# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Bac_DnaA PF00308.18 AII57224.1 - 1.8e-83 279.7 0.0 2.9e-83 279.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial dnaA protein Bac_DnaA_C PF08299.11 AII57224.1 - 1.8e-19 69.5 0.0 1.2e-18 66.9 0.0 2.4 3 0 0 3 3 3 1 Bacterial dnaA protein helix-turn-helix IstB_IS21 PF01695.17 AII57224.1 - 3.6e-09 36.6 0.0 6.9e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein DnaA_N PF11638.8 AII57224.1 - 1.3e-08 34.5 0.1 2.7e-08 33.4 0.1 1.6 1 0 0 1 1 1 1 DnaA N-terminal domain AAA PF00004.29 AII57224.1 - 0.00029 21.3 0.0 0.00076 19.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 AII57224.1 - 0.0028 17.7 0.0 0.0058 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AII57224.1 - 0.0032 17.7 0.7 1.5 9.1 0.0 3.3 2 1 1 3 3 3 1 AAA domain ATPase_2 PF01637.18 AII57224.1 - 0.032 14.2 0.0 0.068 13.1 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 AII57224.1 - 0.067 13.6 0.2 0.14 12.5 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain GTP1_OBG PF01018.22 AII57225.1 - 2.5e-56 189.6 5.9 3.7e-56 189.0 5.9 1.3 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 AII57225.1 - 1.1e-21 77.0 0.0 2.1e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AII57225.1 - 2e-12 46.9 0.0 4.4e-12 45.8 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF1967 PF09269.11 AII57225.1 - 1.4e-09 37.7 0.3 2.9e-09 36.7 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1967) RsgA_GTPase PF03193.16 AII57225.1 - 5.4e-05 23.2 0.4 0.0091 15.9 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 AII57225.1 - 0.00078 19.0 0.0 0.044 13.3 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 AII57225.1 - 0.019 15.0 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Ras PF00071.22 AII57225.1 - 0.031 13.9 0.0 4.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Ras family Arf PF00025.21 AII57225.1 - 0.073 12.5 0.1 0.19 11.2 0.1 1.8 1 1 0 1 1 1 0 ADP-ribosylation factor family CTP_transf_like PF01467.26 AII57226.1 - 2.5e-29 102.3 0.0 2.9e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like HIGH_NTase1 PF05636.11 AII57226.1 - 0.02 14.1 0.0 0.14 11.3 0.0 2.0 2 0 0 2 2 2 0 HIGH Nucleotidyl Transferase 2C_adapt PF08793.10 AII57226.1 - 0.03 14.5 0.0 2.2 8.5 0.0 2.3 2 0 0 2 2 2 0 2-cysteine adaptor domain DNA_gyraseB PF00204.25 AII57227.1 - 1.8e-58 196.9 0.0 2.9e-58 196.2 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase B DNA_gyraseB_C PF00986.21 AII57227.1 - 1.1e-28 99.2 0.0 2.5e-28 98.0 0.0 1.7 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 AII57227.1 - 2.2e-19 70.0 0.1 4.1e-19 69.1 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 AII57227.1 - 2.2e-16 60.0 0.0 5e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 Toprim domain HATPase_c_3 PF13589.6 AII57227.1 - 0.013 15.3 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HD_4 PF13328.6 AII57228.1 - 1.3e-53 180.9 0.4 2.7e-53 179.9 0.4 1.6 1 0 0 1 1 1 1 HD domain RelA_SpoT PF04607.17 AII57228.1 - 7e-38 129.5 0.0 2e-37 128.0 0.0 1.8 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins TGS PF02824.21 AII57228.1 - 1.2e-24 86.1 0.0 2.7e-24 85.0 0.0 1.6 1 0 0 1 1 1 1 TGS domain ACT_4 PF13291.6 AII57228.1 - 3.7e-20 72.3 0.4 1.3e-19 70.6 0.4 2.0 1 0 0 1 1 1 1 ACT domain HD PF01966.22 AII57228.1 - 3.2e-09 37.1 2.1 4.8e-08 33.3 0.0 3.0 3 0 0 3 3 3 1 HD domain ACT PF01842.25 AII57228.1 - 1.2e-05 24.9 0.0 3.3e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 ACT domain tRNA-synt_His PF13393.6 AII57229.1 - 1.3e-43 149.5 0.0 2.1e-43 148.8 0.0 1.4 2 0 0 2 2 2 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 AII57229.1 - 1.8e-17 63.9 0.0 3.1e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 AII57229.1 - 4.8e-10 39.5 0.0 8.4e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain zf-UDP PF14569.6 AII57229.1 - 0.13 12.4 8.8 1.4 9.1 1.1 2.9 2 1 1 3 3 3 0 Zinc-binding RING-finger Sacchrp_dh_NADP PF03435.18 AII57230.1 - 1.3e-12 48.1 0.1 2e-12 47.5 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 AII57230.1 - 2e-06 27.8 0.0 3.1e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 AII57230.1 - 0.0003 20.7 0.0 0.00054 19.9 0.0 1.5 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 AII57230.1 - 0.00071 19.7 0.1 0.0025 17.9 0.1 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 AII57230.1 - 0.00083 19.8 0.0 0.0013 19.1 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 AII57230.1 - 0.0025 17.4 0.0 0.0036 16.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 AII57230.1 - 0.013 14.9 0.0 0.027 13.9 0.0 1.5 1 1 0 1 1 1 0 short chain dehydrogenase G3P_acyltransf PF02660.15 AII57231.1 - 1.7e-39 135.5 11.5 2e-39 135.3 11.5 1.0 1 0 0 1 1 1 1 Glycerol-3-phosphate acyltransferase DUF2070 PF09843.9 AII57231.1 - 1.6 7.0 3.6 1.9 6.7 3.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Aminotran_4 PF01063.19 AII57232.1 - 5e-50 170.4 0.0 5.9e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV IMS PF00817.20 AII57233.1 - 9.3e-48 162.0 0.0 2.9e-47 160.4 0.0 1.7 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 AII57233.1 - 5.5e-18 65.8 0.1 9.2e-18 65.1 0.1 1.3 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 AII57233.1 - 8.4e-08 32.1 0.0 3.7e-07 30.1 0.0 2.2 1 0 0 1 1 1 1 IMS family HHH motif Cdd1 PF11731.8 AII57233.1 - 0.057 13.7 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Pathogenicity locus DUF1805 PF08827.11 AII57233.1 - 0.066 13.5 0.0 0.2 12.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) DUF951 PF06107.11 AII57234.1 - 6.1e-19 67.7 0.2 6.7e-19 67.5 0.2 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF951) OMPdecase PF00215.24 AII57235.1 - 9.3e-28 97.3 0.0 1.1e-27 97.1 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family DUF2807 PF10988.8 AII57236.1 - 2.5e-22 79.6 0.0 8.1e-21 74.6 0.0 2.1 1 1 0 1 1 1 1 Putative auto-transporter adhesin, head GIN domain DUF2993 PF11209.8 AII57236.1 - 0.047 13.9 0.0 0.063 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2993) DUF2807 PF10988.8 AII57237.1 - 2.7e-27 95.7 4.4 4.3e-27 95.1 4.4 1.3 1 0 0 1 1 1 1 Putative auto-transporter adhesin, head GIN domain Mur_ligase_M PF08245.12 AII57238.1 - 5e-13 49.5 0.0 8.6e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 AII57238.1 - 4.4e-05 23.6 0.0 0.00013 22.2 0.0 1.8 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain DUF3670 PF12419.8 AII57238.1 - 0.051 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 SNF2 Helicase protein TT1725 PF18324.1 AII57238.1 - 0.056 13.5 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 Hypothetical protein TT1725 FeoC PF09012.10 AII57240.1 - 0.14 12.2 0.7 0.51 10.4 0.0 2.0 2 0 0 2 2 2 0 FeoC like transcriptional regulator Tyr_Deacylase PF02580.16 AII57241.1 - 6.2e-55 185.7 0.0 7e-55 185.5 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase FUR PF01475.19 AII57242.1 - 3.2e-30 104.7 0.0 4e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Ferric uptake regulator family HTH_20 PF12840.7 AII57242.1 - 0.0067 16.5 0.0 0.0098 15.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.19 AII57242.1 - 0.011 15.5 0.0 0.061 13.2 0.0 2.2 2 1 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.20 AII57242.1 - 0.015 15.2 0.0 0.13 12.2 0.0 2.4 1 1 0 1 1 1 0 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 AII57242.1 - 0.021 14.7 0.0 0.14 12.0 0.0 2.0 1 1 0 1 1 1 0 MarR family zinc_ribbon_15 PF17032.5 AII57242.1 - 0.03 15.1 0.4 0.042 14.6 0.4 1.2 1 0 0 1 1 1 0 zinc-ribbon family Rubredoxin_2 PF18073.1 AII57242.1 - 0.069 12.9 0.6 2 8.2 0.0 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain A2L_zn_ribbon PF08792.10 AII57242.1 - 0.072 12.8 1.0 4.7 7.0 0.0 2.5 2 0 0 2 2 2 0 A2L zinc ribbon domain HTH_27 PF13463.6 AII57242.1 - 0.076 13.5 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain SR1P PF13790.6 AII57242.1 - 0.079 13.1 1.3 14 5.9 0.3 2.3 2 0 0 2 2 2 0 SR1 protein HTH_11 PF08279.12 AII57242.1 - 0.12 12.3 0.0 0.44 10.5 0.0 1.9 1 1 0 1 1 1 0 HTH domain zf_C2H2_13 PF18508.1 AII57242.1 - 0.49 10.0 2.2 1.7 8.3 0.1 2.2 2 0 0 2 2 2 0 Zinc finger domain zf-CCHC PF00098.23 AII57242.1 - 1.8 8.8 7.4 15 5.9 0.1 3.2 3 0 0 3 3 3 0 Zinc knuckle DUF5360 PF17314.2 AII57243.1 - 0.047 13.8 0.9 0.083 13.0 0.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5360) DUF2975 PF11188.8 AII57243.1 - 0.13 12.2 2.3 0.21 11.5 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) bPH_3 PF14470.6 AII57244.1 - 1.4e-05 25.3 0.0 2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial PH domain bPH_1 PF08000.11 AII57244.1 - 5.5e-05 23.2 0.1 7.6e-05 22.8 0.1 1.3 1 1 0 1 1 1 1 Bacterial PH domain Vps36_ESCRT-II PF11605.8 AII57244.1 - 0.00076 19.6 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.20 AII57244.1 - 0.0032 17.3 0.0 0.0062 16.4 0.0 1.5 1 1 0 1 1 1 1 GRAM domain Competence PF03772.16 AII57246.1 - 5.1e-57 193.2 33.3 5.1e-57 193.2 33.3 1.7 2 0 0 2 2 2 1 Competence protein DUF4131 PF13567.6 AII57246.1 - 6.1e-28 97.5 0.0 6.1e-28 97.5 0.0 4.0 3 2 0 3 3 3 1 Domain of unknown function (DUF4131) Lactamase_B PF00753.27 AII57246.1 - 1.1e-07 32.0 0.0 2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AII57246.1 - 2.6e-06 27.1 0.0 4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 AII57246.1 - 0.0066 15.9 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain DUF2628 PF10947.8 AII57246.1 - 0.13 12.6 0.1 0.13 12.6 0.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2628) HHH_3 PF12836.7 AII57247.1 - 1.3e-16 60.6 0.0 2e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix motif SLBB PF10531.9 AII57247.1 - 1.1e-06 28.4 0.0 2.1e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 SLBB domain T2SSK PF03934.13 AII57247.1 - 0.00026 20.5 0.0 0.0033 16.9 0.0 2.0 1 1 1 2 2 2 2 Type II secretion system (T2SS), protein K HHH PF00633.23 AII57247.1 - 0.0022 17.8 2.9 0.0036 17.1 0.0 2.8 4 0 0 4 4 4 1 Helix-hairpin-helix motif PsbU PF06514.11 AII57247.1 - 0.039 13.9 0.0 0.21 11.6 0.0 1.9 2 0 0 2 2 2 0 Photosystem II 12 kDa extrinsic protein (PsbU) HHH_5 PF14520.6 AII57247.1 - 0.13 12.9 0.0 2.5 8.8 0.0 2.7 3 0 0 3 3 3 0 Helix-hairpin-helix domain HHH_6 PF14579.6 AII57247.1 - 0.17 12.2 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif TrkA_N PF02254.18 AII57248.1 - 1.9e-29 102.3 0.0 3.4e-29 101.5 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain TrkA_C PF02080.21 AII57248.1 - 3.8e-10 39.4 0.4 6.5e-10 38.7 0.4 1.4 1 0 0 1 1 1 1 TrkA-C domain NAD_binding_7 PF13241.6 AII57248.1 - 6.3e-05 23.4 0.1 0.00012 22.4 0.0 1.5 2 0 0 2 2 1 1 Putative NAD(P)-binding Pyr_redox PF00070.27 AII57248.1 - 0.0007 20.1 0.0 0.0018 18.8 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 AII57248.1 - 0.0021 17.4 0.0 0.0026 17.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AII57248.1 - 0.011 16.0 0.1 0.081 13.2 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_Gly3P_dh_N PF01210.23 AII57248.1 - 0.017 15.1 0.0 0.036 14.1 0.0 1.8 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 AII57248.1 - 0.019 15.6 0.0 0.059 14.0 0.0 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 AII57248.1 - 0.022 14.4 0.1 0.04 13.6 0.1 1.5 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NmrA PF05368.13 AII57248.1 - 0.032 13.8 0.0 0.077 12.5 0.0 1.6 1 1 0 1 1 1 0 NmrA-like family UDPG_MGDP_dh_N PF03721.14 AII57248.1 - 0.057 13.0 0.5 0.21 11.1 0.5 2.0 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_zinc_N PF00107.26 AII57248.1 - 0.079 12.9 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase HI0933_like PF03486.14 AII57248.1 - 0.094 11.4 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Glyco_transf_4 PF13439.6 AII57248.1 - 0.14 12.1 0.0 9.1 6.2 0.0 2.3 1 1 1 2 2 2 0 Glycosyltransferase Family 4 TrkA_N PF02254.18 AII57249.1 - 1.1e-22 80.5 0.0 1.3e-22 80.2 0.0 1.0 1 0 0 1 1 1 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 AII57249.1 - 0.00019 21.1 0.0 0.00031 20.4 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 AII57249.1 - 0.0028 17.0 0.2 0.0033 16.7 0.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 AII57249.1 - 0.005 16.5 0.0 0.02 14.5 0.0 1.8 1 1 1 2 2 2 1 Ketopantoate reductase PanE/ApbA XdhC_C PF13478.6 AII57249.1 - 0.015 15.8 0.0 0.019 15.4 0.0 1.1 1 0 0 1 1 1 0 XdhC Rossmann domain 3HCDH_N PF02737.18 AII57249.1 - 0.016 15.1 0.1 0.019 14.9 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 AII57249.1 - 0.028 14.7 0.0 0.034 14.4 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 AII57249.1 - 0.034 13.5 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 AII57249.1 - 0.037 13.3 0.0 0.037 13.3 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.6 AII57249.1 - 0.048 14.1 0.0 0.068 13.6 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.23 AII57249.1 - 0.15 12.0 0.0 0.18 11.8 0.0 1.4 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AdoHcyase_NAD PF00670.21 AII57249.1 - 0.16 12.0 0.9 0.37 10.9 0.9 1.6 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Usp PF00582.26 AII57250.1 - 2e-19 70.5 0.2 2.2e-19 70.3 0.2 1.0 1 0 0 1 1 1 1 Universal stress protein family DAGK_cat PF00781.24 AII57250.1 - 0.16 11.6 0.2 0.25 10.9 0.2 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain TrkH PF02386.16 AII57251.1 - 3.1e-58 197.5 21.0 3.8e-56 190.6 21.0 2.2 1 1 0 1 1 1 1 Cation transport protein PsaM PF07465.13 AII57251.1 - 0.16 11.7 1.7 0.6 9.9 0.1 2.6 2 0 0 2 2 2 0 Photosystem I protein M (PsaM) TrkA_N PF02254.18 AII57252.1 - 3.6e-45 153.0 1.3 2.7e-22 79.2 0.4 2.4 2 0 0 2 2 2 2 TrkA-N domain TrkA_C PF02080.21 AII57252.1 - 1.3e-24 85.8 0.8 8.8e-11 41.5 0.1 3.1 3 0 0 3 3 3 2 TrkA-C domain NAD_binding_7 PF13241.6 AII57252.1 - 1.7e-10 41.3 0.5 1.2e-05 25.7 0.1 2.7 2 0 0 2 2 2 2 Putative NAD(P)-binding Pyr_redox PF00070.27 AII57252.1 - 1.6e-06 28.6 0.8 0.042 14.4 0.3 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 AII57252.1 - 1.8e-06 27.9 0.2 0.014 15.3 0.1 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.25 AII57252.1 - 0.00022 20.8 0.1 0.33 10.4 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase ApbA PF02558.16 AII57252.1 - 0.00053 19.7 0.2 1.4 8.5 0.1 3.1 3 0 0 3 3 3 2 Ketopantoate reductase PanE/ApbA XdhC_C PF13478.6 AII57252.1 - 0.00059 20.3 0.1 1.5 9.3 0.0 2.5 2 0 0 2 2 2 2 XdhC Rossmann domain Pyr_redox_2 PF07992.14 AII57252.1 - 0.0041 16.4 0.1 1.5 8.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 AII57252.1 - 0.0068 16.4 0.0 0.069 13.1 0.0 2.4 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_8 PF13450.6 AII57252.1 - 0.0075 16.5 0.1 6.5 7.1 0.1 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 AII57252.1 - 0.0078 15.8 0.6 0.11 12.1 0.5 2.4 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 AII57252.1 - 0.014 14.6 0.3 2 7.6 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Castor_Poll_mid PF06241.12 AII57252.1 - 0.014 15.3 0.3 2.3 8.2 0.2 2.7 2 0 0 2 2 2 0 Castor and Pollux, part of voltage-gated ion channel Trp_halogenase PF04820.14 AII57252.1 - 0.05 12.5 0.5 0.19 10.5 0.4 1.8 2 0 0 2 2 2 0 Tryptophan halogenase Epimerase PF01370.21 AII57252.1 - 0.062 12.8 0.1 2.6 7.4 0.1 2.4 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 AII57252.1 - 0.11 12.6 0.2 0.43 10.7 0.2 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase HI0933_like PF03486.14 AII57252.1 - 0.18 10.5 0.3 12 4.5 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein AlaDh_PNT_C PF01262.21 AII57252.1 - 0.31 10.3 3.0 0.65 9.3 0.4 2.4 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain PhoU_div PF01865.16 AII57254.1 - 6.4e-24 84.5 5.0 7.8e-24 84.2 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF47 FAA_hydro_N_2 PF18288.1 AII57254.1 - 0.072 13.5 0.1 7.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 E2F_TDP PF02319.20 AII57254.1 - 0.12 12.4 0.1 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 E2F/DP family winged-helix DNA-binding domain PhoU PF01895.19 AII57254.1 - 0.65 10.5 4.7 1.6 9.2 0.5 2.6 1 1 2 3 3 3 0 PhoU domain PHO4 PF01384.20 AII57255.1 - 5.6e-81 272.2 41.9 1.8e-80 270.5 41.9 1.7 1 1 0 1 1 1 1 Phosphate transporter family HTH_IclR PF09339.10 AII57255.1 - 0.0039 17.0 0.6 0.12 12.2 0.1 2.6 2 0 0 2 2 2 1 IclR helix-turn-helix domain FeoB_associated PF12669.7 AII57255.1 - 9.8 6.7 9.0 66 4.0 0.0 4.8 5 0 0 5 5 5 0 FeoB-associated Cys-rich membrane protein Guanylate_kin PF00625.21 AII57256.1 - 1.2e-38 132.6 0.0 1.4e-38 132.4 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 AII57256.1 - 0.001 19.3 0.0 0.0025 18.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AII57256.1 - 0.021 15.2 0.0 0.03 14.7 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 AII57256.1 - 0.027 15.0 0.1 0.24 12.0 0.1 2.1 1 1 0 1 1 1 0 AAA domain HflK_N PF12221.8 AII57256.1 - 0.07 13.1 0.2 0.15 12.1 0.2 1.5 1 0 0 1 1 1 0 Bacterial membrane protein N terminal AAA_22 PF13401.6 AII57256.1 - 0.11 12.7 0.0 0.34 11.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain DUF370 PF04025.12 AII57257.1 - 2.3e-31 107.7 0.1 2.8e-31 107.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF370) DHODB_Fe-S_bind PF10418.9 AII57258.1 - 2.6e-12 46.3 3.9 8.6e-12 44.7 3.9 2.0 1 0 0 1 1 1 1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B NAD_binding_1 PF00175.21 AII57258.1 - 0.04 14.6 0.0 0.087 13.5 0.0 1.6 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 AII57258.1 - 0.052 13.9 0.0 0.092 13.1 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Fer2_3 PF13085.6 AII57258.1 - 4.5 7.3 7.6 0.63 10.1 1.8 2.2 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Fer4_20 PF14691.6 AII57259.1 - 1e-43 147.7 3.0 1.7e-43 147.0 3.0 1.3 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.14 AII57259.1 - 1.3e-35 123.1 0.1 1.8e-35 122.6 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AII57259.1 - 1.9e-15 57.1 1.0 1.9e-08 34.8 0.0 2.9 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AII57259.1 - 1.9e-11 43.8 0.0 5.3e-05 22.6 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 AII57259.1 - 6.1e-09 35.5 0.0 0.0011 18.3 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 AII57259.1 - 1.6e-08 34.6 0.2 1e-07 32.0 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 AII57259.1 - 9.8e-06 25.0 1.6 2.3e-05 23.8 0.4 2.0 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 AII57259.1 - 2.1e-05 23.8 1.3 0.00024 20.3 0.3 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 AII57259.1 - 3.3e-05 23.4 5.3 0.00013 21.4 0.7 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 AII57259.1 - 3.8e-05 24.1 0.5 0.047 14.1 0.1 2.6 2 1 0 2 2 2 2 Putative NAD(P)-binding FAD_binding_2 PF00890.24 AII57259.1 - 0.00015 21.0 1.9 0.00015 21.0 1.9 2.1 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 AII57259.1 - 0.00021 20.1 0.9 0.00021 20.1 0.9 2.0 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 AII57259.1 - 0.00034 20.3 4.5 0.0028 17.3 1.0 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 AII57259.1 - 0.00065 19.0 0.1 0.00065 19.0 0.1 1.6 2 0 0 2 2 2 1 Thi4 family 2-Hacid_dh_C PF02826.19 AII57259.1 - 0.0019 17.6 0.0 0.73 9.2 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 AII57259.1 - 0.005 16.6 0.0 0.091 12.5 0.0 2.3 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Shikimate_DH PF01488.20 AII57259.1 - 0.015 15.4 0.0 2.1 8.4 0.0 2.7 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 AII57259.1 - 0.015 15.9 0.3 0.39 11.3 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Amino_oxidase PF01593.24 AII57259.1 - 0.016 14.5 0.7 0.025 13.9 0.7 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 AII57259.1 - 0.018 15.0 0.2 0.074 13.0 0.1 2.2 2 0 0 2 2 1 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 AII57259.1 - 0.022 14.6 1.2 0.72 9.7 0.7 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 AII57259.1 - 0.036 13.1 0.6 0.085 11.9 0.6 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein K_oxygenase PF13434.6 AII57259.1 - 0.039 13.1 0.0 0.63 9.1 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) ApbA PF02558.16 AII57259.1 - 0.068 12.8 0.4 0.2 11.3 0.2 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Fer4_7 PF12838.7 AII57259.1 - 0.071 13.7 0.7 0.071 13.7 0.7 2.9 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 AII57259.1 - 0.073 13.3 0.2 0.073 13.3 0.2 1.8 2 0 0 2 2 1 0 4Fe-4S dicluster domain MAF_flag10 PF01973.18 AII57259.1 - 0.084 12.6 0.1 9 6.0 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function DUF115 UDPG_MGDP_dh_N PF03721.14 AII57259.1 - 0.13 11.8 0.1 0.4 10.2 0.0 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain YjeF_N PF03853.15 AII57259.1 - 0.16 11.9 0.6 19 5.1 0.2 2.5 2 0 0 2 2 2 0 YjeF-related protein N-terminus Trp_halogenase PF04820.14 AII57259.1 - 0.38 9.6 4.4 0.078 11.8 0.7 1.6 2 0 0 2 2 2 0 Tryptophan halogenase Fer4_8 PF13183.6 AII57259.1 - 1.6 9.2 6.4 0.2 12.1 0.3 2.3 2 1 0 2 2 2 0 4Fe-4S dicluster domain SnoaL_3 PF13474.6 AII57261.1 - 4.1e-25 88.4 0.0 4.9e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 AII57261.1 - 0.0027 18.1 0.0 0.0038 17.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 AII57261.1 - 0.0043 17.7 0.0 0.006 17.2 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain CaMKII_AD PF08332.10 AII57261.1 - 0.011 15.9 0.1 0.052 13.7 0.1 1.8 1 1 0 1 1 1 0 Calcium/calmodulin dependent protein kinase II association domain Methyltransf_11 PF08241.12 AII57262.1 - 4.5e-17 62.5 0.0 7.9e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AII57262.1 - 1e-14 55.0 0.0 1.7e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AII57262.1 - 1.5e-10 40.8 0.0 5e-10 39.1 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 AII57262.1 - 2.2e-09 37.4 0.0 2.8e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AII57262.1 - 4.1e-09 36.4 0.0 4.8e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AII57262.1 - 0.0081 16.9 0.0 0.022 15.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 AII57262.1 - 0.011 15.3 0.0 0.03 13.9 0.0 1.7 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_29 PF03141.16 AII57262.1 - 0.041 12.4 0.0 0.057 12.0 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_2 PF00891.18 AII57262.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain PCMT PF01135.19 AII57262.1 - 0.13 12.0 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Imm_superinfect PF14373.6 AII57263.1 - 9.9e-20 70.2 8.6 1.4e-19 69.7 8.6 1.2 1 0 0 1 1 1 1 Superinfection immunity protein TMEM43 PF07787.12 AII57263.1 - 8.1 5.8 6.9 8.7 5.6 6.9 1.0 1 0 0 1 1 1 0 Transmembrane protein 43 Zincin_1 PF06262.11 AII57264.1 - 5e-32 109.9 0.5 6.7e-32 109.5 0.5 1.1 1 0 0 1 1 1 1 Zincin-like metallopeptidase BSP PF04450.12 AII57264.1 - 0.17 11.7 0.1 0.15 11.8 0.1 1.2 1 1 0 1 1 1 0 Peptidase of plants and bacteria Peptidase_M8 PF01457.16 AII57264.1 - 0.25 10.0 0.0 0.3 9.7 0.0 1.1 1 0 0 1 1 1 0 Leishmanolysin C_GCAxxG_C_C PF09719.10 AII57265.1 - 5.3e-26 91.2 2.0 6.1e-26 91.0 2.0 1.0 1 0 0 1 1 1 1 Putative redox-active protein (C_GCAxxG_C_C) YchF-GTPase_C PF06071.13 AII57266.1 - 3.5e-35 120.1 0.0 1.1e-34 118.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 AII57266.1 - 0.002 18.2 0.1 0.0076 16.3 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 AII57266.1 - 0.066 12.7 0.1 0.16 11.5 0.1 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.10 AII57266.1 - 0.14 11.6 1.2 0.21 11.0 0.1 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit DNA_pol3_delta PF06144.13 AII57267.1 - 1.9e-18 66.8 0.0 3e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DNA_pol3_gamma3 PF12169.8 AII57267.1 - 1.6e-05 24.8 0.2 3e-05 23.9 0.2 1.5 1 0 0 1 1 1 1 DNA polymerase III subunits gamma and tau domain III SNARE_assoc PF09335.11 AII57268.1 - 9.8e-17 61.6 7.2 9.8e-17 61.6 7.2 2.0 1 1 1 2 2 2 1 SNARE associated Golgi protein ROK PF00480.20 AII57269.1 - 1.5e-64 218.3 0.3 1.8e-64 218.1 0.3 1.0 1 0 0 1 1 1 1 ROK family FGGY_N PF00370.21 AII57269.1 - 0.019 14.5 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain tRNA-synt_2c PF01411.19 AII57270.1 - 1.7e-193 644.1 0.0 2.2e-193 643.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) DHHA1 PF02272.19 AII57270.1 - 1.1e-26 93.9 0.5 2.2e-26 92.9 0.5 1.6 1 0 0 1 1 1 1 DHHA1 domain tRNA_SAD PF07973.14 AII57270.1 - 7.3e-16 58.0 0.1 1.7e-15 56.8 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Cortex-I_coil PF09304.10 AII57270.1 - 0.18 12.0 2.9 0.53 10.5 2.9 1.7 1 0 0 1 1 1 0 Cortexillin I, coiled coil TSC22 PF01166.18 AII57270.1 - 0.41 11.0 2.0 0.9 9.9 2.0 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF1515 PF07439.11 AII57270.1 - 0.67 10.0 3.3 0.45 10.6 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) RuvX PF03652.15 AII57271.1 - 5.4e-38 130.4 0.0 6e-38 130.3 0.0 1.0 1 0 0 1 1 1 1 Holliday junction resolvase TGT PF01702.18 AII57272.1 - 8.1e-144 479.1 0.0 1e-143 478.8 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase LupA PF18242.1 AII57272.1 - 0.17 11.5 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Legionella ubiquitin-specific protease A domain Fe-ADH PF00465.19 AII57273.1 - 3.1e-99 332.3 0.0 3.4e-99 332.1 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 AII57273.1 - 1e-14 54.9 0.0 5.5e-08 32.8 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase PGM_PMM_II PF02879.16 AII57273.1 - 0.071 13.7 0.0 0.14 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II AAA_2 PF07724.14 AII57274.1 - 2e-54 184.2 0.1 1.2e-52 178.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Clp_N PF02861.20 AII57274.1 - 1.2e-37 127.8 2.4 8e-18 64.3 0.1 2.8 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_lid_9 PF17871.1 AII57274.1 - 8.2e-32 109.2 5.6 2.1e-31 107.9 5.6 1.7 1 0 0 1 1 1 1 AAA lid domain AAA PF00004.29 AII57274.1 - 1.7e-26 93.2 0.1 1.7e-14 54.4 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 AII57274.1 - 4.5e-25 87.5 0.5 1.8e-24 85.6 0.5 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 AII57274.1 - 4.4e-18 65.6 0.0 1.5e-12 47.7 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AII57274.1 - 4.1e-12 46.8 0.9 4.2e-05 24.0 0.1 4.2 2 2 2 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 AII57274.1 - 9e-10 39.0 0.3 0.0096 16.2 0.0 4.6 3 1 1 4 4 3 3 AAA domain Sigma54_activat PF00158.26 AII57274.1 - 1.9e-09 37.4 0.1 2.3e-06 27.4 0.0 2.6 2 1 0 2 2 2 2 Sigma-54 interaction domain TniB PF05621.11 AII57274.1 - 2.1e-08 33.8 0.1 1.1e-05 25.0 0.1 3.4 2 1 0 2 2 2 1 Bacterial TniB protein IstB_IS21 PF01695.17 AII57274.1 - 5.3e-07 29.5 0.0 0.0088 15.8 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 AII57274.1 - 3.1e-06 27.2 0.0 0.026 14.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 AII57274.1 - 5e-06 26.6 0.1 0.5 10.2 0.0 3.9 2 1 1 3 3 3 2 ATPase domain predominantly from Archaea AAA_18 PF13238.6 AII57274.1 - 7.7e-06 26.5 0.4 0.41 11.2 0.0 3.8 4 0 0 4 4 3 2 AAA domain Roc PF08477.13 AII57274.1 - 4e-05 23.8 0.3 0.36 11.0 0.0 3.6 4 0 0 4 4 4 2 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 AII57274.1 - 7.1e-05 22.8 0.0 0.53 10.2 0.0 2.9 3 0 0 3 3 3 2 RsgA GTPase Mg_chelatase PF01078.21 AII57274.1 - 8e-05 22.1 0.1 0.81 9.0 0.0 3.3 3 1 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 AII57274.1 - 0.00014 22.1 0.0 0.64 10.2 0.0 3.2 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 AII57274.1 - 0.00029 20.8 0.0 0.2 11.5 0.0 2.8 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 AII57274.1 - 0.00053 20.3 0.0 2.6 8.5 0.0 3.0 3 0 0 3 3 2 2 RNA helicase TsaE PF02367.17 AII57274.1 - 0.00068 19.6 0.0 1.4 8.9 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 AII57274.1 - 0.0014 18.8 0.1 2.7 8.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 AII57274.1 - 0.0017 18.9 0.1 3.2 8.3 0.0 3.1 3 0 0 3 3 2 1 ABC transporter AAA_24 PF13479.6 AII57274.1 - 0.0021 17.8 0.2 2 8.1 0.0 3.2 3 1 0 3 3 3 1 AAA domain RuvB_N PF05496.12 AII57274.1 - 0.0036 17.1 2.4 0.75 9.5 0.0 3.6 3 1 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain MMR_HSR1 PF01926.23 AII57274.1 - 0.0052 16.9 0.3 1.9 8.6 0.1 3.4 3 1 0 3 3 2 1 50S ribosome-binding GTPase AAA_3 PF07726.11 AII57274.1 - 0.0064 16.4 0.0 4.4 7.2 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 AII57274.1 - 0.0086 15.6 0.0 2.9 7.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_29 PF13555.6 AII57274.1 - 0.022 14.5 0.0 10 5.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_19 PF13245.6 AII57274.1 - 0.022 15.1 0.6 0.59 10.5 0.0 3.1 2 2 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 AII57274.1 - 0.046 13.0 0.2 4.1 6.6 0.0 3.4 3 0 0 3 3 3 0 Zeta toxin NTPase_1 PF03266.15 AII57274.1 - 0.049 13.6 0.0 3.3 7.6 0.0 3.2 2 0 0 2 2 2 0 NTPase ResIII PF04851.15 AII57274.1 - 0.059 13.4 0.1 5.2 7.0 0.0 3.3 3 1 1 4 4 3 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 AII57274.1 - 0.067 12.8 0.0 3.8 7.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 AII57274.1 - 0.087 12.6 0.1 17 5.1 0.0 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 AII57274.1 - 0.094 13.2 8.5 0.2 12.1 0.0 3.4 2 2 0 2 2 2 0 AAA domain Torsin PF06309.11 AII57274.1 - 0.12 12.5 0.0 0.93 9.6 0.0 2.2 2 0 0 2 2 2 0 Torsin ATPase PF06745.13 AII57275.1 - 3e-17 62.8 0.2 1.5e-10 40.8 0.1 2.2 2 0 0 2 2 2 2 KaiC AAA_25 PF13481.6 AII57275.1 - 2.7e-16 59.7 0.0 7e-16 58.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain Rubredoxin_2 PF18073.1 AII57275.1 - 1.4e-13 50.3 6.1 1.4e-13 50.3 5.0 1.6 2 0 0 2 2 2 1 Rubredoxin metal binding domain ChlI PF13541.6 AII57275.1 - 1.5e-09 37.7 0.1 5e-09 36.0 0.0 1.9 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase DnaB_C PF03796.15 AII57275.1 - 2.4e-06 27.1 0.0 4.7e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 AII57275.1 - 2.5e-06 28.0 0.1 6.3e-06 26.7 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain Lon_C PF05362.13 AII57275.1 - 4.7e-06 26.3 0.1 1.1e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 AII57275.1 - 2.1e-05 25.0 0.0 3.8e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad51 PF08423.11 AII57275.1 - 0.00026 20.4 0.1 0.002 17.5 0.1 2.1 1 1 0 1 1 1 1 Rad51 RecA PF00154.21 AII57275.1 - 0.0013 18.3 0.2 0.002 17.6 0.2 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_30 PF13604.6 AII57275.1 - 0.0027 17.4 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 AII57275.1 - 0.005 17.4 0.0 0.011 16.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter NTPase_1 PF03266.15 AII57275.1 - 0.0051 16.7 0.3 0.018 14.9 0.0 2.2 3 0 0 3 3 2 1 NTPase AAA_22 PF13401.6 AII57275.1 - 0.0079 16.5 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 AII57275.1 - 0.013 15.4 0.1 0.029 14.3 0.1 1.5 1 0 0 1 1 1 0 NACHT domain DAP3 PF10236.9 AII57275.1 - 0.019 14.2 0.1 0.032 13.4 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_24 PF13479.6 AII57275.1 - 0.03 14.0 0.1 0.3 10.8 0.1 2.4 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AII57275.1 - 0.035 13.4 0.2 0.069 12.4 0.2 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.14 AII57275.1 - 0.037 14.0 0.0 0.076 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 AII57275.1 - 0.05 13.6 0.0 0.091 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain zf-RING_10 PF16685.5 AII57275.1 - 0.075 13.2 0.3 0.15 12.2 0.3 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 KdpD PF02702.17 AII57275.1 - 0.077 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain Isochorismatase PF00857.20 AII57275.1 - 0.078 13.2 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Isochorismatase family TackOD1 PF18551.1 AII57275.1 - 0.088 12.5 0.2 0.14 11.8 0.2 1.3 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 IstB_IS21 PF01695.17 AII57275.1 - 0.096 12.4 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_29 PF13555.6 AII57275.1 - 0.11 12.3 0.6 1.5 8.6 0.2 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF2075 PF09848.9 AII57275.1 - 0.2 10.8 0.1 0.29 10.3 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CbiA PF01656.23 AII57275.1 - 0.24 11.5 0.8 0.95 9.5 0.3 2.2 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Zn_ribbon_SprT PF17283.2 AII57275.1 - 0.31 11.0 3.9 6.9 6.7 0.2 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain IspD PF01128.19 AII57276.1 - 2.7e-59 200.6 0.1 3e-59 200.4 0.1 1.0 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transf_3 PF12804.7 AII57276.1 - 2.5e-12 47.5 0.1 2.9e-12 47.2 0.1 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain CTP_transf_3 PF02348.19 AII57276.1 - 0.06 13.3 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase Gmx_para_CXXCG PF09535.10 AII57276.1 - 0.096 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (Gmx_para_CXXCG) NTP_transferase PF00483.23 AII57276.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase YgbB PF02542.16 AII57277.1 - 9.9e-59 198.1 0.0 1.1e-58 197.9 0.0 1.0 1 0 0 1 1 1 1 YgbB family tRNA-synt_1e PF01406.19 AII57278.1 - 2.2e-124 414.7 0.0 2.8e-124 414.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 AII57278.1 - 1e-16 60.7 0.0 1.5e-09 37.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 AII57278.1 - 1e-13 51.5 0.1 3.1e-13 50.0 0.1 1.8 1 0 0 1 1 1 1 DALR domain tRNA-synt_1 PF00133.22 AII57278.1 - 3.3e-10 38.9 0.0 4.3e-07 28.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 AII57278.1 - 2.3e-07 30.1 0.0 0.0023 16.9 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (K) HBM PF16591.5 AII57278.1 - 0.0033 16.9 0.5 0.013 15.0 0.5 1.8 2 0 0 2 2 2 1 Helical bimodular sensor domain tRNA-synt_1b PF00579.25 AII57278.1 - 0.12 11.7 0.1 15 4.8 0.0 2.7 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) DUF2067 PF09840.9 AII57278.1 - 0.12 12.0 0.0 1.5 8.3 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2067) HTH_40 PF14493.6 AII57279.1 - 0.0053 17.2 0.3 0.015 15.7 0.3 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 AII57282.1 - 5.4e-21 74.4 0.1 6.4e-21 74.2 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AII57282.1 - 3.3e-16 59.4 0.1 3.8e-16 59.2 0.1 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AII57282.1 - 2.4e-14 53.1 0.2 2.9e-14 52.8 0.2 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AII57282.1 - 6.4e-08 32.9 0.0 9e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 AII57282.1 - 4.7e-05 23.2 0.1 9.8e-05 22.1 0.1 1.6 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 AII57282.1 - 0.0016 18.2 0.8 0.22 11.3 0.1 2.2 2 0 0 2 2 2 2 Helix-turn-helix domain Phage_CI_repr PF07022.13 AII57282.1 - 0.017 15.2 0.0 0.02 15.0 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain HTH_23 PF13384.6 AII57282.1 - 0.02 14.7 0.1 1.6 8.6 0.1 2.2 2 0 0 2 2 2 0 Homeodomain-like domain HTH_24 PF13412.6 AII57282.1 - 0.042 13.4 0.1 0.19 11.3 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_37 PF13744.6 AII57282.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain RHH_1 PF01402.21 AII57282.1 - 0.11 12.4 0.4 4.2 7.5 0.2 2.4 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family cNMP_binding PF00027.29 AII57283.1 - 1.1e-21 76.6 0.0 1.8e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 AII57283.1 - 9.6e-12 44.7 0.0 2e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Crp PF00325.20 AII57283.1 - 4e-06 26.4 0.1 2.8e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 Bacterial regulatory proteins, crp family EF-hand_14 PF17959.1 AII57283.1 - 0.027 14.8 0.5 0.81 10.1 0.0 3.0 2 1 1 3 3 3 0 EF-hand domain ABC_tran_CTD PF16326.5 AII57283.1 - 0.27 11.5 0.8 0.42 10.9 0.1 1.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain Putative_PNPOx PF01243.20 AII57285.1 - 2.1e-05 24.6 0.0 3.3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase TP_methylase PF00590.20 AII57286.1 - 1.1e-31 110.4 0.0 1.7e-31 109.8 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Peripla_BP_2 PF01497.18 AII57286.1 - 1.4e-26 93.5 0.0 2e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein CbiZ PF01955.18 AII57287.1 - 2.7e-48 164.6 0.0 3.2e-48 164.4 0.0 1.1 1 0 0 1 1 1 1 Adenosylcobinamide amidohydrolase ssDBP_DBD PF18361.1 AII57287.1 - 0.18 11.9 0.1 0.65 10.1 0.0 1.8 2 0 0 2 2 2 0 Single stranded DNA-binding protein ss DNA binding domain Aminotran_5 PF00266.19 AII57288.1 - 1.5e-90 303.9 0.0 1.7e-90 303.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 AII57288.1 - 3.3e-08 33.1 0.3 5.6e-08 32.4 0.3 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 AII57288.1 - 1.6e-06 27.7 1.1 2.9e-06 26.9 1.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 AII57288.1 - 4.9e-05 22.0 0.0 7.5e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.19 AII57288.1 - 0.12 11.1 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Sdh5 PF03937.16 AII57289.1 - 0.042 13.8 0.0 0.07 13.1 0.0 1.4 1 1 0 1 1 1 0 Flavinator of succinate dehydrogenase DASH_Dad3 PF08656.10 AII57289.1 - 0.07 13.2 0.0 0.99 9.5 0.0 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad3 PE PF00934.20 AII57289.1 - 0.084 13.2 0.1 0.11 12.8 0.1 1.2 1 0 0 1 1 1 0 PE family CobD_Cbib PF03186.13 AII57290.1 - 2.9e-73 246.5 1.1 3.6e-73 246.2 1.1 1.1 1 0 0 1 1 1 1 CobD/Cbib protein Herpes_LMP1 PF05297.11 AII57290.1 - 2 7.5 5.0 3.2 6.9 5.0 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) CobA_CobO_BtuR PF02572.15 AII57291.1 - 3.2e-52 177.2 0.0 3.6e-52 177.1 0.0 1.0 1 0 0 1 1 1 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Coronavirus_5 PF05528.11 AII57291.1 - 0.056 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Coronavirus gene 5 protein Ribonuc_red_lgC PF02867.15 AII57292.1 - 5.9e-117 391.4 0.0 1.6e-115 386.6 0.0 2.1 1 1 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 AII57292.1 - 1.4e-24 85.9 0.1 3e-24 84.8 0.1 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain Radical_SAM PF04055.21 AII57293.1 - 1.3e-10 41.9 0.0 2e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AII57293.1 - 0.0094 16.2 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain CbiZ PF01955.18 AII57294.1 - 3.8e-47 160.9 0.1 4.6e-47 160.6 0.1 1.1 1 0 0 1 1 1 1 Adenosylcobinamide amidohydrolase DUF4422 PF14393.6 AII57294.1 - 0.078 12.8 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4422) Radical_SAM PF04055.21 AII57295.1 - 9.7e-05 22.8 1.2 0.0012 19.2 1.1 2.3 2 1 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 AII57295.1 - 0.0018 18.5 2.2 0.0047 17.2 2.0 1.8 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AII57295.1 - 0.051 13.7 2.8 9 6.5 2.4 2.6 2 0 0 2 2 2 0 4Fe-4S single cluster domain TP_methylase PF00590.20 AII57296.1 - 1.7e-28 100.0 0.1 1.9e-28 99.8 0.1 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Radical_SAM PF04055.21 AII57297.1 - 4.8e-13 49.8 0.2 2.9e-12 47.3 0.1 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 AII57297.1 - 0.00028 21.2 0.0 0.00047 20.4 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain DNA_pack_N PF02500.15 AII57297.1 - 0.13 12.0 0.0 0.92 9.3 0.0 2.0 2 0 0 2 2 2 0 Probable DNA packing protein, N-terminus Diphthami_syn_2 PF01902.17 AII57298.1 - 2.1e-43 148.4 0.0 2.7e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Diphthamide synthase Fer4_5 PF12801.7 AII57299.1 - 8.1e-13 48.1 13.8 8.9e-11 41.6 1.4 4.0 5 0 0 5 5 5 2 4Fe-4S binding domain FMN_bind PF04205.14 AII57299.1 - 6.1e-10 39.5 0.1 1.5e-09 38.3 0.0 1.7 2 0 0 2 2 2 1 FMN-binding domain DUF4337 PF14235.6 AII57299.1 - 0.25 11.5 0.2 0.25 11.5 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Glucos_trans_II PF14264.6 AII57300.1 - 0.047 13.1 6.2 0.054 12.8 6.2 1.1 1 0 0 1 1 1 0 Glucosyl transferase GtrII DUF4728 PF15860.5 AII57300.1 - 0.072 13.8 2.9 0.095 13.4 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4728) Tetraspanin PF00335.20 AII57300.1 - 0.13 12.0 2.8 0.14 11.8 2.8 1.2 1 0 0 1 1 1 0 Tetraspanin family TctB PF07331.11 AII57300.1 - 3.3 8.0 10.2 6 7.1 10.2 1.4 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Dehalogenase PF13486.6 AII57301.1 - 5.7e-86 288.5 0.1 7.5e-86 288.1 0.1 1.1 1 0 0 1 1 1 1 Reductive dehalogenase subunit Fer4_16 PF13484.6 AII57301.1 - 1.2e-10 42.1 7.9 1.2e-10 42.1 7.9 1.8 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 AII57301.1 - 0.00063 20.3 7.2 0.0013 19.2 7.2 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain TAT_signal PF10518.9 AII57301.1 - 0.0014 18.4 2.4 0.0014 18.4 2.4 2.0 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence Fer4 PF00037.27 AII57301.1 - 0.012 15.4 0.5 0.012 15.4 0.5 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain RLI PF04068.15 AII57301.1 - 0.12 12.2 1.6 0.13 12.1 0.1 1.9 2 0 0 2 2 2 0 Possible Fer4-like domain in RNase L inhibitor, RLI Fer4_8 PF13183.6 AII57301.1 - 0.19 12.2 3.2 2.7 8.5 1.0 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 AII57301.1 - 2.4 8.4 10.4 0.75 10.0 1.6 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain HATPase_c PF02518.26 AII57303.1 - 3.2e-26 92.0 0.0 1e-25 90.4 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1638 PF07796.11 AII57303.1 - 1.5e-08 34.9 0.0 3.7e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1638) HisKA PF00512.25 AII57303.1 - 4.1e-08 33.1 0.6 1.2e-07 31.6 0.1 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AII57303.1 - 0.01 15.8 0.0 0.061 13.2 0.0 2.3 2 0 0 2 2 2 0 GHKL domain PAS_3 PF08447.12 AII57303.1 - 0.013 15.7 0.0 0.11 12.8 0.0 2.6 2 0 0 2 2 2 0 PAS fold PAS_9 PF13426.7 AII57303.1 - 0.08 13.2 0.0 0.37 11.1 0.0 2.2 1 1 0 1 1 1 0 PAS domain COMPASS-Shg1 PF05205.12 AII57303.1 - 0.13 13.0 2.2 0.66 10.7 0.6 2.9 3 1 0 3 3 3 0 COMPASS (Complex proteins associated with Set1p) component shg1 Response_reg PF00072.24 AII57304.1 - 9.7e-26 90.1 0.0 1.5e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AII57304.1 - 3.6e-15 55.8 0.1 3.6e-15 55.8 0.1 1.9 3 0 0 3 3 3 1 Transcriptional regulatory protein, C terminal Radical_SAM PF04055.21 AII57305.1 - 3.8e-13 50.2 0.0 1.3e-12 48.5 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 AII57305.1 - 7.3e-07 29.5 0.0 1.3e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AII57305.1 - 0.017 15.2 0.3 0.057 13.5 0.3 1.9 1 1 0 1 1 1 0 4Fe-4S single cluster domain 7TMR-DISM_7TM PF07695.11 AII57306.1 - 0.0086 16.0 12.2 0.018 15.0 12.2 1.5 1 1 0 1 1 1 1 7TM diverse intracellular signalling DUF202 PF02656.15 AII57306.1 - 3.5 8.1 9.5 0.49 10.9 4.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Dehalogenase PF13486.6 AII57307.1 - 2.6e-73 246.9 0.0 3.6e-73 246.5 0.0 1.2 1 0 0 1 1 1 1 Reductive dehalogenase subunit Fer4_16 PF13484.6 AII57307.1 - 3.3e-08 34.3 5.7 9e-08 32.9 5.7 1.8 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 AII57307.1 - 2e-05 24.6 4.2 0.096 12.8 1.1 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AII57307.1 - 4.5e-05 23.5 6.9 0.0001 22.4 6.9 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain TAT_signal PF10518.9 AII57307.1 - 0.00013 21.7 2.3 0.0003 20.5 2.3 1.7 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence Fer4_7 PF12838.7 AII57307.1 - 0.00017 22.1 6.9 0.00052 20.6 6.9 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 AII57307.1 - 0.00041 20.1 15.0 0.0045 16.7 4.7 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 AII57307.1 - 0.2 12.2 8.9 0.81 10.3 8.9 2.1 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 AII57307.1 - 0.24 11.6 6.8 1.3 9.2 1.9 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 AII57307.1 - 6.6 7.3 11.8 2.4 8.7 2.6 2.4 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 AII57307.1 - 6.9 7.0 13.5 1.6 9.0 3.3 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.7 AII57307.1 - 9.5 6.5 16.7 14 6.0 3.9 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain CbiZ PF01955.18 AII57308.1 - 1.3e-48 165.6 0.6 2e-48 165.0 0.6 1.2 1 0 0 1 1 1 1 Adenosylcobinamide amidohydrolase DUF1418 PF07214.12 AII57309.1 - 0.16 11.9 0.8 0.2 11.6 0.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1418) ABC2_membrane_5 PF13346.6 AII57309.1 - 0.22 11.1 7.6 0.29 10.6 7.6 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Tetraspanin PF00335.20 AII57309.1 - 1.6 8.4 6.0 1.9 8.1 6.0 1.0 1 0 0 1 1 1 0 Tetraspanin family DUF2207 PF09972.9 AII57309.1 - 2.9 6.5 6.7 3.1 6.5 6.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Dehalogenase PF13486.6 AII57310.1 - 5.3e-90 301.7 0.1 6.6e-90 301.4 0.1 1.1 1 0 0 1 1 1 1 Reductive dehalogenase subunit Fer4_16 PF13484.6 AII57310.1 - 4.2e-11 43.6 4.4 1.1e-10 42.2 4.4 1.8 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 AII57310.1 - 0.00044 20.4 3.0 0.015 15.4 0.3 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain TAT_signal PF10518.9 AII57310.1 - 0.001 18.8 3.9 0.0022 17.8 3.9 1.6 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence Fer4_17 PF13534.6 AII57310.1 - 0.0012 19.3 1.0 0.19 12.3 0.2 2.7 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 AII57310.1 - 0.0013 19.2 0.9 0.32 11.5 0.2 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AII57310.1 - 0.0025 18.4 8.4 0.033 14.8 9.8 2.1 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4 PF00037.27 AII57310.1 - 0.0044 16.8 3.4 0.0044 16.8 3.4 2.9 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_10 PF13237.6 AII57310.1 - 0.0098 16.0 9.4 0.049 13.7 9.4 2.1 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 AII57310.1 - 0.016 15.3 4.1 0.016 15.3 4.1 2.9 3 0 0 3 3 3 0 4Fe-4S binding domain UCR_Fe-S_N PF10399.9 AII57310.1 - 0.028 13.8 0.3 0.058 12.7 0.3 1.4 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Fer4_4 PF12800.7 AII57310.1 - 0.33 11.6 11.1 0.41 11.3 1.6 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_21 PF14697.6 AII57310.1 - 0.54 10.4 4.3 1 9.5 0.6 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 AII57310.1 - 4.3 8.5 14.0 11 7.2 4.8 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Diphthami_syn_2 PF01902.17 AII57311.1 - 5.3e-39 134.0 0.1 6.5e-39 133.7 0.1 1.1 1 0 0 1 1 1 1 Diphthamide synthase ATP_bind_3 PF01171.20 AII57311.1 - 0.052 13.3 0.0 0.12 12.2 0.0 1.6 2 0 0 2 2 2 0 PP-loop family TFIIIC_delta PF12657.7 AII57311.1 - 0.11 12.4 0.2 0.33 10.9 0.2 1.8 1 1 0 1 1 1 0 Transcription factor IIIC subunit delta N-term Response_reg PF00072.24 AII57312.1 - 6.6e-26 90.7 0.8 1e-25 90.1 0.1 1.7 2 0 0 2 2 2 1 Response regulator receiver domain Trans_reg_C PF00486.28 AII57312.1 - 2.7e-15 56.2 0.0 6e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal HATPase_c PF02518.26 AII57313.1 - 1e-28 100.0 0.0 1.8e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 AII57313.1 - 1.3e-13 51.0 0.0 3.1e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AII57313.1 - 5.6e-13 49.0 0.1 1.9e-12 47.4 0.1 1.9 1 0 0 1 1 1 1 PAS domain HisKA PF00512.25 AII57313.1 - 9.4e-13 48.0 2.7 2.5e-12 46.6 0.2 2.8 3 1 1 4 4 4 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 AII57313.1 - 5e-09 36.4 0.0 9.9e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 AII57313.1 - 1.7e-08 34.5 0.0 5.7e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 PAS fold HATPase_c_3 PF13589.6 AII57313.1 - 0.00069 19.5 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AII57313.1 - 0.0012 18.8 0.0 0.0039 17.1 0.0 1.9 2 0 0 2 2 2 1 GHKL domain DUF4164 PF13747.6 AII57313.1 - 0.033 14.5 2.0 0.083 13.2 2.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) PAS_8 PF13188.7 AII57313.1 - 0.085 12.9 0.0 0.32 11.1 0.0 2.0 2 0 0 2 2 2 0 PAS domain Radical_SAM PF04055.21 AII57314.1 - 1.1e-21 77.9 0.2 2.1e-21 77.0 0.2 1.5 1 0 0 1 1 1 1 Radical SAM superfamily B12-binding PF02310.19 AII57314.1 - 4.3e-18 65.5 0.0 7.6e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 B12 binding domain Fer4_14 PF13394.6 AII57314.1 - 0.0064 16.6 0.1 0.016 15.3 0.1 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 AII57314.1 - 0.0097 16.2 0.1 0.018 15.3 0.1 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF3517 PF12030.8 AII57314.1 - 0.16 10.9 0.1 0.23 10.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3517) Radical_SAM PF04055.21 AII57315.1 - 3.8e-13 50.2 0.0 1.3e-12 48.5 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 AII57315.1 - 7.3e-07 29.5 0.0 1.3e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AII57315.1 - 0.017 15.2 0.3 0.057 13.5 0.3 1.9 1 1 0 1 1 1 0 4Fe-4S single cluster domain Diphthami_syn_2 PF01902.17 AII57316.1 - 8.2e-43 146.4 0.0 9.2e-43 146.3 0.0 1.0 1 0 0 1 1 1 1 Diphthamide synthase CutC PF03932.14 AII57316.1 - 0.095 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 CutC family ABC2_membrane_2 PF12679.7 AII57317.1 - 0.014 14.7 2.6 0.015 14.6 2.6 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF3278 PF11683.8 AII57317.1 - 0.025 14.7 0.3 0.035 14.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) DUF308 PF03729.13 AII57317.1 - 0.044 14.1 13.6 0.056 13.8 4.9 2.1 1 1 0 2 2 2 0 Short repeat of unknown function (DUF308) DUF998 PF06197.13 AII57317.1 - 0.051 13.2 6.8 0.065 12.8 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF998) EamA PF00892.20 AII57317.1 - 0.051 13.7 7.2 0.11 12.7 7.1 1.5 1 1 0 1 1 1 0 EamA-like transporter family 7TMR-DISM_7TM PF07695.11 AII57317.1 - 0.11 12.4 7.3 0.2 11.5 6.3 1.8 1 1 0 1 1 1 0 7TM diverse intracellular signalling FtsK_4TM PF13491.6 AII57317.1 - 0.12 12.1 8.7 0.13 11.9 8.7 1.0 1 0 0 1 1 1 0 4TM region of DNA translocase FtsK/SpoIIIE DUF4203 PF13886.6 AII57317.1 - 0.21 11.2 7.9 0.26 10.9 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) Meckelin PF09773.9 AII57317.1 - 0.45 8.6 0.8 0.6 8.1 0.8 1.2 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) DUF4131 PF13567.6 AII57317.1 - 2 8.1 8.0 7.7 6.1 7.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Peptidase_M48_N PF16491.5 AII57317.1 - 2 8.3 8.5 0.38 10.6 5.5 1.3 2 0 0 2 2 2 0 CAAX prenyl protease N-terminal, five membrane helices DUF4064 PF13273.6 AII57317.1 - 2.3 8.6 10.7 0.53 10.6 3.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Tetraspanin PF00335.20 AII57317.1 - 7.7 6.2 9.0 0.32 10.7 2.8 1.7 1 1 1 2 2 2 0 Tetraspanin family Dehalogenase PF13486.6 AII57318.1 - 1.6e-57 195.1 0.0 2.1e-57 194.8 0.0 1.1 1 0 0 1 1 1 1 Reductive dehalogenase subunit Fer4_16 PF13484.6 AII57318.1 - 5.7e-11 43.2 5.6 1e-10 42.4 5.6 1.4 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 AII57318.1 - 1.7e-09 38.1 6.7 3e-09 37.3 6.7 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AII57318.1 - 2.7e-07 30.6 3.5 0.0052 16.9 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 AII57318.1 - 1.2e-06 28.1 12.0 9.2e-05 22.1 4.4 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 AII57318.1 - 0.00017 22.0 5.8 0.00044 20.7 5.8 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AII57318.1 - 0.00031 20.9 10.0 0.0074 16.4 12.0 2.0 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_8 PF13183.6 AII57318.1 - 0.00034 21.0 6.3 0.00084 19.7 6.4 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 AII57318.1 - 0.00044 20.2 11.7 0.051 13.7 2.6 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain TAT_signal PF10518.9 AII57318.1 - 0.0016 18.2 2.4 0.0041 16.9 2.4 1.8 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence Fer4_21 PF14697.6 AII57318.1 - 0.012 15.7 6.7 0.47 10.6 1.0 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 AII57318.1 - 0.017 15.6 14.4 0.15 12.7 3.2 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.7 AII57318.1 - 0.36 11.0 14.3 0.089 12.9 4.6 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain CxxCxxCC PF03692.15 AII57319.1 - 1.6e-07 31.9 4.4 4.4e-07 30.5 4.4 1.7 1 1 0 1 1 1 1 Putative zinc- or iron-chelating domain PAS PF00989.25 AII57320.1 - 1.8e-09 37.6 0.0 5.9e-09 35.9 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 AII57320.1 - 1.8e-07 31.3 0.1 4.3e-07 30.1 0.1 1.7 1 0 0 1 1 1 1 PAS domain HisKA_3 PF07730.13 AII57320.1 - 5.5e-06 26.8 0.0 1.4e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase HATPase_c PF02518.26 AII57320.1 - 0.00014 22.4 0.9 0.00055 20.4 0.1 2.3 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 AII57320.1 - 0.00051 20.3 0.0 0.0023 18.2 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 AII57320.1 - 0.0012 19.0 0.0 0.0018 18.5 0.0 1.3 1 0 0 1 1 1 1 PAS fold dCache_2 PF08269.11 AII57320.1 - 0.0023 17.2 0.9 0.028 13.6 0.0 2.1 1 1 1 2 2 2 1 Cache domain PAS_11 PF14598.6 AII57320.1 - 0.0025 17.9 0.0 0.013 15.6 0.0 2.1 2 0 0 2 2 2 1 PAS domain HATPase_c_2 PF13581.6 AII57320.1 - 0.012 15.6 0.0 0.037 14.0 0.0 1.7 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain PAS_8 PF13188.7 AII57320.1 - 0.067 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 PAS domain Response_reg PF00072.24 AII57321.1 - 3.7e-18 65.7 0.0 5.9e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AII57321.1 - 9.2e-15 53.9 0.4 5.4e-13 48.3 0.1 2.3 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AII57321.1 - 0.00022 20.8 0.1 0.033 13.9 0.0 2.6 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_11 PF08279.12 AII57321.1 - 0.0038 17.1 1.2 0.0097 15.8 0.8 2.0 2 0 0 2 2 2 1 HTH domain HTH_DeoR PF08220.12 AII57321.1 - 0.023 14.4 0.1 0.039 13.7 0.1 1.4 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_23 PF13384.6 AII57321.1 - 0.03 14.1 0.0 0.1 12.4 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Mga PF08280.11 AII57321.1 - 0.046 13.7 0.2 0.15 12.1 0.2 1.9 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain MADF_DNA_bdg PF10545.9 AII57321.1 - 0.18 12.1 0.1 0.54 10.6 0.0 1.7 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Phage_integrase PF00589.22 AII57322.1 - 1.9e-36 125.4 0.0 3.7e-36 124.5 0.0 1.5 2 0 0 2 2 2 1 Phage integrase family Phage_int_SAM_4 PF13495.6 AII57322.1 - 4.3e-13 49.5 0.1 1.3e-12 48.0 0.1 1.8 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_1 PF02899.17 AII57322.1 - 5.7e-12 45.8 0.1 2e-11 44.0 0.0 2.0 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 AII57322.1 - 0.00046 20.5 0.1 0.0014 19.0 0.1 1.9 1 1 0 1 1 1 1 Phage integrase SAM-like domain Phage_int_SAM_6 PF18644.1 AII57322.1 - 0.022 14.8 0.1 0.082 12.9 0.1 1.9 1 1 0 1 1 1 0 Phage integrase SAM-like domain Rep_trans PF02486.19 AII57323.1 - 0.016 14.9 1.7 0.032 14.0 1.7 1.5 1 1 0 1 1 1 0 Replication initiation factor DNA_methylase PF00145.17 AII57324.1 - 1.2e-05 24.9 0.0 0.12 11.7 0.0 2.2 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase SSB PF00436.25 AII57325.1 - 3.9e-16 59.0 0.3 5.2e-16 58.6 0.3 1.1 1 0 0 1 1 1 1 Single-strand binding protein family ANT PF03374.14 AII57327.1 - 2.1e-06 28.0 0.0 0.032 14.6 0.0 2.5 2 0 0 2 2 2 2 Phage antirepressor protein KilAC domain ResIII PF04851.15 AII57328.1 - 7.5e-23 81.4 0.1 4.5e-22 78.8 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 AII57328.1 - 1.4e-11 44.4 0.0 3.4e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AII57328.1 - 6.6e-07 29.7 0.1 2.5e-06 27.8 0.1 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF562 PF04763.12 AII57328.1 - 0.023 14.1 0.3 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF562) INTS5_N PF14837.6 AII57328.1 - 0.025 14.2 0.1 0.051 13.2 0.1 1.5 1 0 0 1 1 1 0 Integrator complex subunit 5 N-terminus AAA_11 PF13086.6 AII57328.1 - 0.053 13.3 0.4 3.2 7.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 AII57328.1 - 0.075 13.3 0.2 0.83 9.9 0.2 2.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 AII57328.1 - 0.088 13.2 0.1 0.35 11.3 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Flavi_DEAD PF07652.14 AII57328.1 - 0.18 11.8 0.1 2.1 8.3 0.0 2.2 2 0 0 2 2 2 0 Flavivirus DEAD domain Rubrerythrin PF02915.17 AII57329.1 - 3.7e-07 30.6 2.9 4.8e-07 30.3 2.9 1.2 1 0 0 1 1 1 1 Rubrerythrin CagY_I PF14585.6 AII57329.1 - 0.084 13.0 0.1 1.7 8.8 0.1 2.4 2 1 0 2 2 2 0 CagY type 1 repeat NTP_transf_3 PF12804.7 AII57330.1 - 1.6e-29 103.3 0.0 3.6e-29 102.2 0.0 1.5 2 0 0 2 2 2 1 MobA-like NTP transferase domain NTPase_1 PF03266.15 AII57330.1 - 1.6e-22 80.2 0.0 2.6e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 NTPase DUF2478 PF10649.9 AII57330.1 - 3.5e-07 30.0 0.1 1.1e-06 28.4 0.0 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF2478) AAA_22 PF13401.6 AII57330.1 - 7.8e-05 23.0 0.0 0.00049 20.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain IspD PF01128.19 AII57330.1 - 0.028 14.1 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase AAA_18 PF13238.6 AII57330.1 - 0.056 14.0 0.0 0.12 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 AII57330.1 - 0.072 12.9 0.3 0.12 12.1 0.3 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.14 AII57330.1 - 0.17 11.9 0.0 1.6 8.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Molybdopterin PF00384.22 AII57332.1 - 8.4e-18 64.5 0.0 3.2e-17 62.6 0.0 1.9 2 1 0 2 2 2 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AII57332.1 - 4.3e-08 33.2 0.0 1.3e-07 31.6 0.0 1.8 1 1 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 AII57332.1 - 2.3e-05 24.3 0.0 7.1e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain NrfD PF03916.14 AII57333.1 - 3e-28 99.4 32.2 3e-28 99.4 32.2 1.6 2 1 0 2 2 2 1 Polysulphide reductase, NrfD Fer4_11 PF13247.6 AII57334.1 - 1.7e-22 79.4 15.4 2.2e-13 50.2 4.8 2.9 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AII57334.1 - 1.7e-15 57.3 19.0 4.6e-08 33.5 7.8 2.9 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AII57334.1 - 4.5e-12 45.9 18.3 6.5e-06 26.2 2.8 3.6 3 1 0 3 3 3 3 4Fe-4S dicluster domain Fer4_9 PF13187.6 AII57334.1 - 2.3e-09 37.2 19.5 0.00054 20.1 10.6 3.2 1 1 3 4 4 4 4 4Fe-4S dicluster domain Fer4_2 PF12797.7 AII57334.1 - 2e-07 30.7 36.8 3.5e-05 23.6 2.2 4.2 5 0 0 5 5 4 3 4Fe-4S binding domain Fer4_6 PF12837.7 AII57334.1 - 3e-07 30.2 33.2 3.4e-06 26.9 3.5 3.9 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4 PF00037.27 AII57334.1 - 4.1e-07 29.5 14.2 6.2e-06 25.8 2.9 4.5 6 0 0 6 6 4 3 4Fe-4S binding domain Fer4_8 PF13183.6 AII57334.1 - 0.00029 21.2 23.5 0.13 12.7 4.3 3.3 2 2 1 3 3 3 3 4Fe-4S dicluster domain Fer4_4 PF12800.7 AII57334.1 - 0.0015 18.9 1.7 0.0015 18.9 1.7 4.1 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_16 PF13484.6 AII57334.1 - 0.0017 19.3 20.3 0.68 10.9 0.1 3.9 3 1 0 3 3 3 3 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 AII57334.1 - 0.0045 17.1 1.7 0.0045 17.1 1.7 3.4 2 1 1 4 4 4 2 4Fe-4S dicluster domain TAT_signal PF10518.9 AII57334.1 - 0.006 16.4 1.2 0.012 15.4 0.0 2.1 3 0 0 3 3 2 1 TAT (twin-arginine translocation) pathway signal sequence Fer4_17 PF13534.6 AII57334.1 - 0.0084 16.6 24.6 0.33 11.5 2.7 3.8 2 2 3 5 5 5 2 4Fe-4S dicluster domain Fer4_15 PF13459.6 AII57334.1 - 0.011 16.5 10.2 0.012 16.3 0.3 3.1 3 0 0 3 3 3 0 4Fe-4S single cluster domain Fer4_18 PF13746.6 AII57334.1 - 0.011 16.0 9.0 0.05 13.8 2.7 2.9 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 AII57334.1 - 0.028 15.3 17.2 0.25 12.2 0.3 3.5 2 1 2 4 4 4 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 AII57334.1 - 0.18 12.8 42.7 0.14 13.2 6.8 4.3 4 0 0 4 4 4 0 4Fe-4S binding domain Fer4_13 PF13370.6 AII57334.1 - 1.4 9.5 15.1 0.3 11.6 0.5 3.2 3 0 0 3 3 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_20 PF14691.6 AII57334.1 - 1.7 8.4 22.3 0.43 10.4 3.5 3.7 3 1 1 4 4 4 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster ETF_QO PF05187.13 AII57334.1 - 2.8 8.1 10.5 16 5.7 0.8 3.2 1 1 2 3 3 3 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S ParA PF10609.9 AII57335.1 - 1.3e-84 283.6 0.3 1.6e-84 283.3 0.3 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 AII57335.1 - 2.2e-10 40.7 0.0 8.3e-10 38.8 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AII57335.1 - 3.1e-06 27.2 0.9 8.2e-05 22.6 0.9 2.2 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 AII57335.1 - 3.6e-06 26.5 0.0 6e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 ATPase MipZ FeS_assembly_P PF01883.19 AII57335.1 - 0.0015 18.7 0.0 0.004 17.3 0.0 1.8 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein ArsA_ATPase PF02374.15 AII57335.1 - 0.0034 16.6 1.7 0.0084 15.3 0.5 1.9 2 0 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.18 AII57335.1 - 0.057 12.8 0.4 0.31 10.4 0.3 2.1 3 0 0 3 3 3 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MeaB PF03308.16 AII57335.1 - 0.077 12.0 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CBP_BcsQ PF06564.12 AII57335.1 - 0.21 11.1 0.3 0.66 9.4 0.1 1.8 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ DUF2127 PF09900.9 AII57336.1 - 0.016 15.5 5.3 0.081 13.2 4.7 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2127) DegV PF02645.16 AII57337.1 - 1.5e-77 260.7 0.0 1.8e-77 260.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein, DegV family COG1307 LemA PF04011.12 AII57338.1 - 4.5e-35 120.7 0.1 7.9e-35 119.9 0.1 1.4 1 0 0 1 1 1 1 LemA family GIDE PF12483.8 AII57338.1 - 2.6e-23 82.1 0.0 4.6e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 E3 Ubiquitin ligase DUF4131 PF13567.6 AII57338.1 - 5.8 6.5 8.6 7.8 6.1 4.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Exo_endo_phos PF03372.23 AII57339.1 - 2.9e-16 59.7 0.3 4.1e-16 59.2 0.3 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 AII57339.1 - 0.0032 17.3 0.1 0.018 14.9 0.1 1.9 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase HycI PF01750.18 AII57340.1 - 1e-30 106.2 0.0 1.2e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Hydrogenase maturation protease NiFeSe_Hases PF00374.19 AII57341.1 - 3.7e-165 550.6 0.0 6.8e-165 549.8 0.0 1.4 1 1 0 1 1 1 1 Nickel-dependent hydrogenase NiFe_hyd_SSU_C PF14720.6 AII57342.1 - 2e-31 108.2 4.4 2e-31 108.1 1.3 2.1 2 0 0 2 2 2 1 NiFe/NiFeSe hydrogenase small subunit C-terminal Oxidored_q6 PF01058.22 AII57342.1 - 1.1e-30 106.1 0.4 1.9e-30 105.4 0.4 1.4 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit TAT_signal PF10518.9 AII57342.1 - 0.017 14.9 1.8 0.017 14.9 1.8 3.5 3 0 0 3 3 3 0 TAT (twin-arginine translocation) pathway signal sequence UCR_Fe-S_N PF10399.9 AII57342.1 - 0.049 13.0 0.0 0.049 13.0 0.0 3.1 3 0 0 3 3 3 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Fer4_11 PF13247.6 AII57343.1 - 2.2e-28 98.3 10.0 2.2e-28 98.3 10.0 1.8 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AII57343.1 - 1.7e-13 50.9 29.0 1.3e-07 32.1 9.0 3.3 2 1 2 4 4 4 4 4Fe-4S dicluster domain Fer4 PF00037.27 AII57343.1 - 1.1e-11 44.0 33.8 3.8e-06 26.5 1.7 5.3 6 0 0 6 6 6 4 4Fe-4S binding domain Fer4_2 PF12797.7 AII57343.1 - 2.2e-11 43.1 28.7 9.8e-05 22.2 2.0 4.4 4 0 0 4 4 4 4 4Fe-4S binding domain Fer4_6 PF12837.7 AII57343.1 - 3.4e-11 42.7 32.7 7.1e-05 22.7 2.4 4.8 4 1 0 4 4 4 3 4Fe-4S binding domain Fer4_10 PF13237.6 AII57343.1 - 6.4e-11 42.2 27.5 2.4e-05 24.3 11.1 3.5 2 1 1 3 3 3 3 4Fe-4S dicluster domain Fer4_9 PF13187.6 AII57343.1 - 4.9e-10 39.4 29.0 8.7e-06 25.8 10.0 2.6 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 AII57343.1 - 2e-05 24.6 24.9 0.00026 21.0 9.2 4.0 3 2 1 4 4 4 3 4Fe-4S dicluster domain Fer4_4 PF12800.7 AII57343.1 - 2.5e-05 24.4 39.3 0.0069 16.8 5.2 4.6 4 1 0 4 4 4 3 4Fe-4S binding domain Fer4_3 PF12798.7 AII57343.1 - 6.3e-05 23.6 40.7 0.0046 17.8 6.2 4.4 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_16 PF13484.6 AII57343.1 - 0.00013 22.9 32.5 0.27 12.2 3.9 5.2 3 1 3 6 6 6 3 4Fe-4S double cluster binding domain Fer4_8 PF13183.6 AII57343.1 - 0.00061 20.2 31.3 0.0039 17.6 8.0 3.6 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_20 PF14691.6 AII57343.1 - 0.014 15.2 2.4 0.014 15.2 2.4 3.8 2 1 1 3 3 3 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Cys_box PF17869.1 AII57343.1 - 0.13 12.4 0.6 0.13 12.4 0.6 2.8 2 1 1 3 3 2 0 Anosmin cysteine rich domain Fer4_17 PF13534.6 AII57343.1 - 0.63 10.6 31.7 17 6.1 13.2 4.4 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 AII57343.1 - 0.66 10.8 20.7 0.7 10.7 0.2 4.4 3 1 0 3 3 3 0 4Fe-4S single cluster domain ABC2_membrane_3 PF12698.7 AII57344.1 - 9.2e-34 117.1 18.1 1.1e-33 116.8 18.1 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 AII57344.1 - 3.3e-10 39.7 15.8 1.1e-09 38.1 8.5 2.5 3 0 0 3 3 3 2 ABC-2 type transporter ABC2_membrane_2 PF12679.7 AII57344.1 - 0.042 13.1 9.9 0.093 12.0 9.9 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 AII57345.1 - 2e-28 99.5 20.2 2.4e-28 99.3 20.2 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 AII57345.1 - 6.7e-11 42.0 19.8 3.6e-09 36.4 14.0 2.3 2 0 0 2 2 2 2 ABC-2 type transporter ABC2_membrane_2 PF12679.7 AII57345.1 - 3e-08 33.3 22.5 1.1e-07 31.4 22.5 1.9 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 AII57345.1 - 0.00092 19.2 12.4 0.00092 19.2 12.4 2.6 2 1 0 2 2 2 1 ABC-2 family transporter protein PspC PF04024.12 AII57345.1 - 6.9 6.6 6.7 1.4 8.8 0.5 2.6 2 0 0 2 2 2 0 PspC domain ABC_tran PF00005.27 AII57346.1 - 2.6e-30 105.7 0.0 4.3e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AII57346.1 - 1e-10 42.0 1.1 3.3e-08 33.7 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 AII57346.1 - 0.006 17.0 0.1 0.024 15.1 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF4162 PF13732.6 AII57346.1 - 0.0077 16.9 0.5 0.027 15.2 0.5 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4162) SRP54 PF00448.22 AII57346.1 - 0.064 12.9 0.2 0.13 11.9 0.2 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain GTP_EFTU PF00009.27 AII57346.1 - 0.12 11.9 0.0 3.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain SMC_N PF02463.19 AII57346.1 - 0.13 11.7 0.1 3.9 6.8 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF536 PF04394.14 AII57346.1 - 0.14 12.0 0.0 0.38 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF536 AAA_23 PF13476.6 AII57346.1 - 0.68 10.4 3.7 1.2 9.6 3.7 1.9 1 1 0 1 1 1 0 AAA domain TetR_N PF00440.23 AII57347.1 - 2.1e-08 33.8 0.0 4.3e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_17 PF17922.1 AII57347.1 - 0.00052 20.1 0.0 0.00082 19.4 0.0 1.3 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain HTH_38 PF13936.6 AII57347.1 - 0.0097 15.7 0.0 0.024 14.4 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_7 PF02796.15 AII57347.1 - 0.011 15.8 0.0 0.033 14.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase LacI PF00356.21 AII57347.1 - 0.016 15.0 0.0 0.089 12.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_11 PF08279.12 AII57347.1 - 0.021 14.8 0.0 0.054 13.4 0.0 1.7 1 0 0 1 1 1 0 HTH domain HTH_23 PF13384.6 AII57347.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain DJ-1_PfpI PF01965.24 AII57348.1 - 1.6e-39 135.4 0.0 1.9e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 AII57348.1 - 0.0046 16.7 0.0 0.017 14.8 0.0 1.8 1 1 0 2 2 2 1 ThiJ/PfpI family-like GATase_3 PF07685.14 AII57348.1 - 0.015 14.9 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain PYC_OADA PF02436.18 AII57349.1 - 1.2e-57 194.9 0.3 2.1e-57 194.1 0.3 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain HMGL-like PF00682.19 AII57349.1 - 2.8e-46 158.2 0.1 4.5e-46 157.6 0.1 1.3 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 AII57349.1 - 3e-16 59.0 7.4 8.8e-16 57.5 7.4 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.6 AII57349.1 - 2.7e-06 28.0 1.3 0.018 15.8 0.2 3.1 3 0 0 3 3 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 AII57349.1 - 3.5e-06 26.7 0.3 0.0077 16.0 0.0 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like RnfC_N PF13375.6 AII57349.1 - 4e-06 26.7 1.0 1.2e-05 25.2 1.0 1.8 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain NQRA PF05896.11 AII57349.1 - 0.00066 19.2 0.6 0.0011 18.4 0.6 1.3 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) HlyD_D23 PF16576.5 AII57349.1 - 0.00086 18.6 1.5 0.26 10.5 0.1 2.4 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion QRPTase_N PF02749.16 AII57349.1 - 0.0039 17.2 1.3 1.2 9.3 0.1 3.6 2 1 1 3 3 3 1 Quinolinate phosphoribosyl transferase, N-terminal domain GCV_H PF01597.19 AII57349.1 - 0.0056 16.6 1.1 0.0056 16.6 1.1 2.5 3 0 0 3 3 3 1 Glycine cleavage H-protein DUF2118 PF09891.9 AII57349.1 - 0.013 15.5 1.0 0.028 14.4 1.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) DUF561 PF04481.12 AII57349.1 - 0.013 14.7 0.1 0.056 12.6 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF561) TGT PF01702.18 AII57349.1 - 0.061 12.5 0.0 0.099 11.8 0.0 1.4 1 0 0 1 1 1 0 Queuine tRNA-ribosyltransferase Peptidase_M23 PF01551.22 AII57349.1 - 0.19 12.0 2.6 1.1 9.6 0.1 2.5 1 1 1 2 2 2 0 Peptidase family M23 YqfD PF06898.11 AII57349.1 - 0.22 10.3 7.2 5.1 5.8 1.2 3.1 2 1 1 3 3 3 0 Putative stage IV sporulation protein YqfD CPSase_L_D2 PF02786.17 AII57350.1 - 2.1e-76 256.1 0.2 3.5e-76 255.4 0.2 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 AII57350.1 - 1.1e-45 154.7 0.0 2.1e-45 153.8 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 AII57350.1 - 1e-40 138.2 0.0 2.1e-40 137.1 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 AII57350.1 - 4e-14 52.6 0.0 7.6e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 AII57350.1 - 1.1e-06 28.8 0.1 2.1e-06 27.9 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 AII57350.1 - 1.9e-05 24.3 0.1 4.4e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 AII57350.1 - 2.8e-05 23.8 0.0 0.00011 21.8 0.0 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 AII57350.1 - 0.002 17.7 0.0 0.011 15.4 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain 2TM PF13239.6 AII57351.1 - 2.6e-27 94.9 2.2 3e-27 94.7 2.2 1.0 1 0 0 1 1 1 1 2TM domain DUF5345 PF17280.2 AII57351.1 - 0.049 13.6 0.0 0.068 13.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5345) DUF2207 PF09972.9 AII57351.1 - 0.091 11.5 0.0 0.093 11.5 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ndc1_Nup PF09531.10 AII57351.1 - 0.12 11.1 3.7 0.14 10.8 3.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup LapA_dom PF06305.11 AII57351.1 - 0.19 11.6 0.1 0.19 11.6 0.1 1.8 2 1 1 3 3 3 0 Lipopolysaccharide assembly protein A domain Fer4_20 PF14691.6 AII57352.1 - 3.1e-19 68.8 16.2 8.5e-17 61.0 0.2 4.0 3 1 0 3 3 3 2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4 PF00037.27 AII57352.1 - 1.2e-14 53.4 13.2 4.6e-08 32.6 0.8 3.6 3 0 0 3 3 3 2 4Fe-4S binding domain Pyr_redox_2 PF07992.14 AII57352.1 - 2.9e-14 53.0 0.9 2.1e-12 46.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AII57352.1 - 2.2e-11 44.2 0.5 0.00019 21.9 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AII57352.1 - 2e-07 31.1 0.0 5.3e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Fer4_6 PF12837.7 AII57352.1 - 2.3e-07 30.6 21.6 1.1e-05 25.3 1.1 4.0 4 0 0 4 4 3 2 4Fe-4S binding domain Fer4_16 PF13484.6 AII57352.1 - 3.8e-07 31.0 20.7 7.3e-05 23.6 2.1 4.4 3 1 1 4 4 4 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 AII57352.1 - 3.9e-06 26.9 23.4 0.0025 17.9 0.3 4.0 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 AII57352.1 - 4.9e-06 26.6 0.2 4.9e-06 26.6 0.2 3.9 5 1 0 5 5 3 2 4Fe-4S dicluster domain FAD_binding_2 PF00890.24 AII57352.1 - 7.5e-06 25.3 0.2 0.00082 18.6 0.0 2.9 2 1 1 3 3 3 1 FAD binding domain Fer4_9 PF13187.6 AII57352.1 - 9.7e-06 25.7 23.3 0.0044 17.2 2.1 3.8 2 2 2 4 4 4 4 4Fe-4S dicluster domain Fer4_7 PF12838.7 AII57352.1 - 1.6e-05 25.4 27.2 0.024 15.2 2.3 3.8 2 2 1 3 3 3 3 4Fe-4S dicluster domain DAO PF01266.24 AII57352.1 - 7.8e-05 22.4 0.1 0.0041 16.8 0.0 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase Fer4_2 PF12797.7 AII57352.1 - 8e-05 22.5 27.0 0.004 17.2 2.7 4.6 4 0 0 4 4 4 2 4Fe-4S binding domain Pyr_redox_3 PF13738.6 AII57352.1 - 9.6e-05 21.8 0.4 0.014 14.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_22 PF17179.4 AII57352.1 - 0.00013 22.7 11.5 0.029 15.2 0.4 3.0 3 0 0 3 3 2 2 4Fe-4S dicluster domain HI0933_like PF03486.14 AII57352.1 - 0.0003 19.6 1.6 0.002 16.9 0.0 2.5 2 1 1 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.19 AII57352.1 - 0.0007 18.9 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 AII57352.1 - 0.0039 16.5 0.3 3.7 6.8 0.0 2.8 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 AII57352.1 - 0.02 14.1 0.2 0.045 13.0 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Fer4_15 PF13459.6 AII57352.1 - 0.021 15.6 9.5 4.3 8.2 0.2 3.5 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_4 PF12800.7 AII57352.1 - 0.021 15.3 3.7 0.021 15.3 3.7 4.4 4 0 0 4 4 4 0 4Fe-4S binding domain FAD_oxidored PF12831.7 AII57352.1 - 0.022 14.1 0.0 5.4 6.2 0.0 2.6 3 0 0 3 3 3 0 FAD dependent oxidoreductase Fer4_18 PF13746.6 AII57352.1 - 0.023 14.9 11.4 0.75 10.0 3.1 3.2 2 1 1 3 3 3 0 4Fe-4S dicluster domain NAD_binding_7 PF13241.6 AII57352.1 - 0.031 14.7 0.1 16 6.0 0.0 2.7 2 1 0 2 2 2 0 Putative NAD(P)-binding PALP PF00291.25 AII57352.1 - 0.034 13.6 0.0 4.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme 2-Hacid_dh_C PF02826.19 AII57352.1 - 0.034 13.5 0.0 0.2 11.0 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FBPase_glpX PF03320.13 AII57352.1 - 0.044 12.6 0.0 0.084 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded GIDA PF01134.22 AII57352.1 - 0.046 12.8 1.0 7.3 5.6 0.0 2.9 3 0 0 3 3 3 0 Glucose inhibited division protein A Amino_oxidase PF01593.24 AII57352.1 - 0.061 12.6 0.1 0.7 9.1 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Fer4_8 PF13183.6 AII57352.1 - 0.12 12.8 22.7 0.17 12.4 0.3 4.0 4 1 2 6 6 5 0 4Fe-4S dicluster domain ADH_N PF08240.12 AII57353.1 - 2.6e-25 88.4 1.2 5e-25 87.5 1.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 AII57353.1 - 1.1e-09 38.3 0.0 1.9e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 AII57353.1 - 5.9e-05 22.7 0.1 0.00024 20.7 0.1 1.8 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N_2 PF16884.5 AII57353.1 - 0.033 14.1 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Glycos_transf_3 PF00591.21 AII57354.1 - 9.1e-64 215.5 0.2 1.1e-63 215.1 0.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 AII57354.1 - 1.1e-14 53.9 0.1 3.1e-14 52.6 0.1 1.8 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain FMN_dh PF01070.18 AII57354.1 - 0.04 13.0 0.2 0.065 12.3 0.2 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Ntox35 PF15534.6 AII57354.1 - 0.14 12.7 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial toxin 35 PAS_9 PF13426.7 AII57355.1 - 4.4e-45 152.2 7.2 1e-12 48.2 0.4 4.8 4 0 0 4 4 4 4 PAS domain PAS PF00989.25 AII57355.1 - 7.1e-43 145.2 3.3 2e-15 56.8 0.2 4.8 4 0 0 4 4 4 4 PAS fold PAS_4 PF08448.10 AII57355.1 - 2.1e-41 140.6 0.0 2e-10 40.9 0.0 4.6 5 0 0 5 5 4 4 PAS fold PAS_3 PF08447.12 AII57355.1 - 6.4e-30 103.3 0.0 8.8e-14 51.6 0.0 4.5 4 0 0 4 4 4 4 PAS fold HATPase_c PF02518.26 AII57355.1 - 3e-23 82.5 1.0 1.1e-22 80.6 0.2 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 AII57355.1 - 1e-22 79.7 1.0 0.0002 21.3 0.0 4.9 5 0 0 5 5 5 4 PAS domain HisKA PF00512.25 AII57355.1 - 7.5e-16 57.9 3.4 5.3e-15 55.2 0.2 3.3 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 AII57355.1 - 4.9e-15 56.0 0.0 1.6e-14 54.4 0.0 1.9 2 0 0 2 2 2 1 GAF domain GAF PF01590.26 AII57355.1 - 5.3e-08 33.6 0.1 1.4e-07 32.2 0.1 1.8 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 AII57355.1 - 7.9e-07 29.5 0.0 1.8e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 GAF domain PAS_7 PF12860.7 AII57355.1 - 2.5e-06 27.6 1.0 0.12 12.6 0.1 5.4 5 0 0 5 5 5 1 PAS fold HATPase_c_5 PF14501.6 AII57355.1 - 0.00014 21.7 0.1 0.00059 19.7 0.1 2.1 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.6 AII57355.1 - 0.018 14.8 0.0 0.046 13.5 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_10 PF13596.6 AII57355.1 - 0.13 12.9 1.8 19 5.9 0.0 4.1 4 0 0 4 4 4 0 PAS domain GATase_3 PF07685.14 AII57356.1 - 1.1e-39 136.1 0.0 1.5e-39 135.7 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.23 AII57356.1 - 2.5e-16 59.9 0.0 7.5e-16 58.4 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 AII57356.1 - 4.6e-14 52.7 0.2 1.9e-07 31.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain CTP_synth_N PF06418.14 AII57356.1 - 0.0033 16.8 0.0 0.0055 16.1 0.0 1.3 1 0 0 1 1 1 1 CTP synthase N-terminus SNO PF01174.19 AII57356.1 - 0.0036 17.2 0.0 0.0065 16.3 0.0 1.3 1 0 0 1 1 1 1 SNO glutamine amidotransferase family Fer4_NifH PF00142.18 AII57356.1 - 0.028 13.9 0.0 2.6 7.4 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MobB PF03205.14 AII57356.1 - 0.037 13.9 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF1611 PF07755.11 AII57356.1 - 0.065 12.5 0.1 0.2 10.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_C) P-loop domain UPF0047 PF01894.17 AII57357.1 - 6.4e-41 139.1 0.0 7.3e-41 138.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Response_reg PF00072.24 AII57358.1 - 3e-27 95.0 0.1 3.4e-27 94.8 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain B12-binding PF02310.19 AII57358.1 - 0.023 14.7 0.0 0.028 14.5 0.0 1.1 1 0 0 1 1 1 0 B12 binding domain Rhomboid PF01694.22 AII57359.1 - 1.2e-30 106.5 17.6 1.2e-30 106.5 17.6 1.6 2 0 0 2 2 2 1 Rhomboid family DUF1751 PF08551.10 AII57359.1 - 2.2e-05 24.9 0.5 2.2e-05 24.9 0.5 1.8 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) OCD_Mu_crystall PF02423.15 AII57360.1 - 4.4e-97 324.9 0.1 4.9e-97 324.7 0.1 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 AII57360.1 - 0.073 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Zn-ribbon_8 PF09723.10 AII57361.1 - 0.011 15.8 0.3 0.019 15.0 0.3 1.5 1 0 0 1 1 1 0 Zinc ribbon domain HypA PF01155.19 AII57361.1 - 0.032 14.3 0.6 0.04 13.9 0.6 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-HYPF PF07503.12 AII57361.1 - 0.032 14.0 1.4 4.4 7.2 0.1 2.2 2 0 0 2 2 2 0 HypF finger DNA_RNApol_7kD PF03604.13 AII57361.1 - 0.063 13.0 4.2 0.86 9.3 0.2 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit ADK_lid PF05191.14 AII57361.1 - 0.076 13.0 0.9 0.22 11.5 0.9 1.8 1 1 0 1 1 1 0 Adenylate kinase, active site lid YhfH PF14149.6 AII57361.1 - 0.081 12.9 2.8 5.4 7.1 0.2 2.4 2 0 0 2 2 2 0 YhfH-like protein zf-IS66 PF13005.7 AII57361.1 - 0.2 12.1 3.3 1.4 9.4 0.3 2.2 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 zf-ribbon_3 PF13248.6 AII57361.1 - 0.22 11.0 3.4 1.5 8.4 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Nudix_N_2 PF14803.6 AII57361.1 - 0.23 11.4 4.5 1.2 9.1 0.2 2.3 2 0 0 2 2 2 0 Nudix N-terminal Zn_ribbon_SprT PF17283.2 AII57361.1 - 0.79 9.7 6.3 7.7 6.5 6.3 2.0 1 1 0 1 1 1 0 SprT-like zinc ribbon domain N_methyl PF07963.12 AII57362.1 - 8.6e-08 31.4 2.3 8.6e-08 31.4 2.3 1.7 2 0 0 2 2 2 1 Prokaryotic N-terminal methylation motif Response_reg PF00072.24 AII57363.1 - 1.9e-28 98.9 0.0 2.6e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AII57363.1 - 1.3e-26 92.5 0.0 2.3e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal HATPase_c PF02518.26 AII57364.1 - 2.6e-30 105.2 0.2 3.3e-29 101.6 0.1 2.6 3 0 0 3 3 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AII57364.1 - 1.5e-13 50.5 6.6 2.1e-13 50.1 0.1 3.5 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AII57364.1 - 2.6e-11 43.7 3.3 3.4e-11 43.3 0.2 2.9 4 0 0 4 4 4 1 HAMP domain PAS PF00989.25 AII57364.1 - 3.1e-09 36.8 0.0 8.8e-09 35.4 0.0 1.9 1 0 0 1 1 1 1 PAS fold sCache_like PF16736.5 AII57364.1 - 1.3e-06 28.4 0.0 2.5e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Single Cache-like PAS_4 PF08448.10 AII57364.1 - 1.4e-05 25.3 0.0 3.3e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 AII57364.1 - 4.1e-05 23.4 0.0 8.9e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase dCache_1 PF02743.18 AII57364.1 - 0.00041 20.2 0.0 0.013 15.4 0.0 2.2 2 0 0 2 2 2 1 Cache domain PAS_8 PF13188.7 AII57364.1 - 0.002 18.1 0.0 0.0052 16.8 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 AII57364.1 - 0.0021 18.3 0.0 0.0054 17.0 0.0 1.8 1 0 0 1 1 1 1 PAS domain HPTransfase PF10090.9 AII57364.1 - 0.027 14.3 0.0 0.059 13.2 0.0 1.6 1 0 0 1 1 1 0 Histidine phosphotransferase C-terminal domain HATPase_c_5 PF14501.6 AII57364.1 - 0.043 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 GHKL domain HATPase_c_2 PF13581.6 AII57364.1 - 0.051 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain TolA_bind_tri PF16331.5 AII57364.1 - 0.079 13.1 0.1 0.24 11.5 0.1 1.8 1 0 0 1 1 1 0 TolA binding protein trimerisation TPPK_C PF12555.8 AII57364.1 - 0.62 10.2 5.3 49 4.1 4.4 2.9 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal MGS PF02142.22 AII57365.1 - 1.3e-16 60.6 0.0 1.8e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 MGS-like domain PBP_like_2 PF12849.7 AII57366.1 - 3.7e-42 144.9 3.0 7.3e-42 144.0 3.0 1.4 1 1 0 1 1 1 1 PBP superfamily domain PBP_like PF12727.7 AII57366.1 - 7.6e-19 67.6 0.1 9.6e-19 67.3 0.1 1.1 1 0 0 1 1 1 1 PBP superfamily domain SBP_bac_11 PF13531.6 AII57366.1 - 1.1e-07 31.8 0.0 1.7e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein LysR_substrate PF03466.20 AII57366.1 - 9.7e-07 28.4 0.0 8.6e-06 25.3 0.0 2.2 1 1 0 1 1 1 1 LysR substrate binding domain SBP_bac_1 PF01547.25 AII57366.1 - 7.8e-06 26.0 0.2 1.7e-05 25.0 0.2 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 AII57366.1 - 0.0022 17.4 0.0 0.0061 16.0 0.0 1.7 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein BPD_transp_1 PF00528.22 AII57367.1 - 2.7e-25 89.2 15.9 2.7e-25 89.2 15.9 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component HlyIII PF03006.20 AII57367.1 - 0.48 10.1 4.7 0.41 10.3 1.4 2.1 2 0 0 2 2 2 0 Haemolysin-III related BPD_transp_1 PF00528.22 AII57368.1 - 5.4e-27 94.7 13.8 5.4e-27 94.7 13.8 2.2 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Orf78 PF06024.12 AII57368.1 - 2.6 8.4 4.4 1.5 9.2 0.9 2.2 2 0 0 2 2 2 0 Orf78 (ac78) ABC_tran PF00005.27 AII57369.1 - 2.3e-31 109.1 0.0 3.6e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AII57369.1 - 4.6e-11 43.1 0.1 3.8e-05 23.7 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AII57369.1 - 4.2e-10 39.4 0.0 2.2e-08 33.8 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AII57369.1 - 2.1e-07 31.7 0.1 4.2e-07 30.7 0.0 1.5 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.6 AII57369.1 - 3.4e-06 27.4 0.0 9.7e-06 25.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AII57369.1 - 3.6e-05 23.7 0.0 0.0001 22.3 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 AII57369.1 - 7.2e-05 23.2 0.0 0.00024 21.5 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AII57369.1 - 7.8e-05 22.3 0.0 0.00019 21.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 AII57369.1 - 8e-05 22.5 0.1 0.00012 22.0 0.0 1.4 2 0 0 2 2 1 1 AAA ATPase domain NB-ARC PF00931.22 AII57369.1 - 0.00022 20.5 0.0 0.00029 20.1 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain ABC_ATPase PF09818.9 AII57369.1 - 0.00024 20.0 0.0 0.068 12.0 0.0 2.1 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_18 PF13238.6 AII57369.1 - 0.00064 20.3 0.0 0.0032 18.0 0.0 2.0 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 AII57369.1 - 0.00071 19.5 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain Adeno_IVa2 PF02456.15 AII57369.1 - 0.0016 17.3 0.0 0.0051 15.7 0.0 1.7 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_28 PF13521.6 AII57369.1 - 0.0021 18.3 0.0 0.0062 16.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 AII57369.1 - 0.0071 16.5 0.0 0.013 15.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AII57369.1 - 0.014 15.1 0.0 0.067 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 AII57369.1 - 0.026 14.6 0.0 0.067 13.3 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase HAD_2 PF13419.6 AII57369.1 - 0.031 14.4 0.0 0.088 12.9 0.0 1.6 2 0 0 2 2 1 0 Haloacid dehalogenase-like hydrolase Gemin6 PF06372.12 AII57369.1 - 0.032 13.8 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Gemin6 protein ATPase PF06745.13 AII57369.1 - 0.037 13.4 0.0 0.72 9.2 0.0 2.1 2 0 0 2 2 2 0 KaiC ATPase_2 PF01637.18 AII57369.1 - 0.038 13.9 0.0 0.11 12.4 0.0 1.7 3 0 0 3 3 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 AII57369.1 - 0.042 14.3 0.0 0.45 10.9 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 AII57369.1 - 0.045 13.2 0.0 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.22 AII57369.1 - 0.061 13.7 0.1 0.33 11.4 0.0 2.1 2 0 0 2 2 2 0 RNA helicase PRK PF00485.18 AII57369.1 - 0.064 13.0 0.0 0.32 10.7 0.0 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_14 PF13173.6 AII57369.1 - 0.067 13.2 0.0 0.14 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 AII57369.1 - 0.069 12.7 0.1 0.29 10.7 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 AII57369.1 - 0.07 13.0 0.0 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 AII57369.1 - 0.089 12.4 0.0 0.26 10.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 AII57369.1 - 0.092 11.4 0.0 0.4 9.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 AII57369.1 - 0.096 12.4 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 AII57369.1 - 0.097 12.4 0.0 0.76 9.5 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_27 PF13514.6 AII57369.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_PrkA PF08298.11 AII57369.1 - 0.13 11.1 0.0 0.47 9.3 0.0 1.8 2 0 0 2 2 2 0 PrkA AAA domain TniB PF05621.11 AII57369.1 - 0.15 11.5 0.0 5.6 6.3 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA_5 PF07728.14 AII57369.1 - 0.15 12.1 0.1 0.44 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PhoU PF01895.19 AII57370.1 - 1.6e-39 134.3 9.9 9.5e-21 74.1 3.7 2.1 2 0 0 2 2 2 2 PhoU domain LMWPc PF01451.21 AII57371.1 - 5.1e-18 65.8 0.0 1.7e-17 64.1 0.0 1.7 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Acetyltransf_3 PF13302.7 AII57372.1 - 6.1e-30 104.7 0.0 7.1e-30 104.5 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AII57372.1 - 6.6e-07 29.6 0.0 7.6e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AII57372.1 - 1.1e-06 28.8 0.0 1.4e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 AII57372.1 - 0.023 14.4 0.0 0.044 13.5 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain 2Fe-2S_thioredx PF01257.19 AII57373.1 - 2.1e-45 154.2 0.0 2.3e-45 154.0 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Complex1_51K PF01512.17 AII57374.1 - 8.3e-50 168.6 0.0 1.3e-49 168.0 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 AII57374.1 - 7.8e-24 83.6 0.2 1.4e-23 82.8 0.2 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 AII57374.1 - 2.6e-09 36.8 0.0 5.9e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 SLBB domain Fe_hyd_lg_C PF02906.14 AII57375.1 - 2.7e-100 335.0 0.0 3.9e-100 334.5 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 AII57375.1 - 8.8e-21 73.7 2.8 1.5e-20 73.0 2.8 1.3 1 0 0 1 1 1 1 Iron hydrogenase small subunit Fer2_4 PF13510.6 AII57375.1 - 6.6e-20 71.0 0.5 3e-19 68.8 0.2 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 AII57375.1 - 1.5e-14 53.2 3.1 1.5e-14 53.2 3.1 2.1 2 0 0 2 2 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 AII57375.1 - 1.4e-08 34.5 0.1 1.4e-08 34.5 0.1 3.0 2 1 1 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain Fer4_21 PF14697.6 AII57375.1 - 4.8e-07 29.8 9.6 4.8e-07 29.8 9.6 2.6 3 0 0 3 3 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AII57375.1 - 1e-06 28.8 7.7 1e-06 28.8 7.7 3.3 2 1 1 3 3 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AII57375.1 - 1.5e-06 28.7 9.6 1.5e-06 28.7 9.6 3.7 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4 PF00037.27 AII57375.1 - 1.3e-05 24.8 19.7 0.00021 21.0 4.6 3.9 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_6 PF12837.7 AII57375.1 - 3.8e-05 23.6 3.3 3.8e-05 23.6 3.3 4.1 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_10 PF13237.6 AII57375.1 - 4.3e-05 23.5 5.8 0.00063 19.8 0.8 3.8 4 0 0 4 4 4 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AII57375.1 - 4.4e-05 23.8 6.1 4.4e-05 23.8 6.1 2.8 2 1 1 3 3 2 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 AII57375.1 - 0.00012 22.9 0.8 0.00012 22.9 0.8 3.7 5 0 0 5 5 3 2 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 AII57375.1 - 0.0028 17.7 3.5 0.0028 17.7 3.5 4.0 4 0 0 4 4 3 2 4Fe-4S binding domain Fer4_4 PF12800.7 AII57375.1 - 0.028 14.9 3.0 0.028 14.9 3.0 5.0 4 1 0 4 4 3 0 4Fe-4S binding domain Fer4_13 PF13370.6 AII57375.1 - 0.1 13.2 9.3 0.19 12.3 0.8 2.7 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 AII57375.1 - 0.19 12.0 12.2 0.99 9.6 1.6 2.9 1 1 0 2 2 2 0 4Fe-4S dicluster domain BCOR PF15808.5 AII57375.1 - 0.2 11.9 0.7 0.44 10.7 0.7 1.5 1 0 0 1 1 1 0 BCL-6 co-repressor, non-ankyrin-repeat region Fer4_17 PF13534.6 AII57375.1 - 3.6 8.2 20.9 1 9.9 11.8 3.4 1 1 3 4 4 4 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 AII57375.1 - 4 8.4 16.5 3.6 8.5 1.3 3.1 2 1 0 3 3 3 0 4Fe-4S dicluster domain Hydrolase_4 PF12146.8 AII57377.1 - 1e-79 267.2 0.2 1.2e-79 267.0 0.2 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AII57377.1 - 8.9e-21 74.7 1.6 2.6e-14 53.5 1.3 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AII57377.1 - 2.8e-14 54.2 0.0 3.8e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 AII57377.1 - 1.4e-07 31.4 0.9 0.0016 18.2 0.0 3.0 3 1 0 3 3 3 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 AII57377.1 - 4e-07 29.7 0.9 0.0076 15.7 0.3 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 AII57377.1 - 1.2e-05 25.2 4.4 0.075 12.8 0.2 3.1 2 1 0 3 3 3 2 Phospholipase/Carboxylesterase DLH PF01738.18 AII57377.1 - 2e-05 24.2 0.0 0.015 14.9 0.0 2.4 2 1 0 2 2 2 2 Dienelactone hydrolase family FSH1 PF03959.13 AII57377.1 - 8.9e-05 22.2 0.2 0.00034 20.3 0.2 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) PGAP1 PF07819.13 AII57377.1 - 0.00013 21.8 1.2 0.00023 21.0 1.2 1.5 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.13 AII57377.1 - 0.00086 19.2 0.0 0.0019 18.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 AII57377.1 - 0.0014 18.5 0.1 0.0024 17.8 0.1 1.4 1 0 0 1 1 1 1 Lipase (class 3) Palm_thioest PF02089.15 AII57377.1 - 0.0016 18.3 0.0 0.0036 17.2 0.0 1.6 1 1 1 2 2 2 1 Palmitoyl protein thioesterase Chlorophyllase2 PF12740.7 AII57377.1 - 0.0047 15.9 0.2 0.0077 15.2 0.2 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme PAF-AH_p_II PF03403.13 AII57377.1 - 0.025 13.1 3.3 1.9 6.9 0.3 2.9 2 1 1 3 3 3 0 Platelet-activating factor acetylhydrolase, isoform II DUF900 PF05990.12 AII57377.1 - 0.035 13.6 0.1 0.082 12.4 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Chlorophyllase PF07224.11 AII57377.1 - 0.055 12.5 0.7 0.086 11.8 0.7 1.2 1 0 0 1 1 1 0 Chlorophyllase LCAT PF02450.15 AII57377.1 - 0.058 12.6 0.0 0.089 11.9 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase LIP PF03583.14 AII57377.1 - 0.08 12.3 1.0 1.6 8.0 0.8 2.1 2 0 0 2 2 2 0 Secretory lipase DUF915 PF06028.11 AII57377.1 - 0.12 11.7 0.4 0.2 11.0 0.4 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.20 AII57377.1 - 0.12 12.4 0.4 0.21 11.7 0.4 1.4 1 0 0 1 1 1 0 Thioesterase domain LIDHydrolase PF10230.9 AII57377.1 - 0.14 11.7 1.2 0.71 9.4 1.1 2.0 1 1 1 2 2 2 0 Lipid-droplet associated hydrolase DUF676 PF05057.14 AII57377.1 - 0.15 11.6 0.6 0.23 10.9 0.1 1.7 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Esterase PF00756.20 AII57377.1 - 0.17 11.5 0.2 0.31 10.6 0.2 1.4 1 1 0 1 1 1 0 Putative esterase DUF45 PF01863.17 AII57379.1 - 1.9e-57 194.7 0.2 2.6e-57 194.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF45 WLM PF08325.10 AII57379.1 - 0.022 14.8 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 WLM domain Peptidase_M57 PF12388.8 AII57379.1 - 0.041 13.5 0.0 0.067 12.8 0.0 1.2 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Reprolysin_3 PF13582.6 AII57379.1 - 0.11 13.1 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4570 PF15134.6 AII57379.1 - 0.16 12.0 0.3 0.46 10.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) EamA PF00892.20 AII57380.1 - 1.3e-35 122.5 36.9 3.2e-18 66.2 13.2 2.0 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 AII57380.1 - 6.5e-05 22.4 12.3 0.00016 21.1 12.3 1.6 1 1 0 1 1 1 1 Triose-phosphate Transporter family PUNUT PF16913.5 AII57380.1 - 0.00023 20.5 2.9 0.00054 19.3 2.9 1.6 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport UAA PF08449.11 AII57380.1 - 0.0011 18.2 2.3 0.0011 18.2 2.3 2.2 2 0 0 2 2 2 1 UAA transporter family UPF0060 PF02694.15 AII57380.1 - 0.087 13.1 6.1 1.9 8.8 0.9 2.9 2 1 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family SLC35F PF06027.12 AII57380.1 - 0.12 11.8 10.9 0.74 9.3 11.1 2.1 1 1 0 1 1 1 0 Solute carrier family 35 Beta_elim_lyase PF01212.21 AII57381.1 - 1.9e-91 306.4 0.0 2.3e-91 306.1 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 AII57381.1 - 2e-06 27.3 0.0 4.7e-06 26.0 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 AII57381.1 - 6.1e-06 25.8 0.0 0.0057 16.0 0.0 2.2 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 AII57381.1 - 0.0018 16.9 0.0 0.0041 15.7 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme CMD PF02627.20 AII57382.1 - 3.6e-08 33.3 0.0 5.6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Resolvase PF00239.21 AII57383.1 - 1.7e-34 119.0 0.2 3.7e-34 117.9 0.2 1.6 1 0 0 1 1 1 1 Resolvase, N terminal domain Recombinase PF07508.13 AII57383.1 - 1.7e-21 76.6 0.0 5e-21 75.0 0.0 1.9 1 0 0 1 1 1 1 Recombinase Zn_ribbon_recom PF13408.6 AII57383.1 - 2.5e-12 47.1 1.0 4.9e-12 46.2 1.0 1.5 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain RNA_lig_T4_1 PF09511.10 AII57383.1 - 0.022 14.6 0.2 0.066 13.1 0.1 2.0 2 0 0 2 2 2 0 RNA ligase zinc_ribbon_2 PF13240.6 AII57383.1 - 0.51 10.1 3.1 5.7 6.8 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Peptidase_M78 PF06114.13 AII57384.1 - 0.00013 21.9 0.0 0.00027 20.9 0.0 1.5 1 1 0 1 1 1 1 IrrE N-terminal-like domain TCRP1 PF14944.6 AII57384.1 - 0.1 12.5 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Tongue Cancer Chemotherapy Resistant Protein 1 HTH_31 PF13560.6 AII57385.1 - 4.3e-18 65.4 0.0 6.6e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 AII57385.1 - 3.5e-17 62.2 0.1 5.4e-17 61.6 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 AII57385.1 - 1e-14 54.3 0.0 1.5e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 AII57385.1 - 2.4e-08 33.7 0.0 3.5e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AII57385.1 - 3.8e-05 24.0 0.0 5.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_37 PF13744.6 AII57385.1 - 0.0012 18.8 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 AII57385.1 - 0.078 12.5 0.1 0.2 11.2 0.1 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_15 PF12324.8 AII57385.1 - 0.11 12.5 0.0 5.8 7.0 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase DUF3854 PF12965.7 AII57387.1 - 4.5e-23 81.7 0.0 9.5e-23 80.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3854) HTH_15 PF12324.8 AII57387.1 - 0.013 15.4 0.0 0.04 13.9 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase ThrE PF06738.12 AII57388.1 - 0.053 12.9 0.1 0.062 12.7 0.1 1.0 1 0 0 1 1 1 0 Putative threonine/serine exporter DUF3120 PF11318.8 AII57388.1 - 0.067 13.5 2.8 0.078 13.3 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) DUF4191 PF13829.6 AII57388.1 - 0.13 11.6 0.2 0.13 11.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DnaJ PF00226.31 AII57389.1 - 7.4e-13 48.4 0.0 9.4e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 DnaJ domain MCM PF00493.23 AII57390.1 - 1.9e-10 40.2 0.0 0.0017 17.5 0.0 3.5 2 1 1 3 3 3 2 MCM P-loop domain AAA PF00004.29 AII57390.1 - 4.2e-09 36.9 0.1 1.7e-08 35.0 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AII57390.1 - 6.6e-08 32.6 0.4 3.3e-07 30.4 0.1 1.9 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 AII57390.1 - 7.5e-07 29.0 0.0 1.3e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 AII57390.1 - 0.0014 18.8 0.0 0.0031 17.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_3 PF07726.11 AII57390.1 - 0.003 17.4 0.1 0.15 11.9 0.0 2.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 AII57390.1 - 0.013 15.8 0.1 0.25 11.7 0.1 2.5 1 1 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 AII57390.1 - 0.07 12.8 0.0 0.32 10.7 0.0 1.9 1 1 1 2 2 2 0 Sigma-54 interaction domain AAA_22 PF13401.6 AII57390.1 - 0.082 13.2 0.3 0.81 10.0 0.1 2.4 2 1 1 3 3 3 0 AAA domain HTH_11 PF08279.12 AII57391.1 - 0.0037 17.2 0.6 0.011 15.6 0.1 2.0 2 0 0 2 2 2 1 HTH domain HTH_23 PF13384.6 AII57391.1 - 0.0052 16.5 0.5 0.03 14.1 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain GntR PF00392.21 AII57391.1 - 0.01 15.5 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_7 PF02796.15 AII57391.1 - 0.01 15.9 0.0 0.033 14.2 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_IclR PF09339.10 AII57391.1 - 0.01 15.6 0.7 0.14 12.0 0.0 2.7 3 0 0 3 3 3 0 IclR helix-turn-helix domain Sigma70_r4_2 PF08281.12 AII57391.1 - 0.012 15.2 0.2 0.062 13.0 0.0 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 PDCD7 PF16021.5 AII57391.1 - 0.023 13.8 0.4 0.023 13.8 0.4 2.4 1 1 1 2 2 2 0 Programmed cell death protein 7 YbjQ_1 PF01906.17 AII57391.1 - 0.03 15.0 0.0 0.074 13.7 0.0 1.7 1 0 0 1 1 1 0 Putative heavy-metal-binding GcrA PF07750.11 AII57391.1 - 0.083 13.3 0.2 0.083 13.3 0.2 2.2 1 1 1 2 2 2 0 GcrA cell cycle regulator HTH_24 PF13412.6 AII57391.1 - 0.096 12.3 0.7 0.26 10.9 0.1 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding SpoIIID PF12116.8 AII57391.1 - 0.12 12.5 0.8 0.27 11.4 0.1 1.9 2 0 0 2 2 2 0 Stage III sporulation protein D TrmB PF01978.19 AII57391.1 - 0.14 12.1 0.1 0.73 9.8 0.0 2.2 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 AII57391.1 - 0.27 11.2 3.8 0.25 11.4 0.3 2.6 3 0 0 3 3 3 0 Crp-like helix-turn-helix domain Rotamase PF00639.21 AII57391.1 - 0.39 11.7 3.1 1.6 9.7 0.7 2.5 3 0 0 3 3 2 0 PPIC-type PPIASE domain DUF2232 PF09991.9 AII57391.1 - 0.46 9.6 1.7 0.71 9.0 1.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) SCAB_CC PF16712.5 AII57392.1 - 0.003 17.4 0.2 0.0035 17.2 0.2 1.1 1 0 0 1 1 1 1 Coiled-coil regions of plant-specific actin-binding protein MazE_antitoxin PF04014.18 AII57394.1 - 3.6e-09 36.3 0.1 5.3e-09 35.8 0.1 1.2 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin DUF1905 PF08922.11 AII57394.1 - 0.031 14.4 0.0 0.043 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1905) DUF3671 PF12420.8 AII57397.1 - 0.082 13.0 0.1 0.087 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function Corona_RPol_N PF06478.13 AII57397.1 - 0.63 9.0 2.5 0.66 8.9 2.5 1.1 1 0 0 1 1 1 0 Coronavirus RPol N-terminus DUF1385 PF07136.11 AII57399.1 - 0.024 14.0 0.2 0.026 13.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) DUF2207 PF09972.9 AII57399.1 - 0.11 11.3 0.5 0.14 10.9 0.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Peptidase_S8 PF00082.22 AII57405.1 - 2.4e-35 122.3 0.2 4.3e-35 121.4 0.2 1.4 1 1 0 1 1 1 1 Subtilase family ATP-synt_I PF03899.15 AII57406.1 - 0.18 12.2 3.4 0.82 10.1 3.4 1.9 1 1 0 1 1 1 0 ATP synthase I chain DUF11 PF01345.18 AII57407.1 - 0.086 13.1 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF11 Pro_Al_protease PF02983.14 AII57408.1 - 0.04 14.0 0.0 0.082 13.0 0.0 1.5 1 0 0 1 1 1 0 Alpha-lytic protease prodomain OCRE PF17780.1 AII57408.1 - 0.047 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 OCRE domain Phage_integrase PF00589.22 AII57410.1 - 7.7e-27 94.2 0.1 1.4e-26 93.3 0.1 1.4 1 1 0 1 1 1 1 Phage integrase family DZR PF12773.7 AII57410.1 - 6.2e-05 22.9 0.5 0.00013 21.9 0.5 1.5 1 0 0 1 1 1 1 Double zinc ribbon zf-NADH-PPase PF09297.11 AII57410.1 - 0.0001 21.9 0.9 0.004 16.8 0.0 2.6 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.6 AII57410.1 - 0.00053 19.6 4.7 0.00053 19.6 4.7 1.8 2 0 0 2 2 2 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 AII57410.1 - 0.00067 19.0 2.4 0.00067 19.0 2.4 1.6 2 0 0 2 2 1 1 zinc-ribbon domain DNA_ligase_ZBD PF03119.16 AII57410.1 - 0.00087 19.3 2.5 0.022 14.8 0.2 2.5 2 0 0 2 2 2 1 NAD-dependent DNA ligase C4 zinc finger domain Nudix_N_2 PF14803.6 AII57410.1 - 0.0011 18.9 3.6 0.0016 18.3 0.2 2.7 3 0 0 3 3 3 1 Nudix N-terminal zf-C3HC4_3 PF13920.6 AII57410.1 - 0.0046 16.8 1.3 0.0082 16.0 1.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_15 PF17032.5 AII57410.1 - 0.0047 17.7 0.1 0.0082 16.9 0.1 1.5 1 0 0 1 1 1 1 zinc-ribbon family zinc-ribbons_6 PF07191.12 AII57410.1 - 0.0078 16.2 0.6 0.017 15.1 0.6 1.5 1 0 0 1 1 1 1 zinc-ribbons HypA PF01155.19 AII57410.1 - 0.016 15.2 0.2 0.14 12.2 0.2 2.1 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 AII57410.1 - 0.056 13.6 3.7 1.6 9.0 0.2 2.5 1 1 1 2 2 2 0 Zinc ribbon domain zf-LITAF-like PF10601.9 AII57410.1 - 0.07 13.4 1.8 1.7 9.0 0.1 2.5 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain zf-IS66 PF13005.7 AII57410.1 - 0.081 13.3 1.1 8.3 6.9 0.1 2.6 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 TF_Zn_Ribbon PF08271.12 AII57410.1 - 0.1 12.1 2.6 0.39 10.3 2.6 2.0 1 1 0 1 1 1 0 TFIIB zinc-binding zf_UBZ PF18439.1 AII57410.1 - 0.27 10.9 2.1 8.1 6.1 0.2 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger UPF0547 PF10571.9 AII57410.1 - 0.3 11.2 3.9 0.61 10.2 3.9 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-Di19 PF05605.12 AII57410.1 - 0.34 11.2 2.3 8.4 6.8 0.2 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-ISL3 PF14690.6 AII57410.1 - 0.6 10.8 4.2 2.8 8.7 0.2 2.8 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-dskA_traR PF01258.17 AII57410.1 - 1.4 8.9 4.2 22 5.1 0.0 2.7 3 0 0 3 3 2 0 Prokaryotic dksA/traR C4-type zinc finger DUF192 PF02643.15 AII57412.1 - 2.4e-15 56.4 0.0 4.4e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized ACR, COG1430 DUF1738 PF08401.11 AII57412.1 - 0.00058 20.0 0.0 0.001 19.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1738) Peptidase_M78 PF06114.13 AII57412.1 - 0.0082 16.1 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 IrrE N-terminal-like domain AAA_15 PF13175.6 AII57414.1 - 6.7e-33 114.9 0.0 2.1e-15 57.4 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 AII57414.1 - 2.8e-19 70.1 1.8 2.7e-12 47.1 1.1 2.4 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF2813 PF11398.8 AII57414.1 - 1.6e-18 67.2 1.0 1.2e-13 51.1 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2813) SMC_N PF02463.19 AII57414.1 - 3.7e-07 29.8 0.0 7.8e-07 28.8 0.0 1.5 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AII57414.1 - 4.1e-06 27.4 0.0 9.5e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AII57414.1 - 0.00014 21.5 0.0 0.00026 20.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 AII57414.1 - 0.0077 16.7 0.0 0.019 15.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 AII57414.1 - 0.12 12.4 0.0 0.36 10.9 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_ATPase PF09818.9 AII57414.1 - 0.18 10.6 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class RNA_helicase PF00910.22 AII57414.1 - 0.22 11.9 0.0 0.61 10.5 0.0 1.7 2 0 0 2 2 2 0 RNA helicase DNA_pol3_beta_3 PF02768.15 AII57416.1 - 5.4e-09 35.9 0.0 5.3e-08 32.7 0.0 2.4 2 0 0 2 2 2 1 DNA polymerase III beta subunit, C-terminal domain DNA_pol3_beta_2 PF02767.16 AII57416.1 - 2.9e-07 30.7 0.0 8.8e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase III beta subunit, central domain DNA_pol3_beta PF00712.19 AII57416.1 - 4.7e-06 26.7 0.0 0.0012 19.0 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase III beta subunit, N-terminal domain DUF1819 PF08849.11 AII57421.1 - 0.1 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) DUF1788 PF08747.11 AII57422.1 - 3.3e-09 36.8 0.0 7.1e-09 35.7 0.0 1.5 1 1 1 2 2 2 1 Domain of unknown function (DUF1788) GP3_package PF16677.5 AII57422.1 - 0.022 14.9 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 DNA-packaging protein gp3 AAA_16 PF13191.6 AII57423.1 - 7.6e-05 23.2 0.2 7.6e-05 23.2 0.2 4.4 3 1 1 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 AII57423.1 - 0.0042 17.4 0.2 5.4 7.3 0.0 3.9 3 0 0 3 3 3 1 AAA domain CysG_dimeriser PF10414.9 AII57423.1 - 0.013 15.2 3.8 0.2 11.4 0.1 3.9 3 0 0 3 3 3 0 Sirohaem synthase dimerisation region DUF2791 PF10923.8 AII57423.1 - 0.045 12.6 0.0 0.11 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) KAP_NTPase PF07693.14 AII57423.1 - 0.075 12.3 0.1 0.41 9.8 0.0 2.1 2 0 0 2 2 2 0 KAP family P-loop domain YbaB_DNA_bd PF02575.16 AII57423.1 - 0.16 12.2 1.7 5.2 7.4 0.0 3.4 3 0 0 3 3 3 0 YbaB/EbfC DNA-binding family HEAT PF02985.22 AII57423.1 - 0.53 10.7 4.6 5.3 7.6 0.0 3.9 5 0 0 5 5 5 0 HEAT repeat N6_Mtase PF02384.16 AII57424.1 - 7.2e-06 25.5 0.0 0.062 12.6 0.0 2.4 2 0 0 2 2 2 2 N-6 DNA Methylase UPF0020 PF01170.18 AII57424.1 - 0.0015 18.3 0.0 0.34 10.6 0.0 2.3 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 AviRa PF11599.8 AII57424.1 - 0.0048 16.4 0.6 0.081 12.4 0.1 2.5 2 1 1 3 3 3 1 RRNA methyltransferase AviRa PglZ PF08665.12 AII57425.1 - 0.0047 17.0 0.0 4.2 7.4 0.0 2.4 2 0 0 2 2 2 2 PglZ domain Lon_2 PF13337.6 AII57426.1 - 6.6e-180 598.5 0.0 7.7e-180 598.3 0.0 1.0 1 0 0 1 1 1 1 Putative ATP-dependent Lon protease ChlI PF13541.6 AII57426.1 - 0.00024 20.9 0.0 0.00065 19.5 0.0 1.8 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Lon_C PF05362.13 AII57426.1 - 0.00035 20.2 0.0 0.00052 19.6 0.0 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain IstB_IS21 PF01695.17 AII57426.1 - 0.0033 17.2 0.0 0.0074 16.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein SMODS PF18144.1 AII57428.1 - 6e-44 150.1 0.4 9.4e-44 149.5 0.4 1.2 1 0 0 1 1 1 1 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain ThiF PF00899.21 AII57429.1 - 1.5e-21 76.8 0.0 2.1e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 ThiF family 2-Hacid_dh_C PF02826.19 AII57429.1 - 0.0043 16.4 0.0 0.013 14.9 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 AII57429.1 - 0.069 13.2 0.3 0.22 11.6 0.1 1.8 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 AII57429.1 - 0.23 10.5 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Prok-JAB PF14464.6 AII57430.1 - 5.9e-15 55.1 0.0 7e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain JAB PF01398.21 AII57430.1 - 6.3e-05 22.9 0.0 9.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MerR_1 PF13411.6 AII57431.1 - 5.7e-15 55.2 0.0 6.7e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 AII57431.1 - 3.3e-08 33.2 0.5 5.7e-08 32.4 0.1 1.7 2 0 0 2 2 2 1 MerR family regulatory protein MerR_2 PF13591.6 AII57431.1 - 8e-08 32.0 0.0 9.8e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 MerR HTH family regulatory protein HSP20 PF00011.21 AII57432.1 - 7.1e-24 83.9 0.5 9e-24 83.6 0.5 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 AII57432.1 - 1.2e-10 40.8 0.0 2.7e-10 39.6 0.0 1.6 1 1 1 2 2 2 1 HSP20-like domain found in ArsA CS PF04969.16 AII57432.1 - 0.0032 18.5 0.1 0.02 15.9 0.0 1.9 1 1 1 2 2 2 1 CS domain GvpH PF05455.11 AII57432.1 - 0.0067 16.5 0.1 0.01 15.9 0.1 1.3 1 0 0 1 1 1 1 GvpH RNase_PH_C PF03725.15 AII57432.1 - 0.015 15.3 0.1 0.028 14.5 0.1 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 FKBP26_C PF18046.1 AII57432.1 - 0.017 15.2 2.0 5.4 7.2 0.1 2.9 2 1 1 3 3 3 0 FKBP26_C-terminal SMI1_KNR4 PF09346.10 AII57433.1 - 0.0039 17.6 0.8 0.0085 16.5 0.8 1.9 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_5 PF14567.6 AII57433.1 - 0.011 15.5 1.0 0.045 13.5 0.2 2.2 2 1 0 2 2 2 0 SMI1-KNR4 cell-wall DDE_Tnp_IS1595 PF12762.7 AII57434.1 - 3.2e-47 160.4 0.3 4.7e-47 159.8 0.3 1.3 1 0 0 1 1 1 1 ISXO2-like transposase domain Zn_Tnp_IS1595 PF12760.7 AII57434.1 - 1.3e-10 41.1 1.2 2.6e-10 40.1 1.2 1.5 1 0 0 1 1 1 1 Transposase zinc-ribbon domain HTH_Tnp_ISL3 PF13542.6 AII57434.1 - 0.03 13.7 0.1 0.071 12.5 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 AII57434.1 - 0.042 13.7 0.2 0.096 12.5 0.2 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_11 PF08279.12 AII57434.1 - 0.044 13.7 0.0 0.09 12.7 0.0 1.4 1 0 0 1 1 1 0 HTH domain Ribosomal_L24e PF01246.20 AII57434.1 - 0.094 13.0 0.8 0.54 10.5 0.8 2.2 1 1 0 1 1 1 0 Ribosomal protein L24e CpXC PF14353.6 AII57434.1 - 0.098 12.7 1.1 0.89 9.6 0.0 2.3 1 1 1 2 2 2 0 CpXC protein Zn_ribbon_SprT PF17283.2 AII57434.1 - 0.26 11.2 5.1 0.59 10.1 5.1 1.5 1 0 0 1 1 1 0 SprT-like zinc ribbon domain zf-ribbon_3 PF13248.6 AII57434.1 - 0.45 10.0 5.6 3.2 7.3 0.2 2.9 3 0 0 3 3 3 0 zinc-ribbon domain zf_UBZ PF18439.1 AII57434.1 - 3.1 7.5 5.6 8.2 6.1 0.1 2.7 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Response_reg PF00072.24 AII57435.1 - 9e-24 83.8 0.1 1.4e-23 83.2 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AII57435.1 - 2.7e-15 56.2 0.2 6.1e-15 55.1 0.0 1.6 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Nucleolin_bd PF16725.5 AII57435.1 - 0.093 12.4 0.1 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Nucleolin binding domain B12-binding PF02310.19 AII57436.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 B12 binding domain Dehalogenase PF13486.6 AII57437.1 - 1.4e-17 64.0 0.0 1.8e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Reductive dehalogenase subunit Fer4_16 PF13484.6 AII57437.1 - 4.9e-10 40.2 8.6 4.9e-10 40.2 8.6 2.0 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 AII57437.1 - 1.3e-07 32.1 7.6 2.9e-07 30.9 7.6 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain TAT_signal PF10518.9 AII57437.1 - 0.00017 21.3 1.5 0.00032 20.4 1.5 1.5 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence Fer4_2 PF12797.7 AII57437.1 - 0.00031 20.7 7.4 0.18 11.9 0.6 2.8 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4 PF00037.27 AII57437.1 - 0.001 18.8 9.1 0.013 15.3 2.0 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 AII57437.1 - 0.0013 18.9 11.7 0.27 11.4 1.5 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 AII57437.1 - 0.0026 17.9 6.1 0.8 9.9 1.2 2.7 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AII57437.1 - 0.021 15.0 10.3 0.11 12.7 10.3 2.2 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 AII57437.1 - 0.038 14.1 14.5 0.11 12.6 3.3 2.7 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 AII57437.1 - 0.099 13.2 10.0 0.44 11.1 7.1 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain DUF202 PF02656.15 AII57438.1 - 0.011 16.1 3.0 0.011 16.1 3.0 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF202) KdpA PF03814.15 AII57438.1 - 0.015 13.5 0.4 0.016 13.5 0.4 1.1 1 0 0 1 1 1 0 Potassium-transporting ATPase A subunit TssN PF17555.2 AII57438.1 - 0.091 12.1 2.4 0.11 11.9 2.4 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN Curto_V3 PF07436.11 AII57438.1 - 0.12 12.7 0.2 0.18 12.2 0.2 1.3 1 0 0 1 1 1 0 Curtovirus V3 protein Tetraspanin PF00335.20 AII57438.1 - 1.5 8.5 5.1 2.1 8.0 5.1 1.2 1 0 0 1 1 1 0 Tetraspanin family FtsX PF02687.21 AII57438.1 - 8.3 7.0 12.5 18 5.9 6.6 2.7 1 1 1 2 2 2 0 FtsX-like permease family DUF4131 PF13567.6 AII57438.1 - 8.5 6.0 8.9 51 3.5 8.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DEAD PF00270.29 AII57439.1 - 3.2e-51 173.6 0.0 3e-50 170.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AII57439.1 - 6.1e-31 107.0 0.0 4.9e-29 100.9 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 AII57439.1 - 5.4e-08 33.0 0.0 1.1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 AII57439.1 - 0.00083 19.1 0.0 0.18 11.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain Flavi_DEAD PF07652.14 AII57439.1 - 0.0024 17.8 0.1 0.046 13.7 0.0 2.3 2 1 0 2 2 2 1 Flavivirus DEAD domain AAA_19 PF13245.6 AII57439.1 - 0.075 13.4 0.1 0.44 10.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain TerC PF03741.16 AII57440.1 - 2.7e-55 186.9 12.1 2.7e-55 186.9 12.1 2.2 3 0 0 3 3 3 1 Integral membrane protein TerC family DUF4225 PF13988.6 AII57440.1 - 0.081 12.5 0.6 0.33 10.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4225) S_4TM PF18159.1 AII57440.1 - 0.19 11.0 0.0 0.19 11.0 0.0 2.3 3 0 0 3 3 3 0 SMODS-associating 4TM effector domain YpmT PF17431.2 AII57440.1 - 3 8.0 8.7 6.8 6.8 6.3 2.9 2 1 0 2 2 2 0 Uncharacterized YmpT-like FdhE PF04216.12 AII57441.1 - 5.2e-24 85.6 0.0 7.2e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 Protein involved in formate dehydrogenase formation Prim_Zn_Ribbon PF08273.12 AII57441.1 - 0.0038 17.5 1.3 0.0038 17.5 1.3 2.0 2 0 0 2 2 2 1 Zinc-binding domain of primase-helicase PhnA_Zn_Ribbon PF08274.12 AII57441.1 - 0.019 14.9 0.9 0.9 9.5 0.1 2.5 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Zn_Tnp_IS1595 PF12760.7 AII57441.1 - 0.036 14.0 2.0 0.036 14.0 2.0 2.7 1 1 2 3 3 3 0 Transposase zinc-ribbon domain zinc_ribbon_15 PF17032.5 AII57441.1 - 0.21 12.3 6.6 0.38 11.5 6.6 1.4 1 0 0 1 1 1 0 zinc-ribbon family DZR PF12773.7 AII57441.1 - 0.57 10.3 8.8 25 5.0 8.8 2.5 1 1 0 1 1 1 0 Double zinc ribbon Prok-RING_4 PF14447.6 AII57441.1 - 0.94 9.4 6.8 2.5 8.0 0.1 2.9 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 DUF3268 PF11672.8 AII57441.1 - 1.1 9.7 5.6 1.3 9.4 1.2 2.2 2 0 0 2 2 2 0 zinc-finger-containing domain zf-C3HC4_3 PF13920.6 AII57441.1 - 1.9 8.4 9.5 1.3 8.9 4.7 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-ribbon_3 PF13248.6 AII57441.1 - 3.8 7.1 7.0 2.4 7.7 0.4 3.0 3 0 0 3 3 3 0 zinc-ribbon domain NrfD PF03916.14 AII57442.1 - 2.4e-20 73.4 28.6 3.5e-20 72.9 28.6 1.2 1 0 0 1 1 1 1 Polysulphide reductase, NrfD Molybdopterin PF00384.22 AII57443.1 - 9.7e-39 133.5 0.0 2.6e-38 132.1 0.0 1.7 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 AII57443.1 - 3.9e-15 55.8 0.0 1.5e-14 54.0 0.0 2.1 1 1 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 AII57443.1 - 1.2e-11 44.4 0.2 2.8e-11 43.2 0.2 1.7 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain TAT_signal PF10518.9 AII57443.1 - 4.2e-05 23.2 1.3 0.00015 21.4 1.3 2.1 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence Asp_protease_2 PF13650.6 AII57443.1 - 0.12 13.0 0.2 0.64 10.7 0.2 2.2 1 1 0 1 1 1 0 Aspartyl protease Cons_hypoth95 PF03602.15 AII57444.1 - 3.1e-42 144.3 0.0 3.4e-42 144.1 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 AII57444.1 - 4.1e-08 33.0 0.0 6.2e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 AII57444.1 - 0.00015 21.3 0.0 0.00024 20.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 AII57444.1 - 0.00042 21.0 0.0 0.00072 20.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6-adenineMlase PF10237.9 AII57444.1 - 0.0028 17.5 0.0 0.0035 17.2 0.0 1.2 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Methyltransf_16 PF10294.9 AII57444.1 - 0.021 14.5 0.0 0.026 14.3 0.0 1.1 1 0 0 1 1 1 0 Lysine methyltransferase UPF0020 PF01170.18 AII57444.1 - 0.026 14.2 0.1 0.11 12.1 0.1 1.9 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 RsmJ PF04378.13 AII57444.1 - 0.091 12.0 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA large subunit methyltransferase D, RlmJ Methyltransf_15 PF09445.10 AII57444.1 - 0.16 11.5 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase DUF43 PF01861.16 AII57444.1 - 0.17 11.1 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain CTP_transf_like PF01467.26 AII57445.1 - 1.7e-13 51.0 0.0 2e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like Citrate_ly_lig PF08218.11 AII57445.1 - 3.7e-05 23.5 0.0 5.8e-05 22.8 0.0 1.3 1 1 0 1 1 1 1 Citrate lyase ligase C-terminal domain Fer4 PF00037.27 AII57446.1 - 3.2e-07 29.9 3.9 3.2e-07 29.9 3.9 4.0 3 1 1 4 4 4 3 4Fe-4S binding domain Fer4_7 PF12838.7 AII57446.1 - 2.7e-06 27.9 11.1 2.7e-06 27.9 11.1 2.4 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AII57446.1 - 7.1e-06 26.1 9.8 7.1e-06 26.1 9.8 2.3 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AII57446.1 - 1.1e-05 25.4 11.7 1.1e-05 25.4 11.7 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 AII57446.1 - 0.0013 18.7 12.6 0.013 15.5 3.5 3.1 2 1 1 3 3 3 2 4Fe-4S binding domain Fer4_6 PF12837.7 AII57446.1 - 0.0036 17.3 3.6 0.0036 17.3 3.6 3.2 2 1 0 2 2 2 1 4Fe-4S binding domain GF_recep_IV PF14843.6 AII57446.1 - 0.011 15.5 15.6 0.028 14.2 15.6 1.7 1 1 0 1 1 1 0 Growth factor receptor domain IV Fer4_17 PF13534.6 AII57446.1 - 0.023 15.2 4.5 0.023 15.2 4.5 2.9 1 1 2 3 3 2 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 AII57446.1 - 0.031 14.4 21.1 0.04 14.1 19.6 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 AII57446.1 - 0.033 14.7 3.6 0.033 14.7 3.6 2.8 1 1 2 3 3 1 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 AII57446.1 - 0.038 14.5 3.2 0.038 14.5 3.2 3.7 2 1 1 3 3 3 0 4Fe-4S binding domain Fer4_3 PF12798.7 AII57446.1 - 0.059 14.3 15.2 0.18 12.8 2.3 3.4 2 1 1 3 3 3 0 4Fe-4S binding domain Fer4_16 PF13484.6 AII57446.1 - 0.85 10.6 23.4 1.8e+02 3.1 23.4 2.8 1 1 0 1 1 1 0 4Fe-4S double cluster binding domain Colicin_V PF02674.16 AII57447.1 - 3.5e-29 101.6 19.4 4.1e-29 101.4 19.4 1.0 1 0 0 1 1 1 1 Colicin V production protein DUF1129 PF06570.11 AII57447.1 - 0.0049 16.4 9.9 0.0049 16.4 9.9 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1129) P5CR_dimer PF14748.6 AII57448.1 - 4.3e-33 113.6 2.7 4.3e-33 113.6 2.7 2.0 3 0 0 3 3 3 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 AII57448.1 - 2.8e-21 75.9 2.2 3.7e-21 75.5 0.6 2.0 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 AII57448.1 - 5.7e-05 23.3 0.5 0.001 19.2 0.1 2.4 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 AII57448.1 - 0.00033 20.7 2.3 0.0019 18.2 2.3 2.0 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GFO_IDH_MocA PF01408.22 AII57448.1 - 0.024 15.5 0.0 0.085 13.7 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 AII57448.1 - 0.032 14.5 0.1 0.075 13.3 0.1 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Rossmann-like PF10727.9 AII57448.1 - 0.078 12.8 0.7 0.36 10.7 0.2 2.3 1 1 2 3 3 3 0 Rossmann-like domain Shikimate_DH PF01488.20 AII57448.1 - 0.11 12.6 0.2 0.2 11.7 0.2 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 AII57448.1 - 0.13 11.9 1.3 0.29 10.8 1.3 1.7 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PDH PF02153.17 AII57448.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase tRNA-synt_1 PF00133.22 AII57449.1 - 9.3e-70 235.5 0.3 1.3e-43 149.2 2.6 4.9 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 AII57449.1 - 6.5e-66 221.4 0.0 9.8e-66 220.8 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 AII57449.1 - 1.5e-34 119.4 0.5 4e-23 81.8 0.0 4.9 4 1 1 5 5 5 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 AII57449.1 - 6.2e-23 81.4 1.4 1.1e-22 80.6 1.4 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 AII57449.1 - 0.00051 19.5 0.0 0.0091 15.4 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 AII57449.1 - 0.0018 17.2 0.0 0.0058 15.6 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (K) DZR PF12773.7 AII57449.1 - 0.029 14.4 4.9 3.1 7.9 0.7 2.5 2 0 0 2 2 2 0 Double zinc ribbon DNA_ligase_ZBD PF03119.16 AII57449.1 - 0.048 13.7 7.0 0.17 11.9 0.1 2.7 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain TackOD1 PF18551.1 AII57449.1 - 0.13 11.9 0.4 0.9 9.2 0.0 2.2 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 IBR PF01485.21 AII57449.1 - 0.17 12.2 1.2 6.9 7.0 0.4 2.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Lar_restr_allev PF14354.6 AII57449.1 - 0.24 11.8 5.4 16 6.0 0.2 3.4 3 0 0 3 3 3 0 Restriction alleviation protein Lar HypA PF01155.19 AII57449.1 - 0.71 9.9 2.8 7.3 6.7 0.1 2.7 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ACC PF17848.1 AII57449.1 - 1.3 9.1 5.9 5.2 7.2 0.0 3.7 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain Zn-ribbon_8 PF09723.10 AII57449.1 - 9.8 6.4 9.3 3.6 7.8 0.1 3.4 3 1 0 3 3 3 0 Zinc ribbon domain HI0933_like PF03486.14 AII57450.1 - 3.6e-121 404.7 0.0 9.1e-121 403.4 0.0 1.5 1 1 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 AII57450.1 - 4.5e-12 45.8 9.8 1.5e-07 30.8 2.3 3.3 2 1 0 3 3 3 3 FAD binding domain Pyr_redox_2 PF07992.14 AII57450.1 - 4.2e-11 42.6 0.5 6.9e-11 41.9 0.3 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AII57450.1 - 6.2e-09 35.4 6.3 0.0039 16.3 0.6 3.1 3 0 0 3 3 3 3 Glucose inhibited division protein A FAD_oxidored PF12831.7 AII57450.1 - 3.9e-08 33.1 1.4 5.4e-08 32.6 1.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 AII57450.1 - 1.1e-06 28.5 5.8 0.0039 16.8 0.5 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AII57450.1 - 0.001 18.4 5.6 0.51 9.6 0.1 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AII57450.1 - 0.0016 18.7 0.4 0.0046 17.2 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 AII57450.1 - 0.0052 17.3 2.2 0.022 15.3 0.6 2.5 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 AII57450.1 - 0.0073 15.6 0.8 0.017 14.4 0.4 1.8 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 AII57450.1 - 0.018 14.3 1.0 0.037 13.3 1.0 1.7 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 AII57450.1 - 0.021 14.1 0.7 0.048 12.9 0.2 1.7 1 1 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 AII57450.1 - 0.024 14.6 1.1 0.23 11.4 1.1 2.4 1 1 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 AII57450.1 - 0.043 13.1 0.4 0.075 12.3 0.4 1.4 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 AII57450.1 - 1.7 7.6 3.7 0.77 8.7 0.7 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein GrpB PF04229.14 AII57451.1 - 4e-51 173.4 0.0 4.6e-51 173.2 0.0 1.0 1 0 0 1 1 1 1 GrpB protein MHB PF16525.5 AII57451.1 - 0.065 13.5 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Haemophore, haem-binding DUF2769 PF10967.8 AII57452.1 - 3.3e-07 30.9 16.7 8.2e-06 26.4 16.6 2.6 1 1 2 3 3 3 2 Protein of unknown function (DUF2769) Whib PF02467.16 AII57452.1 - 0.081 13.5 0.8 0.081 13.5 0.8 2.2 2 0 0 2 2 2 0 Transcription factor WhiB Glutaredoxin PF00462.24 AII57453.1 - 7e-10 39.0 0.0 1.1e-09 38.3 0.0 1.4 2 0 0 2 2 2 1 Glutaredoxin GST_N_3 PF13417.6 AII57453.1 - 6.2e-05 23.3 0.0 8.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 AII57453.1 - 0.00062 20.0 0.0 0.00078 19.7 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 AII57453.1 - 0.001 19.4 0.0 0.0013 19.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain FeThRed_B PF02943.15 AII57454.1 - 2.1e-23 82.3 0.1 3.7e-23 81.6 0.1 1.3 1 0 0 1 1 1 1 Ferredoxin thioredoxin reductase catalytic beta chain NRDD PF13597.6 AII57454.1 - 0.28 9.9 0.4 0.4 9.4 0.4 1.1 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase DUF1616 PF07760.11 AII57455.1 - 2e-52 178.4 0.0 2.5e-52 178.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1616) CbtB PF09489.10 AII57455.1 - 0.031 14.4 1.6 2.3 8.4 0.1 2.8 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) Dpy19 PF10034.9 AII57455.1 - 0.18 9.9 0.0 0.26 9.5 0.0 1.2 1 0 0 1 1 1 0 Q-cell neuroblast polarisation Borrelia_P13 PF05628.12 AII57455.1 - 0.38 10.7 4.5 15 5.5 2.9 2.3 2 0 0 2 2 2 0 Borrelia membrane protein P13 YfhO PF09586.10 AII57455.1 - 0.39 8.9 5.0 0.54 8.4 5.0 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF2070 PF09843.9 AII57455.1 - 0.59 8.4 2.8 0.72 8.1 2.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4131 PF13567.6 AII57455.1 - 5 6.8 9.4 0.75 9.4 0.5 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Glyco_trans_1_4 PF13692.6 AII57456.1 - 3.8e-12 46.8 0.0 7.8e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AII57456.1 - 2.4e-09 36.9 0.0 1.7e-08 34.2 0.0 2.2 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AII57456.1 - 2.3e-05 24.4 0.0 0.00019 21.5 0.0 2.4 3 0 0 3 3 3 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AII57456.1 - 0.0024 18.2 0.0 0.0062 16.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_2 PF00535.26 AII57457.1 - 1.7e-10 41.0 0.0 5.2e-10 39.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Hydrolase_like PF13242.6 AII57457.1 - 1.4e-09 37.9 0.0 2.8e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 AII57457.1 - 1.7e-08 34.7 0.0 1.5e-06 28.4 0.0 2.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase PNK3P PF08645.11 AII57457.1 - 7.3e-07 29.0 0.0 1.1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase Hydrolase_6 PF13344.6 AII57457.1 - 5e-05 23.3 0.0 8.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AII57457.1 - 0.00016 22.1 0.0 0.0087 16.4 0.0 2.4 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase PIG-L PF02585.17 AII57458.1 - 4.6e-28 98.5 0.0 6.5e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Aldo_ket_red PF00248.21 AII57459.1 - 1.7e-60 204.7 0.0 2.2e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family MlaA PF04333.13 AII57459.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 MlaA lipoprotein DUF134 PF02001.16 AII57460.1 - 8.2e-23 80.8 0.0 9.5e-23 80.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF134 Sigma70_r4_2 PF08281.12 AII57460.1 - 1.6e-07 30.9 0.2 2.2e-07 30.4 0.2 1.2 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AII57460.1 - 0.00023 21.1 0.1 0.00028 20.8 0.1 1.1 1 0 0 1 1 1 1 ECF sigma factor HTH_23 PF13384.6 AII57460.1 - 0.00034 20.3 0.0 0.00068 19.4 0.0 1.5 1 1 0 1 1 1 1 Homeodomain-like domain HTH_37 PF13744.6 AII57460.1 - 0.0013 18.7 0.9 0.006 16.5 0.9 2.0 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 AII57460.1 - 0.0094 16.0 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix Sigma70_r4 PF04545.16 AII57460.1 - 0.019 14.5 0.2 0.03 13.8 0.2 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_10 PF04967.12 AII57460.1 - 0.074 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain SoPB_HTH PF18090.1 AII57460.1 - 0.1 12.7 0.1 0.21 11.7 0.1 1.5 2 0 0 2 2 2 0 Centromere-binding protein HTH domain Phage_NinH PF06322.11 AII57460.1 - 0.17 11.8 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Phage NinH protein HEAT_2 PF13646.6 AII57461.1 - 8.2e-12 45.4 1.9 7.4e-09 35.9 0.2 2.6 1 1 2 3 3 3 2 HEAT repeats HEAT PF02985.22 AII57461.1 - 0.00019 21.4 0.1 1 9.8 0.0 3.5 3 0 0 3 3 3 2 HEAT repeat HEAT_PBS PF03130.16 AII57461.1 - 0.018 15.7 6.1 7.3 7.6 0.1 3.9 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Cnd1 PF12717.7 AII57461.1 - 0.052 13.6 0.0 0.17 11.9 0.0 1.9 1 1 2 3 3 3 0 non-SMC mitotic condensation complex subunit 1 LAM_C PF12544.8 AII57462.1 - 1.9e-40 138.0 0.0 3.9e-40 137.0 0.0 1.5 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Radical_SAM PF04055.21 AII57462.1 - 9e-13 48.9 0.0 3.2e-12 47.1 0.0 2.0 1 1 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 AII57462.1 - 7.7e-08 32.6 0.1 2e-06 28.0 0.0 3.1 4 0 0 4 4 4 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 AII57462.1 - 1.9e-06 28.0 0.1 1e-05 25.6 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Fer4_14 PF13394.6 AII57462.1 - 2.1e-05 24.6 0.0 5.8e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 4Fe-4S single cluster domain Acetyltransf_10 PF13673.7 AII57462.1 - 0.00019 21.3 0.0 0.00048 20.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Fer4_12 PF13353.6 AII57462.1 - 0.0017 18.7 0.0 0.0033 17.7 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Acetyltransf_7 PF13508.7 AII57462.1 - 0.16 12.4 0.0 0.43 11.0 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Serpin PF00079.20 AII57463.1 - 7.8e-110 367.7 0.2 9e-110 367.5 0.2 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF4223 PF13978.6 AII57463.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4223) HlyIII PF03006.20 AII57464.1 - 2.1e-37 129.0 13.4 2.6e-37 128.7 13.4 1.0 1 0 0 1 1 1 1 Haemolysin-III related ABC_tran PF00005.27 AII57465.1 - 4.1e-44 150.4 0.7 1.1e-21 77.8 0.0 3.6 3 1 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 AII57465.1 - 6.2e-27 93.5 15.0 1.3e-24 86.0 6.4 3.2 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 AII57465.1 - 1.1e-19 71.4 9.0 0.00013 21.9 0.5 4.4 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AII57465.1 - 8.7e-13 48.2 0.3 0.00023 20.7 0.0 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain ABC_tran_CTD PF16326.5 AII57465.1 - 6.6e-11 42.3 2.5 6.6e-11 42.3 2.5 4.2 4 1 1 5 5 4 1 ABC transporter C-terminal domain AAA_29 PF13555.6 AII57465.1 - 3.7e-07 29.8 0.3 0.043 13.6 0.0 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA PF00004.29 AII57465.1 - 4.9e-06 27.0 0.0 0.2 12.1 0.0 3.1 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 AII57465.1 - 5e-06 27.2 22.1 0.0085 16.6 0.1 4.6 5 0 0 5 5 4 2 AAA domain AAA_5 PF07728.14 AII57465.1 - 9.2e-06 25.7 0.0 0.06 13.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 AII57465.1 - 1.3e-05 25.0 0.0 0.042 13.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 AII57465.1 - 2.3e-05 24.9 0.8 0.042 14.2 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 AII57465.1 - 3.3e-05 24.2 0.6 0.31 11.3 0.0 3.2 3 1 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 AII57465.1 - 7e-05 22.8 1.0 0.37 10.7 0.0 3.2 3 0 0 3 3 3 2 RsgA GTPase cobW PF02492.19 AII57465.1 - 7.3e-05 22.4 0.8 1.6 8.3 0.1 3.6 4 0 0 4 4 3 2 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 AII57465.1 - 7.5e-05 23.0 0.0 0.24 11.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain SRP54 PF00448.22 AII57465.1 - 0.00014 21.6 0.2 0.71 9.5 0.0 2.7 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_24 PF13479.6 AII57465.1 - 0.00016 21.5 0.0 0.18 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 AII57465.1 - 0.00016 21.7 0.3 0.36 10.7 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.6 AII57465.1 - 0.00018 22.0 0.1 0.91 10.1 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.6 AII57465.1 - 0.00021 21.5 0.0 1.2 9.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 AII57465.1 - 0.00029 20.8 0.3 0.93 9.5 0.1 2.8 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 AII57465.1 - 0.00036 20.0 0.0 0.22 10.8 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 AII57465.1 - 0.00039 20.2 0.1 0.91 9.3 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 AII57465.1 - 0.0016 18.0 0.2 0.2 11.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 AII57465.1 - 0.0028 17.6 0.1 0.92 9.4 0.0 2.9 2 0 0 2 2 2 1 NTPase Dynamin_N PF00350.23 AII57465.1 - 0.0036 17.4 1.4 2 8.4 0.0 3.9 4 0 0 4 4 4 1 Dynamin family Cytidylate_kin PF02224.18 AII57465.1 - 0.0038 17.0 0.0 1.2 8.8 0.0 2.6 2 0 0 2 2 2 1 Cytidylate kinase DUF4094 PF13334.6 AII57465.1 - 0.0044 17.4 1.8 1.4 9.4 0.0 3.0 3 0 0 3 3 2 1 Domain of unknown function (DUF4094) AAA_15 PF13175.6 AII57465.1 - 0.0046 16.7 12.2 0.32 10.7 0.0 4.5 5 0 0 5 5 5 1 AAA ATPase domain MMR_HSR1 PF01926.23 AII57465.1 - 0.0047 17.0 0.1 5 7.2 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 AII57465.1 - 0.0063 16.9 0.0 5.2 7.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 AII57465.1 - 0.0064 16.0 0.0 1.9 8.0 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Roc PF08477.13 AII57465.1 - 0.0083 16.3 0.3 4.7 7.4 0.0 2.8 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 AII57465.1 - 0.012 15.4 0.0 7 6.4 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 AII57465.1 - 0.013 15.4 0.5 2.4 8.0 0.0 3.0 3 1 1 4 4 2 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 AII57465.1 - 0.014 14.4 0.1 0.97 8.4 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein G-alpha PF00503.20 AII57465.1 - 0.022 14.0 0.0 0.76 8.9 0.0 2.4 2 1 0 2 2 2 0 G-protein alpha subunit AAA_14 PF13173.6 AII57465.1 - 0.022 14.8 0.0 9.7 6.2 0.0 3.0 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 AII57465.1 - 0.022 14.6 0.1 7.5 6.5 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.6 AII57465.1 - 0.031 14.7 0.2 17 5.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 AII57465.1 - 0.032 14.0 0.1 7.3 6.3 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein dNK PF01712.19 AII57465.1 - 0.04 13.8 0.0 2.5 7.9 0.0 2.5 2 0 0 2 2 2 0 Deoxynucleoside kinase NB-ARC PF00931.22 AII57465.1 - 0.046 12.9 0.3 3.9 6.6 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.12 AII57465.1 - 0.048 12.9 0.1 10 5.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Thymidylate_kin PF02223.17 AII57465.1 - 0.075 12.7 4.7 1.2 8.8 0.0 3.3 3 0 0 3 3 3 0 Thymidylate kinase Rad17 PF03215.15 AII57465.1 - 0.094 12.6 0.0 4.3 7.2 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain ATP_bind_1 PF03029.17 AII57465.1 - 0.12 12.2 0.1 17 5.1 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 AII57465.1 - 0.12 11.8 0.0 14 5.1 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B GIT_CC PF16559.5 AII57465.1 - 0.15 11.9 8.1 2.5 8.0 0.2 4.3 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor AAA_13 PF13166.6 AII57465.1 - 0.59 8.7 13.0 4.1 5.9 0.0 4.0 4 0 0 4 4 4 0 AAA domain Lzipper-MIP1 PF14389.6 AII57465.1 - 0.61 10.4 8.1 0.81 10.0 0.6 3.8 4 0 0 4 4 2 0 Leucine-zipper of ternary complex factor MIP1 AAA_27 PF13514.6 AII57465.1 - 4.5 6.8 7.1 8 6.0 0.0 3.4 4 0 0 4 4 3 0 AAA domain Exonuc_VII_L PF02601.15 AII57465.1 - 8.8 5.8 10.5 2.1 7.8 0.6 2.6 3 0 0 3 3 3 0 Exonuclease VII, large subunit LolA_like PF17131.4 AII57466.1 - 0.0036 17.1 0.8 0.32 10.7 0.8 2.4 1 1 0 1 1 1 1 Outer membrane lipoprotein-sorting protein DUF4412 PF14371.6 AII57466.1 - 0.053 13.3 0.2 0.053 13.3 0.2 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4412) DUF3558 PF12079.8 AII57466.1 - 0.18 11.8 4.6 0.12 12.4 2.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3558) HI0933_like PF03486.14 AII57467.1 - 2.6e-94 316.2 0.0 3.4e-94 315.9 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 AII57467.1 - 0.0023 17.1 0.9 0.0038 16.4 0.2 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 AII57467.1 - 0.0041 16.3 0.0 1.1 8.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain zinc_ribbon_2 PF13240.6 AII57468.1 - 2e-08 33.7 2.8 2e-08 33.7 2.8 1.7 2 0 0 2 2 2 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 AII57468.1 - 2.3e-06 26.8 2.1 4.3e-06 25.9 2.1 1.5 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 AII57468.1 - 6.3e-05 22.9 1.9 6.3e-05 22.9 1.9 1.7 2 0 0 2 2 2 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 AII57468.1 - 0.00036 21.2 0.7 0.00062 20.5 0.7 1.4 1 0 0 1 1 1 1 zinc-ribbon family Nudix_N_2 PF14803.6 AII57468.1 - 0.00062 19.6 2.5 0.43 10.5 0.1 2.2 2 0 0 2 2 2 2 Nudix N-terminal zinc-ribbons_6 PF07191.12 AII57468.1 - 0.00085 19.3 0.6 0.0012 18.8 0.6 1.2 1 0 0 1 1 1 1 zinc-ribbons Prok-RING_1 PF14446.6 AII57468.1 - 0.0038 17.1 1.1 0.0074 16.2 1.1 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 Saf_2TM PF18303.1 AII57468.1 - 0.0086 15.7 0.1 0.011 15.4 0.1 1.1 1 0 0 1 1 1 1 SAVED-fused 2TM effector domain zf-NADH-PPase PF09297.11 AII57468.1 - 0.014 15.1 4.8 0.61 9.8 0.3 2.9 2 1 1 3 3 3 0 NADH pyrophosphatase zinc ribbon domain zf-C3HC4_3 PF13920.6 AII57468.1 - 0.02 14.8 0.3 0.034 14.0 0.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UPF0547 PF10571.9 AII57468.1 - 0.029 14.5 2.6 0.029 14.5 2.6 1.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 YhfH PF14149.6 AII57468.1 - 0.038 14.0 1.5 8.3 6.5 0.1 2.4 2 0 0 2 2 2 0 YhfH-like protein Proton_antipo_M PF00361.20 AII57468.1 - 0.039 13.2 0.4 0.048 12.8 0.4 1.1 1 0 0 1 1 1 0 Proton-conducting membrane transporter DUF1610 PF07754.11 AII57468.1 - 0.062 13.3 4.8 0.25 11.4 4.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1610) zf_UBZ PF18439.1 AII57468.1 - 0.068 12.8 2.2 0.76 9.4 0.2 2.2 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger HypA PF01155.19 AII57468.1 - 0.13 12.3 0.8 0.2 11.7 0.8 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF35_N PF12172.8 AII57468.1 - 0.13 12.1 2.4 0.32 10.9 2.4 1.6 1 1 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DHHC PF01529.20 AII57468.1 - 0.2 11.7 5.4 5.4 7.1 0.3 2.3 2 1 0 2 2 2 0 DHHC palmitoyltransferase Sgf11 PF08209.11 AII57468.1 - 0.26 10.9 0.2 0.26 10.9 0.2 2.2 2 1 1 3 3 3 0 Sgf11 (transcriptional regulation protein) Zn-ribbon_8 PF09723.10 AII57468.1 - 0.51 10.5 3.8 2.5 8.3 3.2 2.1 1 1 1 2 2 2 0 Zinc ribbon domain NOB1_Zn_bind PF08772.11 AII57468.1 - 0.82 9.9 7.0 24 5.2 0.8 2.2 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like TF_Zn_Ribbon PF08271.12 AII57468.1 - 1.1 8.8 6.2 7.3 6.2 0.4 2.3 1 1 1 2 2 2 0 TFIIB zinc-binding zf-HYPF PF07503.12 AII57468.1 - 3.9 7.3 6.3 5.9 6.8 0.3 2.7 2 1 1 3 3 3 0 HypF finger TM2 PF05154.16 AII57469.1 - 8.5e-17 61.2 7.4 1.2e-16 60.8 7.4 1.2 1 0 0 1 1 1 1 TM2 domain zinc_ribbon_2 PF13240.6 AII57469.1 - 4.5e-08 32.5 3.3 6.1e-08 32.1 3.3 1.2 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 AII57469.1 - 3e-07 29.6 2.8 4e-07 29.2 2.8 1.2 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 AII57469.1 - 0.00012 22.0 1.3 0.00016 21.6 1.3 1.1 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 AII57469.1 - 0.00088 20.0 3.2 0.0012 19.5 3.2 1.2 1 0 0 1 1 1 1 zinc-ribbon family Nudix_N_2 PF14803.6 AII57469.1 - 0.0084 16.0 4.7 1 9.3 0.2 2.2 1 1 1 2 2 2 2 Nudix N-terminal YhfH PF14149.6 AII57469.1 - 0.016 15.1 1.8 3 7.9 0.1 2.2 2 0 0 2 2 2 0 YhfH-like protein RNA_POL_M_15KD PF02150.16 AII57469.1 - 0.025 14.4 1.6 0.07 13.0 0.0 2.1 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zinc-ribbons_6 PF07191.12 AII57469.1 - 0.036 14.0 0.7 0.047 13.7 0.7 1.1 1 0 0 1 1 1 0 zinc-ribbons zf_UBZ PF18439.1 AII57469.1 - 0.039 13.6 1.4 6.2 6.5 0.1 2.2 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C3HC4_3 PF13920.6 AII57469.1 - 0.041 13.7 0.6 0.054 13.4 0.6 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 AII57469.1 - 0.061 12.9 0.4 0.079 12.6 0.4 1.2 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-NADH-PPase PF09297.11 AII57469.1 - 0.079 12.6 1.4 5.5 6.8 0.2 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain HypA PF01155.19 AII57469.1 - 0.083 12.9 1.4 0.14 12.2 1.4 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA OrfB_Zn_ribbon PF07282.11 AII57469.1 - 0.086 12.8 1.5 0.12 12.3 1.5 1.2 1 0 0 1 1 1 0 Putative transposase DNA-binding domain UPF0547 PF10571.9 AII57469.1 - 0.1 12.7 2.0 0.16 12.1 2.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 Sgf11 PF08209.11 AII57469.1 - 0.39 10.3 2.2 1.6 8.4 0.3 2.2 1 1 1 2 2 2 0 Sgf11 (transcriptional regulation protein) NRDD PF13597.6 AII57469.1 - 0.43 9.3 0.9 0.54 9.0 0.9 1.2 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase NOB1_Zn_bind PF08772.11 AII57469.1 - 0.49 10.6 4.7 1.5 9.0 4.7 1.7 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zf-LITAF-like PF10601.9 AII57469.1 - 0.52 10.6 4.8 4.4 7.6 0.1 2.5 2 1 1 3 3 3 0 LITAF-like zinc ribbon domain Zn-ribbon_8 PF09723.10 AII57469.1 - 0.6 10.3 3.6 1.2 9.3 3.6 1.5 1 1 0 1 1 1 0 Zinc ribbon domain RecR PF02132.15 AII57469.1 - 0.61 9.7 3.4 1.3 8.7 0.1 2.1 1 1 1 2 2 1 0 RecR protein Zn_Tnp_IS1595 PF12760.7 AII57469.1 - 1.2 9.1 3.6 2.5 8.2 0.2 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain DUF11 PF01345.18 AII57470.1 - 1.2e-05 25.5 3.5 0.0045 17.3 2.0 2.8 2 0 0 2 2 2 2 Domain of unknown function DUF11 EF-hand_10 PF14788.6 AII57470.1 - 0.011 15.6 0.0 0.31 10.9 0.0 2.6 3 0 0 3 3 3 0 EF hand CBM-like PF14683.6 AII57470.1 - 0.035 14.0 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain III TRAP_beta PF05753.14 AII57470.1 - 0.037 13.4 1.2 7.2 6.0 0.1 3.1 3 0 0 3 3 3 0 Translocon-associated protein beta (TRAPB) Fer4_5 PF12801.7 AII57471.1 - 4.1e-14 52.2 8.7 8.7e-10 38.4 1.3 3.6 4 0 0 4 4 4 2 4Fe-4S binding domain FMN_bind PF04205.14 AII57471.1 - 1.8e-10 41.2 0.0 3.7e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 FMN-binding domain Fer4 PF00037.27 AII57471.1 - 0.016 15.0 0.7 1.5 8.8 0.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain SKG6 PF08693.10 AII57472.1 - 0.088 12.2 1.2 0.088 12.2 1.2 2.1 3 0 0 3 3 3 0 Transmembrane alpha-helix domain Response_reg PF00072.24 AII57473.1 - 2.6e-23 82.3 0.5 5.2e-23 81.4 0.3 1.6 2 0 0 2 2 2 1 Response regulator receiver domain Trans_reg_C PF00486.28 AII57473.1 - 7.3e-11 42.0 0.1 1.3e-10 41.2 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal DUF2573 PF10835.8 AII57473.1 - 0.061 13.7 0.2 0.17 12.2 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2573) HATPase_c PF02518.26 AII57474.1 - 1.9e-21 76.7 0.0 3.9e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AII57474.1 - 1e-09 38.3 0.9 1.8e-09 37.5 0.1 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 AII57474.1 - 4.2e-08 33.0 0.0 1.1e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 AII57474.1 - 2.5e-07 30.9 0.1 1.1e-06 28.9 0.0 2.1 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 AII57474.1 - 3.8e-05 23.7 0.0 0.00011 22.1 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 AII57474.1 - 0.00052 20.2 0.0 0.0014 18.9 0.0 1.8 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 AII57474.1 - 0.00065 19.5 0.0 0.0022 17.8 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AII57474.1 - 0.0057 16.5 0.1 0.013 15.4 0.1 1.6 1 0 0 1 1 1 1 GHKL domain PAS_4 PF08448.10 AII57474.1 - 0.029 14.6 0.0 0.05 13.9 0.0 1.4 1 0 0 1 1 1 0 PAS fold DOCK-C2 PF14429.6 AII57474.1 - 0.051 13.4 0.3 0.12 12.2 0.0 1.8 2 1 0 2 2 2 0 C2 domain in Dock180 and Zizimin proteins Ig_4 PF16680.5 AII57474.1 - 0.11 12.7 0.1 13 6.1 0.0 2.6 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain CxxCxxCC PF03692.15 AII57475.1 - 3e-06 27.8 5.7 1.3e-05 25.8 5.7 2.0 1 1 0 1 1 1 1 Putative zinc- or iron-chelating domain Response_reg PF00072.24 AII57476.1 - 1.1e-24 86.8 0.1 1.9e-24 86.0 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AII57476.1 - 2e-17 63.1 0.0 4.8e-17 61.8 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal HATPase_c PF02518.26 AII57477.1 - 1.8e-23 83.2 0.3 3.7e-23 82.2 0.1 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 AII57477.1 - 8.7e-10 38.8 0.1 2.3e-09 37.4 0.1 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AII57477.1 - 1.4e-08 34.7 0.0 3.3e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 AII57477.1 - 5e-07 29.9 0.0 5.6e-06 26.5 0.0 2.7 3 0 0 3 3 3 1 PAS fold HisKA PF00512.25 AII57477.1 - 5.1e-06 26.4 0.0 9.9e-05 22.3 0.0 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 AII57477.1 - 7e-06 25.9 0.0 1.5e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 AII57477.1 - 3.5e-05 23.7 0.0 8.7e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 AII57477.1 - 0.0042 17.3 0.0 0.0063 16.8 0.0 1.3 1 0 0 1 1 1 1 PAS fold DUF2310 PF10071.9 AII57477.1 - 0.055 12.7 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) Dehalogenase PF13486.6 AII57478.1 - 2.1e-93 312.9 0.0 2.9e-93 312.4 0.0 1.2 1 0 0 1 1 1 1 Reductive dehalogenase subunit Fer4_16 PF13484.6 AII57478.1 - 2.1e-12 47.8 7.3 3.6e-12 47.0 7.3 1.4 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 AII57478.1 - 0.00029 21.4 6.6 0.00053 20.5 6.6 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AII57478.1 - 0.001 19.2 5.3 0.01 16.0 1.3 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 AII57478.1 - 0.0019 18.6 2.3 0.78 10.2 0.9 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 AII57478.1 - 0.0039 16.9 1.3 0.0039 16.9 1.3 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_17 PF13534.6 AII57478.1 - 0.004 17.7 1.7 0.29 11.7 0.4 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 AII57478.1 - 0.097 12.8 10.1 0.13 12.4 3.4 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_10 PF13237.6 AII57478.1 - 0.16 12.1 9.7 0.72 10.0 9.8 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 AII57478.1 - 0.27 11.4 4.9 0.14 12.3 0.6 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain TAT_signal PF10518.9 AII57478.1 - 0.42 10.5 5.1 1.5 8.7 5.1 2.0 1 1 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence AA_permease_2 PF13520.6 AII57479.1 - 0.0045 15.9 5.1 0.006 15.5 5.1 1.2 1 1 0 1 1 1 1 Amino acid permease DUF2892 PF11127.8 AII57479.1 - 0.047 13.7 3.2 0.047 13.7 3.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) DUF751 PF05421.11 AII57479.1 - 0.047 14.4 2.5 0.047 14.4 2.5 1.7 1 1 0 2 2 2 0 Protein of unknown function (DUF751) ABC2_membrane_5 PF13346.6 AII57479.1 - 0.063 12.8 5.5 0.068 12.7 5.5 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2919 PF11143.8 AII57479.1 - 0.16 12.3 8.7 0.19 12.0 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2919) Tmemb_14 PF03647.13 AII57479.1 - 0.19 12.5 4.0 0.36 11.6 4.0 1.5 1 1 0 1 1 1 0 Transmembrane proteins 14C EamA PF00892.20 AII57479.1 - 0.21 11.8 11.3 0.24 11.6 11.3 1.1 1 0 0 1 1 1 0 EamA-like transporter family Wzy_C PF04932.15 AII57479.1 - 0.76 9.4 6.5 0.35 10.5 4.3 1.5 1 1 0 1 1 1 0 O-Antigen ligase 5TM-5TMR_LYT PF07694.12 AII57479.1 - 0.81 9.2 7.8 0.91 9.0 7.8 1.0 1 0 0 1 1 1 0 5TMR of 5TMR-LYT DUF1418 PF07214.12 AII57479.1 - 1.2 9.0 7.4 0.1 12.4 2.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1418) DUF3810 PF12725.7 AII57479.1 - 1.5 8.1 4.4 1.5 8.1 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Tetraspanin PF00335.20 AII57479.1 - 2.1 8.0 5.8 2.4 7.8 5.8 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF4131 PF13567.6 AII57479.1 - 5.2 6.7 9.7 12 5.5 9.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Patatin PF01734.22 AII57480.1 - 2.3e-27 96.5 0.0 4e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Abhydrolase_1 PF00561.20 AII57480.1 - 0.075 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Acetyltransf_3 PF13302.7 AII57481.1 - 2.7e-26 92.9 0.0 3.7e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AII57481.1 - 8.5e-06 26.0 0.1 1.2e-05 25.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 AII57481.1 - 2.7e-05 24.4 0.0 3.1e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 AII57481.1 - 0.007 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF87 PF01935.17 AII57482.1 - 2.3e-27 96.6 0.3 6.2e-27 95.2 0.1 1.8 2 0 0 2 2 2 1 Helicase HerA, central domain HAS-barrel PF09378.10 AII57482.1 - 1.6e-07 31.4 0.1 5.4e-07 29.7 0.1 2.0 1 0 0 1 1 1 1 HAS barrel domain AAA_22 PF13401.6 AII57482.1 - 0.0022 18.2 0.6 1.3 9.3 0.1 2.9 2 1 1 3 3 3 1 AAA domain ATPase PF06745.13 AII57482.1 - 0.003 17.0 0.5 0.85 8.9 0.1 2.3 2 0 0 2 2 2 2 KaiC AAA_16 PF13191.6 AII57482.1 - 0.0098 16.3 0.1 0.49 10.8 0.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain DUF853 PF05872.12 AII57482.1 - 0.047 12.3 0.0 0.43 9.1 0.0 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) PhoH PF02562.16 AII57482.1 - 0.057 12.9 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.29 AII57482.1 - 0.058 13.8 0.5 10 6.6 0.1 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 AII57482.1 - 0.11 13.0 0.5 0.39 11.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 AII57482.1 - 0.11 12.5 0.0 0.26 11.4 0.0 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NurA PF09376.10 AII57484.1 - 4.4e-22 78.9 0.0 5.8e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 NurA domain LysE PF01810.18 AII57485.1 - 6.4e-29 100.8 18.0 7.6e-29 100.5 18.0 1.1 1 0 0 1 1 1 1 LysE type translocator MarC PF01914.17 AII57485.1 - 0.013 14.9 8.8 0.041 13.3 8.3 1.9 1 1 0 1 1 1 0 MarC family integral membrane protein DPM3 PF08285.11 AII57485.1 - 3 8.1 12.7 2.2 8.5 1.1 2.8 2 1 1 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Syndecan PF01034.20 AII57485.1 - 6 6.9 6.4 8.6 6.4 0.0 3.3 3 0 0 3 3 3 0 Syndecan domain Hist_deacetyl PF00850.19 AII57486.1 - 4.1e-79 266.2 0.5 8.4e-79 265.2 0.5 1.4 1 1 0 1 1 1 1 Histone deacetylase domain Cation_efflux PF01545.21 AII57487.1 - 1.1e-48 165.7 14.9 1.4e-48 165.3 14.9 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 AII57487.1 - 6.8e-25 87.0 0.4 1.1e-24 86.3 0.4 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter PAP2_C PF14360.6 AII57487.1 - 4.9 7.8 6.2 3.2 8.3 0.3 3.0 2 1 1 3 3 3 0 PAP2 superfamily C-terminal SecD_SecF PF02355.16 AII57488.1 - 1.1e-50 171.6 9.1 1.1e-50 171.6 9.1 1.5 2 0 0 2 2 2 1 Protein export membrane protein Sec_GG PF07549.14 AII57488.1 - 1.6e-07 30.6 0.2 3.6e-07 29.5 0.2 1.7 1 0 0 1 1 1 1 SecD/SecF GG Motif ACR_tran PF00873.19 AII57488.1 - 5e-05 21.2 9.4 6.6e-05 20.8 9.4 1.2 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family Glycophorin_A PF01102.18 AII57488.1 - 0.31 11.3 3.2 3.1 8.1 0.0 3.0 2 1 0 2 2 2 0 Glycophorin A Ndc1_Nup PF09531.10 AII57488.1 - 0.36 9.5 2.0 0.45 9.2 2.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MMPL PF03176.15 AII57488.1 - 2.3 7.0 13.6 0.024 13.6 6.0 1.6 2 0 0 2 2 2 0 MMPL family DUF3671 PF12420.8 AII57488.1 - 9.3 6.4 8.9 24 5.1 2.9 2.8 2 1 1 3 3 3 0 Protein of unknown function SecD_SecF PF02355.16 AII57489.1 - 1.9e-13 50.2 9.7 5.2e-13 48.8 9.9 1.5 2 0 0 2 2 2 1 Protein export membrane protein Sec_GG PF07549.14 AII57489.1 - 0.0015 17.9 0.4 0.0038 16.7 0.4 1.7 1 0 0 1 1 1 1 SecD/SecF GG Motif MMPL PF03176.15 AII57489.1 - 0.0047 15.9 21.4 0.0047 15.9 21.4 1.4 2 0 0 2 2 2 1 MMPL family PolyA_pol_RNAbd PF12627.7 AII57490.1 - 2.7e-13 49.4 0.7 1.3e-12 47.3 0.0 2.5 3 0 0 3 3 3 1 Probable RNA and SrmB- binding site of polymerase A PolyA_pol PF01743.20 AII57490.1 - 6.8e-12 45.9 0.0 0.00012 22.5 0.0 2.5 1 1 1 2 2 2 2 Poly A polymerase head domain tRNA_NucTran2_2 PF13735.6 AII57490.1 - 6.2e-11 42.5 0.0 1.5e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative HD PF01966.22 AII57490.1 - 1.3e-07 31.9 0.0 4.1e-07 30.2 0.0 1.9 1 0 0 1 1 1 1 HD domain NTP_transf_2 PF01909.23 AII57490.1 - 0.0012 19.1 0.0 0.0025 18.1 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain RAMA PF18755.1 AII57490.1 - 0.018 15.4 0.0 0.053 13.9 0.0 1.8 1 0 0 1 1 1 0 Restriction Enzyme Adenine Methylase Associated HTH_3 PF01381.22 AII57491.1 - 3.3e-12 46.3 0.2 8.4e-12 45.0 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix HTH_31 PF13560.6 AII57491.1 - 3.1e-11 43.5 0.0 5.9e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AII57491.1 - 5e-10 39.2 0.0 1.9e-09 37.4 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_25 PF13413.6 AII57491.1 - 3.4e-06 26.8 0.1 7.6e-06 25.7 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_6 PF01418.17 AII57491.1 - 0.15 12.1 0.2 21 5.2 0.2 2.4 2 1 0 2 2 2 0 Helix-turn-helix domain, rpiR family PriA_3primeBD PF17764.1 AII57492.1 - 2.1e-20 72.4 0.0 5.3e-20 71.1 0.0 1.7 1 0 0 1 1 1 1 3′ DNA-binding domain (3′BD) PriA_C PF18074.1 AII57492.1 - 1.7e-16 60.8 0.0 7.9e-16 58.7 0.0 2.2 2 0 0 2 2 2 1 Primosomal protein N C-terminal domain ResIII PF04851.15 AII57492.1 - 1.6e-13 51.0 0.0 2.7e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 AII57492.1 - 4.9e-12 46.0 0.0 1.2e-11 44.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AII57492.1 - 8.1e-11 42.2 0.0 5.3e-08 33.2 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PriA_CRR PF18319.1 AII57492.1 - 1.2e-08 34.8 5.1 1.2e-08 34.8 5.1 2.3 3 0 0 3 3 3 1 PriA DNA helicase Cys-rich region (CRR) domain zinc-ribbons_6 PF07191.12 AII57492.1 - 0.0018 18.2 4.6 0.0043 17.0 4.6 1.6 1 0 0 1 1 1 1 zinc-ribbons SBDS PF01172.18 AII57492.1 - 0.0065 16.5 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein AAA_16 PF13191.6 AII57492.1 - 0.078 13.4 0.0 0.22 11.9 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain TrmB PF01978.19 AII57492.1 - 0.16 11.8 0.0 13 5.7 0.0 2.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB DUF2318 PF10080.9 AII57492.1 - 0.2 11.8 3.6 0.43 10.7 3.6 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) TF_Zn_Ribbon PF08271.12 AII57492.1 - 0.21 11.1 7.8 9.1 5.9 4.8 3.2 2 1 1 3 3 3 0 TFIIB zinc-binding HypA PF01155.19 AII57492.1 - 0.8 9.7 7.9 0.32 11.0 3.7 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA PhnA_Zn_Ribbon PF08274.12 AII57492.1 - 1.9 8.5 8.9 0.74 9.8 2.3 2.5 2 0 0 2 2 2 0 PhnA Zinc-Ribbon DZR PF12773.7 AII57492.1 - 2.9 8.0 12.0 17 5.5 12.0 2.2 1 1 0 1 1 1 0 Double zinc ribbon Ribosomal_L19 PF01245.20 AII57493.1 - 1.2e-42 144.4 1.3 1.5e-42 144.0 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L19 tRNA_m1G_MT PF01746.21 AII57494.1 - 2.1e-70 236.4 0.0 2.4e-70 236.2 0.0 1.0 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase MraZ PF02381.18 AII57495.1 - 1e-25 89.5 0.0 7e-16 58.0 0.0 2.1 2 0 0 2 2 2 2 MraZ protein, putative antitoxin-like Methyltransf_5 PF01795.19 AII57496.1 - 4.1e-113 378.0 0.0 5e-113 377.7 0.0 1.1 1 0 0 1 1 1 1 MraW methylase family Methyltransf_31 PF13847.6 AII57496.1 - 6.3e-05 22.8 0.0 0.028 14.2 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 AII57496.1 - 0.027 15.2 0.0 0.56 11.0 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 AII57496.1 - 0.044 14.5 0.0 0.13 12.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain DUF3719 PF12516.8 AII57496.1 - 0.044 13.5 0.0 0.097 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3719) rRNA_methylase PF06962.12 AII57496.1 - 0.049 13.6 0.0 5.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Putative rRNA methylase FtsA PF14450.6 AII57497.1 - 1.4e-33 115.4 0.3 1.1e-21 77.2 0.0 2.2 2 0 0 2 2 2 2 Cell division protein FtsA SHS2_FTSA PF02491.20 AII57497.1 - 1.1e-27 96.2 0.3 2e-27 95.4 0.3 1.5 1 0 0 1 1 1 1 SHS2 domain inserted in FTSA MreB_Mbl PF06723.13 AII57497.1 - 2.6e-08 33.1 3.7 3.1e-07 29.5 1.0 2.9 2 1 0 2 2 2 1 MreB/Mbl protein PilM_2 PF11104.8 AII57497.1 - 7.9e-08 31.7 0.0 3.8e-05 22.9 0.0 2.9 3 0 0 3 3 3 2 Type IV pilus assembly protein PilM; EutA PF06277.11 AII57497.1 - 6.7e-05 21.9 0.0 0.00015 20.8 0.0 1.6 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutA DDR PF08841.10 AII57497.1 - 0.00023 20.2 0.1 0.00043 19.4 0.1 1.4 1 0 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 AII57497.1 - 0.0077 15.5 0.2 0.015 14.5 0.1 1.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Tubulin PF00091.25 AII57498.1 - 1.6e-40 139.5 0.4 2.3e-40 138.9 0.4 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 AII57498.1 - 1.2e-30 105.7 0.7 3.1e-30 104.3 0.1 2.0 2 0 0 2 2 2 1 FtsZ family, C-terminal domain Tubulin_2 PF13809.6 AII57498.1 - 0.25 10.5 4.9 3.8 6.6 2.0 2.2 1 1 0 2 2 2 0 Tubulin like ATP-cone PF03477.16 AII57499.1 - 3.5e-18 65.9 0.0 6.3e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 ATP cone domain DUF2387 PF09526.10 AII57499.1 - 0.03 14.5 0.7 0.049 13.8 0.7 1.4 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) Cys_rich_CPXG PF14255.6 AII57499.1 - 0.49 10.3 2.8 1.1 9.2 2.8 1.6 1 1 0 1 1 1 0 Cysteine-rich CPXCG zf-C2H2_4 PF13894.6 AII57499.1 - 2.1 9.4 4.3 3.7 8.6 0.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Ribonuc_red_lgC PF02867.15 AII57500.1 - 2e-156 521.6 0.0 1.4e-154 515.5 0.0 2.4 1 1 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 AII57500.1 - 5.2e-28 96.9 0.1 1e-27 95.9 0.1 1.5 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain TSCPD PF12637.7 AII57500.1 - 1.6e-10 41.0 1.1 5.3e-10 39.4 1.1 1.9 1 0 0 1 1 1 1 TSCPD domain PhnA_Zn_Ribbon PF08274.12 AII57500.1 - 0.00027 20.8 1.0 0.0006 19.7 1.0 1.6 1 0 0 1 1 1 1 PhnA Zinc-Ribbon TF_Zn_Ribbon PF08271.12 AII57500.1 - 0.18 11.3 5.9 0.5 9.9 5.9 1.8 1 0 0 1 1 1 0 TFIIB zinc-binding Auto_anti-p27 PF06677.12 AII57500.1 - 0.37 11.0 3.6 0.79 9.9 3.6 1.6 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) OrfB_Zn_ribbon PF07282.11 AII57500.1 - 2 8.4 5.8 4 7.4 4.8 2.1 2 0 0 2 2 2 0 Putative transposase DNA-binding domain NYN PF01936.18 AII57502.1 - 1.3e-34 119.8 0.0 1.6e-34 119.5 0.0 1.0 1 0 0 1 1 1 1 NYN domain ADH_zinc_N PF00107.26 AII57502.1 - 0.014 15.4 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pept_S41_N PF18294.1 AII57502.1 - 0.023 14.7 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase S41 N-terminal domain Radical_SAM PF04055.21 AII57503.1 - 3.4e-19 69.9 0.0 5.6e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily YqeY PF09424.10 AII57504.1 - 1.5e-47 161.3 8.5 1.6e-47 161.2 8.5 1.0 1 0 0 1 1 1 1 Yqey-like protein GatB_Yqey PF02637.18 AII57504.1 - 0.00014 21.7 9.0 0.00046 20.1 9.0 1.8 1 1 0 1 1 1 1 GatB domain TRAF_BIRC3_bd PF16673.5 AII57504.1 - 0.01 15.6 0.8 0.02 14.7 0.8 1.5 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain CCDC84 PF14968.6 AII57504.1 - 0.12 12.0 0.5 0.12 12.0 0.5 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 EMC3_TMCO1 PF01956.16 AII57504.1 - 1.9 8.2 4.7 2.9 7.6 4.7 1.3 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Ribosomal_S21 PF01165.20 AII57505.1 - 3.4e-16 58.7 7.9 3.4e-16 58.7 7.9 1.5 1 1 1 2 2 2 2 Ribosomal protein S21 TIG PF01833.24 AII57506.1 - 2e-15 56.6 60.1 2.4e-05 24.3 5.4 5.3 3 2 2 5 5 5 5 IPT/TIG domain MG2 PF01835.19 AII57506.1 - 0.00019 21.8 6.4 0.14 12.7 0.1 4.8 4 1 0 5 5 5 1 MG2 domain LIFR_N PF18207.1 AII57506.1 - 0.00056 20.2 0.5 14 6.1 0.0 3.8 4 0 0 4 4 4 2 Leukemia inhibitory factor receptor N-terminal domain DUF4469 PF14734.6 AII57506.1 - 0.002 18.3 5.2 0.5 10.6 0.6 4.2 2 1 2 4 4 4 1 Domain of unknown function (DUF4469) with IG-like fold Big_7 PF17957.1 AII57506.1 - 0.039 14.7 1.9 0.039 14.7 1.9 7.1 6 2 0 6 6 6 0 Bacterial Ig domain Wzt_C PF14524.6 AII57506.1 - 0.045 13.8 2.7 1.1 9.3 0.0 3.3 3 1 0 3 3 3 0 Wzt C-terminal domain DUF2012 PF09430.10 AII57506.1 - 0.047 13.8 0.6 7.3 6.7 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF2012) Mor PF08765.11 AII57507.1 - 5.1e-05 23.2 0.1 6.5e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 Mor transcription activator family HTH_23 PF13384.6 AII57507.1 - 0.0086 15.8 1.3 0.027 14.3 1.3 1.8 1 1 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.15 AII57507.1 - 0.042 13.9 0.1 0.059 13.4 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_36 PF13730.6 AII57507.1 - 0.084 12.8 0.0 0.68 9.9 0.0 2.1 1 1 0 1 1 1 0 Helix-turn-helix domain Terminase_6C PF17289.2 AII57509.1 - 5.2e-05 23.4 0.0 9.6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Terminase RNaseH-like domain zf-RING_7 PF02591.15 AII57511.1 - 4.7e-07 29.9 1.4 1.6e-06 28.2 1.4 2.0 1 0 0 1 1 1 1 C4-type zinc ribbon domain FliD_N PF02465.18 AII57511.1 - 0.0034 18.0 9.6 0.1 13.3 0.2 2.7 2 1 0 2 2 2 2 Flagellar hook-associated protein 2 N-terminus PI_PP_I PF18363.1 AII57511.1 - 0.09 13.0 6.3 0.047 13.9 1.8 2.3 1 1 0 2 2 2 0 Phosphoinositide phosphatase insertion domain Prominin PF05478.11 AII57511.1 - 0.13 10.2 7.2 0.16 9.9 7.2 1.2 1 0 0 1 1 1 0 Prominin Spc7 PF08317.11 AII57511.1 - 0.24 10.2 24.8 0.39 9.5 23.9 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF3450 PF11932.8 AII57511.1 - 0.35 10.1 18.2 0.36 10.1 10.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF4407 PF14362.6 AII57511.1 - 0.48 9.7 13.5 1.8 7.8 13.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF948 PF06103.11 AII57511.1 - 1.1 9.6 7.1 0.71 10.2 0.3 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FapA PF03961.13 AII57511.1 - 1.5 7.4 15.2 0.81 8.2 2.3 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A Syntaxin-6_N PF09177.11 AII57511.1 - 1.5 9.4 13.7 0.74 10.4 4.3 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Mod_r PF07200.13 AII57511.1 - 2.2 8.3 25.8 0.19 11.8 10.6 2.8 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein T3SSipB PF16535.5 AII57511.1 - 2.8 8.4 16.9 1.4 9.4 13.0 1.9 1 1 1 2 2 2 0 Type III cell invasion protein SipB Fib_alpha PF08702.10 AII57511.1 - 3.1 8.0 12.5 3.9 7.7 7.5 2.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Nup88 PF10168.9 AII57511.1 - 3.4 5.4 16.3 4.2 5.1 16.3 1.1 1 0 0 1 1 1 0 Nuclear pore component DUF2203 PF09969.9 AII57511.1 - 3.6 8.3 11.2 3.6 8.3 6.0 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) ACCA PF03255.14 AII57511.1 - 5.8 6.8 9.4 7 6.5 0.9 2.4 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit RVT_3 PF13456.6 AII57512.1 - 8.2e-29 99.9 0.0 9.2e-29 99.8 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase-like RNase_H PF00075.24 AII57512.1 - 3.3e-12 46.8 0.0 6.6e-12 45.8 0.0 1.5 1 1 0 1 1 1 1 RNase H DUF4328 PF14219.6 AII57513.1 - 1.7e-19 70.0 0.2 2.2e-19 69.6 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4328) DUF2767 PF10965.8 AII57514.1 - 0.034 14.1 0.2 0.061 13.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2767) Peptidase_S41 PF03572.18 AII57515.1 - 1.3e-49 167.9 0.4 2.1e-49 167.3 0.4 1.3 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 AII57515.1 - 2.6e-14 52.8 0.1 5.1e-14 51.9 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 AII57515.1 - 2e-09 37.6 0.0 5.8e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 AII57515.1 - 8.5e-08 32.5 0.0 2e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 AII57515.1 - 0.0035 17.3 0.1 0.018 15.0 0.0 2.2 2 0 0 2 2 2 1 Tricorn protease PDZ domain tRNA-synt_2d PF01409.20 AII57516.1 - 1e-104 349.4 0.0 1.2e-104 349.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) Phe_tRNA-synt_N PF02912.18 AII57516.1 - 2.7e-20 72.0 3.3 4.6e-20 71.3 3.3 1.4 1 0 0 1 1 1 1 Aminoacyl tRNA synthetase class II, N-terminal domain B3_4 PF03483.17 AII57517.1 - 8.8e-66 220.9 0.0 1.4e-65 220.2 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain tRNA_synthFbeta PF17759.1 AII57517.1 - 9.3e-56 188.6 0.0 1.5e-55 187.9 0.0 1.4 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain FDX-ACB PF03147.14 AII57517.1 - 5.3e-27 94.1 0.3 1.1e-26 93.1 0.3 1.5 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA_bind PF01588.20 AII57517.1 - 9.4e-22 76.9 0.1 2.1e-21 75.8 0.1 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain B5 PF03484.15 AII57517.1 - 8.7e-13 48.4 0.2 4e-12 46.3 0.1 2.3 2 0 0 2 2 2 1 tRNA synthetase B5 domain PhetRS_B1 PF18262.1 AII57517.1 - 0.12 12.6 0.1 0.69 10.2 0.0 2.3 2 0 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain Pyrophosphatase PF00719.19 AII57518.1 - 2.4e-52 176.9 0.0 3.1e-52 176.6 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase tRNA-synt_2b PF00587.25 AII57519.1 - 7.8e-50 169.3 0.0 1.1e-49 168.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.15 AII57519.1 - 5.9e-24 84.5 0.0 1.1e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain HGTP_anticodon PF03129.20 AII57519.1 - 1.1e-17 63.9 0.1 3.6e-17 62.3 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain zinc_ribbon_9 PF14369.6 AII57519.1 - 0.015 15.5 0.3 6 7.2 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon tRNA-synt_His PF13393.6 AII57519.1 - 0.095 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Histidyl-tRNA synthetase zf-H2C2_2 PF13465.6 AII57519.1 - 0.11 13.0 1.6 12 6.6 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 AII57519.1 - 0.28 12.1 0.5 1.7 9.7 0.0 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger GcpE PF04551.14 AII57520.1 - 1.5e-128 428.8 0.0 1.7e-128 428.6 0.0 1.0 1 0 0 1 1 1 1 GcpE protein MR_MLE_C PF13378.6 AII57520.1 - 0.0029 17.2 0.0 0.0042 16.7 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like Peptidase_M50 PF02163.22 AII57521.1 - 1.5e-57 194.8 1.5 1.7e-57 194.6 1.5 1.0 1 0 0 1 1 1 1 Peptidase family M50 PDZ_6 PF17820.1 AII57521.1 - 3.2e-13 49.3 0.1 6e-13 48.4 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 AII57521.1 - 1.5e-10 41.3 0.0 2.9e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 AII57521.1 - 1.3e-07 31.9 0.1 3.1e-07 30.6 0.1 1.6 2 0 0 2 2 2 1 PDZ domain GRASP55_65 PF04495.14 AII57521.1 - 0.0099 16.2 0.0 0.017 15.5 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain Tricorn_PDZ PF14685.6 AII57521.1 - 0.015 15.2 0.1 0.025 14.5 0.1 1.4 1 0 0 1 1 1 0 Tricorn protease PDZ domain DXPR_C PF13288.6 AII57522.1 - 4.8e-42 142.9 0.0 7.8e-42 142.2 0.0 1.3 1 0 0 1 1 1 1 DXP reductoisomerase C-terminal domain DXP_redisom_C PF08436.12 AII57522.1 - 3.1e-38 129.8 0.0 1.1e-37 128.1 0.0 1.9 2 0 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain DXP_reductoisom PF02670.16 AII57522.1 - 7.6e-34 117.2 0.2 8.6e-33 113.8 0.2 2.2 1 1 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase GFO_IDH_MocA PF01408.22 AII57522.1 - 0.00069 20.4 0.0 0.0011 19.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 AII57522.1 - 0.0031 18.2 0.0 0.0089 16.7 0.0 1.8 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 AII57522.1 - 0.01 16.3 0.0 0.021 15.3 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain CTP_transf_1 PF01148.20 AII57523.1 - 4.6e-61 206.9 16.0 5.2e-61 206.7 16.0 1.0 1 0 0 1 1 1 1 Cytidylyltransferase family Caveolin PF01146.17 AII57523.1 - 7.8 6.5 8.1 23 4.9 0.3 2.4 2 0 0 2 2 2 0 Caveolin Prenyltransf PF01255.19 AII57524.1 - 9.8e-75 250.9 0.0 1.1e-74 250.7 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase RRF PF01765.19 AII57525.1 - 1e-58 197.9 0.3 1.3e-58 197.5 0.3 1.1 1 0 0 1 1 1 1 Ribosome recycling factor UPF0147 PF03685.13 AII57525.1 - 0.06 13.4 1.8 0.11 12.5 1.8 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) AA_kinase PF00696.28 AII57526.1 - 4.9e-24 85.2 1.2 5.7e-24 85.0 1.2 1.0 1 0 0 1 1 1 1 Amino acid kinase family EF_TS PF00889.19 AII57527.1 - 2.8e-22 79.4 3.7 4.4e-14 52.6 4.2 3.7 1 1 1 2 2 2 2 Elongation factor TS Ribosomal_S2 PF00318.20 AII57528.1 - 3.6e-94 314.0 0.0 4.1e-94 313.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S2 FliG_N PF14842.6 AII57528.1 - 0.13 12.8 0.8 0.56 10.8 0.0 2.3 3 0 0 3 3 3 0 FliG N-terminal domain GATase_5 PF13507.6 AII57529.1 - 4.1e-80 268.6 0.0 4.6e-80 268.4 0.0 1.0 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 AII57529.1 - 0.00021 21.1 0.0 0.00038 20.3 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 AII57529.1 - 0.00022 20.9 0.0 0.00033 20.3 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Pox_T4_N PF04491.12 AII57529.1 - 0.13 12.1 0.2 2.4 8.1 0.0 2.4 2 0 0 2 2 2 0 Poxvirus T4 protein, N terminus AIRS_C PF02769.22 AII57530.1 - 3.8e-53 179.8 0.8 8.7e-29 100.7 0.1 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.24 AII57530.1 - 9.9e-22 77.4 0.2 1e-14 54.9 0.0 2.6 2 0 0 2 2 2 2 AIR synthase related protein, N-terminal domain PurS PF02700.14 AII57530.1 - 6.3e-19 67.9 0.1 2.2e-08 34.1 0.0 2.6 2 0 0 2 2 2 2 Phosphoribosylformylglycinamidine (FGAM) synthase FGAR-AT_linker PF18072.1 AII57530.1 - 4.3e-16 59.2 2.1 8.2e-16 58.3 1.0 2.2 2 0 0 2 2 2 1 Formylglycinamide ribonucleotide amidotransferase linker domain SOR_SNZ PF01680.17 AII57531.1 - 9.3e-112 371.8 3.9 9.3e-112 371.8 3.9 1.5 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.14 AII57531.1 - 2.4e-10 40.2 8.2 8.3e-09 35.1 1.1 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 AII57531.1 - 0.00014 21.0 0.3 0.066 12.3 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.14 AII57531.1 - 0.00026 20.2 2.3 0.019 14.2 0.1 3.0 2 1 1 3 3 3 1 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.15 AII57531.1 - 0.0011 18.4 7.5 0.0066 15.9 0.7 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase IGPS PF00218.21 AII57531.1 - 0.006 15.8 0.1 0.11 11.7 0.0 2.3 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase DUF561 PF04481.12 AII57531.1 - 0.0062 15.7 0.9 0.29 10.3 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF561) His_biosynth PF00977.21 AII57531.1 - 0.008 15.7 0.4 0.2 11.1 0.0 2.4 2 1 0 2 2 2 1 Histidine biosynthesis protein Ribosomal_S5_C PF03719.15 AII57531.1 - 0.059 12.8 1.2 0.11 12.0 0.1 2.0 3 0 0 3 3 3 0 Ribosomal protein S5, C-terminal domain TetR_C_27 PF17935.1 AII57531.1 - 0.081 13.0 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain FMN_dh PF01070.18 AII57531.1 - 0.13 11.3 3.3 0.22 10.5 0.1 2.6 2 2 0 3 3 3 0 FMN-dependent dehydrogenase Rieske PF00355.26 AII57532.1 - 9.4e-09 35.1 0.0 1.2e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain IMPDH PF00478.25 AII57534.1 - 2.1e-54 184.8 7.9 4.4e-51 173.9 4.7 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 AII57534.1 - 5e-11 42.2 1.9 5e-11 42.2 1.9 2.9 3 1 0 3 3 3 1 FMN-dependent dehydrogenase NMO PF03060.15 AII57534.1 - 7e-10 38.8 5.5 4.7e-09 36.1 5.5 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 AII57534.1 - 3.3e-05 23.3 1.6 0.0013 18.0 0.0 2.5 2 1 0 2 2 2 1 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 AII57534.1 - 0.00094 18.4 0.3 0.00094 18.4 0.3 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase DHO_dh PF01180.21 AII57534.1 - 0.0022 17.2 1.0 0.0036 16.6 0.1 1.7 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase Trp_syntA PF00290.20 AII57534.1 - 0.0038 16.1 0.7 0.056 12.3 0.3 2.2 2 0 0 2 2 2 1 Tryptophan synthase alpha chain His_biosynth PF00977.21 AII57534.1 - 0.016 14.6 0.1 0.26 10.7 0.0 2.2 1 1 1 2 2 2 0 Histidine biosynthesis protein TP_methylase PF00590.20 AII57535.1 - 3.9e-28 98.8 0.2 5.3e-28 98.4 0.2 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases zf-RING_7 PF02591.15 AII57536.1 - 0.029 14.5 0.8 0.2 11.9 0.8 2.1 1 1 0 1 1 1 0 C4-type zinc ribbon domain zf-C2HCIx2C PF10782.9 AII57536.1 - 0.13 12.2 0.2 0.13 12.2 0.2 1.9 2 0 0 2 2 2 0 Zinc-finger tRNA-synt_1g PF09334.11 AII57537.1 - 6.5e-155 515.7 0.0 7.9e-155 515.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 AII57537.1 - 4.6e-21 74.7 0.4 1.2e-10 40.4 0.0 4.2 2 2 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 AII57537.1 - 1.7e-11 44.0 0.2 0.00054 19.4 0.0 3.4 4 0 0 4 4 4 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 AII57537.1 - 0.00023 21.2 0.0 0.00046 20.2 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA DZR PF12773.7 AII57537.1 - 0.0034 17.4 11.3 0.052 13.6 6.9 2.3 1 1 1 2 2 2 2 Double zinc ribbon zinc-ribbons_6 PF07191.12 AII57537.1 - 0.007 16.3 6.7 0.02 14.9 6.7 1.7 1 1 0 1 1 1 1 zinc-ribbons tRNA-synt_1f PF01921.18 AII57537.1 - 0.047 12.6 0.4 0.15 11.0 0.0 2.0 2 1 0 2 2 2 0 tRNA synthetases class I (K) HypA PF01155.19 AII57537.1 - 2 8.5 8.1 2.5 8.1 0.6 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_C2H2_10 PF18414.1 AII57537.1 - 4.7 6.8 5.1 4.4 6.9 0.5 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger zf-ribbon_3 PF13248.6 AII57537.1 - 5.5 6.5 15.2 10 5.7 0.1 3.8 3 1 0 3 3 3 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 AII57537.1 - 5.6 7.0 10.5 7.2 6.6 1.3 3.9 2 1 1 3 3 3 0 Putative transposase DNA-binding domain C1_1 PF00130.22 AII57537.1 - 5.9 6.9 8.7 0.79 9.7 0.7 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf_C2H2_13 PF18508.1 AII57537.1 - 7.5 6.2 7.0 4.9 6.8 0.2 2.4 1 1 1 2 2 2 0 Zinc finger domain polyprenyl_synt PF00348.17 AII57538.1 - 1.9e-61 207.4 0.0 2.4e-61 207.0 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Peptidase_M41 PF01434.18 AII57539.1 - 6.1e-67 225.2 1.9 9.4e-67 224.6 1.9 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 AII57539.1 - 1.6e-46 158.0 0.0 5.4e-46 156.3 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AII57539.1 - 3.4e-15 55.6 0.3 7.8e-15 54.4 0.3 1.7 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 AII57539.1 - 1.8e-06 28.2 1.8 1e-05 25.8 0.2 2.4 2 0 0 2 2 2 1 FtsH Extracellular AAA_5 PF07728.14 AII57539.1 - 7.9e-06 25.9 0.0 3.8e-05 23.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 AII57539.1 - 1.2e-05 24.7 1.5 1.4e-05 24.5 0.1 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_22 PF13401.6 AII57539.1 - 7.4e-05 23.0 0.3 0.038 14.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.12 AII57539.1 - 0.00012 21.9 0.0 0.00042 20.1 0.0 2.0 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 AII57539.1 - 0.00038 20.9 1.5 0.0045 17.4 1.5 2.6 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 AII57539.1 - 0.0012 18.6 0.0 0.0036 17.0 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.6 AII57539.1 - 0.0014 19.1 0.4 0.012 16.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 AII57539.1 - 0.0016 18.6 0.0 0.01 16.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 AII57539.1 - 0.0058 16.0 0.2 0.013 14.9 0.2 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 AII57539.1 - 0.0072 16.6 0.2 0.019 15.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 AII57539.1 - 0.013 15.7 0.0 0.053 13.7 0.0 2.1 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 AII57539.1 - 0.014 15.4 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 AII57539.1 - 0.014 15.9 0.2 0.042 14.4 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 AII57539.1 - 0.021 14.5 0.1 0.13 12.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 AII57539.1 - 0.12 12.9 0.1 0.46 11.0 0.1 2.0 1 0 0 1 1 1 0 ABC transporter Parvo_NS1 PF01057.17 AII57539.1 - 0.14 11.2 0.1 0.35 9.9 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 PduV-EutP PF10662.9 AII57539.1 - 0.18 11.5 1.2 1.1 9.0 0.0 2.5 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 AII57539.1 - 0.19 11.2 0.2 0.77 9.2 0.2 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 AII57539.1 - 1 9.7 3.5 1.9 8.8 0.8 2.8 2 1 1 3 3 3 0 AAA domain AP_endonuc_2 PF01261.24 AII57540.1 - 1.6e-16 60.4 0.0 1.9e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel RsfS PF02410.15 AII57541.1 - 1.9e-25 89.2 0.0 2.1e-25 89.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation NDK PF00334.19 AII57542.1 - 2.2e-52 176.6 0.0 2.5e-52 176.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase GatB_N PF02934.15 AII57542.1 - 0.13 11.6 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 GatB/GatE catalytic domain HAD_2 PF13419.6 AII57543.1 - 6.9e-37 127.2 0.0 1.3e-36 126.3 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Peptidase_M22 PF00814.25 AII57543.1 - 2.4e-18 66.8 0.2 4.8e-18 65.8 0.0 1.5 2 0 0 2 2 2 1 Glycoprotease family Hydrolase PF00702.26 AII57543.1 - 5.1e-17 62.9 0.1 5e-16 59.6 0.1 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AII57543.1 - 3.2e-08 33.5 0.0 5.6e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 AII57543.1 - 8e-07 29.6 0.0 1.3e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AII57543.1 - 0.0063 16.6 0.0 4.9 7.3 0.0 2.7 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 AII57543.1 - 0.015 15.1 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Acid Phosphatase TsaE PF02367.17 AII57544.1 - 5.1e-33 113.7 0.0 6.3e-33 113.4 0.0 1.1 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 AII57544.1 - 0.019 14.2 0.0 0.053 12.8 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin PhoH PF02562.16 AII57544.1 - 0.027 13.9 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_7 PF12775.7 AII57544.1 - 0.034 13.6 0.0 0.048 13.2 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 AII57544.1 - 0.065 13.0 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 AII57544.1 - 0.068 13.1 0.2 0.12 12.3 0.2 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 AII57544.1 - 0.072 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 AII57544.1 - 0.073 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 ABC_tran PF00005.27 AII57544.1 - 0.079 13.5 0.0 0.089 13.3 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 AII57544.1 - 0.13 12.8 0.1 0.18 12.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AII57544.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 AII57544.1 - 0.17 11.6 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AIRS PF00586.24 AII57545.1 - 1.5e-16 60.8 0.3 2.6e-16 60.0 0.3 1.4 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain AIRS_C PF02769.22 AII57545.1 - 5.6e-07 29.8 0.0 9.5e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain Ubie_methyltran PF01209.18 AII57546.1 - 7e-44 149.9 0.3 8.4e-44 149.6 0.3 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 AII57546.1 - 5.1e-17 62.1 0.0 6.4e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AII57546.1 - 9e-17 61.6 0.0 2.5e-16 60.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 AII57546.1 - 1.8e-14 54.1 0.0 4.7e-14 52.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 AII57546.1 - 5.2e-11 43.2 0.0 8e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AII57546.1 - 7.7e-11 42.1 0.0 1e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AII57546.1 - 5.9e-07 29.2 0.0 8.9e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 AII57546.1 - 0.00029 20.2 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain CMAS PF02353.20 AII57546.1 - 0.02 14.2 0.0 0.041 13.2 0.0 1.6 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 AII57546.1 - 0.021 14.8 0.0 0.031 14.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Tox-REase-5 PF15648.6 AII57546.1 - 0.025 15.1 0.1 0.045 14.3 0.1 1.5 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 5 Methyltransf_15 PF09445.10 AII57546.1 - 0.049 13.2 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_8 PF05148.15 AII57546.1 - 0.12 12.2 0.0 0.95 9.3 0.0 2.0 2 0 0 2 2 2 0 Hypothetical methyltransferase Ubie_methyltran PF01209.18 AII57547.1 - 3.4e-38 131.3 0.1 4.1e-38 131.0 0.1 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 AII57547.1 - 8.5e-19 67.8 0.0 1.2e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AII57547.1 - 3.7e-16 59.6 0.0 7e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AII57547.1 - 3.7e-15 56.3 0.0 7.1e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AII57547.1 - 9.6e-13 48.7 0.0 1.5e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AII57547.1 - 6.4e-12 45.6 0.0 9.1e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AII57547.1 - 5.2e-08 32.6 0.0 8.6e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 AII57547.1 - 1.2e-06 28.5 0.0 1.9e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 AII57547.1 - 4.3e-05 22.9 0.0 6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_PK PF05891.12 AII57547.1 - 0.00047 19.7 0.0 0.00088 18.8 0.0 1.4 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase CMAS PF02353.20 AII57547.1 - 0.04 13.2 0.0 0.078 12.3 0.0 1.6 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 AII57547.1 - 0.16 12.0 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DHQ_synthase PF01761.20 AII57548.1 - 3.2e-76 256.0 0.0 4.9e-76 255.3 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 AII57548.1 - 2e-14 53.9 0.1 4.9e-12 46.1 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 AII57548.1 - 1.7e-10 40.3 0.0 4.6e-09 35.5 0.0 2.1 1 1 1 2 2 2 2 Iron-containing alcohol dehydrogenase UbiA PF01040.18 AII57549.1 - 3.4e-27 95.4 19.7 4.7e-27 94.9 19.7 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family SLATT_1 PF18181.1 AII57549.1 - 6.1 6.8 6.0 34 4.4 0.2 3.0 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 Methyltransf_11 PF08241.12 AII57550.1 - 2e-16 60.4 0.1 7e-16 58.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 AII57550.1 - 4.6e-14 52.9 0.0 1.4e-13 51.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 AII57550.1 - 2e-13 50.2 0.0 9.6e-13 48.0 0.0 1.7 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 AII57550.1 - 3.2e-11 43.3 0.0 4e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AII57550.1 - 1.7e-08 34.4 0.0 2.1e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AII57550.1 - 1.1e-06 29.3 0.0 2.2e-06 28.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 AII57550.1 - 0.0048 16.2 0.0 0.0072 15.6 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 AII57550.1 - 0.033 13.7 0.0 0.052 13.1 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 AII57550.1 - 0.1 12.6 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Metallophos_2 PF12850.7 AII57551.1 - 2.1e-24 86.6 0.0 2.8e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 AII57551.1 - 1.8e-10 41.6 0.0 3.7e-10 40.6 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.11 AII57551.1 - 0.18 10.0 0.1 0.38 9.0 0.1 1.5 1 1 0 1 1 1 0 Firmicute fructose-1,6-bisphosphatase RrnaAD PF00398.20 AII57552.1 - 1.1e-54 185.3 0.0 1.3e-54 185.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 AII57552.1 - 9.9e-05 23.0 0.0 0.00017 22.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AII57552.1 - 0.0053 17.4 0.0 0.01 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 AII57552.1 - 0.023 14.3 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) PCMT PF01135.19 AII57552.1 - 0.027 14.2 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DREV PF05219.12 AII57552.1 - 0.051 12.7 0.0 0.078 12.1 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase HTH_10 PF04967.12 AII57552.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain Acyl-CoA_dh_N PF02771.16 AII57552.1 - 0.15 12.8 0.0 0.36 11.5 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain Methyltransf_31 PF13847.6 AII57552.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 AII57552.1 - 0.19 11.6 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FbpA PF05833.11 AII57552.1 - 0.19 10.4 0.0 0.57 8.9 0.0 1.6 2 0 0 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) GHMP_kinases_C PF08544.13 AII57553.1 - 5.5e-09 36.3 0.0 1.2e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 AII57553.1 - 2.6e-06 27.6 0.1 1.6e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain Rubrerythrin PF02915.17 AII57554.1 - 4.5e-23 82.2 7.7 2.4e-21 76.6 7.7 2.0 1 1 0 1 1 1 1 Rubrerythrin DZR PF12773.7 AII57554.1 - 0.0066 16.5 0.5 0.011 15.8 0.5 1.3 1 0 0 1 1 1 1 Double zinc ribbon zf-P11 PF03854.14 AII57554.1 - 0.0077 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 P-11 zinc finger RecR PF02132.15 AII57554.1 - 0.016 14.8 0.7 0.056 13.0 0.7 1.9 1 1 0 1 1 1 0 RecR protein zf-C3HC4_3 PF13920.6 AII57554.1 - 0.022 14.6 0.1 0.033 14.1 0.1 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ferritin PF00210.24 AII57554.1 - 0.026 14.5 1.4 0.035 14.1 1.0 1.4 1 1 0 1 1 1 0 Ferritin-like domain zf-C3HC4_2 PF13923.6 AII57554.1 - 0.088 12.7 0.5 0.14 12.0 0.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ogr_Delta PF04606.12 AII57554.1 - 0.093 12.7 1.7 5.9 6.9 0.4 2.6 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zinc_ribbon_2 PF13240.6 AII57554.1 - 0.13 12.0 1.2 0.24 11.2 1.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-RING_5 PF14634.6 AII57554.1 - 0.14 12.1 0.6 0.22 11.5 0.6 1.3 1 0 0 1 1 1 0 zinc-RING finger domain Ribosomal_L37e PF01907.19 AII57554.1 - 0.18 12.0 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L37e zf-ribbon_3 PF13248.6 AII57554.1 - 0.2 11.1 3.2 0.37 10.3 0.6 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 AII57554.1 - 0.39 10.9 2.4 1.3 9.2 2.4 1.9 1 1 0 1 1 1 0 Zinc ribbon domain zf-RRN7 PF11781.8 AII57554.1 - 0.58 9.9 3.1 10 5.9 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Desulfoferrod_N PF06397.12 AII57554.1 - 0.79 9.4 4.9 0.57 9.9 0.6 2.2 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain Rubredoxin_2 PF18073.1 AII57554.1 - 2.7 7.8 4.5 2.6 7.9 0.3 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-FCS PF06467.14 AII57555.1 - 0.043 13.8 2.4 0.2 11.6 1.3 2.0 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_6 PF13912.6 AII57555.1 - 4.6 7.4 7.8 0.19 11.7 2.3 1.6 2 0 0 2 2 2 0 C2H2-type zinc finger Ion_trans PF00520.31 AII57556.1 - 8.2e-26 90.7 13.2 1e-25 90.4 13.2 1.0 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 AII57556.1 - 1e-15 57.5 3.3 1e-15 57.5 3.3 2.2 3 0 0 3 3 3 1 Ion channel Rad50_zn_hook PF04423.14 AII57556.1 - 0.037 13.9 0.1 0.073 12.9 0.1 1.4 1 0 0 1 1 1 0 Rad50 zinc hook motif Tetraspanin PF00335.20 AII57556.1 - 0.096 12.4 0.2 0.096 12.4 0.2 2.4 2 1 0 2 2 2 0 Tetraspanin family DUF2427 PF10348.9 AII57556.1 - 0.13 12.0 0.2 0.13 12.0 0.2 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF2427) DUF4231 PF14015.6 AII57556.1 - 0.32 11.5 3.7 20 5.7 0.7 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) PolyA_pol PF01743.20 AII57557.1 - 5.5e-25 88.2 0.0 9e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 AII57557.1 - 2.3e-05 24.1 0.2 7.6e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 AII57557.1 - 0.081 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative ABC_tran PF00005.27 AII57558.1 - 5.6e-32 111.1 0.0 7.8e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AII57558.1 - 6.5e-09 36.0 0.7 0.0011 18.8 0.1 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AII57558.1 - 0.0055 17.1 0.0 0.0083 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 AII57558.1 - 0.0069 16.1 0.0 3.5 7.2 0.0 2.1 1 1 1 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 AII57558.1 - 0.0077 16.5 0.2 0.061 13.6 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 AII57558.1 - 0.0086 16.6 0.1 0.016 15.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AII57558.1 - 0.015 15.1 0.2 0.032 14.0 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 AII57558.1 - 0.017 15.6 0.1 0.087 13.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 AII57558.1 - 0.017 14.9 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein SMC_N PF02463.19 AII57558.1 - 0.023 14.1 0.1 4.5 6.6 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_13 PF13166.6 AII57558.1 - 0.063 11.9 0.0 0.13 10.8 0.0 1.4 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 AII57558.1 - 0.085 12.8 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 AII57558.1 - 0.089 12.5 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 AII57558.1 - 0.094 12.6 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain TsaE PF02367.17 AII57558.1 - 0.19 11.8 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC2_membrane PF01061.24 AII57559.1 - 3.8e-24 85.3 26.2 3.8e-24 85.3 26.2 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AII57559.1 - 6e-05 22.3 29.3 6e-05 22.3 29.3 1.7 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_18 PF13238.6 AII57560.1 - 1.3e-11 45.1 0.1 1.7e-11 44.8 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 AII57560.1 - 1.5e-09 38.4 0.0 2.3e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AII57560.1 - 0.0023 18.1 0.0 0.0039 17.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 AII57560.1 - 0.013 15.6 0.1 0.02 15.0 0.1 1.3 1 1 0 1 1 1 0 Shikimate kinase Zeta_toxin PF06414.12 AII57560.1 - 0.018 14.4 0.1 0.023 14.0 0.1 1.5 1 1 0 1 1 1 0 Zeta toxin AAA PF00004.29 AII57560.1 - 0.018 15.5 0.0 0.028 14.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ribosomal_S13 PF00416.22 AII57560.1 - 0.028 14.8 0.2 0.049 14.0 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein S13/S18 cobW PF02492.19 AII57560.1 - 0.072 12.7 0.2 7.3 6.1 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 AII57560.1 - 0.16 10.9 0.5 4.2 6.3 0.1 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB dCMP_cyt_deam_1 PF00383.23 AII57561.1 - 3.8e-26 90.9 1.2 4.8e-26 90.6 1.2 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 AII57561.1 - 2.2e-17 63.1 0.2 2.6e-17 62.8 0.2 1.1 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC_N PF08210.11 AII57561.1 - 0.00018 21.5 0.1 0.00073 19.5 0.1 1.8 1 1 0 1 1 1 1 APOBEC-like N-terminal domain Bd3614-deam PF14439.6 AII57561.1 - 0.036 14.2 1.2 0.08 13.0 0.6 1.8 1 1 1 2 2 2 0 Bd3614-like deaminase NAD1 PF18778.1 AII57561.1 - 0.039 14.1 0.0 0.053 13.6 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 AII57561.1 - 0.046 13.8 0.0 0.067 13.2 0.0 1.2 1 0 0 1 1 1 0 APOBEC2 SNAD4 PF18750.1 AII57561.1 - 0.046 13.8 0.1 0.068 13.3 0.1 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 AII57561.1 - 0.11 12.6 0.0 0.19 11.9 0.0 1.4 1 1 0 1 1 1 0 APOBEC3 DAGK_cat PF00781.24 AII57562.1 - 3.8e-30 104.1 0.0 5.8e-30 103.5 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Peptidase_C10 PF01640.17 AII57562.1 - 0.094 13.0 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase C10 family dUTPase PF00692.19 AII57563.1 - 4.3e-10 39.4 0.0 7e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 dUTPase DCD PF06559.11 AII57563.1 - 0.0022 16.8 0.0 0.0022 16.8 0.0 1.1 1 0 0 1 1 1 1 2'-deoxycytidine 5'-triphosphate deaminase (DCD) zf-trcl PF13451.6 AII57564.1 - 2.5e-26 91.3 11.8 1.2e-25 89.1 2.8 3.0 3 0 0 3 3 3 1 Probable zinc-ribbon domain Lar_restr_allev PF14354.6 AII57564.1 - 0.00013 22.2 10.0 0.0047 17.3 1.2 3.0 2 1 1 3 3 3 2 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.10 AII57564.1 - 0.00059 19.9 15.3 0.14 12.3 4.3 2.7 2 1 0 2 2 2 2 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 AII57564.1 - 0.0031 17.0 8.5 0.13 11.8 1.3 3.5 3 1 0 3 3 3 2 TFIIB zinc-binding DZR PF12773.7 AII57564.1 - 0.0081 16.2 11.0 2.7 8.1 11.0 2.6 1 1 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 AII57564.1 - 0.012 15.6 7.4 0.034 14.2 0.5 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_6 PF14599.6 AII57564.1 - 0.016 15.2 8.8 2.8 8.0 0.0 3.7 3 1 1 4 4 4 0 Zinc-ribbon LIM PF00412.22 AII57564.1 - 0.13 12.5 4.6 1 9.7 2.1 2.5 2 1 0 2 2 2 0 LIM domain DUF2318 PF10080.9 AII57564.1 - 0.23 11.6 6.2 5.2 7.3 0.1 2.6 2 1 1 3 3 3 0 Predicted membrane protein (DUF2318) Jiv90 PF14901.6 AII57564.1 - 0.31 11.2 3.5 1.4 9.1 1.9 2.0 1 1 1 2 2 2 0 Cleavage inducing molecular chaperone Zn_Tnp_IS1595 PF12760.7 AII57564.1 - 0.43 10.6 14.3 45 4.1 10.2 3.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain DNA_RNApol_7kD PF03604.13 AII57564.1 - 0.53 10.0 9.5 3.2 7.5 1.1 3.5 3 1 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Cys_rich_CPXG PF14255.6 AII57564.1 - 1.2 9.1 7.1 0.39 10.7 1.4 2.6 3 1 0 3 3 3 0 Cysteine-rich CPXCG zf-RING_5 PF14634.6 AII57564.1 - 1.2 9.1 8.9 1.2 9.2 0.9 3.0 2 2 0 2 2 2 0 zinc-RING finger domain Rubredoxin_2 PF18073.1 AII57564.1 - 2.2 8.0 14.0 9.3 6.1 0.1 3.8 4 0 0 4 4 4 0 Rubredoxin metal binding domain zinc_ribbon_9 PF14369.6 AII57564.1 - 2.6 8.4 9.0 12 6.3 0.1 3.6 3 1 1 4 4 4 0 zinc-ribbon zf-C3HC4_3 PF13920.6 AII57564.1 - 2.7 7.9 10.9 2.2 8.2 0.4 3.5 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) OrfB_Zn_ribbon PF07282.11 AII57564.1 - 3.1 7.8 11.1 4.5 7.3 0.9 3.0 2 1 1 3 3 3 0 Putative transposase DNA-binding domain PhnA_Zn_Ribbon PF08274.12 AII57564.1 - 3.4 7.7 0.0 3.4 7.7 0.0 3.2 4 0 0 4 4 3 0 PhnA Zinc-Ribbon zf-Mss51 PF13824.6 AII57564.1 - 3.7 7.7 7.1 37 4.5 4.4 2.9 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 ADD_ATRX PF17981.1 AII57564.1 - 4 7.4 9.1 2.2 8.2 0.1 3.4 4 0 0 4 4 4 0 Cysteine Rich ADD domain zf-RRN7 PF11781.8 AII57564.1 - 5.8 6.7 14.7 11 5.9 0.5 4.0 4 0 0 4 4 4 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-RING_4 PF14570.6 AII57564.1 - 7.1 6.5 14.2 4.2 7.3 5.1 3.2 2 2 0 2 2 2 0 RING/Ubox like zinc-binding domain ABC_tran PF00005.27 AII57565.1 - 2e-38 132.0 0.0 2.7e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AII57565.1 - 3.9e-13 49.9 0.0 1.6e-05 24.8 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AII57565.1 - 5.9e-09 35.7 0.6 1.2e-07 31.4 0.6 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AII57565.1 - 1.4e-06 29.0 0.0 4.3e-06 27.4 0.0 1.6 1 1 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 AII57565.1 - 3.8e-06 26.0 0.5 0.094 11.5 0.0 3.0 2 1 0 2 2 2 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 AII57565.1 - 5.4e-06 26.9 0.0 7.6e-06 26.4 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AII57565.1 - 1.9e-05 25.0 0.1 8.8e-05 22.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AII57565.1 - 2.3e-05 24.0 0.0 4.8e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATPase_2 PF01637.18 AII57565.1 - 2.7e-05 24.2 0.1 8.1e-05 22.6 0.1 1.9 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea Rad17 PF03215.15 AII57565.1 - 0.00025 21.0 0.0 0.00033 20.6 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 AII57565.1 - 0.00038 20.4 0.1 0.0011 18.9 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_15 PF13175.6 AII57565.1 - 0.00042 20.1 0.0 0.0067 16.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 AII57565.1 - 0.00046 20.0 0.1 0.0012 18.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AII57565.1 - 0.00059 20.4 0.0 0.001 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 AII57565.1 - 0.0022 18.3 0.5 0.034 14.4 0.1 2.6 1 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 AII57565.1 - 0.0042 17.3 0.3 0.0094 16.1 0.3 1.9 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 AII57565.1 - 0.01 16.1 1.0 0.16 12.2 0.3 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 AII57565.1 - 0.014 15.1 0.0 0.042 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 AII57565.1 - 0.021 14.8 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 AII57565.1 - 0.021 15.3 0.5 0.38 11.2 0.2 2.7 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 AII57565.1 - 0.024 14.2 0.1 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain CobU PF02283.16 AII57565.1 - 0.026 14.1 0.1 0.49 9.9 0.0 2.3 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase ATPase PF06745.13 AII57565.1 - 0.027 13.8 0.1 0.076 12.3 0.0 1.6 2 0 0 2 2 2 0 KaiC IstB_IS21 PF01695.17 AII57565.1 - 0.033 13.9 0.0 0.088 12.5 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein MMR_HSR1 PF01926.23 AII57565.1 - 0.036 14.1 0.1 0.064 13.4 0.1 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.19 AII57565.1 - 0.043 13.4 0.1 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 AII57565.1 - 0.051 13.9 0.1 0.082 13.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.15 AII57565.1 - 0.052 12.3 0.1 0.11 11.3 0.0 1.6 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_14 PF13173.6 AII57565.1 - 0.056 13.5 0.0 0.12 12.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 AII57565.1 - 0.061 12.5 0.1 0.081 12.1 0.1 1.4 1 1 0 1 1 1 0 NB-ARC domain AAA_27 PF13514.6 AII57565.1 - 0.088 12.4 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 AII57565.1 - 0.12 12.6 0.0 0.35 11.1 0.0 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_13 PF13166.6 AII57565.1 - 0.12 11.0 0.0 4.3 5.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 AII57565.1 - 0.13 12.3 0.0 0.6 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) BPD_transp_1 PF00528.22 AII57566.1 - 1.9e-25 89.7 10.4 1.9e-25 89.7 10.4 2.0 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Tetraspanin PF00335.20 AII57566.1 - 4.5 6.9 6.9 10 5.8 6.9 1.5 1 0 0 1 1 1 0 Tetraspanin family SBP_bac_3 PF00497.20 AII57567.1 - 2e-61 207.3 2.3 2.4e-61 207.0 2.3 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 AII57567.1 - 5.3e-08 33.0 0.1 2.6e-06 27.6 0.0 2.5 2 1 0 2 2 2 1 Ligated ion channel L-glutamate- and glycine-binding site DUF4969 PF16339.5 AII57567.1 - 0.0069 16.7 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4969) NMT1 PF09084.11 AII57567.1 - 0.021 14.8 1.4 0.033 14.1 0.3 1.9 2 1 0 2 2 2 0 NMT1/THI5 like PEARLI-4 PF05278.12 AII57567.1 - 0.061 12.9 0.0 0.093 12.3 0.0 1.2 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) TarH PF02203.15 AII57567.1 - 0.071 13.0 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Tar ligand binding domain homologue DegV PF02645.16 AII57568.1 - 3.7e-79 266.0 0.0 4.1e-79 265.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein, DegV family COG1307 Dak1_2 PF13684.6 AII57568.1 - 5.7e-06 25.6 0.0 6e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Dihydroxyacetone kinase family CorA PF01544.18 AII57569.1 - 9.2e-74 248.4 1.5 1.2e-73 248.0 1.5 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2207 PF09972.9 AII57569.1 - 0.029 13.2 0.1 0.041 12.6 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1664 PF07889.12 AII57569.1 - 0.095 12.7 1.7 7 6.7 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) SLATT_5 PF18160.1 AII57569.1 - 0.2 11.0 1.2 0.38 10.1 1.2 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 EMP70 PF02990.16 AII57569.1 - 0.2 10.3 2.2 0.31 9.6 2.2 1.2 1 0 0 1 1 1 0 Endomembrane protein 70 Vut_1 PF02592.15 AII57570.1 - 9.3e-46 155.9 7.3 1.4e-45 155.3 7.3 1.3 1 0 0 1 1 1 1 Putative vitamin uptake transporter Lactamase_B_2 PF12706.7 AII57571.1 - 4e-16 59.1 0.0 5.4e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 AII57571.1 - 0.0001 22.4 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Mut7-C PF01927.16 AII57572.1 - 9.6e-42 142.5 0.0 1.1e-41 142.3 0.0 1.0 1 0 0 1 1 1 1 Mut7-C RNAse domain DUF5615 PF18480.1 AII57572.1 - 0.0084 15.8 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5615) PIN_10 PF18478.1 AII57572.1 - 0.034 14.3 0.0 0.26 11.5 0.0 2.2 1 1 0 1 1 1 0 PIN like domain Carb_kinase PF01256.17 AII57573.1 - 6e-57 192.9 0.3 8.4e-57 192.4 0.3 1.2 1 0 0 1 1 1 1 Carbohydrate kinase YjeF_N PF03853.15 AII57573.1 - 5e-38 130.7 0.2 5e-38 130.7 0.2 1.7 2 0 0 2 2 2 1 YjeF-related protein N-terminus Shikimate_DH PF01488.20 AII57573.1 - 0.0051 16.9 0.0 0.064 13.3 0.0 2.6 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Pan_kinase PF03309.14 AII57574.1 - 6.3e-67 225.4 0.1 7.5e-67 225.2 0.1 1.1 1 0 0 1 1 1 1 Type III pantothenate kinase PTS_EIIC PF02378.18 AII57574.1 - 0.013 14.5 0.2 0.018 14.1 0.2 1.2 1 0 0 1 1 1 0 Phosphotransferase system, EIIC FtsA PF14450.6 AII57574.1 - 0.044 14.2 0.2 0.48 10.9 0.2 2.5 1 1 0 1 1 1 0 Cell division protein FtsA DFP PF04127.15 AII57575.1 - 2.1e-62 210.3 0.7 6.5e-62 208.7 0.0 2.0 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein Flavoprotein PF02441.19 AII57575.1 - 5.2e-43 146.5 0.6 8.7e-43 145.8 0.6 1.3 1 0 0 1 1 1 1 Flavoprotein NAD_binding_10 PF13460.6 AII57575.1 - 0.0054 16.6 0.1 0.016 15.1 0.1 1.9 2 0 0 2 2 2 1 NAD(P)H-binding FMN_red PF03358.15 AII57575.1 - 0.008 15.9 0.0 0.083 12.6 0.0 2.3 2 0 0 2 2 2 1 NADPH-dependent FMN reductase F420_oxidored PF03807.17 AII57575.1 - 0.13 12.8 0.4 2.9 8.5 0.1 2.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF1724 PF08350.10 AII57575.1 - 0.17 12.0 0.0 0.45 10.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1724) tRNA-synt_1 PF00133.22 AII57576.1 - 1.4e-203 677.5 0.1 2e-201 670.4 0.1 2.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 AII57576.1 - 5.8e-36 123.8 0.1 1e-35 122.9 0.1 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 AII57576.1 - 2.3e-24 85.9 0.0 2.1e-09 36.6 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) Val_tRNA-synt_C PF10458.9 AII57576.1 - 6.9e-12 45.5 5.4 6.9e-12 45.5 5.4 1.8 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1_2 PF13603.6 AII57576.1 - 2.5e-09 36.9 0.0 3.4e-07 30.0 0.0 2.4 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 AII57576.1 - 0.0069 15.8 0.0 0.64 9.3 0.0 3.1 2 1 1 3 3 3 1 tRNA synthetases class I (C) catalytic domain DivIC PF04977.15 AII57576.1 - 0.011 15.5 0.2 0.027 14.3 0.2 1.7 1 0 0 1 1 1 0 Septum formation initiator ABC_tran_CTD PF16326.5 AII57576.1 - 0.022 15.0 2.5 0.022 15.0 2.5 2.0 2 0 0 2 2 2 0 ABC transporter C-terminal domain tRNA-synt_1f PF01921.18 AII57576.1 - 0.03 13.3 0.0 0.052 12.4 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) tRNA-synt_1c PF00749.21 AII57576.1 - 0.11 11.4 0.1 2.1 7.2 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain ADIP PF11559.8 AII57576.1 - 0.17 12.0 0.6 0.27 11.3 0.6 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TF_Zn_Ribbon PF08271.12 AII57576.1 - 0.53 9.8 2.8 2.1 7.9 0.1 2.9 3 0 0 3 3 3 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 AII57576.1 - 0.83 9.8 8.0 2.3 8.4 2.6 3.1 3 0 0 3 3 3 0 Zinc ribbon domain TPR_MLP1_2 PF07926.12 AII57576.1 - 1.9 8.6 4.6 0.89 9.6 2.1 1.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF5082 PF16888.5 AII57576.1 - 6.9 7.0 5.9 11 6.3 2.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) HisKA_3 PF07730.13 AII57577.1 - 7.8e-13 48.8 3.9 7.8e-13 48.8 3.9 2.3 2 0 0 2 2 2 1 Histidine kinase PAS PF00989.25 AII57577.1 - 6.2e-12 45.5 0.1 2e-11 43.9 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 AII57577.1 - 1.1e-10 41.7 0.0 2.7e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 AII57577.1 - 1.8e-09 37.8 0.0 3.4e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold HATPase_c PF02518.26 AII57577.1 - 7.2e-08 32.9 0.1 1.8e-07 31.6 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 AII57577.1 - 9.9e-08 31.8 0.0 4.5e-07 29.7 0.0 2.1 1 1 0 1 1 1 1 PAS domain PAS_3 PF08447.12 AII57577.1 - 0.0004 20.6 0.0 0.00074 19.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold HATPase_c_2 PF13581.6 AII57577.1 - 0.00044 20.2 0.0 0.001 19.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PAS_7 PF12860.7 AII57577.1 - 0.0059 16.8 0.3 0.014 15.5 0.2 1.8 1 1 0 1 1 1 1 PAS fold H-kinase_dim PF02895.14 AII57577.1 - 0.012 15.9 2.3 1.6 9.2 0.3 2.8 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain PAS_12 PF18095.1 AII57577.1 - 0.057 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 UPF0242 C-terminal PAS-like domain DUF1678 PF07913.11 AII57577.1 - 0.13 12.0 0.2 0.21 11.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) Response_reg PF00072.24 AII57578.1 - 1e-29 103.0 0.3 2.1e-29 102.0 0.1 1.6 2 0 0 2 2 2 1 Response regulator receiver domain GerE PF00196.19 AII57578.1 - 9.5e-20 69.9 0.2 1.7e-19 69.1 0.2 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 AII57578.1 - 7.3e-06 25.6 0.0 1.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AII57578.1 - 0.00027 20.4 0.1 0.00058 19.3 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_40 PF14493.6 AII57578.1 - 0.0011 19.4 0.1 0.011 16.2 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 AII57578.1 - 0.0011 18.7 0.0 0.0025 17.6 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain DUF742 PF05331.11 AII57578.1 - 0.0017 18.2 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF742) HTH_38 PF13936.6 AII57578.1 - 0.0017 18.1 0.2 0.0047 16.7 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_ECF PF07638.11 AII57578.1 - 0.0026 17.7 0.1 0.0042 17.0 0.1 1.5 1 0 0 1 1 1 1 ECF sigma factor HTH_29 PF13551.6 AII57578.1 - 0.017 15.1 0.0 0.045 13.8 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix HTH_24 PF13412.6 AII57578.1 - 0.039 13.5 0.1 0.082 12.5 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 AII57578.1 - 0.049 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 HTH domain HTH_10 PF04967.12 AII57578.1 - 0.063 13.1 0.1 0.87 9.4 0.1 2.5 1 1 0 1 1 1 0 HTH DNA binding domain Mic1 PF07035.12 AII57578.1 - 0.1 12.3 0.1 13 5.5 0.0 2.2 2 0 0 2 2 2 0 Colon cancer-associated protein Mic1-like SAM_2 PF07647.17 AII57579.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SecA_DEAD PF07517.14 AII57580.1 - 1.1e-125 418.8 0.0 1.1e-123 412.2 0.0 2.6 2 1 0 2 2 2 1 SecA DEAD-like domain SecA_SW PF07516.13 AII57580.1 - 4.8e-58 196.5 1.0 4.8e-58 196.5 1.0 3.2 3 0 0 3 3 3 1 SecA Wing and Scaffold domain SecA_PP_bind PF01043.20 AII57580.1 - 1.2e-35 122.5 0.0 4.2e-35 120.8 0.0 2.0 1 0 0 1 1 1 1 SecA preprotein cross-linking domain SEC-C PF02810.15 AII57580.1 - 4.4e-10 39.3 14.7 7.7e-10 38.5 14.7 1.4 1 0 0 1 1 1 1 SEC-C motif Helicase_C PF00271.31 AII57580.1 - 0.0054 17.1 1.4 0.024 15.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Tht1 PF04163.12 AII57580.1 - 0.062 12.1 1.1 0.14 10.9 1.1 1.5 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein DEAD PF00270.29 AII57580.1 - 0.067 13.0 0.4 3.4 7.4 0.0 3.1 3 0 0 3 3 3 0 DEAD/DEAH box helicase DUF1090 PF06476.12 AII57580.1 - 0.29 11.3 6.5 0.61 10.2 2.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) AAR2 PF05282.11 AII57580.1 - 0.37 10.2 1.6 2.5 7.4 0.0 2.3 2 0 0 2 2 2 0 AAR2 protein ISG65-75 PF11727.8 AII57580.1 - 4.9 6.3 8.2 1.1 8.4 4.6 1.7 2 0 0 2 2 2 0 Invariant surface glycoprotein Pribosyltran_N PF13793.6 AII57581.1 - 1.4e-47 160.4 0.1 6.3e-47 158.3 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 AII57581.1 - 1.2e-24 87.3 1.0 7.4e-22 78.3 0.2 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 AII57581.1 - 2.3e-08 33.7 0.7 1.9e-07 30.8 0.5 2.3 3 0 0 3 3 3 1 Phosphoribosyl transferase domain SHMT PF00464.19 AII57582.1 - 1.5e-161 537.5 0.2 1.8e-161 537.2 0.2 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 AII57582.1 - 2.2e-11 43.5 0.0 3e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 AII57582.1 - 7.8e-08 31.9 0.2 1.2e-07 31.3 0.2 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 AII57582.1 - 0.0039 15.8 0.0 0.0056 15.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme UDG PF03167.19 AII57583.1 - 3e-45 154.0 0.0 3.9e-45 153.6 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily RNase_J_C PF17770.1 AII57584.1 - 1.2e-17 64.7 0.0 2.8e-17 63.5 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease J C-terminal domain Lactamase_B PF00753.27 AII57584.1 - 1.8e-14 54.2 0.1 4.4e-14 52.9 0.1 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AII57584.1 - 1.8e-13 50.5 0.1 3.5e-12 46.3 0.0 2.4 2 1 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.12 AII57584.1 - 4.1e-13 49.0 2.3 1.3e-11 44.3 0.1 3.0 3 0 0 3 3 3 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_6 PF16661.5 AII57584.1 - 0.006 16.0 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 AII57584.1 - 0.0066 16.4 0.1 0.076 12.9 0.0 2.3 2 0 0 2 2 2 1 Beta-lactamase superfamily domain FtsK_SpoIIIE PF01580.18 AII57585.1 - 2.2e-53 181.1 0.5 1.8e-39 135.6 0.0 2.2 1 1 1 2 2 2 2 FtsK/SpoIIIE family FtsK_alpha PF17854.1 AII57585.1 - 9.5e-29 99.5 0.1 3e-28 97.9 0.1 1.9 1 1 0 1 1 1 1 FtsK alpha domain FtsK_gamma PF09397.10 AII57585.1 - 4.4e-13 48.8 0.0 1.7e-12 46.9 0.0 2.0 2 0 0 2 2 2 1 Ftsk gamma domain AAA_10 PF12846.7 AII57585.1 - 9e-08 31.4 0.0 0.00065 18.7 0.0 2.1 2 0 0 2 2 2 2 AAA-like domain TniB PF05621.11 AII57585.1 - 0.00017 21.0 0.3 1.8 7.9 0.1 3.3 3 0 0 3 3 3 2 Bacterial TniB protein T2SSE PF00437.20 AII57585.1 - 0.00033 19.8 0.0 0.00056 19.1 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Adeno_IVa2 PF02456.15 AII57585.1 - 0.0061 15.4 0.1 0.0097 14.7 0.1 1.2 1 0 0 1 1 1 1 Adenovirus IVa2 protein DUF87 PF01935.17 AII57585.1 - 0.013 15.6 0.1 0.025 14.7 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_22 PF13401.6 AII57585.1 - 0.013 15.7 0.1 0.048 13.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 AII57585.1 - 0.017 14.1 0.0 0.11 11.4 0.0 1.9 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 AII57585.1 - 0.017 15.0 0.0 0.082 12.8 0.0 1.9 1 1 0 1 1 1 0 NACHT domain ResIII PF04851.15 AII57585.1 - 0.019 15.0 0.0 0.1 12.6 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 AII57585.1 - 0.025 14.9 0.2 0.096 13.0 0.2 1.9 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 AII57585.1 - 0.048 13.4 0.2 0.14 11.9 0.2 1.8 1 1 0 1 1 1 0 DEAD/DEAH box helicase Voltage_CLC PF00654.20 AII57585.1 - 0.13 11.5 9.4 0.21 10.8 9.4 1.2 1 0 0 1 1 1 0 Voltage gated chloride channel DUF853 PF05872.12 AII57585.1 - 0.14 10.7 0.0 0.24 9.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF3188 PF11384.8 AII57585.1 - 6.3 6.6 6.5 13 5.6 1.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) UvrB_inter PF17757.1 AII57587.1 - 1.8e-34 117.7 0.1 5.6e-34 116.2 0.1 1.9 1 0 0 1 1 1 1 UvrB interaction domain UvrB PF12344.8 AII57587.1 - 2.7e-21 75.1 2.8 5.8e-21 74.1 2.8 1.6 1 0 0 1 1 1 1 Ultra-violet resistance protein B Helicase_C PF00271.31 AII57587.1 - 3.2e-17 62.9 0.1 2.1e-16 60.3 0.0 2.4 2 1 1 3 3 3 1 Helicase conserved C-terminal domain UVR PF02151.19 AII57587.1 - 3.6e-10 39.2 2.8 3.6e-10 39.2 2.8 3.5 5 0 0 5 5 4 1 UvrB/uvrC motif ResIII PF04851.15 AII57587.1 - 2.2e-09 37.6 0.0 2.9e-08 33.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 AII57587.1 - 0.00063 19.6 0.6 0.012 15.4 0.0 3.2 2 1 0 4 4 4 1 DEAD/DEAH box helicase AAA_19 PF13245.6 AII57587.1 - 0.0068 16.8 0.3 20 5.5 0.4 4.0 3 1 0 3 3 3 0 AAA domain AAA_30 PF13604.6 AII57587.1 - 0.01 15.5 0.0 0.48 10.1 0.0 2.8 3 0 0 3 3 3 0 AAA domain Kinesin PF00225.23 AII57587.1 - 0.012 14.6 0.0 0.022 13.7 0.0 1.4 1 0 0 1 1 1 0 Kinesin motor domain Microtub_bd PF16796.5 AII57587.1 - 0.018 15.0 0.0 0.084 12.8 0.0 2.0 2 0 0 2 2 2 0 Microtubule binding UvrD-helicase PF00580.21 AII57587.1 - 0.025 14.1 3.8 2.6 7.5 0.0 3.1 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain SPOUT_MTase_2 PF14419.6 AII57587.1 - 0.074 12.4 1.0 0.29 10.5 0.1 2.4 3 0 0 3 3 3 0 AF2226-like SPOUT RNA Methylase fused to THUMP AAA_22 PF13401.6 AII57587.1 - 0.095 13.0 0.2 2.5 8.4 0.0 3.3 3 1 1 4 4 4 0 AAA domain SWI2_SNF2 PF18766.1 AII57587.1 - 0.1 12.3 0.0 1.1 8.9 0.0 2.6 3 0 0 3 3 3 0 SWI2/SNF2 ATPase OmpH PF03938.14 AII57587.1 - 0.16 12.3 7.6 0.92 9.8 0.1 2.8 3 0 0 3 3 2 0 Outer membrane protein (OmpH-like) DUF87 PF01935.17 AII57587.1 - 0.31 11.1 2.1 0.76 9.8 0.1 2.5 2 1 0 2 2 2 0 Helicase HerA, central domain Nnf1 PF03980.14 AII57587.1 - 3.5 8.0 7.2 2.4 8.5 0.3 3.0 3 0 0 3 3 3 0 Nnf1 HHH_5 PF14520.6 AII57588.1 - 7.2e-19 68.2 3.8 2.2e-18 66.6 0.6 2.9 3 0 0 3 3 3 1 Helix-hairpin-helix domain RuvA_N PF01330.21 AII57588.1 - 2e-18 66.2 0.0 2.7e-17 62.6 0.0 2.3 2 0 0 2 2 2 1 RuvA N terminal domain RuvA_C PF07499.13 AII57588.1 - 2.9e-11 43.6 0.7 6.7e-11 42.5 0.7 1.7 1 0 0 1 1 1 1 RuvA, C-terminal domain HHH PF00633.23 AII57588.1 - 8.7e-07 28.5 5.2 0.00069 19.4 0.1 4.2 4 1 0 4 4 4 2 Helix-hairpin-helix motif Transposase_20 PF02371.16 AII57588.1 - 9.4e-05 22.6 0.1 0.0049 17.1 0.0 2.6 2 0 0 2 2 2 1 Transposase IS116/IS110/IS902 family HHH_3 PF12836.7 AII57588.1 - 0.0019 18.4 0.1 0.12 12.7 0.0 2.8 1 1 0 2 2 2 1 Helix-hairpin-helix motif HHH_2 PF12826.7 AII57588.1 - 0.0099 16.0 0.0 1.2 9.3 0.0 2.7 1 1 1 2 2 2 1 Helix-hairpin-helix motif IMS_HHH PF11798.8 AII57588.1 - 0.015 15.6 0.1 1 9.9 0.0 2.9 3 0 0 3 3 3 0 IMS family HHH motif HHH_8 PF14716.6 AII57588.1 - 0.016 15.6 1.7 0.12 12.8 0.1 2.8 2 1 1 3 3 3 0 Helix-hairpin-helix domain RuvC PF02075.17 AII57589.1 - 3.7e-46 156.7 0.1 4.2e-46 156.5 0.1 1.0 1 0 0 1 1 1 1 Crossover junction endodeoxyribonuclease RuvC Transcrip_reg PF01709.20 AII57590.1 - 3.1e-89 298.6 0.2 3.4e-89 298.4 0.2 1.0 1 0 0 1 1 1 1 Transcriptional regulator RTX PF02382.15 AII57590.1 - 0.015 15.0 0.1 0.022 14.4 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain in RTX protein ACPS PF01648.20 AII57591.1 - 4.2e-16 59.1 0.0 4.8e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 AII57591.1 - 0.0017 18.4 0.1 0.078 13.1 0.1 2.2 2 0 0 2 2 2 2 4'-phosphopantetheinyl transferase N-terminal domain 2Fe-2S_thioredx PF01257.19 AII57592.1 - 1.1e-44 151.8 0.0 1.2e-44 151.7 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Carboxyl_trans PF01039.22 AII57593.1 - 2.2e-188 626.9 2.4 2.5e-188 626.7 2.4 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 AII57593.1 - 0.002 17.6 4.8 0.027 13.9 0.1 2.3 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) Aconitase PF00330.20 AII57594.1 - 5.3e-94 315.8 0.7 1.8e-91 307.4 0.7 2.4 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) DUF521 PF04412.13 AII57594.1 - 0.00032 19.6 0.0 0.00046 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF521) DUF3880 PF12996.7 AII57594.1 - 0.13 12.3 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 DUF based on E. rectale Gene description (DUF3880) DUF2620 PF10941.8 AII57594.1 - 1.1 9.4 3.6 1.4 9.1 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function DUF2620 Aconitase_C PF00694.19 AII57595.1 - 7.4e-15 55.4 0.0 1.1e-14 54.9 0.0 1.2 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.13 AII57595.1 - 9.2e-08 32.0 0.0 5.9e-06 26.1 0.0 2.1 1 1 0 1 1 1 1 Aconitate hydratase 2 N-terminus Iso_dh PF00180.20 AII57596.1 - 1.9e-113 379.2 0.0 2.1e-113 379.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ldh_1_N PF00056.23 AII57597.1 - 1.9e-40 138.2 0.4 2.7e-40 137.7 0.4 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 AII57597.1 - 1.4e-24 86.9 0.1 4.1e-24 85.4 0.0 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain F420_oxidored PF03807.17 AII57597.1 - 0.00034 21.1 1.3 0.0026 18.3 1.3 2.5 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Glyco_hydro_4 PF02056.16 AII57597.1 - 0.0037 16.8 0.0 0.011 15.2 0.0 1.8 2 0 0 2 2 2 1 Family 4 glycosyl hydrolase NAD_Gly3P_dh_N PF01210.23 AII57597.1 - 0.039 13.9 0.3 0.23 11.4 0.1 2.3 1 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 AII57597.1 - 0.043 13.9 0.2 0.12 12.4 0.2 1.9 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 AII57597.1 - 0.051 13.5 0.2 0.1 12.5 0.2 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MIT PF04212.18 AII57598.1 - 0.0067 16.5 2.2 0.016 15.2 0.5 2.4 1 1 2 3 3 3 1 MIT (microtubule interacting and transport) domain YscO PF07321.12 AII57598.1 - 0.035 14.1 0.3 0.044 13.8 0.3 1.2 1 0 0 1 1 1 0 Type III secretion protein YscO Peptidase_M75 PF09375.10 AII57598.1 - 0.042 13.3 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Imelysin PTS_IIA PF02255.16 AII57598.1 - 0.15 12.1 0.8 1.4 9.1 0.1 2.1 1 1 1 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit Fumerase PF05681.14 AII57599.1 - 3.9e-103 344.6 0.1 4.4e-103 344.4 0.1 1.0 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Fumerase_C PF05683.12 AII57600.1 - 2.2e-60 203.5 0.0 2.4e-60 203.4 0.0 1.0 1 0 0 1 1 1 1 Fumarase C-terminus HIT PF01230.23 AII57601.1 - 3.2e-30 104.7 0.0 3.6e-30 104.6 0.0 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 AII57601.1 - 4.2e-23 82.0 0.0 4.7e-23 81.8 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CDH PF02611.15 AII57601.1 - 0.031 13.9 0.1 0.19 11.3 0.1 1.9 1 1 0 1 1 1 0 CDP-diacylglycerol pyrophosphatase CwfJ_C_1 PF04677.15 AII57601.1 - 0.17 11.8 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 NUDIX PF00293.28 AII57602.1 - 4.6e-15 55.8 0.0 1e-14 54.7 0.0 1.5 1 1 1 2 2 2 1 NUDIX domain Acetyltransf_1 PF00583.25 AII57603.1 - 1.2e-09 38.4 0.0 1.5e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 AII57603.1 - 8.2e-07 29.4 0.0 1.1e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AII57603.1 - 7.9e-06 25.8 0.0 1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AII57603.1 - 0.025 14.7 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_6 PF13480.7 AII57603.1 - 0.036 14.2 0.0 0.047 13.8 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 AII57603.1 - 0.054 13.5 0.0 0.11 12.5 0.0 1.6 1 1 0 1 1 1 0 FR47-like protein NAD_kinase PF01513.21 AII57604.1 - 2.7e-51 174.5 0.0 7.2e-51 173.1 0.0 1.6 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 AII57604.1 - 0.0019 17.8 0.0 0.0031 17.1 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain PDH PF02153.17 AII57606.1 - 2.7e-38 131.5 0.0 3.1e-38 131.3 0.0 1.0 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 AII57606.1 - 1.4e-12 48.0 0.0 4e-12 46.6 0.0 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 AII57606.1 - 3.9e-07 30.4 0.0 5.7e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 AII57606.1 - 0.00015 21.7 1.8 0.036 14.0 0.4 2.6 2 1 1 3 3 3 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 AII57606.1 - 0.00025 20.7 0.2 0.0019 17.9 0.0 2.4 2 1 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Semialdhyde_dh PF01118.24 AII57606.1 - 0.033 14.6 0.0 0.36 11.3 0.0 2.4 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 AII57606.1 - 0.044 13.7 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding 3HCDH_N PF02737.18 AII57606.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 AII57606.1 - 0.049 13.0 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 AII57606.1 - 0.11 13.3 0.0 0.26 12.1 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold IlvN PF07991.12 AII57606.1 - 0.17 11.4 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain UDPG_MGDP_dh_C PF03720.15 AII57606.1 - 0.18 12.3 0.0 0.44 11.0 0.0 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain PDT PF00800.18 AII57607.1 - 3.5e-62 209.5 0.0 4.9e-62 209.0 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydratase CM_2 PF01817.21 AII57607.1 - 1.4e-19 70.2 1.5 3.8e-19 68.8 1.5 1.8 1 0 0 1 1 1 1 Chorismate mutase type II ACT PF01842.25 AII57607.1 - 1.3e-06 28.1 0.0 3.6e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 ACT domain DUF948 PF06103.11 AII57607.1 - 0.073 13.3 0.5 0.23 11.7 0.4 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Chorismate_synt PF01264.21 AII57608.1 - 1.4e-130 434.8 0.1 1.5e-130 434.7 0.1 1.0 1 0 0 1 1 1 1 Chorismate synthase EPSP_synthase PF00275.20 AII57609.1 - 2.1e-98 329.8 0.0 2.5e-98 329.5 0.0 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) SKI PF01202.22 AII57610.1 - 9.3e-43 146.1 0.1 1.1e-42 145.9 0.1 1.0 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 AII57610.1 - 4.8e-06 27.1 1.0 1.3e-05 25.7 0.7 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AII57610.1 - 1e-05 25.7 0.1 8.2e-05 22.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 AII57610.1 - 0.0012 18.7 1.6 0.041 13.7 0.0 2.5 1 1 1 2 2 2 1 Deoxynucleoside kinase AAA_17 PF13207.6 AII57610.1 - 0.0053 17.2 0.4 0.017 15.5 0.3 2.0 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 AII57610.1 - 0.0076 16.0 1.0 0.13 12.0 0.1 2.3 1 1 0 2 2 2 1 Cytidylate kinase AAA_22 PF13401.6 AII57610.1 - 0.0077 16.5 0.7 0.052 13.8 0.2 2.2 1 1 1 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.6 AII57610.1 - 0.011 15.8 0.1 0.025 14.7 0.1 1.7 1 1 1 2 2 2 0 Cytidylate kinase-like family SRPRB PF09439.10 AII57610.1 - 0.019 14.4 0.2 0.031 13.7 0.2 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 AII57610.1 - 0.022 15.1 0.0 0.025 15.0 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 AII57610.1 - 0.034 14.1 0.2 0.058 13.4 0.2 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 AII57610.1 - 0.13 12.5 0.2 0.29 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 AII57610.1 - 0.13 12.7 0.1 0.3 11.5 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 AII57610.1 - 0.2 12.1 0.7 0.27 11.7 0.7 1.6 1 1 0 1 1 1 0 ABC transporter Thymidylate_kin PF02223.17 AII57610.1 - 0.24 11.0 2.2 6 6.5 0.4 2.5 1 1 2 3 3 3 0 Thymidylate kinase Shikimate_dh_N PF08501.11 AII57611.1 - 3.6e-28 97.6 0.1 8.2e-28 96.5 0.1 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 AII57611.1 - 3.8e-12 45.8 1.3 6.1e-12 45.1 1.3 1.3 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 AII57611.1 - 8.1e-06 25.9 0.0 1.4e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 AII57611.1 - 0.0004 20.9 0.0 0.0026 18.3 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 AII57611.1 - 0.0006 20.1 0.1 0.0038 17.5 0.1 2.2 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 AII57611.1 - 0.094 12.2 0.2 3.8 6.9 0.1 2.3 2 0 0 2 2 2 0 short chain dehydrogenase DHquinase_I PF01487.15 AII57612.1 - 9.7e-54 183.0 0.0 1.2e-53 182.8 0.0 1.0 1 0 0 1 1 1 1 Type I 3-dehydroquinase DHQ_synthase PF01761.20 AII57613.1 - 5e-96 320.9 0.0 6e-96 320.6 0.0 1.0 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 AII57613.1 - 2.2e-12 47.2 0.2 1.9e-11 44.2 0.2 1.9 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 AII57613.1 - 3.4e-07 29.4 0.0 3.6e-05 22.8 0.0 2.2 2 1 0 2 2 2 2 Iron-containing alcohol dehydrogenase DAHP_synth_1 PF00793.20 AII57614.1 - 1.4e-62 211.1 0.0 1.8e-62 210.7 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family DAHP_snth_FXD PF18152.1 AII57614.1 - 7.2e-17 61.0 0.0 1.5e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 DAHP synthase ferredoxin-like domain NeuB PF03102.14 AII57614.1 - 7.4e-06 25.6 0.0 0.0071 15.8 0.0 2.2 2 0 0 2 2 2 2 NeuB family Ribosom_S12_S23 PF00164.25 AII57615.1 - 9.5e-39 131.5 0.2 1.3e-38 131.1 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S7 PF00177.21 AII57616.1 - 9.9e-60 200.5 7.2 1.1e-59 200.4 7.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e ATC_hydrolase PF14196.6 AII57616.1 - 0.031 15.1 7.2 1.8 9.3 0.1 2.1 1 1 1 2 2 2 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase Mak_N_cap PF18085.1 AII57616.1 - 0.06 14.4 0.0 1.5 9.9 0.0 2.3 2 0 0 2 2 2 0 Maltokinase N-terminal cap domain GTP_EFTU PF00009.27 AII57617.1 - 5.2e-65 218.6 0.0 7.5e-65 218.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 AII57617.1 - 1.6e-40 137.6 0.7 3.5e-40 136.5 0.7 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 AII57617.1 - 1.7e-32 111.4 0.0 4.3e-32 110.0 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 AII57617.1 - 1.4e-30 105.2 0.1 3e-30 104.1 0.1 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 AII57617.1 - 2.7e-11 43.7 0.0 6.6e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 AII57617.1 - 2.3e-06 27.4 0.0 4.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain AIG1 PF04548.16 AII57617.1 - 0.00071 19.0 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 AII57617.1 - 0.0047 17.0 0.1 0.011 15.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Methyltransf_3 PF01596.17 AII57617.1 - 0.013 14.7 0.1 0.028 13.6 0.1 1.5 1 0 0 1 1 1 0 O-methyltransferase AvrPtoB_bdg PF16847.5 AII57617.1 - 0.042 14.3 0.0 0.23 11.9 0.0 2.2 2 0 0 2 2 2 0 Avirulence AvrPtoB, BAK1-binding domain Ribosomal_S10 PF00338.22 AII57618.1 - 3.1e-34 117.1 0.1 3.5e-34 116.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Ribosomal_L3 PF00297.22 AII57619.1 - 3.7e-17 62.4 10.7 2.4e-15 56.4 2.3 3.2 1 1 2 3 3 3 3 Ribosomal protein L3 Ribosomal_L4 PF00573.22 AII57620.1 - 1.7e-67 226.9 0.2 1.9e-67 226.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_L23 PF00276.20 AII57621.1 - 2.9e-26 91.6 0.6 3.2e-26 91.5 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L23 Ribosomal_L2_C PF03947.18 AII57622.1 - 2.9e-49 166.5 2.4 6.2e-49 165.4 2.4 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 AII57622.1 - 5.1e-32 109.7 0.4 9.7e-32 108.8 0.4 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain RsgI_N PF12791.7 AII57622.1 - 0.033 14.1 0.0 1.6 8.7 0.0 2.4 2 0 0 2 2 2 0 Anti-sigma factor N-terminus Ribosomal_S19 PF00203.21 AII57623.1 - 7.5e-31 105.9 0.1 8.6e-31 105.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19 DUF1442 PF07279.11 AII57623.1 - 0.007 15.7 0.0 0.0077 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1442) Ribosomal_L22 PF00237.19 AII57624.1 - 3.5e-27 94.6 1.1 3.8e-27 94.5 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF5304 PF17230.2 AII57624.1 - 0.076 13.2 0.3 0.46 10.7 0.1 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5304) Ribosomal_S3_C PF00189.20 AII57625.1 - 1.6e-34 118.2 1.7 1.6e-34 118.2 1.7 1.8 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 AII57625.1 - 1.9e-17 62.9 2.8 3.8e-17 61.9 2.8 1.6 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 AII57625.1 - 2.7e-05 23.9 0.7 5.8e-05 22.9 0.7 1.6 1 0 0 1 1 1 1 KH domain Ribosomal_L16 PF00252.18 AII57626.1 - 3.4e-48 163.0 1.2 3.9e-48 162.8 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_L29 PF00831.23 AII57627.1 - 2.3e-19 69.1 3.4 2.6e-19 68.9 3.4 1.0 1 0 0 1 1 1 1 Ribosomal L29 protein Ribosomal_S17 PF00366.20 AII57628.1 - 1.5e-28 98.6 1.7 2.1e-28 98.2 1.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_L14 PF00238.19 AII57629.1 - 3e-53 179.1 1.0 3.3e-53 178.9 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e ribosomal_L24 PF17136.4 AII57630.1 - 1.2e-25 89.7 2.5 2.8e-25 88.5 0.2 1.9 2 0 0 2 2 2 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 AII57630.1 - 2.6e-07 30.4 0.4 3.9e-07 29.8 0.4 1.3 1 0 0 1 1 1 1 KOW motif HNH PF01844.23 AII57630.1 - 0.0097 16.1 2.3 0.022 14.9 0.1 2.2 2 0 0 2 2 2 1 HNH endonuclease HNH_5 PF14279.6 AII57630.1 - 0.38 10.6 5.3 1.3 8.9 0.4 2.2 1 1 1 2 2 2 0 HNH endonuclease Baculo_LEF5_C PF11792.8 AII57630.1 - 2.2 8.0 4.8 21 4.9 0.2 2.3 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain Ribosomal_L5_C PF00673.21 AII57631.1 - 2.2e-35 120.7 0.0 3.2e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 AII57631.1 - 8.7e-26 90.0 0.9 1.7e-25 89.1 0.9 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 DUF5503 PF17607.2 AII57631.1 - 0.012 15.9 0.0 0.03 14.6 0.0 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5503) Ribosomal_S14 PF00253.21 AII57632.1 - 3.7e-24 84.2 5.3 4.5e-24 84.0 5.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF2797 PF10977.8 AII57632.1 - 0.029 14.3 0.3 0.034 14.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) Ribosomal_S8 PF00410.19 AII57633.1 - 2.7e-48 163.1 0.0 3e-48 162.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_L6 PF00347.23 AII57634.1 - 3.2e-36 123.8 6.3 8e-18 64.9 0.2 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Cuticle_1 PF08140.11 AII57634.1 - 0.061 13.4 0.1 0.19 11.8 0.1 1.8 1 0 0 1 1 1 0 Crustacean cuticle protein repeat Ribosomal_L18p PF00861.22 AII57635.1 - 4.8e-43 146.2 0.8 5.5e-43 146.0 0.8 1.0 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Ribosomal_S5 PF00333.20 AII57636.1 - 2.2e-26 91.6 2.9 2.2e-26 91.6 2.9 1.6 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 AII57636.1 - 1e-25 88.9 0.9 1.6e-25 88.4 0.9 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain DUF1515 PF07439.11 AII57636.1 - 0.039 14.0 0.1 0.071 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Ribosomal_L30 PF00327.20 AII57637.1 - 3.9e-18 65.1 0.1 4.4e-18 64.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L27A PF00828.19 AII57638.1 - 2.2e-33 115.6 0.2 3e-33 115.2 0.2 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L18 PF17135.4 AII57638.1 - 0.0096 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e SecY PF00344.20 AII57639.1 - 1.2e-94 317.1 20.1 1.4e-94 316.8 20.1 1.1 1 0 0 1 1 1 1 SecY translocase DUF3667 PF12412.8 AII57639.1 - 0.22 11.0 4.6 0.53 9.8 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3667) DUF2537 PF10801.8 AII57639.1 - 7.1 6.9 13.3 4.1 7.7 1.9 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2537) ADK PF00406.22 AII57640.1 - 1.3e-48 164.9 0.0 1.6e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 AII57640.1 - 9.7e-22 77.9 0.1 1.9e-21 76.9 0.0 1.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 AII57640.1 - 1.2e-07 32.3 0.0 2e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 AII57640.1 - 3.3e-05 23.8 6.0 0.00011 22.1 6.0 2.0 1 1 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 AII57640.1 - 0.00012 22.3 0.0 0.00021 21.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 AII57640.1 - 0.0086 16.2 0.0 2.8 8.0 0.0 2.2 2 0 0 2 2 2 2 Shikimate kinase RuvB_N PF05496.12 AII57640.1 - 0.029 14.1 0.0 0.075 12.8 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Cytidylate_kin PF02224.18 AII57640.1 - 0.087 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase PPR_2 PF13041.6 AII57640.1 - 0.19 12.0 0.0 0.44 10.8 0.0 1.6 1 0 0 1 1 1 0 PPR repeat family Peptidase_M24 PF00557.24 AII57641.1 - 5.1e-52 176.6 0.3 5.7e-52 176.4 0.3 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF4926 PF16277.5 AII57641.1 - 0.041 13.3 1.0 0.13 11.7 1.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4926) ATP-cone PF03477.16 AII57641.1 - 0.088 13.4 0.0 0.5 11.0 0.0 2.0 2 0 0 2 2 2 0 ATP cone domain eIF-1a PF01176.19 AII57642.1 - 1.3e-28 98.6 0.0 1.4e-28 98.5 0.0 1.0 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Prot_ATP_ID_OB PF16450.5 AII57642.1 - 0.027 14.4 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain Peptidase_S24 PF00717.23 AII57642.1 - 0.029 14.3 0.0 0.03 14.3 0.0 1.1 1 0 0 1 1 1 0 Peptidase S24-like RNase_II_C_S1 PF18614.1 AII57642.1 - 0.04 13.9 0.2 0.2 11.6 0.2 1.9 1 1 0 1 1 1 0 RNase II-type exonuclease C-terminal S1 domain RsgA_N PF16745.5 AII57642.1 - 0.047 13.5 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 RsgA N-terminal domain S1 PF00575.23 AII57642.1 - 0.087 13.2 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 S1 RNA binding domain Ribosom_S12_S23 PF00164.25 AII57642.1 - 0.099 12.3 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S12/S23 Ribosomal_L36 PF00444.18 AII57643.1 - 4.2e-19 68.4 10.0 4.6e-19 68.3 10.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L36 Ribosomal_S13 PF00416.22 AII57644.1 - 3.6e-34 117.9 3.5 1.2e-32 113.0 3.5 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 AII57644.1 - 0.0018 17.1 0.0 0.0019 17.0 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) S1-like PF14444.6 AII57644.1 - 0.094 12.7 0.0 0.22 11.5 0.0 1.6 2 0 0 2 2 2 0 S1-like PduV-EutP PF10662.9 AII57644.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Ribosomal_S11 PF00411.19 AII57645.1 - 3e-48 162.8 1.3 3.7e-48 162.5 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 ELFV_dehydrog PF00208.21 AII57645.1 - 0.014 15.1 0.1 0.049 13.3 0.1 1.7 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF2188 PF09954.9 AII57645.1 - 0.016 15.4 0.5 0.032 14.4 0.5 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) Ribosomal_L18p PF00861.22 AII57645.1 - 0.071 13.5 0.1 0.11 12.9 0.1 1.4 1 1 0 1 1 1 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Ribosomal_S4 PF00163.19 AII57646.1 - 5.8e-20 72.0 0.1 1.4e-19 70.8 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 AII57646.1 - 3.1e-19 68.4 0.1 4.9e-19 67.8 0.1 1.3 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 AII57646.1 - 0.04 13.7 0.1 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 S4 domain RNA_pol_A_CTD PF03118.15 AII57647.1 - 5.9e-21 74.0 0.3 1.5e-20 72.7 0.0 1.8 2 0 0 2 2 2 1 Bacterial RNA polymerase, alpha chain C terminal domain RNA_pol_L PF01193.24 AII57647.1 - 9.1e-20 69.9 0.1 3.1e-19 68.2 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_A_bac PF01000.26 AII57647.1 - 2.7e-16 59.9 0.0 5.3e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain DUF2325 PF10087.9 AII57647.1 - 0.082 13.0 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) Ribosomal_L17 PF01196.19 AII57648.1 - 9.1e-34 116.2 0.0 1.1e-33 116.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L17 Phage_TAC_7 PF10109.9 AII57648.1 - 0.11 12.6 0.1 0.24 11.5 0.0 1.6 2 0 0 2 2 2 0 Phage tail assembly chaperone proteins, E, or 41 or 14 PseudoU_synth_1 PF01416.20 AII57649.1 - 9.3e-36 122.6 0.0 3.2e-22 79.0 0.0 2.6 2 1 1 3 3 3 2 tRNA pseudouridine synthase Ribosomal_L13 PF00572.18 AII57650.1 - 4.3e-51 172.4 0.0 4.9e-51 172.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 DUF3659 PF12396.8 AII57650.1 - 0.099 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) Ribosomal_S9 PF00380.19 AII57651.1 - 1.5e-40 138.5 1.2 1.7e-40 138.3 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DUF202 PF02656.15 AII57652.1 - 2.2e-06 28.0 3.1 6.6e-06 26.5 3.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF202) DUF981 PF06168.11 AII57652.1 - 0.003 17.5 2.2 0.0036 17.3 2.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF981) AveC_like PF17198.4 AII57652.1 - 0.048 13.1 0.3 0.12 11.8 0.3 1.7 1 1 0 1 1 1 0 Spirocyclase AveC-like Cytochrom_B561 PF03188.16 AII57652.1 - 0.055 13.6 0.1 0.064 13.4 0.1 1.0 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 SLATT_5 PF18160.1 AII57652.1 - 0.058 12.7 1.6 0.065 12.6 1.6 1.0 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 TauE PF01925.19 AII57652.1 - 0.061 12.9 3.1 0.066 12.8 3.1 1.0 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE Jagunal PF07086.12 AII57652.1 - 0.063 13.3 0.1 0.071 13.2 0.1 1.1 1 0 0 1 1 1 0 Jagunal, ER re-organisation during oogenesis CBP4 PF07960.11 AII57652.1 - 0.066 13.1 0.1 0.087 12.7 0.1 1.1 1 0 0 1 1 1 0 CBP4 Gram_pos_anchor PF00746.21 AII57652.1 - 2.3 8.2 3.8 24 5.0 0.2 2.2 2 0 0 2 2 2 0 LPXTG cell wall anchor motif bact-PGI_C PF10432.9 AII57653.1 - 1.9e-46 157.9 0.0 6e-45 153.0 0.0 2.3 2 0 0 2 2 2 1 Bacterial phospho-glucose isomerase C-terminal SIS domain SIS PF01380.22 AII57653.1 - 2.3e-07 30.7 0.1 0.00034 20.5 0.0 2.6 2 0 0 2 2 2 2 SIS domain PGM_PMM_I PF02878.16 AII57654.1 - 2.3e-38 131.0 0.1 4.2e-38 130.2 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 AII57654.1 - 7.7e-24 84.3 0.0 1.4e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 AII57654.1 - 6.4e-22 77.9 0.0 1.3e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 AII57654.1 - 9.4e-13 48.2 0.0 2.3e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Adipogenin PF15202.6 AII57655.1 - 0.25 11.4 1.8 0.2 11.7 1.0 1.4 1 1 1 2 2 2 0 Adipogenin Herpes_LMP1 PF05297.11 AII57655.1 - 0.52 9.4 3.1 0.61 9.2 3.1 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF1700 PF08006.11 AII57655.1 - 0.86 9.1 9.1 0.9 9.0 9.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF5326 PF17260.2 AII57655.1 - 1.5 9.0 9.9 5.5 7.2 9.9 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5326) Oleosin PF01277.17 AII57655.1 - 5.3 6.8 12.1 5.9 6.7 12.1 1.1 1 0 0 1 1 1 0 Oleosin S-AdoMet_synt_C PF02773.16 AII57656.1 - 2e-65 218.9 0.0 8.8e-65 216.9 0.0 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 AII57656.1 - 3.2e-47 159.7 0.0 7.1e-47 158.6 0.0 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 AII57656.1 - 2.5e-43 146.8 0.2 1.1e-42 144.7 0.1 2.0 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 AII57656.1 - 0.11 11.3 0.3 0.36 9.6 0.1 1.8 2 0 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) AdoHcyase PF05221.17 AII57657.1 - 1e-62 212.0 0.0 2.6e-32 112.2 0.0 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 AII57657.1 - 9.6e-53 178.6 0.1 1.4e-52 178.0 0.1 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 AII57657.1 - 1.8e-09 37.2 0.1 3.8e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 AII57657.1 - 9.1e-09 35.1 0.1 2e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 AII57657.1 - 0.078 12.3 1.1 0.17 11.2 1.1 1.6 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 AII57657.1 - 0.66 9.8 2.7 2.5 8.0 0.9 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AAA_33 PF13671.6 AII57658.1 - 6.6e-25 87.9 0.0 1.1e-24 87.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 AII57658.1 - 6.4e-10 38.6 0.0 1e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 AII57658.1 - 1.8e-05 25.3 0.0 5.4e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 AII57658.1 - 2.6e-05 24.7 0.0 4.8e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 AII57658.1 - 0.00038 20.6 0.1 0.00087 19.5 0.1 1.5 1 0 0 1 1 1 1 Cytidylate kinase-like family KTI12 PF08433.10 AII57658.1 - 0.0021 17.5 0.0 0.0047 16.4 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 APH PF01636.23 AII57658.1 - 0.0064 16.4 0.0 0.016 15.2 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family dNK PF01712.19 AII57658.1 - 0.0096 15.8 0.0 0.041 13.7 0.0 1.9 1 1 1 2 2 2 1 Deoxynucleoside kinase ADK PF00406.22 AII57658.1 - 0.011 15.8 0.0 0.037 14.1 0.0 1.8 2 0 0 2 2 2 0 Adenylate kinase Viral_helicase1 PF01443.18 AII57658.1 - 0.045 13.5 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase tRNA_lig_kinase PF08303.11 AII57658.1 - 0.14 12.2 0.3 0.55 10.3 0.3 2.0 1 1 0 1 1 1 0 tRNA ligase kinase domain SepF PF04472.12 AII57658.1 - 0.17 12.2 0.0 0.54 10.6 0.0 1.8 1 0 0 1 1 1 0 Cell division protein SepF PNP_UDP_1 PF01048.20 AII57661.1 - 1.3e-47 162.0 0.0 1.6e-47 161.8 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily NIBRIN_BRCT_II PF16508.5 AII57661.1 - 0.2 12.0 0.0 0.34 11.3 0.0 1.3 1 0 0 1 1 1 0 Second BRCT domain on Nijmegen syndrome breakage protein IF-2B PF01008.17 AII57662.1 - 1.2e-85 287.2 0.1 1.3e-85 287.0 0.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family ABC2_membrane_3 PF12698.7 AII57663.1 - 1.4e-39 136.2 20.3 1.7e-39 135.9 20.3 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 AII57663.1 - 1.3e-27 96.6 18.9 4e-24 85.2 15.2 2.2 2 0 0 2 2 2 2 ABC-2 type transporter ABC2_membrane_2 PF12679.7 AII57663.1 - 4.6e-14 52.4 1.7 9.7e-14 51.3 1.7 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein RepA_N PF06970.11 AII57663.1 - 0.052 13.5 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Replication initiator protein A (RepA) N-terminus Smim3 PF17307.2 AII57663.1 - 0.12 11.9 0.4 19 4.9 0.0 2.5 2 0 0 2 2 2 0 Small integral membrane protein 3 DUF5423 PF17461.2 AII57663.1 - 0.16 10.8 0.3 0.22 10.3 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5423) ABC_tran PF00005.27 AII57664.1 - 1.4e-29 103.3 0.0 2.9e-29 102.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AII57664.1 - 1.3e-12 48.2 0.5 1e-08 35.4 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AII57664.1 - 4.1e-06 26.8 0.3 0.089 12.5 0.0 2.6 2 1 1 3 3 3 2 AAA ATPase domain DUF4162 PF13732.6 AII57664.1 - 8.4e-05 23.2 0.1 0.00018 22.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) AAA_23 PF13476.6 AII57664.1 - 0.00016 22.2 0.0 0.00028 21.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 AII57664.1 - 0.00041 19.9 0.1 0.033 13.6 0.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AII57664.1 - 0.00073 19.2 0.0 0.0018 18.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_7 PF12775.7 AII57664.1 - 0.0017 17.9 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_27 PF13514.6 AII57664.1 - 0.0046 16.6 0.1 0.0092 15.6 0.0 1.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 AII57664.1 - 0.0073 16.2 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 AII57664.1 - 0.027 14.9 0.1 0.27 11.6 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 AII57664.1 - 0.029 14.1 0.0 9.8 5.9 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein Rad17 PF03215.15 AII57664.1 - 0.04 13.8 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_16 PF13191.6 AII57664.1 - 0.049 14.0 0.0 0.08 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain CLP1_P PF16575.5 AII57664.1 - 0.054 13.3 0.1 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop MMR_HSR1 PF01926.23 AII57664.1 - 0.063 13.4 0.1 0.11 12.6 0.1 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase SRP54 PF00448.22 AII57664.1 - 0.088 12.4 0.2 0.32 10.6 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 AII57664.1 - 0.098 11.9 0.0 6.1 6.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.17 AII57664.1 - 0.11 12.5 0.1 0.34 11.0 0.0 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain MaoC_dehydrat_N PF13452.6 AII57665.1 - 3.2e-12 46.7 0.0 1.7e-11 44.3 0.0 1.8 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase MaoC_dehydratas PF01575.19 AII57666.1 - 5.6e-13 48.5 0.0 7.1e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 AII57666.1 - 0.0014 18.7 0.0 0.0018 18.4 0.0 1.2 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase Acetyltransf_3 PF13302.7 AII57667.1 - 4.2e-20 72.8 0.0 6e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AII57667.1 - 2.2e-09 37.6 0.0 2.7e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 AII57667.1 - 5.7e-08 32.6 0.0 1e-07 31.7 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AII57667.1 - 0.00099 19.5 0.2 0.0015 18.9 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AII57667.1 - 0.0022 18.2 0.0 0.0025 18.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Serpulina_VSP PF05540.11 AII57667.1 - 0.054 12.5 0.1 0.066 12.3 0.1 1.1 1 0 0 1 1 1 0 Serpulina hyodysenteriae variable surface protein HEAT_2 PF13646.6 AII57668.1 - 8.1e-28 96.7 1.1 1.2e-12 48.0 0.1 4.2 1 1 2 4 4 4 3 HEAT repeats HEAT PF02985.22 AII57668.1 - 4e-13 48.4 0.3 0.012 15.8 0.0 5.5 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 AII57668.1 - 6.8e-08 32.8 0.4 0.038 14.5 0.0 4.7 4 1 1 5 5 5 2 HEAT-like repeat Cnd1 PF12717.7 AII57668.1 - 0.00039 20.5 0.0 0.66 10.0 0.0 3.7 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 AII57668.1 - 0.00055 18.6 0.0 0.0014 17.3 0.0 1.7 1 1 0 1 1 1 1 Adaptin N terminal region Vitellogenin_N PF01347.22 AII57668.1 - 0.00095 17.7 0.0 4.1 5.7 0.0 3.0 1 1 1 3 3 3 3 Lipoprotein amino terminal region HEAT_PBS PF03130.16 AII57668.1 - 0.0029 18.1 4.4 5 8.1 0.0 5.6 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat Arm PF00514.23 AII57668.1 - 0.0068 16.4 0.2 0.59 10.3 0.0 3.1 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat IFRD PF05004.13 AII57668.1 - 0.021 14.0 0.7 0.15 11.2 0.1 2.3 2 1 0 2 2 2 0 Interferon-related developmental regulator (IFRD) Proteasom_PSMB PF10508.9 AII57668.1 - 0.071 11.6 0.2 2.6 6.5 0.0 2.7 2 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit PAC2 PF09754.9 AII57669.1 - 3.7e-45 154.6 0.1 4.3e-45 154.3 0.1 1.0 1 0 0 1 1 1 1 PAC2 family Fe_dep_repr_C PF02742.15 AII57669.1 - 0.18 11.9 0.2 0.43 10.7 0.2 1.5 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain PmbA_TldD PF01523.16 AII57670.1 - 2.9e-51 174.9 0.0 3.9e-51 174.6 0.0 1.1 1 0 0 1 1 1 1 Putative modulator of DNA gyrase PmbA_TldD PF01523.16 AII57671.1 - 1.1e-53 182.9 0.2 1.5e-53 182.4 0.2 1.2 1 0 0 1 1 1 1 Putative modulator of DNA gyrase PGM_PMM_I PF02878.16 AII57672.1 - 7.1e-29 100.3 0.0 1.7e-28 99.0 0.0 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 AII57672.1 - 5.5e-24 84.8 0.0 1.6e-23 83.2 0.0 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 AII57672.1 - 2.2e-17 63.3 0.0 3.7e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 AII57672.1 - 6e-11 42.4 0.0 2.6e-10 40.3 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain CinA_KH PF18146.1 AII57672.1 - 0.059 13.5 0.0 2.6 8.3 0.0 2.4 2 0 0 2 2 2 0 Damage-inducible protein CinA KH domain NTP_transferase PF00483.23 AII57673.1 - 8.8e-37 127.0 0.0 1.1e-36 126.7 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 AII57673.1 - 5e-24 83.1 31.1 1e-09 37.7 0.9 5.1 3 1 3 6 6 6 5 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 AII57673.1 - 1.1e-14 55.1 0.0 1.3e-14 54.8 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 AII57673.1 - 4.7e-13 48.6 24.2 2e-10 40.3 3.0 5.1 5 1 0 5 5 5 3 Hexapeptide repeat of succinyl-transferase IspD PF01128.19 AII57673.1 - 1.5e-05 24.8 0.0 2.2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DUF4954 PF16314.5 AII57673.1 - 0.00063 18.0 0.3 0.0012 17.1 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 AII57673.1 - 0.19 10.6 0.3 0.52 9.2 0.2 1.7 1 1 0 1 1 1 0 L-fucokinase NTP_transferase PF00483.23 AII57674.1 - 2.2e-38 132.3 0.0 2.8e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 AII57674.1 - 5.7e-15 56.0 0.0 7.1e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 AII57674.1 - 6.9e-13 47.8 22.1 1.6e-07 30.7 2.1 4.9 2 1 3 5 5 5 4 Bacterial transferase hexapeptide (six repeats) IspD PF01128.19 AII57674.1 - 0.0002 21.2 0.0 0.00036 20.3 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Hexapep_2 PF14602.6 AII57674.1 - 0.00021 21.0 4.6 0.00021 21.0 4.6 4.1 3 1 1 5 5 5 3 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 AII57674.1 - 0.023 12.8 3.3 0.03 12.5 2.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4954) CTP_transf_3 PF02348.19 AII57674.1 - 0.08 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Cytidylyltransferase Glycos_transf_2 PF00535.26 AII57674.1 - 0.083 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 SIS PF01380.22 AII57675.1 - 4.7e-55 185.0 0.4 5.3e-28 97.5 0.1 2.6 3 0 0 3 3 3 2 SIS domain GATase_6 PF13522.6 AII57675.1 - 5.8e-22 78.3 0.0 9.9e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 AII57675.1 - 8.9e-18 64.4 0.0 1.6e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 AII57675.1 - 0.00027 20.0 0.0 0.00041 19.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 AII57675.1 - 0.0011 19.0 0.2 0.021 14.8 0.0 2.7 2 1 1 3 3 3 1 SIS domain PK_C PF02887.16 AII57675.1 - 0.11 12.7 0.1 0.42 10.9 0.1 2.0 2 0 0 2 2 2 0 Pyruvate kinase, alpha/beta domain DUF3700 PF12481.8 AII57675.1 - 0.18 11.2 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Aluminium induced protein Hypoth_Ymh PF09509.10 AII57675.1 - 0.18 11.7 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (Hypoth_ymh) 2-Hacid_dh PF00389.30 AII57675.1 - 0.39 10.4 1.3 2.3 7.9 1.3 2.2 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain PBP PF01161.20 AII57676.1 - 1.4e-34 119.3 0.0 1.6e-34 119.1 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein HAD_2 PF13419.6 AII57677.1 - 6e-23 81.8 0.2 1.5e-22 80.5 0.2 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AII57677.1 - 6.1e-13 49.6 0.0 1.2e-11 45.3 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 AII57677.1 - 2.3e-08 34.0 0.0 4.3e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 AII57677.1 - 0.00066 19.8 0.0 1.4 9.1 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Orn_Arg_deC_N PF02784.16 AII57678.1 - 1.7e-63 214.3 0.0 2.2e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 AII57678.1 - 2e-17 63.2 0.0 2.2e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 AII57678.1 - 0.00012 21.8 0.0 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Integrase_Zn PF02022.19 AII57678.1 - 0.084 12.9 1.5 0.13 12.2 0.2 2.0 2 0 0 2 2 2 0 Integrase Zinc binding domain DNA_pol3_delta2 PF13177.6 AII57679.1 - 3.7e-50 169.9 0.0 1.2e-49 168.2 0.0 1.7 2 1 0 2 2 2 1 DNA polymerase III, delta subunit DNApol3-delta_C PF09115.10 AII57679.1 - 2.2e-05 24.9 1.2 6.2e-05 23.5 1.2 1.8 1 0 0 1 1 1 1 DNA polymerase III, delta subunit, C terminal AAA PF00004.29 AII57679.1 - 0.0015 18.9 0.0 0.0036 17.7 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AII57679.1 - 0.033 14.5 0.0 0.07 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain DNA_pol3_gamma3 PF12169.8 AII57679.1 - 0.055 13.4 1.0 0.11 12.4 1.0 1.4 1 0 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III AAA_5 PF07728.14 AII57679.1 - 0.084 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PSP1 PF04468.12 AII57680.1 - 1.4e-25 89.4 1.3 2.1e-25 88.8 1.3 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region PriA_3primeBD PF17764.1 AII57680.1 - 0.042 13.7 0.1 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 3′ DNA-binding domain (3′BD) FabA PF07977.13 AII57680.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 FabA-like domain HNH PF01844.23 AII57681.1 - 8.8e-14 51.4 3.8 1.5e-13 50.6 3.8 1.4 1 0 0 1 1 1 1 HNH endonuclease HNH_5 PF14279.6 AII57681.1 - 6.2e-12 45.2 0.7 8.9e-12 44.7 0.7 1.2 1 0 0 1 1 1 1 HNH endonuclease HNH_4 PF13395.6 AII57681.1 - 0.0026 17.6 0.0 0.0051 16.7 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease YafQ_toxin PF15738.5 AII57681.1 - 0.056 13.8 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial toxin of type II toxin-antitoxin system, YafQ RRXRR PF14239.6 AII57681.1 - 0.066 13.1 0.0 0.095 12.6 0.0 1.2 1 0 0 1 1 1 0 RRXRR protein zf-CHCC PF10276.9 AII57681.1 - 0.22 11.6 0.2 0.22 11.6 0.2 2.1 2 0 0 2 2 2 0 Zinc-finger domain IstB_IS21 PF01695.17 AII57682.1 - 2.7e-38 131.5 0.0 1.6e-19 70.3 0.0 2.1 2 0 0 2 2 2 2 IstB-like ATP binding protein Bac_DnaA PF00308.18 AII57682.1 - 7e-17 62.0 0.0 1.9e-07 31.1 0.0 2.1 2 0 0 2 2 2 2 Bacterial dnaA protein AAA PF00004.29 AII57682.1 - 4.3e-15 56.3 0.0 6.3e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 AII57682.1 - 5.7e-10 39.5 0.1 0.00016 22.1 0.0 3.3 2 2 0 2 2 2 2 RNA helicase AAA_16 PF13191.6 AII57682.1 - 7.7e-09 36.2 0.0 0.0025 18.2 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain Sigma54_activat PF00158.26 AII57682.1 - 1.9e-08 34.2 0.0 0.0027 17.4 0.0 3.0 2 1 0 2 2 2 2 Sigma-54 interaction domain ATPase_2 PF01637.18 AII57682.1 - 5.3e-07 29.8 0.0 0.04 13.8 0.0 2.6 2 1 0 2 2 2 2 ATPase domain predominantly from Archaea ResIII PF04851.15 AII57682.1 - 5.4e-07 29.8 0.0 0.001 19.1 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit ABC_tran PF00005.27 AII57682.1 - 5.5e-07 30.2 0.0 0.063 13.8 0.0 2.9 2 2 0 2 2 2 2 ABC transporter AAA_22 PF13401.6 AII57682.1 - 6.1e-07 29.8 0.0 0.037 14.3 0.0 2.7 2 1 0 2 2 2 2 AAA domain NACHT PF05729.12 AII57682.1 - 7.3e-07 29.3 3.2 0.019 14.9 0.1 3.9 2 2 1 3 3 3 2 NACHT domain PhoH PF02562.16 AII57682.1 - 1.1e-06 28.3 0.0 0.014 14.9 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein NB-ARC PF00931.22 AII57682.1 - 2.6e-06 26.8 0.0 0.063 12.5 0.0 3.3 2 1 1 3 3 3 2 NB-ARC domain AAA_28 PF13521.6 AII57682.1 - 5.4e-06 26.7 0.0 0.0036 17.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 AII57682.1 - 6.7e-06 26.2 0.0 0.15 12.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 AII57682.1 - 1.4e-05 25.1 0.0 0.24 11.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 AII57682.1 - 1.8e-05 23.9 0.0 0.026 13.6 0.0 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein Torsin PF06309.11 AII57682.1 - 1.9e-05 24.7 0.0 0.011 15.9 0.0 2.3 2 0 0 2 2 2 1 Torsin AAA_33 PF13671.6 AII57682.1 - 2.9e-05 24.2 0.0 0.052 13.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain TsaE PF02367.17 AII57682.1 - 4.7e-05 23.4 0.0 0.12 12.4 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 AII57682.1 - 4.8e-05 22.8 0.0 0.13 11.6 0.0 2.2 2 0 0 2 2 2 2 KaiC Viral_helicase1 PF01443.18 AII57682.1 - 0.00014 21.7 0.0 0.07 12.9 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase PIF1 PF05970.14 AII57682.1 - 0.00018 20.8 0.0 0.24 10.6 0.0 2.4 2 0 0 2 2 2 2 PIF1-like helicase AAA_18 PF13238.6 AII57682.1 - 0.00031 21.3 0.0 0.076 13.6 0.0 2.9 2 2 0 2 2 2 1 AAA domain AAA_30 PF13604.6 AII57682.1 - 0.00056 19.7 0.0 0.14 11.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 AII57682.1 - 0.0009 18.6 0.0 0.18 11.0 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 AII57682.1 - 0.0014 18.1 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region PduV-EutP PF10662.9 AII57682.1 - 0.0018 18.0 0.0 2 8.1 0.0 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Parvo_NS1 PF01057.17 AII57682.1 - 0.002 17.3 0.1 0.11 11.6 0.0 2.4 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 AII57682.1 - 0.0027 17.5 0.0 0.74 9.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 AII57682.1 - 0.0031 17.4 0.0 2.7 7.9 0.0 2.7 3 0 0 3 3 2 1 RsgA GTPase DUF87 PF01935.17 AII57682.1 - 0.0043 17.2 0.9 2.2 8.3 0.0 3.1 1 1 1 2 2 2 1 Helicase HerA, central domain Mg_chelatase PF01078.21 AII57682.1 - 0.0044 16.4 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 AII57682.1 - 0.0048 17.0 0.0 3.7 7.7 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain Roc PF08477.13 AII57682.1 - 0.0052 17.0 0.0 4 7.7 0.0 3.0 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase RuvB_N PF05496.12 AII57682.1 - 0.0053 16.5 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 AII57682.1 - 0.0061 16.3 0.0 0.21 11.3 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_2 PF07724.14 AII57682.1 - 0.0064 16.6 0.0 1.1 9.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.12 AII57682.1 - 0.0075 15.6 0.0 0.49 9.6 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin APS_kinase PF01583.20 AII57682.1 - 0.012 15.5 0.0 0.54 10.1 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase DEAD PF00270.29 AII57682.1 - 0.014 15.2 0.0 0.37 10.6 0.0 2.6 2 1 1 3 3 3 0 DEAD/DEAH box helicase TIP49 PF06068.13 AII57682.1 - 0.015 14.5 0.0 0.4 9.8 0.0 2.2 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_24 PF13479.6 AII57682.1 - 0.02 14.6 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 AII57682.1 - 0.022 15.1 0.0 4.2 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain PTPlike_phytase PF14566.6 AII57682.1 - 0.032 14.4 0.0 1.9 8.6 0.0 2.4 2 0 0 2 2 2 0 Inositol hexakisphosphate AAA_25 PF13481.6 AII57682.1 - 0.045 13.3 0.0 3.1 7.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain CLP1_P PF16575.5 AII57682.1 - 0.083 12.7 0.0 17 5.2 0.0 2.4 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop ArsA_ATPase PF02374.15 AII57682.1 - 0.093 11.9 0.0 2.5 7.2 0.1 2.2 2 0 0 2 2 2 0 Anion-transporting ATPase NTPase_1 PF03266.15 AII57682.1 - 0.099 12.6 0.0 6.9 6.6 0.0 2.9 3 0 0 3 3 3 0 NTPase SRP54 PF00448.22 AII57682.1 - 0.11 12.1 0.0 4.1 7.0 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Kinesin PF00225.23 AII57682.1 - 0.12 11.3 0.0 6.9 5.5 0.0 2.2 2 0 0 2 2 2 0 Kinesin motor domain AAA_23 PF13476.6 AII57682.1 - 0.14 12.7 4.1 4.5 7.7 0.0 3.0 3 1 1 4 4 3 0 AAA domain cobW PF02492.19 AII57682.1 - 0.14 11.7 0.0 11 5.5 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DnaB_2 PF07261.11 AII57683.1 - 3.5e-13 49.1 0.6 7.4e-13 48.0 0.6 1.5 1 0 0 1 1 1 1 Replication initiation and membrane attachment DUF4994 PF16385.5 AII57683.1 - 0.18 11.8 1.6 1.4 8.9 0.2 2.7 2 1 1 3 3 3 0 Domain of unknown function DnaB_C PF03796.15 AII57684.1 - 1.2e-101 339.3 0.1 1.7e-101 338.9 0.1 1.1 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain DnaB PF00772.21 AII57684.1 - 9.9e-29 99.5 0.0 2.7e-28 98.1 0.0 1.8 2 0 0 2 2 2 1 DnaB-like helicase N terminal domain AAA_25 PF13481.6 AII57684.1 - 8e-10 38.6 0.0 1.2e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 AII57684.1 - 2.8e-05 23.6 0.0 0.00013 21.4 0.0 1.9 2 0 0 2 2 2 1 KaiC AAA PF00004.29 AII57684.1 - 0.0042 17.5 0.0 0.042 14.3 0.0 2.2 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 AII57684.1 - 0.032 14.0 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 AII57684.1 - 0.047 12.9 0.0 0.074 12.2 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_28 PF13521.6 AII57684.1 - 0.059 13.6 0.1 0.23 11.7 0.0 2.1 2 1 0 2 2 2 0 AAA domain Hemopexin PF00045.19 AII57684.1 - 0.11 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Hemopexin Ribosomal_L9_C PF03948.14 AII57685.1 - 1.5e-21 76.6 2.2 1.5e-21 76.6 2.2 1.4 2 0 0 2 2 2 1 Ribosomal protein L9, C-terminal domain Ribosomal_L9_N PF01281.19 AII57685.1 - 4.4e-20 71.0 0.1 8.2e-20 70.1 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain YrzO PF14142.6 AII57685.1 - 0.0025 17.7 0.1 0.0046 16.8 0.1 1.4 1 0 0 1 1 1 1 YrzO-like protein Ploopntkinase3 PF18751.1 AII57685.1 - 0.014 15.3 0.2 0.15 11.9 0.1 2.0 1 1 1 2 2 2 0 P-loop Nucleotide Kinase3 DUF1492 PF07374.11 AII57685.1 - 0.016 15.4 0.4 0.03 14.5 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1492) DUF4145 PF13643.6 AII57685.1 - 0.068 13.3 0.2 0.14 12.3 0.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4145) Stathmin PF00836.19 AII57685.1 - 0.13 12.2 7.3 0.24 11.4 4.5 2.0 1 1 1 2 2 2 0 Stathmin family Phage_H_T_join PF05521.11 AII57685.1 - 0.17 12.4 1.4 0.18 12.3 0.1 1.7 2 0 0 2 2 2 0 Phage head-tail joining protein Pyr_redox_2 PF07992.14 AII57686.1 - 1.7e-43 149.0 2.4 1.9e-43 148.8 2.4 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AII57686.1 - 4e-24 85.4 0.9 2e-16 60.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AII57686.1 - 2.8e-12 47.0 2.3 2.3e-09 37.7 0.2 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 AII57686.1 - 4e-08 32.8 0.4 3.8e-06 26.2 0.1 2.5 2 1 1 3 3 3 1 FAD binding domain FAD_oxidored PF12831.7 AII57686.1 - 1.4e-07 31.2 0.2 3.5e-07 30.0 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 AII57686.1 - 1.7e-07 31.2 2.8 8.7e-05 22.3 0.8 2.7 2 1 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 AII57686.1 - 4.1e-07 29.0 1.9 4.2e-05 22.4 0.1 2.8 3 0 0 3 3 3 2 HI0933-like protein Thi4 PF01946.17 AII57686.1 - 1.1e-06 28.1 0.1 2.8e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 AII57686.1 - 2.6e-06 26.8 1.0 0.00078 18.6 0.1 2.8 3 0 0 3 3 3 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 AII57686.1 - 4.2e-06 26.9 0.2 2.2e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 AII57686.1 - 0.00037 20.9 0.4 0.063 13.7 0.1 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 AII57686.1 - 0.00066 19.0 0.4 0.0017 17.6 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 AII57686.1 - 0.0062 15.6 0.2 0.024 13.7 0.3 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein K_oxygenase PF13434.6 AII57686.1 - 0.021 14.0 0.1 2.5 7.2 0.0 2.9 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 AII57686.1 - 0.056 12.3 1.5 0.069 12.0 0.5 1.6 2 0 0 2 2 2 0 Tryptophan halogenase FA_synthesis PF02504.15 AII57687.1 - 9.9e-95 317.3 3.5 1.1e-94 317.1 3.5 1.0 1 0 0 1 1 1 1 Fatty acid synthesis protein PTA_PTB PF01515.19 AII57687.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.5 1 1 0 1 1 1 0 Phosphate acetyl/butaryl transferase PrpR_N PF06506.11 AII57687.1 - 0.074 12.6 0.4 0.93 9.0 0.0 2.7 3 0 0 3 3 3 0 Propionate catabolism activator BcrAD_BadFG PF01869.20 AII57688.1 - 3.2e-47 161.2 0.0 4.1e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family Peptidase_M20 PF01546.28 AII57689.1 - 1.2e-06 28.4 0.1 1.8e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 AII57689.1 - 2.5e-06 27.3 0.1 8e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain UvrA_inter PF17760.1 AII57690.1 - 1.8e-39 134.2 0.2 7.8e-39 132.1 0.2 2.1 2 0 0 2 2 1 1 UvrA interaction domain UvrA_DNA-bind PF17755.1 AII57690.1 - 1.7e-32 112.1 0.0 3.2e-30 104.7 0.0 3.0 4 0 0 4 4 2 1 UvrA DNA-binding domain ABC_tran PF00005.27 AII57690.1 - 1.1e-20 74.6 0.1 2e-09 38.1 0.0 4.5 3 1 0 3 3 3 3 ABC transporter SMC_N PF02463.19 AII57690.1 - 1.2e-08 34.7 0.0 0.12 11.8 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AII57690.1 - 2.2e-08 34.7 0.2 0.016 15.6 0.0 3.8 4 0 0 4 4 3 2 AAA ATPase domain AAA_29 PF13555.6 AII57690.1 - 3.4e-06 26.7 0.2 0.12 12.2 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 AII57690.1 - 3.7e-06 26.6 0.0 0.11 12.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 AII57690.1 - 1.3e-05 25.1 0.0 0.11 12.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 AII57690.1 - 6.1e-05 23.2 0.4 0.58 10.3 0.1 2.8 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 AII57690.1 - 0.00016 22.2 0.3 0.44 11.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 AII57690.1 - 0.00089 19.8 0.0 1.7 9.2 0.1 2.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 AII57690.1 - 0.00092 19.2 0.0 1.1 9.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 AII57690.1 - 0.0014 18.9 0.2 3.4 7.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain DUF2075 PF09848.9 AII57690.1 - 0.0016 17.7 0.2 1.1 8.4 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 AII57690.1 - 0.0017 18.3 0.1 0.31 11.0 0.1 2.4 2 0 0 2 2 2 1 NACHT domain ATPase PF06745.13 AII57690.1 - 0.0022 17.4 0.0 1.1 8.5 0.0 2.4 2 0 0 2 2 2 1 KaiC AAA_15 PF13175.6 AII57690.1 - 0.0026 17.5 0.1 2.6 7.6 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 AII57690.1 - 0.0027 17.6 3.9 0.16 11.7 0.0 3.8 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system APS_kinase PF01583.20 AII57690.1 - 0.007 16.3 0.2 2.1 8.2 0.0 2.8 2 0 0 2 2 2 1 Adenylylsulphate kinase Zn-ribbon_8 PF09723.10 AII57690.1 - 0.0072 16.4 11.7 5 7.3 0.5 4.4 4 0 0 4 4 4 0 Zinc ribbon domain AAA_30 PF13604.6 AII57690.1 - 0.013 15.2 0.0 26 4.5 0.0 3.6 3 0 0 3 3 3 0 AAA domain DnaJ_CXXCXGXG PF00684.19 AII57690.1 - 0.015 15.7 11.9 0.03 14.7 0.7 4.0 4 1 0 4 4 3 0 DnaJ central domain Zeta_toxin PF06414.12 AII57690.1 - 0.021 14.1 0.2 13 5.0 0.0 3.3 4 0 0 4 4 4 0 Zeta toxin Viral_helicase1 PF01443.18 AII57690.1 - 0.033 13.9 0.2 0.68 9.6 0.2 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 AII57690.1 - 0.035 13.2 0.0 7.9 5.5 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_7 PF12775.7 AII57690.1 - 0.046 13.2 0.0 3.9 6.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region NB-ARC PF00931.22 AII57690.1 - 0.05 12.8 0.2 1.4 8.1 0.1 2.6 3 0 0 3 3 3 0 NB-ARC domain cobW PF02492.19 AII57690.1 - 0.063 12.9 0.6 3.6 7.2 0.1 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ogr_Delta PF04606.12 AII57690.1 - 0.12 12.4 0.1 0.32 11.0 0.1 1.8 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger Sigma54_activat PF00158.26 AII57690.1 - 0.12 12.0 0.1 9.8 5.8 0.0 3.1 3 0 0 3 3 2 0 Sigma-54 interaction domain GcpE PF04551.14 AII57690.1 - 0.12 11.4 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 GcpE protein ATPase_2 PF01637.18 AII57690.1 - 0.16 11.8 0.0 5.9 6.7 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 AII57690.1 - 0.17 12.3 0.1 6.1 7.3 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 AII57690.1 - 0.23 11.1 0.8 12 5.6 0.1 3.0 3 0 0 3 3 3 0 AAA domain Zn_Tnp_IS91 PF14319.6 AII57690.1 - 0.51 10.4 1.5 4.3 7.5 0.0 2.7 3 0 0 3 3 2 0 Transposase zinc-binding domain YhfH PF14149.6 AII57690.1 - 0.61 10.1 0.0 0.61 10.1 0.0 4.7 5 1 1 6 6 5 0 YhfH-like protein zf_UBZ PF18439.1 AII57690.1 - 0.99 9.1 2.5 5.9 6.6 0.4 3.0 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger HD PF01966.22 AII57691.1 - 4.9e-08 33.2 0.3 6e-08 32.9 0.3 1.2 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 AII57691.1 - 0.0083 15.6 0.1 0.026 14.0 0.1 1.7 1 1 0 1 1 1 1 HDOD domain DUF2750 PF11042.8 AII57691.1 - 0.061 13.4 0.0 2.4 8.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2750) HTH_3 PF01381.22 AII57692.1 - 4.3e-11 42.7 0.0 4.8e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 AII57692.1 - 6.6e-09 35.7 0.0 7.7e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 AII57692.1 - 1.3e-08 35.1 0.0 1.4e-08 34.9 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AII57692.1 - 9.9e-05 22.7 0.0 0.00012 22.5 0.0 1.1 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 AII57692.1 - 0.00084 18.9 0.1 0.0016 18.0 0.1 1.5 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 AII57692.1 - 0.0012 18.8 0.2 0.0022 17.9 0.2 1.4 1 0 0 1 1 1 1 HTH domain HTH_Crp_2 PF13545.6 AII57692.1 - 0.0061 16.5 0.1 0.0096 15.9 0.1 1.3 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Sigma70_r4 PF04545.16 AII57692.1 - 0.012 15.1 0.2 0.018 14.5 0.2 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_AsnC-type PF13404.6 AII57692.1 - 0.038 13.8 0.2 0.072 12.9 0.2 1.6 1 1 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_38 PF13936.6 AII57692.1 - 0.059 13.1 0.2 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain GntR PF00392.21 AII57692.1 - 0.073 12.7 0.3 0.24 11.1 0.1 1.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family MqsA_antitoxin PF15731.5 AII57692.1 - 0.076 13.1 0.0 0.077 13.1 0.0 1.1 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA MarR_2 PF12802.7 AII57692.1 - 0.084 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_10 PF04967.12 AII57692.1 - 0.099 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain Phage_CI_repr PF07022.13 AII57692.1 - 0.13 12.4 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain AAA_23 PF13476.6 AII57693.1 - 6.2e-23 82.3 0.9 6.2e-23 82.3 0.9 5.3 2 1 1 3 3 3 1 AAA domain SbcCD_C PF13558.6 AII57693.1 - 2.8e-07 30.7 0.0 8.3e-07 29.2 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 AII57693.1 - 5.5e-07 29.2 0.0 5.5e-07 29.2 0.0 2.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AII57693.1 - 8.3e-07 28.7 0.0 1.7e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 AII57693.1 - 0.00011 22.1 0.0 0.00043 20.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AII57693.1 - 0.035 14.0 0.2 0.24 11.3 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase RNA_helicase PF00910.22 AII57693.1 - 0.095 13.1 0.1 0.42 11.0 0.0 2.2 2 0 0 2 2 2 0 RNA helicase TEX12 PF15219.6 AII57693.1 - 0.39 11.1 4.3 2.4 8.5 0.2 3.6 2 1 1 3 3 3 0 Testis-expressed 12 ABC_tran PF00005.27 AII57693.1 - 5.5 7.5 24.4 1.7 9.2 6.7 5.2 2 2 0 2 2 2 0 ABC transporter Sigma70_r3 PF04539.16 AII57694.1 - 4.9e-28 97.0 0.7 4.9e-28 97.0 0.7 4.7 4 0 0 4 4 4 1 Sigma-70 region 3 Sigma70_r4 PF04545.16 AII57694.1 - 1.2e-22 79.2 4.1 2.6e-20 71.7 3.4 3.0 2 0 0 2 2 2 2 Sigma-70, region 4 Sigma70_r2 PF04542.14 AII57694.1 - 2.6e-20 71.9 0.1 5.6e-20 70.9 0.1 1.6 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r1_2 PF00140.20 AII57694.1 - 8.1e-16 57.7 0.2 3e-15 55.9 0.2 2.1 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 Sigma70_r4_2 PF08281.12 AII57694.1 - 0.037 13.7 0.2 0.68 9.6 0.2 3.2 2 1 0 2 2 2 0 Sigma-70, region 4 HTH_25 PF13413.6 AII57694.1 - 0.13 12.1 1.0 1.5 8.7 0.0 3.0 2 0 0 2 2 2 0 Helix-turn-helix domain PolyA_pol_arg_C PF12626.7 AII57694.1 - 0.19 11.8 1.1 2.9 7.9 0.3 2.5 2 0 0 2 2 2 0 Polymerase A arginine-rich C-terminus DUF4633 PF15464.6 AII57694.1 - 0.52 10.5 4.4 0.61 10.3 2.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4633) Toprim_N PF08275.11 AII57695.1 - 3e-38 130.8 0.0 6.3e-38 129.7 0.0 1.6 1 0 0 1 1 1 1 DNA primase catalytic core, N-terminal domain zf-CHC2 PF01807.20 AII57695.1 - 3.6e-27 94.1 0.0 7.4e-27 93.0 0.0 1.5 1 0 0 1 1 1 1 CHC2 zinc finger Toprim_2 PF13155.6 AII57695.1 - 7.7e-16 58.3 0.0 2e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 Toprim-like Toprim_4 PF13662.6 AII57695.1 - 2.1e-15 57.0 0.2 4.4e-15 55.9 0.2 1.6 1 0 0 1 1 1 1 Toprim domain DnaB_bind PF10410.9 AII57695.1 - 4.9e-12 45.9 0.6 3e-11 43.3 0.0 2.6 3 0 0 3 3 3 1 DnaB-helicase binding domain of primase Toprim_3 PF13362.6 AII57695.1 - 1.3e-08 35.1 0.1 2.8e-08 34.0 0.1 1.6 1 0 0 1 1 1 1 Toprim domain Toprim PF01751.22 AII57695.1 - 5.4e-08 33.0 0.1 1.6e-07 31.5 0.1 1.8 1 0 0 1 1 1 1 Toprim domain PRESAN PF09687.10 AII57695.1 - 0.23 12.0 3.7 0.12 12.9 0.8 2.0 2 0 0 2 2 2 0 Plasmodium RESA N-terminal HD_assoc PF13286.6 AII57696.1 - 5.4e-17 62.1 1.3 5.1e-16 59.0 0.5 2.6 3 0 0 3 3 3 1 Phosphohydrolase-associated domain HD PF01966.22 AII57696.1 - 3.8e-15 56.2 1.9 4.9e-15 55.8 0.6 1.9 2 0 0 2 2 2 1 HD domain PPDK_N PF01326.19 AII57697.1 - 6.4e-105 351.0 0.0 1.3e-104 350.0 0.0 1.5 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers_C PF02896.18 AII57697.1 - 2.4e-71 240.3 0.1 3.9e-71 239.6 0.1 1.3 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.23 AII57697.1 - 7.4e-30 102.5 0.9 2.2e-29 101.0 0.9 1.9 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain HpcH_HpaI PF03328.14 AII57697.1 - 0.0025 17.0 0.0 0.0089 15.2 0.0 1.9 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family DNase-RNase PF02577.14 AII57698.1 - 4.7e-45 152.4 0.7 5.7e-45 152.1 0.7 1.1 1 0 0 1 1 1 1 Bifunctional nuclease Lsr2 PF11774.8 AII57698.1 - 0.0062 16.7 0.1 0.009 16.1 0.1 1.4 1 0 0 1 1 1 1 Lsr2 GRDA PF04723.14 AII57698.1 - 0.069 12.9 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 Glycine reductase complex selenoprotein A ATPase_gene1 PF09527.10 AII57699.1 - 4e-14 52.5 11.8 5.1e-14 52.2 11.8 1.1 1 0 0 1 1 1 1 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter PQ-loop PF04193.14 AII57699.1 - 0.013 15.2 0.3 0.013 15.2 0.3 1.6 2 0 0 2 2 2 0 PQ loop repeat LysE PF01810.18 AII57699.1 - 0.091 12.2 3.9 0.097 12.1 3.9 1.0 1 0 0 1 1 1 0 LysE type translocator DUF2207 PF09972.9 AII57699.1 - 0.49 9.1 2.1 0.54 9.0 2.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ATP-synt_A PF00119.20 AII57700.1 - 6.2e-49 166.8 23.8 6.2e-49 166.8 23.8 1.5 2 0 0 2 2 2 1 ATP synthase A chain ATP-synt_C PF00137.21 AII57701.1 - 4.9e-18 65.2 14.8 5.9e-18 65.0 14.8 1.1 1 0 0 1 1 1 1 ATP synthase subunit C ATP-synt_B PF00430.18 AII57702.1 - 1.1e-23 83.8 12.9 1.4e-23 83.4 12.9 1.1 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) T2SSM PF04612.12 AII57702.1 - 0.0019 18.3 0.1 0.0019 18.3 0.1 2.0 1 1 1 2 2 2 1 Type II secretion system (T2SS), protein M Gp-FAR-1 PF05823.12 AII57702.1 - 0.014 15.7 5.8 0.021 15.2 5.8 1.3 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Glypican PF01153.19 AII57702.1 - 0.019 13.8 0.4 0.021 13.7 0.4 1.1 1 0 0 1 1 1 0 Glypican IMPDH PF00478.25 AII57702.1 - 0.26 10.3 4.3 0.33 9.9 4.3 1.0 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain DUF2514 PF10721.9 AII57702.1 - 0.4 10.7 11.3 0.52 10.3 10.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) DUF2229 PF09989.9 AII57702.1 - 0.61 9.7 8.5 1.8 8.1 8.5 1.7 1 1 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Phasin PF05597.11 AII57702.1 - 0.91 9.5 12.5 0.17 11.9 4.2 2.3 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) YtxH PF12732.7 AII57702.1 - 1.4 9.5 13.0 6 7.5 3.8 2.7 1 1 1 2 2 2 0 YtxH-like protein HrpE PF06188.12 AII57702.1 - 1.6 8.6 11.2 2 8.3 11.2 1.1 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E XhlA PF10779.9 AII57702.1 - 1.8 8.9 7.1 1.9 8.8 1.5 2.4 2 0 0 2 2 2 0 Haemolysin XhlA HSCB_C PF07743.13 AII57702.1 - 1.8 9.1 15.3 0.098 13.2 5.0 2.4 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain DUF5446 PF17522.2 AII57702.1 - 4.7 7.4 9.7 0.64 10.2 2.2 2.5 1 1 0 2 2 2 0 Family of unknown function (DUF5446) CinA_KH PF18146.1 AII57702.1 - 6.9 6.9 10.5 7.3 6.8 0.6 2.6 3 0 0 3 3 3 0 Damage-inducible protein CinA KH domain OSCP PF00213.18 AII57703.1 - 3e-46 157.7 1.3 3.4e-46 157.5 1.3 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit PMT2_N PF17987.1 AII57703.1 - 0.17 12.1 0.4 1.2 9.4 0.4 2.2 1 1 0 1 1 1 0 Phosphoethanolamine N-methyltransferase 2 N-terminal ATP-synt_ab PF00006.25 AII57704.1 - 1.3e-72 243.9 0.0 1.9e-72 243.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 AII57704.1 - 1.7e-46 157.6 1.8 3.3e-46 156.7 1.8 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 AII57704.1 - 7.4e-18 64.8 0.7 2.2e-17 63.3 0.7 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 AII57704.1 - 5.7e-05 22.6 0.7 0.00015 21.2 0.1 1.9 2 0 0 2 2 2 1 KaiC ATP-synt PF00231.19 AII57705.1 - 5e-87 292.2 0.1 5.6e-87 292.0 0.1 1.0 1 0 0 1 1 1 1 ATP synthase MNE1 PF13762.6 AII57705.1 - 0.2 11.6 0.0 0.49 10.4 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial splicing apparatus component ATP-synt_ab PF00006.25 AII57706.1 - 5.2e-62 209.3 0.0 7.4e-62 208.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 AII57706.1 - 1.6e-18 67.0 0.1 3.3e-18 66.0 0.1 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain T3SS_ATPase_C PF18269.1 AII57706.1 - 0.011 15.6 0.7 0.083 12.8 0.7 2.2 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain NACHT PF05729.12 AII57706.1 - 0.025 14.5 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 AII57706.1 - 0.028 14.0 0.0 0.057 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 AII57706.1 - 0.076 12.2 0.2 0.29 10.3 0.1 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_16 PF13191.6 AII57706.1 - 0.096 13.1 0.1 0.47 10.8 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain ATP-synt_DE_N PF02823.16 AII57707.1 - 1.7e-29 101.5 0.1 2.6e-29 100.9 0.1 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ATP-synt_DE PF00401.20 AII57707.1 - 2.2e-10 40.6 9.8 4.3e-10 39.7 9.8 1.5 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, long alpha-helix domain RimM PF01782.18 AII57708.1 - 2e-13 50.4 0.0 2.8e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 RimM N-terminal domain PRC PF05239.16 AII57708.1 - 6.4e-10 39.0 0.6 6.4e-10 39.0 0.6 2.2 3 0 0 3 3 3 1 PRC-barrel domain KH_4 PF13083.6 AII57709.1 - 1.2e-22 79.5 1.2 1.3e-22 79.4 1.2 1.0 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 AII57709.1 - 0.001 18.9 1.3 0.0012 18.7 1.3 1.1 1 0 0 1 1 1 1 KH domain Ribosomal_S16 PF00886.19 AII57710.1 - 1.2e-20 73.4 0.1 1.4e-20 73.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 Endonuclease_5 PF04493.14 AII57711.1 - 2.3e-69 233.0 0.0 2.7e-69 232.8 0.0 1.0 1 0 0 1 1 1 1 Endonuclease V DUF99 PF01949.16 AII57711.1 - 0.00051 19.5 0.0 0.0007 19.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF99 PCRF PF03462.18 AII57712.1 - 8.1e-54 182.4 0.1 1.3e-53 181.8 0.1 1.3 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 AII57712.1 - 1.2e-39 134.9 2.3 4.5e-39 133.0 0.3 2.1 2 0 0 2 2 2 1 RF-1 domain ABC_tran_CTD PF16326.5 AII57712.1 - 0.011 15.9 6.4 0.098 12.9 0.9 2.8 3 1 0 3 3 3 0 ABC transporter C-terminal domain Thiamine_BP PF01910.17 AII57712.1 - 0.016 15.1 0.0 0.053 13.4 0.0 1.9 2 0 0 2 2 2 0 Thiamine-binding protein Peptidase_MA_2 PF13485.6 AII57713.1 - 1.2e-137 457.3 4.9 1.7e-137 456.8 4.9 1.2 1 0 0 1 1 1 1 Peptidase MA superfamily DUF1570 PF07607.11 AII57713.1 - 0.0015 18.8 0.2 0.081 13.2 0.0 2.3 1 1 0 2 2 2 1 Protein of unknown function (DUF1570) Peptidase_M1 PF01433.20 AII57713.1 - 0.0016 18.1 0.2 0.0074 15.9 0.2 1.9 1 1 0 1 1 1 1 Peptidase family M1 domain RadC PF04002.15 AII57714.1 - 4.9e-40 136.3 0.0 1e-39 135.3 0.0 1.5 1 0 0 1 1 1 1 RadC-like JAB domain HHH_5 PF14520.6 AII57714.1 - 0.00091 19.8 0.0 0.0024 18.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 AII57714.1 - 0.0017 18.1 0.0 0.005 16.7 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.7 AII57714.1 - 0.0025 17.9 0.0 0.0053 16.8 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif SBP_bac_5 PF00496.22 AII57715.1 - 5e-78 262.7 0.3 6e-78 262.4 0.3 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle LPAM_1 PF08139.12 AII57715.1 - 6.3 7.5 5.3 62 4.4 5.3 2.5 1 1 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site DUF4282 PF14110.6 AII57716.1 - 0.085 13.6 7.4 0.11 13.2 7.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) Aminotran_1_2 PF00155.21 AII57717.1 - 8.8e-40 137.0 0.0 1.1e-39 136.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 AII57717.1 - 0.0001 21.4 0.0 0.00016 20.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Alliinase_C PF04864.13 AII57717.1 - 0.00029 19.8 0.0 0.00034 19.6 0.0 1.2 1 0 0 1 1 1 1 Allinase Cys_Met_Meta_PP PF01053.20 AII57717.1 - 0.048 12.2 0.0 0.078 11.5 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF3861 PF12977.7 AII57717.1 - 0.15 12.2 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3861) tRNA-synt_2b PF00587.25 AII57718.1 - 2.6e-29 102.4 0.0 3.9e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 AII57718.1 - 1.1e-19 70.6 7.1 4.9e-19 68.5 7.1 2.0 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain SPAM PF02090.15 AII57718.1 - 0.13 12.1 4.1 0.23 11.2 4.1 1.3 1 0 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein SOGA PF11365.8 AII57718.1 - 0.8 10.9 4.9 28 5.9 4.7 2.9 1 1 0 1 1 1 0 Protein SOGA TSC22 PF01166.18 AII57718.1 - 2.1 8.8 4.0 14 6.0 0.2 2.6 1 1 1 2 2 2 0 TSC-22/dip/bun family JIP_LZII PF16471.5 AII57718.1 - 3.4 7.9 6.5 3.8 7.8 3.4 2.2 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II DUF4140 PF13600.6 AII57718.1 - 5.7 7.4 6.2 17 6.0 1.3 2.8 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) tRNA-synt_2 PF00152.20 AII57719.1 - 1.4e-82 277.3 0.0 1.7e-82 277.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 AII57719.1 - 5.6e-17 61.5 0.0 9.8e-17 60.7 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 AII57719.1 - 7.8e-05 22.3 0.1 0.24 10.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF4254 PF14063.6 AII57719.1 - 0.044 13.6 0.1 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4254) KRAP_IP3R_bind PF14722.6 AII57719.1 - 0.044 13.5 0.2 0.1 12.4 0.2 1.5 1 0 0 1 1 1 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain Adeno_E3_CR2 PF02439.15 AII57720.1 - 0.005 16.6 2.0 0.0057 16.4 2.0 1.1 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF515 PF04415.12 AII57720.1 - 0.013 14.0 0.1 0.013 13.9 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Syndecan PF01034.20 AII57720.1 - 0.032 14.1 0.1 0.032 14.1 0.1 1.2 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 AII57720.1 - 0.14 13.0 0.1 0.15 12.9 0.1 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CBP_BcsF PF11120.8 AII57720.1 - 0.17 12.0 0.4 0.21 11.8 0.4 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsF DUF4234 PF14018.6 AII57720.1 - 0.28 11.3 1.8 0.44 10.7 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) RecO_C PF02565.15 AII57721.1 - 4.8e-29 101.2 1.1 6.2e-29 100.8 1.1 1.2 1 0 0 1 1 1 1 Recombination protein O C terminal RecO_N PF11967.8 AII57721.1 - 9.7e-19 67.1 0.1 1.6e-18 66.5 0.1 1.4 1 0 0 1 1 1 1 Recombination protein O N terminal ArfGap PF01412.18 AII57721.1 - 0.038 14.0 0.2 0.064 13.3 0.2 1.3 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf FYVE_2 PF02318.16 AII57721.1 - 0.067 13.4 0.1 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger DUF3979 PF13141.6 AII57721.1 - 0.12 12.7 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3979) DNA_alkylation PF08713.11 AII57722.1 - 2.3e-33 115.7 2.7 3.3e-33 115.2 2.6 1.3 1 1 0 1 1 1 1 DNA alkylation repair enzyme Enterotoxin_ST PF02048.16 AII57722.1 - 0.08 13.4 0.6 0.17 12.4 0.6 1.5 1 0 0 1 1 1 0 Heat-stable enterotoxin ST CorA PF01544.18 AII57723.1 - 3.2e-74 249.9 0.5 3.9e-74 249.6 0.5 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein T2SSF PF00482.23 AII57723.1 - 0.014 15.4 0.0 0.014 15.4 0.0 1.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF2207 PF09972.9 AII57723.1 - 0.14 10.9 0.4 0.19 10.4 0.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Gram_pos_anchor PF00746.21 AII57723.1 - 1.1 9.2 3.2 0.95 9.5 1.3 1.8 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Toprim_4 PF13662.6 AII57724.1 - 2e-24 85.9 0.0 3.5e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 Toprim domain RecR PF02132.15 AII57724.1 - 4.9e-13 48.4 3.2 9.5e-13 47.5 3.2 1.5 1 0 0 1 1 1 1 RecR protein Toprim PF01751.22 AII57724.1 - 1.7e-08 34.6 0.0 3.4e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain HHH PF00633.23 AII57724.1 - 0.00048 19.9 0.1 0.0015 18.3 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif Prok-RING_4 PF14447.6 AII57724.1 - 0.0036 17.1 2.1 0.0058 16.5 2.1 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 HHH_5 PF14520.6 AII57724.1 - 0.013 16.1 0.0 0.042 14.5 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain IMS_HHH PF11798.8 AII57724.1 - 0.054 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 IMS family HHH motif YbaB_DNA_bd PF02575.16 AII57725.1 - 4.8e-21 74.8 6.4 5.6e-21 74.6 6.4 1.0 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family CSN5_C PF18323.1 AII57725.1 - 0.12 13.3 3.5 0.17 12.8 3.5 1.2 1 0 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain DNA_pol3_delta2 PF13177.6 AII57726.1 - 7.7e-47 159.1 0.0 1.6e-46 158.0 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 AII57726.1 - 5.2e-13 49.6 0.0 1.6e-12 48.0 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_gamma3 PF12169.8 AII57726.1 - 5e-12 45.9 0.5 1.3e-11 44.6 0.5 1.7 1 0 0 1 1 1 1 DNA polymerase III subunits gamma and tau domain III RuvB_N PF05496.12 AII57726.1 - 1.3e-07 31.5 0.1 6.5e-05 22.7 0.0 2.5 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 AII57726.1 - 1.4e-05 25.4 0.1 0.0001 22.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 AII57726.1 - 8.6e-05 22.3 0.0 0.00056 19.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 AII57726.1 - 0.00071 19.6 0.1 0.007 16.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 AII57726.1 - 0.00074 19.5 0.2 0.0026 17.7 0.0 2.0 2 0 0 2 2 1 1 Rad17 P-loop domain DNA_pol3_delta PF06144.13 AII57726.1 - 0.0011 18.7 1.1 0.0041 16.9 0.0 2.4 3 0 0 3 3 3 1 DNA polymerase III, delta subunit AAA_24 PF13479.6 AII57726.1 - 0.0011 18.7 0.0 0.0029 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AII57726.1 - 0.002 18.5 0.4 0.016 15.6 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain Glyco_tranf_2_5 PF13712.6 AII57726.1 - 0.0031 17.2 0.0 0.0073 16.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family DUF815 PF05673.13 AII57726.1 - 0.013 14.6 0.0 0.025 13.8 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF815) MinC_N PF05209.13 AII57726.1 - 0.02 14.8 0.6 7 6.7 0.0 3.8 3 1 1 4 4 4 0 Septum formation inhibitor MinC, N-terminal domain AAA_19 PF13245.6 AII57726.1 - 0.056 13.8 4.5 0.092 13.1 0.4 3.1 3 2 0 3 3 3 0 AAA domain AAA_18 PF13238.6 AII57726.1 - 0.056 14.0 0.5 0.18 12.3 0.2 2.2 2 1 0 2 2 1 0 AAA domain AAA_assoc_2 PF16193.5 AII57726.1 - 0.081 13.3 0.1 0.31 11.4 0.1 2.1 1 0 0 1 1 1 0 AAA C-terminal domain AAA_7 PF12775.7 AII57726.1 - 0.13 11.8 0.1 1.5 8.3 0.1 2.2 1 1 0 1 1 1 0 P-loop containing dynein motor region PCI PF01399.27 AII57726.1 - 0.16 12.5 1.6 2 9.0 0.1 2.9 2 1 1 3 3 3 0 PCI domain ResIII PF04851.15 AII57726.1 - 0.6 10.1 5.4 3.4 7.6 0.0 3.3 4 1 1 5 5 5 0 Type III restriction enzyme, res subunit SKI PF01202.22 AII57726.1 - 0.93 9.6 3.4 0.53 10.4 0.2 2.3 2 0 0 2 2 2 0 Shikimate kinase SLS PF14611.6 AII57726.1 - 0.96 9.2 7.5 0.32 10.8 2.8 2.5 2 1 1 3 3 2 0 Mitochondrial inner-membrane-bound regulator GatB_Yqey PF02637.18 AII57727.1 - 0.0004 20.3 0.4 0.047 13.6 0.1 2.1 2 0 0 2 2 2 2 GatB domain DUF2089 PF09862.9 AII57727.1 - 0.11 12.5 0.2 0.25 11.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) DUF2089 PF09862.9 AII57729.1 - 4.1e-31 107.4 0.0 4.7e-31 107.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2089) Sigma70_r4_2 PF08281.12 AII57729.1 - 0.0063 16.2 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_30 PF13556.6 AII57729.1 - 0.013 15.3 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain NUMOD1 PF07453.13 AII57729.1 - 0.029 14.6 0.0 0.047 14.0 0.0 1.3 1 0 0 1 1 1 0 NUMOD1 domain Exonuc_VII_S PF02609.16 AII57729.1 - 0.07 13.2 0.2 0.16 12.1 0.2 1.6 1 0 0 1 1 1 0 Exonuclease VII small subunit Tubulin PF00091.25 AII57730.1 - 7.4e-31 107.9 0.0 1.7e-30 106.7 0.0 1.6 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 AII57730.1 - 3.4e-07 29.8 0.0 0.00025 20.3 0.0 2.2 1 1 0 2 2 2 2 Tubulin like Gp_dh_C PF02800.20 AII57731.1 - 9e-68 226.8 0.3 1.6e-67 226.0 0.0 1.5 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 AII57731.1 - 5.3e-37 126.2 0.1 2e-36 124.3 0.0 2.0 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DUF1989 PF09347.10 AII57731.1 - 0.11 12.1 0.1 0.18 11.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1989) HGD-D PF06050.13 AII57732.1 - 1.1e-24 87.8 0.0 1.3e-24 87.6 0.0 1.0 1 0 0 1 1 1 1 2-hydroxyglutaryl-CoA dehydratase, D-component Enolase_C PF00113.22 AII57733.1 - 4.6e-131 436.4 0.1 5.9e-131 436.1 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 AII57733.1 - 6.8e-60 201.0 0.2 1.2e-59 200.2 0.2 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 AII57733.1 - 0.00019 21.1 0.0 0.00037 20.1 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 AII57733.1 - 0.00067 18.9 0.5 0.0014 17.8 0.5 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus LDcluster4 PF18306.1 AII57734.1 - 1.3e-41 141.8 4.1 1.6e-41 141.5 4.1 1.0 1 0 0 1 1 1 1 SLOG cluster4 family DNA_processg_A PF02481.15 AII57734.1 - 3.6e-09 36.2 2.1 1.7e-07 30.7 0.3 2.1 1 1 1 2 2 2 2 DNA recombination-mediator protein A Lysine_decarbox PF03641.14 AII57734.1 - 1.8e-07 31.3 0.0 2.7e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase Pept_tRNA_hydro PF01195.19 AII57735.1 - 1.1e-58 198.0 0.0 1.3e-58 197.8 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase DNA_ligase_aden PF01653.18 AII57736.1 - 1.1e-121 405.8 0.0 1.6e-121 405.3 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 AII57736.1 - 1e-30 105.4 1.0 1.8e-30 104.6 1.0 1.4 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain HHH_2 PF12826.7 AII57736.1 - 8.5e-26 89.8 0.1 8.9e-21 73.8 0.1 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_5 PF14520.6 AII57736.1 - 3.7e-14 53.1 1.3 1.5e-07 31.9 0.2 2.5 2 0 0 2 2 2 2 Helix-hairpin-helix domain BRCT PF00533.26 AII57736.1 - 8.4e-12 45.3 0.0 1.9e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_ZBD PF03119.16 AII57736.1 - 7.9e-08 32.2 5.5 1.6e-07 31.2 5.5 1.5 1 0 0 1 1 1 1 NAD-dependent DNA ligase C4 zinc finger domain HHH PF00633.23 AII57736.1 - 5.5e-05 22.8 0.2 0.019 14.8 0.1 2.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif PTCB-BRCT PF12738.7 AII57736.1 - 6.1e-05 22.9 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain RNA_pol_A_CTD PF03118.15 AII57736.1 - 0.00027 20.6 0.0 0.0039 16.9 0.0 2.7 3 0 0 3 3 3 1 Bacterial RNA polymerase, alpha chain C terminal domain HHH_3 PF12836.7 AII57736.1 - 0.0063 16.7 0.3 6.4 7.1 0.0 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 AII57736.1 - 0.022 15.4 0.2 0.28 11.8 0.0 2.8 2 1 1 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold HHH_8 PF14716.6 AII57736.1 - 0.055 13.8 3.3 6.7 7.2 0.0 4.6 6 0 0 6 6 5 0 Helix-hairpin-helix domain PP_kinase_C_1 PF17941.1 AII57736.1 - 0.15 11.6 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain 1 zf-RRN7 PF11781.8 AII57736.1 - 0.19 11.5 0.2 0.33 10.7 0.2 1.4 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DUF1015 PF06245.11 AII57737.1 - 2.6e-114 382.1 0.0 2.9e-114 382.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1015) SNO PF01174.19 AII57738.1 - 7.8e-65 218.2 0.0 8.8e-65 218.1 0.0 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 AII57738.1 - 1.1e-10 41.5 0.0 3e-10 40.0 0.0 1.7 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 AII57738.1 - 2.9e-07 30.5 0.0 6.6e-07 29.3 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_S51 PF03575.17 AII57738.1 - 1.3e-05 24.9 0.0 1.9e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 Peptidase_C26 PF07722.13 AII57738.1 - 0.00012 21.9 0.0 0.0016 18.2 0.0 2.5 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 AII57738.1 - 0.032 14.0 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family 2-Hacid_dh_C PF02826.19 AII57739.1 - 3.5e-63 212.2 0.1 9.7e-63 210.7 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 AII57739.1 - 6.4e-35 119.7 0.1 9.6e-35 119.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 AII57739.1 - 1.2e-05 25.6 0.1 6.2e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 AII57739.1 - 0.0049 17.4 0.4 0.023 15.3 0.0 2.3 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent ACT PF01842.25 AII57739.1 - 0.0075 16.0 0.0 0.031 14.1 0.0 2.1 2 0 0 2 2 2 1 ACT domain IlvN PF07991.12 AII57739.1 - 0.0078 15.8 0.0 0.019 14.5 0.0 1.7 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Aminotran_5 PF00266.19 AII57740.1 - 2.1e-48 165.1 0.0 2.8e-48 164.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AII57740.1 - 0.00041 19.0 0.1 0.00059 18.5 0.1 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GDC-P PF02347.16 AII57740.1 - 0.0053 15.6 0.3 0.097 11.5 0.0 2.1 2 0 0 2 2 2 1 Glycine cleavage system P-protein 2-Hacid_dh_C PF02826.19 AII57740.1 - 0.099 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain tRNA-synt_1b PF00579.25 AII57741.1 - 7.4e-73 245.4 0.1 9e-73 245.1 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 AII57741.1 - 2.4e-08 33.6 0.4 1e-07 31.6 0.0 2.3 3 0 0 3 3 3 1 S4 domain TyrRSs_C PF16714.5 AII57741.1 - 0.019 14.8 0.0 0.064 13.1 0.0 1.9 1 0 0 1 1 1 0 Tyrosyl-tRNA synthetase C-terminal domain tRNA-synt_1 PF00133.22 AII57741.1 - 0.081 11.2 0.0 0.13 10.5 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) FAD_syn PF06574.12 AII57742.1 - 1.2e-45 155.2 0.2 1.8e-45 154.7 0.2 1.2 1 0 0 1 1 1 1 FAD synthetase Flavokinase PF01687.17 AII57742.1 - 9.9e-35 119.2 0.0 1.7e-34 118.5 0.0 1.4 1 0 0 1 1 1 1 Riboflavin kinase CTP_transf_like PF01467.26 AII57742.1 - 3.6e-05 24.0 0.1 7.6e-05 22.9 0.1 1.6 1 1 0 1 1 1 1 Cytidylyltransferase-like RNA_pol_Rpb2_6 PF00562.28 AII57743.1 - 3e-169 563.2 0.0 3.1e-168 559.8 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_2 PF04561.14 AII57743.1 - 4.3e-33 114.5 0.0 1e-32 113.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 AII57743.1 - 7e-30 103.0 0.0 1.5e-29 102.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 AII57743.1 - 3.7e-26 91.4 0.0 7.9e-26 90.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_45 PF10385.9 AII57743.1 - 2.5e-21 75.7 0.3 2.2e-20 72.7 0.5 2.5 2 0 0 2 2 2 1 RNA polymerase beta subunit external 1 domain RNA_pol_Rpb2_1 PF04563.15 AII57743.1 - 1.2e-19 70.7 0.0 9.2e-19 67.8 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb1_1 PF04997.12 AII57744.1 - 1.1e-82 277.9 0.2 1.9e-82 277.1 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 AII57744.1 - 5.1e-67 226.1 2.9 7.5e-67 225.6 0.3 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 AII57744.1 - 5.4e-38 130.8 0.4 9.2e-27 94.3 0.0 3.4 3 1 1 4 4 4 2 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 AII57744.1 - 3.8e-25 88.7 0.1 1.1e-24 87.2 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 AII57744.1 - 1.3e-13 50.8 1.9 1.6e-13 50.5 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Peptidase_M23 PF01551.22 AII57744.1 - 5.1e-05 23.4 0.8 0.26 11.5 0.2 2.9 1 1 1 2 2 2 2 Peptidase family M23 Apocytochr_F_C PF01333.19 AII57744.1 - 0.0025 17.8 3.9 0.11 12.6 0.2 3.2 2 1 1 3 3 3 2 Apocytochrome F, C-terminal RuvB_N PF05496.12 AII57745.1 - 8.3e-81 269.4 0.0 1.5e-80 268.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_4 PF17864.1 AII57745.1 - 4.9e-30 103.1 0.4 8.9e-30 102.3 0.4 1.5 1 0 0 1 1 1 1 RuvB AAA lid domain RuvB_C PF05491.13 AII57745.1 - 3.2e-27 94.2 0.0 5.3e-27 93.5 0.0 1.4 1 0 0 1 1 1 1 RuvB C-terminal winged helix domain AAA PF00004.29 AII57745.1 - 3.5e-19 69.5 0.0 6.3e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AII57745.1 - 1.7e-08 34.5 0.1 1.7e-06 28.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 AII57745.1 - 5.7e-05 22.6 0.3 0.042 13.2 0.0 2.6 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 AII57745.1 - 0.0005 19.4 0.4 0.0029 16.9 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain Bac_DnaA PF00308.18 AII57745.1 - 0.00051 20.0 0.1 0.042 13.7 0.0 2.8 3 0 0 3 3 3 1 Bacterial dnaA protein TsaE PF02367.17 AII57745.1 - 0.0011 18.9 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 AII57745.1 - 0.0013 18.0 0.0 0.21 10.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 AII57745.1 - 0.003 17.3 0.0 0.0089 15.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AII57745.1 - 0.0036 17.7 0.2 0.045 14.1 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_3 PF07726.11 AII57745.1 - 0.0042 16.9 0.0 0.21 11.5 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AII57745.1 - 0.0047 17.2 0.0 1 9.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 AII57745.1 - 0.0068 16.1 0.0 3 7.5 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain NB-ARC PF00931.22 AII57745.1 - 0.008 15.4 0.0 0.46 9.6 0.0 2.4 3 0 0 3 3 3 1 NB-ARC domain IstB_IS21 PF01695.17 AII57745.1 - 0.017 14.9 0.1 0.094 12.4 0.1 2.0 1 1 0 1 1 1 0 IstB-like ATP binding protein Resolvase PF00239.21 AII57745.1 - 0.028 14.5 0.0 0.082 13.0 0.0 1.7 2 0 0 2 2 1 0 Resolvase, N terminal domain AAA_18 PF13238.6 AII57745.1 - 0.028 15.0 0.0 0.08 13.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain MCM PF00493.23 AII57745.1 - 0.064 12.3 0.0 3.9 6.5 0.0 2.2 1 1 0 1 1 1 0 MCM P-loop domain NTPase_1 PF03266.15 AII57745.1 - 0.074 13.0 0.2 0.45 10.4 0.0 2.1 1 1 1 2 2 2 0 NTPase RNA_helicase PF00910.22 AII57745.1 - 0.081 13.3 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA helicase ResIII PF04851.15 AII57745.1 - 0.15 12.1 0.0 3.7 7.5 0.0 2.1 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Rad17 PF03215.15 AII57745.1 - 0.18 11.7 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain QueH PF02677.14 AII57746.1 - 1.1e-50 172.1 5.2 1.2e-50 172.0 5.2 1.0 1 0 0 1 1 1 1 Epoxyqueuosine reductase QueH Acetyltransf_1 PF00583.25 AII57747.1 - 7.7e-11 42.3 0.1 1e-10 41.8 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AII57747.1 - 6.6e-09 35.8 0.3 3.7e-08 33.4 0.1 1.9 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AII57747.1 - 7.5e-09 35.9 0.0 9.9e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AII57747.1 - 2.4e-06 27.4 0.1 5e-06 26.4 0.1 1.6 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.7 AII57747.1 - 0.00062 19.8 0.0 0.73 9.9 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain PanZ PF12568.8 AII57747.1 - 0.041 13.6 0.0 0.096 12.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ AstA PF04958.12 AII57747.1 - 0.11 11.0 0.0 2.2 6.7 0.0 2.1 2 0 0 2 2 2 0 Arginine N-succinyltransferase beta subunit Prim_Zn_Ribbon PF08273.12 AII57748.1 - 0.0057 16.9 0.4 0.0079 16.4 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding domain of primase-helicase Zn_Tnp_IS1595 PF12760.7 AII57748.1 - 0.011 15.7 0.6 0.018 15.0 0.6 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zinc_ribbon_5 PF13719.6 AII57748.1 - 0.013 15.2 0.9 0.034 13.9 0.9 1.7 1 1 0 1 1 1 0 zinc-ribbon domain zf-H2C2_2 PF13465.6 AII57748.1 - 0.056 13.9 5.2 0.082 13.4 1.3 2.2 2 0 0 2 2 2 0 Zinc-finger double domain Zn-ribbon_8 PF09723.10 AII57748.1 - 0.37 10.9 3.1 18 5.5 0.4 2.7 2 1 0 2 2 2 0 Zinc ribbon domain zf-C2H2 PF00096.26 AII57748.1 - 0.58 10.7 2.5 27 5.5 0.7 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type ArsP_1 PF03773.13 AII57749.1 - 1.4e-16 60.6 7.2 1.4e-16 60.6 7.2 1.4 2 0 0 2 2 2 1 Predicted permease DUF3488 PF11992.8 AII57749.1 - 3.9 6.4 8.2 0.073 12.0 0.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3488) Methyltransf_25 PF13649.6 AII57750.1 - 7.7e-19 68.2 0.0 1.6e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AII57750.1 - 6.3e-18 65.2 0.0 9.7e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AII57750.1 - 2.1e-13 50.4 0.0 2.8e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AII57750.1 - 4.2e-13 49.4 0.0 5.5e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AII57750.1 - 2.6e-11 44.1 0.0 3.9e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AII57750.1 - 2.5e-07 30.3 0.0 6e-07 29.0 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 AII57750.1 - 0.026 14.1 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 AII57750.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Radical_SAM_C PF16199.5 AII57751.1 - 1.9e-21 75.9 0.0 4.1e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 AII57751.1 - 7.5e-19 68.7 0.1 1.5e-18 67.8 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 AII57751.1 - 1.2e-05 25.6 0.1 2.1e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AII57751.1 - 4.2e-05 23.5 0.1 7.2e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AII57751.1 - 0.012 16.0 0.2 0.025 15.0 0.2 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 AII57751.1 - 0.046 13.7 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Oxidored_q6 PF01058.22 AII57752.1 - 3.2e-32 111.1 0.1 5.3e-32 110.4 0.1 1.4 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit NiFe_hyd_SSU_C PF14720.6 AII57752.1 - 0.0069 16.7 0.6 0.014 15.7 0.6 1.5 1 0 0 1 1 1 1 NiFe/NiFeSe hydrogenase small subunit C-terminal NiFeSe_Hases PF00374.19 AII57753.1 - 2.5e-33 115.8 0.0 3.8e-18 65.7 0.0 3.1 3 0 0 3 3 3 3 Nickel-dependent hydrogenase SL4P PF17618.2 AII57753.1 - 0.12 12.4 0.8 1.7 8.7 0.1 2.7 3 0 0 3 3 3 0 Uncharacterized Strongylid L4 protein RRF PF01765.19 AII57753.1 - 0.14 12.1 0.4 4.8 7.1 0.1 2.3 2 0 0 2 2 2 0 Ribosome recycling factor HycI PF01750.18 AII57754.1 - 7.7e-18 64.6 0.8 9e-18 64.3 0.8 1.1 1 0 0 1 1 1 1 Hydrogenase maturation protease CPSase_L_D2 PF02786.17 AII57755.1 - 0.038 13.5 0.0 0.056 12.9 0.0 1.2 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain AhpC-TSA PF00578.21 AII57756.1 - 2e-25 89.1 0.0 2.4e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 AII57756.1 - 1.6e-18 66.8 0.0 2.2e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 AII57756.1 - 1.2e-06 28.8 0.0 1.8e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 AII57756.1 - 0.00017 21.5 0.1 0.00041 20.3 0.1 1.6 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 AII57756.1 - 0.0017 18.8 0.0 0.0024 18.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain zf-C2H2_10 PF16588.5 AII57756.1 - 0.36 10.6 3.3 0.69 9.7 3.3 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger DsbD PF02683.15 AII57757.1 - 5.5e-46 157.1 16.1 6.5e-46 156.9 16.1 1.0 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.6 AII57757.1 - 4.5e-09 36.5 17.1 6.1e-09 36.1 17.1 1.2 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region PDDEXK_1 PF12705.7 AII57758.1 - 3.7e-33 115.5 0.6 5.9e-33 114.8 0.6 1.3 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Csa1 PF06023.12 AII57758.1 - 0.00021 20.7 0.0 0.00031 20.2 0.0 1.3 1 0 0 1 1 1 1 CRISPR-associated exonuclease Csa1 Sm_multidrug_ex PF06695.11 AII57759.1 - 6.8e-10 39.6 3.5 1.1e-09 38.9 3.5 1.3 1 0 0 1 1 1 1 Putative small multi-drug export protein ATP1G1_PLM_MAT8 PF02038.16 AII57759.1 - 0.0043 16.5 0.3 0.013 14.9 0.3 1.8 1 0 0 1 1 1 1 ATP1G1/PLM/MAT8 family Radical_SAM PF04055.21 AII57760.1 - 6.3e-13 49.4 0.1 3.4e-12 47.0 0.0 1.9 1 1 1 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 AII57760.1 - 5.4e-07 30.0 0.0 9.2e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AII57760.1 - 0.00023 21.3 0.0 0.0014 18.7 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S single cluster domain Ribonuc_red_lgC PF02867.15 AII57761.1 - 1.3e-139 466.1 0.0 4.7e-100 335.6 0.0 2.2 1 1 1 2 2 2 2 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 AII57761.1 - 4.8e-26 90.6 0.0 1.1e-25 89.4 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain Response_reg PF00072.24 AII57762.1 - 2.1e-26 92.3 0.5 3.7e-26 91.5 0.5 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HD PF01966.22 AII57762.1 - 1.2e-21 77.2 0.4 2.2e-21 76.3 0.4 1.4 1 0 0 1 1 1 1 HD domain HD_5 PF13487.6 AII57762.1 - 1.2e-19 70.3 0.5 2.8e-19 69.1 0.5 1.6 1 0 0 1 1 1 1 HD domain HDOD PF08668.12 AII57762.1 - 7.1e-06 25.6 0.0 1.3e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 HDOD domain PAS_9 PF13426.7 AII57763.1 - 3.4e-40 136.5 6.6 1.8e-09 37.8 0.3 5.1 5 0 0 5 5 5 4 PAS domain PAS_4 PF08448.10 AII57763.1 - 1.5e-23 83.1 0.0 1.3e-07 31.8 0.0 4.8 5 0 0 5 5 5 4 PAS fold HATPase_c PF02518.26 AII57763.1 - 1.3e-19 70.8 0.7 3.3e-19 69.5 0.2 2.0 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 AII57763.1 - 1.7e-18 66.6 0.0 2.4e-05 24.5 0.0 6.0 5 1 0 5 5 5 4 PAS fold PAS PF00989.25 AII57763.1 - 2.2e-18 66.3 0.8 3.5e-05 23.8 0.1 5.4 5 0 0 5 5 5 3 PAS fold HisKA PF00512.25 AII57763.1 - 1.6e-17 63.2 1.9 2e-17 62.9 0.5 2.0 2 0 0 2 2 1 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 AII57763.1 - 2e-17 62.7 0.0 0.00031 20.7 0.0 4.8 4 0 0 4 4 4 4 PAS domain PAS_12 PF18095.1 AII57763.1 - 0.00034 20.3 6.3 1.1 8.8 0.0 4.8 4 1 1 5 5 5 2 UPF0242 C-terminal PAS-like domain HATPase_c_3 PF13589.6 AII57763.1 - 0.0046 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SRCR_2 PF15494.6 AII57763.1 - 0.016 15.8 0.1 2 9.0 0.0 2.8 2 0 0 2 2 2 0 Scavenger receptor cysteine-rich domain HATPase_c_2 PF13581.6 AII57763.1 - 0.18 11.8 0.0 1.4 8.9 0.0 2.4 3 0 0 3 3 3 0 Histidine kinase-like ATPase domain Imm30 PF15565.6 AII57763.1 - 0.22 11.6 1.7 1.8 8.7 0.1 3.0 2 1 0 2 2 2 0 Immunity protein 30 LZ3wCH PF18517.1 AII57763.1 - 0.27 11.3 1.2 5 7.3 0.1 3.4 3 0 0 3 3 3 0 Leucine zipper with capping helix domain CxxCxxCC PF03692.15 AII57764.1 - 1.3e-10 41.9 3.7 1.6e-10 41.5 3.7 1.1 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain TIG PF01833.24 AII57765.1 - 9.6e-10 38.4 3.5 0.011 15.8 0.4 3.3 3 0 0 3 3 3 3 IPT/TIG domain Big_6 PF17936.1 AII57765.1 - 0.00011 22.4 1.2 0.76 10.1 0.0 4.1 4 0 0 4 4 4 1 Bacterial Ig domain Big_7 PF17957.1 AII57765.1 - 0.0046 17.7 1.3 3.2 8.6 0.4 3.3 4 0 0 4 4 4 2 Bacterial Ig domain Neocarzinostat PF00960.18 AII57765.1 - 0.049 13.6 2.7 9.2 6.3 0.2 3.9 2 2 0 2 2 2 0 Neocarzinostatin family DUF4328 PF14219.6 AII57765.1 - 0.1 12.2 1.2 0.2 11.2 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) LAM_C PF12544.8 AII57766.1 - 2.4e-20 73.0 0.2 4.7e-20 72.0 0.2 1.5 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Radical_SAM PF04055.21 AII57766.1 - 5e-10 40.0 0.0 1.4e-09 38.5 0.0 1.8 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 AII57766.1 - 3.2e-07 30.5 0.0 1.4e-06 28.4 0.0 2.0 1 1 1 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 AII57766.1 - 3.8e-05 24.0 0.0 6.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Dala_Dala_lig_C PF07478.13 AII57767.1 - 5.5e-37 127.3 0.0 7.1e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus GARS_A PF01071.19 AII57767.1 - 4e-07 30.0 0.0 6.3e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.17 AII57767.1 - 2.5e-06 27.1 0.0 8.8e-06 25.4 0.0 1.8 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 AII57767.1 - 1.9e-05 24.3 0.0 8.8e-05 22.1 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 AII57767.1 - 3.6e-05 23.9 0.0 0.00016 21.7 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 AII57767.1 - 0.00095 18.8 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 AII57767.1 - 0.0057 16.3 0.0 0.07 12.7 0.0 2.0 2 0 0 2 2 2 1 RimK-like ATP-grasp domain TTL PF03133.15 AII57767.1 - 0.044 12.9 0.0 0.11 11.6 0.0 1.6 2 0 0 2 2 2 0 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 AII57767.1 - 0.093 12.0 0.0 8.9 5.5 0.0 2.3 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp ATPgrasp_Ter PF15632.6 AII57767.1 - 0.097 12.4 0.0 5.2 6.8 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon FUR PF01475.19 AII57768.1 - 8.8e-31 106.5 0.1 1e-30 106.3 0.1 1.1 1 0 0 1 1 1 1 Ferric uptake regulator family HTH_IclR PF09339.10 AII57768.1 - 0.0021 17.8 1.0 0.042 13.7 0.3 2.9 3 1 0 3 3 3 1 IclR helix-turn-helix domain HTH_20 PF12840.7 AII57768.1 - 0.0033 17.5 0.0 0.0053 16.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain TBPIP PF07106.13 AII57768.1 - 0.017 15.1 0.0 0.053 13.5 0.0 1.8 2 0 0 2 2 2 0 TBPIP/Hop2 winged helix domain HTH_12 PF08461.10 AII57768.1 - 0.06 13.3 0.0 0.31 11.0 0.0 2.1 2 1 0 2 2 2 0 Ribonuclease R winged-helix domain PHD PF00628.29 AII57768.1 - 0.53 10.2 5.7 1.7 8.6 5.8 1.8 1 1 0 1 1 1 0 PHD-finger ZnuA PF01297.17 AII57769.1 - 3.5e-61 206.8 0.0 4e-61 206.7 0.0 1.0 1 0 0 1 1 1 1 Zinc-uptake complex component A periplasmic ABC_tran PF00005.27 AII57770.1 - 1.1e-31 110.2 0.0 1.6e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AII57770.1 - 4.7e-13 49.6 0.0 1.1e-05 25.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AII57770.1 - 4e-06 26.4 0.0 1e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AII57770.1 - 0.0015 19.1 0.5 0.0026 18.3 0.5 1.3 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 AII57770.1 - 0.0043 16.8 0.0 0.15 11.8 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.6 AII57770.1 - 0.011 15.9 0.1 0.22 11.8 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 AII57770.1 - 0.028 14.8 0.0 0.044 14.2 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 AII57770.1 - 0.03 14.7 1.0 0.4 11.1 1.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AII57770.1 - 0.047 13.4 0.0 0.44 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 AII57770.1 - 0.065 13.0 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 AII57770.1 - 0.069 13.4 0.4 0.63 10.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 AII57770.1 - 0.089 12.7 0.7 0.87 9.5 0.3 2.1 2 0 0 2 2 2 0 NACHT domain Fer4_23 PF18009.1 AII57770.1 - 0.19 12.2 0.0 0.37 11.3 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron-sulfur cluster binding domain ABC-3 PF00950.17 AII57771.1 - 3.7e-80 269.1 29.9 4.2e-80 269.0 29.9 1.0 1 0 0 1 1 1 1 ABC 3 transport family FecCD PF01032.18 AII57771.1 - 3.7e-06 26.2 30.6 3.7e-06 26.2 30.6 1.5 1 1 0 1 1 1 1 FecCD transport family DUF4112 PF13430.6 AII57771.1 - 0.033 14.5 1.4 0.033 14.5 1.4 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4112) Tubulin PF00091.25 AII57773.1 - 3.8e-41 141.5 3.1 3.8e-41 141.5 3.1 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 AII57773.1 - 3.6e-30 104.1 0.4 3.6e-30 104.1 0.4 2.1 2 0 0 2 2 2 1 FtsZ family, C-terminal domain Tubulin_2 PF13809.6 AII57773.1 - 1.3 8.1 10.4 4.9 6.2 0.1 2.8 2 1 1 3 3 3 0 Tubulin like FtsA PF14450.6 AII57774.1 - 1.5e-29 102.4 0.3 2.1e-17 63.4 0.0 2.3 2 0 0 2 2 2 2 Cell division protein FtsA SHS2_FTSA PF02491.20 AII57774.1 - 3.4e-28 97.9 1.1 6.3e-28 97.0 1.1 1.5 1 0 0 1 1 1 1 SHS2 domain inserted in FTSA PilM_2 PF11104.8 AII57774.1 - 1.8e-11 43.7 0.2 3.6e-05 23.0 0.0 3.0 3 0 0 3 3 3 3 Type IV pilus assembly protein PilM; MreB_Mbl PF06723.13 AII57774.1 - 1.7e-10 40.2 4.8 1.3e-08 34.0 1.1 3.0 2 1 0 2 2 2 2 MreB/Mbl protein DDR PF08841.10 AII57774.1 - 1.5e-05 24.2 0.4 2.5e-05 23.4 0.4 1.3 1 0 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain EutA PF06277.11 AII57774.1 - 4.9e-05 22.4 0.0 9.5e-05 21.4 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutA Hydantoinase_A PF01968.18 AII57774.1 - 0.0011 18.3 0.1 0.0018 17.6 0.1 1.3 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase MutL PF13941.6 AII57774.1 - 0.027 13.1 0.2 0.059 12.0 0.0 1.6 2 0 0 2 2 2 0 MutL protein DUF3748 PF12566.8 AII57774.1 - 0.027 14.4 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3748) DUF5343 PF17278.2 AII57776.1 - 1.8e-11 44.3 0.0 2.5e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5343) Usp PF00582.26 AII57777.1 - 2.5e-35 122.0 0.0 7e-16 59.0 0.0 3.0 2 1 0 2 2 2 2 Universal stress protein family Elongin_A PF06881.11 AII57777.1 - 0.12 12.9 0.1 0.45 11.1 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Cyclase PF04199.13 AII57778.1 - 1.7e-18 67.2 0.0 2.2e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Putative cyclase Ribul_P_3_epim PF00834.19 AII57779.1 - 2.2e-46 157.8 0.0 2.5e-46 157.6 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family LacAB_rpiB PF02502.18 AII57780.1 - 1.1e-49 168.1 0.1 1.2e-49 167.9 0.1 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.6 AII57780.1 - 0.045 13.8 0.3 0.069 13.2 0.3 1.3 1 0 0 1 1 1 0 Glycine-rich SFCGS Transketolase_N PF00456.21 AII57781.1 - 6.6e-149 495.4 0.0 8.9e-149 495.0 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 AII57781.1 - 2.9e-46 157.4 0.0 5.2e-46 156.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 AII57781.1 - 6.9e-09 35.6 0.0 3.9e-08 33.2 0.0 2.2 1 1 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 AII57781.1 - 4.6e-06 26.0 0.0 0.023 13.9 0.0 2.8 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase Alba PF01918.21 AII57781.1 - 0.0097 15.7 0.1 0.03 14.2 0.0 1.8 2 0 0 2 2 2 1 Alba Nitroreductase PF00881.24 AII57782.1 - 8.7e-30 104.0 0.4 7.2e-14 52.2 0.0 2.0 1 1 1 2 2 2 2 Nitroreductase family TM1586_NiRdase PF14512.6 AII57782.1 - 1.5e-14 54.1 0.1 0.00014 21.6 0.0 3.1 1 1 2 3 3 3 3 Putative TM nitroreductase Methyltransf_25 PF13649.6 AII57783.1 - 2.2e-15 57.1 0.0 4.1e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AII57783.1 - 1.5e-11 44.4 0.0 3.3e-11 43.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AII57783.1 - 2.9e-11 43.4 0.0 3.9e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AII57783.1 - 5.4e-10 39.8 0.0 8.9e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AII57783.1 - 1.4e-09 38.6 0.0 2.3e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AII57783.1 - 3.6e-07 29.9 0.0 5.8e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 AII57783.1 - 0.00021 21.0 0.0 0.0003 20.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) TPMT PF05724.11 AII57783.1 - 0.00036 20.3 0.0 0.00066 19.4 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) TehB PF03848.14 AII57783.1 - 0.00068 19.1 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB CMAS PF02353.20 AII57783.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 AII57783.1 - 0.02 13.9 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 AII57783.1 - 0.03 14.3 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 AII57783.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase GidB PF02527.15 AII57783.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G LDcluster4 PF18306.1 AII57784.1 - 5.7e-46 156.0 1.2 6.5e-46 155.8 1.2 1.0 1 0 0 1 1 1 1 SLOG cluster4 family LSDAT_prok PF18171.1 AII57784.1 - 0.0003 20.1 0.0 0.001 18.3 0.0 1.8 2 0 0 2 2 2 1 SLOG in TRPM, prokaryote LD_cluster2 PF18163.1 AII57784.1 - 0.035 13.6 0.1 0.067 12.7 0.0 1.5 2 0 0 2 2 2 0 SLOG cluster2 AIRC PF00731.20 AII57784.1 - 0.17 11.4 0.0 0.38 10.3 0.0 1.5 1 0 0 1 1 1 0 AIR carboxylase Peripla_BP_2 PF01497.18 AII57785.1 - 6.7e-38 130.6 0.1 8.9e-38 130.2 0.1 1.2 1 0 0 1 1 1 1 Periplasmic binding protein WASH_WAHD PF11945.8 AII57785.1 - 0.022 14.3 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 WAHD domain of WASH complex DUF3837 PF12939.7 AII57785.1 - 0.061 13.7 0.2 0.44 11.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3837) DUF2884 PF11101.8 AII57785.1 - 0.066 12.7 0.2 0.11 12.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) RE_HindVP PF09519.10 AII57785.1 - 0.18 10.8 0.2 0.28 10.2 0.2 1.2 1 0 0 1 1 1 0 HindVP restriction endonuclease FecCD PF01032.18 AII57786.1 - 3.6e-101 338.3 41.0 4.2e-101 338.0 41.0 1.0 1 0 0 1 1 1 1 FecCD transport family ABC-3 PF00950.17 AII57786.1 - 1.4e-07 31.3 26.0 1.4e-07 31.3 26.0 1.6 2 0 0 2 2 2 1 ABC 3 transport family ABC_tran PF00005.27 AII57787.1 - 4.4e-30 105.0 0.0 6.1e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AII57787.1 - 5.8e-12 46.0 0.5 9.7e-05 22.3 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AII57787.1 - 3.4e-06 26.7 0.0 0.012 15.1 0.1 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 AII57787.1 - 6.8e-05 23.3 0.0 9.9e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AII57787.1 - 7.7e-05 22.4 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 AII57787.1 - 0.0034 17.5 0.1 0.034 14.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 AII57787.1 - 0.0057 17.2 0.0 0.011 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AII57787.1 - 0.0067 17.0 0.1 0.021 15.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 AII57787.1 - 0.012 15.6 0.0 0.055 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 AII57787.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_22 PF13401.6 AII57787.1 - 0.017 15.4 0.2 0.092 13.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 AII57787.1 - 0.021 15.2 0.0 0.037 14.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 AII57787.1 - 0.024 14.5 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Spore_IV_A PF09547.10 AII57787.1 - 0.025 13.6 0.0 0.033 13.1 0.0 1.1 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) AAA_30 PF13604.6 AII57787.1 - 0.025 14.3 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 AII57787.1 - 0.031 14.7 0.0 0.06 13.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 AII57787.1 - 0.045 13.8 0.5 0.11 12.6 0.1 1.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase MeaB PF03308.16 AII57787.1 - 0.053 12.5 0.1 0.09 11.7 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Thymidylate_kin PF02223.17 AII57787.1 - 0.058 13.1 0.0 3.1 7.4 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase AAA_15 PF13175.6 AII57787.1 - 0.06 13.1 0.0 0.082 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 AII57787.1 - 0.065 13.3 0.0 0.27 11.3 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_PrkA PF08298.11 AII57787.1 - 0.077 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain ABC_ATPase PF09818.9 AII57787.1 - 0.08 11.7 0.1 8.3 5.1 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class NACHT PF05729.12 AII57787.1 - 0.088 12.7 0.1 0.21 11.5 0.0 1.6 2 0 0 2 2 2 0 NACHT domain SRP54 PF00448.22 AII57787.1 - 0.089 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 AII57787.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 AII57787.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ATPase_2 PF01637.18 AII57787.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 AII57787.1 - 0.15 12.3 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 AII57787.1 - 0.16 11.6 0.1 0.4 10.3 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 AII57787.1 - 0.2 10.8 0.0 0.37 9.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_13 PF13166.6 AII57787.1 - 0.27 9.8 0.1 6.5 5.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain CbiZ PF01955.18 AII57788.1 - 6.7e-52 176.4 0.0 7.8e-52 176.2 0.0 1.0 1 0 0 1 1 1 1 Adenosylcobinamide amidohydrolase CobD_Cbib PF03186.13 AII57789.1 - 1.3e-88 296.8 0.4 1.6e-88 296.5 0.4 1.1 1 0 0 1 1 1 1 CobD/Cbib protein Aminotran_1_2 PF00155.21 AII57790.1 - 8.3e-54 183.1 0.0 9.9e-54 182.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II mTERF PF02536.14 AII57790.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 mTERF XFP_N PF09364.10 AII57790.1 - 0.22 10.3 0.0 0.5 9.1 0.0 1.5 1 1 0 1 1 1 0 XFP N-terminal domain DBI_PRT PF02277.17 AII57791.1 - 7e-130 433.1 15.3 7.9e-130 432.9 15.3 1.0 1 0 0 1 1 1 1 Phosphoribosyltransferase CobS PF02654.15 AII57792.1 - 8e-51 173.1 15.3 9.2e-51 172.9 15.3 1.0 1 0 0 1 1 1 1 Cobalamin-5-phosphate synthase His_Phos_1 PF00300.22 AII57793.1 - 1.6e-59 200.8 0.0 1.8e-59 200.7 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CobU PF02283.16 AII57794.1 - 7.1e-54 181.9 0.0 8e-54 181.7 0.0 1.0 1 0 0 1 1 1 1 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_18 PF13238.6 AII57794.1 - 0.0019 18.8 0.0 0.0027 18.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 AII57794.1 - 0.006 16.3 0.0 0.0081 15.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AII57794.1 - 0.0062 16.9 0.0 0.0082 16.5 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 AII57794.1 - 0.047 13.9 0.0 0.067 13.4 0.0 1.3 1 1 0 1 1 1 0 AAA domain Thioredoxin PF00085.20 AII57795.1 - 4.6e-35 119.7 0.1 5.1e-35 119.6 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 AII57795.1 - 1.9e-10 41.1 0.1 2.2e-09 37.7 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 AII57795.1 - 1.7e-08 34.7 0.0 4.2e-06 27.0 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.6 AII57795.1 - 3.6e-06 26.8 0.0 4e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 AII57795.1 - 1.1e-05 25.5 0.1 2.1e-05 24.6 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 AII57795.1 - 5e-05 23.0 0.1 5.5e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 Redoxin OST3_OST6 PF04756.13 AII57795.1 - 0.00042 19.8 0.0 0.00042 19.8 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 AII57795.1 - 0.0027 17.7 0.0 0.0045 17.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_5 PF13743.6 AII57795.1 - 0.0031 17.2 0.2 0.33 10.6 0.1 2.1 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.6 AII57795.1 - 0.017 15.0 0.0 0.024 14.6 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain TraF PF13728.6 AII57795.1 - 0.019 14.8 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein HyaE PF07449.11 AII57795.1 - 0.023 14.7 0.0 0.032 14.2 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.24 AII57795.1 - 0.032 14.5 0.1 0.053 13.7 0.1 1.4 1 1 0 1 1 1 0 Glutaredoxin HisKA_3 PF07730.13 AII57796.1 - 2e-13 50.7 5.6 6.3e-13 49.0 2.1 2.4 2 0 0 2 2 2 1 Histidine kinase HATPase_c PF02518.26 AII57796.1 - 6.9e-06 26.5 0.1 5e-05 23.8 0.0 2.3 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4118 PF13493.6 AII57796.1 - 0.011 15.5 0.4 0.025 14.4 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4118) SLATT_6 PF18169.1 AII57796.1 - 0.012 15.2 0.2 0.021 14.5 0.2 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 Response_reg PF00072.24 AII57797.1 - 6.4e-30 103.6 1.6 6.9e-30 103.5 0.6 1.6 2 0 0 2 2 2 1 Response regulator receiver domain GerE PF00196.19 AII57797.1 - 2.3e-21 75.1 0.1 5.8e-21 73.8 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_10 PF04967.12 AII57797.1 - 5.6e-05 22.9 0.2 0.00086 19.1 0.2 2.4 1 1 0 1 1 1 1 HTH DNA binding domain Sigma70_r4_2 PF08281.12 AII57797.1 - 8.2e-05 22.2 0.0 0.00018 21.1 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_40 PF14493.6 AII57797.1 - 0.0028 18.1 0.1 0.018 15.5 0.0 2.2 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_11 PF08279.12 AII57797.1 - 0.0045 16.9 0.1 0.012 15.5 0.1 1.9 1 0 0 1 1 1 1 HTH domain HTH_24 PF13412.6 AII57797.1 - 0.0052 16.3 0.1 0.029 13.9 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 AII57797.1 - 0.0066 16.2 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_ECF PF07638.11 AII57797.1 - 0.01 15.7 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 ECF sigma factor HTH_38 PF13936.6 AII57797.1 - 0.032 14.0 0.5 0.15 11.9 0.1 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 AII57797.1 - 0.085 12.4 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 CdhD PF03599.16 AII57798.1 - 2.2e-89 299.9 0.0 2.6e-89 299.6 0.0 1.0 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit FeS PF04060.13 AII57798.1 - 9.2e-13 47.6 2.9 2e-12 46.5 2.9 1.6 1 0 0 1 1 1 1 Putative Fe-S cluster CdhC PF03598.15 AII57799.1 - 4.7e-67 224.7 0.0 1e-66 223.6 0.0 1.6 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase complex beta subunit CODH_A_N PF18537.1 AII57799.1 - 1.8e-24 85.5 0.1 4e-24 84.4 0.1 1.6 1 0 0 1 1 1 1 Carbon monoxide dehydrogenase subunit alpha N-terminal domain CdhD PF03599.16 AII57800.1 - 9.8e-50 169.4 0.0 1.2e-49 169.1 0.0 1.0 1 0 0 1 1 1 1 CO dehydrogenase/acetyl-CoA synthase delta subunit DUF2064 PF09837.9 AII57800.1 - 0.19 11.5 0.0 0.41 10.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) THF_DHG_CYH_C PF02882.19 AII57801.1 - 1.1e-67 226.3 1.6 1.9e-67 225.6 1.6 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 AII57801.1 - 1.6e-38 131.5 0.1 2.4e-38 131.0 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain CbiA PF01656.23 AII57802.1 - 1.8e-10 41.0 0.1 2.7e-10 40.4 0.1 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AII57802.1 - 5.3e-09 36.2 0.1 1.4e-08 34.9 0.1 1.6 1 1 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 AII57802.1 - 1.6e-05 24.5 0.4 0.00012 21.7 0.4 2.1 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ArsA_ATPase PF02374.15 AII57802.1 - 9.8e-05 21.7 0.7 0.00013 21.2 0.1 1.6 2 1 0 2 2 2 1 Anion-transporting ATPase ParA PF10609.9 AII57802.1 - 0.01 15.3 3.0 0.086 12.3 3.0 2.4 1 1 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RsgA_GTPase PF03193.16 AII57802.1 - 0.027 14.4 0.4 5 7.0 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase Fer4_NifH PF00142.18 AII57802.1 - 0.033 13.7 0.1 4 6.8 0.0 2.1 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family KAP_NTPase PF07693.14 AII57802.1 - 0.07 12.4 0.0 0.14 11.4 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain AAA_24 PF13479.6 AII57802.1 - 0.084 12.6 0.0 1.1 8.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain RACo_C_ter PF14574.6 AII57803.1 - 2.5e-92 308.6 1.3 4.3e-92 307.8 1.3 1.4 1 0 0 1 1 1 1 C-terminal domain of RACo the ASKHA domain Raco_middle PF17651.1 AII57803.1 - 1.8e-51 174.1 0.0 3.6e-51 173.1 0.0 1.5 1 0 0 1 1 1 1 RACo middle region RACo_linker PF17650.1 AII57803.1 - 4.8e-16 58.4 0.0 9.6e-16 57.4 0.0 1.4 1 0 0 1 1 1 1 RACo linker region Fer2 PF00111.27 AII57803.1 - 1.8e-08 34.2 2.8 4.2e-08 33.0 2.8 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FTHFS PF01268.19 AII57804.1 - 8.1e-225 747.2 0.0 9.2e-225 747.0 0.0 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase BRCT_2 PF16589.5 AII57806.1 - 0.0095 16.3 0.0 0.012 16.0 0.0 1.2 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain tRNA-synt_2 PF00152.20 AII57807.1 - 1.3e-105 353.0 0.0 1.5e-105 352.7 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 AII57807.1 - 4e-17 61.9 0.1 8.3e-17 61.0 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain GAD PF02938.14 AII57807.1 - 4.1e-16 59.0 0.3 7.7e-16 58.1 0.3 1.5 1 0 0 1 1 1 1 GAD domain tRNA-synt_2d PF01409.20 AII57807.1 - 0.0043 16.6 0.2 0.029 13.9 0.1 2.1 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) NifQ PF04891.12 AII57807.1 - 0.0083 16.5 0.1 0.4 11.0 0.0 2.4 2 0 0 2 2 2 1 NifQ tRNA-synt_2b PF00587.25 AII57807.1 - 0.11 12.5 0.1 0.24 11.4 0.1 1.5 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) Trigger_N PF05697.13 AII57808.1 - 3.1e-35 121.6 5.8 3.1e-35 121.6 5.8 3.4 2 1 1 3 3 3 1 Bacterial trigger factor protein (TF) Trigger_C PF05698.14 AII57808.1 - 1.5e-27 96.6 16.9 1.5e-27 96.6 16.9 2.8 3 0 0 3 3 3 1 Bacterial trigger factor protein (TF) C-terminus OAM_alpha PF16552.5 AII57808.1 - 0.057 13.3 1.3 3.4 7.6 0.0 3.4 3 0 0 3 3 3 0 D-ornithine 4,5-aminomutase alpha-subunit DUF1053 PF06327.14 AII57808.1 - 0.11 13.1 10.5 7.5 7.2 0.0 4.6 4 1 0 4 4 4 0 Domain of Unknown Function (DUF1053) ACP_PD PF04336.12 AII57808.1 - 0.24 11.8 4.1 0.66 10.4 0.7 2.6 1 1 0 2 2 2 0 Acyl carrier protein phosphodiesterase DUF2408 PF10303.9 AII57808.1 - 0.41 11.2 7.0 1.2 9.7 5.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) CLP_protease PF00574.23 AII57809.1 - 2.4e-79 265.5 0.4 2.8e-79 265.2 0.4 1.0 1 0 0 1 1 1 1 Clp protease PGAP1 PF07819.13 AII57809.1 - 0.014 15.2 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein SDH_sah PF01972.16 AII57809.1 - 0.12 11.3 1.1 0.4 9.6 0.2 1.9 1 1 0 2 2 2 0 Serine dehydrogenase proteinase PfkB PF00294.24 AII57810.1 - 2.5e-35 122.3 0.1 9.8e-35 120.3 0.1 1.8 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Formyl_trans_N PF00551.19 AII57811.1 - 9.1e-15 54.9 0.0 1.6e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase PHP_C PF13263.6 AII57812.1 - 1.1e-13 50.7 0.0 2.5e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 PHP-associated PHP PF02811.19 AII57812.1 - 1.1e-08 35.6 0.0 3.2e-08 34.0 0.0 1.9 1 1 0 1 1 1 1 PHP domain Elong-fact-P_C PF09285.11 AII57813.1 - 1.5e-24 85.5 0.1 2.6e-24 84.7 0.1 1.4 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP PF01132.20 AII57813.1 - 1.6e-21 76.0 0.9 3.1e-21 75.2 0.9 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain EFP_N PF08207.12 AII57813.1 - 3.9e-17 62.0 0.3 1.6e-16 60.1 0.1 2.1 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain Peptidase_M24 PF00557.24 AII57814.1 - 7.3e-61 205.5 0.0 9.1e-61 205.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 AII57814.1 - 6.4e-23 81.9 0.0 9.9e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Pou PF00157.17 AII57814.1 - 0.13 12.3 0.0 2.6 8.1 0.0 2.4 2 0 0 2 2 2 0 Pou domain - N-terminal to homeobox domain Phage_integrase PF00589.22 AII57815.1 - 4.4e-50 169.8 0.0 6.1e-50 169.4 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 AII57815.1 - 6.9e-20 71.1 1.6 1.7e-19 69.9 0.2 2.2 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 AII57815.1 - 9.5e-08 32.4 0.3 9.5e-07 29.2 0.2 2.4 1 1 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 AII57815.1 - 1.3e-05 25.4 0.6 3.3e-05 24.1 0.6 1.6 1 0 0 1 1 1 1 Phage integrase SAM-like domain HTH_52 PF18576.1 AII57815.1 - 0.0019 18.3 0.5 0.0089 16.2 0.3 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain DUF3435 PF11917.8 AII57815.1 - 0.0038 16.2 0.1 0.0067 15.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Phage_integr_3 PF16795.5 AII57815.1 - 0.023 14.6 1.0 1.6 8.6 0.0 3.1 3 1 0 3 3 3 0 Archaeal phage integrase Integrase_1 PF12835.7 AII57815.1 - 0.027 14.6 0.1 0.078 13.1 0.1 1.7 1 1 0 1 1 1 0 Integrase Phage_int_SAM_6 PF18644.1 AII57815.1 - 0.037 14.1 0.4 0.11 12.5 0.4 1.8 1 1 0 1 1 1 0 Phage integrase SAM-like domain Topoisom_bac PF01131.20 AII57816.1 - 1.2e-132 442.9 6.1 1.7e-132 442.4 6.1 1.2 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 AII57816.1 - 7.7e-30 103.2 0.9 2.9e-29 101.3 0.2 2.4 2 0 0 2 2 2 1 Toprim domain zf-C4_Topoisom PF01396.19 AII57816.1 - 1.7e-22 78.9 29.9 5.8e-13 48.4 6.5 3.9 4 0 0 4 4 4 2 Topoisomerase DNA binding C4 zinc finger Toprim_4 PF13662.6 AII57816.1 - 0.0017 18.8 0.1 0.0086 16.5 0.1 2.3 1 1 0 1 1 1 1 Toprim domain zinc_ribbon_9 PF14369.6 AII57816.1 - 0.003 17.8 3.5 0.94 9.8 0.0 3.4 3 0 0 3 3 3 1 zinc-ribbon zf-ribbon_3 PF13248.6 AII57816.1 - 0.0063 15.9 10.7 0.22 11.0 3.2 3.6 3 0 0 3 3 3 1 zinc-ribbon domain Zn-ribbon_8 PF09723.10 AII57816.1 - 0.0093 16.1 11.3 3.8 7.7 0.2 4.4 4 0 0 4 4 4 2 Zinc ribbon domain RNA_POL_M_15KD PF02150.16 AII57816.1 - 0.0096 15.8 15.3 0.65 9.9 3.1 3.4 3 0 0 3 3 3 2 RNA polymerases M/15 Kd subunit DNA_ligase_ZBD PF03119.16 AII57816.1 - 0.032 14.2 9.4 0.66 10.0 0.5 3.5 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain Toprim_2 PF13155.6 AII57816.1 - 0.053 14.0 0.0 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 Toprim-like zinc-ribbons_6 PF07191.12 AII57816.1 - 0.092 12.7 14.7 0.56 10.2 5.7 2.5 2 0 0 2 2 2 0 zinc-ribbons Zn_Tnp_IS1 PF03811.13 AII57816.1 - 0.2 11.4 1.5 10 5.9 0.0 2.9 3 0 0 3 3 3 0 InsA N-terminal domain zf-RRN7 PF11781.8 AII57816.1 - 0.34 10.6 4.2 30 4.4 0.1 3.6 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DZR PF12773.7 AII57816.1 - 0.37 10.8 12.7 68 3.6 12.6 2.5 1 1 0 1 1 1 0 Double zinc ribbon Auto_anti-p27 PF06677.12 AII57816.1 - 0.67 10.2 7.7 9.4 6.5 1.4 3.3 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn_ribbon_recom PF13408.6 AII57816.1 - 0.81 10.3 23.0 0.31 11.6 1.1 3.8 4 0 0 4 4 3 0 Recombinase zinc beta ribbon domain YhfH PF14149.6 AII57816.1 - 1.8 8.6 7.7 4.9 7.2 0.1 3.4 3 0 0 3 3 3 0 YhfH-like protein DUF1272 PF06906.11 AII57816.1 - 3.5 7.8 6.5 26 5.0 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DNA_processg_A PF02481.15 AII57817.1 - 1.1e-78 263.3 0.0 1.4e-78 263.0 0.0 1.1 1 0 0 1 1 1 1 DNA recombination-mediator protein A DprA_WH PF17782.1 AII57817.1 - 5.9e-14 51.9 0.0 1.2e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 DprA winged helix domain LDcluster4 PF18306.1 AII57817.1 - 0.052 13.1 1.5 0.12 12.0 0.5 1.9 2 0 0 2 2 2 0 SLOG cluster4 family Na_H_Exchanger PF00999.21 AII57818.1 - 7.1e-68 229.1 53.5 9.7e-68 228.7 53.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3522 PF12036.8 AII57818.1 - 3.9 7.7 14.0 1.6 9.0 1.6 3.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3522) POR PF01558.18 AII57819.1 - 8.1e-41 140.0 0.4 9.6e-41 139.8 0.4 1.0 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Fer4 PF00037.27 AII57820.1 - 8.6e-12 44.4 18.5 3.5e-06 26.6 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 AII57820.1 - 3.8e-09 36.6 9.0 0.00024 21.2 2.4 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 AII57820.1 - 5.8e-09 35.9 10.4 9.8e-09 35.2 10.4 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 AII57820.1 - 1.7e-08 35.3 12.4 0.00021 22.1 2.5 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 AII57820.1 - 1.3e-07 32.0 25.0 2.9e-05 24.6 15.2 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AII57820.1 - 3.5e-07 29.9 8.1 0.0047 16.9 1.0 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 AII57820.1 - 7.5e-06 26.0 13.4 0.00025 21.1 14.0 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 AII57820.1 - 8.4e-06 26.2 8.1 0.02 15.4 1.7 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AII57820.1 - 1.4e-05 24.9 21.3 0.0075 16.3 5.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 AII57820.1 - 9.3e-05 22.6 15.6 0.0016 18.8 5.7 2.5 2 1 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 AII57820.1 - 0.00018 21.9 11.8 0.037 14.5 1.9 2.2 1 1 3 4 4 4 4 4Fe-4S dicluster domain Fer4_13 PF13370.6 AII57820.1 - 0.0082 16.7 10.7 0.079 13.5 2.3 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 AII57820.1 - 0.33 11.2 8.3 6 7.1 8.3 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 AII57820.1 - 0.41 11.5 15.0 1.1 10.1 2.3 2.3 1 1 2 3 3 3 0 4Fe-4S dicluster domain POR_N PF01855.19 AII57821.1 - 6.6e-67 225.6 0.1 8.2e-67 225.3 0.1 1.1 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PFOR_II PF17147.4 AII57821.1 - 2.8e-28 98.2 0.0 4.9e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 AII57821.1 - 2.4e-09 37.1 0.0 5.6e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.21 AII57822.1 - 5.2e-28 97.8 0.1 8.9e-28 97.0 0.1 1.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 2Fe-2S_thioredx PF01257.19 AII57823.1 - 4.4e-49 166.1 0.2 4.9e-49 165.9 0.2 1.0 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Glyoxalase_5 PF14696.6 AII57823.1 - 0.16 12.1 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Complex1_51K PF01512.17 AII57824.1 - 7.5e-45 152.5 0.0 1.7e-44 151.4 0.0 1.6 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 AII57824.1 - 7.9e-33 112.4 3.7 8.4e-33 112.3 0.1 2.5 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 2Fe-2S_thioredx PF01257.19 AII57824.1 - 2.9e-09 36.9 0.2 5.6e-09 36.0 0.2 1.4 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin SLBB PF10531.9 AII57824.1 - 7e-09 35.4 0.7 7e-09 35.4 0.7 2.4 3 0 0 3 3 3 1 SLBB domain Fer4 PF00037.27 AII57824.1 - 1.8e-08 33.8 24.3 2e-05 24.2 5.2 3.7 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_9 PF13187.6 AII57824.1 - 1.4e-07 31.6 10.1 1.4e-07 31.6 10.1 3.1 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 AII57824.1 - 1.1e-06 28.4 26.8 3.1e-05 23.8 4.3 4.1 4 0 0 4 4 3 2 4Fe-4S binding domain Fer4_10 PF13237.6 AII57824.1 - 0.0001 22.3 13.2 0.0001 22.3 13.2 3.2 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AII57824.1 - 0.00018 22.1 12.7 0.00018 22.1 12.7 3.5 3 1 1 4 4 3 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AII57824.1 - 0.0017 18.3 22.9 0.018 15.1 3.2 4.3 3 1 0 3 3 3 2 4Fe-4S binding domain Fer4_18 PF13746.6 AII57824.1 - 0.0025 18.0 5.8 0.0025 18.0 5.8 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 AII57824.1 - 0.0057 17.6 1.4 0.0057 17.6 1.4 3.7 3 0 0 3 3 2 2 4Fe-4S double cluster binding domain Fer4_22 PF17179.4 AII57824.1 - 0.024 15.5 6.1 0.47 11.3 0.6 2.9 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 AII57824.1 - 0.045 14.2 15.6 0.25 11.8 2.4 3.3 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 AII57824.1 - 0.068 13.3 23.6 0.06 13.5 4.9 3.7 3 1 0 4 4 3 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 AII57824.1 - 0.094 13.3 16.4 0.57 10.8 2.0 3.9 3 0 0 3 3 3 0 4Fe-4S dicluster domain Suc_Fer-like PF06999.12 AII57824.1 - 0.16 11.8 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 Sucrase/ferredoxin-like Fer4_4 PF12800.7 AII57824.1 - 3.5 8.4 26.7 0.89 10.2 3.6 4.4 4 0 0 4 4 4 0 4Fe-4S binding domain Fer2_4 PF13510.6 AII57825.1 - 1.4e-20 73.1 0.2 3.6e-20 71.8 0.2 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 AII57825.1 - 2.4e-08 34.4 23.8 3e-05 24.5 9.6 3.3 2 1 2 4 4 4 2 4Fe-4S dicluster domain Fer2 PF00111.27 AII57825.1 - 5.4e-08 32.7 0.4 5.4e-08 32.7 0.4 2.9 2 1 1 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 AII57825.1 - 2.7e-07 30.1 4.1 2.7e-07 30.1 4.1 4.5 6 0 0 6 6 5 2 4Fe-4S binding domain Fer4_21 PF14697.6 AII57825.1 - 6e-05 23.1 9.8 6e-05 23.1 9.8 3.1 3 1 1 4 4 4 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 AII57825.1 - 0.00022 21.4 10.5 0.00053 20.2 1.4 2.6 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AII57825.1 - 0.00054 20.0 5.4 0.00054 20.0 5.4 3.4 5 0 0 5 5 4 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AII57825.1 - 0.00093 19.2 30.2 0.0069 16.4 4.8 4.9 5 0 0 5 5 5 2 4Fe-4S binding domain Fer4_9 PF13187.6 AII57825.1 - 0.0032 17.6 8.8 0.0032 17.6 8.8 3.4 2 2 1 3 3 3 1 4Fe-4S dicluster domain Fer4_15 PF13459.6 AII57825.1 - 0.0034 18.1 7.0 0.86 10.4 1.4 3.0 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_2 PF12797.7 AII57825.1 - 0.0039 17.2 2.9 0.0039 17.2 2.9 4.8 5 0 0 5 5 5 2 4Fe-4S binding domain Fer4_4 PF12800.7 AII57825.1 - 0.011 16.2 3.3 0.011 16.2 3.3 4.9 6 1 0 6 6 4 0 4Fe-4S binding domain Fer4_13 PF13370.6 AII57825.1 - 0.029 14.9 1.4 0.029 14.9 1.4 3.2 3 0 0 3 3 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_16 PF13484.6 AII57825.1 - 0.033 15.1 21.9 0.08 13.9 9.1 3.3 3 1 0 3 3 2 0 4Fe-4S double cluster binding domain Fer4_8 PF13183.6 AII57825.1 - 0.19 12.2 22.4 0.28 11.7 2.1 3.2 2 2 0 3 3 3 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 AII57825.1 - 6.9 7.6 19.6 0.92 10.4 6.0 3.1 2 2 1 3 3 3 0 4Fe-4S dicluster domain Pyr_redox_2 PF07992.14 AII57826.1 - 3.4e-50 170.9 0.6 4.6e-50 170.5 0.6 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AII57826.1 - 2.6e-18 66.4 5.3 3.4e-12 46.8 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 AII57826.1 - 4.3e-16 59.1 0.0 9e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GIDA PF01134.22 AII57826.1 - 6.7e-11 41.9 12.2 2.2e-06 27.0 0.6 4.0 3 1 1 4 4 4 3 Glucose inhibited division protein A FAD_binding_2 PF00890.24 AII57826.1 - 1.4e-09 37.6 10.2 1.4e-06 27.6 2.5 3.8 2 1 2 4 4 4 3 FAD binding domain Pyr_redox_3 PF13738.6 AII57826.1 - 3.4e-09 36.4 2.5 1.6e-06 27.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AII57826.1 - 2.3e-08 33.8 8.2 2.1e-07 30.7 1.9 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 AII57826.1 - 7e-06 25.0 10.3 0.0026 16.5 1.5 3.8 3 1 1 4 4 4 2 HI0933-like protein NAD_binding_8 PF13450.6 AII57826.1 - 2.7e-05 24.3 6.8 0.0035 17.5 2.5 3.4 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AII57826.1 - 3.6e-05 23.5 1.4 0.00014 21.6 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 AII57826.1 - 0.00023 20.5 2.2 0.0062 15.8 0.9 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 AII57826.1 - 0.00096 18.4 0.3 0.18 10.9 0.0 2.6 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 AII57826.1 - 0.0024 17.1 1.2 0.32 10.2 0.3 2.4 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 AII57826.1 - 0.029 13.6 6.2 0.19 10.9 0.4 2.6 2 1 1 3 3 3 0 FAD binding domain Lycopene_cycl PF05834.12 AII57826.1 - 0.064 12.3 6.2 0.41 9.6 0.5 2.6 2 1 1 3 3 3 0 Lycopene cyclase protein Mqo PF06039.15 AII57826.1 - 0.14 10.7 0.4 0.49 8.9 0.1 1.8 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Trp_halogenase PF04820.14 AII57826.1 - 0.99 8.2 3.9 0.15 10.8 0.2 1.5 2 0 0 2 2 2 0 Tryptophan halogenase Zn-ribbon_8 PF09723.10 AII57827.1 - 2.7e-13 49.8 3.5 4e-13 49.2 1.7 2.1 2 0 0 2 2 2 1 Zinc ribbon domain GAGA PF09237.11 AII57827.1 - 0.027 14.3 1.0 0.052 13.4 1.0 1.4 1 0 0 1 1 1 0 GAGA factor HypA PF01155.19 AII57827.1 - 0.034 14.2 1.0 0.08 13.0 0.2 1.8 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2072 PF09845.9 AII57827.1 - 0.086 13.1 3.2 0.13 12.5 3.2 1.4 1 1 0 1 1 1 0 Zn-ribbon containing protein TF_Zn_Ribbon PF08271.12 AII57827.1 - 0.13 11.8 2.9 3.1 7.4 0.1 3.2 3 0 0 3 3 3 0 TFIIB zinc-binding zf_UBZ PF18439.1 AII57827.1 - 0.13 11.9 2.0 1.1 9.0 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_10 PF10058.9 AII57827.1 - 0.17 11.6 1.0 0.29 10.9 1.0 1.4 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein zinc_ribbon_4 PF13717.6 AII57827.1 - 0.27 11.2 3.8 2.4 8.1 3.8 2.4 1 1 0 1 1 1 0 zinc-ribbon domain zf-H2C2_2 PF13465.6 AII57827.1 - 0.48 10.9 3.6 3.7 8.2 0.8 2.4 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_6 PF13912.6 AII57827.1 - 0.76 9.9 5.6 3.4 7.8 2.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf_C2H2_10 PF18414.1 AII57827.1 - 0.92 9.1 3.1 10 5.7 0.7 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger zf-C2H2 PF00096.26 AII57827.1 - 1.6 9.4 3.9 4.8 7.8 1.0 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-ribbon_3 PF13248.6 AII57827.1 - 6.2 6.4 7.6 13 5.4 0.2 2.8 3 0 0 3 3 3 0 zinc-ribbon domain adh_short_C2 PF13561.6 AII57828.1 - 9.1e-60 202.1 5.0 1.2e-59 201.7 5.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AII57828.1 - 1e-55 188.2 4.0 1.4e-55 187.8 4.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AII57828.1 - 1.2e-10 41.6 1.0 1.9e-10 41.0 1.0 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 AII57828.1 - 0.013 15.4 2.3 0.021 14.7 2.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GTP-bdg_M PF16360.5 AII57829.1 - 1.9e-31 108.5 2.2 3.3e-31 107.7 2.2 1.4 1 0 0 1 1 1 1 GTP-binding GTPase Middle Region GTP-bdg_N PF13167.6 AII57829.1 - 6.4e-31 106.9 0.1 1.8e-30 105.4 0.1 1.8 1 0 0 1 1 1 1 GTP-binding GTPase N-terminal MMR_HSR1 PF01926.23 AII57829.1 - 4.9e-20 71.7 0.3 1.1e-19 70.6 0.3 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 AII57829.1 - 0.0001 22.4 1.2 0.00055 20.0 0.2 2.6 2 1 1 3 3 3 1 Dynamin family GTP_EFTU PF00009.27 AII57829.1 - 0.00023 20.8 0.2 0.0033 17.0 0.2 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 AII57829.1 - 0.00048 19.7 0.7 0.0068 16.0 0.1 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 AII57829.1 - 0.00076 19.0 0.6 0.0029 17.1 0.6 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.6 AII57829.1 - 0.0023 18.3 0.1 0.0061 17.0 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 AII57829.1 - 0.0024 17.8 0.4 0.18 11.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 AII57829.1 - 0.011 15.7 0.1 0.03 14.3 0.1 1.7 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain cobW PF02492.19 AII57829.1 - 0.013 15.1 2.2 1.1 8.9 0.2 2.5 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Gtr1_RagA PF04670.12 AII57829.1 - 0.054 12.8 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 AII57829.1 - 0.1 13.1 0.2 0.6 10.6 0.1 2.2 1 1 1 2 2 2 0 ABC transporter ECD PF18432.1 AII57829.1 - 0.12 12.3 0.3 1.5 8.8 0.0 2.6 3 0 0 3 3 3 0 Extracellular Cadherin domain Aminotran_1_2 PF00155.21 AII57831.1 - 4.3e-63 213.7 0.0 4.8e-63 213.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DAP_epimerase PF01678.19 AII57832.1 - 1.9e-48 163.6 0.0 4e-28 98.0 0.0 2.0 2 0 0 2 2 2 2 Diaminopimelate epimerase PhzC-PhzF PF02567.16 AII57832.1 - 4.3e-06 26.4 0.0 5.7e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein IPPT PF01715.17 AII57833.1 - 2.2e-67 227.2 0.1 2.6e-67 227.0 0.1 1.1 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 AII57833.1 - 1.4e-06 27.9 0.0 6.6e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 Isopentenyl transferase AAA_16 PF13191.6 AII57833.1 - 0.00027 21.4 0.1 0.0007 20.0 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AII57833.1 - 0.0038 17.5 0.0 0.0093 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF87 PF01935.17 AII57833.1 - 0.011 15.9 3.4 0.1 12.7 1.2 2.7 1 1 1 2 2 2 0 Helicase HerA, central domain ABC_tran PF00005.27 AII57833.1 - 0.011 16.2 0.0 0.029 14.9 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 AII57833.1 - 0.027 13.7 0.0 0.062 12.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 AII57833.1 - 0.03 14.3 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain CbtA_toxin PF06755.12 AII57833.1 - 0.046 13.7 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 CbtA_toxin of type IV toxin-antitoxin system DUF2075 PF09848.9 AII57833.1 - 0.053 12.8 0.1 0.15 11.3 0.1 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 AII57833.1 - 0.057 13.6 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 AII57833.1 - 0.059 12.6 0.1 0.12 11.5 0.1 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 AII57833.1 - 0.064 13.6 0.0 0.17 12.3 0.0 1.7 2 0 0 2 2 2 0 RNA helicase TIM PF00121.18 AII57834.1 - 1.8e-88 296.0 1.8 2.1e-88 295.8 1.8 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase PhosphMutase PF10143.9 AII57835.1 - 5e-44 150.2 0.0 7.5e-44 149.6 0.0 1.3 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.18 AII57835.1 - 3e-34 118.5 0.0 3.8e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Metalloenzyme superfamily PGK PF00162.19 AII57836.1 - 8.1e-149 495.7 0.2 9.2e-149 495.5 0.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PrpR_N PF06506.11 AII57836.1 - 0.025 14.2 0.2 0.82 9.2 0.0 2.8 2 1 1 3 3 3 0 Propionate catabolism activator DXP_synthase_N PF13292.6 AII57837.1 - 5.5e-113 376.7 0.1 1e-112 375.8 0.0 1.5 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 AII57837.1 - 1.9e-41 141.7 0.0 3.1e-41 141.0 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 AII57837.1 - 4.6e-24 84.7 0.0 1.1e-23 83.4 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transketolase_N PF00456.21 AII57837.1 - 1.1e-07 31.1 0.7 0.0018 17.3 0.4 2.6 2 1 0 2 2 2 2 Transketolase, thiamine diphosphate binding domain TPP_enzyme_C PF02775.21 AII57837.1 - 1.5e-06 28.1 0.2 0.00021 21.1 0.3 2.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 AII57837.1 - 1.3e-05 24.3 0.5 6.1e-05 22.1 0.2 1.9 2 0 0 2 2 2 1 Dehydrogenase E1 component PFOR_II PF17147.4 AII57837.1 - 0.015 15.6 0.0 0.038 14.3 0.0 1.7 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II Sm_multidrug_ex PF06695.11 AII57838.1 - 1.2e-36 126.0 4.0 1.2e-36 126.0 4.0 1.5 2 0 0 2 2 2 1 Putative small multi-drug export protein Pribosyltran PF00156.27 AII57839.1 - 1.8e-25 89.3 0.0 2e-25 89.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 AII57839.1 - 0.23 11.0 0.1 0.3 10.6 0.1 1.1 1 0 0 1 1 1 0 Phosphoribosyl transferase Ribosomal_L20 PF00453.18 AII57840.1 - 3.1e-39 133.3 2.0 3.6e-39 133.2 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L20 Ribosomal_L35p PF01632.19 AII57841.1 - 6.7e-18 65.0 6.5 7.3e-18 64.8 6.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L35 IF3_C PF00707.22 AII57842.1 - 2.3e-30 104.4 0.1 3.6e-30 103.8 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 AII57842.1 - 4.8e-30 103.6 0.1 8.1e-30 102.9 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain mIF3 PF14877.6 AII57842.1 - 0.025 14.3 0.1 0.039 13.6 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial translation initiation factor tRNA-synt_2b PF00587.25 AII57843.1 - 4e-39 134.4 0.0 8e-39 133.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 AII57843.1 - 7.9e-23 80.4 0.3 3.8e-22 78.2 0.2 2.1 2 0 0 2 2 2 1 Anticodon binding domain tRNA_SAD PF07973.14 AII57843.1 - 4.3e-15 55.5 0.0 7.7e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain SNARE PF05739.19 AII57844.1 - 0.74 9.9 4.3 52 4.0 0.2 4.4 2 0 0 2 2 2 0 SNARE domain RGS12_us2 PF16611.5 AII57845.1 - 3.8 8.0 9.7 0.27 11.6 0.4 3.3 3 0 0 3 3 3 0 Unstructured region between RBD and GoLoco zinc_ribbon_15 PF17032.5 AII57846.1 - 1.3e-18 67.5 6.3 1.7e-18 67.2 6.3 1.1 1 0 0 1 1 1 1 zinc-ribbon family DZR PF12773.7 AII57846.1 - 9e-07 28.8 5.3 9.2e-06 25.6 2.8 2.2 2 1 0 2 2 2 1 Double zinc ribbon HypA PF01155.19 AII57846.1 - 0.0013 18.8 9.9 0.0031 17.5 1.6 2.8 1 1 1 3 3 3 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ISL3 PF14690.6 AII57846.1 - 0.0052 17.4 13.2 0.39 11.4 0.0 3.8 3 1 0 3 3 3 2 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn-ribbon_8 PF09723.10 AII57846.1 - 0.014 15.5 13.5 3 8.0 0.1 3.6 3 1 0 3 3 3 0 Zinc ribbon domain Cytochrom_c3_2 PF14537.6 AII57846.1 - 0.018 15.5 4.1 0.037 14.5 4.1 1.6 1 1 0 1 1 1 0 Cytochrome c3 CxC3 PF18804.1 AII57846.1 - 0.049 13.5 5.6 0.13 12.2 0.7 2.2 1 1 1 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases DUF4187 PF13821.6 AII57846.1 - 0.059 13.2 0.2 0.059 13.2 0.2 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF4187) Cytochrome_C7 PF14522.6 AII57846.1 - 0.26 11.3 9.3 0.68 10.0 9.3 1.8 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c Tmemb_55A PF09788.9 AII57846.1 - 0.36 9.9 5.7 1.8 7.6 0.1 2.6 1 1 2 3 3 3 0 Transmembrane protein 55A DUF3797 PF12677.7 AII57846.1 - 0.59 10.1 8.0 27 4.7 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3797) zinc_ribbon_4 PF13717.6 AII57846.1 - 1.4 8.9 0.0 1.4 8.9 0.0 4.0 4 0 0 4 4 4 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 AII57846.1 - 1.6 8.3 14.3 0.59 9.7 1.5 3.0 2 2 0 2 2 2 0 TFIIB zinc-binding zf-ribbon_3 PF13248.6 AII57846.1 - 2.3 7.8 15.9 0.18 11.3 5.0 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zf-LITAF-like PF10601.9 AII57846.1 - 2.8 8.3 20.0 1.1 9.6 1.2 3.7 2 2 3 5 5 5 0 LITAF-like zinc ribbon domain Elf1 PF05129.13 AII57846.1 - 2.9 8.0 9.6 0.28 11.2 0.6 2.7 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.7 AII57846.1 - 3.2 7.8 16.3 3.6 7.6 4.1 3.7 3 1 0 3 3 3 0 Transposase zinc-ribbon domain Nudix_N_2 PF14803.6 AII57846.1 - 3.2 7.8 14.4 5.1 7.1 2.1 4.0 4 0 0 4 4 4 0 Nudix N-terminal Terminase_GpA PF05876.12 AII57846.1 - 3.8 5.9 5.3 1.6 7.2 3.0 1.5 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) zinc_ribbon_2 PF13240.6 AII57846.1 - 6.3 6.7 18.6 0.12 12.2 5.2 3.1 3 0 0 3 3 3 0 zinc-ribbon domain C1_4 PF07975.12 AII57846.1 - 6.8 7.0 15.2 4.3 7.6 2.9 3.2 1 1 2 3 3 3 0 TFIIH C1-like domain Cys_rich_KTR PF14205.6 AII57846.1 - 7.4 6.5 7.5 9.4 6.1 0.1 3.2 3 0 0 3 3 3 0 Cysteine-rich KTR RNA_POL_M_15KD PF02150.16 AII57846.1 - 9.2 6.2 21.4 1.4 8.9 4.3 3.6 4 0 0 4 4 4 0 RNA polymerases M/15 Kd subunit Ala_racemase_N PF01168.20 AII57847.1 - 7.1e-21 74.9 0.0 7.9e-21 74.7 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Orn_Arg_deC_N PF02784.16 AII57847.1 - 0.014 14.8 0.0 0.017 14.5 0.0 1.4 1 1 0 1 1 1 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain NAD_binding_3 PF03447.16 AII57847.1 - 0.094 13.4 0.0 0.17 12.6 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain HAD PF12710.7 AII57848.1 - 3.9e-15 56.7 0.0 5.7e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 AII57848.1 - 0.00016 21.2 0.0 0.0013 18.2 0.0 1.9 1 1 0 1 1 1 1 Putative Phosphatase HAD_2 PF13419.6 AII57848.1 - 0.0029 17.7 0.2 0.017 15.2 0.2 2.4 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 AII57848.1 - 0.016 15.5 0.1 0.34 11.2 0.1 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase NeuB PF03102.14 AII57848.1 - 0.058 12.8 0.0 0.078 12.4 0.0 1.1 1 0 0 1 1 1 0 NeuB family HSDR_N_2 PF13588.6 AII57848.1 - 0.077 13.0 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Hydrolase_6 PF13344.6 AII57848.1 - 0.14 12.3 0.1 0.61 10.2 0.0 2.2 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase VP4_helical PF17478.2 AII57848.1 - 0.2 11.1 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Rotavirus VP4 helical domain Pep_deformylase PF01327.21 AII57849.1 - 8.9e-48 161.9 0.0 1e-47 161.7 0.0 1.0 1 0 0 1 1 1 1 Polypeptide deformylase Heliorhodopsin PF18761.1 AII57850.1 - 1.5e-104 348.6 15.0 1.7e-104 348.4 15.0 1.0 1 0 0 1 1 1 1 Heliorhodopsin ABA_GPCR PF12430.8 AII57850.1 - 0.24 11.2 5.2 0.039 13.7 1.5 1.7 2 1 0 2 2 2 0 Abscisic acid G-protein coupled receptor DUF2177 PF09945.9 AII57851.1 - 6.9e-33 113.4 8.2 7.8e-33 113.2 8.2 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2177) CCB1 PF12046.8 AII57851.1 - 1.5 8.1 3.9 6.6 6.0 0.1 2.5 1 1 2 3 3 3 0 Cofactor assembly of complex C subunit B DLH PF01738.18 AII57852.1 - 3.2e-06 26.8 0.0 4.4e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 AII57852.1 - 1.1e-05 25.5 0.0 0.033 14.1 0.0 2.2 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 AII57852.1 - 3.1e-05 23.4 0.0 0.0076 15.5 0.0 2.8 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 AII57852.1 - 6.9e-05 22.6 0.0 0.00057 19.6 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 AII57852.1 - 0.00062 19.3 0.0 0.07 12.6 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 AII57852.1 - 0.0093 16.6 0.0 0.93 10.1 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 AII57852.1 - 0.046 13.5 0.0 3.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Cys_rich_KTR PF14205.6 AII57853.1 - 0.0098 15.7 0.3 0.0098 15.7 0.3 1.8 2 0 0 2 2 2 1 Cysteine-rich KTR Zn_Tnp_IS1595 PF12760.7 AII57853.1 - 0.034 14.1 2.0 0.059 13.4 2.0 1.5 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 AII57853.1 - 0.087 12.9 3.5 3.3 7.9 0.2 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-3CxxC PF13695.6 AII57853.1 - 0.1 13.1 3.6 0.38 11.3 3.6 1.8 1 1 0 1 1 1 0 Zinc-binding domain H_PPase PF03030.16 AII57854.1 - 1.5e-241 803.7 45.4 1.7e-241 803.5 45.4 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase DUF4190 PF13828.6 AII57855.1 - 2.7 7.8 13.6 56 3.6 13.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4190) DUF4870 PF09685.10 AII57856.1 - 1e-06 28.8 8.5 1.2e-06 28.5 8.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4870) Otopetrin PF03189.13 AII57856.1 - 0.43 9.3 6.7 0.18 10.6 4.5 1.5 1 1 1 2 2 2 0 Otopetrin CBS PF00571.28 AII57857.1 - 3.7e-21 75.3 0.0 4.1e-11 43.1 0.0 2.4 2 0 0 2 2 2 2 CBS domain Peptidase_M50 PF02163.22 AII57857.1 - 3.9e-14 52.5 11.3 4.2e-08 32.8 0.9 3.0 1 1 1 2 2 2 2 Peptidase family M50 SecE PF00584.20 AII57857.1 - 1.8 8.5 5.7 30 4.6 2.2 3.0 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex GreA_GreB PF01272.19 AII57858.1 - 9.3e-23 79.9 0.0 1.9e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term GreA_GreB_N PF03449.15 AII57858.1 - 4.2e-22 78.1 3.1 8.1e-22 77.2 3.1 1.5 1 0 0 1 1 1 1 Transcription elongation factor, N-terminal CPBP PF02517.16 AII57860.1 - 1.5e-14 54.1 5.7 1.5e-14 54.1 5.7 2.1 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease DUF3149 PF11346.8 AII57860.1 - 7.3 6.3 10.0 0.48 10.1 1.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3149) Peptidase_M50 PF02163.22 AII57861.1 - 3.1e-15 56.1 5.5 1.2e-08 34.6 0.1 2.8 1 1 1 2 2 2 2 Peptidase family M50 DUF3267 PF11667.8 AII57861.1 - 8.6e-05 22.8 0.6 0.00023 21.4 0.6 1.7 1 0 0 1 1 1 1 Putative zincin peptidase CBS PF00571.28 AII57861.1 - 0.00096 19.5 0.0 0.41 11.1 0.0 2.4 2 0 0 2 2 2 2 CBS domain Peptidase_M50B PF13398.6 AII57861.1 - 0.0042 16.8 2.9 0.0042 16.8 2.9 2.2 1 1 0 2 2 2 1 Peptidase M50B-like ThiC_Rad_SAM PF01964.18 AII57862.1 - 6.6e-198 657.6 0.1 7.5e-198 657.5 0.1 1.0 1 0 0 1 1 1 1 Radical SAM ThiC family GidB PF02527.15 AII57863.1 - 5.1e-44 149.8 0.0 6.3e-44 149.5 0.0 1.1 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.6 AII57863.1 - 5.3e-05 23.1 0.0 6.9e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 AII57863.1 - 0.07 13.1 0.0 0.12 12.4 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 AII57863.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain R3H PF01424.22 AII57864.1 - 2.6e-09 36.9 1.7 8.2e-09 35.3 1.2 2.1 2 0 0 2 2 2 1 R3H domain NTPase_1 PF03266.15 AII57864.1 - 3.3e-06 27.1 0.3 0.064 13.2 0.0 2.6 2 0 0 2 2 2 2 NTPase AAA_30 PF13604.6 AII57864.1 - 3.7e-06 26.8 0.5 7.4e-06 25.8 0.5 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 AII57864.1 - 8.8e-06 26.2 0.0 1.8e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AII57864.1 - 0.00012 22.1 0.0 0.00036 20.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 AII57864.1 - 0.00012 21.9 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 AII57864.1 - 0.00036 21.1 0.0 0.00097 19.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AII57864.1 - 0.00048 19.8 1.3 0.02 14.4 0.0 2.9 2 1 1 3 3 2 1 AAA domain AAA_16 PF13191.6 AII57864.1 - 0.00089 19.7 0.0 0.0024 18.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 AII57864.1 - 0.0023 18.2 0.2 0.015 15.6 0.2 2.2 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 AII57864.1 - 0.0092 16.0 0.2 0.023 14.7 0.1 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_7 PF12775.7 AII57864.1 - 0.0094 15.5 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region T2SSE PF00437.20 AII57864.1 - 0.011 14.8 1.6 0.023 13.8 1.6 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 AII57864.1 - 0.011 15.6 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 AII57864.1 - 0.016 15.3 0.0 0.046 13.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.27 AII57864.1 - 0.036 14.6 0.0 0.14 12.6 0.0 2.1 2 0 0 2 2 1 0 ABC transporter DnaB_C PF03796.15 AII57864.1 - 0.039 13.3 0.0 0.087 12.1 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain RuvB_N PF05496.12 AII57864.1 - 0.056 13.2 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain SRP54 PF00448.22 AII57864.1 - 0.059 13.0 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_31 PF13614.6 AII57864.1 - 0.063 13.2 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 AII57864.1 - 0.075 12.8 0.0 0.24 11.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 AII57864.1 - 0.075 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 AII57864.1 - 0.078 12.9 0.1 0.51 10.2 0.1 2.1 2 0 0 2 2 2 0 RsgA GTPase TsaE PF02367.17 AII57864.1 - 0.078 13.0 0.0 0.47 10.5 0.1 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 AII57864.1 - 0.079 12.8 0.0 0.24 11.2 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KdpD PF02702.17 AII57864.1 - 0.079 12.4 0.4 0.16 11.4 0.4 1.5 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain AAA_19 PF13245.6 AII57864.1 - 0.099 13.0 0.3 0.26 11.6 0.1 1.7 2 0 0 2 2 1 0 AAA domain NB-ARC PF00931.22 AII57864.1 - 0.11 11.7 0.1 0.25 10.5 0.1 1.5 1 0 0 1 1 1 0 NB-ARC domain TrwB_AAD_bind PF10412.9 AII57864.1 - 0.12 11.3 0.7 0.23 10.3 0.2 1.7 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ATPase_2 PF01637.18 AII57864.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MCM PF00493.23 AII57864.1 - 0.13 11.4 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain RNA_helicase PF00910.22 AII57864.1 - 0.16 12.4 0.0 0.41 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Thymidylate_kin PF02223.17 AII57865.1 - 3.4e-45 154.0 0.0 3.8e-45 153.8 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 AII57865.1 - 0.00015 22.1 0.0 0.0002 21.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AII57865.1 - 0.12 12.6 0.0 0.19 11.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain tRNA_Me_trans PF03054.16 AII57866.1 - 1.9e-103 346.0 0.0 2.3e-103 345.7 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.13 AII57866.1 - 3.1e-05 23.6 0.0 0.00071 19.1 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ThiI PF02568.14 AII57866.1 - 0.00013 21.6 0.1 0.00036 20.2 0.0 1.7 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.21 AII57866.1 - 0.015 15.0 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase Arginosuc_synth PF00764.19 AII57866.1 - 0.039 13.3 0.0 0.055 12.8 0.0 1.1 1 0 0 1 1 1 0 Arginosuccinate synthase NAD_synthase PF02540.17 AII57866.1 - 0.058 12.5 0.1 0.14 11.2 0.0 1.6 2 0 0 2 2 2 0 NAD synthase RNase_HII PF01351.18 AII57867.1 - 1.2e-31 110.1 0.0 1.4e-31 109.9 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease HII UPF0102 PF02021.17 AII57868.1 - 3.6e-22 78.4 0.0 4.2e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0102 NucS PF01939.16 AII57868.1 - 0.047 13.0 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 Endonuclease NucS ATPgrasp_Ter PF15632.6 AII57868.1 - 0.048 13.4 0.0 0.069 12.9 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon TMP-TENI PF02581.17 AII57869.1 - 4.6e-58 195.5 0.1 6e-58 195.1 0.1 1.2 1 0 0 1 1 1 1 Thiamine monophosphate synthase ThiD2 PF17792.1 AII57869.1 - 1.9e-36 125.3 0.5 2.9e-36 124.7 0.5 1.3 1 0 0 1 1 1 1 ThiD2 family Translin PF01997.16 AII57870.1 - 0.0026 17.8 0.1 0.0033 17.4 0.1 1.3 1 0 0 1 1 1 1 Translin family DUF1876 PF08962.11 AII57870.1 - 0.12 12.4 0.6 0.35 10.9 0.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1876) H_PPase PF03030.16 AII57871.1 - 1.4e-255 850.0 51.8 1.6e-255 849.8 51.8 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase PHP_C PF13263.6 AII57871.1 - 0.44 10.3 2.8 5.8 6.7 0.5 3.1 3 0 0 3 3 3 0 PHP-associated Lactamase_B PF00753.27 AII57872.1 - 7.1e-20 71.8 0.0 1.6e-19 70.7 0.0 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AII57872.1 - 1.6e-05 24.5 0.0 2.2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 AII57872.1 - 0.031 14.2 0.0 0.035 14.0 0.0 1.4 1 1 0 1 1 1 0 Beta-lactamase superfamily domain DUF1648 PF07853.11 AII57873.1 - 0.00014 21.5 0.3 0.00014 21.5 0.3 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1648) DUF2798 PF11391.8 AII57873.1 - 4.3 7.4 12.9 4.5 7.4 0.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2798) HGTP_anticodon PF03129.20 AII57874.1 - 1.3e-23 83.0 0.0 2.5e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 AII57874.1 - 5e-11 42.9 0.0 8.6e-11 42.1 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HypA PF01155.19 AII57874.1 - 0.0056 16.7 0.3 0.039 14.0 0.1 2.2 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RE_AccI PF09545.10 AII57874.1 - 0.1 11.5 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 AccI restriction endonuclease Lar_restr_allev PF14354.6 AII57874.1 - 0.16 12.3 1.6 3.6 8.0 0.0 2.5 1 1 1 2 2 2 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.7 AII57874.1 - 0.19 11.8 1.3 0.43 10.6 1.3 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 AII57874.1 - 0.31 11.2 2.4 0.83 9.8 2.2 1.8 1 1 0 1 1 1 0 Zinc ribbon domain Metallophos PF00149.28 AII57875.1 - 2.2e-14 54.5 0.0 3.5e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 AII57875.1 - 1.1e-10 41.9 0.0 1.6e-09 38.1 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PseudoU_synth_2 PF00849.22 AII57876.1 - 3.4e-17 63.0 0.0 8.2e-17 61.7 0.0 1.7 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 AII57876.1 - 6.2e-10 38.6 0.0 1.7e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 S4 domain Pribosyltran PF00156.27 AII57877.1 - 5.1e-21 74.8 0.5 2.7e-20 72.5 0.5 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 AII57877.1 - 0.0057 16.2 0.0 0.024 14.2 0.0 2.1 1 1 0 1 1 1 1 Phosphoribosyl transferase IMPDH PF00478.25 AII57877.1 - 0.0071 15.4 0.8 0.0093 15.0 0.8 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain UPRTase PF14681.6 AII57877.1 - 0.015 14.8 0.5 0.032 13.7 0.5 1.5 1 1 1 2 2 2 0 Uracil phosphoribosyltransferase Adenine_deam_C PF13382.6 AII57878.1 - 4.1e-68 228.0 0.1 6.2e-68 227.4 0.1 1.3 1 0 0 1 1 1 1 Adenine deaminase C-terminal domain Amidohydro_1 PF01979.20 AII57878.1 - 8.6e-22 77.9 0.2 2.7e-21 76.3 0.2 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AII57878.1 - 3.8e-07 29.9 1.0 6.3e-05 22.6 0.1 2.5 3 0 0 3 3 3 2 Amidohydrolase family Pribosyltran PF00156.27 AII57879.1 - 1.5e-25 89.5 0.0 1.8e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DZR PF12773.7 AII57880.1 - 0.0073 16.3 4.2 0.051 13.6 4.3 2.2 1 1 0 1 1 1 1 Double zinc ribbon TF_Zn_Ribbon PF08271.12 AII57880.1 - 0.016 14.7 4.7 0.2 11.2 1.9 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding A2L_zn_ribbon PF08792.10 AII57880.1 - 0.075 12.8 1.0 0.075 12.8 1.0 2.5 3 0 0 3 3 3 0 A2L zinc ribbon domain zinc_ribbon_15 PF17032.5 AII57880.1 - 0.088 13.6 6.9 0.49 11.2 0.9 2.4 2 0 0 2 2 2 0 zinc-ribbon family zf-ribbon_3 PF13248.6 AII57880.1 - 0.21 11.1 7.5 2.9 7.4 0.1 3.0 2 1 1 3 3 3 0 zinc-ribbon domain B12D PF06522.11 AII57880.1 - 0.54 10.1 4.6 1.1 9.1 1.0 2.7 2 1 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit zinc-ribbons_6 PF07191.12 AII57880.1 - 0.7 9.9 3.8 4.1 7.5 3.8 2.0 1 1 0 1 1 1 0 zinc-ribbons zf-C2HC_2 PF13913.6 AII57880.1 - 0.82 9.6 4.4 69 3.5 0.1 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Nudix_N_2 PF14803.6 AII57880.1 - 1.3 9.0 0.1 1.3 9.0 0.1 3.4 4 0 0 4 4 4 0 Nudix N-terminal Zn-ribbon_8 PF09723.10 AII57880.1 - 1.8 8.8 6.7 2.4 8.3 0.5 2.7 2 0 0 2 2 2 0 Zinc ribbon domain UPF0547 PF10571.9 AII57880.1 - 6.9 6.9 9.5 21 5.3 0.6 3.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 ABC_tran PF00005.27 AII57881.1 - 4.5e-29 101.7 0.1 7.1e-29 101.1 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AII57881.1 - 4.7e-14 52.9 0.0 1.6e-08 34.8 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AII57881.1 - 1.6e-05 24.5 0.1 0.0015 18.0 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 AII57881.1 - 4.8e-05 23.2 0.0 0.014 15.1 0.0 2.1 1 1 1 2 2 2 2 AAA ATPase domain DUF4162 PF13732.6 AII57881.1 - 0.0032 18.2 0.0 0.0084 16.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) AAA_23 PF13476.6 AII57881.1 - 0.017 15.6 0.1 0.037 14.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 AII57881.1 - 0.093 13.0 0.0 1.4 9.2 0.0 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit LPD18 PF18832.1 AII57881.1 - 0.095 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 18 AAA_13 PF13166.6 AII57881.1 - 0.1 11.2 0.0 0.79 8.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.7 AII57882.1 - 3.3e-51 174.4 21.2 3.7e-51 174.3 21.2 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 AII57882.1 - 2.8e-32 111.9 22.6 3.9e-32 111.4 15.9 2.2 2 0 0 2 2 2 2 ABC-2 type transporter ABC2_membrane_2 PF12679.7 AII57882.1 - 3.1e-12 46.4 13.3 4.1e-12 46.0 13.3 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 AII57882.1 - 0.0012 18.8 10.0 0.0012 18.8 10.0 2.2 2 1 0 2 2 2 1 ABC-2 family transporter protein Queuosine_synth PF02547.15 AII57883.1 - 1.5e-123 412.1 0.0 1.7e-123 411.9 0.0 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein SurE PF01975.17 AII57884.1 - 2.9e-55 187.1 0.0 3.6e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE tRNA_anti-like PF12869.7 AII57885.1 - 3.4e-13 49.5 0.1 4e-13 49.3 0.1 1.1 1 0 0 1 1 1 1 tRNA_anti-like MBG_2 PF18676.1 AII57885.1 - 0.0033 18.0 0.9 0.011 16.3 0.6 2.0 2 0 0 2 2 2 1 MBG domain (YGX type) DUF2520 PF10728.9 AII57886.1 - 1.7e-39 134.5 0.0 2.4e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2520) F420_oxidored PF03807.17 AII57886.1 - 9.1e-13 48.6 0.0 1.7e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 AII57886.1 - 1.3e-12 47.6 0.0 2.3e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Rossmann-like domain NAD_binding_2 PF03446.15 AII57886.1 - 9.1e-08 32.4 0.0 3.3e-07 30.6 0.0 1.8 1 1 1 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.22 AII57886.1 - 0.0007 20.4 0.0 0.0012 19.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.20 AII57886.1 - 0.0017 18.4 0.0 0.0027 17.8 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 AII57886.1 - 0.081 12.9 0.7 5.6 6.9 0.5 2.7 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PDH PF02153.17 AII57886.1 - 0.086 11.8 0.0 3.1 6.7 0.0 2.0 2 0 0 2 2 2 0 Prephenate dehydrogenase Semialdhyde_dh PF01118.24 AII57886.1 - 0.091 13.2 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain IlvN PF07991.12 AII57886.1 - 0.092 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 AII57886.1 - 0.12 11.8 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Asp_decarbox PF02261.16 AII57887.1 - 2e-48 163.1 0.2 2.3e-48 162.9 0.2 1.0 1 0 0 1 1 1 1 Aspartate decarboxylase Pantoate_transf PF02548.15 AII57888.1 - 2.8e-117 390.7 5.5 3.3e-117 390.5 5.5 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 AII57888.1 - 2.1e-07 30.6 0.9 1.1e-06 28.3 0.8 2.1 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Pantoate_ligase PF02569.15 AII57889.1 - 4.7e-103 344.0 0.0 5.3e-103 343.9 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase CTP_transf_like PF01467.26 AII57889.1 - 0.016 15.4 0.1 0.07 13.3 0.0 1.9 1 1 1 2 2 2 0 Cytidylyltransferase-like Avl9 PF09794.9 AII57889.1 - 0.037 12.7 0.0 0.049 12.3 0.0 1.2 1 0 0 1 1 1 0 Transport protein Avl9 MFS_1 PF07690.16 AII57890.1 - 3.7e-40 137.9 35.4 4.6e-20 71.8 9.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 AII57890.1 - 3e-10 39.6 20.1 1.4e-06 27.5 11.6 2.2 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 AII57890.1 - 4.1e-07 29.2 18.6 2e-06 26.9 10.9 2.6 2 1 0 2 2 2 2 MFS_1 like family MFS_2 PF13347.6 AII57890.1 - 7.1e-07 28.1 26.0 3.5e-06 25.8 21.9 2.7 1 1 1 2 2 2 1 MFS/sugar transport protein MFS_3 PF05977.13 AII57890.1 - 0.00022 19.8 6.9 0.00031 19.3 5.6 1.9 2 0 0 2 2 2 1 Transmembrane secretion effector ATG22 PF11700.8 AII57890.1 - 0.00027 19.7 13.7 0.00027 19.7 13.7 1.9 2 0 0 2 2 2 1 Vacuole effluxer Atg22 like PadR PF03551.14 AII57891.1 - 3.9e-18 65.2 0.8 5e-18 64.8 0.8 1.1 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_34 PF13601.6 AII57891.1 - 1.8e-05 24.8 0.0 2.3e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Winged helix DNA-binding domain RTP PF02334.16 AII57891.1 - 2.6e-05 24.8 0.0 3.1e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Replication terminator protein DUF4364 PF14277.6 AII57891.1 - 0.0054 16.5 0.0 0.0062 16.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) HTH_27 PF13463.6 AII57891.1 - 0.011 16.2 0.0 0.02 15.4 0.0 1.6 1 1 0 1 1 1 0 Winged helix DNA-binding domain HTH_45 PF14947.6 AII57891.1 - 0.017 15.1 0.1 0.024 14.6 0.1 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix Replic_Relax PF13814.6 AII57891.1 - 0.021 14.9 0.1 0.025 14.6 0.1 1.1 1 0 0 1 1 1 0 Replication-relaxation FUR PF01475.19 AII57891.1 - 0.06 13.5 0.0 0.068 13.3 0.0 1.1 1 0 0 1 1 1 0 Ferric uptake regulator family HTH_IclR PF09339.10 AII57891.1 - 0.065 13.1 0.5 0.22 11.3 0.5 1.9 1 1 0 1 1 1 0 IclR helix-turn-helix domain Amino_oxidase PF01593.24 AII57892.1 - 2.7e-22 79.7 0.0 4.4e-22 79.0 0.0 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 AII57892.1 - 1.3e-13 51.0 0.5 2.5e-13 50.1 0.5 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 AII57892.1 - 1.2e-05 25.0 0.2 0.00028 20.6 0.2 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 AII57892.1 - 0.00012 21.3 0.0 0.00022 20.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain MCRA PF06100.11 AII57892.1 - 0.0005 19.0 0.2 0.001 18.0 0.2 1.4 1 0 0 1 1 1 1 MCRA family Pyr_redox_2 PF07992.14 AII57892.1 - 0.00093 18.5 0.3 0.0049 16.1 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 AII57892.1 - 0.0014 17.8 0.3 0.011 14.8 0.2 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 AII57892.1 - 0.0032 16.7 0.1 0.0067 15.7 0.1 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 AII57892.1 - 0.0037 16.0 0.0 0.075 11.7 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 AII57892.1 - 0.0077 15.6 0.4 0.14 11.5 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 AII57892.1 - 0.015 14.6 0.1 0.036 13.3 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 AII57892.1 - 0.099 13.2 0.1 12 6.5 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 AII57892.1 - 0.19 11.0 0.2 0.44 9.8 0.3 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PAP2 PF01569.21 AII57893.1 - 7.1e-06 25.8 11.2 7.1e-06 25.8 11.2 3.0 2 1 0 3 3 3 1 PAP2 superfamily ThrE PF06738.12 AII57893.1 - 0.074 12.4 10.9 0.13 11.7 10.9 1.4 1 1 0 1 1 1 0 Putative threonine/serine exporter ABC_tran PF00005.27 AII57894.1 - 5.9e-29 101.3 0.0 7.7e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AII57894.1 - 8.4e-17 61.9 0.0 1.6e-09 38.0 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AII57894.1 - 5.3e-06 26.0 0.0 0.011 15.2 0.0 2.1 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 AII57894.1 - 0.00019 21.3 0.0 0.31 10.7 0.0 2.1 1 1 1 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 AII57894.1 - 0.0018 18.8 0.1 0.003 18.1 0.1 1.3 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 AII57894.1 - 0.013 15.1 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 AII57894.1 - 0.028 14.8 0.0 0.17 12.3 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 AII57894.1 - 0.032 14.0 0.1 0.066 13.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 AII57894.1 - 0.046 14.1 0.0 0.091 13.1 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 AII57894.1 - 0.05 13.5 0.0 0.06 13.3 0.0 1.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 AII57894.1 - 0.058 13.1 0.1 0.16 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AII57894.1 - 0.06 13.1 0.1 0.29 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 AII57894.1 - 0.13 12.6 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 AII57894.1 - 0.14 12.4 0.1 0.68 10.2 0.0 1.9 1 1 1 2 2 2 0 AAA domain MobB PF03205.14 AII57894.1 - 0.17 11.8 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC2_membrane PF01061.24 AII57895.1 - 3e-40 137.9 24.4 3e-40 137.9 24.4 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 AII57895.1 - 1.3e-27 96.9 24.9 1.3e-27 96.9 24.9 1.7 1 1 1 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 AII57895.1 - 5.2e-12 45.6 14.5 5.2e-12 45.6 14.5 2.1 1 1 1 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 AII57895.1 - 0.00042 20.3 17.4 0.00042 20.3 17.4 2.2 2 1 0 2 2 2 1 ABC-2 family transporter protein CcmB PF03379.13 AII57895.1 - 0.0024 17.4 11.6 0.0024 17.4 11.6 1.7 2 0 0 2 2 2 1 CcmB protein ABC2_membrane_5 PF13346.6 AII57895.1 - 0.14 11.7 23.1 0.38 10.3 23.1 1.9 1 1 0 1 1 1 0 ABC-2 family transporter protein ABC_tran PF00005.27 AII57896.1 - 8.9e-23 81.3 0.0 1.2e-22 80.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AII57896.1 - 1.9e-08 34.5 2.1 0.00069 19.5 0.2 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 AII57896.1 - 0.00065 20.2 1.0 0.0012 19.4 1.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 AII57896.1 - 0.00083 19.0 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_13 PF13166.6 AII57896.1 - 0.001 17.9 0.0 0.013 14.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 AII57896.1 - 0.0026 17.5 0.0 0.0048 16.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 AII57896.1 - 0.0026 17.2 0.2 0.024 14.1 0.2 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DLIC PF05783.11 AII57896.1 - 0.0053 15.7 0.0 0.0075 15.1 0.0 1.1 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) ATPase_2 PF01637.18 AII57896.1 - 0.019 14.9 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 AII57896.1 - 0.023 15.0 0.2 0.076 13.3 0.2 2.0 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 AII57896.1 - 0.025 13.6 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.19 AII57896.1 - 0.026 14.1 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 AII57896.1 - 0.03 14.3 0.0 0.074 13.1 0.0 1.7 1 1 1 2 2 2 0 AAA domain NACHT PF05729.12 AII57896.1 - 0.041 13.8 0.0 0.095 12.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_27 PF13514.6 AII57896.1 - 0.058 13.0 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 AII57896.1 - 0.082 12.6 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 AII57896.1 - 0.09 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 AII57896.1 - 0.14 11.9 0.2 0.31 10.7 0.1 1.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 AII57896.1 - 0.16 12.2 0.1 0.37 10.9 0.1 1.6 2 0 0 2 2 2 0 AAA domain UPF0051 PF01458.17 AII57897.1 - 6.9e-53 179.5 0.0 9.7e-53 179.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) ABC_tran PF00005.27 AII57898.1 - 3.4e-25 89.2 0.0 4.9e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AII57898.1 - 1.5e-08 34.8 4.1 0.0003 20.7 0.2 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 AII57898.1 - 1.1e-05 25.7 0.0 2.3e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 Helicase HerA, central domain SMC_N PF02463.19 AII57898.1 - 1.7e-05 24.4 1.2 0.026 14.0 0.1 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AII57898.1 - 0.00043 20.8 0.0 0.00061 20.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 AII57898.1 - 0.00063 19.6 2.8 0.28 10.8 0.3 2.1 1 1 1 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 AII57898.1 - 0.00075 19.2 0.0 0.0019 17.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 AII57898.1 - 0.0011 19.4 0.1 0.012 16.1 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 AII57898.1 - 0.0022 17.9 0.2 0.015 15.3 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase IstB_IS21 PF01695.17 AII57898.1 - 0.0032 17.2 0.3 0.068 12.9 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.6 AII57898.1 - 0.0048 17.2 1.3 0.1 12.9 1.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AII57898.1 - 0.0059 17.0 0.0 0.009 16.4 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 AII57898.1 - 0.012 15.7 0.0 0.042 13.9 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 AII57898.1 - 0.013 15.2 0.0 0.097 12.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 AII57898.1 - 0.022 14.0 0.1 0.076 12.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 AII57898.1 - 0.022 14.5 0.1 0.086 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 AII57898.1 - 0.035 13.6 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_27 PF13514.6 AII57898.1 - 0.036 13.6 0.1 0.077 12.6 0.0 1.5 2 0 0 2 2 2 0 AAA domain DUF4758 PF15950.5 AII57898.1 - 0.13 12.6 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative sperm flagellar membrane protein RNA_helicase PF00910.22 AII57898.1 - 0.14 12.6 0.0 0.33 11.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Thymidylat_synt PF00303.19 AII57899.1 - 2.9e-12 46.3 0.0 4.2e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Thymidylate synthase Flu_M1_C PF08289.11 AII57901.1 - 0.0065 16.7 0.6 0.015 15.5 0.6 1.6 1 0 0 1 1 1 1 Influenza Matrix protein (M1) C-terminal domain DUF1611_N PF17396.2 AII57901.1 - 0.034 14.4 0.0 0.12 12.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_N) Rossmann-like domain PSII_Pbs27 PF13326.6 AII57901.1 - 0.15 12.4 4.2 3.2 8.1 1.6 2.6 2 1 0 2 2 2 0 Photosystem II Pbs27 RNase_J_C PF17770.1 AII57901.1 - 0.19 12.8 0.8 0.39 11.8 0.1 1.9 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain DUF4810 PF16068.5 AII57901.1 - 0.21 12.1 5.8 0.16 12.5 1.8 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4810) WXG100 PF06013.12 AII57901.1 - 8.7 6.7 11.9 5.5 7.3 2.9 3.2 4 0 0 4 4 4 0 Proteins of 100 residues with WXG Archease PF01951.16 AII57902.1 - 1e-34 119.7 0.2 1.2e-34 119.6 0.2 1.0 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) RtcB PF01139.17 AII57903.1 - 1e-157 525.6 0.0 1.2e-157 525.4 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Nitroreductase PF00881.24 AII57904.1 - 1.7e-24 86.8 0.0 2e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 AII57904.1 - 2.6e-07 30.5 0.0 0.012 15.2 0.0 2.5 2 1 0 2 2 2 2 Putative TM nitroreductase HMGL-like PF00682.19 AII57905.1 - 8.5e-50 169.8 0.1 1.6e-49 168.9 0.1 1.4 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.10 AII57905.1 - 1.5e-24 86.4 0.0 1.7e-23 83.0 0.0 2.3 2 0 0 2 2 2 1 LeuA allosteric (dimerisation) domain PEP_mutase PF13714.6 AII57905.1 - 0.059 12.8 0.2 0.16 11.4 0.2 1.8 1 1 0 1 1 1 0 Phosphoenolpyruvate phosphomutase Bac_luciferase PF00296.20 AII57905.1 - 0.097 12.1 0.0 2.7 7.3 0.0 2.6 3 0 0 3 3 3 0 Luciferase-like monooxygenase Iso_dh PF00180.20 AII57906.1 - 2.9e-123 411.5 0.0 3.3e-123 411.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Aconitase_C PF00694.19 AII57907.1 - 4.9e-19 69.0 0.1 1.9e-18 67.0 0.1 1.7 1 1 1 2 2 2 1 Aconitase C-terminal domain Aconitase_2_N PF06434.13 AII57907.1 - 0.0014 18.3 0.0 0.0072 16.0 0.0 1.8 1 1 1 2 2 2 1 Aconitate hydratase 2 N-terminus Aconitase PF00330.20 AII57908.1 - 5.6e-101 338.8 0.9 7.9e-64 216.3 0.0 2.1 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) DUF521 PF04412.13 AII57908.1 - 0.0052 15.5 0.0 0.012 14.4 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF521) DUF1323 PF07037.11 AII57908.1 - 0.19 12.1 0.0 0.4 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative transcription regulator (DUF1323) MgtC PF02308.16 AII57909.1 - 7.4e-38 129.6 15.0 8.8e-38 129.4 15.0 1.0 1 0 0 1 1 1 1 MgtC family 7tm_3 PF00003.22 AII57909.1 - 0.059 13.1 2.5 0.13 12.0 2.5 1.6 1 1 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR HMGL-like PF00682.19 AII57910.1 - 1e-99 333.4 0.2 2.3e-99 332.2 0.2 1.6 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 AII57910.1 - 1.4e-38 131.8 0.2 2.4e-38 131.0 0.2 1.4 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain EFhand_Ca_insen PF08726.10 AII57910.1 - 0.095 12.8 0.5 1.1 9.5 0.1 2.3 2 0 0 2 2 2 0 Ca2+ insensitive EF hand Hydrolase_6 PF13344.6 AII57910.1 - 0.13 12.4 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase IlvN PF07991.12 AII57911.1 - 1.5e-71 239.3 1.6 2e-71 238.9 1.6 1.1 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 AII57911.1 - 2.4e-66 222.4 0.2 3.8e-66 221.8 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.19 AII57911.1 - 1.2e-08 34.5 0.1 2e-08 33.8 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 AII57911.1 - 7.2e-07 29.4 0.3 1.5e-06 28.3 0.3 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 AII57911.1 - 1.7e-05 25.1 0.3 3e-05 24.2 0.3 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 AII57911.1 - 2.7e-05 24.7 0.2 6.8e-05 23.4 0.2 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent CoA_binding PF02629.19 AII57911.1 - 0.0077 16.9 0.2 0.069 13.8 0.2 2.2 2 0 0 2 2 2 1 CoA binding domain Rossmann-like PF10727.9 AII57911.1 - 0.009 15.9 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 1 Rossmann-like domain GARS_N PF02844.15 AII57911.1 - 0.05 14.4 0.2 0.18 12.6 0.1 1.9 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain GFO_IDH_MocA PF01408.22 AII57911.1 - 0.15 12.9 0.1 0.3 11.9 0.1 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold ALS_ss_C PF10369.9 AII57912.1 - 1.7e-32 111.4 0.7 1.7e-32 111.4 0.7 1.9 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT_5 PF13710.6 AII57912.1 - 4.7e-19 68.0 0.6 4.2e-18 64.9 0.2 2.3 2 0 0 2 2 2 1 ACT domain ACT PF01842.25 AII57912.1 - 3.1e-14 52.4 0.6 6.4e-14 51.4 0.1 1.8 2 1 0 2 2 2 1 ACT domain ACT_4 PF13291.6 AII57912.1 - 0.00021 21.8 1.7 0.00039 21.0 0.2 2.0 2 1 0 2 2 2 1 ACT domain TPP_enzyme_N PF02776.18 AII57913.1 - 3.5e-55 186.2 0.2 1.1e-54 184.7 0.0 1.9 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 AII57913.1 - 9.3e-52 174.4 0.2 1.7e-51 173.6 0.2 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 AII57913.1 - 2e-51 173.8 0.2 5.2e-50 169.2 0.1 2.8 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.16 AII57913.1 - 0.0085 15.9 0.1 0.018 14.8 0.1 1.5 1 1 0 1 1 1 1 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit POR_N PF01855.19 AII57913.1 - 0.064 13.0 0.4 0.15 11.7 0.2 1.6 2 0 0 2 2 2 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg ILVD_EDD PF00920.21 AII57914.1 - 4.7e-221 734.9 2.5 5.3e-221 734.7 2.5 1.0 1 0 0 1 1 1 1 Dehydratase family Sua5_yciO_yrdC PF01300.18 AII57915.1 - 8.7e-53 178.5 0.0 1e-52 178.3 0.0 1.0 1 0 0 1 1 1 1 Telomere recombination SH3_12 PF18129.1 AII57915.1 - 0.024 14.7 0.1 0.045 13.9 0.1 1.4 1 0 0 1 1 1 0 Xrn1 SH3-like domain GMP_synt_C PF00958.22 AII57916.1 - 3.2e-45 152.1 0.3 7.4e-45 151.0 0.3 1.7 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 AII57916.1 - 5.6e-38 130.6 0.0 8.3e-38 130.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 AII57916.1 - 1.4e-09 37.4 0.1 2.4e-06 26.9 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 AII57916.1 - 5.5e-06 26.3 0.0 1.4e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 AII57916.1 - 0.0001 21.2 0.0 0.00018 20.4 0.0 1.4 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.13 AII57916.1 - 0.003 17.1 0.0 0.14 11.6 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ThiI PF02568.14 AII57916.1 - 0.0045 16.6 0.1 0.011 15.4 0.1 1.6 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) ATP_bind_3 PF01171.20 AII57916.1 - 0.011 15.5 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 0 PP-loop family PAPS_reduct PF01507.19 AII57916.1 - 0.011 15.7 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Asn_synthase PF00733.21 AII57916.1 - 0.014 15.1 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase GARS_A PF01071.19 AII57918.1 - 4e-75 251.9 0.0 5.8e-75 251.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 AII57918.1 - 8e-35 119.5 0.0 1.8e-34 118.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 AII57918.1 - 1.2e-27 96.0 0.1 7.5e-27 93.4 0.0 2.3 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain CPSase_L_D2 PF02786.17 AII57918.1 - 3e-05 23.6 0.1 4.9e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 AII57918.1 - 8.3e-05 22.7 0.0 0.00016 21.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_2 PF08442.10 AII57918.1 - 0.0003 20.4 0.0 0.00048 19.8 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 AII57918.1 - 0.0021 17.7 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 AII57918.1 - 0.0042 16.7 0.0 0.008 15.8 0.0 1.6 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 AII57918.1 - 0.0059 16.2 0.0 0.019 14.6 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain AIRC PF00731.20 AII57919.1 - 5.8e-59 197.9 0.7 6.4e-59 197.8 0.7 1.0 1 0 0 1 1 1 1 AIR carboxylase DAGK_cat PF00781.24 AII57919.1 - 0.076 12.6 0.0 0.23 11.1 0.0 1.8 1 1 0 1 1 1 0 Diacylglycerol kinase catalytic domain Lyase_1 PF00206.20 AII57920.1 - 5.8e-60 203.3 1.6 6.1e-60 203.2 0.5 1.5 2 0 0 2 2 2 1 Lyase ADSL_C PF10397.9 AII57920.1 - 5.9e-27 94.0 0.2 2.3e-26 92.1 0.1 2.1 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus T6SS_VasJ PF16989.5 AII57920.1 - 0.054 13.0 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ T2SSK PF03934.13 AII57920.1 - 0.066 12.6 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K SAICAR_synt PF01259.18 AII57921.1 - 1.1e-92 310.2 0.0 2.1e-92 309.3 0.0 1.4 2 0 0 2 2 2 1 SAICAR synthetase IGPD PF00475.18 AII57922.1 - 2.4e-52 177.1 0.5 3e-52 176.8 0.5 1.1 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Aminotran_1_2 PF00155.21 AII57923.1 - 1.8e-57 195.2 0.0 2e-57 195.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 AII57923.1 - 1e-07 31.2 0.0 1.4e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Allinase DegT_DnrJ_EryC1 PF01041.17 AII57923.1 - 2.2e-05 23.9 0.0 3.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 AII57923.1 - 0.0005 19.1 0.0 0.0034 16.4 0.0 2.1 2 1 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 AII57923.1 - 0.0037 15.9 0.0 0.0073 14.9 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Mad3_BUB1_I_2 PF17014.5 AII57923.1 - 0.032 14.3 0.0 0.059 13.5 0.0 1.4 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein HMG_box_5 PF14887.6 AII57923.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box 5 Histidinol_dh PF00815.20 AII57924.1 - 7.8e-154 512.6 5.3 9.6e-154 512.3 5.3 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase DUF5055 PF16478.5 AII57924.1 - 0.069 13.4 0.1 0.31 11.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5055) HisG PF01634.18 AII57925.1 - 8.6e-65 217.6 0.0 1.1e-34 119.7 0.0 2.1 2 0 0 2 2 2 2 ATP phosphoribosyltransferase tRNA-synt_His PF13393.6 AII57926.1 - 5.5e-63 213.1 0.0 6.7e-63 212.8 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase PGM_PMM_IV PF00408.20 AII57926.1 - 0.046 13.9 0.0 0.16 12.1 0.0 1.9 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain NfeD PF01957.18 AII57927.1 - 6.3e-17 61.7 0.5 8.5e-17 61.3 0.5 1.0 1 0 0 1 1 1 1 NfeD-like C-terminal, partner-binding Band_7 PF01145.25 AII57928.1 - 7.3e-32 110.8 3.9 9.7e-32 110.4 3.9 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 AII57928.1 - 8.5e-05 22.4 2.9 0.00023 21.0 2.9 1.6 1 1 0 1 1 1 1 SPFH domain-Band 7 family MIase PF02426.16 AII57928.1 - 0.31 11.2 2.3 1.9 8.7 0.7 2.5 2 0 0 2 2 2 0 Muconolactone delta-isomerase BPL_LplA_LipB PF03099.19 AII57929.1 - 9e-17 61.2 0.0 1.3e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 AII57929.1 - 3.1e-08 33.4 0.2 5.8e-08 32.5 0.2 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain BPL_LplA_LipB_2 PF16917.5 AII57929.1 - 0.011 15.3 0.0 0.22 11.1 0.0 2.1 1 1 0 1 1 1 0 Biotin/lipoate A/B protein ligase family LigD_N PF13298.6 AII57930.1 - 3.8e-39 133.2 0.0 5e-39 132.8 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase Ligase (LigD) ABC_tran PF00005.27 AII57931.1 - 1.6e-27 96.7 0.2 2.4e-27 96.1 0.2 1.3 1 0 0 1 1 1 1 ABC transporter DUF4162 PF13732.6 AII57931.1 - 2.9e-13 50.3 0.0 5.8e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) AAA_21 PF13304.6 AII57931.1 - 4.3e-11 43.2 1.3 4.6e-06 26.7 0.1 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AII57931.1 - 5.1e-05 23.7 0.0 8.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 AII57931.1 - 0.00015 21.3 1.8 0.032 13.7 0.1 2.6 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 AII57931.1 - 0.00016 21.5 0.4 0.16 11.6 0.0 2.2 1 1 1 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 AII57931.1 - 0.00017 21.9 0.3 0.00087 19.6 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 AII57931.1 - 0.00019 21.2 0.1 0.0018 18.0 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AII57931.1 - 0.0096 16.3 1.1 0.15 12.4 1.1 2.3 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.22 AII57931.1 - 0.014 15.0 0.1 0.021 14.5 0.1 1.5 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain TrwB_AAD_bind PF10412.9 AII57931.1 - 0.014 14.3 0.1 0.03 13.3 0.1 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_23 PF13476.6 AII57931.1 - 0.025 15.1 0.1 0.064 13.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AII57931.1 - 0.034 13.9 0.0 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 AII57931.1 - 0.037 13.8 0.2 0.11 12.3 0.2 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain PhoH PF02562.16 AII57931.1 - 0.072 12.5 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_27 PF13514.6 AII57931.1 - 0.099 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 AII57931.1 - 0.16 12.4 0.4 3.3 8.1 0.0 2.6 2 1 1 3 3 3 0 AAA domain AAA PF00004.29 AII57931.1 - 0.24 11.9 1.2 1.2 9.5 1.2 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC2_membrane_3 PF12698.7 AII57932.1 - 2.4e-44 151.9 19.0 2.9e-44 151.6 19.0 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 AII57932.1 - 3.4e-05 23.4 12.5 3.4e-05 23.4 12.5 2.6 2 1 1 3 3 3 1 ABC-2 type transporter DUF4719 PF15843.5 AII57932.1 - 0.69 10.0 2.7 5.7 7.0 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4719) FtsX PF02687.21 AII57935.1 - 1.1e-07 32.2 7.1 1.1e-07 32.2 7.1 3.0 3 0 0 3 3 3 1 FtsX-like permease family Phage_holin_3_6 PF07332.11 AII57935.1 - 3.1 7.8 11.2 0.29 11.2 3.9 2.5 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III ABC_tran PF00005.27 AII57936.1 - 4.1e-34 118.0 0.0 5.2e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AII57936.1 - 0.018 14.8 0.6 3.5 7.3 0.5 2.2 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AII57936.1 - 0.026 14.3 0.0 0.082 12.7 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 AII57936.1 - 0.048 14.0 0.3 0.083 13.3 0.3 1.6 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 AII57936.1 - 0.049 13.5 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase DUF2075 PF09848.9 AII57936.1 - 0.13 11.5 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 AII57936.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain HemN_C PF06969.16 AII57937.1 - 1.8e-16 60.0 0.0 3.3e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 HemN C-terminal domain Radical_SAM PF04055.21 AII57937.1 - 1.7e-13 51.3 0.0 2.5e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily GTP_EFTU PF00009.27 AII57938.1 - 8.9e-55 185.2 0.0 1.4e-54 184.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 AII57938.1 - 8.2e-46 154.6 1.9 1.4e-45 153.8 1.9 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 AII57938.1 - 3.9e-18 65.3 0.0 1.1e-17 63.8 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 AII57938.1 - 1e-05 25.5 0.0 4.2e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 AII57938.1 - 1.7e-05 24.9 0.0 3.7e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 AII57938.1 - 8.8e-05 22.8 1.6 0.00023 21.5 0.5 2.4 2 1 0 2 2 2 1 Elongation factor Tu domain 2 SRPRB PF09439.10 AII57938.1 - 0.0019 17.7 0.0 0.0043 16.5 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 AII57938.1 - 0.0085 15.7 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 AII57938.1 - 0.01 16.0 0.0 0.05 13.8 0.0 2.1 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 AII57938.1 - 0.025 13.9 0.2 0.1 11.9 0.0 2.0 2 0 0 2 2 2 0 Septin DUF4974 PF16344.5 AII57938.1 - 0.096 12.7 0.0 4.2 7.4 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4974) Proton_antipo_M PF00361.20 AII57939.1 - 4.9e-53 180.2 29.6 4.9e-53 180.2 29.6 3.4 2 1 2 4 4 4 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 AII57939.1 - 1e-15 57.6 3.3 2.4e-15 56.4 0.3 3.2 2 0 0 2 2 2 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus NADHdh PF00146.21 AII57940.1 - 2.6e-39 135.3 18.5 3.4e-39 134.9 18.5 1.1 1 0 0 1 1 1 1 NADH dehydrogenase DUF2721 PF11026.8 AII57940.1 - 0.0074 16.2 2.8 0.0074 16.2 2.8 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2721) YtpI PF14007.6 AII57940.1 - 3.3 7.9 8.4 0.38 10.9 2.5 2.4 2 1 0 2 2 2 0 YtpI-like protein Oxidored_q6 PF01058.22 AII57941.1 - 4e-26 91.4 2.6 4.9e-26 91.1 2.6 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit 2Fe-2S_thioredx PF01257.19 AII57942.1 - 2.7e-50 170.0 0.0 3e-50 169.8 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Complex1_51K PF01512.17 AII57943.1 - 5.5e-43 146.5 0.0 8.5e-43 145.8 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 AII57943.1 - 9.8e-31 105.7 0.1 9.8e-31 105.7 0.1 3.5 4 0 0 4 4 4 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Fer4 PF00037.27 AII57943.1 - 4.6e-11 42.1 22.3 2.1e-07 30.4 4.1 3.6 3 0 0 3 3 3 2 4Fe-4S binding domain SLBB PF10531.9 AII57943.1 - 4.4e-10 39.3 1.1 8.7e-10 38.3 1.1 1.5 1 0 0 1 1 1 1 SLBB domain Fer4_6 PF12837.7 AII57943.1 - 7.1e-08 32.2 15.1 9.5e-06 25.5 4.6 4.3 4 0 0 4 4 3 2 4Fe-4S binding domain Fer4_2 PF12797.7 AII57943.1 - 9.3e-08 31.7 21.3 0.00048 20.1 2.6 4.4 4 0 0 4 4 3 2 4Fe-4S binding domain Fer4_10 PF13237.6 AII57943.1 - 5.4e-06 26.4 26.2 0.00038 20.5 15.9 3.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 AII57943.1 - 3.1e-05 24.0 12.7 3.1e-05 24.0 12.7 3.9 4 1 1 5 5 4 2 4Fe-4S dicluster domain 2Fe-2S_thioredx PF01257.19 AII57943.1 - 9.9e-05 22.2 1.5 0.00019 21.3 1.5 1.4 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Fer4_15 PF13459.6 AII57943.1 - 0.00014 22.6 5.0 0.06 14.1 0.3 3.0 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_7 PF12838.7 AII57943.1 - 0.00014 22.4 14.6 0.00014 22.4 14.6 3.4 3 1 2 5 5 4 3 4Fe-4S dicluster domain Fer4_9 PF13187.6 AII57943.1 - 0.00021 21.4 13.8 0.00021 21.4 13.8 3.4 4 1 1 5 5 3 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 AII57943.1 - 0.00038 20.9 0.4 0.00038 20.9 0.4 3.3 3 0 0 3 3 2 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 AII57943.1 - 0.0039 17.4 6.0 0.011 15.9 6.0 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 AII57943.1 - 0.0061 17.0 0.6 0.0061 17.0 0.6 3.1 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 AII57943.1 - 0.0069 16.8 2.5 0.0069 16.8 2.5 4.4 5 0 0 5 5 3 1 4Fe-4S binding domain Fer4_16 PF13484.6 AII57943.1 - 0.019 15.9 2.0 0.019 15.9 2.0 3.2 3 0 0 3 3 2 0 4Fe-4S double cluster binding domain Suc_Fer-like PF06999.12 AII57943.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Sucrase/ferredoxin-like DUF1636 PF07845.11 AII57943.1 - 0.25 11.8 0.0 0.25 11.8 0.0 2.3 2 0 0 2 2 1 0 Protein of unknown function (DUF1636) Fer2_4 PF13510.6 AII57944.1 - 7e-19 67.7 0.6 1.3e-18 66.8 0.6 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 AII57944.1 - 6.2e-09 35.7 0.3 6.2e-09 35.7 0.3 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 AII57944.1 - 4.9e-06 26.1 17.4 0.0012 18.6 1.8 3.0 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_16 PF13484.6 AII57944.1 - 5e-05 24.1 9.5 0.00042 21.2 1.1 3.0 3 0 0 3 3 3 1 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 AII57944.1 - 6.2e-05 23.5 10.4 6.2e-05 23.5 10.4 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 AII57944.1 - 6.7e-05 23.4 7.3 0.03 14.9 1.4 2.9 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 AII57944.1 - 0.00015 21.9 8.4 0.00015 21.9 8.4 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AII57944.1 - 0.00017 21.6 11.2 0.0078 16.3 0.6 2.6 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AII57944.1 - 0.00094 19.3 15.1 0.003 17.7 12.0 2.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AII57944.1 - 0.0011 19.0 13.6 0.0027 17.7 0.7 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_8 PF13183.6 AII57944.1 - 0.023 15.2 13.4 0.027 14.9 11.4 2.1 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 AII57944.1 - 0.059 13.5 1.4 0.059 13.5 1.4 3.3 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_18 PF13746.6 AII57944.1 - 0.11 12.7 9.6 0.41 10.8 1.4 2.5 1 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 AII57944.1 - 0.11 13.0 19.9 0.63 10.7 2.0 3.5 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_15 PF13459.6 AII57944.1 - 0.4 11.5 10.8 2.5 8.9 1.2 2.8 3 0 0 3 3 2 0 4Fe-4S single cluster domain Fer4_13 PF13370.6 AII57944.1 - 0.41 11.2 12.1 2.7 8.6 3.8 2.4 1 1 1 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 AII57944.1 - 0.71 11.0 21.1 0.52 11.4 3.0 3.1 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_20 PF14691.6 AII57945.1 - 9.1e-17 60.9 5.2 2.7e-15 56.1 0.4 2.4 2 0 0 2 2 2 2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.14 AII57945.1 - 1.5e-16 60.5 0.7 2.6e-07 30.2 0.2 2.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 AII57945.1 - 4.1e-10 39.8 0.0 8.4e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 AII57945.1 - 9.6e-07 28.2 0.8 1.6e-06 27.5 0.4 1.6 2 0 0 2 2 2 1 FAD binding domain Complex1_30kDa PF00329.19 AII57945.1 - 1e-06 29.4 0.0 1.9e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Pyr_redox PF00070.27 AII57945.1 - 1.5e-06 28.7 0.4 1.5e-05 25.4 0.2 2.5 2 1 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 AII57945.1 - 2.6e-06 27.3 0.3 7.5e-05 22.5 0.1 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 AII57945.1 - 5.3e-06 25.8 0.1 1e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 AII57945.1 - 9e-06 24.6 0.9 6.1e-05 21.9 0.3 2.3 2 1 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 AII57945.1 - 1.6e-05 24.2 0.3 0.00099 18.3 0.1 2.7 3 0 0 3 3 3 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 AII57945.1 - 2.1e-05 24.0 0.1 0.002 17.5 0.0 2.4 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 AII57945.1 - 3.1e-05 23.4 0.3 8.9e-05 21.9 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 AII57945.1 - 0.00014 21.3 0.1 0.0002 20.8 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 AII57945.1 - 0.00035 19.9 1.0 0.0016 17.8 0.1 2.5 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 AII57945.1 - 0.0044 16.9 0.1 0.012 15.5 0.1 1.8 2 0 0 2 2 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 AII57945.1 - 0.0059 17.0 0.1 0.014 15.8 0.1 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding MCRA PF06100.11 AII57945.1 - 0.0095 14.8 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 MCRA family NAD_Gly3P_dh_N PF01210.23 AII57945.1 - 0.015 15.3 0.0 0.033 14.2 0.0 1.6 2 0 0 2 2 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.21 AII57945.1 - 0.022 14.0 0.1 0.039 13.2 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain YjeF_N PF03853.15 AII57945.1 - 0.039 13.9 0.3 0.081 12.8 0.0 1.7 2 0 0 2 2 1 0 YjeF-related protein N-terminus UDPG_MGDP_dh_N PF03721.14 AII57945.1 - 0.048 13.2 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PALP PF00291.25 AII57945.1 - 0.053 12.9 0.1 0.11 11.9 0.1 1.6 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme NAS PF03059.16 AII57945.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Nicotianamine synthase protein Trp_halogenase PF04820.14 AII57945.1 - 0.15 10.8 0.1 0.23 10.3 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Complex1_49kDa PF00346.19 AII57946.1 - 1.9e-60 204.3 0.0 4.3e-42 144.1 0.1 2.3 1 1 1 2 2 2 2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 AII57946.1 - 1.1e-11 44.4 5.0 3.1e-10 39.6 0.5 3.5 2 1 1 4 4 4 2 Nickel-dependent hydrogenase Fer4 PF00037.27 AII57947.1 - 1.2e-10 40.7 12.5 1.2e-05 24.9 3.2 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 AII57947.1 - 5.4e-10 38.9 12.5 8.8e-07 28.7 4.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AII57947.1 - 2.2e-08 34.6 11.3 3.5e-08 33.9 11.3 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AII57947.1 - 8.9e-08 32.2 11.1 1.4e-07 31.5 11.1 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AII57947.1 - 1.1e-07 31.8 10.0 1.6e-07 31.3 10.0 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 AII57947.1 - 5.5e-07 29.3 12.8 0.0011 19.0 1.9 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 AII57947.1 - 3.1e-06 28.0 12.7 0.00027 21.8 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_8 PF13183.6 AII57947.1 - 6.5e-06 26.5 6.5 0.022 15.2 0.3 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 AII57947.1 - 6.9e-05 22.9 8.8 0.031 14.4 0.3 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 AII57947.1 - 0.0034 17.9 12.7 0.15 12.6 2.1 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_3 PF12798.7 AII57947.1 - 0.0096 16.8 16.9 0.049 14.6 5.3 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_15 PF13459.6 AII57947.1 - 0.062 14.0 6.7 1.5 9.6 1.4 2.4 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_18 PF13746.6 AII57947.1 - 0.14 12.3 8.7 0.29 11.4 8.7 1.5 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 AII57947.1 - 4.7 8.1 12.1 1.3 9.9 1.4 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 AII57947.1 - 5.1 7.9 14.7 7.5 7.3 2.8 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain tRNA-synt_2 PF00152.20 AII57948.1 - 3.7e-48 164.2 0.1 4.9e-48 163.8 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 AII57948.1 - 0.00084 18.9 0.0 0.12 11.9 0.0 2.4 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) Elong-fact-P_C PF09285.11 AII57949.1 - 5.6e-19 67.6 0.6 5.6e-19 67.6 0.6 2.4 3 2 1 4 4 4 1 Elongation factor P, C-terminal EFP_N PF08207.12 AII57949.1 - 3.2e-18 65.5 0.1 1.2e-17 63.7 0.1 2.1 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain EFP PF01132.20 AII57949.1 - 9.4e-16 57.6 1.8 2.1e-15 56.5 0.9 2.1 2 0 0 2 2 2 1 Elongation factor P (EF-P) OB domain MarR PF01047.22 AII57950.1 - 1.1e-14 54.1 0.0 1.7e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 AII57950.1 - 1.8e-10 40.5 0.1 3.4e-10 39.7 0.1 1.5 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AII57950.1 - 8.2e-07 29.4 0.0 1.5e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_24 PF13412.6 AII57950.1 - 0.002 17.6 1.1 0.0026 17.3 0.1 1.7 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding FtsK_gamma PF09397.10 AII57950.1 - 0.0094 15.7 0.0 0.022 14.5 0.0 1.7 1 0 0 1 1 1 1 Ftsk gamma domain TrmB PF01978.19 AII57950.1 - 0.018 14.9 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB FeoC PF09012.10 AII57950.1 - 0.019 15.0 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 FeoC like transcriptional regulator HTH_IclR PF09339.10 AII57950.1 - 0.047 13.5 0.2 0.095 12.5 0.2 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_20 PF12840.7 AII57950.1 - 0.09 12.8 0.0 0.49 10.5 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain MMPL PF03176.15 AII57951.1 - 4.5e-125 417.0 15.4 1e-66 225.2 1.2 3.4 3 1 0 3 3 3 2 MMPL family ACR_tran PF00873.19 AII57951.1 - 0.00013 19.8 7.2 0.00013 19.8 7.2 2.8 2 1 0 3 3 3 2 AcrB/AcrD/AcrF family Sterol-sensing PF12349.8 AII57951.1 - 0.0011 18.8 14.0 0.12 12.2 2.7 2.8 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Pox_I3 PF04661.12 AII57951.1 - 0.024 13.8 0.1 0.073 12.2 0.0 1.7 2 0 0 2 2 2 0 Poxvirus I3 ssDNA-binding protein HTH_3 PF01381.22 AII57952.1 - 3.7e-12 46.1 0.1 7e-12 45.2 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 AII57952.1 - 7.9e-11 42.2 0.0 1.6e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 AII57952.1 - 9.7e-09 35.1 0.4 2.9e-08 33.6 0.2 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_26 PF13443.6 AII57952.1 - 2.1e-05 24.9 0.0 4.7e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 AII57952.1 - 0.0038 17.1 0.0 0.013 15.3 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.6 AII57953.1 - 1.1e-08 34.5 0.1 1.7e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 AII57953.1 - 1.2e-08 34.7 0.3 1.8e-08 34.2 0.3 1.2 1 0 0 1 1 1 1 HTH domain MarR_2 PF12802.7 AII57953.1 - 1.4e-07 31.3 0.1 2e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 MarR family TFIIE_alpha PF02002.17 AII57953.1 - 7.8e-06 25.7 0.0 1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 TFIIE alpha subunit Rrf2 PF02082.20 AII57953.1 - 8.1e-06 26.1 0.0 1.1e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator TrmB PF01978.19 AII57953.1 - 5.3e-05 23.0 0.0 7.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_23 PF13384.6 AII57953.1 - 7.2e-05 22.5 0.2 0.00012 21.7 0.2 1.4 1 0 0 1 1 1 1 Homeodomain-like domain MarR PF01047.22 AII57953.1 - 8.1e-05 22.5 0.9 0.00011 22.1 0.1 1.5 2 0 0 2 2 2 1 MarR family FaeA PF04703.12 AII57953.1 - 0.00018 21.8 0.2 0.00029 21.2 0.2 1.3 1 0 0 1 1 1 1 FaeA-like protein SgrR_N PF12793.7 AII57953.1 - 0.00045 20.4 0.0 0.0008 19.6 0.0 1.4 2 0 0 2 2 1 1 Sugar transport-related sRNA regulator N-term HTH_28 PF13518.6 AII57953.1 - 0.00047 20.2 0.2 0.00047 20.2 0.2 1.6 2 0 0 2 2 1 1 Helix-turn-helix domain HTH_34 PF13601.6 AII57953.1 - 0.00055 20.1 0.0 0.00079 19.6 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_27 PF13463.6 AII57953.1 - 0.00099 19.6 0.1 0.0014 19.1 0.1 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_AsnC-type PF13404.6 AII57953.1 - 0.001 18.9 0.2 0.0017 18.1 0.2 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain RepL PF05732.11 AII57953.1 - 0.0013 18.2 0.0 0.0014 18.1 0.0 1.1 1 0 0 1 1 1 1 Firmicute plasmid replication protein (RepL) HTH_Crp_2 PF13545.6 AII57953.1 - 0.0014 18.6 0.1 0.0022 17.9 0.1 1.3 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_39 PF14090.6 AII57953.1 - 0.0023 17.7 0.3 0.0033 17.1 0.3 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 AII57953.1 - 0.0024 17.6 0.1 0.0031 17.3 0.1 1.2 1 0 0 1 1 1 1 IclR helix-turn-helix domain Penicillinase_R PF03965.16 AII57953.1 - 0.0025 18.2 0.0 0.003 17.9 0.0 1.2 1 0 0 1 1 1 1 Penicillinase repressor HTH_36 PF13730.6 AII57953.1 - 0.0047 16.8 0.0 0.01 15.8 0.0 1.6 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_Mga PF08280.11 AII57953.1 - 0.0064 16.5 0.0 0.0097 15.9 0.0 1.3 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain DUF2250 PF10007.9 AII57953.1 - 0.007 16.5 0.1 0.01 15.9 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) HTH_9 PF08221.11 AII57953.1 - 0.0073 16.4 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 helix-turn-helix domain FeoC PF09012.10 AII57953.1 - 0.0073 16.4 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 FeoC like transcriptional regulator HTH_29 PF13551.6 AII57953.1 - 0.008 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_12 PF08461.10 AII57953.1 - 0.013 15.4 2.0 0.032 14.2 1.7 1.8 1 1 0 1 1 1 0 Ribonuclease R winged-helix domain Replic_Relax PF13814.6 AII57953.1 - 0.019 15.0 0.1 0.024 14.7 0.1 1.3 1 0 0 1 1 1 0 Replication-relaxation GntR PF00392.21 AII57953.1 - 0.021 14.5 0.1 0.029 14.0 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family DUF4423 PF14394.6 AII57953.1 - 0.024 14.4 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) HTH_DeoR PF08220.12 AII57953.1 - 0.025 14.3 0.1 0.036 13.8 0.1 1.2 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain PaaX PF07848.12 AII57953.1 - 0.027 14.7 0.0 0.045 14.0 0.0 1.3 1 0 0 1 1 1 0 PaaX-like protein Sigma70_r4 PF04545.16 AII57953.1 - 0.049 13.1 0.1 0.091 12.3 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Phage_rep_O PF04492.13 AII57953.1 - 0.051 14.2 0.1 0.09 13.4 0.0 1.4 2 0 0 2 2 1 0 Bacteriophage replication protein O HTH_54 PF18607.1 AII57953.1 - 0.064 13.3 0.0 0.098 12.7 0.0 1.3 1 0 0 1 1 1 0 ParA helix turn helix domain Put_DNA-bind_N PF06971.13 AII57953.1 - 0.074 13.1 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus HTH_13 PF11972.8 AII57953.1 - 0.079 13.0 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 HTH DNA binding domain Cdc6_C PF09079.11 AII57953.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain RNA_pol_Rpc34 PF05158.12 AII57953.1 - 0.11 11.8 0.1 0.14 11.5 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit RPA_C PF08784.11 AII57953.1 - 0.19 12.4 0.0 0.29 11.8 0.0 1.3 1 0 0 1 1 1 0 Replication protein A C terminal ArsB PF02040.15 AII57954.1 - 2.6e-49 168.7 27.4 3.1e-49 168.5 27.4 1.0 1 0 0 1 1 1 1 Arsenical pump membrane protein CitMHS PF03600.16 AII57954.1 - 1.5e-23 83.5 36.9 1.5e-23 83.5 36.9 1.5 1 1 0 1 1 1 1 Citrate transporter MFS_1 PF07690.16 AII57955.1 - 5.2e-31 107.9 45.9 1.2e-17 63.9 17.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 AII57955.1 - 3.8e-09 35.9 27.4 6e-09 35.2 27.4 1.3 1 0 0 1 1 1 1 MFS_1 like family MFS_3 PF05977.13 AII57955.1 - 0.18 10.2 10.3 0.31 9.4 1.7 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector Peptidase_M29 PF02073.15 AII57956.1 - 2.1e-99 333.1 0.0 2.3e-99 332.9 0.0 1.0 1 0 0 1 1 1 1 Thermophilic metalloprotease (M29) Pribosyltran PF00156.27 AII57957.1 - 9.7e-25 86.9 0.0 1.5e-23 83.0 0.0 2.0 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AII57957.1 - 0.0093 15.4 0.0 0.018 14.5 0.0 1.6 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 AII57957.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.7 1 1 0 1 1 1 0 Phosphoribosyl transferase Rubrerythrin PF02915.17 AII57958.1 - 4.8e-09 36.7 7.3 0.00078 19.9 0.2 2.0 1 1 0 2 2 2 2 Rubrerythrin Ferritin_2 PF13668.6 AII57958.1 - 4.5e-07 30.1 3.3 0.00059 20.0 0.1 2.1 1 1 1 2 2 2 2 Ferritin-like domain DUF3231 PF11553.8 AII57958.1 - 0.00069 19.3 0.3 0.0011 18.6 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3231) COQ7 PF03232.13 AII57958.1 - 0.0011 18.8 0.1 0.0023 17.7 0.1 1.7 1 1 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Herpes_Helicase PF02689.14 AII57959.1 - 0.072 11.0 0.0 0.094 10.6 0.0 1.1 1 0 0 1 1 1 0 Helicase PAC2 PF09754.9 AII57960.1 - 8.5e-21 74.9 0.0 1.1e-20 74.6 0.0 1.1 1 0 0 1 1 1 1 PAC2 family DUF3772 PF12607.8 AII57960.1 - 1.5 8.7 4.5 4.8 7.0 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) PAC2 PF09754.9 AII57961.1 - 1.6e-35 123.1 0.0 1.9e-35 122.8 0.0 1.1 1 0 0 1 1 1 1 PAC2 family NAD_binding_10 PF13460.6 AII57961.1 - 0.098 12.5 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding DUF2621 PF11084.8 AII57962.1 - 0.08 12.9 5.1 0.13 12.3 2.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2621) ApbE PF02424.15 AII57964.1 - 1.3 8.5 4.5 43 3.5 4.5 2.1 1 1 0 1 1 1 0 ApbE family Fer4 PF00037.27 AII57965.1 - 2.5e-14 52.4 12.4 1.4e-08 34.2 1.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain NIL PF09383.10 AII57965.1 - 3.4e-14 52.4 0.0 4.2e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 NIL domain Fer4_7 PF12838.7 AII57965.1 - 7.1e-10 39.3 11.4 2.1e-09 37.8 11.8 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AII57965.1 - 9.2e-10 38.5 11.4 1.5e-09 37.8 11.4 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 AII57965.1 - 1.3e-09 37.7 13.8 7.5e-06 25.8 2.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 AII57965.1 - 1.9e-09 37.5 9.9 2.9e-09 37.0 9.9 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 AII57965.1 - 3.2e-09 36.3 14.0 0.00011 22.1 4.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 AII57965.1 - 1.3e-07 31.7 23.4 5.5e-06 26.4 13.0 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AII57965.1 - 3.1e-07 30.7 5.9 0.00043 20.7 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AII57965.1 - 3.9e-06 27.7 13.1 0.00069 20.5 3.9 2.3 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_15 PF13459.6 AII57965.1 - 0.00021 21.9 7.2 0.18 12.5 0.6 2.6 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.7 AII57965.1 - 0.00021 22.0 19.9 0.0013 19.5 7.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 AII57965.1 - 0.00034 20.9 14.6 0.0014 19.0 2.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 AII57965.1 - 0.0004 20.9 13.4 0.019 15.5 3.1 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.6 AII57965.1 - 0.0018 18.4 11.0 0.0077 16.4 11.0 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_13 PF13370.6 AII57965.1 - 0.0055 17.2 14.2 0.025 15.1 2.7 2.3 1 1 1 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_22 PF17179.4 AII57965.1 - 0.043 14.6 12.2 0.74 10.7 1.6 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_11 PF13247.6 AII57965.1 - 0.066 13.3 6.4 0.1 12.8 6.4 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain IBD PF10416.9 AII57965.1 - 0.16 12.0 0.5 16 5.6 0.0 2.2 2 0 0 2 2 2 0 Transcription-initiator DNA-binding domain IBD HcyBio PF01837.16 AII57966.1 - 1.1e-144 481.6 0.0 1.3e-144 481.4 0.0 1.0 1 0 0 1 1 1 1 Homocysteine biosynthesis enzyme, sulfur-incorporation T2SSE PF00437.20 AII57967.1 - 3e-45 154.4 2.0 5.6e-45 153.5 0.2 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.6 AII57967.1 - 1.5e-05 25.2 0.5 5.5e-05 23.5 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 AII57967.1 - 4.7e-05 23.2 0.5 0.00074 19.3 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 AII57967.1 - 0.00012 21.7 0.0 0.00027 20.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AII57967.1 - 0.00024 21.7 0.8 0.0006 20.4 0.8 1.9 1 1 0 1 1 1 1 AAA domain DUF87 PF01935.17 AII57967.1 - 0.00053 20.2 0.3 0.0015 18.7 0.3 2.0 1 1 0 1 1 1 1 Helicase HerA, central domain AAA_18 PF13238.6 AII57967.1 - 0.00086 19.9 0.1 0.0025 18.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 AII57967.1 - 0.0013 18.8 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_7 PF12775.7 AII57967.1 - 0.0021 17.6 0.0 0.011 15.2 0.0 2.2 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_19 PF13245.6 AII57967.1 - 0.0024 18.2 1.0 0.0075 16.6 1.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AII57967.1 - 0.0025 18.2 0.1 0.01 16.3 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 AII57967.1 - 0.0026 17.1 0.0 0.011 15.0 0.0 2.0 1 1 0 1 1 1 1 Zeta toxin ATP_bind_1 PF03029.17 AII57967.1 - 0.0033 17.2 0.2 0.016 15.0 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 AII57967.1 - 0.0033 17.8 0.0 0.025 15.0 0.0 2.3 2 0 0 2 2 2 1 RNA helicase NTPase_1 PF03266.15 AII57967.1 - 0.0037 17.2 0.2 0.18 11.7 0.1 2.7 1 1 1 2 2 2 1 NTPase ABC_tran PF00005.27 AII57967.1 - 0.0051 17.3 0.1 0.01 16.4 0.1 1.8 1 1 0 1 1 1 1 ABC transporter AAA PF00004.29 AII57967.1 - 0.0076 16.7 0.1 0.023 15.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TK PF00265.18 AII57967.1 - 0.012 15.5 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Thymidine kinase TrwB_AAD_bind PF10412.9 AII57967.1 - 0.012 14.5 0.8 0.027 13.4 0.0 1.8 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain SRP54 PF00448.22 AII57967.1 - 0.017 14.7 0.6 0.049 13.3 0.1 2.1 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_14 PF13173.6 AII57967.1 - 0.018 15.1 0.0 0.042 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 AII57967.1 - 0.024 14.1 0.1 0.07 12.6 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_27 PF13514.6 AII57967.1 - 0.024 14.2 0.0 0.067 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 AII57967.1 - 0.026 14.4 0.8 0.089 12.7 0.0 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain ATPase_2 PF01637.18 AII57967.1 - 0.034 14.1 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea KTI12 PF08433.10 AII57967.1 - 0.034 13.6 0.1 0.19 11.1 0.0 2.0 2 0 0 2 2 2 0 Chromatin associated protein KTI12 PRK PF00485.18 AII57967.1 - 0.041 13.6 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Ploopntkinase3 PF18751.1 AII57967.1 - 0.062 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_33 PF13671.6 AII57967.1 - 0.077 13.1 0.3 0.15 12.2 0.3 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 AII57967.1 - 0.09 12.7 0.7 0.69 9.8 0.0 2.3 2 1 0 2 2 2 0 NACHT domain AAA_5 PF07728.14 AII57967.1 - 0.093 12.7 0.0 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 AII57967.1 - 0.17 11.7 0.0 0.38 10.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Oxidored_q4 PF00507.19 AII57968.1 - 5.6e-29 100.2 4.4 5.6e-29 100.2 4.4 1.5 1 1 1 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 DUF4870 PF09685.10 AII57968.1 - 0.026 14.6 2.0 0.026 14.6 2.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4870) Oxidored_q6 PF01058.22 AII57969.1 - 5.4e-22 78.0 0.0 7.6e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Complex1_30kDa PF00329.19 AII57970.1 - 5.4e-36 123.9 0.0 6.4e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Complex1_49kDa PF00346.19 AII57971.1 - 7.5e-97 323.6 0.0 3.7e-67 226.3 0.0 2.2 1 1 1 2 2 2 2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 AII57971.1 - 8.9e-05 21.6 0.0 0.00015 20.9 0.0 1.3 1 0 0 1 1 1 1 Nickel-dependent hydrogenase NADHdh PF00146.21 AII57972.1 - 2.3e-125 417.8 23.9 3e-125 417.5 23.9 1.1 1 0 0 1 1 1 1 NADH dehydrogenase Fer4 PF00037.27 AII57973.1 - 1.3e-13 50.1 13.3 9.8e-07 28.3 1.4 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AII57973.1 - 2.2e-11 44.2 7.9 4.8e-11 43.1 7.9 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AII57973.1 - 4.5e-10 39.5 19.9 1.3e-07 31.6 9.2 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AII57973.1 - 1.5e-08 34.7 6.3 1.5e-08 34.7 6.3 2.0 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 AII57973.1 - 2.3e-08 34.0 22.4 1.3e-06 28.4 11.5 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AII57973.1 - 1.1e-06 29.5 12.3 0.00077 20.4 1.2 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_6 PF12837.7 AII57973.1 - 1.5e-06 28.0 12.1 0.0013 18.7 3.8 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 AII57973.1 - 1.7e-05 24.6 13.6 0.0034 17.4 3.0 2.8 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_8 PF13183.6 AII57973.1 - 1.9e-05 25.0 7.4 1.9e-05 25.0 7.4 2.0 2 2 1 3 3 3 1 4Fe-4S dicluster domain Fer4_3 PF12798.7 AII57973.1 - 0.00011 22.8 18.7 0.004 18.0 4.3 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 AII57973.1 - 0.00086 19.6 12.9 0.035 14.6 1.9 2.8 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_18 PF13746.6 AII57973.1 - 0.00094 19.4 8.4 0.0091 16.2 0.4 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 AII57973.1 - 0.002 18.7 12.8 0.0054 17.2 9.9 2.5 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 AII57973.1 - 0.0066 17.0 9.2 0.29 11.7 3.7 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 AII57973.1 - 0.91 10.3 12.4 1.3 9.8 0.4 2.9 2 1 1 3 3 3 0 4Fe-4S single cluster domain Oxidored_q3 PF00499.20 AII57974.1 - 1.2e-29 102.9 18.2 1.5e-29 102.6 18.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 PhoLip_ATPase_C PF16212.5 AII57974.1 - 0.72 9.6 14.3 0.16 11.7 0.8 2.0 1 1 1 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal Dpy19 PF10034.9 AII57974.1 - 3.5 5.7 7.8 4.5 5.4 7.8 1.1 1 0 0 1 1 1 0 Q-cell neuroblast polarisation TMEM138 PF14935.6 AII57974.1 - 8.4 7.1 10.5 1.5 9.5 6.5 1.8 2 0 0 2 2 2 0 Transmembrane protein 138 Oxidored_q2 PF00420.24 AII57975.1 - 1.4e-21 76.1 9.7 1.6e-21 75.9 9.7 1.0 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Proton_antipo_M PF00361.20 AII57976.1 - 6e-86 288.3 25.7 1.2e-85 287.2 25.7 1.6 1 0 0 1 1 1 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 AII57976.1 - 3.8e-20 71.7 1.3 3.8e-20 71.7 1.3 3.2 2 0 0 2 2 2 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Proton_antipo_C PF01010.19 AII57976.1 - 1.2e-05 25.0 0.4 0.073 12.7 0.0 2.7 2 0 0 2 2 2 2 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus Proton_antipo_M PF00361.20 AII57977.1 - 6.9e-78 261.8 24.2 6.9e-78 261.8 24.2 1.8 1 1 1 2 2 2 1 Proton-conducting membrane transporter Oxidored_q5_N PF01059.17 AII57977.1 - 7.4 6.7 18.7 0.066 13.3 6.4 3.7 2 2 1 3 3 3 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus Proton_antipo_M PF00361.20 AII57978.1 - 1.1e-67 228.3 25.0 1.1e-67 228.3 25.0 2.1 1 1 1 2 2 2 1 Proton-conducting membrane transporter Oxidored_q5_N PF01059.17 AII57978.1 - 6.4e-06 26.2 2.4 6.4e-06 26.2 2.4 3.8 4 1 1 5 5 5 1 NADH-ubiquinone oxidoreductase chain 4, amino terminus TatD_DNase PF01026.21 AII57979.1 - 5.4e-74 248.8 0.0 6.1e-74 248.6 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_1 PF01979.20 AII57979.1 - 0.0026 17.1 0.5 0.0083 15.5 0.1 1.9 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_2 PF04909.14 AII57979.1 - 0.0095 15.7 0.2 0.15 11.8 0.0 2.6 2 1 0 2 2 2 1 Amidohydrolase UPF0489 PF12640.7 AII57979.1 - 0.02 15.1 0.1 0.03 14.6 0.1 1.3 1 0 0 1 1 1 0 UPF0489 domain HhH-GPD PF00730.25 AII57980.1 - 5.1e-21 75.2 0.0 7e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 AII57980.1 - 7.4e-07 28.7 0.0 1.8e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 AII57980.1 - 1.2e-05 25.4 5.6 1.9e-05 24.8 5.6 1.3 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III HHH_5 PF14520.6 AII57980.1 - 0.049 14.2 0.8 0.18 12.4 0.0 2.3 3 0 0 3 3 3 0 Helix-hairpin-helix domain 5_3_exonuc PF01367.20 AII57980.1 - 0.16 12.6 0.1 0.69 10.5 0.0 2.0 2 1 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold GATase_3 PF07685.14 AII57981.1 - 2.5e-55 187.1 0.1 3.5e-55 186.7 0.1 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AAA_26 PF13500.6 AII57981.1 - 3.8e-23 82.4 0.0 6.2e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 AII57981.1 - 9.4e-20 71.0 0.0 1.7e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.14 AII57981.1 - 0.0052 16.7 0.0 0.048 13.6 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF1611 PF07755.11 AII57981.1 - 0.0072 15.6 0.1 0.35 10.1 0.1 2.9 4 0 0 4 4 4 1 Domain of unknown function (DUF1611_C) P-loop domain GATase PF00117.28 AII57981.1 - 0.011 15.5 0.0 0.032 14.0 0.0 1.8 2 0 0 2 2 2 0 Glutamine amidotransferase class-I SNO PF01174.19 AII57981.1 - 0.046 13.6 0.0 0.096 12.5 0.0 1.5 1 0 0 1 1 1 0 SNO glutamine amidotransferase family Peptidase_S51 PF03575.17 AII57981.1 - 0.092 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 GATase_5 PF13507.6 AII57981.1 - 0.12 11.5 0.0 0.29 10.2 0.0 1.6 1 1 1 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain 4HBT PF03061.22 AII57982.1 - 1.6e-14 54.0 0.0 2e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 AII57982.1 - 4.9e-06 27.0 0.0 5.7e-06 26.8 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.6 AII57982.1 - 0.033 14.3 0.0 0.08 13.1 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4442) ABC_tran PF00005.27 AII57983.1 - 7.8e-30 104.2 0.0 1e-29 103.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter BCA_ABC_TP_C PF12399.8 AII57983.1 - 1.5e-10 40.8 0.0 2.7e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_23 PF13476.6 AII57983.1 - 6.1e-08 33.4 0.3 8.9e-08 32.9 0.3 1.3 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 AII57983.1 - 1.7e-06 28.0 0.1 2.1e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 AII57983.1 - 2.8e-06 27.4 3.3 4.4e-05 23.4 0.5 2.2 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AII57983.1 - 0.00032 20.2 0.1 0.00052 19.5 0.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AII57983.1 - 0.00066 19.6 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 AII57983.1 - 0.0011 18.6 0.1 0.002 17.8 0.1 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_27 PF13514.6 AII57983.1 - 0.019 14.6 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 AII57983.1 - 0.02 15.1 0.1 0.062 13.6 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AII57983.1 - 0.084 13.3 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 AII57983.1 - 0.091 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.8 AII57983.1 - 0.13 9.7 0.0 0.17 9.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) cobW PF02492.19 AII57983.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AMP-binding PF00501.28 AII57985.1 - 5.7e-16 58.1 0.1 1.1e-15 57.2 0.0 1.4 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C_2 PF14535.6 AII57985.1 - 0.0011 19.3 0.0 0.0024 18.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LuxE PF04443.12 AII57985.1 - 0.12 11.4 0.1 0.23 10.4 0.1 1.4 1 0 0 1 1 1 0 Acyl-protein synthetase, LuxE DUF3791 PF12668.7 AII57985.1 - 0.15 12.1 0.1 1.1 9.3 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3791) SUI1 PF01253.22 AII57985.1 - 0.17 12.4 1.3 1.4 9.5 0.1 2.4 1 1 1 2 2 2 0 Translation initiation factor SUI1 ABC_tran PF00005.27 AII57986.1 - 4.7e-25 88.7 0.0 8.4e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AII57986.1 - 3.3e-10 40.3 0.4 4.1e-05 23.6 0.3 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 AII57986.1 - 0.0023 17.6 0.1 0.0056 16.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AII57986.1 - 0.0025 18.4 0.7 0.0046 17.5 0.7 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AII57986.1 - 0.012 16.0 0.1 0.042 14.2 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 AII57986.1 - 0.013 15.1 0.1 0.024 14.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 AII57986.1 - 0.016 14.6 0.2 0.2 11.0 0.2 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 AII57986.1 - 0.018 14.8 0.7 0.032 13.9 0.7 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 AII57986.1 - 0.027 14.9 0.0 0.033 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain MukB PF04310.12 AII57986.1 - 0.038 13.8 0.0 0.053 13.3 0.0 1.2 1 0 0 1 1 1 0 MukB N-terminal AAA_15 PF13175.6 AII57986.1 - 0.041 13.6 0.1 0.11 12.1 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 AII57986.1 - 0.047 13.4 0.1 7.4 6.3 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 AII57986.1 - 0.084 13.1 0.5 0.15 12.3 0.5 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 AII57986.1 - 0.09 11.8 0.2 0.15 11.1 0.2 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 AII57986.1 - 0.2 11.9 0.4 0.53 10.5 0.4 1.9 1 1 0 1 1 1 0 AAA domain Peripla_BP_6 PF13458.6 AII57987.1 - 3.1e-65 221.1 0.0 3.5e-65 220.9 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 AII57987.1 - 1.3e-08 34.3 0.0 3.3e-08 33.0 0.0 1.6 1 1 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_5 PF13433.6 AII57987.1 - 0.0018 17.4 0.0 0.0063 15.5 0.0 1.9 3 0 0 3 3 3 1 Periplasmic binding protein domain Peripla_BP_2 PF01497.18 AII57987.1 - 0.04 13.5 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein Peripla_BP_6 PF13458.6 AII57988.1 - 6.4e-59 200.3 0.4 7.5e-59 200.1 0.4 1.0 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 AII57988.1 - 5.1e-07 29.1 0.0 7.3e-05 22.0 0.0 2.0 2 0 0 2 2 2 2 Receptor family ligand binding region Peripla_BP_5 PF13433.6 AII57988.1 - 0.0019 17.3 0.0 0.0034 16.4 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein domain BPD_transp_2 PF02653.16 AII57989.1 - 4.8e-38 130.9 40.7 8.1e-38 130.1 40.7 1.3 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component RAI1 PF08652.11 AII57989.1 - 0.087 13.0 0.1 0.44 10.8 0.0 2.1 2 0 0 2 2 2 0 RAI1 like PD-(D/E)XK nuclease BPD_transp_2 PF02653.16 AII57990.1 - 1.4e-35 122.8 38.9 1.6e-35 122.6 38.9 1.0 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component AMP-binding PF00501.28 AII57991.1 - 6.7e-76 255.6 0.0 8.2e-76 255.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme TPP_enzyme_C PF02775.21 AII57992.1 - 5.8e-27 94.4 0.5 1.3e-26 93.2 0.5 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain POR_N PF01855.19 AII57992.1 - 3.8e-17 62.8 2.6 5.5e-17 62.3 2.6 1.2 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Fer4 PF00037.27 AII57992.1 - 3.3e-05 23.5 7.0 0.0086 15.9 1.2 3.5 2 1 0 2 2 2 2 4Fe-4S binding domain TPP_enzyme_N PF02776.18 AII57992.1 - 0.0014 18.3 0.7 0.0014 18.3 0.7 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Fer4_21 PF14697.6 AII57992.1 - 0.0019 18.3 8.7 0.006 16.7 8.7 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 AII57992.1 - 0.003 17.6 15.9 0.027 14.6 1.3 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_6 PF12837.7 AII57992.1 - 0.0032 17.5 15.4 0.0046 17.0 0.9 3.1 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 AII57992.1 - 0.0053 16.8 10.5 0.15 12.2 2.5 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain DXP_synthase_N PF13292.6 AII57992.1 - 0.045 12.9 0.9 0.089 12.0 0.9 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Fer4_9 PF13187.6 AII57992.1 - 0.3 11.3 10.7 0.2 11.9 8.2 2.1 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 AII57992.1 - 2.4 8.8 13.2 0.76 10.4 3.0 2.7 1 1 1 2 2 2 0 4Fe-4S dicluster domain POR PF01558.18 AII57993.1 - 1.8e-40 138.9 0.1 2.1e-40 138.7 0.1 1.0 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase CBS PF00571.28 AII57994.1 - 4.6e-16 59.0 1.3 2.3e-08 34.3 0.1 3.0 3 0 0 3 3 3 2 CBS domain DUF1788 PF08747.11 AII57994.1 - 0.046 13.7 0.3 0.1 12.6 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1788) zf-ribbon_3 PF13248.6 AII57995.1 - 2.2e-05 23.7 22.5 0.00012 21.4 7.9 3.1 1 1 1 2 2 2 2 zinc-ribbon domain DZR PF12773.7 AII57995.1 - 0.067 13.2 17.2 0.47 10.5 17.1 2.2 1 1 1 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 AII57995.1 - 0.58 10.2 14.3 31 4.6 14.3 2.2 1 1 0 1 1 1 0 zinc-ribbons zf-LITAF-like PF10601.9 AII57995.1 - 1.1 9.6 16.5 0.44 10.9 0.8 3.1 1 1 2 3 3 3 0 LITAF-like zinc ribbon domain NifU_N PF01592.16 AII57996.1 - 6.1e-36 123.4 0.1 6.7e-36 123.3 0.1 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain TSCPD PF12637.7 AII57996.1 - 0.031 14.5 0.1 0.048 13.9 0.1 1.4 1 1 0 1 1 1 0 TSCPD domain SHOCT PF09851.9 AII57997.1 - 3.5e-11 42.5 0.5 4.5e-11 42.1 0.5 1.2 1 0 0 1 1 1 1 Short C-terminal domain Chordopox_A13L PF05961.11 AII57997.1 - 0.0019 18.4 0.0 0.0026 18.0 0.0 1.4 1 1 0 1 1 1 1 Chordopoxvirus A13L protein DUF1707 PF08044.11 AII57997.1 - 0.0024 17.9 0.0 0.0029 17.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1707) VbhA PF18495.1 AII57997.1 - 0.063 13.2 0.0 0.092 12.6 0.0 1.2 1 0 0 1 1 1 0 Antitoxin VbhA FtsH_ext PF06480.15 AII57997.1 - 0.077 13.4 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 FtsH Extracellular E1-E2_ATPase PF00122.20 AII57998.1 - 1.5e-56 190.8 0.2 6e-56 188.8 0.2 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 AII57998.1 - 2.7e-41 142.2 2.0 4.2e-41 141.5 2.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 AII57998.1 - 5.7e-25 87.5 0.0 1.7e-11 44.4 0.0 2.7 2 0 0 2 2 2 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 AII57998.1 - 3.1e-05 23.8 1.7 0.011 15.5 0.4 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase DUF2997 PF11211.8 AII57998.1 - 0.045 13.6 1.2 0.83 9.5 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2997) PhoD PF09423.10 AII57998.1 - 0.069 12.2 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 PhoD-like phosphatase HAD PF12710.7 AII57998.1 - 0.14 12.6 0.1 0.49 10.8 0.1 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HSP20 PF00011.21 AII57999.1 - 3e-25 88.3 0.1 3.9e-25 87.9 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 AII57999.1 - 1.5e-10 40.5 0.0 2.1e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA FKBP26_C PF18046.1 AII57999.1 - 0.0012 18.9 1.3 0.0066 16.5 0.2 2.1 2 0 0 2 2 2 1 FKBP26_C-terminal Ferritin PF00210.24 AII58000.1 - 1.4e-19 70.4 19.0 4.4e-12 46.1 2.4 2.9 2 1 0 2 2 2 2 Ferritin-like domain Rubrerythrin PF02915.17 AII58000.1 - 1.5e-12 48.1 14.2 7e-06 26.5 0.3 2.8 2 2 0 2 2 2 2 Rubrerythrin Ferritin_2 PF13668.6 AII58000.1 - 6.3e-12 45.9 1.9 1.6e-06 28.3 0.0 2.2 2 0 0 2 2 2 2 Ferritin-like domain Ferritin-like PF12902.7 AII58000.1 - 8.9e-12 45.4 1.0 1.4e-05 25.0 0.0 2.9 2 1 1 3 3 3 2 Ferritin-like COQ7 PF03232.13 AII58000.1 - 8.3e-06 25.7 11.2 0.58 9.9 0.1 4.1 3 1 1 4 4 4 4 Ubiquinone biosynthesis protein COQ7 Mn_catalase PF05067.12 AII58000.1 - 0.00042 19.4 9.2 0.063 12.2 0.2 3.9 1 1 3 4 4 4 2 Manganese containing catalase AAA_assoc_C PF09821.9 AII58000.1 - 0.03 14.9 6.9 1.5 9.4 1.1 2.9 1 1 2 3 3 3 0 C-terminal AAA-associated domain MetOD1 PF18546.1 AII58000.1 - 0.056 13.4 2.2 0.086 12.8 0.9 1.9 1 1 1 2 2 2 0 Metanogen output domain 1 Sod_Fe_C PF02777.18 AII58001.1 - 2.4e-24 85.4 0.4 3.8e-24 84.8 0.4 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 AII58001.1 - 0.0011 19.3 0.1 0.0026 18.2 0.1 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain zinc_ribbon_2 PF13240.6 AII58002.1 - 1.2e-05 24.9 4.1 2e-05 24.1 4.1 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 AII58002.1 - 0.00018 20.8 2.3 0.0003 20.1 2.3 1.4 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 AII58002.1 - 0.0015 18.5 0.9 0.0028 17.7 0.9 1.4 1 0 0 1 1 1 1 Double zinc ribbon APG6_N PF17675.1 AII58002.1 - 0.0093 16.5 0.0 0.012 16.1 0.0 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region ADIP PF11559.8 AII58002.1 - 0.017 15.2 3.1 0.029 14.5 3.1 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DHR10 PF18595.1 AII58002.1 - 0.026 14.6 0.2 0.042 13.9 0.2 1.2 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain ABC_tran_CTD PF16326.5 AII58002.1 - 0.032 14.5 0.7 0.091 13.0 0.7 1.8 1 0 0 1 1 1 0 ABC transporter C-terminal domain Spc7 PF08317.11 AII58002.1 - 0.046 12.6 0.8 0.067 12.1 0.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2374 PF09574.10 AII58002.1 - 0.049 13.4 0.5 0.11 12.3 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (Duf2374) CENP-F_leu_zip PF10473.9 AII58002.1 - 0.083 12.9 0.5 0.13 12.3 0.5 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RskA PF10099.9 AII58002.1 - 0.086 13.1 0.5 0.11 12.7 0.5 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA zinc_ribbon_15 PF17032.5 AII58002.1 - 0.12 13.1 2.1 0.27 12.0 2.1 1.6 1 0 0 1 1 1 0 zinc-ribbon family RNA_POL_M_15KD PF02150.16 AII58002.1 - 0.13 12.1 1.2 0.26 11.2 1.2 1.5 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit DUF4199 PF13858.6 AII58002.1 - 0.2 12.0 0.8 0.42 11.0 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Nudix_N_2 PF14803.6 AII58002.1 - 0.2 11.6 1.9 16 5.5 0.2 2.3 2 0 0 2 2 2 0 Nudix N-terminal CCDC144C PF14915.6 AII58002.1 - 0.24 10.5 3.7 0.32 10.1 3.7 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region THOC7 PF05615.13 AII58002.1 - 0.27 11.5 3.6 4.2 7.6 0.6 2.2 1 1 1 2 2 2 0 Tho complex subunit 7 HscB_4_cys PF18256.1 AII58002.1 - 0.3 10.9 1.2 0.65 9.9 1.2 1.6 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif Atg14 PF10186.9 AII58002.1 - 0.5 9.4 3.9 0.097 11.7 0.6 1.4 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 SlyX PF04102.12 AII58002.1 - 0.66 10.6 2.7 2.4 8.8 0.9 2.2 2 1 0 2 2 2 0 SlyX HAUS-augmin3 PF14932.6 AII58002.1 - 0.95 9.0 6.2 8.3 5.9 0.2 1.9 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 A2L_zn_ribbon PF08792.10 AII58002.1 - 1.9 8.3 4.4 18 5.2 4.4 2.4 1 1 0 1 1 1 0 A2L zinc ribbon domain DUF1385 PF07136.11 AII58003.1 - 0.032 13.5 0.4 0.048 13.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) DUF3810 PF12725.7 AII58003.1 - 0.05 13.0 0.1 0.068 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) SecE PF00584.20 AII58003.1 - 5.6 7.0 7.3 5.8 6.9 0.7 2.8 3 0 0 3 3 3 0 SecE/Sec61-gamma subunits of protein translocation complex Smr PF01713.21 AII58004.1 - 3.1e-14 53.1 0.1 3.8e-14 52.8 0.1 1.1 1 0 0 1 1 1 1 Smr domain His_biosynth PF00977.21 AII58005.1 - 7.2e-65 218.7 0.1 8.1e-65 218.5 0.1 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.15 AII58005.1 - 2.7e-08 33.6 0.9 0.00038 20.0 0.6 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase TMP-TENI PF02581.17 AII58005.1 - 9.4e-06 25.1 0.5 0.025 13.9 0.0 2.5 2 1 1 3 3 3 2 Thiamine monophosphate synthase ThiG PF05690.14 AII58005.1 - 1.7e-05 24.3 0.2 0.12 11.7 0.2 2.1 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG G3P_antiterm PF04309.12 AII58005.1 - 9.5e-05 21.9 0.2 0.043 13.2 0.0 2.4 2 0 0 2 2 2 2 Glycerol-3-phosphate responsive antiterminator Dus PF01207.17 AII58005.1 - 0.0001 21.5 0.0 0.095 11.8 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) IMPDH PF00478.25 AII58005.1 - 0.00043 19.4 2.6 0.43 9.5 1.1 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.21 AII58005.1 - 0.028 13.6 0.2 5.6 6.1 0.1 2.2 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase SBP_bac_3 PF00497.20 AII58005.1 - 0.11 11.8 0.1 0.24 10.8 0.1 1.5 1 1 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 NRD1_2 PF01995.16 AII58006.1 - 1.2e-86 289.9 0.0 1.5e-86 289.5 0.0 1.1 1 0 0 1 1 1 1 NrpR regulatory domains NRD1 and 2 HTH_12 PF08461.10 AII58006.1 - 2.6e-18 65.7 0.5 5.5e-18 64.7 0.5 1.6 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain UPF0004 PF00919.20 AII58007.1 - 1.6e-18 66.5 0.0 2.9e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 AII58007.1 - 1.8e-17 64.2 0.0 3.5e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Shufflon_N PF04917.12 AII58007.1 - 0.21 11.0 0.1 0.4 10.1 0.1 1.3 1 0 0 1 1 1 0 Bacterial shufflon protein, N-terminal constant region ketoacyl-synt PF00109.26 AII58008.1 - 2.7e-59 200.8 0.7 3.8e-59 200.3 0.3 1.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 AII58008.1 - 4.6e-36 123.4 1.0 8.5e-36 122.6 1.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 AII58008.1 - 3.9e-07 29.7 0.6 9.9e-06 25.1 0.1 2.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 AII58008.1 - 0.079 13.4 0.1 0.23 11.9 0.1 1.8 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension Thiolase_C PF02803.18 AII58008.1 - 0.12 12.1 3.5 3.8 7.2 0.2 3.3 3 1 1 4 4 4 0 Thiolase, C-terminal domain RecJ_OB PF17768.1 AII58009.1 - 6.4e-27 93.9 0.0 1.2e-26 93.1 0.0 1.4 1 0 0 1 1 1 1 RecJ OB domain DHHA1 PF02272.19 AII58009.1 - 1.4e-12 48.2 0.0 2.5e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 DHHA1 domain DHH PF01368.20 AII58009.1 - 1.9e-08 34.5 0.0 3.3e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 DHH family G3P_acyltransf PF02660.15 AII58010.1 - 1.3e-39 135.9 13.1 1.7e-39 135.5 13.1 1.1 1 0 0 1 1 1 1 Glycerol-3-phosphate acyltransferase LGT PF01790.18 AII58011.1 - 1.3e-50 171.9 16.5 1.5e-50 171.7 16.5 1.0 1 0 0 1 1 1 1 Prolipoprotein diacylglyceryl transferase Syndecan PF01034.20 AII58011.1 - 1.1 9.2 0.0 1.1 9.2 0.0 3.3 4 1 0 4 4 4 0 Syndecan domain Orai-1 PF07856.12 AII58011.1 - 5.3 6.7 8.5 0.64 9.7 2.4 2.1 2 0 0 2 2 2 0 Mediator of CRAC channel activity DEAD PF00270.29 AII58012.1 - 1.2e-24 87.0 0.0 2e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 AII58012.1 - 1e-22 80.6 0.0 2.4e-22 79.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 AII58012.1 - 1.4e-07 31.8 0.0 8.5e-07 29.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 AII58012.1 - 0.0014 18.6 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF503 PF04456.12 AII58013.1 - 2e-26 91.6 0.0 2.2e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF503) Ribosomal_S15 PF00312.22 AII58014.1 - 7.9e-33 112.5 0.6 9.4e-33 112.3 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S15 TIP39 PF14980.6 AII58014.1 - 0.13 12.2 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 TIP39 peptide RNase_PH PF01138.21 AII58015.1 - 7.7e-39 133.2 0.0 2.7e-24 86.1 0.0 2.6 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 AII58015.1 - 4e-23 81.2 0.8 9.9e-17 60.7 0.0 2.9 2 0 0 2 2 2 2 3' exoribonuclease family, domain 2 S1 PF00575.23 AII58015.1 - 3.2e-21 75.5 2.9 8.6e-21 74.1 2.9 1.8 1 0 0 1 1 1 1 S1 RNA binding domain KH_1 PF00013.29 AII58015.1 - 4.3e-10 39.3 2.6 4.3e-10 39.3 2.6 3.0 3 0 0 3 3 3 1 KH domain PNPase PF03726.14 AII58015.1 - 1.9e-08 34.7 4.1 2.6e-08 34.2 1.6 2.4 2 0 0 2 2 2 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain KH_4 PF13083.6 AII58015.1 - 0.00067 19.5 1.0 0.005 16.7 0.0 2.6 2 0 0 2 2 2 1 KH domain KH_2 PF07650.17 AII58015.1 - 0.035 13.9 0.6 0.035 13.9 0.6 2.6 2 1 1 3 3 3 0 KH domain Alg14 PF08660.11 AII58015.1 - 0.06 13.3 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like EXOSC1 PF10447.9 AII58015.1 - 0.18 12.4 2.1 2.2 8.9 0.2 2.9 2 0 0 2 2 2 0 Exosome component EXOSC1/CSL4 ExbD PF02472.16 AII58015.1 - 0.64 10.2 2.6 2.6 8.2 0.2 2.7 2 1 1 3 3 3 0 Biopolymer transport protein ExbD/TolR DapB_C PF05173.14 AII58016.1 - 4.9e-30 104.0 0.1 7.1e-30 103.5 0.1 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus DapB_N PF01113.20 AII58016.1 - 1e-26 93.5 0.0 1.7e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Glyco_trans_4_4 PF13579.6 AII58016.1 - 0.13 12.6 0.0 19 5.7 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Semialdhyde_dhC PF02774.18 AII58017.1 - 8.4e-56 189.0 0.0 1.2e-55 188.5 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 AII58017.1 - 5e-35 120.6 0.1 9.7e-35 119.6 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 AII58017.1 - 0.0025 17.9 0.1 0.0068 16.5 0.1 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.23 AII58017.1 - 0.0069 16.5 0.8 0.023 14.8 0.2 2.2 2 1 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 AII58017.1 - 0.072 13.4 0.0 0.19 12.0 0.0 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Gp_dh_C PF02800.20 AII58017.1 - 0.092 12.3 1.0 0.71 9.5 0.0 2.2 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Epimerase PF01370.21 AII58017.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DHDPS PF00701.22 AII58018.1 - 6.2e-99 330.3 0.1 7.5e-99 330.1 0.1 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Acetyltransf_7 PF13508.7 AII58019.1 - 2.1e-06 28.1 0.0 3.4e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AII58019.1 - 2.9e-06 27.2 0.0 4.5e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AII58019.1 - 3.3e-06 27.3 0.0 6.3e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 AII58019.1 - 1.4e-05 25.0 0.0 2.9e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 AII58019.1 - 9.3e-05 22.5 0.0 0.00066 19.8 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 AII58019.1 - 0.0013 18.3 0.0 0.0027 17.3 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase DUF1403 PF07183.11 AII58019.1 - 0.21 11.1 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1403) Acetyltransf_10 PF13673.7 AII58020.1 - 6.3e-09 35.8 0.0 8.5e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AII58020.1 - 3.4e-08 33.8 0.0 6.7e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AII58020.1 - 8e-08 32.5 0.0 1.3e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 AII58020.1 - 6.2e-07 29.6 0.0 3.1e-05 24.0 0.0 2.6 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AII58020.1 - 0.0041 17.2 0.0 0.0077 16.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 AII58020.1 - 0.0044 17.0 0.0 0.0084 16.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein NodA PF02474.15 AII58020.1 - 0.089 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein A (NodA) Gly_acyl_tr_C PF08444.10 AII58020.1 - 0.13 12.6 0.0 0.51 10.6 0.0 2.0 2 1 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Adenylsucc_synt PF00709.21 AII58021.1 - 1.3e-167 558.1 0.0 1.4e-167 557.9 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase CDP-OH_P_transf PF01066.21 AII58022.1 - 2.7e-15 56.9 4.0 2.7e-15 56.9 4.0 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase MASE3 PF17159.4 AII58022.1 - 0.053 13.1 5.0 0.02 14.5 2.4 1.6 1 1 0 1 1 1 0 Membrane-associated sensor domain Glycos_transf_1 PF00534.20 AII58023.1 - 5.9e-35 120.3 0.0 1.2e-34 119.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AII58023.1 - 3.2e-32 111.8 0.0 7.9e-32 110.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AII58023.1 - 1.2e-23 84.0 0.2 2.1e-23 83.2 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AII58023.1 - 2.5e-12 47.0 0.0 4.5e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 AII58023.1 - 6.5e-10 39.7 0.0 1.1e-09 39.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 AII58023.1 - 6.8e-09 35.9 0.0 1.6e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_transf_5 PF08323.11 AII58023.1 - 0.00061 19.6 0.1 0.025 14.3 0.0 2.3 1 1 1 2 2 2 1 Starch synthase catalytic domain PIGA PF08288.12 AII58023.1 - 0.16 12.6 0.7 8.1 7.1 0.1 2.6 1 1 1 2 2 2 0 PIGA (GPI anchor biosynthesis) DeoC PF01791.9 AII58023.1 - 0.16 11.5 0.0 1.8 8.1 0.0 2.1 2 0 0 2 2 2 0 DeoC/LacD family aldolase Inos-1-P_synth PF01658.17 AII58024.1 - 2.2e-34 118.0 0.0 1.7e-33 115.1 0.0 2.2 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase DNA_ligase_ZBD PF03119.16 AII58025.1 - 0.0094 16.0 1.2 0.018 15.0 0.2 1.8 2 0 0 2 2 2 1 NAD-dependent DNA ligase C4 zinc finger domain TruB_N PF01509.18 AII58026.1 - 2e-56 190.5 0.0 2.7e-56 190.1 0.0 1.2 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 AII58026.1 - 1.4e-10 41.2 0.0 2.6e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_C PF09142.11 AII58026.1 - 0.059 13.1 0.0 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal TruB-C_2 PF09157.11 AII58026.1 - 0.065 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Pseudouridine synthase II TruB, C-terminal RBFA PF02033.18 AII58027.1 - 7.9e-29 100.2 0.1 9e-29 100.0 0.1 1.0 1 0 0 1 1 1 1 Ribosome-binding factor A GTP_EFTU PF00009.27 AII58028.1 - 2.2e-36 125.3 0.8 8.7e-35 120.0 0.8 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 AII58028.1 - 7e-35 119.3 1.4 2.6e-34 117.5 1.4 2.1 1 0 0 1 1 1 1 Translation-initiation factor 2 IF2_N PF04760.15 AII58028.1 - 1.2e-10 41.0 0.2 3.5e-10 39.6 0.2 1.8 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.23 AII58028.1 - 6.4e-10 39.1 0.6 1.6e-09 37.8 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 AII58028.1 - 4e-08 33.5 0.3 0.002 18.5 0.0 3.4 3 0 0 3 3 3 2 Elongation factor Tu domain 2 Ras PF00071.22 AII58028.1 - 4.5e-06 26.4 0.0 1.1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Ras family Arf PF00025.21 AII58028.1 - 9.3e-06 25.2 0.0 2.9e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family FeoB_N PF02421.18 AII58028.1 - 9.6e-06 25.2 0.1 3.3e-05 23.5 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 AII58028.1 - 6e-05 22.6 0.1 0.00044 19.7 0.1 2.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 AII58028.1 - 0.00084 19.3 0.6 0.11 12.4 0.0 3.1 2 1 1 3 3 3 1 RsgA GTPase Roc PF08477.13 AII58028.1 - 0.0014 18.9 0.0 0.0025 18.0 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 AII58028.1 - 0.0052 15.8 0.8 0.14 11.1 0.1 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF448 PF04296.13 AII58029.1 - 7.5e-22 77.0 0.5 9.8e-22 76.6 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF448) FBP_C PF16571.5 AII58029.1 - 0.046 13.3 0.5 0.051 13.1 0.5 1.2 1 0 0 1 1 1 0 FBP C-terminal treble-clef zinc-finger NusA_N PF08529.11 AII58030.1 - 2.6e-32 111.7 3.7 2.6e-32 111.7 3.7 2.6 3 0 0 3 3 3 1 NusA N-terminal domain KH_5 PF13184.6 AII58030.1 - 2.1e-26 91.8 1.2 1.4e-25 89.2 0.1 2.7 2 0 0 2 2 2 1 NusA-like KH domain S1 PF00575.23 AII58030.1 - 2.3e-08 34.2 3.9 3.6e-08 33.6 0.7 2.8 2 0 0 2 2 2 1 S1 RNA binding domain KH_2 PF07650.17 AII58030.1 - 0.0013 18.5 1.4 0.0013 18.5 1.4 4.2 4 1 0 4 4 4 1 KH domain KH_1 PF00013.29 AII58030.1 - 0.071 13.0 0.2 0.96 9.3 0.0 2.5 2 0 0 2 2 2 0 KH domain Mg_chelatase PF01078.21 AII58031.1 - 7.7e-91 303.1 0.0 1.4e-90 302.2 0.0 1.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ChlI PF13541.6 AII58031.1 - 2.4e-46 156.5 0.0 4e-46 155.8 0.0 1.4 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Mg_chelatase_C PF13335.6 AII58031.1 - 5.2e-31 107.1 2.3 5.2e-31 107.1 2.3 1.7 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI C-terminal AAA_5 PF07728.14 AII58031.1 - 9.9e-09 35.3 0.0 1.1e-07 31.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 AII58031.1 - 1.3e-05 25.0 0.0 5.8e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain MCM PF00493.23 AII58031.1 - 2.1e-05 23.7 0.0 0.002 17.3 0.0 2.3 2 0 0 2 2 2 1 MCM P-loop domain RuvB_N PF05496.12 AII58031.1 - 7.3e-05 22.6 0.0 0.29 10.9 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 AII58031.1 - 0.00012 22.6 0.1 0.00066 20.1 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 AII58031.1 - 0.00055 19.1 0.0 0.00098 18.3 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 AII58031.1 - 0.00056 20.3 1.0 0.065 13.6 0.1 2.9 3 0 0 3 3 3 1 AAA domain AAA_32 PF13654.6 AII58031.1 - 0.0014 17.5 0.2 0.46 9.2 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 AII58031.1 - 0.0016 18.9 0.2 0.0053 17.2 0.0 1.9 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 AII58031.1 - 0.0027 18.0 0.0 0.015 15.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 AII58031.1 - 0.0029 17.8 0.3 0.027 14.6 0.0 2.6 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 AII58031.1 - 0.0072 16.2 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 AII58031.1 - 0.013 15.2 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 AII58031.1 - 0.014 15.1 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 AII58031.1 - 0.017 14.6 0.0 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_29 PF13555.6 AII58031.1 - 0.019 14.7 0.0 0.049 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.6 AII58031.1 - 0.021 15.0 0.0 0.092 12.9 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_2 PF07724.14 AII58031.1 - 0.048 13.8 0.0 0.51 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 AII58031.1 - 0.051 14.1 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 AII58031.1 - 0.07 12.3 0.1 0.15 11.2 0.1 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain FtsK_SpoIIIE PF01580.18 AII58031.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_11 PF13086.6 AII58031.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AII58031.1 - 0.14 12.7 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 AII58031.1 - 0.19 12.0 0.1 0.57 10.4 0.0 1.9 2 0 0 2 2 1 0 AAA domain DEAD PF00270.29 AII58031.1 - 0.2 11.4 0.0 0.46 10.2 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase TsaE PF02367.17 AII58031.1 - 0.21 11.6 0.0 0.46 10.5 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PIF1 PF05970.14 AII58031.1 - 0.22 10.7 0.0 0.39 9.8 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase Acetyltransf_3 PF13302.7 AII58032.1 - 3.1e-14 53.8 0.0 4.5e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AII58032.1 - 0.00087 19.5 0.1 0.0014 18.8 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 AII58032.1 - 0.027 14.6 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ApoLp-III PF07464.11 AII58032.1 - 0.054 13.6 1.7 0.1 12.7 1.7 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) ApoC-I PF04691.12 AII58032.1 - 0.059 13.3 1.4 0.4 10.6 1.4 2.3 1 1 1 2 2 2 0 Apolipoprotein C-I (ApoC-1) YtxH PF12732.7 AII58032.1 - 0.073 13.6 0.5 0.073 13.6 0.5 1.9 2 0 0 2 2 2 0 YtxH-like protein Histone_HNS PF00816.21 AII58032.1 - 0.3 11.9 1.4 22 6.0 0.3 2.4 1 1 1 2 2 2 0 H-NS histone family Acetyltransf_10 PF13673.7 AII58033.1 - 6.4e-20 71.4 0.1 7.2e-20 71.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AII58033.1 - 2.3e-10 40.7 0.0 3.3e-10 40.2 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AII58033.1 - 1.1e-09 38.6 0.0 1.3e-09 38.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 AII58033.1 - 5.2e-06 26.5 0.1 2e-05 24.7 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 AII58033.1 - 5.7e-06 27.0 0.5 9.3e-06 26.3 0.5 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AII58033.1 - 0.0097 15.9 0.0 0.016 15.1 0.0 1.4 1 1 0 1 1 1 1 FR47-like protein DUF502 PF04367.13 AII58034.1 - 1.1e-31 108.9 0.3 1.9e-31 108.1 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF502) Ribosomal_L12 PF00542.19 AII58035.1 - 2.7e-31 107.7 9.9 2.7e-31 107.7 9.9 1.9 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 AII58035.1 - 2e-17 62.6 14.5 4e-17 61.7 10.4 2.7 2 0 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain Ribosomal_60s PF00428.19 AII58035.1 - 0.0025 18.4 5.0 0.0025 18.4 5.0 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein DUF2805 PF10985.8 AII58035.1 - 0.13 12.7 0.2 0.25 11.7 0.1 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2805) GHMP_kinases_C PF08544.13 AII58035.1 - 0.72 10.3 5.0 0.99 9.8 1.2 2.5 1 1 1 2 2 2 0 GHMP kinases C terminal Ribosomal_L10 PF00466.20 AII58036.1 - 1.6e-23 82.8 0.1 2.4e-23 82.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_L1 PF00687.21 AII58037.1 - 1.2e-50 172.1 0.0 1.4e-50 171.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_L11_N PF03946.14 AII58038.1 - 2e-32 110.8 0.2 4e-32 109.8 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 AII58038.1 - 1.7e-23 82.9 2.4 3.3e-23 82.0 2.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain NusG PF02357.19 AII58039.1 - 1.5e-28 99.1 0.1 2.3e-28 98.5 0.1 1.3 1 0 0 1 1 1 1 Transcription termination factor nusG KOW PF00467.29 AII58039.1 - 1.1e-07 31.6 0.9 2.9e-07 30.2 0.9 1.7 1 0 0 1 1 1 1 KOW motif SecE PF00584.20 AII58040.1 - 1.5e-18 66.4 5.3 1.6e-18 66.4 4.7 1.3 2 0 0 2 2 2 1 SecE/Sec61-gamma subunits of protein translocation complex Ribosomal_L33 PF00471.20 AII58041.1 - 9.3e-21 74.0 4.7 1.1e-20 73.8 4.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 HypA PF01155.19 AII58041.1 - 0.016 15.2 1.2 0.019 14.9 1.2 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_2 PF13240.6 AII58041.1 - 0.031 14.0 3.9 1.5 8.6 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 AII58041.1 - 0.045 13.9 3.8 0.1 12.7 3.8 1.5 1 1 0 1 1 1 0 Zinc ribbon domain Ribosomal_L44 PF00935.19 AII58041.1 - 0.085 13.3 4.8 0.23 11.9 0.5 2.1 1 1 1 2 2 2 0 Ribosomal protein L44 GTP_EFTU PF00009.27 AII58042.1 - 2.7e-56 190.2 0.0 3.6e-56 189.8 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 AII58042.1 - 1.6e-28 99.2 0.3 1e-27 96.6 0.0 2.4 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 AII58042.1 - 3.1e-18 65.9 2.2 4.4e-18 65.4 1.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AII58042.1 - 2.6e-05 24.3 0.0 5.4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 AII58042.1 - 0.008 15.8 1.1 0.013 15.1 0.0 1.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 AII58042.1 - 0.014 15.3 0.2 0.043 13.7 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase ATP_bind_1 PF03029.17 AII58042.1 - 0.17 11.7 0.5 2.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 AII58042.1 - 0.18 11.6 0.1 9.5 6.0 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PIG-L PF02585.17 AII58043.1 - 3e-31 108.8 0.0 4.1e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Glycos_transf_1 PF00534.20 AII58044.1 - 5.8e-41 139.9 0.0 1.4e-40 138.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 AII58044.1 - 1.2e-31 109.9 0.0 2.9e-31 108.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AII58044.1 - 1e-27 97.2 0.4 1.5e-27 96.6 0.1 1.4 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AII58044.1 - 9.3e-21 74.9 0.0 1.3e-20 74.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 AII58044.1 - 4.2e-06 27.1 0.0 9.6e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 AII58044.1 - 0.012 15.3 0.5 0.88 9.2 0.5 2.2 1 1 0 1 1 1 0 Starch synthase catalytic domain Acetyltransf_6 PF13480.7 AII58045.1 - 2.1e-28 99.2 0.0 3.9e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HTH_5 PF01022.20 AII58046.1 - 9.2e-16 57.4 1.1 2.1e-15 56.3 0.7 1.8 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 AII58046.1 - 5.3e-14 52.0 0.1 9.7e-14 51.2 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 AII58046.1 - 1.3e-06 27.9 0.2 4.1e-06 26.3 0.2 1.8 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding LexA_DNA_bind PF01726.16 AII58046.1 - 3.9e-05 23.3 0.1 0.033 14.0 0.1 2.2 1 1 1 2 2 2 2 LexA DNA binding domain MarR_2 PF12802.7 AII58046.1 - 4.8e-05 23.2 0.1 8.5e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 AII58046.1 - 0.00022 20.9 0.1 0.00047 19.9 0.1 1.6 1 0 0 1 1 1 1 IclR helix-turn-helix domain TrmB PF01978.19 AII58046.1 - 0.00025 20.9 0.0 0.00075 19.3 0.0 1.7 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 AII58046.1 - 0.0009 19.2 0.0 0.0023 17.9 0.0 1.6 2 0 0 2 2 1 1 Crp-like helix-turn-helix domain HTH_34 PF13601.6 AII58046.1 - 0.00091 19.4 0.1 0.0038 17.4 0.1 2.0 2 0 0 2 2 2 1 Winged helix DNA-binding domain MarR PF01047.22 AII58046.1 - 0.0023 17.8 0.1 0.0038 17.1 0.1 1.4 1 0 0 1 1 1 1 MarR family HTH_36 PF13730.6 AII58046.1 - 0.0049 16.8 0.0 0.0093 15.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain TFIIE_alpha PF02002.17 AII58046.1 - 0.0056 16.5 0.1 0.011 15.6 0.0 1.5 2 0 0 2 2 2 1 TFIIE alpha subunit Rrf2 PF02082.20 AII58046.1 - 0.0061 16.9 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator Trp_repressor PF01371.19 AII58046.1 - 0.0087 16.2 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 Trp repressor protein Mga PF05043.13 AII58046.1 - 0.011 16.4 0.2 0.023 15.3 0.1 1.5 2 0 0 2 2 1 0 Mga helix-turn-helix domain DUF4423 PF14394.6 AII58046.1 - 0.013 15.2 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) CtsR_C PF17727.1 AII58046.1 - 0.016 15.3 0.1 0.044 13.9 0.1 1.7 1 0 0 1 1 1 0 CtsR C-terminal dimerization domain RP-C PF03428.13 AII58046.1 - 0.026 14.2 0.1 0.041 13.5 0.1 1.2 1 0 0 1 1 1 0 Replication protein C N-terminal domain Fe_dep_repress PF01325.19 AII58046.1 - 0.031 14.5 0.0 0.059 13.6 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Cdc6_C PF09079.11 AII58046.1 - 0.036 14.0 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain HTH_DeoR PF08220.12 AII58046.1 - 0.046 13.5 0.1 0.087 12.6 0.1 1.4 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_1 PF00126.27 AII58046.1 - 0.051 13.5 0.2 0.19 11.7 0.2 1.9 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_38 PF13936.6 AII58046.1 - 0.053 13.3 0.0 0.49 10.2 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain FaeA PF04703.12 AII58046.1 - 0.053 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 FaeA-like protein HTH_11 PF08279.12 AII58046.1 - 0.11 12.5 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 HTH domain HxlR PF01638.17 AII58046.1 - 0.11 12.3 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 HxlR-like helix-turn-helix ArsP_1 PF03773.13 AII58047.1 - 2e-81 273.4 23.8 2.6e-81 273.0 23.8 1.3 1 0 0 1 1 1 1 Predicted permease PqiA PF04403.13 AII58047.1 - 0.0031 17.3 3.0 0.0031 17.3 3.0 2.7 4 0 0 4 4 4 1 Paraquat-inducible protein A CPP1-like PF11833.8 AII58047.1 - 0.0081 15.8 1.9 0.0081 15.8 1.9 2.1 1 1 1 3 3 3 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Thioredoxin_3 PF13192.6 AII58048.1 - 1.3e-25 89.2 0.7 1.4e-25 89.1 0.7 1.0 1 0 0 1 1 1 1 Thioredoxin domain DivIVA PF05103.13 AII58049.1 - 8.5e-08 32.4 7.9 8.5e-08 32.4 7.9 1.7 2 0 0 2 2 2 1 DivIVA protein Nup54_57_C PF18570.1 AII58049.1 - 0.0038 16.8 2.9 0.011 15.3 2.9 1.9 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain DUF3552 PF12072.8 AII58049.1 - 0.013 15.0 11.0 0.018 14.4 10.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) Mnd1 PF03962.15 AII58049.1 - 0.015 15.5 0.1 0.58 10.5 0.0 2.8 2 0 0 2 2 2 0 Mnd1 HTH domain YodL PF14191.6 AII58049.1 - 0.038 14.9 1.3 0.31 11.9 1.3 2.2 1 1 0 1 1 1 0 YodL-like DUF4230 PF14014.6 AII58049.1 - 0.042 14.1 1.2 0.042 14.1 1.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4230) HALZ PF02183.18 AII58049.1 - 0.063 13.5 0.6 0.063 13.5 0.6 2.8 3 0 0 3 3 2 0 Homeobox associated leucine zipper DUF1492 PF07374.11 AII58049.1 - 0.088 13.0 5.8 0.16 12.1 0.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1492) DUF5339 PF17274.2 AII58049.1 - 0.099 13.5 2.6 0.28 12.1 2.6 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5339) DUF406 PF04175.12 AII58049.1 - 0.16 12.5 6.8 0.098 13.2 3.2 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF406) LPP PF04728.13 AII58049.1 - 0.32 11.4 4.3 2.2 8.7 0.1 2.7 2 1 0 2 2 2 0 Lipoprotein leucine-zipper Spc7 PF08317.11 AII58049.1 - 0.58 9.0 11.3 0.97 8.3 10.9 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein YabA PF06156.13 AII58049.1 - 0.68 10.6 5.3 1.3 9.7 1.0 2.5 1 1 1 2 2 2 0 Initiation control protein YabA FAM76 PF16046.5 AII58049.1 - 0.76 9.1 4.7 1.2 8.4 4.7 1.3 1 0 0 1 1 1 0 FAM76 protein UPF0449 PF15136.6 AII58049.1 - 0.95 10.0 8.7 8.5 6.9 2.4 2.9 1 1 2 3 3 3 0 Uncharacterised protein family UPF0449 DUF2443 PF10398.9 AII58049.1 - 1.5 8.9 6.4 4.9 7.3 0.2 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF2443) CENP-Q PF13094.6 AII58049.1 - 2 8.6 11.7 0.25 11.5 5.2 2.0 1 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit MFS_1 PF07690.16 AII58050.1 - 8.3e-42 143.4 52.7 4.5e-27 94.9 25.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 AII58050.1 - 1.4e-17 63.3 24.5 1.6e-17 63.1 24.5 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1_like PF12832.7 AII58050.1 - 6.8e-16 58.1 31.4 9.7e-16 57.6 31.2 1.4 1 1 0 1 1 1 1 MFS_1 like family LacY_symp PF01306.19 AII58050.1 - 9.8e-07 27.9 25.4 7.1e-06 25.0 9.1 2.1 2 0 0 2 2 2 2 LacY proton/sugar symporter MFS_2 PF13347.6 AII58050.1 - 1.3e-06 27.2 36.3 1.8e-06 26.8 36.3 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein HPP PF04982.13 AII58051.1 - 7.6e-15 55.2 14.7 1.6e-14 54.1 11.9 2.0 2 0 0 2 2 2 1 HPP family SpoVAB PF13782.6 AII58051.1 - 0.034 14.4 7.7 0.82 10.0 0.1 2.3 1 1 1 2 2 2 0 Stage V sporulation protein AB DUF4133 PF13571.6 AII58051.1 - 0.15 12.4 0.4 0.15 12.4 0.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4133) NDUF_C2 PF06374.11 AII58051.1 - 0.16 12.1 0.2 0.49 10.6 0.2 1.9 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) CPP1-like PF11833.8 AII58051.1 - 0.53 9.9 9.1 0.19 11.3 2.9 2.1 1 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like zinc_ribbon_9 PF14369.6 AII58052.1 - 0.0095 16.2 0.4 0.083 13.2 0.0 2.2 2 0 0 2 2 2 1 zinc-ribbon Zn_ribbon_SprT PF17283.2 AII58052.1 - 0.015 15.2 0.0 4.3 7.3 0.0 2.1 2 0 0 2 2 2 0 SprT-like zinc ribbon domain UPF0728 PF15092.6 AII58052.1 - 0.037 13.9 0.0 0.041 13.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0728 Cys_rich_KTR PF14205.6 AII58052.1 - 0.053 13.3 1.0 0.34 10.7 0.0 2.1 1 1 1 2 2 2 0 Cysteine-rich KTR zf-H2C2_2 PF13465.6 AII58052.1 - 0.2 12.1 0.9 2.1 8.9 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger double domain zf_UBZ PF18439.1 AII58052.1 - 0.32 10.6 1.3 4.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_10 PF10058.9 AII58052.1 - 0.44 10.3 4.4 4.5 7.1 0.1 2.4 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein REF PF05755.12 AII58053.1 - 0.014 15.2 0.3 0.016 15.0 0.3 1.0 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) DivIVA PF05103.13 AII58053.1 - 0.043 13.9 4.6 0.048 13.8 4.6 1.1 1 0 0 1 1 1 0 DivIVA protein DUF717 PF05338.12 AII58053.1 - 0.1 12.7 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF717) ACT PF01842.25 AII58054.1 - 6e-13 48.3 0.0 4.8e-09 35.8 0.0 2.2 2 0 0 2 2 2 2 ACT domain ACT_4 PF13291.6 AII58054.1 - 7.4e-06 26.5 0.1 0.0034 17.9 0.1 2.2 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 AII58054.1 - 0.00018 21.2 0.0 0.55 10.1 0.0 2.4 2 0 0 2 2 2 2 ACT domain AMP-binding_C_2 PF14535.6 AII58055.1 - 1e-30 105.9 0.1 3.7e-30 104.1 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 AII58055.1 - 5.5e-18 64.8 0.6 2e-17 62.9 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme GH3 PF03321.13 AII58055.1 - 0.0063 15.4 0.0 0.013 14.4 0.0 1.5 2 0 0 2 2 2 1 GH3 auxin-responsive promoter Cas_Csa4 PF09703.10 AII58055.1 - 0.18 11.1 0.2 1.6 7.9 0.1 2.1 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csa4) PAS_9 PF13426.7 AII58056.1 - 2.9e-64 213.8 5.4 1.3e-11 44.7 0.1 7.3 7 0 0 7 7 7 7 PAS domain PAS_8 PF13188.7 AII58056.1 - 6.1e-48 160.1 2.0 3.9e-09 36.3 0.0 6.6 6 0 0 6 6 6 6 PAS domain PAS_3 PF08447.12 AII58056.1 - 3e-46 155.6 0.0 1.7e-13 50.7 0.1 7.5 7 0 0 7 7 7 6 PAS fold PAS PF00989.25 AII58056.1 - 1.5e-41 140.9 0.1 1.1e-07 31.8 0.0 7.3 7 0 0 7 7 7 6 PAS fold PAS_4 PF08448.10 AII58056.1 - 7.1e-30 103.5 0.0 2.3e-07 31.0 0.0 7.5 7 0 0 7 7 7 4 PAS fold HATPase_c PF02518.26 AII58056.1 - 6.7e-19 68.5 0.1 3.5e-18 66.2 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AII58056.1 - 1.3e-17 64.0 1.0 2.5e-17 63.1 0.2 2.0 2 0 0 2 2 1 1 Response regulator receiver domain HisKA PF00512.25 AII58056.1 - 8.6e-17 60.9 0.0 4.1e-16 58.8 0.0 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain MEKHLA PF08670.11 AII58056.1 - 8.7e-06 25.7 1.3 0.83 9.5 0.1 4.4 4 0 0 4 4 4 2 MEKHLA domain PAS_7 PF12860.7 AII58056.1 - 0.00078 19.6 2.8 4.5 7.5 0.0 5.7 6 0 0 6 6 6 1 PAS fold PEP-utilisers_N PF05524.13 AII58056.1 - 0.075 13.2 1.4 7.1 6.8 0.0 3.5 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal HATPase_c_3 PF13589.6 AII58056.1 - 0.085 12.7 0.0 0.25 11.2 0.0 1.8 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UBA_2 PF08587.11 AII58056.1 - 1.3 9.2 6.0 17 5.7 0.1 4.7 5 0 0 5 5 5 0 Ubiquitin associated domain (UBA) DUF4256 PF14066.6 AII58057.1 - 2e-80 268.5 0.0 2.3e-80 268.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4256) SLBP_RNA_bind PF15247.6 AII58058.1 - 0.023 14.8 0.2 0.025 14.7 0.2 1.1 1 0 0 1 1 1 0 Histone RNA hairpin-binding protein RNA-binding domain Ribonucleas_3_3 PF14622.6 AII58059.1 - 1.2e-28 99.9 0.0 2e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 AII58059.1 - 9.2e-17 61.5 0.1 1.7e-16 60.7 0.1 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 AII58059.1 - 1.5e-16 60.9 0.0 4e-16 59.5 0.0 1.7 2 0 0 2 2 2 1 Ribonuclease III domain Rad52_Rad22 PF04098.15 AII58059.1 - 0.0038 17.2 0.0 0.0058 16.6 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Acylphosphatase PF00708.18 AII58061.1 - 1.4e-25 89.5 0.0 1.5e-25 89.4 0.0 1.0 1 0 0 1 1 1 1 Acylphosphatase DUF362 PF04015.12 AII58062.1 - 4.4e-06 27.1 0.0 7.8e-06 26.3 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF362) Peptidase_M17 PF00883.21 AII58063.1 - 1.3e-115 386.0 0.2 1.6e-115 385.7 0.2 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 AII58063.1 - 5.6e-22 77.9 0.1 3.9e-21 75.2 0.1 2.2 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain AAA_33 PF13671.6 AII58064.1 - 4.2e-21 75.6 0.0 4.9e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain 6PF2K PF01591.18 AII58064.1 - 5.1e-08 32.5 0.1 0.0034 16.7 0.0 2.6 2 1 1 3 3 3 2 6-phosphofructo-2-kinase KTI12 PF08433.10 AII58064.1 - 1e-07 31.7 0.0 1.3e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 AII58064.1 - 7e-06 25.5 0.0 1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 AII58064.1 - 2.7e-05 24.7 0.0 4.8e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 AII58064.1 - 4.2e-05 24.0 0.0 6.8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 AII58064.1 - 6.9e-05 22.8 0.0 9.1e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_5 PF07728.14 AII58064.1 - 0.0019 18.2 0.1 0.0055 16.7 0.0 1.8 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 AII58064.1 - 0.0027 18.0 0.0 0.0042 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AII58064.1 - 0.0068 16.8 0.0 0.016 15.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 AII58064.1 - 0.0088 16.5 0.1 0.016 15.7 0.1 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ADK PF00406.22 AII58064.1 - 0.011 15.8 0.0 0.19 11.8 0.0 2.1 1 1 0 1 1 1 0 Adenylate kinase RNA_helicase PF00910.22 AII58064.1 - 0.012 16.0 0.0 0.022 15.2 0.0 1.5 1 1 0 1 1 1 0 RNA helicase NACHT PF05729.12 AII58064.1 - 0.013 15.4 0.1 1.7 8.6 0.0 2.1 1 1 1 2 2 2 0 NACHT domain Corona_I PF03187.14 AII58064.1 - 0.026 14.2 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 Corona nucleocapsid I protein AAA_24 PF13479.6 AII58064.1 - 0.029 14.1 0.2 0.098 12.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 AII58064.1 - 0.037 14.1 0.0 0.07 13.2 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase CoaE PF01121.20 AII58064.1 - 0.043 13.5 0.1 0.48 10.1 0.0 2.0 1 1 1 2 2 2 0 Dephospho-CoA kinase Mg_chelatase PF01078.21 AII58064.1 - 0.063 12.7 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 AII58064.1 - 0.1 12.6 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AII58064.1 - 0.11 13.0 0.0 0.17 12.4 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 AII58064.1 - 0.16 12.2 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AII58064.1 - 0.21 11.1 0.1 0.48 10.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 AII58064.1 - 0.24 11.1 0.1 0.35 10.5 0.1 1.4 1 1 0 1 1 1 0 AAA domain DegV PF02645.16 AII58065.1 - 2.2e-71 240.5 0.0 2.4e-71 240.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein, DegV family COG1307 Dak1_2 PF13684.6 AII58065.1 - 3.3e-07 29.7 0.1 5.5e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 Dihydroxyacetone kinase family Comm PF15957.5 AII58065.1 - 0.17 12.2 0.0 0.38 11.1 0.0 1.5 1 0 0 1 1 1 0 Commissureless AMP-binding PF00501.28 AII58066.1 - 3.7e-82 276.2 0.0 4.7e-82 275.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AII58066.1 - 5.3e-12 46.6 0.0 1.3e-11 45.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BatD PF13584.6 AII58066.1 - 0.32 9.8 0.0 0.46 9.2 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance PALP PF00291.25 AII58067.1 - 5.4e-43 147.5 0.0 6.4e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Trypsin_2 PF13365.6 AII58068.1 - 2.2e-29 103.3 0.8 3e-29 102.9 0.8 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 AII58068.1 - 2e-11 44.1 0.8 1.1e-10 41.8 0.8 2.0 1 1 0 1 1 1 1 Trypsin Peptidase_S46 PF10459.9 AII58068.1 - 0.012 14.2 2.3 0.8 8.3 0.4 2.1 2 0 0 2 2 2 0 Peptidase S46 UBA_5 PF16577.5 AII58068.1 - 0.062 13.4 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 UBA domain Trypsin_2 PF13365.6 AII58069.1 - 7.1e-28 98.4 2.2 1.1e-27 97.8 2.2 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 AII58069.1 - 1.1e-17 64.1 0.3 3.4e-17 62.5 0.0 1.9 2 0 0 2 2 2 1 PDZ domain Trypsin PF00089.26 AII58069.1 - 5e-13 49.4 0.8 9.2e-13 48.5 0.8 1.4 1 0 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 AII58069.1 - 1.2e-11 44.3 0.1 2.8e-11 43.1 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 AII58069.1 - 1.4e-08 35.0 0.4 4.8e-08 33.2 0.4 2.1 1 1 0 1 1 1 1 PDZ domain Peptidase_S7 PF00949.21 AII58069.1 - 0.022 14.6 0.5 0.06 13.2 0.6 1.7 2 0 0 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S46 PF10459.9 AII58069.1 - 0.079 11.6 3.2 0.42 9.2 0.9 2.0 2 0 0 2 2 2 0 Peptidase S46 Myosin_N PF02736.19 AII58069.1 - 0.98 9.3 4.3 5.2 7.0 0.3 2.5 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain tRNA-synt_1 PF00133.22 AII58070.1 - 4e-171 570.3 0.1 7.1e-171 569.5 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 AII58070.1 - 1.2e-31 109.8 0.1 8.6e-30 103.7 0.0 2.8 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 AII58070.1 - 2.9e-17 62.5 0.1 3.4e-07 29.4 0.0 3.4 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 AII58070.1 - 0.00068 19.1 0.0 0.0031 16.9 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.6 AII58070.1 - 0.0072 15.9 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1f PF01921.18 AII58070.1 - 0.0072 15.3 0.0 0.014 14.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (K) PriA_CRR PF18319.1 AII58070.1 - 0.091 12.8 1.2 13 5.9 0.1 2.6 2 0 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain zf-TFIIB PF13453.6 AII58070.1 - 0.13 11.6 4.9 3.3 7.1 0.1 3.4 3 0 0 3 3 3 0 Transcription factor zinc-finger DZR PF12773.7 AII58070.1 - 0.38 10.8 2.4 45 4.2 0.0 3.4 2 1 0 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 AII58070.1 - 0.96 9.6 4.0 64 3.8 0.0 3.4 3 0 0 3 3 3 0 Zinc ribbon domain DUF2688 PF10892.8 AII58070.1 - 3.9 7.0 4.7 0.72 9.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) Jag_N PF14804.6 AII58071.1 - 8.7e-18 64.4 0.0 1.7e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 Jag N-terminus R3H PF01424.22 AII58071.1 - 2.9e-12 46.4 0.0 5e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 R3H domain KH_4 PF13083.6 AII58071.1 - 1.7e-10 40.6 2.6 6e-10 38.8 0.3 2.9 2 1 1 3 3 3 1 KH domain KH_2 PF07650.17 AII58071.1 - 0.022 14.6 0.0 0.05 13.4 0.0 1.7 1 0 0 1 1 1 0 KH domain DUF348 PF03990.14 AII58071.1 - 1.5 8.6 4.3 0.77 9.6 0.3 2.4 3 0 0 3 3 3 0 G5-linked-Ubiquitin-like domain PQQ_3 PF13570.6 AII58072.1 - 7.1e-50 166.3 26.4 5.4e-11 42.6 0.2 8.2 8 0 0 8 8 8 8 PQQ-like domain PQQ PF01011.21 AII58072.1 - 5.1e-42 139.9 19.5 1.9e-09 37.0 0.2 8.1 8 0 0 8 8 8 6 PQQ enzyme repeat PQQ_2 PF13360.6 AII58072.1 - 2.2e-41 142.0 3.4 3.8e-26 92.1 0.4 2.2 1 1 1 2 2 2 2 PQQ-like domain WD40_like PF17005.5 AII58072.1 - 0.016 14.6 1.6 3.7 6.8 0.4 2.9 2 2 0 2 2 2 0 WD40-like domain LPAM_1 PF08139.12 AII58072.1 - 0.051 14.1 2.3 0.15 12.6 2.3 1.9 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site SH3_19 PF18597.1 AII58072.1 - 0.097 12.5 1.8 8.4 6.3 0.1 3.9 4 0 0 4 4 4 0 Myosin X N-terminal SH3 domain DUF5008 PF16400.5 AII58072.1 - 0.13 12.4 0.6 0.35 11.0 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5008) Ribonuclease_P PF00825.18 AII58073.1 - 4.8e-26 91.0 0.7 5.6e-26 90.8 0.7 1.0 1 0 0 1 1 1 1 Ribonuclease P RNase_E_G PF10150.9 AII58073.1 - 0.0097 15.4 0.1 0.012 15.1 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease E/G family Ribosomal_L34 PF00468.17 AII58074.1 - 1.2e-21 76.4 6.3 1.3e-21 76.3 6.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L34 Ribosomal_S18 PF01084.20 AII58075.1 - 5.4e-24 84.2 1.1 7.8e-24 83.7 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S18 SSB PF00436.25 AII58076.1 - 3.3e-37 126.7 0.1 3.9e-37 126.5 0.1 1.0 1 0 0 1 1 1 1 Single-strand binding protein family tRNA_anti-codon PF01336.25 AII58076.1 - 0.00059 19.8 0.0 0.00093 19.1 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ribosomal_S6 PF01250.17 AII58077.1 - 1.8e-25 89.0 0.2 2.1e-25 88.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 SepF PF04472.12 AII58077.1 - 0.089 13.1 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Cell division protein SepF NYN PF01936.18 AII58078.1 - 6.4e-11 42.9 0.0 9e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 NYN domain RusA PF05866.11 AII58081.1 - 2.9e-27 95.7 0.0 3.4e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Endodeoxyribonuclease RusA YopX PF09643.10 AII58082.1 - 4e-18 65.8 0.2 4.6e-18 65.5 0.2 1.2 1 0 0 1 1 1 1 YopX protein TssN PF17555.2 AII58083.1 - 0.014 14.8 11.6 0.015 14.7 10.6 1.5 1 1 1 2 2 2 0 Type VI secretion system, TssN DUF4271 PF14093.6 AII58083.1 - 0.12 12.2 12.9 0.14 12.0 6.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) MARVEL PF01284.23 AII58083.1 - 0.13 12.3 17.1 1.4 9.0 9.5 2.1 1 1 1 2 2 2 0 Membrane-associating domain YqhR PF11085.8 AII58083.1 - 0.35 10.8 8.6 0.41 10.6 6.5 2.0 1 1 1 2 2 2 0 Conserved membrane protein YqhR HlyIII PF03006.20 AII58083.1 - 0.36 10.5 11.0 0.063 13.0 6.2 1.8 1 1 1 2 2 2 0 Haemolysin-III related 7TMR-DISM_7TM PF07695.11 AII58083.1 - 0.37 10.6 21.1 0.046 13.6 13.8 2.0 1 1 1 2 2 2 0 7TM diverse intracellular signalling Nuc_sug_transp PF04142.15 AII58083.1 - 0.42 9.7 9.1 0.23 10.6 6.9 1.6 2 0 0 2 2 2 0 Nucleotide-sugar transporter Peptidase_U4 PF03419.13 AII58083.1 - 1 8.6 9.9 1.3 8.2 9.9 1.3 1 0 0 1 1 1 0 Sporulation factor SpoIIGA DUF2053 PF09767.9 AII58083.1 - 1.3 9.1 7.7 3.3 7.8 1.2 2.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2053) DUF2070 PF09843.9 AII58083.1 - 1.7 6.8 10.6 2.1 6.5 10.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) YwiC PF14256.6 AII58083.1 - 2 8.7 17.2 4.5 7.6 2.3 2.5 1 1 1 2 2 2 0 YwiC-like protein GNVR PF13807.6 AII58083.1 - 2.5 8.1 0.0 2.5 8.1 0.0 3.4 4 0 0 4 4 4 0 G-rich domain on putative tyrosine kinase BIV_Env PF05858.12 AII58083.1 - 3.6 5.7 7.1 2.4 6.2 3.6 1.8 1 1 1 2 2 2 0 Bovine immunodeficiency virus surface protein (SU) DUF2165 PF09933.9 AII58083.1 - 8.2 6.4 13.0 1.9 8.5 2.5 2.5 2 1 0 2 2 2 0 Predicted small integral membrane protein (DUF2165) HicB PF05534.12 AII58084.1 - 4e-17 61.8 0.0 7.6e-17 60.9 0.0 1.4 1 0 0 1 1 1 1 HicB family HicB_lk_antitox PF15919.5 AII58084.1 - 9.4e-06 25.7 0.0 3.7e-05 23.8 0.0 1.7 1 1 1 2 2 2 1 HicB_like antitoxin of bacterial toxin-antitoxin system Terminase_3C PF17288.2 AII58085.1 - 7.2e-09 36.2 0.1 1.6e-08 35.1 0.1 1.6 1 0 0 1 1 1 1 Terminase RNAseH like domain Terminase_3 PF04466.13 AII58085.1 - 9.5e-05 22.0 0.3 0.00035 20.2 0.3 1.9 1 1 0 1 1 1 1 Phage terminase large subunit HPD PF05044.12 AII58085.1 - 0.093 12.6 0.0 2.9 7.8 0.0 2.2 2 0 0 2 2 2 0 Homeo-prospero domain Peptidase_S78 PF04586.17 AII58086.1 - 5.3e-32 111.2 0.0 7.6e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Caudovirus prohead serine protease HK97-gp10_like PF04883.12 AII58087.1 - 7.8e-09 36.4 0.2 1.5e-08 35.5 0.1 1.5 2 0 0 2 2 2 1 Bacteriophage HK97-gp10, putative tail-component Phage_tail_S PF05069.13 AII58087.1 - 0.0039 17.1 0.0 0.0054 16.6 0.0 1.3 1 0 0 1 1 1 1 Phage virion morphogenesis family Inhibitor_I34 PF10466.9 AII58087.1 - 0.044 14.4 0.8 0.063 13.9 0.1 1.6 2 0 0 2 2 2 0 Saccharopepsin inhibitor I34 NDK PF00334.19 AII58088.1 - 0.027 14.5 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 Nucleoside diphosphate kinase zf-ribbon_3 PF13248.6 AII58088.1 - 0.041 13.3 0.2 0.067 12.6 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-ACC PF17848.1 AII58088.1 - 0.049 13.7 1.0 0.096 12.8 1.0 1.5 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain zf_C2H2_10 PF18414.1 AII58088.1 - 0.081 12.5 0.7 0.14 11.7 0.7 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger OrfB_Zn_ribbon PF07282.11 AII58088.1 - 0.13 12.2 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-C5HC2 PF02928.16 AII58088.1 - 0.13 12.7 0.1 0.19 12.1 0.1 1.3 1 0 0 1 1 1 0 C5HC2 zinc finger Mu-like_Com PF10122.9 AII58088.1 - 0.17 11.3 0.2 0.52 9.8 0.1 1.8 2 0 0 2 2 2 0 Mu-like prophage protein Com Ribonuc_L-PSP PF01042.21 AII58089.1 - 6.4e-32 110.1 0.0 7.7e-32 109.8 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Herpes_IE2_3 PF03361.14 AII58090.1 - 0.016 15.1 10.8 0.27 11.1 4.3 2.7 1 1 0 2 2 2 0 Herpes virus intermediate/early protein 2/3 DUF760 PF05542.11 AII58090.1 - 0.02 15.2 0.1 13 6.2 0.4 3.8 2 2 0 2 2 2 0 Protein of unknown function (DUF760) DUF1192 PF06698.11 AII58090.1 - 0.029 14.4 0.6 0.029 14.4 0.6 4.3 4 1 0 4 4 4 0 Protein of unknown function (DUF1192) ApoLp-III PF07464.11 AII58090.1 - 0.11 12.6 49.3 0.82 9.8 7.9 5.2 1 1 4 5 5 5 0 Apolipophorin-III precursor (apoLp-III) VPS11_C PF12451.8 AII58090.1 - 0.11 12.7 1.7 0.72 10.1 0.1 3.3 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal SCIMP PF15050.6 AII58090.1 - 0.16 12.4 4.5 0.61 10.6 4.5 2.0 1 0 0 1 1 1 0 SCIMP protein Tubulin PF00091.25 AII58091.1 - 3.4e-27 95.9 0.0 5.4e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 AII58091.1 - 0.069 12.3 0.3 1.1 8.3 0.0 2.2 1 1 1 2 2 2 0 Tubulin like Gly_kinase PF02595.15 AII58091.1 - 8.8 5.2 8.1 5.5 5.9 0.1 2.8 2 1 1 3 3 3 0 Glycerate kinase family SMC_N PF02463.19 AII58092.1 - 1.1e-12 47.9 0.0 1.8e-12 47.2 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AII58092.1 - 1.5e-06 27.8 0.0 3.3e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 AII58092.1 - 1.6e-06 28.8 20.7 2.8e-05 24.7 17.6 3.4 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 AII58092.1 - 2.3e-06 27.6 0.0 1.3e-05 25.1 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain DUF2333 PF10095.9 AII58092.1 - 0.00087 18.4 0.1 0.0022 17.1 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2333) NPV_P10 PF05531.12 AII58092.1 - 0.0026 18.2 0.3 4.4 7.8 0.0 3.7 2 1 1 3 3 3 1 Nucleopolyhedrovirus P10 protein AAA_22 PF13401.6 AII58092.1 - 0.003 17.8 0.1 0.045 14.0 0.0 2.7 3 0 0 3 3 3 1 AAA domain Baculo_PEP_C PF04513.12 AII58092.1 - 0.0036 17.3 3.3 0.73 9.9 0.2 3.3 2 1 1 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_27 PF13514.6 AII58092.1 - 0.011 15.4 0.7 0.044 13.4 0.0 2.5 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 AII58092.1 - 0.031 14.8 1.6 0.1 13.1 1.1 2.4 1 1 0 1 1 1 0 ABC transporter Plasmid_RAQPRD PF09686.10 AII58092.1 - 0.06 13.6 6.2 0.097 12.9 2.5 3.0 3 0 0 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) AAA_21 PF13304.6 AII58092.1 - 0.11 12.3 5.8 0.12 12.2 0.3 3.3 2 2 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Big_1 PF02369.16 AII58092.1 - 0.12 12.4 0.0 0.37 10.8 0.1 1.8 2 0 0 2 2 1 0 Bacterial Ig-like domain (group 1) Laminin_II PF06009.12 AII58092.1 - 0.13 12.3 3.5 2.2 8.3 0.1 2.9 2 1 0 2 2 2 0 Laminin Domain II AAA_16 PF13191.6 AII58092.1 - 0.36 11.2 2.6 1.5 9.1 1.3 2.7 2 1 0 2 2 2 0 AAA ATPase domain DASH_Dad2 PF08654.10 AII58092.1 - 0.48 10.9 0.1 0.48 10.9 0.1 3.6 4 0 0 4 4 3 0 DASH complex subunit Dad2 Syntaxin-6_N PF09177.11 AII58092.1 - 1.8 9.1 8.8 5.3 7.7 0.2 3.8 3 1 1 4 4 3 0 Syntaxin 6, N-terminal FUSC PF04632.12 AII58092.1 - 3.1 6.2 4.3 1.3 7.5 2.0 1.5 2 0 0 2 2 2 0 Fusaric acid resistance protein family FlxA PF14282.6 AII58092.1 - 5.9 6.9 8.2 4.6 7.3 2.4 2.8 2 1 0 2 2 2 0 FlxA-like protein EamA PF00892.20 AII58093.1 - 2.3e-51 173.6 40.3 3.7e-26 91.9 15.2 2.0 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 AII58093.1 - 1e-07 31.6 9.3 2.4e-07 30.4 9.3 1.6 1 1 0 1 1 1 1 Triose-phosphate Transporter family PUNUT PF16913.5 AII58093.1 - 0.00011 21.6 3.1 0.00011 21.6 3.1 2.0 1 1 1 2 2 2 1 Purine nucleobase transmembrane transport DUF2516 PF10724.9 AII58093.1 - 0.021 15.1 0.5 0.021 15.1 0.5 3.3 2 2 2 4 4 4 0 Protein of unknown function (DUF2516) UAA PF08449.11 AII58093.1 - 0.07 12.3 7.7 0.017 14.3 1.2 2.3 2 1 0 2 2 2 0 UAA transporter family DUF4122 PF13498.6 AII58093.1 - 0.23 11.2 0.1 0.34 10.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4122) DUF2680 PF10925.8 AII58094.1 - 0.00081 19.3 0.8 0.0013 18.7 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2680) SurA_N_2 PF13623.6 AII58094.1 - 0.033 14.1 3.2 0.051 13.5 3.2 1.3 1 0 0 1 1 1 0 SurA N-terminal domain LysM PF01476.20 AII58094.1 - 0.12 12.5 0.3 0.55 10.3 0.1 2.0 2 0 0 2 2 2 0 LysM domain HTH_35 PF13693.6 AII58094.1 - 0.12 12.4 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Response_reg PF00072.24 AII58095.1 - 1.9e-31 108.5 0.2 3.2e-31 107.8 0.2 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AII58095.1 - 2.4e-22 78.8 0.0 4.9e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal MarR_2 PF12802.7 AII58095.1 - 0.0071 16.2 0.1 0.064 13.2 0.0 2.2 2 0 0 2 2 2 1 MarR family HATPase_c PF02518.26 AII58096.1 - 4.5e-29 101.2 0.0 2.6e-28 98.7 0.0 2.2 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 AII58096.1 - 2.7e-16 59.7 0.2 6e-16 58.6 0.2 1.7 1 0 0 1 1 1 1 HAMP domain HisKA PF00512.25 AII58096.1 - 8.5e-15 54.6 2.0 4.7e-14 52.2 0.4 2.7 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 AII58096.1 - 0.0012 18.8 0.0 0.0031 17.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 AII58096.1 - 0.0041 17.0 0.1 0.026 14.4 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AII58096.1 - 0.011 15.7 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 GHKL domain betaPIX_CC PF16523.5 AII58096.1 - 0.084 12.7 0.2 0.18 11.6 0.2 1.5 1 0 0 1 1 1 0 betaPIX coiled coil Secretin_N PF03958.17 AII58096.1 - 0.34 11.4 3.3 5.9 7.4 0.6 2.9 2 1 0 2 2 2 0 Bacterial type II/III secretion system short domain ABC_tran PF00005.27 AII58097.1 - 2.3e-30 105.9 0.0 3.1e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 AII58097.1 - 3.9e-17 62.5 0.4 5.2e-16 58.9 0.1 2.3 2 0 0 2 2 2 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 AII58097.1 - 3.5e-06 27.1 0.4 0.0039 17.0 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AII58097.1 - 0.0013 18.2 0.0 0.0026 17.2 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 AII58097.1 - 0.0088 16.3 0.5 0.06 13.6 0.5 2.0 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AII58097.1 - 0.017 14.9 0.1 0.029 14.1 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 AII58097.1 - 0.018 15.4 0.1 0.024 15.0 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 AII58097.1 - 0.023 13.9 0.0 0.026 13.7 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit Mg_chelatase PF01078.21 AII58097.1 - 0.082 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATP-synt_ab PF00006.25 AII58097.1 - 0.094 12.4 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 AII58097.1 - 0.1 11.8 0.2 0.23 10.6 0.2 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.29 AII58097.1 - 0.13 12.7 0.0 0.41 11.1 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.6 AII58097.1 - 0.13 10.8 0.2 2.9 6.4 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 AII58097.1 - 0.21 11.1 0.1 0.34 10.4 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 AII58098.1 - 2.2e-27 96.3 0.0 3e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 AII58098.1 - 4.4e-20 72.0 0.1 8.1e-20 71.1 0.1 1.5 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region SMC_N PF02463.19 AII58098.1 - 2.3e-07 30.5 0.0 4.1e-07 29.7 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AII58098.1 - 7.2e-05 22.7 0.2 0.00021 21.2 0.1 1.7 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AII58098.1 - 0.032 14.6 0.0 0.049 14.0 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 AII58098.1 - 0.034 14.4 0.6 0.15 12.4 0.6 2.0 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 AII58098.1 - 0.053 13.9 0.1 1.1 9.7 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 AII58098.1 - 0.11 12.3 0.3 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein BPD_transp_1 PF00528.22 AII58099.1 - 2e-31 109.1 15.4 2e-31 109.1 15.4 1.6 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 AII58099.1 - 1.9e-14 53.3 0.9 1.9e-14 53.3 0.9 3.4 3 0 0 3 3 3 1 N-terminal TM domain of oligopeptide transport permease C BPD_transp_1 PF00528.22 AII58100.1 - 4.4e-42 143.9 17.1 4.4e-42 143.9 17.1 1.7 3 0 0 3 3 3 1 Binding-protein-dependent transport system inner membrane component SBP_bac_5 PF00496.22 AII58101.1 - 1.6e-83 280.7 10.9 2.2e-83 280.3 10.9 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Beta-Casp PF10996.8 AII58102.1 - 2.7e-28 98.5 0.0 5.9e-28 97.4 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 AII58102.1 - 3.1e-14 52.6 0.0 7.3e-14 51.4 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_6 PF16661.5 AII58102.1 - 9.3e-14 51.3 0.0 1.4e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 AII58102.1 - 3e-10 40.4 0.0 1.5e-09 38.1 0.0 2.2 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 AII58102.1 - 1.1e-09 38.2 0.1 5.2e-09 35.9 0.1 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 AII58102.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Response_reg PF00072.24 AII58103.1 - 5.4e-26 90.9 0.1 8.1e-26 90.4 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AII58103.1 - 2.6e-22 78.1 0.1 7.2e-22 76.7 0.1 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family HTH_23 PF13384.6 AII58103.1 - 6.1e-06 25.9 0.0 1.5e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 AII58103.1 - 3.2e-05 23.5 0.1 8.4e-05 22.2 0.1 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AII58103.1 - 0.0019 17.7 1.6 0.002 17.6 0.1 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_28 PF13518.6 AII58103.1 - 0.0024 18.0 0.0 0.0055 16.8 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_ECF PF07638.11 AII58103.1 - 0.0098 15.8 0.0 0.024 14.5 0.0 1.6 1 1 0 1 1 1 1 ECF sigma factor HTH_38 PF13936.6 AII58103.1 - 0.011 15.4 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_40 PF14493.6 AII58103.1 - 0.017 15.6 0.0 0.1 13.1 0.0 2.1 1 1 1 2 2 2 0 Helix-turn-helix domain LSDAT_euk PF18139.1 AII58103.1 - 0.021 14.2 0.1 0.028 13.8 0.1 1.2 1 0 0 1 1 1 0 SLOG in TRPM Terminase_5 PF06056.12 AII58103.1 - 0.026 14.4 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_24 PF13412.6 AII58103.1 - 0.033 13.8 0.0 0.059 12.9 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_7 PF02796.15 AII58103.1 - 0.12 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase TadZ_N PF16968.5 AII58103.1 - 0.14 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Pilus assembly protein TadZ N-terminal PAS_9 PF13426.7 AII58104.1 - 2.9e-50 168.9 0.0 1.2e-11 44.8 0.0 6.4 6 0 0 6 6 6 5 PAS domain PAS_4 PF08448.10 AII58104.1 - 3.3e-48 162.5 0.0 2.2e-11 44.0 0.0 6.3 6 0 0 6 6 6 6 PAS fold PAS PF00989.25 AII58104.1 - 9.1e-43 144.8 0.0 1.1e-11 44.7 0.0 6.9 6 0 0 6 6 6 6 PAS fold PAS_3 PF08447.12 AII58104.1 - 2e-35 120.9 0.0 8.9e-16 58.0 0.0 5.1 5 0 0 5 5 5 4 PAS fold PAS_8 PF13188.7 AII58104.1 - 3.7e-20 71.5 0.0 0.00044 20.2 0.0 5.7 5 0 0 5 5 5 3 PAS domain HisKA_3 PF07730.13 AII58104.1 - 6e-15 55.5 1.0 6e-15 55.5 1.0 2.5 2 0 0 2 2 2 1 Histidine kinase GAF_2 PF13185.6 AII58104.1 - 3e-11 43.8 0.0 6.6e-09 36.2 0.0 3.1 3 0 0 3 3 3 1 GAF domain HATPase_c PF02518.26 AII58104.1 - 3.4e-09 37.2 0.1 1.7e-08 34.9 0.0 2.3 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_10 PF13596.6 AII58104.1 - 4.2e-06 27.3 0.0 0.0012 19.4 0.0 3.4 3 0 0 3 3 3 1 PAS domain HATPase_c_2 PF13581.6 AII58104.1 - 1.5e-05 25.0 0.0 6.3e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain PAS_7 PF12860.7 AII58104.1 - 6.2e-05 23.1 0.1 0.16 12.1 0.0 5.5 6 0 0 6 6 6 1 PAS fold GAF PF01590.26 AII58104.1 - 0.00093 19.8 0.0 0.044 14.4 0.0 3.3 3 0 0 3 3 3 1 GAF domain tRNA_U5-meth_tr PF05958.11 AII58105.1 - 4.2e-18 65.5 0.1 3.6e-14 52.5 0.1 3.0 2 1 0 2 2 2 2 tRNA (Uracil-5-)-methyltransferase MTS PF05175.14 AII58105.1 - 0.00086 18.9 0.1 0.0014 18.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 AII58105.1 - 0.0009 19.0 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein RrnaAD PF00398.20 AII58105.1 - 0.0017 17.5 0.0 0.0028 16.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Cons_hypoth95 PF03602.15 AII58105.1 - 0.0023 17.6 0.0 0.0041 16.8 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 AII58105.1 - 0.0077 16.9 0.0 0.14 12.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Pro_CA PF00484.19 AII58106.1 - 7.3e-05 23.1 0.0 8.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Carbonic anhydrase Maf PF02545.14 AII58107.1 - 1.6e-47 161.5 0.0 1.8e-47 161.3 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein tRNA_bind PF01588.20 AII58107.1 - 0.16 12.1 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative tRNA binding domain DUF3795 PF12675.7 AII58108.1 - 1.8e-06 28.3 28.6 4.8e-06 26.9 20.0 3.1 2 1 0 2 2 2 1 Protein of unknown function (DUF3795) DZR PF12773.7 AII58108.1 - 4.5 7.4 28.2 1.7 8.8 2.9 3.0 2 1 1 3 3 3 0 Double zinc ribbon NAD_synthase PF02540.17 AII58109.1 - 8.5e-77 257.5 0.0 1.2e-76 257.0 0.0 1.2 1 0 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.22 AII58109.1 - 6e-31 107.7 0.0 8.5e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase tRNA_Me_trans PF03054.16 AII58109.1 - 0.0036 16.1 0.0 0.0052 15.6 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.21 AII58109.1 - 0.0081 15.9 1.2 0.013 15.2 1.2 1.2 1 0 0 1 1 1 1 Asparagine synthase UBA PF00627.31 AII58109.1 - 0.079 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain Gln-synt_C PF00120.24 AII58110.1 - 4.3e-128 427.1 0.0 5.1e-128 426.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 AII58110.1 - 1.4e-28 98.4 0.0 4.1e-28 96.9 0.0 1.8 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Gln-synt_N_2 PF16952.5 AII58110.1 - 0.009 15.8 0.0 0.031 14.1 0.0 1.9 1 1 0 1 1 1 1 Glutamine synthetase N-terminal domain P-II PF00543.22 AII58111.1 - 6.2e-37 126.3 0.2 6.9e-37 126.1 0.2 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II Ammonium_transp PF00909.21 AII58112.1 - 4.7e-128 427.3 37.9 5.3e-128 427.1 37.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Trans_reg_C PF00486.28 AII58113.1 - 3.4e-27 94.3 0.1 5.6e-27 93.6 0.1 1.3 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal GXGXG PF01493.19 AII58114.1 - 6.9e-36 123.6 7.8 8.9e-36 123.3 7.8 1.1 1 0 0 1 1 1 1 GXGXG motif Glu_synthase PF01645.17 AII58115.1 - 6e-132 440.2 0.2 9.6e-132 439.6 0.2 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 AII58115.1 - 6.6e-15 55.3 0.1 1.2e-07 31.5 0.1 2.3 2 0 0 2 2 2 2 Glutamate synthase central domain FMN_dh PF01070.18 AII58115.1 - 9.5e-09 34.7 9.1 9.2e-08 31.5 4.1 3.1 3 1 0 3 3 3 1 FMN-dependent dehydrogenase Fer4_9 PF13187.6 AII58115.1 - 2.6e-07 30.7 11.6 2.6e-07 30.7 11.6 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 AII58115.1 - 3.4e-07 30.3 11.2 3.4e-07 30.3 11.2 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4 PF00037.27 AII58115.1 - 2.8e-06 26.9 20.0 1.5e-05 24.6 1.6 3.3 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_7 PF12838.7 AII58115.1 - 7e-06 26.5 12.7 7e-06 26.5 12.7 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain IMPDH PF00478.25 AII58115.1 - 1e-05 24.8 7.1 1.7e-05 24.0 5.8 1.9 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Fer4_10 PF13237.6 AII58115.1 - 1.5e-05 25.0 23.3 0.00012 22.1 12.8 2.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AII58115.1 - 0.00011 23.1 0.1 0.00011 23.1 0.1 3.2 3 0 0 3 3 3 1 4Fe-4S double cluster binding domain NMO PF03060.15 AII58115.1 - 0.00074 19.0 4.6 0.00087 18.8 2.6 2.0 3 0 0 3 3 3 1 Nitronate monooxygenase Fer4_6 PF12837.7 AII58115.1 - 0.0013 18.7 1.8 0.0013 18.7 1.8 2.9 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 AII58115.1 - 0.0016 18.4 1.4 0.0016 18.4 1.4 3.4 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 AII58115.1 - 0.0029 18.1 16.8 0.19 12.3 1.3 3.4 2 1 1 3 3 3 1 4Fe-4S dicluster domain His_biosynth PF00977.21 AII58115.1 - 0.0036 16.8 0.9 0.01 15.3 0.1 2.0 2 0 0 2 2 2 1 Histidine biosynthesis protein Fer4_4 PF12800.7 AII58115.1 - 0.012 16.0 3.7 0.012 16.0 3.7 3.3 3 0 0 3 3 3 0 4Fe-4S binding domain DHO_dh PF01180.21 AII58115.1 - 0.072 12.3 1.1 0.18 10.9 1.1 1.7 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase Cytochrome_CBB3 PF13442.6 AII58115.1 - 0.13 12.6 3.7 1.2 9.5 0.1 3.1 3 0 0 3 3 3 0 Cytochrome C oxidase, cbb3-type, subunit III Fer4_8 PF13183.6 AII58115.1 - 0.74 10.3 19.9 0.83 10.2 13.6 2.9 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 AII58115.1 - 1.1 9.9 14.6 3.4 8.3 4.3 2.7 1 1 1 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 AII58115.1 - 1.7 8.8 13.6 0.13 12.5 1.8 2.6 1 1 1 2 2 2 0 4Fe-4S dicluster domain His_biosynth PF00977.21 AII58116.1 - 1.5e-86 289.6 0.1 1.7e-86 289.4 0.1 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.15 AII58116.1 - 2e-07 30.7 0.2 0.0023 17.4 0.0 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase ThiG PF05690.14 AII58116.1 - 7.8e-07 28.7 0.1 0.014 14.7 0.0 2.1 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 AII58116.1 - 3.5e-06 26.3 0.0 0.017 14.2 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) G3P_antiterm PF04309.12 AII58116.1 - 7.4e-06 25.5 0.1 0.02 14.3 0.1 2.2 2 0 0 2 2 2 2 Glycerol-3-phosphate responsive antiterminator TMP-TENI PF02581.17 AII58116.1 - 6.4e-05 22.4 0.1 0.22 10.9 0.0 2.3 2 0 0 2 2 2 2 Thiamine monophosphate synthase SBP_bac_3 PF00497.20 AII58116.1 - 0.00024 20.6 0.0 0.00042 19.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DHO_dh PF01180.21 AII58116.1 - 0.00032 20.0 0.0 0.28 10.3 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase IMPDH PF00478.25 AII58116.1 - 0.00082 18.5 0.9 0.49 9.3 0.2 2.2 1 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 AII58116.1 - 0.073 12.1 0.7 8.8 5.2 0.0 2.5 1 1 2 3 3 3 0 FMN-dependent dehydrogenase GATase_2 PF00310.21 AII58117.1 - 7e-10 38.2 0.0 3.9e-08 32.4 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 AII58117.1 - 7.8e-07 29.4 0.0 6.5e-06 26.4 0.0 2.3 2 1 1 3 3 3 1 Glutamine amidotransferase domain GATase_7 PF13537.6 AII58117.1 - 1.5e-06 28.1 0.0 0.0035 17.3 0.0 2.6 3 0 0 3 3 3 2 Glutamine amidotransferase domain Pyr_redox_2 PF07992.14 AII58118.1 - 2.4e-51 174.7 3.0 3.2e-51 174.3 3.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 AII58118.1 - 5.6e-14 52.5 8.9 5e-13 49.4 2.2 3.4 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 AII58118.1 - 3.6e-05 22.6 3.5 0.36 9.5 1.3 3.3 2 1 1 3 3 3 2 HI0933-like protein Pyr_redox_3 PF13738.6 AII58118.1 - 6.7e-05 22.3 2.9 6.7e-05 22.3 2.9 3.6 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rubredoxin_C PF18267.1 AII58118.1 - 6.9e-05 22.7 0.0 0.00023 21.0 0.0 2.0 1 0 0 1 1 1 1 Rubredoxin NAD+ reductase C-terminal domain NAD_binding_8 PF13450.6 AII58118.1 - 0.00018 21.6 0.4 0.00018 21.6 0.4 3.5 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain DUF1188 PF06690.11 AII58118.1 - 0.00034 20.3 2.1 0.00061 19.4 2.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) AlaDh_PNT_C PF01262.21 AII58118.1 - 0.00065 19.1 0.9 0.0013 18.1 0.9 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain CBS PF00571.28 AII58118.1 - 0.0015 18.9 0.0 0.0072 16.7 0.0 2.2 1 0 0 1 1 1 1 CBS domain FAD_binding_3 PF01494.19 AII58118.1 - 0.0023 17.2 0.4 0.0041 16.4 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 AII58118.1 - 0.021 13.9 5.7 0.62 9.1 1.7 2.6 3 0 0 3 3 3 0 FAD binding domain GIDA PF01134.22 AII58118.1 - 0.032 13.3 6.7 0.075 12.1 1.2 2.7 2 1 1 3 3 3 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 AII58118.1 - 0.034 14.0 0.7 0.054 13.4 0.7 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Orn_DAP_Arg_deC PF00278.22 AII58118.1 - 0.036 14.3 0.0 0.059 13.6 0.0 1.5 1 1 0 1 1 1 0 Pyridoxal-dependent decarboxylase, C-terminal sheet domain DAO PF01266.24 AII58118.1 - 0.1 12.2 5.9 0.1 12.1 2.5 2.2 1 1 1 2 2 2 0 FAD dependent oxidoreductase TrkA_N PF02254.18 AII58118.1 - 0.61 10.4 3.1 1.3 9.3 0.2 2.7 3 0 0 3 3 3 0 TrkA-N domain Lycopene_cycl PF05834.12 AII58118.1 - 1.1 8.2 2.7 5.5 5.9 0.7 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein GATase PF00117.28 AII58119.1 - 2.5e-19 69.8 0.0 2.8e-19 69.6 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 AII58119.1 - 5.9e-09 35.8 0.0 8.2e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 AII58119.1 - 5.6e-07 29.6 0.0 7.3e-05 22.7 0.0 2.0 2 0 0 2 2 2 2 SNO glutamine amidotransferase family Peptidase_C26 PF07722.13 AII58119.1 - 0.00028 20.7 0.0 0.012 15.4 0.0 2.1 2 0 0 2 2 2 1 Peptidase C26 DJ-1_PfpI PF01965.24 AII58119.1 - 0.0033 17.3 0.1 0.0044 16.8 0.1 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_5 PF13507.6 AII58119.1 - 0.066 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Asparaginase_C PF17763.1 AII58119.1 - 0.15 12.3 0.0 0.36 11.1 0.0 1.5 1 1 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain Fer4_11 PF13247.6 AII58120.1 - 1.6e-15 57.0 8.5 1.6e-15 57.0 8.5 1.7 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AII58120.1 - 3.3e-11 43.6 23.9 6e-05 23.6 7.7 3.2 3 0 0 3 3 3 3 4Fe-4S dicluster domain Fer4 PF00037.27 AII58120.1 - 1.5e-10 40.5 31.2 6.3e-07 28.9 2.5 4.7 5 0 0 5 5 5 3 4Fe-4S binding domain Fer4_10 PF13237.6 AII58120.1 - 1.1e-09 38.2 26.6 4.6e-07 29.8 10.3 2.4 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AII58120.1 - 1.6e-09 37.8 25.8 1.5e-05 25.1 9.9 3.1 1 1 3 4 4 4 4 4Fe-4S dicluster domain Fer4_2 PF12797.7 AII58120.1 - 3.2e-07 30.0 30.0 0.0002 21.3 1.1 4.1 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_21 PF14697.6 AII58120.1 - 4.8e-07 29.8 26.3 0.0005 20.1 8.9 2.7 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AII58120.1 - 5e-07 29.5 30.8 0.00032 20.7 2.3 4.3 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_4 PF12800.7 AII58120.1 - 0.00014 22.1 28.1 0.022 15.2 1.4 4.3 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_15 PF13459.6 AII58120.1 - 0.015 16.0 14.6 0.32 11.8 0.6 3.1 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_16 PF13484.6 AII58120.1 - 0.016 16.1 28.7 0.18 12.7 5.7 4.3 2 2 2 4 4 4 0 4Fe-4S double cluster binding domain Fer4_3 PF12798.7 AII58120.1 - 0.017 16.0 39.6 0.52 11.4 3.5 4.2 4 0 0 4 4 4 0 4Fe-4S binding domain Fer4_8 PF13183.6 AII58120.1 - 0.032 14.7 27.2 0.24 11.9 1.5 3.3 2 2 1 3 3 3 0 4Fe-4S dicluster domain Fe_dep_repr_C PF02742.15 AII58120.1 - 0.049 13.7 0.0 0.092 12.8 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain Fer4_17 PF13534.6 AII58120.1 - 0.13 12.8 0.4 0.13 12.8 0.4 4.2 2 1 2 4 4 4 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 AII58120.1 - 0.19 12.3 16.6 1.5 9.4 0.3 3.2 2 1 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Mntp PF02659.15 AII58121.1 - 4.5e-42 143.4 15.8 4.5e-42 143.4 15.8 2.0 1 1 1 2 2 2 2 Putative manganese efflux pump PALP PF00291.25 AII58122.1 - 2.5e-72 243.8 0.2 2.8e-72 243.6 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Pribosyltran PF00156.27 AII58122.1 - 0.097 12.2 0.0 0.36 10.3 0.0 1.8 2 0 0 2 2 2 0 Phosphoribosyl transferase domain Radical_SAM PF04055.21 AII58124.1 - 4.2e-14 53.3 0.1 1.3e-13 51.6 0.1 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 AII58124.1 - 0.0034 17.6 0.6 0.0078 16.5 0.6 1.6 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AII58124.1 - 0.53 10.4 4.9 7.2 6.8 4.9 2.4 1 1 0 1 1 1 0 4Fe-4S single cluster domain CobD_Cbib PF03186.13 AII58125.1 - 7.1e-76 255.0 0.1 8.6e-76 254.8 0.1 1.1 1 0 0 1 1 1 1 CobD/Cbib protein Sigma_reg_N PF13800.6 AII58125.1 - 0.24 11.7 3.0 3.5 8.0 0.0 2.6 2 0 0 2 2 2 0 Sigma factor regulator N-terminal CobA_CobO_BtuR PF02572.15 AII58126.1 - 1.6e-56 191.3 0.0 1.7e-56 191.1 0.0 1.0 1 0 0 1 1 1 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP ArsA_ATPase PF02374.15 AII58126.1 - 0.05 12.8 0.4 0.16 11.1 0.0 1.8 2 0 0 2 2 2 0 Anion-transporting ATPase CN_hydrolase PF00795.22 AII58127.1 - 1.5e-22 80.2 0.0 1.8e-22 80.0 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Polysacc_deac_1 PF01522.21 AII58128.1 - 7.4e-30 103.4 0.0 1.2e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glycos_transf_2 PF00535.26 AII58128.1 - 9.8e-27 93.8 0.0 3e-26 92.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 AII58128.1 - 1.3e-14 54.7 0.0 2.3e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 AII58128.1 - 3.8e-09 36.3 0.0 6.8e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 AII58128.1 - 9e-08 32.3 1.3 2e-07 31.1 1.3 1.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_4 PF13704.6 AII58128.1 - 6.1e-06 26.7 0.0 1.6e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 AII58128.1 - 2.4e-05 23.9 0.1 7.6e-05 22.3 0.1 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 zf-C2HC5 PF06221.13 AII58128.1 - 0.038 14.0 0.9 0.11 12.5 0.9 1.7 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type PrsW-protease PF13367.6 AII58130.1 - 9.1e-26 90.5 21.6 1.7e-25 89.6 21.6 1.5 1 1 0 1 1 1 1 PrsW family intramembrane metalloprotease Response_reg PF00072.24 AII58132.1 - 3.4e-25 88.4 0.0 5.3e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 AII58132.1 - 8.4e-17 60.5 0.4 2.9e-16 58.7 0.1 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family HTH_23 PF13384.6 AII58132.1 - 0.024 14.4 0.0 0.23 11.3 0.0 2.4 2 1 1 3 3 3 0 Homeodomain-like domain Sigma70_r4_2 PF08281.12 AII58132.1 - 0.034 13.8 0.0 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 DUF2201 PF09967.9 AII58132.1 - 0.039 14.1 0.0 0.076 13.2 0.0 1.5 1 0 0 1 1 1 0 VWA-like domain (DUF2201) HTH_38 PF13936.6 AII58132.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain ATP-grasp_5 PF13549.6 AII58133.1 - 3.5e-78 262.1 0.1 5.4e-78 261.5 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 AII58133.1 - 4.2e-52 175.6 1.0 7.6e-52 174.8 0.5 1.7 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 AII58133.1 - 8.4e-25 87.5 0.1 2.4e-24 86.0 0.1 1.9 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 AII58133.1 - 2.4e-10 40.9 0.5 1.5e-09 38.4 0.1 2.6 2 0 0 2 2 2 1 CoA binding domain Acetyltransf_1 PF00583.25 AII58133.1 - 3.1e-06 27.4 0.1 6.6e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 AII58133.1 - 7.3e-05 22.9 0.1 0.00061 20.0 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 AII58133.1 - 0.016 15.1 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ETF PF01012.21 AII58133.1 - 0.036 14.0 0.2 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 Electron transfer flavoprotein domain NAD_Gly3P_dh_N PF01210.23 AII58133.1 - 0.077 13.0 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FUR PF01475.19 AII58134.1 - 4.9e-29 100.9 1.3 5.9e-29 100.6 1.3 1.1 1 0 0 1 1 1 1 Ferric uptake regulator family PadR PF03551.14 AII58134.1 - 0.0017 18.3 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family TrmB PF01978.19 AII58134.1 - 0.0099 15.7 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Penicillinase_R PF03965.16 AII58134.1 - 0.013 15.8 0.0 0.019 15.3 0.0 1.3 1 0 0 1 1 1 0 Penicillinase repressor HTH_11 PF08279.12 AII58134.1 - 0.018 15.0 0.2 0.054 13.5 0.1 2.0 2 1 0 2 2 2 0 HTH domain zf_UBZ PF18439.1 AII58134.1 - 0.1 12.2 0.7 0.1 12.2 0.7 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger HTH_32 PF13565.6 AII58134.1 - 0.15 12.7 0.0 0.27 11.9 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Abhydrolase_6 PF12697.7 AII58135.1 - 2.9e-12 47.7 0.0 3.6e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 AII58135.1 - 8.9e-09 35.4 0.4 1.1e-07 31.8 0.4 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 AII58135.1 - 0.0012 18.1 0.0 0.0047 16.2 0.0 2.1 2 1 0 2 2 2 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 AII58135.1 - 0.016 14.7 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF3530 PF12048.8 AII58135.1 - 0.031 13.7 0.0 0.052 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Abhydrolase_2 PF02230.16 AII58135.1 - 0.06 13.1 0.1 0.27 11.0 0.1 2.0 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase BAAT_C PF08840.11 AII58135.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Ser_hydrolase PF06821.13 AII58135.1 - 0.12 12.3 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase DUF1749 PF08538.10 AII58135.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) PGAP1 PF07819.13 AII58135.1 - 0.2 11.4 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein MarR_2 PF12802.7 AII58136.1 - 1.7e-12 47.0 0.0 2.7e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 MarR family MarR PF01047.22 AII58136.1 - 1.7e-11 43.8 0.0 2.9e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 MarR family B-block_TFIIIC PF04182.12 AII58136.1 - 1.8e-05 24.8 0.0 4.3e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 B-block binding subunit of TFIIIC HTH_27 PF13463.6 AII58136.1 - 3.7e-05 24.1 0.0 6.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_24 PF13412.6 AII58136.1 - 3.7e-05 23.2 0.0 6.8e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding DUF4364 PF14277.6 AII58136.1 - 0.0037 17.0 0.3 0.0055 16.5 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) HTH_IclR PF09339.10 AII58136.1 - 0.0096 15.7 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_Crp_2 PF13545.6 AII58136.1 - 0.017 15.1 0.1 0.041 13.9 0.1 1.8 2 1 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_34 PF13601.6 AII58136.1 - 0.029 14.5 0.0 0.067 13.4 0.0 1.6 1 1 1 2 2 2 0 Winged helix DNA-binding domain Dynamin_N PF00350.23 AII58136.1 - 0.096 12.7 0.6 0.17 12.0 0.4 1.5 2 0 0 2 2 2 0 Dynamin family ABC_tran PF00005.27 AII58137.1 - 6.7e-32 110.9 0.1 1.3e-31 109.9 0.1 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 AII58137.1 - 8.5e-30 104.3 22.2 8.5e-30 104.3 22.2 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 AII58137.1 - 1.9e-06 27.5 4.2 0.00017 21.1 0.3 2.4 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 AII58137.1 - 0.002 18.0 0.5 0.023 14.6 0.0 2.7 3 0 0 3 3 3 1 RsgA GTPase AAA_29 PF13555.6 AII58137.1 - 0.0037 17.0 0.4 0.0089 15.7 0.4 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF87 PF01935.17 AII58137.1 - 0.007 16.5 0.2 0.024 14.7 0.2 1.9 1 0 0 1 1 1 1 Helicase HerA, central domain DUF3584 PF12128.8 AII58137.1 - 0.01 13.4 0.0 0.016 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Zeta_toxin PF06414.12 AII58137.1 - 0.011 15.0 0.3 0.13 11.6 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.6 AII58137.1 - 0.027 14.9 1.8 0.043 14.3 0.4 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 AII58137.1 - 0.028 14.8 0.0 0.068 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.6 AII58137.1 - 0.046 13.4 0.2 0.086 12.5 0.2 1.4 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 AII58137.1 - 0.14 12.2 0.0 0.54 10.3 0.0 2.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_membrane PF00664.23 AII58138.1 - 1e-59 202.5 18.8 1.4e-59 202.0 18.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 AII58138.1 - 4.1e-32 111.6 0.0 8.2e-32 110.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA PF00004.29 AII58138.1 - 5.4e-05 23.6 0.5 0.00041 20.8 0.5 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AII58138.1 - 0.00032 21.0 0.3 0.0032 17.7 0.3 2.3 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 AII58138.1 - 0.00038 20.4 0.0 0.0012 18.7 0.0 1.9 1 0 0 1 1 1 1 NTPase AAA_24 PF13479.6 AII58138.1 - 0.00066 19.5 0.1 0.0014 18.4 0.1 1.6 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 AII58138.1 - 0.0012 18.4 1.4 0.08 12.4 1.4 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 AII58138.1 - 0.0059 16.3 1.2 0.05 13.3 0.6 2.5 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.17 AII58138.1 - 0.0062 16.7 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_16 PF13191.6 AII58138.1 - 0.0077 16.6 0.0 0.019 15.3 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain ResIII PF04851.15 AII58138.1 - 0.012 15.7 0.1 0.033 14.2 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_14 PF13173.6 AII58138.1 - 0.019 15.0 0.1 0.66 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 AII58138.1 - 0.022 15.3 0.0 0.045 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 AII58138.1 - 0.024 14.6 0.0 0.058 13.4 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 AII58138.1 - 0.025 14.6 0.7 0.83 9.7 0.7 2.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 AII58138.1 - 0.029 13.9 0.1 0.1 12.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region DEAD PF00270.29 AII58138.1 - 0.04 13.7 0.1 2.6 7.8 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_21 PF13304.6 AII58138.1 - 0.043 13.6 0.1 10 5.8 0.0 2.2 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 AII58138.1 - 0.05 13.5 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase cobW PF02492.19 AII58138.1 - 0.057 13.0 0.1 0.25 10.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 AII58138.1 - 0.076 13.5 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AII58138.1 - 0.076 12.8 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 AII58138.1 - 0.095 12.6 0.0 0.26 11.2 0.0 1.8 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_33 PF13671.6 AII58138.1 - 0.15 12.2 0.3 0.48 10.6 0.3 1.9 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 AII58138.1 - 0.23 11.7 0.4 1.1 9.4 0.2 2.1 1 1 0 2 2 2 0 AAA domain DUF2207 PF09972.9 AII58138.1 - 7 5.3 13.6 0.56 8.9 0.8 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Fer4 PF00037.27 AII58139.1 - 1.9e-10 40.1 10.1 4.5e-05 23.1 0.7 2.1 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AII58139.1 - 2.8e-09 37.4 30.2 2.3e-05 24.9 11.5 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 AII58139.1 - 5.2e-09 35.8 8.0 0.00029 20.8 2.3 2.1 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 AII58139.1 - 2e-08 34.2 19.2 7.2e-07 29.2 7.9 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 AII58139.1 - 1.3e-06 28.8 3.2 0.011 16.2 0.3 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AII58139.1 - 3.7e-06 27.8 5.3 0.0057 17.6 3.1 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 AII58139.1 - 4.7e-06 26.6 4.8 0.0042 17.2 2.0 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AII58139.1 - 1.2e-05 25.1 10.4 0.00067 19.6 2.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 AII58139.1 - 1.3e-05 25.3 6.9 9.8e-05 22.4 7.3 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AII58139.1 - 2.1e-05 24.9 3.6 0.015 15.8 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.6 AII58139.1 - 3.9e-05 24.3 3.8 0.024 15.3 0.8 2.2 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_22 PF17179.4 AII58139.1 - 5e-05 24.1 3.0 0.051 14.4 0.4 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 AII58139.1 - 0.00064 20.0 7.7 0.014 15.9 2.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.6 AII58139.1 - 0.0027 18.2 4.5 0.43 11.2 0.0 2.3 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 AII58139.1 - 0.28 12.2 13.8 0.62 11.1 6.0 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain BioY PF02632.14 AII58140.1 - 4.4e-28 98.0 21.0 6.3e-28 97.5 21.0 1.2 1 0 0 1 1 1 1 BioY family zf-ribbon_3 PF13248.6 AII58141.1 - 0.029 13.8 0.2 0.049 13.0 0.2 1.3 1 0 0 1 1 1 0 zinc-ribbon domain Rhodanese_C PF12368.8 AII58141.1 - 0.089 13.2 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Rhodanase C-terminal GTP_EFTU_D2 PF03144.25 AII58142.1 - 6.2e-07 29.7 0.1 1.2e-06 28.8 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 AII58142.1 - 0.031 14.2 0.1 0.045 13.7 0.1 1.5 1 1 0 1 1 1 0 Elongation factor Tu domain 4 CusF_Ec PF11604.8 AII58142.1 - 0.061 13.3 0.1 4.6 7.3 0.0 2.4 1 1 1 2 2 2 0 Copper binding periplasmic protein CusF tRNA_anti-codon PF01336.25 AII58142.1 - 0.076 13.0 0.1 0.21 11.6 0.0 1.8 1 1 1 2 2 2 0 OB-fold nucleic acid binding domain DMRL_synthase PF00885.19 AII58143.1 - 6e-60 201.2 0.1 6.7e-60 201.0 0.1 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase DHBP_synthase PF00926.19 AII58144.1 - 1.6e-82 275.7 0.7 2.3e-82 275.2 0.7 1.2 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase GTP_cyclohydro2 PF00925.20 AII58144.1 - 4.6e-75 250.7 0.0 8.5e-75 249.8 0.0 1.4 1 0 0 1 1 1 1 GTP cyclohydrolase II Lum_binding PF00677.17 AII58145.1 - 3.3e-41 139.2 0.1 3e-20 72.0 0.1 2.1 2 0 0 2 2 2 2 Lumazine binding domain RibD_C PF01872.17 AII58146.1 - 4.5e-46 157.2 0.0 6.1e-46 156.8 0.0 1.2 1 0 0 1 1 1 1 RibD C-terminal domain dCMP_cyt_deam_1 PF00383.23 AII58146.1 - 3.5e-20 71.7 0.2 6.5e-20 70.9 0.2 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 AII58146.1 - 1.1e-13 51.1 0.1 1.7e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 MafB19-like deaminase Inv-AAD PF18785.1 AII58146.1 - 4e-07 29.9 0.1 9.7e-06 25.5 0.1 2.4 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase SIMPL PF04402.14 AII58147.1 - 7.5e-50 170.2 5.6 8.6e-50 170.0 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Lipase_GDSL_2 PF13472.6 AII58147.1 - 0.09 13.2 1.8 0.19 12.1 1.8 1.6 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Peptidase_S24 PF00717.23 AII58148.1 - 3.2e-18 65.4 0.2 5.3e-18 64.7 0.2 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 AII58148.1 - 1.5e-09 37.7 0.0 3.4e-09 36.6 0.0 1.6 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Pribosyltran PF00156.27 AII58149.1 - 1.8e-20 73.1 0.2 3.3e-20 72.2 0.2 1.3 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AII58149.1 - 0.047 13.1 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Endonuc_Holl PF10107.9 AII58150.1 - 2.9e-34 118.3 0.0 3.5e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Endonuclease related to archaeal Holliday junction resolvase UPF0102 PF02021.17 AII58150.1 - 0.057 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0102 MLANA PF14991.6 AII58150.1 - 0.13 12.5 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein melan-A MutL_C PF08676.11 AII58151.1 - 3.6e-38 130.6 0.1 6e-38 129.9 0.1 1.4 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 AII58151.1 - 3.2e-35 120.4 0.0 4.9e-35 119.8 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 AII58151.1 - 1.2e-08 34.8 0.0 1.4e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 AII58151.1 - 0.00019 21.9 0.0 0.00043 20.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UvrD-helicase PF00580.21 AII58152.1 - 2.9e-76 257.0 0.0 7.2e-76 255.7 0.0 1.7 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 AII58152.1 - 4.5e-69 233.5 0.1 4e-68 230.4 0.0 2.2 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 AII58152.1 - 3.6e-37 127.9 0.0 7e-37 127.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 AII58152.1 - 8.9e-13 47.9 0.1 3.1e-12 46.1 0.1 2.0 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 AII58152.1 - 1.9e-07 31.0 0.0 0.00023 21.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 AII58152.1 - 6.3e-06 26.1 0.2 0.11 12.2 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 AII58152.1 - 0.0018 18.0 0.2 4.4 6.9 0.1 3.4 2 1 1 3 3 3 1 AAA domain AAA_11 PF13086.6 AII58152.1 - 0.014 15.2 0.0 0.032 14.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF4962 PF16332.5 AII58152.1 - 0.044 12.3 0.0 0.86 8.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4962) Pribosyltran PF00156.27 AII58153.1 - 1.1e-18 67.3 0.1 1.3e-18 67.0 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 AII58153.1 - 0.00014 21.4 0.0 0.00021 20.8 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 AII58153.1 - 0.009 15.5 0.0 0.031 13.8 0.0 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase OTCace_N PF02729.21 AII58154.1 - 3.2e-40 137.6 0.0 4.9e-40 137.0 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 AII58154.1 - 2.7e-34 118.5 0.0 4.1e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Amidohydro_1 PF01979.20 AII58155.1 - 1.9e-32 113.0 0.1 2.6e-32 112.5 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 AII58155.1 - 1.1e-16 61.5 0.1 3.7e-07 30.0 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family DHOase PF12890.7 AII58155.1 - 2.6e-16 59.8 0.0 3.8e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Dihydro-orotase-like CPSase_sm_chain PF00988.22 AII58156.1 - 4.3e-50 168.8 0.0 6.6e-50 168.2 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 AII58156.1 - 1.8e-46 158.3 0.0 2.6e-46 157.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AII58156.1 - 2.7e-05 24.0 0.3 0.016 15.0 0.2 2.6 1 1 1 2 2 2 1 Peptidase C26 CPSase_L_D2 PF02786.17 AII58157.1 - 6.4e-116 385.2 0.1 1.4e-76 256.7 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 AII58157.1 - 1.1e-42 145.2 0.1 2.4e-42 144.1 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain MGS PF02142.22 AII58157.1 - 7.6e-20 70.9 0.2 5.6e-19 68.1 0.0 2.6 3 0 0 3 3 2 1 MGS-like domain Dala_Dala_lig_C PF07478.13 AII58157.1 - 9.4e-17 61.2 0.0 4e-07 29.8 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 AII58157.1 - 2.8e-16 59.6 0.0 8.3e-07 28.7 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 AII58157.1 - 4.8e-14 52.2 0.0 5.8e-07 29.3 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 AII58157.1 - 6e-13 49.1 0.1 6.9e-06 26.2 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 AII58157.1 - 1.8e-11 44.2 0.0 2.3e-07 30.8 0.0 2.4 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.6 AII58157.1 - 5.1e-09 35.9 0.0 0.0022 17.5 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_4 PF13535.6 AII58157.1 - 6.1e-06 25.9 0.4 0.022 14.4 0.0 3.4 3 1 0 3 3 3 2 ATP-grasp domain ATP-grasp_2 PF08442.10 AII58157.1 - 4.9e-05 23.0 0.0 0.019 14.5 0.0 3.0 2 0 0 2 2 2 1 ATP-grasp domain DUF4176 PF13780.6 AII58157.1 - 0.033 14.2 0.0 5.6 7.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4176) PrpR_N PF06506.11 AII58157.1 - 0.097 12.2 0.1 2.1 7.9 0.0 3.1 3 0 0 3 3 3 0 Propionate catabolism activator DHODB_Fe-S_bind PF10418.9 AII58158.1 - 2.9e-14 52.6 4.5 2.9e-14 52.6 4.5 1.8 2 0 0 2 2 2 1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B NAD_binding_1 PF00175.21 AII58158.1 - 3.4e-06 27.7 0.0 2.8e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 AII58158.1 - 0.00037 20.8 0.0 0.0014 18.9 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Fer2 PF00111.27 AII58158.1 - 0.11 12.4 1.3 0.43 10.6 0.5 2.2 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain GTP_cyclohydroI PF01227.22 AII58159.1 - 1.2e-76 256.1 0.0 1.4e-76 256.0 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I PALP PF00291.25 AII58160.1 - 5.3e-69 232.9 2.5 6.1e-69 232.7 2.5 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Asparaginase_C PF17763.1 AII58160.1 - 0.11 12.7 0.2 0.21 11.8 0.2 1.5 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain Homoserine_dh PF00742.19 AII58161.1 - 3.5e-59 199.6 0.0 5.6e-59 198.9 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase ACT PF01842.25 AII58161.1 - 4.6e-12 45.5 0.0 1.3e-11 44.0 0.0 1.8 1 0 0 1 1 1 1 ACT domain NAD_binding_3 PF03447.16 AII58161.1 - 3.5e-10 40.5 0.1 9.4e-10 39.2 0.0 1.8 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain ACT_4 PF13291.6 AII58161.1 - 0.00051 20.6 0.1 0.0011 19.5 0.1 1.6 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 AII58161.1 - 0.016 15.2 0.6 0.37 10.8 0.2 2.3 2 0 0 2 2 2 0 ACT domain ACT_7 PF13840.6 AII58161.1 - 0.086 12.6 0.1 0.29 10.9 0.1 1.9 1 0 0 1 1 1 0 ACT domain Rotamase PF00639.21 AII58162.1 - 4.5e-10 40.4 0.2 9.7e-05 23.3 0.0 3.1 4 0 0 4 4 4 2 PPIC-type PPIASE domain Rotamase_3 PF13616.6 AII58162.1 - 7.5e-06 26.5 0.1 0.02 15.4 0.0 2.9 2 1 1 3 3 3 2 PPIC-type PPIASE domain SurA_N_3 PF13624.6 AII58162.1 - 0.015 15.1 1.9 0.045 13.6 0.5 2.4 1 1 1 2 2 2 0 SurA N-terminal domain SurA_N PF09312.11 AII58162.1 - 0.072 13.2 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 SurA N-terminal domain Med12 PF09497.10 AII58162.1 - 0.076 13.3 0.0 16 5.9 0.2 2.6 2 0 0 2 2 2 0 Transcription mediator complex subunit Med12 SurA_N_2 PF13623.6 AII58162.1 - 0.1 12.4 0.2 0.31 10.9 0.2 1.8 1 1 0 1 1 1 0 SurA N-terminal domain Phage_holin_3_6 PF07332.11 AII58162.1 - 0.12 12.4 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Coiled-coil_56 PF09813.9 AII58162.1 - 0.12 12.4 0.4 0.31 11.1 0.1 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 NTP_transferase PF00483.23 AII58163.1 - 1.6e-48 165.4 0.0 2.2e-48 165.0 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 AII58163.1 - 1.2e-13 50.2 12.7 5.6e-08 32.2 1.9 4.3 1 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 AII58163.1 - 3.7e-09 37.1 0.0 4.6e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 AII58163.1 - 1.7e-06 27.6 17.9 0.0001 22.0 5.9 4.1 3 2 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 AII58163.1 - 0.14 10.3 2.6 0.2 9.7 1.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4954) AMP-binding PF00501.28 AII58164.1 - 4.2e-93 312.2 0.0 5.2e-93 311.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 AII58164.1 - 1.9e-24 86.4 2.0 3.7e-24 85.5 2.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 AII58164.1 - 5.6e-22 77.4 2.0 1.4e-21 76.2 2.0 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus PCRF PF03462.18 AII58165.1 - 1.6e-68 230.4 1.2 1.6e-68 230.4 1.2 1.8 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 AII58165.1 - 3.6e-37 126.8 0.6 3.6e-37 126.8 0.6 2.2 2 1 1 3 3 3 1 RF-1 domain ABC_tran_CTD PF16326.5 AII58165.1 - 0.024 14.9 0.7 0.024 14.9 0.7 3.4 2 1 2 4 4 4 0 ABC transporter C-terminal domain DUF2175 PF09943.9 AII58165.1 - 0.3 11.4 4.8 0.16 12.3 1.9 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Apt1 PF10351.9 AII58165.1 - 0.41 9.4 3.9 0.79 8.5 3.9 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain AAA_23 PF13476.6 AII58165.1 - 9.2 6.7 9.3 41 4.6 0.1 2.4 2 1 0 2 2 2 0 AAA domain PrmC_N PF17827.1 AII58166.1 - 9.7e-17 61.3 4.1 2.4e-16 60.1 1.5 2.6 3 1 0 3 3 2 1 PrmC N-terminal domain Methyltransf_31 PF13847.6 AII58166.1 - 7.6e-11 42.0 0.0 1.3e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 AII58166.1 - 1e-10 41.5 0.0 1.7e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 AII58166.1 - 4e-09 37.0 0.0 9.4e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 AII58166.1 - 4.8e-09 36.3 0.0 8.9e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 AII58166.1 - 1.1e-08 34.9 0.0 1.7e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 AII58166.1 - 2e-05 25.2 0.0 4.4e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 AII58166.1 - 4.8e-05 23.0 0.0 7.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.12 AII58166.1 - 6.9e-05 23.4 0.0 0.00016 22.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 AII58166.1 - 0.00013 21.7 0.0 0.00029 20.6 0.0 1.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.6 AII58166.1 - 0.00022 21.3 0.0 0.00034 20.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TrmK PF04816.12 AII58166.1 - 0.0097 15.5 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 tRNA (adenine(22)-N(1))-methyltransferase Met_10 PF02475.16 AII58166.1 - 0.01 15.6 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_16 PF10294.9 AII58166.1 - 0.013 15.3 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase rRNA_methylase PF06962.12 AII58166.1 - 0.023 14.6 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative rRNA methylase Methyltransf_2 PF00891.18 AII58166.1 - 0.038 13.3 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_4 PF02390.17 AII58166.1 - 0.067 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase CheR PF01739.18 AII58166.1 - 0.073 12.5 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain TM1506 PF08973.10 AII58166.1 - 0.084 12.5 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1893) GidB PF02527.15 AII58166.1 - 0.12 11.7 0.0 0.26 10.6 0.0 1.5 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G EFG_IV PF03764.18 AII58167.1 - 3.2e-44 149.6 0.1 6.3e-44 148.6 0.1 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU PF00009.27 AII58167.1 - 1.3e-43 148.8 0.0 2.1e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 AII58167.1 - 2.2e-28 98.1 0.0 5.7e-28 96.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 AII58167.1 - 4e-25 87.7 0.0 1.1e-24 86.3 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 AII58167.1 - 1.7e-05 25.1 0.1 4.4e-05 23.8 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 AII58167.1 - 0.00011 22.1 0.0 0.00023 21.0 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 AII58167.1 - 0.0065 16.5 0.0 0.023 14.7 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP-grasp_4 PF13535.6 AII58167.1 - 0.083 12.5 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 ATP-grasp domain SpoIIM PF01944.17 AII58168.1 - 3e-25 89.1 15.5 3.8e-25 88.8 15.5 1.0 1 0 0 1 1 1 1 Stage II sporulation protein M DUF4366 PF14283.6 AII58169.1 - 0.0093 16.0 0.3 0.011 15.8 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Phage_integrase PF00589.22 AII58170.1 - 2.2e-49 167.5 0.0 4.2e-49 166.6 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 AII58170.1 - 1.9e-18 66.5 0.1 3.8e-17 62.4 0.0 2.7 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 AII58170.1 - 3.5e-09 37.0 1.5 2.2e-08 34.5 0.6 2.7 2 1 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 AII58170.1 - 0.00049 20.4 1.4 0.56 10.6 0.0 2.8 3 0 0 3 3 3 2 Phage integrase SAM-like domain DUF3435 PF11917.8 AII58170.1 - 0.038 12.9 0.0 0.065 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Integrase_1 PF12835.7 AII58170.1 - 0.11 12.6 0.1 0.29 11.2 0.1 1.8 1 1 0 1 1 1 0 Integrase TPR_15 PF13429.6 AII58170.1 - 0.12 11.6 0.6 0.21 10.7 0.1 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat UvrC_HhH_N PF08459.11 AII58171.1 - 2.6e-51 173.6 0.0 6.6e-51 172.3 0.0 1.7 2 0 0 2 2 2 1 UvrC Helix-hairpin-helix N-terminal UVR PF02151.19 AII58171.1 - 6.4e-10 38.5 3.1 3.5e-08 32.9 1.5 2.9 2 0 0 2 2 2 1 UvrB/uvrC motif HHH_2 PF12826.7 AII58171.1 - 3.4e-08 33.5 0.0 1.2e-07 31.7 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 AII58171.1 - 2.8e-07 31.1 0.3 2.8e-07 31.1 0.3 2.3 3 0 0 3 3 3 1 Helix-hairpin-helix domain GIY-YIG PF01541.24 AII58171.1 - 3e-07 30.6 0.0 8.4e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 GIY-YIG catalytic domain HHH PF00633.23 AII58171.1 - 0.001 18.9 0.1 0.3 11.0 0.0 2.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 AII58171.1 - 0.069 13.8 0.1 0.51 11.0 0.0 2.5 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold HHH_3 PF12836.7 AII58171.1 - 0.077 13.3 0.1 0.42 10.9 0.1 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif Acetyltransf_9 PF13527.7 AII58172.1 - 2.8e-07 30.7 0.0 3.9e-07 30.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AII58172.1 - 3.4e-05 24.0 0.0 4.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AII58172.1 - 0.00038 20.4 0.0 0.00063 19.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AII58172.1 - 0.0021 18.5 0.0 0.003 17.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AII58172.1 - 0.051 13.5 0.0 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_CG PF14542.6 AII58172.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Hydrolase_3 PF08282.12 AII58173.1 - 8.2e-55 186.3 0.0 9.4e-55 186.1 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 AII58173.1 - 5e-12 45.9 0.0 3.3e-08 33.4 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 AII58173.1 - 4e-08 33.8 0.7 0.0024 18.2 0.0 3.3 2 2 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 AII58173.1 - 6.8e-07 29.9 0.1 0.014 15.8 0.0 3.3 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 AII58173.1 - 0.0035 17.4 0.0 0.0064 16.6 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 AII58173.1 - 0.15 12.1 0.3 22 5.1 0.0 2.8 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Mu-like_Pro PF10123.9 AII58173.1 - 0.19 11.2 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Mu-like prophage I protein MutS_V PF00488.21 AII58174.1 - 4.9e-82 274.5 0.1 9.1e-82 273.7 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 AII58174.1 - 1.1e-41 141.6 0.0 2.4e-41 140.5 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 AII58174.1 - 2.7e-38 132.1 0.1 6.7e-38 130.8 0.1 1.7 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 AII58174.1 - 1.5e-28 99.0 0.2 7.6e-28 96.7 0.1 2.3 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.17 AII58174.1 - 8.3e-22 77.9 0.5 1.9e-21 76.8 0.5 1.6 1 0 0 1 1 1 1 MutS domain II AAA_27 PF13514.6 AII58174.1 - 0.00099 18.8 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 AII58174.1 - 0.027 14.5 0.0 0.082 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AII58174.1 - 0.066 13.7 0.2 0.33 11.5 0.0 2.3 3 0 0 3 3 3 0 ABC transporter AAA_29 PF13555.6 AII58174.1 - 0.095 12.5 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 AII58174.1 - 1 9.8 0.0 1 9.8 0.0 3.2 4 1 0 4 4 4 0 AAA domain DUF2593 PF10767.9 AII58176.1 - 0.018 15.1 1.3 0.36 10.9 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2593) ABC2_membrane_3 PF12698.7 AII58176.1 - 1.9 7.5 10.7 2.5 7.1 10.7 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Tetraspanin PF00335.20 AII58176.1 - 2.5 7.8 7.6 4 7.1 7.6 1.4 1 1 0 1 1 1 0 Tetraspanin family FAA_hydrolase PF01557.18 AII58177.1 - 7e-62 208.9 0.0 8.3e-62 208.7 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2437 PF10370.9 AII58177.1 - 4.5e-13 49.9 0.0 1.2e-12 48.5 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF2437) CobA_CobO_BtuR PF02572.15 AII58178.1 - 2.8e-58 197.0 0.1 3.1e-58 196.8 0.1 1.0 1 0 0 1 1 1 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP FBPase_3 PF01950.16 AII58179.1 - 4.8e-185 614.9 0.0 5.5e-185 614.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-1,6-bisphosphatase Ham1p_like PF01725.16 AII58180.1 - 7.9e-59 198.7 0.0 8.8e-59 198.6 0.0 1.0 1 0 0 1 1 1 1 Ham1 family DNA_pol3_beta_2 PF02767.16 AII58181.1 - 1.6e-32 112.1 0.5 6.6e-27 94.0 0.1 2.3 2 0 0 2 2 2 2 DNA polymerase III beta subunit, central domain DNA_pol3_beta PF00712.19 AII58181.1 - 1.8e-29 102.3 0.3 6.5e-21 74.7 0.0 3.3 3 0 0 3 3 3 3 DNA polymerase III beta subunit, N-terminal domain DNA_pol3_beta_3 PF02768.15 AII58181.1 - 7.1e-29 100.1 0.3 2.9e-25 88.5 0.0 3.2 3 1 0 3 3 3 2 DNA polymerase III beta subunit, C-terminal domain ParE_toxin PF05016.15 AII58183.1 - 1.4e-13 51.2 0.8 1.6e-13 51.0 0.8 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE ParE-like_toxin PF15781.5 AII58183.1 - 0.00012 22.0 0.2 0.00038 20.3 0.2 1.7 1 1 0 1 1 1 1 ParE-like toxin of type II bacterial toxin-antitoxin system Gp49 PF05973.14 AII58183.1 - 0.0011 19.1 0.0 0.0013 18.8 0.0 1.2 1 0 0 1 1 1 1 Phage derived protein Gp49-like (DUF891) Rep_trans PF02486.19 AII58184.1 - 0.13 11.9 5.6 0.26 11.0 5.6 1.5 1 1 0 1 1 1 0 Replication initiation factor ResIII PF04851.15 AII58185.1 - 3.6e-17 62.9 0.7 1.2e-16 61.2 0.4 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 AII58185.1 - 0.006 16.3 0.4 0.031 13.9 0.4 2.0 1 1 0 1 1 1 1 SWI2/SNF2 ATPase DEAD PF00270.29 AII58185.1 - 0.0061 16.4 0.1 0.03 14.1 0.1 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 AII58185.1 - 0.0088 16.3 0.0 0.22 11.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 AII58185.1 - 0.015 14.8 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 AII58185.1 - 0.07 12.4 0.4 0.24 10.6 0.4 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) N6_N4_Mtase PF01555.18 AII58186.1 - 5.1e-33 114.7 0.7 1.4e-32 113.3 0.2 1.9 2 0 0 2 2 2 1 DNA methylase UPF0020 PF01170.18 AII58186.1 - 5.7e-05 22.9 0.1 0.013 15.2 0.1 2.4 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 AII58186.1 - 0.015 16.0 0.0 0.051 14.3 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain SnoaL_4 PF13577.6 AII58188.1 - 0.051 13.7 0.0 0.051 13.7 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain Tom7 PF08038.12 AII58188.1 - 0.082 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 TOM7 family HATPase_c PF02518.26 AII58189.1 - 1.1e-24 87.0 0.1 2e-24 86.3 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AII58189.1 - 3.3e-15 55.9 1.1 6.3e-15 55.0 0.4 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 AII58189.1 - 1.3e-07 31.8 0.1 8.3e-07 29.3 0.0 2.3 2 0 0 2 2 2 1 HAMP domain HATPase_c_5 PF14501.6 AII58189.1 - 0.024 14.5 0.0 0.056 13.4 0.0 1.6 1 0 0 1 1 1 0 GHKL domain NUMOD1 PF07453.13 AII58189.1 - 0.074 13.3 0.3 0.17 12.2 0.3 1.7 1 0 0 1 1 1 0 NUMOD1 domain HATPase_c_2 PF13581.6 AII58189.1 - 0.18 11.7 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Response_reg PF00072.24 AII58190.1 - 3.3e-24 85.2 0.0 7.5e-24 84.1 0.0 1.6 2 0 0 2 2 2 1 Response regulator receiver domain Trans_reg_C PF00486.28 AII58190.1 - 6.2e-19 67.9 0.0 1.6e-18 66.5 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal CENP-K PF11802.8 AII58190.1 - 0.11 12.1 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Centromere-associated protein K FleQ PF06490.11 AII58190.1 - 0.18 12.2 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ RP854 PF17460.2 AII58190.1 - 0.18 11.5 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein RP854 Inhibitor_I36 PF03995.13 AII58191.1 - 0.0021 18.0 0.6 0.0077 16.1 0.2 2.1 1 1 1 2 2 2 1 Peptidase inhibitor family I36 Crystall PF00030.19 AII58191.1 - 0.0057 16.8 0.1 0.027 14.7 0.0 2.1 2 0 0 2 2 2 1 Beta/Gamma crystallin DUF1514 PF07438.11 AII58191.1 - 0.0088 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1514) PLDc_N PF13396.6 AII58192.1 - 1.5e-05 24.8 1.4 1.5e-05 24.8 1.4 2.0 2 0 0 2 2 2 1 Phospholipase_D-nuclease N-terminal UL41A PF17591.2 AII58192.1 - 1.5 9.0 5.6 0.33 11.1 1.4 1.9 1 1 1 2 2 2 0 Herpesvirus UL41A DUF2517 PF10725.9 AII58193.1 - 0.043 13.6 0.5 0.18 11.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2517) Laminin_G_3 PF13385.6 AII58195.1 - 5.6e-29 101.3 3.1 8.8e-29 100.6 3.1 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Sialidase PF02973.16 AII58195.1 - 0.00028 20.5 0.1 0.00094 18.7 0.0 2.0 2 1 0 2 2 2 1 Sialidase, N-terminal domain DUF1080 PF06439.11 AII58195.1 - 0.0024 18.0 0.7 0.0053 16.9 0.7 1.6 1 1 0 1 1 1 1 Domain of Unknown Function (DUF1080) DUF1801 PF08818.11 AII58196.1 - 4.2e-16 59.2 0.0 5e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DU1801) Smr PF01713.21 AII58197.1 - 1.2e-12 48.0 0.1 1.4e-12 47.8 0.1 1.0 1 0 0 1 1 1 1 Smr domain Formyl_trans_N PF00551.19 AII58198.1 - 4.5e-43 147.1 0.0 6.4e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 AII58198.1 - 0.00081 19.1 0.0 0.0019 17.9 0.0 1.6 1 0 0 1 1 1 1 ACT domain Pro_isomerase PF00160.21 AII58200.1 - 2e-42 145.1 0.2 2.5e-42 144.8 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SBF PF01758.16 AII58201.1 - 1.7e-63 213.9 12.5 1.7e-63 213.9 12.5 1.8 2 0 0 2 2 2 1 Sodium Bile acid symporter family PMSR PF01625.21 AII58202.1 - 9.5e-64 214.2 0.0 1.1e-63 214.0 0.0 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase SelR PF01641.18 AII58203.1 - 4.4e-43 146.2 0.0 5.2e-43 146.0 0.0 1.0 1 0 0 1 1 1 1 SelR domain zf-RRN7 PF11781.8 AII58203.1 - 0.002 17.7 1.1 0.041 13.6 0.2 2.3 2 0 0 2 2 2 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Ribosomal_L37e PF01907.19 AII58203.1 - 0.0084 16.3 3.3 0.089 13.0 0.8 2.2 2 0 0 2 2 2 1 Ribosomal protein L37e Tnp_zf-ribbon_2 PF13842.6 AII58203.1 - 0.011 16.5 0.2 4.1 8.3 0.0 2.5 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon Yippee-Mis18 PF03226.14 AII58203.1 - 0.028 14.6 0.1 0.76 10.0 0.0 2.1 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-HIT PF04438.16 AII58203.1 - 0.04 13.8 3.5 0.065 13.1 0.5 2.2 2 0 0 2 2 2 0 HIT zinc finger GFA PF04828.14 AII58203.1 - 0.053 13.9 0.5 1.1 9.7 0.1 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme TF_Zn_Ribbon PF08271.12 AII58203.1 - 0.068 12.7 0.6 7.8 6.1 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding DZR PF12773.7 AII58203.1 - 0.07 13.2 2.2 0.54 10.3 1.0 2.2 1 1 2 3 3 3 0 Double zinc ribbon zf-CCHC_2 PF13696.6 AII58203.1 - 0.088 12.7 0.9 0.088 12.7 0.9 2.0 2 0 0 2 2 2 0 Zinc knuckle zf-Mss51 PF13824.6 AII58203.1 - 0.19 11.9 1.8 0.69 10.1 0.3 2.4 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 FMN_red PF03358.15 AII58204.1 - 1.2e-31 109.6 0.0 1.4e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 AII58204.1 - 2.6e-09 37.1 0.0 3e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.7 AII58204.1 - 0.12 12.6 0.1 0.3 11.3 0.0 1.6 2 0 0 2 2 2 0 Flavodoxin domain TfoX_N PF04993.13 AII58205.1 - 3.9e-21 75.1 0.1 4.8e-21 74.8 0.1 1.1 1 0 0 1 1 1 1 TfoX N-terminal domain Trigger_C PF05698.14 AII58206.1 - 0.013 15.5 0.3 0.017 15.1 0.3 1.3 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus ZapD PF07072.11 AII58206.1 - 0.016 15.0 0.1 0.021 14.6 0.1 1.1 1 0 0 1 1 1 0 Cell division protein Erv26 PF04148.13 AII58206.1 - 0.018 14.9 0.6 0.028 14.3 0.6 1.3 1 0 0 1 1 1 0 Transmembrane adaptor Erv26 DUF997 PF06196.12 AII58206.1 - 0.16 12.0 2.0 7.3 6.7 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF997) FWWh PF14922.6 AII58206.1 - 1.3 9.0 6.5 1.9 8.4 6.3 1.3 1 1 0 1 1 1 0 Protein of unknown function HTH_20 PF12840.7 AII58207.1 - 4.1e-17 62.0 0.0 5.4e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 AII58207.1 - 1.9e-13 50.0 0.0 7e-13 48.2 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 AII58207.1 - 1.4e-07 31.3 0.0 1.9e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 AII58207.1 - 7.1e-06 25.5 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 AII58207.1 - 0.0018 18.2 0.2 0.0032 17.4 0.0 1.5 2 0 0 2 2 2 1 HTH domain DprA_WH PF17782.1 AII58207.1 - 0.0018 18.3 0.0 0.0025 17.9 0.0 1.2 1 0 0 1 1 1 1 DprA winged helix domain HTH_IclR PF09339.10 AII58207.1 - 0.0028 17.4 0.1 0.0041 16.9 0.1 1.3 1 0 0 1 1 1 1 IclR helix-turn-helix domain TrmB PF01978.19 AII58207.1 - 0.024 14.5 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_Crp_2 PF13545.6 AII58207.1 - 0.032 14.2 0.0 0.046 13.7 0.0 1.3 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain Rrf2 PF02082.20 AII58207.1 - 0.039 14.3 0.0 0.052 13.9 0.0 1.3 1 1 0 1 1 1 0 Transcriptional regulator HTH_40 PF14493.6 AII58207.1 - 0.048 14.1 0.0 0.062 13.8 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain PaaX PF07848.12 AII58207.1 - 0.15 12.3 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 PaaX-like protein SdpI PF13630.6 AII58208.1 - 1.4e-18 66.7 4.9 1.4e-18 66.7 4.9 3.4 2 1 0 2 2 2 1 SdpI/YhfL protein family DUF1648 PF07853.11 AII58208.1 - 3.7e-16 58.5 3.5 1.3e-15 56.8 0.9 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1648) Phage_holin_2_2 PF10746.9 AII58208.1 - 0.018 14.7 1.6 0.018 14.7 1.6 1.9 2 0 0 2 2 2 0 Phage holin T7 family, holin superfamily II DUF2892 PF11127.8 AII58209.1 - 7.6e-20 70.7 2.0 8.2e-20 70.6 2.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2892) DUF373 PF04123.13 AII58209.1 - 0.023 14.2 1.9 0.024 14.1 1.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Pox_P21 PF05313.12 AII58209.1 - 0.038 13.6 1.5 0.037 13.6 1.5 1.0 1 0 0 1 1 1 0 Poxvirus P21 membrane protein SLATT_1 PF18181.1 AII58209.1 - 0.04 13.8 0.5 0.045 13.7 0.5 1.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 DUF2207 PF09972.9 AII58209.1 - 0.062 12.1 4.2 0.06 12.1 4.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2244 PF10003.9 AII58209.1 - 0.23 11.1 2.8 0.26 11.0 2.8 1.1 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) DUF2116 PF09889.9 AII58209.1 - 0.72 9.9 2.2 1.5 8.8 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) YtpI PF14007.6 AII58209.1 - 0.86 9.8 7.2 1.3 9.2 7.2 1.4 1 1 0 1 1 1 0 YtpI-like protein PhoR PF11808.8 AII58209.1 - 1.5 9.3 4.4 1.8 9.1 4.4 1.1 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR Smim3 PF17307.2 AII58209.1 - 6.7 6.3 8.7 0.4 10.2 2.4 1.9 1 1 1 2 2 2 0 Small integral membrane protein 3 FMN_red PF03358.15 AII58210.1 - 2.1e-30 105.5 0.0 2.6e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 AII58210.1 - 1.5e-16 60.7 0.0 1.9e-16 60.4 0.0 1.2 1 1 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.7 AII58210.1 - 0.065 13.5 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain PyrI_C PF02748.15 AII58212.1 - 0.027 14.4 0.1 0.052 13.5 0.0 1.5 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF3268 PF11672.8 AII58212.1 - 0.033 14.5 0.1 0.041 14.2 0.1 1.2 1 0 0 1 1 1 0 zinc-finger-containing domain T2SSE PF00437.20 AII58213.1 - 5.4e-41 140.5 0.4 1.1e-40 139.4 0.4 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 AII58213.1 - 0.00029 21.1 0.1 0.001 19.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AII58213.1 - 0.001 18.8 0.1 0.0023 17.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 AII58213.1 - 0.0066 16.3 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 AII58213.1 - 0.01 15.4 0.0 0.028 13.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 AII58213.1 - 0.015 15.8 0.2 0.019 15.5 0.2 1.5 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AII58213.1 - 0.017 14.4 0.0 0.16 11.2 0.0 2.4 2 1 0 2 2 2 0 Zeta toxin Rad17 PF03215.15 AII58213.1 - 0.017 15.1 0.0 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_19 PF13245.6 AII58213.1 - 0.017 15.5 0.0 0.064 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 AII58213.1 - 0.017 15.2 0.0 0.036 14.2 0.0 1.8 1 1 0 1 1 1 0 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 AII58213.1 - 0.02 14.2 0.3 0.076 12.3 0.2 1.8 1 1 0 1 1 1 0 FtsK/SpoIIIE family NTPase_1 PF03266.15 AII58213.1 - 0.021 14.8 0.2 1.3 8.9 0.0 2.7 3 0 0 3 3 3 0 NTPase CSTF_C PF14304.6 AII58213.1 - 0.032 13.8 1.5 0.079 12.6 1.5 1.6 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal AAA_30 PF13604.6 AII58213.1 - 0.043 13.5 0.0 0.2 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 AII58213.1 - 0.044 14.2 1.0 0.17 12.3 0.2 2.3 1 1 1 2 2 2 0 AAA ATPase domain AAA_14 PF13173.6 AII58213.1 - 0.066 13.2 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 AII58213.1 - 0.071 13.6 0.0 0.21 12.1 0.0 1.8 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.6 AII58213.1 - 0.092 12.9 0.1 0.22 11.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 AII58213.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit ArgJ PF01960.18 AII58214.1 - 8e-150 498.7 5.2 9e-150 498.6 5.2 1.0 1 0 0 1 1 1 1 ArgJ family AA_kinase PF00696.28 AII58215.1 - 1.8e-42 145.6 4.1 2e-42 145.4 4.1 1.0 1 0 0 1 1 1 1 Amino acid kinase family Aminotran_3 PF00202.21 AII58216.1 - 4e-111 371.6 0.1 5.1e-111 371.2 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-III DegT_DnrJ_EryC1 PF01041.17 AII58216.1 - 0.0015 17.9 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 AII58216.1 - 0.0025 16.8 0.0 0.0038 16.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Rapsyn_N PF10579.9 AII58217.1 - 0.067 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region Arginosuc_synth PF00764.19 AII58218.1 - 1.5e-174 580.9 0.0 1.7e-174 580.7 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase NHase_beta PF02211.15 AII58218.1 - 0.0028 17.7 0.0 0.0048 16.9 0.0 1.3 1 0 0 1 1 1 1 Nitrile hydratase beta subunit tRNA_Me_trans PF03054.16 AII58218.1 - 0.032 13.0 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase QueC PF06508.13 AII58218.1 - 0.037 13.5 0.1 0.079 12.5 0.0 1.6 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Lyase_1 PF00206.20 AII58219.1 - 3e-77 260.1 0.0 3.8e-77 259.7 0.0 1.1 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 AII58219.1 - 4e-17 62.7 0.0 1.1e-16 61.4 0.0 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Ubiq_cyt_C_chap PF03981.12 AII58219.1 - 0.12 12.4 0.0 0.83 9.7 0.0 2.3 3 0 0 3 3 3 0 Ubiquinol-cytochrome C chaperone Ribosomal_L28 PF00830.19 AII58220.1 - 8.3e-23 80.4 4.0 1e-22 80.1 4.0 1.0 1 0 0 1 1 1 1 Ribosomal L28 family Epiglycanin_C PF14654.6 AII58220.1 - 0.11 12.6 0.6 0.18 11.9 0.2 1.5 1 1 1 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region Dak1_2 PF13684.6 AII58221.1 - 1.3e-107 359.5 4.0 1.3e-107 359.5 4.0 1.5 2 0 0 2 2 2 1 Dihydroxyacetone kinase family Dak2 PF02734.17 AII58221.1 - 2.1e-41 141.7 1.1 4.3e-41 140.7 1.1 1.6 1 0 0 1 1 1 1 DAK2 domain TP_methylase PF00590.20 AII58221.1 - 0.0032 17.4 0.0 1.1 9.2 0.0 2.7 2 0 0 2 2 2 2 Tetrapyrrole (Corrin/Porphyrin) Methylases RuvX PF03652.15 AII58221.1 - 0.054 13.9 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 Holliday junction resolvase hGDE_central PF14702.6 AII58221.1 - 0.12 12.0 0.2 6.7 6.3 0.2 2.3 1 1 0 1 1 1 0 Central domain of human glycogen debranching enzyme DegV PF02645.16 AII58222.1 - 7.8e-80 268.2 0.1 8.7e-80 268.0 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein, DegV family COG1307 Dak1_2 PF13684.6 AII58222.1 - 3.8e-08 32.8 0.0 4.6e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Dihydroxyacetone kinase family DegV PF02645.16 AII58223.1 - 1e-76 258.0 0.0 1.1e-76 257.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein, DegV family COG1307 DegV PF02645.16 AII58224.1 - 1.4e-72 244.4 0.0 1.6e-72 244.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein, DegV family COG1307 DegV PF02645.16 AII58225.1 - 5.8e-68 229.2 1.1 6.6e-68 229.1 1.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein, DegV family COG1307 Dak1_2 PF13684.6 AII58225.1 - 1.9e-05 23.9 0.1 2.3e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 Dihydroxyacetone kinase family RecG_wedge PF17191.4 AII58226.1 - 8.9e-22 77.4 0.0 1.7e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 RecG wedge domain Helicase_C PF00271.31 AII58226.1 - 2.1e-21 76.3 0.2 4.1e-19 68.9 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 AII58226.1 - 8.1e-16 58.3 0.5 2.5e-14 53.4 0.2 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 AII58226.1 - 1.2e-08 35.1 0.0 2.3e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit tRNA_anti-codon PF01336.25 AII58226.1 - 0.00027 20.8 0.0 0.00079 19.4 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain ERCC3_RAD25_C PF16203.5 AII58226.1 - 0.014 14.6 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DNA_pol_lambd_f PF10391.9 AII58226.1 - 0.12 12.2 0.0 0.62 9.9 0.0 2.1 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda HNH PF01844.23 AII58227.1 - 1.6e-10 41.0 2.3 2.7e-10 40.3 2.3 1.4 1 0 0 1 1 1 1 HNH endonuclease HNH_5 PF14279.6 AII58227.1 - 6e-08 32.4 2.2 1e-07 31.7 2.2 1.4 1 0 0 1 1 1 1 HNH endonuclease SAD_SRA PF02182.17 AII58227.1 - 5.8e-05 22.8 0.0 9.2e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 SAD/SRA domain Endonuclease_7 PF02945.15 AII58227.1 - 0.12 12.3 0.2 0.28 11.2 0.2 1.5 1 0 0 1 1 1 0 Recombination endonuclease VII DALR_1 PF05746.15 AII58228.1 - 1.2e-36 125.5 0.2 2.7e-36 124.3 0.2 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain tRNA-synt_1d PF00750.19 AII58228.1 - 6.3e-23 81.3 0.0 8.6e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) Arg_tRNA_synt_N PF03485.16 AII58228.1 - 2.3e-21 76.2 0.1 2.7e-20 72.7 0.0 2.4 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1f PF01921.18 AII58228.1 - 0.00041 19.4 0.0 0.045 12.7 0.0 2.9 3 0 0 3 3 3 1 tRNA synthetases class I (K) tRNA-synt_1 PF00133.22 AII58228.1 - 0.001 17.4 0.0 0.014 13.7 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 AII58228.1 - 0.0012 18.3 0.0 1.2 8.4 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 AII58228.1 - 0.0063 15.3 0.3 0.29 9.8 0.0 3.1 2 2 1 3 3 3 1 tRNA synthetases class I (M) tRNA-synt_1c PF00749.21 AII58228.1 - 0.054 12.4 0.2 2.1 7.1 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain AsnC_trans_reg PF01037.21 AII58229.1 - 8.2e-10 38.5 0.0 9.4e-10 38.3 0.0 1.0 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain NapD PF03927.13 AII58229.1 - 0.0022 18.0 0.0 0.0028 17.7 0.0 1.1 1 0 0 1 1 1 1 NapD protein adh_short_C2 PF13561.6 AII58230.1 - 1.3e-60 204.9 0.1 1.5e-60 204.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AII58230.1 - 1.7e-12 47.3 0.1 2.3e-12 46.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Enoyl_reductase PF12241.8 AII58230.1 - 4.2e-06 26.3 0.0 0.014 14.8 0.0 2.1 2 0 0 2 2 2 2 Trans-2-enoyl-CoA reductase catalytic region NTase_sub_bind PF08780.11 AII58230.1 - 0.17 11.9 0.0 0.42 10.6 0.0 1.6 1 1 1 2 2 2 0 Nucleotidyltransferase substrate binding protein like AmoC PF04896.12 AII58231.1 - 0.0081 15.5 1.3 0.0088 15.3 1.3 1.0 1 0 0 1 1 1 1 Ammonia monooxygenase/methane monooxygenase, subunit C DUF2530 PF10745.9 AII58231.1 - 0.04 14.2 1.6 0.058 13.6 1.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2530) DUF4191 PF13829.6 AII58231.1 - 0.43 9.9 2.8 0.43 9.9 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Ribosomal_L32p PF01783.23 AII58232.1 - 1.8e-21 76.1 2.4 2.5e-21 75.7 2.4 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family Stc1 PF12898.7 AII58232.1 - 0.0021 18.6 0.8 0.0024 18.4 0.8 1.2 1 0 0 1 1 1 1 Stc1 domain MqsA_antitoxin PF15731.5 AII58232.1 - 0.029 14.5 0.3 0.038 14.1 0.3 1.2 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA zf-RING_7 PF02591.15 AII58232.1 - 0.15 12.3 2.5 0.25 11.6 0.1 2.2 2 0 0 2 2 2 0 C4-type zinc ribbon domain zf-ribbon_3 PF13248.6 AII58232.1 - 0.21 11.0 6.7 0.79 9.2 6.6 1.8 1 1 1 2 2 2 0 zinc-ribbon domain zf-RRN7 PF11781.8 AII58232.1 - 1.6 8.5 5.7 2.3 8.0 0.6 2.2 1 1 1 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Acyl_transf_1 PF00698.21 AII58233.1 - 2.8e-35 122.3 0.0 3.4e-35 122.1 0.0 1.0 1 0 0 1 1 1 1 Acyl transferase domain KH_1 PF00013.29 AII58233.1 - 0.028 14.3 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 KH domain DUF4140 PF13600.6 AII58233.1 - 0.041 14.3 0.0 0.078 13.4 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) MCM PF00493.23 AII58233.1 - 0.066 12.3 0.1 1.2 8.2 0.0 2.1 2 0 0 2 2 2 0 MCM P-loop domain adh_short_C2 PF13561.6 AII58234.1 - 4.8e-71 239.0 3.0 5.8e-71 238.8 3.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 AII58234.1 - 6.6e-64 215.0 1.3 8.3e-64 214.6 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 AII58234.1 - 3.7e-19 69.3 0.8 5.9e-19 68.7 0.8 1.4 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 AII58234.1 - 0.00059 19.2 0.3 0.0014 18.0 0.2 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 AII58234.1 - 0.014 14.9 0.1 0.042 13.3 0.1 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 AII58234.1 - 0.022 15.3 1.3 0.2 12.3 0.5 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NusB PF01029.18 AII58235.1 - 1.4e-38 132.2 0.5 1.6e-38 132.0 0.5 1.0 1 0 0 1 1 1 1 NusB family DnaB_2 PF07261.11 AII58235.1 - 0.026 14.2 0.0 0.058 13.1 0.0 1.7 1 1 1 2 2 2 0 Replication initiation and membrane attachment PP-binding PF00550.25 AII58236.1 - 3.9e-13 49.5 0.2 4.6e-13 49.3 0.2 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ribosomal_L50 PF10501.9 AII58236.1 - 0.0073 16.4 0.1 0.01 15.9 0.1 1.5 1 1 0 1 1 1 1 Ribosomal subunit 39S DUF4070 PF13282.6 AII58237.1 - 1.1e-39 135.7 0.2 1.3e-38 132.2 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4070) Radical_SAM PF04055.21 AII58237.1 - 5.1e-12 46.5 0.0 1.4e-11 45.0 0.0 1.8 1 1 1 2 2 2 1 Radical SAM superfamily B12-binding PF02310.19 AII58237.1 - 8.5e-10 38.7 0.0 2.9e-08 33.8 0.0 2.4 2 0 0 2 2 2 1 B12 binding domain CarD_CdnL_TRCF PF02559.16 AII58238.1 - 1.8e-25 89.5 0.0 4e-25 88.4 0.0 1.6 1 0 0 1 1 1 1 CarD-like/TRCF domain TRCF PF03461.15 AII58238.1 - 1.3e-21 76.7 0.0 4.1e-21 75.2 0.0 1.8 1 0 0 1 1 1 1 TRCF domain UvrB_inter PF17757.1 AII58238.1 - 1.3e-19 70.2 0.0 3e-19 69.0 0.0 1.7 1 0 0 1 1 1 1 UvrB interaction domain Helicase_C PF00271.31 AII58238.1 - 4.8e-19 68.7 2.1 4.4e-14 52.8 0.1 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.29 AII58238.1 - 1.4e-17 64.1 0.2 2.9e-17 63.0 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 AII58238.1 - 2.9e-07 30.6 0.0 6.7e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UB2H PF14814.6 AII58238.1 - 6.1e-05 23.0 0.0 0.00022 21.2 0.0 2.0 1 1 0 1 1 1 1 Bifunctional transglycosylase second domain SNF2_N PF00176.23 AII58238.1 - 0.0013 17.5 0.0 0.0018 17.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain AroM PF07302.11 AII58238.1 - 0.02 14.3 0.1 0.048 13.1 0.1 1.6 1 0 0 1 1 1 0 AroM protein AAA_22 PF13401.6 AII58238.1 - 0.11 12.8 0.2 0.62 10.3 0.2 2.3 1 1 0 1 1 1 0 AAA domain AA_kinase PF00696.28 AII58239.1 - 1e-43 149.7 1.4 1.5e-43 149.1 1.4 1.3 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 AII58239.1 - 9.4e-22 76.8 0.4 3.9e-21 74.8 0.1 2.2 2 0 0 2 2 2 1 PUA domain PUA_3 PF17785.1 AII58239.1 - 0.00026 20.7 0.1 0.00074 19.3 0.1 1.9 1 1 0 1 1 1 1 PUA-like domain Lon_2 PF13337.6 AII58239.1 - 0.067 11.7 0.0 0.09 11.3 0.0 1.1 1 0 0 1 1 1 0 Putative ATP-dependent Lon protease DUF5487 PF17589.2 AII58240.1 - 0.0043 17.3 0.0 0.0053 17.0 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5487) Trypsin_2 PF13365.6 AII58242.1 - 1.5e-28 100.6 0.3 3.3e-28 99.5 0.3 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 AII58242.1 - 3.9e-15 56.0 0.1 2.6e-14 53.3 0.0 2.3 2 0 0 2 2 2 1 PDZ domain Trypsin PF00089.26 AII58242.1 - 3.3e-14 53.2 0.1 8.2e-14 51.9 0.1 1.6 1 1 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 AII58242.1 - 3.8e-11 42.7 1.3 1.1e-09 38.0 0.0 3.1 3 0 0 3 3 3 1 PDZ domain PDZ PF00595.24 AII58242.1 - 1.5e-06 28.5 0.0 1.2e-05 25.5 0.0 2.6 3 0 0 3 3 3 1 PDZ domain Peptidase_S7 PF00949.21 AII58242.1 - 0.0075 16.1 0.1 0.019 14.8 0.1 1.6 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease Spc7 PF08317.11 AII58242.1 - 0.019 13.9 0.2 0.027 13.4 0.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Peptidase_S46 PF10459.9 AII58242.1 - 0.026 13.2 0.2 0.026 13.2 0.2 2.4 3 0 0 3 3 3 0 Peptidase S46 CENP-F_leu_zip PF10473.9 AII58242.1 - 0.027 14.5 0.3 0.04 14.0 0.3 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tricorn_PDZ PF14685.6 AII58242.1 - 0.035 14.1 0.1 0.35 10.9 0.0 2.4 2 1 0 2 2 2 0 Tricorn protease PDZ domain HemX PF04375.14 AII58242.1 - 0.076 12.3 3.6 0.1 11.8 3.6 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase NPV_P10 PF05531.12 AII58242.1 - 0.079 13.4 1.9 0.23 11.9 1.9 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein MscS_porin PF12795.7 AII58242.1 - 0.098 12.2 4.8 0.14 11.7 4.8 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Snf7 PF03357.21 AII58242.1 - 0.1 12.2 0.5 0.32 10.6 0.8 1.5 2 0 0 2 2 2 0 Snf7 HOOK PF05622.12 AII58242.1 - 0.15 10.1 0.1 0.21 9.7 0.1 1.0 1 0 0 1 1 1 0 HOOK protein FlaC_arch PF05377.11 AII58242.1 - 0.16 12.3 0.1 0.32 11.4 0.1 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) EzrA PF06160.12 AII58242.1 - 0.24 9.5 0.1 0.32 9.1 0.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Trypsin_2 PF13365.6 AII58243.1 - 2.6e-28 99.8 0.5 3.8e-28 99.3 0.5 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 AII58243.1 - 3.3e-12 46.7 0.1 1.5e-11 44.5 0.0 2.1 2 1 0 2 2 2 1 Trypsin HemX PF04375.14 AII58243.1 - 0.0011 18.3 0.3 0.0015 17.9 0.3 1.1 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase HsbA PF12296.8 AII58243.1 - 0.01 16.3 1.3 0.019 15.4 1.3 1.4 1 0 0 1 1 1 0 Hydrophobic surface binding protein A SLATT_6 PF18169.1 AII58243.1 - 0.017 14.8 0.1 0.025 14.2 0.1 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 DUF2304 PF10066.9 AII58243.1 - 0.029 14.6 0.4 0.057 13.6 0.4 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) Talin_middle PF09141.10 AII58243.1 - 0.071 13.1 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Talin, middle domain Phage_GP20 PF06810.11 AII58243.1 - 0.083 12.7 0.2 0.12 12.2 0.2 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 Prefoldin_2 PF01920.20 AII58243.1 - 0.087 12.8 1.6 0.5 10.3 0.1 2.0 1 1 1 2 2 2 0 Prefoldin subunit DHR10 PF18595.1 AII58243.1 - 0.1 12.7 0.4 0.14 12.2 0.4 1.1 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain NPV_P10 PF05531.12 AII58243.1 - 0.12 12.9 1.3 0.22 12.0 1.3 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Peptidase_S46 PF10459.9 AII58243.1 - 0.18 10.4 0.3 8.7 4.9 0.0 2.2 2 1 0 2 2 2 0 Peptidase S46 FlxA PF14282.6 AII58243.1 - 3.9 7.5 9.6 13 5.8 9.6 1.7 1 1 0 1 1 1 0 FlxA-like protein LPP PF04728.13 AII58243.1 - 6.8 7.2 7.7 1.1 9.6 1.7 2.1 1 1 1 2 2 2 0 Lipoprotein leucine-zipper TipAS PF07739.13 AII58244.1 - 5.1e-26 91.5 0.1 9.6e-26 90.6 0.1 1.5 1 0 0 1 1 1 1 TipAS antibiotic-recognition domain MerR_1 PF13411.6 AII58244.1 - 2.7e-16 59.4 7.7 1e-15 57.5 0.0 3.6 3 1 0 3 3 3 1 MerR HTH family regulatory protein MerR PF00376.23 AII58244.1 - 9e-13 47.8 0.1 9e-13 47.8 0.1 2.1 3 0 0 3 3 3 1 MerR family regulatory protein V-SNARE_C PF12352.8 AII58244.1 - 0.00043 20.5 2.5 0.033 14.5 0.6 2.3 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus MerR-DNA-bind PF09278.11 AII58244.1 - 0.00087 19.8 4.1 0.0032 18.0 1.0 3.0 2 2 1 3 3 3 1 MerR, DNA binding OmpH PF03938.14 AII58244.1 - 0.1 12.9 3.0 0.17 12.2 3.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Polyoma_coat2 PF00761.20 AII58244.1 - 0.17 11.6 0.1 0.25 11.0 0.1 1.2 1 0 0 1 1 1 0 Polyomavirus coat protein PhaP_Bmeg PF09602.10 AII58244.1 - 0.37 10.7 3.0 0.12 12.3 0.4 1.5 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Aldedh PF00171.22 AII58245.1 - 1.6e-21 76.4 6.1 7e-15 54.5 3.5 2.3 2 1 0 2 2 2 2 Aldehyde dehydrogenase family RNase_PH PF01138.21 AII58246.1 - 5.8e-20 72.1 0.1 9.4e-20 71.5 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 AII58246.1 - 6e-11 42.2 0.1 1.3e-10 41.2 0.1 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 NUDIX PF00293.28 AII58247.1 - 5.9e-08 32.8 0.1 7e-08 32.6 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain DUF3727 PF12527.8 AII58247.1 - 0.092 13.0 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3727) CinA PF02464.17 AII58248.1 - 7.2e-50 168.6 0.1 8.1e-50 168.4 0.1 1.0 1 0 0 1 1 1 1 Competence-damaged protein DUF167 PF02594.16 AII58249.1 - 2.3e-20 72.5 0.0 3e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 PreAtp-grasp PF18604.1 AII58249.1 - 0.13 11.9 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Pre ATP-grasp domain Response_reg PF00072.24 AII58250.1 - 5.6e-28 97.3 0.1 7.5e-28 96.9 0.1 1.2 1 0 0 1 1 1 1 Response regulator receiver domain HTH_17 PF12728.7 AII58250.1 - 1.3e-17 63.7 0.2 2.5e-17 62.8 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AII58250.1 - 0.00013 21.7 0.0 0.00035 20.3 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.6 AII58250.1 - 0.001 18.7 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 AII58250.1 - 0.0089 16.1 0.8 0.021 14.9 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain Methyltransf_24 PF13578.6 AII58250.1 - 0.014 16.4 0.0 0.024 15.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain HTH_Tnp_ISL3 PF13542.6 AII58250.1 - 0.021 14.2 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_22 PF13309.6 AII58250.1 - 0.023 14.7 0.1 0.064 13.3 0.1 1.8 1 0 0 1 1 1 0 HTH domain Sigma70_r4_2 PF08281.12 AII58250.1 - 0.054 13.2 0.3 0.24 11.1 0.1 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_Tnp_IS630 PF01710.16 AII58250.1 - 0.057 13.5 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Transposase DUF3906 PF13046.6 AII58250.1 - 0.072 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3906) TrmB PF01978.19 AII58250.1 - 0.074 12.9 0.1 0.23 11.4 0.1 1.8 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB MerR PF00376.23 AII58250.1 - 0.077 12.8 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 MerR family regulatory protein TetR_N PF00440.23 AII58250.1 - 0.094 12.5 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family ANT PF03374.14 AII58250.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain PAF-AH_p_II PF03403.13 AII58251.1 - 2.3e-08 32.9 0.0 8e-06 24.6 0.0 2.1 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_1 PF00561.20 AII58251.1 - 7.3e-06 25.8 1.2 0.0014 18.3 0.0 3.1 2 1 1 3 3 3 2 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 AII58251.1 - 4.1e-05 22.6 0.0 0.12 11.2 0.0 2.4 2 0 0 2 2 2 2 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 AII58251.1 - 6.2e-05 22.8 0.0 0.00017 21.4 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.14 AII58251.1 - 0.0015 18.1 0.0 0.5 9.8 0.0 2.2 2 0 0 2 2 2 2 Putative serine esterase (DUF676) Peptidase_S9 PF00326.21 AII58251.1 - 0.0051 16.3 0.1 0.034 13.6 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 AII58251.1 - 0.035 13.7 0.0 4.8 6.7 0.0 2.5 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 AII58251.1 - 0.047 14.3 0.0 0.064 13.9 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AII58251.1 - 0.12 11.6 0.2 0.58 9.4 0.2 1.9 1 1 1 2 2 2 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 AII58251.1 - 0.18 11.5 0.3 0.78 9.4 0.1 1.7 1 1 0 2 2 2 0 PGAP1-like protein zf-trcl PF13451.6 AII58252.1 - 2.2e-21 75.5 4.1 2.2e-21 75.5 4.1 2.8 3 0 0 3 3 3 1 Probable zinc-ribbon domain DZR PF12773.7 AII58252.1 - 0.00033 20.6 10.1 0.023 14.7 1.0 2.5 2 1 0 2 2 2 2 Double zinc ribbon DNA_RNApol_7kD PF03604.13 AII58252.1 - 0.0091 15.7 9.6 0.11 12.2 1.2 3.3 3 1 0 3 3 3 2 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.19 AII58252.1 - 0.028 14.4 6.6 0.4 10.7 0.7 2.1 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Lar_restr_allev PF14354.6 AII58252.1 - 0.09 13.2 12.0 0.3 11.5 0.3 2.8 1 1 2 3 3 3 0 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.10 AII58252.1 - 0.13 12.4 12.6 1.1 9.5 2.6 2.7 2 2 0 2 2 2 0 Zinc ribbon domain Cytochrom_CIII PF02085.16 AII58252.1 - 0.16 12.4 3.2 1.1 9.7 2.1 2.1 1 1 1 2 2 2 0 Class III cytochrome C family TSP9 PF11493.8 AII58252.1 - 0.16 12.7 0.2 0.22 12.2 0.2 1.2 1 0 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 CpXC PF14353.6 AII58252.1 - 0.46 10.5 7.6 2.8 8.0 0.1 2.7 2 2 0 2 2 2 0 CpXC protein Jiv90 PF14901.6 AII58252.1 - 0.55 10.4 5.5 0.3 11.2 0.5 2.2 2 1 0 2 2 2 0 Cleavage inducing molecular chaperone zinc_ribbon_6 PF14599.6 AII58252.1 - 0.62 10.1 8.2 3 7.9 0.7 2.8 3 1 0 3 3 3 0 Zinc-ribbon zf-C2H2_11 PF16622.5 AII58252.1 - 0.62 9.9 0.1 0.62 9.9 0.1 3.0 4 0 0 4 4 3 0 zinc-finger C2H2-type zinc_ribbon_4 PF13717.6 AII58252.1 - 0.63 10.0 13.7 1.7 8.6 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain LIM PF00412.22 AII58252.1 - 0.7 10.2 7.4 2 8.7 0.6 2.8 3 0 0 3 3 3 0 LIM domain zinc_ribbon_5 PF13719.6 AII58252.1 - 1 9.2 0.1 1 9.2 0.1 3.3 4 0 0 4 4 4 0 zinc-ribbon domain Zn_ribbon_SprT PF17283.2 AII58252.1 - 1.5 8.8 11.8 3.3 7.7 2.0 3.5 3 1 0 3 3 3 0 SprT-like zinc ribbon domain zf_UBZ PF18439.1 AII58252.1 - 1.5 8.4 5.9 5.2 6.7 0.1 2.9 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Auto_anti-p27 PF06677.12 AII58252.1 - 1.7 8.9 7.5 2.5 8.3 0.8 3.1 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF2318 PF10080.9 AII58252.1 - 3.1 7.9 8.3 6.5 6.9 1.0 2.8 1 1 2 3 3 3 0 Predicted membrane protein (DUF2318) zinc_ribbon_2 PF13240.6 AII58252.1 - 5.9 6.8 12.0 12 5.8 0.1 3.7 4 0 0 4 4 4 0 zinc-ribbon domain Cys_rich_CPXG PF14255.6 AII58252.1 - 5.9 6.9 8.3 6.6 6.7 1.9 2.3 2 1 0 2 2 2 0 Cysteine-rich CPXCG Zn_ribbon_recom PF13408.6 AII58252.1 - 7.1 7.2 12.8 0.5 10.9 0.9 2.5 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain OrfB_Zn_ribbon PF07282.11 AII58252.1 - 9.2 6.3 10.3 0.89 9.5 1.4 2.7 2 1 0 3 3 3 0 Putative transposase DNA-binding domain GTP_EFTU PF00009.27 AII58253.1 - 3.8e-51 173.4 0.0 6e-51 172.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 AII58253.1 - 2.6e-22 78.6 0.0 6.1e-22 77.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 AII58253.1 - 1.4e-11 44.6 0.4 3.9e-11 43.2 0.4 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AII58253.1 - 4.4e-06 26.8 0.1 1.1e-05 25.5 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 AII58253.1 - 5e-05 23.3 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II Roc PF08477.13 AII58253.1 - 0.0023 18.1 0.0 0.005 17.1 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 AII58253.1 - 0.0023 17.5 0.1 0.0073 15.9 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B Septin PF00735.18 AII58253.1 - 0.0054 16.1 0.1 0.011 15.0 0.1 1.4 1 0 0 1 1 1 1 Septin Ras PF00071.22 AII58253.1 - 0.0068 16.0 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 Ras family AIG1 PF04548.16 AII58253.1 - 0.032 13.6 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 AIG1 family RsgA_GTPase PF03193.16 AII58253.1 - 0.049 13.5 0.1 0.77 9.6 0.0 2.5 2 1 0 2 2 2 0 RsgA GTPase Arf PF00025.21 AII58253.1 - 0.085 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family DUF4347 PF14252.6 AII58253.1 - 0.12 12.2 0.0 1.8 8.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4347) Sugar_tr PF00083.24 AII58254.1 - 7.8e-35 120.6 31.9 2.8e-25 89.1 9.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 AII58254.1 - 1.2e-33 116.5 65.6 3.1e-27 95.4 38.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 AII58254.1 - 5.4 5.2 6.6 9.3 4.4 6.6 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Usp PF00582.26 AII58255.1 - 3.4e-29 102.2 0.6 3.9e-29 102.0 0.6 1.0 1 0 0 1 1 1 1 Universal stress protein family B12-binding PF02310.19 AII58255.1 - 0.034 14.2 0.1 0.042 13.9 0.1 1.2 1 0 0 1 1 1 0 B12 binding domain DUF502 PF04367.13 AII58256.1 - 3.7e-26 91.1 0.2 3.7e-26 91.1 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF502) MgtE PF01769.16 AII58256.1 - 0.1 13.0 4.0 0.15 12.5 4.0 1.2 1 0 0 1 1 1 0 Divalent cation transporter Nucleos_tra2_C PF07662.13 AII58256.1 - 0.12 12.2 1.5 0.17 11.7 1.5 1.3 1 0 0 1 1 1 0 Na+ dependent nucleoside transporter C-terminus Fasciclin PF02469.22 AII58257.1 - 9.5e-30 103.4 0.0 1.1e-29 103.2 0.0 1.0 1 0 0 1 1 1 1 Fasciclin domain Glyco_trans_4_2 PF13477.6 AII58258.1 - 5.5e-23 81.5 0.2 6.8e-23 81.2 0.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_transf_4 PF13439.6 AII58258.1 - 1.8e-08 34.6 0.1 2.4e-08 34.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 AII58258.1 - 0.00031 21.2 0.0 0.00067 20.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain DUF3481 PF11980.8 AII58258.1 - 0.2 11.4 0.5 0.4 10.4 0.2 1.6 2 0 0 2 2 2 0 C-terminal domain of neuropilin glycoprotein Rubrerythrin PF02915.17 AII58260.1 - 0.00021 21.7 1.3 0.00068 20.1 1.3 1.9 1 1 0 1 1 1 1 Rubrerythrin DUF1508 PF07411.12 AII58261.1 - 4.6e-24 84.0 0.1 5.2e-24 83.8 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1508) Abhydrolase_1 PF00561.20 AII58262.1 - 3.9e-22 79.1 0.0 9.4e-22 77.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 AII58262.1 - 8.1e-19 69.1 0.0 1.1e-18 68.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 AII58262.1 - 2.5e-11 43.3 0.3 2.2e-10 40.2 0.3 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 AII58262.1 - 5.8e-06 25.2 0.0 1.1e-05 24.3 0.0 1.3 1 1 0 1 1 1 1 Ndr family Abhydrolase_3 PF07859.13 AII58262.1 - 0.00012 22.0 0.0 0.0044 16.9 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 AII58262.1 - 0.0004 20.1 0.0 0.00054 19.7 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 AII58262.1 - 0.0036 16.8 0.0 0.05 13.1 0.0 2.4 2 1 0 2 2 2 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 AII58262.1 - 0.015 14.2 0.0 0.029 13.3 0.0 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme BAAT_C PF08840.11 AII58262.1 - 0.029 14.3 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal UPF0227 PF05728.12 AII58262.1 - 0.078 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) MgsA_C PF12002.8 AII58263.1 - 2e-70 236.1 0.0 3.1e-70 235.4 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 AII58263.1 - 1.7e-24 86.0 0.1 4.4e-24 84.6 0.0 1.8 2 0 0 2 2 1 1 AAA C-terminal domain AAA PF00004.29 AII58263.1 - 1.2e-15 58.1 0.0 2.3e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 AII58263.1 - 2.2e-15 56.7 0.0 3.7e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 AII58263.1 - 2.9e-08 33.8 0.0 5.5e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 AII58263.1 - 3.9e-07 29.7 0.3 0.0024 17.3 0.0 2.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 AII58263.1 - 9e-07 29.4 0.1 0.0014 19.0 0.0 2.6 1 1 1 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 AII58263.1 - 2.5e-06 27.5 0.1 0.0001 22.3 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 AII58263.1 - 4.6e-05 23.7 0.1 0.018 15.3 0.0 2.5 1 1 1 2 2 2 1 AAA domain Sigma54_activat PF00158.26 AII58263.1 - 8.9e-05 22.2 0.0 0.0091 15.7 0.0 2.3 1 1 1 2 2 2 1 Sigma-54 interaction domain ResIII PF04851.15 AII58263.1 - 0.00023 21.2 0.0 0.26 11.3 0.0 2.3 1 1 1 2 2 2 2 Type III restriction enzyme, res subunit AAA_18 PF13238.6 AII58263.1 - 0.00072 20.1 0.0 0.0015 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 AII58263.1 - 0.0011 18.9 0.0 0.0021 17.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AII58263.1 - 0.0022 17.8 0.0 0.037 13.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 AII58263.1 - 0.0023 18.0 0.0 0.0052 16.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain ATPase_2 PF01637.18 AII58263.1 - 0.0042 17.0 0.0 1.9 8.4 0.0 2.4 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea AAA_2 PF07724.14 AII58263.1 - 0.0043 17.2 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 AII58263.1 - 0.0046 17.1 0.0 0.0086 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 AII58263.1 - 0.0057 17.0 0.0 0.014 15.8 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_17 PF13207.6 AII58263.1 - 0.0095 16.4 0.0 0.056 13.9 0.0 1.9 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 AII58263.1 - 0.01 15.6 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.6 AII58263.1 - 0.011 16.0 0.0 0.13 12.6 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.6 AII58263.1 - 0.016 15.4 0.0 0.11 12.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 AII58263.1 - 0.019 15.5 0.0 0.058 13.9 0.0 1.6 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 AII58263.1 - 0.039 13.9 0.1 0.43 10.5 0.0 2.2 2 0 0 2 2 2 0 NACHT domain CPT PF07931.12 AII58263.1 - 0.047 13.5 0.0 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 AII58263.1 - 0.049 12.9 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Viral_helicase1 PF01443.18 AII58263.1 - 0.071 12.8 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Cytidylate_kin PF02224.18 AII58263.1 - 0.093 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase T2SSE PF00437.20 AII58263.1 - 0.1 11.6 0.0 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein TIP49 PF06068.13 AII58263.1 - 0.14 11.3 0.0 0.53 9.4 0.0 1.8 1 1 1 2 2 2 0 TIP49 P-loop domain AAA_24 PF13479.6 AII58263.1 - 0.14 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 AII58263.1 - 0.16 11.9 0.0 0.56 10.1 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase NB-ARC PF00931.22 AII58263.1 - 0.21 10.8 0.0 0.37 9.9 0.0 1.4 1 1 0 1 1 1 0 NB-ARC domain Gtr1_RagA PF04670.12 AII58263.1 - 0.21 10.9 0.0 14 4.9 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Memo PF01875.17 AII58266.1 - 1.9e-72 243.7 0.4 2.6e-72 243.2 0.4 1.2 1 0 0 1 1 1 1 Memo-like protein AMMECR1 PF01871.17 AII58266.1 - 5.7e-39 133.4 0.0 1.1e-38 132.5 0.0 1.5 1 0 0 1 1 1 1 AMMECR1 LigB PF02900.18 AII58266.1 - 0.0022 17.1 0.2 0.0036 16.4 0.2 1.4 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Beta-Casp PF10996.8 AII58266.1 - 0.094 13.0 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 Beta-Casp domain Radical_SAM PF04055.21 AII58267.1 - 7.2e-16 59.0 0.0 1.2e-15 58.2 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AII58267.1 - 2.5e-05 24.5 0.1 7.5e-05 23.0 0.1 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain EamA PF00892.20 AII58268.1 - 2.6e-17 63.3 40.7 1.7e-10 41.2 15.6 3.1 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 AII58268.1 - 5.8e-06 25.9 14.9 0.00021 20.7 1.9 2.7 2 1 1 3 3 3 2 Triose-phosphate Transporter family DUF520 PF04461.13 AII58270.1 - 2.5e-54 183.7 8.6 2.9e-54 183.6 8.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF520) DUF4638 PF15472.6 AII58270.1 - 0.0064 16.3 1.0 0.0073 16.1 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4638) YcxB PF14317.6 AII58271.1 - 2.6e-06 27.0 0.1 7.3e-06 25.6 0.1 1.8 2 0 0 2 2 2 1 YcxB-like protein FeoB_associated PF12669.7 AII58271.1 - 2.4 8.6 4.3 1.4 9.4 0.7 2.2 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein AAA_21 PF13304.6 AII58272.1 - 3.5e-15 56.6 0.1 2.8e-07 30.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AII58272.1 - 3.8e-15 56.5 0.0 5.2e-07 29.7 0.1 2.1 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 AII58272.1 - 7.4e-09 35.4 0.0 0.0019 17.7 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 AII58272.1 - 1.8e-07 31.8 0.0 2.8e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 AII58272.1 - 3.1e-05 24.5 0.0 4.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 AII58272.1 - 6e-05 22.7 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 AII58272.1 - 0.00024 21.3 0.0 0.00035 20.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AII58272.1 - 0.00077 19.9 0.0 0.0012 19.2 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 AII58272.1 - 0.0018 18.3 0.0 0.0034 17.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 AII58272.1 - 0.0053 17.0 0.0 0.018 15.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 AII58272.1 - 0.0061 16.5 0.0 0.015 15.2 0.0 1.6 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 AII58272.1 - 0.01 16.3 0.0 0.018 15.5 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 AII58272.1 - 0.014 15.7 0.0 0.06 13.7 0.0 2.0 2 0 0 2 2 2 0 RNA helicase RsgA_GTPase PF03193.16 AII58272.1 - 0.018 14.9 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase ABC_ATPase PF09818.9 AII58272.1 - 0.11 11.3 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Predicted ATPase of the ABC class DUF220 PF02713.14 AII58272.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF220 cobW PF02492.19 AII58272.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 AII58272.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MukB PF04310.12 AII58272.1 - 0.18 11.6 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 MukB N-terminal AAA_28 PF13521.6 AII58272.1 - 0.22 11.8 0.0 1 9.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 AII58272.1 - 0.24 11.1 0.0 7.7 6.2 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain FMN_red PF03358.15 AII58273.1 - 8e-29 100.4 0.0 1e-28 100.1 0.0 1.0 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 AII58273.1 - 3e-11 43.4 0.0 6.9e-10 39.0 0.0 2.0 2 0 0 2 2 2 1 Flavodoxin-like fold Flavodoxin_5 PF12724.7 AII58273.1 - 0.0019 18.4 0.0 0.063 13.5 0.0 2.2 2 0 0 2 2 2 1 Flavodoxin domain Acetyltransf_1 PF00583.25 AII58274.1 - 2.5e-05 24.5 0.0 4.1e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 AII58274.1 - 0.012 15.7 0.0 0.023 14.8 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AII58274.1 - 0.012 16.0 0.0 0.047 14.1 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Gly_acyl_tr_C PF08444.10 AII58274.1 - 0.14 12.4 0.0 0.41 10.9 0.0 1.8 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region DUF3500 PF12006.8 AII58275.1 - 0.093 12.2 0.0 0.096 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) 14-3-3 PF00244.20 AII58275.1 - 0.1 12.1 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 14-3-3 protein CoaE PF01121.20 AII58276.1 - 3.3e-51 173.5 0.0 3.8e-51 173.3 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 AII58276.1 - 4.4e-08 33.7 0.3 1.1e-07 32.5 0.3 1.7 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 AII58276.1 - 1.7e-06 28.3 0.2 8.8e-06 26.0 0.2 1.9 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_28 PF13521.6 AII58276.1 - 5.6e-05 23.4 0.1 0.00013 22.2 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 AII58276.1 - 0.00033 20.8 0.0 0.00087 19.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 AII58276.1 - 0.0016 18.9 0.1 0.083 13.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain Hydant_A_N PF05378.13 AII58276.1 - 0.0019 17.9 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region AAA_22 PF13401.6 AII58276.1 - 0.0094 16.2 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 AII58276.1 - 0.026 14.7 0.2 0.2 11.8 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase ABC_tran PF00005.27 AII58276.1 - 0.047 14.2 0.1 0.055 14.0 0.1 1.4 1 1 0 1 1 1 0 ABC transporter PRK PF00485.18 AII58276.1 - 0.12 12.1 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family PduV-EutP PF10662.9 AII58276.1 - 0.13 12.0 0.1 0.24 11.2 0.1 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation dNK PF01712.19 AII58276.1 - 0.17 11.7 0.4 0.42 10.4 0.1 1.8 2 0 0 2 2 2 0 Deoxynucleoside kinase NTPase_1 PF03266.15 AII58276.1 - 0.31 10.9 2.4 1.1 9.1 1.1 2.2 1 1 1 2 2 2 0 NTPase NAD_binding_10 PF13460.6 AII58277.1 - 5.1e-22 78.6 0.0 8.5e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 AII58277.1 - 2.5e-21 76.2 0.0 3.5e-20 72.5 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AII58277.1 - 1.5e-17 63.6 0.0 2.1e-14 53.2 0.0 2.2 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 AII58277.1 - 2.2e-17 63.4 0.0 2.7e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 AII58277.1 - 3.8e-08 33.1 0.0 1.1e-06 28.3 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 AII58277.1 - 1.9e-07 30.5 2.2 0.096 11.8 0.1 3.1 2 1 0 3 3 3 3 Male sterility protein RmlD_sub_bind PF04321.17 AII58277.1 - 9.8e-07 28.2 0.1 0.005 16.0 0.0 2.7 2 1 0 2 2 2 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 AII58277.1 - 6.3e-06 25.5 0.1 1.2e-05 24.6 0.1 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 AII58277.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Ribosomal_L21p PF00829.21 AII58278.1 - 5.3e-35 119.7 0.1 6.7e-35 119.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Ribosomal_L27 PF01016.19 AII58279.1 - 8e-38 128.3 1.3 9e-38 128.2 1.3 1.0 1 0 0 1 1 1 1 Ribosomal L27 protein DUF3253 PF11625.8 AII58279.1 - 0.013 15.7 0.1 0.018 15.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) Ribosomal_L31 PF01197.18 AII58280.1 - 4.3e-30 103.7 0.8 4.8e-30 103.6 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L31 DUF3039 PF11238.8 AII58280.1 - 0.0033 17.1 0.3 0.0044 16.7 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3039) DUF1385 PF07136.11 AII58281.1 - 4.3e-78 261.7 9.1 5.2e-78 261.5 9.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1385) PRA-CH PF01502.18 AII58282.1 - 7e-33 112.3 0.1 9e-33 111.9 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase Acetyltransf_1 PF00583.25 AII58283.1 - 1.2e-12 48.0 0.1 1.4e-12 47.8 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 AII58283.1 - 9.2e-07 28.8 0.0 1.2e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 AII58283.1 - 5.5e-06 27.1 0.2 6.3e-06 26.9 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AII58283.1 - 4.7e-05 23.7 0.0 7.5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AII58283.1 - 0.00096 19.1 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 AII58283.1 - 0.015 15.4 0.0 0.025 14.6 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 AII58283.1 - 0.021 15.0 0.0 0.048 13.8 0.0 1.7 1 1 1 2 2 2 0 GCN5-related N-acetyl-transferase His_biosynth PF00977.21 AII58284.1 - 1.2e-82 276.8 0.2 1.3e-82 276.7 0.2 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.17 AII58284.1 - 5e-11 42.3 0.0 0.00012 21.3 0.0 2.1 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.14 AII58284.1 - 2.1e-06 27.1 0.1 0.021 14.0 0.0 2.1 1 1 1 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase TMP-TENI PF02581.17 AII58284.1 - 7.2e-06 25.4 0.3 0.096 12.0 0.1 2.3 2 0 0 2 2 2 2 Thiamine monophosphate synthase Trp_syntA PF00290.20 AII58284.1 - 1.1e-05 24.4 0.6 0.008 15.0 0.1 2.3 2 1 0 2 2 2 2 Tryptophan synthase alpha chain ThiG PF05690.14 AII58284.1 - 4.7e-05 22.8 2.3 0.059 12.7 0.3 2.1 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG NMO PF03060.15 AII58284.1 - 0.00011 21.7 2.6 0.064 12.6 0.1 2.1 1 1 0 2 2 2 2 Nitronate monooxygenase PcrB PF01884.17 AII58284.1 - 0.0011 18.4 0.4 0.011 15.2 0.1 2.0 1 1 0 2 2 2 1 PcrB family IMPDH PF00478.25 AII58284.1 - 0.0039 16.3 1.1 0.18 10.7 0.1 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain IGPS PF00218.21 AII58284.1 - 0.0047 16.1 0.0 0.97 8.5 0.0 2.2 2 0 0 2 2 2 2 Indole-3-glycerol phosphate synthase G3P_antiterm PF04309.12 AII58284.1 - 0.0061 16.0 0.7 0.27 10.6 0.1 2.6 3 0 0 3 3 3 1 Glycerol-3-phosphate responsive antiterminator BtpA PF03437.15 AII58284.1 - 0.0065 15.9 0.9 1.3 8.3 0.1 2.7 1 1 1 3 3 3 1 BtpA family DHO_dh PF01180.21 AII58284.1 - 0.0069 15.6 0.1 1 8.5 0.0 2.1 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase DUF561 PF04481.12 AII58284.1 - 0.0074 15.5 0.1 0.017 14.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF561) DUF2399 PF09664.10 AII58284.1 - 0.014 15.3 0.1 5.2 7.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2399) DeoC PF01791.9 AII58284.1 - 0.017 14.8 0.1 0.035 13.7 0.0 1.7 2 0 0 2 2 2 0 DeoC/LacD family aldolase DUF3955 PF13127.6 AII58284.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3955) B12-binding PF02310.19 AII58284.1 - 0.073 13.1 0.4 4.6 7.3 0.1 2.6 2 1 1 3 3 3 0 B12 binding domain Ribul_P_3_epim PF00834.19 AII58284.1 - 0.14 11.6 0.2 0.47 9.8 0.1 1.8 2 0 0 2 2 2 0 Ribulose-phosphate 3 epimerase family DUF2769 PF10967.8 AII58285.1 - 3.5e-13 50.0 12.4 4.2e-13 49.7 12.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2769) Cys_rich_CWC PF14375.6 AII58285.1 - 0.1 13.0 6.5 3.5 8.1 1.6 2.3 2 0 0 2 2 2 0 Cysteine-rich CWC NfeD PF01957.18 AII58286.1 - 3.5e-16 59.3 1.1 4.8e-16 58.9 1.1 1.2 1 0 0 1 1 1 1 NfeD-like C-terminal, partner-binding Glu-tRNAGln PF02686.15 AII58287.1 - 5.8e-20 71.3 0.2 8.6e-20 70.8 0.2 1.3 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit Amidase PF01425.21 AII58288.1 - 3.4e-161 537.2 0.0 3.8e-161 537.0 0.0 1.0 1 0 0 1 1 1 1 Amidase DUF3482 PF11981.8 AII58289.1 - 1.2 8.5 6.0 2.1 7.7 6.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Gly-zipper_YMGG PF13441.6 AII58289.1 - 2.7 7.8 7.3 6.7 6.5 7.3 1.6 1 1 0 1 1 1 0 YMGG-like Gly-zipper DUF2178 PF09946.9 AII58290.1 - 1.9e-20 73.0 1.3 2.3e-20 72.7 1.3 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2178) UPF0093 PF03653.13 AII58290.1 - 0.05 13.8 0.8 0.66 10.2 0.0 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0093) Phage_holin_2_1 PF04971.12 AII58290.1 - 0.58 10.2 4.7 1.6 8.8 0.1 2.3 2 0 0 2 2 2 0 Bacteriophage P21 holin S DUF2070 PF09843.9 AII58290.1 - 1.1 7.5 4.1 1.2 7.4 4.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF983 PF06170.12 AII58290.1 - 5.1 7.6 7.4 9.6 6.7 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF983) HTH_3 PF01381.22 AII58291.1 - 4.9e-17 61.7 0.2 5.5e-17 61.6 0.2 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 AII58291.1 - 1.6e-10 40.9 0.3 1.7e-10 40.7 0.3 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 AII58291.1 - 9.4e-08 32.3 0.0 1.1e-07 32.1 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AII58291.1 - 1.2e-06 28.8 0.0 1.4e-06 28.6 0.0 1.0 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain Sigma70_r4 PF04545.16 AII58291.1 - 1e-05 25.0 0.1 1.9e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_11 PF08279.12 AII58291.1 - 9.1e-05 22.3 0.2 0.00013 21.8 0.2 1.3 1 0 0 1 1 1 1 HTH domain HTH_Crp_2 PF13545.6 AII58291.1 - 0.00015 21.7 0.0 0.00048 20.0 0.0 1.7 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_23 PF13384.6 AII58291.1 - 0.00025 20.8 0.0 0.00036 20.3 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_24 PF13412.6 AII58291.1 - 0.00045 19.7 0.1 0.00071 19.1 0.1 1.4 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding Phage_CI_repr PF07022.13 AII58291.1 - 0.0023 18.0 0.0 0.0026 17.8 0.0 1.1 1 0 0 1 1 1 1 Bacteriophage CI repressor helix-turn-helix domain HTH_25 PF13413.6 AII58291.1 - 0.0032 17.3 0.1 0.0041 16.9 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 AII58291.1 - 0.0034 17.0 0.0 0.0062 16.2 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 YdaS_antitoxin PF15943.5 AII58291.1 - 0.007 16.2 0.0 0.0078 16.1 0.0 1.2 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT MarR PF01047.22 AII58291.1 - 0.032 14.2 0.1 0.059 13.3 0.1 1.4 1 0 0 1 1 1 0 MarR family MarR_2 PF12802.7 AII58291.1 - 0.033 14.1 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_37 PF13744.6 AII58291.1 - 0.041 13.8 0.0 0.051 13.5 0.0 1.3 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_17 PF12728.7 AII58291.1 - 0.042 14.0 0.0 0.067 13.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 AII58291.1 - 0.075 12.9 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain GntR PF00392.21 AII58291.1 - 0.093 12.4 0.0 0.18 11.5 0.0 1.5 1 1 1 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_28 PF13518.6 AII58291.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain ABC_tran PF00005.27 AII58292.1 - 7.2e-31 107.5 0.0 6.5e-30 104.4 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 AII58292.1 - 2.5e-17 63.7 1.7 3.9e-12 46.6 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 AII58292.1 - 6e-06 26.2 0.0 0.024 14.4 0.0 2.2 1 1 0 2 2 2 2 AAA ATPase domain DUF4162 PF13732.6 AII58292.1 - 0.00026 21.6 0.1 0.0006 20.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) AAA_23 PF13476.6 AII58292.1 - 0.00037 21.1 2.6 0.00082 19.9 2.6 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 AII58292.1 - 0.0099 16.3 0.1 0.076 13.4 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 AII58292.1 - 0.03 14.2 0.0 0.088 12.7 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_29 PF13555.6 AII58292.1 - 0.043 13.6 0.2 0.087 12.6 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 AII58292.1 - 0.061 13.6 0.1 0.4 11.0 0.1 2.2 1 1 0 1 1 1 0 AAA domain ABC2_membrane_2 PF12679.7 AII58293.1 - 3e-08 33.3 16.6 1.1e-05 24.9 16.6 2.7 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 AII58293.1 - 0.0022 17.1 26.5 0.0066 15.6 26.6 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 AII58293.1 - 0.057 13.4 17.4 0.046 13.7 14.8 1.9 1 1 0 1 1 1 0 ABC-2 family transporter protein ABC2_membrane_5 PF13346.6 AII58293.1 - 0.11 12.0 22.6 0.22 11.0 22.6 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein Phage_holin_2_1 PF04971.12 AII58293.1 - 0.17 11.9 2.4 0.25 11.4 0.5 2.2 2 0 0 2 2 2 0 Bacteriophage P21 holin S Phage_holin_Dp1 PF16938.5 AII58293.1 - 0.6 10.4 5.7 2.7 8.3 0.0 3.2 3 0 0 3 3 3 0 Putative phage holin Dp-1 AsnC_trans_reg PF01037.21 AII58294.1 - 1e-14 54.2 0.0 1.4e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_AsnC-type PF13404.6 AII58294.1 - 0.0042 16.9 0.1 0.0097 15.7 0.0 1.6 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 AII58294.1 - 0.0097 15.5 0.1 0.022 14.3 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding PRT_C PF08372.10 AII58294.1 - 0.012 15.4 0.0 0.015 15.1 0.0 1.1 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal AsnC_trans_reg2 PF17805.1 AII58294.1 - 0.077 13.2 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 AsnC-like ligand binding domain Aminotran_1_2 PF00155.21 AII58295.1 - 1.3e-65 222.0 0.0 1.4e-65 221.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 AII58295.1 - 1.1e-06 27.9 0.0 1.8e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 AII58295.1 - 2e-06 27.4 0.0 3.2e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 AII58295.1 - 0.00017 20.2 0.0 0.0003 19.4 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 AII58295.1 - 0.002 17.4 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase tRNA-synt_1b PF00579.25 AII58296.1 - 1.8e-67 227.7 0.0 2.1e-67 227.5 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) LYTB PF02401.18 AII58297.1 - 6.7e-79 264.9 0.0 7.5e-79 264.7 0.0 1.0 1 0 0 1 1 1 1 LytB protein Vip3A_N PF12495.8 AII58297.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal DeoC PF01791.9 AII58298.1 - 4.3e-35 121.4 0.0 5.1e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase DUF2090 PF09863.9 AII58298.1 - 0.0029 16.7 0.0 0.016 14.3 0.0 2.2 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2090) PfkB PF00294.24 AII58299.1 - 2e-48 165.2 0.0 2.3e-48 165.1 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 AII58299.1 - 6.5e-11 42.1 0.2 9e-11 41.6 0.2 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Sigma70_r2 PF04542.14 AII58301.1 - 1.4e-18 66.4 0.2 2.1e-18 65.8 0.2 1.3 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 AII58301.1 - 4.9e-10 38.8 0.0 9.9e-10 37.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AII58301.1 - 1.7e-08 34.5 0.1 3e-08 33.8 0.1 1.4 1 1 0 1 1 1 1 ECF sigma factor Sigma70_r4_2 PF08281.12 AII58301.1 - 1.4e-05 24.7 0.0 2.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 COG2 PF06148.11 AII58301.1 - 0.001 19.1 0.2 0.0027 17.8 0.0 1.7 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 HTH_16 PF12645.7 AII58301.1 - 0.05 13.7 1.2 0.12 12.4 1.2 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.6 AII58301.1 - 0.08 12.7 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_17 PF12728.7 AII58302.1 - 6.9e-14 51.8 0.0 7.7e-14 51.6 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain MerR_1 PF13411.6 AII58302.1 - 5.4e-08 32.8 0.1 6.5e-08 32.6 0.1 1.1 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 AII58302.1 - 7.3e-05 22.5 0.0 0.00022 20.9 0.0 1.7 2 0 0 2 2 2 1 MerR family regulatory protein HTH_23 PF13384.6 AII58302.1 - 0.00063 19.5 0.2 0.00089 19.0 0.2 1.5 1 1 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 AII58302.1 - 0.0065 15.9 0.4 0.01 15.2 0.4 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.6 AII58302.1 - 0.013 15.6 0.6 0.032 14.2 0.3 1.8 1 1 1 2 2 2 0 Winged helix-turn helix DUF1580 PF07618.11 AII58302.1 - 0.017 14.7 0.4 0.027 14.1 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1580) DUF1323 PF07037.11 AII58302.1 - 0.021 15.2 0.5 0.43 11.0 0.1 2.0 1 1 1 2 2 2 0 Putative transcription regulator (DUF1323) GerE PF00196.19 AII58303.1 - 3.8e-22 77.6 0.9 5.6e-22 77.1 0.9 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Response_reg PF00072.24 AII58303.1 - 5e-16 58.9 0.0 1.1e-15 57.7 0.0 1.6 2 0 0 2 2 2 1 Response regulator receiver domain Sigma70_r4_2 PF08281.12 AII58303.1 - 6e-06 25.8 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AII58303.1 - 1.6e-05 24.3 0.0 3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_11 PF08279.12 AII58303.1 - 0.00074 19.4 0.4 0.0016 18.3 0.4 1.6 1 0 0 1 1 1 1 HTH domain HTH_40 PF14493.6 AII58303.1 - 0.00098 19.5 0.2 0.0035 17.8 0.1 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 AII58303.1 - 0.0052 16.5 0.1 0.012 15.4 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_7 PF02796.15 AII58303.1 - 0.0068 16.5 0.1 0.021 14.9 0.1 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 AII58303.1 - 0.0097 15.9 0.1 0.027 14.5 0.0 1.7 2 0 0 2 2 2 1 Winged helix-turn helix HTH_24 PF13412.6 AII58303.1 - 0.024 14.2 0.6 0.055 13.0 0.6 1.7 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_10 PF04967.12 AII58303.1 - 0.025 14.4 0.1 0.025 14.4 0.1 2.0 2 0 0 2 2 2 0 HTH DNA binding domain DUF2089 PF09862.9 AII58303.1 - 0.025 14.6 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) HTH_23 PF13384.6 AII58303.1 - 0.026 14.3 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain DUF1776 PF08643.10 AII58303.1 - 0.053 12.9 0.4 0.075 12.4 0.4 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) HTH_28 PF13518.6 AII58303.1 - 0.065 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_terminase PF10668.9 AII58303.1 - 0.071 13.1 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Phage terminase small subunit NUMOD1 PF07453.13 AII58303.1 - 0.18 12.1 0.3 2.9 8.2 0.1 2.3 2 0 0 2 2 2 0 NUMOD1 domain T2SSE PF00437.20 AII58304.1 - 3.5e-75 252.6 1.7 6.1e-75 251.8 1.7 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein T2SSE_N PF05157.15 AII58304.1 - 2e-12 47.3 0.0 4.8e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein E, N-terminal domain Mrr_cat PF04471.12 AII58304.1 - 1.7e-10 40.9 0.6 0.00081 19.4 0.1 2.5 2 0 0 2 2 2 2 Restriction endonuclease TK PF00265.18 AII58304.1 - 0.0026 17.6 0.4 0.017 15.0 0.4 2.2 1 1 0 1 1 1 1 Thymidine kinase Zeta_toxin PF06414.12 AII58304.1 - 0.0075 15.6 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 AII58304.1 - 0.011 16.1 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 AII58304.1 - 0.014 15.9 3.1 0.016 15.7 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 AII58304.1 - 0.044 13.8 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 AII58304.1 - 0.05 13.3 0.1 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 AII58304.1 - 0.072 13.6 0.0 0.22 12.0 0.0 1.8 1 0 0 1 1 1 0 ABC transporter T2SSF PF00482.23 AII58305.1 - 4.7e-53 178.4 8.9 3.2e-31 107.9 0.1 2.5 3 0 0 3 3 3 2 Type II secretion system (T2SS), protein F DUF2207 PF09972.9 AII58305.1 - 0.003 16.4 0.5 0.0083 14.9 0.2 1.7 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) PvlArgDC PF01862.16 AII58305.1 - 0.072 12.9 0.1 1.8 8.3 0.1 2.3 2 0 0 2 2 2 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) FtsX PF02687.21 AII58305.1 - 0.38 11.3 10.2 0.57 10.7 3.3 2.4 2 0 0 2 2 2 0 FtsX-like permease family TrbC PF04956.13 AII58305.1 - 0.77 10.0 6.0 4.3 7.6 0.6 3.1 3 0 0 3 3 3 0 TrbC/VIRB2 family Phage_holin_3_6 PF07332.11 AII58305.1 - 3.4 7.7 10.6 0.17 11.9 2.1 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III N_methyl PF07963.12 AII58306.1 - 2.2e-08 33.3 2.0 2.2e-08 33.3 2.0 1.7 2 0 0 2 2 2 1 Prokaryotic N-terminal methylation motif P22_portal PF16510.5 AII58306.1 - 0.058 12.0 0.1 0.072 11.7 0.1 1.0 1 0 0 1 1 1 0 Phage P22-like portal protein PGF-CTERM PF18204.1 AII58306.1 - 0.71 9.9 5.4 1.4 9.0 5.4 1.5 1 0 0 1 1 1 0 PGF-CTERM motif N_methyl PF07963.12 AII58307.1 - 2.8e-10 39.3 0.8 4.5e-10 38.6 0.8 1.4 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif Big_9 PF17963.1 AII58307.1 - 0.011 16.5 2.2 0.023 15.4 2.2 1.5 1 0 0 1 1 1 0 Bacterial Ig domain PilX_N PF14341.6 AII58308.1 - 0.12 12.3 9.1 5 7.2 9.1 3.2 1 1 0 1 1 1 0 PilX N-terminal UPF0242 PF06785.11 AII58310.1 - 0.0047 17.1 0.7 0.007 16.5 0.7 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF3692 PF12469.8 AII58310.1 - 0.11 12.7 0.0 3.7 7.8 0.0 2.2 2 0 0 2 2 2 0 CRISPR-associated protein Gram_pos_anchor PF00746.21 AII58310.1 - 0.12 12.3 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif PilM_2 PF11104.8 AII58311.1 - 2e-18 66.5 0.9 2.4e-17 63.0 0.9 2.2 2 0 0 2 2 2 1 Type IV pilus assembly protein PilM; AAA_13 PF13166.6 AII58311.1 - 0.0043 15.8 0.3 0.0067 15.1 0.3 1.2 1 0 0 1 1 1 1 AAA domain GDP_Man_Dehyd PF16363.5 AII58311.1 - 0.071 12.5 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase CC2-LZ PF16516.5 AII58311.1 - 0.16 12.3 1.0 0.31 11.4 1.0 1.4 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator T2SSE PF00437.20 AII58312.1 - 6.5e-40 136.9 0.1 1.1e-39 136.2 0.1 1.4 1 1 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 AII58312.1 - 5e-06 26.4 0.2 2.1e-05 24.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 AII58312.1 - 3.1e-05 24.3 0.1 0.00015 22.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 AII58312.1 - 0.00011 22.6 0.7 0.00084 19.7 0.8 2.2 2 1 0 2 2 1 1 AAA domain AAA_29 PF13555.6 AII58312.1 - 0.00023 20.9 0.0 0.00063 19.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 AII58312.1 - 0.0003 21.3 0.1 0.00081 19.9 0.0 1.8 2 0 0 2 2 1 1 ABC transporter DUF87 PF01935.17 AII58312.1 - 0.00036 20.7 0.0 0.00062 19.9 0.0 1.5 1 1 0 1 1 1 1 Helicase HerA, central domain Zeta_toxin PF06414.12 AII58312.1 - 0.0004 19.7 0.0 0.00099 18.4 0.0 1.6 1 1 0 1 1 1 1 Zeta toxin AAA_7 PF12775.7 AII58312.1 - 0.00069 19.2 1.0 0.0054 16.3 0.0 2.6 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_23 PF13476.6 AII58312.1 - 0.00073 20.1 0.0 0.0019 18.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AII58312.1 - 0.00096 19.6 0.0 0.0022 18.4 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 AII58312.1 - 0.0011 18.9 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea FtsK_SpoIIIE PF01580.18 AII58312.1 - 0.0015 17.9 0.1 0.0029 17.0 0.1 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_14 PF13173.6 AII58312.1 - 0.0021 18.1 0.0 0.0073 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 AII58312.1 - 0.0034 17.2 0.0 0.0065 16.3 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein DAP3 PF10236.9 AII58312.1 - 0.0038 16.4 0.1 0.0084 15.3 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 DEAD PF00270.29 AII58312.1 - 0.0051 16.6 0.0 0.01 15.6 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 AII58312.1 - 0.0064 16.5 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit NTPase_1 PF03266.15 AII58312.1 - 0.01 15.7 0.4 0.1 12.5 0.3 2.4 2 0 0 2 2 2 0 NTPase AAA_33 PF13671.6 AII58312.1 - 0.017 15.3 0.1 0.03 14.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 AII58312.1 - 0.018 14.7 0.1 0.06 13.0 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain TrwB_AAD_bind PF10412.9 AII58312.1 - 0.019 13.9 0.0 0.031 13.2 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_11 PF13086.6 AII58312.1 - 0.02 14.7 0.0 0.06 13.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain cobW PF02492.19 AII58312.1 - 0.023 14.3 0.1 0.046 13.3 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_27 PF13514.6 AII58312.1 - 0.025 14.1 0.0 0.14 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 AII58312.1 - 0.03 14.2 0.0 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 AII58312.1 - 0.038 14.1 0.0 0.075 13.1 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase CbiA PF01656.23 AII58312.1 - 0.039 14.0 0.1 0.079 13.0 0.1 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain KTI12 PF08433.10 AII58312.1 - 0.044 13.2 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 TK PF00265.18 AII58312.1 - 0.048 13.5 0.0 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 Thymidine kinase AAA_18 PF13238.6 AII58312.1 - 0.069 13.7 0.0 0.16 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 AII58312.1 - 0.07 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.9 AII58312.1 - 0.072 12.3 0.1 0.31 10.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 AII58312.1 - 0.077 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 AII58312.1 - 0.078 13.2 0.1 0.36 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain FTHFS PF01268.19 AII58312.1 - 0.079 11.1 0.0 0.15 10.2 0.0 1.3 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase SMC_N PF02463.19 AII58312.1 - 0.079 12.4 0.0 0.24 10.8 0.0 1.7 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain SWI2_SNF2 PF18766.1 AII58312.1 - 0.091 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 SWI2/SNF2 ATPase MeaB PF03308.16 AII58312.1 - 0.1 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Rad17 PF03215.15 AII58312.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain NTPase_P4 PF11602.8 AII58312.1 - 0.18 11.0 0.2 0.33 10.1 0.2 1.4 1 1 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 N_methyl PF07963.12 AII58313.1 - 2.5e-11 42.6 1.1 3.9e-11 42.0 1.1 1.3 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif DiS_P_DiS PF06750.13 AII58314.1 - 1.8e-27 95.2 0.6 3.9e-27 94.2 0.6 1.6 1 0 0 1 1 1 1 Bacterial Peptidase A24 N-terminal domain Peptidase_A24 PF01478.18 AII58314.1 - 1.1e-13 51.6 14.7 1.1e-13 51.6 14.7 2.6 3 0 0 3 3 3 1 Type IV leader peptidase family DZR PF12773.7 AII58314.1 - 0.041 13.9 0.1 0.066 13.2 0.1 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 AII58314.1 - 1.3 8.5 3.9 7.5 6.1 0.7 2.4 2 0 0 2 2 2 0 zinc-ribbon domain PgaD PF13994.6 AII58314.1 - 1.6 8.8 3.9 4.9 7.2 0.0 2.4 2 0 0 2 2 2 0 PgaD-like protein Osmo_MPGsynth PF09488.10 AII58315.1 - 3e-151 503.5 0.0 1.6e-150 501.2 0.0 1.8 2 0 0 2 2 2 1 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) Hydrolase_3 PF08282.12 AII58315.1 - 1e-15 58.2 0.2 3.8e-15 56.3 0.2 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 AII58315.1 - 3e-05 23.7 0.0 0.039 13.5 0.0 2.4 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase_6 PF13344.6 AII58315.1 - 0.067 13.3 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase RDD PF06271.12 AII58316.1 - 1e-25 90.6 10.5 1.2e-25 90.4 10.5 1.1 1 0 0 1 1 1 1 RDD family tRNA-synt_1c PF00749.21 AII58317.1 - 8.6e-106 353.4 0.0 1e-105 353.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain DUF3795 PF12675.7 AII58318.1 - 1.6e-05 25.2 13.6 0.00041 20.7 13.6 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3795) DUF3461 PF11944.8 AII58318.1 - 0.078 13.1 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) Radical_SAM PF04055.21 AII58320.1 - 9.2e-05 22.9 0.0 0.00016 22.1 0.0 1.5 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 AII58320.1 - 0.00055 20.2 0.2 0.001 19.4 0.2 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 AII58320.1 - 0.012 15.8 0.1 0.02 15.0 0.1 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain Kazal_2 PF07648.15 AII58320.1 - 5.5 7.2 9.7 0.64 10.2 2.9 2.3 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain UPF0054 PF02130.17 AII58322.1 - 1.2e-34 118.9 0.3 1.4e-34 118.6 0.3 1.0 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 FMN_red PF03358.15 AII58323.1 - 2.6e-24 85.7 0.0 3.2e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 AII58323.1 - 7.1e-12 45.4 0.0 8.5e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold CRAM_rpt PF07016.11 AII58323.1 - 0.17 11.7 2.1 0.3 10.9 2.1 1.4 1 0 0 1 1 1 0 Cysteine-rich acidic integral membrane protein precursor DHO_dh PF01180.21 AII58324.1 - 3.7e-75 252.9 0.2 4.7e-75 252.5 0.2 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Dus PF01207.17 AII58324.1 - 6.4e-12 45.2 0.9 6.5e-05 22.2 0.0 2.0 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NMO PF03060.15 AII58324.1 - 4.2e-08 32.9 7.8 2.8e-07 30.3 7.8 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 AII58324.1 - 7.6e-06 25.6 0.1 1.7e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 Histidine biosynthesis protein PcrB PF01884.17 AII58324.1 - 0.00082 18.9 0.2 1.3 8.4 0.1 2.3 2 0 0 2 2 2 2 PcrB family G3P_antiterm PF04309.12 AII58324.1 - 0.0028 17.1 0.4 0.0082 15.6 0.2 1.8 2 0 0 2 2 2 1 Glycerol-3-phosphate responsive antiterminator IMPDH PF00478.25 AII58324.1 - 0.0035 16.4 1.7 0.0038 16.3 0.7 1.5 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Rib_5-P_isom_A PF06026.14 AII58324.1 - 0.0035 16.9 0.0 0.012 15.2 0.0 1.8 2 0 0 2 2 2 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DUF561 PF04481.12 AII58324.1 - 0.0081 15.4 0.2 0.014 14.5 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF561) FMN_dh PF01070.18 AII58324.1 - 0.015 14.4 3.1 0.13 11.3 3.1 2.1 1 1 0 1 1 1 0 FMN-dependent dehydrogenase Glu_synthase PF01645.17 AII58324.1 - 0.017 14.3 2.9 0.043 13.0 2.7 1.7 1 1 0 1 1 1 0 Conserved region in glutamate synthase AsnC_trans_reg PF01037.21 AII58324.1 - 0.033 14.1 0.0 0.088 12.8 0.0 1.7 1 0 0 1 1 1 0 Lrp/AsnC ligand binding domain Trp_syntA PF00290.20 AII58324.1 - 0.086 11.7 0.7 1.6 7.5 0.2 2.1 2 0 0 2 2 2 0 Tryptophan synthase alpha chain HMGL-like PF00682.19 AII58324.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 HMGL-like zf-dskA_traR PF01258.17 AII58325.1 - 1.5e-11 44.1 1.6 2.9e-11 43.1 1.6 1.6 1 0 0 1 1 1 1 Prokaryotic dksA/traR C4-type zinc finger DZR PF12773.7 AII58325.1 - 0.037 14.1 0.5 0.068 13.2 0.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon Peptidase_A8 PF01252.18 AII58326.1 - 4.4e-33 114.5 4.6 5.1e-33 114.3 4.6 1.0 1 0 0 1 1 1 1 Signal peptidase (SPase) II CrgA PF06781.12 AII58326.1 - 0.13 12.3 0.6 0.67 10.1 0.0 2.2 2 0 0 2 2 2 0 Cell division protein CrgA PseudoU_synth_2 PF00849.22 AII58327.1 - 6.8e-35 120.5 0.0 1e-34 119.9 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 AII58327.1 - 1.5e-12 47.0 0.1 4.6e-12 45.5 0.0 1.9 2 0 0 2 2 2 1 S4 domain Ub-Mut7C PF14451.6 AII58327.1 - 0.13 12.1 0.0 0.55 10.1 0.0 2.0 1 0 0 1 1 1 0 Mut7-C ubiquitin HTH_45 PF14947.6 AII58328.1 - 7.6e-24 83.5 0.4 8.8e-24 83.3 0.4 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix DUF4364 PF14277.6 AII58328.1 - 1.6e-05 24.7 0.1 2e-05 24.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) TrmB PF01978.19 AII58328.1 - 0.0099 15.7 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB PEMT PF04191.13 AII58330.1 - 3.8e-06 27.2 4.1 6.9e-06 26.4 4.1 1.4 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.14 AII58330.1 - 0.005 17.2 0.1 0.0094 16.3 0.1 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF202 PF02656.15 AII58330.1 - 7.5 7.1 10.3 3.2 8.2 3.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF202) GH3 PF03321.13 AII58331.1 - 2e-37 129.3 0.0 4.8e-26 91.7 0.0 2.0 2 0 0 2 2 2 2 GH3 auxin-responsive promoter GGDEF PF00990.21 AII58332.1 - 5.8e-43 146.4 0.0 1.1e-42 145.5 0.0 1.5 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain HD PF01966.22 AII58332.1 - 6.9e-25 87.6 0.6 1.7e-24 86.4 0.6 1.7 1 0 0 1 1 1 1 HD domain HD_5 PF13487.6 AII58332.1 - 2.8e-19 69.1 0.0 6.6e-19 67.9 0.0 1.7 1 0 0 1 1 1 1 HD domain HisKA_7TM PF16927.5 AII58332.1 - 1.5e-13 51.3 21.1 1.5e-13 51.3 21.1 2.2 2 0 0 2 2 2 1 N-terminal 7TM region of histidine kinase GAF_2 PF13185.6 AII58332.1 - 1.4e-07 31.9 0.0 2.5e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 AII58332.1 - 3.3e-05 24.2 0.0 6.2e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 GAF domain HDOD PF08668.12 AII58332.1 - 0.00079 19.0 0.1 0.002 17.6 0.0 1.6 2 0 0 2 2 2 1 HDOD domain GAF PF01590.26 AII58332.1 - 0.011 16.4 0.0 0.031 14.9 0.0 1.9 1 0 0 1 1 1 0 GAF domain QRPTase_C PF01729.19 AII58333.1 - 3e-50 170.3 1.0 4.8e-50 169.6 1.0 1.3 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 AII58333.1 - 2.9e-27 94.5 0.1 5.1e-27 93.8 0.1 1.4 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Biotin_lipoyl_2 PF13533.6 AII58333.1 - 0.0052 16.6 0.5 0.013 15.4 0.5 1.7 1 0 0 1 1 1 1 Biotin-lipoyl like Ribul_P_3_epim PF00834.19 AII58333.1 - 0.02 14.3 0.2 0.045 13.1 0.2 1.6 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Glyc_hyd_38C_2 PF18230.1 AII58333.1 - 0.053 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal sub-domain FAD_binding_2 PF00890.24 AII58334.1 - 3.1e-95 319.7 0.4 3.6e-95 319.5 0.4 1.0 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 AII58334.1 - 1.3e-12 47.8 0.0 1.3e-11 44.6 0.0 2.2 1 1 0 1 1 1 1 Fumarate reductase flavoprotein C-term DAO PF01266.24 AII58334.1 - 5.1e-10 39.5 1.6 9.7e-09 35.3 1.6 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 AII58334.1 - 1.5e-08 34.3 1.3 0.0063 15.8 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 AII58334.1 - 0.005 16.2 2.4 0.028 13.8 2.4 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 AII58334.1 - 0.0058 15.4 1.6 0.63 8.7 0.1 2.8 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.22 AII58334.1 - 0.047 12.8 3.0 0.97 8.4 0.1 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 AII58334.1 - 0.21 11.9 1.8 0.57 10.5 1.8 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 AII58334.1 - 0.36 10.0 1.3 11 5.1 0.2 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase YajC PF02699.15 AII58335.1 - 1e-26 92.6 0.5 1.2e-26 92.4 0.5 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Orf78 PF06024.12 AII58335.1 - 0.0062 16.8 0.1 0.0091 16.3 0.1 1.2 1 0 0 1 1 1 1 Orf78 (ac78) DUF4131 PF13567.6 AII58335.1 - 0.037 13.7 0.0 0.037 13.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF4579 PF15158.6 AII58335.1 - 0.071 12.9 0.0 0.082 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4579) Radical_SAM PF04055.21 AII58336.1 - 1e-24 87.8 0.0 2.4e-24 86.6 0.0 1.6 1 1 1 2 2 2 1 Radical SAM superfamily UPF0004 PF00919.20 AII58336.1 - 1.3e-22 79.7 0.0 3e-22 78.5 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 AII58336.1 - 3.1e-05 23.9 0.0 5.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 TRAM domain BTRD1 PF17660.1 AII58336.1 - 0.023 14.5 0.1 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial tandem repeat domain 1 UNC-50 PF05216.13 AII58337.1 - 0.02 14.5 6.6 0.025 14.2 6.6 1.0 1 0 0 1 1 1 0 UNC-50 family MscL PF01741.18 AII58338.1 - 3.5e-41 140.3 0.9 4.2e-41 140.0 0.9 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL UPF0547 PF10571.9 AII58338.1 - 0.00017 21.6 4.6 0.00027 20.9 4.6 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 DZR PF12773.7 AII58338.1 - 0.0015 18.5 1.6 0.002 18.1 1.6 1.2 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 AII58338.1 - 0.0042 16.8 1.9 0.0071 16.0 1.9 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_15 PF17032.5 AII58338.1 - 0.018 15.8 0.1 0.024 15.4 0.1 1.2 1 0 0 1 1 1 0 zinc-ribbon family CopD PF05425.13 AII58338.1 - 0.031 14.6 0.9 0.05 14.0 0.1 1.6 2 0 0 2 2 2 0 Copper resistance protein D zf-ribbon_3 PF13248.6 AII58338.1 - 0.036 13.5 2.2 0.064 12.7 2.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain UPF0239 PF06783.11 AII58338.1 - 0.049 13.8 0.0 0.087 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) Bacteriocin_IIc PF10439.9 AII58338.1 - 0.059 13.5 3.7 0.4 10.8 0.9 2.2 1 1 1 2 2 2 0 Bacteriocin class II with double-glycine leader peptide zf-C3HC4_3 PF13920.6 AII58338.1 - 0.066 13.1 2.9 0.13 12.1 2.8 1.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-CHCC PF10276.9 AII58338.1 - 0.28 11.3 4.4 2.6 8.2 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger domain zf-Di19 PF05605.12 AII58338.1 - 4.3 7.7 7.1 6.8 7.1 0.7 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Fapy_DNA_glyco PF01149.24 AII58339.1 - 3e-31 108.4 0.0 5.9e-31 107.5 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 AII58339.1 - 9.1e-29 99.3 0.0 1.8e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain zf-FPG_IleRS PF06827.14 AII58339.1 - 4.6e-05 23.2 6.9 8.9e-05 22.3 6.9 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS FbpA PF05833.11 AII58339.1 - 0.00041 19.2 0.0 0.00057 18.8 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) A2L_zn_ribbon PF08792.10 AII58339.1 - 0.015 15.0 0.9 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain Zn_ribbon_SprT PF17283.2 AII58339.1 - 0.025 14.5 6.5 0.042 13.8 6.5 1.4 1 0 0 1 1 1 0 SprT-like zinc ribbon domain Auto_anti-p27 PF06677.12 AII58339.1 - 0.045 13.9 4.0 0.077 13.2 4.0 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 AII58339.1 - 0.063 13.3 3.1 0.14 12.2 3.1 1.6 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 AII58339.1 - 0.68 9.7 6.1 2.1 8.2 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 AII58339.1 - 0.89 9.1 8.3 29 4.2 8.3 2.4 1 1 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 AII58339.1 - 1.4 9.1 6.9 0.47 10.6 0.3 2.5 1 1 1 2 2 2 0 Zinc ribbon domain UPF0547 PF10571.9 AII58339.1 - 4.6 7.4 10.2 9.2 6.4 0.9 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 PAP2 PF01569.21 AII58340.1 - 1.2e-17 64.0 6.7 1.2e-17 64.0 6.7 2.4 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 AII58340.1 - 2.9e-07 30.4 1.8 2.9e-07 30.4 1.8 2.3 2 1 1 3 3 3 1 PAP2 superfamily PAP2_C PF14360.6 AII58340.1 - 0.00029 21.3 0.3 0.0009 19.7 0.3 1.8 1 0 0 1 1 1 1 PAP2 superfamily C-terminal HRG PF16954.5 AII58340.1 - 0.077 13.4 0.0 0.077 13.4 0.0 3.4 3 1 1 4 4 4 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene DNA_pol_A PF00476.20 AII58341.1 - 6.9e-154 512.4 0.0 1e-153 511.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A 5_3_exonuc_N PF02739.16 AII58341.1 - 2.8e-48 163.8 0.0 2.6e-47 160.7 0.0 2.1 2 0 0 2 2 2 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 AII58341.1 - 1.1e-32 112.5 0.1 4e-32 110.7 0.0 2.1 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold DNA_pol_A_exo1 PF01612.20 AII58341.1 - 1.3e-09 38.1 0.1 2.1e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 3'-5' exonuclease HHH_5 PF14520.6 AII58341.1 - 0.00071 20.1 0.0 0.0031 18.1 0.0 2.2 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 AII58341.1 - 0.023 14.5 0.2 0.064 13.1 0.2 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_2 PF12826.7 AII58341.1 - 0.055 13.6 0.0 0.31 11.2 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif HTH_AsnC-type PF13404.6 AII58341.1 - 0.091 12.6 0.4 0.94 9.4 0.4 2.6 1 1 0 1 1 1 0 AsnC-type helix-turn-helix domain IMS_HHH PF11798.8 AII58341.1 - 0.15 12.4 0.0 0.51 10.8 0.0 1.9 1 0 0 1 1 1 0 IMS family HHH motif Rhodanese PF00581.20 AII58342.1 - 6.8e-17 61.9 0.0 1.1e-16 61.3 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Synaptobrevin PF00957.21 AII58344.1 - 0.12 12.2 0.3 0.16 11.8 0.3 1.2 1 0 0 1 1 1 0 Synaptobrevin OTCace PF00185.24 AII58345.1 - 5.1e-55 185.8 0.0 7.9e-55 185.2 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 AII58345.1 - 3.6e-48 163.3 0.0 5.3e-48 162.8 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Maf_N PF08383.11 AII58345.1 - 0.2 11.4 0.2 0.78 9.6 0.0 2.0 2 1 0 2 2 2 0 Maf N-terminal region MMR_HSR1 PF01926.23 AII58346.1 - 1e-51 173.8 4.5 2e-25 89.1 0.4 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.6 AII58346.1 - 1.4e-32 111.8 1.1 3e-32 110.8 1.1 1.6 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.18 AII58346.1 - 1.1e-22 80.2 1.2 1.2e-11 44.4 0.1 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B Dynamin_N PF00350.23 AII58346.1 - 7.8e-18 65.1 6.5 0.00023 21.3 0.0 4.2 2 2 2 4 4 4 4 Dynamin family GTP_EFTU PF00009.27 AII58346.1 - 4.7e-17 62.2 7.4 1.9e-05 24.3 0.4 5.2 2 2 1 3 3 3 3 Elongation factor Tu GTP binding domain AIG1 PF04548.16 AII58346.1 - 3.3e-12 46.2 1.7 2.3e-07 30.4 0.1 2.4 2 0 0 2 2 2 2 AIG1 family RsgA_GTPase PF03193.16 AII58346.1 - 3.7e-11 43.2 2.4 0.0048 16.8 0.3 3.9 3 1 0 3 3 3 3 RsgA GTPase Ras PF00071.22 AII58346.1 - 3.1e-09 36.6 0.3 0.00028 20.5 0.0 3.3 2 2 0 2 2 2 2 Ras family Roc PF08477.13 AII58346.1 - 5.5e-09 36.3 1.9 0.0078 16.4 0.1 4.2 2 2 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 AII58346.1 - 4.4e-07 30.5 0.0 0.0099 16.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter TniB PF05621.11 AII58346.1 - 3e-06 26.8 0.0 0.022 14.2 0.0 2.7 2 1 0 2 2 2 2 Bacterial TniB protein cobW PF02492.19 AII58346.1 - 5e-06 26.2 4.5 0.027 14.1 0.2 4.8 3 2 1 5 5 5 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 AII58346.1 - 6.4e-06 26.5 0.0 0.11 12.8 0.0 4.0 4 1 1 5 5 5 2 AAA domain PduV-EutP PF10662.9 AII58346.1 - 6.9e-06 25.9 2.2 2 8.1 0.3 4.1 3 1 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.6 AII58346.1 - 4.4e-05 23.5 0.1 0.039 14.0 0.0 3.3 4 0 0 4 4 3 1 AAA domain Arf PF00025.21 AII58346.1 - 0.00011 21.7 2.5 0.36 10.3 0.5 3.8 3 1 0 3 3 3 1 ADP-ribosylation factor family Septin PF00735.18 AII58346.1 - 0.00028 20.2 0.1 0.51 9.6 0.0 2.2 2 0 0 2 2 2 2 Septin ATPase_2 PF01637.18 AII58346.1 - 0.00037 20.5 1.0 0.17 11.7 0.0 3.2 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea Nuc_deoxyri_tr2 PF15891.5 AII58346.1 - 0.0004 20.7 0.1 0.1 12.9 0.0 2.4 2 0 0 2 2 2 1 Nucleoside 2-deoxyribosyltransferase like AAA_29 PF13555.6 AII58346.1 - 0.00057 19.6 0.0 1.6 8.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain GBP PF02263.19 AII58346.1 - 0.0012 18.2 0.0 1.6 8.0 0.0 2.4 2 0 0 2 2 2 2 Guanylate-binding protein, N-terminal domain AAA_16 PF13191.6 AII58346.1 - 0.0017 18.8 0.0 0.73 10.2 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 AII58346.1 - 0.0021 17.8 0.2 2.1 8.0 0.0 2.6 2 1 0 2 2 2 2 AAA domain SRP54 PF00448.22 AII58346.1 - 0.0025 17.4 2.5 2.2 7.9 0.1 3.5 2 1 1 3 3 3 1 SRP54-type protein, GTPase domain AAA_15 PF13175.6 AII58346.1 - 0.0042 16.8 0.2 0.81 9.3 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 AII58346.1 - 0.0056 17.1 0.0 1.8 9.0 0.0 2.7 3 0 0 3 3 2 1 RNA helicase MMR_HSR1_Xtn PF16897.5 AII58346.1 - 0.0062 16.5 0.0 0.19 11.8 0.0 2.3 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MobB PF03205.14 AII58346.1 - 0.0076 16.2 0.0 1.6 8.7 0.0 2.8 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_21 PF13304.6 AII58346.1 - 0.0082 16.0 0.4 3.8 7.2 0.1 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system NB-ARC PF00931.22 AII58346.1 - 0.0097 15.1 0.0 2.4 7.3 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain SRPRB PF09439.10 AII58346.1 - 0.011 15.2 0.4 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit FtsK_SpoIIIE PF01580.18 AII58346.1 - 0.018 14.4 0.0 2 7.7 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_18 PF13238.6 AII58346.1 - 0.055 14.0 0.1 0.71 10.4 0.0 2.5 3 0 0 3 3 2 0 AAA domain G-alpha PF00503.20 AII58346.1 - 0.075 12.2 0.0 1.3 8.1 0.0 2.7 3 0 0 3 3 3 0 G-protein alpha subunit AAA_23 PF13476.6 AII58346.1 - 0.085 13.4 0.1 3.5 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 AII58346.1 - 0.11 12.7 0.1 1.5 9.0 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 AII58346.1 - 0.33 10.5 1.9 23 4.5 0.0 3.3 2 2 1 3 3 3 0 AAA domain G3P_acyltransf PF02660.15 AII58347.1 - 8.1e-43 146.3 17.9 1e-42 146.0 17.9 1.1 1 0 0 1 1 1 1 Glycerol-3-phosphate acyltransferase NAD_Gly3P_dh_C PF07479.14 AII58348.1 - 6.3e-50 169.1 0.3 1.1e-49 168.4 0.3 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 AII58348.1 - 9.3e-37 126.4 0.0 1.8e-36 125.5 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 AII58348.1 - 3.4e-06 27.6 0.0 1.8e-05 25.3 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 AII58348.1 - 5.5e-06 26.1 0.1 1.2e-05 25.0 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 AII58348.1 - 0.00065 19.9 0.1 0.0019 18.4 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase PDH PF02153.17 AII58348.1 - 0.032 13.3 0.1 0.064 12.2 0.1 1.5 1 0 0 1 1 1 0 Prephenate dehydrogenase DnaJ_C PF01556.18 AII58349.1 - 2.5e-38 131.5 0.1 3.1e-38 131.2 0.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 AII58349.1 - 7.1e-28 96.5 1.6 1.2e-27 95.8 1.6 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 AII58349.1 - 8.3e-14 51.7 16.2 1.4e-13 51.0 16.2 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 AII58349.1 - 0.00014 21.8 15.5 0.0012 18.8 2.1 3.3 1 1 2 3 3 3 3 Tryptophan RNA-binding attenuator protein inhibitory protein HSP70 PF00012.20 AII58350.1 - 5.5e-256 850.5 12.1 6.3e-256 850.3 12.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 AII58350.1 - 3.7e-17 62.1 13.0 1.8e-15 56.6 0.7 3.3 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.16 AII58350.1 - 0.0011 18.8 0.1 0.0033 17.2 0.1 1.9 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 AII58350.1 - 0.11 12.9 6.7 7.8 7.0 0.0 3.7 3 1 0 3 3 3 0 Cell division protein FtsA GrpE PF01025.19 AII58351.1 - 2.2e-39 134.8 0.0 2.6e-39 134.5 0.0 1.0 1 0 0 1 1 1 1 GrpE DUF3391 PF11871.8 AII58351.1 - 0.15 12.6 2.4 0.2 12.2 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) HrcA PF01628.21 AII58352.1 - 1.3e-51 175.6 0.7 1.6e-51 175.3 0.7 1.1 1 0 0 1 1 1 1 HrcA protein C terminal domain HTH_DeoR PF08220.12 AII58352.1 - 0.033 13.9 0.2 0.32 10.8 0.0 2.3 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain Lactamase_B_3 PF13483.6 AII58353.1 - 7.7e-49 165.7 0.0 9.1e-49 165.5 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 AII58353.1 - 6.4e-05 22.6 0.1 0.00026 20.6 0.0 1.8 1 1 0 2 2 2 1 Beta-lactamase superfamily domain FAM104 PF15434.6 AII58353.1 - 0.013 16.1 0.0 0.023 15.3 0.0 1.4 1 0 0 1 1 1 0 Family 104 Peptidase_C14 PF00656.22 AII58354.1 - 5.3e-12 46.2 0.0 7.2e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Peptidase_C13 PF01650.18 AII58354.1 - 1.6e-06 27.8 0.1 2.6e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 Peptidase C13 family CHAT PF12770.7 AII58354.1 - 0.0022 17.5 0.0 0.0036 16.8 0.0 1.3 1 0 0 1 1 1 1 CHAT domain RNase_H_2 PF13482.6 AII58355.1 - 1.5e-39 135.6 0.0 1.7e-39 135.5 0.0 1.0 1 0 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo1 PF03104.19 AII58355.1 - 0.007 15.5 0.0 0.0091 15.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_exo2 PF10108.9 AII58355.1 - 0.044 13.5 0.1 0.57 9.8 0.0 2.1 1 1 1 2 2 2 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Bap31_Bap29_C PF18035.1 AII58356.1 - 0.033 14.2 0.3 0.04 13.9 0.3 1.1 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF4051 PF13260.6 AII58356.1 - 1.4 8.7 5.0 1.4 8.7 4.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4051) Sortilin-Vps10 PF15902.5 AII58357.1 - 4.4e-08 32.4 2.8 0.00038 19.4 0.1 4.4 3 1 1 4 4 4 2 Sortilin, neurotensin receptor 3, BNR PF02012.20 AII58357.1 - 1.6e-07 30.3 16.2 2.3 8.5 0.1 6.6 5 0 0 5 5 5 5 BNR/Asp-box repeat PSII_BNR PF14870.6 AII58357.1 - 0.00012 21.5 8.8 0.54 9.5 0.2 4.3 3 1 2 5 5 5 4 Photosynthesis system II assembly factor YCF48 DUF3827 PF12877.7 AII58357.1 - 1.5 7.1 3.6 2.2 6.6 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) BNR_6 PF15899.5 AII58357.1 - 1.5 9.1 7.2 68 3.9 0.0 4.7 5 0 0 5 5 5 0 BNR-Asp box repeat Rho_RNA_bind PF07497.12 AII58358.1 - 9.3e-31 105.5 0.0 2.1e-30 104.4 0.0 1.6 1 0 0 1 1 1 1 Rho termination factor, RNA-binding domain ATP-synt_ab PF00006.25 AII58358.1 - 7.9e-23 81.2 0.0 3.5e-22 79.1 0.0 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Rho_N PF07498.12 AII58358.1 - 2.6e-10 40.1 0.8 7.6e-10 38.6 0.8 1.9 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain AAA_22 PF13401.6 AII58358.1 - 0.00046 20.5 0.8 0.28 11.4 0.0 2.6 3 0 0 3 3 3 2 AAA domain OB_RNB PF08206.11 AII58358.1 - 0.0033 17.1 0.0 0.0071 16.0 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease B OB domain Mor PF08765.11 AII58358.1 - 0.022 14.8 0.0 0.087 12.8 0.0 2.0 1 0 0 1 1 1 0 Mor transcription activator family AAA PF00004.29 AII58358.1 - 0.023 15.1 0.0 0.072 13.5 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 AII58358.1 - 0.052 13.1 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 AII58358.1 - 0.056 12.9 0.0 0.096 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 AII58358.1 - 0.057 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 AII58358.1 - 0.06 13.6 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AII58358.1 - 0.062 13.9 0.2 0.89 10.1 0.0 2.8 3 0 0 3 3 3 0 AAA domain TAL_FSA PF00923.19 AII58359.1 - 2e-56 191.5 0.1 4.9e-56 190.2 0.1 1.7 1 1 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase CTP_synth_N PF06418.14 AII58360.1 - 5e-126 419.4 0.7 6.3e-126 419.1 0.7 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 AII58360.1 - 1.8e-54 184.4 0.0 3.7e-54 183.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AII58360.1 - 7.2e-07 29.2 0.0 5e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 Peptidase C26 CbiA PF01656.23 AII58360.1 - 0.013 15.5 0.0 0.02 14.9 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PS_pyruv_trans PF04230.13 AII58360.1 - 0.063 13.2 0.0 3.3 7.6 0.0 2.8 3 0 0 3 3 3 0 Polysaccharide pyruvyl transferase DnaJ_C PF01556.18 AII58361.1 - 2.5e-38 131.5 0.0 3.3e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 AII58361.1 - 1.4e-27 95.6 1.7 2.2e-27 94.9 1.7 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 AII58361.1 - 1.6e-05 25.2 1.2 3.1e-05 24.3 1.2 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 AII58361.1 - 0.036 14.0 2.9 0.077 13.0 2.9 1.5 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF1356 PF07092.12 AII58361.1 - 0.083 12.2 0.3 0.12 11.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) MerR_1 PF13411.6 AII58362.1 - 1.5e-18 66.6 0.4 2.3e-18 66.0 0.4 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR_2 PF13591.6 AII58362.1 - 3.1e-09 36.6 0.6 3.8e-09 36.3 0.6 1.2 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 AII58362.1 - 4.6e-09 35.9 1.2 8.2e-09 35.1 1.2 1.3 1 0 0 1 1 1 1 MerR family regulatory protein HTH_17 PF12728.7 AII58362.1 - 0.0015 18.7 0.1 0.0025 18.0 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain TSC22 PF01166.18 AII58362.1 - 0.0044 17.3 0.8 0.0081 16.4 0.8 1.4 1 0 0 1 1 1 1 TSC-22/dip/bun family Cep57_CLD_2 PF14197.6 AII58362.1 - 0.0054 16.8 0.6 0.011 15.8 0.6 1.5 1 0 0 1 1 1 1 Centrosome localisation domain of PPC89 ZapB PF06005.12 AII58362.1 - 0.026 14.9 3.3 0.033 14.6 2.9 1.4 1 1 0 1 1 1 0 Cell division protein ZapB LcrG PF07216.12 AII58362.1 - 0.029 14.3 2.2 0.039 13.9 2.2 1.2 1 0 0 1 1 1 0 LcrG protein Shugoshin_N PF07558.11 AII58362.1 - 0.03 14.2 3.4 0.03 14.2 3.4 1.8 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region bZIP_2 PF07716.15 AII58362.1 - 0.038 14.1 3.1 0.038 14.1 3.1 1.6 2 0 0 2 2 2 0 Basic region leucine zipper Mto2_bdg PF12808.7 AII58362.1 - 0.051 13.9 3.0 0.1 12.9 3.0 1.5 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region HALZ PF02183.18 AII58362.1 - 0.1 12.9 0.5 0.1 12.9 0.5 1.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 AII58362.1 - 0.1 12.7 0.8 0.1 12.7 0.8 1.6 2 0 0 2 2 2 0 bZIP transcription factor AAA_2 PF07724.14 AII58363.1 - 3.1e-60 203.2 0.1 2.9e-56 190.2 0.0 3.2 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 AII58363.1 - 3.1e-36 123.4 5.6 1.4e-35 121.4 5.6 2.2 1 0 0 1 1 1 1 AAA lid domain ClpB_D2-small PF10431.9 AII58363.1 - 1e-27 96.0 0.1 5.7e-27 93.6 0.1 2.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 AII58363.1 - 1.2e-24 87.3 0.0 1.9e-13 51.0 0.1 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Clp_N PF02861.20 AII58363.1 - 1.2e-23 82.9 4.6 4.2e-12 46.0 0.2 3.0 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_5 PF07728.14 AII58363.1 - 1.2e-16 61.0 0.1 2.1e-12 47.2 0.0 3.2 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 AII58363.1 - 1.6e-11 44.2 0.0 1.3e-06 28.2 0.0 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.6 AII58363.1 - 8.5e-11 42.5 10.4 2.9e-06 27.7 0.1 4.9 4 2 0 5 5 4 2 AAA ATPase domain AAA_22 PF13401.6 AII58363.1 - 3.1e-08 34.0 7.5 0.0022 18.3 0.1 5.7 4 2 1 5 5 5 2 AAA domain TniB PF05621.11 AII58363.1 - 7.4e-07 28.8 0.0 0.0029 17.0 0.0 4.3 3 1 0 3 3 3 1 Bacterial TniB protein NACHT PF05729.12 AII58363.1 - 3.9e-06 26.9 0.0 0.0075 16.2 0.0 3.4 3 0 0 3 3 3 1 NACHT domain AAA_14 PF13173.6 AII58363.1 - 5e-06 26.6 0.0 0.15 12.1 0.0 3.2 2 1 1 3 3 3 2 AAA domain IstB_IS21 PF01695.17 AII58363.1 - 5.3e-06 26.3 0.1 0.094 12.4 0.0 3.1 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 AII58363.1 - 2.2e-05 24.0 0.0 0.23 11.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region ResIII PF04851.15 AII58363.1 - 4.3e-05 23.6 0.0 0.12 12.4 0.0 3.8 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 AII58363.1 - 8.9e-05 22.5 11.2 0.011 15.7 0.0 5.2 3 2 2 6 6 6 1 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 AII58363.1 - 0.00033 20.1 0.0 2 7.7 0.0 3.2 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI TsaE PF02367.17 AII58363.1 - 0.00061 19.8 0.0 2.5 8.1 0.0 3.1 3 0 0 3 3 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 AII58363.1 - 0.00071 19.7 0.1 1.5 9.0 0.0 3.7 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 AII58363.1 - 0.0011 18.9 0.0 2 8.3 0.0 2.9 3 0 0 3 3 2 2 RsgA GTPase RuvB_N PF05496.12 AII58363.1 - 0.0011 18.8 1.1 7.7 6.2 0.0 4.4 3 1 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 AII58363.1 - 0.0011 19.5 0.1 2.8 8.5 0.0 3.5 4 0 0 4 4 2 1 AAA domain DNA_pol3_delta2 PF13177.6 AII58363.1 - 0.0015 18.3 0.0 0.31 10.8 0.0 3.6 2 1 0 2 2 2 1 DNA polymerase III, delta subunit RNA_helicase PF00910.22 AII58363.1 - 0.002 18.5 0.0 4.4 7.7 0.0 3.0 3 0 0 3 3 2 1 RNA helicase Roc PF08477.13 AII58363.1 - 0.0025 18.0 0.0 4.4 7.6 0.0 3.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 AII58363.1 - 0.0044 16.8 0.1 3.9 7.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 AII58363.1 - 0.0066 15.5 0.0 0.11 11.5 0.0 2.7 2 2 0 2 2 2 1 Type II/IV secretion system protein NB-ARC PF00931.22 AII58363.1 - 0.0067 15.6 0.4 0.12 11.5 0.0 2.9 3 0 0 3 3 2 1 NB-ARC domain AAA_3 PF07726.11 AII58363.1 - 0.008 16.0 0.0 0.29 11.0 0.0 3.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 AII58363.1 - 0.01 15.6 2.2 1 9.1 0.0 3.8 3 1 1 4 4 3 0 AAA domain Zeta_toxin PF06414.12 AII58363.1 - 0.011 15.0 0.0 3.6 6.8 0.0 2.9 2 0 0 2 2 2 0 Zeta toxin PhoH PF02562.16 AII58363.1 - 0.014 14.8 0.0 1.7 8.0 0.0 2.7 2 0 0 2 2 2 0 PhoH-like protein AAA_23 PF13476.6 AII58363.1 - 0.015 15.8 0.0 0.015 15.8 0.0 4.5 3 2 0 3 3 2 0 AAA domain ABC_tran PF00005.27 AII58363.1 - 0.025 15.1 0.0 13 6.4 0.0 3.6 3 0 0 3 3 3 0 ABC transporter TIP49 PF06068.13 AII58363.1 - 0.06 12.5 3.6 0.65 9.1 0.1 3.4 3 1 1 4 4 4 0 TIP49 P-loop domain NTPase_1 PF03266.15 AII58363.1 - 0.093 12.6 1.6 3.5 7.5 0.0 3.8 4 0 0 4 4 3 0 NTPase DUF87 PF01935.17 AII58363.1 - 0.14 12.2 3.6 2.1 8.4 0.0 3.6 3 1 0 3 3 3 0 Helicase HerA, central domain SNARE_assoc PF09335.11 AII58364.1 - 1.1e-10 42.1 7.0 1.1e-10 42.1 7.0 2.5 1 1 1 2 2 2 1 SNARE associated Golgi protein GATase_7 PF13537.6 AII58365.1 - 6.1e-24 84.3 0.0 3.8e-23 81.7 0.0 2.0 1 1 1 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.6 AII58365.1 - 2.1e-21 76.5 0.0 3.4e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 AII58365.1 - 4.4e-07 29.6 0.1 8.8e-07 28.6 0.1 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 AII58365.1 - 0.00015 20.8 0.0 0.0003 19.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II PRTase_2 PF15609.6 AII58365.1 - 0.019 14.4 0.0 0.1 12.1 0.0 1.9 2 0 0 2 2 2 0 Phosphoribosyl transferase AIRS_C PF02769.22 AII58366.1 - 1.8e-26 93.1 0.0 3e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 AII58366.1 - 3e-15 56.7 0.1 5.1e-15 55.9 0.1 1.4 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Methyltransf_11 PF08241.12 AII58367.1 - 1.3e-23 83.5 0.0 2e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AII58367.1 - 5.3e-19 68.7 0.0 1e-18 67.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AII58367.1 - 1.6e-16 60.5 0.0 2.2e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AII58367.1 - 2.5e-16 60.0 0.0 3.1e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AII58367.1 - 1.1e-14 55.0 0.0 1.7e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AII58367.1 - 5e-14 52.2 0.0 2.3e-13 50.0 0.0 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 AII58367.1 - 0.00027 20.7 0.0 0.00058 19.7 0.0 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.15 AII58367.1 - 0.0023 17.8 0.0 0.0033 17.3 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 AII58367.1 - 0.0031 17.1 0.0 0.0045 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 AII58367.1 - 0.0032 17.4 0.0 0.0049 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 AII58367.1 - 0.0062 16.5 0.0 0.0089 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 AII58367.1 - 0.008 15.3 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MetW PF07021.12 AII58367.1 - 0.016 14.8 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_PK PF05891.12 AII58367.1 - 0.022 14.2 0.0 0.077 12.5 0.0 1.9 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_4 PF02390.17 AII58367.1 - 0.045 13.2 0.0 0.91 9.0 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase DREV PF05219.12 AII58367.1 - 0.1 11.7 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Pterin_bind PF00809.22 AII58367.1 - 0.15 11.7 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Pterin binding enzyme AICARFT_IMPCHas PF01808.18 AII58368.1 - 4e-113 377.8 0.3 5e-113 377.5 0.3 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 AII58368.1 - 1.9e-27 95.2 0.0 5.3e-27 93.9 0.0 1.8 2 0 0 2 2 2 1 MGS-like domain QRPTase_C PF01729.19 AII58369.1 - 2.1e-18 66.7 0.0 2.8e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 AII58369.1 - 1.7e-08 34.4 0.0 3.3e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain MazE_antitoxin PF04014.18 AII58370.1 - 1.7e-05 24.6 0.0 2.3e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin PmrD PF11183.8 AII58370.1 - 0.092 12.9 0.0 0.17 12.0 0.0 1.4 1 1 0 1 1 1 0 Polymyxin resistance protein PmrD AbrB-like PF14250.6 AII58370.1 - 0.14 12.2 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 AbrB-like transcriptional regulator Thump_like PF18096.1 AII58370.1 - 0.17 11.9 0.0 0.21 11.6 0.0 1.1 1 0 0 1 1 1 0 THUMP domain-like Methyltransf_31 PF13847.6 AII58371.1 - 3.5e-37 127.5 0.0 6.7e-37 126.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 AII58371.1 - 7e-23 81.2 0.4 1.5e-22 80.1 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 AII58371.1 - 7.4e-22 77.8 0.0 1.8e-21 76.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AII58371.1 - 6.3e-21 74.8 0.0 1.1e-20 74.0 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 AII58371.1 - 1.3e-11 44.6 0.0 1.8e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AII58371.1 - 4.6e-11 43.3 0.0 1.1e-10 42.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 AII58371.1 - 1.7e-09 37.7 0.0 4.1e-09 36.5 0.0 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 AII58371.1 - 9.1e-08 31.8 0.0 1.3e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 AII58371.1 - 0.00011 21.9 0.0 0.00023 20.9 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_8 PF05148.15 AII58371.1 - 0.00015 21.7 0.1 0.00031 20.7 0.1 1.6 1 1 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 AII58371.1 - 0.00016 21.2 0.0 0.00016 21.2 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase small domain ADH_zinc_N PF00107.26 AII58371.1 - 0.0005 20.1 0.0 0.00097 19.1 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase FtsJ PF01728.19 AII58371.1 - 0.0024 18.0 0.0 0.0063 16.6 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase GidB PF02527.15 AII58371.1 - 0.011 15.1 0.1 0.076 12.3 0.1 2.0 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_3 PF01596.17 AII58371.1 - 0.034 13.3 0.0 0.063 12.4 0.0 1.3 1 1 0 1 1 1 0 O-methyltransferase Methyltransf_24 PF13578.6 AII58371.1 - 0.037 15.0 0.0 0.066 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 AII58371.1 - 0.068 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_29 PF03141.16 AII58371.1 - 0.17 10.4 0.0 0.24 9.9 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase ATP_bind_3 PF01171.20 AII58372.1 - 5.1e-47 160.0 0.0 8e-47 159.3 0.0 1.3 1 0 0 1 1 1 1 PP-loop family TilS_C PF11734.8 AII58372.1 - 3.8e-15 55.1 0.2 7.6e-15 54.1 0.2 1.5 1 0 0 1 1 1 1 TilS substrate C-terminal domain B3_4 PF03483.17 AII58372.1 - 0.0012 18.6 0.0 0.0044 16.7 0.0 1.9 2 0 0 2 2 2 1 B3/4 domain TilS PF09179.11 AII58372.1 - 0.002 18.6 0.1 0.0055 17.2 0.1 1.7 1 0 0 1 1 1 1 TilS substrate binding domain tRNA_Me_trans PF03054.16 AII58372.1 - 0.023 13.5 0.0 0.065 12.0 0.0 1.6 2 0 0 2 2 2 0 tRNA methyl transferase PAPS_reduct PF01507.19 AII58372.1 - 0.17 11.9 0.0 0.48 10.4 0.0 1.8 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family His_Phos_1 PF00300.22 AII58373.1 - 8.8e-56 188.7 0.0 9.8e-56 188.5 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Peptidase_M48_N PF16491.5 AII58374.1 - 2.2e-28 99.4 3.8 2.2e-28 99.4 3.8 2.0 2 1 0 3 3 3 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 AII58374.1 - 9.7e-22 77.7 0.1 2e-21 76.7 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M48 Peptidase_M56 PF05569.11 AII58374.1 - 2.4e-07 30.2 0.1 7.8e-07 28.6 0.0 1.9 2 1 0 2 2 2 1 BlaR1 peptidase M56 MFS_1 PF07690.16 AII58374.1 - 0.00014 20.9 16.7 0.0043 16.0 12.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily SprT-like PF10263.9 AII58374.1 - 0.088 12.7 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 SprT-like family PspB PF06667.12 AII58374.1 - 0.1 12.6 0.5 0.57 10.3 0.1 2.5 2 0 0 2 2 2 0 Phage shock protein B Spore_III_AF PF09581.10 AII58374.1 - 0.16 12.0 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) DUF2721 PF11026.8 AII58374.1 - 0.89 9.5 14.0 0.87 9.5 0.1 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2721) Peptidase_U4 PF03419.13 AII58374.1 - 1.3 8.2 13.0 11 5.2 0.0 2.5 2 1 0 2 2 2 0 Sporulation factor SpoIIGA DUF2344 PF10105.9 AII58375.1 - 1e-50 172.0 0.0 1.2e-50 171.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2344) DUF21 PF01595.20 AII58376.1 - 4.1e-54 182.9 4.2 5.5e-54 182.5 4.2 1.1 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 AII58376.1 - 9.5e-23 80.0 0.3 1.8e-22 79.1 0.3 1.5 1 0 0 1 1 1 1 Transporter associated domain CBS PF00571.28 AII58376.1 - 2e-16 60.2 0.2 1.5e-07 31.7 0.0 2.6 2 0 0 2 2 2 2 CBS domain HGTP_anticodon PF03129.20 AII58376.1 - 0.11 12.7 0.0 0.4 10.9 0.0 1.9 2 0 0 2 2 2 0 Anticodon binding domain Peptidase_M22 PF00814.25 AII58377.1 - 2.8e-95 319.1 0.0 3.2e-95 318.9 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 AII58377.1 - 3.5e-05 23.6 0.5 0.00033 20.4 0.0 2.4 2 1 1 3 3 3 1 Carbamoyltransferase N-terminus GATase PF00117.28 AII58377.1 - 0.18 11.5 0.1 10 5.9 0.0 2.2 2 0 0 2 2 2 0 Glutamine amidotransferase class-I Cpn10 PF00166.21 AII58378.1 - 1.3e-29 102.1 0.2 1.4e-29 102.0 0.2 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cpn60_TCP1 PF00118.24 AII58379.1 - 7.1e-91 305.3 14.0 1.1e-90 304.6 14.0 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF4661 PF15576.6 AII58379.1 - 0.15 12.0 0.1 0.41 10.5 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4661) KfrA_N PF11740.8 AII58379.1 - 3.7 8.3 9.8 6.5 7.5 4.2 2.8 2 1 0 2 2 2 0 Plasmid replication region DNA-binding N-term Peptidase_M16_C PF05193.21 AII58380.1 - 1.4e-40 139.2 0.0 1e-38 133.2 0.0 2.4 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 AII58380.1 - 6.1e-40 136.6 0.0 1.1e-39 135.9 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M55 PF04951.13 AII58380.1 - 0.072 12.5 0.0 0.31 10.4 0.0 1.9 2 0 0 2 2 2 0 D-aminopeptidase HypA PF01155.19 AII58381.1 - 3.3e-32 110.8 0.4 3.7e-32 110.7 0.4 1.0 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 AII58381.1 - 0.00029 20.9 0.7 0.00059 19.9 0.7 1.5 1 0 0 1 1 1 1 Zinc ribbon domain Prok-RING_1 PF14446.6 AII58381.1 - 0.011 15.7 0.1 0.019 14.9 0.1 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 TackOD1 PF18551.1 AII58381.1 - 0.018 14.7 0.1 0.025 14.3 0.1 1.2 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 Trm112p PF03966.16 AII58381.1 - 0.036 14.6 0.1 1.4 9.6 0.0 2.3 2 1 0 2 2 2 0 Trm112p-like protein Rubredoxin_2 PF18073.1 AII58381.1 - 0.036 13.8 6.6 0.24 11.1 6.6 2.0 1 1 0 1 1 1 0 Rubredoxin metal binding domain Rubredoxin PF00301.20 AII58381.1 - 0.066 13.3 0.5 1.5 8.9 0.0 2.2 2 0 0 2 2 2 0 Rubredoxin zinc_ribbon_4 PF13717.6 AII58381.1 - 0.069 13.1 3.0 0.89 9.5 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_10 PF10058.9 AII58381.1 - 0.089 12.5 0.3 12 5.7 0.1 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Zn_Tnp_IS1595 PF12760.7 AII58381.1 - 0.32 11.0 4.0 7.7 6.6 0.5 2.4 1 1 1 2 2 2 0 Transposase zinc-ribbon domain UPF0547 PF10571.9 AII58381.1 - 0.86 9.8 5.0 1.6 8.9 0.4 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 cobW PF02492.19 AII58382.1 - 3.5e-25 88.6 0.0 4.5e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain DUF3237 PF11578.8 AII58382.1 - 0.022 14.6 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3237) RsgA_GTPase PF03193.16 AII58382.1 - 0.14 12.1 0.1 1.8 8.5 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Sua5_yciO_yrdC PF01300.18 AII58383.1 - 6.8e-51 172.3 0.0 1.1e-50 171.6 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination HypF_C PF17788.1 AII58383.1 - 1.1e-35 122.4 0.1 1.9e-35 121.6 0.1 1.4 1 0 0 1 1 1 1 HypF Kae1-like domain zf-HYPF PF07503.12 AII58383.1 - 5e-34 115.8 17.1 2.3e-18 65.7 2.8 2.7 2 0 0 2 2 2 2 HypF finger Acylphosphatase PF00708.18 AII58383.1 - 2.4e-21 75.9 0.0 4.6e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 Acylphosphatase Peptidase_M22 PF00814.25 AII58383.1 - 1.4e-05 24.9 0.4 0.18 11.4 0.0 2.4 2 0 0 2 2 2 2 Glycoprotease family BcrAD_BadFG PF01869.20 AII58383.1 - 0.065 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family DZR PF12773.7 AII58383.1 - 0.12 12.4 10.0 4.7 7.3 10.0 2.8 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 AII58383.1 - 0.14 12.3 12.3 0.11 12.7 1.0 3.6 3 1 1 4 4 4 0 Zinc ribbon domain HupF_HypC PF01455.18 AII58384.1 - 1.3e-24 86.1 0.1 1.4e-24 86.0 0.1 1.0 1 0 0 1 1 1 1 HupF/HypC family HypD PF01924.16 AII58385.1 - 8.1e-147 488.9 0.0 9.3e-147 488.7 0.0 1.0 1 0 0 1 1 1 1 Hydrogenase formation hypA family AIRS_C PF02769.22 AII58386.1 - 1.9e-27 96.3 0.1 2.7e-27 95.8 0.1 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 AII58386.1 - 3.5e-19 69.2 2.5 3.7e-19 69.2 0.9 1.8 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain TetR_N PF00440.23 AII58387.1 - 8.2e-18 63.9 0.1 2.1e-17 62.6 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_23 PF13384.6 AII58387.1 - 0.055 13.3 0.0 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 Homeodomain-like domain DUF2976 PF11190.8 AII58388.1 - 0.12 12.2 0.8 1.2 8.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) GAD-like PF08887.11 AII58388.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 GAD-like domain TMEM238 PF15125.6 AII58388.1 - 4 7.7 7.1 2.6 8.3 0.5 2.4 2 1 0 2 2 2 0 TMEM238 protein family DUF2613 PF11021.8 AII58389.1 - 2.8 8.1 9.2 0.81 9.8 2.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2613) G3P_acyltransf PF02660.15 AII58390.1 - 4.1e-35 121.3 14.3 4.7e-35 121.1 14.3 1.0 1 0 0 1 1 1 1 Glycerol-3-phosphate acyltransferase HTH_17 PF12728.7 AII58391.1 - 5.3e-09 36.1 0.0 8.5e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain MerR PF00376.23 AII58391.1 - 1.1e-07 31.5 0.1 3.5e-07 29.9 0.1 1.8 2 0 0 2 2 2 1 MerR family regulatory protein HTH_23 PF13384.6 AII58391.1 - 1.5e-06 27.8 0.0 3.4e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 AII58391.1 - 3e-06 27.1 0.1 5.9e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn helix MerR_1 PF13411.6 AII58391.1 - 3.5e-06 27.0 0.1 3.5e-05 23.8 0.0 2.4 2 1 2 4 4 3 1 MerR HTH family regulatory protein HTH_11 PF08279.12 AII58391.1 - 0.00012 21.9 0.1 0.00047 20.0 0.0 2.0 2 0 0 2 2 2 1 HTH domain HTH_3 PF01381.22 AII58391.1 - 0.00016 21.6 0.1 0.0004 20.4 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix HTH_Tnp_ISL3 PF13542.6 AII58391.1 - 0.00019 20.8 0.0 0.00034 20.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_psq PF05225.16 AII58391.1 - 0.00026 20.6 0.4 0.00058 19.5 0.0 1.7 2 0 0 2 2 2 1 helix-turn-helix, Psq domain Sigma70_r4_2 PF08281.12 AII58391.1 - 0.0008 19.0 0.1 0.0017 18.0 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 AII58391.1 - 0.00089 18.7 0.2 0.022 14.3 0.1 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 AbiEi_4 PF13338.6 AII58391.1 - 0.00099 19.2 0.3 0.0042 17.2 0.0 2.0 2 0 0 2 2 2 1 Transcriptional regulator, AbiEi antitoxin HTH_38 PF13936.6 AII58391.1 - 0.001 18.8 0.1 0.0024 17.6 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 AII58391.1 - 0.0023 18.0 0.0 0.0045 17.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_DeoR PF08220.12 AII58391.1 - 0.0028 17.4 0.0 0.0065 16.2 0.0 1.6 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_8 PF02954.19 AII58391.1 - 0.0029 17.4 0.1 0.0084 15.9 0.1 1.8 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family HTH_31 PF13560.6 AII58391.1 - 0.004 17.5 0.1 0.013 15.8 0.0 1.9 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.15 AII58391.1 - 0.0053 16.8 0.4 0.031 14.3 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase DUF1323 PF07037.11 AII58391.1 - 0.02 15.3 0.0 0.031 14.6 0.0 1.4 1 1 0 1 1 1 0 Putative transcription regulator (DUF1323) NUMOD1 PF07453.13 AII58391.1 - 0.023 14.9 0.0 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 NUMOD1 domain DUF3584 PF12128.8 AII58391.1 - 0.027 12.0 0.5 0.034 11.7 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HTH_24 PF13412.6 AII58391.1 - 0.032 13.8 0.1 0.13 11.8 0.0 2.0 3 0 0 3 3 2 0 Winged helix-turn-helix DNA-binding DHR10 PF18595.1 AII58391.1 - 0.04 14.0 0.6 0.059 13.4 0.6 1.2 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain HTH_1 PF00126.27 AII58391.1 - 0.047 13.7 0.4 0.85 9.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_40 PF14493.6 AII58391.1 - 0.055 13.9 0.4 0.18 12.3 0.4 1.9 1 1 0 1 1 1 0 Helix-turn-helix domain YdaS_antitoxin PF15943.5 AII58391.1 - 0.056 13.3 0.1 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DUF746 PF05344.11 AII58391.1 - 0.057 13.3 0.0 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) RWP-RK PF02042.15 AII58391.1 - 0.06 13.3 0.1 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 RWP-RK domain GerE PF00196.19 AII58391.1 - 0.1 12.2 0.0 0.26 10.9 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family zinc_ribbon_2 PF13240.6 AII58392.1 - 0.011 15.5 2.5 0.72 9.6 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain GFA PF04828.14 AII58392.1 - 0.011 16.0 1.0 0.011 16.0 1.0 1.8 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-UBR PF02207.20 AII58392.1 - 0.018 15.2 0.7 0.02 15.0 0.7 1.1 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) HypA PF01155.19 AII58392.1 - 0.021 14.9 1.0 0.021 14.8 1.0 1.0 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_15 PF17032.5 AII58392.1 - 0.032 15.0 1.8 0.038 14.7 1.8 1.1 1 0 0 1 1 1 0 zinc-ribbon family DZR PF12773.7 AII58392.1 - 0.061 13.4 3.3 0.12 12.4 3.3 1.5 1 1 0 1 1 1 0 Double zinc ribbon zf-IS66 PF13005.7 AII58392.1 - 0.083 13.3 1.3 0.2 12.1 0.2 1.9 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 Rubredoxin_2 PF18073.1 AII58392.1 - 0.11 12.2 3.1 0.49 10.2 0.2 2.1 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-A20 PF01754.16 AII58392.1 - 0.36 10.8 6.5 3.2 7.8 2.2 2.4 2 0 0 2 2 2 0 A20-like zinc finger MarC PF01914.17 AII58393.1 - 5e-41 140.3 17.6 7.1e-41 139.8 17.6 1.1 1 0 0 1 1 1 1 MarC family integral membrane protein TerC PF03741.16 AII58393.1 - 0.0015 18.3 4.3 0.0015 18.3 4.3 2.4 1 1 1 2 2 2 1 Integral membrane protein TerC family Polyketide_cyc2 PF10604.9 AII58394.1 - 5.6e-10 39.6 0.1 1.4e-09 38.3 0.1 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 AII58394.1 - 3.4e-08 33.8 0.0 4e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 AII58394.1 - 3.8e-05 23.9 0.0 4.8e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein COXG PF06240.13 AII58394.1 - 0.0039 16.9 0.0 0.0051 16.6 0.0 1.2 1 0 0 1 1 1 1 Carbon monoxide dehydrogenase subunit G (CoxG) GGACT PF06094.12 AII58396.1 - 4.6e-10 40.2 0.0 5.4e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 AII58396.1 - 7e-08 32.8 0.0 9.7e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family Ribosomal_TL5_C PF14693.6 AII58397.1 - 3.2e-19 69.1 0.1 5.9e-19 68.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein TL5, C-terminal domain Ribosomal_L25p PF01386.19 AII58397.1 - 1.1e-15 57.8 0.0 2.1e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L25p family Nanovirus_C8 PF05629.11 AII58397.1 - 0.19 11.8 0.0 0.26 11.4 0.0 1.2 1 0 0 1 1 1 0 Nanovirus component 8 (C8) protein Amidohydro_2 PF04909.14 AII58398.1 - 3.5e-35 122.2 0.0 4.2e-35 121.9 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase LigT_PEase PF02834.16 AII58399.1 - 7.8e-29 99.7 0.0 4.6e-14 52.4 0.0 2.1 2 0 0 2 2 2 2 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.6 AII58399.1 - 1.1e-11 44.9 0.0 1.3e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Gag_spuma PF03276.14 AII58399.1 - 0.064 11.7 0.0 0.082 11.3 0.0 1.1 1 0 0 1 1 1 0 Spumavirus gag protein DUF1936 PF09151.10 AII58400.1 - 0.065 13.1 4.2 0.067 13.1 0.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1936) Pribosyltran PF00156.27 AII58401.1 - 3e-05 23.6 0.0 4.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain AAA_16 PF13191.6 AII58401.1 - 0.018 15.4 0.0 0.025 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain DZR PF12773.7 AII58401.1 - 4.3 7.5 12.3 2 8.5 9.8 1.8 2 0 0 2 2 2 0 Double zinc ribbon Ribosomal_S30AE PF02482.19 AII58402.1 - 1.1e-13 51.8 0.7 1.7e-13 51.1 0.7 1.3 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein Ribosom_S30AE_C PF16321.5 AII58402.1 - 1.9e-11 43.5 0.0 3.9e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Sigma 54 modulation/S30EA ribosomal protein C terminus DNA_binding_1 PF01035.20 AII58403.1 - 2.8e-31 107.5 0.0 3.8e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Inhibitor_I42 PF09394.10 AII58404.1 - 5.9e-20 71.5 0.0 6.9e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Chagasin family peptidase inhibitor I42 RadC PF04002.15 AII58405.1 - 8.8e-40 135.5 0.1 1.7e-39 134.6 0.1 1.4 1 0 0 1 1 1 1 RadC-like JAB domain HHH_2 PF12826.7 AII58405.1 - 2.7e-05 24.2 0.0 6.3e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 AII58405.1 - 0.0054 17.3 0.1 0.011 16.3 0.1 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 AII58405.1 - 0.0056 16.5 0.1 0.014 15.2 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif Prok-JAB PF14464.6 AII58405.1 - 0.026 14.3 0.0 0.04 13.7 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain DUF2007 PF09413.10 AII58406.1 - 4.5e-07 29.9 0.0 6e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Putative prokaryotic signal transducing protein DNA_pol3_alpha PF07733.12 AII58407.1 - 3.6e-98 328.3 0.1 6e-98 327.6 0.1 1.4 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha NTPase domain DNA_pol3_finger PF17657.1 AII58407.1 - 2.2e-59 199.5 0.0 3.7e-59 198.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha subunit finger domain PHP PF02811.19 AII58407.1 - 2.6e-59 200.3 0.3 7.6e-59 198.8 0.3 1.9 1 0 0 1 1 1 1 PHP domain HHH_6 PF14579.6 AII58407.1 - 8.7e-30 102.8 0.1 4.8e-29 100.5 0.1 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif tRNA_anti-codon PF01336.25 AII58407.1 - 2.5e-10 40.2 0.2 5.2e-10 39.2 0.2 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF1461 PF07314.11 AII58408.1 - 3.6e-41 141.1 0.1 4.3e-41 140.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1461) DctQ PF04290.12 AII58408.1 - 0.065 13.2 0.8 0.25 11.3 0.0 2.0 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component PhaG_MnhG_YufB PF03334.14 AII58408.1 - 0.069 13.4 0.2 0.069 13.4 0.2 2.7 3 0 0 3 3 3 0 Na+/H+ antiporter subunit LMBR1 PF04791.16 AII58408.1 - 0.099 11.5 1.3 0.17 10.7 1.3 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein LRR19-TM PF15176.6 AII58408.1 - 0.18 11.8 0.1 0.3 11.1 0.1 1.3 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain CBM_19 PF03427.13 AII58409.1 - 0.1 12.6 0.3 0.2 11.7 0.3 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) Zn-ribbon_8 PF09723.10 AII58410.1 - 9.1e-14 51.3 1.9 9.1e-14 51.3 1.9 2.1 3 0 0 3 3 3 1 Zinc ribbon domain Prok-RING_1 PF14446.6 AII58410.1 - 0.0026 17.6 2.6 0.0026 17.6 2.6 2.3 2 1 0 2 2 2 1 Prokaryotic RING finger family 1 HypA PF01155.19 AII58410.1 - 0.03 14.3 2.5 0.03 14.3 2.5 1.6 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_ribbon_SprT PF17283.2 AII58410.1 - 0.039 13.9 2.0 0.039 13.9 2.0 3.0 2 1 1 3 3 3 0 SprT-like zinc ribbon domain zf-HIT PF04438.16 AII58410.1 - 0.088 12.7 0.9 0.088 12.7 0.9 3.4 2 1 1 3 3 3 0 HIT zinc finger zf_C2H2_10 PF18414.1 AII58410.1 - 0.14 11.8 0.1 0.14 11.8 0.1 2.7 3 0 0 3 3 3 0 C2H2 type zinc-finger zf-UDP PF14569.6 AII58410.1 - 0.22 11.7 0.2 0.22 11.7 0.2 2.5 2 1 1 3 3 3 0 Zinc-binding RING-finger zf_UBZ PF18439.1 AII58410.1 - 0.24 11.0 0.2 0.24 11.0 0.2 2.9 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_9 PF14369.6 AII58410.1 - 0.43 10.9 0.3 0.43 10.9 0.3 3.4 4 0 0 4 4 4 0 zinc-ribbon zf-TFIIB PF13453.6 AII58410.1 - 0.43 10.0 0.1 0.43 10.0 0.1 3.7 3 1 0 3 3 3 0 Transcription factor zinc-finger Acetyltransf_3 PF13302.7 AII58411.1 - 2.9e-26 92.8 0.0 3.4e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 AII58411.1 - 6.7e-08 32.8 0.0 7.8e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AII58411.1 - 1.7e-07 31.5 0.0 2.2e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 AII58411.1 - 0.0083 15.8 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GATase PF00117.28 AII58412.1 - 3.2e-51 173.8 0.0 3.8e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 AII58412.1 - 1.7e-10 41.0 0.2 4.5e-10 39.7 0.2 1.6 1 1 0 1 1 1 1 Peptidase C26 Glycos_transf_3 PF00591.21 AII58413.1 - 8.7e-94 313.8 1.7 9e-94 313.8 0.7 1.4 2 0 0 2 2 2 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 AII58413.1 - 4e-21 74.6 2.2 5.8e-21 74.1 1.1 1.9 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain IGPS PF00218.21 AII58414.1 - 3e-87 292.0 0.0 3.3e-87 291.8 0.0 1.0 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase His_biosynth PF00977.21 AII58414.1 - 1.8e-05 24.4 0.0 0.18 11.2 0.0 2.1 2 0 0 2 2 2 2 Histidine biosynthesis protein NanE PF04131.14 AII58414.1 - 0.00018 20.8 0.1 0.0059 15.8 0.1 2.7 3 1 0 3 3 3 1 Putative N-acetylmannosamine-6-phosphate epimerase ThiG PF05690.14 AII58414.1 - 0.0002 20.7 0.0 0.018 14.4 0.1 2.1 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG QRPTase_C PF01729.19 AII58414.1 - 0.00078 19.3 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain PRAI PF00697.22 AII58415.1 - 8.4e-47 159.5 0.0 9.9e-47 159.2 0.0 1.0 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase TMP-TENI PF02581.17 AII58415.1 - 0.029 13.7 0.1 0.068 12.5 0.1 1.9 1 1 0 1 1 1 0 Thiamine monophosphate synthase DAHP_synth_1 PF00793.20 AII58416.1 - 6.8e-75 251.5 0.0 9.6e-75 251.0 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family DAHP_snth_FXD PF18152.1 AII58416.1 - 1.2e-14 53.9 0.2 2.9e-14 52.6 0.2 1.7 1 0 0 1 1 1 1 DAHP synthase ferredoxin-like domain NeuB PF03102.14 AII58416.1 - 1.7e-09 37.5 0.2 7.2e-09 35.4 0.2 1.8 1 1 0 1 1 1 1 NeuB family PALP PF00291.25 AII58417.1 - 6.4e-52 176.8 0.6 8e-52 176.5 0.6 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF1971 PF09313.11 AII58417.1 - 0.028 14.4 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1971) Trp_syntA PF00290.20 AII58418.1 - 6.3e-86 287.4 0.2 8.1e-86 287.1 0.2 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PcrB PF01884.17 AII58418.1 - 0.00085 18.8 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 PcrB family His_biosynth PF00977.21 AII58418.1 - 0.0089 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein BtpA PF03437.15 AII58418.1 - 0.061 12.8 0.0 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 BtpA family AA_permease_2 PF13520.6 AII58419.1 - 0.00097 18.1 2.0 0.0011 17.9 2.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1418 PF07214.12 AII58419.1 - 0.011 15.6 0.4 0.019 14.8 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) SurA_N_2 PF13623.6 AII58419.1 - 0.07 13.0 0.6 0.07 13.0 0.6 1.7 2 0 0 2 2 2 0 SurA N-terminal domain SLATT_6 PF18169.1 AII58419.1 - 0.08 12.5 0.2 0.095 12.3 0.2 1.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 ABC2_membrane_5 PF13346.6 AII58419.1 - 0.14 11.7 4.2 0.62 9.6 4.2 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein Tetraspanin PF00335.20 AII58419.1 - 1.3 8.7 4.0 1.7 8.3 4.0 1.3 1 0 0 1 1 1 0 Tetraspanin family DUF2892 PF11127.8 AII58419.1 - 1.9 8.6 7.2 1.1 9.4 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) DUF202 PF02656.15 AII58419.1 - 3.4 8.2 7.6 0.2 12.1 2.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF2207 PF09972.9 AII58419.1 - 6.9 5.3 5.3 7.9 5.1 5.3 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Dehalogenase PF13486.6 AII58420.1 - 5.9e-78 262.2 0.0 7.6e-78 261.8 0.0 1.1 1 0 0 1 1 1 1 Reductive dehalogenase subunit Fer4_16 PF13484.6 AII58420.1 - 2.6e-11 44.3 6.6 4.8e-11 43.4 6.6 1.5 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain TAT_signal PF10518.9 AII58420.1 - 1e-05 25.1 5.7 2.4e-05 24.0 5.7 1.6 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence Fer4_7 PF12838.7 AII58420.1 - 1.3e-05 25.7 6.6 2.6e-05 24.7 6.6 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 AII58420.1 - 4.9e-05 23.7 1.4 0.21 12.0 0.5 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AII58420.1 - 5e-05 23.4 3.5 0.009 16.2 0.2 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 AII58420.1 - 0.00065 19.4 11.5 0.0037 17.0 2.8 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 AII58420.1 - 0.00088 19.8 1.4 0.46 11.1 0.1 2.8 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 AII58420.1 - 0.07 13.7 11.1 1.9 9.2 0.9 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.7 AII58420.1 - 0.077 13.1 12.4 0.44 10.7 4.4 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 AII58420.1 - 0.16 13.0 13.8 2.7 9.1 6.3 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_10 PF13237.6 AII58420.1 - 0.2 11.8 13.0 1.7 8.8 13.4 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 AII58420.1 - 0.35 11.0 6.6 0.66 10.1 1.6 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain MarR_2 PF12802.7 AII58421.1 - 3.1e-08 33.4 0.0 5.5e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 MarR family MarR PF01047.22 AII58421.1 - 4e-06 26.7 0.2 1.7e-05 24.6 0.1 2.1 1 1 1 2 2 2 1 MarR family HTH_27 PF13463.6 AII58421.1 - 1.1e-05 25.8 0.2 2.1e-05 24.9 0.2 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain Fe_dep_repress PF01325.19 AII58421.1 - 0.0022 18.2 0.0 0.029 14.6 0.0 2.3 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain HTH_20 PF12840.7 AII58421.1 - 0.0029 17.6 0.1 0.011 15.8 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain TrmB PF01978.19 AII58421.1 - 0.0032 17.3 0.0 0.0071 16.2 0.0 1.7 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB LexA_DNA_bind PF01726.16 AII58421.1 - 0.011 15.4 0.1 0.043 13.6 0.1 2.1 1 1 1 2 2 2 0 LexA DNA binding domain Penicillinase_R PF03965.16 AII58421.1 - 0.038 14.3 0.5 0.085 13.2 0.4 1.8 1 1 0 1 1 1 0 Penicillinase repressor Phage_rep_org_N PF09681.10 AII58421.1 - 0.049 13.6 2.3 0.28 11.1 0.2 2.1 1 1 1 2 2 2 0 N-terminal phage replisome organiser (Phage_rep_org_N) Thy1 PF02511.15 AII58422.1 - 1.7e-61 207.4 0.2 1.9e-61 207.2 0.2 1.0 1 0 0 1 1 1 1 Thymidylate synthase complementing protein ABC_tran PF00005.27 AII58423.1 - 2.8e-30 105.6 0.0 3.8e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 AII58423.1 - 5.3e-05 23.7 2.5 0.0006 20.3 2.5 2.3 1 1 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region AAA_21 PF13304.6 AII58423.1 - 0.00021 21.2 1.5 0.044 13.6 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 AII58423.1 - 0.00021 21.7 0.0 0.00031 21.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 AII58423.1 - 0.0014 19.1 0.1 0.0025 18.2 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AII58423.1 - 0.0022 18.3 0.0 0.0046 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 AII58423.1 - 0.0028 17.4 0.1 0.005 16.6 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 AII58423.1 - 0.0051 16.3 0.0 0.0083 15.6 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_5 PF07728.14 AII58423.1 - 0.012 15.6 0.1 0.036 14.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 AII58423.1 - 0.017 14.4 0.1 0.027 13.7 0.1 1.4 1 1 0 1 1 1 0 Zeta toxin AAA_23 PF13476.6 AII58423.1 - 0.017 15.6 0.0 0.024 15.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AII58423.1 - 0.02 14.8 0.1 0.048 13.6 0.1 1.6 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 AII58423.1 - 0.021 14.7 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 AII58423.1 - 0.03 14.3 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_15 PF13175.6 AII58423.1 - 0.033 13.9 0.0 0.042 13.6 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 AII58423.1 - 0.056 13.6 0.0 0.078 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AII58423.1 - 0.061 13.9 0.0 0.1 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 AII58423.1 - 0.079 12.4 0.2 0.24 10.8 0.1 1.8 2 0 0 2 2 2 0 PhoH-like protein MobB PF03205.14 AII58423.1 - 0.083 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.22 AII58423.1 - 0.089 12.0 0.2 0.15 11.2 0.2 1.3 1 0 0 1 1 1 0 NB-ARC domain Mg_chelatase PF01078.21 AII58423.1 - 0.095 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.23 AII58423.1 - 0.097 12.8 0.1 0.27 11.4 0.1 1.7 1 1 1 2 2 2 0 50S ribosome-binding GTPase PRK PF00485.18 AII58423.1 - 0.099 12.4 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family IstB_IS21 PF01695.17 AII58423.1 - 0.11 12.3 0.3 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein PduV-EutP PF10662.9 AII58423.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RNA_pol_Rpb1_3 PF04983.18 AII58423.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 3 AAA_24 PF13479.6 AII58423.1 - 0.19 11.4 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 AII58423.1 - 0.2 10.8 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit ABC_tran PF00005.27 AII58424.1 - 1.6e-23 83.7 0.0 2.3e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter oligo_HPY PF08352.12 AII58424.1 - 1.3e-10 41.6 0.0 2.5e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Oligopeptide/dipeptide transporter, C-terminal region SMC_N PF02463.19 AII58424.1 - 2.6e-05 23.8 0.1 0.00027 20.4 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 AII58424.1 - 0.00084 19.2 1.3 0.023 14.5 0.3 2.1 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 AII58424.1 - 0.012 15.1 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 AII58424.1 - 0.043 14.2 0.2 0.066 13.6 0.2 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 AII58424.1 - 0.082 13.2 0.6 0.54 10.5 0.6 2.1 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 AII58424.1 - 0.16 11.9 0.1 0.6 10.0 0.0 1.9 2 0 0 2 2 2 0 NACHT domain BPD_transp_1 PF00528.22 AII58425.1 - 7.3e-31 107.3 11.0 7.3e-31 107.3 11.0 2.0 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component OppC_N PF12911.7 AII58425.1 - 7.3e-05 22.7 0.6 7.3e-05 22.7 0.6 3.7 4 0 0 4 4 4 1 N-terminal TM domain of oligopeptide transport permease C BPD_transp_1 PF00528.22 AII58426.1 - 6.3e-40 136.9 19.1 6.3e-40 136.9 19.1 1.9 2 1 1 3 3 3 1 Binding-protein-dependent transport system inner membrane component SBP_bac_5 PF00496.22 AII58427.1 - 1.8e-75 254.3 1.5 2.3e-75 253.9 1.5 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Methyltransf_25 PF13649.6 AII58428.1 - 3.5e-08 34.0 0.0 6.9e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AII58428.1 - 4.3e-08 33.2 0.0 7e-08 32.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 AII58428.1 - 9.3e-07 28.3 0.0 1.4e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_11 PF08241.12 AII58428.1 - 1.5e-06 28.8 0.0 2.5e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 AII58428.1 - 4e-06 26.7 0.0 6.6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_12 PF08242.12 AII58428.1 - 4.1e-06 27.5 0.0 1.1e-05 26.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 AII58428.1 - 9.9e-05 21.9 0.0 0.00026 20.5 0.0 1.7 1 1 1 2 2 2 1 Putative methyltransferase Methyltransf_31 PF13847.6 AII58428.1 - 0.00018 21.3 0.0 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 AII58428.1 - 0.0004 19.8 0.0 0.00059 19.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.14 AII58428.1 - 0.0039 16.6 0.0 0.0053 16.2 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB tRNA_U5-meth_tr PF05958.11 AII58428.1 - 0.0094 15.0 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase MTS PF05175.14 AII58428.1 - 0.022 14.3 0.0 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.20 AII58428.1 - 0.037 13.1 0.0 0.057 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF938 PF06080.12 AII58428.1 - 0.12 12.1 0.0 0.32 10.7 0.0 1.7 1 1 0 2 2 2 0 Protein of unknown function (DUF938) Penicillinase_R PF03965.16 AII58429.1 - 1.5e-05 25.3 0.0 2.1e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Penicillinase repressor MarR PF01047.22 AII58429.1 - 0.0033 17.3 0.1 0.0058 16.5 0.1 1.4 1 0 0 1 1 1 1 MarR family PaaX PF07848.12 AII58429.1 - 0.02 15.1 0.0 0.039 14.2 0.0 1.5 1 0 0 1 1 1 0 PaaX-like protein TrmB PF01978.19 AII58429.1 - 0.027 14.3 0.1 0.052 13.4 0.1 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 AII58429.1 - 0.077 13.3 0.2 0.1 12.9 0.2 1.2 1 0 0 1 1 1 0 Transcriptional regulator DUF3725 PF12523.8 AII58429.1 - 0.087 13.1 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3725) FeoC PF09012.10 AII58429.1 - 0.098 12.7 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 FeoC like transcriptional regulator CRCB PF02537.15 AII58430.1 - 1.5e-25 89.3 10.4 1.9e-25 89.0 10.4 1.1 1 0 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) COX15-CtaA PF02628.15 AII58430.1 - 0.0024 17.0 1.7 0.0025 16.9 1.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein HTH_24 PF13412.6 AII58431.1 - 2.8e-06 26.8 0.0 5.3e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 AII58431.1 - 5e-05 23.1 0.0 9.6e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 MarR family MarR PF01047.22 AII58431.1 - 5.7e-05 23.0 0.1 0.0001 22.2 0.1 1.3 1 0 0 1 1 1 1 MarR family HTH_11 PF08279.12 AII58431.1 - 8.8e-05 22.4 0.1 0.00022 21.1 0.1 1.8 1 0 0 1 1 1 1 HTH domain HTH_Crp_2 PF13545.6 AII58431.1 - 0.0036 17.2 0.1 0.01 15.8 0.1 1.8 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_1 PF00126.27 AII58431.1 - 0.004 17.1 0.0 0.008 16.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_13 PF11972.8 AII58431.1 - 0.0052 16.8 0.0 0.039 14.0 0.0 2.4 2 0 0 2 2 2 1 HTH DNA binding domain DUF2190 PF09956.9 AII58431.1 - 0.061 13.8 0.5 0.16 12.5 0.5 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2190) Rrf2 PF02082.20 AII58431.1 - 0.093 13.1 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator HTH_23 PF13384.6 AII58431.1 - 0.1 12.4 0.1 0.27 11.1 0.0 1.8 2 0 0 2 2 2 0 Homeodomain-like domain GyrI-like PF06445.15 AII58432.1 - 1.5e-13 51.3 0.1 2.6e-13 50.6 0.1 1.4 1 1 0 1 1 1 1 GyrI-like small molecule binding domain Cass2 PF14526.6 AII58432.1 - 0.02 15.1 0.2 0.97 9.6 0.0 2.1 1 1 1 2 2 2 0 Integron-associated effector binding protein MFS_1 PF07690.16 AII58433.1 - 5.1e-56 190.1 49.4 5.1e-56 190.1 49.4 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 AII58433.1 - 8.6e-11 41.4 14.5 8.6e-11 41.4 14.5 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.6 AII58433.1 - 3.9e-08 32.3 32.1 2.1e-07 29.9 16.5 2.7 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 AII58433.1 - 5.8e-08 32.0 21.5 1.1e-05 24.5 7.7 2.7 2 1 0 2 2 2 2 MFS_1 like family MFS_4 PF06779.14 AII58433.1 - 9.4e-05 21.9 7.5 9.4e-05 21.9 7.5 2.6 1 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 AII58433.1 - 0.00042 18.9 14.7 0.0026 16.2 6.2 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector UNC-93 PF05978.16 AII58433.1 - 0.087 12.5 13.2 0.2 11.4 2.2 3.4 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 Tetraspanin PF00335.20 AII58433.1 - 0.17 11.6 2.7 0.55 9.9 2.7 1.9 1 0 0 1 1 1 0 Tetraspanin family FeoB_N PF02421.18 AII58434.1 - 2.1e-49 167.1 0.2 3.1e-49 166.5 0.2 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Gate PF07670.14 AII58434.1 - 4.6e-27 94.5 19.1 1.2e-14 54.6 3.3 3.3 3 0 0 3 3 3 2 Nucleoside recognition MMR_HSR1 PF01926.23 AII58434.1 - 8.3e-14 51.6 0.1 1.4e-13 50.9 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_C PF07664.12 AII58434.1 - 5.8e-08 32.3 2.5 5.8e-08 32.3 2.5 3.1 3 0 0 3 3 3 1 Ferrous iron transport protein B C terminus SRPRB PF09439.10 AII58434.1 - 0.024 14.1 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MotA_ExbB PF01618.16 AII58434.1 - 0.052 13.3 0.8 2.3 8.0 0.0 2.5 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family Peptidase_U4 PF03419.13 AII58434.1 - 5.4 6.2 8.0 0.2 10.9 1.0 2.0 2 0 0 2 2 2 0 Sporulation factor SpoIIGA FeoA PF04023.14 AII58435.1 - 1.1e-18 67.2 0.1 1.3e-18 67.0 0.1 1.1 1 0 0 1 1 1 1 FeoA domain FUR PF01475.19 AII58436.1 - 1.4e-32 112.3 0.1 1.6e-32 112.2 0.1 1.0 1 0 0 1 1 1 1 Ferric uptake regulator family PadR PF03551.14 AII58436.1 - 8.9e-06 25.6 0.8 1.3e-05 25.1 0.8 1.2 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_20 PF12840.7 AII58436.1 - 0.00021 21.3 0.0 0.00033 20.7 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 AII58436.1 - 0.0027 17.6 0.1 0.01 15.7 0.1 1.8 1 1 0 1 1 1 1 HTH domain HTH_47 PF16221.5 AII58436.1 - 0.0089 15.6 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 winged helix-turn-helix DUF1495 PF07381.11 AII58436.1 - 0.013 15.3 0.3 0.035 13.9 0.3 1.7 1 1 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) TrmB PF01978.19 AII58436.1 - 0.022 14.6 0.1 0.057 13.3 0.1 1.8 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_12 PF08461.10 AII58436.1 - 0.022 14.7 0.5 0.04 13.9 0.1 1.6 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain HTH_5 PF01022.20 AII58436.1 - 0.025 14.5 0.0 0.052 13.4 0.0 1.7 1 1 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 AII58436.1 - 0.026 14.1 0.1 0.27 10.8 0.1 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding DUF2513 PF10711.9 AII58436.1 - 0.056 13.7 0.1 0.083 13.2 0.1 1.2 1 0 0 1 1 1 0 Hypothetical protein (DUF2513) DUF3874 PF12990.7 AII58436.1 - 0.1 13.0 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknonw function from B. Theta Gene description (DUF3874) SmpB PF01668.18 AII58437.1 - 1.1e-57 194.0 0.8 1.2e-57 193.8 0.8 1.0 1 0 0 1 1 1 1 SmpB protein Resolvase PF00239.21 AII58439.1 - 1.6e-15 57.5 0.0 2.8e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_28 PF13518.6 AII58439.1 - 0.00052 20.1 1.6 0.0017 18.5 0.2 2.4 3 0 0 3 3 3 1 Helix-turn-helix domain NUMOD1 PF07453.13 AII58439.1 - 0.0045 17.2 0.1 4.2 7.7 0.0 2.4 2 0 0 2 2 2 2 NUMOD1 domain HTH_Tnp_ISL3 PF13542.6 AII58439.1 - 0.0079 15.6 0.0 0.018 14.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 AII58439.1 - 0.011 15.5 0.9 0.025 14.3 0.2 1.9 2 0 0 2 2 2 0 Homeodomain-like domain HTH_7 PF02796.15 AII58439.1 - 0.013 15.6 0.1 0.031 14.3 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_psq PF05225.16 AII58439.1 - 0.026 14.3 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 helix-turn-helix, Psq domain RWP-RK PF02042.15 AII58439.1 - 0.046 13.7 0.2 0.27 11.2 0.0 2.3 3 0 0 3 3 3 0 RWP-RK domain SinI PF08671.10 AII58439.1 - 0.052 13.3 0.7 3.9 7.3 0.0 3.1 3 0 0 3 3 3 0 Anti-repressor SinI AbiEi_4 PF13338.6 AII58439.1 - 0.076 13.2 0.3 0.21 11.7 0.3 1.8 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin DUF2089 PF09862.9 AII58439.1 - 0.086 12.9 0.1 0.55 10.3 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2089) HTH_17 PF12728.7 AII58439.1 - 0.14 12.4 0.4 0.62 10.3 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_8 PF02954.19 AII58439.1 - 1.2 8.9 4.3 0.61 9.9 1.1 2.1 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family HTH_33 PF13592.6 AII58440.1 - 0.054 13.2 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix Ku_C PF03730.14 AII58440.1 - 0.11 13.2 0.1 0.17 12.6 0.1 1.3 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm ParBc PF02195.18 AII58442.1 - 4.5e-12 46.1 0.0 8.1e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 ParB-like nuclease domain DUF3631 PF12307.8 AII58443.1 - 2.3e-49 168.1 0.2 4e-49 167.3 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3631) Toprim_4 PF13662.6 AII58443.1 - 0.073 13.5 0.0 0.21 12.1 0.0 1.8 1 0 0 1 1 1 0 Toprim domain Toprim_2 PF13155.6 AII58443.1 - 0.1 13.1 0.0 0.29 11.6 0.0 1.8 1 0 0 1 1 1 0 Toprim-like Polbeta PF18765.1 AII58444.1 - 5.8e-09 35.9 0.4 1.1e-08 35.1 0.4 1.5 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 AII58444.1 - 3.8e-07 30.3 0.1 7.5e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain HTH_24 PF13412.6 AII58444.1 - 0.013 15.1 0.1 0.025 14.2 0.1 1.5 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 AII58444.1 - 0.054 13.6 0.0 0.094 12.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_5 PF01022.20 AII58444.1 - 0.06 13.2 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family TrmB PF01978.19 AII58444.1 - 0.065 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB PAP2_C PF14360.6 AII58445.1 - 0.036 14.6 0.7 0.036 14.6 0.7 1.9 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Bax1-I PF01027.20 AII58445.1 - 0.064 13.1 5.7 0.072 12.9 5.7 1.0 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Glucos_trans_II PF14264.6 AII58445.1 - 0.092 12.1 8.5 0.034 13.5 2.4 1.9 1 1 1 2 2 2 0 Glucosyl transferase GtrII DUF3180 PF11377.8 AII58445.1 - 0.17 12.0 5.8 0.31 11.2 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) DUF2976 PF11190.8 AII58445.1 - 1.7 8.5 9.4 4 7.3 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Tetraspanin PF00335.20 AII58445.1 - 3 7.5 6.7 3.4 7.3 6.7 1.0 1 0 0 1 1 1 0 Tetraspanin family DUF4131 PF13567.6 AII58445.1 - 7.8 6.1 9.9 50 3.5 9.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Dehalogenase PF13486.6 AII58446.1 - 1.2e-88 297.3 0.5 1.6e-88 296.9 0.5 1.2 1 0 0 1 1 1 1 Reductive dehalogenase subunit Fer4_16 PF13484.6 AII58446.1 - 5.4e-08 33.6 8.1 1.6e-07 32.2 8.1 1.8 1 1 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4 PF00037.27 AII58446.1 - 7.9e-08 31.8 11.5 7e-05 22.5 3.0 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 AII58446.1 - 4.1e-07 30.1 1.0 0.005 17.0 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AII58446.1 - 5.2e-07 30.2 7.6 1.2e-06 29.0 7.6 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AII58446.1 - 1.2e-06 28.5 3.6 0.0065 16.6 0.1 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AII58446.1 - 5.2e-05 23.6 3.2 0.17 12.3 0.5 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AII58446.1 - 0.00069 19.6 11.0 0.05 13.7 2.2 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 AII58446.1 - 0.00069 19.6 13.4 0.029 14.5 2.1 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain TAT_signal PF10518.9 AII58446.1 - 0.0035 17.1 3.7 0.0035 17.1 3.7 2.3 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence Fer4_17 PF13534.6 AII58446.1 - 0.0076 16.8 9.7 0.39 11.3 10.8 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 AII58446.1 - 0.009 16.1 8.4 0.76 9.9 1.3 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 AII58446.1 - 1.8 9.3 16.9 0.21 12.2 4.2 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 AII58446.1 - 8.8 6.6 6.3 35 4.6 0.9 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Response_reg PF00072.24 AII58447.1 - 2.9e-24 85.4 0.1 5e-24 84.6 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AII58447.1 - 9.7e-18 64.0 0.0 1.9e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal G3P_antiterm PF04309.12 AII58447.1 - 0.025 14.0 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator AA_permease_2 PF13520.6 AII58448.1 - 0.014 14.3 7.4 0.02 13.8 7.3 1.3 1 1 0 1 1 1 0 Amino acid permease DUF202 PF02656.15 AII58448.1 - 0.023 15.1 4.8 0.023 15.1 4.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Glucos_trans_II PF14264.6 AII58448.1 - 0.03 13.7 3.6 0.032 13.6 3.2 1.3 1 1 0 1 1 1 0 Glucosyl transferase GtrII TssN PF17555.2 AII58448.1 - 0.065 12.6 1.3 0.077 12.4 1.3 1.0 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF4605 PF15378.6 AII58448.1 - 0.13 12.1 0.1 0.13 12.1 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4605) LptF_LptG PF03739.14 AII58448.1 - 0.34 9.7 10.1 0.37 9.6 10.1 1.0 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG EamA PF00892.20 AII58448.1 - 0.4 10.8 10.7 0.66 10.2 10.7 1.4 1 0 0 1 1 1 0 EamA-like transporter family CPP1-like PF11833.8 AII58448.1 - 0.5 10.0 5.3 0.6 9.7 5.3 1.1 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Saf_2TM PF18303.1 AII58448.1 - 1.1 8.8 8.8 3.1 7.4 0.1 2.2 1 1 0 2 2 2 0 SAVED-fused 2TM effector domain Tetraspanin PF00335.20 AII58448.1 - 2.8 7.6 5.6 3.4 7.3 5.6 1.1 1 0 0 1 1 1 0 Tetraspanin family Wzy_C PF04932.15 AII58448.1 - 5.5 6.6 8.3 13 5.4 8.3 1.7 1 1 0 1 1 1 0 O-Antigen ligase DUF4131 PF13567.6 AII58448.1 - 8.1 6.1 15.4 0.57 9.8 5.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) CcmH PF03918.14 AII58448.1 - 8.3 5.7 5.8 1.3 8.3 0.4 2.1 1 1 0 2 2 2 0 Cytochrome C biogenesis protein Dehalogenase PF13486.6 AII58449.1 - 1.2e-58 198.8 0.0 1.6e-58 198.4 0.0 1.2 1 0 0 1 1 1 1 Reductive dehalogenase subunit Fer4_16 PF13484.6 AII58449.1 - 4.4e-12 46.7 9.7 9.3e-12 45.7 9.7 1.6 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain TAT_signal PF10518.9 AII58449.1 - 0.00068 19.4 2.2 0.00068 19.4 2.2 2.3 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence Fer4_9 PF13187.6 AII58449.1 - 0.002 18.2 10.0 0.035 14.3 4.5 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AII58449.1 - 0.0048 17.5 10.8 0.012 16.2 10.8 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 AII58449.1 - 0.0078 16.7 5.4 0.36 11.4 2.7 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4 PF00037.27 AII58449.1 - 0.0078 16.0 4.5 0.0078 16.0 4.5 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_10 PF13237.6 AII58449.1 - 0.017 15.2 8.2 0.075 13.2 2.9 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 AII58449.1 - 0.21 11.7 10.7 1 9.5 4.5 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 AII58449.1 - 0.56 10.7 11.3 23 5.5 0.0 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain ABC2_membrane PF01061.24 AII58450.1 - 0.017 14.6 11.7 0.019 14.4 11.7 1.1 1 0 0 1 1 1 0 ABC-2 type transporter Tetraspanin PF00335.20 AII58450.1 - 0.036 13.8 8.8 0.037 13.7 8.8 1.0 1 0 0 1 1 1 0 Tetraspanin family OATP PF03137.20 AII58450.1 - 0.088 11.1 0.8 0.092 11.0 0.8 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family ABC2_membrane_5 PF13346.6 AII58450.1 - 0.23 11.0 6.0 0.45 10.0 6.0 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein Corona_S2 PF01601.16 AII58450.1 - 0.35 9.3 1.1 0.41 9.1 1.1 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DUF2070 PF09843.9 AII58450.1 - 0.58 8.4 1.7 0.56 8.4 1.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) SieB PF14163.6 AII58450.1 - 6.3 6.3 8.4 8.9 5.8 0.2 2.0 1 1 1 2 2 2 0 Super-infection exclusion protein B Dehalogenase PF13486.6 AII58451.1 - 3.2e-60 204.0 0.1 4.1e-60 203.6 0.1 1.1 1 0 0 1 1 1 1 Reductive dehalogenase subunit Fer4_16 PF13484.6 AII58451.1 - 5.3e-08 33.7 7.0 1.2e-07 32.6 7.0 1.6 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4 PF00037.27 AII58451.1 - 0.00031 20.4 4.6 0.00031 20.4 4.6 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_9 PF13187.6 AII58451.1 - 0.00032 20.8 9.3 0.00079 19.5 9.3 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AII58451.1 - 0.00071 20.1 7.8 0.0019 18.7 7.8 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 AII58451.1 - 0.0082 16.6 7.1 0.02 15.3 7.1 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain UCR_Fe-S_N PF10399.9 AII58451.1 - 0.009 15.3 0.2 0.018 14.4 0.2 1.5 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal TAT_signal PF10518.9 AII58451.1 - 0.011 15.6 3.2 0.011 15.6 3.2 2.2 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence Fer4_10 PF13237.6 AII58451.1 - 0.017 15.3 12.1 0.29 11.3 13.5 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 AII58451.1 - 0.32 11.6 9.0 1.3 9.6 9.1 2.0 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 AII58451.1 - 0.48 10.6 14.8 1.6 9.0 3.9 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Response_reg PF00072.24 AII58452.1 - 7.3e-24 84.1 0.1 1.1e-23 83.6 0.1 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AII58452.1 - 2.3e-17 62.9 0.0 4.2e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal GerE PF00196.19 AII58452.1 - 0.027 14.0 0.0 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family DUF2207 PF09972.9 AII58453.1 - 0.51 9.1 2.6 0.53 9.0 2.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4131 PF13567.6 AII58453.1 - 5.7 6.6 9.9 1.9 8.1 7.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Dehalogenase PF13486.6 AII58454.1 - 9.8e-87 291.0 0.2 1.3e-86 290.5 0.2 1.2 1 0 0 1 1 1 1 Reductive dehalogenase subunit Fer4_7 PF12838.7 AII58454.1 - 5.4e-07 30.1 6.9 1.1e-06 29.1 6.9 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AII58454.1 - 2.7e-05 24.2 2.7 0.022 14.9 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AII58454.1 - 8.1e-05 22.7 6.3 0.00017 21.7 6.3 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain TAT_signal PF10518.9 AII58454.1 - 8.3e-05 22.3 5.2 0.00017 21.3 5.2 1.6 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence Fer4_8 PF13183.6 AII58454.1 - 0.00025 21.4 2.7 0.076 13.5 0.1 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AII58454.1 - 0.00056 20.8 10.8 0.0035 18.2 10.8 2.2 1 1 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4 PF00037.27 AII58454.1 - 0.0007 19.3 9.8 0.0018 18.0 1.6 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 AII58454.1 - 0.07 13.3 6.6 0.22 11.7 6.6 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 AII58454.1 - 0.31 11.2 9.0 0.31 11.2 1.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_2 PF12797.7 AII58454.1 - 1 9.6 9.8 1.2 9.3 1.5 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 AII58454.1 - 8.9 6.9 12.0 66 4.2 12.1 2.2 1 1 0 1 1 1 0 4Fe-4S dicluster domain SurA_N_2 PF13623.6 AII58455.1 - 0.057 13.3 0.5 0.057 13.3 0.5 1.8 1 1 1 2 2 2 0 SurA N-terminal domain Glucos_trans_II PF14264.6 AII58455.1 - 0.36 10.2 7.5 0.4 10.0 7.5 1.1 1 0 0 1 1 1 0 Glucosyl transferase GtrII ABC2_membrane_5 PF13346.6 AII58455.1 - 0.41 10.2 5.9 0.87 9.1 5.9 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein TssN PF17555.2 AII58455.1 - 0.75 9.1 5.8 0.83 9.0 5.8 1.0 1 0 0 1 1 1 0 Type VI secretion system, TssN FtsX PF02687.21 AII58455.1 - 1.1 9.8 11.5 4.9 7.7 11.5 1.9 1 1 0 1 1 1 0 FtsX-like permease family SfLAP PF11139.8 AII58455.1 - 5 6.5 12.7 18 4.7 12.7 1.8 1 1 0 1 1 1 0 Sap, sulfolipid-1-addressing protein Tetraspanin PF00335.20 AII58455.1 - 5.2 6.7 8.7 5.9 6.5 8.7 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF1418 PF07214.12 AII58455.1 - 5.8 6.9 5.9 2.1 8.3 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1418) Phage_holin_3_6 PF07332.11 AII58455.1 - 7.3 6.7 16.6 1.5e+02 2.5 16.6 2.0 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4133 PF13571.6 AII58455.1 - 8.7 6.8 6.9 13 6.2 3.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4133) TMEM100 PF16311.5 AII58455.1 - 9.4 5.8 6.3 8.3 6.0 1.4 2.0 1 1 1 2 2 2 0 Transmembrane protein 100 Dehalogenase PF13486.6 AII58456.1 - 1.7e-48 165.5 0.1 2.3e-47 161.8 0.1 2.2 1 1 0 1 1 1 1 Reductive dehalogenase subunit Fer4_16 PF13484.6 AII58456.1 - 5.7e-08 33.6 8.1 1.1e-07 32.7 8.1 1.5 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_8 PF13183.6 AII58456.1 - 5.5e-05 23.5 1.6 0.1 13.0 0.4 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AII58456.1 - 5.9e-05 23.6 8.3 0.00014 22.4 8.3 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AII58456.1 - 0.00016 21.8 4.4 0.13 12.4 0.2 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AII58456.1 - 0.001 19.1 6.5 0.37 10.9 0.2 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 AII58456.1 - 0.0013 18.4 10.4 0.62 10.0 6.5 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 AII58456.1 - 0.0061 17.1 8.1 0.073 13.6 9.0 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 AII58456.1 - 0.28 11.4 8.4 2.3 8.4 3.5 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 AII58456.1 - 9.8 6.5 16.0 4.7 7.5 1.1 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain HTH_Tnp_1 PF01527.20 AII58457.1 - 3.8e-19 68.8 0.4 4.5e-19 68.5 0.4 1.1 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 AII58457.1 - 9.4e-07 28.5 0.0 2.1e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 AII58457.1 - 5.8e-06 26.2 0.0 8e-06 25.8 0.0 1.4 1 1 0 1 1 1 1 Winged helix-turn helix HTH_18 PF12833.7 AII58457.1 - 2.1e-05 24.7 0.0 0.0064 16.7 0.0 1.6 1 1 1 2 2 2 2 Helix-turn-helix domain HTH_28 PF13518.6 AII58457.1 - 3.2e-05 24.0 0.0 7.7e-05 22.7 0.0 1.6 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_Tnp_1_2 PF13022.6 AII58457.1 - 0.0012 19.0 0.9 0.0039 17.3 0.9 1.8 1 1 0 1 1 1 1 Helix-turn-helix of insertion element transposase Terminase_5 PF06056.12 AII58457.1 - 0.0067 16.3 0.0 0.0097 15.8 0.0 1.3 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) CENP-B_N PF04218.13 AII58457.1 - 0.019 14.6 0.1 0.2 11.3 0.0 2.0 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain HTH_7 PF02796.15 AII58457.1 - 0.027 14.5 0.0 0.063 13.4 0.0 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain of resolvase DivIC PF04977.15 AII58457.1 - 0.16 11.8 2.4 0.22 11.3 2.4 1.3 1 0 0 1 1 1 0 Septum formation initiator rve_3 PF13683.6 AII58458.1 - 2.1e-26 91.4 0.2 9.4e-26 89.4 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain rve PF00665.26 AII58458.1 - 1.2e-22 80.3 0.0 2.2e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 AII58458.1 - 1.2e-12 47.7 8.1 2.3e-12 46.8 8.1 1.5 1 0 0 1 1 1 1 HTH-like domain rve_2 PF13333.6 AII58458.1 - 9.6e-05 22.5 0.0 0.00028 21.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 AII58458.1 - 0.0045 17.2 0.0 0.0071 16.6 0.0 1.4 1 0 0 1 1 1 1 DDE domain DUF1418 PF07214.12 AII58459.1 - 0.31 10.9 2.8 0.49 10.3 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) DUF3290 PF11694.8 AII58459.1 - 0.57 10.2 4.5 0.96 9.4 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3290) Cation_ATPase_C PF00689.21 AII58459.1 - 0.75 9.5 8.8 1 9.1 8.8 1.2 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF202 PF02656.15 AII58459.1 - 8.4 6.9 15.0 13 6.4 4.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF202) DUF2892 PF11127.8 AII58459.1 - 9.8 6.3 14.3 0.17 11.9 5.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2892) Dehalogenase PF13486.6 AII58460.1 - 6.5e-66 222.7 0.0 9.8e-66 222.1 0.0 1.3 1 0 0 1 1 1 1 Reductive dehalogenase subunit Fer4_16 PF13484.6 AII58460.1 - 3.6e-07 31.0 4.6 3.6e-07 31.0 4.6 1.7 2 0 0 2 2 1 1 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 AII58460.1 - 1.8e-05 25.2 3.0 4.2e-05 24.0 3.0 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain TAT_signal PF10518.9 AII58460.1 - 8.9e-05 22.2 3.1 8.9e-05 22.2 3.1 2.8 2 0 0 2 2 1 1 TAT (twin-arginine translocation) pathway signal sequence Fer4_17 PF13534.6 AII58460.1 - 0.028 15.0 2.3 0.46 11.1 0.5 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain UCR_Fe-S_N PF10399.9 AII58460.1 - 0.034 13.5 0.2 0.12 11.7 0.2 1.9 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Fer4_9 PF13187.6 AII58460.1 - 0.063 13.5 9.3 0.32 11.2 2.1 2.3 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4 PF00037.27 AII58460.1 - 0.13 12.1 12.4 0.03 14.1 4.3 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_10 PF13237.6 AII58460.1 - 0.22 11.7 10.9 1.2 9.3 11.5 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 AII58460.1 - 6.3 7.0 16.1 8.8 6.6 5.0 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_2 PF12797.7 AII58460.1 - 7.3 6.9 14.1 0.9 9.8 2.7 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Response_reg PF00072.24 AII58461.1 - 2.1e-24 85.8 0.1 3.3e-24 85.2 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AII58461.1 - 4.2e-17 62.0 0.0 8.7e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Dehalogenase PF13486.6 AII58462.1 - 2.8e-58 197.6 0.1 3.3e-58 197.3 0.1 1.1 1 0 0 1 1 1 1 Reductive dehalogenase subunit Fer4_16 PF13484.6 AII58462.1 - 7.7e-10 39.6 2.9 1.8e-09 38.4 2.9 1.6 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 AII58462.1 - 2.2e-08 34.5 2.4 5.6e-08 33.3 2.4 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 AII58462.1 - 1.3e-06 28.0 11.7 0.0001 22.0 5.0 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 AII58462.1 - 0.00037 20.5 13.0 0.034 14.2 5.5 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 AII58462.1 - 0.0004 20.8 5.6 0.028 14.9 0.2 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AII58462.1 - 0.00096 19.2 6.4 0.037 14.2 0.5 2.6 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 AII58462.1 - 0.0045 17.5 7.1 0.088 13.4 0.2 3.0 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AII58462.1 - 0.013 15.6 8.3 0.055 13.6 2.7 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 AII58462.1 - 0.032 14.3 8.9 0.12 12.5 2.8 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_21 PF14697.6 AII58462.1 - 0.037 14.2 9.5 0.12 12.5 3.6 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 AII58462.1 - 0.29 11.7 10.0 0.48 11.1 2.1 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 AII58462.1 - 0.4 11.7 10.7 5.1 8.3 4.3 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain PalH PF08733.10 AII58463.1 - 0.0012 17.9 3.0 0.0012 17.9 3.0 1.0 1 0 0 1 1 1 1 PalH/RIM21 7TMR-DISM_7TM PF07695.11 AII58463.1 - 0.018 14.9 2.9 0.021 14.7 2.9 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling DUF3180 PF11377.8 AII58463.1 - 0.021 15.0 2.2 0.097 12.8 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) TctA PF01970.16 AII58463.1 - 0.037 12.7 4.2 0.039 12.7 4.2 1.0 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family Bax1-I PF01027.20 AII58463.1 - 0.043 13.6 3.9 0.046 13.6 3.9 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 5TM-5TMR_LYT PF07694.12 AII58463.1 - 0.081 12.4 6.2 0.19 11.3 6.3 1.6 1 1 0 1 1 1 0 5TMR of 5TMR-LYT DUF1129 PF06570.11 AII58463.1 - 0.098 12.1 2.6 0.1 12.0 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF2953 PF11167.8 AII58463.1 - 0.15 12.2 0.9 14 5.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) DUF2085 PF09858.9 AII58463.1 - 0.2 12.1 2.3 0.26 11.8 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2085) Spore_YhaL PF14147.6 AII58463.1 - 0.25 11.1 0.9 0.59 9.9 0.1 2.0 2 0 0 2 2 2 0 Sporulation protein YhaL Keratin_assoc PF09775.9 AII58463.1 - 0.31 10.7 4.3 0.13 11.9 1.8 1.6 1 1 0 2 2 2 0 Keratinocyte-associated protein 2 DUF805 PF05656.14 AII58463.1 - 0.52 10.7 2.4 0.43 11.0 0.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF805) DUF4203 PF13886.6 AII58463.1 - 1.2 8.7 8.6 2.7 7.6 8.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4203) Nucleos_tra2_N PF01773.20 AII58463.1 - 3.4 8.4 7.9 22 5.7 7.9 2.1 1 1 0 1 1 1 0 Na+ dependent nucleoside transporter N-terminus FeoB_C PF07664.12 AII58463.1 - 3.8 7.3 7.7 4.1 7.2 0.1 2.8 2 1 1 3 3 3 0 Ferrous iron transport protein B C terminus DUF3382 PF11862.8 AII58463.1 - 4.1 7.7 8.2 3.6 7.9 0.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3382) Dehalogenase PF13486.6 AII58464.1 - 4.6e-13 49.2 0.0 7.4e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Reductive dehalogenase subunit Fer4_16 PF13484.6 AII58464.1 - 4e-09 37.3 9.3 1e-08 36.0 9.3 1.7 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 AII58464.1 - 1.6e-06 28.6 8.2 1.6e-06 28.6 8.2 1.7 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AII58464.1 - 0.015 15.4 11.7 0.48 10.6 13.1 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 AII58464.1 - 0.037 14.1 13.7 0.11 12.6 3.4 3.0 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_2 PF12797.7 AII58464.1 - 0.068 13.3 8.8 0.96 9.7 1.3 2.8 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_9 PF13187.6 AII58464.1 - 0.071 13.3 10.0 0.45 10.7 10.1 2.3 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4 PF00037.27 AII58464.1 - 0.23 11.4 13.4 0.059 13.2 2.3 2.9 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_21 PF14697.6 AII58464.1 - 0.59 10.3 11.5 5.1 7.3 3.1 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 AII58464.1 - 5.7 7.7 8.9 4.8 7.9 0.5 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain MerR_1 PF13411.6 AII58465.1 - 5.4e-20 71.3 0.6 1.4e-19 69.9 0.2 1.7 2 0 0 2 2 2 1 MerR HTH family regulatory protein MerR PF00376.23 AII58465.1 - 2.2e-12 46.5 0.3 4.5e-12 45.5 0.1 1.7 2 0 0 2 2 2 1 MerR family regulatory protein MerR-DNA-bind PF09278.11 AII58465.1 - 1.3e-05 25.6 0.2 2.1e-05 25.0 0.2 1.3 1 0 0 1 1 1 1 MerR, DNA binding HTH_23 PF13384.6 AII58465.1 - 0.001 18.8 0.0 0.048 13.5 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_17 PF12728.7 AII58465.1 - 0.0099 16.0 0.1 0.023 14.9 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain DUF4116 PF13475.6 AII58465.1 - 0.021 14.5 0.2 0.034 13.9 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4116) GerE PF00196.19 AII58465.1 - 0.079 12.5 0.1 0.54 9.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family NUMOD1 PF07453.13 AII58465.1 - 0.14 12.4 0.0 0.38 11.1 0.0 1.8 1 0 0 1 1 1 0 NUMOD1 domain Dehalogenase PF13486.6 AII58466.1 - 2.4e-76 256.9 0.1 3.2e-76 256.5 0.1 1.2 1 0 0 1 1 1 1 Reductive dehalogenase subunit Fer4_16 PF13484.6 AII58466.1 - 2.7e-12 47.4 5.5 5.8e-12 46.4 5.5 1.6 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 AII58466.1 - 4.5e-06 26.7 6.2 9.1e-06 25.8 6.2 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AII58466.1 - 0.00045 20.8 8.1 0.0018 18.8 8.3 2.0 1 1 0 1 1 1 1 4Fe-4S dicluster domain TAT_signal PF10518.9 AII58466.1 - 0.00053 19.7 0.7 0.0014 18.4 0.7 1.7 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence Fer4_10 PF13237.6 AII58466.1 - 0.0025 17.9 6.9 0.0056 16.8 0.5 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4 PF00037.27 AII58466.1 - 0.003 17.3 3.6 0.003 17.3 3.6 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_2 PF12797.7 AII58466.1 - 0.045 13.9 13.8 0.19 11.9 3.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.6 AII58466.1 - 0.18 12.3 9.3 22 5.6 12.3 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 AII58466.1 - 1.1 9.5 9.0 0.32 11.1 0.5 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 AII58466.1 - 1.5 9.0 16.2 0.12 12.5 5.0 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 AII58466.1 - 4.5 7.9 12.7 2.4 8.8 3.4 2.4 1 1 2 3 3 3 0 4Fe-4S dicluster domain DUF4605 PF15378.6 AII58467.1 - 0.00059 19.6 3.2 0.012 15.5 0.6 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4605) Tetraspanin PF00335.20 AII58467.1 - 0.004 16.9 1.9 0.0044 16.8 1.9 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF2070 PF09843.9 AII58467.1 - 0.066 11.5 0.1 0.08 11.2 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) AA_permease_2 PF13520.6 AII58468.1 - 0.0015 17.4 5.7 0.0018 17.2 5.7 1.2 1 0 0 1 1 1 1 Amino acid permease EamA PF00892.20 AII58468.1 - 0.012 15.8 9.1 0.015 15.5 9.1 1.2 1 0 0 1 1 1 0 EamA-like transporter family Tetraspanin PF00335.20 AII58468.1 - 0.014 15.2 3.5 0.017 14.8 3.5 1.1 1 0 0 1 1 1 0 Tetraspanin family CbiQ PF02361.16 AII58468.1 - 0.022 14.4 6.6 0.028 14.0 6.6 1.2 1 0 0 1 1 1 0 Cobalt transport protein Cytochrom_B_C PF00032.17 AII58468.1 - 0.035 14.4 0.7 0.047 14.0 0.6 1.3 1 1 0 1 1 1 0 Cytochrome b(C-terminal)/b6/petD DUF4131 PF13567.6 AII58468.1 - 0.059 13.0 4.4 0.034 13.8 2.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Rer1 PF03248.13 AII58468.1 - 0.14 11.9 1.7 0.16 11.7 1.1 1.4 1 1 0 1 1 1 0 Rer1 family DUF2985 PF11204.8 AII58468.1 - 0.19 11.9 4.4 0.099 12.8 2.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) DUF4083 PF13314.6 AII58468.1 - 0.34 10.9 0.2 0.34 10.9 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) SurA_N_2 PF13623.6 AII58468.1 - 0.37 10.7 0.1 0.37 10.7 0.1 2.0 1 1 1 2 2 2 0 SurA N-terminal domain CbiZ PF01955.18 AII58469.1 - 2.1e-49 168.3 0.5 2.7e-49 167.9 0.5 1.1 1 0 0 1 1 1 1 Adenosylcobinamide amidohydrolase DUF1418 PF07214.12 AII58470.1 - 0.009 15.9 0.3 0.013 15.4 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1418) DUF2207 PF09972.9 AII58470.1 - 2.8 6.6 6.0 3.1 6.4 6.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Dehalogenase PF13486.6 AII58471.1 - 4.2e-86 288.9 0.0 6e-86 288.4 0.0 1.2 1 0 0 1 1 1 1 Reductive dehalogenase subunit Fer4_16 PF13484.6 AII58471.1 - 1.8e-13 51.2 5.1 3.6e-13 50.2 5.1 1.6 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 AII58471.1 - 7.6e-05 23.2 5.5 0.00016 22.2 5.5 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain TAT_signal PF10518.9 AII58471.1 - 0.00017 21.3 2.9 0.00017 21.3 2.9 1.9 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence Fer4_9 PF13187.6 AII58471.1 - 0.00039 20.5 3.6 0.0066 16.6 0.4 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4 PF00037.27 AII58471.1 - 0.0011 18.7 8.4 0.0013 18.4 1.7 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_8 PF13183.6 AII58471.1 - 0.0042 17.5 1.2 0.11 13.0 0.2 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 AII58471.1 - 0.047 14.2 3.6 0.41 11.2 0.7 2.7 3 0 0 3 3 2 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 AII58471.1 - 0.25 11.5 4.4 0.16 12.1 0.6 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 AII58471.1 - 0.63 10.2 11.0 0.073 13.2 4.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_10 PF13237.6 AII58471.1 - 1.1 9.4 10.8 8.8 6.5 10.8 2.2 1 1 0 1 1 1 0 4Fe-4S dicluster domain Response_reg PF00072.24 AII58472.1 - 5.2e-23 81.3 0.2 8.1e-23 80.7 0.2 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AII58472.1 - 2.1e-17 62.9 0.1 4.3e-17 61.9 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal EcoRII-N PF09217.10 AII58472.1 - 0.098 12.4 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Restriction endonuclease EcoRII, N-terminal Med28 PF11594.8 AII58472.1 - 0.13 12.4 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 28 GerE PF00196.19 AII58473.1 - 4e-09 35.9 0.3 9.5e-09 34.7 0.3 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Trp_repressor PF01371.19 AII58473.1 - 0.00066 19.8 0.3 0.0019 18.3 0.3 1.7 1 0 0 1 1 1 1 Trp repressor protein HTH_40 PF14493.6 AII58473.1 - 0.0012 19.3 1.1 0.0038 17.6 0.1 2.3 2 1 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 AII58473.1 - 0.0072 16.0 0.1 0.021 14.5 0.1 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 AII58473.1 - 0.019 14.8 0.2 0.05 13.5 0.0 1.6 2 0 0 2 2 2 0 ECF sigma factor HTH_38 PF13936.6 AII58473.1 - 0.03 14.1 0.1 0.11 12.3 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain TMPIT PF07851.13 AII58473.1 - 0.037 13.3 0.1 0.061 12.6 0.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein Myb_DNA-bind_6 PF13921.6 AII58473.1 - 0.079 13.2 0.0 23 5.3 0.0 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain PSK_trans_fac PF07704.11 AII58473.1 - 0.63 10.8 3.2 9.9 7.0 0.0 2.6 3 0 0 3 3 3 0 Rv0623-like transcription factor DUF4258 PF14076.6 AII58474.1 - 0.074 13.4 0.4 0.17 12.3 0.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4258) Gln-synt_C PF00120.24 AII58475.1 - 4.9e-55 186.9 0.0 1.8e-54 185.0 0.0 1.8 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 AII58475.1 - 6.5e-12 45.0 0.0 1.2e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Resolvase PF00239.21 AII58476.1 - 1.1e-34 119.6 0.1 1.1e-32 113.1 0.0 2.3 2 0 0 2 2 2 2 Resolvase, N terminal domain Recombinase PF07508.13 AII58476.1 - 2.6e-15 56.7 0.0 7.1e-15 55.3 0.0 1.8 1 0 0 1 1 1 1 Recombinase Zn_ribbon_recom PF13408.6 AII58476.1 - 4.4e-09 36.7 1.4 4.4e-09 36.7 1.4 2.1 2 0 0 2 2 2 1 Recombinase zinc beta ribbon domain RhoGAP PF00620.27 AII58476.1 - 0.095 12.5 0.0 0.51 10.2 0.0 2.2 3 0 0 3 3 3 0 RhoGAP domain Phage_int_SAM_6 PF18644.1 AII58477.1 - 0.12 12.4 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Phage integrase SAM-like domain Resolvase PF00239.21 AII58478.1 - 2.5e-15 56.8 0.0 4e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Resolvase, N terminal domain HTH_7 PF02796.15 AII58478.1 - 0.0014 18.7 0.2 0.0029 17.6 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 AII58478.1 - 0.0032 17.6 0.1 0.009 16.1 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 AII58478.1 - 0.034 14.0 0.1 0.076 12.8 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_psq PF05225.16 AII58478.1 - 0.048 13.4 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HTH_8 PF02954.19 AII58478.1 - 0.077 12.8 0.4 0.26 11.1 0.4 2.0 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family RWP-RK PF02042.15 AII58478.1 - 0.084 12.9 0.0 0.24 11.4 0.0 1.8 1 0 0 1 1 1 0 RWP-RK domain AbiEi_4 PF13338.6 AII58478.1 - 0.09 12.9 0.1 0.25 11.5 0.1 1.8 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin HTH_Tnp_ISL3 PF13542.6 AII58478.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_33 PF13592.6 AII58479.1 - 0.06 13.0 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix TPR_14 PF13428.6 AII58479.1 - 0.099 13.5 0.2 1.9 9.5 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat ParBc PF02195.18 AII58481.1 - 5e-10 39.5 0.0 8.5e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 ParB-like nuclease domain DUF3631 PF12307.8 AII58483.1 - 2.4e-49 168.1 0.1 4e-49 167.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3631) Toprim_4 PF13662.6 AII58483.1 - 0.078 13.5 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 Toprim domain Polbeta PF18765.1 AII58484.1 - 1.4e-09 37.9 0.3 3e-09 36.8 0.3 1.6 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 AII58484.1 - 1.7e-06 28.2 0.1 3.2e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain HTH_5 PF01022.20 AII58484.1 - 0.009 15.9 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 AII58484.1 - 0.057 13.0 0.1 0.12 11.9 0.1 1.6 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_20 PF12840.7 AII58484.1 - 0.094 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain RepL PF05732.11 AII58484.1 - 0.099 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) Diphthami_syn_2 PF01902.17 AII58486.1 - 2.3e-43 148.2 0.0 2.8e-43 148.0 0.0 1.0 1 0 0 1 1 1 1 Diphthamide synthase CutC PF03932.14 AII58486.1 - 0.046 13.2 0.0 0.068 12.6 0.0 1.1 1 0 0 1 1 1 0 CutC family Bax1-I PF01027.20 AII58487.1 - 0.04 13.7 0.7 0.045 13.6 0.7 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 MerC PF03203.14 AII58487.1 - 0.18 12.2 3.3 0.23 11.9 3.3 1.1 1 0 0 1 1 1 0 MerC mercury resistance protein DUF5353 PF17304.2 AII58487.1 - 0.54 10.0 7.1 0.33 10.7 0.9 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5353) DUF4064 PF13273.6 AII58487.1 - 2.1 8.7 6.0 1.9 8.8 2.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF4131 PF13567.6 AII58487.1 - 4.9 6.8 6.5 0.79 9.4 0.8 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4131) Dehalogenase PF13486.6 AII58488.1 - 1.6e-56 191.8 0.1 2.1e-56 191.5 0.1 1.1 1 0 0 1 1 1 1 Reductive dehalogenase subunit Fer4_7 PF12838.7 AII58488.1 - 1.1e-08 35.6 9.0 1.1e-08 35.6 9.0 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 AII58488.1 - 1.5e-08 35.4 10.3 7.3e-08 33.2 10.7 2.0 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4 PF00037.27 AII58488.1 - 9.8e-08 31.5 13.8 8.1e-05 22.3 4.0 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 AII58488.1 - 5.8e-07 29.5 10.1 0.0011 19.0 0.2 3.3 4 0 0 4 4 4 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AII58488.1 - 4.9e-05 23.7 2.3 0.17 12.3 0.1 2.7 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 AII58488.1 - 0.00012 22.5 7.2 0.00035 21.0 7.2 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 AII58488.1 - 0.00024 21.0 11.8 0.029 14.5 1.6 2.8 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 AII58488.1 - 0.00051 20.2 11.7 0.00051 20.2 11.7 2.5 2 1 2 4 4 4 3 4Fe-4S dicluster domain TAT_signal PF10518.9 AII58488.1 - 0.00093 18.9 1.2 0.00093 18.9 1.2 2.0 2 0 0 2 2 1 1 TAT (twin-arginine translocation) pathway signal sequence Fer4_21 PF14697.6 AII58488.1 - 0.022 14.9 14.4 0.23 11.6 11.7 3.0 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 AII58488.1 - 0.12 12.4 20.3 0.16 12.1 4.3 2.8 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_20 PF14691.6 AII58488.1 - 2.5 7.9 6.0 0.47 10.2 0.3 2.3 2 0 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_4 PF12800.7 AII58488.1 - 4.3 8.1 15.9 4.9 7.9 4.7 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_15 PF13459.6 AII58488.1 - 5.2 7.9 7.6 44 4.9 0.1 3.2 3 0 0 3 3 3 0 4Fe-4S single cluster domain CxxCxxCC PF03692.15 AII58489.1 - 3.8e-08 33.9 0.4 8.9e-08 32.7 0.4 1.6 1 1 0 1 1 1 1 Putative zinc- or iron-chelating domain Tim29 PF10171.9 AII58489.1 - 0.025 14.1 0.1 0.033 13.7 0.1 1.2 1 0 0 1 1 1 0 Translocase of the Inner Mitochondrial membrane 29 DUF1965 PF09248.10 AII58489.1 - 0.059 13.2 0.3 0.11 12.3 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) ABC2_membrane_5 PF13346.6 AII58491.1 - 0.0081 15.7 2.6 0.0095 15.5 2.6 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein TssN PF17555.2 AII58491.1 - 0.48 9.8 3.3 0.53 9.6 3.3 1.0 1 0 0 1 1 1 0 Type VI secretion system, TssN Wzy_C PF04932.15 AII58491.1 - 0.8 9.3 5.8 0.41 10.3 3.9 1.4 1 1 0 1 1 1 0 O-Antigen ligase Tetraspanin PF00335.20 AII58491.1 - 2.8 7.6 6.1 5.2 6.7 6.1 1.5 1 1 0 1 1 1 0 Tetraspanin family Dehalogenase PF13486.6 AII58492.1 - 6.9e-71 239.0 0.0 1.1e-70 238.3 0.0 1.3 1 0 0 1 1 1 1 Reductive dehalogenase subunit Fer4_16 PF13484.6 AII58492.1 - 4.5e-09 37.1 8.9 9.2e-09 36.1 8.9 1.6 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 AII58492.1 - 9e-05 23.0 9.2 0.00018 22.0 9.2 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 AII58492.1 - 0.00054 20.3 3.0 0.16 12.4 0.6 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain TAT_signal PF10518.9 AII58492.1 - 0.0025 17.6 6.5 0.012 15.4 6.5 2.3 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence Fer4_10 PF13237.6 AII58492.1 - 0.0066 16.5 7.2 0.078 13.1 0.6 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 AII58492.1 - 0.061 13.2 10.5 0.11 12.3 1.4 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_9 PF13187.6 AII58492.1 - 0.084 13.1 14.9 0.23 11.7 4.2 2.4 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 AII58492.1 - 0.14 12.3 10.8 0.36 11.0 2.6 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_21 PF14697.6 AII58492.1 - 1.2 9.3 7.8 0.59 10.3 0.7 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 AII58492.1 - 5.8 7.5 13.4 5.6 7.6 4.6 2.5 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 AII58492.1 - 9.3 7.0 13.4 3.4 8.4 2.0 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Phage_holin_3_6 PF07332.11 AII58493.1 - 0.087 12.9 6.7 0.47 10.5 6.7 1.9 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4436 PF14494.6 AII58493.1 - 0.096 12.0 0.0 0.14 11.4 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4436) Bax1-I PF01027.20 AII58493.1 - 0.12 12.2 3.4 0.087 12.6 0.6 1.5 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF4149 PF13664.6 AII58493.1 - 0.13 12.6 3.2 0.55 10.6 3.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4149) YwiC PF14256.6 AII58493.1 - 0.15 12.4 4.8 0.19 12.0 4.8 1.1 1 0 0 1 1 1 0 YwiC-like protein DUF4131 PF13567.6 AII58493.1 - 0.37 10.4 7.2 0.072 12.7 2.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF3180 PF11377.8 AII58493.1 - 0.63 10.2 6.7 0.29 11.3 1.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3180) DUF4203 PF13886.6 AII58493.1 - 1 9.0 9.7 1.3 8.6 2.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4203) DUF202 PF02656.15 AII58493.1 - 1.3 9.5 7.3 7.1 7.2 7.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Dehalogenase PF13486.6 AII58494.1 - 3.4e-94 315.5 0.2 4.4e-94 315.1 0.2 1.1 1 0 0 1 1 1 1 Reductive dehalogenase subunit Fer4_16 PF13484.6 AII58494.1 - 1.4e-06 29.1 6.9 2.9e-06 28.1 6.9 1.6 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 AII58494.1 - 4.1e-06 26.8 3.5 0.03 14.4 0.2 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AII58494.1 - 5.2e-06 27.0 7.3 9.7e-06 26.1 7.3 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 AII58494.1 - 0.0011 18.7 2.4 0.0011 18.7 2.4 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain TAT_signal PF10518.9 AII58494.1 - 0.0013 18.5 4.9 0.0013 18.5 4.9 2.4 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence Fer4_17 PF13534.6 AII58494.1 - 0.0023 18.4 6.5 0.0073 16.8 6.7 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AII58494.1 - 0.0031 17.6 8.1 0.085 13.0 9.9 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.7 AII58494.1 - 0.0067 16.5 13.5 0.033 14.3 1.1 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 AII58494.1 - 0.069 13.7 14.7 0.59 10.8 3.2 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain PfkB PF00294.24 AII58494.1 - 0.07 12.4 0.2 0.11 11.8 0.2 1.2 1 0 0 1 1 1 0 pfkB family carbohydrate kinase Fer4_8 PF13183.6 AII58494.1 - 0.18 12.3 10.2 7.3 7.1 11.9 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 AII58494.1 - 0.46 10.7 7.1 1.3 9.3 0.5 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 AII58494.1 - 1.5 9.0 11.7 0.38 10.9 2.0 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain PAS_9 PF13426.7 AII58495.1 - 3.3e-09 36.9 0.1 1.3e-08 35.1 0.0 1.9 2 0 0 2 2 2 1 PAS domain HisKA_3 PF07730.13 AII58495.1 - 7.5e-08 32.8 0.0 1.6e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase PAS PF00989.25 AII58495.1 - 3e-07 30.4 0.4 9e-06 25.7 0.0 2.6 2 1 1 3 3 3 1 PAS fold HATPase_c PF02518.26 AII58495.1 - 1.7e-06 28.5 3.1 4e-06 27.3 1.2 2.5 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 AII58495.1 - 0.00014 22.1 0.0 0.00027 21.2 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 AII58495.1 - 0.0023 18.2 0.0 0.0065 16.7 0.0 1.8 1 0 0 1 1 1 1 PAS fold HATPase_c_2 PF13581.6 AII58495.1 - 0.029 14.3 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain DUF3445 PF11927.8 AII58495.1 - 0.1 12.2 0.2 0.43 10.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3445) Colicin_immun PF09204.10 AII58495.1 - 0.12 12.9 0.3 0.38 11.3 0.3 1.8 2 0 0 2 2 2 0 Bacterial self-protective colicin-like immunity Response_reg PF00072.24 AII58496.1 - 6.1e-21 74.7 0.1 1.6e-20 73.4 0.0 1.7 2 0 0 2 2 2 1 Response regulator receiver domain GerE PF00196.19 AII58496.1 - 7e-15 54.3 0.3 1.5e-14 53.3 0.3 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_23 PF13384.6 AII58496.1 - 0.0023 17.7 0.0 0.0075 16.0 0.0 1.9 1 1 0 1 1 1 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 AII58496.1 - 0.012 15.3 0.0 0.031 13.9 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 Sigma70_r4 PF04545.16 AII58496.1 - 0.037 13.5 0.0 0.078 12.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 DUF3290 PF11694.8 AII58497.1 - 0.17 11.8 2.6 0.7 9.9 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) DUF2207 PF09972.9 AII58497.1 - 2.1 7.0 6.9 2.3 6.9 6.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RseC_MucC PF04246.12 AII58497.1 - 6.4 6.7 7.0 2.5 8.1 2.5 1.9 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF202 PF02656.15 AII58497.1 - 9.2 6.8 12.4 92 3.6 12.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Dehalogenase PF13486.6 AII58498.1 - 2.9e-68 230.4 0.0 3.9e-68 229.9 0.0 1.2 1 0 0 1 1 1 1 Reductive dehalogenase subunit Fer4_16 PF13484.6 AII58498.1 - 5.9e-08 33.5 9.5 1.8e-07 32.0 9.4 1.9 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4 PF00037.27 AII58498.1 - 0.0011 18.7 11.6 0.0021 17.8 5.2 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain TAT_signal PF10518.9 AII58498.1 - 0.0028 17.4 2.0 0.0028 17.4 2.0 2.6 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence Fer4_7 PF12838.7 AII58498.1 - 0.29 11.8 11.5 0.98 10.1 11.5 2.0 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 AII58498.1 - 0.87 9.8 12.4 0.14 12.3 2.0 2.1 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 AII58498.1 - 3.4 8.2 11.1 27 5.3 11.7 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 AII58498.1 - 9.3 6.9 10.3 30 5.2 10.4 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain MarR_2 PF12802.7 AII58499.1 - 2.5e-06 27.3 0.0 3.8e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AII58499.1 - 0.012 16.0 0.0 0.02 15.3 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain LexA_DNA_bind PF01726.16 AII58499.1 - 0.015 15.1 0.6 0.036 13.8 0.6 1.7 1 1 0 1 1 1 0 LexA DNA binding domain Phage_TAC_3 PF06896.11 AII58499.1 - 0.024 15.2 0.3 0.048 14.2 0.3 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone proteins, TAC HTH_45 PF14947.6 AII58499.1 - 0.051 13.6 0.1 0.25 11.4 0.0 2.1 2 1 0 2 2 2 0 Winged helix-turn-helix MarR PF01047.22 AII58499.1 - 0.061 13.2 0.2 0.13 12.2 0.2 1.6 1 0 0 1 1 1 0 MarR family Phage_TAC_4 PF08748.11 AII58499.1 - 0.069 13.5 0.2 0.12 12.7 0.2 1.5 1 1 0 1 1 1 0 Phage tail assembly chaperone GerE PF00196.19 AII58500.1 - 1.1e-09 37.7 0.2 3.3e-09 36.1 0.2 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family HTH_40 PF14493.6 AII58500.1 - 0.00094 19.6 0.7 0.0039 17.6 0.0 2.2 2 1 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 AII58500.1 - 0.0041 16.8 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 TMPIT PF07851.13 AII58500.1 - 0.06 12.6 0.2 0.1 11.9 0.2 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF4258 PF14076.6 AII58501.1 - 0.088 13.2 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4258) Gln-synt_C PF00120.24 AII58502.1 - 2.5e-54 184.6 0.0 9.8e-54 182.6 0.0 1.8 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 AII58502.1 - 6.6e-12 45.0 0.0 1.2e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain LPD26 PF18842.1 AII58502.1 - 0.19 11.7 0.1 0.55 10.2 0.0 1.8 2 0 0 2 2 2 0 Large polyvalent protein associated domain 26 DUF981 PF06168.11 AII58503.1 - 0.005 16.8 6.0 0.0057 16.6 6.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF981) DUF996 PF06195.13 AII58503.1 - 0.011 16.0 0.2 0.011 16.0 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF996) BofA PF07441.11 AII58503.1 - 0.19 12.0 11.6 0.55 10.5 11.6 1.7 1 1 0 1 1 1 0 SigmaK-factor processing regulatory protein BofA TerC PF03741.16 AII58503.1 - 0.32 10.7 6.0 0.28 10.8 5.3 1.2 1 1 0 1 1 1 0 Integral membrane protein TerC family DUF2892 PF11127.8 AII58503.1 - 0.98 9.5 10.7 0.14 12.2 6.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) DUF1418 PF07214.12 AII58503.1 - 2.7 7.9 8.0 0.39 10.6 3.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1418) Tetraspanin PF00335.20 AII58503.1 - 7.7 6.1 7.6 8.7 6.0 7.6 1.1 1 0 0 1 1 1 0 Tetraspanin family Response_reg PF00072.24 AII58504.1 - 3.5e-28 98.0 0.1 1.3e-27 96.2 0.1 1.7 2 0 0 2 2 2 1 Response regulator receiver domain Trans_reg_C PF00486.28 AII58504.1 - 2.5e-17 62.7 0.0 4.3e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal potato_inhibit PF00280.18 AII58504.1 - 0.07 13.8 0.0 0.28 11.9 0.0 1.9 2 0 0 2 2 2 0 Potato inhibitor I family Rnf-Nqr PF02508.14 AII58505.1 - 0.4 10.6 6.5 0.46 10.5 6.5 1.1 1 0 0 1 1 1 0 Rnf-Nqr subunit, membrane protein DUF202 PF02656.15 AII58505.1 - 0.84 10.1 10.3 1.9 9.0 4.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Dehalogenase PF13486.6 AII58506.1 - 2e-78 263.7 0.0 2.8e-78 263.2 0.0 1.2 1 0 0 1 1 1 1 Reductive dehalogenase subunit Fer4_16 PF13484.6 AII58506.1 - 2.1e-08 34.9 9.3 5.1e-08 33.7 9.3 1.7 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain TAT_signal PF10518.9 AII58506.1 - 6.1e-05 22.7 1.2 6.1e-05 22.7 1.2 1.8 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence Fer4 PF00037.27 AII58506.1 - 0.00011 21.9 8.3 0.00057 19.6 4.6 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_7 PF12838.7 AII58506.1 - 0.0056 17.2 9.1 0.014 16.0 9.1 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AII58506.1 - 0.024 14.8 10.6 0.21 11.8 11.4 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 AII58506.1 - 0.26 11.7 9.6 0.73 10.3 9.7 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_10 PF13237.6 AII58506.1 - 3.1 8.0 15.1 94 3.2 16.7 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 AII58506.1 - 4.8 7.8 10.6 12 6.6 10.6 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain MarR_2 PF12802.7 AII58507.1 - 2.5e-06 27.3 0.0 3.8e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AII58507.1 - 0.012 16.0 0.0 0.02 15.3 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain LexA_DNA_bind PF01726.16 AII58507.1 - 0.015 15.1 0.6 0.036 13.8 0.6 1.7 1 1 0 1 1 1 0 LexA DNA binding domain Phage_TAC_3 PF06896.11 AII58507.1 - 0.024 15.2 0.3 0.048 14.2 0.3 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone proteins, TAC HTH_45 PF14947.6 AII58507.1 - 0.051 13.6 0.1 0.25 11.4 0.0 2.1 2 1 0 2 2 2 0 Winged helix-turn-helix MarR PF01047.22 AII58507.1 - 0.061 13.2 0.2 0.13 12.2 0.2 1.6 1 0 0 1 1 1 0 MarR family Phage_TAC_4 PF08748.11 AII58507.1 - 0.069 13.5 0.2 0.12 12.7 0.2 1.5 1 1 0 1 1 1 0 Phage tail assembly chaperone ABC2_membrane_2 PF12679.7 AII58508.1 - 0.004 16.5 2.7 0.0048 16.2 2.7 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF2976 PF11190.8 AII58508.1 - 0.0074 16.1 6.4 0.02 14.7 2.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2976) Bax1-I PF01027.20 AII58508.1 - 0.0095 15.8 4.5 0.011 15.6 4.5 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF1304 PF06993.12 AII58508.1 - 0.027 14.5 2.6 0.16 12.0 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1304) ABC2_membrane PF01061.24 AII58508.1 - 0.034 13.6 6.8 0.04 13.3 6.8 1.1 1 0 0 1 1 1 0 ABC-2 type transporter VIT1 PF01988.19 AII58508.1 - 0.072 12.9 5.7 0.085 12.7 5.7 1.1 1 0 0 1 1 1 0 VIT family DUF2919 PF11143.8 AII58508.1 - 0.11 12.9 4.6 0.12 12.7 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2919) YwiC PF14256.6 AII58508.1 - 0.11 12.8 6.6 0.17 12.2 6.6 1.4 1 0 0 1 1 1 0 YwiC-like protein DUF2070 PF09843.9 AII58508.1 - 0.16 10.3 0.9 0.17 10.1 0.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4131 PF13567.6 AII58508.1 - 0.18 11.5 6.2 0.05 13.2 3.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) SLATT_1 PF18181.1 AII58508.1 - 0.23 11.4 4.5 0.41 10.6 3.6 1.8 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Glucos_trans_II PF14264.6 AII58508.1 - 0.24 10.7 5.2 0.41 10.0 5.2 1.5 1 1 0 1 1 1 0 Glucosyl transferase GtrII LptF_LptG PF03739.14 AII58508.1 - 0.36 9.6 7.5 0.39 9.5 7.5 1.0 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG DUF1129 PF06570.11 AII58508.1 - 0.45 10.0 6.8 0.62 9.5 6.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) DUF308 PF03729.13 AII58508.1 - 0.49 10.8 11.9 0.36 11.2 7.8 2.0 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) DUF456 PF04306.13 AII58508.1 - 0.57 10.5 11.8 1.6 9.0 11.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF456) PalH PF08733.10 AII58508.1 - 2.3 7.2 6.8 2.6 7.0 6.8 1.0 1 0 0 1 1 1 0 PalH/RIM21 DUF4282 PF14110.6 AII58508.1 - 3.4 8.5 10.6 45 4.9 10.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4282) DUF2561 PF10812.8 AII58508.1 - 7.4 6.5 9.1 1.4 8.9 4.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2561) DUF4064 PF13273.6 AII58508.1 - 7.8 6.8 10.6 3.9e+02 1.4 10.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) DUF983 PF06170.12 AII58508.1 - 9.4 6.7 8.5 13 6.3 3.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF983) Dehalogenase PF13486.6 AII58509.1 - 2.9e-99 332.1 0.1 4e-99 331.6 0.1 1.2 1 0 0 1 1 1 1 Reductive dehalogenase subunit Fer4_16 PF13484.6 AII58509.1 - 9.2e-08 32.9 8.3 2.8e-07 31.3 8.3 1.9 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 AII58509.1 - 2.1e-06 28.2 8.3 6e-06 26.7 8.3 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AII58509.1 - 2e-05 24.6 5.6 0.037 14.2 0.3 2.6 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 AII58509.1 - 5.6e-05 23.6 6.5 0.00013 22.5 6.5 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AII58509.1 - 0.00014 22.0 8.4 0.0004 20.5 8.4 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain TAT_signal PF10518.9 AII58509.1 - 0.00066 19.4 5.6 0.00066 19.4 5.6 2.3 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence Fer4 PF00037.27 AII58509.1 - 0.0014 18.3 2.8 0.0014 18.3 2.8 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_8 PF13183.6 AII58509.1 - 0.0036 17.7 8.2 0.015 15.7 8.3 2.0 1 1 0 1 1 1 1 4Fe-4S dicluster domain WAK_assoc PF14380.6 AII58509.1 - 0.031 15.0 2.1 0.12 13.2 2.1 1.8 2 0 0 2 2 2 0 Wall-associated receptor kinase C-terminal Fer4_21 PF14697.6 AII58509.1 - 0.059 13.5 4.4 4.4 7.5 0.7 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 AII58509.1 - 0.54 10.5 15.5 0.1 12.7 1.7 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 AII58509.1 - 2.8 8.7 14.4 13 6.5 3.7 2.9 2 0 0 2 2 2 0 4Fe-4S binding domain Trans_reg_C PF00486.28 AII58510.1 - 9.5e-10 38.4 0.1 2e-09 37.4 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 AII58510.1 - 0.0029 17.8 0.1 0.0054 16.9 0.1 1.5 1 1 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AII58511.1 - 3.6e-22 78.2 0.0 5.5e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 AII58511.1 - 2.4e-09 37.4 0.0 5.9e-09 36.1 0.0 1.6 2 0 0 2 2 2 1 Response regulator receiver domain MarR_2 PF12802.7 AII58512.1 - 2.8e-07 30.3 0.0 4.3e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AII58512.1 - 9.9e-06 26.0 0.0 1.9e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR PF01047.22 AII58512.1 - 6.8e-05 22.7 0.3 0.00014 21.7 0.0 1.7 2 0 0 2 2 2 1 MarR family TrmB PF01978.19 AII58512.1 - 0.042 13.7 0.0 0.079 12.8 0.0 1.6 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Melittin PF01372.17 AII58513.1 - 0.021 14.7 0.4 0.78 9.8 0.1 2.6 2 0 0 2 2 2 0 Melittin TssN PF17555.2 AII58513.1 - 0.27 10.6 4.8 0.28 10.5 4.8 1.0 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF4231 PF14015.6 AII58513.1 - 0.47 11.0 3.6 0.23 11.9 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) DUF3290 PF11694.8 AII58513.1 - 1.4 8.9 3.0 1.6 8.7 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) DUF202 PF02656.15 AII58513.1 - 1.6 9.2 12.2 0.94 10.0 7.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF805 PF05656.14 AII58513.1 - 4.6 7.7 8.1 25 5.4 8.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF805) Tetraspanin PF00335.20 AII58513.1 - 8.5 6.0 9.6 38 3.9 9.6 1.8 1 1 0 1 1 1 0 Tetraspanin family Dehalogenase PF13486.6 AII58514.1 - 3.2e-66 223.7 0.0 4.7e-66 223.1 0.0 1.3 1 0 0 1 1 1 1 Reductive dehalogenase subunit Fer4_16 PF13484.6 AII58514.1 - 1.2e-07 32.6 10.2 2.6e-07 31.5 10.2 1.6 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4 PF00037.27 AII58514.1 - 1e-05 25.1 9.0 0.00011 21.9 4.9 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain TAT_signal PF10518.9 AII58514.1 - 2.4e-05 24.0 3.5 0.0001 22.0 3.5 2.2 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence Fer4_7 PF12838.7 AII58514.1 - 0.0042 17.6 11.1 0.0092 16.6 11.1 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AII58514.1 - 0.022 14.9 1.2 0.022 14.9 1.2 2.4 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 AII58514.1 - 0.089 13.3 6.9 0.47 11.0 7.5 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_10 PF13237.6 AII58514.1 - 0.36 11.0 13.8 2.1 8.5 14.4 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 AII58514.1 - 6.4 7.0 17.5 1.3 9.2 5.9 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Diphthami_syn_2 PF01902.17 AII58515.1 - 5.9e-44 150.2 0.0 6.7e-44 150.0 0.0 1.0 1 0 0 1 1 1 1 Diphthamide synthase CutC PF03932.14 AII58515.1 - 0.093 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 CutC family CxxCxxCC PF03692.15 AII58516.1 - 4.4e-08 33.7 0.2 1.1e-07 32.5 0.2 1.6 1 1 0 1 1 1 1 Putative zinc- or iron-chelating domain Tim29 PF10171.9 AII58516.1 - 0.079 12.4 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Translocase of the Inner Mitochondrial membrane 29 DUF1965 PF09248.10 AII58516.1 - 0.15 11.9 1.0 0.29 10.9 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) DUF3397 PF11877.8 AII58517.1 - 0.0011 19.1 5.7 0.0021 18.2 5.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3397) DUF368 PF04018.13 AII58517.1 - 0.06 12.9 5.1 0.071 12.7 5.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF368) TMEM100 PF16311.5 AII58517.1 - 0.8 9.3 5.5 0.73 9.4 1.5 2.0 1 1 1 2 2 2 0 Transmembrane protein 100 DUF2085 PF09858.9 AII58517.1 - 1.4 9.4 4.9 2.3 8.8 4.9 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2085) FtsX PF02687.21 AII58517.1 - 1.9 9.0 9.5 4.7 7.7 9.5 1.6 1 1 0 1 1 1 0 FtsX-like permease family Dehalogenase PF13486.6 AII58518.1 - 1.4e-57 195.3 0.0 1.9e-57 194.8 0.0 1.2 1 0 0 1 1 1 1 Reductive dehalogenase subunit Fer4_16 PF13484.6 AII58518.1 - 1.6e-09 38.6 7.5 3e-09 37.7 7.5 1.5 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 AII58518.1 - 6.2e-09 36.3 9.0 1.2e-08 35.4 9.0 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AII58518.1 - 3.7e-06 26.9 5.0 0.03 14.4 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 AII58518.1 - 1.8e-05 25.2 6.1 3.8e-05 24.1 6.1 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 AII58518.1 - 2e-05 24.2 13.2 0.0001 21.9 4.2 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain TAT_signal PF10518.9 AII58518.1 - 3e-05 23.7 4.0 3e-05 23.7 4.0 2.3 2 0 0 2 2 1 1 TAT (twin-arginine translocation) pathway signal sequence Fer4_9 PF13187.6 AII58518.1 - 0.0018 18.4 11.6 0.046 13.9 12.3 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.7 AII58518.1 - 0.0066 16.5 13.2 0.016 15.2 1.6 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_8 PF13183.6 AII58518.1 - 0.0073 16.7 7.7 0.02 15.3 7.8 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 AII58518.1 - 0.018 15.2 5.0 0.39 10.9 0.9 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 AII58518.1 - 0.034 14.7 14.2 0.34 11.5 2.7 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.7 AII58518.1 - 0.83 9.8 14.3 0.056 13.5 4.3 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain MarR_2 PF12802.7 AII58519.1 - 2.8e-05 23.9 0.1 0.00013 21.8 0.0 2.1 3 0 0 3 3 3 1 MarR family MarR PF01047.22 AII58519.1 - 0.00045 20.1 0.1 0.0017 18.3 0.1 2.0 1 1 1 2 2 2 1 MarR family TrmB PF01978.19 AII58519.1 - 0.0099 15.7 0.3 4.3 7.3 0.0 2.5 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB Crp PF00325.20 AII58519.1 - 0.047 13.3 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family PAX PF00292.18 AII58519.1 - 0.051 13.5 0.1 0.75 9.7 0.1 2.1 1 1 1 2 2 2 0 'Paired box' domain CxxCxxCC PF03692.15 AII58521.1 - 3.9e-05 24.2 9.8 0.00012 22.7 9.8 1.7 1 1 0 1 1 1 1 Putative zinc- or iron-chelating domain DUF3290 PF11694.8 AII58522.1 - 0.04 13.9 0.5 2.1 8.3 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3290) DUF4231 PF14015.6 AII58522.1 - 0.21 12.1 3.6 5.3 7.6 3.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) DUF308 PF03729.13 AII58522.1 - 0.24 11.7 12.6 0.96 9.8 11.6 2.1 1 1 0 1 1 1 0 Short repeat of unknown function (DUF308) Trp_oprn_chp PF09534.10 AII58522.1 - 1 9.1 7.4 0.14 11.9 2.1 1.8 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4131 PF13567.6 AII58522.1 - 4.4 6.9 11.5 38 3.9 11.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Dehalogenase PF13486.6 AII58523.1 - 8.9e-96 320.6 0.0 1.2e-95 320.2 0.0 1.2 1 0 0 1 1 1 1 Reductive dehalogenase subunit Fer4_16 PF13484.6 AII58523.1 - 4.1e-07 30.8 8.9 9.5e-07 29.7 8.9 1.7 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 AII58523.1 - 3.2e-06 27.6 9.7 6.7e-06 26.6 9.7 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 AII58523.1 - 5.6e-05 22.8 4.6 5.6e-05 22.8 4.6 2.7 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_10 PF13237.6 AII58523.1 - 0.00028 20.9 7.0 0.11 12.6 0.6 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AII58523.1 - 0.0006 20.2 2.8 0.61 10.6 0.1 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 AII58523.1 - 0.00073 19.6 9.2 0.0016 18.5 9.2 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 AII58523.1 - 0.0045 17.5 8.1 0.012 16.1 8.1 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 AII58523.1 - 0.021 14.9 13.5 0.037 14.1 1.9 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.7 AII58523.1 - 0.13 12.4 14.2 0.043 13.9 3.9 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain TAT_signal PF10518.9 AII58523.1 - 0.13 12.2 3.1 0.38 10.7 3.1 1.8 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Fer4_21 PF14697.6 AII58523.1 - 2.4 8.3 9.7 2.2 8.5 1.0 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_20 PF14691.6 AII58523.1 - 4 7.2 6.6 0.43 10.4 0.7 2.1 2 0 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Response_reg PF00072.24 AII58524.1 - 1.7e-23 82.9 0.4 2.8e-23 82.2 0.4 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AII58524.1 - 1.2e-13 50.9 0.0 3.4e-13 49.5 0.0 1.7 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal HATPase_c PF02518.26 AII58525.1 - 1.7e-27 96.1 0.0 3.3e-27 95.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 AII58525.1 - 2.4e-20 72.7 0.0 4.2e-09 36.6 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 AII58525.1 - 2.5e-11 43.6 0.0 0.00013 22.0 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 AII58525.1 - 4.5e-11 42.5 0.0 0.0001 22.2 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 AII58525.1 - 1.3e-07 31.9 0.0 0.0068 16.7 0.0 2.7 2 1 0 2 2 2 2 PAS fold HisKA PF00512.25 AII58525.1 - 4.8e-06 26.5 0.0 1.7e-05 24.8 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 AII58525.1 - 0.00043 20.1 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 AII58525.1 - 0.00091 19.5 0.0 0.018 15.3 0.0 3.0 3 0 0 3 3 3 1 PAS fold PspA_IM30 PF04012.12 AII58525.1 - 0.012 15.2 2.0 0.026 14.1 0.1 2.0 2 0 0 2 2 2 0 PspA/IM30 family RICH PF05062.12 AII58525.1 - 0.029 14.7 1.2 0.088 13.2 1.2 1.8 1 0 0 1 1 1 0 RICH domain DUF4618 PF15397.6 AII58525.1 - 0.071 12.5 5.9 0.53 9.7 1.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) CREPT PF16566.5 AII58525.1 - 0.62 10.2 4.2 0.82 9.8 0.5 2.2 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour PAS_9 PF13426.7 AII58526.1 - 4.9e-41 139.2 0.3 4.4e-14 52.6 0.0 4.7 4 0 0 4 4 4 4 PAS domain PAS PF00989.25 AII58526.1 - 6.8e-37 125.9 0.0 3.1e-08 33.6 0.0 4.8 4 0 0 4 4 4 4 PAS fold PAS_4 PF08448.10 AII58526.1 - 5.4e-34 116.8 0.0 8e-10 39.0 0.0 4.3 4 0 0 4 4 4 4 PAS fold Response_reg PF00072.24 AII58526.1 - 8.3e-25 87.1 0.1 2.6e-24 85.6 0.1 1.9 1 0 0 1 1 1 1 Response regulator receiver domain PAS_3 PF08447.12 AII58526.1 - 1.6e-24 86.0 0.1 4.3e-09 36.5 0.1 4.6 4 0 0 4 4 4 4 PAS fold HATPase_c PF02518.26 AII58526.1 - 4.2e-22 78.8 0.0 9.7e-22 77.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 5TM-5TMR_LYT PF07694.12 AII58526.1 - 4.1e-21 75.2 23.1 6e-21 74.7 23.1 1.2 1 0 0 1 1 1 1 5TMR of 5TMR-LYT PAS_8 PF13188.7 AII58526.1 - 2.4e-19 68.9 0.0 9.4e-07 28.7 0.0 3.9 3 0 0 3 3 3 3 PAS domain HisKA PF00512.25 AII58526.1 - 2.3e-18 66.0 1.1 1.2e-17 63.7 0.0 2.7 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 AII58526.1 - 0.0047 16.8 0.0 0.015 15.1 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AII58526.1 - 0.0057 16.5 0.0 0.017 15.0 0.0 1.9 1 0 0 1 1 1 1 GHKL domain HATPase_c_2 PF13581.6 AII58526.1 - 0.035 14.1 0.0 0.089 12.7 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain PEP-utilisers_N PF05524.13 AII58526.1 - 0.051 13.7 5.1 9.3 6.5 0.1 4.6 5 0 0 5 5 5 0 PEP-utilising enzyme, N-terminal Nitro_FeMo-Co PF02579.17 AII58527.1 - 6.9e-17 61.6 1.5 4.2e-16 59.1 1.5 1.9 1 1 0 1 1 1 1 Dinitrogenase iron-molybdenum cofactor DUF4149 PF13664.6 AII58528.1 - 0.082 13.2 2.6 0.33 11.3 2.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4149) Phage_holin_3_6 PF07332.11 AII58528.1 - 0.084 12.9 6.9 0.46 10.5 6.9 1.9 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4436 PF14494.6 AII58528.1 - 0.097 11.9 0.0 0.12 11.6 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4436) YwiC PF14256.6 AII58528.1 - 0.14 12.5 4.8 0.18 12.1 4.8 1.1 1 0 0 1 1 1 0 YwiC-like protein Bax1-I PF01027.20 AII58528.1 - 0.17 11.7 3.7 0.1 12.4 0.6 1.5 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF4131 PF13567.6 AII58528.1 - 0.37 10.4 7.4 0.098 12.3 2.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF3180 PF11377.8 AII58528.1 - 0.78 9.9 7.1 0.34 11.0 2.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3180) DUF4203 PF13886.6 AII58528.1 - 1 9.0 9.7 1.3 8.6 2.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4203) DUF202 PF02656.15 AII58528.1 - 1.1 9.7 7.3 5.5 7.5 7.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Dehalogenase PF13486.6 AII58529.1 - 1.1e-94 317.1 0.1 1.5e-94 316.7 0.1 1.1 1 0 0 1 1 1 1 Reductive dehalogenase subunit Fer4_16 PF13484.6 AII58529.1 - 5.3e-07 30.5 6.9 1e-06 29.6 6.9 1.5 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 AII58529.1 - 3.6e-06 27.0 3.3 0.03 14.4 0.2 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 AII58529.1 - 6.1e-06 26.7 7.8 1.1e-05 25.9 7.8 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 AII58529.1 - 0.0011 18.7 2.4 0.0011 18.7 2.4 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_17 PF13534.6 AII58529.1 - 0.0012 19.4 5.5 0.0028 18.2 5.5 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain TAT_signal PF10518.9 AII58529.1 - 0.0013 18.5 4.9 0.0013 18.5 4.9 2.1 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence Fer4_9 PF13187.6 AII58529.1 - 0.0015 18.6 6.9 0.011 15.9 8.0 1.8 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 AII58529.1 - 0.033 14.3 1.1 0.033 14.3 1.1 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain UCR_Fe-S_N PF10399.9 AII58529.1 - 0.074 12.4 0.6 0.18 11.2 0.6 1.6 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Fer4_8 PF13183.6 AII58529.1 - 0.11 13.0 9.0 0.88 10.1 9.8 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 AII58529.1 - 0.54 10.4 6.8 1.3 9.3 0.5 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 AII58529.1 - 0.63 10.7 15.5 4.7 8.0 3.7 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain MarR_2 PF12802.7 AII58530.1 - 7.9e-07 28.9 0.0 1.4e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AII58530.1 - 0.00062 20.2 0.2 0.0016 18.9 0.1 1.7 2 0 0 2 2 2 1 Winged helix DNA-binding domain MarR PF01047.22 AII58530.1 - 0.0039 17.1 0.2 0.011 15.6 0.0 1.9 2 0 0 2 2 2 1 MarR family HTH_34 PF13601.6 AII58530.1 - 0.088 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain Fe_dep_repress PF01325.19 AII58530.1 - 0.094 12.9 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain DUF1418 PF07214.12 AII58531.1 - 0.0039 17.0 0.6 0.0072 16.2 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1418) AA_permease_2 PF13520.6 AII58531.1 - 0.0054 15.6 2.8 0.0064 15.4 2.8 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3290 PF11694.8 AII58531.1 - 0.06 13.3 1.1 0.062 13.3 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3290) Caa3_CtaG PF09678.10 AII58531.1 - 0.16 11.4 7.2 0.094 12.2 5.1 1.6 1 1 1 2 2 2 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) DUF2892 PF11127.8 AII58531.1 - 0.27 11.3 8.4 0.43 10.7 3.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) ABC2_membrane_5 PF13346.6 AII58531.1 - 0.75 9.3 6.1 4.8 6.7 6.1 1.9 1 1 0 1 1 1 0 ABC-2 family transporter protein MNHE PF01899.16 AII58531.1 - 1.3 8.8 5.8 1 9.1 4.7 1.3 1 1 0 1 1 1 0 Na+/H+ ion antiporter subunit DUF202 PF02656.15 AII58531.1 - 1.5 9.4 8.4 0.52 10.8 3.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Tetraspanin PF00335.20 AII58531.1 - 2.3 7.9 5.1 3.3 7.3 5.1 1.3 1 0 0 1 1 1 0 Tetraspanin family DUF4131 PF13567.6 AII58531.1 - 2.4 7.8 11.9 0.13 12.0 3.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF4064 PF13273.6 AII58531.1 - 4.3 7.7 8.9 24 5.2 8.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) Dehalogenase PF13486.6 AII58532.1 - 2.7e-74 250.2 0.1 4.2e-74 249.5 0.1 1.3 1 0 0 1 1 1 1 Reductive dehalogenase subunit Fer4_16 PF13484.6 AII58532.1 - 8.3e-11 42.7 6.1 1.6e-10 41.7 6.1 1.5 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 AII58532.1 - 0.00015 22.3 6.3 0.0003 21.3 6.3 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 AII58532.1 - 0.0012 19.2 0.4 0.55 10.7 0.1 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain TAT_signal PF10518.9 AII58532.1 - 0.0017 18.1 4.0 0.0017 18.1 4.0 2.5 3 0 0 3 3 3 1 TAT (twin-arginine translocation) pathway signal sequence Fer4_17 PF13534.6 AII58532.1 - 0.013 16.0 2.2 0.37 11.4 0.5 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4 PF00037.27 AII58532.1 - 0.015 15.1 7.5 0.019 14.8 0.7 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_10 PF13237.6 AII58532.1 - 0.15 12.2 11.2 2.8 8.1 12.0 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 AII58532.1 - 0.9 10.2 5.6 4.1 8.1 0.6 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_9 PF13187.6 AII58532.1 - 2 8.7 12.2 0.36 11.0 2.9 2.4 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 AII58532.1 - 3.4 7.9 7.6 1.5 9.0 2.0 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 AII58532.1 - 7.6 7.7 13.7 1.2 10.2 4.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain DUF4389 PF14333.6 AII58533.1 - 3.9e-22 78.0 18.0 2.1e-15 56.4 5.0 3.1 2 1 1 3 3 3 3 Domain of unknown function (DUF4389) Peptidase_M73 PF12389.8 AII58533.1 - 0.088 12.6 0.1 0.088 12.6 0.1 1.4 2 0 0 2 2 2 0 Camelysin metallo-endopeptidase Fer4_16 PF13484.6 AII58534.1 - 3.2e-08 34.4 8.5 6e-08 33.5 8.5 1.5 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_6 PF12837.7 AII58534.1 - 0.00053 20.0 12.0 0.083 13.0 0.4 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 AII58534.1 - 0.0033 17.9 9.3 0.72 10.4 7.3 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 AII58534.1 - 0.0052 16.9 13.6 0.11 12.6 0.2 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AII58534.1 - 0.024 15.1 15.6 0.036 14.5 13.9 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 AII58534.1 - 0.033 14.8 14.0 0.26 11.9 14.1 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4 PF00037.27 AII58534.1 - 0.045 13.6 10.9 0.086 12.7 0.5 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_2 PF12797.7 AII58534.1 - 0.074 13.2 12.4 0.62 10.3 1.7 2.9 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 AII58534.1 - 0.09 13.3 9.5 0.84 10.3 0.2 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_9 PF13187.6 AII58534.1 - 0.13 12.5 17.9 0.96 9.7 15.4 2.4 1 1 2 3 3 3 0 4Fe-4S dicluster domain Dehalogenase PF13486.6 AII58534.1 - 0.15 11.4 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Reductive dehalogenase subunit Fer4_21 PF14697.6 AII58534.1 - 0.31 11.2 11.9 0.51 10.5 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain PAS_9 PF13426.7 AII58535.1 - 9.4e-82 270.0 7.0 2.6e-12 46.9 0.0 8.3 8 0 0 8 8 8 8 PAS domain PAS PF00989.25 AII58535.1 - 4.3e-69 229.7 0.1 4.7e-13 49.1 0.0 8.4 8 0 0 8 8 8 8 PAS fold PAS_4 PF08448.10 AII58535.1 - 9e-66 219.0 0.0 1.1e-13 51.4 0.0 8.5 8 0 0 8 8 8 8 PAS fold PAS_8 PF13188.7 AII58535.1 - 3.5e-48 160.9 0.0 7.8e-09 35.4 0.0 7.7 7 0 0 7 7 7 7 PAS domain PAS_3 PF08447.12 AII58535.1 - 7.5e-39 131.9 0.0 9.5e-08 32.2 0.0 8.2 8 0 0 8 8 8 5 PAS fold Response_reg PF00072.24 AII58535.1 - 1.2e-24 86.6 0.1 4.2e-23 81.7 0.0 2.6 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 AII58535.1 - 2e-20 73.4 0.1 5.6e-19 68.7 0.0 2.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AII58535.1 - 2e-15 56.5 0.0 8.3e-15 54.6 0.0 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_12 PF18095.1 AII58535.1 - 4.5e-08 32.9 0.3 0.0058 16.3 0.0 3.3 4 0 0 4 4 4 2 UPF0242 C-terminal PAS-like domain PAS_7 PF12860.7 AII58535.1 - 4.4e-06 26.8 4.7 1.7 8.8 0.0 7.7 7 2 0 7 7 7 1 PAS fold PAS_10 PF13596.6 AII58535.1 - 0.0012 19.4 0.3 0.04 14.5 0.0 3.7 4 0 0 4 4 4 1 PAS domain HATPase_c_3 PF13589.6 AII58535.1 - 0.0048 16.7 0.2 0.39 10.5 0.0 3.4 3 1 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_11 PF14598.6 AII58535.1 - 0.018 15.2 0.0 0.23 11.6 0.0 3.0 3 0 0 3 3 3 0 PAS domain HATPase_c_5 PF14501.6 AII58535.1 - 0.03 14.2 0.0 0.46 10.4 0.0 2.8 3 0 0 3 3 3 0 GHKL domain Response_reg PF00072.24 AII58536.1 - 2.5e-27 95.3 1.9 2.5e-26 92.0 0.8 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HD PF01966.22 AII58536.1 - 6.7e-20 71.5 0.0 1.3e-19 70.6 0.0 1.5 1 0 0 1 1 1 1 HD domain HD_5 PF13487.6 AII58536.1 - 7e-19 67.8 0.1 2e-18 66.4 0.1 1.8 1 0 0 1 1 1 1 HD domain HU-CCDC81_bac_2 PF18175.1 AII58536.1 - 0.072 13.0 0.1 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 2 HDOD PF08668.12 AII58536.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 HDOD domain MPLKIP PF15502.6 AII58537.1 - 0.055 13.7 0.0 0.076 13.2 0.0 1.2 1 0 0 1 1 1 0 M-phase-specific PLK1-interacting protein NPCBM_assoc PF10633.9 AII58538.1 - 2.3e-11 43.8 0.0 3.1e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 NPCBM-associated, NEW3 domain of alpha-galactosidase DUF3153 PF11353.8 AII58538.1 - 0.057 13.0 0.1 0.094 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) DUF916 PF06030.12 AII58538.1 - 0.16 12.1 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) UPF0114 PF03350.16 AII58539.1 - 5.8e-24 84.6 12.7 5.8e-24 84.6 12.7 1.3 2 0 0 2 2 2 1 Uncharacterized protein family, UPF0114 Gpr1_Fun34_YaaH PF01184.19 AII58540.1 - 2.7e-40 138.2 18.4 3e-40 138.1 18.4 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DOMON PF03351.17 AII58541.1 - 4.1e-18 65.8 0.1 7e-18 65.0 0.1 1.3 1 0 0 1 1 1 1 DOMON domain Bact_lectin PF18483.1 AII58541.1 - 0.0093 16.0 0.4 0.02 14.9 0.5 1.7 1 1 0 1 1 1 1 Bacterial lectin ABC_membrane PF00664.23 AII58542.1 - 9.3e-48 163.2 10.6 1.3e-47 162.8 10.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 AII58542.1 - 1.5e-35 122.7 0.0 2.9e-35 121.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 AII58542.1 - 3.9e-05 23.2 0.0 0.0011 18.4 0.0 2.2 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 AII58542.1 - 0.002 17.9 0.0 0.012 15.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 AII58542.1 - 0.0025 18.2 0.1 0.0078 16.6 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain DEAD PF00270.29 AII58542.1 - 0.0025 17.6 0.0 0.0055 16.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 AII58542.1 - 0.0028 18.0 0.0 0.012 15.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 AII58542.1 - 0.012 16.0 0.1 3.2 8.2 0.0 2.7 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 AII58542.1 - 0.014 15.6 0.1 0.18 12.1 0.1 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 AII58542.1 - 0.029 14.3 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 AII58542.1 - 0.043 13.6 0.1 1.5 8.5 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.6 AII58542.1 - 0.083 12.5 0.0 0.27 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 AII58542.1 - 0.13 12.0 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 AII58542.1 - 0.19 12.2 0.0 0.37 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 AII58542.1 - 0.21 11.7 0.4 0.5 10.5 0.4 1.8 1 1 0 1 1 1 0 AAA domain CitMHS PF03600.16 AII58542.1 - 0.22 10.7 9.0 0.51 9.5 9.0 1.6 1 1 0 1 1 1 0 Citrate transporter DUF3149 PF11346.8 AII58542.1 - 0.55 9.9 5.8 1.4 8.6 5.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) TarH PF02203.15 AII58542.1 - 1.1 9.1 6.0 6.5 6.7 6.0 2.3 1 1 0 1 1 1 0 Tar ligand binding domain homologue Radical_SAM_N PF08497.10 AII58543.1 - 5.3e-120 400.2 0.0 7.7e-120 399.6 0.0 1.2 1 0 0 1 1 1 1 Radical SAM N-terminal Radical_SAM PF04055.21 AII58543.1 - 2.2e-14 54.2 0.0 4.9e-14 53.0 0.1 1.6 2 0 0 2 2 2 1 Radical SAM superfamily DUF3362 PF11842.8 AII58543.1 - 2.5e-05 24.6 0.1 5.4e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3362) STE PF02200.16 AII58543.1 - 0.072 13.5 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 STE like transcription factor DUF3913 PF13052.6 AII58543.1 - 0.18 12.1 0.1 0.36 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3913) ACR_tran PF00873.19 AII58544.1 - 3.1e-171 571.4 54.4 8.4e-145 483.9 47.5 2.1 1 1 1 2 2 2 2 AcrB/AcrD/AcrF family MMPL PF03176.15 AII58544.1 - 7.6e-08 31.6 61.1 1e-05 24.6 30.3 2.8 3 0 0 3 3 3 2 MMPL family SecD_SecF PF02355.16 AII58544.1 - 1.8e-06 27.5 43.9 0.0012 18.3 14.0 2.9 2 0 0 2 2 2 2 Protein export membrane protein MarR_2 PF12802.7 AII58545.1 - 2.4e-11 43.3 0.0 3.7e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 MarR family MarR PF01047.22 AII58545.1 - 1.6e-09 37.5 0.0 2.7e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AII58545.1 - 2.4e-07 31.1 0.0 4.4e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_24 PF13412.6 AII58545.1 - 0.00044 19.7 0.0 0.00087 18.8 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 AII58545.1 - 0.0026 17.5 0.0 0.0053 16.5 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain Fe_dep_repress PF01325.19 AII58545.1 - 0.006 16.8 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain TrmB PF01978.19 AII58545.1 - 0.0093 15.8 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB TFIIE_alpha PF02002.17 AII58545.1 - 0.03 14.2 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 TFIIE alpha subunit RuvB_C PF05491.13 AII58545.1 - 0.038 13.9 0.2 0.14 12.0 0.1 2.0 2 1 1 3 3 3 0 RuvB C-terminal winged helix domain HTH_34 PF13601.6 AII58545.1 - 0.046 13.9 0.0 0.075 13.2 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain K-box PF01486.17 AII58545.1 - 0.049 13.8 0.8 0.085 13.0 0.8 1.4 1 0 0 1 1 1 0 K-box region DUF998 PF06197.13 AII58546.1 - 0.0097 15.5 9.0 0.014 15.0 9.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF998) AA_permease_2 PF13520.6 AII58546.1 - 0.051 12.4 5.4 0.058 12.2 5.2 1.3 1 1 0 1 1 1 0 Amino acid permease EamA PF00892.20 AII58546.1 - 0.055 13.6 10.7 0.063 13.5 10.7 1.1 1 0 0 1 1 1 0 EamA-like transporter family DMT_YdcZ PF04657.13 AII58546.1 - 0.95 9.7 10.9 1.9 8.7 10.9 1.5 1 1 0 1 1 1 0 Putative inner membrane exporter, YdcZ Ost5 PF05251.12 AII58546.1 - 1.3 9.3 7.9 0.27 11.5 1.1 2.1 1 1 1 2 2 2 0 Oligosaccharyltransferase subunit 5 YfhO PF09586.10 AII58546.1 - 1.7 6.8 6.4 1.8 6.7 6.4 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Glucos_trans_II PF14264.6 AII58546.1 - 2.4 7.4 10.3 2.4 7.4 8.9 1.6 1 1 1 2 2 2 0 Glucosyl transferase GtrII DUF4131 PF13567.6 AII58546.1 - 4.6 6.9 16.6 0.44 10.2 6.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Tetraspanin PF00335.20 AII58546.1 - 8.4 6.0 7.8 13 5.4 7.8 1.4 1 0 0 1 1 1 0 Tetraspanin family Dehalogenase PF13486.6 AII58547.1 - 1.9e-72 244.1 0.0 3e-72 243.5 0.0 1.3 1 0 0 1 1 1 1 Reductive dehalogenase subunit Fer4_16 PF13484.6 AII58547.1 - 5.4e-10 40.1 10.4 9.8e-10 39.2 10.4 1.5 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain TAT_signal PF10518.9 AII58547.1 - 0.00044 20.0 1.8 0.00044 20.0 1.8 2.5 4 0 0 4 4 4 1 TAT (twin-arginine translocation) pathway signal sequence Fer4_8 PF13183.6 AII58547.1 - 0.0025 18.2 2.6 0.87 10.1 1.3 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 AII58547.1 - 0.018 15.6 4.1 1.3 9.7 2.1 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 AII58547.1 - 0.22 12.1 12.7 0.54 10.9 12.7 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4 PF00037.27 AII58547.1 - 1.6 8.7 14.2 1.3 9.0 4.2 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_9 PF13187.6 AII58547.1 - 5 7.4 16.1 6.9 6.9 7.3 2.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain MarR_2 PF12802.7 AII58548.1 - 4.7e-08 32.8 0.0 7.6e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AII58548.1 - 0.00022 21.7 0.1 0.00044 20.7 0.1 1.6 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR PF01047.22 AII58548.1 - 0.00057 19.8 0.1 0.0011 18.9 0.1 1.5 1 0 0 1 1 1 1 MarR family PIN_8 PF18476.1 AII58548.1 - 0.0073 16.2 0.5 0.011 15.7 0.5 1.2 1 0 0 1 1 1 1 PIN like domain HTH_24 PF13412.6 AII58548.1 - 0.0093 15.5 0.3 0.024 14.2 0.3 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Penicillinase_R PF03965.16 AII58548.1 - 0.022 15.1 0.1 0.043 14.2 0.1 1.6 1 1 0 1 1 1 0 Penicillinase repressor HTH_34 PF13601.6 AII58548.1 - 0.052 13.7 0.0 0.094 12.9 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain LexA_DNA_bind PF01726.16 AII58548.1 - 0.069 12.9 0.1 0.4 10.5 0.1 2.2 1 1 0 1 1 1 0 LexA DNA binding domain TrmB PF01978.19 AII58548.1 - 0.07 13.0 0.4 3.5 7.6 0.0 2.3 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_12 PF08461.10 AII58548.1 - 0.12 12.4 2.6 0.13 12.3 0.7 2.1 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain B12-binding PF02310.19 AII58549.1 - 2.5e-11 43.7 0.0 8.2e-10 38.8 0.0 2.9 3 0 0 3 3 3 1 B12 binding domain PqqD PF05402.12 AII58549.1 - 9.9e-11 41.8 0.1 3.3e-09 36.9 0.0 2.6 2 0 0 2 2 2 1 Coenzyme PQQ synthesis protein D (PqqD) Radical_SAM PF04055.21 AII58549.1 - 3.6e-09 37.2 0.1 1.1e-08 35.7 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily MFS_1 PF07690.16 AII58550.1 - 1.6e-54 185.2 60.3 1.9e-53 181.6 58.6 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 AII58550.1 - 6.9e-13 47.9 26.6 8.8e-13 47.5 26.6 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 AII58550.1 - 4.2e-10 39.1 12.1 4.2e-10 39.1 12.1 3.3 2 1 1 4 4 4 2 Sugar (and other) transporter MFS_2 PF13347.6 AII58550.1 - 8.8e-07 27.8 43.9 0.00014 20.5 4.9 4.1 4 0 0 4 4 4 3 MFS/sugar transport protein MFS_1_like PF12832.7 AII58550.1 - 0.00031 19.7 34.1 0.0037 16.2 8.8 3.2 4 0 0 4 4 4 2 MFS_1 like family MarR PF01047.22 AII58551.1 - 5.5e-14 51.8 0.0 1.3e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 AII58551.1 - 2.9e-12 46.3 0.1 6e-12 45.3 0.1 1.5 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AII58551.1 - 1.5e-07 31.8 0.3 3.7e-07 30.6 0.1 1.7 1 1 1 2 2 2 1 Winged helix DNA-binding domain HTH_24 PF13412.6 AII58551.1 - 5.6e-07 29.0 0.0 1.2e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 AII58551.1 - 5.1e-05 23.0 0.1 0.00013 21.7 0.0 1.6 2 0 0 2 2 2 1 IclR helix-turn-helix domain RPA_C PF08784.11 AII58551.1 - 0.00064 20.3 0.1 0.0011 19.6 0.1 1.4 1 0 0 1 1 1 1 Replication protein A C terminal Fe_dep_repress PF01325.19 AII58551.1 - 0.00078 19.6 0.0 0.0022 18.2 0.0 1.8 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Rrf2 PF02082.20 AII58551.1 - 0.00088 19.6 0.3 0.0044 17.3 0.0 2.2 2 2 0 2 2 2 1 Transcriptional regulator HTH_Crp_2 PF13545.6 AII58551.1 - 0.0036 17.2 0.1 0.0088 16.0 0.1 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain FeoC PF09012.10 AII58551.1 - 0.0073 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 FeoC like transcriptional regulator HTH_20 PF12840.7 AII58551.1 - 0.011 15.8 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain B-block_TFIIIC PF04182.12 AII58551.1 - 0.013 15.7 0.0 0.02 15.0 0.0 1.5 1 1 0 1 1 1 0 B-block binding subunit of TFIIIC Penicillinase_R PF03965.16 AII58551.1 - 0.031 14.6 0.1 0.053 13.9 0.1 1.6 1 1 0 1 1 1 0 Penicillinase repressor HTH_5 PF01022.20 AII58551.1 - 0.04 13.8 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family TrmB PF01978.19 AII58551.1 - 0.052 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF2250 PF10007.9 AII58551.1 - 0.14 12.3 0.1 0.31 11.2 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) Bax1-I PF01027.20 AII58552.1 - 0.0031 17.4 4.0 0.0033 17.3 4.0 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 YhfC PF10086.9 AII58552.1 - 0.013 14.9 2.3 0.016 14.6 2.3 1.1 1 0 0 1 1 1 0 YhfC intramembrane metalloprotease DUF3290 PF11694.8 AII58552.1 - 0.077 13.0 1.8 0.14 12.1 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3290) DUF998 PF06197.13 AII58552.1 - 0.089 12.4 8.8 3.6 7.1 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF998) LptF_LptG PF03739.14 AII58552.1 - 0.31 9.8 6.8 0.36 9.6 6.8 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Colicin_V PF02674.16 AII58552.1 - 0.32 11.0 9.4 0.047 13.7 1.7 2.0 1 1 1 2 2 2 0 Colicin V production protein Phage_holin_3_6 PF07332.11 AII58552.1 - 0.52 10.4 12.6 10 6.2 12.6 2.0 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III COX4_pro PF03626.14 AII58552.1 - 0.72 10.3 9.4 3.1 8.3 9.4 1.9 1 1 0 1 1 1 0 Prokaryotic Cytochrome C oxidase subunit IV PAP2_C PF14360.6 AII58552.1 - 0.79 10.3 5.4 3 8.4 4.0 2.0 1 1 1 2 2 2 0 PAP2 superfamily C-terminal DUF202 PF02656.15 AII58552.1 - 0.93 10.0 9.3 0.2 12.1 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF2070 PF09843.9 AII58552.1 - 1.6 6.9 5.1 0.57 8.4 0.4 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF1418 PF07214.12 AII58552.1 - 4.5 7.2 5.8 7.8 6.4 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1418) DUF4436 PF14494.6 AII58552.1 - 4.5 6.5 7.0 0.76 9.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4436) DUF4131 PF13567.6 AII58552.1 - 5 6.7 10.0 45 3.6 10.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) CcmD PF04995.14 AII58552.1 - 8.2 6.6 11.7 2.1 8.5 0.2 2.7 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) Dehalogenase PF13486.6 AII58553.1 - 1.1e-92 310.5 0.0 1.5e-92 310.1 0.0 1.1 1 0 0 1 1 1 1 Reductive dehalogenase subunit Fer4_16 PF13484.6 AII58553.1 - 1e-07 32.8 8.7 1.8e-07 32.0 8.7 1.5 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 AII58553.1 - 5e-06 27.0 8.0 9.6e-06 26.1 8.0 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AII58553.1 - 1.3e-05 25.2 5.0 0.04 14.0 0.6 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 AII58553.1 - 7.8e-05 23.1 6.0 0.00014 22.4 6.0 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain TAT_signal PF10518.9 AII58553.1 - 9.4e-05 22.1 1.6 9.4e-05 22.1 1.6 1.9 2 0 0 2 2 1 1 TAT (twin-arginine translocation) pathway signal sequence Fer4_9 PF13187.6 AII58553.1 - 0.00043 20.4 8.3 0.00083 19.5 8.3 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 AII58553.1 - 0.0026 17.5 1.4 0.0026 17.5 1.4 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_8 PF13183.6 AII58553.1 - 0.014 15.8 8.7 0.064 13.7 9.1 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_20 PF14691.6 AII58553.1 - 0.055 13.2 0.1 0.055 13.2 0.1 1.9 2 0 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster DUF4431 PF14485.6 AII58553.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) Fer4_21 PF14697.6 AII58553.1 - 0.28 11.4 6.4 4.5 7.5 1.0 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 AII58553.1 - 0.31 11.2 14.4 0.16 12.1 1.1 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 AII58553.1 - 1.7 9.3 14.1 1.9 9.2 2.3 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain MarR_2 PF12802.7 AII58554.1 - 2.6e-07 30.4 0.0 4.1e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 MarR family MarR PF01047.22 AII58554.1 - 8e-06 25.7 0.1 1.3e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 MarR family Fe_dep_repress PF01325.19 AII58554.1 - 0.00086 19.5 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_27 PF13463.6 AII58554.1 - 0.0038 17.7 0.1 0.0068 16.9 0.1 1.5 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_Crp_2 PF13545.6 AII58554.1 - 0.021 14.8 0.0 0.042 13.8 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain TFIIE_alpha PF02002.17 AII58554.1 - 0.045 13.6 0.0 3.1 7.7 0.0 2.3 1 1 1 2 2 2 0 TFIIE alpha subunit TrmB PF01978.19 AII58554.1 - 0.15 11.9 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB AA_permease_2 PF13520.6 AII58555.1 - 0.0066 15.3 5.0 0.0078 15.1 5.0 1.2 1 0 0 1 1 1 1 Amino acid permease Exosortase_EpsH PF09721.10 AII58555.1 - 0.13 11.8 10.6 0.15 11.6 10.6 1.0 1 0 0 1 1 1 0 Transmembrane exosortase (Exosortase_EpsH) ABC2_membrane_5 PF13346.6 AII58555.1 - 0.2 11.2 6.3 0.61 9.6 6.5 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein FUSC_2 PF13515.6 AII58555.1 - 0.42 10.7 8.5 0.61 10.2 8.5 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein-like E1-E2_ATPase PF00122.20 AII58555.1 - 0.83 9.1 3.7 0.34 10.4 0.9 1.6 1 1 1 2 2 2 0 E1-E2 ATPase Wzy_C PF04932.15 AII58555.1 - 0.83 9.3 9.9 2.6 7.7 9.8 1.8 1 1 0 1 1 1 0 O-Antigen ligase MNHE PF01899.16 AII58555.1 - 0.86 9.3 6.3 1.2 8.9 6.3 1.3 1 0 0 1 1 1 0 Na+/H+ ion antiporter subunit Tetraspanin PF00335.20 AII58555.1 - 1.6 8.4 5.7 2.3 7.9 5.7 1.3 1 0 0 1 1 1 0 Tetraspanin family DUF2892 PF11127.8 AII58555.1 - 1.8 8.7 9.8 0.35 10.9 4.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) FeoB_associated PF12669.7 AII58555.1 - 6.9 7.2 6.7 8.5 6.9 0.1 3.0 3 1 0 3 3 3 0 FeoB-associated Cys-rich membrane protein Dehalogenase PF13486.6 AII58556.1 - 2.3e-79 266.8 0.0 3.2e-79 266.3 0.0 1.2 1 0 0 1 1 1 1 Reductive dehalogenase subunit Fer4_16 PF13484.6 AII58556.1 - 2.2e-12 47.7 9.6 4e-12 46.9 9.6 1.5 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain TAT_signal PF10518.9 AII58556.1 - 0.00011 21.8 3.4 0.00029 20.6 3.4 1.7 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence Fer4_7 PF12838.7 AII58556.1 - 0.00045 20.8 8.3 0.001 19.6 8.3 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 AII58556.1 - 0.0071 16.1 1.4 0.0071 16.1 1.4 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_9 PF13187.6 AII58556.1 - 0.12 12.6 10.5 0.15 12.3 2.5 2.5 1 1 2 3 3 3 0 4Fe-4S dicluster domain PC_rep PF01851.22 AII58556.1 - 0.12 12.8 1.7 19 5.9 0.1 3.5 3 1 0 3 3 3 0 Proteasome/cyclosome repeat Fer4_10 PF13237.6 AII58556.1 - 0.49 10.5 9.5 2.3 8.4 9.7 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 AII58556.1 - 7 6.9 11.7 0.057 13.5 3.3 2.0 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 AII58556.1 - 8.1 7.1 13.5 5.9 7.5 9.9 2.5 2 1 1 3 3 3 0 4Fe-4S dicluster domain HATPase_c PF02518.26 AII58557.1 - 3.2e-26 92.0 0.0 8.7e-26 90.6 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 AII58557.1 - 9e-10 38.7 0.2 2.1e-09 37.5 0.2 1.7 1 0 0 1 1 1 1 PAS domain HisKA PF00512.25 AII58557.1 - 2.2e-09 37.2 4.2 3.5e-09 36.6 0.1 2.8 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 AII58557.1 - 1.8e-06 27.8 0.0 4.3e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AII58557.1 - 6.7e-06 26.1 0.2 2.6e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 PAS fold HATPase_c_3 PF13589.6 AII58557.1 - 0.00011 22.0 0.0 0.00028 20.7 0.0 1.7 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 AII58557.1 - 0.0041 17.0 0.0 0.026 14.4 0.0 2.2 1 1 1 2 2 2 1 GHKL domain HATPase_c_2 PF13581.6 AII58557.1 - 0.0066 16.4 0.0 0.021 14.8 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain SwrA PF17423.2 AII58557.1 - 0.03 14.3 0.6 0.065 13.2 0.0 1.8 2 0 0 2 2 2 0 Swarming motility protein PAS_4 PF08448.10 AII58557.1 - 0.045 14.0 0.0 0.086 13.1 0.0 1.6 1 1 0 1 1 1 0 PAS fold PAS_3 PF08447.12 AII58557.1 - 0.074 13.3 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 PAS fold SATase_N PF06426.14 AII58557.1 - 0.096 13.1 0.2 0.23 11.9 0.2 1.7 1 0 0 1 1 1 0 Serine acetyltransferase, N-terminal HPTransfase PF10090.9 AII58557.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Histidine phosphotransferase C-terminal domain CASP_C PF08172.12 AII58557.1 - 0.13 11.6 2.9 3.1 7.1 0.1 2.2 2 0 0 2 2 2 0 CASP C terminal DUF2150 PF09920.9 AII58557.1 - 0.15 12.0 1.4 0.37 10.8 0.4 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) betaPIX_CC PF16523.5 AII58557.1 - 2.3 8.1 7.6 2.2 8.2 1.1 2.9 3 0 0 3 3 3 0 betaPIX coiled coil DivIC PF04977.15 AII58557.1 - 8.7 6.2 9.7 2.3 8.0 0.5 3.2 3 0 0 3 3 3 0 Septum formation initiator Response_reg PF00072.24 AII58558.1 - 7.4e-25 87.3 0.1 1.2e-24 86.6 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 AII58558.1 - 1.2e-14 54.2 0.0 2.5e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal GerE PF00196.19 AII58558.1 - 0.061 12.9 0.0 0.59 9.7 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Virul_fac_BrkB PF03631.15 AII58559.1 - 0.00032 20.4 3.2 0.00035 20.3 3.2 1.0 1 0 0 1 1 1 1 Virulence factor BrkB Trp_oprn_chp PF09534.10 AII58559.1 - 0.13 12.1 3.9 0.26 11.0 2.2 1.9 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2892 PF11127.8 AII58559.1 - 0.22 11.6 11.0 1 9.5 0.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2892) Wzy_C PF04932.15 AII58559.1 - 0.62 9.7 5.2 0.19 11.4 1.9 1.7 2 0 0 2 2 2 0 O-Antigen ligase PorA PF11271.8 AII58560.1 - 4.9e-31 108.1 2.9 8.1e-31 107.4 2.9 1.3 1 1 0 1 1 1 1 Porin PorA CD36 PF01130.21 AII58560.1 - 1.1e-07 30.8 2.7 0.0012 17.5 0.1 2.2 1 1 1 2 2 2 2 CD36 family TMEM43 PF07787.12 AII58560.1 - 0.13 11.6 2.6 0.15 11.5 0.2 2.0 2 0 0 2 2 2 0 Transmembrane protein 43 EMP24_GP25L PF01105.24 AII58560.1 - 0.14 12.1 0.8 0.32 10.9 0.3 1.8 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF5112 PF17139.4 AII58560.1 - 0.17 11.3 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5112) ABC2_membrane_5 PF13346.6 AII58561.1 - 0.00051 19.7 4.4 0.00055 19.6 4.4 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein FUSC_2 PF13515.6 AII58561.1 - 0.0088 16.2 6.6 0.012 15.7 6.6 1.2 1 0 0 1 1 1 1 Fusaric acid resistance protein-like Wzy_C PF04932.15 AII58561.1 - 0.013 15.1 4.6 0.013 15.1 4.6 1.7 1 1 1 2 2 2 0 O-Antigen ligase AA_permease_2 PF13520.6 AII58561.1 - 0.018 13.9 6.5 0.023 13.6 6.3 1.3 1 1 0 1 1 1 0 Amino acid permease YesK PF14150.6 AII58561.1 - 0.039 14.1 5.1 0.095 12.9 1.7 2.0 2 0 0 2 2 2 0 YesK-like protein Melittin PF01372.17 AII58561.1 - 0.048 13.6 4.1 0.33 11.0 0.2 2.6 2 0 0 2 2 2 0 Melittin Glucos_trans_II PF14264.6 AII58561.1 - 0.069 12.5 5.7 0.078 12.3 5.2 1.4 1 1 0 1 1 1 0 Glucosyl transferase GtrII DUF4181 PF13789.6 AII58561.1 - 0.15 12.3 3.7 0.18 12.1 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4181) DUF2304 PF10066.9 AII58561.1 - 0.32 11.2 8.5 0.45 10.8 8.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) DUF2085 PF09858.9 AII58561.1 - 0.61 10.6 3.8 0.81 10.2 3.8 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2085) DUF1129 PF06570.11 AII58561.1 - 0.9 9.0 5.9 1.2 8.6 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) DUF983 PF06170.12 AII58561.1 - 1 9.8 7.0 2.3 8.7 3.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF983) PrgI PF12666.7 AII58561.1 - 2.4 9.0 8.5 0.12 13.1 1.0 2.0 1 1 1 2 2 2 0 PrgI family protein Phage_holin_2_3 PF16080.5 AII58561.1 - 4.2 7.2 7.5 1.3 8.9 0.9 2.8 2 1 1 3 3 3 0 Bacteriophage holin family HP1 Tetraspanin PF00335.20 AII58561.1 - 6.6 6.4 7.6 8.8 6.0 7.6 1.2 1 0 0 1 1 1 0 Tetraspanin family FeoB_associated PF12669.7 AII58561.1 - 7.7 7.0 6.9 1.2 9.6 0.3 2.5 3 0 0 3 3 3 0 FeoB-associated Cys-rich membrane protein Dehalogenase PF13486.6 AII58562.1 - 3.7e-80 269.4 0.0 5.4e-80 268.9 0.0 1.2 1 0 0 1 1 1 1 Reductive dehalogenase subunit Fer4_16 PF13484.6 AII58562.1 - 7e-09 36.5 9.3 1.2e-08 35.7 9.3 1.4 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain TAT_signal PF10518.9 AII58562.1 - 0.00021 21.0 2.8 0.00021 21.0 2.8 3.4 4 0 0 4 4 4 1 TAT (twin-arginine translocation) pathway signal sequence Fer4_9 PF13187.6 AII58562.1 - 0.00076 19.6 2.5 0.037 14.2 0.6 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AII58562.1 - 0.29 11.8 8.0 0.76 10.4 8.0 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain PDT PF00800.18 AII58563.1 - 1.3e-53 181.6 0.1 1.7e-53 181.2 0.1 1.2 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 AII58563.1 - 0.056 13.2 0.0 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 ACT domain SAM_adeno_trans PF01887.16 AII58564.1 - 7.2e-76 254.7 0.0 8.2e-76 254.5 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-l-methionine hydroxide adenosyltransferase SecG PF03840.14 AII58565.1 - 1.5e-14 53.9 9.6 1.6e-14 53.7 9.6 1.0 1 0 0 1 1 1 1 Preprotein translocase SecG subunit DUF131 PF01998.17 AII58565.1 - 0.031 13.9 0.4 0.031 13.9 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function DUF131 Pox_EPC_I2-L1 PF12575.8 AII58565.1 - 2.7 8.3 6.9 0.41 10.9 0.8 2.0 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 Sigma_reg_N PF13800.6 AII58565.1 - 2.7 8.3 10.0 11 6.4 4.0 2.1 2 0 0 2 2 2 0 Sigma factor regulator N-terminal TRIQK PF15168.6 AII58565.1 - 5.8 6.9 7.1 0.18 11.7 0.8 1.7 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family GatB_N PF02934.15 AII58566.1 - 8.5e-111 369.7 0.0 1.1e-110 369.3 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 AII58566.1 - 4.7e-40 136.9 1.1 7e-40 136.3 1.1 1.3 1 0 0 1 1 1 1 GatB domain DUF4405 PF14358.6 AII58567.1 - 0.0022 18.5 8.2 0.0056 17.2 8.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4405) DUF998 PF06197.13 AII58567.1 - 0.046 13.3 2.0 0.047 13.3 2.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF998) DUF1656 PF07869.12 AII58567.1 - 0.081 12.9 0.1 0.081 12.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) Fer4 PF00037.27 AII58568.1 - 3.1e-13 48.9 11.6 1.7e-06 27.6 2.0 2.1 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AII58568.1 - 9.7e-11 42.1 33.8 3e-06 27.7 13.5 2.0 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_21 PF14697.6 AII58568.1 - 2.2e-10 40.5 9.1 2.7e-10 40.2 9.1 1.1 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AII58568.1 - 3.5e-08 33.5 10.7 6.3e-08 32.7 10.8 1.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AII58568.1 - 7.5e-08 32.4 12.5 0.00075 19.6 3.8 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AII58568.1 - 8e-08 33.1 10.2 0.00028 21.8 2.5 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 AII58568.1 - 3.5e-07 29.9 11.8 0.0017 18.3 2.7 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 AII58568.1 - 3.6e-06 26.8 11.4 0.00042 20.3 3.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 AII58568.1 - 1e-05 26.0 6.1 0.011 16.2 0.5 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_22 PF17179.4 AII58568.1 - 0.0018 19.1 4.4 0.55 11.1 0.6 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AII58568.1 - 0.028 14.8 14.5 0.12 12.9 2.3 2.1 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 AII58568.1 - 0.066 13.8 16.2 0.67 10.6 4.9 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_13 PF13370.6 AII58568.1 - 0.22 12.1 11.9 0.44 11.1 1.9 2.2 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 AII58568.1 - 0.26 11.5 10.1 0.29 11.3 0.9 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 AII58568.1 - 0.32 11.8 9.7 0.48 11.2 0.4 2.4 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.7 AII58568.1 - 0.75 10.9 17.3 1.7 9.8 5.7 2.5 2 1 0 2 2 2 0 4Fe-4S binding domain MerR_1 PF13411.6 AII58569.1 - 4e-18 65.3 0.0 5.6e-17 61.6 0.0 2.2 2 0 0 2 2 2 1 MerR HTH family regulatory protein MerR PF00376.23 AII58569.1 - 2.2e-08 33.7 0.0 4.9e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 MerR family regulatory protein AbiEi_4 PF13338.6 AII58569.1 - 0.00012 22.1 0.0 0.17 12.0 0.0 2.5 2 0 0 2 2 2 2 Transcriptional regulator, AbiEi antitoxin MerR_2 PF13591.6 AII58569.1 - 0.0029 17.4 0.0 0.12 12.2 0.0 2.8 2 1 1 3 3 3 1 MerR HTH family regulatory protein HTH_17 PF12728.7 AII58569.1 - 0.0033 17.6 0.0 0.019 15.1 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_IclR PF09339.10 AII58569.1 - 0.025 14.4 0.1 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_24 PF13412.6 AII58569.1 - 0.21 11.2 0.0 0.21 11.2 0.0 3.4 4 1 0 4 4 4 0 Winged helix-turn-helix DNA-binding SQHop_cyclase_C PF13243.6 AII58570.1 - 0.0016 17.6 0.0 0.33 10.0 0.0 2.3 2 0 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain DUF2178 PF09946.9 AII58571.1 - 0.0026 17.9 0.4 0.0031 17.7 0.4 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2178) DUF2160 PF09928.9 AII58571.1 - 0.0081 16.5 0.2 4.8 7.6 0.0 2.3 2 1 0 2 2 2 2 Predicted small integral membrane protein (DUF2160) PRNT PF15174.6 AII58571.1 - 0.033 14.2 0.1 0.074 13.1 0.1 1.5 1 0 0 1 1 1 0 Prion-related protein testis-specific MurJ PF03023.14 AII58571.1 - 0.097 11.2 2.5 0.11 11.1 2.5 1.0 1 0 0 1 1 1 0 Lipid II flippase MurJ Kindlin_2_N PF18124.1 AII58572.1 - 0.024 14.8 1.0 0.17 12.1 0.4 2.2 2 0 0 2 2 2 0 Kindlin-2 N-terminal domain Oxidored_q6 PF01058.22 AII58573.1 - 1.9e-17 63.3 0.0 2.4e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Complex1_49kDa PF00346.19 AII58574.1 - 1.1e-41 142.7 0.0 4e-34 117.9 0.0 2.1 1 1 1 2 2 2 2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Complex1_30kDa PF00329.19 AII58574.1 - 4e-11 43.6 0.0 7.9e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit NiFeSe_Hases PF00374.19 AII58574.1 - 7.5e-05 21.8 0.0 0.066 12.1 0.0 2.1 2 0 0 2 2 2 2 Nickel-dependent hydrogenase Proton_antipo_M PF00361.20 AII58575.1 - 1.9e-47 161.9 29.4 1.9e-47 161.9 29.4 2.7 2 1 1 3 3 3 2 Proton-conducting membrane transporter TraQ PF09679.10 AII58576.1 - 0.47 10.4 4.0 1.3 9.0 1.8 2.7 1 1 1 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) NADHdh PF00146.21 AII58577.1 - 3.1e-32 112.1 22.0 4e-32 111.7 22.0 1.0 1 0 0 1 1 1 1 NADH dehydrogenase Proton_antipo_M PF00361.20 AII58578.1 - 1.5e-50 172.0 35.3 1.5e-50 172.0 35.3 2.8 2 1 1 3 3 3 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 AII58578.1 - 1.8e-05 24.7 1.7 1.8e-05 24.7 1.7 3.7 2 1 1 3 3 3 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus MGS PF02142.22 AII58579.1 - 3.6e-12 46.3 0.0 4.5e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 MGS-like domain PrpR_N PF06506.11 AII58579.1 - 0.11 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Propionate catabolism activator Zn-ribbon_8 PF09723.10 AII58580.1 - 2.9e-09 36.9 3.1 4e-09 36.5 3.1 1.2 1 0 0 1 1 1 1 Zinc ribbon domain Elf1 PF05129.13 AII58580.1 - 0.0048 16.9 1.4 0.0092 16.0 1.4 1.5 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf_C2H2_10 PF18414.1 AII58580.1 - 0.0053 16.3 4.2 0.011 15.2 0.5 2.4 2 0 0 2 2 2 1 C2H2 type zinc-finger DUF4379 PF14311.6 AII58580.1 - 0.0069 16.7 1.3 0.31 11.4 0.4 2.2 2 0 0 2 2 2 1 Probable Zinc-ribbon domain TF_Zn_Ribbon PF08271.12 AII58580.1 - 0.017 14.6 4.5 0.49 10.0 0.1 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding Anti-TRAP PF15777.5 AII58580.1 - 0.029 14.3 0.9 0.064 13.2 0.9 1.6 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf_UBZ PF18439.1 AII58580.1 - 0.035 13.7 2.9 1.1 8.9 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-ribbon_3 PF13248.6 AII58580.1 - 0.038 13.4 5.1 0.41 10.1 0.1 2.4 2 1 0 2 2 2 0 zinc-ribbon domain zf-UDP PF14569.6 AII58580.1 - 0.039 14.1 4.2 0.067 13.3 4.2 1.5 1 1 0 1 1 1 0 Zinc-binding RING-finger MCM_OB PF17207.3 AII58580.1 - 0.041 13.7 1.9 0.051 13.4 1.9 1.2 1 0 0 1 1 1 0 MCM OB domain zinc_ribbon_9 PF14369.6 AII58580.1 - 0.068 13.4 2.1 1.1 9.5 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon Nudix_N_2 PF14803.6 AII58580.1 - 0.083 12.8 2.9 0.22 11.5 2.1 2.0 2 0 0 2 2 2 0 Nudix N-terminal HypA PF01155.19 AII58580.1 - 0.31 11.1 1.8 0.41 10.7 1.8 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-TFIIB PF13453.6 AII58580.1 - 0.74 9.2 5.7 2.7 7.4 4.2 2.1 1 1 1 2 2 2 0 Transcription factor zinc-finger zinc_ribbon_4 PF13717.6 AII58580.1 - 1.2 9.2 8.3 25 4.9 1.1 2.6 2 1 0 2 2 2 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 AII58580.1 - 1.4 8.9 7.0 1.8 8.5 1.9 2.2 1 1 1 2 2 2 0 Putative transposase DNA-binding domain MS_channel PF00924.18 AII58581.1 - 5.1e-39 134.0 1.7 5.1e-39 134.0 1.7 3.0 3 0 0 3 3 3 1 Mechanosensitive ion channel DUF4271 PF14093.6 AII58581.1 - 0.071 13.0 4.1 0.13 12.2 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) SirB PF04247.12 AII58581.1 - 0.19 11.9 6.9 0.029 14.4 1.5 2.4 1 1 1 2 2 2 0 Invasion gene expression up-regulator, SirB TetR_N PF00440.23 AII58582.1 - 1e-17 63.7 0.0 1.9e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family LacI PF00356.21 AII58582.1 - 0.027 14.3 0.0 0.071 12.9 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_23 PF13384.6 AII58582.1 - 0.029 14.2 0.0 0.072 12.9 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_40 PF14493.6 AII58582.1 - 0.032 14.7 0.0 0.054 14.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 AII58582.1 - 0.065 12.9 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Tnp_1_2 PF13022.6 AII58582.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.5 1 1 0 1 1 1 0 Helix-turn-helix of insertion element transposase Epimerase PF01370.21 AII58583.1 - 1.1e-22 80.6 0.0 1.8e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AII58583.1 - 1.9e-17 63.2 0.0 2.4e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 AII58583.1 - 7.2e-15 55.3 0.0 9.9e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 AII58583.1 - 4.6e-10 39.4 0.0 1.6e-09 37.6 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 AII58583.1 - 2.4e-08 33.8 0.0 1.1e-07 31.6 0.0 2.1 2 1 1 3 3 3 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 AII58583.1 - 3.1e-08 33.1 0.1 6.8e-06 25.4 0.2 2.8 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 AII58583.1 - 3.1e-07 29.8 0.0 0.00033 19.9 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 AII58583.1 - 0.00012 21.3 0.0 0.00021 20.5 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain DapB_N PF01113.20 AII58583.1 - 0.017 15.3 0.2 0.029 14.5 0.2 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 AII58583.1 - 0.024 14.1 0.5 0.15 11.5 0.3 2.2 2 1 0 2 2 2 0 short chain dehydrogenase KR PF08659.10 AII58583.1 - 0.097 12.6 0.6 1.8 8.4 0.6 2.4 1 1 0 1 1 1 0 KR domain NAD_binding_10 PF13460.6 AII58584.1 - 5.8e-10 39.4 0.0 8.4e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 AII58584.1 - 5.7e-08 32.5 0.0 7.7e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 AII58584.1 - 1e-06 28.0 0.0 6.4e-06 25.4 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 AII58584.1 - 0.00062 19.4 0.1 0.0017 18.0 0.1 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 AII58584.1 - 0.079 12.1 0.0 0.17 11.0 0.1 1.5 2 0 0 2 2 2 0 Male sterility protein LpxI_N PF17930.1 AII58584.1 - 0.11 12.4 0.0 14 5.6 0.0 2.3 1 1 1 2 2 2 0 LpxI N-terminal domain GDP_Man_Dehyd PF16363.5 AII58584.1 - 0.15 11.4 0.1 0.23 10.8 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase AhpC-TSA PF00578.21 AII58585.1 - 5.7e-31 107.0 0.0 7.9e-31 106.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 AII58585.1 - 2.6e-17 62.4 0.7 4.2e-17 61.7 0.7 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 AII58585.1 - 3e-15 56.2 0.0 4.2e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.14 AII58585.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 SCO1/SenC HTH_45 PF14947.6 AII58586.1 - 9.9e-05 22.3 0.0 0.00012 22.0 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix MarR_2 PF12802.7 AII58586.1 - 0.001 18.9 0.0 0.0011 18.7 0.0 1.1 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 AII58586.1 - 0.0042 16.9 0.0 0.0051 16.7 0.0 1.1 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DUF4423 PF14394.6 AII58586.1 - 0.038 13.7 0.0 0.043 13.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) FaeA PF04703.12 AII58586.1 - 0.13 12.7 0.0 0.16 12.4 0.0 1.2 1 0 0 1 1 1 0 FaeA-like protein HemN_C PF06969.16 AII58586.1 - 0.15 12.1 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 HemN C-terminal domain TMEM43 PF07787.12 AII58587.1 - 1 8.7 3.9 1.1 8.6 3.9 1.0 1 0 0 1 1 1 0 Transmembrane protein 43 zf-TFIIB PF13453.6 AII58588.1 - 1.6e-23 81.8 3.5 1.9e-14 52.7 0.6 2.2 2 0 0 2 2 2 2 Transcription factor zinc-finger TF_Zn_Ribbon PF08271.12 AII58588.1 - 0.00091 18.7 3.1 0.0016 17.9 0.3 2.2 2 0 0 2 2 2 1 TFIIB zinc-binding zf-C3HC4_3 PF13920.6 AII58588.1 - 0.0035 17.2 5.1 0.13 12.2 0.5 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Cytochrom_c3_2 PF14537.6 AII58588.1 - 0.011 16.2 0.5 0.029 14.8 0.6 1.7 1 1 0 1 1 1 0 Cytochrome c3 Prok-RING_4 PF14447.6 AII58588.1 - 0.011 15.6 5.1 0.15 12.0 0.1 2.7 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 DZR PF12773.7 AII58588.1 - 0.014 15.4 1.6 4.1 7.5 0.1 2.3 2 0 0 2 2 2 0 Double zinc ribbon TackOD1 PF18551.1 AII58588.1 - 0.02 14.6 0.3 0.03 14.0 0.3 1.3 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 RNHCP PF12647.7 AII58588.1 - 0.035 14.1 1.9 2.6 8.1 0.2 2.2 2 0 0 2 2 2 0 RNHCP domain zinc-ribbons_6 PF07191.12 AII58588.1 - 0.059 13.3 3.9 3.8 7.6 0.1 2.5 2 1 0 2 2 2 0 zinc-ribbons zf-RRPl_C4 PF17026.5 AII58588.1 - 0.087 12.9 0.3 0.13 12.4 0.3 1.3 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type Rad50_zn_hook PF04423.14 AII58588.1 - 0.12 12.3 0.1 0.12 12.3 0.1 3.1 4 0 0 4 4 4 0 Rad50 zinc hook motif zf-piccolo PF05715.13 AII58588.1 - 0.19 11.9 1.6 5.4 7.2 0.2 2.2 2 0 0 2 2 2 0 Piccolo Zn-finger zf-C2H2_4 PF13894.6 AII58588.1 - 0.2 12.6 2.4 53 5.0 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 AII58588.1 - 0.39 10.9 9.4 6.4 7.0 2.0 3.3 3 1 0 3 3 3 0 Zinc ribbon domain zf-XS PF03470.14 AII58588.1 - 0.47 10.8 3.1 47 4.4 0.2 3.3 3 0 0 3 3 3 0 XS zinc finger domain zf-C4_Topoisom PF01396.19 AII58588.1 - 0.69 9.7 6.4 5.2 6.9 0.1 3.3 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger YdjO PF14169.6 AII58588.1 - 0.74 9.6 0.1 0.74 9.6 0.1 2.9 2 1 1 3 3 3 0 Cold-inducible protein YdjO zf-RING_5 PF14634.6 AII58588.1 - 0.99 9.4 6.9 2.5 8.2 0.1 2.7 2 1 0 2 2 2 0 zinc-RING finger domain zf-C2H2_9 PF16293.5 AII58588.1 - 1.3 8.9 3.4 13 5.7 0.1 3.1 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) Prok-RING_1 PF14446.6 AII58588.1 - 2.7 8.0 7.3 1.4 8.9 0.1 2.7 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 zf-Di19 PF05605.12 AII58588.1 - 2.9 8.2 9.1 2.4 8.5 0.6 3.0 1 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 AII58588.1 - 3.9 7.9 6.4 67 3.9 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Auto_anti-p27 PF06677.12 AII58588.1 - 6 7.1 7.2 10 6.4 1.9 2.5 2 1 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) LemA PF04011.12 AII58589.1 - 9.1e-64 213.8 6.8 1.1e-63 213.6 6.8 1.0 1 0 0 1 1 1 1 LemA family MLANA PF14991.6 AII58589.1 - 0.0038 17.5 0.5 0.011 16.0 0.2 1.9 1 1 2 3 3 3 1 Protein melan-A DUF1031 PF06275.11 AII58589.1 - 0.086 13.1 0.3 5.1 7.4 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1031) DUF3492 PF11997.8 AII58589.1 - 0.1 12.3 0.8 0.13 12.0 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) GD_N PF16030.5 AII58589.1 - 0.17 12.2 1.0 0.75 10.1 0.1 2.1 2 0 0 2 2 2 0 Serine protease gd N-terminus Peptidase_M48 PF01435.18 AII58590.1 - 4.3e-38 131.1 0.0 7.6e-38 130.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 AII58590.1 - 0.00086 18.6 0.1 0.0055 16.0 0.0 2.0 2 0 0 2 2 2 1 BlaR1 peptidase M56 SprT-like PF10263.9 AII58590.1 - 0.013 15.3 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 SprT-like family MgtE PF01769.16 AII58590.1 - 0.07 13.5 4.3 3.1 8.2 0.7 2.2 2 0 0 2 2 2 0 Divalent cation transporter Phage_holin_3_6 PF07332.11 AII58590.1 - 0.07 13.2 5.8 0.58 10.2 1.1 2.4 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III ABC_export PF16962.5 AII58590.1 - 0.88 7.9 5.6 0.46 8.9 0.2 2.0 2 0 0 2 2 2 0 Putative ABC exporter DUF2207 PF09972.9 AII58590.1 - 1.8 7.2 5.1 18 3.9 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Hexapep PF00132.24 AII58591.1 - 1.1e-13 50.4 9.5 2e-08 33.6 5.5 2.6 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 AII58591.1 - 0.00013 21.7 6.1 0.00013 21.7 6.1 3.2 2 1 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase SATase_N PF06426.14 AII58591.1 - 0.011 16.1 0.0 0.034 14.5 0.0 1.8 2 0 0 2 2 2 0 Serine acetyltransferase, N-terminal CutA1 PF03091.15 AII58592.1 - 2.6e-34 117.0 0.2 3e-34 116.8 0.2 1.0 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein NadA PF02445.16 AII58593.1 - 4.7e-122 406.8 0.7 5.3e-122 406.7 0.7 1.0 1 0 0 1 1 1 1 Quinolinate synthetase A protein Methyltransf_25 PF13649.6 AII58594.1 - 7.2e-23 81.1 0.0 9.9e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 AII58594.1 - 1.4e-22 80.2 0.0 1.8e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 AII58594.1 - 8.4e-19 68.0 0.0 1.2e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 AII58594.1 - 8.8e-14 52.1 0.0 1.3e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 AII58594.1 - 5e-13 49.1 0.0 6.2e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 AII58594.1 - 2.1e-12 47.2 0.0 2.3e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 AII58594.1 - 3e-05 23.4 0.0 4.2e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase RrnaAD PF00398.20 AII58594.1 - 0.0002 20.5 0.0 0.00033 19.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase FtsJ PF01728.19 AII58594.1 - 0.00077 19.6 0.1 0.0015 18.7 0.1 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 AII58594.1 - 0.0016 18.1 0.0 0.0033 17.1 0.0 1.4 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F MTS PF05175.14 AII58594.1 - 0.0044 16.6 0.1 0.0075 15.8 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 AII58594.1 - 0.0052 16.5 0.0 0.0083 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 AII58594.1 - 0.018 14.6 0.0 0.026 14.1 0.0 1.1 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_5 PF01795.19 AII58594.1 - 0.026 14.0 0.0 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 MraW methylase family N6_N4_Mtase PF01555.18 AII58594.1 - 0.039 13.7 0.0 1 9.0 0.0 2.2 2 0 0 2 2 2 0 DNA methylase Methyltransf_32 PF13679.6 AII58594.1 - 0.047 13.7 0.0 0.065 13.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.18 AII58594.1 - 0.058 13.7 0.0 0.09 13.0 0.0 1.2 1 0 0 1 1 1 0 TrkA-N domain Met_10 PF02475.16 AII58594.1 - 0.065 13.0 0.0 0.087 12.6 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein DOT1 PF08123.13 AII58594.1 - 0.078 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 PrmA PF06325.13 AII58594.1 - 0.1 12.0 0.1 0.18 11.2 0.0 1.3 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) AIRS_C PF02769.22 AII58595.1 - 2e-20 73.5 0.4 3.4e-20 72.8 0.4 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 AII58595.1 - 1.9e-09 38.1 0.0 5.4e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Rrf2 PF02082.20 AII58596.1 - 3.1e-24 85.1 0.0 4.3e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator HrcA_DNA-bdg PF03444.15 AII58596.1 - 0.066 12.9 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding ApbE PF02424.15 AII58597.1 - 1.2e-73 247.9 0.0 1.4e-73 247.6 0.0 1.0 1 0 0 1 1 1 1 ApbE family TAT_signal PF10518.9 AII58597.1 - 0.0011 18.8 1.1 0.0011 18.8 1.1 2.1 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence UCR_Fe-S_N PF10399.9 AII58597.1 - 0.012 14.9 0.4 0.012 14.9 0.4 1.6 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Fer4_5 PF12801.7 AII58598.1 - 1.7e-13 50.3 10.9 1.3e-09 37.8 3.1 4.8 5 0 0 5 5 5 2 4Fe-4S binding domain FMN_bind PF04205.14 AII58598.1 - 3.7e-09 37.0 0.0 6.3e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 FMN-binding domain Fer4_5 PF12801.7 AII58599.1 - 9.5e-12 44.7 12.7 7.3e-07 29.0 3.9 4.0 4 0 0 4 4 4 2 4Fe-4S binding domain FMN_bind PF04205.14 AII58599.1 - 6.6e-08 33.0 0.0 1.3e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 FMN-binding domain TMEM208_SND2 PF05620.11 AII58599.1 - 1.3 8.8 4.8 1.1 9.1 0.4 2.6 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 TatC PF00902.18 AII58600.1 - 4.1e-53 180.3 19.1 4.8e-53 180.1 19.1 1.0 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) DUF2929 PF11151.8 AII58600.1 - 0.45 10.8 16.3 0.66 10.3 0.3 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2929) MttA_Hcf106 PF02416.16 AII58601.1 - 1.3e-12 46.8 0.1 1.5e-12 46.6 0.1 1.2 1 0 0 1 1 1 1 mttA/Hcf106 family MttA_Hcf106 PF02416.16 AII58602.1 - 1.4e-10 40.4 2.7 1.6e-10 40.1 2.7 1.4 1 1 0 1 1 1 1 mttA/Hcf106 family MttA_Hcf106 PF02416.16 AII58603.1 - 1.6e-15 56.1 0.8 1.9e-15 55.9 0.8 1.1 1 0 0 1 1 1 1 mttA/Hcf106 family Pterin_bind PF00809.22 AII58604.1 - 5e-78 262.2 0.0 5.7e-78 262.0 0.0 1.0 1 0 0 1 1 1 1 Pterin binding enzyme PEP_mutase PF13714.6 AII58604.1 - 0.0038 16.7 0.3 24 4.2 0.0 3.7 2 2 2 4 4 4 3 Phosphoenolpyruvate phosphomutase HPPK PF01288.20 AII58605.1 - 3.2e-37 127.5 0.0 3.9e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) PTPS PF01242.19 AII58606.1 - 1.9e-36 124.7 0.0 2.1e-36 124.6 0.0 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase RecA PF00154.21 AII58607.1 - 8.6e-129 428.6 1.2 1e-128 428.3 1.2 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 AII58607.1 - 1.8e-13 50.3 0.1 1.6e-12 47.3 0.1 1.9 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 AII58607.1 - 1.4e-10 40.9 1.7 1.1e-08 34.7 1.7 2.8 1 1 0 1 1 1 1 KaiC ATPase_2 PF01637.18 AII58607.1 - 9.9e-06 25.6 0.0 1.9e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 AII58607.1 - 1.3e-05 25.5 0.0 2.5e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 AII58607.1 - 4.6e-05 23.2 0.0 9e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 AII58607.1 - 6.2e-05 23.4 0.1 0.00013 22.4 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 AII58607.1 - 0.00021 20.9 0.1 0.038 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 AII58607.1 - 0.00029 21.4 0.0 0.00064 20.3 0.0 1.8 1 1 0 1 1 1 1 ABC transporter NACHT PF05729.12 AII58607.1 - 0.00083 19.3 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 NACHT domain CobU PF02283.16 AII58607.1 - 0.0027 17.3 0.0 0.012 15.2 0.0 2.0 2 1 0 2 2 2 1 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_14 PF13173.6 AII58607.1 - 0.003 17.6 0.0 0.0054 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_35 PF14516.6 AII58607.1 - 0.0045 15.9 0.0 0.0075 15.1 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain IstB_IS21 PF01695.17 AII58607.1 - 0.0049 16.6 0.0 0.25 11.0 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein cobW PF02492.19 AII58607.1 - 0.0069 16.0 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 AII58607.1 - 0.011 16.1 0.1 0.018 15.4 0.1 1.3 1 0 0 1 1 1 0 AAA ATPase domain CLP1_P PF16575.5 AII58607.1 - 0.012 15.4 0.0 0.03 14.1 0.0 1.7 2 0 0 2 2 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop TrwB_AAD_bind PF10412.9 AII58607.1 - 0.013 14.4 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ATP-synt_ab PF00006.25 AII58607.1 - 0.027 14.1 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.14 AII58607.1 - 0.034 14.1 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 AII58607.1 - 0.036 14.6 0.0 0.069 13.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 AII58607.1 - 0.039 13.7 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 AII58607.1 - 0.044 14.2 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 AII58607.1 - 0.044 13.0 0.0 0.066 12.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 AII58607.1 - 0.046 13.9 0.0 0.09 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AII58607.1 - 0.086 13.2 0.1 0.3 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain MipZ PF09140.11 AII58607.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 ATPase MipZ AAA_13 PF13166.6 AII58607.1 - 0.24 10.0 0.0 0.35 9.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain RecX PF02631.16 AII58608.1 - 2e-27 96.1 0.6 9.6e-26 90.6 0.2 1.8 1 1 1 2 2 2 2 RecX family DUF494 PF04361.13 AII58608.1 - 0.0049 16.8 0.0 0.29 11.0 0.0 2.7 1 1 2 3 3 3 1 Protein of unknown function (DUF494) MarR_2 PF12802.7 AII58608.1 - 0.019 14.9 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 MarR family Sucrose_synth PF00862.19 AII58608.1 - 0.065 11.5 0.0 0.089 11.1 0.0 1.2 1 0 0 1 1 1 0 Sucrose synthase DUF3783 PF12646.7 AII58608.1 - 0.11 12.5 0.0 0.37 10.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) DUF3552 PF12072.8 AII58609.1 - 2.4e-44 151.2 23.5 5.1e-44 150.1 23.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) HD PF01966.22 AII58609.1 - 1.7e-17 63.8 0.8 4.2e-17 62.5 0.0 2.1 2 1 0 2 2 2 1 HD domain KH_1 PF00013.29 AII58609.1 - 9.8e-09 34.9 0.0 3.3e-08 33.2 0.0 2.0 1 0 0 1 1 1 1 KH domain HDOD PF08668.12 AII58609.1 - 2.3e-06 27.2 0.4 0.0071 15.8 0.0 2.6 1 1 1 2 2 2 2 HDOD domain KH_4 PF13083.6 AII58609.1 - 0.00069 19.4 0.4 0.007 16.2 0.1 2.8 2 1 0 2 2 2 1 KH domain KH_2 PF07650.17 AII58609.1 - 0.0016 18.3 0.0 0.011 15.5 0.0 2.6 1 0 0 1 1 1 1 KH domain LapA_dom PF06305.11 AII58609.1 - 0.0039 17.0 0.6 0.0039 17.0 0.6 3.1 2 1 0 2 2 1 1 Lipopolysaccharide assembly protein A domain DUF4407 PF14362.6 AII58609.1 - 0.014 14.8 12.2 0.031 13.6 12.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LMBR1 PF04791.16 AII58609.1 - 0.31 9.9 3.4 0.49 9.2 3.4 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein Borrelia_P83 PF05262.11 AII58609.1 - 0.66 8.4 20.1 0.99 7.8 20.1 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein TMPIT PF07851.13 AII58609.1 - 1.5 8.0 11.6 2.5 7.3 11.6 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF1664 PF07889.12 AII58609.1 - 1.5 8.9 7.4 5.4 7.1 7.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 AII58609.1 - 1.6 8.2 17.3 3.7 7.0 17.1 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit FliD_N PF02465.18 AII58609.1 - 2 9.2 7.1 2.2 9.0 5.0 2.2 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF668 PF05003.12 AII58609.1 - 4 8.0 9.2 1.1 9.8 1.4 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF668) PepSY_TM_like_2 PF16357.5 AII58609.1 - 5.5 6.9 7.1 81 3.1 7.1 2.3 1 1 0 1 1 1 0 Putative PepSY_TM-like Spc7 PF08317.11 AII58609.1 - 6.8 5.5 26.3 9.6 5.0 25.4 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 AII58609.1 - 8.2 4.2 13.5 12 3.6 13.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YmdB PF13277.6 AII58610.1 - 5.8e-100 333.8 0.0 6.5e-100 333.6 0.0 1.0 1 0 0 1 1 1 1 YmdB-like protein Metallophos PF00149.28 AII58610.1 - 2.1e-05 25.2 0.0 3.7e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PHP PF02811.19 AII58611.1 - 6.8e-10 39.5 0.0 1.2e-09 38.7 0.0 1.7 1 1 0 1 1 1 1 PHP domain PHP_C PF13263.6 AII58611.1 - 0.087 12.6 0.1 0.3 10.9 0.0 1.9 2 0 0 2 2 2 0 PHP-associated G3P_acyltransf PF02660.15 AII58612.1 - 1.3e-35 122.9 16.5 1.7e-35 122.5 16.5 1.1 1 0 0 1 1 1 1 Glycerol-3-phosphate acyltransferase HhH-GPD PF00730.25 AII58613.1 - 3.9e-13 49.8 0.0 6.3e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 AII58613.1 - 0.00074 19.3 0.2 0.0027 17.5 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif DNA_pol_lambd_f PF10391.9 AII58613.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda POTRA PF07244.15 AII58613.1 - 0.2 12.2 0.0 0.34 11.5 0.0 1.3 1 0 0 1 1 1 0 Surface antigen variable number repeat TrmO PF01980.16 AII58614.1 - 1.9e-30 105.5 0.0 2.2e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 tRNA-methyltransferase O HMGL-like PF00682.19 AII58615.1 - 1.4e-43 149.4 0.1 1.9e-43 149.0 0.1 1.2 1 0 0 1 1 1 1 HMGL-like YycC PF14174.6 AII58615.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 YycC-like protein HIT PF01230.23 AII58616.1 - 9.3e-10 39.1 0.0 1.2e-09 38.8 0.0 1.2 1 0 0 1 1 1 1 HIT domain CwfJ_C_1 PF04677.15 AII58616.1 - 0.00019 21.3 0.0 0.0003 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DcpS_C PF11969.8 AII58616.1 - 0.012 16.1 0.0 0.018 15.5 0.0 1.2 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding MazE_antitoxin PF04014.18 AII58617.1 - 1.5e-05 24.8 0.0 2.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin PrlF_antitoxin PF15937.5 AII58617.1 - 0.028 14.9 0.0 0.04 14.4 0.0 1.3 1 1 0 1 1 1 0 prlF antitoxin for toxin YhaV_toxin DUF4055 PF13264.6 AII58617.1 - 0.032 14.4 0.1 0.032 14.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) T3SS_needle_E PF08988.10 AII58617.1 - 0.045 13.9 0.7 0.062 13.5 0.7 1.2 1 0 0 1 1 1 0 Type III secretion system, cytoplasmic E component of needle Plasmid_RAQPRD PF09686.10 AII58617.1 - 0.047 13.9 1.2 0.059 13.6 1.2 1.2 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) YbjQ_1 PF01906.17 AII58618.1 - 2.9e-39 133.9 4.1 3.2e-39 133.7 4.1 1.0 1 0 0 1 1 1 1 Putative heavy-metal-binding SeleniumBinding PF11524.8 AII58618.1 - 0.0016 18.8 0.2 0.0029 18.0 0.1 1.6 2 0 0 2 2 2 1 Selenium binding protein DUF3619 PF12279.8 AII58618.1 - 0.14 12.5 0.1 0.16 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) PLDc_N PF13396.6 AII58619.1 - 8.2e-13 48.1 8.3 1.4e-12 47.3 8.3 1.4 1 0 0 1 1 1 1 Phospholipase_D-nuclease N-terminal DUF3382 PF11862.8 AII58619.1 - 0.021 15.1 1.3 0.024 14.9 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) DuoxA PF10204.9 AII58619.1 - 0.04 12.9 1.9 0.042 12.9 1.9 1.0 1 0 0 1 1 1 0 Dual oxidase maturation factor Pox_A14 PF05767.12 AII58619.1 - 0.075 13.2 0.7 0.086 13.0 0.7 1.1 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 SdpI PF13630.6 AII58619.1 - 0.11 12.6 4.5 0.14 12.3 4.5 1.2 1 0 0 1 1 1 0 SdpI/YhfL protein family DUF3267 PF11667.8 AII58619.1 - 0.28 11.5 3.7 0.41 10.9 3.7 1.3 1 1 0 1 1 1 0 Putative zincin peptidase DUF4870 PF09685.10 AII58619.1 - 0.42 10.7 6.4 1.5 9.0 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4870) OST3_OST6 PF04756.13 AII58619.1 - 0.54 9.6 3.2 0.58 9.5 3.2 1.0 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Insulin_TMD PF17870.1 AII58619.1 - 8.2 6.6 11.0 0.9 9.7 1.1 2.4 2 1 0 2 2 2 0 Insulin receptor trans-membrane segment ABC_tran PF00005.27 AII58620.1 - 1.8e-26 93.3 0.0 2.9e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AII58620.1 - 1.2e-10 41.7 0.0 6.1e-06 26.3 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 AII58620.1 - 3.3e-09 37.4 0.1 5.4e-09 36.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) AAA_23 PF13476.6 AII58620.1 - 0.0014 19.1 0.2 0.0029 18.1 0.2 1.4 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 AII58620.1 - 0.031 13.7 0.0 1.6 8.1 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_27 PF13514.6 AII58620.1 - 0.035 13.7 0.1 0.064 12.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 AII58620.1 - 0.047 12.3 0.1 1 7.9 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 AII58620.1 - 0.053 13.9 0.1 0.44 11.0 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 AII58620.1 - 0.12 12.7 0.3 1.8 8.8 0.1 2.4 1 1 1 2 2 2 0 AAA domain ABC2_membrane_2 PF12679.7 AII58621.1 - 4.3e-15 55.8 17.6 1.1e-14 54.4 17.6 1.6 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 AII58621.1 - 5.2e-09 35.7 24.0 5.2e-09 35.7 24.0 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_5 PF13346.6 AII58621.1 - 2.6e-08 33.7 19.5 2.4e-07 30.5 13.7 2.3 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 AII58621.1 - 3.1e-08 33.8 16.8 7.1e-08 32.6 16.8 1.6 1 1 0 1 1 1 1 ABC-2 family transporter protein Flg_new PF09479.10 AII58622.1 - 1.6e-09 37.8 9.7 0.0025 17.9 2.2 3.8 4 0 0 4 4 4 3 Listeria-Bacteroides repeat domain (List_Bact_rpt) DUF296 PF03479.15 AII58623.1 - 7.6e-13 48.8 0.0 8.8e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Plants and Prokaryotes Conserved (PCC) domain Desulfoferrod_N PF06397.12 AII58624.1 - 3.6e-17 61.7 6.2 4.3e-17 61.4 6.2 1.1 1 0 0 1 1 1 1 Desulfoferrodoxin, N-terminal domain DUF3449 PF11931.8 AII58624.1 - 0.013 15.3 0.1 0.018 14.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) YhfH PF14149.6 AII58624.1 - 0.065 13.2 2.0 0.57 10.2 0.2 2.2 2 0 0 2 2 2 0 YhfH-like protein 2TM PF13239.6 AII58625.1 - 0.00055 20.2 2.1 0.00058 20.1 2.1 1.1 1 0 0 1 1 1 1 2TM domain DUF4870 PF09685.10 AII58625.1 - 0.039 14.1 2.9 0.042 13.9 2.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4870) Phage_holin_3_6 PF07332.11 AII58625.1 - 0.11 12.6 1.4 0.12 12.4 1.4 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4131 PF13567.6 AII58625.1 - 0.13 11.9 0.5 0.15 11.7 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Wzy_C PF04932.15 AII58625.1 - 0.13 11.8 1.5 0.14 11.8 1.5 1.1 1 0 0 1 1 1 0 O-Antigen ligase FeoB_associated PF12669.7 AII58625.1 - 0.39 11.2 2.2 4.1 7.9 0.0 2.2 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein DUF2207 PF09972.9 AII58625.1 - 0.8 8.4 2.1 0.87 8.3 2.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SPT_ssu-like PF11779.8 AII58625.1 - 4.5 7.0 7.9 1.7 8.3 5.5 1.6 1 1 1 2 2 2 0 Small subunit of serine palmitoyltransferase-like Semialdhyde_dh PF01118.24 AII58626.1 - 1.5e-26 93.2 0.0 2.5e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 AII58626.1 - 6.1e-14 52.5 0.0 9.7e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Na_H_Exchanger PF00999.21 AII58627.1 - 6.4e-69 232.6 59.1 9.4e-69 232.0 59.1 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 AII58627.1 - 3.6e-22 78.8 0.0 5.6e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain Lactamase_B_2 PF12706.7 AII58628.1 - 1.4e-24 86.7 0.0 1.7e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 AII58628.1 - 5.4e-10 39.4 0.0 8.7e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 AII58628.1 - 8.6e-10 38.9 0.2 2.5e-09 37.4 0.2 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Radical_SAM PF04055.21 AII58629.1 - 1.8e-14 54.5 0.0 2.9e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer2 PF00111.27 AII58629.1 - 0.37 10.8 3.1 4.3 7.4 0.6 2.6 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain DNA_topoisoIV PF00521.20 AII58630.1 - 2.7e-162 540.5 0.0 3.5e-162 540.2 0.0 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 AII58630.1 - 4.5e-53 176.5 14.0 2.2e-11 43.1 0.1 6.9 7 0 0 7 7 7 6 DNA gyrase C-terminal domain, beta-propeller IKI3 PF04762.12 AII58630.1 - 0.0022 16.1 1.8 0.0067 14.5 0.4 2.0 1 1 0 2 2 2 1 IKI3 family Sarcoglycan_1 PF04790.13 AII58630.1 - 0.064 12.6 0.1 0.14 11.5 0.1 1.5 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein TPR_1 PF00515.28 AII58631.1 - 1.3e-08 34.3 0.1 2.8e-06 26.9 0.3 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 AII58631.1 - 2e-08 33.7 0.2 1.9e-05 24.4 0.6 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 AII58631.1 - 3.9e-07 30.6 0.1 6.4e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 AII58631.1 - 2.3e-06 27.2 0.8 0.036 13.7 0.0 2.3 2 0 0 2 2 2 2 TPR repeat TPR_19 PF14559.6 AII58631.1 - 1.4e-05 25.5 0.1 2.7e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 AII58631.1 - 0.00018 21.9 0.2 1.3 9.9 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 AII58631.1 - 0.00051 20.3 0.1 0.0011 19.3 0.1 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 AII58631.1 - 0.00068 19.5 0.1 0.25 11.5 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 AII58631.1 - 0.0048 17.2 0.2 0.032 14.6 0.0 2.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 AII58631.1 - 0.012 16.4 0.2 1.4 9.9 0.3 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat RIG-I_C PF18119.1 AII58631.1 - 0.026 14.5 0.1 0.054 13.5 0.1 1.5 1 0 0 1 1 1 0 RIG-I receptor C-terminal domain PrcB_C PF14343.6 AII58631.1 - 0.04 14.1 0.2 3.2 7.9 0.1 2.4 2 0 0 2 2 2 0 PrcB C-terminal TPR_8 PF13181.6 AII58631.1 - 0.055 13.7 0.1 0.16 12.3 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 AII58631.1 - 0.068 13.4 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 AII58631.1 - 0.082 13.3 0.6 0.15 12.5 0.6 1.3 1 0 0 1 1 1 0 Bacterial transcriptional activator domain NifU PF01106.17 AII58632.1 - 7.3e-31 106.1 1.7 8.1e-31 106.0 1.7 1.0 1 0 0 1 1 1 1 NifU-like domain FeS_assembly_P PF01883.19 AII58632.1 - 0.00065 19.8 0.6 0.0013 18.9 0.6 1.5 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein AA_kinase PF00696.28 AII58633.1 - 4.4e-55 186.9 1.9 4.4e-55 186.9 1.9 1.4 2 0 0 2 2 2 1 Amino acid kinase family ACT PF01842.25 AII58633.1 - 1e-21 76.4 0.7 1.1e-11 44.2 0.1 3.1 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.6 AII58633.1 - 5e-21 74.3 2.8 8.1e-15 54.4 0.1 3.1 3 0 0 3 3 3 2 ACT domain ACT_6 PF13740.6 AII58633.1 - 0.0009 19.2 0.1 0.27 11.2 0.0 3.0 3 0 0 3 3 3 1 ACT domain DUF169 PF02596.15 AII58633.1 - 0.14 12.1 0.0 0.43 10.5 0.0 1.8 1 1 1 2 2 2 0 Uncharacterised ArCR, COG2043 DUF2615 PF11027.8 AII58634.1 - 0.039 14.1 0.0 0.046 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) Synaptobrevin PF00957.21 AII58634.1 - 0.12 12.2 1.1 0.15 11.8 1.1 1.1 1 0 0 1 1 1 0 Synaptobrevin FeoB_associated PF12669.7 AII58634.1 - 1 9.9 7.3 0.68 10.4 3.3 2.0 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein PhosphMutase PF10143.9 AII58635.1 - 1.5e-52 177.9 0.0 2e-52 177.5 0.0 1.2 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.18 AII58635.1 - 4.7e-24 85.1 0.0 6.2e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Metalloenzyme superfamily MazG PF03819.17 AII58636.1 - 2.7e-29 101.2 0.4 9.4e-23 80.2 0.1 2.4 2 0 0 2 2 2 2 MazG nucleotide pyrophosphohydrolase domain PRA-PH PF01503.17 AII58636.1 - 4.5e-06 27.0 1.2 0.05 14.1 0.0 2.9 3 0 0 3 3 3 2 Phosphoribosyl-ATP pyrophosphohydrolase DUF550 PF04447.12 AII58636.1 - 0.028 14.5 0.0 0.071 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF550) Urm1 PF09138.11 AII58636.1 - 0.16 12.3 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 Urm1 (Ubiquitin related modifier) Zn_peptidase_2 PF04298.12 AII58637.1 - 3.7e-83 278.2 1.0 4.2e-83 278.0 1.0 1.0 1 0 0 1 1 1 1 Putative neutral zinc metallopeptidase ApoL PF05461.11 AII58637.1 - 0.13 11.6 1.4 0.19 11.1 1.4 1.2 1 0 0 1 1 1 0 Apolipoprotein L Ribosomal_S20p PF01649.18 AII58638.1 - 4.5e-22 78.5 11.6 5e-22 78.3 11.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S20 DUF2680 PF10925.8 AII58638.1 - 0.0087 16.0 0.1 0.59 10.2 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2680) LexA_DNA_bind PF01726.16 AII58639.1 - 1.4e-14 53.6 0.0 3.5e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 LexA DNA binding domain Peptidase_S24 PF00717.23 AII58639.1 - 1.1e-11 44.5 0.1 1.8e-11 43.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like HTH_27 PF13463.6 AII58639.1 - 0.00073 20.0 0.0 0.0021 18.5 0.0 1.9 2 0 0 2 2 2 1 Winged helix DNA-binding domain MarR_2 PF12802.7 AII58639.1 - 0.0044 16.9 0.0 0.0083 16.0 0.0 1.4 1 0 0 1 1 1 1 MarR family Aldolase_II PF00596.21 AII58640.1 - 7.3e-32 110.8 0.0 9.1e-32 110.5 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain FKBP_N_2 PF18023.1 AII58640.1 - 0.21 11.7 0.0 0.33 11.1 0.0 1.2 1 0 0 1 1 1 0 BDBT FKBP like N-terminal Formyl_trans_N PF00551.19 AII58641.1 - 8.6e-37 126.6 0.0 1.1e-36 126.3 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 AII58641.1 - 5.7e-22 77.8 0.0 8.8e-22 77.2 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain DUF3800 PF12686.7 AII58642.1 - 1.2e-06 29.2 9.9 1.2e-06 29.2 9.9 1.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3800) Skp1 PF01466.19 AII58645.1 - 0.049 13.8 0.5 1.6 8.9 0.1 2.2 2 0 0 2 2 2 0 Skp1 family, dimerisation domain DUF5596 PF18082.1 AII58645.1 - 0.066 13.1 0.0 0.17 11.7 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5596) DUF2070 PF09843.9 AII58646.1 - 3.7 5.7 7.3 3.7 5.7 7.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Resolvase PF00239.21 AII58647.1 - 4.4e-33 114.5 0.7 1.3e-32 112.9 0.0 2.1 2 1 0 2 2 2 1 Resolvase, N terminal domain Recombinase PF07508.13 AII58647.1 - 4.1e-20 72.1 2.0 1e-19 70.8 0.2 2.2 2 0 0 2 2 2 1 Recombinase Zn_ribbon_recom PF13408.6 AII58647.1 - 3.7e-14 53.0 1.9 8e-14 51.9 1.9 1.6 1 0 0 1 1 1 1 Recombinase zinc beta ribbon domain SPOB_ab PF14682.6 AII58647.1 - 0.073 13.1 0.2 0.16 12.1 0.2 1.5 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal Spc7 PF08317.11 AII58647.1 - 0.12 11.3 10.1 0.22 10.4 10.1 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 AII58647.1 - 0.25 12.0 5.7 0.67 10.6 5.7 1.7 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Exonuc_VII_L PF02601.15 AII58647.1 - 0.27 10.8 4.8 0.42 10.1 4.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit ABC_tran_CTD PF16326.5 AII58647.1 - 0.4 11.0 7.2 0.75 10.1 3.1 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain YkyA PF10368.9 AII58647.1 - 0.72 9.5 7.1 1.2 8.7 6.6 1.6 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein CREPT PF16566.5 AII58647.1 - 1.7 8.8 8.2 0.44 10.7 4.8 1.7 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Trans_reg_C PF00486.28 AII58648.1 - 7.3e-13 48.4 0.5 2.1e-12 46.9 0.1 1.9 2 1 1 3 3 3 1 Transcriptional regulatory protein, C terminal HATPase_c PF02518.26 AII58648.1 - 2.4e-06 28.0 0.3 5.2e-06 26.9 0.3 1.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cdc13_OB4_dimer PF18233.1 AII58648.1 - 0.017 15.2 0.1 0.029 14.5 0.1 1.3 1 0 0 1 1 1 0 Cdc13 OB4 dimerization domain Init_tRNA_PT PF04179.12 AII58648.1 - 0.15 12.3 0.3 1.7 9.0 0.3 2.1 1 1 0 1 1 1 0 Rit1 DUSP-like domain MarR_2 PF12802.7 AII58649.1 - 1.3e-06 28.2 0.0 2.2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 MarR family MarR PF01047.22 AII58649.1 - 0.00015 21.6 0.0 0.00034 20.5 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_34 PF13601.6 AII58649.1 - 0.0004 20.5 0.2 0.00092 19.3 0.0 1.7 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_27 PF13463.6 AII58649.1 - 0.00047 20.6 0.0 0.00081 19.8 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain Fe_dep_repress PF01325.19 AII58649.1 - 0.02 15.1 0.0 0.044 14.0 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain DUF2695 PF10905.8 AII58650.1 - 0.085 13.1 0.3 1.2 9.4 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2695) zf-TFIIIC PF12660.7 AII58650.1 - 0.1 12.6 0.3 0.22 11.5 0.1 1.6 1 1 1 2 2 2 0 Putative zinc-finger of transcription factor IIIC complex AP1AR PF15745.5 AII58650.1 - 0.53 9.9 3.4 0.73 9.4 3.4 1.1 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein AAA PF00004.29 AII58652.1 - 5.8e-05 23.5 0.0 7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zot PF05707.12 AII58652.1 - 0.0021 17.7 0.2 0.013 15.1 0.1 2.3 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_14 PF13173.6 AII58652.1 - 0.0073 16.3 0.0 0.0099 15.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain Glyco_hydro_97 PF10566.9 AII58652.1 - 0.024 13.9 0.0 0.029 13.6 0.0 1.1 1 0 0 1 1 1 0 Glycoside hydrolase 97 ITAM_Cys-rich PF10538.9 AII58654.1 - 0.047 13.5 0.0 0.09 12.6 0.0 1.5 1 0 0 1 1 1 0 Immunoreceptor tyrosine-based activation motif DUF538 PF04398.12 AII58654.1 - 0.093 13.2 0.1 0.27 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF538 YrhC PF14143.6 AII58655.1 - 1.1 9.3 8.4 0.56 10.3 0.8 2.1 1 1 1 2 2 2 0 YrhC-like protein zf-Paramyx-P PF13008.7 AII58657.1 - 0.022 14.2 0.0 0.044 13.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding domain of Paramyxoviridae V protein SKN1 PF03935.15 AII58658.1 - 0.15 10.4 0.1 0.16 10.3 0.1 1.0 1 0 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) Peptidase_S24 PF00717.23 AII58659.1 - 1.3e-06 28.3 0.1 2.8e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 Peptidase S24-like DUF5389 PF17364.2 AII58660.1 - 0.045 13.8 0.3 0.058 13.4 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5389) Glucokinase PF02685.16 AII58661.1 - 0.021 13.8 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 Glucokinase HTH_3 PF01381.22 AII58664.1 - 1.5e-09 37.8 0.0 1.9e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 AII58664.1 - 3.9e-07 30.0 0.0 5e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 AII58664.1 - 2.6e-06 27.7 0.0 3.5e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 AII58664.1 - 1.5e-05 25.3 0.0 2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain CENP-B_N PF04218.13 AII58664.1 - 0.018 14.6 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_Crp_2 PF13545.6 AII58664.1 - 0.1 12.6 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HD_3 PF13023.6 AII58667.1 - 0.11 12.4 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 HD domain Laminin_I PF06008.14 AII58668.1 - 0.056 13.1 1.7 0.066 12.9 1.7 1.1 1 0 0 1 1 1 0 Laminin Domain I Porin_5 PF16930.5 AII58668.1 - 0.069 11.6 0.1 0.074 11.5 0.1 1.0 1 0 0 1 1 1 0 Putative porin UvrD-helicase PF00580.21 AII58671.1 - 2.3e-42 145.6 0.0 4.1e-23 82.4 0.0 2.2 1 1 1 2 2 2 2 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 AII58671.1 - 2e-25 89.8 0.0 3.7e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain UvrD_C PF13361.6 AII58671.1 - 4e-25 88.9 0.0 6.7e-20 71.8 0.0 2.1 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 AII58671.1 - 5.4e-08 32.6 0.1 2.2e-07 30.6 0.1 2.0 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 AII58671.1 - 2.7e-06 27.3 0.0 0.27 11.0 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 AII58671.1 - 6.3e-05 22.8 0.0 0.086 12.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 AII58671.1 - 0.045 14.0 0.6 25 5.1 0.1 3.2 3 1 1 4 4 4 0 AAA domain AAA_12 PF13087.6 AII58671.1 - 0.054 13.1 0.0 0.92 9.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.6 AII58671.1 - 0.26 11.1 0.0 0.44 10.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Iron_traffic PF04362.14 AII58673.1 - 0.053 13.2 0.5 0.64 9.7 0.1 2.3 2 0 0 2 2 2 0 Bacterial Fe(2+) trafficking DUF2795 PF11387.8 AII58674.1 - 4.3e-07 30.0 0.0 5.7e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2795) SLAC1 PF03595.17 AII58675.1 - 0.019 14.3 7.6 0.023 14.0 7.6 1.1 1 0 0 1 1 1 0 Voltage-dependent anion channel SAUGI PF06106.11 AII58675.1 - 0.15 12.6 4.2 0.099 13.2 2.1 1.8 2 0 0 2 2 2 0 S. aureus uracil DNA glycosylase inhibitor DUF2585 PF10755.9 AII58675.1 - 3.7 7.3 9.5 0.4 10.4 2.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2585) Ycf70 PF17382.2 AII58675.1 - 9.1 6.8 9.4 0.55 10.7 0.2 2.9 1 1 1 3 3 3 0 Uncharacterized Ycf70-like DUF1206 PF06724.11 AII58676.1 - 0.098 12.7 3.8 3.8 7.7 3.8 2.0 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1206) SKG6 PF08693.10 AII58676.1 - 0.13 11.7 1.2 0.13 11.7 1.2 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain YajC PF02699.15 AII58678.1 - 0.0059 16.5 0.5 0.0059 16.5 0.5 1.6 2 0 0 2 2 2 1 Preprotein translocase subunit 7TM_GPCR_Srab PF10292.9 AII58678.1 - 0.0083 15.1 1.0 0.01 14.8 1.0 1.0 1 0 0 1 1 1 1 Serpentine type 7TM GPCR receptor class ab chemoreceptor Peptidase_S49_N PF08496.10 AII58678.1 - 0.016 15.3 0.9 0.016 15.3 0.9 1.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal GRP PF07172.11 AII58678.1 - 0.018 15.7 0.0 0.028 15.1 0.0 1.4 1 0 0 1 1 1 0 Glycine rich protein family COX16 PF14138.6 AII58678.1 - 0.056 14.0 0.5 0.1 13.2 0.5 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 PTR2 PF00854.21 AII58678.1 - 0.066 12.0 0.8 0.076 11.8 0.8 1.1 1 0 0 1 1 1 0 POT family MpPF26 PF07666.11 AII58678.1 - 0.11 12.7 6.1 0.13 12.4 6.1 1.2 1 0 0 1 1 1 0 M penetrans paralogue family 26 DUF4519 PF15012.6 AII58678.1 - 3.1 8.1 6.4 26 5.1 1.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) PSRP-3_Ycf65 PF04839.13 AII58679.1 - 0.0019 18.4 0.3 0.0027 17.9 0.3 1.3 1 0 0 1 1 1 1 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) ApoO PF09769.9 AII58679.1 - 0.012 15.6 0.0 0.014 15.4 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein O Phage_DNA_bind PF02303.17 AII58682.1 - 0.16 12.3 0.0 0.43 10.9 0.0 1.7 2 0 0 2 2 2 0 Helix-destabilising protein Dehalogenase PF13486.6 AII58683.1 - 9.9e-70 235.2 0.0 1.4e-69 234.7 0.0 1.2 1 0 0 1 1 1 1 Reductive dehalogenase subunit Fer4_16 PF13484.6 AII58683.1 - 7.1e-12 46.1 10.9 1.6e-11 44.9 10.9 1.7 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 AII58683.1 - 4.4e-08 33.6 11.5 8.6e-08 32.7 11.5 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AII58683.1 - 4e-05 23.7 5.6 0.031 14.4 2.9 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 AII58683.1 - 0.00015 21.7 10.6 0.02 15.0 3.0 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 AII58683.1 - 0.00017 22.0 3.5 0.6 10.6 0.0 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 AII58683.1 - 0.00062 19.5 9.9 0.0042 16.9 0.8 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain TAT_signal PF10518.9 AII58683.1 - 0.0019 18.0 0.7 0.0019 18.0 0.7 2.1 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence Fer4_10 PF13237.6 AII58683.1 - 0.014 15.5 14.1 0.14 12.3 15.1 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 AII58683.1 - 0.042 14.0 11.6 3.1 8.0 11.6 2.3 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 AII58683.1 - 0.72 10.4 13.8 1 9.9 3.9 2.5 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 AII58683.1 - 0.8 9.9 10.7 6.7 7.0 0.5 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 AII58683.1 - 2.6 8.8 11.2 9.3 7.0 2.7 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 AII58683.1 - 8.2 7.6 17.3 4 8.6 6.1 2.7 2 1 0 2 2 2 0 4Fe-4S binding domain PAS_8 PF13188.7 AII58684.1 - 1.8e-08 34.2 0.0 2.7e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AII58684.1 - 0.00021 21.3 0.0 0.00039 20.4 0.0 1.5 1 1 0 1 1 1 1 PAS fold PAS_9 PF13426.7 AII58684.1 - 0.00025 21.2 0.0 0.00041 20.6 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 AII58684.1 - 0.16 12.3 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 PAS fold zf-H2C2_2 PF13465.6 AII58687.1 - 0.00054 20.3 5.1 0.022 15.2 0.3 2.5 2 1 0 2 2 2 2 Zinc-finger double domain Zn-ribbon_8 PF09723.10 AII58687.1 - 0.0068 16.5 3.1 0.34 11.1 0.1 2.3 2 0 0 2 2 2 2 Zinc ribbon domain Lar_restr_allev PF14354.6 AII58687.1 - 0.016 15.6 0.9 0.02 15.3 0.9 1.2 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-ZPR1 PF03367.13 AII58687.1 - 0.05 13.5 1.8 0.086 12.7 1.8 1.5 1 1 0 1 1 1 0 ZPR1 zinc-finger domain Ribosomal_L37e PF01907.19 AII58687.1 - 0.052 13.7 4.2 2.6 8.3 0.8 2.2 2 0 0 2 2 2 0 Ribosomal protein L37e zinc_ribbon_5 PF13719.6 AII58687.1 - 0.12 12.1 0.4 0.12 12.1 0.4 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 AII58687.1 - 0.14 12.1 5.7 0.4 10.7 5.8 1.7 1 1 1 2 2 2 0 Transposase zinc-ribbon domain TFIIS_C PF01096.18 AII58687.1 - 8.1 6.4 10.9 1.3e+02 2.5 10.9 2.1 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS) Fer4_5 PF12801.7 AII58693.1 - 2.3e-16 59.4 15.0 5.1e-13 48.8 1.3 3.9 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4 PF00037.27 AII58693.1 - 4e-06 26.4 14.1 3.6e-05 23.4 1.0 4.1 4 0 0 4 4 4 1 4Fe-4S binding domain Fer4_16 PF13484.6 AII58693.1 - 1.6e-05 25.7 5.2 0.0011 19.8 0.3 3.6 4 0 0 4 4 4 1 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 AII58693.1 - 3.6e-05 23.8 10.7 3.6e-05 23.8 10.7 2.2 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 AII58693.1 - 0.00027 21.5 9.7 0.00027 21.5 9.7 2.7 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_18 PF13746.6 AII58693.1 - 0.001 19.2 1.5 0.12 12.6 1.1 2.7 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AII58693.1 - 0.0023 18.0 2.0 0.0023 18.0 2.0 3.1 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 AII58693.1 - 0.0092 16.1 9.6 0.048 13.8 8.6 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain E1-E2_ATPase PF00122.20 AII58693.1 - 0.14 11.7 2.1 0.4 10.2 0.1 2.4 2 0 0 2 2 2 0 E1-E2 ATPase Fer4_6 PF12837.7 AII58693.1 - 0.26 11.5 17.0 1.2 9.3 3.3 3.4 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_15 PF13459.6 AII58693.1 - 5.6 7.8 6.6 1.7 9.5 0.6 2.4 1 1 1 2 2 2 0 4Fe-4S single cluster domain HD_5 PF13487.6 AII58695.1 - 1.9e-07 31.2 0.0 3.1e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 HD domain HD PF01966.22 AII58695.1 - 0.012 15.8 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 HD domain K-box PF01486.17 AII58696.1 - 0.0024 18.0 0.9 0.0036 17.4 0.9 1.2 1 0 0 1 1 1 1 K-box region zf-C2HC_2 PF13913.6 AII58696.1 - 0.025 14.5 1.8 0.025 14.5 1.8 3.2 4 0 0 4 4 4 0 zinc-finger of a C2HC-type Rad50_zn_hook PF04423.14 AII58696.1 - 0.098 12.5 0.1 0.098 12.5 0.1 3.0 3 1 1 4 4 4 0 Rad50 zinc hook motif MRP-S28 PF10213.9 AII58696.1 - 0.14 12.5 0.1 0.19 12.1 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit protein Prok-RING_1 PF14446.6 AII58696.1 - 0.27 11.2 2.4 0.58 10.1 2.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-C2H2 PF00096.26 AII58696.1 - 0.69 10.5 2.3 2.6 8.7 0.1 2.5 1 1 1 2 2 2 0 Zinc finger, C2H2 type UPF0547 PF10571.9 AII58696.1 - 1 9.5 6.5 4.6 7.4 6.5 2.1 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 Vps36-NZF-N PF16988.5 AII58696.1 - 3.7 7.0 8.2 0.19 11.1 1.0 2.5 2 1 1 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-C2H2_4 PF13894.6 AII58696.1 - 4.6 8.3 6.7 17 6.6 0.1 3.3 2 1 1 3 3 3 0 C2H2-type zinc finger DUF4101 PF13355.6 AII58697.1 - 0.25 11.8 5.1 1.7 9.1 4.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4101) DivIVA PF05103.13 AII58697.1 - 0.6 10.2 14.4 0.39 10.8 4.3 2.2 1 1 1 2 2 2 0 DivIVA protein TPR_1 PF00515.28 AII58698.1 - 1.1e-14 53.5 8.5 1.9e-10 40.1 0.6 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 AII58698.1 - 7e-13 47.6 3.1 1.4e-07 31.1 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 AII58698.1 - 3e-09 36.4 1.4 0.00023 21.1 0.4 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 AII58698.1 - 4.1e-09 36.2 3.8 8.6e-05 22.7 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 AII58698.1 - 3.2e-08 33.1 2.5 3.5e-06 26.6 0.3 2.9 1 1 1 2 2 2 2 TPR repeat TPR_12 PF13424.6 AII58698.1 - 1.8e-05 24.9 0.0 0.33 11.3 0.1 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 AII58698.1 - 0.00026 21.6 0.0 0.0011 19.6 0.0 1.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 AII58698.1 - 0.00053 20.4 0.0 0.012 16.1 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 AII58698.1 - 0.03 14.6 1.2 0.043 14.0 1.1 1.4 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 AII58698.1 - 0.056 13.6 0.0 0.088 13.0 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat MIT PF04212.18 AII58698.1 - 0.07 13.2 0.5 7.4 6.7 0.0 2.5 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.6 AII58698.1 - 0.14 13.0 0.0 2.5 9.1 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat InaF-motif PF15018.6 AII58699.1 - 0.036 13.9 4.3 0.054 13.4 4.3 1.5 1 1 0 1 1 1 0 TRP-interacting helix TssO PF17561.2 AII58699.1 - 0.97 9.5 2.7 1.1 9.4 2.7 1.0 1 0 0 1 1 1 0 Type VI secretion system, TssO 60KD_IMP PF02096.20 AII58701.1 - 2.7e-51 173.8 10.4 3.4e-51 173.4 10.4 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein EMC3_TMCO1 PF01956.16 AII58701.1 - 0.014 15.1 12.8 0.031 14.0 0.1 2.5 1 1 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like SCIMP PF15050.6 AII58701.1 - 0.044 14.2 0.2 0.12 12.8 0.2 1.8 1 0 0 1 1 1 0 SCIMP protein Tim17 PF02466.19 AII58702.1 - 0.024 15.0 1.9 0.71 10.3 0.2 2.3 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Phage_Mu_F PF04233.14 AII58703.1 - 0.00029 21.6 1.0 0.00045 20.9 1.0 1.6 1 1 0 1 1 1 1 Phage Mu protein F like protein Transgly PF00912.22 AII58703.1 - 0.0009 18.7 0.6 0.0011 18.4 0.6 1.2 1 0 0 1 1 1 1 Transglycosylase zf-C2HC5 PF06221.13 AII58703.1 - 0.018 15.0 0.4 0.018 15.0 0.4 2.1 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type DZR PF12773.7 AII58703.1 - 0.11 12.6 0.9 0.11 12.6 0.9 2.6 2 1 0 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.6 AII58703.1 - 0.28 10.7 11.7 7.4 6.1 6.9 3.2 2 1 0 2 2 2 0 zinc-ribbon domain Anti-TRAP PF15777.5 AII58703.1 - 0.44 10.5 3.0 1.9 8.5 1.1 2.7 2 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein zinc-ribbons_6 PF07191.12 AII58703.1 - 0.46 10.5 5.6 0.49 10.4 0.5 2.6 2 0 0 2 2 2 0 zinc-ribbons Ogr_Delta PF04606.12 AII58703.1 - 0.57 10.2 4.4 1.9 8.5 0.0 3.0 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger Auto_anti-p27 PF06677.12 AII58703.1 - 2.4 8.4 7.6 1.2 9.4 2.4 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) HTH_19 PF12844.7 AII58704.1 - 0.061 13.3 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Phage_CII PF05269.11 AII58704.1 - 0.07 13.4 0.0 0.09 13.0 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage CII protein zf-FCS PF06467.14 AII58705.1 - 0.023 14.6 1.0 0.025 14.5 0.1 1.5 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DUF2870 PF11069.8 AII58706.1 - 0.003 17.9 0.2 0.003 17.9 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) DUF4373 PF14297.6 AII58709.1 - 4.3e-15 56.3 0.2 9.7e-15 55.1 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4373) DnaB_2 PF07261.11 AII58709.1 - 9.9e-13 47.6 0.2 2.3e-12 46.5 0.2 1.6 1 0 0 1 1 1 1 Replication initiation and membrane attachment HTH_17 PF12728.7 AII58711.1 - 0.00021 21.4 0.0 0.00059 20.0 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 AII58711.1 - 0.01 16.1 0.0 2.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Transposase HNH PF01844.23 AII58713.1 - 0.058 13.6 11.4 0.13 12.5 11.4 1.7 1 1 0 1 1 1 0 HNH endonuclease HTH_3 PF01381.22 AII58715.1 - 1.1e-09 38.2 0.0 1.5e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_26 PF13443.6 AII58715.1 - 2.3e-05 24.7 0.0 3.3e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_31 PF13560.6 AII58715.1 - 0.0063 16.8 0.0 0.0084 16.4 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 AII58715.1 - 0.013 15.4 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 AII58715.1 - 0.054 13.1 0.0 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding DUF2158 PF09926.9 AII58718.1 - 0.067 12.9 0.4 0.1 12.3 0.4 1.3 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2158) DUF2292 PF10055.9 AII58720.1 - 0.017 14.8 0.4 0.026 14.1 0.4 1.4 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2292) DUF3137 PF11335.8 AII58720.1 - 0.019 14.9 0.1 0.019 14.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3137) IBR PF01485.21 AII58721.1 - 0.011 15.9 0.3 0.015 15.5 0.3 1.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C2H2_4 PF13894.6 AII58721.1 - 0.075 13.9 1.2 3.8 8.6 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Dof PF02701.15 AII58721.1 - 0.31 11.2 3.5 0.49 10.6 3.5 1.3 1 1 0 1 1 1 0 Dof domain, zinc finger Metallophos PF00149.28 AII58724.1 - 0.0088 16.6 0.3 0.062 13.8 0.3 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase 3D PF06725.11 AII58724.1 - 0.09 13.0 0.1 0.51 10.6 0.0 2.1 2 0 0 2 2 2 0 3D domain PQ-loop PF04193.14 AII58725.1 - 1.4e-09 37.5 2.0 1.4e-09 37.5 2.0 1.7 1 1 1 2 2 2 1 PQ loop repeat MtN3_slv PF03083.16 AII58725.1 - 2.2e-05 24.4 3.4 2.6e-05 24.2 3.4 1.1 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange SLATT_5 PF18160.1 AII58727.1 - 0.0017 17.7 0.6 0.3 10.4 0.0 2.2 2 0 0 2 2 2 2 SMODS and SLOG-associating 2TM effector domain family 5 DUF2637 PF10935.8 AII58727.1 - 0.13 12.2 0.1 0.13 12.2 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2637) DUF4064 PF13273.6 AII58727.1 - 0.68 10.2 6.5 0.6 10.4 4.4 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) HTH_Crp_2 PF13545.6 AII58730.1 - 0.075 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_23 PF13384.6 AII58730.1 - 0.11 12.4 0.0 0.38 10.6 0.0 1.8 2 0 0 2 2 2 0 Homeodomain-like domain Phage_portal PF04860.12 AII58731.1 - 5.6e-64 216.3 0.0 9.3e-64 215.6 0.0 1.3 1 0 0 1 1 1 1 Phage portal protein Phage_Mu_F PF04233.14 AII58731.1 - 2.9e-12 47.3 0.0 7.8e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 Phage Mu protein F like protein Phage_capsid PF05065.13 AII58732.1 - 2.3e-49 168.2 0.4 3.3e-49 167.7 0.1 1.4 2 0 0 2 2 2 1 Phage capsid family Rubella_Capsid PF05750.11 AII58735.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Rubella capsid protein Fmp27 PF10344.9 AII58735.1 - 0.15 10.2 0.0 0.17 10.0 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 Nbl1_Borealin_N PF10444.9 AII58735.1 - 0.16 11.6 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal Phage_spike PF18715.1 AII58736.1 - 0.041 14.0 0.2 0.041 14.0 0.2 3.4 5 0 0 5 5 5 0 Phage spike trimer GP38 PF05268.11 AII58736.1 - 4.3 6.9 8.9 29 4.2 5.0 2.2 2 0 0 2 2 2 0 Phage tail fibre adhesin Gp38 BppU_N PF10651.9 AII58738.1 - 2.6e-09 36.9 0.0 3e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 BppU N-terminal domain Invasin_D3 PF09134.10 AII58738.1 - 0.00053 20.3 3.3 0.0012 19.1 3.3 1.7 1 1 0 1 1 1 1 Invasin, domain 3 Big_3_2 PF12245.8 AII58738.1 - 0.0012 19.1 0.0 0.0035 17.6 0.0 1.7 2 0 0 2 2 2 1 Bacterial Ig-like domain Phage_connect_1 PF05135.13 AII58739.1 - 5.4e-06 26.8 0.0 1.2e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Phage gp6-like head-tail connector protein DUF1258 PF06869.12 AII58740.1 - 0.039 13.4 0.1 0.044 13.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) Phage_tail_2 PF06199.11 AII58741.1 - 0.026 14.6 0.6 0.68 10.0 0.6 2.0 1 1 0 1 1 1 0 Phage tail tube protein MCPsignal PF00015.21 AII58744.1 - 0.0067 16.3 2.9 0.73 9.6 0.3 2.6 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HTH_Tnp_1 PF01527.20 AII58744.1 - 0.035 14.4 0.0 0.09 13.1 0.0 1.6 1 0 0 1 1 1 0 Transposase Promethin PF16015.5 AII58744.1 - 0.057 13.4 3.3 0.11 12.4 3.3 1.4 1 0 0 1 1 1 0 Promethin DUF726 PF05277.12 AII58744.1 - 5.8 5.7 10.8 0.91 8.4 2.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF726) ToxB_N PF18224.1 AII58746.1 - 0.15 12.0 0.2 6.1 6.9 0.0 2.4 2 0 0 2 2 2 0 ToxB N-terminal domain Peptidase_M50B PF13398.6 AII58747.1 - 0.0065 16.1 0.4 0.0066 16.1 0.4 1.0 1 0 0 1 1 1 1 Peptidase M50B-like XhlA PF10779.9 AII58749.1 - 0.0057 16.8 3.3 0.0087 16.2 2.7 1.7 1 1 0 1 1 1 1 Haemolysin XhlA Alanine_zipper PF11839.8 AII58749.1 - 0.01 16.2 2.9 0.01 16.2 2.9 1.6 1 1 1 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein DUF2514 PF10721.9 AII58749.1 - 0.021 14.9 0.3 0.023 14.8 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) T3SSipB PF16535.5 AII58749.1 - 0.028 14.9 1.7 0.033 14.7 1.7 1.1 1 0 0 1 1 1 0 Type III cell invasion protein SipB DUF2076 PF09849.9 AII58749.1 - 0.055 13.5 0.2 0.4 10.7 0.0 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Med4 PF10018.9 AII58749.1 - 0.057 13.1 3.1 0.067 12.9 3.1 1.0 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Lectin_C_term PF18022.1 AII58750.1 - 9e-07 29.3 0.0 2.1e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin C-terminal domain Agglutinin_C PF18021.1 AII58750.1 - 1.1e-06 29.0 0.0 6e-06 26.7 0.0 1.9 1 1 0 1 1 1 1 Agglutinin C-terminal Acetyltransf_10 PF13673.7 AII58751.1 - 1e-08 35.1 0.0 2.6e-08 33.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 AII58751.1 - 2e-06 28.1 0.0 2.8e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 AII58751.1 - 0.0027 17.9 0.0 0.003 17.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family YjcZ PF13990.6 AII58752.1 - 0.092 12.1 0.0 0.092 12.1 0.0 1.0 1 0 0 1 1 1 0 YjcZ-like protein Big_1 PF02369.16 AII58755.1 - 6.3e-45 151.0 115.9 1.9e-13 50.2 0.4 16.6 14 5 2 16 16 16 7 Bacterial Ig-like domain (group 1) Invasin_D3 PF09134.10 AII58755.1 - 5e-14 52.4 126.7 4.6e-06 26.8 2.0 13.3 12 2 1 14 14 13 8 Invasin, domain 3 Glyco_hydro2_C5 PF18565.1 AII58755.1 - 8.7e-10 38.4 8.4 0.49 10.3 0.1 9.4 10 1 0 10 10 10 3 Glycoside hydrolase family 2 C-terminal domain 5 CarboxypepD_reg PF13620.6 AII58755.1 - 4e-08 33.4 0.0 4e-08 33.4 0.0 11.1 10 1 1 11 11 11 3 Carboxypeptidase regulatory-like domain MG4 PF17789.1 AII58755.1 - 3.3e-05 23.9 23.7 0.36 11.0 0.1 8.6 9 0 0 9 9 9 2 Macroglobulin domain MG4 SdrD_B PF17210.3 AII58755.1 - 0.00018 21.7 0.1 0.00018 21.7 0.1 6.1 7 0 0 7 7 6 1 SdrD B-like domain bMG3 PF11974.8 AII58755.1 - 0.00025 21.0 0.1 0.03 14.3 0.0 3.8 3 0 0 3 3 3 1 Bacterial alpha-2-macroglobulin MG3 domain SpaA PF17802.1 AII58755.1 - 0.013 15.8 0.1 0.013 15.8 0.1 6.4 8 0 0 8 8 8 0 Prealbumin-like fold domain DUF2012 PF09430.10 AII58755.1 - 0.042 14.0 0.0 0.26 11.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2012) Ntox44 PF15607.6 AII58755.1 - 0.052 13.9 2.1 8.3 6.8 0.0 4.1 4 0 0 4 4 4 0 Bacterial toxin 44 CarbopepD_reg_2 PF13715.6 AII58755.1 - 0.089 12.8 0.0 0.089 12.8 0.0 6.1 7 0 0 7 7 7 0 CarboxypepD_reg-like domain DUF748 PF05359.11 AII58755.1 - 0.25 11.5 1.3 15 5.7 0.2 3.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF748) DUF824 PF05688.11 AII58755.1 - 0.81 9.6 13.7 19 5.2 0.0 7.2 7 1 1 8 8 8 0 Salmonella repeat of unknown function (DUF824) DUF2993 PF11209.8 AII58755.1 - 3.9 7.7 17.8 2.8 8.1 2.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2993) VASP_tetra PF08776.11 AII58759.1 - 0.051 13.1 0.5 0.051 13.1 0.5 1.8 2 0 0 2 2 2 0 VASP tetramerisation domain ParD PF09386.10 AII58760.1 - 1.3e-05 25.5 0.0 1.7e-05 25.1 0.0 1.3 1 1 0 1 1 1 1 Antitoxin ParD DUF202 PF02656.15 AII58762.1 - 0.028 14.9 1.1 0.035 14.6 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF202) HATPase_c PF02518.26 AII58765.1 - 6.7e-20 71.7 0.0 1.5e-19 70.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AII58765.1 - 1.4e-15 57.0 0.7 4.1e-15 55.6 0.1 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 AII58765.1 - 5e-05 23.2 0.0 0.00012 22.0 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 AII58765.1 - 0.00014 22.1 0.0 0.00063 20.0 0.0 2.2 1 1 0 1 1 1 1 PAS domain HATPase_c_5 PF14501.6 AII58765.1 - 0.0045 16.9 0.0 0.018 14.9 0.0 2.0 2 0 0 2 2 2 1 GHKL domain HATPase_c_3 PF13589.6 AII58765.1 - 0.041 13.7 0.0 0.087 12.6 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Mu-like_Pro PF10123.9 AII58765.1 - 0.1 12.2 0.1 0.36 10.3 0.1 1.7 2 0 0 2 2 2 0 Mu-like prophage I protein eIF_4G1 PF12152.8 AII58766.1 - 0.2 11.9 0.0 0.33 11.2 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4G1 LPD24 PF18839.1 AII58768.1 - 0.092 13.0 0.0 0.098 12.9 0.0 1.1 1 0 0 1 1 1 0 Large polyvalent protein associated domain 24 Myb_DNA-bind_6 PF13921.6 AII58770.1 - 0.08 13.2 0.1 0.43 10.9 0.0 2.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain Sigma70_r4_2 PF08281.12 AII58770.1 - 0.17 11.5 0.1 0.31 10.7 0.1 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Reg_prop PF07494.11 AII58772.1 - 7.9e-56 178.9 47.6 5.2e-05 23.0 0.1 14.7 14 0 0 14 14 14 13 Two component regulator propeller HATPase_c PF02518.26 AII58772.1 - 1.2e-22 80.5 0.7 4.7e-22 78.6 0.1 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SGL PF08450.12 AII58772.1 - 1.9e-14 53.9 4.7 0.022 14.3 0.0 6.9 1 1 5 6 6 6 5 SMP-30/Gluconolactonase/LRE-like region Y_Y_Y PF07495.13 AII58772.1 - 5.5e-12 45.5 0.4 1.5e-11 44.1 0.4 1.8 1 0 0 1 1 1 1 Y_Y_Y domain HisKA PF00512.25 AII58772.1 - 1.3e-06 28.3 0.6 3.4e-06 27.0 0.0 2.1 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain DUF5074 PF16819.5 AII58772.1 - 1.6e-06 28.1 5.1 3.4 7.7 0.0 6.9 5 2 1 6 6 6 2 Domain of unknown function (DUF5074) HATPase_c_5 PF14501.6 AII58772.1 - 5.1e-05 23.1 0.0 0.00023 21.0 0.0 2.2 1 0 0 1 1 1 1 GHKL domain NigD_N PF12667.7 AII58772.1 - 0.017 15.2 4.9 19 5.5 0.1 5.2 6 1 1 7 7 7 0 NigD-like N-terminal OB domain RSN1_TM PF13967.6 AII58772.1 - 0.021 14.6 1.6 0.29 10.9 0.1 2.8 2 0 0 2 2 2 0 Late exocytosis, associated with Golgi transport DUF5104 PF17117.5 AII58772.1 - 0.57 10.6 0.0 0.57 10.6 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF5104) Reg_prop PF07494.11 AII58773.1 - 2.6e-54 174.3 46.4 2.1e-05 24.2 0.5 14.1 14 0 0 14 14 14 12 Two component regulator propeller HATPase_c PF02518.26 AII58773.1 - 2.2e-19 70.0 0.1 4.3e-18 65.9 0.0 3.1 4 0 0 4 4 4 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SGL PF08450.12 AII58773.1 - 6.4e-08 32.5 2.5 0.022 14.4 0.5 5.1 2 1 1 4 4 4 2 SMP-30/Gluconolactonase/LRE-like region HisKA PF00512.25 AII58773.1 - 1.5e-06 28.2 0.4 9.9e-06 25.5 0.1 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Y_Y_Y PF07495.13 AII58773.1 - 2e-05 24.5 0.2 7.3e-05 22.6 0.2 2.0 1 0 0 1 1 1 1 Y_Y_Y domain DUF5074 PF16819.5 AII58773.1 - 3.8e-05 23.7 12.5 0.11 12.5 0.1 6.1 7 0 0 7 7 7 3 Domain of unknown function (DUF5074) TMC PF07810.13 AII58773.1 - 0.037 14.6 0.1 0.2 12.2 0.1 2.3 1 0 0 1 1 1 0 TMC domain Ntox33 PF15533.6 AII58773.1 - 0.21 12.1 3.6 10 6.7 0.0 4.6 4 1 1 5 5 5 0 Bacterial toxin 33 HATPase_c PF02518.26 AII58775.1 - 2.1e-26 92.6 0.0 4.1e-26 91.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AII58775.1 - 6.8e-11 42.1 0.8 7.6e-10 38.7 0.2 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 AII58775.1 - 1.1e-07 32.0 0.7 4.5e-07 30.1 0.0 2.3 3 0 0 3 3 3 1 PAS domain HATPase_c_2 PF13581.6 AII58775.1 - 0.0015 18.5 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain KH_9 PF17904.1 AII58775.1 - 0.0074 16.6 0.0 0.054 13.9 0.0 2.3 2 0 0 2 2 2 1 FMRP KH0 domain PAS_8 PF13188.7 AII58775.1 - 0.016 15.2 0.0 0.038 14.0 0.0 1.6 1 0 0 1 1 1 0 PAS domain HATPase_c_3 PF13589.6 AII58775.1 - 0.031 14.1 0.0 0.066 13.0 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 AII58775.1 - 0.034 14.4 0.0 0.12 12.7 0.0 1.9 1 1 0 1 1 1 0 PAS fold HATPase_c_5 PF14501.6 AII58775.1 - 0.056 13.4 0.3 0.21 11.5 0.0 2.1 2 0 0 2 2 1 0 GHKL domain PAS PF00989.25 AII58775.1 - 0.084 12.9 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 PAS fold NRBF2 PF08961.10 AII58775.1 - 0.11 12.1 1.0 0.88 9.1 0.1 2.3 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator YabA PF06156.13 AII58775.1 - 0.32 11.6 2.6 0.47 11.1 0.3 2.5 2 0 0 2 2 2 0 Initiation control protein YabA PikAIV_N PF18605.1 AII58775.1 - 2.2 8.0 5.8 0.68 9.6 2.8 1.8 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain TSC22 PF01166.18 AII58775.1 - 6 7.3 9.0 0.22 11.9 0.8 2.8 3 0 0 3 3 3 0 TSC-22/dip/bun family MarR_2 PF12802.7 AII58776.1 - 1.8e-06 27.7 0.7 3.3e-06 26.9 0.1 1.7 2 0 0 2 2 2 1 MarR family MarR PF01047.22 AII58776.1 - 2.1e-06 27.5 0.1 4.5e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 AII58776.1 - 0.00021 21.7 0.5 0.00044 20.7 0.1 1.7 2 0 0 2 2 2 1 Winged helix DNA-binding domain Penicillinase_R PF03965.16 AII58776.1 - 0.00095 19.5 1.0 0.039 14.3 0.1 2.2 2 0 0 2 2 2 1 Penicillinase repressor Fe_dep_repress PF01325.19 AII58776.1 - 0.0014 18.8 0.0 0.0036 17.5 0.0 1.8 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_IclR PF09339.10 AII58776.1 - 0.0032 17.2 0.7 0.0074 16.1 0.2 1.9 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_24 PF13412.6 AII58776.1 - 0.0096 15.5 0.6 0.038 13.6 0.1 2.2 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Tn7_Tnp_TnsA_C PF08721.11 AII58776.1 - 0.034 14.8 0.4 4.7 7.9 0.1 2.5 2 1 1 3 3 3 0 TnsA endonuclease C terminal TrmB PF01978.19 AII58776.1 - 0.059 13.3 2.3 0.062 13.2 0.1 2.1 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB HTH_47 PF16221.5 AII58776.1 - 0.11 12.1 0.1 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 winged helix-turn-helix Terminase_5 PF06056.12 AII58776.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Dehalogenase PF13486.6 AII58777.1 - 1e-57 195.7 0.3 1.2e-56 192.2 0.3 2.2 2 1 0 2 2 2 1 Reductive dehalogenase subunit Fer4_16 PF13484.6 AII58777.1 - 3.2e-10 40.8 6.0 7.2e-10 39.7 6.0 1.6 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4 PF00037.27 AII58777.1 - 0.00049 19.8 2.2 0.0014 18.4 2.2 1.8 1 0 0 1 1 1 1 4Fe-4S binding domain TAT_signal PF10518.9 AII58777.1 - 0.0011 18.7 1.2 0.0024 17.6 1.2 1.5 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence Fer4_10 PF13237.6 AII58777.1 - 0.011 15.8 0.5 0.011 15.8 0.5 2.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 AII58777.1 - 0.026 15.1 2.8 0.11 13.0 0.3 2.6 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 AII58777.1 - 0.029 15.0 7.4 0.085 13.5 7.4 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 AII58777.1 - 0.11 13.1 2.5 0.36 11.5 2.5 1.8 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_8 PF13183.6 AII58777.1 - 0.39 11.2 9.3 9.2 6.8 10.6 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 AII58777.1 - 0.39 10.9 9.1 0.26 11.5 3.0 2.3 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 AII58777.1 - 1.3 10.2 6.4 3.7 8.7 6.4 1.9 1 0 0 1 1 1 0 4Fe-4S binding domain HATPase_c PF02518.26 AII58778.1 - 1.6e-24 86.6 0.9 5e-24 85.0 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 AII58778.1 - 5.3e-08 33.0 0.1 2e-07 31.2 0.1 2.0 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 AII58778.1 - 0.00013 21.9 0.0 0.00033 20.6 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 AII58778.1 - 0.00046 20.2 0.1 0.0012 18.8 0.1 1.7 1 0 0 1 1 1 1 PAS fold HisKA PF00512.25 AII58778.1 - 0.00054 19.9 1.6 0.00069 19.6 0.1 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AII58778.1 - 0.026 14.4 0.1 0.026 14.4 0.1 2.4 3 0 0 3 3 3 0 GHKL domain CREPT PF16566.5 AII58778.1 - 0.065 13.4 0.9 0.12 12.6 0.9 1.5 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Sigma70_r4_2 PF08281.12 AII58780.1 - 0.16 11.6 0.1 0.32 10.7 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 MarR_2 PF12802.7 AII58781.1 - 0.00021 21.1 0.0 0.00036 20.4 0.0 1.3 1 0 0 1 1 1 1 MarR family PAX PF00292.18 AII58781.1 - 0.0026 17.7 0.0 0.027 14.4 0.0 2.1 2 0 0 2 2 2 1 'Paired box' domain MarR PF01047.22 AII58781.1 - 0.0033 17.3 0.0 0.0064 16.4 0.0 1.5 1 0 0 1 1 1 1 MarR family Fe_dep_repress PF01325.19 AII58781.1 - 0.039 14.1 0.0 0.081 13.1 0.0 1.5 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_34 PF13601.6 AII58781.1 - 0.041 14.1 0.0 0.094 12.9 0.0 1.6 2 0 0 2 2 2 0 Winged helix DNA-binding domain Dehalogenase PF13486.6 AII58783.1 - 2.4e-50 171.6 0.2 6.1e-50 170.2 0.2 1.6 1 1 0 1 1 1 1 Reductive dehalogenase subunit Fer4_16 PF13484.6 AII58783.1 - 5.9e-09 36.7 4.0 1.1e-08 35.8 4.0 1.5 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 AII58783.1 - 4.7e-06 27.1 4.0 1e-05 26.0 4.0 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 AII58783.1 - 9.1e-05 22.6 2.1 0.03 14.5 0.2 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 AII58783.1 - 0.00027 21.4 4.5 0.21 12.2 0.3 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 AII58783.1 - 0.0025 17.6 3.0 0.0025 17.6 3.0 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_10 PF13237.6 AII58783.1 - 0.0054 16.8 6.6 0.46 10.6 1.0 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 AII58783.1 - 0.022 15.2 3.6 2.3 8.7 0.1 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 AII58783.1 - 0.86 10.4 4.4 15 6.4 1.1 2.3 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_2 PF12797.7 AII58783.1 - 2 8.7 14.8 6.7 7.0 3.1 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_21 PF14697.6 AII58783.1 - 2.3 8.4 8.5 4.1 7.6 1.9 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain HATPase_c PF02518.26 AII58784.1 - 1.9e-27 96.0 0.1 6.3e-27 94.3 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 AII58784.1 - 2e-09 37.4 0.9 5.9e-09 35.8 0.1 2.2 2 1 1 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 AII58784.1 - 2.1e-09 37.6 0.0 3.8e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 AII58784.1 - 1.9e-05 24.8 0.0 3.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 AII58784.1 - 2.1e-05 24.5 0.0 4.5e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 AII58784.1 - 3.6e-05 23.6 0.0 7.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 AII58784.1 - 5.4e-05 23.1 0.0 0.00014 21.8 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 AII58784.1 - 0.031 14.5 0.0 0.054 13.7 0.0 1.4 1 0 0 1 1 1 0 PAS fold HisKA_7TM PF16927.5 AII58787.1 - 5.5e-54 183.5 21.9 7.3e-54 183.1 21.9 1.1 1 0 0 1 1 1 1 N-terminal 7TM region of histidine kinase PAS_8 PF13188.7 AII58787.1 - 4.7e-16 58.4 0.0 7e-07 29.1 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 AII58787.1 - 3.4e-14 52.8 0.0 2e-07 31.0 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 AII58787.1 - 4.9e-10 39.6 0.1 3.5e-05 24.0 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_7 PF12860.7 AII58787.1 - 1e-07 32.1 0.2 0.0012 18.9 0.1 3.3 2 1 0 3 3 3 2 PAS fold PAS_4 PF08448.10 AII58787.1 - 8.6e-07 29.2 0.0 0.00041 20.6 0.0 3.1 2 1 0 2 2 2 1 PAS fold zf-C2H2_9 PF16293.5 AII58787.1 - 0.041 13.7 1.9 2 8.3 0.0 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) PAS_10 PF13596.6 AII58787.1 - 0.056 14.0 0.0 0.16 12.6 0.0 1.8 1 1 0 1 1 1 0 PAS domain HATPase_c PF02518.26 AII58788.1 - 5.1e-21 75.3 0.1 1.7e-20 73.6 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 AII58788.1 - 2.7e-20 72.6 0.1 6e-20 71.5 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 AII58788.1 - 7e-17 61.2 0.0 6.5e-16 58.1 0.0 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 AII58788.1 - 2.1e-05 24.3 0.0 4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.6 AII58788.1 - 0.00039 20.3 0.0 0.00089 19.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 AII58788.1 - 0.0031 17.5 0.0 0.0088 16.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PAS_9 PF13426.7 AII58788.1 - 0.12 12.6 0.0 0.33 11.2 0.0 1.8 1 0 0 1 1 1 0 PAS domain 7TM-7TMR_HD PF07698.11 AII58790.1 - 0.0068 16.2 1.1 0.0076 16.0 1.1 1.0 1 0 0 1 1 1 1 7TM receptor with intracellular HD hydrolase DUF202 PF02656.15 AII58790.1 - 0.039 14.4 5.2 0.18 12.3 3.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Syndecan PF01034.20 AII58790.1 - 0.057 13.3 4.0 0.089 12.7 0.1 2.0 2 0 0 2 2 2 0 Syndecan domain PgaD PF13994.6 AII58790.1 - 0.14 12.3 1.5 0.25 11.4 0.7 1.6 1 1 1 2 2 2 0 PgaD-like protein SPT_ssu-like PF11779.8 AII58790.1 - 0.24 11.1 2.0 1.1 8.9 0.3 2.0 2 0 0 2 2 2 0 Small subunit of serine palmitoyltransferase-like SNARE PF05739.19 AII58790.1 - 3.9 7.5 6.2 5.4 7.1 0.0 2.1 2 0 0 2 2 2 0 SNARE domain SecD-TM1 PF13721.6 AII58791.1 - 0.21 12.1 1.1 0.51 10.8 0.5 2.0 1 1 1 2 2 2 0 SecD export protein N-terminal TM region HemY_N PF07219.13 AII58791.1 - 3.6 7.8 15.0 1.3 9.2 0.1 3.1 2 1 1 3 3 3 0 HemY protein N-terminus # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Dehalococcoides_mccartyi_CG1-ASM83092v1/GCA_000830925.1_ASM83092v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Dehalococcoides_mccartyi_CG1-ASM83092v1/GCA_000830925.1_ASM83092v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Dehalococcoides_mccartyi_CG1-ASM83092v1/GCA_000830925.1_ASM83092v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Dehalococcoides_mccartyi_CG1-ASM83092v1/GCA_000830925.1_ASM83092v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 02:13:48 2019 # [ok]