# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DUF1013 PF06242.11 ETZ06676.1 - 9.1e-38 129.4 0.2 1.5e-37 128.7 0.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1013) Aminotran_1_2 PF00155.21 ETZ06677.1 - 2e-49 168.7 0.0 2.3e-49 168.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 ETZ06677.1 - 0.0011 17.6 0.0 0.0018 16.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme BATS PF06968.13 ETZ06678.1 - 8.1e-20 70.8 0.0 3.2e-19 68.9 0.0 1.9 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 ETZ06678.1 - 2.8e-15 57.1 0.0 4.3e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Peptidase_M23 PF01551.22 ETZ06679.1 - 1.4e-32 111.7 1.0 2.7e-32 110.8 1.0 1.5 1 0 0 1 1 1 1 Peptidase family M23 Nup188 PF10487.9 ETZ06679.1 - 0.037 12.0 0.2 0.051 11.5 0.2 1.1 1 0 0 1 1 1 0 Nucleoporin subcomplex protein binding to Pom34 PseudoU_synth_1 PF01416.20 ETZ06680.1 - 1.7e-28 99.2 0.1 7.3e-20 71.5 0.0 2.1 2 0 0 2 2 2 2 tRNA pseudouridine synthase Ribosomal_S3Ae PF01015.18 ETZ06680.1 - 0.057 13.0 0.0 0.084 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal S3Ae family CDC14 PF08045.11 ETZ06681.1 - 0.031 13.4 0.0 0.033 13.3 0.0 1.0 1 0 0 1 1 1 0 Cell division control protein 14, SIN component LptC PF06835.13 ETZ06682.1 - 0.00057 19.5 0.0 0.00074 19.1 0.0 1.2 1 1 0 1 1 1 1 Lipopolysaccharide-assembly, LptC-related DNA_pol_A PF00476.20 ETZ06683.1 - 5.5e-124 414.0 0.1 7.8e-124 413.5 0.1 1.1 1 0 0 1 1 1 1 DNA polymerase family A 5_3_exonuc_N PF02739.16 ETZ06683.1 - 2.9e-40 137.8 0.0 5.7e-40 136.8 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 ETZ06683.1 - 7.3e-21 74.6 0.0 5.7e-20 71.7 0.0 2.6 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold CPSase_L_D2 PF02786.17 ETZ06684.1 - 4.5e-67 225.6 0.0 6.7e-67 225.1 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ETZ06684.1 - 5.2e-44 149.3 0.1 1.4e-43 148.0 0.1 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ETZ06684.1 - 9.3e-38 128.6 0.0 2.6e-37 127.2 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 ETZ06684.1 - 9e-09 35.2 0.0 1.9e-08 34.1 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 ETZ06684.1 - 4.5e-07 29.6 0.0 1.2e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 ETZ06684.1 - 0.00037 20.6 0.0 0.0007 19.7 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 ETZ06684.1 - 0.0071 16.1 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Acyltransferase PF01553.21 ETZ06685.1 - 4.2e-19 68.5 0.1 7.7e-19 67.7 0.1 1.4 1 1 0 1 1 1 1 Acyltransferase MMR_HSR1 PF01926.23 ETZ06686.1 - 2.6e-22 79.1 0.1 4.7e-22 78.2 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ETZ06686.1 - 5e-11 42.4 0.1 9e-11 41.5 0.1 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 ETZ06686.1 - 4.7e-10 39.6 0.5 0.00084 19.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 ETZ06686.1 - 3.2e-09 37.1 2.0 3.7e-05 23.9 0.2 2.3 1 1 1 2 2 2 2 Dynamin family KH_2 PF07650.17 ETZ06686.1 - 1.9e-08 34.0 0.7 5.2e-08 32.6 0.1 2.0 2 0 0 2 2 2 1 KH domain GTP_EFTU PF00009.27 ETZ06686.1 - 2.1e-07 30.7 0.1 6.3e-05 22.6 0.0 2.3 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain cobW PF02492.19 ETZ06686.1 - 2.3e-06 27.3 0.2 0.00028 20.5 0.0 2.1 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 ETZ06686.1 - 0.0015 18.4 0.1 0.027 14.3 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AIG1 PF04548.16 ETZ06686.1 - 0.0035 16.7 0.0 0.0057 16.0 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Roc PF08477.13 ETZ06686.1 - 0.0089 16.2 3.2 0.25 11.6 0.0 2.4 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 ETZ06686.1 - 0.014 14.8 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 ETZ06686.1 - 0.015 14.8 0.0 0.034 13.5 0.0 1.6 1 1 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 ETZ06686.1 - 0.016 15.4 0.0 0.048 13.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ETZ06686.1 - 0.021 15.4 0.0 0.043 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 ETZ06686.1 - 0.028 13.8 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_33 PF13671.6 ETZ06686.1 - 0.06 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 ETZ06686.1 - 0.077 12.3 0.2 0.16 11.3 0.0 1.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_16 PF13191.6 ETZ06686.1 - 0.1 13.0 0.0 0.18 12.1 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 ETZ06686.1 - 0.13 12.6 0.1 0.39 10.9 0.0 2.0 2 1 0 2 2 1 0 AAA domain ABC_tran PF00005.27 ETZ06686.1 - 0.18 12.3 0.7 0.29 11.7 0.1 1.7 2 1 0 2 2 1 0 ABC transporter Ribonucleas_3_3 PF14622.6 ETZ06687.1 - 1.8e-17 63.7 0.0 2.8e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 ETZ06687.1 - 1.7e-14 54.3 0.1 2.6e-14 53.7 0.1 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 ETZ06687.1 - 4.1e-13 49.9 0.0 1.3e-12 48.2 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain DND1_DSRM PF14709.7 ETZ06687.1 - 2.2e-08 34.2 1.9 7.3e-08 32.6 1.3 2.2 2 1 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 ATP-synt_DE_N PF02823.16 ETZ06688.1 - 1.3e-07 31.4 0.0 1.6e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ATP-synt_ab PF00006.25 ETZ06689.1 - 2.6e-61 207.0 0.0 3.5e-61 206.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 ETZ06689.1 - 8e-19 67.9 0.7 1.7e-18 66.9 0.7 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 ETZ06689.1 - 0.011 15.1 0.9 0.13 11.6 0.2 2.4 2 0 0 2 2 2 0 KaiC ATPase_2 PF01637.18 ETZ06689.1 - 0.017 15.1 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 ETZ06689.1 - 0.054 12.7 0.4 0.11 11.6 0.1 1.6 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.29 ETZ06689.1 - 0.078 13.4 0.1 0.53 10.7 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 ETZ06689.1 - 0.093 12.6 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.6 ETZ06689.1 - 0.15 12.4 0.9 0.24 11.7 0.2 1.6 2 0 0 2 2 2 0 AAA domain DUF4096 PF13340.6 ETZ06690.1 - 0.00042 20.5 0.0 0.00048 20.3 0.0 1.1 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) eIF-1a PF01176.19 ETZ06691.1 - 6.1e-19 67.6 0.0 6.8e-19 67.4 0.0 1.0 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 RsgA_N PF16745.5 ETZ06691.1 - 0.0026 17.5 0.0 0.0036 17.0 0.0 1.3 1 0 0 1 1 1 1 RsgA N-terminal domain DUF4537 PF15057.6 ETZ06691.1 - 0.0075 16.3 0.0 0.009 16.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Peptidase_M99_m PF17130.4 ETZ06691.1 - 0.12 12.4 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 beta-barrel domain of carboxypeptidase M99 rve PF00665.26 ETZ06692.1 - 0.00052 20.2 0.0 0.00054 20.1 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain HTH_28 PF13518.6 ETZ06695.1 - 0.021 14.9 0.0 0.032 14.4 0.0 1.4 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 ETZ06695.1 - 0.024 14.4 0.2 0.056 13.3 0.2 1.7 1 1 0 1 1 1 0 Homeodomain-like domain BrkDBD PF09607.10 ETZ06695.1 - 0.045 13.5 0.6 0.081 12.7 0.2 1.6 1 1 0 1 1 1 0 Brinker DNA-binding domain HTH_29 PF13551.6 ETZ06695.1 - 0.084 12.9 0.0 0.25 11.4 0.0 1.6 1 1 1 2 2 2 0 Winged helix-turn helix zf-CHC2 PF01807.20 ETZ06696.1 - 1.3e-35 121.1 0.1 2.5e-35 120.2 0.1 1.5 1 0 0 1 1 1 1 CHC2 zinc finger Toprim_N PF08275.11 ETZ06696.1 - 6.6e-30 103.8 0.0 1.4e-29 102.8 0.0 1.6 1 0 0 1 1 1 1 DNA primase catalytic core, N-terminal domain Toprim_2 PF13155.6 ETZ06696.1 - 9.9e-10 38.7 0.0 2.7e-09 37.3 0.0 1.8 2 0 0 2 2 2 1 Toprim-like Toprim_4 PF13662.6 ETZ06696.1 - 4.6e-09 36.6 0.0 1.1e-08 35.5 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Toprim PF01751.22 ETZ06696.1 - 0.0062 16.7 0.0 0.017 15.3 0.0 1.8 1 0 0 1 1 1 1 Toprim domain Pyr_redox_2 PF07992.14 ETZ06697.1 - 5.4e-54 183.4 0.0 6.6e-54 183.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ETZ06697.1 - 8.2e-27 93.6 0.0 2.1e-26 92.4 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 ETZ06697.1 - 3.7e-18 65.8 1.6 1.8e-15 57.3 0.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETZ06697.1 - 9.1e-10 38.3 0.8 2.7e-09 36.7 0.8 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETZ06697.1 - 5.6e-09 36.1 0.4 0.0036 17.5 0.1 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 ETZ06697.1 - 6.3e-08 32.1 0.2 3.6e-06 26.3 0.1 2.6 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 ETZ06697.1 - 1.4e-05 24.6 0.1 3.4e-05 23.4 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ETZ06697.1 - 7.3e-05 21.6 9.2 0.0024 16.7 0.5 3.3 4 0 0 4 4 4 2 HI0933-like protein 2-Hacid_dh_C PF02826.19 ETZ06697.1 - 0.00099 18.5 0.1 0.025 13.9 0.0 2.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ETZ06697.1 - 0.0011 18.3 0.3 0.17 11.2 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 ETZ06697.1 - 0.0039 16.8 3.9 3.9 6.9 0.6 3.8 4 0 0 4 4 4 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ETZ06697.1 - 0.0052 15.9 9.6 0.012 14.7 1.2 3.0 3 1 1 4 4 4 2 FAD binding domain FAD_binding_3 PF01494.19 ETZ06697.1 - 0.0081 15.4 3.0 2.1 7.5 0.1 3.3 3 1 0 3 3 3 1 FAD binding domain 3HCDH_N PF02737.18 ETZ06697.1 - 0.064 13.1 1.0 0.65 9.9 0.0 2.6 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 ETZ06697.1 - 0.14 11.2 0.3 12 4.8 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Lip_A_acyltrans PF03279.13 ETZ06698.1 - 5.1e-40 137.5 1.0 6.1e-40 137.2 1.0 1.0 1 0 0 1 1 1 1 Bacterial lipid A biosynthesis acyltransferase Guanylate_cyc_2 PF09778.9 ETZ06698.1 - 0.083 12.2 2.7 0.54 9.6 0.5 2.2 1 1 1 2 2 2 0 Guanylylate cyclase Bac_GDH PF05088.12 ETZ06699.1 - 1.3e-200 669.3 0.2 2.9e-188 628.3 0.0 2.5 1 1 1 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog PF00208.21 ETZ06699.1 - 3.2e-08 33.6 0.1 1.3e-07 31.6 0.1 1.9 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase LpxC PF03331.13 ETZ06700.1 - 2.9e-72 243.4 0.0 3.3e-72 243.2 0.0 1.0 1 0 0 1 1 1 1 UDP-3-O-acyl N-acetylglycosamine deacetylase CN_hydrolase PF00795.22 ETZ06702.1 - 6.5e-19 68.3 0.0 1.3e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NTF-like PF14540.6 ETZ06702.1 - 0.053 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyltransferase-like LpxI_C PF06230.11 ETZ06703.1 - 1.6e-33 115.3 0.0 2.6e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 LpxI C-terminal domain LpxI_N PF17930.1 ETZ06703.1 - 1.1e-26 93.2 0.0 1.8e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 LpxI N-terminal domain DNA_pol3_chi PF04364.13 ETZ06705.1 - 2.3e-15 56.9 0.3 3.3e-15 56.4 0.3 1.2 1 0 0 1 1 1 1 DNA polymerase III chi subunit, HolC CTP_transf_1 PF01148.20 ETZ06706.1 - 2.1e-35 122.8 14.1 2.8e-35 122.4 14.1 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family YtpI PF14007.6 ETZ06706.1 - 0.029 14.5 3.4 0.63 10.2 0.6 2.5 2 0 0 2 2 2 0 YtpI-like protein DUF3360 PF11840.8 ETZ06706.1 - 0.044 12.5 7.4 0.033 12.9 6.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3360) DUF1129 PF06570.11 ETZ06706.1 - 2.5 7.5 8.9 0.51 9.8 4.2 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1129) DUF2085 PF09858.9 ETZ06706.1 - 7.7 7.1 10.8 9.7 6.7 4.7 2.9 1 1 2 3 3 3 0 Predicted membrane protein (DUF2085) DUF308 PF03729.13 ETZ06706.1 - 7.7 6.9 19.1 0.65 10.4 5.6 3.5 2 1 1 3 3 3 0 Short repeat of unknown function (DUF308) MafB19-deam PF14437.6 ETZ06707.1 - 2.5e-24 85.6 0.0 2.9e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 ETZ06707.1 - 9.4e-22 76.8 0.0 1.2e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region SNAD4 PF18750.1 ETZ06707.1 - 0.00036 20.6 0.1 0.00053 20.1 0.1 1.2 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 ETZ06707.1 - 0.014 15.4 0.1 0.02 14.9 0.1 1.1 1 0 0 1 1 1 0 APOBEC2 NAD1 PF18778.1 ETZ06707.1 - 0.017 15.2 0.1 0.024 14.8 0.1 1.1 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 NAD2 PF18782.1 ETZ06707.1 - 0.04 14.0 0.0 0.057 13.5 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 Bd3614-deam PF14439.6 ETZ06707.1 - 0.095 12.8 4.2 0.11 12.5 0.4 2.3 1 1 1 2 2 2 0 Bd3614-like deaminase Peptidase_A24 PF01478.18 ETZ06708.1 - 0.25 11.8 5.7 0.55 10.7 5.4 1.7 1 1 0 1 1 1 0 Type IV leader peptidase family DUF3576 PF12100.8 ETZ06709.1 - 2.8e-15 56.3 0.0 3.6e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3576) tRNA-synt_1 PF00133.22 ETZ06710.1 - 5e-63 213.3 1.7 2.2e-21 75.8 0.8 5.9 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 ETZ06710.1 - 1.1e-52 178.2 0.0 1.9e-52 177.5 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 ETZ06710.1 - 1.2e-30 106.6 0.3 9.8e-17 60.8 0.0 4.5 3 1 1 4 4 4 4 tRNA synthetases class I (M) Anticodon_1 PF08264.13 ETZ06710.1 - 5e-15 55.8 0.3 1.1e-14 54.6 0.3 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 ETZ06710.1 - 8.6e-09 35.2 0.0 0.003 16.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 ETZ06710.1 - 3e-07 29.7 0.0 0.0029 16.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (K) tRNA-synt_1d PF00750.19 ETZ06710.1 - 0.0058 15.6 0.0 0.0099 14.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) DNA_ligase_ZBD PF03119.16 ETZ06710.1 - 0.57 10.3 4.3 6.9 6.8 0.1 2.9 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain TRAF6_Z2 PF18048.1 ETZ06710.1 - 0.97 9.6 3.5 0.91 9.7 0.5 2.6 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 ABC_tran PF00005.27 ETZ06711.1 - 4.3e-45 153.6 1.0 8.8e-21 74.9 0.0 3.9 4 0 0 4 4 4 2 ABC transporter AAA_21 PF13304.6 ETZ06711.1 - 1.3e-13 51.4 16.1 0.0017 18.2 0.0 5.2 6 0 0 6 6 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ETZ06711.1 - 4.3e-11 42.7 0.5 0.04 13.4 0.2 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ETZ06711.1 - 2.1e-09 37.7 0.0 0.0032 17.7 0.0 3.0 2 1 0 2 2 2 2 AAA domain NACHT PF05729.12 ETZ06711.1 - 4.6e-08 33.1 0.3 0.019 14.9 0.0 3.1 3 0 0 3 3 3 2 NACHT domain Rad17 PF03215.15 ETZ06711.1 - 6.9e-08 32.6 0.2 0.0034 17.3 0.0 2.8 2 0 0 2 2 2 2 Rad17 P-loop domain AAA PF00004.29 ETZ06711.1 - 3.2e-07 30.8 0.0 0.036 14.5 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 ETZ06711.1 - 3.3e-07 30.4 0.2 0.033 14.1 0.0 2.7 3 0 0 3 3 2 2 RsgA GTPase AAA_29 PF13555.6 ETZ06711.1 - 5.9e-07 29.1 0.9 0.028 14.2 0.1 2.9 3 0 0 3 3 3 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ETZ06711.1 - 7.3e-07 29.3 0.0 0.028 14.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RNA_helicase PF00910.22 ETZ06711.1 - 3.3e-06 27.5 0.0 0.11 12.9 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.6 ETZ06711.1 - 1.1e-05 25.7 0.0 0.027 14.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ETZ06711.1 - 1.3e-05 25.6 0.1 0.25 11.7 0.0 3.1 3 1 0 3 3 3 2 AAA ATPase domain AAA_18 PF13238.6 ETZ06711.1 - 1.5e-05 25.6 0.1 0.25 11.9 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.6 ETZ06711.1 - 4.4e-05 23.4 12.7 0.0028 17.4 0.1 3.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 ETZ06711.1 - 7.4e-05 23.0 1.9 0.17 12.1 0.0 2.8 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.12 ETZ06711.1 - 0.00015 21.1 0.2 0.3 10.4 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin RuvB_N PF05496.12 ETZ06711.1 - 0.00016 21.4 0.1 0.52 10.1 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 ETZ06711.1 - 0.00021 21.3 0.8 0.14 12.2 0.0 2.8 3 0 0 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 ETZ06711.1 - 0.00024 20.4 0.5 0.25 10.5 0.0 2.8 3 0 0 3 3 2 2 Protein of unknown function (DUF815) AAA_23 PF13476.6 ETZ06711.1 - 0.00024 21.7 14.1 0.11 13.0 0.1 3.8 4 0 0 4 4 4 2 AAA domain AAA_7 PF12775.7 ETZ06711.1 - 0.00028 20.4 0.1 0.9 9.0 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 ETZ06711.1 - 0.0004 20.4 0.1 2.3 8.3 0.0 3.3 3 0 0 3 3 3 2 AAA domain ATP-synt_ab PF00006.25 ETZ06711.1 - 0.0005 19.8 0.1 1.1 8.9 0.0 2.2 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain ATPase_2 PF01637.18 ETZ06711.1 - 0.00052 20.0 1.2 0.95 9.3 0.0 3.2 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 ETZ06711.1 - 0.0006 19.1 0.0 0.63 9.2 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_24 PF13479.6 ETZ06711.1 - 0.00083 19.1 0.0 0.39 10.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 ETZ06711.1 - 0.0009 18.3 0.1 0.14 11.1 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 ETZ06711.1 - 0.00092 19.2 0.1 1.7 8.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 ETZ06711.1 - 0.001 18.8 0.3 0.66 9.7 0.1 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.6 ETZ06711.1 - 0.0015 18.9 0.0 1.9 8.9 0.0 3.1 2 1 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 ETZ06711.1 - 0.0017 17.6 0.0 1.3 8.1 0.0 2.6 2 0 0 2 2 2 2 KAP family P-loop domain Viral_helicase1 PF01443.18 ETZ06711.1 - 0.0018 18.1 0.2 1.4 8.6 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase dNK PF01712.19 ETZ06711.1 - 0.0019 18.1 0.2 0.78 9.6 0.0 2.5 2 0 0 2 2 2 1 Deoxynucleoside kinase AAA_25 PF13481.6 ETZ06711.1 - 0.0026 17.4 0.0 0.52 9.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 ETZ06711.1 - 0.0038 17.4 0.1 2.7 8.2 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 ETZ06711.1 - 0.008 16.3 0.9 6.2 6.8 0.0 3.4 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_30 PF13604.6 ETZ06711.1 - 0.012 15.4 0.0 3.3 7.4 0.0 2.6 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 ETZ06711.1 - 0.013 15.5 0.4 6.2 6.7 0.0 3.2 3 0 0 3 3 2 0 NTPase Cytidylate_kin PF02224.18 ETZ06711.1 - 0.015 15.0 0.0 6.9 6.3 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase Mg_chelatase PF01078.21 ETZ06711.1 - 0.03 13.7 0.0 2.3 7.5 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Septin PF00735.18 ETZ06711.1 - 0.032 13.5 0.0 2.8 7.1 0.0 2.5 2 0 0 2 2 2 0 Septin FeoB_N PF02421.18 ETZ06711.1 - 0.033 13.7 0.0 3.3 7.2 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Ploopntkinase3 PF18751.1 ETZ06711.1 - 0.043 13.7 0.1 13 5.7 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 IstB_IS21 PF01695.17 ETZ06711.1 - 0.063 13.0 0.3 4.8 6.9 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein MobB PF03205.14 ETZ06711.1 - 0.068 13.1 0.1 10 6.0 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PRK PF00485.18 ETZ06711.1 - 0.072 12.8 0.0 5.8 6.6 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ABC_tran_CTD PF16326.5 ETZ06711.1 - 0.1 12.9 5.4 0.41 10.9 5.4 2.1 1 1 0 1 1 1 0 ABC transporter C-terminal domain G-alpha PF00503.20 ETZ06711.1 - 0.16 11.1 4.7 1.8 7.6 0.1 2.8 3 1 0 3 3 2 0 G-protein alpha subunit Ras PF00071.22 ETZ06711.1 - 0.18 11.4 0.2 5.9 6.5 0.0 2.3 2 0 0 2 2 2 0 Ras family SRP54 PF00448.22 ETZ06711.1 - 0.2 11.2 0.1 8.6 5.9 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain K-box PF01486.17 ETZ06711.1 - 2.5 8.3 8.7 0.18 12.0 2.9 2.1 2 0 0 2 2 1 0 K-box region ABC_tran PF00005.27 ETZ06712.1 - 1.3e-32 113.2 0.0 2.7e-32 112.1 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 ETZ06712.1 - 7.3e-11 42.4 0.2 0.00015 21.7 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 ETZ06712.1 - 2.9e-05 23.9 0.0 0.017 14.8 0.0 2.2 2 0 0 2 2 2 2 IstB-like ATP binding protein RsgA_GTPase PF03193.16 ETZ06712.1 - 0.0011 18.9 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 ETZ06712.1 - 0.0024 17.3 0.0 0.18 11.2 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ETZ06712.1 - 0.0034 17.9 0.0 0.0048 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 ETZ06712.1 - 0.0068 15.6 0.0 0.0098 15.1 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_29 PF13555.6 ETZ06712.1 - 0.012 15.3 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 ETZ06712.1 - 0.024 15.0 0.1 0.038 14.4 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 ETZ06712.1 - 0.03 14.7 0.0 0.31 11.5 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ETZ06712.1 - 0.061 13.6 0.0 0.17 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 ETZ06712.1 - 0.061 13.4 0.0 0.14 12.3 0.0 1.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase DpnI_C PF17726.1 ETZ06712.1 - 0.13 12.4 0.1 0.28 11.3 0.1 1.6 1 0 0 1 1 1 0 Dam-replacing HTH domain Mg_chelatase PF01078.21 ETZ06712.1 - 0.18 11.2 0.0 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sua5_yciO_yrdC PF01300.18 ETZ06713.1 - 2e-42 144.7 0.1 2.6e-42 144.3 0.1 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 ETZ06713.1 - 9.1e-16 58.6 0.0 2.9e-15 57.0 0.0 1.8 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding AOX PF01786.17 ETZ06714.1 - 8.6e-60 202.0 0.0 1e-59 201.7 0.0 1.0 1 0 0 1 1 1 1 Alternative oxidase Ribonuc_red_sm PF00268.21 ETZ06715.1 - 6.1e-65 219.5 2.1 8.3e-65 219.0 2.1 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Ribonuc_red_lgC PF02867.15 ETZ06716.1 - 1.4e-105 353.9 0.0 3.4e-68 230.5 0.0 2.2 1 1 1 2 2 2 2 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 ETZ06716.1 - 6e-12 45.4 0.1 1.9e-11 43.8 0.1 1.9 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain Ribosomal_S20p PF01649.18 ETZ06717.1 - 1.4e-18 67.3 8.9 1.5e-18 67.2 8.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S20 Bac_DnaA PF00308.18 ETZ06718.1 - 5e-81 271.7 0.1 8.7e-81 270.9 0.1 1.4 1 0 0 1 1 1 1 Bacterial dnaA protein Bac_DnaA_C PF08299.11 ETZ06718.1 - 5.1e-28 96.9 0.0 1.1e-27 95.8 0.0 1.6 1 0 0 1 1 1 1 Bacterial dnaA protein helix-turn-helix DnaA_N PF11638.8 ETZ06718.1 - 1.4e-13 50.3 0.4 5.9e-13 48.4 0.1 2.2 2 0 0 2 2 2 1 DnaA N-terminal domain IstB_IS21 PF01695.17 ETZ06718.1 - 3.5e-10 39.9 0.2 2.1e-09 37.4 0.0 2.1 1 1 1 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 ETZ06718.1 - 1.8e-08 34.9 0.0 5.2e-07 30.1 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AFG1_ATPase PF03969.16 ETZ06718.1 - 8.5e-07 28.2 0.7 0.022 13.6 0.1 2.2 1 1 1 2 2 2 2 AFG1-like ATPase AAA_14 PF13173.6 ETZ06718.1 - 7.6e-06 26.0 0.1 2.6e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 ETZ06718.1 - 1.4e-05 25.2 2.4 0.00014 21.8 0.4 3.1 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 ETZ06718.1 - 6.5e-05 23.2 1.0 0.79 10.0 0.0 3.5 3 1 1 4 4 4 2 AAA domain NACHT PF05729.12 ETZ06718.1 - 0.00011 22.2 0.0 0.0033 17.3 0.0 2.5 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 ETZ06718.1 - 0.0002 21.7 0.1 0.0017 18.7 0.1 2.5 2 1 0 2 2 1 1 RNA helicase AAA_5 PF07728.14 ETZ06718.1 - 0.0013 18.8 0.0 0.0025 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ETZ06718.1 - 0.0036 17.7 1.4 0.046 14.1 0.0 2.9 3 1 1 4 4 4 1 AAA ATPase domain AAA_19 PF13245.6 ETZ06718.1 - 0.017 15.5 0.1 0.87 9.9 0.0 3.1 2 2 1 3 3 3 0 AAA domain TsaE PF02367.17 ETZ06718.1 - 0.024 14.7 0.0 0.059 13.4 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AFP_2 PF18815.1 ETZ06718.1 - 0.055 13.7 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 Bacterial antifreeze protein repeat AAA_25 PF13481.6 ETZ06718.1 - 0.063 12.8 0.0 0.78 9.3 0.0 2.0 1 1 1 2 2 2 0 AAA domain PyocinActivator PF11112.8 ETZ06718.1 - 0.069 13.3 0.3 0.54 10.4 0.1 2.4 2 0 0 2 2 2 0 Pyocin activator protein PrtN PhoH PF02562.16 ETZ06718.1 - 0.081 12.4 0.0 0.28 10.6 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Eaf7 PF07904.13 ETZ06718.1 - 0.09 13.2 2.3 2 8.9 0.0 2.9 3 0 0 3 3 3 0 Chromatin modification-related protein EAF7 AAA_7 PF12775.7 ETZ06718.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region CBM-like PF14683.6 ETZ06718.1 - 0.14 12.1 0.0 0.27 11.1 0.0 1.7 1 1 0 1 1 1 0 Polysaccharide lyase family 4, domain III RuvB_N PF05496.12 ETZ06718.1 - 0.15 11.8 0.1 1 9.1 0.1 2.2 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DNA_pol3_beta PF00712.19 ETZ06719.1 - 8.9e-25 87.2 0.1 7.5e-17 61.6 0.0 3.2 3 1 0 3 3 3 2 DNA polymerase III beta subunit, N-terminal domain DNA_pol3_beta_2 PF02767.16 ETZ06719.1 - 3.4e-19 69.2 0.1 7.5e-18 64.8 0.0 2.6 3 0 0 3 3 3 1 DNA polymerase III beta subunit, central domain DNA_pol3_beta_3 PF02768.15 ETZ06719.1 - 6.2e-17 61.5 0.0 1.8e-16 60.1 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase III beta subunit, C-terminal domain Peptidase_M20 PF01546.28 ETZ06720.1 - 3.9e-36 124.7 0.0 4.7e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ETZ06720.1 - 6.5e-11 42.1 0.0 1.4e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain tRNA-synt_2c PF01411.19 ETZ06721.1 - 5.8e-190 632.5 0.0 7.5e-190 632.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 ETZ06721.1 - 3.4e-19 68.7 2.2 9.7e-19 67.2 1.8 2.1 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF2325 PF10087.9 ETZ06722.1 - 0.13 12.4 1.7 0.69 10.1 0.1 2.9 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2325) DUF2198 PF09964.9 ETZ06724.1 - 0.22 11.6 4.6 0.88 9.7 3.4 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) SPOUT_MTase PF02590.17 ETZ06725.1 - 4.8e-27 94.8 0.0 2.7e-26 92.4 0.0 1.8 1 1 0 1 1 1 1 Predicted SPOUT methyltransferase Lon_C PF05362.13 ETZ06726.1 - 2.5e-73 246.0 0.0 4.7e-73 245.1 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 ETZ06726.1 - 7.2e-22 78.2 0.0 2.2e-21 76.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 ETZ06726.1 - 3.3e-16 59.8 1.3 3.3e-16 59.8 1.3 1.8 2 0 0 2 2 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA_5 PF07728.14 ETZ06726.1 - 2.9e-09 37.0 0.0 2.7e-08 33.9 0.0 2.7 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 ETZ06726.1 - 8.6e-09 35.7 0.1 5.7e-08 33.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 ETZ06726.1 - 2.9e-06 27.1 0.0 9.5e-05 22.2 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ETZ06726.1 - 0.0001 22.8 0.1 0.001 19.5 0.1 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_PrkA PF08298.11 ETZ06726.1 - 0.00013 21.0 0.2 0.00034 19.6 0.0 1.7 2 0 0 2 2 2 1 PrkA AAA domain ChlI PF13541.6 ETZ06726.1 - 0.00018 21.4 0.0 0.00036 20.4 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_18 PF13238.6 ETZ06726.1 - 0.00086 19.9 1.1 0.0042 17.6 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ETZ06726.1 - 0.0015 18.8 2.7 0.0074 16.6 0.0 3.2 3 1 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 ETZ06726.1 - 0.003 17.9 0.0 0.078 13.4 0.0 3.3 3 0 0 3 3 3 1 RNA helicase IstB_IS21 PF01695.17 ETZ06726.1 - 0.0034 17.2 0.1 0.0099 15.6 0.0 1.8 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 ETZ06726.1 - 0.0057 16.5 0.0 0.04 13.8 0.0 2.4 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 ETZ06726.1 - 0.011 15.5 0.0 0.042 13.6 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.6 ETZ06726.1 - 0.014 15.1 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ETZ06726.1 - 0.019 15.1 0.0 0.053 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 ETZ06726.1 - 0.021 14.8 0.3 0.12 12.3 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 ETZ06726.1 - 0.027 14.2 0.0 0.084 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ETZ06726.1 - 0.045 13.7 0.3 1.4 8.9 0.0 3.1 3 0 0 3 3 3 0 NACHT domain Parvo_NS1 PF01057.17 ETZ06726.1 - 0.055 12.6 0.0 0.12 11.4 0.0 1.6 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RsgA_GTPase PF03193.16 ETZ06726.1 - 0.077 12.9 0.1 0.28 11.1 0.0 1.9 2 0 0 2 2 1 0 RsgA GTPase AAA_17 PF13207.6 ETZ06726.1 - 0.079 13.4 5.2 0.1 13.0 0.1 3.2 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 ETZ06726.1 - 0.09 13.3 0.0 0.09 13.3 0.0 2.6 2 1 0 2 2 2 0 ABC transporter Torsin PF06309.11 ETZ06726.1 - 0.11 12.6 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 Torsin ATP-synt_ab PF00006.25 ETZ06726.1 - 0.2 11.2 0.0 0.57 9.8 0.0 1.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SKI PF01202.22 ETZ06726.1 - 0.32 11.1 0.0 0.32 11.1 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase AAA_11 PF13086.6 ETZ06726.1 - 2.8 7.7 0.0 2.8 7.7 0.0 2.4 1 1 1 2 2 2 0 AAA domain PG_isomerase_N PF18353.1 ETZ06727.1 - 0.049 14.0 0.9 0.15 12.5 0.0 2.3 3 0 0 3 3 3 0 Phosphoglucose isomerase N-terminal domain Protoglobin PF11563.8 ETZ06728.1 - 0.09 12.7 0.3 0.2 11.5 0.1 1.7 2 0 0 2 2 2 0 Protoglobin Utp12 PF04003.12 ETZ06728.1 - 0.1 12.9 0.0 0.34 11.2 0.0 1.8 2 0 0 2 2 2 0 Dip2/Utp12 Family DUF2380 PF09533.10 ETZ06729.1 - 0.0048 16.5 0.2 0.0086 15.7 0.2 1.4 1 0 0 1 1 1 1 Predicted lipoprotein of unknown function (DUF2380) PG_isomerase_N PF18353.1 ETZ06729.1 - 0.024 15.0 0.8 0.073 13.5 0.0 2.2 3 0 0 3 3 3 0 Phosphoglucose isomerase N-terminal domain Thioredoxin PF00085.20 ETZ06730.1 - 8.8e-19 67.4 0.0 9.8e-19 67.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 ETZ06730.1 - 6.3e-07 29.6 0.1 3.6e-05 24.0 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 ETZ06730.1 - 6.4e-07 29.8 0.0 1.4e-06 28.8 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 ETZ06730.1 - 1e-05 25.1 0.0 1.2e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 ETZ06730.1 - 0.00016 21.6 0.0 0.00018 21.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family TraF PF13728.6 ETZ06730.1 - 0.00069 19.5 0.0 0.00071 19.5 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Redoxin PF08534.10 ETZ06730.1 - 0.0017 18.1 0.0 0.002 17.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.6 ETZ06730.1 - 0.0046 16.7 0.1 0.0052 16.6 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin DUF953 PF06110.11 ETZ06730.1 - 0.01 15.5 0.3 0.037 13.6 0.3 1.7 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_3 PF13192.6 ETZ06730.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin domain Thioredoxin_7 PF13899.6 ETZ06730.1 - 0.02 15.0 0.2 0.03 14.5 0.2 1.5 1 1 0 1 1 1 0 Thioredoxin-like KaiB PF07689.12 ETZ06730.1 - 0.023 14.4 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 KaiB domain DUF836 PF05768.14 ETZ06730.1 - 0.027 14.9 0.0 0.036 14.5 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Cu-oxidase_4 PF02578.15 ETZ06731.1 - 1.1e-38 133.2 0.0 1.3e-38 132.9 0.0 1.0 1 0 0 1 1 1 1 Multi-copper polyphenol oxidoreductase laccase DALR_1 PF05746.15 ETZ06732.1 - 5.7e-22 78.1 0.0 1.1e-21 77.2 0.0 1.5 1 0 0 1 1 1 1 DALR anticodon binding domain tRNA-synt_1d PF00750.19 ETZ06732.1 - 1.6e-16 60.2 0.3 2.4e-12 46.5 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (R) tRNA-synt_1e PF01406.19 ETZ06732.1 - 2.5e-12 46.8 0.1 5.5e-07 29.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Arg_tRNA_synt_N PF03485.16 ETZ06732.1 - 1.2e-11 45.0 0.0 2.9e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1g PF09334.11 ETZ06732.1 - 2e-07 30.1 1.0 0.0019 17.0 0.1 3.2 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1f PF01921.18 ETZ06732.1 - 2.2e-06 26.9 0.0 1.1e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (K) tRNA-synt_1 PF00133.22 ETZ06732.1 - 0.00035 19.0 0.0 0.046 12.0 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) HTH_Tnp_4 PF13613.6 ETZ06733.1 - 3.2e-11 42.8 0.0 3.6e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease APG5 PF04106.12 ETZ06735.1 - 0.06 12.9 0.1 0.06 12.9 0.1 1.0 1 0 0 1 1 1 0 Autophagy protein Apg5 DDE_Tnp_1_assoc PF13808.6 ETZ06736.1 - 4.7e-23 81.0 0.0 1.3e-22 79.7 0.0 1.8 2 0 0 2 2 2 1 DDE_Tnp_1-associated DDE_Tnp_1 PF01609.21 ETZ06736.1 - 7.2e-13 48.7 0.3 1.1e-12 48.0 0.3 1.2 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_4 PF13701.6 ETZ06736.1 - 0.031 12.6 0.0 0.47 8.7 0.0 2.0 2 0 0 2 2 2 0 Transposase DDE domain group 1 NAD_kinase PF01513.21 ETZ06738.1 - 0.012 14.8 0.0 0.12 11.6 0.0 2.0 2 1 0 2 2 2 0 ATP-NAD kinase UDPG_MGDP_dh_N PF03721.14 ETZ06739.1 - 1e-33 116.5 0.0 1.6e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 ETZ06739.1 - 2.5e-22 78.9 0.1 5.2e-22 77.9 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 ETZ06739.1 - 5.8e-17 62.0 0.0 1.4e-16 60.8 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.15 ETZ06739.1 - 0.00085 19.5 0.0 0.0032 17.6 0.0 2.0 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Methyltransf_32 PF13679.6 ETZ06739.1 - 0.13 12.3 0.0 0.39 10.7 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Epimerase PF01370.21 ETZ06740.1 - 7e-44 150.1 0.0 8.5e-44 149.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ETZ06740.1 - 5e-40 137.9 0.0 5.9e-40 137.7 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ETZ06740.1 - 1.6e-10 40.4 0.0 2.3e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ETZ06740.1 - 1.1e-09 37.8 0.0 1.4e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 ETZ06740.1 - 1e-08 34.7 0.0 8.1e-08 31.7 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 ETZ06740.1 - 1.9e-07 30.5 0.0 7.5e-07 28.6 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 ETZ06740.1 - 6.5e-06 26.2 0.0 1.6e-05 24.9 0.0 1.7 2 1 0 2 2 2 1 KR domain adh_short PF00106.25 ETZ06740.1 - 0.03 13.8 0.0 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase SecG PF03840.14 ETZ06741.1 - 7.3e-11 42.0 5.2 1e-10 41.5 5.2 1.2 1 0 0 1 1 1 1 Preprotein translocase SecG subunit EIID-AGA PF03613.14 ETZ06741.1 - 0.0068 15.6 1.0 0.0068 15.6 1.0 1.0 1 0 0 1 1 1 1 PTS system mannose/fructose/sorbose family IID component SHR3_chaperone PF08229.11 ETZ06741.1 - 0.13 11.2 0.5 0.24 10.3 0.5 1.4 1 0 0 1 1 1 0 ER membrane protein SH3 DUF5533 PF17685.1 ETZ06741.1 - 2 8.8 5.7 14 6.0 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5533) SecE PF00584.20 ETZ06742.1 - 5.5e-12 45.4 6.2 6.7e-12 45.2 6.2 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex NusG PF02357.19 ETZ06743.1 - 7.6e-17 61.6 0.0 1.1e-16 61.1 0.0 1.2 1 0 0 1 1 1 1 Transcription termination factor nusG LAS2 PF15792.5 ETZ06743.1 - 0.13 12.8 0.0 0.3 11.6 0.0 1.6 1 0 0 1 1 1 0 Lung adenoma susceptibility protein 2 Ribosomal_L11_N PF03946.14 ETZ06744.1 - 6.6e-27 93.1 0.3 1.1e-26 92.5 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 ETZ06744.1 - 8.6e-18 64.6 0.2 1.7e-17 63.7 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Wzt_C PF14524.6 ETZ06744.1 - 0.13 12.3 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Wzt C-terminal domain Ribosomal_L1 PF00687.21 ETZ06745.1 - 4.6e-42 144.1 0.0 5.6e-42 143.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Phenol_hyd_sub PF06099.11 ETZ06745.1 - 0.03 14.3 0.2 0.088 12.8 0.0 1.8 2 0 0 2 2 2 0 Phenol hydroxylase subunit Ribosomal_L10 PF00466.20 ETZ06746.1 - 9e-15 54.6 0.1 1.2e-14 54.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_L12 PF00542.19 ETZ06747.1 - 9.9e-21 73.9 4.9 1.8e-20 73.0 4.9 1.4 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 ETZ06747.1 - 2.3e-16 59.2 0.7 2.3e-16 59.2 0.7 2.2 2 1 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain RNA_pol_Rpb2_6 PF00562.28 ETZ06749.1 - 1.4e-150 501.8 0.1 2.1e-149 497.9 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.16 ETZ06749.1 - 3.3e-28 97.6 0.1 9.2e-28 96.2 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_1 PF04563.15 ETZ06749.1 - 5.3e-25 88.1 0.0 2.2e-24 86.1 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 ETZ06749.1 - 2.2e-22 79.3 0.1 5.6e-22 78.0 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 ETZ06749.1 - 3.5e-21 75.7 0.1 1.7e-17 63.7 0.1 2.4 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_45 PF10385.9 ETZ06749.1 - 2.6e-16 59.6 0.9 1.1e-15 57.6 1.2 2.0 2 0 0 2 2 2 1 RNA polymerase beta subunit external 1 domain RNA_pol_Rpb1_1 PF04997.12 ETZ06750.1 - 8.1e-84 281.6 0.0 1.3e-83 280.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 ETZ06750.1 - 8.3e-62 209.0 0.0 1.4e-61 208.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 ETZ06750.1 - 2.2e-38 132.1 0.0 3.1e-27 95.8 0.0 2.5 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 ETZ06750.1 - 1.9e-21 76.6 0.0 4.2e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 ETZ06750.1 - 5.7e-12 45.5 0.1 1.6e-11 44.1 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Biotin_lipoyl_2 PF13533.6 ETZ06750.1 - 3.2e-07 30.1 0.1 0.21 11.4 0.1 3.7 3 0 0 3 3 3 2 Biotin-lipoyl like Apocytochr_F_C PF01333.19 ETZ06750.1 - 0.0092 16.0 0.0 2.3 8.3 0.0 2.7 2 0 0 2 2 2 1 Apocytochrome F, C-terminal YqfD PF06898.11 ETZ06750.1 - 0.17 10.7 0.5 1.5 7.6 0.0 2.4 3 0 0 3 3 3 0 Putative stage IV sporulation protein YqfD PGM_PMM_I PF02878.16 ETZ06751.1 - 2.6e-28 98.4 0.0 4.3e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 ETZ06751.1 - 2.3e-17 63.2 0.0 4.2e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 ETZ06751.1 - 1.7e-11 44.6 0.0 3.4e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 ETZ06751.1 - 8.3e-05 22.7 0.0 0.0002 21.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain ACPS PF01648.20 ETZ06752.1 - 5.2e-22 78.1 0.0 6e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Secretin PF00263.21 ETZ06753.1 - 1.3e-21 77.0 2.4 3.2e-21 75.7 2.1 1.7 2 0 0 2 2 2 1 Bacterial type II and III secretion system protein TPR_19 PF14559.6 ETZ06753.1 - 1.1e-08 35.4 3.7 0.0035 17.8 0.1 3.4 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 ETZ06753.1 - 2e-07 30.6 6.0 0.0017 18.3 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 ETZ06753.1 - 5.8e-07 29.6 0.0 0.028 14.6 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ETZ06753.1 - 0.00033 20.7 1.3 4.9 7.3 0.1 3.7 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 ETZ06753.1 - 0.0042 16.8 8.3 6.3 6.6 0.2 4.6 3 1 1 4 4 4 2 TPR repeat ANAPC3 PF12895.7 ETZ06753.1 - 0.0084 16.3 3.0 0.033 14.4 3.0 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 ETZ06753.1 - 0.0097 16.7 0.9 42 5.3 0.1 4.0 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 ETZ06753.1 - 0.014 15.2 6.4 0.63 10.0 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_18 PF13512.6 ETZ06753.1 - 0.029 14.5 0.3 0.058 13.5 0.3 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat YfiO PF13525.6 ETZ06753.1 - 0.045 13.5 1.8 0.081 12.6 1.8 1.4 1 0 0 1 1 1 0 Outer membrane lipoprotein TPR_17 PF13431.6 ETZ06753.1 - 0.11 12.9 8.3 30 5.3 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat N6-adenineMlase PF10237.9 ETZ06753.1 - 0.16 11.8 0.8 0.27 11.1 0.1 1.7 2 0 0 2 2 2 0 Probable N6-adenine methyltransferase TPR_16 PF13432.6 ETZ06753.1 - 0.28 11.9 0.2 0.28 11.9 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 ETZ06753.1 - 1 9.7 10.5 1.6 9.1 0.3 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Secretin PF00263.21 ETZ06754.1 - 7.7e-27 94.0 0.5 1.4e-26 93.1 0.5 1.4 1 0 0 1 1 1 1 Bacterial type II and III secretion system protein TPR_19 PF14559.6 ETZ06754.1 - 7.2e-08 32.8 10.5 0.0012 19.3 0.3 3.9 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 ETZ06754.1 - 2.9e-06 27.8 4.0 0.00019 22.0 0.2 3.5 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 ETZ06754.1 - 3.9e-06 26.6 11.8 0.032 14.3 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 ETZ06754.1 - 0.00048 19.8 7.1 0.25 11.1 0.4 4.0 4 0 0 4 4 4 2 TPR repeat TPR_14 PF13428.6 ETZ06754.1 - 0.0017 19.0 4.8 0.47 11.4 0.2 4.3 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 ETZ06754.1 - 0.02 15.2 3.4 0.18 12.3 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 ETZ06754.1 - 0.043 14.0 0.2 5.2 7.3 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ETZ06754.1 - 0.14 12.4 2.4 0.28 11.4 1.4 1.9 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 ETZ06754.1 - 0.17 12.0 3.4 0.31 11.1 0.1 2.8 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.6 ETZ06754.1 - 0.59 10.5 6.5 2.2 8.7 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 ETZ06754.1 - 0.78 10.1 8.3 0.25 11.6 2.5 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat Response_reg PF00072.24 ETZ06755.1 - 7.1e-19 68.0 0.0 1.3e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 ETZ06755.1 - 2.4e-18 66.7 0.0 5.2e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ETZ06755.1 - 1.5e-08 34.6 0.0 3.1e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 ETZ06755.1 - 0.036 14.0 0.0 0.12 12.2 0.0 2.0 1 0 0 1 1 1 0 GHKL domain HPTransfase PF10090.9 ETZ06755.1 - 0.043 13.6 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphotransferase C-terminal domain GTP1_OBG PF01018.22 ETZ06756.1 - 1.8e-48 164.0 6.9 2.5e-48 163.6 6.9 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 ETZ06756.1 - 2.3e-29 101.8 0.0 3.6e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ETZ06756.1 - 5.7e-16 58.4 0.0 8.8e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 ETZ06756.1 - 3.1e-06 27.3 0.0 0.038 14.1 0.0 2.5 1 1 1 2 2 2 2 Dynamin family cobW PF02492.19 ETZ06756.1 - 0.00021 20.9 0.2 0.12 11.9 0.0 2.2 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 ETZ06756.1 - 0.00029 20.4 1.0 0.6 9.6 0.4 2.6 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 ETZ06756.1 - 0.00088 19.3 0.1 0.0015 18.5 0.1 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Gtr1_RagA PF04670.12 ETZ06756.1 - 0.0022 17.4 0.1 0.0042 16.5 0.1 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MeaB PF03308.16 ETZ06756.1 - 0.0043 16.1 0.1 0.18 10.8 0.0 2.4 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 ETZ06756.1 - 0.0083 16.6 0.4 0.025 15.1 0.4 2.0 1 1 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 ETZ06756.1 - 0.011 15.7 8.4 0.52 10.2 0.2 3.4 3 1 1 4 4 3 0 RsgA GTPase Arf PF00025.21 ETZ06756.1 - 0.03 13.8 1.9 0.16 11.4 1.9 1.9 1 1 0 1 1 1 0 ADP-ribosylation factor family AAA_18 PF13238.6 ETZ06756.1 - 0.038 14.5 0.1 0.2 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain Casc1_N PF15927.5 ETZ06756.1 - 0.088 12.5 0.1 0.1 12.2 0.1 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus ATP_bind_1 PF03029.17 ETZ06756.1 - 0.09 12.5 0.1 14 5.3 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DASH_Dad3 PF08656.10 ETZ06756.1 - 0.1 12.7 0.3 0.21 11.7 0.3 1.5 1 0 0 1 1 1 0 DASH complex subunit Dad3 Ploopntkinase3 PF18751.1 ETZ06756.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Rotamase PF00639.21 ETZ06759.1 - 3.2e-06 28.0 0.0 8.1e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 ETZ06759.1 - 0.00055 20.5 0.0 0.0013 19.2 0.0 1.6 1 0 0 1 1 1 1 PPIC-type PPIASE domain Spore_III_AB PF09548.10 ETZ06759.1 - 0.016 15.3 1.2 0.12 12.4 0.1 2.5 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) AsnA PF03590.15 ETZ06759.1 - 0.062 13.0 0.6 2.8 7.6 0.1 2.2 2 0 0 2 2 2 0 Aspartate-ammonia ligase Ribosomal_TL5_C PF14693.6 ETZ06760.1 - 5.1e-23 81.3 1.8 7.7e-23 80.7 1.8 1.3 1 0 0 1 1 1 1 Ribosomal protein TL5, C-terminal domain Ribosomal_L25p PF01386.19 ETZ06760.1 - 4.9e-15 55.8 0.0 1.2e-14 54.6 0.0 1.6 2 0 0 2 2 2 1 Ribosomal L25p family Pept_tRNA_hydro PF01195.19 ETZ06761.1 - 1.1e-44 152.4 0.0 1.3e-44 152.2 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase RHSP PF07999.11 ETZ06762.1 - 0.02 13.7 0.6 0.029 13.2 0.6 1.3 1 0 0 1 1 1 0 Retrotransposon hot spot protein Phage_integrase PF00589.22 ETZ06762.1 - 0.068 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Phage integrase family PDDEXK_1 PF12705.7 ETZ06763.1 - 2.1e-14 54.0 0.0 3.5e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Glyco_hydro_7 PF00840.20 ETZ06763.1 - 0.05 12.3 0.3 0.079 11.7 0.3 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 7 IalB PF06776.12 ETZ06763.1 - 0.14 12.2 0.1 14 5.7 0.0 3.0 3 0 0 3 3 3 0 Invasion associated locus B (IalB) protein OmpH PF03938.14 ETZ06764.1 - 0.013 15.8 20.1 0.013 15.8 20.1 10.4 4 1 8 12 12 12 0 Outer membrane protein (OmpH-like) dUTPase PF00692.19 ETZ06765.1 - 5.3e-28 97.3 0.0 6.6e-28 97.0 0.0 1.0 1 0 0 1 1 1 1 dUTPase ATP_bind_3 PF01171.20 ETZ06766.1 - 4.4e-37 127.6 0.0 7.1e-37 126.9 0.0 1.3 1 0 0 1 1 1 1 PP-loop family Glu-tRNAGln PF02686.15 ETZ06767.1 - 3.7e-11 43.1 0.0 6.2e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit DUF3276 PF11680.8 ETZ06767.1 - 0.077 13.1 0.0 0.077 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3276) Amidase PF01425.21 ETZ06768.1 - 1e-141 473.0 0.0 1.2e-141 472.8 0.0 1.0 1 0 0 1 1 1 1 Amidase Ribosomal_S6 PF01250.17 ETZ06770.1 - 2.2e-19 69.5 0.0 3.1e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 Ribosomal_S18 PF01084.20 ETZ06771.1 - 6.2e-10 39.2 2.8 0.00044 20.4 0.1 2.5 1 1 1 2 2 2 2 Ribosomal protein S18 AGOG PF09171.10 ETZ06771.1 - 0.02 14.2 1.0 0.02 14.2 1.0 1.1 1 0 0 1 1 1 0 N-glycosylase/DNA lyase Ribosomal_L9_C PF03948.14 ETZ06773.1 - 4.1e-17 62.4 0.3 7e-17 61.7 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L9, C-terminal domain Ribosomal_L9_N PF01281.19 ETZ06773.1 - 1.2e-13 50.3 0.0 2.2e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain BRO1 PF03097.18 ETZ06773.1 - 0.0011 17.9 0.1 0.0013 17.6 0.1 1.0 1 0 0 1 1 1 1 BRO1-like domain EamA PF00892.20 ETZ06774.1 - 3.2e-12 46.8 37.1 3.2e-06 27.3 15.0 2.8 2 2 0 2 2 2 2 EamA-like transporter family DUF3265 PF11665.8 ETZ06774.1 - 0.42 10.9 4.1 0.46 10.8 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3265) DUF5368 PF17336.2 ETZ06774.1 - 0.6 10.3 9.6 4.7 7.4 0.2 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5368) Peptidase_M48 PF01435.18 ETZ06775.1 - 2.8e-21 76.2 0.2 4e-21 75.7 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M48 TPR_2 PF07719.17 ETZ06775.1 - 3.8e-07 29.7 6.0 0.012 15.6 0.0 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 ETZ06775.1 - 1.5e-05 24.6 3.6 0.019 14.7 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 ETZ06775.1 - 0.00017 22.1 1.3 0.63 11.0 0.0 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 ETZ06775.1 - 0.00033 21.2 0.3 1.1 10.0 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 ETZ06775.1 - 0.00035 21.0 0.8 0.018 15.5 0.1 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 ETZ06775.1 - 0.0032 17.6 3.5 0.96 9.8 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 ETZ06775.1 - 0.014 14.8 0.3 1.6 8.0 0.1 2.3 2 0 0 2 2 2 0 MalT-like TPR region ANAPC3 PF12895.7 ETZ06775.1 - 0.015 15.5 0.2 0.25 11.6 0.3 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 ETZ06775.1 - 0.018 14.8 0.0 4.1 7.2 0.0 3.1 3 0 0 3 3 3 0 TPR repeat TPR_15 PF13429.6 ETZ06775.1 - 0.028 13.6 0.7 0.095 11.9 0.2 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF2201_N PF13203.6 ETZ06775.1 - 0.064 12.9 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain TrkA_N PF02254.18 ETZ06776.1 - 1e-19 70.9 0.0 9.9e-12 45.1 0.2 2.6 2 0 0 2 2 2 2 TrkA-N domain TrkA_C PF02080.21 ETZ06776.1 - 4.4e-10 39.2 0.4 1e-06 28.5 0.0 3.2 4 0 0 4 4 4 2 TrkA-C domain Bac_DNA_binding PF00216.21 ETZ06777.1 - 1e-15 57.7 3.6 1.1e-15 57.5 3.6 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein LpxB PF02684.15 ETZ06778.1 - 1.6e-79 267.5 0.0 1.9e-79 267.2 0.0 1.0 1 0 0 1 1 1 1 Lipid-A-disaccharide synthetase PCIF1_WW PF12237.8 ETZ06778.1 - 0.068 12.8 0.0 0.26 10.9 0.0 1.9 2 0 0 2 2 2 0 Phosphorylated CTD interacting factor 1 WW domain PNTB_4TM PF12769.7 ETZ06779.1 - 2.1e-16 60.2 4.7 2.1e-16 60.2 4.7 1.7 2 0 0 2 2 2 1 4TM region of pyridine nucleotide transhydrogenase, mitoch Leader_Erm PF08253.11 ETZ06779.1 - 0.25 11.7 2.6 1.8 9.0 2.6 2.5 1 1 0 1 1 1 0 Erm Leader peptide AlaDh_PNT_C PF01262.21 ETZ06780.1 - 2.9e-49 167.3 0.0 3.8e-49 166.9 0.0 1.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 ETZ06780.1 - 7e-15 55.5 0.0 1.3e-14 54.7 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain 2-Hacid_dh_C PF02826.19 ETZ06780.1 - 0.0069 15.8 0.0 0.23 10.8 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 ETZ06780.1 - 0.13 11.5 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Aminotran_4 PF01063.19 ETZ06781.1 - 2.4e-45 155.1 0.0 2.8e-45 154.9 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV SNARE_assoc PF09335.11 ETZ06782.1 - 7.3e-11 42.6 8.3 7.3e-11 42.6 8.3 2.6 1 1 1 2 2 2 1 SNARE associated Golgi protein DUF373 PF04123.13 ETZ06782.1 - 0.37 10.2 7.9 0.52 9.7 7.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF373) MurB_C PF02873.16 ETZ06783.1 - 5.8e-21 74.8 0.0 1.1e-20 73.9 0.0 1.5 1 0 0 1 1 1 1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain FAD_binding_4 PF01565.23 ETZ06783.1 - 9.7e-18 64.2 0.0 3.2e-17 62.6 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Mur_ligase_C PF02875.21 ETZ06784.1 - 3.9e-22 78.3 0.0 8e-21 74.1 0.0 2.8 3 0 0 3 3 3 1 Mur ligase family, glutamate ligase domain Mur_ligase_M PF08245.12 ETZ06784.1 - 2e-21 76.9 0.4 3.7e-21 76.0 0.1 1.6 2 0 0 2 2 2 1 Mur ligase middle domain Mur_ligase PF01225.25 ETZ06784.1 - 1.1e-18 67.3 0.1 2.8e-18 66.0 0.1 1.7 1 0 0 1 1 1 1 Mur ligase family, catalytic domain BRCT PF00533.26 ETZ06784.1 - 0.003 17.9 0.1 0.0077 16.6 0.1 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF1256 PF06866.11 ETZ06784.1 - 0.043 13.2 0.0 0.41 10.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1256) DUF3134 PF11332.8 ETZ06784.1 - 0.1 13.0 0.1 0.4 11.0 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3134) Glyco_tran_28_C PF04101.16 ETZ06785.1 - 8.4e-17 61.6 0.0 9.2e-17 61.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_28 PF03033.20 ETZ06786.1 - 7.6e-16 58.4 0.0 1.2e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain SIS PF01380.22 ETZ06787.1 - 2.3e-44 150.4 0.2 4.4e-22 78.3 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 ETZ06787.1 - 1e-22 80.8 0.0 6.4e-22 78.2 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 ETZ06787.1 - 1.7e-17 63.5 0.0 8.5e-17 61.2 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.6 ETZ06787.1 - 0.033 13.1 0.0 0.055 12.4 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferases class-II SIS_2 PF13580.6 ETZ06787.1 - 0.073 13.1 0.0 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 SIS domain HhH-GPD PF00730.25 ETZ06788.1 - 1.6e-16 60.7 0.0 4.1e-16 59.4 0.0 1.6 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 ETZ06788.1 - 4.3e-16 58.9 0.1 8.2e-16 58.0 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain HHH PF00633.23 ETZ06788.1 - 0.00018 21.2 0.0 0.00035 20.3 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 ETZ06788.1 - 0.00026 21.2 6.0 0.00046 20.4 6.0 1.4 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III PDDEXK_1 PF12705.7 ETZ06788.1 - 0.099 12.5 0.1 5.2 6.9 0.0 2.2 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily Terminase_6 PF03237.15 ETZ06789.1 - 1e-19 71.1 0.0 3.2e-19 69.4 0.0 1.8 2 0 0 2 2 2 1 Terminase-like family Terminase_6C PF17289.2 ETZ06789.1 - 8.6e-07 29.2 0.0 2e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 Terminase RNaseH-like domain LptD PF04453.14 ETZ06790.1 - 8.7e-32 110.8 2.3 1.7e-31 109.8 2.3 1.5 1 0 0 1 1 1 1 LPS transport system D Pneumo_M2 PF07380.11 ETZ06790.1 - 1.4 9.3 3.5 0.4 11.0 0.1 1.9 2 0 0 2 2 2 0 Pneumovirus M2 protein UbiA PF01040.18 ETZ06792.1 - 6.9e-27 94.3 18.7 1e-26 93.8 18.7 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family Lysis_col PF02402.16 ETZ06793.1 - 0.011 15.4 0.5 0.011 15.4 0.5 1.7 2 0 0 2 2 2 0 Lysis protein Antimicrobial21 PF14861.6 ETZ06793.1 - 0.034 13.9 0.6 0.061 13.0 0.6 1.5 1 1 0 1 1 1 0 Plant antimicrobial peptide SpoU_methylase PF00588.19 ETZ06794.1 - 2.1e-25 89.6 0.0 5.6e-25 88.2 0.0 1.7 2 0 0 2 2 2 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 ETZ06794.1 - 0.00014 22.1 1.1 0.0036 17.5 0.2 3.0 2 1 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding RNase_H PF00075.24 ETZ06795.1 - 5.3e-38 130.4 0.1 9.8e-38 129.5 0.1 1.5 1 0 0 1 1 1 1 RNase H SH3_4 PF06347.13 ETZ06795.1 - 1.1e-20 73.1 5.6 4.9e-11 42.3 1.7 2.4 2 0 0 2 2 2 2 Bacterial SH3 domain SH3_3 PF08239.11 ETZ06795.1 - 0.00011 22.4 9.0 0.028 14.7 1.2 3.0 3 0 0 3 3 3 2 Bacterial SH3 domain RVT_3 PF13456.6 ETZ06795.1 - 0.012 15.4 0.0 0.036 13.9 0.0 1.9 1 1 0 1 1 1 0 Reverse transcriptase-like SH3_16 PF18348.1 ETZ06795.1 - 0.023 14.5 2.3 0.032 14.0 0.4 2.3 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain DUF4033 PF13225.6 ETZ06795.1 - 0.063 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4033) SH3_9 PF14604.6 ETZ06795.1 - 1.7 8.6 6.1 27 4.7 0.2 3.4 3 0 0 3 3 3 0 Variant SH3 domain Toprim_4 PF13662.6 ETZ06796.1 - 1.4e-17 63.9 0.0 2.5e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Toprim domain RecR PF02132.15 ETZ06796.1 - 4.1e-09 35.8 0.3 7e-09 35.1 0.3 1.3 1 0 0 1 1 1 1 RecR protein Toprim PF01751.22 ETZ06796.1 - 0.023 14.9 0.0 0.03 14.5 0.0 1.4 1 1 0 1 1 1 0 Toprim domain YbaB_DNA_bd PF02575.16 ETZ06797.1 - 3.3e-22 78.5 0.9 3.9e-22 78.3 0.9 1.0 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family Antimicrobial18 PF08130.11 ETZ06797.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Type A lantibiotic family ABC_tran PF00005.27 ETZ06798.1 - 2.6e-21 76.6 0.0 6.9e-21 75.2 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ETZ06798.1 - 6.9e-06 26.1 1.1 0.0002 21.3 0.1 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ETZ06798.1 - 0.00033 20.3 1.1 0.00067 19.4 1.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 ETZ06798.1 - 0.00071 20.1 2.4 0.00079 20.0 2.4 1.5 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 ETZ06798.1 - 0.0065 15.9 3.7 0.075 12.5 0.8 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 ETZ06798.1 - 0.013 15.8 1.4 0.34 11.2 1.4 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 ETZ06798.1 - 0.015 15.1 1.2 0.015 15.1 1.2 2.1 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 ETZ06798.1 - 0.028 14.3 0.3 0.068 13.1 0.1 1.7 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 ETZ06798.1 - 0.029 14.7 0.1 0.058 13.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 ETZ06798.1 - 0.042 13.2 0.2 0.074 12.4 0.2 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_ATPase PF09818.9 ETZ06798.1 - 0.058 12.2 0.5 0.086 11.6 0.5 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_16 PF13191.6 ETZ06798.1 - 0.064 13.6 0.1 0.15 12.5 0.1 1.6 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 ETZ06798.1 - 0.064 13.2 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 ETZ06798.1 - 0.076 13.2 0.1 0.17 12.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 ETZ06798.1 - 0.088 12.9 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase IIGP PF05049.13 ETZ06798.1 - 0.11 11.5 0.7 1.2 8.1 0.3 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_30 PF13604.6 ETZ06798.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ETZ06798.1 - 0.22 11.2 0.1 0.47 10.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain Ribosomal_L31 PF01197.18 ETZ06799.1 - 1.6e-19 69.9 0.1 1.9e-19 69.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L31 tRNA-synt_1b PF00579.25 ETZ06800.1 - 1.6e-68 231.2 0.0 2.1e-68 230.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 ETZ06800.1 - 0.0004 20.0 0.0 0.00092 18.9 0.0 1.6 1 0 0 1 1 1 1 S4 domain DUF4167 PF13763.6 ETZ06801.1 - 4e-21 74.9 1.2 4.1e-21 74.9 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4167) Desmo_N PF06771.11 ETZ06803.1 - 0.068 13.5 2.2 11 6.5 0.1 2.8 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus ANAPC2 PF08672.11 ETZ06803.1 - 0.4 11.2 5.5 11 6.7 0.0 3.8 5 0 0 5 5 5 0 Anaphase promoting complex (APC) subunit 2 Zip PF02535.22 ETZ06803.1 - 0.78 8.9 3.8 0.92 8.7 3.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 ETZ06803.1 - 8.1 5.1 15.5 0.18 10.6 8.9 1.6 2 0 0 2 2 2 0 Presenilin DUF948 PF06103.11 ETZ06803.1 - 8.2 6.8 11.2 9 6.6 0.8 3.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DDE_Tnp_4 PF13359.6 ETZ06804.1 - 6.4e-08 32.4 0.1 7.3e-08 32.2 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 ETZ06804.1 - 0.00038 20.2 0.1 0.00046 19.9 0.1 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 ETZ06804.1 - 0.011 16.1 0.1 0.012 15.9 0.1 1.1 1 0 0 1 1 1 0 Transposase DDE domain UPF0054 PF02130.17 ETZ06805.1 - 3.3e-24 85.1 0.0 4.1e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 CorC_HlyC PF03471.17 ETZ06806.1 - 9e-15 54.5 0.0 1.7e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Transporter associated domain CBS PF00571.28 ETZ06806.1 - 1.9e-10 41.0 0.0 6e-06 26.6 0.0 2.5 2 0 0 2 2 2 2 CBS domain TspO_MBR PF03073.15 ETZ06806.1 - 0.023 14.7 0.0 0.034 14.2 0.0 1.2 1 0 0 1 1 1 0 TspO/MBR family HTH_Tnp_IS630 PF01710.16 ETZ06807.1 - 1.5e-09 37.9 0.4 2e-09 37.5 0.4 1.3 1 1 0 1 1 1 1 Transposase HTH_23 PF13384.6 ETZ06807.1 - 1.1e-05 25.1 0.0 1.6e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 ETZ06807.1 - 3.4e-05 23.9 0.1 4.7e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 ETZ06807.1 - 0.0034 17.4 0.0 0.0043 17.0 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix PAX PF00292.18 ETZ06807.1 - 0.048 13.6 0.1 0.048 13.6 0.1 1.1 1 0 0 1 1 1 0 'Paired box' domain HTH_psq PF05225.16 ETZ06807.1 - 0.055 13.2 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_3 PF01381.22 ETZ06807.1 - 0.058 13.5 0.0 0.089 12.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix HTH_Tnp_ISL3 PF13542.6 ETZ06807.1 - 0.083 12.3 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DUF4806 PF16064.5 ETZ06807.1 - 0.14 12.4 0.9 0.18 12.1 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4806) DDE_3 PF13358.6 ETZ06808.1 - 2.8e-11 43.4 0.0 3.1e-11 43.2 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Pyr_redox_2 PF07992.14 ETZ06809.1 - 6.8e-24 84.6 0.0 8.6e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETZ06809.1 - 3.4e-22 79.1 0.0 1.2e-20 74.0 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETZ06809.1 - 2.4e-07 29.8 0.2 0.007 15.1 0.2 3.3 2 1 1 3 3 3 2 HI0933-like protein Pyr_redox PF00070.27 ETZ06809.1 - 4.9e-07 30.2 0.4 1.6e-05 25.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ETZ06809.1 - 0.0001 20.9 0.1 0.0018 16.8 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ETZ06809.1 - 0.00054 20.1 0.1 0.0017 18.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 ETZ06809.1 - 0.00061 19.0 0.1 0.0017 17.6 0.0 1.7 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 ETZ06809.1 - 0.004 16.6 0.0 0.014 14.8 0.0 1.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 ETZ06809.1 - 0.016 15.6 0.3 0.072 13.5 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding Thi4 PF01946.17 ETZ06809.1 - 0.022 14.0 0.2 0.3 10.3 0.2 2.1 2 0 0 2 2 2 0 Thi4 family DAO PF01266.24 ETZ06809.1 - 0.045 13.3 1.0 3.1 7.3 0.0 2.4 1 1 0 2 2 2 0 FAD dependent oxidoreductase Oxidored_nitro PF00148.19 ETZ06809.1 - 0.063 12.0 0.0 0.097 11.4 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Transpeptidase PF00905.22 ETZ06810.1 - 2.4e-38 132.1 0.0 3.1e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain PBP_dimer PF03717.15 ETZ06810.1 - 2.6e-09 37.7 0.0 6.8e-09 36.3 0.0 1.6 1 1 0 1 1 1 1 Penicillin-binding Protein dimerisation domain DUF4185 PF13810.6 ETZ06812.1 - 0.037 13.3 0.0 0.068 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4185) Prenyltransf PF01255.19 ETZ06813.1 - 2.5e-72 243.0 0.0 2.8e-72 242.9 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Cas_APE2256 PF09651.10 ETZ06813.1 - 0.08 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) DNA_pol3_delta2 PF13177.6 ETZ06814.1 - 2.4e-33 115.2 0.0 4.3e-33 114.4 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DNA_pol3_gamma3 PF12169.8 ETZ06814.1 - 1e-20 74.1 0.0 2e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III subunits gamma and tau domain III AAA PF00004.29 ETZ06814.1 - 8.2e-11 42.5 0.0 2e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ETZ06814.1 - 1e-07 32.3 0.3 4.9e-07 30.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ETZ06814.1 - 2.2e-06 27.7 0.3 0.099 12.6 0.0 2.7 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) DUF3646 PF12362.8 ETZ06814.1 - 6.2e-06 26.5 0.1 1.8e-05 25.1 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase III gamma and tau subunits C terminal RuvB_N PF05496.12 ETZ06814.1 - 6.4e-06 26.0 0.0 0.00063 19.5 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ETZ06814.1 - 1.8e-05 25.2 0.1 5.5e-05 23.6 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 ETZ06814.1 - 0.00031 20.8 0.3 0.0049 16.9 0.3 2.6 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 ETZ06814.1 - 0.00079 19.3 0.1 0.0023 17.7 0.1 1.7 1 0 0 1 1 1 1 DNA polymerase III, delta subunit TIP49 PF06068.13 ETZ06814.1 - 0.0011 18.3 0.1 0.94 8.6 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_24 PF13479.6 ETZ06814.1 - 0.0031 17.3 0.0 0.0069 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ETZ06814.1 - 0.0032 18.0 0.3 0.013 16.0 0.1 2.2 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.6 ETZ06814.1 - 0.0037 17.6 0.0 0.0077 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 ETZ06814.1 - 0.0059 16.5 0.2 0.015 15.2 0.2 1.9 1 1 0 1 1 1 1 NACHT domain TsaE PF02367.17 ETZ06814.1 - 0.011 15.7 0.1 0.025 14.6 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 ETZ06814.1 - 0.014 15.1 0.0 0.058 13.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 ETZ06814.1 - 0.021 14.7 0.4 0.094 12.6 0.4 2.0 2 0 0 2 2 2 0 NTPase ResIII PF04851.15 ETZ06814.1 - 0.036 14.1 0.8 0.78 9.7 0.0 2.7 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit Sigma54_activat PF00158.26 ETZ06814.1 - 0.036 13.8 0.1 0.16 11.7 0.1 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.6 ETZ06814.1 - 0.042 14.0 0.1 0.41 10.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 ETZ06814.1 - 0.062 13.4 0.1 2.4 8.3 0.0 2.7 2 1 0 2 2 1 0 Sigma-54 interaction domain T2SSE PF00437.20 ETZ06814.1 - 0.09 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.6 ETZ06814.1 - 0.14 12.4 1.8 0.23 11.7 0.4 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ETZ06814.1 - 0.15 12.5 0.0 0.45 10.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase CENP-X PF09415.10 ETZ06816.1 - 0.084 13.2 3.1 0.13 12.6 1.3 2.3 1 1 0 1 1 1 0 CENP-S associating Centromere protein X TPX2_importin PF12214.8 ETZ06816.1 - 0.087 13.0 5.4 0.12 12.6 5.4 1.2 1 0 0 1 1 1 0 Cell cycle regulated microtubule associated protein DUF4795 PF16043.5 ETZ06816.1 - 2.9 7.4 11.7 11 5.6 11.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) KH_5 PF13184.6 ETZ06817.1 - 1.4e-22 79.5 0.8 1.3e-20 73.3 0.1 2.8 2 1 0 2 2 2 1 NusA-like KH domain NusA_N PF08529.11 ETZ06817.1 - 3.8e-14 53.1 0.1 1.2e-13 51.5 0.1 1.9 1 0 0 1 1 1 1 NusA N-terminal domain KH_2 PF07650.17 ETZ06817.1 - 1.6e-06 27.8 4.4 3.6e-06 26.7 0.1 3.1 3 0 0 3 3 3 1 KH domain S1 PF00575.23 ETZ06817.1 - 8.4e-06 26.0 0.1 2.8e-05 24.4 0.1 2.0 1 0 0 1 1 1 1 S1 RNA binding domain KH_1 PF00013.29 ETZ06817.1 - 2.5e-05 24.0 0.2 0.0061 16.4 0.1 2.6 2 0 0 2 2 2 1 KH domain HHH_5 PF14520.6 ETZ06817.1 - 0.0011 19.5 0.0 0.056 14.1 0.0 2.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_2 PF12826.7 ETZ06817.1 - 0.041 14.0 0.1 0.11 12.6 0.1 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF3945 PF13101.6 ETZ06817.1 - 0.1 12.3 0.0 0.3 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3945) DUF150 PF02576.17 ETZ06818.1 - 2e-10 40.9 0.2 3.6e-10 40.1 0.2 1.4 1 0 0 1 1 1 1 RimP N-terminal domain DUF150_C PF17384.2 ETZ06818.1 - 0.00074 19.6 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 RimP C-terminal SH3 domain LSM14 PF12701.7 ETZ06818.1 - 0.12 12.5 0.1 0.2 11.8 0.1 1.4 1 0 0 1 1 1 0 Scd6-like Sm domain HlyD_D23 PF16576.5 ETZ06819.1 - 8.2e-14 51.3 0.0 1.1e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 ETZ06819.1 - 2.4e-09 36.8 0.3 1.8e-07 30.8 0.5 2.5 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 ETZ06819.1 - 0.003 18.2 0.0 0.32 11.7 0.0 2.6 2 1 0 2 2 2 1 HlyD family secretion protein Biotin_lipoyl PF00364.22 ETZ06819.1 - 0.0099 15.7 0.0 0.057 13.3 0.0 2.2 3 0 0 3 3 3 1 Biotin-requiring enzyme BPD_transp_1 PF00528.22 ETZ06820.1 - 1.7e-32 112.7 13.6 1.7e-32 112.7 13.6 2.0 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 ETZ06821.1 - 4.7e-22 78.6 9.8 7.5e-22 78.0 9.8 1.3 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 ETZ06821.1 - 0.28 11.2 0.1 0.28 11.2 0.1 3.6 3 1 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C ABC_tran PF00005.27 ETZ06822.1 - 9.2e-64 214.1 0.0 1.8e-34 119.2 0.0 2.2 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ETZ06822.1 - 1e-15 57.8 2.6 3.5e-08 33.2 0.4 2.6 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ETZ06822.1 - 2.8e-11 43.8 15.4 6.8e-06 26.1 0.7 4.0 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system oligo_HPY PF08352.12 ETZ06822.1 - 5.8e-10 39.6 0.0 4.1e-05 24.0 0.0 2.4 2 0 0 2 2 2 2 Oligopeptide/dipeptide transporter, C-terminal region AAA_29 PF13555.6 ETZ06822.1 - 1.2e-08 34.5 0.6 0.00039 20.1 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 ETZ06822.1 - 1.1e-07 32.2 8.3 0.023 15.0 0.3 4.1 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ETZ06822.1 - 1.5e-07 32.0 0.3 0.0024 18.3 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 ETZ06822.1 - 1e-05 25.5 1.5 0.017 15.1 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_5 PF07728.14 ETZ06822.1 - 2.2e-05 24.5 0.6 0.13 12.3 0.0 2.8 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 ETZ06822.1 - 2.4e-05 24.1 1.6 0.057 13.1 0.0 3.7 4 0 0 4 4 4 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 ETZ06822.1 - 2.7e-05 23.6 0.5 0.26 10.6 0.1 2.8 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 ETZ06822.1 - 4.1e-05 22.9 0.0 0.013 14.7 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain NACHT PF05729.12 ETZ06822.1 - 5e-05 23.3 2.0 0.058 13.3 0.2 2.7 2 1 0 2 2 2 2 NACHT domain ATPase PF06745.13 ETZ06822.1 - 5.2e-05 22.7 0.1 0.15 11.4 0.0 2.3 2 0 0 2 2 2 2 KaiC AAA PF00004.29 ETZ06822.1 - 0.00026 21.4 0.0 0.13 12.7 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 ETZ06822.1 - 0.00031 20.2 4.1 4.8 6.5 0.1 4.3 4 0 0 4 4 4 0 Bacterial TniB protein AAA_25 PF13481.6 ETZ06822.1 - 0.00036 20.2 0.1 0.71 9.4 0.1 2.5 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 ETZ06822.1 - 0.0012 18.6 4.5 0.099 12.3 0.0 3.1 4 0 0 4 4 3 1 Sigma-54 interaction domain AAA_7 PF12775.7 ETZ06822.1 - 0.0012 18.4 0.3 1.1 8.8 0.1 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_23 PF13476.6 ETZ06822.1 - 0.0017 18.9 1.2 0.071 13.6 0.1 2.5 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 ETZ06822.1 - 0.0019 17.4 0.2 0.54 9.4 0.0 2.7 2 1 0 2 2 2 1 NB-ARC domain AAA_18 PF13238.6 ETZ06822.1 - 0.0024 18.4 0.0 0.095 13.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain PPV_E1_C PF00519.17 ETZ06822.1 - 0.0034 16.3 0.4 0.18 10.6 0.1 2.1 2 0 0 2 2 2 1 Papillomavirus helicase DUF2075 PF09848.9 ETZ06822.1 - 0.0035 16.6 0.0 2 7.6 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) SbcCD_C PF13558.6 ETZ06822.1 - 0.0037 17.5 0.1 4.7 7.5 0.0 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 ETZ06822.1 - 0.0043 16.8 2.3 1.1 8.9 0.0 2.7 3 0 0 3 3 2 1 AAA domain EspG PF06872.11 ETZ06822.1 - 0.0046 15.6 0.1 0.0084 14.7 0.1 1.5 1 0 0 1 1 1 1 EspG protein T2SSE PF00437.20 ETZ06822.1 - 0.0074 15.4 0.1 0.79 8.7 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_33 PF13671.6 ETZ06822.1 - 0.008 16.4 0.0 2.5 8.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 ETZ06822.1 - 0.0082 16.5 0.0 1.1 9.7 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_15 PF13175.6 ETZ06822.1 - 0.011 15.5 0.1 3.3 7.3 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain ABC_ATPase PF09818.9 ETZ06822.1 - 0.011 14.6 0.1 1.7 7.3 0.0 3.0 3 0 0 3 3 3 0 Predicted ATPase of the ABC class APS_kinase PF01583.20 ETZ06822.1 - 0.015 15.2 0.7 0.48 10.3 0.1 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase PRK PF00485.18 ETZ06822.1 - 0.018 14.8 0.0 0.2 11.4 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_30 PF13604.6 ETZ06822.1 - 0.018 14.8 0.0 0.92 9.2 0.0 2.7 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 ETZ06822.1 - 0.018 15.1 0.1 0.81 9.8 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.17 ETZ06822.1 - 0.021 14.9 1.5 2.1 8.4 0.1 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain ATP-synt_ab PF00006.25 ETZ06822.1 - 0.032 13.9 0.0 0.68 9.6 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PIF1 PF05970.14 ETZ06822.1 - 0.047 12.9 0.1 4.4 6.4 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase PhoH PF02562.16 ETZ06822.1 - 0.049 13.1 0.1 5.5 6.4 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein G-alpha PF00503.20 ETZ06822.1 - 0.16 11.1 0.7 1 8.4 0.2 2.0 2 0 0 2 2 2 0 G-protein alpha subunit Roc PF08477.13 ETZ06822.1 - 0.64 10.3 2.6 17 5.6 0.0 2.7 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase Peptidase_M23 PF01551.22 ETZ06822.1 - 0.89 9.8 4.3 18 5.6 0.0 3.7 4 1 0 4 4 3 0 Peptidase family M23 Pox_A32 PF04665.12 ETZ06822.1 - 1.7 8.0 7.6 1.5 8.2 0.1 3.3 3 1 0 4 4 3 0 Poxvirus A32 protein DUF4435 PF14491.6 ETZ06825.1 - 0.13 12.2 2.9 0.56 10.1 3.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4435) GAD-like PF08887.11 ETZ06825.1 - 0.15 11.8 0.1 0.26 11.1 0.1 1.3 1 0 0 1 1 1 0 GAD-like domain TrkH PF02386.16 ETZ06826.1 - 8.3e-13 47.6 7.8 8.3e-13 47.6 7.8 2.8 2 1 1 3 3 3 2 Cation transport protein PNTB PF02233.16 ETZ06827.1 - 4.2e-142 474.3 9.0 5.1e-142 474.0 9.0 1.0 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit TPP_enzyme_M PF00205.22 ETZ06827.1 - 0.025 14.3 0.1 0.12 12.1 0.1 2.1 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain DUF3501 PF12007.8 ETZ06828.1 - 2.7e-31 109.0 0.0 3.8e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3501) Response_reg PF00072.24 ETZ06829.1 - 3.3e-24 85.2 0.0 4.9e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 ETZ06829.1 - 9.8e-18 64.0 0.0 2.4e-17 62.8 0.0 1.7 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Glutaredoxin PF00462.24 ETZ06830.1 - 6.6e-15 55.1 0.0 1e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF2491 PF10679.9 ETZ06830.1 - 0.19 10.9 0.1 0.24 10.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) Phage_int_SAM_1 PF02899.17 ETZ06831.1 - 0.011 16.0 0.0 0.052 13.9 0.0 1.8 1 1 1 2 2 2 0 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 ETZ06831.1 - 0.14 12.7 0.0 0.15 12.6 0.0 1.2 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Phage_integrase PF00589.22 ETZ06832.1 - 7.9e-35 120.2 0.0 1.1e-34 119.7 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 ETZ06832.1 - 1.7e-05 25.0 0.4 0.0003 21.0 0.2 2.5 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_integr_3 PF16795.5 ETZ06832.1 - 0.0055 16.6 0.1 2 8.3 0.0 2.3 2 0 0 2 2 2 2 Archaeal phage integrase Acetyltransf_11 PF13720.6 ETZ06832.1 - 0.0062 17.0 0.3 0.099 13.1 0.0 2.3 1 1 1 2 2 2 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 FMN_red PF03358.15 ETZ06833.1 - 4e-13 49.4 0.0 4.5e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 ETZ06833.1 - 1.5e-10 41.1 0.0 2.1e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold IPPT PF01715.17 ETZ06834.1 - 1.2e-43 149.6 0.0 1.5e-43 149.3 0.0 1.0 1 0 0 1 1 1 1 IPP transferase AAA_33 PF13671.6 ETZ06834.1 - 0.00068 19.8 0.0 0.0038 17.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain IPT PF01745.16 ETZ06834.1 - 0.0027 17.1 0.0 0.0046 16.4 0.0 1.4 1 0 0 1 1 1 1 Isopentenyl transferase AAA_18 PF13238.6 ETZ06834.1 - 0.018 15.6 0.0 0.38 11.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 ETZ06834.1 - 0.022 14.5 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase Zeta_toxin PF06414.12 ETZ06834.1 - 0.098 11.9 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Hydin_ADK PF17213.3 ETZ06834.1 - 0.18 12.1 0.2 0.36 11.1 0.1 1.5 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA_16 PF13191.6 ETZ06834.1 - 0.2 12.1 0.0 0.36 11.2 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain DDE_Tnp_1_2 PF13586.6 ETZ06835.1 - 0.022 15.1 0.1 0.022 15.1 0.1 1.0 1 0 0 1 1 1 0 Transposase DDE domain DUF1699 PF08004.11 ETZ06838.1 - 0.05 13.3 0.1 0.057 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1699) DUF4096 PF13340.6 ETZ06840.1 - 9.9e-07 28.9 0.0 1.1e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) POTRA PF07244.15 ETZ06841.1 - 6.4e-40 135.6 9.1 3.4e-13 49.9 0.4 5.5 5 0 0 5 5 5 5 Surface antigen variable number repeat Bac_surface_Ag PF01103.23 ETZ06841.1 - 1.4e-34 120.1 12.5 2.2e-34 119.4 12.5 1.4 1 0 0 1 1 1 1 Surface antigen POTRA_2 PF08479.11 ETZ06841.1 - 3.6e-08 33.1 0.5 3.6e-05 23.5 0.1 4.1 5 0 0 5 5 5 1 POTRA domain, ShlB-type POTRA_1 PF08478.10 ETZ06841.1 - 0.016 15.5 1.0 5.6 7.3 0.0 3.6 3 0 0 3 3 3 0 POTRA domain, FtsQ-type DUF4794 PF16042.5 ETZ06841.1 - 0.28 12.2 0.3 0.54 11.3 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4794) TGT PF01702.18 ETZ06844.1 - 4.4e-99 332.0 0.0 5.4e-99 331.7 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Thioredoxin_4 PF13462.6 ETZ06844.1 - 0.054 13.6 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 Thioredoxin PseudoU_synth_2 PF00849.22 ETZ06845.1 - 5.7e-33 114.3 0.3 8e-33 113.8 0.3 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 ETZ06845.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 S4 domain FtsX PF02687.21 ETZ06846.1 - 4e-06 27.2 6.4 4e-06 27.2 6.4 3.2 2 1 0 3 3 3 1 FtsX-like permease family ABC_tran PF00005.27 ETZ06847.1 - 6.2e-31 107.7 0.0 9e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter Rad17 PF03215.15 ETZ06847.1 - 1.3e-06 28.4 0.2 6.6e-06 26.2 0.2 1.9 2 0 0 2 2 2 1 Rad17 P-loop domain SMC_N PF02463.19 ETZ06847.1 - 9e-06 25.3 0.0 1.6e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ETZ06847.1 - 0.00012 22.5 0.2 0.00017 22.0 0.2 1.5 1 1 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 ETZ06847.1 - 0.00013 21.1 0.2 0.00021 20.5 0.2 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_21 PF13304.6 ETZ06847.1 - 0.00018 21.4 0.7 0.0023 17.8 0.3 2.1 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 ETZ06847.1 - 0.00033 20.3 0.1 0.0005 19.7 0.1 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ETZ06847.1 - 0.00034 20.5 0.7 0.0007 19.5 0.7 1.6 1 1 0 1 1 1 1 RsgA GTPase Mg_chelatase PF01078.21 ETZ06847.1 - 0.0004 19.8 0.1 0.00072 19.0 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 ETZ06847.1 - 0.00068 19.3 0.8 0.0013 18.4 0.8 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 ETZ06847.1 - 0.00079 20.0 0.0 0.0055 17.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 ETZ06847.1 - 0.001 19.6 0.1 0.0013 19.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 ETZ06847.1 - 0.0012 18.8 0.0 0.0018 18.2 0.0 1.3 1 1 0 1 1 1 1 NACHT domain AAA PF00004.29 ETZ06847.1 - 0.0017 18.8 0.2 0.003 18.0 0.2 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ETZ06847.1 - 0.002 18.4 1.6 0.0061 16.8 1.6 2.0 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 ETZ06847.1 - 0.0021 18.1 0.0 0.0048 16.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 ETZ06847.1 - 0.0021 18.0 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_28 PF13521.6 ETZ06847.1 - 0.0049 17.1 0.0 0.0073 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 ETZ06847.1 - 0.012 15.6 0.0 0.031 14.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ETZ06847.1 - 0.013 15.1 0.4 0.12 11.9 0.2 2.1 1 1 1 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 ETZ06847.1 - 0.015 15.3 0.1 0.025 14.6 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 ETZ06847.1 - 0.02 14.6 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ETZ06847.1 - 0.026 13.8 0.0 0.054 12.8 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.15 ETZ06847.1 - 0.028 14.4 0.2 0.063 13.2 0.1 1.7 2 0 0 2 2 1 0 NTPase ATPase PF06745.13 ETZ06847.1 - 0.03 13.7 0.2 0.056 12.8 0.2 1.4 1 0 0 1 1 1 0 KaiC PduV-EutP PF10662.9 ETZ06847.1 - 0.034 13.9 0.2 0.062 13.0 0.2 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Adeno_IVa2 PF02456.15 ETZ06847.1 - 0.038 12.8 0.1 0.054 12.3 0.1 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein RNA_helicase PF00910.22 ETZ06847.1 - 0.041 14.3 0.0 0.097 13.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PRK PF00485.18 ETZ06847.1 - 0.049 13.4 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.22 ETZ06847.1 - 0.053 13.1 0.0 0.092 12.4 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain TIP49 PF06068.13 ETZ06847.1 - 0.053 12.7 0.1 0.1 11.8 0.0 1.5 2 0 0 2 2 2 0 TIP49 P-loop domain RuvB_N PF05496.12 ETZ06847.1 - 0.071 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain cobW PF02492.19 ETZ06847.1 - 0.076 12.6 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain PIF1 PF05970.14 ETZ06847.1 - 0.083 12.0 0.1 0.32 10.1 0.0 1.8 2 0 0 2 2 2 0 PIF1-like helicase DLIC PF05783.11 ETZ06847.1 - 0.095 11.5 0.1 0.14 11.0 0.1 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) APS_kinase PF01583.20 ETZ06847.1 - 0.15 12.0 0.2 0.33 10.8 0.1 1.6 2 0 0 2 2 1 0 Adenylylsulphate kinase AAA_24 PF13479.6 ETZ06847.1 - 0.22 11.2 1.4 0.3 10.8 0.7 1.6 2 0 0 2 2 1 0 AAA domain AAA_19 PF13245.6 ETZ06847.1 - 0.34 11.3 1.2 0.73 10.2 1.2 1.9 1 1 0 1 1 1 0 AAA domain Poxvirus_B22R_N PF13169.6 ETZ06848.1 - 0.042 14.3 1.1 0.042 14.3 1.1 4.5 4 1 1 5 5 5 0 Poxvirus B22R protein N-terminal Sda PF08970.10 ETZ06848.1 - 2.8 7.8 6.4 17 5.2 1.4 3.7 2 1 0 2 2 2 0 Sporulation inhibitor A TIM21 PF08294.11 ETZ06848.1 - 2.9 7.8 5.5 72 3.2 0.0 4.1 4 1 1 5 5 5 0 TIM21 Glycos_transf_4 PF00953.21 ETZ06849.1 - 4.1e-30 104.9 15.4 4.1e-30 104.9 15.4 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 4 MraY_sig1 PF10555.9 ETZ06849.1 - 7.6 6.3 11.7 0.2 11.3 4.9 2.0 2 0 0 2 2 2 0 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 Methyltransf_23 PF13489.6 ETZ06850.1 - 2.5e-16 59.9 0.0 3.5e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETZ06850.1 - 2.5e-11 44.0 0.0 5.3e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETZ06850.1 - 5.1e-10 39.9 0.0 9.2e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETZ06850.1 - 1.6e-09 37.7 0.0 2.3e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETZ06850.1 - 3.6e-08 34.0 0.0 7.9e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 ETZ06850.1 - 2.8e-05 23.7 0.0 3.5e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 ETZ06850.1 - 5e-05 23.0 0.0 7.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.11 ETZ06850.1 - 0.00045 19.2 0.0 0.00058 18.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 ETZ06850.1 - 0.0029 17.0 0.0 0.0037 16.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 ETZ06850.1 - 0.039 13.5 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.17 ETZ06850.1 - 0.05 12.8 0.0 3.1 6.9 0.0 2.2 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Peptidase_S9 PF00326.21 ETZ06850.1 - 0.092 12.2 0.0 0.17 11.3 0.0 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family Methyltransf_18 PF12847.7 ETZ06850.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 ETZ06850.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB ApoO PF09769.9 ETZ06851.1 - 0.11 12.4 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein O tRNA_m1G_MT PF01746.21 ETZ06853.1 - 1.9e-47 161.5 0.0 2.4e-47 161.2 0.0 1.0 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase EFP_N PF08207.12 ETZ06854.1 - 8.6e-19 67.3 0.2 2.7e-18 65.7 0.0 1.9 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain Elong-fact-P_C PF09285.11 ETZ06854.1 - 1.4e-18 66.3 0.0 3.4e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP PF01132.20 ETZ06854.1 - 1.2e-14 54.0 0.6 2.1e-14 53.3 0.6 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain Transket_pyr PF02779.24 ETZ06855.1 - 6.6e-46 156.2 0.0 1e-45 155.6 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ETZ06855.1 - 7.8e-37 125.9 0.0 3.1e-36 124.0 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 ETZ06855.1 - 0.0018 18.5 0.0 0.0035 17.6 0.0 1.5 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II 2-oxoacid_dh PF00198.23 ETZ06856.1 - 2.1e-74 249.9 0.5 2.9e-74 249.4 0.5 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 ETZ06856.1 - 8.2e-17 60.8 0.0 1.8e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 ETZ06856.1 - 3.1e-11 43.4 0.0 7.4e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain Ribosomal_S2 PF00318.20 ETZ06859.1 - 8e-83 276.9 0.0 1.1e-82 276.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S2 EF_TS PF00889.19 ETZ06860.1 - 5.3e-53 179.7 0.0 7.3e-53 179.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor TS GLYCAM-1 PF05242.11 ETZ06860.1 - 0.22 11.6 2.1 0.55 10.4 0.4 2.1 1 1 0 2 2 2 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) AA_kinase PF00696.28 ETZ06861.1 - 4.1e-19 69.1 0.0 5.5e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Amino acid kinase family MoCF_biosynth PF00994.24 ETZ06861.1 - 0.11 12.2 0.3 0.73 9.5 0.1 2.1 2 0 0 2 2 2 0 Probable molybdopterin binding domain Ribosomal_L28 PF00830.19 ETZ06862.1 - 2.6e-18 65.9 1.6 2.6e-18 65.9 1.6 1.6 2 0 0 2 2 2 1 Ribosomal L28 family FtsK_SpoIIIE PF01580.18 ETZ06863.1 - 4.7e-61 206.2 0.0 7.7e-61 205.5 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family FtsK_gamma PF09397.10 ETZ06863.1 - 1.3e-27 95.4 0.9 2.9e-27 94.2 0.9 1.7 1 0 0 1 1 1 1 Ftsk gamma domain FtsK_alpha PF17854.1 ETZ06863.1 - 2e-25 88.9 0.0 4e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 FtsK alpha domain FtsK_4TM PF13491.6 ETZ06863.1 - 2.4e-16 59.9 12.9 3.9e-16 59.2 12.9 1.4 1 0 0 1 1 1 1 4TM region of DNA translocase FtsK/SpoIIIE DUF87 PF01935.17 ETZ06863.1 - 8.9e-06 26.0 0.1 2.6e-05 24.5 0.1 1.7 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_10 PF12846.7 ETZ06863.1 - 2.7e-05 23.3 0.0 0.049 12.6 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain AAA_19 PF13245.6 ETZ06863.1 - 0.017 15.5 0.0 0.042 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 ETZ06863.1 - 0.064 13.3 0.0 0.16 12.0 0.0 1.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ETZ06863.1 - 0.066 13.5 0.6 0.32 11.3 0.6 2.1 1 1 0 1 1 1 0 AAA domain Phage_30_8 PF06019.11 ETZ06863.1 - 0.075 12.9 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Phage GP30.8 protein EAP30 PF04157.16 ETZ06863.1 - 0.16 11.3 0.1 0.33 10.2 0.1 1.6 1 1 0 1 1 1 0 EAP30/Vps36 family TniB PF05621.11 ETZ06863.1 - 0.19 11.1 4.2 26 4.1 0.0 3.9 4 0 0 4 4 4 0 Bacterial TniB protein POTRA_1 PF08478.10 ETZ06865.1 - 1.3e-12 47.8 0.6 2.5e-12 46.9 0.2 1.7 2 0 0 2 2 2 1 POTRA domain, FtsQ-type FtsQ PF03799.15 ETZ06865.1 - 2.8e-06 28.2 0.1 4.7e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 Cell division protein FtsQ DUF2818 PF10993.8 ETZ06865.1 - 0.37 11.4 2.5 0.48 11.0 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2818) FtsA PF14450.6 ETZ06866.1 - 1.2e-22 80.3 0.0 2.5e-17 63.2 0.0 2.1 2 0 0 2 2 2 2 Cell division protein FtsA SHS2_FTSA PF02491.20 ETZ06866.1 - 3.5e-11 43.3 0.0 7.8e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain inserted in FTSA MreB_Mbl PF06723.13 ETZ06866.1 - 5e-08 32.1 0.0 1.1e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.16 ETZ06866.1 - 6.7e-07 29.2 0.1 2.5e-06 27.3 0.1 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain PilM_2 PF11104.8 ETZ06866.1 - 8.8e-07 28.3 0.0 0.032 13.3 0.0 2.3 2 0 0 2 2 2 2 Type IV pilus assembly protein PilM; BcrAD_BadFG PF01869.20 ETZ06866.1 - 0.072 12.6 0.0 2.1 7.7 0.1 2.5 2 1 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Actin PF00022.19 ETZ06866.1 - 0.13 10.8 0.1 11 4.5 0.0 2.2 1 1 0 2 2 2 0 Actin Tubulin PF00091.25 ETZ06867.1 - 8.4e-39 133.8 0.0 1.6e-38 132.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 ETZ06867.1 - 4.1e-24 84.7 1.5 6e-24 84.2 0.4 1.9 2 0 0 2 2 2 1 FtsZ family, C-terminal domain Tubulin_2 PF13809.6 ETZ06867.1 - 0.0056 15.9 5.7 0.13 11.4 0.0 2.6 1 1 1 2 2 2 2 Tubulin like DUF2854 PF11016.8 ETZ06867.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) EamA PF00892.20 ETZ06868.1 - 6.2e-18 65.3 35.5 3.4e-09 37.0 15.5 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 ETZ06868.1 - 5.7e-06 25.9 18.0 2.9e-05 23.6 10.9 2.3 1 1 1 2 2 2 2 Triose-phosphate Transporter family Acyl_transf_1 PF00698.21 ETZ06870.1 - 9.5e-40 137.0 0.0 1.2e-39 136.8 0.0 1.0 1 0 0 1 1 1 1 Acyl transferase domain polyprenyl_synt PF00348.17 ETZ06871.1 - 5.2e-42 143.7 0.0 6.8e-42 143.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 ETZ06871.1 - 0.0012 18.5 0.0 0.0023 17.5 0.0 1.5 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 ALIX_LYPXL_bnd PF13949.6 ETZ06871.1 - 0.0089 15.4 0.4 0.018 14.4 0.3 1.5 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV DUF4291 PF14124.6 ETZ06874.1 - 0.074 12.9 0.2 0.094 12.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4291) Phage_capsid PF05065.13 ETZ06875.1 - 2.2e-36 125.6 0.0 2.7e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 Phage capsid family DUF16 PF01519.16 ETZ06875.1 - 0.093 13.2 0.5 0.19 12.2 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 Peptidase_S78 PF04586.17 ETZ06876.1 - 3.6e-23 82.5 0.0 4.7e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Caudovirus prohead serine protease Phage_portal PF04860.12 ETZ06877.1 - 4.9e-72 242.8 0.0 5.6e-72 242.6 0.0 1.0 1 0 0 1 1 1 1 Phage portal protein CodY PF06018.14 ETZ06877.1 - 0.14 11.6 0.0 0.46 10.0 0.0 1.8 2 1 0 2 2 2 0 CodY GAF-like domain 2OG-FeII_Oxy_5 PF13759.6 ETZ06878.1 - 0.14 12.6 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase UPF0102 PF02021.17 ETZ06879.1 - 1.3e-11 44.5 0.0 1.7e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0102 DUF4143 PF13635.6 ETZ06879.1 - 0.0097 16.1 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4143) NERD PF08378.11 ETZ06879.1 - 0.041 14.3 0.0 0.05 14.1 0.0 1.2 1 0 0 1 1 1 0 Nuclease-related domain NucS PF01939.16 ETZ06879.1 - 0.12 11.7 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Endonuclease NucS DUF3971 PF13116.6 ETZ06880.1 - 8.9e-14 51.7 0.5 2.3e-13 50.4 0.5 1.7 1 0 0 1 1 1 1 Protein of unknown function Cut8 PF08559.10 ETZ06880.1 - 0.098 12.3 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein AsmA_1 PF13109.6 ETZ06881.1 - 1.8e-06 27.6 0.2 1.2e-05 24.9 0.0 2.1 2 1 0 2 2 2 1 AsmA-like C-terminal region AsmA_2 PF13502.6 ETZ06881.1 - 0.0094 15.5 0.2 0.037 13.6 0.0 2.1 2 1 0 2 2 2 1 AsmA-like C-terminal region DUF4096 PF13340.6 ETZ06882.1 - 1.1e-11 44.8 0.3 1.3e-11 44.5 0.3 1.1 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) Peptidase_M1 PF01433.20 ETZ06884.1 - 0.013 15.0 0.6 0.024 14.2 0.6 1.5 1 0 0 1 1 1 0 Peptidase family M1 domain YMF19 PF02326.15 ETZ06885.1 - 0.03 15.1 1.1 0.03 15.1 1.1 1.7 1 1 1 2 2 2 0 Plant ATP synthase F0 DDE_Tnp_1_3 PF13612.6 ETZ06886.1 - 0.006 16.6 0.1 0.0071 16.4 0.1 1.1 1 0 0 1 1 1 1 Transposase DDE domain DUF3917 PF13055.6 ETZ06886.1 - 0.11 12.9 0.0 0.14 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3917) Fe-S_biosyn PF01521.20 ETZ06887.1 - 5.3e-15 55.6 0.1 6.3e-15 55.3 0.1 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis G3P_acyltransf PF02660.15 ETZ06888.1 - 4.2e-42 144.0 13.6 4.9e-42 143.8 13.6 1.0 1 0 0 1 1 1 1 Glycerol-3-phosphate acyltransferase DDE_Tnp_1 PF01609.21 ETZ06889.1 - 0.00085 19.0 0.2 0.005 16.5 0.1 1.8 1 1 1 2 2 2 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 ETZ06889.1 - 0.0046 17.3 0.1 0.0052 17.1 0.1 1.1 1 0 0 1 1 1 1 Transposase DDE domain DNA_pol3_delta2 PF13177.6 ETZ06890.1 - 4.8e-21 75.2 0.0 8.1e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_2 PF07724.14 ETZ06891.1 - 2e-47 161.5 0.1 2.9e-47 160.9 0.1 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) zf-C4_ClpX PF06689.13 ETZ06891.1 - 8.1e-20 70.4 4.4 2.2e-19 69.0 4.4 1.8 1 0 0 1 1 1 1 ClpX C4-type zinc finger AAA PF00004.29 ETZ06891.1 - 3.9e-17 62.9 0.0 1.2e-16 61.4 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 ETZ06891.1 - 1.4e-13 50.7 0.4 1.4e-13 50.7 0.4 2.0 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein MCM PF00493.23 ETZ06891.1 - 3.2e-06 26.4 0.1 5e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 MCM P-loop domain AAA_5 PF07728.14 ETZ06891.1 - 3.9e-06 26.9 0.0 6e-05 23.1 0.1 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 ETZ06891.1 - 5.7e-06 25.9 0.1 0.0011 18.4 0.1 3.0 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 ETZ06891.1 - 5.1e-05 23.0 0.1 0.00094 18.9 0.1 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.6 ETZ06891.1 - 0.00016 22.0 0.1 0.00069 19.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 ETZ06891.1 - 0.00021 21.0 0.3 0.0008 19.2 0.3 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 ETZ06891.1 - 0.0013 18.3 0.0 0.0028 17.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 ETZ06891.1 - 0.002 18.2 0.1 0.0096 16.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ETZ06891.1 - 0.0058 16.8 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 ETZ06891.1 - 0.0079 15.4 0.4 0.033 13.4 0.1 1.9 1 1 1 2 2 2 1 TIP49 P-loop domain Sigma54_activ_2 PF14532.6 ETZ06891.1 - 0.013 15.6 0.0 0.043 13.9 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 ETZ06891.1 - 0.018 14.8 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.6 ETZ06891.1 - 0.033 14.6 0.1 0.1 13.0 0.1 1.7 2 1 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 ETZ06891.1 - 0.034 14.7 0.0 0.077 13.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter ATPase PF06745.13 ETZ06891.1 - 0.052 12.9 1.8 1.2 8.5 0.1 2.3 1 1 1 2 2 2 0 KaiC Zeta_toxin PF06414.12 ETZ06891.1 - 0.052 12.8 0.1 0.13 11.5 0.1 1.6 1 1 0 1 1 1 0 Zeta toxin T2SSE PF00437.20 ETZ06891.1 - 0.08 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 ETZ06891.1 - 0.085 12.6 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_8 PF12780.7 ETZ06891.1 - 0.093 12.0 0.0 0.22 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 AAA_18 PF13238.6 ETZ06891.1 - 0.093 13.3 0.2 0.37 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ETZ06891.1 - 0.097 13.1 0.1 0.26 11.7 0.1 1.9 1 1 0 1 1 1 0 RNA helicase NACHT PF05729.12 ETZ06891.1 - 0.12 12.3 0.2 0.65 9.9 0.0 2.1 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 ETZ06891.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CLP_protease PF00574.23 ETZ06892.1 - 6.4e-80 267.3 0.0 7.5e-80 267.1 0.0 1.0 1 0 0 1 1 1 1 Clp protease NMO PF03060.15 ETZ06894.1 - 1.4e-46 159.5 0.0 2.2e-43 148.9 0.0 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 ETZ06894.1 - 8e-06 25.1 0.6 1.5e-05 24.2 0.6 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 ETZ06894.1 - 0.00024 20.4 0.1 0.00039 19.7 0.1 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase IMPDH PF00478.25 ETZ06894.1 - 0.0013 17.8 0.0 0.07 12.1 0.1 2.4 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 ETZ06894.1 - 0.0052 16.1 0.1 0.0079 15.5 0.1 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG ThiC_Rad_SAM PF01964.18 ETZ06894.1 - 0.02 13.7 0.0 2.4 6.8 0.0 2.1 2 0 0 2 2 2 0 Radical SAM ThiC family AA_kinase PF00696.28 ETZ06895.1 - 5e-44 150.7 0.1 6.7e-44 150.3 0.1 1.1 1 0 0 1 1 1 1 Amino acid kinase family MFS_1 PF07690.16 ETZ06896.1 - 6.8e-27 94.3 77.6 7.3e-20 71.2 45.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETZ06896.1 - 8e-24 84.3 37.3 2.9e-17 62.7 13.0 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter Peptidase_C26 PF07722.13 ETZ06897.1 - 3.8e-55 187.0 0.0 4.5e-55 186.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase C26 GATase PF00117.28 ETZ06897.1 - 6.5e-20 71.7 0.1 1.5e-19 70.5 0.1 1.6 1 1 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 ETZ06897.1 - 0.0032 17.1 0.5 0.0058 16.3 0.5 1.5 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain MlaC PF05494.12 ETZ06898.1 - 1.3e-14 54.3 0.0 3.3e-14 53.0 0.0 1.6 1 1 1 2 2 2 1 MlaC protein GxDLY PF14607.6 ETZ06898.1 - 0.032 14.0 0.0 0.068 13.0 0.0 1.5 1 0 0 1 1 1 0 N-terminus of Esterase_SGNH_hydro-type SAM_PNT PF02198.16 ETZ06898.1 - 0.11 12.5 0.1 0.32 11.0 0.0 1.7 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain T2SSE PF00437.20 ETZ06899.1 - 1.5e-65 221.0 0.0 2.6e-65 220.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein T2SSE_N PF05157.15 ETZ06899.1 - 1.6e-05 25.1 0.0 3.4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein E, N-terminal domain AAA_14 PF13173.6 ETZ06899.1 - 2.2e-05 24.5 0.1 7.1e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 ETZ06899.1 - 2.9e-05 24.5 0.1 6.4e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 ETZ06899.1 - 0.00058 19.8 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 ETZ06899.1 - 0.0022 18.3 0.0 0.0054 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 ETZ06899.1 - 0.0036 17.3 0.1 0.0071 16.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 ETZ06899.1 - 0.0039 17.7 0.1 0.0097 16.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ETZ06899.1 - 0.0085 15.9 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 ETZ06899.1 - 0.0087 16.6 0.0 0.022 15.3 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ATPase_2 PF01637.18 ETZ06899.1 - 0.023 14.6 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 ETZ06899.1 - 0.026 14.2 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 ETZ06899.1 - 0.028 14.8 0.1 0.14 12.5 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 ETZ06899.1 - 0.062 13.7 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 ETZ06899.1 - 0.069 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 ETZ06899.1 - 0.097 13.1 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 ETZ06899.1 - 0.12 12.2 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 ETZ06899.1 - 0.21 11.5 0.8 5.9 6.8 0.2 2.5 1 1 1 2 2 2 0 NTPase T2SSF PF00482.23 ETZ06900.1 - 2.6e-22 79.1 0.6 2.3e-14 53.4 0.0 2.7 3 0 0 3 3 3 2 Type II secretion system (T2SS), protein F ESSS PF10183.9 ETZ06900.1 - 0.44 10.8 1.5 5.3 7.3 0.1 2.4 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Acyl_transf_3 PF01757.22 ETZ06904.1 - 0.0011 18.1 48.2 0.13 11.3 39.4 3.1 1 1 1 2 2 2 2 Acyltransferase family LpxK PF02606.14 ETZ06905.1 - 2.9e-59 200.8 0.0 3.9e-59 200.4 0.0 1.1 1 0 0 1 1 1 1 Tetraacyldisaccharide-1-P 4'-kinase Glyco_transf_4 PF13439.6 ETZ06905.1 - 0.013 15.6 0.0 0.042 13.9 0.0 1.8 2 0 0 2 2 2 0 Glycosyltransferase Family 4 ArsA_ATPase PF02374.15 ETZ06905.1 - 0.05 12.8 0.1 0.072 12.3 0.1 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase DUF5615 PF18480.1 ETZ06905.1 - 0.11 12.2 0.0 5 7.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5615) PS_Dcarbxylase PF02666.15 ETZ06906.1 - 3.3e-25 88.8 0.0 2.1e-22 79.7 0.0 2.0 2 0 0 2 2 2 2 Phosphatidylserine decarboxylase Proteasome_A_N PF10584.9 ETZ06906.1 - 0.15 11.7 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature IF3_C PF00707.22 ETZ06907.1 - 0.027 14.5 0.0 0.033 14.2 0.0 1.1 1 0 0 1 1 1 0 Translation initiation factor IF-3, C-terminal domain Inositol_P PF00459.25 ETZ06908.1 - 8.6e-51 173.0 0.0 1.1e-50 172.7 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family NUDIX PF00293.28 ETZ06909.1 - 1.2e-20 73.9 0.0 1.5e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain RPAP2_Rtr1 PF04181.13 ETZ06909.1 - 0.073 13.4 0.0 0.17 12.2 0.0 1.7 2 0 0 2 2 2 0 Rtr1/RPAP2 family OmpA PF00691.20 ETZ06910.1 - 1.2e-14 54.4 0.0 4.3e-14 52.7 0.0 1.9 2 0 0 2 2 2 1 OmpA family HrpB7 PF09486.10 ETZ06910.1 - 0.012 16.1 3.5 0.019 15.4 3.5 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Exonuc_VII_L PF02601.15 ETZ06910.1 - 0.1 12.2 5.3 0.15 11.6 5.3 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF5070 PF16802.5 ETZ06910.1 - 0.4 10.7 4.5 1.1 9.2 0.4 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF5070) LapA_dom PF06305.11 ETZ06910.1 - 7.2 6.5 9.2 6.4 6.7 1.0 3.4 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain SMC_N PF02463.19 ETZ06911.1 - 5.5e-17 61.9 0.0 1.3e-15 57.5 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 ETZ06911.1 - 6.6e-11 42.5 0.1 3.1e-08 33.8 0.1 2.1 1 1 1 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 ETZ06911.1 - 1.6e-10 41.9 0.5 3.1e-10 40.9 0.5 1.7 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 ETZ06911.1 - 2.4e-08 34.2 0.0 3.8e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 ETZ06911.1 - 3.6e-05 23.9 0.0 6.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 ETZ06911.1 - 0.00015 22.3 1.0 0.03 14.8 0.1 2.3 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 ETZ06911.1 - 0.00046 19.9 0.1 0.0066 16.2 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 ETZ06911.1 - 0.00071 19.9 0.2 0.16 12.3 0.1 3.0 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 ETZ06911.1 - 0.0024 17.8 0.3 0.59 10.0 0.2 2.5 2 0 0 2 2 2 1 NACHT domain DUF2813 PF11398.8 ETZ06911.1 - 0.036 13.3 0.0 0.036 13.3 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) AAA_30 PF13604.6 ETZ06911.1 - 0.086 12.5 0.1 5.5 6.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 ETZ06911.1 - 0.086 13.1 0.3 0.88 9.8 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Terminase_3C PF17288.2 ETZ06911.1 - 0.18 12.2 0.2 0.44 10.9 0.2 1.6 2 0 0 2 2 2 0 Terminase RNAseH like domain N_methyl PF07963.12 ETZ06913.1 - 0.0066 16.0 0.2 0.01 15.3 0.2 1.3 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif PTN_MK_N PF05196.13 ETZ06913.1 - 0.092 13.0 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 PTN/MK heparin-binding protein family, N-terminal domain NMO PF03060.15 ETZ06914.1 - 6.3e-11 42.2 0.0 1.2e-10 41.3 0.0 1.4 1 1 0 1 1 1 1 Nitronate monooxygenase LptF_LptG PF03739.14 ETZ06915.1 - 2.2e-23 82.7 0.0 2.8e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG SprT-like PF10263.9 ETZ06915.1 - 0.24 11.3 0.7 0.71 9.8 0.1 1.9 1 1 0 2 2 2 0 SprT-like family LptF_LptG PF03739.14 ETZ06916.1 - 4e-08 32.5 23.6 1.7e-07 30.5 23.6 1.8 1 1 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG SSB PF00436.25 ETZ06919.1 - 2.5e-35 120.7 0.1 3.2e-35 120.3 0.1 1.2 1 0 0 1 1 1 1 Single-strand binding protein family DUF677 PF05055.12 ETZ06919.1 - 0.0069 15.3 0.3 0.0084 15.0 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF677) Cytotoxic PF09000.10 ETZ06919.1 - 0.11 12.8 1.4 13 6.2 0.1 2.2 2 0 0 2 2 2 0 Cytotoxic CCDC106 PF15794.5 ETZ06920.1 - 0.38 10.4 2.0 0.47 10.1 2.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DEAD PF00270.29 ETZ06921.1 - 2.6e-15 56.6 0.0 4.8e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ETZ06921.1 - 1.2e-12 48.2 0.0 4e-12 46.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETZ06921.1 - 4.5e-05 23.5 0.0 0.0001 22.3 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit RecG_wedge PF17191.4 ETZ06921.1 - 8e-05 22.3 0.0 0.33 10.6 0.1 2.4 2 0 0 2 2 2 2 RecG wedge domain SecA_DEAD PF07517.14 ETZ06921.1 - 0.041 13.2 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain AAA_29 PF13555.6 ETZ06921.1 - 0.18 11.6 0.0 0.42 10.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 ETZ06921.1 - 0.19 12.0 0.7 12 6.2 0.1 3.3 2 1 1 3 3 3 0 AAA domain Hexapep PF00132.24 ETZ06922.1 - 1.2e-17 62.8 2.6 0.00024 20.7 0.1 4.3 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 ETZ06922.1 - 7.3e-15 55.7 0.0 1.1e-14 55.1 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 ETZ06922.1 - 3.1e-06 26.8 6.5 1.6e-05 24.5 0.1 4.0 4 1 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.19 ETZ06922.1 - 0.0008 19.4 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase IspD PF01128.19 ETZ06922.1 - 0.0011 18.8 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase MbeD_MobD PF04899.12 ETZ06922.1 - 0.055 13.6 0.5 0.12 12.5 0.5 1.5 1 0 0 1 1 1 0 MbeD/MobD like rve PF00665.26 ETZ06924.1 - 7.2e-08 32.6 0.0 8e-08 32.5 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain Secretin PF00263.21 ETZ06925.1 - 2.2e-33 115.3 0.2 5.5e-33 114.0 0.2 1.7 1 0 0 1 1 1 1 Bacterial type II and III secretion system protein Secretin_N_2 PF07655.13 ETZ06925.1 - 2.1e-05 25.0 1.7 5.7e-05 23.6 1.7 1.7 1 0 0 1 1 1 1 Secretin N-terminal domain DUF4974 PF16344.5 ETZ06925.1 - 4.5e-05 23.4 0.0 0.00016 21.6 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4974) Ala_racemase_N PF01168.20 ETZ06925.1 - 0.0024 17.6 0.0 0.0048 16.6 0.0 1.5 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain TEX13 PF15186.6 ETZ06925.1 - 0.0027 17.4 0.1 0.0076 15.9 0.0 1.7 1 1 0 1 1 1 1 Testis-expressed sequence 13 protein family STN PF07660.14 ETZ06925.1 - 0.022 14.6 1.2 3.7 7.4 0.0 3.0 3 0 0 3 3 3 0 Secretin and TonB N terminus short domain HIGH_NTase1_ass PF16581.5 ETZ06926.1 - 0.34 10.9 6.4 0.069 13.1 2.7 1.8 2 0 0 2 2 2 0 Cytidyltransferase-related C-terminal region Trypan_PARP PF05887.11 ETZ06926.1 - 3.2 7.8 7.5 5 7.1 7.2 1.5 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Poxvirus_B22R_N PF13169.6 ETZ06927.1 - 0.03 14.8 6.6 0.071 13.6 0.2 3.4 3 0 0 3 3 3 0 Poxvirus B22R protein N-terminal GerD PF17898.1 ETZ06927.1 - 0.038 13.9 0.4 14 5.7 0.0 4.8 4 1 0 4 4 4 0 Spore germination GerD central core domain Erf4 PF10256.9 ETZ06927.1 - 0.3 11.2 9.1 1.7 8.8 0.0 5.0 4 2 1 5 5 5 0 Golgin subfamily A member 7/ERF4 family DDE_3 PF13358.6 ETZ06928.1 - 4.4e-05 23.3 0.0 4.6e-05 23.2 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease ATP-synt_ab PF00006.25 ETZ06931.1 - 4.9e-24 85.2 0.0 6.8e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Rho_RNA_bind PF07497.12 ETZ06931.1 - 3.3e-22 78.1 0.0 6.4e-22 77.2 0.0 1.5 1 0 0 1 1 1 1 Rho termination factor, RNA-binding domain AAA PF00004.29 ETZ06931.1 - 0.0045 17.4 0.1 0.01 16.3 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rho_N PF07498.12 ETZ06931.1 - 0.0047 16.8 0.0 0.013 15.4 0.0 1.9 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain NACHT PF05729.12 ETZ06931.1 - 0.0067 16.3 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_25 PF13481.6 ETZ06931.1 - 0.0098 15.5 0.1 0.057 13.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ETZ06931.1 - 0.011 16.1 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 ETZ06931.1 - 0.029 14.3 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 ETZ06931.1 - 0.035 14.5 0.0 0.22 11.9 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain DUF3754 PF12576.8 ETZ06931.1 - 0.094 12.7 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) AAA_14 PF13173.6 ETZ06931.1 - 0.11 12.5 0.1 1 9.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain Terminase_GpA PF05876.12 ETZ06931.1 - 0.13 10.8 0.0 2.2 6.7 0.0 2.0 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) AAA_19 PF13245.6 ETZ06931.1 - 0.18 12.2 0.1 0.86 9.9 0.0 1.9 1 1 1 2 2 2 0 AAA domain LGT PF01790.18 ETZ06932.1 - 8.5e-63 211.8 13.5 9.6e-63 211.6 13.5 1.0 1 0 0 1 1 1 1 Prolipoprotein diacylglyceryl transferase DDE_Tnp_IS1 PF03400.13 ETZ06934.1 - 0.0014 19.0 0.0 0.0015 18.9 0.0 1.1 1 0 0 1 1 1 1 IS1 transposase CPT PF07931.12 ETZ06935.1 - 1.7e-12 47.5 0.2 1.9e-12 47.4 0.2 1.0 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein NUDIX PF00293.28 ETZ06936.1 - 0.0004 20.4 0.0 0.0005 20.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain HTH_Tnp_IS630 PF01710.16 ETZ06940.1 - 1.8e-09 37.7 1.0 2e-09 37.5 1.0 1.0 1 0 0 1 1 1 1 Transposase PAX PF00292.18 ETZ06940.1 - 2e-05 24.5 0.0 2e-05 24.5 0.0 1.0 1 0 0 1 1 1 1 'Paired box' domain ECSIT_C PF14784.6 ETZ06940.1 - 0.024 15.0 0.1 0.026 14.9 0.1 1.2 1 0 0 1 1 1 0 C-terminal domain of the ECSIT protein DUF3510 PF12022.8 ETZ06941.1 - 0.0084 16.5 1.8 0.27 11.6 0.8 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3510) Spore_III_AE PF09546.10 ETZ06942.1 - 0.073 12.3 0.3 0.093 11.9 0.3 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AE (spore_III_AE) DUF4096 PF13340.6 ETZ06944.1 - 1.8e-17 63.3 1.5 2.3e-17 63.0 1.5 1.1 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1 PF01609.21 ETZ06946.1 - 1.1e-07 31.8 3.4 0.0029 17.3 0.0 2.0 1 1 1 2 2 2 2 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 ETZ06946.1 - 7.8e-05 23.0 0.1 0.0001 22.6 0.1 1.2 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 ETZ06946.1 - 0.044 13.4 0.3 0.14 11.8 0.2 1.7 1 1 1 2 2 2 0 DDE superfamily endonuclease DUF717 PF05338.12 ETZ06947.1 - 0.015 15.4 0.0 0.25 11.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF717) Ntox28 PF15605.6 ETZ06947.1 - 0.021 15.0 1.6 0.057 13.7 0.1 2.4 2 0 0 2 2 2 0 Bacterial toxin 28 FapA PF03961.13 ETZ06947.1 - 0.022 13.4 7.0 0.035 12.7 7.0 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF3959 PF13105.6 ETZ06947.1 - 0.2 11.2 0.1 0.2 11.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3959) STAT_alpha PF01017.20 ETZ06947.1 - 0.4 10.6 6.1 1.4 8.8 6.1 2.0 1 1 0 1 1 1 0 STAT protein, all-alpha domain Occludin_ELL PF07303.13 ETZ06947.1 - 0.91 10.3 8.0 0.73 10.6 1.7 3.1 3 2 1 4 4 4 0 Occludin homology domain SesA PF17107.5 ETZ06947.1 - 1.1 9.5 4.9 2.9 8.1 1.0 2.8 2 1 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF1788 PF08747.11 ETZ06947.1 - 2.9 7.9 9.0 1.1 9.3 3.0 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF1788) SurA_N_3 PF13624.6 ETZ06949.1 - 1.4e-17 63.9 0.1 3.8e-17 62.5 0.1 1.8 1 1 0 1 1 1 1 SurA N-terminal domain SurA_N_2 PF13623.6 ETZ06949.1 - 7.8e-12 45.3 0.0 1.9e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 SurA N-terminal domain Rotamase_2 PF13145.6 ETZ06949.1 - 8.2e-09 36.3 4.5 0.00048 21.0 1.0 2.8 2 1 0 2 2 2 2 PPIC-type PPIASE domain RBD PF02196.15 ETZ06949.1 - 0.074 13.1 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Raf-like Ras-binding domain GerE PF00196.19 ETZ06949.1 - 0.076 12.6 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family RsfS PF02410.15 ETZ06950.1 - 3.5e-23 81.9 0.2 4.4e-23 81.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation DUF3417 PF11897.8 ETZ06951.1 - 0.061 13.8 0.0 13 6.2 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3417) LON_substr_bdg PF02190.16 ETZ06951.1 - 0.27 11.1 6.1 22 4.8 0.2 4.3 4 2 0 4 4 4 0 ATP-dependent protease La (LON) substrate-binding domain tRNA-synt_1c PF00749.21 ETZ06954.1 - 6.9e-57 192.7 0.1 1.2e-56 191.9 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Bac_DnaA PF00308.18 ETZ06955.1 - 9.8e-06 25.6 0.0 0.018 14.9 0.0 2.1 2 0 0 2 2 2 2 Bacterial dnaA protein RuvB_N PF05496.12 ETZ06955.1 - 0.035 13.8 0.0 0.82 9.4 0.0 2.0 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain LolA PF03548.15 ETZ06956.1 - 9.5e-11 41.7 0.1 1.2e-10 41.4 0.1 1.1 1 0 0 1 1 1 1 Outer membrane lipoprotein carrier protein LolA Hexapep PF00132.24 ETZ06957.1 - 8.3e-10 38.0 10.0 4e-05 23.2 1.1 3.9 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 ETZ06957.1 - 4.5e-09 35.9 5.5 2.2e-06 27.3 0.5 3.0 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase THDPS_N_2 PF14805.6 ETZ06957.1 - 2e-05 24.7 0.0 3.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrodipicolinate N-succinyltransferase N-terminal DUF3697 PF12478.8 ETZ06957.1 - 0.068 13.3 0.1 0.66 10.1 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-associated protein 2 S1 PF00575.23 ETZ06958.1 - 3.6e-80 264.3 28.2 1.9e-19 69.8 0.4 6.2 6 0 0 6 6 6 6 S1 RNA binding domain S1_2 PF13509.6 ETZ06958.1 - 2e-06 27.8 4.2 3.6 7.7 0.0 6.1 6 2 0 6 6 6 3 S1 domain PCB_OB PF17092.5 ETZ06958.1 - 1e-05 26.2 4.0 1.7 9.4 0.0 4.9 3 2 2 5 5 5 3 Penicillin-binding protein OB-like domain TRAM PF01938.20 ETZ06958.1 - 0.016 15.2 7.9 1 9.4 0.1 5.7 5 1 0 5 5 5 0 TRAM domain PCRF PF03462.18 ETZ06959.1 - 6e-59 199.2 0.4 6e-59 199.2 0.4 1.9 2 1 0 2 2 2 1 PCRF domain RF-1 PF00472.20 ETZ06959.1 - 6.3e-41 139.0 2.4 6.3e-41 139.0 2.4 1.9 2 0 0 2 2 2 1 RF-1 domain FliT PF05400.13 ETZ06959.1 - 0.12 13.2 1.0 0.12 13.2 1.0 2.2 2 0 0 2 2 2 0 Flagellar protein FliT DUF3537 PF12056.8 ETZ06959.1 - 0.52 9.1 2.9 5.1 5.8 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3537) HAD_2 PF13419.6 ETZ06960.1 - 1.2e-13 51.6 0.0 2.3e-13 50.6 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ETZ06960.1 - 0.00056 20.3 0.0 0.00072 19.9 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ETZ06960.1 - 0.043 13.9 0.0 0.078 13.0 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like PurL_C PF16904.5 ETZ06960.1 - 0.097 13.0 0.1 0.18 12.1 0.1 1.4 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine synthase II C-terminus OGG_N PF07934.12 ETZ06960.1 - 0.1 12.7 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 8-oxoguanine DNA glycosylase, N-terminal domain Transketolase_N PF00456.21 ETZ06961.1 - 4e-116 387.6 0.0 5.7e-116 387.1 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 ETZ06961.1 - 8.5e-39 133.1 0.0 2e-38 131.8 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.6 ETZ06961.1 - 2.5e-06 26.9 0.0 0.0028 16.9 0.0 2.3 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 ETZ06961.1 - 1.4e-05 24.2 0.0 4.4e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 ETZ06961.1 - 0.0029 17.4 0.0 0.029 14.1 0.0 2.3 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_C PF02780.20 ETZ06961.1 - 0.052 13.4 0.0 0.42 10.5 0.0 2.3 3 0 0 3 3 3 0 Transketolase, C-terminal domain RRM_3 PF08777.11 ETZ06962.1 - 0.25 11.4 3.8 0.97 9.5 0.3 2.2 2 0 0 2 2 2 0 RNA binding motif DNA_pol_B_exo2 PF10108.9 ETZ06962.1 - 0.4 10.3 2.5 5.8 6.5 2.5 2.1 1 1 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB ANAPC5 PF12862.7 ETZ06963.1 - 0.084 13.0 1.4 0.094 12.8 0.2 1.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 GTP_EFTU PF00009.27 ETZ06964.1 - 5.4e-31 107.7 6.1 5.4e-31 107.7 6.1 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 ETZ06964.1 - 1.4e-27 95.9 0.7 1.4e-27 95.9 0.7 2.5 2 0 0 2 2 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 ETZ06964.1 - 1.1e-10 41.6 0.3 1.1e-10 41.6 0.3 2.6 3 0 0 3 3 3 1 50S ribosome-binding GTPase IF2_N PF04760.15 ETZ06964.1 - 5.7e-09 35.7 0.4 5.7e-09 35.7 0.4 2.7 3 0 0 3 3 2 1 Translation initiation factor IF-2, N-terminal region GTP_EFTU_D2 PF03144.25 ETZ06964.1 - 4.1e-07 30.3 0.5 0.0041 17.5 0.0 3.5 2 0 0 2 2 2 2 Elongation factor Tu domain 2 SRPRB PF09439.10 ETZ06964.1 - 8e-07 28.7 0.3 8e-07 28.7 0.3 2.4 2 1 0 2 2 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 ETZ06964.1 - 7.1e-06 25.8 0.3 1.8e-05 24.5 0.3 1.7 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Ras PF00071.22 ETZ06964.1 - 7.6e-05 22.4 0.2 7.6e-05 22.4 0.2 1.9 2 0 0 2 2 1 1 Ras family FeoB_N PF02421.18 ETZ06964.1 - 0.00022 20.8 2.4 0.0011 18.5 2.4 2.3 1 1 0 1 1 1 1 Ferrous iron transport protein B Roc PF08477.13 ETZ06964.1 - 0.00036 20.7 0.1 0.00096 19.4 0.1 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 ETZ06964.1 - 0.00098 19.1 6.1 0.041 13.8 0.7 2.8 1 1 1 2 2 2 2 RsgA GTPase IF2_assoc PF08364.11 ETZ06964.1 - 0.0025 18.1 3.9 0.0025 18.1 3.9 2.6 2 0 0 2 2 2 1 Bacterial translation initiation factor IF-2 associated region Arf PF00025.21 ETZ06964.1 - 0.0058 16.1 0.1 0.0058 16.1 0.1 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1_Xtn PF16897.5 ETZ06964.1 - 0.014 15.4 0.8 0.25 11.4 0.3 2.7 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain SIS_2 PF13580.6 ETZ06964.1 - 0.1 12.6 0.4 0.45 10.5 0.3 2.1 2 0 0 2 2 2 0 SIS domain DUF4741 PF15897.5 ETZ06964.1 - 0.97 9.2 2.7 1.9 8.3 2.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4741) Dynamin_N PF00350.23 ETZ06964.1 - 1.5 8.8 11.6 4.1 7.4 0.1 4.5 4 1 1 5 5 5 0 Dynamin family Pribosyltran PF00156.27 ETZ06965.1 - 6.2e-07 29.1 0.0 1.2e-06 28.1 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 ETZ06965.1 - 0.0053 16.3 0.0 0.0094 15.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase NMD3 PF04981.13 ETZ06965.1 - 0.011 15.2 5.7 0.85 9.0 0.3 2.4 2 0 0 2 2 2 0 NMD3 family zf-C2H2_11 PF16622.5 ETZ06965.1 - 0.012 15.3 0.1 0.43 10.4 0.0 2.8 2 0 0 2 2 2 0 zinc-finger C2H2-type PRTase_3 PF15610.6 ETZ06965.1 - 0.026 13.8 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 PRTase ComF-like zf-A20 PF01754.16 ETZ06965.1 - 0.049 13.6 3.3 2.7 8.0 0.1 2.6 2 0 0 2 2 2 0 A20-like zinc finger RdDM_RDM1 PF09187.10 ETZ06965.1 - 0.11 12.6 0.0 0.29 11.2 0.0 1.8 2 0 0 2 2 2 0 RNA-directed DNA methylation 1 OpcA_G6PD_assem PF10128.9 ETZ06965.1 - 0.14 11.7 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase subunit zinc-ribbons_6 PF07191.12 ETZ06965.1 - 0.19 11.7 5.1 2.7 8.0 0.3 2.4 1 1 1 2 2 2 0 zinc-ribbons zf-C2H2_4 PF13894.6 ETZ06965.1 - 2.4 9.2 7.9 24 6.1 0.0 4.0 3 1 0 3 3 3 0 C2H2-type zinc finger Prok-RING_4 PF14447.6 ETZ06965.1 - 3.8 7.4 11.1 0.3 11.0 1.3 2.9 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 DZR PF12773.7 ETZ06965.1 - 4.6 7.4 9.8 0.63 10.1 3.6 2.4 2 1 1 3 3 3 0 Double zinc ribbon DNA_pol_A_exo1 PF01612.20 ETZ06966.1 - 3.9e-29 101.6 0.0 4.9e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease HTH_Tnp_IS630 PF01710.16 ETZ06967.1 - 5e-12 45.9 0.4 6.5e-12 45.5 0.4 1.1 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 ETZ06967.1 - 0.00017 21.3 0.4 0.026 14.3 0.1 2.1 2 0 0 2 2 2 2 Homeodomain-like domain HTH_28 PF13518.6 ETZ06967.1 - 0.00084 19.4 1.2 0.014 15.5 0.2 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_10 PF04967.12 ETZ06967.1 - 0.038 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 HTH DNA binding domain CENP-B_N PF04218.13 ETZ06967.1 - 0.055 13.1 0.5 2.7 7.7 0.0 2.4 2 1 0 2 2 2 0 CENP-B N-terminal DNA-binding domain PAX PF00292.18 ETZ06967.1 - 0.065 13.2 0.0 0.1 12.5 0.0 1.3 1 1 0 1 1 1 0 'Paired box' domain DDE_3 PF13358.6 ETZ06968.1 - 3.4e-09 36.6 0.0 3.6e-09 36.5 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Kdo_hydroxy PF11004.8 ETZ06968.1 - 0.075 12.3 0.0 0.085 12.1 0.0 1.0 1 0 0 1 1 1 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase ILEI PF15711.5 ETZ06968.1 - 0.11 13.0 0.0 0.14 12.7 0.0 1.2 1 0 0 1 1 1 0 Interleukin-like EMT inducer YajC PF02699.15 ETZ06969.1 - 5.3e-21 74.3 0.5 6.2e-21 74.1 0.5 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Orf78 PF06024.12 ETZ06969.1 - 0.0088 16.3 0.1 0.012 15.9 0.1 1.2 1 0 0 1 1 1 1 Orf78 (ac78) P53_C PF11619.8 ETZ06969.1 - 0.63 10.1 2.9 19 5.4 0.1 2.2 1 1 1 2 2 2 0 Transcription factor P53 - C terminal domain Dala_Dala_lig_C PF07478.13 ETZ06970.1 - 5.2e-53 179.6 0.0 6.5e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 ETZ06970.1 - 1.1e-16 61.1 0.0 2.5e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase N-terminus ATP-grasp PF02222.22 ETZ06970.1 - 1.8e-05 24.4 0.1 4.4e-05 23.1 0.1 1.7 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 ETZ06970.1 - 0.0049 16.5 0.1 0.049 13.2 0.1 2.1 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 ETZ06970.1 - 0.028 14.2 0.1 0.042 13.6 0.1 1.2 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF917 PF06032.12 ETZ06970.1 - 0.072 11.9 0.1 0.14 10.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF917) TTL PF03133.15 ETZ06970.1 - 0.082 12.0 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Tubulin-tyrosine ligase family CPSase_L_D2 PF02786.17 ETZ06970.1 - 0.22 11.0 0.4 1.1 8.7 0.4 1.9 1 1 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Ins_beta PF03488.14 ETZ06970.1 - 2.1 8.4 6.5 11 6.1 0.0 3.4 4 0 0 4 4 4 0 Nematode insulin-related peptide beta type Mur_ligase_M PF08245.12 ETZ06971.1 - 4.3e-31 108.4 0.0 5.4e-27 95.0 0.0 2.3 1 1 1 2 2 2 2 Mur ligase middle domain Mur_ligase_C PF02875.21 ETZ06971.1 - 3.4e-18 65.7 0.0 6.7e-17 61.5 0.0 2.3 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain BolA PF01722.18 ETZ06972.1 - 2.6e-13 50.0 0.6 3e-13 49.8 0.6 1.1 1 0 0 1 1 1 1 BolA-like protein SAICAR_synt PF01259.18 ETZ06973.1 - 2.1e-07 30.8 0.0 3.4e-07 30.2 0.0 1.3 1 1 0 1 1 1 1 SAICAR synthetase PseudoU_synth_2 PF00849.22 ETZ06974.1 - 7e-29 101.0 0.0 9.9e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 ETZ06974.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 S4 domain DUF3050 PF11251.8 ETZ06975.1 - 0.18 11.4 5.9 6.1 6.4 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3050) SecA_DEAD PF07517.14 ETZ06976.1 - 3.7e-128 426.9 0.6 7.8e-128 425.8 0.6 1.5 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_SW PF07516.13 ETZ06976.1 - 1.3e-49 169.0 11.7 2.5e-49 168.0 8.4 2.6 2 0 0 2 2 2 1 SecA Wing and Scaffold domain SecA_PP_bind PF01043.20 ETZ06976.1 - 2.3e-35 121.6 0.4 7.5e-35 120.0 0.4 2.0 1 0 0 1 1 1 1 SecA preprotein cross-linking domain SEC-C PF02810.15 ETZ06976.1 - 6.2e-07 29.2 9.5 1.1e-06 28.5 9.5 1.4 1 0 0 1 1 1 1 SEC-C motif DEAD PF00270.29 ETZ06976.1 - 0.0004 20.2 0.0 0.0028 17.5 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF919 PF06034.11 ETZ06976.1 - 0.0077 16.0 2.2 0.031 14.1 2.2 2.0 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF919) Helicase_C PF00271.31 ETZ06976.1 - 0.11 12.8 3.3 0.12 12.8 0.0 2.7 3 0 0 3 3 3 0 Helicase conserved C-terminal domain Exonuc_VII_S PF02609.16 ETZ06976.1 - 0.92 9.6 3.4 0.95 9.6 0.8 2.5 2 0 0 2 2 2 0 Exonuclease VII small subunit DUF5398 PF17376.2 ETZ06976.1 - 7 7.3 7.4 4.1 8.1 0.1 4.1 4 0 0 4 4 4 0 Family of unknown function (DUF5398) RNase_HII PF01351.18 ETZ06977.1 - 1.9e-30 106.2 0.0 2.3e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII SmpA_OmlA PF04355.13 ETZ06978.1 - 1.1e-09 38.0 0.0 1.5e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 SmpA / OmlA family IN_DBD_C PF00552.21 ETZ06978.1 - 0.13 11.6 0.0 0.3 10.4 0.0 1.6 1 0 0 1 1 1 0 Integrase DNA binding domain Phage_integrase PF00589.22 ETZ06979.1 - 1.4e-29 103.1 0.0 2.4e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 ETZ06979.1 - 1.8e-08 34.5 0.7 1.8e-08 34.5 0.7 2.0 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Integrase_1 PF12835.7 ETZ06979.1 - 4.3e-05 23.7 0.0 0.00053 20.1 0.0 2.2 2 0 0 2 2 2 1 Integrase Phage_int_SAM_4 PF13495.6 ETZ06979.1 - 6.1e-05 23.4 1.6 6.1e-05 23.4 1.6 2.0 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain DIMCO_N PF16844.5 ETZ06979.1 - 0.057 13.7 0.0 0.23 11.8 0.0 1.9 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor, N-terminal Phage_lysozyme PF00959.19 ETZ06979.1 - 0.073 13.5 0.1 0.13 12.7 0.1 1.4 1 0 0 1 1 1 0 Phage lysozyme TP53IP5 PF15331.6 ETZ06979.1 - 0.092 12.9 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 PriA_C PF18074.1 ETZ06980.1 - 2.9e-20 72.9 0.2 7.3e-20 71.6 0.0 1.8 2 0 0 2 2 2 1 Primosomal protein N C-terminal domain PriA_3primeBD PF17764.1 ETZ06980.1 - 3.3e-13 49.3 0.0 1.3e-12 47.5 0.0 2.0 2 0 0 2 2 2 1 3′ DNA-binding domain (3′BD) DEAD PF00270.29 ETZ06980.1 - 3.1e-12 46.6 0.0 9.4e-12 45.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 ETZ06980.1 - 3e-11 43.6 0.0 5.6e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ETZ06980.1 - 1e-09 38.7 0.0 1.8e-05 25.0 0.0 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain PriA_CRR PF18319.1 ETZ06980.1 - 1.2e-06 28.4 2.5 1.2e-06 28.4 2.5 2.6 2 0 0 2 2 2 1 PriA DNA helicase Cys-rich region (CRR) domain SNF2_N PF00176.23 ETZ06980.1 - 0.013 14.3 0.1 0.023 13.4 0.1 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain Thioredoxin_2 PF13098.6 ETZ06980.1 - 0.09 13.2 0.0 5.3 7.5 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin-like domain DDE_Tnp_4 PF13359.6 ETZ06981.1 - 1e-05 25.3 0.3 1.1e-05 25.1 0.3 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease MRP-S22 PF10245.9 ETZ06981.1 - 0.0031 17.3 1.8 0.0033 17.2 1.8 1.0 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S22 Ribul_P_3_epim PF00834.19 ETZ06982.1 - 1.6e-44 151.7 0.0 1.9e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family LacAB_rpiB PF02502.18 ETZ06983.1 - 1.8e-31 109.0 0.0 2e-31 108.9 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Topoisom_bac PF01131.20 ETZ06984.1 - 4.9e-118 394.7 0.1 4.9e-118 394.7 0.1 2.0 2 0 0 2 2 2 1 DNA topoisomerase Toprim PF01751.22 ETZ06984.1 - 6.3e-23 81.0 3.1 8.6e-23 80.5 0.1 2.8 3 0 0 3 3 3 1 Toprim domain Toprim_C_rpt PF13368.6 ETZ06984.1 - 2.6e-20 72.2 0.0 2.1e-12 46.8 0.0 3.2 2 1 1 3 3 3 2 Topoisomerase C-terminal repeat zf-C4_Topoisom PF01396.19 ETZ06984.1 - 2.1e-09 37.0 2.5 2.1e-09 37.0 2.5 2.4 2 0 0 2 2 2 1 Topoisomerase DNA binding C4 zinc finger Toprim_4 PF13662.6 ETZ06984.1 - 0.0036 17.7 0.6 0.018 15.5 0.1 2.5 2 1 0 2 2 2 1 Toprim domain DNA_processg_A PF02481.15 ETZ06985.1 - 5.1e-68 228.5 0.0 7e-68 228.0 0.0 1.1 1 0 0 1 1 1 1 DNA recombination-mediator protein A DprA_WH PF17782.1 ETZ06985.1 - 6.8e-07 29.3 0.0 1.5e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 DprA winged helix domain DUF1641 PF07849.11 ETZ06985.1 - 0.023 14.6 0.1 0.15 12.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1641) Ribosomal_S4 PF00163.19 ETZ06986.1 - 1.2e-15 58.1 0.9 2.1e-15 57.4 0.9 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 ETZ06986.1 - 3.8e-11 42.5 0.0 7.1e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 S4 domain RmuC PF02646.16 ETZ06988.1 - 2.6e-78 263.1 0.7 4.1e-78 262.4 0.7 1.2 1 0 0 1 1 1 1 RmuC family IZUMO PF15005.6 ETZ06988.1 - 0.11 13.0 9.3 0.26 11.8 1.0 3.0 3 0 0 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated ExsD PF16806.5 ETZ06988.1 - 0.45 10.4 9.3 0.09 12.7 0.6 2.7 2 1 1 3 3 3 0 Antiactivator protein ExsD I_LWEQ PF01608.17 ETZ06988.1 - 2.1 8.5 8.8 0.64 10.2 0.4 2.9 3 1 1 4 4 4 0 I/LWEQ domain DUF4096 PF13340.6 ETZ06989.1 - 0.0018 18.4 0.0 0.0023 18.1 0.0 1.2 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) AAA_18 PF13238.6 ETZ06991.1 - 4.6e-09 36.9 0.0 6e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain Guanylate_kin PF00625.21 ETZ06991.1 - 0.00092 18.9 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 ETZ06991.1 - 0.0055 16.9 0.0 0.011 15.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ETZ06991.1 - 0.028 14.4 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Thymidylate_kin PF02223.17 ETZ06991.1 - 0.03 14.0 0.6 3.1 7.4 0.1 2.1 1 1 1 2 2 2 0 Thymidylate kinase AAA_17 PF13207.6 ETZ06991.1 - 0.048 14.1 0.1 4.5 7.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Rubrerythrin PF02915.17 ETZ06992.1 - 2.8e-26 92.6 1.5 5.6e-26 91.6 1.5 1.5 1 1 0 1 1 1 1 Rubrerythrin Ferritin PF00210.24 ETZ06992.1 - 2.8e-07 30.6 0.2 0.018 15.0 0.0 2.1 1 1 1 2 2 2 2 Ferritin-like domain ketoacyl-synt PF00109.26 ETZ06993.1 - 2.2e-52 178.2 0.0 3.6e-52 177.4 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 ETZ06993.1 - 1.1e-35 122.2 0.0 2.1e-35 121.3 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 ETZ06993.1 - 0.028 13.8 0.6 0.053 12.9 0.6 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 ETZ06993.1 - 0.099 13.1 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 ETZ06994.1 - 1e-09 38.6 0.2 1.3e-09 38.3 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 ETZ06994.1 - 0.00014 22.0 0.2 0.0002 21.5 0.2 1.4 1 1 0 1 1 1 1 Acyl-carrier Ribosomal_L50 PF10501.9 ETZ06994.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.7 1 1 0 1 1 1 0 Ribosomal subunit 39S Tricorn_C1 PF14684.6 ETZ06995.1 - 9.9e-26 89.6 0.6 2.3e-25 88.5 0.6 1.7 1 0 0 1 1 1 1 Tricorn protease C1 domain Peptidase_S41 PF03572.18 ETZ06995.1 - 5.9e-23 81.2 0.0 1.4e-22 80.0 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 Tricorn_PDZ PF14685.6 ETZ06995.1 - 5e-06 26.4 0.0 1.2e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Tricorn protease PDZ domain PD40 PF07676.12 ETZ06995.1 - 0.0011 18.8 0.1 2 8.4 0.0 3.6 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Peptidase_S66C PF17676.1 ETZ06996.1 - 1.6e-24 86.8 0.0 2.4e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 LD-carboxypeptidase C-terminal domain Peptidase_S66 PF02016.15 ETZ06996.1 - 4e-22 78.6 0.0 6.4e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 LD-carboxypeptidase N-terminal domain H_PPase PF03030.16 ETZ06997.1 - 2.3e-246 819.5 38.5 2.7e-246 819.3 38.5 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase EMP70 PF02990.16 ETZ06997.1 - 0.051 12.2 0.8 0.11 11.2 0.8 1.5 1 0 0 1 1 1 0 Endomembrane protein 70 Ribosomal_S16 PF00886.19 ETZ06998.1 - 2.5e-18 65.9 0.0 3.4e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 Ribosomal_L13 PF00572.18 ETZ06999.1 - 7.5e-45 152.2 0.0 8.9e-45 152.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Ribosomal_S9 PF00380.19 ETZ07000.1 - 8.9e-41 139.2 0.0 1.1e-40 139.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosom_S12_S23 PF00164.25 ETZ07001.1 - 7.4e-39 131.9 0.6 8.7e-39 131.7 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S7 PF00177.21 ETZ07002.1 - 9e-59 197.4 0.7 1e-58 197.2 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Phage_TAC_12 PF12363.8 ETZ07002.1 - 0.049 14.0 0.0 0.17 12.3 0.0 1.7 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC UDG PF03167.19 ETZ07003.1 - 3.9e-34 117.9 0.0 5.1e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily rve PF00665.26 ETZ07005.1 - 8.8e-07 29.1 0.0 1e-06 28.9 0.0 1.2 1 1 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 ETZ07005.1 - 0.0027 18.0 0.0 0.0035 17.6 0.0 1.3 1 1 0 1 1 1 1 DDE domain DDE_Tnp_4 PF13359.6 ETZ07006.1 - 9.7e-07 28.6 0.1 1.1e-06 28.4 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DASH_Dad3 PF08656.10 ETZ07007.1 - 1.4 9.0 7.5 4.9 7.3 5.0 3.3 2 1 0 2 2 2 0 DASH complex subunit Dad3 COX16 PF14138.6 ETZ07007.1 - 1.7 9.2 5.2 0.96 10.0 1.1 2.8 3 0 0 3 3 3 0 Cytochrome c oxidase assembly protein COX16 GDYXXLXY PF14345.6 ETZ07009.1 - 1.2e-17 64.1 0.2 1.4e-17 63.9 0.2 1.0 1 0 0 1 1 1 1 GDYXXLXY protein DUF4401 PF14351.6 ETZ07010.1 - 2e-22 79.9 35.4 2.5e-22 79.6 35.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) SLATT_fungal PF18142.1 ETZ07010.1 - 0.0025 17.8 0.1 0.008 16.2 0.1 1.8 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain DUF2157 PF09925.9 ETZ07011.1 - 9.2e-20 70.9 11.2 9.2e-20 70.9 11.2 2.9 2 1 1 3 3 3 2 Predicted membrane protein (DUF2157) Lig_chan PF00060.26 ETZ07011.1 - 0.89 9.4 10.2 1.8e+02 1.9 10.2 2.7 1 1 0 1 1 1 0 Ligand-gated ion channel CitMHS_2 PF16980.5 ETZ07013.1 - 3.1e-94 316.2 20.6 3.9e-94 315.8 20.6 1.0 1 0 0 1 1 1 1 Putative citrate transport CitMHS PF03600.16 ETZ07013.1 - 1.3e-08 34.4 2.1 1.3e-08 34.4 2.1 2.5 1 1 1 2 2 2 2 Citrate transporter DUF1646 PF07854.12 ETZ07013.1 - 0.0014 18.1 4.2 0.013 14.9 0.2 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF1646) DUF5134 PF17197.4 ETZ07013.1 - 0.038 13.9 0.4 0.2 11.6 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5134) YdjM PF04307.14 ETZ07013.1 - 0.4 10.0 7.7 0.89 8.8 2.6 3.5 2 1 1 3 3 3 0 LexA-binding, inner membrane-associated putative hydrolase JmjN PF02375.17 ETZ07017.1 - 0.17 11.9 1.4 0.34 10.9 0.5 2.0 2 0 0 2 2 2 0 jmjN domain DUF3452 PF11934.8 ETZ07017.1 - 0.26 10.8 7.1 0.99 9.0 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) DUF2004 PF09406.10 ETZ07017.1 - 3.5 8.0 6.9 6.2 7.2 0.6 3.0 2 2 1 3 3 3 0 Protein of unknown function (DUF2004) HigB-like_toxin PF05015.13 ETZ07019.1 - 0.011 16.1 0.1 0.014 15.8 0.1 1.1 1 0 0 1 1 1 0 RelE-like toxin of type II toxin-antitoxin system HigB BPD_transp_1 PF00528.22 ETZ07020.1 - 2.7e-14 53.3 15.1 2.7e-14 53.3 15.1 2.3 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component PDR_CDR PF06422.12 ETZ07020.1 - 2.3 8.2 11.2 6.9 6.7 0.6 3.6 3 1 0 3 3 3 0 CDR ABC transporter GGA_N-GAT PF18308.1 ETZ07021.1 - 1.1 8.9 6.2 6.5 6.5 2.1 3.7 3 0 0 3 3 3 0 GGA N-GAT domain Curto_V2 PF07325.11 ETZ07021.1 - 2.6 7.9 9.8 3.2 7.7 1.4 3.7 3 0 0 3 3 3 0 Curtovirus V2 protein PSD4 PF07631.11 ETZ07021.1 - 3.8 8.0 6.2 1.4 9.5 0.1 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1592) rve_3 PF13683.6 ETZ07022.1 - 1.7e-05 24.5 0.1 3e-05 23.7 0.1 1.4 1 1 0 1 1 1 1 Integrase core domain rve_2 PF13333.6 ETZ07022.1 - 0.041 14.1 0.1 0.064 13.4 0.1 1.3 1 0 0 1 1 1 0 Integrase core domain DUF3958 PF13125.6 ETZ07022.1 - 0.049 13.8 1.2 0.075 13.2 0.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3958) DnaGprimase_HBD PF16730.5 ETZ07022.1 - 0.073 13.2 1.5 0.4 10.8 1.5 2.0 1 1 0 1 1 1 0 DnaG-primase C-terminal, helicase-binding domain TolA_bind_tri PF16331.5 ETZ07022.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation SMBP PF16785.5 ETZ07022.1 - 0.11 12.7 1.6 0.14 12.4 1.6 1.2 1 0 0 1 1 1 0 Small metal-binding protein HTH_AraC PF00165.23 ETZ07022.1 - 0.12 12.6 0.1 2.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family MscS_porin PF12795.7 ETZ07022.1 - 0.14 11.7 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain HTH_23 PF13384.6 ETZ07023.1 - 0.085 12.7 0.1 0.16 11.8 0.1 1.5 1 1 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 ETZ07023.1 - 0.097 12.8 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain BrkDBD PF09607.10 ETZ07023.1 - 0.16 11.7 1.2 0.27 11.0 0.3 1.8 2 1 0 2 2 2 0 Brinker DNA-binding domain Glyco_transf_25 PF01755.17 ETZ07024.1 - 1.7e-15 57.5 0.0 6.9e-12 45.6 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Methyltransf_25 PF13649.6 ETZ07025.1 - 4.3e-09 37.0 0.0 7e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETZ07025.1 - 2.2e-05 23.9 0.0 2.6e-05 23.7 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 ETZ07025.1 - 2.7e-05 24.8 0.0 4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 ETZ07025.1 - 6.6e-05 22.1 0.0 7.9e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 ETZ07025.1 - 0.00015 22.4 0.0 0.00025 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETZ07025.1 - 0.00028 20.7 0.0 0.00062 19.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ETZ07025.1 - 0.01 15.6 0.0 0.012 15.3 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 ETZ07025.1 - 0.019 15.1 0.0 0.029 14.5 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 ETZ07025.1 - 0.024 14.5 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_17 PF12692.7 ETZ07025.1 - 0.024 14.6 0.0 0.12 12.4 0.0 1.8 1 1 1 2 2 2 0 S-adenosyl-L-methionine methyltransferase Methyltransf_PK PF05891.12 ETZ07025.1 - 0.16 11.4 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Glyco_transf_25 PF01755.17 ETZ07026.1 - 8.2e-23 81.3 0.0 1.4e-22 80.6 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Glycos_transf_N PF04413.16 ETZ07028.1 - 1.5e-40 138.7 0.1 3e-40 137.7 0.1 1.5 1 0 0 1 1 1 1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Rhodanese PF00581.20 ETZ07030.1 - 2.7e-11 43.9 0.0 4.6e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain DUF2892 PF11127.8 ETZ07030.1 - 2.3e-09 37.2 1.5 3.3e-09 36.6 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2892) TauE PF01925.19 ETZ07031.1 - 1.2e-35 123.2 32.5 1.6e-35 122.9 32.5 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Lactamase_B PF00753.27 ETZ07032.1 - 3.6e-20 72.8 0.5 5e-20 72.4 0.5 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ETZ07032.1 - 0.00036 20.1 0.3 0.00057 19.4 0.3 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain MFS_1 PF07690.16 ETZ07033.1 - 9.1e-08 31.4 16.5 9.1e-08 31.4 16.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1761 PF08570.10 ETZ07033.1 - 2 8.7 13.8 0.21 11.8 6.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1761) MFS_1 PF07690.16 ETZ07034.1 - 2.6e-26 92.4 9.0 3.1e-26 92.2 9.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETZ07034.1 - 1.9e-11 43.5 3.4 2.4e-11 43.2 3.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 ETZ07034.1 - 1.2e-05 24.1 1.0 1.5e-05 23.8 1.0 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein TRI12 PF06609.13 ETZ07034.1 - 2.1e-05 23.1 0.1 2.4e-05 23.0 0.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 ETZ07034.1 - 0.00035 20.0 2.1 0.00045 19.6 2.1 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_5 PF05631.14 ETZ07034.1 - 0.00036 19.6 0.7 0.00036 19.6 0.7 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM Acyl_transf_3 PF01757.22 ETZ07034.1 - 0.0074 15.4 2.1 0.0072 15.4 2.1 1.2 1 0 0 1 1 1 1 Acyltransferase family 12TM_1 PF09847.9 ETZ07034.1 - 0.1 11.7 0.9 0.11 11.6 0.9 1.2 1 0 0 1 1 1 0 Membrane protein of 12 TMs MlaA PF04333.13 ETZ07035.1 - 1.4e-44 152.2 0.0 1.8e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 MlaA lipoprotein CDP-OH_P_transf PF01066.21 ETZ07036.1 - 8.6e-13 48.9 0.5 8.6e-13 48.9 0.5 2.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Peptidase_M22 PF00814.25 ETZ07037.1 - 1.2e-78 264.5 0.0 1.4e-78 264.3 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family tRNA-synt_1f PF01921.18 ETZ07038.1 - 1.3e-122 409.2 0.0 1.8e-122 408.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (K) tRNA-synt_1g PF09334.11 ETZ07038.1 - 0.00059 18.7 0.0 0.0011 17.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 ETZ07038.1 - 0.075 12.4 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain ABC1 PF03109.16 ETZ07039.1 - 2.2e-16 60.1 0.0 3.8e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 ETZ07039.1 - 8.7e-05 22.6 0.0 0.00023 21.2 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family DDE_Tnp_1 PF01609.21 ETZ07040.1 - 7.6e-10 38.8 4.4 2.4e-07 30.6 4.4 2.5 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 ETZ07040.1 - 1.7e-09 37.9 0.1 2.3e-09 37.5 0.1 1.2 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 ETZ07040.1 - 0.00049 20.1 0.0 0.00071 19.6 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 ETZ07040.1 - 0.031 13.9 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease RasGEF PF00617.19 ETZ07042.1 - 0.033 14.4 5.2 0.63 10.2 0.3 2.6 2 0 0 2 2 2 0 RasGEF domain SMK-1 PF04802.15 ETZ07043.1 - 0.0063 16.4 7.7 0.84 9.4 0.1 4.1 1 1 3 4 4 4 2 Component of IIS longevity pathway SMK-1 DUF4618 PF15397.6 ETZ07043.1 - 0.011 15.1 3.0 1.1 8.6 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) DUF1433 PF07252.11 ETZ07043.1 - 0.11 12.8 8.3 4.7 7.5 1.2 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF1433) KIAA1430 PF13879.6 ETZ07043.1 - 3.3 8.5 8.5 12 6.7 8.5 2.0 1 1 0 1 1 1 0 KIAA1430 homologue GIIM PF08388.11 ETZ07044.1 - 0.05 13.7 0.6 0.46 10.6 0.6 2.0 1 1 0 1 1 1 0 Group II intron, maturase-specific domain DEP PF00610.21 ETZ07044.1 - 0.092 12.8 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) TnpV PF14198.6 ETZ07045.1 - 0.00017 21.5 0.2 0.14 12.1 0.0 2.2 1 1 1 2 2 2 2 Transposon-encoded protein TnpV Mon1 PF03164.14 ETZ07045.1 - 0.0049 16.0 0.3 0.0053 15.9 0.3 1.2 1 0 0 1 1 1 1 Trafficking protein Mon1 Imm51 PF15595.6 ETZ07045.1 - 0.0071 16.3 1.1 0.45 10.5 0.0 2.9 1 1 2 3 3 3 1 Immunity protein 51 SAS4 PF15460.6 ETZ07045.1 - 0.0073 16.4 1.1 0.39 10.9 0.1 2.9 1 1 1 3 3 3 1 Something about silencing, SAS, complex subunit 4 MgtE_N PF03448.17 ETZ07045.1 - 0.06 13.9 1.5 16 6.1 0.1 3.1 2 1 1 3 3 3 0 MgtE intracellular N domain Muraidase PF11860.8 ETZ07045.1 - 0.062 13.5 0.5 17 5.6 0.4 2.6 1 1 1 2 2 2 0 N-acetylmuramidase DUF4606 PF15379.6 ETZ07045.1 - 0.082 13.2 2.0 1.2 9.4 0.2 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4606) ESCRT-II PF05871.12 ETZ07045.1 - 0.13 12.6 3.0 3.6 7.8 3.0 2.4 1 1 0 1 1 1 0 ESCRT-II complex subunit DDE_Tnp_1 PF01609.21 ETZ07048.1 - 4.2e-07 29.8 0.2 5e-07 29.6 0.2 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_4 PF13701.6 ETZ07048.1 - 0.029 12.6 0.6 0.03 12.6 0.6 1.0 1 0 0 1 1 1 0 Transposase DDE domain group 1 Pre-PUA PF17832.1 ETZ07048.1 - 0.061 14.0 0.5 0.074 13.8 0.5 1.1 1 0 0 1 1 1 0 Pre-PUA-like domain HTH_Tnp_IS630 PF01710.16 ETZ07049.1 - 6.4e-11 42.4 0.0 7.4e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 ETZ07049.1 - 3e-05 23.7 0.0 0.00015 21.4 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 ETZ07049.1 - 0.004 17.2 0.0 0.028 14.5 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_psq PF05225.16 ETZ07049.1 - 0.05 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_Tnp_ISL3 PF13542.6 ETZ07049.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_Tnp_1 PF01527.20 ETZ07049.1 - 0.14 12.5 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 Transposase DUF2284 PF10050.9 ETZ07050.1 - 0.042 13.6 2.9 0.061 13.1 0.5 2.0 2 0 0 2 2 2 0 Predicted metal-binding protein (DUF2284) ABC_tran PF00005.27 ETZ07051.1 - 6.7e-35 120.6 0.0 1.2e-34 119.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 ETZ07051.1 - 1.2e-16 61.2 17.8 1.7e-16 60.7 17.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 ETZ07051.1 - 5.3e-05 22.7 3.1 0.0011 18.4 1.1 2.7 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ETZ07051.1 - 0.0033 17.5 0.2 0.0098 16.0 0.1 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 ETZ07051.1 - 0.0072 16.7 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 ETZ07051.1 - 0.0072 16.2 0.4 4.3 7.0 0.2 2.4 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ETZ07051.1 - 0.026 14.4 0.1 0.052 13.5 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 ETZ07051.1 - 0.043 13.6 0.1 0.096 12.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 ETZ07051.1 - 0.068 12.8 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 ETZ07051.1 - 0.073 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_24 PF13479.6 ETZ07051.1 - 0.083 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 ETZ07051.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB GCV_T PF01571.21 ETZ07052.1 - 1.2e-06 28.2 0.0 1.7e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DDE_3 PF13358.6 ETZ07054.1 - 0.0025 17.6 0.0 0.0026 17.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease AroM PF07302.11 ETZ07054.1 - 0.066 12.6 0.0 0.069 12.5 0.0 1.0 1 0 0 1 1 1 0 AroM protein DDE_3 PF13358.6 ETZ07055.1 - 0.065 13.0 0.0 0.078 12.7 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease BLUF PF04940.12 ETZ07056.1 - 0.064 13.4 0.2 0.18 12.0 0.2 1.8 1 0 0 1 1 1 0 Sensors of blue-light using FAD Cauli_DNA-bind PF03310.13 ETZ07056.1 - 0.085 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein DDE_3 PF13358.6 ETZ07057.1 - 0.0059 16.4 0.0 0.006 16.4 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease ACCA PF03255.14 ETZ07058.1 - 9.9e-52 174.6 0.0 2.8e-51 173.2 0.0 1.7 2 0 0 2 2 2 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Carboxyl_trans PF01039.22 ETZ07058.1 - 3.7e-17 62.1 0.0 5.2e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 ETZ07058.1 - 0.0011 18.5 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 Malonate decarboxylase gamma subunit (MdcE) LIN52 PF10044.9 ETZ07059.1 - 0.019 15.6 4.3 0.053 14.2 0.1 3.2 2 2 1 3 3 3 0 Retinal tissue protein Fungal_TACC PF12709.7 ETZ07059.1 - 0.057 13.9 9.9 0.12 12.8 0.1 3.5 3 0 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins CPDase PF07823.11 ETZ07059.1 - 0.067 12.9 0.4 0.098 12.3 0.4 1.3 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein Succ_DH_flav_C PF02910.20 ETZ07059.1 - 0.12 12.3 0.1 25 4.9 0.0 2.7 2 0 0 2 2 2 0 Fumarate reductase flavoprotein C-term DASH_Dad4 PF08650.10 ETZ07059.1 - 0.18 11.8 1.4 25 4.9 0.1 3.3 4 0 0 4 4 4 0 DASH complex subunit Dad4 MTBP_N PF14918.6 ETZ07061.1 - 0.036 13.5 0.0 0.092 12.2 0.0 1.6 1 1 0 1 1 1 0 MDM2-binding DUF5060 PF16586.5 ETZ07061.1 - 0.11 12.9 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5060) DDE_Tnp_1 PF01609.21 ETZ07063.1 - 9.4e-13 48.3 0.1 1.6e-12 47.6 0.1 1.3 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_4 PF13701.6 ETZ07063.1 - 0.00042 18.7 0.2 0.0012 17.2 0.2 1.6 1 1 0 1 1 1 1 Transposase DDE domain group 1 DDE_Tnp_2 PF04693.12 ETZ07063.1 - 0.00078 18.8 0.1 0.00086 18.6 0.1 1.2 1 0 0 1 1 1 1 Archaeal putative transposase ISC1217 DDE_5 PF13546.6 ETZ07063.1 - 0.0031 16.9 0.0 0.0042 16.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease dCMP_cyt_deam_1 PF00383.23 ETZ07064.1 - 3.4e-09 36.5 0.4 4.4e-09 36.1 0.4 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 ETZ07064.1 - 0.00032 20.9 0.0 0.00043 20.5 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 ETZ07064.1 - 0.0018 17.9 0.2 0.0072 16.0 0.0 1.8 1 1 1 2 2 2 1 A distinct subfamily of CDD/CDA-like deaminases DUF678 PF05077.12 ETZ07064.1 - 0.0068 16.5 0.4 0.013 15.6 0.4 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF678) tRNA-synt_2b PF00587.25 ETZ07066.1 - 4.3e-34 118.0 0.0 9.4e-34 116.9 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 ETZ07066.1 - 7.6e-12 45.2 0.0 2e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain Mur_ligase_M PF08245.12 ETZ07067.1 - 7.4e-28 97.9 0.0 1.1e-27 97.2 0.0 1.3 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase PF01225.25 ETZ07067.1 - 2.2e-07 31.1 0.0 4.5e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Mur ligase family, catalytic domain Mur_ligase_C PF02875.21 ETZ07067.1 - 6.7e-07 29.5 0.0 1.4e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain PBSX_XtrA PF17356.2 ETZ07067.1 - 0.0019 18.0 0.1 0.034 14.0 0.1 2.3 2 0 0 2 2 2 1 Phage-like element PBSX protein XtrA AAA_18 PF13238.6 ETZ07069.1 - 2e-08 34.9 0.6 2.3e-07 31.4 0.5 2.2 1 1 0 1 1 1 1 AAA domain Guanylate_kin PF00625.21 ETZ07069.1 - 2.3e-06 27.4 1.3 4.7e-06 26.4 1.3 1.6 1 1 0 1 1 1 1 Guanylate kinase Thymidylate_kin PF02223.17 ETZ07069.1 - 5.3e-05 23.0 1.9 0.024 14.3 1.9 2.1 1 1 0 1 1 1 1 Thymidylate kinase AAA_5 PF07728.14 ETZ07069.1 - 0.013 15.5 0.0 0.028 14.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) PPK2 PF03976.14 ETZ07069.1 - 0.017 14.6 0.2 0.03 13.8 0.2 1.4 1 1 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) PRK PF00485.18 ETZ07069.1 - 0.052 13.3 0.2 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 ETZ07069.1 - 0.059 13.5 0.1 0.8 9.9 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 ETZ07069.1 - 0.11 12.9 0.1 0.24 11.8 0.0 1.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CoaE PF01121.20 ETZ07069.1 - 0.2 11.3 1.4 4.4 7.0 0.0 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_23 PF13476.6 ETZ07069.1 - 0.21 12.1 9.0 0.81 10.2 9.0 1.8 1 1 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 ETZ07069.1 - 0.34 10.6 1.7 6.9 6.3 0.1 2.5 2 2 0 2 2 2 0 Cytidylate kinase DUF4334 PF14232.6 ETZ07070.1 - 0.036 14.0 0.0 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4334) Noc2 PF03715.13 ETZ07072.1 - 0.023 13.9 1.2 0.032 13.5 1.2 1.2 1 0 0 1 1 1 0 Noc2p family Rol_Rep_N PF18106.1 ETZ07072.1 - 0.12 12.7 0.8 0.28 11.5 0.3 1.8 1 1 0 2 2 2 0 Rolling Circle replication initiation protein N-terminal domain SRP14 PF02290.15 ETZ07073.1 - 0.04 14.3 1.1 0.13 12.6 0.3 2.4 2 1 0 2 2 2 0 Signal recognition particle 14kD protein GPR15L PF15854.5 ETZ07073.1 - 0.064 13.5 0.1 0.14 12.4 0.1 1.6 1 0 0 1 1 1 0 G-protein coupled receptor ligand 15 Ribosomal_L33 PF00471.20 ETZ07075.1 - 2.4e-10 40.7 1.2 2.4e-10 40.7 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 SBP_bac_5 PF00496.22 ETZ07076.1 - 1e-48 166.3 0.0 1.4e-48 165.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Ribosomal_S21 PF01165.20 ETZ07077.1 - 2.1e-13 49.7 6.7 2.1e-13 49.7 6.7 1.8 1 1 1 2 2 2 1 Ribosomal protein S21 tRNA-synt_1 PF00133.22 ETZ07078.1 - 3.2e-167 557.4 0.0 3.9e-167 557.2 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 ETZ07078.1 - 1.9e-21 76.3 0.3 5e-12 45.3 0.0 3.7 3 1 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 ETZ07078.1 - 1.2e-13 51.3 0.0 3.2e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 ETZ07078.1 - 6.7e-05 22.4 0.0 0.077 12.3 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.6 ETZ07078.1 - 0.0039 16.7 0.0 0.007 15.9 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1f PF01921.18 ETZ07078.1 - 0.0057 15.6 0.0 0.015 14.2 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (K) zf-FPG_IleRS PF06827.14 ETZ07078.1 - 0.18 11.7 4.3 0.39 10.6 4.3 1.6 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS Response_reg PF00072.24 ETZ07079.1 - 3.2e-11 43.4 0.0 2.3e-10 40.6 0.0 1.9 1 1 0 1 1 1 1 Response regulator receiver domain GTP_EFTU PF00009.27 ETZ07080.1 - 3e-70 235.7 0.0 5.1e-70 235.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 ETZ07080.1 - 2.5e-42 143.5 0.1 4.7e-42 142.6 0.1 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 ETZ07080.1 - 5.5e-34 116.1 0.0 1.1e-33 115.1 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 ETZ07080.1 - 6.7e-30 103.0 0.0 1.6e-29 101.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ETZ07080.1 - 7.8e-16 58.2 0.3 3.6e-15 56.1 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 ETZ07080.1 - 2.1e-07 30.8 0.0 1.9e-06 27.7 0.0 2.2 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 ETZ07080.1 - 9.1e-05 22.5 0.0 0.00028 21.0 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 ETZ07080.1 - 0.045 13.1 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 AIG1 family GRAS PF03514.14 ETZ07080.1 - 0.084 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 GRAS domain family Pro_Al_protease PF02983.14 ETZ07080.1 - 0.18 11.9 0.0 0.69 10.0 0.0 1.9 2 0 0 2 2 2 0 Alpha-lytic protease prodomain Methyltransf_31 PF13847.6 ETZ07081.1 - 2.2e-14 53.5 0.0 3.4e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ETZ07081.1 - 4.1e-12 46.0 0.0 1e-11 44.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 ETZ07081.1 - 1.8e-09 38.2 0.0 4.1e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 ETZ07081.1 - 5.8e-07 29.4 0.0 9.4e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_15 PF09445.10 ETZ07081.1 - 9.3e-07 28.6 0.0 1.4e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 ETZ07081.1 - 7e-06 25.6 0.0 9.8e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 ETZ07081.1 - 1.3e-05 24.9 0.0 3.2e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 ETZ07081.1 - 1.9e-05 25.2 0.0 4.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETZ07081.1 - 0.00025 21.7 0.0 0.00053 20.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 ETZ07081.1 - 0.00028 20.7 0.0 0.00063 19.5 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_18 PF12847.7 ETZ07081.1 - 0.0015 18.4 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_10 PF05971.12 ETZ07081.1 - 0.0036 16.7 0.0 0.0056 16.1 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase Methyltransf_23 PF13489.6 ETZ07081.1 - 0.0061 16.4 0.0 0.014 15.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 ETZ07081.1 - 0.0078 15.7 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.18 ETZ07081.1 - 0.02 14.2 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Eco57I PF07669.11 ETZ07081.1 - 0.13 12.7 0.0 0.31 11.6 0.0 1.6 1 0 0 1 1 1 0 Eco57I restriction-modification methylase Methyltransf_2 PF00891.18 ETZ07081.1 - 0.16 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_33 PF10017.9 ETZ07081.1 - 0.17 11.0 0.1 0.81 8.8 0.0 1.8 2 0 0 2 2 2 0 Histidine-specific methyltransferase, SAM-dependent N6_Mtase PF02384.16 ETZ07081.1 - 0.18 11.1 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase rRNA_methylase PF06962.12 ETZ07081.1 - 0.18 11.8 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative rRNA methylase HTH_Tnp_Tc5 PF03221.16 ETZ07081.1 - 0.21 11.7 1.0 1.3 9.1 0.1 2.4 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain B3_4 PF03483.17 ETZ07082.1 - 2.6e-22 79.3 0.0 1.5e-21 76.8 0.0 1.9 2 0 0 2 2 2 1 B3/4 domain tRNA_bind PF01588.20 ETZ07082.1 - 1.9e-14 53.5 0.1 3.2e-14 52.8 0.1 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain Ribosomal_L36 PF00444.18 ETZ07084.1 - 6.9e-08 32.6 3.1 1e-07 32.0 3.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L36 RNA_pol_Rpb6 PF01192.22 ETZ07085.1 - 1.7e-07 31.1 0.0 2.2e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 DNA_topoisoIV PF00521.20 ETZ07086.1 - 3.2e-142 474.4 0.1 6.1e-142 473.5 0.1 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 ETZ07086.1 - 2.1e-63 209.6 8.3 1.7e-12 46.6 0.2 6.6 7 0 0 7 7 7 6 DNA gyrase C-terminal domain, beta-propeller DUF2835 PF11197.8 ETZ07086.1 - 0.051 13.4 0.0 0.16 11.8 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2835) GIDA_assoc PF13932.6 ETZ07086.1 - 0.06 13.5 2.8 0.15 12.2 2.8 1.6 1 0 0 1 1 1 0 GidA associated domain TPD52 PF04201.15 ETZ07086.1 - 0.15 11.7 1.5 0.37 10.4 1.5 1.6 1 0 0 1 1 1 0 Tumour protein D52 family tRNA_NucTran2_2 PF13735.6 ETZ07086.1 - 0.15 12.0 3.1 0.41 10.6 3.1 1.7 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative ABC-3 PF00950.17 ETZ07087.1 - 5.6e-27 94.9 12.4 7.3e-27 94.5 12.4 1.1 1 0 0 1 1 1 1 ABC 3 transport family ZnuA PF01297.17 ETZ07087.1 - 2.8e-26 92.5 0.0 3.4e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic DUF4708 PF15813.5 ETZ07087.1 - 0.0012 18.1 0.9 0.0021 17.3 0.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4708) DUF1065 PF06358.11 ETZ07087.1 - 0.013 15.4 0.1 0.033 14.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1065) SfsA PF03749.13 ETZ07088.1 - 1.4e-40 138.4 0.0 1.8e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 Sugar fermentation stimulation protein RE domain SfsA_N PF17746.1 ETZ07088.1 - 6.2e-14 51.9 0.0 1.1e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 SfsA N-terminal OB domain Peptidase_M24 PF00557.24 ETZ07089.1 - 1.1e-49 169.0 0.0 1.2e-49 168.9 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3215 PF11503.8 ETZ07089.1 - 0.17 11.8 0.0 0.57 10.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3215) Aminotran_1_2 PF00155.21 ETZ07090.1 - 8e-61 206.2 0.0 9.1e-61 206.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 ETZ07090.1 - 5.9e-05 22.5 0.0 8e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 ETZ07090.1 - 0.00011 21.3 0.0 0.00018 20.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 ETZ07090.1 - 0.00053 18.6 0.0 0.00081 18.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Phenol_hyd_sub PF06099.11 ETZ07090.1 - 0.18 11.8 0.3 0.44 10.6 0.3 1.5 1 0 0 1 1 1 0 Phenol hydroxylase subunit HAD PF12710.7 ETZ07091.1 - 4.2e-06 27.3 0.2 0.00037 20.9 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ETZ07091.1 - 0.018 14.8 0.1 1.3 8.7 0.0 2.5 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ETZ07091.1 - 0.065 13.5 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase MazG PF03819.17 ETZ07092.1 - 0.00026 21.1 0.0 0.00078 19.6 0.0 1.8 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain PRA-PH PF01503.17 ETZ07092.1 - 0.0018 18.7 0.2 0.0037 17.7 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MgtE_N PF03448.17 ETZ07092.1 - 0.017 15.7 1.1 2.5 8.8 0.0 2.3 2 0 0 2 2 2 0 MgtE intracellular N domain DUF2059 PF09832.9 ETZ07092.1 - 0.059 13.4 1.1 0.16 12.1 0.0 2.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2059) Mannitol_dh PF01232.23 ETZ07092.1 - 0.11 12.7 0.7 0.17 12.1 0.7 1.4 1 1 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain NUC PF18510.1 ETZ07092.1 - 0.23 11.9 1.9 1.5 9.3 0.2 2.2 2 0 0 2 2 2 0 Nuclease domain Radical_SAM PF04055.21 ETZ07094.1 - 3.6e-14 53.5 0.0 6e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily HemN_C PF06969.16 ETZ07094.1 - 0.00014 21.8 1.0 0.00039 20.4 1.0 1.8 1 1 0 1 1 1 1 HemN C-terminal domain tRNA-synt_1g PF09334.11 ETZ07095.1 - 9.2e-102 340.7 1.2 7.1e-62 209.4 0.1 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 ETZ07095.1 - 6.5e-27 94.0 3.7 3.4e-18 65.3 0.1 3.9 1 1 3 4 4 4 4 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 ETZ07095.1 - 3.8e-14 52.7 0.0 5.8e-06 25.9 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain RE_Bpu10I PF09549.10 ETZ07097.1 - 0.0084 15.7 0.1 0.011 15.3 0.1 1.2 1 0 0 1 1 1 1 Bpu10I restriction endonuclease DNA_pol3_alpha PF07733.12 ETZ07098.1 - 1.2e-100 336.4 0.0 1.9e-100 335.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha NTPase domain DNA_pol3_finger PF17657.1 ETZ07098.1 - 2.7e-57 192.8 0.2 8.2e-57 191.2 0.1 2.0 2 0 0 2 2 2 1 Bacterial DNA polymerase III alpha subunit finger domain PHP PF02811.19 ETZ07098.1 - 4.9e-29 101.8 0.0 9.5e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 PHP domain HHH_6 PF14579.6 ETZ07098.1 - 3.7e-25 88.0 0.0 9.8e-25 86.6 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif tRNA_anti-codon PF01336.25 ETZ07098.1 - 6.9e-05 22.8 0.0 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain ABC_tran PF00005.27 ETZ07100.1 - 9.8e-29 100.6 0.0 1.6e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 ETZ07100.1 - 1.7e-09 37.8 5.5 2.6e-09 37.1 5.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 ETZ07100.1 - 5.7e-05 22.7 0.0 0.00015 21.3 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ETZ07100.1 - 8.7e-05 23.0 0.0 0.00018 22.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain cobW PF02492.19 ETZ07100.1 - 0.0048 16.5 0.1 0.0099 15.5 0.0 1.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 ETZ07100.1 - 0.0049 17.0 0.0 0.011 15.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 ETZ07100.1 - 0.03 14.6 0.0 0.18 12.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 ETZ07100.1 - 0.19 11.7 0.1 4.6 7.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NMN_transporter PF04973.12 ETZ07101.1 - 2.9e-11 43.6 6.1 3.1e-11 43.5 6.1 1.0 1 0 0 1 1 1 1 Nicotinamide mononucleotide transporter TK PF00265.18 ETZ07102.1 - 5.6e-50 169.7 0.4 6.4e-50 169.5 0.4 1.0 1 0 0 1 1 1 1 Thymidine kinase AAA_30 PF13604.6 ETZ07102.1 - 0.014 15.1 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 ETZ07102.1 - 0.065 13.5 0.1 0.096 13.0 0.1 1.5 1 1 0 1 1 1 0 AAA domain FAD_binding_7 PF03441.14 ETZ07103.1 - 1e-81 273.2 0.9 1.6e-81 272.6 0.9 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 ETZ07103.1 - 5.4e-32 111.1 0.0 9.7e-32 110.2 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase malic PF00390.19 ETZ07104.1 - 1.3e-20 74.0 0.1 1.3e-17 64.2 0.1 2.5 1 1 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 ETZ07104.1 - 8.1e-19 67.9 0.0 2.4e-18 66.4 0.0 1.7 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain MgtE PF01769.16 ETZ07105.1 - 6e-24 84.8 4.1 6e-24 84.8 4.1 1.6 2 0 0 2 2 2 1 Divalent cation transporter MgtE_N PF03448.17 ETZ07105.1 - 6.4e-14 52.4 0.4 1.3e-13 51.4 0.4 1.6 1 0 0 1 1 1 1 MgtE intracellular N domain CBS PF00571.28 ETZ07105.1 - 9.8e-10 38.7 0.5 3.6e-05 24.1 1.2 2.6 2 0 0 2 2 2 2 CBS domain Ribosomal_L35p PF01632.19 ETZ07106.1 - 4.9e-18 65.4 8.0 7.4e-18 64.8 8.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L35 Ribosomal_L20 PF00453.18 ETZ07107.1 - 7e-44 148.3 2.4 8.3e-44 148.1 2.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L20 DUF2312 PF10073.9 ETZ07108.1 - 1.3e-22 79.2 5.1 1.5e-22 79.0 5.1 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2312) Peptidase_M3_N PF08439.10 ETZ07108.1 - 0.091 13.0 2.1 6.7 7.1 0.5 2.3 2 1 0 2 2 2 0 Oligopeptidase F Abhydrolase_2 PF02230.16 ETZ07109.1 - 9.2e-19 68.1 0.0 1.3e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 ETZ07109.1 - 0.0019 17.5 0.1 0.03 13.6 0.1 2.4 1 1 1 2 2 2 1 Serine aminopeptidase, S33 FSH1 PF03959.13 ETZ07109.1 - 0.045 13.4 0.1 0.29 10.8 0.1 2.4 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 ETZ07109.1 - 0.077 13.6 0.2 0.099 13.2 0.2 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3089 PF11288.8 ETZ07109.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Abhydrolase_1 PF00561.20 ETZ07109.1 - 0.91 9.1 3.8 3 7.4 0.1 2.5 1 1 1 2 2 2 0 alpha/beta hydrolase fold DUF2380 PF09533.10 ETZ07111.1 - 6e-05 22.8 0.2 0.00011 21.9 0.2 1.4 1 0 0 1 1 1 1 Predicted lipoprotein of unknown function (DUF2380) DUF5565 PF17720.1 ETZ07111.1 - 0.015 14.2 0.7 0.023 13.6 0.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5565) PG_isomerase_N PF18353.1 ETZ07111.1 - 0.031 14.7 0.7 0.11 12.9 0.0 2.2 3 0 0 3 3 3 0 Phosphoglucose isomerase N-terminal domain CLN5 PF15014.6 ETZ07113.1 - 0.044 13.5 0.0 0.068 12.8 0.0 1.2 1 0 0 1 1 1 0 Ceroid-lipofuscinosis neuronal protein 5 RNase_T PF00929.24 ETZ07116.1 - 2.5e-29 103.0 0.0 4e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 ETZ07116.1 - 0.00032 20.7 0.0 0.00071 19.6 0.0 1.7 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like DNA_pol_A_exo1 PF01612.20 ETZ07116.1 - 0.01 15.6 0.0 0.14 11.9 0.0 2.3 1 1 0 1 1 1 0 3'-5' exonuclease TLC PF03219.14 ETZ07117.1 - 3.9e-148 494.2 13.9 4.6e-148 494.0 13.9 1.0 1 0 0 1 1 1 1 TLC ATP/ADP transporter PDR_CDR PF06422.12 ETZ07117.1 - 0.17 11.8 0.8 0.8 9.6 0.8 2.2 1 0 0 1 1 1 0 CDR ABC transporter DDE_Tnp_1 PF01609.21 ETZ07118.1 - 4.3e-12 46.1 0.3 5.4e-12 45.8 0.3 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_assoc PF13808.6 ETZ07119.1 - 6.1e-21 74.3 0.0 7e-21 74.1 0.0 1.0 1 0 0 1 1 1 1 DDE_Tnp_1-associated Glyco_transf_25 PF01755.17 ETZ07120.1 - 4.6e-22 78.9 0.0 1.2e-21 77.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Hfq PF17209.3 ETZ07121.1 - 7.9e-18 63.9 0.1 1.1e-17 63.4 0.1 1.1 1 0 0 1 1 1 1 Hfq protein Ran_BP1 PF00638.18 ETZ07121.1 - 0.19 12.0 0.0 0.35 11.1 0.0 1.5 2 0 0 2 2 2 0 RanBP1 domain HAD_2 PF13419.6 ETZ07122.1 - 2.6e-28 99.3 0.0 3.2e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ETZ07122.1 - 3.1e-10 40.7 0.0 1.8e-07 31.7 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ETZ07122.1 - 4.5e-09 37.0 0.0 6.7e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ETZ07122.1 - 0.00057 19.9 0.0 0.001 19.1 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like MraZ PF02381.18 ETZ07123.1 - 8.7e-20 70.5 0.0 1.6e-09 37.6 0.0 2.1 2 0 0 2 2 2 2 MraZ protein, putative antitoxin-like DUF2375 PF09558.10 ETZ07123.1 - 0.14 12.2 0.0 9.4 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2375) Methyltransf_5 PF01795.19 ETZ07124.1 - 3.1e-80 270.0 0.0 1.2e-79 268.1 0.0 1.7 1 1 0 1 1 1 1 MraW methylase family DUF3847 PF12958.7 ETZ07125.1 - 0.041 14.0 0.2 0.056 13.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) Jiraiya PF15038.6 ETZ07125.1 - 0.07 12.6 0.3 0.083 12.3 0.3 1.1 1 0 0 1 1 1 0 Jiraiya Asp_Glu_race PF01177.22 ETZ07126.1 - 1.1e-16 61.4 0.0 1.4e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Colicin_V PF02674.16 ETZ07127.1 - 3.1e-21 75.9 11.0 3.9e-21 75.5 11.0 1.1 1 0 0 1 1 1 1 Colicin V production protein DUF3742 PF12553.8 ETZ07127.1 - 3.8 7.6 4.3 1.5 8.9 1.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3742) Adeno_E3_CR2 PF02439.15 ETZ07127.1 - 9.8 6.0 9.0 8.7 6.2 1.9 2.4 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 rve PF00665.26 ETZ07128.1 - 1.8e-05 24.9 0.0 2.1e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain Sod_Ni PF09055.11 ETZ07129.1 - 0.037 14.6 4.7 2 9.0 0.0 4.2 4 0 0 4 4 4 0 Nickel-containing superoxide dismutase Plasmo_rep PF12135.8 ETZ07129.1 - 8.2 6.1 16.3 4.2 7.0 0.0 6.0 7 0 0 7 7 7 0 Plasmodium repeat family DDE_3 PF13358.6 ETZ07130.1 - 2.9e-17 62.8 0.3 3.3e-17 62.6 0.3 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.26 ETZ07130.1 - 0.012 15.8 0.0 0.016 15.4 0.0 1.2 1 0 0 1 1 1 0 Integrase core domain CNOT1_HEAT PF16418.5 ETZ07130.1 - 0.047 13.8 0.4 0.1 12.7 0.3 1.6 1 1 1 2 2 2 0 CCR4-NOT transcription complex subunit 1 HEAT repeat TTRAP PF14203.6 ETZ07134.1 - 0.11 12.5 0.4 0.18 11.8 0.4 1.3 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein DUF4096 PF13340.6 ETZ07135.1 - 4.6e-16 58.8 0.8 6e-16 58.4 0.8 1.1 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) APH PF01636.23 ETZ07137.1 - 1.7e-16 60.9 0.0 2.3e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ETZ07137.1 - 1.7e-06 27.8 0.0 2.7e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 ETZ07137.1 - 0.00055 19.4 0.0 0.00078 18.8 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 ETZ07137.1 - 0.021 14.4 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family EF-hand_12 PF17901.1 ETZ07137.1 - 0.036 14.5 0.0 0.13 12.8 0.0 1.9 2 0 0 2 2 2 0 EF-hand fold domain DUF4135 PF13575.6 ETZ07137.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Peptidase_S66 PF02016.15 ETZ07138.1 - 7.8e-29 100.3 0.0 1.2e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 LD-carboxypeptidase N-terminal domain Peptidase_S66C PF17676.1 ETZ07138.1 - 5.5e-27 94.8 0.0 1e-26 93.9 0.0 1.5 1 0 0 1 1 1 1 LD-carboxypeptidase C-terminal domain MarR PF01047.22 ETZ07138.1 - 0.15 12.0 0.0 1.4 8.9 0.0 2.5 3 0 0 3 3 3 0 MarR family Hairy_orange PF07527.13 ETZ07138.1 - 0.17 12.1 0.0 0.68 10.2 0.0 2.0 1 1 0 1 1 1 0 Hairy Orange HTH_24 PF13412.6 ETZ07139.1 - 1.5e-06 27.7 0.0 2.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 ETZ07139.1 - 0.00019 21.3 0.0 0.00036 20.4 0.0 1.4 1 0 0 1 1 1 1 MarR family MarR PF01047.22 ETZ07139.1 - 0.045 13.7 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 MarR family MIEAP PF16026.5 ETZ07139.1 - 0.061 13.5 0.0 0.12 12.6 0.0 1.5 1 1 0 1 1 1 0 Mitochondria-eating protein NusG PF02357.19 ETZ07140.1 - 5.7e-11 42.8 0.0 7.6e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Transcription termination factor nusG Polbeta PF18765.1 ETZ07141.1 - 1.1e-15 57.4 0.1 1.3e-15 57.2 0.1 1.1 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 ETZ07141.1 - 1.4e-09 38.1 0.0 1.6e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyltransferase domain MdcG PF10620.9 ETZ07141.1 - 0.24 11.2 0.0 0.26 11.0 0.0 1.1 1 0 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG NTase_sub_bind PF08780.11 ETZ07142.1 - 3.8e-33 114.1 0.0 4.1e-33 114.0 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyltransferase substrate binding protein like DUF86 PF01934.17 ETZ07142.1 - 0.093 12.6 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF86 ABC_tran PF00005.27 ETZ07143.1 - 2.5e-31 109.0 0.0 4.2e-31 108.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ETZ07143.1 - 4.7e-09 36.0 0.1 1.3e-05 24.7 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_membrane PF00664.23 ETZ07143.1 - 4.9e-07 29.7 14.0 7.2e-07 29.1 14.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_29 PF13555.6 ETZ07143.1 - 5.3e-05 22.9 0.1 0.00012 21.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 ETZ07143.1 - 0.00065 20.1 0.0 0.0014 19.0 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain DUF87 PF01935.17 ETZ07143.1 - 0.0013 18.9 0.0 0.0028 17.8 0.0 1.6 1 0 0 1 1 1 1 Helicase HerA, central domain T2SSE PF00437.20 ETZ07143.1 - 0.0022 17.1 0.0 0.0045 16.1 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein DEAD PF00270.29 ETZ07143.1 - 0.0022 17.8 0.0 0.0052 16.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_21 PF13304.6 ETZ07143.1 - 0.0028 17.5 0.6 0.25 11.1 0.2 2.3 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ETZ07143.1 - 0.0038 17.5 0.5 0.031 14.6 0.5 2.3 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 ETZ07143.1 - 0.0069 16.9 0.0 0.018 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ETZ07143.1 - 0.011 15.6 0.0 0.031 14.2 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase ABC_ATPase PF09818.9 ETZ07143.1 - 0.016 14.0 2.1 0.053 12.3 0.1 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class IstB_IS21 PF01695.17 ETZ07143.1 - 0.035 13.8 0.1 3.3 7.4 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein SbcCD_C PF13558.6 ETZ07143.1 - 0.045 14.0 0.6 0.34 11.2 0.6 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Microtub_bd PF16796.5 ETZ07143.1 - 0.052 13.5 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Microtubule binding MMR_HSR1 PF01926.23 ETZ07143.1 - 0.14 12.2 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase FixP_N PF14715.6 ETZ07143.1 - 1.5 8.6 3.6 27 4.6 1.1 2.5 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP GFO_IDH_MocA PF01408.22 ETZ07144.1 - 8.6e-20 71.8 0.2 2.3e-19 70.4 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Hexapep PF00132.24 ETZ07144.1 - 6.3e-18 63.7 15.3 3.9e-08 32.7 2.6 4.2 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 ETZ07144.1 - 5.9e-09 35.5 12.5 5.9e-05 22.7 0.7 4.2 3 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase F420_oxidored PF03807.17 ETZ07144.1 - 2.3e-05 24.9 0.1 7.6e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 ETZ07144.1 - 0.0015 18.7 0.0 0.003 17.7 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 ETZ07144.1 - 0.0049 16.5 0.0 0.0092 15.6 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 ETZ07144.1 - 0.0054 16.1 0.0 0.0093 15.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 ETZ07144.1 - 0.017 14.7 0.0 0.038 13.6 0.0 1.5 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Semialdhyde_dh PF01118.24 ETZ07144.1 - 0.031 14.7 0.0 0.084 13.3 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 ETZ07144.1 - 0.15 12.1 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DegT_DnrJ_EryC1 PF01041.17 ETZ07145.1 - 8.6e-109 364.1 0.0 9.7e-109 364.0 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 ETZ07145.1 - 8.9e-10 38.3 0.0 1.4e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ETZ07145.1 - 4.7e-05 22.8 0.0 9.4e-05 21.8 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 ETZ07145.1 - 0.062 12.3 0.0 0.092 11.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Epimerase PF01370.21 ETZ07146.1 - 1.7e-17 63.7 0.0 2.4e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ETZ07146.1 - 1.4e-05 24.4 0.0 1.4e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 ETZ07146.1 - 1.6e-05 24.5 0.0 2.8e-05 23.7 0.0 1.3 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 ETZ07146.1 - 0.06 13.2 0.0 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Hexapep PF00132.24 ETZ07147.1 - 2.6e-11 42.8 12.2 0.00019 21.0 0.1 4.5 4 1 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 ETZ07147.1 - 1.8e-06 27.6 15.3 0.0057 16.4 0.1 2.9 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Epimerase PF01370.21 ETZ07148.1 - 8.2e-54 182.6 0.0 9.7e-54 182.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ETZ07148.1 - 6.7e-50 170.4 0.0 8.6e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ETZ07148.1 - 3.2e-17 62.4 0.3 6.1e-17 61.5 0.3 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ETZ07148.1 - 6.5e-15 55.0 0.0 8.3e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 ETZ07148.1 - 2e-13 50.2 0.5 2.7e-12 46.4 0.4 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 ETZ07148.1 - 1.2e-12 47.5 0.6 1.5e-10 40.7 0.6 2.2 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 ETZ07148.1 - 1.1e-08 35.1 0.0 1.6e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 ETZ07148.1 - 3.7e-05 23.7 0.0 6.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 ETZ07148.1 - 0.00012 22.3 0.1 0.00032 21.0 0.1 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 ETZ07148.1 - 0.0077 16.5 0.1 0.019 15.2 0.0 1.7 2 0 0 2 2 2 1 TrkA-N domain adh_short PF00106.25 ETZ07148.1 - 0.01 15.3 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase NmrA PF05368.13 ETZ07148.1 - 0.043 13.4 0.1 0.33 10.5 0.1 2.1 2 0 0 2 2 2 0 NmrA-like family RHH_6 PF16762.5 ETZ07148.1 - 0.16 12.6 0.0 4.2 8.0 0.0 2.3 2 0 0 2 2 2 0 Ribbon-helix-helix domain Glycos_transf_1 PF00534.20 ETZ07149.1 - 9.7e-18 64.3 0.0 1.7e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ETZ07149.1 - 1.9e-13 51.0 0.0 3.7e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 ETZ07149.1 - 5.5e-05 23.5 0.0 0.00011 22.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ETZ07149.1 - 0.034 14.1 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Glyco_trans_4_2 PF13477.6 ETZ07149.1 - 0.13 12.3 1.1 0.28 11.2 0.3 2.0 2 0 0 2 2 2 0 Glycosyl transferase 4-like Lipase_GDSL PF00657.22 ETZ07150.1 - 1.4e-08 35.0 1.6 1.6e-08 34.8 1.6 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ETZ07150.1 - 0.00087 19.7 0.0 0.001 19.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family GATase PF00117.28 ETZ07151.1 - 3.3e-18 66.1 0.1 4e-18 65.9 0.1 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 ETZ07151.1 - 4.7e-12 46.2 0.1 1.2e-08 35.0 0.0 2.3 2 1 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 ETZ07151.1 - 1.6e-09 37.6 0.0 2.3e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 ETZ07151.1 - 0.0025 17.6 0.8 0.038 13.7 0.8 2.4 1 1 0 1 1 1 1 Peptidase C26 Peptidase_S51 PF03575.17 ETZ07151.1 - 0.072 12.7 0.0 0.09 12.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S51 His_biosynth PF00977.21 ETZ07152.1 - 6.3e-52 176.3 0.0 7.1e-52 176.1 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.17 ETZ07152.1 - 0.021 13.9 0.0 2.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) PcrB PF01884.17 ETZ07152.1 - 0.057 12.9 0.0 0.2 11.1 0.0 1.8 2 0 0 2 2 2 0 PcrB family TMP-TENI PF02581.17 ETZ07152.1 - 0.065 12.6 0.0 4 6.7 0.0 2.2 2 0 0 2 2 2 0 Thiamine monophosphate synthase NanE PF04131.14 ETZ07152.1 - 0.082 12.1 0.0 0.2 10.8 0.0 1.6 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase NAD_synthase PF02540.17 ETZ07153.1 - 1.3e-09 37.5 0.1 2.7e-09 36.5 0.0 1.5 2 0 0 2 2 2 1 NAD synthase ATP_bind_3 PF01171.20 ETZ07153.1 - 1.6e-05 24.7 0.0 3.9e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 PP-loop family QueC PF06508.13 ETZ07153.1 - 3.6e-05 23.4 0.2 0.00017 21.2 0.0 2.3 3 1 0 3 3 3 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 ETZ07153.1 - 0.00053 19.7 0.0 0.00086 19.1 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase NMD3 PF04981.13 ETZ07153.1 - 0.015 14.8 0.5 0.027 14.0 0.5 1.4 1 0 0 1 1 1 0 NMD3 family PAPS_reduct PF01507.19 ETZ07153.1 - 0.037 14.1 0.0 0.066 13.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Glyco_transf_4 PF13439.6 ETZ07154.1 - 4.1e-07 30.2 0.0 7.6e-07 29.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 ETZ07154.1 - 0.0031 18.0 0.0 0.008 16.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 ETZ07154.1 - 0.0045 17.4 0.0 0.01 16.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Chromo PF00385.24 ETZ07154.1 - 0.042 13.8 1.1 0.14 12.0 0.3 2.3 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Asn_synthase PF00733.21 ETZ07155.1 - 2.4e-87 293.9 0.0 2.9e-87 293.6 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 ETZ07155.1 - 3.1e-45 153.0 0.1 1.3e-44 151.1 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.6 ETZ07155.1 - 1.3e-40 138.7 0.0 2.4e-40 137.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 ETZ07155.1 - 0.00023 20.7 0.1 0.0023 17.4 0.0 2.2 2 1 0 2 2 2 1 Aluminium induced protein NAD_synthase PF02540.17 ETZ07155.1 - 0.061 12.4 0.0 0.13 11.3 0.0 1.6 1 0 0 1 1 1 0 NAD synthase Epimerase PF01370.21 ETZ07156.1 - 6.1e-42 143.7 0.0 8e-42 143.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ETZ07156.1 - 1.1e-37 130.2 0.0 3.6e-37 128.5 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 ETZ07156.1 - 1e-15 57.6 0.0 1.3e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 ETZ07156.1 - 4e-15 56.2 0.0 5.9e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 ETZ07156.1 - 1.6e-14 53.8 0.1 1.3e-13 50.8 0.1 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 ETZ07156.1 - 1.3e-12 47.3 0.0 1.7e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ETZ07156.1 - 4.4e-08 32.6 0.4 0.0025 17.0 0.0 2.5 1 1 1 2 2 2 2 Male sterility protein NAD_binding_3 PF03447.16 ETZ07156.1 - 0.00033 21.3 0.1 0.0017 19.0 0.0 1.9 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain adh_short PF00106.25 ETZ07156.1 - 0.0011 18.4 0.2 0.003 17.0 0.1 1.8 2 1 0 2 2 2 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 ETZ07156.1 - 0.0027 17.9 0.0 0.0041 17.4 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 ETZ07156.1 - 0.0061 16.1 0.0 0.016 14.7 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family DFP PF04127.15 ETZ07156.1 - 0.026 14.3 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein KR PF08659.10 ETZ07156.1 - 0.028 14.3 0.1 0.056 13.3 0.1 1.6 1 1 0 1 1 1 0 KR domain MAAL_N PF05034.13 ETZ07156.1 - 0.099 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase N-terminus F420_oxidored PF03807.17 ETZ07156.1 - 0.17 12.4 0.0 0.4 11.3 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 ETZ07157.1 - 3.3e-42 144.6 0.0 4.2e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ETZ07157.1 - 7.9e-31 107.7 0.1 3.7e-30 105.5 0.1 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ETZ07157.1 - 7.5e-13 48.1 0.2 1.7e-12 47.0 0.2 1.6 1 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 ETZ07157.1 - 1.8e-12 47.0 0.0 1.6e-11 43.9 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 ETZ07157.1 - 3.6e-07 30.2 0.0 5.5e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ETZ07157.1 - 5.8e-05 22.8 0.0 0.00011 21.8 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 ETZ07157.1 - 0.0004 19.6 0.1 0.03 13.5 0.0 2.2 1 1 1 2 2 2 1 Male sterility protein Sacchrp_dh_NADP PF03435.18 ETZ07157.1 - 0.0011 19.2 0.0 0.0019 18.4 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 ETZ07157.1 - 0.0058 16.9 0.0 0.0094 16.2 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain ThiF PF00899.21 ETZ07157.1 - 0.0085 15.5 0.3 0.03 13.7 0.1 1.8 2 0 0 2 2 2 1 ThiF family RmlD_sub_bind PF04321.17 ETZ07157.1 - 0.01 15.0 0.0 0.12 11.4 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain Ldh_1_N PF00056.23 ETZ07157.1 - 0.051 13.7 0.1 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 ETZ07157.1 - 0.052 14.0 0.0 0.097 13.1 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Semialdhyde_dh PF01118.24 ETZ07157.1 - 0.052 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase_2 PF02350.19 ETZ07158.1 - 1.3e-102 343.3 0.0 4.4e-102 341.5 0.0 1.7 1 1 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase Glyco_transf_28 PF03033.20 ETZ07158.1 - 0.037 14.1 0.0 0.064 13.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Glyco_trans_4_2 PF13477.6 ETZ07158.1 - 0.04 13.9 0.0 0.15 12.1 0.0 1.8 1 1 0 1 1 1 0 Glycosyl transferase 4-like Glyco_transf_4 PF13439.6 ETZ07158.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 ETZ07159.1 - 4.5e-05 23.8 0.0 9.1e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 HRXXH PF13933.6 ETZ07159.1 - 0.012 15.2 0.1 0.24 10.9 0.0 2.2 1 1 1 2 2 2 0 Putative peptidase family DUF1676 PF07898.13 ETZ07159.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) Fer2 PF00111.27 ETZ07162.1 - 1.5e-09 37.7 0.4 2.1e-09 37.2 0.4 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF2183 PF09949.9 ETZ07162.1 - 0.028 14.8 0.0 0.038 14.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) DAP_epimerase PF01678.19 ETZ07163.1 - 1.6e-14 54.1 0.0 3.5e-09 36.9 0.0 2.5 2 0 0 2 2 2 2 Diaminopimelate epimerase Meleagrin PF08189.11 ETZ07163.1 - 0.021 14.5 0.9 0.065 12.9 0.9 1.8 1 0 0 1 1 1 0 Meleagrin/Cygnin family Dus PF01207.17 ETZ07165.1 - 2.1e-85 286.6 0.0 2.5e-85 286.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) HATPase_c PF02518.26 ETZ07166.1 - 8.8e-16 58.4 0.0 1.8e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ETZ07166.1 - 2e-09 37.4 0.1 1.3e-08 34.7 0.0 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 ETZ07166.1 - 2.6e-05 24.1 0.0 6.9e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.6 ETZ07166.1 - 7.4e-05 22.6 0.0 0.00017 21.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 ETZ07166.1 - 0.0011 19.3 0.3 0.0033 17.8 0.0 2.0 2 0 0 2 2 2 1 HAMP domain RNase_T PF00929.24 ETZ07166.1 - 0.024 15.2 0.1 0.065 13.8 0.1 1.7 1 0 0 1 1 1 0 Exonuclease Sigma70_r1_1 PF03979.14 ETZ07166.1 - 0.04 14.0 1.8 0.39 10.8 0.2 2.9 3 0 0 3 3 3 0 Sigma-70 factor, region 1.1 DUF3671 PF12420.8 ETZ07166.1 - 0.59 10.2 11.9 0.066 13.3 1.6 2.8 2 1 1 3 3 3 0 Protein of unknown function Syntaxin-18_N PF10496.9 ETZ07167.1 - 0.02 15.1 0.5 0.068 13.4 0.5 1.9 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus DASH_Ask1 PF08655.10 ETZ07167.1 - 0.11 12.4 0.2 0.11 12.4 0.2 3.3 4 0 0 4 4 4 0 DASH complex subunit Ask1 Seryl_tRNA_N PF02403.22 ETZ07167.1 - 4.3 7.6 16.7 5.8 7.2 0.4 5.2 5 1 0 5 5 5 0 Seryl-tRNA synthetase N-terminal domain DUF1957 PF09210.11 ETZ07169.1 - 0.0011 19.3 0.1 0.0016 18.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1957) PYRIN PF02758.16 ETZ07169.1 - 0.077 13.1 1.8 0.14 12.3 1.8 1.3 1 0 0 1 1 1 0 PAAD/DAPIN/Pyrin domain S_100 PF01023.19 ETZ07169.1 - 3 7.6 6.8 0.18 11.5 1.7 1.6 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain NusB PF01029.18 ETZ07170.1 - 2.4e-15 56.9 0.0 2.7e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 NusB family Trypsin_2 PF13365.6 ETZ07171.1 - 5.9e-27 95.4 0.3 9e-27 94.8 0.3 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 ETZ07171.1 - 8.3e-20 70.9 3.7 7.4e-13 48.6 0.1 3.3 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 ETZ07171.1 - 3.3e-14 53.0 1.7 3.5e-11 43.3 0.1 3.0 2 1 1 3 3 3 2 PDZ domain PDZ_6 PF17820.1 ETZ07171.1 - 6.1e-13 48.4 0.6 2e-10 40.4 0.1 2.4 2 0 0 2 2 2 2 PDZ domain Trypsin PF00089.26 ETZ07171.1 - 3.8e-08 33.4 0.0 6.7e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Trypsin HlyD_3 PF13437.6 ETZ07171.1 - 2.2e-05 25.1 0.4 0.00054 20.6 0.0 2.7 3 0 0 3 3 3 1 HlyD family secretion protein DUF31 PF01732.16 ETZ07171.1 - 0.001 18.7 0.0 0.36 10.3 0.0 2.2 2 0 0 2 2 2 2 Putative peptidase (DUF31) Peptidase_S29 PF02907.15 ETZ07171.1 - 0.0034 17.1 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 Hepatitis C virus NS3 protease Tricorn_PDZ PF14685.6 ETZ07171.1 - 0.0052 16.7 0.3 0.074 13.0 0.1 2.4 2 0 0 2 2 2 1 Tricorn protease PDZ domain Peptidase_S46 PF10459.9 ETZ07171.1 - 0.12 11.0 0.9 0.37 9.4 0.2 1.9 2 0 0 2 2 2 0 Peptidase S46 DUF3394 PF11874.8 ETZ07171.1 - 0.15 11.8 0.2 19 4.9 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3394) ATP-synt_ab PF00006.25 ETZ07173.1 - 5.6e-73 245.1 0.0 8.4e-73 244.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 ETZ07173.1 - 1.6e-41 141.5 0.1 6.7e-41 139.6 0.0 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 ETZ07173.1 - 4.7e-14 52.7 1.2 1.4e-13 51.1 1.2 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt PF00231.19 ETZ07174.1 - 1.2e-51 176.1 0.2 1.4e-51 175.9 0.2 1.0 1 0 0 1 1 1 1 ATP synthase Jnk-SapK_ap_N PF09744.9 ETZ07174.1 - 0.84 9.8 9.3 0.37 11.0 2.6 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 UvrB_inter PF17757.1 ETZ07175.1 - 1.2e-29 102.3 0.0 3.6e-29 100.8 0.0 1.9 1 0 0 1 1 1 1 UvrB interaction domain Helicase_C PF00271.31 ETZ07175.1 - 1.7e-19 70.2 0.1 7.2e-19 68.2 0.1 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UvrB PF12344.8 ETZ07175.1 - 6.2e-17 61.2 0.0 1.4e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Ultra-violet resistance protein B ResIII PF04851.15 ETZ07175.1 - 2.7e-13 50.3 0.0 2.6e-12 47.1 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UVR PF02151.19 ETZ07175.1 - 1.7e-08 33.9 2.9 3.8e-08 32.8 1.3 2.6 2 0 0 2 2 2 1 UvrB/uvrC motif AAA_30 PF13604.6 ETZ07175.1 - 5.5e-06 26.2 0.0 0.00021 21.1 0.0 3.2 4 0 0 4 4 4 1 AAA domain DEAD PF00270.29 ETZ07175.1 - 8.7e-06 25.6 0.0 0.00028 20.7 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 ETZ07175.1 - 0.00041 20.1 0.0 0.0032 17.2 0.0 2.4 3 0 0 3 3 3 1 SWI2/SNF2 ATPase Microtub_bd PF16796.5 ETZ07175.1 - 0.00095 19.1 0.0 0.0028 17.6 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding Kinesin PF00225.23 ETZ07175.1 - 0.001 18.0 0.0 0.0025 16.8 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain AAA_7 PF12775.7 ETZ07175.1 - 0.0044 16.6 0.0 0.0085 15.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region UB2H PF14814.6 ETZ07175.1 - 0.008 16.2 0.0 0.027 14.5 0.0 2.0 1 0 0 1 1 1 1 Bifunctional transglycosylase second domain AAA_19 PF13245.6 ETZ07175.1 - 0.015 15.6 0.7 0.55 10.6 0.0 3.1 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 ETZ07175.1 - 0.031 14.5 0.1 0.31 11.3 0.0 2.7 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 ETZ07175.1 - 0.055 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 ETZ07175.1 - 0.058 13.8 0.2 0.57 10.5 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain AAA_5 PF07728.14 ETZ07175.1 - 0.09 12.8 0.0 0.42 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 ETZ07175.1 - 0.095 12.6 0.1 0.59 10.0 0.0 2.3 2 1 1 3 3 2 0 NACHT domain UvrD-helicase PF00580.21 ETZ07175.1 - 0.15 11.5 1.7 3.6 7.0 0.0 2.5 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF87 PF01935.17 ETZ07175.1 - 0.17 11.9 1.2 0.53 10.3 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain MutL_C PF08676.11 ETZ07176.1 - 5.5e-29 100.8 0.1 9.3e-29 100.1 0.1 1.4 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 ETZ07176.1 - 1.6e-27 95.5 0.0 3.3e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 ETZ07176.1 - 1.1e-12 47.9 0.0 2.1e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 ETZ07176.1 - 3.7e-08 33.9 0.0 9e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PapB PF03333.13 ETZ07177.1 - 0.014 15.4 0.3 0.081 13.0 0.0 2.3 2 0 0 2 2 2 0 Adhesin biosynthesis transcription regulatory protein Vps54_N PF10475.9 ETZ07177.1 - 0.29 10.4 14.9 0.42 9.8 1.6 2.9 3 1 0 3 3 3 0 Vacuolar-sorting protein 54, of GARP complex Spore_II_R PF09551.10 ETZ07177.1 - 0.7 10.3 10.7 3.1 8.3 0.1 3.9 3 1 0 3 3 3 0 Stage II sporulation protein R (spore_II_R) OEP PF02321.18 ETZ07178.1 - 4.9e-34 117.8 0.6 5.9e-16 58.8 0.5 2.2 2 0 0 2 2 2 2 Outer membrane efflux protein DUF3730 PF12530.8 ETZ07178.1 - 0.089 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3730) LRR_3 PF07725.12 ETZ07178.1 - 0.12 12.3 0.0 0.35 10.8 0.0 1.9 1 0 0 1 1 1 0 Leucine Rich Repeat DUF2497 PF10691.9 ETZ07179.1 - 0.15 12.5 3.8 0.9 10.0 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2497) BPL_LplA_LipB PF03099.19 ETZ07180.1 - 3.1e-09 36.8 0.0 4e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DDE_Tnp_IS1 PF03400.13 ETZ07182.1 - 0.00087 19.6 0.1 0.00094 19.5 0.1 1.0 1 0 0 1 1 1 1 IS1 transposase DDE_Tnp_IS240 PF13610.6 ETZ07182.1 - 0.0054 17.0 0.2 0.0064 16.7 0.2 1.1 1 0 0 1 1 1 1 DDE domain DUF4754 PF15946.5 ETZ07182.1 - 0.064 13.5 0.1 0.074 13.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4754) YqhG PF11079.8 ETZ07182.1 - 0.088 11.8 0.0 0.092 11.7 0.0 1.0 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function DDE_Tnp_IS1 PF03400.13 ETZ07183.1 - 0.00082 19.7 0.1 0.00093 19.5 0.1 1.1 1 0 0 1 1 1 1 IS1 transposase HTH_Tnp_4 PF13613.6 ETZ07186.1 - 7.8e-06 25.5 0.1 9.6e-06 25.2 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease ADK PF00406.22 ETZ07187.1 - 3.4e-35 121.4 0.0 4.3e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 ETZ07187.1 - 1.3e-18 67.7 0.1 2.4e-18 66.9 0.0 1.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ETZ07187.1 - 2.6e-07 31.3 0.0 6.5e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 ETZ07187.1 - 1.4e-06 28.1 2.0 0.095 12.4 0.1 3.1 1 1 2 3 3 3 2 Thymidylate kinase dNK PF01712.19 ETZ07187.1 - 0.0045 16.9 1.4 0.45 10.3 0.0 2.8 2 1 1 3 3 3 1 Deoxynucleoside kinase zf-CRD PF17979.1 ETZ07187.1 - 0.011 15.9 1.5 0.017 15.2 1.5 1.3 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions SKI PF01202.22 ETZ07187.1 - 0.022 14.9 0.1 0.22 11.6 0.1 2.5 1 1 0 1 1 1 0 Shikimate kinase AAA_33 PF13671.6 ETZ07187.1 - 0.063 13.4 0.1 0.25 11.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ETZ07187.1 - 0.081 13.2 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain SecY PF00344.20 ETZ07188.1 - 1.1e-84 284.3 17.1 1.4e-84 284.0 17.1 1.1 1 0 0 1 1 1 1 SecY translocase DUF2964 PF11177.8 ETZ07188.1 - 0.067 13.4 0.4 0.31 11.3 0.4 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2964) Ribosomal_L27A PF00828.19 ETZ07189.1 - 1.9e-30 106.2 0.3 2.3e-30 105.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L30 PF00327.20 ETZ07190.1 - 9.5e-14 51.0 0.5 1e-13 50.9 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_S5_C PF03719.15 ETZ07191.1 - 9.1e-28 95.5 0.1 1.5e-27 94.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 ETZ07191.1 - 2.8e-26 91.3 6.7 3.2e-26 91.1 5.5 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_L18p PF00861.22 ETZ07192.1 - 3.6e-40 137.0 0.5 4e-40 136.8 0.5 1.0 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast RraA-like PF03737.15 ETZ07192.1 - 0.056 13.6 0.0 0.067 13.4 0.0 1.2 1 0 0 1 1 1 0 Aldolase/RraA Ribosomal_L6 PF00347.23 ETZ07193.1 - 4.7e-11 43.2 0.1 1.5e-08 35.2 0.0 2.5 2 1 0 2 2 2 2 Ribosomal protein L6 Ribosomal_S8 PF00410.19 ETZ07194.1 - 1e-39 135.4 0.1 1.2e-39 135.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S8 YjhX_toxin PF09857.9 ETZ07194.1 - 0.027 14.4 0.1 0.55 10.2 0.1 2.2 1 1 0 1 1 1 0 Putative toxin of bacterial toxin-antitoxin pair Ribosomal_S14 PF00253.21 ETZ07195.1 - 1.1e-24 85.9 0.6 1.1e-24 85.9 0.6 1.5 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e Ribosomal_L5_C PF00673.21 ETZ07196.1 - 4.2e-34 116.6 0.0 6.1e-34 116.1 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 ETZ07196.1 - 1.4e-14 54.2 0.0 2e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L5 Endosulfine PF04667.17 ETZ07196.1 - 0.03 14.5 0.0 0.054 13.6 0.0 1.4 1 0 0 1 1 1 0 cAMP-regulated phosphoprotein/endosulfine conserved region ribosomal_L24 PF17136.4 ETZ07197.1 - 3.4e-15 56.2 0.0 6.1e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 ETZ07197.1 - 7.4e-07 28.9 1.4 1.8e-06 27.7 1.4 1.7 1 0 0 1 1 1 1 KOW motif Ribosomal_L14 PF00238.19 ETZ07198.1 - 2.4e-46 156.8 1.1 2.7e-46 156.6 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ribosomal_S17 PF00366.20 ETZ07199.1 - 4e-23 81.3 2.6 4.5e-23 81.1 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S17 DUF3335 PF11814.8 ETZ07199.1 - 0.1 12.1 1.1 0.099 12.1 1.1 1.0 1 0 0 1 1 1 0 Peptidase_C39 like family Ribosomal_L29 PF00831.23 ETZ07200.1 - 7.9e-11 41.8 2.6 9.8e-11 41.5 2.6 1.1 1 0 0 1 1 1 1 Ribosomal L29 protein zf-H3C2 PF16721.5 ETZ07200.1 - 0.057 13.8 0.3 0.059 13.7 0.3 1.1 1 0 0 1 1 1 0 Zinc-finger like, probable DNA-binding Ribosomal_L16 PF00252.18 ETZ07201.1 - 2.1e-42 144.2 0.2 2.4e-42 144.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_S3_C PF00189.20 ETZ07202.1 - 1.7e-32 111.8 0.2 2.6e-32 111.2 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 ETZ07202.1 - 4.9e-11 42.3 0.0 8.6e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 KH domain MRP-S24 PF14955.6 ETZ07202.1 - 0.037 14.0 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S24 GerPC PF10737.9 ETZ07202.1 - 0.17 11.9 0.0 0.27 11.3 0.0 1.2 1 0 0 1 1 1 0 Spore germination protein GerPC Ribosomal_L22 PF00237.19 ETZ07203.1 - 2.8e-19 69.2 0.0 3.2e-19 69.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_S19 PF00203.21 ETZ07204.1 - 9.1e-37 124.8 0.1 1e-36 124.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_L2_C PF03947.18 ETZ07205.1 - 1.8e-56 189.7 0.8 3.4e-56 188.9 0.8 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 ETZ07205.1 - 3e-20 72.0 0.0 9.1e-20 70.4 0.0 1.9 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_L23 PF00276.20 ETZ07206.1 - 2.6e-23 82.2 2.0 3.5e-23 81.8 2.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L23 Ribosomal_L4 PF00573.22 ETZ07207.1 - 3.4e-56 190.0 0.0 3.8e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_L3 PF00297.22 ETZ07208.1 - 4.5e-18 65.4 3.8 4.8e-17 62.0 0.9 2.4 2 1 1 3 3 3 2 Ribosomal protein L3 Ribosomal_S10 PF00338.22 ETZ07209.1 - 4e-23 81.5 0.0 4.6e-23 81.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e GTP_EFTU PF00009.27 ETZ07210.1 - 9.7e-62 208.0 0.1 1.3e-61 207.6 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 ETZ07210.1 - 1.6e-29 102.4 0.0 3e-29 101.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 ETZ07210.1 - 1.5e-17 63.7 8.7 1.5e-17 63.7 6.8 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ETZ07210.1 - 4.3e-05 23.6 0.0 8.6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ETZ07210.1 - 0.014 15.3 0.0 0.033 14.1 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase cobW PF02492.19 ETZ07210.1 - 0.019 14.5 0.5 0.045 13.3 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 ETZ07210.1 - 0.057 13.2 0.1 8.6 6.1 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 ETZ07210.1 - 0.18 11.5 0.3 4.9 6.9 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MFS_1 PF07690.16 ETZ07211.1 - 8.2e-32 110.5 44.2 1.3e-31 109.8 43.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily RBFA PF02033.18 ETZ07212.1 - 1.7e-14 54.2 0.9 1.8e-14 54.0 0.9 1.0 1 0 0 1 1 1 1 Ribosome-binding factor A p450 PF00067.22 ETZ07212.1 - 0.039 12.7 0.2 0.046 12.5 0.2 1.1 1 0 0 1 1 1 0 Cytochrome P450 DUF4265 PF14085.6 ETZ07212.1 - 0.072 13.1 0.1 0.093 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) GFO_IDH_MocA PF01408.22 ETZ07213.1 - 3.1e-20 73.2 0.3 4.5e-20 72.7 0.3 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.18 ETZ07213.1 - 0.0047 17.2 0.0 0.042 14.1 0.0 2.3 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_2 PF03446.15 ETZ07213.1 - 0.006 16.8 0.1 0.014 15.6 0.1 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase SmpA_OmlA PF04355.13 ETZ07214.1 - 0.0014 18.4 0.0 0.0019 17.9 0.0 1.2 1 0 0 1 1 1 1 SmpA / OmlA family CAP_assoc_N PF14504.6 ETZ07214.1 - 0.013 15.2 0.1 0.017 14.9 0.1 1.2 1 0 0 1 1 1 0 CAP-associated N-terminal GTP_EFTU PF00009.27 ETZ07215.1 - 6.6e-53 179.2 0.1 1e-52 178.5 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 ETZ07215.1 - 2.2e-48 162.9 0.6 4e-48 162.0 0.6 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 ETZ07215.1 - 3.7e-19 68.5 0.0 8.9e-19 67.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 ETZ07215.1 - 1.8e-08 34.3 0.0 6.1e-08 32.6 0.0 1.9 1 1 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 ETZ07215.1 - 1.1e-06 28.9 0.2 3.3e-06 27.4 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ETZ07215.1 - 3.8e-06 27.0 0.0 7.5e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 ETZ07215.1 - 8.7e-06 25.4 0.0 1.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Ras family FeoB_N PF02421.18 ETZ07215.1 - 0.00043 19.8 0.4 0.0015 18.1 0.4 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B Septin PF00735.18 ETZ07215.1 - 0.001 18.4 0.5 0.28 10.4 0.0 3.0 3 0 0 3 3 3 1 Septin RF3_C PF16658.5 ETZ07215.1 - 0.002 18.0 0.0 0.0042 16.9 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain AAA_23 PF13476.6 ETZ07215.1 - 0.0031 18.0 0.1 0.0063 17.0 0.0 1.5 2 0 0 2 2 1 1 AAA domain PduV-EutP PF10662.9 ETZ07215.1 - 0.0077 16.0 0.1 0.031 14.0 0.1 1.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 ETZ07215.1 - 0.009 16.2 0.0 0.024 14.8 0.0 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1_Xtn PF16897.5 ETZ07215.1 - 0.012 15.6 0.0 0.034 14.2 0.0 1.7 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain SRPRB PF09439.10 ETZ07215.1 - 0.041 13.3 0.0 0.075 12.5 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FtsJ PF01728.19 ETZ07216.1 - 3.2e-46 157.7 0.0 3.6e-46 157.5 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 ETZ07216.1 - 4.9e-07 29.6 0.0 3.5e-05 23.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETZ07216.1 - 0.00012 22.0 0.0 0.00025 20.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETZ07216.1 - 0.00051 20.7 0.2 0.0075 17.0 0.2 2.3 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ETZ07216.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltr_RsmB-F PF01189.17 ETZ07216.1 - 0.14 11.7 0.0 1.9 8.1 0.0 2.2 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F MMR_HSR1 PF01926.23 ETZ07217.1 - 6.4e-43 145.5 0.0 9.4e-23 80.5 0.0 2.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.6 ETZ07217.1 - 1.2e-23 83.2 0.1 2.4e-23 82.2 0.1 1.5 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.18 ETZ07217.1 - 1.1e-18 67.2 0.0 1.2e-08 34.7 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B Dynamin_N PF00350.23 ETZ07217.1 - 4.4e-16 59.4 0.2 9.6e-06 25.8 0.0 3.5 2 2 1 3 3 3 3 Dynamin family GTP_EFTU PF00009.27 ETZ07217.1 - 1.8e-11 43.9 0.0 0.0032 17.0 0.0 5.2 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 ETZ07217.1 - 1.4e-08 34.4 0.0 4.4e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 AIG1 family ABC_tran PF00005.27 ETZ07217.1 - 3.2e-06 27.7 0.1 0.024 15.2 0.0 2.6 2 1 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 ETZ07217.1 - 7.6e-06 25.9 0.0 0.13 12.2 0.0 3.3 3 0 0 3 3 3 2 RsgA GTPase Arf PF00025.21 ETZ07217.1 - 6.4e-05 22.5 0.0 0.27 10.7 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.6 ETZ07217.1 - 0.00019 21.1 0.1 0.89 9.3 0.0 3.6 3 0 0 3 3 3 1 P-loop containing region of AAA domain PduV-EutP PF10662.9 ETZ07217.1 - 0.00024 20.9 0.0 0.002 17.9 0.0 2.4 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 ETZ07217.1 - 0.00056 20.1 0.1 0.63 10.3 0.2 3.0 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 ETZ07217.1 - 0.0012 18.6 0.0 1.5 8.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain Septin PF00735.18 ETZ07217.1 - 0.0025 17.1 0.0 0.95 8.7 0.0 2.6 2 1 0 2 2 2 1 Septin Ras PF00071.22 ETZ07217.1 - 0.017 14.7 0.0 1 8.9 0.0 2.6 2 1 0 2 2 2 0 Ras family TniB PF05621.11 ETZ07217.1 - 0.019 14.3 0.1 2.3 7.6 0.0 2.6 3 0 0 3 3 3 0 Bacterial TniB protein AAA_22 PF13401.6 ETZ07217.1 - 0.02 15.2 0.7 11 6.3 0.0 3.2 2 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 ETZ07217.1 - 0.035 13.9 0.7 20 4.9 0.0 3.3 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein SRPRB PF09439.10 ETZ07217.1 - 0.039 13.4 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit FtsK_SpoIIIE PF01580.18 ETZ07217.1 - 0.045 13.1 0.0 0.4 10.0 0.0 2.3 3 0 0 3 3 3 0 FtsK/SpoIIIE family IIGP PF05049.13 ETZ07217.1 - 0.065 12.3 0.0 0.53 9.3 0.0 2.0 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) MeaB PF03308.16 ETZ07217.1 - 0.1 11.6 0.0 6.6 5.6 0.0 2.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PQQ_2 PF13360.6 ETZ07218.1 - 2.3e-34 119.0 0.0 3.4e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 PQQ-like domain PQQ_3 PF13570.6 ETZ07218.1 - 8e-12 45.3 0.1 0.015 15.8 0.1 5.3 5 0 0 5 5 5 3 PQQ-like domain PQQ PF01011.21 ETZ07218.1 - 9.1e-09 34.8 2.2 0.11 12.4 0.0 5.6 6 0 0 6 6 6 4 PQQ enzyme repeat TPR_21 PF09976.9 ETZ07219.1 - 0.024 14.3 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain ATP_bind_2 PF03668.15 ETZ07220.1 - 7e-70 235.5 0.0 7.9e-70 235.4 0.0 1.0 1 0 0 1 1 1 1 P-loop ATPase protein family AAA_22 PF13401.6 ETZ07220.1 - 0.0072 16.6 0.1 0.019 15.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 ETZ07220.1 - 0.012 14.8 0.0 1 8.6 0.0 2.5 3 0 0 3 3 3 0 Zeta toxin AAA_18 PF13238.6 ETZ07220.1 - 0.021 15.4 0.6 0.11 13.0 0.6 2.1 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.6 ETZ07220.1 - 0.027 14.3 0.0 0.045 13.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 ETZ07220.1 - 0.032 14.4 0.0 0.094 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ETZ07220.1 - 0.28 10.9 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain ROS_MUCR PF05443.11 ETZ07221.1 - 4e-39 133.5 0.0 4.7e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 ROS/MUCR transcriptional regulator protein Sigma70_r3 PF04539.16 ETZ07222.1 - 1.1e-23 83.1 0.2 6.3e-23 80.7 0.0 2.5 2 0 0 2 2 2 1 Sigma-70 region 3 Sigma70_r2 PF04542.14 ETZ07222.1 - 7.8e-22 76.8 0.5 1.6e-21 75.9 0.5 1.6 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 ETZ07222.1 - 1.6e-16 59.5 8.7 2.3e-16 59.0 3.4 3.5 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_r1_2 PF00140.20 ETZ07222.1 - 2.5e-14 53.0 0.8 7.1e-13 48.3 0.0 3.0 2 0 0 2 2 2 1 Sigma-70 factor, region 1.2 Sigma70_ner PF04546.13 ETZ07222.1 - 8.8e-11 42.1 16.3 3.5e-10 40.1 12.9 2.9 2 1 0 2 2 2 1 Sigma-70, non-essential region HTH_19 PF12844.7 ETZ07222.1 - 0.0037 17.3 0.6 0.72 9.9 0.0 4.1 4 0 0 4 4 4 1 Helix-turn-helix domain Cytokin-bind PF09265.10 ETZ07222.1 - 0.0056 16.1 0.1 0.0099 15.3 0.1 1.4 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding DUF4096 PF13340.6 ETZ07223.1 - 1.8e-06 28.0 0.2 2.5e-06 27.6 0.2 1.4 1 1 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) E1_dh PF00676.20 ETZ07224.1 - 9.8e-79 264.4 0.0 1.2e-78 264.1 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 ETZ07224.1 - 2.4e-06 27.0 0.1 6.2e-06 25.6 0.1 1.6 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 ETZ07224.1 - 0.00049 19.9 0.2 0.0029 17.4 0.2 2.1 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain HrcA PF01628.21 ETZ07225.1 - 6.5e-28 98.1 0.0 1e-27 97.5 0.0 1.2 1 0 0 1 1 1 1 HrcA protein C terminal domain HrcA_DNA-bdg PF03444.15 ETZ07225.1 - 0.0013 18.3 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Fe_dep_repress PF01325.19 ETZ07225.1 - 0.0018 18.4 0.0 0.011 16.0 0.0 2.1 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain Rrf2 PF02082.20 ETZ07225.1 - 0.022 15.1 0.0 0.063 13.6 0.0 1.7 2 0 0 2 2 2 0 Transcriptional regulator Penicillinase_R PF03965.16 ETZ07225.1 - 0.046 14.1 0.1 0.19 12.1 0.0 2.0 2 0 0 2 2 2 0 Penicillinase repressor GrpE PF01025.19 ETZ07226.1 - 4.7e-41 140.2 1.7 5.6e-41 140.0 1.7 1.1 1 0 0 1 1 1 1 GrpE AAA_25 PF13481.6 ETZ07227.1 - 1.5e-15 57.3 0.0 3.2e-15 56.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 ETZ07227.1 - 9e-15 54.6 0.1 3.6e-13 49.4 0.1 2.2 1 1 0 1 1 1 1 KaiC ChlI PF13541.6 ETZ07227.1 - 4.1e-08 33.1 0.1 2.4e-07 30.6 0.0 2.2 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.6 ETZ07227.1 - 3e-07 30.8 0.1 6.1e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 ETZ07227.1 - 5.5e-07 29.2 0.1 1.9e-06 27.5 0.1 1.8 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain Rubredoxin_2 PF18073.1 ETZ07227.1 - 2.7e-06 27.0 4.3 4.8e-06 26.2 4.3 1.4 1 0 0 1 1 1 1 Rubredoxin metal binding domain Lon_C PF05362.13 ETZ07227.1 - 1.6e-05 24.6 0.0 3.1e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 ETZ07227.1 - 3.1e-05 24.4 0.0 6.8e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ETZ07227.1 - 0.00012 22.5 0.0 0.00026 21.4 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Rad51 PF08423.11 ETZ07227.1 - 0.003 16.8 0.1 0.05 12.8 0.1 2.1 1 1 0 1 1 1 1 Rad51 AAA_19 PF13245.6 ETZ07227.1 - 0.0031 17.9 0.2 0.0057 17.0 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 ETZ07227.1 - 0.0031 17.3 0.0 0.023 14.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 ETZ07227.1 - 0.0031 16.8 0.1 0.0055 15.9 0.1 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain MCM PF00493.23 ETZ07227.1 - 0.0033 16.6 0.0 0.0067 15.6 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain NACHT PF05729.12 ETZ07227.1 - 0.0035 17.3 0.1 0.0079 16.1 0.1 1.7 1 1 0 1 1 1 1 NACHT domain NTPase_1 PF03266.15 ETZ07227.1 - 0.0065 16.4 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 NTPase AAA_29 PF13555.6 ETZ07227.1 - 0.011 15.4 0.2 0.039 13.7 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_5 PF07728.14 ETZ07227.1 - 0.014 15.4 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) GvpD PF07088.11 ETZ07227.1 - 0.016 13.9 0.1 0.058 12.0 0.1 1.8 1 1 0 1 1 1 0 GvpD gas vesicle protein AAA_30 PF13604.6 ETZ07227.1 - 0.017 14.8 0.1 0.03 14.0 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 ETZ07227.1 - 0.031 14.3 0.0 0.065 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 ETZ07227.1 - 0.069 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 ETZ07227.1 - 0.081 13.4 0.1 0.16 12.5 0.1 1.6 1 0 0 1 1 1 0 ABC transporter TPP_enzyme_N PF02776.18 ETZ07227.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Zeta_toxin PF06414.12 ETZ07227.1 - 0.17 11.1 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Ala_racemase_N PF01168.20 ETZ07228.1 - 3.1e-55 187.2 0.0 5.8e-55 186.3 0.0 1.4 2 0 0 2 2 2 1 Alanine racemase, N-terminal domain Ala_racemase_C PF00842.21 ETZ07228.1 - 1.6e-30 105.4 0.0 2.6e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, C-terminal domain CDP-OH_P_transf PF01066.21 ETZ07229.1 - 3.4e-11 43.8 0.7 3.4e-11 43.8 0.7 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF1067 PF06362.11 ETZ07229.1 - 0.19 12.5 0.0 0.3 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1067) AI-2E_transport PF01594.16 ETZ07230.1 - 2.7e-40 138.5 37.2 3.3e-40 138.2 37.2 1.0 1 0 0 1 1 1 1 AI-2E family transporter RuvB_N PF05496.12 ETZ07231.1 - 5.2e-72 240.8 0.0 7.2e-72 240.3 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RuvB_C PF05491.13 ETZ07231.1 - 1.2e-24 86.0 0.0 2.4e-24 85.0 0.0 1.6 1 0 0 1 1 1 1 RuvB C-terminal winged helix domain AAA_lid_4 PF17864.1 ETZ07231.1 - 8.9e-19 67.0 0.1 1.4e-18 66.4 0.1 1.3 1 0 0 1 1 1 1 RuvB AAA lid domain AAA PF00004.29 ETZ07231.1 - 5.9e-18 65.6 0.0 9.8e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ETZ07231.1 - 2.3e-10 40.6 0.1 3.6e-08 33.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 ETZ07231.1 - 4.2e-07 29.5 0.1 0.0001 21.7 0.0 2.5 3 0 0 3 3 3 1 TIP49 P-loop domain Sigma54_activat PF00158.26 ETZ07231.1 - 8.5e-07 28.8 0.0 0.019 14.7 0.0 2.3 1 1 1 2 2 2 2 Sigma-54 interaction domain AAA_3 PF07726.11 ETZ07231.1 - 2e-05 24.4 0.1 0.0014 18.4 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ETZ07231.1 - 4.7e-05 23.7 0.7 0.03 14.6 0.0 2.5 1 1 1 2 2 2 2 AAA domain RNA_helicase PF00910.22 ETZ07231.1 - 6.2e-05 23.3 0.0 0.00011 22.6 0.0 1.3 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.6 ETZ07231.1 - 7.3e-05 23.2 0.4 0.00065 20.1 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain ResIII PF04851.15 ETZ07231.1 - 0.00011 22.3 0.5 0.082 12.9 0.0 2.5 2 1 1 3 3 3 2 Type III restriction enzyme, res subunit AAA_14 PF13173.6 ETZ07231.1 - 0.00025 21.1 0.0 0.0009 19.3 0.0 1.9 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 ETZ07231.1 - 0.00025 20.5 2.4 0.17 11.2 0.4 2.9 2 1 0 3 3 3 2 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 ETZ07231.1 - 0.00041 20.3 0.1 0.014 15.3 0.0 2.5 2 1 1 3 3 2 1 NTPase DUF815 PF05673.13 ETZ07231.1 - 0.00061 19.0 0.1 0.18 10.9 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 ETZ07231.1 - 0.0019 18.4 0.0 0.0035 17.5 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain NB-ARC PF00931.22 ETZ07231.1 - 0.0025 17.0 0.0 0.0042 16.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TsaE PF02367.17 ETZ07231.1 - 0.0043 17.0 0.0 0.0077 16.2 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 ETZ07231.1 - 0.005 16.8 0.0 0.0088 16.0 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain Bac_DnaA PF00308.18 ETZ07231.1 - 0.0057 16.5 0.2 0.046 13.5 0.2 2.2 1 1 0 1 1 1 1 Bacterial dnaA protein IstB_IS21 PF01695.17 ETZ07231.1 - 0.0075 16.0 0.7 0.036 13.8 0.2 2.2 2 1 0 2 2 1 1 IstB-like ATP binding protein NACHT PF05729.12 ETZ07231.1 - 0.0082 16.1 0.0 0.023 14.6 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.6 ETZ07231.1 - 0.015 15.4 0.0 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 ETZ07231.1 - 0.022 15.1 0.4 0.44 10.9 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 ETZ07231.1 - 0.038 14.5 0.0 0.068 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 ETZ07231.1 - 0.055 12.9 0.2 0.69 9.3 0.0 2.1 1 1 1 2 2 2 0 Bacterial TniB protein MCM PF00493.23 ETZ07231.1 - 0.073 12.2 0.1 1.7 7.7 0.1 2.1 1 1 0 1 1 1 0 MCM P-loop domain AAA_30 PF13604.6 ETZ07231.1 - 0.085 12.6 0.1 0.43 10.3 0.0 1.9 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 ETZ07231.1 - 0.13 12.7 0.0 0.33 11.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_PrkA PF08298.11 ETZ07231.1 - 0.17 10.8 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain DDE_3 PF13358.6 ETZ07233.1 - 1.4e-21 76.8 0.1 1.5e-21 76.7 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.26 ETZ07233.1 - 3.4e-06 27.2 0.0 3.9e-06 27.1 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain DEDD_Tnp_IS110 PF01548.17 ETZ07233.1 - 0.13 12.1 0.0 0.15 11.9 0.0 1.0 1 0 0 1 1 1 0 Transposase HTH_Tnp_IS630 PF01710.16 ETZ07234.1 - 2e-20 73.0 0.3 2.4e-20 72.8 0.3 1.0 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 ETZ07234.1 - 1.6e-10 40.4 0.0 7.7e-07 28.7 0.0 2.2 2 0 0 2 2 2 2 Homeodomain-like domain HTH_28 PF13518.6 ETZ07234.1 - 4.2e-10 39.6 0.2 4.3e-05 23.6 0.0 2.1 2 0 0 2 2 2 2 Helix-turn-helix domain CENP-B_N PF04218.13 ETZ07234.1 - 1.5e-05 24.5 0.1 0.069 12.8 0.0 2.2 2 0 0 2 2 2 2 CENP-B N-terminal DNA-binding domain HTH_29 PF13551.6 ETZ07234.1 - 5.1e-05 23.2 0.0 0.0023 17.9 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn helix Sigma70_r4_2 PF08281.12 ETZ07234.1 - 0.00032 20.3 0.0 0.24 11.1 0.0 2.2 2 0 0 2 2 2 2 Sigma-70, region 4 FaeA PF04703.12 ETZ07234.1 - 0.00035 20.9 0.0 0.00083 19.7 0.0 1.6 2 0 0 2 2 2 1 FaeA-like protein HTH_17 PF12728.7 ETZ07234.1 - 0.0004 20.5 0.1 0.53 10.5 0.0 2.6 2 1 0 2 2 2 2 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 ETZ07234.1 - 0.0014 18.9 0.1 0.64 10.4 0.0 2.1 1 1 1 2 2 2 2 Transposase HTH_Tnp_ISL3 PF13542.6 ETZ07234.1 - 0.0018 17.7 0.0 0.13 11.7 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_33 PF13592.6 ETZ07234.1 - 0.0035 17.0 0.1 0.0078 15.8 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_psq PF05225.16 ETZ07234.1 - 0.0044 16.7 0.0 0.18 11.6 0.0 2.4 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_10 PF04967.12 ETZ07234.1 - 0.0065 16.2 0.0 0.036 13.9 0.0 1.9 2 0 0 2 2 2 1 HTH DNA binding domain DUF746 PF05344.11 ETZ07234.1 - 0.0075 16.1 0.0 0.043 13.7 0.0 2.2 2 1 0 2 2 2 1 Domain of Unknown Function (DUF746) LZ_Tnp_IS481 PF13011.6 ETZ07234.1 - 0.0099 16.4 0.1 0.99 10.0 0.0 2.2 2 0 0 2 2 2 1 leucine-zipper of insertion element IS481 DUF1804 PF08822.11 ETZ07234.1 - 0.014 15.4 0.0 0.81 9.6 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1804) HTH_24 PF13412.6 ETZ07234.1 - 0.014 14.9 0.0 3.1 7.4 0.0 2.4 3 0 0 3 3 2 0 Winged helix-turn-helix DNA-binding HTH_3 PF01381.22 ETZ07234.1 - 0.017 15.2 0.0 0.22 11.6 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix PAX PF00292.18 ETZ07234.1 - 0.03 14.2 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 'Paired box' domain Terminase_5 PF06056.12 ETZ07234.1 - 0.056 13.3 0.1 5 7.1 0.0 2.3 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) DUF1323 PF07037.11 ETZ07234.1 - 0.058 13.8 0.1 3.6 8.0 0.0 2.3 1 1 1 2 2 2 0 Putative transcription regulator (DUF1323) MerR_1 PF13411.6 ETZ07234.1 - 0.069 13.2 0.0 16 5.7 0.0 2.3 2 0 0 2 2 2 0 MerR HTH family regulatory protein NUMOD1 PF07453.13 ETZ07234.1 - 0.11 12.7 0.0 2.9 8.3 0.0 2.3 2 0 0 2 2 2 0 NUMOD1 domain MerR PF00376.23 ETZ07234.1 - 0.12 12.2 0.1 3.5 7.5 0.0 2.2 2 0 0 2 2 2 0 MerR family regulatory protein CcmH PF03918.14 ETZ07234.1 - 0.15 11.3 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein Sigma70_r4 PF04545.16 ETZ07234.1 - 0.16 11.5 0.0 11 5.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 MarR_2 PF12802.7 ETZ07234.1 - 0.18 11.7 0.0 1.1 9.2 0.0 1.9 2 0 0 2 2 2 0 MarR family tRNA-synt_1c PF00749.21 ETZ07235.1 - 1.5e-86 290.2 0.0 1.8e-86 289.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain CtsR_C PF17727.1 ETZ07239.1 - 0.2 11.8 2.5 5.1 7.3 0.0 3.6 4 0 0 4 4 4 0 CtsR C-terminal dimerization domain DDE_Tnp_1 PF01609.21 ETZ07240.1 - 8.4e-13 48.5 3.0 7.4e-11 42.1 3.0 2.0 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 ETZ07240.1 - 1e-11 45.0 0.2 1.3e-11 44.8 0.2 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 ETZ07240.1 - 1.4e-07 31.6 0.0 1.8e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 ETZ07240.1 - 1.9e-05 24.4 0.0 2.2e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Radical_SAM PF04055.21 ETZ07241.1 - 1.5e-23 84.0 0.0 2.8e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 ETZ07241.1 - 3.5e-13 49.4 0.3 9.8e-13 48.0 0.3 1.8 1 1 0 1 1 1 1 Uncharacterized protein family UPF0004 Fer4_12 PF13353.6 ETZ07241.1 - 0.1 12.9 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 4Fe-4S single cluster domain DDE_Tnp_IS1 PF03400.13 ETZ07242.1 - 0.00087 19.6 0.1 0.00094 19.5 0.1 1.0 1 0 0 1 1 1 1 IS1 transposase DDE_Tnp_IS240 PF13610.6 ETZ07242.1 - 0.0054 17.0 0.2 0.0064 16.7 0.2 1.1 1 0 0 1 1 1 1 DDE domain DUF4754 PF15946.5 ETZ07242.1 - 0.064 13.5 0.1 0.074 13.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4754) YqhG PF11079.8 ETZ07242.1 - 0.088 11.8 0.0 0.092 11.7 0.0 1.0 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function DDE_Tnp_IS1 PF03400.13 ETZ07243.1 - 0.00075 19.8 0.1 0.00082 19.7 0.1 1.1 1 0 0 1 1 1 1 IS1 transposase ABC_membrane PF00664.23 ETZ07244.1 - 3.6e-42 144.9 9.9 5.2e-42 144.4 9.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 ETZ07244.1 - 1.8e-32 112.7 0.0 4e-32 111.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ETZ07244.1 - 7e-08 32.2 0.0 3.6e-07 29.8 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ETZ07244.1 - 0.00015 22.2 0.0 0.00036 20.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ETZ07244.1 - 0.00018 21.8 0.1 0.001 19.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ETZ07244.1 - 0.00063 19.7 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 ETZ07244.1 - 0.00075 19.9 0.6 0.025 15.0 0.6 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 ETZ07244.1 - 0.004 16.9 0.0 0.0066 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ETZ07244.1 - 0.012 16.2 0.0 0.025 15.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 ETZ07244.1 - 0.023 14.7 0.1 0.48 10.4 0.1 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 ETZ07244.1 - 0.043 13.0 0.0 0.13 11.5 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain DUF3584 PF12128.8 ETZ07244.1 - 0.089 10.3 0.0 0.16 9.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_29 PF13555.6 ETZ07244.1 - 0.11 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 ETZ07244.1 - 0.13 12.0 0.1 0.42 10.3 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein SbcCD_C PF13558.6 ETZ07244.1 - 0.16 12.2 0.2 2.2 8.6 0.2 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 ETZ07244.1 - 0.17 11.4 0.0 0.48 10.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 ETZ07244.1 - 0.21 11.3 0.0 0.39 10.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain DDE_Tnp_ISAZ013 PF07592.11 ETZ07245.1 - 0.00019 20.5 0.0 0.00027 20.1 0.0 1.2 1 0 0 1 1 1 1 Rhodopirellula transposase DDE domain DDE_Tnp_ISAZ013 PF07592.11 ETZ07246.1 - 2.4e-18 66.2 0.8 2.5e-18 66.1 0.8 1.0 1 0 0 1 1 1 1 Rhodopirellula transposase DDE domain DDE_Tnp_IS1 PF03400.13 ETZ07247.1 - 0.0099 16.2 0.1 0.012 16.0 0.1 1.2 1 0 0 1 1 1 1 IS1 transposase PufQ PF05398.11 ETZ07247.1 - 0.058 13.5 0.0 0.11 12.7 0.0 1.5 1 1 0 1 1 1 0 PufQ cytochrome subunit DDE_Tnp_IS1 PF03400.13 ETZ07248.1 - 0.0081 16.5 0.1 0.0097 16.2 0.1 1.1 1 0 0 1 1 1 1 IS1 transposase Trans_reg_C PF00486.28 ETZ07249.1 - 1.3e-11 44.4 0.8 3.1e-11 43.2 0.8 1.6 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Bac_DNA_binding PF00216.21 ETZ07250.1 - 5.4e-26 90.6 0.0 6.4e-26 90.4 0.0 1.1 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 ETZ07250.1 - 1.4e-10 41.3 0.0 2e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_euk_1 PF14908.6 ETZ07250.1 - 1.9e-05 24.7 0.0 2.5e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 HU-CCDC81_bac_2 PF18175.1 ETZ07250.1 - 0.00051 19.9 0.0 0.00094 19.0 0.0 1.4 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 HU-DNA_bdg PF14848.6 ETZ07250.1 - 0.00089 19.3 0.0 0.012 15.6 0.0 1.9 2 0 0 2 2 2 1 DNA-binding domain HU-CCDC81_euk_2 PF18289.1 ETZ07250.1 - 0.082 13.1 0.1 0.13 12.5 0.1 1.2 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 TFIIA_gamma_N PF02268.16 ETZ07250.1 - 0.16 12.0 0.0 0.31 11.1 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IIA, gamma subunit, helical domain OmpA_membrane PF01389.17 ETZ07251.1 - 0.12 12.1 0.1 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 OmpA-like transmembrane domain PagL PF09411.10 ETZ07251.1 - 0.17 12.1 2.4 0.79 9.9 0.1 2.8 3 1 0 3 3 3 0 Lipid A 3-O-deacylase (PagL) Radical_SAM PF04055.21 ETZ07252.1 - 9.3e-30 104.2 0.0 2.3e-29 102.9 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 ETZ07252.1 - 4.9e-26 90.6 0.2 1.1e-25 89.6 0.2 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 ETZ07252.1 - 6.6e-07 29.2 0.0 1.6e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 TRAM domain Fer4_12 PF13353.6 ETZ07252.1 - 0.041 14.2 0.3 2.4 8.4 0.0 2.9 3 0 0 3 3 3 0 4Fe-4S single cluster domain SecD_SecF PF02355.16 ETZ07252.1 - 0.15 11.4 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein export membrane protein Cas9-BH PF16593.5 ETZ07252.1 - 0.18 11.6 1.6 0.47 10.2 1.6 1.7 1 0 0 1 1 1 0 Bridge helix of CRISPR-associated endonuclease Cas9 DUF5082 PF16888.5 ETZ07252.1 - 0.19 12.0 0.9 3.7 7.8 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Acyltransferase PF01553.21 ETZ07253.1 - 3.8e-15 55.7 0.1 6e-15 55.1 0.1 1.4 1 0 0 1 1 1 1 Acyltransferase ParBc PF02195.18 ETZ07254.1 - 3.6e-11 43.2 0.0 1.4e-10 41.4 0.0 1.9 2 0 0 2 2 2 1 ParB-like nuclease domain Sigma70_ECF PF07638.11 ETZ07258.1 - 0.00012 22.0 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 ECF sigma factor Sigma70_r2 PF04542.14 ETZ07258.1 - 0.00012 21.7 0.0 0.0002 21.1 0.0 1.3 1 0 0 1 1 1 1 Sigma-70 region 2 TrmB PF01978.19 ETZ07258.1 - 0.12 12.2 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Phage_Mu_Gam PF07352.12 ETZ07259.1 - 0.0043 17.0 0.5 0.0051 16.7 0.5 1.1 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein Phage_term_sma PF07141.11 ETZ07259.1 - 0.028 14.2 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative bacteriophage terminase small subunit AAA_24 PF13479.6 ETZ07260.1 - 6.1e-40 137.1 0.0 7.3e-40 136.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain Hom_end_hint PF05203.16 ETZ07262.1 - 8.2e-09 35.7 0.0 8.7e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Hom_end-associated Hint YqaJ PF09588.10 ETZ07266.1 - 5.5e-05 23.3 0.0 9.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain PDDEXK_1 PF12705.7 ETZ07266.1 - 0.00017 21.6 0.1 0.00021 21.3 0.1 1.2 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily AAA_25 PF13481.6 ETZ07267.1 - 4e-21 75.5 0.0 1.9e-20 73.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain Toprim_4 PF13662.6 ETZ07267.1 - 0.0016 18.9 0.0 0.0055 17.1 0.0 1.9 2 0 0 2 2 2 1 Toprim domain Toprim_2 PF13155.6 ETZ07267.1 - 0.0033 17.8 0.0 0.0085 16.5 0.0 1.7 1 0 0 1 1 1 1 Toprim-like Toprim PF01751.22 ETZ07267.1 - 0.072 13.3 0.0 0.21 11.9 0.0 1.8 1 0 0 1 1 1 0 Toprim domain DnaB_C PF03796.15 ETZ07267.1 - 0.076 12.3 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Rhodanese_C PF12368.8 ETZ07268.1 - 0.053 13.9 0.4 0.089 13.2 0.4 1.3 1 0 0 1 1 1 0 Rhodanase C-terminal Pyr_redox_dim PF02852.22 ETZ07268.1 - 0.15 12.4 0.0 0.61 10.4 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain LexA_DNA_bind PF01726.16 ETZ07270.1 - 7.2e-12 44.9 0.1 1.1e-11 44.3 0.1 1.3 1 0 0 1 1 1 1 LexA DNA binding domain Peptidase_S24 PF00717.23 ETZ07270.1 - 1e-09 38.2 0.1 1.8e-09 37.4 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like MarR_2 PF12802.7 ETZ07270.1 - 0.00011 22.0 0.2 0.00017 21.4 0.2 1.3 1 0 0 1 1 1 1 MarR family GntR PF00392.21 ETZ07270.1 - 0.00037 20.1 0.2 0.00066 19.3 0.2 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Fe_dep_repress PF01325.19 ETZ07270.1 - 0.00073 19.7 0.0 0.0012 19.0 0.0 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_Crp_2 PF13545.6 ETZ07270.1 - 0.0035 17.3 0.0 0.0069 16.3 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Rrf2 PF02082.20 ETZ07270.1 - 0.0086 16.4 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator TrmB PF01978.19 ETZ07270.1 - 0.024 14.5 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB MarR PF01047.22 ETZ07270.1 - 0.029 14.3 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_IclR PF09339.10 ETZ07270.1 - 0.03 14.1 0.4 0.078 12.8 0.0 1.8 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_DeoR PF08220.12 ETZ07270.1 - 0.072 12.9 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain DUF2924 PF11149.8 ETZ07272.1 - 4.9e-46 156.5 0.0 5.6e-46 156.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2924) RAMA PF18755.1 ETZ07272.1 - 0.00028 21.3 0.0 0.00042 20.7 0.0 1.4 1 0 0 1 1 1 1 Restriction Enzyme Adenine Methylase Associated Resolvase PF00239.21 ETZ07273.1 - 5.3e-35 120.7 0.0 1e-34 119.8 0.0 1.5 1 0 0 1 1 1 1 Resolvase, N terminal domain Recombinase PF07508.13 ETZ07273.1 - 2.2e-12 47.3 0.0 8e-12 45.5 0.0 2.0 1 0 0 1 1 1 1 Recombinase Zn_ribbon_recom PF13408.6 ETZ07273.1 - 3.5e-12 46.6 2.8 9.4e-12 45.3 2.8 1.8 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain Hydrolase_4 PF12146.8 ETZ07275.1 - 0.00012 21.4 0.0 0.00024 20.4 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ETZ07275.1 - 0.0011 18.7 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 ETZ07275.1 - 0.0065 15.4 0.0 0.012 14.5 0.0 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 ETZ07275.1 - 0.021 14.6 0.0 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF2974 PF11187.8 ETZ07275.1 - 0.035 13.7 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Peptidase_S9 PF00326.21 ETZ07275.1 - 0.12 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Esterase PF00756.20 ETZ07275.1 - 0.17 11.5 0.0 8.7 5.9 0.0 2.1 2 0 0 2 2 2 0 Putative esterase Asp_Glu_race PF01177.22 ETZ07279.1 - 1e-44 153.0 0.1 1.2e-44 152.8 0.1 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Ala_racemase_N PF01168.20 ETZ07280.1 - 5.9e-59 199.4 0.0 7.1e-59 199.1 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Ala_racemase_C PF00842.21 ETZ07280.1 - 1.5e-29 102.3 0.2 5.5e-29 100.5 0.2 1.8 2 0 0 2 2 2 1 Alanine racemase, C-terminal domain Acetyltransf_1 PF00583.25 ETZ07281.1 - 2.1e-12 47.3 0.0 2.5e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ETZ07281.1 - 2.2e-10 40.6 0.0 3e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ETZ07281.1 - 4.2e-09 36.7 0.0 5.7e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ETZ07281.1 - 4.1e-05 23.6 0.0 5.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 ETZ07281.1 - 0.0087 16.2 0.0 0.0099 16.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ETZ07281.1 - 0.031 14.3 0.0 0.036 14.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 ETZ07281.1 - 0.1 12.6 0.0 0.2 11.6 0.0 1.6 1 1 0 1 1 1 0 FR47-like protein Rapsyn_N PF10579.9 ETZ07281.1 - 0.17 12.0 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region Acetyltransf_10 PF13673.7 ETZ07282.1 - 7.9e-08 32.3 0.0 1.2e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ETZ07282.1 - 3.6e-07 30.5 0.0 6.2e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETZ07282.1 - 7e-06 26.3 0.0 1.2e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family AAA_18 PF13238.6 ETZ07282.1 - 3.5e-05 24.4 0.0 0.0001 22.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 ETZ07282.1 - 0.0027 17.0 0.1 0.01 15.1 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin Acetyltransf_4 PF13420.7 ETZ07282.1 - 0.037 14.2 0.1 0.19 11.9 0.0 2.1 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain PRK PF00485.18 ETZ07282.1 - 0.07 12.9 0.0 0.8 9.4 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 ETZ07282.1 - 0.19 12.1 0.1 0.46 10.8 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain Acetyltransf_3 PF13302.7 ETZ07283.1 - 3.3e-31 108.8 0.0 3.8e-31 108.6 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETZ07283.1 - 4.4e-09 36.6 0.0 5.3e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 ETZ07283.1 - 2.2e-05 24.3 0.0 4.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 ETZ07283.1 - 7.1e-05 23.0 0.0 8.9e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 ETZ07283.1 - 0.018 14.7 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase Peptidase_S66C PF17676.1 ETZ07284.1 - 7.8e-31 107.2 0.0 1.7e-30 106.1 0.0 1.5 2 0 0 2 2 2 1 LD-carboxypeptidase C-terminal domain Peptidase_S66 PF02016.15 ETZ07284.1 - 1.7e-30 105.6 0.0 3.4e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 LD-carboxypeptidase N-terminal domain Thioredoxin_4 PF13462.6 ETZ07285.1 - 0.00016 21.8 1.0 0.0002 21.6 0.3 1.5 2 0 0 2 2 2 1 Thioredoxin Thioredoxin PF00085.20 ETZ07285.1 - 0.00078 19.4 0.3 0.0021 18.0 0.2 1.6 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 ETZ07285.1 - 0.062 13.6 0.7 0.42 11.0 0.1 2.2 2 1 0 2 2 2 0 Thioredoxin-like tRNA-synt_2b PF00587.25 ETZ07287.1 - 1.3e-28 100.1 0.0 3.2e-28 98.9 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 ETZ07287.1 - 1.1e-20 73.9 0.5 1.8e-20 73.2 0.5 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain CENP-K PF11802.8 ETZ07287.1 - 0.014 14.9 0.9 0.023 14.3 0.9 1.2 1 0 0 1 1 1 0 Centromere-associated protein K DUF4201 PF13870.6 ETZ07287.1 - 0.062 13.0 1.8 0.13 12.0 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Peptidase_M23 PF01551.22 ETZ07288.1 - 2e-11 44.0 0.0 4e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M23 LysM PF01476.20 ETZ07288.1 - 4.5e-09 36.2 0.2 2.2e-08 34.0 0.0 2.1 2 0 0 2 2 2 1 LysM domain EamA PF00892.20 ETZ07289.1 - 4.7e-23 81.9 41.4 8.6e-15 55.1 13.3 2.1 2 0 0 2 2 2 2 EamA-like transporter family HTH_Tnp_IS630 PF01710.16 ETZ07290.1 - 0.021 14.8 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE_3 PF13358.6 ETZ07291.1 - 2.8e-06 27.1 0.0 2.8e-06 27.1 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Methyltransf_25 PF13649.6 ETZ07292.1 - 2.3e-08 34.6 0.0 7.1e-08 33.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETZ07292.1 - 3.7e-07 30.0 0.0 6.2e-07 29.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETZ07292.1 - 1.2e-06 29.1 0.0 2.7e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ETZ07292.1 - 0.00016 21.2 0.0 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 ETZ07292.1 - 0.0045 17.7 0.0 0.012 16.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 ETZ07292.1 - 0.0068 15.7 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain RrnaAD PF00398.20 ETZ07292.1 - 0.0077 15.3 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.6 ETZ07292.1 - 0.011 15.6 0.0 0.017 14.9 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_5 PF01795.19 ETZ07292.1 - 0.029 13.9 0.0 1.8 8.0 0.0 2.1 2 0 0 2 2 2 0 MraW methylase family Methyltransf_18 PF12847.7 ETZ07292.1 - 0.058 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain AAA_26 PF13500.6 ETZ07293.1 - 1.7e-47 161.8 0.2 2.1e-47 161.5 0.2 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 ETZ07293.1 - 0.053 13.6 1.7 0.32 11.1 1.7 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DDE_3 PF13358.6 ETZ07294.1 - 1.1e-21 77.1 0.7 1.3e-21 76.9 0.7 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.26 ETZ07294.1 - 0.0048 17.1 0.0 0.0053 16.9 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS1595 PF12762.7 ETZ07294.1 - 0.085 12.9 0.0 0.094 12.7 0.0 1.2 1 0 0 1 1 1 0 ISXO2-like transposase domain EF-hand_1 PF00036.32 ETZ07296.1 - 0.18 11.4 2.4 11 5.8 0.3 3.8 3 0 0 3 3 3 0 EF hand EF-hand_11 PF08976.11 ETZ07296.1 - 0.68 10.8 4.2 1.9 9.4 1.3 3.3 2 1 0 2 2 2 0 EF-hand domain YqbF PF14553.6 ETZ07296.1 - 8 6.4 7.5 4 7.4 1.9 3.4 3 0 0 3 3 3 0 YqbF, hypothetical protein domain RrnaAD PF00398.20 ETZ07298.1 - 1.5e-39 135.7 0.0 1.7e-39 135.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase SRP54 PF00448.22 ETZ07299.1 - 2.4e-53 180.7 0.2 2.2e-52 177.6 0.2 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 ETZ07299.1 - 0.00043 20.0 0.0 0.00072 19.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 ETZ07299.1 - 0.001 18.4 0.0 0.0035 16.6 0.0 1.9 1 1 0 1 1 1 1 Zeta toxin SRP54_N PF02881.19 ETZ07299.1 - 0.0014 18.8 0.0 0.0031 17.7 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_22 PF13401.6 ETZ07299.1 - 0.0018 18.6 0.0 0.0048 17.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 ETZ07299.1 - 0.0022 17.6 0.1 0.019 14.6 0.1 2.3 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 ETZ07299.1 - 0.0027 18.2 0.0 0.0084 16.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ETZ07299.1 - 0.0057 17.1 0.1 0.0097 16.3 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 ETZ07299.1 - 0.0057 16.0 0.0 0.0094 15.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 ETZ07299.1 - 0.0059 16.5 1.2 0.022 14.7 0.2 2.3 3 0 0 3 3 3 1 NACHT domain Arf PF00025.21 ETZ07299.1 - 0.016 14.6 0.0 0.055 12.9 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family Rad17 PF03215.15 ETZ07299.1 - 0.022 14.7 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA PF00004.29 ETZ07299.1 - 0.027 14.9 0.0 0.061 13.7 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 ETZ07299.1 - 0.029 14.4 0.0 0.13 12.3 0.0 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.27 ETZ07299.1 - 0.043 14.3 0.0 0.067 13.7 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 ETZ07299.1 - 0.067 13.3 0.2 0.12 12.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 ETZ07299.1 - 0.083 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase SRPRB PF09439.10 ETZ07299.1 - 0.083 12.3 0.1 5.3 6.4 0.0 2.5 1 1 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.6 ETZ07299.1 - 0.1 12.9 0.2 0.31 11.3 0.1 1.9 1 1 1 2 2 2 0 AAA domain Roc PF08477.13 ETZ07299.1 - 0.12 12.6 0.4 0.43 10.8 0.2 2.0 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_26 PF13500.6 ETZ07299.1 - 0.13 12.1 0.1 1.3 8.8 0.1 2.2 1 1 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 ETZ07299.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Helicase SecB PF02556.14 ETZ07301.1 - 1.4e-24 86.6 0.0 1.6e-24 86.4 0.0 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit SecB UvrD-helicase PF00580.21 ETZ07302.1 - 5.4e-65 220.0 2.6 5.4e-65 220.0 2.6 3.3 2 2 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 ETZ07302.1 - 2.8e-59 201.2 0.7 1.7e-58 198.7 0.2 2.3 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 ETZ07302.1 - 1.4e-31 109.8 0.0 3.6e-31 108.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 ETZ07302.1 - 5.8e-09 35.6 0.3 2.1e-08 33.8 0.3 2.0 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 ETZ07302.1 - 9.5e-07 28.8 0.1 0.0011 18.7 0.0 3.5 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 ETZ07302.1 - 1.2e-05 25.1 0.0 0.00034 20.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.6 ETZ07302.1 - 0.01 15.5 0.7 4.7 6.8 0.0 3.1 2 1 1 3 3 3 0 AAA domain T2SSE PF00437.20 ETZ07302.1 - 0.06 12.4 0.0 0.16 11.0 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein DEAD PF00270.29 ETZ07302.1 - 0.13 12.1 0.1 0.33 10.7 0.1 1.8 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_11 PF13086.6 ETZ07302.1 - 0.19 11.5 1.4 0.55 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain DDE_3 PF13358.6 ETZ07303.1 - 5.4e-11 42.5 0.1 6.1e-11 42.3 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease RMMBL PF07521.12 ETZ07304.1 - 1.4e-11 44.2 0.3 1.2e-07 31.5 0.1 3.2 3 0 0 3 3 3 2 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 ETZ07304.1 - 7e-11 42.0 0.2 1.3e-10 41.1 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ETZ07304.1 - 3.8e-09 36.8 2.0 6.9e-09 36.0 2.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 ETZ07304.1 - 0.0099 15.3 0.0 0.029 13.8 0.0 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain RNase_J_C PF17770.1 ETZ07304.1 - 0.15 13.1 0.0 0.31 12.1 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease J C-terminal domain Podoplanin PF05808.11 ETZ07306.1 - 0.026 14.6 0.9 0.026 14.6 0.9 1.5 1 1 0 2 2 2 0 Podoplanin DUF4901 PF16244.5 ETZ07306.1 - 0.031 13.6 1.0 0.045 13.1 0.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4901) C_LFY_FLO PF17538.2 ETZ07306.1 - 0.041 13.4 0.0 0.056 12.9 0.0 1.2 1 0 0 1 1 1 0 DNA Binding Domain (C-terminal) Leafy/Floricaula Colicin PF01024.19 ETZ07306.1 - 0.051 13.5 0.2 0.078 12.9 0.2 1.3 1 0 0 1 1 1 0 Colicin pore forming domain Exonuc_VII_L PF02601.15 ETZ07309.1 - 7.6e-79 265.4 0.0 1.1e-78 264.9 0.0 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit tRNA_anti_2 PF13742.6 ETZ07309.1 - 1.8e-24 85.8 0.5 4.8e-24 84.4 0.1 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA_anti-codon PF01336.25 ETZ07309.1 - 7.2e-05 22.7 0.0 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DHQ_synthase PF01761.20 ETZ07309.1 - 0.00024 20.3 0.0 0.00046 19.4 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase HbrB PF08539.11 ETZ07309.1 - 0.083 12.9 0.6 0.14 12.2 0.6 1.3 1 0 0 1 1 1 0 HbrB-like ABC_tran PF00005.27 ETZ07311.1 - 5.5e-30 104.7 0.0 7.5e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ETZ07311.1 - 2.4e-05 24.3 1.1 0.035 13.9 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ETZ07311.1 - 7.3e-05 22.3 0.2 0.00017 21.1 0.2 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ETZ07311.1 - 0.0005 19.8 0.1 0.001 18.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ETZ07311.1 - 0.0013 18.6 0.1 0.0026 17.7 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 ETZ07311.1 - 0.0062 16.3 1.1 1.5 8.5 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 ETZ07311.1 - 0.008 16.3 0.2 0.059 13.4 0.1 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 ETZ07311.1 - 0.0086 16.6 0.0 0.011 16.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ETZ07311.1 - 0.032 14.6 0.9 0.11 12.8 0.9 1.8 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 ETZ07311.1 - 0.056 13.2 0.1 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein SbcCD_C PF13558.6 ETZ07311.1 - 0.093 13.0 0.0 1 9.6 0.0 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit dNK PF01712.19 ETZ07311.1 - 0.1 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_25 PF13481.6 ETZ07311.1 - 0.11 12.1 0.2 13 5.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 ETZ07311.1 - 0.13 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 ETZ07311.1 - 0.15 12.3 0.6 0.63 10.3 0.6 2.0 1 1 0 1 1 1 0 AAA domain GST_N_3 PF13417.6 ETZ07312.1 - 1.8e-11 44.3 0.0 3.7e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ETZ07312.1 - 2.4e-07 30.9 0.0 4.5e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ETZ07312.1 - 9.4e-07 29.1 0.0 2.1e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ETZ07312.1 - 1.5e-05 25.1 0.0 0.00026 21.1 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ETZ07312.1 - 0.0007 19.6 0.2 0.0018 18.2 0.2 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ETZ07312.1 - 0.017 15.5 0.0 0.046 14.1 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Glutaredoxin2_C PF04399.13 ETZ07312.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.4 1 1 0 1 1 1 0 Glutaredoxin 2, C terminal domain DUF4096 PF13340.6 ETZ07315.1 - 3e-05 24.1 0.0 3e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) Glucosaminidase PF01832.20 ETZ07316.1 - 1.2e-13 51.3 0.1 2.2e-13 50.5 0.1 1.4 1 0 0 1 1 1 1 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase NifU PF01106.17 ETZ07317.1 - 9.6e-23 80.1 0.0 1.4e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.11 ETZ07317.1 - 1.2e-19 70.1 0.0 2.1e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal DDE_Tnp_ISAZ013 PF07592.11 ETZ07318.1 - 1e-07 31.3 0.0 1.4e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Rhodopirellula transposase DDE domain Hydrolase_4 PF12146.8 ETZ07319.1 - 7.9e-07 28.6 0.0 2.2e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ETZ07319.1 - 1.2e-06 28.3 0.0 5.4e-06 26.2 0.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 ETZ07319.1 - 0.00017 21.3 0.0 0.00029 20.5 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 ETZ07319.1 - 0.00028 20.4 0.0 0.39 10.2 0.0 2.1 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 ETZ07319.1 - 0.0006 20.5 0.0 0.0024 18.5 0.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF818 PF05677.12 ETZ07319.1 - 0.0065 15.5 0.0 0.0089 15.0 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Lig_C PF18330.1 ETZ07320.1 - 0.025 14.6 0.1 0.035 14.1 0.1 1.1 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region Urm1 PF09138.11 ETZ07320.1 - 0.075 13.4 0.1 0.09 13.1 0.1 1.2 1 0 0 1 1 1 0 Urm1 (Ubiquitin related modifier) Exonuc_VII_S PF02609.16 ETZ07322.1 - 2.7e-19 69.0 1.3 3.7e-19 68.5 1.3 1.2 1 0 0 1 1 1 1 Exonuclease VII small subunit Thioredoxin_7 PF13899.6 ETZ07323.1 - 2.1e-08 34.2 0.0 4.1e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like DsbC PF11412.8 ETZ07323.1 - 2.5e-06 27.6 0.0 4.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Disulphide bond corrector protein DsbC Thioredox_DsbH PF03190.15 ETZ07323.1 - 0.0012 18.9 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 zf-C4 PF00105.18 ETZ07324.1 - 0.045 14.2 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) Glyco_transf_43 PF03360.16 ETZ07324.1 - 0.061 13.2 0.1 8.5 6.2 0.1 2.5 2 0 0 2 2 2 0 Glycosyltransferase family 43 SAM_Exu PF18609.1 ETZ07324.1 - 0.087 12.9 0.0 0.74 10.0 0.0 2.8 1 0 0 1 1 1 0 Exuperantia SAM-like domain DUF383 PF04063.14 ETZ07324.1 - 0.15 11.8 6.4 7.4 6.2 0.0 4.6 4 1 1 5 5 5 0 Domain of unknown function (DUF383) APG5 PF04106.12 ETZ07324.1 - 2.1 7.9 5.7 0.71 9.4 1.2 2.1 2 1 0 2 2 2 0 Autophagy protein Apg5 Aminotran_3 PF00202.21 ETZ07326.1 - 9.1e-109 363.8 0.0 1e-108 363.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Metallophos_2 PF12850.7 ETZ07326.1 - 0.025 14.8 0.0 0.075 13.2 0.0 1.7 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain DDE_Tnp_1_3 PF13612.6 ETZ07328.1 - 1.2e-07 31.9 0.1 1.5e-07 31.5 0.1 1.1 1 0 0 1 1 1 1 Transposase DDE domain Stork_head PF10264.9 ETZ07328.1 - 0.0024 18.0 0.0 0.0037 17.4 0.0 1.3 1 0 0 1 1 1 1 Winged helix Storkhead-box1 domain CBS PF00571.28 ETZ07329.1 - 1.1e-12 48.2 0.4 1.7e-05 25.2 0.1 2.5 2 0 0 2 2 2 2 CBS domain SIS PF01380.22 ETZ07329.1 - 4.4e-12 46.0 0.0 6.7e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 SIS domain Syntaxin_2 PF14523.6 ETZ07331.1 - 0.026 14.9 0.1 0.026 14.9 0.1 1.0 1 0 0 1 1 1 0 Syntaxin-like protein DDE_Tnp_1 PF01609.21 ETZ07332.1 - 3e-10 40.1 2.4 6.3e-08 32.5 2.4 2.3 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 ETZ07332.1 - 3.8e-09 36.8 0.1 5.4e-09 36.3 0.1 1.2 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 ETZ07332.1 - 0.00025 21.1 0.0 0.00035 20.6 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain CTP_transf_3 PF02348.19 ETZ07334.1 - 6.8e-24 85.0 0.0 9.5e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 ETZ07334.1 - 2.7e-05 24.6 0.0 5.1e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 MobA-like NTP transferase domain DDE_Tnp_1_assoc PF13808.6 ETZ07335.1 - 3.8e-25 87.7 0.0 1.1e-24 86.3 0.0 1.7 2 1 0 2 2 2 1 DDE_Tnp_1-associated DDE_Tnp_1 PF01609.21 ETZ07335.1 - 0.092 12.4 0.0 0.2 11.3 0.0 1.6 2 0 0 2 2 2 0 Transposase DDE domain PRD_Mga PF08270.11 ETZ07335.1 - 0.096 12.3 0.0 0.36 10.5 0.0 1.9 1 1 1 2 2 2 0 M protein trans-acting positive regulator (MGA) PRD domain DDE_Tnp_1 PF01609.21 ETZ07336.1 - 6.9e-07 29.1 0.3 8.6e-07 28.8 0.3 1.2 1 0 0 1 1 1 1 Transposase DDE domain THOC2_N PF16134.5 ETZ07337.1 - 0.0057 15.4 0.8 0.0065 15.2 0.8 1.2 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus EF-G-binding_N PF07299.11 ETZ07337.1 - 0.45 11.1 5.9 2.4 8.7 3.9 2.5 2 1 0 2 2 2 0 Elongation factor G-binding protein, N-terminal Fic_N PF13784.6 ETZ07340.1 - 6.3e-26 90.2 0.0 1.3e-25 89.2 0.0 1.6 1 0 0 1 1 1 1 Fic/DOC family N-terminal Fic PF02661.18 ETZ07340.1 - 9e-23 81.0 0.0 2.1e-22 79.8 0.0 1.7 1 0 0 1 1 1 1 Fic/DOC family HTH_DeoR PF08220.12 ETZ07340.1 - 0.00033 20.4 0.0 0.00086 19.0 0.0 1.6 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain TrmB PF01978.19 ETZ07340.1 - 0.0026 17.6 0.0 0.0061 16.4 0.0 1.7 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.12 ETZ07340.1 - 0.0042 17.0 1.4 0.025 14.5 0.1 2.8 3 0 0 3 3 3 1 HTH domain Ribosomal_S25 PF03297.15 ETZ07340.1 - 0.011 15.9 0.2 0.02 15.1 0.2 1.4 1 0 0 1 1 1 0 S25 ribosomal protein HTH_AsnC-type PF13404.6 ETZ07340.1 - 0.015 15.1 0.1 0.16 11.8 0.0 2.3 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Rrf2 PF02082.20 ETZ07340.1 - 0.03 14.7 0.1 0.098 13.0 0.1 1.8 2 0 0 2 2 2 0 Transcriptional regulator MarR_2 PF12802.7 ETZ07340.1 - 0.034 14.0 0.0 0.081 12.8 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.6 ETZ07340.1 - 0.04 13.5 0.1 0.11 12.0 0.1 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Fe_dep_repress PF01325.19 ETZ07340.1 - 0.048 13.9 0.1 0.16 12.2 0.0 2.0 2 0 0 2 2 1 0 Iron dependent repressor, N-terminal DNA binding domain FtsK_gamma PF09397.10 ETZ07340.1 - 0.052 13.4 0.2 0.18 11.6 0.1 2.0 1 1 1 2 2 2 0 Ftsk gamma domain MarR PF01047.22 ETZ07340.1 - 0.053 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 MarR family DUF5635 PF18685.1 ETZ07340.1 - 0.096 12.6 0.1 4.4 7.3 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5635) PBECR3 PF18812.1 ETZ07340.1 - 0.096 12.6 0.3 5.5 7.0 0.2 2.2 2 0 0 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 Acetyltransf_3 PF13302.7 ETZ07341.1 - 3.6e-07 30.9 0.0 3.6e-07 30.9 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ETZ07342.1 - 8.5e-20 71.8 0.1 1e-19 71.6 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETZ07342.1 - 1.7e-05 25.0 0.0 2e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 ETZ07342.1 - 0.066 12.9 0.0 0.087 12.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain APH_6_hur PF04655.14 ETZ07343.1 - 7.4e-37 127.1 0.0 9.5e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Aminoglycoside/hydroxyurea antibiotic resistance kinase APH PF01636.23 ETZ07343.1 - 1.9e-07 31.3 0.1 2.9e-07 30.6 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 ETZ07343.1 - 0.0086 15.3 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Fructosamine kinase DUF2975 PF11188.8 ETZ07344.1 - 1.6e-13 50.7 6.0 4.4e-13 49.3 6.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2975) DUF3098 PF11297.8 ETZ07344.1 - 0.0066 16.0 0.1 1.1 8.9 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF3098) LIDHydrolase PF10230.9 ETZ07344.1 - 0.031 13.8 0.1 0.048 13.2 0.1 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF4668 PF15701.5 ETZ07344.1 - 1.3 8.9 9.1 3.5 7.4 0.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4668) HTH_26 PF13443.6 ETZ07345.1 - 2.3e-20 72.8 0.6 2.5e-20 72.7 0.6 1.0 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_3 PF01381.22 ETZ07345.1 - 3.2e-05 23.9 0.0 3.7e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 ETZ07345.1 - 0.00016 21.7 0.0 0.00016 21.7 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 ETZ07345.1 - 0.0027 18.0 0.0 0.0029 17.9 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 ETZ07345.1 - 0.065 13.2 0.2 0.076 13.0 0.2 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain MAD PF05557.13 ETZ07345.1 - 0.11 10.8 0.0 0.11 10.8 0.0 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein Hydrolase_4 PF12146.8 ETZ07346.1 - 1.4e-07 31.1 0.0 2.1e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 ETZ07346.1 - 0.00055 19.5 0.1 0.015 14.8 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 ETZ07346.1 - 0.0017 18.2 0.0 0.0064 16.4 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.11 ETZ07346.1 - 0.0062 16.5 0.0 0.03 14.3 0.0 1.9 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 ETZ07346.1 - 0.072 12.7 0.1 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase (FSH1) GyrI-like PF06445.15 ETZ07347.1 - 2.5e-30 105.8 0.0 3.5e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 GyrI-like small molecule binding domain HTH_18 PF12833.7 ETZ07347.1 - 1.2e-23 83.2 0.1 1.9e-23 82.5 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 ETZ07347.1 - 8.7e-17 60.8 0.1 2.3e-09 37.1 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Cass2 PF14526.6 ETZ07347.1 - 6.7e-13 49.0 0.0 1.4e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Integron-associated effector binding protein TspO_MBR PF03073.15 ETZ07348.1 - 7.4e-26 90.8 19.7 2.2e-14 53.7 11.7 2.0 1 1 1 2 2 2 2 TspO/MBR family LapA_dom PF06305.11 ETZ07348.1 - 0.25 11.2 0.2 0.25 11.2 0.2 2.8 3 1 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Acetyltransf_10 PF13673.7 ETZ07350.1 - 9.3e-14 51.5 0.0 1.2e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETZ07350.1 - 1.1e-08 35.3 0.0 1.3e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ETZ07350.1 - 2e-08 34.6 0.0 2.6e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ETZ07350.1 - 0.0043 17.1 0.0 0.0066 16.6 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase PanZ PF12568.8 ETZ07350.1 - 0.036 13.8 0.0 0.04 13.6 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Methyltransf_25 PF13649.6 ETZ07351.1 - 5.8e-10 39.8 0.0 1e-09 39.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETZ07351.1 - 3.3e-08 34.2 0.0 5.1e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETZ07351.1 - 3.2e-07 30.4 0.0 5.8e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETZ07351.1 - 3.8e-07 30.0 0.0 5e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETZ07351.1 - 4.2e-05 24.1 0.0 7.2e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 ETZ07351.1 - 0.00062 19.2 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB N2227 PF07942.12 ETZ07351.1 - 0.025 13.8 0.0 0.15 11.3 0.0 1.9 2 0 0 2 2 2 0 N2227-like protein UPF0020 PF01170.18 ETZ07351.1 - 0.027 14.1 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 HAD_2 PF13419.6 ETZ07352.1 - 6.7e-07 29.6 0.1 9.4e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ETZ07352.1 - 0.00012 22.5 0.0 0.005 17.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ETZ07352.1 - 0.046 13.8 0.0 0.089 12.9 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like APH PF01636.23 ETZ07353.1 - 1.5e-33 116.7 0.1 1.9e-33 116.4 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 ETZ07353.1 - 0.00083 18.3 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 ETZ07353.1 - 0.11 12.1 0.0 0.32 10.5 0.0 1.8 1 1 0 1 1 1 0 Choline/ethanolamine kinase Acetyltransf_1 PF00583.25 ETZ07354.1 - 4.4e-12 46.3 0.0 5.3e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ETZ07354.1 - 3e-09 37.2 0.0 4.2e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ETZ07354.1 - 3e-08 33.6 0.0 3.6e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ETZ07354.1 - 0.0021 18.2 0.0 0.0031 17.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ETZ07354.1 - 0.056 13.4 0.0 0.094 12.7 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein FAM150 PF15129.6 ETZ07354.1 - 0.061 13.5 0.0 0.096 12.8 0.0 1.2 1 0 0 1 1 1 0 FAM150 family Acetyltransf_CG PF14542.6 ETZ07354.1 - 0.077 13.1 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 ETZ07355.1 - 3e-11 43.3 0.0 3.5e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ETZ07355.1 - 7.4e-11 42.3 0.0 1.1e-10 41.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETZ07355.1 - 1.8e-10 41.0 0.0 2.2e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 ETZ07355.1 - 0.0041 17.2 0.0 0.008 16.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ETZ07355.1 - 0.12 12.3 0.0 0.59 10.1 0.0 1.9 1 1 0 1 1 1 0 FR47-like protein APH PF01636.23 ETZ07356.1 - 7.5e-14 52.2 0.0 1.1e-13 51.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Acetyltransf_8 PF13523.6 ETZ07356.1 - 4.1e-12 46.0 0.0 7.6e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Choline_kinase PF01633.20 ETZ07356.1 - 8.8e-09 35.3 0.2 2.2e-08 33.9 0.2 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase Acetyltransf_3 PF13302.7 ETZ07356.1 - 1.5e-08 35.4 0.0 3.4e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETZ07356.1 - 0.00065 19.9 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family RIO1 PF01163.22 ETZ07356.1 - 0.017 14.7 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DUF1679 PF07914.11 ETZ07356.1 - 0.02 13.7 0.2 0.033 13.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) EcKinase PF02958.20 ETZ07356.1 - 0.029 13.7 0.0 0.074 12.4 0.0 1.7 1 1 0 1 1 1 0 Ecdysteroid kinase Pkinase PF00069.25 ETZ07356.1 - 0.094 12.1 0.2 0.72 9.2 0.1 2.1 2 0 0 2 2 2 0 Protein kinase domain Acetyltransf_1 PF00583.25 ETZ07357.1 - 6.6e-17 61.8 0.0 8.2e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ETZ07357.1 - 4.2e-13 49.3 0.1 6e-13 48.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ETZ07357.1 - 4.9e-13 49.3 0.0 9.9e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ETZ07357.1 - 1.5e-07 32.2 0.0 1.8e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ETZ07357.1 - 3.3e-07 30.4 0.0 3.9e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ETZ07357.1 - 5.3e-07 29.9 0.1 7.3e-07 29.5 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ETZ07357.1 - 0.00029 20.9 0.0 0.0005 20.2 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase IF3_N PF05198.16 ETZ07357.1 - 0.00086 19.5 0.0 0.0015 18.7 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain FR47 PF08445.10 ETZ07357.1 - 0.042 13.8 0.0 0.063 13.3 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein NUDIX PF00293.28 ETZ07358.1 - 3.5e-13 49.7 0.0 4.5e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Peptidase_S24 PF00717.23 ETZ07359.1 - 3.1e-09 36.7 0.1 4.8e-09 36.0 0.1 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 ETZ07359.1 - 5.2e-05 23.1 0.0 7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 Acetyltransf_8 PF13523.6 ETZ07360.1 - 1e-17 64.1 0.0 1.4e-15 57.2 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETZ07360.1 - 1.8e-12 47.5 0.7 2.3e-08 34.3 0.1 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ETZ07360.1 - 2.8e-11 43.4 0.6 3.7e-08 33.4 0.1 2.6 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ETZ07360.1 - 3.9e-10 40.5 0.0 1.7e-09 38.5 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ETZ07360.1 - 8.1e-10 39.0 0.8 2.4e-07 31.1 0.1 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain DUF4440 PF14534.6 ETZ07360.1 - 0.00012 22.4 0.2 0.0003 21.2 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) NTP_transf_2 PF01909.23 ETZ07360.1 - 0.0067 16.7 0.0 0.02 15.1 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 ETZ07360.1 - 0.0095 16.0 0.0 0.034 14.2 0.0 2.0 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Acetyltransf_13 PF13880.6 ETZ07360.1 - 0.16 12.0 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase CPT PF07931.12 ETZ07361.1 - 9.3e-09 35.4 0.0 1e-08 35.2 0.0 1.0 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein CPT PF07931.12 ETZ07362.1 - 1.9e-18 66.9 0.0 2.3e-18 66.6 0.0 1.0 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein NB-ARC PF00931.22 ETZ07362.1 - 0.015 14.5 0.0 0.024 13.8 0.0 1.5 1 1 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.12 ETZ07362.1 - 0.067 12.5 0.0 0.16 11.3 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 ETZ07362.1 - 0.098 13.2 0.0 0.11 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 ETZ07362.1 - 0.12 12.4 0.1 0.95 9.5 0.1 2.0 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 ETZ07362.1 - 0.22 11.4 0.0 0.32 10.9 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase MarR PF01047.22 ETZ07363.1 - 3e-12 46.3 0.3 6.4e-12 45.2 0.3 1.6 1 1 0 1 1 1 1 MarR family HTH_27 PF13463.6 ETZ07363.1 - 3.5e-09 37.0 0.1 5.1e-09 36.5 0.1 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR_2 PF12802.7 ETZ07363.1 - 2e-07 30.8 0.0 3.1e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 ETZ07363.1 - 0.00031 20.7 0.1 0.0011 18.9 0.0 1.8 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_24 PF13412.6 ETZ07363.1 - 0.0024 17.4 0.1 0.0051 16.3 0.0 1.6 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding PadR PF03551.14 ETZ07363.1 - 0.017 15.1 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Rrf2 PF02082.20 ETZ07363.1 - 0.045 14.1 0.0 0.075 13.4 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator Phage_rep_O PF04492.13 ETZ07363.1 - 0.052 14.1 0.1 0.36 11.4 0.1 2.0 1 1 1 2 2 2 0 Bacteriophage replication protein O TFIIE_alpha PF02002.17 ETZ07363.1 - 0.071 13.0 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 TFIIE alpha subunit DUF655 PF04919.12 ETZ07363.1 - 0.072 13.0 0.0 0.085 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF655) Fe_dep_repress PF01325.19 ETZ07363.1 - 0.075 13.2 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain MerR PF00376.23 ETZ07363.1 - 0.1 12.3 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 MerR family regulatory protein adh_short PF00106.25 ETZ07364.1 - 1.7e-30 105.9 0.0 2.2e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETZ07364.1 - 1.9e-21 76.7 0.0 2.1e-21 76.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ETZ07364.1 - 1.7e-06 27.7 0.0 4.4e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 ETZ07364.1 - 2.6e-06 27.5 0.0 3.8e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 ETZ07364.1 - 0.00021 20.4 0.0 0.0024 16.9 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 ETZ07364.1 - 0.00027 20.9 0.0 0.00054 19.9 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 ETZ07364.1 - 0.012 15.0 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase GrpB PF04229.14 ETZ07366.1 - 8.8e-44 149.5 0.0 1.4e-43 148.8 0.0 1.3 1 0 0 1 1 1 1 GrpB protein Acetyltransf_1 PF00583.25 ETZ07366.1 - 6.1e-10 39.4 0.2 1.6e-09 38.0 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ETZ07366.1 - 3.4e-05 24.2 0.0 6.8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ETZ07366.1 - 0.00011 22.1 0.0 0.00022 21.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ETZ07367.1 - 9.2e-16 58.0 0.4 3.4e-07 30.6 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETZ07367.1 - 1.1e-15 57.8 0.4 1.5e-06 28.5 0.1 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ETZ07367.1 - 7.6e-11 42.1 0.1 0.00071 19.5 0.0 2.8 2 2 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 ETZ07367.1 - 6.7e-05 22.5 0.0 0.0015 18.0 0.2 2.0 1 1 0 2 2 2 1 Putative acetyl-transferase Acetyltransf_CG PF14542.6 ETZ07367.1 - 0.014 15.5 0.0 1.8 8.7 0.0 2.4 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 ETZ07367.1 - 0.018 15.0 0.0 1.8 8.6 0.0 2.7 2 1 0 2 2 2 0 FR47-like protein Acetyltransf_6 PF13480.7 ETZ07367.1 - 0.027 14.6 0.0 0.17 12.1 0.0 2.2 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Luteo_coat PF00894.18 ETZ07367.1 - 0.059 13.3 0.0 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 Luteovirus coat protein Acetyltransf_13 PF13880.6 ETZ07367.1 - 0.099 12.6 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Gly_kinase PF02595.15 ETZ07367.1 - 0.16 10.9 0.4 0.24 10.4 0.4 1.2 1 0 0 1 1 1 0 Glycerate kinase family MerR_1 PF13411.6 ETZ07368.1 - 1.3e-17 63.6 0.1 2.9e-17 62.5 0.1 1.7 1 0 0 1 1 1 1 MerR HTH family regulatory protein TipAS PF07739.13 ETZ07368.1 - 5.1e-17 62.5 2.8 1e-16 61.5 2.8 1.5 1 0 0 1 1 1 1 TipAS antibiotic-recognition domain MerR PF00376.23 ETZ07368.1 - 9.3e-13 47.7 0.0 1.8e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 MerR family regulatory protein MerR-DNA-bind PF09278.11 ETZ07368.1 - 6.4e-05 23.4 3.7 0.00038 20.9 1.4 2.5 2 0 0 2 2 2 1 MerR, DNA binding HTH_17 PF12728.7 ETZ07368.1 - 0.00014 21.9 0.0 0.0058 16.8 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain DUF4094 PF13334.6 ETZ07368.1 - 0.005 17.2 0.3 0.062 13.7 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4094) FRG PF08867.11 ETZ07368.1 - 0.042 14.8 1.9 0.28 12.2 1.9 2.4 1 1 0 1 1 1 0 FRG domain TetR_N PF00440.23 ETZ07368.1 - 0.081 12.7 0.1 0.2 11.5 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family DUF4972 PF16342.5 ETZ07368.1 - 0.18 11.5 2.7 5.7 6.6 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4972) Cyclase PF04199.13 ETZ07369.1 - 1.2e-32 113.0 0.1 1.4e-32 112.8 0.1 1.1 1 0 0 1 1 1 1 Putative cyclase AAA_28 PF13521.6 ETZ07370.1 - 6.6e-25 88.2 0.0 7.6e-25 88.0 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ETZ07370.1 - 3.9e-07 30.7 0.0 5.8e-07 30.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ETZ07370.1 - 0.00014 22.1 0.0 0.00031 21.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 ETZ07370.1 - 0.00046 20.6 0.0 0.079 13.4 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.10 ETZ07370.1 - 0.003 17.1 0.0 0.0042 16.6 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Viral_helicase1 PF01443.18 ETZ07370.1 - 0.0053 16.5 0.0 0.0074 16.0 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 ETZ07370.1 - 0.011 15.8 0.0 0.022 14.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 ETZ07370.1 - 0.012 15.1 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 ETZ07370.1 - 0.013 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 ETZ07370.1 - 0.019 14.7 0.2 0.063 13.0 0.1 1.7 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 ETZ07370.1 - 0.027 14.6 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 ETZ07370.1 - 0.028 13.3 0.1 0.036 13.0 0.1 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain RuvB_N PF05496.12 ETZ07370.1 - 0.036 13.8 0.0 0.073 12.8 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 ETZ07370.1 - 0.036 14.4 0.0 0.059 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ETZ07370.1 - 0.044 14.2 0.0 0.062 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 ETZ07370.1 - 0.046 13.4 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 ETZ07370.1 - 0.053 13.4 0.1 2.1 8.2 0.0 2.3 1 1 1 2 2 2 0 Adenylylsulphate kinase AAA_17 PF13207.6 ETZ07370.1 - 0.11 12.9 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain LysE PF01810.18 ETZ07371.1 - 8.9e-25 87.3 12.9 1e-24 87.0 12.9 1.0 1 0 0 1 1 1 1 LysE type translocator TerC PF03741.16 ETZ07371.1 - 0.00067 19.4 9.0 0.00082 19.1 8.4 1.6 1 1 0 1 1 1 1 Integral membrane protein TerC family DUF3487 PF11990.8 ETZ07371.1 - 0.027 14.3 1.1 0.027 14.3 1.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3487) AsnC_trans_reg PF01037.21 ETZ07372.1 - 3.3e-15 55.8 0.1 1e-14 54.3 0.0 1.7 2 0 0 2 2 2 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 ETZ07372.1 - 2.7e-09 36.4 0.0 4.3e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 ETZ07372.1 - 5.2e-09 35.8 0.2 8.2e-09 35.2 0.2 1.3 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain MarR PF01047.22 ETZ07372.1 - 0.0012 18.8 0.1 0.0025 17.7 0.1 1.6 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 ETZ07372.1 - 0.0019 18.0 0.1 0.0035 17.2 0.1 1.4 1 0 0 1 1 1 1 MarR family LexA_DNA_bind PF01726.16 ETZ07372.1 - 0.0086 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 LexA DNA binding domain TrmB PF01978.19 ETZ07372.1 - 0.016 15.1 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Ribosomal_S25 PF03297.15 ETZ07372.1 - 0.04 14.1 0.1 0.084 13.1 0.1 1.5 1 0 0 1 1 1 0 S25 ribosomal protein HTH_11 PF08279.12 ETZ07372.1 - 0.052 13.5 0.1 0.093 12.7 0.1 1.4 1 0 0 1 1 1 0 HTH domain HTH_20 PF12840.7 ETZ07372.1 - 0.067 13.3 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_5 PF01022.20 ETZ07372.1 - 0.068 13.0 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_10 PF04967.12 ETZ07372.1 - 0.12 12.1 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 HTH DNA binding domain ABC_tran PF00005.27 ETZ07373.1 - 2.3e-18 67.0 0.4 1.1e-17 64.8 0.1 2.2 2 1 0 2 2 2 1 ABC transporter SMC_N PF02463.19 ETZ07373.1 - 2.3e-09 37.0 3.3 1.4e-06 27.9 0.1 2.5 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ETZ07373.1 - 1.4e-05 25.0 3.9 0.026 14.3 0.2 2.7 1 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 ETZ07373.1 - 0.00086 19.3 0.1 1.4 8.9 0.0 2.2 2 0 0 2 2 2 2 NACHT domain AAA_29 PF13555.6 ETZ07373.1 - 0.001 18.8 0.1 0.0022 17.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 ETZ07373.1 - 0.0057 16.9 0.0 0.031 14.5 0.0 2.1 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 ETZ07373.1 - 0.0086 16.6 1.0 0.033 14.7 0.0 2.2 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.15 ETZ07373.1 - 0.022 14.7 0.5 3.6 7.5 0.3 2.3 2 0 0 2 2 2 0 NTPase AAA_22 PF13401.6 ETZ07373.1 - 0.043 14.1 0.1 0.095 13.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 ETZ07373.1 - 0.052 12.6 0.0 0.097 11.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein MMR_HSR1 PF01926.23 ETZ07373.1 - 0.062 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_15 PF13175.6 ETZ07373.1 - 0.078 12.7 0.5 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain 30K_MP_core PF17644.1 ETZ07373.1 - 0.11 12.4 0.1 0.27 11.1 0.0 1.6 1 1 0 1 1 1 0 Core domain of 30K viral movement proteins CobA_CobO_BtuR PF02572.15 ETZ07373.1 - 0.11 12.7 1.0 0.12 12.6 0.1 1.5 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP ABC_tran PF00005.27 ETZ07374.1 - 1.8e-21 77.1 0.3 1.9e-12 47.8 0.0 2.8 2 1 1 3 3 3 2 ABC transporter AAA_21 PF13304.6 ETZ07374.1 - 2.5e-14 53.8 1.9 2.4e-07 30.9 0.1 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ETZ07374.1 - 1.3e-07 31.3 0.1 0.0021 17.5 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_tran_Xtn PF12848.7 ETZ07374.1 - 5.7e-05 23.1 0.2 9.6e-05 22.3 0.2 1.4 1 0 0 1 1 1 1 ABC transporter AAA_15 PF13175.6 ETZ07374.1 - 7e-05 22.7 0.1 0.00026 20.8 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 ETZ07374.1 - 0.0006 20.0 0.1 0.0021 18.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 ETZ07374.1 - 0.0011 18.8 0.1 0.025 14.3 0.1 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 ETZ07374.1 - 0.0013 19.3 0.1 0.01 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 ETZ07374.1 - 0.0062 16.8 0.0 0.018 15.2 0.0 1.8 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 ETZ07374.1 - 0.007 16.6 0.8 0.04 14.2 0.8 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 ETZ07374.1 - 0.0073 16.7 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF5082 PF16888.5 ETZ07374.1 - 0.0084 16.4 0.1 0.014 15.7 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) AAA_18 PF13238.6 ETZ07374.1 - 0.0093 16.5 0.0 0.019 15.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ETZ07374.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 ETZ07374.1 - 0.014 15.7 0.1 0.035 14.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 ETZ07374.1 - 0.021 14.6 0.1 0.27 10.9 0.1 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ETZ07374.1 - 0.023 14.6 0.4 0.038 13.9 0.4 1.7 1 1 0 1 1 1 0 NACHT domain SRPRB PF09439.10 ETZ07374.1 - 0.025 14.0 0.3 3.4 7.1 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF3958 PF13125.6 ETZ07374.1 - 0.035 14.3 0.3 0.11 12.7 0.1 1.7 1 1 0 2 2 2 0 Protein of unknown function (DUF3958) MYO10_CC PF16735.5 ETZ07374.1 - 0.06 13.5 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Unconventional myosin-X coiled coil domain MMR_HSR1 PF01926.23 ETZ07374.1 - 0.061 13.4 0.2 0.092 12.8 0.2 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase DLIC PF05783.11 ETZ07374.1 - 0.073 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 ETZ07374.1 - 0.11 12.9 0.5 0.53 10.6 0.5 2.3 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 ETZ07374.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 ETZ07374.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 ETZ07374.1 - 0.15 11.7 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 ETZ07374.1 - 0.15 11.2 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain YcaO PF02624.16 ETZ07375.1 - 0.13 11.5 0.1 0.13 11.6 0.1 1.0 1 0 0 1 1 1 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding DUF1435 PF07256.12 ETZ07376.1 - 0.045 13.8 0.3 0.051 13.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1435) MPC PF03650.13 ETZ07376.1 - 0.058 13.5 0.4 0.11 12.7 0.3 1.5 1 1 1 2 2 2 0 Mitochondrial pyruvate carriers Glyco_hydro_108 PF05838.12 ETZ07377.1 - 1.1e-20 73.9 0.1 1.7e-20 73.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase 108 Phage_GPD PF05954.11 ETZ07378.1 - 5.1e-17 62.1 0.0 6.5e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Phage late control gene D protein (GPD) Phage_tail_X PF05489.12 ETZ07379.1 - 4.7e-22 77.4 0.0 5.7e-22 77.1 0.0 1.0 1 0 0 1 1 1 1 Phage Tail Protein X Phage_P2_GpU PF06995.11 ETZ07380.1 - 1.4e-29 102.2 0.0 1.5e-29 102.1 0.0 1.0 1 0 0 1 1 1 1 Phage P2 GpU PhageMin_Tail PF10145.9 ETZ07381.1 - 1.3e-36 126.3 19.4 1.3e-36 126.3 19.4 3.1 3 1 0 3 3 3 1 Phage-related minor tail protein ESX-1_EspG PF14011.6 ETZ07381.1 - 0.096 12.3 0.0 0.34 10.5 0.0 1.9 1 0 0 1 1 1 0 EspG family DHR10 PF18595.1 ETZ07381.1 - 0.7 10.0 9.8 6.3 6.9 2.6 3.1 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain DUF724 PF05266.14 ETZ07381.1 - 1.9 8.3 6.8 0.12 12.2 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Phage_TAC_7 PF10109.9 ETZ07382.1 - 2.1e-21 75.8 0.1 2.4e-21 75.7 0.1 1.0 1 0 0 1 1 1 1 Phage tail assembly chaperone proteins, E, or 41 or 14 Phage_tube PF04985.14 ETZ07383.1 - 1.1e-58 197.6 0.0 1.2e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Phage tail tube protein FII Phage_sheath_1 PF04984.14 ETZ07384.1 - 2.8e-24 85.9 0.1 4.2e-24 85.3 0.1 1.2 1 0 0 1 1 1 1 Phage tail sheath protein subtilisin-like domain Phage_sheath_1C PF17482.2 ETZ07384.1 - 5.3e-17 61.7 0.0 9.7e-17 60.9 0.0 1.4 1 0 0 1 1 1 1 Phage tail sheath C-terminal domain Herpes_TK_C PF08465.10 ETZ07386.1 - 0.67 9.7 2.6 26 4.7 0.4 2.6 2 0 0 2 2 2 0 Thymidine kinase from Herpesvirus C-terminal Ribosomal_L29 PF00831.23 ETZ07387.1 - 0.012 15.6 0.0 0.03 14.3 0.0 1.8 1 0 0 1 1 1 0 Ribosomal L29 protein NPV_P10 PF05531.12 ETZ07387.1 - 0.44 11.0 10.3 24 5.5 0.0 3.3 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4815 PF16075.5 ETZ07389.1 - 5.5e-174 579.6 0.4 6.4e-174 579.4 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4815) Tail_P2_I PF09684.10 ETZ07391.1 - 2.8e-10 40.2 0.0 4.5e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Phage tail protein (Tail_P2_I) Leader_CPA1 PF08252.11 ETZ07391.1 - 0.042 13.2 4.1 3 7.3 2.0 2.5 2 0 0 2 2 2 0 arg-2/CPA1 leader peptide Baseplate_J PF04865.14 ETZ07392.1 - 1.6e-20 73.4 0.0 2.4e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Baseplate J-like protein GPW_gp25 PF04965.14 ETZ07393.1 - 5.1e-14 51.8 0.0 6.5e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Gene 25-like lysozyme DUF2634 PF10934.8 ETZ07393.1 - 0.00017 21.7 0.0 0.00021 21.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2634) PAAR_motif PF05488.13 ETZ07394.1 - 7.6e-15 54.9 7.0 2.6e-13 49.9 1.9 2.2 1 1 1 2 2 2 2 PAAR motif DUF4150 PF13665.6 ETZ07394.1 - 0.0019 18.3 0.0 1.1 9.4 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4150) Phage_base_V PF04717.12 ETZ07395.1 - 3.1e-43 146.3 0.0 3.8e-43 146.0 0.0 1.1 1 0 0 1 1 1 1 Type VI secretion system, phage-baseplate injector Minor_tail_Z PF06763.11 ETZ07397.1 - 6.6e-15 55.4 3.7 2.1e-14 53.8 3.7 1.7 1 1 0 1 1 1 1 Prophage minor tail protein Z (GPZ) CsgE PF10627.9 ETZ07398.1 - 0.054 13.7 0.0 0.069 13.4 0.0 1.2 1 0 0 1 1 1 0 Curli assembly protein CsgE Phage_cap_E PF03864.15 ETZ07399.1 - 6.6e-114 380.5 0.0 7.4e-114 380.4 0.0 1.0 1 0 0 1 1 1 1 Phage major capsid protein E HDPD PF02924.14 ETZ07400.1 - 1.7e-34 118.4 3.0 1.9e-34 118.2 3.0 1.0 1 0 0 1 1 1 1 Bacteriophage lambda head decoration protein D Peptidase_S49 PF01343.18 ETZ07401.1 - 6.9e-32 110.5 0.1 1.1e-31 109.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase family S49 CLP_protease PF00574.23 ETZ07401.1 - 4e-06 26.8 0.4 7.8e-05 22.6 0.2 2.5 3 0 0 3 3 3 1 Clp protease Phage_portal_2 PF05136.13 ETZ07402.1 - 2.9e-24 85.9 0.1 5.6e-24 85.0 0.0 1.5 2 0 0 2 2 2 1 Phage portal protein, lambda family Phage_portal_2 PF05136.13 ETZ07403.1 - 9.1e-20 71.1 0.0 1e-19 70.9 0.0 1.0 1 0 0 1 1 1 1 Phage portal protein, lambda family Phage_portal_2 PF05136.13 ETZ07404.1 - 1.8e-19 70.1 0.1 2e-19 70.0 0.1 1.0 1 0 0 1 1 1 1 Phage portal protein, lambda family gpW PF02831.15 ETZ07405.1 - 1.3e-07 31.4 0.1 1.5e-07 31.2 0.1 1.2 1 0 0 1 1 1 1 gpW Terminase_GpA PF05876.12 ETZ07406.1 - 2.3e-197 657.0 0.0 2.7e-197 656.8 0.0 1.0 1 0 0 1 1 1 1 Phage terminase large subunit (GpA) TFIIS_C PF01096.18 ETZ07406.1 - 0.045 13.6 0.2 0.098 12.5 0.2 1.6 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS) N6_N4_Mtase PF01555.18 ETZ07408.1 - 3.1e-18 66.3 0.0 3.7e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 DNA methylase UPF0020 PF01170.18 ETZ07408.1 - 0.0072 16.0 0.0 0.0086 15.8 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 ETZ07408.1 - 0.0076 15.9 0.0 0.0084 15.8 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 ETZ07408.1 - 0.009 15.6 0.0 0.0096 15.5 0.0 1.0 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 ETZ07408.1 - 0.053 13.3 0.0 0.058 13.1 0.0 1.1 1 0 0 1 1 1 0 Met-10+ like-protein HTH_29 PF13551.6 ETZ07408.1 - 0.12 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix LRR_4 PF12799.7 ETZ07409.1 - 4.4e-11 42.8 4.0 6.7e-05 23.2 0.3 4.0 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 ETZ07409.1 - 0.0013 18.3 0.3 0.008 15.7 0.1 2.1 1 1 1 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 ETZ07409.1 - 0.011 15.5 0.4 0.045 13.5 0.4 2.2 1 1 0 1 1 1 0 Leucine rich repeat LPG_synthase_TM PF03706.13 ETZ07410.1 - 1.4e-13 51.0 33.3 1.4e-13 51.0 33.3 4.1 2 1 2 4 4 4 1 Lysylphosphatidylglycerol synthase TM region HeLo PF14479.6 ETZ07411.1 - 0.0077 16.1 0.7 0.0095 15.8 0.7 1.1 1 0 0 1 1 1 1 Prion-inhibition and propagation BLI1 PF17324.2 ETZ07411.1 - 0.032 14.9 2.8 0.54 10.9 0.1 2.2 2 0 0 2 2 2 0 BLOC-1 interactor 1 PAP_central PF04928.17 ETZ07415.1 - 0.03 13.3 0.1 0.069 12.1 0.1 1.5 1 0 0 1 1 1 0 Poly(A) polymerase central domain EF-hand_11 PF08976.11 ETZ07415.1 - 0.11 13.3 3.7 1.8 9.5 0.4 3.5 3 0 0 3 3 3 0 EF-hand domain Peptidase_M50 PF02163.22 ETZ07416.1 - 3.9e-56 190.1 0.0 4.8e-56 189.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M50 PDZ_2 PF13180.6 ETZ07416.1 - 0.00015 22.0 0.1 0.00029 21.1 0.1 1.4 1 0 0 1 1 1 1 PDZ domain Peptidase_M50B PF13398.6 ETZ07416.1 - 0.072 12.7 3.6 0.29 10.8 0.2 2.8 2 1 0 2 2 2 0 Peptidase M50B-like DUF3420 PF11900.8 ETZ07416.1 - 0.099 12.8 0.1 0.23 11.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3420) DUF2633 PF11119.8 ETZ07416.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) Ubie_methyltran PF01209.18 ETZ07418.1 - 8.1e-45 153.0 0.0 9.7e-45 152.7 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 ETZ07418.1 - 6.6e-14 52.4 0.0 9.5e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETZ07418.1 - 6.5e-12 46.0 0.0 1e-11 45.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETZ07418.1 - 3.5e-09 36.6 0.0 4.5e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETZ07418.1 - 1.7e-08 34.5 0.0 2.4e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETZ07418.1 - 0.00013 22.6 0.0 0.00053 20.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ETZ07418.1 - 0.019 14.5 0.0 0.072 12.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain MFS_1 PF07690.16 ETZ07419.1 - 0.00011 21.3 48.5 0.0016 17.5 23.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DDE_3 PF13358.6 ETZ07420.1 - 9.4e-05 22.2 0.5 0.00091 19.0 0.5 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.26 ETZ07421.1 - 1.1e-16 61.1 0.1 1.9e-16 60.3 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 ETZ07421.1 - 3.9e-08 33.0 0.3 8.6e-08 31.8 0.3 1.6 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 ETZ07421.1 - 8.2e-08 32.6 1.7 1.7e-07 31.5 1.7 1.5 1 0 0 1 1 1 1 DDE domain Terminase_5 PF06056.12 ETZ07421.1 - 0.0074 16.2 0.1 0.016 15.1 0.1 1.5 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) Phage_terminase PF10668.9 ETZ07421.1 - 0.022 14.8 0.2 0.046 13.7 0.2 1.5 1 0 0 1 1 1 0 Phage terminase small subunit HTH_23 PF13384.6 ETZ07421.1 - 0.063 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_36 PF13730.6 ETZ07421.1 - 0.072 13.1 0.2 0.23 11.4 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 ETZ07421.1 - 0.084 13.2 0.1 0.22 11.9 0.1 1.6 1 0 0 1 1 1 0 Transposase Frataxin_Cyay PF01491.16 ETZ07422.1 - 1e-15 57.7 0.0 1.2e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain AMNp_N PF10423.9 ETZ07423.1 - 2.8e-26 92.0 0.0 7.4e-26 90.7 0.0 1.7 2 0 0 2 2 2 1 Bacterial AMP nucleoside phosphorylase N-terminus PNP_UDP_1 PF01048.20 ETZ07423.1 - 2.3e-13 50.0 0.0 3.5e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily DNA_gyraseB PF00204.25 ETZ07424.1 - 5.6e-50 169.2 0.0 1.1e-49 168.3 0.0 1.5 1 0 0 1 1 1 1 DNA gyrase B DNA_gyraseB_C PF00986.21 ETZ07424.1 - 5e-27 93.9 0.0 1.1e-26 92.8 0.0 1.6 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 ETZ07424.1 - 4.1e-21 75.6 0.0 7.7e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 ETZ07424.1 - 4.1e-16 59.1 0.0 1.1e-15 57.7 0.0 1.8 1 0 0 1 1 1 1 Toprim domain HATPase_c_3 PF13589.6 ETZ07424.1 - 0.0055 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MlaD PF02470.20 ETZ07425.1 - 2.5e-18 66.2 0.0 3.5e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 MlaD protein COX6C PF02937.15 ETZ07425.1 - 0.1 12.7 0.1 0.43 10.8 0.1 1.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIc DDE_3 PF13358.6 ETZ07426.1 - 1.8e-07 31.0 0.0 1.9e-07 30.9 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_IS630 PF01710.16 ETZ07427.1 - 1.9e-22 79.5 5.1 2.1e-22 79.4 5.1 1.0 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 ETZ07427.1 - 1e-09 38.4 0.1 0.00026 21.1 0.1 2.1 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_23 PF13384.6 ETZ07427.1 - 6.2e-07 29.0 0.1 0.028 14.2 0.0 2.2 2 0 0 2 2 2 2 Homeodomain-like domain PAX PF00292.18 ETZ07427.1 - 1.2e-06 28.4 0.1 2e-06 27.7 0.0 1.3 1 1 0 1 1 1 1 'Paired box' domain HTH_7 PF02796.15 ETZ07427.1 - 8.6e-06 25.7 0.3 0.018 15.1 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 ETZ07427.1 - 1.4e-05 25.0 0.0 0.0023 17.9 0.0 2.1 1 1 1 2 2 2 1 Winged helix-turn helix HTH_Tnp_4 PF13613.6 ETZ07427.1 - 4.9e-05 23.0 0.0 0.027 14.2 0.0 2.3 2 0 0 2 2 2 2 Helix-turn-helix of DDE superfamily endonuclease TnsD PF15978.5 ETZ07427.1 - 0.00014 21.0 0.6 0.00023 20.2 0.6 1.4 1 1 0 1 1 1 1 Tn7-like transposition protein D Sigma70_r4_2 PF08281.12 ETZ07427.1 - 0.0018 17.9 0.0 0.036 13.7 0.0 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_17 PF12728.7 ETZ07427.1 - 0.0032 17.6 0.2 2.4 8.4 0.0 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 ETZ07427.1 - 0.0032 16.8 0.0 0.41 10.1 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_32 PF13565.6 ETZ07427.1 - 0.0033 18.0 0.1 0.023 15.3 0.1 2.1 2 1 0 2 2 2 1 Homeodomain-like domain UPF0122 PF04297.14 ETZ07427.1 - 0.0044 17.2 0.3 0.0097 16.1 0.1 1.7 2 0 0 2 2 2 1 Putative helix-turn-helix protein, YlxM / p13 like HTH_33 PF13592.6 ETZ07427.1 - 0.011 15.4 0.2 0.043 13.4 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_6 PF01418.17 ETZ07427.1 - 0.019 15.0 0.2 0.51 10.4 0.0 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain, rpiR family HTH_11 PF08279.12 ETZ07427.1 - 0.028 14.3 0.1 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 HTH domain Sigma70_r4 PF04545.16 ETZ07427.1 - 0.041 13.4 0.0 0.74 9.4 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_24 PF13412.6 ETZ07427.1 - 0.048 13.2 0.0 0.35 10.5 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_22 PF13309.6 ETZ07427.1 - 0.062 13.4 0.2 0.51 10.5 0.0 2.3 2 0 0 2 2 2 0 HTH domain HTH_38 PF13936.6 ETZ07427.1 - 0.082 12.7 0.1 5.1 6.9 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain TrmB PF01978.19 ETZ07427.1 - 0.093 12.6 0.1 2.9 7.8 0.0 2.2 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB IF2_N PF04760.15 ETZ07427.1 - 0.097 12.5 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region HTH_Crp_2 PF13545.6 ETZ07427.1 - 0.14 12.2 0.0 7.9 6.5 0.0 2.2 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain tRNA_Me_trans PF03054.16 ETZ07428.1 - 8e-100 334.1 0.0 9.1e-100 333.9 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.13 ETZ07428.1 - 0.00013 21.6 0.0 0.00097 18.7 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC NAD_synthase PF02540.17 ETZ07428.1 - 0.00047 19.3 0.0 0.00086 18.5 0.0 1.5 1 0 0 1 1 1 1 NAD synthase ATP_bind_3 PF01171.20 ETZ07428.1 - 0.0095 15.7 0.2 0.098 12.4 0.2 2.2 1 1 0 1 1 1 1 PP-loop family PAPS_reduct PF01507.19 ETZ07428.1 - 0.015 15.4 0.1 0.027 14.5 0.1 1.4 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Asn_synthase PF00733.21 ETZ07428.1 - 0.063 12.9 0.0 0.14 11.8 0.0 1.5 1 1 0 1 1 1 0 Asparagine synthase RMF PF04957.12 ETZ07428.1 - 0.087 13.1 0.1 0.21 11.8 0.1 1.6 1 0 0 1 1 1 0 Ribosome modulation factor Arginosuc_synth PF00764.19 ETZ07428.1 - 0.11 11.7 0.1 0.15 11.3 0.1 1.3 1 1 0 1 1 1 0 Arginosuccinate synthase ThiI PF02568.14 ETZ07428.1 - 0.19 11.3 0.0 0.38 10.3 0.0 1.5 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) DUF948 PF06103.11 ETZ07429.1 - 0.00016 21.9 0.2 0.00064 19.9 0.0 2.0 2 1 0 2 2 2 1 Bacterial protein of unknown function (DUF948) ATP-synt_B PF00430.18 ETZ07429.1 - 0.00017 21.7 1.1 0.00042 20.4 1.0 1.5 1 1 0 1 1 1 1 ATP synthase B/B' CF(0) OmpH PF03938.14 ETZ07429.1 - 0.003 17.9 11.3 0.003 17.9 11.3 2.0 1 1 1 2 2 2 2 Outer membrane protein (OmpH-like) Cortex-I_coil PF09304.10 ETZ07429.1 - 0.0094 16.2 4.4 0.0094 16.2 4.4 1.7 1 1 1 2 2 2 1 Cortexillin I, coiled coil Exonuc_VII_L PF02601.15 ETZ07429.1 - 0.022 14.3 8.3 0.026 14.1 8.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2570 PF10828.8 ETZ07429.1 - 0.42 10.4 6.7 0.14 11.9 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) WXG100 PF06013.12 ETZ07429.1 - 0.86 9.9 11.3 2.9 8.2 5.8 2.4 2 1 0 2 2 2 0 Proteins of 100 residues with WXG 7TMR-HDED PF07697.11 ETZ07429.1 - 0.94 9.6 7.9 1.3 9.1 7.9 1.2 1 0 0 1 1 1 0 7TM-HD extracellular DUF2524 PF10732.9 ETZ07429.1 - 1.3 9.3 16.2 2.5 8.5 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2524) YMF19 PF02326.15 ETZ07430.1 - 6.1e-08 33.3 3.9 2.2e-07 31.6 3.9 2.0 1 1 0 1 1 1 1 Plant ATP synthase F0 DUF883 PF05957.13 ETZ07430.1 - 0.013 16.1 1.8 0.013 16.1 1.8 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Baculo_PEP_C PF04513.12 ETZ07430.1 - 0.23 11.5 6.2 0.64 10.1 5.5 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoO PF09769.9 ETZ07430.1 - 0.23 11.4 0.6 0.34 10.9 0.6 1.4 1 0 0 1 1 1 0 Apolipoprotein O CTI PF06934.11 ETZ07430.1 - 0.35 9.3 7.3 0.43 9.0 7.3 1.0 1 0 0 1 1 1 0 Fatty acid cis/trans isomerase (CTI) Phage_Mu_Gam PF07352.12 ETZ07430.1 - 0.5 10.3 9.4 1.3 8.9 7.8 2.0 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein ATP-synt_C PF00137.21 ETZ07431.1 - 1e-08 35.4 8.9 1.2e-08 35.2 8.9 1.1 1 0 0 1 1 1 1 ATP synthase subunit C DsbB PF02600.16 ETZ07432.1 - 1.3e-13 51.6 16.2 1.6e-13 51.4 16.2 1.1 1 0 0 1 1 1 1 Disulfide bond formation protein DsbB TraC PF07820.12 ETZ07433.1 - 0.027 14.8 0.0 0.038 14.3 0.0 1.2 1 0 0 1 1 1 0 TraC-like protein DEC-1_N PF04625.13 ETZ07433.1 - 0.18 10.8 12.1 0.19 10.7 12.1 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region CAP_N PF01213.19 ETZ07433.1 - 1.7 8.1 6.9 2.4 7.6 6.9 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DDE_3 PF13358.6 ETZ07434.1 - 1.1e-08 35.0 0.1 1.2e-08 34.8 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease PGK PF00162.19 ETZ07434.1 - 0.062 12.3 0.0 0.062 12.3 0.0 1.0 1 0 0 1 1 1 0 Phosphoglycerate kinase DDE_Tnp_1 PF01609.21 ETZ07436.1 - 3.3e-14 53.0 0.9 4.3e-14 52.7 0.9 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_assoc PF13808.6 ETZ07436.1 - 1.3e-06 28.3 0.0 5.1e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 DDE_Tnp_1-associated DnaB_C PF03796.15 ETZ07439.1 - 7.1e-100 333.6 0.1 9.8e-100 333.1 0.1 1.2 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain DnaB PF00772.21 ETZ07439.1 - 8.1e-23 80.5 0.4 2e-22 79.2 0.4 1.7 1 0 0 1 1 1 1 DnaB-like helicase N terminal domain AAA_25 PF13481.6 ETZ07439.1 - 6.8e-16 58.4 0.6 1.1e-15 57.7 0.1 1.6 2 0 0 2 2 2 1 AAA domain Rad51 PF08423.11 ETZ07439.1 - 5.4e-05 22.6 0.5 0.32 10.2 0.0 2.9 3 0 0 3 3 3 2 Rad51 AAA PF00004.29 ETZ07439.1 - 0.036 14.5 0.1 0.2 12.1 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 ETZ07439.1 - 0.058 12.7 1.0 1.4 8.2 0.2 3.1 3 1 0 3 3 3 0 KaiC HTH_Tnp_4 PF13613.6 ETZ07440.1 - 1.6e-09 37.3 0.0 2e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_IS1 PF03400.13 ETZ07441.1 - 3.7e-10 40.2 0.1 4.1e-10 40.1 0.1 1.0 1 0 0 1 1 1 1 IS1 transposase DDE_Tnp_IS240 PF13610.6 ETZ07441.1 - 0.00055 20.2 0.1 0.00064 20.0 0.1 1.1 1 0 0 1 1 1 1 DDE domain rve PF00665.26 ETZ07441.1 - 0.0026 17.9 0.1 0.0031 17.7 0.1 1.1 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.6 ETZ07441.1 - 0.012 15.4 0.0 0.014 15.1 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease DDE_Tnp_IS1595 PF12762.7 ETZ07441.1 - 0.023 14.7 0.0 0.027 14.5 0.0 1.0 1 0 0 1 1 1 0 ISXO2-like transposase domain PLA2_B PF01735.18 ETZ07441.1 - 0.024 13.1 0.0 0.027 12.9 0.0 1.0 1 0 0 1 1 1 0 Lysophospholipase catalytic domain DUF4754 PF15946.5 ETZ07441.1 - 0.028 14.7 0.0 0.037 14.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4754) TPR_16 PF13432.6 ETZ07444.1 - 9.5e-06 26.2 0.0 1.9e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 ETZ07444.1 - 0.00083 19.8 1.4 1.4 9.5 0.0 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 ETZ07444.1 - 0.0025 17.8 4.9 0.087 13.0 0.9 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 ETZ07444.1 - 0.0036 17.1 3.7 0.043 13.6 0.9 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat PknG_TPR PF16918.5 ETZ07444.1 - 0.0044 15.8 0.0 0.0068 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase G tetratricopeptide repeat TPR_21 PF09976.9 ETZ07444.1 - 0.04 13.6 0.2 0.068 12.9 0.2 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain DUF2951 PF11166.8 ETZ07444.1 - 0.16 12.2 0.4 0.16 12.2 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) ANAPC3 PF12895.7 ETZ07444.1 - 0.2 11.9 7.9 0.55 10.5 1.0 2.6 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 ETZ07444.1 - 0.45 11.2 3.3 32 5.5 0.5 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat Sbi-IV PF11621.8 ETZ07444.1 - 0.74 10.2 3.8 1.1 9.6 0.1 2.7 2 1 0 2 2 2 0 C3 binding domain 4 of IgG-bind protein SBI FTSW_RODA_SPOVE PF01098.19 ETZ07445.1 - 1.2e-71 241.6 25.1 1.4e-71 241.4 25.1 1.0 1 0 0 1 1 1 1 Cell cycle protein Otopetrin PF03189.13 ETZ07445.1 - 0.0027 16.6 0.4 0.005 15.7 0.4 1.4 1 0 0 1 1 1 1 Otopetrin Mur_ligase_M PF08245.12 ETZ07446.1 - 6.9e-20 71.9 0.0 1e-19 71.3 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Ribosomal_L35Ae PF01247.18 ETZ07446.1 - 0.011 15.9 0.0 0.024 14.8 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L35Ae Cpn10 PF00166.21 ETZ07447.1 - 6.3e-35 119.1 0.1 6.9e-35 119.0 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cpn60_TCP1 PF00118.24 ETZ07448.1 - 1.2e-92 311.2 10.5 1.7e-92 310.6 10.5 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ChlI PF13541.6 ETZ07448.1 - 0.011 15.5 0.8 12 5.8 0.1 3.2 2 1 1 3 3 3 0 Subunit ChlI of Mg-chelatase Biotin_lipoyl PF00364.22 ETZ07450.1 - 5.3e-16 58.2 0.0 7.6e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.6 ETZ07450.1 - 0.0015 18.5 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl_2 PF13533.6 ETZ07450.1 - 0.0026 17.5 0.0 0.03 14.2 0.0 2.1 2 0 0 2 2 2 1 Biotin-lipoyl like NQRA PF05896.11 ETZ07450.1 - 0.013 14.9 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) XS PF03468.14 ETZ07450.1 - 0.22 11.9 0.1 0.29 11.5 0.1 1.2 1 0 0 1 1 1 0 XS domain DDE_3 PF13358.6 ETZ07451.1 - 0.00018 21.3 0.0 0.00019 21.2 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_IS630 PF01710.16 ETZ07452.1 - 1.4e-09 38.1 0.4 1.9e-09 37.6 0.4 1.4 1 1 0 1 1 1 1 Transposase HTH_23 PF13384.6 ETZ07452.1 - 2.4e-05 24.0 0.0 3.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 ETZ07452.1 - 0.00013 22.0 0.0 0.00019 21.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain PAX PF00292.18 ETZ07452.1 - 0.011 15.6 0.1 0.011 15.6 0.1 1.0 1 0 0 1 1 1 0 'Paired box' domain HTH_29 PF13551.6 ETZ07452.1 - 0.013 15.6 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix HTH_psq PF05225.16 ETZ07452.1 - 0.055 13.2 0.0 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_3 PF01381.22 ETZ07452.1 - 0.068 13.2 0.0 0.095 12.8 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix DDE_Tnp_1 PF01609.21 ETZ07453.1 - 0.0016 18.2 0.0 0.0016 18.1 0.0 1.0 1 0 0 1 1 1 1 Transposase DDE domain DPBB_1 PF03330.18 ETZ07454.1 - 0.098 12.9 0.1 36 4.7 0.0 4.3 4 1 1 5 5 5 0 Lytic transglycolase MA3 PF02847.17 ETZ07454.1 - 7 6.7 10.8 3.5 7.7 0.1 5.3 6 0 0 6 6 6 0 MA3 domain AAA_2 PF07724.14 ETZ07455.1 - 7.2e-56 189.0 0.0 3.8e-54 183.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 ETZ07455.1 - 6.6e-34 116.0 0.5 6.6e-34 116.0 0.5 2.5 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 ETZ07455.1 - 5.7e-24 84.0 0.1 2.8e-23 81.8 0.1 2.3 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 ETZ07455.1 - 7.9e-24 84.6 0.0 2.7e-13 50.5 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ETZ07455.1 - 8.2e-19 68.0 1.2 3.7e-12 46.4 0.0 4.4 3 2 1 4 4 4 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ETZ07455.1 - 1.7e-12 48.0 7.2 2.9e-05 24.5 0.2 4.7 3 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 ETZ07455.1 - 6.7e-10 39.4 4.7 0.0084 16.4 0.1 5.7 5 1 0 5 5 5 2 AAA domain Clp_N PF02861.20 ETZ07455.1 - 1.5e-07 31.4 0.1 4.6e-06 26.7 0.0 3.1 3 0 0 3 3 2 1 Clp amino terminal domain, pathogenicity island component Sigma54_activat PF00158.26 ETZ07455.1 - 1.6e-07 31.2 0.0 0.00059 19.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 ETZ07455.1 - 1.3e-06 28.3 0.0 0.025 14.3 0.0 2.9 2 0 0 2 2 2 2 IstB-like ATP binding protein ATPase_2 PF01637.18 ETZ07455.1 - 1.3e-06 28.5 0.2 0.31 10.9 0.3 3.7 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 ETZ07455.1 - 2.1e-06 27.4 0.0 0.0066 16.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 ETZ07455.1 - 9.6e-06 26.2 0.4 0.21 12.2 0.0 3.5 4 0 0 4 4 2 2 AAA domain Mg_chelatase PF01078.21 ETZ07455.1 - 1.1e-05 25.0 0.1 0.16 11.3 0.0 3.3 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI TniB PF05621.11 ETZ07455.1 - 6.9e-05 22.3 0.0 0.19 11.1 0.0 3.8 2 1 0 2 2 2 1 Bacterial TniB protein RuvB_N PF05496.12 ETZ07455.1 - 7.4e-05 22.6 0.8 1.1 9.0 0.0 3.8 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 ETZ07455.1 - 0.00014 21.6 0.0 0.54 10.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 ETZ07455.1 - 0.00019 21.8 0.1 2 8.7 0.0 3.8 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.6 ETZ07455.1 - 0.00035 20.6 0.0 1.4 9.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 ETZ07455.1 - 0.00043 20.7 0.0 2 8.8 0.0 3.0 3 0 0 3 3 2 2 RNA helicase NACHT PF05729.12 ETZ07455.1 - 0.00045 20.2 0.0 0.27 11.1 0.0 2.9 2 0 0 2 2 2 1 NACHT domain TsaE PF02367.17 ETZ07455.1 - 0.00068 19.6 0.0 1.5 8.8 0.0 2.9 3 0 0 3 3 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 ETZ07455.1 - 0.0013 18.9 0.0 2.7 8.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 ETZ07455.1 - 0.0015 17.8 0.1 0.34 10.0 0.1 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 ETZ07455.1 - 0.0015 18.4 0.0 1.9 8.4 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase Roc PF08477.13 ETZ07455.1 - 0.0017 18.6 0.0 1.7 8.8 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 ETZ07455.1 - 0.0023 17.7 1.0 7 6.3 0.0 4.1 2 1 1 3 3 3 0 AAA domain DNA_pol3_delta2 PF13177.6 ETZ07455.1 - 0.0049 16.7 0.0 0.31 10.8 0.0 2.7 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_3 PF07726.11 ETZ07455.1 - 0.0065 16.3 0.0 4.9 7.0 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SPO22 PF08631.10 ETZ07455.1 - 0.012 15.1 2.8 0.089 12.3 0.1 3.0 3 0 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like AAA_19 PF13245.6 ETZ07455.1 - 0.013 15.9 0.2 0.89 9.9 0.0 3.5 2 1 0 3 3 3 0 AAA domain AAA_25 PF13481.6 ETZ07455.1 - 0.013 15.1 0.2 1 8.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain ResIII PF04851.15 ETZ07455.1 - 0.014 15.4 0.0 25 4.8 0.0 3.8 4 0 0 4 4 3 0 Type III restriction enzyme, res subunit ABC_tran PF00005.27 ETZ07455.1 - 0.022 15.2 0.0 3 8.3 0.0 3.2 2 0 0 2 2 2 0 ABC transporter NTPase_1 PF03266.15 ETZ07455.1 - 0.029 14.3 0.0 6.4 6.6 0.0 3.0 2 0 0 2 2 2 0 NTPase Zeta_toxin PF06414.12 ETZ07455.1 - 0.037 13.3 0.0 10 5.4 0.0 3.2 3 0 0 3 3 2 0 Zeta toxin AAA_29 PF13555.6 ETZ07455.1 - 0.047 13.4 0.0 7.8 6.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 ETZ07455.1 - 0.1 13.1 9.3 0.46 11.0 0.0 3.4 3 1 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.17 ETZ07455.1 - 0.1 12.3 0.0 13 5.5 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF87 PF01935.17 ETZ07455.1 - 1.7 8.6 4.9 2.8 8.0 0.0 3.3 4 0 0 4 4 3 0 Helicase HerA, central domain Mto2_bdg PF12808.7 ETZ07455.1 - 9.5 6.6 8.2 13 6.2 1.7 3.0 3 0 0 3 3 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region PP-binding_2 PF14573.6 ETZ07457.1 - 0.051 13.8 0.0 0.37 11.1 0.0 2.6 1 0 0 1 1 1 0 Acyl-carrier rve PF00665.26 ETZ07459.1 - 0.014 15.6 0.0 0.014 15.6 0.0 1.0 1 0 0 1 1 1 0 Integrase core domain DDE_Tnp_1 PF01609.21 ETZ07459.1 - 0.092 12.4 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Transposase DDE domain Radical_SAM PF04055.21 ETZ07461.1 - 4.3e-11 43.5 0.0 1.2e-10 42.0 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily LIAS_N PF16881.5 ETZ07461.1 - 9.3e-06 26.0 0.1 2.1e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family tRNA-synt_1e PF01406.19 ETZ07462.1 - 3.4e-112 374.7 0.0 4.5e-112 374.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 ETZ07462.1 - 1.2e-10 40.8 0.1 8.4e-05 21.5 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 ETZ07462.1 - 1.2e-07 30.4 0.0 4e-06 25.4 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 ETZ07462.1 - 8.2e-07 28.3 0.0 0.0072 15.3 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (K) DALR_2 PF09190.11 ETZ07462.1 - 0.0041 17.6 0.2 0.057 13.9 0.0 2.5 2 0 0 2 2 2 1 DALR domain tRNA-synt_1b PF00579.25 ETZ07462.1 - 0.094 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) DUF1899 PF08953.11 ETZ07462.1 - 0.13 12.2 0.0 1.5 8.8 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1899) tRNA-synt_1d PF00750.19 ETZ07462.1 - 0.16 10.9 0.8 2.3 7.1 0.0 2.4 3 0 0 3 3 3 0 tRNA synthetases class I (R) Glyco_transf_25 PF01755.17 ETZ07463.1 - 3.4e-18 66.3 0.0 1.2e-16 61.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) TadE PF07811.12 ETZ07463.1 - 2.2 8.7 3.8 6.1 7.2 3.8 1.7 1 0 0 1 1 1 0 TadE-like protein Dicty_CAR PF05462.11 ETZ07464.1 - 0.05 12.7 0.4 0.049 12.8 0.4 1.0 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor MotA_ExbB PF01618.16 ETZ07465.1 - 8.9e-05 22.2 0.1 0.00028 20.6 0.1 1.9 1 1 0 1 1 1 1 MotA/TolQ/ExbB proton channel family Caa3_CtaG PF09678.10 ETZ07465.1 - 0.019 14.5 2.9 0.019 14.5 2.9 1.8 2 0 0 2 2 2 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) Sec34 PF04136.15 ETZ07465.1 - 0.13 12.1 1.2 0.24 11.3 1.2 1.4 1 0 0 1 1 1 0 Sec34-like family MutS_V PF00488.21 ETZ07466.1 - 8.3e-82 273.8 0.1 2.6e-81 272.2 0.0 1.8 2 0 0 2 2 2 1 MutS domain V MutS_I PF01624.20 ETZ07466.1 - 2.6e-42 143.6 0.0 5.2e-41 139.4 0.0 2.4 2 0 0 2 2 2 1 MutS domain I MutS_III PF05192.18 ETZ07466.1 - 1.4e-28 100.5 0.0 2.7e-28 99.5 0.0 1.5 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 ETZ07466.1 - 5.1e-19 68.4 0.6 1.2e-18 67.3 0.2 1.9 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.17 ETZ07466.1 - 7.3e-19 68.4 0.0 1.7e-18 67.3 0.0 1.6 1 0 0 1 1 1 1 MutS domain II AAA_23 PF13476.6 ETZ07466.1 - 0.0091 16.5 3.1 2 8.8 0.0 2.9 3 0 0 3 3 3 2 AAA domain Stathmin PF00836.19 ETZ07466.1 - 0.18 11.8 0.2 0.4 10.6 0.2 1.5 1 0 0 1 1 1 0 Stathmin family Response_reg PF00072.24 ETZ07467.1 - 1.3e-17 63.9 0.0 2.1e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 ETZ07467.1 - 5.3e-14 52.1 0.1 9.5e-14 51.2 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal RRF PF01765.19 ETZ07468.1 - 1.3e-38 132.5 0.7 1.5e-38 132.3 0.7 1.1 1 0 0 1 1 1 1 Ribosome recycling factor Nucleocapsid-N PF11030.8 ETZ07468.1 - 0.057 13.4 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 Nucleocapsid protein N rve PF00665.26 ETZ07471.1 - 0.00071 19.8 0.3 0.14 12.3 0.0 2.1 1 1 1 2 2 2 2 Integrase core domain Acyl_transf_3 PF01757.22 ETZ07472.1 - 0.0018 17.4 35.9 0.0036 16.4 26.5 2.1 1 1 1 2 2 2 2 Acyltransferase family PMAIP1 PF15150.6 ETZ07477.1 - 0.14 12.0 0.5 0.38 10.6 0.1 1.8 1 1 1 2 2 2 0 Phorbol-12-myristate-13-acetate-induced RuvX PF03652.15 ETZ07478.1 - 5.4e-26 91.6 0.0 6.8e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Holliday junction resolvase GreA_GreB_N PF03449.15 ETZ07479.1 - 2.7e-28 97.9 3.4 5.3e-28 97.0 3.4 1.5 1 0 0 1 1 1 1 Transcription elongation factor, N-terminal GreA_GreB PF01272.19 ETZ07479.1 - 1.4e-21 76.1 0.0 2e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term Occludin_ELL PF07303.13 ETZ07479.1 - 0.052 14.3 0.1 0.08 13.7 0.1 1.2 1 0 0 1 1 1 0 Occludin homology domain HTH_27 PF13463.6 ETZ07480.1 - 0.00022 21.7 0.0 0.00079 19.9 0.0 1.9 2 0 0 2 2 2 1 Winged helix DNA-binding domain MarR_2 PF12802.7 ETZ07480.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 MarR family HTH_23 PF13384.6 ETZ07481.1 - 0.011 15.5 0.1 0.011 15.5 0.1 1.1 1 0 0 1 1 1 0 Homeodomain-like domain HTH_10 PF04967.12 ETZ07481.1 - 0.039 13.8 0.0 0.046 13.5 0.0 1.2 1 0 0 1 1 1 0 HTH DNA binding domain Sigma70_r4_2 PF08281.12 ETZ07481.1 - 0.053 13.2 0.0 0.064 12.9 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_28 PF13518.6 ETZ07481.1 - 0.071 13.2 0.1 0.079 13.1 0.1 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain MS_channel PF00924.18 ETZ07482.1 - 1.7e-29 102.9 6.7 2.2e-29 102.5 4.1 2.6 2 0 0 2 2 2 1 Mechanosensitive ion channel T3SSipB PF16535.5 ETZ07482.1 - 0.13 12.7 0.1 0.25 11.8 0.1 1.3 1 0 0 1 1 1 0 Type III cell invasion protein SipB DUF1657 PF07870.11 ETZ07482.1 - 1.4 8.8 5.6 1.9 8.4 2.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1657) Ldh_1_N PF00056.23 ETZ07484.1 - 1.1e-29 103.4 0.1 1.5e-29 102.9 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 ETZ07484.1 - 4.1e-23 82.1 0.0 6.7e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 2-Hacid_dh_C PF02826.19 ETZ07484.1 - 0.017 14.5 0.1 0.031 13.6 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 ETZ07484.1 - 0.039 14.5 1.6 0.13 12.9 1.5 2.1 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 ETZ07484.1 - 0.048 13.6 0.1 0.095 12.6 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NifU_N PF01592.16 ETZ07485.1 - 1.1e-49 167.8 0.1 1.3e-49 167.6 0.1 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain CO_deh_flav_C PF03450.17 ETZ07485.1 - 0.065 13.4 0.1 0.13 12.4 0.0 1.5 2 0 0 2 2 2 0 CO dehydrogenase flavoprotein C-terminal domain Aminotran_5 PF00266.19 ETZ07486.1 - 1.1e-74 251.7 0.0 1.4e-74 251.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 ETZ07486.1 - 5e-06 26.0 0.0 7.6e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 ETZ07486.1 - 0.00014 21.3 0.0 0.0002 20.8 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_3 PF00202.21 ETZ07486.1 - 0.083 11.5 0.2 0.4 9.3 0.1 1.9 2 0 0 2 2 2 0 Aminotransferase class-III MurJ PF03023.14 ETZ07487.1 - 1.1e-69 235.3 30.7 1.3e-69 235.0 30.7 1.1 1 0 0 1 1 1 1 Lipid II flippase MurJ Polysacc_synt_C PF14667.6 ETZ07487.1 - 0.0093 16.0 15.7 0.0093 16.0 15.7 3.7 4 1 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain SpoVS PF04232.12 ETZ07487.1 - 0.093 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Stage V sporulation protein S (SpoVS) DUF4738 PF15889.5 ETZ07488.1 - 0.038 13.8 0.1 0.051 13.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4738) Na_H_Exchanger PF00999.21 ETZ07489.1 - 9.1e-45 153.1 44.0 1.2e-44 152.7 44.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 ETZ07489.1 - 2.2e-17 63.4 0.0 3.7e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain AAA_31 PF13614.6 ETZ07491.1 - 4.7e-59 199.3 0.1 6.3e-59 198.9 0.1 1.2 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 ETZ07491.1 - 2.6e-27 95.4 0.0 3.5e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 ETZ07491.1 - 2.6e-14 53.3 0.0 6.4e-14 52.0 0.0 1.6 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ParA PF10609.9 ETZ07491.1 - 4.4e-11 42.7 0.1 4.1e-09 36.2 0.0 2.4 2 1 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase MipZ PF09140.11 ETZ07491.1 - 5.2e-11 42.3 0.3 2.3e-06 27.1 0.4 2.1 2 0 0 2 2 2 2 ATPase MipZ Fer4_NifH PF00142.18 ETZ07491.1 - 5e-09 36.0 0.1 1.1e-06 28.3 0.0 2.1 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 ETZ07491.1 - 7.2e-07 28.7 2.3 1.7e-06 27.5 0.5 2.2 2 1 0 2 2 2 1 Anion-transporting ATPase SRP54 PF00448.22 ETZ07491.1 - 0.0013 18.4 0.4 0.047 13.3 0.3 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain BTB_3 PF16017.5 ETZ07491.1 - 0.011 15.8 0.0 0.13 12.4 0.0 2.3 2 0 0 2 2 2 0 BTB/POZ domain VirC1 PF07015.11 ETZ07491.1 - 0.025 13.9 0.2 0.058 12.7 0.1 1.8 1 1 1 2 2 2 0 VirC1 protein CLP1_P PF16575.5 ETZ07491.1 - 0.028 14.2 0.1 0.32 10.7 0.0 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Glyco_trans_1_4 PF13692.6 ETZ07491.1 - 0.045 14.2 0.0 0.089 13.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 DUF4096 PF13340.6 ETZ07492.1 - 3.7e-07 30.3 0.0 4e-07 30.2 0.0 1.0 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) FixO PF02433.15 ETZ07493.1 - 0.091 12.2 0.3 0.093 12.2 0.3 1.0 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO Hepatitis_core PF00906.20 ETZ07493.1 - 0.15 11.6 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Hepatitis core antigen PocR PF10114.9 ETZ07493.1 - 0.31 10.8 2.0 0.28 11.0 0.2 1.7 1 1 1 2 2 2 0 Sensory domain found in PocR FERM_N PF09379.10 ETZ07494.1 - 0.085 12.8 0.1 1.1 9.3 0.1 2.5 2 0 0 2 2 2 0 FERM N-terminal domain HATPase_c PF02518.26 ETZ07495.1 - 6.7e-18 65.2 0.0 1.3e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ETZ07495.1 - 7.9e-06 25.8 0.0 3.1e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 ETZ07495.1 - 2.2e-05 24.7 0.3 2.2e-05 24.7 0.3 1.8 2 0 0 2 2 2 1 HAMP domain HATPase_c_3 PF13589.6 ETZ07495.1 - 2.9e-05 23.9 0.0 5.6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 ETZ07495.1 - 0.0018 18.2 0.0 0.0056 16.6 0.0 1.8 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 ETZ07495.1 - 0.046 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain PhoR PF11808.8 ETZ07495.1 - 0.049 14.0 0.1 0.1 13.1 0.1 1.4 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR RelA_SpoT PF04607.17 ETZ07496.1 - 0.00097 19.4 0.3 0.0044 17.3 0.3 2.1 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins HD PF01966.22 ETZ07496.1 - 0.21 11.8 0.5 12 6.2 0.0 3.2 3 0 0 3 3 3 0 HD domain DNA_ligase_aden PF01653.18 ETZ07497.1 - 5.7e-98 327.9 0.0 7.9e-98 327.4 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 ETZ07497.1 - 1.1e-31 108.6 1.5 2.3e-31 107.5 1.5 1.6 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain HHH_2 PF12826.7 ETZ07497.1 - 5.5e-14 52.0 0.1 1.3e-13 50.8 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 ETZ07497.1 - 1.1e-09 38.8 0.0 0.00033 21.2 0.0 2.5 2 0 0 2 2 2 2 Helix-hairpin-helix domain BRCT PF00533.26 ETZ07497.1 - 2.3e-09 37.5 0.0 1.7e-08 34.7 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_ZBD PF03119.16 ETZ07497.1 - 1.1e-08 34.9 3.7 2.1e-08 34.1 3.7 1.5 1 0 0 1 1 1 1 NAD-dependent DNA ligase C4 zinc finger domain PTCB-BRCT PF12738.7 ETZ07497.1 - 0.00041 20.2 0.1 0.00096 19.1 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain HTH_Tnp_IS630 PF01710.16 ETZ07498.1 - 0.092 12.8 0.0 0.097 12.7 0.0 1.1 1 0 0 1 1 1 0 Transposase DUF3038 PF11237.8 ETZ07499.1 - 0.00062 19.8 1.6 0.0097 16.0 0.2 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF3038) ThiD2 PF17792.1 ETZ07499.1 - 0.02 15.3 0.2 0.056 13.9 0.2 1.7 1 0 0 1 1 1 0 ThiD2 family VIT1 PF01988.19 ETZ07499.1 - 0.062 13.2 0.4 0.13 12.2 0.1 1.7 1 1 1 2 2 2 0 VIT family DUF2232 PF09991.9 ETZ07499.1 - 0.22 10.7 2.2 0.47 9.6 0.2 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2232) CIDR1_gamma PF18562.1 ETZ07499.1 - 0.86 9.7 6.5 0.32 11.1 0.9 2.9 2 0 0 2 2 2 0 Cysteine-Rich Interdomain Region 1 gamma SAS4 PF15460.6 ETZ07500.1 - 0.016 15.3 6.8 4.8 7.3 0.2 4.5 2 2 1 4 4 4 0 Something about silencing, SAS, complex subunit 4 PABP PF00658.18 ETZ07500.1 - 3.8 7.8 6.0 9.6 6.5 0.0 3.8 3 1 0 3 3 3 0 Poly-adenylate binding protein, unique domain DDE_Tnp_1 PF01609.21 ETZ07501.1 - 1.9e-07 30.9 0.1 2.3e-07 30.7 0.1 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_4 PF13701.6 ETZ07501.1 - 0.03 12.6 0.5 0.031 12.6 0.5 1.0 1 0 0 1 1 1 0 Transposase DDE domain group 1 Pre-PUA PF17832.1 ETZ07501.1 - 0.061 14.0 0.5 0.074 13.8 0.5 1.1 1 0 0 1 1 1 0 Pre-PUA-like domain RecJ_OB PF17768.1 ETZ07502.1 - 2.9e-16 59.6 0.0 6.4e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 RecJ OB domain DHHA1 PF02272.19 ETZ07502.1 - 1.4e-15 57.9 0.0 2.3e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 DHHA1 domain DHH PF01368.20 ETZ07502.1 - 1.7e-09 37.8 0.0 2.9e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 DHH family DeoRC PF00455.22 ETZ07502.1 - 0.15 12.0 0.1 10 6.1 0.0 2.3 2 0 0 2 2 2 0 DeoR C terminal sensor domain Hydantoinase_A PF01968.18 ETZ07502.1 - 0.16 11.2 0.0 0.32 10.2 0.0 1.4 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase Glycos_transf_1 PF00534.20 ETZ07503.1 - 2.6e-29 101.9 0.0 6.7e-29 100.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ETZ07503.1 - 8.7e-23 81.2 0.0 1.3e-22 80.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 ETZ07503.1 - 6.9e-11 42.3 0.0 1.1e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 ETZ07503.1 - 0.0028 18.0 0.0 0.0063 16.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ETZ07503.1 - 0.0082 16.2 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 rve_3 PF13683.6 ETZ07504.1 - 1.3e-09 37.6 0.2 1.7e-09 37.3 0.2 1.2 1 0 0 1 1 1 1 Integrase core domain rve PF00665.26 ETZ07504.1 - 4.7e-05 23.6 0.1 7.1e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 ETZ07504.1 - 0.03 14.5 0.6 0.043 14.0 0.6 1.1 1 0 0 1 1 1 0 DDE domain RecO_N PF11967.8 ETZ07505.1 - 4.4e-08 33.0 0.0 2.3e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 Recombination protein O N terminal RecO_C PF02565.15 ETZ07505.1 - 0.0088 15.9 0.3 0.014 15.2 0.3 1.2 1 0 0 1 1 1 1 Recombination protein O C terminal RuvC PF02075.17 ETZ07506.1 - 4.8e-36 123.9 0.0 5.5e-36 123.7 0.0 1.0 1 0 0 1 1 1 1 Crossover junction endodeoxyribonuclease RuvC DUF5446 PF17522.2 ETZ07506.1 - 0.2 11.8 0.0 0.4 10.9 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5446) Pyr_redox_2 PF07992.14 ETZ07507.1 - 2e-43 148.7 0.2 2.3e-43 148.5 0.2 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETZ07507.1 - 1.8e-21 76.7 1.2 1.1e-17 64.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETZ07507.1 - 1e-16 61.2 1.7 2.9e-13 50.2 0.2 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETZ07507.1 - 6.8e-08 32.0 3.9 0.00077 18.6 0.2 2.6 2 1 0 3 3 3 2 FAD binding domain DAO PF01266.24 ETZ07507.1 - 1.6e-07 31.2 4.7 0.022 14.3 0.7 3.6 3 1 1 4 4 4 2 FAD dependent oxidoreductase HI0933_like PF03486.14 ETZ07507.1 - 4.3e-07 29.0 0.9 0.06 12.0 0.1 4.0 4 0 0 4 4 4 2 HI0933-like protein NAD_binding_8 PF13450.6 ETZ07507.1 - 1.5e-06 28.3 0.3 2.3e-05 24.5 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 ETZ07507.1 - 4.5e-06 26.2 2.4 0.00022 20.6 0.2 2.4 3 0 0 3 3 3 2 FAD binding domain GIDA PF01134.22 ETZ07507.1 - 1.4e-05 24.4 5.3 0.0022 17.2 0.2 3.9 3 2 1 4 4 4 2 Glucose inhibited division protein A FMO-like PF00743.19 ETZ07507.1 - 0.00045 18.8 0.0 0.00064 18.3 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_Gly3P_dh_N PF01210.23 ETZ07507.1 - 0.00086 19.3 0.2 1.2 9.1 0.0 2.3 2 0 0 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_oxidored PF12831.7 ETZ07507.1 - 0.00089 18.7 1.4 0.012 14.9 0.1 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 ETZ07507.1 - 0.0024 17.1 3.9 0.042 13.1 0.6 2.9 2 2 1 3 3 3 1 Thi4 family NAD_binding_7 PF13241.6 ETZ07507.1 - 0.0043 17.5 0.1 0.33 11.4 0.0 2.5 2 1 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 ETZ07507.1 - 0.0074 16.4 0.8 0.093 12.8 0.0 2.8 4 0 0 4 4 3 1 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.6 ETZ07507.1 - 0.04 13.1 1.1 0.18 10.9 0.0 2.4 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 ETZ07507.1 - 0.63 8.8 3.0 2.1 7.1 0.5 2.3 3 0 0 3 3 3 0 Tryptophan halogenase NAD_binding_9 PF13454.6 ETZ07507.1 - 0.97 9.4 4.9 30 4.6 0.4 3.4 4 0 0 4 4 4 0 FAD-NAD(P)-binding ApbA PF02558.16 ETZ07507.1 - 1.1 8.9 3.2 12 5.5 0.5 2.5 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA DDE_3 PF13358.6 ETZ07509.1 - 3.5e-15 56.0 0.2 4e-15 55.8 0.2 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.26 ETZ07509.1 - 0.0014 18.8 0.0 0.0019 18.4 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Golgin_A5 PF09787.9 ETZ07509.1 - 0.038 13.4 0.0 0.069 12.6 0.0 1.4 2 0 0 2 2 2 0 Golgin subfamily A member 5 rve_3 PF13683.6 ETZ07509.1 - 0.046 13.5 0.0 0.071 12.9 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain NDUF_B6 PF09782.9 ETZ07509.1 - 0.17 12.0 0.1 0.21 11.7 0.1 1.1 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit Ytp1 PF10355.9 ETZ07512.1 - 0.014 14.6 0.0 0.014 14.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (Ytp1) DDE_3 PF13358.6 ETZ07513.1 - 3.6e-16 59.2 0.1 3.7e-16 59.2 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease BRX_N PF13713.6 ETZ07513.1 - 0.07 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain Hexapep PF00132.24 ETZ07514.1 - 9.1e-18 63.2 22.6 6.6e-06 25.6 1.3 6.0 3 2 3 6 6 6 6 Bacterial transferase hexapeptide (six repeats) Acetyltransf_11 PF13720.6 ETZ07514.1 - 9.2e-15 54.9 0.3 1.5e-14 54.2 0.3 1.3 1 0 0 1 1 1 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Hexapep_2 PF14602.6 ETZ07514.1 - 0.023 14.5 11.4 0.14 12.0 0.3 4.1 4 0 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase DUF4096 PF13340.6 ETZ07515.1 - 1.5e-14 54.0 0.6 3.2e-14 52.9 0.6 1.5 2 0 0 2 2 2 1 Putative transposase of IS4/5 family (DUF4096) PG_isomerase_N PF18353.1 ETZ07518.1 - 0.0076 16.6 2.0 0.14 12.5 0.0 2.5 2 0 0 2 2 2 1 Phosphoglucose isomerase N-terminal domain PG_isomerase_N PF18353.1 ETZ07520.1 - 0.01 16.2 4.9 0.085 13.3 0.0 2.6 2 1 0 2 2 2 0 Phosphoglucose isomerase N-terminal domain DUF758 PF05527.11 ETZ07521.1 - 0.038 14.0 0.2 4.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF758) PG_isomerase_N PF18353.1 ETZ07523.1 - 0.0047 17.3 2.9 0.12 12.7 0.0 2.7 2 0 0 2 2 2 2 Phosphoglucose isomerase N-terminal domain PG_isomerase_N PF18353.1 ETZ07525.1 - 0.018 15.4 0.6 0.059 13.8 0.0 2.1 2 0 0 2 2 2 0 Phosphoglucose isomerase N-terminal domain DUF2380 PF09533.10 ETZ07525.1 - 0.05 13.2 0.3 0.086 12.5 0.3 1.3 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) GPS2_interact PF15784.5 ETZ07526.1 - 0.22 12.0 2.3 0.49 10.9 0.2 2.0 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain PG_isomerase_N PF18353.1 ETZ07527.1 - 0.005 17.2 2.5 0.14 12.5 0.0 2.7 2 0 0 2 2 2 2 Phosphoglucose isomerase N-terminal domain PG_isomerase_N PF18353.1 ETZ07529.1 - 0.0098 16.3 0.3 0.038 14.4 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucose isomerase N-terminal domain PCRF PF03462.18 ETZ07530.1 - 6e-45 153.5 0.5 1.5e-44 152.2 0.0 1.8 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 ETZ07530.1 - 1.2e-39 134.8 0.1 1.9e-39 134.2 0.1 1.3 1 0 0 1 1 1 1 RF-1 domain MIR PF02815.19 ETZ07530.1 - 0.056 13.3 0.2 0.16 11.8 0.1 1.7 1 1 1 2 2 2 0 MIR domain Vert_HS_TF PF06546.11 ETZ07530.1 - 0.37 10.4 1.3 0.46 10.1 0.2 1.7 2 0 0 2 2 2 0 Vertebrate heat shock transcription factor SecD_SecF PF02355.16 ETZ07531.1 - 8.3e-54 181.8 8.1 8.3e-54 181.8 8.1 1.5 2 0 0 2 2 2 1 Protein export membrane protein Sec_GG PF07549.14 ETZ07531.1 - 1.4e-06 27.6 0.0 3.3e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 SecD/SecF GG Motif DUF2207 PF09972.9 ETZ07531.1 - 8.8 5.0 10.2 5 5.8 2.8 2.3 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) SecD_SecF PF02355.16 ETZ07532.1 - 7.7e-16 58.0 9.6 1.4e-15 57.2 9.6 1.4 1 0 0 1 1 1 1 Protein export membrane protein MMPL PF03176.15 ETZ07532.1 - 7.3e-06 25.1 16.3 1.3e-05 24.3 16.3 1.3 1 0 0 1 1 1 1 MMPL family ACR_tran PF00873.19 ETZ07532.1 - 3.8e-05 21.6 13.0 3.8e-05 21.6 13.0 1.5 2 0 0 2 2 2 1 AcrB/AcrD/AcrF family Sec_GG PF07549.14 ETZ07532.1 - 5.1e-05 22.6 0.0 0.00011 21.5 0.0 1.6 1 0 0 1 1 1 1 SecD/SecF GG Motif Glyco_hydro_106 PF17132.4 ETZ07532.1 - 0.13 10.5 0.2 0.19 10.0 0.2 1.1 1 0 0 1 1 1 0 alpha-L-rhamnosidase Mg_chelatase PF01078.21 ETZ07533.1 - 6.2e-81 270.7 0.0 1.1e-80 269.9 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ChlI PF13541.6 ETZ07533.1 - 2.5e-35 121.0 0.0 4.3e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Mg_chelatase_C PF13335.6 ETZ07533.1 - 3.8e-20 72.3 0.3 7.4e-20 71.4 0.3 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI C-terminal MCM PF00493.23 ETZ07533.1 - 2.9e-10 39.6 0.0 1.1e-07 31.2 0.0 2.3 2 0 0 2 2 2 2 MCM P-loop domain AAA_5 PF07728.14 ETZ07533.1 - 6.5e-08 32.7 0.0 1.1e-06 28.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 ETZ07533.1 - 2.4e-05 24.1 0.0 0.00033 20.4 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 ETZ07533.1 - 2.4e-05 24.7 0.0 0.00014 22.3 0.0 2.3 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 ETZ07533.1 - 0.0005 19.6 0.1 0.029 13.9 0.0 2.7 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_30 PF13604.6 ETZ07533.1 - 0.0066 16.2 0.3 0.048 13.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ETZ07533.1 - 0.044 14.1 0.0 0.15 12.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ETZ07533.1 - 0.061 13.7 0.3 0.31 11.4 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 ETZ07533.1 - 0.094 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ETZ07533.1 - 0.12 12.9 0.0 0.28 11.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.17 ETZ07533.1 - 0.17 11.6 0.2 0.35 10.6 0.2 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_29 PF13555.6 ETZ07533.1 - 0.18 11.6 0.2 0.36 10.6 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF257 PF03192.13 ETZ07534.1 - 0.078 12.8 0.0 0.092 12.5 0.0 1.0 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 Ntox5 PF15543.6 ETZ07534.1 - 0.096 12.5 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial toxin 5 tRNA-synt_1 PF00133.22 ETZ07536.1 - 2.8e-186 620.4 2.3 8.7e-185 615.4 2.3 2.3 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 ETZ07536.1 - 9.5e-29 100.3 0.6 2.2e-28 99.1 0.6 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 ETZ07536.1 - 2.9e-25 88.8 0.1 1.1e-08 34.2 0.0 3.5 3 1 0 3 3 3 3 tRNA synthetases class I (M) Val_tRNA-synt_C PF10458.9 ETZ07536.1 - 3e-09 37.0 2.0 6.6e-09 35.9 2.0 1.6 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1_2 PF13603.6 ETZ07536.1 - 9.2e-08 31.8 0.0 0.00058 19.4 0.0 2.5 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 CdiI_2 PF18593.1 ETZ07536.1 - 0.0025 18.4 0.1 2.2 9.0 0.1 2.8 2 0 0 2 2 2 1 CdiI immunity protein tRNA-synt_1e PF01406.19 ETZ07536.1 - 0.0042 16.5 0.0 1.6 8.0 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain ADIP PF11559.8 ETZ07536.1 - 0.072 13.2 2.8 0.14 12.2 2.8 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding tRNA-synt_1b PF00579.25 ETZ07536.1 - 0.089 12.1 0.9 1.7 7.9 0.0 2.9 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) Tup_N PF08581.10 ETZ07536.1 - 0.13 12.6 2.7 0.58 10.5 2.7 2.1 1 0 0 1 1 1 0 Tup N-terminal tRNA-synt_1d PF00750.19 ETZ07536.1 - 0.14 11.1 1.7 12 4.7 0.0 2.7 3 0 0 3 3 3 0 tRNA synthetases class I (R) betaPIX_CC PF16523.5 ETZ07536.1 - 3.8 7.4 6.9 6.7 6.6 1.0 2.7 2 0 0 2 2 2 0 betaPIX coiled coil DDE_Tnp_1_assoc PF13808.6 ETZ07537.1 - 1.9e-25 88.7 0.0 5.3e-25 87.3 0.0 1.8 1 0 0 1 1 1 1 DDE_Tnp_1-associated DDE_Tnp_1 PF01609.21 ETZ07537.1 - 1.3e-16 60.9 0.9 2e-16 60.3 0.9 1.2 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_4 PF13701.6 ETZ07537.1 - 0.0054 15.0 0.0 0.46 8.7 0.0 2.2 2 0 0 2 2 2 2 Transposase DDE domain group 1 Ribosomal_L21p PF00829.21 ETZ07539.1 - 1.1e-25 89.8 0.4 1.7e-25 89.2 0.4 1.3 1 1 0 1 1 1 1 Ribosomal prokaryotic L21 protein Ribosomal_L27 PF01016.19 ETZ07540.1 - 1.7e-34 117.7 2.8 1.9e-34 117.5 2.8 1.0 1 0 0 1 1 1 1 Ribosomal L27 protein Death_2 PF14786.6 ETZ07541.1 - 0.0024 17.8 0.3 0.0073 16.2 0.2 1.8 2 0 0 2 2 2 1 Tube Death domain Arm-DNA-bind_2 PF12167.8 ETZ07541.1 - 0.15 12.0 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 Arm DNA-binding domain DUF1827 PF08860.10 ETZ07541.1 - 0.63 10.3 5.0 0.3 11.4 1.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1827) TPR_22 PF18833.1 ETZ07541.1 - 0.7 10.1 5.0 8.5 6.6 0.3 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DegT_DnrJ_EryC1 PF01041.17 ETZ07542.1 - 4.7e-103 345.3 0.0 5.3e-103 345.1 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 ETZ07542.1 - 5.4e-09 35.7 0.0 7.7e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 ETZ07542.1 - 0.005 15.8 0.0 0.0082 15.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 ETZ07542.1 - 0.0054 16.1 0.0 0.01 15.1 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 ETZ07542.1 - 0.045 12.5 0.0 0.1 11.3 0.0 1.5 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Competence PF03772.16 ETZ07543.1 - 7.9e-47 159.8 32.7 7.9e-47 159.8 32.7 2.4 2 1 1 3 3 3 1 Competence protein DUF4131 PF13567.6 ETZ07543.1 - 7.2e-05 22.5 0.7 7.2e-05 22.5 0.7 4.3 3 2 0 3 3 3 1 Domain of unknown function (DUF4131) CPP1-like PF11833.8 ETZ07543.1 - 0.033 13.9 0.0 0.033 13.9 0.0 2.3 3 0 0 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like tRNA_anti_2 PF13742.6 ETZ07543.1 - 0.041 14.1 0.0 0.99 9.6 0.0 2.5 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain DUF4096 PF13340.6 ETZ07544.1 - 1.3e-26 92.6 3.6 2.1e-26 91.9 3.6 1.3 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DHDPS PF00701.22 ETZ07545.1 - 6e-45 153.2 0.0 7.9e-45 152.8 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Imm17 PF15562.6 ETZ07546.1 - 0.17 11.8 28.0 0.98 9.3 0.1 11.5 16 0 0 16 16 16 0 Immunity protein 17 YaaC PF14175.6 ETZ07546.1 - 0.21 10.8 14.2 1.3 8.2 0.2 7.1 8 0 0 8 8 8 0 YaaC-like Protein Rotamase PF00639.21 ETZ07546.1 - 0.25 12.3 63.3 12 6.9 0.1 18.0 20 0 0 20 20 20 0 PPIC-type PPIASE domain PIP49_C PF12260.8 ETZ07546.1 - 9.4 5.8 12.2 1.5 8.4 0.4 4.1 4 0 0 4 4 4 0 Protein-kinase domain of FAM69 DDE_3 PF13358.6 ETZ07547.1 - 1.4e-06 28.1 0.0 1.4e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HSP70 PF00012.20 ETZ07548.1 - 6.6e-103 344.9 0.0 1.3e-99 334.1 0.0 2.2 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 ETZ07548.1 - 2.7e-12 46.1 0.0 3e-11 42.7 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DnaJ PF00226.31 ETZ07549.1 - 5.6e-08 32.8 0.1 1.5e-07 31.4 0.0 1.7 2 0 0 2 2 2 1 DnaJ domain Transgly PF00912.22 ETZ07550.1 - 1.5e-55 187.4 0.0 3e-55 186.5 0.0 1.5 1 0 0 1 1 1 1 Transglycosylase Transpeptidase PF00905.22 ETZ07550.1 - 5e-28 98.2 0.0 1.2e-27 96.9 0.0 1.6 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain CtsR_C PF17727.1 ETZ07550.1 - 0.0021 18.1 0.4 0.01 15.9 0.0 2.4 3 0 0 3 3 3 1 CtsR C-terminal dimerization domain tRNA_synt_2f PF02092.17 ETZ07551.1 - 7.5e-129 431.1 0.0 9e-129 430.8 0.0 1.1 1 0 0 1 1 1 1 Glycyl-tRNA synthetase beta subunit CSD PF00313.22 ETZ07552.1 - 1e-22 79.7 0.0 1.2e-22 79.6 0.0 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 ETZ07552.1 - 2.1e-05 24.1 0.2 2.7e-05 23.8 0.2 1.4 1 1 0 1 1 1 1 Ribonuclease B OB domain TruB_N PF01509.18 ETZ07553.1 - 5.3e-43 146.9 0.0 7e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 ETZ07553.1 - 7.1e-07 29.3 0.0 1.1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain Ribosomal_S15 PF00312.22 ETZ07554.1 - 4e-28 97.5 0.5 4.7e-28 97.2 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S15 CARD_2 PF16739.5 ETZ07554.1 - 0.096 12.7 0.0 0.13 12.3 0.0 1.4 1 1 0 1 1 1 0 Caspase recruitment domain RNase_PH PF01138.21 ETZ07555.1 - 7.9e-38 129.9 0.0 8.4e-19 68.4 0.0 2.3 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 S1 PF00575.23 ETZ07555.1 - 1.5e-13 50.8 0.2 3.3e-13 49.8 0.2 1.5 1 0 0 1 1 1 1 S1 RNA binding domain KH_1 PF00013.29 ETZ07555.1 - 2.1e-07 30.7 0.1 5.5e-07 29.3 0.1 1.7 1 0 0 1 1 1 1 KH domain RNase_PH_C PF03725.15 ETZ07555.1 - 0.00076 19.5 0.3 0.014 15.4 0.1 2.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 KH_2 PF07650.17 ETZ07555.1 - 0.018 14.9 0.0 0.048 13.5 0.0 1.8 1 1 0 1 1 1 0 KH domain DUF3016 PF11454.8 ETZ07555.1 - 0.08 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) PNPase PF03726.14 ETZ07555.1 - 0.12 12.9 0.1 0.37 11.3 0.0 1.9 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain RNase_E_G PF10150.9 ETZ07556.1 - 2.4e-89 299.3 0.9 2.4e-89 299.3 0.9 2.4 2 0 0 2 2 2 1 Ribonuclease E/G family S1 PF00575.23 ETZ07556.1 - 0.003 17.9 0.1 0.17 12.3 0.0 3.2 2 0 0 2 2 2 1 S1 RNA binding domain BacA PF02673.18 ETZ07558.1 - 1.4e-42 146.2 16.8 1.6e-42 146.0 16.8 1.0 1 0 0 1 1 1 1 Bacitracin resistance protein BacA BPL_LplA_LipB PF03099.19 ETZ07559.1 - 0.00024 21.0 0.0 0.00037 20.4 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Ank_2 PF12796.7 ETZ07561.1 - 0.0022 18.6 9.1 0.12 13.0 1.5 4.2 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) Paramyx_P_V_C PF03210.13 ETZ07561.1 - 0.007 16.2 0.2 1.1 9.0 0.0 2.9 2 0 0 2 2 2 1 Paramyxovirus P/V phosphoprotein C-terminal CBP PF12192.8 ETZ07561.1 - 0.048 13.9 2.6 41 4.5 0.1 4.0 4 0 0 4 4 4 0 Fungal calcium binding protein HTH_9 PF08221.11 ETZ07561.1 - 0.1 12.7 0.3 24 5.1 0.0 4.3 4 1 0 4 4 4 0 RNA polymerase III subunit RPC82 helix-turn-helix domain AID PF18767.1 ETZ07561.1 - 0.16 12.0 3.7 29 4.8 0.1 3.7 2 1 1 3 3 3 0 Activation induced deaminase SPG48 PF14764.6 ETZ07561.1 - 0.2 12.1 5.5 0.51 10.8 0.3 3.7 1 1 3 4 4 4 0 AP-5 complex subunit, vesicle trafficking ESCRT-II PF05871.12 ETZ07561.1 - 2.8 8.2 7.1 2.5 8.4 0.4 3.5 4 0 0 4 4 4 0 ESCRT-II complex subunit DUF3873 PF12989.7 ETZ07562.1 - 0.0094 16.3 0.1 0.021 15.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function, B. Theta Gene description (DUF3873) NP1-WLL PF11733.8 ETZ07562.1 - 0.13 12.0 0.7 0.2 11.4 0.1 1.5 2 0 0 2 2 2 0 Non-capsid protein NP1 Transcrip_reg PF01709.20 ETZ07563.1 - 1.5e-70 237.3 0.0 1.7e-70 237.2 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator DPBB_1 PF03330.18 ETZ07564.1 - 2.3e-19 69.4 0.2 5.5e-19 68.2 0.0 1.7 2 0 0 2 2 2 1 Lytic transglycolase Peptidase_S11 PF00768.20 ETZ07565.1 - 1.6e-51 175.0 0.0 2.1e-51 174.7 0.0 1.1 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase PBP5_C PF07943.13 ETZ07565.1 - 4.3e-12 46.1 0.1 7.5e-12 45.3 0.1 1.4 1 0 0 1 1 1 1 Penicillin-binding protein 5, C-terminal domain Beta-lactamase2 PF13354.6 ETZ07565.1 - 1.2e-07 31.6 0.0 1.5e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase enzyme family DUF1381 PF07129.11 ETZ07565.1 - 0.11 12.3 0.1 4.2 7.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1381) Peptidase_S13 PF02113.15 ETZ07565.1 - 0.22 10.2 0.0 0.35 9.5 0.0 1.2 1 0 0 1 1 1 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family Thymidylate_kin PF02223.17 ETZ07566.1 - 2.4e-37 128.4 0.0 2.6e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 ETZ07566.1 - 0.0015 18.8 0.0 0.0018 18.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain RuvA_N PF01330.21 ETZ07567.1 - 2e-14 53.4 0.5 2.6e-13 49.9 0.5 2.4 3 0 0 3 3 3 1 RuvA N terminal domain HHH_5 PF14520.6 ETZ07567.1 - 1e-12 48.5 0.3 2.1e-12 47.4 0.3 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain RuvA_C PF07499.13 ETZ07567.1 - 6.8e-07 29.6 0.0 1.4e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 RuvA, C-terminal domain HHH PF00633.23 ETZ07567.1 - 8e-07 28.6 0.1 0.0043 16.9 0.0 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_3 PF12836.7 ETZ07567.1 - 0.00028 21.1 0.1 0.43 10.9 0.0 2.4 2 0 0 2 2 2 2 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 ETZ07567.1 - 0.0003 21.3 0.1 0.059 14.0 0.0 2.3 1 1 1 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 ETZ07567.1 - 0.00051 20.1 0.0 0.43 10.7 0.0 2.4 1 1 1 2 2 2 2 Helix-hairpin-helix motif HHH_8 PF14716.6 ETZ07567.1 - 0.00061 20.1 0.3 0.59 10.5 0.1 2.5 1 1 1 2 2 2 2 Helix-hairpin-helix domain Transposase_20 PF02371.16 ETZ07567.1 - 0.0042 17.4 0.0 3.8 7.9 0.0 2.6 2 0 0 2 2 2 2 Transposase IS116/IS110/IS902 family Cdd1 PF11731.8 ETZ07567.1 - 0.0087 16.3 0.0 1.8 8.9 0.0 2.4 2 0 0 2 2 2 1 Pathogenicity locus IMS_HHH PF11798.8 ETZ07567.1 - 0.022 15.1 0.0 13 6.3 0.0 2.5 2 0 0 2 2 2 0 IMS family HHH motif tRNA_bind_3 PF17176.4 ETZ07567.1 - 0.056 13.7 0.1 0.11 12.9 0.1 1.5 1 0 0 1 1 1 0 tRNA-binding domain DUF3701 PF12482.8 ETZ07567.1 - 0.057 13.5 0.0 1.4 9.1 0.0 2.5 2 1 1 3 3 3 0 Phage integrase protein Utp12 PF04003.12 ETZ07567.1 - 0.084 13.2 0.1 0.48 10.8 0.0 2.1 2 0 0 2 2 2 0 Dip2/Utp12 Family Polysacc_deac_1 PF01522.21 ETZ07569.1 - 8.6e-28 96.7 0.0 2.6e-27 95.2 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF2334 PF10096.9 ETZ07569.1 - 0.00019 21.1 0.2 0.011 15.4 0.1 2.4 2 1 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2334) DUF4274 PF14096.6 ETZ07569.1 - 0.14 12.2 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4274) DUF2380 PF09533.10 ETZ07571.1 - 0.047 13.3 0.4 0.062 12.9 0.4 1.2 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) PG_isomerase_N PF18353.1 ETZ07573.1 - 0.0048 17.3 3.2 0.079 13.4 0.0 2.7 2 0 0 2 2 2 1 Phosphoglucose isomerase N-terminal domain Ribosomal_L29 PF00831.23 ETZ07573.1 - 3.5 7.7 5.1 0.53 10.3 0.1 2.2 2 0 0 2 2 2 0 Ribosomal L29 protein MarC PF01914.17 ETZ07575.1 - 9.5e-34 116.6 12.3 1.1e-33 116.4 12.3 1.0 1 0 0 1 1 1 1 MarC family integral membrane protein DapB_C PF05173.14 ETZ07576.1 - 3.2e-22 78.8 0.0 5e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus DapB_N PF01113.20 ETZ07576.1 - 1.8e-05 24.8 0.0 8.7e-05 22.6 0.0 2.1 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 ETZ07576.1 - 0.11 11.5 0.2 0.17 10.8 0.2 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Abhydrolase_1 PF00561.20 ETZ07577.1 - 0.003 17.2 0.0 0.0072 16.0 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ndr PF03096.14 ETZ07577.1 - 0.047 12.4 0.0 0.069 11.8 0.0 1.3 1 0 0 1 1 1 0 Ndr family ABC_tran PF00005.27 ETZ07578.1 - 7.1e-29 101.1 0.0 1.1e-28 100.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ETZ07578.1 - 2e-11 44.3 0.4 1.1e-06 28.7 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ETZ07578.1 - 3.7e-06 26.5 0.2 0.00059 19.3 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ETZ07578.1 - 0.00011 22.7 0.0 0.00014 22.3 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 ETZ07578.1 - 0.00025 21.6 0.6 0.022 15.3 0.6 2.3 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ETZ07578.1 - 0.0013 18.6 0.1 0.003 17.5 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 ETZ07578.1 - 0.0023 17.6 0.6 0.0085 15.8 0.6 1.9 1 1 1 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 ETZ07578.1 - 0.013 16.0 1.2 0.027 15.0 0.1 1.8 1 1 0 2 2 2 0 AAA domain CPT PF07931.12 ETZ07578.1 - 0.044 13.6 0.1 0.083 12.7 0.1 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein MeaB PF03308.16 ETZ07578.1 - 0.045 12.7 0.0 0.071 12.1 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 ETZ07578.1 - 0.045 13.0 0.0 0.081 12.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 ETZ07578.1 - 0.057 12.6 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain G-alpha PF00503.20 ETZ07578.1 - 0.057 12.6 0.1 0.11 11.7 0.1 1.4 1 1 0 1 1 1 0 G-protein alpha subunit PhoH PF02562.16 ETZ07578.1 - 0.071 12.6 0.0 0.15 11.5 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein PRK PF00485.18 ETZ07578.1 - 0.099 12.4 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.6 ETZ07578.1 - 0.16 12.3 0.7 0.62 10.3 0.7 2.0 1 1 0 1 1 1 0 AAA domain BPD_transp_1 PF00528.22 ETZ07579.1 - 2.8e-18 66.3 2.9 3.9e-18 65.9 2.9 1.2 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component SBP_bac_3 PF00497.20 ETZ07580.1 - 1.5e-44 152.1 0.0 1.7e-44 151.9 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 ETZ07580.1 - 5.6e-09 36.2 0.1 4.7e-07 30.0 0.1 2.3 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site DUF1406 PF07190.11 ETZ07580.1 - 0.018 15.0 0.1 0.04 13.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1406) tRNA-synt_2d PF01409.20 ETZ07581.1 - 4.6e-92 307.9 0.0 6.1e-92 307.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) Phe_tRNA-synt_N PF02912.18 ETZ07581.1 - 1.1e-13 50.9 4.8 1.8e-13 50.2 4.8 1.3 1 0 0 1 1 1 1 Aminoacyl tRNA synthetase class II, N-terminal domain BCDHK_Adom3 PF10436.9 ETZ07581.1 - 0.0089 15.9 2.4 2.1 8.2 0.1 2.9 2 1 0 2 2 2 2 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase ACR_tran PF00873.19 ETZ07582.1 - 1.2e-245 817.8 2.9 1.5e-245 817.5 2.9 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 ETZ07582.1 - 2.5e-17 62.8 27.1 3.6e-12 45.9 9.2 2.6 3 0 0 3 3 3 2 MMPL family SecD_SecF PF02355.16 ETZ07582.1 - 0.011 15.1 25.8 0.067 12.6 12.6 2.4 2 0 0 2 2 2 0 Protein export membrane protein 4HB_MCP_1 PF12729.7 ETZ07582.1 - 0.11 12.1 3.9 0.11 12.0 0.3 2.6 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction HlyD_3 PF13437.6 ETZ07583.1 - 2.2e-09 38.0 0.8 4e-08 33.9 0.2 2.6 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_D23 PF16576.5 ETZ07583.1 - 5.4e-09 35.6 0.8 8.4e-09 35.0 0.8 1.3 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_2 PF12700.7 ETZ07583.1 - 2e-05 23.5 0.7 0.0011 17.8 0.0 2.3 2 0 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 ETZ07583.1 - 0.00067 19.4 2.8 0.002 17.9 0.0 3.2 4 0 0 4 4 4 1 Biotin-lipoyl like Alkyl_sulf_dimr PF14863.6 ETZ07583.1 - 0.012 16.1 0.1 0.18 12.2 0.0 2.2 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation Biotin_lipoyl PF00364.22 ETZ07583.1 - 0.075 12.9 5.9 1.9 8.4 0.0 4.3 3 1 2 5 5 5 0 Biotin-requiring enzyme MlaE PF02405.16 ETZ07585.1 - 4.4e-59 199.7 14.2 5.8e-59 199.3 14.2 1.1 1 0 0 1 1 1 1 Permease MlaE BON PF04972.17 ETZ07586.1 - 3.7e-13 49.6 0.1 3.8e-09 36.7 0.6 2.1 2 0 0 2 2 2 2 BON domain S-AdoMet_synt_N PF00438.20 ETZ07586.1 - 0.13 12.9 0.1 0.77 10.5 0.0 1.9 2 0 0 2 2 2 0 S-adenosylmethionine synthetase, N-terminal domain ABC_membrane PF00664.23 ETZ07587.1 - 3.1e-36 125.5 12.1 4.6e-36 124.9 12.1 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 ETZ07587.1 - 2.6e-31 108.9 0.0 5.5e-31 107.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ETZ07587.1 - 5.4e-09 35.8 0.1 1.6e-05 24.4 0.1 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ETZ07587.1 - 3.1e-05 24.6 0.3 0.00058 20.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 ETZ07587.1 - 5.8e-05 22.1 0.0 0.00014 20.9 0.0 1.6 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_22 PF13401.6 ETZ07587.1 - 9.9e-05 22.6 0.5 0.27 11.5 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.6 ETZ07587.1 - 0.00013 21.9 0.9 0.026 14.4 0.2 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 ETZ07587.1 - 0.0029 16.7 0.0 0.0052 15.9 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 ETZ07587.1 - 0.0096 15.7 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF87 PF01935.17 ETZ07587.1 - 0.0096 16.0 0.0 0.073 13.2 0.0 2.2 2 0 0 2 2 2 1 Helicase HerA, central domain ResIII PF04851.15 ETZ07587.1 - 0.011 15.7 0.2 0.043 13.8 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DEAD PF00270.29 ETZ07587.1 - 0.026 14.3 0.0 0.16 11.8 0.0 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase TFIIB PF00382.19 ETZ07587.1 - 0.039 14.0 0.0 0.088 12.9 0.0 1.5 1 0 0 1 1 1 0 Transcription factor TFIIB repeat AAA_16 PF13191.6 ETZ07587.1 - 0.11 12.9 0.2 0.49 10.8 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 ETZ07587.1 - 0.22 11.3 0.6 0.47 10.1 0.2 1.9 2 1 0 2 2 2 0 AAA domain DUF3953 PF13129.6 ETZ07587.1 - 0.26 11.1 0.0 0.26 11.1 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3953) OMP_b-brl PF13505.6 ETZ07588.1 - 1.8e-10 41.2 4.4 1.3e-09 38.4 4.4 2.2 1 1 0 1 1 1 1 Outer membrane protein beta-barrel domain OmpA_membrane PF01389.17 ETZ07588.1 - 2.9e-05 23.9 0.0 4.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 OmpA-like transmembrane domain Pom PF17251.2 ETZ07588.1 - 0.00081 18.8 0.2 0.001 18.5 0.2 1.2 1 0 0 1 1 1 1 Protochlamydia outer membrane protein DUF3373 PF11853.8 ETZ07588.1 - 0.045 12.9 1.5 7.6 5.5 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3373) MtrB_PioB PF11854.8 ETZ07588.1 - 0.047 12.1 0.1 0.066 11.5 0.1 1.1 1 0 0 1 1 1 0 Putative outer membrane beta-barrel porin, MtrB/PioB OMP_b-brl PF13505.6 ETZ07589.1 - 8.9e-07 29.2 3.4 7.7e-06 26.2 3.4 2.4 1 1 0 1 1 1 1 Outer membrane protein beta-barrel domain OmpA_membrane PF01389.17 ETZ07589.1 - 0.00013 21.8 0.0 0.0002 21.2 0.0 1.3 1 0 0 1 1 1 1 OmpA-like transmembrane domain MtrB_PioB PF11854.8 ETZ07589.1 - 0.02 13.2 0.0 0.032 12.6 0.0 1.2 1 0 0 1 1 1 0 Putative outer membrane beta-barrel porin, MtrB/PioB rve PF00665.26 ETZ07591.1 - 2e-05 24.8 0.0 2.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain O-ag_pol_Wzy PF14296.6 ETZ07592.1 - 0.033 12.8 3.1 0.035 12.8 3.1 1.0 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy IF3_N PF05198.16 ETZ07594.1 - 4.3e-28 97.4 2.0 8.7e-28 96.4 0.0 2.2 3 0 0 3 3 3 1 Translation initiation factor IF-3, N-terminal domain IF3_C PF00707.22 ETZ07594.1 - 6.4e-19 67.7 0.3 1.2e-18 66.9 0.3 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain ParA PF10609.9 ETZ07594.1 - 0.044 13.2 0.2 0.055 12.9 0.2 1.1 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase tRNA-synt_2b PF00587.25 ETZ07595.1 - 2.1e-39 135.3 0.0 3.9e-39 134.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_SAD PF07973.14 ETZ07595.1 - 1.7e-12 47.2 0.0 5.4e-12 45.6 0.0 1.9 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain HGTP_anticodon PF03129.20 ETZ07595.1 - 5.5e-12 45.7 0.1 1.1e-11 44.7 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain O_anti_polymase PF01901.16 ETZ07597.1 - 0.084 12.1 0.1 0.4 9.9 0.1 1.8 1 1 0 1 1 1 0 Putative O-antigen polymerase Epiglycanin_C PF14654.6 ETZ07597.1 - 0.098 12.7 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region tRNA-synt_2e PF02091.15 ETZ07598.1 - 8e-113 376.3 0.0 9.2e-113 376.1 0.0 1.0 1 0 0 1 1 1 1 Glycyl-tRNA synthetase alpha subunit PolyA_pol PF01743.20 ETZ07599.1 - 4.5e-20 72.3 0.0 7.2e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 ETZ07599.1 - 7.7e-09 35.2 0.1 2.2e-08 33.7 0.0 1.8 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A MreB_Mbl PF06723.13 ETZ07600.1 - 1.9e-131 437.7 3.3 2.3e-131 437.5 3.3 1.0 1 0 0 1 1 1 1 MreB/Mbl protein HSP70 PF00012.20 ETZ07600.1 - 5.3e-14 51.3 2.6 5.8e-13 47.9 0.2 2.7 2 1 0 2 2 2 1 Hsp70 protein Actin PF00022.19 ETZ07600.1 - 1.5e-11 43.6 0.0 1.2e-08 34.0 0.0 2.1 1 1 1 2 2 2 2 Actin PilM_2 PF11104.8 ETZ07600.1 - 2.1e-07 30.3 0.0 0.013 14.5 0.0 3.0 2 1 1 3 3 3 2 Type IV pilus assembly protein PilM; FtsA PF14450.6 ETZ07600.1 - 3e-07 30.8 0.8 1.2e-06 28.9 0.1 2.1 2 1 0 2 2 2 1 Cell division protein FtsA EutA PF06277.11 ETZ07600.1 - 0.00014 20.9 0.3 0.0016 17.4 0.1 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation protein EutA Ppx-GppA PF02541.16 ETZ07600.1 - 0.0013 18.2 0.1 0.0056 16.1 0.1 2.0 3 0 0 3 3 3 1 Ppx/GppA phosphatase family DDR PF08841.10 ETZ07600.1 - 0.0042 16.1 0.9 0.012 14.7 0.4 1.9 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain StbA PF06406.11 ETZ07600.1 - 0.1 11.8 0.4 0.4 9.9 0.3 2.0 1 1 0 1 1 1 0 StbA protein CTP_synth_N PF06418.14 ETZ07601.1 - 5.2e-100 334.1 0.0 6.8e-100 333.7 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 ETZ07601.1 - 3e-52 177.1 0.1 4.9e-52 176.5 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ETZ07601.1 - 4.6e-10 39.6 0.2 1.1e-08 35.1 0.2 2.8 2 1 0 2 2 2 1 Peptidase C26 DJ-1_PfpI PF01965.24 ETZ07601.1 - 0.0044 16.8 0.0 0.14 12.0 0.0 2.3 2 0 0 2 2 2 1 DJ-1/PfpI family CbiA PF01656.23 ETZ07601.1 - 0.0059 16.7 0.0 0.0096 16.0 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SNO PF01174.19 ETZ07601.1 - 0.013 15.4 0.1 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 SNO glutamine amidotransferase family GATase_3 PF07685.14 ETZ07601.1 - 0.014 15.0 0.1 0.034 13.7 0.1 1.7 1 1 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Proton_antipo_N PF00662.20 ETZ07602.1 - 3e-07 30.4 6.7 8.2e-07 29.0 6.7 1.8 1 0 0 1 1 1 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Proton_antipo_M PF00361.20 ETZ07603.1 - 1.8e-34 119.3 15.3 1.8e-34 119.3 15.3 2.0 1 1 2 3 3 3 1 Proton-conducting membrane transporter DUF2309 PF10070.9 ETZ07604.1 - 1.8e-201 671.4 0.0 3.9e-192 640.5 0.0 2.0 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2309) SLT PF01464.20 ETZ07605.1 - 7.1e-12 45.0 0.0 1.4e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Transglycosylase SLT domain TPR_2 PF07719.17 ETZ07605.1 - 0.0076 16.3 10.5 0.29 11.3 0.7 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 ETZ07605.1 - 0.098 12.5 5.2 0.92 9.4 1.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 ETZ07605.1 - 0.15 12.7 0.0 5 7.9 0.0 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.12 ETZ07605.1 - 0.31 11.8 1.9 25 5.7 0.2 3.0 2 1 0 2 2 2 0 Sel1 repeat TonB_2 PF13103.6 ETZ07606.1 - 0.0051 17.0 0.1 0.096 12.9 0.0 2.3 2 0 0 2 2 2 1 TonB C terminal PAT1 PF09770.9 ETZ07606.1 - 0.038 12.3 5.5 0.043 12.1 5.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Rgp1 PF08737.10 ETZ07606.1 - 0.098 11.8 10.9 0.13 11.4 10.9 1.1 1 0 0 1 1 1 0 Rgp1 MAT1 PF06391.13 ETZ07606.1 - 0.12 12.2 11.5 0.15 11.8 11.5 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 SLC12 PF03522.15 ETZ07606.1 - 0.13 11.2 6.7 0.16 11.0 6.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 V_ATPase_I PF01496.19 ETZ07606.1 - 0.72 7.7 5.0 0.86 7.4 5.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CLN3 PF02487.17 ETZ07606.1 - 0.84 8.6 2.0 1.1 8.3 2.0 1.1 1 0 0 1 1 1 0 CLN3 protein Zip PF02535.22 ETZ07606.1 - 0.86 8.8 4.3 1.1 8.4 4.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 ETZ07606.1 - 1.9 7.2 10.3 2.3 6.9 10.3 1.2 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 ETZ07606.1 - 4.1 7.4 7.7 5.6 7.0 7.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Membralin PF09746.9 ETZ07606.1 - 7.6 5.5 8.9 11 5.0 8.9 1.1 1 0 0 1 1 1 0 Tumour-associated protein ExbD PF02472.16 ETZ07607.1 - 1.1e-24 87.1 0.1 1.3e-24 86.8 0.1 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR Cation_ATPase_C PF00689.21 ETZ07607.1 - 0.067 12.9 0.1 0.42 10.3 0.0 1.9 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus DUF2149 PF09919.9 ETZ07607.1 - 0.1 12.9 0.5 0.31 11.3 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) MotA_ExbB PF01618.16 ETZ07608.1 - 8e-35 119.4 0.3 1.8e-34 118.2 0.3 1.6 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family DUF2207 PF09972.9 ETZ07608.1 - 0.02 13.7 1.2 0.033 13.0 0.2 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) TNV_CP PF03898.13 ETZ07608.1 - 0.18 11.1 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Satellite tobacco necrosis virus coat protein LapA_dom PF06305.11 ETZ07608.1 - 0.3 10.9 3.4 0.41 10.5 1.1 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Csm1_N PF18504.1 ETZ07609.1 - 0.0054 17.0 3.3 0.0075 16.6 3.3 1.2 1 0 0 1 1 1 1 Csm1 N-terminal domain ATHILA PF03078.15 ETZ07609.1 - 0.021 13.7 2.7 0.025 13.4 2.7 1.0 1 0 0 1 1 1 0 ATHILA ORF-1 family Forkhead PF00250.18 ETZ07609.1 - 0.021 15.0 0.3 0.029 14.6 0.3 1.2 1 0 0 1 1 1 0 Forkhead domain zf-CRD PF17979.1 ETZ07609.1 - 0.041 14.0 0.4 0.045 13.9 0.4 1.1 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions Rx_N PF18052.1 ETZ07609.1 - 0.062 13.6 0.6 0.078 13.3 0.6 1.2 1 0 0 1 1 1 0 Rx N-terminal domain SseC PF04888.12 ETZ07609.1 - 1.7 8.2 7.5 2.3 7.8 7.5 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family EPSP_synthase PF00275.20 ETZ07610.1 - 1.8e-82 277.3 0.0 2e-82 277.1 0.0 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) GrpE PF01025.19 ETZ07611.1 - 0.00084 19.0 1.3 0.00084 19.0 1.3 2.1 2 0 0 2 2 2 1 GrpE GlutR_dimer PF00745.20 ETZ07611.1 - 0.047 14.1 2.8 0.31 11.5 0.4 2.5 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain TFIIF_beta PF02270.15 ETZ07611.1 - 0.049 13.8 0.2 0.36 11.0 0.1 2.3 2 0 0 2 2 2 0 TFIIF, beta subunit HTH domain PIN_3 PF13470.6 ETZ07611.1 - 0.089 13.6 0.0 0.14 12.9 0.0 1.4 1 0 0 1 1 1 0 PIN domain Nop PF01798.18 ETZ07611.1 - 3.9 6.9 9.0 1.2 8.5 2.0 2.3 1 1 1 2 2 2 0 snoRNA binding domain, fibrillarin YchF-GTPase_C PF06071.13 ETZ07612.1 - 6.9e-38 128.7 0.1 1.9e-37 127.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 ETZ07612.1 - 3.1e-23 82.0 0.0 5.5e-23 81.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ETZ07612.1 - 2.2e-08 33.8 0.0 1.6e-07 31.0 0.0 2.4 2 1 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 ETZ07612.1 - 0.11 12.0 0.0 0.41 10.1 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family Dynamin_N PF00350.23 ETZ07612.1 - 0.15 12.1 0.2 7.4 6.6 0.0 2.4 2 1 0 3 3 3 0 Dynamin family Ribosomal_L19 PF01245.20 ETZ07613.1 - 2.8e-38 130.3 0.4 3e-38 130.1 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L19 TAL_FSA PF00923.19 ETZ07615.1 - 2.6e-44 151.7 0.1 3.9e-44 151.1 0.1 1.2 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase DUF745 PF05335.13 ETZ07615.1 - 0.023 14.4 0.1 0.033 13.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF1485 PF07364.12 ETZ07615.1 - 0.038 13.3 0.0 0.21 10.8 0.0 1.8 2 0 0 2 2 2 0 Metallopeptidase family M81 tRNA-synt_2 PF00152.20 ETZ07616.1 - 1.1e-94 317.1 0.0 1.3e-94 316.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ETZ07616.1 - 3.2e-13 49.5 0.0 6.8e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain GAD PF02938.14 ETZ07616.1 - 1.3e-12 47.8 0.0 2.8e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 GAD domain tRNA-synt_2d PF01409.20 ETZ07616.1 - 0.036 13.5 0.0 2.9 7.3 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.25 ETZ07616.1 - 0.18 11.8 0.0 0.73 9.8 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) ATP-synt_DE_N PF02823.16 ETZ07616.1 - 0.18 11.7 0.1 0.42 10.6 0.1 1.5 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DDE_3 PF13358.6 ETZ07617.1 - 2.2e-16 60.0 0.0 2.2e-16 59.9 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease YqhG PF11079.8 ETZ07617.1 - 0.046 12.7 0.0 0.051 12.5 0.0 1.0 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function SIMPL PF04402.14 ETZ07618.1 - 2.4e-12 47.7 0.0 3e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Cellulose_synt PF03552.14 ETZ07618.1 - 0.029 12.9 0.2 0.041 12.4 0.2 1.2 1 0 0 1 1 1 0 Cellulose synthase SIMPL PF04402.14 ETZ07619.1 - 7.7e-14 52.6 0.0 9.3e-14 52.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Methyltransf_4 PF02390.17 ETZ07620.1 - 1.3e-37 128.9 0.0 1.6e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.12 ETZ07620.1 - 0.11 13.2 0.0 0.49 11.1 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain ATP-synt_A PF00119.20 ETZ07621.1 - 2.4e-49 168.2 28.5 2.9e-49 167.9 28.5 1.0 1 0 0 1 1 1 1 ATP synthase A chain DUF5079 PF16882.5 ETZ07621.1 - 4.1 7.2 14.7 0.41 10.5 8.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5079) rve PF00665.26 ETZ07623.1 - 0.025 14.7 0.0 0.039 14.1 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain LRR_3 PF07725.12 ETZ07623.1 - 0.76 9.7 4.7 11 6.0 0.3 3.1 4 0 0 4 4 4 0 Leucine Rich Repeat Imm25 PF15564.6 ETZ07625.1 - 0.025 14.5 0.4 0.028 14.3 0.4 1.1 1 0 0 1 1 1 0 Immunity protein 25 UvrA_inter PF17760.1 ETZ07627.1 - 2.6e-31 107.9 0.1 7.1e-31 106.5 0.1 1.8 1 0 0 1 1 1 1 UvrA interaction domain ABC_tran PF00005.27 ETZ07627.1 - 3.2e-22 79.5 1.2 0.00012 22.6 0.0 4.5 4 0 0 4 4 4 4 ABC transporter SMC_N PF02463.19 ETZ07627.1 - 7.1e-11 42.0 0.0 0.13 11.7 0.0 4.1 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ETZ07627.1 - 1.6e-07 31.9 0.0 0.012 16.0 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 ETZ07627.1 - 2.4e-06 27.2 1.4 0.019 14.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain ATPase PF06745.13 ETZ07627.1 - 0.00011 21.6 0.1 0.24 10.7 0.0 2.5 2 0 0 2 2 2 2 KaiC RsgA_GTPase PF03193.16 ETZ07627.1 - 0.00042 20.2 0.3 0.11 12.4 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_15 PF13175.6 ETZ07627.1 - 0.00066 19.5 0.0 3.9 7.1 0.0 3.4 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 ETZ07627.1 - 0.0008 19.7 0.5 0.25 11.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 ETZ07627.1 - 0.0008 20.0 1.3 0.028 14.9 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ETZ07627.1 - 0.0011 19.2 0.0 3 8.0 0.0 3.4 4 0 0 4 4 3 1 AAA domain AAA_18 PF13238.6 ETZ07627.1 - 0.0011 19.6 0.2 2.1 8.9 0.0 3.0 3 0 0 3 3 2 1 AAA domain RNA12 PF10443.9 ETZ07627.1 - 0.0013 17.5 0.1 0.47 9.1 0.0 2.2 2 0 0 2 2 2 2 RNA12 protein AAA_25 PF13481.6 ETZ07627.1 - 0.0014 18.2 0.0 0.13 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain DnaJ_CXXCXGXG PF00684.19 ETZ07627.1 - 0.0027 18.0 9.5 0.035 14.5 1.8 2.8 2 0 0 2 2 2 1 DnaJ central domain AAA_21 PF13304.6 ETZ07627.1 - 0.006 16.4 7.2 2.1 8.1 0.0 4.0 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system PRK PF00485.18 ETZ07627.1 - 0.0079 15.9 0.0 0.94 9.2 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family NACHT PF05729.12 ETZ07627.1 - 0.012 15.6 0.2 1.2 9.0 0.0 2.8 3 0 0 3 3 2 0 NACHT domain AAA_14 PF13173.6 ETZ07627.1 - 0.016 15.2 0.4 3.4 7.7 0.0 3.2 4 0 0 4 4 3 0 AAA domain DUF2075 PF09848.9 ETZ07627.1 - 0.019 14.2 0.1 1.7 7.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RecA PF00154.21 ETZ07627.1 - 0.02 14.4 0.0 0.69 9.3 0.0 2.3 2 0 0 2 2 2 0 recA bacterial DNA recombination protein AAA_7 PF12775.7 ETZ07627.1 - 0.024 14.1 0.1 1.6 8.2 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 ETZ07627.1 - 0.025 14.2 0.2 8.4 5.9 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain APS_kinase PF01583.20 ETZ07627.1 - 0.047 13.6 0.1 5.1 7.0 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase RNA_helicase PF00910.22 ETZ07627.1 - 0.056 13.8 0.1 4.1 7.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase PhoH PF02562.16 ETZ07627.1 - 0.058 12.8 0.0 0.69 9.3 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activat PF00158.26 ETZ07627.1 - 0.068 12.9 0.0 0.38 10.4 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 ETZ07627.1 - 0.07 12.8 3.4 3.8 7.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain Cytidylate_kin PF02224.18 ETZ07627.1 - 0.072 12.8 0.1 0.42 10.3 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase Rad17 PF03215.15 ETZ07627.1 - 0.097 12.6 0.1 0.61 10.0 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain MeaB PF03308.16 ETZ07627.1 - 0.11 11.4 0.1 0.82 8.6 0.1 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB T2SSE PF00437.20 ETZ07627.1 - 0.14 11.2 0.5 1.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein BCA_ABC_TP_C PF12399.8 ETZ07627.1 - 0.15 12.0 7.1 0.49 10.4 0.1 3.2 3 0 0 3 3 3 0 Branched-chain amino acid ATP-binding cassette transporter IIGP PF05049.13 ETZ07627.1 - 0.16 11.0 0.3 1.6 7.7 0.1 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_30 PF13604.6 ETZ07627.1 - 0.18 11.5 0.2 4.9 6.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 ETZ07627.1 - 0.21 11.3 0.1 2 8.1 0.0 2.5 3 0 0 3 3 2 0 IstB-like ATP binding protein zinc_ribbon_9 PF14369.6 ETZ07627.1 - 8.6 6.7 7.3 19 5.6 0.8 3.2 3 0 0 3 3 2 0 zinc-ribbon ABC_tran PF00005.27 ETZ07630.1 - 2.4e-32 112.3 0.0 4.1e-32 111.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 ETZ07630.1 - 1e-14 54.5 0.0 2.7e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 TOBE domain AAA_21 PF13304.6 ETZ07630.1 - 7.4e-09 35.8 0.3 0.00014 21.8 0.0 2.4 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ETZ07630.1 - 5.9e-06 25.9 0.1 0.00017 21.1 0.1 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 ETZ07630.1 - 0.0042 17.3 0.6 0.021 15.1 0.1 2.2 2 1 1 3 3 3 1 AAA domain sCache_3_2 PF17203.4 ETZ07630.1 - 0.0047 17.1 0.4 0.027 14.6 0.1 2.3 2 1 0 2 2 2 1 Single cache domain 3 AAA_23 PF13476.6 ETZ07630.1 - 0.011 16.2 0.0 0.021 15.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 ETZ07630.1 - 0.049 13.9 1.1 0.37 11.1 1.1 2.2 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 ETZ07630.1 - 0.05 14.0 0.8 0.69 10.3 0.8 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 ETZ07630.1 - 0.072 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 ETZ07630.1 - 0.073 13.4 0.2 0.14 12.5 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 ETZ07630.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase CbiA PF01656.23 ETZ07630.1 - 0.14 12.2 0.0 2.1 8.4 0.0 2.1 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Rad17 PF03215.15 ETZ07630.1 - 0.2 11.6 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Response_reg PF00072.24 ETZ07631.1 - 8.4e-26 90.3 0.1 1.5e-25 89.6 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activat PF00158.26 ETZ07631.1 - 1e-15 57.8 0.0 1.7e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 ETZ07631.1 - 6.2e-06 26.4 0.0 1.4e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 ETZ07631.1 - 0.00014 21.5 0.0 0.00072 19.3 0.0 2.2 3 0 0 3 3 3 1 Bacterial regulatory protein, Fis family ALG3 PF05208.13 ETZ07631.1 - 0.00082 18.9 0.4 0.0019 17.7 0.6 1.5 2 0 0 2 2 2 1 ALG3 protein ABC_tran PF00005.27 ETZ07631.1 - 0.0047 17.4 0.2 0.013 16.0 0.0 1.8 2 0 0 2 2 2 1 ABC transporter FleQ PF06490.11 ETZ07631.1 - 0.0065 16.8 0.0 0.035 14.5 0.0 2.2 2 0 0 2 2 2 1 Flagellar regulatory protein FleQ MCM PF00493.23 ETZ07631.1 - 0.021 13.9 0.0 0.044 12.9 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_7 PF12775.7 ETZ07631.1 - 0.029 13.9 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region HTH_1 PF00126.27 ETZ07631.1 - 0.032 14.2 0.0 0.1 12.6 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family AAA PF00004.29 ETZ07631.1 - 0.052 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) B12-binding PF02310.19 ETZ07631.1 - 0.053 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 B12 binding domain AAA_5 PF07728.14 ETZ07631.1 - 0.056 13.4 0.2 0.14 12.2 0.2 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 ETZ07631.1 - 0.07 13.2 0.2 0.17 12.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 ETZ07631.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ETZ07631.1 - 0.12 12.7 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 ETZ07631.1 - 0.14 12.4 0.1 2.6 8.3 0.1 2.5 1 1 0 1 1 1 0 AAA domain FabA PF07977.13 ETZ07632.1 - 7.1e-34 116.4 0.4 8.4e-34 116.2 0.4 1.1 1 0 0 1 1 1 1 FabA-like domain MaoC_dehydratas PF01575.19 ETZ07632.1 - 0.0021 17.6 0.1 0.0032 17.0 0.1 1.4 1 0 0 1 1 1 1 MaoC like domain DUF3445 PF11927.8 ETZ07632.1 - 0.039 13.6 0.0 0.049 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3445) 4HBT PF03061.22 ETZ07632.1 - 0.045 14.1 0.0 0.46 10.9 0.0 2.2 1 1 1 2 2 2 0 Thioesterase superfamily Hexapep PF00132.24 ETZ07633.1 - 6.1e-32 108.2 21.0 3.2e-08 33.0 0.1 6.5 4 1 3 7 7 7 7 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 ETZ07633.1 - 1.3e-13 50.4 19.9 0.0006 19.5 0.4 5.6 4 2 2 6 6 6 4 Hexapeptide repeat of succinyl-transferase LpxD PF04613.14 ETZ07633.1 - 1.7e-05 24.5 0.0 3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD OmpH PF03938.14 ETZ07634.1 - 2.8e-09 37.5 0.1 3.7e-09 37.0 0.1 1.2 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Pyr_redox PF00070.27 ETZ07634.1 - 0.076 13.6 0.1 0.65 10.6 0.0 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SRP54 PF00448.22 ETZ07635.1 - 4.9e-56 189.5 0.1 7.9e-56 188.8 0.1 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 ETZ07635.1 - 9.9e-29 99.9 1.4 9.9e-29 99.9 1.4 2.7 3 0 0 3 3 3 1 Signal peptide binding domain SRP54_N PF02881.19 ETZ07635.1 - 4.4e-15 55.7 0.9 1.1e-14 54.3 0.2 2.1 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain ATP_bind_1 PF03029.17 ETZ07635.1 - 1.4e-06 28.3 0.1 5.1e-06 26.4 0.1 1.9 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 ETZ07635.1 - 1.9e-06 28.2 0.1 8.6e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 ETZ07635.1 - 1.2e-05 25.4 0.0 0.0001 22.4 0.0 2.2 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 ETZ07635.1 - 0.00032 20.6 3.3 0.033 14.1 0.0 3.3 3 1 1 4 4 4 1 AAA domain AAA_16 PF13191.6 ETZ07635.1 - 0.00045 20.6 0.1 0.0032 17.9 0.0 2.2 1 1 0 2 2 2 1 AAA ATPase domain ArsA_ATPase PF02374.15 ETZ07635.1 - 0.00046 19.5 0.2 0.051 12.7 0.0 2.8 3 0 0 3 3 3 1 Anion-transporting ATPase AAA_18 PF13238.6 ETZ07635.1 - 0.00072 20.1 0.1 0.0022 18.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 ETZ07635.1 - 0.0011 18.5 0.1 0.0027 17.2 0.1 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region Arf PF00025.21 ETZ07635.1 - 0.0092 15.4 0.3 0.043 13.3 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_14 PF13173.6 ETZ07635.1 - 0.011 15.8 0.0 0.026 14.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ETZ07635.1 - 0.017 15.2 0.1 0.2 11.8 0.0 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase ATPase PF06745.13 ETZ07635.1 - 0.019 14.3 0.0 0.042 13.2 0.0 1.6 1 0 0 1 1 1 0 KaiC SRPRB PF09439.10 ETZ07635.1 - 0.025 14.0 0.8 0.25 10.8 0.8 2.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit NACHT PF05729.12 ETZ07635.1 - 0.047 13.6 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.6 ETZ07635.1 - 0.059 13.8 0.9 0.35 11.3 0.2 2.7 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 ETZ07635.1 - 0.064 13.0 0.1 0.16 11.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 ETZ07635.1 - 0.069 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 ETZ07635.1 - 0.077 12.7 0.6 0.22 11.2 0.1 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 ETZ07635.1 - 0.078 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 ETZ07635.1 - 0.13 12.7 1.2 0.32 11.5 0.5 2.4 2 1 0 2 2 2 0 ABC transporter BPD_transp_1 PF00528.22 ETZ07640.1 - 1.5e-11 44.4 19.5 1.5e-11 44.4 19.5 2.2 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component MipZ PF09140.11 ETZ07641.1 - 7.4e-62 209.0 0.0 9.2e-62 208.7 0.0 1.0 1 0 0 1 1 1 1 ATPase MipZ CbiA PF01656.23 ETZ07641.1 - 3.1e-06 27.3 0.0 4.9e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 ETZ07641.1 - 2e-05 24.2 0.0 4.4e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase AAA_31 PF13614.6 ETZ07641.1 - 0.0002 21.3 0.1 0.00048 20.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 ETZ07641.1 - 0.002 17.7 0.1 0.006 16.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 ETZ07641.1 - 0.06 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.15 ETZ07641.1 - 0.094 12.0 0.0 0.26 10.6 0.0 1.7 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain Peptidase_S41 PF03572.18 ETZ07642.1 - 1.8e-44 151.3 0.1 2.9e-44 150.6 0.1 1.4 1 0 0 1 1 1 1 Peptidase family S41 PDZ_2 PF13180.6 ETZ07642.1 - 5.5e-07 29.8 1.1 1.2e-06 28.8 0.1 2.1 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 ETZ07642.1 - 4.6e-06 26.4 0.0 9.9e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 ETZ07642.1 - 2.7e-05 24.4 1.1 0.00019 21.7 0.1 2.5 2 0 0 2 2 2 1 PDZ domain DUF1797 PF08796.10 ETZ07642.1 - 0.059 13.5 0.5 0.14 12.3 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1797) GRASP55_65 PF04495.14 ETZ07642.1 - 0.079 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain CDP-OH_P_transf PF01066.21 ETZ07643.1 - 3.7e-15 56.5 1.2 3.7e-15 56.5 1.2 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Insulin_TMD PF17870.1 ETZ07643.1 - 0.15 12.2 0.8 0.37 10.9 0.8 1.8 1 1 0 1 1 1 0 Insulin receptor trans-membrane segment Elongin_A PF06881.11 ETZ07644.1 - 1.5 9.3 9.7 12 6.5 1.8 2.8 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A ING PF12998.7 ETZ07644.1 - 8.6 7.0 10.3 3.7 8.2 1.7 3.1 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding MazG PF03819.17 ETZ07645.1 - 0.026 14.7 2.8 4.4 7.5 0.2 2.4 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain VPR PF00522.18 ETZ07645.1 - 0.11 12.5 0.0 15 5.7 0.0 2.3 2 0 0 2 2 2 0 VPR/VPX protein DUF4363 PF14276.6 ETZ07645.1 - 1.1 9.4 6.7 5.5 7.1 1.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) DUF2380 PF09533.10 ETZ07646.1 - 0.012 15.2 0.4 0.016 14.8 0.4 1.2 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) PG_isomerase_N PF18353.1 ETZ07647.1 - 0.027 14.8 0.8 0.1 13.0 0.0 2.3 3 0 0 3 3 3 0 Phosphoglucose isomerase N-terminal domain PG_isomerase_N PF18353.1 ETZ07650.1 - 0.024 15.0 0.5 0.11 13.0 0.0 2.2 3 0 0 3 3 3 0 Phosphoglucose isomerase N-terminal domain KapB PF08810.10 ETZ07651.1 - 0.019 15.1 0.2 0.023 14.9 0.2 1.1 1 0 0 1 1 1 0 Kinase associated protein B HDA2-3 PF11496.8 ETZ07651.1 - 0.037 13.2 0.2 0.046 12.9 0.2 1.0 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 Tweety PF04906.13 ETZ07651.1 - 0.11 11.1 0.1 0.12 11.1 0.1 1.1 1 0 0 1 1 1 0 Tweety DUF1617 PF07761.12 ETZ07653.1 - 0.063 13.4 0.1 0.17 12.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1617) SBP_bac_5 PF00496.22 ETZ07654.1 - 1.7e-39 135.8 0.0 2.2e-39 135.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle DUF1033 PF06279.11 ETZ07654.1 - 1.2 9.3 5.7 6.4 7.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1033) FAD_binding_3 PF01494.19 ETZ07655.1 - 1.1e-15 57.7 0.1 1.2e-14 54.3 0.1 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 ETZ07655.1 - 7.4e-05 22.5 0.5 0.00014 21.6 0.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ETZ07655.1 - 0.00031 20.1 0.2 0.0017 17.7 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ETZ07655.1 - 0.0014 17.5 0.4 0.37 9.6 0.4 2.3 2 0 0 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.14 ETZ07655.1 - 0.0025 16.6 0.3 0.0081 14.9 0.2 1.7 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 ETZ07655.1 - 0.003 17.7 0.9 0.0071 16.5 0.9 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ETZ07655.1 - 0.0064 15.6 0.6 0.011 14.8 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 ETZ07655.1 - 0.007 15.5 0.0 0.011 14.8 0.0 1.5 1 1 0 1 1 1 1 Squalene epoxidase Thi4 PF01946.17 ETZ07655.1 - 0.06 12.6 0.3 0.12 11.6 0.3 1.4 1 0 0 1 1 1 0 Thi4 family Claudin_3 PF06653.11 ETZ07655.1 - 0.072 13.0 0.4 0.14 12.0 0.0 1.6 2 0 0 2 2 2 0 Tight junction protein, Claudin-like GIDA PF01134.22 ETZ07655.1 - 0.21 10.6 0.5 0.92 8.5 0.6 1.7 1 1 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.16 ETZ07655.1 - 0.23 11.1 0.3 0.43 10.2 0.3 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 ETZ07657.1 - 2.1e-17 63.5 0.1 1.7e-12 47.6 0.0 2.3 1 1 1 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 ETZ07657.1 - 5.4e-17 62.4 0.0 9.3e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus UPF0113 PF03657.13 ETZ07657.1 - 0.095 13.0 0.0 0.41 11.0 0.0 2.0 2 0 0 2 2 2 0 UPF0113 PUA domain PAPS_reduct PF01507.19 ETZ07658.1 - 0.028 14.5 0.0 0.029 14.4 0.0 1.3 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family DUF2524 PF10732.9 ETZ07658.1 - 0.043 14.1 0.2 0.059 13.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) Bax1-I PF01027.20 ETZ07659.1 - 9.1e-53 179.2 25.3 1.1e-52 178.9 25.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF5357 PF17310.2 ETZ07659.1 - 2.8 6.4 7.3 1.5 7.3 5.7 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5357) IncD PF17628.2 ETZ07659.1 - 8.6 6.1 8.2 0.76 9.6 2.8 2.0 1 1 1 2 2 2 0 Inclusion membrane protein D Popeye PF04831.13 ETZ07659.1 - 9.3 6.4 8.0 0.6 10.3 1.7 2.0 1 1 2 3 3 3 0 Popeye protein conserved region DUF374 PF04028.13 ETZ07661.1 - 5.6e-23 80.3 0.1 9.5e-23 79.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF374) DUF21 PF01595.20 ETZ07662.1 - 1.4e-30 106.3 6.4 2.1e-30 105.7 6.4 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 ETZ07662.1 - 1.3e-16 60.8 0.0 3e-08 34.0 0.0 3.4 3 0 0 3 3 3 2 CBS domain CorC_HlyC PF03471.17 ETZ07662.1 - 6.6e-15 54.9 0.0 1.6e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 Transporter associated domain SKI PF01202.22 ETZ07663.1 - 4.6e-30 104.8 0.0 1.7e-29 103.0 0.0 1.7 1 1 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 ETZ07663.1 - 1.2e-07 32.3 0.0 2.1e-06 28.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.6 ETZ07663.1 - 5.1e-05 23.5 0.3 7.2e-05 23.0 0.0 1.5 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_17 PF13207.6 ETZ07663.1 - 0.00043 20.7 0.1 0.0017 18.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 ETZ07663.1 - 0.00087 19.7 0.0 0.0016 18.9 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CoaE PF01121.20 ETZ07663.1 - 0.0018 17.9 0.0 0.0029 17.3 0.0 1.2 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_22 PF13401.6 ETZ07663.1 - 0.0019 18.5 0.0 0.0076 16.5 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 ETZ07663.1 - 0.0052 17.0 0.0 0.0081 16.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 ETZ07663.1 - 0.0099 15.6 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ETZ07663.1 - 0.01 16.2 0.1 0.028 14.8 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 ETZ07663.1 - 0.025 13.8 0.1 0.065 12.4 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain ABC_tran PF00005.27 ETZ07663.1 - 0.027 15.0 0.0 0.064 13.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 ETZ07663.1 - 0.058 13.6 0.0 0.077 13.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 ETZ07663.1 - 0.064 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 ETZ07663.1 - 0.065 13.0 0.0 0.093 12.5 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain MMR_HSR1 PF01926.23 ETZ07663.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase dNK PF01712.19 ETZ07663.1 - 0.13 12.1 0.2 0.91 9.3 0.0 2.3 2 1 0 3 3 3 0 Deoxynucleoside kinase GRP PF07172.11 ETZ07664.1 - 0.0067 17.1 0.8 0.0071 17.0 0.8 1.1 1 0 0 1 1 1 1 Glycine rich protein family Siah-Interact_N PF09032.11 ETZ07665.1 - 0.13 12.5 0.4 0.13 12.5 0.4 3.2 4 0 0 4 4 4 0 Siah interacting protein, N terminal Spore_II_R PF09551.10 ETZ07665.1 - 1.1 9.8 4.5 0.41 11.1 0.1 2.5 3 0 0 3 3 3 0 Stage II sporulation protein R (spore_II_R) YfiO PF13525.6 ETZ07666.1 - 3e-47 161.0 4.4 3.9e-47 160.6 4.4 1.2 1 0 0 1 1 1 1 Outer membrane lipoprotein TPR_18 PF13512.6 ETZ07666.1 - 2.9e-20 72.9 6.8 4.7e-20 72.2 3.1 2.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 ETZ07666.1 - 1.7e-07 31.8 0.0 0.0013 19.3 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 ETZ07666.1 - 7.1e-06 26.3 7.2 0.51 11.1 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_21 PF09976.9 ETZ07666.1 - 0.00019 21.2 0.5 0.001 18.8 0.2 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat-like domain TPR_19 PF14559.6 ETZ07666.1 - 0.083 13.4 0.0 2.8 8.5 0.0 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat Stanniocalcin PF03298.13 ETZ07666.1 - 0.12 11.7 0.2 0.22 10.8 0.0 1.5 2 0 0 2 2 2 0 Stanniocalcin family RTC4 PF14474.6 ETZ07666.1 - 0.14 12.3 0.3 0.33 11.1 0.0 1.8 2 0 0 2 2 2 0 RTC4-like domain TPR_2 PF07719.17 ETZ07666.1 - 0.39 10.9 4.1 61 4.1 0.2 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ETZ07666.1 - 2.3 8.5 8.5 2.4 8.5 3.5 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DivIC PF04977.15 ETZ07667.1 - 0.032 14.0 0.1 0.039 13.7 0.1 1.1 1 0 0 1 1 1 0 Septum formation initiator UPF0086 PF01868.16 ETZ07667.1 - 0.12 12.3 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function UPF0086 Tnp_22_trimer PF17489.2 ETZ07667.1 - 0.16 12.0 2.1 0.28 11.2 2.1 1.4 1 0 0 1 1 1 0 L1 transposable element trimerization domain ParBc PF02195.18 ETZ07668.1 - 1.3e-27 95.9 0.1 2.5e-27 95.0 0.1 1.5 1 0 0 1 1 1 1 ParB-like nuclease domain HTH_ParB PF17762.1 ETZ07668.1 - 1e-13 50.8 3.3 1.7e-13 50.1 0.4 2.6 3 0 0 3 3 3 1 HTH domain found in ParB protein DUF2225 PF09986.9 ETZ07668.1 - 0.0022 17.8 0.8 0.0071 16.1 0.3 1.8 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) CdiA_C_tRNase PF18664.1 ETZ07668.1 - 0.0025 18.0 0.1 0.0056 16.9 0.1 1.6 1 0 0 1 1 1 1 CdiA C-terminal tRNase domain Latarcin PF10279.9 ETZ07668.1 - 0.0059 17.0 0.1 0.0059 17.0 0.1 2.0 2 1 0 2 2 2 1 Latarcin precursor HTH_3 PF01381.22 ETZ07668.1 - 0.018 15.1 0.0 0.054 13.6 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix TrmB PF01978.19 ETZ07668.1 - 0.064 13.1 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB SoPB_HTH PF18090.1 ETZ07668.1 - 0.092 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Centromere-binding protein HTH domain Maf PF02545.14 ETZ07669.1 - 6.8e-07 29.3 0.0 8.4e-07 29.0 0.0 1.3 1 1 0 1 1 1 1 Maf-like protein DUF1048 PF06304.11 ETZ07670.1 - 0.045 14.2 0.2 0.92 10.0 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1048) GLYCAM-1 PF05242.11 ETZ07670.1 - 0.061 13.4 8.0 0.13 12.4 7.0 2.0 2 0 0 2 2 2 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) Prominin PF05478.11 ETZ07670.1 - 1 7.2 6.0 0.46 8.4 2.7 1.9 2 0 0 2 2 2 0 Prominin Thioredoxin_4 PF13462.6 ETZ07670.1 - 5.7 7.1 7.6 1.2 9.2 3.3 2.0 2 0 0 2 2 2 0 Thioredoxin PD40 PF07676.12 ETZ07671.1 - 3.6e-13 49.1 6.1 9.7e-07 28.6 0.1 4.4 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat TolB_N PF04052.13 ETZ07671.1 - 0.00026 21.1 0.0 0.00047 20.3 0.0 1.4 1 0 0 1 1 1 1 TolB amino-terminal domain DPPIV_N PF00930.21 ETZ07671.1 - 0.0069 15.2 0.0 3.6 6.3 0.0 2.8 1 1 2 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Gmad1 PF10647.9 ETZ07671.1 - 0.021 14.6 0.0 0.088 12.5 0.0 2.0 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain Peptidase_M24 PF00557.24 ETZ07672.1 - 8.3e-37 126.9 0.0 1.1e-36 126.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 ETZ07672.1 - 5.9e-16 58.3 0.5 1.1e-15 57.4 0.0 1.8 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 ETZ07672.1 - 0.2 12.3 0.0 0.44 11.2 0.0 1.6 1 0 0 1 1 1 0 Creatinase/Prolidase N-terminal domain SIT PF15330.6 ETZ07673.1 - 0.15 12.5 4.6 0.061 13.8 1.9 1.6 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT PA26 PF04636.13 ETZ07673.1 - 0.21 10.5 8.6 0.26 10.2 8.6 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Synaptobrevin PF00957.21 ETZ07673.1 - 2.3 8.0 10.7 0.98 9.3 4.3 2.7 1 1 1 2 2 2 0 Synaptobrevin SID-1_RNA_chan PF13965.6 ETZ07673.1 - 3.6 5.9 7.9 5.5 5.3 7.9 1.5 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 Hid1 PF12722.7 ETZ07673.1 - 4.7 5.2 16.9 5.5 5.0 16.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DDE_Tnp_1_assoc PF13808.6 ETZ07676.1 - 9e-17 60.9 0.0 1.2e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 DDE_Tnp_1-associated eIF3_p135 PF12807.7 ETZ07678.1 - 0.13 12.3 0.9 0.41 10.7 0.3 1.9 1 1 1 2 2 2 0 Translation initiation factor eIF3 subunit 135 TetR_C_3 PF08362.11 ETZ07679.1 - 0.092 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 YcdC-like protein, C-terminal region adh_short_C2 PF13561.6 ETZ07680.1 - 2.2e-47 161.6 0.0 2.7e-47 161.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETZ07680.1 - 2.1e-34 118.7 0.1 2.5e-34 118.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETZ07680.1 - 7.6e-10 39.0 0.0 1.7e-09 37.8 0.0 1.6 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.8 ETZ07680.1 - 0.024 14.4 0.0 0.063 13.1 0.0 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase MRP-S23 PF10484.9 ETZ07681.1 - 0.55 10.5 5.1 8.2 6.7 0.9 2.3 1 1 0 2 2 2 0 Mitochondrial ribosomal protein S23 DUF3800 PF12686.7 ETZ07681.1 - 5.2 7.7 10.0 84 3.8 10.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Alveol-reg_P311 PF11092.8 ETZ07682.1 - 0.031 14.4 0.1 0.071 13.2 0.1 1.6 1 0 0 1 1 1 0 Neuronal protein 3.1 (p311) RadC PF04002.15 ETZ07683.1 - 1.9e-37 127.9 0.0 2.9e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 RadC-like JAB domain Prok-JAB PF14464.6 ETZ07683.1 - 0.043 13.6 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain HTH_Tnp_IS630 PF01710.16 ETZ07685.1 - 0.012 15.6 0.0 0.016 15.3 0.0 1.1 1 0 0 1 1 1 0 Transposase DDE_3 PF13358.6 ETZ07686.1 - 5.3e-07 29.5 0.0 5.5e-07 29.4 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease MFS_1 PF07690.16 ETZ07687.1 - 1.3e-29 103.3 42.9 1.3e-29 103.3 42.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Herpes_UL49_5 PF05702.11 ETZ07687.1 - 0.0088 16.1 0.8 0.0088 16.1 0.8 3.1 1 1 2 3 3 3 1 Herpesvirus UL49.5 envelope/tegument protein HCNGP PF07818.13 ETZ07689.1 - 0.11 13.1 4.7 1.5 9.5 0.1 4.4 2 1 1 3 3 3 0 HCNGP-like protein DUF1363 PF07101.11 ETZ07689.1 - 0.12 12.7 0.4 27 5.1 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1363) YcgL PF05166.13 ETZ07689.1 - 0.24 11.8 1.4 59 4.1 0.0 4.3 2 1 1 3 3 3 0 YcgL domain DciA PF05258.12 ETZ07690.1 - 4.1e-11 43.1 0.0 7.5e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Dna[CI] antecedent, DciA DUF179 PF02622.15 ETZ07691.1 - 5.2e-25 88.3 0.0 6.3e-25 88.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 Peptidase_M17 PF00883.21 ETZ07693.1 - 1.4e-110 369.5 0.0 1.6e-110 369.2 0.0 1.0 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_A8 PF01252.18 ETZ07694.1 - 2e-31 109.1 8.6 2.5e-31 108.8 8.6 1.1 1 0 0 1 1 1 1 Signal peptidase (SPase) II DUF2919 PF11143.8 ETZ07694.1 - 0.026 14.9 1.0 0.026 14.9 1.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2919) ECF_trnsprt PF12822.7 ETZ07694.1 - 0.04 14.0 9.2 0.36 10.9 9.2 2.0 1 1 0 1 1 1 0 ECF transporter, substrate-specific component DUF4131 PF13567.6 ETZ07694.1 - 0.32 10.7 2.7 2.5 7.7 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF3035 PF11233.8 ETZ07695.1 - 0.0039 17.5 0.2 0.006 16.9 0.2 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3035) DnaJ_C PF01556.18 ETZ07697.1 - 2.9e-32 111.8 0.0 3.7e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ETZ07697.1 - 1.7e-25 88.9 3.5 3.1e-25 88.1 3.5 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 ETZ07697.1 - 2.8e-11 43.6 19.1 6.9e-11 42.3 19.1 1.7 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 ETZ07697.1 - 0.78 9.7 17.9 0.44 10.5 5.2 2.7 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-CHY PF05495.12 ETZ07697.1 - 2.5 8.6 6.6 1 9.9 3.7 1.7 1 1 0 1 1 1 0 CHY zinc finger Ribosomal_L17 PF01196.19 ETZ07698.1 - 2.7e-26 92.3 0.0 3.4e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L17 RNA_pol_A_CTD PF03118.15 ETZ07699.1 - 2.3e-21 75.3 0.0 4e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain RNA_pol_L PF01193.24 ETZ07699.1 - 9.5e-21 73.0 0.0 1.4e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_A_bac PF01000.26 ETZ07699.1 - 3.1e-15 56.5 0.0 1.3e-14 54.5 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L_2 PF13656.6 ETZ07699.1 - 0.099 12.4 0.0 0.44 10.4 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Ribosomal_S11 PF00411.19 ETZ07700.1 - 3.2e-39 133.7 0.3 3.7e-39 133.5 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 DmpG_comm PF07836.11 ETZ07700.1 - 0.084 12.4 0.1 0.24 11.0 0.0 1.8 1 1 1 2 2 2 0 DmpG-like communication domain Ribosomal_S13 PF00416.22 ETZ07701.1 - 9.6e-27 93.9 5.3 2.8e-25 89.2 5.3 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 ETZ07701.1 - 0.0096 14.7 0.0 0.0098 14.7 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_5 PF14520.6 ETZ07701.1 - 0.035 14.7 0.1 0.1 13.2 0.0 1.8 1 1 1 2 2 2 0 Helix-hairpin-helix domain MU2_FHA PF18221.1 ETZ07701.1 - 0.039 14.0 0.1 0.054 13.5 0.1 1.2 1 0 0 1 1 1 0 Mutator 2 Fork head associated domain OmpA PF00691.20 ETZ07702.1 - 9.3e-15 54.8 0.0 1.3e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 OmpA family Sod_Fe_C PF02777.18 ETZ07704.1 - 2.8e-30 104.5 2.7 2.8e-30 104.5 2.7 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 ETZ07704.1 - 2e-20 73.0 2.5 2e-20 73.0 2.5 2.4 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Somatostatin PF03002.15 ETZ07704.1 - 0.021 14.8 0.3 0.021 14.8 0.3 1.9 2 0 0 2 2 2 0 Somatostatin/Cortistatin family Glycos_transf_1 PF00534.20 ETZ07705.1 - 8.6e-28 97.0 0.0 1.3e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ETZ07705.1 - 2e-24 86.5 0.0 3.3e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ETZ07705.1 - 3.3e-08 33.7 0.1 6.7e-08 32.7 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 ETZ07705.1 - 1.2e-07 32.0 0.0 5.4e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 ETZ07705.1 - 0.00029 21.3 0.0 0.0011 19.4 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain HTH_33 PF13592.6 ETZ07706.1 - 0.014 15.0 0.4 0.021 14.5 0.4 1.5 1 1 0 1 1 1 0 Winged helix-turn helix DUF3853 PF12964.7 ETZ07706.1 - 0.046 13.9 0.0 0.07 13.3 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3853) OrfB_IS605 PF01385.19 ETZ07706.1 - 0.26 11.5 2.5 0.31 11.3 2.4 1.2 1 1 0 1 1 1 0 Probable transposase DDE_Tnp_IS1 PF03400.13 ETZ07707.1 - 2.8e-11 43.9 2.3 3.3e-11 43.6 2.3 1.1 1 0 0 1 1 1 1 IS1 transposase DDE_Tnp_IS240 PF13610.6 ETZ07707.1 - 0.033 14.4 2.9 0.075 13.3 2.9 1.5 1 1 0 1 1 1 0 DDE domain DeoRC PF00455.22 ETZ07707.1 - 0.039 13.9 0.0 0.052 13.5 0.0 1.1 1 0 0 1 1 1 0 DeoR C terminal sensor domain PLA2_B PF01735.18 ETZ07707.1 - 0.055 11.9 0.6 0.11 10.8 0.3 1.5 1 1 1 2 2 2 0 Lysophospholipase catalytic domain APOC4 PF15119.6 ETZ07707.1 - 0.14 12.4 1.4 0.21 11.9 0.6 1.6 2 0 0 2 2 2 0 Apolipoprotein C4 Alpha_Helical PF18489.1 ETZ07709.1 - 0.23 11.6 1.9 1.9 8.7 0.0 3.2 3 0 0 3 3 3 0 Alpha helical domain CENP-H PF05837.12 ETZ07711.1 - 0.43 11.0 6.0 5.2 7.5 1.4 2.8 3 0 0 3 3 3 0 Centromere protein H (CENP-H) FA_synthesis PF02504.15 ETZ07712.1 - 5.3e-87 291.9 0.0 6.1e-87 291.7 0.0 1.0 1 0 0 1 1 1 1 Fatty acid synthesis protein Ribosomal_L32p PF01783.23 ETZ07713.1 - 7e-15 55.0 2.5 7e-15 55.0 2.5 1.4 2 0 0 2 2 2 1 Ribosomal L32p protein family zf-UBP PF02148.19 ETZ07713.1 - 0.013 15.9 0.7 0.013 15.9 0.7 1.6 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Ribosomal_L37e PF01907.19 ETZ07713.1 - 0.023 14.9 2.0 0.036 14.2 2.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L37e Anti-TRAP PF15777.5 ETZ07713.1 - 0.037 14.0 0.3 0.046 13.7 0.3 1.1 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF4096 PF13340.6 ETZ07715.1 - 1.6e-17 63.4 1.5 2.1e-17 63.1 1.5 1.1 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) Peptidase_S11 PF00768.20 ETZ07717.1 - 3.5e-33 115.0 0.0 4.3e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 ETZ07717.1 - 0.02 14.5 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase enzyme family DUF4191 PF13829.6 ETZ07717.1 - 0.036 13.4 0.4 0.064 12.6 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Peptidase_S11 PF00768.20 ETZ07718.1 - 1.8e-05 24.3 0.0 1.9e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase DUF4498 PF14926.6 ETZ07718.1 - 0.09 12.1 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4498) RecA PF00154.21 ETZ07720.1 - 1.5e-135 450.8 2.1 1.7e-135 450.6 2.1 1.0 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 ETZ07720.1 - 1.9e-13 50.2 1.0 8.7e-13 48.1 1.0 1.8 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 ETZ07720.1 - 1.1e-09 38.0 4.6 6.9e-07 28.8 0.2 3.6 2 1 1 3 3 3 2 KaiC ATPase_2 PF01637.18 ETZ07720.1 - 1.1e-06 28.8 0.0 2.3e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 ETZ07720.1 - 7.4e-06 25.8 0.0 2.1e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 ETZ07720.1 - 0.00044 20.7 0.0 0.00086 19.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_35 PF14516.6 ETZ07720.1 - 0.0079 15.1 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_16 PF13191.6 ETZ07720.1 - 0.012 16.0 0.0 0.024 15.0 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 ETZ07720.1 - 0.031 14.8 0.0 0.085 13.4 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 ETZ07720.1 - 0.06 13.4 0.0 0.38 10.8 0.0 2.2 1 1 1 2 2 2 0 AAA domain CobU PF02283.16 ETZ07720.1 - 0.081 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase MobB PF03205.14 ETZ07720.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PAXNEB PF05625.11 ETZ07720.1 - 0.13 11.4 0.4 0.21 10.7 0.4 1.3 1 0 0 1 1 1 0 PAXNEB protein HSP70 PF00012.20 ETZ07721.1 - 1.4e-259 862.3 9.0 1.6e-259 862.2 9.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ETZ07721.1 - 1e-17 64.0 3.2 2.8e-14 52.7 0.6 2.6 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 ETZ07721.1 - 0.00057 20.3 3.3 0.52 10.8 0.0 3.6 3 0 0 3 3 3 2 Cell division protein FtsA DDE_Tnp_4 PF13359.6 ETZ07721.1 - 0.006 16.3 0.0 0.04 13.6 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease DUF3153 PF11353.8 ETZ07721.1 - 0.019 14.6 0.0 0.048 13.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) DeoC PF01791.9 ETZ07721.1 - 0.024 14.3 0.2 7.5 6.1 0.0 2.7 3 0 0 3 3 3 0 DeoC/LacD family aldolase Hydantoinase_A PF01968.18 ETZ07721.1 - 0.19 10.9 1.8 1.6 7.9 0.1 3.0 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase Allexi_40kDa PF05549.11 ETZ07721.1 - 1.5 8.3 5.4 2.7 7.4 5.4 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein Bac_DNA_binding PF00216.21 ETZ07722.1 - 7.4e-23 80.6 0.0 1.2e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-CCDC81_euk_2 PF18289.1 ETZ07722.1 - 0.00058 20.0 0.0 0.00096 19.3 0.0 1.4 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 HU-CCDC81_bac_2 PF18175.1 ETZ07722.1 - 0.0033 17.3 0.0 0.0062 16.4 0.0 1.5 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 HU-HIG PF18291.1 ETZ07722.1 - 0.0041 17.2 0.0 0.0063 16.6 0.0 1.3 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_bac_1 PF18174.1 ETZ07722.1 - 0.068 13.1 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 1 adh_short_C2 PF13561.6 ETZ07724.1 - 1.1e-52 179.0 0.0 1.2e-52 178.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETZ07724.1 - 2.1e-52 177.4 0.0 2.5e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETZ07724.1 - 2e-14 53.9 0.1 3.3e-14 53.2 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ETZ07724.1 - 0.0044 16.9 0.0 0.0055 16.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ETZ07724.1 - 0.013 15.1 0.0 0.034 13.7 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family Epimerase PF01370.21 ETZ07724.1 - 0.035 13.6 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ETZ07724.1 - 0.07 12.5 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Lactamase_B_2 PF12706.7 ETZ07725.1 - 3.2e-24 85.6 0.1 4.6e-24 85.1 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ETZ07725.1 - 4.7e-08 33.3 0.4 7.4e-08 32.6 0.2 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 ETZ07725.1 - 0.084 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain Poty_PP PF08440.10 ETZ07726.1 - 0.0009 18.4 1.0 0.0012 17.9 1.0 1.3 1 0 0 1 1 1 1 Potyviridae polyprotein DUF4618 PF15397.6 ETZ07726.1 - 0.0015 18.0 2.8 0.014 14.9 0.5 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4618) MitMem_reg PF13012.6 ETZ07726.1 - 0.0029 18.0 1.0 0.023 15.1 1.0 2.0 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function ISG65-75 PF11727.8 ETZ07726.1 - 0.046 12.9 2.2 0.25 10.5 0.0 2.0 1 1 1 2 2 2 0 Invariant surface glycoprotein AI-2E_transport PF01594.16 ETZ07726.1 - 0.24 10.5 2.4 0.86 8.7 0.3 2.0 2 0 0 2 2 2 0 AI-2E family transporter FlxA PF14282.6 ETZ07726.1 - 0.4 10.7 4.7 11 6.0 1.7 2.2 2 0 0 2 2 2 0 FlxA-like protein GatB_N PF02934.15 ETZ07727.1 - 2.4e-103 345.3 0.0 4.4e-103 344.4 0.0 1.4 2 0 0 2 2 2 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 ETZ07727.1 - 6.8e-27 94.2 1.5 1.1e-26 93.5 1.5 1.3 1 0 0 1 1 1 1 GatB domain DUF520 PF04461.13 ETZ07727.1 - 0.079 13.1 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF520) Peptidase_S24 PF00717.23 ETZ07728.1 - 7e-19 67.6 0.0 1.3e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 ETZ07728.1 - 0.0029 17.4 0.1 0.39 10.5 0.0 2.8 2 1 0 2 2 2 2 Signal peptidase, peptidase S26 GIY-YIG PF01541.24 ETZ07729.1 - 1.3e-07 31.7 0.0 1.6e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 GIY-YIG catalytic domain UvrC_HhH_N PF08459.11 ETZ07730.1 - 5.2e-36 123.9 0.0 9.8e-36 123.0 0.0 1.5 1 0 0 1 1 1 1 UvrC Helix-hairpin-helix N-terminal HHH_5 PF14520.6 ETZ07730.1 - 8.8e-07 29.4 0.2 4.5e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH PF00633.23 ETZ07730.1 - 1.2e-06 28.1 0.0 0.0017 18.2 0.0 2.5 2 0 0 2 2 2 2 Helix-hairpin-helix motif UVR PF02151.19 ETZ07730.1 - 3.2e-05 23.5 1.8 8.4e-05 22.2 1.8 1.7 1 0 0 1 1 1 1 UvrB/uvrC motif HHH_2 PF12826.7 ETZ07730.1 - 0.00025 21.1 0.0 0.00071 19.6 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_8 PF14716.6 ETZ07730.1 - 0.011 16.0 0.5 2.2 8.7 0.0 3.4 2 1 1 3 3 3 0 Helix-hairpin-helix domain HHH_3 PF12836.7 ETZ07730.1 - 0.042 14.1 0.1 0.24 11.7 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif TatD_DNase PF01026.21 ETZ07731.1 - 1.8e-67 227.4 0.0 2e-67 227.3 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase PPR PF01535.20 ETZ07731.1 - 0.075 13.3 0.0 0.2 12.0 0.0 1.8 1 0 0 1 1 1 0 PPR repeat DDE_Tnp_ISAZ013 PF07592.11 ETZ07735.1 - 9.2e-16 57.7 1.4 9.7e-16 57.6 1.4 1.0 1 0 0 1 1 1 1 Rhodopirellula transposase DDE domain MFS_1 PF07690.16 ETZ07736.1 - 4.6e-36 124.5 80.5 8.5e-28 97.3 46.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 ETZ07736.1 - 0.0017 16.7 2.6 0.0017 16.7 2.6 2.7 3 1 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Folate_carrier PF01770.18 ETZ07736.1 - 0.41 9.3 12.6 0.017 13.9 3.2 2.2 2 0 0 2 2 2 0 Reduced folate carrier MMPL PF03176.15 ETZ07736.1 - 1.3 7.9 5.4 0.28 10.1 1.0 1.9 2 0 0 2 2 2 0 MMPL family Auts2 PF15336.6 ETZ07737.1 - 0.0045 17.1 0.4 0.0047 17.1 0.4 1.0 1 0 0 1 1 1 1 Autism susceptibility gene 2 protein TALPID3 PF15324.6 ETZ07737.1 - 0.81 7.3 4.2 0.85 7.2 4.2 1.0 1 0 0 1 1 1 0 Hedgehog signalling target rve_3 PF13683.6 ETZ07738.1 - 0.095 12.5 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Integrase core domain CUE PF02845.16 ETZ07739.1 - 0.00021 20.9 0.0 0.00026 20.6 0.0 1.1 1 0 0 1 1 1 1 CUE domain BRCT PF00533.26 ETZ07739.1 - 0.0011 19.3 0.0 0.0011 19.3 0.0 1.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain HTH_28 PF13518.6 ETZ07740.1 - 0.005 16.9 0.0 0.0066 16.6 0.0 1.3 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 ETZ07740.1 - 0.0057 16.4 0.0 0.0076 16.0 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain BrkDBD PF09607.10 ETZ07740.1 - 0.006 16.3 0.2 0.0087 15.8 0.1 1.4 1 1 0 1 1 1 1 Brinker DNA-binding domain HTH_Tnp_1 PF01527.20 ETZ07740.1 - 0.012 15.9 0.0 0.015 15.6 0.0 1.1 1 0 0 1 1 1 0 Transposase CENP-B_N PF04218.13 ETZ07740.1 - 0.02 14.5 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain UvrD-helicase PF00580.21 ETZ07741.1 - 8.8e-64 216.0 0.1 1.5e-63 215.3 0.1 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 ETZ07741.1 - 9.1e-22 78.0 0.0 4.8e-21 75.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain UvrD_C PF13361.6 ETZ07741.1 - 2.3e-17 63.4 0.0 5e-13 49.1 0.0 3.1 3 0 0 3 3 3 2 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 ETZ07741.1 - 6.2e-11 41.9 0.3 9.5e-05 22.2 0.5 2.5 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 ETZ07741.1 - 2.4e-05 24.1 0.0 0.015 15.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 ETZ07741.1 - 7.7e-05 23.0 0.1 0.35 11.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain PhoH PF02562.16 ETZ07741.1 - 0.00017 21.1 0.0 0.012 15.1 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein DEAD PF00270.29 ETZ07741.1 - 0.026 14.3 0.0 0.083 12.7 0.0 1.9 1 1 0 1 1 1 0 DEAD/DEAH box helicase MFS_1 PF07690.16 ETZ07742.1 - 3.1e-25 88.9 34.6 3.1e-25 88.9 34.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MMR_HSR1 PF01926.23 ETZ07743.1 - 5.8e-20 71.5 0.0 8.1e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ETZ07743.1 - 3e-08 33.3 0.0 4.1e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 ETZ07743.1 - 2.4e-06 27.6 0.1 0.00011 22.2 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 ETZ07743.1 - 1.8e-05 24.5 0.1 3.5e-05 23.6 0.1 1.5 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 ETZ07743.1 - 0.00043 20.4 0.2 0.0023 18.0 0.2 2.2 1 1 0 1 1 1 1 Dynamin family SRPRB PF09439.10 ETZ07743.1 - 0.0017 17.9 0.0 0.0027 17.2 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 ETZ07743.1 - 0.0036 17.5 0.2 0.0069 16.6 0.2 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ETZ07743.1 - 0.024 14.2 0.1 0.37 10.4 0.0 2.1 2 0 0 2 2 2 0 Ras family GTP_EFTU PF00009.27 ETZ07743.1 - 0.027 14.0 0.1 3 7.3 0.1 2.7 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 ETZ07743.1 - 0.046 14.2 0.1 0.061 13.8 0.1 1.4 1 1 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 ETZ07743.1 - 0.059 13.9 0.0 0.077 13.5 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ETZ07743.1 - 0.07 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain YidC_periplas PF14849.6 ETZ07745.1 - 5.7e-56 190.5 0.0 7.3e-56 190.1 0.0 1.1 1 0 0 1 1 1 1 YidC periplasmic domain 60KD_IMP PF02096.20 ETZ07745.1 - 3.4e-51 173.4 8.0 5e-51 172.9 8.0 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein Ribonuclease_P PF00825.18 ETZ07746.1 - 1.3e-08 34.8 0.1 1.5e-08 34.7 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease P adh_short_C2 PF13561.6 ETZ07747.1 - 3.6e-82 275.4 0.0 4.1e-82 275.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETZ07747.1 - 3.4e-25 88.7 0.0 4.6e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETZ07747.1 - 0.043 13.7 0.1 0.09 12.7 0.0 1.5 2 0 0 2 2 2 0 KR domain Peptidase_S49 PF01343.18 ETZ07748.1 - 1.5e-52 177.7 0.0 1.9e-36 125.3 0.0 2.1 2 0 0 2 2 2 2 Peptidase family S49 CLP_protease PF00574.23 ETZ07748.1 - 4.5e-07 29.9 0.1 0.017 15.0 0.1 3.2 3 0 0 3 3 3 3 Clp protease LrgA PF03788.14 ETZ07749.1 - 0.5 10.4 11.5 5.1 7.1 0.3 2.7 2 1 0 2 2 2 0 LrgA family tRNA-synt_1b PF00579.25 ETZ07750.1 - 6.2e-56 189.9 0.0 7.3e-56 189.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF5344 PF17279.2 ETZ07750.1 - 0.097 13.3 0.0 0.6 10.7 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5344) Pribosyltran_N PF13793.6 ETZ07751.1 - 3.9e-36 123.5 0.3 3.8e-34 117.1 0.0 2.3 2 1 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 ETZ07751.1 - 4.9e-18 65.2 0.1 8.3e-18 64.4 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.6 ETZ07751.1 - 6.7e-18 65.4 2.3 6.9e-17 62.1 0.7 2.2 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain UPRTase PF14681.6 ETZ07751.1 - 2.3e-05 24.0 0.3 4.2e-05 23.1 0.1 1.5 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase DUF4392 PF14336.6 ETZ07751.1 - 0.038 13.4 0.0 0.063 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) DNA_alkylation PF08713.11 ETZ07753.1 - 3.8e-56 190.2 1.6 4.6e-56 189.9 1.6 1.0 1 0 0 1 1 1 1 DNA alkylation repair enzyme Peptidase_M41 PF01434.18 ETZ07755.1 - 7.3e-61 205.3 0.2 1.2e-60 204.7 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 ETZ07755.1 - 5.4e-45 153.0 0.0 1.5e-44 151.6 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ETZ07755.1 - 5.3e-12 45.4 0.2 5.7e-11 42.0 0.2 2.5 2 0 0 2 2 2 1 AAA+ lid domain FtsH_ext PF06480.15 ETZ07755.1 - 1.9e-09 37.8 1.4 2.2e-09 37.6 0.1 1.8 2 0 0 2 2 1 1 FtsH Extracellular AAA_5 PF07728.14 ETZ07755.1 - 2.6e-05 24.2 0.1 0.00015 21.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 ETZ07755.1 - 3.7e-05 23.1 0.0 6.8e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 ETZ07755.1 - 0.00025 20.8 0.0 0.00091 19.0 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ETZ07755.1 - 0.00041 20.6 0.1 0.045 14.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ETZ07755.1 - 0.00048 20.6 5.3 0.0095 16.3 0.2 3.4 2 2 1 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 ETZ07755.1 - 0.0026 17.9 0.0 0.0098 16.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 ETZ07755.1 - 0.0056 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 ETZ07755.1 - 0.0091 16.1 0.0 0.029 14.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 ETZ07755.1 - 0.016 14.6 0.3 0.031 13.7 0.3 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 ETZ07755.1 - 0.029 14.0 0.0 0.08 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ETZ07755.1 - 0.029 14.9 0.3 0.25 11.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 ETZ07755.1 - 0.031 14.5 0.2 0.15 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 ETZ07755.1 - 0.039 14.4 0.8 0.087 13.3 0.0 2.0 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 ETZ07755.1 - 0.042 14.2 0.0 2.2 8.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 ETZ07755.1 - 0.047 13.2 0.2 0.23 11.0 0.2 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 ETZ07755.1 - 0.059 13.4 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 ETZ07755.1 - 0.11 11.9 0.0 0.26 10.6 0.0 1.6 1 0 0 1 1 1 0 KaiC Zeta_toxin PF06414.12 ETZ07755.1 - 0.16 11.2 0.5 0.57 9.4 0.3 2.0 1 1 1 2 2 2 0 Zeta toxin SmpB PF01668.18 ETZ07756.1 - 4.6e-53 179.0 3.3 5.2e-53 178.8 3.3 1.0 1 0 0 1 1 1 1 SmpB protein DUF5537 PF17690.1 ETZ07756.1 - 0.012 15.3 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5537) SPOR PF05036.13 ETZ07756.1 - 0.081 13.3 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 Sporulation related domain RELT PF12606.8 ETZ07757.1 - 0.047 12.7 1.4 0.11 11.5 1.4 1.7 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 tRNA-synt_His PF13393.6 ETZ07759.1 - 3.1e-35 121.9 0.0 3.7e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 ETZ07759.1 - 5.9e-13 48.8 0.1 1.3e-12 47.7 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 ETZ07759.1 - 6.7e-07 29.5 0.0 1.5e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 ETZ07759.1 - 0.0081 15.3 0.1 0.053 12.6 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) ABC_tran PF00005.27 ETZ07760.1 - 2.2e-30 106.0 0.9 3.7e-30 105.2 0.9 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ETZ07760.1 - 8.3e-13 48.8 0.6 7.1e-06 26.0 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ETZ07760.1 - 5.8e-10 39.0 3.7 2.2e-08 33.8 3.7 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 ETZ07760.1 - 6.4e-07 29.4 0.6 1.2e-06 28.5 0.6 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 ETZ07760.1 - 5.4e-06 26.4 1.9 1.2e-05 25.3 1.9 1.6 1 1 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.9 ETZ07760.1 - 1.1e-05 24.5 0.5 0.029 13.2 0.0 2.1 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_23 PF13476.6 ETZ07760.1 - 0.00016 22.3 3.8 0.00073 20.1 3.6 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ETZ07760.1 - 0.00029 20.5 0.1 0.00067 19.4 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 ETZ07760.1 - 0.0005 20.4 1.3 0.0036 17.6 1.3 2.0 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 ETZ07760.1 - 0.0008 19.5 0.9 0.0015 18.6 0.9 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase T2SSE PF00437.20 ETZ07760.1 - 0.00082 18.5 0.2 0.0013 17.8 0.2 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_27 PF13514.6 ETZ07760.1 - 0.0019 17.8 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 ETZ07760.1 - 0.0024 17.6 2.2 0.59 9.8 0.3 2.3 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_5 PF07728.14 ETZ07760.1 - 0.0039 17.2 0.3 1.4 8.9 0.0 2.5 1 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ETZ07760.1 - 0.0071 16.8 0.0 0.011 16.1 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.23 ETZ07760.1 - 0.016 15.3 0.3 0.031 14.3 0.0 1.7 2 0 0 2 2 2 0 Dynamin family NTPase_1 PF03266.15 ETZ07760.1 - 0.017 15.1 0.5 4.6 7.1 0.1 2.3 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.6 ETZ07760.1 - 0.035 14.1 0.8 5.1 7.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 ETZ07760.1 - 0.036 13.8 0.1 0.087 12.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ETZ07760.1 - 0.052 13.5 0.2 0.2 11.6 0.0 1.9 2 0 0 2 2 2 0 NACHT domain Rad17 PF03215.15 ETZ07760.1 - 0.072 13.0 1.2 0.13 12.2 1.2 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 ETZ07760.1 - 0.093 12.4 0.4 0.2 11.4 0.4 1.7 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ETZ07760.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.6 ETZ07760.1 - 0.14 12.4 0.0 1.5 9.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 ETZ07760.1 - 0.26 10.4 4.2 0.46 9.6 0.5 2.4 2 1 0 2 2 2 0 NB-ARC domain KH_6 PF15985.5 ETZ07760.1 - 1 9.7 3.2 12 6.4 0.1 2.5 1 1 1 2 2 2 0 KH domain BPD_transp_2 PF02653.16 ETZ07761.1 - 1e-26 93.7 27.1 1.5e-26 93.2 27.1 1.2 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component ABC_sub_bind PF04392.12 ETZ07762.1 - 6.6e-84 281.6 10.6 7.5e-84 281.4 10.6 1.0 1 0 0 1 1 1 1 ABC transporter substrate binding protein Peripla_BP_4 PF13407.6 ETZ07762.1 - 4e-09 36.4 2.7 2.2e-05 24.1 0.8 2.1 2 0 0 2 2 2 2 Periplasmic binding protein domain ANF_receptor PF01094.28 ETZ07762.1 - 0.00084 18.5 0.6 0.67 9.0 0.0 2.1 2 0 0 2 2 2 2 Receptor family ligand binding region DUF2325 PF10087.9 ETZ07762.1 - 0.008 16.3 0.1 0.066 13.3 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2325) MAF_flag10 PF01973.18 ETZ07762.1 - 0.026 14.3 0.1 0.056 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF115 ThiF PF00899.21 ETZ07762.1 - 0.082 12.2 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 ThiF family GARS_N PF02844.15 ETZ07762.1 - 0.15 12.8 0.6 3 8.7 0.0 2.7 3 0 0 3 3 3 0 Phosphoribosylglycinamide synthetase, N domain AhpC-TSA_2 PF13911.6 ETZ07762.1 - 0.17 12.0 0.0 0.52 10.4 0.0 1.8 1 1 0 1 1 1 0 AhpC/TSA antioxidant enzyme Trp_repressor PF01371.19 ETZ07763.1 - 1.7e-20 72.9 0.0 2e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 Trp repressor protein HTH_23 PF13384.6 ETZ07763.1 - 0.00014 21.5 0.0 0.00023 20.8 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 ETZ07763.1 - 0.0002 21.1 0.1 0.00035 20.3 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain RPA_C PF08784.11 ETZ07763.1 - 0.046 14.4 0.0 0.13 13.0 0.0 1.6 2 0 0 2 2 2 0 Replication protein A C terminal NDK PF00334.19 ETZ07764.1 - 1.1e-34 119.4 0.0 1.2e-34 119.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DUF1741 PF08427.10 ETZ07764.1 - 0.19 11.4 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) DDE_Tnp_1 PF01609.21 ETZ07767.1 - 0.00017 21.3 0.0 0.00019 21.2 0.0 1.0 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 ETZ07768.1 - 0.0029 17.3 0.1 0.0029 17.3 0.1 1.0 1 0 0 1 1 1 1 Transposase DDE domain PEP-utilizers_C PF02896.18 ETZ07769.1 - 2.9e-74 249.8 0.0 4.4e-74 249.2 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.19 ETZ07769.1 - 9.1e-31 107.3 0.1 6.3e-18 65.1 0.0 3.4 1 1 2 3 3 3 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 ETZ07769.1 - 1.9e-19 69.2 0.5 3.5e-19 68.3 0.5 1.5 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain Thioredoxin_8 PF13905.6 ETZ07770.1 - 1.9e-07 31.3 0.0 3.5e-06 27.3 0.0 2.6 2 1 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 ETZ07770.1 - 5.7e-06 26.3 0.0 1.2e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.20 ETZ07770.1 - 1.3e-05 25.1 0.0 0.00019 21.4 0.0 2.3 1 1 0 2 2 2 1 Thioredoxin Redoxin PF08534.10 ETZ07770.1 - 6.2e-05 22.8 0.0 0.00042 20.1 0.0 2.0 2 0 0 2 2 2 1 Redoxin TraF PF13728.6 ETZ07770.1 - 0.0047 16.8 0.0 0.014 15.2 0.0 1.7 1 1 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 ETZ07770.1 - 0.024 14.4 0.0 0.037 13.8 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin Thioredoxin_2 PF13098.6 ETZ07770.1 - 0.098 13.1 0.0 0.32 11.5 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain LPAM_2 PF13627.6 ETZ07771.1 - 0.00036 20.3 0.4 0.00055 19.7 0.4 1.3 1 0 0 1 1 1 1 Prokaryotic lipoprotein-attachment site DUF167 PF02594.16 ETZ07774.1 - 2.1e-17 63.0 0.1 2.4e-17 62.8 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 Laminin_G_3 PF13385.6 ETZ07775.1 - 0.015 15.4 0.5 0.021 15.0 0.5 1.2 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily His_Phos_1 PF00300.22 ETZ07776.1 - 3e-11 43.4 0.1 5.9e-11 42.4 0.1 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) EAV_GP5 PF15981.5 ETZ07776.1 - 0.19 12.2 0.0 0.65 10.5 0.0 1.8 2 0 0 2 2 2 0 Envelope glycoprotein GP 5 of equine arteritis virus Imm27 PF15590.6 ETZ07777.1 - 0.12 12.2 0.1 0.13 12.0 0.1 1.1 1 0 0 1 1 1 0 Immunity protein 27 HTH_27 PF13463.6 ETZ07778.1 - 0.003 18.0 0.0 0.0049 17.3 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR_2 PF12802.7 ETZ07778.1 - 0.0059 16.5 0.1 0.014 15.3 0.0 1.7 2 0 0 2 2 2 1 MarR family MarR PF01047.22 ETZ07778.1 - 0.083 12.8 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 MarR family DUF727 PF05303.12 ETZ07778.1 - 0.1 12.7 0.0 0.13 12.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF727) SnoaL_2 PF12680.7 ETZ07780.1 - 9.5e-08 32.6 0.0 1.1e-07 32.4 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 ETZ07780.1 - 0.00022 21.6 0.0 0.00027 21.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 ETZ07780.1 - 0.0004 20.6 0.0 0.00048 20.4 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain Carboxyl_trans PF01039.22 ETZ07782.1 - 6.2e-14 51.5 0.1 1.1e-13 50.7 0.0 1.4 2 0 0 2 2 2 1 Carboxyl transferase domain zf-ACC PF17848.1 ETZ07782.1 - 2.8e-06 27.3 6.0 4.8e-06 26.5 6.0 1.4 1 0 0 1 1 1 1 Acetyl-coA carboxylase zinc finger domain HTH_Tnp_IS630 PF01710.16 ETZ07783.1 - 0.079 13.0 1.3 0.085 12.9 1.3 1.0 1 0 0 1 1 1 0 Transposase DUF3767 PF12597.8 ETZ07784.1 - 0.062 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) Asn_synthase PF00733.21 ETZ07785.1 - 1.9e-86 290.9 0.0 2.4e-86 290.6 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 ETZ07785.1 - 2.1e-38 131.0 0.0 3.3e-38 130.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 ETZ07785.1 - 9.5e-36 123.0 0.0 1.6e-35 122.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 ETZ07785.1 - 5e-08 32.7 0.0 9.8e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein DDE_Tnp_1 PF01609.21 ETZ07787.1 - 2.3e-14 53.6 0.4 2.8e-14 53.3 0.4 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 ETZ07787.1 - 1.1e-09 38.4 0.0 1.4e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 ETZ07787.1 - 2.5e-08 34.2 0.2 3.4e-08 33.8 0.2 1.2 1 0 0 1 1 1 1 Transposase DDE domain RimM PF01782.18 ETZ07788.1 - 8.1e-09 35.6 0.0 1.4e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 RimM N-terminal domain Methyltrans_RNA PF04452.14 ETZ07789.1 - 2.8e-45 154.4 0.0 3.3e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase Guanylate_kin PF00625.21 ETZ07790.1 - 3.5e-32 111.6 0.0 4.5e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.6 ETZ07790.1 - 0.00019 22.0 0.0 0.00047 20.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 ETZ07790.1 - 0.00057 20.3 0.0 0.001 19.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ETZ07790.1 - 0.0023 18.2 0.0 0.0043 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ETZ07790.1 - 0.007 16.8 0.0 0.011 16.1 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 ETZ07790.1 - 0.0077 15.5 0.0 0.0077 15.5 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain Cytidylate_kin PF02224.18 ETZ07790.1 - 0.016 14.9 0.1 0.077 12.7 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase ABC_tran PF00005.27 ETZ07790.1 - 0.019 15.5 0.0 0.028 14.9 0.0 1.2 1 0 0 1 1 1 0 ABC transporter TsaE PF02367.17 ETZ07790.1 - 0.036 14.1 0.1 0.17 11.9 0.1 2.0 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 ETZ07790.1 - 0.045 13.9 0.0 0.24 11.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ETZ07790.1 - 0.077 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 ETZ07790.1 - 0.078 13.3 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 ETZ07790.1 - 0.087 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RsgA_GTPase PF03193.16 ETZ07790.1 - 0.092 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 ETZ07790.1 - 0.1 13.0 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 ETZ07790.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Semialdhyde_dhC PF02774.18 ETZ07792.1 - 2.5e-32 112.5 0.0 3.3e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 ETZ07792.1 - 3.8e-17 62.9 0.0 1.1e-16 61.4 0.0 1.8 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 ETZ07792.1 - 0.00014 21.5 0.0 0.00025 20.7 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DXP_reductoisom PF02670.16 ETZ07792.1 - 0.0072 17.0 0.0 0.019 15.7 0.0 1.7 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Holospora_obtusa_F1-ASM46966v2/GCA_000469665.2_ASM46966v2_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Holospora_obtusa_F1-ASM46966v2/GCA_000469665.2_ASM46966v2_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Holospora_obtusa_F1-ASM46966v2/GCA_000469665.2_ASM46966v2_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Holospora_obtusa_F1-ASM46966v2/GCA_000469665.2_ASM46966v2_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 02:32:40 2019 # [ok]