3 2.4e-26 92.1 0.0 1.9 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase, 20 Kd subunit NiFe_hyd_SSU_C PF14720.6 ABK73617.1 - 1.1e-24 86.5 2.6 2.2e-24 85.6 2.6 1.5 1 0 0 1 1 1 1 NiFe/NiFeSe hydrogenase small subunit C-terminal PseudoU_synth_2 PF00849.22 ABK73618.1 - 8.3e-31 107.2 0.0 1.5e-30 106.4 0.0 1.4 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 ABK73618.1 - 0.025 14.3 0.0 0.06 13.1 0.0 1.7 1 0 0 1 1 1 0 S4 domain Bac_luciferase PF00296.20 ABK73619.1 - 5.6e-63 213.2 3.9 7.7e-63 212.8 3.9 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase dCMP_cyt_deam_2 PF08211.12 ABK73620.1 - 0.0013 18.9 1.8 0.0016 18.7 1.8 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Big_1 PF02369.16 ABK73620.1 - 0.003 17.5 1.8 0.44 10.6 0.3 2.4 2 1 0 2 2 2 2 Bacterial Ig-like domain (group 1) Cytochrom_B_N_2 PF13631.6 ABK73621.1 - 1.4e-61 207.4 8.3 1.4e-61 207.4 8.3 1.9 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Cytochrome_B PF00033.19 ABK73621.1 - 2.5e-23 82.9 11.5 2.5e-23 82.9 11.5 2.8 2 1 0 2 2 2 1 Cytochrome b/b6/petB DUF4405 PF14358.6 ABK73621.1 - 0.0029 18.1 6.1 0.0029 18.1 6.1 3.8 3 2 0 3 3 3 1 Domain of unknown function (DUF4405) DUF3382 PF11862.8 ABK73621.1 - 2.8 8.3 7.3 1.3 9.4 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) DUF1989 PF09347.10 ABK73622.1 - 2.4e-39 134.7 0.0 2.9e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Molybdopterin PF00384.22 ABK73623.1 - 5.7e-59 200.2 0.0 7e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 ABK73623.1 - 5.5e-23 81.1 0.0 1e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdopterin_N PF18364.1 ABK73623.1 - 1.5e-14 53.7 1.3 7.1e-14 51.5 0.3 2.5 2 0 0 2 2 2 1 Molybdopterin oxidoreductase N-terminal domain F420H2_quin_red PF04075.14 ABK73624.1 - 6.8e-34 116.8 0.0 7.7e-34 116.6 0.0 1.0 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase Lipase_GDSL_3 PF14606.6 ABK73625.1 - 9.9e-17 61.6 0.0 2.4e-16 60.4 0.0 1.6 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_2 PF13472.6 ABK73625.1 - 5.1e-11 43.3 1.0 2.7e-10 40.9 1.0 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family AA_kinase PF00696.28 ABK73626.1 - 2e-55 188.0 2.1 3.1e-55 187.4 2.1 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 ABK73626.1 - 1.4e-20 72.8 0.2 2.6e-16 59.2 0.1 2.5 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 ABK73626.1 - 2e-19 69.0 0.4 2.8e-10 39.8 0.0 2.9 2 0 0 2 2 2 2 ACT domain ACT_6 PF13740.6 ABK73626.1 - 0.016 15.1 0.1 10 6.2 0.0 2.8 2 0 0 2 2 2 0 ACT domain DUF4350 PF14258.6 ABK73626.1 - 0.1 13.0 0.1 6.9 7.2 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4350) PepSY_TM PF03929.16 ABK73627.1 - 0.043 13.5 0.0 0.045 13.4 0.0 1.1 1 0 0 1 1 1 0 PepSY-associated TM region ArsC PF03960.15 ABK73628.1 - 3.8e-11 42.8 0.0 4.9e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 ArsC family Glutaredoxin PF00462.24 ABK73628.1 - 0.00015 21.9 0.0 0.00021 21.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin GerD PF17898.1 ABK73628.1 - 0.2 11.6 0.0 0.32 11.0 0.0 1.2 1 0 0 1 1 1 0 Spore germination GerD central core domain Usp PF00582.26 ABK73630.1 - 1.7e-22 80.4 0.7 3.1e-22 79.6 0.7 1.4 1 0 0 1 1 1 1 Universal stress protein family MFS_1 PF07690.16 ABK73630.1 - 9.1e-19 67.6 57.5 2e-17 63.1 19.3 2.5 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 ABK73630.1 - 0.0006 18.8 0.3 0.0012 17.8 0.3 1.5 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM DUF4079 PF13301.6 ABK73630.1 - 0.02 15.0 2.3 0.02 15.0 2.3 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF4079) ZnuA PF01297.17 ABK73631.1 - 1e-69 234.8 0.0 1.1e-69 234.6 0.0 1.0 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic TRCF PF03461.15 ABK73631.1 - 0.05 14.0 0.0 0.094 13.1 0.0 1.4 1 0 0 1 1 1 0 TRCF domain MHB PF16525.5 ABK73632.1 - 1.8e-26 92.2 1.0 2.9e-26 91.5 1.0 1.4 1 0 0 1 1 1 1 Haemophore, haem-binding VHL_C PF17211.3 ABK73632.1 - 0.18 11.9 0.2 0.64 10.1 0.1 1.9 2 0 0 2 2 2 0 VHL box domain Ribosomal_L13 PF00572.18 ABK73633.1 - 1.5e-54 183.6 0.0 1.8e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 adh_short_C2 PF13561.6 ABK73634.1 - 3.9e-49 167.3 10.0 1.1e-48 165.8 10.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK73634.1 - 9.2e-43 146.0 6.4 1.5e-42 145.3 6.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Aldolase_II PF00596.21 ABK73634.1 - 1.1e-22 80.9 0.0 9.6e-22 77.8 0.0 2.3 2 0 0 2 2 2 1 Class II Aldolase and Adducin N-terminal domain KR PF08659.10 ABK73634.1 - 9.2e-09 35.5 5.3 1.9e-08 34.4 5.3 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK73634.1 - 0.0011 18.5 0.4 0.0019 17.7 0.4 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ABK73634.1 - 0.011 14.7 0.3 0.017 14.1 0.3 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF4519 PF15012.6 ABK73635.1 - 0.09 13.0 0.3 0.09 13.0 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) TrkA_TMD PF18613.1 ABK73635.1 - 0.2 11.1 8.7 1.6 8.3 0.3 3.4 2 0 0 2 2 2 0 Tyrosine kinase receptor A trans-membrane domain Lipase_GDSL_2 PF13472.6 ABK73636.1 - 3.2e-06 27.7 0.0 7e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ABK73636.1 - 0.092 12.7 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Methyltransf_25 PF13649.6 ABK73637.1 - 2.8e-11 44.0 0.0 5.1e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABK73637.1 - 5.8e-11 42.9 0.0 1.9e-10 41.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK73637.1 - 9.3e-11 42.4 0.0 1.4e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABK73637.1 - 2e-07 30.9 0.0 3.3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABK73637.1 - 5.7e-05 23.0 0.0 8.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 ABK73637.1 - 0.00042 20.1 0.0 0.0018 18.0 0.0 2.0 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 ABK73637.1 - 0.02 14.4 0.0 0.05 13.2 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Epimerase PF01370.21 ABK73638.1 - 3.2e-25 89.0 0.0 5.4e-25 88.3 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ABK73638.1 - 3e-16 59.7 0.0 4.1e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ABK73638.1 - 1e-15 57.5 0.0 1.4e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 ABK73638.1 - 4.3e-15 56.1 0.1 6.3e-15 55.5 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ABK73638.1 - 7.4e-11 42.1 0.1 6.7e-10 38.9 0.2 2.2 3 0 0 3 3 3 1 NmrA-like family NAD_binding_4 PF07993.12 ABK73638.1 - 8.2e-11 41.6 2.9 2.7e-08 33.3 2.9 2.8 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 ABK73638.1 - 1.9e-05 24.0 0.0 2.8e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 ABK73638.1 - 0.00022 21.2 2.8 0.0017 18.3 2.8 2.2 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 ABK73638.1 - 0.00061 19.3 0.7 0.0018 17.8 0.7 1.8 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 ABK73638.1 - 0.00061 19.0 0.1 0.00085 18.5 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short_C2 PF13561.6 ABK73638.1 - 0.043 13.4 0.1 0.89 9.1 0.0 2.3 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Glyco_trans_4_4 PF13579.6 ABK73638.1 - 0.12 12.8 8.8 3.1 8.2 6.8 3.1 1 1 1 2 2 2 0 Glycosyl transferase 4-like domain NAD_kinase PF01513.21 ABK73639.1 - 4.5e-72 242.7 0.0 5.2e-72 242.5 0.0 1.0 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 ABK73639.1 - 0.086 12.5 0.1 0.19 11.3 0.1 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain GATase PF00117.28 ABK73639.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Response_reg PF00072.24 ABK73640.1 - 1e-27 96.5 0.0 1.7e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 ABK73640.1 - 3.8e-24 84.6 0.1 6.3e-23 80.7 0.0 2.2 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal FleQ PF06490.11 ABK73640.1 - 0.0091 16.4 0.0 0.012 16.0 0.0 1.3 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ B12-binding_2 PF02607.17 ABK73640.1 - 0.057 13.9 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain FAM199X PF15814.5 ABK73641.1 - 0.67 9.0 4.3 0.81 8.7 4.3 1.0 1 0 0 1 1 1 0 Protein family FAM199X E1-E2_ATPase PF00122.20 ABK73642.1 - 3e-46 157.2 2.9 6.5e-46 156.1 2.9 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 ABK73642.1 - 5.7e-38 131.3 6.0 1.2e-37 130.2 6.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ABK73642.1 - 0.00019 21.3 0.2 0.00033 20.5 0.2 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Form_Nir_trans PF01226.17 ABK73643.1 - 6.1e-33 114.1 17.4 6.9e-33 114.0 17.4 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter Ribosomal_S19 PF00203.21 ABK73644.1 - 5.5e-37 125.5 0.4 6.2e-37 125.3 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S19 NUDIX PF00293.28 ABK73645.1 - 2.1e-17 63.4 0.1 2.4e-17 63.2 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.6 ABK73645.1 - 0.034 13.7 0.0 0.042 13.4 0.0 1.1 1 0 0 1 1 1 0 Nucleotide hydrolase UreD PF01774.17 ABK73647.1 - 1.5e-23 83.8 0.2 2e-23 83.4 0.2 1.2 1 0 0 1 1 1 1 UreD urease accessory protein DUF2840 PF11000.8 ABK73647.1 - 0.061 13.1 0.0 14 5.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2840) Aldedh PF00171.22 ABK73648.1 - 3.5e-153 510.4 0.0 3.9e-153 510.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family YCII PF03795.14 ABK73648.1 - 0.11 13.0 0.2 0.84 10.1 0.1 2.6 1 1 1 2 2 2 0 YCII-related domain Aldedh PF00171.22 ABK73649.1 - 3.8e-143 477.3 0.0 4.7e-143 477.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF2007 PF09413.10 ABK73649.1 - 0.049 13.8 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Putative prokaryotic signal transducing protein DUF3301 PF11743.8 ABK73650.1 - 0.21 11.3 0.1 0.27 11.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) Transglycosylas PF06737.14 ABK73651.1 - 2.5e-34 117.7 6.8 4.6e-34 116.9 6.8 1.5 1 0 0 1 1 1 1 Transglycosylase-like domain DUF348 PF03990.14 ABK73651.1 - 1.3e-27 95.3 12.8 3.1e-10 39.6 0.3 3.9 4 0 0 4 4 4 3 G5-linked-Ubiquitin-like domain G5 PF07501.12 ABK73651.1 - 6.6e-16 58.5 0.1 2.2e-15 56.9 0.1 2.0 2 0 0 2 2 2 1 G5 domain Fer2_4 PF13510.6 ABK73651.1 - 0.11 12.5 0.3 21 5.2 0.0 2.7 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Acyl_CoA_thio PF02551.15 ABK73653.1 - 1e-49 167.8 0.0 1.6e-42 144.5 0.0 3.0 2 1 1 3 3 3 3 Acyl-CoA thioesterase 4HBT_3 PF13622.6 ABK73653.1 - 4e-48 164.8 0.2 4.6e-48 164.6 0.2 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 ABK73653.1 - 0.0038 17.5 0.1 0.011 16.1 0.1 1.7 2 0 0 2 2 2 1 Thioesterase superfamily Mal_decarbox_Al PF16957.5 ABK73654.1 - 3.8e-177 589.9 0.0 4.8e-177 589.6 0.0 1.0 1 0 0 1 1 1 1 Malonate decarboxylase, alpha subunit, transporter CoA_trans PF01144.23 ABK73654.1 - 0.034 13.5 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 Coenzyme A transferase SBP_bac_5 PF00496.22 ABK73656.1 - 1.7e-81 274.1 4.6 2.5e-81 273.6 4.6 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle TATR PF03430.13 ABK73656.1 - 0.096 11.1 0.0 0.14 10.5 0.0 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator FluMu_N PF17891.1 ABK73656.1 - 0.13 12.0 0.1 0.43 10.4 0.1 1.9 1 0 0 1 1 1 0 Mu-like prophage FluMu N-terminal domain Ribosomal_L27 PF01016.19 ABK73657.1 - 2.5e-36 123.6 2.5 2.8e-36 123.4 2.5 1.0 1 0 0 1 1 1 1 Ribosomal L27 protein DASH_Dad1 PF08649.10 ABK73658.1 - 0.093 12.9 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 DASH complex subunit Dad1 SCP2 PF02036.17 ABK73658.1 - 0.17 12.4 0.0 0.27 11.8 0.0 1.5 1 1 0 1 1 1 0 SCP-2 sterol transfer family Big_10 PF17964.1 ABK73659.1 - 1.8e-59 200.8 1.8 2.7e-59 200.2 1.8 1.3 1 0 0 1 1 1 1 Bacterial Ig domain YkuD PF03734.14 ABK73659.1 - 6.3e-16 59.1 0.2 1.5e-15 57.9 0.2 1.7 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain Big_5 PF13205.6 ABK73659.1 - 0.00024 21.7 2.1 0.78 10.5 0.0 2.9 1 1 1 2 2 2 2 Bacterial Ig-like domain Ring_hydroxyl_A PF00848.19 ABK73660.1 - 5.7e-46 157.2 1.2 7.7e-46 156.8 1.2 1.1 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 ABK73660.1 - 3.3e-14 52.6 0.0 5.6e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Metallophos_2 PF12850.7 ABK73661.1 - 2.3e-11 44.1 0.0 1.2e-10 41.9 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 ABK73661.1 - 7.4e-09 36.4 0.1 9.8e-09 36.0 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase AcetDehyd-dimer PF09290.11 ABK73662.1 - 7.1e-64 214.1 0.5 1e-63 213.6 0.5 1.2 1 0 0 1 1 1 1 Prokaryotic acetaldehyde dehydrogenase, dimerisation Semialdhyde_dh PF01118.24 ABK73662.1 - 6.7e-10 39.5 0.0 1.5e-08 35.1 0.0 2.5 3 1 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 ABK73662.1 - 0.019 15.8 0.0 0.044 14.6 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Acyl-CoA_dh_M PF02770.19 ABK73663.1 - 2.8e-21 75.5 0.0 4.7e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 ABK73663.1 - 6.8e-12 45.8 0.1 9.8e-12 45.3 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK73663.1 - 1.1e-06 29.2 0.2 3.8e-06 27.5 0.0 2.0 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Bac_luciferase PF00296.20 ABK73664.1 - 6.5e-37 127.6 7.3 3.3e-35 122.0 7.3 2.2 1 1 0 1 1 1 1 Luciferase-like monooxygenase CLP_protease PF00574.23 ABK73665.1 - 6.2e-75 251.1 0.0 7.4e-75 250.8 0.0 1.0 1 0 0 1 1 1 1 Clp protease Abhydrolase_1 PF00561.20 ABK73666.1 - 2.9e-23 82.8 0.1 1.4e-22 80.6 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK73666.1 - 1.6e-15 58.3 13.2 2e-15 58.0 13.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK73666.1 - 0.00028 20.3 0.0 0.0008 18.7 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 ABK73666.1 - 0.013 15.6 0.0 0.016 15.4 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Ndr PF03096.14 ABK73666.1 - 0.13 10.9 0.0 0.41 9.3 0.0 1.7 1 1 0 1 1 1 0 Ndr family p450 PF00067.22 ABK73667.1 - 6.3e-17 61.5 0.5 4e-14 52.2 0.5 3.0 1 1 0 1 1 1 1 Cytochrome P450 Acetyltransf_1 PF00583.25 ABK73668.1 - 3.3e-14 53.1 0.0 4.1e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ABK73668.1 - 4.1e-12 46.1 0.0 6.2e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ABK73668.1 - 1.9e-09 37.8 0.0 2.7e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ABK73668.1 - 7.4e-06 26.7 0.0 9.2e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_18 PF18014.1 ABK73668.1 - 0.0052 16.6 0.0 0.96 9.3 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 ABK73668.1 - 0.0061 16.5 0.0 0.0092 15.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 ABK73668.1 - 0.013 15.1 0.0 0.023 14.4 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ABK73668.1 - 0.12 12.6 0.0 0.3 11.2 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain AhpC-TSA PF00578.21 ABK73669.1 - 7.4e-34 116.3 0.1 1.1e-33 115.8 0.1 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ABK73669.1 - 6.4e-15 55.1 0.1 7.2e-15 55.0 0.1 1.1 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.14 ABK73669.1 - 0.00038 20.4 0.0 0.00079 19.3 0.0 1.4 1 0 0 1 1 1 1 SCO1/SenC Acyl-CoA_dh_1 PF00441.24 ABK73670.1 - 1.9e-48 164.5 3.7 1.9e-48 164.5 3.7 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK73670.1 - 1.3e-30 106.4 0.3 3.4e-30 105.0 0.3 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ABK73670.1 - 2e-26 92.0 0.0 4e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ABK73670.1 - 1.4e-20 73.9 1.2 2.6e-20 73.1 1.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Vault PF01505.18 ABK73670.1 - 0.13 12.5 0.2 0.93 9.7 0.0 2.4 3 0 0 3 3 3 0 Major Vault Protein repeat domain PucR PF07905.11 ABK73670.1 - 0.13 12.5 0.0 0.57 10.5 0.0 2.0 2 0 0 2 2 2 0 Purine catabolism regulatory protein-like family Putative_PNPOx PF01243.20 ABK73671.1 - 2.1e-13 50.3 0.0 2.9e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase HTH_17 PF12728.7 ABK73672.1 - 1.1e-10 41.6 0.0 1.5e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain TOBE PF03459.17 ABK73672.1 - 1.4e-09 38.1 0.7 2.4e-09 37.3 0.7 1.4 1 0 0 1 1 1 1 TOBE domain MerR PF00376.23 ABK73672.1 - 6.4e-06 25.8 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 MerR family regulatory protein HTH_Tnp_ISL3 PF13542.6 ABK73672.1 - 6.4e-05 22.3 0.1 0.00015 21.1 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 MerR_1 PF13411.6 ABK73672.1 - 0.00012 22.1 0.0 0.00018 21.5 0.0 1.2 1 0 0 1 1 1 1 MerR HTH family regulatory protein HTH_29 PF13551.6 ABK73672.1 - 0.00048 20.1 0.0 0.00092 19.2 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 ABK73672.1 - 0.00078 19.2 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_31 PF13560.6 ABK73672.1 - 0.0009 19.5 0.2 0.0033 17.7 0.2 1.9 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_DeoR PF08220.12 ABK73672.1 - 0.00096 18.9 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_28 PF13518.6 ABK73672.1 - 0.0011 19.0 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain AbiEi_4 PF13338.6 ABK73672.1 - 0.035 14.3 0.2 0.075 13.2 0.1 1.6 2 0 0 2 2 1 0 Transcriptional regulator, AbiEi antitoxin Phage_terminase PF10668.9 ABK73672.1 - 0.049 13.7 0.1 0.081 13.0 0.1 1.3 1 0 0 1 1 1 0 Phage terminase small subunit Sigma70_r4_2 PF08281.12 ABK73672.1 - 0.058 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 DUF3853 PF12964.7 ABK73672.1 - 0.068 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3853) DUF746 PF05344.11 ABK73672.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) HTH_36 PF13730.6 ABK73672.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain MIP PF00230.20 ABK73673.1 - 8.3e-52 176.2 9.0 9.4e-52 176.0 9.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein MerC PF03203.14 ABK73673.1 - 6.6 7.2 8.7 0.24 11.9 1.2 2.3 2 1 0 2 2 2 0 MerC mercury resistance protein ParBc PF02195.18 ABK73674.1 - 2.2e-25 88.8 1.1 3.2e-25 88.2 0.4 1.7 2 0 0 2 2 2 1 ParB-like nuclease domain HTH_ParB PF17762.1 ABK73674.1 - 5.9e-16 58.0 1.2 1.5e-15 56.8 1.2 1.7 1 0 0 1 1 1 1 HTH domain found in ParB protein TrmB PF01978.19 ABK73674.1 - 0.0057 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 ABK73674.1 - 0.062 13.2 1.0 15 5.6 0.0 2.8 2 0 0 2 2 2 0 MarR family HTH_38 PF13936.6 ABK73674.1 - 0.066 13.0 0.1 1.1 9.1 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain SoPB_HTH PF18090.1 ABK73674.1 - 0.078 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Centromere-binding protein HTH domain HTH_Crp_2 PF13545.6 ABK73674.1 - 0.094 12.7 0.5 0.24 11.4 0.1 2.0 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_23 PF13384.6 ABK73674.1 - 0.1 12.4 0.7 5.6 6.9 0.0 3.1 3 0 0 3 3 3 0 Homeodomain-like domain DUF3052 PF11253.8 ABK73676.1 - 2.8e-55 185.6 5.6 3.2e-55 185.4 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3052) Aminotran_3 PF00202.21 ABK73676.1 - 0.042 12.5 0.0 0.047 12.3 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-III DUF1876 PF08962.11 ABK73677.1 - 4.3e-28 97.1 0.1 5.4e-28 96.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1876) NTP_transf_3 PF12804.7 ABK73679.1 - 0.0013 19.1 0.0 0.0023 18.3 0.0 1.4 1 1 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 ABK73679.1 - 0.2 11.2 0.0 0.34 10.5 0.0 1.4 1 1 0 1 1 1 0 Nucleotidyl transferase Cutinase PF01083.22 ABK73680.1 - 9.8e-44 149.4 0.1 1.2e-43 149.2 0.1 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_6 PF12697.7 ABK73680.1 - 5.7e-06 27.1 2.8 7.5e-06 26.7 2.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.11 ABK73680.1 - 0.0031 17.1 0.0 0.0046 16.6 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.16 ABK73680.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF2974 PF11187.8 ABK73680.1 - 0.16 11.5 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) cobW PF02492.19 ABK73681.1 - 3.5e-42 144.0 0.4 4.4e-42 143.7 0.4 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 ABK73681.1 - 1.6e-22 79.2 0.0 3e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.27 ABK73681.1 - 0.00032 20.3 0.0 0.18 11.3 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ABK73681.1 - 0.00081 19.3 0.1 0.18 11.7 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase MobB PF03205.14 ABK73681.1 - 0.0012 18.7 0.4 0.0072 16.2 0.1 2.4 2 1 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MeaB PF03308.16 ABK73681.1 - 0.0017 17.4 1.3 0.69 8.8 0.1 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 ABK73681.1 - 0.0058 16.7 0.1 0.015 15.3 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase TsaE PF02367.17 ABK73681.1 - 0.0096 15.9 0.1 0.02 14.9 0.1 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 ABK73681.1 - 0.013 15.9 0.5 0.043 14.2 0.5 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 ABK73681.1 - 0.037 14.2 0.1 0.059 13.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ABK73681.1 - 0.064 13.8 0.1 0.15 12.6 0.1 1.6 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 ABK73681.1 - 0.086 13.4 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1_Xtn PF16897.5 ABK73681.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain CAP59_mtransfer PF11735.8 ABK73681.1 - 0.17 11.5 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 AAA_30 PF13604.6 ABK73681.1 - 1.2 8.8 5.0 5.8 6.6 5.0 2.1 1 1 0 1 1 1 0 AAA domain CobD_Cbib PF03186.13 ABK73682.1 - 4.2e-87 291.9 2.8 5.2e-87 291.6 2.8 1.1 1 0 0 1 1 1 1 CobD/Cbib protein DUF4401 PF14351.6 ABK73682.1 - 0.0072 15.7 1.7 2.1 7.6 1.7 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF4401) CobU PF02283.16 ABK73683.1 - 1.2e-53 181.1 0.1 1.4e-53 180.9 0.1 1.0 1 0 0 1 1 1 1 Cobinamide kinase / cobinamide phosphate guanyltransferase NMT1_2 PF13379.6 ABK73683.1 - 0.004 16.9 0.5 0.0043 16.8 0.5 1.2 1 0 0 1 1 1 1 NMT1-like family Peripla_BP_3 PF13377.6 ABK73684.1 - 3.1e-34 118.7 3.3 5.3e-34 117.9 1.1 2.1 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 ABK73684.1 - 7.4e-19 68.2 0.0 9.8e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 ABK73684.1 - 3.1e-10 39.7 1.4 7e-10 38.5 0.1 2.3 3 0 0 3 3 3 1 Bacterial regulatory proteins, lacI family HTH_38 PF13936.6 ABK73684.1 - 0.04 13.7 0.0 0.09 12.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 ABK73684.1 - 0.076 12.4 1.1 0.89 9.0 0.1 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 Peripla_BP_4 PF13407.6 ABK73684.1 - 0.076 12.6 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein domain HTH_AraC PF00165.23 ABK73684.1 - 0.22 11.7 0.0 0.43 10.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family cwf21 PF08312.12 ABK73685.1 - 0.0096 16.1 0.7 0.011 15.8 0.7 1.3 1 0 0 1 1 1 1 cwf21 domain Oxidored_FMN PF00724.20 ABK73686.1 - 1.2e-64 218.7 0.0 4.2e-63 213.7 0.0 2.0 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Aldedh PF00171.22 ABK73687.1 - 1.5e-167 557.8 0.0 1.8e-167 557.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Lactamase_B_2 PF12706.7 ABK73689.1 - 6.9e-17 61.6 1.6 2.1e-08 33.9 0.1 2.1 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ABK73689.1 - 2.3e-14 53.9 0.8 2.3e-14 53.9 0.8 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 ABK73689.1 - 3e-05 23.6 0.0 7.6e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease PolyA_pol PF01743.20 ABK73691.1 - 6.5e-33 113.9 0.1 1.4e-32 112.8 0.1 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 ABK73691.1 - 3.3e-17 62.0 0.0 6.5e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A HD PF01966.22 ABK73691.1 - 2e-14 53.8 0.7 4.1e-14 52.9 0.7 1.5 1 0 0 1 1 1 1 HD domain tRNA_NucTran2_2 PF13735.6 ABK73691.1 - 3.9e-08 33.4 0.0 1.9e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 tRNA nucleotidyltransferase domain 2 putative ICL PF00463.21 ABK73692.1 - 2.4e-101 339.8 1.8 8e-53 179.7 0.1 2.1 1 1 1 2 2 2 2 Isocitrate lyase family PEP_mutase PF13714.6 ABK73692.1 - 5.3e-15 55.5 0.1 1.2e-14 54.4 0.1 1.5 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ParA PF10609.9 ABK73693.1 - 2.4e-86 289.2 0.2 3.2e-86 288.8 0.2 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase FeS_assembly_P PF01883.19 ABK73693.1 - 8.7e-19 67.5 0.4 3.3e-18 65.6 0.4 2.1 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein CbiA PF01656.23 ABK73693.1 - 1.6e-15 57.3 0.0 2.8e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 ABK73693.1 - 3.2e-08 33.7 0.4 9.5e-07 28.9 0.4 2.2 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 ABK73693.1 - 1e-06 28.2 0.0 1.9e-06 27.3 0.0 1.5 2 0 0 2 2 2 1 ATPase MipZ Fer4_NifH PF00142.18 ABK73693.1 - 1e-05 25.1 0.0 0.00013 21.5 0.0 2.2 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.6 ABK73693.1 - 0.00017 21.4 1.4 0.17 11.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain ArsA_ATPase PF02374.15 ABK73693.1 - 0.004 16.4 0.5 0.007 15.6 0.2 1.5 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.6 ABK73693.1 - 0.0051 16.4 0.0 0.012 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain CLP1_P PF16575.5 ABK73693.1 - 0.041 13.7 0.0 0.075 12.8 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop VirC1 PF07015.11 ABK73693.1 - 0.044 13.1 0.2 0.089 12.1 0.2 1.4 1 0 0 1 1 1 0 VirC1 protein CBP_BcsQ PF06564.12 ABK73693.1 - 0.077 12.5 0.6 1.3 8.4 0.4 2.4 3 0 0 3 3 3 0 Cellulose biosynthesis protein BcsQ APS_kinase PF01583.20 ABK73693.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase SIS_2 PF13580.6 ABK73693.1 - 0.16 12.0 1.0 0.69 9.9 0.0 2.3 2 0 0 2 2 2 0 SIS domain Amdase PF17645.1 ABK73694.1 - 1.1e-28 100.3 0.2 1.4e-28 100.1 0.2 1.0 1 0 0 1 1 1 1 Arylmalonate decarboxylase Asp_Glu_race PF01177.22 ABK73694.1 - 9e-07 29.0 0.1 1.2e-06 28.6 0.1 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase DUF1246 PF06849.12 ABK73694.1 - 0.04 13.9 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1246) CoA_binding_2 PF13380.6 ABK73694.1 - 0.12 12.8 2.5 0.94 10.0 0.3 2.8 1 1 1 2 2 2 0 CoA binding domain NrfD PF03916.14 ABK73695.1 - 8.4e-22 78.2 1.4 8.4e-22 78.2 1.4 1.7 2 0 0 2 2 2 1 Polysulphide reductase, NrfD Amidohydro_3 PF07969.11 ABK73696.1 - 9.7e-18 64.9 1.3 1e-11 45.0 0.2 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 ABK73696.1 - 1.1e-06 28.2 0.7 0.035 13.4 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family FAD_binding_2 PF00890.24 ABK73696.1 - 0.0088 15.2 0.1 0.02 14.0 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_76 PF03663.14 ABK73697.1 - 3.1e-32 112.5 0.0 3.9e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 CrgA PF06781.12 ABK73698.1 - 2.9e-31 107.4 1.1 3.2e-31 107.2 1.1 1.0 1 0 0 1 1 1 1 Cell division protein CrgA FixP_N PF14715.6 ABK73698.1 - 3.4 7.5 8.6 0.22 11.3 3.3 1.6 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP AhpC-TSA PF00578.21 ABK73700.1 - 5.2e-14 52.2 0.0 6.6e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ABK73700.1 - 3.5e-12 46.3 0.0 4.4e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin PF00085.20 ABK73700.1 - 4.8e-05 23.3 0.0 0.00029 20.8 0.0 1.9 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 ABK73700.1 - 0.00012 22.5 0.0 0.00031 21.2 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ABK73700.1 - 0.0037 17.6 0.0 0.0051 17.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Pentapeptide PF00805.22 ABK73700.1 - 0.061 13.0 3.1 0.3 10.8 0.1 2.3 2 0 0 2 2 2 0 Pentapeptide repeats (8 copies) Thioredoxin_9 PF14595.6 ABK73700.1 - 0.16 11.8 0.0 0.29 10.9 0.0 1.4 2 0 0 2 2 2 0 Thioredoxin Titin_Z PF09042.11 ABK73700.1 - 0.22 11.5 4.4 0.48 10.4 4.4 1.5 1 0 0 1 1 1 0 Titin Z 2-Hacid_dh_C PF02826.19 ABK73701.1 - 4.5e-47 159.7 0.0 6.9e-47 159.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ABK73701.1 - 2.8e-11 43.2 0.0 4.8e-11 42.5 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ThiF PF00899.21 ABK73701.1 - 0.0035 16.7 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 ThiF family NAD_binding_2 PF03446.15 ABK73701.1 - 0.033 14.4 0.0 0.065 13.4 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.25 ABK73701.1 - 0.4 10.1 1.6 0.61 9.5 0.2 2.0 3 0 0 3 3 3 0 short chain dehydrogenase Ku PF02735.16 ABK73702.1 - 1.3e-41 142.6 0.2 1.8e-41 142.1 0.2 1.2 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain TF_Zn_Ribbon PF08271.12 ABK73702.1 - 0.0021 17.6 1.2 0.0056 16.2 0.2 2.1 2 0 0 2 2 2 1 TFIIB zinc-binding HC2 PF07382.11 ABK73702.1 - 0.0072 16.4 18.3 0.01 15.9 18.3 1.2 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 RP-C_C PF11800.8 ABK73702.1 - 0.49 10.5 6.2 0.77 9.8 5.9 1.5 2 0 0 2 2 2 0 Replication protein C C-terminal region ATP11 PF06644.11 ABK73702.1 - 7.5 6.3 10.8 11 5.8 10.8 1.2 1 0 0 1 1 1 0 ATP11 protein LapA_dom PF06305.11 ABK73703.1 - 1e-09 38.1 0.3 1e-09 38.1 0.3 2.0 2 0 0 2 2 2 1 Lipopolysaccharide assembly protein A domain PRIMA1 PF16101.5 ABK73703.1 - 0.058 13.4 1.6 0.085 12.9 1.6 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Phage_holin_3_6 PF07332.11 ABK73703.1 - 0.083 12.9 10.2 0.11 12.6 10.2 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III PBP_N PF17093.5 ABK73703.1 - 6.2 7.1 7.6 9.4 6.5 6.4 1.8 1 1 1 2 2 2 0 Penicillin-binding protein N-terminus AhpC-TSA PF00578.21 ABK73704.1 - 1.1e-06 28.6 0.0 1.8e-06 27.8 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family AhpC-TSA_2 PF13911.6 ABK73704.1 - 0.02 15.0 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme NIF3 PF01784.18 ABK73705.1 - 7.7e-60 202.6 0.0 1.2e-59 201.9 0.0 1.2 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Trans_reg_C PF00486.28 ABK73706.1 - 2.4e-26 91.6 0.0 2.9e-25 88.1 0.0 2.1 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 ABK73706.1 - 3.6e-25 88.3 0.0 5.1e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain TPP_enzyme_N PF02776.18 ABK73707.1 - 4.4e-25 88.3 1.0 1.3e-24 86.8 1.0 1.8 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 ABK73707.1 - 2e-05 24.4 0.1 0.0011 18.8 0.0 2.5 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SBP_bac_3 PF00497.20 ABK73708.1 - 4.3e-51 173.5 0.0 5.3e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 ABK73708.1 - 0.025 14.8 0.0 0.81 9.9 0.0 2.2 1 1 0 1 1 1 0 Ligated ion channel L-glutamate- and glycine-binding site NAD_binding_10 PF13460.6 ABK73709.1 - 8.2e-19 68.2 0.4 1.1e-18 67.8 0.4 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ABK73709.1 - 3e-13 49.9 0.0 3.8e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 ABK73709.1 - 2.1e-08 34.0 1.8 2.5e-07 30.4 0.1 2.4 2 1 1 3 3 3 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 ABK73709.1 - 4e-06 27.3 0.0 8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.25 ABK73709.1 - 3.1e-05 23.5 0.1 5e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 ABK73709.1 - 4.8e-05 22.6 0.1 6.6e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 ABK73709.1 - 0.0084 16.0 3.8 0.033 14.1 1.2 2.6 1 1 1 2 2 2 1 KR domain Semialdhyde_dh PF01118.24 ABK73709.1 - 0.012 16.0 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 ABK73709.1 - 0.03 13.4 0.8 0.77 8.8 0.1 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 ABK73709.1 - 0.048 12.6 0.0 0.21 10.5 0.0 1.9 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family CoA_binding_2 PF13380.6 ABK73709.1 - 0.068 13.7 0.0 0.17 12.4 0.0 1.9 1 1 0 1 1 1 0 CoA binding domain adh_short_C2 PF13561.6 ABK73709.1 - 0.088 12.3 0.3 0.14 11.7 0.3 1.5 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NAD_binding_2 PF03446.15 ABK73709.1 - 0.09 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase GDP_Man_Dehyd PF16363.5 ABK73709.1 - 0.1 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DapB_N PF01113.20 ABK73709.1 - 0.13 12.4 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PP-binding PF00550.25 ABK73710.1 - 6.5e-17 61.7 0.6 7.6e-17 61.4 0.1 1.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site Ribosomal_L50 PF10501.9 ABK73710.1 - 0.00026 21.1 0.0 0.0003 20.9 0.0 1.2 1 1 0 1 1 1 1 Ribosomal subunit 39S PP-binding_2 PF14573.6 ABK73710.1 - 0.09 13.0 0.2 0.1 12.8 0.2 1.1 1 0 0 1 1 1 0 Acyl-carrier UbiA PF01040.18 ABK73711.1 - 2.4e-64 217.1 27.9 3.2e-64 216.7 27.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family NUDIX PF00293.28 ABK73712.1 - 1.8e-10 41.0 0.1 2.5e-10 40.5 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.6 ABK73712.1 - 0.24 10.9 0.0 0.35 10.4 0.0 1.2 1 0 0 1 1 1 0 Nucleotide hydrolase Lactamase_B_2 PF12706.7 ABK73713.1 - 1e-18 67.6 1.3 1.3e-18 67.2 1.3 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ABK73713.1 - 6.3e-11 42.4 0.1 1e-10 41.7 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ABK73713.1 - 0.00072 19.6 2.0 0.004 17.2 2.0 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily SspH PF08141.12 ABK73713.1 - 0.056 13.6 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Small acid-soluble spore protein H family MerR_1 PF13411.6 ABK73714.1 - 2.1e-18 66.1 0.0 3e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR-DNA-bind PF09278.11 ABK73714.1 - 2.4e-15 56.8 0.6 3.5e-15 56.3 0.6 1.2 1 0 0 1 1 1 1 MerR, DNA binding MerR PF00376.23 ABK73714.1 - 5.4e-14 51.7 2.3 8.4e-14 51.1 2.3 1.3 1 0 0 1 1 1 1 MerR family regulatory protein HTH_17 PF12728.7 ABK73714.1 - 0.002 18.2 0.2 0.0037 17.4 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 ABK73714.1 - 0.0035 17.7 1.2 0.028 14.8 0.1 2.5 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 ABK73714.1 - 0.015 15.6 0.1 1.1 9.6 0.0 2.8 3 0 0 3 3 3 0 Transposase HTH_3 PF01381.22 ABK73714.1 - 0.016 15.3 0.0 0.14 12.2 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix AbiEi_4 PF13338.6 ABK73714.1 - 0.019 15.1 1.1 0.044 13.9 0.1 2.1 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin TetR_N PF00440.23 ABK73714.1 - 0.13 12.1 0.5 0.35 10.7 0.3 1.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family Cyt_c_ox_IV PF12270.8 ABK73715.1 - 5.2 7.2 7.6 5.1 7.2 2.1 2.6 2 1 0 2 2 2 0 Cytochrome c oxidase subunit IV HicB PF05534.12 ABK73716.1 - 1.3e-18 66.5 0.0 2.1e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 HicB family NEL PF14496.6 ABK73716.1 - 0.0077 15.7 0.2 0.013 15.0 0.2 1.3 1 1 0 1 1 1 1 C-terminal novel E3 ligase, LRR-interacting FA_desaturase PF00487.24 ABK73718.1 - 0.04 13.7 3.4 0.044 13.6 3.4 1.0 1 0 0 1 1 1 0 Fatty acid desaturase PrgI PF12666.7 ABK73718.1 - 0.069 13.9 2.0 0.077 13.7 2.0 1.1 1 0 0 1 1 1 0 PrgI family protein VHP PF02209.19 ABK73718.1 - 0.19 11.9 0.0 0.26 11.4 0.0 1.2 1 0 0 1 1 1 0 Villin headpiece domain Wzy_C_2 PF11846.8 ABK73718.1 - 0.21 11.5 3.4 0.25 11.3 3.4 1.1 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal DUF4191 PF13829.6 ABK73718.1 - 0.26 10.6 1.0 0.29 10.4 1.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF2207 PF09972.9 ABK73718.1 - 0.27 10.0 0.9 0.29 9.8 0.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF485 PF04341.12 ABK73718.1 - 1.5 8.9 6.2 1.9 8.5 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF485 DUF3040 PF11239.8 ABK73718.1 - 2.9 8.2 8.2 6 7.2 8.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) PRiA4_ORF3 PF07929.11 ABK73719.1 - 2.1e-51 174.1 0.0 2.5e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein DUF202 PF02656.15 ABK73720.1 - 0.005 17.3 0.1 0.0091 16.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF202) HTH_18 PF12833.7 ABK73721.1 - 1.8e-13 50.5 0.1 3.4e-13 49.7 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 ABK73721.1 - 1.3e-05 25.1 0.0 0.098 12.8 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family GerE PF00196.19 ABK73721.1 - 0.18 11.4 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family adh_short PF00106.25 ABK73722.1 - 1e-42 145.8 0.0 1.5e-42 145.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK73722.1 - 7e-35 120.7 1.1 9.7e-35 120.2 1.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK73722.1 - 9.8e-12 45.1 0.0 1.5e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 ABK73722.1 - 0.0075 16.2 0.3 0.014 15.3 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 ABK73722.1 - 0.011 15.2 0.2 0.042 13.3 0.2 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Oxidored_nitro PF00148.19 ABK73722.1 - 0.05 12.3 0.1 0.069 11.9 0.1 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase FAD_binding_2 PF00890.24 ABK73723.1 - 5.9e-87 292.4 7.3 8.5e-87 291.9 7.3 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 ABK73723.1 - 3.4e-15 56.1 0.1 7.6e-15 55.0 0.1 1.6 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term FAD_binding_3 PF01494.19 ABK73723.1 - 6.2e-08 32.3 1.9 2.5e-07 30.3 1.4 2.1 2 1 0 2 2 2 1 FAD binding domain DAO PF01266.24 ABK73723.1 - 5.6e-07 29.5 6.8 7e-07 29.1 4.6 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ABK73723.1 - 2.5e-06 26.9 0.7 4.6e-05 22.8 0.4 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ABK73723.1 - 3.8e-05 22.6 0.1 0.002 16.9 0.1 2.7 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_3 PF13738.6 ABK73723.1 - 0.0015 17.8 0.1 0.0062 15.8 0.0 2.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ABK73723.1 - 0.0019 18.4 0.2 0.0076 16.5 0.2 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ABK73723.1 - 0.005 16.1 0.5 0.11 11.7 0.1 2.4 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 ABK73723.1 - 0.0086 15.2 0.8 0.027 13.6 0.7 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 ABK73723.1 - 0.0093 16.5 0.7 0.075 13.6 0.4 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ABK73723.1 - 0.011 15.7 3.4 0.058 13.4 1.9 2.8 3 1 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 ABK73723.1 - 0.033 14.6 0.0 0.09 13.2 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding YjeF_N PF03853.15 ABK73723.1 - 0.045 13.7 0.0 0.15 11.9 0.1 1.9 2 0 0 2 2 2 0 YjeF-related protein N-terminus 3HCDH_N PF02737.18 ABK73723.1 - 0.048 13.5 0.3 0.097 12.5 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 ABK73723.1 - 0.11 12.2 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Rieske PF00355.26 ABK73724.1 - 5.3e-14 51.9 0.0 8.9e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain WASH-7_mid PF14744.6 ABK73724.1 - 0.17 11.0 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 WASH complex subunit 7 FAD_binding_3 PF01494.19 ABK73726.1 - 6.2e-06 25.7 0.1 2.1e-05 23.9 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 ABK73726.1 - 0.0011 18.1 0.0 0.0018 17.4 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_2 PF00890.24 ABK73726.1 - 0.0054 15.9 0.9 0.0096 15.0 0.1 1.9 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 ABK73726.1 - 0.0066 15.7 0.6 1.8 7.7 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ABK73726.1 - 0.0097 14.8 0.0 2 7.1 0.0 2.8 3 0 0 3 3 3 1 Tryptophan halogenase Thi4 PF01946.17 ABK73726.1 - 0.037 13.3 0.3 1.8 7.8 0.0 2.3 2 0 0 2 2 2 0 Thi4 family GMC_oxred_N PF00732.19 ABK73726.1 - 0.064 12.6 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 GMC oxidoreductase DUF1188 PF06690.11 ABK73726.1 - 0.13 11.8 0.1 14 5.1 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1188) SymE_toxin PF08845.10 ABK73726.1 - 0.16 12.0 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 Toxin SymE, type I toxin-antitoxin system YCII PF03795.14 ABK73727.1 - 3.7e-10 40.1 0.0 4.6e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 YCII-related domain Ribosomal_L18A PF01775.17 ABK73727.1 - 0.081 13.0 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A HAD_2 PF13419.6 ABK73728.1 - 6.1e-32 111.1 0.0 7.1e-32 110.9 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ABK73728.1 - 5.4e-18 66.1 0.3 4.3e-16 59.9 0.3 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ABK73728.1 - 3.8e-11 43.8 0.3 6e-11 43.1 0.3 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ABK73728.1 - 3.8e-09 36.5 0.7 9e-09 35.3 0.2 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Acid_PPase PF12689.7 ABK73728.1 - 0.00042 20.2 0.0 0.017 15.0 0.0 2.3 1 1 0 1 1 1 1 Acid Phosphatase Hydrolase_3 PF08282.12 ABK73728.1 - 0.0011 18.7 0.0 1 9.0 0.0 2.8 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 ABK73728.1 - 0.0031 17.6 0.0 0.51 10.5 0.0 2.4 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase S6PP PF05116.13 ABK73728.1 - 0.23 11.0 0.0 3.6 7.1 0.0 2.2 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase GAF_2 PF13185.6 ABK73729.1 - 8.1e-12 45.6 0.3 3.1e-11 43.7 0.3 2.1 1 0 0 1 1 1 1 GAF domain DUF4118 PF13493.6 ABK73729.1 - 8.5e-12 44.8 5.8 2.2e-11 43.5 5.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4118) GAF PF01590.26 ABK73729.1 - 1.7e-10 41.6 0.0 4.1e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 ABK73729.1 - 2.3e-08 34.4 0.9 9.2e-08 32.5 0.0 2.3 3 0 0 3 3 3 1 GAF domain HisKA_3 PF07730.13 ABK73729.1 - 6.1e-08 33.1 1.0 6.1e-08 33.1 1.0 2.7 2 0 0 2 2 2 1 Histidine kinase HATPase_c PF02518.26 ABK73729.1 - 3e-05 24.5 0.2 0.002 18.6 0.2 2.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 ABK73729.1 - 0.12 12.4 0.0 0.12 12.4 0.0 2.2 3 0 0 3 3 3 0 Histidine kinase-like ATPase domain PocR PF10114.9 ABK73729.1 - 0.24 11.2 0.1 22 4.8 0.0 2.2 2 0 0 2 2 2 0 Sensory domain found in PocR Mg_chelatase PF01078.21 ABK73730.1 - 1.1e-08 34.8 0.1 0.0011 18.4 0.0 2.7 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 ABK73730.1 - 1.3e-07 31.4 0.0 4.2e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.14 ABK73730.1 - 5.4e-07 29.7 0.1 0.0089 16.0 0.0 2.6 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 ABK73730.1 - 9e-06 25.6 0.0 4.6e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MCM PF00493.23 ABK73730.1 - 9.6e-05 21.6 0.0 0.0038 16.3 0.0 2.2 2 0 0 2 2 2 1 MCM P-loop domain AAA_PrkA PF08298.11 ABK73730.1 - 0.0007 18.6 0.0 0.0078 15.2 0.0 2.0 2 0 0 2 2 2 1 PrkA AAA domain AAA_16 PF13191.6 ABK73730.1 - 0.002 18.5 1.2 0.013 15.9 1.2 2.5 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 ABK73730.1 - 0.0027 18.2 0.0 0.013 16.0 0.0 2.1 3 0 0 3 3 3 1 ABC transporter NACHT PF05729.12 ABK73730.1 - 0.052 13.5 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 ABK73730.1 - 0.14 12.4 0.0 0.46 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain DLIC PF05783.11 ABK73730.1 - 0.2 10.5 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) CbbQ_C PF08406.10 ABK73730.1 - 0.48 10.7 4.3 0.17 12.2 1.1 1.9 2 0 0 2 2 2 0 CbbQ/NirQ/NorQ C-terminal Acetyltransf_3 PF13302.7 ABK73731.1 - 3e-17 63.6 0.0 3.9e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Peripla_BP_4 PF13407.6 ABK73733.1 - 5.8e-58 196.5 11.9 7.5e-58 196.1 11.9 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 ABK73733.1 - 1.5e-16 60.7 0.2 1.9e-16 60.4 0.2 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 ABK73733.1 - 9.8e-06 26.0 0.0 0.00017 21.9 0.0 2.3 1 1 1 2 2 2 1 Periplasmic binding protein-like domain Rod_cone_degen PF15201.6 ABK73734.1 - 0.048 13.8 0.2 0.64 10.2 0.0 2.6 3 0 0 3 3 3 0 Progressive rod-cone degeneration FAD_binding_2 PF00890.24 ABK73735.1 - 1.4e-24 86.9 12.2 9.1e-23 81.0 12.2 3.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ABK73735.1 - 6.7e-12 45.2 0.0 3.7e-08 33.0 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ABK73735.1 - 3.6e-09 36.7 6.2 0.00029 20.5 2.9 2.6 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ABK73735.1 - 1.4e-07 31.3 2.6 2.5e-07 30.4 2.5 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ABK73735.1 - 9.7e-07 27.8 2.4 2.3e-06 26.6 0.1 2.5 2 1 0 2 2 2 1 HI0933-like protein Succ_DH_flav_C PF02910.20 ABK73735.1 - 4.7e-05 23.4 0.2 9.2e-05 22.4 0.2 1.4 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 ABK73735.1 - 0.0031 16.7 2.2 0.046 12.8 3.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 ABK73735.1 - 0.0031 18.0 0.1 1.8 9.2 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ABK73735.1 - 0.0062 15.8 1.5 0.0083 15.4 0.6 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 ABK73735.1 - 0.0095 16.4 0.0 0.022 15.2 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 ABK73735.1 - 0.013 14.8 0.1 0.02 14.2 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 ABK73735.1 - 0.023 14.0 0.2 0.11 11.7 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ABK73736.1 - 1.5e-21 76.9 0.0 7.7e-21 74.6 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ABK73736.1 - 3.8e-16 59.2 0.0 2.2e-14 53.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ABK73736.1 - 6.9e-14 51.2 0.0 6.6e-13 47.9 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ABK73736.1 - 5.1e-11 42.6 0.0 1.2e-09 38.2 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 ABK73736.1 - 1.3e-10 40.9 0.1 2.5e-07 30.2 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 ABK73736.1 - 1.6e-09 37.9 0.0 0.00021 21.0 0.0 3.1 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ABK73736.1 - 2.3e-06 27.7 0.5 0.062 13.3 0.0 4.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding GIDA PF01134.22 ABK73736.1 - 0.00012 21.3 0.0 0.019 14.0 0.0 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 ABK73736.1 - 0.00033 19.9 0.1 0.00087 18.5 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 ABK73736.1 - 0.00049 19.5 0.0 0.046 13.0 0.0 2.2 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 ABK73736.1 - 0.00062 18.7 0.1 0.025 13.4 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.14 ABK73736.1 - 0.00066 18.5 0.0 0.45 9.2 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 ABK73736.1 - 0.00097 19.7 0.1 0.47 11.0 0.0 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ABK73736.1 - 0.0058 15.9 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 ABK73736.1 - 0.0081 15.5 0.1 0.03 13.7 0.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 ABK73736.1 - 0.014 15.5 0.0 1.5 8.9 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 ABK73736.1 - 0.014 14.5 0.0 3.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 ABK73736.1 - 0.17 11.1 0.0 4.4 6.4 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain ABC_tran PF00005.27 ABK73737.1 - 2.8e-28 99.1 0.0 3.7e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK73737.1 - 1.6e-09 38.0 0.4 7.7e-05 22.6 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK73737.1 - 9.4e-08 31.8 0.0 0.0019 17.7 0.0 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 ABK73737.1 - 3.8e-06 26.8 0.0 4.6e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 ABK73737.1 - 4.4e-05 23.1 0.0 8.5e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.9 ABK73737.1 - 0.00011 21.1 0.0 0.014 14.2 0.0 2.5 2 1 0 2 2 2 1 Predicted ATPase of the ABC class AAA_16 PF13191.6 ABK73737.1 - 0.00019 21.9 0.3 0.0006 20.2 0.3 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 ABK73737.1 - 0.00024 21.7 0.0 0.00034 21.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_27 PF13514.6 ABK73737.1 - 0.0095 15.5 0.0 0.023 14.3 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ABK73737.1 - 0.016 14.9 0.1 0.036 13.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 ABK73737.1 - 0.017 15.2 0.0 0.062 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ABK73737.1 - 0.021 15.0 0.1 0.063 13.4 0.1 1.9 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.6 ABK73737.1 - 0.034 14.4 0.1 0.097 13.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ABK73737.1 - 0.05 13.2 0.2 0.33 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ABK73737.1 - 0.079 12.9 0.1 0.83 9.6 0.0 2.2 2 0 0 2 2 2 0 NACHT domain ATPase_2 PF01637.18 ABK73737.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea FCD PF07729.12 ABK73738.1 - 2e-19 70.2 4.0 3.7e-19 69.4 4.0 1.4 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 ABK73738.1 - 1.9e-15 56.2 0.7 3.9e-15 55.2 0.7 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_11 PF08279.12 ABK73738.1 - 7.9e-06 25.7 0.2 1.7e-05 24.6 0.2 1.5 1 0 0 1 1 1 1 HTH domain HTH_24 PF13412.6 ABK73738.1 - 1.9e-05 24.1 0.2 3.5e-05 23.3 0.2 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Rrf2 PF02082.20 ABK73738.1 - 6.4e-05 23.2 0.1 0.00014 22.2 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulator HTH_Crp_2 PF13545.6 ABK73738.1 - 0.00063 19.7 0.3 0.0014 18.5 0.3 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain TrmB PF01978.19 ABK73738.1 - 0.00077 19.3 0.0 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.7 ABK73738.1 - 0.0024 17.9 0.3 0.0084 16.1 0.3 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 ABK73738.1 - 0.0025 17.6 1.0 0.0059 16.4 0.2 2.0 2 0 0 2 2 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 ABK73738.1 - 0.0028 17.5 2.0 0.0044 16.9 0.5 2.1 2 0 0 2 2 2 1 MarR family HTH_10 PF04967.12 ABK73738.1 - 0.0056 16.5 0.1 0.12 12.2 0.0 2.3 2 0 0 2 2 2 1 HTH DNA binding domain HTH_41 PF14502.6 ABK73738.1 - 0.0067 16.1 0.1 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_DeoR PF08220.12 ABK73738.1 - 0.0089 15.8 0.1 0.017 14.9 0.1 1.4 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain TFIIE_alpha PF02002.17 ABK73738.1 - 0.011 15.5 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 TFIIE alpha subunit HTH_23 PF13384.6 ABK73738.1 - 0.013 15.3 0.1 0.059 13.2 0.1 2.1 2 0 0 2 2 2 0 Homeodomain-like domain MarR PF01047.22 ABK73738.1 - 0.018 15.0 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_CodY PF08222.11 ABK73738.1 - 0.036 13.6 0.1 0.063 12.8 0.1 1.3 1 0 0 1 1 1 0 CodY helix-turn-helix domain HTH_27 PF13463.6 ABK73738.1 - 0.039 14.5 0.1 0.087 13.3 0.1 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_28 PF13518.6 ABK73738.1 - 0.039 14.1 0.1 0.039 14.1 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain Fe_dep_repress PF01325.19 ABK73738.1 - 0.05 13.8 0.0 0.088 13.0 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_36 PF13730.6 ABK73738.1 - 0.057 13.4 0.0 0.094 12.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_5 PF01022.20 ABK73738.1 - 0.061 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Transketolase_C PF02780.20 ABK73739.1 - 2e-25 89.1 0.5 5.8e-25 87.6 0.2 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 ABK73739.1 - 1.2e-24 87.0 0.3 2.8e-24 85.8 0.1 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain PFOR_II PF17147.4 ABK73739.1 - 0.0032 17.8 0.2 0.0089 16.3 0.2 1.8 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Lar_N PF09861.9 ABK73739.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Lactate racemase N-terminal domain DUF2190 PF09956.9 ABK73739.1 - 1.8 9.1 5.0 5.4 7.6 0.0 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2190) BPD_transp_1 PF00528.22 ABK73740.1 - 2.6e-25 89.2 20.0 2.6e-25 89.2 20.0 1.9 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component HTH_3 PF01381.22 ABK73741.1 - 0.014 15.5 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix HTH_23 PF13384.6 ABK73741.1 - 0.016 15.0 0.0 0.22 11.4 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain HTH_10 PF04967.12 ABK73741.1 - 0.039 13.8 0.0 13 5.7 0.0 2.4 2 0 0 2 2 2 0 HTH DNA binding domain HTH_11 PF08279.12 ABK73741.1 - 0.044 13.7 0.0 0.99 9.4 0.0 2.2 2 0 0 2 2 2 0 HTH domain HTH_28 PF13518.6 ABK73741.1 - 0.054 13.6 0.0 0.3 11.2 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain PUFD PF16553.5 ABK73741.1 - 0.11 12.7 0.1 0.15 12.2 0.1 1.2 1 0 0 1 1 1 0 BCORL-PCGF1-binding domain HTH_24 PF13412.6 ABK73741.1 - 0.12 12.0 0.0 1.1 8.8 0.0 2.3 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding YajC PF02699.15 ABK73742.1 - 5.5e-19 67.8 0.1 6.8e-19 67.5 0.1 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Peptidase_S11 PF00768.20 ABK73743.1 - 2.7e-32 112.1 0.0 4.1e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 ABK73743.1 - 5.6e-09 35.9 0.0 7.3e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase enzyme family Transpeptidase PF00905.22 ABK73743.1 - 0.011 15.0 0.1 0.39 9.9 0.0 2.2 2 0 0 2 2 2 0 Penicillin binding protein transpeptidase domain Complex1_51K PF01512.17 ABK73744.1 - 1.2e-44 151.8 0.0 1.6e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 ABK73744.1 - 5.5e-32 109.7 0.0 9e-32 109.0 0.0 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 ABK73744.1 - 1.8e-09 37.3 0.0 4e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 SLBB domain HEPN_AbiU2 PF18734.1 ABK73744.1 - 0.15 11.6 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 AbiU2 LCM PF04072.14 ABK73745.1 - 2.1e-50 171.3 0.3 3.5e-50 170.6 0.3 1.4 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase BPD_transp_1 PF00528.22 ABK73747.1 - 2.9e-14 53.2 16.3 2.9e-14 53.2 16.3 2.0 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF2909 PF11137.8 ABK73747.1 - 0.51 10.3 0.0 0.51 10.3 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2909) FBPase_glpX PF03320.13 ABK73748.1 - 7.3e-141 468.4 5.0 8.3e-141 468.3 5.0 1.0 1 0 0 1 1 1 1 Bacterial fructose-1,6-bisphosphatase, glpX-encoded Abhydrolase_6 PF12697.7 ABK73749.1 - 1.8e-13 51.6 11.6 1.8e-13 51.6 11.6 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK73749.1 - 4.1e-12 45.9 0.2 1e-07 31.5 0.1 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 ABK73749.1 - 2.8e-10 40.0 0.3 1.9e-09 37.3 0.1 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 ABK73749.1 - 7e-10 39.0 0.1 4.3e-08 33.1 0.1 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF1100 PF06500.11 ABK73749.1 - 7.5e-08 31.6 0.0 1.3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) DLH PF01738.18 ABK73749.1 - 1.6e-06 27.9 0.1 0.0018 17.9 0.0 2.4 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 ABK73749.1 - 0.0013 18.7 0.1 0.0025 17.7 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold LIP PF03583.14 ABK73749.1 - 0.0077 15.6 0.2 0.07 12.4 0.1 2.0 2 0 0 2 2 2 1 Secretory lipase Peptidase_S15 PF02129.18 ABK73749.1 - 0.011 15.3 0.3 0.086 12.4 0.0 2.3 1 1 1 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) PUA PF01472.20 ABK73749.1 - 0.07 13.1 0.1 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 PUA domain AXE1 PF05448.12 ABK73749.1 - 0.14 10.8 0.2 0.65 8.6 0.1 1.9 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 ABK73749.1 - 0.15 11.9 0.0 0.78 9.6 0.0 1.9 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Amidohydro_2 PF04909.14 ABK73750.1 - 4.5e-28 98.9 6.0 5.5e-28 98.6 6.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Sdh_cyt PF01127.22 ABK73751.1 - 9.3e-25 87.0 1.9 1.2e-24 86.6 1.9 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Fumarate_red_D PF02313.17 ABK73751.1 - 0.006 16.7 2.6 0.0089 16.1 2.6 1.3 1 0 0 1 1 1 1 Fumarate reductase subunit D Fumarate_red_C PF02300.17 ABK73751.1 - 0.0065 16.6 3.7 0.055 13.5 3.5 1.9 1 1 0 1 1 1 1 Fumarate reductase subunit C Ferric_reduct PF01794.19 ABK73751.1 - 0.096 12.8 7.6 0.35 11.0 7.6 1.8 1 1 0 1 1 1 0 Ferric reductase like transmembrane component MIase PF02426.16 ABK73752.1 - 2.9e-42 142.7 0.1 3.2e-42 142.6 0.1 1.0 1 0 0 1 1 1 1 Muconolactone delta-isomerase MlaD PF02470.20 ABK73753.1 - 1.3e-13 51.0 0.1 2.6e-13 50.1 0.1 1.6 1 0 0 1 1 1 1 MlaD protein Mce4_CUP1 PF11887.8 ABK73753.1 - 4.4e-06 26.3 0.3 9.3e-06 25.3 0.1 1.6 2 0 0 2 2 2 1 Cholesterol uptake porter CUP1 of Mce4, putative DUF5345 PF17280.2 ABK73753.1 - 0.22 11.5 1.4 0.51 10.4 1.4 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5345) CMD PF02627.20 ABK73754.1 - 6.6e-11 42.1 0.4 1.2e-05 25.2 0.0 2.3 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family Oxidored_molyb PF00174.19 ABK73755.1 - 0.00038 20.1 0.0 0.0087 15.7 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase molybdopterin binding domain MMPL PF03176.15 ABK73756.1 - 1.8e-189 628.7 31.3 3.2e-101 338.6 6.2 3.0 3 0 0 3 3 3 2 MMPL family CinA_KH PF18146.1 ABK73756.1 - 0.13 12.4 0.4 0.41 10.8 0.4 1.8 1 0 0 1 1 1 0 Damage-inducible protein CinA KH domain CHASE3 PF05227.13 ABK73756.1 - 4.6 7.1 7.4 0.77 9.7 0.4 2.3 2 0 0 2 2 2 0 CHASE3 domain PGI PF00342.19 ABK73757.1 - 1.1e-204 680.5 0.0 1.3e-204 680.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase TetR_C_11 PF16859.5 ABK73758.1 - 1.5e-23 83.2 5.5 1.5e-23 83.2 5.5 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK73758.1 - 4.8e-17 61.5 2.1 9.4e-17 60.5 0.4 2.2 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_7 PF14246.6 ABK73758.1 - 0.031 14.3 0.2 0.056 13.5 0.2 1.5 1 0 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal domain LacI PF00356.21 ABK73758.1 - 0.091 12.6 0.4 0.37 10.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_Tnp_1_2 PF13022.6 ABK73758.1 - 0.1 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase LysM PF01476.20 ABK73759.1 - 9.8e-09 35.1 0.0 6.5e-05 22.9 0.0 3.7 3 1 0 3 3 3 2 LysM domain LPD18 PF18832.1 ABK73759.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 18 BPD_transp_2 PF02653.16 ABK73761.1 - 1.9e-30 105.9 32.2 3.6e-30 105.1 32.2 1.5 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component DUF624 PF04854.14 ABK73761.1 - 0.53 10.4 0.0 0.53 10.4 0.0 3.8 3 2 0 3 3 3 0 Protein of unknown function, DUF624 SurE PF01975.17 ABK73762.1 - 7.6e-45 153.1 0.0 9.5e-45 152.8 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE MNHE PF01899.16 ABK73763.1 - 1.9e-36 125.0 6.4 2.2e-36 124.8 6.4 1.0 1 0 0 1 1 1 1 Na+/H+ ion antiporter subunit DUF421 PF04239.12 ABK73764.1 - 5.7e-11 42.2 0.0 7.9e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF421) CopD PF05425.13 ABK73764.1 - 0.019 15.3 5.8 0.019 15.3 5.8 1.9 1 1 1 2 2 2 0 Copper resistance protein D Ribosomal_S15 PF00312.22 ABK73765.1 - 3e-36 123.5 1.7 3.4e-36 123.3 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S15 ACP_syn_III_C PF08541.10 ABK73766.1 - 8.4e-24 83.6 0.0 1.6e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 ABK73766.1 - 2.8e-10 39.9 0.8 2.8e-10 39.9 0.8 1.9 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FAE1_CUT1_RppA PF08392.12 ABK73766.1 - 0.04 13.2 0.0 0.63 9.3 0.0 2.2 2 0 0 2 2 2 0 FAE1/Type III polyketide synthase-like protein DDOST_48kD PF03345.14 ABK73767.1 - 0.00073 18.5 0.0 0.001 18.0 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta GerE PF00196.19 ABK73768.1 - 4.3e-17 61.4 0.0 9.3e-17 60.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family TPR_12 PF13424.6 ABK73768.1 - 0.00099 19.4 27.4 0.061 13.6 3.6 5.9 5 2 1 6 6 6 4 Tetratricopeptide repeat SNAP PF14938.6 ABK73768.1 - 0.04 13.3 0.0 0.13 11.7 0.0 1.8 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 ABK73768.1 - 0.092 12.9 0.1 0.092 12.9 0.1 7.4 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_14 PF13428.6 ABK73768.1 - 0.16 12.9 0.1 0.16 12.9 0.1 7.7 7 2 1 8 8 8 0 Tetratricopeptide repeat TPR_11 PF13414.6 ABK73768.1 - 0.34 10.6 5.7 8 6.2 0.0 4.3 5 0 0 5 5 5 0 TPR repeat TPR_8 PF13181.6 ABK73768.1 - 0.36 11.1 2.7 86 3.7 0.0 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 ABK73768.1 - 0.56 10.1 11.1 0.85 9.5 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 ABK73768.1 - 3.4 8.5 15.0 0.5 11.1 0.2 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 ABK73768.1 - 6.2 7.6 34.6 7.9 7.2 0.2 6.2 5 0 0 5 5 5 0 Tetratricopeptide repeat EamA PF00892.20 ABK73769.1 - 1.2e-14 54.6 29.9 2.3e-08 34.3 14.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family Sugar_transport PF06800.12 ABK73769.1 - 5.8e-05 22.6 16.4 6.5e-05 22.4 16.4 1.1 1 0 0 1 1 1 1 Sugar transport protein DUF2569 PF10754.9 ABK73769.1 - 3.7 8.0 7.7 0.44 11.0 3.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) DUF4381 PF14316.6 ABK73769.1 - 4.5 7.5 7.1 1 9.6 2.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4381) Acetyltransf_1 PF00583.25 ABK73770.1 - 1.5e-19 70.3 0.1 1.9e-19 70.0 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ABK73770.1 - 9e-16 58.0 0.0 1.1e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ABK73770.1 - 9.1e-16 58.1 0.1 1.3e-15 57.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ABK73770.1 - 1.8e-09 37.4 0.0 3e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 ABK73770.1 - 5.8e-07 29.3 0.0 1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ABK73770.1 - 1e-06 29.5 0.0 1.3e-06 29.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ABK73770.1 - 1.2e-06 28.6 0.0 2.5e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ABK73770.1 - 1.6e-05 25.1 0.0 2.4e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ABK73770.1 - 0.0009 19.3 0.1 0.0017 18.5 0.1 1.5 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_6 PF13480.7 ABK73770.1 - 0.0056 16.8 0.2 0.0079 16.4 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_18 PF18014.1 ABK73770.1 - 0.097 12.5 0.0 1.2 9.0 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 ABK73770.1 - 0.24 10.9 0.0 0.33 10.5 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase NAD_binding_2 PF03446.15 ABK73771.1 - 3.3e-22 79.3 0.0 5.7e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ABK73771.1 - 7.5e-10 39.3 0.0 1.5e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 ABK73771.1 - 9.8e-05 21.8 0.0 0.00019 20.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 ABK73771.1 - 0.00031 20.8 0.0 0.00053 20.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 ABK73771.1 - 0.00081 19.1 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 ABK73771.1 - 0.00089 19.3 0.6 0.0027 17.7 0.6 1.8 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 ABK73771.1 - 0.0019 18.1 0.3 0.0034 17.3 0.1 1.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 ABK73771.1 - 0.02 15.2 0.0 0.049 13.9 0.0 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 ABK73771.1 - 0.036 14.5 0.0 0.073 13.5 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ADH_zinc_N PF00107.26 ABK73771.1 - 0.13 12.3 0.5 0.41 10.6 0.2 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Epimerase PF01370.21 ABK73771.1 - 0.15 11.5 0.0 0.35 10.3 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DNA_pol3_alpha PF07733.12 ABK73772.1 - 5.6e-79 265.4 0.0 1.2e-78 264.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha NTPase domain DNA_pol3_finger PF17657.1 ABK73772.1 - 7.3e-60 201.1 0.0 1.6e-59 200.0 0.0 1.6 2 0 0 2 2 2 1 Bacterial DNA polymerase III alpha subunit finger domain PHP PF02811.19 ABK73772.1 - 3.3e-31 108.8 0.0 5.8e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 PHP domain HHH_6 PF14579.6 ABK73772.1 - 3.1e-25 88.2 0.0 1.1e-24 86.4 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_3 PF12836.7 ABK73772.1 - 0.0001 22.5 0.0 0.00033 20.9 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif tRNA_anti-codon PF01336.25 ABK73772.1 - 0.00023 21.1 0.1 0.0037 17.2 0.0 2.4 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain MeaB PF03308.16 ABK73773.1 - 2.6e-117 390.5 3.3 3.1e-117 390.3 3.3 1.0 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 ABK73773.1 - 5e-07 29.5 1.4 4.1e-06 26.5 1.4 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.23 ABK73773.1 - 4.8e-05 23.4 0.0 0.00013 22.0 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 ABK73773.1 - 0.00047 19.9 2.7 0.00065 19.5 1.2 2.1 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.22 ABK73773.1 - 0.00074 19.2 0.4 0.0044 16.7 0.4 2.2 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.18 ABK73773.1 - 0.00082 18.8 1.0 0.077 12.3 0.2 2.2 1 1 0 2 2 2 1 FtsK/SpoIIIE family IstB_IS21 PF01695.17 ABK73773.1 - 0.00085 19.1 0.0 0.0045 16.7 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ATP_bind_1 PF03029.17 ABK73773.1 - 0.0011 18.8 0.1 0.005 16.6 0.1 1.9 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 ABK73773.1 - 0.0011 19.4 1.1 0.0047 17.5 0.3 2.3 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 ABK73773.1 - 0.0016 18.2 0.0 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 Thymidylate kinase AAA_22 PF13401.6 ABK73773.1 - 0.0016 18.7 0.1 0.01 16.1 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ABK73773.1 - 0.0025 18.2 0.1 0.0054 17.1 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain ArsA_ATPase PF02374.15 ABK73773.1 - 0.003 16.8 0.2 0.0063 15.7 0.2 1.5 1 0 0 1 1 1 1 Anion-transporting ATPase Fer4_NifH PF00142.18 ABK73773.1 - 0.0039 16.7 0.0 0.0073 15.8 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_31 PF13614.6 ABK73773.1 - 0.0067 16.4 0.6 0.025 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 ABK73773.1 - 0.0075 16.3 0.6 0.046 13.8 0.6 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase NTPase_1 PF03266.15 ABK73773.1 - 0.0098 15.8 0.2 0.021 14.8 0.2 1.6 1 0 0 1 1 1 1 NTPase DUF87 PF01935.17 ABK73773.1 - 0.013 15.6 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain Glyco_trans_4_4 PF13579.6 ABK73773.1 - 0.017 15.6 4.2 0.07 13.6 4.0 2.4 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain AAA_24 PF13479.6 ABK73773.1 - 0.017 14.9 0.0 0.045 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 ABK73773.1 - 0.037 14.4 0.8 0.062 13.6 0.8 1.6 1 1 0 1 1 1 0 AAA domain Glyco_transf_4 PF13439.6 ABK73773.1 - 0.051 13.6 1.0 5 7.1 0.0 2.3 1 1 0 2 2 2 0 Glycosyltransferase Family 4 ParA PF10609.9 ABK73773.1 - 0.072 12.5 0.3 0.072 12.5 0.3 1.7 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase TrwB_AAD_bind PF10412.9 ABK73773.1 - 0.1 11.5 0.1 0.17 10.7 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain GTP_EFTU PF00009.27 ABK73773.1 - 0.14 11.7 0.1 5.4 6.5 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain KTI12 PF08433.10 ABK73773.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_10 PF12846.7 ABK73773.1 - 0.15 11.0 0.0 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_28 PF13521.6 ABK73773.1 - 0.15 12.3 0.2 0.15 12.3 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 ABK73773.1 - 0.19 11.5 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Hpr_kinase_C PF07475.12 ABK73773.1 - 0.32 10.5 3.4 5.3 6.5 0.2 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain DUF4242 PF14026.6 ABK73774.1 - 1.3e-21 76.5 0.1 7.7e-21 74.1 0.0 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF4242) Acetyltransf_1 PF00583.25 ABK73775.1 - 2.9e-07 30.7 0.0 4.4e-07 30.1 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ABK73775.1 - 4.4e-05 23.4 0.0 6.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ABK73775.1 - 0.00014 22.2 0.0 0.00024 21.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ABK73775.1 - 0.0006 19.9 0.0 0.0031 17.6 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain AMP-binding PF00501.28 ABK73777.1 - 2.1e-28 99.1 0.2 5.2e-14 51.7 0.1 2.3 2 1 0 2 2 2 2 AMP-binding enzyme Abhydrolase_6 PF12697.7 ABK73777.1 - 1.3e-08 35.8 4.3 1.3e-08 35.8 4.3 3.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family PHB_depo_C PF06850.11 ABK73777.1 - 0.00018 21.1 0.0 0.00033 20.2 0.0 1.5 1 1 0 1 1 1 1 PHB de-polymerase C-terminus Thioesterase PF00975.20 ABK73777.1 - 0.00052 20.2 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain DLH PF01738.18 ABK73777.1 - 0.0017 17.9 0.0 0.43 10.1 0.0 2.5 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 ABK73777.1 - 0.0039 16.9 0.0 0.0078 15.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 ABK73777.1 - 0.018 14.8 0.0 0.31 10.8 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Palm_thioest PF02089.15 ABK73777.1 - 0.038 13.8 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF4193 PF13834.6 ABK73778.1 - 3.5e-37 126.8 4.2 3.9e-37 126.7 4.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4193) tRNA-synt_2 PF00152.20 ABK73779.1 - 1e-67 228.5 0.0 1.3e-67 228.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ABK73779.1 - 2.9e-10 40.0 0.1 5.9e-10 39.0 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 ABK73779.1 - 0.0003 20.3 0.2 0.028 13.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) HdeA PF06411.11 ABK73780.1 - 0.013 15.7 0.9 0.025 14.8 0.9 1.5 1 1 0 1 1 1 0 HdeA/HdeB family ACT PF01842.25 ABK73781.1 - 0.00025 20.8 0.0 0.0005 19.8 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 ABK73781.1 - 0.18 12.4 0.0 0.35 11.5 0.0 1.4 1 0 0 1 1 1 0 ACT domain FCD PF07729.12 ABK73782.1 - 1.4e-23 83.7 8.3 1.4e-23 83.7 8.3 1.9 2 0 0 2 2 2 1 FCD domain GntR PF00392.21 ABK73782.1 - 1.9e-12 46.7 0.8 4.3e-12 45.5 0.1 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 ABK73782.1 - 0.005 16.4 0.0 0.005 16.4 0.0 2.5 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 ABK73782.1 - 0.0051 16.7 0.3 0.051 13.5 0.0 2.6 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 ABK73782.1 - 0.0065 16.9 0.2 0.037 14.5 0.0 2.3 2 1 1 3 3 3 1 Winged helix DNA-binding domain TFIIE_alpha PF02002.17 ABK73782.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 0 TFIIE alpha subunit Rrf2 PF02082.20 ABK73782.1 - 0.036 14.4 0.0 0.079 13.3 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator DUF480 PF04337.12 ABK73782.1 - 0.052 13.6 0.4 0.098 12.8 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF480 HTH_41 PF14502.6 ABK73782.1 - 0.092 12.5 0.3 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_9 PF08221.11 ABK73782.1 - 0.19 11.9 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Met_synt_B12 PF02965.17 ABK73783.1 - 4.6e-127 423.2 0.0 7e-127 422.5 0.0 1.3 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 ABK73783.1 - 1.3e-78 264.6 0.0 2.1e-78 263.8 0.0 1.4 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 ABK73783.1 - 1.4e-59 201.7 0.9 8.9e-59 199.1 0.1 2.5 3 0 0 3 3 3 1 Pterin binding enzyme B12-binding_2 PF02607.17 ABK73783.1 - 8.6e-25 87.0 1.8 5.6e-24 84.4 0.2 2.7 2 0 0 2 2 2 1 B12 binding domain B12-binding PF02310.19 ABK73783.1 - 1.5e-19 70.2 1.4 1.5e-18 67.0 0.4 3.0 3 0 0 3 3 3 1 B12 binding domain CdhD PF03599.16 ABK73783.1 - 0.00033 19.5 0.1 0.0016 17.3 0.0 2.0 2 0 0 2 2 2 1 CO dehydrogenase/acetyl-CoA synthase delta subunit rve_3 PF13683.6 ABK73783.1 - 0.035 13.9 0.2 0.98 9.2 0.1 2.7 2 0 0 2 2 2 0 Integrase core domain ComA PF02679.15 ABK73783.1 - 0.26 10.7 0.7 2.9 7.3 0.0 2.7 2 1 0 3 3 3 0 (2R)-phospho-3-sulfolactate synthase (ComA) IDEAL PF08858.10 ABK73784.1 - 0.16 11.7 0.9 0.24 11.2 0.9 1.2 1 0 0 1 1 1 0 IDEAL domain Peptidase_M20 PF01546.28 ABK73785.1 - 2.5e-37 128.6 0.0 1e-35 123.3 0.0 2.5 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ABK73785.1 - 2.3e-14 53.2 0.0 4.9e-14 52.2 0.0 1.6 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 ABK73785.1 - 6.2e-10 39.1 0.0 5.1e-09 36.1 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M28 MaoC_dehydratas PF01575.19 ABK73786.1 - 3.4e-22 78.3 0.0 4.6e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 ABK73786.1 - 0.14 12.3 0.0 0.16 12.1 0.0 1.4 1 1 0 1 1 1 0 N-terminal half of MaoC dehydratase ABC_tran PF00005.27 ABK73787.1 - 4.4e-22 79.1 0.0 7.2e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 ABK73787.1 - 3.5e-15 56.4 1.9 4.3e-15 56.1 1.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.6 ABK73787.1 - 4.1e-10 40.0 0.0 1.9e-06 27.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK73787.1 - 9.9e-06 25.1 0.0 0.012 15.0 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ABK73787.1 - 4.2e-05 23.2 0.0 0.00011 21.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 ABK73787.1 - 4.3e-05 23.3 1.0 0.0082 15.9 0.1 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ABK73787.1 - 0.00014 21.9 0.0 0.00024 21.0 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 ABK73787.1 - 0.00019 22.0 0.0 0.00031 21.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ABK73787.1 - 0.00088 19.7 0.1 0.0035 17.8 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 ABK73787.1 - 0.0071 15.9 1.0 0.084 12.4 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 ABK73787.1 - 0.016 15.0 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 ABK73787.1 - 0.016 15.5 0.1 0.048 13.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ABK73787.1 - 0.023 14.6 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_ATPase PF09818.9 ABK73787.1 - 0.049 12.4 2.1 0.32 9.7 0.1 2.6 2 1 0 2 2 2 0 Predicted ATPase of the ABC class NTPase_1 PF03266.15 ABK73787.1 - 0.055 13.4 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 NTPase cobW PF02492.19 ABK73787.1 - 0.056 13.0 0.2 0.09 12.4 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 ABK73787.1 - 0.083 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_27 PF13514.6 ABK73787.1 - 0.18 11.4 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 ABK73787.1 - 0.2 11.7 0.0 0.39 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain YitT_membrane PF02588.15 ABK73788.1 - 0.0094 15.3 10.7 0.035 13.5 1.3 2.1 2 0 0 2 2 2 2 Uncharacterised 5xTM membrane BCR, YitT family COG1284 Thump_like PF18096.1 ABK73789.1 - 1.2e-22 79.6 0.5 3.6e-22 78.1 0.2 2.0 2 0 0 2 2 2 1 THUMP domain-like DUF3253 PF11625.8 ABK73789.1 - 0.066 13.5 0.4 0.3 11.4 0.4 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) TPR_2 PF07719.17 ABK73790.1 - 1.1e-14 53.3 8.2 0.00013 21.8 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 ABK73790.1 - 1.6e-11 43.7 1.2 0.021 14.5 0.0 4.7 4 0 0 4 4 4 4 TPR repeat TPR_1 PF00515.28 ABK73790.1 - 1.3e-09 37.5 2.2 0.011 15.6 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 ABK73790.1 - 5.2e-06 26.7 14.4 0.0023 18.2 1.0 5.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 ABK73790.1 - 5.6e-05 23.0 0.0 28 5.3 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 ABK73790.1 - 0.00027 21.4 12.0 0.024 15.1 0.2 5.8 5 3 1 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 ABK73790.1 - 0.0023 18.2 3.2 39 4.9 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 ABK73790.1 - 0.004 17.9 20.8 0.39 11.7 0.1 7.2 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 ABK73790.1 - 0.17 12.0 9.2 9.2 6.6 0.2 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 ABK73790.1 - 2.4 8.1 13.2 9.7 6.2 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 ABK73790.1 - 3.5 8.3 31.4 3.4 8.4 0.7 6.5 8 0 0 8 8 7 0 Tetratricopeptide repeat Cupin_1 PF00190.22 ABK73791.1 - 1.6e-37 128.4 0.0 4.2e-19 68.6 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 ABK73791.1 - 2.3e-24 84.9 1.2 5.8e-13 48.4 0.0 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 ABK73791.1 - 1.6e-07 31.3 0.2 0.00046 20.1 0.1 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Ectoine_synth PF06339.12 ABK73791.1 - 4.5e-05 23.7 0.0 0.026 14.7 0.0 2.4 2 0 0 2 2 2 2 Ectoine synthase MannoseP_isomer PF01050.18 ABK73791.1 - 0.00022 21.1 0.0 0.0016 18.3 0.0 1.9 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase Cupin_6 PF12852.7 ABK73791.1 - 0.0015 18.3 0.2 0.4 10.4 0.0 2.2 2 0 0 2 2 2 2 Cupin GCD14_N PF14801.6 ABK73791.1 - 0.0023 17.7 0.0 0.038 13.8 0.0 2.2 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit N-term ARD PF03079.14 ABK73791.1 - 0.0056 16.9 0.1 3.1 8.0 0.0 2.1 2 0 0 2 2 2 2 ARD/ARD' family CENP-C_C PF11699.8 ABK73791.1 - 0.0079 16.4 0.0 0.2 11.9 0.0 2.2 2 0 0 2 2 2 1 Mif2/CENP-C like FdtA PF05523.11 ABK73791.1 - 0.059 13.1 0.0 0.16 11.7 0.0 1.6 2 0 0 2 2 2 0 WxcM-like, C-terminal Cupin_3 PF05899.12 ABK73791.1 - 0.076 12.7 0.0 8.7 6.1 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF861) Cupin_8 PF13621.6 ABK73791.1 - 0.15 11.7 0.1 8.3 6.0 0.2 2.1 2 0 0 2 2 2 0 Cupin-like domain Cupin_4 PF08007.12 ABK73791.1 - 0.19 11.2 0.1 0.29 10.6 0.1 1.2 1 0 0 1 1 1 0 Cupin superfamily protein Ribosomal_S14 PF00253.21 ABK73792.1 - 9.9e-26 89.3 0.5 1.6e-25 88.6 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e HTH_17 PF12728.7 ABK73792.1 - 0.0041 17.3 0.8 0.0077 16.4 0.1 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain DUF3043 PF11241.8 ABK73792.1 - 0.29 11.2 6.9 0.42 10.6 6.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) GFO_IDH_MocA PF01408.22 ABK73793.1 - 9.2e-18 65.2 0.0 1.3e-17 64.7 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 ABK73793.1 - 0.0023 18.5 0.0 0.0048 17.4 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 ABK73793.1 - 0.08 13.0 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA_C PF02894.17 ABK73793.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain ABM PF03992.16 ABK73794.1 - 1.4e-08 34.7 0.3 1.7e-08 34.4 0.3 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase CobS_N PF12556.8 ABK73794.1 - 0.015 15.0 0.1 0.028 14.1 0.1 1.4 1 0 0 1 1 1 0 Cobaltochelatase CobS subunit N terminal TruB_N PF01509.18 ABK73794.1 - 0.094 13.1 0.0 0.11 12.9 0.0 1.1 1 0 0 1 1 1 0 TruB family pseudouridylate synthase (N terminal domain) DUF982 PF06169.12 ABK73794.1 - 0.16 12.0 1.7 2.5 8.2 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF982) Peptidase_S9 PF00326.21 ABK73795.1 - 2.1e-48 164.6 0.2 3.2e-48 164.0 0.2 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 ABK73795.1 - 6.6e-29 100.9 0.0 1.1e-27 97.0 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Hydrolase_4 PF12146.8 ABK73795.1 - 0.0029 16.9 0.2 0.24 10.6 0.1 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 ABK73795.1 - 0.038 14.1 0.0 0.087 13.0 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein cNMP_binding PF00027.29 ABK73796.1 - 1.9e-24 85.5 0.0 3.1e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 ABK73796.1 - 3.5e-18 65.3 0.8 3.5e-18 65.3 0.8 1.7 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain Crp PF00325.20 ABK73796.1 - 2.7e-06 26.9 0.0 5.5e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, crp family GntR PF00392.21 ABK73796.1 - 3e-05 23.6 0.2 9.4e-05 22.0 0.1 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family Sigma70_r4 PF04545.16 ABK73796.1 - 9.9e-05 21.8 0.0 0.00024 20.6 0.0 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_24 PF13412.6 ABK73796.1 - 0.00012 21.5 0.0 0.00034 20.1 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 ABK73796.1 - 0.00025 20.9 1.8 0.00083 19.2 0.1 2.4 3 0 0 3 3 3 1 MarR family HTH_3 PF01381.22 ABK73796.1 - 0.00049 20.1 0.0 0.014 15.4 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix TrmB PF01978.19 ABK73796.1 - 0.0041 17.0 0.0 0.0078 16.1 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_36 PF13730.6 ABK73796.1 - 0.0048 16.8 0.0 0.0083 16.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Rrf2 PF02082.20 ABK73796.1 - 0.0096 16.3 0.3 0.15 12.4 0.0 2.4 2 0 0 2 2 2 1 Transcriptional regulator HTH_29 PF13551.6 ABK73796.1 - 0.01 15.8 0.3 0.038 14.0 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn helix HTH_31 PF13560.6 ABK73796.1 - 0.011 16.1 1.3 0.18 12.2 0.4 3.0 2 1 0 2 2 2 0 Helix-turn-helix domain MarR PF01047.22 ABK73796.1 - 0.019 14.9 0.0 0.097 12.6 0.0 2.1 3 0 0 3 3 3 0 MarR family Sigma70_r4_2 PF08281.12 ABK73796.1 - 0.02 14.5 0.2 0.067 12.9 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_23 PF13384.6 ABK73796.1 - 0.034 13.9 0.4 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain HTH_28 PF13518.6 ABK73796.1 - 0.066 13.3 0.3 0.24 11.5 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain DUF2666 PF10869.8 ABK73796.1 - 0.09 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2666) Phage_min_cap2 PF06152.11 ABK73796.1 - 0.12 11.2 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Phage minor capsid protein 2 HTH_AsnC-type PF13404.6 ABK73796.1 - 0.15 11.9 3.5 0.47 10.3 0.1 2.9 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain HTH_IclR PF09339.10 ABK73796.1 - 0.31 10.9 2.0 0.89 9.4 0.0 2.7 4 0 0 4 4 4 0 IclR helix-turn-helix domain 4HBT_3 PF13622.6 ABK73797.1 - 2.5e-19 70.5 2.3 3.9e-19 69.9 2.3 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily ArAE_2 PF10334.9 ABK73797.1 - 0.092 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Aromatic acid exporter family member 2 MlaD PF02470.20 ABK73798.1 - 1.9e-13 50.5 0.0 3.3e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 MlaD protein Mce4_CUP1 PF11887.8 ABK73798.1 - 1.3e-07 31.3 1.4 2.5e-07 30.4 1.4 1.4 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative CorA PF01544.18 ABK73798.1 - 0.00016 21.1 0.8 0.014 14.7 0.1 2.1 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 ABK73798.1 - 0.0002 21.4 3.4 0.00029 20.9 1.1 2.3 2 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Vps5 PF09325.10 ABK73798.1 - 0.0099 15.4 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 1 Vps5 C terminal like Cucumopine_C PF18631.1 ABK73798.1 - 0.024 14.6 0.1 0.61 10.0 0.0 2.5 2 1 1 3 3 3 0 Cucumopine synthase C-terminal helical bundle domain DUF5595 PF18077.1 ABK73798.1 - 0.037 14.1 0.4 0.069 13.2 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) PAC2 PF09754.9 ABK73799.1 - 1.2e-45 156.2 0.2 1.5e-45 155.9 0.2 1.1 1 0 0 1 1 1 1 PAC2 family Rnk_N PF14760.6 ABK73799.1 - 3.2 8.3 6.7 2.3 8.8 0.1 3.1 3 0 0 3 3 3 0 Rnk N-terminus HxlR PF01638.17 ABK73800.1 - 2.1e-15 56.4 0.0 2.6e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix MarR_2 PF12802.7 ABK73800.1 - 6.1e-06 26.0 0.0 1.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 ABK73800.1 - 0.00028 21.3 0.0 0.00044 20.7 0.0 1.4 1 1 0 1 1 1 1 Winged helix DNA-binding domain PadR PF03551.14 ABK73800.1 - 0.002 18.1 0.0 0.0028 17.6 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family MarR PF01047.22 ABK73800.1 - 0.0029 17.5 0.0 0.0048 16.8 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 ABK73800.1 - 0.013 15.6 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_IclR PF09339.10 ABK73800.1 - 0.033 14.0 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_24 PF13412.6 ABK73800.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Replic_Relax PF13814.6 ABK73800.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.5 1 1 0 1 1 1 0 Replication-relaxation NMO PF03060.15 ABK73801.1 - 1.5e-54 185.6 3.7 1.9e-52 178.7 3.7 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 ABK73801.1 - 6e-10 38.6 0.2 9.6e-05 21.5 0.2 2.3 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 ABK73801.1 - 2e-05 23.8 2.4 6.4e-05 22.1 2.8 1.6 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 ABK73801.1 - 0.018 14.2 0.7 0.034 13.3 0.7 1.5 1 1 0 1 1 1 0 Conserved region in glutamate synthase TMP-TENI PF02581.17 ABK73801.1 - 0.027 13.8 0.0 0.056 12.8 0.0 1.5 1 0 0 1 1 1 0 Thiamine monophosphate synthase DUF3969 PF13108.6 ABK73801.1 - 0.078 13.0 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3969) RrnaAD PF00398.20 ABK73802.1 - 2.6e-30 105.4 0.0 3.2e-30 105.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.14 ABK73802.1 - 0.00025 20.7 0.0 0.00039 20.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 ABK73802.1 - 0.0019 18.8 0.0 0.0036 18.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 ABK73802.1 - 0.21 11.2 0.0 0.34 10.5 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) adh_short_C2 PF13561.6 ABK73803.1 - 1.3e-53 182.0 0.5 1.5e-53 181.7 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK73803.1 - 9.4e-46 155.7 0.0 1.1e-45 155.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK73803.1 - 6.5e-07 29.4 0.2 1.1e-06 28.7 0.2 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK73803.1 - 0.1 12.1 0.6 0.67 9.4 0.6 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_deac_1 PF01522.21 ABK73804.1 - 2.4e-20 72.7 0.0 5.1e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase ABC_tran PF00005.27 ABK73805.1 - 6e-37 127.2 0.0 7.9e-37 126.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK73805.1 - 7.1e-11 42.5 0.0 2.8e-05 24.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK73805.1 - 2.9e-07 30.1 0.2 1.9e-06 27.5 0.2 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ABK73805.1 - 4.8e-05 23.7 0.1 0.074 13.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 ABK73805.1 - 0.00039 20.1 0.0 0.00078 19.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 ABK73805.1 - 0.0012 19.2 0.1 0.0022 18.4 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 ABK73805.1 - 0.0014 18.1 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 2 Bacterial TniB protein AAA PF00004.29 ABK73805.1 - 0.0021 18.5 0.1 0.19 12.1 0.0 2.4 1 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.6 ABK73805.1 - 0.0029 16.3 0.0 0.35 9.4 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_15 PF13175.6 ABK73805.1 - 0.014 15.2 0.0 0.16 11.7 0.0 2.0 1 1 1 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 ABK73805.1 - 0.017 14.2 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 ABK73805.1 - 0.017 15.3 0.1 0.041 14.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ABK73805.1 - 0.018 15.6 0.0 0.028 14.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 ABK73805.1 - 0.019 14.3 0.1 0.078 12.4 0.0 1.9 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 ABK73805.1 - 0.023 14.9 0.0 0.054 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ABK73805.1 - 0.024 14.4 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ABK73805.1 - 0.04 14.5 0.0 0.08 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA12 PF10443.9 ABK73805.1 - 0.041 12.6 0.0 0.057 12.1 0.0 1.1 1 0 0 1 1 1 0 RNA12 protein RsgA_GTPase PF03193.16 ABK73805.1 - 0.047 13.6 0.1 0.11 12.5 0.0 1.7 2 0 0 2 2 1 0 RsgA GTPase AAA_30 PF13604.6 ABK73805.1 - 0.053 13.2 0.4 0.25 11.0 0.0 2.1 2 1 1 3 3 3 0 AAA domain Roc PF08477.13 ABK73805.1 - 0.057 13.6 0.0 0.092 13.0 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 ABK73805.1 - 0.059 13.7 0.4 0.52 10.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 ABK73805.1 - 0.074 12.7 0.1 0.11 12.1 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_ATPase PF09818.9 ABK73805.1 - 0.13 11.1 0.2 1.6 7.5 0.0 2.5 2 1 0 2 2 2 0 Predicted ATPase of the ABC class SbcCD_C PF13558.6 ABK73805.1 - 0.13 12.6 0.1 2.1 8.7 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 ABK73805.1 - 0.14 12.1 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 ABK73805.1 - 0.16 11.5 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 ABK73805.1 - 0.18 11.4 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 ABK73805.1 - 0.22 11.5 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain G-alpha PF00503.20 ABK73805.1 - 0.22 10.6 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit GerE PF00196.19 ABK73806.1 - 1e-18 66.6 0.5 1.9e-18 65.8 0.5 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family GAF PF01590.26 ABK73806.1 - 1e-07 32.7 0.4 3e-07 31.2 0.1 1.8 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.6 ABK73806.1 - 1.3e-07 32.0 0.0 4.2e-07 30.3 0.0 1.9 1 0 0 1 1 1 1 GAF domain Sigma70_r4_2 PF08281.12 ABK73806.1 - 1.5e-06 27.8 0.1 3.2e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 ABK73806.1 - 7.5e-06 25.4 0.5 1.8e-05 24.1 0.5 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 TerB_C PF15615.6 ABK73806.1 - 0.017 15.4 0.2 0.032 14.6 0.2 1.4 1 0 0 1 1 1 0 TerB-C domain KORA PF16509.5 ABK73806.1 - 0.11 12.8 0.2 0.27 11.5 0.2 1.6 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor HTH_40 PF14493.6 ABK73806.1 - 0.12 12.9 0.1 0.24 11.9 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Peripla_BP_2 PF01497.18 ABK73807.1 - 4.6e-21 75.5 0.2 6.2e-21 75.0 0.2 1.2 1 0 0 1 1 1 1 Periplasmic binding protein LPAM_2 PF13627.6 ABK73807.1 - 0.3 11.0 4.0 0.8 9.6 4.0 1.8 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site ECH_1 PF00378.20 ABK73808.1 - 2e-38 132.1 0.0 2.3e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK73808.1 - 2.7e-18 66.6 0.0 3.6e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase CSTF_C PF14304.6 ABK73809.1 - 0.018 14.6 0.3 0.5 10.0 0.0 2.3 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal DUF732 PF05305.14 ABK73810.1 - 7.6e-19 67.9 1.7 8.7e-19 67.7 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF732) Beta-lactamase PF00144.24 ABK73811.1 - 1e-65 222.2 2.4 1.2e-65 221.9 2.4 1.0 1 0 0 1 1 1 1 Beta-lactamase Peptidase_M23 PF01551.22 ABK73812.1 - 3.2e-31 107.4 0.6 3.2e-31 107.4 0.6 2.2 2 0 0 2 2 2 1 Peptidase family M23 Biotin_lipoyl PF00364.22 ABK73812.1 - 0.044 13.6 0.1 0.15 11.9 0.0 1.9 2 0 0 2 2 2 0 Biotin-requiring enzyme RnfC_N PF13375.6 ABK73812.1 - 0.35 10.8 2.1 5.2 7.1 0.0 2.8 3 0 0 3 3 3 0 RnfC Barrel sandwich hybrid domain DUF417 PF04224.12 ABK73813.1 - 2.4e-25 89.1 8.0 1.7e-23 83.0 8.0 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF417 Bac_luciferase PF00296.20 ABK73814.1 - 4.9e-80 269.3 10.2 5.5e-80 269.1 10.2 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase SecD_SecF PF02355.16 ABK73815.1 - 4.1e-08 32.8 8.7 6.7e-08 32.1 8.7 1.3 1 0 0 1 1 1 1 Protein export membrane protein Sec_GG PF07549.14 ABK73815.1 - 0.00022 20.6 0.0 0.00052 19.4 0.0 1.6 1 0 0 1 1 1 1 SecD/SecF GG Motif MMPL PF03176.15 ABK73815.1 - 0.0004 19.4 17.5 0.00083 18.4 17.5 1.5 1 0 0 1 1 1 1 MMPL family Collagen PF01391.18 ABK73815.1 - 0.0028 17.4 21.9 0.0028 17.4 21.9 2.3 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) ACR_tran PF00873.19 ABK73815.1 - 0.43 8.2 10.5 0.27 8.8 7.1 1.9 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family Pyr_redox_2 PF07992.14 ABK73816.1 - 1.7e-44 152.3 0.8 2.3e-44 151.8 0.8 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ABK73816.1 - 2.2e-20 72.9 0.0 4.6e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 ABK73816.1 - 3.6e-18 65.9 3.6 4.1e-14 52.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ABK73816.1 - 5.5e-12 45.6 0.4 1.4e-07 31.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ABK73816.1 - 5.6e-07 29.4 17.6 0.0002 21.0 5.5 3.4 2 1 1 3 3 3 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ABK73816.1 - 1.3e-06 28.1 1.4 4.9e-06 26.1 1.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 ABK73816.1 - 2.7e-06 26.7 2.3 2.8e-06 26.7 0.8 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 ABK73816.1 - 7.2e-06 25.4 0.2 1.9e-05 24.1 0.2 1.6 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 ABK73816.1 - 0.00062 19.0 6.1 0.00062 19.0 6.1 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 ABK73816.1 - 0.00077 18.3 3.9 0.081 11.6 3.6 2.3 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 ABK73816.1 - 0.0023 18.1 1.9 0.0023 18.1 1.9 2.7 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ABK73816.1 - 0.006 16.6 7.0 0.75 9.8 0.3 4.1 4 0 0 4 4 4 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 ABK73816.1 - 0.0063 15.8 3.9 0.1 11.8 2.5 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 ABK73816.1 - 0.059 12.6 4.3 2.8 7.1 0.5 2.7 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Ribosomal_S11 PF00411.19 ABK73816.1 - 0.13 12.7 1.7 0.79 10.2 0.6 2.3 2 0 0 2 2 2 0 Ribosomal protein S11 Lycopene_cycl PF05834.12 ABK73816.1 - 0.14 11.2 3.2 0.25 10.3 3.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 ABK73816.1 - 0.29 10.3 9.5 0.029 13.6 2.3 2.3 2 0 0 2 2 2 0 FAD binding domain K_oxygenase PF13434.6 ABK73816.1 - 0.44 9.6 2.9 0.3 10.2 0.1 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 ABK73816.1 - 0.88 10.0 2.5 1.6 9.2 0.3 2.5 2 1 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 ABK73816.1 - 4.7 7.0 5.1 17 5.2 2.6 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1232 PF06803.12 ABK73817.1 - 1.1e-13 50.7 8.1 1.1e-13 50.7 8.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1232) DUF4381 PF14316.6 ABK73817.1 - 0.084 13.1 3.9 0.14 12.4 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Rhodanese PF00581.20 ABK73818.1 - 4.1e-29 101.3 0.1 2.1e-06 28.2 0.0 4.5 4 0 0 4 4 4 4 Rhodanese-like domain COesterase PF00135.28 ABK73819.1 - 6.8e-89 299.1 0.0 1.6e-88 297.8 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ABK73819.1 - 5.7e-10 39.4 1.8 7.3e-09 35.8 1.8 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ABK73819.1 - 7.4e-05 22.3 0.0 0.00014 21.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 ABK73819.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative esterase p450 PF00067.22 ABK73820.1 - 3.6e-36 124.9 0.0 2.9e-26 92.2 0.1 3.1 1 1 0 2 2 2 2 Cytochrome P450 UDPGT PF00201.18 ABK73821.1 - 2.4e-12 46.4 0.0 3.6e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 ABK73821.1 - 2.1e-05 24.5 0.0 3.2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain PSK_trans_fac PF07704.11 ABK73821.1 - 0.081 13.7 4.1 1.7 9.5 0.6 2.8 2 0 0 2 2 2 0 Rv0623-like transcription factor EamA PF00892.20 ABK73822.1 - 6.8e-27 94.3 32.3 5.7e-15 55.7 12.1 2.1 2 0 0 2 2 2 2 EamA-like transporter family Abhydrolase_6 PF12697.7 ABK73823.1 - 1.2e-17 65.2 5.0 1.8e-17 64.7 5.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ABK73823.1 - 5.4e-12 45.9 0.1 6.7e-12 45.6 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ABK73823.1 - 6.5e-09 35.4 0.1 8.9e-09 35.0 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 ABK73823.1 - 3.9e-07 30.4 0.0 5.9e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.25 ABK73823.1 - 4.6e-05 23.3 0.0 0.00016 21.6 0.0 1.7 1 1 1 2 2 2 1 Lipase (class 3) Abhydrolase_5 PF12695.7 ABK73823.1 - 0.0023 17.7 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 ABK73823.1 - 0.0032 17.2 0.0 0.0046 16.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Esterase_phd PF10503.9 ABK73823.1 - 0.0047 16.4 0.3 0.0071 15.9 0.3 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Esterase PF00756.20 ABK73823.1 - 0.0074 16.0 0.1 0.033 13.8 0.1 1.8 1 1 1 2 2 2 1 Putative esterase LIDHydrolase PF10230.9 ABK73823.1 - 0.01 15.4 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Chlorophyllase2 PF12740.7 ABK73823.1 - 0.045 12.7 0.0 0.064 12.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Pyr_redox_2 PF07992.14 ABK73823.1 - 0.056 12.7 0.0 0.19 11.0 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lipase PF00151.19 ABK73823.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipase TetR_N PF00440.23 ABK73824.1 - 9.6e-15 54.1 0.0 1.6e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 ABK73824.1 - 1.1e-12 48.3 9.3 1.1e-12 48.3 9.3 2.0 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain HTH_7 PF02796.15 ABK73824.1 - 0.019 15.0 0.1 0.047 13.8 0.1 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_Tnp_ISL3 PF13542.6 ABK73824.1 - 0.067 12.6 0.2 0.23 10.9 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_Tnp_1_2 PF13022.6 ABK73824.1 - 0.15 12.3 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase CCG PF02754.16 ABK73825.1 - 7e-34 115.9 1.8 3.2e-17 62.5 0.1 2.6 2 0 0 2 2 2 2 Cysteine-rich domain Fer4_8 PF13183.6 ABK73825.1 - 6.5e-13 48.9 2.5 2.6e-12 47.0 2.5 2.1 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 ABK73825.1 - 4.9e-09 36.6 2.2 0.0017 18.9 0.1 2.8 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 ABK73825.1 - 5e-09 36.2 3.8 5e-09 36.2 3.8 2.4 2 1 0 2 2 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 ABK73825.1 - 6.6e-09 35.8 7.8 6.6e-09 35.8 7.8 3.6 3 1 0 3 3 3 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 ABK73825.1 - 3.8e-07 30.6 2.2 0.022 15.3 0.1 2.7 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 ABK73825.1 - 1.2e-06 28.3 11.8 0.003 17.5 1.6 2.8 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4 PF00037.27 ABK73825.1 - 1.6e-06 27.7 13.4 0.0026 17.5 5.3 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 ABK73825.1 - 0.00072 20.4 9.8 0.16 12.9 0.5 3.1 3 0 0 3 3 2 2 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 ABK73825.1 - 0.0032 17.8 17.6 0.072 13.6 2.1 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_3 PF12798.7 ABK73825.1 - 0.0055 17.6 17.1 0.024 15.6 5.3 2.7 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.6 ABK73825.1 - 0.026 14.6 8.1 0.76 9.9 1.1 2.8 3 0 0 3 3 2 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 ABK73825.1 - 0.027 14.5 12.8 0.46 10.6 3.8 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 ABK73825.1 - 0.18 12.7 10.3 0.65 10.9 0.9 3.2 3 0 0 3 3 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 ABK73825.1 - 1.6 9.0 6.1 2 8.7 1.3 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 ABK73825.1 - 5.2 7.7 12.4 15 6.2 1.9 3.1 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4 PF00037.27 ABK73826.1 - 3.2e-08 33.0 12.1 1e-05 25.1 4.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 ABK73826.1 - 8.5e-08 32.3 10.1 1.2e-07 31.8 10.1 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 ABK73826.1 - 1.3e-07 32.1 36.5 1.3e-05 25.7 13.8 1.9 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 ABK73826.1 - 1e-06 28.5 13.8 0.00013 21.9 3.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 ABK73826.1 - 1e-06 28.7 10.0 1.5e-06 28.2 10.0 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 ABK73826.1 - 8.3e-06 26.6 7.6 0.0079 17.1 1.1 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 ABK73826.1 - 7.6e-05 22.9 12.7 0.0038 17.6 3.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 ABK73826.1 - 0.0001 22.4 14.2 0.002 18.2 14.3 2.1 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_13 PF13370.6 ABK73826.1 - 0.0017 18.8 14.4 0.034 14.7 14.4 2.2 1 1 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_2 PF12797.7 ABK73826.1 - 0.0024 17.9 3.6 0.0024 17.9 3.6 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_22 PF17179.4 ABK73826.1 - 0.012 16.4 3.2 1.2 10.0 0.8 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 ABK73826.1 - 0.017 15.7 13.7 0.34 11.5 2.4 2.2 1 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 ABK73826.1 - 0.018 15.3 14.2 0.95 9.7 14.1 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 ABK73826.1 - 0.03 15.1 13.5 10 6.9 13.5 2.5 1 1 0 1 1 1 0 4Fe-4S single cluster domain Fer4_8 PF13183.6 ABK73826.1 - 0.05 14.0 14.8 24 5.5 15.0 2.2 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 ABK73826.1 - 0.057 14.4 17.1 0.42 11.7 5.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain DUF3079 PF11278.8 ABK73826.1 - 1.4 8.8 8.8 0.29 11.0 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3079) ParD PF09386.10 ABK73827.1 - 0.035 14.5 0.9 0.04 14.3 0.9 1.1 1 0 0 1 1 1 0 Antitoxin ParD PSD2 PF07624.11 ABK73827.1 - 0.052 13.3 0.5 0.099 12.4 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1585) EF-1_beta_acid PF10587.9 ABK73827.1 - 0.57 10.7 8.6 2.2 8.8 1.9 2.4 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region Rhodanese PF00581.20 ABK73828.1 - 1.1e-25 90.2 0.0 7.7e-15 55.3 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain ketoacyl-synt PF00109.26 ABK73829.1 - 9.6e-192 634.7 2.5 6.1e-97 324.1 0.0 2.9 3 0 0 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 ABK73829.1 - 8.5e-116 384.2 1.6 5.6e-57 192.5 0.0 3.1 3 0 0 3 3 3 2 KR domain Acyl_transf_1 PF00698.21 ABK73829.1 - 5.3e-109 364.6 0.0 7.3e-55 186.7 0.1 2.3 2 0 0 2 2 2 2 Acyl transferase domain Ketoacyl-synt_C PF02801.22 ABK73829.1 - 2.1e-85 282.6 4.8 2.3e-42 143.7 0.4 2.7 2 0 0 2 2 2 2 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 ABK73829.1 - 1.6e-48 165.5 0.0 3.2e-48 164.5 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 ABK73829.1 - 6.1e-44 149.1 0.0 1.8e-21 76.7 0.0 2.6 2 0 0 2 2 2 2 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 ABK73829.1 - 1.5e-33 115.9 0.0 1.7e-18 66.8 0.0 3.6 3 0 0 3 3 3 2 short chain dehydrogenase PP-binding PF00550.25 ABK73829.1 - 6.4e-30 103.3 0.1 7.5e-17 61.5 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site adh_short_C2 PF13561.6 ABK73829.1 - 8.3e-26 91.0 7.4 3.5e-15 56.2 0.1 3.3 4 0 0 4 4 4 2 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N_2 PF13602.6 ABK73829.1 - 9.4e-23 81.7 0.1 3.3e-21 76.7 0.1 3.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ABK73829.1 - 1e-16 61.1 0.3 5.5e-16 58.7 0.1 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Thiolase_N PF00108.23 ABK73829.1 - 2.1e-14 53.6 3.8 2.6e-07 30.3 0.2 2.6 2 0 0 2 2 2 2 Thiolase, N-terminal domain GDP_Man_Dehyd PF16363.5 ABK73829.1 - 2.7e-10 40.2 0.0 1.9e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ABK73829.1 - 1.4e-08 34.5 0.3 0.0037 16.8 0.0 3.0 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ABK73829.1 - 1.2e-05 24.6 0.0 0.047 12.8 0.0 2.2 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein ADH_N PF08240.12 ABK73829.1 - 0.00012 21.9 0.0 0.00038 20.3 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SAT PF16073.5 ABK73829.1 - 0.00044 20.1 0.0 16 5.1 0.0 4.5 4 0 0 4 4 4 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Peptidase_S31 PF05578.12 ABK73829.1 - 0.016 14.7 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 Pestivirus NS3 polyprotein peptidase S31 Pyr_redox PF00070.27 ABK73829.1 - 0.094 13.3 1.2 4.3 8.0 0.1 3.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 ABK73829.1 - 0.11 11.8 1.2 11 5.3 0.5 2.5 2 0 0 2 2 2 0 ThiF family ApbA PF02558.16 ABK73829.1 - 0.13 11.9 0.6 24 4.5 0.0 2.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA ACP_syn_III PF08545.10 ABK73829.1 - 0.29 11.0 5.9 4.1 7.3 1.1 3.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 ABK73829.1 - 0.34 11.1 2.1 1.6 9.0 0.1 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Molybdopterin PF00384.22 ABK73830.1 - 3.5e-63 214.1 0.0 4.2e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 ABK73830.1 - 3.1e-27 94.8 0.0 8.4e-27 93.4 0.0 1.8 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 ABK73830.1 - 0.0053 16.7 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain Molybdopterin_N PF18364.1 ABK73830.1 - 0.16 12.0 1.2 1.5 8.9 0.1 3.0 3 0 0 3 3 3 0 Molybdopterin oxidoreductase N-terminal domain B12-binding PF02310.19 ABK73831.1 - 3e-19 69.2 0.1 3e-19 69.2 0.1 2.6 2 1 1 3 3 3 1 B12 binding domain B12-binding_2 PF02607.17 ABK73831.1 - 3.8e-09 36.9 3.4 5.2e-09 36.4 2.3 1.8 2 0 0 2 2 2 1 B12 binding domain DUF3145 PF11343.8 ABK73832.1 - 8.2e-71 236.6 0.6 9.3e-71 236.5 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3145) ABC_tran PF00005.27 ABK73833.1 - 4.3e-31 108.2 0.0 6.7e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter TOBE PF03459.17 ABK73833.1 - 6.8e-12 45.5 2.0 1.8e-11 44.2 0.4 2.6 2 1 1 3 3 3 1 TOBE domain AAA_21 PF13304.6 ABK73833.1 - 3.6e-10 40.2 0.8 0.00012 22.0 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ABK73833.1 - 0.00026 20.7 0.0 0.00071 19.3 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 ABK73833.1 - 0.00068 19.1 0.0 0.65 9.4 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ABK73833.1 - 0.0014 18.9 0.1 0.0075 16.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ABK73833.1 - 0.0016 18.8 3.4 0.0081 16.6 3.5 2.0 1 1 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.9 ABK73833.1 - 0.0052 15.6 1.1 1.9 7.2 0.1 2.9 2 1 0 2 2 2 2 Predicted ATPase of the ABC class AAA_30 PF13604.6 ABK73833.1 - 0.0069 16.1 0.6 0.0069 16.1 0.6 2.3 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 ABK73833.1 - 0.012 16.2 0.0 0.017 15.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain MukB PF04310.12 ABK73833.1 - 0.014 15.2 0.2 0.022 14.6 0.2 1.2 1 0 0 1 1 1 0 MukB N-terminal AAA_25 PF13481.6 ABK73833.1 - 0.014 15.0 1.6 0.3 10.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain TOBE_3 PF12857.7 ABK73833.1 - 0.016 15.1 0.1 0.042 13.8 0.1 1.8 1 0 0 1 1 1 0 TOBE-like domain SbcCD_C PF13558.6 ABK73833.1 - 0.027 14.7 0.2 0.3 11.3 0.2 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_27 PF13514.6 ABK73833.1 - 0.036 13.7 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ABK73833.1 - 0.053 13.8 0.0 0.15 12.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 ABK73833.1 - 0.067 13.1 0.2 0.36 10.7 0.0 2.0 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.15 ABK73833.1 - 0.12 12.2 0.4 0.34 10.8 0.1 1.8 2 0 0 2 2 2 0 NTPase RsgA_GTPase PF03193.16 ABK73833.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase rve PF00665.26 ABK73834.1 - 1.6e-12 47.6 0.2 1.3e-11 44.7 0.0 2.5 3 0 0 3 3 3 1 Integrase core domain HTH_38 PF13936.6 ABK73834.1 - 3.3e-05 23.5 0.0 6.8e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 ABK73834.1 - 0.0052 16.5 0.7 0.019 14.7 0.4 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 ABK73834.1 - 0.014 15.4 0.1 0.049 13.7 0.1 1.9 1 0 0 1 1 1 0 Winged helix-turn helix HTH_3 PF01381.22 ABK73834.1 - 0.015 15.3 0.0 0.035 14.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix HTH_35 PF13693.6 ABK73834.1 - 0.018 15.1 0.0 0.055 13.5 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_19 PF12844.7 ABK73834.1 - 0.022 14.7 0.0 0.049 13.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_31 PF13560.6 ABK73834.1 - 0.023 15.0 6.7 0.023 15.0 0.3 3.8 3 1 0 3 3 3 0 Helix-turn-helix domain HTH_39 PF14090.6 ABK73834.1 - 0.16 11.8 0.6 1.7 8.4 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Thiolase_N PF00108.23 ABK73835.1 - 5.6e-13 48.9 1.0 3.6e-12 46.2 0.0 2.6 3 1 0 3 3 3 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ABK73835.1 - 3.5e-10 39.6 0.3 8.5e-10 38.4 0.1 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ABK73835.1 - 0.095 12.3 3.2 0.17 11.4 0.7 2.5 2 1 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Haem_degrading PF03928.14 ABK73835.1 - 2 8.5 5.0 19 5.3 0.2 2.5 2 1 0 2 2 2 0 Haem-degrading CN_hydrolase PF00795.22 ABK73836.1 - 5.3e-45 153.8 0.0 6.5e-45 153.5 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Fer2 PF00111.27 ABK73837.1 - 9.2e-11 41.5 1.2 1.7e-10 40.7 1.2 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.21 ABK73837.1 - 4.6e-06 27.2 0.0 1.8e-05 25.3 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 ABK73837.1 - 0.00017 21.9 0.0 0.00028 21.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Fer2_4 PF13510.6 ABK73837.1 - 0.0029 17.6 0.2 0.0059 16.6 0.2 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_6 PF08030.12 ABK73837.1 - 0.012 15.8 0.1 0.022 14.9 0.1 1.4 1 0 0 1 1 1 0 Ferric reductase NAD binding domain RNase_HII PF01351.18 ABK73838.1 - 4.7e-43 147.3 0.0 5.9e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII Fe-ADH PF00465.19 ABK73839.1 - 1.2e-114 383.0 0.2 1.5e-114 382.7 0.2 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 ABK73839.1 - 5.6e-11 42.6 2.2 2.1e-05 24.4 0.2 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase CarD_CdnL_TRCF PF02559.16 ABK73840.1 - 5e-29 100.9 0.0 1.4e-28 99.4 0.0 1.9 1 0 0 1 1 1 1 CarD-like/TRCF domain TRCF PF03461.15 ABK73840.1 - 8.1e-25 87.0 0.0 1.1e-23 83.4 0.0 2.7 3 0 0 3 3 3 1 TRCF domain UvrB_inter PF17757.1 ABK73840.1 - 5.6e-21 74.5 0.0 1.4e-20 73.2 0.0 1.7 1 0 0 1 1 1 1 UvrB interaction domain Helicase_C PF00271.31 ABK73840.1 - 1.7e-17 63.7 1.1 1.3e-14 54.5 0.2 2.7 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.29 ABK73840.1 - 2e-16 60.2 1.0 6.3e-16 58.6 0.2 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 ABK73840.1 - 1.4e-05 25.1 0.0 5.5e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit LSDAT_prok PF18171.1 ABK73840.1 - 0.043 13.0 0.6 0.29 10.3 0.0 2.6 3 0 0 3 3 3 0 SLOG in TRPM, prokaryote UB2H PF14814.6 ABK73840.1 - 0.057 13.5 0.0 0.17 12.0 0.0 1.8 1 1 0 1 1 1 0 Bifunctional transglycosylase second domain DUF1474 PF07342.11 ABK73840.1 - 0.12 12.9 0.0 0.25 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1474) IstB_IS21 PF01695.17 ABK73840.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF3638 PF12340.8 ABK73840.1 - 0.18 11.1 0.0 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) GidB PF02527.15 ABK73841.1 - 2.7e-53 180.1 0.0 3.3e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G MTS PF05175.14 ABK73841.1 - 0.00019 21.1 0.0 0.00029 20.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 ABK73841.1 - 0.00091 19.9 0.0 0.0024 18.5 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABK73841.1 - 0.043 14.5 0.0 0.095 13.4 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.9 ABK73841.1 - 0.12 12.0 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_31 PF13847.6 ABK73841.1 - 0.16 11.7 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain ABC_tran PF00005.27 ABK73842.1 - 4.2e-36 124.5 0.0 5.4e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK73842.1 - 1.3e-11 44.9 0.0 5.1e-05 23.2 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK73842.1 - 1.3e-07 31.3 0.1 0.00072 19.0 0.0 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ABK73842.1 - 5e-06 27.0 0.1 8.7e-06 26.2 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 ABK73842.1 - 4.4e-05 23.1 0.0 8.8e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 ABK73842.1 - 4.9e-05 23.6 0.0 0.00026 21.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ABK73842.1 - 0.00033 20.5 0.2 0.0027 17.4 0.2 2.2 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 ABK73842.1 - 0.0012 19.0 0.5 0.031 14.5 0.5 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.9 ABK73842.1 - 0.0021 17.0 0.3 0.24 10.1 0.0 2.5 2 1 0 2 2 2 1 Predicted ATPase of the ABC class AAA_18 PF13238.6 ABK73842.1 - 0.0037 17.8 0.0 0.0066 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ABK73842.1 - 0.0038 17.2 0.0 0.0072 16.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 ABK73842.1 - 0.011 15.3 0.9 0.032 13.8 0.9 2.0 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 ABK73842.1 - 0.017 15.6 0.0 5.6 7.4 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ABK73842.1 - 0.019 14.9 0.0 0.3 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 ABK73842.1 - 0.02 15.1 0.0 0.041 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ABK73842.1 - 0.023 14.9 0.0 0.19 12.0 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 ABK73842.1 - 0.042 13.6 0.0 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 ABK73842.1 - 0.053 12.9 0.1 0.11 11.8 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.12 ABK73842.1 - 0.054 13.4 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 ABK73842.1 - 0.067 13.7 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 ABK73842.1 - 0.075 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit DUF3987 PF13148.6 ABK73842.1 - 0.097 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) ATP_bind_1 PF03029.17 ABK73842.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_15 PF13175.6 ABK73842.1 - 0.15 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.17 ABK73842.1 - 0.15 12.1 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 ABK73842.1 - 0.16 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.19 ABK73842.1 - 0.18 11.4 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain FmdA_AmdA PF03069.15 ABK73843.1 - 3.4e-109 365.1 0.0 3.8e-109 365.0 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family NucS PF01939.16 ABK73844.1 - 8.2e-94 313.2 0.0 9.1e-94 313.1 0.0 1.0 1 0 0 1 1 1 1 Endonuclease NucS UPF0102 PF02021.17 ABK73844.1 - 0.017 15.4 0.0 0.033 14.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0102 LysR_substrate PF03466.20 ABK73846.1 - 1.5e-38 132.3 4.2 2.4e-38 131.6 4.2 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 ABK73846.1 - 7.2e-22 77.1 0.6 1.9e-21 75.7 0.6 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Rib_5-P_isom_A PF06026.14 ABK73846.1 - 0.016 14.8 0.1 0.027 14.1 0.1 1.3 1 0 0 1 1 1 0 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) HTH_28 PF13518.6 ABK73846.1 - 0.083 13.0 0.0 0.34 11.1 0.0 2.2 1 0 0 1 1 1 0 Helix-turn-helix domain MarR_2 PF12802.7 ABK73846.1 - 0.086 12.7 0.2 0.086 12.7 0.2 3.1 4 0 0 4 4 4 0 MarR family YpsA PF06908.11 ABK73846.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 YspA SLOG family NTP_transf_5 PF14907.6 ABK73846.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised nucleotidyltransferase P22_Cro PF14549.6 ABK73846.1 - 0.12 12.2 0.1 0.41 10.5 0.1 1.9 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro MarR PF01047.22 ABK73846.1 - 0.16 11.9 0.2 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 MarR family Oxidored_FMN PF00724.20 ABK73847.1 - 2.7e-80 270.2 0.0 3.4e-80 269.9 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 ABK73847.1 - 5.8e-26 91.4 0.1 1e-25 90.6 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ABK73847.1 - 6e-10 39.2 0.1 2.4e-09 37.3 0.1 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ABK73847.1 - 2.2e-09 37.8 0.5 0.00013 22.5 0.2 4.4 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ABK73847.1 - 1.1e-08 34.9 1.9 1.9e-08 34.1 1.9 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ABK73847.1 - 7.7e-08 31.4 0.2 7.7e-08 31.4 0.2 1.5 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 ABK73847.1 - 7.9e-07 28.5 2.1 1.7e-06 27.4 2.1 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 ABK73847.1 - 1.1e-06 28.1 1.0 0.016 14.5 0.2 2.4 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ABK73847.1 - 1.6e-05 24.2 0.5 2.9e-05 23.4 0.5 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 ABK73847.1 - 2.8e-05 23.9 1.1 2.8e-05 23.9 1.1 3.6 2 1 2 4 4 4 1 FAD dependent oxidoreductase Dus PF01207.17 ABK73847.1 - 5.2e-05 22.5 0.1 0.0001 21.5 0.1 1.5 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Thi4 PF01946.17 ABK73847.1 - 0.00015 21.1 0.4 0.00045 19.5 0.1 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 ABK73847.1 - 0.00074 18.9 0.9 0.012 14.9 0.7 2.6 3 0 0 3 3 3 1 FAD binding domain 3HCDH_N PF02737.18 ABK73847.1 - 0.0012 18.8 0.2 0.031 14.2 0.2 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 ABK73847.1 - 0.0015 18.5 1.3 0.075 13.0 0.2 3.3 4 0 0 4 4 4 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 ABK73847.1 - 0.0016 17.8 0.2 0.0034 16.7 0.2 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase K_oxygenase PF13434.6 ABK73847.1 - 0.0021 17.2 0.0 0.11 11.7 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 ABK73847.1 - 0.0047 16.2 1.0 0.0047 16.2 1.0 1.7 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FMO-like PF00743.19 ABK73847.1 - 0.0051 15.3 0.0 0.032 12.7 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Lycopene_cycl PF05834.12 ABK73847.1 - 0.03 13.4 0.4 0.055 12.5 0.4 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.23 ABK73847.1 - 0.053 13.5 0.2 0.87 9.6 0.0 2.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus XdhC_C PF13478.6 ABK73847.1 - 0.094 13.2 0.1 0.29 11.6 0.1 1.9 1 0 0 1 1 1 0 XdhC Rossmann domain Abhydrolase_1 PF00561.20 ABK73848.1 - 3.8e-23 82.4 0.5 3.1e-13 50.0 1.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK73848.1 - 2.4e-19 70.8 3.7 2.9e-19 70.6 3.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK73848.1 - 2.2e-09 37.0 0.0 4.3e-09 36.0 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 ABK73848.1 - 0.012 15.1 0.0 0.33 10.4 0.0 2.5 2 1 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 ABK73848.1 - 0.054 13.6 0.0 0.13 12.4 0.0 1.7 2 0 0 2 2 2 0 TAP-like protein Esterase PF00756.20 ABK73848.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Ndr PF03096.14 ABK73848.1 - 0.16 10.6 0.1 0.24 10.1 0.1 1.2 1 0 0 1 1 1 0 Ndr family PRiA4_ORF3 PF07929.11 ABK73849.1 - 2.1e-51 174.1 0.0 2.5e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein Aldo_ket_red PF00248.21 ABK73850.1 - 3.9e-67 226.5 0.0 4.4e-67 226.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GntP_permease PF02447.16 ABK73851.1 - 1.1e-65 222.0 50.4 3e-34 118.5 23.3 2.0 2 0 0 2 2 2 2 GntP family permease CitMHS PF03600.16 ABK73851.1 - 2.1e-22 79.7 47.9 5.8e-22 78.2 47.9 1.7 1 1 0 1 1 1 1 Citrate transporter Na_H_antiport_2 PF13726.6 ABK73851.1 - 4.2e-05 23.6 7.7 4.2e-05 23.6 7.7 4.1 4 1 2 6 6 6 1 Na+-H+ antiporter family DUF732 PF05305.14 ABK73852.1 - 0.0027 18.1 0.9 0.0049 17.2 0.9 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF732) TetR_N PF00440.23 ABK73853.1 - 5.1e-15 55.0 1.8 1.1e-14 53.9 1.5 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_20 PF17925.1 ABK73853.1 - 2.3e-11 43.9 1.4 2.5e-11 43.8 0.3 1.6 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain HTH_Tnp_1_2 PF13022.6 ABK73853.1 - 0.21 11.7 0.0 0.38 10.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase AIRS PF00586.24 ABK73855.1 - 2.2e-17 63.5 0.3 2.2e-17 63.5 0.3 1.9 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain AIRS_C PF02769.22 ABK73855.1 - 1.3e-07 31.9 2.0 2.3e-07 31.1 2.0 1.5 1 1 0 1 1 1 1 AIR synthase related protein, C-terminal domain adh_short PF00106.25 ABK73856.1 - 1.3e-44 152.0 0.1 1.7e-44 151.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK73856.1 - 5.9e-29 101.3 0.6 8.3e-29 100.8 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK73856.1 - 1.4e-09 38.2 0.9 1.9e-09 37.7 0.9 1.1 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 ABK73856.1 - 0.034 14.7 1.0 1 10.0 0.0 3.0 2 1 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Rnk_N PF14760.6 ABK73856.1 - 0.06 13.8 2.9 1 9.9 0.6 2.6 2 0 0 2 2 2 0 Rnk N-terminus HTH_Tnp_ISL3 PF13542.6 ABK73856.1 - 0.097 12.1 1.0 0.25 10.8 0.4 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Epimerase PF01370.21 ABK73856.1 - 0.13 11.7 2.4 0.11 11.9 0.4 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Aminotran_5 PF00266.19 ABK73857.1 - 9.6e-65 218.9 4.3 1.2e-64 218.6 4.3 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aconitase PF00330.20 ABK73859.1 - 1.4e-174 581.5 0.0 2e-174 580.9 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ABK73859.1 - 3.9e-42 143.7 0.0 1e-41 142.4 0.0 1.7 2 0 0 2 2 2 1 Aconitase C-terminal domain Rieske PF00355.26 ABK73860.1 - 1.7e-18 66.3 0.0 3.2e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 ABK73860.1 - 0.033 14.1 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 Rieske-like [2Fe-2S] domain HTH_30 PF13556.6 ABK73861.1 - 1.3e-17 63.3 1.6 4.4e-17 61.6 1.6 2.0 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain GGDEF_2 PF17853.1 ABK73861.1 - 2.1e-16 60.2 4.8 2.1e-16 60.2 4.8 2.8 3 0 0 3 3 3 1 GGDEF-like domain GAF_2 PF13185.6 ABK73861.1 - 2.5e-16 60.2 0.4 2.5e-16 60.2 0.4 2.5 3 1 0 3 3 3 1 GAF domain GAF PF01590.26 ABK73861.1 - 3.3e-14 53.6 0.1 9.9e-14 52.1 0.1 1.9 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 ABK73861.1 - 3.2e-09 37.2 0.0 1.2e-08 35.4 0.0 2.0 2 0 0 2 2 2 1 GAF domain FliT PF05400.13 ABK73861.1 - 5.2 8.0 10.4 4.5 8.2 0.9 3.1 3 0 0 3 3 3 0 Flagellar protein FliT CbiA PF01656.23 ABK73862.1 - 9.5e-08 32.2 0.0 1.5e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 ABK73862.1 - 9.9e-06 25.6 0.4 0.00018 21.4 0.4 2.1 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 ABK73862.1 - 0.0001 21.6 0.4 0.00016 21.0 0.4 1.2 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_24 PF13479.6 ABK73862.1 - 0.0003 20.6 0.0 0.00039 20.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain ParA PF10609.9 ABK73862.1 - 0.0035 16.8 0.6 0.0061 16.0 0.6 1.3 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase PRK PF00485.18 ABK73862.1 - 0.017 14.9 0.1 0.025 14.3 0.1 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family CBP_BcsQ PF06564.12 ABK73862.1 - 0.037 13.5 0.4 0.32 10.4 0.4 2.1 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ NB-ARC PF00931.22 ABK73862.1 - 0.11 11.6 0.2 0.18 11.0 0.2 1.2 1 0 0 1 1 1 0 NB-ARC domain 3H PF02829.14 ABK73863.1 - 0.16 12.3 0.0 0.21 11.9 0.0 1.2 1 0 0 1 1 1 0 3H domain ECH_1 PF00378.20 ABK73865.1 - 4.9e-36 124.3 0.0 5.8e-36 124.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK73865.1 - 8.1e-18 65.0 0.0 1.8e-17 63.9 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Abhydrolase_1 PF00561.20 ABK73866.1 - 8.2e-59 199.3 0.0 1.9e-58 198.2 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 ABK73866.1 - 1.4e-17 63.7 1.0 4.5e-17 62.1 0.0 2.3 3 0 0 3 3 3 1 TAP-like protein Hydrolase_4 PF12146.8 ABK73866.1 - 0.021 14.1 0.0 0.65 9.2 0.0 2.8 3 0 0 3 3 3 0 Serine aminopeptidase, S33 GCS2 PF04107.13 ABK73867.1 - 5.3e-84 282.0 0.2 6.4e-84 281.7 0.2 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) MFS_1 PF07690.16 ABK73868.1 - 8.5e-28 97.3 52.9 5.4e-24 84.8 30.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK73868.1 - 2.6e-07 29.9 7.3 2.6e-07 29.9 7.3 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 ABK73868.1 - 5.3e-05 22.2 3.4 5.3e-05 22.2 3.4 2.1 2 0 0 2 2 2 1 MFS_1 like family MFS_3 PF05977.13 ABK73868.1 - 0.00038 19.0 9.8 0.00038 19.0 9.8 2.5 2 1 0 2 2 2 1 Transmembrane secretion effector Response_reg PF00072.24 ABK73869.1 - 6.8e-20 71.3 0.0 7.3e-20 71.2 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain DUF4007 PF13182.6 ABK73870.1 - 3.1e-89 298.9 0.0 3.8e-89 298.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4007) Transp_cyt_pur PF02133.15 ABK73871.1 - 4.1e-28 98.3 42.7 2.8e-27 95.6 42.6 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF4175 PF13779.6 ABK73871.1 - 0.27 9.1 3.1 0.43 8.4 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) adh_short_C2 PF13561.6 ABK73872.1 - 1.8e-63 214.2 1.3 2.4e-63 213.8 1.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK73872.1 - 4.3e-49 166.6 0.6 5.4e-49 166.3 0.6 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK73872.1 - 6.1e-13 49.1 1.2 8.6e-13 48.6 1.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK73872.1 - 7.8e-11 41.9 0.2 2.9e-10 40.0 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ABK73872.1 - 6.5e-06 25.8 0.2 7.8e-05 22.2 0.2 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ABK73872.1 - 0.0001 21.6 0.0 0.00014 21.2 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 ABK73872.1 - 0.022 13.9 1.2 0.094 11.8 0.4 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain NmrA PF05368.13 ABK73872.1 - 0.032 13.8 0.8 0.042 13.4 0.8 1.2 1 0 0 1 1 1 0 NmrA-like family AMP-binding PF00501.28 ABK73873.1 - 5.1e-83 279.0 0.2 6.2e-83 278.7 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK73873.1 - 1.6e-24 86.7 0.6 6.8e-24 84.6 0.2 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Aldedh PF00171.22 ABK73874.1 - 6.3e-20 71.1 8.9 6.2e-13 48.1 6.0 2.4 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Pup PF05639.11 ABK73874.1 - 0.21 12.5 0.2 0.62 11.0 0.2 1.8 1 0 0 1 1 1 0 Pup-like protein T2SSM_b PF10741.9 ABK73874.1 - 7 6.5 9.9 0.32 10.8 0.5 3.3 3 1 0 3 3 3 0 Type II secretion system (T2SS), protein M subtype b ADH_zinc_N PF00107.26 ABK73875.1 - 6.3e-10 39.1 0.1 1.2e-09 38.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ABK73875.1 - 0.016 14.5 0.4 0.029 13.7 0.4 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Fer2_2 PF01799.20 ABK73876.1 - 1.4e-29 102.0 0.3 1.4e-29 102.0 0.3 1.6 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fer2 PF00111.27 ABK73876.1 - 2e-07 30.9 2.1 2e-07 30.9 2.1 2.4 1 1 1 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 ABK73876.1 - 0.0047 16.9 5.6 0.013 15.4 5.6 2.1 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 ABK73876.1 - 0.21 11.6 4.8 12 6.0 4.8 2.9 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain DUF348 PF03990.14 ABK73876.1 - 0.83 9.4 3.0 2.9 7.7 0.0 2.6 3 0 0 3 3 3 0 G5-linked-Ubiquitin-like domain DUF433 PF04255.14 ABK73877.1 - 0.022 14.6 0.0 1.9 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF433) ADH_N PF08240.12 ABK73878.1 - 3.4e-26 91.3 0.4 5.5e-26 90.6 0.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 ABK73878.1 - 1e-14 54.1 1.2 2.1e-14 53.1 1.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.26 ABK73878.1 - 2e-12 47.2 0.3 1.3e-08 34.9 0.2 2.5 2 0 0 2 2 2 2 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ABK73878.1 - 2.4e-05 23.8 0.5 3.7e-05 23.1 0.5 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ABK73878.1 - 3.2e-05 23.4 0.0 5.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 ABK73878.1 - 0.0012 19.1 0.2 0.012 15.9 0.0 2.1 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_2 PF03446.15 ABK73878.1 - 0.0067 16.6 0.1 0.01 16.0 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.6 ABK73878.1 - 0.011 16.2 0.1 0.019 15.5 0.1 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain 3HCDH_N PF02737.18 ABK73878.1 - 0.014 15.3 0.1 0.02 14.8 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 ABK73878.1 - 0.074 13.6 0.0 0.18 12.4 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PE-PPE PF08237.11 ABK73879.1 - 2.2e-72 243.3 0.1 2.8e-72 243.0 0.1 1.1 1 0 0 1 1 1 1 PE-PPE domain Aminotran_1_2 PF00155.21 ABK73880.1 - 1.1e-59 202.5 0.0 1.2e-59 202.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 ABK73880.1 - 0.00058 18.8 0.0 0.00083 18.3 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Aminotran_5 PF00266.19 ABK73880.1 - 0.012 14.6 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Aminotran_3 PF00202.21 ABK73880.1 - 0.025 13.3 0.0 0.033 12.8 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-III Alliinase_C PF04864.13 ABK73880.1 - 0.032 13.1 0.0 0.11 11.3 0.0 1.7 2 0 0 2 2 2 0 Allinase adh_short PF00106.25 ABK73881.1 - 7e-30 103.9 0.0 9.3e-29 100.3 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK73881.1 - 6.3e-21 75.0 0.1 3.4e-20 72.6 0.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK73881.1 - 3.1e-07 30.5 0.2 4.7e-07 29.9 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK73881.1 - 0.073 12.5 0.1 0.11 11.9 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ABK73881.1 - 0.085 12.7 1.9 0.12 12.2 1.2 1.8 1 1 1 2 2 2 0 NAD(P)H-binding TIM PF00121.18 ABK73882.1 - 8.4e-87 290.6 0.0 9.6e-87 290.4 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase GAF_2 PF13185.6 ABK73884.1 - 4.6e-17 62.6 0.5 3.2e-16 59.9 0.1 2.3 2 0 0 2 2 2 1 GAF domain HisKA_3 PF07730.13 ABK73884.1 - 2.8e-15 56.6 4.4 2.8e-15 56.6 4.4 2.6 3 0 0 3 3 3 1 Histidine kinase GAF PF01590.26 ABK73884.1 - 3.1e-12 47.3 0.0 1.1e-11 45.5 0.0 2.0 1 1 0 1 1 1 1 GAF domain GAF_3 PF13492.6 ABK73884.1 - 1.2e-10 41.8 0.0 2.9e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 GAF domain HATPase_c PF02518.26 ABK73884.1 - 3.3e-09 37.2 0.0 5.8e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 ABK73884.1 - 0.0013 18.7 0.0 0.0032 17.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Lipase_GDSL_2 PF13472.6 ABK73885.1 - 2.7e-10 40.9 0.2 3.5e-10 40.6 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ABK73885.1 - 0.011 15.7 0.0 0.065 13.2 0.0 1.9 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase SLATT_fungal PF18142.1 ABK73885.1 - 0.13 12.3 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain ADH_N PF08240.12 ABK73886.1 - 2.2e-30 104.7 0.1 3.8e-30 104.0 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ABK73886.1 - 5.8e-24 84.5 0.0 8.5e-24 84.0 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ABK73886.1 - 3.4e-10 39.8 0.0 4.8e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 ABK73886.1 - 7.1e-08 33.6 0.0 1.3e-07 32.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ABK73886.1 - 0.00064 19.1 0.9 0.001 18.4 0.9 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_11 PF08241.12 ABK73886.1 - 0.001 19.7 0.3 0.0051 17.4 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABK73886.1 - 0.0013 19.4 0.2 0.0032 18.1 0.2 1.7 1 0 0 1 1 1 1 Methyltransferase domain Sacchrp_dh_NADP PF03435.18 ABK73886.1 - 0.011 15.9 0.2 0.017 15.4 0.2 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GFO_IDH_MocA PF01408.22 ABK73886.1 - 0.014 16.2 0.2 0.19 12.6 0.2 2.1 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold CMAS PF02353.20 ABK73886.1 - 0.029 13.7 0.0 0.042 13.1 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase ADH_N_2 PF16884.5 ABK73886.1 - 0.053 13.4 0.0 0.097 12.6 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase TrkA_N PF02254.18 ABK73886.1 - 0.078 13.2 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 ABK73886.1 - 0.2 11.2 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain peroxidase PF00141.23 ABK73887.1 - 1.8e-83 279.7 0.0 1.2e-43 149.4 0.0 2.2 2 0 0 2 2 2 2 Peroxidase GST_C_3 PF14497.6 ABK73887.1 - 0.043 14.0 0.0 6.1 7.1 0.0 2.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain ABC_tran PF00005.27 ABK73888.1 - 2e-32 112.6 0.0 3e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 ABK73888.1 - 7.2e-16 58.1 1.3 2.1e-15 56.6 1.3 1.9 1 0 0 1 1 1 1 TOBE domain TOBE PF03459.17 ABK73888.1 - 3.8e-05 23.9 0.9 0.00014 22.1 0.9 2.0 1 0 0 1 1 1 1 TOBE domain AAA_21 PF13304.6 ABK73888.1 - 0.0006 19.7 0.0 0.15 11.8 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ABK73888.1 - 0.013 15.9 0.7 0.037 14.4 0.4 1.9 1 1 1 2 2 2 0 AAA ATPase domain SMC_N PF02463.19 ABK73888.1 - 0.03 13.7 0.1 0.24 10.8 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain TniB PF05621.11 ABK73888.1 - 0.031 13.7 0.3 0.21 11.0 0.2 2.0 2 0 0 2 2 2 0 Bacterial TniB protein AAA_22 PF13401.6 ABK73888.1 - 0.037 14.3 0.4 0.16 12.3 0.4 2.0 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ABK73888.1 - 0.14 12.4 0.6 0.54 10.5 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 ABK73888.1 - 0.16 12.4 0.0 0.49 10.8 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MFS_1 PF07690.16 ABK73889.1 - 1.1e-43 149.6 58.9 9.1e-35 120.2 35.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK73889.1 - 3.6e-37 128.3 24.7 2.6e-30 105.7 3.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter DuoxA PF10204.9 ABK73889.1 - 0.0063 15.6 0.6 0.017 14.2 0.6 1.7 1 0 0 1 1 1 1 Dual oxidase maturation factor DUF3810 PF12725.7 ABK73889.1 - 3.9 6.7 4.6 0.57 9.5 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) NMT1 PF09084.11 ABK73890.1 - 1.8e-17 64.0 0.4 2.3e-17 63.6 0.4 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 ABK73890.1 - 6.9e-10 39.0 2.1 3.1e-09 36.9 2.1 1.8 1 1 0 1 1 1 1 NMT1-like family VitK2_biosynth PF02621.14 ABK73890.1 - 0.023 14.2 0.2 0.7 9.4 0.0 2.2 2 0 0 2 2 2 0 Menaquinone biosynthesis Acyl-CoA_dh_1 PF00441.24 ABK73891.1 - 2.5e-16 60.2 2.1 5.2e-16 59.2 2.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK73891.1 - 5.6e-13 49.5 0.9 1.6e-12 48.0 0.0 2.2 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain ADH_N PF08240.12 ABK73892.1 - 1.7e-30 105.1 1.5 2.9e-30 104.4 1.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ABK73892.1 - 7.9e-17 61.5 1.8 1.2e-16 60.9 1.8 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ABK73892.1 - 1.2e-05 26.4 0.1 2.3e-05 25.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AP_endonuc_2 PF01261.24 ABK73892.1 - 0.088 12.2 0.2 0.21 11.0 0.2 1.6 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel PMT_2 PF13231.6 ABK73894.1 - 1.7e-13 51.1 9.8 1.7e-13 51.1 9.8 2.5 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Glyoxalase PF00903.25 ABK73895.1 - 2.8e-23 82.5 0.0 1.9e-19 70.1 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ABK73895.1 - 1.8e-06 28.7 0.0 0.00014 22.6 0.0 2.4 2 0 0 2 2 2 1 Glyoxalase-like domain EccE PF11203.8 ABK73896.1 - 1.6e-10 41.2 3.2 1.6e-10 41.2 3.2 2.9 3 1 0 3 3 3 1 Putative type VII ESX secretion system translocon, EccE mono-CXXC PF15626.6 ABK73896.1 - 0.57 10.6 3.2 0.36 11.2 0.9 1.8 2 0 0 2 2 2 0 single CXXC unit Trigger_N PF05697.13 ABK73897.1 - 2.4e-42 144.6 0.6 2.4e-42 144.6 0.6 2.8 2 1 1 3 3 3 1 Bacterial trigger factor protein (TF) Trigger_C PF05698.14 ABK73897.1 - 1.8e-38 132.1 16.8 9.4e-37 126.5 13.7 3.0 3 0 0 3 3 3 2 Bacterial trigger factor protein (TF) C-terminus FKBP_C PF00254.28 ABK73897.1 - 1.9e-06 28.1 0.1 5.5e-06 26.6 0.1 1.8 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase SurA_N_3 PF13624.6 ABK73897.1 - 0.0015 18.3 9.9 1.1 9.0 0.7 4.1 3 1 1 4 4 4 2 SurA N-terminal domain DUF5064 PF16703.5 ABK73897.1 - 0.048 14.1 0.1 0.53 10.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5064) AIF-MLS PF14962.6 ABK73897.1 - 0.084 12.8 0.3 0.084 12.8 0.3 3.1 3 0 0 3 3 3 0 Mitochondria Localisation Sequence HALZ PF02183.18 ABK73897.1 - 0.11 12.7 0.6 1.2 9.5 0.3 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper Usp PF00582.26 ABK73898.1 - 4.9e-27 95.2 9.0 6.5e-12 46.2 0.4 3.5 2 2 1 3 3 3 3 Universal stress protein family adh_short_C2 PF13561.6 ABK73899.1 - 9.2e-60 202.1 0.1 1.2e-59 201.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK73899.1 - 4.7e-43 146.9 0.0 5.8e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK73899.1 - 1.5e-11 44.6 0.2 2e-11 44.1 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK73899.1 - 2.7e-05 23.7 0.1 0.00013 21.5 0.2 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ABK73899.1 - 2.8e-05 24.1 1.2 5.4e-05 23.2 1.2 1.5 1 0 0 1 1 1 1 NAD(P)H-binding ADH_zinc_N PF00107.26 ABK73899.1 - 0.00017 21.6 1.5 0.00033 20.6 0.7 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 ABK73899.1 - 0.0025 18.1 0.1 0.0036 17.6 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 ABK73899.1 - 0.017 15.2 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 ABK73899.1 - 0.025 15.2 0.1 0.055 14.1 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 ABK73899.1 - 0.03 14.6 0.1 0.055 13.7 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain NmrA PF05368.13 ABK73899.1 - 0.16 11.5 0.4 0.25 10.8 0.4 1.3 1 0 0 1 1 1 0 NmrA-like family Na_H_Exchanger PF00999.21 ABK73900.1 - 1.2e-52 179.0 46.9 1.5e-52 178.7 46.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Urease_beta PF00699.20 ABK73901.1 - 2.1e-35 120.7 0.0 3.3e-35 120.0 0.0 1.3 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.18 ABK73901.1 - 2e-30 105.0 0.1 2.9e-30 104.5 0.1 1.2 1 0 0 1 1 1 1 Urease, gamma subunit T7SS_ESX_EspC PF10824.8 ABK73903.1 - 6.3e-28 97.2 2.4 7.7e-28 96.9 2.4 1.0 1 0 0 1 1 1 1 Excreted virulence factor EspC, type VII ESX diderm IF2_N PF04760.15 ABK73903.1 - 0.0088 15.8 0.1 0.65 9.9 0.0 2.3 2 0 0 2 2 2 2 Translation initiation factor IF-2, N-terminal region Sigma70_r3 PF04539.16 ABK73903.1 - 0.042 13.9 0.1 12 6.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-70 region 3 Fer4_16 PF13484.6 ABK73904.1 - 6.5e-06 27.0 2.8 5.9e-05 23.9 2.9 2.2 1 1 1 2 2 2 1 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 ABK73904.1 - 2e-05 24.6 0.4 0.002 18.2 0.2 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4 PF00037.27 ABK73904.1 - 5.9e-05 22.7 3.4 5.9e-05 22.7 3.4 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_9 PF13187.6 ABK73904.1 - 0.00013 22.0 0.2 0.0052 16.9 0.0 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 ABK73904.1 - 0.00021 21.2 10.0 0.00052 20.0 3.6 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_8 PF13183.6 ABK73904.1 - 0.00097 19.5 0.3 0.046 14.2 0.2 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 ABK73904.1 - 0.0015 19.1 7.5 0.0078 16.8 2.5 2.5 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 ABK73904.1 - 0.0018 18.4 1.1 0.073 13.3 0.9 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 ABK73904.1 - 0.0024 18.4 0.9 0.22 12.1 0.4 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 ABK73904.1 - 0.0051 16.9 5.9 0.0069 16.5 1.7 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_3 PF12798.7 ABK73904.1 - 0.011 16.6 11.5 0.04 14.9 6.2 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 ABK73904.1 - 0.015 15.8 2.8 0.015 15.8 2.8 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain EccE PF11203.8 ABK73904.1 - 0.14 12.5 2.0 0.32 11.4 0.1 2.3 3 0 0 3 3 3 0 Putative type VII ESX secretion system translocon, EccE Fer4_2 PF12797.7 ABK73904.1 - 0.58 10.4 11.6 0.081 13.1 3.3 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain adh_short_C2 PF13561.6 ABK73905.1 - 1.2e-52 178.9 8.6 3.9e-51 173.9 5.7 2.7 2 1 1 3 3 3 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK73905.1 - 2.2e-45 154.5 7.5 4.3e-45 153.6 5.5 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 ABK73905.1 - 5.6e-14 52.4 3.1 1.4e-13 51.1 3.1 1.7 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK73905.1 - 0.0005 19.6 1.0 0.00082 18.9 1.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HU-CCDC81_euk_2 PF18289.1 ABK73905.1 - 0.018 15.2 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 Aldo_ket_red PF00248.21 ABK73906.1 - 7.6e-56 189.5 0.0 6.2e-54 183.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Semialdhyde_dh PF01118.24 ABK73906.1 - 0.084 13.3 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DEAD PF00270.29 ABK73907.1 - 4.1e-17 62.5 0.0 1.2e-16 61.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ABK73907.1 - 1.8e-14 54.0 0.0 8.8e-14 51.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ABK73907.1 - 5.2e-08 33.1 0.0 7.4e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RecQ_Zn_bind PF16124.5 ABK73907.1 - 8.5e-05 23.2 0.6 0.00019 22.1 0.6 1.6 1 0 0 1 1 1 1 RecQ zinc-binding Pribosyltran PF00156.27 ABK73907.1 - 0.00084 18.9 0.0 0.0037 16.8 0.0 2.0 2 0 0 2 2 2 1 Phosphoribosyl transferase domain HTH_20 PF12840.7 ABK73907.1 - 0.0013 18.8 0.2 0.022 14.8 0.1 2.9 2 0 0 2 2 2 1 Helix-turn-helix domain FCD PF07729.12 ABK73908.1 - 4.3e-23 82.1 10.7 8e-23 81.2 10.7 1.4 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 ABK73908.1 - 4.5e-15 55.1 0.1 8.9e-15 54.1 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family MaoC_dehydrat_N PF13452.6 ABK73909.1 - 6.3e-33 113.7 0.2 3.2e-26 92.0 0.2 2.2 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase MaoC_dehydratas PF01575.19 ABK73909.1 - 2.8e-23 81.8 0.0 6e-17 61.4 0.0 2.6 3 0 0 3 3 3 2 MaoC like domain PGM1_C PF18105.1 ABK73909.1 - 0.085 12.4 0.1 0.22 11.0 0.1 1.7 1 0 0 1 1 1 0 PGM1 C-terminal domain ABC_tran PF00005.27 ABK73910.1 - 2.4e-26 92.9 0.0 6.1e-26 91.6 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 ABK73910.1 - 8.7e-06 25.8 0.2 7.3e-05 22.7 0.0 2.0 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ABK73910.1 - 0.00016 21.6 0.0 0.00027 20.9 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 ABK73910.1 - 0.00024 21.6 0.2 0.00034 21.0 0.2 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 ABK73910.1 - 0.0009 18.9 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 ABK73910.1 - 0.0038 17.5 0.0 0.011 16.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 ABK73910.1 - 0.01 16.1 0.0 0.18 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 ABK73910.1 - 0.011 15.9 0.1 0.16 12.2 0.4 2.6 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 ABK73910.1 - 0.054 13.6 0.0 0.097 12.8 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 ABK73910.1 - 0.062 13.5 0.1 0.15 12.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.19 ABK73910.1 - 0.07 12.6 0.0 6.3 6.2 0.0 2.2 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain NACHT PF05729.12 ABK73910.1 - 0.094 12.6 0.2 0.14 12.0 0.2 1.6 1 1 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 ABK73910.1 - 0.14 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 ABK73910.1 - 0.18 10.9 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 ABK73911.1 - 1.6e-20 74.2 1.8 1.6e-20 74.2 1.8 3.1 3 1 0 3 3 3 1 AAA ATPase domain GerE PF00196.19 ABK73911.1 - 2.9e-15 55.5 0.0 5.1e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family AAA_22 PF13401.6 ABK73911.1 - 2.2e-05 24.7 0.0 7.9e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain HTH_23 PF13384.6 ABK73911.1 - 0.00096 18.9 0.2 0.0054 16.5 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_24 PF13412.6 ABK73911.1 - 0.0028 17.2 0.0 0.011 15.3 0.0 2.1 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding NACHT PF05729.12 ABK73911.1 - 0.0066 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain HTH_10 PF04967.12 ABK73911.1 - 0.029 14.2 0.0 0.13 12.1 0.0 2.2 1 0 0 1 1 1 0 HTH DNA binding domain PGA_cap PF09587.10 ABK73911.1 - 0.042 13.3 0.7 0.077 12.4 0.7 1.3 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap RsdA_SigD_bd PF16751.5 ABK73911.1 - 0.049 13.9 2.5 4 7.8 0.1 3.2 2 0 0 2 2 2 0 Anti-sigma-D factor RsdA to sigma factor binding region Sigma70_r4_2 PF08281.12 ABK73911.1 - 0.053 13.2 0.0 0.3 10.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 AFG1_ATPase PF03969.16 ABK73911.1 - 0.17 10.8 1.2 1.4 7.7 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase MTES_1575 PF18741.1 ABK73912.1 - 0.003 17.7 0.0 0.0059 16.8 0.0 1.4 1 0 0 1 1 1 1 REase_MTES_1575 DUF559 PF04480.12 ABK73912.1 - 0.017 15.0 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF559) AMP-binding PF00501.28 ABK73913.1 - 1.6e-87 293.8 0.7 2.2e-87 293.4 0.7 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK73913.1 - 1.1e-12 48.8 0.7 1.1e-12 48.8 0.7 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 ABK73913.1 - 0.05 12.4 0.0 0.7 8.7 0.0 2.0 2 0 0 2 2 2 0 GH3 auxin-responsive promoter Na_H_antiporter PF03553.14 ABK73915.1 - 5.5e-11 42.2 18.8 5.5e-11 42.2 18.8 2.4 2 1 0 2 2 2 1 Na+/H+ antiporter family DcuC PF03606.15 ABK73915.1 - 0.011 14.3 26.2 0.011 14.2 25.3 1.5 1 1 0 1 1 1 0 C4-dicarboxylate anaerobic carrier CitMHS PF03600.16 ABK73915.1 - 8.6 5.5 54.0 2.6e+02 0.6 54.0 2.5 1 1 0 1 1 1 0 Citrate transporter Putative_PNPOx PF01243.20 ABK73917.1 - 1.2e-22 79.9 0.0 1.8e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 ABK73917.1 - 2.6e-10 40.4 0.3 3.2e-10 40.2 0.3 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 ABK73917.1 - 2e-08 33.9 0.0 3e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Aldedh PF00171.22 ABK73918.1 - 6.5e-149 496.4 0.0 7.8e-149 496.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family bPH_2 PF03703.14 ABK73919.1 - 7.5e-25 86.9 2.2 1.4e-13 50.9 0.2 3.6 3 1 0 3 3 3 3 Bacterial PH domain FA_desaturase PF00487.24 ABK73919.1 - 6.9 6.4 13.1 1.2 8.9 2.5 3.0 3 0 0 3 3 3 0 Fatty acid desaturase ABC_tran PF00005.27 ABK73920.1 - 2.1e-31 109.3 0.0 2.7e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK73920.1 - 4.4e-09 36.6 1.1 0.00043 20.2 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK73920.1 - 5.1e-06 26.1 0.0 0.021 14.2 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 ABK73920.1 - 4.1e-05 23.5 0.0 7.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 ABK73920.1 - 0.00057 19.6 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 ABK73920.1 - 0.0047 17.3 0.0 0.0058 17.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 ABK73920.1 - 0.0067 16.0 0.2 0.17 11.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 ABK73920.1 - 0.011 15.7 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_22 PF13401.6 ABK73920.1 - 0.015 15.5 0.4 0.07 13.4 0.4 2.1 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ABK73920.1 - 0.023 14.8 0.1 0.037 14.1 0.1 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_15 PF13175.6 ABK73920.1 - 0.026 14.2 0.0 0.4 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 ABK73920.1 - 0.047 13.4 0.1 0.11 12.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ABK73920.1 - 0.066 13.4 1.4 0.32 11.1 1.4 2.0 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ABK73920.1 - 0.07 13.6 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ABK73920.1 - 0.11 13.0 0.1 0.21 12.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ABK73920.1 - 0.16 11.7 0.1 0.37 10.5 0.1 1.6 2 0 0 2 2 2 0 AAA domain Amidohydro_2 PF04909.14 ABK73921.1 - 2.3e-46 158.9 0.6 2.9e-46 158.6 0.6 1.1 1 0 0 1 1 1 1 Amidohydrolase FAD_binding_3 PF01494.19 ABK73922.1 - 1.5e-09 37.6 0.1 1.5e-09 37.6 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Proton_antipo_M PF00361.20 ABK73923.1 - 2e-54 184.8 20.4 2e-54 184.8 20.4 2.3 2 0 0 2 2 2 1 Proton-conducting membrane transporter MnhB PF04039.13 ABK73923.1 - 9.5e-30 103.5 14.8 9.5e-30 103.5 14.8 7.5 5 2 7 12 12 12 1 Domain related to MnhB subunit of Na+/H+ antiporter DUF4040 PF13244.6 ABK73923.1 - 3.5e-19 68.7 11.3 3.5e-19 68.7 11.3 6.6 7 1 0 7 7 7 1 Domain of unknown function (DUF4040) Proton_antipo_N PF00662.20 ABK73923.1 - 1.2e-06 28.5 0.2 1.2e-06 28.5 0.2 2.7 3 0 0 3 3 3 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus GAF_2 PF13185.6 ABK73924.1 - 5.2e-21 75.4 8.2 4.4e-11 43.2 0.7 2.7 3 0 0 3 3 3 2 GAF domain GAF PF01590.26 ABK73924.1 - 1.1e-13 51.9 2.8 5.6e-06 27.0 0.1 2.8 3 0 0 3 3 3 2 GAF domain HisKA_3 PF07730.13 ABK73924.1 - 1.1e-10 41.8 2.4 1.1e-10 41.8 2.4 2.5 2 0 0 2 2 2 1 Histidine kinase GAF_3 PF13492.6 ABK73924.1 - 1.7e-10 41.3 5.1 1.8e-06 28.3 0.2 3.2 3 1 0 3 3 3 2 GAF domain HATPase_c PF02518.26 ABK73924.1 - 5.8e-09 36.5 0.5 1.7e-07 31.7 0.5 2.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 ABK73924.1 - 0.00011 22.1 0.1 0.00033 20.6 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 ABK73924.1 - 0.00033 20.5 0.1 0.0006 19.7 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TraH_2 PF06871.11 ABK73924.1 - 0.0096 15.6 0.6 0.02 14.6 0.6 1.4 1 0 0 1 1 1 1 TraH_2 SLATT_fungal PF18142.1 ABK73924.1 - 0.015 15.3 0.0 0.04 13.9 0.0 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain SnoaL_2 PF12680.7 ABK73925.1 - 1.6e-12 48.0 0.1 2e-12 47.7 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain NTF2 PF02136.20 ABK73925.1 - 1.3e-07 32.2 0.0 1.4e-07 32.1 0.0 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 ABK73925.1 - 4.3e-05 23.9 0.1 5.3e-05 23.6 0.1 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_4 PF13577.6 ABK73925.1 - 0.00058 20.0 0.1 0.00066 19.8 0.1 1.3 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 ABK73925.1 - 0.0019 18.4 0.0 0.0025 18.1 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 ABK73925.1 - 0.019 14.8 0.0 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase CaMKII_AD PF08332.10 ABK73925.1 - 0.067 13.3 0.0 0.078 13.1 0.0 1.1 1 0 0 1 1 1 0 Calcium/calmodulin dependent protein kinase II association domain HTH_30 PF13556.6 ABK73926.1 - 3.6e-23 81.1 1.2 1.2e-22 79.5 0.2 2.4 3 0 0 3 3 3 1 PucR C-terminal helix-turn-helix domain GGDEF_2 PF17853.1 ABK73926.1 - 1e-05 25.8 1.8 1e-05 25.8 1.8 3.0 3 0 0 3 3 3 1 GGDEF-like domain HTH_1 PF00126.27 ABK73926.1 - 0.00021 21.1 0.0 0.0015 18.4 0.0 2.4 3 0 0 3 3 3 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_23 PF13384.6 ABK73926.1 - 0.11 12.3 0.9 6.6 6.7 0.0 3.6 4 0 0 4 4 4 0 Homeodomain-like domain Peripla_BP_4 PF13407.6 ABK73926.1 - 0.16 11.5 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 Periplasmic binding protein domain Ribosomal_L12_N PF16320.5 ABK73926.1 - 0.32 10.7 2.9 1.7 8.4 2.9 2.3 1 0 0 1 1 1 0 Ribosomal protein L7/L12 dimerisation domain FAD_binding_2 PF00890.24 ABK73927.1 - 6e-74 249.6 5.7 6.8e-74 249.4 5.7 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ABK73927.1 - 7.5e-13 48.8 2.3 1.2e-12 48.1 2.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ABK73927.1 - 4.9e-07 29.5 4.2 2.8e-06 27.0 5.3 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ABK73927.1 - 0.00011 21.0 6.0 0.00019 20.3 5.3 1.6 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 ABK73927.1 - 0.00018 20.9 2.0 0.00018 20.9 2.0 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 ABK73927.1 - 0.00018 20.9 0.6 0.00018 20.9 0.6 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ABK73927.1 - 0.00083 19.5 4.0 0.0028 17.9 4.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 ABK73927.1 - 0.26 10.6 4.8 0.45 9.8 4.8 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Usp PF00582.26 ABK73928.1 - 1e-53 181.6 7.4 3.6e-28 98.8 0.2 2.0 2 0 0 2 2 2 2 Universal stress protein family Citrate_synt PF00285.21 ABK73929.1 - 5e-118 394.3 0.0 5.7e-118 394.1 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Sulfatase PF00884.23 ABK73930.1 - 7.2e-54 183.3 0.0 1e-53 182.8 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 ABK73930.1 - 0.016 15.9 0.3 0.18 12.6 0.3 2.2 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase DuffyBP_N PF12377.8 ABK73930.1 - 0.28 11.6 0.9 2 8.9 0.1 2.2 2 0 0 2 2 2 0 Duffy binding protein N terminal Enolase_C PF00113.22 ABK73932.1 - 3.3e-126 420.5 0.0 4.2e-126 420.2 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 ABK73932.1 - 5.2e-57 191.6 0.0 9.1e-57 190.9 0.0 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 ABK73932.1 - 9.6e-11 41.7 0.0 1.8e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 ABK73932.1 - 0.0024 17.1 0.0 0.0041 16.3 0.0 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus OpuAC PF04069.12 ABK73933.1 - 3.2e-57 194.0 0.0 3.7e-57 193.8 0.0 1.0 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system Invasin_D3 PF09134.10 ABK73933.1 - 0.0055 17.0 0.1 0.015 15.6 0.1 1.7 1 0 0 1 1 1 1 Invasin, domain 3 LPAM_2 PF13627.6 ABK73933.1 - 0.22 11.4 5.7 0.38 10.7 5.7 1.4 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site GerE PF00196.19 ABK73934.1 - 1.7e-14 53.1 0.0 3e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family GAF_2 PF13185.6 ABK73934.1 - 5.4e-05 23.5 1.9 8.2e-05 22.9 0.2 2.1 2 1 0 2 2 2 1 GAF domain GAF PF01590.26 ABK73934.1 - 8.4e-05 23.2 0.0 0.00016 22.3 0.0 1.5 1 0 0 1 1 1 1 GAF domain Sigma70_r4_2 PF08281.12 ABK73934.1 - 0.0014 18.2 0.1 0.0043 16.7 0.1 1.9 1 0 0 1 1 1 1 Sigma-70, region 4 GAF_3 PF13492.6 ABK73934.1 - 0.04 14.3 0.7 0.087 13.2 0.2 1.8 2 0 0 2 2 2 0 GAF domain Lyase_aromatic PF00221.19 ABK73935.1 - 8.3e-181 601.7 12.1 1.1e-180 601.3 12.1 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase BetR PF08667.10 ABK73935.1 - 0.031 14.3 0.1 0.19 11.8 0.0 2.3 3 0 0 3 3 3 0 BetR domain HxlR PF01638.17 ABK73936.1 - 4.8e-31 106.5 0.0 1.3e-18 66.6 0.3 2.2 2 0 0 2 2 2 2 HxlR-like helix-turn-helix PadR PF03551.14 ABK73936.1 - 0.00043 20.2 0.0 0.18 11.8 0.0 2.3 2 0 0 2 2 2 2 Transcriptional regulator PadR-like family MarR_2 PF12802.7 ABK73936.1 - 0.0063 16.4 0.0 1.5 8.8 0.0 2.5 2 0 0 2 2 2 2 MarR family zinc-ribbons_6 PF07191.12 ABK73936.1 - 0.064 13.3 0.8 2.5 8.1 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbons LIM PF00412.22 ABK73936.1 - 0.075 13.3 1.3 2.3 8.5 0.1 2.3 2 0 0 2 2 2 0 LIM domain HTH_20 PF12840.7 ABK73936.1 - 0.099 12.7 0.0 4.4 7.4 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain DUF35_N PF12172.8 ABK73936.1 - 0.4 10.6 6.0 3.1 7.8 0.1 2.6 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) GerE PF00196.19 ABK73937.1 - 1.2e-13 50.4 0.0 2.3e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family AAA_16 PF13191.6 ABK73937.1 - 6.6e-09 36.4 0.0 6.6e-09 36.4 0.0 3.8 2 2 1 3 3 2 1 AAA ATPase domain TPR_19 PF14559.6 ABK73937.1 - 8.1e-07 29.5 11.4 3.5e-05 24.2 0.8 4.3 4 0 0 4 4 3 2 Tetratricopeptide repeat AAA_22 PF13401.6 ABK73937.1 - 8.2e-06 26.1 0.0 8.6e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain Sigma70_r4_2 PF08281.12 ABK73937.1 - 5.4e-05 22.8 0.3 0.00018 21.1 0.3 1.9 1 0 0 1 1 1 1 Sigma-70, region 4 AAA_5 PF07728.14 ABK73937.1 - 0.00019 21.5 0.0 0.00039 20.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 ABK73937.1 - 0.0022 17.9 0.0 0.0091 15.9 0.0 1.9 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 ABK73937.1 - 0.0024 17.1 0.0 0.0055 15.9 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_30 PF13604.6 ABK73937.1 - 0.003 17.3 1.2 0.003 17.3 1.2 3.0 2 1 1 3 3 3 1 AAA domain Sigma70_ECF PF07638.11 ABK73937.1 - 0.0035 17.3 0.0 0.0091 15.9 0.0 1.6 1 0 0 1 1 1 1 ECF sigma factor AAA_28 PF13521.6 ABK73937.1 - 0.0036 17.5 0.0 0.022 15.0 0.1 2.4 2 0 0 2 2 1 1 AAA domain AAA PF00004.29 ABK73937.1 - 0.0038 17.7 0.0 0.008 16.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) HTH_23 PF13384.6 ABK73937.1 - 0.007 16.1 0.2 0.007 16.1 0.2 3.1 3 0 0 3 3 3 1 Homeodomain-like domain NACHT PF05729.12 ABK73937.1 - 0.0089 16.0 0.6 0.035 14.0 0.3 2.1 2 0 0 2 2 2 1 NACHT domain RuvB_N PF05496.12 ABK73937.1 - 0.01 15.6 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RsgA_GTPase PF03193.16 ABK73937.1 - 0.016 15.1 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 ABK73937.1 - 0.027 14.6 0.2 0.087 13.0 0.2 1.9 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 ABK73937.1 - 0.042 13.8 0.0 0.079 13.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TPR_4 PF07721.14 ABK73937.1 - 0.051 14.2 0.9 0.051 14.2 0.9 7.4 8 0 0 8 8 5 0 Tetratricopeptide repeat AAA_18 PF13238.6 ABK73937.1 - 0.076 13.6 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain TPR_7 PF13176.6 ABK73937.1 - 0.081 13.0 0.6 7.6 6.8 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat HTH_40 PF14493.6 ABK73937.1 - 0.087 13.3 0.0 0.32 11.5 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain RNA_helicase PF00910.22 ABK73937.1 - 0.14 12.6 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 ABK73937.1 - 0.25 10.9 0.1 0.43 10.1 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TPR_2 PF07719.17 ABK73937.1 - 0.42 10.8 9.4 0.32 11.2 0.3 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat Isochorismatase PF00857.20 ABK73938.1 - 5.2e-37 127.7 0.0 7e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family AP_endonuc_2 PF01261.24 ABK73938.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.3 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel tRNA-synt_1b PF00579.25 ABK73939.1 - 6.5e-84 281.7 0.0 7.8e-84 281.4 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Eno-Rase_NADH_b PF12242.8 ABK73939.1 - 0.032 14.0 0.0 0.075 12.8 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HMGL-like PF00682.19 ABK73940.1 - 3e-39 135.2 0.4 3.5e-39 134.9 0.4 1.0 1 0 0 1 1 1 1 HMGL-like His_Phos_1 PF00300.22 ABK73941.1 - 6.7e-29 101.0 0.3 7.6e-29 100.8 0.3 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) FCD PF07729.12 ABK73942.1 - 4.8e-25 88.4 5.7 1.3e-24 87.0 5.7 1.7 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 ABK73942.1 - 1.1e-19 69.9 2.2 1.7e-19 69.2 0.6 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family Rrf2 PF02082.20 ABK73942.1 - 0.00018 21.8 0.3 0.00072 19.9 0.0 2.1 2 0 0 2 2 2 1 Transcriptional regulator HTH_27 PF13463.6 ABK73942.1 - 0.00042 20.7 0.3 0.8 10.2 0.0 3.0 3 1 1 4 4 3 2 Winged helix DNA-binding domain HTH_11 PF08279.12 ABK73942.1 - 0.0013 18.6 0.0 0.02 14.8 0.0 2.4 2 0 0 2 2 2 1 HTH domain TrmB PF01978.19 ABK73942.1 - 0.0014 18.5 0.1 0.009 15.9 0.0 2.3 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HrcA_DNA-bdg PF03444.15 ABK73942.1 - 0.0024 17.5 0.0 0.091 12.4 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding MarR_2 PF12802.7 ABK73942.1 - 0.005 16.7 0.4 0.024 14.5 0.0 2.3 2 0 0 2 2 2 1 MarR family HTH_DeoR PF08220.12 ABK73942.1 - 0.0067 16.2 0.0 0.023 14.4 0.0 1.9 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_Crp_2 PF13545.6 ABK73942.1 - 0.015 15.3 0.0 0.037 14.0 0.0 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_IclR PF09339.10 ABK73942.1 - 0.021 14.6 0.6 0.082 12.7 0.1 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_24 PF13412.6 ABK73942.1 - 0.023 14.2 0.0 0.052 13.1 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding CENP-B_N PF04218.13 ABK73942.1 - 0.03 14.0 0.0 0.1 12.3 0.0 1.9 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain FliG_C PF01706.16 ABK73942.1 - 0.032 14.4 0.2 0.2 11.8 0.1 2.2 2 1 0 2 2 2 0 FliG C-terminal domain HTH_28 PF13518.6 ABK73942.1 - 0.071 13.3 0.3 0.55 10.4 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_10 PF04967.12 ABK73942.1 - 0.071 12.9 0.2 0.25 11.2 0.0 2.0 2 0 0 2 2 2 0 HTH DNA binding domain MarR PF01047.22 ABK73942.1 - 0.12 12.3 0.1 0.47 10.4 0.0 2.0 2 0 0 2 2 1 0 MarR family PHBC_N PF12551.8 ABK73942.1 - 0.12 12.1 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase N terminal DUF2939 PF11159.8 ABK73942.1 - 0.58 10.6 4.8 17 5.9 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2939) RuvA_C PF07499.13 ABK73942.1 - 1.6 9.3 4.4 8.1 7.0 0.1 3.5 3 0 0 3 3 3 0 RuvA, C-terminal domain DUF732 PF05305.14 ABK73943.1 - 6.4e-08 32.9 0.1 1.1e-06 28.9 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF732) zinc_ribbon_2 PF13240.6 ABK73943.1 - 2.4 8.0 7.7 3.4 7.5 0.4 3.2 3 0 0 3 3 3 0 zinc-ribbon domain peroxidase PF00141.23 ABK73944.1 - 5.4e-82 274.9 0.0 7.3e-46 156.7 0.0 2.7 3 0 0 3 3 3 2 Peroxidase RHH_1 PF01402.21 ABK73944.1 - 0.059 13.3 0.2 0.14 12.1 0.2 1.7 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family Tad PF13400.6 ABK73945.1 - 3.5e-06 27.2 22.8 3.5e-06 27.2 22.8 2.0 2 1 0 2 2 2 1 Putative Flp pilus-assembly TadE/G-like DUF2771 PF10969.8 ABK73945.1 - 0.059 13.4 0.7 0.068 13.2 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2771) YbgS PF13985.6 ABK73945.1 - 9.7 6.5 6.5 16 5.8 6.0 1.8 1 1 0 1 1 1 0 YbgS-like protein Peptidase_M15 PF01427.17 ABK73946.1 - 4.1e-51 173.6 0.4 1.4e-49 168.6 0.4 2.1 1 1 0 1 1 1 1 D-ala-D-ala dipeptidase Mce4_CUP1 PF11887.8 ABK73948.1 - 5.8e-95 317.6 0.0 7.6e-95 317.2 0.0 1.1 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative MlaD PF02470.20 ABK73948.1 - 2.1e-14 53.6 0.1 5e-14 52.3 0.1 1.7 2 0 0 2 2 2 1 MlaD protein ATP-synt_I PF03899.15 ABK73949.1 - 6e-07 29.8 12.1 8.1e-07 29.4 12.1 1.2 1 0 0 1 1 1 1 ATP synthase I chain DUF2678 PF10856.8 ABK73949.1 - 0.32 10.9 3.1 2.5 8.0 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) TMEM100 PF16311.5 ABK73949.1 - 0.42 10.2 3.7 0.12 11.9 0.5 1.7 2 0 0 2 2 2 0 Transmembrane protein 100 DUF2178 PF09946.9 ABK73949.1 - 0.52 10.5 6.9 0.91 9.7 6.9 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2178) Abhydrolase_9_N PF15420.6 ABK73949.1 - 0.54 10.2 6.4 0.097 12.7 1.8 2.0 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus PRA1 PF03208.19 ABK73949.1 - 0.83 9.3 9.9 5.8 6.5 10.3 1.9 1 1 0 1 1 1 0 PRA1 family protein DUF2070 PF09843.9 ABK73949.1 - 0.91 7.7 10.2 1.1 7.5 10.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) COX4_pro PF03626.14 ABK73949.1 - 3.6 8.1 16.3 0.89 10.0 6.1 2.2 2 0 0 2 2 2 0 Prokaryotic Cytochrome C oxidase subunit IV BPD_transp_1 PF00528.22 ABK73950.1 - 6.9e-20 71.5 15.2 6.9e-20 71.5 15.2 1.5 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component ABC2_membrane_2 PF12679.7 ABK73950.1 - 1.5 8.0 11.3 0.072 12.4 5.2 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein NAD_binding_10 PF13460.6 ABK73951.1 - 4.6e-16 59.2 0.7 7.6e-16 58.5 0.7 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ABK73951.1 - 2.9e-11 43.3 0.1 6.6e-11 42.1 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 ABK73951.1 - 2.1e-08 34.0 0.0 4.2e-08 33.0 0.1 1.4 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.17 ABK73951.1 - 0.00073 18.7 0.0 0.0014 17.8 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 ABK73951.1 - 0.001 18.5 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 ABK73951.1 - 0.0029 17.9 0.0 0.18 12.1 0.0 2.3 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 ABK73951.1 - 0.0099 15.1 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 ABK73951.1 - 0.015 14.3 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 ABK73951.1 - 0.045 14.2 0.1 0.12 12.8 0.1 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.25 ABK73951.1 - 0.19 11.1 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase Polysacc_synt_2 PF02719.15 ABK73951.1 - 0.25 10.4 0.0 0.54 9.3 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DUF4190 PF13828.6 ABK73952.1 - 2.1e-16 59.4 13.6 3e-16 58.9 13.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4190) FxsA PF04186.13 ABK73952.1 - 1.9 8.7 8.2 0.84 9.8 0.6 2.1 2 0 0 2 2 2 0 FxsA cytoplasmic membrane protein Prominin PF05478.11 ABK73952.1 - 7.7 4.3 6.6 9.1 4.1 6.6 1.0 1 0 0 1 1 1 0 Prominin Beta-lactamase2 PF13354.6 ABK73953.1 - 4.5e-05 23.1 0.0 0.022 14.4 0.0 2.2 1 1 1 2 2 2 2 Beta-lactamase enzyme family Beta-lactamase PF00144.24 ABK73953.1 - 0.0017 17.7 1.1 0.0038 16.5 0.3 1.8 2 0 0 2 2 2 1 Beta-lactamase HD_4 PF13328.6 ABK73954.1 - 4.1e-46 156.6 1.2 8.9e-46 155.5 1.2 1.6 1 0 0 1 1 1 1 HD domain RelA_SpoT PF04607.17 ABK73954.1 - 1.6e-37 128.4 0.0 3.2e-37 127.4 0.0 1.5 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins TGS PF02824.21 ABK73954.1 - 3e-23 81.6 0.0 6.5e-23 80.5 0.0 1.6 1 0 0 1 1 1 1 TGS domain ACT_4 PF13291.6 ABK73954.1 - 1.1e-16 61.1 0.1 2.2e-16 60.2 0.1 1.5 1 0 0 1 1 1 1 ACT domain HD PF01966.22 ABK73954.1 - 7e-13 48.9 0.4 2e-12 47.4 0.4 1.9 1 0 0 1 1 1 1 HD domain ACT PF01842.25 ABK73954.1 - 4.3e-11 42.4 1.9 7.6e-11 41.6 0.4 2.4 3 0 0 3 3 3 1 ACT domain MiaE_2 PF13794.6 ABK73954.1 - 0.018 14.8 0.3 2.1 8.0 0.0 2.5 1 1 0 2 2 2 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like Ub-Mut7C PF14451.6 ABK73954.1 - 0.16 11.8 0.4 0.6 10.0 0.1 2.2 2 0 0 2 2 2 0 Mut7-C ubiquitin Exonuc_V_gamma PF04257.14 ABK73955.1 - 1.4e-204 681.6 0.0 1.6e-204 681.4 0.0 1.0 1 0 0 1 1 1 1 Exodeoxyribonuclease V, gamma subunit RecC_C PF17946.1 ABK73955.1 - 6e-45 153.5 0.5 5.1e-44 150.4 0.0 2.6 2 0 0 2 2 2 1 RecC C-terminal domain MR_MLE_C PF13378.6 ABK73956.1 - 8.5e-52 175.9 0.9 1.2e-51 175.4 0.9 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 ABK73956.1 - 8.8e-05 22.7 0.1 0.00066 19.9 0.1 2.3 1 1 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DUF429 PF04250.13 ABK73957.1 - 2.2e-36 125.6 2.4 4.3e-36 124.7 2.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF429) RelA_SpoT PF04607.17 ABK73957.1 - 3.1e-18 66.2 0.0 4.8e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins MHB PF16525.5 ABK73958.1 - 1.2e-34 118.4 0.0 1.7e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Haemophore, haem-binding DUF2469 PF10611.9 ABK73959.1 - 2e-52 175.9 3.1 2.2e-52 175.8 3.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2469) Response_reg PF00072.24 ABK73960.1 - 4.7e-10 39.6 0.3 6e-10 39.3 0.3 1.1 1 0 0 1 1 1 1 Response regulator receiver domain HHH_3 PF12836.7 ABK73962.1 - 9.1e-22 77.1 0.0 1.4e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 ABK73962.1 - 2.8e-14 52.1 0.2 3.7e-09 36.0 0.0 3.0 2 0 0 2 2 2 2 Helix-hairpin-helix motif SLBB PF10531.9 ABK73962.1 - 5.1e-10 39.1 0.6 1.1e-09 38.0 0.6 1.6 1 0 0 1 1 1 1 SLBB domain HHH_5 PF14520.6 ABK73962.1 - 1.2e-06 29.0 0.1 0.00074 20.1 0.0 2.4 1 1 1 2 2 2 2 Helix-hairpin-helix domain HHH_2 PF12826.7 ABK73962.1 - 2.8e-05 24.1 0.0 0.0027 17.8 0.0 2.6 1 1 1 2 2 2 1 Helix-hairpin-helix motif DUF1970 PF09301.10 ABK73962.1 - 0.0067 16.7 0.8 0.017 15.3 0.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1970) HHH_6 PF14579.6 ABK73962.1 - 0.0073 16.6 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif T2SSK PF03934.13 ABK73962.1 - 0.0098 15.3 0.4 1 8.7 0.0 2.8 2 1 1 3 3 3 1 Type II secretion system (T2SS), protein K HHH_8 PF14716.6 ABK73962.1 - 0.04 14.3 0.0 1.6 9.2 0.0 2.4 1 1 1 2 2 2 0 Helix-hairpin-helix domain Transposase_20 PF02371.16 ABK73962.1 - 0.081 13.2 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family PsbU PF06514.11 ABK73962.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Photosystem II 12 kDa extrinsic protein (PsbU) GTP1_OBG PF01018.22 ABK73963.1 - 8.8e-51 171.6 4.8 8.8e-51 171.6 4.8 1.6 2 0 0 2 2 2 1 GTP1/OBG DUF1967 PF09269.11 ABK73963.1 - 9e-26 89.6 0.0 1.4e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1967) MMR_HSR1 PF01926.23 ABK73963.1 - 1.5e-21 76.6 0.0 2.6e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ABK73963.1 - 2.1e-08 33.8 0.0 2.6e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Bac_luciferase PF00296.20 ABK73964.1 - 5e-54 183.9 0.6 5.9e-54 183.6 0.6 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF4491 PF14898.6 ABK73965.1 - 0.063 13.7 0.1 0.12 12.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4491) NVEALA PF14055.6 ABK73965.1 - 0.14 12.1 1.6 0.44 10.5 0.1 2.2 2 0 0 2 2 2 0 NVEALA protein LGT PF01790.18 ABK73965.1 - 0.19 10.9 5.9 0.11 11.7 2.6 1.8 1 1 1 2 2 2 0 Prolipoprotein diacylglyceryl transferase DUF1772 PF08592.11 ABK73965.1 - 2 8.7 11.6 0.46 10.8 7.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) DUF4131 PF13567.6 ABK73965.1 - 2.3 7.8 5.0 6.1 6.5 5.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF993 PF06187.11 ABK73966.1 - 6.1e-164 545.5 0.2 6.9e-164 545.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF993) T7SS_ESX1_EccB PF05108.13 ABK73967.1 - 1.9e-132 442.3 7.7 2.1e-132 442.2 7.7 1.0 1 0 0 1 1 1 1 Type VII secretion system ESX-1, transport TM domain B DUF732 PF05305.14 ABK73968.1 - 6.5e-24 84.1 5.6 1.6e-23 82.9 5.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF732) 3HCDH PF00725.22 ABK73968.1 - 0.074 13.7 0.1 0.12 13.0 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain PRCH PF03967.13 ABK73968.1 - 0.21 11.8 2.1 0.27 11.5 1.2 1.6 1 1 1 2 2 2 0 Photosynthetic reaction centre, H-chain N-terminal region DUF3662 PF12401.8 ABK73969.1 - 4.5e-38 130.2 0.0 6.1e-38 129.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2662) FHA PF00498.26 ABK73969.1 - 1.3e-16 60.7 0.0 2.1e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 ABK73969.1 - 6.9e-15 55.1 0.1 1.1e-14 54.5 0.1 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain CbiJ PF02571.14 ABK73970.1 - 3e-69 233.1 0.0 3.4e-69 232.9 0.0 1.0 1 0 0 1 1 1 1 Precorrin-6x reductase CbiJ/CobK ATPgrasp_N PF18130.1 ABK73970.1 - 0.0018 18.8 0.3 1.1 9.8 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp N-terminal domain Peripla_BP_4 PF13407.6 ABK73970.1 - 0.01 15.4 0.0 0.27 10.7 0.0 2.4 3 0 0 3 3 3 0 Periplasmic binding protein domain BPD_transp_1 PF00528.22 ABK73971.1 - 1e-17 64.5 19.6 1e-17 64.5 19.6 2.0 1 1 1 2 2 2 2 Binding-protein-dependent transport system inner membrane component DsbD PF02683.15 ABK73972.1 - 4.4e-43 147.7 15.6 5.7e-43 147.3 15.6 1.1 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region RimK PF08443.11 ABK73973.1 - 3e-12 46.5 0.0 1.8e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 RimK-like ATP-grasp domain Acetyltransf_1 PF00583.25 ABK73973.1 - 4e-11 43.2 0.0 2e-09 37.7 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family ATPgrasp_ST PF14397.6 ABK73973.1 - 6.9e-07 28.8 0.0 2.5e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp Acetyltransf_7 PF13508.7 ABK73973.1 - 8.3e-07 29.3 0.0 4e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ABK73973.1 - 1e-06 28.7 0.0 2.2e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GSH-S_ATP PF02955.16 ABK73973.1 - 1.3e-06 28.0 0.1 4e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 Prokaryotic glutathione synthetase, ATP-grasp domain FR47 PF08445.10 ABK73973.1 - 1.5e-06 28.1 0.0 3.8e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Dala_Dala_lig_C PF07478.13 ABK73973.1 - 3.7e-05 23.4 0.0 0.00099 18.7 0.0 2.3 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 ABK73973.1 - 0.00023 21.2 0.0 0.0089 16.1 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_YheCD PF14398.6 ABK73973.1 - 0.0023 17.3 0.0 0.037 13.3 0.0 2.3 2 1 0 2 2 2 1 YheC/D like ATP-grasp Acetyltransf_4 PF13420.7 ABK73973.1 - 0.0084 16.2 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain UBD PF16455.5 ABK73973.1 - 0.017 15.4 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-binding domain PAS_9 PF13426.7 ABK73973.1 - 0.019 15.2 0.0 0.071 13.4 0.0 2.0 1 0 0 1 1 1 0 PAS domain ATP-grasp_6 PF18419.1 ABK73973.1 - 0.028 14.1 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp-like domain Acetyltransf_6 PF13480.7 ABK73973.1 - 0.029 14.5 2.2 0.32 11.1 0.2 3.2 2 2 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ABK73973.1 - 0.042 14.5 0.0 0.29 11.8 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 ABK73974.1 - 9.9e-44 149.7 45.1 9.9e-44 149.7 45.1 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Iron_permease PF04120.12 ABK73974.1 - 0.1 12.4 0.8 0.26 11.1 0.1 2.0 2 0 0 2 2 2 0 Low affinity iron permease DUF3619 PF12279.8 ABK73974.1 - 1.3 9.4 4.6 11 6.3 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3619) GntR PF00392.21 ABK73975.1 - 2.1e-21 75.3 0.2 7e-21 73.7 0.1 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family UTRA PF07702.13 ABK73975.1 - 1.2e-17 64.1 0.0 2.1e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 UTRA domain HTH_41 PF14502.6 ABK73975.1 - 9.6e-05 22.0 0.0 0.00019 21.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Fe_dep_repress PF01325.19 ABK73975.1 - 0.00012 22.2 0.0 0.087 13.0 0.0 2.4 2 0 0 2 2 2 2 Iron dependent repressor, N-terminal DNA binding domain HTH_11 PF08279.12 ABK73975.1 - 0.00014 21.7 0.1 0.0039 17.1 0.0 3.0 3 0 0 3 3 3 1 HTH domain HTH_5 PF01022.20 ABK73975.1 - 0.00019 21.2 0.0 0.013 15.3 0.0 2.4 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 ABK73975.1 - 0.00031 20.6 0.1 0.0052 16.6 0.0 2.6 3 0 0 3 3 2 1 MarR family HTH_24 PF13412.6 ABK73975.1 - 0.00038 20.0 0.0 0.92 9.1 0.0 3.3 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding HTH_DeoR PF08220.12 ABK73975.1 - 0.0012 18.5 0.5 0.084 12.6 0.1 2.7 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain MarR PF01047.22 ABK73975.1 - 0.0099 15.8 0.0 0.42 10.6 0.0 2.4 2 0 0 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 ABK73975.1 - 0.0099 15.8 0.1 0.081 12.9 0.0 2.3 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain TrmB PF01978.19 ABK73975.1 - 0.014 15.3 0.0 0.036 14.0 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.7 ABK73975.1 - 0.014 15.4 0.2 0.24 11.5 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain TFIIE_alpha PF02002.17 ABK73975.1 - 0.021 14.7 0.0 0.37 10.7 0.0 2.4 2 0 0 2 2 2 0 TFIIE alpha subunit pXO2-72 PF17443.2 ABK73975.1 - 0.051 13.8 0.0 0.094 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein pXO2-72 HTH_17 PF12728.7 ABK73975.1 - 0.093 12.9 0.1 25 5.2 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain Rrf2 PF02082.20 ABK73975.1 - 0.16 12.4 0.0 0.43 11.0 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator HTH_AsnC-type PF13404.6 ABK73975.1 - 0.24 11.3 2.6 16 5.4 0.0 3.5 4 0 0 4 4 4 0 AsnC-type helix-turn-helix domain adh_short_C2 PF13561.6 ABK73976.1 - 9.9e-54 182.4 0.0 1.2e-53 182.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK73976.1 - 5.6e-35 120.6 0.0 9.6e-35 119.8 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 ABK73976.1 - 6.1e-08 32.4 0.0 2.7e-07 30.3 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ABK73976.1 - 0.021 14.2 0.2 0.037 13.4 0.0 1.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase KR PF08659.10 ABK73976.1 - 0.037 13.9 1.0 0.28 11.1 0.3 2.0 1 1 0 2 2 2 0 KR domain RmlD_sub_bind PF04321.17 ABK73976.1 - 0.057 12.5 0.1 0.08 12.0 0.1 1.4 1 1 0 1 1 1 0 RmlD substrate binding domain Phosphonate-bd PF12974.7 ABK73977.1 - 3.1e-60 203.8 0.0 3.6e-60 203.6 0.0 1.0 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 ABK73977.1 - 2.2e-06 27.3 0.0 0.0076 15.7 0.0 2.2 2 0 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.11 ABK73977.1 - 8e-06 25.9 0.0 1.9e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 NMT1/THI5 like PBP_like PF12727.7 ABK73977.1 - 0.021 13.9 0.0 0.037 13.2 0.0 1.4 1 0 0 1 1 1 0 PBP superfamily domain Transferrin PF00405.17 ABK73977.1 - 0.052 12.7 0.0 0.08 12.1 0.0 1.2 1 0 0 1 1 1 0 Transferrin Lipoprotein_9 PF03180.14 ABK73977.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 NLPA lipoprotein TetR_C_1 PF02909.17 ABK73978.1 - 3.2e-16 59.5 0.9 2.1e-12 47.1 0.1 2.2 1 1 1 2 2 2 2 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK73978.1 - 5.9e-15 54.8 0.3 3.5e-14 52.3 0.0 2.3 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family RsbRD_N PF14361.6 ABK73978.1 - 0.016 15.9 0.8 0.034 14.8 0.7 1.6 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain DUF768 PF05589.11 ABK73978.1 - 0.079 13.0 0.1 0.21 11.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF768) Abhydrolase_9_N PF15420.6 ABK73979.1 - 0.011 15.8 0.8 0.019 15.0 0.8 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus BsuPI PF12690.7 ABK73979.1 - 0.13 12.3 0.0 0.44 10.6 0.0 1.8 2 0 0 2 2 2 0 Intracellular proteinase inhibitor DUF2613 PF11021.8 ABK73979.1 - 0.19 11.8 6.2 0.59 10.3 6.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) TALPID3 PF15324.6 ABK73979.1 - 4.2 4.9 8.1 5.4 4.6 8.1 1.1 1 0 0 1 1 1 0 Hedgehog signalling target Glyoxalase PF00903.25 ABK73980.1 - 6.4e-11 42.5 0.0 8.1e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ABK73980.1 - 0.00054 20.7 0.0 0.00077 20.2 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 ABK73980.1 - 0.00068 19.9 0.0 0.41 11.0 0.0 2.3 1 1 1 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF294_C PF10335.9 ABK73981.1 - 1.2e-25 90.0 0.1 3.5e-25 88.5 0.0 1.7 2 0 0 2 2 2 1 Putative nucleotidyltransferase substrate binding domain DUF294 PF03445.13 ABK73981.1 - 1.9e-18 66.6 0.1 4e-18 65.5 0.0 1.6 2 0 0 2 2 2 1 Putative nucleotidyltransferase DUF294 NTP_transf_2 PF01909.23 ABK73981.1 - 0.00014 22.0 0.0 0.00049 20.3 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyltransferase domain ABC1 PF03109.16 ABK73982.1 - 9.8e-36 122.5 0.0 1.9e-35 121.6 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 ABK73982.1 - 2.1e-05 24.6 5.1 0.00011 22.2 2.7 2.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 ABK73982.1 - 0.00059 19.5 0.0 0.0017 18.0 0.0 1.7 2 0 0 2 2 2 1 RIO1 family CMAS PF02353.20 ABK73983.1 - 2.5e-108 361.5 0.2 2.8e-108 361.4 0.2 1.0 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 ABK73983.1 - 2.2e-08 34.7 0.0 4.7e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABK73983.1 - 1.1e-07 32.4 0.1 2.9e-07 31.1 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABK73983.1 - 6e-07 29.4 0.0 8.8e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK73983.1 - 2.7e-06 28.1 0.0 6.1e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ABK73983.1 - 0.00031 20.6 0.0 0.00047 20.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 ABK73983.1 - 0.0004 20.2 0.0 0.00065 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 ABK73983.1 - 0.0045 16.6 0.0 0.009 15.6 0.0 1.5 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 ABK73983.1 - 0.049 13.2 0.0 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_2 PF00891.18 ABK73983.1 - 0.051 12.9 0.0 0.11 11.7 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase domain Acetyltransf_13 PF13880.6 ABK73983.1 - 0.091 12.7 0.0 1.8 8.6 0.0 2.4 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase Methyltransf_32 PF13679.6 ABK73983.1 - 0.17 11.9 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 ABK73983.1 - 0.21 10.6 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase F_bP_aldolase PF01116.20 ABK73984.1 - 1.4e-79 267.5 0.5 1.6e-79 267.3 0.5 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Pyridox_ox_2 PF12900.7 ABK73984.1 - 0.0041 17.1 0.2 0.0041 17.1 0.2 2.0 2 1 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase DXP_reductoisom PF02670.16 ABK73985.1 - 5e-37 127.5 2.8 8.7e-37 126.7 2.8 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXP_redisom_C PF08436.12 ABK73985.1 - 3.7e-35 119.9 0.0 9e-35 118.7 0.0 1.7 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain DXPR_C PF13288.6 ABK73985.1 - 2.4e-33 114.8 0.0 5.3e-33 113.7 0.0 1.6 2 0 0 2 2 2 1 DXP reductoisomerase C-terminal domain Sacchrp_dh_NADP PF03435.18 ABK73985.1 - 0.031 14.5 0.7 0.19 12.0 0.7 2.2 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 ABK73985.1 - 0.1 12.0 0.1 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Calici_MSP PF05752.11 ABK73985.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Calicivirus minor structural protein Glycos_transf_1 PF00534.20 ABK73986.1 - 1.2e-14 54.2 0.0 2.2e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ABK73986.1 - 7e-12 45.9 0.4 1.7e-11 44.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ABK73986.1 - 4.1e-06 26.9 1.9 4.1e-06 26.9 1.9 2.0 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 ABK73986.1 - 0.00033 21.0 0.0 0.00091 19.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 FAD_binding_3 PF01494.19 ABK73987.1 - 3.1e-25 89.1 0.4 4.9e-25 88.5 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ABK73987.1 - 1.4e-06 28.2 2.5 0.00021 21.0 0.6 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ABK73987.1 - 1.9e-06 28.0 0.6 6e-06 26.4 0.6 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 ABK73987.1 - 4.5e-06 26.2 0.4 0.016 14.5 0.4 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 ABK73987.1 - 1.9e-05 24.0 3.2 2.1e-05 23.8 0.9 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 ABK73987.1 - 0.0001 21.7 0.8 0.0022 17.3 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ABK73987.1 - 0.00043 19.3 0.3 0.00043 19.3 0.3 1.8 3 0 0 3 3 3 1 Tryptophan halogenase Thi4 PF01946.17 ABK73987.1 - 0.0063 15.8 0.3 0.013 14.7 0.3 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 ABK73987.1 - 0.0071 15.1 0.1 0.024 13.4 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 ABK73987.1 - 0.008 15.5 0.2 0.075 12.3 0.6 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ABK73987.1 - 0.077 12.1 0.6 0.11 11.6 0.6 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 ABK73987.1 - 0.098 13.2 1.1 0.49 11.0 0.7 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ECH_1 PF00378.20 ABK73988.1 - 5.6e-48 163.4 0.0 6.7e-48 163.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK73988.1 - 1.5e-23 83.8 0.1 1.8e-23 83.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 2_5_RNA_ligase2 PF13563.6 ABK73989.1 - 1.7e-09 37.7 0.1 2.1e-09 37.5 0.1 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 ABK73989.1 - 0.004 17.3 0.9 0.8 9.9 0.0 2.4 2 1 0 2 2 2 2 LigT like Phosphoesterase SOBP PF15279.6 ABK73990.1 - 2.3 8.8 13.1 3.2 8.3 13.1 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein PGPGW PF09656.10 ABK73990.1 - 6.5 6.4 7.3 7.3 6.2 5.6 2.0 1 1 0 1 1 1 0 Putative transmembrane protein (PGPGW) VWA_CoxE PF05762.14 ABK73991.1 - 6e-55 186.0 0.5 1e-54 185.3 0.5 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein RmuC PF02646.16 ABK73991.1 - 0.08 12.1 0.1 0.13 11.3 0.1 1.3 1 0 0 1 1 1 0 RmuC family Fmp27_WPPW PF10359.9 ABK73991.1 - 0.23 10.3 0.6 0.33 9.7 0.6 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TetR_C_15 PF17918.1 ABK73991.1 - 1.6 9.5 9.1 8 7.3 0.0 4.4 4 1 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain FliT PF05400.13 ABK73991.1 - 5.6 7.9 10.7 0.92 10.4 0.1 3.4 3 0 0 3 3 3 0 Flagellar protein FliT MCD_N PF17408.2 ABK73991.1 - 5.6 7.2 6.7 0.65 10.2 0.7 2.5 3 0 0 3 3 3 0 Malonyl-CoA decarboxylase N-terminal domain RraA-like PF03737.15 ABK73992.1 - 1.6e-33 116.0 7.4 1.9e-33 115.7 7.4 1.1 1 0 0 1 1 1 1 Aldolase/RraA Trp_halogenase PF04820.14 ABK73993.1 - 4.3e-11 42.3 0.0 0.0002 20.4 0.0 3.1 3 0 0 3 3 3 2 Tryptophan halogenase DAO PF01266.24 ABK73993.1 - 0.00012 21.8 0.3 0.0054 16.3 0.3 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ABK73993.1 - 0.00052 19.3 0.1 0.061 12.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ABK73993.1 - 0.00065 19.0 0.6 0.16 11.2 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ABK73993.1 - 0.013 15.7 0.0 0.032 14.5 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ABK73993.1 - 0.051 14.1 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ABK73993.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 ABK73993.1 - 0.14 10.8 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Histidinol_dh PF00815.20 ABK73994.1 - 2.8e-155 517.3 5.2 3.2e-155 517.2 5.2 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase DUF4523 PF15023.6 ABK73994.1 - 0.14 12.0 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) HNH_3 PF13392.6 ABK73995.1 - 1.9e-09 37.1 0.5 3.1e-09 36.4 0.5 1.3 1 0 0 1 1 1 1 HNH endonuclease HNH PF01844.23 ABK73995.1 - 0.021 15.0 1.2 0.054 13.7 1.2 1.8 1 1 0 1 1 1 0 HNH endonuclease PDZ_1 PF12812.7 ABK73995.1 - 0.034 14.2 0.0 0.042 13.9 0.0 1.1 1 0 0 1 1 1 0 PDZ-like domain Endonuclease_7 PF02945.15 ABK73995.1 - 0.055 13.4 0.6 0.11 12.4 0.6 1.5 1 1 0 1 1 1 0 Recombination endonuclease VII Maf PF02545.14 ABK73995.1 - 0.11 12.4 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Maf-like protein NinE PF05322.11 ABK73995.1 - 0.12 12.3 0.6 0.22 11.4 0.6 1.4 1 0 0 1 1 1 0 NINE Protein Zn_Tnp_IS1595 PF12760.7 ABK73995.1 - 0.27 11.2 0.3 0.27 11.2 0.3 2.5 3 0 0 3 3 3 0 Transposase zinc-ribbon domain zf-C2H2_12 PF18658.1 ABK73995.1 - 0.31 10.7 1.2 17 5.0 0.2 2.2 1 1 1 2 2 2 0 Zinc-finger C2H2-type MFS_1 PF07690.16 ABK73996.1 - 2.3e-29 102.4 62.2 1.5e-15 57.0 31.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK73996.1 - 1.1e-25 90.4 37.7 2.7e-21 76.0 10.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter FHA PF00498.26 ABK73997.1 - 2.2e-19 69.6 0.0 2.9e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 ABK73997.1 - 2.7e-18 66.1 0.0 3.6e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain ADH_N PF08240.12 ABK73998.1 - 5.6e-33 113.1 1.1 8.6e-33 112.5 1.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ABK73998.1 - 7.6e-14 51.8 0.0 1.3e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ABK73998.1 - 1.2e-05 24.9 0.3 2.8e-05 23.7 0.2 1.7 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N_assoc PF13823.6 ABK73998.1 - 0.021 14.7 0.3 0.053 13.5 0.0 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-associated Cyclase PF04199.13 ABK73999.1 - 1.2e-23 83.8 0.1 3e-23 82.5 0.0 1.6 1 1 0 2 2 2 1 Putative cyclase Bac_luciferase PF00296.20 ABK74000.1 - 2.3e-50 171.8 8.9 7.3e-50 170.2 8.9 1.7 1 1 0 1 1 1 1 Luciferase-like monooxygenase HATPase_c PF02518.26 ABK74001.1 - 1.5e-07 31.9 0.1 3e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 ABK74001.1 - 0.00043 20.2 0.0 0.00084 19.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HisKA_3 PF07730.13 ABK74001.1 - 0.0045 17.5 2.7 0.0045 17.5 2.7 2.9 3 0 0 3 3 3 1 Histidine kinase HATPase_c_3 PF13589.6 ABK74001.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Bax1-I PF01027.20 ABK74001.1 - 1.7 8.4 12.0 3 7.6 12.0 1.4 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 FUR PF01475.19 ABK74002.1 - 5.8e-19 68.4 0.0 7.2e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Ferric uptake regulator family HTH_27 PF13463.6 ABK74002.1 - 0.065 13.7 0.0 0.1 13.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain Nudix_N_2 PF14803.6 ABK74002.1 - 0.15 12.0 4.1 0.19 11.7 0.5 2.5 2 0 0 2 2 2 0 Nudix N-terminal CHAT PF12770.7 ABK74003.1 - 1.9e-12 47.2 0.3 3.7e-12 46.2 0.3 1.5 1 1 0 1 1 1 1 CHAT domain Acyl-CoA_dh_1 PF00441.24 ABK74004.1 - 4.1e-16 59.5 5.6 1e-15 58.3 5.6 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK74004.1 - 0.00063 20.4 0.7 0.0022 18.6 0.7 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Phage-tail_1 PF09097.10 ABK74004.1 - 0.089 12.6 0.0 0.19 11.5 0.0 1.6 2 0 0 2 2 2 0 Baseplate structural protein, domain 1 AMP-binding PF00501.28 ABK74005.1 - 1.8e-184 613.2 0.1 1.8e-93 313.5 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 ABK74005.1 - 3e-151 504.2 0.0 4.2e-76 256.5 0.0 3.2 3 0 0 3 3 3 3 Condensation domain AMP-binding_C PF13193.6 ABK74005.1 - 2.8e-12 47.4 0.2 3.7e-09 37.4 0.0 3.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 ABK74005.1 - 1.9e-11 44.2 0.1 8.9e-11 42.0 0.1 2.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site LnmK_N_HDF PF18238.1 ABK74005.1 - 0.13 12.0 0.0 11 5.7 0.0 2.5 2 0 0 2 2 2 0 LnmK N-terminal Hot Dog Fold domain Aldolase_II PF00596.21 ABK74006.1 - 2.6e-50 170.9 0.3 3e-50 170.7 0.3 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain SBP_bac_11 PF13531.6 ABK74007.1 - 5.9e-13 49.1 6.5 5.9e-13 49.1 6.5 1.7 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein VWA_2 PF13519.6 ABK74007.1 - 0.021 15.5 0.0 0.066 13.9 0.0 1.9 1 0 0 1 1 1 0 von Willebrand factor type A domain VWA PF00092.28 ABK74007.1 - 0.054 13.8 0.0 0.094 13.0 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain Tad PF13400.6 ABK74007.1 - 1.7 9.0 6.6 3.1 8.2 5.3 2.1 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like PASTA PF03793.19 ABK74008.1 - 0.023 14.5 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 PASTA domain DUF2000 PF09391.10 ABK74008.1 - 0.04 13.8 0.2 0.065 13.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2000) ABC_tran PF00005.27 ABK74009.1 - 8e-59 198.1 0.0 1.3e-30 106.7 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ABK74009.1 - 1.9e-15 57.5 7.5 3.2e-06 27.2 0.0 4.1 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system oligo_HPY PF08352.12 ABK74009.1 - 9e-14 51.7 0.0 1.5e-07 31.8 0.0 2.4 2 0 0 2 2 2 2 Oligopeptide/dipeptide transporter, C-terminal region AAA_29 PF13555.6 ABK74009.1 - 2.5e-07 30.3 0.7 0.015 15.0 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 ABK74009.1 - 1.9e-06 28.2 4.8 0.054 13.8 0.4 3.6 2 2 0 2 2 2 2 AAA domain SMC_N PF02463.19 ABK74009.1 - 1.9e-06 27.5 3.9 0.033 13.6 0.9 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ABK74009.1 - 3.4e-06 27.5 5.6 0.012 16.0 0.1 2.9 2 2 0 2 2 2 2 AAA ATPase domain Mg_chelatase PF01078.21 ABK74009.1 - 0.00011 21.6 0.1 0.25 10.7 0.0 3.0 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 ABK74009.1 - 0.00014 21.8 0.4 0.079 12.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 ABK74009.1 - 0.00037 21.1 0.0 0.5 10.8 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 ABK74009.1 - 0.00048 19.9 0.7 0.45 10.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 ABK74009.1 - 0.00058 20.0 4.1 0.0095 16.0 0.3 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_33 PF13671.6 ABK74009.1 - 0.00069 19.8 2.9 0.19 11.9 0.3 3.0 3 1 0 3 3 2 1 AAA domain PRK PF00485.18 ABK74009.1 - 0.00074 19.3 0.0 0.38 10.5 0.0 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_5 PF07728.14 ABK74009.1 - 0.0019 18.2 1.3 2.2 8.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 ABK74009.1 - 0.0019 18.4 0.9 2.1 8.6 0.1 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 ABK74009.1 - 0.0059 16.5 0.0 0.91 9.4 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain T2SSE PF00437.20 ABK74009.1 - 0.011 14.9 0.5 4 6.4 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.12 ABK74009.1 - 0.012 15.5 1.8 4.1 7.3 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 ABK74009.1 - 0.014 15.8 3.2 8.2 6.9 0.1 3.6 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 ABK74009.1 - 0.016 14.7 0.6 4.6 6.7 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 ABK74009.1 - 0.025 13.9 1.3 2.1 7.7 0.0 2.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_18 PF13238.6 ABK74009.1 - 0.028 15.0 0.2 4 8.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ABK74009.1 - 0.046 13.3 0.8 14 5.2 0.0 3.0 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.12 ABK74009.1 - 0.047 13.0 1.5 3.7 6.8 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin IstB_IS21 PF01695.17 ABK74009.1 - 0.05 13.3 0.9 3.1 7.5 0.0 2.8 3 0 0 3 3 2 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 ABK74009.1 - 0.052 13.3 3.7 3.2 7.4 0.0 3.4 4 0 0 4 4 3 0 Sigma-54 interaction domain MMR_HSR1 PF01926.23 ABK74009.1 - 0.064 13.3 1.3 2.5 8.2 0.1 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase G-alpha PF00503.20 ABK74009.1 - 0.08 12.1 0.0 6.9 5.7 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit ATPase PF06745.13 ABK74009.1 - 0.083 12.2 1.0 8.7 5.6 0.1 2.5 2 0 0 2 2 2 0 KaiC NB-ARC PF00931.22 ABK74009.1 - 0.094 11.9 0.8 3.1 6.9 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain TsaE PF02367.17 ABK74009.1 - 0.096 12.7 0.2 5.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 ABK74009.1 - 0.1 12.3 9.5 0.96 9.1 0.5 3.1 3 1 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.25 ABK74009.1 - 0.12 12.0 0.3 1.2 8.7 0.1 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.22 ABK74009.1 - 0.15 12.5 0.5 8.6 6.8 0.1 2.4 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.15 ABK74009.1 - 0.15 11.9 2.0 1.4 8.8 0.1 2.5 2 0 0 2 2 2 0 NTPase MobB PF03205.14 ABK74009.1 - 0.15 11.9 0.6 3 7.7 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AIG1 PF04548.16 ABK74009.1 - 0.17 11.2 3.1 1.5 8.1 0.4 2.2 2 0 0 2 2 2 0 AIG1 family TrwB_AAD_bind PF10412.9 ABK74009.1 - 0.23 10.3 0.6 5 5.9 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain APS_kinase PF01583.20 ABK74009.1 - 0.24 11.3 0.9 18 5.2 0.1 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_19 PF13245.6 ABK74009.1 - 0.26 11.6 1.8 6.1 7.2 0.1 2.6 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.22 ABK74009.1 - 0.29 10.7 4.6 3.7 7.1 0.1 2.8 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Pox_A32 PF04665.12 ABK74009.1 - 0.44 10.0 2.8 7 6.0 0.1 2.7 3 0 0 3 3 3 0 Poxvirus A32 protein CbiA PF01656.23 ABK74009.1 - 2.1 8.4 4.0 35 4.4 0.5 2.9 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short_C2 PF13561.6 ABK74010.1 - 2.8e-60 203.8 0.9 3.2e-60 203.6 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK74010.1 - 4.3e-50 169.9 0.0 5e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK74010.1 - 3.6e-11 43.3 0.1 5e-11 42.8 0.1 1.2 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 ABK74010.1 - 0.019 15.0 0.9 1.7 8.7 0.4 2.3 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Epimerase PF01370.21 ABK74010.1 - 0.052 13.0 0.6 0.29 10.5 0.6 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 ABK74010.1 - 0.11 13.0 0.2 0.68 10.4 0.2 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding FecCD PF01032.18 ABK74012.1 - 1.1e-97 326.9 39.1 1.3e-97 326.6 39.1 1.1 1 0 0 1 1 1 1 FecCD transport family ABC-3 PF00950.17 ABK74012.1 - 6.6 6.1 29.8 0.047 13.2 20.6 2.1 2 1 0 2 2 2 0 ABC 3 transport family adh_short PF00106.25 ABK74014.1 - 2.6e-26 92.3 0.3 3.6e-26 91.8 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK74014.1 - 2.1e-16 60.2 2.8 2.7e-16 59.9 2.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK74014.1 - 7.5e-10 39.0 1.4 1.1e-09 38.5 1.4 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 ABK74016.1 - 1.8e-37 129.1 0.3 2.4e-37 128.7 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK74016.1 - 5e-32 110.9 0.0 6.6e-32 110.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK74016.1 - 1.5e-13 51.1 0.2 2.5e-13 50.3 0.2 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 ABK74016.1 - 0.00018 21.7 0.0 0.00036 20.8 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 ABK74016.1 - 0.00076 19.0 0.0 0.0015 18.0 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family ThiF PF00899.21 ABK74016.1 - 0.097 12.0 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.20 ABK74016.1 - 0.17 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 ABK74016.1 - 0.17 11.0 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein CheR PF01739.18 ABK74017.1 - 4.7e-53 179.6 0.0 8.1e-53 178.8 0.0 1.4 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain PAS_9 PF13426.7 ABK74017.1 - 2.5e-16 59.8 0.1 4.1e-09 36.6 0.0 2.9 3 0 0 3 3 2 2 PAS domain PAS PF00989.25 ABK74017.1 - 4.1e-16 59.0 3.3 1.2e-07 31.7 0.0 3.3 3 1 0 3 3 2 2 PAS fold CheR_N PF03705.15 ABK74017.1 - 6.1e-15 54.7 1.1 1.2e-14 53.8 1.1 1.5 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain PAS_10 PF13596.6 ABK74017.1 - 2.3e-13 50.7 0.0 2.2e-06 28.2 0.0 3.0 3 1 0 3 3 2 2 PAS domain PAS_4 PF08448.10 ABK74017.1 - 3.2e-13 49.9 1.2 3.3e-05 24.1 0.2 2.7 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 ABK74017.1 - 1.6e-10 40.7 0.1 0.0002 21.3 0.0 2.9 2 0 0 2 2 2 2 PAS domain PAS_7 PF12860.7 ABK74017.1 - 2.4e-06 27.7 2.3 0.00035 20.7 0.0 3.8 3 1 1 4 4 3 1 PAS fold Spc7 PF08317.11 ABK74017.1 - 1.9e-05 23.7 9.5 3e-05 23.0 9.5 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein HOOK PF05622.12 ABK74017.1 - 6e-05 21.4 5.6 8.6e-05 20.9 5.6 1.1 1 0 0 1 1 1 1 HOOK protein PAS_3 PF08447.12 ABK74017.1 - 7e-05 23.0 0.0 0.73 10.2 0.0 2.8 2 0 0 2 2 2 2 PAS fold DUF3450 PF11932.8 ABK74017.1 - 0.00023 20.6 8.2 0.00044 19.6 6.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) DUF1664 PF07889.12 ABK74017.1 - 0.00023 21.2 3.9 0.00051 20.1 3.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.11 ABK74017.1 - 0.00025 21.5 10.9 0.00031 21.2 8.6 2.3 2 0 0 2 2 1 1 Syntaxin 6, N-terminal Methyltransf_12 PF08242.12 ABK74017.1 - 0.00059 20.5 0.1 0.0092 16.7 0.0 2.8 2 1 0 2 2 1 1 Methyltransferase domain HIP1_clath_bdg PF16515.5 ABK74017.1 - 0.00073 20.1 9.9 0.0019 18.7 9.9 1.8 1 0 0 1 1 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4795 PF16043.5 ABK74017.1 - 0.00074 19.2 5.7 0.0015 18.2 5.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) HMMR_N PF15905.5 ABK74017.1 - 0.00084 18.9 8.6 0.0012 18.4 8.6 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal OmpH PF03938.14 ABK74017.1 - 0.00098 19.5 2.0 0.0021 18.4 2.0 1.5 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) APG17 PF04108.12 ABK74017.1 - 0.001 18.3 3.7 0.0018 17.4 3.7 1.4 1 0 0 1 1 1 1 Autophagy protein Apg17 KxDL PF10241.9 ABK74017.1 - 0.0012 19.1 5.4 0.0039 17.4 4.8 2.1 2 0 0 2 2 1 1 Uncharacterized conserved protein WEMBL PF05701.11 ABK74017.1 - 0.0018 17.1 7.5 0.0027 16.5 7.5 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Tropomyosin PF00261.20 ABK74017.1 - 0.002 17.5 12.1 0.0032 16.9 12.1 1.2 1 0 0 1 1 1 1 Tropomyosin Rootletin PF15035.6 ABK74017.1 - 0.0021 18.1 5.2 0.0038 17.3 5.2 1.4 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Jnk-SapK_ap_N PF09744.9 ABK74017.1 - 0.0021 18.3 10.5 0.004 17.4 10.5 1.4 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 DUF4618 PF15397.6 ABK74017.1 - 0.0028 17.1 5.5 0.0051 16.3 5.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) Fez1 PF06818.15 ABK74017.1 - 0.0031 18.0 6.5 0.0055 17.2 6.5 1.3 1 0 0 1 1 1 1 Fez1 TMPIT PF07851.13 ABK74017.1 - 0.0034 16.7 5.0 0.0052 16.1 5.0 1.2 1 0 0 1 1 1 1 TMPIT-like protein ZapB PF06005.12 ABK74017.1 - 0.0035 17.8 20.0 0.23 11.9 11.0 2.4 1 1 1 2 2 2 2 Cell division protein ZapB IFT57 PF10498.9 ABK74017.1 - 0.0037 16.3 9.7 0.0059 15.6 9.7 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 UPF0449 PF15136.6 ABK74017.1 - 0.0037 17.7 12.8 0.021 15.3 3.1 2.5 1 1 1 2 2 2 1 Uncharacterised protein family UPF0449 KASH_CCD PF14662.6 ABK74017.1 - 0.0039 17.1 9.9 0.007 16.2 9.9 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH HemX PF04375.14 ABK74017.1 - 0.0046 16.3 4.0 0.0071 15.7 4.0 1.2 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase TPR_MLP1_2 PF07926.12 ABK74017.1 - 0.0051 16.9 14.7 0.0095 16.0 14.7 1.4 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein DUF2203 PF09969.9 ABK74017.1 - 0.0066 17.2 3.6 0.015 16.0 3.6 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2203) FapA PF03961.13 ABK74017.1 - 0.0095 14.6 1.7 0.013 14.1 1.7 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A DASH_Duo1 PF08651.10 ABK74017.1 - 0.0099 15.6 9.9 0.068 13.0 4.4 2.5 1 1 1 2 2 2 2 DASH complex subunit Duo1 WXG100 PF06013.12 ABK74017.1 - 0.01 16.0 4.8 0.18 12.0 4.7 2.6 1 1 0 1 1 1 0 Proteins of 100 residues with WXG DUF724 PF05266.14 ABK74017.1 - 0.01 15.7 4.1 0.017 14.9 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ADIP PF11559.8 ABK74017.1 - 0.011 15.8 11.9 0.02 15.0 11.9 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding UPF0242 PF06785.11 ABK74017.1 - 0.011 15.8 6.5 0.018 15.1 6.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 ABK74017.1 - 0.011 15.3 1.6 0.019 14.5 1.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 ABK74017.1 - 0.013 14.7 3.9 0.021 13.9 3.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3584 PF12128.8 ABK74017.1 - 0.013 13.0 6.6 0.019 12.5 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HALZ PF02183.18 ABK74017.1 - 0.014 15.6 1.4 0.014 15.6 1.4 2.6 1 1 1 2 2 2 0 Homeobox associated leucine zipper RPW8 PF05659.11 ABK74017.1 - 0.017 14.8 2.4 0.032 13.9 2.4 1.4 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 LMBR1 PF04791.16 ABK74017.1 - 0.018 14.0 0.8 0.033 13.1 0.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein MCPsignal PF00015.21 ABK74017.1 - 0.02 14.7 4.0 0.046 13.5 4.0 1.5 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Golgin_A5 PF09787.9 ABK74017.1 - 0.021 14.3 12.4 0.035 13.6 12.4 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Filament PF00038.21 ABK74017.1 - 0.022 14.4 9.5 0.04 13.5 9.5 1.3 1 0 0 1 1 1 0 Intermediate filament protein DUF5089 PF17002.5 ABK74017.1 - 0.023 14.6 7.1 0.047 13.6 6.4 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF5089) AAA_23 PF13476.6 ABK74017.1 - 0.023 15.2 2.5 0.043 14.3 2.5 1.5 1 0 0 1 1 1 0 AAA domain MCC-bdg_PDZ PF10506.9 ABK74017.1 - 0.024 14.7 11.0 0.62 10.1 2.9 3.7 2 1 2 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome TMF_TATA_bd PF12325.8 ABK74017.1 - 0.025 14.8 14.0 0.047 13.9 14.0 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding ATG16 PF08614.11 ABK74017.1 - 0.033 14.4 12.4 0.06 13.6 12.4 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4446 PF14584.6 ABK74017.1 - 0.034 14.1 1.6 0.071 13.1 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) MLTR_LBD PF17765.1 ABK74017.1 - 0.034 14.3 3.4 2.9 8.0 0.0 3.8 4 0 0 4 4 2 0 MmyB-like transcription regulator ligand binding domain HNOBA PF07701.14 ABK74017.1 - 0.036 13.5 0.3 0.036 13.5 0.3 2.4 1 1 1 2 2 2 0 Heme NO binding associated GAS PF13851.6 ABK74017.1 - 0.036 13.4 9.5 0.062 12.6 9.5 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding EzrA PF06160.12 ABK74017.1 - 0.048 11.9 8.0 0.069 11.3 8.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Seryl_tRNA_N PF02403.22 ABK74017.1 - 0.049 13.8 8.2 0.1 12.8 8.2 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain bZIP_1 PF00170.21 ABK74017.1 - 0.053 13.6 13.7 0.1 12.7 7.5 2.7 1 1 2 3 3 3 0 bZIP transcription factor HAUS-augmin3 PF14932.6 ABK74017.1 - 0.057 13.0 8.3 0.1 12.2 8.3 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF812 PF05667.11 ABK74017.1 - 0.068 12.0 6.3 0.1 11.5 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Fmp27_WPPW PF10359.9 ABK74017.1 - 0.082 11.7 5.7 0.12 11.2 5.7 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Laminin_II PF06009.12 ABK74017.1 - 0.089 12.8 9.9 0.3 11.1 9.9 1.9 1 1 0 1 1 1 0 Laminin Domain II DUF3540 PF12059.8 ABK74017.1 - 0.089 12.6 0.4 0.22 11.3 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3540) DivIC PF04977.15 ABK74017.1 - 0.097 12.5 12.6 0.15 11.8 5.6 2.7 1 1 1 2 2 2 0 Septum formation initiator APG6_N PF17675.1 ABK74017.1 - 0.099 13.2 15.9 0.066 13.7 13.9 1.7 2 0 0 2 2 1 0 Apg6 coiled-coil region Methyltransf_25 PF13649.6 ABK74017.1 - 0.099 13.4 0.1 13 6.6 0.1 3.4 2 1 0 2 2 1 0 Methyltransferase domain zf-C4H2 PF10146.9 ABK74017.1 - 0.1 12.9 8.3 0.15 12.3 8.3 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein DUF16 PF01519.16 ABK74017.1 - 0.1 13.1 5.3 0.25 11.9 5.3 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF16 Cluap1 PF10234.9 ABK74017.1 - 0.11 11.9 6.3 0.18 11.2 6.3 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 STAT_alpha PF01017.20 ABK74017.1 - 0.12 12.2 5.8 0.26 11.2 5.8 1.5 1 0 0 1 1 1 0 STAT protein, all-alpha domain Ax_dynein_light PF10211.9 ABK74017.1 - 0.13 12.2 8.4 0.26 11.2 8.4 1.5 1 0 0 1 1 1 0 Axonemal dynein light chain DLP_helical PF18709.1 ABK74017.1 - 0.13 11.4 6.0 0.2 10.8 4.7 1.8 2 0 0 2 2 2 0 Dynamin-like helical domain Snapin_Pallidin PF14712.6 ABK74017.1 - 0.14 12.5 5.2 0.34 11.4 5.2 1.6 1 0 0 1 1 1 0 Snapin/Pallidin CALCOCO1 PF07888.11 ABK74017.1 - 0.15 10.9 10.7 0.04 12.8 7.7 1.5 2 0 0 2 2 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4200 PF13863.6 ABK74017.1 - 0.15 12.4 13.1 2 8.9 8.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) V_ATPase_I PF01496.19 ABK74017.1 - 0.15 9.9 2.9 0.21 9.5 2.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4140 PF13600.6 ABK74017.1 - 0.21 12.0 5.7 36 4.9 5.7 2.9 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) NPV_P10 PF05531.12 ABK74017.1 - 0.21 12.0 9.7 0.13 12.7 5.4 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein JIP_LZII PF16471.5 ABK74017.1 - 0.25 11.5 19.1 14 5.9 0.0 2.8 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II HrpB7 PF09486.10 ABK74017.1 - 0.27 11.6 5.9 1.6 9.1 6.0 2.3 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Tweety PF04906.13 ABK74017.1 - 0.27 9.9 1.3 0.45 9.1 1.3 1.3 1 0 0 1 1 1 0 Tweety COG2 PF06148.11 ABK74017.1 - 0.28 11.3 8.2 2.2 8.4 2.8 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Mod_r PF07200.13 ABK74017.1 - 0.3 11.2 11.5 0.23 11.5 9.3 1.9 2 0 0 2 2 1 0 Modifier of rudimentary (Mod(r)) protein Phage_GP20 PF06810.11 ABK74017.1 - 0.34 10.7 8.6 0.72 9.6 8.6 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 GIT_CC PF16559.5 ABK74017.1 - 0.38 10.7 13.7 2.9 7.8 1.7 2.9 2 1 1 3 3 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor CENP-F_leu_zip PF10473.9 ABK74017.1 - 0.41 10.7 17.0 1.9 8.5 17.2 2.0 2 1 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DHR10 PF18595.1 ABK74017.1 - 0.43 10.6 15.4 1.9 8.6 15.1 2.0 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Flagellin_N PF00669.20 ABK74017.1 - 0.44 10.7 7.9 0.45 10.6 6.4 1.7 2 0 0 2 2 1 0 Bacterial flagellin N-terminal helical region Tropomyosin_1 PF12718.7 ABK74017.1 - 0.45 10.7 15.4 0.79 9.9 15.4 1.3 1 0 0 1 1 1 0 Tropomyosin like DUF3552 PF12072.8 ABK74017.1 - 0.45 9.9 9.5 0.77 9.1 9.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) CENP-H PF05837.12 ABK74017.1 - 0.46 10.9 10.0 0.89 10.0 10.0 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) FlaC_arch PF05377.11 ABK74017.1 - 0.59 10.6 13.3 3.8 8.0 3.3 2.7 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Mt_ATP-synt_D PF05873.12 ABK74017.1 - 0.59 10.0 2.2 1 9.2 2.2 1.3 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) DASH_Dam1 PF08653.10 ABK74017.1 - 0.62 9.9 7.2 1.8 8.4 2.3 2.8 1 1 1 2 2 2 0 DASH complex subunit Dam1 Occludin_ELL PF07303.13 ABK74017.1 - 0.62 10.8 3.4 1.1 10.0 2.7 1.8 2 0 0 2 2 1 0 Occludin homology domain Prominin PF05478.11 ABK74017.1 - 0.79 7.6 5.1 1.2 7.0 5.1 1.1 1 0 0 1 1 1 0 Prominin Sec34 PF04136.15 ABK74017.1 - 0.8 9.6 7.6 1.7 8.5 7.6 1.5 1 0 0 1 1 1 0 Sec34-like family DUF745 PF05335.13 ABK74017.1 - 0.8 9.4 7.3 1.5 8.5 7.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) PCRF PF03462.18 ABK74017.1 - 0.88 9.4 6.0 1.6 8.6 6.0 1.4 1 0 0 1 1 1 0 PCRF domain Fzo_mitofusin PF04799.13 ABK74017.1 - 0.97 9.0 5.3 1.7 8.1 5.3 1.4 1 0 0 1 1 1 0 fzo-like conserved region Cep57_CLD_2 PF14197.6 ABK74017.1 - 0.97 9.6 17.2 0.53 10.4 3.6 2.4 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 BLOC1_2 PF10046.9 ABK74017.1 - 1.1 9.6 12.3 4.5 7.6 12.3 1.9 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Wtap PF17098.5 ABK74017.1 - 1.1 9.1 13.8 2.8 7.8 13.6 1.8 1 1 0 1 1 1 0 WTAP/Mum2p family CorA PF01544.18 ABK74017.1 - 1.2 8.3 7.1 0.65 9.2 3.8 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein KfrA_N PF11740.8 ABK74017.1 - 1.3 9.7 12.6 10 6.9 9.1 2.8 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term Prefoldin_3 PF13758.6 ABK74017.1 - 1.7 8.7 7.8 0.42 10.7 2.4 2.3 1 1 1 2 2 2 0 Prefoldin subunit AATF-Che1 PF13339.6 ABK74017.1 - 1.8 9.2 5.9 2.2 8.9 4.7 1.7 2 0 0 2 2 1 0 Apoptosis antagonizing transcription factor Sec20 PF03908.13 ABK74017.1 - 1.9 8.5 8.8 2.1 8.3 6.4 2.2 2 1 1 3 3 2 0 Sec20 CC2-LZ PF16516.5 ABK74017.1 - 1.9 8.9 10.4 8.7 6.8 4.6 2.5 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator bZIP_2 PF07716.15 ABK74017.1 - 4.1 7.5 16.8 3.1 8.0 4.7 3.2 1 1 2 3 3 3 0 Basic region leucine zipper FliD_N PF02465.18 ABK74017.1 - 4.6 8.0 7.7 18 6.1 7.7 2.0 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus DUF948 PF06103.11 ABK74017.1 - 4.7 7.5 8.6 19 5.6 8.5 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) KELK PF15796.5 ABK74017.1 - 5.2 7.6 11.8 14 6.3 11.7 1.8 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Prefoldin_2 PF01920.20 ABK74017.1 - 6 6.9 14.9 91 3.1 14.8 2.4 1 1 0 1 1 1 0 Prefoldin subunit YabA PF06156.13 ABK74017.1 - 6.1 7.5 12.5 62 4.3 12.5 2.2 1 1 0 1 1 1 0 Initiation control protein YabA TMF_DNA_bd PF12329.8 ABK74017.1 - 6.3 6.9 15.8 14 5.8 15.6 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Swi5 PF07061.11 ABK74017.1 - 7 6.8 11.6 2.1 8.5 7.0 2.2 1 1 1 2 2 2 0 Swi5 DivIVA PF05103.13 ABK74017.1 - 9.1 6.4 12.1 18 5.4 3.9 2.2 1 1 1 2 2 2 0 DivIVA protein Lpp-LpqN PF10738.9 ABK74018.1 - 4e-59 199.0 0.0 5.4e-59 198.5 0.0 1.2 1 0 0 1 1 1 1 Probable lipoprotein LpqN Acyl-CoA_dh_1 PF00441.24 ABK74019.1 - 5.8e-39 133.7 0.4 4.4e-38 130.8 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK74019.1 - 8.3e-25 87.7 0.4 1.8e-24 86.6 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ABK74019.1 - 3.1e-19 69.0 0.0 5.3e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ABK74019.1 - 3.5e-18 66.2 0.6 7e-18 65.2 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain SecA_DEAD PF07517.14 ABK74020.1 - 6.3e-131 435.9 0.2 1e-130 435.3 0.2 1.3 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_SW PF07516.13 ABK74020.1 - 1.2e-67 227.9 2.9 2.5e-67 226.8 2.9 1.6 1 0 0 1 1 1 1 SecA Wing and Scaffold domain SecA_PP_bind PF01043.20 ABK74020.1 - 1.4e-35 122.3 0.2 4.4e-35 120.7 0.2 1.9 1 0 0 1 1 1 1 SecA preprotein cross-linking domain DEAD PF00270.29 ABK74020.1 - 0.0083 15.9 0.0 0.025 14.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ABK74020.1 - 0.021 15.2 1.0 0.31 11.4 0.0 3.0 3 0 0 3 3 3 0 Helicase conserved C-terminal domain DUF4497 PF14924.6 ABK74020.1 - 0.12 12.9 0.0 0.28 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4497) Fer2_BFD PF04324.15 ABK74021.1 - 1.7e-09 37.8 5.9 2.4e-09 37.4 5.9 1.2 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain LysR_substrate PF03466.20 ABK74022.1 - 1e-31 109.9 7.9 1e-31 109.9 7.9 1.6 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 ABK74022.1 - 1.2e-11 44.3 2.3 1.2e-11 44.3 2.3 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_5 PF01022.20 ABK74022.1 - 0.00038 20.3 0.3 0.00075 19.3 0.3 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 ABK74022.1 - 0.0062 16.4 0.4 0.034 14.1 0.1 2.4 2 0 0 2 2 2 1 MarR family HTH_Tnp_ISL3 PF13542.6 ABK74022.1 - 0.01 15.2 0.1 0.033 13.6 0.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_30 PF13556.6 ABK74022.1 - 0.011 15.6 0.3 0.026 14.3 0.3 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_23 PF13384.6 ABK74022.1 - 0.012 15.3 0.0 0.037 13.8 0.0 1.8 2 0 0 2 2 2 0 Homeodomain-like domain HTH_24 PF13412.6 ABK74022.1 - 0.023 14.3 0.1 0.055 13.0 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 ABK74022.1 - 0.044 13.9 0.0 0.17 12.1 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain Fe_dep_repress PF01325.19 ABK74022.1 - 0.11 12.8 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_50 PF18024.1 ABK74022.1 - 0.12 12.0 0.1 0.36 10.5 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain P22_Cro PF14549.6 ABK74022.1 - 0.19 11.6 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro MlaD PF02470.20 ABK74023.1 - 1.9e-16 60.1 0.8 3.4e-16 59.3 0.8 1.4 1 0 0 1 1 1 1 MlaD protein Mce4_CUP1 PF11887.8 ABK74023.1 - 6.4e-06 25.8 1.9 4.3e-05 23.1 1.9 2.0 1 1 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative DUF948 PF06103.11 ABK74023.1 - 0.00087 19.5 0.2 0.92 9.8 0.0 3.3 2 1 1 3 3 3 1 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 ABK74023.1 - 0.0068 16.4 3.7 0.76 9.8 0.3 2.3 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Sec34 PF04136.15 ABK74023.1 - 0.026 14.4 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 Sec34-like family EzrA PF06160.12 ABK74023.1 - 0.16 10.1 0.0 2.8 6.0 0.0 1.8 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF4164 PF13747.6 ABK74023.1 - 0.16 12.2 6.1 0.24 11.7 2.8 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) DHR10 PF18595.1 ABK74023.1 - 0.17 11.9 0.8 3.8 7.6 0.2 2.2 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain CdvA PF18822.1 ABK74023.1 - 0.18 11.6 0.1 5.9 6.7 0.0 2.7 1 1 1 2 2 2 0 CdvA-like coiled-coil domain FUSC PF04632.12 ABK74023.1 - 0.21 10.1 4.0 0.32 9.5 4.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Flagellin_N PF00669.20 ABK74023.1 - 0.35 11.0 3.0 0.86 9.7 2.7 1.7 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region NPV_P10 PF05531.12 ABK74023.1 - 0.58 10.7 3.1 9.6 6.8 0.2 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein FliT PF05400.13 ABK74023.1 - 9.9 7.1 7.9 14 6.5 4.1 2.7 1 1 2 3 3 3 0 Flagellar protein FliT adh_short_C2 PF13561.6 ABK74024.1 - 2.4e-58 197.5 0.0 3.1e-58 197.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK74024.1 - 1e-45 155.6 0.0 1.2e-45 155.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK74024.1 - 2.7e-07 30.7 0.0 3.7e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 KR domain LDcluster4 PF18306.1 ABK74024.1 - 0.035 13.7 0.1 0.055 13.1 0.1 1.3 1 0 0 1 1 1 0 SLOG cluster4 family SpoIIM PF01944.17 ABK74025.1 - 1.3e-34 119.5 8.2 1.9e-34 118.9 8.2 1.2 1 0 0 1 1 1 1 Stage II sporulation protein M PSD5 PF07637.11 ABK74025.1 - 0.089 13.2 0.2 0.25 11.7 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1595) DUF992 PF06186.11 ABK74025.1 - 0.16 11.8 1.9 0.14 12.0 0.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF992) ADH_zinc_N_2 PF13602.6 ABK74026.1 - 4.8e-15 56.8 0.0 1e-14 55.7 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ABK74026.1 - 9.4e-12 45.0 0.0 2.8e-11 43.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ABK74026.1 - 3.1e-06 27.0 1.3 0.00014 21.7 0.6 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.6 ABK74026.1 - 0.0097 15.8 0.1 0.017 15.0 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ABK74026.1 - 0.045 13.2 0.0 0.065 12.7 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 ABK74026.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase PASTA PF03793.19 ABK74027.1 - 1.3e-51 172.3 7.2 2.9e-16 59.1 0.6 4.3 4 0 0 4 4 4 4 PASTA domain Pkinase PF00069.25 ABK74027.1 - 3.4e-50 170.9 0.0 4.3e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ABK74027.1 - 1.6e-35 122.7 0.0 2.2e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ABK74027.1 - 2.3e-06 27.7 4.2 0.01 15.8 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ABK74027.1 - 0.00012 21.0 0.0 0.00018 20.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase LytR_C PF13399.6 ABK74027.1 - 0.0012 19.8 2.8 8 7.5 0.0 4.1 2 1 1 3 3 3 1 LytR cell envelope-related transcriptional attenuator DUF442 PF04273.13 ABK74027.1 - 0.0044 17.1 0.1 0.32 11.1 0.1 2.8 3 0 0 3 3 3 1 Putative phosphatase (DUF442) WaaY PF06176.11 ABK74027.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.22 ABK74027.1 - 0.024 14.2 0.1 0.045 13.3 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 ABK74027.1 - 0.024 13.7 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 ABK74027.1 - 0.22 10.9 0.0 0.38 10.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FGGY_N PF00370.21 ABK74028.1 - 1.7e-38 132.6 0.0 2.1e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 ABK74028.1 - 0.0017 17.9 0.2 0.0017 17.9 0.2 2.1 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family FGGY_C PF02782.16 ABK74028.1 - 0.11 12.2 5.5 0.028 14.1 2.1 1.7 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Peptidase_S58 PF03576.14 ABK74029.1 - 1.7e-109 365.9 7.8 2e-109 365.7 7.8 1.0 1 0 0 1 1 1 1 Peptidase family S58 AadA_C PF18280.1 ABK74029.1 - 0.014 15.6 0.0 0.051 13.7 0.0 1.9 2 0 0 2 2 2 0 Aminoglycoside adenyltransferase C-terminal domain FAD_binding_4 PF01565.23 ABK74030.1 - 5.1e-11 42.5 0.1 7.5e-11 41.9 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain PepSY_2 PF13670.6 ABK74031.1 - 0.081 12.9 0.8 0.12 12.4 0.8 1.2 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain ATP-synt_ab PF00006.25 ABK74032.1 - 4.2e-62 209.6 0.0 6.4e-62 209.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 ABK74032.1 - 2.6e-22 79.1 0.2 7.1e-22 77.7 0.2 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain T3SS_ATPase_C PF18269.1 ABK74032.1 - 0.0027 17.5 1.5 0.015 15.1 1.5 2.1 1 1 0 1 1 1 1 T3SS EscN ATPase C-terminal domain AAA_19 PF13245.6 ABK74032.1 - 0.005 17.2 0.6 0.15 12.4 0.2 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ABK74032.1 - 0.0066 16.4 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 ABK74032.1 - 0.011 16.2 0.0 0.18 12.2 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ABK74032.1 - 0.013 15.9 1.1 0.098 13.0 0.2 2.6 2 1 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 ABK74032.1 - 0.014 15.0 0.0 0.034 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 ABK74032.1 - 0.053 12.7 0.1 0.11 11.6 0.1 1.5 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 ABK74032.1 - 0.055 13.4 0.3 0.3 11.0 0.0 2.3 2 1 0 2 2 2 0 NACHT domain ATPase_2 PF01637.18 ABK74032.1 - 0.068 13.1 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 ABK74032.1 - 0.097 12.9 0.0 0.4 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 ABK74032.1 - 0.1 12.0 0.2 0.34 10.2 0.1 1.9 2 0 0 2 2 2 0 KaiC RNA_helicase PF00910.22 ABK74032.1 - 0.1 13.0 0.0 0.31 11.5 0.0 1.8 2 0 0 2 2 1 0 RNA helicase TsaE PF02367.17 ABK74032.1 - 0.17 11.9 0.1 0.35 10.9 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 ABK74032.1 - 0.21 11.1 0.0 0.47 9.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region LRV_FeS PF05484.11 ABK74032.1 - 0.24 11.4 0.1 0.48 10.5 0.1 1.5 1 0 0 1 1 1 0 LRV protein FeS4 cluster DJ-1_PfpI PF01965.24 ABK74033.1 - 4.4e-27 94.9 0.0 5.9e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 ABK74033.1 - 0.18 11.4 0.0 0.32 10.6 0.0 1.4 1 1 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 ABK74033.1 - 0.22 11.3 0.0 0.55 10.0 0.0 1.5 1 1 0 2 2 2 0 Glutamine amidotransferase class-I GAF PF01590.26 ABK74034.1 - 1e-07 32.6 0.0 1.3e-07 32.3 0.0 1.1 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 ABK74034.1 - 2.9e-07 30.9 0.1 3.5e-07 30.6 0.1 1.1 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 ABK74034.1 - 0.017 15.5 0.0 0.029 14.7 0.0 1.5 1 1 0 1 1 1 0 GAF domain AMP-binding PF00501.28 ABK74035.1 - 1e-71 241.8 0.0 1.2e-71 241.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme EHN PF06441.12 ABK74036.1 - 1.2e-31 109.3 0.4 2.2e-31 108.4 0.0 1.6 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 ABK74036.1 - 2.8e-15 56.7 0.2 4.6e-15 56.0 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK74036.1 - 2.6e-06 28.2 9.0 2.6e-06 28.2 9.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Dioxygenase_C PF00775.21 ABK74037.1 - 1e-57 194.5 0.1 1.2e-57 194.2 0.1 1.1 1 0 0 1 1 1 1 Dioxygenase PCDO_beta_N PF12391.8 ABK74037.1 - 8.5e-12 44.5 1.6 8.5e-12 44.5 1.6 2.1 2 0 0 2 2 2 1 Protocatechuate 3,4-dioxygenase beta subunit N terminal CarboxypepD_reg PF13620.6 ABK74037.1 - 4.5e-06 26.8 0.0 1.1e-05 25.5 0.0 1.7 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 ABK74037.1 - 0.17 12.1 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 SdrD B-like domain Big_1 PF02369.16 ABK74037.1 - 0.18 11.8 0.2 2.8 8.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) HxlR PF01638.17 ABK74038.1 - 1.4e-15 56.9 0.0 1.8e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_20 PF12840.7 ABK74038.1 - 0.023 14.8 0.1 0.056 13.5 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain MOSC PF03473.17 ABK74039.1 - 2.1e-22 79.5 0.0 3e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 MOSC domain BtpA PF03437.15 ABK74041.1 - 1.6e-80 270.2 0.7 1.9e-80 270.0 0.7 1.0 1 0 0 1 1 1 1 BtpA family PcrB PF01884.17 ABK74041.1 - 0.065 12.7 0.2 0.3 10.5 0.1 2.0 2 0 0 2 2 2 0 PcrB family FecCD PF01032.18 ABK74043.1 - 2.8e-89 299.2 36.3 3.7e-89 298.8 36.3 1.0 1 0 0 1 1 1 1 FecCD transport family ABC-3 PF00950.17 ABK74043.1 - 2e-05 24.3 24.6 4.1e-05 23.2 24.6 1.6 1 1 0 1 1 1 1 ABC 3 transport family Peptidase_M20 PF01546.28 ABK74044.1 - 1.6e-36 126.0 0.8 2.2e-36 125.5 0.8 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ABK74044.1 - 2.2e-16 59.7 0.0 4.1e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 ABK74044.1 - 0.0083 15.8 0.0 0.029 14.1 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 Methyltransf_23 PF13489.6 ABK74045.1 - 2.2e-15 56.9 0.0 2.7e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABK74045.1 - 1.7e-13 51.0 0.0 2.6e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABK74045.1 - 3.3e-12 46.9 0.0 5.2e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK74045.1 - 1.6e-10 41.6 0.0 2.3e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABK74045.1 - 1.8e-08 34.3 0.0 2.4e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ABK74045.1 - 0.00033 20.5 0.0 0.00044 20.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.11 ABK74045.1 - 0.013 15.2 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Bmt2 PF11968.8 ABK74045.1 - 0.041 13.7 0.0 0.068 13.0 0.0 1.3 1 0 0 1 1 1 0 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Ubie_methyltran PF01209.18 ABK74045.1 - 0.073 12.4 0.0 0.095 12.0 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family RrnaAD PF00398.20 ABK74045.1 - 0.17 10.9 0.0 0.23 10.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DAO PF01266.24 ABK74046.1 - 2.8e-44 152.1 8.6 4.8e-44 151.4 8.6 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ABK74046.1 - 3e-05 23.3 1.7 3.7e-05 23.0 0.6 1.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ABK74046.1 - 0.014 15.6 0.7 0.033 14.4 0.7 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 ABK74046.1 - 0.054 12.8 0.5 0.074 12.4 0.5 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 ABK74046.1 - 0.11 12.4 0.2 0.16 11.8 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HATPase_c PF02518.26 ABK74047.1 - 3.6e-19 69.3 0.0 9.2e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ABK74047.1 - 6.1e-10 39.0 0.9 2.1e-09 37.3 0.9 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 ABK74047.1 - 5.9e-06 26.6 11.1 6.5e-05 23.2 0.2 4.2 3 1 0 3 3 3 1 HAMP domain HATPase_c_2 PF13581.6 ABK74047.1 - 1.7e-05 24.8 0.3 6.1e-05 23.0 0.3 2.0 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 ABK74047.1 - 0.0016 18.3 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BLOC1S3 PF15753.5 ABK74047.1 - 0.23 11.6 1.4 6.3 6.9 0.1 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 ketoacyl-synt PF00109.26 ABK74048.1 - 5.6e-41 140.8 0.3 3.6e-40 138.1 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 ABK74048.1 - 1.6e-28 99.1 0.2 2.8e-28 98.3 0.2 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 ABK74048.1 - 2.5e-06 27.1 0.8 7.8e-05 22.1 0.3 2.6 2 1 1 3 3 3 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ABK74048.1 - 0.06 13.0 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Thiolase, C-terminal domain TetR_N PF00440.23 ABK74049.1 - 1.5e-08 34.3 0.1 2.6e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 ABK74049.1 - 0.00048 20.4 0.8 0.0018 18.6 0.1 2.1 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_29 PF17938.1 ABK74049.1 - 0.014 15.5 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TetR_C_27 PF17935.1 ABK74049.1 - 0.044 13.8 0.1 0.15 12.2 0.0 1.8 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TetR_C_24 PF17932.1 ABK74049.1 - 0.065 13.5 0.1 0.24 11.7 0.0 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Ribosomal_L18p PF00861.22 ABK74050.1 - 5.4e-45 152.5 5.5 6.4e-45 152.3 5.5 1.0 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast LPD30 PF18850.1 ABK74050.1 - 0.0043 16.8 0.1 0.0094 15.7 0.1 1.5 1 1 0 1 1 1 1 Large polyvalent protein associated domain 30 Vir_act_alpha_C PF10400.9 ABK74051.1 - 3.4e-21 75.7 1.3 3.4e-21 75.7 1.3 1.6 2 0 0 2 2 2 1 Virulence activator alpha C-term PadR PF03551.14 ABK74051.1 - 8.9e-16 57.6 0.0 1.3e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family Replic_Relax PF13814.6 ABK74051.1 - 0.00095 19.3 0.3 0.0026 17.8 0.1 1.6 1 1 1 2 2 2 1 Replication-relaxation AphA_like PF14557.6 ABK74051.1 - 0.0025 17.5 0.4 0.0035 17.1 0.4 1.2 1 0 0 1 1 1 1 Putative AphA-like transcriptional regulator HxlR PF01638.17 ABK74051.1 - 0.0042 16.9 0.0 0.0078 16.0 0.0 1.4 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_34 PF13601.6 ABK74051.1 - 0.0056 16.8 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain DUF4364 PF14277.6 ABK74051.1 - 0.0061 16.3 0.0 0.013 15.2 0.0 1.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4364) DUF505 PF04458.12 ABK74051.1 - 0.037 12.4 0.0 0.052 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF505) HTH_32 PF13565.6 ABK74051.1 - 0.12 13.0 8.3 0.052 14.2 1.8 3.0 2 1 0 2 2 2 0 Homeodomain-like domain ACT_7 PF13840.6 ABK74052.1 - 1.3e-17 63.3 0.1 1.6e-17 63.0 0.1 1.1 1 0 0 1 1 1 1 ACT domain ACT PF01842.25 ABK74052.1 - 0.0015 18.2 0.1 0.0024 17.6 0.1 1.4 1 0 0 1 1 1 1 ACT domain rve_3 PF13683.6 ABK74053.1 - 2.6e-11 43.1 1.1 3.4e-11 42.8 1.1 1.1 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 ABK74053.1 - 0.007 16.5 0.0 0.01 16.0 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain AveC_like PF17198.4 ABK74054.1 - 5.8e-101 336.8 5.5 9.1e-101 336.2 5.5 1.3 1 0 0 1 1 1 1 Spirocyclase AveC-like Lipoprotein_21 PF14041.6 ABK74055.1 - 3.9e-24 84.6 0.2 5.2e-24 84.2 0.2 1.2 1 0 0 1 1 1 1 LppP/LprE lipoprotein RcnB PF11776.8 ABK74055.1 - 0.054 13.6 0.2 0.56 10.3 0.0 2.6 2 0 0 2 2 2 0 Nickel/cobalt transporter regulator Abhydrolase_1 PF00561.20 ABK74056.1 - 3.3e-24 85.9 0.4 1.7e-23 83.6 0.4 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK74056.1 - 7.2e-15 56.2 9.4 8.6e-15 55.9 9.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK74056.1 - 0.00043 19.6 0.0 0.0033 16.7 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ham1p_like PF01725.16 ABK74057.1 - 8.7e-58 195.3 0.0 9.7e-58 195.2 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Sugar-bind PF04198.13 ABK74058.1 - 2.5e-41 141.5 0.0 3.9e-41 140.9 0.0 1.4 1 0 0 1 1 1 1 Putative sugar-binding domain HTH_Crp_2 PF13545.6 ABK74058.1 - 4.3e-07 29.8 0.0 8.4e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 ABK74058.1 - 7.2e-07 29.0 0.5 3.7e-06 26.7 0.1 2.3 2 0 0 2 2 2 1 MarR family Sigma70_r4 PF04545.16 ABK74058.1 - 1.1e-06 28.0 0.3 2e-06 27.2 0.3 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 ABK74058.1 - 0.00011 21.9 0.1 0.00039 20.1 0.1 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 ABK74058.1 - 0.00015 21.5 0.6 0.00042 20.0 0.3 1.9 2 0 0 2 2 1 1 Homeodomain-like domain HTH_24 PF13412.6 ABK74058.1 - 0.00017 21.1 0.0 0.00028 20.4 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 ABK74058.1 - 0.00086 19.1 0.1 0.0025 17.6 0.1 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain Sigma70_r4_2 PF08281.12 ABK74058.1 - 0.0035 17.0 0.4 0.0085 15.7 0.4 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 TrmB PF01978.19 ABK74058.1 - 0.0043 16.9 0.2 0.018 14.9 0.1 2.0 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_28 PF13518.6 ABK74058.1 - 0.006 16.7 0.4 0.017 15.2 0.4 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 ABK74058.1 - 0.01 16.2 0.1 0.01 16.2 0.1 1.9 2 0 0 2 2 1 0 Helix-turn-helix domain MarR PF01047.22 ABK74058.1 - 0.011 15.7 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_3 PF01381.22 ABK74058.1 - 0.012 15.6 0.1 0.026 14.6 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix HTH_Tnp_ISL3 PF13542.6 ABK74058.1 - 0.018 14.4 0.1 0.054 12.9 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Rrf2 PF02082.20 ABK74058.1 - 0.026 14.9 0.1 0.1 12.9 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator HTH_36 PF13730.6 ABK74058.1 - 0.039 13.9 0.0 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 ABK74058.1 - 0.042 13.9 0.1 0.14 12.2 0.1 1.9 1 0 0 1 1 1 0 Winged helix-turn helix DUF134 PF02001.16 ABK74058.1 - 0.057 14.0 0.0 0.15 12.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF134 HTH_37 PF13744.6 ABK74058.1 - 0.064 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain GntR PF00392.21 ABK74058.1 - 0.076 12.7 0.9 0.22 11.2 0.9 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family LacI PF00356.21 ABK74058.1 - 0.091 12.6 0.1 0.23 11.3 0.1 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family YdaS_antitoxin PF15943.5 ABK74058.1 - 0.12 12.3 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_40 PF14493.6 ABK74058.1 - 0.18 12.3 0.0 0.35 11.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain MFS_1 PF07690.16 ABK74059.1 - 1.2e-31 109.9 46.2 1.2e-31 109.9 46.2 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.8 ABK74059.1 - 0.013 14.2 0.2 0.013 14.2 0.2 2.8 3 0 0 3 3 3 0 Vacuole effluxer Atg22 like MTES_1575 PF18741.1 ABK74060.1 - 7.6e-10 38.8 0.1 5.6e-09 36.1 0.1 2.0 2 0 0 2 2 2 1 REase_MTES_1575 DUF559 PF04480.12 ABK74060.1 - 0.0003 20.6 0.0 0.00053 19.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF559) AbiEi_4 PF13338.6 ABK74060.1 - 0.001 19.2 0.7 0.0031 17.6 0.0 2.3 2 0 0 2 2 2 1 Transcriptional regulator, AbiEi antitoxin DUF2726 PF10881.8 ABK74060.1 - 0.12 12.2 0.0 7 6.6 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2726) Response_reg PF00072.24 ABK74061.1 - 7.8e-24 84.0 0.0 1.5e-23 83.1 0.0 1.5 2 0 0 2 2 2 1 Response regulator receiver domain GerE PF00196.19 ABK74061.1 - 4.9e-16 58.0 0.0 8.9e-16 57.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 ABK74061.1 - 1.3e-06 28.0 0.1 2.6e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 ABK74061.1 - 0.00023 20.9 0.0 0.00053 19.7 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_30 PF13556.6 ABK74061.1 - 0.00066 19.4 0.0 0.0016 18.2 0.0 1.7 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_40 PF14493.6 ABK74061.1 - 0.0035 17.8 0.0 0.0066 16.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 ABK74061.1 - 0.0041 16.6 0.0 0.008 15.7 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 ABK74061.1 - 0.0047 17.0 0.0 0.018 15.1 0.0 2.0 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_1 PF00126.27 ABK74061.1 - 0.0066 16.4 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family DUF742 PF05331.11 ABK74061.1 - 0.026 14.3 1.9 0.036 13.9 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF742) HTH_20 PF12840.7 ABK74061.1 - 0.04 14.0 0.8 0.2 11.8 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.7 ABK74061.1 - 0.041 13.8 0.1 0.21 11.5 0.1 2.2 1 1 1 2 2 2 0 MarR family Penicillinase_R PF03965.16 ABK74061.1 - 0.044 14.1 0.0 0.21 11.9 0.0 2.1 2 1 0 2 2 2 0 Penicillinase repressor HTH_7 PF02796.15 ABK74061.1 - 0.13 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase PMT_2 PF13231.6 ABK74062.1 - 1.7e-13 51.1 9.8 1.7e-13 51.1 9.8 2.5 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase HATPase_c PF02518.26 ABK74063.1 - 3.8e-26 91.8 0.0 8.3e-26 90.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ABK74063.1 - 1.3e-13 50.7 0.1 3e-13 49.6 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 ABK74063.1 - 3.1e-05 23.8 0.1 6.5e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 ABK74063.1 - 0.0056 16.6 0.6 0.053 13.5 0.1 2.7 2 1 0 2 2 2 1 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 ABK74063.1 - 0.069 13.1 0.0 0.16 11.9 0.0 1.6 1 1 0 1 1 1 0 GHKL domain DUF1421 PF07223.11 ABK74063.1 - 0.28 11.1 2.0 9.8 6.1 0.1 2.9 2 1 1 3 3 3 0 UBA-like domain (DUF1421) FdhD-NarQ PF02634.15 ABK74066.1 - 2.3e-84 282.8 0.1 2.6e-84 282.6 0.1 1.0 1 0 0 1 1 1 1 FdhD/NarQ family DUF305 PF03713.13 ABK74067.1 - 1.4e-50 171.3 12.8 2.2e-50 170.7 12.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF305) DUF4142 PF13628.6 ABK74067.1 - 0.0012 19.1 7.3 0.021 15.0 1.8 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4142) DUF3558 PF12079.8 ABK74067.1 - 0.0091 16.0 0.8 0.014 15.4 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3558) FCD PF07729.12 ABK74068.1 - 1.8e-18 67.1 7.7 1.8e-18 67.1 7.7 1.7 2 0 0 2 2 2 1 FCD domain GntR PF00392.21 ABK74068.1 - 8.8e-16 57.3 0.5 2.4e-15 55.9 0.5 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family TrmB PF01978.19 ABK74068.1 - 0.021 14.7 0.1 0.041 13.8 0.1 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB TFIIE_alpha PF02002.17 ABK74068.1 - 0.027 14.3 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 TFIIE alpha subunit HTH_24 PF13412.6 ABK74068.1 - 0.093 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Rrf2 PF02082.20 ABK74068.1 - 0.16 12.3 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator PaaX PF07848.12 ABK74068.1 - 0.59 10.4 2.3 0.61 10.3 0.1 2.1 3 0 0 3 3 3 0 PaaX-like protein TPM_phosphatase PF04536.14 ABK74069.1 - 1.3e-18 67.3 0.3 2.8e-18 66.3 0.3 1.6 1 0 0 1 1 1 1 TPM domain Stevor PF17410.2 ABK74069.1 - 0.0051 16.4 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame DUF4381 PF14316.6 ABK74069.1 - 0.024 14.9 0.1 0.024 14.9 0.1 3.6 3 1 0 4 4 4 0 Domain of unknown function (DUF4381) BatA PF07584.11 ABK74069.1 - 0.053 13.9 0.2 0.2 12.1 0.2 2.0 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal ABC_tran_CTD PF16326.5 ABK74069.1 - 0.06 13.6 11.0 0.9 9.8 0.1 4.3 3 2 0 3 3 3 0 ABC transporter C-terminal domain Phage_holin_2_4 PF16082.5 ABK74069.1 - 0.081 12.7 0.3 0.081 12.7 0.3 2.7 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like BRE1 PF08647.11 ABK74069.1 - 0.098 12.7 3.0 0.13 12.3 0.2 2.5 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase Phage_holin_3_6 PF07332.11 ABK74069.1 - 0.2 11.7 0.1 0.2 11.7 0.1 3.3 4 0 0 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III DUF1664 PF07889.12 ABK74069.1 - 0.22 11.6 2.0 10 6.2 0.4 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) CcmD PF04995.14 ABK74069.1 - 0.46 10.6 6.0 0.1 12.7 0.9 2.7 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) AAA_13 PF13166.6 ABK74069.1 - 1.1 7.9 7.6 0.64 8.6 0.3 2.5 2 1 1 3 3 3 0 AAA domain NPV_P10 PF05531.12 ABK74069.1 - 2.9 8.4 9.9 0.75 10.3 0.2 3.6 4 1 0 4 4 3 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.9 ABK74069.1 - 3 6.8 4.3 9.3 5.2 0.1 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 GMC_oxred_C PF05199.13 ABK74069.1 - 3.4 8.2 7.6 6.7 7.2 0.9 3.4 1 1 1 2 2 2 0 GMC oxidoreductase PTR2 PF00854.21 ABK74070.1 - 2.6e-54 184.6 13.4 2.6e-54 184.6 13.4 1.6 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 ABK74070.1 - 6.1e-15 55.0 61.6 1.3e-08 34.1 47.6 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily PalH PF08733.10 ABK74070.1 - 2.5 7.0 10.6 5.3 6.0 10.6 1.5 1 0 0 1 1 1 0 PalH/RIM21 PmbA_TldD PF01523.16 ABK74071.1 - 6.6e-31 108.2 0.0 1.1e-30 107.5 0.0 1.2 1 0 0 1 1 1 1 Putative modulator of DNA gyrase Aldo_ket_red PF00248.21 ABK74072.1 - 7.8e-56 189.4 0.0 9.7e-56 189.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CobW_C PF07683.14 ABK74073.1 - 1.9e-13 50.2 0.1 5.1e-13 48.8 0.1 1.8 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain cobW PF02492.19 ABK74073.1 - 1.6e-09 37.6 0.0 2.6e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain DUF692 PF05114.13 ABK74074.1 - 2.8e-80 269.3 0.0 3.3e-80 269.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF692) NAD_binding_1 PF00175.21 ABK74076.1 - 3.1e-12 47.1 0.0 6.4e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 ABK74076.1 - 5.4e-09 36.3 0.0 1e-08 35.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 ABK74076.1 - 0.00032 20.9 0.0 0.017 15.2 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Fer2 PF00111.27 ABK74076.1 - 0.0013 18.7 0.4 0.0025 17.7 0.4 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Desulfoferrod_N PF06397.12 ABK74077.1 - 0.014 15.0 2.0 2.3 7.9 0.4 2.6 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain T7SS_ESX_EspC PF10824.8 ABK74079.1 - 0.00086 19.7 1.9 0.0011 19.4 1.9 1.1 1 0 0 1 1 1 1 Excreted virulence factor EspC, type VII ESX diderm DUF3742 PF12553.8 ABK74080.1 - 0.026 14.6 0.9 0.034 14.3 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) DLH PF01738.18 ABK74081.1 - 5.9e-39 133.9 0.0 8.1e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 ABK74081.1 - 1.3e-06 27.9 0.1 5.6e-05 22.5 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ABK74081.1 - 0.0034 17.1 0.0 0.0053 16.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ABK74081.1 - 0.0052 16.3 0.0 0.0098 15.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF5572 PF17733.1 ABK74082.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5572) Sigma70_r4_2 PF08281.12 ABK74083.1 - 1.5e-13 50.2 0.0 2.5e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 ABK74083.1 - 1.1e-08 34.4 0.0 2.2e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 ABK74083.1 - 1.5e-06 27.8 0.5 4.2e-06 26.4 0.5 1.7 1 0 0 1 1 1 1 Sigma-70 region 2 SnoaL_2 PF12680.7 ABK74083.1 - 5.8e-05 23.7 0.3 0.00024 21.7 0.0 2.3 2 1 0 2 2 2 1 SnoaL-like domain DUF4440 PF14534.6 ABK74083.1 - 0.0016 18.8 0.0 0.0042 17.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 ABK74083.1 - 0.018 15.3 0.0 0.037 14.3 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain RNase_T PF00929.24 ABK74084.1 - 1.8e-34 119.6 0.0 3.3e-34 118.8 0.0 1.4 1 0 0 1 1 1 1 Exonuclease GIY-YIG PF01541.24 ABK74084.1 - 0.00019 21.6 0.0 0.00031 21.0 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain DUF5051 PF16473.5 ABK74084.1 - 0.013 15.5 0.0 0.033 14.2 0.0 1.8 1 1 0 1 1 1 0 3' exoribonuclease, RNase T-like UVR PF02151.19 ABK74084.1 - 0.054 13.3 0.7 0.12 12.2 0.7 1.5 1 0 0 1 1 1 0 UvrB/uvrC motif Beta-lactamase2 PF13354.6 ABK74085.1 - 0.13 11.9 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 Beta-lactamase enzyme family DNA_pol3_finger PF17657.1 ABK74085.1 - 0.13 11.6 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha subunit finger domain HTH_6 PF01418.17 ABK74086.1 - 1.1e-15 57.4 0.0 2.2e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family MarR_2 PF12802.7 ABK74086.1 - 7.6e-05 22.5 0.3 0.00015 21.6 0.3 1.5 1 0 0 1 1 1 1 MarR family SIS PF01380.22 ABK74086.1 - 0.00018 21.4 0.0 0.00027 20.8 0.0 1.2 1 0 0 1 1 1 1 SIS domain HTH_Crp_2 PF13545.6 ABK74086.1 - 0.0018 18.2 0.0 0.0031 17.5 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR PF01047.22 ABK74086.1 - 0.078 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 MarR family Transketolase_N PF00456.21 ABK74088.1 - 6.5e-43 147.0 0.0 1.3e-42 146.0 0.0 1.4 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 ABK74088.1 - 4.2e-31 108.0 2.2 7.7e-31 107.1 2.2 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ABK74088.1 - 4e-28 97.8 1.5 1.1e-27 96.4 0.2 2.1 2 0 0 2 2 2 1 Transketolase, C-terminal domain E1_dh PF00676.20 ABK74088.1 - 1.8e-07 30.4 0.0 3.1e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 ABK74088.1 - 3.4e-06 26.5 0.0 0.00086 18.6 0.0 2.7 2 1 0 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 ABK74088.1 - 4.2e-06 26.6 4.2 1.4e-05 24.9 0.4 3.0 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF460 PF04312.13 ABK74088.1 - 0.038 13.7 0.0 0.099 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF460) ABC2_membrane_3 PF12698.7 ABK74090.1 - 0.006 15.7 12.7 0.024 13.8 0.0 2.2 2 0 0 2 2 2 1 ABC-2 family transporter protein Trypsin_2 PF13365.6 ABK74091.1 - 1e-35 123.9 5.6 2.9e-35 122.4 5.6 1.8 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 ABK74091.1 - 5e-17 62.0 1.7 1.2e-16 60.8 1.7 1.7 1 0 0 1 1 1 1 PDZ domain Trypsin PF00089.26 ABK74091.1 - 1.3e-13 51.3 0.6 2e-13 50.7 0.6 1.3 1 0 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 ABK74091.1 - 2.6e-05 24.0 0.8 0.00011 22.0 0.8 2.1 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 ABK74091.1 - 3.1e-05 24.3 0.7 8.4e-05 22.8 0.7 1.9 1 1 0 1 1 1 1 PDZ domain Peptidase_S46 PF10459.9 ABK74091.1 - 0.00078 18.2 2.8 0.082 11.5 1.2 2.1 2 0 0 2 2 2 2 Peptidase S46 HTH_18 PF12833.7 ABK74092.1 - 7.6e-19 67.8 0.8 1.8e-18 66.6 0.8 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 ABK74092.1 - 1.3e-11 44.3 0.0 7.4e-06 25.9 0.1 2.5 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding PF02311.19 ABK74092.1 - 3.7e-05 23.7 0.0 7.3e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_2 PF07883.11 ABK74092.1 - 0.00057 19.5 0.2 0.001 18.7 0.2 1.3 1 0 0 1 1 1 1 Cupin domain HTH_23 PF13384.6 ABK74092.1 - 0.0013 18.5 1.9 2.1 8.2 0.0 3.2 4 0 0 4 4 4 2 Homeodomain-like domain Exonuc_VII_L PF02601.15 ABK74093.1 - 7.2e-68 229.4 0.0 4.3e-60 203.9 0.4 2.0 1 1 1 2 2 2 2 Exonuclease VII, large subunit tRNA_anti_2 PF13742.6 ABK74093.1 - 1.1e-14 54.4 0.0 1.8e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti-codon PF01336.25 ABK74093.1 - 4.2e-05 23.4 0.1 9.7e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Peptidase_S66 PF02016.15 ABK74093.1 - 0.051 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 LD-carboxypeptidase N-terminal domain RbpA PF13397.6 ABK74095.1 - 4.4e-39 133.3 0.0 5e-39 133.1 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase-binding protein ABC_tran PF00005.27 ABK74096.1 - 1.6e-41 142.0 0.0 7.7e-20 71.8 0.0 3.3 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 ABK74096.1 - 6.2e-17 62.4 7.6 0.0029 17.5 0.4 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK74096.1 - 2.7e-11 43.4 0.9 0.015 14.8 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ABK74096.1 - 2.4e-07 31.5 4.6 0.0035 17.9 0.1 3.1 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.6 ABK74096.1 - 2.9e-06 27.4 0.1 0.047 13.9 0.0 3.0 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 ABK74096.1 - 6.6e-06 25.8 3.6 0.004 16.9 0.0 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ABK74096.1 - 9.3e-06 25.6 0.0 0.08 12.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 ABK74096.1 - 9.9e-05 22.8 13.4 0.0012 19.3 0.1 3.2 2 1 1 3 3 2 2 AAA ATPase domain Zeta_toxin PF06414.12 ABK74096.1 - 0.00061 19.1 4.1 0.067 12.5 0.0 2.6 3 0 0 3 3 2 2 Zeta toxin AAA_30 PF13604.6 ABK74096.1 - 0.00065 19.5 4.0 0.77 9.4 0.0 3.3 2 1 0 2 2 2 2 AAA domain ABC_tran_Xtn PF12848.7 ABK74096.1 - 0.00078 19.4 8.0 0.00078 19.4 8.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 ABK74096.1 - 0.0061 16.8 5.4 0.77 10.0 0.0 3.6 4 1 0 4 4 3 1 AAA domain NTPase_1 PF03266.15 ABK74096.1 - 0.0066 16.4 0.4 0.45 10.4 0.0 2.6 2 0 0 2 2 2 1 NTPase MMR_HSR1 PF01926.23 ABK74096.1 - 0.0077 16.3 0.1 2.4 8.3 0.0 3.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase NACHT PF05729.12 ABK74096.1 - 0.0095 15.9 0.0 0.27 11.2 0.0 2.3 2 0 0 2 2 2 1 NACHT domain Borrelia_P83 PF05262.11 ABK74096.1 - 0.011 14.2 0.4 0.014 13.9 0.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein APS_kinase PF01583.20 ABK74096.1 - 0.012 15.5 1.7 0.24 11.3 0.0 2.5 3 0 0 3 3 2 0 Adenylylsulphate kinase cobW PF02492.19 ABK74096.1 - 0.029 14.0 0.5 3 7.4 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 ABK74096.1 - 0.05 14.0 0.1 9.9 6.6 0.1 3.0 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 ABK74096.1 - 0.056 13.2 0.1 4.8 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 ABK74096.1 - 0.06 13.0 0.2 3.3 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain KAP_NTPase PF07693.14 ABK74096.1 - 0.082 12.1 0.0 3.7 6.7 0.0 2.2 2 1 0 2 2 2 0 KAP family P-loop domain AAA_33 PF13671.6 ABK74096.1 - 0.52 10.5 4.6 24 5.1 0.0 3.8 2 1 1 3 3 3 0 AAA domain AAA_13 PF13166.6 ABK74096.1 - 0.54 8.8 7.4 3.2 6.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 ABK74096.1 - 0.64 9.6 8.0 25 4.4 0.0 3.7 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 ABK74096.1 - 0.7 10.1 0.1 0.7 10.1 0.1 4.0 3 1 0 3 3 2 0 AAA domain DUF87 PF01935.17 ABK74096.1 - 0.83 9.7 2.7 16 5.5 0.0 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_18 PF13238.6 ABK74096.1 - 1.6 9.3 5.9 5 7.7 0.0 3.3 3 1 0 3 3 3 0 AAA domain MeaB PF03308.16 ABK74096.1 - 1.9 7.4 5.5 1.2 8.0 0.1 2.4 3 0 0 3 3 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_27 PF13514.6 ABK74096.1 - 2.2 7.8 11.6 2.8 7.5 0.0 3.9 3 1 1 4 4 4 0 AAA domain tRNA-synt_2 PF00152.20 ABK74097.1 - 5.8e-103 344.3 0.0 6.9e-103 344.0 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ABK74097.1 - 3.1e-16 59.1 0.1 5.6e-16 58.3 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain GAD PF02938.14 ABK74097.1 - 1.1e-13 51.3 0.0 2.9e-13 49.9 0.0 1.7 2 0 0 2 2 2 1 GAD domain tRNA-synt_2b PF00587.25 ABK74097.1 - 0.023 14.7 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 ABK74097.1 - 0.13 11.7 0.2 1.7 8.0 0.0 2.3 2 1 0 2 2 2 0 tRNA synthetases class II core domain (F) Sugar_tr PF00083.24 ABK74098.1 - 6.8e-40 137.3 24.6 7.6e-28 97.6 8.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ABK74098.1 - 1.1e-32 113.4 54.8 2.6e-22 79.2 27.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ABK74098.1 - 2.1e-06 26.6 19.7 6.9e-05 21.6 20.8 2.1 1 1 0 1 1 1 1 MFS/sugar transport protein OATP PF03137.20 ABK74098.1 - 0.00045 18.6 2.7 0.028 12.7 0.2 2.4 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family DUF4538 PF15061.6 ABK74098.1 - 3.7 7.4 4.9 17 5.2 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4538) DUF2510 PF10708.9 ABK74099.1 - 5.4e-11 42.1 6.9 5.4e-11 42.1 6.9 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2510) Carboxyl_trans PF01039.22 ABK74100.1 - 1.8e-199 663.5 0.1 2e-199 663.3 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 ABK74100.1 - 0.0011 18.5 1.9 0.0015 18.1 0.1 2.0 2 1 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) ATP-grasp_5 PF13549.6 ABK74101.1 - 6.9e-50 169.5 2.1 1.2e-49 168.7 2.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 ABK74101.1 - 1e-32 112.8 0.2 4.6e-31 107.5 0.1 3.0 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 ABK74101.1 - 7.1e-19 68.4 0.2 6.1e-17 62.2 0.0 3.3 3 0 0 3 3 3 1 CoA binding domain CoA_binding PF02629.19 ABK74101.1 - 0.00017 22.2 0.0 0.00078 20.1 0.0 2.2 1 0 0 1 1 1 1 CoA binding domain CPSase_L_D2 PF02786.17 ABK74101.1 - 0.001 18.6 0.1 0.0027 17.2 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_2 PF08442.10 ABK74101.1 - 0.038 13.6 0.0 0.082 12.5 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain DUF4344 PF14247.6 ABK74102.1 - 5e-74 248.7 0.1 5.9e-74 248.4 0.1 1.0 1 0 0 1 1 1 1 Putative metallopeptidase PolyA_pol_RNAbd PF12627.7 ABK74102.1 - 0.13 12.0 0.0 23 4.8 0.0 2.6 2 0 0 2 2 2 0 Probable RNA and SrmB- binding site of polymerase A peroxidase PF00141.23 ABK74103.1 - 2.7e-89 298.8 0.0 2e-47 161.8 0.0 2.2 2 0 0 2 2 2 2 Peroxidase DUF3130 PF11328.8 ABK74104.1 - 0.02 15.2 0.3 0.3 11.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3130 Aminotran_3 PF00202.21 ABK74105.1 - 3.2e-121 404.8 0.1 3.9e-121 404.5 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 ABK74105.1 - 0.0077 15.4 0.0 0.058 12.6 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II DUF503 PF04456.12 ABK74106.1 - 3.6e-29 100.5 0.3 4e-29 100.3 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF503) Fer4_15 PF13459.6 ABK74107.1 - 1.9e-11 44.6 0.5 3.1e-11 43.8 0.5 1.4 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_13 PF13370.6 ABK74107.1 - 2.6e-10 40.7 0.0 3.3e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_19 PF06902.11 ABK74107.1 - 0.0001 22.3 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 Divergent 4Fe-4S mono-cluster Fer4_6 PF12837.7 ABK74107.1 - 0.13 12.3 1.0 12 6.2 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain TetR_C_6 PF13977.6 ABK74108.1 - 3.4e-12 46.6 4.2 3.4e-12 46.6 4.2 1.9 2 0 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal TetR_N PF00440.23 ABK74108.1 - 9.8e-08 31.7 0.4 1.8e-07 30.8 0.4 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_31 PF17940.1 ABK74108.1 - 1.9e-06 28.0 7.1 1.9e-06 28.0 7.1 1.8 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain FHA PF00498.26 ABK74109.1 - 2.4e-33 114.3 2.9 8.2e-16 58.1 0.3 2.6 2 0 0 2 2 2 2 FHA domain ABC_tran PF00005.27 ABK74109.1 - 8.9e-32 110.5 0.0 1.3e-31 109.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter Yop-YscD_cpl PF16697.5 ABK74109.1 - 4.2e-28 97.5 0.0 2.7e-13 50.0 0.0 2.5 2 0 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain ABC2_membrane PF01061.24 ABK74109.1 - 2.4e-18 66.4 9.4 3.9e-18 65.6 9.4 1.3 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 ABK74109.1 - 1.7e-10 41.2 0.4 5.3e-08 33.0 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 ABK74109.1 - 1e-08 34.7 4.1 1.7e-08 34.0 4.1 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein SMC_N PF02463.19 ABK74109.1 - 1.9e-05 24.2 0.1 0.0082 15.6 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ABK74109.1 - 0.00041 20.6 0.2 0.0012 19.1 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ABK74109.1 - 0.011 15.9 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ABK74109.1 - 0.012 16.0 0.0 0.03 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 ABK74109.1 - 0.02 14.6 0.0 0.054 13.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 ABK74109.1 - 0.035 14.3 0.0 0.48 10.7 0.0 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 ABK74109.1 - 0.041 13.8 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 ABK74109.1 - 0.058 13.0 1.3 0.2 11.2 1.3 1.9 1 1 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 ABK74109.1 - 0.079 12.7 0.2 0.64 9.7 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase AAA PF00004.29 ABK74109.1 - 0.1 13.1 0.2 0.32 11.4 0.2 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 ABK74109.1 - 0.14 11.8 0.0 9.8 5.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 ABK74109.1 - 0.21 11.3 0.1 0.41 10.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain ABC2_membrane_2 PF12679.7 ABK74109.1 - 2.1 7.5 8.8 5.3 6.2 8.8 1.6 1 0 0 1 1 1 0 ABC-2 family transporter protein NTP_transf_3 PF12804.7 ABK74110.1 - 3e-23 82.9 8.0 3.8e-23 82.6 8.0 1.0 1 0 0 1 1 1 1 MobA-like NTP transferase domain Acyl_transf_1 PF00698.21 ABK74111.1 - 3.2e-19 69.6 5.3 4.1e-19 69.2 5.3 1.0 1 0 0 1 1 1 1 Acyl transferase domain SAT PF16073.5 ABK74111.1 - 0.92 9.2 10.2 0.055 13.2 1.2 2.2 2 0 0 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl-CoA_dh_M PF02770.19 ABK74112.1 - 6.7e-22 77.5 0.0 1.3e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 ABK74112.1 - 4.6e-18 65.9 0.0 7.5e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK74112.1 - 4.3e-17 62.8 0.0 8.2e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 ABK74112.1 - 0.0056 16.4 0.0 0.017 14.8 0.0 1.7 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Acyl-CoA_dh_2 PF08028.11 ABK74112.1 - 0.008 16.5 0.6 0.015 15.6 0.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain 4HBT PF03061.22 ABK74113.1 - 2.8e-08 34.0 0.1 4.4e-08 33.4 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Herpes_UL36 PF03586.13 ABK74113.1 - 0.083 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein CoA_transf_3 PF02515.17 ABK74114.1 - 2.6e-76 257.2 0.0 3.5e-76 256.7 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III YukD PF08817.10 ABK74115.1 - 4.3e-21 75.4 3.9 4.9e-21 75.2 1.3 2.4 2 0 0 2 2 2 1 WXG100 protein secretion system (Wss), protein YukD SAVED PF18145.1 ABK74115.1 - 0.46 10.3 1.7 8.6 6.1 0.1 2.3 2 0 0 2 2 2 0 SMODS-associated and fused to various effectors sensor domain IclR PF01614.18 ABK74116.1 - 5.7e-26 90.9 0.0 9e-26 90.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 ABK74116.1 - 3.4e-14 52.4 1.1 1.3e-13 50.5 0.4 2.2 2 0 0 2 2 2 1 IclR helix-turn-helix domain MarR_2 PF12802.7 ABK74116.1 - 2.7e-06 27.2 0.2 6.6e-06 25.9 0.2 1.6 1 0 0 1 1 1 1 MarR family Rubi_NSP_C PF12601.8 ABK74116.1 - 0.021 14.9 0.3 0.068 13.3 0.3 1.8 1 0 0 1 1 1 0 Rubivirus non-structural protein HTH_24 PF13412.6 ABK74116.1 - 0.023 14.3 0.0 0.06 12.9 0.0 1.7 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding TrmB PF01978.19 ABK74116.1 - 0.066 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_27 PF13463.6 ABK74116.1 - 0.07 13.6 0.0 0.2 12.2 0.0 1.7 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_9 PF08221.11 ABK74116.1 - 0.077 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain DUF2740 PF10872.8 ABK74116.1 - 0.14 12.1 0.0 4.4 7.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2740) SMC_Nse1 PF07574.13 ABK74116.1 - 0.15 11.9 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex DUF5632 PF18646.1 ABK74117.1 - 0.00069 19.6 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5632) PNTB_4TM PF12769.7 ABK74118.1 - 1.7e-32 111.7 6.0 2e-32 111.5 6.0 1.0 1 0 0 1 1 1 1 4TM region of pyridine nucleotide transhydrogenase, mitoch TrbC PF04956.13 ABK74118.1 - 0.0081 16.4 3.1 0.0081 16.4 3.1 1.5 1 1 0 1 1 1 1 TrbC/VIRB2 family COX14 PF14880.6 ABK74118.1 - 0.03 14.2 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 Cytochrome oxidase c assembly MR_MLE_C PF13378.6 ABK74119.1 - 2.4e-60 203.8 0.7 3.5e-60 203.3 0.7 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 ABK74119.1 - 5.3e-15 55.6 0.1 9.9e-15 54.8 0.1 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain PRiA4_ORF3 PF07929.11 ABK74120.1 - 1.4e-51 174.6 0.0 1.7e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein Bac_luciferase PF00296.20 ABK74121.1 - 2.2e-12 47.1 4.7 3.6e-08 33.2 0.0 2.3 1 1 1 2 2 2 2 Luciferase-like monooxygenase DNA_ligase_A_M PF01068.21 ABK74122.1 - 2.6e-43 148.1 0.0 3.5e-43 147.6 0.0 1.2 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 ABK74122.1 - 1.4e-11 45.1 0.0 1.5e-08 35.2 0.0 3.1 1 1 2 3 3 3 3 DNA ligase N terminus DNA_ligase_A_C PF04679.15 ABK74122.1 - 1.9e-11 44.4 0.0 8.8e-11 42.3 0.0 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region GntR PF00392.21 ABK74123.1 - 8.9e-18 63.7 0.5 1.8e-17 62.7 0.5 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family FCD PF07729.12 ABK74123.1 - 5.4e-17 62.4 8.6 1.2e-16 61.2 8.6 1.6 1 0 0 1 1 1 1 FCD domain HTH_41 PF14502.6 ABK74123.1 - 9.1e-05 22.1 0.1 0.0002 21.0 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain RP-C PF03428.13 ABK74123.1 - 0.0039 16.8 0.5 0.0071 16.0 0.5 1.6 1 1 0 1 1 1 1 Replication protein C N-terminal domain PaaX PF07848.12 ABK74123.1 - 0.0046 17.2 0.2 0.013 15.7 0.2 1.7 1 0 0 1 1 1 1 PaaX-like protein MarR_2 PF12802.7 ABK74123.1 - 0.0089 15.9 5.1 0.0089 15.9 0.3 3.1 3 0 0 3 3 3 1 MarR family Rrf2 PF02082.20 ABK74123.1 - 0.0097 16.2 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator TrmB PF01978.19 ABK74123.1 - 0.018 14.9 0.0 0.046 13.6 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 ABK74123.1 - 0.026 14.5 0.1 0.081 12.9 0.1 1.9 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain RsdA_SigD_bd PF16751.5 ABK74123.1 - 0.033 14.4 1.9 0.99 9.7 1.4 2.5 2 0 0 2 2 2 0 Anti-sigma-D factor RsdA to sigma factor binding region G_glu_transpept PF01019.21 ABK74123.1 - 0.04 12.7 0.0 0.92 8.2 0.0 2.0 2 0 0 2 2 2 0 Gamma-glutamyltranspeptidase PASTA PF03793.19 ABK74123.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 PASTA domain MarR PF01047.22 ABK74123.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 MarR family PRAI PF00697.22 ABK74124.1 - 0.18 11.6 0.1 2.6 7.8 0.1 2.0 2 0 0 2 2 2 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase CoA_transf_3 PF02515.17 ABK74125.1 - 2e-113 379.3 0.1 2.2e-113 379.1 0.1 1.0 1 0 0 1 1 1 1 CoA-transferase family III DeoC PF01791.9 ABK74125.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 DeoC/LacD family aldolase NIR_SIR PF01077.22 ABK74127.1 - 4.4e-51 172.5 0.0 2e-38 131.4 0.0 2.2 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 ABK74127.1 - 7.1e-28 96.3 0.4 1.6e-12 47.1 0.0 3.1 3 0 0 3 3 3 2 Nitrite/Sulfite reductase ferredoxin-like half domain BPD_transp_1 PF00528.22 ABK74128.1 - 2.3e-17 63.3 21.0 2.3e-17 63.3 21.0 1.9 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component CN_hydrolase PF00795.22 ABK74129.1 - 4.5e-38 131.1 0.0 5.9e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase AMP-binding PF00501.28 ABK74130.1 - 3.9e-79 266.2 0.0 5.5e-79 265.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK74130.1 - 6.3e-08 33.5 0.3 6.3e-08 33.5 0.3 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 ABK74130.1 - 0.22 10.3 0.0 1.4 7.7 0.0 2.0 2 0 0 2 2 2 0 GH3 auxin-responsive promoter RuvA_C PF07499.13 ABK74130.1 - 6.8 7.2 6.6 13 6.4 0.4 2.9 3 0 0 3 3 3 0 RuvA, C-terminal domain PEP_mutase PF13714.6 ABK74131.1 - 3.2e-59 200.3 3.8 3.7e-59 200.1 3.8 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Pantoate_transf PF02548.15 ABK74131.1 - 4.1e-06 26.4 0.0 3.1e-05 23.5 0.0 2.2 2 1 0 2 2 2 1 Ketopantoate hydroxymethyltransferase ICL PF00463.21 ABK74131.1 - 0.099 11.1 0.1 0.13 10.7 0.1 1.2 1 0 0 1 1 1 0 Isocitrate lyase family ComA PF02679.15 ABK74131.1 - 0.18 11.2 0.0 0.92 8.9 0.0 2.0 1 1 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) Acyl-CoA_dh_M PF02770.19 ABK74132.1 - 3.7e-25 87.9 0.0 7e-25 87.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 ABK74132.1 - 1.3e-15 57.9 0.8 2.6e-15 56.9 0.8 1.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK74132.1 - 5.9e-15 55.9 0.0 2.1e-14 54.2 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 ABK74132.1 - 0.043 13.5 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal MFS_1 PF07690.16 ABK74133.1 - 4e-33 114.8 74.1 2.6e-26 92.4 54.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ABK74133.1 - 0.00039 19.1 12.0 0.00039 19.1 12.0 2.7 1 1 1 2 2 2 1 MFS/sugar transport protein TetR_N PF00440.23 ABK74135.1 - 5.1e-08 32.6 0.0 2.6e-07 30.3 0.0 2.2 3 0 0 3 3 3 1 Bacterial regulatory proteins, tetR family RuvA_C PF07499.13 ABK74135.1 - 0.03 14.8 0.1 0.072 13.5 0.1 1.6 1 0 0 1 1 1 0 RuvA, C-terminal domain GLTT PF01744.20 ABK74136.1 - 5.3e-11 42.0 47.1 0.00017 21.2 2.9 6.6 5 1 1 6 6 6 5 GLTT repeat (6 copies) RGCC PF15151.6 ABK74136.1 - 2.3 8.4 5.4 1.2 9.4 0.4 2.7 1 1 1 3 3 3 0 Response gene to complement 32 protein family NAD_binding_2 PF03446.15 ABK74137.1 - 1.3e-33 116.4 0.0 2.2e-32 112.4 0.0 2.2 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 6PGD PF00393.19 ABK74137.1 - 4.9e-22 78.6 0.0 1.1e-21 77.5 0.0 1.6 1 1 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain 2-Hacid_dh_C PF02826.19 ABK74137.1 - 1e-05 25.0 0.0 1.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 ABK74137.1 - 0.001 19.6 0.0 0.0025 18.4 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.6 ABK74137.1 - 0.0075 16.5 0.0 0.016 15.5 0.0 1.6 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DDE_Tnp_ISL3 PF01610.17 ABK74138.1 - 1.6e-64 217.9 0.0 2.1e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Transposase zf-ISL3 PF14690.6 ABK74138.1 - 1.1e-09 38.8 4.6 1.8e-09 38.1 2.5 2.5 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HTH_Tnp_ISL3 PF13542.6 ABK74138.1 - 2.4e-08 33.2 1.6 7e-08 31.8 1.6 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 PqqD PF05402.12 ABK74139.1 - 5.8e-13 48.9 0.1 7.9e-13 48.5 0.1 1.1 1 0 0 1 1 1 1 Coenzyme PQQ synthesis protein D (PqqD) Lant_dehydr_N PF04738.13 ABK74139.1 - 0.0058 14.8 0.0 0.0061 14.7 0.0 1.1 1 0 0 1 1 1 1 Lantibiotic dehydratase, N terminus DUF742 PF05331.11 ABK74139.1 - 0.079 12.8 0.0 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF742) TylF PF05711.11 ABK74140.1 - 4e-104 347.5 0.0 4.7e-104 347.2 0.0 1.0 1 0 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) Methyltransf_24 PF13578.6 ABK74140.1 - 2.5e-11 44.5 0.0 4.1e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain STAS PF01740.21 ABK74140.1 - 0.13 11.9 0.0 4.5 6.9 0.0 2.3 2 0 0 2 2 2 0 STAS domain Peptidase_M18 PF02127.15 ABK74142.1 - 8.1e-138 459.8 0.0 9.6e-138 459.6 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 ABK74142.1 - 4.6e-05 22.6 0.0 0.053 12.5 0.0 2.2 1 1 1 2 2 2 2 M42 glutamyl aminopeptidase RibD_C PF01872.17 ABK74143.1 - 3.7e-16 59.5 0.1 1.2e-15 57.9 0.1 1.7 1 1 0 1 1 1 1 RibD C-terminal domain ABC_tran PF00005.27 ABK74144.1 - 2.9e-23 82.9 0.0 4.1e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK74144.1 - 3e-09 37.1 0.7 1.1e-07 32.0 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system MeaB PF03308.16 ABK74144.1 - 0.11 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF4162 PF13732.6 ABK74144.1 - 0.16 12.8 0.1 0.56 11.0 0.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4162) TetR_N PF00440.23 ABK74145.1 - 0.00011 22.0 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family RIX1 PF08167.12 ABK74145.1 - 0.014 15.1 0.0 0.09 12.5 0.0 1.9 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis ArAE_1_C PF11728.8 ABK74145.1 - 0.019 15.0 0.0 0.027 14.4 0.0 1.1 1 0 0 1 1 1 0 Putative aromatic acid exporter C-terminal domain HTH_AraC PF00165.23 ABK74145.1 - 0.13 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family DDE_3 PF13358.6 ABK74147.1 - 1.9e-24 86.1 0.0 2.9e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.6 ABK74147.1 - 3.9e-15 55.6 0.2 1.5e-14 53.8 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 ABK74147.1 - 1.2e-12 47.8 4.7 3.6e-11 43.0 0.2 2.8 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_23 PF13384.6 ABK74147.1 - 2.4e-11 43.1 1.9 1.2e-10 40.9 0.0 2.6 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 ABK74147.1 - 8.3e-10 39.1 0.1 3.6e-09 37.1 0.0 2.1 1 1 1 2 2 2 1 Homeodomain-like domain HTH_50 PF18024.1 ABK74147.1 - 6e-07 29.0 0.1 1.7e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 ABK74147.1 - 2.7e-06 27.8 0.1 6.2e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 leucine-zipper of insertion element IS481 HTH_Tnp_1 PF01527.20 ABK74147.1 - 0.028 14.7 0.1 0.096 13.0 0.0 1.9 2 0 0 2 2 2 0 Transposase HTH_1 PF00126.27 ABK74147.1 - 0.058 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_6 PF01418.17 ABK74147.1 - 0.079 12.9 0.0 2.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family rve_2 PF13333.6 ABK74147.1 - 0.1 12.8 0.0 1.3 9.2 0.0 2.2 2 0 0 2 2 2 0 Integrase core domain Erf4 PF10256.9 ABK74147.1 - 0.18 11.9 0.0 2.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family Peptidase_M20 PF01546.28 ABK74148.1 - 3.6e-21 75.8 0.4 5.4e-21 75.2 0.4 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 ABK74148.1 - 0.00042 20.1 0.0 0.0013 18.5 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M28 TetR_N PF00440.23 ABK74149.1 - 5.6e-19 67.7 0.1 5.9e-08 32.4 0.0 3.1 2 0 0 2 2 2 2 Bacterial regulatory proteins, tetR family TetR_C_13 PF16925.5 ABK74149.1 - 4.5e-09 36.2 0.1 0.0027 17.6 0.0 2.4 2 0 0 2 2 2 2 Tetracyclin repressor-like, C-terminal domain TetR_C_6 PF13977.6 ABK74149.1 - 0.018 15.3 17.7 0.039 14.2 1.4 3.8 4 0 0 4 4 4 0 BetI-type transcriptional repressor, C-terminal HTH_31 PF13560.6 ABK74149.1 - 0.96 9.8 12.7 7.7 7.0 1.0 3.5 3 1 0 3 3 3 0 Helix-turn-helix domain HxlR PF01638.17 ABK74150.1 - 1.7e-23 82.2 0.0 2.1e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_20 PF12840.7 ABK74150.1 - 0.0015 18.5 0.3 0.0026 17.8 0.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_27 PF13463.6 ABK74150.1 - 0.017 15.6 0.0 0.023 15.2 0.0 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain PadR PF03551.14 ABK74150.1 - 0.066 13.2 0.0 0.094 12.7 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family EamA PF00892.20 ABK74151.1 - 3.4e-14 53.2 29.9 9.2e-14 51.8 15.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family DoxX PF07681.12 ABK74152.1 - 1.3e-20 73.8 10.0 1.3e-20 73.8 10.0 2.0 3 0 0 3 3 3 1 DoxX DoxD PF04173.13 ABK74152.1 - 0.00016 21.6 1.3 0.00024 21.0 1.3 1.3 1 0 0 1 1 1 1 TQO small subunit DoxD MerR_1 PF13411.6 ABK74153.1 - 8e-19 67.5 0.0 1.1e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 ABK74153.1 - 4.8e-13 48.6 3.7 8.1e-13 47.9 3.7 1.4 1 0 0 1 1 1 1 MerR family regulatory protein MerR-DNA-bind PF09278.11 ABK74153.1 - 3.2e-05 24.4 0.1 5.7e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 MerR, DNA binding Ad_Cy_reg PF16701.5 ABK74153.1 - 0.006 16.3 0.6 0.0071 16.1 0.6 1.1 1 0 0 1 1 1 1 Adenylate cyclase regulatory domain HTH_17 PF12728.7 ABK74153.1 - 0.012 15.7 0.3 0.023 14.9 0.3 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DDE_Tnp_ISL3 PF01610.17 ABK74154.1 - 1.6e-64 217.9 0.0 2.1e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Transposase zf-ISL3 PF14690.6 ABK74154.1 - 1.1e-09 38.8 4.6 1.8e-09 38.1 2.5 2.5 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HTH_Tnp_ISL3 PF13542.6 ABK74154.1 - 2.4e-08 33.2 1.6 7e-08 31.8 1.6 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 Thiamine_BP PF01910.17 ABK74155.1 - 5.5e-30 103.1 0.1 6.1e-30 103.0 0.1 1.0 1 0 0 1 1 1 1 Thiamine-binding protein Ykof PF07615.11 ABK74155.1 - 0.018 15.5 0.0 0.025 15.1 0.0 1.2 1 0 0 1 1 1 0 YKOF-related Family adh_short_C2 PF13561.6 ABK74156.1 - 4.8e-60 203.0 0.1 6.5e-60 202.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK74156.1 - 4.5e-44 150.2 0.0 6e-44 149.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK74156.1 - 4e-18 66.0 0.2 5.3e-18 65.6 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK74156.1 - 0.00011 21.8 0.0 0.00052 19.6 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ABK74156.1 - 0.032 14.1 0.1 0.042 13.7 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding 3HCDH_N PF02737.18 ABK74156.1 - 0.11 12.4 0.4 0.17 11.8 0.4 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain OKR_DC_1 PF01276.20 ABK74156.1 - 0.24 10.1 0.0 0.34 9.6 0.0 1.1 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain MaoC_dehydrat_N PF13452.6 ABK74157.1 - 4.2e-07 30.2 0.0 4.9e-06 26.7 0.0 2.5 2 1 0 2 2 2 1 N-terminal half of MaoC dehydratase MaoC_dehydratas PF01575.19 ABK74157.1 - 2.8e-06 26.9 0.2 4.5e-06 26.2 0.2 1.3 1 0 0 1 1 1 1 MaoC like domain PKS_DE PF18369.1 ABK74157.1 - 0.096 13.3 1.0 0.24 12.0 1.0 1.6 1 0 0 1 1 1 0 Polyketide synthase dimerisation element domain WXG100 PF06013.12 ABK74158.1 - 1.5e-12 47.6 0.0 2e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Proteins of 100 residues with WXG Beta-lactamase PF00144.24 ABK74159.1 - 2.9e-67 227.3 2.7 3.7e-67 226.9 2.7 1.0 1 0 0 1 1 1 1 Beta-lactamase DUF3499 PF12005.8 ABK74160.1 - 3.1e-48 163.5 0.0 3.9e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3499) DUF952 PF06108.12 ABK74161.1 - 4.1e-29 100.4 0.0 4.7e-29 100.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) SIP PF04954.13 ABK74162.1 - 1.1e-21 77.6 0.2 2.1e-21 76.7 0.2 1.5 1 0 0 1 1 1 1 Siderophore-interacting protein FAD_binding_9 PF08021.11 ABK74162.1 - 2.4e-14 53.6 0.0 5.7e-14 52.4 0.0 1.6 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain MaoC_dehydratas PF01575.19 ABK74163.1 - 7.7e-29 99.8 0.0 9.9e-29 99.4 0.0 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 ABK74163.1 - 6.6e-05 23.1 0.0 9e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase MFS_1 PF07690.16 ABK74165.1 - 7.6e-46 156.6 46.5 7.6e-46 156.6 46.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 ABK74165.1 - 0.14 10.5 37.2 0.014 13.8 16.0 2.5 1 1 0 2 2 2 0 Transmembrane secretion effector Aminotran_5 PF00266.19 ABK74166.1 - 3.4e-136 454.1 0.0 3.9e-136 453.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 ABK74166.1 - 0.0066 15.0 0.0 0.01 14.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 ABK74166.1 - 0.0097 15.1 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II SelA PF03841.13 ABK74166.1 - 0.15 11.0 0.0 0.31 10.0 0.0 1.4 1 1 0 1 1 1 0 L-seryl-tRNA selenium transferase F420H2_quin_red PF04075.14 ABK74167.1 - 1.3e-37 128.9 0.0 1.6e-37 128.5 0.0 1.0 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase Putative_PNPOx PF01243.20 ABK74167.1 - 0.00065 19.8 0.0 0.001 19.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase NAD_Gly3P_dh_C PF07479.14 ABK74168.1 - 7.1e-50 169.0 4.3 1e-49 168.5 3.4 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 ABK74168.1 - 9.1e-49 165.4 0.0 2.9e-48 163.8 0.0 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 ABK74168.1 - 3.3e-07 30.8 0.0 4.6e-06 27.1 0.0 2.6 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.17 ABK74168.1 - 0.0017 17.4 0.0 0.0032 16.5 0.0 1.5 1 0 0 1 1 1 1 Prephenate dehydrogenase ApbA PF02558.16 ABK74168.1 - 0.0039 16.9 0.0 0.0064 16.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA HgmA PF04209.13 ABK74169.1 - 5e-08 32.1 0.2 7.6e-08 31.5 0.2 1.2 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Cupin_2 PF07883.11 ABK74169.1 - 0.074 12.8 0.3 0.48 10.2 0.0 2.4 3 0 0 3 3 3 0 Cupin domain Glycos_transf_1 PF00534.20 ABK74170.1 - 1.9e-41 141.5 0.0 2.9e-41 140.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ABK74170.1 - 3.3e-29 102.0 0.1 6.4e-29 101.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ABK74170.1 - 1.6e-17 64.0 3.0 6.3e-17 62.1 0.8 2.6 3 0 0 3 3 3 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 ABK74170.1 - 2.1e-11 44.1 0.0 4.4e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 ABK74170.1 - 0.011 15.8 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like PRiA4_ORF3 PF07929.11 ABK74171.1 - 2.1e-51 174.1 0.0 2.5e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein Mycobact_memb PF05423.13 ABK74172.1 - 5.7e-34 117.0 0.0 6.7e-34 116.8 0.0 1.1 1 0 0 1 1 1 1 Mycobacterium membrane protein ChiW_Ig_like PF18683.1 ABK74172.1 - 0.062 13.5 0.0 0.086 13.1 0.0 1.2 1 0 0 1 1 1 0 Chitinase W immunoglobulin-like domain DUF1206 PF06724.11 ABK74173.1 - 3.3e-48 161.6 54.2 2.4e-19 69.2 17.6 3.2 3 0 0 3 3 3 3 Domain of Unknown Function (DUF1206) DctQ PF04290.12 ABK74173.1 - 6.4 6.7 11.6 0.096 12.6 1.0 2.8 3 0 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component E1-E2_ATPase PF00122.20 ABK74175.1 - 2.5e-50 170.5 1.2 2.5e-50 170.5 1.2 3.0 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ABK74175.1 - 1e-43 149.2 3.4 1e-43 149.2 3.4 2.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ABK74175.1 - 6.4e-23 82.2 7.8 1.7e-19 70.9 0.3 3.6 4 0 0 4 4 4 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ABK74175.1 - 7.9e-21 73.9 0.0 1.4e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ABK74175.1 - 7.7e-17 60.7 0.0 1.7e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.7 ABK74175.1 - 7.3e-07 29.8 0.6 4.2e-06 27.3 0.1 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ABK74175.1 - 7e-06 26.0 2.0 4.7e-05 23.2 0.7 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase FixS PF03597.15 ABK74175.1 - 0.048 13.4 1.3 0.18 11.6 1.3 2.0 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type ADH_zinc_N PF00107.26 ABK74176.1 - 1.6e-12 47.6 0.1 2.6e-12 46.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ABK74176.1 - 2.8e-12 47.9 0.0 5.3e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ABK74176.1 - 4.9e-08 32.8 0.0 3e-06 27.1 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain YAcAr PF10686.9 ABK74176.1 - 0.062 13.3 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family 2-Hacid_dh_C PF02826.19 ABK74176.1 - 0.12 11.8 0.5 0.29 10.5 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TetR_N PF00440.23 ABK74177.1 - 4.9e-11 42.2 0.0 8.4e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 ABK74177.1 - 6.8e-07 29.6 0.3 6.8e-07 29.6 0.3 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_13 PF16925.5 ABK74177.1 - 2.8e-05 24.0 0.1 7.9e-05 22.6 0.0 1.7 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_6 PF13977.6 ABK74177.1 - 6.8e-05 23.1 4.1 0.0001 22.5 2.5 2.1 1 1 1 2 2 2 1 BetI-type transcriptional repressor, C-terminal HEPN_RnaseLS PF18869.1 ABK74177.1 - 0.051 13.7 0.1 0.14 12.3 0.0 1.7 2 0 0 2 2 2 0 RnaseLS-like HEPN DUF2505 PF10698.9 ABK74178.1 - 3.1e-47 160.6 0.1 3.4e-47 160.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2505) Rhomboid PF01694.22 ABK74179.1 - 3.1e-24 85.7 17.4 4.1e-24 85.3 17.4 1.2 1 0 0 1 1 1 1 Rhomboid family C_GCAxxG_C_C PF09719.10 ABK74179.1 - 0.0099 16.2 0.0 0.015 15.5 0.0 1.2 1 0 0 1 1 1 1 Putative redox-active protein (C_GCAxxG_C_C) DUF732 PF05305.14 ABK74180.1 - 1.1e-15 57.7 3.5 1.4e-15 57.4 3.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF732) TauE PF01925.19 ABK74181.1 - 0.0034 17.1 9.2 0.0044 16.7 9.2 1.1 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Phage_holin_3_6 PF07332.11 ABK74181.1 - 0.035 14.1 13.3 0.026 14.6 2.8 2.1 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Flexi_CP PF00286.20 ABK74181.1 - 0.13 12.2 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Viral coat protein DUF4131 PF13567.6 ABK74181.1 - 0.93 9.1 7.0 2.2 7.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Methyltransf_14 PF08484.11 ABK74184.1 - 4.7e-25 88.2 0.0 1.1e-24 87.0 0.0 1.6 2 0 0 2 2 2 1 C-methyltransferase C-terminal domain Methyltransf_13 PF08421.11 ABK74184.1 - 1.2e-11 44.7 0.1 2e-11 43.9 0.1 1.3 1 0 0 1 1 1 1 Putative zinc binding domain Methyltransf_23 PF13489.6 ABK74184.1 - 1.2e-05 25.2 0.1 0.00054 19.8 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABK74184.1 - 0.014 16.0 0.0 0.033 14.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PapA_C PF16911.5 ABK74184.1 - 0.041 13.9 0.1 0.072 13.2 0.1 1.4 1 0 0 1 1 1 0 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus Ribosomal_L12_N PF16320.5 ABK74184.1 - 2.5 7.9 0.0 2.5 7.9 0.0 2.9 3 0 0 3 3 3 0 Ribosomal protein L7/L12 dimerisation domain MttA_Hcf106 PF02416.16 ABK74185.1 - 0.014 14.7 0.1 0.016 14.6 0.1 1.3 1 1 0 1 1 1 0 mttA/Hcf106 family tRNA-synt_1c PF00749.21 ABK74186.1 - 1e-77 261.2 0.0 1.2e-77 260.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain DUF4258 PF14076.6 ABK74186.1 - 0.086 13.2 0.0 0.44 10.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4258) EHN PF06441.12 ABK74187.1 - 3.1e-34 117.6 0.6 2e-33 115.0 0.1 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 ABK74187.1 - 6.8e-18 65.2 0.1 1.6e-17 64.0 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK74187.1 - 8.4e-08 33.1 7.4 8.4e-08 33.1 7.4 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Lon_C PF05362.13 ABK74188.1 - 2e-10 40.5 0.2 3.5e-10 39.8 0.2 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain PDZ_2 PF13180.6 ABK74188.1 - 5.3e-10 39.5 0.1 1.2e-09 38.3 0.1 1.7 1 1 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 ABK74188.1 - 1.1e-06 28.4 0.0 2.4e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 ABK74188.1 - 0.0011 19.2 0.0 0.0026 18.0 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_1 PF12812.7 ABK74188.1 - 0.0052 16.8 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 PDZ-like domain Tricorn_PDZ PF14685.6 ABK74188.1 - 0.073 13.0 0.1 0.59 10.1 0.0 2.2 2 0 0 2 2 2 0 Tricorn protease PDZ domain ChlI PF13541.6 ABK74188.1 - 0.092 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Subunit ChlI of Mg-chelatase TetR_C_13 PF16925.5 ABK74189.1 - 1.8e-15 56.9 0.0 2.8e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK74189.1 - 9.6e-14 50.9 0.1 4.1e-13 48.9 0.0 2.2 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 ABK74189.1 - 2.4e-06 27.7 1.0 4.7e-06 26.8 1.0 1.4 1 0 0 1 1 1 1 BetI-type transcriptional repressor, C-terminal TetR_C_11 PF16859.5 ABK74189.1 - 3.5e-05 24.1 0.1 6.9e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain DUF647 PF04884.14 ABK74189.1 - 0.0099 15.5 0.3 0.017 14.8 0.3 1.4 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis TetR_C_25 PF17933.1 ABK74189.1 - 0.097 13.0 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TetR_C_29 PF17938.1 ABK74189.1 - 0.16 12.0 0.1 0.44 10.6 0.0 1.8 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Putative_PNPOx PF01243.20 ABK74190.1 - 1.7e-05 24.9 0.0 2.5e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 ABK74190.1 - 0.0001 22.3 0.1 0.00044 20.2 0.1 1.8 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase SPO11_like PF03533.14 ABK74190.1 - 0.032 14.3 0.0 0.032 14.3 0.0 1.9 2 0 0 2 2 2 0 SPO11 homologue Pyrid_ox_like PF16242.5 ABK74190.1 - 0.059 13.0 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like 2OG-FeII_Oxy_2 PF13532.6 ABK74191.1 - 1e-13 51.9 0.0 3.5e-13 50.2 0.0 1.7 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily Aminotran_3 PF00202.21 ABK74192.1 - 3.7e-114 381.5 0.0 4.4e-114 381.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 ABK74192.1 - 0.038 13.2 0.0 0.072 12.2 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II Acyl-CoA_dh_1 PF00441.24 ABK74193.1 - 1.9e-14 54.1 0.0 3.2e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK74193.1 - 3.5e-10 40.5 0.0 8.6e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ABK74193.1 - 4.3e-05 23.8 0.0 0.00013 22.2 0.0 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK74193.1 - 0.07 13.3 0.1 0.41 10.9 0.0 2.3 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, middle domain ABC_tran PF00005.27 ABK74194.1 - 8.2e-28 97.6 0.0 1.7e-27 96.6 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK74194.1 - 8.9e-06 25.7 0.0 0.0024 17.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ABK74194.1 - 0.00037 20.8 0.0 0.0007 19.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ABK74194.1 - 0.0021 18.4 0.7 0.0033 17.8 0.7 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 ABK74194.1 - 0.003 17.7 0.2 0.01 16.0 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ABK74194.1 - 0.0043 16.8 0.1 0.0062 16.3 0.1 1.4 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ABK74194.1 - 0.0044 17.0 0.0 0.0069 16.3 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase SbcCD_C PF13558.6 ABK74194.1 - 0.0084 16.3 0.5 0.085 13.1 0.5 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 ABK74194.1 - 0.029 14.1 0.1 0.064 13.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 ABK74194.1 - 0.036 14.0 0.5 0.14 12.0 0.2 2.1 1 1 1 2 2 2 0 NACHT domain AAA_25 PF13481.6 ABK74194.1 - 0.036 13.6 1.3 0.085 12.4 0.4 2.1 2 1 0 2 2 2 0 AAA domain NIR_SIR_ferr PF03460.17 ABK74194.1 - 0.045 13.6 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 Nitrite/Sulfite reductase ferredoxin-like half domain AAA_28 PF13521.6 ABK74194.1 - 0.045 14.0 1.4 0.15 12.3 1.4 2.1 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ABK74194.1 - 0.051 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase TsaE PF02367.17 ABK74194.1 - 0.095 12.7 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 ABK74194.1 - 0.1 13.1 0.1 0.21 12.1 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 ABK74194.1 - 0.14 12.6 0.1 0.27 11.7 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 ABK74194.1 - 0.15 11.2 0.2 0.34 10.1 0.2 1.6 1 1 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 ABK74194.1 - 0.16 12.5 0.3 0.37 11.3 0.3 1.7 1 1 0 1 1 1 0 AAA domain DLIC PF05783.11 ABK74194.1 - 0.19 10.5 0.1 0.28 10.0 0.1 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Abhydrolase_1 PF00561.20 ABK74195.1 - 5.5e-24 85.2 0.1 9.2e-22 77.9 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK74195.1 - 5e-22 79.6 5.1 6.3e-22 79.3 5.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK74195.1 - 1.3e-21 77.0 0.1 2e-16 60.0 0.1 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 ABK74195.1 - 3.9e-06 26.7 0.0 1.7e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_4 PF08386.10 ABK74195.1 - 0.00012 22.1 0.0 0.00075 19.6 0.0 2.1 2 0 0 2 2 2 1 TAP-like protein Peptidase_S9 PF00326.21 ABK74195.1 - 0.013 15.0 0.1 15 5.0 0.0 3.1 3 0 0 3 3 3 0 Prolyl oligopeptidase family Esterase PF00756.20 ABK74195.1 - 0.063 12.9 0.1 0.2 11.3 0.1 2.0 2 1 0 2 2 2 0 Putative esterase Ser_hydrolase PF06821.13 ABK74195.1 - 0.078 12.8 0.0 2.5 8.0 0.0 2.7 2 1 1 3 3 3 0 Serine hydrolase Thioesterase PF00975.20 ABK74195.1 - 0.1 12.7 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Acyl-CoA_dh_1 PF00441.24 ABK74196.1 - 1.8e-46 158.1 2.3 2.9e-46 157.4 2.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK74196.1 - 2.2e-32 112.1 0.1 4.5e-32 111.1 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ABK74196.1 - 1.6e-21 76.3 0.0 4.9e-21 74.7 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ABK74196.1 - 2.7e-19 69.8 1.5 4.5e-19 69.1 1.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 ABK74196.1 - 0.0094 16.5 0.0 0.017 15.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal UPF0029 PF01205.19 ABK74196.1 - 0.11 12.8 0.1 4 7.8 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein family UPF0029 Pyridoxal_deC PF00282.19 ABK74197.1 - 3.8e-46 157.5 0.0 4.6e-46 157.2 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 ABK74197.1 - 1.9e-07 30.7 0.4 2.7e-07 30.2 0.4 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 ABK74197.1 - 5.5e-06 25.6 0.0 9.8e-06 24.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V SepSecS PF05889.13 ABK74197.1 - 0.024 13.3 0.0 0.037 12.7 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS LytR_C PF13399.6 ABK74197.1 - 3.5 8.7 5.4 0.93 10.5 0.8 2.4 3 0 0 3 3 3 0 LytR cell envelope-related transcriptional attenuator TetR_N PF00440.23 ABK74198.1 - 1.4e-17 63.2 1.5 3e-17 62.2 1.5 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_IclR PF09339.10 ABK74198.1 - 0.003 17.3 3.7 0.0035 17.1 0.1 2.7 3 0 0 3 3 3 1 IclR helix-turn-helix domain LacI PF00356.21 ABK74198.1 - 0.036 13.9 0.0 0.11 12.3 0.0 1.9 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family HTH_38 PF13936.6 ABK74198.1 - 0.054 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain MarR_2 PF12802.7 ABK74198.1 - 0.088 12.7 1.4 0.42 10.5 0.1 2.6 2 1 0 2 2 2 0 MarR family TetR_C_1 PF02909.17 ABK74199.1 - 3.4e-18 65.8 0.1 1.1e-17 64.2 0.1 1.8 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK74199.1 - 0.003 17.3 0.0 0.009 15.8 0.0 1.9 1 1 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_20 PF12840.7 ABK74199.1 - 0.054 13.6 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Lactamase_B_2 PF12706.7 ABK74200.1 - 1.2e-12 47.8 0.1 6.5e-12 45.4 0.1 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RNase_J_C PF17770.1 ABK74200.1 - 2.7e-11 44.3 0.0 4.8e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease J C-terminal domain RMMBL PF07521.12 ABK74200.1 - 4.7e-10 39.3 0.0 1.7e-09 37.5 0.0 1.9 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 ABK74200.1 - 5e-09 36.4 5.1 2.3e-08 34.3 5.1 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily PriCT_1 PF08708.11 ABK74200.1 - 0.19 11.5 0.0 0.46 10.3 0.0 1.6 1 0 0 1 1 1 0 Primase C terminal 1 (PriCT-1) Transp_cyt_pur PF02133.15 ABK74201.1 - 9.7e-103 344.3 35.1 1.2e-102 344.0 35.1 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Lactamase_B_2 PF12706.7 ABK74202.1 - 2.9e-16 59.6 1.8 3.5e-16 59.3 1.8 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ABK74202.1 - 1.6e-11 44.4 0.1 3.2e-11 43.4 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ABK74202.1 - 0.0015 18.6 5.6 0.014 15.4 5.6 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily AAA_5 PF07728.14 ABK74204.1 - 1.1e-12 48.2 0.1 5.4e-12 45.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 ABK74204.1 - 9.6e-10 39.0 0.0 2.5e-09 37.6 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ABK74204.1 - 5.6e-08 33.4 0.6 1.2e-07 32.3 0.6 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_3 PF07726.11 ABK74204.1 - 1.9e-07 31.0 0.1 0.0016 18.3 0.1 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 ABK74204.1 - 3.6e-05 24.3 0.0 5.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 ABK74204.1 - 0.00017 21.3 0.0 0.46 10.2 0.0 2.2 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_6 PF12774.7 ABK74204.1 - 0.00036 19.6 0.0 0.00056 19.0 0.0 1.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_22 PF13401.6 ABK74204.1 - 0.0004 20.7 0.8 0.0066 16.7 0.8 2.3 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 ABK74204.1 - 0.00092 19.2 0.2 0.075 13.0 0.0 2.3 2 0 0 2 2 2 1 NACHT domain RuvB_N PF05496.12 ABK74204.1 - 0.0013 18.5 0.2 0.49 10.1 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 ABK74204.1 - 0.0046 17.1 0.0 0.009 16.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_30 PF13604.6 ABK74204.1 - 0.0063 16.3 0.4 0.021 14.6 0.4 1.9 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 ABK74204.1 - 0.012 15.4 0.1 0.058 13.1 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein TsaE PF02367.17 ABK74204.1 - 0.018 15.0 0.1 0.042 13.8 0.1 1.6 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 ABK74204.1 - 0.028 14.7 0.3 10 6.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 ABK74204.1 - 0.043 13.9 0.0 2.6 8.1 0.0 2.3 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 ABK74204.1 - 0.047 13.1 1.1 0.069 12.5 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 ABK74204.1 - 0.052 13.7 0.0 0.53 10.4 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_lid_2 PF17863.1 ABK74204.1 - 0.092 12.6 0.3 0.092 12.6 0.3 2.9 3 0 0 3 3 2 0 AAA lid domain AAA_28 PF13521.6 ABK74204.1 - 0.1 12.8 0.0 0.38 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 ABK74204.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ABK74204.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Porphobil_deam PF01379.20 ABK74205.1 - 2.9e-67 226.2 0.0 3.6e-67 225.8 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 ABK74205.1 - 1.4e-19 70.2 0.4 3.4e-19 69.0 0.4 1.7 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain GSDH PF07995.11 ABK74206.1 - 2.4e-73 247.3 0.0 3.5e-73 246.8 0.0 1.2 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase SGL PF08450.12 ABK74206.1 - 0.00014 21.5 0.1 3 7.4 0.0 4.3 3 2 2 5 5 5 1 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 ABK74206.1 - 0.00015 21.6 1.5 9.8 6.8 0.1 4.3 4 0 0 4 4 4 2 Two component regulator propeller NHL PF01436.21 ABK74206.1 - 0.0007 19.5 0.0 0.94 9.6 0.0 4.3 4 0 0 4 4 4 1 NHL repeat DUF5122 PF17164.4 ABK74206.1 - 0.057 13.7 0.4 0.54 10.6 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF5122) beta-propeller Putative_PNPOx PF01243.20 ABK74207.1 - 1.3e-13 50.9 0.0 1.9e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 ABK74207.1 - 0.007 16.0 0.0 0.01 15.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Pyrid_oxidase_2 PF13883.6 ABK74207.1 - 0.15 12.0 0.0 0.41 10.6 0.0 1.7 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Glycos_transf_2 PF00535.26 ABK74208.1 - 2.5e-12 47.0 0.0 4.1e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ABK74208.1 - 6.8e-09 35.9 0.0 1e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 ABK74208.1 - 0.0009 18.8 0.0 0.0013 18.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 NTP_transf_3 PF12804.7 ABK74208.1 - 0.0083 16.5 0.9 0.0094 16.3 0.1 1.5 2 0 0 2 2 2 1 MobA-like NTP transferase domain DUF5302 PF17227.2 ABK74209.1 - 4.6e-20 72.3 10.2 5e-20 72.2 10.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5302) WES_acyltransf PF03007.16 ABK74210.1 - 1.1e-57 195.9 0.3 2.1e-57 194.9 0.3 1.5 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 ABK74210.1 - 3.4e-27 95.2 0.0 4.9e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) Condensation PF00668.20 ABK74210.1 - 0.09 11.4 0.1 0.95 8.1 0.1 2.0 2 0 0 2 2 2 0 Condensation domain AATase PF07247.12 ABK74210.1 - 0.2 10.2 0.0 0.29 9.7 0.0 1.1 1 0 0 1 1 1 0 Alcohol acetyltransferase GDPD PF03009.17 ABK74211.1 - 1.6e-49 169.0 0.0 1.8e-49 168.8 0.0 1.0 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family FUR PF01475.19 ABK74212.1 - 2e-21 76.3 0.0 2.4e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Ferric uptake regulator family TrmB PF01978.19 ABK74212.1 - 0.00085 19.2 0.0 0.0017 18.2 0.0 1.5 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_27 PF13463.6 ABK74212.1 - 0.0012 19.3 0.0 0.0018 18.8 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain AbiEi_3 PF11459.8 ABK74212.1 - 0.0071 16.1 0.0 0.0089 15.7 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator, AbiEi antitoxin, Type IV TA system Nudix_N_2 PF14803.6 ABK74212.1 - 0.014 15.3 1.0 0.014 15.3 1.0 2.3 2 0 0 2 2 2 0 Nudix N-terminal Dimerisation2 PF16864.5 ABK74212.1 - 0.016 15.1 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 Dimerisation domain MarR_2 PF12802.7 ABK74212.1 - 0.058 13.3 1.4 0.14 12.0 0.5 2.2 2 1 0 2 2 2 0 MarR family FYVE PF01363.21 ABK74212.1 - 0.14 12.3 2.6 0.31 11.2 2.6 1.6 1 1 0 1 1 1 0 FYVE zinc finger MFS_1 PF07690.16 ABK74213.1 - 8.1e-43 146.7 47.4 8.1e-43 146.7 47.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.13 ABK74213.1 - 0.00032 19.2 10.1 0.00032 19.2 10.1 2.9 2 1 1 3 3 3 1 Transmembrane secretion effector DUF3087 PF11286.8 ABK74213.1 - 0.79 9.2 1.8 17 4.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) OATP PF03137.20 ABK74213.1 - 3.2 5.9 9.9 0.2 9.9 0.9 2.9 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family BPD_transp_1 PF00528.22 ABK74214.1 - 5.1e-16 58.9 18.2 5.1e-16 58.9 18.2 1.9 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Aldo_ket_red PF00248.21 ABK74216.1 - 2.4e-41 141.8 0.0 5.9e-40 137.3 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family FeoA PF04023.14 ABK74216.1 - 0.092 13.0 0.7 1.3 9.3 0.2 2.5 2 0 0 2 2 2 0 FeoA domain MlaE PF02405.16 ABK74217.1 - 2.5e-50 171.1 28.2 3.4e-50 170.7 28.2 1.1 1 0 0 1 1 1 1 Permease MlaE FMN_dh PF01070.18 ABK74218.1 - 1.3e-111 373.0 0.0 1.5e-111 372.8 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 ABK74218.1 - 7.1e-06 25.3 0.7 1.6e-05 24.1 0.5 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 ABK74218.1 - 5.9e-05 22.5 0.5 0.033 13.5 0.2 2.3 1 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 ABK74218.1 - 0.00027 20.2 0.1 0.00051 19.3 0.1 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 ABK74218.1 - 0.026 13.9 0.5 0.042 13.2 0.5 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase His_biosynth PF00977.21 ABK74218.1 - 0.03 13.8 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 Histidine biosynthesis protein Trp_syntA PF00290.20 ABK74218.1 - 0.1 11.5 0.0 7.2 5.4 0.0 2.7 3 0 0 3 3 3 0 Tryptophan synthase alpha chain Abhydrolase_3 PF07859.13 ABK74219.1 - 7e-42 143.7 0.9 9.2e-42 143.3 0.9 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ABK74219.1 - 6e-06 25.4 0.0 8.1e-06 24.9 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 ABK74219.1 - 9.8e-05 21.9 0.0 0.00023 20.7 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 ABK74219.1 - 0.015 14.6 0.0 0.047 12.9 0.0 1.7 1 1 1 2 2 2 0 Serine aminopeptidase, S33 YjeF_N PF03853.15 ABK74219.1 - 0.047 13.6 0.7 11 5.9 0.0 2.6 1 1 1 3 3 3 0 YjeF-related protein N-terminus Abhydrolase_1 PF00561.20 ABK74219.1 - 0.057 13.0 0.0 0.082 12.5 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 ABK74219.1 - 0.077 12.5 0.0 1.8 8.1 0.0 2.1 1 1 1 2 2 2 0 Dienelactone hydrolase family BPD_transp_1 PF00528.22 ABK74220.1 - 8.6e-13 48.4 14.0 1.4e-12 47.7 11.1 2.1 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component TraG_N PF07916.11 ABK74220.1 - 1.3 7.8 6.6 2.6 6.8 6.6 1.5 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Lpp-LpqN PF10738.9 ABK74222.1 - 1.3e-61 207.0 0.0 1.9e-61 206.6 0.0 1.2 1 0 0 1 1 1 1 Probable lipoprotein LpqN adh_short_C2 PF13561.6 ABK74223.1 - 1.6e-60 204.6 6.0 1.8e-60 204.4 6.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK74223.1 - 6.7e-47 159.5 4.3 8.2e-47 159.2 4.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK74223.1 - 5e-09 36.3 2.5 7.1e-09 35.8 2.5 1.2 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 ABK74223.1 - 0.0046 17.0 0.4 0.0098 16.0 0.4 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Peripla_BP_6 PF13458.6 ABK74223.1 - 0.011 15.5 3.9 0.015 15.0 3.9 1.2 1 0 0 1 1 1 0 Periplasmic binding protein 3HCDH_N PF02737.18 ABK74223.1 - 0.023 14.6 5.2 0.057 13.3 5.2 1.7 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 ABK74223.1 - 0.024 15.2 2.1 0.07 13.7 2.1 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_3 PF03447.16 ABK74223.1 - 0.032 14.9 3.1 0.21 12.2 0.6 2.5 1 1 1 2 2 2 0 Homoserine dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 ABK74223.1 - 0.036 13.4 0.3 0.069 12.5 0.3 1.5 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 ABK74223.1 - 0.047 13.1 1.5 0.087 12.3 1.5 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 ABK74223.1 - 0.052 13.8 0.4 0.091 13.0 0.4 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain HATPase_c_2 PF13581.6 ABK74223.1 - 0.13 12.3 0.2 0.21 11.6 0.2 1.3 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain BPD_transp_1 PF00528.22 ABK74224.1 - 2.3e-28 99.2 10.1 2.3e-28 99.2 10.1 1.8 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Methyltransf_25 PF13649.6 ABK74225.1 - 2e-14 54.1 0.0 3.1e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABK74225.1 - 3e-11 43.8 0.0 4.4e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK74225.1 - 3.7e-10 40.4 0.0 5.4e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABK74225.1 - 5.5e-08 32.7 0.0 8e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABK74225.1 - 7.1e-07 29.2 0.0 1.2e-06 28.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 ABK74225.1 - 7.3e-06 25.5 0.0 9.6e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB CheR PF01739.18 ABK74225.1 - 1e-05 25.1 0.0 0.00018 21.0 0.0 2.5 2 1 0 2 2 2 1 CheR methyltransferase, SAM binding domain MTS PF05175.14 ABK74225.1 - 0.0014 18.2 0.0 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 ABK74225.1 - 0.0018 18.3 0.0 0.0041 17.1 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 ABK74225.1 - 0.0094 15.4 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 ABK74225.1 - 0.034 13.8 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) TPMT PF05724.11 ABK74225.1 - 0.064 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) GerE PF00196.19 ABK74226.1 - 1.7e-16 59.5 0.5 2.8e-16 58.8 0.5 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 ABK74226.1 - 3.5e-05 23.4 0.6 0.00071 19.2 0.1 2.6 2 0 0 2 2 2 1 Sigma-70, region 4 Response_reg PF00072.24 ABK74226.1 - 7.1e-05 23.0 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HTH_23 PF13384.6 ABK74226.1 - 0.00021 21.0 0.2 0.0023 17.7 0.0 2.4 1 1 1 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.6 ABK74226.1 - 0.00095 18.9 0.1 0.0025 17.5 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 ABK74226.1 - 0.0062 16.5 0.5 0.055 13.5 0.1 2.6 1 1 1 2 2 2 1 Winged helix-turn helix HTH_40 PF14493.6 ABK74226.1 - 0.024 15.1 0.1 0.06 13.8 0.1 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 ABK74226.1 - 0.07 12.6 0.2 0.24 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 DoxX PF07681.12 ABK74226.1 - 0.11 13.1 0.7 17 6.1 0.2 2.4 2 0 0 2 2 2 0 DoxX HTH_7 PF02796.15 ABK74226.1 - 0.11 12.6 0.1 0.42 10.7 0.0 2.0 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase Nitroreductase PF00881.24 ABK74228.1 - 8.2e-28 97.6 0.8 2.6e-27 95.9 0.8 1.7 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 ABK74228.1 - 3e-09 36.8 0.1 0.0015 18.2 0.0 2.7 2 1 0 2 2 2 2 Putative TM nitroreductase Bac_luciferase PF00296.20 ABK74229.1 - 1.2e-42 146.5 0.7 1.5e-42 146.1 0.7 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase GntR PF00392.21 ABK74230.1 - 1.9e-15 56.2 0.3 3.8e-14 52.1 0.1 2.5 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family Aminotran_1_2 PF00155.21 ABK74230.1 - 1.6e-13 50.6 0.0 2.3e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DDE_Tnp_ISL3 PF01610.17 ABK74232.1 - 1.6e-64 217.9 0.0 2.1e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Transposase zf-ISL3 PF14690.6 ABK74232.1 - 1.1e-09 38.8 4.6 1.8e-09 38.1 2.5 2.5 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HTH_Tnp_ISL3 PF13542.6 ABK74232.1 - 2.4e-08 33.2 1.6 7e-08 31.8 1.6 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 PE-PPE PF08237.11 ABK74233.1 - 4.7e-08 32.9 0.5 0.0025 17.4 0.0 2.5 2 0 0 2 2 2 2 PE-PPE domain DUF948 PF06103.11 ABK74233.1 - 0.005 17.1 5.1 1.1 9.6 0.0 3.4 2 1 0 2 2 2 2 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 ABK74233.1 - 0.029 14.4 0.7 0.18 11.8 0.0 2.6 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus PGM_PMM_I PF02878.16 ABK74234.1 - 6.5e-41 139.3 0.0 1.6e-40 138.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 ABK74234.1 - 2.8e-22 79.3 0.2 7.8e-22 77.8 0.1 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 ABK74234.1 - 5.9e-19 68.3 0.2 1.2e-17 64.1 0.1 2.5 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 ABK74234.1 - 5.4e-08 32.9 0.1 1.6e-07 31.4 0.1 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain YjeF_N PF03853.15 ABK74234.1 - 0.04 13.8 0.4 0.45 10.4 0.1 2.6 2 1 0 2 2 2 0 YjeF-related protein N-terminus B12-binding PF02310.19 ABK74234.1 - 0.092 12.8 0.7 0.72 9.9 0.2 2.7 2 1 1 3 3 3 0 B12 binding domain Thiolase_N PF00108.23 ABK74235.1 - 1.1e-09 38.0 0.3 5.5e-09 35.8 0.0 2.2 2 1 0 2 2 2 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.26 ABK74235.1 - 1.3e-06 28.2 3.3 2e-06 27.6 1.6 1.8 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 ABK74235.1 - 4.8e-05 23.1 1.1 0.0035 17.1 0.3 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.22 ABK74235.1 - 0.072 13.1 0.1 2.5 8.2 0.0 2.6 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain Ribosomal_S7 PF00177.21 ABK74236.1 - 4.8e-63 211.3 0.2 5.3e-63 211.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e BPD_transp_2 PF02653.16 ABK74237.1 - 1.8e-43 148.7 49.9 1.8e-43 148.7 49.9 1.3 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component DDDD PF10161.9 ABK74237.1 - 0.31 10.8 0.1 0.31 10.8 0.1 2.9 3 0 0 3 3 3 0 Putative mitochondrial precursor protein PspC PF04024.12 ABK74237.1 - 2.3 8.1 7.5 0.99 9.3 0.1 3.5 4 0 0 4 4 4 0 PspC domain E1_dh PF00676.20 ABK74238.1 - 1.9e-56 191.2 0.0 4.7e-56 189.9 0.0 1.6 2 0 0 2 2 2 1 Dehydrogenase E1 component 2-oxoacid_dh PF00198.23 ABK74238.1 - 1e-55 188.7 0.0 1.7e-55 188.0 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Transket_pyr PF02779.24 ABK74238.1 - 2.4e-52 177.2 0.0 3.7e-52 176.6 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 ABK74238.1 - 2.7e-41 140.8 0.0 5.4e-41 139.8 0.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 ABK74238.1 - 4.3e-11 42.2 0.5 8.4e-11 41.3 0.5 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus TonB_N PF16031.5 ABK74238.1 - 0.16 12.5 17.9 0.39 11.2 17.9 1.6 1 0 0 1 1 1 0 TonB polyproline region DEC-1_N PF04625.13 ABK74238.1 - 1.3 8.0 6.8 2.4 7.1 6.8 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region GerE PF00196.19 ABK74239.1 - 1.8e-08 33.8 0.0 2.1e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 ABK74239.1 - 6.7e-05 22.5 1.1 0.00051 19.7 0.1 2.4 3 0 0 3 3 3 1 Sigma-70, region 4 HTH_30 PF13556.6 ABK74239.1 - 0.00019 21.2 0.3 0.00023 20.9 0.3 1.2 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.6 ABK74239.1 - 0.0056 16.8 0.2 0.0098 16.0 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain CENP-B_N PF04218.13 ABK74239.1 - 0.0061 16.2 0.0 0.0096 15.5 0.0 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_ISL3 PF13542.6 ABK74239.1 - 0.055 12.9 0.2 0.086 12.3 0.2 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_1 PF00126.27 ABK74239.1 - 0.064 13.2 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_24 PF13412.6 ABK74239.1 - 0.07 12.7 0.0 0.33 10.6 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_10 PF04967.12 ABK74239.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.5 1 1 0 1 1 1 0 HTH DNA binding domain OAD_gamma PF04277.13 ABK74240.1 - 0.57 10.8 0.0 0.57 10.8 0.0 3.8 5 0 0 5 5 5 0 Oxaloacetate decarboxylase, gamma chain MlaD PF02470.20 ABK74241.1 - 8.1e-17 61.3 0.9 1.5e-16 60.4 0.9 1.5 1 0 0 1 1 1 1 MlaD protein Mce4_CUP1 PF11887.8 ABK74241.1 - 0.00011 21.8 0.1 0.00017 21.1 0.1 1.3 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative DUF4404 PF14357.6 ABK74241.1 - 0.006 17.2 0.2 0.011 16.3 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4404) DUF3450 PF11932.8 ABK74241.1 - 0.034 13.5 0.3 0.14 11.5 0.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) PspA_IM30 PF04012.12 ABK74241.1 - 0.092 12.3 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 PspA/IM30 family DUF4411 PF14367.6 ABK74241.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4411) Bacillus_HBL PF05791.11 ABK74241.1 - 0.16 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF5624 PF18538.1 ABK74241.1 - 0.16 12.1 0.1 0.58 10.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) Vps5 PF09325.10 ABK74241.1 - 0.25 10.9 0.1 0.48 9.9 0.0 1.4 1 1 0 1 1 1 0 Vps5 C terminal like MFS_1 PF07690.16 ABK74242.1 - 1.5e-18 66.8 51.7 8.2e-15 54.6 22.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 ABK74242.1 - 2.4e-05 22.9 13.5 2.4e-05 22.9 13.5 2.1 1 1 1 2 2 2 1 Transmembrane secretion effector MFS_4 PF06779.14 ABK74242.1 - 0.025 13.9 37.3 0.042 13.2 37.3 1.3 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB BPD_transp_1 PF00528.22 ABK74243.1 - 2e-13 50.5 25.9 1e-12 48.2 25.9 1.9 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component ketoacyl-synt PF00109.26 ABK74243.1 - 0.029 13.9 0.1 0.051 13.2 0.1 1.3 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain DUF3796 PF12676.7 ABK74243.1 - 0.067 13.6 0.2 0.16 12.4 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) TruB_N PF01509.18 ABK74244.1 - 3.8e-54 183.1 0.0 5.2e-54 182.7 0.0 1.2 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C PF09142.11 ABK74244.1 - 1.1e-23 82.8 1.8 1.1e-23 82.8 1.8 2.5 4 0 0 4 4 4 1 tRNA Pseudouridine synthase II, C terminal TruB_C_2 PF16198.5 ABK74244.1 - 1.6e-11 44.2 1.1 2.7e-11 43.5 0.5 1.7 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain DKCLD PF08068.12 ABK74244.1 - 0.05 13.7 0.1 0.089 12.9 0.1 1.4 1 0 0 1 1 1 0 DKCLD (NUC011) domain Ribosomal_L16 PF00252.18 ABK74245.1 - 2.6e-47 160.2 0.1 2.9e-47 160.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e T2SSE_N PF05157.15 ABK74245.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein E, N-terminal domain Cutinase PF01083.22 ABK74246.1 - 1.2e-45 155.7 0.5 1.4e-45 155.4 0.5 1.0 1 0 0 1 1 1 1 Cutinase Abhydrolase_2 PF02230.16 ABK74246.1 - 7.5e-05 22.6 0.0 0.00014 21.8 0.0 1.5 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 ABK74246.1 - 0.011 15.5 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) p450 PF00067.22 ABK74247.1 - 1.4e-72 245.0 0.0 1.7e-72 244.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF5051 PF16473.5 ABK74248.1 - 1.2e-18 67.6 0.0 1.8e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease, RNase T-like TPR_19 PF14559.6 ABK74249.1 - 0.038 14.5 2.1 0.59 10.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 ABK74249.1 - 0.26 11.6 8.7 6.1 7.2 0.1 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 ABK74249.1 - 0.26 11.5 4.4 8.2 6.8 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 ABK74249.1 - 0.27 12.1 0.3 0.27 12.1 0.3 4.3 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 ABK74249.1 - 0.34 10.8 5.7 2.9 7.9 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 ABK74249.1 - 1.8 9.4 28.0 5.8 7.8 4.1 6.5 5 1 1 6 6 6 0 Tetratricopeptide repeat Potass_KdpF PF09604.10 ABK74250.1 - 0.0062 16.5 6.6 0.0082 16.1 6.6 1.2 1 0 0 1 1 1 1 F subunit of K+-transporting ATPase (Potass_KdpF) PIG-L PF02585.17 ABK74251.1 - 2.4e-24 86.4 0.0 3.2e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase SBP_bac_5 PF00496.22 ABK74252.1 - 4.5e-66 223.4 0.0 6.1e-66 222.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Aminotran_3 PF00202.21 ABK74253.1 - 6.6e-93 311.5 0.0 7.7e-93 311.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III VIT1 PF01988.19 ABK74254.1 - 2e-58 197.8 8.2 2.3e-58 197.6 8.2 1.0 1 0 0 1 1 1 1 VIT family NifQ PF04891.12 ABK74254.1 - 0.086 13.2 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 NifQ DUF4781 PF16013.5 ABK74254.1 - 2.7 6.7 5.1 0.32 9.7 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4781) DUF1942 PF09167.11 ABK74255.1 - 1.9e-54 182.9 1.8 1.9e-54 182.9 1.8 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1942) DUF4352 PF11611.8 ABK74255.1 - 0.031 14.5 0.0 0.11 12.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4352) SOG2 PF10428.9 ABK74255.1 - 3.1 6.9 6.7 3.4 6.7 6.7 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Ribonuclease_P PF00825.18 ABK74256.1 - 6.9e-23 80.8 0.0 7.8e-23 80.7 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease P Exo_endo_phos PF03372.23 ABK74257.1 - 1.2e-19 70.8 1.6 1.3e-19 70.6 1.6 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SBP_bac_3 PF00497.20 ABK74258.1 - 9.5e-39 133.1 0.0 1.1e-38 132.9 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.11 ABK74258.1 - 0.00046 20.2 0.0 0.001 19.0 0.0 1.6 1 1 0 1 1 1 1 NMT1/THI5 like Lig_chan-Glu_bd PF10613.9 ABK74258.1 - 0.00052 20.2 0.0 0.001 19.2 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Phosphonate-bd PF12974.7 ABK74258.1 - 0.022 14.4 0.0 0.079 12.5 0.0 1.9 1 1 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein His_Phos_1 PF00300.22 ABK74259.1 - 2.6e-36 125.2 0.0 3.4e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF4142 PF13628.6 ABK74259.1 - 0.11 12.7 0.3 0.22 11.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4142) DUF1707 PF08044.11 ABK74259.1 - 0.11 12.6 0.6 18 5.5 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1707) DUF1942 PF09167.11 ABK74260.1 - 2.4e-55 185.8 0.7 2.4e-55 185.8 0.7 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1942) DUF4352 PF11611.8 ABK74260.1 - 0.042 14.1 0.0 0.095 13.0 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4352) DNA_pol_viral_N PF00242.17 ABK74260.1 - 0.16 11.4 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Lipase_GDSL_2 PF13472.6 ABK74262.1 - 6.9e-13 49.4 1.9 8.4e-13 49.1 1.9 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ABK74262.1 - 7.7e-06 26.0 0.0 0.00011 22.3 0.0 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ABC_tran PF00005.27 ABK74263.1 - 1.4e-51 174.6 0.0 2.4e-29 102.6 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ABK74263.1 - 1.7e-14 54.4 1.6 1.8e-05 24.7 0.1 3.1 2 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK74263.1 - 1.4e-05 24.6 0.1 1.9 7.9 0.1 3.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_13 PF13166.6 ABK74263.1 - 0.00035 19.4 0.1 0.0086 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ABK74263.1 - 0.0055 16.4 0.6 0.017 14.8 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ABK74263.1 - 0.011 15.6 0.1 0.027 14.4 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 ABK74263.1 - 0.016 14.5 1.6 2.4 7.4 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin AAA_23 PF13476.6 ABK74263.1 - 0.019 15.5 0.6 0.059 13.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 ABK74263.1 - 0.029 14.1 0.0 0.042 13.6 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.6 ABK74263.1 - 0.062 13.7 4.1 0.12 12.8 0.2 2.7 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 ABK74263.1 - 0.58 10.4 2.9 1.6 9.0 0.1 3.0 3 1 0 3 3 3 0 AAA domain AAA_30 PF13604.6 ABK74263.1 - 7.2 6.3 6.9 2 8.1 0.3 3.0 2 2 0 2 2 2 0 AAA domain FCD PF07729.12 ABK74264.1 - 2.6e-18 66.7 2.6 2.6e-18 66.7 2.6 2.0 2 1 0 2 2 2 1 FCD domain GntR PF00392.21 ABK74264.1 - 7.8e-16 57.5 1.2 2.2e-15 56.1 1.2 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_11 PF08279.12 ABK74264.1 - 0.0003 20.7 0.1 0.00085 19.2 0.1 1.7 1 0 0 1 1 1 1 HTH domain HTH_24 PF13412.6 ABK74264.1 - 0.00047 19.7 0.4 0.0024 17.4 0.1 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_41 PF14502.6 ABK74264.1 - 0.001 18.7 0.0 0.0022 17.6 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 ABK74264.1 - 0.0032 17.3 0.8 0.016 15.1 0.1 2.3 2 0 0 2 2 2 1 MarR family HTH_20 PF12840.7 ABK74264.1 - 0.021 14.9 0.3 0.34 11.0 0.1 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain Fe_dep_repress PF01325.19 ABK74264.1 - 0.028 14.6 0.0 0.059 13.6 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_Crp_2 PF13545.6 ABK74264.1 - 0.047 13.7 0.1 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain TrmB PF01978.19 ABK74264.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HrcA_DNA-bdg PF03444.15 ABK74264.1 - 0.085 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Rrf2 PF02082.20 ABK74264.1 - 0.1 12.9 0.2 0.51 10.7 0.0 2.2 2 1 0 2 2 2 0 Transcriptional regulator HTH_5 PF01022.20 ABK74264.1 - 0.13 12.2 0.0 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family CoA_transf_3 PF02515.17 ABK74265.1 - 1.9e-79 267.5 0.0 2.1e-79 267.3 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III TetR_N PF00440.23 ABK74267.1 - 8.6e-12 44.7 0.2 1.7e-11 43.7 0.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 ABK74267.1 - 0.63 10.3 7.8 0.24 11.6 3.5 2.2 2 0 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal TetR_C_24 PF17932.1 ABK74268.1 - 1.2e-19 70.6 0.2 1.8e-19 70.1 0.2 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK74268.1 - 1.4e-14 53.6 0.4 3.9e-14 52.2 0.4 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_Tnp_1_2 PF13022.6 ABK74268.1 - 0.00036 20.7 0.0 0.0019 18.3 0.1 2.1 1 1 1 2 2 2 1 Helix-turn-helix of insertion element transposase TetR_C_5 PF08360.11 ABK74268.1 - 0.0019 18.4 0.0 0.0032 17.6 0.0 1.4 1 0 0 1 1 1 1 QacR-like protein, C-terminal region TetR_C_27 PF17935.1 ABK74268.1 - 0.0023 17.9 0.1 0.005 16.9 0.1 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_17 PF17922.1 ABK74268.1 - 0.018 15.1 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TetR_C_6 PF13977.6 ABK74268.1 - 0.022 14.9 0.4 0.2 11.9 0.1 2.2 2 0 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal TetR_C_10 PF16295.5 ABK74268.1 - 0.023 15.0 0.0 0.032 14.5 0.0 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TrmB PF01978.19 ABK74268.1 - 0.057 13.3 0.0 3.3 7.7 0.0 3.1 4 0 0 4 4 4 0 Sugar-specific transcriptional regulator TrmB Phage_AlpA PF05930.12 ABK74268.1 - 0.14 12.0 0.2 0.8 9.6 0.0 2.3 3 0 0 3 3 3 0 Prophage CP4-57 regulatory protein (AlpA) HTH_IclR PF09339.10 ABK74268.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain Dehydratase_SU PF02287.15 ABK74269.1 - 8.5e-57 190.9 0.4 1e-56 190.7 0.4 1.0 1 0 0 1 1 1 1 Dehydratase small subunit Tox-REase-3 PF15647.6 ABK74269.1 - 0.091 13.0 0.2 14 6.0 0.0 2.5 1 1 1 2 2 2 0 Restriction endonuclease fold toxin 3 EspB_PE PF18625.1 ABK74269.1 - 0.1 13.1 3.1 3 8.4 0.8 2.7 2 1 0 2 2 2 0 ESX-1 secreted protein B PE domain T7SS_ESX_EspC PF10824.8 ABK74269.1 - 0.15 12.6 2.7 0.42 11.1 2.7 1.9 1 1 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm DUF3135 PF11333.8 ABK74270.1 - 0.037 14.3 0.0 0.049 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) FKBP_C PF00254.28 ABK74271.1 - 1.5e-21 76.5 0.0 1.8e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase 3-dmu-9_3-mt PF06983.13 ABK74272.1 - 1.3e-35 122.4 0.0 1.7e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase WES_acyltransf PF03007.16 ABK74273.1 - 9.3e-89 297.7 1.3 1.3e-88 297.2 1.3 1.2 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 ABK74273.1 - 1.2e-37 129.1 0.0 4.2e-37 127.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1298) Condensation PF00668.20 ABK74273.1 - 2.9e-05 22.9 0.1 0.0063 15.2 0.1 2.1 2 0 0 2 2 2 2 Condensation domain Blt1 PF12754.7 ABK74273.1 - 0.041 14.2 0.0 0.075 13.3 0.0 1.4 1 0 0 1 1 1 0 Blt1 N-terminal domain DUF2613 PF11021.8 ABK74274.1 - 1.2e-23 83.0 1.1 1.3e-23 82.8 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2613) Tmemb_14 PF03647.13 ABK74274.1 - 0.03 15.1 0.1 0.03 15.0 0.1 1.1 1 0 0 1 1 1 0 Transmembrane proteins 14C CLP1_N PF16573.5 ABK74274.1 - 0.2 11.9 0.0 0.2 11.9 0.0 1.1 1 0 0 1 1 1 0 N-terminal beta-sandwich domain of polyadenylation factor TauE PF01925.19 ABK74275.1 - 8.1e-30 104.2 37.0 9.7e-30 103.9 37.0 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE MarR PF01047.22 ABK74276.1 - 4e-14 52.3 0.0 7.8e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 ABK74276.1 - 1.4e-10 40.9 1.5 2e-10 40.4 0.7 1.7 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 ABK74276.1 - 1.6e-05 25.3 0.1 8.2e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_20 PF12840.7 ABK74276.1 - 0.014 15.4 0.2 0.029 14.4 0.2 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain Rrf2 PF02082.20 ABK74276.1 - 0.016 15.5 0.1 0.028 14.8 0.1 1.4 1 0 0 1 1 1 0 Transcriptional regulator TrmB PF01978.19 ABK74276.1 - 0.026 14.4 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Fe_dep_repress PF01325.19 ABK74276.1 - 0.12 12.6 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_IclR PF09339.10 ABK74276.1 - 0.32 10.8 4.3 0.34 10.7 0.8 2.5 2 1 1 3 3 3 0 IclR helix-turn-helix domain SnoaL_2 PF12680.7 ABK74277.1 - 6.4e-09 36.4 3.2 9.2e-09 35.9 2.8 1.5 1 1 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 ABK74277.1 - 0.037 13.8 0.2 0.13 12.1 0.1 2.0 1 1 1 2 2 2 0 SnoaL-like polyketide cyclase Abhydrolase_1 PF00561.20 ABK74278.1 - 5.2e-14 52.5 0.5 7.5e-14 52.0 0.5 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK74278.1 - 9.9e-10 39.4 3.5 1.2e-09 39.1 3.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK74278.1 - 0.0024 17.2 0.1 0.0034 16.7 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF3235 PF11574.8 ABK74280.1 - 0.024 15.5 6.6 0.024 15.5 6.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) DUF5525 PF17663.1 ABK74280.1 - 0.099 10.7 5.8 0.11 10.6 5.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5525) adh_short_C2 PF13561.6 ABK74281.1 - 9.2e-43 146.5 0.7 2.3e-42 145.1 0.7 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK74281.1 - 9.3e-40 136.2 0.1 4.6e-39 133.9 0.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK74281.1 - 1.2e-08 35.1 0.5 9.4e-07 28.9 0.5 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK74281.1 - 0.003 17.1 0.2 0.014 14.9 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family LytR_C PF13399.6 ABK74281.1 - 0.023 15.6 0.1 0.062 14.3 0.0 1.8 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator RmlD_sub_bind PF04321.17 ABK74281.1 - 0.024 13.7 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DFP PF04127.15 ABK74281.1 - 0.039 13.8 0.1 0.053 13.4 0.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein ApbA PF02558.16 ABK74281.1 - 0.091 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PAP2 PF01569.21 ABK74282.1 - 0.11 12.3 19.1 0.76 9.5 19.0 2.3 1 1 0 1 1 1 0 PAP2 superfamily DUF2070 PF09843.9 ABK74282.1 - 0.12 10.7 5.2 0.13 10.5 5.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PAP2_C PF14360.6 ABK74282.1 - 0.13 12.8 4.5 0.07 13.7 1.9 1.9 2 0 0 2 2 2 0 PAP2 superfamily C-terminal DUF1270 PF06900.11 ABK74282.1 - 0.78 10.2 6.4 2.2 8.7 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1270) DUF212 PF02681.14 ABK74282.1 - 1 9.5 4.6 0.96 9.6 1.6 2.4 1 1 1 2 2 2 0 Divergent PAP2 family FA_desaturase PF00487.24 ABK74282.1 - 5.4 6.8 16.4 3.9 7.2 14.6 1.7 1 1 0 1 1 1 0 Fatty acid desaturase ABC_tran PF00005.27 ABK74283.1 - 6.8e-36 123.8 0.0 9e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK74283.1 - 4.4e-09 36.6 0.0 0.0002 21.3 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK74283.1 - 2e-07 30.7 0.4 1.2e-05 24.9 0.4 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ABK74283.1 - 1.8e-05 25.0 0.1 8.6e-05 22.8 0.1 2.0 2 1 0 2 2 1 1 AAA domain AAA_13 PF13166.6 ABK74283.1 - 4.1e-05 22.5 0.0 0.07 11.8 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ABK74283.1 - 9.3e-05 22.9 0.1 0.00018 21.9 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 ABK74283.1 - 0.00089 19.8 0.0 0.0015 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ABK74283.1 - 0.0013 18.7 0.1 0.0024 17.8 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 ABK74283.1 - 0.0015 18.2 0.0 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain PEPCK_ATP PF01293.20 ABK74283.1 - 0.0017 17.1 0.0 0.0025 16.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_30 PF13604.6 ABK74283.1 - 0.0034 17.1 0.3 0.0081 15.9 0.3 1.8 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 ABK74283.1 - 0.0051 16.6 0.4 0.098 12.4 0.1 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 ABK74283.1 - 0.0065 17.0 0.0 0.012 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ABK74283.1 - 0.0069 16.6 0.1 0.013 15.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 ABK74283.1 - 0.0094 16.4 0.2 0.18 12.2 0.2 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 ABK74283.1 - 0.013 15.4 0.0 0.031 14.2 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 ABK74283.1 - 0.019 14.7 0.1 0.032 13.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 ABK74283.1 - 0.02 14.6 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase ABC_ATPase PF09818.9 ABK74283.1 - 0.022 13.6 0.7 2.4 6.9 0.1 2.8 2 2 0 2 2 2 0 Predicted ATPase of the ABC class CobU PF02283.16 ABK74283.1 - 0.03 13.9 0.1 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase NB-ARC PF00931.22 ABK74283.1 - 0.051 12.8 0.1 0.12 11.5 0.1 1.5 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 ABK74283.1 - 0.064 13.7 0.1 0.21 12.0 0.0 1.9 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 ABK74283.1 - 0.08 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 ABK74283.1 - 0.084 13.1 0.1 0.3 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 ABK74283.1 - 0.088 12.6 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SbcCD_C PF13558.6 ABK74283.1 - 0.089 13.0 0.2 1 9.7 0.2 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit PhoH PF02562.16 ABK74283.1 - 0.095 12.1 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein APS_kinase PF01583.20 ABK74283.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase G-alpha PF00503.20 ABK74283.1 - 0.11 11.6 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_5 PF07728.14 ABK74283.1 - 0.11 12.4 0.1 0.65 10.0 0.0 2.2 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) Pur_DNA_glyco PF02245.16 ABK74283.1 - 0.13 11.7 0.0 6.9 6.1 0.0 2.3 2 0 0 2 2 2 0 Methylpurine-DNA glycosylase (MPG) AAA_17 PF13207.6 ABK74283.1 - 0.16 12.4 0.1 0.41 11.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_PrkA PF08298.11 ABK74283.1 - 0.17 10.8 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain Radical_SAM PF04055.21 ABK74284.1 - 1.2e-21 77.8 0.0 4.5e-21 75.9 0.0 1.9 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 ABK74284.1 - 0.049 13.8 0.0 0.19 11.9 0.0 1.9 1 1 0 1 1 1 0 4Fe-4S single cluster domain Pyr_redox_3 PF13738.6 ABK74287.1 - 3.3e-17 62.7 0.1 1.7e-15 57.1 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ABK74287.1 - 3.3e-15 55.5 0.0 2.7e-11 42.6 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 ABK74287.1 - 4e-15 55.8 0.0 6.3e-12 45.3 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ABK74287.1 - 2.7e-08 33.3 0.1 8.4e-07 28.4 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) SnoaL_2 PF12680.7 ABK74287.1 - 0.00098 19.7 0.9 0.0037 17.9 0.9 2.0 1 0 0 1 1 1 1 SnoaL-like domain Pyr_redox PF00070.27 ABK74287.1 - 0.0012 19.4 0.2 0.78 10.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ABK74287.1 - 0.0016 18.6 0.0 0.0053 17.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 ABK74287.1 - 0.0049 16.2 0.1 0.013 14.7 0.1 1.7 1 0 0 1 1 1 1 FAD binding domain TrkA_N PF02254.18 ABK74287.1 - 0.019 15.2 0.0 0.96 9.7 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_9 PF13454.6 ABK74287.1 - 0.026 14.5 1.1 3.1 7.8 0.0 3.1 4 0 0 4 4 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 ABK74287.1 - 0.036 13.1 0.1 6.1 5.8 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 ABK74287.1 - 0.04 13.0 0.3 0.34 9.9 0.6 2.1 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 ABK74287.1 - 0.07 12.7 0.7 2.7 7.5 0.0 2.9 3 0 0 3 3 3 0 FAD dependent oxidoreductase SnoaL_3 PF13474.6 ABK74287.1 - 0.14 12.4 0.4 0.38 11.0 0.1 1.9 2 0 0 2 2 1 0 SnoaL-like domain GIDA PF01134.22 ABK74287.1 - 0.21 10.6 0.3 17 4.3 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 ABK74287.1 - 0.23 10.1 0.2 3.3 6.3 0.0 2.4 3 0 0 3 3 3 0 HI0933-like protein DUF3090 PF11290.8 ABK74288.1 - 1.1e-67 227.2 0.0 1.2e-67 227.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3090) BPD_transp_1 PF00528.22 ABK74289.1 - 6.7e-20 71.6 15.8 6.7e-20 71.6 15.8 1.5 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component SecE PF00584.20 ABK74289.1 - 0.047 13.6 0.5 0.17 11.8 0.5 2.0 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex Asn_synthase PF00733.21 ABK74291.1 - 1.4e-86 291.4 0.0 1.8e-86 291.0 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 ABK74291.1 - 5.6e-43 145.8 0.0 1.1e-42 144.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 ABK74291.1 - 5.6e-40 136.6 0.0 7.4e-39 133.0 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase domain tRNA_Me_trans PF03054.16 ABK74291.1 - 0.035 12.9 0.0 0.052 12.3 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase DUF1933 PF09147.10 ABK74291.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1933) NAD_synthase PF02540.17 ABK74291.1 - 0.18 10.9 0.1 0.27 10.3 0.1 1.2 1 0 0 1 1 1 0 NAD synthase ADH_zinc_N PF00107.26 ABK74292.1 - 2.5e-13 50.1 0.0 3.9e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ABK74292.1 - 1.7e-08 34.2 0.0 2.6e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N PF08240.12 ABK74292.1 - 2.4e-06 27.4 0.0 4.6e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 ABK74292.1 - 0.0047 16.8 0.0 0.017 15.0 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase 2-Hacid_dh_C PF02826.19 ABK74292.1 - 0.0085 15.5 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 ABK74292.1 - 0.085 12.1 0.1 0.21 10.8 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ABK74292.1 - 0.22 12.1 0.2 0.43 11.2 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.22 ABK74294.1 - 1.1e-24 87.0 0.1 1e-20 74.0 0.1 3.0 2 1 0 2 2 2 2 Cytochrome P450 TauE PF01925.19 ABK74295.1 - 1.3e-22 80.6 35.7 1.6e-22 80.3 35.7 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE DUF3413 PF11893.8 ABK74295.1 - 0.39 9.9 4.0 0.087 12.0 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3413) TFIIB PF00382.19 ABK74295.1 - 0.83 9.7 3.0 12 6.0 0.0 2.5 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Bax1-I PF01027.20 ABK74295.1 - 1.7 8.4 20.8 0.55 10.0 8.6 2.3 1 1 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 CPP1-like PF11833.8 ABK74295.1 - 3.6 7.2 12.0 1.2 8.8 4.4 2.4 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like HNH_5 PF14279.6 ABK74296.1 - 3e-07 30.2 0.9 5.6e-07 29.3 0.9 1.5 1 1 0 1 1 1 1 HNH endonuclease HNH PF01844.23 ABK74296.1 - 3e-06 27.3 0.2 4.5e-06 26.7 0.2 1.3 1 0 0 1 1 1 1 HNH endonuclease DUF3716 PF12511.8 ABK74296.1 - 0.021 14.8 4.3 0.032 14.3 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) NMT1 PF09084.11 ABK74297.1 - 1.3e-22 80.8 0.0 1.7e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 ABK74297.1 - 5e-13 49.3 0.7 2.8e-06 27.2 0.1 2.1 2 0 0 2 2 2 2 NMT1-like family TPR_5 PF12688.7 ABK74298.1 - 7.2e-05 23.0 0.2 0.00018 21.7 0.2 1.6 1 0 0 1 1 1 1 Tetratrico peptide repeat TPR_12 PF13424.6 ABK74298.1 - 0.0067 16.7 11.8 1.1 9.6 0.2 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 ABK74298.1 - 0.0079 16.7 12.8 3.3 8.3 0.2 3.6 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 ABK74298.1 - 0.0084 16.7 22.1 0.52 11.0 1.1 4.0 2 2 1 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ABK74298.1 - 0.0098 16.1 1.1 0.45 10.8 0.0 2.9 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 HemY_N PF07219.13 ABK74298.1 - 0.3 11.3 4.7 3.8 7.7 3.9 2.5 1 1 1 2 2 2 0 HemY protein N-terminus TPR_2 PF07719.17 ABK74298.1 - 1 9.7 11.5 2.6 8.4 0.6 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat AhpC-TSA PF00578.21 ABK74299.1 - 1.1e-40 138.4 0.0 1.3e-40 138.2 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ABK74299.1 - 1.9e-32 112.0 0.0 2.1e-32 111.8 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 ABK74299.1 - 8.4e-06 25.9 0.0 1.7e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF899 PF05988.12 ABK74299.1 - 8.9e-05 22.1 0.0 0.0001 21.9 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) SCO1-SenC PF02630.14 ABK74299.1 - 0.0011 18.9 0.0 0.0017 18.2 0.0 1.4 1 1 0 1 1 1 1 SCO1/SenC GSHPx PF00255.19 ABK74299.1 - 0.0019 17.8 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione peroxidase CM_2 PF01817.21 ABK74300.1 - 4.6e-10 39.7 0.0 2.6e-08 34.1 0.0 2.2 2 0 0 2 2 2 2 Chorismate mutase type II HTH_18 PF12833.7 ABK74301.1 - 8.9e-24 83.6 1.0 1.7e-23 82.7 1.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 ABK74301.1 - 7.9e-17 60.9 0.0 4.9e-09 36.1 0.0 2.3 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family AraC_binding PF02311.19 ABK74301.1 - 5.1e-14 52.3 0.0 1e-13 51.4 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain HTH_31 PF13560.6 ABK74301.1 - 0.0072 16.6 1.6 3.8 7.9 0.1 3.1 2 0 0 2 2 2 2 Helix-turn-helix domain Cupin_6 PF12852.7 ABK74301.1 - 0.017 14.8 2.1 0.062 13.0 1.9 2.2 1 1 0 1 1 1 0 Cupin Cupin_2 PF07883.11 ABK74301.1 - 0.05 13.3 0.1 0.11 12.3 0.1 1.6 1 1 0 1 1 1 0 Cupin domain GNVR PF13807.6 ABK74301.1 - 0.074 13.0 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase MR_MLE_C PF13378.6 ABK74303.1 - 7.8e-29 100.8 3.5 1.1e-28 100.3 3.5 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like Enolase_like_N PF18374.1 ABK74303.1 - 3.4e-27 93.6 1.5 5.7e-27 92.9 1.5 1.4 1 0 0 1 1 1 1 Enolase N-terminal domain-like MAAL_C PF07476.11 ABK74303.1 - 0.16 11.1 0.1 0.26 10.4 0.1 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Peptidase_M23 PF01551.22 ABK74304.1 - 1.8e-15 56.9 0.1 2.2e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M23 Abhydrolase_1 PF00561.20 ABK74305.1 - 9.8e-27 94.2 0.3 3.6e-25 89.1 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK74305.1 - 6.2e-22 79.3 1.0 7.3e-22 79.1 1.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK74305.1 - 1.4e-15 57.2 0.1 4.6e-15 55.5 0.1 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 ABK74305.1 - 0.00026 20.2 0.0 0.00036 19.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Ndr PF03096.14 ABK74305.1 - 0.0054 15.5 0.0 0.0085 14.8 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_2 PF02230.16 ABK74305.1 - 0.06 13.1 0.0 0.32 10.8 0.2 2.0 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Esterase PF00756.20 ABK74305.1 - 0.14 11.7 0.0 0.39 10.3 0.0 1.6 1 1 0 2 2 2 0 Putative esterase DUF1100 PF06500.11 ABK74305.1 - 0.2 10.4 0.0 0.27 10.0 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Methyltransf_11 PF08241.12 ABK74306.1 - 1.5e-24 86.5 0.0 2.2e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABK74306.1 - 1.5e-22 80.1 0.1 2.1e-22 79.6 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABK74306.1 - 1.4e-17 63.9 0.0 2e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ABK74306.1 - 2.1e-17 63.3 0.0 5.2e-17 62.0 0.0 1.5 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 ABK74306.1 - 7.8e-15 55.1 0.0 1.2e-14 54.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK74306.1 - 1.1e-13 51.8 0.0 1.4e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ABK74306.1 - 3.8e-07 30.1 0.0 5.5e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 ABK74306.1 - 1.4e-06 28.0 0.0 1.9e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CMAS PF02353.20 ABK74306.1 - 0.00035 20.0 0.0 0.00043 19.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 ABK74306.1 - 0.00077 19.0 0.0 0.0028 17.2 0.0 1.8 1 1 0 1 1 1 1 Putative methyltransferase GCD14 PF08704.10 ABK74306.1 - 0.0009 19.0 0.0 0.0012 18.6 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit FtsJ PF01728.19 ABK74306.1 - 0.0012 19.0 0.0 0.0018 18.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase NodS PF05401.11 ABK74306.1 - 0.0034 17.0 0.0 0.005 16.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 ABK74306.1 - 0.011 15.4 0.0 0.019 14.5 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_8 PF05148.15 ABK74306.1 - 0.028 14.3 0.0 0.34 10.7 0.0 2.0 1 1 0 1 1 1 0 Hypothetical methyltransferase ADH_zinc_N PF00107.26 ABK74306.1 - 0.038 14.0 0.2 0.071 13.1 0.2 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase RrnaAD PF00398.20 ABK74306.1 - 0.23 10.5 0.0 0.26 10.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NAD_binding_1 PF00175.21 ABK74307.1 - 1.3e-13 51.5 0.0 2.5e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Fer2 PF00111.27 ABK74307.1 - 3.1e-12 46.3 0.4 5.6e-12 45.5 0.4 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FAD_binding_6 PF00970.24 ABK74307.1 - 6.9e-09 36.0 0.0 1.2e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 ABK74307.1 - 0.00017 21.8 0.0 0.0029 17.7 0.0 2.1 1 1 1 2 2 2 1 Ferric reductase NAD binding domain adh_short_C2 PF13561.6 ABK74308.1 - 1.5e-69 234.1 8.2 1.8e-69 233.8 8.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK74308.1 - 8e-59 198.4 7.8 9.4e-59 198.1 7.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK74308.1 - 7.3e-23 81.4 5.0 1e-22 80.9 5.0 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 ABK74308.1 - 0.0011 18.1 0.6 0.0014 17.7 0.6 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ABK74308.1 - 0.032 13.7 1.6 0.1 12.0 1.6 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 ABK74308.1 - 0.1 12.5 2.8 0.071 13.0 0.7 1.9 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RNA_pol PF00940.19 ABK74308.1 - 0.19 10.5 0.0 0.27 10.0 0.0 1.1 1 0 0 1 1 1 0 DNA-dependent RNA polymerase DUF1330 PF07045.11 ABK74309.1 - 6.6e-33 112.9 0.0 7.3e-33 112.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1330) ABC_tran PF00005.27 ABK74310.1 - 2.9e-31 108.8 0.0 3.9e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK74310.1 - 0.00029 20.7 0.1 0.04 13.7 0.3 2.1 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ABK74310.1 - 0.00073 19.2 0.1 0.0013 18.4 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 ABK74310.1 - 0.0018 18.7 0.3 0.0051 17.2 0.2 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ABK74310.1 - 0.0019 18.5 0.1 0.0096 16.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 ABK74310.1 - 0.0021 18.1 0.5 0.0048 17.0 0.2 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ABK74310.1 - 0.003 17.5 0.0 0.0045 16.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 ABK74310.1 - 0.0069 15.9 0.1 0.43 10.0 0.1 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 ABK74310.1 - 0.0071 16.8 0.2 0.086 13.3 0.2 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 ABK74310.1 - 0.0073 16.8 0.1 0.012 16.2 0.1 1.2 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 ABK74310.1 - 0.017 14.3 0.0 0.034 13.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Rad17 PF03215.15 ABK74310.1 - 0.025 14.5 0.0 0.053 13.4 0.0 1.5 2 0 0 2 2 1 0 Rad17 P-loop domain Mg_chelatase PF01078.21 ABK74310.1 - 0.047 13.1 0.0 0.087 12.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI FeoB_N PF02421.18 ABK74310.1 - 0.062 12.8 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B ATPase_2 PF01637.18 ABK74310.1 - 0.07 13.0 0.2 0.56 10.1 0.0 2.3 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 ABK74310.1 - 0.07 12.7 0.8 0.26 10.8 0.1 2.2 1 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ABK74310.1 - 0.085 13.3 0.1 0.36 11.2 0.0 2.0 2 1 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 ABK74310.1 - 0.13 12.0 0.1 0.5 10.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.15 ABK74310.1 - 0.25 10.1 0.0 6 5.6 0.1 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein NTPase_1 PF03266.15 ABK74310.1 - 0.28 11.1 1.3 7.2 6.5 0.1 2.5 2 1 0 2 2 2 0 NTPase Cyt_bd_oxida_I PF01654.17 ABK74312.1 - 1.4e-115 386.3 24.3 1.7e-115 386.0 24.3 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit I UPF0370 PF13980.6 ABK74312.1 - 0.12 12.4 1.5 7 6.8 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) ABC_tran PF00005.27 ABK74313.1 - 6e-36 124.0 0.0 7.8e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK74313.1 - 2.4e-10 40.7 0.1 0.00061 19.7 0.1 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK74313.1 - 2.1e-06 27.4 0.2 0.00031 20.3 0.1 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 ABK74313.1 - 2.1e-06 27.5 0.2 5.1e-06 26.2 0.2 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ABK74313.1 - 8.6e-05 23.0 0.0 0.00012 22.5 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ABK74313.1 - 0.00015 22.0 1.6 0.005 17.1 1.6 2.3 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 ABK74313.1 - 0.0003 21.2 0.0 0.03 14.7 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 ABK74313.1 - 0.00066 19.4 0.1 0.0028 17.4 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_5 PF07728.14 ABK74313.1 - 0.00086 19.3 0.1 0.18 11.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 ABK74313.1 - 0.0018 17.7 0.0 0.14 11.5 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 ABK74313.1 - 0.011 15.2 0.2 1.5 8.2 0.1 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_28 PF13521.6 ABK74313.1 - 0.011 15.9 0.1 0.039 14.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 ABK74313.1 - 0.013 16.1 0.1 0.028 14.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ABK74313.1 - 0.019 15.1 0.0 0.042 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ABK74313.1 - 0.068 13.7 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 ABK74313.1 - 0.07 12.8 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.6 ABK74313.1 - 0.071 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 ABK74313.1 - 0.072 12.3 0.0 0.12 11.6 0.0 1.3 1 1 0 1 1 1 0 NB-ARC domain RsgA_GTPase PF03193.16 ABK74313.1 - 0.074 12.9 0.3 0.15 12.0 0.0 1.5 2 0 0 2 2 1 0 RsgA GTPase SbcCD_C PF13558.6 ABK74313.1 - 0.076 13.3 0.3 1.4 9.2 0.3 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 ABK74313.1 - 0.09 12.5 0.4 0.28 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 ABK74313.1 - 0.093 12.2 0.1 0.24 10.8 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit NACHT PF05729.12 ABK74313.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.6 ABK74313.1 - 0.14 12.4 0.2 0.44 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 ABK74313.1 - 0.26 9.9 0.0 10 4.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 ABK74313.1 - 0.29 10.8 0.0 0.55 9.9 0.0 1.4 2 0 0 2 2 2 0 AAA ATPase domain Glycolipid_bind PF06475.11 ABK74314.1 - 5e-51 172.7 0.0 5.5e-51 172.6 0.0 1.0 1 0 0 1 1 1 1 Putative glycolipid-binding LRR_11 PF18831.1 ABK74314.1 - 0.16 11.6 0.1 0.3 10.7 0.1 1.4 1 0 0 1 1 1 0 Leucine-rich repeat AMP-binding PF00501.28 ABK74315.1 - 9.2e-56 189.2 0.0 1.2e-55 188.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 ABK74315.1 - 1.2e-15 57.1 0.9 3.5e-15 55.6 0.5 2.0 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 ABK74315.1 - 5e-10 40.2 0.0 1.3e-09 38.9 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Abhydrolase_6 PF12697.7 ABK74316.1 - 7.2e-06 26.8 0.1 1e-05 26.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ABK74316.1 - 0.00055 19.7 0.0 0.0096 15.6 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold CBP_BcsQ PF06564.12 ABK74317.1 - 0.071 12.6 0.5 1 8.8 0.0 2.2 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ AAA_31 PF13614.6 ABK74317.1 - 0.3 11.0 0.4 5.4 6.9 0.1 2.2 2 0 0 2 2 2 0 AAA domain Esterase PF00756.20 ABK74318.1 - 6.3e-63 212.7 0.0 8.2e-63 212.4 0.0 1.1 1 0 0 1 1 1 1 Putative esterase LysM PF01476.20 ABK74318.1 - 3e-23 81.6 0.0 2.7e-06 27.3 0.0 3.3 3 0 0 3 3 3 3 LysM domain Phage_tail_X PF05489.12 ABK74318.1 - 0.0025 17.5 10.4 1.8 8.3 0.1 4.5 3 1 2 5 5 5 3 Phage Tail Protein X Abhydrolase_1 PF00561.20 ABK74318.1 - 0.0082 15.8 0.1 0.015 15.0 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ABK74318.1 - 0.071 12.4 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Asp2 PF16929.5 ABK74318.1 - 0.15 11.0 1.1 0.21 10.5 1.1 1.1 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter Abhydrolase_2 PF02230.16 ABK74318.1 - 0.37 10.6 2.1 6.6 6.5 2.1 2.1 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase DapB_N PF01113.20 ABK74319.1 - 6.9e-09 35.9 0.4 1.5e-08 34.8 0.4 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus CoA_binding PF02629.19 ABK74319.1 - 0.0052 17.4 0.3 0.016 15.9 0.3 1.8 1 0 0 1 1 1 1 CoA binding domain GFO_IDH_MocA PF01408.22 ABK74319.1 - 0.015 16.2 0.0 0.029 15.2 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold ApbA PF02558.16 ABK74319.1 - 0.034 13.8 0.2 0.066 12.8 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AP_endonuc_2 PF01261.24 ABK74319.1 - 0.038 13.4 0.0 0.39 10.1 0.0 2.1 1 1 0 2 2 2 0 Xylose isomerase-like TIM barrel Sacchrp_dh_NADP PF03435.18 ABK74319.1 - 0.069 13.4 0.0 3.8 7.8 0.1 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 ABK74319.1 - 0.1 12.6 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Aldo_ket_red PF00248.21 ABK74320.1 - 1.1e-72 244.7 0.0 1.4e-72 244.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PE-PPE PF08237.11 ABK74321.1 - 2.1e-66 223.7 0.0 2.9e-66 223.3 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Whib PF02467.16 ABK74322.1 - 9.1e-27 93.4 3.4 1.2e-26 93.1 3.4 1.2 1 0 0 1 1 1 1 Transcription factor WhiB Polyketide_cyc2 PF10604.9 ABK74323.1 - 1.5e-21 77.2 0.0 1.6e-21 77.0 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 ABK74323.1 - 0.00045 20.4 0.7 0.012 15.8 0.7 2.1 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport NMO PF03060.15 ABK74324.1 - 9e-95 317.8 4.2 1.1e-94 317.5 4.2 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 ABK74324.1 - 4.3e-07 29.3 1.8 6.7e-07 28.6 1.8 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 ABK74324.1 - 8.1e-06 25.1 0.2 0.00024 20.2 0.2 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.21 ABK74324.1 - 8.6e-06 25.2 0.0 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.21 ABK74324.1 - 5.7e-05 22.7 0.4 0.00017 21.1 0.3 1.7 2 0 0 2 2 2 1 Histidine biosynthesis protein TMP-TENI PF02581.17 ABK74324.1 - 0.014 14.7 0.3 0.037 13.3 0.3 1.7 1 0 0 1 1 1 0 Thiamine monophosphate synthase G3P_antiterm PF04309.12 ABK74324.1 - 0.046 13.1 0.1 0.13 11.7 0.1 1.7 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator NanE PF04131.14 ABK74324.1 - 0.054 12.7 0.1 0.096 11.9 0.1 1.3 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Glu_synthase PF01645.17 ABK74324.1 - 0.1 11.7 0.6 0.17 11.0 0.6 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase Lipase_GDSL_2 PF13472.6 ABK74324.1 - 0.56 10.6 5.4 8.6 6.7 4.8 2.2 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Transp_cyt_pur PF02133.15 ABK74325.1 - 1.8e-40 139.1 46.6 2.1e-40 138.9 46.6 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin NB PF04159.13 ABK74325.1 - 1.2 9.2 2.8 3.3 7.8 0.6 2.3 2 0 0 2 2 2 0 NB glycoprotein MttA_Hcf106 PF02416.16 ABK74326.1 - 1.7e-21 75.3 0.0 1.8e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 mttA/Hcf106 family DJ-1_PfpI PF01965.24 ABK74328.1 - 1.6e-49 167.9 0.1 1.8e-49 167.7 0.1 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family Catalase_C PF18011.1 ABK74328.1 - 1.1e-05 25.1 0.0 1.7e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain found in long catalases MctB PF11382.8 ABK74328.1 - 0.0034 17.1 4.3 0.0063 16.3 0.5 2.3 2 1 0 2 2 2 1 Copper transport outer membrane protein, MctB GATase_5 PF13507.6 ABK74328.1 - 0.015 14.4 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DUF3931 PF13082.6 ABK74328.1 - 0.14 12.4 0.0 0.34 11.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3931) PAS PF00989.25 ABK74329.1 - 1.6e-13 50.6 0.2 3.6e-13 49.5 0.0 1.7 2 1 0 2 2 2 1 PAS fold PAS_4 PF08448.10 ABK74329.1 - 8.5e-13 48.5 0.0 1.3e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 ABK74329.1 - 2.6e-12 46.9 0.0 3.7e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 ABK74329.1 - 2.3e-10 40.2 0.0 4.8e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 ABK74329.1 - 9e-05 22.7 0.0 0.00014 22.1 0.0 1.3 1 0 0 1 1 1 1 PAS fold MLTR_LBD PF17765.1 ABK74329.1 - 0.0082 16.3 4.4 0.048 13.8 0.1 2.5 1 1 2 3 3 3 1 MmyB-like transcription regulator ligand binding domain PAS_7 PF12860.7 ABK74329.1 - 0.0088 16.2 0.0 0.016 15.3 0.0 1.6 1 1 1 2 2 2 1 PAS fold PsaM PF07465.13 ABK74330.1 - 0.07 12.9 2.2 0.07 12.9 2.2 2.6 2 0 0 2 2 2 0 Photosystem I protein M (PsaM) DUF2207 PF09972.9 ABK74330.1 - 1.5 7.5 5.0 1.8 7.2 5.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) GatB_N PF02934.15 ABK74332.1 - 6.7e-104 347.1 0.0 8.8e-104 346.7 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 ABK74332.1 - 5.4e-39 133.4 0.2 7.5e-39 133.0 0.2 1.2 1 0 0 1 1 1 1 GatB domain YqeY PF09424.10 ABK74332.1 - 0.17 12.0 0.6 0.39 10.8 0.6 1.6 1 0 0 1 1 1 0 Yqey-like protein NAD_binding_10 PF13460.6 ABK74333.1 - 4.3e-08 33.3 0.2 9.6e-08 32.1 0.1 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ABK74333.1 - 2.5e-06 27.1 0.0 6.9e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 ABK74333.1 - 0.00018 21.1 0.0 0.00027 20.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 ABK74333.1 - 0.0033 16.5 0.0 0.0064 15.5 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ABK74333.1 - 0.034 13.3 0.0 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain RecA PF00154.21 ABK74334.1 - 8.6e-144 477.8 1.3 1.1e-143 477.5 1.3 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 ABK74334.1 - 6.6e-10 38.7 0.0 1.5e-09 37.5 0.0 1.5 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 ABK74334.1 - 6.1e-09 35.6 0.3 3e-07 30.0 0.3 2.6 1 1 0 1 1 1 1 KaiC ATPase_2 PF01637.18 ABK74334.1 - 0.00019 21.5 0.0 0.00042 20.3 0.0 1.7 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 ABK74334.1 - 0.00026 20.8 0.0 0.00047 19.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 ABK74334.1 - 0.0022 17.6 0.6 0.043 13.4 0.0 2.3 1 1 0 2 2 2 1 AAA domain CobU PF02283.16 ABK74334.1 - 0.0038 16.8 0.0 0.0063 16.1 0.0 1.3 1 0 0 1 1 1 1 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA PF00004.29 ABK74334.1 - 0.0064 16.9 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ABK74334.1 - 0.1 13.0 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AXE1 PF05448.12 ABK74335.1 - 0.00011 21.0 0.0 0.00023 19.9 0.0 1.5 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 ABK74335.1 - 0.00013 22.7 8.7 0.00013 22.7 8.7 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1100 PF06500.11 ABK74335.1 - 0.001 18.0 0.0 0.0036 16.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) DLH PF01738.18 ABK74335.1 - 0.0047 16.5 0.0 0.0083 15.7 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 ABK74335.1 - 0.035 13.6 0.0 0.094 12.2 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 ABK74335.1 - 0.067 12.8 0.0 0.24 11.0 0.0 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold Acyl_transf_3 PF01757.22 ABK74336.1 - 4.6e-32 111.4 35.6 5.2e-32 111.2 35.6 1.0 1 0 0 1 1 1 1 Acyltransferase family Gemini_mov PF01708.16 ABK74336.1 - 0.057 13.2 0.4 0.057 13.2 0.4 2.4 2 0 0 2 2 2 0 Geminivirus putative movement protein UcrQ PF02939.16 ABK74336.1 - 1.1 9.2 5.0 5.6 7.0 0.1 3.0 3 0 0 3 3 3 0 UcrQ family Formyl_trans_N PF00551.19 ABK74337.1 - 7e-38 130.2 0.0 8.8e-38 129.8 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 ABK74337.1 - 6.1e-10 38.7 0.0 1.7e-09 37.3 0.0 1.8 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 ABK74337.1 - 0.0079 16.8 0.0 0.017 15.7 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 ABK74337.1 - 0.055 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 ACT domain PPK2 PF03976.14 ABK74337.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) Abhydrolase_6 PF12697.7 ABK74338.1 - 2.7e-24 87.0 8.2 4.2e-24 86.4 8.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK74338.1 - 3.4e-10 39.6 0.1 9.8e-10 38.1 0.1 1.7 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ABK74338.1 - 4.1e-06 26.6 0.9 6e-05 22.8 0.9 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 ABK74338.1 - 5.4e-05 23.0 0.1 8.5e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 ABK74338.1 - 7.5e-05 22.6 0.3 0.055 13.3 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase Thioesterase PF00975.20 ABK74338.1 - 0.012 15.7 0.2 0.03 14.4 0.2 1.7 1 1 0 1 1 1 0 Thioesterase domain LytR_cpsA_psr PF03816.14 ABK74340.1 - 1.4e-46 158.4 0.0 3.7e-46 157.1 0.0 1.7 1 0 0 1 1 1 1 Cell envelope-related transcriptional attenuator domain LytR_C PF13399.6 ABK74340.1 - 1.1e-16 61.5 0.8 1.1e-16 61.5 0.8 2.0 2 0 0 2 2 2 1 LytR cell envelope-related transcriptional attenuator AMP-binding PF00501.28 ABK74342.1 - 1.7e-68 231.2 0.0 2e-68 231.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Alpha-amylase PF00128.24 ABK74343.1 - 2e-43 149.2 0.0 1.6e-40 139.8 0.0 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF3459 PF11941.8 ABK74343.1 - 1.6e-05 25.1 1.8 2.5e-05 24.5 0.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3459) CH_2 PF06294.11 ABK74343.1 - 0.071 13.2 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 CH-like domain in sperm protein 60KD_IMP PF02096.20 ABK74344.1 - 2.5e-48 164.1 2.9 3.6e-48 163.6 2.9 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein SicP-binding PF09119.10 ABK74344.1 - 0.05 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 SicP binding DUF2207 PF09972.9 ABK74344.1 - 0.99 8.1 3.0 4.5 5.9 0.4 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF1757 PF08560.10 ABK74345.1 - 0.0069 16.5 0.1 0.0075 16.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1757) TetR_N PF00440.23 ABK74346.1 - 3.9e-11 42.5 0.0 6.6e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_1 PF02909.17 ABK74346.1 - 2e-05 24.5 0.0 3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain adh_short PF00106.25 ABK74347.1 - 5.2e-46 156.6 2.2 6.8e-46 156.2 2.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK74347.1 - 8e-36 123.8 2.7 1.1e-35 123.3 2.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK74347.1 - 2.2e-14 53.8 2.4 3.6e-14 53.1 2.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK74347.1 - 0.00084 18.9 1.5 0.0019 17.7 1.5 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ABK74347.1 - 0.021 13.9 0.1 0.028 13.6 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1776 PF08643.10 ABK74347.1 - 0.039 13.3 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Methyltransf_25 PF13649.6 ABK74347.1 - 0.059 14.1 0.2 0.16 12.6 0.2 1.8 1 0 0 1 1 1 0 Methyltransferase domain UPF0146 PF03686.13 ABK74347.1 - 0.092 12.6 0.2 0.17 11.8 0.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) TetR_N PF00440.23 ABK74348.1 - 4.7e-15 55.1 0.3 1.3e-14 53.7 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 ABK74348.1 - 0.0046 17.3 1.0 0.0046 17.3 1.0 2.1 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain Response_reg PF00072.24 ABK74349.1 - 2.4e-24 85.7 0.1 3.8e-24 85.0 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 ABK74349.1 - 2.4e-16 59.0 0.1 4.2e-16 58.2 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 ABK74349.1 - 8.5e-06 25.4 0.1 1.9e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 ABK74349.1 - 0.0052 16.3 0.1 0.01 15.3 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_24 PF13412.6 ABK74349.1 - 0.0056 16.2 0.1 0.013 15.1 0.1 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_40 PF14493.6 ABK74349.1 - 0.013 16.0 0.0 0.029 14.8 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_38 PF13936.6 ABK74349.1 - 0.017 14.9 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 ABK74349.1 - 0.026 14.3 0.0 0.059 13.2 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Fas_alpha_ACP PF18325.1 ABK74349.1 - 0.11 12.9 0.0 0.16 12.3 0.0 1.4 1 1 0 1 1 1 0 Fatty acid synthase subunit alpha Acyl carrier domain Arc_PepC PF06819.11 ABK74349.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminal Domain HTH_Tnp_ISL3 PF13542.6 ABK74349.1 - 0.15 11.5 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_5 PF01022.20 ABK74350.1 - 9.8e-16 57.4 0.1 1.7e-15 56.6 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 ABK74350.1 - 8.7e-15 54.5 0.2 1.7e-14 53.6 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 ABK74350.1 - 4.5e-09 36.1 0.9 6.8e-09 35.5 0.9 1.2 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 ABK74350.1 - 4.3e-05 23.2 0.2 9.2e-05 22.2 0.2 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_24 PF13412.6 ABK74350.1 - 4.4e-05 23.0 0.0 7.6e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_27 PF13463.6 ABK74350.1 - 0.00052 20.4 0.3 0.00083 19.8 0.3 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_28 PF13518.6 ABK74350.1 - 0.00055 20.0 0.1 0.041 14.0 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain MarR PF01047.22 ABK74350.1 - 0.00061 19.7 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_45 PF14947.6 ABK74350.1 - 0.00093 19.1 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix TrmB PF01978.19 ABK74350.1 - 0.0014 18.5 0.0 0.002 18.0 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Fe_dep_repress PF01325.19 ABK74350.1 - 0.0036 17.5 0.2 0.0098 16.1 0.1 1.8 2 1 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain HTH_11 PF08279.12 ABK74350.1 - 0.014 15.4 0.2 0.02 14.8 0.2 1.5 1 1 0 1 1 1 0 HTH domain HTH_1 PF00126.27 ABK74350.1 - 0.015 15.2 0.3 0.049 13.6 0.3 2.0 2 1 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family LexA_DNA_bind PF01726.16 ABK74350.1 - 0.032 14.0 0.1 0.23 11.2 0.0 2.2 1 1 1 2 2 2 0 LexA DNA binding domain HTH_34 PF13601.6 ABK74350.1 - 0.035 14.3 0.0 0.064 13.4 0.0 1.5 2 0 0 2 2 1 0 Winged helix DNA-binding domain HTH_Crp_2 PF13545.6 ABK74350.1 - 0.037 14.0 0.3 0.052 13.5 0.3 1.3 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Rrf2 PF02082.20 ABK74350.1 - 0.05 14.0 0.0 0.076 13.4 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator HTH_9 PF08221.11 ABK74350.1 - 0.088 12.9 0.2 0.14 12.3 0.2 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain IGPS PF00218.21 ABK74351.1 - 9.4e-81 270.7 0.0 1.1e-80 270.5 0.0 1.0 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase FMN_dh PF01070.18 ABK74351.1 - 4.7e-05 22.6 2.3 0.0076 15.3 2.3 2.4 1 1 2 3 3 3 2 FMN-dependent dehydrogenase NanE PF04131.14 ABK74351.1 - 0.0022 17.2 0.4 0.3 10.3 0.3 2.8 2 1 0 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 ABK74351.1 - 0.0034 16.9 1.6 0.3 10.5 0.0 2.8 1 1 2 3 3 3 1 Histidine biosynthesis protein OMPdecase PF00215.24 ABK74351.1 - 0.0053 16.4 0.0 0.006 16.2 0.0 1.2 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family QRPTase_C PF01729.19 ABK74351.1 - 0.036 13.9 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain CMD PF02627.20 ABK74352.1 - 1.7e-12 47.2 0.4 1.7e-12 47.2 0.4 2.1 1 1 0 2 2 2 1 Carboxymuconolactone decarboxylase family Rsm22 PF09243.10 ABK74352.1 - 0.066 12.5 0.1 0.39 10.0 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial small ribosomal subunit Rsm22 ILVD_EDD PF00920.21 ABK74353.1 - 1.7e-214 713.3 0.3 1.9e-214 713.1 0.3 1.0 1 0 0 1 1 1 1 Dehydratase family Mannitol_dh_C PF08125.13 ABK74354.1 - 1.1e-59 201.9 0.0 1.7e-59 201.3 0.0 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 ABK74354.1 - 7.2e-36 123.6 0.0 1.1e-35 123.1 0.0 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain p450 PF00067.22 ABK74355.1 - 1.7e-16 60.0 0.1 2.6e-12 46.2 0.0 3.1 3 0 0 3 3 3 3 Cytochrome P450 FAD-oxidase_C PF02913.19 ABK74357.1 - 1.9e-66 224.3 0.7 2.7e-66 223.7 0.7 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 ABK74357.1 - 1.5e-43 147.8 1.4 2.9e-43 146.9 1.4 1.5 1 0 0 1 1 1 1 FAD binding domain Lact-deh-memb PF09330.11 ABK74357.1 - 0.041 13.2 0.0 0.64 9.3 0.0 2.0 2 0 0 2 2 2 0 D-lactate dehydrogenase, membrane binding DUF2339 PF10101.9 ABK74358.1 - 5e-24 84.9 106.2 7.6e-13 47.9 73.7 2.2 1 1 1 2 2 2 2 Predicted membrane protein (DUF2339) Pex14_N PF04695.13 ABK74358.1 - 0.0088 16.7 2.3 0.021 15.5 2.3 1.6 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4212 PF13937.6 ABK74358.1 - 0.19 12.1 2.8 0.48 10.8 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4212) DUF2784 PF10861.8 ABK74359.1 - 1.3e-29 102.5 2.4 1.5e-29 102.3 2.4 1.1 1 0 0 1 1 1 1 Protein of Unknown function (DUF2784) Glycos_trans_3N PF02885.17 ABK74359.1 - 0.094 12.6 0.1 7.1 6.6 0.2 2.4 1 1 1 2 2 2 0 Glycosyl transferase family, helical bundle domain Lycopene_cycl PF05834.12 ABK74360.1 - 1.5e-12 47.3 2.4 3.2e-11 42.9 1.9 2.7 2 1 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.14 ABK74360.1 - 5.6e-12 45.3 2.2 2.5e-06 26.6 0.6 2.3 1 1 0 2 2 2 2 Tryptophan halogenase DAO PF01266.24 ABK74360.1 - 8.8e-06 25.5 4.6 0.032 13.8 0.4 2.7 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ABK74360.1 - 4.5e-05 22.8 0.0 8.8e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ABK74360.1 - 5.6e-05 22.5 1.3 0.00011 21.5 1.3 1.5 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 ABK74360.1 - 0.012 14.8 0.0 0.028 13.7 0.0 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 ABK74360.1 - 0.015 15.5 0.0 0.055 13.7 0.0 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ABK74360.1 - 0.023 13.8 0.2 0.056 12.5 0.2 1.6 1 0 0 1 1 1 0 FAD binding domain PALP PF00291.25 ABK74360.1 - 0.046 13.1 0.0 0.086 12.2 0.0 1.5 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme NAD_binding_7 PF13241.6 ABK74360.1 - 0.058 13.8 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding UPF0227 PF05728.12 ABK74360.1 - 0.17 11.8 0.1 0.42 10.5 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Pyr_redox PF00070.27 ABK74360.1 - 0.17 12.4 0.0 0.56 10.8 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SnoaL_2 PF12680.7 ABK74361.1 - 1.1e-08 35.6 1.0 1.9e-08 34.9 0.4 1.6 1 1 1 2 2 2 1 SnoaL-like domain SnoaL PF07366.12 ABK74361.1 - 0.0025 17.6 0.0 0.0043 16.8 0.0 1.5 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_3 PF13474.6 ABK74361.1 - 0.0042 17.3 0.0 0.0088 16.3 0.0 1.6 2 0 0 2 2 2 1 SnoaL-like domain DUF4440 PF14534.6 ABK74361.1 - 0.0072 16.7 0.2 0.014 15.8 0.1 1.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4440) Pkinase PF00069.25 ABK74362.1 - 4.7e-45 154.0 0.0 6.2e-45 153.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ABK74362.1 - 1.3e-28 100.0 0.0 1.9e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ABK74362.1 - 1e-05 25.6 6.6 0.0043 17.0 0.1 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 ABK74362.1 - 0.0025 17.2 0.0 0.0061 15.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 ABK74362.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 ABK74362.1 - 0.013 14.9 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ABK74362.1 - 0.043 12.8 0.0 0.055 12.4 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 ABK74362.1 - 0.047 12.5 0.0 0.062 12.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase MspA PF09203.11 ABK74363.1 - 5.9e-40 137.0 0.1 7.5e-40 136.6 0.1 1.1 1 0 0 1 1 1 1 MspA ABC_tran PF00005.27 ABK74364.1 - 8.2e-27 94.4 0.0 1.4e-26 93.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK74364.1 - 3e-16 60.1 0.4 4.9e-11 43.0 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ABK74364.1 - 0.0075 16.8 0.1 0.012 16.2 0.1 1.2 1 0 0 1 1 1 1 AAA domain HlyE PF06109.13 ABK74364.1 - 0.017 14.5 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Haemolysin E (HlyE) AAA_22 PF13401.6 ABK74364.1 - 0.026 14.8 0.0 0.28 11.5 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_13 PF13166.6 ABK74364.1 - 0.027 13.2 0.0 2.5 6.6 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 ABK74364.1 - 0.069 13.5 0.1 0.18 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain SMC_N PF02463.19 ABK74364.1 - 0.13 11.7 0.0 12 5.2 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA PF00004.29 ABK74364.1 - 0.28 11.6 1.1 5 7.6 0.3 2.9 2 2 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF3584 PF12128.8 ABK74364.1 - 0.3 8.5 0.3 0.42 8.1 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_30 PF13604.6 ABK74364.1 - 0.66 9.7 3.5 0.42 10.3 0.4 2.3 3 1 0 3 3 3 0 AAA domain IlvN PF07991.12 ABK74365.1 - 1.2e-71 239.7 0.2 1.6e-71 239.2 0.2 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 ABK74365.1 - 2e-62 209.7 0.1 2.7e-62 209.3 0.1 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.19 ABK74365.1 - 1.6e-06 27.6 0.0 2.7e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 ABK74365.1 - 3.3e-05 24.1 0.0 9.3e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ABK74365.1 - 3.9e-05 24.1 0.0 0.00011 22.8 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 ABK74365.1 - 0.0021 18.2 0.0 0.0047 17.0 0.0 1.5 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Exog_C PF18026.1 ABK74365.1 - 0.12 12.5 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 Endo/exonuclease (EXOG) C-terminal domain NAD_binding_7 PF13241.6 ABK74365.1 - 0.15 12.5 0.1 0.47 10.9 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Wzz PF02706.15 ABK74366.1 - 0.0064 16.8 0.8 0.0064 16.8 0.8 2.0 2 0 0 2 2 2 1 Chain length determinant protein REC114-like PF15165.6 ABK74366.1 - 0.047 13.5 0.0 0.054 13.3 0.0 1.2 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like RskA PF10099.9 ABK74366.1 - 0.076 13.3 7.5 0.18 12.1 5.0 2.1 1 1 1 2 2 2 0 Anti-sigma-K factor rskA PEMT PF04191.13 ABK74366.1 - 0.15 12.5 0.7 0.3 11.5 0.7 1.5 1 0 0 1 1 1 0 Phospholipid methyltransferase DUF3040 PF11239.8 ABK74366.1 - 0.15 12.3 6.8 2.6 8.4 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) GP41 PF00517.17 ABK74366.1 - 0.21 11.4 0.2 0.41 10.5 0.2 1.4 1 0 0 1 1 1 0 Retroviral envelope protein UTRA PF07702.13 ABK74367.1 - 2e-41 141.2 0.0 2.6e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 UTRA domain GntR PF00392.21 ABK74367.1 - 7e-12 44.8 0.3 1.5e-11 43.7 0.3 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Rrf2 PF02082.20 ABK74367.1 - 2.6e-08 34.1 0.1 5.2e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulator HTH_20 PF12840.7 ABK74367.1 - 0.00054 20.0 0.3 0.0013 18.7 0.3 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 ABK74367.1 - 0.00058 19.8 0.0 0.0016 18.4 0.0 1.7 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_11 PF08279.12 ABK74367.1 - 0.0013 18.6 0.1 0.0027 17.6 0.1 1.5 1 0 0 1 1 1 1 HTH domain MarR PF01047.22 ABK74367.1 - 0.0014 18.5 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 ABK74367.1 - 0.0015 18.4 0.2 0.0031 17.4 0.2 1.6 1 0 0 1 1 1 1 MarR family HTH_28 PF13518.6 ABK74367.1 - 0.0018 18.4 0.1 0.0047 17.0 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 ABK74367.1 - 0.0029 17.4 0.1 0.0074 16.1 0.1 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain TrmB PF01978.19 ABK74367.1 - 0.0031 17.4 0.0 0.0075 16.1 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB RP-C PF03428.13 ABK74367.1 - 0.0053 16.4 0.1 0.052 13.2 0.1 2.1 2 0 0 2 2 2 1 Replication protein C N-terminal domain HTH_5 PF01022.20 ABK74367.1 - 0.0072 16.2 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 ABK74367.1 - 0.019 14.5 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF4191 PF13829.6 ABK74367.1 - 0.05 13.0 0.0 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) HTH_27 PF13463.6 ABK74367.1 - 0.062 13.8 0.1 0.27 11.8 0.0 2.1 2 0 0 2 2 2 0 Winged helix DNA-binding domain HTH_DeoR PF08220.12 ABK74367.1 - 0.096 12.4 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain TFIIE_alpha PF02002.17 ABK74367.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 TFIIE alpha subunit RepL PF05732.11 ABK74367.1 - 0.2 11.1 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) Acyl-CoA_dh_1 PF00441.24 ABK74368.1 - 5.3e-47 159.8 0.6 8.1e-47 159.2 0.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK74368.1 - 4.4e-27 95.0 0.0 1.6e-26 93.2 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ABK74368.1 - 1.4e-26 92.5 0.0 2.7e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ABK74368.1 - 1.3e-18 67.5 0.3 2.6e-18 66.6 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 ABK74368.1 - 0.16 11.6 0.0 0.32 10.6 0.0 1.4 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal DUF2126 PF09899.9 ABK74369.1 - 0 1173.0 0.0 0 1170.7 0.0 1.8 1 1 0 1 1 1 1 Putative amidoligase enzyme (DUF2126) Bact_transglu_N PF08379.10 ABK74369.1 - 2.7e-26 92.2 0.6 8.3e-26 90.7 0.6 1.9 1 0 0 1 1 1 1 Bacterial transglutaminase-like N-terminal region Transglut_core PF01841.19 ABK74369.1 - 1.8e-20 73.5 0.0 3.6e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily BiPBP_C PF06832.12 ABK74369.1 - 0.1 12.6 2.2 24 5.1 0.5 3.5 4 0 0 4 4 4 0 Penicillin-Binding Protein C-terminus Family CoA_transf_3 PF02515.17 ABK74370.1 - 2.7e-139 464.4 4.3 8.8e-85 285.0 2.0 2.0 2 0 0 2 2 2 2 CoA-transferase family III F420H2_quin_red PF04075.14 ABK74371.1 - 4.3e-05 23.6 0.1 4.7e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase Dicistro_VP4 PF11492.8 ABK74371.1 - 0.014 15.3 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Cricket paralysis virus, VP4 DUF2630 PF10944.8 ABK74372.1 - 1.1e-33 115.5 10.5 1.2e-33 115.4 10.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2630) CHASE3 PF05227.13 ABK74372.1 - 0.011 15.7 4.4 0.011 15.6 4.4 1.0 1 0 0 1 1 1 0 CHASE3 domain DUF1974 PF09317.11 ABK74372.1 - 0.042 13.4 0.5 0.041 13.5 0.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) COX16 PF14138.6 ABK74372.1 - 0.12 12.8 1.3 0.14 12.6 1.3 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 SpecificRecomb PF10136.9 ABK74372.1 - 0.13 10.5 1.0 0.16 10.3 1.0 1.0 1 0 0 1 1 1 0 Site-specific recombinase TPP_enzyme_N PF02776.18 ABK74373.1 - 1.9e-47 161.0 0.5 1.9e-47 161.0 0.5 3.1 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 ABK74373.1 - 5.5e-33 113.6 1.5 5.5e-32 110.4 0.6 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 ABK74373.1 - 2e-28 99.1 0.9 1.4e-27 96.4 0.3 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M_2 PF16582.5 ABK74373.1 - 0.022 14.5 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 Middle domain of thiamine pyrophosphate Asparaginase PF00710.20 ABK74374.1 - 2e-47 161.2 0.3 3.2e-47 160.6 0.3 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 ABK74374.1 - 9.5e-24 83.8 0.1 3e-23 82.2 0.1 1.9 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain F420H2_quin_red PF04075.14 ABK74375.1 - 1.4e-44 151.4 0.0 1.6e-44 151.2 0.0 1.0 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase ECH_1 PF00378.20 ABK74376.1 - 9.6e-20 70.9 0.0 3.1e-10 39.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK74376.1 - 1.9e-06 27.6 0.0 0.00022 20.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 ABK74377.1 - 5.6e-39 134.0 0.0 6.1e-39 133.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK74377.1 - 2.8e-26 92.8 0.0 3.4e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase TetR_N PF00440.23 ABK74378.1 - 7.7e-11 41.6 1.0 1.8e-10 40.4 1.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 ABK74378.1 - 0.00012 22.3 0.1 0.00022 21.5 0.1 1.5 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_15 PF17918.1 ABK74378.1 - 0.00029 21.5 0.3 0.00029 21.5 0.3 2.1 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain HTH_IclR PF09339.10 ABK74378.1 - 0.015 15.1 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain DUF4136 PF13590.6 ABK74378.1 - 0.039 14.5 0.0 0.058 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4136) LacI PF00356.21 ABK74378.1 - 0.17 11.7 0.2 2.5 8.0 0.0 2.6 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family Abhydrolase_1 PF00561.20 ABK74379.1 - 4.4e-13 49.5 0.0 6.1e-10 39.2 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK74379.1 - 1.3e-10 42.2 3.2 1.8e-10 41.8 3.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK74379.1 - 3.4e-07 29.8 0.0 5.1e-05 22.7 0.0 2.0 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 ABK74379.1 - 0.0015 18.4 0.0 0.0023 17.8 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.20 ABK74379.1 - 0.0018 18.0 0.0 0.0022 17.7 0.0 1.2 1 0 0 1 1 1 1 Putative esterase CobA_CobO_BtuR PF02572.15 ABK74380.1 - 1.4e-60 204.5 0.0 1.6e-60 204.3 0.0 1.0 1 0 0 1 1 1 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP TPP_enzyme_N PF02776.18 ABK74380.1 - 0.33 10.5 1.1 27 4.3 0.2 2.8 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain adh_short_C2 PF13561.6 ABK74381.1 - 5.6e-68 229.0 11.4 6.3e-68 228.8 11.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK74381.1 - 2.5e-57 193.5 4.6 3e-57 193.3 4.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK74381.1 - 2.1e-10 40.8 5.7 3.3e-10 40.2 5.7 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK74381.1 - 0.00051 19.6 1.4 0.00061 19.3 0.8 1.4 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family IclR PF01614.18 ABK74382.1 - 5.1e-18 65.2 0.0 1e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 ABK74382.1 - 2e-10 40.3 2.7 4.5e-10 39.2 2.7 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_5 PF01022.20 ABK74383.1 - 2.6e-14 52.8 0.2 4.8e-14 52.0 0.2 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 ABK74383.1 - 4.3e-11 42.7 1.0 8.7e-11 41.7 1.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 ABK74383.1 - 1e-05 25.3 0.5 1.6e-05 24.7 0.5 1.4 1 0 0 1 1 1 1 MarR family MarR PF01047.22 ABK74383.1 - 0.00014 21.7 0.0 0.00024 20.9 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 ABK74383.1 - 0.00037 20.4 0.2 0.00053 19.9 0.2 1.2 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_IclR PF09339.10 ABK74383.1 - 0.0024 17.6 0.9 0.0048 16.7 0.9 1.6 1 1 0 1 1 1 1 IclR helix-turn-helix domain TrmB PF01978.19 ABK74383.1 - 0.0033 17.3 0.0 0.0062 16.4 0.0 1.4 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 ABK74383.1 - 0.0042 16.6 0.1 0.0063 16.0 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_27 PF13463.6 ABK74383.1 - 0.0068 16.9 0.0 0.011 16.3 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain Rrf2 PF02082.20 ABK74383.1 - 0.012 15.9 0.1 0.015 15.6 0.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator HrcA_DNA-bdg PF03444.15 ABK74383.1 - 0.016 14.8 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding DprA_WH PF17782.1 ABK74383.1 - 0.03 14.4 1.9 0.055 13.6 1.9 1.5 1 1 0 1 1 1 0 DprA winged helix domain HTH_1 PF00126.27 ABK74383.1 - 0.033 14.1 0.0 0.075 13.0 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family PaaX PF07848.12 ABK74383.1 - 0.061 13.6 0.0 0.096 12.9 0.0 1.3 1 0 0 1 1 1 0 PaaX-like protein Amidinotransf PF02274.17 ABK74386.1 - 6.6e-18 64.9 0.0 8.6e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Amidinotransferase ABC_tran PF00005.27 ABK74387.1 - 3.3e-22 79.5 0.0 5.8e-14 52.8 0.0 3.9 3 1 0 3 3 3 3 ABC transporter SMC_N PF02463.19 ABK74387.1 - 6.7e-10 38.8 0.1 0.065 12.7 0.0 4.1 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ABK74387.1 - 7e-09 35.3 0.2 0.0031 17.2 0.1 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain DnaJ_CXXCXGXG PF00684.19 ABK74387.1 - 2.6e-07 30.9 3.6 0.0012 19.2 0.4 3.3 3 0 0 3 3 3 1 DnaJ central domain AAA_16 PF13191.6 ABK74387.1 - 9.2e-07 29.4 0.1 0.13 12.6 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 ABK74387.1 - 2e-06 27.9 7.1 0.21 11.4 0.0 4.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system Anti-TRAP PF15777.5 ABK74387.1 - 5.1e-06 26.4 2.8 0.038 13.9 0.4 3.6 3 0 0 3 3 3 1 Tryptophan RNA-binding attenuator protein inhibitory protein RsgA_GTPase PF03193.16 ABK74387.1 - 2.5e-05 24.2 0.1 0.0093 15.9 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 ABK74387.1 - 4.5e-05 23.6 0.0 0.23 11.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 ABK74387.1 - 0.00013 22.5 0.2 0.27 11.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain UvrA_DNA-bind PF17755.1 ABK74387.1 - 0.00014 22.1 0.0 0.00038 20.8 0.0 1.7 1 0 0 1 1 1 1 UvrA DNA-binding domain AAA_15 PF13175.6 ABK74387.1 - 0.00086 19.1 0.5 5.9 6.5 0.1 3.9 4 0 0 4 4 4 1 AAA ATPase domain Viral_helicase1 PF01443.18 ABK74387.1 - 0.00099 18.9 0.2 0.33 10.6 0.2 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 ABK74387.1 - 0.0051 16.6 2.3 2.7 7.7 0.3 3.4 3 0 0 3 3 3 1 AAA domain cobW PF02492.19 ABK74387.1 - 0.0065 16.1 0.9 3.5 7.2 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 ABK74387.1 - 0.0079 15.8 0.3 5.9 6.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain RNA12 PF10443.9 ABK74387.1 - 0.011 14.5 0.1 0.68 8.6 0.0 2.2 2 0 0 2 2 2 0 RNA12 protein AAA_22 PF13401.6 ABK74387.1 - 0.018 15.3 0.3 20 5.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 ABK74387.1 - 0.026 14.4 0.2 4.3 7.2 0.2 2.5 2 0 0 2 2 2 0 NACHT domain zinc_ribbon_9 PF14369.6 ABK74387.1 - 0.039 14.2 2.7 11 6.4 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon AAA_18 PF13238.6 ABK74387.1 - 0.079 13.5 3.0 12 6.4 0.7 3.5 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.9 ABK74387.1 - 0.087 12.1 0.8 6.8 5.8 0.8 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 ABK74387.1 - 0.091 12.1 0.1 35 3.6 0.0 3.3 3 0 0 3 3 3 0 KaiC AAA_28 PF13521.6 ABK74387.1 - 0.18 12.0 0.3 15 5.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 ABK74387.1 - 0.25 11.2 0.0 15 5.4 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea zf-TFIIB PF13453.6 ABK74387.1 - 7.8 5.9 7.8 18 4.8 0.0 3.6 3 1 0 3 3 3 0 Transcription factor zinc-finger ADH_zinc_N PF00107.26 ABK74388.1 - 1.6e-14 54.0 2.5 3.1e-14 53.1 0.6 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ABK74388.1 - 3.1e-14 54.2 0.1 6e-14 53.2 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ABK74388.1 - 1.6e-08 34.4 0.0 5.7e-08 32.6 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 ABK74388.1 - 2.6e-05 23.8 0.1 4.6e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 ABK74388.1 - 0.0029 17.2 0.4 0.0042 16.7 0.4 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ABK74388.1 - 0.012 15.5 0.4 0.024 14.5 0.4 1.5 1 0 0 1 1 1 0 NAD(P)H-binding DapB_N PF01113.20 ABK74388.1 - 0.013 15.6 1.2 0.024 14.7 0.7 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.17 ABK74388.1 - 0.097 11.8 0.1 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain MeaB PF03308.16 ABK74390.1 - 9.3e-74 247.8 5.5 1.9e-73 246.8 5.5 1.4 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 ABK74390.1 - 8.7e-08 32.0 1.1 7.5e-07 28.9 0.7 2.4 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 ABK74390.1 - 1.7e-05 24.7 0.4 1.7e-05 24.7 0.4 2.0 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 ABK74390.1 - 3.3e-05 24.0 0.0 7.2e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.17 ABK74390.1 - 7e-05 22.7 0.1 0.0003 20.7 0.1 1.9 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 ABK74390.1 - 0.0042 17.0 0.1 0.014 15.3 0.1 1.8 2 0 0 2 2 2 1 NTPase FeoB_N PF02421.18 ABK74390.1 - 0.0049 16.4 0.5 0.13 11.8 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B SRP54 PF00448.22 ABK74390.1 - 0.0056 16.3 0.2 0.014 15.0 0.2 2.0 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 ABK74390.1 - 0.014 15.7 4.1 0.069 13.5 4.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 ABK74390.1 - 0.015 15.8 0.1 0.045 14.3 0.0 1.7 2 0 0 2 2 2 0 ABC transporter GTP_EFTU PF00009.27 ABK74390.1 - 0.017 14.7 0.1 9.3 5.7 0.0 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Fer4_NifH PF00142.18 ABK74390.1 - 0.024 14.1 0.1 0.19 11.1 0.0 2.0 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_22 PF13401.6 ABK74390.1 - 0.026 14.8 0.1 0.12 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF1611 PF07755.11 ABK74390.1 - 0.029 13.6 0.2 2 7.7 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1611_C) P-loop domain AAA_19 PF13245.6 ABK74390.1 - 0.04 14.2 0.9 0.09 13.1 0.2 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 ABK74390.1 - 0.052 14.1 0.3 0.16 12.5 0.1 1.9 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 ABK74390.1 - 0.071 12.3 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 ABK74390.1 - 0.11 12.6 0.2 0.57 10.3 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase PRK PF00485.18 ABK74390.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.6 ABK74390.1 - 0.13 12.0 0.1 0.27 11.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.14 ABK74390.1 - 0.14 12.1 0.0 0.43 10.5 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DDE_Tnp_ISL3 PF01610.17 ABK74391.1 - 1.6e-64 217.9 0.0 2.1e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Transposase zf-ISL3 PF14690.6 ABK74391.1 - 1.1e-09 38.8 4.6 1.8e-09 38.1 2.5 2.5 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HTH_Tnp_ISL3 PF13542.6 ABK74391.1 - 2.4e-08 33.2 1.6 7e-08 31.8 1.6 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 ABC_tran PF00005.27 ABK74392.1 - 5e-27 95.1 0.0 2.7e-26 92.7 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK74392.1 - 2.3e-05 24.3 0.0 0.0015 18.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ABK74392.1 - 7.8e-05 23.0 0.0 0.00027 21.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ABK74392.1 - 0.00013 22.4 1.2 0.00016 22.1 1.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 ABK74392.1 - 0.00031 20.4 0.0 0.00063 19.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 ABK74392.1 - 0.00076 19.7 0.1 0.0079 16.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ABK74392.1 - 0.0026 17.7 0.1 0.0043 17.0 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 ABK74392.1 - 0.0052 16.5 0.4 0.021 14.6 0.1 2.0 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 ABK74392.1 - 0.0054 17.0 0.3 0.82 9.9 0.1 2.4 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 ABK74392.1 - 0.035 14.2 0.0 0.071 13.2 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_ATPase PF09818.9 ABK74392.1 - 0.049 12.4 0.6 5.1 5.8 0.0 2.8 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_25 PF13481.6 ABK74392.1 - 0.054 13.1 0.8 0.099 12.2 0.7 1.8 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 ABK74392.1 - 0.066 12.2 0.1 0.096 11.7 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_15 PF13175.6 ABK74392.1 - 0.18 11.5 0.0 0.24 11.1 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 ABK74392.1 - 0.19 11.6 1.2 0.44 10.4 0.9 1.9 1 1 0 1 1 1 0 NACHT domain SbcCD_C PF13558.6 ABK74392.1 - 0.2 11.9 1.2 0.7 10.2 0.4 2.3 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 ABK74392.1 - 0.21 12.1 0.0 0.25 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain Pro_CA PF00484.19 ABK74393.1 - 1.5e-13 51.3 0.1 4.6e-12 46.5 0.1 2.0 1 1 0 1 1 1 1 Carbonic anhydrase zf-IS66 PF13005.7 ABK74393.1 - 0.038 14.4 0.0 0.085 13.3 0.0 1.6 1 0 0 1 1 1 0 zinc-finger binding domain of transposase IS66 Band_7 PF01145.25 ABK74394.1 - 6.4e-33 114.3 3.1 8.5e-33 113.8 3.1 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 ABK74394.1 - 0.0011 18.7 0.0 0.0021 17.8 0.0 1.5 1 1 0 1 1 1 1 SPFH domain-Band 7 family DUF4228 PF14009.6 ABK74394.1 - 0.05 14.0 0.0 0.078 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) TetR_N PF00440.23 ABK74395.1 - 6.8e-17 61.0 0.0 1.3e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_10 PF04967.12 ABK74395.1 - 6.3e-05 22.7 0.1 0.00047 19.9 0.0 2.3 2 0 0 2 2 2 1 HTH DNA binding domain HTH_20 PF12840.7 ABK74395.1 - 0.012 15.7 0.0 0.041 13.9 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_24 PF13412.6 ABK74395.1 - 0.024 14.2 0.0 0.082 12.5 0.0 2.0 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 ABK74395.1 - 0.035 13.9 0.4 1.7 8.5 0.0 2.9 3 1 0 3 3 3 0 IclR helix-turn-helix domain HTH_5 PF01022.20 ABK74395.1 - 0.041 13.7 0.0 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_Tnp_1_2 PF13022.6 ABK74395.1 - 0.063 13.4 0.0 0.09 12.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_22 PF13309.6 ABK74395.1 - 0.099 12.7 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 HTH domain Aldedh PF00171.22 ABK74396.1 - 2.9e-164 547.0 0.1 3.3e-164 546.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Intg_mem_TP0381 PF09529.10 ABK74397.1 - 4.4e-58 196.4 12.0 5.3e-58 196.2 12.0 1.0 1 0 0 1 1 1 1 Integral membrane protein (intg_mem_TP0381) Glucos_trans_II PF14264.6 ABK74397.1 - 0.00028 20.3 4.3 0.013 14.9 0.8 2.2 2 0 0 2 2 2 2 Glucosyl transferase GtrII EamA PF00892.20 ABK74397.1 - 0.048 13.8 0.5 0.048 13.8 0.5 2.9 2 1 1 3 3 3 0 EamA-like transporter family Cytochrom_B_C PF00032.17 ABK74397.1 - 0.11 12.8 0.1 0.11 12.8 0.1 3.3 3 1 1 4 4 4 0 Cytochrome b(C-terminal)/b6/petD BioY PF02632.14 ABK74397.1 - 0.11 12.5 12.6 0.034 14.2 2.5 2.3 2 1 0 2 2 2 0 BioY family DUF3810 PF12725.7 ABK74397.1 - 9.3 5.5 13.2 10 5.4 4.7 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3810) VKOR PF07884.14 ABK74399.1 - 6.1e-32 110.4 13.4 6.1e-32 110.4 13.4 1.8 2 0 0 2 2 2 1 Vitamin K epoxide reductase family FTR1 PF03239.14 ABK74399.1 - 9 5.4 13.8 0.13 11.4 6.2 1.9 2 1 0 2 2 2 0 Iron permease FTR1 family FAA_hydrolase PF01557.18 ABK74401.1 - 1.2e-65 221.2 0.0 1.4e-65 221.0 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2437 PF10370.9 ABK74401.1 - 3.6e-15 56.6 0.2 1.7e-14 54.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF2437) AMP-binding PF00501.28 ABK74402.1 - 9.5e-68 228.7 0.0 1.3e-67 228.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK74402.1 - 1.4e-17 64.4 0.3 3.6e-17 63.1 0.3 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain P5CR_dimer PF14748.6 ABK74403.1 - 5.4e-41 139.0 8.2 5.4e-41 139.0 8.2 2.1 2 1 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 ABK74403.1 - 1.3e-22 80.1 2.0 3.1e-22 79.0 2.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 ABK74403.1 - 1.4e-06 28.6 0.7 1.4e-06 28.6 0.7 2.3 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 ABK74403.1 - 5.9e-06 26.4 0.4 1e-05 25.6 0.4 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 ABK74403.1 - 0.00013 21.5 1.0 0.00024 20.7 1.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 ABK74403.1 - 0.00018 21.2 1.4 0.00051 19.7 1.4 1.8 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Rossmann-like PF10727.9 ABK74403.1 - 0.00032 20.6 1.9 0.00088 19.1 1.9 1.7 1 0 0 1 1 1 1 Rossmann-like domain NAD_binding_7 PF13241.6 ABK74403.1 - 0.00039 20.8 0.9 0.00039 20.8 0.9 1.9 2 0 0 2 2 2 1 Putative NAD(P)-binding GFO_IDH_MocA PF01408.22 ABK74403.1 - 0.00046 21.0 0.5 0.0012 19.7 0.2 2.0 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.18 ABK74403.1 - 0.001 19.3 0.2 0.0036 17.5 0.2 2.0 1 1 0 1 1 1 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 ABK74403.1 - 0.0026 18.0 0.3 0.0054 17.0 0.3 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 ABK74403.1 - 0.02 14.7 0.7 0.055 13.4 0.6 1.8 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 ABK74403.1 - 0.037 14.0 1.8 0.24 11.4 1.8 2.1 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Methyltransf_14 PF08484.11 ABK74404.1 - 2.4e-62 209.5 0.0 4e-62 208.7 0.0 1.4 1 0 0 1 1 1 1 C-methyltransferase C-terminal domain Methyltransf_13 PF08421.11 ABK74404.1 - 7.8e-22 77.3 1.6 1.4e-21 76.5 1.6 1.4 1 0 0 1 1 1 1 Putative zinc binding domain Methyltransf_23 PF13489.6 ABK74404.1 - 1.3e-14 54.4 0.0 3.2e-14 53.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK74404.1 - 2.7e-06 28.1 0.0 5.3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABK74404.1 - 0.00054 20.5 0.0 0.0012 19.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABK74404.1 - 0.041 14.6 0.2 0.094 13.4 0.1 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 ABK74404.1 - 0.06 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.25 ABK74405.1 - 3.5e-47 160.4 0.2 4.2e-47 160.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK74405.1 - 2.9e-39 135.0 2.4 3.4e-39 134.8 2.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK74405.1 - 2.4e-12 47.2 0.4 3.3e-12 46.7 0.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK74405.1 - 5.4e-08 32.6 0.7 8.1e-08 32.0 0.7 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DEAD PF00270.29 ABK74405.1 - 9.2e-05 22.3 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase GDP_Man_Dehyd PF16363.5 ABK74405.1 - 0.0017 17.8 0.1 0.0024 17.3 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase ApbA PF02558.16 ABK74405.1 - 0.0036 17.0 0.6 0.0073 16.0 0.6 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Acyl-CoA_dh_N PF02771.16 ABK74406.1 - 2e-09 38.1 0.0 8.1e-09 36.1 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ABK74406.1 - 9.5e-08 32.4 0.0 1.7e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.24 ABK74406.1 - 1.9e-05 24.9 0.1 7.4e-05 23.0 0.1 1.9 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK74406.1 - 2.7e-05 24.3 0.1 9.3e-05 22.6 0.1 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Mycobact_memb PF05423.13 ABK74407.1 - 4.4e-08 33.1 0.9 1e-07 32.0 0.1 1.8 2 0 0 2 2 2 1 Mycobacterium membrane protein Transket_pyr PF02779.24 ABK74408.1 - 2.8e-39 134.6 0.0 5.1e-39 133.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ABK74408.1 - 3.2e-38 130.4 0.0 2.1e-37 127.8 0.0 2.0 2 0 0 2 2 2 1 Transketolase, C-terminal domain BPD_transp_1 PF00528.22 ABK74409.1 - 6.6e-30 104.2 12.8 6.6e-30 104.2 12.8 1.8 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component PEP-utilizers_C PF02896.18 ABK74411.1 - 3.5e-80 269.3 0.0 5e-80 268.8 0.0 1.1 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilisers_N PF05524.13 ABK74411.1 - 7.1e-28 97.1 0.5 3.9e-27 94.7 0.5 2.4 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal EIIA-man PF03610.16 ABK74411.1 - 7.1e-24 84.3 1.3 1.8e-23 83.0 1.3 1.8 1 0 0 1 1 1 1 PTS system fructose IIA component PTS-HPr PF00381.19 ABK74411.1 - 5.7e-18 64.9 0.0 2.5e-17 62.9 0.0 2.2 2 0 0 2 2 2 1 PTS HPr component phosphorylation site PEP-utilizers PF00391.23 ABK74411.1 - 1.3e-10 40.8 1.9 3.7e-10 39.4 1.9 1.8 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain DUF543 PF04418.12 ABK74411.1 - 2.2 8.3 6.7 22 5.1 0.4 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF543) ArsP_1 PF03773.13 ABK74412.1 - 1.1 8.4 6.2 0.75 8.9 3.7 1.7 1 1 1 2 2 2 0 Predicted permease LtrA PF06772.11 ABK74413.1 - 2e-90 303.6 53.1 2.3e-90 303.3 53.1 1.0 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) PsbM PF05151.12 ABK74413.1 - 0.058 13.2 1.9 0.25 11.2 1.9 2.1 1 0 0 1 1 1 0 Photosystem II reaction centre M protein (PsbM) SKG6 PF08693.10 ABK74413.1 - 3.2 7.2 10.2 2.4 7.6 3.6 3.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Pyr_redox_3 PF13738.6 ABK74414.1 - 2e-18 66.7 0.0 9.8e-17 61.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ABK74414.1 - 2.2e-13 50.1 0.0 7.9e-12 45.0 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 ABK74414.1 - 6.7e-13 48.5 0.0 5.7e-11 42.2 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ABK74414.1 - 7.5e-07 28.7 1.5 0.00012 21.4 0.2 2.6 3 0 0 3 3 3 2 FAD binding domain HI0933_like PF03486.14 ABK74414.1 - 1.8e-06 27.0 1.3 0.0032 16.2 0.0 3.0 3 0 0 3 3 3 2 HI0933-like protein FMO-like PF00743.19 ABK74414.1 - 1.2e-05 24.0 0.0 3.9e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like DAO PF01266.24 ABK74414.1 - 1.3e-05 25.0 0.3 0.0003 20.5 0.1 3.1 3 1 1 4 4 4 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ABK74414.1 - 0.00022 21.4 2.0 0.062 13.5 0.0 3.4 4 0 0 4 4 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ABK74414.1 - 0.00034 19.8 0.9 0.2 10.7 0.0 3.2 3 1 0 3 3 3 1 FAD binding domain Pyr_redox PF00070.27 ABK74414.1 - 0.0014 19.1 0.3 3 8.5 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 ABK74414.1 - 0.0087 16.1 0.0 3.5 7.7 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 ABK74414.1 - 0.013 15.5 7.0 0.44 10.5 0.1 3.2 2 1 1 3 3 3 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 ABK74414.1 - 0.016 15.1 1.0 4.4 7.1 0.3 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 ABK74414.1 - 0.03 13.7 1.3 3.1 7.1 0.2 2.2 2 0 0 2 2 2 0 ThiF family ApbA PF02558.16 ABK74414.1 - 0.04 13.6 1.3 1.5 8.5 0.2 2.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 ABK74414.1 - 0.049 12.9 0.2 0.19 10.9 0.0 1.8 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.18 ABK74414.1 - 0.052 13.8 0.2 14 6.0 0.0 2.6 2 0 0 2 2 2 0 TrkA-N domain GIDA PF01134.22 ABK74414.1 - 0.053 12.6 0.1 0.053 12.6 0.1 2.4 3 0 0 3 3 3 0 Glucose inhibited division protein A F420_oxidored PF03807.17 ABK74414.1 - 0.06 13.9 0.2 5.7 7.6 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Lycopene_cycl PF05834.12 ABK74414.1 - 0.084 11.9 1.0 0.79 8.7 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein GCS2 PF04107.13 ABK74415.1 - 1.4e-73 247.8 0.2 1.8e-73 247.5 0.2 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) FGGY_N PF00370.21 ABK74417.1 - 4.1e-35 121.5 0.0 5.5e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 ABK74417.1 - 1.2e-32 113.2 0.0 2.3e-32 112.3 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Lycopene_cycl PF05834.12 ABK74417.1 - 0.13 11.3 0.7 0.19 10.7 0.1 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein DDE_Tnp_1 PF01609.21 ABK74418.1 - 1.9e-13 50.5 0.0 6.9e-13 48.7 0.0 1.8 1 1 0 1 1 1 1 Transposase DDE domain zf-HC2 PF13490.6 ABK74419.1 - 1.5e-07 31.6 0.6 2.9e-07 30.6 0.6 1.6 1 0 0 1 1 1 1 Putative zinc-finger RskA PF10099.9 ABK74419.1 - 0.21 11.9 9.8 1.5 9.1 9.8 2.0 1 1 0 1 1 1 0 Anti-sigma-K factor rskA ABC_cobalt PF09819.9 ABK74420.1 - 3.1e-38 130.6 15.9 3.1e-38 130.6 15.9 2.0 1 1 1 2 2 2 1 ABC-type cobalt transport system, permease component IncD PF17628.2 ABK74420.1 - 4.4 7.1 18.9 0.44 10.3 4.5 2.4 1 1 0 2 2 2 0 Inclusion membrane protein D FAA_hydrolase PF01557.18 ABK74421.1 - 8e-62 208.7 0.0 9.8e-62 208.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2437 PF10370.9 ABK74421.1 - 0.013 16.4 0.4 0.031 15.2 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2437) HTH_26 PF13443.6 ABK74421.1 - 0.12 12.8 0.0 0.21 12.1 0.0 1.3 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain rve PF00665.26 ABK74422.1 - 6.9e-19 68.2 0.1 1.9e-18 66.8 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 ABK74422.1 - 9.6e-15 54.1 0.5 1.8e-14 53.2 0.5 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 ABK74422.1 - 1.1e-06 29.0 0.0 1.6e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 DDE domain HTH_32 PF13565.6 ABK74422.1 - 0.003 18.1 4.0 0.0042 17.7 0.0 2.7 3 0 0 3 3 3 1 Homeodomain-like domain rve_2 PF13333.6 ABK74422.1 - 0.0034 17.5 0.0 0.0083 16.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DUF4459 PF14673.6 ABK74422.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4459) Hydrolase_4 PF12146.8 ABK74423.1 - 1.6e-83 279.7 1.0 1.8e-83 279.5 1.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ABK74423.1 - 4.2e-16 59.4 0.9 1.7e-12 47.6 1.2 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK74423.1 - 8.6e-14 52.7 11.6 1.1e-13 52.3 11.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ABK74423.1 - 9.6e-06 25.2 0.6 0.00052 19.6 0.0 2.3 2 1 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 ABK74423.1 - 0.00019 21.1 0.0 0.0033 17.0 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Esterase PF00756.20 ABK74423.1 - 0.00023 20.9 0.1 0.00036 20.3 0.1 1.4 1 0 0 1 1 1 1 Putative esterase AXE1 PF05448.12 ABK74423.1 - 0.0042 15.8 1.7 0.0098 14.6 0.2 2.0 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 ABK74423.1 - 0.0047 16.8 0.0 0.23 11.3 0.0 2.7 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 ABK74423.1 - 0.0067 16.1 0.1 0.16 11.5 0.3 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.13 ABK74423.1 - 0.17 11.5 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Alpha-amylase PF00128.24 ABK74424.1 - 4.9e-79 266.3 0.0 7.2e-79 265.8 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF2235 PF09994.9 ABK74425.1 - 3.8e-23 82.3 0.0 7.2e-22 78.1 0.0 2.7 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) SIS_2 PF13580.6 ABK74425.1 - 0.026 14.6 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 SIS domain 4HBT_3 PF13622.6 ABK74426.1 - 4.6e-43 148.3 1.4 5.2e-43 148.1 1.4 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF5628 PF18621.1 ABK74427.1 - 2.7e-57 192.0 0.1 4.5e-57 191.3 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5628) DUF5593 PF18007.1 ABK74427.1 - 4.4e-34 117.1 0.3 8.1e-34 116.2 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5593) PAS_3 PF08447.12 ABK74427.1 - 0.18 12.1 0.0 0.35 11.2 0.0 1.4 1 0 0 1 1 1 0 PAS fold Trp_oprn_chp PF09534.10 ABK74428.1 - 0.002 17.9 0.1 0.0029 17.4 0.1 1.3 1 1 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TRP PF06011.12 ABK74428.1 - 0.0047 15.7 0.0 0.0048 15.7 0.0 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel ABC2_membrane PF01061.24 ABK74428.1 - 0.01 15.3 1.0 0.012 15.0 1.0 1.1 1 0 0 1 1 1 0 ABC-2 type transporter Cyt_c_ox_IV PF12270.8 ABK74428.1 - 0.019 15.1 0.0 0.02 15.0 0.0 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV DUF4131 PF13567.6 ABK74428.1 - 0.031 13.9 0.5 0.04 13.6 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) SLATT_4 PF18186.1 ABK74428.1 - 0.057 13.1 0.0 0.063 12.9 0.0 1.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 TMEM100 PF16311.5 ABK74428.1 - 0.088 12.4 0.3 0.1 12.2 0.3 1.1 1 0 0 1 1 1 0 Transmembrane protein 100 DUF2721 PF11026.8 ABK74428.1 - 0.13 12.2 2.4 0.17 11.7 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF4407 PF14362.6 ABK74428.1 - 0.14 11.5 0.7 0.18 11.2 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Zn-ribbon_8 PF09723.10 ABK74429.1 - 1.1e-15 57.4 0.6 1.6e-15 56.9 0.6 1.3 1 0 0 1 1 1 1 Zinc ribbon domain DHHW PF14286.6 ABK74429.1 - 0.053 12.8 0.6 0.052 12.9 0.6 1.0 1 0 0 1 1 1 0 DHHW protein TFIIS_C PF01096.18 ABK74429.1 - 0.056 13.3 2.6 1.2 9.1 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zinc_ribbon_9 PF14369.6 ABK74429.1 - 0.065 13.5 2.6 0.23 11.7 2.6 1.9 1 1 0 1 1 1 0 zinc-ribbon HypA PF01155.19 ABK74429.1 - 0.077 13.0 0.2 0.11 12.6 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 ABK74429.1 - 0.09 12.8 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein Zn_ribbon_SprT PF17283.2 ABK74429.1 - 0.65 10.0 4.9 1.1 9.2 0.3 2.1 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Apt1 PF10351.9 ABK74429.1 - 1.9 7.3 10.8 1.9 7.3 10.8 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain MFS_1 PF07690.16 ABK74430.1 - 1.1e-24 87.1 44.1 1.1e-24 87.1 44.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.13 ABK74430.1 - 3.2e-23 81.9 35.1 4.3e-23 81.5 35.1 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector 3-alpha PF03475.14 ABK74431.1 - 0.12 12.3 0.2 1.1 9.2 0.1 2.2 2 0 0 2 2 2 0 3-alpha domain DUF222 PF02720.17 ABK74432.1 - 3.3e-44 151.6 9.4 9.5e-38 130.4 7.9 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF222) PRCC PF10253.9 ABK74432.1 - 1.6 9.5 6.2 3.6 8.3 6.2 1.6 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SnoaL_4 PF13577.6 ABK74433.1 - 9.4e-24 84.0 0.2 1.2e-23 83.6 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 ABK74433.1 - 9.6e-06 26.2 0.6 1.3e-05 25.7 0.6 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 ABK74433.1 - 0.00039 20.8 0.6 0.0057 17.0 0.6 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) DUF4350 PF14258.6 ABK74434.1 - 7.8e-10 39.1 1.6 1.4e-09 38.3 0.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4350) MS_channel PF00924.18 ABK74435.1 - 9.1e-23 80.9 0.2 9.1e-23 80.9 0.2 1.5 2 0 0 2 2 2 1 Mechanosensitive ion channel DUF4134 PF13572.6 ABK74435.1 - 0.013 15.7 2.0 0.013 15.7 2.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4134) Claudin_2 PF13903.6 ABK74435.1 - 3.5 7.3 7.7 4.6 6.9 1.1 2.3 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Abhydrolase_1 PF00561.20 ABK74436.1 - 1.4e-24 87.2 0.1 2.5e-24 86.3 0.1 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK74436.1 - 4.8e-21 76.4 5.7 5.9e-21 76.1 5.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK74436.1 - 2.1e-05 23.9 0.2 7.6e-05 22.1 0.1 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 ABK74436.1 - 3.5e-05 22.7 0.0 0.0006 18.6 0.0 2.0 1 1 0 1 1 1 1 Ndr family EHN PF06441.12 ABK74436.1 - 0.011 16.1 0.3 0.033 14.6 0.1 1.9 2 0 0 2 2 2 0 Epoxide hydrolase N terminus Lipase_3 PF01764.25 ABK74436.1 - 0.078 12.8 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) Cupin_5 PF06172.11 ABK74438.1 - 8.4e-49 165.4 0.0 9.3e-49 165.2 0.0 1.0 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Bac_transf PF02397.16 ABK74440.1 - 1.3e-64 217.2 0.0 1.9e-64 216.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial sugar transferase CoA_binding_3 PF13727.6 ABK74440.1 - 9.9e-07 28.9 0.4 9.9e-07 28.9 0.4 1.9 1 1 1 2 2 2 1 CoA-binding domain Acyl-CoA_dh_1 PF00441.24 ABK74441.1 - 2.6e-24 86.1 5.4 2.6e-24 86.1 5.4 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK74441.1 - 3.3e-10 40.6 0.3 9.7e-10 39.1 0.1 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ABK74441.1 - 3.5e-10 40.3 6.9 2.1e-09 37.7 6.9 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Polyketide_cyc2 PF10604.9 ABK74442.1 - 0.00011 22.5 0.1 0.00014 22.2 0.1 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport 6PGD PF00393.19 ABK74443.1 - 3e-122 407.5 0.0 4e-122 407.1 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 ABK74443.1 - 5.7e-49 166.3 0.1 9.2e-49 165.6 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ABK74443.1 - 0.00053 20.5 1.5 0.00086 19.8 0.3 2.0 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 ABK74443.1 - 0.00063 19.4 0.1 0.001 18.7 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 ABK74443.1 - 0.00072 19.5 0.2 0.0014 18.6 0.2 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 ABK74443.1 - 0.006 16.6 0.1 0.015 15.3 0.1 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 ABK74443.1 - 0.014 14.8 0.1 0.026 13.9 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_11 PF14833.6 ABK74443.1 - 0.11 12.7 0.0 0.74 10.1 0.0 2.3 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Nitroreductase PF00881.24 ABK74444.1 - 7.9e-23 81.4 0.0 1.1e-22 80.9 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 ABK74444.1 - 0.00029 20.5 0.0 0.0072 15.9 0.0 2.0 2 0 0 2 2 2 1 Putative TM nitroreductase AAT PF03417.16 ABK74445.1 - 3.1e-16 59.8 0.0 3.7e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Ribosomal_L2_C PF03947.18 ABK74446.1 - 2.5e-55 186.0 3.8 5e-55 185.1 3.8 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 ABK74446.1 - 3.9e-34 116.5 1.9 8e-34 115.5 1.9 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Fer4_11 PF13247.6 ABK74447.1 - 2.7e-23 82.0 6.8 4.8e-23 81.2 6.8 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 ABK74447.1 - 2.1e-20 73.1 1.8 9.2e-09 35.8 0.0 3.3 2 2 1 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 ABK74447.1 - 7e-11 41.7 33.9 2.9e-06 27.1 2.7 4.7 4 1 0 4 4 4 3 4Fe-4S binding domain Fer4_9 PF13187.6 ABK74447.1 - 1.1e-10 41.5 24.3 2e-06 27.8 7.2 3.3 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 ABK74447.1 - 6.7e-10 38.4 38.4 1.7e-05 24.4 4.8 5.1 6 0 0 6 6 5 4 4Fe-4S binding domain Fer4_10 PF13237.6 ABK74447.1 - 9.7e-10 38.4 23.9 9.3e-06 25.7 9.8 3.5 2 1 1 3 3 3 3 4Fe-4S dicluster domain Fer4_16 PF13484.6 ABK74447.1 - 1.5e-08 35.5 18.4 0.04 14.9 2.1 4.3 4 0 0 4 4 4 3 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 ABK74447.1 - 1.5e-08 34.2 31.6 0.00099 19.1 2.9 4.4 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_3 PF12798.7 ABK74447.1 - 6.5e-06 26.7 39.2 0.21 12.6 1.3 4.3 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_4 PF12800.7 ABK74447.1 - 0.0001 22.5 33.4 0.0085 16.5 3.7 4.5 4 1 0 4 4 4 2 4Fe-4S binding domain Fer4_8 PF13183.6 ABK74447.1 - 0.00048 20.5 23.5 0.0085 16.5 3.6 3.8 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 ABK74447.1 - 0.00086 19.4 26.4 0.13 12.4 11.5 4.1 4 1 1 5 5 5 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 ABK74447.1 - 0.001 19.6 21.5 1.1 9.8 0.4 4.2 3 1 0 3 3 3 3 4Fe-4S dicluster domain Fer4_15 PF13459.6 ABK74447.1 - 0.063 14.0 17.1 1.4 9.7 6.7 4.0 4 1 0 4 4 3 0 4Fe-4S single cluster domain Fer4_18 PF13746.6 ABK74447.1 - 2.7 8.2 18.7 0.27 11.4 1.9 3.8 2 1 2 4 4 4 0 4Fe-4S dicluster domain HTH_1 PF00126.27 ABK74448.1 - 1.2e-18 66.7 1.2 2.3e-17 62.7 0.5 2.8 3 0 0 3 3 3 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 ABK74448.1 - 1.1e-09 38.0 2.0 1.1e-09 38.0 2.0 1.8 1 1 1 2 2 2 1 LysR substrate binding domain MarR_2 PF12802.7 ABK74448.1 - 0.0016 18.3 0.1 0.005 16.7 0.1 1.8 1 0 0 1 1 1 1 MarR family HTH_30 PF13556.6 ABK74448.1 - 0.0034 17.1 0.1 0.018 14.8 0.0 2.1 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain HTH_20 PF12840.7 ABK74448.1 - 0.004 17.2 0.0 0.014 15.5 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain P22_Cro PF14549.6 ABK74448.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro HTH_AsnC-type PF13404.6 ABK74448.1 - 0.013 15.3 0.0 0.036 13.9 0.0 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 ABK74448.1 - 0.024 14.2 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 ABK74448.1 - 0.024 14.7 0.0 0.06 13.5 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain PEPCK_GTP PF00821.18 ABK74449.1 - 1.3e-171 570.3 0.1 1.5e-171 570.0 0.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 ABK74449.1 - 5.2e-101 336.8 0.0 6.7e-101 336.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain Peptidase_M42 PF05343.14 ABK74450.1 - 1.4e-43 149.1 0.0 1.7e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 ABK74450.1 - 4.7e-07 29.7 0.0 8.3e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 ABK74450.1 - 0.0052 16.5 0.0 0.013 15.2 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M28 His_Phos_1 PF00300.22 ABK74451.1 - 2.5e-08 33.8 0.1 1.1e-06 28.5 0.1 2.0 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) CN_hydrolase PF00795.22 ABK74452.1 - 4.9e-37 127.7 0.0 5.5e-37 127.5 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase tRNA-synt_2b PF00587.25 ABK74453.1 - 3.9e-38 131.2 0.0 5.2e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.15 ABK74453.1 - 1.5e-21 76.7 0.0 3e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain HGTP_anticodon PF03129.20 ABK74453.1 - 3.7e-14 52.7 0.0 1.1e-13 51.2 0.0 1.8 2 0 0 2 2 2 1 Anticodon binding domain DUF1198 PF06711.11 ABK74453.1 - 0.15 12.2 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1198) DNA_binding_1 PF01035.20 ABK74454.1 - 1.8e-34 117.7 0.0 2.4e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_1N PF02870.15 ABK74454.1 - 1.3e-10 41.9 0.0 1.8e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain Response_reg PF00072.24 ABK74456.1 - 3.8e-16 59.2 0.0 4.2e-16 59.1 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Acyl-CoA_dh_M PF02770.19 ABK74457.1 - 2.7e-19 69.2 0.0 5.1e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ABK74457.1 - 3.6e-19 69.5 0.1 8.8e-19 68.2 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 ABK74457.1 - 1.3e-09 38.4 0.6 5.2e-09 36.5 0.6 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Peptidase_M24 PF00557.24 ABK74459.1 - 6.3e-43 146.9 0.3 7.3e-43 146.7 0.3 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 Lipoprotein_9 PF03180.14 ABK74461.1 - 2.2e-35 121.9 0.0 2.8e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 NLPA lipoprotein zf-CCCH PF00642.24 ABK74462.1 - 0.17 11.9 0.2 0.25 11.3 0.2 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF4307 PF14155.6 ABK74463.1 - 3.4e-38 129.8 1.4 4e-38 129.6 1.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4307) DUF2157 PF09925.9 ABK74463.1 - 0.024 14.4 0.1 0.042 13.6 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Trp_oprn_chp PF09534.10 ABK74463.1 - 0.027 14.3 0.4 0.033 14.0 0.4 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) CwsA PF10814.8 ABK74463.1 - 0.068 13.3 0.4 0.13 12.5 0.4 1.4 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA Wzz PF02706.15 ABK74463.1 - 0.091 13.1 0.9 0.17 12.2 0.9 1.4 1 0 0 1 1 1 0 Chain length determinant protein DUF5353 PF17304.2 ABK74463.1 - 0.14 11.9 0.8 0.22 11.3 0.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5353) RskA PF10099.9 ABK74463.1 - 0.21 11.9 2.9 0.4 11.0 2.8 1.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Multi_Drug_Res PF00893.19 ABK74464.1 - 4.1e-17 62.6 6.2 5.1e-17 62.3 6.2 1.1 1 0 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 ABK74464.1 - 0.0029 17.8 11.4 0.0039 17.4 11.4 1.2 1 0 0 1 1 1 1 EamA-like transporter family DUF983 PF06170.12 ABK74464.1 - 0.86 10.1 5.8 0.28 11.6 2.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF983) PHO4 PF01384.20 ABK74464.1 - 1.2 8.1 9.5 1.5 7.8 9.5 1.1 1 0 0 1 1 1 0 Phosphate transporter family AA_permease_2 PF13520.6 ABK74465.1 - 6.4e-39 134.0 45.4 1.3e-38 132.9 45.5 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ABK74465.1 - 3.9e-30 104.9 41.7 7.3e-30 104.0 41.7 1.4 1 1 0 1 1 1 1 Amino acid permease Bac_luciferase PF00296.20 ABK74466.1 - 3.8e-28 98.8 7.6 6.9e-27 94.7 7.6 2.2 1 1 0 1 1 1 1 Luciferase-like monooxygenase DAHP_snth_FXD PF18152.1 ABK74466.1 - 0.11 12.4 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 DAHP synthase ferredoxin-like domain Amdase PF17645.1 ABK74467.1 - 2.1e-25 89.6 1.7 2.7e-25 89.3 1.7 1.1 1 0 0 1 1 1 1 Arylmalonate decarboxylase Asp_Glu_race PF01177.22 ABK74467.1 - 0.00015 21.7 0.5 0.00051 20.0 0.0 1.9 2 0 0 2 2 2 1 Asp/Glu/Hydantoin racemase IF2_N PF04760.15 ABK74467.1 - 0.052 13.4 0.0 0.31 10.9 0.0 2.2 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region HCV_NS4a PF01006.20 ABK74468.1 - 0.16 11.8 2.2 0.53 10.1 2.2 1.9 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a DUF2231 PF09990.9 ABK74468.1 - 0.16 12.4 3.0 0.23 11.9 1.3 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2231) IncE PF17627.2 ABK74468.1 - 0.26 11.3 2.0 0.35 10.9 1.7 1.4 1 1 0 1 1 1 0 Inclusion membrane protein E DUF202 PF02656.15 ABK74468.1 - 0.54 10.7 6.0 1.4 9.4 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Gram_pos_anchor PF00746.21 ABK74468.1 - 0.89 9.6 4.0 5.6 7.0 0.0 2.7 3 0 0 3 3 3 0 LPXTG cell wall anchor motif DUF2721 PF11026.8 ABK74469.1 - 0.0017 18.2 0.5 0.0024 17.8 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) DUF1772 PF08592.11 ABK74469.1 - 0.0029 17.9 5.1 0.0044 17.3 5.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) ABC2_membrane_2 PF12679.7 ABK74469.1 - 0.054 12.8 0.6 0.067 12.5 0.6 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein GHMP_kinases_N PF00288.26 ABK74469.1 - 0.12 12.6 0.3 0.32 11.3 0.3 1.7 1 1 0 1 1 1 0 GHMP kinases N terminal domain DUF4231 PF14015.6 ABK74469.1 - 0.24 11.9 1.6 0.36 11.3 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) DUF2892 PF11127.8 ABK74469.1 - 0.32 11.0 2.2 0.66 10.1 2.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) Acyl-CoA_dh_1 PF00441.24 ABK74470.1 - 2.3e-17 63.6 4.0 2.3e-17 63.6 4.0 1.9 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 ABK74470.1 - 1.4e-05 25.4 4.5 1.4e-05 25.4 4.5 2.1 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain AMP-binding PF00501.28 ABK74471.1 - 2.1e-47 161.7 0.6 4.9e-41 140.7 0.0 2.0 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 ABK74471.1 - 6e-16 59.2 0.0 2.1e-15 57.5 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ABC_tran PF00005.27 ABK74472.1 - 6.6e-30 104.4 0.0 1.1e-29 103.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK74472.1 - 4.2e-06 26.8 0.2 0.0067 16.3 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK74472.1 - 4.9e-06 26.1 0.1 0.088 12.2 0.1 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 ABK74472.1 - 5e-05 23.3 0.0 0.0001 22.2 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 ABK74472.1 - 0.0033 17.2 0.1 0.018 14.7 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ABK74472.1 - 0.0034 17.1 0.1 0.007 16.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ABK74472.1 - 0.0048 17.0 0.0 0.0075 16.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 ABK74472.1 - 0.0054 17.1 0.3 0.0066 16.8 0.3 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ABK74472.1 - 0.0064 16.8 0.1 0.011 16.0 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 ABK74472.1 - 0.0066 16.9 0.1 0.043 14.2 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 ABK74472.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_25 PF13481.6 ABK74472.1 - 0.012 15.2 1.4 0.03 13.9 0.1 2.2 2 2 0 2 2 2 0 AAA domain PhoH PF02562.16 ABK74472.1 - 0.022 14.2 0.0 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.22 ABK74472.1 - 0.024 13.9 0.2 0.047 12.9 0.1 1.5 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.6 ABK74472.1 - 0.027 14.7 0.1 0.068 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 ABK74472.1 - 0.031 14.8 0.0 0.049 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ABK74472.1 - 0.041 13.8 0.1 0.081 12.8 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 ABK74472.1 - 0.09 12.9 1.8 0.43 10.7 1.8 2.1 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 ABK74472.1 - 0.11 12.4 0.0 0.31 10.9 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 ABK74472.1 - 0.13 12.6 0.1 0.49 10.8 0.1 2.0 1 0 0 1 1 1 0 RNA helicase ADH_N PF08240.12 ABK74473.1 - 6.9e-24 83.8 1.3 1.6e-23 82.6 0.5 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ABK74473.1 - 5e-14 52.4 0.3 1.9e-13 50.6 0.3 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ABK74473.1 - 3.5e-12 46.3 0.3 6.5e-12 45.4 0.3 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 ABK74473.1 - 3e-06 26.7 2.1 4.4e-06 26.2 2.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ABK74473.1 - 0.0092 15.4 0.1 0.016 14.6 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 ABK74473.1 - 0.014 14.6 0.6 0.021 14.1 0.6 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 ABK74473.1 - 0.017 15.2 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 ABK74473.1 - 0.02 15.0 0.3 0.041 14.0 0.3 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Pyr_redox PF00070.27 ABK74473.1 - 0.03 14.9 0.3 0.063 13.8 0.3 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 ABK74473.1 - 0.033 13.8 0.0 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GFO_IDH_MocA PF01408.22 ABK74473.1 - 0.036 14.9 0.1 0.07 14.0 0.1 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 ABK74473.1 - 0.097 12.9 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ADH_N_2 PF16884.5 ABK74473.1 - 0.16 11.9 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase GIDA PF01134.22 ABK74473.1 - 0.23 10.5 1.0 0.3 10.1 1.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A adh_short PF00106.25 ABK74474.1 - 1.4e-45 155.2 0.8 1.7e-45 154.9 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK74474.1 - 1.4e-33 116.5 2.7 1.7e-33 116.1 2.7 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK74474.1 - 1.4e-10 41.4 0.3 2.1e-10 40.8 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK74474.1 - 6.4e-05 22.5 0.1 0.0016 18.0 0.1 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ABK74474.1 - 0.0076 15.7 0.0 0.019 14.4 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase DUF1776 PF08643.10 ABK74474.1 - 0.062 12.7 0.0 0.088 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.26 ABK74474.1 - 0.32 11.0 3.6 1.9 8.5 3.6 2.3 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Transglycosylas PF06737.14 ABK74475.1 - 1.5e-35 121.7 6.4 3.8e-35 120.4 6.4 1.7 1 0 0 1 1 1 1 Transglycosylase-like domain Mur_ligase_M PF08245.12 ABK74476.1 - 4.3e-46 157.3 0.0 5.8e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 ABK74476.1 - 8.9e-23 80.4 0.0 1.8e-21 76.2 0.0 2.7 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Mur_ligase PF01225.25 ABK74476.1 - 1.9e-08 34.5 2.9 2.4e-08 34.2 0.1 2.6 3 0 0 3 3 3 1 Mur ligase family, catalytic domain Phosphodiest PF01663.22 ABK74477.1 - 2.7e-31 109.5 0.2 5.6e-30 105.1 0.2 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 ABK74477.1 - 0.0037 16.7 0.2 0.015 14.7 0.1 1.9 2 0 0 2 2 2 1 Metalloenzyme superfamily 4HBT PF03061.22 ABK74479.1 - 3.4e-05 24.1 1.4 4.9e-05 23.6 0.4 1.8 2 0 0 2 2 2 1 Thioesterase superfamily PTS_EIIC PF02378.18 ABK74482.1 - 1.7e-72 244.2 26.6 1.7e-72 244.2 26.6 1.9 2 1 0 2 2 2 1 Phosphotransferase system, EIIC PTS_EIIB PF00367.20 ABK74482.1 - 2.3e-13 49.4 0.2 3.8e-13 48.7 0.2 1.4 1 0 0 1 1 1 1 phosphotransferase system, EIIB OAD_gamma PF04277.13 ABK74482.1 - 0.016 15.8 1.3 0.025 15.1 0.1 2.0 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain CbiQ PF02361.16 ABK74483.1 - 1.2e-35 123.1 5.9 1.7e-35 122.7 5.9 1.1 1 0 0 1 1 1 1 Cobalt transport protein UvrD-helicase PF00580.21 ABK74484.1 - 5.9e-41 141.0 0.0 1.2e-40 140.0 0.0 1.5 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 ABK74484.1 - 6e-33 114.7 0.0 4.9e-19 68.9 0.0 2.0 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 ABK74484.1 - 7.8e-21 74.9 0.1 1.6e-20 73.9 0.1 1.6 1 0 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.7 ABK74484.1 - 2.4e-14 53.9 0.0 1.6e-13 51.1 0.0 2.4 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily UvrD_C_2 PF13538.6 ABK74484.1 - 5e-10 39.1 0.8 0.00058 19.6 0.1 2.6 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 ABK74484.1 - 0.0026 17.5 7.4 0.0055 16.4 1.9 3.0 3 0 0 3 3 3 1 AAA domain Exonuc_V_gamma PF04257.14 ABK74484.1 - 0.11 10.7 0.0 0.21 9.8 0.0 1.4 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit GMC_oxred_C PF05199.13 ABK74485.1 - 4.5e-20 72.6 0.0 8.9e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 ABK74485.1 - 2.1e-09 37.2 0.0 4.9e-09 36.0 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ABK74485.1 - 3.4e-07 29.7 1.5 6e-07 28.9 0.9 1.7 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 ABK74485.1 - 1.2e-05 24.6 0.3 1.7e-05 24.1 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 ABK74485.1 - 8.2e-05 22.0 1.8 0.00029 20.2 0.3 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ABK74485.1 - 0.00032 20.4 7.2 0.0092 15.6 7.2 2.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ABK74485.1 - 0.0013 18.9 0.9 0.0013 18.9 0.9 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 ABK74485.1 - 0.0015 17.8 0.3 0.0025 17.1 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 ABK74485.1 - 0.0015 17.9 4.7 0.0057 16.1 5.3 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ABK74485.1 - 0.0044 16.1 1.5 0.0054 15.8 0.4 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 ABK74485.1 - 0.0055 15.5 0.8 0.01 14.6 0.8 1.4 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 ABK74485.1 - 0.019 14.2 0.6 0.03 13.6 0.6 1.3 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 ABK74485.1 - 0.02 14.2 0.3 0.037 13.3 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 ABK74485.1 - 0.066 13.1 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 ABK74485.1 - 1.6 7.5 2.9 2.4 6.9 2.9 1.2 1 0 0 1 1 1 0 Tryptophan halogenase DUF2171 PF09939.9 ABK74486.1 - 0.022 15.0 0.5 0.14 12.4 0.5 2.1 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2171) UPF0029 PF01205.19 ABK74487.1 - 4.4e-27 94.5 0.0 6.5e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 DUF1949 PF09186.11 ABK74487.1 - 5.2e-10 39.1 0.1 1e-09 38.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1949) Mce4_CUP1 PF11887.8 ABK74488.1 - 3.1e-107 357.8 0.0 4.2e-107 357.4 0.0 1.2 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative MlaD PF02470.20 ABK74488.1 - 1.5e-14 54.0 0.0 5.8e-13 48.9 0.0 2.4 2 0 0 2 2 2 1 MlaD protein FixS PF03597.15 ABK74488.1 - 0.013 15.2 0.4 0.025 14.3 0.4 1.5 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type SBP_bac_6 PF13343.6 ABK74489.1 - 1.3e-29 103.4 0.2 1.9e-29 102.8 0.2 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 ABK74489.1 - 1.5e-16 61.1 3.1 1.5e-16 61.0 1.5 1.7 1 1 1 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 ABK74489.1 - 7.2e-07 29.2 0.4 1.2e-06 28.5 0.4 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein F420H2_quin_red PF04075.14 ABK74490.1 - 4.6e-10 39.7 0.1 5.9e-10 39.4 0.1 1.1 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase Acyl-CoA_dh_N PF02771.16 ABK74491.1 - 3.1e-23 82.6 0.2 5.9e-23 81.7 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ABK74491.1 - 2.2e-19 69.4 0.0 5.2e-19 68.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 ABK74491.1 - 2.6e-08 34.2 0.2 7.2e-08 32.8 0.2 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 ABK74491.1 - 0.21 11.2 1.4 1.3 8.6 1.4 2.0 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Acyl-CoA_ox_N PF14749.6 ABK74491.1 - 0.22 12.1 0.0 0.36 11.4 0.0 1.3 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Thioredoxin PF00085.20 ABK74492.1 - 8e-11 41.8 0.0 1.1e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ABK74492.1 - 0.00025 21.5 0.0 0.00079 19.8 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 ABK74492.1 - 0.0055 16.5 0.0 0.0067 16.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.24 ABK74492.1 - 0.017 15.4 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin AhpC-TSA PF00578.21 ABK74492.1 - 0.025 14.5 0.0 5.3 7.0 0.0 2.1 1 1 1 2 2 2 0 AhpC/TSA family Thioredoxin_8 PF13905.6 ABK74492.1 - 0.035 14.4 0.0 0.29 11.5 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin-like FTR1 PF03239.14 ABK74492.1 - 0.039 13.1 0.9 0.048 12.8 0.9 1.1 1 0 0 1 1 1 0 Iron permease FTR1 family Thioredoxin_3 PF13192.6 ABK74492.1 - 0.092 12.8 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain ECH_1 PF00378.20 ABK74493.1 - 1.3e-40 139.3 0.1 1.5e-40 139.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK74493.1 - 4.1e-28 98.8 0.0 4.8e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF3556 PF12077.8 ABK74494.1 - 3.8e-282 936.9 7.2 4.4e-282 936.7 7.2 1.0 1 0 0 1 1 1 1 Transmembrane protein of unknown function (DUF3556) FUSC PF04632.12 ABK74494.1 - 5.5 5.4 12.4 10 4.5 12.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family FtsK_SpoIIIE PF01580.18 ABK74495.1 - 9.7e-47 159.4 0.0 2.9e-44 151.3 0.0 3.1 2 1 0 2 2 2 1 FtsK/SpoIIIE family AAA_10 PF12846.7 ABK74495.1 - 0.00032 19.7 0.0 0.11 11.3 0.0 2.1 2 0 0 2 2 2 2 AAA-like domain AAA_22 PF13401.6 ABK74495.1 - 0.00038 20.7 0.0 0.00085 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF87 PF01935.17 ABK74495.1 - 0.011 15.9 0.1 0.019 15.0 0.1 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain FTR PF01913.18 ABK74495.1 - 0.1 12.5 0.0 2.3 8.2 0.0 2.3 2 0 0 2 2 2 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase TrwB_AAD_bind PF10412.9 ABK74495.1 - 0.13 11.1 0.2 0.23 10.3 0.2 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Pox_A32 PF04665.12 ABK74495.1 - 0.25 10.8 0.0 0.39 10.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein HEM4 PF02602.15 ABK74496.1 - 8.5e-42 143.1 0.0 1.1e-41 142.7 0.0 1.2 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Trans_reg_C PF00486.28 ABK74496.1 - 3.5e-10 39.8 0.0 1.2e-09 38.1 0.0 1.9 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Peripla_BP_6 PF13458.6 ABK74496.1 - 0.0011 18.7 0.1 0.0016 18.2 0.1 1.3 1 0 0 1 1 1 1 Periplasmic binding protein adh_short PF00106.25 ABK74497.1 - 4.6e-41 140.4 1.5 2.4e-39 134.8 1.5 2.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK74497.1 - 4e-32 111.6 3.2 1.8e-30 106.2 3.2 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK74497.1 - 4e-09 36.6 0.1 5.3e-09 36.2 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK74497.1 - 0.0015 18.1 0.1 0.0025 17.3 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 ABK74497.1 - 0.0018 17.6 0.1 0.16 11.3 0.0 2.5 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.6 ABK74497.1 - 0.071 13.0 0.3 0.11 12.4 0.3 1.5 1 0 0 1 1 1 0 NAD(P)H-binding DFP PF04127.15 ABK74497.1 - 2.1 8.2 4.6 5.2 6.9 0.0 2.4 2 1 0 3 3 3 0 DNA / pantothenate metabolism flavoprotein HTH_30 PF13556.6 ABK74498.1 - 1.3e-19 69.7 1.0 5e-19 67.9 0.6 2.3 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain GAF_2 PF13185.6 ABK74498.1 - 1.5e-16 61.0 0.4 3.4e-13 50.1 0.1 2.6 2 0 0 2 2 2 2 GAF domain GGDEF_2 PF17853.1 ABK74498.1 - 9.4e-12 45.2 4.5 2.8e-11 43.7 0.1 3.3 3 0 0 3 3 3 1 GGDEF-like domain GAF PF01590.26 ABK74498.1 - 4.1e-11 43.6 0.1 9.8e-10 39.2 0.0 2.5 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 ABK74498.1 - 9.3e-07 29.3 0.1 6.8e-05 23.2 0.0 3.2 2 2 0 2 2 2 1 GAF domain YqeY PF09424.10 ABK74499.1 - 5.6e-46 156.2 6.2 6.3e-46 156.0 6.2 1.0 1 0 0 1 1 1 1 Yqey-like protein GatB_Yqey PF02637.18 ABK74499.1 - 0.0016 18.3 2.9 0.029 14.2 2.9 2.2 1 1 0 1 1 1 1 GatB domain Phage-MuB_C PF09077.11 ABK74499.1 - 0.0045 16.8 1.4 0.0045 16.8 1.4 2.8 2 1 0 3 3 3 1 Mu B transposition protein, C terminal UPF0154 PF03672.13 ABK74499.1 - 0.032 14.3 0.4 0.073 13.1 0.4 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) Glyco_trans_4_4 PF13579.6 ABK74499.1 - 0.052 14.0 1.7 0.072 13.5 1.7 1.2 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain EamA PF00892.20 ABK74500.1 - 4.4e-11 43.1 32.1 7.4e-11 42.4 9.7 2.2 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.6 ABK74500.1 - 0.0069 16.0 0.8 0.0069 16.0 0.8 2.3 1 1 1 2 2 2 2 Putative multidrug resistance efflux transporter Orn_Arg_deC_N PF02784.16 ABK74501.1 - 9.2e-35 120.2 0.0 1.1e-34 119.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 ABK74501.1 - 1.2e-11 44.7 0.0 1.8e-11 44.1 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 ABK74501.1 - 0.05 13.2 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 Alanine racemase, N-terminal domain DUF3652 PF12372.8 ABK74501.1 - 0.11 12.5 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 Huntingtin protein region HAD_2 PF13419.6 ABK74502.1 - 4.5e-13 49.7 0.0 6.4e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ABK74502.1 - 2.3e-05 24.8 0.0 6.2e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ABK74502.1 - 5.8e-05 23.6 0.2 8.3e-05 23.1 0.2 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase FAD_binding_2 PF00890.24 ABK74503.1 - 2.7e-57 194.7 4.5 3.4e-57 194.4 4.5 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ABK74503.1 - 1.1e-12 48.3 10.6 9.1e-12 45.2 10.6 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ABK74503.1 - 2.8e-10 40.1 0.5 1.5e-08 34.5 1.6 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ABK74503.1 - 2.9e-10 39.4 6.6 4e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 ABK74503.1 - 2.5e-07 30.2 2.1 1.7e-05 24.2 0.6 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ABK74503.1 - 0.0017 17.6 3.7 0.0052 16.0 3.6 1.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 ABK74503.1 - 0.016 14.5 4.1 4.3 6.5 4.0 2.2 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 ABK74503.1 - 0.018 14.2 10.0 2.1 7.3 8.4 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Amino_oxidase PF01593.24 ABK74503.1 - 0.031 13.6 1.1 0.16 11.3 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ABK74503.1 - 0.05 13.8 6.9 0.17 12.2 6.9 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ABK74503.1 - 0.059 13.9 5.3 0.32 11.6 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ABK74503.1 - 0.21 10.8 6.0 0.39 10.0 6.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 ABK74503.1 - 1.4 8.1 2.8 30 3.7 1.3 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiS PF02597.20 ABK74504.1 - 7.9e-19 68.1 0.0 8.9e-19 67.9 0.0 1.0 1 0 0 1 1 1 1 ThiS family Pec_lyase_C PF00544.19 ABK74504.1 - 0.018 14.6 0.0 0.019 14.6 0.0 1.1 1 0 0 1 1 1 0 Pectate lyase Lambda_tail_I PF06805.12 ABK74504.1 - 0.034 14.5 0.0 0.057 13.8 0.0 1.4 1 1 0 1 1 1 0 Bacteriophage lambda tail assembly protein I Urm1 PF09138.11 ABK74504.1 - 0.041 14.2 0.0 0.046 14.1 0.0 1.2 1 0 0 1 1 1 0 Urm1 (Ubiquitin related modifier) LysR_substrate PF03466.20 ABK74505.1 - 1.4e-30 106.2 6.2 1.7e-30 105.9 6.2 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 ABK74505.1 - 1.6e-17 63.2 0.1 2.9e-17 62.4 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_28 PF13518.6 ABK74505.1 - 0.043 13.9 0.2 0.13 12.4 0.2 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain AAA PF00004.29 ABK74506.1 - 9.6e-22 77.8 0.0 1.9e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 ABK74506.1 - 3e-07 30.5 0.4 1e-06 28.8 0.4 2.0 1 0 0 1 1 1 1 AAA lid domain Mg_chelatase PF01078.21 ABK74506.1 - 1.6e-06 27.6 0.7 2.3e-05 23.9 0.2 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 ABK74506.1 - 6.1e-06 26.1 0.2 1.8e-05 24.5 0.2 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ABK74506.1 - 0.00016 21.9 0.2 0.047 14.0 0.0 2.7 2 1 1 3 3 2 1 AAA domain AAA_16 PF13191.6 ABK74506.1 - 0.00023 21.6 0.1 0.00098 19.5 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 ABK74506.1 - 0.00044 20.0 0.7 0.0015 18.3 0.5 2.1 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 ABK74506.1 - 0.0017 18.4 0.0 0.0061 16.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 ABK74506.1 - 0.0036 17.5 0.3 0.016 15.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ABK74506.1 - 0.004 17.7 0.0 0.011 16.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ABK74506.1 - 0.0085 16.4 0.0 0.023 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 ABK74506.1 - 0.014 15.8 0.0 0.027 14.8 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 ABK74506.1 - 0.017 14.9 0.2 0.38 10.5 0.1 2.3 1 1 1 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 ABK74506.1 - 0.017 14.7 0.1 0.054 13.1 0.1 1.9 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 ABK74506.1 - 0.036 13.8 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 ABK74506.1 - 0.037 13.9 0.1 0.07 13.0 0.1 1.4 1 0 0 1 1 1 0 NTPase AAA_28 PF13521.6 ABK74506.1 - 0.043 14.1 0.5 0.3 11.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ABK74506.1 - 0.05 13.1 0.1 0.088 12.3 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 ABK74506.1 - 0.051 13.3 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ResIII PF04851.15 ABK74506.1 - 0.11 12.5 0.2 0.42 10.6 0.2 1.8 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit TIP49 PF06068.13 ABK74506.1 - 0.12 11.5 0.5 0.97 8.6 0.5 2.0 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_2 PF07724.14 ABK74506.1 - 0.15 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.6 ABK74506.1 - 0.19 11.8 0.0 0.76 9.9 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain FCD PF07729.12 ABK74507.1 - 7.2e-21 74.9 10.2 7.2e-21 74.9 10.2 1.5 2 0 0 2 2 2 1 FCD domain GntR PF00392.21 ABK74507.1 - 1.7e-15 56.4 0.1 3.1e-15 55.6 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 ABK74507.1 - 0.00027 20.4 0.3 0.0013 18.2 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 ABK74507.1 - 0.01 15.7 0.0 0.025 14.5 0.0 1.8 1 0 0 1 1 1 0 HTH domain HTH_41 PF14502.6 ABK74507.1 - 0.074 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain FmdA_AmdA PF03069.15 ABK74508.1 - 2.5e-167 556.4 0.0 2.9e-167 556.2 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family WYL PF13280.6 ABK74509.1 - 1.1e-35 123.2 0.0 1.6e-35 122.7 0.0 1.2 1 0 0 1 1 1 1 WYL domain DUF1840 PF08895.11 ABK74509.1 - 0.026 14.9 0.0 0.046 14.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) IclR PF01614.18 ABK74510.1 - 7e-24 84.1 0.1 1.2e-23 83.4 0.1 1.4 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 ABK74510.1 - 2.3e-14 52.9 0.2 4.4e-14 52.0 0.2 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 ABK74510.1 - 1.2e-08 34.8 0.2 3.4e-08 33.3 0.2 1.8 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 ABK74510.1 - 6.2e-07 29.8 0.1 3.1e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 Winged helix DNA-binding domain Rrf2 PF02082.20 ABK74510.1 - 0.0017 18.7 0.0 0.0039 17.5 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator DUF742 PF05331.11 ABK74510.1 - 0.0074 16.1 0.1 0.023 14.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF742) TrmB PF01978.19 ABK74510.1 - 0.0094 15.8 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.20 ABK74510.1 - 0.02 14.8 0.0 0.044 13.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 ABK74510.1 - 0.03 13.9 0.0 0.061 12.9 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding SMC_Nse1 PF07574.13 ABK74510.1 - 0.031 14.2 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex Penicillinase_R PF03965.16 ABK74510.1 - 0.16 12.4 0.0 0.54 10.6 0.0 1.8 2 0 0 2 2 2 0 Penicillinase repressor FeoC PF09012.10 ABK74510.1 - 0.18 11.9 0.0 0.41 10.8 0.0 1.5 1 0 0 1 1 1 0 FeoC like transcriptional regulator Adenine_glyco PF03352.13 ABK74511.1 - 1.2e-68 230.4 0.0 1.5e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 Methyladenine glycosylase HhH-GPD PF00730.25 ABK74511.1 - 0.012 16.1 0.0 0.016 15.7 0.0 1.3 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein Acyl-CoA_dh_N PF02771.16 ABK74512.1 - 1.5e-28 99.7 0.7 1.5e-28 99.7 0.7 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 ABK74512.1 - 1.3e-26 93.7 2.5 1.3e-26 93.7 2.5 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK74512.1 - 8.2e-18 64.4 0.0 1.5e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ABK74512.1 - 4.4e-10 39.9 2.9 4.4e-10 39.9 2.9 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Fasciclin PF02469.22 ABK74513.1 - 6.9e-17 61.9 0.0 9.5e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain Peptidase_M50 PF02163.22 ABK74514.1 - 6.6e-08 32.1 9.6 0.0016 17.8 0.3 3.0 1 1 1 2 2 2 2 Peptidase family M50 Bac_luciferase PF00296.20 ABK74515.1 - 6.3e-15 55.4 6.0 2e-11 43.9 0.3 2.4 1 1 1 2 2 2 2 Luciferase-like monooxygenase Response_reg PF00072.24 ABK74516.1 - 1.4e-17 63.9 0.1 2.3e-17 63.2 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 ABK74516.1 - 3.3e-15 55.4 0.1 5.6e-15 54.6 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 ABK74516.1 - 2e-06 27.4 0.1 3.8e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 ABK74516.1 - 0.0095 15.7 0.1 0.022 14.5 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_40 PF14493.6 ABK74516.1 - 0.028 14.9 0.1 0.098 13.1 0.1 1.9 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_29 PF13551.6 ABK74516.1 - 0.05 13.6 0.2 0.97 9.5 0.1 2.8 2 0 0 2 2 2 0 Winged helix-turn helix MFS_1 PF07690.16 ABK74517.1 - 3.7e-22 78.7 64.4 6.1e-14 51.7 33.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK74517.1 - 3e-20 72.5 33.6 4.2e-17 62.2 9.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter PucR PF07905.11 ABK74518.1 - 1.6e-29 102.6 0.0 4.8e-29 101.0 0.0 1.9 1 0 0 1 1 1 1 Purine catabolism regulatory protein-like family HTH_30 PF13556.6 ABK74518.1 - 7.1e-14 51.3 3.9 2.2e-13 49.8 0.3 2.7 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain GGDEF_2 PF17853.1 ABK74518.1 - 1.5e-09 38.2 16.4 2.6e-09 37.3 4.6 3.5 2 1 1 3 3 3 2 GGDEF-like domain HTH_1 PF00126.27 ABK74518.1 - 0.0012 18.7 1.5 0.055 13.4 0.1 2.9 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_8 PF02954.19 ABK74518.1 - 0.013 15.3 0.5 0.013 15.3 0.5 2.6 3 0 0 3 3 3 0 Bacterial regulatory protein, Fis family DUF2089 PF09862.9 ABK74518.1 - 0.019 15.0 0.0 0.046 13.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) DUF3933 PF13069.6 ABK74518.1 - 0.047 13.6 0.1 0.13 12.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3933) DUF4335 PF14233.6 ABK74518.1 - 0.15 11.9 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) ABC_tran PF00005.27 ABK74519.1 - 2.7e-30 105.7 0.0 3.3e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK74519.1 - 3.3e-11 43.5 1.1 2.3e-07 30.9 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK74519.1 - 8.1e-08 32.0 0.0 4.9e-07 29.4 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ABK74519.1 - 0.0045 16.7 0.1 0.0087 15.8 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 ABK74519.1 - 0.005 16.6 0.1 0.012 15.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 ABK74519.1 - 0.0072 16.9 0.0 0.0096 16.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ABK74519.1 - 0.013 15.8 0.0 0.037 14.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ABK74519.1 - 0.026 14.9 0.6 0.054 13.9 0.6 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 ABK74519.1 - 0.034 14.5 0.0 0.049 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ABK74519.1 - 0.042 14.1 0.0 0.088 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ABK74519.1 - 0.043 13.4 2.0 0.16 11.5 1.9 2.1 1 1 0 1 1 1 0 AAA domain DLIC PF05783.11 ABK74519.1 - 0.046 12.6 0.0 0.063 12.1 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_24 PF13479.6 ABK74519.1 - 0.051 13.3 0.1 0.077 12.7 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ABK74519.1 - 0.098 12.8 0.5 0.44 10.7 0.5 1.9 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 ABK74519.1 - 0.1 12.0 0.2 0.78 9.1 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 ABK74519.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 NTPase DUF3584 PF12128.8 ABK74519.1 - 0.13 9.8 0.1 0.16 9.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) RsgA_GTPase PF03193.16 ABK74519.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_15 PF13175.6 ABK74519.1 - 0.23 11.1 0.0 15 5.2 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain GalKase_gal_bdg PF10509.9 ABK74520.1 - 9.2e-15 53.9 0.1 2.5e-14 52.6 0.1 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 ABK74520.1 - 3.2e-13 49.7 0.7 9.3e-13 48.2 0.7 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 ABK74520.1 - 3.7e-13 49.6 0.2 1.2e-12 48.0 0.2 1.9 1 1 0 1 1 1 1 GHMP kinases C terminal FoP_duplication PF13865.6 ABK74521.1 - 6 7.5 9.4 7.5 7.2 9.4 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Tex_N PF09371.10 ABK74522.1 - 3.8e-71 238.5 0.8 7.2e-71 237.6 0.8 1.4 1 0 0 1 1 1 1 Tex-like protein N-terminal domain Tex_YqgF PF16921.5 ABK74522.1 - 9.9e-51 171.4 0.0 1.9e-50 170.5 0.0 1.5 1 0 0 1 1 1 1 Tex protein YqgF-like domain HHH_3 PF12836.7 ABK74522.1 - 1.2e-27 96.0 0.0 2.3e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_9 PF17674.1 ABK74522.1 - 1.1e-23 83.9 0.0 3.1e-23 82.5 0.0 1.9 1 0 0 1 1 1 1 HHH domain S1 PF00575.23 ABK74522.1 - 7.8e-20 71.0 3.2 1.4e-19 70.2 3.2 1.5 1 0 0 1 1 1 1 S1 RNA binding domain YqgF PF14639.6 ABK74522.1 - 3.9e-07 30.0 0.0 2.4e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 ABK74522.1 - 6.5e-06 26.4 0.0 1.4e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif T2SSK PF03934.13 ABK74522.1 - 0.0023 17.4 0.2 0.0064 15.9 0.0 1.8 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein K HHH_6 PF14579.6 ABK74522.1 - 0.0046 17.2 0.0 0.016 15.5 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 ABK74522.1 - 0.0096 15.8 0.0 0.035 14.0 0.0 2.1 1 0 0 1 1 1 1 Helix-hairpin-helix motif Viral_P18 PF04521.13 ABK74522.1 - 0.097 12.5 0.1 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein UreE_N PF02814.15 ABK74523.1 - 5.2e-14 51.6 4.0 1.1e-13 50.5 4.0 1.6 1 0 0 1 1 1 1 UreE urease accessory protein, N-terminal domain DUF2218 PF09981.9 ABK74523.1 - 0.11 12.9 1.6 2.8 8.4 0.2 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2218) DLH PF01738.18 ABK74524.1 - 2.5e-51 174.3 0.0 2.8e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 ABK74524.1 - 1e-05 25.6 0.9 0.21 11.5 0.0 2.8 2 1 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Chlorophyllase PF07224.11 ABK74524.1 - 0.023 13.7 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Peptidase_S9 PF00326.21 ABK74524.1 - 0.1 12.1 0.0 6.3 6.2 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 ABK74524.1 - 0.52 10.9 5.8 0.97 10.0 5.8 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family CbiA PF01656.23 ABK74525.1 - 8.3e-12 45.3 0.0 1.6e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 ABK74525.1 - 1.2e-10 41.6 0.0 1.9e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 ABK74525.1 - 4.5e-06 26.3 0.1 1.7e-05 24.4 0.1 1.8 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ArsA_ATPase PF02374.15 ABK74525.1 - 0.00013 21.2 0.0 0.00022 20.5 0.0 1.3 1 0 0 1 1 1 1 Anion-transporting ATPase ParA PF10609.9 ABK74525.1 - 0.00055 19.5 0.1 0.00082 18.9 0.1 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 ABK74525.1 - 0.016 14.7 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family RE_XamI PF09572.10 ABK74525.1 - 0.066 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 XamI restriction endonuclease MarR PF01047.22 ABK74526.1 - 6.6e-11 42.0 0.0 4.6e-10 39.3 0.0 2.0 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.7 ABK74526.1 - 1.9e-10 40.5 0.4 2.3e-09 37.0 0.0 2.3 3 0 0 3 3 3 1 MarR family HTH_27 PF13463.6 ABK74526.1 - 2.7e-08 34.2 0.0 7.6e-08 32.7 0.0 1.7 3 0 0 3 3 3 1 Winged helix DNA-binding domain Rrf2 PF02082.20 ABK74526.1 - 0.047 14.0 0.0 0.64 10.4 0.0 2.4 2 1 0 2 2 2 0 Transcriptional regulator MaoC_dehydrat_N PF13452.6 ABK74527.1 - 7.3e-31 107.0 0.0 9.9e-31 106.6 0.0 1.2 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase MaoC_dehydratas PF01575.19 ABK74527.1 - 0.0024 17.5 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain Patatin PF01734.22 ABK74528.1 - 1.7e-16 61.0 7.9 7e-15 55.8 7.9 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase ABC_membrane PF00664.23 ABK74529.1 - 6.6e-27 94.8 2.2 8.8e-27 94.4 2.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 ABK74529.1 - 1.6e-11 44.8 0.0 2.9e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter PepX_C PF08530.10 ABK74529.1 - 0.031 14.2 0.2 0.065 13.2 0.2 1.5 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain OATP PF03137.20 ABK74529.1 - 1.6 7.0 4.1 13 3.9 0.1 2.6 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family GtrA PF04138.14 ABK74530.1 - 8.6e-20 71.1 10.5 1.1e-19 70.8 10.5 1.1 1 0 0 1 1 1 1 GtrA-like protein DUF4126 PF13548.6 ABK74531.1 - 1.8e-52 177.6 27.6 2.1e-52 177.4 27.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4126) DUF3318 PF11780.8 ABK74531.1 - 0.01 15.8 0.3 0.01 15.8 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3318) DUF4448 PF14610.6 ABK74531.1 - 1.3 8.8 2.9 0.9 9.3 1.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) DUF2207 PF09972.9 ABK74531.1 - 6.5 5.4 7.2 0.29 9.9 1.3 1.6 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF4381 PF14316.6 ABK74531.1 - 8.9 6.5 17.1 0.24 11.7 2.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) HNH_4 PF13395.6 ABK74532.1 - 7.4e-11 41.8 0.0 1.5e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease HNH PF01844.23 ABK74532.1 - 1.5e-07 31.5 0.1 2.5e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 HNH endonuclease HNH_5 PF14279.6 ABK74532.1 - 1e-06 28.5 0.0 1.7e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 HNH endonuclease BPD_transp_1 PF00528.22 ABK74533.1 - 1.7e-16 60.5 16.5 1.7e-16 60.5 16.5 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF3796 PF12676.7 ABK74533.1 - 0.034 14.6 0.3 0.074 13.5 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) Anoctamin PF04547.12 ABK74533.1 - 0.082 11.7 0.1 0.082 11.7 0.1 2.1 1 1 0 2 2 2 0 Calcium-activated chloride channel TMEM251 PF15190.6 ABK74533.1 - 0.18 11.7 0.0 0.18 11.7 0.0 2.6 3 0 0 3 3 3 0 Transmembrane protein 251 RibD_C PF01872.17 ABK74534.1 - 3.1e-42 144.7 0.1 3.9e-42 144.3 0.1 1.1 1 0 0 1 1 1 1 RibD C-terminal domain UDPG_MGDP_dh_N PF03721.14 ABK74535.1 - 1.7e-60 203.8 0.0 3.4e-60 202.8 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 ABK74535.1 - 1.4e-31 108.5 0.0 4.2e-31 107.0 0.0 1.8 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 ABK74535.1 - 3.8e-29 101.2 0.3 3.7e-28 98.0 0.0 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain F420_oxidored PF03807.17 ABK74535.1 - 6.2e-09 36.3 0.4 0.034 14.7 0.0 3.8 3 1 0 3 3 3 3 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 ABK74535.1 - 6.3e-06 26.4 1.3 0.0071 16.5 0.1 3.8 3 1 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 ABK74535.1 - 0.065 13.1 0.0 0.24 11.3 0.0 2.0 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 ABK74536.1 - 2.5e-56 190.8 3.5 2.8e-56 190.7 3.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK74536.1 - 5.2e-46 156.6 0.8 6.5e-46 156.3 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK74536.1 - 1.7e-11 44.4 0.7 2.4e-11 43.9 0.7 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK74536.1 - 0.00018 21.0 0.2 0.00064 19.3 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family IclR PF01614.18 ABK74537.1 - 7.1e-24 84.1 0.0 1.1e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 ABK74537.1 - 7.7e-11 41.6 0.1 3.6e-10 39.5 0.0 2.1 2 0 0 2 2 2 1 IclR helix-turn-helix domain AbiEi_4 PF13338.6 ABK74537.1 - 5.2e-05 23.3 0.1 0.00029 20.9 0.0 2.2 2 0 0 2 2 2 1 Transcriptional regulator, AbiEi antitoxin MarR_2 PF12802.7 ABK74537.1 - 0.00027 20.8 0.5 0.0017 18.2 0.0 2.4 3 0 0 3 3 3 1 MarR family HTH_24 PF13412.6 ABK74537.1 - 0.00032 20.2 0.0 0.00092 18.7 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 ABK74537.1 - 0.00097 19.0 0.0 0.0056 16.5 0.0 2.0 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB BPD_transp_1 PF00528.22 ABK74538.1 - 6.9e-16 58.5 19.2 6.9e-16 58.5 19.2 2.3 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Sigma_reg_N PF13800.6 ABK74538.1 - 0.031 14.5 0.2 0.031 14.5 0.2 2.8 4 0 0 4 4 4 0 Sigma factor regulator N-terminal TssN PF17555.2 ABK74538.1 - 9.5 5.5 9.7 0.4 10.0 0.3 2.5 3 0 0 3 3 3 0 Type VI secretion system, TssN Abhydrolase_3 PF07859.13 ABK74540.1 - 3.6e-55 187.1 1.1 4.6e-55 186.7 1.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ABK74540.1 - 4.8e-11 42.2 0.3 1.4e-10 40.7 0.3 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 ABK74540.1 - 0.00018 22.2 16.0 0.00018 22.2 16.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ABK74540.1 - 0.0002 20.9 0.1 0.0043 16.5 0.3 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 ABK74540.1 - 0.00021 20.9 1.1 0.0005 19.6 1.1 1.6 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_1 PF00561.20 ABK74540.1 - 0.013 15.2 0.0 0.054 13.1 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.18 ABK74540.1 - 0.013 15.1 0.0 2.2 7.8 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Patatin PF01734.22 ABK74540.1 - 0.018 15.2 0.2 0.062 13.5 0.1 1.7 1 1 1 2 2 2 0 Patatin-like phospholipase AXE1 PF05448.12 ABK74540.1 - 0.031 12.9 0.2 0.047 12.4 0.2 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 ABK74540.1 - 0.09 12.4 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) ABC_tran PF00005.27 ABK74542.1 - 3.7e-30 105.2 0.0 5.7e-30 104.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter CysA_C_terminal PF17850.1 ABK74542.1 - 9.3e-12 45.3 0.8 9.3e-12 45.3 0.8 3.5 4 0 0 4 4 4 1 CysA C-terminal regulatory domain TOBE_2 PF08402.10 ABK74542.1 - 2.3e-08 34.1 2.2 2.6e-07 30.7 0.4 3.3 3 2 1 4 4 4 2 TOBE domain TOBE PF03459.17 ABK74542.1 - 1.4e-07 31.6 1.4 5.4e-06 26.6 0.4 2.6 2 0 0 2 2 2 1 TOBE domain AAA_21 PF13304.6 ABK74542.1 - 5.7e-07 29.6 0.4 0.0057 16.5 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system OB_MalK PF17912.1 ABK74542.1 - 4.2e-05 24.3 0.2 0.0003 21.6 0.0 2.5 2 0 0 2 2 2 1 MalK OB fold domain AAA_30 PF13604.6 ABK74542.1 - 0.0003 20.6 0.1 0.00057 19.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ABK74542.1 - 0.00092 19.5 0.0 0.0015 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 ABK74542.1 - 0.0017 18.1 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 ABK74542.1 - 0.0019 17.7 0.1 0.36 10.2 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 ABK74542.1 - 0.0043 17.0 0.1 0.0077 16.2 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 ABK74542.1 - 0.005 17.2 0.1 0.005 17.2 0.1 1.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 ABK74542.1 - 0.01 16.3 0.1 0.019 15.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 ABK74542.1 - 0.022 14.4 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_29 PF13555.6 ABK74542.1 - 0.028 14.1 0.7 0.07 12.9 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA PF00004.29 ABK74542.1 - 0.03 14.8 0.0 0.061 13.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 ABK74542.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ABK74542.1 - 0.13 12.5 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 ABK74542.1 - 0.21 11.5 0.0 0.36 10.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain Dehydratase_LU PF02286.15 ABK74545.1 - 2e-296 984.0 0.6 2.4e-296 983.7 0.6 1.0 1 0 0 1 1 1 1 Dehydratase large subunit HrcA PF01628.21 ABK74546.1 - 1e-62 211.9 1.4 1.3e-62 211.6 1.4 1.1 1 0 0 1 1 1 1 HrcA protein C terminal domain HTH_DeoR PF08220.12 ABK74546.1 - 9.2e-05 22.1 0.1 0.00091 18.9 0.0 2.7 3 0 0 3 3 3 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 ABK74546.1 - 0.00043 20.2 0.0 0.0015 18.5 0.0 1.9 2 0 0 2 2 2 1 HTH domain HrcA_DNA-bdg PF03444.15 ABK74546.1 - 0.022 14.4 0.0 0.051 13.2 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding PrmC_N PF17827.1 ABK74546.1 - 0.071 13.7 1.6 0.69 10.5 0.0 2.7 3 0 0 3 3 3 0 PrmC N-terminal domain baeRF_family10 PF18854.1 ABK74546.1 - 1.4 9.2 6.1 1 9.6 0.9 2.7 1 1 1 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 RBFA PF02033.18 ABK74547.1 - 1.6e-23 83.2 0.0 1.9e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Ribosome-binding factor A DUF1843 PF08898.10 ABK74547.1 - 0.066 13.7 1.1 0.34 11.4 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1843) SBP_bac_5 PF00496.22 ABK74548.1 - 1.2e-99 333.8 2.8 1.5e-99 333.5 2.8 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Abhydrolase_1 PF00561.20 ABK74549.1 - 9.2e-24 84.5 0.3 2.2e-22 79.9 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK74549.1 - 9.2e-24 85.3 6.7 1.1e-23 85.0 6.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK74549.1 - 4.5e-16 58.8 0.4 1e-15 57.6 0.4 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 ABK74549.1 - 0.004 16.9 0.0 0.0078 16.0 0.0 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.20 ABK74549.1 - 0.093 12.4 0.0 0.2 11.2 0.0 1.6 2 0 0 2 2 2 0 Putative esterase UPF0227 PF05728.12 ABK74549.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) LIDHydrolase PF10230.9 ABK74549.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Ndr PF03096.14 ABK74549.1 - 0.17 10.6 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Ndr family Dehydratase_MU PF02288.15 ABK74550.1 - 4.4e-27 94.1 0.0 5e-27 93.9 0.0 1.0 1 0 0 1 1 1 1 Dehydratase medium subunit SGL PF08450.12 ABK74552.1 - 3.9e-78 262.4 0.4 4.5e-78 262.2 0.4 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 ABK74552.1 - 0.00041 20.2 0.1 0.0029 17.5 0.1 2.5 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Ldl_recept_b PF00058.17 ABK74552.1 - 0.0029 18.1 0.1 0.011 16.2 0.1 2.0 2 0 0 2 2 2 1 Low-density lipoprotein receptor repeat class B Str_synth PF03088.16 ABK74552.1 - 0.013 15.7 0.0 0.039 14.1 0.0 1.8 1 0 0 1 1 1 0 Strictosidine synthase PQQ_2 PF13360.6 ABK74552.1 - 0.02 14.5 0.3 0.5 9.9 0.1 2.1 1 1 1 2 2 2 0 PQQ-like domain DUF5122 PF17164.4 ABK74552.1 - 0.025 14.9 0.2 1 9.7 0.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller Pterin_bind PF00809.22 ABK74555.1 - 5.1e-70 235.9 0.1 6.1e-70 235.7 0.1 1.1 1 0 0 1 1 1 1 Pterin binding enzyme GFO_IDH_MocA PF01408.22 ABK74556.1 - 8.6e-21 75.0 0.1 4e-20 72.8 0.1 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ABK74556.1 - 0.0071 16.4 0.0 0.014 15.4 0.0 1.6 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_2 PF03446.15 ABK74556.1 - 0.0075 16.5 0.0 0.026 14.7 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 ABK74556.1 - 0.036 14.1 0.0 0.073 13.1 0.0 1.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 ABK74556.1 - 0.075 13.6 0.0 0.18 12.4 0.0 1.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent F420H2_quin_red PF04075.14 ABK74557.1 - 3.1e-22 79.1 0.0 4e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase DUF1713 PF08213.11 ABK74558.1 - 3.6e-12 46.0 21.3 3.8e-12 45.9 21.3 1.0 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) AbiEi_1 PF09407.10 ABK74559.1 - 0.00079 19.8 0.0 0.0015 18.9 0.0 1.4 1 0 0 1 1 1 1 AbiEi antitoxin C-terminal domain Acyl-ACP_TE PF01643.17 ABK74560.1 - 9.1e-61 205.3 0.0 1e-60 205.1 0.0 1.0 1 0 0 1 1 1 1 Acyl-ACP thioesterase ScsC_N PF18312.1 ABK74560.1 - 0.13 12.1 0.1 0.26 11.1 0.1 1.5 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain Peripla_BP_2 PF01497.18 ABK74561.1 - 4.6e-21 75.5 0.2 6.2e-21 75.0 0.2 1.2 1 0 0 1 1 1 1 Periplasmic binding protein LPAM_2 PF13627.6 ABK74561.1 - 0.3 11.0 4.0 0.8 9.6 4.0 1.8 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site DUF4245 PF14030.6 ABK74562.1 - 6.2e-53 179.2 0.3 7e-53 179.0 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4245) PA26 PF04636.13 ABK74562.1 - 0.14 11.0 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) ABC_tran PF00005.27 ABK74563.1 - 4.9e-31 108.1 0.0 8.2e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK74563.1 - 2.6e-09 37.4 2.1 0.00033 20.6 0.2 2.5 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ABK74563.1 - 0.00014 21.6 0.2 0.00028 20.6 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ABK74563.1 - 0.00026 20.9 0.0 0.00043 20.2 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 ABK74563.1 - 0.00037 20.0 0.0 0.38 10.2 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA PF00004.29 ABK74563.1 - 0.00037 20.9 0.1 0.0036 17.7 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ABK74563.1 - 0.00047 20.4 1.5 0.0036 17.6 0.5 2.4 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 ABK74563.1 - 0.0011 19.3 1.0 0.0032 17.9 1.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 ABK74563.1 - 0.0013 18.4 0.1 0.0054 16.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 ABK74563.1 - 0.0041 17.1 0.0 0.0066 16.4 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain Mg_chelatase PF01078.21 ABK74563.1 - 0.0092 15.4 0.0 0.033 13.6 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 ABK74563.1 - 0.013 16.0 0.0 0.024 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 ABK74563.1 - 0.015 15.1 0.0 0.032 13.9 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 ABK74563.1 - 0.04 14.1 0.1 0.12 12.6 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ABK74563.1 - 0.044 14.0 0.0 0.23 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 ABK74563.1 - 0.12 12.4 0.8 0.2 11.6 0.2 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 ABK74563.1 - 0.14 12.1 0.2 0.79 9.6 0.1 2.2 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 ABK74563.1 - 0.14 12.7 0.1 0.85 10.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ABK74563.1 - 0.19 12.1 0.1 0.4 11.1 0.1 1.5 1 0 0 1 1 1 0 RNA helicase TetR_N PF00440.23 ABK74564.1 - 1.2e-12 47.4 0.0 7.3e-11 41.7 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory proteins, tetR family TetR_C_1 PF02909.17 ABK74564.1 - 2.6e-12 46.8 0.0 3.5e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain DUF2752 PF10825.8 ABK74565.1 - 6.8e-21 74.1 1.9 6.8e-21 74.1 1.9 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2752) Cyt_bd_oxida_II PF02322.15 ABK74565.1 - 0.0017 17.8 1.2 0.0018 17.7 1.2 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II DUF5480 PF17576.2 ABK74565.1 - 0.066 13.2 3.6 0.14 12.1 3.3 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5480) DUF4131 PF13567.6 ABK74565.1 - 0.63 9.7 6.2 1.9 8.1 2.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF1772 PF08592.11 ABK74565.1 - 0.97 9.7 7.2 0.67 10.3 4.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) Phage_holin_3_6 PF07332.11 ABK74565.1 - 10 6.2 11.3 4.2 7.4 4.9 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III SBP_bac_3 PF00497.20 ABK74566.1 - 1.6e-53 181.4 0.1 2.1e-53 181.1 0.1 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 ABK74566.1 - 6.9e-05 23.0 0.0 0.00016 21.8 0.0 1.7 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site DUF4194 PF13835.6 ABK74567.1 - 1.8e-43 148.2 3.0 2.2e-43 147.9 3.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4194) ACC_epsilon PF13822.6 ABK74568.1 - 2.2e-15 57.0 0.1 3.5e-15 56.4 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA carboxylase epsilon subunit ADH_N PF08240.12 ABK74569.1 - 3.9e-26 91.1 0.6 6e-26 90.5 0.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ABK74569.1 - 1.7e-17 63.6 0.0 2.9e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ABK74569.1 - 0.00056 21.0 0.0 0.001 20.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Peripla_BP_3 PF13377.6 ABK74570.1 - 4.9e-39 134.3 3.2 6.3e-38 130.7 0.8 2.3 2 1 0 2 2 2 1 Periplasmic binding protein-like domain LacI PF00356.21 ABK74570.1 - 4.1e-20 71.3 0.3 9.4e-19 66.9 0.1 2.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 ABK74570.1 - 1.1e-19 71.0 0.3 1.9e-19 70.2 0.2 1.4 1 1 1 2 2 2 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 ABK74570.1 - 9e-16 58.1 0.8 1.4e-15 57.5 0.8 1.3 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family HTH_3 PF01381.22 ABK74570.1 - 0.0012 18.9 0.0 0.0031 17.5 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 ABK74570.1 - 0.0034 17.7 2.5 0.008 16.5 0.2 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 ABK74570.1 - 0.028 13.8 0.8 0.1 12.0 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_38 PF13936.6 ABK74570.1 - 0.033 14.0 0.0 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.7 ABK74570.1 - 0.076 12.9 0.9 0.87 9.5 0.0 3.1 3 0 0 3 3 3 0 MarR family Amidohydro_2 PF04909.14 ABK74571.1 - 1.4e-46 159.6 2.0 1.7e-46 159.3 2.0 1.0 1 0 0 1 1 1 1 Amidohydrolase PRODH PF18327.1 ABK74571.1 - 0.13 12.5 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Proline utilization A proline dehydrogenase N-terminal domain STAS_2 PF13466.6 ABK74572.1 - 1.6e-12 47.6 0.1 2.2e-12 47.1 0.1 1.1 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 ABK74572.1 - 2.6e-11 43.2 0.0 2.7e-11 43.1 0.0 1.0 1 0 0 1 1 1 1 STAS domain BPD_transp_1 PF00528.22 ABK74573.1 - 1.7e-19 70.3 18.5 1.7e-19 70.3 18.5 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Peripla_BP_4 PF13407.6 ABK74574.1 - 5.7e-41 140.8 10.8 7.1e-41 140.5 10.8 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 ABK74574.1 - 1.5e-12 47.6 0.9 2e-12 47.2 0.9 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family SBP_bac_3 PF00497.20 ABK74574.1 - 0.0041 16.6 0.1 0.0068 15.9 0.1 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DUF2099 PF09872.9 ABK74574.1 - 0.18 11.0 0.7 3.6 6.7 0.1 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2099) FAD_binding_3 PF01494.19 ABK74575.1 - 5.2e-12 45.7 4.6 0.00021 20.7 0.1 3.1 3 0 0 3 3 3 3 FAD binding domain FAD_oxidored PF12831.7 ABK74575.1 - 1.2e-06 28.2 2.8 2.4e-06 27.2 1.3 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 ABK74575.1 - 1.3e-05 25.0 11.6 0.0021 17.7 2.5 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 ABK74575.1 - 3e-05 23.1 0.0 0.015 14.2 0.0 2.7 3 0 0 3 3 3 2 Tryptophan halogenase FAD_binding_2 PF00890.24 ABK74575.1 - 0.00028 20.1 2.3 0.00028 20.1 2.3 1.6 1 1 1 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 ABK74575.1 - 0.0003 20.1 0.9 0.0014 17.9 0.9 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ABK74575.1 - 0.001 18.2 3.9 0.0042 16.2 2.1 2.5 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 ABK74575.1 - 0.0091 15.3 0.5 0.015 14.6 0.5 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ABK74575.1 - 0.01 16.0 0.1 0.027 14.7 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ABK74575.1 - 0.016 13.9 0.4 0.021 13.5 0.4 1.1 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 ABK74575.1 - 0.022 13.9 0.1 0.022 13.9 0.1 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 ABK74575.1 - 0.046 13.0 0.1 0.07 12.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family MmgE_PrpD PF03972.14 ABK74576.1 - 1.4e-126 422.6 9.3 1.6e-126 422.4 9.3 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Pterin_bind PF00809.22 ABK74577.1 - 4.7e-85 285.1 0.2 5.4e-85 285.0 0.2 1.0 1 0 0 1 1 1 1 Pterin binding enzyme TetR_C_33 PF13305.6 ABK74577.1 - 0.75 10.6 9.9 0.18 12.5 1.7 2.9 1 1 2 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Peptidase_M24 PF00557.24 ABK74578.1 - 6.8e-63 212.1 0.4 9.1e-63 211.7 0.4 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 ABK74578.1 - 4.9e-15 56.4 0.0 1.1e-14 55.2 0.0 1.6 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain 2-Hacid_dh_C PF02826.19 ABK74579.1 - 3.3e-59 199.2 0.0 6.2e-59 198.3 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ABK74579.1 - 7.4e-26 90.4 0.0 8.5e-26 90.2 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.6 ABK74579.1 - 0.0014 19.1 0.2 0.0039 17.7 0.0 1.8 2 0 0 2 2 2 1 XdhC Rossmann domain NAD_binding_2 PF03446.15 ABK74579.1 - 0.0077 16.4 0.1 0.021 15.0 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 ABK74579.1 - 0.043 13.4 0.0 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 ABK74579.1 - 0.058 14.0 0.1 0.19 12.4 0.1 2.0 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DAGK_cat PF00781.24 ABK74580.1 - 2.1e-27 95.3 0.1 3.5e-27 94.5 0.1 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF2188 PF09954.9 ABK74580.1 - 0.0067 16.5 0.1 0.017 15.3 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2188) NAD_kinase PF01513.21 ABK74580.1 - 0.02 14.1 0.2 0.03 13.5 0.2 1.3 1 0 0 1 1 1 0 ATP-NAD kinase TP_methylase PF00590.20 ABK74580.1 - 0.057 13.3 0.2 0.086 12.8 0.2 1.3 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases Phage_holin_3_6 PF07332.11 ABK74581.1 - 2.1e-33 114.7 8.6 2.5e-33 114.5 8.6 1.1 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III Abhydrolase_9_N PF15420.6 ABK74581.1 - 0.0063 16.5 1.4 0.0073 16.3 1.4 1.1 1 0 0 1 1 1 1 Alpha/beta-hydrolase family N-terminus DUF2207 PF09972.9 ABK74581.1 - 0.023 13.5 0.5 0.026 13.3 0.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF973 PF06157.11 ABK74581.1 - 0.049 12.7 0.3 0.067 12.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF2208 PF09973.9 ABK74581.1 - 0.059 13.0 2.5 0.074 12.7 2.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) S_2TMBeta PF18153.1 ABK74581.1 - 0.28 10.9 2.2 0.35 10.6 2.2 1.2 1 0 0 1 1 1 0 SMODS-associating 2TM, beta-strand rich effector domain Ndc1_Nup PF09531.10 ABK74581.1 - 0.42 9.2 3.3 0.5 9.0 3.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup E1-E2_ATPase PF00122.20 ABK74581.1 - 0.89 9.0 3.3 1.3 8.5 3.3 1.3 1 0 0 1 1 1 0 E1-E2 ATPase Ala_racemase_N PF01168.20 ABK74582.1 - 1e-64 218.2 0.6 1.3e-64 217.9 0.6 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Ala_racemase_C PF00842.21 ABK74582.1 - 2.3e-42 143.7 0.0 4.7e-42 142.7 0.0 1.5 1 0 0 1 1 1 1 Alanine racemase, C-terminal domain Abhydrolase_6 PF12697.7 ABK74583.1 - 2.6e-22 80.5 7.8 4.3e-22 79.8 7.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK74583.1 - 7.2e-14 51.6 0.0 9.2e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ABK74583.1 - 9.7e-14 51.6 0.1 1.6e-13 50.9 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 ABK74583.1 - 0.00035 20.4 0.0 0.0007 19.4 0.0 1.5 2 0 0 2 2 2 1 PGAP1-like protein Thioesterase PF00975.20 ABK74583.1 - 0.00068 19.8 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_8 PF06259.12 ABK74583.1 - 0.011 15.4 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase Ser_hydrolase PF06821.13 ABK74583.1 - 0.025 14.4 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Esterase PF00756.20 ABK74583.1 - 0.051 13.2 0.0 0.076 12.6 0.0 1.2 1 0 0 1 1 1 0 Putative esterase NAD_binding_4 PF07993.12 ABK74583.1 - 0.18 11.0 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein RuBisCO_large_N PF02788.16 ABK74583.1 - 0.24 11.6 0.0 0.4 10.9 0.0 1.3 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain SPC25 PF06703.11 ABK74584.1 - 0.47 10.2 4.1 8.3 6.2 0.3 2.3 1 1 1 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) S_4TM PF18159.1 ABK74584.1 - 9 5.5 6.5 4.3 6.6 0.4 2.2 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain LysR_substrate PF03466.20 ABK74585.1 - 1.5e-37 129.0 4.8 1.5e-37 129.0 4.8 1.7 2 1 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 ABK74585.1 - 1e-18 67.0 1.8 1.5e-18 66.5 0.3 2.1 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family Fapy_DNA_glyco PF01149.24 ABK74586.1 - 7.9e-12 45.8 0.0 1.6e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain zf-FPG_IleRS PF06827.14 ABK74586.1 - 3.8e-09 36.2 5.1 3.8e-09 36.2 5.1 1.8 2 0 0 2 2 2 1 Zinc finger found in FPG and IleRS H2TH PF06831.14 ABK74586.1 - 1.1e-08 34.9 0.0 2.2e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Auto_anti-p27 PF06677.12 ABK74586.1 - 0.14 12.3 0.9 0.32 11.2 0.9 1.6 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) RecR PF02132.15 ABK74586.1 - 0.47 10.1 2.2 0.59 9.7 0.6 2.0 2 0 0 2 2 2 0 RecR protein HTH_Tnp_1 PF01527.20 ABK74587.1 - 4.3e-07 30.1 3.8 2e-06 28.0 3.8 2.0 1 1 0 1 1 1 1 Transposase HTH_23 PF13384.6 ABK74587.1 - 0.0028 17.4 0.4 0.0089 15.8 0.4 1.9 1 1 0 1 1 1 1 Homeodomain-like domain HMMR_N PF15905.5 ABK74587.1 - 0.015 14.8 0.2 0.024 14.1 0.1 1.4 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal HTH_28 PF13518.6 ABK74587.1 - 0.026 14.6 0.4 0.053 13.7 0.4 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_terminase PF10668.9 ABK74587.1 - 0.062 13.3 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Phage terminase small subunit MMPL PF03176.15 ABK74588.1 - 2.3e-197 654.6 44.6 9.3e-104 346.9 13.7 3.2 3 0 0 3 3 3 2 MMPL family AIP3 PF03915.13 ABK74588.1 - 0.032 13.3 3.0 0.029 13.5 1.4 1.7 2 0 0 2 2 2 0 Actin interacting protein 3 DpnII PF04556.12 ABK74588.1 - 0.048 13.0 0.0 0.083 12.2 0.0 1.4 1 0 0 1 1 1 0 DpnII restriction endonuclease PspA_IM30 PF04012.12 ABK74588.1 - 0.53 9.8 8.6 0.083 12.5 2.3 2.1 2 0 0 2 2 2 0 PspA/IM30 family IFT57 PF10498.9 ABK74588.1 - 2.8 6.8 7.6 0.18 10.7 1.3 1.8 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 TetR_N PF00440.23 ABK74589.1 - 9.1e-14 51.0 1.9 3.5e-09 36.3 0.0 2.7 3 0 0 3 3 3 2 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 ABK74589.1 - 1.8e-05 25.0 3.6 1.8e-05 25.0 3.6 2.8 3 1 0 3 3 3 1 Tetracyclin repressor-like, C-terminal domain TetR_C_7 PF14246.6 ABK74589.1 - 0.067 13.2 0.1 0.15 12.1 0.1 1.7 1 0 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal domain HTH_AsnC-type PF13404.6 ABK74589.1 - 0.53 10.2 2.6 0.62 9.9 0.6 2.2 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_31 PF13560.6 ABK74589.1 - 1.7 9.1 8.2 52 4.3 0.1 2.9 1 1 1 2 2 2 0 Helix-turn-helix domain Amidohydro_3 PF07969.11 ABK74590.1 - 2.3e-54 185.7 4.7 2.9e-54 185.3 4.7 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 ABK74590.1 - 3.6e-11 43.0 0.1 7.1e-06 25.6 0.0 2.9 2 1 0 2 2 2 2 Amidohydrolase family TPP_enzyme_N PF02776.18 ABK74591.1 - 1.2e-42 145.4 1.5 2.4e-41 141.2 0.3 2.7 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 ABK74591.1 - 9.3e-37 125.8 0.1 3.3e-36 124.0 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 ABK74591.1 - 7.7e-26 90.7 0.8 1e-24 87.1 0.2 2.6 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Beta-lactamase PF00144.24 ABK74592.1 - 3.1e-59 200.9 0.8 4.1e-59 200.5 0.8 1.1 1 0 0 1 1 1 1 Beta-lactamase Bac_luciferase PF00296.20 ABK74594.1 - 2.8e-21 76.3 1.4 5.9e-12 45.6 0.1 2.0 1 1 1 2 2 2 2 Luciferase-like monooxygenase FAD-oxidase_C PF02913.19 ABK74595.1 - 2.6e-45 155.0 0.2 3.7e-45 154.5 0.2 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 ABK74595.1 - 7.3e-34 116.5 0.8 1.5e-33 115.4 0.1 1.9 2 1 0 2 2 2 1 FAD binding domain DUF1866 PF08952.11 ABK74596.1 - 0.006 16.4 0.0 0.0061 16.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1866) LytR_cpsA_psr PF03816.14 ABK74597.1 - 4.3e-41 140.6 0.0 5.6e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Cell envelope-related transcriptional attenuator domain SMC_N PF02463.19 ABK74599.1 - 2.1e-72 243.1 0.0 2.4e-72 242.9 0.0 1.0 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 ABK74599.1 - 6.2e-20 71.7 0.0 1.8e-19 70.2 0.0 1.8 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 ABK74599.1 - 1.1e-17 64.8 0.1 8.6e-09 35.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ABK74599.1 - 7.9e-17 62.4 0.4 7.9e-17 62.4 0.4 4.2 3 1 0 3 3 3 1 AAA domain AAA_15 PF13175.6 ABK74599.1 - 8.8e-13 48.7 0.0 5e-09 36.4 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 ABK74599.1 - 6.2e-06 25.9 0.0 1.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 ABK74599.1 - 0.029 14.9 5.6 0.29 11.6 0.0 4.3 5 1 0 5 5 5 0 ABC transporter AAA_22 PF13401.6 ABK74599.1 - 0.19 12.0 5.6 3.9 7.8 0.0 4.1 4 1 1 5 5 5 0 AAA domain TetR_N PF00440.23 ABK74600.1 - 1.6e-15 56.6 0.0 1.1e-13 50.7 0.0 3.1 2 1 1 3 3 3 1 Bacterial regulatory proteins, tetR family HTH_23 PF13384.6 ABK74600.1 - 0.00028 20.6 0.0 0.00095 18.9 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_1_2 PF13022.6 ABK74600.1 - 0.00047 20.3 0.0 0.00079 19.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of insertion element transposase HTH_AraC PF00165.23 ABK74600.1 - 0.0029 17.7 0.0 0.0058 16.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_3 PF01381.22 ABK74600.1 - 0.0044 17.0 0.0 0.013 15.5 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix LacI PF00356.21 ABK74600.1 - 0.0063 16.3 1.0 0.2 11.5 0.0 2.9 3 0 0 3 3 3 1 Bacterial regulatory proteins, lacI family TetR_C_35 PF18556.1 ABK74600.1 - 0.013 15.6 0.7 0.021 14.9 0.7 1.5 1 0 0 1 1 1 0 Bacterial Tetracyclin repressor, C-terminal domain HTH_17 PF12728.7 ABK74600.1 - 0.016 15.4 0.0 0.041 14.1 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_4 PF13613.6 ABK74600.1 - 0.017 14.9 0.0 0.6 9.9 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease HTH_Tnp_1 PF01527.20 ABK74600.1 - 0.017 15.4 0.1 0.039 14.3 0.1 1.9 1 1 0 1 1 1 0 Transposase HTH_IclR PF09339.10 ABK74600.1 - 0.023 14.5 2.7 0.043 13.6 0.0 2.6 3 0 0 3 3 3 0 IclR helix-turn-helix domain HTH_28 PF13518.6 ABK74600.1 - 0.031 14.4 0.0 0.1 12.7 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_7 PF02796.15 ABK74600.1 - 0.033 14.3 0.0 0.063 13.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_31 PF13560.6 ABK74600.1 - 0.037 14.4 0.7 0.037 14.4 0.7 2.6 3 1 0 3 3 2 0 Helix-turn-helix domain Ant_C PF05586.11 ABK74600.1 - 0.093 13.3 0.0 0.2 12.3 0.0 1.5 1 0 0 1 1 1 0 Anthrax receptor C-terminus region HTH_22 PF13309.6 ABK74600.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 HTH domain Phage_AlpA PF05930.12 ABK74600.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) HTH_6 PF01418.17 ABK74600.1 - 0.16 11.9 0.0 0.41 10.7 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family Cupin_2 PF07883.11 ABK74601.1 - 6.4e-16 57.8 0.5 1.1e-15 57.0 0.5 1.4 1 0 0 1 1 1 1 Cupin domain HTH_31 PF13560.6 ABK74601.1 - 1.7e-12 47.5 0.3 2.5e-12 46.9 0.3 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 ABK74601.1 - 2.7e-10 40.1 0.1 3.9e-10 39.6 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 ABK74601.1 - 2.3e-09 37.1 0.0 3.3e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain AraC_binding PF02311.19 ABK74601.1 - 1.4e-06 28.3 1.5 2.6e-06 27.4 0.9 1.7 2 0 0 2 2 2 1 AraC-like ligand binding domain HTH_26 PF13443.6 ABK74601.1 - 5.2e-06 26.8 0.0 7.1e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain MannoseP_isomer PF01050.18 ABK74601.1 - 0.0038 17.1 0.0 0.0053 16.7 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Sigma70_r4 PF04545.16 ABK74601.1 - 0.0063 16.0 0.9 0.013 15.0 0.9 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_25 PF13413.6 ABK74601.1 - 0.018 14.9 0.2 0.035 14.0 0.2 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_37 PF13744.6 ABK74601.1 - 0.023 14.6 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain ABC2_membrane PF01061.24 ABK74602.1 - 2.1e-32 112.2 11.3 3.2e-32 111.7 11.3 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 ABK74602.1 - 1.8e-19 70.1 7.3 1.8e-19 70.1 7.3 1.9 1 1 1 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 ABK74602.1 - 1e-06 28.3 15.9 1.6e-06 27.6 15.8 1.3 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 ABK74602.1 - 0.00026 21.0 10.9 0.00052 20.0 10.5 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein PALP PF00291.25 ABK74603.1 - 1.5e-47 162.4 0.1 1.9e-47 162.1 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme HTH_AsnC-type PF13404.6 ABK74604.1 - 3.7e-29 100.3 12.6 1.7e-15 56.5 2.4 2.4 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 ABK74604.1 - 3.2e-28 97.0 0.1 8.4e-13 47.7 0.0 2.3 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding AsnC_trans_reg PF01037.21 ABK74604.1 - 1.3e-11 44.3 0.4 8.8e-05 22.4 0.1 2.5 2 0 0 2 2 2 2 Lrp/AsnC ligand binding domain MarR_2 PF12802.7 ABK74604.1 - 6.9e-07 29.1 11.3 0.0014 18.5 0.6 3.0 3 0 0 3 3 3 2 MarR family HTH_IclR PF09339.10 ABK74604.1 - 1.1e-06 28.3 7.9 0.0053 16.5 0.5 3.0 3 0 0 3 3 3 2 IclR helix-turn-helix domain MarR PF01047.22 ABK74604.1 - 4e-05 23.5 0.0 0.35 10.8 0.0 2.5 2 0 0 2 2 2 2 MarR family HTH_11 PF08279.12 ABK74604.1 - 0.00011 22.1 0.1 0.076 13.0 0.0 2.5 2 0 0 2 2 2 1 HTH domain HTH_20 PF12840.7 ABK74604.1 - 0.00026 21.0 7.1 0.011 15.8 0.4 3.3 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_28 PF13518.6 ABK74604.1 - 0.00075 19.6 5.8 0.52 10.5 0.2 3.3 2 1 1 3 3 3 2 Helix-turn-helix domain HTH_Crp_2 PF13545.6 ABK74604.1 - 0.00089 19.2 0.6 0.11 12.4 0.1 2.6 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_9 PF08221.11 ABK74604.1 - 0.0016 18.5 0.0 0.038 14.1 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TrmB PF01978.19 ABK74604.1 - 0.0031 17.3 2.2 0.061 13.2 0.0 2.7 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB Fe_dep_repress PF01325.19 ABK74604.1 - 0.0046 17.1 0.0 0.2 11.9 0.0 2.3 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain Sigma70_r4 PF04545.16 ABK74604.1 - 0.0054 16.2 0.7 0.32 10.5 0.1 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 ABK74604.1 - 0.0056 16.3 0.5 0.49 10.1 0.1 2.6 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_29 PF13551.6 ABK74604.1 - 0.0062 16.5 1.5 0.22 11.6 0.1 2.6 2 0 0 2 2 2 1 Winged helix-turn helix HTH_5 PF01022.20 ABK74604.1 - 0.0074 16.1 0.0 3.3 7.6 0.0 2.4 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family Rrf2 PF02082.20 ABK74604.1 - 0.01 16.1 0.1 7.1 7.1 0.0 2.5 2 0 0 2 2 2 0 Transcriptional regulator HTH_23 PF13384.6 ABK74604.1 - 0.016 15.0 1.5 0.74 9.7 0.1 2.6 2 0 0 2 2 2 0 Homeodomain-like domain HTH_CodY PF08222.11 ABK74604.1 - 0.018 14.6 1.1 0.34 10.5 0.3 2.7 2 0 0 2 2 2 0 CodY helix-turn-helix domain Dimerisation2 PF16864.5 ABK74604.1 - 0.019 14.9 0.9 4.7 7.3 0.0 3.2 3 0 0 3 3 3 0 Dimerisation domain dCache_3 PF14827.6 ABK74604.1 - 0.029 14.0 0.5 0.066 12.9 0.2 1.7 2 0 0 2 2 2 0 Double sensory domain of two-component sensor kinase ACT_4 PF13291.6 ABK74604.1 - 0.033 14.8 0.3 3.8 8.2 0.0 3.1 2 1 1 3 3 3 0 ACT domain DUF977 PF06163.11 ABK74604.1 - 0.12 12.3 0.9 0.36 10.8 0.2 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF977) LexA_DNA_bind PF01726.16 ABK74604.1 - 0.14 11.9 0.1 7.2 6.5 0.0 2.5 2 0 0 2 2 2 0 LexA DNA binding domain HTH_47 PF16221.5 ABK74604.1 - 0.68 9.5 3.3 16 5.1 0.0 3.2 4 0 0 4 4 4 0 winged helix-turn-helix Acyl-CoA_dh_1 PF00441.24 ABK74605.1 - 2.3e-25 89.6 7.1 3.9e-25 88.8 7.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK74605.1 - 2.7e-18 65.9 0.1 5.2e-18 65.0 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ABK74605.1 - 7.2e-10 39.5 1.6 8.8e-10 39.2 0.2 2.0 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ABK74605.1 - 2.7e-06 27.7 6.4 2.7e-06 27.7 6.4 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DUF4690 PF15756.5 ABK74605.1 - 0.064 13.9 1.2 0.21 12.2 1.2 1.9 1 0 0 1 1 1 0 Small Novel Rich in Cartilage XdhC_CoxI PF02625.16 ABK74605.1 - 2.8 8.2 8.8 0.48 10.7 1.0 3.2 2 1 1 3 3 3 0 XdhC and CoxI family HSP70 PF00012.20 ABK74606.1 - 1.5e-248 825.9 16.2 2.6e-220 732.7 8.8 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 ABK74606.1 - 9.4e-18 64.1 2.0 1.8e-17 63.1 2.0 1.5 1 0 0 1 1 1 1 MreB/Mbl protein StbA PF06406.11 ABK74606.1 - 4.4e-05 22.9 0.2 0.15 11.2 0.0 3.0 2 1 1 3 3 3 2 StbA protein FtsA PF14450.6 ABK74606.1 - 0.033 14.6 4.9 22 5.5 0.1 4.0 3 1 0 3 3 3 0 Cell division protein FtsA DUF4192 PF13830.6 ABK74606.1 - 5.6 6.9 6.6 6.3 6.8 3.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) DUF2587 PF10759.9 ABK74607.1 - 3.7e-80 267.1 1.2 4.3e-80 266.9 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2587) TetR_C_6 PF13977.6 ABK74607.1 - 0.21 11.8 3.9 0.4 10.9 3.9 1.5 1 1 0 1 1 1 0 BetI-type transcriptional repressor, C-terminal FliT PF05400.13 ABK74607.1 - 1 10.2 5.4 0.21 12.4 1.5 1.8 2 0 0 2 2 2 0 Flagellar protein FliT MFS_1 PF07690.16 ABK74608.1 - 1.1e-38 133.1 80.6 9.8e-25 87.2 48.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK74608.1 - 3.4e-14 52.6 20.1 3.4e-14 52.6 20.1 2.2 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.6 ABK74608.1 - 7.8e-11 41.2 35.8 7.8e-07 28.0 20.9 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_4 PF06779.14 ABK74608.1 - 6.2 6.0 53.1 35 3.5 53.1 2.6 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB Lant_dehydr_N PF04738.13 ABK74609.1 - 0.056 11.5 0.0 0.059 11.5 0.0 1.0 1 0 0 1 1 1 0 Lantibiotic dehydratase, N terminus Methyltransf_25 PF13649.6 ABK74610.1 - 2.5e-19 69.8 0.4 5.6e-19 68.6 0.2 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABK74610.1 - 4.9e-16 59.2 0.1 7.5e-16 58.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABK74610.1 - 5.4e-13 49.0 0.0 6.5e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK74610.1 - 5.1e-12 46.4 0.2 7.9e-12 45.8 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABK74610.1 - 2.7e-09 37.1 0.0 3.6e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 ABK74610.1 - 3.3e-08 33.2 0.0 4e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB CMAS PF02353.20 ABK74610.1 - 6.4e-08 32.2 0.0 8.5e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 ABK74610.1 - 1.9e-07 30.7 0.0 2.3e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TPMT PF05724.11 ABK74610.1 - 4.9e-07 29.6 0.0 2.4e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 ABK74610.1 - 1.5e-06 27.9 0.1 2.3e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 ABK74610.1 - 2.7e-06 27.2 0.0 3.4e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_18 PF12847.7 ABK74610.1 - 0.0004 20.3 0.2 0.00075 19.4 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 ABK74610.1 - 0.0044 16.6 0.0 0.0056 16.3 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Mur_ligase PF01225.25 ABK74610.1 - 0.054 13.8 0.0 0.13 12.6 0.0 1.7 1 1 0 1 1 1 0 Mur ligase family, catalytic domain PrmA PF06325.13 ABK74610.1 - 0.055 12.8 0.2 0.084 12.2 0.2 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 ABK74610.1 - 0.072 13.1 0.0 0.087 12.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.25 ABK74610.1 - 0.079 12.4 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase SH3_10 PF17902.1 ABK74610.1 - 0.11 12.6 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 SH3 domain DUF938 PF06080.12 ABK74610.1 - 0.16 11.7 0.0 1.4 8.6 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF938) Epimerase PF01370.21 ABK74611.1 - 5.2e-16 58.8 1.4 2.5e-13 50.0 0.8 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ABK74611.1 - 1.1e-08 35.2 5.7 2.6e-08 34.0 5.7 1.7 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 ABK74611.1 - 3e-08 33.4 0.2 5.9e-08 32.5 0.2 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ABK74611.1 - 4.9e-07 29.0 0.1 1e-06 28.0 0.1 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 ABK74611.1 - 9.5e-07 28.6 1.0 1.4e-06 28.0 1.0 1.3 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 ABK74611.1 - 2.7e-05 24.4 0.2 4.6e-05 23.7 0.2 1.4 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.25 ABK74611.1 - 3.4e-05 23.4 0.3 5.4e-05 22.7 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 ABK74611.1 - 0.0007 18.8 0.2 0.0026 16.9 0.2 1.8 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 ABK74611.1 - 0.0038 16.4 0.0 0.0056 15.9 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein KR PF08659.10 ABK74611.1 - 0.0084 16.0 1.1 0.015 15.2 1.1 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 ABK74611.1 - 0.011 16.0 0.3 0.017 15.3 0.3 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 ABK74611.1 - 0.019 14.6 0.1 0.027 14.1 0.1 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 ABK74611.1 - 0.024 15.2 0.2 0.043 14.4 0.2 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DFP PF04127.15 ABK74611.1 - 0.3 10.9 0.9 0.43 10.4 0.9 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Acyl-CoA_dh_M PF02770.19 ABK74612.1 - 5e-12 45.9 0.0 9.1e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ABK74612.1 - 7.5e-12 45.7 7.1 7.5e-12 45.7 7.1 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.24 ABK74612.1 - 2.1e-06 28.0 2.8 3.9e-06 27.1 2.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SBP56 PF05694.11 ABK74613.1 - 7.3e-193 641.5 0.0 8.1e-193 641.3 0.0 1.0 1 0 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.9 ABK74613.1 - 0.01 15.1 0.0 0.057 12.7 0.0 2.2 3 0 0 3 3 3 0 Lactonase, 7-bladed beta-propeller MgtE_N PF03448.17 ABK74614.1 - 7e-25 87.6 5.0 1.6e-24 86.5 5.0 1.6 1 0 0 1 1 1 1 MgtE intracellular N domain CBS PF00571.28 ABK74614.1 - 1.3e-11 44.7 0.1 7.6e-05 23.1 0.1 3.5 2 0 0 2 2 2 2 CBS domain FliG_M PF14841.6 ABK74614.1 - 2.5e-05 24.4 1.1 0.36 11.1 0.0 3.4 1 1 2 3 3 3 2 FliG middle domain PRC PF05239.16 ABK74614.1 - 0.00089 19.3 0.3 0.0053 16.8 0.1 2.2 2 0 0 2 2 2 1 PRC-barrel domain FliG_N PF14842.6 ABK74614.1 - 0.0094 16.5 0.2 0.31 11.6 0.1 2.5 1 1 1 2 2 2 1 FliG N-terminal domain FliG_C PF01706.16 ABK74614.1 - 0.024 14.8 0.2 0.15 12.2 0.1 2.3 2 1 0 2 2 2 0 FliG C-terminal domain HEAT_2 PF13646.6 ABK74614.1 - 0.72 10.3 6.0 22 5.5 0.1 3.6 2 1 0 2 2 2 0 HEAT repeats CMAS PF02353.20 ABK74616.1 - 4.2e-98 328.0 0.0 5.1e-98 327.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 ABK74616.1 - 2.4e-11 44.1 0.0 5.9e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABK74616.1 - 4.6e-11 42.8 0.0 8.6e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABK74616.1 - 6.2e-10 39.7 0.0 1.4e-09 38.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK74616.1 - 3.6e-06 27.6 0.0 8.1e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABK74616.1 - 0.00051 19.9 0.0 0.00076 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ABK74616.1 - 0.0054 16.3 0.0 0.0087 15.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 ABK74616.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 ABK74616.1 - 0.02 14.5 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW GCD14 PF08704.10 ABK74616.1 - 0.027 14.1 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_18 PF12847.7 ABK74616.1 - 0.04 13.8 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 ABK74616.1 - 0.078 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Aminotran_5 PF00266.19 ABK74617.1 - 1.1e-146 488.5 0.0 1.3e-146 488.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 ABK74617.1 - 1.6e-08 34.2 0.0 2.4e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ABK74617.1 - 0.00017 21.0 0.0 0.00049 19.5 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 ABK74617.1 - 0.00079 18.8 0.4 0.0016 17.8 0.4 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 ABK74617.1 - 0.0018 16.9 0.0 0.0027 16.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme MarR PF01047.22 ABK74618.1 - 4.4e-17 61.7 1.5 1.9e-16 59.7 0.5 2.3 3 0 0 3 3 3 1 MarR family MarR_2 PF12802.7 ABK74618.1 - 9.6e-12 44.6 5.7 5.8e-11 42.1 2.3 2.7 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 ABK74618.1 - 1.1e-06 29.0 1.5 2.9e-06 27.7 0.3 2.3 3 0 0 3 3 3 1 Winged helix DNA-binding domain HTH_24 PF13412.6 ABK74618.1 - 4.3e-05 23.0 1.5 6.4e-05 22.4 0.3 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 ABK74618.1 - 8.2e-05 22.4 0.1 0.00067 19.5 0.0 2.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Fe_dep_repress PF01325.19 ABK74618.1 - 0.00089 19.4 0.0 0.011 16.0 0.0 2.3 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain Rrf2 PF02082.20 ABK74618.1 - 0.015 15.6 0.3 0.21 11.9 0.1 2.5 1 1 1 2 2 2 0 Transcriptional regulator HxlR PF01638.17 ABK74618.1 - 0.073 12.9 0.3 0.26 11.2 0.1 1.9 1 1 1 2 2 2 0 HxlR-like helix-turn-helix HTH_5 PF01022.20 ABK74618.1 - 0.085 12.7 0.1 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_Crp_2 PF13545.6 ABK74618.1 - 0.092 12.7 4.5 0.17 11.9 1.3 2.5 1 1 1 2 2 2 0 Crp-like helix-turn-helix domain GntR PF00392.21 ABK74618.1 - 0.094 12.4 0.5 0.094 12.4 0.5 2.3 2 1 0 2 2 2 0 Bacterial regulatory proteins, gntR family DinB_2 PF12867.7 ABK74618.1 - 0.14 12.7 2.0 0.32 11.5 1.3 1.9 1 1 1 2 2 2 0 DinB superfamily HTH_20 PF12840.7 ABK74618.1 - 0.35 11.0 6.3 0.21 11.7 0.6 2.7 1 1 1 2 2 2 0 Helix-turn-helix domain Radical_SAM PF04055.21 ABK74619.1 - 6.6e-18 65.6 0.0 3.6e-17 63.3 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 ABK74619.1 - 3.3e-06 27.4 0.0 6.6e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 ABK74619.1 - 1.2e-05 25.4 0.0 2.5e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain SLAC1 PF03595.17 ABK74621.1 - 1.7e-14 53.8 37.8 5.4e-14 52.2 37.8 1.7 1 1 0 1 1 1 1 Voltage-dependent anion channel HTH_IclR PF09339.10 ABK74622.1 - 5.5e-14 51.7 1.1 1.3e-13 50.5 1.1 1.7 1 0 0 1 1 1 1 IclR helix-turn-helix domain IclR PF01614.18 ABK74622.1 - 2.6e-08 33.8 0.0 0.0027 17.5 0.0 2.3 2 0 0 2 2 2 2 Bacterial transcriptional regulator TrmB PF01978.19 ABK74622.1 - 6.3e-05 22.8 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 ABK74622.1 - 0.00012 22.3 0.3 0.00026 21.3 0.3 1.6 1 0 0 1 1 1 1 Transcriptional regulator HTH_24 PF13412.6 ABK74622.1 - 0.00022 20.7 0.0 0.00053 19.5 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 ABK74622.1 - 0.00037 20.3 0.9 0.0014 18.5 0.5 2.2 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 ABK74622.1 - 0.00037 20.9 0.0 0.00075 19.9 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_Crp_2 PF13545.6 ABK74622.1 - 0.0024 17.8 0.2 0.0098 15.9 0.1 2.0 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain MarR PF01047.22 ABK74622.1 - 0.004 17.1 0.0 0.0094 15.9 0.0 1.6 1 0 0 1 1 1 1 MarR family FaeA PF04703.12 ABK74622.1 - 0.027 14.8 0.1 0.077 13.4 0.0 1.7 2 0 0 2 2 2 0 FaeA-like protein HTH_5 PF01022.20 ABK74622.1 - 0.073 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family LisH_TPL PF17814.1 ABK74622.1 - 0.11 12.2 0.0 9.9 5.9 0.0 2.4 2 0 0 2 2 2 0 LisH-like dimerisation domain Fe_dep_repress PF01325.19 ABK74622.1 - 0.12 12.5 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain LacI PF00356.21 ABK74622.1 - 0.28 11.0 1.5 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family ABC_tran PF00005.27 ABK74623.1 - 1.6e-29 103.2 0.0 2.1e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK74623.1 - 1.9e-12 47.6 0.1 6.3e-05 22.9 0.3 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK74623.1 - 1.4e-06 28.0 0.1 3.8e-05 23.2 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ABK74623.1 - 6.2e-05 22.7 0.3 0.00013 21.6 0.3 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 ABK74623.1 - 0.00047 19.9 1.0 0.0072 16.1 1.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 ABK74623.1 - 0.00051 20.6 0.0 0.00077 20.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ABK74623.1 - 0.00071 19.5 0.1 0.0026 17.7 0.0 1.9 2 1 0 2 2 2 1 RsgA GTPase AAA_15 PF13175.6 ABK74623.1 - 0.0032 17.2 0.0 0.0048 16.7 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 ABK74623.1 - 0.0052 16.9 0.1 0.012 15.7 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 ABK74623.1 - 0.0089 16.4 0.0 0.014 15.8 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF2813 PF11398.8 ABK74623.1 - 0.015 14.5 0.0 0.022 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) AAA_22 PF13401.6 ABK74623.1 - 0.022 15.0 0.0 0.55 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.7 ABK74623.1 - 0.024 13.5 0.0 1.1 8.1 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain Dynamin_N PF00350.23 ABK74623.1 - 0.025 14.7 0.0 0.049 13.7 0.0 1.5 2 0 0 2 2 2 0 Dynamin family AAA_25 PF13481.6 ABK74623.1 - 0.025 14.1 0.1 0.64 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 ABK74623.1 - 0.03 13.3 0.0 0.067 12.2 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_ATPase PF09818.9 ABK74623.1 - 0.031 13.1 0.8 4.5 6.0 0.1 2.5 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_18 PF13238.6 ABK74623.1 - 0.049 14.2 0.0 0.077 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 ABK74623.1 - 0.055 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 ABK74623.1 - 0.075 13.5 0.0 2.6 8.5 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MukB PF04310.12 ABK74623.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 MukB N-terminal DUF815 PF05673.13 ABK74623.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 ABK74623.1 - 0.15 11.8 0.0 0.38 10.5 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 ABK74623.1 - 0.16 11.6 0.2 0.89 9.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain DegV PF02645.16 ABK74624.1 - 2.6e-70 237.0 0.0 2.9e-70 236.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein, DegV family COG1307 Dak1_2 PF13684.6 ABK74624.1 - 2e-07 30.4 0.1 2.6e-07 30.0 0.1 1.1 1 0 0 1 1 1 1 Dihydroxyacetone kinase family ADH_zinc_N PF00107.26 ABK74624.1 - 2.3 8.2 6.1 35 4.4 4.5 3.1 2 2 0 2 2 2 0 Zinc-binding dehydrogenase HTH_39 PF14090.6 ABK74626.1 - 0.098 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Fe_dep_repress PF01325.19 ABK74626.1 - 0.15 12.3 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain DAO PF01266.24 ABK74627.1 - 2.7e-48 165.3 5.6 3.9e-48 164.8 5.6 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 ABK74627.1 - 8.3e-31 106.5 0.1 1.5e-30 105.7 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_3 PF01494.19 ABK74627.1 - 2.7e-09 36.8 1.1 0.00028 20.2 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 ABK74627.1 - 3e-09 36.8 1.9 2.2e-06 27.3 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ABK74627.1 - 6.3e-09 35.4 11.4 0.00011 21.5 2.7 2.7 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 ABK74627.1 - 2.2e-05 23.9 0.6 0.00014 21.2 0.6 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ABK74627.1 - 0.0015 18.8 2.1 0.0042 17.3 0.7 2.7 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 ABK74627.1 - 0.0074 15.4 0.9 0.013 14.6 0.9 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 ABK74627.1 - 0.027 15.0 0.7 0.066 13.8 0.7 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 ABK74627.1 - 0.034 14.0 0.4 0.062 13.2 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ABK74627.1 - 0.046 13.0 0.1 0.11 11.8 0.1 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 ABK74627.1 - 0.11 11.7 0.3 0.27 10.5 0.3 1.5 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 ABK74627.1 - 0.2 10.3 1.5 0.32 9.6 1.5 1.3 1 0 0 1 1 1 0 HI0933-like protein Hist_deacetyl PF00850.19 ABK74628.1 - 1e-87 294.5 0.0 1.4e-87 294.0 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Acyl-CoA_dh_2 PF08028.11 ABK74629.1 - 3.2e-15 56.6 13.8 3.2e-15 56.6 13.8 2.4 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.24 ABK74629.1 - 9.8e-10 38.8 6.7 9.8e-10 38.8 6.7 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK74629.1 - 2.4e-09 37.3 0.1 1e-08 35.3 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain PIN PF01850.21 ABK74630.1 - 4.7e-16 59.4 0.0 5.2e-16 59.3 0.0 1.0 1 0 0 1 1 1 1 PIN domain Urease_alpha PF00449.20 ABK74631.1 - 1.3e-47 161.1 0.5 2.8e-47 160.0 0.5 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Amidohydro_1 PF01979.20 ABK74631.1 - 1e-44 153.3 0.2 1.3e-44 152.9 0.2 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ABK74631.1 - 5e-10 39.4 0.4 1.9e-06 27.6 0.0 2.6 2 1 0 2 2 2 2 Amidohydrolase family Mycobact_memb PF05423.13 ABK74632.1 - 1.3e-48 164.4 0.1 1.5e-48 164.3 0.1 1.0 1 0 0 1 1 1 1 Mycobacterium membrane protein NMT1_2 PF13379.6 ABK74633.1 - 5.4e-15 55.8 0.1 8.3e-15 55.2 0.1 1.3 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 ABK74633.1 - 1.6e-13 51.1 0.0 2.3e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like OpuAC PF04069.12 ABK74633.1 - 1.1e-12 48.0 0.2 1.8e-12 47.4 0.2 1.3 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system Phosphonate-bd PF12974.7 ABK74633.1 - 2.9e-07 30.4 0.1 4.3e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 ABK74633.1 - 2.6e-05 23.8 0.0 0.00017 21.1 0.0 2.0 1 1 1 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_3 PF16868.5 ABK74633.1 - 0.0033 16.9 0.0 0.005 16.3 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family MarR_2 PF12802.7 ABK74633.1 - 0.0082 16.0 0.1 0.15 11.9 0.0 2.4 2 0 0 2 2 2 1 MarR family TetR_C_14 PF17754.1 ABK74633.1 - 0.022 14.7 0.9 0.042 13.8 0.1 1.9 2 0 0 2 2 2 0 MftR C-terminal domain HTH_AsnC-type PF13404.6 ABK74633.1 - 0.028 14.3 0.2 0.16 11.8 0.1 2.2 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain CbiA PF01656.23 ABK74633.1 - 0.096 12.7 0.2 0.24 11.5 0.0 1.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain HTH_24 PF13412.6 ABK74633.1 - 0.17 11.5 0.0 0.48 10.0 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF3060 PF11259.8 ABK74634.1 - 2.1e-22 78.5 7.4 2.1e-22 78.5 7.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3060) LPAM_2 PF13627.6 ABK74634.1 - 2.4 8.1 5.4 4 7.4 5.4 1.4 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site DUF202 PF02656.15 ABK74635.1 - 1.6e-16 60.5 4.4 1.6e-16 60.5 4.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF732 PF05305.14 ABK74636.1 - 0.072 13.5 0.0 0.081 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF732) Nitroreductase PF00881.24 ABK74637.1 - 1.4e-19 70.8 0.0 1.8e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 ABK74637.1 - 0.043 13.4 0.0 0.63 9.6 0.0 2.1 2 0 0 2 2 2 0 Putative TM nitroreductase PQQ_2 PF13360.6 ABK74638.1 - 7.1e-10 38.9 2.2 2.2e-06 27.5 0.4 2.5 1 1 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 ABK74638.1 - 6.7e-08 32.1 0.9 0.022 14.7 0.0 4.5 4 0 0 4 4 4 3 PQQ enzyme repeat PQQ_3 PF13570.6 ABK74638.1 - 0.032 14.7 0.7 0.032 14.7 0.7 6.0 8 0 0 8 8 8 0 PQQ-like domain DUF998 PF06197.13 ABK74638.1 - 2.1 7.9 33.6 0.1 12.1 18.7 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF998) ABC_tran PF00005.27 ABK74639.1 - 4.7e-26 91.9 0.0 6.4e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 ABK74639.1 - 2.8e-19 69.4 0.2 8.2e-19 67.9 0.0 1.9 2 0 0 2 2 2 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 ABK74639.1 - 0.00011 22.1 0.4 0.00022 21.1 0.1 1.6 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system TniB PF05621.11 ABK74639.1 - 0.00065 19.1 0.4 0.069 12.5 0.3 2.4 2 1 0 2 2 2 1 Bacterial TniB protein AAA_22 PF13401.6 ABK74639.1 - 0.00086 19.6 1.5 0.0079 16.5 0.9 2.4 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 ABK74639.1 - 0.0019 17.6 0.1 0.0069 15.8 0.1 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 ABK74639.1 - 0.0077 16.6 1.0 0.016 15.6 1.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 ABK74639.1 - 0.02 14.3 0.0 0.052 13.0 0.0 1.6 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 ABK74639.1 - 0.053 13.3 0.5 0.41 10.4 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.6 ABK74639.1 - 0.065 12.8 1.7 1.8 8.1 0.2 2.3 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 ABK74639.1 - 0.078 13.0 0.1 0.14 12.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 ABK74639.1 - 0.18 12.2 0.6 0.77 10.2 0.6 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rhodanese PF00581.20 ABK74640.1 - 8.2e-34 116.4 0.0 7.2e-16 58.6 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain HTH_IclR PF09339.10 ABK74641.1 - 4.7e-11 42.3 0.8 4.7e-11 42.3 0.8 2.6 3 0 0 3 3 3 1 IclR helix-turn-helix domain IclR PF01614.18 ABK74641.1 - 7.2e-05 22.6 0.0 0.022 14.6 0.0 2.8 1 1 2 3 3 3 2 Bacterial transcriptional regulator HTH_23 PF13384.6 ABK74641.1 - 0.0016 18.2 0.1 0.0066 16.2 0.1 2.1 2 1 1 3 3 3 1 Homeodomain-like domain MarR_2 PF12802.7 ABK74641.1 - 0.023 14.6 1.3 0.1 12.5 0.2 2.6 3 1 1 4 4 4 0 MarR family Rrf2 PF02082.20 ABK74641.1 - 0.063 13.6 0.1 0.14 12.5 0.1 1.6 1 0 0 1 1 1 0 Transcriptional regulator HTH_Crp_2 PF13545.6 ABK74641.1 - 0.064 13.2 0.2 0.44 10.6 0.1 2.3 1 1 1 2 2 2 0 Crp-like helix-turn-helix domain DUF4423 PF14394.6 ABK74641.1 - 0.18 11.5 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) Aminotran_5 PF00266.19 ABK74642.1 - 5.9e-66 222.9 0.5 7.2e-66 222.6 0.5 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 ABK74642.1 - 3.1e-09 36.5 0.5 3.8e-09 36.2 0.5 1.3 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 ABK74642.1 - 0.0046 16.3 0.7 0.0066 15.8 0.7 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF3341 PF11821.8 ABK74643.1 - 3.2 7.4 11.3 0.065 12.9 2.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3341) IclR PF01614.18 ABK74644.1 - 4.7e-29 100.8 0.0 7e-29 100.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 ABK74644.1 - 8.1e-15 54.4 0.9 8.1e-15 54.4 0.9 2.3 3 0 0 3 3 3 1 IclR helix-turn-helix domain DUF4423 PF14394.6 ABK74644.1 - 0.046 13.4 0.0 0.072 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) HTH_20 PF12840.7 ABK74644.1 - 0.66 10.1 4.1 0.59 10.2 0.2 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain rve PF00665.26 ABK74645.1 - 3.1e-21 75.8 0.0 5.4e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 ABK74645.1 - 7.4e-17 60.9 0.0 1.6e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 ABK74645.1 - 2e-12 47.1 1.1 8.4e-12 45.0 1.6 1.8 2 0 0 2 2 2 1 HTH-like domain rve_2 PF13333.6 ABK74645.1 - 3.1e-07 30.4 0.3 1e-06 28.8 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Amidase PF01425.21 ABK74646.1 - 4.8e-154 513.6 1.2 5.4e-154 513.5 1.2 1.0 1 0 0 1 1 1 1 Amidase PDH PF02153.17 ABK74646.1 - 0.15 11.0 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase ABC_tran PF00005.27 ABK74647.1 - 1.6e-28 99.9 0.0 2.1e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK74647.1 - 5.4e-06 26.4 4.2 0.0077 16.1 0.2 2.3 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ABK74647.1 - 0.00074 19.2 0.1 0.0016 18.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 ABK74647.1 - 0.0077 16.8 0.1 0.012 16.2 0.1 1.2 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 ABK74647.1 - 0.028 13.9 0.0 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 ABK74647.1 - 0.092 12.5 0.5 0.87 9.3 0.5 2.2 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ABK74647.1 - 0.092 13.1 1.2 0.32 11.4 1.0 1.9 1 1 1 2 2 2 0 AAA ATPase domain SbcCD_C PF13558.6 ABK74647.1 - 0.1 12.9 0.1 0.22 11.8 0.1 1.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Complex1_51K PF01512.17 ABK74648.1 - 2.7e-45 154.0 0.0 3.8e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 ABK74648.1 - 1.6e-30 105.0 0.3 2.7e-30 104.3 0.3 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 ABK74648.1 - 0.00063 19.6 1.7 0.0016 18.2 1.7 1.7 1 0 0 1 1 1 1 SLBB domain Dioxygenase_C PF00775.21 ABK74649.1 - 7.9e-46 155.8 0.0 1e-45 155.4 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 ABK74649.1 - 4.3e-31 106.6 0.1 8.8e-31 105.6 0.1 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 ABK74649.1 - 5.6e-07 29.8 0.3 3.7e-06 27.1 0.1 2.3 2 1 0 2 2 2 1 Carboxypeptidase regulatory-like domain SpaA PF17802.1 ABK74649.1 - 0.021 15.1 0.0 0.041 14.2 0.0 1.4 1 0 0 1 1 1 0 Prealbumin-like fold domain CarbopepD_reg_2 PF13715.6 ABK74649.1 - 0.096 12.7 0.0 10 6.2 0.0 2.5 2 0 0 2 2 2 0 CarboxypepD_reg-like domain DUF824 PF05688.11 ABK74649.1 - 0.11 12.3 0.0 0.54 10.1 0.0 2.1 2 0 0 2 2 2 0 Salmonella repeat of unknown function (DUF824) DUF4198 PF10670.9 ABK74649.1 - 0.12 12.8 0.2 0.18 12.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) SdrD_B PF17210.3 ABK74649.1 - 0.17 12.1 0.0 0.46 10.7 0.0 1.7 2 0 0 2 2 2 0 SdrD B-like domain DUF1707 PF08044.11 ABK74651.1 - 1.2e-19 70.1 2.6 2e-19 69.4 2.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1707) T_cell_tran_alt PF15128.6 ABK74651.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 T-cell leukemia translocation-altered DDE_Tnp_1 PF01609.21 ABK74652.1 - 1.9e-13 50.5 0.0 6.9e-13 48.7 0.0 1.8 1 1 0 1 1 1 1 Transposase DDE domain RDD PF06271.12 ABK74653.1 - 4.8e-09 36.5 12.3 9e-09 35.7 12.3 1.4 1 1 0 1 1 1 1 RDD family BKACE PF05853.12 ABK74654.1 - 2.7e-95 318.8 0.1 3e-95 318.6 0.1 1.0 1 0 0 1 1 1 1 beta-keto acid cleavage enzyme SATase_N PF06426.14 ABK74654.1 - 0.036 14.4 0.0 0.073 13.5 0.0 1.5 1 0 0 1 1 1 0 Serine acetyltransferase, N-terminal Amidohydro_1 PF01979.20 ABK74655.1 - 4.5e-49 167.6 2.4 5.4e-49 167.4 2.4 1.1 1 0 0 1 1 1 1 Amidohydrolase family MMPL PF03176.15 ABK74656.1 - 5e-75 252.5 10.1 4.3e-40 137.7 5.3 2.3 2 0 0 2 2 2 2 MMPL family DUF4148 PF13663.6 ABK74656.1 - 0.12 12.6 0.2 0.12 12.6 0.2 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) Ald_Xan_dh_C2 PF02738.18 ABK74659.1 - 6.2e-152 506.9 1.0 8.2e-152 506.5 1.0 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 ABK74659.1 - 8e-23 80.9 0.8 4.9e-22 78.4 0.8 2.3 1 1 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Acyl-CoA_dh_N PF02771.16 ABK74660.1 - 0.0011 19.6 0.0 0.0013 19.3 0.0 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain NAD_binding_10 PF13460.6 ABK74661.1 - 1.5e-21 77.2 0.2 2.3e-21 76.5 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ABK74661.1 - 1.5e-17 63.9 0.0 2.2e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 ABK74661.1 - 3.2e-11 43.2 1.1 1.1e-10 41.5 1.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ABK74661.1 - 1.5e-08 34.1 0.1 2.2e-05 23.7 0.1 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain 3Beta_HSD PF01073.19 ABK74661.1 - 8.3e-05 21.7 0.1 0.00016 20.8 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ABK74661.1 - 0.023 14.1 0.1 0.071 12.5 0.1 1.8 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 ABK74661.1 - 0.043 13.3 0.3 0.11 12.0 0.3 1.8 1 1 0 1 1 1 0 short chain dehydrogenase Polysacc_synt_2 PF02719.15 ABK74661.1 - 0.057 12.5 0.5 1.4 8.0 0.6 2.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Dak1_2 PF13684.6 ABK74662.1 - 2.2e-72 243.8 0.0 3.1e-72 243.3 0.0 1.2 1 0 0 1 1 1 1 Dihydroxyacetone kinase family Dak2 PF02734.17 ABK74662.1 - 1.9e-33 115.8 12.5 1.9e-33 115.8 12.5 2.0 2 0 0 2 2 2 1 DAK2 domain DUF3592 PF12158.8 ABK74663.1 - 0.013 15.6 3.4 0.039 14.0 3.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3592) Tad PF13400.6 ABK74663.1 - 2.5 8.5 10.9 0.17 12.2 2.9 2.7 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like Cyanate_lyase PF02560.14 ABK74664.1 - 1.1e-33 114.9 0.0 1.5e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain ThiS PF02597.20 ABK74666.1 - 1.2e-09 38.7 0.1 1.4e-09 38.4 0.1 1.1 1 0 0 1 1 1 1 ThiS family ThiS-like PF14453.6 ABK74666.1 - 0.047 13.7 0.0 0.16 12.0 0.0 1.8 2 0 0 2 2 2 0 ThiS-like ubiquitin AMP-binding PF00501.28 ABK74667.1 - 3.4e-47 161.0 0.9 3.7e-40 137.8 0.0 2.3 1 1 1 2 2 2 2 AMP-binding enzyme Acyl_transf_3 PF01757.22 ABK74667.1 - 6.1e-06 25.5 21.0 8.3e-05 21.8 21.0 2.2 1 1 0 1 1 1 1 Acyltransferase family PP-binding PF00550.25 ABK74667.1 - 5.2e-05 23.5 0.1 0.00015 22.0 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Gemini_mov PF01708.16 ABK74667.1 - 0.008 15.9 0.0 0.026 14.3 0.0 1.8 1 0 0 1 1 1 1 Geminivirus putative movement protein DUF1480 PF07351.13 ABK74667.1 - 0.19 12.0 0.0 0.53 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1480) VPDSG-CTERM PF18205.1 ABK74668.1 - 0.054 13.3 0.4 0.054 13.3 0.4 2.9 3 0 0 3 3 3 0 VPDSG-CTERM motif Usp PF00582.26 ABK74669.1 - 2.7e-25 89.5 2.8 2e-12 47.8 1.2 2.1 2 0 0 2 2 2 2 Universal stress protein family Ribonuc_L-PSP PF01042.21 ABK74670.1 - 3.9e-17 62.4 0.0 4.6e-17 62.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP NAPRTase PF04095.16 ABK74670.1 - 0.069 12.8 0.0 0.072 12.7 0.0 1.1 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) family DUF1952 PF09189.10 ABK74670.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1952) Haem_degrading PF03928.14 ABK74671.1 - 1.8e-27 95.7 0.1 2.1e-27 95.6 0.1 1.0 1 0 0 1 1 1 1 Haem-degrading MreB_Mbl PF06723.13 ABK74672.1 - 0.02 13.7 0.7 0.15 10.9 0.1 2.1 1 1 1 2 2 2 0 MreB/Mbl protein Shisa PF13908.6 ABK74672.1 - 0.31 11.3 2.7 0.59 10.4 2.7 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator SKA2 PF16740.5 ABK74673.1 - 0.069 12.9 0.3 0.097 12.5 0.3 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 DoxX PF07681.12 ABK74674.1 - 7.5e-09 36.1 0.2 1.6e-08 35.0 0.2 1.5 1 0 0 1 1 1 1 DoxX LEA_4 PF02987.16 ABK74674.1 - 0.0097 16.0 0.3 8.1 6.6 0.0 2.7 3 0 0 3 3 3 2 Late embryogenesis abundant protein Collagen_mid PF15984.5 ABK74674.1 - 0.018 14.8 0.7 0.035 13.9 0.7 1.4 1 0 0 1 1 1 0 Bacterial collagen, middle region DUF883 PF05957.13 ABK74674.1 - 0.13 12.9 17.9 0.52 10.9 5.8 2.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) SURF4 PF02077.15 ABK74674.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 SURF4 family DUF1318 PF07027.12 ABK74674.1 - 0.43 11.0 4.2 1.9 9.0 0.5 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1318) Na_H_Exchanger PF00999.21 ABK74675.1 - 2.1e-38 132.1 39.0 2.6e-38 131.8 39.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PRA1 PF03208.19 ABK74675.1 - 6.2 6.4 14.4 3.3 7.3 6.1 2.7 2 0 0 2 2 2 0 PRA1 family protein Rrf2 PF02082.20 ABK74676.1 - 1e-15 57.8 0.8 1.4e-15 57.4 0.8 1.2 1 0 0 1 1 1 1 Transcriptional regulator HTH_27 PF13463.6 ABK74676.1 - 6.7e-05 23.3 0.3 0.00012 22.5 0.3 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.19 ABK74676.1 - 0.00024 20.9 0.0 0.00039 20.2 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Rio2_N PF09202.11 ABK74676.1 - 0.0074 16.5 0.0 0.011 16.0 0.0 1.2 1 0 0 1 1 1 1 Rio2, N-terminal HTH_Crp_2 PF13545.6 ABK74676.1 - 0.011 15.7 0.3 0.027 14.5 0.3 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Phage_rep_O PF04492.13 ABK74676.1 - 0.016 15.8 0.0 0.025 15.2 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage replication protein O DUF4423 PF14394.6 ABK74676.1 - 0.038 13.7 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) GntR PF00392.21 ABK74676.1 - 0.073 12.7 0.3 0.073 12.7 0.3 1.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family Fe_dep_repress PF01325.19 ABK74676.1 - 0.1 12.8 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain MarR PF01047.22 ABK74676.1 - 0.13 12.2 0.1 0.66 10.0 0.1 2.0 2 0 0 2 2 2 0 MarR family BPD_transp_1 PF00528.22 ABK74677.1 - 1.8e-43 148.4 12.9 1.8e-43 148.4 12.9 2.2 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Aminotran_4 PF01063.19 ABK74679.1 - 1.8e-33 116.3 0.0 2.3e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV MDMPI_N PF11716.8 ABK74680.1 - 8.6e-13 49.2 7.0 4.3e-09 37.2 0.1 3.2 3 0 0 3 3 3 3 Mycothiol maleylpyruvate isomerase N-terminal domain DinB_2 PF12867.7 ABK74680.1 - 0.027 15.0 0.0 0.066 13.7 0.0 1.8 1 1 1 2 2 2 0 DinB superfamily MDMPI_C PF07398.11 ABK74680.1 - 1.1 10.1 15.9 1e+02 3.9 15.6 2.9 1 1 1 2 2 2 0 MDMPI C-terminal domain HPPK PF01288.20 ABK74682.1 - 2e-29 102.3 0.0 2.9e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) MFS_1 PF07690.16 ABK74683.1 - 2.7e-39 135.1 53.2 2.7e-36 125.2 41.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ABK74683.1 - 2e-07 30.7 40.5 5.5e-07 29.2 38.2 2.2 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB SIS PF01380.22 ABK74684.1 - 1.2e-09 38.1 0.5 4.4e-08 33.0 0.0 2.5 2 0 0 2 2 2 1 SIS domain SIS_2 PF13580.6 ABK74684.1 - 4.1e-06 26.8 1.8 9.1e-06 25.7 0.2 2.3 2 1 0 2 2 2 1 SIS domain UBA_4 PF14555.6 ABK74684.1 - 0.00041 20.1 0.3 0.36 10.7 0.1 2.5 1 1 1 2 2 2 2 UBA-like domain ANTAR PF03861.14 ABK74684.1 - 0.073 12.9 0.9 1.8 8.5 0.1 2.5 2 0 0 2 2 2 0 ANTAR domain PrsW-protease PF13367.6 ABK74685.1 - 5.4e-36 123.9 7.3 5.4e-36 123.9 7.3 1.8 2 0 0 2 2 2 1 PrsW family intramembrane metalloprotease GerE PF00196.19 ABK74686.1 - 9.4e-14 50.7 0.0 2e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family AAA_16 PF13191.6 ABK74686.1 - 2.9e-09 37.5 0.2 2.9e-09 37.5 0.2 3.6 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 ABK74686.1 - 1.6e-07 31.7 0.0 4.2e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 ABK74686.1 - 3.2e-05 23.7 0.0 9e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.12 ABK74686.1 - 6.3e-05 23.0 0.1 0.00014 21.8 0.1 1.7 1 1 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 ABK74686.1 - 0.00028 20.7 0.2 0.00028 20.7 0.2 3.0 3 1 0 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 ABK74686.1 - 0.00056 19.9 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 ABK74686.1 - 0.00059 20.3 0.0 0.0013 19.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 ABK74686.1 - 0.00081 19.4 0.0 0.0025 17.8 0.0 1.6 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea HTH_23 PF13384.6 ABK74686.1 - 0.0012 18.6 0.0 0.0041 16.9 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain AAA_33 PF13671.6 ABK74686.1 - 0.0027 17.8 0.4 0.099 12.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ABK74686.1 - 0.0048 16.9 0.2 0.013 15.5 0.1 1.8 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 ABK74686.1 - 0.0092 16.5 0.0 0.023 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 ABK74686.1 - 0.01 16.4 0.0 0.022 15.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter TsaE PF02367.17 ABK74686.1 - 0.026 14.5 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 ABK74686.1 - 0.029 14.6 0.0 0.091 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 ABK74686.1 - 0.035 13.3 0.1 0.058 12.6 0.1 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_7 PF12775.7 ABK74686.1 - 0.037 13.5 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RuvB_N PF05496.12 ABK74686.1 - 0.041 13.6 0.0 0.098 12.4 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 ABK74686.1 - 0.041 13.3 0.1 1.4 8.2 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma70_r4_2 PF08281.12 ABK74686.1 - 0.045 13.4 0.2 0.23 11.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 APS_kinase PF01583.20 ABK74686.1 - 0.076 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase HTH_38 PF13936.6 ABK74686.1 - 0.079 12.7 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain NTPase_1 PF03266.15 ABK74686.1 - 0.08 12.9 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 NTPase PhoH PF02562.16 ABK74686.1 - 0.11 11.9 0.1 0.31 10.5 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.6 ABK74686.1 - 0.16 12.3 5.5 0.56 10.5 2.1 2.9 2 1 0 2 2 2 0 AAA domain TPR_19 PF14559.6 ABK74686.1 - 0.17 12.4 0.1 0.17 12.4 0.1 4.3 3 1 2 5 5 5 0 Tetratricopeptide repeat RNA_helicase PF00910.22 ABK74686.1 - 0.25 11.8 0.0 0.44 11.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase UPF0051 PF01458.17 ABK74687.1 - 3.8e-76 255.6 0.1 5e-76 255.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) DDE_3 PF13358.6 ABK74688.1 - 3e-24 85.4 0.0 4.5e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 ABK74688.1 - 4e-15 56.2 6.4 1.6e-14 54.3 0.7 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.6 ABK74688.1 - 9e-14 51.2 3.6 3.2e-13 49.5 0.4 3.2 3 0 0 3 3 3 1 Winged helix-turn helix HTH_28 PF13518.6 ABK74688.1 - 1.5e-13 50.6 5.9 3.5e-11 43.1 0.4 3.1 3 0 0 3 3 2 2 Helix-turn-helix domain HTH_23 PF13384.6 ABK74688.1 - 1.5e-12 46.9 1.7 3.6e-09 36.1 0.4 3.2 2 1 1 3 3 3 2 Homeodomain-like domain HTH_50 PF18024.1 ABK74688.1 - 0.00034 20.2 0.2 0.0013 18.3 0.0 2.1 3 0 0 3 3 2 1 Helix-turn-helix domain HTH_24 PF13412.6 ABK74688.1 - 0.00071 19.1 0.1 0.039 13.5 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_6 PF01418.17 ABK74688.1 - 0.001 19.0 0.0 0.0036 17.2 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain, rpiR family HTH_IclR PF09339.10 ABK74688.1 - 0.0015 18.3 0.6 0.059 13.2 0.0 2.4 2 0 0 2 2 2 1 IclR helix-turn-helix domain YdaS_antitoxin PF15943.5 ABK74688.1 - 0.003 17.4 0.2 0.9 9.5 0.0 2.9 3 0 0 3 3 3 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Sigma70_r4_2 PF08281.12 ABK74688.1 - 0.0046 16.6 0.0 0.051 13.3 0.0 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_26 PF13443.6 ABK74688.1 - 0.0058 17.0 0.6 0.99 9.9 0.0 3.1 3 0 0 3 3 3 1 Cro/C1-type HTH DNA-binding domain HTH_Crp_2 PF13545.6 ABK74688.1 - 0.0068 16.4 0.1 2.6 8.1 0.0 2.5 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_AsnC-type PF13404.6 ABK74688.1 - 0.0089 15.8 0.1 0.64 9.9 0.0 2.5 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_37 PF13744.6 ABK74688.1 - 0.026 14.5 0.0 0.47 10.5 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.7 ABK74688.1 - 0.034 14.3 0.4 3.3 8.0 0.0 3.1 3 0 0 3 3 2 0 Helix-turn-helix domain MarR PF01047.22 ABK74688.1 - 0.044 13.7 0.0 12 5.9 0.0 2.5 2 0 0 2 2 2 0 MarR family HTH_36 PF13730.6 ABK74688.1 - 0.044 13.7 0.0 0.34 10.9 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 ABK74688.1 - 0.048 14.2 1.5 0.056 14.0 0.1 1.8 2 0 0 2 2 1 0 leucine-zipper of insertion element IS481 HTH_Tnp_ISL3 PF13542.6 ABK74688.1 - 0.049 13.0 4.2 0.054 12.9 0.7 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4 PF04545.16 ABK74688.1 - 0.056 13.0 0.1 3.2 7.3 0.0 2.7 2 0 0 2 2 2 0 Sigma-70, region 4 GerE PF00196.19 ABK74688.1 - 0.084 12.4 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family DUF746 PF05344.11 ABK74688.1 - 0.13 12.1 0.8 2.5 8.0 0.0 3.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF746) HTH_3 PF01381.22 ABK74688.1 - 0.18 11.9 0.0 14 5.9 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix DUF58 PF01882.18 ABK74689.1 - 7.2e-16 58.3 0.1 2.1e-15 56.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function DUF58 DUF2161 PF09929.9 ABK74690.1 - 0.11 12.6 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Putative PD-(D/E)XK phosphodiesterase (DUF2161) SIR2_2 PF13289.6 ABK74691.1 - 2.4e-26 92.6 0.0 1.9e-25 89.6 0.0 2.4 3 0 0 3 3 3 1 SIR2-like domain AAA_2 PF07724.14 ABK74692.1 - 3.1e-52 177.1 0.0 2.1e-50 171.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 ABK74692.1 - 6.1e-35 119.3 2.2 1.7e-34 117.8 2.2 1.8 1 0 0 1 1 1 1 AAA lid domain Clp_N PF02861.20 ABK74692.1 - 1e-34 118.4 7.2 8.9e-18 64.2 0.6 2.8 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component ClpB_D2-small PF10431.9 ABK74692.1 - 2.1e-25 88.6 0.5 7.9e-25 86.7 0.5 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 ABK74692.1 - 5.9e-22 78.5 0.0 6.6e-12 46.0 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ABK74692.1 - 4e-17 62.5 0.0 1e-10 41.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ABK74692.1 - 1.2e-12 48.6 3.1 2e-06 28.3 0.1 4.1 2 1 2 4 4 4 2 AAA ATPase domain Sigma54_activat PF00158.26 ABK74692.1 - 2.4e-10 40.3 0.1 2.3e-07 30.6 0.0 2.6 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 ABK74692.1 - 1.3e-08 35.2 0.3 0.0033 17.7 0.1 4.5 3 2 1 4 4 3 2 AAA domain TniB PF05621.11 ABK74692.1 - 9.8e-08 31.6 0.0 0.00011 21.6 0.0 4.0 2 2 1 3 3 3 1 Bacterial TniB protein UVR PF02151.19 ABK74692.1 - 8.4e-07 28.5 8.4 2.4e-06 27.1 8.4 1.9 1 0 0 1 1 1 1 UvrB/uvrC motif ATPase_2 PF01637.18 ABK74692.1 - 1.4e-06 28.4 2.3 0.038 13.9 0.1 4.1 3 2 1 4 4 3 2 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 ABK74692.1 - 1.1e-05 25.2 0.0 0.093 12.5 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 ABK74692.1 - 4.2e-05 24.1 2.9 0.19 12.3 0.0 3.8 4 0 0 4 4 4 2 AAA domain RsgA_GTPase PF03193.16 ABK74692.1 - 0.0001 22.3 0.1 0.37 10.7 0.0 2.6 2 1 0 2 2 2 2 RsgA GTPase RuvB_N PF05496.12 ABK74692.1 - 0.00011 22.0 0.2 2.1 8.1 0.0 4.4 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 ABK74692.1 - 0.00026 21.3 0.0 1 9.8 0.0 2.8 2 0 0 2 2 2 2 RNA helicase TsaE PF02367.17 ABK74692.1 - 0.00026 21.0 0.0 0.28 11.2 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 ABK74692.1 - 0.00035 20.3 0.0 0.23 11.2 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 ABK74692.1 - 0.00051 20.2 0.1 2.2 8.4 0.0 3.6 4 0 0 4 4 3 1 AAA domain DUF815 PF05673.13 ABK74692.1 - 0.00076 18.7 0.1 2.2 7.4 0.0 3.6 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_3 PF07726.11 ABK74692.1 - 0.00081 19.3 0.0 0.56 10.1 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 ABK74692.1 - 0.0013 18.1 0.0 5.7 6.3 0.0 3.4 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI DNA_pol3_delta2 PF13177.6 ABK74692.1 - 0.0017 18.2 0.0 2.2 8.0 0.0 2.7 3 0 0 3 3 2 1 DNA polymerase III, delta subunit AAA_28 PF13521.6 ABK74692.1 - 0.0022 18.3 1.1 5.5 7.2 0.0 3.6 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 ABK74692.1 - 0.0025 17.8 0.0 0.11 12.4 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.6 ABK74692.1 - 0.0082 15.9 0.0 2.4 8.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Roc PF08477.13 ABK74692.1 - 0.0083 16.3 0.0 4.5 7.5 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ResIII PF04851.15 ABK74692.1 - 0.011 15.8 0.0 6.3 6.8 0.0 4.0 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 ABK74692.1 - 0.012 15.2 0.0 1.9 8.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 ABK74692.1 - 0.018 14.6 0.0 2.8 7.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 ABK74692.1 - 0.021 15.4 7.1 0.23 11.9 0.1 3.3 2 2 0 2 2 2 0 AAA domain DUF99 PF01949.16 ABK74692.1 - 0.022 14.2 0.0 2.8 7.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF99 Torsin PF06309.11 ABK74692.1 - 0.022 14.9 0.0 0.39 10.8 0.0 2.7 3 0 0 3 3 3 0 Torsin AAA_19 PF13245.6 ABK74692.1 - 0.027 14.8 0.4 0.78 10.1 0.2 3.3 3 1 0 3 3 2 0 AAA domain Zeta_toxin PF06414.12 ABK74692.1 - 0.028 13.7 0.3 2.9 7.1 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin AAA_30 PF13604.6 ABK74692.1 - 0.028 14.1 0.0 2.6 7.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 ABK74692.1 - 0.05 13.5 0.1 8.7 6.2 0.0 3.1 3 0 0 3 3 2 0 NTPase ABC_tran PF00005.27 ABK74692.1 - 0.077 13.5 0.0 6.5 7.3 0.0 2.7 2 0 0 2 2 2 0 ABC transporter CbiA PF01656.23 ABK74692.1 - 0.16 12.0 0.1 15 5.7 0.1 3.1 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain PEPCK_ATP PF01293.20 ABK74692.1 - 0.16 10.6 0.0 0.31 9.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase PQQ_2 PF13360.6 ABK74693.1 - 0.00041 20.0 4.4 0.0011 18.6 0.4 2.3 2 0 0 2 2 2 2 PQQ-like domain TetR_N PF00440.23 ABK74694.1 - 1.5e-07 31.1 0.3 3e-07 30.1 0.3 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_30 PF17939.1 ABK74694.1 - 9.9e-07 29.0 1.0 2e-06 28.0 0.1 1.9 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TniQ PF06527.11 ABK74695.1 - 1.3e-05 26.0 3.9 3.4e-05 24.6 3.9 1.8 1 1 0 1 1 1 1 TniQ GATase_5 PF13507.6 ABK74696.1 - 6.7e-36 123.7 0.0 1.8e-35 122.3 0.0 1.6 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase_3 PF07685.14 ABK74696.1 - 6.2e-08 32.5 0.0 1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 ABK74696.1 - 5.6e-07 29.5 0.1 8.4e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 ABK74696.1 - 2.4e-06 27.5 0.1 4.7e-06 26.5 0.1 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 ABK74696.1 - 0.0016 18.3 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 SNO glutamine amidotransferase family Peptidase_C26 PF07722.13 ABK74696.1 - 0.0018 18.1 0.3 0.0056 16.5 0.1 1.8 2 0 0 2 2 2 1 Peptidase C26 GFO_IDH_MocA PF01408.22 ABK74698.1 - 2.2e-18 67.2 1.0 3.3e-18 66.6 0.3 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ABK74698.1 - 2.9e-09 36.9 0.0 6.6e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_2 PF03446.15 ABK74698.1 - 0.035 14.3 0.0 0.054 13.7 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ABK74698.1 - 0.083 13.5 0.1 0.19 12.3 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 ABK74698.1 - 0.086 12.2 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Peripla_BP_4 PF13407.6 ABK74698.1 - 0.1 12.2 0.9 5.7 6.4 0.5 3.1 2 2 2 4 4 4 0 Periplasmic binding protein domain TrkA_N PF02254.18 ABK74698.1 - 0.1 12.9 0.3 0.26 11.6 0.3 1.7 1 0 0 1 1 1 0 TrkA-N domain SH3_4 PF06347.13 ABK74698.1 - 0.28 11.0 3.1 3.9 7.4 0.2 3.3 3 0 0 3 3 3 0 Bacterial SH3 domain Rieske PF00355.26 ABK74699.1 - 5.2e-22 77.6 0.0 9.2e-22 76.8 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ring_hydroxyl_A PF00848.19 ABK74699.1 - 2.9e-15 56.8 0.3 4.8e-15 56.1 0.3 1.2 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) BPL_LplA_LipB PF03099.19 ABK74700.1 - 1.5e-09 37.8 0.0 2.3e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 ABK74700.1 - 5.6e-08 32.6 0.5 5.6e-08 32.6 0.5 1.9 2 0 0 2 2 2 1 Biotin protein ligase C terminal domain Epimerase PF01370.21 ABK74701.1 - 2.3e-20 73.1 0.0 3.3e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ABK74701.1 - 5e-15 55.3 0.0 6.3e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 ABK74701.1 - 6.6e-12 45.7 0.0 9e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 ABK74701.1 - 3.3e-09 36.6 0.0 5.6e-09 35.9 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ABK74701.1 - 2.1e-07 30.4 0.1 1.9e-06 27.2 0.1 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 ABK74701.1 - 5.8e-07 28.9 0.0 1.1e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein KR PF08659.10 ABK74701.1 - 0.00044 20.2 0.3 0.031 14.2 0.3 2.5 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 ABK74701.1 - 0.002 17.6 0.1 0.0049 16.4 0.0 1.8 2 1 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 ABK74701.1 - 0.011 15.4 0.0 0.016 14.8 0.0 1.3 1 1 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.17 ABK74701.1 - 0.029 13.5 0.0 0.052 12.7 0.0 1.3 1 1 0 1 1 1 0 RmlD substrate binding domain adh_short_C2 PF13561.6 ABK74702.1 - 2.3e-58 197.6 9.9 2.6e-58 197.4 9.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK74702.1 - 1.4e-51 174.8 3.9 1.8e-51 174.4 3.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK74702.1 - 3e-15 56.6 3.9 4.8e-15 55.9 3.9 1.2 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 ABK74702.1 - 0.018 15.1 0.4 0.038 14.1 0.4 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Amidohydro_2 PF04909.14 ABK74702.1 - 0.02 14.7 0.2 0.026 14.3 0.2 1.2 1 0 0 1 1 1 0 Amidohydrolase Methyltransf_16 PF10294.9 ABK74702.1 - 0.035 13.8 0.1 0.099 12.4 0.1 1.7 2 0 0 2 2 2 0 Lysine methyltransferase 3HCDH_N PF02737.18 ABK74702.1 - 0.064 13.1 4.2 0.082 12.8 2.4 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_11 PF08241.12 ABK74702.1 - 0.12 13.0 0.5 0.3 11.8 0.5 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF1776 PF08643.10 ABK74702.1 - 0.14 11.5 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) p450 PF00067.22 ABK74703.1 - 8.7e-25 87.4 0.0 3.6e-18 65.6 0.0 3.0 2 1 0 2 2 2 2 Cytochrome P450 NTP_transf_9 PF04248.12 ABK74704.1 - 9e-27 92.8 0.0 1.7e-23 82.3 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF427) Aminotran_3 PF00202.21 ABK74705.1 - 5.4e-84 282.2 0.0 6.2e-84 282.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 ABK74705.1 - 7.3e-06 25.4 0.0 0.0013 17.9 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II FAD-oxidase_C PF02913.19 ABK74706.1 - 8.3e-53 179.6 0.5 1.2e-52 179.1 0.5 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 ABK74706.1 - 1.2e-44 151.4 3.6 3.8e-40 136.9 0.1 2.6 2 0 0 2 2 2 2 FAD binding domain YjgF_endoribonc PF14588.6 ABK74706.1 - 0.073 13.2 0.4 5.5 7.1 0.1 2.6 2 0 0 2 2 2 0 YjgF/chorismate_mutase-like, putative endoribonuclease Peripla_BP_2 PF01497.18 ABK74707.1 - 8.1e-34 117.2 0.0 1e-33 116.9 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein MoeA_N PF03453.17 ABK74708.1 - 1.7e-39 135.1 6.3 3.1e-39 134.3 6.3 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 ABK74708.1 - 1.3e-18 66.9 0.0 4.9e-18 65.1 0.0 2.1 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) MoCF_biosynth PF00994.24 ABK74708.1 - 3.2e-18 65.8 0.1 7e-18 64.7 0.1 1.6 1 0 0 1 1 1 1 Probable molybdopterin binding domain SnoaL_2 PF12680.7 ABK74709.1 - 1e-06 29.3 1.7 1.4e-06 28.9 1.7 1.3 1 0 0 1 1 1 1 SnoaL-like domain PAPS_reduct PF01507.19 ABK74710.1 - 4.5e-44 150.5 0.0 5.9e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Ish1 PF10281.9 ABK74710.1 - 0.017 15.4 0.0 0.071 13.4 0.0 2.1 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein CoA_transf_3 PF02515.17 ABK74711.1 - 2.1e-125 418.7 0.2 2.5e-125 418.5 0.2 1.0 1 0 0 1 1 1 1 CoA-transferase family III Tyr_Deacylase PF02580.16 ABK74712.1 - 2.5e-51 174.0 0.0 2.7e-51 173.9 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase SPDY PF03771.16 ABK74712.1 - 0.037 13.9 0.3 0.32 11.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF317) BPD_transp_1 PF00528.22 ABK74713.1 - 1.6e-17 63.8 18.7 2e-17 63.5 18.7 1.1 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Thiolase_N PF00108.23 ABK74714.1 - 1.9e-05 24.2 0.5 5.3e-05 22.7 0.5 1.8 1 1 0 1 1 1 1 Thiolase, N-terminal domain Peptidase_M23_N PF18421.1 ABK74714.1 - 0.045 13.6 0.0 0.26 11.2 0.0 2.1 2 0 0 2 2 2 0 Peptidase family M23 N-terminal domain ADH_zinc_N PF00107.26 ABK74715.1 - 2.7e-28 98.5 0.0 4.7e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ABK74715.1 - 1.2e-27 95.9 1.2 2.2e-27 95.1 1.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ABK74715.1 - 4.2e-07 31.1 0.0 7.5e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ABK74715.1 - 7.1e-06 25.7 2.1 3.9e-05 23.3 0.8 2.4 3 0 0 3 3 3 1 Glucose dehydrogenase C-terminus ThiF PF00899.21 ABK74715.1 - 0.00078 18.9 0.5 0.0014 18.1 0.5 1.4 1 0 0 1 1 1 1 ThiF family AlaDh_PNT_C PF01262.21 ABK74715.1 - 0.0065 15.8 3.9 0.012 14.9 3.9 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 ABK74715.1 - 0.018 15.3 0.2 0.035 14.4 0.2 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 ABK74715.1 - 0.034 13.5 0.2 0.06 12.7 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 ABK74715.1 - 0.044 13.7 1.7 0.2 11.5 1.7 1.9 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 ABK74715.1 - 0.056 13.0 2.8 0.15 11.6 2.8 1.8 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 ABK74715.1 - 0.063 13.9 0.5 0.063 13.9 0.5 2.1 2 1 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent PrmA PF06325.13 ABK74715.1 - 0.071 12.5 4.2 0.099 12.0 4.2 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Peptidase_M50 PF02163.22 ABK74716.1 - 1.3e-50 172.0 0.1 1.6e-50 171.7 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M50 PDZ_6 PF17820.1 ABK74716.1 - 4e-08 33.0 0.0 1e-07 31.7 0.0 1.7 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 ABK74716.1 - 4.5e-05 23.7 0.1 0.00012 22.4 0.0 1.7 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 ABK74716.1 - 0.00062 20.1 0.1 0.0017 18.6 0.0 1.7 2 0 0 2 2 2 1 PDZ domain Peptidase_M50B PF13398.6 ABK74716.1 - 0.21 11.2 6.5 0.54 9.8 0.4 2.9 3 0 0 3 3 3 0 Peptidase M50B-like FAD_binding_2 PF00890.24 ABK74717.1 - 0.022 13.8 5.0 0.27 10.3 0.9 2.3 2 1 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 ABK74717.1 - 0.12 11.7 3.2 0.23 10.8 3.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase HpcH_HpaI PF03328.14 ABK74718.1 - 1.4e-29 102.8 0.4 1.7e-29 102.5 0.4 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family NYAP_N PF15439.6 ABK74719.1 - 0.13 11.4 0.1 0.2 10.8 0.1 1.2 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter IMPDH PF00478.25 ABK74721.1 - 4.2e-103 345.0 0.1 6.7e-103 344.3 0.1 1.3 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 ABK74721.1 - 9.6e-11 42.0 0.8 3.8e-05 24.0 0.0 2.7 2 0 0 2 2 2 2 CBS domain His_biosynth PF00977.21 ABK74721.1 - 6e-06 25.9 0.5 0.0025 17.3 0.0 2.3 1 1 1 2 2 2 2 Histidine biosynthesis protein FMN_dh PF01070.18 ABK74721.1 - 6.2e-05 22.2 11.4 0.0001 21.4 10.1 2.1 2 1 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 ABK74721.1 - 0.0011 18.4 11.8 0.0023 17.4 3.9 2.9 2 1 1 3 3 3 2 Nitronate monooxygenase GcpE PF04551.14 ABK74721.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 GcpE protein Glu_synthase PF01645.17 ABK74721.1 - 0.15 11.1 4.4 0.089 11.9 1.9 1.7 1 1 1 2 2 2 0 Conserved region in glutamate synthase Vps16_N PF04841.13 ABK74721.1 - 0.17 10.6 0.0 0.25 10.0 0.0 1.1 1 0 0 1 1 1 0 Vps16, N-terminal region NiFeSe_Hases PF00374.19 ABK74722.1 - 1.2e-67 228.9 0.0 5.4e-63 213.6 0.0 2.1 1 1 0 1 1 1 1 Nickel-dependent hydrogenase Methyltransf_11 PF08241.12 ABK74723.1 - 3.4e-20 72.5 0.0 5.7e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABK74723.1 - 4.2e-18 65.8 0.2 1.1e-17 64.5 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABK74723.1 - 6.1e-11 42.4 0.0 7.2e-11 42.2 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABK74723.1 - 6.1e-11 42.3 0.0 9.3e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ABK74723.1 - 5.5e-08 32.4 0.0 1.6e-07 30.9 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ABK74723.1 - 5.6e-08 33.4 0.0 1.1e-07 32.5 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.13 ABK74723.1 - 0.00054 19.5 0.0 0.00078 18.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 ABK74723.1 - 0.0025 17.4 0.0 0.0049 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain ADH_zinc_N PF00107.26 ABK74723.1 - 0.012 15.6 0.5 0.027 14.5 0.5 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase NodS PF05401.11 ABK74723.1 - 0.014 15.1 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) TehB PF03848.14 ABK74723.1 - 0.062 12.7 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_29 PF03141.16 ABK74723.1 - 0.1 11.2 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase FAD_oxidored PF12831.7 ABK74725.1 - 5.5e-07 29.3 0.1 7.8e-07 28.8 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ABK74725.1 - 1.9e-06 27.4 0.1 2.8e-05 23.6 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 ABK74725.1 - 6.4e-05 22.2 0.4 0.0016 17.6 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 ABK74725.1 - 0.00051 19.3 0.0 0.2 10.9 0.0 2.4 2 0 0 2 2 2 2 Thi4 family SE PF08491.10 ABK74725.1 - 0.002 17.2 0.0 0.0034 16.5 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.14 ABK74725.1 - 0.0076 15.5 0.1 1.1 8.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ABK74725.1 - 0.008 15.1 0.2 0.24 10.2 0.1 2.3 2 0 0 2 2 2 1 Tryptophan halogenase GMC_oxred_N PF00732.19 ABK74725.1 - 0.068 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 GMC oxidoreductase eIF_4G1 PF12152.8 ABK74725.1 - 0.15 12.3 0.0 0.68 10.1 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4G1 LysR_substrate PF03466.20 ABK74726.1 - 2.3e-40 138.2 6.8 3.4e-40 137.7 6.8 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 ABK74726.1 - 4e-21 74.7 6.6 7.8e-21 73.8 3.1 2.4 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family Abhydrolase_1 PF00561.20 ABK74727.1 - 1.8e-11 44.2 0.0 1.9e-10 40.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Sod_Fe_C PF02777.18 ABK74728.1 - 6.3e-36 122.6 0.1 9.7e-36 122.0 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 ABK74728.1 - 8e-31 106.4 4.5 1.3e-30 105.7 4.5 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain HlyIII PF03006.20 ABK74729.1 - 1.4e-41 142.7 17.2 1.7e-41 142.4 17.2 1.0 1 0 0 1 1 1 1 Haemolysin-III related DUF872 PF05915.12 ABK74729.1 - 0.0024 18.0 0.3 0.052 13.7 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF872) FAD_binding_5 PF00941.21 ABK74730.1 - 1.7e-51 174.4 0.0 3.6e-51 173.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 ABK74730.1 - 2e-19 69.7 0.3 4.4e-19 68.6 0.3 1.6 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain AlaDh_PNT_N PF05222.15 ABK74730.1 - 0.019 15.3 0.0 4.9 7.4 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, N-terminal domain GATase_6 PF13522.6 ABK74731.1 - 8.9e-15 55.1 0.0 1.2e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 ABK74731.1 - 5e-08 32.2 0.0 2.5e-06 26.6 0.0 2.6 1 1 1 2 2 2 2 Glutamine amidotransferases class-II eIF-1a PF01176.19 ABK74732.1 - 8.3e-29 99.2 0.1 9.3e-29 99.0 0.1 1.0 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 HAD PF12710.7 ABK74733.1 - 1.1e-28 101.0 0.4 1.7e-28 100.4 0.4 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ABK74733.1 - 4.6e-11 43.4 0.3 1e-10 42.3 0.3 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ABK74733.1 - 1.1e-06 28.6 0.0 9.2e-06 25.6 0.0 2.2 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase DUF4350 PF14258.6 ABK74733.1 - 0.032 14.6 0.1 0.49 10.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) Acyl-CoA_dh_2 PF08028.11 ABK74734.1 - 2.4e-15 57.0 13.7 2.4e-15 57.0 13.7 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK74734.1 - 1.2e-07 32.3 0.0 2.7e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ABK74734.1 - 1.3e-05 25.3 0.0 2.6e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 ABK74734.1 - 0.00013 22.2 5.1 0.00013 22.2 5.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Nitroreductase PF00881.24 ABK74735.1 - 1.4e-10 41.5 0.4 0.0022 18.1 0.0 3.3 2 2 1 3 3 3 3 Nitroreductase family TM1586_NiRdase PF14512.6 ABK74735.1 - 3e-05 23.7 0.0 0.0015 18.1 0.0 2.1 2 0 0 2 2 2 2 Putative TM nitroreductase tRNA-synt_1e PF01406.19 ABK74736.1 - 2.4e-123 411.3 0.0 3e-123 411.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 ABK74736.1 - 5e-13 48.6 0.0 8.4e-06 24.8 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 ABK74736.1 - 1.3e-06 26.9 0.0 0.0014 17.0 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 ABK74736.1 - 1.7e-06 27.2 0.0 0.0075 15.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (K) DALR_2 PF09190.11 ABK74736.1 - 2.6e-06 27.8 1.2 6e-06 26.6 0.1 2.3 2 0 0 2 2 2 1 DALR domain Cupin_7 PF12973.7 ABK74737.1 - 2.3e-15 56.3 0.0 2.9e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 ChrR Cupin-like domain DUF4437 PF14499.6 ABK74737.1 - 8.6e-05 21.8 0.0 0.00028 20.1 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4437) Cupin_2 PF07883.11 ABK74737.1 - 0.00064 19.4 1.4 0.0016 18.1 1.4 1.6 1 1 0 1 1 1 1 Cupin domain PE-PPE PF08237.11 ABK74738.1 - 3.4e-47 160.9 0.2 5.9e-47 160.1 0.2 1.3 1 0 0 1 1 1 1 PE-PPE domain DUF2235 PF09994.9 ABK74738.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) PfkB PF00294.24 ABK74739.1 - 5.4e-35 121.2 7.1 6.8e-35 120.8 7.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 ABK74739.1 - 1.1e-07 31.5 2.0 2.4e-07 30.4 1.7 1.7 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase Dehydratase_LU PF02286.15 ABK74740.1 - 2.3e-257 855.0 0.6 2.9e-257 854.7 0.6 1.0 1 0 0 1 1 1 1 Dehydratase large subunit Dehydratase_MU PF02288.15 ABK74740.1 - 8e-28 96.5 0.0 1.8e-27 95.4 0.0 1.7 1 0 0 1 1 1 1 Dehydratase medium subunit CTP_transf_like PF01467.26 ABK74741.1 - 7e-21 74.9 0.0 8.1e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like Citrate_ly_lig PF08218.11 ABK74741.1 - 5e-07 29.6 0.0 1e-06 28.5 0.0 1.3 1 1 0 1 1 1 1 Citrate lyase ligase C-terminal domain Pantoate_ligase PF02569.15 ABK74741.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase adh_short_C2 PF13561.6 ABK74742.1 - 1.3e-64 217.9 1.9 1.6e-64 217.7 1.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK74742.1 - 4.2e-57 192.8 0.5 5.3e-57 192.4 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK74742.1 - 1.5e-15 57.5 1.6 2e-15 57.2 1.6 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK74742.1 - 1.4e-06 28.0 0.7 2.6e-06 27.1 0.7 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 ABK74742.1 - 0.055 12.8 0.1 0.2 11.0 0.0 1.9 2 1 1 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AdoHcyase_NAD PF00670.21 ABK74742.1 - 0.21 11.7 1.3 1.3 9.1 1.3 2.1 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Glyoxalase PF00903.25 ABK74743.1 - 1.2e-05 25.5 0.0 2.6e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ABK74743.1 - 1.3e-05 25.5 0.0 2.2e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ABK74743.1 - 0.00016 22.4 0.0 0.00024 21.9 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 ABK74743.1 - 0.011 15.9 0.0 0.043 13.9 0.0 1.8 1 1 0 1 1 1 0 Glyoxalase-like domain adh_short_C2 PF13561.6 ABK74744.1 - 8.8e-47 159.6 0.3 1.1e-46 159.3 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK74744.1 - 1.9e-45 154.8 0.5 2.2e-45 154.5 0.5 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK74744.1 - 3.9e-08 33.4 0.3 5.2e-08 33.0 0.3 1.2 1 0 0 1 1 1 1 KR domain Pyr_redox PF00070.27 ABK74744.1 - 0.077 13.6 0.3 0.13 12.8 0.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ABK74744.1 - 0.082 12.1 0.2 0.13 11.5 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain THF_DHG_CYH_C PF02882.19 ABK74744.1 - 0.092 12.1 0.0 0.17 11.2 0.0 1.5 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain HTH_42 PF06224.12 ABK74746.1 - 4.1e-72 243.5 20.9 4.9e-72 243.2 20.9 1.1 1 0 0 1 1 1 1 Winged helix DNA-binding domain Ala_racemase_N PF01168.20 ABK74747.1 - 9.8e-23 80.9 0.0 1.2e-22 80.7 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DUF4140 PF13600.6 ABK74747.1 - 0.072 13.5 0.2 0.38 11.2 0.2 2.2 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Acetyltransf_1 PF00583.25 ABK74748.1 - 5.5e-16 58.9 0.1 7.6e-16 58.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ABK74748.1 - 2.1e-08 34.1 0.0 3.9e-08 33.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ABK74748.1 - 1.1e-07 32.2 0.0 1.5e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ABK74748.1 - 2.6e-07 30.5 0.0 4.9e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_13 PF13880.6 ABK74748.1 - 0.0022 17.9 0.0 0.0037 17.2 0.0 1.3 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase PanZ PF12568.8 ABK74748.1 - 0.0033 17.2 0.0 0.013 15.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 ABK74748.1 - 0.0083 16.2 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 ABK74748.1 - 0.011 15.2 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_6 PF13480.7 ABK74748.1 - 0.021 15.0 0.9 0.084 13.0 0.9 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ABK74748.1 - 0.024 14.7 0.0 0.04 14.0 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 ABK74748.1 - 0.063 12.8 0.0 0.079 12.5 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_4 PF13420.7 ABK74748.1 - 0.087 13.0 0.0 0.13 12.4 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF222 PF02720.17 ABK74749.1 - 9.1e-93 311.0 9.4 9.1e-93 311.0 9.4 1.3 2 0 0 2 2 2 1 Domain of unknown function (DUF222) DUF853 PF05872.12 ABK74750.1 - 2e-200 666.6 0.1 2.7e-200 666.2 0.1 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) DUF87 PF01935.17 ABK74750.1 - 2.3e-07 31.1 0.0 5e-07 30.1 0.0 1.4 1 1 0 1 1 1 1 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 ABK74750.1 - 6.1e-06 25.4 0.2 4.2e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 ABK74750.1 - 0.00011 22.5 0.1 0.028 14.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ABK74750.1 - 0.00018 21.9 2.0 0.056 13.8 0.2 3.3 2 1 1 3 3 3 1 AAA ATPase domain ResIII PF04851.15 ABK74750.1 - 0.00079 19.5 0.0 0.067 13.2 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit FtsK_SpoIIIE PF01580.18 ABK74750.1 - 0.0011 18.4 0.1 0.0035 16.7 0.1 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_30 PF13604.6 ABK74750.1 - 0.0026 17.5 0.4 0.0094 15.7 0.3 2.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 ABK74750.1 - 0.0075 16.7 0.1 2.2 8.7 0.1 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 ABK74750.1 - 0.021 14.9 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_10 PF12846.7 ABK74750.1 - 0.024 13.6 0.0 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain Zot PF05707.12 ABK74750.1 - 0.03 14.0 0.0 0.071 12.7 0.0 1.6 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) Isochorismatase PF00857.20 ABK74750.1 - 0.042 14.0 0.0 0.23 11.6 0.0 2.1 3 0 0 3 3 3 0 Isochorismatase family T2SSE PF00437.20 ABK74750.1 - 0.053 12.6 0.0 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein DEAD PF00270.29 ABK74750.1 - 0.16 11.8 0.1 4.5 7.0 0.1 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_6 PF12774.7 ABK74750.1 - 0.21 10.5 0.1 0.36 9.7 0.1 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region DUF2075 PF09848.9 ABK74750.1 - 0.24 10.6 0.2 3.8 6.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) EthD PF07110.11 ABK74751.1 - 6.8e-08 33.6 1.7 1.7e-07 32.2 1.2 1.9 2 0 0 2 2 2 1 EthD domain MmlI PF09448.10 ABK74751.1 - 0.0064 16.9 0.0 0.012 16.1 0.0 1.5 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase Catalase PF00199.19 ABK74752.1 - 1.2e-17 64.1 0.0 4e-17 62.4 0.0 1.6 1 1 0 1 1 1 1 Catalase Hydrolase_4 PF12146.8 ABK74753.1 - 0.019 14.3 0.1 0.82 8.9 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF2000 PF09391.10 ABK74754.1 - 0.011 15.6 1.1 0.11 12.5 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2000) Thioredoxin PF00085.20 ABK74755.1 - 6.8e-27 93.5 0.1 8e-27 93.2 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 ABK74755.1 - 4.2e-08 33.4 0.0 1.8e-05 25.0 0.0 2.6 1 1 2 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 ABK74755.1 - 4.3e-07 30.4 0.1 2.7e-06 27.8 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 ABK74755.1 - 0.00042 20.1 0.1 0.00054 19.7 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 ABK74755.1 - 0.00059 19.7 0.0 0.00072 19.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 ABK74755.1 - 0.00075 19.6 0.7 0.0011 19.1 0.1 1.7 2 1 0 2 2 2 1 Thioredoxin-like Redoxin PF08534.10 ABK74755.1 - 0.011 15.5 0.2 0.041 13.6 0.2 1.7 1 1 1 2 2 2 0 Redoxin Peptidase_M24 PF00557.24 ABK74755.1 - 0.033 13.9 0.1 0.52 10.0 0.0 2.0 2 0 0 2 2 2 0 Metallopeptidase family M24 OST3_OST6 PF04756.13 ABK74755.1 - 0.034 13.5 0.1 0.036 13.4 0.1 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 ABK74755.1 - 0.062 13.5 0.1 0.29 11.4 0.0 1.9 2 0 0 2 2 2 0 Glutaredoxin tRNA-synt_1e PF01406.19 ABK74756.1 - 7.3e-84 281.7 0.0 9.4e-84 281.3 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 ABK74756.1 - 2.1e-08 33.3 0.0 0.0024 16.7 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 ABK74756.1 - 0.00048 18.5 0.0 0.0016 16.8 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 ABK74756.1 - 0.19 10.6 0.0 4.8 6.0 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (K) FAD_binding_7 PF03441.14 ABK74757.1 - 1.1e-73 247.0 1.5 1.7e-73 246.4 1.5 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 ABK74757.1 - 3.9e-39 134.3 0.0 7.6e-39 133.4 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase DUF179 PF02622.15 ABK74759.1 - 7.5e-36 123.5 0.0 9.8e-36 123.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 AMP-binding PF00501.28 ABK74760.1 - 1.5e-54 185.3 1.2 3e-48 164.5 0.0 2.5 2 1 1 3 3 3 2 AMP-binding enzyme PP-binding PF00550.25 ABK74760.1 - 7.9e-10 39.0 0.1 2.4e-09 37.4 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF2070 PF09843.9 ABK74760.1 - 3.7 5.7 8.3 5.1 5.3 8.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Phage_holin_2_1 PF04971.12 ABK74760.1 - 7.5 6.6 6.5 21 5.2 0.4 2.7 2 0 0 2 2 2 0 Bacteriophage P21 holin S Amidohydro_3 PF07969.11 ABK74761.1 - 6.3e-20 72.1 2.6 6.2e-11 42.4 0.4 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 ABK74761.1 - 4.2e-10 39.5 0.1 0.00012 21.5 0.0 2.6 3 0 0 3 3 3 2 Amidohydrolase family RHINO PF15319.6 ABK74761.1 - 0.12 12.3 0.4 0.2 11.7 0.4 1.3 1 0 0 1 1 1 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein BPD_transp_1 PF00528.22 ABK74762.1 - 1.1e-21 77.4 13.7 1.8e-21 76.7 13.7 1.3 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component DUF543 PF04418.12 ABK74762.1 - 4.9 7.2 4.9 4.2 7.4 0.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF543) CBM_48 PF02922.18 ABK74764.1 - 3.7e-19 68.9 0.0 7.2e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 ABK74764.1 - 1.2e-16 61.3 0.0 4.4e-07 29.8 0.0 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Cellulase PF00150.18 ABK74764.1 - 0.1 12.0 0.0 0.29 10.5 0.0 1.7 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) NAD_binding_1 PF00175.21 ABK74765.1 - 2.2e-11 44.4 0.0 4.5e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Fer2 PF00111.27 ABK74765.1 - 7.6e-10 38.6 0.6 1.3e-09 37.9 0.6 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FAD_binding_6 PF00970.24 ABK74765.1 - 1.7e-08 34.7 0.0 3.4e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 ABK74765.1 - 0.0022 18.1 0.0 0.043 13.9 0.0 2.1 1 1 1 2 2 2 1 Ferric reductase NAD binding domain COX1 PF00115.20 ABK74766.1 - 2.7e-147 491.1 65.6 3.2e-147 490.9 65.6 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I PEN-2 PF10251.9 ABK74766.1 - 0.94 9.9 5.9 2.8 8.4 0.1 3.7 3 0 0 3 3 3 0 Presenilin enhancer-2 subunit of gamma secretase Nitroreductase PF00881.24 ABK74767.1 - 7.7e-28 97.7 0.0 9.4e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 ABK74767.1 - 0.0013 18.3 0.0 1.5 8.3 0.0 2.1 2 0 0 2 2 2 2 Putative TM nitroreductase PGM_PMM_II PF02879.16 ABK74767.1 - 0.23 12.1 0.6 0.47 11.1 0.6 1.5 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II SNO PF01174.19 ABK74770.1 - 2.5e-57 193.8 0.0 2.8e-57 193.6 0.0 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 ABK74770.1 - 2.1e-09 37.2 0.0 3e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 ABK74770.1 - 1.7e-06 27.9 0.0 2.2e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family S51 GATase PF00117.28 ABK74770.1 - 1.2e-05 25.2 0.0 1.6e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 ABK74770.1 - 0.047 13.5 0.0 0.096 12.5 0.0 1.5 2 0 0 2 2 2 0 DJ-1/PfpI family Peptidase_C26 PF07722.13 ABK74770.1 - 0.1 12.4 2.6 5.1 6.8 0.3 2.8 2 1 0 2 2 2 0 Peptidase C26 ClpS PF02617.17 ABK74771.1 - 4.4e-21 74.4 0.0 5.4e-21 74.2 0.0 1.1 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS MOSC PF03473.17 ABK74772.1 - 3.8e-12 46.4 0.0 1.3e-11 44.6 0.0 1.8 2 0 0 2 2 2 1 MOSC domain MOSC_N PF03476.16 ABK74772.1 - 1.8e-08 34.3 0.0 3.1e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain HAD_2 PF13419.6 ABK74773.1 - 4.3e-27 95.3 0.0 5e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ABK74773.1 - 3.3e-20 73.3 0.1 3.1e-19 70.1 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ABK74773.1 - 1.6e-07 32.0 0.0 2.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ABK74773.1 - 2.3e-05 24.3 0.0 5.2e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 ABK74773.1 - 3.4e-05 23.9 0.0 0.0076 16.3 0.0 3.1 1 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase IMS PF00817.20 ABK74774.1 - 2.4e-49 167.2 0.0 1e-48 165.1 0.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 ABK74774.1 - 1.1e-16 61.6 0.2 5.1e-16 59.4 0.1 1.9 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 ABK74774.1 - 1.3e-09 37.9 0.1 3.5e-09 36.4 0.0 1.8 2 0 0 2 2 2 1 IMS family HHH motif HHH_5 PF14520.6 ABK74774.1 - 9.4e-06 26.1 0.1 2.9e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 ABK74774.1 - 1.6e-05 24.7 0.2 4.7e-05 23.1 0.1 1.8 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda UTRA PF07702.13 ABK74775.1 - 6.8e-32 110.3 0.1 1.2e-31 109.4 0.0 1.4 2 0 0 2 2 2 1 UTRA domain GntR PF00392.21 ABK74775.1 - 6.9e-18 64.1 3.0 1.2e-15 56.9 0.2 2.8 3 0 0 3 3 3 2 Bacterial regulatory proteins, gntR family HTH_11 PF08279.12 ABK74775.1 - 0.0002 21.2 0.1 0.0021 17.9 0.0 2.2 1 1 1 2 2 2 1 HTH domain HTH_DeoR PF08220.12 ABK74775.1 - 0.0012 18.5 0.0 0.0038 17.0 0.0 1.8 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain MarR_2 PF12802.7 ABK74775.1 - 0.0026 17.6 0.2 0.013 15.4 0.1 2.2 1 1 1 2 2 2 1 MarR family Rrf2 PF02082.20 ABK74775.1 - 0.0033 17.7 0.0 0.0087 16.4 0.0 1.8 1 0 0 1 1 1 1 Transcriptional regulator HTH_20 PF12840.7 ABK74775.1 - 0.035 14.2 0.0 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 ABK74775.1 - 0.045 13.7 0.1 0.16 12.0 0.0 1.9 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_5 PF01022.20 ABK74775.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family TrmB PF01978.19 ABK74775.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_41 PF14502.6 ABK74775.1 - 0.097 12.4 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_28 PF13518.6 ABK74775.1 - 0.13 12.4 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain adh_short_C2 PF13561.6 ABK74776.1 - 1.9e-26 93.1 0.3 7.1e-19 68.3 0.0 2.5 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK74776.1 - 1.6e-16 60.4 0.1 5.2e-09 35.8 0.2 2.6 2 1 0 2 2 2 2 short chain dehydrogenase Epimerase PF01370.21 ABK74776.1 - 3.1e-07 30.1 0.0 4.3e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family UvrB_inter PF17757.1 ABK74777.1 - 1.3e-33 115.0 0.0 2.5e-32 110.9 0.0 2.8 3 0 0 3 3 3 1 UvrB interaction domain UvrB PF12344.8 ABK74777.1 - 4.3e-22 77.7 1.7 4.3e-22 77.7 1.7 2.0 2 0 0 2 2 2 1 Ultra-violet resistance protein B Helicase_C PF00271.31 ABK74777.1 - 9.3e-18 64.6 0.1 1.9e-17 63.6 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ABK74777.1 - 3.5e-09 36.9 0.0 2.9e-08 33.9 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UVR PF02151.19 ABK74777.1 - 4.9e-08 32.5 6.0 4.9e-08 32.5 6.0 2.6 2 0 0 2 2 1 1 UvrB/uvrC motif DEAD PF00270.29 ABK74777.1 - 3.5e-05 23.6 0.0 0.00036 20.3 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_19 PF13245.6 ABK74777.1 - 0.00015 22.1 0.0 0.082 13.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ABK74777.1 - 0.0009 19.0 0.0 0.065 12.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ABK74777.1 - 0.00098 19.1 0.0 0.0089 16.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ABK74777.1 - 0.0016 18.7 0.0 0.091 13.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 ABK74777.1 - 0.0041 17.0 0.0 0.014 15.2 0.0 1.9 2 0 0 2 2 2 1 Helicase FtsK_SpoIIIE PF01580.18 ABK74777.1 - 0.0042 16.5 1.6 8.3 5.7 0.0 3.3 3 0 0 3 3 3 1 FtsK/SpoIIIE family DUF87 PF01935.17 ABK74777.1 - 0.012 15.8 0.0 0.041 14.0 0.0 1.9 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_16 PF13191.6 ABK74777.1 - 0.012 16.0 0.1 0.13 12.6 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain CdvA PF18822.1 ABK74777.1 - 0.049 13.5 5.9 1.6 8.6 0.2 3.1 3 0 0 3 3 3 0 CdvA-like coiled-coil domain UB2H PF14814.6 ABK74777.1 - 0.11 12.5 0.0 0.44 10.6 0.0 2.0 2 0 0 2 2 1 0 Bifunctional transglycosylase second domain AAA_7 PF12775.7 ABK74777.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AIG1 PF04548.16 ABK74777.1 - 0.13 11.6 0.0 0.29 10.4 0.0 1.6 1 0 0 1 1 1 0 AIG1 family DNA_pol_A PF00476.20 ABK74777.1 - 0.19 10.7 0.3 0.46 9.5 0.0 1.7 2 0 0 2 2 2 0 DNA polymerase family A ApoLp-III PF07464.11 ABK74777.1 - 0.19 11.8 0.1 27 4.8 0.1 2.6 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF3592 PF12158.8 ABK74778.1 - 9.6e-05 22.5 0.2 0.00027 21.0 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3592) Pyr_redox_2 PF07992.14 ABK74779.1 - 1.1e-65 221.8 5.7 1.4e-65 221.5 5.7 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ABK74779.1 - 1e-35 122.3 0.0 3.7e-35 120.5 0.0 2.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 ABK74779.1 - 4.6e-22 78.4 2.6 5.9e-20 71.6 0.6 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ABK74779.1 - 1.2e-09 37.9 9.4 1.6e-07 30.9 2.3 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ABK74779.1 - 8.3e-09 35.3 1.4 1.6e-07 31.1 0.4 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ABK74779.1 - 1.9e-07 30.7 3.1 0.0069 15.7 0.1 3.2 2 1 1 3 3 3 2 FAD binding domain FAD_binding_2 PF00890.24 ABK74779.1 - 3.3e-07 29.8 8.5 1.9e-05 23.9 0.8 3.4 2 1 1 3 3 3 1 FAD binding domain GIDA PF01134.22 ABK74779.1 - 1.1e-06 28.1 7.8 2.5e-06 26.8 0.7 2.9 3 1 0 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.14 ABK74779.1 - 2.1e-06 26.7 8.9 0.0054 15.5 0.2 3.4 2 1 1 3 3 3 3 HI0933-like protein NAD_binding_8 PF13450.6 ABK74779.1 - 9.9e-06 25.7 2.3 0.021 15.1 0.1 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ABK74779.1 - 4.6e-05 22.8 2.6 0.03 13.6 0.1 2.9 3 0 0 3 3 3 2 Thi4 family 3HCDH_N PF02737.18 ABK74779.1 - 5.8e-05 23.0 1.2 0.0007 19.5 0.1 2.8 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain LpxI_N PF17930.1 ABK74779.1 - 0.00017 21.4 0.1 0.31 10.9 0.0 2.7 2 0 0 2 2 2 2 LpxI N-terminal domain DAO PF01266.24 ABK74779.1 - 0.00018 21.2 10.2 0.062 12.9 0.1 3.6 3 1 0 3 3 3 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 ABK74779.1 - 0.0033 16.8 0.3 0.016 14.5 0.3 1.8 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 ABK74779.1 - 0.015 14.4 3.1 1.3 8.0 0.1 3.1 2 1 1 3 3 3 0 Lycopene cyclase protein K_oxygenase PF13434.6 ABK74779.1 - 0.026 13.7 0.1 2 7.5 0.0 2.3 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 ABK74779.1 - 0.028 13.7 6.0 1.2 8.3 0.1 2.7 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ABK74779.1 - 0.028 13.8 0.1 0.19 11.1 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 ABK74779.1 - 0.034 13.8 0.0 0.066 12.8 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA XdhC_C PF13478.6 ABK74779.1 - 0.079 13.5 0.1 1.8 9.1 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain TrkA_N PF02254.18 ABK74779.1 - 0.26 11.6 0.0 0.26 11.6 0.0 2.5 3 0 0 3 3 2 0 TrkA-N domain FCD PF07729.12 ABK74780.1 - 9.9e-23 80.9 6.6 1.9e-22 80.0 6.6 1.5 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 ABK74780.1 - 1e-17 63.5 0.5 2.6e-17 62.2 0.1 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family TrmB PF01978.19 ABK74780.1 - 4.3e-05 23.3 0.0 8.5e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_27 PF13463.6 ABK74780.1 - 0.00071 20.0 0.0 0.0033 17.9 0.0 2.1 2 0 0 2 2 2 1 Winged helix DNA-binding domain MarR_2 PF12802.7 ABK74780.1 - 0.0024 17.7 0.1 0.022 14.6 0.0 2.4 2 0 0 2 2 2 1 MarR family Rrf2 PF02082.20 ABK74780.1 - 0.0045 17.3 0.0 0.039 14.3 0.0 2.5 3 1 0 3 3 3 1 Transcriptional regulator TFIIE_alpha PF02002.17 ABK74780.1 - 0.045 13.6 0.0 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 TFIIE alpha subunit HTH_24 PF13412.6 ABK74780.1 - 0.053 13.1 0.0 0.17 11.5 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding PaaX PF07848.12 ABK74780.1 - 0.11 12.7 0.0 0.5 10.6 0.0 2.0 2 0 0 2 2 2 0 PaaX-like protein Fe_dep_repress PF01325.19 ABK74780.1 - 0.12 12.6 0.0 0.68 10.2 0.0 2.2 3 0 0 3 3 3 0 Iron dependent repressor, N-terminal DNA binding domain HTH_28 PF13518.6 ABK74780.1 - 0.39 10.9 3.1 1.6 8.9 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain TetR_C_21 PF17926.1 ABK74781.1 - 2.6e-16 59.8 0.1 4e-16 59.1 0.1 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK74781.1 - 9.3e-14 51.0 0.0 1.5e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_29 PF17938.1 ABK74781.1 - 0.0021 18.1 0.0 0.0041 17.2 0.0 1.5 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Amidohydro_2 PF04909.14 ABK74782.1 - 9.7e-25 87.9 1.2 1.1e-24 87.7 1.2 1.2 1 0 0 1 1 1 1 Amidohydrolase TetR_N PF00440.23 ABK74783.1 - 2.9e-13 49.4 0.3 6e-13 48.4 0.3 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family OTCace_N PF02729.21 ABK74784.1 - 5.9e-41 139.9 0.0 8.5e-41 139.4 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 ABK74784.1 - 1.5e-21 77.1 0.0 4e-21 75.7 0.0 1.7 1 1 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF4431 PF14485.6 ABK74784.1 - 0.059 13.2 0.0 0.46 10.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4431) PA PF02225.22 ABK74784.1 - 0.14 12.2 0.0 2.4 8.3 0.0 2.2 1 1 1 2 2 2 0 PA domain Glyoxalase PF00903.25 ABK74785.1 - 5.4e-08 33.1 0.1 6.8e-08 32.8 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ABK74785.1 - 2.2e-05 25.2 0.0 2.8e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 ABK74785.1 - 0.054 13.8 0.0 0.41 10.9 0.0 2.0 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Adenine_deam_C PF13382.6 ABK74785.1 - 0.12 11.7 0.6 0.28 10.5 0.2 1.7 2 0 0 2 2 2 0 Adenine deaminase C-terminal domain Pfk_N PF18468.1 ABK74785.1 - 0.14 12.6 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphofructokinase N-terminal domain yeast DDE_Tnp_1 PF01609.21 ABK74786.1 - 1.9e-13 50.5 0.0 6.9e-13 48.7 0.0 1.8 1 1 0 1 1 1 1 Transposase DDE domain DUF742 PF05331.11 ABK74788.1 - 1.6e-31 108.4 0.1 1.9e-31 108.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF742) HTH_IclR PF09339.10 ABK74788.1 - 0.00051 19.8 0.0 0.00079 19.2 0.0 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 ABK74788.1 - 0.0075 16.1 0.1 0.013 15.4 0.1 1.4 1 0 0 1 1 1 1 MarR family EutK_C PF16365.5 ABK74788.1 - 0.0094 16.0 0.0 0.056 13.5 0.0 2.0 2 0 0 2 2 2 1 Ethanolamine utilization protein EutK C-terminus HTH_24 PF13412.6 ABK74788.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_Tnp_ISL3 PF13542.6 ABK74788.1 - 0.076 12.4 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Oxidored_q3 PF00499.20 ABK74789.1 - 5.8e-31 107.2 21.7 8.8e-31 106.6 21.7 1.3 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF1290 PF06947.12 ABK74790.1 - 3.6e-34 116.7 4.3 5.6e-34 116.1 4.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1290) 7TMR-DISM_7TM PF07695.11 ABK74790.1 - 0.033 14.1 5.0 0.037 13.9 5.0 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling DUF1129 PF06570.11 ABK74790.1 - 0.81 9.1 3.0 0.49 9.8 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) DUF3043 PF11241.8 ABK74790.1 - 6.4 6.8 4.9 1.7 8.6 1.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3043) CPP1-like PF11833.8 ABK74790.1 - 6.9 6.3 6.1 8.9 5.9 0.7 2.0 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like GTP_EFTU PF00009.27 ABK74792.1 - 4.8e-48 163.3 0.0 7.1e-48 162.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RF3_C PF16658.5 ABK74792.1 - 2.3e-38 131.0 0.0 3.4e-38 130.4 0.0 1.3 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 ABK74792.1 - 7.2e-08 32.5 0.0 1.4e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 ABK74792.1 - 0.0035 17.7 0.0 0.0068 16.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 ABK74792.1 - 0.015 15.2 0.0 4.7 7.1 0.0 2.5 1 1 0 2 2 2 0 RsgA GTPase MeaB PF03308.16 ABK74792.1 - 0.09 11.7 0.1 0.3 10.0 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NUDIX PF00293.28 ABK74793.1 - 2.7e-16 59.8 0.2 5.1e-16 58.9 0.2 1.5 1 0 0 1 1 1 1 NUDIX domain His_Phos_1 PF00300.22 ABK74793.1 - 2.4e-11 43.7 0.7 1.8e-10 40.9 1.2 2.0 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 1) GntP_permease PF02447.16 ABK74794.1 - 2.3e-126 422.1 46.4 2.7e-126 421.9 46.4 1.0 1 0 0 1 1 1 1 GntP family permease CitMHS PF03600.16 ABK74794.1 - 3.4e-23 82.3 41.1 5.7e-23 81.5 41.1 1.4 1 0 0 1 1 1 1 Citrate transporter MerR_1 PF13411.6 ABK74795.1 - 4.1e-13 49.2 0.0 6.3e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 ABK74795.1 - 0.012 15.4 0.0 0.041 13.7 0.0 2.0 1 0 0 1 1 1 0 MerR family regulatory protein Cupin_2 PF07883.11 ABK74796.1 - 6e-10 38.7 0.2 8.4e-10 38.2 0.2 1.2 1 0 0 1 1 1 1 Cupin domain Defensin_propep PF00879.18 ABK74796.1 - 0.013 15.7 0.3 0.028 14.7 0.3 1.6 1 0 0 1 1 1 0 Defensin propeptide Intg_mem_TP0381 PF09529.10 ABK74797.1 - 8e-56 189.1 12.3 9.8e-56 188.8 12.3 1.0 1 0 0 1 1 1 1 Integral membrane protein (intg_mem_TP0381) DUF4118 PF13493.6 ABK74797.1 - 0.0051 16.6 0.1 0.0051 16.6 0.1 4.0 2 2 1 3 3 3 2 Domain of unknown function (DUF4118) Polysacc_synt_C PF14667.6 ABK74797.1 - 0.014 15.4 2.9 0.014 15.4 2.9 2.5 2 1 1 3 3 3 0 Polysaccharide biosynthesis C-terminal domain Peptidase_U4 PF03419.13 ABK74797.1 - 0.5 9.6 8.5 0.84 8.9 0.5 2.1 1 1 1 2 2 2 0 Sporulation factor SpoIIGA ECF_trnsprt PF12822.7 ABK74797.1 - 2.2 8.4 9.8 0.34 11.0 0.7 2.2 1 1 1 2 2 2 0 ECF transporter, substrate-specific component DUF4293 PF14126.6 ABK74797.1 - 4.3 7.6 7.4 4.4 7.5 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4293) Glycos_transf_2 PF00535.26 ABK74799.1 - 2.5e-17 63.2 1.1 1.3e-16 60.8 0.1 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ABK74799.1 - 3.8e-06 27.0 0.0 1.7e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 ABK74799.1 - 1.7e-05 25.2 1.4 0.00025 21.5 0.2 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 ABK74799.1 - 0.016 14.7 0.0 2.1 7.7 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase like family 2 SIS PF01380.22 ABK74800.1 - 2.4e-22 79.2 0.0 5.6e-13 48.9 0.0 2.2 2 0 0 2 2 2 2 SIS domain IF2_N PF04760.15 ABK74800.1 - 0.054 13.3 0.0 0.99 9.3 0.0 2.5 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region BPD_transp_1 PF00528.22 ABK74801.1 - 1.1e-14 54.6 18.9 1.1e-14 54.6 18.9 2.2 1 1 1 2 2 2 2 Binding-protein-dependent transport system inner membrane component Meth_synt_2 PF01717.18 ABK74802.1 - 3.5e-62 210.6 0.0 4e-62 210.4 0.0 1.0 1 0 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Glyco_hydro_38N PF01074.22 ABK74803.1 - 1.1e-71 241.6 0.3 1.5e-71 241.1 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain NPCBM_assoc PF10633.9 ABK74803.1 - 2.6e-21 75.7 6.0 5.9e-19 68.1 0.3 2.9 2 0 0 2 2 2 2 NPCBM-associated, NEW3 domain of alpha-galactosidase Alpha-mann_mid PF09261.11 ABK74803.1 - 5.4e-12 45.7 0.0 9.7e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro_38C PF07748.13 ABK74803.1 - 0.00026 21.2 0.0 0.0094 16.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain DDE_Tnp_1 PF01609.21 ABK74804.1 - 2.6e-15 56.7 0.0 6.8e-15 55.3 0.0 1.7 1 1 0 1 1 1 1 Transposase DDE domain adh_short_C2 PF13561.6 ABK74805.1 - 9.5e-68 228.2 0.0 1.1e-67 228.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK74805.1 - 2.7e-49 167.3 0.0 3.3e-49 167.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK74805.1 - 1.2e-05 25.3 0.6 3.7e-05 23.7 0.6 1.8 1 1 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 ABK74805.1 - 0.00064 19.8 0.1 0.001 19.2 0.1 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Epimerase PF01370.21 ABK74805.1 - 0.0035 16.8 0.0 0.005 16.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_trans_4_4 PF13579.6 ABK74805.1 - 0.034 14.6 0.6 0.27 11.7 0.2 2.1 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain APH PF01636.23 ABK74806.1 - 1.1e-33 117.2 5.6 1.3e-33 116.9 5.6 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 ABK74806.1 - 0.1 11.8 0.0 2.9 7.0 0.0 2.3 1 1 1 2 2 2 0 Fructosamine kinase dCMP_cyt_deam_2 PF08211.12 ABK74807.1 - 1.4e-10 41.5 0.8 4e-07 30.3 0.1 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_1 PF00383.23 ABK74807.1 - 2.9e-10 39.9 0.0 3.5e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region FtsX PF02687.21 ABK74808.1 - 0.35 11.4 5.6 0.49 10.9 5.6 1.2 1 0 0 1 1 1 0 FtsX-like permease family LapA_dom PF06305.11 ABK74808.1 - 0.58 10.0 5.8 1.3 8.9 0.5 2.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF4282 PF14110.6 ABK74808.1 - 1.6 9.5 6.3 2.5 8.9 6.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4282) Trp_oprn_chp PF09534.10 ABK74808.1 - 1.7 8.4 11.3 2.2 8.1 11.3 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Bac_luciferase PF00296.20 ABK74809.1 - 2.6e-51 174.9 1.8 3.5e-51 174.5 1.8 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase CN_hydrolase PF00795.22 ABK74810.1 - 3e-23 82.5 0.2 3.5e-23 82.3 0.2 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CbiM PF01891.16 ABK74811.1 - 4.3e-59 199.8 24.3 4.9e-59 199.6 24.3 1.0 1 0 0 1 1 1 1 Cobalt uptake substrate-specific transmembrane region RRF PF01765.19 ABK74812.1 - 4.1e-61 205.7 1.0 5.3e-61 205.3 1.0 1.1 1 0 0 1 1 1 1 Ribosome recycling factor Ferritin-like PF12902.7 ABK74812.1 - 0.097 12.5 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Ferritin-like DUF883 PF05957.13 ABK74812.1 - 0.11 13.1 6.1 0.097 13.3 3.4 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Phage_TAC_4 PF08748.11 ABK74812.1 - 0.22 11.9 2.6 0.37 11.1 2.6 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone Sigma70_r4_2 PF08281.12 ABK74813.1 - 3.2e-06 26.7 0.5 8.9e-06 25.3 0.0 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 ABK74813.1 - 0.00035 20.3 0.8 0.001 18.8 0.8 1.9 1 1 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 ABK74813.1 - 0.0012 18.3 0.1 0.0032 17.0 0.1 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 DUF134 PF02001.16 ABK74813.1 - 0.047 14.2 0.2 0.51 10.9 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF134 ESPR PF13018.6 ABK74813.1 - 0.17 11.7 0.4 0.89 9.4 0.1 2.2 2 0 0 2 2 2 0 Extended Signal Peptide of Type V secretion system Aerolysin PF01117.20 ABK74813.1 - 0.2 10.8 0.0 0.24 10.6 0.0 1.1 1 0 0 1 1 1 0 Aerolysin toxin IclR PF01614.18 ABK74815.1 - 2.7e-21 75.7 0.0 4.5e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 ABK74815.1 - 6.7e-15 54.6 1.2 6.7e-15 54.6 1.2 2.1 2 0 0 2 2 2 1 IclR helix-turn-helix domain MarR_2 PF12802.7 ABK74815.1 - 1.4e-06 28.0 0.4 3.1e-06 27.0 0.4 1.6 1 0 0 1 1 1 1 MarR family HTH_11 PF08279.12 ABK74815.1 - 3.3e-06 26.9 0.1 5.1e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 HTH domain HTH_24 PF13412.6 ABK74815.1 - 7.5e-06 25.4 0.1 1.4e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 ABK74815.1 - 0.00034 20.4 0.1 0.00065 19.5 0.1 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Sigma70_r4 PF04545.16 ABK74815.1 - 0.0015 18.0 0.0 0.0041 16.6 0.0 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_20 PF12840.7 ABK74815.1 - 0.0033 17.4 1.3 0.0095 16.0 0.3 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 ABK74815.1 - 0.0039 17.1 0.1 0.0087 16.0 0.1 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Rrf2 PF02082.20 ABK74815.1 - 0.0049 17.2 0.0 0.013 15.9 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulator HTH_5 PF01022.20 ABK74815.1 - 0.0069 16.2 0.0 0.019 14.8 0.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_AsnC-type PF13404.6 ABK74815.1 - 0.016 15.0 0.2 0.043 13.7 0.2 1.8 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain MarR PF01047.22 ABK74815.1 - 0.022 14.7 0.1 0.044 13.7 0.1 1.5 1 0 0 1 1 1 0 MarR family Dimerisation PF08100.11 ABK74815.1 - 0.047 13.7 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain HU-CCDC81_euk_2 PF18289.1 ABK74815.1 - 0.061 13.5 0.0 1.5 9.0 0.0 2.6 3 0 0 3 3 3 0 CCDC81 eukaryotic HU domain 2 HTH_26 PF13443.6 ABK74815.1 - 0.067 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_3 PF01381.22 ABK74815.1 - 0.067 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix HTH_23 PF13384.6 ABK74815.1 - 0.079 12.8 0.0 0.25 11.2 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain Sigma54_DBD PF04552.13 ABK74815.1 - 0.092 12.4 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Sigma-54, DNA binding domain AsnC_trans_reg PF01037.21 ABK74816.1 - 3.3e-10 39.8 0.2 3.9e-10 39.6 0.2 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain VWA_CoxE PF05762.14 ABK74817.1 - 1.7e-31 109.4 8.1 2.2e-31 109.0 7.6 1.5 1 1 0 1 1 1 1 VWA domain containing CoxE-like protein DUF3151 PF11349.8 ABK74818.1 - 7.9e-61 203.8 0.5 8.8e-61 203.6 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3151) PfkB PF00294.24 ABK74819.1 - 2.1e-35 122.5 2.7 2.4e-35 122.3 2.7 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Response_reg PF00072.24 ABK74820.1 - 8.7e-29 100.0 0.0 3.8e-28 97.9 0.0 1.9 2 0 0 2 2 2 1 Response regulator receiver domain Trans_reg_C PF00486.28 ABK74820.1 - 1.1e-22 79.9 0.0 2.2e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Lipase_GDSL_2 PF13472.6 ABK74820.1 - 0.0041 17.5 0.0 0.0058 17.0 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family FtsX_ECD PF18075.1 ABK74821.1 - 1.3e-13 51.4 0.0 2e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 FtsX extracellular domain FtsX PF02687.21 ABK74821.1 - 1.1e-06 29.1 3.9 1.1e-06 29.1 3.9 2.7 3 0 0 3 3 3 1 FtsX-like permease family LapA_dom PF06305.11 ABK74821.1 - 6.6 6.6 8.3 4.7 7.1 0.8 3.0 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Sugar_tr PF00083.24 ABK74822.1 - 1.7e-31 109.6 32.3 5.3e-19 68.4 9.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ABK74822.1 - 6.8e-24 84.4 52.6 4.7e-14 52.1 22.0 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ABK74822.1 - 2.7e-07 29.5 32.0 9.7e-07 27.7 30.5 2.1 1 1 1 2 2 2 1 MFS/sugar transport protein HTH_46 PF15977.5 ABK74822.1 - 0.08 13.0 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA binding Redoxin PF08534.10 ABK74823.1 - 5.8e-25 87.7 0.0 6.7e-25 87.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 ABK74823.1 - 4.3e-15 55.7 0.0 5.2e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family STAS_2 PF13466.6 ABK74824.1 - 1.8e-07 31.4 1.0 2.8e-07 30.8 1.0 1.3 1 0 0 1 1 1 1 STAS domain STAS PF01740.21 ABK74824.1 - 8e-05 22.3 0.0 9.2e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 STAS domain TrkA_N PF02254.18 ABK74825.1 - 4.2e-24 85.0 0.3 6.2e-24 84.5 0.3 1.3 1 0 0 1 1 1 1 TrkA-N domain TrkA_C PF02080.21 ABK74825.1 - 2e-11 43.6 1.7 2.4e-10 40.1 0.2 2.5 2 1 0 2 2 2 1 TrkA-C domain NAD_binding_10 PF13460.6 ABK74825.1 - 1.6e-06 28.1 0.3 3e-06 27.3 0.3 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_7 PF13241.6 ABK74825.1 - 2.8e-06 27.7 0.3 5.4e-06 26.8 0.3 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding ApbA PF02558.16 ABK74825.1 - 3.1e-05 23.7 0.0 5.6e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 ABK74825.1 - 3.5e-05 23.9 0.1 7.8e-05 22.8 0.1 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 ABK74825.1 - 0.00019 21.9 0.3 0.00039 21.0 0.3 1.5 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.24 ABK74825.1 - 0.00066 19.4 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 ABK74825.1 - 0.001 19.0 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DapB_N PF01113.20 ABK74825.1 - 0.003 17.7 0.1 0.0053 16.9 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_Gly3P_dh_N PF01210.23 ABK74825.1 - 0.0046 16.9 0.0 0.0076 16.2 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Epimerase PF01370.21 ABK74825.1 - 0.0068 15.9 0.1 0.009 15.5 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 ABK74825.1 - 0.0093 16.2 0.1 0.022 15.0 0.1 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Gp_dh_N PF00044.24 ABK74825.1 - 0.013 15.8 0.1 0.035 14.4 0.1 1.8 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Pyr_redox PF00070.27 ABK74825.1 - 0.026 15.1 0.2 0.052 14.1 0.2 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 ABK74825.1 - 0.043 14.0 0.0 0.065 13.4 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NmrA PF05368.13 ABK74825.1 - 0.044 13.3 0.1 0.098 12.2 0.1 1.6 1 1 1 2 2 2 0 NmrA-like family NAD_binding_8 PF13450.6 ABK74825.1 - 0.046 14.0 0.0 0.083 13.1 0.0 1.4 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Rossmann-like PF10727.9 ABK74825.1 - 0.049 13.5 0.9 0.091 12.6 0.9 1.4 1 0 0 1 1 1 0 Rossmann-like domain Pyr_redox_2 PF07992.14 ABK74825.1 - 0.066 12.4 0.2 0.17 11.1 0.0 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.12 ABK74825.1 - 0.2 11.2 0.1 3.8 7.1 0.0 2.3 2 1 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain BPD_transp_1 PF00528.22 ABK74826.1 - 1.3e-19 70.6 18.1 2.4e-19 69.8 18.1 1.3 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component SBP_bac_3 PF00497.20 ABK74827.1 - 3e-59 200.2 0.1 4.1e-59 199.7 0.1 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 ABK74827.1 - 2.9e-06 27.5 0.2 9.7e-06 25.8 0.2 1.8 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site AP_endonuc_2 PF01261.24 ABK74828.1 - 3.4e-21 75.7 0.2 4.5e-21 75.2 0.2 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel AP_endonuc_2_N PF07582.12 ABK74828.1 - 0.065 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 AP endonuclease family 2 C terminus UvrC_HhH_N PF08459.11 ABK74829.1 - 1.7e-49 167.7 0.0 4.3e-49 166.4 0.0 1.7 2 0 0 2 2 2 1 UvrC Helix-hairpin-helix N-terminal HHH_5 PF14520.6 ABK74829.1 - 6.1e-10 39.6 0.1 1.4e-09 38.4 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain GIY-YIG PF01541.24 ABK74829.1 - 8.9e-10 38.7 0.0 1.9e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain UVR PF02151.19 ABK74829.1 - 1.5e-09 37.3 6.4 3.1e-09 36.3 6.4 1.6 1 0 0 1 1 1 1 UvrB/uvrC motif HHH_2 PF12826.7 ABK74829.1 - 3.9e-09 36.5 0.1 1e-08 35.1 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 ABK74829.1 - 2.6e-06 27.0 0.2 9.8e-06 25.2 0.2 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif Methyltr_RsmB-F PF01189.17 ABK74829.1 - 0.0047 16.6 0.1 0.01 15.5 0.1 1.5 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F DUF3701 PF12482.8 ABK74829.1 - 0.22 11.6 1.2 8.5 6.5 0.1 3.1 2 1 1 3 3 3 0 Phage integrase protein Flavin_Reduct PF01613.18 ABK74830.1 - 2.6e-37 128.2 0.0 3.1e-37 128.0 0.0 1.0 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.12 ABK74830.1 - 0.00055 19.8 0.0 0.00079 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF447) MLTR_LBD PF17765.1 ABK74831.1 - 4.3e-47 160.4 5.3 4.3e-47 160.4 5.3 1.9 2 0 0 2 2 2 1 MmyB-like transcription regulator ligand binding domain HTH_31 PF13560.6 ABK74831.1 - 1e-17 64.2 6.5 1e-17 64.2 6.5 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 ABK74831.1 - 3.7e-08 33.3 0.0 9.9e-08 31.9 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 ABK74831.1 - 0.00035 20.9 0.0 0.00073 19.9 0.0 1.5 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_19 PF12844.7 ABK74831.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain MFS_1 PF07690.16 ABK74832.1 - 8.1e-32 110.5 47.6 9.3e-17 61.0 18.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK74832.1 - 8.2e-27 94.2 20.4 1.5e-18 67.0 4.3 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 ABK74832.1 - 6.8e-11 41.4 19.4 1.6e-10 40.2 15.7 2.1 1 1 1 2 2 2 2 MFS/sugar transport protein Lentiviral_Tat PF02998.14 ABK74833.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Lentiviral Tat protein FMN_red PF03358.15 ABK74834.1 - 4.2e-19 68.8 0.0 5.3e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 ABK74834.1 - 0.00041 20.1 0.0 0.00064 19.5 0.0 1.5 1 1 0 1 1 1 1 Flavodoxin-like fold Acetyltransf_1 PF00583.25 ABK74835.1 - 1.7e-13 50.8 0.0 2.2e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ABK74835.1 - 0.00026 20.9 0.0 0.00037 20.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ABK74835.1 - 0.0005 20.4 0.0 0.00071 20.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ABK74835.1 - 0.00085 19.2 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 ABK74835.1 - 0.0051 17.5 0.0 0.0075 17.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ABK74835.1 - 0.053 13.6 0.0 0.093 12.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ABK74835.1 - 0.06 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.6 ABK74835.1 - 0.13 11.9 0.0 0.34 10.6 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain ABC_tran PF00005.27 ABK74836.1 - 1.9e-31 109.4 0.0 2.9e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK74836.1 - 3.4e-12 46.8 0.2 1.1e-08 35.3 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system OB_MalK PF17912.1 ABK74836.1 - 7.7e-05 23.5 0.1 0.00025 21.8 0.1 2.0 1 0 0 1 1 1 1 MalK OB fold domain SMC_N PF02463.19 ABK74836.1 - 0.00026 20.5 0.0 0.0051 16.3 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain CysA_C_terminal PF17850.1 ABK74836.1 - 0.00056 20.4 3.3 0.0019 18.7 0.9 2.7 2 0 0 2 2 2 1 CysA C-terminal regulatory domain TOBE_2 PF08402.10 ABK74836.1 - 0.00087 19.4 0.3 0.0037 17.4 0.3 2.2 1 0 0 1 1 1 1 TOBE domain AAA_22 PF13401.6 ABK74836.1 - 0.0018 18.6 0.1 0.0048 17.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 ABK74836.1 - 0.0035 17.3 0.0 0.0058 16.6 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 ABK74836.1 - 0.0042 17.5 0.3 0.032 14.6 0.3 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ABK74836.1 - 0.0089 16.4 1.0 0.023 15.1 1.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 ABK74836.1 - 0.01 15.4 0.3 0.34 10.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 ABK74836.1 - 0.04 13.8 0.1 0.22 11.4 0.1 2.1 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 ABK74836.1 - 0.055 13.4 0.3 0.35 10.8 0.1 2.2 3 0 0 3 3 3 0 NACHT domain AAA_28 PF13521.6 ABK74836.1 - 0.072 13.3 2.9 0.2 11.9 0.5 2.4 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 ABK74836.1 - 0.14 12.7 0.1 0.23 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ABK74836.1 - 0.18 11.5 1.0 0.63 9.7 0.1 2.3 3 0 0 3 3 3 0 AAA domain Lipase_GDSL_2 PF13472.6 ABK74838.1 - 1.2e-14 55.2 0.0 1.6e-14 54.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ABK74838.1 - 9.1e-05 22.5 0.0 0.00078 19.5 0.0 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Sugar_tr PF00083.24 ABK74839.1 - 6.7e-30 104.3 25.6 2e-22 79.7 3.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ABK74839.1 - 3.9e-29 101.7 33.2 3.9e-29 101.7 33.2 2.6 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 ABK74839.1 - 7.6e-05 21.7 6.8 0.0018 17.2 3.2 2.5 2 1 0 2 2 2 2 MFS_1 like family Peripla_BP_3 PF13377.6 ABK74840.1 - 5.4e-31 108.2 1.4 8.4e-31 107.5 0.4 1.8 3 0 0 3 3 3 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 ABK74840.1 - 1.1e-23 84.1 0.0 1.5e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 ABK74840.1 - 1.8e-14 53.2 0.1 1.4e-13 50.4 0.0 2.2 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 ABK74840.1 - 4.5e-14 52.6 0.0 5.8e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain HTH_1 PF00126.27 ABK74840.1 - 0.0095 15.9 0.0 0.036 14.0 0.0 2.0 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_10 PF04967.12 ABK74840.1 - 0.029 14.2 0.0 0.066 13.0 0.0 1.6 1 0 0 1 1 1 0 HTH DNA binding domain HTH_24 PF13412.6 ABK74840.1 - 0.052 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_3 PF01381.22 ABK74840.1 - 0.077 13.1 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix TrmB PF01978.19 ABK74840.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB TetR_N PF00440.23 ABK74840.1 - 0.13 12.0 0.1 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family HTH_26 PF13443.6 ABK74840.1 - 0.14 12.7 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Hexapep_loop PF18776.1 ABK74840.1 - 0.18 11.5 1.4 0.44 10.2 0.1 2.2 2 0 0 2 2 2 0 Hexapeptide repeat including loop FUR PF01475.19 ABK74841.1 - 1.4e-19 70.4 0.0 1.9e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Ferric uptake regulator family TrmB PF01978.19 ABK74841.1 - 0.0073 16.2 0.0 0.015 15.2 0.0 1.5 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Nudix_N_2 PF14803.6 ABK74841.1 - 0.072 13.0 0.4 0.072 13.0 0.4 1.9 2 0 0 2 2 2 0 Nudix N-terminal Rubredoxin_2 PF18073.1 ABK74841.1 - 1 9.1 4.8 12 5.7 0.6 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain CoA_transf_3 PF02515.17 ABK74842.1 - 2.1e-102 343.0 0.0 2.4e-102 342.8 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Form_Nir_trans PF01226.17 ABK74843.1 - 4.6e-66 222.5 24.9 5.3e-66 222.3 24.9 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter Trp_oprn_chp PF09534.10 ABK74843.1 - 9.2 6.0 12.6 0.083 12.7 4.2 1.9 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) OB_aCoA_assoc PF01796.17 ABK74844.1 - 6.8e-14 51.6 0.7 1.5e-13 50.5 0.7 1.6 1 0 0 1 1 1 1 DUF35 OB-fold domain, acyl-CoA-associated DUF35_N PF12172.8 ABK74844.1 - 6.7e-11 41.8 3.4 1.2e-10 41.0 3.4 1.4 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) ZU5 PF00791.20 ABK74844.1 - 0.065 13.6 0.0 0.2 12.1 0.0 1.7 2 0 0 2 2 2 0 ZU5 domain zf-C4H2 PF10146.9 ABK74844.1 - 2.2 8.6 3.7 3.6 7.8 3.7 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein Virul_fac_BrkB PF03631.15 ABK74845.1 - 3.9e-46 157.8 21.9 4.7e-46 157.5 21.9 1.1 1 0 0 1 1 1 1 Virulence factor BrkB BPD_transp_1 PF00528.22 ABK74846.1 - 4.1e-23 82.1 16.8 4.1e-23 82.1 16.8 1.5 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Gly-zipper_Omp PF13488.6 ABK74846.1 - 0.79 9.8 6.2 14 5.8 0.8 2.8 2 0 0 2 2 2 0 Glycine zipper Gly-zipper_YMGG PF13441.6 ABK74846.1 - 1.5 8.6 6.0 11 5.9 1.0 2.5 2 0 0 2 2 2 0 YMGG-like Gly-zipper FtsX PF02687.21 ABK74846.1 - 2 8.9 26.2 0.053 14.0 6.8 2.9 3 0 0 3 3 3 0 FtsX-like permease family Rick_17kDa_Anti PF05433.15 ABK74846.1 - 8.3 6.4 9.7 11 6.0 1.4 3.0 2 1 1 3 3 3 0 Glycine zipper 2TM domain Glyoxalase PF00903.25 ABK74848.1 - 2.6e-14 53.5 0.0 3.2e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ABK74848.1 - 2.7e-08 34.5 0.0 3.5e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 ABK74848.1 - 3e-07 30.4 0.0 4.5e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain FAD_binding_5 PF00941.21 ABK74849.1 - 7.8e-14 51.8 0.0 1.1e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase NLPC_P60 PF00877.19 ABK74850.1 - 0.0011 19.0 0.1 0.0015 18.5 0.1 1.3 1 1 0 1 1 1 1 NlpC/P60 family Abhydrolase_1 PF00561.20 ABK74851.1 - 7.1e-21 75.0 0.9 7.4e-17 61.8 0.8 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK74851.1 - 7.3e-14 52.9 19.6 1e-13 52.4 19.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK74851.1 - 6.9e-07 28.8 0.6 1.1e-06 28.1 0.6 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 ABK74851.1 - 0.083 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein HTH_30 PF13556.6 ABK74853.1 - 2.5e-17 62.4 0.4 5.7e-17 61.3 0.4 1.6 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain GGDEF_2 PF17853.1 ABK74853.1 - 2e-08 34.5 1.3 2e-08 34.5 1.3 2.9 2 1 0 2 2 2 1 GGDEF-like domain HTH_8 PF02954.19 ABK74853.1 - 0.00044 20.0 0.2 0.0013 18.4 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family HTH_1 PF00126.27 ABK74853.1 - 0.11 12.4 3.2 0.25 11.3 0.0 3.1 3 1 0 3 3 3 0 Bacterial regulatory helix-turn-helix protein, lysR family BMC PF00936.19 ABK74854.1 - 1e-25 89.5 8.4 1.2e-25 89.3 8.4 1.0 1 0 0 1 1 1 1 BMC domain HPTransfase PF10090.9 ABK74854.1 - 0.019 14.8 0.7 0.022 14.6 0.7 1.1 1 0 0 1 1 1 0 Histidine phosphotransferase C-terminal domain Pup PF05639.11 ABK74855.1 - 3.3e-23 82.4 3.3 3.5e-23 82.3 3.3 1.0 1 0 0 1 1 1 1 Pup-like protein YtxH PF12732.7 ABK74855.1 - 0.008 16.7 0.2 0.011 16.3 0.2 1.2 1 0 0 1 1 1 1 YtxH-like protein TH1 PF04858.13 ABK74855.1 - 0.052 12.2 0.3 0.052 12.2 0.3 1.0 1 0 0 1 1 1 0 TH1 protein DUF2470 PF10615.9 ABK74857.1 - 2.3e-14 53.8 0.0 4.1e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Pyrid_oxidase_2 PF13883.6 ABK74857.1 - 2.5e-14 53.6 0.0 3.5e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 ABK74857.1 - 8.2e-13 48.4 0.0 1.3e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF4031 PF13223.6 ABK74857.1 - 0.064 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4031) Peripla_BP_4 PF13407.6 ABK74858.1 - 1.7e-25 90.1 0.0 2.1e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain LacI PF00356.21 ABK74858.1 - 2.4e-09 36.8 0.2 2.3e-08 33.7 0.1 2.6 3 0 0 3 3 3 1 Bacterial regulatory proteins, lacI family HTH_23 PF13384.6 ABK74858.1 - 0.00042 20.0 0.0 0.0012 18.6 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 ABK74858.1 - 0.0088 15.4 0.1 0.038 13.4 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_31 PF13560.6 ABK74858.1 - 0.011 16.0 0.9 0.038 14.3 0.2 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Hydrolase PF00702.26 ABK74858.1 - 0.012 15.9 0.2 0.079 13.2 0.1 2.1 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase HTH_29 PF13551.6 ABK74858.1 - 0.014 15.4 0.0 0.043 13.8 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn helix Sigma70_r4_2 PF08281.12 ABK74858.1 - 0.024 14.3 0.4 0.07 12.8 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_26 PF13443.6 ABK74858.1 - 0.025 15.0 0.0 0.049 14.1 0.0 1.6 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 ABK74858.1 - 0.028 14.0 0.1 0.71 9.5 0.0 2.9 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 ABK74858.1 - 0.033 14.0 0.0 0.088 12.6 0.0 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain MarR_2 PF12802.7 ABK74858.1 - 0.04 13.8 0.1 2.7 7.9 0.0 3.4 3 0 0 3 3 3 0 MarR family Terminase_5 PF06056.12 ABK74858.1 - 0.043 13.7 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_AsnC-type PF13404.6 ABK74858.1 - 0.043 13.6 2.9 0.13 12.1 0.0 3.1 4 0 0 4 4 4 0 AsnC-type helix-turn-helix domain Glyoxalase PF00903.25 ABK74858.1 - 0.076 13.2 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily HMA PF00403.26 ABK74858.1 - 0.084 13.3 0.0 1.4 9.4 0.0 2.6 2 0 0 2 2 2 0 Heavy-metal-associated domain HTH_38 PF13936.6 ABK74858.1 - 0.097 12.5 0.0 0.32 10.8 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_AraC PF00165.23 ABK74858.1 - 0.14 12.3 0.0 0.72 10.0 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family GerE PF00196.19 ABK74858.1 - 0.18 11.4 0.0 0.38 10.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family GFO_IDH_MocA PF01408.22 ABK74864.1 - 1.5e-21 77.4 0.9 2.9e-21 76.5 0.9 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ABK74864.1 - 5.2e-10 39.3 0.0 1.3e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_2 PF03446.15 ABK74864.1 - 0.00056 20.1 0.1 0.0013 18.9 0.1 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DapB_N PF01113.20 ABK74864.1 - 0.00072 19.7 0.3 0.0099 16.0 0.0 2.6 2 1 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus CoA_binding PF02629.19 ABK74864.1 - 0.00078 20.1 0.6 0.002 18.8 0.1 2.0 2 0 0 2 2 2 1 CoA binding domain F420_oxidored PF03807.17 ABK74864.1 - 0.0088 16.6 2.7 0.039 14.5 0.5 2.5 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 ABK74864.1 - 0.012 15.5 1.0 0.069 13.0 0.2 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 ABK74864.1 - 0.027 13.9 0.3 0.32 10.4 0.1 2.5 2 1 1 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 ABK74864.1 - 0.1 12.6 1.7 2 8.4 0.2 2.3 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 ABK74864.1 - 0.12 12.6 5.2 1 9.6 0.1 2.8 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain ATP-grasp PF02222.22 ABK74865.1 - 3.3e-36 124.4 0.0 5.2e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 ABK74865.1 - 0.00048 19.7 0.0 0.0008 19.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_5 PF13549.6 ABK74865.1 - 0.0047 16.4 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Epimerase PF01370.21 ABK74865.1 - 0.026 14.0 0.1 0.043 13.3 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ATP-grasp_3 PF02655.14 ABK74865.1 - 0.054 13.5 0.0 0.69 9.9 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp domain RmlD_sub_bind PF04321.17 ABK74865.1 - 0.13 11.3 0.1 0.26 10.3 0.1 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain Pyr_redox PF00070.27 ABK74865.1 - 0.15 12.6 0.2 0.39 11.3 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Dala_Dala_lig_C PF07478.13 ABK74865.1 - 0.23 10.9 0.0 0.94 9.0 0.0 1.8 1 1 0 1 1 1 0 D-ala D-ala ligase C-terminus Peptidase_M16_C PF05193.21 ABK74866.1 - 6.3e-42 143.7 0.0 9.5e-42 143.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 ABK74866.1 - 1.5e-36 125.7 0.0 2.8e-36 124.8 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) CsbD PF05532.12 ABK74867.1 - 1.3e-15 57.0 5.6 1.4e-15 56.9 5.6 1.0 1 0 0 1 1 1 1 CsbD-like Aldo_ket_red PF00248.21 ABK74868.1 - 1.1e-68 231.7 0.0 1.2e-68 231.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Myco_19_kDa PF05481.12 ABK74869.1 - 4.4e-34 117.2 5.7 4.4e-34 117.2 5.7 1.6 2 0 0 2 2 2 1 Mycobacterium 19 kDa lipoprotein antigen tRNA-synt_2d PF01409.20 ABK74870.1 - 1e-95 319.9 0.0 1.2e-95 319.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) Phe_tRNA-synt_N PF02912.18 ABK74870.1 - 1.3e-14 53.9 0.6 2.2e-14 53.1 0.6 1.4 1 0 0 1 1 1 1 Aminoacyl tRNA synthetase class II, N-terminal domain tRNA_synthFbeta PF17759.1 ABK74870.1 - 0.024 14.1 0.0 0.2 11.1 0.0 2.1 1 1 0 1 1 1 0 Phenylalanyl tRNA synthetase beta chain CLM domain Aldedh PF00171.22 ABK74870.1 - 0.38 9.2 1.8 0.53 8.7 1.8 1.1 1 0 0 1 1 1 0 Aldehyde dehydrogenase family adh_short_C2 PF13561.6 ABK74871.1 - 5.5e-46 157.0 0.0 6.8e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK74871.1 - 3.2e-33 114.8 0.0 5.3e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK74871.1 - 7.3e-07 29.3 0.0 2.6e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK74871.1 - 1.8e-05 24.3 0.0 2.8e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DNA_pol_lambd_f PF10391.9 ABK74871.1 - 0.012 15.4 0.0 0.034 14.0 0.0 1.7 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda HHH_5 PF14520.6 ABK74871.1 - 0.047 14.3 0.2 0.12 13.0 0.2 1.7 1 1 0 1 1 1 0 Helix-hairpin-helix domain 3Beta_HSD PF01073.19 ABK74871.1 - 0.082 11.9 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding PF00501.28 ABK74872.1 - 5.2e-83 279.0 0.0 6.2e-83 278.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK74872.1 - 3.4e-21 76.0 0.2 1.3e-20 74.1 0.4 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GTP_EFTU PF00009.27 ABK74873.1 - 3e-24 85.7 0.0 2e-23 83.0 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SelB-wing_3 PF09107.11 ABK74873.1 - 4.8e-12 45.3 0.0 4.8e-12 45.3 0.0 2.3 3 0 0 3 3 3 1 Elongation factor SelB, winged helix MMR_HSR1 PF01926.23 ABK74873.1 - 7.3e-07 29.3 0.0 1.3e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 ABK74873.1 - 2.6e-05 24.5 2.0 7.1e-05 23.1 2.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 AbiEi_4 PF13338.6 ABK74873.1 - 0.0056 16.8 1.3 0.18 12.0 0.1 3.4 2 0 0 2 2 2 1 Transcriptional regulator, AbiEi antitoxin FeoB_N PF02421.18 ABK74873.1 - 0.062 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.10 ABK74873.1 - 0.064 12.7 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Sigma70_r4_2 PF08281.12 ABK74874.1 - 2.5e-12 46.3 0.2 4e-12 45.6 0.2 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 ABK74874.1 - 3.1e-12 46.1 2.2 6.3e-12 45.1 0.3 2.3 2 0 0 2 2 2 1 Sigma-70 region 2 SnoaL_2 PF12680.7 ABK74874.1 - 1.4e-06 28.9 3.7 4.4e-06 27.3 0.5 2.3 2 0 0 2 2 2 1 SnoaL-like domain Sigma70_r4 PF04545.16 ABK74874.1 - 0.00012 21.5 0.1 0.0002 20.8 0.1 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 SnoaL PF07366.12 ABK74874.1 - 0.0099 15.7 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_3 PF13474.6 ABK74874.1 - 0.035 14.4 0.0 0.089 13.1 0.0 1.7 1 0 0 1 1 1 0 SnoaL-like domain DUF4440 PF14534.6 ABK74874.1 - 0.076 13.4 1.1 0.1 13.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) Myco_19_kDa PF05481.12 ABK74876.1 - 2.2e-29 102.1 2.3 3e-29 101.7 2.3 1.2 1 0 0 1 1 1 1 Mycobacterium 19 kDa lipoprotein antigen MotA_activ PF09114.10 ABK74876.1 - 0.09 12.9 0.2 0.23 11.6 0.2 1.6 1 1 0 1 1 1 0 Transcription factor MotA, activation domain SSF PF00474.17 ABK74877.1 - 4.7e-31 108.1 29.7 7.1e-31 107.5 29.7 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family MlaD PF02470.20 ABK74878.1 - 1.4e-11 44.5 0.0 2.5e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 MlaD protein Mce4_CUP1 PF11887.8 ABK74878.1 - 0.00067 19.2 2.2 0.0014 18.2 2.1 1.5 1 1 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative Syntaxin_2 PF14523.6 ABK74878.1 - 0.018 15.4 4.5 0.13 12.6 4.5 2.1 1 1 0 1 1 1 0 Syntaxin-like protein Sec15 PF04091.12 ABK74878.1 - 0.036 13.5 0.2 0.05 13.0 0.2 1.1 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like DUF948 PF06103.11 ABK74878.1 - 0.041 14.1 0.9 0.13 12.5 0.5 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1043 PF06295.12 ABK74878.1 - 0.049 13.6 1.2 0.2 11.6 1.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) BORCS7 PF16088.5 ABK74878.1 - 0.16 12.2 0.2 0.9 9.8 0.1 2.0 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 7 DUF1664 PF07889.12 ABK74878.1 - 0.25 11.4 0.2 1.2 9.1 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) UPF0184 PF03670.13 ABK74878.1 - 0.27 11.6 1.9 4.6 7.7 0.6 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) RmuC PF02646.16 ABK74878.1 - 0.35 10.0 1.6 1.5 7.9 0.5 2.0 1 1 0 2 2 2 0 RmuC family Baculo_PEP_C PF04513.12 ABK74878.1 - 0.42 10.7 10.1 2.9 7.9 4.0 2.5 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus LPAM_2 PF13627.6 ABK74878.1 - 1.3 9.0 3.7 3.1 7.8 3.7 1.7 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site tRNA-synt_1 PF00133.22 ABK74879.1 - 7.3e-197 655.3 0.0 3.4e-148 494.6 0.0 2.9 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 ABK74879.1 - 1.7e-40 138.5 0.0 2.6e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 ABK74879.1 - 3e-19 69.0 0.0 1.3e-06 27.4 0.0 4.2 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 ABK74879.1 - 1.6e-06 27.8 0.2 6.2e-05 22.6 0.1 2.2 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 ABK74879.1 - 0.00027 20.4 0.0 0.5 9.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 ABK74879.1 - 0.0046 15.9 0.0 0.0078 15.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (K) DALR_1 PF05746.15 ABK74879.1 - 0.038 14.2 0.1 0.075 13.2 0.1 1.4 1 0 0 1 1 1 0 DALR anticodon binding domain Acyl-CoA_dh_1 PF00441.24 ABK74880.1 - 3e-27 95.7 0.8 5.5e-27 94.8 0.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK74880.1 - 6.8e-23 81.5 0.5 3.4e-22 79.2 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ABK74880.1 - 3.4e-13 50.0 0.1 9e-13 48.7 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK74880.1 - 1.3e-11 44.5 0.0 2.5e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain p450 PF00067.22 ABK74881.1 - 2.9e-19 69.2 0.1 5.1e-16 58.5 0.1 2.7 2 1 0 2 2 2 1 Cytochrome P450 MTES_1575 PF18741.1 ABK74883.1 - 7.6e-05 22.8 0.3 0.00014 22.0 0.3 1.4 1 0 0 1 1 1 1 REase_MTES_1575 AbiEi_1 PF09407.10 ABK74883.1 - 0.016 15.5 0.2 0.032 14.5 0.2 1.5 1 0 0 1 1 1 0 AbiEi antitoxin C-terminal domain DUF559 PF04480.12 ABK74883.1 - 0.05 13.5 0.1 0.087 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF559) CBS PF00571.28 ABK74883.1 - 0.071 13.6 1.4 1.5 9.3 0.0 3.3 4 0 0 4 4 4 0 CBS domain Oxidored_molyb PF00174.19 ABK74884.1 - 1.9e-36 125.3 0.0 2.8e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Big_7 PF17957.1 ABK74884.1 - 2.2e-05 25.1 0.1 5.8e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Bacterial Ig domain Y_Y_Y PF07495.13 ABK74884.1 - 0.077 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Y_Y_Y domain DUF4064 PF13273.6 ABK74884.1 - 0.13 12.5 1.4 27 5.1 0.0 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF4064) ThrE PF06738.12 ABK74884.1 - 0.26 10.6 3.8 0.38 10.1 0.7 2.3 2 0 0 2 2 2 0 Putative threonine/serine exporter Ammonium_transp PF00909.21 ABK74884.1 - 1.1 7.9 5.1 1.7 7.2 5.1 1.4 1 0 0 1 1 1 0 Ammonium Transporter Family DUF3040 PF11239.8 ABK74884.1 - 8.9 6.7 12.8 22 5.4 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Chorismate_bind PF00425.18 ABK74885.1 - 4.1e-95 318.2 0.0 1e-94 316.9 0.0 1.6 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 ABK74885.1 - 5.9e-35 120.5 0.0 4.2e-32 111.3 0.0 3.0 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region HTH_Tnp_1 PF01527.20 ABK74886.1 - 5.2e-05 23.5 1.1 6.3e-05 23.2 1.1 1.2 1 0 0 1 1 1 1 Transposase HTH_17 PF12728.7 ABK74886.1 - 0.018 15.2 0.1 0.042 14.1 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain Acetyltransf_CG PF14542.6 ABK74887.1 - 1.4e-23 82.8 0.1 1.6e-23 82.6 0.1 1.1 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 ABK74887.1 - 0.007 16.3 0.0 0.0071 16.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ABK74887.1 - 0.092 13.0 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ABK74887.1 - 0.1 13.1 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 ABK74889.1 - 2.7e-51 174.6 57.7 1.1e-25 90.3 29.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK74889.1 - 5.4e-10 38.7 38.5 3.6e-06 26.1 11.8 3.3 3 1 1 4 4 4 2 Sugar (and other) transporter MFS_2 PF13347.6 ABK74889.1 - 2.1e-07 29.9 31.2 7e-05 21.6 13.4 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 ABK74889.1 - 3.8e-05 22.7 11.5 3.8e-05 22.7 11.5 2.2 1 1 1 2 2 2 2 MFS_1 like family MFS_3 PF05977.13 ABK74889.1 - 3.8e-05 22.3 17.4 3.8e-05 22.3 17.4 2.1 1 1 1 2 2 2 2 Transmembrane secretion effector MFS_4 PF06779.14 ABK74889.1 - 0.00031 20.2 41.5 0.00042 19.7 41.5 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB PTR2 PF00854.21 ABK74889.1 - 0.098 11.5 11.5 0.017 14.0 4.2 2.8 3 1 0 3 3 3 0 POT family APH PF01636.23 ABK74890.1 - 3.1e-19 69.9 3.3 4.4e-19 69.3 3.3 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Yop-YscD_cpl PF16697.5 ABK74891.1 - 6.8e-16 58.4 0.0 8.8e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA PF00498.26 ABK74891.1 - 3e-14 53.1 0.0 4.8e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 FHA domain TauE PF01925.19 ABK74892.1 - 2.7e-50 171.2 52.4 2.7e-50 171.2 52.4 1.7 1 1 1 2 2 2 1 Sulfite exporter TauE/SafE Rieske PF00355.26 ABK74893.1 - 2.4e-10 40.2 0.0 4.5e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain AidB_N PF18158.1 ABK74895.1 - 9.7e-55 184.8 0.6 3.5e-54 183.0 0.0 2.1 2 1 1 3 3 3 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 ABK74895.1 - 2e-29 102.7 2.9 3.7e-29 101.9 2.9 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK74895.1 - 7e-15 55.0 0.0 1.3e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ABK74895.1 - 4.5e-10 39.9 0.5 4.5e-10 39.9 0.5 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Peptidase_M48 PF01435.18 ABK74896.1 - 5.9e-33 114.3 0.0 9e-32 110.4 0.0 2.2 2 0 0 2 2 2 1 Peptidase family M48 Peptidase_M56 PF05569.11 ABK74896.1 - 0.00042 19.6 0.0 0.00059 19.1 0.0 1.1 1 0 0 1 1 1 1 BlaR1 peptidase M56 Peptidase_M78 PF06114.13 ABK74896.1 - 0.056 13.4 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 IrrE N-terminal-like domain DUF4157 PF13699.6 ABK74896.1 - 0.079 13.2 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4157) LysR_substrate PF03466.20 ABK74898.1 - 2.1e-25 89.4 8.6 2.7e-25 89.0 8.6 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 ABK74898.1 - 1.3e-14 53.9 0.4 3e-14 52.7 0.4 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 ABK74898.1 - 0.0099 15.7 0.3 0.028 14.2 0.3 1.8 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_23 PF13384.6 ABK74898.1 - 0.016 15.0 0.3 0.076 12.8 0.1 2.2 2 0 0 2 2 2 0 Homeodomain-like domain HTH_8 PF02954.19 ABK74898.1 - 0.034 13.9 0.1 0.075 12.8 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family HTH_11 PF08279.12 ABK74898.1 - 0.039 13.9 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 HTH domain HTH_24 PF13412.6 ABK74898.1 - 0.096 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding YccF PF03733.13 ABK74899.1 - 2.5e-35 121.0 30.8 1.6e-18 67.1 15.6 2.1 2 0 0 2 2 2 2 Inner membrane component domain EBV-NA1 PF02905.14 ABK74899.1 - 0.089 12.6 0.5 3.7 7.4 0.1 2.1 1 1 1 2 2 2 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain DUF2189 PF09955.9 ABK74899.1 - 0.13 12.5 8.7 0.86 9.9 0.8 2.2 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2189) PLDc_2 PF13091.6 ABK74900.1 - 0.0064 16.4 0.0 0.014 15.3 0.0 1.5 2 0 0 2 2 2 1 PLD-like domain Abhydrolase_6 PF12697.7 ABK74900.1 - 0.34 11.5 3.8 0.31 11.6 1.3 2.2 1 1 1 2 2 2 0 Alpha/beta hydrolase family DUF1214 PF06742.11 ABK74901.1 - 0.0045 17.4 0.2 0.54 10.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1214) Peptidase_S9 PF00326.21 ABK74902.1 - 1e-50 172.2 0.0 2.7e-50 170.8 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 ABK74902.1 - 7.1e-14 51.7 0.0 5e-08 32.5 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 ABK74902.1 - 5.5e-13 49.1 0.0 1.2e-07 31.6 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 ABK74902.1 - 1.2e-12 48.0 0.1 2.5e-09 37.2 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK74902.1 - 9.9e-09 36.1 2.4 9.9e-09 36.1 2.4 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 ABK74902.1 - 3.3e-05 23.8 0.0 0.31 10.8 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase DLH PF01738.18 ABK74902.1 - 3.3e-05 23.5 0.0 0.00014 21.5 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family DUF2920 PF11144.8 ABK74902.1 - 0.00046 19.5 0.0 0.17 11.0 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2920) BAAT_C PF08840.11 ABK74902.1 - 0.0013 18.7 0.0 0.51 10.2 0.0 2.2 1 1 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 ABK74902.1 - 0.0016 18.3 0.0 0.0037 17.1 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 ABK74902.1 - 0.0027 17.8 0.0 0.0068 16.5 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein FSH1 PF03959.13 ABK74902.1 - 0.0069 16.1 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) LIP PF03583.14 ABK74902.1 - 0.013 14.9 0.0 0.15 11.4 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase Esterase PF00756.20 ABK74902.1 - 0.033 13.8 0.1 0.076 12.7 0.0 1.6 2 0 0 2 2 2 0 Putative esterase AXE1 PF05448.12 ABK74902.1 - 0.074 11.7 0.0 0.16 10.6 0.0 1.6 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) PGM_PMM_I PF02878.16 ABK74904.1 - 1.4e-30 105.8 0.0 3e-30 104.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 ABK74904.1 - 3.6e-25 88.4 0.0 6.7e-25 87.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 ABK74904.1 - 4.6e-21 75.4 0.0 9.7e-21 74.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 ABK74904.1 - 5.5e-12 45.7 0.0 1.1e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Sugar_tr PF00083.24 ABK74905.1 - 1.5e-35 123.0 24.0 8.3e-33 113.9 24.0 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ABK74905.1 - 3.5e-30 105.1 59.8 4.2e-18 65.4 31.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ABK74905.1 - 3.8e-07 29.0 12.0 3.8e-07 29.0 12.0 2.5 2 1 1 3 3 3 2 MFS/sugar transport protein Acetate_kinase PF00871.17 ABK74906.1 - 1.2e-134 449.0 0.0 1e-132 442.5 0.0 2.0 1 1 0 1 1 1 1 Acetokinase family Gram_pos_anchor PF00746.21 ABK74907.1 - 1.7 8.6 0.0 1.7 8.6 0.0 2.8 3 0 0 3 3 3 0 LPXTG cell wall anchor motif DUF1467 PF07330.12 ABK74907.1 - 1.8 8.6 8.4 2.2 8.3 0.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1467) DUF4231 PF14015.6 ABK74907.1 - 2.9 8.4 8.1 8.8 6.9 5.2 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) Adenylsucc_synt PF00709.21 ABK74908.1 - 1.9e-173 577.3 0.0 2.1e-173 577.1 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase TetR_C_11 PF16859.5 ABK74909.1 - 4e-29 101.2 7.5 4e-29 101.2 7.5 1.7 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK74909.1 - 3.7e-09 36.2 0.0 7.4e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_7 PF14246.6 ABK74909.1 - 0.00012 22.1 0.1 0.00029 20.9 0.1 1.6 1 1 0 1 1 1 1 AefR-like transcriptional repressor, C-terminal domain TetR_C_9 PF14514.6 ABK74909.1 - 0.011 15.9 0.2 0.033 14.3 0.2 1.7 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TetR_C_29 PF17938.1 ABK74909.1 - 0.037 14.1 0.1 0.078 13.1 0.1 1.5 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain ABATE PF07336.11 ABK74910.1 - 1.8e-14 54.5 14.7 2.5e-14 54.0 14.7 1.2 1 0 0 1 1 1 1 Putative stress-induced transcription regulator zf-CGNR PF11706.8 ABK74910.1 - 1.4e-10 40.8 6.9 2.2e-10 40.2 6.9 1.3 1 0 0 1 1 1 1 CGNR zinc finger DapB_N PF01113.20 ABK74911.1 - 1.5e-07 31.6 0.0 2.5e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 ABK74911.1 - 0.075 13.9 0.0 0.13 13.1 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Metal_hydrol PF10118.9 ABK74913.1 - 5.5e-39 134.4 3.1 6.9e-39 134.1 3.1 1.1 1 0 0 1 1 1 1 Predicted metal-dependent hydrolase COX2 PF00116.20 ABK74914.1 - 8.7e-14 51.4 0.2 2.5e-12 46.7 0.0 2.2 2 0 0 2 2 2 1 Cytochrome C oxidase subunit II, periplasmic domain ABC2_membrane_3 PF12698.7 ABK74914.1 - 0.049 12.7 1.4 0.074 12.2 1.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2062 PF09835.9 ABK74914.1 - 0.71 9.7 4.1 2.7 7.8 0.5 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) Acetyltransf_5 PF13444.6 ABK74915.1 - 1.4e-29 102.7 0.0 2.2e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Autoind_synth PF00765.17 ABK74915.1 - 0.00027 20.5 0.0 0.00051 19.6 0.0 1.4 1 1 0 1 1 1 1 Autoinducer synthase GSH-S_ATP PF02955.16 ABK74916.1 - 0.03 13.7 0.0 0.063 12.7 0.0 1.4 2 0 0 2 2 2 0 Prokaryotic glutathione synthetase, ATP-grasp domain Nudix_N PF12535.8 ABK74917.1 - 2e-15 56.1 0.5 3.1e-15 55.5 0.5 1.3 1 0 0 1 1 1 1 Hydrolase of X-linked nucleoside diphosphate N terminal NUDIX PF00293.28 ABK74917.1 - 5.7e-15 55.5 0.2 1.3e-14 54.4 0.1 1.5 2 0 0 2 2 2 1 NUDIX domain Amidase PF01425.21 ABK74918.1 - 5.2e-76 256.4 3.1 7.6e-76 255.9 3.1 1.1 1 0 0 1 1 1 1 Amidase TetR_N PF00440.23 ABK74920.1 - 4.8e-13 48.7 0.6 2.3e-12 46.5 0.4 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_13 PF16925.5 ABK74920.1 - 3.5e-05 23.7 0.0 0.0014 18.6 0.0 2.2 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_31 PF17940.1 ABK74920.1 - 0.0037 17.5 3.3 0.0084 16.3 2.5 2.0 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain DDE_Tnp_ISL3 PF01610.17 ABK74921.1 - 1.6e-64 217.9 0.0 2.1e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Transposase zf-ISL3 PF14690.6 ABK74921.1 - 1.1e-09 38.8 4.6 1.8e-09 38.1 2.5 2.5 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HTH_Tnp_ISL3 PF13542.6 ABK74921.1 - 2.4e-08 33.2 1.6 7e-08 31.8 1.6 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 AMP-binding PF00501.28 ABK74922.1 - 8.9e-100 334.2 0.0 1.2e-99 333.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK74922.1 - 5.8e-23 81.7 0.5 2e-22 79.9 0.6 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.25 ABK74924.1 - 7.9e-37 127.1 0.0 1.1e-36 126.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ABK74924.1 - 4.6e-22 78.5 0.0 5.9e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ABK74924.1 - 0.0007 18.5 0.0 0.001 18.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ABK74924.1 - 0.0092 15.9 0.3 0.057 13.3 0.3 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family HisKA_3 PF07730.13 ABK74924.1 - 0.014 15.9 0.0 0.12 12.9 0.0 2.4 2 0 0 2 2 2 0 Histidine kinase Kdo PF06293.14 ABK74924.1 - 0.048 13.0 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pex14_N PF04695.13 ABK74924.1 - 0.37 11.4 6.5 0.19 12.4 1.5 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PhaG_MnhG_YufB PF03334.14 ABK74925.1 - 2.8e-22 78.8 7.5 3.4e-22 78.5 7.5 1.1 1 0 0 1 1 1 1 Na+/H+ antiporter subunit TPPK_C PF12555.8 ABK74925.1 - 0.34 11.0 0.0 0.34 11.0 0.0 2.5 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal BPD_transp_1 PF00528.22 ABK74926.1 - 1.1e-27 97.0 12.8 1.1e-27 97.0 12.8 1.7 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Romo1 PF10247.9 ABK74926.1 - 0.011 16.1 0.7 0.042 14.2 0.7 2.0 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 FA_desaturase PF00487.24 ABK74927.1 - 1.6e-26 93.7 8.1 1e-24 87.7 8.1 2.2 1 1 0 1 1 1 1 Fatty acid desaturase Guanylate_cyc_2 PF09778.9 ABK74927.1 - 0.031 13.6 0.4 0.05 13.0 0.4 1.2 1 0 0 1 1 1 0 Guanylylate cyclase HTH_1 PF00126.27 ABK74928.1 - 9.4e-20 70.3 0.8 2.8e-19 68.8 0.8 1.9 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 ABK74928.1 - 3.5e-10 39.6 0.7 3.5e-10 39.6 0.7 1.6 2 0 0 2 2 2 1 LysR substrate binding domain HTH_24 PF13412.6 ABK74928.1 - 0.077 12.6 0.1 0.17 11.5 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_5 PF01022.20 ABK74929.1 - 2.6e-18 65.6 0.0 5.3e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 ABK74929.1 - 3.4e-14 52.6 2.5 8e-14 51.5 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 ABK74929.1 - 0.00047 20.0 0.2 0.00047 20.0 0.2 2.1 3 0 0 3 3 3 1 MarR family TrmB PF01978.19 ABK74929.1 - 0.00081 19.2 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 ABK74929.1 - 0.0017 17.8 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Rrf2 PF02082.20 ABK74929.1 - 0.002 18.5 0.0 0.0041 17.4 0.0 1.5 1 1 0 1 1 1 1 Transcriptional regulator HTH_Crp_2 PF13545.6 ABK74929.1 - 0.0063 16.5 0.0 0.015 15.2 0.0 1.7 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain Fe_dep_repress PF01325.19 ABK74929.1 - 0.02 15.1 0.0 0.033 14.4 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain MarR PF01047.22 ABK74929.1 - 0.026 14.5 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_IclR PF09339.10 ABK74929.1 - 0.029 14.2 0.3 0.06 13.2 0.1 1.7 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_1 PF00126.27 ABK74929.1 - 0.057 13.4 0.4 0.49 10.4 0.0 2.5 3 1 1 4 4 4 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_34 PF13601.6 ABK74929.1 - 0.077 13.2 0.0 0.33 11.2 0.0 1.9 2 0 0 2 2 2 0 Winged helix DNA-binding domain RepL PF05732.11 ABK74929.1 - 0.091 12.2 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) HSP20 PF00011.21 ABK74930.1 - 2.1e-24 85.6 0.0 2.6e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ABK74930.1 - 6.8e-11 41.6 0.0 1e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA CMD PF02627.20 ABK74931.1 - 9.2e-17 60.9 0.0 1.8e-08 34.3 0.0 2.3 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family SfLAP PF11139.8 ABK74932.1 - 5.5e-62 209.0 22.7 6.2e-62 208.8 22.7 1.0 1 0 0 1 1 1 1 Sap, sulfolipid-1-addressing protein DUF2127 PF09900.9 ABK74932.1 - 0.0075 16.5 1.2 0.0075 16.5 1.2 2.7 2 1 1 3 3 3 1 Predicted membrane protein (DUF2127) DUF981 PF06168.11 ABK74932.1 - 0.016 15.2 11.6 1.3 8.9 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF981) YtpI PF14007.6 ABK74932.1 - 0.043 14.0 0.2 16 5.8 0.4 2.7 2 0 0 2 2 2 0 YtpI-like protein Sugar_tr PF00083.24 ABK74933.1 - 2.1e-30 106.0 22.2 2.4e-26 92.6 6.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ABK74933.1 - 2.1e-29 102.6 51.1 4.1e-18 65.4 27.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4131 PF13567.6 ABK74933.1 - 0.084 12.5 0.1 0.084 12.5 0.1 4.0 3 1 1 5 5 5 0 Domain of unknown function (DUF4131) DUF421 PF04239.12 ABK74935.1 - 7.4e-13 48.2 0.0 1e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF421) OpuAC PF04069.12 ABK74936.1 - 7.8e-29 101.0 0.0 9.1e-29 100.8 0.0 1.0 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system ECH_1 PF00378.20 ABK74938.1 - 3.2e-50 170.8 0.6 3.6e-50 170.6 0.6 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK74938.1 - 4.5e-31 108.6 0.7 5.4e-31 108.3 0.7 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase T3SS_needle_E PF08988.10 ABK74938.1 - 0.18 12.0 0.9 0.81 9.9 0.0 2.3 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle 4HBT_3 PF13622.6 ABK74939.1 - 1.9e-29 103.7 2.3 2.2e-29 103.5 2.3 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF2561 PF10812.8 ABK74940.1 - 3.1e-55 187.5 15.7 4.5e-54 183.7 15.7 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2561) Phage_holin_3_6 PF07332.11 ABK74940.1 - 5e-05 23.3 1.5 5e-05 23.3 1.5 2.2 2 0 0 2 2 2 1 Putative Actinobacterial Holin-X, holin superfamily III INSIG PF07281.12 ABK74940.1 - 0.051 13.2 0.1 0.065 12.9 0.1 1.3 1 0 0 1 1 1 0 Insulin-induced protein (INSIG) Saf_2TM PF18303.1 ABK74940.1 - 0.089 12.4 0.2 0.23 11.0 0.0 1.7 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain DUF5336 PF17270.2 ABK74940.1 - 1.6 8.3 10.5 16 5.1 6.5 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5336) SepZ PF06066.11 ABK74940.1 - 8.2 6.7 10.1 2.2 8.6 2.7 2.3 2 1 0 2 2 2 0 SepZ DeoRC PF00455.22 ABK74941.1 - 3.5e-42 144.0 2.8 4.6e-42 143.7 2.8 1.1 1 0 0 1 1 1 1 DeoR C terminal sensor domain HTH_DeoR PF08220.12 ABK74941.1 - 5.5e-16 58.1 0.4 1.3e-15 56.9 0.4 1.6 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_20 PF12840.7 ABK74941.1 - 7.5e-07 29.1 3.2 9.3e-06 25.6 2.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_11 PF08279.12 ABK74941.1 - 2.4e-06 27.4 0.3 4.6e-06 26.5 0.3 1.5 1 0 0 1 1 1 1 HTH domain HTH_5 PF01022.20 ABK74941.1 - 2.2e-05 24.2 0.8 5e-05 23.1 0.6 1.7 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 ABK74941.1 - 0.00012 21.5 1.3 0.00035 20.1 0.6 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding NBD_C PF17042.5 ABK74941.1 - 0.00032 21.3 2.1 0.0017 18.9 1.6 2.2 1 1 1 2 2 2 1 Nucleotide-binding C-terminal domain MarR_2 PF12802.7 ABK74941.1 - 0.00046 20.0 1.9 0.00046 20.0 1.9 1.9 2 0 0 2 2 2 1 MarR family GntR PF00392.21 ABK74941.1 - 0.0014 18.2 1.2 0.0034 17.0 0.3 2.0 1 1 1 2 2 2 1 Bacterial regulatory proteins, gntR family MarR PF01047.22 ABK74941.1 - 0.0038 17.1 0.4 0.0085 16.0 0.4 1.5 1 0 0 1 1 1 1 MarR family Put_DNA-bind_N PF06971.13 ABK74941.1 - 0.0045 17.0 0.5 0.011 15.7 0.5 1.7 1 0 0 1 1 1 1 Putative DNA-binding protein N-terminus HTH_39 PF14090.6 ABK74941.1 - 0.0079 15.9 0.1 0.021 14.6 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain Fe_dep_repress PF01325.19 ABK74941.1 - 0.015 15.5 0.0 0.033 14.4 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain TFIIE_alpha PF02002.17 ABK74941.1 - 0.018 14.9 0.2 0.097 12.5 0.0 2.0 2 0 0 2 2 2 0 TFIIE alpha subunit HTH_27 PF13463.6 ABK74941.1 - 0.02 15.4 0.4 0.043 14.3 0.4 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_Mga PF08280.11 ABK74941.1 - 0.028 14.4 0.1 0.052 13.6 0.1 1.3 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain Rrf2 PF02082.20 ABK74941.1 - 0.061 13.7 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 Transcriptional regulator HTH_12 PF08461.10 ABK74941.1 - 0.064 13.2 0.1 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain Mga PF05043.13 ABK74941.1 - 0.084 13.5 0.0 0.15 12.7 0.0 1.3 1 0 0 1 1 1 0 Mga helix-turn-helix domain PaaX PF07848.12 ABK74941.1 - 0.11 12.7 0.9 0.29 11.4 0.2 2.1 2 0 0 2 2 2 0 PaaX-like protein HTH_IclR PF09339.10 ABK74941.1 - 0.16 11.8 2.5 0.38 10.6 2.5 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain DprA_WH PF17782.1 ABK74941.1 - 2.9 8.1 8.0 0.13 12.3 1.2 2.3 3 0 0 3 3 2 0 DprA winged helix domain Amidohydro_1 PF01979.20 ABK74942.1 - 8.2e-50 170.0 0.0 9.4e-50 169.8 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ABK74942.1 - 1.4e-15 57.7 5.4 8.7e-12 45.3 2.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family Pyrophosphatase PF00719.19 ABK74943.1 - 1.5e-54 184.1 0.0 1.7e-54 183.9 0.0 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase InPase PF18823.1 ABK74943.1 - 0.021 14.6 0.1 0.064 12.9 0.0 1.9 2 1 0 2 2 2 0 Inorganic Pyrophosphatase Alk_phosphatase PF00245.20 ABK74944.1 - 6.2e-117 391.1 4.5 8.6e-117 390.6 4.5 1.2 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 ABK74944.1 - 6.4e-06 25.7 2.6 6.5e-05 22.4 1.9 2.3 2 1 0 2 2 2 1 Metalloenzyme superfamily Sulfatase PF00884.23 ABK74944.1 - 0.0018 17.7 1.8 0.13 11.6 1.8 2.6 1 1 0 1 1 1 1 Sulfatase Pribosyltran PF00156.27 ABK74945.1 - 2.8e-21 75.7 0.0 1e-20 73.8 0.0 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 ABK74945.1 - 0.00015 21.3 0.0 0.00023 20.6 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 ABK74945.1 - 0.0017 17.9 0.0 0.014 14.9 0.0 2.0 2 0 0 2 2 2 1 Phosphoribosyl transferase Pkinase PF00069.25 ABK74946.1 - 2.3e-40 138.7 0.0 2.8e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ABK74946.1 - 2.2e-20 73.0 0.0 2.7e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ABK74946.1 - 4e-07 30.2 1.8 0.0035 17.3 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ABK74946.1 - 5.3e-05 22.2 0.0 6.5e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 ABK74946.1 - 0.0024 17.3 0.0 0.0035 16.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 ABK74946.1 - 0.029 14.0 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Ammonium_transp PF00909.21 ABK74947.1 - 4.7e-115 384.5 45.4 5.3e-115 384.3 45.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Leu_Phe_trans PF03588.14 ABK74947.1 - 3.4 7.2 4.8 1.1 8.7 0.1 2.3 3 0 0 3 3 3 0 Leucyl/phenylalanyl-tRNA protein transferase Sigma70_r2 PF04542.14 ABK74948.1 - 2.1e-18 65.8 0.4 4.5e-18 64.8 0.4 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 ABK74948.1 - 1.2e-13 50.5 0.5 3e-13 49.2 0.4 1.8 1 1 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 ABK74948.1 - 4e-09 35.9 1.1 9.5e-09 34.6 1.1 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 ABK74948.1 - 0.013 15.4 0.4 0.019 14.9 0.4 1.3 1 1 0 1 1 1 0 ECF sigma factor GerE PF00196.19 ABK74948.1 - 0.028 13.9 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_23 PF13384.6 ABK74948.1 - 0.04 13.7 0.5 0.1 12.4 0.0 1.9 1 1 1 2 2 2 0 Homeodomain-like domain HTH_38 PF13936.6 ABK74948.1 - 0.059 13.1 0.1 0.059 13.1 0.1 2.0 3 0 0 3 3 3 0 Helix-turn-helix domain Amino_oxidase PF01593.24 ABK74949.1 - 7.5e-44 150.8 0.2 8.7e-44 150.5 0.2 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 ABK74949.1 - 1.1e-14 54.8 11.4 6.6e-14 52.3 11.4 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ABK74949.1 - 3.5e-13 49.6 0.3 1e-12 48.1 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ABK74949.1 - 1.5e-09 37.1 0.0 0.00047 19.0 0.2 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 ABK74949.1 - 2.1e-09 37.8 0.1 2.3e-06 28.1 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ABK74949.1 - 2.9e-09 36.6 0.1 9.5e-05 21.8 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ABK74949.1 - 1.7e-07 30.7 0.7 1.7e-07 30.7 0.7 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 ABK74949.1 - 4.9e-07 29.5 2.1 1.3e-06 28.1 1.7 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ABK74949.1 - 3.5e-06 27.1 3.3 0.027 14.4 0.1 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 ABK74949.1 - 4.7e-05 22.8 1.5 7.6e-05 22.1 0.8 1.7 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 ABK74949.1 - 8.5e-05 21.8 0.2 0.0035 16.5 0.2 2.4 3 0 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.17 ABK74949.1 - 0.00012 21.4 0.1 0.0002 20.7 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 ABK74949.1 - 0.0005 19.4 0.0 0.0011 18.2 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ABK74949.1 - 0.016 14.3 1.0 0.14 11.1 0.3 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 ABK74949.1 - 0.043 13.1 0.1 0.089 12.1 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MCRA PF06100.11 ABK74949.1 - 0.048 12.5 0.0 0.076 11.8 0.0 1.3 1 0 0 1 1 1 0 MCRA family CclA_1 PF16942.5 ABK74949.1 - 0.09 13.1 1.3 18 5.7 0.0 2.6 2 0 0 2 2 2 0 Putative cyclic bacteriocin Trp_halogenase PF04820.14 ABK74949.1 - 0.095 11.5 1.0 0.9 8.3 0.6 2.1 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.18 ABK74949.1 - 0.18 11.7 0.1 0.34 10.8 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF900 PF05990.12 ABK74950.1 - 2.2e-06 27.3 0.0 2.4e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.20 ABK74950.1 - 0.0016 18.2 0.1 0.0064 16.2 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold FKBP_C PF00254.28 ABK74951.1 - 3.9e-12 46.3 0.0 5.6e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase AF-4 PF05110.13 ABK74951.1 - 7.1 4.6 5.4 7.7 4.5 5.4 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Urease_gamma PF00547.18 ABK74952.1 - 4.8e-48 161.5 0.1 5.3e-48 161.4 0.1 1.0 1 0 0 1 1 1 1 Urease, gamma subunit EamA PF00892.20 ABK74953.1 - 1.3e-17 64.2 34.5 4.6e-10 39.8 14.7 2.1 2 0 0 2 2 2 2 EamA-like transporter family Caa3_CtaG PF09678.10 ABK74954.1 - 6.8e-85 284.2 27.0 6.8e-85 284.2 27.0 2.9 2 1 0 2 2 2 1 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) CopD PF05425.13 ABK74954.1 - 1.3e-19 70.5 10.2 1.3e-19 70.5 10.2 6.2 3 2 3 7 7 7 2 Copper resistance protein D Sigma70_r3 PF04539.16 ABK74955.1 - 3e-26 91.3 2.6 1e-25 89.6 1.9 2.1 2 0 0 2 2 2 1 Sigma-70 region 3 Sigma70_r2 PF04542.14 ABK74955.1 - 3.2e-22 78.1 0.0 7.7e-22 76.8 0.0 1.7 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 ABK74955.1 - 1.4e-20 72.5 5.7 1.5e-19 69.3 1.3 2.8 3 0 0 3 3 3 2 Sigma-70, region 4 Sigma70_r1_2 PF00140.20 ABK74955.1 - 5.1e-13 48.8 0.1 1.4e-12 47.4 0.1 1.8 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 HTH_15 PF12324.8 ABK74955.1 - 0.00086 19.2 0.0 1.5 8.8 0.0 2.8 2 0 0 2 2 2 2 Helix-turn-helix domain of alkylmercury lyase KORA PF16509.5 ABK74955.1 - 0.11 12.8 0.0 2.4 8.5 0.0 2.5 2 0 0 2 2 2 0 TrfB plasmid transcriptional repressor TetR_N PF00440.23 ABK74956.1 - 5.8e-13 48.4 0.2 9.7e-13 47.7 0.2 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 ABK74956.1 - 0.016 15.5 0.1 0.028 14.7 0.1 1.5 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HTH_1 PF00126.27 ABK74957.1 - 5.1e-21 74.4 1.4 1e-20 73.4 1.4 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 ABK74957.1 - 2.1e-16 59.9 3.8 2.1e-16 59.9 3.8 2.0 2 0 0 2 2 2 1 LysR substrate binding domain AlaDh_PNT_C PF01262.21 ABK74959.1 - 2e-68 229.9 5.6 3.5e-68 229.1 5.6 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 ABK74959.1 - 1.4e-47 161.4 0.1 3.4e-47 160.1 0.1 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 ABK74959.1 - 3.7e-33 113.8 10.7 3.7e-33 113.8 10.7 2.5 3 0 0 3 3 3 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 ABK74959.1 - 0.0022 17.4 0.2 0.55 9.6 0.0 2.6 1 1 1 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DEDD_Tnp_IS110 PF01548.17 ABK74960.1 - 1.7e-25 89.7 0.5 3.8e-25 88.6 0.1 1.8 2 0 0 2 2 2 1 Transposase Transposase_20 PF02371.16 ABK74960.1 - 3.1e-08 33.8 2.5 5.7e-08 33.0 0.1 2.6 3 0 0 3 3 3 1 Transposase IS116/IS110/IS902 family AdoMet_MTase PF07757.13 ABK74960.1 - 0.17 12.3 0.0 0.43 10.9 0.0 1.6 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase ECH_1 PF00378.20 ABK74961.1 - 1.9e-49 168.3 0.0 3.4e-49 167.4 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK74961.1 - 1.8e-13 50.7 0.0 3.4e-13 49.8 0.0 1.4 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase UbiA PF01040.18 ABK74962.1 - 5e-16 58.8 22.0 5e-16 58.8 22.0 1.8 1 1 0 1 1 1 1 UbiA prenyltransferase family Cornichon PF03311.14 ABK74962.1 - 0.032 14.5 0.8 0.081 13.2 0.8 1.7 1 0 0 1 1 1 0 Cornichon protein SLC3A2_N PF16028.5 ABK74962.1 - 0.7 9.5 6.4 13 5.4 0.0 3.3 2 1 1 3 3 3 0 Solute carrier family 3 member 2 N-terminus T7SS_ESX_EspC PF10824.8 ABK74963.1 - 8.2e-05 23.0 9.9 0.00018 21.9 9.9 1.5 1 1 0 1 1 1 1 Excreted virulence factor EspC, type VII ESX diderm WXG100 PF06013.12 ABK74963.1 - 0.036 14.3 0.8 0.35 11.1 0.2 2.1 2 0 0 2 2 2 0 Proteins of 100 residues with WXG AAA_31 PF13614.6 ABK74964.1 - 1.3e-58 197.8 0.0 1.7e-58 197.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 ABK74964.1 - 3.6e-28 98.2 0.0 4.8e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 ABK74964.1 - 9.5e-11 41.6 0.0 3.8e-10 39.6 0.0 1.9 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase MipZ PF09140.11 ABK74964.1 - 9.5e-11 41.5 0.0 2.7e-09 36.7 0.0 2.2 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 ABK74964.1 - 3.9e-08 32.8 0.0 1e-07 31.5 0.0 1.8 1 1 0 1 1 1 1 Anion-transporting ATPase Fer4_NifH PF00142.18 ABK74964.1 - 5.5e-08 32.6 0.0 0.0001 21.9 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 ABK74964.1 - 1e-06 28.4 0.0 2.3e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ SRP54 PF00448.22 ABK74964.1 - 0.011 15.3 0.3 1.6 8.3 0.2 2.8 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 ABK74964.1 - 0.02 14.5 0.0 0.041 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain VirC1 PF07015.11 ABK74964.1 - 0.023 14.0 0.1 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 VirC1 protein YcaO PF02624.16 ABK74964.1 - 0.05 12.9 0.2 0.24 10.6 0.0 1.9 2 0 0 2 2 2 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding ATP_bind_1 PF03029.17 ABK74964.1 - 0.096 12.5 0.0 1.5 8.5 0.0 2.5 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 ABK74964.1 - 0.12 12.2 0.1 0.85 9.4 0.0 2.1 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Methyltransf_24 PF13578.6 ABK74964.1 - 0.12 13.4 0.0 0.67 11.0 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain MTHFR PF02219.17 ABK74965.1 - 0.24 10.7 0.0 0.7 9.2 0.0 1.7 2 0 0 2 2 2 0 Methylenetetrahydrofolate reductase DUF3551 PF12071.8 ABK74967.1 - 0.11 12.5 0.4 0.11 12.5 0.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3551) Pirin_C PF05726.13 ABK74968.1 - 1e-31 109.3 0.0 3.8e-31 107.5 0.0 1.9 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Pirin PF02678.16 ABK74968.1 - 9.5e-30 102.8 2.0 4.9e-29 100.5 0.7 2.4 3 0 0 3 3 3 1 Pirin Cupin_2 PF07883.11 ABK74968.1 - 2e-05 24.2 1.2 0.084 12.6 0.0 2.8 3 0 0 3 3 3 2 Cupin domain Cupin_1 PF00190.22 ABK74968.1 - 0.0019 17.8 0.0 0.0036 16.9 0.0 1.4 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 ABK74968.1 - 0.046 13.4 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF861) ECH_1 PF00378.20 ABK74969.1 - 3.1e-37 128.2 0.1 3.4e-37 128.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK74969.1 - 3.4e-20 72.8 0.0 4.1e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DLH PF01738.18 ABK74969.1 - 0.71 9.4 3.6 7.6 6.0 0.0 2.3 1 1 1 2 2 2 0 Dienelactone hydrolase family NUDIX PF00293.28 ABK74970.1 - 3.5e-05 23.9 0.0 5.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Rhodanese PF00581.20 ABK74971.1 - 2.2e-38 131.1 0.3 4.7e-19 68.9 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain RmlD_sub_bind PF04321.17 ABK74972.1 - 6.1e-101 337.3 0.3 7.7e-101 337.0 0.3 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 ABK74972.1 - 1.1e-26 93.9 0.3 1.9e-26 93.0 0.3 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ABK74972.1 - 8e-16 58.3 0.3 7.8e-14 51.8 0.0 2.3 1 1 1 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 ABK74972.1 - 7.3e-10 38.4 0.5 7.8e-09 35.1 0.0 2.1 1 1 1 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 ABK74972.1 - 1.1e-09 37.9 4.7 6.5e-08 32.1 1.0 2.9 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 ABK74972.1 - 3.4e-09 36.1 1.3 7.2e-09 35.0 0.0 1.8 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 ABK74972.1 - 0.00094 18.8 0.4 0.0013 18.4 0.4 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ABK74972.1 - 0.0012 18.8 7.0 0.099 12.5 7.0 2.3 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 ABK74972.1 - 0.0055 16.6 0.3 0.013 15.4 0.1 1.7 2 0 0 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 ABK74972.1 - 0.033 14.4 3.8 0.31 11.3 0.1 2.6 2 1 1 3 3 3 0 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 ABK74972.1 - 0.074 12.5 4.5 1 8.7 1.5 2.4 1 1 1 2 2 2 0 short chain dehydrogenase Aldedh PF00171.22 ABK74973.1 - 6.2e-28 97.5 10.1 7.9e-26 90.6 7.4 2.1 2 0 0 2 2 2 2 Aldehyde dehydrogenase family MoCF_biosynth PF00994.24 ABK74973.1 - 0.21 11.3 1.2 0.35 10.5 0.1 2.0 2 0 0 2 2 2 0 Probable molybdopterin binding domain NAD_binding_3 PF03447.16 ABK74973.1 - 2.7 8.7 8.6 1 10.0 1.5 3.0 2 1 0 3 3 3 0 Homoserine dehydrogenase, NAD binding domain Aldedh PF00171.22 ABK74974.1 - 6.4e-79 265.6 0.0 8.7e-79 265.2 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 ABK74974.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) p450 PF00067.22 ABK74975.1 - 5.2e-26 91.4 0.7 1.3e-23 83.6 0.8 2.2 1 1 0 1 1 1 1 Cytochrome P450 MspA PF09203.11 ABK74976.1 - 4.2e-40 137.4 0.1 5.4e-40 137.1 0.1 1.1 1 0 0 1 1 1 1 MspA YceI PF04264.13 ABK74977.1 - 2.1e-13 51.1 0.1 2.5e-13 50.8 0.1 1.1 1 0 0 1 1 1 1 YceI-like domain Atthog PF18800.1 ABK74978.1 - 0.046 13.6 0.0 0.061 13.2 0.0 1.1 1 0 0 1 1 1 0 Attenuator of Hedgehog Sigma70_r2 PF04542.14 ABK74979.1 - 1.6e-15 56.6 2.7 3.7e-15 55.4 2.7 1.6 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 ABK74979.1 - 3.8e-08 32.9 0.5 8.5e-08 31.8 0.0 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 ABK74979.1 - 1.4e-05 24.5 0.1 3e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 ABK74979.1 - 0.015 15.2 0.3 0.02 14.8 0.3 1.2 1 0 0 1 1 1 0 ECF sigma factor FMO-like PF00743.19 ABK74980.1 - 1.4e-19 69.9 0.0 2.3e-18 65.9 0.0 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ABK74980.1 - 3.5e-18 65.9 0.0 6.8e-17 61.7 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ABK74980.1 - 4.5e-13 49.2 0.0 3.6e-12 46.3 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 ABK74980.1 - 1.4e-11 44.2 0.1 2.5e-09 36.8 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 ABK74980.1 - 2.7e-08 33.4 0.0 6.2e-06 25.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ABK74980.1 - 5e-05 23.0 0.1 0.00029 20.5 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 ABK74980.1 - 0.00025 20.5 0.0 0.00039 19.8 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 ABK74980.1 - 0.00031 20.8 0.1 0.088 12.8 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 ABK74980.1 - 0.00039 19.6 0.0 0.00074 18.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 ABK74980.1 - 0.00058 20.4 0.0 0.008 16.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ABK74980.1 - 0.0021 17.4 0.0 0.0037 16.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ABK74980.1 - 0.016 14.0 0.0 0.15 10.7 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 ABK74980.1 - 0.11 11.6 0.1 5 6.1 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A ANTAR PF03861.14 ABK74982.1 - 1.8e-20 72.5 0.1 3.2e-20 71.7 0.1 1.4 1 0 0 1 1 1 1 ANTAR domain GAF_2 PF13185.6 ABK74982.1 - 8.4e-14 52.0 0.7 1.2e-13 51.5 0.7 1.2 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 ABK74982.1 - 0.0012 19.4 0.1 0.0022 18.6 0.1 1.3 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 ABK74982.1 - 0.033 14.6 0.1 0.053 13.9 0.1 1.4 1 0 0 1 1 1 0 GAF domain AA_permease_2 PF13520.6 ABK74985.1 - 8.8e-24 84.1 36.5 1.1e-23 83.8 36.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ABK74985.1 - 3.9e-18 65.3 29.1 8.2e-18 64.2 29.1 1.6 1 1 0 1 1 1 1 Amino acid permease Mce4_CUP1 PF11887.8 ABK74987.1 - 7.8e-58 195.9 0.0 1e-57 195.6 0.0 1.1 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative MlaD PF02470.20 ABK74987.1 - 1.1e-12 48.1 0.0 2.2e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 MlaD protein Trans_reg_C PF00486.28 ABK74988.1 - 2.5e-28 97.9 0.0 4.8e-28 97.0 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Methyltransf_25 PF13649.6 ABK74989.1 - 3.5e-17 62.9 0.1 5.9e-17 62.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABK74989.1 - 6e-16 58.9 0.0 9.4e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ABK74989.1 - 6.3e-12 45.3 0.0 9.4e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 ABK74989.1 - 1.7e-07 31.2 0.0 2.3e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK74989.1 - 2.9e-05 24.7 0.0 4.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABK74989.1 - 0.00011 22.1 0.0 0.00016 21.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 ABK74989.1 - 0.0009 18.9 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW UPF0020 PF01170.18 ABK74989.1 - 0.002 17.8 0.7 0.031 14.0 0.7 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Met_10 PF02475.16 ABK74989.1 - 0.02 14.6 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein TehB PF03848.14 ABK74989.1 - 0.049 13.0 0.0 0.07 12.5 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB PrmA PF06325.13 ABK74989.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.15 ABK74989.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase IclR PF01614.18 ABK74990.1 - 2.6e-17 62.8 0.3 4.5e-17 62.1 0.3 1.4 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 ABK74990.1 - 3.9e-10 39.4 0.4 3.6e-09 36.3 0.0 2.5 2 0 0 2 2 2 1 IclR helix-turn-helix domain MarR_2 PF12802.7 ABK74990.1 - 6e-06 26.0 1.1 3.5e-05 23.6 0.1 2.3 2 0 0 2 2 2 1 MarR family TrmB PF01978.19 ABK74990.1 - 0.00013 21.7 0.0 0.00036 20.4 0.0 1.7 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 ABK74990.1 - 0.0019 18.5 0.1 0.0073 16.6 0.0 1.9 2 0 0 2 2 2 1 Transcriptional regulator Fe_dep_repress PF01325.19 ABK74990.1 - 0.0078 16.4 0.0 0.021 15.0 0.0 1.7 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_5 PF01022.20 ABK74990.1 - 0.014 15.3 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 ABK74990.1 - 0.019 14.6 0.0 0.046 13.3 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR PF01047.22 ABK74990.1 - 0.023 14.6 0.1 0.06 13.3 0.0 1.7 2 0 0 2 2 2 0 MarR family DUF977 PF06163.11 ABK74990.1 - 0.028 14.4 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) RP-C PF03428.13 ABK74990.1 - 0.076 12.7 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Replication protein C N-terminal domain HTH_Crp_2 PF13545.6 ABK74990.1 - 0.12 12.3 0.4 0.33 10.9 0.0 2.0 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_36 PF13730.6 ABK74990.1 - 0.13 12.2 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain DUF1707 PF08044.11 ABK74992.1 - 9.6e-18 64.0 3.5 1e-17 63.9 1.7 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1707) DUF2154 PF09922.9 ABK74992.1 - 5.5e-05 23.0 0.1 0.00014 21.7 0.1 1.8 1 1 0 1 1 1 1 Cell wall-active antibiotics response 4TMS YvqF Bac_luciferase PF00296.20 ABK74993.1 - 1.3e-57 195.7 4.9 1.9e-57 195.0 4.9 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase DSS1_SEM1 PF05160.13 ABK74993.1 - 0.44 10.6 2.9 0.93 9.6 2.9 1.4 1 0 0 1 1 1 0 DSS1/SEM1 family NmrA PF05368.13 ABK74994.1 - 0.00027 20.6 0.1 0.00028 20.5 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ABK74994.1 - 0.00086 19.2 0.0 0.00093 19.1 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ABK74994.1 - 0.0029 17.1 0.1 0.0029 17.1 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 ABK74994.1 - 0.0039 17.1 0.1 0.0039 17.1 0.1 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ABK74994.1 - 0.0042 16.3 0.0 0.0045 16.2 0.0 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 ABK74994.1 - 0.0071 15.4 0.0 0.0074 15.3 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 ABK74994.1 - 0.018 14.5 0.1 0.018 14.5 0.1 1.1 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_4 PF07993.12 ABK74994.1 - 0.027 13.6 0.0 0.032 13.4 0.0 1.1 1 0 0 1 1 1 0 Male sterility protein DapB_N PF01113.20 ABK74994.1 - 0.062 13.4 0.1 0.062 13.4 0.1 1.2 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.17 ABK74994.1 - 0.16 11.0 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain MM_CoA_mutase PF01642.22 ABK74995.1 - 2.7e-231 768.6 0.1 3.2e-231 768.3 0.1 1.1 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 ABK74995.1 - 7.4e-15 55.1 1.1 1.5e-14 54.1 1.1 1.6 1 0 0 1 1 1 1 B12 binding domain Ca_hom_mod PF14798.6 ABK74995.1 - 0.21 10.6 0.1 0.35 9.9 0.1 1.2 1 0 0 1 1 1 0 Calcium homeostasis modulator S1 PF00575.23 ABK74996.1 - 5.5e-83 273.3 28.8 1.6e-26 92.4 1.7 4.1 4 0 0 4 4 4 4 S1 RNA binding domain DUF2110 PF09883.9 ABK74996.1 - 9.8e-07 28.6 1.2 0.15 11.7 0.1 3.3 3 0 0 3 3 3 2 Uncharacterized protein conserved in archaea (DUF2110) S1_2 PF13509.6 ABK74996.1 - 6e-06 26.2 6.2 0.025 14.6 0.1 4.9 4 2 0 4 4 4 2 S1 domain RNase_II_C_S1 PF18614.1 ABK74996.1 - 0.015 15.2 3.1 0.73 9.8 0.3 3.4 3 0 0 3 3 3 0 RNase II-type exonuclease C-terminal S1 domain CsrA PF02599.16 ABK74996.1 - 1.5 8.8 9.1 3.3 7.7 0.0 4.5 5 0 0 5 5 5 0 Global regulator protein family EFTUD2 PF16004.5 ABK74996.1 - 2.3 8.8 6.8 0.21 12.1 1.8 1.9 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Glycos_transf_1 PF00534.20 ABK74997.1 - 1.9e-22 79.6 0.0 4.8e-22 78.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ABK74997.1 - 1.3e-19 71.0 0.1 6.4e-18 65.5 0.1 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ABK74997.1 - 2.1e-17 63.6 0.7 6.9e-17 62.0 0.6 1.8 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 ABK74997.1 - 2e-10 41.4 1.7 2e-10 41.4 1.7 1.9 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 ABK74997.1 - 1.2e-06 28.8 0.1 3.6e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 ABK74997.1 - 0.023 14.8 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like HTH_31 PF13560.6 ABK74998.1 - 3.6e-13 49.6 0.1 6.4e-13 48.8 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 ABK74998.1 - 9.1e-12 44.9 0.0 1.4e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 ABK74998.1 - 2.1e-11 43.7 0.0 3.3e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Cupin_2 PF07883.11 ABK74998.1 - 1.4e-07 31.1 0.0 2.2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Cupin domain HTH_26 PF13443.6 ABK74998.1 - 7.9e-07 29.4 0.1 1.4e-06 28.6 0.1 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_37 PF13744.6 ABK74998.1 - 3.5e-06 26.9 0.1 5.1e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 ABK74998.1 - 0.0027 17.5 0.0 0.0046 16.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain AraC_binding PF02311.19 ABK74998.1 - 0.027 14.4 0.1 0.05 13.5 0.1 1.5 1 0 0 1 1 1 0 AraC-like ligand binding domain MarR PF01047.22 ABK74998.1 - 0.031 14.2 0.0 0.069 13.1 0.0 1.5 1 0 0 1 1 1 0 MarR family Cupin_7 PF12973.7 ABK74998.1 - 0.048 13.6 0.1 0.08 12.9 0.1 1.4 1 0 0 1 1 1 0 ChrR Cupin-like domain Cupin_3 PF05899.12 ABK74998.1 - 0.064 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DNA_binding_1 PF01035.20 ABK74999.1 - 6.6e-17 61.4 0.1 8e-17 61.1 0.1 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain HTH_28 PF13518.6 ABK74999.1 - 0.029 14.5 0.1 0.074 13.2 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain Cutinase PF01083.22 ABK75001.1 - 1.2e-44 152.4 0.0 1.5e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_6 PF12697.7 ABK75001.1 - 0.16 12.6 12.3 0.34 11.5 12.3 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 ABK75001.1 - 0.2 11.4 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DDE_Tnp_ISL3 PF01610.17 ABK75002.1 - 1.6e-64 217.9 0.0 2.1e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Transposase zf-ISL3 PF14690.6 ABK75002.1 - 1.1e-09 38.8 4.6 1.8e-09 38.1 2.5 2.5 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HTH_Tnp_ISL3 PF13542.6 ABK75002.1 - 2.4e-08 33.2 1.6 7e-08 31.8 1.6 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 ACPS PF01648.20 ABK75003.1 - 2.1e-19 69.7 0.0 2.5e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 ABK75003.1 - 0.14 12.3 5.0 1.9 8.6 0.2 2.5 2 1 0 2 2 2 0 4'-phosphopantetheinyl transferase N-terminal domain Sigma70_r4_2 PF08281.12 ABK75004.1 - 8.9e-15 54.1 0.0 1.6e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 ABK75004.1 - 3.1e-08 33.0 0.0 6.8e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 ABK75004.1 - 3.7e-08 33.0 0.3 9.6e-08 31.7 0.3 1.7 1 0 0 1 1 1 1 Sigma-70 region 2 SnoaL_2 PF12680.7 ABK75004.1 - 2.4e-07 31.3 3.5 1.1e-06 29.2 0.1 3.3 3 1 1 4 4 4 1 SnoaL-like domain DUF4440 PF14534.6 ABK75004.1 - 8.3e-05 22.9 0.0 0.0002 21.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 ABK75004.1 - 0.0037 17.5 0.0 0.0082 16.4 0.0 1.6 1 0 0 1 1 1 1 SnoaL-like domain Sigma70_ECF PF07638.11 ABK75004.1 - 0.031 14.2 0.3 0.054 13.4 0.3 1.4 1 0 0 1 1 1 0 ECF sigma factor MerR-DNA-bind PF09278.11 ABK75004.1 - 0.044 14.3 0.0 0.12 12.9 0.0 1.7 1 0 0 1 1 1 0 MerR, DNA binding DotD PF16816.5 ABK75004.1 - 0.067 13.2 0.1 0.22 11.5 0.1 1.8 2 0 0 2 2 2 0 DotD protein SnoaL PF07366.12 ABK75004.1 - 0.13 12.0 0.1 1 9.1 0.0 2.2 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase adh_short PF00106.25 ABK75005.1 - 1.1e-38 132.7 1.9 1.5e-38 132.3 1.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK75005.1 - 2.3e-32 112.4 6.5 3.1e-32 112.0 6.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK75005.1 - 4.5e-08 33.2 3.2 4.5e-08 33.2 3.2 1.5 2 0 0 2 2 2 1 KR domain 3HCDH_N PF02737.18 ABK75005.1 - 0.018 14.9 1.8 0.03 14.2 1.8 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 ABK75005.1 - 0.053 13.6 1.3 0.1 12.7 1.3 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Epimerase PF01370.21 ABK75005.1 - 0.091 12.2 1.0 0.18 11.2 0.9 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family CbiA PF01656.23 ABK75005.1 - 0.15 12.2 0.0 0.15 12.2 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 ABK75005.1 - 0.24 11.3 0.0 0.36 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain ADH_zinc_N PF00107.26 ABK75005.1 - 0.83 9.6 5.4 4.8 7.2 3.1 2.2 2 0 0 2 2 2 0 Zinc-binding dehydrogenase MerR_1 PF13411.6 ABK75006.1 - 5.8e-17 61.5 0.0 9.3e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 ABK75006.1 - 5.1e-13 48.6 0.1 8.1e-13 47.9 0.1 1.3 1 0 0 1 1 1 1 MerR family regulatory protein MerR-DNA-bind PF09278.11 ABK75006.1 - 3e-07 30.8 5.4 5.5e-06 26.8 5.4 2.3 1 1 0 1 1 1 1 MerR, DNA binding Rubella_E2 PF05749.11 ABK75006.1 - 0.022 14.2 0.0 0.027 14.0 0.0 1.0 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 WIYLD PF10440.9 ABK75006.1 - 0.12 12.2 0.1 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain Asp_Glu_race PF01177.22 ABK75008.1 - 1.7e-14 54.2 0.1 2.2e-14 53.8 0.1 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Amdase PF17645.1 ABK75008.1 - 0.008 15.8 2.9 0.016 14.8 1.9 1.9 1 1 1 2 2 2 1 Arylmalonate decarboxylase Shikimate_DH PF01488.20 ABK75008.1 - 0.1 12.7 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase WXG100 PF06013.12 ABK75010.1 - 0.0067 16.6 6.4 0.0067 16.6 6.4 3.8 1 1 2 3 3 3 1 Proteins of 100 residues with WXG Baculo_PEP_C PF04513.12 ABK75010.1 - 0.65 10.0 12.8 1 9.4 0.2 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PPE PF00823.19 ABK75010.1 - 1.1 9.3 23.2 0.059 13.5 16.8 2.1 1 1 1 2 2 2 0 PPE family DUF3584 PF12128.8 ABK75010.1 - 6.4 4.1 9.9 8.7 3.7 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) YlqD PF11068.8 ABK75010.1 - 6.9 7.1 12.1 16 5.9 3.7 2.4 2 0 0 2 2 2 0 YlqD protein DUF3060 PF11259.8 ABK75011.1 - 3.6e-21 74.6 4.2 3.6e-21 74.6 4.2 1.7 1 1 1 2 2 2 2 Protein of unknown function (DUF3060) LPD7 PF18821.1 ABK75011.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 7 TP_methylase PF00590.20 ABK75012.1 - 1.2e-48 165.9 6.0 2.2e-48 165.0 6.0 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 ABK75012.1 - 2.7e-22 79.1 0.1 1.1e-21 77.3 0.1 2.0 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 ABK75012.1 - 0.034 14.2 0.0 0.069 13.2 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Radical_SAM PF04055.21 ABK75012.1 - 0.049 14.0 0.1 0.34 11.3 0.0 2.4 2 1 0 2 2 2 0 Radical SAM superfamily 2-Hacid_dh_C PF02826.19 ABK75012.1 - 0.057 12.8 0.0 0.23 10.8 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 ABK75012.1 - 0.067 13.8 0.2 0.71 10.5 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_trans_4_4 PF13579.6 ABK75012.1 - 0.68 10.4 15.9 0.026 15.0 4.2 3.2 2 2 0 2 2 2 0 Glycosyl transferase 4-like domain PhzC-PhzF PF02567.16 ABK75013.1 - 7.7e-28 97.8 0.0 7.8e-19 68.2 0.0 2.0 1 1 1 2 2 2 2 Phenazine biosynthesis-like protein VWA_CoxE PF05762.14 ABK75014.1 - 1.3e-66 224.2 5.6 1.3e-66 224.2 5.6 1.5 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein VWA_2 PF13519.6 ABK75014.1 - 0.057 14.1 0.0 0.14 12.8 0.0 1.7 1 0 0 1 1 1 0 von Willebrand factor type A domain UDPGT PF00201.18 ABK75015.1 - 4.8e-14 52.0 0.0 4e-13 49.0 0.0 2.0 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 ABK75015.1 - 2.1e-05 24.6 0.0 3.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Peptidase_M24_C PF16188.5 ABK75015.1 - 0.028 14.5 0.0 0.059 13.4 0.0 1.5 1 1 0 1 1 1 0 C-terminal region of peptidase_M24 Arginase PF00491.21 ABK75016.1 - 1.4e-93 313.4 0.5 1.7e-93 313.2 0.5 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 ABK75016.1 - 0.024 14.9 0.1 0.038 14.2 0.1 1.3 1 0 0 1 1 1 0 UPF0489 domain DUF3373 PF11853.8 ABK75016.1 - 0.18 10.9 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) HTH_30 PF13556.6 ABK75017.1 - 1.3e-21 76.2 0.4 3e-21 75.0 0.4 1.7 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain GGDEF_2 PF17853.1 ABK75017.1 - 3.3e-12 46.7 1.6 3.3e-12 46.7 1.6 3.6 5 0 0 5 5 5 1 GGDEF-like domain DUF2089 PF09862.9 ABK75017.1 - 0.001 19.1 0.0 0.0024 17.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2089) HTH_8 PF02954.19 ABK75017.1 - 0.0052 16.5 0.1 0.016 15.0 0.1 1.8 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family DUF1989 PF09347.10 ABK75018.1 - 1.5e-51 174.4 0.0 1.9e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) DUF2118 PF09891.9 ABK75018.1 - 0.012 15.5 0.0 0.18 11.8 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) 4HBT PF03061.22 ABK75019.1 - 1.8e-06 28.2 0.2 3.3e-06 27.4 0.2 1.5 1 0 0 1 1 1 1 Thioesterase superfamily Flavin_Reduct PF01613.18 ABK75020.1 - 4e-28 98.4 0.1 4.6e-28 98.2 0.1 1.0 1 0 0 1 1 1 1 Flavin reductase like domain dUTPase PF00692.19 ABK75020.1 - 0.065 12.9 0.0 0.2 11.3 0.0 1.8 1 1 0 2 2 2 0 dUTPase PucR PF07905.11 ABK75021.1 - 6e-30 103.9 0.1 1.8e-29 102.4 0.1 1.8 1 0 0 1 1 1 1 Purine catabolism regulatory protein-like family HTH_30 PF13556.6 ABK75021.1 - 5.6e-17 61.3 4.0 1.2e-16 60.3 4.0 1.6 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_8 PF02954.19 ABK75021.1 - 0.0014 18.4 0.4 0.0051 16.6 0.4 2.0 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family sCache_3_2 PF17203.4 ABK75021.1 - 0.014 15.6 5.6 0.3 11.2 1.4 2.4 2 0 0 2 2 2 0 Single cache domain 3 DUF2089 PF09862.9 ABK75021.1 - 0.015 15.3 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) TLP1_add_C PF18313.1 ABK75021.1 - 1.3 9.1 4.4 2 8.4 0.2 3.2 3 1 1 4 4 4 0 Thiolase-like protein type 1 additional C-terminal domain DNA_ligase_A_M PF01068.21 ABK75022.1 - 3.7e-34 118.2 0.0 5e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 ABK75022.1 - 3.2e-14 53.3 0.0 5.4e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.19 ABK75022.1 - 0.16 11.8 0.0 2.9 7.7 0.0 2.2 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain PfkB PF00294.24 ABK75023.1 - 9e-50 169.7 10.1 1.3e-47 162.6 10.1 2.0 1 1 0 1 1 1 1 pfkB family carbohydrate kinase PGM_PMM_I PF02878.16 ABK75023.1 - 0.13 12.0 0.5 0.26 11.0 0.5 1.6 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Bac_luciferase PF00296.20 ABK75024.1 - 1.1e-78 264.8 0.9 1.3e-78 264.6 0.9 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase HSP20 PF00011.21 ABK75025.1 - 2.9e-17 62.7 0.1 3.4e-17 62.4 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ABK75025.1 - 5.8e-10 38.6 0.4 9.9e-10 37.8 0.4 1.4 1 1 0 1 1 1 1 HSP20-like domain found in ArsA PIH1_CS PF18201.1 ABK75025.1 - 0.0089 16.4 0.0 0.012 16.0 0.0 1.1 1 0 0 1 1 1 1 PIH1 CS-like domain SymE_toxin PF08845.10 ABK75025.1 - 0.12 12.4 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 Toxin SymE, type I toxin-antitoxin system Cutinase PF01083.22 ABK75026.1 - 1.2e-46 158.9 0.8 1.5e-46 158.6 0.8 1.1 1 0 0 1 1 1 1 Cutinase Ribonuc_L-PSP PF01042.21 ABK75027.1 - 7.3e-35 119.6 0.0 9.7e-17 61.1 0.0 3.1 2 1 0 2 2 2 2 Endoribonuclease L-PSP Abhydrolase_1 PF00561.20 ABK75028.1 - 3e-27 95.9 0.1 2.7e-26 92.8 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK75028.1 - 5.1e-13 50.1 8.9 6.1e-13 49.9 8.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK75028.1 - 7.6e-08 31.9 0.0 1.6e-06 27.6 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 EHN PF06441.12 ABK75028.1 - 0.014 15.8 0.1 0.027 14.8 0.1 1.5 1 0 0 1 1 1 0 Epoxide hydrolase N terminus FSH1 PF03959.13 ABK75028.1 - 0.092 12.4 0.0 0.49 10.0 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Ndr PF03096.14 ABK75028.1 - 0.23 10.1 0.0 0.32 9.7 0.0 1.2 1 0 0 1 1 1 0 Ndr family AMP-binding PF00501.28 ABK75029.1 - 2.3e-52 178.0 0.0 9.3e-52 176.0 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK75029.1 - 2.3e-13 50.9 1.1 6e-13 49.6 1.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Peptidase_S58 PF03576.14 ABK75030.1 - 2e-74 250.8 12.2 2.4e-74 250.5 12.2 1.0 1 0 0 1 1 1 1 Peptidase family S58 DUF72 PF01904.18 ABK75032.1 - 1.1e-60 205.5 0.0 1.2e-60 205.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF72 HATPase_c PF02518.26 ABK75033.1 - 1.4e-16 61.0 0.0 3.3e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ABK75033.1 - 5.2e-10 39.2 0.6 1.3e-09 37.9 0.6 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 ABK75033.1 - 6.3e-10 39.3 1.1 9.2e-09 35.5 0.2 2.6 2 0 0 2 2 2 1 HAMP domain HATPase_c_2 PF13581.6 ABK75033.1 - 5.1e-05 23.2 0.0 0.00011 22.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain LapA_dom PF06305.11 ABK75033.1 - 0.018 14.9 0.5 0.56 10.1 0.1 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain HATPase_c_3 PF13589.6 ABK75033.1 - 0.027 14.3 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TraL PF07178.11 ABK75033.1 - 0.035 14.6 0.0 2.4 8.7 0.0 2.3 2 0 0 2 2 2 0 TraL protein Herpes_gE PF02480.16 ABK75033.1 - 0.079 11.7 1.9 0.17 10.6 0.3 1.9 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E DUF4330 PF14221.6 ABK75033.1 - 0.43 10.8 2.3 37 4.5 0.1 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4330) Condensation PF00668.20 ABK75036.1 - 3.2e-105 352.5 0.0 9.6e-72 242.1 0.0 2.6 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.25 ABK75036.1 - 8.7e-11 42.0 0.0 2.5e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_3 PF07859.13 ABK75037.1 - 3e-66 223.3 0.5 4.9e-66 222.6 0.3 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ABK75037.1 - 1.9e-06 27.5 0.2 2.1e-05 24.1 0.2 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 ABK75037.1 - 2e-06 27.5 0.5 0.00011 21.8 0.3 2.2 2 0 0 2 2 2 1 Esterase PHB depolymerase COesterase PF00135.28 ABK75037.1 - 3.6e-05 22.8 0.3 7.6e-05 21.8 0.3 1.4 1 1 0 1 1 1 1 Carboxylesterase family AXE1 PF05448.12 ABK75037.1 - 6.2e-05 21.8 0.0 0.016 13.9 0.1 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.7 ABK75037.1 - 0.0012 17.8 0.0 0.0023 16.9 0.0 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme Say1_Mug180 PF10340.9 ABK75037.1 - 0.019 13.8 0.0 0.035 13.0 0.0 1.3 1 1 0 1 1 1 0 Steryl acetyl hydrolase Chlorophyllase PF07224.11 ABK75037.1 - 0.021 13.9 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase DLH PF01738.18 ABK75037.1 - 0.048 13.2 0.0 4.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family TetR_C_14 PF17754.1 ABK75039.1 - 2.4e-38 130.5 3.1 3.7e-38 129.9 3.1 1.3 1 0 0 1 1 1 1 MftR C-terminal domain TetR_N PF00440.23 ABK75039.1 - 5.2e-13 48.6 0.9 5.2e-13 48.6 0.9 2.2 3 0 0 3 3 3 1 Bacterial regulatory proteins, tetR family HTH_Tnp_1_2 PF13022.6 ABK75039.1 - 0.001 19.2 0.0 0.0031 17.6 0.0 1.8 2 1 0 2 2 2 1 Helix-turn-helix of insertion element transposase HTH_23 PF13384.6 ABK75039.1 - 0.0015 18.3 0.0 0.091 12.6 0.0 3.3 4 0 0 4 4 4 1 Homeodomain-like domain AbiEi_4 PF13338.6 ABK75039.1 - 0.0071 16.5 0.1 0.018 15.2 0.1 1.6 1 0 0 1 1 1 1 Transcriptional regulator, AbiEi antitoxin HTH_22 PF13309.6 ABK75039.1 - 0.02 15.0 0.0 1.4 9.0 0.0 2.6 2 0 0 2 2 2 0 HTH domain Glyco_hydro_114 PF03537.13 ABK75039.1 - 0.031 13.6 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 HTH_3 PF01381.22 ABK75039.1 - 0.052 13.6 0.0 1.4 9.0 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix HTH_7 PF02796.15 ABK75039.1 - 0.087 12.9 0.1 0.4 10.8 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase adh_short_C2 PF13561.6 ABK75040.1 - 3.1e-47 161.1 0.8 7.7e-47 159.8 0.8 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK75040.1 - 8.2e-43 146.1 1.0 1.1e-42 145.8 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK75040.1 - 1.1e-08 35.3 0.4 2.4e-08 34.1 0.3 1.6 1 1 0 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 ABK75040.1 - 0.00015 22.0 0.0 0.00025 21.3 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain THF_DHG_CYH_C PF02882.19 ABK75040.1 - 0.013 14.8 0.5 0.027 13.8 0.5 1.5 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 ABK75040.1 - 0.045 13.2 0.1 0.08 12.4 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 ABK75041.1 - 8.8e-13 48.8 0.0 1.2e-12 48.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABK75041.1 - 3.4e-11 43.1 0.0 4.1e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABK75041.1 - 2.8e-09 37.5 0.0 4.8e-09 36.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABK75041.1 - 4.5e-09 36.4 0.0 9.3e-09 35.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK75041.1 - 1.2e-08 35.6 0.0 2.8e-08 34.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 ABK75041.1 - 4.2e-07 29.9 0.0 1.1e-06 28.4 0.0 1.7 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 ABK75041.1 - 1.2e-05 24.9 0.0 6e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 ABK75041.1 - 2.1e-05 24.0 0.0 2.7e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.14 ABK75041.1 - 0.0014 18.1 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_15 PF09445.10 ABK75041.1 - 0.0071 15.9 0.0 0.0078 15.8 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.19 ABK75041.1 - 0.016 15.0 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 ABK75041.1 - 0.032 15.3 0.0 0.059 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 ABK75041.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Cu_amine_oxid PF01179.20 ABK75042.1 - 1.8e-152 508.1 0.0 2.1e-152 507.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 ABK75042.1 - 1.4e-17 64.0 0.0 3.5e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 ABK75042.1 - 3.8e-10 39.8 0.0 7e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain PIG-L PF02585.17 ABK75043.1 - 3.2e-26 92.5 0.1 5.2e-26 91.8 0.1 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Amidase PF01425.21 ABK75044.1 - 1.1e-92 311.4 0.0 1.3e-92 311.1 0.0 1.1 1 0 0 1 1 1 1 Amidase Pex14_N PF04695.13 ABK75045.1 - 0.028 15.1 2.3 0.028 15.1 2.3 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region YdjM PF04307.14 ABK75046.1 - 0.092 12.1 2.7 0.21 10.9 2.7 1.6 1 1 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase TMEM174 PF15029.6 ABK75046.1 - 0.2 11.3 0.2 0.26 11.0 0.2 1.1 1 0 0 1 1 1 0 Transmembrane protein 174 DUF2214 PF09980.9 ABK75046.1 - 0.24 11.2 7.0 0.11 12.3 3.2 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2214) Glutaredoxin PF00462.24 ABK75047.1 - 6.8e-16 58.2 0.0 8e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 ABK75047.1 - 0.002 18.5 0.0 0.0021 18.5 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N_3 PF13417.6 ABK75047.1 - 0.011 16.1 0.0 0.014 15.8 0.0 1.3 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ABK75047.1 - 0.013 15.8 0.0 0.017 15.4 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain SH3BGR PF04908.15 ABK75047.1 - 0.029 14.5 0.0 0.032 14.4 0.0 1.2 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein Thioredoxin_3 PF13192.6 ABK75047.1 - 0.087 12.9 0.1 0.13 12.4 0.1 1.3 1 1 0 1 1 1 0 Thioredoxin domain TetR_N PF00440.23 ABK75048.1 - 1.7e-12 46.9 0.1 3e-12 46.1 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family LysR_substrate PF03466.20 ABK75048.1 - 0.0002 20.8 0.4 0.15 11.4 0.0 2.2 2 0 0 2 2 2 2 LysR substrate binding domain HTH_IclR PF09339.10 ABK75048.1 - 0.0015 18.3 0.0 0.0033 17.2 0.0 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain TetR_C_15 PF17918.1 ABK75048.1 - 0.0028 18.4 0.7 0.0028 18.4 0.7 2.0 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_24 PF17932.1 ABK75048.1 - 0.0036 17.5 0.2 0.0075 16.5 0.2 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Rieske PF00355.26 ABK75049.1 - 4.3e-16 58.6 0.0 7.1e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Response_reg PF00072.24 ABK75050.1 - 1.1e-14 54.6 0.0 1.6e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 ABK75050.1 - 2.5e-12 46.2 0.0 4e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 ABK75050.1 - 0.0033 17.0 0.0 0.012 15.2 0.0 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 KORA PF16509.5 ABK75050.1 - 0.16 12.3 0.0 0.39 11.0 0.0 1.6 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor Peptidase_S9 PF00326.21 ABK75051.1 - 2.9e-47 160.9 0.1 4.5e-47 160.3 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 ABK75051.1 - 3.8e-15 56.2 0.3 1.2e-10 41.4 0.2 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 ABK75051.1 - 7.3e-11 42.0 0.0 3.5e-10 39.8 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 ABK75051.1 - 1.2e-09 37.8 0.3 2.9e-05 23.5 0.1 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ABK75051.1 - 1.4e-09 38.9 3.9 1.4e-09 38.9 3.9 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ABK75051.1 - 2e-08 34.2 0.5 9.9e-05 22.1 0.5 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 ABK75051.1 - 5.9e-06 26.3 1.1 3.8e-05 23.6 1.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 ABK75051.1 - 0.00019 21.2 0.0 0.0005 19.8 0.0 1.8 1 1 0 1 1 1 1 Putative esterase DUF2920 PF11144.8 ABK75051.1 - 0.00041 19.6 0.2 0.00064 19.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Esterase_phd PF10503.9 ABK75051.1 - 0.00054 19.5 1.4 0.0022 17.5 1.4 1.9 1 1 0 1 1 1 1 Esterase PHB depolymerase BAAT_C PF08840.11 ABK75051.1 - 0.0029 17.6 0.0 0.0076 16.2 0.0 1.6 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DPPIV_N PF00930.21 ABK75051.1 - 0.0069 15.2 0.0 0.015 14.1 0.0 1.5 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region WW PF00397.26 ABK75051.1 - 0.0074 16.4 2.4 0.013 15.6 0.2 2.4 2 0 0 2 2 2 1 WW domain AXE1 PF05448.12 ABK75051.1 - 0.036 12.7 0.7 0.26 9.9 0.7 1.9 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) FSH1 PF03959.13 ABK75051.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Amidinotransf PF02274.17 ABK75051.1 - 0.16 11.0 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Amidinotransferase PD40 PF07676.12 ABK75051.1 - 0.6 10.1 3.9 3.8 7.6 0.0 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat CN_hydrolase PF00795.22 ABK75052.1 - 1.1e-41 143.0 0.0 1.2e-41 142.8 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase ETF PF01012.21 ABK75052.1 - 0.016 15.1 0.6 0.4 10.6 1.1 2.3 2 1 0 2 2 2 0 Electron transfer flavoprotein domain Bac_luciferase PF00296.20 ABK75053.1 - 1.1e-73 248.5 2.0 1.2e-73 248.3 2.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Alkyl_sulf_dimr PF14863.6 ABK75054.1 - 3.7e-57 192.7 0.0 6.6e-57 191.9 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.27 ABK75054.1 - 4.5e-42 144.3 5.5 1.1e-41 143.1 5.5 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Alkyl_sulf_C PF14864.6 ABK75054.1 - 3.5e-33 114.5 0.0 5.8e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B_2 PF12706.7 ABK75054.1 - 5.9e-07 29.2 0.3 1.7e-06 27.7 0.3 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain 2OG-FeII_Oxy_3 PF13640.6 ABK75054.1 - 0.017 16.0 0.1 0.04 14.8 0.1 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily ANAPC3 PF12895.7 ABK75054.1 - 0.029 14.6 0.0 0.47 10.7 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 ABC2_membrane_2 PF12679.7 ABK75055.1 - 9.1e-06 25.1 16.9 1.2e-05 24.8 16.9 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 ABK75055.1 - 2.4e-05 24.4 4.5 2.4e-05 24.4 4.5 2.2 2 1 0 2 2 2 1 ABC-2 family transporter protein ESX-1_EspG PF14011.6 ABK75056.1 - 9.6e-53 179.3 5.2 1.1e-52 179.1 5.2 1.0 1 0 0 1 1 1 1 EspG family Peptidase_S15 PF02129.18 ABK75057.1 - 2.3e-49 168.4 1.8 3e-49 168.0 1.8 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 ABK75057.1 - 9.3e-35 120.6 1.8 1.3e-34 120.1 0.5 1.8 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 ABK75057.1 - 0.04 13.2 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 4HBT_3 PF13622.6 ABK75058.1 - 3.3e-38 132.4 1.3 3.9e-38 132.1 1.3 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 ABK75058.1 - 3e-21 75.7 0.0 3.8e-20 72.1 0.0 2.3 2 1 1 3 3 3 1 Acyl-CoA thioesterase HAD_2 PF13419.6 ABK75059.1 - 5.9e-14 52.5 0.0 8.4e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ABK75059.1 - 7.4e-10 39.5 0.2 3.9e-08 33.8 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ABK75059.1 - 0.061 13.4 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 HAD-hyrolase-like TetR_N PF00440.23 ABK75060.1 - 2.2e-13 49.7 3.8 2.8e-13 49.4 1.1 2.2 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_14 PF17754.1 ABK75060.1 - 4.9e-05 23.3 2.1 9.6e-05 22.3 2.1 1.5 1 0 0 1 1 1 1 MftR C-terminal domain HTH_Tnp_1_2 PF13022.6 ABK75060.1 - 0.0029 17.8 0.1 0.11 12.6 0.0 2.3 2 1 0 2 2 2 1 Helix-turn-helix of insertion element transposase LytR_C PF13399.6 ABK75060.1 - 0.0081 17.1 1.6 0.028 15.4 0.4 2.1 2 0 0 2 2 2 1 LytR cell envelope-related transcriptional attenuator DUF2934 PF11154.8 ABK75060.1 - 0.081 12.6 4.8 0.16 11.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2934) MMPL PF03176.15 ABK75061.1 - 9.6e-99 330.4 41.9 4.6e-53 180.3 13.9 2.8 2 2 0 2 2 2 2 MMPL family Sterol-sensing PF12349.8 ABK75061.1 - 0.00014 21.7 9.6 0.087 12.7 0.1 2.7 2 1 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation YchF-GTPase_C PF06071.13 ABK75062.1 - 3.2e-38 129.8 0.1 7.3e-38 128.6 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 ABK75062.1 - 5.2e-23 81.3 0.0 1.7e-22 79.7 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ABK75062.1 - 3.9e-08 33.0 0.0 8e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 ABK75062.1 - 0.016 15.2 1.3 0.087 12.9 0.4 2.6 2 1 0 2 2 2 0 TGS domain Dynamin_N PF00350.23 ABK75062.1 - 0.028 14.5 0.0 0.73 9.9 0.0 2.6 3 0 0 3 3 3 0 Dynamin family AAA_18 PF13238.6 ABK75062.1 - 0.92 10.1 2.8 0.92 10.1 0.0 2.5 3 0 0 3 3 3 0 AAA domain PCuAC PF04314.13 ABK75063.1 - 4.1e-36 123.1 0.2 5.5e-36 122.7 0.2 1.2 1 0 0 1 1 1 1 Copper chaperone PCu(A)C LPAM_1 PF08139.12 ABK75063.1 - 0.041 14.4 0.9 0.07 13.7 0.9 1.4 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site DUF11 PF01345.18 ABK75063.1 - 0.059 13.7 0.2 4.3 7.7 0.2 2.3 1 1 0 1 1 1 0 Domain of unknown function DUF11 Aminotran_5 PF00266.19 ABK75064.1 - 2e-14 53.4 0.0 2e-11 43.5 0.0 2.2 1 1 0 2 2 2 2 Aminotransferase class-V Glyco_hydro_30C PF17189.4 ABK75064.1 - 0.093 13.0 0.1 1.2 9.4 0.1 2.3 2 0 0 2 2 2 0 Glycosyl hydrolase family 30 beta sandwich domain CN_hydrolase PF00795.22 ABK75065.1 - 6.9e-45 153.4 0.1 7.9e-45 153.2 0.1 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Med9 PF07544.13 ABK75066.1 - 0.0049 16.9 0.8 0.0067 16.5 0.8 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 DinB_2 PF12867.7 ABK75066.1 - 0.044 14.3 1.0 0.053 14.0 1.0 1.2 1 0 0 1 1 1 0 DinB superfamily ABC_membrane PF00664.23 ABK75067.1 - 5.6e-32 111.5 0.0 7.7e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 ABK75067.1 - 1.3e-22 80.7 0.0 2.6e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 ABK75067.1 - 0.022 14.5 0.2 0.071 12.9 0.2 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 ABK75067.1 - 0.023 15.0 0.3 0.13 12.5 0.3 2.2 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ABK75067.1 - 0.027 15.0 0.0 0.056 14.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ABK75067.1 - 0.042 13.4 8.0 0.44 10.1 8.0 2.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 ABK75067.1 - 0.057 13.9 0.2 0.36 11.2 0.2 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 ABK75067.1 - 0.069 12.9 0.6 0.31 10.8 0.6 2.0 1 1 0 1 1 1 0 DEAD/DEAH box helicase Mg_chelatase PF01078.21 ABK75067.1 - 0.095 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF87 PF01935.17 ABK75067.1 - 0.36 10.9 0.9 0.6 10.2 0.9 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain SKI PF01202.22 ABK75068.1 - 5.4e-13 49.4 0.0 6.3e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 ABK75068.1 - 0.00012 22.6 0.0 0.00018 22.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ABK75068.1 - 0.0011 19.1 0.0 0.0045 17.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 ABK75068.1 - 0.0022 18.2 0.0 0.0022 18.2 0.0 1.3 1 1 0 1 1 1 1 Cytidylate kinase-like family Cytidylate_kin PF02224.18 ABK75068.1 - 0.0048 16.7 0.1 0.013 15.3 0.0 1.7 2 0 0 2 2 2 1 Cytidylate kinase AAA_22 PF13401.6 ABK75068.1 - 0.0092 16.3 0.0 0.017 15.4 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ABK75068.1 - 0.027 14.9 0.1 0.034 14.5 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain APS_kinase PF01583.20 ABK75068.1 - 0.089 12.7 0.0 0.12 12.3 0.0 1.4 1 1 0 1 1 1 0 Adenylylsulphate kinase AAA_17 PF13207.6 ABK75068.1 - 0.1 13.0 0.0 0.24 11.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 ABK75068.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CoaE PF01121.20 ABK75068.1 - 0.12 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_28 PF13521.6 ABK75068.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ABK75068.1 - 0.13 12.8 0.0 0.2 12.2 0.0 1.3 1 0 0 1 1 1 0 ABC transporter PRK PF00485.18 ABK75068.1 - 0.14 11.8 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family CbiA PF01656.23 ABK75068.1 - 0.16 12.0 0.0 0.16 12.0 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain dNK PF01712.19 ABK75068.1 - 0.19 11.5 0.0 0.4 10.5 0.0 1.5 2 0 0 2 2 2 0 Deoxynucleoside kinase PucR PF07905.11 ABK75069.1 - 3.4e-24 85.4 0.0 7.4e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 Purine catabolism regulatory protein-like family HTH_30 PF13556.6 ABK75069.1 - 1e-17 63.7 4.3 1.6e-17 63.1 2.1 2.4 3 0 0 3 3 3 1 PucR C-terminal helix-turn-helix domain DUF1876 PF08962.11 ABK75069.1 - 0.011 15.7 2.4 0.021 14.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1876) DUF2089 PF09862.9 ABK75069.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) HTH_Tnp_ISL3 PF13542.6 ABK75069.1 - 1.3 8.5 3.9 2 7.9 0.4 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 Pyr_redox_2 PF07992.14 ABK75070.1 - 1.2e-46 159.3 1.0 1.5e-46 159.0 1.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ABK75070.1 - 4.5e-28 97.7 0.1 8.9e-28 96.8 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 ABK75070.1 - 5.7e-13 49.2 0.1 1.5e-12 47.9 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ABK75070.1 - 1.2e-11 44.4 0.0 1.8e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ABK75070.1 - 0.00059 19.1 0.1 0.0034 16.6 0.0 2.1 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 ABK75070.1 - 0.00091 19.2 2.2 1 9.3 0.1 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding HI0933_like PF03486.14 ABK75070.1 - 0.0013 17.6 0.0 0.84 8.3 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein Lycopene_cycl PF05834.12 ABK75070.1 - 0.069 12.2 0.2 0.86 8.6 0.1 2.2 1 1 1 2 2 2 0 Lycopene cyclase protein Amino_oxidase PF01593.24 ABK75070.1 - 0.1 11.9 0.3 4.9 6.3 0.0 2.5 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.18 ABK75070.1 - 0.16 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 ABK75070.1 - 0.85 9.1 10.4 34 3.9 2.1 3.9 2 1 2 4 4 4 0 FAD dependent oxidoreductase AAA_30 PF13604.6 ABK75071.1 - 1.2e-41 142.5 4.8 1.2e-41 142.5 4.8 2.6 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.6 ABK75071.1 - 5.9e-30 104.5 1.4 2.2e-29 102.7 0.3 2.2 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 ABK75071.1 - 3.9e-15 55.4 0.2 1.2e-14 53.8 0.2 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_11 PF13086.6 ABK75071.1 - 4.9e-12 46.2 0.1 1.4e-06 28.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain Helicase_RecD PF05127.14 ABK75071.1 - 1.6e-11 44.3 0.2 3.6e-11 43.2 0.0 1.6 2 0 0 2 2 2 1 Helicase Viral_helicase1 PF01443.18 ABK75071.1 - 4.9e-11 42.8 2.7 7.7e-06 25.8 0.2 3.1 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 ABK75071.1 - 2.8e-09 37.4 0.2 8.4e-09 35.8 0.1 1.9 2 0 0 2 2 1 1 AAA domain UvrD-helicase PF00580.21 ABK75071.1 - 1.7e-05 24.5 0.9 0.0015 18.2 0.5 2.2 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain SH3_13 PF18335.1 ABK75071.1 - 1.8e-05 24.4 0.0 3.7e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain AAA_16 PF13191.6 ABK75071.1 - 0.00053 20.4 3.4 0.0016 18.9 3.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 ABK75071.1 - 0.0013 19.0 0.3 0.0044 17.3 0.0 2.1 2 0 0 2 2 1 1 AAA domain PhoH PF02562.16 ABK75071.1 - 0.002 17.6 1.8 0.053 13.0 1.8 2.3 1 1 0 1 1 1 1 PhoH-like protein NTPase_1 PF03266.15 ABK75071.1 - 0.01 15.7 0.1 0.038 13.9 0.1 1.8 2 0 0 2 2 2 0 NTPase AAA_33 PF13671.6 ABK75071.1 - 0.015 15.5 0.5 0.065 13.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 ABK75071.1 - 0.015 14.4 0.0 0.04 13.0 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 ABK75071.1 - 0.015 14.7 0.4 0.034 13.5 0.4 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI UvrD_C PF13361.6 ABK75071.1 - 0.027 13.9 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 ABK75071.1 - 0.044 11.7 0.2 0.54 8.1 0.1 2.1 2 0 0 2 2 2 0 Helicase CbiA PF01656.23 ABK75071.1 - 0.066 13.3 0.4 0.15 12.1 0.4 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.22 ABK75071.1 - 0.084 12.5 0.2 0.15 11.6 0.2 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_29 PF13555.6 ABK75071.1 - 0.09 12.5 0.1 0.23 11.2 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 ABK75071.1 - 0.097 12.7 1.6 0.2 11.7 0.2 2.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 ABK75071.1 - 0.099 13.1 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 ABK75071.1 - 0.11 11.3 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.6 ABK75071.1 - 0.15 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 ABK75071.1 - 0.2 10.9 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 ABK75071.1 - 0.31 11.5 1.1 0.76 10.2 1.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Peripla_BP_1 PF00532.21 ABK75072.1 - 5.8e-31 108.0 0.0 7.3e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 ABK75072.1 - 3.2e-28 99.1 0.9 4.7e-27 95.4 0.3 2.2 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_4 PF13407.6 ABK75072.1 - 2e-25 89.9 0.0 5.3e-25 88.5 0.0 1.7 1 1 0 1 1 1 1 Periplasmic binding protein domain LacI PF00356.21 ABK75072.1 - 2.8e-13 49.4 1.2 7.1e-13 48.1 1.2 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family HTH_31 PF13560.6 ABK75072.1 - 2.7e-06 27.6 3.1 2.7e-06 27.6 3.1 2.3 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_3 PF01381.22 ABK75072.1 - 0.00022 21.2 0.0 0.00049 20.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix PucR PF07905.11 ABK75072.1 - 0.005 17.1 0.0 0.018 15.3 0.0 1.9 1 1 1 2 2 2 1 Purine catabolism regulatory protein-like family HTH_AsnC-type PF13404.6 ABK75072.1 - 0.009 15.8 0.3 0.009 15.8 0.3 3.4 3 0 0 3 3 3 1 AsnC-type helix-turn-helix domain YdaS_antitoxin PF15943.5 ABK75072.1 - 0.0092 15.8 0.0 0.024 14.5 0.0 1.7 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT MarR_2 PF12802.7 ABK75072.1 - 0.017 15.0 4.4 0.14 12.1 0.1 3.1 3 0 0 3 3 3 0 MarR family HTH_10 PF04967.12 ABK75072.1 - 0.017 14.9 0.2 0.88 9.4 0.0 2.7 2 0 0 2 2 2 0 HTH DNA binding domain HTH_23 PF13384.6 ABK75072.1 - 0.021 14.6 1.1 0.53 10.2 0.0 3.0 1 1 1 2 2 2 0 Homeodomain-like domain Put_DNA-bind_N PF06971.13 ABK75072.1 - 0.021 14.8 0.2 9.2 6.4 0.1 2.7 2 0 0 2 2 2 0 Putative DNA-binding protein N-terminus HTH_24 PF13412.6 ABK75072.1 - 0.035 13.7 1.0 0.093 12.3 0.0 2.3 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_38 PF13936.6 ABK75072.1 - 0.066 13.0 0.3 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain Peptidase_S9 PF00326.21 ABK75073.1 - 5.5e-07 29.3 0.6 4.4e-06 26.3 0.0 2.2 2 1 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 ABK75073.1 - 3e-05 23.4 0.2 0.00029 20.2 0.2 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 LIP PF03583.14 ABK75073.1 - 7.5e-05 22.2 0.9 0.00011 21.6 0.9 1.2 1 0 0 1 1 1 1 Secretory lipase DLH PF01738.18 ABK75073.1 - 0.00022 20.8 0.0 0.0004 20.0 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family HDPD PF02924.14 ABK75073.1 - 0.092 12.9 0.2 0.19 11.8 0.2 1.5 1 0 0 1 1 1 0 Bacteriophage lambda head decoration protein D Abhydrolase_2 PF02230.16 ABK75073.1 - 0.22 11.3 0.0 0.77 9.5 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Cytochrome_CBB3 PF13442.6 ABK75074.1 - 5.2e-23 81.1 0.0 6.9e-13 48.7 0.0 2.5 2 0 0 2 2 2 2 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 ABK75074.1 - 2.4e-16 60.6 2.8 2.5e-06 28.5 0.1 4.0 2 2 0 2 2 2 2 Cytochrome c Cytochrom_C550 PF14495.6 ABK75074.1 - 2.9e-05 23.8 0.1 0.32 10.7 0.0 2.8 2 1 1 3 3 3 2 Cytochrome c-550 domain DUF1924 PF09086.11 ABK75074.1 - 0.0026 18.1 0.5 2.5 8.5 0.0 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF1924) CCP_MauG PF03150.14 ABK75074.1 - 0.0084 16.8 0.0 4.7 7.8 0.0 2.2 2 0 0 2 2 2 2 Di-haem cytochrome c peroxidase Cytochrome_C7 PF14522.6 ABK75074.1 - 0.031 14.3 0.0 9.3 6.3 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c Paired_CXXCH_1 PF09699.10 ABK75074.1 - 0.065 13.0 0.2 12 5.7 0.0 2.4 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrom_C1 PF02167.15 ABK75074.1 - 0.11 12.2 0.1 5.6 6.6 0.0 2.3 2 0 0 2 2 2 0 Cytochrome C1 family p450 PF00067.22 ABK75075.1 - 6.2e-22 78.0 0.0 7.1e-16 58.0 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 FmdA_AmdA PF03069.15 ABK75076.1 - 6.8e-29 100.9 0.1 4e-17 62.1 0.1 2.5 1 1 1 2 2 2 2 Acetamidase/Formamidase family Bac_luciferase PF00296.20 ABK75077.1 - 3.4e-67 227.1 3.1 4e-67 226.9 3.1 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF1028 PF06267.12 ABK75078.1 - 2e-59 200.6 0.5 2.3e-59 200.4 0.5 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF1028) DUF3040 PF11239.8 ABK75080.1 - 2.3e-29 101.5 0.7 3.7e-29 100.8 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3040) Phage_holin_3_6 PF07332.11 ABK75080.1 - 0.006 16.6 1.4 0.0087 16.1 1.4 1.1 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III Ni_hydr_CYTB PF01292.20 ABK75080.1 - 0.018 14.6 0.1 0.021 14.4 0.1 1.3 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 DUF2207 PF09972.9 ABK75080.1 - 0.09 11.5 0.0 0.098 11.4 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3185 PF11381.8 ABK75080.1 - 0.34 11.0 8.3 2.9 8.0 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3185) PRA-CH PF01502.18 ABK75081.1 - 4.6e-33 112.9 0.5 6.8e-33 112.3 0.5 1.3 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase MR_MLE_C PF13378.6 ABK75082.1 - 2.5e-40 138.4 0.9 2.5e-40 138.4 0.9 1.5 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 ABK75082.1 - 1e-05 25.7 0.1 2.1e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Radical_SAM PF04055.21 ABK75082.1 - 0.1 13.0 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 Radical SAM superfamily Ribosomal_L5_C PF00673.21 ABK75083.1 - 5.8e-39 132.2 0.0 1.1e-38 131.2 0.0 1.5 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 ABK75083.1 - 8.2e-26 90.1 0.6 1.3e-25 89.5 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L5 Radical_SAM PF04055.21 ABK75084.1 - 1.4e-13 51.5 0.0 2.5e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily LIAS_N PF16881.5 ABK75084.1 - 4.2e-08 33.6 0.2 7.8e-08 32.7 0.2 1.4 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family DUF21 PF01595.20 ABK75085.1 - 1.6e-32 112.6 2.9 2.1e-32 112.2 2.9 1.1 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 ABK75085.1 - 2.2e-14 53.2 1.3 3.2e-14 52.7 0.2 1.9 2 0 0 2 2 2 1 Transporter associated domain CBS PF00571.28 ABK75085.1 - 2.4e-13 50.3 2.4 4.1e-06 27.1 0.1 3.2 3 0 0 3 3 3 2 CBS domain Usp PF00582.26 ABK75086.1 - 7.5e-26 91.3 2.6 9.4e-26 91.0 2.6 1.1 1 0 0 1 1 1 1 Universal stress protein family DUF5539 PF17693.1 ABK75086.1 - 0.11 12.2 0.4 0.15 11.7 0.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5539) TetR_N PF00440.23 ABK75087.1 - 4.4e-13 48.8 0.3 1.2e-12 47.4 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 ABK75087.1 - 1.4e-09 38.3 7.8 2.8e-09 37.3 7.8 1.5 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain HTH_23 PF13384.6 ABK75087.1 - 0.00023 20.9 0.2 0.00069 19.3 0.1 1.9 2 0 0 2 2 2 1 Homeodomain-like domain TetR_C_16 PF17920.1 ABK75087.1 - 0.00023 21.3 3.0 0.00043 20.5 3.0 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain HTH_Tnp_1_2 PF13022.6 ABK75087.1 - 0.0012 19.0 0.0 0.0019 18.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix of insertion element transposase HTH_3 PF01381.22 ABK75087.1 - 0.0037 17.3 0.0 0.0092 16.0 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_7 PF02796.15 ABK75087.1 - 0.0049 16.9 0.0 0.0099 15.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 ABK75087.1 - 0.0055 16.8 0.7 0.019 15.1 0.0 2.3 3 0 0 3 3 3 1 Helix-turn-helix domain Sigma70_ECF PF07638.11 ABK75087.1 - 0.019 14.9 0.3 0.05 13.5 0.0 1.8 2 0 0 2 2 2 0 ECF sigma factor TetR_C_24 PF17932.1 ABK75087.1 - 0.06 13.6 0.7 0.11 12.7 0.7 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HTH_31 PF13560.6 ABK75087.1 - 0.078 13.3 0.2 0.078 13.3 0.2 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.7 ABK75087.1 - 0.091 13.0 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Hydrolase_4 PF12146.8 ABK75088.1 - 4.8e-24 84.9 0.1 7.9e-24 84.2 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ABK75088.1 - 5.4e-22 79.5 8.1 6.9e-22 79.1 8.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ABK75088.1 - 1.2e-20 74.3 0.0 2.4e-19 70.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 ABK75088.1 - 1.1e-06 28.7 0.1 0.0024 17.8 0.0 2.8 3 0 0 3 3 3 2 Serine hydrolase Abhydrolase_4 PF08386.10 ABK75088.1 - 8.3e-06 25.9 0.0 4.3e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 TAP-like protein Thioesterase PF00975.20 ABK75088.1 - 1.4e-05 25.4 0.0 3.4e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 Thioesterase domain DUF900 PF05990.12 ABK75088.1 - 0.00032 20.3 0.0 0.00048 19.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Esterase PF00756.20 ABK75088.1 - 0.00039 20.1 0.0 0.00052 19.7 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 ABK75088.1 - 0.0033 17.3 1.1 0.05 13.4 1.1 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ABK75088.1 - 0.0046 16.4 0.0 0.47 9.9 0.0 2.8 2 1 1 3 3 3 1 Prolyl oligopeptidase family LIDHydrolase PF10230.9 ABK75088.1 - 0.025 14.2 0.0 0.07 12.7 0.0 1.7 1 1 0 1 1 1 0 Lipid-droplet associated hydrolase PGAP1 PF07819.13 ABK75088.1 - 0.073 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein LCAT PF02450.15 ABK75088.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase FSH1 PF03959.13 ABK75088.1 - 0.21 11.2 0.0 5.4 6.6 0.0 2.4 1 1 1 2 2 2 0 Serine hydrolase (FSH1) ApbA_C PF08546.11 ABK75090.1 - 2.1e-29 102.2 0.0 4.9e-29 101.1 0.1 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 ABK75090.1 - 2.2e-24 85.8 0.0 9.5e-24 83.8 0.0 1.9 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 ABK75090.1 - 0.0003 21.3 0.4 0.0007 20.1 0.4 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 ABK75090.1 - 0.0062 16.4 4.1 0.0083 16.0 0.5 2.5 2 1 1 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 ABK75090.1 - 0.0071 15.6 0.4 0.0071 15.6 0.4 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GFO_IDH_MocA PF01408.22 ABK75090.1 - 0.14 13.0 0.1 0.6 10.9 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold UDPG_MGDP_dh_N PF03721.14 ABK75090.1 - 0.17 11.5 0.1 0.31 10.6 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Acetyltransf_10 PF13673.7 ABK75091.1 - 2.3e-14 53.5 0.0 2.7e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ABK75091.1 - 8.9e-07 29.2 0.0 1.2e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ABK75091.1 - 0.0015 18.6 0.0 0.003 17.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ABK75091.1 - 0.0018 18.5 0.0 0.0023 18.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family NS3 PF17530.2 ABK75091.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Non-structural protein NS3 OKR_DC_1 PF01276.20 ABK75092.1 - 2.9e-49 167.9 0.0 1.2e-47 162.6 0.0 2.0 1 1 1 2 2 2 2 Orn/Lys/Arg decarboxylase, major domain OKR_DC_1_C PF03711.15 ABK75092.1 - 4.2e-14 53.0 0.2 7.3e-14 52.2 0.2 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, C-terminal domain Cys_Met_Meta_PP PF01053.20 ABK75092.1 - 0.0059 15.2 0.0 0.0098 14.5 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SepSecS PF05889.13 ABK75092.1 - 0.037 12.7 0.0 0.054 12.2 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Amdase PF17645.1 ABK75093.1 - 4.8e-21 75.4 0.4 6.6e-21 74.9 0.4 1.2 1 0 0 1 1 1 1 Arylmalonate decarboxylase Asp_Glu_race PF01177.22 ABK75093.1 - 1.4e-05 25.1 0.3 0.00011 22.1 0.3 2.3 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase CMAS PF02353.20 ABK75094.1 - 1.6e-119 398.2 0.0 1.9e-119 398.0 0.0 1.0 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 ABK75094.1 - 7.1e-10 39.0 0.0 1.1e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK75094.1 - 2e-08 34.9 0.0 3.5e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABK75094.1 - 3.5e-08 34.1 0.0 7.4e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABK75094.1 - 4.4e-06 27.2 0.0 1.3e-05 25.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABK75094.1 - 0.0066 16.3 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ABK75094.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pilus_CpaD PF09476.10 ABK75094.1 - 0.14 11.9 0.1 1.8 8.2 0.0 2.1 2 0 0 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) DUF1059 PF06348.11 ABK75095.1 - 0.00025 21.2 0.2 0.00029 21.0 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1059) CsbD PF05532.12 ABK75096.1 - 4.1e-09 36.2 3.8 4.1e-09 36.2 3.8 2.9 2 1 1 3 3 3 1 CsbD-like DUF4778 PF16008.5 ABK75096.1 - 0.51 10.3 13.1 0.64 10.0 13.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) TetR_N PF00440.23 ABK75097.1 - 1.3e-16 60.1 0.1 3.5e-16 58.7 0.1 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 ABK75097.1 - 3.3e-09 37.0 0.2 6.4e-09 36.1 0.2 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain DUF3670 PF12419.8 ABK75097.1 - 0.039 13.8 0.8 0.078 12.8 0.4 1.8 1 1 1 2 2 2 0 SNF2 Helicase protein TetR_C_31 PF17940.1 ABK75097.1 - 0.053 13.7 0.8 0.053 13.7 0.8 2.7 2 2 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain GFO_IDH_MocA PF01408.22 ABK75098.1 - 5.7e-08 33.6 0.2 1.2e-07 32.6 0.2 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold SAF PF08666.12 ABK75098.1 - 2.3e-07 31.3 0.0 4.8e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 SAF domain NAD_binding_3 PF03447.16 ABK75098.1 - 4e-07 30.7 0.2 1.1e-06 29.2 0.3 1.7 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain Acyl-CoA_dh_1 PF00441.24 ABK75099.1 - 1.2e-19 71.0 2.4 1.7e-19 70.5 1.7 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK75099.1 - 4.9e-12 46.5 0.2 1.9e-11 44.6 0.2 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ABK75099.1 - 7.3e-08 32.8 1.5 1.8e-07 31.5 1.5 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK75099.1 - 0.00077 19.6 0.1 0.0028 17.8 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain MMPL PF03176.15 ABK75100.1 - 4.9e-83 278.8 33.9 2.2e-48 164.9 14.4 2.2 2 0 0 2 2 2 2 MMPL family Pkinase PF00069.25 ABK75101.1 - 1.1e-46 159.4 0.0 1.5e-46 158.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ABK75101.1 - 1.5e-32 112.9 0.0 2.2e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ABK75101.1 - 2.6e-06 27.0 0.0 3.7e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ABK75101.1 - 4e-06 26.9 4.0 0.0019 18.2 0.0 3.2 2 2 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ABK75101.1 - 0.00081 18.3 0.0 0.0011 17.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ABK75101.1 - 0.0035 16.7 0.0 0.0076 15.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 ABK75101.1 - 0.0048 15.9 0.0 0.0066 15.4 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 ABK75101.1 - 0.02 14.5 0.0 0.042 13.4 0.0 1.4 2 0 0 2 2 2 0 RIO1 family DUF3999 PF13163.6 ABK75101.1 - 0.021 14.0 2.8 0.033 13.4 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3999) ABC1 PF03109.16 ABK75101.1 - 0.031 14.4 0.0 0.088 13.0 0.0 1.6 1 1 0 1 1 1 0 ABC1 family NUDIX PF00293.28 ABK75102.1 - 3.7e-11 43.2 0.0 6.2e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Cupin_2 PF07883.11 ABK75103.1 - 0.00015 21.4 0.1 0.00033 20.3 0.0 1.6 1 1 0 1 1 1 1 Cupin domain TPP_enzyme_N PF02776.18 ABK75104.1 - 1.2e-55 187.7 0.2 3.1e-55 186.4 0.2 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 ABK75104.1 - 2e-52 176.6 0.4 3.6e-52 175.7 0.4 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 ABK75104.1 - 6.2e-50 168.9 0.0 1.8e-49 167.5 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.16 ABK75104.1 - 0.018 14.8 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit POR_N PF01855.19 ABK75104.1 - 0.047 13.4 0.7 0.089 12.5 0.2 1.7 2 0 0 2 2 2 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg ABC_tran PF00005.27 ABK75105.1 - 1.3e-29 103.5 0.0 1.7e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 ABK75105.1 - 7.2e-20 71.3 0.0 1.4e-19 70.4 0.0 1.5 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 ABK75105.1 - 5.1e-07 29.8 1.0 0.00012 22.0 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ABK75105.1 - 3.6e-05 24.1 0.6 0.00052 20.3 0.6 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ABK75105.1 - 0.0026 18.1 0.7 0.0098 16.3 0.6 1.9 2 1 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 ABK75105.1 - 0.0027 17.2 0.4 0.2 11.1 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.18 ABK75105.1 - 0.0063 15.9 0.1 0.016 14.6 0.1 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_29 PF13555.6 ABK75105.1 - 0.03 14.1 0.1 0.055 13.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 ABK75105.1 - 0.057 13.5 0.3 0.1 12.6 0.3 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain Roc PF08477.13 ABK75105.1 - 0.083 13.1 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 ABK75105.1 - 0.22 11.2 0.1 0.66 9.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain LysR_substrate PF03466.20 ABK75106.1 - 2.7e-22 79.2 5.3 3.8e-22 78.7 5.3 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 ABK75106.1 - 3.3e-18 65.4 0.2 1.3e-17 63.5 0.2 2.1 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 ABK75106.1 - 0.0089 15.9 2.5 0.012 15.4 0.1 2.5 3 0 0 3 3 3 1 MarR family MrpF_PhaF PF04066.13 ABK75107.1 - 4.8e-11 42.9 6.6 4.8e-11 42.9 6.6 1.7 2 0 0 2 2 2 1 Multiple resistance and pH regulation protein F (MrpF / PhaF) CMD PF02627.20 ABK75108.1 - 3.7e-10 39.7 0.1 5.7e-10 39.1 0.1 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family GCN5L1 PF06320.13 ABK75108.1 - 0.076 13.2 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) NiFeSe_Hases PF00374.19 ABK75109.1 - 1.2e-82 278.4 0.0 6.5e-61 206.8 0.0 2.2 2 0 0 2 2 2 2 Nickel-dependent hydrogenase Aminotran_3 PF00202.21 ABK75110.1 - 4e-107 358.4 0.4 4.6e-107 358.2 0.4 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 ABK75110.1 - 1.3e-08 34.5 0.0 5e-08 32.6 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 ABK75110.1 - 0.0039 16.4 0.0 0.0095 15.1 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 ABK75110.1 - 0.14 11.1 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V PAP_PilO PF06864.12 ABK75111.1 - 0.0018 17.2 0.1 0.0026 16.6 0.1 1.3 1 0 0 1 1 1 1 Pilin accessory protein (PilO) DUF4006 PF13179.6 ABK75111.1 - 0.0033 17.3 0.2 0.0069 16.3 0.2 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF4006) TPR_21 PF09976.9 ABK75111.1 - 0.0091 15.7 0.1 0.014 15.1 0.1 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain VirB8 PF04335.13 ABK75111.1 - 0.013 15.3 3.2 0.048 13.5 0.6 2.0 2 0 0 2 2 2 0 VirB8 protein Regulator_TrmB PF11495.8 ABK75111.1 - 0.029 13.5 0.2 0.044 13.0 0.2 1.2 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB Neuregulin PF02158.15 ABK75111.1 - 0.036 13.4 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 Neuregulin intracellular region DUF4307 PF14155.6 ABK75111.1 - 7.4 6.5 11.0 1.8 8.4 0.6 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4307) Shikimate_dh_N PF08501.11 ABK75112.1 - 4.3e-20 71.8 0.0 6.8e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain ThiF PF00899.21 ABK75112.1 - 0.00081 18.8 1.6 0.0015 18.0 1.6 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 ABK75112.1 - 0.005 16.9 0.0 0.0079 16.3 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 ABK75112.1 - 0.15 12.1 0.0 23 5.0 0.1 2.2 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ELFV_dehydrog PF00208.21 ABK75112.1 - 0.3 10.8 2.0 0.44 10.2 1.2 1.6 1 1 1 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Abhydrolase_3 PF07859.13 ABK75113.1 - 9.9e-45 153.0 0.6 1.3e-44 152.6 0.6 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ABK75113.1 - 2.2e-07 30.6 0.5 1.2e-06 28.2 0.5 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 ABK75113.1 - 9.2e-06 24.7 0.0 1.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase DLH PF01738.18 ABK75113.1 - 0.00088 18.9 0.0 1.3 8.5 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 ABK75113.1 - 0.0021 17.9 0.0 0.0054 16.6 0.0 1.6 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Esterase PF00756.20 ABK75113.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.8 ABK75113.1 - 0.014 14.7 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Thioesterase PF00975.20 ABK75113.1 - 0.022 14.9 0.1 0.03 14.4 0.1 1.2 1 0 0 1 1 1 0 Thioesterase domain Peptidase_S15 PF02129.18 ABK75113.1 - 0.15 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Lipase_3 PF01764.25 ABK75113.1 - 0.19 11.6 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) adh_short_C2 PF13561.6 ABK75114.1 - 3.5e-48 164.2 5.5 3.4e-47 161.0 5.5 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK75114.1 - 1.4e-46 158.5 1.2 1.1e-45 155.5 1.2 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK75114.1 - 9.2e-12 45.2 0.1 1.4e-11 44.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Hormone_3 PF00159.18 ABK75114.1 - 4.5 7.4 5.4 1.2 9.3 1.5 2.0 2 0 0 2 2 2 0 Pancreatic hormone peptide Mce4_CUP1 PF11887.8 ABK75115.1 - 4.6e-14 52.5 0.0 6.2e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative MlaD PF02470.20 ABK75115.1 - 5.9e-08 32.9 0.1 1.1e-07 32.0 0.1 1.5 1 0 0 1 1 1 1 MlaD protein HBM PF16591.5 ABK75115.1 - 0.026 14.0 0.6 2.5 7.5 0.0 2.1 1 1 1 2 2 2 0 Helical bimodular sensor domain TetR_C_31 PF17940.1 ABK75115.1 - 2.9 8.1 8.6 0.16 12.2 1.7 2.4 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Fer4_13 PF13370.6 ABK75116.1 - 2.3e-11 44.0 0.1 2.6e-11 43.9 0.1 1.0 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 ABK75116.1 - 1.5e-09 38.4 1.1 1.8e-09 38.2 1.1 1.1 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_19 PF06902.11 ABK75116.1 - 4.2e-07 30.0 0.1 4.6e-07 29.8 0.1 1.1 1 0 0 1 1 1 1 Divergent 4Fe-4S mono-cluster Fer4_2 PF12797.7 ABK75116.1 - 0.17 12.0 0.1 0.17 12.0 0.1 2.1 3 0 0 3 3 3 0 4Fe-4S binding domain ABC_tran PF00005.27 ABK75117.1 - 3.5e-35 121.5 0.0 5.4e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 ABK75117.1 - 2.7e-12 46.7 3.6 2.7e-12 46.7 3.6 3.2 5 0 0 5 5 4 1 TOBE domain AAA_21 PF13304.6 ABK75117.1 - 1.9e-09 37.8 0.0 0.00078 19.3 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK75117.1 - 8.6e-06 25.3 0.1 0.035 13.5 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain TOBE PF03459.17 ABK75117.1 - 2.4e-05 24.6 3.0 2.4e-05 24.6 3.0 2.3 3 0 0 3 3 2 1 TOBE domain AAA PF00004.29 ABK75117.1 - 7.1e-05 23.3 0.0 0.00092 19.6 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ABK75117.1 - 0.00017 22.0 1.3 0.00083 19.8 1.3 2.0 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 ABK75117.1 - 0.0013 18.7 0.0 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase TOBE_3 PF12857.7 ABK75117.1 - 0.0018 18.1 1.9 0.003 17.4 0.7 2.1 2 0 0 2 2 1 1 TOBE-like domain AAA_29 PF13555.6 ABK75117.1 - 0.0036 17.0 0.0 0.0086 15.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 ABK75117.1 - 0.0058 16.9 0.0 0.018 15.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 ABK75117.1 - 0.0091 16.5 0.0 0.015 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 ABK75117.1 - 0.018 15.3 0.4 0.08 13.2 0.0 2.1 1 1 1 2 2 2 0 AAA domain IstB_IS21 PF01695.17 ABK75117.1 - 0.02 14.6 0.1 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein Rad17 PF03215.15 ABK75117.1 - 0.023 14.6 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 ABK75117.1 - 0.031 14.2 0.1 0.06 13.3 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 ABK75117.1 - 0.042 14.0 0.0 0.08 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 ABK75117.1 - 0.11 12.5 0.1 0.29 11.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 ABK75117.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 ABK75117.1 - 0.13 12.1 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_15 PF13175.6 ABK75117.1 - 0.2 11.3 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain CysA_C_terminal PF17850.1 ABK75117.1 - 0.28 11.8 3.0 1.9 9.1 0.1 3.4 3 0 0 3 3 3 0 CysA C-terminal regulatory domain Dioxygenase_C PF00775.21 ABK75118.1 - 4.4e-47 159.9 0.0 5.6e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 ABK75118.1 - 1e-32 111.8 0.3 1.5e-32 111.2 0.3 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 ABK75118.1 - 0.0053 17.0 0.1 0.035 14.4 0.0 2.2 2 1 0 2 2 2 1 Carboxypeptidase regulatory-like domain COesterase PF00135.28 ABK75119.1 - 1.9e-115 386.6 0.0 2.4e-115 386.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ABK75119.1 - 1.6e-14 54.3 3.1 5.9e-14 52.4 3.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ABK75119.1 - 0.002 17.6 0.0 0.0036 16.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family CMD PF02627.20 ABK75120.1 - 1.2e-11 44.4 0.1 1.9e-11 43.8 0.1 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family PA26 PF04636.13 ABK75120.1 - 0.011 14.6 0.0 0.015 14.3 0.0 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SnoaL_4 PF13577.6 ABK75121.1 - 0.026 14.7 0.4 0.031 14.4 0.4 1.2 1 0 0 1 1 1 0 SnoaL-like domain ADH_N PF08240.12 ABK75122.1 - 8.7e-27 93.2 1.0 1.4e-26 92.5 1.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ABK75122.1 - 9.5e-20 70.9 0.4 1.7e-19 70.1 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ABK75122.1 - 0.00045 21.3 0.0 0.00082 20.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NADH_4Fe-4S PF10589.9 ABK75122.1 - 0.049 13.7 0.2 0.11 12.6 0.2 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region HTH_3 PF01381.22 ABK75123.1 - 3.3e-13 49.5 0.1 4.6e-13 49.0 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 ABK75123.1 - 4.5e-12 46.1 7.4 7.9e-12 45.4 7.4 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Cupin_2 PF07883.11 ABK75123.1 - 6.3e-12 45.0 0.1 1.2e-11 44.1 0.1 1.5 1 0 0 1 1 1 1 Cupin domain HTH_19 PF12844.7 ABK75123.1 - 1.6e-10 40.8 0.0 2.8e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 ABK75123.1 - 2.3e-10 40.8 0.2 3.7e-10 40.1 0.2 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 ABK75123.1 - 2.3e-06 27.4 1.0 3.8e-06 26.7 1.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 ABK75123.1 - 0.00011 22.0 0.3 0.00019 21.3 0.3 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain TnsD PF15978.5 ABK75123.1 - 0.012 14.7 0.0 0.014 14.4 0.0 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D HTH_AraC PF00165.23 ABK75123.1 - 0.075 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family DUF2083 PF09856.9 ABK75124.1 - 4.4e-69 231.3 0.1 8.9e-69 230.3 0.0 1.5 2 0 0 2 2 2 1 Predicted transcriptional regulator (DUF2083) Peptidase_M78 PF06114.13 ABK75124.1 - 1.8e-20 73.1 0.1 6.1e-20 71.4 0.0 1.8 2 0 0 2 2 2 1 IrrE N-terminal-like domain HTH_31 PF13560.6 ABK75124.1 - 7e-14 51.9 0.1 2.4e-13 50.2 0.1 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 ABK75124.1 - 2.2e-13 50.1 0.0 5e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 ABK75124.1 - 7.9e-11 41.8 0.0 7.4e-10 38.7 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_25 PF13413.6 ABK75124.1 - 3.8e-05 23.5 0.9 8.6e-05 22.3 0.9 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 ABK75124.1 - 0.0016 18.8 0.0 0.0041 17.5 0.0 1.7 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain Sigma70_r4 PF04545.16 ABK75124.1 - 0.0092 15.5 0.1 0.025 14.1 0.1 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 YdaS_antitoxin PF15943.5 ABK75124.1 - 0.014 15.3 0.0 0.18 11.7 0.0 2.7 2 1 1 3 3 3 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_24 PF13412.6 ABK75124.1 - 0.02 14.5 0.1 0.051 13.1 0.1 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_37 PF13744.6 ABK75124.1 - 0.041 13.8 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain MarR_2 PF12802.7 ABK75124.1 - 0.38 10.7 0.1 0.38 10.7 0.1 2.5 3 0 0 3 3 3 0 MarR family NHase_beta PF02211.15 ABK75125.1 - 0.00089 19.3 0.0 0.00089 19.3 0.0 1.1 1 0 0 1 1 1 1 Nitrile hydratase beta subunit SHOCT PF09851.9 ABK75125.1 - 0.0078 15.9 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Short C-terminal domain CwsA PF10814.8 ABK75126.1 - 2.6e-47 160.3 15.4 5.7e-47 159.2 15.4 1.5 1 1 0 1 1 1 1 Cell wall synthesis protein CwsA UCR_Fe-S_N PF10399.9 ABK75126.1 - 0.0024 17.2 1.9 0.0024 17.2 1.9 2.3 2 0 0 2 2 2 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF3995 PF13160.6 ABK75126.1 - 0.021 15.2 0.9 0.037 14.4 0.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3995) DUF4366 PF14283.6 ABK75126.1 - 0.036 14.1 0.0 0.045 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Herpes_UL14 PF03580.14 ABK75126.1 - 0.088 13.1 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL14-like protein ThiS PF02597.20 ABK75127.1 - 1.2e-10 41.9 0.0 1.3e-10 41.7 0.0 1.0 1 0 0 1 1 1 1 ThiS family adh_short_C2 PF13561.6 ABK75128.1 - 5e-50 170.2 1.4 5.6e-50 170.1 1.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK75128.1 - 6e-39 133.5 0.1 7.2e-39 133.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK75128.1 - 4.2e-06 26.8 0.7 6e-06 26.3 0.7 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK75128.1 - 0.0036 16.8 0.0 0.0067 15.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family rhaM PF05336.13 ABK75129.1 - 2.1e-28 98.5 0.1 2.3e-28 98.4 0.1 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase Tachylectin PF14517.6 ABK75129.1 - 0.12 11.9 0.0 0.14 11.7 0.0 1.0 1 0 0 1 1 1 0 Tachylectin Sulfatase PF00884.23 ABK75130.1 - 6.6e-96 321.3 0.0 8.6e-96 321.0 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 ABK75130.1 - 0.00025 20.7 0.0 0.084 12.4 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Laminin_G_2 PF02210.24 ABK75130.1 - 0.019 15.6 0.0 0.042 14.4 0.0 1.6 1 0 0 1 1 1 0 Laminin G domain VanY PF02557.17 ABK75131.1 - 2.7e-13 49.8 0.2 2.3e-12 46.9 0.2 2.0 1 1 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Peptidase_M15_2 PF05951.13 ABK75131.1 - 0.0023 17.6 0.0 0.0068 16.1 0.0 1.7 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF882) Peptidase_M15_3 PF08291.11 ABK75131.1 - 0.0089 16.1 0.0 0.55 10.3 0.0 2.2 2 0 0 2 2 2 1 Peptidase M15 Blt1 PF12754.7 ABK75131.1 - 0.059 13.7 0.0 0.072 13.4 0.0 1.2 1 0 0 1 1 1 0 Blt1 N-terminal domain ANTAR PF03861.14 ABK75132.1 - 7.6e-19 67.3 0.4 7.6e-19 67.3 0.4 2.1 2 0 0 2 2 2 1 ANTAR domain GAF_2 PF13185.6 ABK75132.1 - 1.1e-09 38.8 0.2 1.4e-09 38.3 0.2 1.2 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 ABK75132.1 - 0.0029 18.2 0.0 0.004 17.8 0.0 1.2 1 0 0 1 1 1 1 GAF domain F420H2_quin_red PF04075.14 ABK75133.1 - 9.3e-05 22.6 0.0 0.00012 22.2 0.0 1.3 1 1 0 1 1 1 1 F420H(2)-dependent quinone reductase FAD-oxidase_C PF02913.19 ABK75134.1 - 3.5e-63 213.5 1.1 3.8e-63 213.4 0.4 1.4 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 ABK75134.1 - 6.1e-40 136.2 3.4 1.4e-39 135.0 3.4 1.6 1 0 0 1 1 1 1 FAD binding domain SSP160 PF06933.11 ABK75136.1 - 0.15 10.3 10.3 0.16 10.2 10.3 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 B277 PF17623.2 ABK75136.1 - 1.4 7.9 3.4 1.5 7.9 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function Dicty_REP PF05086.12 ABK75136.1 - 9 4.1 4.8 10 3.9 4.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sugar-bind PF04198.13 ABK75137.1 - 1e-50 172.3 1.0 1.5e-50 171.7 1.0 1.2 1 0 0 1 1 1 1 Putative sugar-binding domain Sigma70_r4 PF04545.16 ABK75137.1 - 2.2e-05 23.9 0.8 0.00013 21.4 0.5 2.3 3 0 0 3 3 3 1 Sigma-70, region 4 HTH_28 PF13518.6 ABK75137.1 - 0.00055 20.0 0.2 0.0018 18.4 0.2 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain DeoRC PF00455.22 ABK75137.1 - 0.0021 18.0 1.4 0.0063 16.5 0.1 2.0 2 0 0 2 2 2 1 DeoR C terminal sensor domain HTH_23 PF13384.6 ABK75137.1 - 0.0067 16.2 0.0 0.021 14.6 0.0 2.0 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.15 ABK75137.1 - 0.026 14.6 0.0 0.055 13.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase TrmB PF01978.19 ABK75137.1 - 0.091 12.7 0.0 0.49 10.3 0.0 2.2 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB YqaH PF17448.2 ABK75137.1 - 0.12 12.7 0.0 1.2 9.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized YqaH-like DUF1304 PF06993.12 ABK75138.1 - 3e-33 114.1 9.4 3.9e-33 113.7 9.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1304) TmoB PF06234.12 ABK75139.1 - 0.0079 16.3 1.1 0.014 15.4 1.1 1.3 1 0 0 1 1 1 1 Toluene-4-monooxygenase system protein B (TmoB) zinc_ribbon_2 PF13240.6 ABK75139.1 - 0.14 11.9 1.7 1.6 8.5 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_recom PF13408.6 ABK75139.1 - 0.25 11.9 1.7 0.56 10.8 0.2 2.1 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain SnoaL_4 PF13577.6 ABK75140.1 - 0.0015 18.6 0.0 0.0026 17.9 0.0 1.6 1 1 0 1 1 1 1 SnoaL-like domain Glyoxalase_6 PF18029.1 ABK75141.1 - 1.7e-25 89.8 10.2 2e-11 44.6 0.1 4.0 3 2 0 3 3 3 3 Glyoxalase-like domain Glyoxalase PF00903.25 ABK75141.1 - 2.4e-19 69.8 0.9 3.3e-05 24.1 0.0 5.4 4 2 0 4 4 4 4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ABK75141.1 - 2.3e-09 37.5 1.7 0.88 9.9 0.1 5.2 3 2 2 5 5 5 5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Adhesin_P1_N PF18652.1 ABK75141.1 - 0.049 13.6 0.8 0.48 10.5 0.0 2.3 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain PALP PF00291.25 ABK75142.1 - 1.2e-63 215.3 0.3 1.6e-63 214.9 0.3 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 ABK75142.1 - 1.1e-17 64.2 0.3 1e-07 32.3 0.0 2.7 2 0 0 2 2 2 2 CBS domain OTT_1508_deam PF14441.6 ABK75143.1 - 0.14 12.2 1.0 0.37 10.8 1.0 1.6 1 0 0 1 1 1 0 OTT_1508-like deaminase Bac_luciferase PF00296.20 ABK75144.1 - 4.8e-38 131.3 11.9 6e-38 131.0 11.9 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase ECH_1 PF00378.20 ABK75145.1 - 4.3e-38 131.1 0.0 5.1e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK75145.1 - 2.3e-27 96.4 0.0 2.6e-27 96.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Bac_luciferase PF00296.20 ABK75146.1 - 2.8e-50 171.6 0.0 3.6e-47 161.3 0.0 2.0 1 1 1 2 2 2 2 Luciferase-like monooxygenase APH PF01636.23 ABK75148.1 - 6e-38 131.1 8.2 8.6e-38 130.6 8.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family acVLRF1 PF18859.1 ABK75148.1 - 0.88 9.9 7.0 1.5 9.1 0.4 2.7 2 1 1 3 3 3 0 Actinobacteria/chloroflexi VLRF1 release factor LysR_substrate PF03466.20 ABK75149.1 - 3.7e-37 127.7 3.9 5.9e-37 127.1 3.9 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 ABK75149.1 - 7.8e-18 64.2 2.2 4.5e-17 61.8 1.1 2.4 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 ABK75149.1 - 0.003 17.4 0.0 0.0092 15.8 0.0 1.9 1 0 0 1 1 1 1 MarR family HTH_30 PF13556.6 ABK75149.1 - 0.011 15.5 0.1 0.03 14.1 0.1 1.7 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_24 PF13412.6 ABK75149.1 - 0.018 14.6 0.1 0.04 13.5 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_Tnp_ISL3 PF13542.6 ABK75149.1 - 0.02 14.3 0.2 0.05 13.0 0.2 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 ABK75149.1 - 0.026 14.3 0.3 0.091 12.6 0.1 2.0 1 1 1 2 2 2 0 Homeodomain-like domain HTH_IclR PF09339.10 ABK75149.1 - 0.048 13.5 0.1 0.21 11.4 0.1 2.0 2 0 0 2 2 2 0 IclR helix-turn-helix domain DUF905 PF06006.12 ABK75149.1 - 0.052 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF905) HTH_8 PF02954.19 ABK75149.1 - 0.052 13.3 0.1 0.094 12.5 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family HTH_11 PF08279.12 ABK75149.1 - 0.062 13.3 0.1 0.46 10.5 0.0 2.3 2 0 0 2 2 2 0 HTH domain HATPase_c PF02518.26 ABK75150.1 - 5.3e-20 72.0 0.0 1e-19 71.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ABK75150.1 - 4.7e-15 55.4 3.2 5.5e-15 55.2 1.3 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 ABK75150.1 - 3.5e-13 49.7 0.8 1.1e-12 48.2 0.6 2.0 1 1 0 1 1 1 1 HAMP domain HATPase_c_2 PF13581.6 ABK75150.1 - 0.00051 20.0 0.0 0.0016 18.4 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain DUF4132 PF13569.6 ABK75150.1 - 0.089 12.6 0.2 0.29 10.9 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4132) Lyase_1 PF00206.20 ABK75151.1 - 3.3e-102 342.1 0.0 4.7e-102 341.6 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 ABK75151.1 - 6e-19 68.2 2.1 2.1e-18 66.5 0.2 2.7 3 0 0 3 3 3 1 Fumarase C C-terminus DUF2807 PF10988.8 ABK75151.1 - 0.02 14.7 1.3 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 Putative auto-transporter adhesin, head GIN domain HCMV_UL124 PF17609.2 ABK75151.1 - 0.067 13.4 1.4 0.13 12.4 1.4 1.4 1 0 0 1 1 1 0 Family of unknown function Amidohydro_2 PF04909.14 ABK75152.1 - 1.3e-38 133.5 1.1 1.5e-38 133.2 1.1 1.1 1 0 0 1 1 1 1 Amidohydrolase PQQ_3 PF13570.6 ABK75153.1 - 1.2e-14 54.2 23.1 0.00054 20.4 0.3 7.0 7 0 0 7 7 7 5 PQQ-like domain PQQ_2 PF13360.6 ABK75153.1 - 6.3e-13 48.9 9.9 4e-09 36.4 3.0 3.4 2 2 1 3 3 3 3 PQQ-like domain PQQ PF01011.21 ABK75153.1 - 8.7e-05 22.3 5.1 0.00062 19.6 0.1 4.3 4 0 0 4 4 4 1 PQQ enzyme repeat DUF1899 PF08953.11 ABK75153.1 - 0.0084 16.0 0.1 0.017 15.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) T2SS-T3SS_pil_N PF13629.6 ABK75153.1 - 0.14 11.9 0.2 0.73 9.6 0.0 2.3 3 0 0 3 3 3 0 Pilus formation protein N terminal region HTH_18 PF12833.7 ABK75155.1 - 3.6e-23 81.6 0.2 5.4e-23 81.1 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 ABK75155.1 - 9.4e-14 51.1 0.0 6.5e-07 29.3 0.0 2.2 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_5 PF01022.20 ABK75155.1 - 0.0058 16.5 0.1 2 8.3 0.0 2.7 2 1 0 2 2 2 2 Bacterial regulatory protein, arsR family FCD PF07729.12 ABK75156.1 - 1.4e-23 83.7 6.1 2.2e-23 83.0 6.1 1.3 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 ABK75156.1 - 9.2e-16 57.3 0.9 2.5e-15 55.9 0.9 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_11 PF08279.12 ABK75156.1 - 0.00019 21.3 0.1 0.00057 19.8 0.0 1.8 2 0 0 2 2 2 1 HTH domain TrmB PF01978.19 ABK75156.1 - 0.0015 18.4 0.1 0.0033 17.3 0.1 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_41 PF14502.6 ABK75156.1 - 0.0089 15.7 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_27 PF13463.6 ABK75156.1 - 0.011 16.2 0.2 0.036 14.6 0.1 1.9 2 0 0 2 2 2 0 Winged helix DNA-binding domain HTH_5 PF01022.20 ABK75156.1 - 0.051 13.5 0.1 0.25 11.2 0.0 2.3 2 1 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_DeoR PF08220.12 ABK75156.1 - 0.065 13.0 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Rrf2 PF02082.20 ABK75156.1 - 0.079 13.3 0.0 0.23 11.8 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator Ribosomal_S19e PF01090.19 ABK75156.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein S19e SIR2 PF02146.17 ABK75157.1 - 1e-39 136.3 0.0 1.5e-39 135.7 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 ABK75157.1 - 0.05 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain Glyoxalase PF00903.25 ABK75158.1 - 1.7e-16 60.6 0.0 1.9e-16 60.4 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ABK75158.1 - 6.1e-07 30.2 0.2 1.1e-06 29.3 0.2 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 ABK75158.1 - 4.7e-06 26.5 0.0 0.009 15.9 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.6 ABK75158.1 - 0.015 15.5 0.0 0.023 14.9 0.0 1.3 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 ABK75158.1 - 0.055 13.6 0.3 1.4 9.1 0.3 2.1 1 1 0 1 1 1 0 Glyoxalase-like domain 3HCDH_N PF02737.18 ABK75159.1 - 1e-48 165.6 1.0 1.4e-48 165.2 1.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 ABK75159.1 - 3.8e-27 94.7 0.0 7.4e-27 93.8 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_7 PF13241.6 ABK75159.1 - 0.00096 19.6 0.1 0.0018 18.7 0.1 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.23 ABK75159.1 - 0.0037 17.3 0.5 0.0083 16.1 0.1 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DFP PF04127.15 ABK75159.1 - 0.0056 16.5 0.4 0.0056 16.5 0.4 1.7 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein NAD_binding_2 PF03446.15 ABK75159.1 - 0.0067 16.6 2.5 0.02 15.1 1.3 2.3 1 1 1 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ABK75159.1 - 0.0085 16.6 0.1 0.027 15.1 0.1 2.0 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 ABK75159.1 - 0.017 15.4 0.7 0.051 13.8 0.1 2.1 2 0 0 2 2 2 0 TrkA-N domain DAO PF01266.24 ABK75159.1 - 0.44 10.1 5.4 1 8.9 5.4 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase SnoaL_2 PF12680.7 ABK75160.1 - 6.4e-09 36.4 3.2 9.2e-09 35.9 2.8 1.5 1 1 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 ABK75160.1 - 0.037 13.8 0.2 0.13 12.1 0.1 2.0 1 1 1 2 2 2 0 SnoaL-like polyketide cyclase WXG100 PF06013.12 ABK75161.1 - 2.1e-19 69.5 2.4 2.1e-19 69.5 2.4 2.4 2 1 0 2 2 2 1 Proteins of 100 residues with WXG T7SS_ESX_EspC PF10824.8 ABK75161.1 - 3.7e-08 33.8 2.7 3.7e-08 33.8 2.7 3.1 2 1 1 3 3 3 1 Excreted virulence factor EspC, type VII ESX diderm FCSD-flav_bind PF09242.11 ABK75161.1 - 0.09 13.1 1.5 0.25 11.7 1.5 1.7 1 0 0 1 1 1 0 Flavocytochrome c sulphide dehydrogenase, flavin-binding ATG_C PF09333.11 ABK75161.1 - 0.65 10.4 4.1 0.43 11.0 0.5 2.4 3 0 0 3 3 3 0 Autophagy-related protein C terminal domain EthD PF07110.11 ABK75162.1 - 2.4e-07 31.8 1.4 6.1e-07 30.5 1.4 1.6 1 1 0 1 1 1 1 EthD domain MmlI PF09448.10 ABK75162.1 - 0.099 13.1 0.0 0.17 12.3 0.0 1.4 1 1 0 1 1 1 0 Methylmuconolactone methyl-isomerase Hexapep PF00132.24 ABK75163.1 - 1.3e-22 78.5 6.7 5.6e-06 25.9 0.0 5.3 3 2 2 5 5 5 5 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 ABK75163.1 - 2.6e-18 66.9 1.5 2.6e-18 66.9 1.5 2.1 2 0 0 2 2 2 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 ABK75163.1 - 2.2e-15 56.9 0.0 2.9e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.6 ABK75163.1 - 1.7e-09 37.3 4.6 0.19 11.5 0.1 6.2 6 0 0 6 6 6 3 Hexapeptide repeat of succinyl-transferase IspD PF01128.19 ABK75163.1 - 2.3e-09 37.3 3.5 2.3e-09 37.3 3.5 1.8 2 1 0 2 2 2 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Rnk_N PF14760.6 ABK75163.1 - 0.053 14.0 0.3 0.27 11.7 0.5 2.2 2 0 0 2 2 2 0 Rnk N-terminus SBP_bac_5 PF00496.22 ABK75164.1 - 2.1e-56 191.5 1.2 2.8e-56 191.1 1.2 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle MlaD PF02470.20 ABK75165.1 - 3.8e-11 43.1 0.0 8.8e-11 42.0 0.0 1.6 2 0 0 2 2 2 1 MlaD protein Mce4_CUP1 PF11887.8 ABK75165.1 - 3e-05 23.6 4.3 4.9e-05 22.9 4.3 1.2 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative ATG16 PF08614.11 ABK75165.1 - 0.0079 16.4 0.5 0.012 15.9 0.5 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) AAA_13 PF13166.6 ABK75165.1 - 0.0089 14.7 0.1 0.011 14.4 0.1 1.0 1 0 0 1 1 1 1 AAA domain BORCS6 PF10157.9 ABK75165.1 - 0.025 14.8 0.0 0.066 13.4 0.0 1.8 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 6 BLOC1_2 PF10046.9 ABK75165.1 - 0.068 13.5 0.1 1.4 9.2 0.0 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1708 PF08101.11 ABK75165.1 - 0.2 10.8 0.0 9 5.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1708) DUF948 PF06103.11 ABK75165.1 - 1.1 9.6 10.3 0.12 12.6 0.9 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) BPD_transp_1 PF00528.22 ABK75168.1 - 1.1e-16 61.1 18.8 1.1e-16 61.1 18.8 2.5 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF4713 PF15831.5 ABK75168.1 - 0.29 11.6 2.1 0.4 11.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4713) Gmad2 PF10648.9 ABK75169.1 - 9.5e-05 22.6 0.0 0.00018 21.7 0.0 1.4 1 0 0 1 1 1 1 Immunoglobulin-like domain of bacterial spore germination CHAP PF05257.16 ABK75169.1 - 0.01 16.4 0.1 0.026 15.1 0.0 1.7 2 0 0 2 2 2 0 CHAP domain Haem_degrading PF03928.14 ABK75170.1 - 2.4e-33 114.7 0.9 2.7e-33 114.6 0.9 1.0 1 0 0 1 1 1 1 Haem-degrading FMN_red PF03358.15 ABK75171.1 - 4.9e-05 23.1 0.1 7.5e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 ABK75171.1 - 0.042 13.6 0.0 0.19 11.4 0.0 1.9 1 1 0 1 1 1 0 Flavodoxin-like fold DNA_pol_lambd_f PF10391.9 ABK75172.1 - 0.15 11.9 0.1 0.44 10.4 0.0 1.8 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda HAD_2 PF13419.6 ABK75173.1 - 9.7e-15 55.1 0.0 2.6e-14 53.7 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ABK75173.1 - 2.4e-13 50.9 0.2 3.2e-12 47.2 0.2 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ABK75173.1 - 7.3e-05 22.8 0.1 0.00015 21.7 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 ABK75173.1 - 0.022 15.2 0.3 0.037 14.4 0.3 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 ABK75173.1 - 0.075 13.2 0.0 0.44 10.7 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase FAD_binding_5 PF00941.21 ABK75175.1 - 6.1e-47 159.5 0.1 9.1e-47 159.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 ABK75175.1 - 2.1e-16 60.0 0.3 4e-16 59.0 0.3 1.5 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Molybdopterin PF00384.22 ABK75176.1 - 1.1e-130 436.5 0.0 1.4e-130 436.1 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 ABK75176.1 - 1.8e-18 66.6 0.0 4e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 ABK75176.1 - 0.028 14.4 0.1 0.087 12.8 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin oxidoreductase Fe4S4 domain Acyl-CoA_dh_1 PF00441.24 ABK75177.1 - 2.3e-22 79.8 2.9 4.1e-22 79.0 2.9 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK75177.1 - 9.2e-09 36.0 0.0 2.2e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ABK75177.1 - 1.8e-08 34.5 0.0 3.8e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ABK75177.1 - 1.5e-06 28.5 1.1 3.7e-06 27.2 0.5 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF1326 PF07040.11 ABK75177.1 - 0.024 14.7 0.2 0.059 13.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1326) tRNA-synt_1 PF00133.22 ABK75178.1 - 2.2e-179 597.6 0.0 2.8e-179 597.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 ABK75178.1 - 2.9e-22 79.3 0.0 5.2e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 ABK75178.1 - 7.1e-18 64.5 0.0 1.9e-06 26.9 0.0 3.8 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 ABK75178.1 - 0.0004 19.8 0.0 0.0031 16.9 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain AMP-binding PF00501.28 ABK75179.1 - 1.6e-63 214.8 0.0 1.9e-63 214.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK75179.1 - 6.7e-11 43.0 0.4 1.8e-10 41.6 0.4 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TetR_N PF00440.23 ABK75180.1 - 2.7e-10 39.8 0.0 5.8e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_3 PF01381.22 ABK75180.1 - 0.0007 19.6 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_7 PF02796.15 ABK75180.1 - 0.0062 16.6 0.1 0.012 15.6 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_11 PF08279.12 ABK75180.1 - 0.01 15.7 0.0 0.033 14.2 0.0 1.8 2 0 0 2 2 2 0 HTH domain HTH_Tnp_1_2 PF13022.6 ABK75180.1 - 0.014 15.5 0.0 0.026 14.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_35 PF13693.6 ABK75180.1 - 0.017 15.1 0.1 0.67 10.0 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding TetR_C_33 PF13305.6 ABK75180.1 - 0.02 15.6 0.0 0.04 14.7 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HTH_24 PF13412.6 ABK75180.1 - 0.12 11.9 0.0 0.8 9.3 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 ABK75180.1 - 0.13 12.0 0.0 0.36 10.7 0.0 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain Ad_Cy_reg PF16701.5 ABK75180.1 - 0.17 11.6 1.8 2.8 7.6 0.4 2.1 1 1 1 2 2 2 0 Adenylate cyclase regulatory domain RNase_E_G PF10150.9 ABK75182.1 - 4.3e-102 341.2 0.1 5.9e-102 340.7 0.1 1.2 1 0 0 1 1 1 1 Ribonuclease E/G family IF2_N PF04760.15 ABK75182.1 - 4.8e-05 23.1 0.0 0.00011 21.9 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region S1 PF00575.23 ABK75182.1 - 0.00092 19.5 0.1 0.0021 18.3 0.1 1.7 1 0 0 1 1 1 1 S1 RNA binding domain PCB_OB PF17092.5 ABK75182.1 - 0.0018 19.0 1.0 0.011 16.4 0.1 2.8 2 0 0 2 2 2 1 Penicillin-binding protein OB-like domain TENA_THI-4 PF03070.16 ABK75183.1 - 5.2e-44 150.6 0.0 6.3e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 TENA/THI-4/PQQC family FAD_binding_2 PF00890.24 ABK75184.1 - 4.1e-91 306.1 22.0 4.1e-91 306.1 22.0 1.8 2 0 0 2 2 2 1 FAD binding domain Succ_DH_flav_C PF02910.20 ABK75184.1 - 2.6e-10 40.4 1.1 3.1e-08 33.7 1.1 2.3 1 1 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 ABK75184.1 - 1.5e-08 34.2 10.0 7.2e-05 22.2 2.9 3.3 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ABK75184.1 - 5.3e-08 32.0 3.9 6.2e-05 21.9 0.3 3.1 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_3 PF01494.19 ABK75184.1 - 6.5e-05 22.3 6.2 0.0011 18.3 1.6 2.5 3 0 0 3 3 3 2 FAD binding domain Pyr_redox PF00070.27 ABK75184.1 - 0.00041 20.8 2.1 0.037 14.6 0.9 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ABK75184.1 - 0.00071 19.8 3.2 0.0013 19.0 1.7 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 ABK75184.1 - 0.00082 18.7 4.0 0.00082 18.7 4.0 2.0 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 ABK75184.1 - 0.001 18.5 7.9 0.001 18.5 7.9 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 ABK75184.1 - 0.004 16.3 4.9 0.004 16.3 4.9 2.7 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 ABK75184.1 - 0.018 14.3 0.0 0.15 11.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thioredoxin PF00085.20 ABK75185.1 - 8e-32 109.3 0.0 8.8e-32 109.2 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ABK75185.1 - 1.6e-08 35.0 0.1 1.7e-07 31.6 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ABK75185.1 - 9.4e-06 25.9 0.0 0.00019 21.7 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin-like KaiB PF07689.12 ABK75185.1 - 9.7e-05 22.0 0.0 0.00013 21.6 0.0 1.2 1 0 0 1 1 1 1 KaiB domain Thioredoxin_9 PF14595.6 ABK75185.1 - 0.00012 21.9 0.0 0.00014 21.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 ABK75185.1 - 0.00014 21.6 0.1 0.00018 21.3 0.1 1.4 1 1 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 ABK75185.1 - 0.00071 19.7 0.1 0.0011 19.1 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 ABK75185.1 - 0.00091 19.1 0.0 0.0016 18.3 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family TraF PF13728.6 ABK75185.1 - 0.0013 18.6 0.0 0.0016 18.3 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 ABK75185.1 - 0.0049 16.9 0.0 0.0059 16.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain OST3_OST6 PF04756.13 ABK75185.1 - 0.0053 16.2 0.0 0.0063 15.9 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DUF836 PF05768.14 ABK75185.1 - 0.011 16.1 0.0 0.013 15.9 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 ABK75185.1 - 0.015 15.5 0.0 0.026 14.7 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin EKR PF10371.9 ABK75185.1 - 0.03 14.1 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function TPP_enzyme_N PF02776.18 ABK75186.1 - 7.9e-43 146.0 4.3 2.1e-42 144.6 0.8 2.8 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 ABK75186.1 - 4.8e-36 123.5 0.0 9e-36 122.6 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 ABK75186.1 - 1.5e-26 93.0 0.8 5.4e-26 91.2 0.1 2.2 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain ADH_N PF08240.12 ABK75187.1 - 8.3e-10 38.5 0.3 3.5e-08 33.3 0.1 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ABK75187.1 - 1.5e-09 39.0 1.3 3.2e-09 37.9 0.3 2.0 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ABK75187.1 - 2.4e-07 30.8 0.7 5.6e-07 29.6 0.7 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Aldo_ket_red PF00248.21 ABK75188.1 - 4.5e-69 232.9 0.0 5.4e-69 232.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family AP_endonuc_2 PF01261.24 ABK75188.1 - 4.3e-05 23.1 0.2 0.00057 19.4 0.1 2.3 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel DUF3801 PF12687.7 ABK75188.1 - 0.035 14.2 0.0 0.065 13.3 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3801) Polysacc_deac_2 PF04748.13 ABK75188.1 - 0.11 11.7 0.1 2.3 7.4 0.1 2.2 2 0 0 2 2 2 0 Divergent polysaccharide deacetylase 4HBT_2 PF13279.6 ABK75189.1 - 8.4e-07 29.5 0.0 1.1e-06 29.2 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 ABK75189.1 - 6.2e-05 22.4 0.0 0.00013 21.3 0.0 1.5 2 0 0 2 2 2 1 Acyl-ACP thioesterase 4HBT PF03061.22 ABK75189.1 - 0.00097 19.4 0.0 0.0015 18.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily SBP_bac_1 PF01547.25 ABK75191.1 - 6.2e-41 141.4 13.9 9.1e-41 140.8 13.9 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 ABK75191.1 - 3.2e-39 135.5 9.2 4.2e-39 135.1 9.2 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Ca_hom_mod PF14798.6 ABK75191.1 - 0.11 11.5 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 Calcium homeostasis modulator p450 PF00067.22 ABK75192.1 - 1.2e-71 241.8 0.0 1.5e-71 241.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M22 PF00814.25 ABK75193.1 - 4.2e-87 292.3 0.1 5e-87 292.1 0.1 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 ABK75193.1 - 0.0052 16.5 0.0 0.0074 16.0 0.0 1.3 1 1 0 1 1 1 1 Carbamoyltransferase N-terminus ECH_1 PF00378.20 ABK75194.1 - 2.7e-53 180.9 0.2 3e-53 180.7 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK75194.1 - 3.6e-32 112.2 1.8 8.1e-29 101.2 0.5 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Titin_Z PF09042.11 ABK75195.1 - 0.77 9.8 12.3 0.28 11.2 2.7 2.8 2 1 0 2 2 2 0 Titin Z Transformer PF06495.11 ABK75195.1 - 2.8 8.0 20.3 3.1 7.9 20.3 1.0 1 0 0 1 1 1 0 Fruit fly transformer protein FA_desaturase_2 PF03405.14 ABK75196.1 - 8.7e-34 116.8 0.1 1.2e-33 116.3 0.1 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Rubrerythrin PF02915.17 ABK75196.1 - 0.021 15.2 1.0 0.088 13.2 0.5 2.1 1 1 2 3 3 3 0 Rubrerythrin Ribonuc_red_sm PF00268.21 ABK75196.1 - 0.086 12.3 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 Ribonucleotide reductase, small chain Ribosomal_L1 PF00687.21 ABK75196.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L1p/L10e family DUF4129 PF13559.6 ABK75197.1 - 5.5e-14 52.2 4.5 5.5e-14 52.2 4.5 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4129) DUF4381 PF14316.6 ABK75197.1 - 0.0022 18.2 3.9 0.0025 18.1 2.9 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4381) DUF4051 PF13260.6 ABK75197.1 - 0.0034 17.1 2.0 0.0048 16.6 0.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4051) Phage_holin_3_6 PF07332.11 ABK75197.1 - 0.029 14.4 1.1 0.16 12.0 0.2 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III HemY_N PF07219.13 ABK75197.1 - 0.27 11.5 7.5 0.44 10.8 7.5 1.4 1 1 0 1 1 1 0 HemY protein N-terminus Methyltransf_24 PF13578.6 ABK75198.1 - 1.1e-16 61.7 0.0 1.9e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 ABK75198.1 - 2e-09 36.9 0.0 1.3e-08 34.3 0.0 1.9 2 0 0 2 2 2 1 O-methyltransferase CmcI PF04989.12 ABK75198.1 - 0.07 12.8 0.0 0.21 11.3 0.0 1.7 1 1 0 1 1 1 0 Cephalosporin hydroxylase FGE-sulfatase PF03781.16 ABK75199.1 - 2.3e-84 283.0 0.6 2.6e-84 282.8 0.6 1.0 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DUF2530 PF10745.9 ABK75200.1 - 1.6e-32 111.5 4.7 1.9e-32 111.3 4.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2530) DUF3180 PF11377.8 ABK75200.1 - 0.0033 17.6 1.7 0.0041 17.3 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3180) PEP-CTERM PF07589.11 ABK75200.1 - 0.092 12.9 0.1 0.092 12.9 0.1 2.6 3 0 0 3 3 3 0 PEP-CTERM motif Phage_P2_GpE PF06528.12 ABK75200.1 - 0.11 12.1 1.4 0.8 9.3 0.1 2.1 2 0 0 2 2 2 0 Phage P2 GpE DUF308 PF03729.13 ABK75201.1 - 2.7e-26 91.7 57.3 4.9e-12 46.0 19.5 3.0 1 1 2 3 3 3 3 Short repeat of unknown function (DUF308) DUF3180 PF11377.8 ABK75201.1 - 0.031 14.4 3.2 0.031 14.4 3.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3180) DUF3096 PF11295.8 ABK75201.1 - 0.24 11.1 22.1 0.11 12.2 5.5 3.2 2 2 0 2 2 2 0 Protein of unknown function (DUF3096) TMEM100 PF16311.5 ABK75201.1 - 1.1 8.8 20.9 0.84 9.2 4.1 2.7 2 1 1 3 3 3 0 Transmembrane protein 100 Response_reg PF00072.24 ABK75202.1 - 2.7e-32 111.3 0.0 3.6e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 ABK75202.1 - 4.6e-26 90.7 0.1 1.5e-25 89.1 0.1 1.8 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal FleQ PF06490.11 ABK75202.1 - 0.00046 20.5 0.0 0.00063 20.1 0.0 1.2 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ OKR_DC_1_N PF03709.15 ABK75202.1 - 0.0011 19.2 0.0 0.0017 18.6 0.0 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, N-terminal domain DUF485 PF04341.12 ABK75203.1 - 0.012 15.5 2.4 0.016 15.1 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF485 VirB3 PF05101.13 ABK75203.1 - 0.067 13.4 3.4 0.09 13.0 3.4 1.2 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein DUF588 PF04535.12 ABK75203.1 - 0.067 13.0 2.5 0.085 12.6 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF588) AMP-binding PF00501.28 ABK75204.1 - 3.2e-91 306.1 0.1 4.4e-91 305.6 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK75204.1 - 8.3e-22 78.0 0.1 6.6e-21 75.1 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 ABK75205.1 - 5.1e-12 46.0 1.5 6.3e-12 45.7 1.5 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site SpoVS PF04232.12 ABK75205.1 - 0.067 12.9 0.1 0.25 11.1 0.1 2.0 1 1 0 1 1 1 0 Stage V sporulation protein S (SpoVS) UDG PF03167.19 ABK75207.1 - 1.2e-36 126.0 0.0 1.4e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily PEMT PF04191.13 ABK75208.1 - 9.5e-17 61.3 0.5 1.5e-16 60.7 0.5 1.3 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.14 ABK75208.1 - 0.0052 17.2 0.8 0.0052 17.2 0.8 1.8 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF4231 PF14015.6 ABK75208.1 - 0.008 16.6 1.9 0.15 12.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4231) ERG4_ERG24 PF01222.17 ABK75208.1 - 0.011 14.5 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family DAGK_prokar PF01219.19 ABK75208.1 - 0.73 9.7 5.0 0.12 12.3 0.5 1.8 2 0 0 2 2 2 0 Prokaryotic diacylglycerol kinase Semialdhyde_dhC PF02774.18 ABK75210.1 - 3.1e-54 183.9 0.0 4.7e-54 183.3 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 ABK75210.1 - 7.8e-30 103.8 0.0 2e-29 102.5 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 ABK75210.1 - 0.025 14.2 0.0 0.1 12.2 0.0 1.9 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Ldh_1_N PF00056.23 ABK75210.1 - 0.11 12.5 0.0 0.27 11.3 0.0 1.7 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain FCD PF07729.12 ABK75212.1 - 5.8e-24 84.9 9.3 9.9e-24 84.2 9.3 1.3 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 ABK75212.1 - 8.1e-12 44.6 0.2 1.8e-11 43.5 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 ABK75212.1 - 3e-06 26.7 0.0 7.2e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 ABK75212.1 - 0.00017 21.3 0.1 0.00048 19.9 0.1 1.9 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_29 PF13551.6 ABK75212.1 - 0.00041 20.3 0.3 0.002 18.1 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn helix PaaX PF07848.12 ABK75212.1 - 0.002 18.3 0.1 0.0048 17.1 0.1 1.6 1 0 0 1 1 1 1 PaaX-like protein MarR_2 PF12802.7 ABK75212.1 - 0.0024 17.7 0.1 0.0061 16.4 0.1 1.7 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 ABK75212.1 - 0.0048 16.7 0.1 0.016 15.0 0.1 1.8 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_47 PF16221.5 ABK75212.1 - 0.015 14.8 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 winged helix-turn-helix TrmB PF01978.19 ABK75212.1 - 0.06 13.2 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DnaG_DnaB_bind PF08278.11 ABK75212.1 - 0.071 13.7 1.9 0.42 11.2 0.1 2.3 2 1 0 2 2 2 0 DNA primase DnaG DnaB-binding RPA_C PF08784.11 ABK75212.1 - 0.072 13.8 0.0 0.13 12.9 0.0 1.4 1 0 0 1 1 1 0 Replication protein A C terminal DUF742 PF05331.11 ABK75212.1 - 0.095 12.5 2.2 0.89 9.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF742) ArsP_1 PF03773.13 ABK75213.1 - 1.9e-37 129.1 23.8 6e-21 74.9 18.4 2.6 2 1 0 2 2 2 2 Predicted permease ACP_syn_III PF08545.10 ABK75213.1 - 5.9 6.8 9.7 2.8 7.9 0.2 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GGDEF PF00990.21 ABK75214.1 - 2.1e-10 40.6 0.0 3.7e-10 39.8 0.0 1.4 1 1 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Phage_holin_5_2 PF16079.5 ABK75214.1 - 0.76 10.2 8.1 0.82 10.0 1.1 2.7 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V MerR_1 PF13411.6 ABK75215.1 - 2.4e-12 46.7 0.0 4.2e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 ABK75215.1 - 1.4e-08 34.4 0.0 2.6e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 MerR family regulatory protein GyrI-like PF06445.15 ABK75215.1 - 4.2e-06 27.1 0.0 6e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 GyrI-like small molecule binding domain MerR-DNA-bind PF09278.11 ABK75215.1 - 8.6e-06 26.2 3.0 1.5e-05 25.4 3.0 1.4 1 0 0 1 1 1 1 MerR, DNA binding MerR_2 PF13591.6 ABK75215.1 - 0.03 14.2 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 MerR HTH family regulatory protein ATP-grasp_4 PF13535.6 ABK75215.1 - 0.13 11.8 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain DUF4235 PF14019.6 ABK75216.1 - 9.7e-23 80.0 0.1 1.1e-22 79.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4235) Abhydrolase_9_N PF15420.6 ABK75216.1 - 0.0052 16.8 0.0 0.0058 16.7 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta-hydrolase family N-terminus WES_acyltransf PF03007.16 ABK75217.1 - 2.2e-67 227.6 0.3 3.5e-67 227.0 0.3 1.2 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 ABK75217.1 - 2.8e-12 46.8 0.0 4.4e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) Chorismate_bind PF00425.18 ABK75218.1 - 1.6e-68 231.1 0.0 2e-68 230.8 0.0 1.1 1 0 0 1 1 1 1 chorismate binding enzyme HTH_20 PF12840.7 ABK75219.1 - 3.4e-07 30.2 0.1 9.9e-07 28.7 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 ABK75219.1 - 0.00012 21.8 1.7 0.00039 20.2 0.1 2.5 3 1 0 3 3 3 1 IclR helix-turn-helix domain HTH_5 PF01022.20 ABK75219.1 - 0.00015 21.5 0.0 0.00045 20.0 0.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family LexA_DNA_bind PF01726.16 ABK75219.1 - 0.00048 19.8 0.0 0.0014 18.4 0.0 1.8 1 0 0 1 1 1 1 LexA DNA binding domain HTH_11 PF08279.12 ABK75219.1 - 0.0005 20.0 0.0 0.00098 19.0 0.0 1.5 1 0 0 1 1 1 1 HTH domain MarR_2 PF12802.7 ABK75219.1 - 0.0018 18.1 4.1 0.012 15.5 0.6 2.9 3 0 0 3 3 3 1 MarR family HTH_30 PF13556.6 ABK75219.1 - 0.0052 16.6 0.2 0.021 14.6 0.0 2.1 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 ABK75219.1 - 0.0067 15.8 0.1 0.26 10.7 0.0 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain of transposase family ISL3 GerE PF00196.19 ABK75219.1 - 0.015 14.8 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family FaeA PF04703.12 ABK75219.1 - 0.028 14.8 0.0 0.05 14.0 0.0 1.4 1 0 0 1 1 1 0 FaeA-like protein HTH_24 PF13412.6 ABK75219.1 - 0.029 13.9 0.0 0.073 12.6 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DprA_WH PF17782.1 ABK75219.1 - 0.041 14.0 3.5 0.2 11.8 0.4 3.2 3 0 0 3 3 3 0 DprA winged helix domain Rrf2 PF02082.20 ABK75219.1 - 0.041 14.2 0.0 0.083 13.2 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator TrmB PF01978.19 ABK75219.1 - 0.072 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_23 PF13384.6 ABK75219.1 - 0.098 12.5 0.1 0.33 10.8 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain Sigma70_r4_2 PF08281.12 ABK75219.1 - 0.13 11.9 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_10 PF04967.12 ABK75219.1 - 0.19 11.6 0.0 0.58 10.0 0.0 1.8 1 0 0 1 1 1 0 HTH DNA binding domain OTCace PF00185.24 ABK75220.1 - 4.1e-54 182.9 0.0 7e-54 182.2 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 ABK75220.1 - 4.1e-45 153.4 0.0 6.3e-45 152.8 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain adh_short_C2 PF13561.6 ABK75221.1 - 1.5e-54 185.0 7.3 1.8e-54 184.8 7.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK75221.1 - 1.8e-38 132.0 5.0 2.2e-38 131.7 5.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK75221.1 - 4.2e-13 49.6 2.5 1.4e-12 47.9 2.0 1.8 1 1 1 2 2 2 1 KR domain 2-Hacid_dh_C PF02826.19 ABK75221.1 - 0.037 13.4 0.1 0.064 12.6 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 ABK75221.1 - 0.05 13.6 0.2 0.05 13.6 0.2 2.6 3 1 0 3 3 3 0 Zinc-binding dehydrogenase NmrA PF05368.13 ABK75221.1 - 0.19 11.3 2.3 0.3 10.6 2.3 1.3 1 0 0 1 1 1 0 NmrA-like family ELFV_dehydrog PF00208.21 ABK75221.1 - 0.48 10.1 3.5 0.16 11.6 0.5 1.7 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 3HCDH_N PF02737.18 ABK75221.1 - 0.87 9.4 3.6 0.35 10.7 0.8 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain BPD_transp_2 PF02653.16 ABK75223.1 - 5.7e-43 147.0 45.9 5.7e-43 147.0 45.9 1.3 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component adh_short_C2 PF13561.6 ABK75224.1 - 1.4e-52 178.6 6.6 1.7e-52 178.3 6.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK75224.1 - 4.8e-44 150.2 1.7 5.6e-44 149.9 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK75224.1 - 3.8e-07 30.2 2.4 4.5e-07 30.0 2.0 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK75224.1 - 0.00028 20.5 0.3 0.00042 19.9 0.3 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 ABK75224.1 - 0.015 15.3 4.7 1.1 9.2 0.2 2.5 1 1 0 2 2 2 0 Zinc-binding dehydrogenase DFP PF04127.15 ABK75224.1 - 0.09 12.6 3.6 0.31 10.8 3.4 1.8 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Whib PF02467.16 ABK75225.1 - 1.4e-06 28.8 1.8 1.9e-06 28.4 1.8 1.2 1 0 0 1 1 1 1 Transcription factor WhiB Acyl_transf_3 PF01757.22 ABK75228.1 - 6.4e-23 81.3 38.3 7.9e-23 81.1 38.3 1.1 1 0 0 1 1 1 1 Acyltransferase family ABC_tran PF00005.27 ABK75230.1 - 1.5e-29 103.3 0.0 3e-29 102.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter OB_MalK PF17912.1 ABK75230.1 - 1.3e-12 48.3 0.1 2e-11 44.5 0.1 2.8 2 0 0 2 2 2 1 MalK OB fold domain TOBE PF03459.17 ABK75230.1 - 8.5e-05 22.8 0.8 0.012 15.9 0.2 3.3 2 1 0 2 2 2 1 TOBE domain RsgA_GTPase PF03193.16 ABK75230.1 - 0.00018 21.5 0.1 0.00054 19.9 0.1 1.8 2 0 0 2 2 2 1 RsgA GTPase TOBE_2 PF08402.10 ABK75230.1 - 0.00032 20.8 0.6 0.41 10.8 0.1 3.4 2 1 1 3 3 3 1 TOBE domain SMC_N PF02463.19 ABK75230.1 - 0.0025 17.3 0.1 0.028 13.9 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ABK75230.1 - 0.0029 18.0 0.6 0.0063 16.9 0.1 1.9 2 1 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 ABK75230.1 - 0.0032 17.4 0.0 0.005 16.8 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 ABK75230.1 - 0.0036 17.6 0.1 0.0078 16.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 ABK75230.1 - 0.0047 16.8 0.0 0.35 10.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AIG1 PF04548.16 ABK75230.1 - 0.0076 15.6 0.1 0.02 14.2 0.1 1.7 2 0 0 2 2 2 1 AIG1 family AAA_25 PF13481.6 ABK75230.1 - 0.015 14.9 0.1 0.088 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain CysA_C_terminal PF17850.1 ABK75230.1 - 0.018 15.6 0.0 1.8 9.2 0.0 3.6 3 0 0 3 3 3 0 CysA C-terminal regulatory domain AAA_29 PF13555.6 ABK75230.1 - 0.027 14.2 0.1 0.065 13.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 ABK75230.1 - 0.068 13.7 0.0 0.18 12.4 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA PF00004.29 ABK75230.1 - 0.068 13.6 0.0 0.19 12.1 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 ABK75230.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 ABK75230.1 - 0.13 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 ABK75230.1 - 0.14 12.5 0.0 0.35 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 ABK75230.1 - 0.15 11.4 0.0 0.33 10.2 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.6 ABK75230.1 - 0.21 12.1 0.2 0.4 11.2 0.2 1.4 1 0 0 1 1 1 0 AAA domain DUF3093 PF11292.8 ABK75231.1 - 7.8e-52 175.3 11.3 8.8e-52 175.1 11.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3093) DctQ PF04290.12 ABK75231.1 - 4.9 7.1 11.0 25 4.8 1.5 2.1 1 1 1 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component HTH_32 PF13565.6 ABK75232.1 - 0.011 16.4 0.0 0.032 14.8 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain EcsC PF12787.7 ABK75232.1 - 0.013 15.2 0.7 0.038 13.6 0.7 1.9 1 1 0 1 1 1 0 EcsC protein family IL31 PF15209.6 ABK75232.1 - 0.22 11.3 0.0 0.35 10.6 0.0 1.2 1 0 0 1 1 1 0 Interleukin 31 adh_short PF00106.25 ABK75233.1 - 1.8e-40 138.5 0.0 2.4e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK75233.1 - 1.4e-30 106.6 0.1 1.8e-30 106.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 ABK75233.1 - 9.3e-12 45.2 0.3 1.3e-11 44.7 0.3 1.3 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 ABK75233.1 - 1.1e-08 35.2 0.0 1.6e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK75233.1 - 1e-05 25.1 0.0 2.3e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ABK75233.1 - 0.0002 20.6 0.1 0.00033 19.9 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 ABK75233.1 - 0.0037 16.7 0.0 0.0075 15.7 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase DUF1776 PF08643.10 ABK75233.1 - 0.0063 15.9 0.0 0.0084 15.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_4 PF07993.12 ABK75233.1 - 0.038 13.1 0.6 0.23 10.6 0.5 2.2 1 1 0 1 1 1 0 Male sterility protein NmrA PF05368.13 ABK75233.1 - 0.089 12.3 0.0 0.31 10.5 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family PknH_C PF14032.6 ABK75234.1 - 4.8e-40 137.4 0.2 5.2e-40 137.3 0.2 1.0 1 0 0 1 1 1 1 PknH-like extracellular domain PspA_IM30 PF04012.12 ABK75235.1 - 0.0003 20.5 0.6 0.00034 20.3 0.6 1.0 1 0 0 1 1 1 1 PspA/IM30 family HEM4 PF02602.15 ABK75236.1 - 1.9e-65 220.5 0.1 1.5e-64 217.5 0.1 2.1 2 0 0 2 2 2 1 Uroporphyrinogen-III synthase HemD TP_methylase PF00590.20 ABK75236.1 - 1.1e-38 133.3 4.9 3.4e-38 131.7 4.9 1.9 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TROVE PF05731.11 ABK75237.1 - 8.1e-59 199.8 0.0 1.2e-54 186.1 0.0 2.2 1 1 1 2 2 2 2 TROVE domain DUF5308 PF17233.2 ABK75237.1 - 0.67 10.2 3.6 0.24 11.6 0.5 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5308) MHB PF16525.5 ABK75238.1 - 1.3e-28 99.0 0.1 1.8e-28 98.6 0.1 1.2 1 0 0 1 1 1 1 Haemophore, haem-binding DUF726 PF05277.12 ABK75238.1 - 2.9 6.7 6.2 3.4 6.5 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) PIG-L PF02585.17 ABK75239.1 - 1.8e-08 35.1 0.1 7.6e-08 33.0 0.1 1.9 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase Ribosomal_L25p PF01386.19 ABK75240.1 - 1.8e-24 86.1 0.2 3.5e-24 85.1 0.1 1.5 2 0 0 2 2 2 1 Ribosomal L25p family Ribosomal_TL5_C PF14693.6 ABK75240.1 - 1.7e-18 66.7 2.6 3.3e-17 62.6 4.7 1.9 2 0 0 2 2 2 1 Ribosomal protein TL5, C-terminal domain SnoaL_2 PF12680.7 ABK75241.1 - 1.9e-09 38.1 0.9 2.4e-09 37.8 0.9 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 ABK75241.1 - 0.0043 16.9 0.1 0.0065 16.3 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase ABC2_membrane_4 PF12730.7 ABK75242.1 - 0.0008 19.4 8.3 0.0017 18.4 8.3 1.5 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 ABK75242.1 - 0.001 18.3 17.0 0.0015 17.7 17.0 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 ABK75242.1 - 9.4 5.4 18.7 3.3 6.9 15.6 1.9 2 1 0 2 2 2 0 ABC-2 family transporter protein PepSY_TM PF03929.16 ABK75243.1 - 2.1e-64 218.0 15.5 3.1e-64 217.4 15.5 1.2 1 0 0 1 1 1 1 PepSY-associated TM region PepSY PF03413.19 ABK75243.1 - 4.2e-07 30.4 0.0 0.0001 22.8 0.0 2.6 2 0 0 2 2 2 1 Peptidase propeptide and YPEB domain PepSY_TM_like_2 PF16357.5 ABK75243.1 - 3.5e-05 23.9 3.7 0.0022 18.0 0.0 3.2 3 0 0 3 3 3 1 Putative PepSY_TM-like DUF2231 PF09990.9 ABK75243.1 - 0.015 15.7 2.3 0.015 15.7 2.3 3.8 3 1 1 4 4 4 0 Predicted membrane protein (DUF2231) Nucleos_tra2_N PF01773.20 ABK75243.1 - 0.055 14.1 0.1 0.055 14.1 0.1 2.6 3 0 0 3 3 3 0 Na+ dependent nucleoside transporter N-terminus Cytochrom_B561 PF03188.16 ABK75243.1 - 0.22 11.7 8.1 0.69 10.0 0.1 3.0 4 0 0 4 4 4 0 Eukaryotic cytochrome b561 RskA PF10099.9 ABK75243.1 - 0.83 9.9 19.8 1.6 9.0 0.4 3.5 2 1 1 3 3 3 0 Anti-sigma-K factor rskA Shikimate_dh_N PF08501.11 ABK75245.1 - 2.3e-20 72.6 0.0 4.8e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 ABK75245.1 - 1.5e-12 47.0 0.2 3.7e-12 45.8 0.2 1.7 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 ABK75245.1 - 6e-05 23.1 0.1 0.0001 22.4 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 ABK75245.1 - 0.028 15.0 0.5 0.054 14.1 0.5 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 ABK75245.1 - 0.066 13.5 0.3 0.1 12.8 0.3 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ThiF PF00899.21 ABK75245.1 - 0.3 10.4 2.0 0.64 9.3 2.0 1.5 1 0 0 1 1 1 0 ThiF family p450 PF00067.22 ABK75246.1 - 2.4e-29 102.4 0.1 3.7e-20 72.1 0.1 3.1 1 1 2 3 3 3 3 Cytochrome P450 adh_short PF00106.25 ABK75247.1 - 2.6e-49 167.4 0.1 3.4e-49 166.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK75247.1 - 2.3e-37 128.8 1.2 2.6e-37 128.6 1.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK75247.1 - 2.7e-14 53.5 0.2 4.2e-14 52.9 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK75247.1 - 3.4e-05 23.4 0.1 5e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PALP PF00291.25 ABK75247.1 - 0.00077 19.0 4.8 0.015 14.7 0.7 2.8 2 1 0 3 3 3 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 ABK75247.1 - 0.013 15.4 0.7 0.028 14.4 0.7 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF1776 PF08643.10 ABK75247.1 - 0.21 10.9 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Glyoxalase PF00903.25 ABK75249.1 - 1.1e-11 45.0 0.2 1.4e-11 44.6 0.2 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ABK75249.1 - 0.027 14.7 0.1 0.034 14.4 0.1 1.1 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TetR_N PF00440.23 ABK75250.1 - 0.00046 19.9 0.0 0.0012 18.6 0.0 1.8 1 1 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_15 PF17918.1 ABK75250.1 - 0.33 11.7 11.3 0.061 14.1 2.4 2.8 2 2 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain SLAC1 PF03595.17 ABK75251.1 - 3.6e-67 226.9 53.6 4.2e-67 226.7 53.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Acyl_transf_1 PF00698.21 ABK75252.1 - 5.1e-96 321.9 3.6 7.9e-96 321.3 3.6 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.26 ABK75252.1 - 2.9e-91 305.5 0.3 6.5e-91 304.4 0.3 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 ABK75252.1 - 2.1e-56 190.7 0.4 2.1e-56 190.7 0.4 3.4 3 0 0 3 3 3 1 KR domain PS-DH PF14765.6 ABK75252.1 - 5.4e-51 173.6 4.6 1.3e-50 172.4 4.6 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 ABK75252.1 - 6.8e-40 135.8 0.6 1.8e-39 134.4 0.6 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.26 ABK75252.1 - 1.6e-22 79.9 0.3 1.7e-20 73.4 0.1 3.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ABK75252.1 - 1.3e-20 74.8 0.0 7.7e-20 72.3 0.0 2.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 ABK75252.1 - 4e-10 40.1 0.0 1.1e-09 38.7 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 ABK75252.1 - 3.2e-09 37.0 0.1 8.1e-09 35.7 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 ABK75252.1 - 1.3e-08 34.6 0.7 2.5e-07 30.4 0.0 3.1 3 0 0 3 3 3 1 short chain dehydrogenase Thiolase_N PF00108.23 ABK75252.1 - 3.8e-06 26.4 0.6 3.8e-06 26.4 0.6 2.5 3 0 0 3 3 3 1 Thiolase, N-terminal domain ADH_N PF08240.12 ABK75252.1 - 6.6e-06 26.0 0.1 2e-05 24.4 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain RmlD_sub_bind PF04321.17 ABK75252.1 - 0.036 13.2 0.5 0.1 11.7 0.1 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain TM1506 PF08973.10 ABK75252.1 - 0.18 11.5 0.0 0.39 10.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1893) UDG PF03167.19 ABK75253.1 - 1.1e-26 93.7 0.0 1.5e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Putative_PNPOx PF01243.20 ABK75254.1 - 2.4e-17 62.9 0.0 9.1e-17 61.0 0.0 2.0 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase adh_short PF00106.25 ABK75254.1 - 2.6e-13 49.9 0.1 6.8e-13 48.5 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase Pyridox_ox_2 PF12900.7 ABK75254.1 - 7.4e-08 32.5 0.2 2.1e-07 31.1 0.2 1.8 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase adh_short_C2 PF13561.6 ABK75254.1 - 2e-06 27.5 0.3 7.2e-06 25.7 0.1 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK75254.1 - 2.9e-06 27.3 0.7 6.3e-06 26.2 0.7 1.6 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK75254.1 - 0.016 14.7 0.1 0.03 13.8 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pyrid_ox_like PF16242.5 ABK75254.1 - 0.053 13.1 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like TIM PF00121.18 ABK75255.1 - 1.1e-62 211.6 0.0 1.3e-62 211.3 0.0 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase PEP-utilizers_C PF02896.18 ABK75256.1 - 3.5e-79 266.0 0.0 5.7e-79 265.3 0.0 1.3 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.23 ABK75256.1 - 7.4e-21 73.7 0.7 2.9e-20 71.8 0.7 2.0 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain PEP-utilisers_N PF05524.13 ABK75256.1 - 2.3e-19 69.7 2.9 4.5e-19 68.7 1.7 2.2 2 0 0 2 2 2 1 PEP-utilising enzyme, N-terminal HxlR PF01638.17 ABK75257.1 - 1.2e-28 98.7 0.2 1.5e-28 98.4 0.2 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix MarR PF01047.22 ABK75257.1 - 0.00011 22.0 0.1 0.00019 21.3 0.1 1.4 1 0 0 1 1 1 1 MarR family PadR PF03551.14 ABK75257.1 - 0.0011 18.8 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_20 PF12840.7 ABK75257.1 - 0.0079 16.2 0.1 0.012 15.6 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Replic_Relax PF13814.6 ABK75257.1 - 0.041 13.9 0.1 0.055 13.5 0.1 1.2 1 0 0 1 1 1 0 Replication-relaxation HTH_12 PF08461.10 ABK75257.1 - 0.11 12.5 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain ABC_tran PF00005.27 ABK75258.1 - 6.1e-33 114.2 0.0 1.2e-32 113.2 0.0 1.5 2 0 0 2 2 2 1 ABC transporter BCA_ABC_TP_C PF12399.8 ABK75258.1 - 4.5e-10 39.2 0.1 9.2e-10 38.2 0.1 1.6 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_21 PF13304.6 ABK75258.1 - 1.2e-07 31.9 0.7 0.0075 16.1 0.2 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ABK75258.1 - 0.00075 20.0 0.1 0.0011 19.5 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ABK75258.1 - 0.00083 19.0 0.0 0.0019 17.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ABK75258.1 - 0.045 13.8 0.1 0.18 11.9 0.1 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_15 PF13175.6 ABK75258.1 - 0.054 13.2 0.0 2.2 7.9 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 ABK75258.1 - 0.057 13.1 0.1 0.17 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 ABK75258.1 - 0.099 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 ABK75258.1 - 0.12 11.8 0.1 0.47 9.9 0.1 1.7 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ABK75258.1 - 0.14 12.4 0.4 0.68 10.2 0.4 2.1 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 ABK75258.1 - 0.16 12.4 0.1 0.38 11.2 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TPP_enzyme_C PF02775.21 ABK75259.1 - 4.1e-30 104.6 0.0 6.7e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PFO_beta_C PF12367.8 ABK75259.1 - 0.046 13.8 0.0 0.37 10.9 0.0 2.2 2 0 0 2 2 2 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal Abhydrolase_1 PF00561.20 ABK75261.1 - 1.4e-11 44.5 0.0 2.4e-09 37.2 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Guanylate_cyc PF00211.20 ABK75261.1 - 5.9e-07 29.3 0.0 7.3e-06 25.7 0.0 2.2 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Abhydrolase_4 PF08386.10 ABK75261.1 - 4.9e-05 23.4 0.0 0.00061 19.9 0.0 2.2 2 0 0 2 2 2 1 TAP-like protein Hydrolase_4 PF12146.8 ABK75261.1 - 0.00015 21.1 0.0 0.4 9.9 0.0 2.5 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DUF2826 PF11442.8 ABK75261.1 - 0.0061 16.4 0.1 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2826) Sigma70_r2 PF04542.14 ABK75263.1 - 3.7e-20 71.4 0.6 7.5e-20 70.5 0.6 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 ABK75263.1 - 2.2e-12 46.5 2.1 2.3e-12 46.4 0.4 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 SnoaL_2 PF12680.7 ABK75263.1 - 7.7e-10 39.3 0.4 2.4e-09 37.8 0.1 2.0 2 0 0 2 2 2 1 SnoaL-like domain Sigma70_r4 PF04545.16 ABK75263.1 - 1.3e-07 31.1 0.4 2.3e-07 30.2 0.4 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 NTF2 PF02136.20 ABK75263.1 - 9.5e-05 22.9 0.0 0.00035 21.1 0.0 1.9 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain SnoaL_4 PF13577.6 ABK75263.1 - 0.00066 19.8 0.1 0.0016 18.5 0.0 1.7 2 0 0 2 2 2 1 SnoaL-like domain SnoaL_3 PF13474.6 ABK75263.1 - 0.011 16.0 0.2 0.027 14.8 0.0 1.9 2 0 0 2 2 2 0 SnoaL-like domain DUF4440 PF14534.6 ABK75263.1 - 0.12 12.8 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) OB_aCoA_assoc PF01796.17 ABK75264.1 - 5.5e-13 48.7 0.8 8.3e-13 48.1 0.8 1.3 1 0 0 1 1 1 1 DUF35 OB-fold domain, acyl-CoA-associated DUF35_N PF12172.8 ABK75264.1 - 3.1e-09 36.5 1.9 6.5e-09 35.5 1.9 1.6 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) TackOD1 PF18551.1 ABK75264.1 - 0.002 17.8 0.7 0.0028 17.4 0.7 1.1 1 0 0 1 1 1 1 Thaumarchaeal output domain 1 zf-FPG_IleRS PF06827.14 ABK75264.1 - 0.014 15.2 0.5 5.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zinc_ribbon_15 PF17032.5 ABK75264.1 - 0.071 13.9 0.2 0.098 13.4 0.2 1.3 1 0 0 1 1 1 0 zinc-ribbon family HypA PF01155.19 ABK75264.1 - 0.2 11.7 0.5 0.36 10.9 0.5 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_Tnp_IS1 PF03811.13 ABK75264.1 - 6.3 6.6 7.7 0.14 11.9 1.4 1.5 2 0 0 2 2 2 0 InsA N-terminal domain ECH_1 PF00378.20 ABK75265.1 - 8.9e-38 130.0 0.1 3.8e-24 85.4 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK75265.1 - 1e-09 38.3 0.1 1.3e-08 34.8 0.1 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF4395 PF14340.6 ABK75266.1 - 1.2e-45 155.1 15.1 1.3e-45 154.9 15.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4395) Cg6151-P PF10233.9 ABK75266.1 - 0.0036 17.6 4.3 0.47 10.8 0.1 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein CG6151-P PRA1 PF03208.19 ABK75266.1 - 1.2 8.8 5.9 1.6 8.3 5.9 1.2 1 0 0 1 1 1 0 PRA1 family protein PTS_EIIC_2 PF13303.6 ABK75266.1 - 4.4 6.2 18.0 0.098 11.7 3.0 2.1 2 0 0 2 2 2 0 Phosphotransferase system, EIIC DUF3040 PF11239.8 ABK75266.1 - 9.5 6.6 14.0 2.5 8.4 3.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) AraC_binding PF02311.19 ABK75267.1 - 9.3e-19 67.7 0.2 1.9e-18 66.7 0.1 1.6 2 0 0 2 2 2 1 AraC-like ligand binding domain HTH_18 PF12833.7 ABK75267.1 - 1e-17 64.1 1.5 1e-17 64.1 1.5 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 ABK75267.1 - 1.4e-12 47.4 0.0 1.6e-07 31.2 0.0 2.5 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family NUDIX PF00293.28 ABK75268.1 - 1.7e-09 37.8 0.6 2.2e-09 37.4 0.6 1.2 1 0 0 1 1 1 1 NUDIX domain AIM24 PF01987.17 ABK75269.1 - 4.6e-33 114.7 0.7 5.5e-33 114.5 0.7 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF2510 PF10708.9 ABK75269.1 - 2.1e-07 30.5 10.5 2.1e-07 30.5 10.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2510) CPSase_L_D2 PF02786.17 ABK75270.1 - 1.4e-67 227.3 0.2 2.1e-67 226.7 0.2 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 ABK75270.1 - 2.1e-56 190.8 0.0 8.4e-56 188.9 0.0 2.0 3 0 0 3 3 3 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 ABK75270.1 - 2.3e-41 140.8 0.1 6.2e-41 139.4 0.1 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ABK75270.1 - 7.7e-37 125.7 0.0 1.9e-36 124.5 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 ABK75270.1 - 1.5e-26 93.5 0.0 3.6e-26 92.3 0.0 1.7 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 ABK75270.1 - 4.9e-15 55.1 1.7 1.3e-14 53.7 1.7 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 ABK75270.1 - 4.6e-10 39.4 0.0 9e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 ABK75270.1 - 5.7e-07 29.3 2.4 0.00065 19.5 0.1 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 ABK75270.1 - 5.8e-05 23.2 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.6 ABK75270.1 - 0.00016 21.6 1.0 0.00043 20.2 1.0 1.8 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 ABK75270.1 - 0.03 14.2 0.4 0.063 13.2 0.4 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein Peptidase_M23 PF01551.22 ABK75270.1 - 0.038 14.2 0.7 2.9 8.2 0.3 3.2 2 1 1 3 3 3 0 Peptidase family M23 AstE_AspA PF04952.14 ABK75270.1 - 0.059 12.4 0.2 0.19 10.8 0.2 1.9 2 0 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family NQRA PF05896.11 ABK75270.1 - 0.072 12.5 0.2 0.13 11.7 0.2 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) HlyD_3 PF13437.6 ABK75270.1 - 0.17 12.6 2.5 0.35 11.6 1.4 2.2 2 0 0 2 2 1 0 HlyD family secretion protein HlyD_D23 PF16576.5 ABK75270.1 - 0.38 9.9 2.1 0.86 8.8 0.1 2.2 2 1 1 3 3 3 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion DUF2236 PF09995.9 ABK75271.1 - 6.1e-44 150.9 7.3 8.4e-44 150.5 7.3 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) BPD_transp_1 PF00528.22 ABK75272.1 - 3.3e-16 59.6 8.1 3.3e-16 59.6 8.1 1.4 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component CN_hydrolase PF00795.22 ABK75274.1 - 2.9e-63 213.7 0.0 3.3e-63 213.5 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Acyltransferase PF01553.21 ABK75275.1 - 5.6e-30 103.7 0.0 7.3e-30 103.3 0.0 1.1 1 0 0 1 1 1 1 Acyltransferase Lip_A_acyltrans PF03279.13 ABK75275.1 - 0.014 14.6 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial lipid A biosynthesis acyltransferase BPD_transp_1 PF00528.22 ABK75276.1 - 8.1e-18 64.8 11.7 8.1e-18 64.8 11.7 2.1 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Yip1 PF04893.17 ABK75276.1 - 0.024 14.4 22.6 0.056 13.2 15.1 2.3 2 0 0 2 2 2 0 Yip1 domain CTC1_2 PF15491.6 ABK75276.1 - 0.098 11.9 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 Mur_ligase_M PF08245.12 ABK75277.1 - 1.7e-40 139.1 0.0 3.6e-40 138.0 0.0 1.5 2 0 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.21 ABK75277.1 - 6.6e-25 87.2 0.4 3.9e-24 84.7 0.1 2.4 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Mur_ligase PF01225.25 ABK75277.1 - 5.7e-10 39.4 0.7 2.8e-09 37.2 0.7 2.2 1 0 0 1 1 1 1 Mur ligase family, catalytic domain PG_isomerase_N PF18353.1 ABK75277.1 - 0.016 15.6 2.2 1.4 9.3 0.1 3.4 1 1 2 3 3 3 0 Phosphoglucose isomerase N-terminal domain ADH_N PF08240.12 ABK75278.1 - 1.2e-27 95.9 2.5 1.2e-27 95.9 2.5 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ABK75278.1 - 1.5e-27 96.1 0.6 2.8e-27 95.2 0.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ABK75278.1 - 3.7e-09 37.7 0.2 7.6e-09 36.7 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ABK75278.1 - 1e-05 25.1 1.6 2e-05 24.2 1.6 1.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus TrkA_N PF02254.18 ABK75278.1 - 0.0043 17.3 0.9 0.0079 16.4 0.8 1.5 1 1 0 1 1 1 1 TrkA-N domain Methyltransf_25 PF13649.6 ABK75278.1 - 0.04 14.6 0.3 0.082 13.6 0.3 1.5 1 0 0 1 1 1 0 Methyltransferase domain Prot_ATP_ID_OB PF16450.5 ABK75278.1 - 0.14 12.2 1.4 67 3.5 0.0 3.5 3 0 0 3 3 3 0 Proteasomal ATPase OB C-terminal domain SBP_bac_3 PF00497.20 ABK75279.1 - 1.3e-46 158.8 0.0 1.5e-46 158.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 ABK75279.1 - 0.00091 19.4 0.0 0.013 15.6 0.0 2.4 2 1 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site DUF2016 PF09436.10 ABK75279.1 - 0.11 12.4 0.0 3 7.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2016) Cupin_2 PF07883.11 ABK75281.1 - 1.8e-09 37.2 0.2 2.9e-09 36.5 0.2 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 ABK75281.1 - 0.00041 20.2 0.0 0.00056 19.8 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain MurB_C PF02873.16 ABK75282.1 - 2.7e-35 121.0 0.0 4.8e-35 120.2 0.0 1.4 1 0 0 1 1 1 1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain FAD_binding_4 PF01565.23 ABK75282.1 - 1.1e-21 77.0 1.1 2.1e-21 76.1 1.1 1.5 1 0 0 1 1 1 1 FAD binding domain ABC_tran PF00005.27 ABK75283.1 - 1.2e-49 168.4 0.1 1.2e-24 87.4 0.1 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ABK75283.1 - 1.2e-11 45.0 10.0 0.011 15.5 0.0 4.7 4 1 0 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_CTD PF16326.5 ABK75283.1 - 1.5e-07 31.6 5.2 1.5e-07 31.6 5.2 1.9 2 0 0 2 2 1 1 ABC transporter C-terminal domain SMC_N PF02463.19 ABK75283.1 - 2.5e-07 30.4 2.3 0.016 14.7 0.3 4.1 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain ABC_tran_Xtn PF12848.7 ABK75283.1 - 3.2e-07 30.3 0.0 4.8e-06 26.5 0.0 2.5 3 0 0 3 3 3 1 ABC transporter AAA_29 PF13555.6 ABK75283.1 - 6.8e-07 28.9 1.5 0.007 16.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 ABK75283.1 - 7.8e-07 29.8 1.2 0.0019 18.7 0.1 2.8 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 ABK75283.1 - 4.2e-05 23.6 2.0 0.11 12.6 0.2 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ABK75283.1 - 0.00023 21.1 0.5 0.13 12.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 ABK75283.1 - 0.00077 19.6 0.6 1.7 8.6 0.0 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain MeaB PF03308.16 ABK75283.1 - 0.021 13.8 5.3 0.49 9.3 0.2 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP-synt_ab PF00006.25 ABK75283.1 - 0.024 14.3 0.3 4.3 6.9 0.0 2.8 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain SOGA PF11365.8 ABK75283.1 - 0.06 14.5 1.3 0.43 11.7 0.8 2.3 2 0 0 2 2 2 0 Protein SOGA Ploopntkinase3 PF18751.1 ABK75283.1 - 0.068 13.1 0.3 5 7.0 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_16 PF13191.6 ABK75283.1 - 0.08 13.3 5.0 0.16 12.4 0.1 2.9 3 0 0 3 3 2 0 AAA ATPase domain RNA_helicase PF00910.22 ABK75283.1 - 0.11 12.9 0.3 4.7 7.6 0.0 2.3 2 0 0 2 2 2 0 RNA helicase GTP_EFTU PF00009.27 ABK75283.1 - 0.17 11.4 0.3 7.9 6.0 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 ABK75283.1 - 0.19 11.8 0.3 14 5.7 0.1 2.3 2 0 0 2 2 2 0 Dynamin family Spc7 PF08317.11 ABK75283.1 - 0.21 10.4 1.2 0.34 9.8 1.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_13 PF13166.6 ABK75283.1 - 0.21 10.2 2.9 9 4.8 0.1 3.3 4 0 0 4 4 4 0 AAA domain TMF_DNA_bd PF12329.8 ABK75283.1 - 0.72 9.9 3.3 1.9 8.5 1.8 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding NACHT PF05729.12 ABK75283.1 - 1.8 8.5 4.1 23 4.9 0.6 2.7 2 0 0 2 2 2 0 NACHT domain DUF3584 PF12128.8 ABK75283.1 - 2 5.8 9.6 0.41 8.1 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) AAA_30 PF13604.6 ABK75283.1 - 7.2 6.3 10.6 0.92 9.2 0.0 2.9 4 0 0 4 4 2 0 AAA domain DUF4265 PF14085.6 ABK75284.1 - 2.3e-26 92.0 0.0 2.8e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4265) Transketolase_N PF00456.21 ABK75285.1 - 9.3e-144 478.5 0.0 1.2e-143 478.1 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 ABK75285.1 - 7.2e-43 146.3 0.0 3.9e-42 143.9 0.0 2.1 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ABK75285.1 - 1.4e-13 50.8 0.0 2.8e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 ABK75285.1 - 0.00055 19.2 0.0 0.00098 18.4 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase DUF498 PF04430.14 ABK75285.1 - 0.12 12.4 0.0 0.34 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) adh_short_C2 PF13561.6 ABK75286.1 - 2.9e-50 171.0 2.7 3.6e-50 170.7 2.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK75286.1 - 3.7e-37 127.7 1.1 4.4e-37 127.5 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK75286.1 - 9.2e-07 28.9 0.1 1.9e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 ABK75286.1 - 0.014 15.6 0.1 0.021 15.1 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain THF_DHG_CYH_C PF02882.19 ABK75286.1 - 0.068 12.5 1.2 0.39 10.0 0.3 2.5 2 1 1 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GntR PF00392.21 ABK75287.1 - 1.1e-21 76.3 1.5 2.2e-21 75.3 1.5 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family FCD PF07729.12 ABK75287.1 - 2.1e-19 70.2 7.3 2.1e-19 70.2 7.3 1.9 2 0 0 2 2 2 1 FCD domain HTH_5 PF01022.20 ABK75287.1 - 0.00011 22.0 0.1 0.00073 19.4 0.1 2.3 3 0 0 3 3 3 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 ABK75287.1 - 0.00014 21.8 0.5 0.0012 18.8 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 ABK75287.1 - 0.00023 21.0 0.6 0.0026 17.6 0.2 2.3 2 0 0 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 ABK75287.1 - 0.0004 20.3 0.1 0.0011 18.9 0.1 1.7 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Rrf2 PF02082.20 ABK75287.1 - 0.0042 17.4 0.1 0.0076 16.6 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulator HTH_24 PF13412.6 ABK75287.1 - 0.0059 16.1 0.5 0.015 14.9 0.2 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 ABK75287.1 - 0.0077 16.1 0.1 0.022 14.6 0.1 1.8 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 ABK75287.1 - 0.014 15.2 1.3 0.024 14.4 0.2 1.9 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_11 PF08279.12 ABK75287.1 - 0.043 13.7 0.2 0.4 10.7 0.0 2.6 3 0 0 3 3 3 0 HTH domain Acyl_transf_3 PF01757.22 ABK75288.1 - 1.4e-28 99.9 31.7 1.8e-28 99.6 31.7 1.0 1 0 0 1 1 1 1 Acyltransferase family Peptidase_M41 PF01434.18 ABK75289.1 - 2.7e-70 236.1 1.0 3.8e-70 235.6 1.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 ABK75289.1 - 4e-46 156.7 0.0 8.4e-46 155.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ABK75289.1 - 6.6e-11 41.8 0.2 1.8e-10 40.5 0.2 1.8 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 ABK75289.1 - 9.5e-07 29.1 1.0 3.1e-05 24.3 0.7 2.3 2 0 0 2 2 2 1 FtsH Extracellular AAA_5 PF07728.14 ABK75289.1 - 8e-06 25.9 0.0 3.4e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ABK75289.1 - 9.6e-05 22.8 1.6 0.00075 19.9 0.5 2.6 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 ABK75289.1 - 0.00012 21.9 0.0 0.00057 19.7 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 ABK75289.1 - 0.00029 20.1 0.1 0.00054 19.3 0.1 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 ABK75289.1 - 0.0033 17.7 0.1 0.052 13.8 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 ABK75289.1 - 0.008 16.4 0.0 0.021 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 ABK75289.1 - 0.027 14.2 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 ABK75289.1 - 0.028 13.8 0.1 0.049 13.0 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 ABK75289.1 - 0.035 14.1 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 ABK75289.1 - 0.067 12.9 0.0 0.13 11.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ABK75289.1 - 0.096 12.9 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 ABK75289.1 - 0.13 12.4 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.26 ABK75289.1 - 0.16 11.7 0.0 0.47 10.2 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.6 ABK75289.1 - 0.18 12.3 0.0 0.37 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain FAD-oxidase_C PF02913.19 ABK75290.1 - 3.7e-52 177.4 0.0 7.2e-52 176.5 0.0 1.5 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 ABK75290.1 - 6.7e-33 113.4 6.4 1.3e-32 112.5 6.4 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_5 PF00941.21 ABK75290.1 - 0.0014 18.4 0.5 0.0068 16.1 0.6 2.0 2 0 0 2 2 2 1 FAD binding domain in molybdopterin dehydrogenase DraK_HK_N PF18092.1 ABK75290.1 - 0.37 11.3 3.0 2.2 8.8 0.2 2.7 1 1 1 2 2 2 0 DraK Histidine Kinase N-terminal domain TetR_C_20 PF17925.1 ABK75291.1 - 8.9e-40 135.3 0.5 1.7e-39 134.4 0.5 1.5 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK75291.1 - 3.2e-16 58.8 0.2 7.4e-16 57.7 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_7 PF02796.15 ABK75291.1 - 0.013 15.6 0.0 0.034 14.2 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase MaoC_dehydratas PF01575.19 ABK75292.1 - 1.3e-07 31.2 0.0 0.00087 18.9 0.0 2.2 2 0 0 2 2 2 2 MaoC like domain MarR_2 PF12802.7 ABK75293.1 - 1.7e-12 47.0 1.4 5.9e-12 45.3 0.6 2.1 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 ABK75293.1 - 1.8e-10 41.1 0.0 3.5e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR PF01047.22 ABK75293.1 - 1e-08 35.0 0.0 1.6e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 ABK75293.1 - 7.2e-06 25.7 0.1 1.6e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain TrmB PF01978.19 ABK75293.1 - 2.5e-05 24.1 0.0 6.8e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB TBPIP PF07106.13 ABK75293.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain DDE_Tnp_ISL3 PF01610.17 ABK75294.1 - 1.6e-64 217.9 0.0 2.1e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Transposase zf-ISL3 PF14690.6 ABK75294.1 - 1.1e-09 38.8 4.6 1.8e-09 38.1 2.5 2.5 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HTH_Tnp_ISL3 PF13542.6 ABK75294.1 - 2.4e-08 33.2 1.6 7e-08 31.8 1.6 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 Pyr_redox_2 PF07992.14 ABK75295.1 - 2.3e-25 89.4 0.0 3e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ABK75295.1 - 1.6e-08 34.5 4.6 7.7e-08 32.3 1.3 2.6 1 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ABK75295.1 - 1.3e-06 27.8 4.6 1.4e-06 27.7 1.8 2.4 2 2 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 ABK75295.1 - 7.1e-06 25.0 0.1 0.00015 20.6 0.2 2.6 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.6 ABK75295.1 - 4.8e-05 23.5 1.3 0.00012 22.2 0.8 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ABK75295.1 - 0.0001 22.3 1.0 0.1 12.6 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.22 ABK75295.1 - 0.00016 20.9 2.6 0.0011 18.1 1.6 2.6 2 2 2 4 4 4 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 ABK75295.1 - 0.00041 19.8 1.1 0.00061 19.2 1.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ABK75295.1 - 0.00042 19.7 0.0 0.021 14.1 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ABK75295.1 - 0.0023 17.2 0.3 0.031 13.5 0.2 2.1 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 ABK75295.1 - 0.0032 16.6 3.1 0.094 11.7 0.7 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 ABK75295.1 - 0.0046 16.3 0.1 0.0087 15.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 ABK75295.1 - 0.031 14.9 0.6 0.21 12.1 0.3 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ABK75295.1 - 0.16 10.8 0.3 0.5 9.1 0.1 1.8 2 0 0 2 2 2 0 Tryptophan halogenase TPR_2 PF07719.17 ABK75296.1 - 6.2e-05 22.8 0.9 0.0018 18.3 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 ABK75296.1 - 0.0031 17.6 0.1 0.028 14.6 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 ABK75296.1 - 0.0043 17.5 0.3 0.012 16.1 0.3 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 ABK75296.1 - 0.015 15.7 0.2 0.063 13.7 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 ABK75296.1 - 0.061 14.0 0.6 0.061 14.0 0.6 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 ABK75296.1 - 5.2 7.1 6.7 0.72 9.8 1.4 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat F420_oxidored PF03807.17 ABK75297.1 - 0.00017 22.1 1.3 0.14 12.8 0.1 2.3 1 1 1 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.25 ABK75298.1 - 4.4e-46 156.8 0.0 5.5e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK75298.1 - 3.2e-31 108.7 0.0 4.4e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK75298.1 - 1.7e-13 50.9 0.4 2.3e-13 50.4 0.4 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK75298.1 - 8.9e-06 25.3 0.1 1.8e-05 24.4 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ABK75298.1 - 0.0014 17.8 0.0 0.0021 17.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 ABK75298.1 - 0.0059 17.2 0.3 0.011 16.3 0.3 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.6 ABK75298.1 - 0.011 15.6 0.8 0.017 15.0 0.8 1.3 1 0 0 1 1 1 0 NAD(P)H-binding YjeF_N PF03853.15 ABK75298.1 - 0.028 14.3 0.2 0.043 13.7 0.2 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus GDP_Man_Dehyd PF16363.5 ABK75298.1 - 0.052 12.9 0.0 0.36 10.2 0.0 2.1 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 ABK75298.1 - 0.088 11.9 0.2 0.13 11.3 0.2 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain 3HCDH_N PF02737.18 ABK75298.1 - 0.32 10.9 1.2 0.57 10.1 1.0 1.5 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CMD PF02627.20 ABK75299.1 - 3.4e-12 46.2 0.1 5e-12 45.7 0.1 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family DUF485 PF04341.12 ABK75300.1 - 0.0059 16.5 3.0 0.0067 16.3 0.6 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF485 SseC PF04888.12 ABK75300.1 - 0.66 9.5 5.2 1.5 8.3 5.2 1.6 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DUF4064 PF13273.6 ABK75300.1 - 5 7.5 11.5 0.38 11.1 0.7 3.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Rv2175c_C PF18367.1 ABK75301.1 - 3.3e-29 100.8 0.2 7.1e-29 99.7 0.1 1.6 2 0 0 2 2 2 1 Rv2175c C-terminal domain of unknown function HTH_17 PF12728.7 ABK75301.1 - 0.002 18.3 0.0 0.0056 16.8 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain Lipoprotein_9 PF03180.14 ABK75302.1 - 7.8e-63 211.7 0.0 9e-63 211.5 0.0 1.0 1 0 0 1 1 1 1 NLPA lipoprotein VMA21 PF09446.10 ABK75302.1 - 0.0041 17.2 0.1 0.0077 16.3 0.1 1.4 1 0 0 1 1 1 1 VMA21-like domain PQQ_2 PF13360.6 ABK75303.1 - 2.8e-07 30.4 0.2 0.13 11.9 0.0 3.2 2 1 1 3 3 3 2 PQQ-like domain PQQ_3 PF13570.6 ABK75303.1 - 7e-05 23.2 5.3 7.2 7.2 0.7 5.5 6 0 0 6 6 6 2 PQQ-like domain SGL PF08450.12 ABK75303.1 - 0.051 13.2 0.0 21 4.6 0.0 3.6 3 1 1 4 4 4 0 SMP-30/Gluconolactonase/LRE-like region Kelch_3 PF13415.6 ABK75303.1 - 0.13 12.6 0.2 4.3 7.7 0.1 3.0 2 0 0 2 2 2 0 Galactose oxidase, central domain PQQ PF01011.21 ABK75303.1 - 0.15 12.1 3.9 25 5.0 0.4 4.1 4 0 0 4 4 4 0 PQQ enzyme repeat Rubredoxin PF00301.20 ABK75303.1 - 0.18 11.9 0.3 0.43 10.7 0.3 1.5 1 0 0 1 1 1 0 Rubredoxin NHL PF01436.21 ABK75303.1 - 0.35 11.0 2.8 33 4.8 0.0 4.1 4 0 0 4 4 4 0 NHL repeat ABC_tran PF00005.27 ABK75304.1 - 3.9e-25 89.0 0.0 5.8e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK75304.1 - 9.3e-11 42.1 0.0 5.4e-05 23.1 0.0 2.3 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 ABK75304.1 - 0.002 18.8 0.0 0.0034 18.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) AAA_16 PF13191.6 ABK75304.1 - 0.046 14.1 0.0 0.071 13.5 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 ABK75304.1 - 0.054 13.2 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ABK75304.1 - 0.066 13.7 0.0 0.1 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ABK75304.1 - 0.081 12.7 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ABK75304.1 - 0.087 12.7 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase MeaB PF03308.16 ABK75304.1 - 0.11 11.4 0.1 0.19 10.7 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB adh_short_C2 PF13561.6 ABK75305.1 - 8e-29 100.8 3.2 1.2e-14 54.5 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK75305.1 - 3.5e-21 75.5 1.7 6.7e-15 55.1 2.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 ABK75305.1 - 1.8e-09 37.8 1.5 2.5e-09 37.3 1.5 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK75305.1 - 6.3e-08 32.4 0.2 1.2e-07 31.4 0.3 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ABK75305.1 - 2.2e-07 30.6 0.3 3.1e-07 30.1 0.3 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ABK75305.1 - 0.0034 16.4 0.4 0.0044 16.1 0.4 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 ABK75305.1 - 0.057 13.7 0.1 1.6 9.0 0.4 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Methyltransf_25 PF13649.6 ABK75305.1 - 0.11 13.2 0.2 0.32 11.7 0.1 1.8 2 0 0 2 2 2 0 Methyltransferase domain SBP_bac_11 PF13531.6 ABK75306.1 - 1.1e-43 149.6 5.2 1.3e-43 149.4 5.2 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 ABK75306.1 - 1.7e-17 64.4 4.3 1.4e-08 35.1 0.1 2.1 2 0 0 2 2 2 2 Bacterial extracellular solute-binding protein PBP_like PF12727.7 ABK75306.1 - 1.6e-05 24.1 0.7 0.00014 21.0 0.7 2.5 1 1 0 1 1 1 1 PBP superfamily domain OpuAC PF04069.12 ABK75306.1 - 0.00011 21.9 0.2 0.00014 21.5 0.2 1.2 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system PBP_like_2 PF12849.7 ABK75306.1 - 0.00012 21.8 0.3 0.00012 21.8 0.3 1.8 2 0 0 2 2 2 1 PBP superfamily domain SBP_bac_6 PF13343.6 ABK75306.1 - 0.00013 21.5 0.1 0.00043 19.8 0.1 1.9 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 ABK75306.1 - 0.0038 17.1 1.4 3.6 7.3 0.1 2.8 2 1 1 3 3 3 2 Bacterial extracellular solute-binding protein AP_endonuc_2 PF01261.24 ABK75307.1 - 4.8e-25 88.2 0.3 7.1e-25 87.7 0.3 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel TM2 PF05154.16 ABK75308.1 - 6.6e-12 45.6 8.6 8.5e-12 45.2 8.6 1.1 1 0 0 1 1 1 1 TM2 domain MlaD PF02470.20 ABK75309.1 - 8.3e-16 58.1 0.1 1.5e-15 57.3 0.1 1.4 1 0 0 1 1 1 1 MlaD protein Mce4_CUP1 PF11887.8 ABK75309.1 - 0.075 12.5 0.1 0.27 10.7 0.1 1.7 1 1 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative BA14K PF07886.11 ABK75309.1 - 0.1 12.5 0.9 0.24 11.3 0.9 1.5 1 0 0 1 1 1 0 BA14K-like protein GMC_oxred_N PF00732.19 ABK75310.1 - 3.1e-56 190.9 0.0 3.8e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ABK75310.1 - 1.3e-25 90.6 1.0 1.4e-24 87.3 1.0 2.2 1 1 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 ABK75310.1 - 2.5e-05 23.5 0.9 0.0018 17.4 0.2 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 ABK75310.1 - 0.00012 22.2 0.1 0.00037 20.7 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ABK75310.1 - 0.0015 17.8 0.0 0.17 11.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ABK75310.1 - 0.0026 16.5 0.0 1.4 7.5 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 ABK75310.1 - 0.032 14.8 0.0 0.09 13.4 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ABK75310.1 - 0.032 14.2 0.2 0.44 10.5 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding ApbA PF02558.16 ABK75310.1 - 0.04 13.6 0.0 0.093 12.4 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 ABK75310.1 - 0.071 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain GIDA PF01134.22 ABK75310.1 - 0.13 11.4 0.0 0.57 9.2 0.0 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 ABK75310.1 - 0.24 10.6 0.7 0.66 9.2 0.1 2.0 2 0 0 2 2 2 0 Thi4 family Ribosomal_L10 PF00466.20 ABK75311.1 - 8.1e-27 93.3 0.9 1.5e-26 92.5 0.9 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 DUF3182 PF11379.8 ABK75311.1 - 0.00039 19.5 0.1 0.00048 19.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3182) DUF1688 PF07958.11 ABK75311.1 - 0.014 14.1 0.2 0.66 8.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1688) HTH_IclR PF09339.10 ABK75311.1 - 0.16 11.8 1.3 5.2 7.0 0.1 2.6 2 1 1 3 3 3 0 IclR helix-turn-helix domain COesterase PF00135.28 ABK75312.1 - 3e-90 303.6 0.0 9.1e-90 302.0 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ABK75312.1 - 2e-11 44.1 2.6 8.1e-11 42.2 2.6 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ABK75312.1 - 0.0031 17.0 0.1 0.0073 15.8 0.1 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 ABK75312.1 - 0.14 11.0 0.4 1 8.1 0.4 1.9 1 1 0 1 1 1 0 Steryl acetyl hydrolase BPD_transp_2 PF02653.16 ABK75313.1 - 4.8e-39 134.1 40.1 7.3e-39 133.5 40.1 1.3 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component HTH_8 PF02954.19 ABK75314.1 - 7e-11 41.7 0.2 2.2e-10 40.1 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family HTH_30 PF13556.6 ABK75314.1 - 3.9e-05 23.4 0.4 0.00075 19.2 0.0 2.9 3 0 0 3 3 3 1 PucR C-terminal helix-turn-helix domain GAF PF01590.26 ABK75314.1 - 7.7e-05 23.3 0.0 0.00026 21.6 0.0 1.9 1 0 0 1 1 1 1 GAF domain HTH_50 PF18024.1 ABK75314.1 - 0.00046 19.7 0.1 0.0025 17.4 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 ABK75314.1 - 0.00098 18.9 0.0 0.003 17.3 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 ABK75314.1 - 0.0028 17.7 0.0 0.008 16.2 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 ABK75314.1 - 0.01 16.0 0.0 0.039 14.1 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma54_activat PF00158.26 ABK75314.1 - 0.019 14.7 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Phage_AlpA PF05930.12 ABK75314.1 - 0.037 13.9 0.0 0.076 12.8 0.0 1.4 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) HTH_22 PF13309.6 ABK75314.1 - 0.038 14.1 0.1 0.11 12.6 0.1 1.8 1 1 0 1 1 1 0 HTH domain HTH_17 PF12728.7 ABK75314.1 - 0.12 12.6 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.12 ABK75314.1 - 0.14 12.1 0.1 0.5 10.4 0.0 2.0 2 0 0 2 2 1 0 HTH domain Pyr_redox_2 PF07992.14 ABK75315.1 - 3.9e-55 187.2 3.4 5e-55 186.8 3.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ABK75315.1 - 1.5e-22 79.9 0.1 3.1e-22 78.9 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 ABK75315.1 - 1.5e-21 76.8 5.3 2.2e-17 63.4 0.9 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ABK75315.1 - 2.6e-10 40.1 0.8 6.7e-08 32.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ABK75315.1 - 5.2e-08 32.4 5.7 8.1e-07 28.4 0.1 3.3 3 1 1 4 4 4 1 Glucose inhibited division protein A K_oxygenase PF13434.6 ABK75315.1 - 2.6e-06 26.8 0.4 5.4e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 ABK75315.1 - 1.1e-05 25.0 2.8 0.0088 15.4 0.9 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 ABK75315.1 - 7e-05 21.7 1.6 0.15 10.7 0.6 2.6 3 0 0 3 3 3 2 HI0933-like protein Trp_halogenase PF04820.14 ABK75315.1 - 0.0041 16.0 0.3 0.0041 16.0 0.3 2.3 3 0 0 3 3 3 1 Tryptophan halogenase NAD_binding_7 PF13241.6 ABK75315.1 - 0.0051 17.2 1.4 0.22 12.0 0.1 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding XdhC_C PF13478.6 ABK75315.1 - 0.026 15.0 1.6 0.047 14.2 0.1 2.1 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_9 PF13454.6 ABK75315.1 - 0.026 14.5 11.3 0.23 11.4 0.6 3.5 4 0 0 4 4 4 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 ABK75315.1 - 0.045 13.0 11.4 0.3 10.4 0.4 2.9 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 ABK75315.1 - 0.053 13.7 3.8 3 8.2 0.1 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 ABK75315.1 - 0.059 12.7 3.1 0.049 12.9 0.6 2.0 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.18 ABK75315.1 - 0.11 12.4 3.7 0.17 11.7 0.3 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 ABK75315.1 - 0.3 10.3 5.6 6.9 5.8 0.4 2.8 2 1 1 3 3 3 0 FAD binding domain DAO PF01266.24 ABK75315.1 - 0.37 10.3 20.7 3.1 7.3 4.7 4.4 3 1 1 4 4 4 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ABK75315.1 - 3.1 6.8 15.5 0.61 9.1 1.6 3.8 3 1 2 5 5 5 0 FAD binding domain COXG PF06240.13 ABK75316.1 - 4.6e-23 81.5 0.1 6e-23 81.1 0.1 1.1 1 0 0 1 1 1 1 Carbon monoxide dehydrogenase subunit G (CoxG) Polyketide_cyc2 PF10604.9 ABK75316.1 - 0.00097 19.4 0.6 0.0016 18.7 0.6 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 ABK75316.1 - 0.1 12.8 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein HTH_11 PF08279.12 ABK75317.1 - 1.4e-14 53.8 0.0 2.9e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 HTH domain WYL PF13280.6 ABK75317.1 - 8.7e-14 51.9 0.1 1.4e-13 51.3 0.1 1.3 1 0 0 1 1 1 1 WYL domain Rrf2 PF02082.20 ABK75317.1 - 3e-05 24.3 0.0 5.7e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator HTH_DeoR PF08220.12 ABK75317.1 - 3.1e-05 23.6 0.0 5.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain MarR_2 PF12802.7 ABK75317.1 - 0.005 16.7 0.3 0.23 11.4 0.1 2.6 2 0 0 2 2 2 1 MarR family HTH_36 PF13730.6 ABK75317.1 - 0.0064 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 ABK75317.1 - 0.01 15.6 0.2 0.032 14.0 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain HTH_28 PF13518.6 ABK75317.1 - 0.019 15.1 0.4 0.17 12.1 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain TrmB PF01978.19 ABK75317.1 - 0.027 14.4 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Fe_dep_repress PF01325.19 ABK75317.1 - 0.036 14.3 0.0 1.4 9.2 0.0 2.3 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain HTH_IclR PF09339.10 ABK75317.1 - 0.048 13.5 0.1 0.24 11.2 0.0 2.1 2 0 0 2 2 2 0 IclR helix-turn-helix domain Dimerisation2 PF16864.5 ABK75317.1 - 0.063 13.3 0.1 1.4 9.0 0.0 2.6 3 0 0 3 3 3 0 Dimerisation domain HTH_38 PF13936.6 ABK75317.1 - 0.065 13.0 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_ECF PF07638.11 ABK75317.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 ECF sigma factor HTH_10 PF04967.12 ABK75317.1 - 0.15 11.8 0.1 0.43 10.4 0.0 1.7 2 0 0 2 2 2 0 HTH DNA binding domain Amidase PF01425.21 ABK75318.1 - 1.6e-112 376.7 0.8 2.1e-112 376.3 0.8 1.1 1 0 0 1 1 1 1 Amidase Septum_form PF13845.6 ABK75319.1 - 4.8e-11 42.6 0.2 2.3e-10 40.4 0.2 1.6 1 1 0 1 1 1 1 Septum formation DUF3040 PF11239.8 ABK75319.1 - 0.028 14.7 0.2 0.046 14.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF3357 PF11837.8 ABK75319.1 - 0.08 13.4 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DUF3094 PF11293.8 ABK75319.1 - 0.15 11.8 1.1 0.25 11.1 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) Pex14_N PF04695.13 ABK75319.1 - 0.63 10.7 3.8 0.93 10.1 3.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Acyl-CoA_dh_1 PF00441.24 ABK75320.1 - 5.2e-41 140.3 6.1 8.1e-41 139.7 6.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK75320.1 - 5.3e-27 94.7 0.1 2e-26 92.8 0.1 2.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ABK75320.1 - 4e-25 87.8 0.1 6.8e-25 87.1 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ABK75320.1 - 3.1e-14 53.4 5.7 6.4e-14 52.4 5.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Usp PF00582.26 ABK75323.1 - 3.2e-40 137.9 11.5 1.3e-22 80.8 2.6 2.2 2 0 0 2 2 2 2 Universal stress protein family Fst_toxin PF13955.6 ABK75323.1 - 3.2 7.8 5.4 17 5.4 0.1 2.8 2 0 0 2 2 2 0 Toxin Fst, type I toxin-antitoxin system BPD_transp_2 PF02653.16 ABK75324.1 - 1.3e-30 106.5 55.1 1.6e-30 106.2 55.1 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component TMEM171 PF15471.6 ABK75324.1 - 0.025 13.6 0.5 0.025 13.6 0.5 1.9 2 1 0 2 2 2 0 Transmembrane protein family 171 Pam17 PF08566.10 ABK75324.1 - 2.1 8.2 9.1 0.62 9.9 1.3 2.4 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 IMPDH PF00478.25 ABK75325.1 - 1.6e-35 122.8 3.3 1.4e-34 119.6 1.8 2.0 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 ABK75325.1 - 2.3e-09 36.8 6.1 2.3e-09 36.8 6.1 1.7 2 1 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 ABK75325.1 - 0.00011 21.8 14.1 0.024 14.0 2.7 3.1 1 1 2 3 3 3 3 Nitronate monooxygenase Glu_synthase PF01645.17 ABK75325.1 - 0.00014 21.2 1.4 0.00024 20.4 1.4 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 ABK75325.1 - 0.0053 16.1 8.6 0.12 11.7 2.0 2.3 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG NanE PF04131.14 ABK75325.1 - 0.014 14.6 0.4 0.38 9.9 0.0 2.4 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 ABK75325.1 - 0.085 12.3 0.4 4.7 6.6 0.0 2.2 1 1 1 2 2 2 0 Histidine biosynthesis protein adh_short_C2 PF13561.6 ABK75326.1 - 4.9e-54 183.4 4.4 5.6e-54 183.2 4.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK75326.1 - 3.5e-52 176.7 0.4 4.3e-52 176.4 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK75326.1 - 5e-12 46.1 1.6 1.1e-11 45.0 1.6 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK75326.1 - 7.8e-05 22.2 2.0 0.00029 20.4 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ABK75326.1 - 0.0024 17.8 1.1 0.0046 16.9 1.1 1.7 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 ABK75326.1 - 0.0056 15.8 0.1 0.0099 15.0 0.1 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain THF_DHG_CYH_C PF02882.19 ABK75326.1 - 0.03 13.7 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Phage_BR0599 PF09356.10 ABK75326.1 - 0.061 13.7 0.2 0.23 11.8 0.1 2.0 2 1 0 2 2 2 0 Phage conserved hypothetical protein BR0599 Eno-Rase_NADH_b PF12242.8 ABK75326.1 - 0.063 13.0 1.0 1 9.2 0.2 2.5 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DFP PF04127.15 ABK75326.1 - 0.083 12.7 0.2 0.14 12.0 0.2 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NmrA PF05368.13 ABK75326.1 - 0.26 10.8 3.5 1.4 8.4 1.7 2.7 2 1 0 2 2 2 0 NmrA-like family ADH_zinc_N PF00107.26 ABK75326.1 - 0.29 11.1 3.5 0.75 9.8 1.9 2.5 2 1 0 2 2 2 0 Zinc-binding dehydrogenase ADK PF00406.22 ABK75327.1 - 2.4e-53 180.3 0.0 2.8e-53 180.1 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 ABK75327.1 - 5.4e-30 104.6 0.0 6.6e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ABK75327.1 - 2.3e-09 37.5 0.0 3.1e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ABK75327.1 - 1.4e-07 32.1 0.0 2.7e-07 31.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 ABK75327.1 - 0.00025 20.9 0.4 0.0011 18.8 0.0 1.9 2 0 0 2 2 2 1 Cytidylate kinase Thymidylate_kin PF02223.17 ABK75327.1 - 0.0034 17.1 0.0 1.1 8.9 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_28 PF13521.6 ABK75327.1 - 0.0092 16.2 0.0 0.012 15.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 ABK75327.1 - 0.031 14.7 0.2 0.064 13.7 0.0 1.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ABK75327.1 - 0.043 13.8 0.2 0.13 12.2 0.1 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) dNK PF01712.19 ABK75327.1 - 0.043 13.7 0.1 1.8 8.4 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase MarR PF01047.22 ABK75328.1 - 2.6e-14 52.9 0.0 4.7e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 ABK75328.1 - 5.7e-10 38.9 0.0 1.1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 ABK75328.1 - 2e-08 34.6 0.0 3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_34 PF13601.6 ABK75328.1 - 1.5e-05 25.1 0.0 2.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HxlR PF01638.17 ABK75328.1 - 0.00096 19.0 0.1 0.0015 18.4 0.1 1.3 1 0 0 1 1 1 1 HxlR-like helix-turn-helix PadR PF03551.14 ABK75328.1 - 0.0036 17.2 0.1 0.0059 16.5 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family Replic_Relax PF13814.6 ABK75328.1 - 0.03 14.4 0.1 0.037 14.1 0.1 1.1 1 0 0 1 1 1 0 Replication-relaxation TrmB PF01978.19 ABK75328.1 - 0.037 13.9 0.0 0.077 12.9 0.0 1.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 ABK75328.1 - 0.04 13.5 0.1 0.16 11.5 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_36 PF13730.6 ABK75328.1 - 0.15 12.0 0.1 8.7 6.4 0.0 2.4 2 1 0 2 2 2 0 Helix-turn-helix domain Ribosom_S30AE_C PF16321.5 ABK75329.1 - 1.9e-23 81.9 0.0 4.7e-23 80.6 0.0 1.7 1 0 0 1 1 1 1 Sigma 54 modulation/S30EA ribosomal protein C terminus Ribosomal_S30AE PF02482.19 ABK75329.1 - 8.7e-21 74.5 0.4 1.7e-20 73.6 0.3 1.5 2 0 0 2 2 2 1 Sigma 54 modulation protein / S30EA ribosomal protein CMD PF02627.20 ABK75330.1 - 2.4e-08 33.9 0.7 3.7e-08 33.3 0.7 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Thy1 PF02511.15 ABK75331.1 - 1.2e-55 188.2 0.4 1.5e-55 187.9 0.4 1.0 1 0 0 1 1 1 1 Thymidylate synthase complementing protein CHASE3 PF05227.13 ABK75331.1 - 0.015 15.2 0.7 0.021 14.8 0.7 1.2 1 0 0 1 1 1 0 CHASE3 domain Acyl-CoA_dh_1 PF00441.24 ABK75332.1 - 5.3e-44 150.0 1.3 9.1e-44 149.3 1.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 ABK75332.1 - 1.4e-21 77.1 1.7 3e-21 76.1 1.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK75332.1 - 1.4e-16 60.5 0.0 2.5e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ABK75332.1 - 3.1e-13 50.4 0.5 8e-13 49.0 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 ABK75332.1 - 0.058 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal DUF222 PF02720.17 ABK75333.1 - 6.3e-41 140.8 24.9 1.9e-40 139.3 14.9 2.5 3 0 0 3 3 3 2 Domain of unknown function (DUF222) Trypan_PARP PF05887.11 ABK75333.1 - 0.017 15.1 9.3 0.037 14.0 9.3 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) F420H2_quin_red PF04075.14 ABK75334.1 - 2.7e-44 150.4 0.2 3e-44 150.3 0.2 1.0 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase NMT1_2 PF13379.6 ABK75334.1 - 0.14 11.8 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 NMT1-like family DoxX_2 PF13564.6 ABK75335.1 - 8.5e-11 41.9 7.2 9.8e-11 41.7 7.2 1.0 1 0 0 1 1 1 1 DoxX-like family LeuA_dimer PF08502.10 ABK75336.1 - 0.001 18.9 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain DUF4350 PF14258.6 ABK75336.1 - 0.055 13.9 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) DUF836 PF05768.14 ABK75338.1 - 7.6e-16 58.3 0.0 8.2e-16 58.2 0.0 1.0 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) TraF PF13728.6 ABK75338.1 - 0.065 13.1 0.0 0.072 12.9 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Glutaredoxin PF00462.24 ABK75338.1 - 0.072 13.3 0.0 0.098 12.9 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin CT_A_B PF02626.15 ABK75339.1 - 9.3e-87 291.0 0.1 1.1e-86 290.8 0.1 1.0 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B LPG_synthase_TM PF03706.13 ABK75340.1 - 9.9e-35 120.5 43.7 9.9e-35 120.5 43.7 3.8 3 1 0 3 3 3 1 Lysylphosphatidylglycerol synthase TM region Pkinase PF00069.25 ABK75340.1 - 0.041 13.3 0.0 0.064 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain PCRF PF03462.18 ABK75341.1 - 4.2e-57 193.2 0.6 1.3e-56 191.6 0.1 1.8 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 ABK75341.1 - 4.5e-37 126.5 0.3 1.5e-36 124.9 0.0 1.9 2 0 0 2 2 2 1 RF-1 domain ABC_tran_CTD PF16326.5 ABK75341.1 - 0.021 15.1 0.1 0.021 15.1 0.1 3.5 3 1 2 5 5 5 0 ABC transporter C-terminal domain Ntox28 PF15605.6 ABK75341.1 - 0.055 13.7 0.3 0.055 13.7 0.3 2.0 2 0 0 2 2 2 0 Bacterial toxin 28 MIR PF02815.19 ABK75341.1 - 0.068 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 MIR domain Fic_N PF13784.6 ABK75341.1 - 0.072 13.1 0.7 1.2 9.2 0.1 2.4 2 0 0 2 2 2 0 Fic/DOC family N-terminal DUF4349 PF14257.6 ABK75341.1 - 0.54 9.7 4.8 1.1 8.7 3.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) MmgE_PrpD PF03972.14 ABK75342.1 - 2.3e-114 382.4 0.2 2.6e-114 382.2 0.2 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Ribosomal_S3_C PF00189.20 ABK75343.1 - 6.5e-37 125.9 0.2 1.2e-36 125.0 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 ABK75343.1 - 2e-19 69.2 0.8 3.3e-19 68.5 0.8 1.4 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 ABK75343.1 - 0.00013 21.7 0.4 0.00031 20.5 0.4 1.6 1 0 0 1 1 1 1 KH domain RNase_T PF00929.24 ABK75344.1 - 3.5e-21 76.4 0.0 4.8e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 ABK75344.1 - 9e-05 22.5 0.0 0.00027 21.0 0.0 1.7 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like DNA_pol_A_exo1 PF01612.20 ABK75344.1 - 0.04 13.6 0.0 0.085 12.6 0.0 1.5 2 0 0 2 2 2 0 3'-5' exonuclease AA_permease_2 PF13520.6 ABK75345.1 - 2.2e-53 181.6 41.2 3.4e-53 181.0 41.1 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ABK75345.1 - 8.1e-31 107.1 38.1 1.1e-30 106.7 38.1 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 ABK75345.1 - 2.7e-10 40.1 7.5 2.7e-10 40.1 7.5 3.9 5 0 0 5 5 5 1 C-terminus of AA_permease MDMPI_N PF11716.8 ABK75346.1 - 6.6e-25 88.4 6.8 6.6e-25 88.4 6.8 2.0 2 0 0 2 2 2 1 Mycothiol maleylpyruvate isomerase N-terminal domain MDMPI_C PF07398.11 ABK75346.1 - 8.5e-15 55.4 2.9 8.5e-15 55.4 2.9 1.8 2 0 0 2 2 2 1 MDMPI C-terminal domain DUF664 PF04978.12 ABK75346.1 - 0.012 16.1 0.0 0.025 15.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF664) DinB_2 PF12867.7 ABK75346.1 - 0.043 14.3 2.6 0.097 13.2 2.6 1.6 1 1 0 1 1 1 0 DinB superfamily TOBE_3 PF12857.7 ABK75347.1 - 0.066 13.1 0.1 0.24 11.3 0.1 2.0 1 0 0 1 1 1 0 TOBE-like domain YkuD PF03734.14 ABK75348.1 - 8.7e-19 68.4 0.0 1.4e-18 67.7 0.0 1.3 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain Big_10 PF17964.1 ABK75348.1 - 5.9e-17 62.2 0.4 9e-17 61.6 0.4 1.3 1 0 0 1 1 1 1 Bacterial Ig domain Elong-fact-P_C PF09285.11 ABK75349.1 - 6.5e-27 93.0 0.4 1.9e-26 91.5 0.0 1.9 2 0 0 2 2 2 1 Elongation factor P, C-terminal EFP_N PF08207.12 ABK75349.1 - 6.8e-27 93.3 0.5 1.3e-26 92.4 0.3 1.6 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain EFP PF01132.20 ABK75349.1 - 6.3e-20 70.9 0.0 1e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain DUF5042 PF16445.5 ABK75349.1 - 0.065 11.6 0.0 2.3 6.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5042) GatD_N PF18195.1 ABK75349.1 - 0.18 11.2 0.1 20 4.6 0.0 2.5 2 0 0 2 2 2 0 GatD N-terminal domain Hemerythrin PF01814.23 ABK75350.1 - 4.7e-14 53.1 5.8 9.1e-14 52.2 5.8 1.5 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain TPR_19 PF14559.6 ABK75350.1 - 0.067 13.7 0.1 0.12 12.9 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat DnaB_C PF03796.15 ABK75351.1 - 7.7e-92 307.2 0.0 9.7e-80 267.6 0.0 2.4 2 1 1 3 3 3 2 DnaB-like helicase C terminal domain DnaB PF00772.21 ABK75351.1 - 2.2e-32 111.2 0.0 4.4e-32 110.2 0.0 1.6 1 0 0 1 1 1 1 DnaB-like helicase N terminal domain LAGLIDADG_3 PF14528.6 ABK75351.1 - 1.1e-26 92.9 0.0 8.6e-23 80.5 0.0 2.6 2 0 0 2 2 2 2 LAGLIDADG-like domain Intein_splicing PF14890.6 ABK75351.1 - 4.1e-23 81.8 0.0 8.8e-23 80.7 0.0 1.6 1 0 0 1 1 1 1 Intein splicing domain AAA_25 PF13481.6 ABK75351.1 - 1e-09 38.2 0.2 1.5e-07 31.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 ABK75351.1 - 0.021 14.3 0.1 0.042 13.2 0.1 1.4 1 0 0 1 1 1 0 Bacterial TniB protein PT-HINT PF07591.11 ABK75351.1 - 0.079 13.2 0.0 0.73 10.1 0.0 2.2 2 0 0 2 2 2 0 Pretoxin HINT domain ATPase PF06745.13 ABK75351.1 - 0.093 12.1 0.7 0.57 9.5 0.0 2.2 2 0 0 2 2 2 0 KaiC adh_short_C2 PF13561.6 ABK75352.1 - 3.9e-57 193.5 4.0 4.6e-57 193.3 4.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK75352.1 - 7.9e-46 156.0 1.5 7.9e-46 156.0 1.5 1.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 ABK75352.1 - 1.6e-10 41.2 2.0 3.4e-10 40.1 1.7 1.6 1 1 1 2 2 2 2 KR domain Ribosomal_S5_C PF03719.15 ABK75352.1 - 0.1 12.0 1.6 0.79 9.2 0.2 2.7 3 0 0 3 3 3 0 Ribosomal protein S5, C-terminal domain Methyltransf_31 PF13847.6 ABK75352.1 - 0.16 11.7 0.0 0.26 11.1 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain HTH_Tnp_1 PF01527.20 ABK75353.1 - 2.7e-07 30.8 0.1 3.6e-07 30.4 0.1 1.2 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 ABK75353.1 - 8.6e-05 22.6 0.1 0.00015 21.8 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 ABK75353.1 - 0.00096 18.9 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain Cep57_CLD PF14073.6 ABK75353.1 - 0.0022 18.1 0.0 0.0022 18.1 0.0 1.1 1 0 0 1 1 1 1 Centrosome localisation domain of Cep57 LZ_Tnp_IS481 PF13011.6 ABK75353.1 - 0.015 15.8 0.0 0.03 14.8 0.0 1.5 2 0 0 2 2 2 0 leucine-zipper of insertion element IS481 HTH_Tnp_ISL3 PF13542.6 ABK75353.1 - 0.019 14.4 0.0 0.04 13.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_10 PF04967.12 ABK75353.1 - 0.028 14.2 0.1 0.12 12.1 0.0 2.1 3 0 0 3 3 3 0 HTH DNA binding domain HTH_Tnp_1_2 PF13022.6 ABK75353.1 - 0.078 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_Tnp_4 PF13613.6 ABK75353.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease CoA_transf_3 PF02515.17 ABK75354.1 - 2e-88 297.0 0.1 2.3e-88 296.8 0.1 1.0 1 0 0 1 1 1 1 CoA-transferase family III CobD_Cbib PF03186.13 ABK75355.1 - 0.00082 18.7 0.2 0.0011 18.3 0.2 1.2 1 0 0 1 1 1 1 CobD/Cbib protein TPR_21 PF09976.9 ABK75355.1 - 0.0081 15.9 2.7 0.0081 15.9 2.7 1.9 2 1 0 2 2 2 1 Tetratricopeptide repeat-like domain DUF2909 PF11137.8 ABK75355.1 - 0.066 13.1 0.2 0.11 12.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) DUF4307 PF14155.6 ABK75355.1 - 0.12 12.2 5.3 0.72 9.7 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) RskA PF10099.9 ABK75355.1 - 0.15 12.4 6.2 0.27 11.5 6.2 1.4 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Amidohydro_2 PF04909.14 ABK75356.1 - 5.5e-37 128.1 4.5 6.3e-37 127.9 4.5 1.0 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 ABK75356.1 - 5.9e-05 22.5 0.0 0.00061 19.2 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase family RskA PF10099.9 ABK75357.1 - 0.14 12.5 9.2 0.2 11.9 9.1 1.4 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Calici_coat PF00915.20 ABK75357.1 - 0.31 9.9 2.1 0.41 9.5 0.0 1.9 1 1 1 2 2 2 0 Calicivirus coat protein TauE PF01925.19 ABK75358.1 - 1e-32 113.7 38.5 1e-32 113.7 38.5 1.6 2 0 0 2 2 2 1 Sulfite exporter TauE/SafE HpcH_HpaI PF03328.14 ABK75359.1 - 1.2e-43 148.8 0.1 1.7e-43 148.4 0.1 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 ABK75359.1 - 7.5e-07 28.6 0.0 0.008 15.4 0.0 2.2 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold DUF3298 PF11738.8 ABK75360.1 - 5.6e-12 46.5 0.0 9.9e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3298) tRNA-synt_His PF13393.6 ABK75361.1 - 6.7e-46 157.0 0.2 3.3e-45 154.7 0.0 2.0 2 1 0 2 2 2 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 ABK75361.1 - 1.8e-19 70.4 0.0 4.1e-18 66.0 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 ABK75361.1 - 5.5e-13 48.9 0.0 1.2e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2d PF01409.20 ABK75361.1 - 0.003 17.1 0.1 1.7 8.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Homoserine_dh PF00742.19 ABK75362.1 - 8.9e-68 227.6 1.3 1.1e-67 227.3 0.4 1.6 2 0 0 2 2 2 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 ABK75362.1 - 4.3e-24 85.4 0.6 4.3e-24 85.4 0.6 2.6 3 0 0 3 3 3 1 Homoserine dehydrogenase, NAD binding domain ACT PF01842.25 ABK75362.1 - 4e-12 45.7 0.1 1.2e-11 44.1 0.1 1.9 1 0 0 1 1 1 1 ACT domain Sacchrp_dh_NADP PF03435.18 ABK75362.1 - 0.039 14.2 0.6 0.28 11.5 0.6 2.3 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GFO_IDH_MocA PF01408.22 ABK75362.1 - 0.051 14.4 0.1 0.15 12.9 0.1 1.9 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DUF1611_N PF17396.2 ABK75362.1 - 0.22 11.8 1.2 0.79 10.0 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1611_N) Rossmann-like domain NapD PF03927.13 ABK75362.1 - 1.3 9.1 3.9 1.8 8.7 1.2 2.7 3 1 0 3 3 3 0 NapD protein DDE_Tnp_ISL3 PF01610.17 ABK75363.1 - 1.6e-64 217.9 0.0 2.1e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Transposase zf-ISL3 PF14690.6 ABK75363.1 - 1.1e-09 38.8 4.6 1.8e-09 38.1 2.5 2.5 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HTH_Tnp_ISL3 PF13542.6 ABK75363.1 - 2.4e-08 33.2 1.6 7e-08 31.8 1.6 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 ABC_tran PF00005.27 ABK75364.1 - 3e-46 157.3 0.0 5e-27 95.1 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ABK75364.1 - 2.6e-05 24.2 0.0 0.22 11.3 0.0 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ABK75364.1 - 7.8e-05 22.3 1.0 0.0091 15.7 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 ABK75364.1 - 0.00017 22.0 0.3 0.23 11.8 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 ABK75364.1 - 0.00025 21.0 0.5 0.19 11.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase SMC_N PF02463.19 ABK75364.1 - 0.0012 18.3 0.0 3.4 7.0 0.1 2.9 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 ABK75364.1 - 0.0031 17.2 3.9 0.35 10.6 0.1 3.1 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 ABK75364.1 - 0.0063 16.6 0.3 5.9 7.0 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase MeaB PF03308.16 ABK75364.1 - 0.052 12.5 1.1 0.34 9.9 0.3 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Ploopntkinase3 PF18751.1 ABK75364.1 - 0.081 12.8 0.3 3.4 7.5 0.0 2.9 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 AAA_24 PF13479.6 ABK75364.1 - 0.12 12.1 0.8 4.6 6.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_27 PF13514.6 ABK75364.1 - 0.13 11.8 0.1 0.66 9.5 0.1 2.0 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 ABK75364.1 - 0.19 11.5 1.3 0.71 9.6 0.1 2.3 3 0 0 3 3 3 0 MukB N-terminal AAA_23 PF13476.6 ABK75364.1 - 0.41 11.1 1.2 0.46 10.9 0.1 1.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ABK75364.1 - 1.3 8.5 5.7 15 5.1 0.7 3.8 3 1 0 3 3 3 0 AAA domain FAD_binding_3 PF01494.19 ABK75365.1 - 4.1e-14 52.6 0.0 9.2e-14 51.4 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 ABK75365.1 - 7.1e-05 22.6 0.4 0.0043 16.7 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ABK75365.1 - 0.00068 19.8 0.0 0.0023 18.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ABK75365.1 - 0.0062 17.1 0.0 0.028 15.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ABK75365.1 - 0.038 13.2 0.0 0.19 10.9 0.0 2.1 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase OpuAC PF04069.12 ABK75366.1 - 1.5e-19 70.6 0.1 1.9e-18 67.0 0.1 1.9 1 1 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system YkuD PF03734.14 ABK75368.1 - 5e-06 27.0 0.1 7.5e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain adh_short_C2 PF13561.6 ABK75369.1 - 2.1e-37 128.9 1.8 4.1e-36 124.7 1.8 2.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK75369.1 - 4.6e-30 104.5 1.8 3e-29 101.9 1.8 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK75369.1 - 1.7e-05 24.8 0.4 2.9e-05 24.1 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK75369.1 - 0.0037 16.8 0.1 0.0064 16.0 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ABK75369.1 - 0.017 14.3 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ABC_tran PF00005.27 ABK75370.1 - 8.2e-51 172.1 0.1 1.5e-25 90.3 0.0 2.2 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ABK75370.1 - 9.9e-09 35.4 0.0 0.002 18.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ABK75370.1 - 5e-05 23.3 1.5 0.0019 18.2 0.2 3.0 4 0 0 4 4 4 1 RsgA GTPase MMR_HSR1 PF01926.23 ABK75370.1 - 0.00045 20.3 1.1 0.041 14.0 0.1 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.29 ABK75370.1 - 0.00053 20.4 1.0 0.011 16.1 0.2 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 ABK75370.1 - 0.00084 19.0 0.8 0.0048 16.6 0.2 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 ABK75370.1 - 0.004 17.4 0.7 0.051 13.8 0.1 2.7 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.19 ABK75370.1 - 0.004 16.6 0.4 0.78 9.1 0.1 2.9 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ABK75370.1 - 0.004 17.7 0.8 0.01 16.4 0.1 1.8 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 ABK75370.1 - 0.0049 16.9 0.4 0.7 9.9 0.1 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 ABK75370.1 - 0.0073 15.9 0.3 1.8 8.2 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 ABK75370.1 - 0.013 14.8 1.6 0.55 9.5 0.2 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_13 PF13166.6 ABK75370.1 - 0.021 13.5 0.0 0.03 13.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ABK75370.1 - 0.023 14.4 7.8 0.018 14.8 1.8 2.8 2 1 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 ABK75370.1 - 0.023 13.5 1.3 7.4 5.2 0.1 3.1 2 1 0 2 2 2 0 Predicted ATPase of the ABC class NTPase_1 PF03266.15 ABK75370.1 - 0.031 14.2 2.1 1.2 9.1 0.0 2.7 3 0 0 3 3 3 0 NTPase MukB PF04310.12 ABK75370.1 - 0.034 13.9 0.5 0.085 12.7 0.1 1.8 2 0 0 2 2 2 0 MukB N-terminal SbcCD_C PF13558.6 ABK75370.1 - 0.04 14.2 0.0 26 5.1 0.0 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 ABK75370.1 - 0.04 14.3 0.9 4.4 7.7 0.1 2.6 2 1 0 2 2 2 0 AAA ATPase domain AAA_15 PF13175.6 ABK75370.1 - 0.044 13.5 0.1 0.068 12.9 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 ABK75370.1 - 0.46 9.3 1.9 4.2 6.2 0.0 3.1 4 0 0 4 4 4 0 Type IV secretion-system coupling protein DNA-binding domain Lactamase_B PF00753.27 ABK75371.1 - 2.4e-26 93.0 6.2 3.2e-26 92.6 6.2 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ABK75371.1 - 0.048 13.2 0.1 0.085 12.4 0.1 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Pyr_redox_2 PF07992.14 ABK75372.1 - 3.1e-44 151.4 0.0 3.7e-44 151.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ABK75372.1 - 2.4e-10 40.8 0.1 4.6e-05 23.9 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ABK75372.1 - 0.0031 16.7 0.0 0.78 8.8 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ABK75372.1 - 0.028 14.6 0.1 0.14 12.5 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ABK75372.1 - 0.053 13.5 0.1 0.7 9.9 0.0 2.7 4 0 0 4 4 4 0 FAD-NAD(P)-binding RNA_pol_A_CTD PF03118.15 ABK75372.1 - 0.16 11.7 0.1 4.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain Ribosomal_L3 PF00297.22 ABK75373.1 - 6.5e-19 68.1 9.3 2.4e-18 66.3 3.3 2.9 2 1 1 3 3 3 3 Ribosomal protein L3 PseudoU_synth_1 PF01416.20 ABK75374.1 - 3.7e-29 101.3 0.0 3.3e-23 82.2 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase adh_short_C2 PF13561.6 ABK75375.1 - 2.4e-46 158.2 4.2 2.9e-46 157.9 4.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK75375.1 - 2.9e-45 154.1 3.5 3.8e-45 153.7 3.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK75375.1 - 4e-06 26.9 5.0 0.00015 21.7 3.1 2.5 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 ABK75375.1 - 0.00014 21.4 0.3 0.00019 21.0 0.3 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 ABK75375.1 - 0.00088 19.3 2.1 0.0018 18.3 2.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.20 ABK75375.1 - 0.0093 16.0 0.2 0.016 15.3 0.2 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ATPgrasp_N PF18130.1 ABK75375.1 - 0.081 13.5 0.1 0.19 12.3 0.1 1.5 1 0 0 1 1 1 0 ATP-grasp N-terminal domain LysE PF01810.18 ABK75376.1 - 2.5e-27 95.6 14.1 2.8e-27 95.4 14.1 1.0 1 0 0 1 1 1 1 LysE type translocator Hydrolase_4 PF12146.8 ABK75377.1 - 9.1e-16 57.8 0.7 1.7e-10 40.6 0.2 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ABK75377.1 - 3.8e-10 40.7 8.2 4.9e-10 40.4 8.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ABK75377.1 - 4.2e-09 36.2 0.3 2.5e-05 23.9 0.2 2.4 2 1 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 ABK75377.1 - 5.4e-08 32.6 0.1 5.7e-06 26.0 0.0 2.3 2 0 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.12 ABK75377.1 - 5.7e-08 31.8 0.1 0.00035 19.4 0.0 2.5 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 ABK75377.1 - 1.2e-07 31.7 0.4 2.1e-07 30.8 0.2 1.5 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 ABK75377.1 - 1.1e-06 28.5 0.1 0.00046 19.9 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold PAF-AH_p_II PF03403.13 ABK75377.1 - 0.00013 20.6 0.2 0.24 9.9 0.0 2.1 1 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_4 PF08386.10 ABK75377.1 - 0.042 14.0 0.2 0.22 11.7 0.0 2.2 3 0 0 3 3 3 0 TAP-like protein DUF1100 PF06500.11 ABK75377.1 - 0.043 12.6 0.0 0.18 10.5 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1100) TPR_4 PF07721.14 ABK75378.1 - 1.9 9.4 0.1 1.9 9.4 0.1 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L1 PF00687.21 ABK75379.1 - 5.4e-53 179.8 0.0 6.6e-53 179.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF222 PF02720.17 ABK75381.1 - 2e-58 198.3 3.7 3.8e-58 197.4 3.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF222) TetR_C_21 PF17926.1 ABK75381.1 - 0.011 15.8 0.0 0.04 14.1 0.0 1.9 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain AcetDehyd-dimer PF09290.11 ABK75382.1 - 5.6e-63 211.2 0.2 1e-62 210.4 0.2 1.4 1 0 0 1 1 1 1 Prokaryotic acetaldehyde dehydrogenase, dimerisation Semialdhyde_dh PF01118.24 ABK75382.1 - 8.5e-13 48.8 0.1 3e-12 47.0 0.1 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 ABK75382.1 - 0.0014 19.5 0.0 0.003 18.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 ABK75382.1 - 0.011 16.3 0.1 0.03 14.9 0.1 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent CoA_binding PF02629.19 ABK75382.1 - 0.015 16.0 0.1 0.039 14.6 0.1 1.9 1 1 0 1 1 1 0 CoA binding domain DapB_N PF01113.20 ABK75382.1 - 0.068 13.3 1.6 0.084 13.0 0.1 1.9 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_3 PF03447.16 ABK75382.1 - 0.076 13.7 0.0 0.22 12.2 0.0 1.8 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Phage_integrase PF00589.22 ABK75383.1 - 1.2e-45 155.4 0.0 1.6e-45 155.0 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 ABK75383.1 - 1.6e-19 69.9 0.9 4e-19 68.7 0.9 1.7 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain RuvC PF02075.17 ABK75383.1 - 0.051 13.5 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 Crossover junction endodeoxyribonuclease RuvC Phage_int_SAM_5 PF13102.6 ABK75383.1 - 0.25 11.7 0.0 2.2 8.7 0.0 2.1 1 1 0 1 1 1 0 Phage integrase SAM-like domain TPP_enzyme_C PF02775.21 ABK75384.1 - 5.4e-42 143.2 0.7 1e-41 142.3 0.1 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.18 ABK75384.1 - 6.9e-40 136.5 8.7 1.1e-38 132.5 0.2 2.7 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 ABK75384.1 - 1.5e-32 112.2 0.1 2.7e-32 111.4 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 ABK75384.1 - 0.034 13.9 0.1 0.066 12.9 0.1 1.5 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg ATP-synt_F PF01990.17 ABK75384.1 - 0.076 13.3 0.0 2 8.8 0.0 2.8 3 0 0 3 3 3 0 ATP synthase (F/14-kDa) subunit ROK PF00480.20 ABK75386.1 - 2.5e-44 151.9 0.2 3.5e-44 151.5 0.2 1.1 1 0 0 1 1 1 1 ROK family MarR_2 PF12802.7 ABK75386.1 - 6e-07 29.3 0.3 5.2e-06 26.3 0.5 2.4 2 0 0 2 2 2 1 MarR family HTH_IclR PF09339.10 ABK75386.1 - 5.1e-05 23.0 1.1 5.1e-05 23.0 1.1 2.5 4 0 0 4 4 4 1 IclR helix-turn-helix domain HTH_24 PF13412.6 ABK75386.1 - 0.0018 17.8 0.2 0.0038 16.8 0.2 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding FeoC PF09012.10 ABK75386.1 - 0.0049 16.9 0.0 0.063 13.4 0.0 2.6 3 0 0 3 3 3 1 FeoC like transcriptional regulator HTH_27 PF13463.6 ABK75386.1 - 0.011 16.2 0.1 0.026 15.0 0.1 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain MarR PF01047.22 ABK75386.1 - 0.016 15.1 0.1 0.032 14.1 0.1 1.5 1 0 0 1 1 1 0 MarR family TrmB PF01978.19 ABK75386.1 - 0.055 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 ABK75386.1 - 0.48 10.4 2.5 0.64 10.0 0.3 2.4 3 1 0 3 3 3 0 Crp-like helix-turn-helix domain Glyoxalase PF00903.25 ABK75387.1 - 1.2e-07 32.0 0.2 1.9e-07 31.3 0.2 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ABK75387.1 - 9.7e-06 26.3 0.7 1.5e-05 25.7 0.7 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 ABK75387.1 - 0.0015 18.8 0.1 0.003 17.8 0.1 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily GSDH PF07995.11 ABK75388.1 - 0.00019 20.9 0.1 0.0028 17.0 0.0 2.7 2 1 0 2 2 2 1 Glucose / Sorbosone dehydrogenase SGL PF08450.12 ABK75388.1 - 0.0032 17.1 0.1 0.96 9.0 0.0 2.7 1 1 1 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region DUF3558 PF12079.8 ABK75388.1 - 0.054 13.5 4.1 0.11 12.5 4.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) US22 PF02393.16 ABK75388.1 - 0.085 13.1 0.1 2.1 8.6 0.0 2.6 2 1 0 2 2 2 0 US22 like GCV_T PF01571.21 ABK75389.1 - 4e-82 275.4 0.0 4.8e-82 275.2 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 ABK75389.1 - 3.5e-17 62.1 0.2 7.7e-17 61.0 0.2 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain 7TM_transglut PF14402.6 ABK75389.1 - 0.22 11.0 0.1 0.32 10.4 0.1 1.2 1 0 0 1 1 1 0 7 transmembrane helices usually fused to an inactive transglutaminase MLTR_LBD PF17765.1 ABK75390.1 - 1.2e-39 136.1 8.3 1.2e-39 136.1 8.3 2.0 2 0 0 2 2 2 1 MmyB-like transcription regulator ligand binding domain HTH_31 PF13560.6 ABK75390.1 - 3e-19 69.1 9.9 3e-19 69.1 9.9 2.6 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 ABK75390.1 - 7.6e-08 32.3 0.1 1.5e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_25 PF13413.6 ABK75390.1 - 0.00096 19.0 0.5 0.003 17.4 0.5 1.8 1 1 0 1 1 1 1 Helix-turn-helix domain GRIP PF01465.20 ABK75390.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 GRIP domain DDE_Tnp_ISL3 PF01610.17 ABK75391.1 - 3.1e-50 171.1 0.0 4.4e-50 170.6 0.0 1.2 1 0 0 1 1 1 1 Transposase zf-ISL3 PF14690.6 ABK75391.1 - 3.2e-11 43.7 6.9 4.2e-10 40.1 3.8 2.9 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HTH_Tnp_ISL3 PF13542.6 ABK75391.1 - 3.4e-10 39.2 0.3 3.4e-10 39.2 0.3 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain of transposase family ISL3 Rubredoxin_2 PF18073.1 ABK75391.1 - 0.011 15.4 2.1 0.012 15.4 0.2 2.1 2 0 0 2 2 2 0 Rubredoxin metal binding domain PRA-PH PF01503.17 ABK75392.1 - 5.9e-08 33.0 0.0 6.8e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 ABK75392.1 - 4.5e-05 23.6 0.4 9.7e-05 22.5 0.2 1.6 2 0 0 2 2 2 1 MazG nucleotide pyrophosphohydrolase domain MarR_2 PF12802.7 ABK75393.1 - 5.9e-13 48.5 0.3 9.3e-13 47.9 0.3 1.3 1 0 0 1 1 1 1 MarR family MarR PF01047.22 ABK75393.1 - 1.1e-07 31.6 0.0 1.8e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_5 PF01022.20 ABK75393.1 - 3.2e-05 23.7 0.0 5.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_27 PF13463.6 ABK75393.1 - 3.4e-05 24.2 0.1 7.3e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 Winged helix DNA-binding domain TrmB PF01978.19 ABK75393.1 - 0.00017 21.4 0.0 0.00026 20.8 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.7 ABK75393.1 - 0.00025 21.0 0.1 0.00046 20.2 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 ABK75393.1 - 0.00068 19.4 0.1 0.0014 18.4 0.0 1.6 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_24 PF13412.6 ABK75393.1 - 0.0016 18.0 0.1 0.0046 16.5 0.0 1.8 1 1 1 2 2 2 1 Winged helix-turn-helix DNA-binding HxlR PF01638.17 ABK75393.1 - 0.0098 15.7 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_Crp_2 PF13545.6 ABK75393.1 - 0.011 15.7 0.1 0.021 14.8 0.1 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain EAP30 PF04157.16 ABK75393.1 - 0.035 13.4 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family DUF4334 PF14232.6 ABK75394.1 - 6.8e-26 90.0 0.0 1e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4334) GXWXG PF14231.6 ABK75394.1 - 1.7e-23 82.4 0.4 2.9e-23 81.7 0.4 1.4 1 0 0 1 1 1 1 GXWXG protein AAA_33 PF13671.6 ABK75395.1 - 2.5e-20 73.1 0.2 9.1e-19 68.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 ABK75395.1 - 1.5e-09 37.4 0.0 2.9e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 ABK75395.1 - 2.3e-08 34.6 0.0 5.3e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 ABK75395.1 - 2.4e-07 31.3 0.1 4.4e-06 27.2 0.0 2.8 2 2 2 4 4 4 1 AAA domain AAA_28 PF13521.6 ABK75395.1 - 2e-06 28.1 0.2 6.4e-06 26.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain ADK PF00406.22 ABK75395.1 - 0.00022 21.4 0.0 0.00044 20.4 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase AAA PF00004.29 ABK75395.1 - 0.00075 19.9 0.1 0.0017 18.7 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ABK75395.1 - 0.00086 19.7 0.3 0.00086 19.7 0.3 2.6 2 2 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 ABK75395.1 - 0.0012 18.7 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain KTI12 PF08433.10 ABK75395.1 - 0.003 17.1 0.0 0.005 16.3 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_19 PF13245.6 ABK75395.1 - 0.004 17.5 0.1 0.0079 16.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 ABK75395.1 - 0.0078 16.0 0.7 0.024 14.4 0.0 2.0 2 0 0 2 2 2 1 Cytidylate kinase SKI PF01202.22 ABK75395.1 - 0.0085 16.2 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase AAA_30 PF13604.6 ABK75395.1 - 0.0086 15.8 1.2 0.017 14.9 0.2 2.0 2 0 0 2 2 2 1 AAA domain IPT PF01745.16 ABK75395.1 - 0.013 14.9 0.1 0.034 13.6 0.1 1.7 2 0 0 2 2 1 0 Isopentenyl transferase CoaE PF01121.20 ABK75395.1 - 0.02 14.6 0.3 0.04 13.6 0.3 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_22 PF13401.6 ABK75395.1 - 0.039 14.2 0.1 0.16 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 ABK75395.1 - 0.044 13.8 0.2 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) CPT PF07931.12 ABK75395.1 - 0.053 13.4 1.1 0.18 11.6 0.5 2.3 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein DUF2075 PF09848.9 ABK75395.1 - 0.061 12.6 0.2 0.088 12.0 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CbiA PF01656.23 ABK75395.1 - 0.082 13.0 0.1 0.85 9.7 0.0 2.2 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Hydin_ADK PF17213.3 ABK75395.1 - 0.083 13.2 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain T2SSE PF00437.20 ABK75395.1 - 0.097 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein TsaE PF02367.17 ABK75395.1 - 0.13 12.2 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 ABK75395.1 - 0.21 11.5 0.0 0.4 10.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain ArsA_ATPase PF02374.15 ABK75395.1 - 0.33 10.1 0.3 0.5 9.5 0.3 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase DUF222 PF02720.17 ABK75396.1 - 2.9e-44 151.8 15.8 3.3e-37 128.6 14.3 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF222) Trypan_PARP PF05887.11 ABK75396.1 - 7.5 6.5 77.5 0.42 10.6 59.0 2.8 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) GerE PF00196.19 ABK75397.1 - 9.1e-19 66.8 0.2 2.8e-18 65.2 0.2 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family GAF PF01590.26 ABK75397.1 - 1.3e-07 32.3 0.1 2.4e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 ABK75397.1 - 1.3e-05 25.5 0.6 2.8e-05 24.4 0.1 1.9 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 ABK75397.1 - 2.2e-05 24.8 0.8 5e-05 23.6 0.0 2.1 3 0 0 3 3 3 1 GAF domain Sigma70_r4 PF04545.16 ABK75397.1 - 0.0004 19.8 0.1 0.0013 18.2 0.1 1.9 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 ABK75397.1 - 0.00077 19.1 1.7 0.0017 18.0 0.2 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_38 PF13936.6 ABK75397.1 - 0.032 14.0 0.1 0.083 12.7 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 ABK75397.1 - 0.079 12.5 0.2 0.26 10.9 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 ABK75397.1 - 0.09 12.6 0.0 0.41 10.5 0.0 2.2 1 1 0 1 1 1 0 Homeodomain-like domain HTH_10 PF04967.12 ABK75397.1 - 0.1 12.4 0.9 0.5 10.2 0.1 2.3 2 0 0 2 2 2 0 HTH DNA binding domain DUF3071 PF11268.8 ABK75397.1 - 0.15 12.1 1.2 0.17 11.9 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3071) BPD_transp_1 PF00528.22 ABK75398.1 - 3.2e-14 53.1 21.3 3.2e-14 53.1 21.3 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Gln-synt_C PF00120.24 ABK75399.1 - 1.7e-74 250.9 0.0 2.4e-74 250.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 ABK75399.1 - 0.0026 17.4 0.0 0.0092 15.7 0.0 1.9 2 0 0 2 2 2 1 Glutamine synthetase, beta-Grasp domain Glyco_hydro_114 PF03537.13 ABK75399.1 - 0.19 11.0 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 AGTRAP PF06396.11 ABK75400.1 - 0.28 11.0 1.4 0.78 9.5 1.4 1.8 1 0 0 1 1 1 0 Angiotensin II, type I receptor-associated protein (AGTRAP) Abhydrolase_6 PF12697.7 ABK75401.1 - 2.6e-18 67.4 17.5 4.1e-18 66.8 17.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK75401.1 - 3.8e-14 52.5 0.0 4.6e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ABK75401.1 - 5.6e-09 36.0 0.2 1.1e-08 35.0 0.2 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 ABK75401.1 - 0.0044 16.9 1.6 0.006 16.5 1.6 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 ABK75401.1 - 0.007 16.5 1.1 0.0075 16.4 0.1 1.6 2 0 0 2 2 2 1 Thioesterase domain Peptidase_S9 PF00326.21 ABK75401.1 - 0.011 15.2 0.0 0.025 14.0 0.0 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family TetR_N PF00440.23 ABK75403.1 - 1.4e-09 37.5 0.1 3.2e-09 36.4 0.0 1.6 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family Globin PF00042.22 ABK75404.1 - 1.8e-08 34.9 0.0 3.3e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Globin NAD_binding_1 PF00175.21 ABK75404.1 - 1.8e-07 31.8 0.0 4.2e-07 30.6 0.0 1.6 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Protoglobin PF11563.8 ABK75404.1 - 0.0003 20.7 0.0 0.00061 19.7 0.0 1.5 1 0 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.12 ABK75404.1 - 0.0037 17.4 0.1 0.0076 16.4 0.0 1.5 2 0 0 2 2 2 1 Ferric reductase NAD binding domain NAD_binding_9 PF13454.6 ABK75405.1 - 1.5e-06 28.2 1.6 5.8e-06 26.4 0.9 2.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 ABK75405.1 - 2.2e-06 27.1 0.0 4.1e-05 23.0 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ABK75405.1 - 4.8e-05 22.8 0.1 0.00031 20.1 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 ABK75406.1 - 4.8e-38 131.0 50.8 4.8e-38 131.0 50.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Citrate_synt PF00285.21 ABK75407.1 - 2e-83 280.5 0.3 1.8e-82 277.3 0.3 1.9 1 1 0 1 1 1 1 Citrate synthase, C-terminal domain Fe-ADH PF00465.19 ABK75407.1 - 0.088 11.6 1.9 0.17 10.7 0.3 1.9 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase MHB PF16525.5 ABK75408.1 - 1.3e-34 118.2 0.0 1.7e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Haemophore, haem-binding DUF4185 PF13810.6 ABK75410.1 - 3.9e-67 226.7 0.8 4.5e-67 226.5 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) CbtB PF09489.10 ABK75412.1 - 6.5e-17 61.4 2.3 8.5e-17 61.0 2.3 1.2 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtB) Peripla_BP_2 PF01497.18 ABK75412.1 - 0.1 12.1 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein LGFP PF08310.11 ABK75413.1 - 2.9e-19 69.3 9.0 3e-17 62.9 2.0 4.4 4 0 0 4 4 4 2 LGFP repeat Amidase_2 PF01510.25 ABK75413.1 - 1.5e-15 57.8 0.0 2.6e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase Chorismate_bind PF00425.18 ABK75414.1 - 1.5e-64 218.1 0.0 2.2e-64 217.5 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme PepSY_2 PF13670.6 ABK75415.1 - 0.00064 19.7 0.9 0.00085 19.3 0.9 1.2 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain FlgO PF17680.1 ABK75415.1 - 0.052 13.3 0.0 0.07 12.9 0.0 1.2 1 0 0 1 1 1 0 FlgO protein S_layer_N PF05123.12 ABK75415.1 - 0.098 12.5 2.2 0.13 12.2 2.2 1.1 1 0 0 1 1 1 0 S-layer like family, N-terminal region Ribosomal_L30 PF00327.20 ABK75416.1 - 5.7e-19 67.7 0.8 6.4e-19 67.6 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e RNase_T PF00929.24 ABK75417.1 - 4.3e-31 108.7 0.0 5.1e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Exonuclease PfkB PF00294.24 ABK75418.1 - 4.7e-15 55.7 0.1 6.6e-15 55.2 0.1 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 ABK75418.1 - 0.0018 17.7 0.0 0.0024 17.3 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Aminotran_3 PF00202.21 ABK75419.1 - 1.1e-88 297.7 0.0 1.3e-88 297.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 ABK75419.1 - 0.00039 19.7 0.0 0.00075 18.8 0.0 1.5 1 1 1 2 2 2 1 Aminotransferase class I and II Ribosomal_L35p PF01632.19 ABK75420.1 - 1.2e-24 86.6 7.5 1.3e-24 86.5 7.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L35 MFS_1 PF07690.16 ABK75421.1 - 9.9e-49 166.1 60.2 9.6e-40 136.6 34.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK75421.1 - 5.8e-15 55.1 5.5 5.8e-15 55.1 5.5 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 ABK75421.1 - 2.6e-07 30.3 8.8 2.6e-07 30.3 8.8 2.7 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB Ribosomal_S8 PF00410.19 ABK75423.1 - 1.2e-49 167.5 0.0 1.3e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S8 AMP-binding PF00501.28 ABK75424.1 - 3.7e-65 220.2 1.2 1.2e-45 155.9 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 ABK75424.1 - 2.3e-12 47.7 0.9 7e-12 46.2 0.1 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GntR PF00392.21 ABK75425.1 - 1.8e-15 56.3 0.8 3.6e-15 55.4 0.2 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family FCD PF07729.12 ABK75425.1 - 6.4e-14 52.4 10.4 1e-13 51.8 10.4 1.3 1 0 0 1 1 1 1 FCD domain TFIIE_alpha PF02002.17 ABK75425.1 - 0.035 13.9 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 TFIIE alpha subunit TrmB PF01978.19 ABK75425.1 - 0.041 13.8 0.1 0.34 10.8 0.0 2.1 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Carboxyl_trans PF01039.22 ABK75426.1 - 1.8e-124 416.1 0.1 2.3e-124 415.8 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 ABK75426.1 - 2.9e-07 30.2 6.7 3.5e-05 23.4 0.1 3.0 2 1 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) Glutaredoxin PF00462.24 ABK75427.1 - 3.8e-11 43.0 0.0 4.9e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 ABK75427.1 - 0.0034 17.7 0.0 0.0042 17.5 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF836 PF05768.14 ABK75427.1 - 0.0036 17.7 0.0 0.0037 17.6 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 ABK75427.1 - 0.0069 16.8 0.1 0.035 14.5 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.20 ABK75427.1 - 0.012 15.6 0.1 0.018 15.0 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin HCBP_related PF06594.11 ABK75427.1 - 0.08 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Haemolysin-type calcium binding protein related domain GST_N_2 PF13409.6 ABK75427.1 - 0.12 12.7 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_7 PF13899.6 ABK75427.1 - 0.13 12.4 0.0 0.28 11.4 0.0 1.8 1 1 1 2 2 2 0 Thioredoxin-like RibD_C PF01872.17 ABK75430.1 - 1.2e-13 51.3 0.0 2.4e-11 43.8 0.0 2.1 1 1 0 1 1 1 1 RibD C-terminal domain MFS_1 PF07690.16 ABK75431.1 - 4.4e-45 154.1 75.7 4.8e-36 124.4 52.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK75431.1 - 0.0034 16.3 18.0 0.0034 16.3 18.0 2.8 2 2 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.20 ABK75431.1 - 4.9 5.3 8.1 0.15 10.3 0.3 2.1 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Acyl_transf_3 PF01757.22 ABK75432.1 - 5.6e-27 94.7 35.8 8.1e-27 94.2 35.8 1.2 1 0 0 1 1 1 1 Acyltransferase family DUF2981 PF11200.8 ABK75432.1 - 0.055 13.2 1.5 0.093 12.5 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) PufQ PF05398.11 ABK75432.1 - 0.16 12.1 0.1 0.16 12.1 0.1 3.0 3 0 0 3 3 3 0 PufQ cytochrome subunit ADH_zinc_N PF00107.26 ABK75433.1 - 9.3e-28 96.8 0.2 1.4e-27 96.2 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ABK75433.1 - 5.4e-25 87.4 1.0 6.5e-25 87.1 0.1 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 ABK75433.1 - 4.1e-10 39.5 0.1 6.1e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 ABK75433.1 - 6e-08 33.8 0.1 1.1e-07 33.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ABK75433.1 - 0.0022 17.3 1.4 0.0034 16.7 1.4 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain PALP PF00291.25 ABK75433.1 - 0.0042 16.5 0.5 0.0063 16.0 0.5 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Met_10 PF02475.16 ABK75433.1 - 0.013 15.3 0.3 0.027 14.2 0.2 1.5 1 1 1 2 2 2 0 Met-10+ like-protein ELFV_dehydrog PF00208.21 ABK75433.1 - 0.031 14.0 0.1 0.046 13.4 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase FAD_binding_2 PF00890.24 ABK75433.1 - 0.14 11.2 2.0 0.44 9.6 0.9 1.9 2 0 0 2 2 2 0 FAD binding domain HEV_ORF1 PF02444.16 ABK75433.1 - 0.25 11.9 3.7 0.12 13.0 1.1 1.8 2 0 0 2 2 2 0 Hepatitis E virus ORF-2 (Putative capsid protein) ABC_tran PF00005.27 ABK75434.1 - 6.1e-50 169.3 0.0 4.7e-27 95.2 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ABK75434.1 - 5.2e-12 46.2 0.1 0.00093 19.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK75434.1 - 4.1e-05 23.1 0.1 0.0051 16.3 0.1 3.0 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ABK75434.1 - 0.00019 21.1 0.4 0.00047 19.9 0.0 1.8 2 0 0 2 2 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 ABK75434.1 - 0.00024 20.9 6.2 0.0012 18.6 0.4 3.6 3 2 0 3 3 2 1 AAA domain AAA_22 PF13401.6 ABK75434.1 - 0.00038 20.7 2.7 0.59 10.4 0.0 3.8 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.6 ABK75434.1 - 0.00051 20.5 1.7 0.85 10.0 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 ABK75434.1 - 0.00073 19.5 0.3 0.0036 17.2 0.0 2.2 3 0 0 3 3 2 1 RsgA GTPase AAA_23 PF13476.6 ABK75434.1 - 0.0026 18.3 0.0 0.0042 17.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 ABK75434.1 - 0.0032 17.5 0.0 0.044 13.9 0.0 2.6 3 0 0 3 3 3 1 50S ribosome-binding GTPase TsaE PF02367.17 ABK75434.1 - 0.0038 17.2 0.4 1.1 9.2 0.1 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 ABK75434.1 - 0.027 14.0 0.6 0.75 9.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_27 PF13514.6 ABK75434.1 - 0.029 14.0 0.0 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 ABK75434.1 - 0.051 12.4 1.7 0.096 11.5 0.2 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class SbcCD_C PF13558.6 ABK75434.1 - 0.061 13.6 0.1 1.9 8.8 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 ABK75434.1 - 0.096 12.4 0.1 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 ABK75434.1 - 0.1 12.6 0.0 0.56 10.3 0.0 2.1 2 0 0 2 2 2 0 Dynamin family DUF815 PF05673.13 ABK75434.1 - 0.14 11.3 0.1 0.42 9.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 ABK75434.1 - 0.14 11.4 0.2 3.2 7.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.29 ABK75434.1 - 0.17 12.3 1.0 5.5 7.4 0.1 3.4 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 ABK75434.1 - 0.19 12.3 0.5 30 5.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 ABK75434.1 - 0.34 9.8 2.7 13 4.7 0.1 3.1 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Ferritin PF00210.24 ABK75435.1 - 4.1e-26 91.6 0.0 5.2e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Ferritin-like domain Bac_luciferase PF00296.20 ABK75436.1 - 9.2e-17 61.4 0.3 8.3e-15 55.0 0.3 2.0 1 1 0 1 1 1 1 Luciferase-like monooxygenase 4HBT_3 PF13622.6 ABK75437.1 - 1.6e-43 149.8 3.7 1.8e-43 149.6 3.7 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 ABK75437.1 - 0.056 13.8 0.0 0.24 11.8 0.0 2.0 2 0 0 2 2 2 0 Thioesterase superfamily ATP-synt PF00231.19 ABK75438.1 - 1.6e-91 306.9 0.0 1.8e-91 306.7 0.0 1.0 1 0 0 1 1 1 1 ATP synthase CbiJ PF02571.14 ABK75438.1 - 0.00011 21.8 0.0 0.00019 21.0 0.0 1.3 1 0 0 1 1 1 1 Precorrin-6x reductase CbiJ/CobK MLTR_LBD PF17765.1 ABK75438.1 - 0.21 11.7 3.5 0.29 11.2 0.0 2.6 2 1 1 3 3 3 0 MmyB-like transcription regulator ligand binding domain Polyketide_cyc2 PF10604.9 ABK75439.1 - 5e-25 88.4 0.3 5.6e-25 88.3 0.3 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 ABK75439.1 - 1.9e-05 24.9 0.0 2.9e-05 24.3 0.0 1.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Sacchrp_dh_C PF16653.5 ABK75440.1 - 1.1e-21 78.2 0.0 1.3e-21 77.9 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 ABK75440.1 - 1.7e-18 67.2 0.0 2.5e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 ABK75440.1 - 0.0047 16.4 0.5 0.0076 15.7 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 ABK75440.1 - 0.0056 16.2 0.1 0.0085 15.6 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GFO_IDH_MocA PF01408.22 ABK75440.1 - 0.0069 17.2 0.1 0.012 16.4 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.18 ABK75440.1 - 0.0081 16.4 0.1 0.014 15.7 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain Ldh_1_N PF00056.23 ABK75440.1 - 0.0089 16.1 0.1 0.015 15.4 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain ThiF PF00899.21 ABK75440.1 - 0.012 15.0 0.3 0.02 14.2 0.3 1.5 1 1 0 1 1 1 0 ThiF family Polysacc_synt_2 PF02719.15 ABK75440.1 - 0.014 14.5 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GARS_N PF02844.15 ABK75440.1 - 0.032 15.0 0.0 0.065 14.0 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain F420_oxidored PF03807.17 ABK75440.1 - 0.067 13.8 0.1 0.12 12.9 0.1 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent PglD_N PF17836.1 ABK75440.1 - 0.13 12.9 0.0 0.24 12.1 0.0 1.4 1 0 0 1 1 1 0 PglD N-terminal domain UDPG_MGDP_dh_N PF03721.14 ABK75440.1 - 0.17 11.4 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF3180 PF11377.8 ABK75441.1 - 1.4e-42 145.1 18.7 1.6e-42 144.9 18.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3180) DUF4131 PF13567.6 ABK75441.1 - 0.057 13.1 6.0 1.6 8.4 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) LUD_dom PF02589.15 ABK75442.1 - 1.3e-49 168.5 0.0 2e-49 167.9 0.0 1.3 1 0 0 1 1 1 1 LUD domain Fer4_8 PF13183.6 ABK75442.1 - 1.1e-08 35.4 1.1 4.3e-08 33.5 1.3 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain DUF3390 PF11870.8 ABK75442.1 - 6.9e-08 32.8 0.8 1.4e-07 31.7 0.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3390) Fer4_7 PF12838.7 ABK75442.1 - 2.1e-05 25.0 3.5 6.7e-05 23.4 3.5 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 ABK75442.1 - 2.4e-05 24.4 0.8 0.042 14.0 0.1 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 ABK75442.1 - 3.8e-05 23.7 6.3 0.0018 18.3 8.0 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 ABK75442.1 - 4.8e-05 23.0 11.2 0.03 14.1 2.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 ABK75442.1 - 0.00012 22.6 1.6 0.0004 20.9 1.6 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_3 PF12798.7 ABK75442.1 - 0.00031 21.5 12.8 0.081 13.9 1.1 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.6 ABK75442.1 - 0.0024 18.1 2.3 0.45 10.7 0.3 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 ABK75442.1 - 0.006 16.6 12.8 0.017 15.2 3.6 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 ABK75442.1 - 0.0083 16.2 10.8 0.42 10.8 3.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 ABK75442.1 - 0.045 13.9 6.6 0.1 12.7 1.0 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_20 PF14691.6 ABK75442.1 - 0.045 13.5 2.5 1.1 9.0 0.1 2.3 2 0 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_16 PF13484.6 ABK75442.1 - 0.074 14.0 10.9 2.1 9.4 11.2 2.4 1 1 1 2 2 2 0 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 ABK75442.1 - 0.14 12.7 8.6 0.62 10.7 1.6 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_13 PF13370.6 ABK75442.1 - 3.1 8.4 6.8 22 5.7 6.8 2.1 1 1 0 1 1 1 0 4Fe-4S single cluster domain of Ferredoxin I ABC_tran PF00005.27 ABK75444.1 - 1.4e-33 116.3 0.0 2e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK75444.1 - 4.8e-12 46.3 0.1 1.6e-05 24.9 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ABK75444.1 - 3e-06 27.9 0.1 5.7e-06 27.0 0.1 1.4 2 0 0 2 2 1 1 AAA domain SMC_N PF02463.19 ABK75444.1 - 5.1e-06 26.1 0.0 0.00076 19.0 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 ABK75444.1 - 3.2e-05 23.8 0.0 7.4e-05 22.6 0.0 1.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 ABK75444.1 - 3.8e-05 23.3 0.0 7.5e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATPase_2 PF01637.18 ABK75444.1 - 0.00099 19.1 0.0 0.0016 18.4 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea ABC_ATPase PF09818.9 ABK75444.1 - 0.0015 17.4 0.0 0.031 13.1 0.0 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 ABK75444.1 - 0.0022 17.9 0.0 0.0038 17.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_27 PF13514.6 ABK75444.1 - 0.0041 16.7 0.0 0.0077 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ABK75444.1 - 0.0049 17.2 0.1 0.017 15.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 ABK75444.1 - 0.0069 16.8 0.0 0.012 16.0 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Adeno_IVa2 PF02456.15 ABK75444.1 - 0.012 14.5 0.0 0.016 14.0 0.0 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein ATP-synt_ab PF00006.25 ABK75444.1 - 0.012 15.2 0.1 0.064 12.9 0.0 1.9 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_16 PF13191.6 ABK75444.1 - 0.016 15.6 0.1 0.041 14.3 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 ABK75444.1 - 0.024 14.6 0.1 0.046 13.6 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 ABK75444.1 - 0.029 14.1 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 ABK75444.1 - 0.052 13.5 0.0 0.081 12.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain RNA_helicase PF00910.22 ABK75444.1 - 0.058 13.8 0.0 0.09 13.2 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 ABK75444.1 - 0.077 13.0 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ABK75444.1 - 0.08 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ABK75444.1 - 0.092 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Mg_chelatase PF01078.21 ABK75444.1 - 0.14 11.6 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 ABK75444.1 - 0.15 11.6 0.5 0.39 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 ABK75444.1 - 0.18 12.0 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 ABK75444.1 - 0.19 10.9 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DDE_3 PF13358.6 ABK75445.1 - 3e-24 85.4 0.0 4.5e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 ABK75445.1 - 4e-15 56.2 6.4 1.6e-14 54.3 0.7 3.2 3 0 0 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.6 ABK75445.1 - 9e-14 51.2 3.6 3.2e-13 49.5 0.4 3.2 3 0 0 3 3 3 1 Winged helix-turn helix HTH_28 PF13518.6 ABK75445.1 - 1.5e-13 50.6 5.9 3.5e-11 43.1 0.4 3.1 3 0 0 3 3 2 2 Helix-turn-helix domain HTH_23 PF13384.6 ABK75445.1 - 1.5e-12 46.9 1.7 3.6e-09 36.1 0.4 3.2 2 1 1 3 3 3 2 Homeodomain-like domain HTH_50 PF18024.1 ABK75445.1 - 0.00034 20.2 0.2 0.0013 18.3 0.0 2.1 3 0 0 3 3 2 1 Helix-turn-helix domain HTH_24 PF13412.6 ABK75445.1 - 0.00071 19.1 0.1 0.039 13.5 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_6 PF01418.17 ABK75445.1 - 0.001 19.0 0.0 0.0036 17.2 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain, rpiR family HTH_IclR PF09339.10 ABK75445.1 - 0.0015 18.3 0.6 0.059 13.2 0.0 2.4 2 0 0 2 2 2 1 IclR helix-turn-helix domain YdaS_antitoxin PF15943.5 ABK75445.1 - 0.003 17.4 0.2 0.9 9.5 0.0 2.9 3 0 0 3 3 3 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Sigma70_r4_2 PF08281.12 ABK75445.1 - 0.0046 16.6 0.0 0.051 13.3 0.0 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_26 PF13443.6 ABK75445.1 - 0.0058 17.0 0.6 0.99 9.9 0.0 3.1 3 0 0 3 3 3 1 Cro/C1-type HTH DNA-binding domain HTH_Crp_2 PF13545.6 ABK75445.1 - 0.0068 16.4 0.1 2.6 8.1 0.0 2.5 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_AsnC-type PF13404.6 ABK75445.1 - 0.0089 15.8 0.1 0.64 9.9 0.0 2.5 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_37 PF13744.6 ABK75445.1 - 0.026 14.5 0.0 0.47 10.5 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.7 ABK75445.1 - 0.034 14.3 0.4 3.3 8.0 0.0 3.1 3 0 0 3 3 2 0 Helix-turn-helix domain MarR PF01047.22 ABK75445.1 - 0.044 13.7 0.0 12 5.9 0.0 2.5 2 0 0 2 2 2 0 MarR family HTH_36 PF13730.6 ABK75445.1 - 0.044 13.7 0.0 0.34 10.9 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 ABK75445.1 - 0.048 14.2 1.5 0.056 14.0 0.1 1.8 2 0 0 2 2 1 0 leucine-zipper of insertion element IS481 HTH_Tnp_ISL3 PF13542.6 ABK75445.1 - 0.049 13.0 4.2 0.054 12.9 0.7 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4 PF04545.16 ABK75445.1 - 0.056 13.0 0.1 3.2 7.3 0.0 2.7 2 0 0 2 2 2 0 Sigma-70, region 4 GerE PF00196.19 ABK75445.1 - 0.084 12.4 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family DUF746 PF05344.11 ABK75445.1 - 0.13 12.1 0.8 2.5 8.0 0.0 3.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF746) HTH_3 PF01381.22 ABK75445.1 - 0.18 11.9 0.0 14 5.9 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix Metallophos PF00149.28 ABK75446.1 - 5.2e-11 43.4 0.1 1.1e-10 42.3 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1660 PF07874.11 ABK75447.1 - 6.5e-05 23.3 0.0 8.3e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Prophage protein (DUF1660) p450 PF00067.22 ABK75448.1 - 1.5e-23 83.3 0.0 9.1e-22 77.4 0.0 2.7 2 1 0 2 2 2 1 Cytochrome P450 HTH_3 PF01381.22 ABK75449.1 - 0.00021 21.3 0.0 0.00039 20.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_23 PF13384.6 ABK75449.1 - 0.00055 19.6 0.1 0.0011 18.7 0.1 1.4 1 0 0 1 1 1 1 Homeodomain-like domain YdaS_antitoxin PF15943.5 ABK75449.1 - 0.0014 18.4 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_11 PF08279.12 ABK75449.1 - 0.0074 16.2 0.2 0.068 13.1 0.1 2.3 2 1 1 3 3 3 1 HTH domain DUF1323 PF07037.11 ABK75449.1 - 0.0087 16.4 0.0 0.016 15.6 0.0 1.4 1 0 0 1 1 1 1 Putative transcription regulator (DUF1323) HTH_28 PF13518.6 ABK75449.1 - 0.012 15.7 0.2 0.026 14.7 0.2 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 ABK75449.1 - 0.028 14.4 0.0 0.047 13.7 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain KORA PF16509.5 ABK75449.1 - 0.11 12.8 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 TrfB plasmid transcriptional repressor Crp PF00325.20 ABK75449.1 - 0.15 11.7 0.1 0.29 10.8 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family Bac_luciferase PF00296.20 ABK75450.1 - 2.6e-35 122.4 7.1 2.6e-35 122.4 7.1 1.4 1 1 0 1 1 1 1 Luciferase-like monooxygenase HhH-GPD PF00730.25 ABK75451.1 - 2.5e-18 66.5 0.0 3.1e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Peptidase_M17_N PF02789.17 ABK75451.1 - 0.038 13.8 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain Polyketide_cyc PF03364.20 ABK75452.1 - 2.7e-15 56.7 0.0 3.1e-15 56.5 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 ABK75452.1 - 7.2e-11 42.5 0.0 8.9e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF2505 PF10698.9 ABK75452.1 - 0.051 13.7 0.2 0.15 12.2 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2505) DAO PF01266.24 ABK75454.1 - 4.1e-63 214.1 2.6 4.9e-63 213.8 2.6 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ABK75454.1 - 4.5e-07 29.4 0.1 0.0035 16.6 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ABK75454.1 - 2.3e-06 27.7 0.1 5.7e-06 26.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ABK75454.1 - 0.00017 21.6 0.6 0.11 12.5 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Amino_oxidase PF01593.24 ABK75454.1 - 0.00017 21.0 0.1 0.028 13.7 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase ApbA PF02558.16 ABK75454.1 - 0.00078 19.1 0.1 0.0018 17.9 0.1 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 ABK75454.1 - 0.0013 18.1 0.1 0.0093 15.2 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ABK75454.1 - 0.0017 17.7 1.8 0.0038 16.5 0.1 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 ABK75454.1 - 0.0025 18.1 0.3 0.009 16.3 0.1 2.1 2 0 0 2 2 2 1 TrkA-N domain 2-Hacid_dh_C PF02826.19 ABK75454.1 - 0.0083 15.5 0.1 0.013 14.9 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 ABK75454.1 - 0.01 16.3 0.0 0.045 14.3 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 ABK75454.1 - 0.038 14.2 0.4 0.075 13.3 0.4 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 ABK75454.1 - 0.082 12.5 0.2 0.14 11.7 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.14 ABK75454.1 - 0.098 11.3 0.1 2.4 6.8 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein 3HCDH_N PF02737.18 ABK75454.1 - 0.25 11.2 0.7 0.46 10.3 0.7 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 ABK75454.1 - 0.49 9.4 3.5 0.61 9.1 0.5 2.3 3 0 0 3 3 3 0 FAD binding domain NfeD PF01957.18 ABK75455.1 - 0.00022 21.5 0.0 0.00048 20.4 0.0 1.6 2 0 0 2 2 2 1 NfeD-like C-terminal, partner-binding p450 PF00067.22 ABK75456.1 - 3.8e-27 95.2 0.0 8.6e-25 87.4 0.0 2.7 2 1 0 2 2 2 1 Cytochrome P450 Methyltransf_33 PF10017.9 ABK75457.1 - 1e-114 382.9 0.0 1.2e-114 382.7 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_25 PF13649.6 ABK75457.1 - 0.01 16.5 0.0 0.039 14.7 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain DFP PF04127.15 ABK75458.1 - 3.2e-62 209.7 0.4 3.2e-62 209.7 0.4 2.0 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein Flavoprotein PF02441.19 ABK75458.1 - 6.4e-37 126.7 0.1 1.5e-36 125.6 0.0 1.6 2 0 0 2 2 2 1 Flavoprotein YjeF_N PF03853.15 ABK75458.1 - 0.00045 20.1 2.5 0.0084 16.0 0.1 2.5 2 0 0 2 2 2 1 YjeF-related protein N-terminus Nitro_FeMo-Co PF02579.17 ABK75458.1 - 0.021 15.2 0.2 10 6.5 0.0 2.9 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor Glyco_transf_4 PF13439.6 ABK75458.1 - 0.028 14.4 0.6 6 6.8 0.0 2.5 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Asp_Glu_race PF01177.22 ABK75458.1 - 0.074 12.9 0.9 5.2 6.8 0.2 2.7 2 1 1 3 3 3 0 Asp/Glu/Hydantoin racemase PspC PF04024.12 ABK75458.1 - 0.096 12.5 0.3 0.21 11.4 0.3 1.6 1 0 0 1 1 1 0 PspC domain Methyltransf_12 PF08242.12 ABK75459.1 - 6.1e-07 30.1 0.0 1.1e-06 29.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABK75459.1 - 2.1e-06 28.3 0.0 4.9e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABK75459.1 - 0.00098 19.7 0.0 0.0021 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 ABK75459.1 - 0.025 13.9 0.0 0.039 13.3 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain TetR_N PF00440.23 ABK75460.1 - 7.7e-12 44.8 1.8 1.3e-11 44.1 1.8 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 ABK75460.1 - 0.0003 21.1 0.9 0.0003 21.1 0.9 2.2 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain PknH_C PF14032.6 ABK75461.1 - 2.3e-47 161.3 3.9 2.9e-47 161.0 3.9 1.1 1 0 0 1 1 1 1 PknH-like extracellular domain AvrD PF05655.11 ABK75461.1 - 0.044 13.1 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 Pseudomonas avirulence D protein (AvrD) DUF2613 PF11021.8 ABK75461.1 - 0.13 12.4 1.0 0.29 11.3 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) TPPK_C PF12555.8 ABK75462.1 - 0.0023 17.9 0.4 0.0023 17.9 0.4 1.0 1 0 0 1 1 1 1 Thiamine pyrophosphokinase C terminal FeoB_associated PF12669.7 ABK75462.1 - 0.17 12.3 0.4 0.18 12.3 0.4 1.1 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Radical_SAM PF04055.21 ABK75463.1 - 1.2e-22 81.0 0.0 1.8e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily SPASM PF13186.6 ABK75463.1 - 1e-07 32.3 0.0 1.9e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Iron-sulfur cluster-binding domain Fer4_12 PF13353.6 ABK75463.1 - 8.6e-06 26.1 0.0 1.3e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 ABK75463.1 - 0.00035 20.7 0.0 0.00078 19.6 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain AP_endonuc_2 PF01261.24 ABK75463.1 - 0.075 12.5 0.2 0.42 10.0 0.2 2.0 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel DUF3716 PF12511.8 ABK75463.1 - 0.087 12.9 1.1 0.26 11.4 1.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) FGGY_N PF00370.21 ABK75464.1 - 1.4e-39 136.2 0.0 1.8e-39 135.7 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 ABK75464.1 - 8e-30 104.0 0.0 1.4e-29 103.3 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 ABK75464.1 - 0.0081 15.7 0.5 0.013 15.0 0.5 1.4 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family MutL PF13941.6 ABK75464.1 - 0.04 12.5 0.2 0.063 11.9 0.2 1.3 1 0 0 1 1 1 0 MutL protein AAA_16 PF13191.6 ABK75465.1 - 8e-16 58.9 0.1 8e-16 58.9 0.1 4.3 2 1 1 3 3 3 1 AAA ATPase domain GerE PF00196.19 ABK75465.1 - 4.3e-13 48.6 0.0 1.2e-12 47.2 0.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family AAA_22 PF13401.6 ABK75465.1 - 2.5e-07 31.1 0.0 1.4e-06 28.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain HTH_24 PF13412.6 ABK75465.1 - 0.00024 20.6 0.0 0.01 15.4 0.0 2.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Sigma70_r4_2 PF08281.12 ABK75465.1 - 0.00077 19.1 0.1 0.31 10.8 0.0 3.0 2 0 0 2 2 2 2 Sigma-70, region 4 HTH_38 PF13936.6 ABK75465.1 - 0.00084 19.1 0.1 0.0025 17.6 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 ABK75465.1 - 0.0022 17.8 1.8 0.074 12.9 0.1 3.5 2 0 0 2 2 2 1 Homeodomain-like domain NACHT PF05729.12 ABK75465.1 - 0.015 15.2 0.0 0.032 14.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 ABK75465.1 - 0.082 12.7 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain TPR_19 PF14559.6 ABK75465.1 - 4.6 7.8 26.5 0.11 13.1 0.5 6.1 5 1 1 6 6 6 0 Tetratricopeptide repeat MFS_3 PF05977.13 ABK75466.1 - 5.2e-53 180.2 35.4 5.8e-53 180.1 35.4 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.16 ABK75466.1 - 2.5e-29 102.3 50.6 5.2e-28 98.0 37.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ApoL PF05461.11 ABK75466.1 - 6.6 5.9 6.6 5.2 6.3 4.9 1.6 2 0 0 2 2 2 0 Apolipoprotein L Acyl_transf_1 PF00698.21 ABK75467.1 - 2.2e-52 178.6 0.5 3.3e-52 178.0 0.5 1.2 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 ABK75467.1 - 1.2e-31 110.0 0.2 2.9e-31 108.8 0.2 1.7 1 0 0 1 1 1 1 KR domain PP-binding PF00550.25 ABK75467.1 - 9.4e-10 38.7 0.7 2.6e-09 37.3 0.7 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 ABK75467.1 - 1.1e-09 38.1 0.2 4.2e-09 36.1 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.21 ABK75467.1 - 2.1e-07 30.7 0.1 1.2e-06 28.2 0.0 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ABK75467.1 - 0.00016 20.9 0.0 0.00025 20.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GRDA PF04723.14 ABK75467.1 - 0.053 13.3 0.4 0.18 11.5 0.1 2.0 2 0 0 2 2 2 0 Glycine reductase complex selenoprotein A RmlD_sub_bind PF04321.17 ABK75467.1 - 0.1 11.7 0.3 0.21 10.7 0.3 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain SBP_bac_1 PF01547.25 ABK75468.1 - 5.5e-46 158.0 2.3 7.2e-46 157.6 2.3 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 ABK75468.1 - 2e-25 90.1 0.1 2.6e-25 89.8 0.1 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Peptidase_M22 PF00814.25 ABK75469.1 - 8.3e-05 22.4 0.1 0.00012 21.8 0.1 1.2 1 0 0 1 1 1 1 Glycoprotease family Thiolase_N PF00108.23 ABK75469.1 - 0.0016 17.9 1.8 0.0027 17.1 0.4 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 ABK75469.1 - 0.02 14.8 0.1 3 7.8 0.0 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III MTS PF05175.14 ABK75470.1 - 1.8e-18 66.7 0.0 6.2e-18 64.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 ABK75470.1 - 7.3e-08 33.0 0.1 6.8e-07 29.9 0.1 2.7 2 1 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 ABK75470.1 - 1.1e-05 25.0 0.0 2.9e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 ABK75470.1 - 2.2e-05 25.0 0.0 0.00015 22.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABK75470.1 - 4e-05 23.5 0.0 7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABK75470.1 - 0.00017 21.4 0.0 0.00084 19.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK75470.1 - 0.0011 19.7 0.0 0.025 15.3 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain TehB PF03848.14 ABK75470.1 - 0.037 13.4 0.0 0.073 12.5 0.0 1.5 1 1 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_15 PF09445.10 ABK75470.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Aldolase PF01081.19 ABK75471.1 - 1.9e-68 229.8 0.0 2.1e-68 229.6 0.0 1.0 1 0 0 1 1 1 1 KDPG and KHG aldolase Putative_PNPOx PF01243.20 ABK75472.1 - 1e-11 44.8 0.5 1.6e-11 44.2 0.0 1.5 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 ABK75472.1 - 0.023 14.3 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like Pur_DNA_glyco PF02245.16 ABK75473.1 - 1.3e-56 190.8 0.0 1.5e-56 190.6 0.0 1.0 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) DUF1980 PF09323.10 ABK75474.1 - 1.4e-09 38.2 0.0 1.9e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1980) TctB PF07331.11 ABK75474.1 - 2.2e-05 24.7 0.2 3.9e-05 23.9 0.2 1.3 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family MerC PF03203.14 ABK75474.1 - 0.011 16.2 0.1 0.019 15.4 0.1 1.4 1 0 0 1 1 1 0 MerC mercury resistance protein DUF1616 PF07760.11 ABK75474.1 - 0.096 12.1 0.8 0.14 11.5 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1616) DUF979 PF06166.12 ABK75474.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF979) Peptidase_S9 PF00326.21 ABK75475.1 - 7.2e-43 146.5 0.5 9.8e-43 146.1 0.5 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 ABK75475.1 - 2e-06 26.7 0.0 6.5e-05 21.7 0.0 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 ABK75475.1 - 2.7e-05 24.0 3.2 0.0044 16.7 2.5 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ABK75475.1 - 8.9e-05 21.9 0.6 0.02 14.1 0.4 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Esterase_phd PF10503.9 ABK75475.1 - 0.00084 18.9 0.2 0.0028 17.2 0.2 1.8 1 1 0 1 1 1 1 Esterase PHB depolymerase PD40 PF07676.12 ABK75475.1 - 0.001 19.0 0.0 14 5.7 0.0 4.3 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat DLH PF01738.18 ABK75475.1 - 0.0011 18.5 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 Dienelactone hydrolase family SGL PF08450.12 ABK75475.1 - 0.042 13.4 0.0 8.8 5.8 0.0 2.7 2 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region Lactonase PF10282.9 ABK75475.1 - 0.065 12.5 0.0 0.58 9.4 0.0 2.1 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Ydr279_N PF17745.1 ABK75475.1 - 0.2 11.9 0.0 0.99 9.7 0.0 2.2 2 0 0 2 2 2 0 Ydr279p protein triple barrel domain DUF4235 PF14019.6 ABK75476.1 - 0.043 13.9 0.7 12 6.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) Phage_holin_5_2 PF16079.5 ABK75476.1 - 3 8.3 12.9 3.8 7.9 0.6 3.5 2 1 1 3 3 3 0 Phage holin family Hol44, in holin superfamily V Peptidase_M20 PF01546.28 ABK75477.1 - 4.8e-25 88.5 0.3 6.3e-25 88.1 0.3 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 ABK75477.1 - 0.0011 18.7 0.0 0.0015 18.2 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M28 rve PF00665.26 ABK75478.1 - 1.6e-12 47.6 0.2 1.3e-11 44.7 0.0 2.5 3 0 0 3 3 3 1 Integrase core domain HTH_38 PF13936.6 ABK75478.1 - 3.3e-05 23.5 0.0 6.8e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 ABK75478.1 - 0.0052 16.5 0.7 0.019 14.7 0.4 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 ABK75478.1 - 0.014 15.4 0.1 0.049 13.7 0.1 1.9 1 0 0 1 1 1 0 Winged helix-turn helix HTH_3 PF01381.22 ABK75478.1 - 0.015 15.3 0.0 0.035 14.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix HTH_35 PF13693.6 ABK75478.1 - 0.018 15.1 0.0 0.055 13.5 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_19 PF12844.7 ABK75478.1 - 0.022 14.7 0.0 0.049 13.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_31 PF13560.6 ABK75478.1 - 0.023 15.0 6.7 0.023 15.0 0.3 3.8 3 1 0 3 3 3 0 Helix-turn-helix domain HTH_39 PF14090.6 ABK75478.1 - 0.16 11.8 0.6 1.7 8.4 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain IGPD PF00475.18 ABK75479.1 - 1.5e-57 194.0 0.5 2.2e-57 193.4 0.5 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Aldedh PF00171.22 ABK75481.1 - 4.7e-132 440.8 0.2 5.6e-132 440.5 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Mito_fiss_Elm1 PF06258.11 ABK75481.1 - 0.038 13.1 0.0 0.062 12.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial fission ELM1 Tim17 PF02466.19 ABK75481.1 - 0.062 13.7 0.8 0.56 10.6 0.0 2.4 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family TauD PF02668.16 ABK75482.1 - 1.5e-49 169.2 0.7 1.9e-49 168.9 0.7 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF3880 PF12996.7 ABK75482.1 - 0.13 12.3 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 DUF based on E. rectale Gene description (DUF3880) FAD_binding_5 PF00941.21 ABK75483.1 - 8.2e-41 139.6 0.0 1.4e-40 138.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 ABK75483.1 - 1e-20 73.8 0.5 2.1e-20 72.8 0.5 1.5 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain EI24 PF07264.11 ABK75484.1 - 0.29 11.4 4.0 0.89 9.8 4.0 1.6 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) E2_bind PF08825.10 ABK75485.1 - 0.078 13.1 0.0 14 5.9 0.0 2.2 2 0 0 2 2 2 0 E2 binding domain DUF5455 PF17537.2 ABK75486.1 - 0.018 15.5 0.2 0.023 15.1 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5455) Peptidase_S66 PF02016.15 ABK75486.1 - 0.043 13.9 0.0 0.053 13.6 0.0 1.2 1 0 0 1 1 1 0 LD-carboxypeptidase N-terminal domain TraT PF05818.12 ABK75486.1 - 0.47 10.1 4.4 0.79 9.4 0.1 2.6 1 1 2 3 3 3 0 Enterobacterial TraT complement resistance protein GTP_EFTU PF00009.27 ABK75487.1 - 6.8e-51 172.6 0.6 9.3e-51 172.1 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 ABK75487.1 - 2.4e-24 85.2 0.0 5e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ABK75487.1 - 4.4e-14 52.6 0.6 1.6e-13 50.8 0.6 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ABK75487.1 - 1.8e-06 28.0 0.1 4.2e-06 26.8 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 ABK75487.1 - 0.011 15.0 0.1 0.018 14.3 0.1 1.2 1 0 0 1 1 1 0 Septin Pribosyltran PF00156.27 ABK75488.1 - 3.6e-20 72.1 0.3 4.5e-20 71.8 0.3 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 ABK75488.1 - 0.0019 17.7 0.0 0.003 17.0 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase ATP_bind_1 PF03029.17 ABK75489.1 - 1.7e-29 103.3 0.2 1.8e-27 96.7 0.2 2.8 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 ABK75489.1 - 0.00061 19.4 0.0 0.0008 19.0 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain T2SSE PF00437.20 ABK75489.1 - 0.0037 16.4 0.1 0.0049 16.0 0.1 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein Ras PF00071.22 ABK75489.1 - 0.014 15.0 0.1 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 Ras family TsaE PF02367.17 ABK75489.1 - 0.021 14.8 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 ABK75489.1 - 0.04 13.7 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 ABK75489.1 - 0.05 14.0 0.0 0.08 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 ABK75489.1 - 0.056 13.2 0.1 0.081 12.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ABK75489.1 - 0.07 13.4 0.1 0.1 12.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 ABK75489.1 - 0.23 11.4 0.4 0.66 9.9 0.1 1.8 2 0 0 2 2 2 0 NTPase DUF2017 PF09438.10 ABK75490.1 - 1.1e-58 198.0 0.1 1.2e-58 197.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2017) FAD_binding_3 PF01494.19 ABK75492.1 - 9.7e-61 205.9 0.0 1.2e-60 205.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain TrkA_N PF02254.18 ABK75492.1 - 0.00037 20.7 0.1 0.0012 19.1 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_9 PF13454.6 ABK75492.1 - 0.0011 19.0 0.0 0.0062 16.5 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 ABK75492.1 - 0.0024 17.5 0.1 0.0046 16.5 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 ABK75492.1 - 0.0026 17.4 0.0 0.0049 16.5 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 ABK75492.1 - 0.0059 15.9 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ABK75492.1 - 0.025 13.9 0.6 0.22 10.9 0.6 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase F420_oxidored PF03807.17 ABK75492.1 - 0.027 15.0 0.0 0.074 13.6 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.24 ABK75492.1 - 0.029 13.9 4.0 0.083 12.5 0.3 2.6 1 1 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 ABK75492.1 - 0.045 12.5 0.0 0.065 11.9 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.18 ABK75492.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 ABK75492.1 - 0.19 10.8 0.7 2 7.4 0.0 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein CBM_48 PF02922.18 ABK75494.1 - 2.8e-20 72.5 0.0 5.4e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 ABK75494.1 - 2.6e-15 56.8 0.0 1.2e-08 35.0 0.0 2.6 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 ABK75494.1 - 0.068 11.4 0.0 0.099 10.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 hDGE_amylase PF14701.6 ABK75494.1 - 0.16 11.0 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Rubredoxin PF00301.20 ABK75495.1 - 1e-22 79.9 5.1 1.1e-22 79.7 5.1 1.0 1 0 0 1 1 1 1 Rubredoxin OrfB_Zn_ribbon PF07282.11 ABK75495.1 - 0.0047 16.8 0.3 0.98 9.4 0.1 2.1 2 0 0 2 2 2 2 Putative transposase DNA-binding domain Rubredoxin_2 PF18073.1 ABK75495.1 - 0.012 15.3 7.3 0.14 12.0 0.4 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain zinc_ribbon_10 PF10058.9 ABK75495.1 - 0.026 14.2 0.6 1.2 8.9 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf_UBZ PF18439.1 ABK75495.1 - 0.031 13.9 0.7 2.2 7.9 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Zn_ribbon_SprT PF17283.2 ABK75495.1 - 0.034 14.1 1.0 3.3 7.7 0.1 2.2 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zinc_ribbon_2 PF13240.6 ABK75495.1 - 0.046 13.4 0.8 4.4 7.2 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 ABK75495.1 - 0.046 13.1 0.9 1.1 8.8 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain HypA PF01155.19 ABK75495.1 - 0.049 13.7 0.1 0.058 13.4 0.1 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 ABK75495.1 - 0.077 13.1 4.2 0.45 10.7 4.2 1.9 1 1 0 1 1 1 0 Zinc ribbon domain zf-RanBP PF00641.18 ABK75495.1 - 0.099 12.0 3.8 0.99 8.8 0.5 2.2 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-HYPF PF07503.12 ABK75495.1 - 0.1 12.4 0.8 7.3 6.5 0.1 2.2 2 0 0 2 2 2 0 HypF finger zf_C2H2_ZHX PF18387.1 ABK75495.1 - 0.18 11.4 0.6 0.82 9.4 0.1 1.9 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain PHD_4 PF16866.5 ABK75495.1 - 1.4 9.1 6.5 3.7 7.7 6.5 1.7 1 1 0 1 1 1 0 PHD-finger LytR_cpsA_psr PF03816.14 ABK75496.1 - 6e-32 110.9 0.0 9.1e-32 110.3 0.0 1.3 1 0 0 1 1 1 1 Cell envelope-related transcriptional attenuator domain LytR_C PF13399.6 ABK75496.1 - 1e-13 52.0 1.6 5.6e-13 49.7 0.5 2.5 2 0 0 2 2 2 1 LytR cell envelope-related transcriptional attenuator Lumazine_bd_2 PF12893.7 ABK75496.1 - 0.14 12.8 0.1 0.63 10.7 0.1 2.1 2 0 0 2 2 2 0 Putative lumazine-binding adh_short_C2 PF13561.6 ABK75497.1 - 1.3e-63 214.7 0.5 1.7e-63 214.4 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK75497.1 - 1.9e-48 164.5 1.4 2.2e-48 164.3 1.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK75497.1 - 4.1e-07 30.1 1.0 7.3e-07 29.3 0.9 1.4 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 ABK75497.1 - 7e-07 29.6 0.6 1.1e-06 28.9 0.6 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 ABK75497.1 - 0.0002 20.9 0.5 0.00048 19.7 0.5 1.7 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ABK75497.1 - 0.019 14.1 0.1 0.039 13.1 0.1 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DFP PF04127.15 ABK75497.1 - 0.024 14.5 2.1 0.063 13.1 2.1 1.6 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein 3HCDH_N PF02737.18 ABK75497.1 - 0.055 13.4 1.9 0.079 12.8 1.9 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 ABK75497.1 - 0.11 12.6 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase IclR PF01614.18 ABK75498.1 - 1.6e-22 79.7 0.2 2.5e-22 79.1 0.2 1.3 1 0 0 1 1 1 1 Bacterial transcriptional regulator HTH_IclR PF09339.10 ABK75498.1 - 6.8e-14 51.4 3.4 7.4e-14 51.3 2.2 1.8 2 0 0 2 2 2 1 IclR helix-turn-helix domain MarR_2 PF12802.7 ABK75498.1 - 3.9e-05 23.5 0.3 0.00012 21.9 0.3 1.8 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 ABK75498.1 - 5.2e-05 22.7 0.0 0.00011 21.6 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 ABK75498.1 - 0.00084 19.2 0.1 0.0014 18.5 0.1 1.3 1 0 0 1 1 1 1 MarR family HTH_AsnC-type PF13404.6 ABK75498.1 - 0.0026 17.6 0.3 0.0026 17.6 0.3 2.8 3 0 0 3 3 3 1 AsnC-type helix-turn-helix domain Rrf2 PF02082.20 ABK75498.1 - 0.013 15.8 0.2 0.036 14.4 0.1 1.7 2 0 0 2 2 2 0 Transcriptional regulator FeoC PF09012.10 ABK75498.1 - 0.028 14.5 0.1 0.076 13.1 0.0 1.7 2 0 0 2 2 2 0 FeoC like transcriptional regulator HTH_5 PF01022.20 ABK75498.1 - 0.039 13.8 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 ABK75498.1 - 0.054 13.6 2.1 0.072 13.2 0.5 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_27 PF13463.6 ABK75498.1 - 0.079 13.5 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain GT87 PF09594.10 ABK75499.1 - 3.4e-54 184.1 30.1 3.4e-54 184.1 30.1 2.2 2 0 0 2 2 2 1 Glycosyltransferase family 87 Peptidase_M1 PF01433.20 ABK75500.1 - 4.1e-25 88.7 0.5 7.8e-25 87.7 0.5 1.5 1 1 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 ABK75500.1 - 4.7e-13 49.7 0.0 7.8e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 ABK75500.1 - 0.054 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase MA superfamily Peptidase_M61 PF05299.12 ABK75500.1 - 0.5 10.8 2.9 14 6.1 2.9 2.4 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Polysacc_deac_1 PF01522.21 ABK75501.1 - 5.8e-18 65.0 0.0 9.2e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 ABK75501.1 - 0.0012 18.6 0.0 0.0021 17.8 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_trans_4_4 PF13579.6 ABK75501.1 - 0.7 10.3 7.7 14 6.1 7.7 2.6 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain LpqV PF17301.2 ABK75502.1 - 1e-49 167.5 7.6 1.4e-49 167.1 7.6 1.2 1 0 0 1 1 1 1 Putative lipoprotein LpqV LYTB PF02401.18 ABK75503.1 - 3.1e-90 302.0 0.1 3.5e-90 301.8 0.1 1.0 1 0 0 1 1 1 1 LytB protein CoA_binding_2 PF13380.6 ABK75503.1 - 0.55 10.7 4.5 3.4 8.2 0.3 3.7 1 1 1 2 2 2 0 CoA binding domain adh_short PF00106.25 ABK75504.1 - 1.6e-52 177.8 1.8 2e-52 177.5 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK75504.1 - 6.8e-43 146.9 2.1 8.7e-43 146.5 2.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK75504.1 - 3.8e-15 56.2 1.3 5e-15 55.9 1.3 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 ABK75504.1 - 0.0021 17.4 1.4 0.0058 16.0 1.2 1.9 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 ABK75504.1 - 0.0097 15.4 2.8 0.0099 15.4 1.0 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family HEM4 PF02602.15 ABK75504.1 - 0.029 13.7 0.3 0.38 10.1 0.3 2.2 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD GntR PF00392.21 ABK75505.1 - 6.7e-16 57.7 0.4 1.5e-15 56.6 0.4 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Aminotran_1_2 PF00155.21 ABK75505.1 - 7.7e-15 54.9 0.0 1e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II HTH_Crp_2 PF13545.6 ABK75505.1 - 0.016 15.1 0.0 0.055 13.4 0.0 1.9 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain FANC_SAP PF18081.1 ABK75505.1 - 0.29 11.3 7.4 0.36 11.0 2.2 3.2 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain SpoU_methylase PF00588.19 ABK75506.1 - 2e-36 125.3 0.1 3.2e-36 124.6 0.1 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 ABK75506.1 - 1.8e-16 60.2 0.0 2.9e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding CPBP PF02517.16 ABK75508.1 - 3.2e-16 59.5 2.2 3.2e-16 59.5 2.2 2.6 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease Cpn60_TCP1 PF00118.24 ABK75509.1 - 2.8e-83 280.2 7.1 5.4e-83 279.3 7.1 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family HATPase_c PF02518.26 ABK75510.1 - 4.2e-21 75.5 0.0 7.4e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 ABK75510.1 - 1.3e-12 47.9 2.4 3.4e-12 46.5 2.4 1.8 1 0 0 1 1 1 1 HAMP domain HisKA PF00512.25 ABK75510.1 - 6.2e-12 45.4 0.8 1.6e-11 44.0 0.2 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 ABK75510.1 - 0.033 14.2 0.0 0.1 12.6 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain FtsL PF04999.13 ABK75510.1 - 0.065 13.2 0.2 0.14 12.1 0.2 1.5 1 0 0 1 1 1 0 Cell division protein FtsL HATPase_c_3 PF13589.6 ABK75510.1 - 0.18 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF402 PF04167.13 ABK75511.1 - 1e-17 64.1 1.5 2.8e-17 62.7 0.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF402) DAGK_cat PF00781.24 ABK75512.1 - 4.7e-31 107.0 0.4 9e-31 106.1 0.4 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 ABK75512.1 - 7e-05 22.2 0.4 0.0001 21.6 0.4 1.2 1 0 0 1 1 1 1 ATP-NAD kinase BPD_transp_1 PF00528.22 ABK75513.1 - 2.7e-22 79.4 14.5 4.9e-22 78.6 14.5 1.4 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component DUF5078 PF16877.5 ABK75514.1 - 0.023 15.1 0.3 0.16 12.5 0.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF5078) DUF2344 PF10105.9 ABK75514.1 - 0.14 12.0 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) PknH_C PF14032.6 ABK75515.1 - 1.8e-36 125.8 5.9 2.1e-36 125.6 5.9 1.1 1 0 0 1 1 1 1 PknH-like extracellular domain Glyco_hydro_3 PF00933.21 ABK75516.1 - 4.2e-51 174.2 0.0 8e-51 173.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 ABK75516.1 - 7.5e-51 173.0 0.0 1.1e-50 172.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 ABK75516.1 - 1.3e-22 79.7 0.0 2.5e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DoxX_2 PF13564.6 ABK75517.1 - 1.5e-06 28.2 12.2 1.5e-06 28.2 12.2 2.3 1 1 1 2 2 2 2 DoxX-like family DoxX PF07681.12 ABK75517.1 - 3.2 8.4 18.7 0.053 14.1 9.1 2.4 2 1 1 3 3 3 0 DoxX Acetyltransf_6 PF13480.7 ABK75518.1 - 2.2e-40 138.1 7.1 5.9e-40 136.7 2.7 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Peptidase_A8 PF01252.18 ABK75519.1 - 2.9e-30 105.4 2.3 3.4e-30 105.1 2.3 1.0 1 0 0 1 1 1 1 Signal peptidase (SPase) II CPP1-like PF11833.8 ABK75519.1 - 0.33 10.6 1.1 0.44 10.2 0.5 1.4 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF3094 PF11293.8 ABK75519.1 - 6.5 6.6 6.9 5.7 6.7 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) SnoaL_2 PF12680.7 ABK75520.1 - 0.0012 19.4 0.2 0.0016 19.1 0.2 1.2 1 0 0 1 1 1 1 SnoaL-like domain DDE_Tnp_1 PF01609.21 ABK75521.1 - 1.9e-13 50.5 0.0 6.9e-13 48.7 0.0 1.8 1 1 0 1 1 1 1 Transposase DDE domain FUSC_2 PF13515.6 ABK75522.1 - 3.2e-10 40.2 15.3 3.2e-10 40.2 15.3 3.3 2 1 1 3 3 3 1 Fusaric acid resistance protein-like FUSC-like PF12805.7 ABK75522.1 - 0.0024 17.0 6.8 0.0035 16.5 5.5 1.9 2 0 0 2 2 2 1 FUSC-like inner membrane protein yccS FUSC PF04632.12 ABK75522.1 - 0.012 14.2 67.8 0.0037 15.9 34.9 2.5 2 1 0 2 2 2 0 Fusaric acid resistance protein family GntP_permease PF02447.16 ABK75523.1 - 2.1e-116 389.2 37.5 2.5e-116 389.0 37.5 1.0 1 0 0 1 1 1 1 GntP family permease CitMHS PF03600.16 ABK75523.1 - 7.5e-25 87.7 42.0 7.5e-25 87.7 42.0 1.7 1 1 0 1 1 1 1 Citrate transporter Na_H_antiport_2 PF13726.6 ABK75523.1 - 0.018 15.2 13.0 0.018 15.2 13.0 4.3 5 1 0 5 5 5 0 Na+-H+ antiporter family SLATT_2 PF18183.1 ABK75524.1 - 0.011 15.5 0.2 0.013 15.3 0.2 1.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 2 Bac_luciferase PF00296.20 ABK75525.1 - 3.2e-45 154.9 8.8 4.5e-45 154.4 8.8 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase ChaB PF06150.12 ABK75526.1 - 4.5e-18 65.6 3.2 8.4e-18 64.7 3.2 1.5 1 0 0 1 1 1 1 ChaB Rho_N PF07498.12 ABK75526.1 - 1.7e-07 31.0 0.7 7.1e-07 29.0 0.1 2.1 2 0 0 2 2 2 1 Rho termination factor, N-terminal domain TPR_12 PF13424.6 ABK75526.1 - 0.02 15.2 1.6 0.02 15.2 1.6 1.6 2 0 0 2 2 2 0 Tetratricopeptide repeat HTH_20 PF12840.7 ABK75527.1 - 1e-12 47.9 1.7 1.6e-12 47.3 1.1 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_5 PF01022.20 ABK75527.1 - 5.5e-07 29.4 0.1 1e-06 28.5 0.0 1.5 2 0 0 2 2 1 1 Bacterial regulatory protein, arsR family HTH_28 PF13518.6 ABK75527.1 - 7e-06 26.1 2.3 8.1e-06 25.9 0.7 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 ABK75527.1 - 8.2e-05 22.4 2.8 9.1e-05 22.3 1.1 1.8 2 0 0 2 2 2 1 MarR family MarR PF01047.22 ABK75527.1 - 0.00016 21.5 0.1 0.0016 18.3 0.0 2.2 1 1 1 2 2 2 1 MarR family HTH_11 PF08279.12 ABK75527.1 - 0.00031 20.6 0.6 0.00055 19.8 0.1 1.7 2 0 0 2 2 2 1 HTH domain HTH_24 PF13412.6 ABK75527.1 - 0.0035 16.9 0.0 0.011 15.3 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding GntR PF00392.21 ABK75527.1 - 0.0043 16.7 2.1 0.0072 16.0 0.5 2.1 1 1 1 2 2 2 1 Bacterial regulatory proteins, gntR family Fe_dep_repress PF01325.19 ABK75527.1 - 0.0044 17.2 0.6 0.35 11.1 0.1 2.2 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain HTH_41 PF14502.6 ABK75527.1 - 0.0051 16.5 0.5 0.017 14.8 0.1 2.0 3 0 0 3 3 3 1 Helix-turn-helix domain DUF4423 PF14394.6 ABK75527.1 - 0.013 15.2 0.1 0.017 14.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) Rrf2 PF02082.20 ABK75527.1 - 0.014 15.7 0.2 0.033 14.5 0.1 1.7 1 1 1 2 2 2 0 Transcriptional regulator Poty_PP PF08440.10 ABK75527.1 - 0.025 13.6 0.2 0.029 13.5 0.2 1.0 1 0 0 1 1 1 0 Potyviridae polyprotein TrmB PF01978.19 ABK75527.1 - 0.05 13.5 0.1 0.11 12.3 0.1 1.5 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_27 PF13463.6 ABK75527.1 - 0.069 13.7 0.1 0.14 12.7 0.1 1.7 1 1 0 1 1 1 0 Winged helix DNA-binding domain Bot1p PF12298.8 ABK75527.1 - 0.069 13.3 0.1 0.15 12.2 0.1 1.5 1 1 0 2 2 2 0 Eukaryotic mitochondrial regulator protein HTH_45 PF14947.6 ABK75527.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix HTH_36 PF13730.6 ABK75527.1 - 0.18 11.8 0.0 0.83 9.7 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain PGM_PMM_I PF02878.16 ABK75528.1 - 1.5e-36 125.2 0.0 2.8e-36 124.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 ABK75528.1 - 3.1e-27 95.0 0.0 7.2e-27 93.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 ABK75528.1 - 8.4e-12 45.6 0.1 3.6e-11 43.6 0.1 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 ABK75528.1 - 3.2e-09 36.8 0.0 1.5e-08 34.6 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Amidohydro_3 PF07969.11 ABK75529.1 - 5.6e-75 253.6 9.1 6.8e-75 253.3 9.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 ABK75529.1 - 7.7e-10 38.6 0.0 5.3e-09 35.8 0.0 2.2 3 0 0 3 3 3 1 Amidohydrolase family rve PF00665.26 ABK75530.1 - 7.8e-19 68.0 0.1 2.2e-18 66.6 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 ABK75530.1 - 9.6e-15 54.1 0.5 1.8e-14 53.2 0.5 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 ABK75530.1 - 5.9e-06 26.6 0.0 8.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 DDE domain HTH_32 PF13565.6 ABK75530.1 - 0.001 19.6 4.1 0.0013 19.2 0.0 2.7 3 0 0 3 3 3 1 Homeodomain-like domain rve_2 PF13333.6 ABK75530.1 - 0.0033 17.5 0.0 0.0083 16.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain BPD_transp_1 PF00528.22 ABK75532.1 - 4.4e-32 111.3 9.3 4.4e-32 111.3 9.3 1.7 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF599 PF04654.12 ABK75533.1 - 0.034 13.6 0.9 0.053 12.9 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF599 SPC25 PF06703.11 ABK75533.1 - 0.19 11.5 0.9 0.18 11.6 0.4 1.4 1 1 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF2244 PF10003.9 ABK75533.1 - 1.7 8.3 10.5 0.9 9.2 4.5 2.0 1 1 1 2 2 2 0 Integral membrane protein (DUF2244) ACOX PF01756.19 ABK75534.1 - 4.9e-22 78.4 0.1 8.5e-22 77.6 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 ABK75534.1 - 1e-17 64.1 0.0 1.9e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 ABK75534.1 - 8.6e-14 52.0 1.2 2.1e-13 50.7 1.2 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK75534.1 - 4e-06 27.5 1.3 2.1e-05 25.2 0.2 2.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain DUF932 PF06067.11 ABK75534.1 - 0.042 13.6 0.2 0.15 11.8 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF932) Acyl-CoA_dh_2 PF08028.11 ABK75534.1 - 2.4 8.4 10.6 0.17 12.2 3.2 2.8 2 2 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Sigma70_r2 PF04542.14 ABK75535.1 - 1.8e-13 50.1 4.1 6.4e-13 48.3 0.7 2.5 3 0 0 3 3 3 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 ABK75535.1 - 1.8e-11 43.5 0.0 2.9e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 SnoaL_2 PF12680.7 ABK75535.1 - 2.4e-07 31.4 0.2 1.9e-06 28.4 0.0 2.5 2 1 0 2 2 2 1 SnoaL-like domain Sigma70_r4 PF04545.16 ABK75535.1 - 3.1e-06 26.6 0.0 6.4e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 DUF4440 PF14534.6 ABK75535.1 - 0.0066 16.8 0.0 0.015 15.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) MarR_2 PF12802.7 ABK75535.1 - 0.079 12.9 0.0 0.24 11.3 0.0 1.8 1 0 0 1 1 1 0 MarR family FAD_binding_5 PF00941.21 ABK75536.1 - 2.6e-49 167.2 0.0 4e-49 166.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 ABK75536.1 - 0.0011 19.2 0.0 0.0024 18.0 0.0 1.6 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain DUF4440 PF14534.6 ABK75537.1 - 8.5e-17 61.5 0.2 1.1e-16 61.2 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 ABK75537.1 - 1.6e-11 44.7 0.9 2.1e-11 44.3 0.9 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 ABK75537.1 - 1.8e-10 41.0 1.3 2.2e-10 40.8 1.3 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 ABK75537.1 - 1.7e-09 37.9 0.0 2.4e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain GGDEF_2 PF17853.1 ABK75537.1 - 0.00018 21.8 0.4 0.00046 20.4 0.1 1.7 2 0 0 2 2 2 1 GGDEF-like domain SnoaL PF07366.12 ABK75537.1 - 0.0024 17.7 0.2 0.0032 17.3 0.2 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase Lumazine_bd_2 PF12893.7 ABK75537.1 - 0.019 15.6 0.0 0.043 14.5 0.0 1.6 2 0 0 2 2 2 0 Putative lumazine-binding LPAM_2 PF13627.6 ABK75537.1 - 0.21 11.5 2.6 0.35 10.8 2.6 1.4 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site TetR_N PF00440.23 ABK75538.1 - 7.4e-13 48.1 1.1 7.4e-13 48.1 1.1 2.4 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_14 PF17754.1 ABK75538.1 - 0.0003 20.7 9.2 0.0003 20.7 9.2 1.7 1 1 1 2 2 2 1 MftR C-terminal domain HTH_Tnp_1_2 PF13022.6 ABK75538.1 - 0.0094 16.1 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of insertion element transposase HTH_23 PF13384.6 ABK75538.1 - 0.35 10.7 0.0 0.35 10.7 0.0 2.2 3 0 0 3 3 3 0 Homeodomain-like domain HTH_18 PF12833.7 ABK75538.1 - 0.78 10.0 4.4 0.62 10.4 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Proton_antipo_M PF00361.20 ABK75540.1 - 8.3e-65 218.9 23.9 8.3e-65 218.9 23.9 2.2 3 0 0 3 3 3 1 Proton-conducting membrane transporter Oxidored_q5_N PF01059.17 ABK75540.1 - 0.0077 16.3 0.2 0.0077 16.3 0.2 3.2 2 1 1 3 3 3 1 NADH-ubiquinone oxidoreductase chain 4, amino terminus NAD_binding_2 PF03446.15 ABK75541.1 - 4.4e-20 72.4 0.1 7.8e-20 71.6 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ABK75541.1 - 5e-08 33.4 0.1 1e-07 32.4 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 ABK75541.1 - 1.7e-05 24.9 0.0 2.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 ABK75541.1 - 3.8e-05 23.4 0.1 6.5e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 ABK75541.1 - 4e-05 23.6 0.1 9e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.18 ABK75541.1 - 0.00026 21.2 0.0 0.00052 20.3 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.18 ABK75541.1 - 0.00059 19.8 0.1 0.00095 19.1 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 ABK75541.1 - 0.00066 19.1 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 ABK75541.1 - 0.0022 17.5 0.0 0.0034 16.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family IlvN PF07991.12 ABK75541.1 - 0.0063 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain XdhC_C PF13478.6 ABK75541.1 - 0.05 14.1 0.4 0.094 13.2 0.1 1.6 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_10 PF13460.6 ABK75541.1 - 0.069 13.0 2.8 0.06 13.2 0.6 1.9 2 0 0 2 2 2 0 NAD(P)H-binding Glu-tRNAGln PF02686.15 ABK75542.1 - 1.4e-19 70.2 0.0 1.8e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit FAD_binding_3 PF01494.19 ABK75543.1 - 3.7e-59 200.7 0.0 4.5e-59 200.5 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ABK75543.1 - 5.1e-07 29.8 0.2 1.5e-06 28.3 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 ABK75543.1 - 1.4e-05 24.1 0.2 0.62 8.8 0.0 3.0 2 1 1 3 3 3 2 Tryptophan halogenase DAO PF01266.24 ABK75543.1 - 1.5e-05 24.8 1.7 0.015 14.9 0.2 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ABK75543.1 - 2.7e-05 23.6 0.0 0.0005 19.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ABK75543.1 - 3.3e-05 23.2 0.8 0.0095 15.1 0.5 2.4 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 ABK75543.1 - 9.6e-05 22.9 0.0 0.002 18.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ABK75543.1 - 0.00024 19.9 0.0 0.00098 17.9 0.1 1.9 3 0 0 3 3 3 1 HI0933-like protein SE PF08491.10 ABK75543.1 - 0.00096 18.3 0.0 0.6 9.1 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase Pyr_redox_3 PF13738.6 ABK75543.1 - 0.0052 16.1 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ABK75543.1 - 0.035 13.2 0.1 0.053 12.6 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 ABK75543.1 - 0.063 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 ABK75543.1 - 0.12 12.3 0.1 1.1 9.3 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 ABK75543.1 - 0.13 11.6 0.5 6.3 6.0 0.7 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ABK75543.1 - 0.14 11.2 1.2 0.53 9.3 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Zincin_1 PF06262.11 ABK75544.1 - 1.6e-34 117.8 0.4 2.2e-34 117.4 0.4 1.1 1 0 0 1 1 1 1 Zincin-like metallopeptidase GIT_SHD PF08518.11 ABK75544.1 - 0.097 12.3 0.1 0.097 12.3 0.1 2.1 2 0 0 2 2 2 0 Spa2 homology domain (SHD) of GIT 2Fe-2S_thioredx PF01257.19 ABK75546.1 - 4.8e-40 136.8 0.0 6e-40 136.4 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Gas_vesicle PF00741.18 ABK75547.1 - 2e-16 59.9 9.9 2.4e-16 59.6 9.9 1.1 1 0 0 1 1 1 1 Gas vesicle protein BPD_transp_1 PF00528.22 ABK75548.1 - 7.4e-24 84.5 17.8 7.4e-24 84.5 17.8 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component SRP54 PF00448.22 ABK75549.1 - 2.1e-72 242.9 0.3 2.7e-72 242.5 0.3 1.1 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 ABK75549.1 - 3.2e-07 30.5 0.0 6.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.6 ABK75549.1 - 1.5e-06 28.1 4.1 1.5e-06 28.1 4.1 1.8 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 ABK75549.1 - 1.5e-05 25.4 0.1 2.7e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain CbiA PF01656.23 ABK75549.1 - 2.5e-05 24.4 0.0 6.4e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 ABK75549.1 - 0.0028 16.9 0.0 0.0044 16.3 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.6 ABK75549.1 - 0.0045 17.3 0.2 0.0079 16.5 0.2 1.4 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 ABK75549.1 - 0.0059 15.6 0.2 0.0059 15.6 0.2 2.1 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 ABK75549.1 - 0.011 15.7 3.0 0.1 12.5 0.3 2.2 1 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 ABK75549.1 - 0.012 15.9 0.0 0.021 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ABK75549.1 - 0.012 15.3 0.0 0.021 14.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ABK75549.1 - 0.02 15.1 0.1 0.034 14.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain Phage_holin_3_6 PF07332.11 ABK75549.1 - 0.027 14.5 0.6 0.067 13.2 0.6 1.7 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III MMR_HSR1 PF01926.23 ABK75549.1 - 0.037 14.1 2.5 0.067 13.3 1.1 2.2 2 1 0 2 2 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 ABK75549.1 - 0.053 13.8 0.4 0.11 12.8 0.1 1.6 2 0 0 2 2 1 0 AAA domain AAA_5 PF07728.14 ABK75549.1 - 0.073 13.1 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SARG PF15385.6 ABK75549.1 - 0.092 12.0 3.5 0.13 11.5 3.5 1.1 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein Rad17 PF03215.15 ABK75549.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 ABK75549.1 - 0.14 11.9 0.1 0.28 11.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain APS_kinase PF01583.20 ABK75549.1 - 0.14 12.0 0.1 0.29 11.0 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA PF00004.29 ABK75549.1 - 0.16 12.4 0.2 0.3 11.5 0.2 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 ABK75549.1 - 0.18 11.5 0.3 4.4 7.0 0.0 2.1 1 1 1 2 2 2 0 IstB-like ATP binding protein VirC1 PF07015.11 ABK75549.1 - 0.19 11.0 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 VirC1 protein Thymidylate_kin PF02223.17 ABK75549.1 - 0.2 11.3 0.1 0.32 10.6 0.1 1.3 1 0 0 1 1 1 0 Thymidylate kinase Cytomega_UL20A PF05984.12 ABK75549.1 - 0.2 12.0 0.2 0.7 10.2 0.0 1.9 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein NTPase_1 PF03266.15 ABK75549.1 - 0.23 11.3 2.9 1.9 8.4 2.5 2.3 1 1 0 1 1 1 0 NTPase DUF2075 PF09848.9 ABK75549.1 - 0.27 10.5 0.0 0.37 10.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.19 ABK75549.1 - 0.89 9.1 5.6 8.1 6.0 5.6 2.0 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SprB PF13573.6 ABK75550.1 - 0.87 9.4 4.8 0.83 9.5 1.7 2.4 2 0 0 2 2 2 0 SprB repeat DUF1003 PF06210.11 ABK75551.1 - 2.8e-39 133.4 0.6 3.5e-39 133.1 0.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1003) CENP-F_leu_zip PF10473.9 ABK75551.1 - 0.0025 17.8 1.0 0.0036 17.3 1.0 1.1 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3340 PF11818.8 ABK75551.1 - 0.012 15.8 0.3 0.016 15.4 0.3 1.1 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) rve PF00665.26 ABK75552.1 - 6.9e-19 68.2 0.1 1.9e-18 66.8 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 ABK75552.1 - 9.6e-15 54.1 0.5 1.8e-14 53.2 0.5 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 ABK75552.1 - 1.1e-06 29.0 0.0 1.6e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 DDE domain HTH_32 PF13565.6 ABK75552.1 - 0.003 18.1 4.0 0.0042 17.7 0.0 2.7 3 0 0 3 3 3 1 Homeodomain-like domain rve_2 PF13333.6 ABK75552.1 - 0.0034 17.5 0.0 0.0083 16.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DUF4459 PF14673.6 ABK75552.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4459) FMN_dh PF01070.18 ABK75553.1 - 7.1e-07 28.6 0.3 1e-06 28.0 0.3 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Polyketide_cyc2 PF10604.9 ABK75554.1 - 3.3e-07 30.7 4.5 3.6e-06 27.3 4.5 2.0 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 ABK75554.1 - 0.025 14.8 0.1 0.051 13.8 0.1 1.6 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport HMGL-like PF00682.19 ABK75555.1 - 7.6e-38 130.6 0.0 9.3e-38 130.3 0.0 1.0 1 0 0 1 1 1 1 HMGL-like PHP_C PF13263.6 ABK75555.1 - 0.046 13.5 0.2 0.17 11.7 0.2 2.0 1 0 0 1 1 1 0 PHP-associated TetR_N PF00440.23 ABK75556.1 - 1.9e-06 27.5 0.0 3.6e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family DUF4380 PF14315.6 ABK75557.1 - 1.9e-11 43.4 0.4 2.2e-10 40.0 0.4 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4380) PorA PF11271.8 ABK75558.1 - 3.5e-97 325.3 3.3 4.2e-97 325.1 3.3 1.0 1 0 0 1 1 1 1 Porin PorA CD36 PF01130.21 ABK75558.1 - 0.1 11.1 0.0 0.19 10.2 0.0 1.4 1 0 0 1 1 1 0 CD36 family WXG100 PF06013.12 ABK75559.1 - 2.8e-13 49.9 4.4 3.5e-13 49.6 4.4 1.0 1 0 0 1 1 1 1 Proteins of 100 residues with WXG Apolipoprotein PF01442.18 ABK75559.1 - 0.046 13.6 0.0 0.059 13.2 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain BPD_transp_1 PF00528.22 ABK75561.1 - 6.4e-23 81.5 11.8 6.4e-23 81.5 11.8 1.7 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component CN_hydrolase PF00795.22 ABK75562.1 - 6.7e-15 55.1 0.0 1e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Methyltransf_11 PF08241.12 ABK75563.1 - 2e-21 76.5 0.0 3.4e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABK75563.1 - 2.2e-19 70.0 0.1 4.4e-19 69.0 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABK75563.1 - 3.6e-18 65.9 0.0 4.8e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABK75563.1 - 1.5e-17 63.8 0.0 3.2e-17 62.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ABK75563.1 - 3.1e-13 49.6 0.0 4.5e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ABK75563.1 - 3.2e-10 40.6 0.0 5.8e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ABK75563.1 - 4.5e-06 26.1 0.0 7.3e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.15 ABK75563.1 - 0.0016 18.4 0.0 0.47 10.3 0.0 2.2 2 0 0 2 2 2 2 Hypothetical methyltransferase MetW PF07021.12 ABK75563.1 - 0.0021 17.7 0.1 0.02 14.5 0.1 2.1 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 ABK75563.1 - 0.0034 17.0 0.0 0.0079 15.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 ABK75563.1 - 0.017 14.1 0.0 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Cons_hypoth95 PF03602.15 ABK75563.1 - 0.041 13.5 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 NodS PF05401.11 ABK75563.1 - 0.07 12.7 0.0 0.19 11.3 0.0 1.7 1 1 0 1 1 1 0 Nodulation protein S (NodS) PCMT PF01135.19 ABK75563.1 - 0.076 12.8 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.14 ABK75563.1 - 0.081 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB DUF561 PF04481.12 ABK75563.1 - 0.083 12.0 0.0 5.4 6.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF561) DUF3107 PF11305.8 ABK75564.1 - 2e-30 104.9 0.1 2.2e-30 104.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3107) TLP1_add_C PF18313.1 ABK75565.1 - 1.6e-30 104.9 2.6 3.3e-30 103.9 2.6 1.6 1 0 0 1 1 1 1 Thiolase-like protein type 1 additional C-terminal domain Thiolase_C PF02803.18 ABK75565.1 - 0.057 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Thiolase, C-terminal domain OB_aCoA_assoc PF01796.17 ABK75565.1 - 0.075 13.0 1.6 0.13 12.3 0.5 2.1 2 0 0 2 2 2 0 DUF35 OB-fold domain, acyl-CoA-associated Holin_2-3 PF13272.6 ABK75565.1 - 0.18 12.1 0.1 0.48 10.8 0.0 1.7 2 0 0 2 2 2 0 Putative 2/3 transmembrane domain holin SEC-C PF02810.15 ABK75566.1 - 5.2e-10 39.0 7.6 7.8e-10 38.5 7.6 1.3 1 0 0 1 1 1 1 SEC-C motif TPR_4 PF07721.14 ABK75566.1 - 0.0011 19.4 20.6 0.046 14.4 1.8 5.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 ABK75566.1 - 0.0055 17.2 1.6 1.1 9.9 0.3 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 ABK75566.1 - 0.0084 16.7 22.7 0.57 10.9 7.6 5.5 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 ABK75566.1 - 0.032 15.0 22.6 1.9 9.6 0.6 7.6 6 1 2 8 8 8 0 Tetratricopeptide repeat DUF2384 PF09722.10 ABK75566.1 - 0.061 13.4 4.5 0.36 10.9 0.1 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2384) TPR_7 PF13176.6 ABK75566.1 - 0.074 13.1 0.0 3.4 7.9 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 ABK75566.1 - 0.35 10.8 2.4 1.5 8.8 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.16 ABK75567.1 - 3.4e-24 85.4 64.7 8.6e-23 80.8 46.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ABK75567.1 - 0.01 15.2 44.4 0.14 11.4 18.1 2.2 1 1 1 2 2 2 0 Uncharacterised MFS-type transporter YbfB FMO-like PF00743.19 ABK75568.1 - 1e-74 251.9 0.0 1.5e-74 251.3 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ABK75568.1 - 3.3e-15 56.1 0.0 1.7e-12 47.2 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ABK75568.1 - 2.2e-09 36.9 0.0 2.1e-08 33.7 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ABK75568.1 - 1.1e-07 32.0 0.1 4.7e-07 29.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ABK75568.1 - 2e-07 30.6 0.0 2.1e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ABK75568.1 - 0.00054 20.5 0.0 0.22 12.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ABK75568.1 - 0.034 14.2 1.7 0.9 9.5 0.6 3.3 3 1 0 3 3 3 0 FAD-NAD(P)-binding DUF2236 PF09995.9 ABK75570.1 - 1.1e-08 35.6 0.3 1.8e-08 34.9 0.3 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) GMC_oxred_C PF05199.13 ABK75571.1 - 7.7e-19 68.6 0.1 2e-18 67.3 0.1 1.8 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 ABK75571.1 - 1.1e-13 51.2 0.8 1.5e-11 44.2 0.8 2.9 1 1 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 ABK75571.1 - 4.5e-05 23.6 1.8 0.00042 20.5 0.7 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ABK75571.1 - 4.8e-05 22.7 0.0 8e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ABK75571.1 - 0.00039 19.2 0.1 0.00061 18.6 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 ABK75571.1 - 0.00072 18.7 11.0 0.015 14.4 11.0 2.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 ABK75571.1 - 0.0008 19.1 4.8 0.008 15.8 4.8 2.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ABK75571.1 - 0.0013 18.1 0.1 0.0024 17.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 ABK75571.1 - 0.0043 16.4 0.0 0.0061 15.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ABK75571.1 - 0.0068 15.5 0.1 0.011 14.8 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 ABK75571.1 - 0.035 13.2 0.8 0.049 12.7 0.8 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 ABK75571.1 - 0.037 13.3 0.1 0.066 12.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 ABK75571.1 - 0.093 12.1 1.7 0.16 11.3 1.7 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase SufE PF02657.15 ABK75572.1 - 2.4e-30 104.9 0.0 2.7e-30 104.7 0.0 1.0 1 0 0 1 1 1 1 Fe-S metabolism associated domain SsgA PF04686.12 ABK75572.1 - 0.083 12.9 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Streptomyces sporulation and cell division protein, SsgA Peptidase_M20 PF01546.28 ABK75573.1 - 5e-27 94.9 1.6 6.6e-27 94.5 1.6 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 ABK75573.1 - 0.0057 16.4 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 YjbR PF04237.13 ABK75574.1 - 3.4e-08 33.9 0.0 4.2e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 YjbR Bac_luciferase PF00296.20 ABK75575.1 - 8.3e-59 199.6 7.2 2.4e-58 198.0 7.2 1.6 1 1 0 1 1 1 1 Luciferase-like monooxygenase sCache_3_2 PF17203.4 ABK75575.1 - 0.027 14.6 0.0 0.061 13.4 0.0 1.5 1 0 0 1 1 1 0 Single cache domain 3 COesterase PF00135.28 ABK75576.1 - 7.8e-79 265.9 0.0 1.3e-78 265.2 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ABK75576.1 - 3e-12 46.8 0.4 6.4e-12 45.8 0.4 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold SNCAIP_SNCA_bd PF16700.5 ABK75577.1 - 0.056 13.2 1.0 0.063 13.0 1.0 1.1 1 0 0 1 1 1 0 Synphilin-1 alpha-Synuclein-binding domain SIS PF01380.22 ABK75578.1 - 1.5e-22 79.8 0.3 2.9e-22 78.9 0.1 1.5 2 0 0 2 2 2 1 SIS domain HTH_6 PF01418.17 ABK75578.1 - 2.7e-16 59.3 0.0 5.9e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family SIS_2 PF13580.6 ABK75578.1 - 5.3e-06 26.5 0.4 4.9e-05 23.4 0.4 2.4 1 1 1 2 2 2 1 SIS domain TauE PF01925.19 ABK75579.1 - 0.013 15.2 0.1 0.017 14.7 0.1 1.1 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE SOG2 PF10428.9 ABK75579.1 - 0.044 13.0 2.2 0.06 12.5 2.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF2269 PF10027.9 ABK75579.1 - 0.06 13.4 1.1 0.16 12.0 1.1 1.7 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) Thiolase_N PF00108.23 ABK75580.1 - 1.2e-54 185.4 0.2 3.4e-54 183.9 0.1 1.8 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ABK75580.1 - 2.2e-39 133.9 0.7 7.8e-39 132.1 0.6 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 ABK75580.1 - 0.00059 19.9 0.3 0.0017 18.5 0.3 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Pept_tRNA_hydro PF01195.19 ABK75581.1 - 2.3e-58 196.9 0.0 2.7e-58 196.7 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Haem_oxygenas_2 PF14518.6 ABK75582.1 - 1.6e-42 145.3 1.3 2.4e-42 144.7 1.3 1.3 1 0 0 1 1 1 1 Iron-containing redox enzyme DUF3298 PF11738.8 ABK75583.1 - 4.4e-16 59.7 0.0 7.5e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3298) MVL PF12151.8 ABK75583.1 - 0.0028 17.5 0.0 0.005 16.7 0.0 1.5 1 0 0 1 1 1 1 Mannan-binding protein DUF202 PF02656.15 ABK75584.1 - 3.3e-13 49.9 3.6 3.3e-13 49.9 3.6 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF202) CopD PF05425.13 ABK75584.1 - 0.023 15.1 9.0 0.029 14.8 9.0 1.2 1 0 0 1 1 1 0 Copper resistance protein D ResB PF05140.14 ABK75584.1 - 0.024 13.4 0.4 0.027 13.2 0.4 1.1 1 0 0 1 1 1 0 ResB-like family DUF4536 PF15055.6 ABK75584.1 - 0.095 12.9 0.9 0.22 11.8 0.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4536) KdpD PF02702.17 ABK75585.1 - 7.2e-98 326.2 0.4 1.7e-97 325.0 0.1 1.8 2 0 0 2 2 2 1 Osmosensitive K+ channel His kinase sensor domain DUF4118 PF13493.6 ABK75585.1 - 1.2e-26 92.5 9.7 2.4e-26 91.6 9.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4118) HATPase_c PF02518.26 ABK75585.1 - 3e-19 69.6 0.0 1.3e-18 67.5 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ABK75585.1 - 2.5e-12 46.6 0.4 1.3e-11 44.3 0.4 2.4 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Usp PF00582.26 ABK75585.1 - 3.5e-11 43.8 0.9 3.5e-11 43.8 0.9 3.6 2 2 1 3 3 3 1 Universal stress protein family ATP_bind_3 PF01171.20 ABK75585.1 - 0.035 13.8 0.1 0.07 12.9 0.1 1.5 1 0 0 1 1 1 0 PP-loop family FCD PF07729.12 ABK75586.1 - 2.5e-22 79.6 9.0 2.5e-22 79.6 9.0 1.5 2 0 0 2 2 2 1 FCD domain GntR PF00392.21 ABK75586.1 - 5.6e-22 77.2 0.1 1.3e-21 76.0 0.1 1.6 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family PaaX PF07848.12 ABK75586.1 - 0.00015 21.9 0.3 0.00041 20.5 0.0 1.8 2 0 0 2 2 2 1 PaaX-like protein Rrf2 PF02082.20 ABK75586.1 - 0.00017 21.8 0.0 0.00036 20.8 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator HTH_11 PF08279.12 ABK75586.1 - 0.00067 19.6 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 HTH domain MarR_2 PF12802.7 ABK75586.1 - 0.00078 19.3 0.3 0.0065 16.3 0.0 2.5 2 0 0 2 2 2 1 MarR family HTH_41 PF14502.6 ABK75586.1 - 0.0087 15.7 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 ABK75586.1 - 0.0087 15.6 0.1 0.017 14.7 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding FadR_C PF07840.12 ABK75586.1 - 0.022 14.7 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 FadR C-terminal domain HTH_Crp_2 PF13545.6 ABK75586.1 - 0.026 14.5 0.0 0.062 13.3 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain TrmB PF01978.19 ABK75586.1 - 0.065 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB FMN_bind_2 PF04299.12 ABK75587.1 - 5.7e-52 175.8 0.0 7.2e-52 175.5 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain Pyridox_ox_2 PF12900.7 ABK75587.1 - 7.9e-05 22.7 0.3 0.00012 22.1 0.3 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase SmpB PF01668.18 ABK75588.1 - 5.4e-61 204.7 0.2 6.3e-61 204.5 0.2 1.0 1 0 0 1 1 1 1 SmpB protein DUF5439 PF17507.2 ABK75588.1 - 0.092 13.0 0.3 14 6.0 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5439) Glyoxalase PF00903.25 ABK75589.1 - 1.8e-07 31.4 0.1 4e-07 30.3 0.1 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 ABK75589.1 - 0.00016 21.6 0.0 0.00028 20.8 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 ABK75589.1 - 0.0016 19.2 0.1 0.0044 17.8 0.1 1.6 1 1 0 1 1 1 1 Glyoxalase-like domain MlaD PF02470.20 ABK75590.1 - 1.7e-11 44.3 0.4 3.2e-11 43.4 0.4 1.4 1 0 0 1 1 1 1 MlaD protein Mce4_CUP1 PF11887.8 ABK75590.1 - 4.7e-07 29.5 2.6 0.00088 18.8 0.6 2.2 1 1 1 2 2 2 2 Cholesterol uptake porter CUP1 of Mce4, putative DUF948 PF06103.11 ABK75590.1 - 0.00089 19.5 5.2 0.18 12.1 0.6 2.7 2 1 1 3 3 3 2 Bacterial protein of unknown function (DUF948) PLAC9 PF15205.6 ABK75590.1 - 0.0036 17.7 0.1 0.019 15.4 0.0 2.3 2 0 0 2 2 2 1 Placenta-specific protein 9 DUF1664 PF07889.12 ABK75590.1 - 0.078 13.0 1.6 0.7 9.9 0.2 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Sec34 PF04136.15 ABK75590.1 - 0.2 11.5 0.2 0.64 9.9 0.1 1.7 1 1 1 2 2 2 0 Sec34-like family NPV_P10 PF05531.12 ABK75590.1 - 2.5 8.6 4.8 1.8 9.1 0.5 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein GTP_cyclohydroI PF01227.22 ABK75591.1 - 1.6e-77 259.0 0.0 1.9e-77 258.8 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I AAA_22 PF13401.6 ABK75591.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Flavodoxin_2 PF02525.17 ABK75592.1 - 3.4e-53 180.3 0.0 4.3e-53 180.0 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 ABK75592.1 - 9.9e-12 44.9 0.0 1.9e-11 44.0 0.0 1.5 2 0 0 2 2 2 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.7 ABK75592.1 - 0.031 14.0 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 Flavodoxin AMP-binding PF00501.28 ABK75593.1 - 5.8e-50 170.1 0.2 1.3e-49 169.0 0.2 1.5 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK75593.1 - 1.2e-16 61.4 8.3 2.2e-16 60.6 1.8 3.0 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain TetR_N PF00440.23 ABK75594.1 - 3.6e-10 39.5 0.6 9e-10 38.2 0.6 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 ABK75594.1 - 0.0021 18.3 2.2 0.0021 18.3 2.2 2.1 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain adh_short_C2 PF13561.6 ABK75595.1 - 6e-63 212.5 1.9 7.3e-63 212.3 1.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK75595.1 - 3e-56 190.0 0.9 3.5e-56 189.8 0.9 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK75595.1 - 5.4e-09 36.2 3.0 1.1e-08 35.3 2.9 1.4 1 1 0 1 1 1 1 KR domain MaoC_dehydratas PF01575.19 ABK75596.1 - 1.2e-28 99.1 0.0 2.2e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 ABK75596.1 - 1.2e-17 64.3 0.0 5e-15 55.8 0.0 2.2 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase CoA_transf_3 PF02515.17 ABK75597.1 - 6.7e-80 269.0 0.1 7.5e-80 268.8 0.1 1.0 1 0 0 1 1 1 1 CoA-transferase family III Lactonase PF10282.9 ABK75599.1 - 1.2e-08 34.6 0.4 0.00039 19.8 0.0 2.9 2 1 1 3 3 3 2 Lactonase, 7-bladed beta-propeller SGL PF08450.12 ABK75599.1 - 0.00023 20.8 0.2 0.023 14.3 0.0 3.1 1 1 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region TMEM132 PF16070.5 ABK75599.1 - 0.054 12.8 0.1 0.65 9.3 0.0 2.2 2 0 0 2 2 2 0 Transmembrane protein family 132 PQQ_3 PF13570.6 ABK75599.1 - 1.4 9.5 16.0 0.56 10.8 0.4 5.5 5 1 1 6 6 6 0 PQQ-like domain Nitroreductase PF00881.24 ABK75601.1 - 3.2e-28 98.9 0.0 4.6e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 ABK75601.1 - 3.4e-07 30.1 0.1 0.093 12.3 0.0 3.0 2 1 1 3 3 3 3 Putative TM nitroreductase Pro-kuma_activ PF09286.11 ABK75602.1 - 2e-05 24.9 0.0 3.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 ABK75602.1 - 0.034 13.4 0.2 0.046 13.0 0.2 1.2 1 0 0 1 1 1 0 Subtilase family Lysine_decarbox PF03641.14 ABK75603.1 - 3.3e-24 85.5 0.1 4e-24 85.2 0.1 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 ABK75603.1 - 9.8e-14 51.2 0.1 1.2e-13 50.9 0.1 1.2 1 0 0 1 1 1 1 SLOG cluster4 family LSDAT_prok PF18171.1 ABK75603.1 - 0.02 14.2 0.2 0.43 9.8 0.1 2.1 2 0 0 2 2 2 0 SLOG in TRPM, prokaryote Amdase PF17645.1 ABK75603.1 - 0.077 12.6 0.0 0.097 12.3 0.0 1.2 1 0 0 1 1 1 0 Arylmalonate decarboxylase Ribosomal_L36 PF00444.18 ABK75604.1 - 1.8e-18 66.4 7.8 2e-18 66.3 7.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L36 DUF899 PF05988.12 ABK75605.1 - 2.9e-53 180.6 0.0 6.5e-53 179.4 0.0 1.4 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF899) DUF4190 PF13828.6 ABK75606.1 - 6.6e-10 38.6 20.8 1e-09 38.0 20.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4190) Yip1 PF04893.17 ABK75606.1 - 4.1 7.1 15.2 20 4.9 15.1 1.8 1 1 0 1 1 1 0 Yip1 domain Prominin PF05478.11 ABK75606.1 - 8.4 4.2 6.3 11 3.8 6.3 1.0 1 0 0 1 1 1 0 Prominin Bac_luciferase PF00296.20 ABK75607.1 - 1e-36 126.9 3.6 1.3e-36 126.6 3.6 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Pyr_redox_2 PF07992.14 ABK75608.1 - 8.3e-30 104.0 0.6 5.4e-29 101.3 0.6 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 ABK75608.1 - 3.3e-24 84.8 0.0 4.7e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 ABK75608.1 - 9.5e-11 41.8 0.3 3.3e-10 40.0 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ABK75608.1 - 2.2e-09 37.4 2.0 2e-05 24.3 0.3 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 ABK75608.1 - 4.3e-09 36.8 0.0 8.8e-06 26.2 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ABK75608.1 - 7.4e-09 35.4 2.4 2.3e-08 33.8 0.3 2.4 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 ABK75608.1 - 1.2e-08 34.6 0.1 0.0054 16.0 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ABK75608.1 - 3.5e-07 29.9 0.1 6.1e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ABK75608.1 - 3.7e-06 25.9 1.8 1.1e-05 24.4 0.1 2.3 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.24 ABK75608.1 - 3.3e-05 23.2 0.9 3.3e-05 23.2 0.9 2.4 2 1 0 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.19 ABK75608.1 - 4.3e-05 22.9 0.2 4.3e-05 22.9 0.2 2.0 2 0 0 2 2 2 1 FAD binding domain FMO-like PF00743.19 ABK75608.1 - 5.7e-05 21.7 0.0 0.00059 18.4 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like AlaDh_PNT_C PF01262.21 ABK75608.1 - 7.1e-05 22.2 0.0 0.0036 16.6 0.1 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 ABK75608.1 - 8.2e-05 23.0 0.9 0.026 14.9 0.1 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.17 ABK75608.1 - 0.00091 18.5 1.7 0.0011 18.2 0.0 1.9 3 0 0 3 3 2 1 Thi4 family K_oxygenase PF13434.6 ABK75608.1 - 0.0022 17.2 0.4 3 6.9 0.1 3.2 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 ABK75608.1 - 0.004 16.3 0.5 0.004 16.3 0.5 2.4 3 0 0 3 3 3 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 ABK75608.1 - 0.0097 15.8 0.1 0.017 15.0 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 ABK75608.1 - 0.012 16.2 0.0 1.5 9.5 0.1 2.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 ABK75608.1 - 0.023 14.7 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus YjeF_N PF03853.15 ABK75608.1 - 0.023 14.6 0.4 0.6 10.0 0.0 2.2 2 0 0 2 2 2 0 YjeF-related protein N-terminus Lycopene_cycl PF05834.12 ABK75608.1 - 0.027 13.5 0.2 0.049 12.7 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Shikimate_DH PF01488.20 ABK75608.1 - 0.04 14.0 0.0 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DJ-1_PfpI PF01965.24 ABK75608.1 - 0.043 13.6 1.5 4 7.2 0.1 3.2 2 1 1 3 3 3 0 DJ-1/PfpI family NAD_binding_9 PF13454.6 ABK75608.1 - 0.051 13.6 0.1 0.051 13.6 0.1 3.0 4 0 0 4 4 3 0 FAD-NAD(P)-binding AdoHcyase_NAD PF00670.21 ABK75608.1 - 0.085 12.9 0.2 4.7 7.2 0.1 2.4 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 ABK75608.1 - 0.093 12.1 0.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 ABK75608.1 - 0.12 11.9 1.4 0.13 11.8 0.1 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 ABK75608.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 ABK75608.1 - 0.18 10.6 0.3 0.38 9.5 0.3 1.5 1 0 0 1 1 1 0 Tryptophan halogenase Fer4_4 PF12800.7 ABK75608.1 - 4.3 8.1 8.1 0.49 11.0 0.9 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Bac_luciferase PF00296.20 ABK75609.1 - 1.7e-45 155.8 1.5 2e-45 155.6 1.5 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase FAD_oxidored PF12831.7 ABK75610.1 - 3.9e-101 339.5 2.0 4.5e-101 339.3 2.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ABK75610.1 - 1.3e-12 47.5 12.2 7.7e-09 35.1 7.1 2.2 1 1 1 2 2 2 2 FAD binding domain Thi4 PF01946.17 ABK75610.1 - 1.8e-08 33.9 3.6 2.9e-05 23.4 2.0 2.3 2 0 0 2 2 2 2 Thi4 family DAO PF01266.24 ABK75610.1 - 4e-08 33.2 12.9 1.9e-05 24.4 5.0 2.7 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ABK75610.1 - 7.4e-07 28.7 1.2 0.00072 18.9 1.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ABK75610.1 - 1.5e-06 27.7 1.6 0.00011 21.6 0.8 2.1 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 ABK75610.1 - 6.9e-06 25.0 2.9 3e-05 22.9 2.9 1.8 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 ABK75610.1 - 1.1e-05 25.9 1.1 0.068 13.7 1.6 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ABK75610.1 - 0.00036 20.7 4.4 0.00036 20.7 4.4 3.1 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ABK75610.1 - 0.0029 16.9 1.1 0.0051 16.1 1.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ABK75610.1 - 0.013 14.6 6.2 0.024 13.7 6.2 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 ABK75610.1 - 0.019 14.3 1.6 0.032 13.5 1.6 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 ABK75610.1 - 0.15 11.1 3.1 2 7.4 1.7 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein tRNA_U5-meth_tr PF05958.11 ABK75612.1 - 2.1e-10 40.1 0.0 1.1e-09 37.8 0.0 1.8 1 1 1 2 2 2 1 tRNA (Uracil-5-)-methyltransferase TRAM PF01938.20 ABK75612.1 - 4.5e-07 29.8 0.0 8.9e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 TRAM domain PCMT PF01135.19 ABK75612.1 - 6.4e-05 22.8 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 ABK75612.1 - 0.00098 19.8 0.1 0.0024 18.5 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ABK75612.1 - 0.0038 16.8 0.0 0.0064 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CmcI PF04989.12 ABK75612.1 - 0.0059 16.3 0.1 0.0097 15.6 0.1 1.3 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_31 PF13847.6 ABK75612.1 - 0.015 15.1 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 ABK75612.1 - 0.025 13.9 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family F420_oxidored PF03807.17 ABK75612.1 - 0.035 14.7 0.0 0.13 12.8 0.2 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_2 PF07992.14 ABK75613.1 - 1.1e-38 133.1 2.1 1.4e-38 132.8 2.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ABK75613.1 - 6e-16 58.8 1.8 5.1e-09 36.6 0.5 3.4 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ABK75613.1 - 2.9e-07 29.9 8.1 0.00022 20.4 2.1 3.2 2 1 1 3 3 3 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 ABK75613.1 - 2e-06 27.2 5.4 0.013 14.7 2.3 2.5 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 ABK75613.1 - 5.1e-06 26.3 6.9 0.0014 18.3 0.1 2.7 2 1 1 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 ABK75613.1 - 1.4e-05 24.0 1.4 0.026 13.2 0.0 2.6 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_7 PF13241.6 ABK75613.1 - 1.7e-05 25.2 1.1 0.026 15.0 0.0 2.6 2 0 0 2 2 2 2 Putative NAD(P)-binding TrkA_N PF02254.18 ABK75613.1 - 5.8e-05 23.3 1.9 0.016 15.4 0.0 2.7 2 0 0 2 2 2 1 TrkA-N domain Pyr_redox_3 PF13738.6 ABK75613.1 - 0.0001 21.7 2.0 0.03 13.6 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ABK75613.1 - 0.00053 19.4 6.2 0.12 11.7 3.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ABK75613.1 - 0.0016 18.6 6.5 0.049 13.9 0.1 3.0 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 ABK75613.1 - 0.0018 17.6 4.6 0.12 11.6 1.5 2.4 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 ABK75613.1 - 0.0045 16.1 4.4 0.027 13.5 0.0 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein Trp_halogenase PF04820.14 ABK75613.1 - 0.005 15.7 0.6 0.005 15.7 0.6 3.1 3 2 0 4 4 4 1 Tryptophan halogenase ApbA PF02558.16 ABK75613.1 - 0.0063 16.2 3.3 0.048 13.3 0.1 2.4 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 ABK75613.1 - 0.0077 15.5 8.5 0.21 10.8 0.1 2.9 2 1 1 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 ABK75613.1 - 0.0091 16.1 0.2 0.12 12.5 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 ABK75613.1 - 0.047 12.9 1.9 5.1 6.3 0.1 2.7 3 0 0 3 3 3 0 Thi4 family 3HCDH_N PF02737.18 ABK75613.1 - 0.048 13.5 2.5 1.3 8.9 0.6 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K_oxygenase PF13434.6 ABK75613.1 - 0.049 12.8 0.0 5.7 6.0 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 ABK75613.1 - 0.092 12.7 0.1 0.092 12.7 0.1 3.7 4 1 0 4 4 4 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 ABK75613.1 - 0.43 10.1 1.8 3 7.4 0.0 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TPR_12 PF13424.6 ABK75614.1 - 0.0041 17.4 19.3 0.051 13.9 1.7 5.5 3 1 4 7 7 7 4 Tetratricopeptide repeat TPR_MalT PF17874.1 ABK75614.1 - 0.0054 16.2 1.3 0.0054 16.2 1.3 3.6 3 1 1 4 4 4 1 MalT-like TPR region TPR_19 PF14559.6 ABK75614.1 - 0.012 16.1 12.8 5.6 7.6 0.0 5.1 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 ABK75614.1 - 0.08 13.6 0.4 0.08 13.6 0.4 8.2 8 2 1 9 9 9 0 Tetratricopeptide repeat TarH PF02203.15 ABK75614.1 - 0.097 12.6 0.1 22 4.9 0.0 2.8 2 0 0 2 2 2 0 Tar ligand binding domain homologue TPR_14 PF13428.6 ABK75614.1 - 0.41 11.6 30.3 1.8 9.6 0.9 6.8 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 ABK75614.1 - 1.1 9.5 10.0 68 3.9 0.2 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Hydrolase_4 PF12146.8 ABK75616.1 - 1.1e-11 44.5 0.4 2e-05 24.0 0.2 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 ABK75616.1 - 5.6e-11 42.3 0.1 5.2e-10 39.2 0.1 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 ABK75616.1 - 6e-08 32.8 1.4 3.4e-07 30.4 1.4 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 ABK75616.1 - 2.9e-07 30.4 0.4 6.1e-05 22.8 0.2 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK75616.1 - 1.2e-06 29.4 3.3 2.1e-06 28.5 3.3 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 ABK75616.1 - 1.4e-05 24.7 1.5 0.0024 17.4 1.5 2.8 1 1 0 1 1 1 1 Esterase PHB depolymerase FSH1 PF03959.13 ABK75616.1 - 0.00017 21.3 0.0 0.00025 20.8 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Esterase PF00756.20 ABK75616.1 - 0.017 14.8 0.0 0.046 13.4 0.0 1.8 1 1 0 1 1 1 0 Putative esterase COesterase PF00135.28 ABK75616.1 - 0.024 13.5 0.2 0.05 12.5 0.2 1.5 1 1 0 1 1 1 0 Carboxylesterase family DUF2974 PF11187.8 ABK75616.1 - 0.082 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Thioesterase PF00975.20 ABK75616.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain ThrE PF06738.12 ABK75617.1 - 8.6e-70 234.8 39.2 5.4e-65 219.1 13.9 2.1 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 ABK75617.1 - 8e-16 58.4 36.5 9.4e-15 54.9 14.2 2.2 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE Metallophos PF00149.28 ABK75618.1 - 1.5e-11 45.2 0.0 2.5e-11 44.5 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ABK75618.1 - 4.9e-06 26.8 0.0 7.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Peptidase_M20 PF01546.28 ABK75619.1 - 3.5e-37 128.1 0.6 3.5e-37 128.1 0.6 1.4 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ABK75619.1 - 2e-20 72.7 0.0 4.5e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain PRODH PF18327.1 ABK75619.1 - 0.85 9.9 5.7 0.23 11.7 0.6 2.6 2 0 0 2 2 2 0 Proline utilization A proline dehydrogenase N-terminal domain Ribosomal_L33 PF00471.20 ABK75620.1 - 9.5e-16 58.0 0.0 1.1e-15 57.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 Lactamase_B PF00753.27 ABK75621.1 - 3.2e-36 125.2 5.0 4.2e-36 124.8 5.0 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ABK75621.1 - 1e-07 31.7 0.1 1.3e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 ABK75621.1 - 0.0081 15.6 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Zincin_1 PF06262.11 ABK75622.1 - 1.1e-06 28.7 0.0 1.7e-06 28.1 0.0 1.4 1 1 0 1 1 1 1 Zincin-like metallopeptidase TetR_C_11 PF16859.5 ABK75623.1 - 3.4e-12 46.7 1.4 3.4e-12 46.7 1.4 1.9 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK75623.1 - 4.7e-07 29.5 0.7 1.1e-06 28.4 0.7 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family DUF3604 PF12228.8 ABK75623.1 - 0.067 11.6 0.0 0.084 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3604) Sigma70_ECF PF07638.11 ABK75623.1 - 0.096 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 ECF sigma factor PucR PF07905.11 ABK75624.1 - 1.3e-23 83.5 0.0 3.3e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 Purine catabolism regulatory protein-like family HTH_30 PF13556.6 ABK75624.1 - 2.6e-18 65.6 0.4 6e-18 64.4 0.4 1.7 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain DUF2089 PF09862.9 ABK75624.1 - 4.6e-07 29.9 0.0 9.1e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2089) HTH_8 PF02954.19 ABK75624.1 - 6e-05 22.8 0.2 0.00025 20.8 0.0 2.2 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family HTH_28 PF13518.6 ABK75624.1 - 0.011 15.8 0.0 0.056 13.6 0.0 2.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 ABK75624.1 - 0.048 13.5 0.0 0.17 11.7 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain HTH_50 PF18024.1 ABK75624.1 - 0.05 13.2 0.1 0.35 10.5 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_11 PF08279.12 ABK75624.1 - 0.057 13.4 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 HTH domain HTH_Tnp_ISL3 PF13542.6 ABK75624.1 - 0.26 10.7 0.0 0.26 10.7 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 Aldo_ket_red PF00248.21 ABK75625.1 - 5.9e-48 163.6 0.0 6.6e-46 156.8 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family SBP_bac_3 PF00497.20 ABK75627.1 - 3.3e-59 200.1 3.0 4.2e-59 199.7 3.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 BPD_transp_1 PF00528.22 ABK75627.1 - 8.9e-25 87.5 14.7 8.9e-25 87.5 14.7 1.7 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Lig_chan-Glu_bd PF10613.9 ABK75627.1 - 4.3e-08 33.4 0.1 3.1e-06 27.4 0.1 2.4 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site NMT1 PF09084.11 ABK75627.1 - 0.017 15.1 0.3 0.038 13.9 0.3 1.7 1 1 1 2 2 2 0 NMT1/THI5 like Phosphonate-bd PF12974.7 ABK75627.1 - 0.045 13.3 0.5 0.13 11.8 0.5 1.8 1 1 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Acyl-CoA_dh_C PF12806.7 ABK75628.1 - 3.2e-33 114.5 1.8 3.2e-33 114.5 1.8 1.9 2 0 0 2 2 2 1 Acetyl-CoA dehydrogenase C-terminal like Acyl-CoA_dh_M PF02770.19 ABK75628.1 - 3.7e-17 62.3 0.0 8.1e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 ABK75628.1 - 1.3e-14 54.7 2.7 5.3e-14 52.7 0.4 2.8 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain AcylCoA_DH_N PF12418.8 ABK75628.1 - 4.5e-09 36.2 0.1 9.8e-09 35.1 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase N terminal Acyl-CoA_dh_2 PF08028.11 ABK75628.1 - 0.005 17.1 0.0 0.057 13.7 0.0 2.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Form-deh_trans PF09163.11 ABK75629.1 - 0.036 13.8 1.7 0.047 13.5 1.7 1.1 1 0 0 1 1 1 0 Formate dehydrogenase N, transmembrane Peripla_BP_5 PF13433.6 ABK75630.1 - 7.2e-150 499.0 0.2 8.8e-150 498.7 0.2 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_6 PF13458.6 ABK75630.1 - 3.7e-84 283.3 1.5 4.6e-84 283.0 1.5 1.0 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 ABK75630.1 - 1.3e-13 50.8 0.0 1.6e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region LPAM_2 PF13627.6 ABK75630.1 - 0.36 10.7 2.2 0.7 9.8 2.2 1.5 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site Sugar_tr PF00083.24 ABK75631.1 - 1.6e-108 363.5 18.8 1.8e-108 363.3 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ABK75631.1 - 1.6e-31 109.5 39.4 1.6e-31 109.5 39.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 ABK75631.1 - 0.0069 15.3 15.4 0.13 11.1 1.8 2.5 2 1 0 2 2 2 2 MFS_1 like family TMEM240 PF15207.6 ABK75631.1 - 0.25 11.0 1.6 0.5 10.0 1.6 1.4 1 0 0 1 1 1 0 TMEM240 family SNN_transmemb PF09049.10 ABK75631.1 - 10 6.2 13.3 22 5.1 1.4 3.7 2 0 0 2 2 2 0 Stannin transmembrane Glyco_hydro_100 PF12899.7 ABK75632.1 - 0.00073 18.3 0.1 0.0011 17.7 0.1 1.2 1 0 0 1 1 1 1 Alkaline and neutral invertase AMP-binding PF00501.28 ABK75633.1 - 5.9e-75 252.4 0.0 7.1e-75 252.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK75633.1 - 0.29 12.1 2.3 0.37 11.8 0.2 2.4 3 0 0 3 3 3 0 AMP-binding enzyme C-terminal domain Fer2 PF00111.27 ABK75634.1 - 7.2e-09 35.5 1.4 1.2e-08 34.8 1.4 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain SnoaL_4 PF13577.6 ABK75636.1 - 9.8e-29 100.1 6.7 1.1e-28 99.9 6.7 1.0 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 ABK75636.1 - 6.8e-05 23.5 3.4 9.2e-05 23.0 3.3 1.3 1 1 0 1 1 1 1 SnoaL-like domain Lumazine_bd_2 PF12893.7 ABK75636.1 - 0.00015 22.4 0.3 0.00054 20.6 0.3 1.9 1 1 0 1 1 1 1 Putative lumazine-binding SnoaL_3 PF13474.6 ABK75636.1 - 0.00056 20.2 1.5 0.00078 19.7 1.5 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 ABK75636.1 - 0.0087 16.4 1.3 0.011 16.2 1.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.12 ABK75636.1 - 0.03 14.1 0.2 0.045 13.6 0.2 1.4 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase Scytalone_dh PF02982.14 ABK75636.1 - 0.05 13.4 0.1 0.066 13.0 0.1 1.3 1 0 0 1 1 1 0 Scytalone dehydratase Ring_hydroxyl_B PF00866.18 ABK75636.1 - 0.051 13.6 0.7 0.083 13.0 0.1 1.6 2 0 0 2 2 2 0 Ring hydroxylating beta subunit AAA_16 PF13191.6 ABK75637.1 - 1.3e-16 61.5 1.3 1.3e-16 61.5 1.3 4.0 3 1 0 4 4 3 1 AAA ATPase domain GerE PF00196.19 ABK75637.1 - 1.3e-14 53.5 0.0 2.7e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family DUF2791 PF10923.8 ABK75637.1 - 0.00016 20.7 0.0 0.00035 19.5 0.0 1.5 1 0 0 1 1 1 1 P-loop Domain of unknown function (DUF2791) AAA_22 PF13401.6 ABK75637.1 - 0.0004 20.7 0.0 0.0015 18.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 ABK75637.1 - 0.00041 20.3 0.9 0.044 13.7 0.2 2.9 2 2 0 2 2 2 1 NACHT domain HTH_23 PF13384.6 ABK75637.1 - 0.00047 19.9 2.4 0.0083 15.9 0.0 3.6 3 0 0 3 3 3 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 ABK75637.1 - 0.022 14.4 0.1 1.2 8.8 0.0 3.5 3 0 0 3 3 3 0 Sigma-70, region 4 DUF4262 PF14081.6 ABK75637.1 - 0.025 14.8 0.1 4.4 7.5 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4262) HTH_38 PF13936.6 ABK75637.1 - 0.066 13.0 0.1 2.1 8.2 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain DUF2877 PF11392.8 ABK75637.1 - 0.066 13.9 0.2 23 5.8 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2877) DUF5624 PF18538.1 ABK75637.1 - 0.12 12.5 0.2 4 7.5 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5624) TsaE PF02367.17 ABK75637.1 - 0.14 12.2 0.0 0.41 10.7 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 ABK75637.1 - 0.26 10.4 0.0 1.1 8.4 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.6 ABK75637.1 - 3.4 8.0 6.1 2 8.7 0.1 3.1 3 1 0 3 3 2 0 AAA domain DUF3613 PF12266.8 ABK75638.1 - 0.072 12.9 3.4 0.47 10.3 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3613) His_Phos_1 PF00300.22 ABK75639.1 - 3.9e-43 147.4 0.4 4.4e-43 147.2 0.4 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ribosomal_S10 PF00338.22 ABK75640.1 - 1.1e-34 118.5 0.1 1.2e-34 118.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF384 PF04064.13 ABK75640.1 - 0.03 14.2 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF384) PriA_C PF18074.1 ABK75640.1 - 0.039 14.8 0.0 0.38 11.6 0.0 2.0 1 1 0 2 2 2 0 Primosomal protein N C-terminal domain PLDc_2 PF13091.6 ABK75641.1 - 5.9e-12 45.6 0.0 1.5e-06 28.1 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 ABK75641.1 - 6.2e-06 26.2 1.1 0.084 13.1 0.1 3.0 2 1 0 2 2 2 2 Phospholipase D Active site motif Cupin_2 PF07883.11 ABK75642.1 - 6.5e-06 25.8 0.0 8.1e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Cupin domain PGM_PMM_IV PF00408.20 ABK75644.1 - 0.13 12.5 0.0 0.13 12.5 0.0 2.5 2 1 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain Acetyltransf_9 PF13527.7 ABK75645.1 - 7.1e-27 94.0 0.0 1.1e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_17 PF17668.1 ABK75645.1 - 5.1e-22 78.9 0.4 1.1e-21 77.8 0.4 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SCP2_2 PF13530.6 ABK75645.1 - 2.7e-12 47.0 0.0 5.4e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Sterol carrier protein domain Acetyltransf_1 PF00583.25 ABK75645.1 - 0.00069 19.8 0.0 0.0014 18.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 ABK75645.1 - 0.025 14.6 0.0 0.06 13.3 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_7 PF13508.7 ABK75645.1 - 0.042 14.3 0.0 0.076 13.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Bac_luciferase PF00296.20 ABK75646.1 - 1.2e-42 146.5 0.7 1.5e-42 146.1 0.7 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Phage_integrase PF00589.22 ABK75647.1 - 6.3e-18 65.1 0.0 1.1e-17 64.4 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 ABK75647.1 - 0.0024 18.1 0.1 0.029 14.7 0.1 2.9 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 ABK75647.1 - 0.12 12.9 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain DUF308 PF03729.13 ABK75648.1 - 2.2e-05 24.7 8.6 2.2e-05 24.7 8.6 3.4 2 1 1 3 3 3 2 Short repeat of unknown function (DUF308) MFS_1 PF07690.16 ABK75649.1 - 2e-26 92.8 49.7 2e-26 92.8 49.7 2.8 1 1 2 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK75649.1 - 4.4e-20 72.0 28.9 3.1e-18 65.9 7.4 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 ABK75649.1 - 3.5e-09 35.7 27.4 9.6e-07 27.7 8.7 3.0 2 1 1 3 3 3 3 MFS/sugar transport protein TetR_N PF00440.23 ABK75650.1 - 4.8e-16 58.3 0.1 8.6e-16 57.5 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 ABK75650.1 - 5.4e-06 26.6 1.6 1.4e-05 25.2 0.0 2.3 1 1 2 3 3 3 1 BetI-type transcriptional repressor, C-terminal TetR_C_29 PF17938.1 ABK75650.1 - 0.00017 21.6 0.0 0.00064 19.8 0.0 1.8 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_11 PF16859.5 ABK75650.1 - 0.00049 20.4 1.0 0.00049 20.4 1.0 2.4 1 1 2 3 3 3 1 Tetracyclin repressor-like, C-terminal domain TetR_C_24 PF17932.1 ABK75650.1 - 0.0036 17.6 0.0 0.0066 16.7 0.0 1.6 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_14 PF17754.1 ABK75650.1 - 0.016 15.1 0.0 0.055 13.4 0.0 1.9 2 1 0 2 2 2 0 MftR C-terminal domain TetR_C_21 PF17926.1 ABK75650.1 - 0.019 15.1 0.0 0.046 13.9 0.0 1.7 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF1488 PF07369.11 ABK75650.1 - 0.075 13.0 0.1 4.1 7.5 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1488) HTH_3 PF01381.22 ABK75651.1 - 1.7e-10 40.8 0.0 2e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 ABK75651.1 - 3.9e-10 39.9 0.0 5.3e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 ABK75651.1 - 2.5e-06 27.4 0.0 3e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 ABK75651.1 - 1.2e-05 25.7 0.0 1.7e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 ABK75651.1 - 0.0023 17.7 0.0 0.0035 17.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 ABK75651.1 - 0.054 13.2 0.0 0.32 10.7 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_24 PF13412.6 ABK75651.1 - 0.057 13.0 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 ABK75651.1 - 0.085 12.7 0.0 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain HTH_38 PF13936.6 ABK75651.1 - 0.09 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Dioxygenase_C PF00775.21 ABK75652.1 - 5.9e-60 201.8 0.0 7.4e-60 201.5 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 ABK75652.1 - 1.7e-17 63.0 0.9 2.4e-17 62.5 0.9 1.2 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 ABK75652.1 - 0.006 16.8 0.0 0.035 14.4 0.0 2.2 2 1 0 2 2 2 1 Carboxypeptidase regulatory-like domain Aminotran_3 PF00202.21 ABK75653.1 - 1.2e-74 251.4 0.0 1.6e-74 251.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III APH PF01636.23 ABK75653.1 - 1.2e-17 64.6 2.0 2.8e-17 63.4 2.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family AMP-binding PF00501.28 ABK75654.1 - 1.6e-82 277.4 0.0 2e-82 277.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK75654.1 - 1.5e-23 83.5 0.9 3.9e-23 82.2 0.9 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 ABK75654.1 - 0.0088 16.3 0.0 0.022 15.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DAO PF01266.24 ABK75655.1 - 9.3e-51 173.5 5.7 1.1e-50 173.2 5.7 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ABK75655.1 - 1.8e-05 24.2 1.0 3.3e-05 23.3 1.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ABK75655.1 - 2.2e-05 24.6 1.8 5.4e-05 23.3 1.8 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ABK75655.1 - 0.0002 20.6 4.4 0.00042 19.5 4.1 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 ABK75655.1 - 0.00053 20.0 1.3 0.26 11.2 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.17 ABK75655.1 - 0.00063 19.0 0.3 0.0012 18.2 0.3 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 ABK75655.1 - 0.00089 18.4 3.1 0.56 9.2 2.9 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox PF00070.27 ABK75655.1 - 0.00097 19.7 1.2 0.0025 18.3 1.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ABK75655.1 - 0.0027 16.5 0.3 0.14 10.8 0.7 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 ABK75655.1 - 0.0036 16.6 1.6 0.023 13.9 1.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 ABK75655.1 - 0.0078 15.7 0.1 0.021 14.3 0.1 1.6 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Pyr_redox_3 PF13738.6 ABK75655.1 - 0.027 13.7 0.1 0.11 11.8 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 ABK75655.1 - 0.041 13.5 0.9 0.18 11.4 0.9 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 ABK75655.1 - 0.047 13.0 2.6 0.11 11.7 2.5 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 ABK75655.1 - 0.1 12.1 0.5 0.2 11.2 0.5 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_halogenase PF04820.14 ABK75655.1 - 0.24 10.2 1.8 12 4.6 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.18 ABK75655.1 - 0.42 10.5 2.1 0.71 9.7 2.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Condensation PF00668.20 ABK75656.1 - 1.4e-11 43.7 0.0 1.8e-09 36.8 0.0 2.0 2 0 0 2 2 2 2 Condensation domain AATase PF07247.12 ABK75656.1 - 0.00082 18.0 0.0 0.18 10.4 0.0 3.1 3 1 0 3 3 3 2 Alcohol acetyltransferase Na_Ala_symp PF01235.17 ABK75657.1 - 4.4e-150 500.4 33.2 5.6e-150 500.0 33.2 1.1 1 0 0 1 1 1 1 Sodium:alanine symporter family SieB PF14163.6 ABK75657.1 - 0.75 9.3 2.7 2.4 7.6 2.7 1.9 1 0 0 1 1 1 0 Super-infection exclusion protein B DctQ PF04290.12 ABK75659.1 - 8e-29 100.2 11.4 1.2e-28 99.7 11.4 1.3 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporters, DctQ component TerC PF03741.16 ABK75659.1 - 0.28 10.8 3.1 0.25 11.0 1.4 1.8 1 1 1 2 2 2 0 Integral membrane protein TerC family Trp_oprn_chp PF09534.10 ABK75659.1 - 0.61 9.9 7.7 2.1 8.1 0.2 2.9 2 1 1 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Tetraspanin PF00335.20 ABK75659.1 - 1.3 8.7 6.4 1.5 8.5 0.6 2.0 2 0 0 2 2 2 0 Tetraspanin family DUF373 PF04123.13 ABK75659.1 - 8.7 5.7 6.1 3.8 6.9 3.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF373) T7SS_ESX1_EccB PF05108.13 ABK75660.1 - 2.8e-181 603.3 3.3 3.2e-181 603.1 3.3 1.0 1 0 0 1 1 1 1 Type VII secretion system ESX-1, transport TM domain B HycI PF01750.18 ABK75661.1 - 2.1e-16 59.9 0.0 3.2e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Hydrogenase maturation protease SBP_bac_6 PF13343.6 ABK75662.1 - 3.7e-25 88.8 0.2 4.8e-25 88.4 0.2 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 ABK75662.1 - 8.2e-25 88.2 0.3 1.2e-24 87.7 0.3 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 ABK75662.1 - 8.2e-22 78.1 1.8 1.2e-21 77.5 1.8 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 ABK75662.1 - 5.2e-21 75.9 5.2 6.8e-21 75.5 5.2 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Peptidase_S13 PF02113.15 ABK75663.1 - 7.8e-102 341.3 10.8 1.1e-62 212.2 3.2 2.1 1 1 1 2 2 2 2 D-Ala-D-Ala carboxypeptidase 3 (S13) family Beta-lactamase2 PF13354.6 ABK75663.1 - 0.011 15.4 1.7 1.8 8.1 0.0 3.1 2 1 0 2 2 2 0 Beta-lactamase enzyme family DUF3445 PF11927.8 ABK75664.1 - 1.3e-44 152.5 0.0 1.8e-44 152.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) EamA PF00892.20 ABK75665.1 - 8.2e-19 68.1 27.0 1.8e-09 37.9 15.9 2.0 2 0 0 2 2 2 2 EamA-like transporter family 7TMR-DISM_7TM PF07695.11 ABK75665.1 - 1.4 8.7 8.6 0.082 12.8 1.0 2.2 1 1 1 2 2 2 0 7TM diverse intracellular signalling TcdA_TcdB_pore PF12920.7 ABK75665.1 - 6.1 5.0 5.1 9.5 4.3 5.1 1.2 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain adh_short_C2 PF13561.6 ABK75666.1 - 2.4e-43 148.4 0.4 3e-43 148.1 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK75666.1 - 7.1e-31 107.2 0.6 8.1e-31 107.0 0.6 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK75666.1 - 1.2e-06 28.6 0.2 1.5e-06 28.3 0.2 1.2 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.15 ABK75666.1 - 0.0013 18.6 0.2 0.002 18.0 0.2 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus Peptidase_U32 PF01136.19 ABK75666.1 - 0.13 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase family U32 Rhodanese PF00581.20 ABK75667.1 - 1.3e-19 70.7 0.0 3e-12 47.0 0.0 2.5 2 0 0 2 2 2 2 Rhodanese-like domain Lactamase_B PF00753.27 ABK75667.1 - 3.1e-11 43.7 2.9 1.2e-10 41.7 2.9 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 ABK75667.1 - 0.06 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain DDE_Tnp_ISL3 PF01610.17 ABK75668.1 - 1.6e-64 217.9 0.0 2.1e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Transposase zf-ISL3 PF14690.6 ABK75668.1 - 1.1e-09 38.8 4.6 1.8e-09 38.1 2.5 2.5 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HTH_Tnp_ISL3 PF13542.6 ABK75668.1 - 2.4e-08 33.2 1.6 7e-08 31.8 1.6 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 VWA_N2 PF16164.5 ABK75669.1 - 2.2 8.5 5.2 1.6 8.9 2.5 1.9 2 0 0 2 2 2 0 VWA N-terminal FAP PF07174.11 ABK75670.1 - 0.043 13.3 12.6 0.051 13.0 12.6 1.0 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) SSP160 PF06933.11 ABK75670.1 - 0.23 9.6 12.5 0.25 9.5 12.5 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MGC-24 PF05283.11 ABK75670.1 - 1 9.8 5.6 1.1 9.7 5.6 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Dicty_REP PF05086.12 ABK75670.1 - 1.7 6.5 3.0 1.5 6.7 3.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TPR_21 PF09976.9 ABK75671.1 - 3.5 7.3 5.4 15 5.2 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain CPBP PF02517.16 ABK75672.1 - 8.9e-16 58.1 5.3 8.9e-16 58.1 5.3 2.8 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease HycI PF01750.18 ABK75673.1 - 3e-09 36.8 0.0 3.3e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Hydrogenase maturation protease HATPase_c_3 PF13589.6 ABK75674.1 - 5.4e-09 36.0 0.0 2.5e-06 27.4 0.0 2.3 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DDR PF08841.10 ABK75675.1 - 1.6e-85 287.0 1.1 1.2e-84 284.1 1.1 2.1 1 1 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain DDR_swiveling PF18427.1 ABK75675.1 - 1.6e-27 96.5 0.3 3.2e-27 95.5 0.3 1.4 1 0 0 1 1 1 1 DD-reactivating factor swiveling domain FtsA PF14450.6 ABK75675.1 - 3.2e-06 27.5 0.7 0.00039 20.8 0.0 2.6 2 1 0 2 2 2 2 Cell division protein FtsA Hydantoinase_A PF01968.18 ABK75675.1 - 0.0017 17.7 0.6 0.41 9.9 0.0 2.4 1 1 1 2 2 2 2 Hydantoinase/oxoprolinase GMC_oxred_C PF05199.13 ABK75676.1 - 1.8e-11 44.8 0.0 3.3e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 ABK75676.1 - 1e-10 41.8 0.9 8e-10 38.8 0.9 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase GMC_oxred_N PF00732.19 ABK75676.1 - 4.2e-08 32.9 0.0 1.4e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ABK75676.1 - 1.1e-06 28.0 0.1 7.2e-05 22.0 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 ABK75676.1 - 6.4e-05 22.3 0.0 0.00082 18.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ABK75676.1 - 0.00012 22.3 0.4 0.00044 20.4 0.3 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 ABK75676.1 - 0.0019 17.5 0.0 0.019 14.2 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Fer4_9 PF13187.6 ABK75676.1 - 0.035 14.3 0.1 0.067 13.4 0.1 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain Pyr_redox PF00070.27 ABK75676.1 - 0.059 13.9 0.0 0.16 12.6 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ABK75676.1 - 0.083 12.0 0.0 1.3 8.0 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Fer4_10 PF13237.6 ABK75676.1 - 0.088 12.9 0.3 0.15 12.2 0.3 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 ABK75676.1 - 0.091 12.9 0.2 0.16 12.1 0.2 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4 PF00037.27 ABK75676.1 - 0.11 12.4 3.0 0.19 11.6 3.0 1.3 1 0 0 1 1 1 0 4Fe-4S binding domain HI0933_like PF03486.14 ABK75676.1 - 0.19 10.4 0.0 0.45 9.2 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein Fer4_4 PF12800.7 ABK75676.1 - 0.66 10.6 3.3 1.1 9.9 3.3 1.3 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_3 PF12798.7 ABK75676.1 - 0.76 10.8 4.0 1.3 10.2 4.0 1.4 1 0 0 1 1 1 0 4Fe-4S binding domain Abhydrolase_4 PF08386.10 ABK75677.1 - 9.4e-20 70.7 0.0 1.9e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 ABK75677.1 - 8.6e-14 51.8 0.0 3.7e-13 49.7 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ABK75677.1 - 0.0015 17.8 0.0 0.3 10.3 0.0 2.9 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Ndr PF03096.14 ABK75677.1 - 0.019 13.7 0.0 0.029 13.1 0.0 1.2 1 0 0 1 1 1 0 Ndr family BPD_transp_1 PF00528.22 ABK75678.1 - 1.1e-31 110.0 31.9 2e-17 63.6 11.2 3.3 4 0 0 4 4 4 2 Binding-protein-dependent transport system inner membrane component TraL PF07178.11 ABK75678.1 - 0.35 11.4 0.1 0.35 11.4 0.1 4.5 6 0 0 6 6 6 0 TraL protein VIT1 PF01988.19 ABK75679.1 - 1.1e-60 205.2 9.5 1.3e-60 205.0 9.5 1.0 1 0 0 1 1 1 1 VIT family AlaDh_PNT_C PF01262.21 ABK75679.1 - 0.028 13.7 0.4 0.028 13.7 0.4 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain MerE PF05052.12 ABK75679.1 - 0.47 10.4 5.6 10 6.1 2.1 2.4 2 0 0 2 2 2 0 MerE protein DUF3267 PF11667.8 ABK75679.1 - 1 9.7 5.5 0.27 11.6 2.2 1.6 2 0 0 2 2 2 0 Putative zincin peptidase DUF4781 PF16013.5 ABK75679.1 - 6.3 5.5 6.8 0.39 9.5 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4781) NMO PF03060.15 ABK75680.1 - 1.5e-26 93.6 4.1 9.7e-24 84.3 0.9 2.2 1 1 1 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 ABK75680.1 - 6.4e-06 25.4 0.0 1.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 ABK75680.1 - 3.7e-05 22.9 3.5 3.7e-05 22.9 3.5 1.5 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 ABK75680.1 - 0.021 14.3 0.1 0.054 12.9 0.0 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein ThiG PF05690.14 ABK75680.1 - 0.085 12.2 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG CPSase_sm_chain PF00988.22 ABK75681.1 - 7.7e-49 164.8 0.0 1.3e-48 164.0 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 ABK75681.1 - 4.5e-39 134.2 0.0 6.2e-39 133.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ABK75681.1 - 2.6e-08 33.9 0.1 8.7e-06 25.6 0.1 2.2 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 ABK75681.1 - 0.017 14.9 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family 4HBT PF03061.22 ABK75683.1 - 1.5e-13 50.9 0.4 2.1e-13 50.4 0.4 1.1 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 ABK75683.1 - 0.0008 19.7 0.0 0.00088 19.6 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.6 ABK75683.1 - 0.081 13.1 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) AMP-binding PF00501.28 ABK75684.1 - 1.6e-66 224.7 0.0 2.3e-66 224.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 ABK75684.1 - 4.1e-55 186.7 0.0 6e-55 186.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 ABK75684.1 - 3.8e-08 33.5 0.3 1.1e-07 32.1 0.3 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 ABK75684.1 - 2.3e-07 30.5 0.0 6.2e-07 29.1 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 ABK75684.1 - 0.0001 23.2 0.0 0.00046 21.1 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 ABK75684.1 - 0.0045 16.0 0.0 0.038 13.0 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Esterase PF00756.20 ABK75685.1 - 1.7e-46 158.9 1.6 2e-46 158.7 1.6 1.0 1 0 0 1 1 1 1 Putative esterase MlaD PF02470.20 ABK75686.1 - 2.6e-15 56.5 0.3 5.5e-15 55.4 0.3 1.5 1 0 0 1 1 1 1 MlaD protein Mce4_CUP1 PF11887.8 ABK75686.1 - 7.1e-05 22.4 1.4 9.9e-05 21.9 1.4 1.1 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative DASH_Dad2 PF08654.10 ABK75686.1 - 0.053 14.0 0.4 2.2 8.8 0.1 2.2 1 1 1 2 2 2 0 DASH complex subunit Dad2 IpaC_SipC PF09599.10 ABK75686.1 - 0.053 13.0 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 Salmonella-Shigella invasin protein C (IpaC_SipC) Collagen_mid PF15984.5 ABK75686.1 - 0.057 13.2 0.6 0.094 12.4 0.6 1.3 1 0 0 1 1 1 0 Bacterial collagen, middle region CagA PF03507.13 ABK75686.1 - 0.16 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 CagA exotoxin DUF1664 PF07889.12 ABK75686.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 ABK75686.1 - 0.3 11.4 3.1 7.2 6.9 0.5 3.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 ABK75686.1 - 2.1 8.9 4.2 1.3e+02 3.2 4.2 2.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein PseudoU_synth_2 PF00849.22 ABK75687.1 - 4.3e-23 82.2 0.0 5.4e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase SecY PF00344.20 ABK75688.1 - 2.7e-113 378.3 17.8 3.2e-113 378.0 17.8 1.1 1 0 0 1 1 1 1 SecY translocase TetR_C_11 PF16859.5 ABK75689.1 - 1.3e-17 64.1 6.5 1.3e-17 64.1 6.5 2.0 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK75689.1 - 6.9e-15 54.6 0.6 6.9e-15 54.6 0.6 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_Tnp_1_2 PF13022.6 ABK75689.1 - 0.0091 16.1 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix of insertion element transposase ROK PF00480.20 ABK75692.1 - 4.7e-25 88.7 0.0 5.3e-25 88.5 0.0 1.0 1 0 0 1 1 1 1 ROK family CoA_transf_3 PF02515.17 ABK75693.1 - 1.1e-165 551.2 0.0 3.3e-97 325.9 0.0 2.0 2 0 0 2 2 2 2 CoA-transferase family III Transposase_mut PF00872.18 ABK75694.1 - 4.1e-64 216.8 0.0 5e-64 216.5 0.0 1.1 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.9 ABK75694.1 - 2.8e-07 30.8 0.0 6.2e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Ribosomal_S24e PF01282.19 ABK75694.1 - 0.042 13.8 0.1 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein S24e Leuk-A4-hydro_C PF09127.11 ABK75694.1 - 0.068 13.3 0.1 5.2 7.2 0.0 2.5 2 0 0 2 2 2 0 Leukotriene A4 hydrolase, C-terminal DUF150 PF02576.17 ABK75695.1 - 3.5e-12 46.6 0.0 6.4e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 RimP N-terminal domain DUF150_C PF17384.2 ABK75695.1 - 2.8e-09 37.0 0.4 5.2e-09 36.1 0.2 1.6 2 0 0 2 2 2 1 RimP C-terminal SH3 domain Phage_sheath_1N PF17481.2 ABK75695.1 - 0.025 15.0 0.1 0.15 12.5 0.0 2.0 2 0 0 2 2 2 0 Phage tail sheath protein beta-sandwich domain LysR_substrate PF03466.20 ABK75696.1 - 1.3e-24 86.7 3.1 2.1e-24 86.1 3.1 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 ABK75696.1 - 1.6e-14 53.5 0.5 3.4e-14 52.5 0.5 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 ABK75696.1 - 0.058 13.3 0.7 0.058 13.3 0.7 2.1 2 0 0 2 2 2 0 MarR family GDE_N_bis PF14742.6 ABK75698.1 - 3.9e-37 127.7 0.0 5.9e-37 127.1 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of (some) glycogen debranching enzymes GDE_C PF06202.14 ABK75698.1 - 9.5e-13 47.8 0.0 5.4e-12 45.3 0.0 1.9 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Bac_rhamnosid6H PF17389.2 ABK75698.1 - 0.00019 20.8 0.0 0.00027 20.3 0.0 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Trehalase PF01204.18 ABK75698.1 - 0.0069 15.3 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Trehalase DUF608 PF04685.13 ABK75698.1 - 0.081 12.1 0.1 0.22 10.7 0.1 1.4 1 1 0 1 1 1 0 Glycosyl-hydrolase family 116, catalytic region Glyco_hydro_100 PF12899.7 ABK75698.1 - 0.11 11.1 0.0 3.4 6.2 0.0 2.1 2 0 0 2 2 2 0 Alkaline and neutral invertase TetR_C_11 PF16859.5 ABK75699.1 - 1.6e-25 89.7 9.2 1.6e-25 89.7 9.2 1.9 3 0 0 3 3 3 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK75699.1 - 9e-09 35.0 0.0 2.7e-08 33.5 0.0 1.9 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family DUF4110 PF13422.6 ABK75699.1 - 0.012 15.7 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) HTH_IclR PF09339.10 ABK75699.1 - 0.021 14.6 0.0 0.065 13.0 0.0 1.9 1 0 0 1 1 1 0 IclR helix-turn-helix domain Sigma70_ECF PF07638.11 ABK75699.1 - 0.05 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 ECF sigma factor TetR_C_16 PF17920.1 ABK75699.1 - 0.055 13.7 0.4 0.055 13.7 0.4 2.5 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain TetR_C_7 PF14246.6 ABK75699.1 - 0.062 13.3 4.2 0.18 11.8 4.2 1.8 1 1 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal domain HTH_23 PF13384.6 ABK75699.1 - 0.064 13.1 0.1 0.2 11.5 0.1 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_7 PF02796.15 ABK75699.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase LacI PF00356.21 ABK75699.1 - 0.14 11.9 1.3 0.24 11.2 0.2 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family TetR_C_6 PF13977.6 ABK75699.1 - 5.9 7.1 18.5 5.4 7.3 12.7 3.1 1 1 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal Polysacc_deac_1 PF01522.21 ABK75700.1 - 3.6e-18 65.7 0.0 5.6e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 ABK75700.1 - 6.6e-08 32.5 0.0 1.4e-07 31.4 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) FGGY_N PF00370.21 ABK75701.1 - 1.4e-35 123.0 0.0 2.2e-35 122.4 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 ABK75701.1 - 6.2e-32 110.9 0.3 1.1e-31 110.2 0.3 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain NHase_beta PF02211.15 ABK75702.1 - 1.2e-57 195.4 2.5 1.4e-57 195.2 2.5 1.0 1 0 0 1 1 1 1 Nitrile hydratase beta subunit DUF3349 PF11829.8 ABK75703.1 - 2.9e-32 111.3 0.1 3.3e-32 111.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3349) Glycos_trans_3N PF02885.17 ABK75703.1 - 0.00018 21.3 0.6 0.13 12.1 0.1 2.2 1 1 1 2 2 2 2 Glycosyl transferase family, helical bundle domain FIVAR PF07554.13 ABK75703.1 - 0.011 16.4 0.6 0.45 11.3 0.1 2.1 1 1 1 2 2 2 0 FIVAR domain Fer2_BFD PF04324.15 ABK75703.1 - 0.093 13.1 0.6 1.3 9.4 0.1 2.1 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain DUF2922 PF11148.8 ABK75703.1 - 0.12 12.1 1.4 20 5.0 0.4 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2922) Phenol_Hydrox PF02332.18 ABK75704.1 - 1.5e-57 194.8 0.1 2.2e-57 194.3 0.1 1.3 1 0 0 1 1 1 1 Methane/Phenol/Toluene Hydroxylase COesterase PF00135.28 ABK75705.1 - 2.3e-76 257.7 0.0 8.7e-68 229.4 0.0 2.2 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 ABK75705.1 - 2.8e-14 53.5 0.7 5e-14 52.7 0.7 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 ABK75705.1 - 0.014 14.3 0.0 0.056 12.3 0.0 2.0 1 1 0 1 1 1 0 Chlorophyllase enzyme Esterase PF00756.20 ABK75705.1 - 0.031 13.9 0.2 0.39 10.3 0.1 2.1 2 0 0 2 2 2 0 Putative esterase MgsA_C PF12002.8 ABK75706.1 - 1.1e-69 233.6 0.1 1.7e-69 233.1 0.1 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 ABK75706.1 - 6.4e-26 90.5 1.0 1.5e-25 89.3 0.2 2.1 2 0 0 2 2 1 1 AAA C-terminal domain AAA PF00004.29 ABK75706.1 - 9.2e-16 58.5 0.1 2.9e-15 56.8 0.1 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 ABK75706.1 - 3.5e-13 49.6 0.0 7.6e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 ABK75706.1 - 9.5e-10 38.6 0.4 2.6e-08 33.9 0.3 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ABK75706.1 - 3.2e-07 30.9 6.1 0.00026 21.4 0.3 3.0 1 1 2 3 3 3 2 AAA ATPase domain Sigma54_activat PF00158.26 ABK75706.1 - 4e-07 29.9 0.1 0.013 15.2 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 ABK75706.1 - 1.6e-06 28.3 0.0 3.5e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.6 ABK75706.1 - 4.7e-06 26.9 1.2 0.016 15.5 0.1 2.6 1 1 1 2 2 2 2 AAA domain Mg_chelatase PF01078.21 ABK75706.1 - 6.7e-06 25.6 3.9 0.0065 15.9 0.1 2.6 2 1 0 3 3 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 ABK75706.1 - 3.9e-05 23.5 0.0 7.3e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 ABK75706.1 - 9.7e-05 22.9 0.0 0.00017 22.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 ABK75706.1 - 0.00026 20.3 0.3 0.0045 16.2 0.1 2.3 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_30 PF13604.6 ABK75706.1 - 0.00026 20.8 4.5 0.0023 17.7 4.5 2.4 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta2 PF13177.6 ABK75706.1 - 0.00031 20.6 0.0 0.0043 16.9 0.0 2.1 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_3 PF07726.11 ABK75706.1 - 0.00043 20.2 2.4 0.0031 17.4 0.2 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 ABK75706.1 - 0.0012 18.4 4.2 0.0014 18.2 0.5 2.7 2 2 1 3 3 3 1 AAA domain AAA_14 PF13173.6 ABK75706.1 - 0.0016 18.4 0.0 0.0028 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 ABK75706.1 - 0.0017 18.3 0.7 0.2 11.5 0.0 2.3 1 1 1 2 2 2 1 NACHT domain AAA_24 PF13479.6 ABK75706.1 - 0.0017 18.1 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ABK75706.1 - 0.0029 17.9 1.9 0.6 10.4 0.3 2.5 1 1 1 2 2 2 1 AAA domain ResIII PF04851.15 ABK75706.1 - 0.003 17.6 0.6 0.066 13.2 0.1 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_33 PF13671.6 ABK75706.1 - 0.004 17.3 0.0 0.0096 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain MCM PF00493.23 ABK75706.1 - 0.0041 16.3 0.0 0.0075 15.4 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain DUF815 PF05673.13 ABK75706.1 - 0.005 16.0 0.0 0.0092 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 ABK75706.1 - 0.0084 16.5 0.0 0.018 15.4 0.0 1.6 1 1 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 ABK75706.1 - 0.012 15.9 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 ABK75706.1 - 0.014 14.6 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_2 PF07724.14 ABK75706.1 - 0.02 15.0 0.1 0.063 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.12 ABK75706.1 - 0.031 13.6 0.0 0.073 12.3 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DUF4862 PF16154.5 ABK75706.1 - 0.039 13.3 2.1 0.23 10.8 0.0 2.4 3 0 0 3 3 2 0 Domain of unknown function (DUF4862) AAA_13 PF13166.6 ABK75706.1 - 0.041 12.5 0.0 0.059 12.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 ABK75706.1 - 0.052 12.6 0.0 0.084 11.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase_2 PF01637.18 ABK75706.1 - 0.06 13.3 0.2 2.4 8.0 0.0 2.2 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 ABK75706.1 - 0.081 12.8 0.4 0.42 10.5 0.1 2.0 1 1 1 2 2 2 0 NTPase ABC_tran PF00005.27 ABK75706.1 - 0.09 13.3 0.0 0.19 12.3 0.0 1.7 1 1 0 1 1 1 0 ABC transporter TsaE PF02367.17 ABK75706.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 ABK75706.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 ABK75706.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ABK75706.1 - 0.25 11.8 0.0 0.38 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain CoA_transf_3 PF02515.17 ABK75707.1 - 9.6e-126 419.8 0.0 1.1e-125 419.6 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Phage-tail_3 PF13550.6 ABK75708.1 - 0.039 13.8 0.4 0.084 12.7 0.4 1.5 1 0 0 1 1 1 0 Putative phage tail protein Cation_ATPase_C PF00689.21 ABK75708.1 - 0.21 11.3 3.8 0.53 10.0 3.8 1.7 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus ABC2_membrane_5 PF13346.6 ABK75708.1 - 1.6 8.3 5.7 0.21 11.1 1.1 1.7 1 1 1 2 2 2 0 ABC-2 family transporter protein MIG-14_Wnt-bd PF06664.12 ABK75708.1 - 1.9 7.6 4.1 5.5 6.1 4.1 1.7 1 1 0 1 1 1 0 Wnt-binding factor required for Wnt secretion DUF4293 PF14126.6 ABK75708.1 - 2.5 8.4 5.7 6.8 6.9 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) CDP-OH_P_transf PF01066.21 ABK75709.1 - 1.9e-12 47.8 0.4 1.9e-12 47.8 0.4 2.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Acyl-CoA_dh_2 PF08028.11 ABK75710.1 - 6.4e-16 58.8 17.1 6.4e-16 58.8 17.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ABK75710.1 - 1e-12 48.1 0.0 4.6e-12 46.0 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 ABK75710.1 - 1.2e-10 41.8 7.0 2.4e-10 40.8 7.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK75710.1 - 6.1e-08 33.3 0.0 2.7e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 ABK75710.1 - 0.00013 21.7 0.2 0.00056 19.7 0.2 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal TetR_N PF00440.23 ABK75711.1 - 1.3e-10 40.8 0.2 3.6e-10 39.5 0.2 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_22 PF17928.1 ABK75711.1 - 0.045 14.1 0.8 0.094 13.1 0.1 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF3000 PF11452.8 ABK75712.1 - 6.4e-75 250.5 0.3 7.4e-75 250.3 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3000) Glyoxalase_6 PF18029.1 ABK75712.1 - 0.09 13.6 0.7 0.36 11.6 0.7 2.1 1 1 0 1 1 1 0 Glyoxalase-like domain Phage_TAC_2 PF06894.11 ABK75712.1 - 0.23 11.3 0.1 0.35 10.7 0.1 1.2 1 0 0 1 1 1 0 Bacteriophage lambda tail assembly chaperone, TAC, protein G Cutinase PF01083.22 ABK75713.1 - 1.2e-47 162.2 0.0 1.4e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 Cutinase Lipase_3 PF01764.25 ABK75713.1 - 0.00075 19.4 0.0 0.0012 18.7 0.0 1.4 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.7 ABK75713.1 - 0.054 13.3 0.1 0.083 12.7 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2749 PF10907.8 ABK75713.1 - 2.3 8.4 4.4 0.58 10.4 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) zf-UBP PF02148.19 ABK75714.1 - 5.5e-11 42.6 11.7 7.8e-11 42.2 11.7 1.2 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein DUF3159 PF11361.8 ABK75715.1 - 3.1e-72 242.3 18.2 3.6e-72 242.1 18.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3159) IspA PF04279.15 ABK75715.1 - 2.1 8.5 8.3 6.1 7.0 8.3 1.8 1 1 0 1 1 1 0 Intracellular septation protein A DUF2070 PF09843.9 ABK75715.1 - 5.2 5.2 8.8 0.72 8.1 5.1 1.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Pox_A14 PF05767.12 ABK75716.1 - 7 6.9 7.6 9.3 6.5 0.0 4.1 5 0 0 5 5 5 0 Poxvirus virion envelope protein A14 SecG PF03840.14 ABK75717.1 - 7.4e-15 54.8 8.9 8.9e-15 54.5 8.9 1.0 1 0 0 1 1 1 1 Preprotein translocase SecG subunit Acyl-CoA_dh_1 PF00441.24 ABK75718.1 - 2.1e-27 96.2 0.0 2.9e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK75718.1 - 2.5e-25 89.3 0.0 4.7e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ABK75718.1 - 3e-25 88.2 0.0 5.6e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ABK75718.1 - 9.9e-05 22.6 0.0 0.00017 21.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ABC_tran PF00005.27 ABK75719.1 - 3.6e-23 82.6 0.0 5.1e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK75719.1 - 3.5e-11 43.5 0.1 4.7e-08 33.2 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK75719.1 - 0.0012 18.3 0.0 0.4 10.1 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 ABK75719.1 - 0.0016 18.2 0.4 0.0066 16.2 0.1 2.0 1 1 1 2 2 2 1 AAA domain SbcCD_C PF13558.6 ABK75719.1 - 0.0024 18.1 0.1 0.13 12.5 0.1 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_27 PF13514.6 ABK75719.1 - 0.0091 15.6 0.0 0.024 14.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain GcnA_N PF18229.1 ABK75719.1 - 0.022 14.8 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 N-acetyl-beta-D-glucosaminidase N-terminal domain ATP_bind_1 PF03029.17 ABK75719.1 - 0.031 14.1 0.0 0.047 13.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.17 ABK75719.1 - 0.039 13.7 0.0 3.7 7.2 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 ABK75719.1 - 0.046 13.4 0.1 1.3 8.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 ABK75719.1 - 0.076 12.8 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRP54 PF00448.22 ABK75719.1 - 0.076 12.6 0.0 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 ABK75719.1 - 0.085 13.3 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 ABK75719.1 - 0.086 11.8 0.1 0.17 10.9 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 ABK75719.1 - 0.11 12.7 0.0 0.34 11.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.7 ABK75719.1 - 0.16 10.9 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain EamA PF00892.20 ABK75720.1 - 9.7e-24 84.1 28.0 9.2e-12 45.3 13.1 2.0 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 ABK75720.1 - 0.087 12.0 2.5 0.061 12.5 0.8 1.6 1 1 0 1 1 1 0 Nucleotide-sugar transporter TPT PF03151.16 ABK75720.1 - 0.1 12.0 5.5 0.11 11.9 3.2 2.2 1 1 0 2 2 2 0 Triose-phosphate Transporter family Sigma70_r2 PF04542.14 ABK75721.1 - 7e-16 57.8 0.5 1.4e-15 56.8 0.5 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 ABK75721.1 - 1e-12 47.4 0.0 1.7e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 ABK75721.1 - 4.3e-12 45.5 0.1 7.7e-12 44.7 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 ABK75721.1 - 0.00019 21.4 0.1 0.00039 20.4 0.1 1.5 1 1 0 1 1 1 1 ECF sigma factor GerE PF00196.19 ABK75721.1 - 0.007 15.9 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_23 PF13384.6 ABK75721.1 - 0.033 14.0 0.1 0.096 12.5 0.1 1.9 1 1 0 1 1 1 0 Homeodomain-like domain Terminase_5 PF06056.12 ABK75721.1 - 0.13 12.2 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) RibD_C PF01872.17 ABK75722.1 - 1.9e-49 168.2 0.2 2.9e-49 167.6 0.2 1.3 1 0 0 1 1 1 1 RibD C-terminal domain dCMP_cyt_deam_1 PF00383.23 ABK75722.1 - 5e-17 61.6 0.0 8.5e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ABK75722.1 - 9.4e-07 28.7 0.0 1.6e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase Ldh_2 PF02615.14 ABK75722.1 - 0.0082 15.3 2.1 0.016 14.4 2.1 1.6 1 1 0 1 1 1 1 Malate/L-lactate dehydrogenase PTA_PTB PF01515.19 ABK75723.1 - 1.3e-130 435.4 0.4 1.8e-130 434.9 0.4 1.2 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase DRTGG PF07085.12 ABK75723.1 - 5.9e-27 93.5 0.7 5e-26 90.5 0.1 2.8 3 0 0 3 3 3 1 DRTGG domain AAA_26 PF13500.6 ABK75723.1 - 8.2e-22 78.0 0.1 3.8e-21 75.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 ABK75723.1 - 0.044 13.8 0.0 0.14 12.2 0.0 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RFX5_N PF18326.1 ABK75723.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 RFX5 N-terminal domain BcrAD_BadFG PF01869.20 ABK75724.1 - 4.5e-24 85.4 0.2 5.2e-24 85.2 0.2 1.0 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family Queuosine_synth PF02547.15 ABK75724.1 - 0.067 12.3 0.1 0.098 11.8 0.1 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein Pkinase PF00069.25 ABK75725.1 - 1.7e-42 145.6 0.0 2.1e-42 145.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ABK75725.1 - 6.3e-26 91.2 0.0 8.5e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ABK75725.1 - 0.00011 21.2 0.0 0.00017 20.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ABK75725.1 - 0.0024 17.8 10.9 0.064 13.2 0.1 3.1 1 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 ABK75725.1 - 0.0089 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3357 PF11837.8 ABK75725.1 - 1.6 9.2 4.5 0.42 11.1 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) YceI PF04264.13 ABK75727.1 - 5.3e-29 101.7 0.0 6.1e-29 101.5 0.0 1.0 1 0 0 1 1 1 1 YceI-like domain PRiA4_ORF3 PF07929.11 ABK75730.1 - 2.1e-51 174.1 0.0 2.5e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein FCD PF07729.12 ABK75732.1 - 8.8e-26 90.8 5.6 1.9e-25 89.7 5.6 1.6 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 ABK75732.1 - 2.8e-12 46.1 0.5 6.7e-12 44.9 0.5 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family DprA_WH PF17782.1 ABK75732.1 - 0.00084 19.4 3.5 0.00093 19.3 1.1 2.2 2 0 0 2 2 2 1 DprA winged helix domain HTH_DeoR PF08220.12 ABK75732.1 - 0.00096 18.9 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 ABK75732.1 - 0.0038 17.1 0.0 0.0076 16.2 0.0 1.5 1 0 0 1 1 1 1 HTH domain TrmB PF01978.19 ABK75732.1 - 0.062 13.2 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_15 PF12324.8 ABK75732.1 - 0.085 12.8 0.6 0.51 10.3 0.2 2.3 2 1 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase Rrf2 PF02082.20 ABK75732.1 - 0.089 13.1 0.0 0.19 12.1 0.0 1.6 1 1 0 1 1 1 0 Transcriptional regulator DciA PF05258.12 ABK75732.1 - 0.1 13.0 0.2 0.25 11.8 0.2 1.8 1 0 0 1 1 1 0 Dna[CI] antecedent, DciA FluMu_N PF17891.1 ABK75732.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Mu-like prophage FluMu N-terminal domain Fe_dep_repress PF01325.19 ABK75732.1 - 0.14 12.4 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain NUDIX PF00293.28 ABK75733.1 - 3.4e-11 43.3 0.2 4.3e-11 43.0 0.2 1.2 1 0 0 1 1 1 1 NUDIX domain Alpha-E PF04168.12 ABK75734.1 - 8.1e-76 255.6 6.2 9.1e-76 255.4 6.2 1.0 1 0 0 1 1 1 1 A predicted alpha-helical domain with a conserved ER motif. GMC_oxred_N PF00732.19 ABK75735.1 - 9.6e-73 245.1 0.0 1.3e-72 244.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ABK75735.1 - 3.5e-36 124.9 0.3 6.8e-36 123.9 0.3 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 ABK75735.1 - 0.0045 16.3 0.0 0.0091 15.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 ABK75735.1 - 0.012 15.8 0.1 0.039 14.2 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain MazG PF03819.17 ABK75736.1 - 1e-23 83.3 0.0 1.9e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain PRA-PH PF01503.17 ABK75736.1 - 0.012 16.1 2.1 0.038 14.4 0.1 2.5 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase Trp_oprn_chp PF09534.10 ABK75737.1 - 0.0035 17.1 1.1 0.0056 16.5 1.1 1.4 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Yip1 PF04893.17 ABK75737.1 - 0.033 13.9 2.0 0.046 13.4 2.0 1.1 1 0 0 1 1 1 0 Yip1 domain MWFE PF15879.5 ABK75737.1 - 0.064 13.4 2.3 0.18 12.0 0.1 2.3 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit LapA_dom PF06305.11 ABK75737.1 - 0.097 12.5 5.0 0.3 10.9 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Pilin_N PF07790.11 ABK75737.1 - 1.6 9.7 5.2 4.8 8.2 0.3 2.3 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal Phage_holin_3_6 PF07332.11 ABK75737.1 - 7.5 6.6 10.1 16 5.6 10.1 1.6 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF1731 PF08338.11 ABK75738.1 - 5.3e-17 61.4 1.1 1.1e-15 57.2 0.2 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1731) Epimerase PF01370.21 ABK75738.1 - 3.4e-14 52.9 0.0 6.6e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polyketide_cyc2 PF10604.9 ABK75738.1 - 0.00023 21.4 2.2 0.00075 19.8 2.2 1.8 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport GDP_Man_Dehyd PF16363.5 ABK75738.1 - 0.00078 18.9 0.1 0.41 10.0 0.0 2.6 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 ABK75738.1 - 0.058 12.5 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Polyketide_cyc PF03364.20 ABK75738.1 - 0.098 12.9 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Glyoxalase PF00903.25 ABK75738.1 - 0.14 12.3 0.0 1.8 8.8 0.0 2.3 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily AA_permease_2 PF13520.6 ABK75740.1 - 9.9e-36 123.5 54.2 1.2e-35 123.2 54.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ABK75740.1 - 6.8e-24 84.3 40.4 1.2e-23 83.5 40.4 1.4 1 0 0 1 1 1 1 Amino acid permease MMPL PF03176.15 ABK75741.1 - 1e-177 590.1 28.8 3e-92 309.1 11.7 2.5 2 0 0 2 2 2 2 MMPL family Sterol-sensing PF12349.8 ABK75741.1 - 0.00046 20.0 2.7 0.00046 20.0 2.7 2.4 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Baculo_PEP_C PF04513.12 ABK75741.1 - 0.0027 17.7 2.5 1.4 9.0 0.1 2.8 2 1 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus MFS_1 PF07690.16 ABK75742.1 - 1.3e-41 142.7 54.6 6e-35 120.8 30.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ABK75742.1 - 0.00095 18.6 35.7 0.023 14.0 15.5 2.1 1 1 1 2 2 2 2 Uncharacterised MFS-type transporter YbfB PspC PF04024.12 ABK75742.1 - 0.19 11.6 0.2 0.19 11.6 0.2 3.9 4 1 0 4 4 4 0 PspC domain DUF4878 PF12870.7 ABK75743.1 - 0.00027 21.2 0.0 0.0004 20.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4878) DUF2561 PF10812.8 ABK75743.1 - 0.019 15.0 1.7 0.019 15.0 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) WAC_Acf1_DNA_bd PF10537.9 ABK75743.1 - 0.13 12.8 0.0 0.2 12.2 0.0 1.2 1 0 0 1 1 1 0 ATP-utilising chromatin assembly and remodelling N-terminal G_glu_transpept PF01019.21 ABK75744.1 - 4.2e-150 500.9 0.0 4.8e-150 500.7 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase AbiEi_4 PF13338.6 ABK75745.1 - 4.1e-09 36.5 1.3 9e-09 35.4 0.4 2.2 2 0 0 2 2 2 1 Transcriptional regulator, AbiEi antitoxin DUF559 PF04480.12 ABK75745.1 - 4.5e-09 36.1 0.1 8.4e-09 35.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF559) MTES_1575 PF18741.1 ABK75745.1 - 4.6e-09 36.3 0.3 1e-08 35.2 0.1 1.8 2 0 0 2 2 2 1 REase_MTES_1575 AbiEi_3_N PF17194.4 ABK75745.1 - 0.02 14.9 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain AbiEi_1 PF09407.10 ABK75745.1 - 0.049 13.9 0.2 0.12 12.7 0.1 1.7 2 0 0 2 2 2 0 AbiEi antitoxin C-terminal domain HTH_AsnC-type PF13404.6 ABK75745.1 - 1 9.2 4.8 0.3 10.9 0.9 2.2 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Beta-lactamase2 PF13354.6 ABK75746.1 - 3.3e-42 144.4 0.0 4e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase enzyme family Beta-lactamase PF00144.24 ABK75746.1 - 1.6e-27 96.6 0.1 1.1e-26 93.9 0.1 1.9 1 1 0 1 1 1 1 Beta-lactamase Transpeptidase PF00905.22 ABK75746.1 - 0.0097 15.1 0.0 0.15 11.2 0.0 2.0 2 0 0 2 2 2 1 Penicillin binding protein transpeptidase domain Peptidase_S13 PF02113.15 ABK75746.1 - 0.018 13.8 0.0 4.4 5.9 0.0 2.2 2 0 0 2 2 2 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family TAT_signal PF10518.9 ABK75746.1 - 0.034 14.0 1.2 0.034 14.0 1.2 2.0 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence Glutaminase PF04960.15 ABK75746.1 - 0.1 11.8 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Glutaminase CinA_KH PF18146.1 ABK75746.1 - 0.12 12.5 0.1 1.8 8.7 0.0 2.4 2 0 0 2 2 2 0 Damage-inducible protein CinA KH domain CHASE8 PF17152.4 ABK75746.1 - 0.12 12.6 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Periplasmic sensor domain rve PF00665.26 ABK75747.1 - 1.8e-23 83.0 0.1 4.5e-23 81.7 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 ABK75747.1 - 8.9e-14 51.4 2.0 2.3e-13 50.1 1.4 2.0 2 0 0 2 2 2 1 HTH-like domain rve_3 PF13683.6 ABK75747.1 - 5.8e-12 45.2 0.0 1.3e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 ABK75747.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain MlaE PF02405.16 ABK75748.1 - 1.4e-52 178.4 28.9 1.8e-52 178.1 28.9 1.1 1 0 0 1 1 1 1 Permease MlaE Glyco_hydro_77 PF02446.17 ABK75749.1 - 3.2e-123 412.1 0.0 4.1e-123 411.7 0.0 1.0 1 0 0 1 1 1 1 4-alpha-glucanotransferase CoA_transf_3 PF02515.17 ABK75750.1 - 4.7e-111 371.5 0.6 5.3e-111 371.3 0.6 1.0 1 0 0 1 1 1 1 CoA-transferase family III Sod_Cu PF00080.20 ABK75751.1 - 2.4e-28 99.1 2.4 3.3e-28 98.6 2.4 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) MFS_1 PF07690.16 ABK75752.1 - 1.6e-48 165.5 51.7 1.7e-29 102.8 29.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ABK75752.1 - 0.00042 19.0 10.3 0.00042 19.0 10.3 2.9 2 2 1 3 3 3 1 MFS/sugar transport protein Sugar_tr PF00083.24 ABK75752.1 - 0.0062 15.5 27.8 0.0077 15.1 5.9 3.2 2 1 1 3 3 3 3 Sugar (and other) transporter OATP PF03137.20 ABK75752.1 - 0.34 9.1 6.1 2.6 6.2 6.0 2.3 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 ABK75754.1 - 4.8e-37 127.7 54.6 7.2e-25 87.6 27.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK75754.1 - 4.8e-26 91.6 28.5 7.6e-18 64.6 11.6 2.5 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 ABK75754.1 - 1.1e-06 28.3 24.0 3.7e-05 23.2 7.9 2.3 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 ABK75754.1 - 9.6 4.9 12.6 0.56 9.0 1.9 2.8 3 0 0 3 3 3 0 MFS_1 like family Pyr_redox_2 PF07992.14 ABK75755.1 - 9.1e-63 212.2 1.0 1.1e-62 211.9 1.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ABK75755.1 - 2.3e-20 72.9 0.3 2.4e-15 56.9 0.5 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 ABK75755.1 - 4.8e-14 52.7 0.0 5.2e-13 49.4 0.0 2.6 3 0 0 3 3 2 1 Reductase C-terminal HI0933_like PF03486.14 ABK75755.1 - 1.5e-11 43.7 2.7 0.0025 16.6 0.0 4.0 4 0 0 4 4 4 4 HI0933-like protein Pyr_redox_3 PF13738.6 ABK75755.1 - 9.2e-09 35.0 0.0 9.7e-07 28.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ABK75755.1 - 1.2e-08 35.0 12.0 0.044 13.4 2.8 4.1 3 1 1 4 4 4 3 FAD dependent oxidoreductase Amino_oxidase PF01593.24 ABK75755.1 - 8.1e-08 32.0 0.2 1.3e-05 24.7 0.1 2.4 2 1 0 3 3 3 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ABK75755.1 - 5.1e-07 29.8 5.0 0.017 15.3 0.1 3.3 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 ABK75755.1 - 6.1e-07 28.8 3.0 0.19 10.8 0.0 3.1 3 0 0 3 3 3 3 Lycopene cyclase protein FAD_binding_2 PF00890.24 ABK75755.1 - 2.6e-06 26.8 15.6 0.015 14.4 0.9 4.1 3 1 1 4 4 4 3 FAD binding domain GIDA PF01134.22 ABK75755.1 - 3.1e-06 26.5 5.9 0.68 8.9 0.0 3.6 3 1 1 4 4 4 3 Glucose inhibited division protein A NAD_binding_9 PF13454.6 ABK75755.1 - 8.3e-06 25.9 5.8 0.063 13.3 0.4 4.1 3 1 1 4 4 4 1 FAD-NAD(P)-binding 3HCDH_N PF02737.18 ABK75755.1 - 0.00062 19.7 0.1 0.0049 16.8 0.3 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 ABK75755.1 - 0.0043 16.4 0.0 0.057 12.8 0.1 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ABK75755.1 - 0.0073 15.6 6.0 0.4 10.0 1.6 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 ABK75755.1 - 0.02 15.1 0.5 5 7.4 0.1 3.0 3 0 0 3 3 3 0 TrkA-N domain Trp_halogenase PF04820.14 ABK75755.1 - 0.031 13.1 5.5 5.5 5.7 0.0 3.1 2 1 1 3 3 3 0 Tryptophan halogenase FAD_binding_3 PF01494.19 ABK75755.1 - 0.049 12.9 2.6 1.5 8.0 0.6 2.2 2 0 0 2 2 2 0 FAD binding domain FLgD_tudor PF13861.6 ABK75755.1 - 0.061 13.6 0.0 0.2 11.9 0.0 2.0 1 1 0 1 1 1 0 FlgD Tudor-like domain GMC_oxred_N PF00732.19 ABK75755.1 - 0.14 11.5 0.0 1.8 7.9 0.1 2.1 2 0 0 2 2 2 0 GMC oxidoreductase UDPG_MGDP_dh_N PF03721.14 ABK75755.1 - 0.14 11.7 0.1 0.28 10.7 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 ABK75755.1 - 0.19 12.2 0.5 8.8 6.8 0.4 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_oxidored PF12831.7 ABK75755.1 - 9.9 5.4 11.6 4.9 6.4 0.1 3.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase FUSC_2 PF13515.6 ABK75756.1 - 9.2e-14 51.7 16.2 9.2e-14 51.7 16.2 3.5 2 2 1 3 3 3 1 Fusaric acid resistance protein-like Polysacc_deac_1 PF01522.21 ABK75757.1 - 3.1e-20 72.3 0.0 5.3e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 ABK75757.1 - 2e-08 34.1 0.1 2.7e-08 33.7 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 ABK75757.1 - 0.14 10.4 0.0 0.19 10.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) TetR_N PF00440.23 ABK75758.1 - 6.9e-10 38.6 0.7 1.3e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 ABK75758.1 - 0.00021 21.5 0.1 0.00056 20.2 0.0 1.7 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_33 PF13305.6 ABK75758.1 - 0.006 17.3 0.8 0.006 17.3 0.8 2.3 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain F420H2_quin_red PF04075.14 ABK75759.1 - 1.6e-19 70.3 0.3 1.8e-19 70.2 0.3 1.0 1 0 0 1 1 1 1 F420H(2)-dependent quinone reductase DAO PF01266.24 ABK75759.1 - 0.0044 16.6 0.0 0.005 16.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF2255 PF10012.9 ABK75759.1 - 0.056 13.6 0.1 0.062 13.5 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) PRiA4_ORF3 PF07929.11 ABK75760.1 - 2.1e-51 174.1 0.0 2.5e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein Nitroreductase PF00881.24 ABK75762.1 - 1e-28 100.5 0.1 1.4e-28 100.1 0.1 1.2 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 ABK75762.1 - 1.4e-08 34.5 0.0 0.0052 16.4 0.0 3.1 2 1 1 3 3 3 3 Putative TM nitroreductase DUF2236 PF09995.9 ABK75762.1 - 0.0083 16.3 2.1 0.012 15.8 1.9 1.4 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) CPBP PF02517.16 ABK75764.1 - 1.4e-09 38.2 17.7 4.4e-09 36.6 15.2 2.9 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease DUF2754 PF10953.8 ABK75764.1 - 0.12 12.7 6.8 3.7 7.9 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2754) DUF948 PF06103.11 ABK75765.1 - 0.14 12.4 0.3 0.14 12.4 0.3 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Phage_holin_3_6 PF07332.11 ABK75765.1 - 0.16 12.0 5.9 0.34 11.0 5.9 1.5 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Cupin_2 PF07883.11 ABK75767.1 - 6.3e-06 25.8 2.2 1e-05 25.1 1.3 1.7 1 1 1 2 2 2 1 Cupin domain Cupin_7 PF12973.7 ABK75767.1 - 0.04 13.8 0.0 0.07 13.0 0.0 1.4 1 1 0 1 1 1 0 ChrR Cupin-like domain BPD_transp_1 PF00528.22 ABK75768.1 - 1.5e-25 90.0 11.5 1.5e-25 90.0 11.5 1.9 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 ABK75768.1 - 7.7e-10 38.6 0.4 7.7e-10 38.6 0.4 3.8 4 1 0 4 4 4 1 N-terminal TM domain of oligopeptide transport permease C DUF805 PF05656.14 ABK75768.1 - 0.56 10.6 13.6 0.12 12.8 7.4 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF805) GntR PF00392.21 ABK75769.1 - 1.5e-16 59.8 2.9 1.6e-16 59.7 1.1 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family FCD PF07729.12 ABK75769.1 - 3e-14 53.5 2.9 6.1e-14 52.5 2.9 1.5 1 0 0 1 1 1 1 FCD domain Fe_dep_repress PF01325.19 ABK75769.1 - 3.2e-05 24.0 0.0 0.00025 21.2 0.0 2.1 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain HTH_Crp_2 PF13545.6 ABK75769.1 - 0.00037 20.4 0.6 0.0012 18.7 0.5 2.0 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain MarR PF01047.22 ABK75769.1 - 0.00082 19.3 0.4 0.0018 18.1 0.0 1.7 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.7 ABK75769.1 - 0.0017 18.2 0.4 0.0017 18.2 0.4 2.5 3 0 0 3 3 3 1 MarR family PaaX PF07848.12 ABK75769.1 - 0.01 16.0 1.3 0.059 13.6 0.1 2.4 2 0 0 2 2 2 0 PaaX-like protein TrmB PF01978.19 ABK75769.1 - 0.014 15.2 0.0 0.034 14.0 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 ABK75769.1 - 0.023 14.5 0.2 0.065 13.0 0.2 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_11 PF08279.12 ABK75769.1 - 0.1 12.5 0.1 0.36 10.8 0.1 1.9 1 0 0 1 1 1 0 HTH domain HTH_24 PF13412.6 ABK75769.1 - 0.11 12.0 0.2 0.28 10.8 0.2 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Glyco_hydro_6 PF01341.17 ABK75770.1 - 3.3e-67 227.4 0.0 4.1e-67 227.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 AIRS_C PF02769.22 ABK75771.1 - 4.3e-56 189.4 3.4 3e-34 118.4 0.4 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.24 ABK75771.1 - 7.2e-49 164.4 5.7 1.3e-23 83.5 0.5 2.6 2 0 0 2 2 2 2 AIR synthase related protein, N-terminal domain FGAR-AT_linker PF18072.1 ABK75771.1 - 1e-17 64.4 0.0 2e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain H2TH PF06831.14 ABK75773.1 - 4.6e-25 87.4 0.0 6.7e-25 86.9 0.0 1.2 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain zf-FPG_IleRS PF06827.14 ABK75773.1 - 9.1e-09 35.0 3.2 1.8e-08 34.1 3.2 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS Fapy_DNA_glyco PF01149.24 ABK75773.1 - 8.9e-05 23.1 0.0 0.0002 21.9 0.0 1.6 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase N-terminal domain HSP70 PF00012.20 ABK75774.1 - 9.4e-16 57.1 0.1 1.3e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ABK75774.1 - 7.7e-05 21.7 0.0 0.00012 21.0 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.16 ABK75774.1 - 0.00014 21.7 1.1 0.00037 20.3 1.1 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 ABK75774.1 - 0.14 11.6 0.1 0.24 10.9 0.1 1.4 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Fer4_15 PF13459.6 ABK75775.1 - 1.1e-12 48.5 0.2 1.3e-12 48.3 0.2 1.1 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_13 PF13370.6 ABK75775.1 - 5.9e-11 42.7 0.1 6.7e-11 42.6 0.1 1.0 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_19 PF06902.11 ABK75775.1 - 5.7e-07 29.5 0.0 6.8e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Divergent 4Fe-4S mono-cluster tRNA_Me_trans PF03054.16 ABK75776.1 - 9.6e-113 376.6 0.0 1.1e-112 376.4 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 ABK75776.1 - 0.001 18.7 0.1 0.0014 18.2 0.1 1.2 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.21 ABK75776.1 - 0.0068 16.1 0.0 0.0091 15.7 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.17 ABK75776.1 - 0.031 13.4 0.0 0.053 12.6 0.0 1.4 1 1 0 1 1 1 0 NAD synthase DUF2019 PF09450.10 ABK75776.1 - 0.18 11.7 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) QueC PF06508.13 ABK75776.1 - 0.2 11.1 0.3 0.37 10.3 0.3 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Pribosyltran PF00156.27 ABK75777.1 - 2.4e-08 33.6 0.2 4.1e-08 32.9 0.1 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain TetR_C_24 PF17932.1 ABK75778.1 - 2.4e-20 72.9 0.0 5.1e-20 71.8 0.0 1.5 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK75778.1 - 2.5e-17 62.4 0.1 4.1e-17 61.7 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_29 PF17938.1 ABK75778.1 - 0.00012 22.1 0.0 0.00021 21.3 0.0 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_11 PF16859.5 ABK75778.1 - 0.0006 20.1 0.0 0.0056 17.0 0.0 2.2 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_17 PF17922.1 ABK75778.1 - 0.0013 18.8 0.0 0.0036 17.4 0.0 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_4 PF08359.11 ABK75778.1 - 0.0024 18.0 0.0 0.0041 17.3 0.0 1.4 1 0 0 1 1 1 1 YsiA-like protein, C-terminal region MFS_1 PF07690.16 ABK75779.1 - 1.5e-42 145.8 47.2 1.5e-42 145.8 47.2 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF4226 PF10774.9 ABK75780.1 - 0.016 15.5 0.7 0.036 14.3 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4226) CdvA PF18822.1 ABK75780.1 - 0.027 14.3 0.5 0.043 13.6 0.5 1.2 1 0 0 1 1 1 0 CdvA-like coiled-coil domain HTH_30 PF13556.6 ABK75781.1 - 3.6e-17 61.9 0.4 8.6e-17 60.7 0.4 1.7 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_8 PF02954.19 ABK75781.1 - 0.0016 18.2 0.4 0.0036 17.1 0.4 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family HTH_AsnC-type PF13404.6 ABK75781.1 - 0.021 14.7 2.1 0.058 13.2 0.2 2.9 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain Sigma70_r4_2 PF08281.12 ABK75781.1 - 0.053 13.2 0.0 0.15 11.7 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 Vut_1 PF02592.15 ABK75782.1 - 5.2e-45 153.4 7.4 5.2e-45 153.4 7.4 1.4 2 0 0 2 2 2 1 Putative vitamin uptake transporter Amidohydro_1 PF01979.20 ABK75784.1 - 4.1e-23 82.3 0.1 1.4e-22 80.5 0.1 1.7 1 1 0 1 1 1 1 Amidohydrolase family DHOase PF12890.7 ABK75784.1 - 2.3e-13 50.3 0.0 5e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Dihydro-orotase-like Amidohydro_3 PF07969.11 ABK75784.1 - 6e-12 45.8 8.4 9.4e-07 28.6 0.2 2.4 1 1 0 2 2 2 2 Amidohydrolase family TauD PF02668.16 ABK75785.1 - 9.2e-55 186.3 0.2 1e-54 186.1 0.2 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CMD PF02627.20 ABK75786.1 - 1.7e-13 50.4 0.0 3.1e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Inositol_P PF00459.25 ABK75787.1 - 1.4e-50 172.4 0.2 1.7e-50 172.0 0.2 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF2236 PF09995.9 ABK75788.1 - 5.6e-52 177.2 0.3 8.4e-52 176.6 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) PqqA PF08042.11 ABK75789.1 - 3e-08 33.4 0.4 3.8e-08 33.1 0.4 1.2 1 0 0 1 1 1 1 PqqA family ABC_tran PF00005.27 ABK75790.1 - 7.2e-46 156.1 0.0 2.4e-21 76.7 0.0 3.3 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 ABK75790.1 - 2.8e-13 50.4 12.1 0.0013 18.7 0.1 4.6 4 1 1 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ABK75790.1 - 8.1e-10 38.5 0.1 0.054 12.9 0.0 4.3 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ABK75790.1 - 1.1e-08 35.4 0.0 3.6e-05 24.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 ABK75790.1 - 3.8e-08 33.0 0.2 0.0058 16.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 ABK75790.1 - 2.8e-07 31.2 3.9 0.0068 16.9 0.0 3.2 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 ABK75790.1 - 2.1e-06 27.8 0.2 0.11 12.6 0.0 2.9 3 0 0 3 3 2 2 50S ribosome-binding GTPase MeaB PF03308.16 ABK75790.1 - 2.1e-06 26.9 1.8 0.035 13.1 0.1 2.6 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 ABK75790.1 - 5.3e-06 26.9 6.5 0.013 15.9 0.1 3.1 3 1 0 3 3 3 2 AAA ATPase domain AAA_30 PF13604.6 ABK75790.1 - 7.9e-06 25.7 4.9 0.018 14.8 0.3 3.1 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 ABK75790.1 - 1.1e-05 25.4 0.1 0.15 11.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 ABK75790.1 - 2.3e-05 25.0 0.3 0.14 12.7 0.1 2.8 2 0 0 2 2 2 2 AAA domain cobW PF02492.19 ABK75790.1 - 5.7e-05 22.8 0.1 0.065 12.8 0.0 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 ABK75790.1 - 8.1e-05 22.9 4.0 0.12 12.6 0.0 3.1 3 0 0 3 3 2 2 AAA domain ABC_tran_Xtn PF12848.7 ABK75790.1 - 0.00052 20.0 13.9 0.01 15.9 13.9 2.3 1 1 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.12 ABK75790.1 - 0.00091 18.6 2.0 0.069 12.4 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin NACHT PF05729.12 ABK75790.1 - 0.0016 18.3 0.7 1.6 8.6 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_27 PF13514.6 ABK75790.1 - 0.0017 18.0 2.7 0.5 9.9 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.6 ABK75790.1 - 0.0023 18.1 5.3 0.51 10.5 0.0 3.5 3 1 0 3 3 2 2 AAA domain AAA_25 PF13481.6 ABK75790.1 - 0.0023 17.5 2.8 3.2 7.3 0.0 3.9 4 0 0 4 4 4 1 AAA domain Dynamin_N PF00350.23 ABK75790.1 - 0.0026 17.8 0.6 3 7.9 0.0 2.8 3 0 0 3 3 3 1 Dynamin family AAA_24 PF13479.6 ABK75790.1 - 0.0063 16.3 0.1 1.5 8.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain GTP_EFTU PF00009.27 ABK75790.1 - 0.008 15.7 0.0 1.4 8.4 0.0 2.8 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 ABK75790.1 - 0.0088 16.1 0.0 5.7 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 ABK75790.1 - 0.009 15.9 0.1 0.8 9.6 0.0 3.0 3 0 0 3 3 3 1 NTPase AAA_15 PF13175.6 ABK75790.1 - 0.01 15.6 0.1 2 8.0 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Ploopntkinase3 PF18751.1 ABK75790.1 - 0.011 15.7 0.8 0.14 12.0 0.0 2.7 2 1 0 2 2 2 0 P-loop Nucleotide Kinase3 PRK PF00485.18 ABK75790.1 - 0.011 15.5 0.2 5.4 6.7 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Adeno_IVa2 PF02456.15 ABK75790.1 - 0.014 14.2 0.1 1.4 7.7 0.1 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein KAP_NTPase PF07693.14 ABK75790.1 - 0.02 14.2 0.0 2.1 7.5 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain NB-ARC PF00931.22 ABK75790.1 - 0.03 13.5 0.2 2.3 7.4 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain TIR-like PF10137.9 ABK75790.1 - 0.03 14.3 0.0 0.63 10.0 0.0 2.3 2 0 0 2 2 2 0 Predicted nucleotide-binding protein containing TIR-like domain PhetRS_B1 PF18262.1 ABK75790.1 - 0.037 14.3 0.0 0.091 13.0 0.0 1.7 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain RNA_helicase PF00910.22 ABK75790.1 - 0.037 14.4 0.0 13 6.2 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.14 ABK75790.1 - 0.047 13.7 4.1 9.7 6.2 0.1 4.0 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) CLP1_P PF16575.5 ABK75790.1 - 0.048 13.5 0.0 12 5.7 0.0 2.9 3 0 0 3 3 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop MutS_V PF00488.21 ABK75790.1 - 0.055 13.5 0.4 1.8 8.6 0.0 2.3 2 0 0 2 2 2 0 MutS domain V T2SSE PF00437.20 ABK75790.1 - 0.063 12.3 0.2 4.1 6.4 0.0 2.6 3 0 0 3 3 3 0 Type II/IV secretion system protein Roc PF08477.13 ABK75790.1 - 0.075 13.2 0.0 6.2 7.1 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 ABK75790.1 - 0.081 12.9 0.2 13 5.8 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 ABK75790.1 - 0.11 12.9 0.2 31 5.0 0.0 2.9 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) dNK PF01712.19 ABK75790.1 - 0.12 12.2 0.2 16 5.2 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase Ploopntkinase1 PF18748.1 ABK75790.1 - 0.14 11.6 0.0 2 7.9 0.0 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 Peptidase_M23 PF01551.22 ABK75790.1 - 0.15 12.3 0.4 33 4.8 0.0 3.1 2 1 0 2 2 2 0 Peptidase family M23 AAA_13 PF13166.6 ABK75790.1 - 0.18 10.4 3.9 7.6 5.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.15 ABK75790.1 - 0.18 11.7 0.0 10 6.0 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain ATP-synt_ab PF00006.25 ABK75790.1 - 0.21 11.2 0.5 13 5.4 0.3 2.3 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SRP54 PF00448.22 ABK75790.1 - 0.22 11.1 0.6 5 6.7 0.0 2.9 2 1 0 3 3 3 0 SRP54-type protein, GTPase domain ABC_ATPase PF09818.9 ABK75790.1 - 0.42 9.3 4.3 6.5 5.4 0.1 3.0 3 0 0 3 3 3 0 Predicted ATPase of the ABC class DUF3584 PF12128.8 ABK75790.1 - 0.6 7.6 12.8 0.33 8.4 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) DUF87 PF01935.17 ABK75790.1 - 0.71 9.9 6.1 4.7 7.2 0.1 2.9 2 1 1 3 3 3 0 Helicase HerA, central domain Cytidylate_kin PF02224.18 ABK75790.1 - 5.2 6.7 8.3 7.9 6.1 0.0 3.4 3 1 0 3 3 3 0 Cytidylate kinase MgtE PF01769.16 ABK75791.1 - 5.8e-24 84.9 10.1 9.5e-24 84.2 10.1 1.4 1 0 0 1 1 1 1 Divalent cation transporter MgtE_N PF03448.17 ABK75791.1 - 8.4e-19 68.1 2.1 1.9e-18 66.9 2.1 1.7 1 0 0 1 1 1 1 MgtE intracellular N domain CBS PF00571.28 ABK75791.1 - 3.6e-14 52.9 5.0 5.7e-09 36.3 0.9 2.7 3 0 0 3 3 3 2 CBS domain FliG_M PF14841.6 ABK75791.1 - 0.016 15.4 1.0 0.096 12.9 0.4 2.5 2 1 1 3 3 3 0 FliG middle domain DUF2628 PF10947.8 ABK75791.1 - 3.2 8.2 7.5 0.44 10.9 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) DPM3 PF08285.11 ABK75791.1 - 6.5 7.0 7.1 6.6 7.0 2.6 3.0 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) NUDIX PF00293.28 ABK75792.1 - 6.6e-06 26.2 1.0 0.0077 16.3 0.2 2.8 2 1 0 2 2 2 2 NUDIX domain TetR_C_11 PF16859.5 ABK75793.1 - 4.8e-32 110.6 4.7 4.8e-32 110.6 4.7 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK75793.1 - 4.5e-13 48.8 0.9 2.1e-12 46.7 0.5 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_7 PF14246.6 ABK75793.1 - 0.016 15.3 0.0 0.035 14.1 0.0 1.6 1 0 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal domain DnaG_DnaB_bind PF08278.11 ABK75793.1 - 0.1 13.2 0.0 1.1 9.8 0.0 2.1 1 1 1 2 2 2 0 DNA primase DnaG DnaB-binding Laminin_G_3 PF13385.6 ABK75794.1 - 1.5e-08 34.9 0.0 3.9e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PAS_3 PF08447.12 ABK75795.1 - 6.5e-14 52.0 0.0 1.3e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 ABK75795.1 - 1.3e-12 47.8 0.0 2.7e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 PAS domain HisKA_3 PF07730.13 ABK75795.1 - 3.7e-09 37.0 1.4 3.7e-09 37.0 1.4 4.3 5 1 0 5 5 5 1 Histidine kinase HATPase_c PF02518.26 ABK75795.1 - 3.2e-08 34.0 0.0 1.1e-06 29.1 0.0 2.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4118 PF13493.6 ABK75795.1 - 8.1e-08 32.0 7.3 8.1e-08 32.0 7.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4118) GAF_2 PF13185.6 ABK75795.1 - 1e-07 32.3 2.1 9.2e-07 29.2 0.3 2.8 2 1 0 2 2 2 1 GAF domain PAS PF00989.25 ABK75795.1 - 1e-07 31.9 0.1 2.8e-07 30.5 0.0 1.9 1 1 0 1 1 1 1 PAS fold PAS_4 PF08448.10 ABK75795.1 - 4.7e-07 30.0 1.1 4.7e-07 30.0 1.1 2.7 2 1 0 2 2 2 1 PAS fold GAF PF01590.26 ABK75795.1 - 2e-06 28.5 0.1 1e-05 26.2 0.0 2.3 2 0 0 2 2 2 1 GAF domain HATPase_c_2 PF13581.6 ABK75795.1 - 5.8e-05 23.0 0.6 0.0021 18.0 0.1 3.1 3 0 0 3 3 3 1 Histidine kinase-like ATPase domain GAF_3 PF13492.6 ABK75795.1 - 0.00054 20.3 0.1 0.29 11.5 0.0 2.8 2 0 0 2 2 2 1 GAF domain PAS_8 PF13188.7 ABK75795.1 - 0.00092 19.2 0.0 0.0031 17.5 0.0 2.0 1 0 0 1 1 1 1 PAS domain BPD_transp_1 PF00528.22 ABK75796.1 - 3.9e-17 62.6 13.5 3.9e-17 62.6 13.5 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF997 PF06196.12 ABK75796.1 - 0.44 10.6 3.7 0.35 10.9 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF997) DUF2786 PF10979.8 ABK75797.1 - 1.9e-15 56.5 2.7 4.4e-15 55.3 2.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2786) DUF4158 PF13700.6 ABK75797.1 - 0.034 14.0 0.8 0.14 11.9 0.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4158) FTR1 PF03239.14 ABK75798.1 - 1.3e-40 139.5 20.7 1.6e-40 139.2 20.7 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family VSP PF03302.13 ABK75798.1 - 0.33 9.7 0.5 0.52 9.1 0.5 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF3087 PF11286.8 ABK75798.1 - 1.3 8.5 4.2 12 5.3 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) DisA-linker PF10635.9 ABK75799.1 - 1.9e-49 167.1 0.3 2.9e-49 166.5 0.3 1.3 1 0 0 1 1 1 1 DisA bacterial checkpoint controller linker region DisA_N PF02457.16 ABK75799.1 - 5.7e-24 84.0 0.0 1.1e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 DisA bacterial checkpoint controller nucleotide-binding HHH_2 PF12826.7 ABK75799.1 - 3.5e-08 33.4 0.4 7.6e-07 29.1 0.0 3.0 4 0 0 4 4 4 1 Helix-hairpin-helix motif HHH PF00633.23 ABK75799.1 - 0.00012 21.7 0.0 0.0083 16.0 0.0 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 ABK75799.1 - 0.11 13.1 0.0 0.37 11.4 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain Helicase_C PF00271.31 ABK75800.1 - 3.1e-17 62.9 0.0 5.4e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 ABK75800.1 - 6.5e-13 49.2 0.5 1.4e-12 48.2 0.5 1.5 1 0 0 1 1 1 1 RecQ zinc-binding GGDEF_2 PF17853.1 ABK75800.1 - 0.064 13.5 0.5 0.14 12.4 0.2 1.8 2 0 0 2 2 2 0 GGDEF-like domain HEM4 PF02602.15 ABK75800.1 - 0.075 12.4 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD HTH_20 PF12840.7 ABK75800.1 - 0.31 11.2 4.1 4.1 7.5 0.1 3.5 4 0 0 4 4 4 0 Helix-turn-helix domain Wzz PF02706.15 ABK75801.1 - 1.3e-08 35.1 0.1 1.3e-08 35.1 0.1 1.7 2 0 0 2 2 2 1 Chain length determinant protein CitMHS PF03600.16 ABK75802.1 - 3.2e-52 177.6 31.6 5.8e-52 176.8 31.6 1.4 1 0 0 1 1 1 1 Citrate transporter ArsB PF02040.15 ABK75802.1 - 5.1e-17 62.3 29.3 6e-17 62.1 29.3 1.0 1 0 0 1 1 1 1 Arsenical pump membrane protein NhaB PF06450.12 ABK75802.1 - 7.2e-08 31.7 2.4 7.2e-08 31.7 2.4 2.7 3 0 0 3 3 3 2 Bacterial Na+/H+ antiporter B (NhaB) GPI2 PF06432.11 ABK75802.1 - 0.18 11.2 0.0 0.18 11.2 0.0 2.9 2 2 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase DUF872 PF05915.12 ABK75802.1 - 8.2 6.6 9.8 7.3 6.8 0.5 2.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DIOX_N PF14226.6 ABK75803.1 - 6.4e-22 78.5 0.0 1e-21 77.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ABK75803.1 - 9.3e-12 45.3 0.0 1.5e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1707 PF08044.11 ABK75804.1 - 2e-17 63.0 5.6 2.7e-17 62.6 5.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1707) DUF2154 PF09922.9 ABK75804.1 - 1.7e-06 27.9 0.1 6.3e-06 26.0 0.0 1.8 1 1 1 2 2 2 1 Cell wall-active antibiotics response 4TMS YvqF Acyl-CoA_dh_1 PF00441.24 ABK75804.1 - 0.0037 17.5 0.3 0.041 14.1 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Peptidase_S8 PF00082.22 ABK75805.1 - 3.1e-40 138.3 4.3 3.7e-39 134.7 4.3 2.0 1 1 0 1 1 1 1 Subtilase family Mrr_N PF14338.6 ABK75805.1 - 0.14 12.3 0.1 0.27 11.4 0.1 1.4 1 0 0 1 1 1 0 Mrr N-terminal domain DUF3027 PF11228.8 ABK75806.1 - 1.3e-80 270.0 0.0 1.6e-80 269.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3027) MFS_1 PF07690.16 ABK75807.1 - 2.6e-40 138.4 46.3 8.7e-40 136.7 36.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 ABK75807.1 - 0.12 11.2 13.0 0.17 10.7 4.5 2.2 1 1 0 2 2 2 0 MFS_1 like family Sugar_tr PF00083.24 ABK75807.1 - 5.4 5.8 22.3 0.038 12.9 7.8 2.3 2 0 0 2 2 2 0 Sugar (and other) transporter Tagatose_6_P_K PF08013.11 ABK75808.1 - 5.5e-193 641.3 0.0 6.3e-193 641.2 0.0 1.0 1 0 0 1 1 1 1 Tagatose 6 phosphate kinase PrgH PF09480.10 ABK75809.1 - 0.19 11.0 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) PS_Dcarbxylase PF02666.15 ABK75810.1 - 2e-31 109.1 0.0 2.1e-30 105.8 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase TetR_C_20 PF17925.1 ABK75812.1 - 1.4e-25 89.7 0.0 3.9e-25 88.2 0.0 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK75812.1 - 1.7e-10 40.5 0.2 3.2e-10 39.6 0.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family Bromo_TP PF07524.13 ABK75812.1 - 0.062 13.3 0.0 7.9 6.6 0.0 2.4 2 0 0 2 2 2 0 Bromodomain associated FeoC PF09012.10 ABK75812.1 - 0.2 11.8 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 FeoC like transcriptional regulator Abhydrolase_3 PF07859.13 ABK75813.1 - 1.2e-59 201.7 0.3 1.5e-59 201.4 0.3 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ABK75813.1 - 7.2e-11 41.6 0.1 1.9e-10 40.3 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 ABK75813.1 - 1e-05 25.1 0.0 8.4e-05 22.1 0.0 2.2 2 1 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 ABK75813.1 - 0.00028 19.7 0.0 0.00047 18.9 0.0 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) DLH PF01738.18 ABK75813.1 - 0.00051 19.7 0.0 0.13 11.8 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Esterase_phd PF10503.9 ABK75813.1 - 0.0079 15.7 0.7 0.023 14.2 0.2 1.9 2 0 0 2 2 2 1 Esterase PHB depolymerase BAAT_C PF08840.11 ABK75813.1 - 0.04 13.8 0.0 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Acetyltransf_3 PF13302.7 ABK75814.1 - 3.5e-27 95.8 0.0 4e-27 95.6 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ABK75814.1 - 3.3e-07 30.5 0.0 4.2e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 ABK75814.1 - 0.00057 19.6 0.0 0.0059 16.3 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ABK75814.1 - 0.0025 18.0 0.0 0.003 17.7 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DHquinase_II PF01220.19 ABK75816.1 - 6.8e-33 113.3 0.0 9e-33 112.9 0.0 1.1 1 0 0 1 1 1 1 Dehydroquinase class II NUDIX PF00293.28 ABK75817.1 - 1e-19 70.9 0.1 1.7e-19 70.2 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain MlaD PF02470.20 ABK75818.1 - 1.5e-14 54.1 0.1 2.5e-14 53.3 0.1 1.4 1 0 0 1 1 1 1 MlaD protein Mce4_CUP1 PF11887.8 ABK75818.1 - 8.9e-05 22.1 1.3 0.00015 21.3 1.3 1.3 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative PriA_3primeBD PF17764.1 ABK75820.1 - 6.9e-14 51.5 0.0 1.5e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 3′ DNA-binding domain (3′BD) C1_1 PF00130.22 ABK75820.1 - 1.7 8.6 6.8 9.3 6.2 7.1 2.0 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Sdh_cyt PF01127.22 ABK75821.1 - 1.4e-13 50.9 9.0 1.6e-13 50.7 7.9 1.5 1 1 1 2 2 2 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit CybS PF05328.12 ABK75821.1 - 6.9e-05 22.6 0.3 0.00015 21.5 0.3 1.6 1 1 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Abhydrolase_1 PF00561.20 ABK75822.1 - 1.8e-23 83.5 0.0 1e-22 81.1 0.1 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK75822.1 - 8e-20 72.4 6.9 1e-19 72.1 6.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK75822.1 - 1.9e-10 40.4 0.0 8.2e-10 38.4 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 ABK75822.1 - 0.0078 15.9 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Gln-synt_C PF00120.24 ABK75823.1 - 1.2e-77 261.3 0.0 1.8e-77 260.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain FtsK_alpha PF17854.1 ABK75823.1 - 0.027 14.6 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 FtsK alpha domain Gln-synt_N_2 PF16952.5 ABK75823.1 - 0.061 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Glutamine synthetase N-terminal domain MOSC PF03473.17 ABK75824.1 - 5.1e-10 39.5 0.0 9.6e-10 38.6 0.0 1.5 1 1 0 1 1 1 1 MOSC domain WXG100 PF06013.12 ABK75825.1 - 6.3e-16 58.4 8.5 7e-16 58.2 8.5 1.0 1 0 0 1 1 1 1 Proteins of 100 residues with WXG Mobilization_B PF17511.2 ABK75825.1 - 0.0012 19.3 6.0 0.0013 19.1 6.0 1.2 1 0 0 1 1 1 1 Mobilization protein B DUF4175 PF13779.6 ABK75825.1 - 0.0033 15.4 4.4 0.0034 15.4 4.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) HR1 PF02185.16 ABK75825.1 - 0.0035 17.4 2.1 0.0082 16.2 1.5 1.8 2 0 0 2 2 2 1 Hr1 repeat TPR_MLP1_2 PF07926.12 ABK75825.1 - 0.0041 17.2 6.3 0.041 14.0 4.2 2.1 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein Syntaxin PF00804.25 ABK75825.1 - 0.0054 16.4 1.0 0.0066 16.1 1.0 1.0 1 0 0 1 1 1 1 Syntaxin PPE PF00823.19 ABK75825.1 - 0.0086 16.2 5.6 0.011 15.8 5.6 1.2 1 0 0 1 1 1 1 PPE family Lant_dehydr_C PF14028.6 ABK75825.1 - 0.024 14.2 2.2 0.026 14.1 2.2 1.1 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term DUF725 PF05267.12 ABK75825.1 - 0.037 14.0 1.5 0.21 11.6 1.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF725) DUF883 PF05957.13 ABK75825.1 - 0.053 14.1 2.7 0.07 13.7 2.7 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) MRP-L28 PF09812.9 ABK75825.1 - 0.059 13.5 2.7 0.067 13.3 2.7 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 T7SS_ESX_EspC PF10824.8 ABK75825.1 - 0.063 13.8 4.4 0.076 13.5 4.4 1.2 1 0 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm TraG_N PF07916.11 ABK75825.1 - 0.15 10.9 1.7 0.17 10.7 1.7 1.0 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Tape_meas_lam_C PF09718.10 ABK75825.1 - 0.2 11.8 3.1 0.83 9.8 1.2 2.2 1 1 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) CP_ATPgrasp_2 PF14403.6 ABK75826.1 - 1.6e-127 425.5 0.0 2.7e-127 424.8 0.0 1.3 1 0 0 1 1 1 1 Circularly permuted ATP-grasp type 2 CP_ATPgrasp_1 PF04174.13 ABK75826.1 - 2.1e-122 408.3 0.0 3.5e-122 407.6 0.0 1.4 1 0 0 1 1 1 1 A circularly permuted ATPgrasp Alpha-E PF04168.12 ABK75826.1 - 5.5e-68 229.9 6.2 1.1e-67 228.9 6.2 1.5 1 0 0 1 1 1 1 A predicted alpha-helical domain with a conserved ER motif. DUF4908 PF16252.5 ABK75826.1 - 0.099 12.2 0.8 0.28 10.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4908) CitG PF01874.16 ABK75827.1 - 3.3e-70 236.9 8.5 3.8e-70 236.7 8.5 1.0 1 0 0 1 1 1 1 ATP:dephospho-CoA triphosphoribosyl transferase Abhydrolase_1 PF00561.20 ABK75828.1 - 1.2e-20 74.3 0.0 8.6e-13 48.5 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK75828.1 - 1.3e-20 75.0 2.3 1.5e-20 74.7 2.3 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK75828.1 - 9.3e-13 48.0 0.2 2.4e-12 46.6 0.2 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 ABK75828.1 - 1.2e-05 25.3 0.0 2.9e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Patatin PF01734.22 ABK75828.1 - 0.00083 19.6 0.0 0.0011 19.2 0.0 1.2 1 0 0 1 1 1 1 Patatin-like phospholipase Thioesterase PF00975.20 ABK75828.1 - 0.011 15.8 0.0 0.014 15.5 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Phage_holin_3_6 PF07332.11 ABK75829.1 - 1.3e-32 112.2 8.9 1.5e-32 112.0 8.9 1.0 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III Tetraspanin PF00335.20 ABK75829.1 - 2.9e-05 23.9 0.1 3.3e-05 23.7 0.1 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF2207 PF09972.9 ABK75829.1 - 0.012 14.4 0.5 0.014 14.2 0.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ATP1G1_PLM_MAT8 PF02038.16 ABK75829.1 - 0.016 14.6 0.1 0.016 14.6 0.1 2.3 2 1 1 3 3 3 0 ATP1G1/PLM/MAT8 family DUF4407 PF14362.6 ABK75829.1 - 0.026 13.9 2.5 0.032 13.6 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fuseless PF15993.5 ABK75829.1 - 0.034 13.4 0.0 0.039 13.2 0.0 1.0 1 0 0 1 1 1 0 Fuseless SieB PF14163.6 ABK75829.1 - 0.052 13.0 0.5 0.076 12.5 0.5 1.2 1 0 0 1 1 1 0 Super-infection exclusion protein B FA_desaturase PF00487.24 ABK75829.1 - 0.12 12.2 0.4 0.12 12.1 0.4 1.1 1 0 0 1 1 1 0 Fatty acid desaturase DUF5305 PF17231.2 ABK75829.1 - 0.36 10.2 1.5 2.7 7.3 0.0 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5305) DUF1676 PF07898.13 ABK75829.1 - 1.9 8.5 5.3 2.4 8.2 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) SLATT_1 PF18181.1 ABK75829.1 - 4.5 7.2 5.3 6.4 6.7 5.2 1.5 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 HpcH_HpaI PF03328.14 ABK75830.1 - 7e-42 143.0 0.1 2.2e-41 141.4 0.0 1.7 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 ABK75830.1 - 1.3e-05 24.5 0.0 0.00023 20.5 0.0 2.1 2 0 0 2 2 2 1 C-C_Bond_Lyase of the TIM-Barrel fold Malate_synthase PF01274.22 ABK75830.1 - 0.00017 20.0 0.0 0.31 9.3 0.0 2.1 2 0 0 2 2 2 2 Malate synthase LEA_6 PF10714.9 ABK75830.1 - 0.04 14.0 0.0 0.075 13.1 0.0 1.5 1 0 0 1 1 1 0 Late embryogenesis abundant protein 18 MFS_1 PF07690.16 ABK75831.1 - 4e-33 114.8 74.1 2.6e-26 92.4 54.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ABK75831.1 - 0.00039 19.1 12.0 0.00039 19.1 12.0 2.7 1 1 1 2 2 2 1 MFS/sugar transport protein LamB_YcsF PF03746.16 ABK75832.1 - 1.7e-80 270.2 0.1 1.9e-80 270.0 0.1 1.0 1 0 0 1 1 1 1 LamB/YcsF family Circo_capsid PF02443.15 ABK75833.1 - 7.2 6.1 9.7 8 6.0 9.7 1.1 1 0 0 1 1 1 0 Circovirus capsid protein DUF1275 PF06912.11 ABK75834.1 - 6.3e-34 117.6 25.3 7.3e-34 117.4 25.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) TauE PF01925.19 ABK75834.1 - 0.023 14.4 27.6 29 4.2 4.7 2.7 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE OATP PF03137.20 ABK75834.1 - 3.7 5.7 8.0 0.38 9.0 2.3 1.9 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Oxidored_q6 PF01058.22 ABK75836.1 - 1.4e-32 112.3 0.0 1.9e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit NiFe_hyd_SSU_C PF14720.6 ABK75836.1 - 3.8e-21 75.2 2.8 6.7e-21 74.4 2.8 1.4 1 0 0 1 1 1 1 NiFe/NiFeSe hydrogenase small subunit C-terminal DUF3710 PF12502.8 ABK75837.1 - 4.7e-56 189.2 2.3 4.7e-56 189.2 2.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3710) Ribosomal_60s PF00428.19 ABK75837.1 - 0.95 10.1 9.6 0.35 11.5 2.3 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein AA_permease PF00324.21 ABK75839.1 - 2.8e-104 349.4 45.6 3.5e-104 349.1 45.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ABK75839.1 - 6.7e-41 140.5 51.1 8.2e-41 140.2 51.1 1.0 1 0 0 1 1 1 1 Amino acid permease Nterm_IS4 PF13006.7 ABK75839.1 - 8 6.7 6.9 16 5.8 0.5 3.4 3 0 0 3 3 3 0 Insertion element 4 transposase N-terminal ADH_zinc_N_2 PF13602.6 ABK75840.1 - 3.7e-13 50.7 2.6 4.8e-13 50.3 0.1 2.4 2 2 1 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ABK75840.1 - 6.6e-10 39.1 0.4 1.3e-09 38.1 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ABK75840.1 - 3.7e-09 36.5 0.0 1e-08 35.0 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ABK75841.1 - 3.4e-23 82.1 1.2 5.3e-23 81.4 1.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ABK75841.1 - 4.1e-17 63.5 0.3 9.7e-17 62.3 0.3 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ABK75841.1 - 1.8e-12 47.1 0.0 6.7e-12 45.3 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 ABK75841.1 - 0.00059 19.7 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase YbjN PF10722.9 ABK75842.1 - 0.063 13.3 0.1 1.7 8.7 0.0 2.1 2 0 0 2 2 2 0 Putative bacterial sensory transduction regulator Inositol_P PF00459.25 ABK75845.1 - 2.1e-28 99.6 0.1 6.6e-15 55.3 0.0 2.0 2 0 0 2 2 2 2 Inositol monophosphatase family MlaD PF02470.20 ABK75846.1 - 7e-18 64.7 0.3 1.3e-17 63.8 0.3 1.5 1 0 0 1 1 1 1 MlaD protein Mce4_CUP1 PF11887.8 ABK75846.1 - 4.3e-06 26.4 0.6 5.8e-06 25.9 0.6 1.1 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative CcmE PF03100.15 ABK75846.1 - 0.015 15.2 0.3 0.026 14.5 0.3 1.3 1 0 0 1 1 1 0 CcmE Mod_r PF07200.13 ABK75846.1 - 0.058 13.5 0.0 0.091 12.9 0.0 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein FA_desaturase PF00487.24 ABK75848.1 - 2.4e-33 116.0 5.5 3.2e-33 115.6 5.5 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Polyketide_cyc2 PF10604.9 ABK75849.1 - 8.2e-05 22.9 0.2 0.00013 22.3 0.2 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport ECH_1 PF00378.20 ABK75850.1 - 8.3e-53 179.3 0.0 9.9e-53 179.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK75850.1 - 2.6e-27 96.2 0.2 8.9e-23 81.3 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Transglut_core PF01841.19 ABK75852.1 - 3e-27 95.3 0.2 4.9e-27 94.6 0.2 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily Bact_transglu_N PF08379.10 ABK75852.1 - 2.8e-19 69.8 1.8 5.2e-19 68.9 1.8 1.4 1 0 0 1 1 1 1 Bacterial transglutaminase-like N-terminal region DUF553 PF04473.12 ABK75852.1 - 0.0035 16.9 0.0 0.052 13.1 0.0 2.1 1 1 1 2 2 2 1 Transglutaminase-like domain LamB_YcsF PF03746.16 ABK75853.1 - 1.6e-101 339.0 0.2 1.8e-101 338.8 0.2 1.0 1 0 0 1 1 1 1 LamB/YcsF family DUF3929 PF13066.6 ABK75853.1 - 0.063 13.3 0.5 0.13 12.3 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3929) DUF3168 PF11367.8 ABK75853.1 - 0.82 9.9 5.3 0.55 10.4 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3168) Mob_synth_C PF06463.13 ABK75854.1 - 3.5e-37 127.2 0.0 4.9e-37 126.7 0.0 1.2 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 ABK75854.1 - 4.1e-25 89.1 0.0 6e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 ABK75854.1 - 4.1e-05 23.9 0.0 6.4e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 ABK75854.1 - 0.00051 20.2 0.0 0.00099 19.2 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain ABC_tran PF00005.27 ABK75855.1 - 2.4e-30 105.8 0.0 3.5e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 ABK75855.1 - 0.00015 22.2 0.1 0.00028 21.3 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ABK75855.1 - 0.00015 22.1 0.0 0.0003 21.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 ABK75855.1 - 0.00016 21.6 0.0 0.015 15.1 0.0 2.1 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ABK75855.1 - 0.0012 18.6 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.6 ABK75855.1 - 0.0019 18.5 0.0 0.0034 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ABK75855.1 - 0.0071 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 ABK75855.1 - 0.0086 16.6 0.0 0.012 16.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 ABK75855.1 - 0.021 14.3 0.1 0.39 10.1 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 ABK75855.1 - 0.037 13.9 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_33 PF13671.6 ABK75855.1 - 0.055 13.6 0.1 0.11 12.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ABK75855.1 - 0.088 12.5 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ABK75855.1 - 0.093 12.6 0.0 0.65 9.9 0.0 2.2 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.22 ABK75855.1 - 0.1 11.7 0.1 0.19 10.9 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain ABC_ATPase PF09818.9 ABK75855.1 - 0.14 10.9 0.1 0.87 8.3 0.0 2.0 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA PF00004.29 ABK75855.1 - 0.16 12.4 0.0 0.41 11.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 ABK75855.1 - 0.23 11.5 0.0 0.53 10.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain Polysacc_deac_1 PF01522.21 ABK75856.1 - 1.8e-12 47.2 0.0 3.1e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF4229 PF14012.6 ABK75858.1 - 5.1e-22 77.7 10.6 6.3e-22 77.5 10.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4229) BNIP3 PF06553.12 ABK75858.1 - 0.42 10.3 0.1 0.42 10.3 0.1 1.4 2 0 0 2 2 2 0 BNIP3 Asp_decarbox PF02261.16 ABK75859.1 - 2.2e-47 159.7 1.2 2.6e-47 159.5 1.2 1.0 1 0 0 1 1 1 1 Aspartate decarboxylase DUF1513 PF07433.11 ABK75859.1 - 0.0028 16.8 0.2 0.0032 16.6 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1513) DUF432 PF04254.13 ABK75859.1 - 0.15 12.2 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF432) FGGY_C PF02782.16 ABK75860.1 - 9e-32 110.4 0.1 1.3e-31 109.9 0.1 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 ABK75860.1 - 7.4e-20 71.5 0.0 1.2e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain CLP_protease PF00574.23 ABK75861.1 - 1.8e-75 252.8 0.1 2.2e-75 252.6 0.1 1.0 1 0 0 1 1 1 1 Clp protease Peptidase_S49 PF01343.18 ABK75861.1 - 0.074 13.0 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Peptidase family S49 BPD_transp_2 PF02653.16 ABK75862.1 - 3.5e-59 200.2 42.3 3.5e-59 200.2 42.3 1.3 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component DUF543 PF04418.12 ABK75862.1 - 8.5 6.4 12.8 46 4.1 0.0 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF543) AhpC-TSA PF00578.21 ABK75863.1 - 1e-31 109.4 0.0 1.2e-31 109.2 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ABK75863.1 - 4.7e-15 55.6 0.0 5.6e-15 55.3 0.0 1.0 1 0 0 1 1 1 1 Redoxin BPD_transp_1 PF00528.22 ABK75864.1 - 3.7e-16 59.4 11.7 3.7e-16 59.4 11.7 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component ABC2_membrane_5 PF13346.6 ABK75864.1 - 0.012 15.2 5.9 0.028 14.0 0.3 2.4 2 0 0 2 2 2 0 ABC-2 family transporter protein LysE PF01810.18 ABK75865.1 - 2.4e-28 98.9 15.0 3e-28 98.6 15.0 1.1 1 0 0 1 1 1 1 LysE type translocator Molybdopterin PF00384.22 ABK75866.1 - 8e-38 130.5 0.0 1.5e-37 129.6 0.0 1.4 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 ABK75866.1 - 1.1e-16 60.9 0.0 2.2e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 ABK75866.1 - 2.1e-11 43.6 1.9 3.6e-11 42.9 1.9 1.4 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain NmrA PF05368.13 ABK75867.1 - 0.0001 22.0 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family SnoaL_4 PF13577.6 ABK75868.1 - 1e-27 96.7 1.4 1.4e-27 96.3 1.4 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 ABK75868.1 - 5.2e-07 30.2 1.1 6.9e-07 29.9 1.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 ABK75868.1 - 0.031 14.7 1.3 0.055 13.9 1.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) ABC_membrane PF00664.23 ABK75869.1 - 9.4e-47 159.9 9.8 1.3e-46 159.5 9.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 ABK75869.1 - 1.4e-29 103.3 0.0 2.5e-29 102.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ABK75869.1 - 2.5e-09 36.9 0.0 2.1e-06 27.4 0.0 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ABK75869.1 - 0.00086 19.0 0.1 0.0028 17.3 0.1 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF87 PF01935.17 ABK75869.1 - 0.0036 17.4 1.0 0.0064 16.6 1.0 1.3 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_23 PF13476.6 ABK75869.1 - 0.022 15.3 0.0 0.033 14.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ABK75869.1 - 0.032 13.5 0.0 0.068 12.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin RsgA_GTPase PF03193.16 ABK75869.1 - 0.032 14.1 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 ABK75869.1 - 0.063 12.8 0.5 0.2 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain Colicin PF01024.19 ABK75869.1 - 0.11 12.4 0.9 0.32 10.9 0.9 1.8 1 0 0 1 1 1 0 Colicin pore forming domain AAA_21 PF13304.6 ABK75869.1 - 0.11 12.2 0.1 0.36 10.6 0.1 1.7 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 ABK75869.1 - 0.12 12.5 0.1 0.32 11.1 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF4157 PF13699.6 ABK75869.1 - 0.51 10.6 2.3 0.57 10.4 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4157) Phage_int_SAM_1 PF02899.17 ABK75870.1 - 1.1e-08 35.3 0.5 2.5e-08 34.1 0.5 1.7 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_integrase PF00589.22 ABK75870.1 - 8.1e-06 25.7 0.0 0.00087 19.1 0.0 3.1 2 1 0 2 2 2 1 Phage integrase family TraI_2B PF18340.1 ABK75870.1 - 0.044 13.9 0.0 1.7 8.7 0.1 3.0 3 0 0 3 3 3 0 DNA relaxase TraI 2B/2B-like domain Polysacc_deac_1 PF01522.21 ABK75872.1 - 1.2e-08 34.9 0.0 2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ABK75872.1 - 0.031 13.5 0.0 0.073 12.3 0.0 1.7 1 1 0 1 1 1 0 Glycosyl hydrolase family 57 Psu PF07455.11 ABK75872.1 - 0.14 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Phage polarity suppression protein (Psu) Linocin_M18 PF04454.12 ABK75872.1 - 0.15 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Encapsulating protein for peroxidase Staph_haemo PF05480.11 ABK75872.1 - 0.22 11.3 0.0 0.46 10.3 0.0 1.4 1 0 0 1 1 1 0 Staphylococcus haemolytic protein TspO_MBR PF03073.15 ABK75873.1 - 1.9e-33 115.4 2.3 2.3e-33 115.1 2.3 1.0 1 0 0 1 1 1 1 TspO/MBR family LCM PF04072.14 ABK75874.1 - 1e-45 156.0 1.4 1.5e-45 155.5 1.4 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase EamA PF00892.20 ABK75875.1 - 6.7e-15 55.5 27.1 1.8e-11 44.4 10.5 2.1 2 0 0 2 2 2 2 EamA-like transporter family TetR_N PF00440.23 ABK75876.1 - 6.3e-17 61.1 0.1 1.1e-16 60.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_IclR PF09339.10 ABK75876.1 - 0.018 14.8 0.0 0.047 13.5 0.0 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_23 PF13384.6 ABK75876.1 - 0.018 14.8 0.0 0.073 12.9 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_11 PF08279.12 ABK75876.1 - 0.069 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 HTH domain HTH_22 PF13309.6 ABK75876.1 - 0.069 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 HTH domain UPF0122 PF04297.14 ABK75876.1 - 0.11 12.7 0.0 0.28 11.4 0.0 1.6 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like HTH_18 PF12833.7 ABK75876.1 - 0.12 12.7 0.0 0.33 11.3 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain Aldo_ket_red PF00248.21 ABK75877.1 - 8.2e-41 140.1 0.0 4.4e-40 137.7 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family TPR_14 PF13428.6 ABK75877.1 - 0.1 13.5 0.0 0.36 11.8 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat HNH_repeat PF18780.1 ABK75877.1 - 0.11 12.3 0.1 0.35 10.7 0.0 1.9 2 0 0 2 2 2 0 Homing endonuclease repeat Aldedh PF00171.22 ABK75878.1 - 1.8e-131 438.9 2.0 2e-131 438.7 2.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family baeRF_family2 PF18844.1 ABK75878.1 - 0.034 14.2 0.7 0.034 14.2 0.7 2.9 3 1 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 2 Aconitase_C PF00694.19 ABK75879.1 - 1.4e-09 38.4 0.0 1.8e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Aconitase C-terminal domain AsiA PF09010.10 ABK75879.1 - 0.19 11.9 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 Anti-Sigma Factor A Glycos_transf_2 PF00535.26 ABK75880.1 - 8.9e-21 74.4 0.0 1.2e-20 74.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ABK75880.1 - 2.4e-10 40.7 2.1 6.7e-10 39.2 2.1 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Osmo_MPGsynth PF09488.10 ABK75880.1 - 0.032 12.9 0.0 0.042 12.5 0.0 1.1 1 0 0 1 1 1 0 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) Glyco_tranf_2_4 PF13704.6 ABK75880.1 - 0.044 14.3 0.0 0.1 13.2 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase family 2 AMP-binding PF00501.28 ABK75882.1 - 1.2e-40 139.4 0.1 1.6e-40 139.0 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK75882.1 - 4.2e-05 24.4 1.3 9.7e-05 23.3 1.3 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 ABK75882.1 - 0.00018 21.8 0.0 0.00039 20.7 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3830 PF12903.7 ABK75883.1 - 2.9e-66 221.6 0.0 3.4e-66 221.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3830) Cyclophil_like PF04126.13 ABK75883.1 - 0.11 12.4 0.0 8 6.3 0.0 2.1 2 0 0 2 2 2 0 Cyclophilin-like Auts2 PF15336.6 ABK75884.1 - 0.2 11.8 0.2 0.22 11.6 0.2 1.0 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein BPD_transp_1 PF00528.22 ABK75885.1 - 2.4e-12 47.0 18.7 3.1e-12 46.6 18.7 1.2 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Carboxyl_trans PF01039.22 ABK75886.1 - 2.2e-142 475.2 0.0 2.6e-142 475.0 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 ABK75886.1 - 0.0079 15.7 1.0 0.3 10.5 0.0 2.4 2 0 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) ECH_1 PF00378.20 ABK75886.1 - 0.092 12.0 0.3 0.37 10.1 0.0 2.0 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase Mu-transpos_C PF09299.11 ABK75886.1 - 0.18 11.8 0.0 0.59 10.1 0.0 1.8 1 0 0 1 1 1 0 Mu transposase, C-terminal Ribosomal_L21p PF00829.21 ABK75887.1 - 6.7e-34 116.2 2.6 7.8e-34 116.0 2.6 1.0 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein CH_2 PF06294.11 ABK75887.1 - 0.018 15.2 0.0 0.025 14.7 0.0 1.2 1 0 0 1 1 1 0 CH-like domain in sperm protein CSD PF00313.22 ABK75888.1 - 1.5e-31 108.1 0.2 1.6e-31 108.0 0.2 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 ABK75888.1 - 0.00016 21.3 0.1 0.00021 20.9 0.1 1.3 1 0 0 1 1 1 1 Ribonuclease B OB domain TetR_N PF00440.23 ABK75889.1 - 1.6e-14 53.4 0.5 2.8e-14 52.6 0.5 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 ABK75889.1 - 2.5e-08 34.2 2.1 3.8e-08 33.6 0.5 2.1 2 1 1 3 3 3 1 Tetracyclin repressor-like, C-terminal domain SBP_bac_3 PF00497.20 ABK75889.1 - 0.056 12.9 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 TetR_C_14 PF17754.1 ABK75889.1 - 0.15 12.0 2.3 2.9 7.9 0.1 2.9 3 0 0 3 3 3 0 MftR C-terminal domain AbiH PF14253.6 ABK75889.1 - 0.22 11.4 0.0 0.26 11.1 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH MFS_1 PF07690.16 ABK75891.1 - 2.7e-31 108.8 73.7 3.7e-25 88.6 42.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK75891.1 - 1.3e-26 93.5 27.5 9e-23 80.8 7.3 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter DUF4271 PF14093.6 ABK75891.1 - 0.26 11.2 2.3 0.37 10.7 1.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) Esterase PF00756.20 ABK75892.1 - 3.4e-69 233.3 0.1 4e-69 233.0 0.1 1.0 1 0 0 1 1 1 1 Putative esterase DsbB PF02600.16 ABK75892.1 - 0.1 13.0 0.1 0.22 12.0 0.1 1.5 1 0 0 1 1 1 0 Disulfide bond formation protein DsbB GerE PF00196.19 ABK75893.1 - 4.7e-16 58.1 0.0 9.5e-16 57.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family AAA_16 PF13191.6 ABK75893.1 - 5.7e-10 39.8 6.2 5.7e-10 39.8 6.2 4.8 3 2 1 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 ABK75893.1 - 3e-09 37.2 1.3 3.3e-07 30.7 1.3 2.7 1 1 0 1 1 1 1 AAA domain Sigma70_r4_2 PF08281.12 ABK75893.1 - 1.3e-05 24.7 0.0 4.5e-05 23.0 0.0 2.0 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_30 PF13556.6 ABK75893.1 - 0.00018 21.2 0.1 0.00088 19.0 0.1 2.2 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain AAA_30 PF13604.6 ABK75893.1 - 0.00024 20.9 0.6 0.00088 19.0 0.6 2.0 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 ABK75893.1 - 0.00085 19.3 0.6 0.011 15.6 0.1 2.6 3 0 0 3 3 2 1 NACHT domain HTH_38 PF13936.6 ABK75893.1 - 0.0017 18.1 0.0 0.0053 16.5 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 ABK75893.1 - 0.0029 17.1 0.1 0.021 14.4 0.0 2.5 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding TPR_12 PF13424.6 ABK75893.1 - 0.017 15.4 29.1 0.17 12.2 3.4 6.3 4 2 3 7 7 6 0 Tetratricopeptide repeat TsaE PF02367.17 ABK75893.1 - 0.019 15.0 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TPR_4 PF07721.14 ABK75893.1 - 0.02 15.5 2.5 0.02 15.5 2.5 12.5 16 0 0 16 16 9 0 Tetratricopeptide repeat AAA_28 PF13521.6 ABK75893.1 - 0.024 14.9 0.0 0.17 12.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 ABK75893.1 - 0.026 14.4 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea HTH_10 PF04967.12 ABK75893.1 - 0.047 13.5 0.0 0.29 11.0 0.0 2.3 2 0 0 2 2 2 0 HTH DNA binding domain TPR_21 PF09976.9 ABK75893.1 - 0.053 13.2 8.4 0.12 12.1 0.3 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain AAA PF00004.29 ABK75893.1 - 0.062 13.7 0.1 0.43 11.0 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 ABK75893.1 - 0.089 13.1 1.7 0.24 11.7 0.1 2.5 3 0 0 3 3 2 0 AAA domain DUF3775 PF12616.8 ABK75893.1 - 0.093 12.8 1.1 0.49 10.5 0.2 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3775) HTH_40 PF14493.6 ABK75893.1 - 0.17 12.4 0.0 0.41 11.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain TPR_19 PF14559.6 ABK75893.1 - 6.1 7.4 22.6 1.2 9.7 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 ABK75893.1 - 8.5 6.8 18.7 29 5.1 0.0 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat BCSC_C PF05420.11 ABK75894.1 - 0.094 11.8 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Cellulose synthase operon protein C C-terminus (BCSC_C) NMT1 PF09084.11 ABK75895.1 - 2.3e-09 37.5 0.0 3.6e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 ABK75895.1 - 4.5e-06 26.4 0.0 6.8e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 ABK75895.1 - 0.00053 19.5 0.0 0.00078 18.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 VitK2_biosynth PF02621.14 ABK75895.1 - 0.0065 16.0 0.0 1 8.9 0.0 2.2 2 0 0 2 2 2 2 Menaquinone biosynthesis NMT1_3 PF16868.5 ABK75895.1 - 0.025 14.0 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 NMT1-like family FCD PF07729.12 ABK75896.1 - 2.6e-22 79.5 1.5 4.1e-22 78.9 1.5 1.3 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 ABK75896.1 - 1.3e-20 72.8 0.3 3.4e-20 71.4 0.1 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_41 PF14502.6 ABK75896.1 - 2.2e-05 24.0 0.0 4.9e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Rrf2 PF02082.20 ABK75896.1 - 0.0043 17.4 0.0 0.0093 16.3 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator HTH_11 PF08279.12 ABK75896.1 - 0.0076 16.2 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 HTH domain HTH_DeoR PF08220.12 ABK75896.1 - 0.038 13.7 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_Crp_2 PF13545.6 ABK75896.1 - 0.045 13.7 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain MFS_1 PF07690.16 ABK75897.1 - 2e-30 105.9 85.2 1.1e-24 87.1 48.5 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK75897.1 - 3.5e-23 82.2 7.9 3.5e-23 82.2 7.9 2.2 1 1 1 2 2 2 1 Sugar (and other) transporter Nuc_H_symport PF03825.16 ABK75897.1 - 0.00019 20.6 7.5 0.00019 20.6 7.5 2.0 1 1 1 2 2 2 1 Nucleoside H+ symporter 2TM PF13239.6 ABK75897.1 - 0.04 14.2 8.9 0.83 10.0 1.4 3.4 2 1 0 2 2 2 0 2TM domain Toxin_GhoT_OrtT PF10753.9 ABK75898.1 - 0.011 15.9 1.5 1.3 9.3 0.0 2.2 2 0 0 2 2 2 0 Toxin GhoT_OrtT TctB PF07331.11 ABK75898.1 - 0.024 14.9 4.2 0.028 14.7 4.2 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family PepSY_TM PF03929.16 ABK75898.1 - 0.18 11.4 3.6 0.21 11.2 3.6 1.0 1 0 0 1 1 1 0 PepSY-associated TM region DUF4418 PF14387.6 ABK75898.1 - 0.25 11.6 5.3 1.8 8.8 5.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4418) DUF983 PF06170.12 ABK75898.1 - 0.42 11.1 5.1 0.15 12.5 1.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF983) Neurensin PF14927.6 ABK75898.1 - 0.88 9.3 5.3 0.16 11.6 1.0 1.9 1 1 1 2 2 2 0 Neurensin DUF2304 PF10066.9 ABK75898.1 - 1.1 9.4 6.2 5.4 7.3 6.0 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) LCM PF04072.14 ABK75899.1 - 3.4e-15 56.5 0.0 8.1e-15 55.2 0.0 1.6 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Phage_holin_3_6 PF07332.11 ABK75900.1 - 3.8 7.6 13.2 4.9 7.2 13.2 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Radical_SAM PF04055.21 ABK75902.1 - 9.1e-19 68.4 0.0 1.3e-18 67.9 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily HemN_C PF06969.16 ABK75902.1 - 1.7e-06 28.0 2.0 3.8e-06 26.9 2.0 1.6 1 0 0 1 1 1 1 HemN C-terminal domain zf-H2C2_5 PF13909.6 ABK75902.1 - 0.19 11.5 0.1 0.34 10.7 0.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc-finger domain Peptidase_M20 PF01546.28 ABK75903.1 - 1.7e-11 44.2 0.0 2.5e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ABK75903.1 - 1e-10 41.5 0.0 1.5e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain TetR_N PF00440.23 ABK75904.1 - 9.9e-17 60.5 0.0 2.3e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family PPK2 PF03976.14 ABK75905.1 - 7.8e-67 225.1 0.1 1e-66 224.7 0.1 1.1 1 0 0 1 1 1 1 Polyphosphate kinase 2 (PPK2) DUF3113 PF11310.8 ABK75905.1 - 0.18 11.8 0.3 5 7.1 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3113) LIP PF03583.14 ABK75906.1 - 6.2e-86 288.3 0.0 7.9e-86 287.9 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 ABK75906.1 - 0.0047 16.4 0.4 0.046 13.2 0.2 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family ABC_tran PF00005.27 ABK75908.1 - 1e-31 110.2 0.0 1.6e-31 109.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter OB_MalK PF17912.1 ABK75908.1 - 1.2e-06 29.3 0.1 4.2e-06 27.5 0.1 2.1 1 0 0 1 1 1 1 MalK OB fold domain CysA_C_terminal PF17850.1 ABK75908.1 - 6.7e-06 26.6 1.0 4.5e-05 23.9 0.5 2.6 3 0 0 3 3 2 1 CysA C-terminal regulatory domain AAA_21 PF13304.6 ABK75908.1 - 1.3e-05 25.2 0.1 0.12 12.1 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system TOBE_2 PF08402.10 ABK75908.1 - 4.3e-05 23.6 0.7 0.00011 22.3 0.7 1.8 1 0 0 1 1 1 1 TOBE domain AAA_22 PF13401.6 ABK75908.1 - 0.00063 20.0 0.0 0.00091 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 ABK75908.1 - 0.0042 17.0 0.0 0.0064 16.4 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 ABK75908.1 - 0.005 16.8 0.1 0.0098 15.8 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 ABK75908.1 - 0.0068 16.8 0.4 0.012 15.9 0.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 ABK75908.1 - 0.013 15.7 0.7 0.063 13.4 0.7 2.1 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ABK75908.1 - 0.013 16.0 0.0 0.021 15.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ABK75908.1 - 0.023 14.3 0.3 0.083 12.5 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 ABK75908.1 - 0.058 13.1 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ABK75908.1 - 0.062 13.5 0.7 0.12 12.6 0.2 1.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 ABK75908.1 - 0.066 13.6 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 ABK75908.1 - 0.071 12.8 0.0 0.099 12.3 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain DUF865 PF05906.11 ABK75908.1 - 0.14 12.0 0.3 11 5.9 0.1 2.5 2 0 0 2 2 2 0 Herpesvirus-7 repeat of unknown function (DUF865) SMC_N PF02463.19 ABK75908.1 - 0.15 11.5 0.0 9.7 5.5 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF3043 PF11241.8 ABK75909.1 - 1.1e-57 194.9 20.4 4.5e-57 192.8 20.4 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3043) RuvB_N PF05496.12 ABK75910.1 - 1.4e-73 245.9 0.0 3.2e-73 244.7 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_4 PF17864.1 ABK75910.1 - 1.2e-30 105.1 1.4 2.4e-30 104.1 1.4 1.6 1 0 0 1 1 1 1 RuvB AAA lid domain RuvB_C PF05491.13 ABK75910.1 - 6.9e-24 83.5 0.0 1.2e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 RuvB C-terminal winged helix domain AAA PF00004.29 ABK75910.1 - 9.1e-17 61.7 0.0 1.9e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 ABK75910.1 - 3.8e-06 26.4 0.6 1.6e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_5 PF07728.14 ABK75910.1 - 6.9e-06 26.1 0.3 0.00031 20.7 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ABK75910.1 - 1.3e-05 25.6 2.2 0.0001 22.7 0.2 2.6 2 1 1 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.21 ABK75910.1 - 0.00016 21.2 1.0 0.1 11.9 0.1 2.6 1 1 2 3 3 3 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 ABK75910.1 - 0.0011 18.7 0.0 1.5 8.5 0.0 2.3 1 1 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 ABK75910.1 - 0.0028 18.0 0.5 1.3 9.3 0.0 2.5 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.22 ABK75910.1 - 0.0043 17.4 0.0 0.0072 16.7 0.0 1.3 1 0 0 1 1 1 1 RNA helicase AAA_3 PF07726.11 ABK75910.1 - 0.0047 16.8 0.1 0.12 12.2 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 ABK75910.1 - 0.0081 16.2 0.0 0.024 14.6 0.0 1.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 ABK75910.1 - 0.011 15.1 0.1 0.017 14.4 0.1 1.2 1 0 0 1 1 1 0 Zeta toxin Rad17 PF03215.15 ABK75910.1 - 0.023 14.6 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain IstB_IS21 PF01695.17 ABK75910.1 - 0.024 14.4 3.3 0.093 12.5 0.2 3.0 2 2 1 3 3 3 0 IstB-like ATP binding protein ResIII PF04851.15 ABK75910.1 - 0.026 14.5 0.0 8.7 6.3 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_14 PF13173.6 ABK75910.1 - 0.028 14.5 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 ABK75910.1 - 0.032 14.1 0.3 0.43 10.5 0.0 2.5 2 1 1 3 3 3 0 NTPase HTH_AsnC-type PF13404.6 ABK75910.1 - 0.032 14.0 0.2 0.19 11.6 0.0 2.3 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain AAA_18 PF13238.6 ABK75910.1 - 0.068 13.7 0.0 0.19 12.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain Resolvase PF00239.21 ABK75910.1 - 0.12 12.5 1.0 0.26 11.4 0.0 2.1 3 1 0 3 3 2 0 Resolvase, N terminal domain AAA_19 PF13245.6 ABK75910.1 - 0.15 12.4 0.5 2.1 8.7 0.1 2.2 1 1 1 2 2 2 0 AAA domain NACHT PF05729.12 ABK75910.1 - 0.15 12.0 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain FAD_binding_2 PF00890.24 ABK75912.1 - 1.5e-89 301.0 0.0 1.7e-89 300.8 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 ABK75912.1 - 2.3e-13 50.3 0.7 1.8e-11 44.1 1.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 ABK75912.1 - 1.5e-08 34.7 2.8 5.4e-07 29.5 0.6 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ABK75912.1 - 5.5e-08 31.9 0.1 9e-08 31.2 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 ABK75912.1 - 7.3e-07 28.7 1.3 8.5e-06 25.2 0.2 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ABK75912.1 - 1.6e-06 28.2 1.6 4.5e-06 26.8 1.6 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ABK75912.1 - 3e-05 23.4 0.4 8.9e-05 21.8 0.3 1.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 ABK75912.1 - 0.00012 21.5 0.0 0.00016 21.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 ABK75912.1 - 0.0011 18.1 2.9 0.0019 17.3 2.9 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 ABK75912.1 - 0.0052 16.1 0.3 0.011 15.0 0.2 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ABK75912.1 - 0.012 16.1 0.3 0.58 10.7 0.5 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ABK75912.1 - 0.024 13.7 0.4 0.039 13.0 0.4 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GDI PF00996.18 ABK75912.1 - 0.054 12.0 0.0 0.096 11.2 0.0 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor Regulator_TrmB PF11495.8 ABK75913.1 - 0.14 11.3 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB adh_short_C2 PF13561.6 ABK75914.1 - 8.1e-19 68.1 0.5 6.7e-17 61.8 0.5 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK75914.1 - 2.1e-14 53.4 0.1 2.8e-14 53.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase F420_oxidored PF03807.17 ABK75914.1 - 0.0002 21.9 0.1 0.00067 20.2 0.1 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 ABK75914.1 - 0.0058 16.1 0.1 0.0077 15.7 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 ABK75914.1 - 0.018 15.3 0.3 2.3 8.5 0.1 2.2 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Glyco_transf_28 PF03033.20 ABK75914.1 - 0.034 14.2 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain RsdA_SigD_bd PF16751.5 ABK75914.1 - 0.037 14.3 1.8 0.068 13.4 0.4 2.2 2 0 0 2 2 2 0 Anti-sigma-D factor RsdA to sigma factor binding region KR PF08659.10 ABK75914.1 - 0.054 13.4 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 KR domain Bac_luciferase PF00296.20 ABK75915.1 - 5.3e-40 137.8 16.6 1.6e-39 136.2 13.4 2.0 1 1 1 2 2 2 2 Luciferase-like monooxygenase HNH_repeat PF18780.1 ABK75915.1 - 0.092 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Homing endonuclease repeat Biotin_lipoyl PF00364.22 ABK75917.1 - 1.9e-16 59.7 5.9 2.5e-16 59.3 5.9 1.2 1 1 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 ABK75917.1 - 3.7e-10 39.5 5.5 1.2e-06 28.2 1.0 2.1 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_D23 PF16576.5 ABK75917.1 - 6.4e-05 22.3 1.5 0.0027 17.0 0.2 2.0 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 ABK75917.1 - 0.00012 22.8 2.2 0.0023 18.6 0.5 2.0 2 0 0 2 2 2 1 HlyD family secretion protein GCV_H PF01597.19 ABK75917.1 - 0.0004 20.3 0.6 0.00045 20.1 0.6 1.2 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 ABK75917.1 - 0.0014 18.6 0.9 0.0044 16.9 0.9 1.8 1 1 0 1 1 1 1 RnfC Barrel sandwich hybrid domain DUF2118 PF09891.9 ABK75917.1 - 0.003 17.5 0.5 0.038 14.0 0.2 1.9 1 1 1 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2118) NQRA PF05896.11 ABK75917.1 - 0.021 14.3 0.2 0.028 13.9 0.2 1.2 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) Glycos_transf_1 PF00534.20 ABK75917.1 - 0.042 13.4 0.4 0.042 13.4 0.4 1.1 1 0 0 1 1 1 0 Glycosyl transferases group 1 QRPTase_N PF02749.16 ABK75917.1 - 0.074 13.1 0.9 4.7 7.4 0.1 2.1 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain Peptidase_M23 PF01551.22 ABK75917.1 - 0.093 12.9 1.6 0.39 10.9 1.6 2.0 1 1 0 1 1 1 0 Peptidase family M23 LMWPc PF01451.21 ABK75919.1 - 1.6e-37 129.0 0.0 1.9e-37 128.8 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Pyridoxal_deC PF00282.19 ABK75920.1 - 2.2e-75 253.7 0.0 3e-75 253.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 ABK75920.1 - 0.0021 17.1 0.0 0.003 16.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DUF1348 PF07080.11 ABK75921.1 - 1.9e-63 212.2 1.6 2.3e-63 211.9 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 ABK75921.1 - 3e-07 31.0 2.5 5.1e-07 30.3 2.3 1.5 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 ABK75921.1 - 0.0012 19.2 0.5 0.0023 18.3 0.4 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) Mn_catalase PF05067.12 ABK75922.1 - 4.7e-68 229.2 0.0 5.9e-68 228.9 0.0 1.1 1 0 0 1 1 1 1 Manganese containing catalase COQ7 PF03232.13 ABK75922.1 - 6e-06 26.1 0.0 0.013 15.3 0.0 2.1 2 0 0 2 2 2 2 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 ABK75922.1 - 0.00028 21.3 0.0 0.04 14.3 0.0 2.2 2 0 0 2 2 2 1 Rubrerythrin Ferritin PF00210.24 ABK75922.1 - 0.0013 18.7 0.2 0.032 14.2 0.1 2.1 2 0 0 2 2 2 1 Ferritin-like domain Ferritin-like PF12902.7 ABK75922.1 - 0.015 15.2 0.0 0.075 12.9 0.0 2.1 3 0 0 3 3 3 0 Ferritin-like Borrelia_REV PF03978.13 ABK75922.1 - 0.22 11.4 0.0 0.33 10.9 0.0 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein MarR_2 PF12802.7 ABK75923.1 - 1.6e-12 47.1 0.4 3.1e-12 46.2 0.4 1.5 1 0 0 1 1 1 1 MarR family MarR PF01047.22 ABK75923.1 - 4.3e-09 36.2 0.0 7.2e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 ABK75923.1 - 2.3e-07 31.2 0.0 3.4e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 ABK75923.1 - 2.5e-06 27.2 0.1 5.3e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_5 PF01022.20 ABK75923.1 - 3.8e-06 26.7 0.0 7.6e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family Fe_dep_repress PF01325.19 ABK75923.1 - 0.00038 20.6 0.0 0.00064 19.9 0.0 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_24 PF13412.6 ABK75923.1 - 0.00082 18.9 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 ABK75923.1 - 0.00083 19.4 0.1 0.0015 18.5 0.1 1.6 1 1 0 1 1 1 1 Helix-turn-helix domain HxlR PF01638.17 ABK75923.1 - 0.0035 17.2 0.0 0.0059 16.4 0.0 1.4 1 0 0 1 1 1 1 HxlR-like helix-turn-helix TrmB PF01978.19 ABK75923.1 - 0.0051 16.7 0.0 0.0093 15.8 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 ABK75923.1 - 0.03 14.7 0.0 0.05 14.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator HTH_Crp_2 PF13545.6 ABK75923.1 - 0.09 12.8 0.0 0.25 11.3 0.0 1.8 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_1 PF00126.27 ABK75923.1 - 0.19 11.7 0.8 0.61 10.1 0.8 1.9 1 1 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Peripla_BP_4 PF13407.6 ABK75924.1 - 1.9e-49 168.6 9.1 2.3e-49 168.3 9.1 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 ABK75924.1 - 7.7e-18 64.9 0.2 9.7e-18 64.6 0.2 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 ABK75924.1 - 1.6e-06 28.5 0.0 5.4e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Bmp PF02608.14 ABK75924.1 - 1.3e-05 24.4 1.1 0.087 11.8 0.1 2.3 2 1 0 2 2 2 2 ABC transporter substrate-binding protein PnrA-like Nitro_FeMo-Co PF02579.17 ABK75924.1 - 0.041 14.2 0.2 1.9 8.9 0.0 2.5 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor B12-binding PF02310.19 ABK75924.1 - 0.075 13.1 0.1 0.33 11.0 0.1 2.1 1 1 0 1 1 1 0 B12 binding domain FAD_binding_3 PF01494.19 ABK75925.1 - 5.2e-69 233.1 2.2 6e-69 232.9 2.2 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ABK75925.1 - 7.2e-11 42.3 8.2 1.3e-06 28.3 1.5 2.8 1 1 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ABK75925.1 - 4.8e-09 35.8 0.8 4.8e-09 35.8 0.8 2.3 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 ABK75925.1 - 7e-09 35.3 0.2 0.00015 21.1 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ABK75925.1 - 1.4e-06 27.3 1.6 0.00032 19.5 0.9 2.4 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox PF00070.27 ABK75925.1 - 2e-06 28.2 0.7 0.0016 19.0 0.4 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ABK75925.1 - 2.2e-06 27.2 0.5 0.00068 19.0 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ABK75925.1 - 4.1e-06 26.9 0.6 4.1e-05 23.7 0.4 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ABK75925.1 - 0.00011 21.5 1.7 0.00045 19.5 1.0 2.2 2 1 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 ABK75925.1 - 0.00017 20.8 3.4 0.00017 20.8 3.4 1.9 2 1 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 ABK75925.1 - 0.0005 19.5 2.7 0.00083 18.8 2.7 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 ABK75925.1 - 0.00065 18.7 1.0 0.62 8.9 0.7 2.1 2 0 0 2 2 2 2 Tryptophan halogenase XdhC_C PF13478.6 ABK75925.1 - 0.00067 20.2 0.1 0.0037 17.8 0.0 2.3 3 1 0 3 3 2 1 XdhC Rossmann domain NAD_binding_7 PF13241.6 ABK75925.1 - 0.00099 19.5 0.3 0.005 17.2 0.1 2.1 2 1 1 3 3 2 1 Putative NAD(P)-binding NAD_binding_9 PF13454.6 ABK75925.1 - 0.0011 19.0 1.7 1.3 9.0 0.3 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 ABK75925.1 - 0.0018 17.9 0.1 0.0034 17.0 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Amino_oxidase PF01593.24 ABK75925.1 - 0.004 16.5 0.4 1.1 8.4 0.2 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase 3HCDH_N PF02737.18 ABK75925.1 - 0.0041 17.0 0.3 0.0073 16.2 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 ABK75925.1 - 0.0044 17.3 0.1 0.011 15.9 0.1 1.7 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.21 ABK75925.1 - 0.0066 15.8 2.6 0.011 15.1 2.5 1.5 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain SE PF08491.10 ABK75925.1 - 0.011 14.8 0.0 0.02 14.0 0.0 1.4 2 0 0 2 2 2 0 Squalene epoxidase ApbA PF02558.16 ABK75925.1 - 0.014 15.0 0.3 0.027 14.1 0.3 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glu_dehyd_C PF16912.5 ABK75925.1 - 0.021 14.3 0.1 0.043 13.3 0.1 1.6 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus MBT PF02820.18 ABK75925.1 - 0.037 14.4 0.0 4.8 7.6 0.0 2.4 2 0 0 2 2 2 0 mbt repeat GIDA PF01134.22 ABK75925.1 - 0.44 9.6 3.0 0.76 8.8 1.6 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A LigB PF02900.18 ABK75926.1 - 3e-29 101.9 0.0 3.4e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase FMN_red PF03358.15 ABK75927.1 - 1.3e-16 60.8 0.0 1.7e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 ABK75927.1 - 1.4e-09 37.9 0.0 2.1e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.7 ABK75927.1 - 1.1e-08 35.4 0.1 0.00032 21.0 0.0 2.5 3 0 0 3 3 3 2 Flavodoxin domain Flavodoxin_1 PF00258.25 ABK75927.1 - 0.00012 22.3 0.2 0.00041 20.6 0.2 1.7 1 1 0 1 1 1 1 Flavodoxin GDC-P PF02347.16 ABK75927.1 - 0.07 11.9 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 Glycine cleavage system P-protein Cas_APE2256 PF09651.10 ABK75927.1 - 0.15 12.0 0.0 4.4 7.2 0.0 2.1 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_APE2256) Molybdopterin PF00384.22 ABK75929.1 - 4.3e-26 91.8 0.0 6.8e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 ABK75929.1 - 2.9e-08 33.7 0.0 6.5e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain WXG100 PF06013.12 ABK75930.1 - 6.7e-15 55.1 6.6 7.8e-15 54.9 6.6 1.1 1 0 0 1 1 1 1 Proteins of 100 residues with WXG T7SS_ESX_EspC PF10824.8 ABK75930.1 - 6e-05 23.5 10.9 6.7e-05 23.3 10.9 1.1 1 0 0 1 1 1 1 Excreted virulence factor EspC, type VII ESX diderm Spc7 PF08317.11 ABK75930.1 - 0.0021 17.0 0.1 0.0023 16.9 0.1 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein H-kinase_dim PF02895.14 ABK75930.1 - 0.015 15.6 0.3 1.4 9.4 0.0 2.2 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain G2F PF07474.12 ABK75930.1 - 0.023 14.5 0.0 0.029 14.2 0.0 1.2 1 0 0 1 1 1 0 G2F domain PE PF00934.20 ABK75930.1 - 0.99 9.8 12.4 1.5 9.2 12.4 1.4 1 1 0 1 1 1 0 PE family Fe_dep_repr_C PF02742.15 ABK75931.1 - 3.2e-31 107.2 0.1 1.6e-30 105.0 0.1 2.0 2 0 0 2 2 2 1 Iron dependent repressor, metal binding and dimerisation domain FeoA PF04023.14 ABK75931.1 - 7.7e-22 77.4 0.0 1.8e-21 76.1 0.0 1.7 2 0 0 2 2 1 1 FeoA domain Fe_dep_repress PF01325.19 ABK75931.1 - 7.8e-22 77.2 0.1 1.3e-21 76.5 0.1 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_27 PF13463.6 ABK75931.1 - 8.9e-06 26.1 0.1 1.8e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_24 PF13412.6 ABK75931.1 - 4.5e-05 22.9 0.1 8.5e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 ABK75931.1 - 5.6e-05 23.0 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_20 PF12840.7 ABK75931.1 - 0.00016 21.6 0.1 0.00051 20.1 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 ABK75931.1 - 0.0002 21.2 0.2 0.00042 20.2 0.2 1.6 1 0 0 1 1 1 1 MarR family GntR PF00392.21 ABK75931.1 - 0.00027 20.5 0.0 0.00065 19.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family MarR PF01047.22 ABK75931.1 - 0.00032 20.6 0.1 0.00062 19.6 0.1 1.5 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 ABK75931.1 - 0.00051 19.9 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_10 PF04967.12 ABK75931.1 - 0.0026 17.5 0.1 0.0056 16.5 0.1 1.6 1 0 0 1 1 1 1 HTH DNA binding domain HTH_5 PF01022.20 ABK75931.1 - 0.0027 17.5 0.1 0.0049 16.7 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_DeoR PF08220.12 ABK75931.1 - 0.0039 16.9 0.4 0.0099 15.6 0.0 1.9 2 0 0 2 2 1 1 DeoR-like helix-turn-helix domain Rrf2 PF02082.20 ABK75931.1 - 0.0039 17.5 0.1 0.0073 16.6 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulator Penicillinase_R PF03965.16 ABK75931.1 - 0.0063 16.8 0.2 0.0095 16.3 0.2 1.3 1 0 0 1 1 1 1 Penicillinase repressor HTH_36 PF13730.6 ABK75931.1 - 0.011 15.6 0.1 0.019 14.9 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.12 ABK75931.1 - 0.012 15.6 0.1 0.023 14.6 0.1 1.4 1 0 0 1 1 1 0 HTH domain HTH_1 PF00126.27 ABK75931.1 - 0.03 14.3 0.1 0.13 12.2 0.1 2.1 1 1 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_IclR PF09339.10 ABK75931.1 - 0.033 14.0 1.6 0.097 12.5 0.1 2.2 1 1 1 2 2 2 0 IclR helix-turn-helix domain MerR PF00376.23 ABK75931.1 - 0.041 13.6 0.2 8.5 6.2 0.0 3.3 3 1 0 3 3 3 0 MerR family regulatory protein Ribosomal_S25 PF03297.15 ABK75931.1 - 0.043 14.0 0.0 0.08 13.2 0.0 1.4 1 0 0 1 1 1 0 S25 ribosomal protein HTH_AsnC-type PF13404.6 ABK75931.1 - 0.082 12.8 0.2 0.082 12.8 0.2 2.2 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Rio2_N PF09202.11 ABK75931.1 - 0.092 13.0 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Rio2, N-terminal DUF2250 PF10007.9 ABK75931.1 - 0.092 12.9 0.1 0.22 11.7 0.1 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) DUF4423 PF14394.6 ABK75931.1 - 0.17 11.6 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) Peripla_BP_4 PF13407.6 ABK75932.1 - 2.2e-60 204.4 12.3 2.8e-60 204.1 12.3 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 ABK75932.1 - 9.9e-15 54.7 0.3 1.4e-14 54.2 0.3 1.2 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 ABK75932.1 - 3.3e-05 24.3 0.0 0.00012 22.4 0.0 1.9 1 1 1 2 2 2 1 Periplasmic binding protein-like domain MFS_1 PF07690.16 ABK75933.1 - 1.7e-38 132.5 76.5 1.1e-27 96.9 38.1 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF2070 PF09843.9 ABK75933.1 - 0.46 8.7 17.3 0.017 13.4 0.6 2.6 1 1 0 2 2 2 0 Predicted membrane protein (DUF2070) Pyridox_ox_2 PF12900.7 ABK75934.1 - 5.6e-24 84.7 0.1 6.5e-24 84.5 0.1 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 ABK75934.1 - 0.054 13.7 0.0 0.48 10.7 0.0 2.2 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase GARS_A PF01071.19 ABK75935.1 - 3.8e-66 222.6 0.0 5.1e-66 222.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_C PF02843.16 ABK75935.1 - 5.1e-25 87.6 0.6 1.5e-24 86.0 0.6 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain GARS_N PF02844.15 ABK75935.1 - 1.2e-16 61.3 0.1 2.7e-16 60.1 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain ATP-grasp_3 PF02655.14 ABK75935.1 - 0.00028 21.0 0.0 0.00069 19.7 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain SSP160 PF06933.11 ABK75936.1 - 9.8 4.2 10.9 10 4.2 10.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 adh_short PF00106.25 ABK75937.1 - 6.3e-49 166.1 0.0 8.6e-49 165.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK75937.1 - 1.8e-35 122.6 0.1 2.4e-35 122.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK75937.1 - 1.8e-06 28.0 0.2 9.7e-06 25.6 0.2 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK75937.1 - 0.0013 18.3 0.2 0.0022 17.5 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Hemerythrin PF01814.23 ABK75938.1 - 1.1e-06 29.3 8.9 1.2e-06 29.1 8.9 1.0 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain PMP22_Claudin PF00822.20 ABK75939.1 - 0.028 14.3 0.5 0.034 14.0 0.5 1.0 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF2273 PF10031.9 ABK75939.1 - 0.19 11.7 0.9 0.19 11.7 0.9 2.2 2 0 0 2 2 2 0 Small integral membrane protein (DUF2273) DUF3040 PF11239.8 ABK75939.1 - 8.4 6.8 10.7 93 3.4 10.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) CoA_transf_3 PF02515.17 ABK75940.1 - 5e-85 285.8 0.1 6.2e-85 285.5 0.1 1.1 1 0 0 1 1 1 1 CoA-transferase family III MS_channel PF00924.18 ABK75941.1 - 5e-40 137.3 0.8 8.1e-40 136.6 0.8 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel FtsX PF02687.21 ABK75941.1 - 0.17 12.4 4.0 1.5 9.4 0.5 2.4 1 1 1 2 2 2 0 FtsX-like permease family Rieske PF00355.26 ABK75942.1 - 2.4e-09 37.0 0.0 4e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain SDF PF00375.18 ABK75943.1 - 4e-99 332.3 39.3 4.5e-99 332.1 39.3 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family CwsA PF10814.8 ABK75943.1 - 0.046 13.9 0.0 0.16 12.2 0.0 1.9 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA YtxH PF12732.7 ABK75943.1 - 2.2 8.9 4.9 22 5.7 1.2 2.7 2 0 0 2 2 2 0 YtxH-like protein Glyoxalase PF00903.25 ABK75944.1 - 2.6e-09 37.3 0.0 3.1e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 ABK75944.1 - 0.00047 20.1 0.0 0.00079 19.3 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain PP2C_2 PF13672.6 ABK75945.1 - 1.3e-09 38.0 0.3 1.9e-09 37.5 0.3 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 ABK75945.1 - 6.5e-09 36.0 2.2 1.8e-07 31.3 2.2 2.1 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) ADH_N PF08240.12 ABK75946.1 - 4e-33 113.5 0.5 6.5e-33 112.9 0.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ABK75946.1 - 5.2e-09 36.2 0.1 1.9e-08 34.3 0.1 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ABK75946.1 - 0.00098 20.2 0.1 0.0029 18.7 0.0 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase DctM PF06808.12 ABK75946.1 - 0.092 11.6 0.1 0.12 11.2 0.1 1.1 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporter, DctM component Peptidase_M19 PF01244.21 ABK75947.1 - 8.3e-112 373.5 0.0 9.4e-112 373.3 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) FMO-like PF00743.19 ABK75948.1 - 5.9e-16 58.0 0.0 1.3e-13 50.2 0.0 2.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ABK75948.1 - 8.7e-13 48.2 0.0 5.1e-12 45.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ABK75948.1 - 1.9e-10 40.9 2.5 4.1e-07 29.9 0.1 3.5 3 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ABK75948.1 - 1.5e-09 37.5 0.0 1.1e-07 31.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ABK75948.1 - 4.9e-09 36.3 0.1 1.4e-07 31.6 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 ABK75948.1 - 1.7e-08 34.0 0.0 7.3e-05 22.1 0.0 2.7 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 ABK75948.1 - 4.5e-06 26.1 0.0 5.1e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Shikimate_DH PF01488.20 ABK75948.1 - 6.5e-06 26.3 0.0 0.0021 18.1 0.0 3.0 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 ABK75948.1 - 0.0012 19.4 0.0 1 10.0 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 ABK75948.1 - 0.0037 15.9 0.1 1.7 7.1 0.0 3.1 3 0 0 3 3 3 1 Malate:quinone oxidoreductase (Mqo) FAD_binding_3 PF01494.19 ABK75948.1 - 0.004 16.5 0.0 1.8 7.7 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.6 ABK75948.1 - 0.0046 16.9 3.4 0.28 11.2 0.0 3.8 3 1 1 4 4 4 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 ABK75948.1 - 0.029 13.6 0.0 0.06 12.6 0.0 1.5 1 1 0 1 1 1 0 Flavin containing amine oxidoreductase GIDA PF01134.22 ABK75948.1 - 0.072 12.2 0.4 3 6.8 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 ABK75948.1 - 0.074 13.5 0.0 0.3 11.5 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 ABK75948.1 - 0.13 11.2 0.7 1.7 7.6 0.0 2.8 3 1 0 3 3 3 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 ABK75948.1 - 0.17 10.9 0.0 0.39 9.7 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain Aminotran_3 PF00202.21 ABK75949.1 - 1.6e-97 326.8 0.0 1.9e-97 326.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III BPD_transp_1 PF00528.22 ABK75950.1 - 8.7e-17 61.5 16.7 8.7e-17 61.5 16.7 1.4 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Response_reg PF00072.24 ABK75951.1 - 7.2e-21 74.5 0.1 1e-20 73.9 0.1 1.2 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 ABK75951.1 - 2e-20 72.1 0.1 3.3e-20 71.4 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family TadZ_N PF16968.5 ABK75951.1 - 0.00037 20.2 1.6 0.00064 19.4 1.6 1.5 1 0 0 1 1 1 1 Pilus assembly protein TadZ N-terminal HTH_10 PF04967.12 ABK75951.1 - 0.024 14.4 0.2 1.1 9.1 0.2 2.6 1 1 0 1 1 1 0 HTH DNA binding domain HTH_23 PF13384.6 ABK75951.1 - 0.039 13.8 0.0 0.96 9.3 0.0 2.5 1 1 1 2 2 2 0 Homeodomain-like domain HTH_24 PF13412.6 ABK75951.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF21 PF01595.20 ABK75952.1 - 4.6e-37 127.4 2.4 6.2e-37 127.0 2.4 1.1 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 ABK75952.1 - 1.6e-21 76.1 0.1 3.6e-21 74.9 0.1 1.6 1 0 0 1 1 1 1 Transporter associated domain CBS PF00571.28 ABK75952.1 - 5.7e-12 45.9 1.2 1.7e-05 25.2 0.2 2.5 2 0 0 2 2 2 2 CBS domain DUF4229 PF14012.6 ABK75952.1 - 0.97 9.6 5.3 1.6 8.9 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) YibE_F PF07907.11 ABK75953.1 - 1.6e-65 220.9 25.0 1.6e-65 220.9 25.0 1.5 2 0 0 2 2 2 1 YibE/F-like protein DUF2613 PF11021.8 ABK75953.1 - 0.027 14.6 1.8 0.027 14.6 1.8 5.2 6 0 0 6 6 6 0 Protein of unknown function (DUF2613) ATP-synt_Eps PF04627.13 ABK75954.1 - 0.031 14.3 0.3 0.035 14.1 0.3 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase epsilon chain MFS_1 PF07690.16 ABK75956.1 - 4.9e-43 147.4 136.0 5.9e-23 81.4 47.5 3.8 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK75956.1 - 0.0028 16.6 15.2 0.0028 16.6 15.2 3.8 4 0 0 4 4 4 3 Sugar (and other) transporter LigD_N PF13298.6 ABK75957.1 - 4.8e-37 126.4 0.0 9.7e-37 125.5 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase Ligase (LigD) DNA_ligase_A_M PF01068.21 ABK75957.1 - 2.5e-31 108.9 0.0 5.3e-31 107.9 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 ABK75957.1 - 9.7e-24 83.9 0.1 3.6e-23 82.0 0.0 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 ABK75957.1 - 3.4e-06 27.4 0.0 7.1e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 RNA ligase Thr_synth_N PF14821.6 ABK75957.1 - 0.0019 18.4 0.0 0.007 16.6 0.0 1.9 1 0 0 1 1 1 1 Threonine synthase N terminus DNA_primase_S PF01896.19 ABK75957.1 - 0.1 12.6 0.0 1.3 9.0 0.0 2.6 2 1 0 2 2 2 0 DNA primase small subunit PhoH PF02562.16 ABK75958.1 - 2.1e-52 177.6 0.0 2.7e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 PhoH-like protein PIN_4 PF13638.6 ABK75958.1 - 3.7e-28 98.4 0.0 5.8e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 PIN domain AAA_30 PF13604.6 ABK75958.1 - 1.1e-07 31.8 0.1 2.1e-07 30.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ABK75958.1 - 0.015 15.7 1.0 0.03 14.7 1.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 ABK75958.1 - 0.03 14.6 1.2 0.23 11.7 1.2 2.2 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 ABK75958.1 - 0.056 13.2 0.0 0.62 9.8 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase Histone PF00125.24 ABK75958.1 - 0.2 12.0 0.0 0.33 11.3 0.0 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 PEP_mutase PF13714.6 ABK75959.1 - 2.9e-49 167.7 4.2 3.4e-49 167.5 4.2 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 ABK75959.1 - 7e-12 44.6 0.3 1e-11 44.1 0.3 1.2 1 0 0 1 1 1 1 Isocitrate lyase family DUF4333 PF14230.6 ABK75960.1 - 6.7e-26 90.3 2.3 1e-25 89.7 2.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4333) Collagen PF01391.18 ABK75960.1 - 0.00013 21.6 31.3 0.00013 21.6 31.3 3.2 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) Glucodextran_B PF09136.10 ABK75960.1 - 0.12 12.8 0.3 0.18 12.2 0.3 1.3 1 0 0 1 1 1 0 Glucodextranase, domain B HTH_30 PF13556.6 ABK75961.1 - 1.2e-16 60.2 1.2 1.2e-16 60.2 1.2 2.0 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain GGDEF_2 PF17853.1 ABK75961.1 - 9.8e-06 25.8 4.3 9.8e-06 25.8 4.3 3.7 4 0 0 4 4 4 1 GGDEF-like domain HTH_8 PF02954.19 ABK75961.1 - 1.1e-05 25.1 0.0 5.3e-05 22.9 0.0 2.3 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family HTH_18 PF12833.7 ABK75962.1 - 3.7e-17 62.4 2.1 3.7e-17 62.4 2.1 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 ABK75962.1 - 4e-11 42.7 0.0 8.7e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family YjgF_endoribonc PF14588.6 ABK75963.1 - 7.9e-22 78.0 0.0 8.9e-22 77.8 0.0 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 ABK75963.1 - 2.1e-10 40.7 0.0 2.6e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP FCD PF07729.12 ABK75964.1 - 1.7e-17 64.0 7.0 3.4e-17 63.0 7.0 1.4 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 ABK75964.1 - 4.6e-15 55.0 1.6 9.5e-15 54.0 0.6 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family TFIIE_alpha PF02002.17 ABK75964.1 - 0.0018 18.1 0.0 0.0039 17.0 0.0 1.5 1 1 0 1 1 1 1 TFIIE alpha subunit ADSL_C PF10397.9 ABK75964.1 - 0.0083 16.6 1.2 0.066 13.8 1.2 2.4 1 1 0 1 1 1 1 Adenylosuccinate lyase C-terminus UDPG_MGDP_dh_C PF03720.15 ABK75964.1 - 0.03 14.8 0.0 0.05 14.0 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain CbiJ PF02571.14 ABK75964.1 - 0.045 13.2 0.1 0.076 12.5 0.1 1.3 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK Phage_rep_O PF04492.13 ABK75964.1 - 0.19 12.3 0.0 0.54 10.9 0.0 1.8 1 1 0 1 1 1 0 Bacteriophage replication protein O DUF417 PF04224.12 ABK75965.1 - 2e-34 118.7 4.7 1.3e-32 112.7 4.7 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF417 Sec62 PF03839.16 ABK75965.1 - 0.47 9.9 1.4 0.62 9.5 1.4 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Lactamase_B PF00753.27 ABK75967.1 - 1.2e-15 58.1 11.9 5.5e-15 55.9 11.9 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 ABK75967.1 - 3.2e-07 30.2 0.1 6.7e-07 29.2 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 ABK75967.1 - 1.6e-06 27.8 1.4 7.3e-06 25.6 1.4 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ABK75967.1 - 0.00028 20.8 0.0 0.00036 20.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF4777 PF16007.5 ABK75967.1 - 0.12 12.7 0.0 0.3 11.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) HIT PF01230.23 ABK75969.1 - 2.3e-15 57.1 0.0 3.4e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 ABK75969.1 - 1.6e-07 31.8 0.0 2.7e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 ABK75969.1 - 0.00014 21.7 0.0 0.00023 21.0 0.0 1.4 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 GalP_UDP_tr_C PF02744.17 ABK75969.1 - 0.094 12.4 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain LysE PF01810.18 ABK75970.1 - 1.2e-25 90.1 11.4 1.5e-25 89.8 11.4 1.1 1 0 0 1 1 1 1 LysE type translocator Oxidored_q4 PF00507.19 ABK75970.1 - 0.43 10.8 2.1 1.7 8.9 0.1 2.2 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 MLTR_LBD PF17765.1 ABK75971.1 - 1.2e-35 123.2 1.1 1.6e-35 122.7 1.1 1.2 1 0 0 1 1 1 1 MmyB-like transcription regulator ligand binding domain HTH_31 PF13560.6 ABK75971.1 - 3e-17 62.7 3.3 1.3e-16 60.7 3.3 2.1 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 ABK75971.1 - 2.1e-07 30.9 0.0 3.7e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix PhoD PF09423.10 ABK75974.1 - 8.7e-78 261.8 0.0 1e-77 261.5 0.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 ABK75974.1 - 2e-21 76.3 0.0 4.1e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 ABK75974.1 - 0.011 16.3 0.0 0.027 15.0 0.0 1.7 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain CarboxypepD_reg PF13620.6 ABK75974.1 - 0.094 13.0 0.9 1.5 9.2 0.1 2.5 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain TAT_signal PF10518.9 ABK75974.1 - 0.14 12.0 2.4 0.29 11.0 2.4 1.5 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence adh_short PF00106.25 ABK75975.1 - 2.2e-34 118.6 0.4 3.1e-34 118.2 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK75975.1 - 3.2e-27 95.6 0.9 4e-27 95.3 0.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ABK75975.1 - 7.8e-07 28.8 0.4 1.1e-06 28.3 0.4 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ABK75975.1 - 4.3e-06 26.7 0.4 8e-06 25.9 0.4 1.4 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 ABK75975.1 - 9.1e-06 25.0 0.2 1.7e-05 24.1 0.2 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 ABK75975.1 - 7.4e-05 22.7 2.7 0.00052 20.0 2.7 2.0 1 1 0 1 1 1 1 KR domain DFP PF04127.15 ABK75975.1 - 0.0062 16.4 0.2 0.011 15.5 0.2 1.4 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein 3Beta_HSD PF01073.19 ABK75975.1 - 0.073 12.1 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ABK75975.1 - 0.12 11.7 0.1 0.27 10.6 0.1 1.6 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF5518 PF17647.1 ABK75976.1 - 0.017 15.2 3.8 0.017 15.2 3.8 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5518) K_trans PF02705.16 ABK75976.1 - 0.026 13.1 0.5 0.03 12.9 0.5 1.1 1 0 0 1 1 1 0 K+ potassium transporter Adeno_E3_CR2 PF02439.15 ABK75976.1 - 0.049 13.4 2.7 0.049 13.4 2.7 2.3 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 DUF998 PF06197.13 ABK75976.1 - 0.11 12.1 14.0 0.12 12.0 14.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) DUF3357 PF11837.8 ABK75976.1 - 1.3 9.5 3.9 13 6.3 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Na_H_Exchanger PF00999.21 ABK75977.1 - 6.1e-51 173.4 39.5 7.7e-51 173.1 39.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Alkyl_sulf_dimr PF14863.6 ABK75977.1 - 0.085 13.3 1.3 0.15 12.5 1.3 1.3 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation DUF2919 PF11143.8 ABK75977.1 - 0.2 12.0 1.5 0.65 10.3 1.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2919) CCB1 PF12046.8 ABK75977.1 - 1.7 8.0 4.7 6.7 6.0 0.6 2.9 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B MLANA PF14991.6 ABK75977.1 - 2.6 8.4 3.5 1.3 9.3 0.3 2.2 2 0 0 2 2 2 0 Protein melan-A Thiolase_N PF00108.23 ABK75978.1 - 7.5e-12 45.2 0.3 3.7e-10 39.6 0.3 2.2 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ABK75978.1 - 9.6e-11 41.4 0.1 2.2e-09 37.0 0.0 2.3 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ABK75978.1 - 1.7e-05 24.6 0.6 6.8e-05 22.6 0.9 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Dodecin PF07311.12 ABK75978.1 - 0.013 15.7 0.0 0.071 13.4 0.0 2.2 2 0 0 2 2 2 0 Dodecin ACP_syn_III PF08545.10 ABK75978.1 - 0.035 13.9 0.8 0.34 10.8 0.2 2.6 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III AMP-binding PF00501.28 ABK75979.1 - 2.8e-77 260.1 0.0 3.5e-77 259.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK75979.1 - 2.3e-20 73.4 0.4 6.9e-20 71.8 0.1 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain BPD_transp_2 PF02653.16 ABK75980.1 - 1.1e-50 172.3 38.7 1.2e-50 172.1 38.7 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component DUF2304 PF10066.9 ABK75980.1 - 0.84 9.9 0.0 0.84 9.9 0.0 3.4 3 2 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) Methyltransf_11 PF08241.12 ABK75981.1 - 3.6e-21 75.6 0.0 6.4e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ABK75981.1 - 3.4e-17 62.9 0.0 1e-16 61.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK75981.1 - 2.7e-09 37.7 0.0 6.4e-09 36.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABK75981.1 - 1.3e-07 31.6 0.0 3.6e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ABK75981.1 - 2e-06 27.3 0.0 3.1e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 ABK75981.1 - 5e-06 26.4 0.0 6.9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 ABK75981.1 - 0.002 18.0 0.0 0.004 17.0 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 ABK75981.1 - 0.016 14.8 0.0 0.5 9.9 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain RrnaAD PF00398.20 ABK75981.1 - 0.016 14.3 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_29 PF03141.16 ABK75981.1 - 0.024 13.2 0.0 0.03 12.9 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase IstB_IS21 PF01695.17 ABK75982.1 - 9.6e-55 185.1 0.0 1.4e-54 184.5 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_30 PF13604.6 ABK75982.1 - 1.8e-07 31.1 0.1 2.4e-06 27.4 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA PF00004.29 ABK75982.1 - 5.7e-05 23.5 0.0 0.00014 22.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ABK75982.1 - 0.00028 21.2 0.2 0.028 14.7 0.1 3.1 2 2 1 3 3 3 1 AAA domain AAA_5 PF07728.14 ABK75982.1 - 0.00034 20.6 0.0 0.00069 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.23 ABK75982.1 - 0.0022 17.1 0.0 0.0033 16.6 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain AAA_33 PF13671.6 ABK75982.1 - 0.0033 17.6 2.5 0.011 15.9 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 ABK75982.1 - 0.0041 16.7 2.2 0.023 14.3 0.2 2.6 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 ABK75982.1 - 0.0061 17.1 0.0 0.012 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ABK75982.1 - 0.0069 16.7 0.9 0.021 15.2 0.3 2.2 1 1 1 2 2 2 1 AAA domain AAA_11 PF13086.6 ABK75982.1 - 0.0069 16.2 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 ABK75982.1 - 0.0079 15.4 0.0 0.051 12.8 0.0 1.9 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_16 PF13191.6 ABK75982.1 - 0.008 16.6 4.9 0.0092 16.4 0.1 2.8 1 1 2 3 3 3 1 AAA ATPase domain AAA_28 PF13521.6 ABK75982.1 - 0.012 15.9 0.8 0.028 14.6 0.1 2.0 2 1 0 2 2 2 0 AAA domain CbiA PF01656.23 ABK75982.1 - 0.013 15.5 0.1 0.027 14.5 0.1 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain TACC_C PF05010.14 ABK75982.1 - 0.023 14.5 0.4 0.035 13.9 0.4 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal AAA_7 PF12775.7 ABK75982.1 - 0.026 14.1 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RuvB_N PF05496.12 ABK75982.1 - 0.03 14.1 0.0 0.052 13.3 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 ABK75982.1 - 0.032 14.2 0.1 0.37 10.7 0.0 2.2 1 1 1 2 2 2 0 NACHT domain PhoH PF02562.16 ABK75982.1 - 0.042 13.3 0.1 0.08 12.4 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 ABK75982.1 - 0.045 13.1 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 KaiC TsaE PF02367.17 ABK75982.1 - 0.046 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 ABK75982.1 - 0.052 13.4 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_24 PF13479.6 ABK75982.1 - 0.055 13.2 0.0 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ABK75982.1 - 0.056 13.8 0.0 0.15 12.5 0.0 1.7 1 1 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 ABK75982.1 - 0.068 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI 6PF2K PF01591.18 ABK75982.1 - 0.08 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase hemP PF10636.9 ABK75982.1 - 0.087 12.6 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 Hemin uptake protein hemP AAA_3 PF07726.11 ABK75982.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 ABK75982.1 - 0.15 12.0 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SRP54 PF00448.22 ABK75982.1 - 0.16 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 ABK75982.1 - 0.19 11.6 0.0 7 6.5 0.0 2.4 1 1 1 2 2 2 0 NTPase GTP-bdg_N PF13167.6 ABK75983.1 - 1.7e-33 115.1 0.0 3.6e-33 114.1 0.0 1.6 1 0 0 1 1 1 1 GTP-binding GTPase N-terminal GTP-bdg_M PF16360.5 ABK75983.1 - 3.9e-30 104.3 11.0 4.5e-30 104.1 7.0 2.7 3 1 1 4 4 4 1 GTP-binding GTPase Middle Region MMR_HSR1 PF01926.23 ABK75983.1 - 1.7e-21 76.4 0.0 3.4e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ABK75983.1 - 8.6e-07 28.6 0.0 2.4e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 ABK75983.1 - 1.5e-05 25.1 0.0 3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Dynamin family DAO PF01266.24 ABK75983.1 - 4.5e-05 23.2 0.4 7.3e-05 22.5 0.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase MMR_HSR1_Xtn PF16897.5 ABK75983.1 - 0.00018 21.5 0.0 0.00058 19.9 0.0 1.8 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Arf PF00025.21 ABK75983.1 - 0.003 17.0 0.0 0.18 11.2 0.0 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 ABK75983.1 - 0.0055 16.6 0.0 0.38 10.6 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 ABK75983.1 - 0.0062 16.9 0.5 0.026 14.9 0.0 2.2 1 1 2 3 3 3 1 AAA ATPase domain cobW PF02492.19 ABK75983.1 - 0.014 14.9 3.8 0.27 10.8 0.1 3.2 2 2 2 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 ABK75983.1 - 0.024 14.1 0.0 0.042 13.3 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_23 PF13476.6 ABK75983.1 - 0.063 13.8 0.9 0.12 12.8 0.2 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ABK75983.1 - 0.063 13.8 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter ATP-grasp PF02222.22 ABK75984.1 - 8.3e-52 175.2 0.0 2e-51 174.0 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 ABK75984.1 - 6.1e-08 32.4 0.0 4.5e-07 29.6 0.0 2.2 2 1 0 2 2 2 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 ABK75984.1 - 3.9e-05 23.2 0.0 5.1e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 ABK75984.1 - 0.00012 22.2 0.0 0.0005 20.2 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain Epimerase PF01370.21 ABK75984.1 - 0.00071 19.1 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 ABK75984.1 - 0.0042 16.5 0.0 0.0079 15.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GARS_A PF01071.19 ABK75984.1 - 0.0053 16.5 0.0 0.0091 15.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RmlD_sub_bind PF04321.17 ABK75984.1 - 0.013 14.6 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain ThiF PF00899.21 ABK75984.1 - 0.026 13.9 0.1 0.05 13.0 0.1 1.4 1 0 0 1 1 1 0 ThiF family ATP-grasp_4 PF13535.6 ABK75984.1 - 0.038 13.6 0.0 0.1 12.2 0.0 1.8 1 0 0 1 1 1 0 ATP-grasp domain Oxidored_nitro PF00148.19 ABK75984.1 - 0.072 11.8 0.1 0.12 11.1 0.1 1.3 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase GARS_N PF02844.15 ABK75984.1 - 0.12 13.2 0.1 0.31 11.9 0.1 1.7 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain PurS PF02700.14 ABK75985.1 - 2.2e-25 88.6 0.0 2.5e-25 88.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoribosylformylglycinamidine (FGAM) synthase NitrOD2 PF18550.1 ABK75985.1 - 0.068 13.3 0.0 0.08 13.1 0.0 1.2 1 0 0 1 1 1 0 Nitrososphaera output domain 2 Abhydrolase_6 PF12697.7 ABK75986.1 - 4e-20 73.4 6.0 4.7e-20 73.1 6.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ABK75986.1 - 9.6e-11 41.8 0.2 2.2e-09 37.3 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 ABK75986.1 - 3.1e-06 27.2 0.0 9.9e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 TAP-like protein Hydrolase_4 PF12146.8 ABK75986.1 - 0.0035 16.6 1.5 0.49 9.6 0.0 2.4 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Ribonuc_L-PSP PF01042.21 ABK75987.1 - 6e-24 84.4 0.1 7.4e-24 84.1 0.1 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Mgm101p PF06420.12 ABK75987.1 - 0.091 12.3 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial genome maintenance MGM101 Bac_luciferase PF00296.20 ABK75988.1 - 1.3e-54 185.8 3.0 1.8e-54 185.3 3.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF1727 PF08353.10 ABK75989.1 - 2.3e-23 82.2 0.0 6e-23 80.9 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1727) Mur_ligase_M PF08245.12 ABK75989.1 - 1.6e-15 57.6 0.0 3.6e-15 56.5 0.0 1.6 1 1 0 1 1 1 1 Mur ligase middle domain 3HCDH_N PF02737.18 ABK75990.1 - 3.4e-64 216.0 0.9 2e-63 213.6 0.2 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 ABK75990.1 - 1e-34 120.0 1.7 1.8e-34 119.2 0.8 1.8 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 ABK75990.1 - 1.6e-19 70.3 0.4 2.4e-18 66.5 0.0 2.8 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 ABK75990.1 - 1.3e-18 67.6 0.3 2.8e-18 66.5 0.3 1.5 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase NAD_binding_2 PF03446.15 ABK75990.1 - 0.0073 16.5 2.9 0.0085 16.3 0.9 2.2 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ABK75990.1 - 0.017 15.7 0.2 0.056 14.0 0.2 2.0 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 ABK75990.1 - 0.03 13.6 0.8 0.058 12.7 0.8 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ABK75990.1 - 0.12 11.8 0.1 0.24 10.7 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 ABK75990.1 - 0.14 12.4 0.3 0.36 11.1 0.3 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NTP_transferase PF00483.23 ABK75991.1 - 2.3e-71 240.3 0.0 3.1e-71 239.9 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 ABK75991.1 - 2.2e-06 28.1 0.0 3.4e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 ABK75991.1 - 0.00023 20.2 0.0 0.00042 19.4 0.0 1.4 1 0 0 1 1 1 1 L-fucokinase Hexapep PF00132.24 ABK75991.1 - 0.001 18.7 8.4 0.0079 15.9 1.5 3.5 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) DHH PF01368.20 ABK75992.1 - 3.9e-13 49.5 0.0 6.4e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 DHH family DHHA1 PF02272.19 ABK75992.1 - 8.2e-13 48.9 0.0 1.4e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 DHHA1 domain HAD_2 PF13419.6 ABK75993.1 - 1.2e-10 41.8 0.0 6.2e-10 39.4 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ABK75993.1 - 2e-08 34.8 0.0 2.6e-07 31.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ABK75993.1 - 1.9e-07 31.0 1.4 3.3e-07 30.3 0.2 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like MannoseP_isomer PF01050.18 ABK75993.1 - 0.18 11.7 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase DUF4072 PF13284.6 ABK75993.1 - 0.28 11.6 3.2 31 5.1 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4072) ABC_tran PF00005.27 ABK75994.1 - 7.4e-35 120.4 0.0 1.1e-34 119.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK75994.1 - 9.2e-11 42.1 0.2 3.2e-05 23.9 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 ABK75994.1 - 1.5e-05 25.2 0.2 9.2e-05 22.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ABK75994.1 - 1.8e-05 25.2 0.0 3.5e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ABK75994.1 - 2.2e-05 24.8 0.0 0.00015 22.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 ABK75994.1 - 2.2e-05 24.0 0.0 0.17 11.3 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ABK75994.1 - 5.4e-05 22.8 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 ABK75994.1 - 8.1e-05 22.5 0.0 0.024 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 ABK75994.1 - 0.00037 20.4 0.0 0.00086 19.2 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 ABK75994.1 - 0.0034 17.9 0.0 0.11 13.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ABK75994.1 - 0.0069 16.1 0.1 0.041 13.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 ABK75994.1 - 0.0076 15.8 0.1 0.087 12.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 ABK75994.1 - 0.01 16.2 0.0 0.16 12.4 0.0 2.2 2 0 0 2 2 2 0 RNA helicase MMR_HSR1 PF01926.23 ABK75994.1 - 0.031 14.4 0.0 0.069 13.2 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.14 ABK75994.1 - 0.035 14.1 0.1 0.097 12.7 0.0 1.7 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 ABK75994.1 - 0.044 13.5 0.0 0.81 9.4 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 ABK75994.1 - 0.047 13.4 0.0 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 ABK75994.1 - 0.048 12.9 0.0 4.3 6.5 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin PhoH PF02562.16 ABK75994.1 - 0.068 12.6 0.0 0.28 10.6 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein SbcCD_C PF13558.6 ABK75994.1 - 0.11 12.8 0.1 3 8.1 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 ABK75994.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 ABK75994.1 - 0.13 12.7 0.0 0.18 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 ABK75994.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 ABK75994.1 - 0.16 12.1 0.0 0.53 10.4 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain Rad17 PF03215.15 ABK75994.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain GCV_T PF01571.21 ABK75995.1 - 2e-21 76.5 0.0 5.1e-21 75.2 0.0 1.5 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 ABK75995.1 - 0.0036 17.2 0.0 0.012 15.5 0.0 1.9 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain BPD_transp_1 PF00528.22 ABK75996.1 - 5.6e-21 75.1 20.9 5.6e-21 75.1 20.9 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF3290 PF11694.8 ABK75996.1 - 7.4 6.5 5.4 4.1 7.4 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3290) Lactamase_B PF00753.27 ABK75997.1 - 2.2e-14 53.9 7.5 3.5e-14 53.3 7.5 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_5 PF14597.6 ABK75997.1 - 2.1e-05 24.1 0.0 2.6e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ABK75997.1 - 0.00054 19.5 1.9 0.00086 18.9 1.9 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ABK75997.1 - 0.0031 17.4 1.2 0.014 15.3 1.2 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DHDPS PF00701.22 ABK75999.1 - 2.5e-14 52.7 0.0 3.1e-14 52.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Pantoate_transf PF02548.15 ABK75999.1 - 1.3e-06 28.0 1.6 2.4e-06 27.1 1.6 1.4 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase adh_short_C2 PF13561.6 ABK76001.1 - 1.1e-59 201.9 0.0 1.3e-59 201.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK76001.1 - 1.7e-52 177.7 0.0 2e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK76001.1 - 7.5e-11 42.3 0.1 1.3e-10 41.4 0.1 1.4 1 1 0 1 1 1 1 KR domain DUF4113 PF13438.6 ABK76001.1 - 0.1 12.7 0.0 6.1 7.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4113) THF_DHG_CYH_C PF02882.19 ABK76001.1 - 0.1 11.9 0.0 1.9 7.8 0.0 2.1 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain PE PF00934.20 ABK76002.1 - 0.005 17.1 0.2 0.005 17.1 0.2 2.3 3 0 0 3 3 3 1 PE family Presenilin PF01080.17 ABK76002.1 - 0.36 9.6 1.8 0.35 9.6 1.8 1.1 1 0 0 1 1 1 0 Presenilin HrpB7 PF09486.10 ABK76002.1 - 0.69 10.3 13.5 0.28 11.6 11.0 1.5 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF5421 PF17458.2 ABK76002.1 - 0.91 8.9 4.3 1.5 8.2 4.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5421) DUF3552 PF12072.8 ABK76002.1 - 1.2 8.5 13.3 1.9 7.9 13.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Rrn6 PF10214.9 ABK76002.1 - 1.3 7.5 9.9 1.8 7.0 9.9 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor TFIIA PF03153.13 ABK76002.1 - 1.8 8.5 13.2 2.1 8.2 13.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peroxin-3 PF04882.12 ABK76002.1 - 9.6 5.1 7.8 18 4.1 7.8 1.5 1 1 0 1 1 1 0 Peroxin-3 Hydrolase_4 PF12146.8 ABK76003.1 - 8e-17 61.3 0.1 9.5e-17 61.1 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ABK76003.1 - 6.1e-11 43.3 5.6 8.3e-11 42.9 5.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ABK76003.1 - 7.3e-05 22.5 0.1 0.00014 21.6 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 ABK76003.1 - 0.00037 20.4 0.0 0.00061 19.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.12 ABK76003.1 - 0.0095 15.5 0.0 0.025 14.1 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.25 ABK76003.1 - 0.028 14.3 0.0 0.065 13.1 0.0 1.6 2 0 0 2 2 2 0 Lipase (class 3) Chlorophyllase2 PF12740.7 ABK76003.1 - 0.06 12.3 0.0 0.086 11.7 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase enzyme Acyl-CoA_dh_M PF02770.19 ABK76004.1 - 7.8e-22 77.3 0.0 1.4e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ABK76004.1 - 1.1e-21 77.5 0.1 2.1e-21 76.7 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 ABK76004.1 - 2.3e-06 27.9 0.6 9.6e-06 25.9 0.2 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acetyltransf_7 PF13508.7 ABK76005.1 - 2.5e-06 27.8 0.0 4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ABK76005.1 - 7.1e-06 25.9 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 ABK76005.1 - 1.8e-05 24.6 0.0 2.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ABK76005.1 - 5.3e-05 23.4 0.1 6.9e-05 23.1 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 ABK76005.1 - 0.044 13.9 0.0 0.38 10.9 0.0 2.1 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Glyoxalase_3 PF13468.6 ABK76005.1 - 0.077 13.1 0.3 0.27 11.3 0.1 2.0 2 1 0 2 2 2 0 Glyoxalase-like domain Bac_luciferase PF00296.20 ABK76006.1 - 6.2e-57 193.4 5.0 8.1e-57 193.0 5.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase SGL PF08450.12 ABK76007.1 - 7.5e-58 196.0 0.4 1.4e-57 195.1 0.4 1.4 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 ABK76007.1 - 9.5e-05 22.5 0.0 0.019 15.2 0.0 2.9 3 0 0 3 3 3 1 Arylesterase TAT_signal PF10518.9 ABK76007.1 - 0.00048 19.8 2.7 0.00077 19.2 2.7 1.3 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence Str_synth PF03088.16 ABK76007.1 - 0.0029 17.7 0.0 1.8 8.7 0.0 2.7 3 0 0 3 3 3 2 Strictosidine synthase DUF3659 PF12396.8 ABK76007.1 - 3.1 7.8 4.1 10 6.1 0.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3659) Cation_efflux PF01545.21 ABK76008.1 - 1.8e-12 47.4 12.5 1.1e-11 44.9 12.5 1.9 1 1 0 1 1 1 1 Cation efflux family SKG6 PF08693.10 ABK76009.1 - 0.015 14.7 2.3 0.023 14.1 2.3 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain LRRC37AB_C PF14914.6 ABK76009.1 - 0.068 13.1 0.7 0.12 12.3 0.7 1.3 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain EphA2_TM PF14575.6 ABK76009.1 - 0.16 12.8 0.3 0.31 12.0 0.3 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain tRNA_edit PF04073.15 ABK76010.1 - 1.3e-27 96.3 0.4 2e-27 95.7 0.4 1.3 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain CMD PF02627.20 ABK76011.1 - 0.048 13.7 0.2 0.11 12.6 0.2 1.6 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family Peripla_BP_4 PF13407.6 ABK76012.1 - 1.1e-63 215.2 5.7 1.4e-63 214.8 5.7 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 ABK76012.1 - 0.009 15.5 0.1 0.016 14.6 0.1 1.4 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LPAM_2 PF13627.6 ABK76012.1 - 0.11 12.3 3.1 0.21 11.5 3.1 1.5 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site TsaE PF02367.17 ABK76013.1 - 1.2e-30 106.0 0.0 1.5e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 ABK76013.1 - 0.00095 19.6 0.0 0.0011 19.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 ABK76013.1 - 0.0015 18.3 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 ABK76013.1 - 0.0015 18.3 0.2 0.0036 17.1 0.1 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 ABK76013.1 - 0.0022 18.5 0.0 0.0045 17.5 0.1 1.3 1 1 0 1 1 1 1 ABC transporter NACHT PF05729.12 ABK76013.1 - 0.0031 17.5 0.0 0.0038 17.1 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_7 PF12775.7 ABK76013.1 - 0.0059 16.1 0.0 0.0076 15.8 0.0 1.1 1 0 0 1 1 1 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 ABK76013.1 - 0.011 15.0 0.1 0.016 14.5 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.17 ABK76013.1 - 0.011 15.4 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 ABK76013.1 - 0.015 14.5 0.1 0.02 14.1 0.1 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_33 PF13671.6 ABK76013.1 - 0.018 15.2 0.1 0.035 14.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 ABK76013.1 - 0.031 13.9 0.3 0.06 12.9 0.3 1.5 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 ABK76013.1 - 0.033 14.6 0.2 0.054 13.9 0.2 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 ABK76013.1 - 0.053 13.9 0.0 0.068 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ABK76013.1 - 0.07 12.7 2.2 0.14 11.7 1.7 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 ABK76013.1 - 0.074 12.5 0.1 0.1 12.0 0.1 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_2 PF07724.14 ABK76013.1 - 0.11 12.6 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) NB-ARC PF00931.22 ABK76013.1 - 0.13 11.4 0.1 0.18 10.9 0.1 1.1 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 ABK76013.1 - 0.14 12.7 0.0 0.2 12.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain DnaB_C PF03796.15 ABK76013.1 - 0.22 10.8 0.1 0.43 9.9 0.1 1.6 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain RhaA PF06134.11 ABK76014.1 - 1.3e-06 27.8 0.0 1.9e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 L-rhamnose isomerase (RhaA) AP_endonuc_2 PF01261.24 ABK76014.1 - 0.0033 16.9 0.1 0.0077 15.7 0.1 1.6 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel LysR_substrate PF03466.20 ABK76015.1 - 8.5e-26 90.6 4.3 1.4e-25 89.9 4.3 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 ABK76015.1 - 9.7e-15 54.3 1.9 9.7e-15 54.3 0.4 1.8 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 ABK76015.1 - 0.002 18.0 2.8 0.015 15.2 0.3 2.6 2 0 0 2 2 2 1 MarR family HTH_28 PF13518.6 ABK76015.1 - 0.038 14.1 0.4 0.15 12.2 0.2 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_30 PF13556.6 ABK76015.1 - 0.064 13.1 0.1 0.18 11.7 0.1 1.7 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_20 PF12840.7 ABK76015.1 - 0.081 13.0 0.6 0.63 10.2 0.2 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_24 PF13412.6 ABK76015.1 - 0.2 11.3 1.4 0.94 9.1 0.1 2.6 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding EutC PF05985.11 ABK76016.1 - 6.3e-82 274.4 0.2 7.3e-82 274.2 0.2 1.0 1 0 0 1 1 1 1 Ethanolamine ammonia-lyase light chain (EutC) ParBc PF02195.18 ABK76016.1 - 0.047 14.0 0.1 1.5 9.2 0.0 2.2 2 0 0 2 2 2 0 ParB-like nuclease domain IMS PF00817.20 ABK76017.1 - 6.4e-36 123.6 0.0 9.7e-36 123.0 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 ABK76017.1 - 6.3e-18 65.6 0.3 1.4e-17 64.5 0.1 1.6 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 ABK76017.1 - 1.8e-06 27.9 0.1 4.7e-06 26.6 0.1 1.7 1 0 0 1 1 1 1 IMS family HHH motif ADH_N PF08240.12 ABK76018.1 - 5.2e-27 93.9 0.2 1.1e-26 92.9 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ABK76018.1 - 2.5e-22 79.3 0.0 3.6e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ABK76018.1 - 6.4e-05 22.5 0.1 9.7e-05 21.9 0.1 1.3 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 ABK76018.1 - 0.061 14.4 0.0 0.18 12.8 0.0 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 ABK76019.1 - 2.1e-12 46.9 0.0 7.2e-09 35.3 0.0 3.0 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ABK76019.1 - 1e-11 44.6 0.0 2.6e-10 40.1 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ABK76019.1 - 9e-10 37.6 0.2 5.7e-07 28.3 0.1 2.8 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ABK76019.1 - 1.5e-07 31.6 0.8 8.5e-07 29.1 0.1 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 ABK76019.1 - 1e-05 24.9 0.0 0.00041 19.6 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 ABK76019.1 - 3.1e-05 23.7 3.9 0.084 12.4 1.0 3.4 3 1 1 4 4 4 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ABK76019.1 - 0.0012 18.0 0.5 0.006 15.7 0.6 2.0 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.20 ABK76019.1 - 0.0041 17.2 0.4 0.05 13.7 0.0 2.4 3 0 0 3 3 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 ABK76019.1 - 0.0046 17.5 1.2 0.22 12.1 2.3 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ABK76019.1 - 0.0054 15.8 0.3 1.4 7.9 0.2 2.9 4 0 0 4 4 4 2 Lycopene cyclase protein FAD_binding_3 PF01494.19 ABK76019.1 - 0.007 15.7 1.1 0.069 12.4 1.2 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 ABK76019.1 - 0.028 14.4 0.2 19 5.2 0.4 3.6 4 0 0 4 4 4 0 FAD-NAD(P)-binding HI0933_like PF03486.14 ABK76019.1 - 0.067 11.9 0.8 2.5 6.7 2.1 2.3 2 0 0 2 2 2 0 HI0933-like protein adh_short_C2 PF13561.6 ABK76020.1 - 3.9e-57 193.5 2.3 4.9e-57 193.2 2.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK76020.1 - 3.6e-46 157.1 0.8 4.6e-46 156.7 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK76020.1 - 2.9e-06 27.3 1.4 8.4e-06 25.8 1.4 1.7 1 1 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 ABK76020.1 - 3.5e-06 27.2 1.0 6.4e-06 26.3 1.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Sacchrp_dh_NADP PF03435.18 ABK76020.1 - 2.3e-05 24.6 0.1 3.8e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 ABK76020.1 - 0.0024 17.4 0.8 0.33 10.4 0.8 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 ABK76020.1 - 0.027 14.4 1.0 0.044 13.7 1.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 ABK76020.1 - 0.032 13.6 0.1 0.049 13.0 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 ABK76020.1 - 0.052 13.8 0.3 0.091 13.0 0.3 1.4 1 0 0 1 1 1 0 TrkA-N domain Ectoine_synth PF06339.12 ABK76021.1 - 1.8e-55 186.6 0.1 2e-55 186.4 0.1 1.0 1 0 0 1 1 1 1 Ectoine synthase Cupin_2 PF07883.11 ABK76021.1 - 7.6e-07 28.8 0.4 1e-06 28.3 0.4 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 ABK76021.1 - 0.012 15.5 0.2 0.015 15.2 0.2 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain SWIB PF02201.18 ABK76021.1 - 0.064 13.1 0.0 8.1 6.4 0.0 2.1 2 0 0 2 2 2 0 SWIB/MDM2 domain Cupin_6 PF12852.7 ABK76021.1 - 0.07 12.9 0.0 0.081 12.6 0.0 1.1 1 0 0 1 1 1 0 Cupin TctA PF01970.16 ABK76022.1 - 4.7e-138 460.4 37.3 4.7e-138 460.4 37.3 1.4 2 0 0 2 2 2 1 Tripartite tricarboxylate transporter TctA family GCD14_N PF14801.6 ABK76023.1 - 3.4e-27 94.0 0.7 7.2e-27 93.0 0.7 1.6 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term GCD14 PF08704.10 ABK76023.1 - 4.9e-21 75.5 0.0 4.1e-19 69.2 0.0 2.4 1 1 1 2 2 2 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 ABK76023.1 - 1.7e-06 27.9 0.0 2.5e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 ABK76023.1 - 0.00043 20.9 0.0 0.0008 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 ABK76023.1 - 0.002 17.3 0.0 0.0025 16.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.6 ABK76023.1 - 0.049 13.5 0.0 0.079 12.8 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 ABK76023.1 - 0.069 12.9 0.0 0.16 11.7 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 ABK76023.1 - 0.11 13.2 0.0 0.22 12.3 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain SIS PF01380.22 ABK76024.1 - 2.1e-10 40.6 0.1 4.1e-10 39.6 0.1 1.4 1 0 0 1 1 1 1 SIS domain DUF3297 PF11730.8 ABK76025.1 - 1.1e-35 121.4 0.1 1.2e-35 121.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3297) LysR_substrate PF03466.20 ABK76026.1 - 1e-37 129.6 6.8 1.4e-37 129.1 6.8 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 ABK76026.1 - 2.6e-19 68.9 2.6 2.6e-19 68.9 2.6 3.0 3 0 0 3 3 3 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_24 PF13412.6 ABK76026.1 - 0.16 11.5 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF2277 PF10041.9 ABK76027.1 - 4.3e-32 110.3 0.8 4.9e-32 110.1 0.8 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2277) CPBP PF02517.16 ABK76028.1 - 3.4e-11 43.4 1.8 3.4e-11 43.4 1.8 2.0 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease DciA PF05258.12 ABK76028.1 - 0.12 12.8 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 Dna[CI] antecedent, DciA E1-N PF14463.6 ABK76028.1 - 0.25 11.1 7.4 0.41 10.5 1.1 2.7 2 1 1 3 3 3 0 E1 N-terminal domain DUF2236 PF09995.9 ABK76029.1 - 2.7e-53 181.5 0.2 3.9e-53 181.0 0.1 1.3 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Amidohydro_2 PF04909.14 ABK76030.1 - 2.7e-09 37.3 3.0 6.3e-09 36.0 3.0 1.9 1 1 0 1 1 1 1 Amidohydrolase RuvC PF02075.17 ABK76031.1 - 1.2e-60 203.7 0.5 1.5e-60 203.4 0.5 1.1 1 0 0 1 1 1 1 Crossover junction endodeoxyribonuclease RuvC 3-alpha PF03475.14 ABK76031.1 - 0.044 13.6 0.6 0.13 12.1 0.6 1.8 1 0 0 1 1 1 0 3-alpha domain Big_10 PF17964.1 ABK76034.1 - 7.3e-25 88.0 0.0 1.2e-24 87.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial Ig domain YkuD PF03734.14 ABK76034.1 - 1.6e-21 77.2 0.1 2.8e-21 76.5 0.1 1.4 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain Big_5 PF13205.6 ABK76034.1 - 0.035 14.8 0.0 0.12 13.1 0.0 1.8 1 1 0 1 1 1 0 Bacterial Ig-like domain DctM PF06808.12 ABK76035.1 - 1.2e-76 258.3 48.2 1.4e-76 258.0 48.2 1.0 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporter, DctM component HTH_Tnp_ISL3 PF13542.6 ABK76035.1 - 0.098 12.1 0.6 0.3 10.5 0.6 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 NiFeSe_Hases PF00374.19 ABK76036.1 - 4.1e-22 78.8 0.6 5.4e-12 45.4 0.2 3.1 3 0 0 3 3 3 3 Nickel-dependent hydrogenase PE-PPE PF08237.11 ABK76037.1 - 4.1e-54 183.5 0.0 5.7e-54 183.1 0.0 1.1 1 0 0 1 1 1 1 PE-PPE domain Beta-lactamase PF00144.24 ABK76038.1 - 8.7e-66 222.4 2.9 1e-65 222.2 2.9 1.0 1 0 0 1 1 1 1 Beta-lactamase HTH_18 PF12833.7 ABK76039.1 - 8.5e-22 77.2 0.6 1.6e-21 76.3 0.6 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain DJ-1_PfpI PF01965.24 ABK76039.1 - 1.4e-21 77.0 0.0 1.8e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family HTH_AraC PF00165.23 ABK76039.1 - 1e-19 70.1 0.1 8.6e-12 44.8 0.0 2.6 3 0 0 3 3 3 2 Bacterial regulatory helix-turn-helix proteins, AraC family TetR_N PF00440.23 ABK76039.1 - 0.0067 16.2 0.0 0.039 13.7 0.0 2.3 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_Tnp_ISL3 PF13542.6 ABK76039.1 - 0.04 13.3 0.2 0.12 11.8 0.2 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Acyl-CoA_dh_M PF02770.19 ABK76040.1 - 1.3e-21 76.6 0.0 2e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 ABK76040.1 - 4.9e-13 49.5 0.2 8.7e-13 48.7 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK76040.1 - 1.2e-06 29.1 0.0 2.3e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Abhydrolase_1 PF00561.20 ABK76041.1 - 1.3e-21 77.4 1.2 4.2e-21 75.8 1.2 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ABK76041.1 - 1.3e-16 61.8 14.5 1.6e-16 61.6 14.5 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ABK76041.1 - 6.1e-16 58.4 0.2 1e-15 57.7 0.2 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 ABK76041.1 - 3.7e-05 23.5 0.0 0.00092 19.0 0.0 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ABK76041.1 - 8.9e-05 22.1 0.6 0.0072 15.8 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 ABK76041.1 - 0.00038 20.3 0.0 5.3 6.8 0.1 3.1 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.10 ABK76041.1 - 0.00064 19.8 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Isochorismatase PF00857.20 ABK76042.1 - 3.7e-32 111.9 0.0 4.4e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family ABC_tran PF00005.27 ABK76043.1 - 5.5e-61 205.1 0.0 5.5e-34 117.6 0.0 2.2 2 0 0 2 2 2 2 ABC transporter oligo_HPY PF08352.12 ABK76043.1 - 4.4e-14 52.7 0.7 8.4e-06 26.2 0.3 2.4 2 0 0 2 2 2 2 Oligopeptide/dipeptide transporter, C-terminal region SMC_N PF02463.19 ABK76043.1 - 4.2e-13 49.2 0.0 2.8e-05 23.7 0.0 3.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ABK76043.1 - 4.9e-08 33.1 7.1 0.069 12.9 0.0 4.1 2 2 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ABK76043.1 - 8.7e-07 28.6 4.6 0.0074 16.0 0.4 2.6 2 1 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 ABK76043.1 - 1.1e-05 25.8 5.6 0.0081 16.4 0.5 3.7 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ABK76043.1 - 0.00011 22.7 7.3 0.039 14.3 1.1 2.6 2 2 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 ABK76043.1 - 0.0012 18.4 2.6 0.044 13.4 0.2 3.4 3 1 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 ABK76043.1 - 0.0027 17.6 0.6 0.32 10.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase IstB_IS21 PF01695.17 ABK76043.1 - 0.0031 17.3 1.6 0.48 10.1 0.0 3.2 3 0 0 3 3 3 1 IstB-like ATP binding protein MMR_HSR1 PF01926.23 ABK76043.1 - 0.0079 16.3 0.4 0.59 10.2 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase APS_kinase PF01583.20 ABK76043.1 - 0.015 15.2 1.9 0.03 14.2 0.2 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA PF00004.29 ABK76043.1 - 0.015 15.7 0.5 12 6.3 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 ABK76043.1 - 0.015 15.5 1.5 2 8.7 0.2 3.6 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 ABK76043.1 - 0.02 15.4 0.9 1.4 9.4 0.2 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 ABK76043.1 - 0.023 14.4 1.2 1.8 8.3 0.2 2.2 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 ABK76043.1 - 0.033 13.6 0.1 0.69 9.3 0.0 2.6 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 ABK76043.1 - 0.034 13.9 3.2 1.7 8.3 0.1 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_5 PF07728.14 ABK76043.1 - 0.047 13.7 3.2 3.8 7.5 0.2 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 ABK76043.1 - 0.048 13.2 0.7 7.7 6.0 0.1 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 ABK76043.1 - 0.068 12.9 11.3 0.44 10.2 1.8 3.3 2 2 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ABK76043.1 - 0.085 13.0 0.6 2.2 8.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 ABK76043.1 - 0.2 11.8 5.8 2.9 7.9 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain MeaB PF03308.16 ABK76043.1 - 0.41 9.6 6.8 2.9 6.8 0.5 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase PF06745.13 ABK76043.1 - 0.57 9.5 2.0 13 5.0 0.1 2.2 2 0 0 2 2 2 0 KaiC Hpr_kinase_C PF07475.12 ABK76043.1 - 0.61 9.6 4.3 5.4 6.5 0.8 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain NB-ARC PF00931.22 ABK76043.1 - 0.61 9.2 1.7 8.5 5.5 0.2 2.4 2 0 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.12 ABK76043.1 - 0.63 9.3 1.8 4.7 6.4 0.2 2.3 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.12 ABK76043.1 - 1.1 9.2 3.8 9 6.2 0.3 2.7 2 0 0 2 2 2 0 NACHT domain PRK PF00485.18 ABK76043.1 - 2.6 7.8 6.4 2.3 7.9 0.7 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family TetR_N PF00440.23 ABK76044.1 - 7e-05 22.5 0.1 0.00013 21.7 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 ABK76044.1 - 0.096 13.0 2.9 0.4 11.0 0.2 2.5 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain 3HCDH_N PF02737.18 ABK76045.1 - 2.2e-53 180.8 0.3 3.3e-53 180.2 0.3 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 ABK76045.1 - 5.2e-22 78.3 0.5 1.6e-21 76.7 0.1 2.0 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 ABK76045.1 - 1.8e-07 31.4 0.7 4.9e-07 30.0 0.2 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 ABK76045.1 - 1.9e-05 24.4 0.5 3.7e-05 23.4 0.5 1.6 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 ABK76045.1 - 0.00029 20.9 0.1 0.00073 19.5 0.1 1.6 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sacchrp_dh_NADP PF03435.18 ABK76045.1 - 0.01 16.1 0.1 0.02 15.1 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 ABK76045.1 - 0.011 15.8 0.1 0.025 14.7 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 ABK76045.1 - 0.037 13.5 0.1 0.059 12.8 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase F420_oxidored PF03807.17 ABK76045.1 - 0.042 14.4 0.6 0.099 13.2 0.6 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent XdhC_C PF13478.6 ABK76045.1 - 0.044 14.3 0.1 0.078 13.5 0.1 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain AlaDh_PNT_C PF01262.21 ABK76045.1 - 0.074 12.3 0.4 0.13 11.5 0.4 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ABK76045.1 - 0.082 12.3 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain B12-binding PF02310.19 ABK76045.1 - 0.2 11.7 1.4 0.99 9.5 0.1 2.4 2 0 0 2 2 2 0 B12 binding domain NmrA PF05368.13 ABK76045.1 - 0.25 10.8 1.3 0.32 10.5 0.3 1.6 2 0 0 2 2 2 0 NmrA-like family ThiF PF00899.21 ABK76045.1 - 2.5 7.4 5.2 16 4.8 5.1 2.1 1 1 0 1 1 1 0 ThiF family AMP-binding PF00501.28 ABK76046.1 - 2.1e-90 303.4 0.0 2.4e-90 303.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ABK76046.1 - 1.1e-16 61.6 0.0 5.5e-15 56.1 0.0 2.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF4157 PF13699.6 ABK76047.1 - 0.00067 19.8 0.2 0.0019 18.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4157) BSP PF04450.12 ABK76047.1 - 0.0086 15.9 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase of plants and bacteria DUF1570 PF07607.11 ABK76047.1 - 0.13 12.6 0.3 6 7.2 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1570) Epimerase PF01370.21 ABK76048.1 - 8e-43 146.6 0.1 2e-42 145.3 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ABK76048.1 - 6.6e-40 137.5 0.0 5.4e-39 134.5 0.0 2.2 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ABK76048.1 - 1.2e-17 63.8 0.0 3.3e-13 49.3 0.0 2.1 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ABK76048.1 - 2.2e-13 50.0 0.0 4.6e-13 48.9 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 ABK76048.1 - 6.1e-12 45.3 0.0 8.7e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 ABK76048.1 - 3.4e-10 40.1 0.2 9.1e-10 38.7 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 ABK76048.1 - 4.2e-06 26.1 0.1 0.079 12.1 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.13 ABK76048.1 - 0.00013 21.6 0.1 0.27 10.8 0.0 2.4 2 0 0 2 2 2 2 NmrA-like family adh_short PF00106.25 ABK76048.1 - 0.00039 19.9 0.0 0.0025 17.3 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 ABK76048.1 - 0.12 12.3 0.0 0.62 10.0 0.0 2.1 1 1 0 1 1 1 0 KR domain Mycobact_memb PF05423.13 ABK76049.1 - 1.6e-09 37.8 0.0 2.2e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Mycobacterium membrane protein HCV_NS5a_C PF12941.7 ABK76049.1 - 0.00068 19.6 0.5 0.0011 18.9 0.5 1.2 1 0 0 1 1 1 1 HCV NS5a protein C-terminal region CwsA PF10814.8 ABK76049.1 - 0.027 14.7 0.1 0.044 14.0 0.1 1.4 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA EpuA PF11772.8 ABK76049.1 - 0.066 12.9 1.6 0.1 12.3 0.5 1.8 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta Pex14_N PF04695.13 ABK76049.1 - 0.16 12.6 5.7 0.13 13.0 4.5 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Wzy_C PF04932.15 ABK76050.1 - 0.0034 17.0 0.1 0.013 15.2 0.0 2.0 1 1 1 2 2 2 1 O-Antigen ligase Oxidored_FMN PF00724.20 ABK76051.1 - 1.2e-47 162.9 0.0 9.9e-40 136.8 0.0 2.0 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 ABK76051.1 - 8.8e-06 25.0 0.0 0.0031 16.7 0.0 2.5 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 ABK76051.1 - 0.0076 15.7 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Histidine biosynthesis protein TMP-TENI PF02581.17 ABK76051.1 - 0.028 13.7 0.0 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 Thiamine monophosphate synthase NMO PF03060.15 ABK76051.1 - 0.045 13.1 0.1 0.86 8.9 0.0 2.1 2 0 0 2 2 2 0 Nitronate monooxygenase RepL PF05732.11 ABK76051.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) SPDY PF03771.16 ABK76051.1 - 0.16 11.9 2.0 9 6.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF317) DUF1906 PF08924.11 ABK76052.1 - 3.7e-37 128.4 1.3 4.6e-37 128.1 1.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1906) TAT_signal PF10518.9 ABK76052.1 - 0.018 14.9 4.6 0.018 14.9 4.6 2.7 3 1 0 3 3 3 0 TAT (twin-arginine translocation) pathway signal sequence Transpeptidase PF00905.22 ABK76053.1 - 2.1e-36 125.7 0.0 2.8e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain MecA_N PF05223.11 ABK76053.1 - 3.6e-21 75.6 0.0 5.4e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 NTF2-like N-terminal transpeptidase domain DUF4878 PF12870.7 ABK76053.1 - 0.014 15.7 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4878) Peptidase_M24 PF00557.24 ABK76054.1 - 3.3e-59 200.1 0.1 5.2e-59 199.5 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 ABK76054.1 - 3.2e-25 89.3 0.7 5.7e-25 88.5 0.7 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain SH3_3 PF08239.11 ABK76054.1 - 0.021 15.1 0.1 0.066 13.5 0.1 1.8 2 0 0 2 2 2 0 Bacterial SH3 domain RrnaAD PF00398.20 ABK76055.1 - 4.8e-37 127.5 0.0 5.4e-37 127.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 ABK76055.1 - 0.00096 19.8 0.0 0.0018 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK76055.1 - 0.0036 18.0 0.0 0.0061 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABK76055.1 - 0.0084 16.7 0.0 0.016 15.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABK76055.1 - 0.036 13.9 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain H2TH PF06831.14 ABK76055.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Formamidopyrimidine-DNA glycosylase H2TH domain ABC_tran PF00005.27 ABK76056.1 - 2.1e-32 112.5 0.0 2.6e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK76056.1 - 5e-09 36.4 2.9 0.00013 21.9 1.3 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system BCA_ABC_TP_C PF12399.8 ABK76056.1 - 8.3e-08 32.0 0.0 1.5e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter SMC_N PF02463.19 ABK76056.1 - 1.1e-06 28.3 1.5 0.022 14.2 0.2 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ABK76056.1 - 8.5e-06 26.4 0.0 9.5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ABK76056.1 - 8.8e-05 22.2 0.1 0.00027 20.6 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 ABK76056.1 - 0.00035 21.0 0.2 0.00084 19.8 0.2 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 ABK76056.1 - 0.00071 19.4 0.0 0.0012 18.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ABK76056.1 - 0.0015 18.4 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 ABK76056.1 - 0.0021 18.1 0.8 0.0039 17.3 0.2 1.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.6 ABK76056.1 - 0.0043 16.8 0.1 0.16 11.6 0.1 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ABK76056.1 - 0.0065 16.7 0.8 0.15 12.4 0.8 2.2 1 1 0 1 1 1 1 AAA domain KdpD PF02702.17 ABK76056.1 - 0.0075 15.8 0.1 0.0095 15.4 0.1 1.2 1 0 0 1 1 1 1 Osmosensitive K+ channel His kinase sensor domain AAA_5 PF07728.14 ABK76056.1 - 0.01 15.8 0.4 1.1 9.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 ABK76056.1 - 0.12 11.6 0.4 0.69 9.1 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain SRPRB PF09439.10 ABK76056.1 - 0.13 11.6 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 ABK76056.1 - 0.13 12.8 0.1 0.3 11.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 ABK76056.1 - 0.18 11.3 0.2 0.35 10.4 0.2 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B PALP PF00291.25 ABK76057.1 - 4.7e-54 183.8 2.3 5.9e-54 183.5 2.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Gmad2 PF10648.9 ABK76057.1 - 0.018 15.3 0.0 0.066 13.5 0.0 1.9 2 0 0 2 2 2 0 Immunoglobulin-like domain of bacterial spore germination rve PF00665.26 ABK76058.1 - 1.1e-23 83.7 0.0 1.7e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 ABK76058.1 - 9.5e-08 31.7 0.0 2.3e-07 30.5 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain rve_2 PF13333.6 ABK76058.1 - 0.00011 22.3 0.0 0.00018 21.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain MaoC_dehydrat_N PF13452.6 ABK76059.1 - 1.7e-26 92.9 0.1 1.9e-26 92.7 0.1 1.0 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase 4HBT PF03061.22 ABK76059.1 - 0.0087 16.4 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Transgly PF00912.22 ABK76060.1 - 2.8e-52 176.7 0.0 4.3e-52 176.2 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase Transpeptidase PF00905.22 ABK76060.1 - 3.3e-20 72.5 0.0 5.6e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain PASTA PF03793.19 ABK76060.1 - 3.4e-08 33.2 0.8 9.6e-08 31.8 0.8 1.8 1 0 0 1 1 1 1 PASTA domain Fer2 PF00111.27 ABK76062.1 - 8.1e-08 32.1 0.3 9.5e-08 31.9 0.3 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain LCM PF04072.14 ABK76063.1 - 4.6e-59 199.5 0.1 6.6e-59 199.0 0.1 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase DUF3558 PF12079.8 ABK76064.1 - 3.5 7.6 9.1 3.4 7.6 6.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3558) HisKA_3 PF07730.13 ABK76065.1 - 7.5e-13 48.8 5.2 7.5e-13 48.8 5.2 2.2 2 0 0 2 2 2 1 Histidine kinase Acyl-CoA_dh_N PF02771.16 ABK76066.1 - 1.9e-08 35.0 0.0 2.5e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cys_Met_Meta_PP PF01053.20 ABK76067.1 - 1.1e-127 425.7 0.0 1.3e-127 425.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 ABK76067.1 - 1.3e-07 31.3 2.1 1.9e-07 30.7 2.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 ABK76067.1 - 2.7e-07 29.9 0.2 4.9e-07 29.0 0.2 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 ABK76067.1 - 1.3e-06 27.9 0.0 1.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II GDC-P PF02347.16 ABK76067.1 - 0.013 14.3 0.0 0.017 13.9 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein DUF726 PF05277.12 ABK76068.1 - 1.1 8.1 4.6 1.2 7.9 4.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF726) PT-VENN PF04829.13 ABK76068.1 - 1.7 8.8 8.2 2.5 8.2 8.2 1.4 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif adh_short_C2 PF13561.6 ABK76070.1 - 2.4e-62 210.5 1.7 2.8e-62 210.3 1.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ABK76070.1 - 6.2e-57 192.2 0.9 7.5e-57 192.0 0.9 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ABK76070.1 - 1.3e-15 57.7 1.3 1.9e-15 57.3 1.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ABK76070.1 - 2.8e-08 33.6 0.7 1.7e-07 31.0 0.7 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 ABK76070.1 - 8.2e-06 25.4 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) 3Beta_HSD PF01073.19 ABK76070.1 - 0.00012 21.2 0.4 0.00021 20.4 0.4 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 ABK76070.1 - 0.00094 19.1 0.6 0.0013 18.6 0.6 1.2 1 0 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 ABK76070.1 - 0.0046 17.2 0.4 0.0092 16.2 0.4 1.4 1 0 0 1 1 1 1 TrkA-N domain GDP_Man_Dehyd PF16363.5 ABK76070.1 - 0.013 15.0 0.1 0.036 13.5 0.0 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 ABK76070.1 - 0.033 14.1 1.0 0.077 12.9 1.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 ABK76070.1 - 0.055 13.6 0.5 0.26 11.4 0.3 2.2 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 ABK76070.1 - 0.13 12.6 0.5 0.22 11.8 0.5 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain YAcAr PF10686.9 ABK76070.1 - 1 9.4 4.3 2.6 8.1 0.2 3.2 3 2 0 3 3 3 0 YspA, cpYpsA-related SLOG family Amidohydro_1 PF01979.20 ABK76071.1 - 1.2e-33 116.9 0.6 1.6e-33 116.5 0.6 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ABK76071.1 - 1.1e-09 38.3 6.0 1.1e-09 38.3 6.0 2.6 2 1 0 2 2 2 1 Amidohydrolase family Methyltransf_25 PF13649.6 ABK76073.1 - 4.5e-17 62.5 0.1 1.7e-16 60.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABK76073.1 - 1.3e-14 54.6 0.0 2.6e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABK76073.1 - 2.9e-10 40.2 0.0 3.9e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABK76073.1 - 1.3e-06 28.3 0.0 2.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK76073.1 - 1.3e-05 25.8 0.0 2.7e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 ABK76073.1 - 0.0034 17.0 0.0 0.0045 16.6 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 ABK76073.1 - 0.022 14.3 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Pyr_redox_3 PF13738.6 ABK76074.1 - 8.3e-19 68.0 0.0 4.4e-17 62.3 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ABK76074.1 - 4.2e-18 65.1 0.0 2.9e-16 59.0 0.0 2.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 ABK76074.1 - 3.6e-14 52.7 0.0 7.1e-11 41.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ABK76074.1 - 1.8e-12 47.3 0.0 1.1e-10 41.5 0.0 2.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 ABK76074.1 - 4.3e-09 36.0 0.1 4.6e-07 29.3 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 ABK76074.1 - 3e-06 27.0 4.1 0.0061 16.2 0.2 3.2 1 1 2 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ABK76074.1 - 8.7e-06 25.8 1.0 0.00032 20.7 0.0 3.3 4 0 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 ABK76074.1 - 3.3e-05 24.3 0.0 0.26 11.9 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ABK76074.1 - 0.00075 18.3 0.5 0.55 8.9 0.3 2.5 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_2 PF00890.24 ABK76074.1 - 0.0038 16.4 0.1 0.008 15.3 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 ABK76074.1 - 0.009 15.4 0.1 0.017 14.5 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 ABK76074.1 - 0.0099 15.1 0.0 0.027 13.7 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 ABK76074.1 - 0.025 13.7 0.0 0.11 11.6 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 ABK76074.1 - 0.029 14.8 0.0 0.67 10.4 0.0 2.6 2 2 0 2 2 2 0 Putative NAD(P)-binding DUF998 PF06197.13 ABK76074.1 - 0.046 13.3 7.6 0.31 10.6 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF998) Shikimate_DH PF01488.20 ABK76074.1 - 0.11 12.6 0.0 2.5 8.2 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 ABK76074.1 - 0.2 10.7 1.0 0.26 10.3 0.1 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Lipoprotein_21 PF14041.6 ABK76075.1 - 3.5e-16 59.1 0.4 2.3e-15 56.5 0.4 2.2 1 1 0 1 1 1 1 LppP/LprE lipoprotein DUF1180 PF06679.12 ABK76075.1 - 0.43 11.0 3.3 0.66 10.4 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) LPAM_2 PF13627.6 ABK76075.1 - 2.6 8.0 5.9 4.2 7.3 5.9 1.4 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site DUF3558 PF12079.8 ABK76075.1 - 9.7 6.1 13.9 9.8 6.1 13.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3558) FCD PF07729.12 ABK76076.1 - 4.6e-24 85.2 17.7 4.6e-24 85.2 17.7 1.7 2 0 0 2 2 2 1 FCD domain GntR PF00392.21 ABK76076.1 - 1.9e-16 59.5 0.4 4.4e-16 58.3 0.1 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 ABK76076.1 - 1.9e-05 24.5 0.1 7.5e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain Rrf2 PF02082.20 ABK76076.1 - 0.0072 16.7 0.3 0.023 15.1 0.0 2.0 2 0 0 2 2 2 1 Transcriptional regulator MarR_2 PF12802.7 ABK76076.1 - 0.0075 16.1 2.0 0.012 15.5 0.1 2.3 3 0 0 3 3 3 1 MarR family Fe_dep_repress PF01325.19 ABK76076.1 - 0.019 15.1 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Arteri_nsp7a PF16749.5 ABK76076.1 - 0.039 14.2 0.1 0.087 13.0 0.1 1.7 1 0 0 1 1 1 0 Arterivirus nonstructural protein 7 alpha MarR PF01047.22 ABK76076.1 - 0.051 13.5 0.0 0.16 11.9 0.0 1.9 1 0 0 1 1 1 0 MarR family HTH_41 PF14502.6 ABK76076.1 - 0.13 12.0 0.0 0.45 10.2 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_IclR PF09339.10 ABK76076.1 - 0.13 12.1 1.8 0.49 10.2 0.1 2.5 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_1 PF00126.27 ABK76076.1 - 0.16 12.0 4.6 0.89 9.6 0.1 2.9 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family TrbI PF03743.14 ABK76076.1 - 0.16 11.8 0.1 0.22 11.4 0.1 1.2 1 0 0 1 1 1 0 Bacterial conjugation TrbI-like protein DprA_WH PF17782.1 ABK76076.1 - 0.22 11.7 0.4 0.22 11.7 0.4 2.7 3 0 0 3 3 3 0 DprA winged helix domain HTH_3 PF01381.22 ABK76076.1 - 0.36 10.9 2.1 0.92 9.6 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix HTH_10 PF04967.12 ABK76076.1 - 0.58 10.0 2.9 0.93 9.3 0.1 2.6 3 0 0 3 3 3 0 HTH DNA binding domain Trypan_PARP PF05887.11 ABK76077.1 - 0.001 19.1 16.3 0.0017 18.3 16.3 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DUF4366 PF14283.6 ABK76077.1 - 0.036 14.1 0.8 0.069 13.2 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF4330 PF14221.6 ABK76077.1 - 0.18 12.0 1.4 0.31 11.3 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) Complex1_49kDa PF00346.19 ABK76078.1 - 1.4e-110 368.6 0.0 1.8e-110 368.3 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit SnoaL PF07366.12 ABK76079.1 - 3e-05 23.8 0.0 3.2e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase YukD PF08817.10 ABK76080.1 - 4.1e-18 65.8 0.1 1e-17 64.6 0.1 1.7 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD Ammonium_transp PF00909.21 ABK76081.1 - 4.1e-64 216.7 27.8 4.8e-64 216.5 27.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Pox_A14 PF05767.12 ABK76081.1 - 0.032 14.4 1.2 0.09 12.9 1.2 1.8 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Polyketide_cyc2 PF10604.9 ABK76083.1 - 2.8e-13 50.4 0.1 3.2e-13 50.2 0.1 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 ABK76083.1 - 1.7e-11 44.4 0.0 2.7e-11 43.8 0.0 1.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF2505 PF10698.9 ABK76083.1 - 0.00041 20.5 0.0 0.00052 20.2 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2505) ABC_tran PF00005.27 ABK76084.1 - 6.1e-30 104.5 0.0 8e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ABK76084.1 - 1.2e-11 45.0 1.3 1.1e-05 25.4 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ABK76084.1 - 0.0027 18.3 0.1 0.0035 17.9 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ABK76084.1 - 0.053 13.2 0.0 0.076 12.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF3584 PF12128.8 ABK76084.1 - 0.066 10.7 2.2 0.087 10.3 2.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_29 PF13555.6 ABK76084.1 - 0.073 12.8 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_13 PF13166.6 ABK76084.1 - 0.083 11.5 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ABK76084.1 - 0.15 12.6 0.0 0.29 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 ABK76084.1 - 0.23 11.0 0.3 0.39 10.3 0.3 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SLT_2 PF13406.6 ABK76085.1 - 1.2e-10 41.1 5.6 1.1e-09 38.0 0.6 2.2 1 1 1 2 2 2 2 Transglycosylase SLT domain MFS_1 PF07690.16 ABK76086.1 - 3.3e-18 65.7 51.6 2.3e-17 63.0 39.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Ribosomal_L11_N PF03946.14 ABK76087.1 - 1.5e-31 108.0 0.2 2.7e-31 107.2 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 ABK76087.1 - 5.2e-29 100.6 1.6 1e-28 99.6 1.6 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain SBP_bac_5 PF00496.22 ABK76087.1 - 0.032 13.2 0.1 0.034 13.1 0.1 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle Ring_hydroxyl_A PF00848.19 ABK76088.1 - 1.4e-42 146.1 0.0 2.2e-42 145.4 0.0 1.3 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 ABK76088.1 - 2e-16 59.7 0.1 6e-16 58.2 0.0 1.8 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 ABK76088.1 - 0.05 13.5 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 Rieske-like [2Fe-2S] domain Sugar-bind PF04198.13 ABK76089.1 - 1.8e-48 164.9 0.1 3.4e-48 164.0 0.1 1.4 1 1 0 1 1 1 1 Putative sugar-binding domain MarR_2 PF12802.7 ABK76089.1 - 1.2e-08 34.7 1.6 7e-08 32.2 0.1 2.4 2 0 0 2 2 2 1 MarR family Sigma70_r4_2 PF08281.12 ABK76089.1 - 1.1e-06 28.1 0.4 3.4e-06 26.6 0.1 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.6 ABK76089.1 - 2.6e-06 27.0 0.1 7.4e-06 25.6 0.1 1.8 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4 PF04545.16 ABK76089.1 - 1.7e-05 24.2 0.0 8.7e-05 22.0 0.0 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_Crp_2 PF13545.6 ABK76089.1 - 9e-05 22.4 0.0 0.00028 20.8 0.0 1.9 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR PF01047.22 ABK76089.1 - 0.00011 22.1 0.0 0.0003 20.7 0.0 1.7 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 ABK76089.1 - 0.00026 20.5 0.0 0.00057 19.4 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 ABK76089.1 - 0.00065 19.8 0.1 0.0015 18.6 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 ABK76089.1 - 0.0061 16.3 0.0 0.023 14.4 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 ABK76089.1 - 0.0084 16.4 0.3 0.0084 16.4 0.3 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain TrmB PF01978.19 ABK76089.1 - 0.01 15.7 0.0 0.079 12.9 0.0 2.2 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 ABK76089.1 - 0.011 15.5 0.2 0.041 13.7 0.1 2.1 2 0 0 2 2 1 0 IclR helix-turn-helix domain KORA PF16509.5 ABK76089.1 - 0.013 15.7 0.0 0.066 13.5 0.0 2.1 2 1 0 2 2 1 0 TrfB plasmid transcriptional repressor HTH_11 PF08279.12 ABK76089.1 - 0.018 15.0 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 HTH domain HTH_3 PF01381.22 ABK76089.1 - 0.019 15.0 0.0 0.048 13.7 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix Sigma70_ECF PF07638.11 ABK76089.1 - 0.025 14.5 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 ECF sigma factor Fe_dep_repress PF01325.19 ABK76089.1 - 0.029 14.6 0.4 0.072 13.3 0.0 1.8 2 0 0 2 2 1 0 Iron dependent repressor, N-terminal DNA binding domain Terminase_5 PF06056.12 ABK76089.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_36 PF13730.6 ABK76089.1 - 0.057 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 ABK76089.1 - 0.06 13.4 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix GntR PF00392.21 ABK76089.1 - 0.13 12.0 0.2 0.13 12.0 0.2 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_AsnC-type PF13404.6 ABK76089.1 - 0.14 12.0 1.3 0.44 10.4 0.1 2.4 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Cupin_2 PF07883.11 ABK76090.1 - 1.9e-17 62.7 0.1 3.2e-17 62.0 0.1 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 ABK76090.1 - 0.0054 16.3 0.0 0.0069 16.0 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 ABK76090.1 - 0.0081 16.1 0.0 0.015 15.2 0.0 1.6 1 1 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 ABK76090.1 - 0.013 15.2 0.2 0.028 14.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF861) EutQ PF06249.12 ABK76090.1 - 0.11 12.2 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Toprim_4 PF13662.6 ABK76091.1 - 4.9e-23 81.4 0.0 7.2e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 Toprim domain RecR PF02132.15 ABK76091.1 - 3.3e-14 52.2 2.9 6.3e-14 51.3 2.9 1.5 1 0 0 1 1 1 1 RecR protein Toprim PF01751.22 ABK76091.1 - 1.6e-11 44.3 0.0 6.1e-11 42.5 0.0 1.8 2 0 0 2 2 2 1 Toprim domain HHH PF00633.23 ABK76091.1 - 2.2e-06 27.2 0.4 3.1e-05 23.6 0.0 2.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 ABK76091.1 - 5.6e-05 23.7 0.3 0.0031 18.1 0.0 2.8 2 1 0 2 2 2 1 Helix-hairpin-helix domain HHH_8 PF14716.6 ABK76091.1 - 0.017 15.5 0.0 0.051 13.9 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain IMS_HHH PF11798.8 ABK76091.1 - 0.057 13.8 0.4 0.33 11.4 0.0 2.5 3 0 0 3 3 3 0 IMS family HHH motif zinc_ribbon_2 PF13240.6 ABK76091.1 - 0.075 12.8 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain HHH_3 PF12836.7 ABK76091.1 - 0.075 13.3 0.0 0.3 11.4 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif Aldo_ket_red PF00248.21 ABK76092.1 - 6.7e-61 206.0 0.0 7.8e-61 205.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PknH_C PF14032.6 ABK76094.1 - 4.7e-39 134.2 0.2 6e-39 133.9 0.2 1.1 1 0 0 1 1 1 1 PknH-like extracellular domain rve PF00665.26 ABK76095.1 - 1.9e-26 92.6 0.0 2.8e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 ABK76095.1 - 7.4e-09 35.3 0.0 1.4e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 ABK76095.1 - 9.8e-08 32.0 0.0 2.2e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 HTH-like domain HTH_29 PF13551.6 ABK76095.1 - 0.00012 22.1 0.1 0.00092 19.2 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn helix rve_2 PF13333.6 ABK76095.1 - 0.00017 21.7 0.0 0.0003 20.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain HTH_23 PF13384.6 ABK76095.1 - 0.00028 20.6 0.5 0.00086 19.0 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 ABK76095.1 - 0.0005 20.1 1.5 0.0015 18.6 0.0 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 ABK76095.1 - 0.0064 16.8 2.3 0.0097 16.2 0.0 2.2 2 0 0 2 2 2 1 Transposase Competence PF03772.16 ABK76096.1 - 7.3e-49 166.5 37.1 7.3e-49 166.5 37.1 2.2 2 0 0 2 2 2 1 Competence protein DUF4131 PF13567.6 ABK76096.1 - 4.3e-10 39.5 2.7 4.3e-10 39.5 2.7 5.2 3 1 2 5 5 5 2 Domain of unknown function (DUF4131) IMS PF00817.20 ABK76097.1 - 5.1e-14 52.5 0.1 9.3e-14 51.7 0.1 1.4 1 0 0 1 1 1 1 impB/mucB/samB family Aldedh PF00171.22 ABK76098.1 - 9.1e-144 479.4 1.0 1e-143 479.2 1.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF4081 PF13312.6 ABK76099.1 - 2.1e-38 130.7 1.9 2.3e-38 130.6 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4081) FR47 PF08445.10 ABK76099.1 - 5.3e-11 42.3 0.3 1.2e-10 41.3 0.1 1.6 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_1 PF00583.25 ABK76099.1 - 2.7e-08 34.0 0.3 4.2e-08 33.4 0.3 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ABK76099.1 - 5.8e-05 23.0 0.1 9.1e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ABK76099.1 - 0.00022 21.6 0.1 0.00043 20.6 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2993 PF11209.8 ABK76101.1 - 1.3e-22 81.1 6.7 1.8e-22 80.7 6.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2993) Isochorismatase PF00857.20 ABK76102.1 - 1.8e-29 103.2 0.4 2.1e-29 102.9 0.4 1.1 1 0 0 1 1 1 1 Isochorismatase family bPH_6 PF10756.9 ABK76102.1 - 0.083 13.0 1.4 0.14 12.2 1.4 1.4 1 0 0 1 1 1 0 Bacterial PH domain DUF4170 PF13773.6 ABK76102.1 - 0.12 12.6 0.2 0.29 11.3 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4170) TerC PF03741.16 ABK76103.1 - 2.3e-52 177.3 9.1 2.3e-52 177.3 9.1 1.6 2 0 0 2 2 2 1 Integral membrane protein TerC family SecE PF00584.20 ABK76103.1 - 1.7 8.7 0.0 1.7 8.7 0.0 4.2 7 0 0 7 7 7 0 SecE/Sec61-gamma subunits of protein translocation complex Rhodanese PF00581.20 ABK76104.1 - 6.2e-14 52.4 0.0 7.6e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain DUF1150 PF06620.11 ABK76104.1 - 0.06 13.5 0.0 0.091 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1150) UDG PF03167.19 ABK76105.1 - 2.8e-06 27.4 0.0 6.9e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily MS_channel PF00924.18 ABK76106.1 - 1.2e-31 109.8 0.0 2.1e-31 109.1 0.0 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel cNMP_binding PF00027.29 ABK76106.1 - 3e-13 49.7 0.1 4.7e-13 49.0 0.1 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain SP_C-Propep PF08999.10 ABK76106.1 - 0.042 13.6 0.2 0.16 11.8 0.1 1.9 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide Mycobact_memb PF05423.13 ABK76107.1 - 1.6e-60 203.1 0.0 1.7e-60 202.9 0.0 1.0 1 0 0 1 1 1 1 Mycobacterium membrane protein MFS_1 PF07690.16 ABK76108.1 - 4.9e-36 124.4 68.0 7.1e-24 84.4 22.4 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 ABK76108.1 - 5.1e-09 35.5 33.9 2.2e-08 33.4 14.7 3.1 3 1 1 4 4 4 2 Sugar (and other) transporter MFS_3 PF05977.13 ABK76108.1 - 0.23 9.8 36.6 0.51 8.7 11.7 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector MFS_1_like PF12832.7 ABK76108.1 - 0.24 10.2 27.3 0.078 11.8 5.5 3.4 2 2 1 3 3 3 0 MFS_1 like family FCD PF07729.12 ABK76110.1 - 1.1e-21 77.5 11.1 2.2e-21 76.6 11.1 1.5 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 ABK76110.1 - 2.1e-15 56.1 0.5 3.6e-15 55.4 0.5 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family SHR3_chaperone PF08229.11 ABK76110.1 - 0.046 12.7 0.0 0.07 12.1 0.0 1.3 1 0 0 1 1 1 0 ER membrane protein SH3 TPR_21 PF09976.9 ABK76111.1 - 8.3e-05 22.4 2.3 8.3e-05 22.4 2.3 1.5 2 0 0 2 2 2 1 Tetratricopeptide repeat-like domain PAP_PilO PF06864.12 ABK76111.1 - 0.02 13.7 0.9 0.045 12.6 0.4 1.7 1 1 1 2 2 2 0 Pilin accessory protein (PilO) DUF3318 PF11780.8 ABK76111.1 - 0.044 13.7 1.3 0.082 12.8 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) Glycos_transf_1 PF00534.20 ABK76112.1 - 4.4e-39 133.8 0.0 2.6e-38 131.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ABK76112.1 - 1.6e-31 109.6 3.2 2.9e-31 108.7 2.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 ABK76112.1 - 1.6e-27 96.9 12.1 1.6e-27 96.9 12.1 2.5 1 1 1 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 ABK76112.1 - 6.5e-26 91.3 0.2 1.2e-25 90.5 0.2 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 ABK76112.1 - 6.4e-07 29.7 0.0 1.2e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 ABK76112.1 - 0.00043 20.1 1.0 0.02 14.6 1.1 2.4 1 1 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_2 PF13477.6 ABK76112.1 - 0.064 13.3 0.0 13 5.8 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase 4-like PorA PF11271.8 ABK76113.1 - 0.022 14.1 1.5 0.024 13.9 1.5 1.0 1 0 0 1 1 1 0 Porin PorA GXGXG PF01493.19 ABK76114.1 - 2.3e-09 37.1 15.0 6.6e-09 35.6 15.0 1.6 1 1 0 1 1 1 1 GXGXG motif Amidase_5 PF05382.13 ABK76114.1 - 0.1 12.5 1.9 0.17 11.8 1.9 1.4 1 0 0 1 1 1 0 Bacteriophage peptidoglycan hydrolase Catalase PF00199.19 ABK76115.1 - 3.2e-179 596.0 0.0 3.9e-179 595.7 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 ABK76115.1 - 2.5e-18 66.0 0.0 5.5e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive DeoC PF01791.9 ABK76116.1 - 2.9e-18 66.3 8.3 4e-18 65.9 8.3 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase His_biosynth PF00977.21 ABK76116.1 - 0.0014 18.2 2.1 0.012 15.1 0.1 2.5 2 1 0 2 2 2 1 Histidine biosynthesis protein Beta_protein PF14350.6 ABK76116.1 - 0.16 11.4 0.1 0.24 10.8 0.1 1.2 1 0 0 1 1 1 0 Beta protein HTH_18 PF12833.7 ABK76117.1 - 7.2e-21 74.2 1.4 1.7e-20 73.1 1.3 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 ABK76117.1 - 1.8e-13 50.2 0.3 7.7e-12 45.0 0.2 2.5 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family Thiolase_N PF00108.23 ABK76118.1 - 4.1e-69 232.8 0.0 6.7e-69 232.1 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ABK76118.1 - 1.1e-42 144.6 0.4 2.9e-42 143.2 0.1 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ABK76118.1 - 5.8e-06 26.1 0.3 1.3e-05 24.9 0.3 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain HPP PF04982.13 ABK76119.1 - 4.1e-27 94.8 14.7 4.1e-27 94.8 14.7 1.8 2 0 0 2 2 2 1 HPP family DUF5518 PF17647.1 ABK76119.1 - 2.9 8.1 23.7 0.39 10.9 17.2 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5518) AA_permease_2 PF13520.6 ABK76120.1 - 1.5e-28 99.8 48.1 1.8e-28 99.5 48.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ABK76120.1 - 1.6e-23 83.0 39.3 2.5e-23 82.4 39.3 1.3 1 0 0 1 1 1 1 Amino acid permease MitoNEET_N PF10660.9 ABK76120.1 - 0.18 11.9 6.7 3 8.0 0.2 3.7 3 0 0 3 3 3 0 Iron-containing outer mitochondrial membrane protein N-terminus DUF1182 PF06681.13 ABK76120.1 - 1.1 8.9 7.9 0.49 10.0 3.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1182) SGL PF08450.12 ABK76121.1 - 3.2e-44 151.4 0.0 4e-44 151.0 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 ABK76121.1 - 2e-06 27.8 0.0 4.9e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.20 ABK76121.1 - 0.00076 19.6 0.0 0.0027 17.9 0.0 1.9 2 0 0 2 2 2 1 Arylesterase Lactonase PF10282.9 ABK76121.1 - 0.0021 17.4 0.0 0.0032 16.8 0.0 1.3 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller NHL PF01436.21 ABK76121.1 - 0.021 14.9 0.4 6.5 7.0 0.0 4.0 4 0 0 4 4 4 0 NHL repeat TetR_C_33 PF13305.6 ABK76122.1 - 5.2e-17 62.5 0.9 5.2e-17 62.5 0.9 1.7 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ABK76122.1 - 8.6e-09 35.1 0.4 1.6e-08 34.2 0.4 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_15 PF17918.1 ABK76122.1 - 0.0046 17.7 0.5 0.017 15.8 0.0 2.0 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain DUF2436 PF10365.9 ABK76122.1 - 0.019 14.8 0.0 0.025 14.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2436) MarR_2 PF12802.7 ABK76123.1 - 1.5e-15 56.8 1.3 2.1e-15 56.4 0.5 1.7 2 0 0 2 2 2 1 MarR family MarR PF01047.22 ABK76123.1 - 3.2e-11 43.0 0.0 5.3e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 ABK76123.1 - 6.2e-07 29.8 0.0 1.1e-06 29.1 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 ABK76123.1 - 9.9e-07 28.5 0.2 2.3e-06 27.3 0.2 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_Crp_2 PF13545.6 ABK76123.1 - 0.00012 21.9 0.1 0.0002 21.3 0.1 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_24 PF13412.6 ABK76123.1 - 0.00013 21.4 0.0 0.00047 19.7 0.0 1.9 1 1 1 2 2 2 1 Winged helix-turn-helix DNA-binding GntR PF00392.21 ABK76123.1 - 0.00024 20.7 0.2 0.00067 19.3 0.1 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family TrmB PF01978.19 ABK76123.1 - 0.0016 18.3 0.0 0.0065 16.3 0.0 1.9 1 1 1 2 2 2 1 Sugar-specific transcriptional regulator TrmB AbiEi_4 PF13338.6 ABK76123.1 - 0.0096 16.1 0.6 0.068 13.3 0.3 2.4 1 1 1 2 2 2 1 Transcriptional regulator, AbiEi antitoxin Rrf2 PF02082.20 ABK76123.1 - 0.015 15.6 0.0 0.03 14.7 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator T3SS_LEE_assoc PF13327.6 ABK76123.1 - 0.11 12.6 0.2 0.23 11.5 0.1 1.6 1 1 1 2 2 2 0 Type III secretion system subunit HTH_CodY PF08222.11 ABK76123.1 - 0.14 11.8 0.1 0.25 10.9 0.1 1.4 1 0 0 1 1 1 0 CodY helix-turn-helix domain Mycobact_memb PF05423.13 ABK76124.1 - 2.1e-33 115.2 0.0 2.5e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Mycobacterium membrane protein DNA_ligase_A_M PF01068.21 ABK76125.1 - 6.2e-34 117.4 0.0 8.7e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 ABK76125.1 - 2.3e-16 60.2 0.0 4.6e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region AAA_29 PF13555.6 ABK76126.1 - 5.8e-22 77.2 0.1 1.3e-21 76.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 ABK76126.1 - 1.2e-19 70.4 0.2 3.6e-19 68.8 0.2 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 ABK76126.1 - 7.8e-10 39.6 2.7 2.3e-09 38.0 0.1 2.8 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.19 ABK76126.1 - 4e-06 26.4 0.1 6.1e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ABK76126.1 - 0.00033 20.6 0.2 0.00077 19.4 0.2 1.6 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Flagellin_C PF00700.21 ABK76126.1 - 0.0053 17.1 0.5 0.025 14.9 0.5 2.3 1 0 0 1 1 1 1 Bacterial flagellin C-terminal helical region ABC_tran PF00005.27 ABK76126.1 - 0.024 15.2 0.5 0.23 12.0 0.0 2.7 2 0 0 2 2 2 0 ABC transporter AAA_15 PF13175.6 ABK76126.1 - 0.028 14.1 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain QRPTase_C PF01729.19 ABK76126.1 - 0.048 13.4 0.5 0.17 11.7 0.1 2.0 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain YkyA PF10368.9 ABK76126.1 - 0.066 12.9 1.5 7.7 6.1 0.1 2.8 2 1 0 2 2 2 0 Putative cell-wall binding lipoprotein AAA_16 PF13191.6 ABK76126.1 - 0.087 13.2 0.1 0.087 13.2 0.1 3.9 2 1 0 2 2 2 0 AAA ATPase domain NPV_P10 PF05531.12 ABK76126.1 - 0.16 12.4 9.1 5.8 7.5 1.4 4.4 4 0 0 4 4 3 0 Nucleopolyhedrovirus P10 protein DUF5082 PF16888.5 ABK76126.1 - 0.17 12.2 10.5 0.63 10.3 0.4 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) Syntaxin_2 PF14523.6 ABK76126.1 - 0.3 11.5 3.9 7 7.1 0.5 3.6 4 1 1 5 5 4 0 Syntaxin-like protein DUF948 PF06103.11 ABK76126.1 - 0.68 10.2 4.0 9.5 6.6 0.1 4.2 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) BRE1 PF08647.11 ABK76126.1 - 0.7 10.0 6.0 1 9.5 0.1 3.4 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase DUF16 PF01519.16 ABK76126.1 - 0.76 10.3 5.5 1.8 9.1 1.0 2.8 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF3450 PF11932.8 ABK76126.1 - 1.3 8.2 14.5 0.43 9.9 2.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) AAA_22 PF13401.6 ABK76126.1 - 2.4 8.4 4.2 4.5 7.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain Troponin PF00992.20 ABK76126.1 - 5.6 7.3 7.0 2.4 8.4 0.4 2.9 2 0 0 2 2 2 0 Troponin DUF4200 PF13863.6 ABK76126.1 - 7.7 6.9 9.6 11 6.4 3.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Spc7 PF08317.11 ABK76126.1 - 8.6 5.1 16.6 3 6.6 4.3 2.8 2 1 1 3 3 3 0 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.9 ABK76126.1 - 8.7 6.5 13.2 0.61 10.3 1.2 2.9 2 2 0 2 2 2 0 JNK_SAPK-associated protein-1 SBP_bac_1 PF01547.25 ABK76127.1 - 1.2e-29 104.3 16.1 2.1e-29 103.5 16.1 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 ABK76127.1 - 5.5e-24 85.5 12.1 9.2e-24 84.7 12.1 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein TAT_signal PF10518.9 ABK76127.1 - 0.028 14.3 2.0 0.054 13.3 2.0 1.5 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence HTH_3 PF01381.22 ABK76128.1 - 0.00011 22.1 0.0 0.00025 21.1 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 ABK76128.1 - 0.0017 18.6 0.3 0.019 15.3 0.0 2.5 2 2 0 2 2 2 1 Helix-turn-helix domain HTH_26 PF13443.6 ABK76128.1 - 0.16 12.4 0.0 0.4 11.2 0.0 1.6 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Aldedh PF00171.22 ABK76129.1 - 2.5e-110 369.2 2.1 2.8e-110 369.0 2.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Amidohydro_2 PF04909.14 ABK76131.1 - 1.4e-38 133.3 1.1 1.6e-38 133.2 1.1 1.0 1 0 0 1 1 1 1 Amidohydrolase TetR_N PF00440.23 ABK76132.1 - 1.6e-08 34.2 0.1 5.8e-08 32.4 0.1 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family RS4NT PF08071.12 ABK76132.1 - 0.046 13.8 0.1 0.075 13.2 0.1 1.3 1 0 0 1 1 1 0 RS4NT (NUC023) domain Aldo_ket_red PF00248.21 ABK76133.1 - 2.7e-74 250.0 0.0 3.1e-74 249.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ADH_N PF08240.12 ABK76134.1 - 7.3e-11 41.9 0.0 1.5e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ABK76134.1 - 7.6e-07 30.3 0.0 1.3e-06 29.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ABK76134.1 - 0.00017 21.6 0.0 0.00028 20.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PfkB PF00294.24 ABK76135.1 - 9.6e-40 136.7 0.2 1.2e-39 136.4 0.2 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase tRNA_synt_2f PF02092.17 ABK76135.1 - 0.28 10.1 0.1 0.39 9.6 0.1 1.1 1 0 0 1 1 1 0 Glycyl-tRNA synthetase beta subunit DUF4802 PF16060.5 ABK76135.1 - 0.31 11.2 0.5 0.55 10.4 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4802) Guanylate_cyc PF00211.20 ABK76136.1 - 2.5e-19 69.6 0.0 3.8e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HAMP PF00672.25 ABK76136.1 - 1.4e-09 38.2 1.2 1.8e-09 37.8 0.1 1.9 2 0 0 2 2 2 1 HAMP domain TMEM240 PF15207.6 ABK76136.1 - 0.12 12.1 0.1 0.34 10.6 0.1 1.7 1 0 0 1 1 1 0 TMEM240 family Saf_2TM PF18303.1 ABK76136.1 - 1.2 8.7 4.1 2.5 7.7 0.1 2.4 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain Putative_PNPOx PF01243.20 ABK76137.1 - 3.6e-07 30.3 0.0 4.7e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 ABK76137.1 - 0.0086 16.1 0.1 0.016 15.2 0.1 1.4 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF2255 PF10012.9 ABK76137.1 - 0.014 15.5 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) zf-CGNR PF11706.8 ABK76138.1 - 4.2e-18 64.9 7.0 6.6e-18 64.3 7.0 1.3 1 0 0 1 1 1 1 CGNR zinc finger ABATE PF07336.11 ABK76138.1 - 1.2e-06 29.2 7.4 1.8e-06 28.6 7.4 1.2 1 0 0 1 1 1 1 Putative stress-induced transcription regulator POR_N PF01855.19 ABK76139.1 - 2.4e-58 197.6 0.0 3.8e-58 197.0 0.0 1.2 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 ABK76139.1 - 1e-26 94.1 0.0 1.6e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 ABK76139.1 - 2.5e-08 34.2 0.0 4.5e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II TPP_enzyme_N PF02776.18 ABK76139.1 - 1.2e-05 24.9 0.0 2.5e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain ATP-synt_D PF01813.17 ABK76139.1 - 0.042 13.7 0.0 0.074 12.9 0.0 1.3 1 0 0 1 1 1 0 ATP synthase subunit D Transketolase_C PF02780.20 ABK76139.1 - 0.093 12.6 0.0 0.32 10.9 0.0 1.8 2 0 0 2 2 2 0 Transketolase, C-terminal domain Uricase PF01014.18 ABK76140.1 - 3.1e-55 186.0 0.1 4.5e-31 107.8 0.0 2.1 2 0 0 2 2 2 2 Uricase Ribosomal_S13 PF00416.22 ABK76141.1 - 0.023 15.1 0.0 0.034 14.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S13/S18 RPN13_C PF16550.5 ABK76141.1 - 0.034 14.3 0.1 0.051 13.8 0.1 1.4 1 1 0 1 1 1 0 UCH-binding domain MgtE_N PF03448.17 ABK76141.1 - 0.2 12.3 2.4 0.88 10.2 0.2 2.1 1 1 0 1 1 1 0 MgtE intracellular N domain YGGT PF02325.17 ABK76142.1 - 6.7e-12 45.7 7.1 8.7e-12 45.3 7.1 1.2 1 0 0 1 1 1 1 YGGT family Sigma70_r2 PF04542.14 ABK76143.1 - 1.9e-15 56.4 1.9 3.1e-15 55.7 1.9 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 ABK76143.1 - 1.9e-11 43.5 0.0 3.8e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 ABK76143.1 - 1.8e-05 24.2 0.0 6.2e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 ABK76143.1 - 0.0073 16.2 0.1 0.0099 15.8 0.1 1.2 1 0 0 1 1 1 1 ECF sigma factor Fis1_TPR_C PF14853.6 ABK76143.1 - 0.22 11.6 1.0 35 4.6 0.1 3.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat ECH_1 PF00378.20 ABK76145.1 - 4.3e-32 111.4 0.0 4.3e-19 68.8 0.1 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK76145.1 - 2.1e-17 63.7 0.0 9.6e-17 61.5 0.0 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase SDH_sah PF01972.16 ABK76145.1 - 0.0097 14.9 0.1 0.017 14.2 0.1 1.3 1 0 0 1 1 1 1 Serine dehydrogenase proteinase ACP_syn_III_C PF08541.10 ABK76145.1 - 0.046 13.9 0.0 0.2 11.9 0.0 2.0 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF3756 PF12581.8 ABK76145.1 - 0.13 12.2 0.2 0.34 10.9 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3756) APH PF01636.23 ABK76146.1 - 1.1e-33 117.1 3.3 1.6e-33 116.7 3.3 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 ABK76146.1 - 3.2e-06 26.7 0.0 4.5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 ABK76146.1 - 0.025 14.2 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.11 ABK76146.1 - 0.04 12.8 0.0 0.058 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Kdo PF06293.14 ABK76146.1 - 0.078 12.3 0.0 16 4.7 0.0 2.9 3 1 1 4 4 4 0 Lipopolysaccharide kinase (Kdo/WaaP) family FANC_SAP PF18081.1 ABK76146.1 - 2.3 8.4 6.1 2.7 8.2 0.0 2.9 3 0 0 3 3 3 0 Fanconi anemia-associated nuclease SAP domain FtsK_SpoIIIE PF01580.18 ABK76147.1 - 9.3e-66 221.6 0.3 8.8e-64 215.2 0.3 2.2 1 1 0 1 1 1 1 FtsK/SpoIIIE family FtsK_alpha PF17854.1 ABK76147.1 - 6.1e-28 96.9 0.0 1.2e-27 96.0 0.0 1.5 1 0 0 1 1 1 1 FtsK alpha domain FtsK_gamma PF09397.10 ABK76147.1 - 8.3e-24 83.2 0.0 1.9e-23 82.0 0.0 1.6 1 0 0 1 1 1 1 Ftsk gamma domain DUF87 PF01935.17 ABK76147.1 - 1.4e-05 25.3 0.0 2.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Helicase HerA, central domain FtsK_4TM PF13491.6 ABK76147.1 - 0.0003 20.5 4.9 0.0003 20.5 4.9 1.5 1 1 0 1 1 1 1 4TM region of DNA translocase FtsK/SpoIIIE AAA_10 PF12846.7 ABK76147.1 - 0.00071 18.6 0.0 0.024 13.6 0.0 2.1 2 0 0 2 2 2 1 AAA-like domain Adeno_IVa2 PF02456.15 ABK76147.1 - 0.0069 15.2 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 Adenovirus IVa2 protein T2SSE PF00437.20 ABK76147.1 - 0.0074 15.4 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 ABK76147.1 - 0.011 14.7 0.0 0.027 13.4 0.0 1.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF815 PF05673.13 ABK76147.1 - 0.027 13.6 0.0 0.047 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 ABK76147.1 - 0.027 14.2 0.1 0.068 12.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 ABK76147.1 - 0.045 14.1 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 ABK76147.1 - 0.24 10.7 0.0 0.39 10.0 0.0 1.2 1 0 0 1 1 1 0 Septin Amidohydro_3 PF07969.11 ABK76148.1 - 1.2e-11 44.8 3.1 6.2e-05 22.7 0.2 3.2 3 0 0 3 3 3 3 Amidohydrolase family Amidohydro_1 PF01979.20 ABK76148.1 - 2.2e-11 43.7 1.8 1.9e-09 37.3 1.8 2.3 1 1 0 1 1 1 1 Amidohydrolase family Ribosomal_L9_C PF03948.14 ABK76149.1 - 3e-26 91.7 1.2 4.4e-26 91.2 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L9, C-terminal domain Ribosomal_L9_N PF01281.19 ABK76149.1 - 1.5e-19 69.3 0.0 2.7e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain FA_desaturase PF00487.24 ABK76150.1 - 9e-31 107.6 5.6 1.2e-30 107.2 5.6 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Acyl-CoA_dh_1 PF00441.24 ABK76151.1 - 1.6e-30 106.3 17.0 6.1e-17 62.2 6.5 2.3 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ABK76151.1 - 2.4e-21 76.5 2.9 2.3e-09 37.9 0.6 2.8 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ABK76151.1 - 8.8e-19 67.5 0.0 3.4e-18 65.6 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Bac_luciferase PF00296.20 ABK76152.1 - 2.9e-20 73.0 10.6 3.9e-20 72.5 10.6 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF3606 PF12244.8 ABK76152.1 - 0.072 13.0 0.1 19 5.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) Pyr_redox_2 PF07992.14 ABK76153.1 - 4.6e-52 177.1 2.9 5.2e-52 176.9 2.9 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ABK76153.1 - 1.2e-24 87.1 0.2 3.6e-19 69.2 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ABK76153.1 - 2.5e-22 79.2 1.1 1.3e-20 73.7 0.1 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ABK76153.1 - 2.7e-12 46.5 8.5 8.8e-06 25.0 0.2 4.5 2 2 3 5 5 5 3 FAD binding domain DAO PF01266.24 ABK76153.1 - 1.3e-10 41.5 7.1 0.015 14.9 0.1 4.1 3 1 1 4 4 4 3 FAD dependent oxidoreductase K_oxygenase PF13434.6 ABK76153.1 - 2.3e-08 33.6 0.6 0.018 14.2 0.0 3.3 2 1 1 3 3 3 3 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 ABK76153.1 - 8.4e-08 32.0 5.0 1.6e-06 27.8 1.2 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 ABK76153.1 - 8.9e-07 28.4 0.0 0.0002 20.7 0.0 2.5 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 ABK76153.1 - 1.3e-06 27.4 0.4 0.00068 18.5 0.1 3.3 3 1 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.6 ABK76153.1 - 1.9e-06 28.0 0.1 0.00029 21.0 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 ABK76153.1 - 6.5e-05 22.2 4.0 0.0029 16.7 0.3 3.4 3 2 0 4 4 4 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 ABK76153.1 - 6.7e-05 22.3 1.0 0.27 10.4 0.0 3.1 2 1 1 3 3 3 2 FAD binding domain NAD_binding_7 PF13241.6 ABK76153.1 - 0.0014 19.0 0.2 0.019 15.4 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding Trp_halogenase PF04820.14 ABK76153.1 - 0.0027 16.6 0.1 0.27 10.0 0.1 2.3 2 0 0 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.12 ABK76153.1 - 0.0054 15.8 0.4 1.4 7.9 0.0 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein DUF2190 PF09956.9 ABK76153.1 - 5.6 7.5 6.8 1.6 9.3 1.0 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2190) 2-Hacid_dh_C PF02826.19 ABK76154.1 - 4.2e-54 182.6 0.0 6.3e-54 182.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ABK76154.1 - 2.4e-12 46.7 0.0 3.7e-12 46.1 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ApbA PF02558.16 ABK76154.1 - 5.7e-05 22.8 0.2 0.00012 21.8 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA IlvN PF07991.12 ABK76154.1 - 0.00011 21.8 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 ABK76154.1 - 0.00027 21.4 0.1 0.0005 20.6 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 ABK76154.1 - 0.014 15.6 0.1 0.02 15.0 0.1 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 ABK76154.1 - 0.023 14.8 0.0 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 ABK76154.1 - 0.071 13.6 0.0 0.18 12.3 0.0 1.7 1 1 0 1 1 1 0 XdhC Rossmann domain Pyr_redox PF00070.27 ABK76154.1 - 0.13 12.8 0.3 0.29 11.7 0.3 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RmlD_sub_bind PF04321.17 ABK76154.1 - 0.17 11.0 0.0 0.25 10.4 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain 3HCDH_N PF02737.18 ABK76154.1 - 0.18 11.7 0.2 0.27 11.1 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CMAS PF02353.20 ABK76155.1 - 2.8e-120 400.7 0.0 3.2e-120 400.5 0.0 1.0 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 ABK76155.1 - 1.1e-10 42.1 0.0 2.4e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ABK76155.1 - 7.1e-09 36.2 0.0 1.4e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ABK76155.1 - 8.1e-09 35.5 0.0 1e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ABK76155.1 - 1.3e-06 29.1 0.0 2.5e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ABK76155.1 - 0.015 15.1 0.0 0.038 13.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Arg_decarb_HB PF17810.1 ABK76155.1 - 0.077 13.3 0.1 0.21 11.9 0.1 1.8 1 0 0 1 1 1 0 Arginine decarboxylase helical bundle domain PCMT PF01135.19 ABK76155.1 - 0.098 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 ABK76155.1 - 0.17 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Amidase PF01425.21 ABK76156.1 - 6.3e-72 243.0 1.3 1.4e-71 241.8 1.3 1.5 1 1 0 1 1 1 1 Amidase DDE_Tnp_ISL3 PF01610.17 ABK76157.1 - 1.6e-64 217.9 0.0 2.1e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Transposase zf-ISL3 PF14690.6 ABK76157.1 - 1.1e-09 38.8 4.6 1.8e-09 38.1 2.5 2.5 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HTH_Tnp_ISL3 PF13542.6 ABK76157.1 - 2.4e-08 33.2 1.6 7e-08 31.8 1.6 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 PucR PF07905.11 ABK76158.1 - 2.2e-18 66.6 0.1 6.1e-18 65.2 0.1 1.8 1 0 0 1 1 1 1 Purine catabolism regulatory protein-like family HTH_30 PF13556.6 ABK76158.1 - 2.2e-17 62.6 1.6 5.3e-17 61.4 1.6 1.7 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_1 PF00126.27 ABK76158.1 - 0.0051 16.7 2.2 0.011 15.7 0.2 2.4 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family DUF2567 PF10821.8 ABK76159.1 - 1.9e-75 252.5 16.1 2.3e-75 252.2 16.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2567) AA_permease_2 PF13520.6 ABK76160.1 - 2.1e-28 99.3 46.2 2.1e-28 99.3 46.2 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ABK76160.1 - 2e-22 79.5 45.8 3.7e-22 78.6 45.8 1.4 1 1 0 1 1 1 1 Amino acid permease EBP PF05241.12 ABK76161.1 - 2.7e-10 40.0 4.6 3.4e-10 39.7 4.6 1.1 1 0 0 1 1 1 1 Emopamil binding protein DUF2178 PF09946.9 ABK76161.1 - 0.18 12.0 1.8 9.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2178) DUF2781 PF10914.8 ABK76161.1 - 0.24 11.8 6.3 1.8 9.0 1.6 2.4 1 1 2 3 3 2 0 Protein of unknown function (DUF2781) Big_10 PF17964.1 ABK76162.1 - 0.14 12.2 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial Ig domain SecB PF02556.14 ABK76162.1 - 0.2 11.5 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit SecB Dus PF01207.17 ABK76164.1 - 1.1e-111 372.9 0.0 1.3e-111 372.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 ABK76164.1 - 0.052 12.8 0.0 1.5 7.9 0.0 2.1 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase DUF3736 PF12540.8 ABK76164.1 - 0.086 13.0 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3736) PAP2_3 PF14378.6 ABK76165.1 - 7.5e-26 91.0 17.1 7.5e-26 91.0 17.1 2.5 2 1 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 ABK76165.1 - 1.4e-09 37.8 4.1 1.4e-09 37.8 4.1 3.1 3 0 0 3 3 3 1 PAP2 superfamily PAP2_C PF14360.6 ABK76165.1 - 3.7e-05 24.2 0.9 3.7e-05 24.2 0.9 2.2 3 0 0 3 3 3 1 PAP2 superfamily C-terminal AzlD PF05437.12 ABK76165.1 - 0.037 14.2 0.1 0.037 14.2 0.1 3.4 3 1 0 3 3 3 0 Branched-chain amino acid transport protein (AzlD) DUF1475 PF07343.11 ABK76165.1 - 0.054 13.3 0.2 0.054 13.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1475) Aminotran_1_2 PF00155.21 ABK76166.1 - 6.2e-30 104.6 0.0 8.1e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 ABK76166.1 - 4.8e-15 55.0 1.3 1.6e-14 53.3 0.2 2.6 3 0 0 3 3 3 1 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 ABK76166.1 - 0.00083 19.3 0.1 0.00083 19.3 0.1 1.9 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain Fe_dep_repress PF01325.19 ABK76166.1 - 0.0012 19.0 0.0 0.0025 17.9 0.0 1.5 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Rrf2 PF02082.20 ABK76166.1 - 0.0031 17.8 0.1 0.0098 16.2 0.0 1.8 2 0 0 2 2 2 1 Transcriptional regulator HTH_24 PF13412.6 ABK76166.1 - 0.0062 16.1 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding DegT_DnrJ_EryC1 PF01041.17 ABK76166.1 - 0.02 14.2 0.1 0.036 13.4 0.1 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family MarR_2 PF12802.7 ABK76166.1 - 0.02 14.7 0.2 0.12 12.3 0.2 2.3 1 0 0 1 1 1 0 MarR family HTH_11 PF08279.12 ABK76166.1 - 0.032 14.2 1.2 0.044 13.7 0.0 1.8 2 0 0 2 2 2 0 HTH domain MFS_1 PF07690.16 ABK76167.1 - 6.6e-24 84.5 55.2 1e-15 57.6 26.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 ABK76167.1 - 0.038 12.8 21.7 0.31 9.8 2.3 3.0 1 1 2 3 3 3 0 MFS_1 like family GMP_synt_C PF00958.22 ABK76167.1 - 0.2 11.8 0.0 0.42 10.7 0.0 1.5 1 0 0 1 1 1 0 GMP synthase C terminal domain DUF4345 PF14248.6 ABK76168.1 - 7.3e-24 84.0 14.5 7.9e-24 83.8 14.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4345) TraT PF05818.12 ABK76168.1 - 0.12 12.0 0.9 0.16 11.6 0.9 1.1 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF4781 PF16013.5 ABK76168.1 - 0.34 9.7 2.6 0.48 9.2 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) DUF308 PF03729.13 ABK76168.1 - 0.37 11.2 10.6 1.2e+02 3.1 10.6 2.4 1 1 0 1 1 1 0 Short repeat of unknown function (DUF308) Amidohydro_1 PF01979.20 ABK76169.1 - 1.2e-67 228.7 2.7 1.6e-67 228.2 2.7 1.1 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 ABK76169.1 - 3.5e-53 179.0 0.5 6.9e-53 178.1 0.5 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Amidohydro_3 PF07969.11 ABK76169.1 - 1.6e-08 34.5 6.4 1.3e-07 31.5 2.3 2.4 1 1 1 2 2 2 2 Amidohydrolase family Ribosomal_S13 PF00416.22 ABK76170.1 - 1e-36 126.1 6.9 6.5e-35 120.3 6.9 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 ABK76170.1 - 0.022 13.5 0.0 0.024 13.4 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) H2TH PF06831.14 ABK76170.1 - 0.073 13.1 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Formamidopyrimidine-DNA glycosylase H2TH domain FAD_binding_3 PF01494.19 ABK76171.1 - 2.2e-19 69.9 0.7 2.8e-19 69.6 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ABK76171.1 - 6.6e-07 29.5 2.0 2.3e-06 27.7 2.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ABK76171.1 - 2.7e-06 27.2 3.0 2.7e-06 27.2 3.0 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 ABK76171.1 - 0.00053 19.4 1.8 0.024 13.9 0.3 2.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 ABK76171.1 - 0.00081 18.6 3.5 0.0015 17.7 3.5 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 ABK76171.1 - 0.0013 17.8 0.7 0.0025 16.9 0.7 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 ABK76171.1 - 0.0063 15.8 2.3 0.012 14.9 0.4 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ABK76171.1 - 0.027 15.0 0.4 0.027 15.0 0.4 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ABK76171.1 - 0.042 12.7 0.4 0.076 11.9 0.4 1.4 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 ABK76171.1 - 0.16 12.0 2.7 5.7 6.9 0.4 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 ABK76171.1 - 0.17 11.1 0.2 0.28 10.4 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ABK76171.1 - 0.18 11.1 3.0 1.3 8.3 1.3 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 ABK76171.1 - 0.21 10.8 2.5 0.39 10.0 2.5 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 ABK76171.1 - 0.32 9.6 1.1 0.43 9.2 1.1 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 ABK76171.1 - 0.9 8.6 2.5 1.2 8.1 2.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF883 PF05957.13 ABK76172.1 - 3e-05 24.5 11.8 8.2e-05 23.1 11.8 1.8 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 ABK76172.1 - 3.2e-05 23.9 7.1 5.1e-05 23.2 7.1 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 ABK76172.1 - 0.31 11.1 3.7 0.55 10.3 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Prominin PF05478.11 ABK76172.1 - 1.2 7.0 4.5 1.6 6.6 4.5 1.1 1 0 0 1 1 1 0 Prominin Vps53_N PF04100.12 ABK76172.1 - 3.1 6.7 7.6 4.4 6.2 7.6 1.1 1 0 0 1 1 1 0 Vps53-like, N-terminal ATP-synt_B PF00430.18 ABK76172.1 - 8.7 6.4 18.7 19 5.4 18.7 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Putative_PNPOx PF01243.20 ABK76173.1 - 2.2e-14 53.4 0.2 1.6e-13 50.6 0.2 2.1 2 1 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Lyx_isomer PF07385.12 ABK76173.1 - 0.16 11.2 0.0 0.3 10.3 0.0 1.4 1 1 0 1 1 1 0 D-lyxose isomerase MFS_1 PF07690.16 ABK76174.1 - 1e-54 185.8 28.5 1e-54 185.8 28.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ABK76174.1 - 0.039 13.3 30.3 4.1 6.6 30.3 2.1 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB Phage_holin_3_6 PF07332.11 ABK76174.1 - 0.069 13.2 0.1 0.069 13.2 0.1 4.7 4 2 1 5 5 5 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4131 PF13567.6 ABK76174.1 - 0.78 9.4 0.0 0.78 9.4 0.0 4.0 4 2 1 5 5 5 0 Domain of unknown function (DUF4131) OATP PF03137.20 ABK76174.1 - 2.4 6.3 5.3 4.7 5.4 0.1 2.5 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family RecX PF02631.16 ABK76176.1 - 2.1e-28 99.3 0.4 2.1e-28 99.3 0.4 1.7 1 1 1 2 2 2 2 RecX family DUF4543 PF15076.6 ABK76176.1 - 0.11 12.7 1.3 5.7 7.2 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4543) CTP_synth_N PF06418.14 ABK76177.1 - 2.2e-121 404.2 0.0 2.9e-121 403.8 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 ABK76177.1 - 3.3e-45 154.2 0.0 4.8e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ABK76177.1 - 3.4e-07 30.2 0.2 3e-06 27.1 0.1 2.4 2 1 0 2 2 2 1 Peptidase C26 CbiA PF01656.23 ABK76177.1 - 0.046 13.8 0.0 0.071 13.2 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain KH_2 PF07650.17 ABK76178.1 - 3.2e-21 74.9 0.5 6.1e-21 74.0 0.5 1.5 1 0 0 1 1 1 1 KH domain MMR_HSR1 PF01926.23 ABK76178.1 - 2.4e-20 72.7 0.1 5.1e-20 71.7 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ABK76178.1 - 5e-10 39.1 0.1 2.2e-09 37.0 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 ABK76178.1 - 6.3e-08 32.9 0.2 7.2e-05 22.9 0.1 2.3 1 1 1 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 ABK76178.1 - 9e-08 32.2 0.1 9.7e-06 25.6 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 ABK76178.1 - 2.8e-07 30.4 0.0 1e-06 28.6 0.0 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 ABK76178.1 - 9e-06 25.4 0.1 0.0041 16.7 0.1 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 ABK76178.1 - 6.1e-05 22.4 0.0 0.0001 21.7 0.0 1.3 1 0 0 1 1 1 1 AIG1 family AAA_22 PF13401.6 ABK76178.1 - 0.0008 19.7 0.0 0.021 15.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.10 ABK76178.1 - 0.0076 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 ABK76178.1 - 0.12 12.6 0.0 0.62 10.3 0.0 2.0 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 ABK76178.1 - 0.15 12.4 0.0 0.58 10.6 0.0 1.9 2 0 0 2 2 2 0 RNA helicase cobW PF02492.19 ABK76178.1 - 0.16 11.6 0.2 1.4 8.5 0.0 2.3 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 ABK76178.1 - 0.24 11.1 0.0 0.37 10.5 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Zn_Tnp_IS1595 PF12760.7 ABK76179.1 - 0.43 10.6 11.5 0.75 9.8 7.3 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-FCS PF06467.14 ABK76179.1 - 2 8.4 9.1 2.4 8.2 0.0 2.9 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif EamA PF00892.20 ABK76180.1 - 1.7e-10 41.2 42.3 3.5e-10 40.2 14.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family CoA_transf_3 PF02515.17 ABK76181.1 - 1e-105 353.9 0.2 1.2e-105 353.7 0.2 1.0 1 0 0 1 1 1 1 CoA-transferase family III DUF1127 PF06568.11 ABK76181.1 - 0.0015 18.2 0.2 0.0015 18.2 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1127) G_glu_transpept PF01019.21 ABK76182.1 - 1.5e-92 311.1 0.1 1.7e-92 310.9 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Cons_hypoth95 PF03602.15 ABK76183.1 - 8.4e-43 146.1 0.0 9.3e-43 146.0 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 ABK76183.1 - 1.4e-06 28.0 0.0 1.7e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain RsmJ PF04378.13 ABK76183.1 - 0.0022 17.3 0.0 0.0027 17.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA large subunit methyltransferase D, RlmJ PrmA PF06325.13 ABK76183.1 - 0.0025 17.3 0.5 0.0028 17.1 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_24 PF13578.6 ABK76183.1 - 0.0033 18.4 0.2 0.0047 17.9 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 ABK76183.1 - 0.15 11.8 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_31 PF13847.6 ABK76183.1 - 0.16 11.8 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain N6_N4_Mtase PF01555.18 ABK76183.1 - 0.26 11.0 0.0 8.9 5.9 0.0 2.1 2 0 0 2 2 2 0 DNA methylase DUF3073 PF11273.8 ABK76185.1 - 3.9e-23 81.9 1.6 4.3e-23 81.8 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3073) GntR PF00392.21 ABK76186.1 - 4e-19 68.0 0.2 1.2e-18 66.5 0.2 1.9 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Aminotran_1_2 PF00155.21 ABK76186.1 - 8.5e-18 64.7 0.0 1.2e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Rrf2 PF02082.20 ABK76186.1 - 0.045 14.1 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator HTH_Crp_2 PF13545.6 ABK76186.1 - 0.11 12.5 0.1 0.27 11.2 0.1 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_36 PF13730.6 ABK76186.1 - 0.12 12.3 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Mycobact_memb PF05423.13 ABK76187.1 - 2.1e-44 150.8 0.0 2.4e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 Mycobacterium membrane protein YjbE PF11106.8 ABK76187.1 - 0.015 15.5 0.1 0.028 14.6 0.1 1.4 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE SpoIIE PF07228.12 ABK76188.1 - 1.7e-32 112.9 0.0 2.6e-32 112.3 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Response_reg PF00072.24 ABK76188.1 - 5.2e-17 62.0 0.1 8.1e-17 61.4 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain AAA_lid_2 PF17863.1 ABK76188.1 - 0.054 13.3 0.4 0.18 11.7 0.1 2.0 2 0 0 2 2 2 0 AAA lid domain DUF218 PF02698.17 ABK76189.1 - 1.1e-23 83.7 0.0 1.5e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 DUF218 domain Lactamase_B_3 PF13483.6 ABK76191.1 - 3.9e-08 33.4 0.0 8e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Rieske PF00355.26 ABK76191.1 - 4.7e-08 32.8 0.5 9.6e-08 31.9 0.5 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Lactamase_B_2 PF12706.7 ABK76191.1 - 2.8e-05 23.7 0.3 5e-05 22.9 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain ABC2_membrane PF01061.24 ABK76192.1 - 4.2e-25 88.4 12.6 7.2e-25 87.6 10.9 1.8 2 0 0 2 2 2 1 ABC-2 type transporter NAD_binding_2 PF03446.15 ABK76193.1 - 8.1e-40 136.6 0.7 1.1e-39 136.1 0.7 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ABK76193.1 - 1.6e-14 54.2 1.1 6e-14 52.3 0.1 2.3 2 1 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 ABK76193.1 - 0.00036 19.9 0.0 0.00061 19.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 ABK76193.1 - 0.0037 16.9 0.0 0.032 13.8 0.0 2.1 1 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 ABK76193.1 - 0.031 14.9 2.1 0.15 12.7 2.1 2.1 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 ABK76193.1 - 0.055 13.0 0.4 0.16 11.5 0.1 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Acetyltransf_1 PF00583.25 ABK76194.1 - 2.3e-12 47.2 0.0 3e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ABK76194.1 - 7.9e-09 35.5 0.0 1.1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ABK76194.1 - 1.7e-07 31.6 0.0 2.4e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 ABK76194.1 - 6.9e-05 22.7 0.1 0.00019 21.4 0.1 1.7 2 0 0 2 2 2 1 ESCO1/2 acetyl-transferase FR47 PF08445.10 ABK76194.1 - 9.9e-05 22.2 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_6 PF13480.7 ABK76194.1 - 0.003 17.7 0.4 0.0043 17.2 0.4 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ABK76194.1 - 0.0034 17.5 0.1 0.005 16.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ABK76194.1 - 0.0077 16.3 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase RecG_wedge PF17191.4 ABK76195.1 - 2.5e-05 24.0 0.0 3.1e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 RecG wedge domain tRNA_anti-codon PF01336.25 ABK76195.1 - 0.004 17.1 0.1 0.0056 16.7 0.1 1.2 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain CBS PF00571.28 ABK76197.1 - 2.1e-20 72.9 3.8 3.3e-11 43.5 1.3 2.1 2 0 0 2 2 2 2 CBS domain GT87 PF09594.10 ABK76198.1 - 4.6e-15 56.0 33.1 4.6e-15 56.0 33.1 2.7 2 1 1 3 3 3 1 Glycosyltransferase family 87 PIG-U PF06728.13 ABK76198.1 - 0.00042 19.5 0.4 0.00042 19.5 0.4 1.9 2 1 0 2 2 2 1 GPI transamidase subunit PIG-U Mannosyl_trans PF05007.13 ABK76198.1 - 0.0019 18.1 13.3 0.028 14.3 0.0 3.4 3 1 1 4 4 4 2 Mannosyltransferase (PIG-M) GFO_IDH_MocA PF01408.22 ABK76199.1 - 2.2e-10 41.4 0.2 6.6e-10 39.9 0.1 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ABK76199.1 - 0.006 16.6 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain T2SSF PF00482.23 ABK76200.1 - 5.3e-11 42.6 0.8 5.3e-11 42.6 0.8 1.6 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein F UbiA PF01040.18 ABK76200.1 - 0.0053 16.1 2.9 0.0087 15.4 2.9 1.4 1 0 0 1 1 1 1 UbiA prenyltransferase family Sigma70_r2 PF04542.14 ABK76201.1 - 1.8e-11 43.6 0.0 3.3e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 ABK76201.1 - 2e-10 40.1 0.2 3.3e-10 39.5 0.2 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 ABK76201.1 - 7.8e-05 22.1 0.1 0.00013 21.4 0.1 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 ABK76201.1 - 0.012 15.5 0.1 0.025 14.4 0.1 1.6 1 1 0 1 1 1 0 ECF sigma factor DHFR_1 PF00186.19 ABK76202.1 - 2.3e-44 150.9 0.0 3e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrofolate reductase ATP-grasp_5 PF13549.6 ABK76203.1 - 1.8e-58 197.6 0.1 3.1e-58 196.9 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 ABK76203.1 - 1.6e-42 144.6 1.8 1.6e-42 144.6 1.8 2.1 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 ABK76203.1 - 8.6e-19 68.1 0.1 2.8e-18 66.5 0.1 2.0 2 0 0 2 2 2 1 CoA binding domain CoA_binding PF02629.19 ABK76203.1 - 1.9e-07 31.7 0.2 1.4e-06 28.8 0.0 2.5 2 0 0 2 2 2 1 CoA binding domain ATP-grasp_2 PF08442.10 ABK76203.1 - 0.0029 17.2 0.0 0.026 14.1 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 ABK76203.1 - 0.062 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Gln-synt_C PF00120.24 ABK76204.1 - 6.3e-128 426.6 0.0 7.4e-128 426.4 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 ABK76204.1 - 4.2e-26 90.5 0.0 9.3e-26 89.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Gln-synt_N_2 PF16952.5 ABK76204.1 - 0.072 12.9 0.0 0.53 10.1 0.0 2.1 1 1 0 1 1 1 0 Glutamine synthetase N-terminal domain SOUL PF04832.12 ABK76206.1 - 5e-21 75.6 0.0 6.3e-16 59.0 0.0 2.0 1 1 1 2 2 2 2 SOUL heme-binding protein Polyketide_cyc2 PF10604.9 ABK76207.1 - 4.9e-16 59.3 0.0 6.2e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 ABK76207.1 - 2.8e-08 34.0 0.0 5.3e-08 33.1 0.0 1.5 1 1 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc PF03364.20 ABK76207.1 - 7.1e-08 32.7 0.2 1.1e-07 32.1 0.2 1.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport START PF01852.19 ABK76207.1 - 0.067 12.6 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 START domain Lsr2 PF11774.8 ABK76208.1 - 2.7e-43 146.6 1.6 3e-43 146.4 1.6 1.0 1 0 0 1 1 1 1 Lsr2 Pou PF00157.17 ABK76208.1 - 0.013 15.4 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain Phage_cap_E PF03864.15 ABK76208.1 - 0.041 13.1 0.1 0.042 13.0 0.1 1.2 1 0 0 1 1 1 0 Phage major capsid protein E MM_CoA_mutase PF01642.22 ABK76209.1 - 5.1e-197 655.5 0.0 5.7e-197 655.3 0.0 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase CoA_transf_3 PF02515.17 ABK76210.1 - 1.5e-117 392.8 0.2 1.7e-117 392.6 0.2 1.0 1 0 0 1 1 1 1 CoA-transferase family III Glyco_hydro_42C PF08533.10 ABK76210.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase C-terminal domain Glycos_transf_2 PF00535.26 ABK76211.1 - 5.5e-22 78.4 0.0 7.5e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 GtrA PF04138.14 ABK76211.1 - 8.7e-11 42.1 9.6 5.4e-10 39.5 10.2 1.9 1 1 1 2 2 2 2 GtrA-like protein Glyco_tranf_2_3 PF13641.6 ABK76211.1 - 0.00063 19.7 0.1 0.001 19.0 0.1 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Polysacc_synt_C PF14667.6 ABK76211.1 - 2.1 8.4 10.4 3.5 7.7 10.4 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain EspB_PE PF18625.1 ABK76212.1 - 7.7e-20 71.1 3.2 7.7e-20 71.1 3.2 2.4 2 1 1 3 3 3 1 ESX-1 secreted protein B PE domain PPE PF00823.19 ABK76212.1 - 0.0012 18.9 1.6 0.0012 18.9 1.6 2.5 2 1 0 2 2 2 1 PPE family Big_10 PF17964.1 ABK76213.1 - 1.1e-20 74.4 0.2 1.9e-20 73.6 0.2 1.3 1 0 0 1 1 1 1 Bacterial Ig domain YkuD PF03734.14 ABK76213.1 - 6.9e-13 49.2 0.1 1.3e-12 48.4 0.1 1.4 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain DUF2778 PF10908.8 ABK76213.1 - 0.22 11.8 0.0 0.5 10.7 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2778) FCD PF07729.12 ABK76215.1 - 1.7e-27 96.3 3.9 1.7e-27 96.3 3.9 1.7 2 1 0 2 2 2 1 FCD domain GntR PF00392.21 ABK76215.1 - 2e-16 59.4 0.1 4.7e-16 58.2 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family MarR_2 PF12802.7 ABK76215.1 - 0.00018 21.3 0.1 0.00058 19.7 0.1 1.9 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.20 ABK76215.1 - 0.00026 21.3 0.0 0.00061 20.1 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator HTH_Crp_2 PF13545.6 ABK76215.1 - 0.0078 16.2 0.3 0.13 12.2 0.1 2.4 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_41 PF14502.6 ABK76215.1 - 0.014 15.1 0.0 0.029 14.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain TrmB PF01978.19 ABK76215.1 - 0.056 13.3 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.20 ABK76215.1 - 0.081 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Fe_dep_repress PF01325.19 ABK76215.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_28 PF13518.6 ABK76215.1 - 0.14 12.3 0.6 0.6 10.3 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain V-SNARE PF05008.15 ABK76215.1 - 0.16 12.4 0.1 0.36 11.2 0.1 1.6 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus FUSC PF04632.12 ABK76215.1 - 1.1 7.7 10.8 0.099 11.2 2.9 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family Pribosyltran PF00156.27 ABK76216.1 - 0.00012 21.6 0.2 0.00015 21.4 0.2 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 ABK76216.1 - 0.0011 18.6 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase zf-NADH-PPase PF09297.11 ABK76216.1 - 0.014 15.1 4.4 0.023 14.3 0.1 2.6 1 1 1 2 2 2 0 NADH pyrophosphatase zinc ribbon domain UPRTase PF14681.6 ABK76216.1 - 0.028 13.9 0.1 0.046 13.2 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase APH PF01636.23 ABK76218.1 - 4.9e-25 88.8 2.2 6e-25 88.5 2.2 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 ABK76218.1 - 0.00037 19.9 0.0 0.00054 19.4 0.0 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 ABK76218.1 - 0.00074 18.5 0.0 0.00096 18.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) DUF1851 PF08906.11 ABK76219.1 - 0.013 15.5 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1851) HTH_30 PF13556.6 ABK76220.1 - 1.8e-22 78.8 1.9 4.1e-21 74.5 3.0 2.5 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain PucR PF07905.11 ABK76220.1 - 2.6e-17 63.2 0.2 4.3e-16 59.3 0.0 2.5 3 0 0 3 3 3 1 Purine catabolism regulatory protein-like family GGDEF_2 PF17853.1 ABK76220.1 - 4.9e-11 42.9 0.9 4.9e-11 42.9 0.9 3.2 3 1 0 3 3 3 1 GGDEF-like domain OmpA PF00691.20 ABK76220.1 - 0.073 13.5 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 OmpA family Ald_Xan_dh_C2 PF02738.18 ABK76221.1 - 5.2e-125 418.0 0.1 7.5e-125 417.5 0.1 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 ABK76221.1 - 7.9e-13 48.7 7.0 2e-11 44.2 7.0 2.5 1 1 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fe-ADH PF00465.19 ABK76222.1 - 5.4e-67 226.2 10.6 6.2e-67 226.0 10.6 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 ABK76222.1 - 4.8e-12 46.1 1.2 6.2e-12 45.8 1.2 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Bac_DnaA PF00308.18 ABK76223.1 - 9.3e-104 346.0 0.1 2.5e-103 344.6 0.0 1.7 2 0 0 2 2 2 1 Bacterial dnaA protein Bac_DnaA_C PF08299.11 ABK76223.1 - 5.2e-27 93.7 0.0 1e-26 92.8 0.0 1.5 1 0 0 1 1 1 1 Bacterial dnaA protein helix-turn-helix IstB_IS21 PF01695.17 ABK76223.1 - 1.6e-10 41.0 0.0 2.8e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA PF00004.29 ABK76223.1 - 1.5e-05 25.5 0.0 7.3e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ABK76223.1 - 0.0019 18.5 0.3 1.4 9.2 0.0 2.7 1 1 1 2 2 2 2 AAA domain DnaA_N PF11638.8 ABK76223.1 - 0.0099 15.6 0.0 0.05 13.4 0.0 2.2 2 0 0 2 2 2 1 DnaA N-terminal domain AFG1_ATPase PF03969.16 ABK76223.1 - 0.029 13.3 0.0 0.46 9.3 0.0 2.1 1 1 1 2 2 2 0 AFG1-like ATPase AAA_16 PF13191.6 ABK76223.1 - 0.036 14.5 0.2 0.16 12.4 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 ABK76223.1 - 0.049 14.0 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 ABK76223.1 - 0.05 13.5 0.0 0.19 11.6 0.0 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea HTH_38 PF13936.6 ABK76223.1 - 0.083 12.7 0.0 0.3 10.9 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain Polyketide_cyc2 PF10604.9 ABK76224.1 - 5.3e-20 72.2 1.0 6e-20 72.0 1.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 ABK76224.1 - 0.06 13.6 0.3 0.13 12.4 0.3 1.6 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 ABK76224.1 - 0.076 13.3 0.3 0.093 13.0 0.3 1.2 1 0 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein ADH_zinc_N PF00107.26 ABK76225.1 - 1.3e-12 47.8 0.1 2.8e-12 46.8 0.1 1.6 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ABK76225.1 - 3.5e-12 46.2 0.0 1.3e-11 44.3 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ABK76225.1 - 6.5e-09 36.9 0.0 2e-08 35.4 0.0 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 ABK76225.1 - 0.0061 16.5 0.7 0.0093 15.9 0.7 1.3 1 0 0 1 1 1 1 NAD(P)H-binding HD_4 PF13328.6 ABK76226.1 - 9.1e-06 25.5 0.2 1.6e-05 24.7 0.2 1.5 1 0 0 1 1 1 1 HD domain HD PF01966.22 ABK76226.1 - 0.0032 17.7 1.0 0.0041 17.3 1.0 1.4 1 1 0 1 1 1 1 HD domain adh_short PF00106.25 ABK76228.1 - 2.1e-35 122.0 0.0 3e-35 121.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ABK76228.1 - 1.7e-19 70.4 0.0 2.5e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ABK76228.1 - 3.8e-11 43.2 0.0 6.7e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Glyco_transf_4 PF13439.6 ABK76228.1 - 0.016 15.2 0.2 0.89 9.5 0.1 2.8 3 0 0 3 3 3 0 Glycosyltransferase Family 4 Epimerase PF01370.21 ABK76228.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyco_trans_4_4 PF13579.6 ABK76228.1 - 0.36 11.2 4.6 2.1 8.8 4.6 2.4 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain PRiA4_ORF3 PF07929.11 ABK76229.1 - 2.1e-51 174.1 0.0 2.5e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein ECH_1 PF00378.20 ABK76231.1 - 4.2e-21 75.4 0.1 4.9e-21 75.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ABK76231.1 - 4.5e-07 29.7 0.5 5.2e-07 29.5 0.5 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase MFS_1 PF07690.16 ABK76232.1 - 1.5e-30 106.3 77.5 1.6e-25 89.8 45.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ABK76232.1 - 1e-05 25.0 39.8 1.8e-05 24.2 39.7 1.5 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Nuc_H_symport PF03825.16 ABK76232.1 - 0.0029 16.6 25.7 0.1 11.5 7.9 3.4 2 2 0 3 3 3 3 Nucleoside H+ symporter MFS_1_like PF12832.7 ABK76232.1 - 0.054 12.3 16.0 0.21 10.4 11.4 3.0 2 1 1 3 3 3 0 MFS_1 like family Amidohydro_1 PF01979.20 ABK76233.1 - 3.3e-35 122.0 0.4 3.9e-35 121.8 0.4 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ABK76233.1 - 3e-10 40.2 8.5 4.3e-10 39.7 3.2 2.4 2 1 0 2 2 2 2 Amidohydrolase family DNA_topoisoIV PF00521.20 ABK76234.1 - 7.4e-117 390.8 0.0 8.9e-117 390.6 0.0 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 ABK76234.1 - 8e-10 38.1 0.1 3.1e-06 26.6 0.0 2.6 2 0 0 2 2 2 2 DNA gyrase C-terminal domain, beta-propeller Gln-synt_C PF00120.24 ABK76235.1 - 8.3e-84 281.5 0.0 9.9e-84 281.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 ABK76235.1 - 0.0058 16.5 0.0 0.022 14.6 0.0 1.9 1 1 0 1 1 1 1 Glutamine synthetase N-terminal domain Gln-synt_N PF03951.19 ABK76235.1 - 0.014 15.1 0.2 0.17 11.6 0.1 2.3 2 0 0 2 2 2 0 Glutamine synthetase, beta-Grasp domain Bac_luciferase PF00296.20 ABK76236.1 - 4.8e-27 95.2 2.1 2.3e-26 93.0 2.1 1.8 1 1 0 1 1 1 1 Luciferase-like monooxygenase DUF1404 PF07185.11 ABK76237.1 - 0.087 12.5 3.4 0.068 12.9 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1404) DUF2339 PF10101.9 ABK76237.1 - 0.25 9.9 60.1 0.36 9.4 60.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) UPF0139 PF03669.13 ABK76237.1 - 7.2 6.6 8.4 14 5.6 1.7 3.7 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0139) Cupin_2 PF07883.11 ABK76238.1 - 1.8e-07 30.7 0.0 3.3e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 ABK76238.1 - 0.0065 16.1 0.0 0.0079 15.8 0.0 1.2 1 0 0 1 1 1 1 Cupin Auxin_BP PF02041.16 ABK76238.1 - 0.075 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Auxin binding protein HydF_dimer PF18128.1 ABK76238.1 - 0.17 12.0 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Hydrogen maturase F dimerization domain FAD_binding_3 PF01494.19 ABK76239.1 - 3.1e-62 210.8 0.0 6e-62 209.9 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 ABK76239.1 - 1.8e-06 27.8 2.8 0.032 13.8 0.1 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 ABK76239.1 - 2.2e-06 26.6 0.0 0.021 13.5 0.0 2.4 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 ABK76239.1 - 9.6e-05 21.8 0.0 0.029 13.6 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ABK76239.1 - 0.00075 20.0 0.0 0.19 12.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ABK76239.1 - 0.0031 17.7 0.1 0.012 15.8 0.0 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ABK76239.1 - 0.0064 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 ABK76239.1 - 0.016 14.3 0.2 0.028 13.5 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.16 ABK76239.1 - 0.052 13.2 0.1 0.088 12.5 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 ABK76239.1 - 0.079 12.2 0.2 0.12 11.6 0.2 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF992 PF06186.11 ABK76239.1 - 0.14 12.0 0.1 0.29 11.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF992) # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Mycobacterium_smegmatis_str._MC2_155-ASM1500v1/GCA_000015005.1_ASM1500v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Mycobacterium_smegmatis_str._MC2_155-ASM1500v1/GCA_000015005.1_ASM1500v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Mycobacterium_smegmatis_str._MC2_155-ASM1500v1/GCA_000015005.1_ASM1500v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Mycobacterium_smegmatis_str._MC2_155-ASM1500v1/GCA_000015005.1_ASM1500v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 03:47:49 2019 # [ok]