# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Kinase-PPPase PF03618.14 ACL93468.1 - 2.2e-91 306.1 0.0 2.6e-91 306.0 0.0 1.0 1 0 0 1 1 1 1 Kinase/pyrophosphorylase Maf PF02545.14 ACL93469.1 - 9.6e-34 116.6 0.0 1.1e-33 116.5 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein DUF905 PF06006.12 ACL93469.1 - 0.17 11.9 0.0 0.51 10.4 0.0 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF905) Shikimate_dh_N PF08501.11 ACL93470.1 - 2.2e-28 98.3 0.0 4.5e-28 97.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 ACL93470.1 - 1.6e-11 44.4 0.0 2.6e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 ACL93470.1 - 0.003 17.8 0.9 0.0061 16.8 0.3 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 ACL93470.1 - 0.02 14.2 2.0 0.033 13.5 2.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.17 ACL93470.1 - 0.022 15.4 0.2 0.042 14.4 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent SDH_C PF18317.1 ACL93470.1 - 0.056 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate 5'-dehydrogenase C-terminal domain CoaE PF01121.20 ACL93471.1 - 9.1e-41 139.5 0.0 1.1e-40 139.2 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 ACL93471.1 - 0.00011 22.8 0.0 0.00051 20.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ACL93471.1 - 0.015 15.4 0.6 0.55 10.4 0.3 2.5 1 1 0 1 1 1 0 AAA domain GSH-S_N PF02951.14 ACL93471.1 - 0.032 14.4 0.0 0.054 13.6 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, N-terminal domain RNase_T PF00929.24 ACL93472.1 - 5.3e-35 121.4 0.0 7.4e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 Exonuclease RNase_H_2 PF13482.6 ACL93472.1 - 0.015 15.3 0.0 0.044 13.8 0.0 1.7 1 1 0 1 1 1 0 RNase_H superfamily Amidohydro_3 PF07969.11 ACL93472.1 - 0.044 13.3 0.1 0.053 13.0 0.1 1.2 1 0 0 1 1 1 0 Amidohydrolase family DNApol_Exo PF18136.1 ACL93472.1 - 0.062 12.4 0.0 0.065 12.4 0.0 1.2 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain ECH_1 PF00378.20 ACL93473.1 - 1.8e-82 276.4 1.3 2e-82 276.3 1.3 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ACL93473.1 - 1.8e-37 129.6 3.5 1.6e-34 119.9 1.7 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 ACL93473.1 - 0.048 13.6 0.0 0.52 10.3 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 Ribosomal_S20p PF01649.18 ACL93474.2 - 1.4e-24 86.5 4.4 1.9e-24 86.1 4.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S20 TetR_C_15 PF17918.1 ACL93474.2 - 0.12 13.1 1.1 0.15 12.8 0.9 1.3 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Bac_DnaA PF00308.18 ACL93475.1 - 8.4e-90 300.4 0.0 1.2e-89 299.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial dnaA protein Bac_DnaA_C PF08299.11 ACL93475.1 - 1.1e-28 99.0 0.0 2e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial dnaA protein helix-turn-helix IstB_IS21 PF01695.17 ACL93475.1 - 1.6e-13 50.8 0.0 3.1e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein DnaA_N PF11638.8 ACL93475.1 - 1.3e-12 47.3 0.0 2.4e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 DnaA N-terminal domain AAA PF00004.29 ACL93475.1 - 1.6e-09 38.3 0.0 8.6e-09 35.9 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ACL93475.1 - 1.1e-05 25.9 0.3 0.00019 21.9 0.3 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ACL93475.1 - 0.00038 20.7 0.4 0.74 10.1 0.1 3.4 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 ACL93475.1 - 0.00041 20.4 0.0 0.0052 16.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 ACL93475.1 - 0.0031 17.5 0.0 0.02 14.9 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit RuvB_N PF05496.12 ACL93475.1 - 0.004 16.9 0.0 0.02 14.6 0.0 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 ACL93475.1 - 0.041 14.1 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ACL93475.1 - 0.049 13.5 0.0 0.18 11.7 0.0 2.0 1 1 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 ACL93475.1 - 0.052 13.5 0.0 0.21 11.5 0.0 1.9 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 ACL93475.1 - 0.23 11.0 0.0 1.5 8.3 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region 2OG-FeII_Oxy_2 PF13532.6 ACL93476.1 - 3.3e-51 174.3 0.0 3.7e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HSP70 PF00012.20 ACL93477.1 - 8.8e-277 919.2 8.6 1e-276 919.0 8.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ACL93477.1 - 1.1e-17 63.9 0.3 3.7e-15 55.6 0.1 2.8 2 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 ACL93477.1 - 3.1e-05 23.8 0.1 8.3e-05 22.4 0.1 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 ACL93477.1 - 0.0062 16.9 5.6 0.15 12.5 0.0 3.4 3 1 0 3 3 3 2 Cell division protein FtsA DP PF08781.10 ACL93477.1 - 0.044 13.7 0.1 0.14 12.0 0.1 1.8 1 0 0 1 1 1 0 Transcription factor DP DnaJ_C PF01556.18 ACL93478.1 - 2.3e-40 138.1 0.0 2.9e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ACL93478.1 - 1.5e-24 85.8 0.0 2.3e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 ACL93478.1 - 1.2e-10 41.6 13.8 1.2e-10 41.6 13.8 1.9 2 0 0 2 2 2 1 DnaJ central domain SCP_3 PF17844.1 ACL93478.1 - 0.0078 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial SCP ortholog HypA PF01155.19 ACL93478.1 - 0.03 14.3 5.2 0.05 13.6 1.0 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 ACL93478.1 - 0.075 13.0 17.9 0.59 10.1 2.7 2.6 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein MutS_V PF00488.21 ACL93479.1 - 3.8e-82 274.9 0.0 5.9e-82 274.3 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 ACL93479.1 - 5.9e-40 136.0 0.0 9.8e-40 135.3 0.0 1.4 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 ACL93479.1 - 1.3e-32 113.6 0.1 2.4e-32 112.7 0.1 1.5 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 ACL93479.1 - 3.6e-18 65.7 0.0 6.3e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 ACL93479.1 - 5.9e-17 62.2 0.0 1.4e-16 61.0 0.0 1.7 1 0 0 1 1 1 1 MutS domain II AAA_27 PF13514.6 ACL93479.1 - 0.0013 18.4 0.1 0.026 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain SIMPL PF04402.14 ACL93479.1 - 0.084 13.3 2.8 0.24 11.8 1.6 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF541) GlnD_UR_UTase PF08335.11 ACL93480.1 - 1.5e-31 109.5 0.0 3.2e-31 108.4 0.0 1.6 1 0 0 1 1 1 1 GlnD PII-uridylyltransferase ACT PF01842.25 ACL93480.1 - 2.9e-10 39.7 0.2 0.0006 19.5 0.0 2.9 2 0 0 2 2 2 2 ACT domain HD PF01966.22 ACL93480.1 - 4.6e-10 39.8 0.2 3.1e-09 37.1 0.1 2.4 2 0 0 2 2 2 1 HD domain ACT_4 PF13291.6 ACL93480.1 - 1.6e-05 25.4 0.0 0.067 13.8 0.0 2.6 2 0 0 2 2 2 2 ACT domain GlnE PF03710.15 ACL93480.1 - 0.00081 18.9 0.0 0.0019 17.6 0.0 1.6 1 0 0 1 1 1 1 Glutamate-ammonia ligase adenylyltransferase ACT_6 PF13740.6 ACL93480.1 - 0.0013 18.7 0.1 0.028 14.4 0.0 2.7 2 0 0 2 2 2 1 ACT domain NTP_transf_2 PF01909.23 ACL93480.1 - 0.0087 16.3 0.0 0.019 15.3 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain MoaC PF01967.21 ACL93481.1 - 1.6e-53 180.5 2.7 1.8e-53 180.3 2.7 1.0 1 0 0 1 1 1 1 MoaC family MoCF_biosynth PF00994.24 ACL93482.1 - 1.5e-34 118.7 0.4 1.9e-34 118.4 0.4 1.0 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoaE PF02391.17 ACL93483.1 - 9.7e-31 106.4 0.2 1.2e-30 106.1 0.2 1.1 1 0 0 1 1 1 1 MoaE protein ThiS PF02597.20 ACL93484.1 - 1.6e-13 51.1 0.0 1.8e-13 50.9 0.0 1.0 1 0 0 1 1 1 1 ThiS family Mob_synth_C PF06463.13 ACL93485.1 - 3.5e-38 130.4 0.0 5e-38 129.9 0.0 1.2 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 ACL93485.1 - 5e-25 88.8 0.0 1e-24 87.8 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 ACL93485.1 - 4.7e-08 33.4 0.0 1e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 ACL93485.1 - 5.5e-05 23.3 0.0 0.00029 21.0 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain NTP_transf_3 PF12804.7 ACL93486.1 - 2.5e-34 119.0 7.2 3.2e-34 118.6 7.2 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 ACL93486.1 - 0.028 14.2 0.2 0.075 12.8 0.0 1.8 2 0 0 2 2 2 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DUF2064 PF09837.9 ACL93486.1 - 0.053 13.3 0.7 2.1 8.2 0.3 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2064) Ald_Xan_dh_C2 PF02738.18 ACL93488.1 - 1.3e-56 192.2 6.0 1.6e-31 109.4 0.0 3.1 2 1 0 3 3 3 3 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 ACL93488.1 - 6.6e-06 26.5 0.1 0.0077 16.6 0.0 2.7 2 0 0 2 2 2 2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 ACL93489.1 - 3e-30 104.0 0.9 3e-30 104.0 0.9 2.2 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fer2 PF00111.27 ACL93489.1 - 6.7e-08 32.4 0.1 6.7e-08 32.4 0.1 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 ACL93489.1 - 0.00011 22.2 0.7 0.00011 22.2 0.7 1.6 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 ACL93489.1 - 0.00099 19.1 0.4 0.03 14.4 0.5 2.5 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain OSK PF17182.4 ACL93489.1 - 0.047 12.9 0.1 0.31 10.3 0.0 1.9 2 0 0 2 2 2 0 OSK domain MliC PF09864.9 ACL93490.2 - 4.3e-14 52.2 0.1 5.8e-14 51.8 0.1 1.2 1 0 0 1 1 1 1 Membrane-bound lysozyme-inhibitor of c-type lysozyme NAD_binding_7 PF13241.6 ACL93491.1 - 1.2e-11 45.0 0.9 1.3e-09 38.4 0.3 3.1 2 1 0 2 2 2 1 Putative NAD(P)-binding CysG_dimeriser PF10414.9 ACL93491.1 - 1.2e-11 44.1 8.4 2.5e-11 43.1 6.2 2.7 2 1 1 3 3 3 1 Sirohaem synthase dimerisation region TP_methylase PF00590.20 ACL93491.1 - 7.3e-06 26.1 1.4 7.3e-06 26.1 1.4 2.3 2 2 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_M PF14824.6 ACL93491.1 - 0.003 17.0 0.0 0.0069 15.8 0.0 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Borealin PF10512.9 ACL93491.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Cell division cycle-associated protein 8 Sugar_tr PF00083.24 ACL93492.1 - 7.1e-35 120.7 33.1 2.3e-23 82.8 8.4 3.1 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 ACL93492.1 - 1.4e-20 73.5 30.5 1.4e-20 73.5 30.5 2.3 2 0 0 2 2 2 1 Major Facilitator Superfamily PAS_3 PF08447.12 ACL93493.1 - 4.3e-35 119.9 2.3 2.3e-10 40.6 0.0 4.3 4 0 0 4 4 4 4 PAS fold PAS_4 PF08448.10 ACL93493.1 - 8.7e-28 96.8 16.4 4.4e-16 59.1 0.8 5.1 5 0 0 5 5 5 4 PAS fold HATPase_c PF02518.26 ACL93493.1 - 3.1e-26 92.1 0.0 1.1e-25 90.3 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ACL93493.1 - 2.2e-25 89.0 0.0 4.5e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain PAS PF00989.25 ACL93493.1 - 7.3e-24 84.0 0.4 3.5e-11 43.1 0.0 4.4 4 0 0 4 4 4 3 PAS fold HisKA PF00512.25 ACL93493.1 - 1.3e-16 60.4 0.8 5.1e-15 55.3 0.1 3.4 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 ACL93493.1 - 4.9e-14 52.4 0.0 6.6e-05 23.1 0.0 4.2 4 0 0 4 4 4 2 PAS domain PAS_8 PF13188.7 ACL93493.1 - 2.2e-11 43.5 0.2 6.1e-05 22.9 0.0 3.6 3 0 0 3 3 3 2 PAS domain PAS_11 PF14598.6 ACL93493.1 - 5.9e-06 26.4 0.0 0.0066 16.6 0.0 2.6 3 0 0 3 3 3 2 PAS domain PAS_7 PF12860.7 ACL93493.1 - 0.00068 19.8 0.0 0.38 10.9 0.0 3.4 3 1 0 3 3 3 1 PAS fold PAS_10 PF13596.6 ACL93493.1 - 0.0017 19.0 0.0 0.28 11.8 0.0 3.3 3 0 0 3 3 3 1 PAS domain PKHD_C PF18331.1 ACL93494.1 - 3.9e-20 71.6 1.1 8e-20 70.6 1.1 1.6 1 0 0 1 1 1 1 PKHD-type hydroxylase C-terminal domain 2OG-FeII_Oxy_3 PF13640.6 ACL93494.1 - 1.2e-13 51.8 0.0 1.6e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cupin_2 PF07883.11 ACL93494.1 - 0.0083 15.8 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Cupin domain TonB_dep_Rec PF00593.24 ACL93495.2 - 4e-53 181.9 28.4 4e-53 181.9 28.4 2.1 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 ACL93495.2 - 1.1e-18 67.7 1.5 3.9e-18 66.0 1.5 2.0 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain LysE PF01810.18 ACL93496.1 - 6.7e-29 100.7 10.5 7.8e-29 100.5 10.5 1.0 1 0 0 1 1 1 1 LysE type translocator IncE PF17627.2 ACL93496.1 - 0.12 12.4 4.9 0.55 10.2 0.3 2.3 2 0 0 2 2 2 0 Inclusion membrane protein E Ribonuclease_T2 PF00445.18 ACL93497.1 - 2.2e-16 60.7 0.0 3.9e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease T2 family PIN PF01850.21 ACL93498.1 - 1e-14 55.1 0.1 1.1e-14 54.9 0.1 1.0 1 0 0 1 1 1 1 PIN domain DUF4411 PF14367.6 ACL93498.1 - 0.016 15.2 0.1 0.28 11.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4411) DUF5615 PF18480.1 ACL93498.1 - 0.034 13.9 0.1 0.073 12.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5615) MazE_antitoxin PF04014.18 ACL93499.1 - 1.5e-08 34.4 0.2 2.3e-08 33.8 0.0 1.4 2 0 0 2 2 2 1 Antidote-toxin recognition MazE, bacterial antitoxin RNase_PH PF01138.21 ACL93500.1 - 6.6e-46 156.1 0.0 9.9e-22 77.9 0.0 2.3 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 PNPase PF03726.14 ACL93500.1 - 4.9e-20 71.8 0.1 1.6e-19 70.2 0.1 1.9 1 0 0 1 1 1 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain RNase_PH_C PF03725.15 ACL93500.1 - 3.5e-19 68.6 0.7 4.9e-11 42.5 0.1 2.8 2 0 0 2 2 2 2 3' exoribonuclease family, domain 2 S1 PF00575.23 ACL93500.1 - 2.6e-18 66.1 1.9 5.7e-18 65.0 1.9 1.6 1 0 0 1 1 1 1 S1 RNA binding domain KH_1 PF00013.29 ACL93500.1 - 1.5e-09 37.6 1.9 1.5e-09 37.6 1.9 2.1 2 0 0 2 2 2 1 KH domain Cauli_DNA-bind PF03310.13 ACL93500.1 - 0.051 13.6 0.0 0.19 11.8 0.0 1.9 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein Ribosomal_S15 PF00312.22 ACL93501.1 - 2.7e-36 123.6 2.0 3.1e-36 123.5 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S15 TruB_N PF01509.18 ACL93502.1 - 2.6e-51 173.9 0.0 3.7e-51 173.4 0.0 1.2 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 ACL93502.1 - 2.7e-15 56.3 0.2 6.2e-15 55.1 0.2 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_C PF09142.11 ACL93502.1 - 4.5e-05 23.1 1.7 0.00046 19.9 0.7 2.8 2 1 0 2 2 2 1 tRNA Pseudouridine synthase II, C terminal TruB-C_2 PF09157.11 ACL93502.1 - 0.016 15.2 0.1 0.036 14.1 0.1 1.6 1 0 0 1 1 1 0 Pseudouridine synthase II TruB, C-terminal PHA_gran_rgn PF09650.10 ACL93502.1 - 0.071 13.4 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) RBFA PF02033.18 ACL93503.1 - 1.1e-27 96.5 0.0 1.4e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Ribosome-binding factor A DLH PF01738.18 ACL93504.1 - 1.7e-10 40.9 0.0 2.2e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Spc7_N PF15402.6 ACL93505.1 - 0.069 11.4 0.1 0.087 11.1 0.1 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF2939 PF11159.8 ACL93506.1 - 1.2e-16 60.9 3.5 1.7e-16 60.4 3.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2939) YcxB PF14317.6 ACL93507.2 - 5.5e-05 22.8 0.0 7.8e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 YcxB-like protein IF-2 PF11987.8 ACL93508.2 - 2.7e-36 123.9 0.3 6.8e-36 122.6 0.3 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU PF00009.27 ACL93508.2 - 5.6e-34 117.4 2.5 1.8e-32 112.5 2.5 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF2_N PF04760.15 ACL93508.2 - 3e-12 46.2 0.0 5.7e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region GTP_EFTU_D2 PF03144.25 ACL93508.2 - 1.3e-11 44.7 5.1 1.4e-06 28.5 2.0 3.1 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ACL93508.2 - 4.4e-10 39.6 0.1 8.9e-10 38.7 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_assoc PF08364.11 ACL93508.2 - 5.6e-10 39.3 3.3 1.4e-09 38.0 3.3 1.8 1 0 0 1 1 1 1 Bacterial translation initiation factor IF-2 associated region FeoB_N PF02421.18 ACL93508.2 - 2e-05 24.1 0.2 6.5e-05 22.5 0.2 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 ACL93508.2 - 2.8e-05 23.6 0.1 0.00024 20.6 0.1 2.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 ACL93508.2 - 0.00013 22.0 0.3 0.092 12.6 0.1 2.4 1 1 1 2 2 2 2 RsgA GTPase Arf PF00025.21 ACL93508.2 - 0.00088 18.8 0.0 0.0019 17.7 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family MeaB PF03308.16 ACL93508.2 - 0.002 17.2 2.4 0.008 15.2 1.2 2.3 1 1 1 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 ACL93508.2 - 0.012 15.8 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 ACL93508.2 - 0.025 14.3 0.1 0.079 12.7 0.1 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 ACL93508.2 - 0.063 13.8 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1_Xtn PF16897.5 ACL93508.2 - 0.13 12.3 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain GTP_EFTU_D4 PF14578.6 ACL93508.2 - 6.4 6.8 9.0 0.65 9.9 0.9 2.8 3 0 0 3 3 3 0 Elongation factor Tu domain 4 DUF448 PF04296.13 ACL93509.1 - 4e-17 61.8 0.0 7.1e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF448) KH_5 PF13184.6 ACL93510.1 - 5.8e-32 109.6 0.4 1.2e-28 99.0 0.2 3.0 2 0 0 2 2 2 2 NusA-like KH domain NusA_N PF08529.11 ACL93510.1 - 1e-26 93.7 4.3 1e-26 93.7 4.3 2.0 2 0 0 2 2 2 1 NusA N-terminal domain HHH_5 PF14520.6 ACL93510.1 - 1.7e-09 38.1 1.1 0.00094 19.7 0.0 2.9 2 0 0 2 2 2 2 Helix-hairpin-helix domain KH_2 PF07650.17 ACL93510.1 - 1.8e-06 27.7 0.3 2.5e-05 24.0 0.0 2.9 2 0 0 2 2 2 1 KH domain S1 PF00575.23 ACL93510.1 - 2.9e-05 24.3 0.6 2.9e-05 24.3 0.6 2.8 2 0 0 2 2 2 1 S1 RNA binding domain KH_1 PF00013.29 ACL93510.1 - 0.00023 20.9 3.2 0.026 14.4 0.0 4.1 5 0 0 5 5 5 1 KH domain KH_4 PF13083.6 ACL93510.1 - 0.026 14.4 0.4 0.095 12.6 0.0 2.1 2 0 0 2 2 2 0 KH domain DUF4332 PF14229.6 ACL93510.1 - 0.06 13.6 0.4 1.4 9.2 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4332) Ribosomal_S17e PF00833.18 ACL93510.1 - 0.078 12.9 3.2 0.74 9.7 0.0 2.7 2 0 0 2 2 2 0 Ribosomal S17 DUF2920 PF11144.8 ACL93510.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) PGBA_C PF15437.6 ACL93510.1 - 5.6 7.4 11.8 0.67 10.3 4.1 2.6 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal DUF150 PF02576.17 ACL93511.1 - 4e-23 81.6 0.0 6.9e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 RimP N-terminal domain DUF150_C PF17384.2 ACL93511.1 - 6e-12 45.5 0.1 1e-11 44.8 0.1 1.4 1 0 0 1 1 1 1 RimP C-terminal SH3 domain AstE_AspA PF04952.14 ACL93511.1 - 0.12 11.5 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Pyrophosphatase PF00719.19 ACL93512.1 - 4.5e-55 185.8 0.0 5.1e-55 185.6 0.0 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase DUF4345 PF14248.6 ACL93513.1 - 0.0055 16.6 8.5 0.013 15.4 8.3 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4345) Methyltransf_4 PF02390.17 ACL93514.1 - 1.6e-45 154.6 0.0 2e-45 154.4 0.0 1.0 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 ACL93514.1 - 5.5e-06 27.0 0.0 1.6e-05 25.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ACL93514.1 - 4.8e-05 23.9 0.0 0.0001 22.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ACL93514.1 - 0.0039 17.0 0.0 0.0053 16.5 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 ACL93514.1 - 0.051 13.4 0.0 0.17 11.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain S-AdoMet_synt_C PF02773.16 ACL93515.1 - 6.9e-60 201.0 0.0 1.7e-59 199.8 0.0 1.7 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 ACL93515.1 - 2.8e-38 130.8 0.0 5.2e-38 130.0 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 ACL93515.1 - 3.6e-35 120.6 0.0 7.1e-35 119.7 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Lactococcin_972 PF09683.10 ACL93515.1 - 0.03 14.9 0.3 0.067 13.8 0.3 1.6 1 0 0 1 1 1 0 Bacteriocin (Lactococcin_972) HTH_3 PF01381.22 ACL93516.1 - 1.3e-10 41.2 0.1 1.9e-10 40.6 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 ACL93516.1 - 6.4e-08 32.8 0.6 1.3e-07 31.9 0.6 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 ACL93516.1 - 1.2e-07 31.6 0.1 1.8e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 ACL93516.1 - 0.0013 19.1 0.0 0.0022 18.4 0.0 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain YdaS_antitoxin PF15943.5 ACL93516.1 - 0.0046 16.8 0.0 0.0083 16.0 0.0 1.4 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT CN_hydrolase PF00795.22 ACL93517.1 - 3.6e-36 124.8 0.0 4.8e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Urate_ox_N PF06181.11 ACL93517.1 - 0.024 14.0 0.8 0.037 13.4 0.8 1.2 1 0 0 1 1 1 0 Urate oxidase N-terminal CorC_HlyC PF03471.17 ACL93518.1 - 1.7e-18 66.4 0.5 7.7e-18 64.3 0.0 2.0 2 0 0 2 2 2 1 Transporter associated domain CBS PF00571.28 ACL93518.1 - 4.5e-14 52.6 2.1 5.4e-06 26.8 0.2 2.5 2 0 0 2 2 2 2 CBS domain UPF0054 PF02130.17 ACL93519.3 - 2e-35 121.4 0.0 2.2e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 Reprolysin_4 PF13583.6 ACL93519.3 - 0.0038 16.9 0.1 0.0093 15.6 0.0 1.5 1 1 1 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 ACL93519.3 - 0.031 14.1 0.1 0.039 13.8 0.1 1.1 1 0 0 1 1 1 0 Matrixin PhoH PF02562.16 ACL93520.1 - 2.8e-85 284.9 0.0 3.7e-85 284.6 0.0 1.1 1 0 0 1 1 1 1 PhoH-like protein AAA_30 PF13604.6 ACL93520.1 - 2.2e-11 43.8 0.8 4.6e-11 42.8 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 ACL93520.1 - 1.3e-06 28.8 0.2 7.5e-06 26.3 0.2 2.0 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 ACL93520.1 - 0.0054 16.3 0.0 0.2 11.2 0.0 2.1 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_11 PF13086.6 ACL93520.1 - 0.013 15.3 0.0 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 ACL93520.1 - 0.027 14.2 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein SNF2_N PF00176.23 ACL93520.1 - 0.03 13.0 0.0 0.042 12.6 0.0 1.1 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_22 PF13401.6 ACL93520.1 - 0.044 14.1 0.2 7 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain BON PF04972.17 ACL93520.1 - 0.48 10.8 2.4 0.56 10.6 0.3 2.1 2 0 0 2 2 2 0 BON domain Radical_SAM PF04055.21 ACL93521.1 - 6.3e-33 114.5 0.0 1.2e-32 113.5 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 ACL93521.1 - 6.6e-31 106.3 0.2 1.3e-30 105.3 0.2 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 ACL93521.1 - 6.1e-08 32.5 0.0 1.4e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 TRAM domain Amdase PF17645.1 ACL93521.1 - 0.052 13.2 0.0 0.36 10.4 0.0 2.1 2 0 0 2 2 2 0 Arylmalonate decarboxylase TRAM_2 PF18693.1 ACL93521.1 - 0.097 12.9 0.0 0.99 9.6 0.0 2.3 1 1 0 1 1 1 0 TRAM domain B12-binding PF02310.19 ACL93521.1 - 0.098 12.7 0.4 1.1 9.3 0.0 2.6 3 0 0 3 3 3 0 B12 binding domain FUR PF01475.19 ACL93522.1 - 6.4e-42 142.5 1.2 7.2e-42 142.3 1.2 1.0 1 0 0 1 1 1 1 Ferric uptake regulator family RepL PF05732.11 ACL93522.1 - 0.013 14.9 0.0 0.29 10.6 0.0 2.0 2 0 0 2 2 2 0 Firmicute plasmid replication protein (RepL) HTH_23 PF13384.6 ACL93522.1 - 0.015 15.1 0.6 0.14 12.0 0.1 2.6 3 1 0 3 3 3 0 Homeodomain-like domain HTH_20 PF12840.7 ACL93522.1 - 0.02 15.0 0.1 0.032 14.3 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 ACL93522.1 - 0.024 14.7 0.0 0.18 11.9 0.1 2.2 2 0 0 2 2 2 0 Winged helix-turn helix Acetyltransf_1 PF00583.25 ACL93523.1 - 5.7e-14 52.3 0.0 7.2e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ACL93523.1 - 4.4e-08 33.1 0.0 4.9e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ACL93523.1 - 7.5e-08 32.7 0.0 9.5e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ACL93523.1 - 1.5e-07 31.3 0.0 2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 ACL93523.1 - 0.0037 17.0 0.1 0.0057 16.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ACL93523.1 - 0.0074 16.4 0.0 0.01 16.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ACL93523.1 - 0.022 15.4 0.0 0.027 15.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ACL93523.1 - 0.15 12.2 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Peptidase_M22 PF00814.25 ACL93524.1 - 8.4e-30 104.4 0.6 1.2e-29 103.9 0.6 1.1 1 0 0 1 1 1 1 Glycoprotease family DUF1131 PF06572.12 ACL93525.1 - 3e-06 27.1 0.0 4.3e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1131) Nitroreductase PF00881.24 ACL93526.1 - 2.5e-13 50.4 0.0 7e-12 45.7 0.0 2.1 1 1 0 1 1 1 1 Nitroreductase family Nfu_N PF08712.11 ACL93527.1 - 3.6e-30 103.9 0.0 7e-30 102.9 0.0 1.5 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 ACL93527.1 - 4.5e-28 97.2 0.0 6.3e-28 96.7 0.0 1.2 1 0 0 1 1 1 1 NifU-like domain p450 PF00067.22 ACL93528.2 - 4.7e-25 88.3 0.0 5.8e-19 68.2 0.0 2.3 2 0 0 2 2 2 2 Cytochrome P450 tRNA-synt_1b PF00579.25 ACL93529.1 - 3.3e-76 256.4 0.0 3.8e-76 256.2 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) ZnuA PF01297.17 ACL93529.1 - 0.15 11.4 0.0 0.84 9.0 0.0 2.0 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic MurJ PF03023.14 ACL93530.1 - 2.5e-95 319.7 25.3 3.1e-95 319.4 25.3 1.1 1 0 0 1 1 1 1 Lipid II flippase MurJ Polysacc_synt_C PF14667.6 ACL93530.1 - 1.6e-10 41.2 12.1 1.6e-10 41.2 12.1 3.4 3 1 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain MatE PF01554.18 ACL93530.1 - 4e-09 36.3 1.9 4e-09 36.3 1.9 3.7 4 0 0 4 4 4 3 MatE MCPsignal PF00015.21 ACL93531.1 - 7.5e-51 172.3 19.6 7.5e-51 172.3 19.6 3.6 4 0 0 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 ACL93531.1 - 2e-08 34.5 10.7 1.6e-07 31.6 0.1 5.4 5 1 0 5 5 5 1 HAMP domain DUF1664 PF07889.12 ACL93531.1 - 0.013 15.6 9.5 9 6.4 0.2 4.6 4 3 0 4 4 4 0 Protein of unknown function (DUF1664) Noelin-1 PF12308.8 ACL93531.1 - 0.045 13.7 4.4 2.2 8.3 0.4 3.2 4 0 0 4 4 4 0 Neurogenesis glycoprotein BLOC1_2 PF10046.9 ACL93531.1 - 0.19 12.1 13.6 4 7.8 0.1 5.4 5 1 1 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 ACL93531.1 - 0.41 11.2 5.7 7.8 7.0 0.7 3.8 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Syntaxin-6_N PF09177.11 ACL93531.1 - 1.9 9.1 14.4 12 6.5 0.2 4.4 3 1 1 4 4 4 0 Syntaxin 6, N-terminal Methyltransf_24 PF13578.6 ACL93532.1 - 3.2e-11 44.2 0.0 5.9e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 ACL93532.1 - 0.00014 21.1 0.0 0.00022 20.5 0.0 1.3 1 1 0 1 1 1 1 O-methyltransferase Rieske PF00355.26 ACL93533.1 - 5.3e-07 29.5 0.0 6.4e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain YCII PF03795.14 ACL93534.1 - 3.2e-21 75.6 0.0 3.7e-21 75.4 0.0 1.0 1 0 0 1 1 1 1 YCII-related domain NAD_Gly3P_dh_C PF07479.14 ACL93535.1 - 3.9e-45 153.6 1.7 5.9e-45 153.0 1.7 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 ACL93535.1 - 7.6e-44 149.5 0.1 1.2e-43 148.8 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 ACL93535.1 - 5e-07 29.5 0.1 9.2e-07 28.6 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 ACL93535.1 - 1.6e-05 24.8 1.6 4.5e-05 23.4 1.6 1.8 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 ACL93535.1 - 2.7e-05 24.7 0.4 2.7e-05 24.7 0.4 2.7 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 ACL93535.1 - 5.4e-05 23.4 0.3 0.00018 21.7 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_2 PF07992.14 ACL93535.1 - 0.0041 16.4 0.1 0.0098 15.2 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ACL93535.1 - 0.0047 17.5 0.2 0.013 16.1 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GFO_IDH_MocA PF01408.22 ACL93535.1 - 0.02 15.7 1.3 0.037 14.9 0.2 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold 2-Hacid_dh_C PF02826.19 ACL93535.1 - 0.031 13.6 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 ACL93535.1 - 0.064 13.7 0.0 0.32 11.5 0.0 2.1 2 1 1 3 3 3 0 Putative NAD(P)-binding Peptidase_M22 PF00814.25 ACL93536.1 - 6.9e-89 298.1 0.5 8.4e-89 297.9 0.5 1.1 1 0 0 1 1 1 1 Glycoprotease family Porphobil_deam PF01379.20 ACL93537.1 - 1.3e-75 253.4 0.0 1.7e-75 253.0 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 ACL93537.1 - 1.1e-08 35.4 0.3 2.2e-08 34.4 0.3 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain HEM4 PF02602.15 ACL93538.1 - 1.1e-26 93.6 2.8 1.3e-26 93.4 2.8 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Mitofilin PF09731.9 ACL93539.2 - 6.2e-07 28.7 0.6 8.9e-07 28.1 0.6 1.3 1 1 0 1 1 1 1 Mitochondrial inner membrane protein TPR_4 PF07721.14 ACL93539.2 - 0.051 14.2 1.5 0.051 14.2 1.5 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 ACL93539.2 - 0.09 13.3 0.0 0.09 13.3 0.0 2.9 4 1 0 4 4 4 0 Tetratricopeptide repeat HemY_N PF07219.13 ACL93540.1 - 5.6e-22 78.0 12.1 5.6e-22 78.0 12.1 5.0 4 2 2 6 6 6 1 HemY protein N-terminus TPR_19 PF14559.6 ACL93540.1 - 8.5e-06 26.2 32.8 0.052 14.1 1.8 5.2 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_4 PF07721.14 ACL93540.1 - 0.044 14.4 5.5 0.044 14.4 5.5 10.3 12 0 0 12 12 12 0 Tetratricopeptide repeat Promethin PF16015.5 ACL93540.1 - 7.4 6.6 9.8 10 6.1 8.6 1.9 2 0 0 2 2 2 0 Promethin 3HCDH_N PF02737.18 ACL93541.1 - 1.2e-59 201.2 2.0 2.6e-59 200.1 2.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 ACL93541.1 - 3.2e-38 131.5 1.5 8e-38 130.2 1.5 1.6 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 ACL93541.1 - 6.3e-31 106.9 0.7 9.2e-23 80.7 0.1 3.6 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 ACL93541.1 - 3e-26 92.7 0.6 5.4e-26 91.9 0.6 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase NAD_binding_2 PF03446.15 ACL93541.1 - 0.012 15.8 0.5 0.031 14.4 0.5 1.8 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DAO PF01266.24 ACL93541.1 - 0.012 15.2 0.1 0.022 14.4 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ACL93541.1 - 0.041 13.1 0.3 0.073 12.3 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain F420_oxidored PF03807.17 ACL93541.1 - 0.045 14.3 0.6 0.14 12.7 0.6 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent MtrH PF02007.18 ACL93541.1 - 0.084 12.0 0.9 1.3 8.1 0.0 2.2 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase MtrH subunit UDPG_MGDP_dh_N PF03721.14 ACL93541.1 - 0.091 12.3 0.1 0.2 11.2 0.1 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thiolase_N PF00108.23 ACL93542.1 - 3.9e-50 170.6 0.2 2.3e-46 158.3 0.0 2.4 2 0 0 2 2 2 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 ACL93542.1 - 2.3e-43 146.8 2.6 4.9e-43 145.7 0.5 2.2 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ACL93542.1 - 0.00036 20.2 1.2 0.00064 19.4 0.4 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 ACL93542.1 - 0.0037 17.4 0.1 0.012 15.7 0.1 2.0 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 ACL93542.1 - 0.1 12.5 1.3 1.5 8.7 0.2 2.8 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Acyl-CoA_dh_1 PF00441.24 ACL93544.1 - 3.1e-44 150.8 0.2 4.6e-44 150.3 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ACL93544.1 - 3.4e-30 105.0 0.1 5.7e-30 104.3 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ACL93544.1 - 8.1e-25 86.9 0.0 2.1e-24 85.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ACL93544.1 - 5.6e-13 49.3 0.0 9.7e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 ACL93544.1 - 0.00023 21.7 0.0 0.00043 20.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_C PF12806.7 ACL93545.1 - 1e-32 112.9 0.6 2.5e-32 111.6 0.5 1.8 2 0 0 2 2 2 1 Acetyl-CoA dehydrogenase C-terminal like Acyl-CoA_dh_1 PF00441.24 ACL93545.1 - 1.8e-19 70.4 0.0 1.3e-18 67.6 0.0 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ACL93545.1 - 5.2e-16 58.6 0.0 1.2e-15 57.4 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ACL93545.1 - 1.4e-14 54.7 0.0 2.8e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain AcylCoA_DH_N PF12418.8 ACL93545.1 - 6.3e-09 35.7 0.0 1.4e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase N terminal Acyl-CoA_dh_2 PF08028.11 ACL93545.1 - 0.011 16.0 0.0 0.091 13.0 0.0 2.3 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase, C-terminal domain MerR-DNA-bind PF09278.11 ACL93546.1 - 7.2e-14 52.1 6.4 7.2e-14 52.1 6.4 2.1 1 1 1 2 2 2 1 MerR, DNA binding MerR_1 PF13411.6 ACL93546.1 - 7.3e-14 51.6 0.1 1.3e-13 50.8 0.1 1.4 1 1 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 ACL93546.1 - 5.8e-07 29.2 0.0 1.3e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 MerR family regulatory protein Mce4_CUP1 PF11887.8 ACL93546.1 - 0.0011 18.5 0.0 0.0015 18.1 0.0 1.1 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative PI3K_P85_iSH2 PF16454.5 ACL93546.1 - 0.003 17.2 0.5 0.0039 16.8 0.5 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain PspA_IM30 PF04012.12 ACL93546.1 - 0.012 15.2 0.5 0.014 15.0 0.5 1.2 1 0 0 1 1 1 0 PspA/IM30 family FUSC PF04632.12 ACL93546.1 - 0.024 13.2 3.9 0.028 13.0 3.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Vac_Fusion PF02346.16 ACL93546.1 - 0.036 13.7 3.5 0.18 11.5 0.4 2.7 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 HTH_38 PF13936.6 ACL93546.1 - 0.04 13.7 0.1 0.085 12.6 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain DegS PF05384.11 ACL93546.1 - 0.09 12.3 3.8 0.14 11.7 3.6 1.4 1 1 0 1 1 1 0 Sensor protein DegS UPF0242 PF06785.11 ACL93546.1 - 0.09 12.9 0.5 0.11 12.6 0.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DLP_helical PF18709.1 ACL93546.1 - 0.17 11.1 0.4 0.21 10.8 0.4 1.1 1 0 0 1 1 1 0 Dynamin-like helical domain F_actin_bind PF08919.10 ACL93546.1 - 0.5 10.5 5.1 6.3 6.9 0.1 3.2 2 2 1 3 3 3 0 F-actin binding Peptidase_S24 PF00717.23 ACL93547.1 - 1.9e-10 40.5 0.0 2.9e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like HTH_3 PF01381.22 ACL93547.1 - 0.046 13.8 0.0 0.46 10.6 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix tRNA-synt_1f PF01921.18 ACL93549.1 - 2.1e-119 398.7 0.0 2.6e-119 398.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (K) tRNA-synt_1g PF09334.11 ACL93549.1 - 0.0078 15.0 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 ACL93549.1 - 0.19 11.1 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain PGM_PMM_I PF02878.16 ACL93550.1 - 2.7e-36 124.3 0.0 5.7e-36 123.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 ACL93550.1 - 1.4e-27 96.2 0.0 2.8e-27 95.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 ACL93550.1 - 1.3e-12 48.2 0.2 3.4e-12 46.9 0.1 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 ACL93550.1 - 8.6e-10 38.7 0.0 2.1e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain AICARFT_IMPCHas PF01808.18 ACL93551.1 - 6.4e-116 386.9 1.0 7.9e-116 386.6 1.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 ACL93551.1 - 8.1e-25 86.9 0.0 1.6e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 MGS-like domain CoA_binding_2 PF13380.6 ACL93551.1 - 0.015 15.8 0.9 3.8 8.0 0.0 3.4 3 0 0 3 3 3 0 CoA binding domain DLH PF01738.18 ACL93552.1 - 4.9e-08 32.8 0.0 5.3e-06 26.1 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 ACL93552.1 - 7.5e-08 32.1 0.2 1.6e-05 24.5 0.2 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 ACL93552.1 - 7.2e-05 22.7 0.2 0.00046 20.1 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 ACL93552.1 - 0.016 14.1 0.0 0.026 13.4 0.0 1.4 1 1 0 1 1 1 0 Chlorophyllase enzyme Bac_GDH PF05088.12 ACL93553.1 - 0 1900.7 0.0 0 1898.9 0.0 1.7 1 1 0 1 1 1 1 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog PF00208.21 ACL93553.1 - 5.7e-05 22.9 0.1 0.00043 20.1 0.1 2.1 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AI-2E_transport PF01594.16 ACL93554.1 - 8.1e-45 153.4 23.8 9.2e-45 153.2 23.8 1.0 1 0 0 1 1 1 1 AI-2E family transporter ACP_syn_III_C PF08541.10 ACL93554.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal YMF19 PF02326.15 ACL93554.1 - 0.88 10.4 3.4 1.4 9.8 2.1 2.0 1 1 1 2 2 2 0 Plant ATP synthase F0 DUF853 PF05872.12 ACL93555.2 - 1.3e-249 828.9 1.3 1.6e-249 828.6 1.3 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) ResIII PF04851.15 ACL93555.2 - 0.00016 21.7 0.0 0.022 14.7 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ACL93555.2 - 0.00017 21.8 0.5 0.049 13.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.18 ACL93555.2 - 0.00032 20.1 0.1 0.00088 18.7 0.1 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family DUF87 PF01935.17 ACL93555.2 - 0.00047 20.3 0.1 0.00094 19.3 0.0 1.5 2 0 0 2 2 1 1 Helicase HerA, central domain AAA_10 PF12846.7 ACL93555.2 - 0.00084 18.4 0.0 0.12 11.3 0.0 2.1 2 0 0 2 2 2 2 AAA-like domain Zot PF05707.12 ACL93555.2 - 0.0013 18.4 0.0 0.0045 16.6 0.0 1.8 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_30 PF13604.6 ACL93555.2 - 0.0024 17.6 0.1 0.0024 17.6 0.1 2.1 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.9 ACL93555.2 - 0.0025 16.8 0.0 0.011 14.7 0.0 1.9 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.6 ACL93555.2 - 0.0038 17.6 7.0 0.025 15.0 0.6 3.3 2 1 0 2 2 2 1 AAA ATPase domain DUF2075 PF09848.9 ACL93555.2 - 0.007 15.7 0.1 3.9 6.6 0.2 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) CbiA PF01656.23 ACL93555.2 - 0.016 15.3 0.0 0.025 14.6 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain T2SSE PF00437.20 ACL93555.2 - 0.03 13.4 0.0 0.063 12.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.29 ACL93555.2 - 0.084 13.3 0.0 6.5 7.2 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 ACL93555.2 - 0.1 12.1 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region EAL PF00563.20 ACL93556.1 - 5.8e-74 248.6 0.0 1e-73 247.8 0.0 1.4 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 ACL93556.1 - 1.9e-42 144.7 0.0 3.1e-42 144.0 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain MHYT PF03707.16 ACL93556.1 - 2.3e-24 85.3 38.5 1.7e-10 40.9 4.5 4.6 4 0 0 4 4 4 4 Bacterial signalling protein N terminal repeat PAS_8 PF13188.7 ACL93556.1 - 2.7e-07 30.5 0.1 9.9e-06 25.5 0.1 2.6 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 ACL93556.1 - 4.1e-06 26.8 0.0 1e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 ACL93556.1 - 0.00068 19.9 0.0 0.0025 18.1 0.0 2.1 1 1 0 1 1 1 1 PAS fold PAS_9 PF13426.7 ACL93556.1 - 0.12 12.6 0.0 0.36 11.1 0.0 1.8 1 0 0 1 1 1 0 PAS domain GDP_Man_Dehyd PF16363.5 ACL93557.1 - 1.1e-55 189.3 0.0 1.6e-55 188.9 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ACL93557.1 - 8.7e-52 176.0 0.0 1.1e-51 175.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ACL93557.1 - 1.5e-15 56.9 0.0 9.6e-14 51.0 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ACL93557.1 - 2.7e-15 56.2 0.0 4.1e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 ACL93557.1 - 8.8e-14 51.3 0.1 1.3e-12 47.5 0.1 2.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 ACL93557.1 - 1.5e-07 30.9 0.1 9.6e-07 28.2 0.0 2.2 2 1 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 ACL93557.1 - 0.00017 21.6 0.0 0.00033 20.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ACL93557.1 - 0.0019 17.8 0.1 0.0065 16.1 0.1 1.8 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.25 ACL93557.1 - 0.029 13.8 0.1 0.059 12.8 0.1 1.6 1 1 0 1 1 1 0 short chain dehydrogenase NAD_binding_8 PF13450.6 ACL93557.1 - 0.089 13.0 0.7 1.3 9.4 0.1 2.7 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain KR PF08659.10 ACL93557.1 - 0.11 12.4 0.2 0.93 9.4 0.1 2.1 1 1 1 2 2 2 0 KR domain UDPG_MGDP_dh_N PF03721.14 ACL93557.1 - 0.13 11.9 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain EamA PF00892.20 ACL93558.1 - 1.1e-29 103.4 26.9 6.2e-17 62.1 12.4 2.0 2 0 0 2 2 2 2 EamA-like transporter family DUF2070 PF09843.9 ACL93558.1 - 0.41 8.9 7.1 0.12 10.6 4.4 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) adh_short_C2 PF13561.6 ACL93559.1 - 4.8e-61 206.3 0.1 6.8e-61 205.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ACL93559.1 - 4.5e-50 169.8 0.1 1.4e-49 168.3 0.1 1.7 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.10 ACL93559.1 - 4.3e-07 30.0 0.3 2.2e-06 27.7 0.2 2.0 2 1 0 2 2 2 1 KR domain Glyco_tran_WecB PF03808.13 ACL93561.1 - 9.3e-49 165.6 0.2 1.6e-48 164.8 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase WecB/TagA/CpsF family Peripla_BP_6 PF13458.6 ACL93561.1 - 0.00067 19.4 0.2 0.001 18.8 0.2 1.3 1 0 0 1 1 1 1 Periplasmic binding protein ADH_zinc_N PF00107.26 ACL93562.1 - 3e-21 75.8 0.1 4.7e-21 75.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ACL93562.1 - 4.8e-18 66.5 0.0 1.3e-17 65.1 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ACL93562.1 - 2.4e-13 49.9 0.0 5e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 ACL93562.1 - 0.0026 17.3 0.3 0.0036 16.8 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase ADH_N_2 PF16884.5 ACL93562.1 - 0.0043 16.9 0.1 0.016 15.1 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase 2-Hacid_dh_C PF02826.19 ACL93562.1 - 0.082 12.3 0.3 0.15 11.4 0.3 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Asparaginase_2 PF01112.18 ACL93563.1 - 4.3e-78 262.4 15.9 6.5e-77 258.6 15.9 1.9 1 1 0 1 1 1 1 Asparaginase DinB_2 PF12867.7 ACL93565.1 - 0.041 14.4 0.4 0.055 14.0 0.4 1.1 1 0 0 1 1 1 0 DinB superfamily RecX PF02631.16 ACL93565.1 - 0.049 14.1 0.0 0.062 13.8 0.0 1.2 1 0 0 1 1 1 0 RecX family Hepar_II_III PF07940.13 ACL93566.1 - 5.4e-46 157.1 0.1 7.7e-46 156.6 0.1 1.2 1 0 0 1 1 1 1 Heparinase II/III-like protein Ribul_P_3_epim PF00834.19 ACL93567.2 - 5.2e-82 274.0 0.0 5.9e-82 273.9 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family ADH_zinc_N PF00107.26 ACL93567.2 - 0.014 15.4 0.2 0.084 12.9 0.2 2.2 1 1 0 1 1 1 0 Zinc-binding dehydrogenase PGM_PMM_II PF02879.16 ACL93567.2 - 0.021 15.4 0.0 7.7 7.2 0.0 2.4 1 1 1 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PEP_mutase PF13714.6 ACL93567.2 - 0.025 14.0 0.1 0.73 9.2 0.0 2.5 1 1 2 3 3 3 0 Phosphoenolpyruvate phosphomutase DHO_dh PF01180.21 ACL93567.2 - 0.06 12.5 0.3 0.19 10.9 0.1 1.8 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Methyltr_RsmB-F PF01189.17 ACL93568.1 - 2.4e-53 180.8 0.0 3.4e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F NusB PF01029.18 ACL93568.1 - 6.3e-16 58.8 0.0 9.5e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 NusB family Methyltransf_25 PF13649.6 ACL93568.1 - 1.1e-07 32.5 0.1 3.5e-07 30.8 0.1 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ACL93568.1 - 7.3e-06 25.8 0.0 1.1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ACL93568.1 - 0.00011 21.9 0.0 0.00069 19.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_11 PF08241.12 ACL93568.1 - 0.0023 18.5 0.1 0.0077 16.9 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 ACL93568.1 - 0.0053 16.3 0.0 0.0073 15.9 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 ACL93568.1 - 0.0084 15.8 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 adh_short PF00106.25 ACL93568.1 - 0.016 14.7 0.1 0.031 13.7 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase FtsJ PF01728.19 ACL93568.1 - 0.016 15.3 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 ACL93568.1 - 0.036 13.9 0.0 0.21 11.4 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain DUF1674 PF07896.12 ACL93569.2 - 1.7e-13 50.8 1.4 1.7e-13 50.8 1.4 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1674) G_glu_transpept PF01019.21 ACL93570.1 - 8.5e-172 572.5 0.1 9.8e-172 572.3 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase OMPdecase PF00215.24 ACL93571.1 - 2.3e-41 141.9 0.0 2.6e-41 141.7 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family AAA_33 PF13671.6 ACL93571.1 - 0.085 13.0 0.2 0.37 11.0 0.2 2.0 1 1 1 2 2 2 0 AAA domain MarC PF01914.17 ACL93572.1 - 2.1e-43 148.1 13.0 2.5e-43 147.8 13.0 1.0 1 0 0 1 1 1 1 MarC family integral membrane protein FAD_binding_3 PF01494.19 ACL93573.1 - 7.3e-23 81.4 0.0 6.5e-22 78.2 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 ACL93573.1 - 8.8e-07 28.3 2.2 0.24 10.4 0.5 3.1 3 0 0 3 3 3 3 Lycopene cyclase protein SE PF08491.10 ACL93573.1 - 2.3e-05 23.6 0.0 3.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_2 PF00890.24 ACL93573.1 - 0.00061 19.0 0.5 0.0028 16.8 0.2 2.2 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.14 ACL93573.1 - 0.003 16.8 0.0 0.11 11.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ACL93573.1 - 0.078 13.2 0.1 0.32 11.3 0.1 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 ACL93573.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 ACL93573.1 - 0.16 11.3 0.3 0.19 11.0 0.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trm112p PF03966.16 ACL93574.1 - 2.3e-11 44.1 0.0 3.6e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Trm112p-like protein LON_substr_bdg PF02190.16 ACL93575.1 - 1.4e-22 80.6 0.0 2.6e-22 79.7 0.0 1.4 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain GRIP PF01465.20 ACL93575.1 - 0.13 12.2 0.1 0.34 10.8 0.0 1.8 1 1 0 1 1 1 0 GRIP domain TPR_20 PF14561.6 ACL93576.1 - 1.2e-31 108.9 9.4 3.8e-30 104.0 2.3 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat Thioredoxin PF00085.20 ACL93576.1 - 9.1e-26 89.8 0.0 1.5e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin TPR_19 PF14559.6 ACL93576.1 - 1.9e-14 53.9 17.3 4e-10 40.1 5.9 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat Thioredoxin_2 PF13098.6 ACL93576.1 - 1.1e-08 35.4 0.0 2.6e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain TPR_17 PF13431.6 ACL93576.1 - 2.7e-08 33.6 0.2 0.0012 19.1 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 ACL93576.1 - 3.5e-08 34.0 24.1 9.1e-05 23.0 3.7 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 ACL93576.1 - 8.4e-08 32.4 21.8 0.037 14.8 4.0 4.7 1 1 2 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 ACL93576.1 - 3.6e-06 26.7 5.4 0.079 13.1 0.0 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat Thioredoxin_8 PF13905.6 ACL93576.1 - 8e-06 26.1 0.0 2.3e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like TPR_11 PF13414.6 ACL93576.1 - 5.9e-05 22.7 4.6 0.00053 19.6 0.2 2.7 3 0 0 3 3 3 1 TPR repeat TPR_1 PF00515.28 ACL93576.1 - 0.00024 20.8 0.2 1.6 8.6 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat Thioredoxin_7 PF13899.6 ACL93576.1 - 0.00042 20.4 0.0 0.001 19.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 ACL93576.1 - 0.00043 20.2 0.0 0.00074 19.4 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ACL93576.1 - 0.00043 20.0 0.4 0.0011 18.6 0.0 1.9 3 0 0 3 3 2 1 Redoxin OST3_OST6 PF04756.13 ACL93576.1 - 0.0052 16.2 0.0 0.0072 15.7 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family TPR_9 PF13371.6 ACL93576.1 - 0.0066 16.6 15.4 0.053 13.7 6.7 2.9 1 1 2 3 3 3 1 Tetratricopeptide repeat Thioredoxin_3 PF13192.6 ACL93576.1 - 0.0091 16.0 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain Alkyl_sulf_dimr PF14863.6 ACL93576.1 - 0.033 14.7 3.1 3.7 8.0 0.1 2.5 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation TraF PF13728.6 ACL93576.1 - 0.06 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 ACL93576.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin TPR_4 PF07721.14 ACL93576.1 - 0.12 13.1 0.2 0.12 13.1 0.2 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF953 PF06110.11 ACL93576.1 - 0.12 12.0 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) TPR_8 PF13181.6 ACL93576.1 - 0.17 12.2 1.9 6.8 7.2 0.0 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat HEAT_2 PF13646.6 ACL93576.1 - 0.35 11.3 9.3 0.77 10.2 9.3 1.6 1 0 0 1 1 1 0 HEAT repeats TPR_12 PF13424.6 ACL93576.1 - 3.4 8.0 10.5 1.8 8.9 0.2 3.5 3 1 1 4 4 3 0 Tetratricopeptide repeat tRNA_edit PF04073.15 ACL93577.1 - 1.8e-26 92.6 0.0 2.2e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain MlaD PF02470.20 ACL93577.1 - 0.11 12.8 0.0 0.31 11.3 0.0 1.7 2 0 0 2 2 2 0 MlaD protein Glyoxalase PF00903.25 ACL93579.1 - 0.0057 16.8 0.0 0.14 12.3 0.0 2.0 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Phage_holin_3_6 PF07332.11 ACL93580.1 - 0.028 14.5 0.7 0.028 14.5 0.7 3.0 1 1 2 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III HTH_34 PF13601.6 ACL93581.1 - 3e-26 91.4 0.0 3.5e-26 91.2 0.0 1.0 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_5 PF01022.20 ACL93581.1 - 1.1e-05 25.2 0.0 1.5e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 ACL93581.1 - 5.6e-05 23.1 0.0 9.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain PadR PF03551.14 ACL93581.1 - 0.00044 20.2 0.0 0.00061 19.7 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family PD40 PF07676.12 ACL93582.2 - 4.4e-42 141.2 16.5 1.8e-10 40.5 0.2 9.6 10 0 0 10 10 10 7 WD40-like Beta Propeller Repeat Amidohydro_1 PF01979.20 ACL93582.2 - 1.9e-16 60.3 0.1 6.8e-16 58.5 0.1 1.9 1 1 0 1 1 1 1 Amidohydrolase family DPPIV_N PF00930.21 ACL93582.2 - 1.1e-12 47.4 0.0 0.0023 16.7 0.0 5.8 4 2 2 6 6 6 4 Dipeptidyl peptidase IV (DPP IV) N-terminal region Amidohydro_3 PF07969.11 ACL93582.2 - 2.3e-08 34.0 11.4 0.00016 21.3 0.2 3.7 3 1 1 4 4 4 2 Amidohydrolase family PGM_PMM_I PF02878.16 ACL93583.1 - 9e-43 145.3 0.0 7.4e-42 142.3 0.0 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 ACL93583.1 - 2e-33 114.9 0.2 3.7e-33 114.1 0.2 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 ACL93583.1 - 1.1e-21 77.3 0.0 2.8e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 ACL93583.1 - 2.3e-14 53.3 0.5 7.5e-14 51.7 0.3 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain SIS PF01380.22 ACL93584.1 - 9.5e-52 174.3 1.4 1.1e-27 96.4 0.2 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 ACL93584.1 - 4.6e-23 81.9 0.1 1e-22 80.8 0.1 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 ACL93584.1 - 3.5e-14 52.8 0.0 8e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain SIS_2 PF13580.6 ACL93584.1 - 0.0018 18.3 0.2 0.073 13.1 0.0 2.6 2 1 0 2 2 2 1 SIS domain GATase_4 PF13230.6 ACL93584.1 - 0.0056 15.6 0.0 0.0096 14.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II DUF533 PF04391.12 ACL93584.1 - 0.007 16.0 1.0 0.015 14.8 1.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF533) PK_C PF02887.16 ACL93584.1 - 0.019 15.2 0.9 0.21 11.8 0.4 2.6 3 0 0 3 3 3 0 Pyruvate kinase, alpha/beta domain Ligase_CoA PF00549.19 ACL93584.1 - 0.052 13.4 0.2 0.17 11.7 0.1 1.9 2 0 0 2 2 2 0 CoA-ligase Glyco_transf_41 PF13844.6 ACL93585.1 - 6.1e-44 150.2 0.0 3.9e-24 84.9 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 41 TPR_1 PF00515.28 ACL93585.1 - 1.5e-35 119.5 7.6 5.6e-08 32.3 0.0 7.6 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 ACL93585.1 - 1.1e-33 112.6 1.8 1.6e-05 24.7 0.0 7.3 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 ACL93585.1 - 6.7e-33 110.1 22.4 4.5e-07 29.5 0.0 8.8 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.6 ACL93585.1 - 6.6e-27 93.9 47.9 1.9e-11 44.4 0.4 6.6 2 1 5 8 8 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 ACL93585.1 - 1.3e-26 91.9 10.6 9.5e-09 34.8 0.0 6.7 4 2 3 7 7 7 5 TPR repeat TPR_14 PF13428.6 ACL93585.1 - 2.5e-25 87.0 37.1 0.00027 21.5 1.9 9.9 4 3 5 9 9 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 ACL93585.1 - 7.5e-25 87.2 32.1 1.3e-07 32.0 2.4 6.6 2 2 5 7 7 7 7 Tetratricopeptide repeat TPR_17 PF13431.6 ACL93585.1 - 4.9e-20 70.4 16.8 4.8e-05 23.5 0.1 7.5 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 ACL93585.1 - 7.7e-18 64.6 22.5 2.2e-05 24.6 1.2 6.2 2 2 4 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 ACL93585.1 - 2.6e-11 42.7 11.4 0.0021 17.9 0.0 6.7 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 ACL93585.1 - 6.3e-10 38.6 29.5 0.04 13.8 0.1 7.9 9 0 0 9 9 7 4 Tetratricopeptide repeat TPR_4 PF07721.14 ACL93585.1 - 3.6e-07 30.2 30.1 1.4 9.8 0.1 9.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 ACL93585.1 - 6.3e-07 29.5 20.2 0.01 16.0 0.3 5.2 1 1 5 7 7 7 4 Tetratricopeptide repeat TPR_15 PF13429.6 ACL93585.1 - 3.2e-05 23.3 10.1 0.0016 17.7 2.0 4.0 2 2 1 3 3 3 2 Tetratricopeptide repeat Coatomer_E PF04733.14 ACL93585.1 - 6.9e-05 22.4 2.8 1.8 7.9 0.2 4.5 3 1 2 5 5 5 1 Coatomer epsilon subunit NARP1 PF12569.8 ACL93585.1 - 0.01 14.8 0.9 2.9 6.7 0.4 2.9 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 Wzy_C_2 PF11846.8 ACL93585.1 - 0.013 15.4 4.9 0.72 9.7 0.0 3.7 2 2 1 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal ANAPC3 PF12895.7 ACL93585.1 - 0.5 10.6 7.6 2.2 8.6 0.9 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 LTXXQ PF07813.12 ACL93585.1 - 0.5 11.1 0.1 0.5 11.1 0.1 2.3 3 0 0 3 3 2 0 LTXXQ motif family protein BTAD PF03704.17 ACL93585.1 - 0.97 9.9 16.6 6.2 7.2 3.7 4.7 1 1 4 5 5 5 0 Bacterial transcriptional activator domain TrmO PF01980.16 ACL93586.1 - 5.2e-27 94.4 0.0 6.4e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 tRNA-methyltransferase O Acetyltransf_1 PF00583.25 ACL93587.1 - 9.9e-05 22.6 0.0 0.00014 22.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family PrsW-protease PF13367.6 ACL93587.1 - 0.042 13.3 0.7 0.062 12.7 0.3 1.5 2 0 0 2 2 2 0 PrsW family intramembrane metalloprotease Lumazine_bd_2 PF12893.7 ACL93588.1 - 2.3e-05 25.0 0.2 0.00049 20.8 0.2 2.1 1 1 0 1 1 1 1 Putative lumazine-binding DUF4440 PF14534.6 ACL93588.1 - 0.0013 19.1 0.1 0.002 18.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) DUF1232 PF06803.12 ACL93589.1 - 2e-14 53.1 4.9 3.4e-14 52.3 4.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1232) DUF3563 PF12086.8 ACL93589.1 - 0.16 11.7 0.1 0.28 10.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3563) adh_short PF00106.25 ACL93590.1 - 1.1e-45 155.5 1.9 1.4e-45 155.1 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ACL93590.1 - 1.6e-44 152.2 0.8 2e-44 151.9 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ACL93590.1 - 0.0043 16.5 0.5 0.0063 16.0 0.5 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_8 PF13450.6 ACL93590.1 - 0.014 15.6 0.2 0.03 14.6 0.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain KR PF08659.10 ACL93590.1 - 0.016 15.1 7.2 0.17 11.8 2.8 2.8 2 2 0 2 2 2 0 KR domain LysE PF01810.18 ACL93592.1 - 1.9e-30 105.8 12.2 2.2e-30 105.5 12.2 1.0 1 0 0 1 1 1 1 LysE type translocator TerC PF03741.16 ACL93592.1 - 1.3 8.7 6.9 0.072 12.8 1.7 1.7 2 1 0 2 2 2 0 Integral membrane protein TerC family MAPEG PF01124.18 ACL93593.1 - 3.1e-20 72.4 8.4 3.7e-20 72.1 8.4 1.1 1 0 0 1 1 1 1 MAPEG family KTSC PF13619.6 ACL93594.1 - 2.2e-19 69.0 0.3 2.5e-19 68.9 0.3 1.0 1 0 0 1 1 1 1 KTSC domain Arginosuc_synth PF00764.19 ACL93595.1 - 3e-154 514.0 0.0 3.5e-154 513.8 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 ACL93595.1 - 0.0007 19.1 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 ACL93595.1 - 0.0094 15.7 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase UvrD_C_2 PF13538.6 ACL93596.1 - 0.068 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain K_trans PF02705.16 ACL93597.1 - 1.2e-197 657.6 19.9 1.4e-197 657.4 19.9 1.0 1 0 0 1 1 1 1 K+ potassium transporter S_2TMBeta PF18153.1 ACL93597.1 - 0.47 10.2 2.1 1 9.1 2.1 1.5 1 0 0 1 1 1 0 SMODS-associating 2TM, beta-strand rich effector domain Phage_holin_2_3 PF16080.5 ACL93597.1 - 9.8 6.0 6.5 16 5.3 0.3 3.5 3 0 0 3 3 3 0 Bacteriophage holin family HP1 Rrf2 PF02082.20 ACL93598.1 - 1.2e-22 80.1 0.2 2.3e-22 79.1 0.0 1.5 2 0 0 2 2 2 1 Transcriptional regulator HrcA_DNA-bdg PF03444.15 ACL93598.1 - 0.0073 15.9 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding adh_short PF00106.25 ACL93599.1 - 1.3e-42 145.5 0.1 1.6e-42 145.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ACL93599.1 - 1.3e-28 100.1 0.6 1.7e-28 99.8 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ACL93599.1 - 2.7e-09 37.2 0.4 3.8e-09 36.7 0.4 1.2 1 0 0 1 1 1 1 KR domain Radical_SAM PF04055.21 ACL93600.1 - 9.4e-20 71.7 0.0 1.6e-19 70.9 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 ACL93600.1 - 2.7e-05 24.3 0.0 5.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 ACL93600.1 - 0.063 13.6 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain GPP34 PF05719.11 ACL93600.1 - 0.077 13.0 0.1 0.24 11.4 0.1 1.9 2 0 0 2 2 2 0 Golgi phosphoprotein 3 (GPP34) DUF350 PF03994.14 ACL93601.1 - 1.5e-23 82.7 16.4 1.3e-11 44.4 3.5 2.1 2 0 0 2 2 2 2 Domain of Unknown Function (DUF350) Trypsin_2 PF13365.6 ACL93602.1 - 1.4e-16 61.8 4.9 1.4e-16 61.8 4.9 2.0 2 0 0 2 2 2 1 Trypsin-like peptidase domain Peptidase_S32 PF05579.13 ACL93602.1 - 8.9e-05 21.8 0.3 0.04 13.1 0.1 2.2 2 0 0 2 2 2 2 Equine arteritis virus serine endopeptidase S32 MFS_1 PF07690.16 ACL93603.1 - 5.9e-18 64.9 57.3 2.1e-16 59.8 46.8 3.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Acatn PF13000.7 ACL93603.1 - 1.5e-10 40.3 6.6 8.4e-10 37.8 6.6 2.0 1 1 0 1 1 1 1 Acetyl-coenzyme A transporter 1 Response_reg PF00072.24 ACL93604.1 - 6.1e-29 100.5 0.0 1.9e-26 92.4 0.1 2.5 2 1 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 ACL93604.1 - 3.6e-23 82.2 0.0 5.3e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ACL93604.1 - 5.9e-17 61.5 0.8 2.5e-16 59.5 0.4 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HTH_32 PF13565.6 ACL93604.1 - 0.45 11.2 3.0 8.9 7.0 0.1 3.6 4 0 0 4 4 4 0 Homeodomain-like domain TonB_dep_Rec PF00593.24 ACL93605.1 - 7.5e-38 131.6 9.8 9.9e-38 131.2 9.8 1.1 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 ACL93605.1 - 3e-15 56.7 0.0 8.1e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 ACL93605.1 - 0.0026 16.8 0.0 0.0052 15.8 0.0 1.5 1 0 0 1 1 1 1 Outer membrane protein beta-barrel family Mg_chelatase PF01078.21 ACL93606.1 - 3.6e-93 310.7 0.1 5.3e-93 310.1 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ChlI PF13541.6 ACL93606.1 - 3e-34 117.5 0.0 4.6e-34 116.9 0.0 1.3 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Mg_chelatase_C PF13335.6 ACL93606.1 - 6.7e-26 90.8 3.8 1.9e-25 89.3 3.8 1.8 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI C-terminal MCM PF00493.23 ACL93606.1 - 9.4e-08 31.4 0.0 2.2e-06 27.0 0.0 2.2 1 1 0 1 1 1 1 MCM P-loop domain AAA_5 PF07728.14 ACL93606.1 - 1.4e-07 31.6 0.0 8.1e-07 29.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 ACL93606.1 - 4.4e-07 29.7 0.0 2.7e-06 27.2 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_33 PF13671.6 ACL93606.1 - 0.00068 19.8 0.0 0.0016 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ACL93606.1 - 0.0031 17.9 0.5 0.0088 16.4 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ACL93606.1 - 0.0033 17.7 0.0 0.0065 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 ACL93606.1 - 0.0044 17.5 0.0 0.013 15.9 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_32 PF13654.6 ACL93606.1 - 0.011 14.6 0.0 0.11 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ACL93606.1 - 0.028 13.9 0.0 0.1 12.1 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 ACL93606.1 - 0.058 13.5 0.0 0.79 9.8 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain RuvB_N PF05496.12 ACL93606.1 - 0.068 12.9 0.0 0.35 10.6 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 ACL93606.1 - 0.099 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 ACL93606.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 ACL93606.1 - 0.18 12.3 0.0 0.35 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ACL93606.1 - 0.18 11.7 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_2 PF07724.14 ACL93606.1 - 0.2 11.8 0.0 3 7.9 0.0 2.4 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) GSH-S_ATP PF02955.16 ACL93607.1 - 5.5e-70 234.3 0.0 1.3e-69 233.1 0.0 1.6 2 0 0 2 2 2 1 Prokaryotic glutathione synthetase, ATP-grasp domain GSH-S_N PF02951.14 ACL93607.1 - 1.2e-41 141.5 0.3 1.8e-41 141.0 0.3 1.3 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, N-terminal domain RimK PF08443.11 ACL93607.1 - 3.1e-14 53.0 0.0 4.6e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATPgrasp_YheCD PF14398.6 ACL93607.1 - 0.00031 20.1 0.0 0.0039 16.5 0.0 2.3 1 1 0 1 1 1 1 YheC/D like ATP-grasp GSP_synth PF03738.14 ACL93607.1 - 0.14 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Glutathionylspermidine synthase preATP-grasp Transglut_core2 PF13369.6 ACL93608.1 - 6.1e-32 110.3 0.1 1e-31 109.6 0.1 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily TPR_9 PF13371.6 ACL93608.1 - 1.9e-11 43.9 10.1 1.9e-11 43.9 10.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat UPF0102 PF02021.17 ACL93609.1 - 1.4e-17 63.7 0.1 1.7e-17 63.4 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0102 NucS PF01939.16 ACL93609.1 - 0.0096 15.3 0.1 0.011 15.1 0.1 1.1 1 0 0 1 1 1 1 Endonuclease NucS HSDR_N PF04313.14 ACL93609.1 - 0.036 14.0 0.0 0.049 13.6 0.0 1.2 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) NERD PF08378.11 ACL93609.1 - 0.039 14.4 0.0 0.048 14.1 0.0 1.1 1 0 0 1 1 1 0 Nuclease-related domain Hjc PF01870.18 ACL93609.1 - 0.082 12.9 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Archaeal holliday junction resolvase (hjc) DUF4143 PF13635.6 ACL93609.1 - 0.22 11.7 0.0 0.29 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4143) TP_methylase PF00590.20 ACL93610.1 - 8.9e-31 107.5 1.4 1.6e-30 106.7 1.4 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases PhageMin_Tail PF10145.9 ACL93610.1 - 0.031 14.1 0.3 0.085 12.7 0.1 1.8 3 0 0 3 3 3 0 Phage-related minor tail protein Hpt PF01627.23 ACL93610.1 - 0.043 14.1 0.1 0.11 12.8 0.0 1.9 1 1 0 1 1 1 0 Hpt domain HTH_7 PF02796.15 ACL93610.1 - 0.053 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Radical_SAM PF04055.21 ACL93611.1 - 3e-17 63.5 0.0 5e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily HemN_C PF06969.16 ACL93611.1 - 5.4e-10 39.2 0.6 1.3e-09 37.9 0.3 1.9 2 0 0 2 2 2 1 HemN C-terminal domain TetR_C_7 PF14246.6 ACL93611.1 - 0.029 14.4 0.3 16 5.6 0.0 3.3 2 1 1 3 3 3 0 AefR-like transcriptional repressor, C-terminal domain Ham1p_like PF01725.16 ACL93612.1 - 5.6e-57 192.7 0.0 6.2e-57 192.5 0.0 1.0 1 0 0 1 1 1 1 Ham1 family GST_N_3 PF13417.6 ACL93613.1 - 4.2e-15 55.9 0.0 9.1e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ACL93613.1 - 4.5e-11 42.9 0.0 7.9e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ACL93613.1 - 2.5e-05 24.2 2.0 4.9e-05 23.3 2.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ACL93613.1 - 2.6e-05 24.5 0.0 4.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ACL93613.1 - 0.029 14.6 0.1 0.077 13.2 0.1 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF4229 PF14012.6 ACL93614.2 - 0.025 14.7 2.2 0.025 14.6 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) DUF751 PF05421.11 ACL93614.2 - 0.06 14.1 0.8 0.06 14.1 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF751) DUF2975 PF11188.8 ACL93615.1 - 2.7e-13 50.0 1.1 2.7e-13 50.0 1.1 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF2975) HTH_26 PF13443.6 ACL93616.1 - 2.3e-18 66.4 0.1 2.7e-18 66.1 0.1 1.0 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_31 PF13560.6 ACL93616.1 - 0.00055 20.2 0.2 0.0007 19.9 0.2 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 ACL93616.1 - 0.0024 17.9 0.0 0.0027 17.7 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 ACL93616.1 - 0.004 17.2 0.0 0.0047 17.0 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_37 PF13744.6 ACL93616.1 - 0.082 12.9 0.0 0.097 12.6 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain PDZ_2 PF13180.6 ACL93617.1 - 4.1e-14 52.7 0.0 7.2e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Trypsin_2 PF13365.6 ACL93617.1 - 4.8e-14 53.5 0.1 7.8e-14 52.8 0.1 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_6 PF17820.1 ACL93617.1 - 7.1e-11 41.8 0.1 1.4e-10 40.9 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 ACL93617.1 - 7e-07 29.5 0.0 1.1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 ACL93617.1 - 0.002 18.0 0.0 0.0054 16.7 0.0 1.7 1 0 0 1 1 1 1 Tricorn protease PDZ domain PDZ_1 PF12812.7 ACL93617.1 - 0.086 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 PDZ-like domain GRASP55_65 PF04495.14 ACL93617.1 - 0.11 12.9 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain RNase_PH PF01138.21 ACL93618.1 - 3.5e-23 82.6 0.0 5.5e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 ACL93618.1 - 1.6e-10 40.8 0.0 2.6e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 HrcA PF01628.21 ACL93619.1 - 6e-54 183.3 0.0 7.7e-54 182.9 0.0 1.1 1 0 0 1 1 1 1 HrcA protein C terminal domain HrcA_DNA-bdg PF03444.15 ACL93619.1 - 0.00023 20.7 0.0 0.00046 19.8 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding GrpE PF01025.19 ACL93620.1 - 3.6e-48 163.3 0.7 4.4e-48 163.1 0.7 1.0 1 0 0 1 1 1 1 GrpE ZapB PF06005.12 ACL93620.1 - 0.21 12.1 4.1 0.36 11.3 4.1 1.3 1 0 0 1 1 1 0 Cell division protein ZapB DUF2061 PF09834.9 ACL93621.1 - 5.8e-20 71.6 1.5 7e-20 71.3 1.5 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2061) PAP2_3 PF14378.6 ACL93621.1 - 0.065 12.9 2.0 0.085 12.5 2.0 1.2 1 0 0 1 1 1 0 PAP2 superfamily Ycf9 PF01737.17 ACL93621.1 - 0.082 12.8 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 YCF9 DNA_pol3_beta_2 PF02767.16 ACL93622.1 - 2.7e-45 153.3 0.0 5.3e-38 129.8 0.0 3.0 3 0 0 3 3 3 2 DNA polymerase III beta subunit, central domain DNA_pol3_beta PF00712.19 ACL93622.1 - 5.5e-43 146.0 0.0 5.2e-39 133.1 0.0 3.2 3 0 0 3 3 3 2 DNA polymerase III beta subunit, N-terminal domain DNA_pol3_beta_3 PF02768.15 ACL93622.1 - 1.8e-42 144.0 0.0 8.2e-40 135.4 0.0 2.6 2 0 0 2 2 2 2 DNA polymerase III beta subunit, C-terminal domain TylF PF05711.11 ACL93622.1 - 0.062 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) HTH_20 PF12840.7 ACL93623.3 - 1.5e-13 50.6 0.0 1.8e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 ACL93623.3 - 2.2e-05 24.2 0.0 3.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family DprA_WH PF17782.1 ACL93623.3 - 0.0016 18.5 0.0 0.0029 17.7 0.0 1.5 1 1 0 1 1 1 1 DprA winged helix domain MarR_2 PF12802.7 ACL93623.3 - 0.037 13.9 0.0 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.6 ACL93623.3 - 0.083 12.5 0.0 0.15 11.7 0.0 1.4 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding Glyoxalase PF00903.25 ACL93624.1 - 4.3e-05 23.7 0.0 0.00031 20.9 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ACL93624.1 - 0.024 15.4 0.0 0.039 14.7 0.0 1.4 1 1 0 1 1 1 0 Glyoxalase-like domain SMC_N PF02463.19 ACL93625.1 - 1.7e-15 57.1 0.0 2.6e-15 56.5 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ACL93625.1 - 3.7e-10 40.1 4.1 4.1e-05 23.6 0.2 2.4 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ACL93625.1 - 1.2e-05 25.9 0.0 1.9e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 ACL93625.1 - 0.00034 20.4 0.0 0.013 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 ACL93625.1 - 0.0036 17.0 0.0 0.0074 16.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 ACL93625.1 - 0.0068 16.9 1.1 0.028 14.9 0.5 2.1 2 0 0 2 2 2 1 ABC transporter SbcCD_C PF13558.6 ACL93625.1 - 0.0076 16.5 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 ACL93625.1 - 0.025 14.9 0.7 4.5 7.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 ACL93625.1 - 0.035 14.3 2.7 0.094 13.0 0.1 2.7 3 1 0 3 3 3 0 AAA domain AAA_13 PF13166.6 ACL93625.1 - 0.33 9.5 0.0 0.43 9.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ACL93625.1 - 0.44 10.9 0.1 0.44 10.9 0.1 3.1 2 1 0 2 2 2 0 AAA ATPase domain DNA_gyraseB PF00204.25 ACL93626.2 - 1.2e-56 190.9 0.0 2.4e-56 190.0 0.0 1.5 1 0 0 1 1 1 1 DNA gyrase B DNA_gyraseB_C PF00986.21 ACL93626.2 - 2e-28 98.4 0.1 4e-28 97.4 0.1 1.5 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 ACL93626.2 - 4.5e-21 75.5 0.2 8.8e-21 74.5 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 ACL93626.2 - 2.5e-18 66.2 0.0 1.2e-17 64.0 0.0 2.1 2 0 0 2 2 2 1 Toprim domain GyrB_insert PF18053.1 ACL93626.2 - 3e-05 24.0 0.2 0.26 11.1 0.0 2.4 2 0 0 2 2 2 2 DNA gyrase B subunit insert domain HATPase_c_3 PF13589.6 ACL93626.2 - 0.00021 21.1 0.1 0.00049 19.9 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AFT PF08731.11 ACL93626.2 - 0.017 15.5 0.0 0.04 14.3 0.0 1.6 1 0 0 1 1 1 0 Transcription factor AFT SCP1201-deam PF14428.6 ACL93626.2 - 0.17 11.7 0.0 1 9.2 0.0 2.1 2 0 0 2 2 2 0 SCP1.201-like deaminase dCache_1 PF02743.18 ACL93627.1 - 1e-10 41.8 0.0 1.7e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Cache domain MCPsignal PF00015.21 ACL93627.1 - 1.2e-10 41.5 3.2 2.1e-10 40.7 3.2 1.3 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain UreE_N PF02814.15 ACL93627.1 - 0.03 13.9 0.3 0.062 12.9 0.3 1.6 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain sCache_3_2 PF17203.4 ACL93627.1 - 0.072 13.2 0.4 1.6 8.9 0.0 2.8 2 1 1 3 3 3 0 Single cache domain 3 BBP2_2 PF10082.9 ACL93629.1 - 3.3e-124 414.6 13.7 3.7e-124 414.4 13.7 1.0 1 0 0 1 1 1 1 Putative beta-barrel porin 2 OMP_b-brl PF13505.6 ACL93629.1 - 0.0001 22.5 23.0 0.012 15.8 7.2 3.7 1 1 1 3 3 3 3 Outer membrane protein beta-barrel domain DUF560 PF04575.13 ACL93629.1 - 0.0052 16.3 4.2 0.023 14.1 0.6 2.3 1 1 0 2 2 2 1 Protein of unknown function (DUF560) Autotransporter PF03797.19 ACL93629.1 - 0.043 13.5 15.2 1.1 8.8 6.7 3.7 1 1 2 3 3 3 0 Autotransporter beta-domain BBP2 PF07642.11 ACL93629.1 - 0.045 12.9 9.2 0.065 12.4 0.5 2.7 2 1 1 3 3 3 0 Putative beta-barrel porin-2, OmpL-like. bbp2 AAA_31 PF13614.6 ACL93630.1 - 5.5e-14 52.5 0.0 2e-13 50.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain GNVR PF13807.6 ACL93630.1 - 4e-11 42.7 0.0 1.6e-10 40.8 0.0 2.1 1 0 0 1 1 1 1 G-rich domain on putative tyrosine kinase Wzz PF02706.15 ACL93630.1 - 1.4e-09 38.1 1.0 1.4e-09 38.1 1.0 2.8 3 1 0 3 3 3 1 Chain length determinant protein CbiA PF01656.23 ACL93630.1 - 2.6e-08 34.0 0.5 8.4e-08 32.3 0.0 2.1 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 ACL93630.1 - 1.6e-05 24.3 0.0 4.3e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 ATPase MipZ ParA PF10609.9 ACL93630.1 - 1.8e-05 24.3 0.1 4.1e-05 23.1 0.1 1.7 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase FTHFS PF01268.19 ACL93630.1 - 0.00093 17.5 0.1 0.00093 17.5 0.1 1.8 3 0 0 3 3 3 1 Formate--tetrahydrofolate ligase SRP54 PF00448.22 ACL93630.1 - 0.00097 18.8 0.1 0.0035 17.0 0.0 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 ACL93630.1 - 0.0017 17.9 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ CLP1_P PF16575.5 ACL93630.1 - 0.0019 18.0 0.0 0.0043 16.9 0.0 1.6 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Fer4_NifH PF00142.18 ACL93630.1 - 0.018 14.5 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Secretin PF00263.21 ACL93630.1 - 0.037 13.7 2.0 0.41 10.3 0.0 2.8 3 0 0 3 3 3 0 Bacterial type II and III secretion system protein NanE PF04131.14 ACL93630.1 - 0.099 11.8 0.0 0.3 10.3 0.0 1.8 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Csm1_N PF18504.1 ACL93630.1 - 0.86 10.0 7.8 0.62 10.4 3.3 3.1 2 0 0 2 2 2 0 Csm1 N-terminal domain bZIP_1 PF00170.21 ACL93630.1 - 3.3 7.9 6.0 1.9 8.6 0.0 3.2 3 0 0 3 3 3 0 bZIP transcription factor FlxA PF14282.6 ACL93630.1 - 6 6.9 16.5 0.37 10.8 0.3 2.7 1 1 1 2 2 2 0 FlxA-like protein Wzy_C PF04932.15 ACL93631.1 - 1.4e-15 57.2 5.7 1.4e-15 57.2 5.7 3.6 4 0 0 4 4 4 1 O-Antigen ligase Bac_transf PF02397.16 ACL93632.2 - 1.2e-59 201.1 0.0 1.3e-59 200.9 0.0 1.0 1 0 0 1 1 1 1 Bacterial sugar transferase Peptidase_C93 PF06035.11 ACL93633.1 - 1.5e-39 135.4 0.3 5.5e-38 130.3 0.6 2.1 2 0 0 2 2 2 1 Bacterial transglutaminase-like cysteine proteinase BTLCP Hs1pro-1_C PF07014.12 ACL93633.1 - 0.15 11.5 0.0 0.22 11.0 0.0 1.1 1 0 0 1 1 1 0 Hs1pro-1 protein C-terminus Metallophos PF00149.28 ACL93634.1 - 2.3e-12 47.9 0.1 3.5e-12 47.2 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Poly_export PF02563.16 ACL93635.2 - 2.4e-18 66.1 0.0 8.8e-18 64.3 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis/export protein SLBB PF10531.9 ACL93635.2 - 2.9e-11 43.0 0.1 7.3e-11 41.8 0.1 1.7 1 0 0 1 1 1 1 SLBB domain LPAM_2 PF13627.6 ACL93636.1 - 8.8 6.3 6.4 17 5.4 6.4 1.5 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site TonB_dep_Rec PF00593.24 ACL93637.1 - 1.2e-25 91.4 25.5 1.2e-25 91.4 25.5 3.3 1 1 1 3 3 3 1 TonB dependent receptor OMP_b-brl_3 PF14905.6 ACL93637.1 - 8.5e-16 57.9 7.7 2.2e-15 56.6 2.4 2.6 2 1 1 3 3 3 2 Outer membrane protein beta-barrel family Plug PF07715.15 ACL93637.1 - 3.1e-09 37.4 0.6 3e-08 34.2 0.3 2.5 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain OMP_b-brl PF13505.6 ACL93637.1 - 1.3 9.1 14.5 0.12 12.5 3.8 3.8 2 1 1 3 3 3 0 Outer membrane protein beta-barrel domain T2SSC PF11356.8 ACL93638.1 - 5.5e-19 68.5 0.6 5.5e-18 65.2 0.6 1.9 1 1 0 1 1 1 1 Type II secretion system protein C Secretin PF00263.21 ACL93639.1 - 1.6e-49 167.9 2.1 4.5e-49 166.3 2.1 1.9 1 0 0 1 1 1 1 Bacterial type II and III secretion system protein Secretin_N PF03958.17 ACL93639.1 - 8.4e-39 131.8 14.4 1e-15 57.9 1.1 3.8 3 0 0 3 3 3 3 Bacterial type II/III secretion system short domain T2SSE PF00437.20 ACL93640.1 - 1.4e-88 296.5 4.2 1.8e-88 296.2 4.2 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 ACL93640.1 - 0.00019 21.1 0.0 0.00049 19.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 ACL93640.1 - 0.00019 21.9 0.1 0.00052 20.4 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 ACL93640.1 - 0.00034 20.4 0.1 0.0006 19.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ACL93640.1 - 0.0012 19.2 0.2 0.0029 18.0 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ACL93640.1 - 0.0016 18.8 0.0 0.003 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 ACL93640.1 - 0.0017 18.9 0.1 0.0026 18.3 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ACL93640.1 - 0.0035 17.2 0.0 0.0051 16.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 ACL93640.1 - 0.0087 16.0 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 ACL93640.1 - 0.012 15.5 1.0 0.21 11.5 0.2 2.3 1 1 1 2 2 2 0 NTPase Rad17 PF03215.15 ACL93640.1 - 0.038 13.9 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_18 PF13238.6 ACL93640.1 - 0.064 13.8 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ACL93640.1 - 0.089 13.3 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter ResIII PF04851.15 ACL93640.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SRP54 PF00448.22 ACL93640.1 - 0.1 12.2 0.4 0.2 11.3 0.2 1.5 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain cobW PF02492.19 ACL93640.1 - 0.11 12.1 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain PhoH PF02562.16 ACL93640.1 - 0.11 11.9 0.1 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_7 PF12775.7 ACL93640.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 ACL93640.1 - 0.17 11.1 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin T2SSF PF00482.23 ACL93641.1 - 5.7e-55 184.6 19.4 2.6e-28 98.5 1.8 2.7 3 0 0 3 3 3 2 Type II secretion system (T2SS), protein F DUF2207 PF09972.9 ACL93641.1 - 1.6 7.4 2.8 0.9 8.2 0.5 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF2070 PF09843.9 ACL93641.1 - 7.7 4.7 9.0 0.29 9.4 3.3 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) T2SSG PF08334.11 ACL93642.1 - 1.7e-40 137.5 0.1 2e-40 137.2 0.1 1.1 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein G N_methyl PF07963.12 ACL93642.1 - 3.2e-09 35.9 4.0 4.7e-09 35.4 4.0 1.3 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif N_methyl PF07963.12 ACL93643.3 - 1.2e-07 31.0 5.9 1.9e-07 30.3 5.9 1.4 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif GspH PF12019.8 ACL93643.3 - 5.7e-07 29.9 1.7 9.8e-07 29.2 1.7 1.4 1 0 0 1 1 1 1 Type II transport protein GspH T2SSI PF02501.17 ACL93644.3 - 7.2e-19 67.7 0.6 1e-18 67.3 0.6 1.2 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein I N_methyl PF07963.12 ACL93644.3 - 2.2e-09 36.5 2.9 3.6e-09 35.8 2.9 1.4 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif DUF2583 PF10762.9 ACL93644.3 - 0.16 12.4 0.7 18 5.8 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2583) T2SSJ PF11612.8 ACL93645.1 - 2.7e-30 105.4 0.1 3.8e-30 104.9 0.1 1.2 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein J N_methyl PF07963.12 ACL93645.1 - 5.5e-07 28.9 5.6 9.1e-07 28.2 5.6 1.4 1 0 0 1 1 1 1 Prokaryotic N-terminal methylation motif DUF4148 PF13663.6 ACL93645.1 - 1.3 9.2 4.8 8.2 6.7 4.8 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4148) T2SSK PF03934.13 ACL93646.1 - 1.8e-73 247.4 0.0 2e-73 247.2 0.0 1.0 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein K HHH_3 PF12836.7 ACL93646.1 - 0.00026 21.2 0.0 0.0013 18.9 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif GspL_C PF12693.7 ACL93647.1 - 1.8e-33 115.6 0.7 1.2e-32 112.9 0.1 2.1 2 0 0 2 2 2 1 GspL periplasmic domain T2SSL PF05134.13 ACL93647.1 - 5.3e-21 75.0 0.8 1.3e-20 73.8 0.7 1.6 1 1 1 2 2 2 1 Type II secretion system (T2SS), protein L T2SSM PF04612.12 ACL93648.1 - 2e-33 115.7 6.4 2.2e-33 115.6 6.4 1.0 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein M T2SSN PF01203.19 ACL93649.1 - 7e-27 95.0 10.0 8.1e-27 94.8 10.0 1.0 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein N DiS_P_DiS PF06750.13 ACL93650.1 - 9.9e-23 80.1 0.4 1.7e-22 79.3 0.4 1.4 1 0 0 1 1 1 1 Bacterial Peptidase A24 N-terminal domain Peptidase_A24 PF01478.18 ACL93650.1 - 1.9e-19 70.0 8.5 1.9e-19 70.0 8.5 3.1 3 1 1 4 4 4 1 Type IV leader peptidase family DUF4235 PF14019.6 ACL93650.1 - 0.12 12.5 4.0 0.47 10.6 4.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4235) Phage_holin_2_4 PF16082.5 ACL93650.1 - 7.3 6.4 6.4 32 4.4 0.9 2.7 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like TonB_dep_Rec PF00593.24 ACL93652.1 - 4.3e-48 165.4 32.3 4.3e-48 165.4 32.3 2.1 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 ACL93652.1 - 4.1e-16 59.5 1.4 3.9e-15 56.4 1.4 2.8 3 0 0 3 3 3 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 ACL93652.1 - 0.00071 18.7 4.3 0.04 12.9 0.0 3.4 3 0 0 3 3 3 2 Outer membrane protein beta-barrel family Xan_ur_permease PF00860.20 ACL93653.1 - 8e-45 153.2 47.1 9.5e-45 152.9 47.1 1.0 1 0 0 1 1 1 1 Permease family NUP PF06516.11 ACL93654.2 - 7.2e-104 347.4 0.0 8.3e-104 347.2 0.0 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) ABC_tran PF00005.27 ACL93655.2 - 1.7e-32 112.8 0.0 2.6e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ACL93655.2 - 7.1e-14 52.3 0.4 1.5e-07 31.5 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ACL93655.2 - 0.00019 21.0 0.1 0.14 11.6 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF4162 PF13732.6 ACL93655.2 - 0.00098 19.8 0.0 0.0022 18.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) AAA_24 PF13479.6 ACL93655.2 - 0.0039 17.0 0.1 1.9 8.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 ACL93655.2 - 0.0069 16.9 0.2 0.011 16.2 0.2 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ACL93655.2 - 0.0072 16.3 0.1 0.019 14.9 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase DUF72 PF01904.18 ACL93655.2 - 0.009 16.1 0.0 0.02 15.0 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function DUF72 AAA_29 PF13555.6 ACL93655.2 - 0.0091 15.7 0.1 0.018 14.8 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 ACL93655.2 - 0.023 15.1 0.0 0.042 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 ACL93655.2 - 0.039 13.7 0.1 0.21 11.3 0.1 2.1 1 1 1 2 2 2 0 AAA domain SRP54 PF00448.22 ACL93655.2 - 0.079 12.6 0.0 0.54 9.9 0.0 2.1 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 ACL93655.2 - 0.081 13.0 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 ACL93655.2 - 0.11 12.8 0.0 1.6 9.2 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_15 PF13175.6 ACL93655.2 - 0.14 11.9 0.0 0.84 9.3 0.0 1.9 1 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 ACL93655.2 - 0.16 12.3 0.0 1.2 9.4 0.0 2.4 1 1 1 2 2 2 0 AAA domain KAP_NTPase PF07693.14 ACL93655.2 - 0.22 10.7 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain zf-CHCC PF10276.9 ACL93656.1 - 1.1e-18 66.9 1.5 2.2e-18 66.0 1.5 1.5 1 0 0 1 1 1 1 Zinc-finger domain 4HBT PF03061.22 ACL93657.2 - 2.1e-17 63.2 0.2 3e-17 62.7 0.2 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 ACL93657.2 - 0.0084 16.4 0.0 0.011 16.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily MaoC_dehydratas PF01575.19 ACL93657.2 - 0.018 14.6 0.1 0.031 13.8 0.1 1.5 1 1 0 1 1 1 0 MaoC like domain Acetyltransf_1 PF00583.25 ACL93658.1 - 1.5e-16 60.6 0.2 1.9e-16 60.4 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ACL93658.1 - 1.5e-12 47.8 0.0 2.7e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ACL93658.1 - 2e-11 43.9 0.0 2.6e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ACL93658.1 - 2.3e-07 30.7 0.0 1.2e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_6 PF13480.7 ACL93658.1 - 1.5e-06 28.4 1.1 2.1e-06 27.9 1.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ACL93658.1 - 0.002 18.2 0.0 0.0036 17.4 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 ACL93658.1 - 0.028 14.5 0.0 0.084 12.9 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain AMP-binding PF00501.28 ACL93659.1 - 4.9e-78 262.6 0.0 6.3e-78 262.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ACL93659.1 - 1.6e-11 45.0 0.3 3.2e-11 44.0 0.3 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Iso_dh PF00180.20 ACL93660.1 - 7.4e-122 406.8 0.0 8.4e-122 406.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ABM PF03992.16 ACL93661.1 - 3.6e-15 55.8 0.0 4.3e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Aconitase_C PF00694.19 ACL93662.1 - 9e-35 119.9 0.0 1.2e-34 119.5 0.0 1.2 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase PF00330.20 ACL93663.1 - 1.3e-160 535.5 0.0 1.4e-160 535.3 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Ribosomal_L19 PF01245.20 ACL93664.1 - 2e-47 159.7 0.5 2.3e-47 159.5 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L19 tRNA_m1G_MT PF01746.21 ACL93665.1 - 2.2e-49 167.8 0.0 2.8e-49 167.5 0.0 1.0 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase E1_FCCH PF16190.5 ACL93666.1 - 2.1e-26 91.9 1.4 2.1e-11 43.8 0.1 3.5 3 0 0 3 3 3 2 Ubiquitin-activating enzyme E1 FCCH domain Tad PF13400.6 ACL93666.1 - 2e-08 34.4 6.2 2e-08 34.4 6.2 2.3 2 0 0 2 2 2 1 Putative Flp pilus-assembly TadE/G-like TadE PF07811.12 ACL93666.1 - 6.6e-05 23.1 2.2 0.00014 22.1 2.2 1.6 1 0 0 1 1 1 1 TadE-like protein VWA PF00092.28 ACL93666.1 - 0.00016 22.0 0.0 0.0094 16.2 0.0 3.0 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 ACL93666.1 - 0.00017 22.2 0.7 0.025 15.2 0.0 3.5 3 1 0 3 3 3 1 von Willebrand factor type A domain DIOX_N PF14226.6 ACL93667.1 - 2.9e-20 73.2 0.0 4.3e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ACL93667.1 - 9e-18 64.6 0.0 1.6e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily OmpA PF00691.20 ACL93668.1 - 1.2e-19 70.4 0.0 1.9e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 OmpA family Gly-zipper_Omp PF13488.6 ACL93668.1 - 3.6e-12 46.1 28.9 5.1e-11 42.4 14.6 2.8 2 1 1 3 3 3 2 Glycine zipper Gly-zipper_YMGG PF13441.6 ACL93668.1 - 7.3e-12 44.8 16.8 7.3e-12 44.8 16.8 2.1 2 0 0 2 2 2 1 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.6 ACL93668.1 - 9.1e-06 25.4 14.1 0.011 15.5 1.3 2.8 2 1 0 2 2 2 2 Glycine-zipper domain Rick_17kDa_Anti PF05433.15 ACL93668.1 - 0.0003 20.6 19.6 0.0003 20.6 19.6 2.7 3 1 0 3 3 3 1 Glycine zipper 2TM domain YtxH PF12732.7 ACL93668.1 - 0.0017 18.8 0.6 0.0017 18.8 0.6 2.7 2 1 1 3 3 3 1 YtxH-like protein DUF533 PF04391.12 ACL93668.1 - 0.006 16.2 0.1 0.01 15.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF533) Peptidase_A8 PF01252.18 ACL93668.1 - 0.024 14.9 1.1 0.046 13.9 0.1 2.0 3 0 0 3 3 3 0 Signal peptidase (SPase) II MucB_RseB PF03888.14 ACL93668.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 MucB/RseB N-terminal domain TraT PF05818.12 ACL93668.1 - 0.35 10.5 4.3 0.54 9.9 4.3 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF456 PF04306.13 ACL93668.1 - 0.52 10.6 4.0 0.13 12.5 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF456) FA_desaturase PF00487.24 ACL93669.1 - 6.6e-27 95.0 11.6 6.6e-27 95.0 11.6 1.9 1 1 1 2 2 2 1 Fatty acid desaturase FA_hydroxylase PF04116.13 ACL93670.2 - 4e-22 79.0 15.9 7.7e-22 78.1 15.9 1.5 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Na_H_Exchanger PF00999.21 ACL93671.1 - 2.3e-62 211.0 49.2 3.1e-62 210.6 49.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 ACL93671.1 - 9e-24 84.0 0.2 4.7e-23 81.7 0.0 2.1 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_7 PF13241.6 ACL93671.1 - 0.02 15.3 0.0 0.12 12.8 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding ApbA PF02558.16 ACL93671.1 - 0.16 11.6 0.8 3.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 ACL93671.1 - 0.23 11.0 0.3 0.46 10.0 0.0 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 ACL93671.1 - 0.42 9.8 3.2 0.33 10.1 0.0 2.2 2 1 0 2 2 2 0 FAD binding domain Flavodoxin_2 PF02525.17 ACL93672.2 - 3.9e-45 154.0 0.1 4.6e-45 153.8 0.1 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 ACL93672.2 - 0.00031 20.5 0.1 0.00047 19.9 0.1 1.5 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.7 ACL93672.2 - 0.17 11.6 0.3 6.2 6.5 0.1 2.2 1 1 1 2 2 2 0 Flavodoxin CoA_trans PF01144.23 ACL93673.1 - 2.3e-77 259.3 0.4 2.6e-77 259.1 0.4 1.0 1 0 0 1 1 1 1 Coenzyme A transferase AbiEi_2 PF09952.9 ACL93673.1 - 0.051 13.8 0.0 0.25 11.6 0.0 1.9 1 1 1 2 2 2 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system CoA_trans PF01144.23 ACL93674.1 - 4.7e-44 150.4 0.2 5.2e-44 150.2 0.2 1.0 1 0 0 1 1 1 1 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 ACL93674.1 - 0.0014 18.5 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain DJ-1_PfpI PF01965.24 ACL93675.1 - 7.4e-17 61.6 0.0 3.6e-16 59.4 0.0 1.9 2 0 0 2 2 2 1 DJ-1/PfpI family PMT_2 PF13231.6 ACL93676.1 - 3.5e-25 89.1 15.4 3.5e-25 89.1 15.4 2.5 3 1 1 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT PF02366.18 ACL93676.1 - 2.1e-09 37.3 8.8 2.1e-09 37.3 8.8 2.7 1 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Wzy_C PF04932.15 ACL93676.1 - 0.44 10.2 0.0 0.44 10.2 0.0 3.4 2 1 0 3 3 3 0 O-Antigen ligase TonB_dep_Rec PF00593.24 ACL93677.2 - 1.5e-32 114.1 30.7 1.5e-32 114.1 30.7 2.5 1 1 2 3 3 3 1 TonB dependent receptor Plug PF07715.15 ACL93677.2 - 4.6e-17 62.5 3.3 1.2e-16 61.2 3.3 1.8 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 ACL93677.2 - 4.2e-07 29.3 12.9 3.7e-05 22.9 0.5 3.0 4 1 0 4 4 4 2 Outer membrane protein beta-barrel family Adenine_glyco PF03352.13 ACL93677.2 - 0.2 11.4 0.2 15 5.3 0.0 2.3 2 0 0 2 2 2 0 Methyladenine glycosylase PAD_porph PF04371.15 ACL93678.2 - 4.9e-106 354.6 0.0 5.5e-106 354.5 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase TetR_C_28 PF17937.1 ACL93678.2 - 0.65 10.5 4.1 13 6.3 0.0 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain CN_hydrolase PF00795.22 ACL93679.1 - 3.2e-52 177.5 0.0 3.6e-52 177.3 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Acetyltransf_3 PF13302.7 ACL93680.1 - 1.4e-31 110.0 0.2 1.6e-31 109.8 0.2 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ACL93680.1 - 1.7e-08 34.7 0.0 2.1e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family TonB_dep_Rec PF00593.24 ACL93681.2 - 1.1e-38 134.4 0.4 1.3e-38 134.1 0.4 1.1 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 ACL93681.2 - 1.2e-19 70.9 1.2 5.1e-19 68.8 0.9 2.2 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain SapC PF07277.11 ACL93682.1 - 1.3e-65 221.1 0.0 1.5e-65 220.8 0.0 1.0 1 0 0 1 1 1 1 SapC DsbC PF11412.8 ACL93684.3 - 6e-22 78.0 0.0 9.7e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 Disulphide bond corrector protein DsbC Thioredoxin_7 PF13899.6 ACL93684.3 - 1.6e-20 73.0 0.1 2.5e-20 72.4 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like DsbD PF02683.15 ACL93684.3 - 1.1e-09 38.5 15.1 1.1e-09 38.5 15.1 1.5 2 0 0 2 2 2 1 Cytochrome C biogenesis protein transmembrane region Thioredoxin PF00085.20 ACL93684.3 - 0.00046 20.1 0.0 0.00078 19.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredox_DsbH PF03190.15 ACL93684.3 - 0.0064 16.5 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_2 PF13098.6 ACL93684.3 - 0.0086 16.5 0.0 0.014 15.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain DUF1353 PF07087.11 ACL93685.2 - 4.3e-30 103.3 0.0 7.3e-30 102.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1353) AhpC-TSA PF00578.21 ACL93687.1 - 2.6e-16 59.7 0.0 3.8e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ACL93687.1 - 1.6e-14 53.8 0.0 2.2e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin CelD_N PF02927.14 ACL93687.1 - 0.01 16.7 0.1 0.023 15.6 0.1 1.6 2 0 0 2 2 2 1 Cellulase N-terminal ig-like domain Thioredoxin_2 PF13098.6 ACL93687.1 - 0.014 15.9 0.0 0.04 14.4 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain SCO1-SenC PF02630.14 ACL93687.1 - 0.018 14.9 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 SCO1/SenC GSHPx PF00255.19 ACL93687.1 - 0.019 14.5 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 Glutathione peroxidase LANC_like PF05147.13 ACL93688.2 - 0.17 10.4 0.0 0.2 10.2 0.0 1.1 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein PGI PF00342.19 ACL93689.1 - 1.2e-185 617.8 0.0 1.4e-185 617.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Abhydrolase_1 PF00561.20 ACL93690.1 - 4.4e-16 59.3 0.0 8.7e-15 55.0 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ACL93690.1 - 4.3e-15 56.9 8.8 3.5e-13 50.7 8.8 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ACL93690.1 - 3.7e-13 49.3 0.1 8.6e-13 48.1 0.1 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 ACL93690.1 - 0.00022 21.0 0.0 0.00034 20.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 ACL93690.1 - 0.00045 20.4 0.0 0.0007 19.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain DIM PF08194.12 ACL93690.1 - 0.01 16.0 0.3 0.039 14.2 0.1 2.0 2 0 0 2 2 2 0 DIM protein UPF0227 PF05728.12 ACL93690.1 - 0.016 15.2 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Esterase PF00756.20 ACL93690.1 - 0.032 13.9 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.25 ACL93690.1 - 0.044 13.7 0.0 0.063 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) DUF1749 PF08538.10 ACL93690.1 - 0.13 11.4 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Ndr PF03096.14 ACL93690.1 - 0.16 10.6 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 Ndr family OMP_b-brl_3 PF14905.6 ACL93691.1 - 2.4e-09 36.7 0.0 3.2e-08 33.0 0.0 2.3 1 1 1 2 2 2 2 Outer membrane protein beta-barrel family Plug PF07715.15 ACL93691.1 - 1e-05 26.1 0.6 2.9e-05 24.6 0.6 1.8 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain DUF4148 PF13663.6 ACL93691.1 - 1.6 8.9 9.7 3.1 8.0 9.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) YjhX_toxin PF09857.9 ACL93693.1 - 2.9e-42 142.5 0.0 3.2e-42 142.4 0.0 1.0 1 0 0 1 1 1 1 Putative toxin of bacterial toxin-antitoxin pair Mrr_N PF14338.6 ACL93693.1 - 0.14 12.3 0.1 0.43 10.7 0.1 2.0 1 1 0 1 1 1 0 Mrr N-terminal domain Cons_hypoth95 PF03602.15 ACL93694.1 - 4.1e-57 192.8 0.0 4.6e-57 192.6 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MethyltransfD12 PF02086.15 ACL93694.1 - 0.00053 19.8 0.0 0.51 10.0 0.0 2.1 2 0 0 2 2 2 2 D12 class N6 adenine-specific DNA methyltransferase MTS PF05175.14 ACL93694.1 - 0.0016 18.0 0.0 0.0022 17.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 ACL93694.1 - 0.015 14.7 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 ACL93694.1 - 0.065 12.9 0.0 2.8 7.6 0.0 2.1 1 1 1 2 2 2 0 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 ACL93694.1 - 0.25 11.0 0.0 2.9 7.5 0.0 2.0 2 0 0 2 2 2 0 DNA methylase DUF1211 PF06736.11 ACL93695.1 - 1.8e-22 79.6 1.1 1.8e-22 79.6 1.1 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF1211) PsaM PF07465.13 ACL93695.1 - 0.068 12.9 0.5 0.068 12.9 0.5 2.7 2 0 0 2 2 2 0 Photosystem I protein M (PsaM) GtrA PF04138.14 ACL93695.1 - 4.1 7.7 10.6 0.13 12.5 3.8 2.1 2 1 0 2 2 2 0 GtrA-like protein CPBP PF02517.16 ACL93696.1 - 2e-13 50.5 4.8 2e-13 50.5 4.8 3.2 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease DUF2070 PF09843.9 ACL93696.1 - 6.4 4.9 9.9 7.3 4.8 9.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) S4 PF01479.25 ACL93697.2 - 1.3e-13 50.4 0.1 2.8e-13 49.4 0.1 1.6 1 0 0 1 1 1 1 S4 domain PseudoU_synth_2 PF00849.22 ACL93697.2 - 1.1e-10 41.9 0.0 1.9e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4_2 PF13275.6 ACL93697.2 - 0.039 13.8 0.0 0.083 12.7 0.0 1.5 1 0 0 1 1 1 0 S4 domain MafB19-deam PF14437.6 ACL93698.2 - 1.1e-26 93.3 0.0 1.4e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 ACL93698.2 - 5.7e-26 90.3 0.1 7.2e-26 90.0 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.6 ACL93698.2 - 8.2e-05 22.7 0.7 0.0041 17.2 0.3 2.2 1 1 1 2 2 2 1 Bd3614-like deaminase SNAD4 PF18750.1 ACL93698.2 - 0.0018 18.3 0.0 0.0028 17.8 0.0 1.2 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 ACL93698.2 - 0.096 12.7 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 APOBEC2 Polysacc_synt_2 PF02719.15 ACL93700.1 - 2.2e-102 342.2 0.0 2.6e-102 342.0 0.0 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 ACL93700.1 - 7e-23 81.3 0.0 5.4e-22 78.4 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ACL93700.1 - 1.5e-16 60.3 0.0 1.5e-15 57.0 0.0 1.9 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ACL93700.1 - 1.2e-12 47.9 0.0 7.7e-11 42.0 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 ACL93700.1 - 3e-09 36.4 0.1 1.8e-07 30.5 0.1 2.5 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 ACL93700.1 - 3.6e-09 36.2 0.1 2.4e-08 33.5 0.0 2.1 1 1 1 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 ACL93700.1 - 4.3e-07 30.0 0.1 9.8e-07 28.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 ACL93700.1 - 6.8e-06 25.7 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ACL93700.1 - 8.6e-05 22.5 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 ACL93700.1 - 0.00037 20.1 0.1 0.00057 19.5 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family DegT_DnrJ_EryC1 PF01041.17 ACL93701.1 - 2.6e-124 415.2 0.0 2.9e-124 415.0 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 ACL93701.1 - 1e-08 34.8 0.0 1.4e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ACL93701.1 - 8.8e-05 21.9 0.1 0.00014 21.2 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 ACL93701.1 - 0.0009 17.9 0.1 0.0013 17.3 0.1 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 ACL93701.1 - 0.0023 16.9 0.0 0.0036 16.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DUF5029 PF16432.5 ACL93701.1 - 0.16 11.5 0.3 0.34 10.4 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5029) OKR_DC_1 PF01276.20 ACL93701.1 - 0.17 10.6 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain RHH_1 PF01402.21 ACL93703.1 - 0.014 15.3 0.2 10 6.3 0.0 3.5 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family HTH_23 PF13384.6 ACL93703.1 - 0.018 14.8 0.0 0.079 12.8 0.0 2.1 1 0 0 1 1 1 0 Homeodomain-like domain Response_reg PF00072.24 ACL93704.1 - 7.8e-27 93.7 0.1 1.1e-26 93.2 0.1 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 ACL93704.1 - 7.5e-22 77.2 0.0 1.5e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal HATPase_c PF02518.26 ACL93705.1 - 4.3e-22 78.7 0.0 8.1e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sensor_TM1 PF13755.6 ACL93705.1 - 3.5e-17 61.9 1.3 3.5e-17 61.9 1.3 2.2 2 0 0 2 2 1 1 Sensor N-terminal transmembrane domain HisKA PF00512.25 ACL93705.1 - 2.2e-13 50.0 1.4 7e-13 48.4 1.4 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 ACL93705.1 - 4.2e-08 33.4 2.0 1.4e-07 31.8 0.9 2.5 2 0 0 2 2 2 1 HAMP domain Stimulus_sens_1 PF13756.6 ACL93705.1 - 2.9e-05 24.6 5.6 5.2e-05 23.8 1.3 3.2 3 1 0 3 3 3 1 Stimulus-sensing domain HATPase_c_3 PF13589.6 ACL93705.1 - 9.9e-05 22.2 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 ACL93705.1 - 0.0013 18.7 0.3 0.0052 16.7 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain DUF2797 PF10977.8 ACL93705.1 - 0.014 15.3 0.1 0.084 12.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2797) Baculo_PEP_C PF04513.12 ACL93705.1 - 0.03 14.4 0.3 0.091 12.8 0.3 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 ACL93705.1 - 0.07 12.0 0.1 0.13 11.1 0.1 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein HATPase_c_5 PF14501.6 ACL93705.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 GHKL domain CK2S PF15011.6 ACL93705.1 - 0.2 11.5 0.4 0.63 9.9 0.4 1.9 1 1 0 1 1 1 0 Casein Kinase 2 substrate Hpr_kinase_C PF07475.12 ACL93706.1 - 7.7e-17 61.3 0.1 1e-16 60.9 0.1 1.3 1 1 0 1 1 1 1 HPr Serine kinase C-terminal domain AAA_16 PF13191.6 ACL93706.1 - 0.11 12.8 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 ACL93706.1 - 0.12 12.5 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ACL93706.1 - 0.19 11.5 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain EIIA-man PF03610.16 ACL93707.1 - 1.6e-31 108.9 0.3 1.9e-31 108.7 0.3 1.0 1 0 0 1 1 1 1 PTS system fructose IIA component PTS-HPr PF00381.19 ACL93708.1 - 2.7e-28 98.0 0.9 3e-28 97.9 0.9 1.0 1 0 0 1 1 1 1 PTS HPr component phosphorylation site HAD_2 PF13419.6 ACL93711.1 - 2.6e-09 37.4 0.0 4.4e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ACL93711.1 - 4.5e-06 27.1 0.1 7.3e-06 26.4 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase LcrG PF07216.12 ACL93711.1 - 0.054 13.4 0.0 1.1 9.2 0.0 2.3 1 1 1 2 2 2 0 LcrG protein Pterin_4a PF01329.19 ACL93712.1 - 9.1e-29 99.5 0.1 1e-28 99.3 0.1 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase adh_short_C2 PF13561.6 ACL93713.1 - 8.4e-61 205.5 1.9 9.7e-61 205.3 1.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ACL93713.1 - 7.3e-50 169.1 0.5 9.1e-50 168.8 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ACL93713.1 - 1.7e-10 41.1 1.9 2.4e-10 40.6 1.9 1.2 1 0 0 1 1 1 1 KR domain Response_reg PF00072.24 ACL93714.1 - 1.9e-21 76.3 0.1 2.6e-21 75.9 0.1 1.2 1 0 0 1 1 1 1 Response regulator receiver domain HTH_8 PF02954.19 ACL93714.1 - 7.9e-07 28.8 0.7 1e-05 25.2 0.1 2.3 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family HTH_23 PF13384.6 ACL93714.1 - 2.7e-05 23.8 1.3 6.8e-05 22.5 1.3 1.7 1 0 0 1 1 1 1 Homeodomain-like domain HTH_30 PF13556.6 ACL93714.1 - 0.00017 21.3 0.3 0.00017 21.3 0.3 2.2 3 0 0 3 3 3 1 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.6 ACL93714.1 - 0.00046 20.3 0.2 0.0013 18.8 0.2 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 ACL93714.1 - 0.0021 18.0 0.3 0.0067 16.4 0.3 1.9 1 0 0 1 1 1 1 Winged helix-turn helix OKR_DC_1_N PF03709.15 ACL93714.1 - 0.0056 16.9 0.2 0.02 15.2 0.1 2.1 2 1 0 2 2 2 1 Orn/Lys/Arg decarboxylase, N-terminal domain Peripla_BP_4 PF13407.6 ACL93714.1 - 0.016 14.8 0.8 0.022 14.4 0.8 1.2 1 0 0 1 1 1 0 Periplasmic binding protein domain HTH_38 PF13936.6 ACL93714.1 - 0.018 14.8 0.6 0.035 13.9 0.6 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 ACL93714.1 - 0.066 12.6 0.1 0.17 11.3 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 MarR PF01047.22 ACL93714.1 - 0.099 12.6 0.1 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 MarR family HATPase_c PF02518.26 ACL93715.1 - 2.7e-12 47.2 0.0 4.5e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ACL93715.1 - 6.2e-09 35.8 0.3 3.3e-08 33.4 0.2 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 ACL93715.1 - 0.034 14.1 0.5 0.082 12.9 0.0 1.9 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain CPBP PF02517.16 ACL93715.1 - 7.1 7.1 7.3 0.28 11.6 0.7 2.0 2 0 0 2 2 2 0 CPBP intramembrane metalloprotease SCO1-SenC PF02630.14 ACL93716.1 - 1e-48 164.6 0.0 1.2e-48 164.4 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 ACL93716.1 - 3.4e-06 27.0 0.0 5.2e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 ACL93716.1 - 4.7e-05 23.6 0.0 6.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like PHB_depo_C PF06850.11 ACL93717.2 - 1.3e-101 338.2 0.0 1.7e-101 337.8 0.0 1.2 1 0 0 1 1 1 1 PHB de-polymerase C-terminus DUF45 PF01863.17 ACL93718.1 - 1.3e-48 165.8 0.0 1.6e-48 165.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF45 WLM PF08325.10 ACL93718.1 - 0.064 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 WLM domain Reprolysin_5 PF13688.6 ACL93718.1 - 0.27 11.3 0.0 0.39 10.8 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12 Transgly PF00912.22 ACL93719.1 - 1.4e-59 200.5 0.0 2.1e-59 200.0 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase Transpeptidase PF00905.22 ACL93719.1 - 4e-34 118.2 3.0 2.8e-33 115.4 3.0 2.0 1 1 0 1 1 1 1 Penicillin binding protein transpeptidase domain Semialdhyde_dhC PF02774.18 ACL93720.1 - 5.1e-53 179.9 0.0 6.7e-53 179.5 0.0 1.1 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 ACL93720.1 - 9.8e-32 109.9 0.0 2.2e-31 108.8 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 ACL93720.1 - 0.00019 21.0 0.4 0.0038 16.8 0.1 2.4 2 1 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain EamA PF00892.20 ACL93721.1 - 5.7e-09 36.3 29.8 7.5e-05 22.9 10.2 2.2 2 0 0 2 2 2 2 EamA-like transporter family DUF639 PF04842.12 ACL93721.1 - 0.039 13.4 0.1 0.068 12.6 0.1 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) RseC_MucC PF04246.12 ACL93721.1 - 1.6 8.7 15.1 0.34 10.9 1.6 3.8 3 1 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Beta-lactamase PF00144.24 ACL93722.1 - 3.9e-68 230.1 1.7 4.4e-68 229.9 1.7 1.0 1 0 0 1 1 1 1 Beta-lactamase Phos_pyr_kin PF08543.12 ACL93723.1 - 8.6e-11 41.7 0.0 1.3e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 ACL93723.1 - 7.9e-06 25.4 0.5 1.2e-05 24.8 0.5 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase AdoHcyase PF05221.17 ACL93724.1 - 2e-145 483.6 0.0 2.2e-145 483.4 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 ACL93724.1 - 1e-83 279.2 1.6 1.7e-83 278.6 1.6 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 ACL93724.1 - 3.9e-08 32.9 0.1 7.3e-08 32.0 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 ACL93724.1 - 2.2e-06 27.3 0.3 3.9e-06 26.5 0.3 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain THF_DHG_CYH_C PF02882.19 ACL93724.1 - 0.00022 20.6 1.9 0.00076 18.8 1.9 1.9 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TrkA_N PF02254.18 ACL93724.1 - 0.00028 21.1 0.5 0.0012 19.1 0.5 2.1 1 1 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.6 ACL93724.1 - 0.0013 19.2 0.5 0.0033 17.9 0.5 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 ACL93724.1 - 0.004 17.2 0.1 0.0084 16.2 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.21 ACL93724.1 - 0.02 14.6 0.3 0.041 13.6 0.3 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Imm27 PF15590.6 ACL93724.1 - 0.078 12.8 0.2 0.16 11.7 0.2 1.5 1 0 0 1 1 1 0 Immunity protein 27 GST_N_3 PF13417.6 ACL93727.2 - 1.6e-09 38.0 0.0 3.1e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ACL93727.2 - 6.6e-08 32.7 0.0 1.1e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ACL93727.2 - 5.5e-07 29.8 0.0 8.1e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ACL93727.2 - 0.0018 18.4 0.0 0.0026 17.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ACL93727.2 - 0.23 11.5 2.3 0.37 10.8 0.8 2.2 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GluRS_N PF18466.1 ACL93727.2 - 0.25 11.8 0.0 0.39 11.2 0.0 1.3 1 0 0 1 1 1 0 Glutamate--tRNA ligase N-terminal domain Ribonuc_red_sm PF00268.21 ACL93728.1 - 1.2e-75 254.6 0.2 1.5e-75 254.2 0.2 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain TSGA13 PF14994.6 ACL93728.1 - 0.15 11.4 0.2 0.24 10.7 0.2 1.2 1 0 0 1 1 1 0 Testis-specific gene 13 protein ApbA PF02558.16 ACL93729.1 - 5.2e-27 94.4 0.0 7.8e-27 93.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 ACL93729.1 - 3.6e-24 85.3 0.0 5.5e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal F420_oxidored PF03807.17 ACL93729.1 - 7.3e-05 23.3 0.0 0.00021 21.8 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 ACL93729.1 - 0.1 12.6 0.1 0.25 11.3 0.1 1.8 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.14 ACL93729.1 - 0.14 11.8 0.1 0.28 10.7 0.1 1.5 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain P53_tetramer PF07710.11 ACL93730.1 - 0.21 11.0 0.0 0.38 10.1 0.0 1.4 1 0 0 1 1 1 0 P53 tetramerisation motif SDF PF00375.18 ACL93731.1 - 1.3e-109 366.8 37.7 1.5e-109 366.6 37.7 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family CTV_P6 PF06706.11 ACL93731.1 - 0.68 9.7 7.2 2.3 8.0 0.7 3.7 3 0 0 3 3 3 0 Citrus tristeza virus 6-kDa protein AMNp_N PF10423.9 ACL93732.1 - 6.1e-50 168.9 0.1 1.4e-49 167.7 0.1 1.6 1 0 0 1 1 1 1 Bacterial AMP nucleoside phosphorylase N-terminus PNP_UDP_1 PF01048.20 ACL93732.1 - 3.6e-19 68.9 0.0 6.1e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily Thiolase_N PF00108.23 ACL93733.1 - 1.3e-47 162.4 0.1 1.3e-42 146.0 0.0 2.4 2 0 0 2 2 2 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 ACL93733.1 - 2.4e-42 143.5 0.4 5.7e-42 142.3 0.1 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ACL93733.1 - 1.2e-05 25.1 1.8 0.00012 21.8 1.9 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 ACL93733.1 - 0.0023 18.1 2.9 0.0076 16.4 0.0 3.2 4 1 1 5 5 5 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal NUDIX PF00293.28 ACL93734.1 - 9.9e-18 64.4 0.3 2.4e-17 63.2 0.2 1.6 2 0 0 2 2 2 1 NUDIX domain NUDIX-like PF09296.11 ACL93734.1 - 4.5e-17 62.6 0.3 1.5e-16 60.9 0.2 1.9 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 ACL93734.1 - 1.3e-14 53.6 5.2 2.4e-14 52.7 5.2 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain DZR PF12773.7 ACL93734.1 - 0.0096 15.9 0.4 0.019 15.0 0.4 1.4 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 ACL93734.1 - 0.013 15.5 0.1 0.024 14.7 0.1 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1451 PF07295.11 ACL93734.1 - 0.093 12.8 0.9 0.19 11.7 0.9 1.5 1 0 0 1 1 1 0 Zinc-ribbon containing domain Zn-ribbon_8 PF09723.10 ACL93734.1 - 0.17 12.0 0.8 0.39 10.9 0.8 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Nudix_N_2 PF14803.6 ACL93734.1 - 0.5 10.3 3.3 1.8 8.6 3.3 2.0 1 1 0 1 1 1 0 Nudix N-terminal DNA_pol3_gamma3 PF12169.8 ACL93735.2 - 8.9e-45 152.1 0.8 1.5e-44 151.4 0.8 1.4 1 0 0 1 1 1 1 DNA polymerase III subunits gamma and tau domain III DUF3646 PF12362.8 ACL93735.2 - 3.9e-35 120.6 0.0 8e-35 119.6 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III gamma and tau subunits C terminal DNA_pol3_delta2 PF13177.6 ACL93735.2 - 2.3e-33 115.3 0.0 3.2e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 ACL93735.2 - 2.6e-10 40.8 0.0 1e-09 38.9 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ACL93735.2 - 5.3e-08 33.0 0.0 2.3e-07 30.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ACL93735.2 - 4.9e-07 30.1 0.0 2e-06 28.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.12 ACL93735.2 - 6.3e-07 29.3 0.5 1.6e-05 24.7 0.0 2.5 2 1 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 ACL93735.2 - 1.3e-06 29.0 0.0 2.9e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ACL93735.2 - 1.7e-06 28.5 0.5 7.7e-06 26.4 0.4 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 ACL93735.2 - 7.4e-06 25.8 0.2 7.4e-06 25.8 0.2 3.1 2 1 0 2 2 2 1 AAA domain TsaE PF02367.17 ACL93735.2 - 1.6e-05 24.9 0.2 4.2e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 ACL93735.2 - 0.00011 22.3 0.0 0.00038 20.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 ACL93735.2 - 0.0012 18.7 0.0 0.0071 16.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 ACL93735.2 - 0.0027 16.9 0.0 0.0053 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_assoc_2 PF16193.5 ACL93735.2 - 0.0078 16.5 0.2 0.019 15.3 0.2 1.7 1 0 0 1 1 1 1 AAA C-terminal domain SRP54 PF00448.22 ACL93735.2 - 0.009 15.7 0.1 0.026 14.2 0.1 1.8 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 ACL93735.2 - 0.01 15.8 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_19 PF13245.6 ACL93735.2 - 0.01 16.2 0.5 0.055 13.8 0.5 2.2 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 ACL93735.2 - 0.024 13.9 0.1 1.8 7.7 0.0 2.1 2 0 0 2 2 2 0 TIP49 P-loop domain ResIII PF04851.15 ACL93735.2 - 0.045 13.8 0.1 5.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 ACL93735.2 - 0.051 12.6 0.2 0.16 11.0 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_28 PF13521.6 ACL93735.2 - 0.054 13.7 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ACL93735.2 - 0.09 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ACL93735.2 - 0.096 12.2 0.0 0.65 9.5 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 ACL93735.2 - 0.12 11.7 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 ACL93735.2 - 0.27 11.1 0.0 0.41 10.5 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain YbaB_DNA_bd PF02575.16 ACL93736.1 - 4.4e-27 94.2 8.0 5.2e-27 93.9 8.0 1.0 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family Toprim_4 PF13662.6 ACL93737.1 - 2.2e-21 76.1 0.0 4.4e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Toprim domain RecR PF02132.15 ACL93737.1 - 2.9e-11 42.7 0.3 5.4e-11 41.9 0.3 1.5 1 0 0 1 1 1 1 RecR protein RmuC PF02646.16 ACL93739.1 - 1.4e-90 303.4 2.0 1.9e-90 302.9 0.0 1.8 2 0 0 2 2 2 1 RmuC family RNA_lig_T4_1 PF09511.10 ACL93739.1 - 0.19 11.5 1.1 0.34 10.7 1.1 1.4 1 0 0 1 1 1 0 RNA ligase Pep_deformylase PF01327.21 ACL93740.1 - 1.5e-49 167.7 0.0 1.7e-49 167.5 0.0 1.0 1 0 0 1 1 1 1 Polypeptide deformylase DUF772 PF05598.11 ACL93742.1 - 4e-18 65.2 0.4 8.8e-18 64.1 0.0 1.8 2 0 0 2 2 2 1 Transposase domain (DUF772) DDE_Tnp_1_6 PF13751.6 ACL93742.1 - 4.1e-14 52.9 1.5 9e-14 51.8 0.0 2.1 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 ACL93742.1 - 5.8e-13 49.0 0.0 3.2e-12 46.6 0.0 2.1 1 1 0 1 1 1 1 Transposase DDE domain Fmp27_WPPW PF10359.9 ACL93742.1 - 0.012 14.5 0.5 0.016 14.1 0.5 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF501 PF04417.12 ACL93742.1 - 0.089 12.6 0.3 1 9.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF501) UPF0193 PF05250.11 ACL93742.1 - 0.18 11.6 1.8 0.31 10.8 1.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0193) CLZ PF16526.5 ACL93742.1 - 0.28 11.6 4.9 0.53 10.7 1.8 2.5 1 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MerR-DNA-bind PF09278.11 ACL93742.1 - 2.1 8.9 5.6 3.3 8.3 3.9 2.2 1 1 1 2 2 2 0 MerR, DNA binding Cupin_2 PF07883.11 ACL93743.1 - 3.1e-17 62.0 0.3 1.1e-16 60.2 0.1 1.9 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 ACL93743.1 - 5.8e-07 29.1 0.4 2e-06 27.4 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 ACL93743.1 - 0.084 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Peptidase_M20 PF01546.28 ACL93744.1 - 7.5e-38 130.3 1.4 1.4e-37 129.4 1.1 1.6 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ACL93744.1 - 1.2e-22 79.9 0.2 4e-22 78.2 0.1 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Glutaminase PF04960.15 ACL93745.1 - 8.5e-98 327.1 0.0 9.6e-98 326.9 0.0 1.0 1 0 0 1 1 1 1 Glutaminase Flavodoxin_2 PF02525.17 ACL93746.1 - 3.4e-28 98.7 0.0 4e-28 98.5 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 ACL93746.1 - 1.3e-10 41.2 0.0 1.5e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase PseudoU_synth_1 PF01416.20 ACL93747.1 - 1.2e-41 141.5 0.2 1.4e-30 105.9 0.0 2.1 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF2344 PF10105.9 ACL93747.1 - 0.03 14.2 0.0 0.043 13.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) CBM39 PF15886.5 ACL93747.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 32) Formyl_trans_N PF00551.19 ACL93748.1 - 9.8e-40 136.2 0.0 1.3e-39 135.8 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 ACL93748.1 - 3.5e-21 75.3 0.0 1.1e-20 73.7 0.0 1.8 2 0 0 2 2 2 1 Formyl transferase, C-terminal domain Apolipoprotein PF01442.18 ACL93749.1 - 0.0023 17.8 6.9 0.0027 17.6 6.9 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 ACL93749.1 - 0.0023 18.0 4.7 0.033 14.3 4.8 1.9 1 1 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) DUF4995 PF16386.5 ACL93749.1 - 0.0045 17.0 2.1 0.035 14.1 0.7 2.1 1 1 1 2 2 2 1 Domain of unknown function YtxH PF12732.7 ACL93749.1 - 0.036 14.6 16.0 0.05 14.1 5.7 2.4 1 1 1 2 2 2 0 YtxH-like protein DUF883 PF05957.13 ACL93749.1 - 0.24 12.0 10.8 1.7 9.3 2.7 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) ApoC-I PF04691.12 ACL93749.1 - 0.61 10.0 5.9 1.8 8.5 0.4 2.8 2 1 1 3 3 3 0 Apolipoprotein C-I (ApoC-1) THDPS_N_2 PF14805.6 ACL93750.1 - 1.1e-23 83.2 1.1 1.7e-23 82.6 1.1 1.3 1 0 0 1 1 1 1 Tetrahydrodipicolinate N-succinyltransferase N-terminal Hexapep_2 PF14602.6 ACL93750.1 - 1.5e-13 50.2 9.8 5.9e-13 48.3 1.1 3.4 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 ACL93750.1 - 5.3e-12 45.0 14.4 1.4e-06 27.8 0.7 3.8 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) HAD_2 PF13419.6 ACL93751.1 - 1.3e-06 28.6 0.0 2.6e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ACL93751.1 - 2.2e-05 24.9 0.0 0.21 11.9 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 ACL93751.1 - 0.0079 16.1 0.0 1.9 8.3 0.0 2.2 2 0 0 2 2 2 2 Acid Phosphatase Hydrolase_like PF13242.6 ACL93751.1 - 0.056 13.5 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like AA_kinase PF00696.28 ACL93752.1 - 3.9e-45 154.3 5.0 4.6e-45 154.1 5.0 1.0 1 0 0 1 1 1 1 Amino acid kinase family Response_reg PF00072.24 ACL93753.1 - 1.7e-10 41.1 0.0 2.2e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain HisKA_2 PF07568.12 ACL93754.1 - 3.9e-24 84.5 0.1 7.4e-24 83.6 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase PAS_9 PF13426.7 ACL93754.1 - 2.2e-23 82.5 0.0 8e-23 80.7 0.0 1.9 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 ACL93754.1 - 4e-10 39.7 0.0 1.9e-09 37.5 0.0 2.0 1 1 1 2 2 2 1 PAS fold PAS_3 PF08447.12 ACL93754.1 - 5.2e-10 39.5 0.0 1.2e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 PAS fold HATPase_c_2 PF13581.6 ACL93754.1 - 1.4e-09 37.9 0.0 4.6e-09 36.3 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PAS_4 PF08448.10 ACL93754.1 - 7.5e-08 32.6 0.0 1.6e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 PAS fold HATPase_c PF02518.26 ACL93754.1 - 1.3e-07 32.1 0.1 2.1e-06 28.2 0.0 2.6 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HWE_HK PF07536.14 ACL93754.1 - 4.6e-06 27.3 0.1 1.2e-05 25.9 0.1 1.8 1 0 0 1 1 1 1 HWE histidine kinase PAS_8 PF13188.7 ACL93754.1 - 4.3e-05 23.4 0.0 0.00013 21.9 0.0 1.8 1 0 0 1 1 1 1 PAS domain SBP_bac_11 PF13531.6 ACL93755.1 - 3.7e-41 141.4 0.6 4.7e-41 141.0 0.6 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 ACL93755.1 - 1.1e-12 48.6 2.1 1.6e-12 48.0 2.1 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein PBP_like PF12727.7 ACL93755.1 - 0.00034 19.8 0.0 0.00063 18.9 0.0 1.3 1 0 0 1 1 1 1 PBP superfamily domain UCR_Fe-S_N PF10399.9 ACL93755.1 - 0.0068 15.7 1.5 0.016 14.6 1.5 1.6 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal CytB6-F_Fe-S PF08802.10 ACL93755.1 - 0.22 11.6 2.5 0.55 10.3 2.5 1.7 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit HATPase_c PF02518.26 ACL93758.1 - 4.7e-21 75.4 0.0 6.8e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ACL93758.1 - 1.1e-16 60.6 0.5 2.3e-16 59.6 0.5 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 ACL93758.1 - 0.00011 22.1 0.1 0.00035 20.5 0.1 1.9 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 ACL93758.1 - 0.011 15.9 2.3 0.016 15.5 0.4 2.2 2 1 0 2 2 2 0 PAS fold HATPase_c_2 PF13581.6 ACL93758.1 - 0.033 14.1 0.0 0.18 11.8 0.0 2.1 1 1 1 2 2 2 0 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 ACL93758.1 - 0.06 13.3 0.0 2.5 8.1 0.0 2.2 2 0 0 2 2 2 0 GHKL domain DUF3708 PF12501.8 ACL93759.1 - 2.1e-32 112.2 7.3 2.1e-32 112.2 7.3 2.2 2 0 0 2 2 2 1 Phosphate ATP-binding cassette transporter BPD_transp_1 PF00528.22 ACL93759.1 - 9.3e-18 64.6 13.6 9.3e-18 64.6 13.6 3.3 1 1 1 3 3 3 1 Binding-protein-dependent transport system inner membrane component DUF3333 PF11812.8 ACL93760.1 - 2.8e-42 144.5 0.4 2.8e-42 144.5 0.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3333) BPD_transp_1 PF00528.22 ACL93760.1 - 1.6e-26 93.2 18.9 2.7e-26 92.4 14.2 2.8 2 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 ACL93761.2 - 8.9e-30 104.0 0.0 1.2e-29 103.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ACL93761.2 - 9e-10 38.8 0.1 0.001 18.9 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ACL93761.2 - 1.2e-07 31.4 0.0 7.5e-07 28.8 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 ACL93761.2 - 0.00021 21.1 0.0 0.00036 20.4 0.0 1.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 ACL93761.2 - 0.00041 20.9 0.0 0.00065 20.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ACL93761.2 - 0.0023 17.6 0.0 0.0049 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ACL93761.2 - 0.0024 17.8 0.0 0.0046 16.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 ACL93761.2 - 0.0042 17.4 0.0 0.012 15.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 ACL93761.2 - 0.01 15.4 0.0 0.074 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 ACL93761.2 - 0.019 15.4 0.0 0.032 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 ACL93761.2 - 0.034 14.3 0.0 0.088 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 ACL93761.2 - 0.063 13.7 0.1 1.8 9.0 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 ACL93761.2 - 0.076 12.9 0.0 0.16 11.8 0.0 1.5 2 0 0 2 2 2 0 Rad17 P-loop domain NACHT PF05729.12 ACL93761.2 - 0.15 12.0 0.0 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 NACHT domain PhoU PF01895.19 ACL93762.1 - 5.1e-42 142.2 2.2 3.6e-20 72.2 0.1 2.1 2 0 0 2 2 2 2 PhoU domain CinA_KH PF18146.1 ACL93762.1 - 0.08 13.1 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 Damage-inducible protein CinA KH domain Response_reg PF00072.24 ACL93763.1 - 2.5e-30 104.9 0.0 3.5e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 ACL93763.1 - 1.3e-28 98.8 0.1 3.7e-28 97.4 0.0 1.8 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal LytTR PF04397.15 ACL93764.1 - 1.6e-21 76.4 0.0 2.1e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 LytTr DNA-binding domain DUF2306 PF10067.9 ACL93765.1 - 3.6e-10 40.2 12.6 1.1e-09 38.7 6.4 2.1 2 0 0 2 2 2 2 Predicted membrane protein (DUF2306) Ni_hydr_CYTB PF01292.20 ACL93765.1 - 0.077 12.6 11.0 0.13 11.9 7.3 2.6 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 GARS_A PF01071.19 ACL93766.1 - 1.5e-73 246.7 0.0 2e-73 246.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 ACL93766.1 - 6.7e-30 103.7 0.3 1.5e-29 102.6 0.3 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 ACL93766.1 - 5.9e-29 100.2 0.1 1.3e-28 99.1 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp PF02222.22 ACL93766.1 - 0.0001 22.0 0.0 0.00019 21.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 ACL93766.1 - 0.00067 19.0 0.0 0.016 14.5 0.0 2.2 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 ACL93766.1 - 0.0041 17.2 0.0 0.0077 16.3 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp domain RTP1_C2 PF10304.9 ACL93766.1 - 0.22 11.3 0.2 5.3 6.8 0.0 2.5 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 2 Glyoxalase PF00903.25 ACL93767.2 - 2.2e-07 31.1 0.0 2.9e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily APH PF01636.23 ACL93768.1 - 1.9e-64 217.9 0.1 2.7e-64 217.4 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 ACL93768.1 - 1.3e-06 28.0 0.0 2.1e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 ACL93768.1 - 0.00042 20.0 0.0 0.00062 19.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase AAA_28 PF13521.6 ACL93768.1 - 0.048 13.9 0.0 0.54 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF1679 PF07914.11 ACL93768.1 - 0.075 11.9 0.0 0.21 10.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Amidohydro_1 PF01979.20 ACL93769.1 - 3.5e-62 210.7 1.7 4.5e-62 210.3 1.7 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ACL93769.1 - 4.6e-17 62.6 6.4 9.4e-10 38.5 2.5 3.2 1 1 0 2 2 2 2 Amidohydrolase family LpxK PF02606.14 ACL93770.1 - 4.8e-80 269.1 0.0 6.2e-80 268.7 0.0 1.1 1 0 0 1 1 1 1 Tetraacyldisaccharide-1-P 4'-kinase Glycos_transf_N PF04413.16 ACL93771.3 - 1.9e-53 180.8 0.0 2.7e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Glyco_trans_1_2 PF13524.6 ACL93771.3 - 0.0024 18.2 0.1 0.0058 17.0 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Cation_efflux PF01545.21 ACL93772.1 - 4.8e-40 137.4 13.2 6.4e-40 137.0 13.2 1.1 1 0 0 1 1 1 1 Cation efflux family DUF374 PF04028.13 ACL93773.1 - 2.1e-26 91.2 0.3 7e-26 89.6 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF374) ABC_tran PF00005.27 ACL93774.1 - 1e-32 113.5 0.0 1.8e-32 112.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 ACL93774.1 - 6.5e-30 104.7 0.1 9.8e-30 104.1 0.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 ACL93774.1 - 4e-09 36.2 0.0 6.5e-07 29.0 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ACL93774.1 - 4.1e-05 24.0 0.4 0.00012 22.6 0.4 1.8 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 ACL93774.1 - 0.0024 17.8 0.0 0.0057 16.6 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 ACL93774.1 - 0.0097 16.3 0.0 0.18 12.2 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 ACL93774.1 - 0.017 14.0 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_24 PF13479.6 ACL93774.1 - 0.031 14.0 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 ACL93774.1 - 0.064 13.5 0.0 0.37 11.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ACL93774.1 - 0.089 12.6 0.2 0.23 11.2 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AIF_C PF14721.6 ACL93774.1 - 0.098 13.0 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF442 PF04273.13 ACL93775.1 - 3.7e-05 23.8 0.0 7.9e-05 22.7 0.0 1.5 2 0 0 2 2 2 1 Putative phosphatase (DUF442) Y_phosphatase3 PF13350.6 ACL93775.1 - 0.00036 20.6 0.0 0.0012 18.8 0.0 1.9 2 1 0 2 2 2 1 Tyrosine phosphatase family DUF4170 PF13773.6 ACL93776.1 - 2.8e-37 126.7 0.3 3.2e-37 126.5 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4170) Inositol_P PF00459.25 ACL93777.1 - 1.2e-40 139.7 0.1 1.5e-40 139.4 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family PmbA_TldD PF01523.16 ACL93778.1 - 5.9e-59 200.2 0.3 7.4e-59 199.9 0.3 1.1 1 0 0 1 1 1 1 Putative modulator of DNA gyrase MAPEG PF01124.18 ACL93779.1 - 2.8e-25 88.7 12.3 3.2e-25 88.5 12.3 1.0 1 0 0 1 1 1 1 MAPEG family SIT PF15330.6 ACL93779.1 - 6.3 7.3 4.9 4.5 7.8 0.2 2.1 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Peptidase_M14 PF00246.24 ACL93780.1 - 1.6e-20 74.1 0.0 3.3e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 Zinc carboxypeptidase UbiD PF01977.16 ACL93782.1 - 1.9e-161 537.5 0.1 2.1e-161 537.3 0.1 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase AA_kinase PF00696.28 ACL93783.1 - 1e-41 143.1 1.4 1.5e-41 142.6 1.4 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 ACL93783.1 - 3.4e-23 81.4 0.1 1.1e-22 79.8 0.1 1.9 1 0 0 1 1 1 1 PUA domain PUA_3 PF17785.1 ACL93783.1 - 0.0016 18.2 0.0 0.0038 17.0 0.0 1.7 1 0 0 1 1 1 1 PUA-like domain UPF0113 PF03657.13 ACL93783.1 - 0.0088 16.3 0.0 0.037 14.3 0.0 2.0 2 0 0 2 2 2 1 UPF0113 PUA domain GCD14_N PF14801.6 ACL93783.1 - 0.15 11.9 0.1 0.34 10.8 0.1 1.6 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term GTP1_OBG PF01018.22 ACL93784.1 - 2.3e-57 192.9 2.8 2.3e-57 192.9 2.8 1.4 2 0 0 2 2 2 1 GTP1/OBG MMR_HSR1 PF01926.23 ACL93784.1 - 1.1e-23 83.4 0.0 1.7e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ACL93784.1 - 2e-10 40.4 0.0 1.3e-09 37.8 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B cobW PF02492.19 ACL93784.1 - 0.077 12.6 0.8 0.35 10.4 0.1 2.2 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 ACL93784.1 - 0.1 12.1 0.1 1.3 8.4 0.1 2.2 1 1 0 1 1 1 0 ADP-ribosylation factor family Acetyltransf_3 PF13302.7 ACL93786.1 - 1.7e-30 106.5 0.0 2e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ACL93786.1 - 7.6e-09 35.8 0.0 9.8e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family rve PF00665.26 ACL93786.1 - 0.076 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain Ribosomal_L27 PF01016.19 ACL93787.1 - 4.6e-37 125.9 3.3 5.1e-37 125.7 3.3 1.0 1 0 0 1 1 1 1 Ribosomal L27 protein Ribosomal_L21p PF00829.21 ACL93788.1 - 1.7e-34 118.1 0.7 3e-34 117.3 0.7 1.4 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein UvrA_inter PF17760.1 ACL93788.1 - 0.0084 16.2 0.1 0.016 15.2 0.1 1.5 1 1 0 1 1 1 1 UvrA interaction domain YtpI PF14007.6 ACL93789.1 - 0.019 15.1 2.1 0.019 15.1 2.1 2.8 2 2 1 3 3 3 0 YtpI-like protein Trp_oprn_chp PF09534.10 ACL93789.1 - 0.67 9.7 18.9 0.037 13.8 11.9 2.3 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF373 PF04123.13 ACL93789.1 - 3.3 7.1 7.0 5.9 6.2 7.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF373) cobW PF02492.19 ACL93790.1 - 1.3e-58 197.5 0.2 1.7e-58 197.1 0.2 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 ACL93790.1 - 1.1e-22 79.7 0.0 1.8e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 ACL93790.1 - 1.3e-05 25.1 0.1 0.061 13.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MeaB PF03308.16 ACL93790.1 - 0.001 18.1 2.2 0.029 13.3 0.1 2.7 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 ACL93790.1 - 0.0048 17.3 0.2 0.017 15.5 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 ACL93790.1 - 0.015 15.4 0.2 0.057 13.5 0.2 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase TsaE PF02367.17 ACL93790.1 - 0.027 14.5 0.1 0.057 13.4 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 ACL93790.1 - 0.048 14.2 0.0 0.12 12.9 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 ACL93790.1 - 0.055 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 ACL93790.1 - 0.061 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 ACL93790.1 - 0.08 12.7 0.1 0.23 11.2 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 ACL93790.1 - 0.083 13.0 0.2 0.15 12.2 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ACL93790.1 - 0.12 12.8 0.8 0.27 11.7 0.8 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ACL93790.1 - 0.17 12.4 0.1 0.17 12.4 0.1 2.1 2 1 0 2 2 2 0 AAA domain Zip PF02535.22 ACL93790.1 - 1.5 8.0 8.3 2.1 7.5 8.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.14 ACL93790.1 - 4.2 6.7 18.4 7.8 5.8 18.4 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region ExbD PF02472.16 ACL93791.1 - 9.9e-24 84.0 0.1 1.4e-23 83.5 0.1 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR WD40 PF00400.32 ACL93793.1 - 5.6e-11 42.8 0.3 0.74 10.8 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ACL93793.1 - 7.6e-09 35.8 0.0 0.73 10.2 0.0 5.3 2 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 ACL93793.1 - 0.011 15.7 0.0 5.6 7.0 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Nitroreductase PF00881.24 ACL93794.1 - 2.5e-30 105.8 0.0 4.2e-30 105.0 0.0 1.4 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 ACL93794.1 - 1.8e-09 37.5 0.0 0.0082 15.7 0.0 3.1 2 1 1 3 3 3 3 Putative TM nitroreductase Transgly PF00912.22 ACL93795.1 - 5.2e-48 162.9 0.0 6.7e-48 162.5 0.0 1.0 1 0 0 1 1 1 1 Transglycosylase Acetyltransf_3 PF13302.7 ACL93796.1 - 3.1e-29 102.4 0.1 3.8e-29 102.1 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ACL93796.1 - 0.001 19.3 0.0 0.0013 19.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Nup214_FG PF18617.1 ACL93796.1 - 0.11 13.1 0.2 0.17 12.4 0.2 1.3 1 0 0 1 1 1 0 Nucleoporin Nup214 phenylalanine-glycine (FG) domain TOBE PF03459.17 ACL93797.1 - 1.4e-30 105.3 6.6 5.2e-18 65.1 0.5 2.5 2 0 0 2 2 2 2 TOBE domain HTH_1 PF00126.27 ACL93797.1 - 3.2e-16 59.0 4.3 7.9e-16 57.8 0.4 2.9 3 0 0 3 3 3 1 Bacterial regulatory helix-turn-helix protein, lysR family TOBE_2 PF08402.10 ACL93797.1 - 0.0013 18.9 1.4 0.0044 17.1 0.1 2.3 2 1 0 2 2 2 1 TOBE domain HTH_8 PF02954.19 ACL93797.1 - 0.085 12.7 0.3 0.2 11.5 0.3 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family HlyD PF00529.20 ACL93797.1 - 0.089 12.7 0.0 0.33 10.9 0.0 2.0 1 1 0 1 1 1 0 HlyD membrane-fusion protein of T1SS SBP_bac_11 PF13531.6 ACL93798.1 - 1.7e-45 155.5 7.5 2e-45 155.3 7.5 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 ACL93798.1 - 2.1e-12 47.6 4.2 1.7e-09 38.0 4.2 2.1 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein BPD_transp_1 PF00528.22 ACL93799.1 - 1.4e-18 67.3 14.1 2e-18 66.8 14.1 1.1 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component Ndc1_Nup PF09531.10 ACL93799.1 - 0.92 8.1 4.0 1.3 7.6 4.0 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup LytTR PF04397.15 ACL93800.2 - 2.8e-16 59.5 0.0 4.3e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 LytTr DNA-binding domain CcmH PF03918.14 ACL93800.2 - 0.034 13.4 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C biogenesis protein HXXEE PF13787.6 ACL93800.2 - 0.067 14.0 0.9 0.13 13.0 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function with HXXEE motif DUF2306 PF10067.9 ACL93801.1 - 3.8e-08 33.7 9.6 3.8e-08 33.7 9.6 1.6 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) DUF420 PF04238.12 ACL93801.1 - 0.0051 17.1 4.1 0.0053 17.0 0.1 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF420) DUF2141 PF09912.9 ACL93802.1 - 1.5e-29 102.2 0.0 1.8e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2141) RPE65 PF03055.15 ACL93803.1 - 2e-83 281.2 0.0 2.2e-83 281.0 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein TAT_signal PF10518.9 ACL93803.1 - 4.2e-05 23.2 0.2 0.00014 21.6 0.2 1.9 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence TetR_C_30 PF17939.1 ACL93804.2 - 3.2e-33 114.4 0.0 5.6e-33 113.6 0.0 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ACL93804.2 - 2.5e-16 59.2 1.3 4.7e-16 58.3 1.3 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TonB_dep_Rec PF00593.24 ACL93805.2 - 2.4e-41 143.1 31.3 2.4e-41 143.1 31.3 2.1 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 ACL93805.2 - 8.1e-19 68.2 0.4 8.1e-19 68.2 0.4 2.7 3 0 0 3 3 3 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 ACL93805.2 - 5.6e-09 35.5 4.3 1.8e-08 33.8 4.3 1.7 1 1 0 1 1 1 1 Outer membrane protein beta-barrel family BAT PF15915.5 ACL93805.2 - 0.49 10.3 4.4 11 5.9 1.7 2.5 2 0 0 2 2 2 0 GAF and HTH_10 associated domain MFS_1 PF07690.16 ACL93806.1 - 1.8e-48 165.3 46.4 1.8e-48 165.3 46.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 ACL93806.1 - 2e-12 46.2 8.2 1.2e-09 37.1 0.5 2.5 1 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family ATP-grasp_2 PF08442.10 ACL93807.1 - 2.3e-74 249.4 0.0 3.5e-74 248.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 ACL93807.1 - 8.3e-27 93.9 5.2 1.8e-26 92.8 2.3 2.4 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.6 ACL93807.1 - 4.3e-11 42.7 1.2 4.5e-10 39.4 1.2 2.3 1 1 0 1 1 1 1 ATP-grasp domain CoA_binding PF02629.19 ACL93808.1 - 4.3e-32 110.7 4.0 5.1e-32 110.4 0.7 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 ACL93808.1 - 2.3e-19 69.7 1.0 3.5e-19 69.1 1.0 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 ACL93808.1 - 1.1e-07 31.7 0.1 1.7e-07 31.1 0.1 1.3 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 ACL93808.1 - 0.00076 20.0 0.0 0.0031 18.0 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain Transket_pyr PF02779.24 ACL93809.1 - 6.8e-66 221.3 0.0 1.2e-65 220.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 ACL93809.1 - 1.7e-53 181.5 0.0 3.4e-53 180.5 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 ACL93809.1 - 2.2e-50 170.3 0.0 4.5e-50 169.3 0.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 ACL93809.1 - 1e-17 63.4 2.0 2.1e-17 62.4 2.0 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus 2-oxoacid_dh PF00198.23 ACL93810.1 - 8.1e-83 277.4 0.2 1.1e-82 277.0 0.2 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 ACL93810.1 - 5.2e-20 71.1 3.4 1.4e-19 69.7 1.7 2.6 3 0 0 3 3 3 1 Biotin-requiring enzyme E3_binding PF02817.17 ACL93810.1 - 8.2e-12 45.3 1.4 2.3e-11 43.8 1.4 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 ACL93810.1 - 8.1e-06 25.6 1.9 0.36 10.7 0.1 3.5 2 1 1 3 3 3 3 Biotin-lipoyl like PYNP_C PF07831.13 ACL93810.1 - 0.067 12.9 0.0 3.2 7.5 0.0 2.7 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain HlyD_D23 PF16576.5 ACL93810.1 - 0.26 10.5 4.0 0.82 8.8 0.2 2.8 2 1 1 3 3 3 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion GCV_H PF01597.19 ACL93810.1 - 0.3 11.0 1.7 1.4 8.8 0.2 2.6 3 0 0 3 3 3 0 Glycine cleavage H-protein DUF3088 PF11287.8 ACL93811.2 - 1.7e-32 111.5 0.0 1.9e-32 111.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3088) PhnA_Zn_Ribbon PF08274.12 ACL93811.2 - 0.12 12.3 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 PhnA Zinc-Ribbon Esterase PF00756.20 ACL93812.2 - 4.7e-26 92.0 0.0 5.6e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 ACL93812.2 - 0.021 14.3 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 ACL93812.2 - 0.03 13.6 0.0 0.044 13.0 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Pyr_redox_2 PF07992.14 ACL93813.2 - 3.5e-72 243.1 6.4 3.5e-72 243.1 6.4 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ACL93813.2 - 2.7e-42 143.5 0.9 7e-41 138.9 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 ACL93813.2 - 6.6e-21 74.7 11.9 9.4e-19 67.8 0.4 3.7 3 1 1 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ACL93813.2 - 5.1e-10 39.1 1.4 1e-09 38.1 1.4 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ACL93813.2 - 9.4e-10 38.4 1.3 9.4e-10 38.4 1.3 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 ACL93813.2 - 1.2e-07 31.3 0.5 6.3e-05 22.3 0.0 2.6 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 ACL93813.2 - 2.1e-07 30.0 9.6 0.00016 20.5 1.8 4.0 3 1 1 4 4 4 2 HI0933-like protein GIDA PF01134.22 ACL93813.2 - 1.3e-06 27.7 12.2 5.1e-05 22.5 8.6 3.0 2 1 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 ACL93813.2 - 4.2e-06 26.9 4.6 0.0024 18.1 1.6 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 ACL93813.2 - 6.1e-06 25.7 13.3 0.04 13.2 0.0 3.6 3 1 1 4 4 4 3 FAD binding domain FAD_binding_2 PF00890.24 ACL93813.2 - 1.5e-05 24.3 3.3 1.5e-05 24.3 3.3 3.7 3 1 1 4 4 4 1 FAD binding domain AlaDh_PNT_C PF01262.21 ACL93813.2 - 2.8e-05 23.5 9.1 0.01 15.2 0.2 3.2 3 1 1 4 4 4 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 ACL93813.2 - 6.4e-05 22.3 3.3 0.00026 20.3 0.9 2.3 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 ACL93813.2 - 0.012 14.7 4.7 0.059 12.4 1.3 2.5 2 1 0 2 2 2 0 Lycopene cyclase protein XdhC_C PF13478.6 ACL93813.2 - 0.029 14.9 0.1 2 8.9 0.1 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain 2-Hacid_dh_C PF02826.19 ACL93813.2 - 0.037 13.4 0.4 0.95 8.8 0.0 2.7 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Amino_oxidase PF01593.24 ACL93813.2 - 0.17 11.1 1.5 2.2 7.5 0.0 2.6 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase DAO PF01266.24 ACL93813.2 - 0.37 10.3 21.2 0.66 9.5 1.3 4.3 3 1 1 4 4 4 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 ACL93813.2 - 2.1 8.2 6.7 0.18 11.7 0.3 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MCPsignal PF00015.21 ACL93815.1 - 1.1e-52 178.4 22.6 1.1e-52 178.4 22.6 3.9 3 1 0 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 ACL93815.1 - 4.8e-07 30.0 2.9 0.0003 21.1 0.1 4.8 4 1 0 4 4 3 1 HAMP domain Dynamitin PF04912.14 ACL93815.1 - 0.0059 16.0 15.5 0.0065 15.9 3.4 2.6 3 0 0 3 3 3 2 Dynamitin Sec8_exocyst PF04048.14 ACL93815.1 - 0.047 13.6 11.5 2.4 8.0 0.0 4.0 3 1 0 4 4 4 0 Sec8 exocyst complex component specific domain BLOC1_2 PF10046.9 ACL93815.1 - 0.11 12.8 16.2 7.9 6.9 0.1 5.5 3 2 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Serine_rich PF08824.10 ACL93815.1 - 0.21 11.6 8.1 0.69 9.9 0.7 3.3 1 1 2 3 3 3 0 Serine rich protein interaction domain SKA1 PF07160.12 ACL93815.1 - 0.21 11.4 0.1 0.21 11.4 0.1 3.3 4 0 0 4 4 4 0 Spindle and kinetochore-associated protein 1 Syntaxin-6_N PF09177.11 ACL93815.1 - 0.32 11.6 11.2 19 5.9 0.0 4.5 3 2 0 3 3 3 0 Syntaxin 6, N-terminal ABC_tran_Xtn PF12848.7 ACL93815.1 - 0.69 10.0 11.8 0.9 9.6 0.1 3.7 3 0 0 3 3 3 0 ABC transporter BORCS8 PF10167.9 ACL93815.1 - 1.8 8.5 5.4 2.5 8.1 0.2 3.4 3 1 0 3 3 3 0 BLOC-1-related complex sub-unit 8 V_ATPase_I PF01496.19 ACL93815.1 - 5.8 4.7 8.9 2.9 5.7 6.0 1.9 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Laminin_II PF06009.12 ACL93815.1 - 8.8 6.3 22.9 5.3 7.0 6.2 4.1 2 1 0 3 3 3 0 Laminin Domain II Phage_integrase PF00589.22 ACL93816.1 - 3.2e-38 131.2 0.0 4.8e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 ACL93816.1 - 1e-16 61.0 4.4 6.4e-16 58.4 2.6 2.5 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 ACL93816.1 - 1e-07 32.3 0.0 2.6e-07 31.0 0.0 1.6 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Integrase_1 PF12835.7 ACL93816.1 - 0.021 15.0 0.0 0.076 13.1 0.0 2.0 1 1 0 1 1 1 0 Integrase DUF484 PF04340.12 ACL93817.1 - 2.6e-77 259.5 0.1 2.9e-77 259.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF484 PriA_C PF18074.1 ACL93818.1 - 2.9e-16 60.1 0.0 9.6e-16 58.4 0.0 2.0 1 0 0 1 1 1 1 Primosomal protein N C-terminal domain DEAD PF00270.29 ACL93818.1 - 9.7e-16 58.0 0.0 1.8e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase PriA_3primeBD PF17764.1 ACL93818.1 - 1.3e-15 57.1 0.0 2.1e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 3′ DNA-binding domain (3′BD) ResIII PF04851.15 ACL93818.1 - 3.4e-09 36.9 0.0 7e-09 35.9 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ACL93818.1 - 4.4e-09 36.7 0.0 4.1e-07 30.3 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-HYPF PF07503.12 ACL93818.1 - 0.031 14.1 0.2 4.2 7.2 0.0 2.3 2 0 0 2 2 2 0 HypF finger PriA_CRR PF18319.1 ACL93818.1 - 0.035 14.1 0.0 0.035 14.1 0.0 2.5 3 0 0 3 3 3 0 PriA DNA helicase Cys-rich region (CRR) domain zf-UDP PF14569.6 ACL93818.1 - 0.041 14.0 0.1 0.066 13.3 0.1 1.3 1 0 0 1 1 1 0 Zinc-binding RING-finger Imm49 PF15575.6 ACL93818.1 - 0.043 13.6 0.1 0.12 12.1 0.1 1.7 1 0 0 1 1 1 0 Immunity protein 49 DZR PF12773.7 ACL93818.1 - 0.06 13.4 0.6 0.11 12.5 0.6 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-IS66 PF13005.7 ACL93818.1 - 0.29 11.6 1.7 1.1 9.7 0.2 2.5 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 Zn-ribbon_8 PF09723.10 ACL93818.1 - 0.33 11.1 1.2 4.3 7.5 0.2 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 ACL93818.1 - 0.54 9.7 1.8 3.2 7.3 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain TerC PF03741.16 ACL93819.1 - 2.2e-50 170.8 12.7 2.8e-50 170.5 12.7 1.1 1 0 0 1 1 1 1 Integral membrane protein TerC family Mtd_N PF18454.1 ACL93819.1 - 0.092 12.8 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Major tropism determinant N-terminal domain TssN PF17555.2 ACL93819.1 - 5.4 6.3 7.1 3.3 7.0 0.8 2.4 2 1 0 2 2 2 0 Type VI secretion system, TssN Acyl_transf_3 PF01757.22 ACL93820.1 - 6.4e-21 74.8 37.7 8.9e-21 74.3 37.7 1.1 1 0 0 1 1 1 1 Acyltransferase family CHAP PF05257.16 ACL93821.1 - 4.6e-11 43.1 0.3 1e-10 42.0 0.3 1.6 1 0 0 1 1 1 1 CHAP domain Pentapeptide PF00805.22 ACL93822.1 - 5.4e-71 233.6 45.8 1.2e-13 50.4 0.7 8.8 4 3 3 8 8 8 8 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 ACL93822.1 - 2.2e-29 101.4 0.0 6.1e-05 23.1 0.2 6.7 4 2 2 6 6 6 6 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.6 ACL93822.1 - 1.1e-24 86.3 0.0 2.5e-05 24.4 0.0 6.0 3 3 2 5 5 5 5 Pentapeptide repeats (9 copies) RelB_leu_zip PF16180.5 ACL93822.1 - 0.42 10.6 3.9 12 6.0 0.0 3.9 4 2 0 4 4 4 0 RelB leucine zipper MipA PF06629.12 ACL93823.1 - 3.9e-50 171.1 3.2 4.5e-50 170.9 3.2 1.0 1 0 0 1 1 1 1 MltA-interacting protein MipA Abhydrolase_4 PF08386.10 ACL93824.1 - 3.3e-19 68.9 0.0 6.8e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 ACL93824.1 - 3.3e-14 53.2 0.0 1.7e-13 50.8 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold ECH_1 PF00378.20 ACL93825.1 - 3.2e-41 141.3 0.0 6.9e-41 140.2 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ACL93825.1 - 2e-22 80.2 0.0 1.3e-20 74.2 0.0 1.9 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase SH3_3 PF08239.11 ACL93826.2 - 8.4e-10 38.8 0.1 1.4e-09 38.1 0.1 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain Rick_17kDa_Anti PF05433.15 ACL93826.2 - 3.8e-09 36.3 21.2 3.8e-09 36.3 21.2 3.0 4 0 0 4 4 4 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 ACL93826.2 - 5.9e-09 35.8 13.3 5.9e-09 35.8 13.3 3.3 3 1 0 3 3 3 1 Glycine zipper Gly-zipper_YMGG PF13441.6 ACL93826.2 - 1.9e-08 33.9 14.4 1.9e-08 33.9 14.4 2.9 3 1 0 3 3 3 1 YMGG-like Gly-zipper 17kDa_Anti_2 PF16998.5 ACL93826.2 - 0.00057 19.8 1.5 0.38 10.7 0.1 2.4 2 0 0 2 2 2 2 17 kDa outer membrane surface antigen SH3_4 PF06347.13 ACL93826.2 - 0.0011 18.7 0.1 0.0023 17.7 0.1 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain DUF4453 PF14627.6 ACL93826.2 - 0.0016 18.5 0.1 0.004 17.2 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4453) ATPase_gene1 PF09527.10 ACL93826.2 - 0.095 12.9 0.9 0.095 12.9 0.9 2.2 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter DUF1729 PF08354.10 ACL93826.2 - 0.16 10.8 0.1 0.24 10.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) Romo1 PF10247.9 ACL93826.2 - 2.2 8.7 10.1 0.45 10.9 0.4 3.1 2 1 1 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 Abhydrolase_6 PF12697.7 ACL93827.1 - 4.8e-24 86.2 10.5 5.9e-24 85.9 10.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ACL93827.1 - 4.8e-17 62.0 0.0 4e-16 59.0 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ACL93827.1 - 1.4e-13 51.1 0.0 2.4e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 ACL93827.1 - 1.1e-06 28.5 0.0 1.4e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 ACL93827.1 - 8.4e-05 22.8 0.0 0.00015 22.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.25 ACL93827.1 - 0.036 13.9 0.0 0.053 13.4 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.7 ACL93827.1 - 0.041 13.6 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 ACL93827.1 - 0.073 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF2048 PF09752.9 ACL93827.1 - 0.15 11.1 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Ndr PF03096.14 ACL93827.1 - 0.24 10.1 0.0 0.32 9.7 0.0 1.1 1 0 0 1 1 1 0 Ndr family 4HBT_2 PF13279.6 ACL93828.1 - 1.5e-17 64.2 0.0 1.2e-09 38.7 0.0 2.2 2 0 0 2 2 2 2 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 ACL93828.1 - 0.0022 17.3 0.0 0.0045 16.3 0.0 1.5 2 0 0 2 2 2 1 Acyl-ACP thioesterase 4HBT PF03061.22 ACL93828.1 - 0.0085 16.4 0.1 0.14 12.5 0.0 2.3 2 0 0 2 2 2 1 Thioesterase superfamily FUR PF01475.19 ACL93829.2 - 8.7e-09 35.6 0.0 1.3e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Ferric uptake regulator family HTH_11 PF08279.12 ACL93829.2 - 0.018 15.0 0.0 0.78 9.7 0.0 2.8 2 1 0 2 2 2 0 HTH domain PadR PF03551.14 ACL93829.2 - 0.04 13.9 0.0 0.083 12.9 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family PAP2 PF01569.21 ACL93830.1 - 1e-09 38.2 0.0 1.7e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 PAP2 superfamily Apelin PF15360.6 ACL93830.1 - 0.044 14.3 0.0 0.093 13.3 0.0 1.4 1 0 0 1 1 1 0 APJ endogenous ligand DUF2849 PF11011.8 ACL93830.1 - 0.43 11.3 2.7 15 6.3 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2849) DS PF01916.17 ACL93831.1 - 9e-86 287.7 0.4 1e-85 287.5 0.4 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Herpes_UL49_2 PF04823.12 ACL93831.1 - 0.083 13.0 0.4 0.22 11.7 0.4 1.7 1 0 0 1 1 1 0 Herpesvirus UL49 tegument protein Orn_Arg_deC_N PF02784.16 ACL93832.1 - 2.5e-41 141.7 0.0 3.3e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 ACL93832.1 - 7.1e-06 26.2 0.0 1.1e-05 25.5 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 ACL93832.1 - 0.0046 16.6 0.4 0.0064 16.2 0.4 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain ABC_tran PF00005.27 ACL93833.1 - 1.7e-29 103.1 0.0 2.3e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ACL93833.1 - 5.7e-10 39.5 0.1 2.8e-05 24.1 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ACL93833.1 - 2.3e-05 24.1 0.1 4.5e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 ACL93833.1 - 5.1e-05 22.8 0.0 0.25 10.7 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ACL93833.1 - 5.7e-05 23.6 0.4 0.00014 22.3 0.4 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ACL93833.1 - 0.0001 22.6 0.3 0.0077 16.5 0.1 2.2 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ACL93833.1 - 0.0004 20.3 0.3 0.0015 18.5 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 ACL93833.1 - 0.0041 17.7 0.1 0.12 12.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 ACL93833.1 - 0.0056 16.4 0.0 0.065 12.9 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 ACL93833.1 - 0.0095 15.7 0.1 0.069 12.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ACL93833.1 - 0.012 15.8 0.1 0.059 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 ACL93833.1 - 0.015 15.1 0.4 0.084 12.6 0.1 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 ACL93833.1 - 0.022 14.5 0.1 0.17 11.6 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein Rad17 PF03215.15 ACL93833.1 - 0.024 14.6 0.0 0.084 12.8 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_23 PF13476.6 ACL93833.1 - 0.026 15.0 0.0 0.042 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ACL93833.1 - 0.028 14.3 0.1 0.074 13.0 0.0 1.6 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 ACL93833.1 - 0.031 14.3 0.1 0.17 12.0 0.0 2.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_25 PF13481.6 ACL93833.1 - 0.039 13.5 0.1 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 ACL93833.1 - 0.039 13.3 0.1 0.24 10.7 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 ACL93833.1 - 0.064 12.3 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Dynamin_N PF00350.23 ACL93833.1 - 0.078 13.0 0.1 0.17 11.9 0.1 1.6 2 0 0 2 2 2 0 Dynamin family AAA_28 PF13521.6 ACL93833.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 ACL93833.1 - 0.15 12.4 0.2 2.3 8.5 0.2 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 ACL93833.1 - 0.15 11.2 0.1 0.29 10.3 0.1 1.5 2 0 0 2 2 2 0 NB-ARC domain Adeno_IVa2 PF02456.15 ACL93833.1 - 0.2 10.4 0.1 0.48 9.2 0.0 1.5 2 0 0 2 2 2 0 Adenovirus IVa2 protein G-alpha PF00503.20 ACL93833.1 - 0.27 10.3 0.0 0.43 9.7 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Phosphonate-bd PF12974.7 ACL93834.1 - 8.8e-60 202.3 0.0 1.1e-59 202.0 0.0 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein BPD_transp_1 PF00528.22 ACL93835.1 - 7.3e-19 68.2 8.2 7.3e-19 68.2 8.2 1.9 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component 2-Hacid_dh_C PF02826.19 ACL93835.1 - 0.17 11.2 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF21 PF01595.20 ACL93836.1 - 5.9e-42 143.3 6.1 8.7e-42 142.8 6.1 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 ACL93836.1 - 1.8e-22 79.1 0.2 3.7e-22 78.1 0.2 1.5 1 0 0 1 1 1 1 Transporter associated domain CBS PF00571.28 ACL93836.1 - 4.5e-10 39.8 0.1 3e-05 24.4 0.0 2.6 2 0 0 2 2 2 2 CBS domain ATP-synt_B PF00430.18 ACL93837.1 - 1e-20 74.2 25.1 1.3e-20 73.8 25.1 1.1 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) Mt_ATP-synt_B PF05405.14 ACL93837.1 - 3.6e-05 23.4 2.1 4.7e-05 23.1 1.7 1.4 1 1 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Spore_III_AF PF09581.10 ACL93837.1 - 0.0078 16.3 2.1 0.012 15.7 2.1 1.3 1 0 0 1 1 1 1 Stage III sporulation protein AF (Spore_III_AF) PA26 PF04636.13 ACL93837.1 - 0.028 13.4 0.5 0.034 13.1 0.5 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) LMBR1 PF04791.16 ACL93837.1 - 0.077 11.9 0.0 0.087 11.7 0.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein XRN_M PF17846.1 ACL93837.1 - 0.11 11.5 0.5 0.12 11.3 0.5 1.0 1 0 0 1 1 1 0 Xrn1 helical domain ARGLU PF15346.6 ACL93837.1 - 0.3 10.9 17.9 0.38 10.6 17.9 1.1 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 DUF3584 PF12128.8 ACL93837.1 - 2.7 5.4 17.8 3.3 5.1 17.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TMPIT PF07851.13 ACL93837.1 - 2.7 7.1 4.3 3.5 6.8 4.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein YlqD PF11068.8 ACL93837.1 - 4.7 7.6 14.6 2.8 8.3 3.7 2.0 1 1 1 2 2 2 0 YlqD protein Macoilin PF09726.9 ACL93837.1 - 7.7 4.9 15.2 9.5 4.6 15.2 1.0 1 0 0 1 1 1 0 Macoilin family ATP-synt_B PF00430.18 ACL93838.1 - 8.3e-20 71.2 24.8 1e-19 71.0 24.8 1.1 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) YMF19 PF02326.15 ACL93838.1 - 4.2e-06 27.4 0.0 1e-05 26.2 0.0 1.6 1 1 1 2 2 2 1 Plant ATP synthase F0 tRNA_anti-like PF12869.7 ACL93838.1 - 0.018 14.7 3.5 0.024 14.2 3.5 1.3 1 0 0 1 1 1 0 tRNA_anti-like Glycophorin_A PF01102.18 ACL93838.1 - 0.078 13.2 2.6 0.64 10.3 0.0 2.4 2 1 0 2 2 2 0 Glycophorin A ResB PF05140.14 ACL93838.1 - 0.099 11.4 2.3 0.13 11.0 2.3 1.1 1 0 0 1 1 1 0 ResB-like family Presenilin PF01080.17 ACL93838.1 - 0.23 10.2 0.8 0.29 9.9 0.8 1.1 1 0 0 1 1 1 0 Presenilin Spore_III_AF PF09581.10 ACL93838.1 - 1.9 8.5 8.3 3 7.8 8.3 1.4 1 1 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) TUTF7_u4 PF16631.5 ACL93838.1 - 2.3 8.9 8.2 6.3 7.5 7.0 2.0 1 1 0 1 1 1 0 Unstructured region 4 on terminal uridylyltransferase 7 ATP-synt_C PF00137.21 ACL93839.1 - 1.2e-11 44.7 11.6 1.5e-11 44.5 11.6 1.1 1 0 0 1 1 1 1 ATP synthase subunit C ATPase_gene1 PF09527.10 ACL93839.1 - 0.43 10.8 11.9 0.077 13.2 4.3 2.1 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter ATP-synt_A PF00119.20 ACL93840.1 - 1.6e-54 185.0 26.5 2e-54 184.8 26.5 1.0 1 0 0 1 1 1 1 ATP synthase A chain DUF1515 PF07439.11 ACL93840.1 - 6 6.9 6.5 4.3 7.4 3.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) ATPase_gene1 PF09527.10 ACL93841.1 - 1.1e-10 41.5 7.1 1.4e-10 41.2 7.1 1.1 1 0 0 1 1 1 1 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter DUF1761 PF08570.10 ACL93841.1 - 0.011 15.9 0.1 0.015 15.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1761) CbtA PF09490.10 ACL93841.1 - 0.044 13.5 0.5 0.096 12.4 0.6 1.6 1 1 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) DUF2776 PF10951.8 ACL93841.1 - 0.22 10.7 0.0 0.26 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2776) YitT_membrane PF02588.15 ACL93841.1 - 0.72 9.2 4.7 0.39 10.0 0.7 1.9 1 1 1 2 2 2 0 Uncharacterised 5xTM membrane BCR, YitT family COG1284 Vfa1 PF08432.10 ACL93842.1 - 0.28 11.5 13.3 0.44 10.9 13.3 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 ST7 PF04184.12 ACL93842.1 - 3.2 6.1 7.7 3.4 6.0 7.7 1.1 1 0 0 1 1 1 0 ST7 protein CDC27 PF09507.10 ACL93842.1 - 4.7 6.5 18.4 5.6 6.2 18.4 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TauE PF01925.19 ACL93843.2 - 4.1e-42 144.4 39.0 4.7e-42 144.2 39.0 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE SMC_N PF02463.19 ACL93844.1 - 1.3e-57 194.8 0.0 1.6e-57 194.5 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ACL93844.1 - 1.5e-17 64.8 0.0 1.5e-17 64.8 0.0 2.9 3 2 0 3 3 3 1 AAA domain AAA_21 PF13304.6 ACL93844.1 - 1.6e-12 47.9 0.0 1.7e-07 31.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 ACL93844.1 - 2.8e-06 27.3 0.0 4.1e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 ACL93844.1 - 7.7e-05 23.2 0.1 0.0043 17.6 0.0 3.5 3 1 0 3 3 3 1 ABC transporter AAA_29 PF13555.6 ACL93844.1 - 0.001 18.7 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.14 ACL93844.1 - 0.062 13.3 1.0 14 5.7 0.1 3.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) SMC_hinge PF06470.13 ACL93844.1 - 0.22 11.8 5.1 0.51 10.6 0.0 3.3 2 0 0 2 2 2 0 SMC proteins Flexible Hinge Domain Nsp1_C PF05064.13 ACL93844.1 - 0.69 9.7 3.1 4.4 7.1 0.2 3.2 3 0 0 3 3 3 0 Nsp1-like C-terminal region AAA PF00004.29 ACL93844.1 - 0.88 10.0 4.5 12 6.4 0.0 3.8 4 2 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) Thioredoxin_4 PF13462.6 ACL93845.1 - 2.3e-29 102.7 0.0 2.8e-29 102.4 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 ACL93845.1 - 0.0018 18.1 0.4 0.0048 16.7 0.1 1.7 1 1 1 2 2 2 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 ACL93846.1 - 3.8e-42 144.3 0.1 4.6e-42 144.0 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 ACL93846.1 - 7.8e-12 45.4 1.8 4.5e-09 36.4 0.2 2.1 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 ACL93846.1 - 0.061 13.8 0.0 11 6.6 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain DciA PF05258.12 ACL93847.1 - 6.2e-15 55.4 0.0 1.1e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Dna[CI] antecedent, DciA NUDIX_4 PF14815.6 ACL93848.1 - 6.8e-18 64.7 0.0 1.3e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.25 ACL93848.1 - 8e-16 58.4 0.0 1.3e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 ACL93848.1 - 1.8e-07 30.7 1.0 1.4e-06 27.8 0.1 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 ACL93848.1 - 1.9 8.9 5.3 3.6 8.1 5.3 1.5 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III N6_N4_Mtase PF01555.18 ACL93849.1 - 1.9e-59 201.2 0.0 2.4e-59 200.8 0.0 1.1 1 0 0 1 1 1 1 DNA methylase RAMA PF18755.1 ACL93849.1 - 2.1e-19 69.9 0.0 5.6e-19 68.6 0.0 1.7 2 0 0 2 2 2 1 Restriction Enzyme Adenine Methylase Associated UPF0020 PF01170.18 ACL93849.1 - 0.00023 20.9 0.0 0.43 10.2 0.0 2.9 3 0 0 3 3 3 2 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 ACL93849.1 - 0.011 16.4 0.0 1.2 9.9 0.0 3.1 2 1 1 3 3 3 0 Methyltransferase domain Cons_hypoth95 PF03602.15 ACL93849.1 - 0.015 14.9 0.0 0.14 11.7 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 ACL93849.1 - 0.04 13.7 0.0 4 7.2 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_15 PF09445.10 ACL93849.1 - 0.069 12.7 0.0 4.8 6.7 0.0 2.3 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.12 ACL93849.1 - 0.098 13.3 0.0 84 3.9 0.0 3.2 3 0 0 3 3 3 0 Methyltransferase domain MethyltransfD12 PF02086.15 ACL93849.1 - 0.12 12.0 0.2 2.5 7.7 0.0 2.5 3 0 0 3 3 3 0 D12 class N6 adenine-specific DNA methyltransferase RNase_HII PF01351.18 ACL93850.1 - 3.5e-35 121.7 0.0 4e-35 121.5 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease HII Biotin_carb_N PF00289.22 ACL93850.1 - 0.053 14.1 0.0 0.091 13.3 0.0 1.4 1 0 0 1 1 1 0 Biotin carboxylase, N-terminal domain Glyco_hydro_16 PF00722.21 ACL93851.1 - 2e-25 89.3 0.0 5.7e-25 87.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 ACL93851.1 - 1.2e-10 40.5 0.3 0.00052 18.5 0.0 2.7 2 1 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) MFS_1 PF07690.16 ACL93852.1 - 2.5e-23 82.6 40.6 2.5e-23 82.6 40.6 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Adenine_glyco PF03352.13 ACL93853.1 - 1.1e-72 243.5 0.0 1.3e-72 243.3 0.0 1.0 1 0 0 1 1 1 1 Methyladenine glycosylase Abhydrolase_6 PF12697.7 ACL93855.1 - 6.8e-16 59.5 3.7 9.9e-16 59.0 3.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ACL93855.1 - 2.5e-15 56.8 0.1 1.2e-14 54.6 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 ACL93855.1 - 0.00014 21.6 0.2 0.00019 21.2 0.2 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 ACL93855.1 - 0.00049 19.4 0.2 0.00062 19.1 0.2 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 ACL93855.1 - 0.0039 17.3 0.2 0.017 15.2 0.2 1.9 2 0 0 2 2 2 1 Thioesterase domain PGAP1 PF07819.13 ACL93855.1 - 0.037 13.7 0.1 0.57 9.9 0.0 2.2 2 0 0 2 2 2 0 PGAP1-like protein DUF676 PF05057.14 ACL93855.1 - 0.18 11.3 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) FAD-SLDH PF12318.8 ACL93855.1 - 0.28 11.3 3.3 15 5.6 0.4 2.5 2 1 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase GCV_T PF01571.21 ACL93856.2 - 4.1e-10 39.5 0.0 6.3e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DUF4115 PF13464.6 ACL93856.2 - 0.0048 17.0 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4115) PapC_C PF13953.6 ACL93856.2 - 0.15 11.9 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 PapC C-terminal domain Glyco_transf_9 PF01075.17 ACL93857.1 - 1.9e-28 99.4 0.0 8.3e-28 97.3 0.0 1.7 1 1 1 2 2 2 1 Glycosyltransferase family 9 (heptosyltransferase) Amidohydro_1 PF01979.20 ACL93859.1 - 3.4e-21 76.0 0.0 3.4e-20 72.7 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ACL93859.1 - 7.9e-11 42.1 3.3 1e-06 28.5 0.5 2.5 2 1 0 2 2 2 2 Amidohydrolase family Urease_alpha PF00449.20 ACL93859.1 - 0.084 13.2 0.2 0.084 13.2 0.2 1.9 3 0 0 3 3 3 0 Urease alpha-subunit, N-terminal domain Sigma70_r4_2 PF08281.12 ACL93860.1 - 6.4e-09 35.4 0.1 1.3e-08 34.4 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 ACL93860.1 - 0.00017 21.3 1.9 0.00044 20.0 1.9 1.7 1 0 0 1 1 1 1 Sigma-70 region 2 TPR_2 PF07719.17 ACL93860.1 - 0.00054 19.9 0.1 0.00054 19.9 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 ACL93860.1 - 0.0014 18.6 1.2 0.011 15.9 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_21 PF09976.9 ACL93860.1 - 0.011 15.5 0.5 0.011 15.5 0.5 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_1 PF00515.28 ACL93860.1 - 0.02 14.7 3.4 0.026 14.3 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Sigma70_ECF PF07638.11 ACL93860.1 - 0.021 14.7 0.0 0.2 11.5 0.0 2.3 2 0 0 2 2 2 0 ECF sigma factor TPR_14 PF13428.6 ACL93860.1 - 0.051 14.4 2.2 0.051 14.4 2.2 5.1 4 2 1 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 ACL93860.1 - 0.14 12.5 0.2 0.14 12.5 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat YCII PF03795.14 ACL93861.2 - 2.2e-27 95.3 0.2 2.4e-27 95.2 0.2 1.0 1 0 0 1 1 1 1 YCII-related domain AMP-binding PF00501.28 ACL93862.1 - 8.6e-66 222.3 0.0 1e-65 222.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme HEAT_EZ PF13513.6 ACL93862.1 - 2.6 8.7 6.0 0.78 10.3 0.6 3.0 3 1 0 3 3 3 0 HEAT-like repeat YhhN PF07947.14 ACL93863.1 - 4.3e-23 81.9 14.8 4.3e-23 81.9 14.8 1.3 2 0 0 2 2 2 1 YhhN family TPP_enzyme_N PF02776.18 ACL93864.1 - 7.6e-37 126.6 1.2 5.7e-35 120.5 0.6 2.6 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 ACL93864.1 - 1.1e-28 100.0 5.9 1.8e-28 99.3 0.1 3.2 4 0 0 4 4 4 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 ACL93864.1 - 0.00063 19.5 0.4 0.055 13.2 0.1 2.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain YjeF_N PF03853.15 ACL93864.1 - 0.067 13.1 4.0 0.048 13.5 0.9 2.2 2 0 0 2 2 2 0 YjeF-related protein N-terminus Inhibitor_I69 PF13734.6 ACL93865.2 - 0.15 12.5 0.7 0.95 9.9 0.0 2.6 4 0 0 4 4 4 0 Spi protease inhibitor Lactamase_B PF00753.27 ACL93866.2 - 1e-34 120.3 0.1 1.4e-34 119.8 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ACL93866.2 - 0.00075 19.1 0.1 0.0026 17.3 0.0 1.9 2 1 0 2 2 2 1 Beta-lactamase superfamily domain BLACT_WH PF17778.1 ACL93866.2 - 0.041 13.9 0.4 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 Beta-lactamase associated winged helix domain MarR_2 PF12802.7 ACL93867.1 - 1e-14 54.1 0.9 2.3e-14 53.0 0.9 1.6 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 ACL93867.1 - 4.6e-10 39.8 0.0 8.2e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR PF01047.22 ACL93867.1 - 7.5e-09 35.4 0.0 1.9e-08 34.1 0.0 1.6 2 0 0 2 2 2 1 MarR family HTH_20 PF12840.7 ACL93867.1 - 0.037 14.1 0.5 0.11 12.6 0.5 1.9 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_IclR PF09339.10 ACL93867.1 - 0.049 13.4 0.3 0.11 12.3 0.1 1.7 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_34 PF13601.6 ACL93867.1 - 0.18 12.0 0.0 0.31 11.3 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain ECH_1 PF00378.20 ACL93868.1 - 8e-46 156.4 1.0 9.1e-46 156.2 1.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ACL93868.1 - 3.1e-25 89.4 1.6 1e-24 87.7 1.6 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase P4Ha_N PF08336.11 ACL93868.1 - 0.038 14.0 0.0 0.061 13.3 0.0 1.2 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region QRPTase_N PF02749.16 ACL93868.1 - 0.047 13.8 0.0 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain DUF3995 PF13160.6 ACL93869.1 - 1.7e-30 106.0 12.8 2e-30 105.7 12.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3995) adh_short PF00106.25 ACL93870.1 - 3.5e-27 95.1 0.1 5.5e-26 91.2 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ACL93870.1 - 4.4e-19 69.0 0.0 2.4e-18 66.6 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ACL93870.1 - 0.00024 21.1 0.2 0.00037 20.4 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ACL93870.1 - 0.0018 17.8 0.0 0.0039 16.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 ACL93872.1 - 5.5e-32 110.8 0.0 7.6e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ACL93872.1 - 6e-29 101.2 0.1 7.8e-29 100.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ACL93872.1 - 3.5e-05 23.8 0.2 5.4e-05 23.2 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_3 PF03447.16 ACL93872.1 - 0.041 14.5 1.2 9.2 7.0 0.1 2.2 1 1 1 2 2 2 0 Homoserine dehydrogenase, NAD binding domain DUF5126 PF17166.4 ACL93872.1 - 0.16 11.8 0.0 0.81 9.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5126) TfoX_N PF04993.13 ACL93873.2 - 2.8e-30 104.4 0.0 3.3e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 TfoX N-terminal domain Acetyltransf_1 PF00583.25 ACL93874.2 - 1.9e-16 60.4 0.0 2.3e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ACL93874.2 - 7.9e-08 32.3 0.0 1e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ACL93874.2 - 8.1e-07 29.4 0.0 1e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ACL93874.2 - 0.0021 18.0 0.0 0.0043 17.0 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_6 PF13480.7 ACL93874.2 - 0.0023 18.1 0.3 0.004 17.3 0.3 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain MFS_3 PF05977.13 ACL93875.2 - 1.5e-35 122.6 31.3 1.8e-35 122.3 31.3 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.16 ACL93875.2 - 7.5e-23 81.0 38.4 7.5e-23 81.0 38.4 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Acetyltransf_1 PF00583.25 ACL93877.1 - 7.5e-11 42.3 0.0 1e-10 41.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ACL93877.1 - 2e-06 28.1 0.0 3.3e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ACL93877.1 - 0.00062 19.9 0.0 0.00081 19.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ACL93877.1 - 0.0016 18.5 0.0 0.0055 16.8 0.0 1.8 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 ACL93877.1 - 0.0017 18.3 0.0 0.0022 17.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ACL93877.1 - 0.018 15.0 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein DUF1285 PF06938.11 ACL93878.1 - 8.3e-54 181.6 0.0 9.7e-54 181.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1285) NUDIX PF00293.28 ACL93879.1 - 4.4e-17 62.4 0.0 6.3e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain PolyA_pol PF01743.20 ACL93880.2 - 1.9e-24 86.5 0.2 3.1e-24 85.8 0.2 1.3 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 ACL93880.2 - 6.3e-08 32.3 0.5 1.4e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A DUF2336 PF10098.9 ACL93880.2 - 0.019 14.5 0.2 0.044 13.2 0.1 1.6 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2336) GATase PF00117.28 ACL93881.1 - 3e-16 59.7 0.0 3.9e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ACL93881.1 - 4.6e-05 23.3 0.1 0.0018 18.0 0.1 2.1 1 1 0 1 1 1 1 Peptidase C26 TPR_12 PF13424.6 ACL93882.2 - 2.6e-09 37.3 12.9 6.8e-08 32.7 4.9 3.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 ACL93882.2 - 2.4e-07 30.4 7.6 0.0071 16.4 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 ACL93882.2 - 3.8e-06 26.5 0.3 0.062 13.2 0.0 3.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 ACL93882.2 - 1e-05 25.1 1.7 0.096 12.0 0.5 2.3 1 1 1 2 2 2 2 MalT-like TPR region TPR_8 PF13181.6 ACL93882.2 - 1.3e-05 25.0 0.1 0.36 11.2 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 ACL93882.2 - 0.00015 21.6 10.5 0.52 10.5 0.2 4.2 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 ACL93882.2 - 0.0011 18.6 3.4 0.27 11.0 0.9 2.7 2 1 0 2 2 2 2 TPR repeat TPR_10 PF13374.6 ACL93882.2 - 0.0018 18.1 12.8 0.36 10.8 1.1 4.6 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_21 PF09976.9 ACL93882.2 - 0.0048 16.6 7.8 0.26 11.0 2.2 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat-like domain TPR_19 PF14559.6 ACL93882.2 - 0.053 14.0 12.3 0.058 13.9 4.5 3.6 2 1 2 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.9 ACL93882.2 - 0.096 12.4 0.1 0.22 11.2 0.1 1.5 1 0 0 1 1 1 0 26S proteasome subunit RPN7 MelC1 PF06236.11 ACL93882.2 - 1.1 9.3 7.8 2.2 8.4 3.9 2.5 2 0 0 2 2 2 0 Tyrosinase co-factor MelC1 TPR_14 PF13428.6 ACL93882.2 - 1.8 9.6 25.9 0.56 11.2 2.9 5.1 1 1 3 4 4 4 0 Tetratricopeptide repeat DUF4164 PF13747.6 ACL93882.2 - 3 8.2 9.0 3 8.2 6.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) TPR_16 PF13432.6 ACL93882.2 - 7 7.4 33.6 0.16 12.7 2.7 4.2 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 ACL93882.2 - 7.6 7.4 7.5 23 5.9 0.6 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat PepSY_TM PF03929.16 ACL93883.1 - 4.6 6.8 7.8 0.97 9.0 1.3 2.2 2 0 0 2 2 2 0 PepSY-associated TM region DUF3040 PF11239.8 ACL93883.1 - 8.2 6.8 15.1 1.6 9.1 10.0 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3040) DUF4870 PF09685.10 ACL93884.2 - 0.00052 20.1 3.6 0.00068 19.7 3.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4870) SUR7 PF06687.12 ACL93884.2 - 0.00056 19.6 0.8 0.00064 19.4 0.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family SLATT_fungal PF18142.1 ACL93884.2 - 0.89 9.6 2.5 0.98 9.4 0.0 2.0 1 1 2 3 3 3 0 SMODS and SLOG-associating 2TM effector domain OAD_gamma PF04277.13 ACL93884.2 - 7.3 7.3 6.5 0.85 10.3 1.2 2.2 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Fasciclin PF02469.22 ACL93886.1 - 2.5e-33 115.0 0.0 3e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain DUF3948 PF13134.6 ACL93886.1 - 0.17 11.6 1.4 0.51 10.1 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3948) FolB PF02152.18 ACL93888.2 - 1.5e-27 96.3 0.1 1.8e-27 96.1 0.1 1.1 1 0 0 1 1 1 1 Dihydroneopterin aldolase adh_short_C2 PF13561.6 ACL93889.1 - 2.6e-35 122.1 0.1 2.9e-35 121.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ACL93889.1 - 7.5e-32 110.4 0.0 1e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ACL93889.1 - 4.4e-06 26.7 0.1 7.5e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ACL93889.1 - 0.0012 18.4 0.0 0.0018 17.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ACL93889.1 - 0.021 14.2 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Glyco_hydro_20b PF02838.15 ACL93889.1 - 0.093 13.5 1.7 1.6 9.5 0.1 2.8 2 1 1 3 3 3 0 Glycosyl hydrolase family 20, domain 2 NUDIX PF00293.28 ACL93890.1 - 4.5e-20 72.0 0.3 5.5e-20 71.8 0.3 1.1 1 0 0 1 1 1 1 NUDIX domain TrkA_C PF02080.21 ACL93890.1 - 0.014 15.2 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-C domain Aldedh PF00171.22 ACL93891.1 - 2.2e-150 501.2 3.5 2.5e-150 501.0 3.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family 3HCDH PF00725.22 ACL93891.1 - 0.042 14.5 0.1 1.3 9.7 0.1 2.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DUF559 PF04480.12 ACL93893.1 - 7.2e-47 157.8 0.0 7.9e-47 157.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF559) MTES_1575 PF18741.1 ACL93893.1 - 1.4e-11 44.4 0.0 2.4e-11 43.7 0.0 1.4 1 1 1 2 2 2 1 REase_MTES_1575 DUF3606 PF12244.8 ACL93895.1 - 2.9e-19 68.7 0.2 3.5e-19 68.5 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3606) AsnC_trans_reg PF01037.21 ACL93899.1 - 1.4e-20 73.0 0.0 2.2e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_AsnC-type PF13404.6 ACL93899.1 - 1.2e-18 66.7 1.1 1.9e-18 66.0 1.1 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 ACL93899.1 - 1.3e-18 66.3 0.1 1.9e-18 65.8 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 ACL93899.1 - 6.8e-05 22.7 0.7 0.00013 21.8 0.7 1.4 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 ACL93899.1 - 0.00017 21.6 0.1 0.0003 20.8 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 ACL93899.1 - 0.00042 20.2 0.3 0.00076 19.4 0.0 1.5 2 0 0 2 2 2 1 HTH domain HTH_Crp_2 PF13545.6 ACL93899.1 - 0.00082 19.3 0.3 0.0014 18.6 0.3 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Rrf2 PF02082.20 ACL93899.1 - 0.0042 17.4 0.0 0.0085 16.4 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator MarR PF01047.22 ACL93899.1 - 0.043 13.7 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 MarR family TrmB PF01978.19 ACL93899.1 - 0.045 13.7 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_27 PF13463.6 ACL93899.1 - 0.063 13.8 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain NTS_2 PF15448.6 ACL93899.1 - 0.22 11.9 0.0 0.55 10.7 0.0 1.6 2 0 0 2 2 2 0 N-terminal segments of P. falciparum erythrocyte membrane protein Cons_hypoth698 PF03601.14 ACL93901.1 - 1.1e-77 260.9 21.8 1.5e-77 260.5 21.8 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 698 AA_permease_2 PF13520.6 ACL93902.2 - 7.7e-55 186.4 39.9 9.4e-55 186.1 39.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ACL93902.2 - 6.9e-35 120.5 36.3 8.2e-35 120.3 36.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 ACL93902.2 - 8.7e-06 25.7 2.2 8.7e-06 25.7 2.2 4.0 5 0 0 5 5 5 1 C-terminus of AA_permease Spore_permease PF03845.13 ACL93902.2 - 0.035 12.9 19.1 0.33 9.7 17.8 2.6 1 1 0 1 1 1 0 Spore germination protein Acyl-CoA_dh_1 PF00441.24 ACL93903.1 - 3.4e-47 160.4 3.9 5.7e-47 159.7 3.9 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ACL93903.1 - 7.1e-31 107.2 0.3 2.6e-30 105.4 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ACL93903.1 - 2.6e-29 101.3 0.0 4.7e-29 100.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ACL93903.1 - 1.6e-23 83.5 3.6 3.2e-23 82.5 3.6 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MCPsignal PF00015.21 ACL93904.1 - 5.2e-53 179.4 36.0 7e-53 179.0 20.8 3.1 3 1 1 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Protoglobin PF11563.8 ACL93904.1 - 5.9e-42 143.3 0.0 1.4e-41 142.1 0.0 1.6 1 0 0 1 1 1 1 Protoglobin HAMP PF00672.25 ACL93904.1 - 0.0016 18.8 2.2 0.0068 16.8 0.1 3.3 2 1 0 2 2 2 1 HAMP domain Laminin_II PF06009.12 ACL93904.1 - 0.038 14.0 12.9 0.13 12.3 1.2 3.2 3 0 0 3 3 3 0 Laminin Domain II BLOC1_2 PF10046.9 ACL93904.1 - 0.042 14.2 10.0 2.5 8.5 0.1 4.4 2 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tox-URI2 PF15653.6 ACL93904.1 - 0.045 14.0 0.5 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 URI fold toxin 2 DUF1664 PF07889.12 ACL93904.1 - 0.092 12.8 9.1 6.3 6.9 0.2 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Sec8_exocyst PF04048.14 ACL93904.1 - 0.1 12.5 3.0 35 4.3 0.0 3.6 2 2 1 3 3 3 0 Sec8 exocyst complex component specific domain Syntaxin_2 PF14523.6 ACL93904.1 - 1.3 9.4 7.8 8.9 6.7 1.4 3.6 3 2 1 4 4 4 0 Syntaxin-like protein Nup54 PF13874.6 ACL93904.1 - 1.4 9.1 12.4 2.4 8.3 0.2 3.6 4 0 0 4 4 4 0 Nucleoporin complex subunit 54 DUF948 PF06103.11 ACL93904.1 - 1.6 9.0 18.1 7.8 6.8 0.7 4.4 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF3450 PF11932.8 ACL93904.1 - 6.6 6.0 21.6 7.9 5.7 0.3 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3450) TonB_C PF03544.14 ACL93905.2 - 0.0028 18.1 0.0 0.0064 16.9 0.0 1.6 2 0 0 2 2 2 1 Gram-negative bacterial TonB protein C-terminal PCSK9_C3 PF18463.1 ACL93905.2 - 0.054 13.7 0.2 0.077 13.2 0.2 1.2 1 0 0 1 1 1 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain Rhodopsin_N PF10413.9 ACL93905.2 - 0.18 11.7 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Amino terminal of the G-protein receptor rhodopsin MCPsignal PF00015.21 ACL93906.1 - 2.2e-56 190.3 21.4 2.2e-56 190.3 21.4 4.8 3 2 2 5 5 5 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 ACL93906.1 - 4.6e-08 33.3 3.7 0.00048 20.4 0.0 4.6 3 1 0 3 3 3 2 HAMP domain BLOC1_2 PF10046.9 ACL93906.1 - 0.044 14.1 10.7 5 7.5 0.1 5.4 4 1 1 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HXXSHH PF07586.11 ACL93906.1 - 0.088 12.4 0.0 0.088 12.4 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1552) Serine_rich PF08824.10 ACL93906.1 - 0.25 11.3 4.2 0.59 10.1 0.4 3.1 2 1 1 3 3 3 0 Serine rich protein interaction domain DUF948 PF06103.11 ACL93906.1 - 0.48 10.7 28.7 0.074 13.3 0.8 6.2 4 3 3 7 7 7 0 Bacterial protein of unknown function (DUF948) T2SSF PF00482.23 ACL93906.1 - 2.3 8.2 16.1 0.22 11.5 0.6 4.3 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein F Sec8_exocyst PF04048.14 ACL93906.1 - 3.1 7.7 11.6 4.4 7.2 0.0 4.7 4 1 1 5 5 5 0 Sec8 exocyst complex component specific domain STAS_2 PF13466.6 ACL93907.2 - 2.3e-13 50.3 0.1 2.7e-13 50.1 0.1 1.1 1 0 0 1 1 1 1 STAS domain Response_reg PF00072.24 ACL93908.1 - 2.2e-28 98.7 0.0 2.4e-28 98.5 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain FleQ PF06490.11 ACL93908.1 - 0.018 15.4 0.0 0.024 15.0 0.0 1.2 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ Glycos_transf_1 PF00534.20 ACL93908.1 - 0.097 12.2 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 CheW PF01584.19 ACL93909.1 - 1.5e-22 79.7 2.9 1.7e-22 79.5 1.5 1.9 2 0 0 2 2 2 1 CheW-like domain HATPase_c PF02518.26 ACL93909.1 - 1.9e-19 70.2 0.1 5.4e-19 68.8 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Hpt PF01627.23 ACL93909.1 - 9e-19 67.5 4.5 1.2e-16 60.7 2.4 3.1 2 1 1 3 3 3 2 Hpt domain H-kinase_dim PF02895.14 ACL93909.1 - 1.6e-17 63.6 0.3 4.1e-17 62.3 0.3 1.7 1 0 0 1 1 1 1 Signal transducing histidine kinase, homodimeric domain LeuA_dimer PF08502.10 ACL93909.1 - 0.12 12.3 0.0 30 4.5 0.0 2.9 2 0 0 2 2 2 0 LeuA allosteric (dimerisation) domain CheW PF01584.19 ACL93910.1 - 5.8e-35 119.9 0.4 6.6e-35 119.7 0.4 1.0 1 0 0 1 1 1 1 CheW-like domain CheR PF01739.18 ACL93911.1 - 2.1e-66 223.2 0.0 2.6e-66 222.8 0.0 1.1 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain CheR_N PF03705.15 ACL93911.1 - 2.3e-17 62.5 0.1 3.7e-17 61.8 0.1 1.4 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain Methyltransf_12 PF08242.12 ACL93911.1 - 0.00016 22.4 0.0 0.0035 18.1 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ACL93911.1 - 0.00075 20.2 0.0 0.043 14.5 0.0 3.1 2 2 1 4 4 4 1 Methyltransferase domain Methyltransf_11 PF08241.12 ACL93911.1 - 0.0083 16.7 0.0 0.13 12.9 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Strep_pep PF14404.6 ACL93911.1 - 0.077 13.3 0.0 0.29 11.5 0.0 2.0 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Streptomyces species CheB_methylest PF01339.17 ACL93912.1 - 1.1e-58 197.7 0.3 2.5e-58 196.5 0.3 1.6 1 0 0 1 1 1 1 CheB methylesterase Response_reg PF00072.24 ACL93912.1 - 2.6e-24 85.5 0.1 5.7e-24 84.4 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Response_reg PF00072.24 ACL93913.1 - 4.6e-27 94.4 0.0 5.1e-27 94.2 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain FdhD-NarQ PF02634.15 ACL93913.1 - 0.17 11.6 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 FdhD/NarQ family CheD PF03975.13 ACL93914.1 - 8.9e-30 103.0 0.0 1.3e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 CheD chemotactic sensory transduction Response_reg PF00072.24 ACL93916.1 - 2.3e-22 79.3 0.0 2.9e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain DUF3868 PF12984.7 ACL93916.1 - 0.17 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3868) Plug PF07715.15 ACL93918.1 - 2.5e-14 53.7 0.5 6.8e-14 52.3 0.5 1.8 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain Amidohydro_1 PF01979.20 ACL93919.1 - 1.4e-22 80.5 0.1 1.7e-22 80.2 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ACL93919.1 - 2e-09 37.4 1.5 4.8e-07 29.6 0.1 2.4 2 0 0 2 2 2 2 Amidohydrolase family SIS PF01380.22 ACL93920.1 - 6.3e-32 110.2 2.6 2.4e-16 59.8 1.0 2.2 2 0 0 2 2 2 2 SIS domain SIS_2 PF13580.6 ACL93920.1 - 0.015 15.3 0.1 0.015 15.3 0.1 2.9 2 2 1 3 3 3 0 SIS domain Rnf-Nqr PF02508.14 ACL93920.1 - 0.21 11.6 0.5 0.44 10.5 0.5 1.5 1 1 0 1 1 1 0 Rnf-Nqr subunit, membrane protein UTRA PF07702.13 ACL93921.1 - 1.1e-37 129.1 0.1 1.9e-37 128.3 0.1 1.4 1 0 0 1 1 1 1 UTRA domain GntR PF00392.21 ACL93921.1 - 5.5e-21 74.0 0.8 1e-20 73.1 0.1 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_DeoR PF08220.12 ACL93921.1 - 0.0021 17.8 0.1 0.0039 16.9 0.1 1.4 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain MarR_2 PF12802.7 ACL93921.1 - 0.0034 17.2 0.2 0.023 14.5 0.0 2.5 2 0 0 2 2 2 1 MarR family HTH_41 PF14502.6 ACL93921.1 - 0.0074 16.0 0.0 0.026 14.2 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 ACL93921.1 - 0.019 14.9 0.1 0.061 13.3 0.1 1.9 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Rrf2 PF02082.20 ACL93921.1 - 0.029 14.7 0.0 0.057 13.8 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator MarR PF01047.22 ACL93921.1 - 0.031 14.2 0.0 0.082 12.9 0.0 1.7 1 0 0 1 1 1 0 MarR family HTH_11 PF08279.12 ACL93921.1 - 0.066 13.2 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 HTH domain HTH_28 PF13518.6 ACL93921.1 - 0.069 13.3 0.8 2.1 8.5 0.0 2.9 3 0 0 3 3 2 0 Helix-turn-helix domain TrmB PF01978.19 ACL93921.1 - 0.081 12.8 0.0 0.25 11.3 0.0 1.8 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB TonB_dep_Rec PF00593.24 ACL93922.1 - 9.5e-47 160.9 31.2 9.5e-47 160.9 31.2 2.2 1 1 0 2 2 2 1 TonB dependent receptor OMP_b-brl_3 PF14905.6 ACL93922.1 - 7e-17 61.5 8.1 7e-17 61.5 8.1 2.1 2 0 0 2 2 2 1 Outer membrane protein beta-barrel family Plug PF07715.15 ACL93922.1 - 6.3e-15 55.7 1.6 5.1e-14 52.8 0.1 2.9 3 0 0 3 3 3 1 TonB-dependent Receptor Plug Domain Glyco_hydro_20 PF00728.22 ACL93923.1 - 3e-122 408.4 0.1 3.6e-122 408.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 ACL93923.1 - 1.6e-19 70.9 0.2 1.1e-18 68.2 0.1 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 CHB_HEX_C_1 PF13290.6 ACL93923.1 - 7.7e-11 41.8 0.1 1.8e-10 40.7 0.1 1.5 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.6 ACL93923.1 - 1e-08 35.2 0.0 1.9e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Fn3 associated CHB_HEX_C PF03174.13 ACL93923.1 - 0.07 13.1 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain PEP-utilizers_C PF02896.18 ACL93924.1 - 5.5e-98 327.7 0.0 8.1e-98 327.2 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PTS_EIIA_1 PF00358.20 ACL93924.1 - 4.9e-42 142.7 0.0 1.2e-41 141.4 0.0 1.7 2 0 0 2 2 2 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 PTS-HPr PF00381.19 ACL93924.1 - 1.6e-23 82.8 0.1 4.5e-23 81.3 0.1 1.9 1 0 0 1 1 1 1 PTS HPr component phosphorylation site PEP-utilisers_N PF05524.13 ACL93924.1 - 1.4e-20 73.6 4.4 1.4e-20 73.6 4.4 3.2 3 0 0 3 3 3 1 PEP-utilising enzyme, N-terminal PEP-utilizers PF00391.23 ACL93924.1 - 8.7e-20 70.2 1.9 4.3e-19 68.0 1.0 2.7 2 0 0 2 2 2 1 PEP-utilising enzyme, mobile domain HpcH_HpaI PF03328.14 ACL93924.1 - 3.8e-06 26.2 0.1 3.8e-06 26.2 0.1 2.8 4 0 0 4 4 4 1 HpcH/HpaI aldolase/citrate lyase family Biotin_lipoyl_2 PF13533.6 ACL93924.1 - 0.00025 20.8 0.2 0.016 15.1 0.0 3.3 3 0 0 3 3 3 1 Biotin-lipoyl like Peptidase_M23 PF01551.22 ACL93924.1 - 0.057 13.6 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 Peptidase family M23 PTS_EIIC PF02378.18 ACL93925.1 - 3.3e-70 236.7 26.8 3.3e-70 236.7 26.8 1.5 2 0 0 2 2 2 1 Phosphotransferase system, EIIC PTS_EIIB PF00367.20 ACL93925.1 - 1.5e-21 75.6 1.0 4e-11 42.2 0.2 2.5 2 0 0 2 2 2 2 phosphotransferase system, EIIB DUF4072 PF13284.6 ACL93925.1 - 0.17 12.3 9.9 1.3 9.5 2.5 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4072) Na_H_antiport_1 PF06965.12 ACL93926.1 - 3.5e-143 477.0 28.4 4e-143 476.8 28.4 1.0 1 0 0 1 1 1 1 Na+/H+ antiporter 1 Bac_transf PF02397.16 ACL93929.1 - 2.3e-06 27.4 0.0 2.5e-06 27.2 0.0 1.0 1 0 0 1 1 1 1 Bacterial sugar transferase DivIC PF04977.15 ACL93929.1 - 0.14 11.9 0.1 0.21 11.4 0.1 1.3 1 1 0 1 1 1 0 Septum formation initiator GLF PF03275.13 ACL93930.3 - 5.6e-82 274.4 4.3 7.7e-82 274.0 4.3 1.2 1 0 0 1 1 1 1 UDP-galactopyranose mutase NAD_binding_8 PF13450.6 ACL93930.3 - 1.7e-15 56.9 0.0 4.1e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 ACL93930.3 - 3.4e-05 23.4 0.0 0.0041 16.5 0.0 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 ACL93930.3 - 6e-05 23.5 0.0 0.005 17.4 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ACL93930.3 - 9.1e-05 22.5 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding HI0933_like PF03486.14 ACL93930.3 - 0.0012 17.6 0.0 0.21 10.2 0.0 2.7 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.24 ACL93930.3 - 0.0016 18.1 0.0 0.0028 17.3 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ACL93930.3 - 0.0063 15.8 0.0 0.016 14.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 ACL93930.3 - 0.034 13.5 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 GMC oxidoreductase Lycopene_cycl PF05834.12 ACL93930.3 - 0.035 13.2 0.1 0.056 12.5 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 ACL93930.3 - 0.074 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Sacchrp_dh_NADP PF03435.18 ACL93930.3 - 0.11 12.8 0.2 0.22 11.8 0.0 1.6 2 0 0 2 2 1 0 Saccharopine dehydrogenase NADP binding domain DUF1188 PF06690.11 ACL93930.3 - 0.17 11.4 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) Thi4 PF01946.17 ACL93930.3 - 0.17 11.1 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 ACL93930.3 - 0.19 12.0 0.0 0.41 10.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Glycos_transf_1 PF00534.20 ACL93931.1 - 2.5e-14 53.2 0.0 3.8e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ACL93931.1 - 5.5e-14 52.7 0.2 1.3e-13 51.5 0.1 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Polysacc_synt PF01943.17 ACL93932.1 - 7.7e-43 146.8 31.3 3.8e-42 144.6 17.2 2.0 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein Polysacc_synt_3 PF13440.6 ACL93932.1 - 3.2e-13 49.6 12.8 3.2e-13 49.6 12.8 1.8 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein Polysacc_synt_C PF14667.6 ACL93932.1 - 1e-07 32.1 6.6 1e-07 32.1 6.6 4.2 3 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Glycos_transf_1 PF00534.20 ACL93934.2 - 1.7e-26 92.8 0.0 3.8e-26 91.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ACL93934.2 - 5.2e-23 82.0 0.0 1.2e-22 80.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ACL93934.2 - 7.6e-06 26.0 0.0 2.2e-05 24.5 0.0 1.8 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 ACL93934.2 - 1.4e-05 25.3 0.0 4.9e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 PsbN PF02468.15 ACL93935.1 - 0.68 9.8 0.0 0.68 9.8 0.0 3.5 3 0 0 3 3 3 0 Photosystem II reaction centre N protein (psbN) Epimerase PF01370.21 ACL93936.1 - 1.4e-69 234.2 0.0 1.7e-69 234.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ACL93936.1 - 1.5e-14 54.1 0.0 3.2e-13 49.8 0.0 2.3 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 ACL93936.1 - 7e-09 35.2 0.0 1.3e-08 34.3 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 ACL93936.1 - 0.00067 18.9 0.0 0.0066 15.6 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 ACL93936.1 - 0.03 14.2 0.0 0.28 11.0 0.0 2.5 2 2 1 3 3 3 0 NAD(P)H-binding adh_short_C2 PF13561.6 ACL93936.1 - 0.085 12.4 0.2 2.1 7.8 0.0 2.4 3 0 0 3 3 3 0 Enoyl-(Acyl carrier protein) reductase GDP_Man_Dehyd PF16363.5 ACL93937.1 - 1.1e-159 531.2 0.0 1.3e-159 531.0 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ACL93937.1 - 5.8e-74 248.6 0.1 7.3e-74 248.3 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ACL93937.1 - 3.7e-08 32.8 0.0 5.9e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 ACL93937.1 - 0.00073 18.8 0.0 0.0011 18.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 ACL93937.1 - 0.082 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Cytochrome-c551 PF10643.9 ACL93938.1 - 0.11 12.1 0.2 0.2 11.2 0.1 1.5 1 1 1 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 TrwC PF08751.11 ACL93939.1 - 2.2e-86 290.0 11.9 8e-86 288.2 11.9 2.0 1 0 0 1 1 1 1 TrwC relaxase AAA_30 PF13604.6 ACL93939.1 - 4.7e-45 153.7 12.5 4.7e-45 153.7 12.5 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 ACL93939.1 - 1.1e-10 42.0 4.1 1.5e-10 41.6 0.9 2.7 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 ACL93939.1 - 1.9e-06 27.8 0.7 0.00064 19.5 0.3 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 ACL93939.1 - 0.00049 19.9 1.2 0.00049 19.9 1.2 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_11 PF13086.6 ACL93939.1 - 0.0077 16.1 4.2 0.2 11.4 0.1 3.0 2 1 1 3 3 3 2 AAA domain CusF_Ec PF11604.8 ACL93939.1 - 0.055 13.4 0.3 1.5 8.8 0.0 3.5 3 1 0 3 3 3 0 Copper binding periplasmic protein CusF SH3_13 PF18335.1 ACL93939.1 - 0.058 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain PIF1 PF05970.14 ACL93939.1 - 0.073 12.2 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 PIF1-like helicase TrwB_AAD_bind PF10412.9 ACL93940.1 - 6e-113 377.6 0.0 7.4e-113 377.4 0.0 1.1 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain TraG-D_C PF12696.7 ACL93940.1 - 2.8e-21 75.8 0.0 5.3e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG T4SS-DNA_transf PF02534.14 ACL93940.1 - 7.4e-21 74.5 0.0 3.8e-13 49.1 0.0 2.0 2 0 0 2 2 2 2 Type IV secretory system Conjugative DNA transfer DUF87 PF01935.17 ACL93940.1 - 2.1e-07 31.3 0.0 3.2e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_16 PF13191.6 ACL93940.1 - 3.7e-05 24.2 2.3 0.00031 21.2 0.7 2.7 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 ACL93940.1 - 0.00025 21.3 0.1 0.0014 18.9 0.1 2.3 2 1 0 2 2 1 1 AAA domain T2SSE PF00437.20 ACL93940.1 - 0.0015 17.6 0.1 0.0025 16.9 0.1 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 ACL93940.1 - 0.0026 17.2 0.0 0.005 16.2 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family DUF853 PF05872.12 ACL93940.1 - 0.0054 15.4 0.0 0.0085 14.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) Zeta_toxin PF06414.12 ACL93940.1 - 0.0063 15.8 0.0 0.35 10.1 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin Pox_A32 PF04665.12 ACL93940.1 - 0.0073 15.8 0.0 0.32 10.4 0.0 2.2 2 0 0 2 2 2 1 Poxvirus A32 protein AAA_19 PF13245.6 ACL93940.1 - 0.016 15.6 0.2 0.071 13.5 0.1 2.1 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.6 ACL93940.1 - 0.016 15.5 0.2 0.043 14.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ACL93940.1 - 0.026 15.0 0.0 0.063 13.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 ACL93940.1 - 0.03 14.1 0.0 0.07 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ACL93940.1 - 0.032 13.8 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SRP54 PF00448.22 ACL93940.1 - 0.037 13.6 0.1 0.069 12.8 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain G-alpha PF00503.20 ACL93940.1 - 0.081 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit NACHT PF05729.12 ACL93940.1 - 0.082 12.8 0.5 0.29 11.0 0.0 2.1 3 0 0 3 3 2 0 NACHT domain AAA_14 PF13173.6 ACL93940.1 - 0.084 12.9 0.0 0.31 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 ACL93940.1 - 0.19 11.5 0.1 0.28 10.9 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ACL93940.1 - 0.22 11.7 1.4 0.99 9.6 0.2 2.6 2 1 0 2 2 2 0 AAA domain DUF3422 PF11902.8 ACL93941.1 - 0.0015 17.7 0.7 0.0018 17.5 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3422) CRIC_ras_sig PF10534.9 ACL93941.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Connector enhancer of kinase suppressor of ras HTH_17 PF12728.7 ACL93942.1 - 2.8e-05 24.2 0.0 3.1e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 ACL93944.1 - 1.7e-08 34.7 3.2 2.5e-08 34.1 3.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 ACL93944.1 - 0.0006 19.8 0.0 0.00088 19.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 ACL93944.1 - 0.0043 17.1 0.2 0.0065 16.5 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix Arm-DNA-bind_3 PF13356.6 ACL93945.2 - 8e-17 61.4 0.4 2.8e-16 59.6 0.4 2.0 1 0 0 1 1 1 1 Arm DNA-binding domain Phage_integrase PF00589.22 ACL93945.2 - 2.5e-11 43.7 0.0 4.4e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family HTH_31 PF13560.6 ACL93946.3 - 1.2e-09 38.3 7.7 1.5e-09 38.0 7.7 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 ACL93946.3 - 5.2e-06 26.4 0.1 7.1e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_37 PF13744.6 ACL93946.3 - 0.00068 19.5 0.1 0.00086 19.2 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 ACL93946.3 - 0.0018 18.1 0.3 0.003 17.4 0.1 1.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 ACL93946.3 - 0.0022 18.0 0.0 0.0027 17.7 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain MqsA_antitoxin PF15731.5 ACL93946.3 - 0.0058 16.7 0.1 0.0062 16.7 0.1 1.1 1 0 0 1 1 1 1 Antitoxin component of bacterial toxin-antitoxin system, MqsA HipA_C PF07804.12 ACL93947.1 - 1.1e-51 175.5 0.0 1.5e-51 175.1 0.0 1.1 1 0 0 1 1 1 1 HipA-like C-terminal domain Couple_hipA PF13657.6 ACL93947.1 - 1.7e-22 79.9 0.0 3.5e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 HipA N-terminal domain Lactamase_B PF00753.27 ACL93948.1 - 3.6e-29 102.2 2.2 5.3e-29 101.6 2.2 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily PseudoU_synth_2 PF00849.22 ACL93950.1 - 7.8e-32 110.6 0.0 1e-31 110.2 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 ACL93950.1 - 7.1e-06 25.6 0.2 2.5e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 S4 domain TonB_dep_Rec PF00593.24 ACL93951.1 - 3.8e-45 155.7 26.7 4.1e-44 152.3 14.6 2.1 2 0 0 2 2 2 2 TonB dependent receptor Plug PF07715.15 ACL93951.1 - 2.7e-15 56.9 0.4 6.5e-15 55.6 0.4 1.7 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 ACL93951.1 - 0.00022 20.3 0.1 0.11 11.5 0.0 2.3 2 0 0 2 2 2 2 Outer membrane protein beta-barrel family CBP_BcsO PF17037.5 ACL93951.1 - 0.16 12.1 0.0 0.43 10.7 0.0 1.6 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO PhoD PF09423.10 ACL93952.1 - 5.3e-121 403.9 1.2 6.3e-121 403.7 1.2 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 ACL93952.1 - 4.4e-28 97.7 0.4 1.2e-27 96.3 0.4 1.8 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 ACL93952.1 - 0.0032 18.0 0.8 0.006 17.1 0.1 1.9 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain LysE PF01810.18 ACL93953.1 - 3.3e-33 114.8 6.8 4.1e-33 114.5 6.8 1.0 1 0 0 1 1 1 1 LysE type translocator TerC PF03741.16 ACL93953.1 - 0.015 15.0 0.7 0.015 15.0 0.7 1.6 1 1 1 2 2 2 0 Integral membrane protein TerC family PRA-CH PF01502.18 ACL93954.1 - 1e-33 115.0 0.0 1.5e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase GnsAB_toxin PF08178.11 ACL93954.1 - 0.014 15.3 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system DUF817 PF05675.12 ACL93955.2 - 6e-106 353.4 16.1 6.9e-106 353.2 16.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF817) GTP_cyclohydroI PF01227.22 ACL93956.1 - 8.4e-73 243.6 0.0 9.7e-73 243.4 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 ACL93956.1 - 0.0052 16.9 0.0 0.0081 16.3 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein tRNA-synt_1e PF01406.19 ACL93957.1 - 1.6e-115 385.6 0.0 2e-115 385.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DALR_2 PF09190.11 ACL93957.1 - 2.3e-12 47.2 1.8 3.7e-12 46.5 0.7 1.9 2 0 0 2 2 2 1 DALR domain tRNA-synt_1g PF09334.11 ACL93957.1 - 1.8e-11 43.5 0.0 6.5e-06 25.1 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1f PF01921.18 ACL93957.1 - 3.4e-07 29.5 0.0 0.00044 19.3 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (K) tRNA-synt_1 PF00133.22 ACL93957.1 - 5.6e-07 28.2 0.0 1.2e-06 27.1 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Polyketide_cyc2 PF10604.9 ACL93958.1 - 2.8e-08 34.1 0.5 3.3e-08 33.9 0.5 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 ACL93958.1 - 7.2e-08 32.7 0.9 2.4e-07 31.0 0.9 1.8 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 ACL93958.1 - 0.0057 16.9 0.7 0.0069 16.6 0.7 1.3 1 1 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein NifU_N PF01592.16 ACL93959.1 - 2.6e-06 27.6 0.0 3.2e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain YidD PF01809.18 ACL93960.1 - 2.7e-25 88.0 0.1 3.2e-25 87.8 0.1 1.1 1 0 0 1 1 1 1 Putative membrane protein insertion efficiency factor tRNA-synt_2b PF00587.25 ACL93961.1 - 7.8e-41 140.0 0.0 1.4e-40 139.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 ACL93961.1 - 2.8e-19 69.0 0.8 6.4e-19 67.9 0.8 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 ACL93961.1 - 1.4e-16 60.3 0.0 2.7e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 ACL93961.1 - 1.1e-07 31.7 0.0 1e-06 28.7 0.0 2.4 2 0 0 2 2 2 1 TGS domain Glyco_tranf_2_3 PF13641.6 ACL93962.1 - 6.6e-19 68.7 0.0 9.8e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 ACL93962.1 - 2e-17 63.5 0.0 3e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 ACL93962.1 - 1.8e-05 24.4 0.0 0.002 17.7 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 ACL93962.1 - 2.1e-05 24.1 0.0 3.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_trans_2_3 PF13632.6 ACL93962.1 - 0.015 15.2 0.0 0.062 13.2 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 ACL93962.1 - 0.024 14.1 0.0 0.052 13.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 21 HMGL-like PF00682.19 ACL93965.1 - 2.1e-44 152.0 0.3 2.5e-44 151.8 0.3 1.0 1 0 0 1 1 1 1 HMGL-like PMT PF02366.18 ACL93966.1 - 1.9e-06 27.7 15.5 5.3e-06 26.2 15.5 1.7 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF1478 PF07349.11 ACL93966.1 - 0.0062 16.4 3.5 0.084 12.8 0.2 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1478) DUF937 PF06078.11 ACL93966.1 - 0.048 14.3 2.1 1.4 9.5 0.1 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF937) Glycos_transf_2 PF00535.26 ACL93967.1 - 1.4e-23 83.5 0.0 2.2e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ACL93967.1 - 3.7e-07 30.3 0.0 4.4e-07 30.0 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 ACL93967.1 - 0.016 14.7 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Pox_A14 PF05767.12 ACL93968.2 - 0.014 15.6 2.4 0.014 15.6 2.4 1.8 1 1 0 1 1 1 0 Poxvirus virion envelope protein A14 Pex26 PF07163.12 ACL93968.2 - 0.11 11.8 2.8 0.12 11.6 2.8 1.1 1 0 0 1 1 1 0 Pex26 protein DUF3043 PF11241.8 ACL93968.2 - 4 7.4 7.3 0.64 10.0 2.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3043) SpoU_methylase PF00588.19 ACL93969.1 - 2.6e-30 105.5 0.0 2.9e-30 105.3 0.0 1.0 1 0 0 1 1 1 1 SpoU rRNA Methylase family UCR_Fe-S_N PF10399.9 ACL93970.1 - 1.4e-19 69.2 0.3 2.4e-19 68.4 0.3 1.4 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Rieske PF00355.26 ACL93970.1 - 1.7e-12 47.1 0.0 3.3e-12 46.2 0.0 1.4 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain TAT_signal PF10518.9 ACL93970.1 - 0.00055 19.7 0.2 0.0016 18.2 0.2 1.8 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence Cytochrome_B PF00033.19 ACL93971.1 - 2.5e-75 252.4 18.8 2.5e-75 252.4 18.8 1.8 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 ACL93971.1 - 2.1e-42 145.0 16.4 2.2e-42 145.0 12.1 2.5 3 0 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 ACL93971.1 - 2.4e-38 130.6 1.6 2.4e-38 130.6 1.6 3.6 3 2 0 4 4 4 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_C1 PF02167.15 ACL93972.1 - 2.5e-96 321.6 0.0 2.9e-96 321.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrom_C PF00034.21 ACL93972.1 - 0.00013 23.1 0.2 0.021 15.9 0.1 2.5 2 1 0 2 2 2 2 Cytochrome c Cytochrome_CBB3 PF13442.6 ACL93972.1 - 0.0034 17.7 0.0 0.0083 16.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Asp_protease_2 PF13650.6 ACL93973.1 - 3.8e-05 24.3 2.4 0.094 13.4 0.8 3.1 2 1 0 2 2 2 2 Aspartyl protease His_Phos_1 PF00300.22 ACL93974.1 - 1.8e-16 60.4 1.1 3.5e-13 49.7 0.3 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) MutL PF13941.6 ACL93974.1 - 0.011 14.4 2.7 0.013 14.1 2.7 1.1 1 0 0 1 1 1 0 MutL protein Pilus_CpaD PF09476.10 ACL93974.1 - 0.056 13.2 1.2 0.074 12.8 1.2 1.2 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) acVLRF1 PF18859.1 ACL93974.1 - 0.13 12.5 2.4 11 6.4 0.1 2.1 2 0 0 2 2 2 0 Actinobacteria/chloroflexi VLRF1 release factor DLH PF01738.18 ACL93975.1 - 6e-27 94.6 0.0 7.7e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 ACL93975.1 - 0.084 12.5 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 ACL93975.1 - 0.14 11.7 0.6 1.2 8.8 0.3 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ACL93975.1 - 0.19 12.3 10.1 0.07 13.7 1.5 2.3 1 1 1 2 2 2 0 Alpha/beta hydrolase family DLH PF01738.18 ACL93976.2 - 1e-36 126.5 0.3 1.2e-36 126.3 0.3 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 ACL93976.2 - 0.00018 22.2 6.7 0.009 16.6 1.7 2.6 1 1 2 3 3 3 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ACL93976.2 - 0.0037 16.6 0.4 0.59 9.4 0.1 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 BAAT_C PF08840.11 ACL93976.2 - 0.004 17.1 0.2 0.57 10.1 0.1 2.1 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 ACL93976.2 - 0.047 13.3 0.0 0.45 10.1 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold YchF-GTPase_C PF06071.13 ACL93977.1 - 2.5e-40 136.5 0.0 6e-40 135.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 ACL93977.1 - 8.1e-24 83.9 0.0 1.6e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ACL93977.1 - 7.1e-09 35.4 0.0 1.4e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 ACL93977.1 - 0.095 13.2 0.0 0.29 11.7 0.0 1.8 2 0 0 2 2 2 0 ABC transporter SRPRB PF09439.10 ACL93977.1 - 0.11 11.9 0.2 0.31 10.5 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Roc PF08477.13 ACL93977.1 - 0.2 11.9 0.0 0.33 11.2 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Pirin PF02678.16 ACL93979.1 - 1.8e-38 130.8 0.1 2.8e-38 130.2 0.1 1.3 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 ACL93979.1 - 5.2e-27 94.2 0.0 4.4e-26 91.2 0.0 2.2 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Pirin_C_2 PF17954.1 ACL93979.1 - 0.002 18.3 0.0 0.0043 17.2 0.0 1.6 1 0 0 1 1 1 1 Quercetinase C-terminal cupin domain Cupin_3 PF05899.12 ACL93979.1 - 0.0035 17.0 1.3 0.35 10.6 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_2 PF07883.11 ACL93979.1 - 0.01 15.5 2.2 0.63 9.8 0.4 2.3 2 0 0 2 2 2 0 Cupin domain NfeD PF01957.18 ACL93979.1 - 0.15 12.4 0.5 0.43 11.0 0.1 1.9 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding Meth_synt_2 PF01717.18 ACL93980.1 - 1.3e-152 507.8 0.0 1.4e-149 497.7 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 ACL93980.1 - 1.4e-120 402.6 0.0 5.6e-114 380.9 0.0 3.4 3 1 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain TPR_4 PF07721.14 ACL93981.1 - 3.9e-09 36.3 32.5 0.00061 20.2 1.2 5.4 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 ACL93981.1 - 2.5e-08 34.1 13.8 3.5e-05 24.0 0.7 3.6 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 ACL93981.1 - 4.6e-08 33.5 16.0 7.8e-05 23.1 4.5 3.9 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 ACL93981.1 - 2e-06 28.1 27.0 0.0011 19.6 0.8 5.2 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 ACL93981.1 - 5.6e-06 26.0 2.6 1.6 8.7 0.1 3.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 ACL93981.1 - 6.3e-06 26.0 1.2 0.22 11.8 0.0 4.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 ACL93981.1 - 9.3e-06 25.4 13.0 0.64 10.3 0.7 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 ACL93981.1 - 8.4e-05 22.3 19.6 0.012 15.4 1.5 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 ACL93981.1 - 0.00013 22.6 27.5 0.027 15.1 3.1 4.0 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 ACL93981.1 - 0.00033 20.5 9.5 0.025 14.6 0.4 4.2 5 0 0 5 5 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ACL93981.1 - 0.004 17.3 0.2 3.1 8.1 0.1 2.9 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 PLDc_N PF13396.6 ACL93981.1 - 0.0084 16.0 4.3 0.017 15.1 4.3 1.6 1 0 0 1 1 1 1 Phospholipase_D-nuclease N-terminal TPR_15 PF13429.6 ACL93981.1 - 0.0084 15.3 0.3 0.0084 15.3 0.3 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat Wzy_C_2 PF11846.8 ACL93981.1 - 0.021 14.7 12.4 0.28 11.1 0.8 3.1 2 2 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal TPR_6 PF13174.6 ACL93981.1 - 0.15 12.7 10.9 6.2 7.7 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 ACL93981.1 - 0.68 10.1 14.9 1.4 9.1 2.9 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Pept_tRNA_hydro PF01195.19 ACL93982.1 - 2.1e-48 164.5 0.0 2.6e-48 164.2 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Ribosomal_TL5_C PF14693.6 ACL93983.1 - 5e-27 94.1 1.2 8.7e-27 93.3 1.2 1.4 1 0 0 1 1 1 1 Ribosomal protein TL5, C-terminal domain Ribosomal_L25p PF01386.19 ACL93983.1 - 9.1e-26 90.2 0.0 1.7e-25 89.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal L25p family STI1 PF17830.1 ACL93984.1 - 0.0023 17.8 0.0 0.012 15.6 0.0 2.1 2 0 0 2 2 2 1 STI1 domain PRIMA1 PF16101.5 ACL93984.1 - 0.5 10.4 11.2 0.19 11.7 7.3 2.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Pribosyltran_N PF13793.6 ACL93985.1 - 2.2e-47 159.8 0.0 5.3e-47 158.6 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 ACL93985.1 - 1.2e-25 90.6 0.3 2.4e-25 89.6 0.3 1.6 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 ACL93985.1 - 9e-18 64.3 1.0 3.9e-17 62.2 0.4 2.1 2 0 0 2 2 2 1 Phosphoribosyl transferase domain CopG_antitoxin PF12441.8 ACL93986.1 - 4e-27 94.6 0.3 4.4e-27 94.4 0.3 1.0 1 0 0 1 1 1 1 CopG antitoxin of type II toxin-antitoxin system RHH_1 PF01402.21 ACL93986.1 - 0.00034 20.5 0.1 0.00054 19.8 0.1 1.4 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family Arc PF03869.14 ACL93986.1 - 0.012 15.5 0.2 0.019 14.8 0.2 1.3 1 0 0 1 1 1 0 Arc-like DNA binding domain BrnA_antitoxin PF14384.6 ACL93986.1 - 0.024 15.1 0.1 0.027 14.9 0.1 1.1 1 0 0 1 1 1 0 BrnA antitoxin of type II toxin-antitoxin system RHH_5 PF07878.11 ACL93986.1 - 0.06 13.2 0.1 0.1 12.5 0.1 1.4 1 1 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 BrnT_toxin PF04365.13 ACL93987.1 - 6.7e-16 58.4 0.0 7.9e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system Cu-oxidase_4 PF02578.15 ACL93988.1 - 4.6e-63 212.9 0.0 5.2e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 Multi-copper polyphenol oxidoreductase laccase Methyltransf_28 PF02636.17 ACL93989.1 - 6.8e-67 225.9 0.0 8.9e-67 225.5 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase LGT PF01790.18 ACL93990.1 - 1.2e-70 237.5 7.4 1.4e-70 237.3 7.4 1.0 1 0 0 1 1 1 1 Prolipoprotein diacylglyceryl transferase BMFP PF04380.13 ACL93991.1 - 2.7e-15 56.6 5.4 3.2e-15 56.4 5.4 1.0 1 0 0 1 1 1 1 Membrane fusogenic activity HALZ PF02183.18 ACL93991.1 - 0.00049 20.3 0.5 0.007 16.6 0.5 2.1 1 1 0 1 1 1 1 Homeobox associated leucine zipper RepA_C PF04796.12 ACL93991.1 - 0.002 18.1 0.0 0.0023 18.0 0.0 1.0 1 0 0 1 1 1 1 Plasmid encoded RepA protein Bap31_Bap29_C PF18035.1 ACL93991.1 - 0.0087 16.0 3.5 0.15 12.1 0.1 2.5 2 1 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain JIP_LZII PF16471.5 ACL93991.1 - 0.13 12.4 0.2 0.36 11.0 0.1 1.7 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II TipAS PF07739.13 ACL93991.1 - 0.2 12.2 3.8 0.33 11.5 3.8 1.5 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain YbjN PF10722.9 ACL93992.1 - 7.2e-32 110.1 0.3 9.3e-32 109.8 0.3 1.1 1 0 0 1 1 1 1 Putative bacterial sensory transduction regulator P5CR_dimer PF14748.6 ACL93993.1 - 3.9e-31 107.4 5.8 9.5e-31 106.1 5.8 1.7 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 ACL93993.1 - 5.2e-11 43.0 0.2 1.6e-10 41.4 0.2 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 ACL93993.1 - 0.0012 18.5 3.8 0.0016 18.1 0.7 2.4 2 1 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 ACL93993.1 - 0.086 12.8 0.1 0.086 12.8 0.1 2.2 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PDH PF02153.17 ACL93993.1 - 0.15 11.1 0.2 0.42 9.6 0.1 1.6 2 0 0 2 2 2 0 Prephenate dehydrogenase TetR_N PF00440.23 ACL93994.1 - 2.1e-05 24.2 0.5 2.1e-05 24.2 0.5 2.9 3 0 0 3 3 3 2 Bacterial regulatory proteins, tetR family Ribosomal_L10 PF00466.20 ACL93995.1 - 4.7e-22 78.0 0.1 7e-22 77.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Peptidase_S41 PF03572.18 ACL93995.1 - 0.034 13.7 0.0 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S41 DUF3130 PF11328.8 ACL93995.1 - 0.12 12.6 0.0 0.3 11.4 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3130 Ribosomal_L12 PF00542.19 ACL93996.1 - 2.6e-26 91.7 4.6 2.6e-26 91.7 4.6 2.1 2 1 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 ACL93996.1 - 9.2e-19 66.9 14.5 1.1e-18 66.6 12.2 2.1 2 0 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain DUF4147 PF13660.6 ACL93996.1 - 0.014 14.9 3.0 0.11 12.1 2.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4147) MCR_alpha PF02249.17 ACL93996.1 - 0.12 12.9 0.3 0.18 12.3 0.3 1.3 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain Ribosomal_60s PF00428.19 ACL93996.1 - 0.18 12.4 12.4 0.054 14.1 8.3 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein RDD PF06271.12 ACL93997.1 - 2.3e-22 79.7 2.9 4.2e-22 78.9 2.9 1.4 1 0 0 1 1 1 1 RDD family GYF_2 PF14237.6 ACL93997.1 - 0.029 14.2 0.6 0.06 13.2 0.1 1.8 2 0 0 2 2 2 0 GYF domain 2 Wzy_C PF04932.15 ACL93998.1 - 1.5e-07 31.2 29.6 0.0021 17.7 29.6 3.3 1 1 0 1 1 1 1 O-Antigen ligase O-antigen_lig PF13425.6 ACL93998.1 - 0.14 10.9 8.1 0.74 8.5 7.9 2.0 1 1 0 1 1 1 0 O-antigen ligase like membrane protein MMPL PF03176.15 ACL93998.1 - 1.5 7.7 11.4 0.045 12.7 3.7 2.1 2 0 0 2 2 2 0 MMPL family PSII_BNR PF14870.6 ACL93999.2 - 3.6e-06 26.5 0.1 1.2e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Photosynthesis system II assembly factor YCF48 Sortilin-Vps10 PF15902.5 ACL93999.2 - 3.2e-05 22.9 0.0 5.5e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, BNR PF02012.20 ACL93999.2 - 0.042 13.8 15.8 0.65 10.2 0.1 4.7 5 0 0 5 5 5 0 BNR/Asp-box repeat ApoO PF09769.9 ACL93999.2 - 0.15 12.1 0.1 0.31 11.0 0.1 1.5 1 0 0 1 1 1 0 Apolipoprotein O SecE PF00584.20 ACL94000.1 - 6.8 6.7 10.5 1.7 8.6 5.5 1.9 1 1 1 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex RNA_pol_Rpb2_6 PF00562.28 ACL94001.1 - 2.4e-165 550.3 0.0 6.2e-165 549.0 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 ACL94001.1 - 8.3e-34 116.9 0.0 2.6e-33 115.3 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 ACL94001.1 - 1.5e-32 111.6 0.0 2.8e-32 110.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 ACL94001.1 - 1e-26 93.2 0.0 2e-26 92.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 ACL94001.1 - 1.7e-24 86.5 0.0 1.6e-16 60.5 0.1 2.3 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_45 PF10385.9 ACL94001.1 - 2e-19 69.6 0.1 1.1e-18 67.2 0.2 2.3 2 0 0 2 2 2 1 RNA polymerase beta subunit external 1 domain LpxI_C PF06230.11 ACL94001.1 - 0.095 12.6 0.6 11 5.9 0.1 2.5 2 0 0 2 2 2 0 LpxI C-terminal domain RNA_pol_Rpb1_1 PF04997.12 ACL94002.1 - 1.8e-89 300.2 0.0 2.7e-89 299.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 ACL94002.1 - 2.1e-73 247.0 0.0 9.5e-73 244.9 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 ACL94002.1 - 1.6e-38 132.6 0.0 1.8e-35 122.6 0.0 2.6 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 ACL94002.1 - 2.1e-25 89.5 0.0 4.6e-25 88.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 ACL94002.1 - 2.4e-17 62.8 0.9 5.6e-17 61.7 0.9 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Biotin_lipoyl_2 PF13533.6 ACL94002.1 - 9.9e-07 28.5 0.8 0.2 11.5 0.0 4.2 4 0 0 4 4 4 2 Biotin-lipoyl like RnfC_N PF13375.6 ACL94002.1 - 0.0014 18.5 0.3 0.21 11.6 0.0 3.9 4 0 0 4 4 4 1 RnfC Barrel sandwich hybrid domain Peptidase_M23 PF01551.22 ACL94002.1 - 0.0014 18.8 0.1 8 6.7 0.0 3.8 3 0 0 3 3 3 1 Peptidase family M23 Apocytochr_F_C PF01333.19 ACL94002.1 - 0.0038 17.3 0.0 7.5 6.6 0.0 3.5 3 0 0 3 3 3 1 Apocytochrome F, C-terminal QRPTase_N PF02749.16 ACL94002.1 - 0.054 13.6 0.0 7.5 6.7 0.0 3.7 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, N-terminal domain ERp29 PF07749.12 ACL94002.1 - 0.062 14.2 0.2 0.062 14.2 0.2 2.7 2 0 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain MCPsignal PF00015.21 ACL94003.1 - 3.4e-48 163.7 22.7 5.2e-46 156.6 17.3 2.6 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 ACL94003.1 - 2.1e-11 44.0 0.9 2.7e-07 30.9 0.0 3.9 2 0 0 2 2 2 2 HAMP domain Collagen_mid PF15984.5 ACL94003.1 - 0.0087 15.8 2.7 0.0087 15.8 2.7 2.3 2 0 0 2 2 2 1 Bacterial collagen, middle region Laminin_II PF06009.12 ACL94003.1 - 0.062 13.3 8.3 1.7 8.7 1.1 2.9 2 1 0 2 2 2 0 Laminin Domain II DUF1664 PF07889.12 ACL94003.1 - 2.7 8.1 6.1 19 5.3 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 ACL94003.1 - 4.9 7.5 16.5 18 5.7 0.9 5.4 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF1593 PF07632.11 ACL94004.1 - 2.7e-96 322.0 0.0 3.6e-96 321.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) Coprogen_oxidas PF01218.18 ACL94005.1 - 5.2e-90 301.2 0.0 5.9e-90 301.0 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase HTH_31 PF13560.6 ACL94006.1 - 0.0019 18.5 0.4 0.0019 18.5 0.4 2.0 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_3 PF01381.22 ACL94006.1 - 0.0049 16.9 0.1 0.01 15.9 0.0 1.6 1 1 0 1 1 1 1 Helix-turn-helix ABC_tran_CTD PF16326.5 ACL94006.1 - 0.018 15.2 2.2 0.14 12.5 2.2 2.1 1 1 0 1 1 1 0 ABC transporter C-terminal domain HTH_26 PF13443.6 ACL94006.1 - 0.031 14.7 0.0 0.049 14.1 0.0 1.3 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain DUF1192 PF06698.11 ACL94006.1 - 0.69 10.0 5.2 0.27 11.3 1.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) PHB_acc_N PF07879.11 ACL94008.1 - 6e-30 103.1 1.1 8.8e-30 102.6 1.1 1.2 1 0 0 1 1 1 1 PHB/PHA accumulation regulator DNA-binding domain PHB_acc PF05233.13 ACL94008.1 - 2.8e-18 65.6 2.8 2.8e-18 65.6 2.8 2.7 3 0 0 3 3 3 1 PHB accumulation regulatory domain GAT PF03127.14 ACL94008.1 - 0.1 12.9 0.0 0.36 11.2 0.0 1.9 2 0 0 2 2 2 0 GAT domain TolA_bind_tri PF16331.5 ACL94008.1 - 0.11 12.6 1.9 1.2 9.3 0.2 2.3 2 0 0 2 2 2 0 TolA binding protein trimerisation PHA_synth_III_E PF09712.10 ACL94008.1 - 0.13 11.3 1.2 0.12 11.5 0.2 1.4 2 0 0 2 2 2 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) DUF2802 PF10975.8 ACL94008.1 - 0.14 12.3 1.8 9.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) Thiolase_N PF00108.23 ACL94009.1 - 1e-106 356.1 4.7 1.4e-106 355.7 4.7 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ACL94009.1 - 1.1e-52 176.8 4.2 1.1e-52 176.8 1.3 2.3 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ACL94009.1 - 0.00018 21.2 0.9 0.00018 21.2 0.9 3.5 3 2 2 5 5 5 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 ACL94009.1 - 0.00096 19.3 0.1 0.021 15.0 0.1 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 ACL94009.1 - 0.0069 16.2 1.3 0.43 10.5 0.1 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III adh_short PF00106.25 ACL94010.1 - 1.5e-61 207.3 3.0 1.8e-61 207.1 3.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ACL94010.1 - 1.7e-61 207.8 3.5 2.2e-61 207.4 3.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ACL94010.1 - 9e-19 68.1 0.3 1.3e-18 67.5 0.3 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ACL94010.1 - 5.5e-09 36.2 0.3 8e-09 35.6 0.3 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ACL94010.1 - 1.1e-06 28.4 0.1 3.2e-06 26.8 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 ACL94010.1 - 0.00068 20.2 0.6 0.0019 18.8 0.6 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.13 ACL94010.1 - 0.014 15.0 0.2 0.022 14.3 0.2 1.2 1 0 0 1 1 1 0 NmrA-like family DUF4908 PF16252.5 ACL94011.1 - 2.6e-115 383.6 2.4 3e-115 383.4 2.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4908) LacI PF00356.21 ACL94012.2 - 7.7e-07 28.8 0.1 9.6e-07 28.5 0.1 1.1 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family HTH_AsnC-type PF13404.6 ACL94012.2 - 0.0019 18.0 0.1 0.0025 17.6 0.1 1.1 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 ACL94012.2 - 0.002 17.6 0.0 0.0025 17.3 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 ACL94012.2 - 0.0024 17.8 0.0 0.0026 17.7 0.0 1.1 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_IclR PF09339.10 ACL94012.2 - 0.0033 17.2 0.0 0.0041 16.9 0.0 1.1 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 ACL94012.2 - 0.011 15.7 0.1 0.011 15.5 0.1 1.1 1 0 0 1 1 1 0 MarR family HTH_AraC PF00165.23 ACL94012.2 - 0.014 15.5 0.0 0.016 15.3 0.0 1.1 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_38 PF13936.6 ACL94012.2 - 0.016 15.0 0.1 0.019 14.7 0.1 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 ACL94012.2 - 0.016 15.0 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 Homeodomain-like domain TetR_N PF00440.23 ACL94012.2 - 0.038 13.8 0.0 0.051 13.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family MarR PF01047.22 ACL94012.2 - 0.042 13.8 0.0 0.05 13.5 0.0 1.1 1 0 0 1 1 1 0 MarR family HTH_Tnp_ISL3 PF13542.6 ACL94012.2 - 0.054 12.9 0.1 0.076 12.4 0.1 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.12 ACL94012.2 - 0.075 13.0 0.0 0.087 12.8 0.0 1.1 1 0 0 1 1 1 0 HTH domain MerR PF00376.23 ACL94012.2 - 0.078 12.8 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 MerR family regulatory protein HTH_3 PF01381.22 ACL94012.2 - 0.081 13.0 0.1 0.12 12.5 0.0 1.3 1 1 0 1 1 1 0 Helix-turn-helix Crp PF00325.20 ACL94012.2 - 0.13 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family HTH_5 PF01022.20 ACL94012.2 - 0.17 11.8 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_Tnp_1 PF01527.20 ACL94013.1 - 6.3e-22 77.7 0.3 7.5e-22 77.4 0.3 1.1 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 ACL94013.1 - 6.7e-05 22.9 0.1 0.00016 21.7 0.1 1.8 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 ACL94013.1 - 0.00034 20.3 0.1 0.00084 19.1 0.1 1.8 1 1 0 1 1 1 1 Homeodomain-like domain HTH_11 PF08279.12 ACL94013.1 - 0.0013 18.7 0.1 0.003 17.5 0.0 1.6 2 0 0 2 2 2 1 HTH domain HTH_29 PF13551.6 ACL94013.1 - 0.0045 17.0 0.1 0.013 15.5 0.1 2.0 1 1 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_1_2 PF13022.6 ACL94013.1 - 0.0058 16.8 0.1 0.013 15.7 0.1 1.6 1 1 0 1 1 1 1 Helix-turn-helix of insertion element transposase CENP-B_N PF04218.13 ACL94013.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_AsnC-type PF13404.6 ACL94013.1 - 0.02 14.7 0.1 0.09 12.6 0.0 2.1 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_psq PF05225.16 ACL94013.1 - 0.027 14.2 0.2 2.1 8.2 0.0 2.3 1 1 1 2 2 2 0 helix-turn-helix, Psq domain Terminase_5 PF06056.12 ACL94013.1 - 0.035 14.0 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_24 PF13412.6 ACL94013.1 - 0.047 13.3 2.3 0.19 11.3 0.0 2.7 3 1 1 4 4 4 0 Winged helix-turn-helix DNA-binding MerR PF00376.23 ACL94013.1 - 0.08 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 MerR family regulatory protein YdaS_antitoxin PF15943.5 ACL94013.1 - 0.1 12.5 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT MerR_1 PF13411.6 ACL94013.1 - 0.11 12.6 0.0 0.3 11.2 0.0 1.9 2 1 0 2 2 2 0 MerR HTH family regulatory protein rve_3 PF13683.6 ACL94014.1 - 4.2e-32 109.7 0.1 1e-31 108.5 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain rve PF00665.26 ACL94014.1 - 1.6e-23 83.2 0.0 2.8e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 ACL94014.1 - 1.6e-09 37.7 6.5 3.8e-09 36.5 6.5 1.6 1 0 0 1 1 1 1 HTH-like domain rve_2 PF13333.6 ACL94014.1 - 0.0013 18.8 0.0 0.0026 17.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain HTH_32 PF13565.6 ACL94014.1 - 4.6 7.9 15.2 2.9 8.6 2.3 3.6 2 1 1 4 4 4 0 Homeodomain-like domain Peripla_BP_3 PF13377.6 ACL94015.1 - 2.5e-35 122.3 2.1 4.2e-35 121.5 2.1 1.4 1 0 0 1 1 1 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 ACL94015.1 - 2.1e-17 63.4 0.1 2.5e-17 63.2 0.1 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 ACL94015.1 - 2.9e-14 53.3 1.0 4.3e-14 52.7 1.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain HTH_Crp_2 PF13545.6 ACL94016.1 - 0.0014 18.6 0.0 0.039 13.9 0.0 2.2 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain TrmB PF01978.19 ACL94016.1 - 0.0039 17.0 0.0 0.01 15.7 0.0 1.6 1 1 1 2 2 2 1 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 ACL94016.1 - 0.0057 16.5 1.0 0.46 10.4 0.2 2.2 1 1 1 2 2 2 1 MarR family Sigma70_r4 PF04545.16 ACL94016.1 - 0.012 15.1 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_IclR PF09339.10 ACL94016.1 - 0.015 15.1 0.1 0.033 14.0 0.1 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_DeoR PF08220.12 ACL94016.1 - 0.052 13.3 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_12 PF08461.10 ACL94016.1 - 0.058 13.3 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain HTH_20 PF12840.7 ACL94016.1 - 0.1 12.7 0.1 0.37 10.9 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain DUF977 PF06163.11 ACL94016.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) DUF2089 PF09862.9 ACL94016.1 - 0.19 11.8 0.0 0.26 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) Cupin_5 PF06172.11 ACL94017.1 - 2e-46 157.7 0.0 2.3e-46 157.5 0.0 1.0 1 0 0 1 1 1 1 Cupin superfamily (DUF985) HAGH_C PF16123.5 ACL94018.1 - 5.8e-19 68.4 0.0 8.4e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 ACL94018.1 - 7.2e-19 68.6 3.8 2.7e-18 66.7 3.8 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ACL94018.1 - 0.0032 17.0 0.1 0.0062 16.1 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Methyltransf_11 PF08241.12 ACL94019.1 - 1e-09 38.9 0.0 1.7e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ACL94019.1 - 4.1e-07 30.0 0.0 6.1e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ACL94019.1 - 0.003 18.2 0.0 0.0081 16.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ACL94019.1 - 0.0085 16.8 0.0 0.017 15.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ACL94019.1 - 0.24 11.2 0.0 0.35 10.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 ACL94019.1 - 0.32 10.1 0.0 0.58 9.2 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase P-II PF00543.22 ACL94020.1 - 4.7e-38 129.9 0.3 5.3e-38 129.7 0.3 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II DUF3240 PF11582.8 ACL94020.1 - 0.03 14.4 0.0 0.053 13.7 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3240) HisG_C PF08029.11 ACL94020.1 - 0.032 14.4 0.5 0.32 11.2 0.1 2.1 2 0 0 2 2 2 0 HisG, C-terminal domain DUF362 PF04015.12 ACL94020.1 - 0.038 14.2 0.1 0.49 10.6 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF362) Methyltrans_RNA PF04452.14 ACL94020.1 - 0.04 13.3 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 RNA methyltransferase PLDc_2 PF13091.6 ACL94021.1 - 4e-12 46.2 0.0 3.2e-09 36.8 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 ACL94021.1 - 1.3e-08 34.7 0.9 0.00012 22.1 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Exo_endo_phos PF03372.23 ACL94022.1 - 4.7e-18 65.6 0.0 7.7e-18 64.9 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MetW PF07021.12 ACL94023.1 - 4.7e-93 310.2 0.0 5.3e-93 310.0 0.0 1.0 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_11 PF08241.12 ACL94023.1 - 3.3e-11 43.7 0.4 3.7e-10 40.3 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ACL94023.1 - 3.4e-10 40.0 0.0 4.2e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ACL94023.1 - 1.4e-09 38.5 0.2 4.4e-09 36.9 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ACL94023.1 - 1e-08 35.1 0.0 1.6e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ACL94023.1 - 9.7e-08 32.7 0.1 2e-07 31.7 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ACL94023.1 - 0.00053 19.4 0.0 0.0007 19.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MdcG PF10620.9 ACL94023.1 - 0.015 15.1 0.3 0.076 12.8 0.2 1.9 2 0 0 2 2 2 0 Phosphoribosyl-dephospho-CoA transferase MdcG MTS PF05175.14 ACL94023.1 - 0.034 13.7 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 ACL94023.1 - 0.083 12.9 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 ACL94023.1 - 0.094 12.6 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 ACL94023.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 ACL94023.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Abhydrolase_1 PF00561.20 ACL94024.1 - 4.7e-32 111.6 0.2 6.3e-32 111.2 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ACL94024.1 - 0.00019 20.8 0.2 0.0011 18.3 0.2 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 zf-RING_6 PF14835.6 ACL94024.1 - 0.062 13.2 0.2 0.14 12.1 0.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein His_Phos_1 PF00300.22 ACL94025.1 - 3.1e-11 43.3 2.9 5.6e-10 39.2 0.9 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) ETF PF01012.21 ACL94025.1 - 0.016 15.1 1.1 4.1 7.2 0.2 2.1 1 1 1 2 2 2 0 Electron transfer flavoprotein domain TIR_2 PF13676.6 ACL94025.1 - 0.1 13.2 0.0 0.17 12.5 0.0 1.4 1 0 0 1 1 1 0 TIR domain adh_short PF00106.25 ACL94025.1 - 0.13 11.7 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase DUF952 PF06108.12 ACL94026.1 - 1.5e-29 101.8 0.0 1.7e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) DHO_dh PF01180.21 ACL94027.1 - 2.3e-78 263.4 0.0 2.6e-78 263.2 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 ACL94027.1 - 0.019 14.3 5.7 0.036 13.5 5.7 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase DNAPolymera_Pol PF11590.8 ACL94027.1 - 4 7.4 7.0 1.3 8.9 0.1 3.3 3 0 0 3 3 3 0 DNA polymerase catalytic subunit Pol SNARE_assoc PF09335.11 ACL94028.1 - 2.1e-20 73.4 13.8 2.1e-20 73.4 12.0 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein HATPase_c PF02518.26 ACL94029.1 - 1.7e-16 60.7 0.0 2.9e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ACL94029.1 - 2.9e-05 24.0 0.7 5.8e-05 23.0 0.1 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 ACL94029.1 - 0.0088 16.4 3.7 0.0096 16.3 1.6 2.3 2 0 0 2 2 2 1 HAMP domain HATPase_c_5 PF14501.6 ACL94029.1 - 0.035 14.0 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 GHKL domain HATPase_c_2 PF13581.6 ACL94029.1 - 0.15 12.0 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain G_glu_transpept PF01019.21 ACL94030.1 - 7.1e-155 516.7 0.1 8.1e-155 516.5 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase MR_MLE_C PF13378.6 ACL94031.1 - 9.4e-44 149.6 0.1 1.4e-43 149.0 0.1 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 ACL94031.1 - 3.6e-32 111.0 0.0 8.8e-32 109.8 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Glyco_hydro_92 PF07971.12 ACL94032.1 - 2.8e-157 524.4 0.1 3.4e-157 524.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 ACL94032.1 - 5.8e-58 196.6 1.6 8.3e-58 196.1 1.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Amidohydro_1 PF01979.20 ACL94033.1 - 1.1e-18 67.7 0.3 1.5e-18 67.3 0.3 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ACL94033.1 - 6.2e-06 26.0 0.8 7.9e-05 22.3 0.1 2.3 2 0 0 2 2 2 1 Amidohydrolase family SIS PF01380.22 ACL94034.1 - 7.5e-33 113.2 2.6 5.2e-17 61.9 1.1 2.2 2 0 0 2 2 2 2 SIS domain SIS_2 PF13580.6 ACL94034.1 - 0.02 14.9 2.4 0.31 11.1 0.1 3.2 2 2 2 4 4 4 0 SIS domain UTRA PF07702.13 ACL94035.1 - 8.3e-35 119.7 0.1 1.3e-34 119.1 0.1 1.3 1 0 0 1 1 1 1 UTRA domain GntR PF00392.21 ACL94035.1 - 7.9e-20 70.3 0.3 1.9e-19 69.0 0.3 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_DeoR PF08220.12 ACL94035.1 - 0.0034 17.1 0.1 0.0094 15.7 0.0 1.7 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain HTH_41 PF14502.6 ACL94035.1 - 0.036 13.7 0.0 0.084 12.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 ACL94035.1 - 0.063 13.3 0.2 0.42 10.6 0.0 2.5 3 0 0 3 3 3 0 Crp-like helix-turn-helix domain TrmB PF01978.19 ACL94035.1 - 0.099 12.5 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 ACL94035.1 - 0.1 13.0 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator MarR_2 PF12802.7 ACL94035.1 - 0.23 11.4 2.5 0.55 10.2 0.0 2.6 3 0 0 3 3 3 0 MarR family PEP-utilizers_C PF02896.18 ACL94036.1 - 5.9e-98 327.6 0.0 8.6e-98 327.1 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PTS_EIIA_1 PF00358.20 ACL94036.1 - 5.2e-42 142.6 0.0 1.3e-41 141.3 0.0 1.7 2 0 0 2 2 2 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 PTS-HPr PF00381.19 ACL94036.1 - 1.7e-23 82.7 0.1 4.7e-23 81.2 0.1 1.9 1 0 0 1 1 1 1 PTS HPr component phosphorylation site PEP-utilisers_N PF05524.13 ACL94036.1 - 1.4e-20 73.6 4.4 1.4e-20 73.6 4.4 3.2 3 0 0 3 3 3 1 PEP-utilising enzyme, N-terminal PEP-utilizers PF00391.23 ACL94036.1 - 9.3e-20 70.1 1.9 4.5e-19 67.9 1.0 2.6 2 0 0 2 2 2 1 PEP-utilising enzyme, mobile domain HpcH_HpaI PF03328.14 ACL94036.1 - 4e-06 26.1 0.1 4e-06 26.1 0.1 2.8 4 0 0 4 4 4 1 HpcH/HpaI aldolase/citrate lyase family Biotin_lipoyl_2 PF13533.6 ACL94036.1 - 0.00028 20.7 0.2 0.016 15.0 0.0 3.3 3 0 0 3 3 3 1 Biotin-lipoyl like Peptidase_M23 PF01551.22 ACL94036.1 - 0.059 13.6 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Peptidase family M23 PTS_EIIC PF02378.18 ACL94037.1 - 3.2e-70 236.7 26.8 3.2e-70 236.7 26.8 1.6 2 0 0 2 2 2 1 Phosphotransferase system, EIIC PTS_EIIB PF00367.20 ACL94037.1 - 5e-22 77.1 1.3 3.9e-11 42.2 0.2 2.5 2 0 0 2 2 2 2 phosphotransferase system, EIIB DUF4072 PF13284.6 ACL94037.1 - 0.091 13.2 7.1 2.6 8.6 2.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4072) TonB_dep_Rec PF00593.24 ACL94038.2 - 2.1e-34 120.2 22.9 2.1e-34 120.2 22.9 2.3 1 1 0 2 2 2 2 TonB dependent receptor Plug PF07715.15 ACL94038.2 - 4.1e-15 56.3 3.5 6.2e-15 55.7 1.4 2.2 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain NAGLU PF05089.12 ACL94039.1 - 6.3e-139 462.6 0.8 9e-139 462.1 0.8 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 ACL94039.1 - 7e-52 176.6 0.3 1.2e-51 175.8 0.3 1.4 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 ACL94039.1 - 3.7e-11 42.7 0.0 6.4e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain DUF1624 PF07786.12 ACL94040.1 - 9.2e-11 41.7 11.5 9.2e-11 41.7 11.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1624) DUF5009 PF16401.5 ACL94040.1 - 0.013 15.0 6.3 0.042 13.3 6.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5009) His_Phos_2 PF00328.22 ACL94041.1 - 5.4e-29 101.7 0.0 1.5e-28 100.3 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Glyco_hydro_115 PF15979.5 ACL94043.1 - 7.9e-131 436.5 0.0 1e-130 436.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 Glyco_hydro_67N PF03648.14 ACL94043.1 - 0.00052 20.3 0.0 0.0009 19.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Endonuclease_NS PF01223.23 ACL94044.1 - 8.3e-54 182.8 0.0 1.1e-53 182.4 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Trypsin_2 PF13365.6 ACL94044.1 - 7.9e-14 52.8 0.5 1.7e-13 51.7 0.5 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain AAA_16 PF13191.6 ACL94045.1 - 3.5e-13 50.3 5.2 3.5e-13 50.3 5.2 3.7 3 2 1 4 4 4 1 AAA ATPase domain NACHT PF05729.12 ACL94045.1 - 0.00012 22.0 0.2 0.00032 20.6 0.2 1.7 1 0 0 1 1 1 1 NACHT domain TPR_19 PF14559.6 ACL94045.1 - 0.00017 22.0 3.3 0.43 11.1 4.3 3.8 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_22 PF13401.6 ACL94045.1 - 0.00025 21.3 0.3 0.0027 18.0 0.0 2.8 1 1 2 3 3 3 1 AAA domain AAA_33 PF13671.6 ACL94045.1 - 0.013 15.7 0.0 0.037 14.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 ACL94045.1 - 0.07 12.1 0.1 0.26 10.2 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase_2 PF01637.18 ACL94045.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea APS_kinase PF01583.20 ACL94045.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_35 PF14516.6 ACL94045.1 - 0.19 10.5 0.0 0.34 9.7 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain DUF1353 PF07087.11 ACL94047.3 - 1.8e-28 98.1 0.0 2.5e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1353) LytTR PF04397.15 ACL94051.1 - 2.3e-17 63.0 0.0 3.3e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 LytTr DNA-binding domain DUF998 PF06197.13 ACL94051.1 - 0.65 9.6 42.1 0.071 12.7 24.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF998) Bax1-I PF01027.20 ACL94051.1 - 8.6 6.1 19.8 6.6 6.5 17.8 1.7 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Abhydrolase_1 PF00561.20 ACL94052.1 - 1e-21 77.8 0.0 4.7e-15 55.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ACL94052.1 - 5.8e-07 30.3 11.5 5.8e-07 30.3 11.5 3.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 ACL94052.1 - 3.4e-06 27.1 0.0 6.4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.8 ACL94052.1 - 5e-05 22.7 0.2 0.11 11.8 0.1 3.2 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 ACL94052.1 - 0.034 13.6 0.0 8.8 5.7 0.0 2.7 3 0 0 3 3 3 0 Prolyl oligopeptidase family DUF1598 PF07643.11 ACL94052.1 - 0.092 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1598) Trp_halogenase PF04820.14 ACL94055.1 - 1.7e-19 70.0 4.8 5.3e-11 42.0 2.1 2.2 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 ACL94055.1 - 9.3e-17 61.3 0.2 1.9e-16 60.3 0.2 1.5 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 ACL94055.1 - 1.1e-08 34.8 7.0 0.0017 17.8 5.4 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase DAO PF01266.24 ACL94055.1 - 7.1e-08 32.4 7.8 3.6e-05 23.5 0.9 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ACL94055.1 - 1.3e-06 27.9 0.7 0.00011 21.6 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ACL94055.1 - 2.7e-06 26.7 1.5 3e-05 23.3 1.5 2.2 1 1 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 ACL94055.1 - 4.4e-06 26.0 0.6 6.2e-06 25.5 0.6 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 ACL94055.1 - 3.5e-05 24.0 0.7 0.00015 22.0 0.7 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ACL94055.1 - 9.1e-05 21.9 1.9 0.00016 21.1 1.9 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ACL94055.1 - 0.00028 20.1 3.8 0.00028 20.1 3.8 2.6 3 0 0 3 3 3 1 FAD binding domain Pyr_redox PF00070.27 ACL94055.1 - 0.00095 19.7 0.1 0.0021 18.6 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ACL94055.1 - 0.001 17.9 0.7 0.0014 17.4 0.7 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 ACL94055.1 - 0.073 12.3 1.3 0.27 10.5 0.7 2.0 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.21 ACL94055.1 - 0.28 10.4 1.9 0.19 11.0 0.2 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain LodA_N PF17990.1 ACL94056.1 - 4.5e-58 196.7 0.0 6.3e-58 196.3 0.0 1.2 1 0 0 1 1 1 1 L-Lysine epsilon oxidase N-terminal LodA_C PF18417.1 ACL94056.1 - 3.1e-39 134.1 0.0 5.8e-39 133.2 0.0 1.4 1 0 0 1 1 1 1 L-lysine epsilon oxidase C-terminal domain Ferritin-like PF12902.7 ACL94057.1 - 8.6e-51 172.9 0.0 1e-50 172.7 0.0 1.1 1 0 0 1 1 1 1 Ferritin-like DUF3099 PF11298.8 ACL94059.1 - 0.23 11.6 0.4 1.1 9.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) FecR PF04773.13 ACL94060.1 - 4.2e-22 78.6 1.3 9.7e-22 77.4 0.2 1.9 2 0 0 2 2 2 1 FecR protein Cupin_3 PF05899.12 ACL94060.1 - 0.081 12.6 0.0 0.22 11.2 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF861) Glyco_hydro_65C PF03633.15 ACL94060.1 - 0.21 11.5 1.4 4.9 7.1 0.3 2.8 1 1 1 2 2 2 0 Glycosyl hydrolase family 65, C-terminal domain Sigma70_r4_2 PF08281.12 ACL94061.2 - 2.4e-10 39.9 2.8 3.7e-10 39.3 2.8 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 ACL94061.2 - 1.6e-07 30.8 2.9 3e-07 29.9 2.9 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 ACL94061.2 - 4.5e-05 23.1 0.4 9.7e-05 22.1 0.4 1.6 1 0 0 1 1 1 1 Sigma-70 region 2 TonB_dep_Rec PF00593.24 ACL94062.1 - 7.8e-28 98.6 8.5 7.8e-28 98.6 8.5 1.6 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 ACL94062.1 - 7.9e-09 36.0 0.2 4.1e-08 33.8 0.0 2.2 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 ACL94062.1 - 4.1e-06 26.0 0.0 5.8e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Outer membrane protein beta-barrel family STN PF07660.14 ACL94062.1 - 0.0017 18.1 0.0 0.0074 16.1 0.0 2.1 2 0 0 2 2 2 1 Secretin and TonB N terminus short domain TonB_dep_Rec PF00593.24 ACL94063.1 - 3.2e-42 146.0 23.6 3.2e-42 146.0 23.6 2.6 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 ACL94063.1 - 1.2e-16 61.2 1.4 4.4e-16 59.4 0.4 2.3 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain AAA_3 PF07726.11 ACL94066.1 - 1.7e-61 205.8 0.0 2.5e-61 205.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 ACL94066.1 - 9.7e-19 67.0 3.2 3.2e-18 65.4 3.2 1.9 1 0 0 1 1 1 1 AAA lid domain AAA_5 PF07728.14 ACL94066.1 - 1.3e-13 51.2 0.0 2.3e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 ACL94066.1 - 3.7e-07 29.7 0.4 2.1e-05 24.0 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 ACL94066.1 - 3.8e-07 29.9 0.0 1.6e-06 27.9 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain MCM PF00493.23 ACL94066.1 - 1.5e-05 24.3 0.0 4e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 MCM P-loop domain AAA PF00004.29 ACL94066.1 - 7e-05 23.3 0.0 0.00025 21.5 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 ACL94066.1 - 0.00014 21.6 0.0 0.00067 19.4 0.0 2.2 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ACL94066.1 - 0.00081 19.8 0.0 0.0017 18.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 ACL94066.1 - 0.0036 16.9 0.4 0.0085 15.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 ACL94066.1 - 0.01 15.2 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 KaiC TIP49 PF06068.13 ACL94066.1 - 0.067 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_7 PF12775.7 ACL94066.1 - 0.075 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 ACL94066.1 - 0.17 11.8 0.0 2.6 7.9 0.0 2.4 2 1 0 2 2 2 0 NACHT domain DUF58 PF01882.18 ACL94067.1 - 4.9e-20 71.6 0.0 2.1e-19 69.6 0.0 2.2 1 0 0 1 1 1 1 Protein of unknown function DUF58 VWA_CoxE PF05762.14 ACL94067.1 - 1.8e-06 27.5 2.9 4.6e-06 26.2 2.9 1.7 1 1 0 1 1 1 1 VWA domain containing CoxE-like protein VWA_2 PF13519.6 ACL94067.1 - 2.9e-06 27.9 0.0 6.2e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Ribosomal_S27e PF01667.17 ACL94067.1 - 0.0026 17.4 0.0 0.0048 16.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S27 SelB-wing_1 PF09105.10 ACL94067.1 - 0.38 10.7 5.2 5.6 7.0 0.0 3.7 4 0 0 4 4 4 0 Elongation factor SelB, winged helix SpoIIM PF01944.17 ACL94068.1 - 9.6e-31 106.9 11.5 1.5e-30 106.3 11.5 1.2 1 0 0 1 1 1 1 Stage II sporulation protein M RDD PF06271.12 ACL94069.1 - 1.9e-17 63.8 5.9 2.6e-17 63.3 5.9 1.2 1 0 0 1 1 1 1 RDD family GPDPase_memb PF10110.9 ACL94070.1 - 1.5e-05 23.9 3.2 1.5e-05 23.9 3.2 1.7 2 0 0 2 2 2 1 Membrane domain of glycerophosphoryl diester phosphodiesterase UPF0259 PF06790.11 ACL94070.1 - 0.0021 17.9 3.7 0.003 17.4 3.6 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0259) TonB_dep_Rec PF00593.24 ACL94072.1 - 1.1e-30 108.0 46.6 1.1e-30 108.0 46.6 3.1 1 1 2 3 3 3 1 TonB dependent receptor Plug PF07715.15 ACL94072.1 - 9.6e-09 35.8 1.9 2.6e-08 34.4 0.3 2.6 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain Pectate_lyase_3 PF12708.7 ACL94073.1 - 1.7e-16 60.7 1.1 1.2e-11 44.9 0.0 3.4 2 1 1 3 3 3 3 Pectate lyase superfamily protein Beta_helix PF13229.6 ACL94073.1 - 2.6e-10 40.4 0.0 2.4e-09 37.2 0.2 2.5 2 1 0 2 2 2 1 Right handed beta helix region Glyco_hydro_28 PF00295.17 ACL94073.1 - 1.6e-09 37.2 0.0 3.4e-06 26.4 0.0 2.2 1 1 0 2 2 2 2 Glycosyl hydrolases family 28 AGP PF06376.12 ACL94073.1 - 0.069 13.0 1.1 0.17 11.8 1.1 1.7 1 0 0 1 1 1 0 Arabinogalactan peptide Glyco_trans_4_4 PF13579.6 ACL94073.1 - 0.1 13.0 0.2 0.21 12.0 0.2 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain DUF4957 PF16318.5 ACL94073.1 - 0.14 12.1 0.6 2 8.4 0.2 2.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4957) LytB_WW PF18342.1 ACL94073.1 - 0.16 12.1 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 Endo-beta-N-acetylglucosaminidase LytB WW domain NosD PF05048.13 ACL94073.1 - 0.17 11.1 0.0 3.2 6.9 0.0 2.1 2 0 0 2 2 2 0 Periplasmic copper-binding protein (NosD) Peripla_BP_1 PF00532.21 ACL94074.1 - 3.8e-15 56.0 0.0 4.8e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 ACL94074.1 - 4.5e-14 53.1 0.9 8.1e-14 52.3 0.4 1.6 2 0 0 2 2 2 1 Periplasmic binding protein-like domain LacI PF00356.21 ACL94074.1 - 2.4e-10 40.0 0.3 1.3e-09 37.7 0.1 2.2 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 ACL94074.1 - 9.4e-09 35.2 0.0 1.2e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain HTH_AraC PF00165.23 ACL94074.1 - 0.077 13.1 0.0 18 5.6 0.0 2.6 3 0 0 3 3 3 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_10 PF04967.12 ACL94074.1 - 0.095 12.5 0.1 0.66 9.8 0.1 2.2 2 0 0 2 2 2 0 HTH DNA binding domain Glyco_hydro_92 PF07971.12 ACL94075.1 - 1.4e-109 367.1 0.0 1.7e-109 366.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 ACL94075.1 - 7.6e-45 153.7 0.0 1.4e-44 152.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain F5_F8_type_C PF00754.25 ACL94075.1 - 0.0013 18.9 0.0 0.0031 17.6 0.0 1.6 1 0 0 1 1 1 1 F5/8 type C domain Beta-lactamase PF00144.24 ACL94076.2 - 2e-49 168.6 1.9 2.1e-49 168.6 0.9 1.5 2 0 0 2 2 2 1 Beta-lactamase TPR_2 PF07719.17 ACL94076.2 - 0.0048 16.9 0.1 0.014 15.5 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 ACL94076.2 - 0.0092 16.7 3.7 0.029 15.2 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 ACL94076.2 - 0.16 12.2 0.0 0.36 11.2 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Asparaginase_2 PF01112.18 ACL94077.1 - 2.8e-81 272.9 10.0 9.4e-81 271.2 10.0 1.7 1 1 0 1 1 1 1 Asparaginase DUF1727 PF08353.10 ACL94077.1 - 0.095 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1727) Peptidase_S51 PF03575.17 ACL94078.3 - 5.6e-09 35.9 0.0 1.1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S51 TraD PF06412.11 ACL94078.3 - 0.055 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Conjugal transfer protein TraD DcuC PF03606.15 ACL94079.2 - 3.5e-152 507.1 20.8 3.9e-152 506.9 20.8 1.0 1 0 0 1 1 1 1 C4-dicarboxylate anaerobic carrier ABG_transport PF03806.13 ACL94079.2 - 5.9e-07 28.1 5.4 5.9e-07 28.1 5.4 2.9 2 1 1 3 3 3 1 AbgT putative transporter family DUF4079 PF13301.6 ACL94079.2 - 0.11 12.6 4.3 0.17 12.0 0.7 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) TonB_dep_Rec PF00593.24 ACL94080.1 - 8.5e-48 164.4 21.4 8.5e-48 164.4 21.4 2.5 1 1 0 2 2 2 1 TonB dependent receptor Plug PF07715.15 ACL94080.1 - 2.1e-19 70.1 1.6 4.7e-19 69.0 1.6 1.6 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain DUF3695 PF12494.8 ACL94080.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3695) HTH_24 PF13412.6 ACL94081.2 - 1.3e-18 66.3 0.2 6.1e-18 64.1 0.1 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding AsnC_trans_reg PF01037.21 ACL94081.2 - 1.4e-18 66.6 0.0 2.1e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_AsnC-type PF13404.6 ACL94081.2 - 9.4e-18 63.8 3.9 2.6e-17 62.4 2.3 2.2 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_IclR PF09339.10 ACL94081.2 - 0.0016 18.2 0.7 0.0033 17.2 0.7 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain MarR_2 PF12802.7 ACL94081.2 - 0.0083 16.0 1.2 0.015 15.1 0.6 1.7 2 0 0 2 2 2 1 MarR family MarR PF01047.22 ACL94081.2 - 0.011 15.6 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_20 PF12840.7 ACL94081.2 - 0.021 14.9 0.5 0.044 13.8 0.5 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_28 PF13518.6 ACL94081.2 - 0.045 13.9 0.2 0.074 13.2 0.2 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain AstA PF04958.12 ACL94082.1 - 6.3e-112 373.5 0.0 7.3e-112 373.2 0.0 1.0 1 0 0 1 1 1 1 Arginine N-succinyltransferase beta subunit Aldedh PF00171.22 ACL94083.1 - 6.9e-118 394.1 0.0 8.3e-118 393.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AstB PF04996.12 ACL94084.1 - 1.2e-173 577.9 0.2 1.3e-173 577.8 0.2 1.0 1 0 0 1 1 1 1 Succinylarginine dihydrolase Aminotran_3 PF00202.21 ACL94085.1 - 5.6e-114 381.0 0.0 7.8e-114 380.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III DegT_DnrJ_EryC1 PF01041.17 ACL94085.1 - 0.078 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family HATPase_c PF02518.26 ACL94088.1 - 1.6e-28 99.4 0.2 3.3e-28 98.4 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 ACL94088.1 - 3.3e-17 62.6 0.0 7.7e-08 32.5 0.0 2.4 2 0 0 2 2 2 2 PAS fold HisKA PF00512.25 ACL94088.1 - 4.7e-17 61.8 1.3 2e-16 59.8 0.0 2.8 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 ACL94088.1 - 2e-15 57.0 1.7 1.2e-10 41.5 0.3 2.7 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 ACL94088.1 - 5.8e-11 42.4 0.0 0.00036 20.5 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 ACL94088.1 - 7e-10 39.1 0.0 1.8e-05 24.9 0.0 2.5 2 0 0 2 2 2 2 PAS domain HATPase_c_3 PF13589.6 ACL94088.1 - 7.7e-05 22.5 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ACL94088.1 - 0.016 15.3 0.0 0.068 13.3 0.0 2.1 1 0 0 1 1 1 0 Response regulator receiver domain Trp_ring PF18669.1 ACL94088.1 - 0.18 12.0 0.1 0.5 10.6 0.1 1.7 1 0 0 1 1 1 0 Trimeric autotransporter adhesin Trp ring domain Pentapeptide PF00805.22 ACL94089.1 - 4.2e-58 192.5 29.4 3.7e-15 55.2 3.0 8.5 6 2 2 9 9 9 8 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 ACL94089.1 - 5.4e-24 84.1 0.0 1.9e-06 27.9 0.0 5.9 3 2 2 5 5 5 5 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.6 ACL94089.1 - 2e-21 75.9 0.0 6.2e-07 29.5 0.0 5.5 2 2 3 5 5 5 5 Pentapeptide repeats (9 copies) Response_reg PF00072.24 ACL94090.1 - 5.6e-27 94.1 0.0 6.3e-27 94.0 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain MCPsignal PF00015.21 ACL94091.1 - 1.7e-42 145.1 19.4 1.7e-42 145.1 19.4 3.5 4 0 0 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 ACL94091.1 - 1.2e-07 32.0 13.6 5.4e-06 26.7 0.0 6.2 6 0 0 6 6 6 2 HAMP domain Laminin_II PF06009.12 ACL94091.1 - 0.0039 17.2 15.6 0.85 9.6 5.4 4.5 2 1 2 4 4 4 2 Laminin Domain II Golgin_A5 PF09787.9 ACL94091.1 - 0.022 14.2 3.8 0.53 9.7 0.0 2.8 3 0 0 3 3 3 0 Golgin subfamily A member 5 DUF3782 PF12644.7 ACL94091.1 - 0.057 13.6 0.1 3 8.1 0.0 3.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) Baculo_PEP_C PF04513.12 ACL94091.1 - 0.28 11.2 14.6 0.69 10.0 0.0 4.6 2 1 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus RPW8 PF05659.11 ACL94091.1 - 0.46 10.2 2.6 5 6.8 0.1 3.6 4 0 0 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 BLOC1_2 PF10046.9 ACL94091.1 - 0.68 10.3 7.6 9.2 6.6 0.0 4.8 5 2 1 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AIP3 PF03915.13 ACL94091.1 - 1.4 7.9 7.3 0.46 9.5 4.2 2.0 2 0 0 2 2 2 0 Actin interacting protein 3 CheZ PF04344.13 ACL94092.1 - 0.011 15.6 0.0 0.014 15.3 0.0 1.1 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ Response_reg PF00072.24 ACL94093.1 - 2.7e-28 98.4 0.1 3.1e-28 98.2 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain MCPsignal PF00015.21 ACL94094.1 - 1.3e-29 103.2 26.8 1.3e-29 103.2 26.8 3.1 2 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 ACL94094.1 - 0.00031 21.1 0.2 0.00031 21.1 0.2 5.6 7 1 1 8 8 8 1 HAMP domain HAP1_N PF04849.13 ACL94094.1 - 0.011 15.0 6.1 0.18 11.0 0.1 2.9 2 1 1 3 3 3 0 HAP1 N-terminal conserved region PI3K_P85_iSH2 PF16454.5 ACL94094.1 - 0.042 13.5 1.2 0.13 11.8 1.2 1.9 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF148 PF02520.17 ACL94094.1 - 0.11 12.7 18.3 0.21 11.7 4.1 4.3 3 2 2 5 5 5 0 Domain of unknown function DUF148 APG6_N PF17675.1 ACL94094.1 - 0.11 13.0 0.3 0.11 13.0 0.3 2.9 3 1 0 3 3 3 0 Apg6 coiled-coil region Vps4_C PF09336.10 ACL94094.1 - 0.16 12.0 0.1 5.2 7.2 0.0 2.9 2 1 1 3 3 3 0 Vps4 C terminal oligomerisation domain TSNAXIP1_N PF15739.5 ACL94094.1 - 0.5 10.8 2.0 9.2 6.7 0.0 3.1 3 0 0 3 3 3 0 Translin-associated factor X-interacting N-terminus DUF948 PF06103.11 ACL94094.1 - 1.3 9.3 39.8 0.048 13.9 3.6 6.5 4 2 2 6 6 6 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 ACL94094.1 - 2.1 8.5 13.4 2.8 8.1 0.1 3.8 3 2 1 4 4 4 0 Fibrinogen alpha/beta chain family TMPIT PF07851.13 ACL94094.1 - 3.9 6.6 8.1 7.5 5.7 0.9 2.4 2 0 0 2 2 2 0 TMPIT-like protein V_ATPase_I PF01496.19 ACL94094.1 - 6.2 4.6 7.8 10 3.9 7.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-C4H2 PF10146.9 ACL94094.1 - 9.4 6.5 9.2 1.6 9.0 1.9 2.5 1 1 0 2 2 2 0 Zinc finger-containing protein CheW PF01584.19 ACL94095.1 - 3.9e-29 101.0 7.9 1.1e-24 86.6 1.0 2.5 2 0 0 2 2 2 2 CheW-like domain Hpt PF01627.23 ACL94095.1 - 1.8e-16 60.2 0.4 7.1e-16 58.2 0.4 2.1 1 0 0 1 1 1 1 Hpt domain HATPase_c PF02518.26 ACL94095.1 - 1.9e-13 50.9 0.1 3.5e-13 50.0 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase H-kinase_dim PF02895.14 ACL94095.1 - 1e-12 48.2 0.2 3.1e-12 46.7 0.2 1.9 1 0 0 1 1 1 1 Signal transducing histidine kinase, homodimeric domain CT47 PF15623.6 ACL94095.1 - 0.037 13.9 2.6 0.076 12.8 2.6 1.5 1 0 0 1 1 1 0 Cancer/testis gene family 47 CheW PF01584.19 ACL94096.1 - 2.1e-25 89.0 0.1 2.5e-25 88.7 0.1 1.0 1 0 0 1 1 1 1 CheW-like domain Response_reg PF00072.24 ACL94097.1 - 5.9e-32 110.2 0.0 6.6e-32 110.0 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain CheB_methylest PF01339.17 ACL94098.1 - 6.8e-57 191.9 0.0 1.9e-56 190.4 0.0 1.8 2 0 0 2 2 2 1 CheB methylesterase Response_reg PF00072.24 ACL94098.1 - 1.2e-22 80.2 0.1 2.5e-22 79.1 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain CheR PF01739.18 ACL94099.1 - 2.4e-54 183.8 0.0 3.1e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain CheR_N PF03705.15 ACL94099.1 - 3.4e-08 33.1 0.0 5.7e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain Methyltransf_25 PF13649.6 ACL94099.1 - 8.4e-06 26.4 0.0 0.0015 19.2 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ACL94099.1 - 0.00017 22.2 0.0 0.0019 18.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ACL94099.1 - 0.00022 21.9 0.0 0.0046 17.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ACL94099.1 - 0.0088 15.9 0.0 0.85 9.4 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain NAS PF03059.16 ACL94099.1 - 0.075 12.4 0.0 0.49 9.7 0.0 1.9 1 1 1 2 2 2 0 Nicotianamine synthase protein CHASE2 PF05226.11 ACL94100.2 - 5.6e-18 65.6 0.0 7.6e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 CHASE2 domain BiPBP_C PF06832.12 ACL94101.1 - 0.0069 16.4 0.1 0.12 12.5 0.1 2.7 2 1 0 2 2 2 1 Penicillin-Binding Protein C-terminus Family Big_3_5 PF16640.5 ACL94101.1 - 3.5 7.9 8.9 0.82 9.9 1.0 3.4 3 1 1 4 4 4 0 Bacterial Ig-like domain (group 3) CHAT PF12770.7 ACL94102.1 - 6.2e-47 160.4 0.6 1.5e-46 159.2 0.6 1.7 1 0 0 1 1 1 1 CHAT domain Type_III_YscG PF09477.10 ACL94102.1 - 0.0034 17.4 0.1 0.044 13.8 0.2 2.8 2 0 0 2 2 2 1 Bacterial type II secretion system chaperone protein (type_III_yscG) U62_UL91 PF17442.2 ACL94102.1 - 0.068 13.2 0.4 12 5.9 0.1 2.9 3 0 0 3 3 3 0 Functional domain of U62 and UL91 proteins TPR_10 PF13374.6 ACL94102.1 - 0.085 12.8 7.8 8.9 6.3 2.9 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Haemagg_act PF05860.13 ACL94103.1 - 1.5e-20 73.3 3.0 1.5e-20 73.3 3.0 2.6 2 0 0 2 2 2 1 haemagglutination activity domain POTRA_2 PF08479.11 ACL94104.1 - 5e-19 67.9 0.0 2.3e-18 65.8 0.0 2.2 3 0 0 3 3 3 1 POTRA domain, ShlB-type ShlB PF03865.13 ACL94104.1 - 5.8e-15 55.5 0.0 1.1e-14 54.6 0.0 1.5 1 1 0 1 1 1 1 Haemolysin secretion/activation protein ShlB/FhaC/HecB Bac_surface_Ag PF01103.23 ACL94104.1 - 6.2e-05 22.6 0.1 0.00012 21.7 0.1 1.7 1 1 0 1 1 1 1 Surface antigen Alginate_exp PF13372.6 ACL94109.2 - 4.3e-12 45.5 3.5 2.6e-11 42.9 1.8 2.1 1 1 0 2 2 2 2 Alginate export Pax7 PF12360.8 ACL94109.2 - 0.041 14.1 1.5 0.047 13.9 0.1 1.8 2 0 0 2 2 2 0 Paired box protein 7 NMT1_2 PF13379.6 ACL94110.1 - 6.2e-95 317.7 1.9 8.3e-95 317.3 1.9 1.2 1 0 0 1 1 1 1 NMT1-like family BPD_transp_1 PF00528.22 ACL94111.1 - 4.7e-26 91.6 14.0 4.7e-26 91.6 14.0 1.7 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 ACL94112.1 - 4.3e-31 108.2 0.0 6.2e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 ACL94112.1 - 6.7e-05 22.9 0.1 0.00011 22.1 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 ACL94112.1 - 0.00024 21.0 0.7 0.075 12.8 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ACL94112.1 - 0.00044 19.9 0.2 0.00084 19.0 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 ACL94112.1 - 0.0046 17.3 0.1 0.0062 16.9 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.9 ACL94112.1 - 0.015 14.1 1.5 0.35 9.6 0.1 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA PF00004.29 ACL94112.1 - 0.017 15.5 0.1 0.2 12.1 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 ACL94112.1 - 0.022 14.9 0.0 0.065 13.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ACL94112.1 - 0.022 14.8 0.1 0.047 13.8 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 ACL94112.1 - 0.037 13.6 0.0 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 ACL94112.1 - 0.042 14.1 0.5 0.11 12.8 0.5 1.9 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ACL94112.1 - 0.097 13.2 0.1 0.14 12.6 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 ACL94112.1 - 0.14 12.1 0.2 2.9 7.9 0.0 2.4 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 ACL94112.1 - 0.16 11.1 0.1 0.3 10.2 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain SMC_N PF02463.19 ACL94112.1 - 0.19 11.2 0.3 1.2 8.5 0.1 1.9 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ANTAR PF03861.14 ACL94113.1 - 1.9e-19 69.3 1.1 5.7e-19 67.7 1.1 1.9 1 0 0 1 1 1 1 ANTAR domain Response_reg PF00072.24 ACL94113.1 - 0.05 13.8 0.0 0.091 12.9 0.0 1.5 1 0 0 1 1 1 0 Response regulator receiver domain FleQ PF06490.11 ACL94113.1 - 0.19 12.1 0.0 0.34 11.3 0.0 1.4 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ NMT1_2 PF13379.6 ACL94114.1 - 6.5e-66 222.6 0.2 8.9e-66 222.2 0.2 1.1 1 0 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 ACL94114.1 - 0.00018 21.5 0.0 0.0012 18.8 0.0 1.9 2 0 0 2 2 2 1 NMT1/THI5 like MFS_1 PF07690.16 ACL94115.2 - 2.8e-47 161.4 40.8 2.8e-47 161.4 40.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 ACL94115.2 - 0.00015 20.4 35.8 0.0079 14.8 4.7 3.9 1 1 3 4 4 4 4 MFS/sugar transport protein PC_rep PF01851.22 ACL94115.2 - 8.8 7.0 7.9 0.63 10.6 1.0 2.7 2 0 0 2 2 2 0 Proteasome/cyclosome repeat Pyr_redox_2 PF07992.14 ACL94116.1 - 6.6e-58 196.3 1.4 1e-57 195.6 1.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 ACL94116.1 - 2.1e-29 101.6 3.6 2.6e-13 50.1 0.0 2.7 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain NIR_SIR PF01077.22 ACL94116.1 - 4.8e-26 91.2 0.0 8.9e-26 90.3 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Rubredoxin_C PF18267.1 ACL94116.1 - 3.2e-18 65.4 0.0 7.3e-18 64.3 0.0 1.6 1 0 0 1 1 1 1 Rubredoxin NAD+ reductase C-terminal domain Pyr_redox PF00070.27 ACL94116.1 - 5e-17 62.2 4.4 1.4e-15 57.6 0.7 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR_ferr PF03460.17 ACL94116.1 - 6.9e-15 54.7 0.0 2.3e-14 53.0 0.0 1.9 2 0 0 2 2 2 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox_3 PF13738.6 ACL94116.1 - 1.9e-05 24.0 0.0 3.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ACL94116.1 - 4.9e-05 23.1 7.7 0.093 12.3 2.2 4.0 4 0 0 4 4 4 2 FAD dependent oxidoreductase GIDA PF01134.22 ACL94116.1 - 0.0003 20.0 3.6 0.011 14.8 1.0 3.4 3 1 1 4 4 4 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 ACL94116.1 - 0.00091 18.4 6.3 0.16 11.1 2.7 3.4 2 1 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.21 ACL94116.1 - 0.0015 17.9 0.3 0.08 12.2 0.3 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 ACL94116.1 - 0.0025 16.8 0.1 0.0025 16.8 0.1 2.0 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.6 ACL94116.1 - 0.0045 17.2 1.7 0.4 10.9 1.4 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ACL94116.1 - 0.036 12.8 0.8 26 3.3 0.0 3.6 4 0 0 4 4 4 0 HI0933-like protein NAD_binding_9 PF13454.6 ACL94116.1 - 0.11 12.5 7.3 21 5.1 0.0 4.6 5 0 0 5 5 5 0 FAD-NAD(P)-binding Rieske PF00355.26 ACL94117.1 - 1.3e-15 57.1 0.0 1.6e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 ACL94117.1 - 2.9e-10 40.0 0.0 3.2e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Molybdopterin PF00384.22 ACL94118.1 - 6.9e-72 242.8 0.0 8.8e-72 242.4 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 ACL94118.1 - 2.3e-32 111.3 0.0 4.6e-32 110.3 0.0 1.5 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 ACL94118.1 - 1e-15 57.4 0.7 2.3e-15 56.3 0.7 1.6 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Fe4S4 domain Fer2_BFD PF04324.15 ACL94118.1 - 6.9e-12 45.5 2.8 1.7e-11 44.2 2.8 1.8 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain SelB-wing_2 PF09106.11 ACL94118.1 - 0.43 10.8 1.6 3.8 7.8 0.1 2.7 2 0 0 2 2 2 0 Elongation factor SelB, winged helix TP_methylase PF00590.20 ACL94119.1 - 2.4e-43 148.6 5.2 2.9e-43 148.3 5.2 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DAHP_snth_FXD PF18152.1 ACL94119.1 - 0.0064 16.3 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 DAHP synthase ferredoxin-like domain N6_Mtase PF02384.16 ACL94121.2 - 3.7e-58 197.3 0.0 5e-58 196.8 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase HsdM_N PF12161.8 ACL94121.2 - 1.8e-20 74.0 0.0 6.9e-20 72.1 0.0 2.0 2 0 0 2 2 2 1 HsdM N-terminal domain MTS PF05175.14 ACL94121.2 - 0.01 15.4 0.0 0.078 12.5 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Methylase_S PF01420.19 ACL94122.1 - 3e-24 86.1 0.0 3e-11 43.8 0.0 2.1 2 0 0 2 2 2 2 Type I restriction modification DNA specificity domain Mrr_cat PF04471.12 ACL94123.1 - 1.6e-17 63.6 0.0 3.1e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease DNA_pol3_gamma3 PF12169.8 ACL94123.1 - 0.0048 16.8 0.0 0.68 9.8 0.0 2.5 2 0 0 2 2 2 2 DNA polymerase III subunits gamma and tau domain III SWI2_SNF2 PF18766.1 ACL94124.1 - 5.9e-21 75.2 0.8 6.7e-20 71.7 0.8 2.1 1 1 0 1 1 1 1 SWI2/SNF2 ATPase HSDR_N PF04313.14 ACL94124.1 - 4.1e-15 56.2 0.0 8.7e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) ResIII PF04851.15 ACL94124.1 - 2.3e-12 47.2 0.2 4.3e-12 46.4 0.2 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ACL94124.1 - 2.9e-05 23.9 0.5 6.2e-05 22.8 0.5 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase rve PF00665.26 ACL94125.1 - 9e-33 113.0 0.0 1.4e-32 112.3 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain HTH_32 PF13565.6 ACL94125.1 - 5.5e-16 58.9 0.7 1.9e-15 57.2 0.1 2.3 2 0 0 2 2 2 1 Homeodomain-like domain rve_3 PF13683.6 ACL94125.1 - 3.6e-15 55.5 0.5 6.9e-15 54.6 0.5 1.5 1 0 0 1 1 1 1 Integrase core domain HTH_28 PF13518.6 ACL94125.1 - 3e-10 40.1 0.8 1.4e-09 37.9 0.0 2.4 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_29 PF13551.6 ACL94125.1 - 3.1e-07 30.3 0.0 2.5e-06 27.4 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 ACL94125.1 - 5.1e-07 29.3 7.0 1.2e-06 28.2 0.0 3.7 4 0 0 4 4 4 1 Homeodomain-like domain HTH_Tnp_1 PF01527.20 ACL94125.1 - 4e-06 27.1 0.0 2e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 Transposase LZ_Tnp_IS481 PF13011.6 ACL94125.1 - 5.2e-06 26.9 0.0 1.2e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 leucine-zipper of insertion element IS481 DDE_Tnp_IS240 PF13610.6 ACL94125.1 - 0.00016 21.9 0.0 0.001 19.3 0.0 2.3 2 1 0 2 2 2 1 DDE domain CENP-B_N PF04218.13 ACL94125.1 - 0.008 15.8 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HU-CCDC81_bac_1 PF18174.1 ACL94125.1 - 0.0088 15.9 0.0 0.051 13.5 0.0 2.1 2 0 0 2 2 2 1 CCDC81-like prokaryotic HU domain 1 HTH_Tnp_1 PF01527.20 ACL94126.3 - 4.6e-10 39.7 0.2 1e-09 38.6 0.2 1.7 1 1 0 1 1 1 1 Transposase HTH_28 PF13518.6 ACL94126.3 - 0.0029 17.7 0.1 0.0052 16.9 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Cas_Cas1 PF01867.16 ACL94126.3 - 0.099 11.8 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 CRISPR associated protein Cas1 COMP PF11598.8 ACL94126.3 - 0.28 11.7 2.2 0.32 11.5 0.8 1.9 2 1 0 2 2 2 0 Cartilage oligomeric matrix protein DUF4028 PF13220.6 ACL94127.2 - 0.093 12.5 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4028) Zn_Tnp_IS1595 PF12760.7 ACL94128.1 - 0.0045 16.9 3.4 0.02 14.8 3.4 2.0 1 1 0 1 1 1 1 Transposase zinc-ribbon domain SDF PF00375.18 ACL94129.2 - 8.3e-101 337.8 31.8 9.3e-101 337.7 31.8 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family HWE_HK PF07536.14 ACL94130.1 - 9.7e-28 96.7 0.1 2.1e-27 95.6 0.1 1.6 1 0 0 1 1 1 1 HWE histidine kinase GAF_2 PF13185.6 ACL94130.1 - 8.7e-10 39.0 0.2 2.6e-09 37.5 0.0 1.9 3 0 0 3 3 3 1 GAF domain HisKA_2 PF07568.12 ACL94130.1 - 3.1e-08 33.6 0.0 7.6e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase GAF PF01590.26 ACL94130.1 - 1.4e-05 25.8 0.1 3.2e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 GAF domain HATPase_c_2 PF13581.6 ACL94130.1 - 2.9e-05 24.0 0.0 7.8e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain GAF_3 PF13492.6 ACL94130.1 - 0.02 15.2 0.0 0.052 13.9 0.0 1.7 1 0 0 1 1 1 0 GAF domain Response_reg PF00072.24 ACL94131.1 - 1.2e-09 38.3 0.0 1.7e-09 37.8 0.0 1.2 1 1 0 1 1 1 1 Response regulator receiver domain DUF563 PF04577.14 ACL94132.1 - 2.6e-23 83.3 0.0 3.7e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF563 PF04577.14 ACL94133.1 - 6.5e-27 95.0 0.0 8.3e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Glyco_tran_WbsX PF14307.6 ACL94134.1 - 2.7e-125 418.4 0.0 3.4e-125 418.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase WbsX RgpF PF05045.12 ACL94134.1 - 9e-29 100.6 0.0 1.1e-28 100.3 0.0 1.1 1 0 0 1 1 1 1 Rhamnan synthesis protein F Glyco_hydro_99 PF16317.5 ACL94134.1 - 0.0015 17.7 0.0 0.014 14.5 0.0 2.2 3 0 0 3 3 3 1 Glycosyl hydrolase family 99 ABC_tran PF00005.27 ACL94135.1 - 6.6e-19 68.8 0.0 1.5e-18 67.7 0.0 1.6 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ACL94135.1 - 9.6e-05 21.9 0.4 0.13 11.6 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ACL94135.1 - 0.00037 20.4 0.3 0.00064 19.6 0.1 1.5 2 0 0 2 2 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ACL94135.1 - 0.0009 18.9 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 ACL94135.1 - 0.0015 18.3 0.1 0.002 17.9 0.1 1.1 1 0 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 ACL94135.1 - 0.0017 18.4 0.0 0.12 12.4 0.0 2.2 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE XdhC_C PF13478.6 ACL94135.1 - 0.0033 17.9 0.3 0.006 17.1 0.3 1.4 1 0 0 1 1 1 1 XdhC Rossmann domain AAA_23 PF13476.6 ACL94135.1 - 0.0047 17.4 0.1 0.0066 17.0 0.1 1.2 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 ACL94135.1 - 0.012 15.5 0.2 1.4 8.8 0.1 2.2 2 0 0 2 2 2 0 NTPase AAA PF00004.29 ACL94135.1 - 0.014 15.8 0.2 0.09 13.2 0.2 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 ACL94135.1 - 0.016 14.4 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit NACHT PF05729.12 ACL94135.1 - 0.018 14.9 0.1 0.034 14.1 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 ACL94135.1 - 0.021 14.5 0.9 0.06 13.1 0.9 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ACL94135.1 - 0.027 14.8 0.0 0.036 14.4 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 ACL94135.1 - 0.032 14.1 0.2 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase DUF3584 PF12128.8 ACL94135.1 - 0.056 11.0 0.1 0.076 10.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) cobW PF02492.19 ACL94135.1 - 0.058 13.0 1.9 0.47 10.0 0.1 2.6 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 ACL94135.1 - 0.068 12.8 0.1 0.15 11.6 0.0 1.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 ACL94135.1 - 0.072 13.2 0.1 0.19 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ACL94135.1 - 0.083 12.5 0.1 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 ACL94135.1 - 0.087 13.4 0.5 0.33 11.5 0.5 1.9 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 ACL94135.1 - 0.11 12.2 0.2 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 ACL94135.1 - 0.12 11.6 0.1 0.32 10.3 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.22 ACL94135.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Mg_chelatase PF01078.21 ACL94135.1 - 0.13 11.7 0.1 0.24 10.8 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PduV-EutP PF10662.9 ACL94135.1 - 0.13 12.0 0.1 0.36 10.6 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 ACL94135.1 - 0.15 11.8 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC2_membrane PF01061.24 ACL94136.1 - 3e-14 52.9 22.3 4.8e-14 52.3 22.3 1.3 1 0 0 1 1 1 1 ABC-2 type transporter Chitin_synth_2 PF03142.15 ACL94136.1 - 0.58 8.7 5.4 0.83 8.2 5.4 1.2 1 0 0 1 1 1 0 Chitin synthase DUF2306 PF10067.9 ACL94137.1 - 9.9e-06 25.8 5.5 9.9e-06 25.8 5.5 2.4 1 1 1 2 2 2 1 Predicted membrane protein (DUF2306) ABC2_membrane PF01061.24 ACL94137.1 - 0.25 10.8 7.6 35 3.7 7.0 3.2 1 1 0 1 1 1 0 ABC-2 type transporter Acyl_transf_3 PF01757.22 ACL94137.1 - 3.3 6.7 19.0 6.3 5.8 7.5 2.0 1 1 1 2 2 2 0 Acyltransferase family Arabinose_bd PF12625.7 ACL94138.1 - 2.7e-48 164.5 6.0 4.8e-48 163.7 6.0 1.4 1 0 0 1 1 1 1 Arabinose-binding domain of AraC transcription regulator, N-term HTH_18 PF12833.7 ACL94138.1 - 4.9e-17 62.0 2.6 4.9e-17 62.0 2.6 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 ACL94138.1 - 7.1e-11 41.9 0.0 7.4e-05 22.7 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_28 PF13518.6 ACL94138.1 - 0.0063 16.6 0.1 0.11 12.6 0.0 2.6 1 1 0 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.15 ACL94138.1 - 0.0099 15.9 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase ANT PF03374.14 ACL94138.1 - 0.012 15.9 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain HTH_8 PF02954.19 ACL94138.1 - 0.015 15.0 0.1 0.032 14.0 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family HTH_23 PF13384.6 ACL94138.1 - 0.016 15.0 0.1 0.4 10.5 0.0 2.5 1 1 2 3 3 3 0 Homeodomain-like domain SurA_N PF09312.11 ACL94138.1 - 0.14 12.2 0.1 0.36 10.9 0.0 1.6 2 0 0 2 2 2 0 SurA N-terminal domain DUF4880 PF16220.5 ACL94138.1 - 0.18 11.7 0.3 0.18 11.7 0.3 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4880) HTH_22 PF13309.6 ACL94138.1 - 0.19 11.8 0.0 0.48 10.5 0.0 1.6 1 0 0 1 1 1 0 HTH domain HI0933_like PF03486.14 ACL94139.1 - 6e-110 367.8 0.0 6.8e-110 367.6 0.0 1.0 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 ACL94139.1 - 2.4e-09 36.8 0.0 6.6e-09 35.3 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 ACL94139.1 - 4.8e-07 29.7 1.5 0.0026 17.4 0.3 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ACL94139.1 - 2.2e-06 27.8 0.1 8e-06 26.0 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 ACL94139.1 - 5.6e-06 26.0 0.1 5.6e-06 26.0 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ACL94139.1 - 1.2e-05 24.7 0.2 3e-05 23.4 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ACL94139.1 - 1.3e-05 24.6 0.5 2.1e-05 24.0 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 ACL94139.1 - 0.00013 21.3 0.1 0.00041 19.7 0.1 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 ACL94139.1 - 0.00017 22.1 0.0 0.00067 20.2 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ACL94139.1 - 0.00033 19.9 1.4 0.00058 19.0 0.4 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 ACL94139.1 - 0.0029 16.7 0.1 0.0057 15.8 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 ACL94139.1 - 0.0041 16.4 0.1 0.0064 15.8 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ACL94139.1 - 0.0056 16.0 0.1 0.0089 15.3 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 ACL94139.1 - 0.018 13.9 0.2 0.026 13.4 0.2 1.1 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 ACL94139.1 - 0.093 12.7 0.2 0.19 11.7 0.2 1.8 1 1 0 1 1 1 0 FAD-NAD(P)-binding PIN PF01850.21 ACL94140.1 - 6.7e-18 65.3 0.1 7.4e-18 65.2 0.1 1.0 1 0 0 1 1 1 1 PIN domain acVLRF1 PF18859.1 ACL94140.1 - 0.042 14.1 0.5 0.059 13.7 0.1 1.5 2 0 0 2 2 2 0 Actinobacteria/chloroflexi VLRF1 release factor P22_Cro PF14549.6 ACL94140.1 - 0.056 13.3 0.4 0.1 12.5 0.4 1.5 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro HRDC PF00570.23 ACL94140.1 - 0.064 13.2 0.6 0.1 12.6 0.6 1.3 1 0 0 1 1 1 0 HRDC domain PSK_trans_fac PF07704.11 ACL94141.1 - 4.6e-15 56.1 2.8 5e-15 56.0 2.8 1.0 1 0 0 1 1 1 1 Rv0623-like transcription factor DUF349 PF03993.12 ACL94141.1 - 0.021 15.1 1.3 0.021 15.1 1.3 1.5 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) Ribosomal_L1 PF00687.21 ACL94142.1 - 5.5e-55 186.3 0.0 7e-55 185.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_L11_N PF03946.14 ACL94143.1 - 1.5e-31 108.0 0.3 2.4e-31 107.3 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 ACL94143.1 - 2.6e-22 79.1 0.9 4.5e-22 78.3 0.9 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain NMT1 PF09084.11 ACL94143.1 - 0.03 14.3 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 NMT1/THI5 like DEDD_Tnp_IS110 PF01548.17 ACL94144.1 - 4.3e-20 72.1 0.0 8e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Transposase Transposase_20 PF02371.16 ACL94144.1 - 8e-18 64.5 0.2 1.9e-17 63.3 0.2 1.7 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family AP_endonuc_2 PF01261.24 ACL94144.1 - 0.098 12.1 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel DSBA PF01323.20 ACL94145.1 - 2.8e-32 112.1 0.0 3.2e-32 111.9 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 ACL94145.1 - 0.16 12.1 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin His_kinase PF06580.13 ACL94145.1 - 0.21 11.9 0.0 0.37 11.2 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase adh_short PF00106.25 ACL94146.1 - 8.9e-32 110.1 0.9 1.1e-31 109.8 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ACL94146.1 - 3.1e-30 105.5 1.5 3.8e-30 105.2 1.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ACL94146.1 - 6.5e-07 29.4 2.5 4.3e-06 26.8 2.3 1.9 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 ACL94146.1 - 0.025 14.5 0.1 0.039 13.8 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 ACL94146.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family HxlR PF01638.17 ACL94147.2 - 7e-21 73.9 0.0 9.5e-21 73.5 0.0 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix MarR_2 PF12802.7 ACL94147.2 - 0.0013 18.6 0.5 0.0036 17.1 0.1 1.9 3 0 0 3 3 3 1 MarR family MarR PF01047.22 ACL94147.2 - 0.009 15.9 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 ACL94147.2 - 0.019 15.0 0.1 0.087 12.9 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain GntR PF00392.21 ACL94147.2 - 0.026 14.2 0.2 0.052 13.2 0.2 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 ACL94147.2 - 0.071 12.7 0.1 0.17 11.5 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_12 PF08461.10 ACL94147.2 - 0.091 12.7 0.1 0.55 10.2 0.1 2.0 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain DPRP PF04244.13 ACL94148.1 - 1.5e-76 257.1 0.0 2.3e-76 256.6 0.0 1.3 1 0 0 1 1 1 1 Deoxyribodipyrimidine photo-lyase-related protein Cupin_7 PF12973.7 ACL94149.1 - 1.2e-10 41.2 0.0 1.7e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 ChrR Cupin-like domain Cupin_2 PF07883.11 ACL94149.1 - 6.7e-06 25.7 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Cupin domain zf-HC2 PF13490.6 ACL94149.1 - 0.0078 16.4 0.1 0.021 15.0 0.1 1.8 1 0 0 1 1 1 1 Putative zinc-finger Auxin_BP PF02041.16 ACL94149.1 - 0.084 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Auxin binding protein Sigma70_r2 PF04542.14 ACL94150.1 - 6.7e-18 64.2 0.3 1.1e-17 63.5 0.3 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 ACL94150.1 - 3.9e-14 51.9 0.0 6.6e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 ACL94150.1 - 4.9e-13 48.5 0.0 8.4e-13 47.8 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_24 PF13412.6 ACL94150.1 - 0.019 14.5 0.0 0.038 13.6 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma70_ECF PF07638.11 ACL94150.1 - 0.1 12.5 0.0 0.21 11.4 0.0 1.6 2 0 0 2 2 2 0 ECF sigma factor SUA5 PF03481.13 ACL94150.1 - 0.12 13.0 0.0 0.17 12.5 0.0 1.4 1 1 0 1 1 1 0 Putative GTP-binding controlling metal-binding Ub-Mut7C PF14451.6 ACL94150.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Mut7-C ubiquitin DUF2073 PF09846.9 ACL94150.1 - 0.2 11.6 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2073) Peptidase_S41 PF03572.18 ACL94151.1 - 1.5e-20 73.4 0.0 2.1e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S41 MFS_1 PF07690.16 ACL94153.1 - 1.4 7.8 46.2 0.0057 15.6 17.8 2.5 1 1 1 2 2 2 0 Major Facilitator Superfamily PAS_3 PF08447.12 ACL94154.1 - 5.5e-48 161.2 0.0 2.2e-18 66.3 0.1 3.5 3 0 0 3 3 3 3 PAS fold HATPase_c PF02518.26 ACL94154.1 - 1.5e-28 99.5 0.0 3e-28 98.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 ACL94154.1 - 4.2e-23 81.5 0.0 6.2e-08 32.6 0.0 3.6 3 0 0 3 3 3 3 PAS fold Response_reg PF00072.24 ACL94154.1 - 3.5e-18 65.8 0.2 8e-18 64.7 0.2 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ACL94154.1 - 2e-17 63.0 0.3 2e-16 59.8 0.0 2.9 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 ACL94154.1 - 3.7e-17 62.5 0.0 1.1e-06 28.9 0.0 3.5 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.10 ACL94154.1 - 1.5e-16 60.6 5.8 1.3e-06 28.6 0.3 3.7 3 0 0 3 3 3 3 PAS fold PAS_11 PF14598.6 ACL94154.1 - 4.1e-08 33.3 0.0 0.0016 18.6 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_8 PF13188.7 ACL94154.1 - 0.00026 21.0 0.0 1.4 9.0 0.0 3.8 3 0 0 3 3 3 1 PAS domain HATPase_c_2 PF13581.6 ACL94154.1 - 0.027 14.4 0.6 0.085 12.8 0.0 2.2 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 ACL94154.1 - 0.033 14.0 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase OmpH PF03938.14 ACL94154.1 - 0.89 9.9 5.0 0.22 11.8 0.2 2.4 3 0 0 3 3 2 0 Outer membrane protein (OmpH-like) CarD_CdnL_TRCF PF02559.16 ACL94155.2 - 6.1e-20 71.7 0.0 8.9e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 CarD-like/TRCF domain DUF3470 PF11953.8 ACL94156.1 - 4.8e-17 61.6 0.3 7.2e-17 61.1 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3470) Fer4 PF00037.27 ACL94156.1 - 3.8e-11 42.3 21.7 2.4e-08 33.5 7.2 3.1 3 0 0 3 3 3 3 4Fe-4S binding domain Fer4_10 PF13237.6 ACL94156.1 - 1.6e-08 34.5 8.8 4.2e-05 23.6 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 ACL94156.1 - 5.5e-08 33.3 26.8 3.1e-05 24.5 15.8 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.7 ACL94156.1 - 4.2e-07 29.7 14.2 0.0017 18.3 2.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 ACL94156.1 - 4.7e-07 30.6 7.8 6.3e-05 23.8 0.4 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_6 PF12837.7 ACL94156.1 - 7.6e-06 25.8 20.3 0.00025 21.0 5.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 ACL94156.1 - 4.8e-05 23.4 16.9 0.0028 17.8 2.7 2.1 1 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 ACL94156.1 - 5.2e-05 23.3 13.3 0.00015 21.8 13.4 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 ACL94156.1 - 6.8e-05 23.2 7.4 0.0025 18.2 0.0 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 ACL94156.1 - 7.9e-05 22.9 16.1 0.0013 19.0 2.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 ACL94156.1 - 0.0016 19.0 11.2 0.018 15.6 1.8 2.2 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_11 PF13247.6 ACL94156.1 - 0.24 11.5 8.3 0.49 10.5 8.4 1.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 ACL94156.1 - 0.66 11.0 21.1 3.1 9.0 4.7 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain ETF_QO PF05187.13 ACL94156.1 - 1.4 9.0 7.5 0.44 10.7 3.1 2.1 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_13 PF13370.6 ACL94156.1 - 8 7.1 18.2 3.1 8.4 6.6 3.0 2 1 1 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I EAL PF00563.20 ACL94157.1 - 1.4e-69 234.2 0.0 2.1e-69 233.7 0.0 1.3 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 ACL94157.1 - 1.3e-46 158.3 0.0 3.8e-46 156.8 0.0 1.8 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_3 PF08447.12 ACL94157.1 - 2.5e-08 34.1 0.0 1.6e-07 31.5 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 ACL94157.1 - 1.4e-05 25.3 0.6 0.00076 19.7 0.2 2.7 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 ACL94157.1 - 0.023 14.9 0.0 0.2 11.9 0.0 2.4 2 0 0 2 2 2 0 PAS domain MltA PF03562.17 ACL94157.1 - 0.11 12.2 0.0 13 5.5 0.0 2.3 2 0 0 2 2 2 0 MltA specific insert domain DUF1421 PF07223.11 ACL94157.1 - 0.12 12.3 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain (DUF1421) S4 PF01479.25 ACL94158.1 - 1.7e-08 34.0 0.7 2.1e-05 24.2 0.1 2.2 2 0 0 2 2 2 2 S4 domain DUF3253 PF11625.8 ACL94158.1 - 0.044 14.0 0.1 0.1 12.8 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3253) Helicase_C PF00271.31 ACL94159.1 - 7.1e-10 39.2 0.1 1.9e-09 37.9 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Amidohydro_3 PF07969.11 ACL94160.1 - 6.6e-96 322.6 13.1 7.8e-96 322.4 13.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 ACL94160.1 - 1.3e-11 44.4 0.7 2.5e-07 30.4 0.4 3.0 2 1 0 2 2 2 2 Amidohydrolase family DNA_binding_1 PF01035.20 ACL94161.1 - 1.3e-29 102.1 0.0 1.8e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain DUF3617 PF12276.8 ACL94163.2 - 0.0032 17.8 0.1 0.0072 16.7 0.0 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF3617) Ribosomal_L28 PF00830.19 ACL94164.1 - 4.2e-20 71.7 0.0 6.7e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal L28 family TonB_dep_Rec PF00593.24 ACL94165.2 - 6.4e-21 75.8 4.6 7.1e-21 75.6 0.8 2.0 1 1 1 2 2 2 1 TonB dependent receptor CSD PF00313.22 ACL94166.1 - 1.5e-21 76.0 0.0 1.5e-21 76.0 0.0 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 ACL94166.1 - 0.0097 15.6 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease B OB domain Phytase-like PF13449.6 ACL94172.1 - 2.8e-23 83.3 0.0 4.9e-17 62.8 0.0 2.1 2 0 0 2 2 2 2 Esterase-like activity of phytase SdiA-regulated PF06977.11 ACL94172.1 - 0.23 10.6 0.0 0.69 9.1 0.0 1.7 2 0 0 2 2 2 0 SdiA-regulated CobT_C PF11775.8 ACL94173.1 - 1.4e-110 368.1 0.1 2e-110 367.6 0.1 1.2 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT VWA domain CobT PF06213.12 ACL94173.1 - 1.4e-88 296.9 21.2 2.2e-88 296.3 21.2 1.3 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT VWA_CoxE PF05762.14 ACL94173.1 - 0.01 15.2 0.5 0.073 12.5 0.2 2.2 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein VWA PF00092.28 ACL94173.1 - 0.035 14.4 0.0 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 von Willebrand factor type A domain VWA_2 PF13519.6 ACL94173.1 - 0.056 14.1 0.1 2.6 8.7 0.0 2.8 3 0 0 3 3 3 0 von Willebrand factor type A domain SDA1 PF05285.12 ACL94173.1 - 1.9 7.9 16.4 2.7 7.3 16.4 1.2 1 0 0 1 1 1 0 SDA1 PTPRCAP PF15713.5 ACL94173.1 - 5.6 7.3 19.5 6.2 7.1 18.2 1.8 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 ACL94173.1 - 9.8 4.3 11.9 14 3.8 11.9 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1328 PF07043.13 ACL94174.1 - 1.2e-12 47.9 22.2 1.6e-12 47.4 22.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1328) DUF3089 PF11288.8 ACL94175.1 - 1.6e-57 194.3 0.0 2.1e-57 193.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) Abhydrolase_6 PF12697.7 ACL94175.1 - 0.001 19.7 3.4 0.0011 19.7 2.6 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ACL94175.1 - 0.15 11.3 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF726 PF05277.12 ACL94175.1 - 0.21 10.5 1.6 0.25 10.2 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF726) IMCp PF12314.8 ACL94176.1 - 0.002 18.4 26.8 0.002 18.4 26.8 3.3 1 1 1 2 2 2 1 Inner membrane complex protein ArsC PF03960.15 ACL94176.1 - 0.17 11.9 0.2 0.17 11.9 0.2 1.9 3 0 0 3 3 3 0 ArsC family CPBP PF02517.16 ACL94183.1 - 3.9e-14 52.8 9.5 3.9e-14 52.8 9.5 1.9 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease HlyD_3 PF13437.6 ACL94184.1 - 1.8e-14 54.3 7.1 1.2e-12 48.4 0.9 2.9 3 0 0 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 ACL94184.1 - 6.5e-09 35.5 7.7 1.7e-05 24.5 0.2 3.8 3 0 0 3 3 3 2 Biotin-lipoyl like HlyD_D23 PF16576.5 ACL94184.1 - 3.1e-07 29.8 7.6 0.00031 20.0 7.6 2.3 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl PF00364.22 ACL94184.1 - 1.1e-06 28.4 1.5 0.0044 16.8 0.1 2.5 2 0 0 2 2 2 2 Biotin-requiring enzyme RnfC_N PF13375.6 ACL94184.1 - 0.0095 15.9 0.4 0.3 11.1 0.0 2.5 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain Peptidase_M23 PF01551.22 ACL94184.1 - 0.013 15.7 1.2 6.3 7.1 0.0 2.5 2 0 0 2 2 2 0 Peptidase family M23 MutL_C PF08676.11 ACL94184.1 - 0.017 14.9 1.0 0.03 14.1 1.0 1.3 1 0 0 1 1 1 0 MutL C terminal dimerisation domain sCache_2 PF17200.4 ACL94184.1 - 0.055 13.3 0.1 0.086 12.7 0.1 1.3 1 0 0 1 1 1 0 Single Cache domain 2 Atg14 PF10186.9 ACL94184.1 - 0.66 9.0 4.3 0.89 8.6 4.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HlyD PF00529.20 ACL94184.1 - 8.6 6.3 27.7 31 4.5 27.6 2.2 1 1 0 1 1 1 0 HlyD membrane-fusion protein of T1SS Peptidase_C39 PF03412.15 ACL94185.1 - 2.3e-33 114.8 0.0 3.5e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase C39 family ABC_tran PF00005.27 ACL94185.1 - 2.7e-32 112.1 0.0 5.2e-32 111.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 ACL94185.1 - 2.8e-30 105.9 13.1 3.8e-30 105.5 13.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 ACL94185.1 - 9.9e-06 25.1 0.0 7.5e-05 22.3 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Peptidase_C70 PF12385.8 ACL94185.1 - 0.0031 17.5 0.0 0.01 15.8 0.0 1.9 2 1 0 2 2 2 1 Papain-like cysteine protease AvrRpt2 AAA_22 PF13401.6 ACL94185.1 - 0.014 15.7 0.6 0.12 12.6 0.6 2.3 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ACL94185.1 - 0.019 14.7 0.0 0.05 13.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 ACL94185.1 - 0.03 14.1 0.1 0.35 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ACL94185.1 - 0.039 14.3 0.6 0.16 12.3 0.6 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 ACL94185.1 - 0.14 12.4 0.1 0.31 11.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain Peptidase_C39_2 PF13529.6 ACL94185.1 - 0.22 12.0 0.0 0.51 10.9 0.0 1.6 1 0 0 1 1 1 0 Peptidase_C39 like family NACHT PF05729.12 ACL94185.1 - 0.3 11.0 2.3 4.1 7.3 0.4 2.4 2 0 0 2 2 2 0 NACHT domain SbcCD_C PF13558.6 ACL94185.1 - 3.6 7.9 7.2 0.73 10.1 0.2 3.3 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit Cpn60_TCP1 PF00118.24 ACL94186.1 - 3.3e-100 336.1 20.7 5.4e-100 335.4 20.7 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family HalX PF08663.10 ACL94186.1 - 2.3 8.6 5.0 0.38 11.1 0.6 2.0 2 0 0 2 2 2 0 HalX domain Cpn10 PF00166.21 ACL94187.1 - 3.9e-38 129.4 0.6 4.2e-38 129.3 0.6 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Peptidase_S24 PF00717.23 ACL94187.1 - 0.17 11.9 1.7 4.4 7.3 0.3 2.6 1 1 1 2 2 2 0 Peptidase S24-like Glyoxalase PF00903.25 ACL94188.1 - 0.00027 21.1 0.4 0.35 11.1 0.0 2.0 1 1 1 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF4345 PF14248.6 ACL94189.1 - 5.2e-09 36.0 10.0 6.6e-09 35.7 10.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4345) DUF2390 PF09523.10 ACL94189.1 - 0.081 13.3 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) DUF3169 PF11368.8 ACL94189.1 - 4.6 6.7 5.5 4.7 6.7 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Shadoo PF14999.6 ACL94189.1 - 7.8 6.6 11.1 2.9 8.0 5.8 2.0 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective DNA_binding_1 PF01035.20 ACL94190.1 - 1.7e-32 111.3 0.1 2.6e-32 110.8 0.1 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_1N PF02870.15 ACL94190.1 - 5.5e-06 27.1 0.0 9e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain Acyl-CoA_dh_1 PF00441.24 ACL94191.1 - 1.1e-35 123.1 2.8 1.9e-35 122.3 2.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ACL94191.1 - 3.3e-19 68.9 0.0 5.9e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ACL94191.1 - 7.8e-17 62.0 0.0 1.6e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ACL94191.1 - 5.2e-11 43.0 1.1 8.8e-11 42.2 1.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CoA_binding_2 PF13380.6 ACL94191.1 - 0.08 13.4 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 CoA binding domain Acetyltransf_3 PF13302.7 ACL94192.2 - 6.3e-11 43.1 0.0 8.7e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Toast_rack_N PF17115.5 ACL94192.2 - 0.082 13.2 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of toast_rack, DUF2154 TipAS PF07739.13 ACL94195.1 - 7.1e-29 100.7 0.7 7.1e-29 100.7 0.7 1.8 2 0 0 2 2 2 1 TipAS antibiotic-recognition domain MerR_1 PF13411.6 ACL94195.1 - 1.4e-13 50.7 0.0 2.3e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 ACL94195.1 - 9.9e-13 47.6 0.1 2.1e-12 46.6 0.1 1.6 1 0 0 1 1 1 1 MerR family regulatory protein Mg_chelatase_C PF13335.6 ACL94195.1 - 0.0033 18.0 0.9 0.0072 16.9 0.2 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI C-terminal HTH_17 PF12728.7 ACL94195.1 - 0.014 15.6 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain MerR-DNA-bind PF09278.11 ACL94195.1 - 0.043 14.4 5.0 0.1 13.1 5.0 1.7 1 0 0 1 1 1 0 MerR, DNA binding YqjK PF13997.6 ACL94195.1 - 0.064 13.5 1.1 0.064 13.5 1.1 2.0 2 0 0 2 2 2 0 YqjK-like protein Hemerythrin PF01814.23 ACL94195.1 - 0.24 12.0 6.6 0.46 11.1 6.6 1.5 1 1 0 1 1 1 0 Hemerythrin HHE cation binding domain Fe_dep_repr_C PF02742.15 ACL94195.1 - 4.2 7.5 5.3 9.9 6.3 0.0 3.1 4 0 0 4 4 4 0 Iron dependent repressor, metal binding and dimerisation domain MutL_C PF08676.11 ACL94196.1 - 3e-51 173.1 0.0 5e-51 172.3 0.0 1.4 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 ACL94196.1 - 3.1e-36 123.6 0.0 5.7e-36 122.8 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 ACL94196.1 - 4e-10 39.7 0.0 7.1e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 ACL94196.1 - 5.1e-06 27.0 0.0 1e-05 26.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TraB PF01963.17 ACL94197.1 - 8.4e-33 114.4 0.0 1e-32 114.1 0.0 1.1 1 0 0 1 1 1 1 TraB family TraB PF01963.17 ACL94198.1 - 2.8e-30 106.1 0.0 3.3e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 TraB family TraB PF01963.17 ACL94199.1 - 1.5e-24 87.3 0.0 1.8e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 TraB family DUF3035 PF11233.8 ACL94200.1 - 8.9e-34 116.8 2.0 2.2e-33 115.5 2.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3035) Peptidase_A8 PF01252.18 ACL94201.2 - 4.5e-36 124.2 3.3 5.3e-36 124.0 3.3 1.0 1 0 0 1 1 1 1 Signal peptidase (SPase) II DUF2593 PF10767.9 ACL94201.2 - 0.031 14.3 0.2 0.05 13.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2593) CorA PF01544.18 ACL94201.2 - 0.22 10.8 0.5 0.34 10.2 0.5 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein tRNA-synt_1 PF00133.22 ACL94202.1 - 1.6e-168 561.7 0.0 2.1e-168 561.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 ACL94202.1 - 3.3e-19 69.4 0.0 5.4e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 ACL94202.1 - 1.5e-17 63.5 0.0 1.3e-09 37.3 0.0 3.4 3 1 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 ACL94202.1 - 1.9e-06 27.5 0.0 0.021 14.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 ACL94202.1 - 0.00015 20.8 0.0 0.00074 18.5 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (K) Trypsin_2 PF13365.6 ACL94203.1 - 1.6e-34 119.9 1.0 3.3e-34 118.9 1.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 ACL94203.1 - 2.3e-12 47.2 0.0 7.5e-12 45.5 0.0 1.7 1 1 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 ACL94203.1 - 4.4e-11 42.9 0.0 9.8e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 ACL94203.1 - 6.3e-09 35.6 0.0 1.8e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 ACL94203.1 - 0.00024 21.4 0.0 0.00053 20.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Peptidase_S46 PF10459.9 ACL94203.1 - 0.0038 16.0 1.3 0.62 8.6 0.0 2.1 2 0 0 2 2 2 2 Peptidase S46 Peptidase_S32 PF05579.13 ACL94203.1 - 0.018 14.2 4.6 1.1 8.4 0.3 2.9 2 1 1 3 3 3 0 Equine arteritis virus serine endopeptidase S32 GRASP55_65 PF04495.14 ACL94203.1 - 0.077 13.3 0.0 0.2 12.0 0.0 1.6 2 0 0 2 2 2 0 GRASP55/65 PDZ-like domain Peptidase_S29 PF02907.15 ACL94203.1 - 0.11 12.3 0.1 0.28 10.9 0.1 1.7 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease FAD_syn PF06574.12 ACL94205.1 - 3.4e-48 163.5 0.0 4.5e-48 163.1 0.0 1.2 1 0 0 1 1 1 1 FAD synthetase Flavokinase PF01687.17 ACL94205.1 - 8e-35 119.5 0.0 1.2e-34 118.9 0.0 1.3 1 0 0 1 1 1 1 Riboflavin kinase CTP_transf_like PF01467.26 ACL94205.1 - 0.029 14.6 0.0 0.05 13.8 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase-like MaoC_dehydratas PF01575.19 ACL94206.2 - 2.5e-23 82.0 0.0 3.1e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 ACL94206.2 - 2.5e-09 37.4 0.0 4.9e-09 36.4 0.0 1.5 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase 4HBT PF03061.22 ACL94206.2 - 0.0012 19.1 0.0 0.0026 18.1 0.0 1.7 1 1 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 ACL94206.2 - 0.031 14.8 0.0 0.034 14.6 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily ProQ_C PF17516.2 ACL94206.2 - 0.1 12.0 0.2 0.46 9.9 0.0 2.0 2 0 0 2 2 2 0 ProQ C-terminal domain Hydrolase_6 PF13344.6 ACL94207.2 - 1.8e-13 50.5 0.0 6e-13 48.8 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ACL94207.2 - 1.7e-08 34.4 0.3 4e-08 33.2 0.3 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like NnrU PF07298.11 ACL94208.1 - 1.7e-51 174.8 17.2 2.2e-51 174.3 17.2 1.2 1 0 0 1 1 1 1 NnrU protein DUF3188 PF11384.8 ACL94208.1 - 0.14 11.9 0.0 0.14 11.9 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3188) PEMT PF04191.13 ACL94208.1 - 1.7 9.1 6.0 0.42 11.0 0.4 2.7 3 0 0 3 3 3 0 Phospholipid methyltransferase GIY-YIG PF01541.24 ACL94209.2 - 9.5e-15 54.6 0.1 1.2e-14 54.3 0.1 1.1 1 0 0 1 1 1 1 GIY-YIG catalytic domain T5orf172 PF10544.9 ACL94209.2 - 0.0066 17.0 0.5 0.022 15.3 0.5 1.7 1 1 0 1 1 1 1 T5orf172 domain Oxygenase-NA PF09859.9 ACL94210.1 - 1.5e-82 275.3 0.0 1.8e-82 275.0 0.0 1.1 1 0 0 1 1 1 1 Oxygenase, catalysing oxidative methylation of damaged DNA 2OG-FeII_Oxy_3 PF13640.6 ACL94210.1 - 4e-05 24.4 0.0 5.5e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DNA_binding_1 PF01035.20 ACL94211.1 - 9.9e-32 108.9 0.3 1.7e-31 108.1 0.3 1.4 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Ada_Zn_binding PF02805.16 ACL94211.1 - 2.1e-24 85.3 1.6 3.7e-24 84.5 1.6 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada Methyltransf_1N PF02870.15 ACL94211.1 - 0.23 12.3 0.0 0.36 11.7 0.0 1.2 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain EAL PF00563.20 ACL94212.1 - 7.3e-55 186.1 0.5 1.1e-54 185.5 0.5 1.3 1 0 0 1 1 1 1 EAL domain Baculo_PEP_C PF04513.12 ACL94212.1 - 0.019 15.0 1.9 0.036 14.1 1.9 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Rogdi_lz PF10259.9 ACL94212.1 - 0.044 13.2 0.6 0.066 12.7 0.6 1.2 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein RUN PF02759.19 ACL94212.1 - 0.054 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 RUN domain FlaC_arch PF05377.11 ACL94212.1 - 0.15 12.5 2.1 12 6.4 0.1 2.8 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) MCM_N PF14551.6 ACL94212.1 - 0.49 11.0 1.7 4.1 8.0 0.3 2.4 2 0 0 2 2 2 0 MCM N-terminal domain Laminin_II PF06009.12 ACL94212.1 - 0.67 10.0 4.5 0.57 10.2 1.2 2.1 2 0 0 2 2 2 0 Laminin Domain II DUF1664 PF07889.12 ACL94212.1 - 1.5 8.8 3.4 5.9 7.0 2.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FeoA PF04023.14 ACL94213.3 - 4.5e-25 87.7 1.7 5.3e-25 87.5 1.7 1.1 1 0 0 1 1 1 1 FeoA domain FeoB_N PF02421.18 ACL94214.1 - 1.4e-51 174.1 0.0 2e-51 173.6 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Gate PF07670.14 ACL94214.1 - 1.4e-39 134.8 20.4 5.3e-29 100.8 1.2 3.0 3 0 0 3 3 3 2 Nucleoside recognition FeoB_C PF07664.12 ACL94214.1 - 5.1e-18 64.5 1.8 5.1e-18 64.5 1.8 2.6 2 0 0 2 2 2 1 Ferrous iron transport protein B C terminus MMR_HSR1 PF01926.23 ACL94214.1 - 2.1e-16 60.0 0.0 3.3e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 ACL94214.1 - 2.9e-05 23.6 0.0 4.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AIG1 PF04548.16 ACL94214.1 - 0.0004 19.8 0.0 0.00067 19.1 0.0 1.3 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 ACL94214.1 - 0.019 14.9 0.0 3.5 7.5 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase MeaB PF03308.16 ACL94214.1 - 0.08 11.9 0.1 0.58 9.1 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 ACL94214.1 - 0.21 11.8 0.0 0.35 11.1 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 ACL94214.1 - 0.25 11.4 0.1 0.62 10.1 0.0 1.6 2 0 0 2 2 2 0 Dynamin family AraC_binding_2 PF14525.6 ACL94215.2 - 3.8e-21 75.5 3.0 7.7e-21 74.5 3.0 1.5 1 0 0 1 1 1 1 AraC-binding-like domain HTH_18 PF12833.7 ACL94215.2 - 7.4e-15 55.0 0.6 1.4e-14 54.1 0.6 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 ACL94215.2 - 2e-09 37.3 0.0 1.1e-06 28.6 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_31 PF13560.6 ACL94215.2 - 0.011 16.1 0.7 2 8.8 0.1 2.7 1 1 1 2 2 2 0 Helix-turn-helix domain HTH_28 PF13518.6 ACL94215.2 - 0.012 15.8 0.1 3 8.1 0.1 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain Pyr_redox_dim PF02852.22 ACL94215.2 - 0.037 14.3 0.1 0.068 13.4 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain PBECR2 PF18810.1 ACL94215.2 - 0.041 14.2 0.0 0.099 12.9 0.0 1.6 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 YmdB PF13277.6 ACL94215.2 - 0.073 12.4 0.2 0.11 11.8 0.2 1.2 1 0 0 1 1 1 0 YmdB-like protein DUF418 PF04235.12 ACL94216.2 - 9.8e-41 139.4 14.2 9.8e-41 139.4 14.2 3.5 2 1 2 4 4 4 1 Protein of unknown function (DUF418) Trp_oprn_chp PF09534.10 ACL94216.2 - 0.12 12.1 11.1 0.35 10.7 1.3 2.6 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Tetraspanin PF00335.20 ACL94216.2 - 1.1 8.9 8.7 0.12 12.1 3.3 2.0 1 1 1 2 2 2 0 Tetraspanin family 3HCDH_N PF02737.18 ACL94217.1 - 1.2e-57 194.8 0.1 1.4e-57 194.5 0.1 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 ACL94217.1 - 2.9e-34 117.6 0.0 8.3e-34 116.1 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 ACL94217.1 - 5e-05 23.5 0.6 0.00011 22.4 0.6 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 ACL94217.1 - 0.0024 17.3 0.5 0.0049 16.3 0.5 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 ACL94217.1 - 0.049 14.2 1.3 0.12 12.9 1.2 1.8 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 ACL94217.1 - 0.057 13.4 0.2 0.098 12.6 0.2 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 ACL94217.1 - 0.12 12.0 0.9 0.25 11.0 0.4 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Queuosine_synth PF02547.15 ACL94217.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein Radical_SAM PF04055.21 ACL94218.2 - 9.2e-11 42.4 0.0 2.1e-10 41.2 0.0 1.5 1 1 0 1 1 1 1 Radical SAM superfamily LAM_C PF12544.8 ACL94218.2 - 1.4e-08 35.0 0.1 2.4e-08 34.2 0.1 1.4 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Fer4_12 PF13353.6 ACL94218.2 - 3.4e-05 24.1 0.0 5.3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 ACL94218.2 - 9.5e-05 22.5 0.0 0.00015 21.9 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain VIT1 PF01988.19 ACL94219.2 - 1.3e-54 185.3 14.2 1.5e-54 185.1 14.2 1.0 1 0 0 1 1 1 1 VIT family MiaE_2 PF13794.6 ACL94219.2 - 0.013 15.2 0.1 0.024 14.3 0.1 1.4 1 1 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like TerB PF05099.13 ACL94220.1 - 2.7e-13 50.1 3.1 3.5e-13 49.7 3.1 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TerB DUF533 PF04391.12 ACL94220.1 - 0.015 14.8 1.5 0.045 13.3 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF533) Sbi-IV PF11621.8 ACL94220.1 - 0.081 13.3 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 C3 binding domain 4 of IgG-bind protein SBI zf-HC2 PF13490.6 ACL94220.1 - 0.32 11.3 3.8 11 6.4 0.2 3.4 3 1 0 3 3 3 0 Putative zinc-finger tRNA-synt_2 PF00152.20 ACL94222.1 - 8.8e-33 113.7 0.0 1.2e-32 113.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 ACL94222.1 - 0.029 13.9 0.0 0.069 12.6 0.0 1.7 2 1 0 2 2 2 0 tRNA synthetases class II core domain (F) EFP PF01132.20 ACL94223.1 - 1.2e-22 79.6 0.0 1.1e-21 76.6 0.0 2.2 2 0 0 2 2 2 1 Elongation factor P (EF-P) OB domain Elong-fact-P_C PF09285.11 ACL94223.1 - 2.7e-21 75.1 1.2 5.6e-21 74.0 1.2 1.6 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP_N PF08207.12 ACL94223.1 - 2.1e-16 59.7 0.0 4.2e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain TonB_dep_Rec PF00593.24 ACL94224.1 - 1.9e-32 113.8 27.6 1.9e-32 113.8 27.6 1.9 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 ACL94224.1 - 1.3e-08 35.3 2.8 1.4e-08 35.2 1.0 2.0 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain HATPase_c PF02518.26 ACL94225.1 - 1.9e-27 96.0 0.0 1.1e-26 93.5 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ACL94225.1 - 2.9e-25 88.6 0.1 5.3e-25 87.8 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ACL94225.1 - 1.4e-17 63.5 0.5 1.4e-17 63.5 0.5 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 ACL94225.1 - 0.0061 16.4 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 ACL94225.1 - 0.1 12.6 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Bax1-I PF01027.20 ACL94225.1 - 0.13 12.0 6.8 0.21 11.4 6.8 1.2 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF4926 PF16277.5 ACL94226.1 - 2.2e-20 71.8 0.3 2.4e-20 71.6 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4926) ETF PF01012.21 ACL94228.1 - 1e-34 120.0 13.7 1.9e-34 119.1 13.7 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 ACL94228.1 - 1.1e-34 118.3 1.0 1.1e-34 118.3 1.0 2.1 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.21 ACL94229.1 - 1.2e-47 162.1 6.5 1.7e-47 161.7 6.5 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Ala_racemase_N PF01168.20 ACL94229.1 - 0.04 13.6 0.1 0.074 12.7 0.1 1.4 1 0 0 1 1 1 0 Alanine racemase, N-terminal domain Toxin_13 PF07822.11 ACL94230.2 - 0.023 14.8 1.1 0.04 14.0 1.1 1.3 1 0 0 1 1 1 0 Neurotoxin B-IV-like protein Cob_adeno_trans PF01923.18 ACL94231.1 - 5.3e-59 199.0 0.0 6.1e-59 198.8 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase DUF4140 PF13600.6 ACL94231.1 - 0.015 15.7 0.3 0.066 13.7 0.3 1.8 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) HIG_1_N PF04588.13 ACL94232.2 - 3.1e-13 49.7 2.9 3.9e-13 49.4 2.9 1.1 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF2909 PF11137.8 ACL94232.2 - 2.9e-05 23.9 4.7 3.5e-05 23.6 4.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2909) DUF373 PF04123.13 ACL94232.2 - 0.1 12.0 0.4 0.11 11.9 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF4131 PF13567.6 ACL94232.2 - 0.81 9.3 8.2 1 9.0 8.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) FixS PF03597.15 ACL94232.2 - 4.2 7.1 13.4 0.23 11.2 2.3 2.2 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type SKG6 PF08693.10 ACL94232.2 - 4.9 6.6 9.9 2.8 7.4 2.1 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain BatA PF07584.11 ACL94232.2 - 8.3 6.9 11.2 2.1 8.8 1.7 2.1 1 1 1 2 2 2 0 Aerotolerance regulator N-terminal DUF4240 PF14024.6 ACL94233.1 - 0.006 16.8 0.3 0.0081 16.3 0.2 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF4240) DUF5340 PF17275.2 ACL94233.1 - 0.04 14.0 0.1 0.052 13.7 0.1 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5340) TetR_N PF00440.23 ACL94234.1 - 3.1e-17 62.1 1.4 6.3e-17 61.1 1.4 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 ACL94234.1 - 0.00019 21.7 0.2 0.00019 21.7 0.2 2.5 1 1 2 3 3 3 1 Tetracyclin repressor-like, C-terminal domain LacI PF00356.21 ACL94234.1 - 0.0018 18.0 0.7 0.96 9.3 0.1 2.4 2 0 0 2 2 2 2 Bacterial regulatory proteins, lacI family HTH_18 PF12833.7 ACL94234.1 - 0.045 14.0 0.6 0.11 12.8 0.6 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain SseC PF04888.12 ACL94234.1 - 0.07 12.7 1.4 0.082 12.5 0.7 1.4 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family PriCT_1 PF08708.11 ACL94234.1 - 0.079 12.7 1.6 2.9 7.7 0.1 3.2 4 0 0 4 4 4 0 Primase C terminal 1 (PriCT-1) HTH_23 PF13384.6 ACL94234.1 - 0.11 12.4 1.7 0.39 10.6 0.2 2.7 3 0 0 3 3 3 0 Homeodomain-like domain TetR_N PF00440.23 ACL94235.1 - 4e-15 55.3 0.2 8e-15 54.4 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 ACL94235.1 - 0.0013 19.0 1.2 0.0017 18.6 0.1 1.8 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain LacI PF00356.21 ACL94235.1 - 0.018 14.8 1.2 0.69 9.8 0.2 2.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family TetR_C_24 PF17932.1 ACL94235.1 - 0.041 14.1 0.0 0.074 13.3 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TetR_C_29 PF17938.1 ACL94235.1 - 0.06 13.4 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain YAcAr PF10686.9 ACL94235.1 - 0.071 13.1 0.7 0.9 9.5 0.3 2.5 2 1 0 2 2 2 0 YspA, cpYpsA-related SLOG family DUF4219 PF13961.6 ACL94237.2 - 0.23 11.2 0.2 0.36 10.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) Peptidase_M20 PF01546.28 ACL94238.2 - 5.7e-37 127.4 0.5 1e-36 126.6 0.5 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ACL94238.2 - 1.3e-18 66.9 0.0 4.6e-18 65.1 0.0 2.0 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 ACL94238.2 - 6e-05 22.8 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Rieske PF00355.26 ACL94239.1 - 1.1e-17 63.8 0.0 1.9e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 ACL94239.1 - 4.5e-09 36.2 0.0 1.9e-08 34.1 0.0 1.9 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Aminotran_1_2 PF00155.21 ACL94240.1 - 6.6e-60 203.2 0.0 7.5e-60 203.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 ACL94240.1 - 1.1e-06 27.8 0.0 1.7e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 ACL94240.1 - 2.9e-05 23.6 0.0 4.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 ACL94240.1 - 3.4e-05 22.6 0.0 5.2e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme CarboxypepD_reg PF13620.6 ACL94241.1 - 9.3e-17 61.1 3.9 3.1e-16 59.4 3.9 2.0 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 ACL94241.1 - 0.00013 21.9 0.1 0.0003 20.7 0.1 1.7 1 0 0 1 1 1 1 CarboxypepD_reg-like domain Plug PF07715.15 ACL94241.1 - 0.00097 19.7 1.2 0.00097 19.7 1.2 3.7 6 0 0 6 6 6 1 TonB-dependent Receptor Plug Domain TonB_dep_Rec PF00593.24 ACL94241.1 - 3.1 7.6 56.9 40 3.9 53.0 4.0 1 1 1 2 2 2 0 TonB dependent receptor EAL PF00563.20 ACL94242.2 - 2e-71 240.3 0.1 3e-71 239.7 0.1 1.3 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 ACL94242.2 - 1.3e-43 148.5 0.0 2.5e-43 147.6 0.0 1.5 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_4 PF08448.10 ACL94242.2 - 2.8e-07 30.7 0.1 8.4e-07 29.2 0.1 1.8 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 ACL94242.2 - 0.00093 19.4 0.0 0.0017 18.6 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 ACL94242.2 - 0.0028 17.6 0.0 0.0066 16.4 0.0 1.6 1 0 0 1 1 1 1 PAS fold GTP_EFTU PF00009.27 ACL94243.1 - 7.4e-54 182.2 0.0 1.5e-53 181.2 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 ACL94243.1 - 8.6e-19 67.4 0.0 1.5e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ACL94243.1 - 2.4e-11 43.8 0.3 1e-10 41.8 0.3 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ACL94243.1 - 0.0002 21.4 0.0 0.00046 20.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 ACL94243.1 - 0.0013 18.0 0.0 0.0039 16.5 0.0 1.7 2 0 0 2 2 2 1 Septin EFG_II PF14492.6 ACL94243.1 - 0.02 15.0 0.0 0.071 13.2 0.0 1.9 2 0 0 2 2 2 0 Elongation Factor G, domain II AAA_33 PF13671.6 ACL94243.1 - 0.05 13.8 1.0 0.71 10.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain TonB_C PF03544.14 ACL94244.2 - 9.8e-09 35.5 0.0 1.4e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal FGase PF05013.12 ACL94245.1 - 8.7e-70 235.3 0.3 1e-69 235.0 0.3 1.1 1 0 0 1 1 1 1 N-formylglutamate amidohydrolase Response_reg PF00072.24 ACL94246.1 - 6.2e-21 74.7 0.0 7e-21 74.5 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain ABG_transport PF03806.13 ACL94247.2 - 2.3e-219 728.8 26.4 2.6e-219 728.6 26.4 1.0 1 0 0 1 1 1 1 AbgT putative transporter family DcuC PF03606.15 ACL94247.2 - 5.6e-08 31.7 22.3 7.1e-08 31.3 22.3 1.2 1 0 0 1 1 1 1 C4-dicarboxylate anaerobic carrier SCFA_trans PF02667.14 ACL94247.2 - 1.7e-05 24.0 8.3 1.7e-05 24.0 8.3 2.0 2 0 0 2 2 2 1 Short chain fatty acid transporter Peptidase_M10_C PF08548.11 ACL94248.1 - 1.3e-45 155.7 4.0 1.3e-45 155.7 4.0 1.7 2 0 0 2 2 2 1 Peptidase M10 serralysin C terminal Peptidase_M10 PF00413.24 ACL94248.1 - 4.5e-07 29.8 0.0 1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Matrixin HemolysinCabind PF00353.19 ACL94248.1 - 1.1e-06 28.5 11.0 4.3e-06 26.6 11.0 2.2 1 0 0 1 1 1 1 RTX calcium-binding nonapeptide repeat (4 copies) Reprolysin_5 PF13688.6 ACL94248.1 - 2.1e-05 24.8 1.1 5.8e-05 23.3 1.1 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M57 PF12388.8 ACL94248.1 - 0.0001 22.0 0.1 0.00021 21.0 0.1 1.4 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Reprolysin_3 PF13582.6 ACL94248.1 - 0.00011 22.7 2.0 0.0043 17.6 0.1 2.6 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 ACL94248.1 - 0.00028 20.6 2.2 0.00075 19.2 2.2 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 ACL94248.1 - 0.0083 16.0 1.3 0.015 15.2 1.3 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.13 ACL94248.1 - 0.017 15.0 0.4 0.044 13.7 0.4 1.6 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A OMP_b-brl PF13505.6 ACL94249.1 - 4.4e-17 62.8 8.9 9.4e-17 61.7 8.9 1.6 1 0 0 1 1 1 1 Outer membrane protein beta-barrel domain OmpA PF00691.20 ACL94249.1 - 1.7e-16 60.3 0.0 2.6e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 OmpA family Opacity PF02462.15 ACL94249.1 - 0.0006 19.9 0.1 0.0076 16.3 0.0 2.8 1 1 1 2 2 2 1 Opacity family porin protein Surface_Ag_2 PF01617.17 ACL94249.1 - 0.0011 18.4 0.0 0.006 16.0 0.0 2.1 1 1 0 1 1 1 1 Surface antigen PagL PF09411.10 ACL94249.1 - 0.067 13.3 0.3 3.6 7.7 0.0 2.9 3 0 0 3 3 3 0 Lipid A 3-O-deacylase (PagL) DEC-1_N PF04625.13 ACL94249.1 - 0.78 8.7 8.4 1.2 8.1 8.4 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Methyltransf_30 PF05430.11 ACL94250.2 - 8.2e-41 138.8 0.0 1.3e-40 138.1 0.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-methionine-dependent methyltransferase DAO PF01266.24 ACL94250.2 - 1.6e-29 103.6 13.7 3e-29 102.7 13.7 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ACL94250.2 - 7e-06 25.5 2.7 1.3e-05 24.6 0.8 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ACL94250.2 - 2.4e-05 24.5 7.7 0.00013 22.1 1.7 3.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ACL94250.2 - 0.001 19.6 0.7 0.0024 18.4 0.7 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.6 ACL94250.2 - 0.0014 19.2 0.2 0.003 18.1 0.2 1.6 1 0 0 1 1 1 1 XdhC Rossmann domain AlaDh_PNT_C PF01262.21 ACL94250.2 - 0.011 15.1 2.1 0.029 13.7 2.1 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_24 PF13578.6 ACL94250.2 - 0.011 16.7 0.0 1.7 9.7 0.0 3.0 2 1 0 2 2 2 0 Methyltransferase domain 3HCDH_N PF02737.18 ACL94250.2 - 0.026 14.4 1.0 0.047 13.6 1.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 ACL94250.2 - 0.034 13.5 0.0 0.073 12.4 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 ACL94250.2 - 0.056 12.5 2.0 0.1 11.7 2.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 ACL94250.2 - 0.077 13.0 5.5 3.5 7.6 0.6 3.5 4 0 0 4 4 4 0 FAD-NAD(P)-binding F420_oxidored PF03807.17 ACL94250.2 - 0.099 13.2 1.3 0.3 11.7 0.6 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent HI0933_like PF03486.14 ACL94250.2 - 0.13 10.9 3.2 0.24 10.0 3.2 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 ACL94250.2 - 0.54 9.5 2.6 0.76 9.0 2.6 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ACL94250.2 - 0.88 8.6 12.3 0.048 12.7 6.2 2.0 2 1 1 3 3 3 0 FAD binding domain MotA_ExbB PF01618.16 ACL94252.1 - 7.8e-14 51.5 0.2 1.6e-13 50.5 0.2 1.5 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family DUF726 PF05277.12 ACL94252.1 - 0.043 12.7 10.0 0.4 9.6 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF726) MFS_1 PF07690.16 ACL94253.2 - 2.9e-40 138.3 61.0 2.9e-36 125.1 38.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ACL94253.2 - 5.7e-06 25.5 3.7 5.7e-06 25.5 3.7 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 ACL94253.2 - 3.3 5.9 5.2 5 5.3 0.4 2.5 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family HTH_Crp_2 PF13545.6 ACL94254.1 - 1.8e-19 69.5 1.7 1.8e-19 69.5 1.7 1.7 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain Crp PF00325.20 ACL94254.1 - 1.8e-17 62.7 0.2 6e-17 61.0 0.1 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, crp family cNMP_binding PF00027.29 ACL94254.1 - 2.8e-14 52.9 0.1 4.6e-14 52.3 0.1 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain MarR_2 PF12802.7 ACL94254.1 - 0.001 18.9 0.7 0.001 18.9 0.7 1.9 2 1 0 2 2 2 1 MarR family MarR PF01047.22 ACL94254.1 - 0.002 18.0 0.2 0.0066 16.4 0.0 1.8 2 0 0 2 2 2 1 MarR family HTH_IclR PF09339.10 ACL94254.1 - 0.0067 16.2 1.1 0.024 14.4 0.2 2.3 3 0 0 3 3 3 1 IclR helix-turn-helix domain HTH_20 PF12840.7 ACL94254.1 - 0.022 14.8 0.2 0.022 14.8 0.2 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_24 PF13412.6 ACL94254.1 - 0.031 13.8 0.0 0.085 12.4 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 ACL94254.1 - 0.033 14.1 0.0 0.07 13.1 0.0 1.5 1 0 0 1 1 1 0 HTH domain HTH_36 PF13730.6 ACL94254.1 - 0.086 12.8 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Glyco_trans_1_4 PF13692.6 ACL94257.2 - 2.9e-18 66.6 0.1 7.1e-18 65.3 0.1 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 ACL94257.2 - 4.6e-17 62.1 0.0 7e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ACL94257.2 - 4.3e-13 49.6 6.2 4.7e-13 49.5 3.0 2.3 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 ACL94257.2 - 2.8e-07 31.1 9.1 2.8e-07 31.1 9.1 2.8 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 ACL94257.2 - 0.00064 20.1 0.1 0.0017 18.7 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ACL94258.1 - 1.9e-26 93.1 0.0 5.3e-26 91.6 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 ACL94258.1 - 6.8e-25 87.6 0.0 1.1e-24 86.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ACL94258.1 - 1.8e-22 80.1 0.2 3.5e-22 79.2 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 ACL94258.1 - 2e-14 54.3 4.4 2e-14 54.3 4.4 2.5 1 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 ACL94258.1 - 3.5e-09 36.9 0.0 6.8e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 baeRF_family2 PF18844.1 ACL94258.1 - 0.045 13.8 0.0 0.16 12.1 0.0 1.9 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 2 LptF_LptG PF03739.14 ACL94259.1 - 5.6e-60 203.1 6.1 6.7e-60 202.8 6.1 1.0 1 0 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG DUF3522 PF12036.8 ACL94259.1 - 0.56 10.5 3.2 1.2 9.4 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3522) Response_reg PF00072.24 ACL94260.1 - 4.6e-28 97.6 0.2 9.1e-28 96.7 0.0 1.5 2 0 0 2 2 2 1 Response regulator receiver domain GerE PF00196.19 ACL94260.1 - 1.8e-19 69.0 0.1 2.7e-19 68.5 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 ACL94260.1 - 3e-06 26.8 0.1 5.8e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 FleQ PF06490.11 ACL94260.1 - 9.6e-06 25.9 0.0 1.4e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ HTH_23 PF13384.6 ACL94260.1 - 0.0019 18.0 0.0 0.0035 17.1 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 ACL94260.1 - 0.032 14.4 0.0 0.062 13.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 ACL94260.1 - 0.063 12.8 0.1 0.19 11.3 0.1 1.9 1 1 0 1 1 1 0 Sigma-70, region 4 Sigma70_ECF PF07638.11 ACL94260.1 - 0.065 13.1 0.1 0.093 12.6 0.1 1.3 1 0 0 1 1 1 0 ECF sigma factor HTH_29 PF13551.6 ACL94260.1 - 0.11 12.5 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn helix HATPase_c PF02518.26 ACL94261.2 - 4.5e-22 78.7 0.0 8.9e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 ACL94261.2 - 2.9e-18 65.9 0.0 1.1e-17 64.1 0.0 2.0 2 0 0 2 2 2 1 PAS fold HisKA PF00512.25 ACL94261.2 - 3.8e-09 36.5 0.9 3.8e-09 36.5 0.9 2.4 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 ACL94261.2 - 4.7e-08 33.3 1.4 3.9e-07 30.3 0.0 2.7 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.7 ACL94261.2 - 1.5e-07 31.2 0.0 4.3e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 ACL94261.2 - 2.7e-07 30.8 0.0 7.5e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 PAS domain DUF4118 PF13493.6 ACL94261.2 - 0.0012 18.6 11.6 0.0027 17.5 11.6 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4118) HATPase_c_5 PF14501.6 ACL94261.2 - 0.016 15.1 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 GHKL domain HATPase_c_3 PF13589.6 ACL94261.2 - 0.033 14.0 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ABC_tran PF00005.27 ACL94263.1 - 4.6e-18 66.0 0.0 9.3e-18 65.1 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ACL94263.1 - 9e-06 25.7 0.0 0.012 15.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ACL94263.1 - 0.00073 20.0 0.3 0.00073 20.0 0.3 3.2 2 1 1 3 3 3 1 AAA ATPase domain ABC_membrane PF00664.23 ACL94263.1 - 0.00096 18.9 0.2 0.0013 18.5 0.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 ACL94263.1 - 0.0049 16.3 0.0 0.37 10.2 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 ACL94263.1 - 0.013 15.5 0.2 0.02 14.8 0.2 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_22 PF13401.6 ACL94263.1 - 0.022 15.1 0.0 0.061 13.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 ACL94263.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 ACL94263.1 - 0.47 10.7 2.6 0.88 9.8 0.1 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 ACL94264.1 - 5e-24 85.4 0.0 2e-23 83.4 0.0 1.9 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 ACL94264.1 - 1.1e-16 61.3 6.1 1.7e-16 60.7 6.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.6 ACL94264.1 - 4.1e-11 43.2 2.5 3.7e-06 27.0 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ACL94264.1 - 1.6e-10 40.8 0.0 2e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 ACL94264.1 - 3.9e-05 23.5 0.0 0.17 11.5 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 ACL94264.1 - 0.00011 22.2 0.0 0.00024 21.0 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 ACL94264.1 - 0.0014 18.3 0.5 0.0034 17.1 0.5 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Dynamin_N PF00350.23 ACL94264.1 - 0.0047 17.0 0.2 0.0083 16.2 0.2 1.3 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 ACL94264.1 - 0.0062 16.6 0.1 0.013 15.6 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 ACL94264.1 - 0.01 16.2 0.3 0.01 16.2 0.3 2.5 2 1 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 ACL94264.1 - 0.038 14.5 0.1 0.061 13.8 0.1 1.2 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 ACL94264.1 - 0.082 13.1 0.7 2.4 8.5 0.7 3.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Cyt_bd_oxida_I PF01654.17 ACL94265.1 - 2.9e-172 573.0 27.6 3.3e-172 572.8 27.6 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit I Thermopsin PF05317.11 ACL94265.1 - 0.022 14.2 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 Thermopsin DUF3099 PF11298.8 ACL94265.1 - 0.025 14.7 3.6 0.025 14.7 3.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) Cyt_bd_oxida_II PF02322.15 ACL94266.1 - 4.3e-106 354.7 32.2 4.9e-106 354.5 32.2 1.0 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II SLATT_5 PF18160.1 ACL94266.1 - 4.2 6.7 5.0 2.3 7.5 1.6 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 YbgT_YccB PF08173.11 ACL94267.1 - 6.2e-16 58.2 9.4 6.9e-16 58.1 9.4 1.1 1 0 0 1 1 1 1 Membrane bound YbgT-like protein CheW PF01584.19 ACL94268.2 - 7.6e-34 116.3 0.2 8.9e-34 116.1 0.2 1.0 1 0 0 1 1 1 1 CheW-like domain DUF3850 PF12961.7 ACL94269.1 - 2.7e-27 94.6 0.0 3.9e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3850) ASCH PF04266.14 ACL94269.1 - 1.5e-05 25.5 0.0 1.9e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 ASCH domain MMR_HSR1 PF01926.23 ACL94270.2 - 1.2e-20 73.7 0.0 1.8e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ACL94270.2 - 4.2e-08 33.3 0.0 0.00017 21.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 ACL94270.2 - 4.2e-07 29.6 0.0 5.3e-07 29.3 0.0 1.3 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 ACL94270.2 - 8.8e-05 22.6 0.0 0.024 14.7 0.1 2.3 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 ACL94270.2 - 0.00015 21.4 0.0 0.029 13.9 0.1 3.0 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain Septin PF00735.18 ACL94270.2 - 0.00069 19.0 0.3 0.037 13.3 0.3 2.2 1 1 0 1 1 1 1 Septin SRPRB PF09439.10 ACL94270.2 - 0.02 14.3 0.0 0.028 13.8 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit cobW PF02492.19 ACL94270.2 - 0.028 14.0 0.3 0.096 12.3 0.2 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ras PF00071.22 ACL94270.2 - 0.037 13.6 0.0 2.9 7.5 0.0 2.0 2 0 0 2 2 2 0 Ras family Roc PF08477.13 ACL94270.2 - 0.1 12.8 0.0 0.22 11.8 0.0 1.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase YidC_periplas PF14849.6 ACL94271.1 - 9.4e-84 281.6 0.1 1.5e-83 280.9 0.1 1.3 1 0 0 1 1 1 1 YidC periplasmic domain 60KD_IMP PF02096.20 ACL94271.1 - 6.8e-58 195.2 7.0 1.1e-57 194.6 7.0 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein GntP_permease PF02447.16 ACL94271.1 - 0.097 11.3 1.1 0.18 10.4 1.1 1.4 1 0 0 1 1 1 0 GntP family permease Ribonuclease_P PF00825.18 ACL94272.1 - 9e-20 70.8 0.1 1.1e-19 70.5 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease P Toprim_2 PF13155.6 ACL94272.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.5 1 1 0 1 1 1 0 Toprim-like Semialdhyde_dh PF01118.24 ACL94272.1 - 0.15 12.5 0.0 0.2 12.1 0.0 1.2 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Ribosomal_L34 PF00468.17 ACL94273.1 - 7.2e-23 80.3 11.7 7.7e-23 80.2 11.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L34 ADH_zinc_N PF00107.26 ACL94274.1 - 1.3e-25 89.8 0.5 1.3e-25 89.8 0.5 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ACL94274.1 - 1.7e-14 55.0 0.0 5.9e-14 53.3 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ACL94274.1 - 3e-11 43.1 0.0 1.5e-10 40.9 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 ACL94274.1 - 0.0023 17.4 0.6 0.0044 16.5 0.5 1.5 2 0 0 2 2 2 1 short chain dehydrogenase AlaDh_PNT_C PF01262.21 ACL94274.1 - 0.006 15.9 2.2 0.006 15.9 2.2 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.21 ACL94274.1 - 0.011 15.5 0.2 0.019 14.7 0.2 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ADH_N_2 PF16884.5 ACL94274.1 - 0.031 14.2 0.0 0.076 12.9 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Abhydrolase_3 PF07859.13 ACL94275.1 - 1.2e-64 218.1 0.2 2e-64 217.4 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ACL94275.1 - 0.00086 18.3 0.0 0.0017 17.3 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.18 ACL94275.1 - 0.012 15.2 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family TetR_N PF00440.23 ACL94276.2 - 1.9e-17 62.8 1.4 2.2e-17 62.5 0.4 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family DprA_WH PF17782.1 ACL94276.2 - 0.015 15.4 0.1 0.23 11.6 0.0 2.5 2 1 0 2 2 2 0 DprA winged helix domain DUF2164 PF09932.9 ACL94277.2 - 2.6e-26 91.5 0.1 2.8e-26 91.3 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2164) FMO-like PF00743.19 ACL94278.1 - 2.3e-73 247.5 0.0 2.9e-73 247.1 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ACL94278.1 - 8.8e-19 67.9 0.0 2.2e-13 50.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ACL94278.1 - 4e-10 39.4 0.0 3.2e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ACL94278.1 - 3e-07 29.9 0.0 3.7e-05 23.0 0.0 2.4 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ACL94278.1 - 1.6e-06 28.3 0.0 1.2e-05 25.4 0.0 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ACL94278.1 - 3.6e-05 23.8 0.0 0.062 13.3 0.0 4.1 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 ACL94278.1 - 0.00093 19.7 0.0 0.81 10.3 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase CW_binding_1 PF01473.20 ACL94278.1 - 0.16 12.4 1.1 0.37 11.2 1.1 1.6 1 0 0 1 1 1 0 Putative cell wall binding repeat RPE65 PF03055.15 ACL94280.1 - 6.1e-107 358.7 0.0 6.9e-107 358.5 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein GSDH PF07995.11 ACL94282.1 - 1.6e-14 53.9 0.8 3.5e-13 49.6 0.0 2.8 3 1 0 3 3 3 1 Glucose / Sorbosone dehydrogenase NHL PF01436.21 ACL94282.1 - 5.7e-05 22.9 3.9 0.09 12.9 1.5 3.6 3 0 0 3 3 3 2 NHL repeat LPAM_2 PF13627.6 ACL94282.1 - 0.41 10.6 5.5 0.83 9.6 5.5 1.5 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site GST_N PF02798.20 ACL94283.1 - 8.5e-12 45.3 0.0 1.9e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ACL94283.1 - 4.8e-11 42.9 0.0 9.4e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ACL94283.1 - 3.7e-08 33.6 0.0 6.7e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ACL94283.1 - 2.6e-05 24.4 0.0 3.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ACL94283.1 - 0.001 19.2 0.0 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ACL94283.1 - 0.0029 17.6 0.4 0.0054 16.7 0.4 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Thiolase_N PF00108.23 ACL94285.1 - 2.4e-63 214.0 1.1 3.6e-63 213.4 1.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ACL94285.1 - 9e-42 141.6 0.2 1.8e-41 140.6 0.2 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ACL94285.1 - 0.00037 20.1 0.2 0.0016 18.1 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Dodecin PF07311.12 ACL94285.1 - 0.1 12.9 0.1 0.86 9.9 0.0 2.3 2 0 0 2 2 2 0 Dodecin HCV_env PF01539.17 ACL94286.1 - 0.23 11.1 2.4 0.27 10.9 2.0 1.4 1 1 0 1 1 1 0 Hepatitis C virus envelope glycoprotein E1 Lipase_chap PF03280.14 ACL94287.2 - 0.037 14.0 2.8 3.1 7.7 0.1 2.1 1 1 1 2 2 2 0 Proteobacterial lipase chaperone protein GerE PF00196.19 ACL94288.2 - 6.3e-13 48.1 0.0 9.1e-13 47.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 ACL94288.2 - 6.7e-09 35.3 0.2 1.2e-08 34.5 0.2 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 ACL94288.2 - 1.1e-07 31.3 0.4 1.7e-07 30.7 0.4 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_10 PF04967.12 ACL94288.2 - 1.3e-05 24.9 0.2 0.00014 21.5 0.2 2.4 1 1 0 1 1 1 1 HTH DNA binding domain HTH_23 PF13384.6 ACL94288.2 - 0.00019 21.1 0.5 0.00056 19.6 0.2 1.9 1 1 1 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.6 ACL94288.2 - 0.00066 19.4 0.1 0.0015 18.3 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_20 PF12840.7 ACL94288.2 - 0.0028 17.7 0.6 0.0083 16.2 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain LexA_DNA_bind PF01726.16 ACL94288.2 - 0.0035 17.1 0.2 0.011 15.5 0.2 1.9 1 1 0 1 1 1 1 LexA DNA binding domain HTH_24 PF13412.6 ACL94288.2 - 0.0037 16.8 0.0 0.0064 16.0 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding DUF134 PF02001.16 ACL94288.2 - 0.0038 17.8 0.0 0.0061 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF134 HTH_5 PF01022.20 ACL94288.2 - 0.008 16.0 0.1 0.031 14.1 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_Tnp_ISL3 PF13542.6 ACL94288.2 - 0.012 15.0 0.0 0.025 14.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 MarR_2 PF12802.7 ACL94288.2 - 0.015 15.2 0.1 0.044 13.7 0.1 1.9 1 0 0 1 1 1 0 MarR family HTH_29 PF13551.6 ACL94288.2 - 0.03 14.3 1.3 0.049 13.7 0.1 2.1 2 0 0 2 2 2 0 Winged helix-turn helix HTH_30 PF13556.6 ACL94288.2 - 0.043 13.6 0.2 0.097 12.5 0.2 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_50 PF18024.1 ACL94288.2 - 0.051 13.2 0.1 0.11 12.1 0.1 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_40 PF14493.6 ACL94288.2 - 0.058 13.8 0.0 0.085 13.3 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.12 ACL94288.2 - 0.061 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 HTH domain Sigma70_ECF PF07638.11 ACL94288.2 - 0.073 13.0 0.2 0.12 12.3 0.2 1.2 1 0 0 1 1 1 0 ECF sigma factor Sigma70_r3 PF04539.16 ACL94288.2 - 0.088 12.9 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 Sigma-70 region 3 RepB PF07506.11 ACL94288.2 - 0.099 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 RepB plasmid partitioning protein HTH_28 PF13518.6 ACL94288.2 - 0.099 12.8 0.1 0.099 12.8 0.1 2.0 2 1 0 2 2 1 0 Helix-turn-helix domain CENP-B_N PF04218.13 ACL94288.2 - 0.19 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain FCD PF07729.12 ACL94289.1 - 6e-23 81.6 5.9 1.1e-22 80.7 5.9 1.5 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 ACL94289.1 - 2.9e-13 49.2 0.1 5.8e-13 48.3 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 ACL94289.1 - 0.1 12.2 0.0 0.66 9.6 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding TetR_C_15 PF17918.1 ACL94289.1 - 0.31 11.8 7.9 3.3 8.5 1.7 2.6 1 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Aldolase PF01081.19 ACL94290.1 - 1.1e-27 96.8 0.8 1.4e-27 96.4 0.8 1.0 1 0 0 1 1 1 1 KDPG and KHG aldolase HMGL-like PF00682.19 ACL94290.1 - 8.4e-05 22.2 0.0 0.00016 21.3 0.0 1.5 2 0 0 2 2 2 1 HMGL-like TMP-TENI PF02581.17 ACL94290.1 - 0.012 15.0 0.1 0.041 13.2 0.1 1.9 2 0 0 2 2 2 0 Thiamine monophosphate synthase DGOK PF05035.12 ACL94291.1 - 6.1e-89 297.7 0.6 6.9e-89 297.5 0.6 1.0 1 0 0 1 1 1 1 2-keto-3-deoxy-galactonokinase TonB_dep_Rec PF00593.24 ACL94292.1 - 2.8e-31 109.9 49.8 2.8e-31 109.9 49.8 2.5 1 1 2 3 3 3 1 TonB dependent receptor Plug PF07715.15 ACL94292.1 - 4.7e-10 40.0 1.0 1.5e-09 38.3 1.0 1.9 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain Trp_halogenase PF04820.14 ACL94293.1 - 1.5e-199 663.6 0.0 1.7e-199 663.4 0.0 1.0 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_9 PF13454.6 ACL94293.1 - 0.023 14.7 0.1 0.12 12.3 0.1 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.24 ACL94293.1 - 0.036 13.7 2.6 0.33 10.5 2.6 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ACL94293.1 - 0.053 12.8 0.0 1.8 7.7 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ACL94293.1 - 0.12 11.7 0.2 17 4.6 1.3 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF5597 PF18120.1 ACL94295.1 - 5.4e-45 152.8 0.1 1e-44 151.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5597) Glyco_hydro_42 PF02449.15 ACL94295.1 - 7.5e-10 38.7 0.1 1.1e-09 38.1 0.1 1.2 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_35 PF01301.19 ACL94295.1 - 2.9e-08 33.7 0.0 8.2e-05 22.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 35 Glyco_hydro_31 PF01055.26 ACL94296.1 - 2.5e-129 432.3 6.7 3.2e-129 432.0 6.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF5110 PF17137.4 ACL94296.1 - 4.5e-19 68.5 0.1 1.1e-18 67.3 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) DUF4968 PF16338.5 ACL94296.1 - 2.5e-10 40.5 0.0 4.3e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) Gal_mutarotas_2 PF13802.6 ACL94296.1 - 6.4e-06 26.4 1.3 0.00019 21.7 0.6 3.6 3 1 0 3 3 3 1 Galactose mutarotase-like PA14 PF07691.12 ACL94296.1 - 1.7e-05 24.6 0.0 4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 PA14 domain LysR_substrate PF03466.20 ACL94297.1 - 4.1e-24 85.1 4.2 6.9e-24 84.4 4.2 1.4 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 ACL94297.1 - 4.6e-16 58.5 0.3 1e-15 57.4 0.3 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family FMN_red PF03358.15 ACL94298.1 - 3.4e-11 43.1 0.1 4.2e-11 42.8 0.1 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_5 PF12724.7 ACL94298.1 - 1.3e-09 38.4 0.0 5e-05 23.6 0.0 2.1 1 1 1 2 2 2 2 Flavodoxin domain Flavodoxin_1 PF00258.25 ACL94298.1 - 2.2e-06 27.9 0.3 1.6e-05 25.2 0.3 2.2 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.17 ACL94298.1 - 0.00027 20.7 0.0 0.00038 20.2 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold DUF3464 PF11947.8 ACL94298.1 - 0.17 11.7 0.4 0.28 10.9 0.3 1.5 1 1 0 1 1 1 0 Photosynthesis affected mutant 68 Flagellin_N PF00669.20 ACL94299.1 - 2.1e-22 79.7 18.1 2.1e-22 79.7 18.1 2.9 2 1 1 3 3 3 1 Bacterial flagellin N-terminal helical region Flagellin_C PF00700.21 ACL94299.1 - 1.3e-13 51.1 3.6 1.3e-13 51.1 3.6 3.0 3 1 1 4 4 4 1 Bacterial flagellin C-terminal helical region MapZ_EC1 PF18041.1 ACL94299.1 - 0.072 13.3 0.2 0.072 13.3 0.2 2.7 3 0 0 3 3 3 0 MapZ extracellular domain 1 HALZ PF02183.18 ACL94299.1 - 0.074 13.3 1.0 0.13 12.5 0.0 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF2203 PF09969.9 ACL94299.1 - 0.13 13.0 0.3 6 7.6 0.0 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Flagellin_N PF00669.20 ACL94300.1 - 5.8e-22 78.3 19.1 5.8e-22 78.3 19.1 3.0 2 1 1 3 3 3 1 Bacterial flagellin N-terminal helical region Flagellin_C PF00700.21 ACL94300.1 - 1.2e-12 48.0 3.1 1.2e-12 48.0 3.1 3.3 2 1 0 3 3 3 1 Bacterial flagellin C-terminal helical region HALZ PF02183.18 ACL94300.1 - 0.072 13.3 1.0 0.13 12.5 0.0 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper MapZ_EC1 PF18041.1 ACL94300.1 - 0.086 13.1 8.2 0.12 12.6 0.1 2.7 3 0 0 3 3 3 0 MapZ extracellular domain 1 Flagellin_N PF00669.20 ACL94301.1 - 3.9e-22 78.9 18.1 3.9e-22 78.9 18.1 2.9 2 1 1 3 3 3 1 Bacterial flagellin N-terminal helical region Flagellin_C PF00700.21 ACL94301.1 - 2.3e-13 50.3 3.3 2.3e-13 50.3 3.3 3.3 2 1 0 2 2 2 1 Bacterial flagellin C-terminal helical region HALZ PF02183.18 ACL94301.1 - 0.061 13.6 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper Alpha_L_fucos PF01120.17 ACL94302.1 - 2.4e-96 323.3 1.6 3.2e-96 322.8 1.6 1.2 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 ACL94302.1 - 8.6e-05 23.0 0.0 0.00016 22.2 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain TAT_signal PF10518.9 ACL94302.1 - 0.016 15.0 3.4 0.031 14.1 3.4 1.4 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Glyco_hydro_97 PF10566.9 ACL94303.2 - 1.7e-102 342.5 0.1 2.2e-102 342.1 0.1 1.1 1 0 0 1 1 1 1 Glycoside hydrolase 97 GH97_N PF14508.6 ACL94303.2 - 1.2e-57 195.1 0.0 1.6e-57 194.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl-hydrolase 97 N-terminal GH97_C PF14509.6 ACL94303.2 - 2.2e-29 101.5 0.3 6.2e-29 100.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl-hydrolase 97 C-terminal, oligomerisation Glyco_hydro_3 PF00933.21 ACL94304.1 - 9.5e-75 251.9 0.0 1.3e-74 251.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Exop_C PF18559.1 ACL94304.1 - 2.9e-37 127.9 0.0 5.8e-36 123.7 0.0 2.3 2 0 0 2 2 2 1 Galactose-binding domain-like Glyco_hydro_3_C PF01915.22 ACL94304.1 - 2.6e-32 112.4 0.0 4.1e-32 111.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain SASA PF03629.18 ACL94305.1 - 1.3e-15 57.7 0.0 5.9e-07 29.4 0.0 2.2 2 0 0 2 2 2 2 Carbohydrate esterase, sialic acid-specific acetylesterase Big_6 PF17936.1 ACL94305.1 - 0.0011 19.2 0.1 0.0029 17.8 0.1 1.7 1 0 0 1 1 1 1 Bacterial Ig domain Glyco_hydro_2_N PF02837.18 ACL94305.1 - 0.0044 17.0 0.0 0.0083 16.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain CarboxypepD_reg PF13620.6 ACL94305.1 - 0.055 13.7 0.3 0.18 12.1 0.3 1.8 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain COesterase PF00135.28 ACL94306.1 - 5.8e-89 299.3 0.0 1e-88 298.5 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ACL94306.1 - 7.3e-08 32.5 1.7 0.0074 16.2 0.2 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold TAT_signal PF10518.9 ACL94306.1 - 0.15 11.9 4.0 0.53 10.2 4.0 1.9 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Glyco_hydro_42 PF02449.15 ACL94308.1 - 0.0019 17.6 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase ParE_toxin PF05016.15 ACL94309.1 - 1.7e-14 54.2 0.0 1.8e-14 54.1 0.0 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE RHH_1 PF01402.21 ACL94310.1 - 0.00062 19.6 0.6 0.0028 17.5 0.0 2.1 2 0 0 2 2 2 1 Ribbon-helix-helix protein, copG family RHH_3 PF12651.7 ACL94310.1 - 0.035 14.1 0.1 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 Ribbon-helix-helix domain ParD PF09386.10 ACL94310.1 - 0.047 14.1 0.1 0.054 13.9 0.1 1.2 1 1 0 1 1 1 0 Antitoxin ParD Aldedh PF00171.22 ACL94311.1 - 3.1e-105 352.4 0.1 4.9e-105 351.7 0.1 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pro_dh PF01619.18 ACL94311.1 - 1.3e-85 287.6 0.1 2e-85 286.9 0.1 1.3 1 0 0 1 1 1 1 Proline dehydrogenase Pro_dh-DNA_bdg PF14850.6 ACL94311.1 - 3.3e-44 150.0 0.0 1.5e-43 147.8 0.0 2.2 2 0 0 2 2 2 1 DNA-binding domain of Proline dehydrogenase PRODH PF18327.1 ACL94311.1 - 0.00024 21.2 2.4 0.00096 19.3 2.4 2.1 1 0 0 1 1 1 1 Proline utilization A proline dehydrogenase N-terminal domain VirE_N PF08800.10 ACL94311.1 - 0.02 15.0 0.0 0.21 11.7 0.0 2.4 2 0 0 2 2 2 0 VirE N-terminal domain AsnC_trans_reg PF01037.21 ACL94312.1 - 3.2e-22 78.3 0.1 4.9e-22 77.7 0.1 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 ACL94312.1 - 1.4e-17 63.0 0.1 2.6e-17 62.1 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 ACL94312.1 - 1.3e-15 56.9 2.1 1.3e-15 56.9 2.1 1.8 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain MarR_2 PF12802.7 ACL94312.1 - 4.2e-07 29.8 0.2 6.4e-07 29.2 0.2 1.4 1 0 0 1 1 1 1 MarR family MarR PF01047.22 ACL94312.1 - 2.4e-06 27.4 0.0 3.6e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 ACL94312.1 - 0.00074 19.5 0.3 0.0017 18.4 0.1 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_IclR PF09339.10 ACL94312.1 - 0.0012 18.5 0.0 0.0049 16.6 0.0 2.0 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_39 PF14090.6 ACL94312.1 - 0.006 16.3 0.4 0.011 15.4 0.1 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 ACL94312.1 - 0.012 15.6 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain TrmB PF01978.19 ACL94312.1 - 0.019 14.8 0.0 0.2 11.6 0.0 2.2 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.12 ACL94312.1 - 0.037 14.0 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 HTH domain Fe_dep_repress PF01325.19 ACL94312.1 - 0.084 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain OEP PF02321.18 ACL94314.1 - 1.1e-51 175.4 23.6 3.5e-28 98.7 6.8 2.0 2 0 0 2 2 2 2 Outer membrane efflux protein ACR_tran PF00873.19 ACL94315.1 - 0 1344.2 17.3 0 1344.0 17.3 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 ACL94315.1 - 4.3e-12 45.6 27.4 1.3e-06 27.6 11.0 2.6 2 0 0 2 2 2 2 MMPL family SecD_SecF PF02355.16 ACL94315.1 - 1.1e-05 24.9 26.7 7.7e-05 22.2 12.5 2.6 2 0 0 2 2 2 2 Protein export membrane protein Patched PF02460.18 ACL94315.1 - 3.8 5.5 23.3 0.014 13.5 13.8 1.6 2 0 0 2 2 2 0 Patched family HlyD_D23 PF16576.5 ACL94316.1 - 3e-18 65.8 1.8 6e-18 64.8 1.8 1.5 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 ACL94316.1 - 2.1e-13 50.9 4.7 1.4e-07 32.2 0.1 2.7 2 1 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 ACL94316.1 - 5e-10 39.1 4.9 2.8e-08 33.5 2.6 3.4 2 1 0 2 2 2 1 Biotin-lipoyl like HlyD PF00529.20 ACL94316.1 - 3e-05 23.8 19.1 5.4e-05 23.0 19.1 1.8 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS LPAM_2 PF13627.6 ACL94316.1 - 0.0033 17.2 2.9 0.0099 15.7 2.9 1.9 1 0 0 1 1 1 1 Prokaryotic lipoprotein-attachment site Biotin_lipoyl PF00364.22 ACL94316.1 - 0.022 14.6 0.1 0.61 10.0 0.0 2.7 3 0 0 3 3 3 0 Biotin-requiring enzyme DUF1344 PF07076.11 ACL94316.1 - 0.024 14.5 0.1 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) TetR_N PF00440.23 ACL94317.1 - 3.1e-15 55.7 0.5 3.1e-15 55.7 0.5 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 ACL94317.1 - 4.3e-06 26.9 7.4 4.3e-06 26.9 7.4 1.9 2 1 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal TetR_C_31 PF17940.1 ACL94317.1 - 3e-05 24.2 8.5 3e-05 24.2 8.5 2.1 1 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain HTH_23 PF13384.6 ACL94317.1 - 4.4e-05 23.1 1.3 0.00014 21.6 0.0 2.4 3 0 0 3 3 3 1 Homeodomain-like domain TetR_C_11 PF16859.5 ACL94317.1 - 0.00054 20.2 7.3 0.0035 17.6 6.8 2.4 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_15 PF17918.1 ACL94317.1 - 0.0026 18.5 4.5 0.0026 18.5 4.5 1.8 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain HTH_3 PF01381.22 ACL94317.1 - 0.0087 16.1 0.0 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix SVIP PF15811.5 ACL94317.1 - 0.017 15.6 0.2 0.017 15.6 0.2 2.5 2 0 0 2 2 2 0 Small VCP/p97-interacting protein HTH_7 PF02796.15 ACL94317.1 - 0.02 14.9 0.0 0.044 13.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_IclR PF09339.10 ACL94317.1 - 0.091 12.6 3.6 5.2 7.0 0.0 3.3 3 0 0 3 3 3 0 IclR helix-turn-helix domain HTH_24 PF13412.6 ACL94317.1 - 0.12 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HalX PF08663.10 ACL94317.1 - 0.19 12.1 2.2 0.25 11.7 0.3 2.0 1 1 1 2 2 2 0 HalX domain Lysine_decarbox PF03641.14 ACL94318.2 - 1.3e-35 122.3 0.0 2e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 ACL94318.2 - 2e-08 34.0 0.0 7.7e-08 32.1 0.0 1.7 1 1 0 1 1 1 1 SLOG cluster4 family Beta-Casp PF10996.8 ACL94319.1 - 1.3e-22 80.2 0.0 2.1e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 ACL94319.1 - 8.4e-22 78.1 1.2 1.9e-21 77.0 0.2 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 ACL94319.1 - 3.4e-12 46.1 0.1 9e-12 44.8 0.0 1.8 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 ACL94319.1 - 1.8e-11 44.0 0.0 3.1e-10 39.9 0.0 2.4 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 ACL94319.1 - 6.1e-10 38.8 0.0 9.3e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lipase_GDSL_2 PF13472.6 ACL94320.1 - 6.6e-14 52.7 0.1 1.4e-13 51.6 0.1 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ACL94320.1 - 1.9e-05 24.8 0.0 3.3e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_43 PF04616.14 ACL94321.1 - 3.1e-86 289.3 5.1 4.1e-86 288.9 5.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 ACL94321.1 - 1e-08 35.2 0.0 1.8e-08 34.4 0.0 1.4 1 1 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Sugar_tr PF00083.24 ACL94322.2 - 3.2e-109 365.8 27.9 3.8e-109 365.5 27.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ACL94322.2 - 5.1e-31 107.9 40.9 5.1e-31 107.9 40.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5357 PF17310.2 ACL94322.2 - 8.5 4.8 8.3 0.2 10.2 0.9 2.1 3 0 0 3 3 3 0 Family of unknown function (DUF5357) OMP_b-brl_3 PF14905.6 ACL94323.1 - 6.9e-86 288.8 7.6 1.4e-82 277.9 7.5 2.0 2 0 0 2 2 2 2 Outer membrane protein beta-barrel family TonB_dep_Rec PF00593.24 ACL94323.1 - 1.1e-22 81.6 43.8 6.5e-21 75.8 43.7 2.5 1 1 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 ACL94323.1 - 3e-10 40.6 1.2 3e-10 40.6 1.2 2.6 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain BON PF04972.17 ACL94323.1 - 0.015 15.6 0.3 1.6 9.1 0.0 2.9 2 0 0 2 2 2 0 BON domain Acetyltransf_1 PF00583.25 ACL94324.2 - 2.4e-08 34.2 0.3 7.1e-08 32.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family TPR_12 PF13424.6 ACL94324.2 - 2.1e-06 27.9 7.9 2.1e-06 27.9 7.9 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat Acetyltransf_10 PF13673.7 ACL94324.2 - 1.7e-05 24.7 0.0 7.6e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ACL94324.2 - 3.7e-05 23.6 0.2 0.00017 21.5 0.0 2.1 3 0 0 3 3 3 1 FR47-like protein Acetyltransf_7 PF13508.7 ACL94324.2 - 4.5e-05 23.8 0.0 0.00018 21.8 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain TPR_MalT PF17874.1 ACL94324.2 - 8.6e-05 22.1 6.2 0.00016 21.2 6.2 1.5 1 0 0 1 1 1 1 MalT-like TPR region TPR_10 PF13374.6 ACL94324.2 - 0.00093 19.0 9.0 0.0094 15.8 1.0 3.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 ACL94324.2 - 0.038 13.7 2.0 0.6 9.8 0.1 2.8 2 0 0 2 2 2 0 TPR repeat TPR_1 PF00515.28 ACL94324.2 - 0.083 12.8 1.8 1.4 8.9 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 ACL94324.2 - 0.11 13.3 1.3 0.11 13.3 1.3 5.1 3 3 2 5 5 5 0 Tetratricopeptide repeat Acetyltransf_9 PF13527.7 ACL94324.2 - 0.12 12.4 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TPR_2 PF07719.17 ACL94324.2 - 2.4 8.5 15.0 1.7 8.9 1.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4293 PF14126.6 ACL94326.2 - 0.033 14.4 5.1 0.71 10.1 1.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) PGG PF13962.6 ACL94326.2 - 0.12 12.2 2.0 0.15 11.9 0.6 1.9 1 1 1 2 2 2 0 Domain of unknown function ILVD_EDD PF00920.21 ACL94327.1 - 4.9e-149 497.3 0.0 5.6e-149 497.1 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family SHOCT PF09851.9 ACL94327.1 - 0.02 14.6 0.5 0.056 13.2 0.5 1.8 1 0 0 1 1 1 0 Short C-terminal domain SGL PF08450.12 ACL94328.1 - 3.5e-78 262.6 0.0 4.1e-78 262.4 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 ACL94328.1 - 0.00076 19.4 0.7 0.077 13.3 0.0 3.1 2 0 0 2 2 2 1 Two component regulator propeller adh_short_C2 PF13561.6 ACL94329.1 - 1.3e-50 172.2 0.0 1.6e-50 171.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ACL94329.1 - 3.2e-43 147.5 0.0 3.8e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 ACL94329.1 - 2e-05 24.1 0.0 0.00026 20.5 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 ACL94329.1 - 0.00043 20.2 0.0 0.00065 19.7 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 ACL94329.1 - 0.13 11.7 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Glyco_transf_4 PF13439.6 ACL94329.1 - 0.13 12.2 0.0 8.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase Family 4 3HCDH_N PF02737.18 ACL94329.1 - 0.14 12.0 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Aldedh PF00171.22 ACL94330.1 - 4.6e-154 513.3 1.6 5.5e-154 513.1 1.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FAA_hydrolase PF01557.18 ACL94331.1 - 0.00033 20.4 0.0 0.00051 19.8 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family N6_Mtase PF02384.16 ACL94334.1 - 6.4e-05 22.4 0.0 0.00016 21.1 0.0 1.6 1 0 0 1 1 1 1 N-6 DNA Methylase DUF1178 PF06676.11 ACL94335.1 - 1.4e-53 181.3 0.0 1.9e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1178) Zn-ribbon_8 PF09723.10 ACL94335.1 - 0.0012 18.9 0.0 0.0024 18.0 0.0 1.6 1 0 0 1 1 1 1 Zinc ribbon domain CN_hydrolase PF00795.22 ACL94336.1 - 1.5e-50 171.9 0.0 1.7e-50 171.8 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Glutaredoxin PF00462.24 ACL94337.1 - 4.1e-23 81.4 0.0 5e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 ACL94337.1 - 0.00015 22.1 0.0 0.00017 22.0 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain SH3BGR PF04908.15 ACL94337.1 - 0.0085 16.2 0.0 0.014 15.5 0.0 1.3 1 1 0 1 1 1 1 SH3-binding, glutamic acid-rich protein DUF836 PF05768.14 ACL94337.1 - 0.011 16.2 0.0 0.013 15.9 0.0 1.3 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) GST_N_2 PF13409.6 ACL94337.1 - 0.13 12.6 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.6 ACL94337.1 - 0.19 12.2 0.0 0.41 11.1 0.0 1.5 1 1 1 2 2 2 0 Thioredoxin-like domain Pribosyltran PF00156.27 ACL94338.2 - 9.4e-09 35.0 0.2 2e-08 33.9 0.0 1.5 2 0 0 2 2 2 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 ACL94338.2 - 0.007 15.9 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase PRTase_3 PF15610.6 ACL94338.2 - 0.023 13.9 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 PRTase ComF-like DZR PF12773.7 ACL94338.2 - 0.19 11.8 2.2 0.35 10.9 2.2 1.3 1 0 0 1 1 1 0 Double zinc ribbon Methyltransf_11 PF08241.12 ACL94339.1 - 2.5e-11 44.0 0.0 6.2e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ACL94339.1 - 1.8e-07 31.1 0.0 2.9e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ACL94339.1 - 1.8e-05 25.4 0.0 4.8e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ACL94339.1 - 0.00025 21.7 0.0 0.00089 20.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ACL94339.1 - 0.016 15.0 0.0 0.045 13.5 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 ACL94339.1 - 0.073 12.4 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 ACL94339.1 - 0.14 11.9 0.0 0.44 10.4 0.0 1.7 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_29 PF03141.16 ACL94339.1 - 0.21 10.1 0.0 0.29 9.6 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Flp_Fap PF04964.14 ACL94340.1 - 4.6e-18 64.8 1.8 5.1e-18 64.6 1.8 1.0 1 0 0 1 1 1 1 Flp/Fap pilin component Flp1_like PF16982.5 ACL94340.1 - 0.0032 16.8 1.5 0.0044 16.4 1.4 1.5 1 1 0 1 1 1 1 Putative Flagellin, Flp1-like, domain SNN_transmemb PF09049.10 ACL94340.1 - 0.015 15.2 3.2 0.022 14.7 3.2 1.2 1 0 0 1 1 1 0 Stannin transmembrane NUDIX_4 PF14815.6 ACL94341.1 - 5.7e-23 81.0 0.1 6.4e-23 80.8 0.1 1.0 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.28 ACL94341.1 - 7.3e-23 81.0 0.1 8.6e-23 80.8 0.1 1.0 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.6 ACL94341.1 - 0.079 12.5 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Nucleotide hydrolase DEAD PF00270.29 ACL94343.1 - 4.6e-48 163.3 0.0 8.3e-48 162.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ACL94343.1 - 2.2e-28 98.8 0.0 1e-27 96.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ACL94343.1 - 3.9e-07 30.2 0.0 7.3e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 ACL94343.1 - 7e-07 29.7 0.2 0.00029 21.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain UTP25 PF06862.12 ACL94343.1 - 0.00021 20.2 0.1 0.0024 16.7 0.0 2.5 3 1 1 4 4 4 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Helicase_RecD PF05127.14 ACL94343.1 - 0.002 18.0 0.0 0.0041 17.0 0.0 1.5 1 0 0 1 1 1 1 Helicase AAA_22 PF13401.6 ACL94343.1 - 0.067 13.5 0.0 0.17 12.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 ACL94343.1 - 0.14 12.1 0.0 0.95 9.4 0.0 2.3 2 1 0 2 2 2 0 Flavivirus DEAD domain ATP-grasp_6 PF18419.1 ACL94343.1 - 0.2 11.3 0.0 0.59 9.8 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp-like domain PAS_3 PF08447.12 ACL94344.1 - 2.2e-50 168.9 0.0 2.2e-17 63.1 0.0 3.4 3 0 0 3 3 3 3 PAS fold HWE_HK PF07536.14 ACL94344.1 - 8.6e-26 90.5 0.8 8.6e-26 90.5 0.8 2.2 3 0 0 3 3 3 1 HWE histidine kinase PAS_4 PF08448.10 ACL94344.1 - 1.1e-11 45.0 9.5 0.00037 20.7 0.1 5.2 5 0 0 5 5 5 4 PAS fold PAS PF00989.25 ACL94344.1 - 5.7e-11 42.4 0.0 0.0096 15.9 0.0 4.1 4 0 0 4 4 4 3 PAS fold HisKA_2 PF07568.12 ACL94344.1 - 2e-07 31.0 0.2 6.4e-07 29.4 0.2 1.9 1 0 0 1 1 1 1 Histidine kinase PAS_9 PF13426.7 ACL94344.1 - 0.00015 22.0 0.0 1.3 9.3 0.0 3.2 3 0 0 3 3 3 2 PAS domain HATPase_c_2 PF13581.6 ACL94344.1 - 0.0016 18.4 0.0 0.0066 16.4 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain PAS_11 PF14598.6 ACL94344.1 - 0.0069 16.5 0.0 15 5.8 0.0 3.3 3 0 0 3 3 3 2 PAS domain ABC_export PF16962.5 ACL94345.1 - 6.5e-05 21.6 7.7 6.5e-05 21.6 7.7 3.8 3 1 1 4 4 4 2 Putative ABC exporter ABC2_membrane PF01061.24 ACL94345.1 - 0.0046 16.4 11.7 0.0046 16.4 11.7 3.6 4 1 0 4 4 4 1 ABC-2 type transporter ABC_tran PF00005.27 ACL94346.1 - 1.2e-26 93.9 0.0 1.6e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ACL94346.1 - 9.8e-11 42.0 0.0 1.5e-05 25.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 ACL94346.1 - 0.0048 16.6 2.8 0.047 13.4 1.9 2.5 1 1 1 2 2 2 1 AAA domain SRP54 PF00448.22 ACL94346.1 - 0.0069 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_22 PF13401.6 ACL94346.1 - 0.007 16.7 0.2 0.057 13.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 ACL94346.1 - 0.0091 15.6 0.7 0.77 9.3 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ACL94346.1 - 0.013 15.9 0.2 0.026 14.9 0.2 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 ACL94346.1 - 0.022 15.3 0.0 0.033 14.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 ACL94346.1 - 0.039 13.4 0.0 7.5 5.9 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_27 PF13514.6 ACL94346.1 - 0.051 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 ACL94346.1 - 0.065 13.7 0.3 0.12 12.8 0.3 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 ACL94346.1 - 0.068 13.3 0.1 0.48 10.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 ACL94346.1 - 0.12 12.1 0.1 11 5.7 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_29 PF13555.6 ACL94346.1 - 0.13 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rick_17kDa_Anti PF05433.15 ACL94347.1 - 2.8e-07 30.3 19.8 2.8e-07 30.3 19.8 1.8 2 0 0 2 2 2 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 ACL94347.1 - 4.1e-07 29.9 16.0 1.1e-06 28.5 16.0 1.7 1 0 0 1 1 1 1 Glycine zipper Gly-zipper_YMGG PF13441.6 ACL94347.1 - 3.4e-05 23.5 19.2 3.4e-05 23.5 19.2 2.2 2 0 0 2 2 2 1 YMGG-like Gly-zipper DUF456 PF04306.13 ACL94347.1 - 0.0048 17.2 0.8 0.0089 16.3 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Gly-zipper_OmpA PF13436.6 ACL94347.1 - 0.072 12.9 23.9 0.061 13.1 4.3 2.8 3 0 0 3 3 3 0 Glycine-zipper domain APG6_N PF17675.1 ACL94347.1 - 0.3 11.6 0.1 0.3 11.6 0.1 2.2 3 0 0 3 3 3 0 Apg6 coiled-coil region Romo1 PF10247.9 ACL94347.1 - 0.42 11.0 6.2 4.3 7.8 0.1 2.3 1 1 1 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 TraT PF05818.12 ACL94347.1 - 0.59 9.8 6.7 0.36 10.5 4.8 1.6 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein DUF4407 PF14362.6 ACL94347.1 - 7.1 5.9 13.1 10 5.4 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Bacteriocin_IIc PF10439.9 ACL94347.1 - 7.3 6.8 13.9 23 5.2 13.9 1.9 1 1 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Methyltransf_11 PF08241.12 ACL94348.1 - 6.8e-22 77.9 0.0 1.2e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ACL94348.1 - 7.6e-22 77.9 0.0 1.1e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ACL94348.1 - 9.2e-18 64.8 0.0 1.5e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ACL94348.1 - 2.2e-16 60.4 0.0 3.5e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ACL94348.1 - 3.2e-16 59.5 0.0 4.1e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ACL94348.1 - 4.7e-09 35.9 0.0 6.5e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 ACL94348.1 - 6.2e-07 29.0 0.0 8.5e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 ACL94348.1 - 1.4e-05 24.7 0.0 2.8e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 ACL94348.1 - 0.00046 19.2 0.0 0.0007 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.13 ACL94348.1 - 0.001 18.5 0.0 0.0015 18.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 ACL94348.1 - 0.001 19.1 0.0 0.0015 18.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 ACL94348.1 - 0.0035 16.8 0.0 0.0049 16.3 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB DREV PF05219.12 ACL94348.1 - 0.0036 16.5 0.0 0.0053 15.9 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase ADH_zinc_N PF00107.26 ACL94348.1 - 0.0043 17.0 0.1 0.0093 15.9 0.1 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase NodS PF05401.11 ACL94348.1 - 0.0057 16.3 0.0 0.0082 15.8 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_PK PF05891.12 ACL94348.1 - 0.024 14.2 0.0 0.032 13.7 0.0 1.1 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase PIN PF01850.21 ACL94349.3 - 5.7e-09 36.5 0.1 6.8e-09 36.3 0.1 1.0 1 0 0 1 1 1 1 PIN domain MazE_antitoxin PF04014.18 ACL94350.1 - 0.00022 21.0 0.5 0.0005 19.9 0.1 1.7 2 0 0 2 2 2 1 Antidote-toxin recognition MazE, bacterial antitoxin HTH_23 PF13384.6 ACL94350.1 - 0.037 13.8 0.0 0.071 12.9 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain AA_kinase PF00696.28 ACL94351.1 - 7.3e-45 153.4 0.9 7.3e-45 153.4 0.9 1.4 2 0 0 2 2 2 1 Amino acid kinase family ACT_7 PF13840.6 ACL94351.1 - 2e-18 65.9 1.6 9.5e-15 54.2 1.3 2.6 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 ACL94351.1 - 1.9e-17 62.7 1.6 1.1e-10 41.1 0.1 2.5 2 0 0 2 2 2 2 ACT domain ACT_6 PF13740.6 ACL94351.1 - 0.00054 19.9 0.3 0.009 16.0 0.0 2.5 2 0 0 2 2 2 1 ACT domain NolB PF17398.2 ACL94351.1 - 0.0028 18.1 0.2 0.0091 16.4 0.2 1.8 1 0 0 1 1 1 1 Nodulation protein NolB ACT_4 PF13291.6 ACL94351.1 - 0.095 13.3 1.2 8.4 7.1 0.0 2.5 2 0 0 2 2 2 0 ACT domain LppA PF16708.5 ACL94351.1 - 0.28 11.1 2.8 0.2 11.5 0.5 1.9 2 0 0 2 2 2 0 Lipoprotein confined to pathogenic Mycobacterium CZB PF13682.6 ACL94353.1 - 1.4e-09 38.2 1.2 2.1e-09 37.7 1.2 1.3 1 0 0 1 1 1 1 Chemoreceptor zinc-binding domain Lumazine_bd_2 PF12893.7 ACL94354.2 - 5.4e-30 104.5 0.1 6.2e-30 104.3 0.1 1.0 1 0 0 1 1 1 1 Putative lumazine-binding Esterase_phd PF10503.9 ACL94355.2 - 3e-12 46.5 0.7 3e-12 46.5 0.7 2.2 2 1 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 ACL94355.2 - 0.00013 21.6 0.2 0.00021 20.8 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 ACL94355.2 - 0.0072 16.1 0.0 0.02 14.7 0.0 1.7 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase EamA PF00892.20 ACL94356.1 - 5.4e-17 62.2 32.7 2.4e-12 47.2 10.1 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF2070 PF09843.9 ACL94356.1 - 0.53 8.5 9.8 1.6 6.9 1.2 2.0 1 1 0 2 2 2 0 Predicted membrane protein (DUF2070) PEP-utilizers_C PF02896.18 ACL94357.1 - 3.3e-88 295.6 0.0 6.8e-88 294.6 0.0 1.5 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilisers_N PF05524.13 ACL94357.1 - 5e-20 71.8 2.0 7.7e-20 71.2 0.7 2.1 2 0 0 2 2 2 1 PEP-utilising enzyme, N-terminal PEP-utilizers PF00391.23 ACL94357.1 - 3.7e-18 65.0 0.0 8.6e-18 63.8 0.0 1.7 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain GAF_2 PF13185.6 ACL94357.1 - 4.8e-17 62.5 0.4 2e-16 60.5 0.1 2.3 2 0 0 2 2 2 1 GAF domain GAF PF01590.26 ACL94357.1 - 5.9e-15 56.1 0.1 3.1e-14 53.7 0.0 2.2 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 ACL94357.1 - 3.3e-06 27.5 0.0 9.4e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 GAF domain HTH_25 PF13413.6 ACL94358.1 - 1.4e-21 76.1 0.2 1.4e-21 76.1 0.2 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 ACL94358.1 - 4.8e-06 26.5 0.0 8.3e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 ACL94358.1 - 4.9e-06 26.8 0.4 1.7e-05 25.0 0.4 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain DUF4115 PF13464.6 ACL94358.1 - 0.0043 17.2 0.0 0.016 15.4 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4115) HTH_37 PF13744.6 ACL94358.1 - 0.022 14.7 0.0 0.052 13.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain GcpE PF04551.14 ACL94359.1 - 5.1e-129 430.3 0.3 6e-129 430.1 0.3 1.0 1 0 0 1 1 1 1 GcpE protein MR_MLE_C PF13378.6 ACL94359.1 - 0.0036 16.9 0.3 0.012 15.2 0.3 1.9 1 1 0 1 1 1 1 Enolase C-terminal domain-like TetR_C_1 PF02909.17 ACL94360.1 - 0.1 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain S4 PF01479.25 ACL94363.1 - 9.5e-14 50.9 0.1 2e-13 49.8 0.1 1.6 1 0 0 1 1 1 1 S4 domain PseudoU_synth_2 PF00849.22 ACL94363.1 - 9.5e-12 45.3 0.0 7.7e-11 42.3 0.0 2.1 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4_2 PF13275.6 ACL94363.1 - 0.00013 21.7 0.0 0.00058 19.6 0.0 2.0 2 0 0 2 2 2 1 S4 domain PCRF PF03462.18 ACL94364.2 - 8e-66 221.6 1.7 9.6e-66 221.3 0.3 1.7 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 ACL94364.2 - 3e-40 136.8 2.4 3e-40 136.8 2.4 1.9 2 0 0 2 2 2 1 RF-1 domain MIR PF02815.19 ACL94364.2 - 0.022 14.6 0.1 0.039 13.8 0.1 1.4 1 0 0 1 1 1 0 MIR domain NT5C PF06941.12 ACL94364.2 - 0.035 14.0 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) EAL PF00563.20 ACL94365.1 - 9.9e-71 238.0 0.0 1.5e-70 237.5 0.0 1.3 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 ACL94365.1 - 3.4e-39 134.2 0.0 5.9e-39 133.4 0.0 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain CHASE4 PF05228.13 ACL94365.1 - 6.6e-15 55.5 0.0 1.5e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 CHASE4 domain Hydrolase_4 PF12146.8 ACL94366.1 - 3.6e-08 33.0 0.7 2.3e-07 30.4 0.7 2.2 1 1 1 2 2 2 1 Serine aminopeptidase, S33 PAF-AH_p_II PF03403.13 ACL94366.1 - 0.0034 15.9 0.0 0.0054 15.3 0.0 1.3 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 ACL94366.1 - 0.014 14.3 0.0 0.027 13.4 0.0 1.6 2 0 0 2 2 2 0 Chlorophyllase enzyme FSH1 PF03959.13 ACL94366.1 - 0.059 13.0 0.0 0.41 10.3 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Peripla_BP_4 PF13407.6 ACL94367.1 - 2.1e-58 198.0 10.4 2.7e-58 197.6 10.4 1.0 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_1 PF00532.21 ACL94367.1 - 2.3e-16 60.1 2.1 2.9e-16 59.7 2.1 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_3 PF13377.6 ACL94367.1 - 8.7e-13 48.9 2.1 1.1e-11 45.3 0.2 2.1 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_6 PF13458.6 ACL94367.1 - 6.6e-11 42.5 7.1 8.8e-11 42.1 7.1 1.1 1 0 0 1 1 1 1 Periplasmic binding protein ANF_receptor PF01094.28 ACL94367.1 - 0.0019 17.4 0.1 0.056 12.5 0.0 2.1 2 0 0 2 2 2 1 Receptor family ligand binding region CytB6-F_Fe-S PF08802.10 ACL94367.1 - 0.057 13.4 1.6 0.13 12.3 1.6 1.6 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit NAD_binding_7 PF13241.6 ACL94367.1 - 0.062 13.7 0.4 3.8 8.0 0.1 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding TusA PF01206.17 ACL94367.1 - 0.13 12.1 0.0 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 Sulfurtransferase TusA ABC_tran PF00005.27 ACL94368.1 - 2.4e-48 164.1 0.0 3.4e-26 92.4 0.0 2.1 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ACL94368.1 - 7e-06 26.1 0.0 0.0023 17.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ACL94368.1 - 0.0025 17.8 0.1 0.045 13.7 0.1 2.6 3 0 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 ACL94368.1 - 0.0046 17.4 1.5 0.044 14.2 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 ACL94368.1 - 0.005 16.5 0.0 0.015 15.0 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 ACL94368.1 - 0.0061 16.8 0.1 2.5 8.4 0.0 3.5 3 1 0 3 3 3 1 AAA domain SMC_N PF02463.19 ACL94368.1 - 0.014 14.8 0.4 4.2 6.7 0.0 2.5 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain TsaE PF02367.17 ACL94368.1 - 0.019 14.9 0.9 2.4 8.2 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TniB PF05621.11 ACL94368.1 - 0.031 13.7 0.2 2.6 7.4 0.0 2.9 3 0 0 3 3 3 0 Bacterial TniB protein MMR_HSR1 PF01926.23 ACL94368.1 - 0.033 14.3 0.0 0.46 10.6 0.0 2.5 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_30 PF13604.6 ACL94368.1 - 0.033 13.9 0.0 0.033 13.9 0.0 3.0 4 1 0 4 4 4 0 AAA domain AAA_23 PF13476.6 ACL94368.1 - 0.052 14.1 0.0 0.091 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2813 PF11398.8 ACL94368.1 - 0.099 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) Zeta_toxin PF06414.12 ACL94368.1 - 0.24 10.6 0.7 2.1 7.6 0.1 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 ACL94368.1 - 0.3 10.6 4.3 0.5 9.9 1.5 2.6 2 1 0 2 2 2 0 AAA domain BPD_transp_2 PF02653.16 ACL94369.1 - 6.3e-48 163.3 45.0 6.3e-48 163.3 45.0 1.5 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component DUF4678 PF15727.5 ACL94369.1 - 2.3 7.4 4.9 3.4 6.9 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4678) Exo_endo_phos PF03372.23 ACL94370.2 - 1.4e-11 44.4 1.0 1.9e-11 43.9 1.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Haem_oxygenas_2 PF14518.6 ACL94372.1 - 1.3e-06 28.3 0.2 2e-06 27.7 0.2 1.4 1 1 0 1 1 1 1 Iron-containing redox enzyme ACP_syn_III_C PF08541.10 ACL94373.2 - 1.2e-10 41.5 0.0 3.1e-10 40.1 0.0 1.8 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.26 ACL94373.2 - 2.1e-05 24.2 0.7 0.00011 21.9 0.1 2.2 2 1 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 ACL94373.2 - 0.00017 21.4 0.0 0.0012 18.7 0.0 2.1 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 ACL94373.2 - 0.0076 15.6 0.0 0.034 13.5 0.0 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain CdiI_2 PF18593.1 ACL94373.2 - 0.081 13.6 0.0 0.14 12.8 0.0 1.3 1 0 0 1 1 1 0 CdiI immunity protein Erythro_esteras PF05139.14 ACL94375.1 - 6.8e-23 82.0 1.4 1e-22 81.5 1.4 1.2 1 0 0 1 1 1 1 Erythromycin esterase AAA_28 PF13521.6 ACL94376.1 - 8.8e-28 97.6 0.0 1e-27 97.4 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ACL94376.1 - 0.0018 18.0 0.1 0.0034 17.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain DAP3 PF10236.9 ACL94376.1 - 0.0026 17.0 0.0 0.0037 16.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_18 PF13238.6 ACL94376.1 - 0.0047 17.5 0.0 0.0069 16.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ACL94376.1 - 0.0056 17.1 0.2 0.0093 16.4 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ACL94376.1 - 0.0065 16.7 0.0 0.038 14.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 ACL94376.1 - 0.013 14.7 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 ACL94376.1 - 0.048 14.2 0.0 0.076 13.5 0.0 1.3 1 0 0 1 1 1 0 ABC transporter ATP_bind_2 PF03668.15 ACL94376.1 - 0.056 12.7 0.0 0.079 12.2 0.0 1.1 1 0 0 1 1 1 0 P-loop ATPase protein family cobW PF02492.19 ACL94376.1 - 0.057 13.0 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 ACL94376.1 - 0.068 13.3 0.0 0.09 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 ACL94376.1 - 0.097 13.0 0.1 0.18 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ACL94376.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 ACL94376.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.21 ACL94376.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 ACL94376.1 - 0.15 11.3 0.1 0.19 11.0 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 ACL94376.1 - 0.22 11.2 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Herpes_Helicase PF02689.14 ACL94376.1 - 0.27 9.1 0.0 0.33 8.8 0.0 1.1 1 0 0 1 1 1 0 Helicase Beta-lactamase PF00144.24 ACL94377.1 - 4.8e-43 147.6 4.4 9.7e-43 146.6 4.4 1.4 1 1 0 1 1 1 1 Beta-lactamase Acetyltransf_1 PF00583.25 ACL94379.1 - 8.6e-09 35.7 0.0 1.1e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ACL94379.1 - 6.3e-07 29.4 0.0 8.1e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ACL94379.1 - 0.0084 16.5 0.0 0.013 15.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ACL94379.1 - 0.062 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_4 PF13420.7 ACL94379.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Bd3614_N PF14442.6 ACL94379.1 - 0.13 12.6 0.4 0.13 12.6 0.4 1.9 3 0 0 3 3 3 0 Bd3614-like deaminase N-terminal MOSC_N PF03476.16 ACL94380.2 - 3.9e-21 75.1 0.0 7.2e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 ACL94380.2 - 6.3e-17 61.8 0.0 9.2e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 MOSC domain ParE_toxin PF05016.15 ACL94381.1 - 6.5e-22 77.9 0.1 7.2e-22 77.8 0.1 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE ParD_antitoxin PF03693.14 ACL94382.1 - 8.3e-44 147.9 0.4 9.8e-44 147.7 0.4 1.0 1 0 0 1 1 1 1 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH DUF2000 PF09391.10 ACL94382.1 - 0.024 14.5 0.0 0.028 14.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2000) PrmC_N PF17827.1 ACL94383.1 - 5.7e-20 71.7 0.1 1.2e-19 70.6 0.1 1.6 1 0 0 1 1 1 1 PrmC N-terminal domain Methyltransf_31 PF13847.6 ACL94383.1 - 2.3e-16 59.9 0.0 3.2e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ACL94383.1 - 1.5e-12 47.4 0.0 2.6e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 ACL94383.1 - 2.1e-11 44.4 0.0 2.8e-09 37.6 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ACL94383.1 - 7e-11 42.6 0.0 5e-10 39.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ACL94383.1 - 2e-06 28.4 0.0 2.4e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 ACL94383.1 - 3.3e-06 26.7 0.0 2.4e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 ACL94383.1 - 5.4e-06 26.2 0.0 9e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PCMT PF01135.19 ACL94383.1 - 1e-05 25.4 0.0 0.00078 19.2 0.0 2.2 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.18 ACL94383.1 - 8.3e-05 22.3 0.0 0.0003 20.6 0.0 1.9 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.6 ACL94383.1 - 0.00039 20.3 0.0 0.0019 18.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ACL94383.1 - 0.0081 15.5 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase N6_Mtase PF02384.16 ACL94383.1 - 0.018 14.3 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase UBA PF00627.31 ACL94383.1 - 0.023 14.6 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain Methyltransf_5 PF01795.19 ACL94383.1 - 0.027 14.0 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 MraW methylase family Methyltransf_18 PF12847.7 ACL94383.1 - 0.035 14.0 0.0 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.17 ACL94383.1 - 0.041 13.3 0.0 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_2 PF00891.18 ACL94383.1 - 0.056 12.7 0.0 0.087 12.1 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Pal1 PF08316.11 ACL94383.1 - 0.058 14.1 0.0 0.099 13.4 0.0 1.3 1 0 0 1 1 1 0 Pal1 cell morphology protein Methyltransf_15 PF09445.10 ACL94383.1 - 0.075 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Rsm22 PF09243.10 ACL94383.1 - 0.077 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 MetW PF07021.12 ACL94383.1 - 0.098 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW GA-like PF17573.2 ACL94383.1 - 0.88 9.5 0.0 0.88 9.5 0.0 2.1 3 0 0 3 3 2 0 GA-like domain DUF4167 PF13763.6 ACL94385.1 - 1.1e-31 108.7 3.5 1.1e-31 108.7 3.5 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4167) Peptidase_M48 PF01435.18 ACL94386.1 - 1.4e-45 155.5 0.0 1.8e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M48 AAA_2 PF07724.14 ACL94387.1 - 1.2e-60 204.5 0.0 1.1e-56 191.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 ACL94387.1 - 1.6e-37 127.6 2.3 1.6e-37 127.6 2.3 2.1 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 ACL94387.1 - 9e-27 93.0 0.2 3.2e-26 91.2 0.2 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.20 ACL94387.1 - 2.8e-22 78.6 16.1 1.4e-12 47.5 1.1 3.3 4 0 0 4 4 2 2 Clp amino terminal domain, pathogenicity island component AAA PF00004.29 ACL94387.1 - 5.6e-22 78.6 0.2 2.3e-11 44.2 0.0 3.3 4 0 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ACL94387.1 - 3.2e-19 69.3 0.1 8.2e-14 51.8 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ACL94387.1 - 2.3e-11 44.4 9.9 0.00014 22.3 0.0 5.0 4 2 0 5 5 3 2 AAA ATPase domain AAA_22 PF13401.6 ACL94387.1 - 4.6e-08 33.4 0.4 0.11 12.8 0.1 4.4 2 2 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 ACL94387.1 - 5.5e-08 32.7 0.0 0.00038 20.2 0.0 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_7 PF12775.7 ACL94387.1 - 4.7e-06 26.2 0.0 0.01 15.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region TniB PF05621.11 ACL94387.1 - 1.5e-05 24.5 0.0 0.016 14.7 0.0 3.6 2 1 0 2 2 2 1 Bacterial TniB protein IstB_IS21 PF01695.17 ACL94387.1 - 3.5e-05 23.6 0.0 0.28 10.9 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 ACL94387.1 - 0.00018 21.0 0.2 0.98 8.8 0.0 3.6 2 2 0 3 3 3 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 ACL94387.1 - 0.00035 20.4 0.0 3.4 7.4 0.0 4.1 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 ACL94387.1 - 0.00039 20.5 0.0 0.14 12.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 ACL94387.1 - 0.00042 20.1 0.0 0.21 11.3 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_3 PF07726.11 ACL94387.1 - 0.00081 19.3 0.0 0.29 11.0 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 ACL94387.1 - 0.001 19.7 0.1 1 9.9 0.0 3.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 ACL94387.1 - 0.0022 18.4 0.0 1.5 9.3 0.0 2.7 3 0 0 3 3 2 1 RNA helicase ATPase_2 PF01637.18 ACL94387.1 - 0.0023 17.9 0.3 6.8 6.5 0.1 3.7 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 ACL94387.1 - 0.0026 17.4 0.2 0.17 11.4 0.0 3.1 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 ACL94387.1 - 0.0027 17.9 0.0 3.7 7.8 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 ACL94387.1 - 0.0027 17.9 0.4 7.8 6.7 0.0 4.2 4 0 0 4 4 3 0 AAA domain TsaE PF02367.17 ACL94387.1 - 0.0028 17.7 0.0 2.1 8.4 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 ACL94387.1 - 0.0029 17.5 0.0 3.2 7.6 0.0 2.8 2 0 0 2 2 2 1 RsgA GTPase NACHT PF05729.12 ACL94387.1 - 0.0039 17.1 0.0 0.49 10.3 0.0 2.6 2 0 0 2 2 2 1 NACHT domain T2SSE PF00437.20 ACL94387.1 - 0.007 15.5 0.1 0.026 13.6 0.1 2.0 1 1 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 ACL94387.1 - 0.021 15.4 0.0 2.8 8.5 0.0 3.0 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 ACL94387.1 - 0.033 13.9 0.0 12 5.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 ACL94387.1 - 0.039 14.5 5.5 18 5.8 0.0 3.3 2 1 0 2 2 2 0 AAA domain DNA_pol3_delta2 PF13177.6 ACL94387.1 - 0.045 13.5 0.0 4.5 7.0 0.0 2.5 2 0 0 2 2 2 0 DNA polymerase III, delta subunit AAA_19 PF13245.6 ACL94387.1 - 0.061 13.7 0.1 3.4 8.0 0.1 3.1 3 1 0 3 3 2 0 AAA domain AAA_33 PF13671.6 ACL94387.1 - 0.073 13.2 0.0 15 5.7 0.0 3.0 2 0 0 2 2 2 0 AAA domain ExsD PF16806.5 ACL94387.1 - 0.11 12.4 0.3 0.23 11.4 0.3 1.4 1 0 0 1 1 1 0 Antiactivator protein ExsD ResIII PF04851.15 ACL94387.1 - 0.12 12.3 0.0 19 5.2 0.0 3.1 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Ras PF00071.22 ACL94387.1 - 0.15 11.7 0.0 27 4.3 0.0 2.9 3 0 0 3 3 2 0 Ras family Fez1 PF06818.15 ACL94387.1 - 0.41 11.1 4.8 1.1 9.6 4.8 1.7 1 0 0 1 1 1 0 Fez1 HTH_34 PF13601.6 ACL94389.1 - 5.1e-23 81.1 0.0 5.6e-23 80.9 0.0 1.0 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_20 PF12840.7 ACL94389.1 - 0.00035 20.6 0.0 0.00057 19.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_27 PF13463.6 ACL94389.1 - 0.0043 17.5 0.1 0.0054 17.2 0.1 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain PadR PF03551.14 ACL94389.1 - 0.031 14.2 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Rrf2 PF02082.20 ACL94389.1 - 0.056 13.8 0.1 0.076 13.4 0.1 1.1 1 0 0 1 1 1 0 Transcriptional regulator Replic_Relax PF13814.6 ACL94389.1 - 0.087 12.9 0.2 0.1 12.7 0.2 1.1 1 0 0 1 1 1 0 Replication-relaxation CrgA PF06781.12 ACL94390.1 - 0.44 10.6 0.1 0.44 10.6 0.1 2.4 2 1 1 3 3 3 0 Cell division protein CrgA BAAT_C PF08840.11 ACL94391.1 - 6.9e-35 120.9 0.0 1.3e-34 120.0 0.0 1.5 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 ACL94391.1 - 4.9e-09 36.1 0.1 0.0007 19.2 0.0 3.1 2 1 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S15 PF02129.18 ACL94391.1 - 7.7e-08 32.2 0.9 1.9e-07 30.9 0.9 1.7 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 ACL94391.1 - 6.7e-05 22.4 2.0 0.13 11.7 0.2 2.7 3 0 0 3 3 3 2 Prolyl oligopeptidase family AXE1 PF05448.12 ACL94391.1 - 0.00072 18.3 0.1 0.22 10.1 0.1 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 ACL94391.1 - 0.021 14.7 1.8 0.037 13.9 1.8 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF1350 PF07082.11 ACL94391.1 - 0.034 13.5 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1350) FCD PF07729.12 ACL94393.2 - 1.5e-22 80.3 11.4 2.7e-22 79.5 11.4 1.3 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 ACL94393.2 - 3.4e-16 58.7 1.0 8.7e-16 57.3 1.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family RibD_C PF01872.17 ACL94394.1 - 1.4e-14 54.4 0.0 2.9e-14 53.4 0.0 1.5 1 1 0 1 1 1 1 RibD C-terminal domain dCMP_cyt_deam_1 PF00383.23 ACL94394.1 - 1.1e-13 50.9 1.0 2e-13 50.1 1.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ACL94394.1 - 0.0028 17.4 0.2 0.0047 16.7 0.2 1.3 1 0 0 1 1 1 1 MafB19-like deaminase Lum_binding PF00677.17 ACL94395.1 - 1.8e-41 140.0 0.0 1.6e-19 69.7 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain DHBP_synthase PF00926.19 ACL94396.1 - 3.6e-80 268.0 1.1 4.7e-80 267.7 1.1 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase GTP_cyclohydro2 PF00925.20 ACL94396.1 - 3.9e-65 218.4 0.0 5.8e-64 214.6 0.0 2.3 2 0 0 2 2 2 1 GTP cyclohydrolase II DMRL_synthase PF00885.19 ACL94397.1 - 4.5e-47 159.4 0.0 5.1e-47 159.2 0.0 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Peptidase_M28 PF04389.17 ACL94398.2 - 7.2e-21 74.8 0.0 1.6e-20 73.7 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 ACL94398.2 - 3.7e-06 26.8 0.0 4.7e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 ACL94398.2 - 0.015 14.3 0.0 0.034 13.2 0.0 1.5 1 1 0 2 2 2 0 M42 glutamyl aminopeptidase DUF4440 PF14534.6 ACL94399.1 - 6.4e-17 61.9 0.1 8.5e-17 61.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 ACL94399.1 - 0.0035 17.9 0.5 0.0056 17.3 0.5 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 ACL94399.1 - 0.12 12.6 0.5 0.34 11.2 0.5 1.7 1 1 0 1 1 1 0 SnoaL-like domain HTH_18 PF12833.7 ACL94400.1 - 7.8e-14 51.7 0.0 3.6e-13 49.6 0.0 2.0 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 ACL94400.1 - 1.6e-07 31.3 0.0 9e-07 28.8 0.0 2.1 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family DUF4010 PF13194.6 ACL94400.1 - 0.017 14.8 9.6 0.06 13.0 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4010) DUF5337 PF17272.2 ACL94400.1 - 0.56 10.1 4.1 0.89 9.4 0.2 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5337) DUF2306 PF10067.9 ACL94401.1 - 3.5e-22 79.2 13.7 3.5e-22 79.2 13.7 1.9 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) DUF716 PF04819.12 ACL94401.1 - 0.059 13.0 12.4 0.17 11.5 1.8 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF716) Spo7 PF03907.13 ACL94401.1 - 0.094 12.2 0.0 0.25 10.8 0.0 1.7 2 0 0 2 2 2 0 Spo7-like protein DUF420 PF04238.12 ACL94401.1 - 0.16 12.2 16.0 0.36 11.1 2.6 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF420) Acetyltransf_CG PF14542.6 ACL94402.1 - 3.2e-20 72.0 0.0 4.1e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.25 ACL94402.1 - 0.00027 21.2 0.0 0.00028 21.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ACL94402.1 - 0.062 13.2 0.0 0.066 13.1 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ACL94402.1 - 0.092 12.8 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ACL94402.1 - 0.14 12.6 0.0 0.16 12.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Thiolase_N PF00108.23 ACL94403.1 - 2.9e-80 269.4 5.4 4.4e-80 268.8 5.4 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ACL94403.1 - 1.3e-45 154.0 1.7 1.3e-45 154.0 1.7 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ACL94403.1 - 0.007 16.0 3.6 0.007 16.0 3.6 3.2 2 1 1 4 4 4 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 ACL94403.1 - 0.034 14.3 0.2 0.11 12.7 0.1 2.0 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Ornatin PF02088.15 ACL94403.1 - 0.18 11.6 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 Ornatin Dodecin PF07311.12 ACL94403.1 - 2.1 8.7 4.0 1.6 9.1 0.2 2.3 2 0 0 2 2 2 0 Dodecin HxlR PF01638.17 ACL94404.1 - 7.3e-23 80.2 0.0 1.1e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_CodY PF08222.11 ACL94404.1 - 0.023 14.2 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 CodY helix-turn-helix domain HTH_20 PF12840.7 ACL94404.1 - 0.024 14.7 0.2 0.097 12.7 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain PadR PF03551.14 ACL94404.1 - 0.12 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family EAL PF00563.20 ACL94405.1 - 9.7e-63 211.9 0.4 1.6e-62 211.2 0.4 1.3 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 ACL94405.1 - 6.8e-36 123.4 0.0 1.2e-35 122.7 0.0 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain tRNA_Me_trans PF03054.16 ACL94406.2 - 1.3e-108 363.0 0.0 1.5e-108 362.8 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.21 ACL94406.2 - 0.0011 18.7 0.0 0.0017 18.1 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase ThiI PF02568.14 ACL94406.2 - 0.0042 16.7 0.0 0.013 15.1 0.0 1.9 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) NAD_synthase PF02540.17 ACL94406.2 - 0.012 14.7 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 NAD synthase QueC PF06508.13 ACL94406.2 - 0.017 14.6 0.1 0.035 13.6 0.1 1.5 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Flagellin_C PF00700.21 ACL94407.1 - 6.3e-13 48.9 2.5 6.3e-13 48.9 2.5 3.2 4 0 0 4 4 4 2 Bacterial flagellin C-terminal helical region Flagellin_N PF00669.20 ACL94407.1 - 3.5e-07 30.4 14.2 3.5e-07 30.4 14.2 3.3 1 1 1 4 4 4 1 Bacterial flagellin N-terminal helical region SCP2_2 PF13530.6 ACL94407.1 - 0.068 13.6 0.1 0.22 12.0 0.1 1.8 1 0 0 1 1 1 0 Sterol carrier protein domain Flg_bbr_C PF06429.13 ACL94408.1 - 3.8e-10 39.8 0.5 3.8e-10 39.8 0.5 3.0 3 0 0 3 3 3 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 ACL94408.1 - 3.3e-09 36.5 2.8 3.3e-09 36.5 2.8 2.6 2 0 0 2 2 2 1 Flagella basal body rod protein Nop14 PF04147.12 ACL94409.1 - 3.1 5.9 8.0 4.1 5.5 8.0 1.1 1 0 0 1 1 1 0 Nop14-like family Flg_hook PF02120.16 ACL94410.1 - 5.3e-16 58.3 0.1 9.2e-16 57.5 0.1 1.4 1 0 0 1 1 1 1 Flagellar hook-length control protein FliK FlgD_ig PF13860.6 ACL94411.1 - 7.4e-21 73.8 2.2 1.8e-20 72.6 2.2 1.6 1 0 0 1 1 1 1 FlgD Ig-like domain FlgD PF03963.14 ACL94411.1 - 8.7e-17 61.2 11.9 8.7e-17 61.2 11.9 1.7 2 0 0 2 2 2 1 Flagellar hook capping protein - N-terminal region DUF835 PF05763.12 ACL94411.1 - 0.019 14.7 0.1 0.72 9.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF835) DUF2271 PF10029.9 ACL94411.1 - 0.021 14.5 0.9 0.065 12.9 0.2 2.1 1 1 1 2 2 2 0 Predicted periplasmic protein (DUF2271) Flg_bbr_C PF06429.13 ACL94412.1 - 3.8e-17 62.2 0.2 1.6e-16 60.2 0.2 2.2 1 0 0 1 1 1 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 ACL94412.1 - 2e-10 40.3 2.2 6.4e-10 38.8 2.2 2.0 1 0 0 1 1 1 1 Flagella basal body rod protein FlaE PF07559.14 ACL94412.1 - 9.4e-10 39.1 0.2 9.4e-10 39.1 0.2 3.4 3 1 1 4 4 4 1 Flagellar basal body protein FlaE DUF1153 PF06627.11 ACL94413.2 - 2.3e-42 143.0 0.0 2.7e-42 142.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1153) HTH_28 PF13518.6 ACL94413.2 - 0.011 15.9 0.1 0.016 15.3 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 ACL94413.2 - 0.013 15.5 0.1 0.019 15.0 0.1 1.2 1 0 0 1 1 1 0 Winged helix-turn helix YscJ_FliF PF01514.17 ACL94415.1 - 1.6e-65 220.4 2.5 2.3e-65 219.9 1.3 1.9 2 0 0 2 2 2 1 Secretory protein of YscJ/FliF family YscJ_FliF_C PF08345.11 ACL94415.1 - 8.3e-42 143.1 7.1 8.3e-42 143.1 7.1 2.2 2 0 0 2 2 2 1 Flagellar M-ring protein C-terminal DUF2007 PF09413.10 ACL94415.1 - 0.068 13.3 0.0 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 Putative prokaryotic signal transducing protein RTBV_P46 PF06216.11 ACL94415.1 - 0.27 10.1 0.0 0.43 9.4 0.0 1.2 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein FliG_C PF01706.16 ACL94416.1 - 1.5e-41 140.9 10.3 4.9e-39 132.9 1.2 4.3 2 1 3 5 5 5 2 FliG C-terminal domain FliG_N PF14842.6 ACL94416.1 - 6.7e-31 106.9 4.5 3.8e-24 85.2 0.0 3.3 3 1 0 3 3 3 2 FliG N-terminal domain FliG_M PF14841.6 ACL94416.1 - 4.8e-27 94.0 1.2 9.1e-23 80.3 0.1 3.5 3 0 0 3 3 3 2 FliG middle domain MgtE_N PF03448.17 ACL94416.1 - 5.3e-10 39.8 5.8 0.024 15.2 1.1 5.0 4 1 0 4 4 4 3 MgtE intracellular N domain Gp-FAR-1 PF05823.12 ACL94416.1 - 0.04 14.3 0.1 0.27 11.6 0.0 2.4 3 1 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) FliH PF02108.16 ACL94417.1 - 0.00013 22.1 0.1 0.00023 21.2 0.1 1.4 1 0 0 1 1 1 1 Flagellar assembly protein FliH FliMN_C PF01052.20 ACL94418.1 - 8.9e-26 89.7 1.4 1.2e-25 89.3 1.4 1.2 1 0 0 1 1 1 1 Type III flagellar switch regulator (C-ring) FliN C-term Sigma54_activat PF00158.26 ACL94419.1 - 2.7e-69 232.2 0.0 4.3e-69 231.5 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 ACL94419.1 - 2e-21 76.6 0.0 2.5e-20 73.0 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain HTH_8 PF02954.19 ACL94419.1 - 2.4e-16 59.2 0.0 5.7e-16 58.0 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 ACL94419.1 - 4.4e-06 26.7 0.0 8.4e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 ACL94419.1 - 0.00032 21.1 0.0 0.00065 20.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 ACL94419.1 - 0.00036 20.4 0.0 0.00073 19.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Response_reg PF00072.24 ACL94419.1 - 0.0013 18.8 0.1 0.0043 17.2 0.1 1.8 2 0 0 2 2 2 1 Response regulator receiver domain AAA_16 PF13191.6 ACL94419.1 - 0.003 17.9 0.0 0.0062 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain HTH_Tnp_ISL3 PF13542.6 ACL94419.1 - 0.0074 15.7 0.0 0.017 14.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 MCM PF00493.23 ACL94419.1 - 0.0078 15.3 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain ADH_zinc_N PF00107.26 ACL94419.1 - 0.0093 16.0 1.6 0.12 12.4 0.0 2.4 1 1 0 2 2 2 1 Zinc-binding dehydrogenase Mg_chelatase PF01078.21 ACL94419.1 - 0.019 14.4 0.1 3.4 7.0 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 ACL94419.1 - 0.047 14.0 0.1 0.2 11.9 0.1 2.2 1 1 0 1 1 1 0 AAA domain HTH_50 PF18024.1 ACL94419.1 - 0.11 12.1 0.0 0.31 10.7 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain ATPase PF06745.13 ACL94419.1 - 0.12 11.7 0.0 0.33 10.3 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_2 PF07724.14 ACL94419.1 - 0.15 12.2 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_29 PF13555.6 ACL94419.1 - 0.17 11.7 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Myosin_head PF00063.21 ACL94419.1 - 0.24 9.6 0.0 0.34 9.1 0.0 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) FHIPEP PF00771.20 ACL94421.1 - 9.3e-255 847.2 1.4 1.1e-254 847.0 1.4 1.0 1 0 0 1 1 1 1 FHIPEP family Porin_O_P PF07396.11 ACL94422.1 - 9.6e-82 275.0 0.8 1.1e-81 274.8 0.8 1.0 1 0 0 1 1 1 1 Phosphate-selective porin O and P SlyX PF04102.12 ACL94422.1 - 0.11 13.1 2.0 0.22 12.2 2.0 1.4 1 0 0 1 1 1 0 SlyX Mito_fiss_reg PF05308.11 ACL94422.1 - 0.89 9.6 5.4 1.3 9.1 5.4 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF2236 PF09995.9 ACL94423.1 - 3e-30 106.1 2.2 5.1e-30 105.4 2.2 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) TetR_N PF00440.23 ACL94424.1 - 3.1e-17 62.1 0.6 3.1e-17 62.1 0.6 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_15 PF17918.1 ACL94424.1 - 8e-06 26.6 4.5 8e-06 26.6 4.5 3.2 2 2 1 3 3 3 1 Tetracyclin repressor-like, C-terminal domain HTH_7 PF02796.15 ACL94424.1 - 0.0093 16.0 0.0 0.023 14.8 0.0 1.7 1 1 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_3 PF01381.22 ACL94424.1 - 0.011 15.7 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix LacI PF00356.21 ACL94424.1 - 0.024 14.4 0.9 0.11 12.3 0.1 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_31 PF13560.6 ACL94424.1 - 0.083 13.2 2.6 0.33 11.3 0.6 2.7 2 1 0 2 2 2 0 Helix-turn-helix domain FCD PF07729.12 ACL94424.1 - 0.44 11.0 8.6 1.3 9.5 1.2 3.0 3 1 0 3 3 3 0 FCD domain DUF4282 PF14110.6 ACL94426.1 - 8.7e-18 64.9 3.4 1e-17 64.6 3.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4282) Phage_holin_3_6 PF07332.11 ACL94426.1 - 0.078 13.0 9.5 0.1 12.6 9.5 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Oleosin PF01277.17 ACL94426.1 - 0.24 11.2 4.9 0.47 10.2 4.9 1.5 1 1 0 1 1 1 0 Oleosin MarR PF01047.22 ACL94427.1 - 1.6e-14 53.6 0.0 2.3e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 ACL94427.1 - 7.4e-11 41.8 0.2 1.4e-10 40.9 0.2 1.4 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 ACL94427.1 - 1.7e-10 41.2 0.1 3.6e-10 40.2 0.1 1.6 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_20 PF12840.7 ACL94427.1 - 1.1e-05 25.4 0.3 2.4e-05 24.3 0.2 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HxlR PF01638.17 ACL94427.1 - 3.4e-05 23.6 0.0 4.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 HxlR-like helix-turn-helix PadR PF03551.14 ACL94427.1 - 4.4e-05 23.4 0.0 8.3e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family TrmB PF01978.19 ACL94427.1 - 0.0019 18.0 0.0 0.003 17.4 0.0 1.5 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Penicillinase_R PF03965.16 ACL94427.1 - 0.0051 17.1 0.0 0.0083 16.5 0.0 1.3 1 0 0 1 1 1 1 Penicillinase repressor HTH_IclR PF09339.10 ACL94427.1 - 0.019 14.8 0.2 0.038 13.8 0.2 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_34 PF13601.6 ACL94427.1 - 0.022 14.9 0.0 0.033 14.4 0.0 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_5 PF01022.20 ACL94427.1 - 0.06 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_28 PF13518.6 ACL94427.1 - 0.097 12.8 0.0 0.26 11.4 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain DprA_WH PF17782.1 ACL94427.1 - 0.25 11.5 3.1 0.88 9.7 1.9 2.5 1 1 1 2 2 2 0 DprA winged helix domain OsmC PF02566.19 ACL94428.1 - 1.9e-19 70.0 0.2 2.4e-19 69.7 0.2 1.1 1 0 0 1 1 1 1 OsmC-like protein DnaJ PF00226.31 ACL94430.1 - 6.5e-10 39.0 0.0 1.1e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 ACL94430.1 - 5.8e-05 23.2 0.0 0.00064 19.8 0.0 2.1 1 1 0 1 1 1 1 DnaJ C terminal domain Putative_PNPOx PF01243.20 ACL94431.1 - 6.4e-29 100.0 0.0 9.2e-29 99.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 ACL94431.1 - 5.5e-16 58.4 2.8 1e-15 57.5 2.8 1.5 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 ACL94431.1 - 9.4e-08 32.6 0.0 1.5e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 ACL94431.1 - 0.018 14.6 0.0 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like Lsr2 PF11774.8 ACL94431.1 - 0.15 12.2 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Lsr2 TetR_C_7 PF14246.6 ACL94432.1 - 4.3e-26 91.3 0.4 7.8e-26 90.4 0.4 1.4 1 0 0 1 1 1 1 AefR-like transcriptional repressor, C-terminal domain TetR_N PF00440.23 ACL94432.1 - 8.3e-15 54.3 1.2 1.6e-14 53.4 1.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_11 PF16859.5 ACL94432.1 - 0.00018 21.8 2.0 0.00018 21.8 2.0 1.6 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_24 PF17932.1 ACL94432.1 - 0.00093 19.4 0.1 0.0019 18.4 0.0 1.6 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain AAA_33 PF13671.6 ACL94433.1 - 6.8e-25 87.9 0.0 1.2e-24 87.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain APH PF01636.23 ACL94433.1 - 3.2e-16 60.0 5.1 3.2e-16 60.0 5.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family AAA_18 PF13238.6 ACL94433.1 - 3.4e-06 27.6 0.0 6.6e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 ACL94433.1 - 1.8e-05 24.1 0.0 2.8e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin CPT PF07931.12 ACL94433.1 - 0.01 15.7 2.4 0.011 15.6 0.1 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein APS_kinase PF01583.20 ACL94433.1 - 0.056 13.3 0.0 0.19 11.6 0.0 1.8 1 1 0 1 1 1 0 Adenylylsulphate kinase HATPase_c PF02518.26 ACL94434.1 - 4.5e-25 88.3 0.0 9.6e-25 87.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ACL94434.1 - 6.6e-24 84.2 0.1 1.4e-23 83.2 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ACL94434.1 - 5.4e-18 64.8 2.3 5.6e-18 64.8 0.2 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 ACL94434.1 - 0.06 13.2 0.0 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPPK_C PF12555.8 ACL94434.1 - 0.39 10.8 7.7 18 5.4 0.0 4.4 4 0 0 4 4 4 0 Thiamine pyrophosphokinase C terminal AMP-binding PF00501.28 ACL94435.1 - 2e-83 280.3 0.0 3.1e-83 279.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme DUF1499 PF07386.11 ACL94435.1 - 2e-23 83.1 0.0 2e-23 83.1 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF1499) AMP-binding_C PF13193.6 ACL94435.1 - 4.4e-16 59.6 0.0 1.5e-15 57.9 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Lactamase_B PF00753.27 ACL94436.1 - 6.8e-21 75.2 8.0 1.1e-20 74.5 6.4 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 ACL94436.1 - 6.9e-13 48.4 0.1 1.3e-12 47.5 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 ACL94436.1 - 0.00011 21.8 0.3 0.00017 21.2 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ACL94436.1 - 0.039 13.8 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain DUF442 PF04273.13 ACL94438.1 - 3.2e-48 162.4 0.1 3.8e-48 162.1 0.1 1.1 1 0 0 1 1 1 1 Putative phosphatase (DUF442) CarboxypepD_reg PF13620.6 ACL94439.1 - 1.1e-16 60.8 2.6 1.1e-16 60.8 2.6 2.2 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain TonB_dep_Rec PF00593.24 ACL94439.1 - 9.2e-12 45.6 41.0 3.1e-11 43.8 40.5 2.3 1 1 0 1 1 1 1 TonB dependent receptor CarbopepD_reg_2 PF13715.6 ACL94439.1 - 5.3e-08 32.8 0.3 1.4e-07 31.4 0.3 1.8 1 0 0 1 1 1 1 CarboxypepD_reg-like domain Big_1 PF02369.16 ACL94439.1 - 6.3e-05 22.9 0.7 0.00028 20.8 0.7 2.2 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 1) Plug PF07715.15 ACL94439.1 - 0.00033 21.2 0.8 0.0009 19.8 0.8 1.7 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain DUF1416 PF07210.12 ACL94439.1 - 0.0017 18.2 0.2 0.005 16.7 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1416) fn3_3 PF14686.6 ACL94439.1 - 0.029 14.2 0.4 0.12 12.2 0.4 2.2 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain II Dioxygenase_C PF00775.21 ACL94439.1 - 0.092 12.2 0.1 3.2 7.2 0.1 2.5 1 1 0 1 1 1 0 Dioxygenase SdrD_B PF17210.3 ACL94439.1 - 0.16 12.2 1.3 0.39 11.0 0.1 2.3 2 0 0 2 2 2 0 SdrD B-like domain Invasin_D3 PF09134.10 ACL94439.1 - 0.93 9.8 6.2 0.27 11.6 0.7 3.0 3 0 0 3 3 3 0 Invasin, domain 3 Peptidase_S49 PF01343.18 ACL94441.3 - 1e-69 233.4 0.9 5.2e-47 159.6 0.1 2.2 2 0 0 2 2 2 2 Peptidase family S49 SDH_sah PF01972.16 ACL94441.3 - 2.7e-07 29.9 0.0 5.3e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Serine dehydrogenase proteinase Ligase_CoA PF00549.19 ACL94441.3 - 2.7e-05 24.0 0.1 0.16 11.8 0.1 2.8 2 0 0 2 2 2 2 CoA-ligase CLP_protease PF00574.23 ACL94441.3 - 9.4e-05 22.4 0.3 0.087 12.7 0.1 3.2 3 0 0 3 3 3 1 Clp protease ECH_1 PF00378.20 ACL94441.3 - 0.00028 20.3 4.3 1.9 7.7 0.1 4.5 4 1 1 5 5 5 2 Enoyl-CoA hydratase/isomerase Asparaginase_C PF17763.1 ACL94441.3 - 0.0033 17.6 0.1 0.22 11.7 0.1 2.5 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain DUF4096 PF13340.6 ACL94442.1 - 1.4e-25 89.3 3.5 1.9e-25 88.9 3.5 1.2 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1_2 PF13586.6 ACL94443.1 - 1.8e-17 63.5 0.2 2.3e-17 63.2 0.2 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 ACL94443.1 - 4.4e-11 42.8 0.4 5.9e-10 39.2 0.4 1.9 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 ACL94443.1 - 2e-05 24.3 0.0 2.3e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_3 PF13612.6 ACL94443.1 - 4.2e-05 23.6 0.0 5.3e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_5 PF13546.6 ACL94443.1 - 0.007 15.7 0.1 0.0081 15.5 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease BT1 PF03092.16 ACL94443.1 - 0.047 11.9 0.0 0.05 11.8 0.0 1.0 1 0 0 1 1 1 0 BT1 family HlyD_3 PF13437.6 ACL94444.1 - 2.9e-19 69.7 4.3 1.7e-13 51.2 0.1 2.9 2 1 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 ACL94444.1 - 5.4e-19 68.3 2.9 6.9e-19 67.9 2.9 1.2 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 ACL94444.1 - 2.6e-11 43.2 2.0 1.1e-05 25.1 1.8 3.5 2 1 0 2 2 2 2 Biotin-lipoyl like Biotin_lipoyl PF00364.22 ACL94444.1 - 4.6e-07 29.6 0.0 0.0015 18.3 0.0 2.8 2 0 0 2 2 2 2 Biotin-requiring enzyme PYNP_C PF07831.13 ACL94444.1 - 0.0024 17.5 0.2 0.76 9.5 0.0 2.5 2 0 0 2 2 2 2 Pyrimidine nucleoside phosphorylase C-terminal domain QRPTase_N PF02749.16 ACL94444.1 - 0.063 13.3 0.4 3.4 7.8 0.1 2.6 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain Peptidase_M23 PF01551.22 ACL94444.1 - 0.098 12.9 0.4 19 5.6 0.0 3.3 2 1 0 2 2 2 0 Peptidase family M23 Plasmid_RAQPRD PF09686.10 ACL94444.1 - 2.5 8.4 6.7 0.6 10.4 1.3 2.2 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) MacB_PCD PF12704.7 ACL94445.1 - 2.4e-16 60.7 3.8 2.4e-16 60.7 3.8 2.1 2 0 0 2 2 2 1 MacB-like periplasmic core domain FtsX PF02687.21 ACL94445.1 - 8.8e-12 45.3 8.3 2.3e-10 40.8 2.1 3.3 3 0 0 3 3 3 1 FtsX-like permease family DUF3341 PF11821.8 ACL94445.1 - 2.1 7.9 4.5 24 4.5 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3341) LptF_LptG PF03739.14 ACL94445.1 - 8.3 5.1 11.6 0.99 8.2 6.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG ABC_tran PF00005.27 ACL94446.1 - 7e-33 114.0 0.0 9.1e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ACL94446.1 - 9.2e-10 38.8 0.1 0.0011 18.8 0.3 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ACL94446.1 - 2.6e-05 23.8 0.0 0.0039 16.6 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ACL94446.1 - 0.0012 18.6 1.2 0.002 17.8 1.2 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 ACL94446.1 - 0.0017 18.5 0.6 0.015 15.5 0.6 2.2 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 ACL94446.1 - 0.0079 15.8 2.0 0.075 12.6 2.0 2.5 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ACL94446.1 - 0.014 15.3 0.1 0.02 14.8 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 ACL94446.1 - 0.017 15.5 0.3 0.028 14.8 0.3 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 ACL94446.1 - 0.023 14.4 1.6 0.28 10.9 1.6 2.1 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 ACL94446.1 - 0.024 14.9 0.2 0.32 11.2 0.2 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 ACL94446.1 - 0.027 14.2 0.0 0.29 10.8 0.0 1.9 1 1 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 ACL94446.1 - 0.12 12.8 0.0 0.17 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain ROS_MUCR PF05443.11 ACL94447.1 - 3.1e-44 150.0 0.0 3.6e-44 149.8 0.0 1.0 1 0 0 1 1 1 1 ROS/MUCR transcriptional regulator protein HATPase_c PF02518.26 ACL94448.1 - 2.6e-29 102.0 0.0 4.4e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ACL94448.1 - 1.1e-21 77.1 0.0 1.9e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ACL94448.1 - 6.2e-18 64.6 0.1 6.2e-18 64.6 0.1 2.5 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 ACL94448.1 - 0.017 15.1 0.0 0.046 13.7 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain FleQ PF06490.11 ACL94448.1 - 0.079 13.3 0.1 0.19 12.1 0.0 1.7 2 0 0 2 2 2 0 Flagellar regulatory protein FleQ Acetyltransf_4 PF13420.7 ACL94449.1 - 2.8e-24 86.0 0.0 3.2e-24 85.8 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ACL94449.1 - 5.4e-13 49.2 0.0 6.8e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ACL94449.1 - 5e-08 33.2 0.1 7.3e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ACL94449.1 - 2.1e-06 27.7 0.0 2.9e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ACL94449.1 - 5.1e-06 27.2 0.0 6.3e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ACL94449.1 - 0.0017 18.3 0.0 0.0034 17.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_6 PF13480.7 ACL94449.1 - 0.13 12.4 0.1 0.19 11.9 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_S9_N PF02897.15 ACL94450.1 - 1.2e-81 274.6 0.1 1.7e-81 274.2 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 ACL94450.1 - 9.8e-59 198.4 0.0 1.5e-58 197.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 ACL94450.1 - 0.022 14.0 0.8 0.36 10.0 0.0 2.6 3 0 0 3 3 3 0 Serine aminopeptidase, S33 PD40 PF07676.12 ACL94450.1 - 0.049 13.6 2.7 0.41 10.7 0.4 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Trypsin_2 PF13365.6 ACL94451.1 - 1.6e-08 35.6 0.0 2.7e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 ACL94451.1 - 0.00036 20.4 0.0 0.00072 19.4 0.0 1.5 1 1 0 1 1 1 1 Trypsin CsbD PF05532.12 ACL94452.1 - 4.1e-16 58.6 12.7 4.7e-16 58.4 12.7 1.1 1 0 0 1 1 1 1 CsbD-like MT0933_antitox PF14013.6 ACL94452.1 - 0.044 14.1 12.8 14 6.1 12.8 2.2 1 1 0 1 1 1 0 MT0933-like antitoxin protein Aminotran_5 PF00266.19 ACL94453.1 - 1.1e-33 116.7 0.0 1.3e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 ACL94453.1 - 1e-10 41.3 0.0 2e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 ACL94453.1 - 4.1e-06 25.6 0.0 5.9e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 ACL94453.1 - 0.0057 16.0 0.8 0.01 15.2 0.8 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family HTH_31 PF13560.6 ACL94453.1 - 0.13 12.6 2.3 0.18 12.2 0.2 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain PepX_C PF08530.10 ACL94454.2 - 1.7e-62 211.3 0.0 3e-62 210.5 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 ACL94454.2 - 7.2e-60 202.8 0.6 1e-59 202.3 0.6 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) OsmC PF02566.19 ACL94455.1 - 5.2e-12 46.1 0.0 9.9e-12 45.2 0.0 1.4 2 0 0 2 2 2 1 OsmC-like protein MaoC_dehydratas PF01575.19 ACL94456.1 - 4.8e-21 74.6 0.0 5.7e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 ACL94456.1 - 3.7e-06 27.1 0.1 1.3e-05 25.4 0.1 1.8 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase PMAIP1 PF15150.6 ACL94456.1 - 0.16 11.9 0.6 0.34 10.8 0.2 1.8 1 1 1 2 2 2 0 Phorbol-12-myristate-13-acetate-induced NTP_transf_8 PF12281.8 ACL94457.1 - 3.4e-69 233.2 0.7 4.7e-69 232.7 0.7 1.2 1 0 0 1 1 1 1 Nucleotidyltransferase SSV1_ORF_D-335 PF07935.11 ACL94457.1 - 0.00061 20.0 0.1 0.0013 19.0 0.1 1.5 1 0 0 1 1 1 1 ORF D-335-like protein AMP-binding PF00501.28 ACL94458.1 - 2.7e-70 237.1 0.0 3.4e-70 236.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ACL94458.1 - 4.7e-18 65.9 0.2 1e-17 64.8 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Engrail_1_C_sig PF10525.9 ACL94458.1 - 1.5 8.1 3.7 0.45 9.8 0.2 1.9 2 0 0 2 2 2 0 Engrailed homeobox C-terminal signature domain GMC_oxred_N PF00732.19 ACL94459.1 - 8.3e-92 307.7 0.0 1.1e-91 307.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ACL94459.1 - 1.7e-39 135.6 0.0 2.8e-39 134.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ACL94459.1 - 1.2e-08 34.4 0.1 0.00028 20.1 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 ACL94459.1 - 1.4e-05 24.4 0.1 0.0001 21.5 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 ACL94459.1 - 4.9e-05 23.5 2.2 7.2e-05 22.9 0.2 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ACL94459.1 - 0.00021 20.7 0.1 0.0017 17.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ACL94459.1 - 0.00076 19.2 4.4 0.0033 17.1 4.3 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 ACL94459.1 - 0.0015 17.8 0.3 0.0027 17.0 0.3 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 ACL94459.1 - 0.0033 16.2 0.2 0.2 10.3 0.2 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 ACL94459.1 - 0.016 14.5 0.0 0.23 10.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 ACL94459.1 - 0.018 14.7 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 ACL94459.1 - 0.14 11.4 1.5 0.16 11.2 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 ACL94459.1 - 0.16 11.0 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A p450 PF00067.22 ACL94460.1 - 1.3e-28 100.0 0.0 1.4e-26 93.2 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 ECH_1 PF00378.20 ACL94461.1 - 2.1e-51 174.6 0.0 4.7e-51 173.5 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ACL94461.1 - 3.3e-27 95.9 0.1 2.2e-24 86.6 0.1 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase DUF2336 PF10098.9 ACL94462.1 - 1.3e-56 192.0 7.9 1.3e-56 192.0 7.9 2.3 3 0 0 3 3 3 2 Uncharacterised protein conserved in bacteria (DUF2336) ROS_MUCR PF05443.11 ACL94463.1 - 1.9e-53 179.7 0.0 2.2e-53 179.6 0.0 1.0 1 0 0 1 1 1 1 ROS/MUCR transcriptional regulator protein PAS_5 PF07310.13 ACL94464.2 - 8.3e-18 64.5 0.0 1.1e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 PAS domain PfkB PF00294.24 ACL94466.1 - 1e-58 199.0 8.8 1.2e-58 198.9 8.8 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 ACL94466.1 - 1.4e-10 41.0 0.8 2.3e-10 40.3 0.8 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase FliP PF00813.20 ACL94467.1 - 1.4e-78 263.1 12.0 1.9e-78 262.7 12.0 1.1 1 0 0 1 1 1 1 FliP family PsbQ PF05757.11 ACL94467.1 - 0.43 10.3 1.6 2.8 7.6 0.8 2.0 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) MerC PF03203.14 ACL94467.1 - 0.51 10.8 16.1 0.08 13.4 7.8 2.9 2 1 0 2 2 2 0 MerC mercury resistance protein FliO PF04347.13 ACL94468.1 - 1.6e-08 34.7 0.0 2e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Flagellar biosynthesis protein, FliO Flg_bb_rod PF00460.20 ACL94469.1 - 0.00043 20.1 0.0 0.00092 19.1 0.0 1.6 1 0 0 1 1 1 1 Flagella basal body rod protein Flg_bbr_C PF06429.13 ACL94469.1 - 0.041 14.0 1.0 0.07 13.3 0.7 1.6 2 0 0 2 2 2 0 Flagellar basal body rod FlgEFG protein C-terminal Sin3_corepress PF08295.12 ACL94469.1 - 0.091 12.8 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Sin3 family co-repressor MIT PF04212.18 ACL94469.1 - 0.16 12.0 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Flg_bbr_C PF06429.13 ACL94470.1 - 2.3e-10 40.5 0.2 4.4e-10 39.5 0.2 1.6 1 0 0 1 1 1 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 ACL94470.1 - 1.1e-05 25.3 2.0 1.1e-05 25.3 2.0 2.2 2 0 0 2 2 2 1 Flagella basal body rod protein FliE PF02049.18 ACL94471.1 - 2.8e-21 75.4 0.4 3.4e-21 75.2 0.4 1.2 1 0 0 1 1 1 1 Flagellar hook-basal body complex protein FliE Ribosomal_L14 PF00238.19 ACL94471.1 - 0.0071 16.4 0.3 0.013 15.5 0.1 1.5 1 1 0 1 1 1 1 Ribosomal protein L14p/L23e Lipoprotein_Ltp PF07553.11 ACL94471.1 - 0.27 11.5 2.4 0.33 11.2 0.3 2.1 2 1 1 3 3 3 0 Host cell surface-exposed lipoprotein Urocanase_C PF17392.2 ACL94473.1 - 1.2e-91 305.5 0.2 2e-91 304.7 0.2 1.4 1 0 0 1 1 1 1 Urocanase C-terminal domain Urocanase PF01175.18 ACL94473.1 - 1.4e-86 289.5 0.0 1.9e-86 289.1 0.0 1.2 1 0 0 1 1 1 1 Urocanase Rossmann-like domain Urocanase_N PF17391.2 ACL94473.1 - 1.2e-60 202.8 0.0 2.3e-60 201.8 0.0 1.5 1 0 0 1 1 1 1 Urocanase N-terminal domain FGase PF05013.12 ACL94474.1 - 7.9e-70 235.4 0.0 1e-69 235.1 0.0 1.1 1 0 0 1 1 1 1 N-formylglutamate amidohydrolase TMEM206 PF15122.6 ACL94474.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 TMEM206 protein family Lyase_aromatic PF00221.19 ACL94475.1 - 2.8e-183 609.8 10.0 3.2e-183 609.6 10.0 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase Complex1_49kDa PF00346.19 ACL94475.1 - 0.23 10.5 0.0 0.52 9.4 0.0 1.5 1 1 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Amidohydro_3 PF07969.11 ACL94476.1 - 1.8e-19 70.6 12.4 1.9e-14 54.0 6.4 2.8 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 ACL94476.1 - 4.1e-16 59.2 4.6 2e-15 57.0 4.6 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 ACL94477.2 - 9e-34 117.3 0.0 1.1e-33 117.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family UTRA PF07702.13 ACL94478.1 - 7e-31 107.0 0.1 1e-30 106.4 0.1 1.2 1 0 0 1 1 1 1 UTRA domain GntR PF00392.21 ACL94478.1 - 6e-17 61.0 0.0 1.1e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 ACL94478.1 - 0.0014 18.6 0.3 0.0047 16.9 0.1 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain RP-C PF03428.13 ACL94478.1 - 0.0045 16.6 0.0 0.0081 15.8 0.0 1.3 1 0 0 1 1 1 1 Replication protein C N-terminal domain HTH_Crp_2 PF13545.6 ACL94478.1 - 0.0061 16.5 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR PF01047.22 ACL94478.1 - 0.037 14.0 0.0 0.07 13.1 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_41 PF14502.6 ACL94478.1 - 0.086 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain tRNA_edit PF04073.15 ACL94479.2 - 1.9e-24 86.1 0.1 2.4e-24 85.8 0.1 1.1 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain RepC PF06504.11 ACL94479.2 - 0.046 12.9 0.0 0.06 12.5 0.0 1.1 1 0 0 1 1 1 0 Replication protein C (RepC) Cu-oxidase_3 PF07732.15 ACL94480.3 - 3.2e-48 162.7 0.7 1.1e-39 135.2 0.3 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 ACL94480.3 - 2.1e-33 115.0 6.9 6.4e-28 97.2 1.7 3.4 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.22 ACL94480.3 - 7.9e-29 100.8 0.0 2.4e-24 86.2 0.0 3.0 4 1 0 4 4 4 2 Multicopper oxidase Cupredoxin_1 PF13473.6 ACL94480.3 - 1.7e-05 24.8 0.0 0.062 13.4 0.0 3.0 3 1 0 3 3 3 2 Cupredoxin-like domain TAT_signal PF10518.9 ACL94480.3 - 0.00054 19.7 2.8 0.0013 18.5 2.8 1.7 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence CopB PF05275.11 ACL94481.1 - 3.2e-61 206.5 3.3 5.6e-61 205.8 3.3 1.3 1 1 0 1 1 1 1 Copper resistance protein B precursor (CopB) AMP-binding PF00501.28 ACL94482.1 - 1.2e-104 350.3 0.0 1.5e-104 350.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ACL94482.1 - 8.4e-23 81.1 4.3 1.5e-22 80.4 0.7 2.6 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain GFO_IDH_MocA PF01408.22 ACL94483.1 - 3.1e-18 66.7 0.0 5.6e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 ACL94483.1 - 0.025 15.2 0.0 0.045 14.4 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain CoA_binding PF02629.19 ACL94483.1 - 0.034 14.8 0.0 0.075 13.7 0.0 1.6 1 0 0 1 1 1 0 CoA binding domain Glyco_hydro_3_C PF01915.22 ACL94484.1 - 1.4e-56 191.7 0.1 2.3e-56 191.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ACL94484.1 - 1.6e-45 155.9 0.1 3.2e-45 154.9 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ACL94484.1 - 3.3e-21 75.1 0.0 9.1e-21 73.7 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain NPCBM_assoc PF10633.9 ACL94484.1 - 0.0069 16.6 3.2 0.021 15.1 0.3 2.9 2 0 0 2 2 2 1 NPCBM-associated, NEW3 domain of alpha-galactosidase Peripla_BP_3 PF13377.6 ACL94485.1 - 3.5e-35 121.8 0.2 1.4e-34 119.8 0.1 2.0 2 1 1 3 3 3 1 Periplasmic binding protein-like domain LacI PF00356.21 ACL94485.1 - 6.3e-21 73.9 0.2 1.1e-20 73.1 0.2 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_1 PF00532.21 ACL94485.1 - 1.1e-15 57.8 0.0 1.9e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 ACL94485.1 - 2.7e-06 27.2 0.0 5.5e-06 26.2 0.0 1.5 2 0 0 2 2 2 1 Periplasmic binding protein domain HTH_Tnp_ISL3 PF13542.6 ACL94485.1 - 0.0005 19.4 0.0 0.0012 18.3 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_3 PF01381.22 ACL94485.1 - 0.0018 18.3 0.0 0.005 16.9 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix HTH_7 PF02796.15 ACL94485.1 - 0.012 15.6 0.0 0.028 14.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_31 PF13560.6 ACL94485.1 - 0.022 15.1 0.2 0.072 13.4 0.2 2.0 1 1 0 1 1 1 0 Helix-turn-helix domain MerR PF00376.23 ACL94485.1 - 0.025 14.3 0.0 0.069 12.9 0.0 1.8 1 0 0 1 1 1 0 MerR family regulatory protein TetR_N PF00440.23 ACL94485.1 - 0.029 14.2 0.0 0.078 12.8 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family MarR_2 PF12802.7 ACL94485.1 - 0.04 13.8 0.2 0.31 11.0 0.0 2.5 3 0 0 3 3 2 0 MarR family HTH_Crp_2 PF13545.6 ACL94485.1 - 0.045 13.7 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_24 PF13412.6 ACL94485.1 - 0.048 13.2 0.0 0.14 11.7 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_29 PF13551.6 ACL94485.1 - 0.053 13.6 0.1 1 9.4 0.0 2.4 1 1 1 2 2 2 0 Winged helix-turn helix HTH_38 PF13936.6 ACL94485.1 - 0.071 12.9 0.0 0.4 10.5 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 ACL94485.1 - 0.087 12.6 0.0 0.54 10.1 0.0 2.2 1 1 1 2 2 2 0 Homeodomain-like domain HTH_1 PF00126.27 ACL94485.1 - 0.14 12.2 0.0 2.5 8.1 0.0 2.7 1 1 1 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_17 PF12728.7 ACL94485.1 - 0.16 12.2 0.1 0.62 10.3 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain rRNA_methylase PF06962.12 ACL94485.1 - 0.24 11.4 0.0 0.43 10.6 0.0 1.4 1 0 0 1 1 1 0 Putative rRNA methylase TonB_dep_Rec PF00593.24 ACL94486.2 - 5.4e-34 118.9 27.7 5.4e-34 118.9 27.7 3.0 1 1 1 3 3 3 1 TonB dependent receptor Plug PF07715.15 ACL94486.2 - 2.4e-10 40.9 1.7 2.4e-10 40.9 1.7 2.9 3 1 1 4 4 4 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 ACL94486.2 - 2.5e-08 33.3 0.1 2.5e-08 33.3 0.1 3.3 3 2 0 3 3 3 1 Outer membrane protein beta-barrel family Trp_halogenase PF04820.14 ACL94487.1 - 6.3e-189 628.5 0.0 7.2e-189 628.3 0.0 1.0 1 0 0 1 1 1 1 Tryptophan halogenase DAO PF01266.24 ACL94487.1 - 1.1e-05 25.2 1.4 2.7e-05 23.9 1.4 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ACL94487.1 - 9.1e-05 22.5 1.2 0.0038 17.2 0.5 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 ACL94487.1 - 0.00063 19.1 0.1 0.0033 16.7 0.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ACL94487.1 - 0.0013 18.9 0.3 0.003 17.8 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 ACL94487.1 - 0.011 14.8 0.0 1 8.3 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.7 ACL94487.1 - 0.012 15.0 0.0 0.74 9.1 0.2 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 ACL94487.1 - 0.12 12.9 1.1 0.26 11.9 0.6 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ACL94487.1 - 0.17 10.6 0.1 0.24 10.1 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 ACL94488.1 - 2.2e-188 626.8 0.0 2.5e-188 626.6 0.0 1.0 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 ACL94488.1 - 3.9e-06 26.3 0.3 0.012 14.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ACL94488.1 - 1.3e-05 24.9 1.3 8.9e-05 22.2 1.3 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ACL94488.1 - 0.00042 19.5 0.2 0.027 13.5 0.0 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 ACL94488.1 - 0.0058 15.9 0.0 0.017 14.4 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 ACL94488.1 - 0.028 13.8 0.4 1 8.7 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 ACL94488.1 - 0.055 14.0 1.1 14 6.3 0.9 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ACL94488.1 - 0.32 10.0 2.2 15 4.5 1.6 2.3 2 1 0 2 2 2 0 Glucose inhibited division protein A Peptidase_M17 PF00883.21 ACL94493.2 - 5.6e-115 383.9 0.3 7.4e-115 383.5 0.3 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 ACL94493.2 - 1.1e-05 25.3 0.3 3.3e-05 23.8 0.3 1.9 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain PDZ PF00595.24 ACL94493.2 - 0.02 15.3 0.1 0.043 14.2 0.1 1.5 1 0 0 1 1 1 0 PDZ domain Bac_rhamnosid6H PF17389.2 ACL94494.1 - 9.8e-121 403.2 0.0 1.4e-120 402.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 ACL94494.1 - 1.4e-50 171.5 0.0 3.2e-50 170.3 0.0 1.7 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 ACL94494.1 - 4.4e-29 100.5 0.0 8.4e-29 99.6 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 ACL94494.1 - 3.7e-21 74.7 0.1 9.7e-21 73.4 0.0 1.8 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain Pro_isomerase PF00160.21 ACL94495.1 - 1.9e-31 109.5 0.0 2.2e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Sugar_tr PF00083.24 ACL94496.2 - 1.3e-35 123.2 26.1 2e-26 92.9 8.9 3.0 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 ACL94496.2 - 2.4e-28 99.1 44.7 2.5e-28 99.0 32.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 ACL94496.2 - 0.0057 15.6 15.6 0.0058 15.5 3.3 3.4 2 1 2 4 4 4 2 MFS_1 like family DUF2721 PF11026.8 ACL94496.2 - 0.19 11.6 0.1 0.19 11.6 0.1 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF2721) Sigma70_r2 PF04542.14 ACL94497.2 - 4.5e-15 55.2 0.1 8.6e-15 54.3 0.1 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 ACL94497.2 - 4.9e-15 54.9 0.1 9.3e-15 54.0 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 ACL94497.2 - 5.2e-07 29.7 0.0 1e-06 28.8 0.0 1.5 1 1 0 1 1 1 1 ECF sigma factor Sigma70_r4 PF04545.16 ACL94497.2 - 5.3e-07 29.1 0.0 1.1e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_40 PF14493.6 ACL94497.2 - 0.00038 20.9 0.0 0.0022 18.4 0.0 2.1 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_17 PF12728.7 ACL94497.2 - 0.0015 18.7 0.2 0.005 17.0 0.1 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.6 ACL94497.2 - 0.0073 15.8 0.0 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_38 PF13936.6 ACL94497.2 - 0.022 14.5 0.1 0.2 11.5 0.0 2.5 1 1 1 2 2 2 0 Helix-turn-helix domain DprA_WH PF17782.1 ACL94497.2 - 0.068 13.3 0.0 0.17 12.0 0.0 1.8 1 1 0 1 1 1 0 DprA winged helix domain FecR PF04773.13 ACL94498.1 - 7.2e-15 55.4 2.4 1.1e-14 54.8 1.8 1.6 2 0 0 2 2 2 1 FecR protein DUF4880 PF16220.5 ACL94498.1 - 7.4e-11 41.8 14.5 7.4e-11 41.8 14.5 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF4880) TonB_dep_Rec PF00593.24 ACL94499.2 - 5.1e-36 125.6 32.8 5.1e-36 125.6 32.8 2.1 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 ACL94499.2 - 7.3e-13 49.0 2.6 7.3e-13 49.0 2.6 2.9 3 0 0 3 3 3 1 TonB-dependent Receptor Plug Domain G_glu_transpept PF01019.21 ACL94500.1 - 3.5e-181 603.4 1.1 4.1e-181 603.2 1.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Peptidase_M14 PF00246.24 ACL94501.1 - 2.5e-51 175.2 0.1 3.2e-51 174.9 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase FCD PF07729.12 ACL94502.2 - 1.2e-23 83.9 8.3 1.2e-23 83.9 8.3 2.3 3 0 0 3 3 3 1 FCD domain GntR PF00392.21 ACL94502.2 - 2.7e-23 81.4 0.1 6.1e-23 80.2 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family TrmB PF01978.19 ACL94502.2 - 0.00056 19.7 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Fe_dep_repress PF01325.19 ACL94502.2 - 0.0023 18.1 0.0 0.0054 16.9 0.0 1.7 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain Rrf2 PF02082.20 ACL94502.2 - 0.0044 17.3 0.0 0.01 16.1 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator HTH_Crp_2 PF13545.6 ACL94502.2 - 0.0078 16.2 0.3 0.029 14.4 0.0 2.1 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_IclR PF09339.10 ACL94502.2 - 0.0082 15.9 0.5 0.58 10.0 0.0 3.0 2 0 0 2 2 2 1 IclR helix-turn-helix domain 2_5_RNA_ligase2 PF13563.6 ACL94502.2 - 0.011 15.6 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily MarR PF01047.22 ACL94502.2 - 0.025 14.5 0.0 1.4 8.9 0.0 2.5 2 0 0 2 2 2 0 MarR family HTH_41 PF14502.6 ACL94502.2 - 0.033 13.9 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_DeoR PF08220.12 ACL94502.2 - 0.06 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 ACL94502.2 - 0.11 12.5 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 HTH domain Glyoxalase PF00903.25 ACL94503.2 - 2e-05 24.8 0.0 0.00011 22.5 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TPR_8 PF13181.6 ACL94503.2 - 0.097 12.9 0.1 1.4 9.4 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyoxalase_6 PF18029.1 ACL94503.2 - 0.13 13.0 0.0 0.19 12.5 0.0 1.3 1 1 0 1 1 1 0 Glyoxalase-like domain MFS_1 PF07690.16 ACL94504.1 - 1.5e-54 185.3 65.4 1e-48 166.1 42.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4027 PF13219.6 ACL94504.1 - 0.1 12.5 0.2 0.37 10.7 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) Glyco_hydro_43 PF04616.14 ACL94505.1 - 3.8e-108 361.2 0.0 9e-108 360.0 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 ACL94505.1 - 2.7e-61 206.8 0.0 3.8e-61 206.4 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain TonB_dep_Rec PF00593.24 ACL94507.1 - 3.8e-28 99.6 37.9 3.8e-28 99.6 37.9 2.3 1 1 0 2 2 2 1 TonB dependent receptor Plug PF07715.15 ACL94507.1 - 4.4e-16 59.4 2.4 1.5e-15 57.7 2.4 2.0 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain TetR_N PF00440.23 ACL94509.1 - 9.6e-13 47.7 1.3 2.3e-12 46.5 1.3 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 ACL94509.1 - 2.5e-11 43.8 0.0 5.1e-11 42.9 0.0 1.6 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_9 PF14514.6 ACL94509.1 - 0.038 14.1 0.0 0.1 12.8 0.0 1.7 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TetR_C_10 PF16295.5 ACL94509.1 - 0.085 13.2 0.0 0.22 11.8 0.0 1.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain YjbR PF04237.13 ACL94510.1 - 1.4e-13 51.2 0.1 1.6e-13 51.0 0.1 1.1 1 0 0 1 1 1 1 YjbR DUF5519 PF17648.1 ACL94510.1 - 0.043 13.7 0.1 0.056 13.3 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5519) PMSR PF01625.21 ACL94511.1 - 2.1e-67 226.1 0.3 2.5e-67 225.8 0.3 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase TonB_dep_Rec PF00593.24 ACL94512.1 - 1.3e-23 84.7 69.0 2.3e-23 83.8 50.3 2.7 1 1 2 3 3 3 2 TonB dependent receptor OMP_b-brl_3 PF14905.6 ACL94512.1 - 3.2e-15 56.0 2.8 3.2e-15 56.0 2.8 3.3 3 1 1 4 4 4 1 Outer membrane protein beta-barrel family Plug PF07715.15 ACL94512.1 - 3.9e-10 40.2 0.2 1.4e-09 38.5 0.2 1.9 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain ABC_tran PF00005.27 ACL94515.1 - 1.9e-47 161.2 0.1 2.2e-23 83.3 0.0 3.1 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 ACL94515.1 - 6.8e-24 83.7 9.8 6.3e-23 80.6 6.6 2.3 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 ACL94515.1 - 2.7e-13 50.4 2.5 0.0057 16.5 0.0 4.3 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ACL94515.1 - 3.2e-08 34.3 1.3 0.0066 17.0 0.1 3.2 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.19 ACL94515.1 - 8.2e-08 31.9 0.4 0.23 10.9 0.0 4.2 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ACL94515.1 - 5.5e-06 26.0 0.0 0.08 12.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ACL94515.1 - 1.5e-05 24.9 0.1 0.15 12.0 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 ACL94515.1 - 5.6e-05 23.2 0.1 0.066 13.3 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 ACL94515.1 - 0.00017 22.0 0.4 0.81 10.0 0.0 2.7 3 0 0 3 3 2 2 AAA ATPase domain ATP-synt_ab PF00006.25 ACL94515.1 - 0.00025 20.8 0.0 0.014 15.1 0.1 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.29 ACL94515.1 - 0.00034 21.0 0.1 0.69 10.3 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 ACL94515.1 - 0.00062 20.0 0.6 1.3 9.2 0.0 2.9 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 ACL94515.1 - 0.00098 19.4 0.3 0.67 10.2 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 ACL94515.1 - 0.00098 19.3 0.4 0.63 10.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 ACL94515.1 - 0.0012 18.6 0.2 0.25 11.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 ACL94515.1 - 0.0013 18.0 7.0 0.17 11.1 0.1 2.7 3 0 0 3 3 2 2 Zeta toxin cobW PF02492.19 ACL94515.1 - 0.0025 17.4 0.1 0.22 11.1 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 ACL94515.1 - 0.0027 18.0 0.8 2.2 8.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_27 PF13514.6 ACL94515.1 - 0.0061 16.2 0.0 2.7 7.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 ACL94515.1 - 0.011 15.3 0.1 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Arf PF00025.21 ACL94515.1 - 0.018 14.5 0.1 6.8 6.1 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family NACHT PF05729.12 ACL94515.1 - 0.026 14.4 2.3 3.6 7.5 0.1 2.6 3 0 0 3 3 2 0 NACHT domain AAA_18 PF13238.6 ACL94515.1 - 0.03 14.9 0.1 12 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 ACL94515.1 - 0.031 13.5 0.5 1.4 8.0 0.2 2.2 2 0 0 2 2 2 0 NB-ARC domain TsaE PF02367.17 ACL94515.1 - 0.033 14.2 0.1 0.77 9.8 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 ACL94515.1 - 0.049 13.7 0.0 11 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ACL94515.1 - 0.051 13.1 0.2 14 5.1 0.1 2.8 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 ACL94515.1 - 0.058 13.3 0.1 7.6 6.4 0.0 2.6 2 0 0 2 2 2 0 NTPase FeoB_N PF02421.18 ACL94515.1 - 0.061 12.8 0.2 0.71 9.4 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_13 PF13166.6 ACL94515.1 - 0.069 11.8 4.0 1.1 7.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 ACL94515.1 - 0.091 12.8 2.6 0.98 9.5 0.0 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain PduV-EutP PF10662.9 ACL94515.1 - 0.12 12.2 0.2 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.17 ACL94515.1 - 0.14 11.9 1.0 9 6.0 0.0 2.7 3 0 0 3 3 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 ACL94515.1 - 0.16 11.7 7.1 3.7 7.2 1.1 3.5 4 1 0 4 4 3 0 AAA domain PRK PF00485.18 ACL94515.1 - 0.25 11.0 2.2 6.4 6.5 0.0 2.9 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family AAA_15 PF13175.6 ACL94515.1 - 0.64 9.7 3.1 9.4 5.8 0.0 2.7 4 0 0 4 4 2 0 AAA ATPase domain DUF3584 PF12128.8 ACL94515.1 - 2.4 5.5 13.9 0.54 7.7 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) TonB_dep_Rec PF00593.24 ACL94516.1 - 1.5e-60 206.4 34.1 1.5e-60 206.4 34.1 3.2 2 2 0 2 2 2 1 TonB dependent receptor Plug PF07715.15 ACL94516.1 - 1.3e-15 57.9 3.4 1.3e-15 57.9 3.4 3.1 3 0 0 3 3 3 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 ACL94516.1 - 2.9e-11 43.0 8.4 7e-11 41.7 0.7 3.5 3 1 0 3 3 3 2 Outer membrane protein beta-barrel family SapC PF07277.11 ACL94517.1 - 2.1e-66 223.7 0.0 2.4e-66 223.5 0.0 1.0 1 0 0 1 1 1 1 SapC Cupin_8 PF13621.6 ACL94518.1 - 3.7e-60 203.8 0.0 4.6e-60 203.5 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain ADC PF06314.11 ACL94518.1 - 0.025 14.1 0.1 0.04 13.5 0.1 1.2 1 0 0 1 1 1 0 Acetoacetate decarboxylase (ADC) Cupin_4 PF08007.12 ACL94518.1 - 0.034 13.6 0.0 0.059 12.8 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein Trp_halogenase PF04820.14 ACL94519.1 - 8.7e-197 654.5 0.0 1e-196 654.2 0.0 1.0 1 0 0 1 1 1 1 Tryptophan halogenase FAD_oxidored PF12831.7 ACL94519.1 - 0.0001 21.8 0.2 0.25 10.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ACL94519.1 - 0.00094 18.5 0.2 0.038 13.2 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ACL94519.1 - 0.0014 18.3 5.1 0.013 15.1 5.1 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ACL94519.1 - 0.0038 17.2 0.3 0.2 11.6 0.2 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 ACL94519.1 - 0.16 12.6 0.6 0.42 11.2 0.6 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glycos_transf_1 PF00534.20 ACL94520.1 - 1.6e-08 34.3 0.0 2.3e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ACL94520.1 - 1.2e-07 32.2 0.1 3.1e-07 30.9 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ACL94520.1 - 9e-05 22.5 1.3 0.00024 21.2 1.2 1.7 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 ACL94520.1 - 0.036 14.4 0.0 0.095 13.1 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 NAD_binding_10 PF13460.6 ACL94520.1 - 0.037 13.9 0.0 0.085 12.7 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H-binding Glyco_trans_4_4 PF13579.6 ACL94520.1 - 0.82 10.1 12.2 0.056 13.9 6.0 2.3 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain Methyltransf_21 PF05050.12 ACL94521.2 - 3.2e-18 66.3 0.0 4.7e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain V_cholerae_RfbT PF05575.11 ACL94521.2 - 1.2e-08 34.6 0.0 1.8e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Vibrio cholerae RfbT protein tRNA_bind PF01588.20 ACL94521.2 - 0.13 12.4 0.1 0.26 11.4 0.1 1.4 1 0 0 1 1 1 0 Putative tRNA binding domain RskA PF10099.9 ACL94521.2 - 3.9 7.7 9.0 7.9 6.7 9.0 1.5 1 0 0 1 1 1 0 Anti-sigma-K factor rskA HTH_19 PF12844.7 ACL94523.1 - 8.4e-11 41.7 0.0 1e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 ACL94523.1 - 1.2e-09 38.1 0.0 1.9e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 ACL94523.1 - 1.9e-08 34.6 1.0 2.7e-08 34.0 0.6 1.6 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.6 ACL94523.1 - 0.028 14.0 0.0 0.063 12.8 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_29 PF13551.6 ACL94523.1 - 0.039 14.0 0.2 4.5 7.4 0.0 2.7 1 1 2 3 3 3 0 Winged helix-turn helix HTH_25 PF13413.6 ACL94523.1 - 0.054 13.3 0.8 0.4 10.6 0.8 2.2 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 ACL94523.1 - 0.055 13.3 0.1 4 7.3 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain HTH_37 PF13744.6 ACL94523.1 - 0.13 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HemolysinCabind PF00353.19 ACL94524.2 - 5.9e-07 29.4 42.4 0.0027 17.7 5.5 7.9 6 1 1 7 7 7 5 RTX calcium-binding nonapeptide repeat (4 copies) DUF3491 PF11996.8 ACL94524.2 - 1.2 6.8 3.1 2.2 6.0 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3491) ABC_tran PF00005.27 ACL94525.1 - 3.9e-29 101.9 0.0 5.8e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ACL94525.1 - 8.2e-08 32.4 0.0 0.0022 17.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_membrane PF00664.23 ACL94525.1 - 8.4e-08 32.2 7.2 1.8e-07 31.1 7.2 1.5 1 1 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 ACL94525.1 - 0.00035 20.1 0.0 0.0012 18.3 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ACL94525.1 - 0.029 14.1 0.0 0.094 12.5 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 ACL94525.1 - 0.091 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 ACL94525.1 - 0.13 12.4 0.0 1 9.5 0.0 2.3 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ACL94525.1 - 0.16 12.1 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase HlyD_3 PF13437.6 ACL94526.1 - 2.1e-12 47.7 1.4 8e-09 36.2 0.1 3.0 2 2 1 3 3 3 2 HlyD family secretion protein HlyD_D23 PF16576.5 ACL94526.1 - 4e-09 36.0 4.7 2.1e-05 23.8 0.4 2.3 2 0 0 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 ACL94526.1 - 1e-07 31.7 0.0 5.8e-07 29.2 0.0 2.3 1 0 0 1 1 1 1 Biotin-lipoyl like HlyD PF00529.20 ACL94526.1 - 0.00024 20.9 0.0 0.00063 19.6 0.0 1.7 2 1 0 2 2 2 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl PF00364.22 ACL94526.1 - 0.0011 18.8 0.1 0.018 14.8 0.1 2.4 2 0 0 2 2 2 1 Biotin-requiring enzyme PTS_EIIA_1 PF00358.20 ACL94526.1 - 0.024 14.4 0.1 0.23 11.2 0.0 2.3 2 0 0 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Peptidase_M23 PF01551.22 ACL94526.1 - 0.053 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M23 NQRA PF05896.11 ACL94526.1 - 0.057 12.8 0.2 0.27 10.6 0.0 1.9 2 0 0 2 2 2 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) CEP63 PF17045.5 ACL94526.1 - 0.067 13.1 4.0 0.1 12.5 4.0 1.2 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa RnfC_N PF13375.6 ACL94526.1 - 0.13 12.2 1.2 0.89 9.6 0.1 2.7 3 0 0 3 3 3 0 RnfC Barrel sandwich hybrid domain DUF1664 PF07889.12 ACL94526.1 - 0.69 10.0 3.9 1.3 9.1 0.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) KfrA_N PF11740.8 ACL94526.1 - 9.3 7.0 10.3 0.32 11.7 3.5 2.0 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term GDP_Man_Dehyd PF16363.5 ACL94527.1 - 9.8e-128 426.2 0.0 1.2e-127 426.0 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ACL94527.1 - 1.2e-63 214.8 0.0 1.5e-63 214.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ACL94527.1 - 0.00014 21.1 0.0 0.00019 20.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 ACL94527.1 - 0.062 12.4 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 ACL94527.1 - 0.11 12.4 0.0 0.31 10.9 0.0 1.9 2 0 0 2 2 2 0 NAD(P)H-binding PglD_N PF17836.1 ACL94528.1 - 1.3e-14 54.6 0.6 3.8e-14 53.1 0.0 1.9 2 0 0 2 2 2 1 PglD N-terminal domain Hexapep PF00132.24 ACL94528.1 - 9.6e-10 37.8 28.5 0.00024 20.7 4.3 4.6 2 1 4 6 6 6 5 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 ACL94528.1 - 4.3e-05 23.2 10.5 0.00061 19.5 5.1 4.9 5 1 0 5 5 5 2 Hexapeptide repeat of succinyl-transferase DegT_DnrJ_EryC1 PF01041.17 ACL94529.1 - 3.7e-132 441.0 0.0 4.2e-132 440.8 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 ACL94529.1 - 4.6e-12 45.8 0.0 7.6e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 ACL94529.1 - 2.3e-06 26.4 0.0 3.2e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 ACL94529.1 - 1.1e-05 24.9 0.1 1.9e-05 24.1 0.1 1.3 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 ACL94529.1 - 1.4e-05 24.3 0.0 2.1e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Glycos_transf_1 PF00534.20 ACL94530.1 - 3.5e-18 65.7 0.0 5.1e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ACL94530.1 - 2.8e-13 50.5 0.0 4.4e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ACL94530.1 - 0.00031 20.8 0.9 0.0035 17.4 0.9 2.7 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 ACL94530.1 - 0.003 18.0 0.9 0.04 14.4 0.5 2.7 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 ACL94530.1 - 0.0035 17.7 0.0 0.012 16.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 ACL94531.1 - 1.2e-20 73.7 0.0 1.9e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ACL94531.1 - 9e-14 52.1 0.0 1.9e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 ACL94531.1 - 6.6e-05 23.2 0.0 0.00013 22.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ACL94531.1 - 0.053 13.5 0.4 2.1 8.3 0.0 2.4 1 1 1 2 2 2 0 Glycosyltransferase Family 4 OEP PF02321.18 ACL94532.1 - 1.4e-42 145.7 39.8 2.3e-21 76.4 10.7 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein DUF4041 PF13250.6 ACL94532.1 - 0.16 11.9 0.2 5.9 6.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) Glycos_transf_1 PF00534.20 ACL94533.2 - 1.2e-07 31.4 0.0 2.3e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ACL94533.2 - 2.1e-05 25.0 0.0 4.4e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 TPR_14 PF13428.6 ACL94533.2 - 9.1 7.4 13.8 7.4 7.7 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat MethyTransf_Reg PF10119.9 ACL94534.2 - 6.4e-32 110.1 1.8 1.6e-31 108.8 0.8 2.3 3 0 0 3 3 3 1 Predicted methyltransferase regulatory domain Methyltransf_11 PF08241.12 ACL94534.2 - 1.9e-05 25.2 0.0 0.00028 21.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ACL94534.2 - 0.00012 22.7 0.0 0.00029 21.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ACL94534.2 - 0.00021 21.1 0.0 0.00046 20.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ACL94534.2 - 0.0056 17.4 0.0 0.013 16.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF599 PF04654.12 ACL94535.1 - 2.2e-45 154.7 8.8 2.5e-45 154.5 8.8 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF599 Sugar_tr PF00083.24 ACL94536.1 - 1.1e-36 126.7 31.2 3.7e-35 121.7 31.2 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ACL94536.1 - 1.5e-33 116.2 77.3 4.6e-24 85.0 51.0 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1129 PF06570.11 ACL94536.1 - 0.015 14.8 1.8 0.015 14.8 1.8 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) DUF3309 PF11752.8 ACL94537.1 - 2.4e-24 85.1 16.5 2.6e-24 85.0 16.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3309) MerC PF03203.14 ACL94537.1 - 0.16 12.5 4.4 0.17 12.3 4.4 1.1 1 0 0 1 1 1 0 MerC mercury resistance protein FeoB_associated PF12669.7 ACL94537.1 - 0.79 10.2 6.8 0.97 9.9 0.1 2.1 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein DUF2207 PF09972.9 ACL94537.1 - 8.2 5.1 8.4 8.3 5.0 8.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF983 PF06170.12 ACL94538.1 - 1.1e-27 96.2 1.8 1.1e-27 96.2 1.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF983) TF_Zn_Ribbon PF08271.12 ACL94538.1 - 0.00095 18.6 0.2 0.0013 18.2 0.2 1.2 1 0 0 1 1 1 1 TFIIB zinc-binding DUF1610 PF07754.11 ACL94538.1 - 0.0072 16.3 0.7 0.036 14.0 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1610) DUF1272 PF06906.11 ACL94538.1 - 0.026 14.6 2.3 0.75 9.9 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) Zn-ribbon_8 PF09723.10 ACL94538.1 - 0.047 13.8 0.2 6.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_2 PF13240.6 ACL94538.1 - 0.067 12.9 4.4 3 7.7 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_10 PF10058.9 ACL94538.1 - 0.073 12.8 0.0 5.7 6.8 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-RING_7 PF02591.15 ACL94538.1 - 0.23 11.7 2.7 1.7 8.9 0.1 2.3 2 0 0 2 2 2 0 C4-type zinc ribbon domain Nudix_N_2 PF14803.6 ACL94538.1 - 0.28 11.1 4.6 7.3 6.6 1.1 2.2 2 0 0 2 2 2 0 Nudix N-terminal zf-C4_Topoisom PF01396.19 ACL94538.1 - 0.29 11.0 2.0 2.7 7.8 0.1 2.1 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Zn_Tnp_IS1595 PF12760.7 ACL94538.1 - 0.38 10.8 4.1 25 4.9 5.6 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain ADK_lid PF05191.14 ACL94538.1 - 0.4 10.7 3.4 0.86 9.6 3.4 1.5 1 1 0 1 1 1 0 Adenylate kinase, active site lid zf-ribbon_3 PF13248.6 ACL94538.1 - 0.52 9.8 4.7 4.7 6.7 1.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-LITAF-like PF10601.9 ACL94538.1 - 1.9 8.8 5.1 6.5 7.1 0.0 2.8 3 1 0 3 3 3 0 LITAF-like zinc ribbon domain Rubredoxin_2 PF18073.1 ACL94538.1 - 6.3 6.6 6.5 22 4.9 0.3 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain Entericidin PF08085.11 ACL94539.1 - 3.1e-08 33.4 3.1 4.1e-08 33.0 3.1 1.2 1 0 0 1 1 1 1 Entericidin EcnA/B family LPAM_1 PF08139.12 ACL94539.1 - 0.074 13.6 3.4 0.45 11.1 3.4 2.1 1 1 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Crystall PF00030.19 ACL94540.1 - 1.4e-17 63.6 0.0 2.1e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Beta/Gamma crystallin Trp_oprn_chp PF09534.10 ACL94540.1 - 0.074 12.9 0.0 0.091 12.6 0.0 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Crystall PF00030.19 ACL94541.1 - 9.9e-18 64.1 0.0 1.7e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Beta/Gamma crystallin CVNH PF08881.10 ACL94541.1 - 5.5e-05 23.8 0.0 7.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 CVNH domain Inhibitor_I36 PF03995.13 ACL94541.1 - 6.5e-05 22.8 0.0 0.00055 19.8 0.0 2.5 1 1 1 2 2 2 2 Peptidase inhibitor family I36 Penicil_amidase PF01804.18 ACL94542.1 - 1.3e-108 364.8 12.5 2.7e-108 363.8 12.5 1.5 1 1 0 1 1 1 1 Penicillin amidase Methyltransf_11 PF08241.12 ACL94543.2 - 0.00069 20.2 0.0 0.0029 18.2 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ACL94543.2 - 0.004 17.8 0.0 0.013 16.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 ACL94543.2 - 0.0042 16.5 0.0 0.0061 15.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Big_5 PF13205.6 ACL94545.1 - 0.0066 17.1 0.0 0.01 16.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial Ig-like domain DUF3883 PF13020.6 ACL94546.1 - 0.00013 21.9 0.0 0.0002 21.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) HATPase_c_3 PF13589.6 ACL94548.1 - 1.5e-19 70.2 0.0 2.3e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 ACL94548.1 - 0.0066 16.9 0.0 0.024 15.1 0.0 2.0 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_methylase PF00145.17 ACL94550.1 - 2.2e-49 168.6 0.0 1.1e-47 163.1 0.0 2.0 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase Plectin PF00681.20 ACL94550.1 - 0.027 14.3 0.0 2.3 8.2 0.0 2.4 2 0 0 2 2 2 0 Plectin repeat GTP_EFTU PF00009.27 ACL94551.1 - 9.1e-51 172.2 0.5 1.4e-50 171.5 0.5 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 ACL94551.1 - 1.6e-50 169.8 0.5 2.8e-50 169.0 0.5 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 ACL94551.1 - 1.4e-19 69.9 0.0 3.6e-19 68.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ACL94551.1 - 3.7e-11 43.3 1.0 1.2e-10 41.6 0.7 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ACL94551.1 - 9.9e-06 25.6 0.1 2e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 ACL94551.1 - 1.7e-05 24.5 0.0 3.6e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Ras family EFG_II PF14492.6 ACL94551.1 - 0.00054 20.0 0.0 0.0029 17.7 0.0 2.1 1 1 0 1 1 1 1 Elongation Factor G, domain II Roc PF08477.13 ACL94551.1 - 0.046 13.9 0.0 0.15 12.3 0.0 1.8 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 ACL94551.1 - 0.055 12.9 0.0 0.2 11.1 0.0 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF1134 PF06577.12 ACL94552.2 - 2.9e-68 228.7 0.7 3.5e-68 228.4 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1134) Mito_fiss_reg PF05308.11 ACL94552.2 - 0.41 10.7 2.7 0.54 10.3 2.7 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator UPF0114 PF03350.16 ACL94553.1 - 3e-36 124.2 2.7 3e-36 124.2 2.7 1.8 2 0 0 2 2 2 1 Uncharacterized protein family, UPF0114 DUF3169 PF11368.8 ACL94553.1 - 0.071 12.6 3.2 0.11 12.0 2.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3169) COX7a PF02238.15 ACL94553.1 - 0.43 11.0 1.6 4 7.9 1.7 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase subunit VII PHO4 PF01384.20 ACL94553.1 - 8.9 5.3 10.6 2.9 6.8 2.1 2.1 1 1 0 2 2 2 0 Phosphate transporter family DUF4139 PF13598.6 ACL94554.1 - 6.3e-06 26.1 0.0 4.1e-05 23.4 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4139) FixG_C PF11614.8 ACL94554.1 - 0.03 14.5 0.0 0.094 12.9 0.0 1.8 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase DUF4140 PF13600.6 ACL94554.1 - 0.052 14.0 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Phage_tail_3 PF08813.11 ACL94554.1 - 0.077 12.6 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Phage tail tube protein, TTP DUF4150 PF13665.6 ACL94554.1 - 0.14 12.3 1.3 0.27 11.4 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4150) CAP_N PF01213.19 ACL94554.1 - 0.21 11.0 0.9 0.31 10.5 0.9 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 ACL94554.1 - 4.7 7.3 5.8 9 6.4 5.8 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF4139 PF13598.6 ACL94555.1 - 2.9e-06 27.2 0.0 1.8e-05 24.6 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 ACL94555.1 - 4.9e-05 23.7 0.1 0.00063 20.1 0.1 2.3 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) PMSR PF01625.21 ACL94556.1 - 7.7e-51 172.3 0.0 9.2e-51 172.0 0.0 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Vsr PF03852.15 ACL94556.1 - 0.048 13.5 0.0 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 DNA mismatch endonuclease Vsr ACT_5 PF13710.6 ACL94557.3 - 0.014 15.2 0.0 0.026 14.4 0.0 1.5 2 0 0 2 2 2 0 ACT domain Col_cuticle_N PF01484.17 ACL94559.2 - 0.0048 16.9 0.4 0.0065 16.5 0.2 1.3 1 1 0 1 1 1 1 Nematode cuticle collagen N-terminal domain B3_4 PF03483.17 ACL94560.1 - 1.1e-56 191.3 0.0 1.5e-56 190.8 0.0 1.2 1 0 0 1 1 1 1 B3/4 domain tRNA_synthFbeta PF17759.1 ACL94560.1 - 9.6e-48 162.4 0.0 1.5e-47 161.8 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA_bind PF01588.20 ACL94560.1 - 2.5e-20 72.4 0.0 4.8e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain FDX-ACB PF03147.14 ACL94560.1 - 1.3e-19 70.4 0.0 2.2e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain B5 PF03484.15 ACL94560.1 - 5.4e-15 55.4 0.0 1.3e-14 54.2 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetase B5 domain tRNA-synt_2d PF01409.20 ACL94561.1 - 3.2e-104 347.7 0.0 3.9e-104 347.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) Phe_tRNA-synt_N PF02912.18 ACL94561.1 - 8e-23 80.2 1.2 1.2e-22 79.6 1.2 1.3 1 0 0 1 1 1 1 Aminoacyl tRNA synthetase class II, N-terminal domain Ribosomal_L20 PF00453.18 ACL94562.1 - 1.3e-46 157.1 2.6 1.5e-46 156.9 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L20 Ribosomal_L35p PF01632.19 ACL94563.1 - 1.1e-19 70.7 5.8 1.2e-19 70.6 5.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L35 MFS_1 PF07690.16 ACL94564.1 - 6e-63 212.9 68.6 1.2e-52 179.0 43.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ACL94564.1 - 7.2e-17 61.1 19.9 1.8e-09 36.7 3.2 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 ACL94564.1 - 2.9e-15 56.0 16.8 2.5e-07 29.9 0.6 3.0 1 1 2 3 3 3 3 MFS_1 like family Sugar_tr PF00083.24 ACL94564.1 - 4e-14 52.3 7.1 4e-14 52.3 7.1 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 ACL94564.1 - 2e-07 30.6 10.2 2e-07 30.6 10.2 2.2 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 ACL94564.1 - 8e-05 21.2 2.7 8e-05 21.2 2.7 2.5 1 1 2 3 3 3 1 Transmembrane secretion effector EutK_C PF16365.5 ACL94564.1 - 0.0046 17.0 0.9 0.37 10.8 0.1 2.6 1 1 1 2 2 2 2 Ethanolamine utilization protein EutK C-terminus OATP PF03137.20 ACL94564.1 - 3.2 5.9 7.6 0.17 10.2 0.9 2.2 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_S9 PF00326.21 ACL94565.1 - 7e-43 146.6 0.0 3.6e-42 144.2 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 ACL94565.1 - 6.9e-10 39.0 0.2 6.3e-07 29.2 0.2 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 ACL94565.1 - 4.5e-09 36.3 0.0 7.9e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 ACL94565.1 - 1.2e-08 34.9 0.2 0.00031 20.5 0.3 2.7 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 ACL94565.1 - 3.5e-08 33.3 0.4 2.5e-07 30.5 0.4 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 ACL94565.1 - 4.3e-08 33.2 0.0 0.00077 19.3 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 ACL94565.1 - 5.6e-07 29.1 0.1 0.0052 16.1 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 AXE1 PF05448.12 ACL94565.1 - 1.2e-05 24.2 0.0 0.0011 17.7 0.0 2.3 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 ACL94565.1 - 1.8e-05 24.7 0.1 4.3e-05 23.5 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ACL94565.1 - 2.6e-05 24.9 8.4 2.9e-05 24.8 3.6 3.1 3 2 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 ACL94565.1 - 0.0015 18.6 0.0 0.0053 16.9 0.0 1.9 2 0 0 2 2 1 1 TAP-like protein Esterase_phd PF10503.9 ACL94565.1 - 0.0033 17.0 0.1 0.012 15.1 0.1 1.8 1 1 0 1 1 1 1 Esterase PHB depolymerase LIP PF03583.14 ACL94565.1 - 0.0045 16.4 0.6 0.55 9.5 0.6 2.3 2 0 0 2 2 2 1 Secretory lipase BAAT_C PF08840.11 ACL94565.1 - 0.0062 16.5 0.0 0.082 12.8 0.0 2.1 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 ACL94565.1 - 0.007 16.0 0.0 0.02 14.6 0.0 1.8 2 0 0 2 2 2 1 Serine hydrolase (FSH1) DUF2920 PF11144.8 ACL94565.1 - 0.13 11.4 0.0 0.79 8.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) IF3_C PF00707.22 ACL94566.1 - 2.8e-39 133.0 1.3 4.3e-39 132.4 1.3 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 ACL94566.1 - 5e-28 97.2 0.1 8.6e-28 96.4 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain YitT_membrane PF02588.15 ACL94567.1 - 1e-32 113.2 16.6 1.3e-32 112.9 16.6 1.0 1 0 0 1 1 1 1 Uncharacterised 5xTM membrane BCR, YitT family COG1284 Glyco_transf_9 PF01075.17 ACL94568.1 - 3e-27 95.5 0.0 2.3e-26 92.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) Herpes_LP PF03363.13 ACL94568.1 - 0.066 13.0 0.2 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 Herpesvirus leader protein Glycos_transf_1 PF00534.20 ACL94569.1 - 4.3e-30 104.5 0.0 8.1e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ACL94569.1 - 1e-29 103.7 2.0 2.1e-29 102.7 2.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 ACL94569.1 - 1.2e-25 90.4 1.0 7.1e-25 88.0 0.2 2.3 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 ACL94569.1 - 1.1e-15 58.4 6.7 1.1e-15 58.4 6.7 2.5 3 0 0 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 ACL94569.1 - 1.6e-05 25.0 0.0 2.8e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Hydrolase_4 PF12146.8 ACL94570.1 - 3.7e-15 55.8 0.0 1.4e-11 44.1 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ACL94570.1 - 3.8e-13 49.7 0.1 3.2e-12 46.6 0.1 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ACL94570.1 - 7.2e-12 46.4 7.7 2.2e-11 44.8 7.6 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ACL94570.1 - 9.2e-06 25.3 0.0 5.3e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 ACL94570.1 - 0.0019 17.9 0.0 0.006 16.3 0.0 1.8 2 1 0 2 2 2 1 Putative esterase Abhydrolase_3 PF07859.13 ACL94570.1 - 0.0053 16.6 0.0 0.01 15.7 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Patatin PF01734.22 ACL94570.1 - 0.0066 16.6 0.2 0.0087 16.3 0.2 1.4 1 1 0 1 1 1 1 Patatin-like phospholipase DUF2048 PF09752.9 ACL94570.1 - 0.0076 15.4 0.2 0.037 13.1 0.0 1.9 2 0 0 2 2 2 1 Abhydrolase domain containing 18 Ser_hydrolase PF06821.13 ACL94570.1 - 0.008 16.1 0.0 0.021 14.7 0.0 1.6 2 0 0 2 2 2 1 Serine hydrolase DUF2920 PF11144.8 ACL94570.1 - 0.0097 15.1 0.0 0.014 14.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Peptidase_S15 PF02129.18 ACL94570.1 - 0.013 15.1 0.0 0.038 13.6 0.0 1.7 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) UPF0227 PF05728.12 ACL94570.1 - 0.018 15.0 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DLH PF01738.18 ACL94570.1 - 0.12 11.9 0.0 8.1 5.9 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Ndr PF03096.14 ACL94570.1 - 0.14 10.8 0.0 0.2 10.3 0.0 1.1 1 0 0 1 1 1 0 Ndr family RHH_1 PF01402.21 ACL94571.1 - 4e-08 32.9 1.1 7.4e-08 32.1 1.1 1.5 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family DUF2533 PF10752.9 ACL94571.1 - 0.029 14.8 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) VapB_antitoxin PF09957.9 ACL94571.1 - 0.052 13.5 0.2 0.11 12.4 0.1 1.7 1 1 1 2 2 2 0 Bacterial antitoxin of type II TA system, VapB ParE_toxin PF05016.15 ACL94572.1 - 1.5e-07 31.9 0.0 1.7e-07 31.7 0.0 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE DUF768 PF05589.11 ACL94572.1 - 0.041 13.9 0.1 0.058 13.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF768) Epimerase PF01370.21 ACL94573.1 - 1.3e-09 37.9 0.0 0.00012 21.6 0.0 2.4 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ACL94573.1 - 2.3e-06 27.6 0.0 3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_2 PF03446.15 ACL94573.1 - 0.0014 18.8 0.0 0.0023 18.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GDP_Man_Dehyd PF16363.5 ACL94573.1 - 0.0099 15.3 0.0 2.4 7.5 0.0 2.8 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 ACL94573.1 - 0.012 15.9 0.0 0.021 15.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 ACL94573.1 - 0.014 15.1 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 ACL94573.1 - 0.055 13.1 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF4235 PF14019.6 ACL94573.1 - 0.064 13.4 0.4 0.16 12.1 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) NmrA PF05368.13 ACL94573.1 - 0.064 12.8 0.0 0.085 12.4 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family DUF885 PF05960.11 ACL94574.1 - 1.9e-148 496.4 1.7 2.3e-148 496.2 1.7 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) PfkB PF00294.24 ACL94575.1 - 1.4e-43 149.4 0.0 1.6e-43 149.1 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 ACL94575.1 - 0.065 12.6 0.2 0.1 11.9 0.2 1.3 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase GATase_7 PF13537.6 ACL94575.1 - 0.18 11.7 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase domain Bac_DnaA_C PF08299.11 ACL94576.1 - 8.5e-13 48.1 0.0 1.2e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial dnaA protein helix-turn-helix UPF0176_N PF17773.1 ACL94578.1 - 1.9e-25 89.0 0.0 3e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 ACL94578.1 - 2.8e-07 31.0 0.0 4.5e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese_C PF12368.8 ACL94578.1 - 0.00071 19.9 4.3 0.0033 17.7 4.3 2.0 1 1 0 1 1 1 1 Rhodanase C-terminal Cytochrom_C552 PF02335.15 ACL94578.1 - 0.1 11.5 2.6 0.42 9.5 2.6 1.8 1 1 1 2 2 2 0 Cytochrome c552 SufE PF02657.15 ACL94579.1 - 1.1e-45 154.4 0.0 1.2e-45 154.3 0.0 1.0 1 0 0 1 1 1 1 Fe-S metabolism associated domain HATPase_c PF02518.26 ACL94580.1 - 1.4e-18 67.4 0.0 6.6e-18 65.3 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ACL94580.1 - 2.7e-16 59.3 0.3 1.2e-15 57.3 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 ACL94580.1 - 0.00044 20.2 0.1 0.0014 18.6 0.1 1.9 1 1 1 2 2 2 1 Histidine kinase-like ATPase domain HPTransfase PF10090.9 ACL94580.1 - 0.0017 18.2 0.1 0.0034 17.2 0.1 1.6 1 1 0 1 1 1 1 Histidine phosphotransferase C-terminal domain NOD PF06816.13 ACL94580.1 - 0.14 11.8 0.1 0.34 10.6 0.1 1.5 1 0 0 1 1 1 0 NOTCH protein HATPase_c PF02518.26 ACL94581.2 - 2.6e-25 89.1 0.0 4e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ACL94581.2 - 7.2e-22 77.2 0.3 1.5e-20 73.0 0.1 2.7 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 ACL94581.2 - 0.00081 19.2 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 ACL94581.2 - 0.0045 17.0 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HPTransfase PF10090.9 ACL94581.2 - 0.018 14.8 1.5 0.04 13.7 0.0 2.3 3 0 0 3 3 3 0 Histidine phosphotransferase C-terminal domain DUF1491 PF07372.12 ACL94583.1 - 5.9e-34 116.6 1.0 6.6e-34 116.4 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1491) DUF2470 PF10615.9 ACL94583.1 - 0.14 12.8 0.0 0.18 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2470) FANC_SAP PF18081.1 ACL94583.1 - 0.15 12.3 0.3 0.27 11.4 0.3 1.5 1 1 0 1 1 1 0 Fanconi anemia-associated nuclease SAP domain TPR_14 PF13428.6 ACL94586.1 - 4.4e-05 24.0 25.7 0.00016 22.2 2.7 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat DUF1570 PF07607.11 ACL94586.1 - 5.3e-05 23.5 0.1 0.00016 22.0 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1570) TPR_19 PF14559.6 ACL94586.1 - 6.4e-05 23.4 16.0 0.042 14.4 1.4 4.1 2 2 2 4 4 4 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 ACL94586.1 - 0.00013 21.6 0.8 0.00028 20.5 0.1 1.9 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_9 PF13371.6 ACL94586.1 - 0.0031 17.6 0.6 0.0031 17.6 0.6 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 ACL94586.1 - 0.0079 16.7 2.3 0.0079 16.7 2.3 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_20 PF14561.6 ACL94586.1 - 0.16 12.3 11.7 0.6 10.5 0.7 3.8 3 2 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 ACL94586.1 - 0.2 11.4 8.7 0.26 11.0 3.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_12 PF13424.6 ACL94586.1 - 4.9 7.5 10.9 2.3 8.6 0.3 4.1 3 1 1 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 ACL94586.1 - 5 7.9 31.2 0.41 11.3 0.9 5.5 5 1 1 6 6 6 0 Tetratricopeptide repeat DUF2268 PF10026.9 ACL94587.1 - 0.0005 19.7 0.0 0.00088 18.9 0.0 1.3 1 0 0 1 1 1 1 Predicted Zn-dependent protease (DUF2268) TPR_19 PF14559.6 ACL94587.1 - 0.00083 19.8 12.1 1.4 9.5 0.2 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat DUF1570 PF07607.11 ACL94587.1 - 0.0015 18.8 0.5 0.015 15.6 0.5 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1570) TPR_14 PF13428.6 ACL94587.1 - 0.0027 18.4 18.5 0.062 14.2 0.6 5.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 ACL94587.1 - 0.011 15.4 0.1 0.046 13.4 0.1 2.0 1 0 0 1 1 1 0 TPR repeat HrpB1_HrpK PF09613.10 ACL94587.1 - 0.018 14.7 0.4 0.077 12.6 0.2 2.3 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_17 PF13431.6 ACL94587.1 - 0.088 13.2 0.0 14 6.3 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 ACL94587.1 - 0.28 11.5 3.1 2.8 8.3 0.8 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat GTP_EFTU PF00009.27 ACL94588.1 - 1.4e-49 168.3 0.0 1.8e-49 167.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RF3_C PF16658.5 ACL94588.1 - 1.3e-41 141.5 0.0 2.1e-41 140.8 0.0 1.3 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 ACL94588.1 - 1.7e-06 28.1 0.0 3.3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 ACL94588.1 - 7.5e-05 23.1 0.0 0.00015 22.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 ACL94588.1 - 9e-05 22.5 0.0 0.0002 21.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.10 ACL94588.1 - 0.038 13.4 0.0 0.14 11.5 0.0 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 ACL94588.1 - 0.051 13.1 0.1 0.93 9.0 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B Ras PF00071.22 ACL94588.1 - 0.062 12.9 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Ras family Roc PF08477.13 ACL94588.1 - 0.095 12.9 0.0 0.36 11.1 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Aminotran_1_2 PF00155.21 ACL94589.1 - 1.5e-32 113.2 0.0 1.8e-32 112.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 ACL94589.1 - 0.00012 21.1 0.0 0.00016 20.7 0.0 1.1 1 0 0 1 1 1 1 Allinase SelA PF03841.13 ACL94589.1 - 0.064 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase RNase_H PF00075.24 ACL94590.1 - 0.15 12.2 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 RNase H TonB_C PF03544.14 ACL94593.1 - 4.6e-05 23.8 0.0 7.6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal Bac_export_3 PF01313.19 ACL94594.1 - 1.7e-27 95.2 6.6 1.9e-27 95.0 6.6 1.1 1 0 0 1 1 1 1 Bacterial export proteins, family 3 Bac_export_1 PF01311.20 ACL94594.1 - 0.0004 20.0 7.2 0.00046 19.8 7.2 1.0 1 0 0 1 1 1 1 Bacterial export proteins, family 1 DUF2583 PF10762.9 ACL94594.1 - 0.08 13.4 1.8 0.098 13.1 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) DUF2407_C PF13373.6 ACL94594.1 - 0.31 11.2 1.2 0.34 11.1 1.2 1.2 1 0 0 1 1 1 0 DUF2407 C-terminal domain PHO4 PF01384.20 ACL94594.1 - 0.36 9.8 2.9 0.42 9.6 2.9 1.1 1 0 0 1 1 1 0 Phosphate transporter family Bac_export_1 PF01311.20 ACL94595.1 - 2.8e-59 200.5 30.3 3.3e-59 200.3 30.3 1.0 1 0 0 1 1 1 1 Bacterial export proteins, family 1 Bac_export_2 PF01312.19 ACL94596.1 - 4.7e-122 407.3 2.9 5.3e-122 407.1 2.9 1.0 1 0 0 1 1 1 1 FlhB HrpN YscU SpaS Family EMC3_TMCO1 PF01956.16 ACL94596.1 - 0.38 10.5 4.6 0.62 9.8 1.1 2.1 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like HATPase_c PF02518.26 ACL94597.1 - 1.3e-17 64.3 0.0 2.6e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ACL94597.1 - 1.7e-17 63.6 0.0 3.6e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ACL94597.1 - 1.3e-06 28.4 0.8 2.3e-05 24.3 0.1 3.1 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 ACL94597.1 - 0.028 14.7 0.0 6.2 7.1 0.0 2.6 2 0 0 2 2 2 0 PAS domain PAS_8 PF13188.7 ACL94597.1 - 0.037 14.1 0.0 9.9 6.3 0.0 2.8 2 0 0 2 2 2 0 PAS domain Phage_holin_3_2 PF04550.12 ACL94597.1 - 0.056 14.0 1.4 0.22 12.1 1.4 2.0 1 0 0 1 1 1 0 Phage holin family 2 HATPase_c_3 PF13589.6 ACL94597.1 - 0.061 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 ACL94597.1 - 0.14 12.2 0.0 5.1 7.1 0.0 2.6 2 0 0 2 2 2 0 PAS fold DUF4199 PF13858.6 ACL94598.1 - 3.5e-25 89.3 5.4 4e-25 89.2 5.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4199) DHHC PF01529.20 ACL94598.1 - 0.017 15.3 0.2 0.034 14.3 0.2 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase Herpes_UL25 PF01499.16 ACL94598.1 - 0.11 10.9 0.1 0.14 10.6 0.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family Halogen_Hydrol PF10112.9 ACL94598.1 - 2.4 8.1 3.9 23 4.9 3.9 2.2 1 1 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF2721 PF11026.8 ACL94598.1 - 8.7 6.2 10.9 0.13 12.1 2.9 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) GerE PF00196.19 ACL94599.1 - 1.8e-19 69.0 0.1 2.7e-19 68.5 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 ACL94599.1 - 1.6e-06 27.6 0.0 2.8e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_24 PF13412.6 ACL94599.1 - 1.1e-05 24.9 0.0 1.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Tnp_ISL3 PF13542.6 ACL94599.1 - 6.1e-05 22.4 0.0 0.00013 21.3 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.6 ACL94599.1 - 0.00012 22.1 0.0 0.00033 20.7 0.0 1.7 2 0 0 2 2 1 1 Helix-turn-helix domain HTH_23 PF13384.6 ACL94599.1 - 0.00018 21.2 0.1 0.00078 19.2 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.6 ACL94599.1 - 0.00036 20.2 0.0 0.00062 19.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_20 PF12840.7 ACL94599.1 - 0.00072 19.6 0.0 0.0018 18.3 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AsnC-type PF13404.6 ACL94599.1 - 0.0013 18.6 0.0 0.0028 17.4 0.0 1.7 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_Tnp_1 PF01527.20 ACL94599.1 - 0.0083 16.4 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.6 ACL94599.1 - 0.0088 16.0 0.0 0.018 15.0 0.0 1.5 1 1 0 1 1 1 1 Winged helix-turn helix HTH_40 PF14493.6 ACL94599.1 - 0.017 15.6 0.0 0.022 15.2 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4131 PF13567.6 ACL94599.1 - 0.022 14.4 1.2 0.025 14.3 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) HTH_7 PF02796.15 ACL94599.1 - 0.023 14.7 0.0 0.048 13.7 0.0 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain of resolvase CENP-B_N PF04218.13 ACL94599.1 - 0.03 13.9 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_36 PF13730.6 ACL94599.1 - 0.034 14.1 0.0 0.065 13.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain RP-C PF03428.13 ACL94599.1 - 0.037 13.7 0.1 0.091 12.4 0.1 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain HTH_11 PF08279.12 ACL94599.1 - 0.043 13.8 0.2 2 8.4 0.0 2.3 1 1 1 2 2 2 0 HTH domain HTH_3 PF01381.22 ACL94599.1 - 0.055 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix Sigma70_r4 PF04545.16 ACL94599.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.5 1 1 0 1 1 1 0 Sigma-70, region 4 HTH_30 PF13556.6 ACL94599.1 - 0.069 13.0 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_IclR PF09339.10 ACL94599.1 - 0.075 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_10 PF04967.12 ACL94599.1 - 0.11 12.4 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 HTH DNA binding domain Phage_holin_3_6 PF07332.11 ACL94599.1 - 0.69 10.0 7.9 1.2 9.2 7.9 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF1080 PF06439.11 ACL94601.1 - 1.5e-31 110.0 0.0 1.7e-31 109.8 0.0 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1080) Acetyltransf_3 PF13302.7 ACL94602.1 - 2.9e-22 79.8 0.0 3.3e-22 79.7 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ACL94602.1 - 0.047 13.6 0.0 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_1 PF00583.25 ACL94602.1 - 0.084 13.1 0.0 0.13 12.5 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family GNAT_acetyltran PF12746.7 ACL94602.1 - 0.1 12.1 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase DUF4440 PF14534.6 ACL94603.1 - 1.4e-12 48.0 1.8 1.6e-12 47.8 1.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 ACL94603.1 - 0.00053 20.2 0.3 0.00068 19.9 0.3 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 ACL94603.1 - 0.028 14.6 0.5 0.033 14.3 0.5 1.1 1 0 0 1 1 1 0 SnoaL-like domain DUF885 PF05960.11 ACL94604.1 - 4.9e-163 544.6 0.4 5.6e-163 544.4 0.4 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) EAL PF00563.20 ACL94605.2 - 7.3e-60 202.4 0.2 1.5e-59 201.4 0.2 1.5 1 0 0 1 1 1 1 EAL domain PAS_4 PF08448.10 ACL94605.2 - 6.9e-05 23.1 0.4 0.00038 20.7 0.2 2.3 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 ACL94605.2 - 0.093 13.0 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 PAS fold RecA PF00154.21 ACL94606.1 - 8.5e-145 481.1 1.8 1.2e-144 480.6 1.8 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 ACL94606.1 - 9.3e-12 44.7 0.3 3.8e-11 42.7 0.3 1.8 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 ACL94606.1 - 4.4e-08 32.8 1.8 2.2e-06 27.2 1.8 2.9 1 1 0 1 1 1 1 KaiC ATPase_2 PF01637.18 ACL94606.1 - 1.1e-05 25.4 0.0 2.6e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 ACL94606.1 - 0.00043 19.9 1.0 0.01 15.4 1.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ACL94606.1 - 0.00083 19.8 0.2 0.0022 18.4 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 ACL94606.1 - 0.0021 17.8 0.0 0.0055 16.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 ACL94606.1 - 0.0045 17.4 0.0 0.017 15.5 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CobU PF02283.16 ACL94606.1 - 0.03 13.9 0.0 0.075 12.6 0.0 1.6 1 1 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase ABC_tran PF00005.27 ACL94606.1 - 0.051 14.1 0.0 0.11 13.0 0.0 1.7 1 1 0 1 1 1 0 ABC transporter MobB PF03205.14 ACL94606.1 - 0.11 12.4 0.1 0.47 10.4 0.0 2.1 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AIPR PF10592.9 ACL94606.1 - 0.16 11.6 0.1 0.24 11.0 0.1 1.2 1 0 0 1 1 1 0 AIPR protein Polyoma_lg_T_C PF06431.11 ACL94606.1 - 0.16 10.8 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus Ribonuc_L-PSP PF01042.21 ACL94608.1 - 5.7e-13 48.9 0.1 8.1e-13 48.4 0.1 1.3 1 0 0 1 1 1 1 Endoribonuclease L-PSP Cytochrome_CBB3 PF13442.6 ACL94609.1 - 5.7e-15 55.4 0.0 9.8e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 ACL94609.1 - 4.2e-09 37.4 0.3 6.3e-06 27.3 0.2 2.3 2 0 0 2 2 2 2 Cytochrome c Amino_oxidase PF01593.24 ACL94610.1 - 9.3e-54 183.4 0.1 2.6e-53 181.9 0.1 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ACL94610.1 - 6.7e-13 48.7 1.0 7.6e-12 45.3 0.2 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ACL94610.1 - 5e-07 29.2 0.2 9.3e-07 28.3 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ACL94610.1 - 1.4e-05 24.9 0.7 8.2e-05 22.3 0.2 2.2 2 2 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ACL94610.1 - 1.8e-05 24.2 0.1 3.6e-05 23.2 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ACL94610.1 - 2.6e-05 23.6 0.1 4.9e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 ACL94610.1 - 5.2e-05 22.5 0.9 0.00016 20.9 0.2 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 ACL94610.1 - 7.5e-05 22.1 0.1 0.00047 19.5 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 ACL94610.1 - 0.0001 21.2 0.3 0.00015 20.6 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 ACL94610.1 - 0.00013 21.3 0.2 0.00021 20.7 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 ACL94610.1 - 0.00014 22.3 0.1 0.0072 16.9 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ACL94610.1 - 0.00016 21.2 0.1 0.00021 20.8 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ACL94610.1 - 0.058 12.6 0.4 0.13 11.5 0.4 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 ACL94610.1 - 0.097 11.4 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 MCRA family 3HCDH_N PF02737.18 ACL94610.1 - 0.16 11.8 0.1 0.26 11.2 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Acetyltransf_1 PF00583.25 ACL94612.1 - 1.6e-10 41.3 0.0 2e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ACL94612.1 - 1.2e-08 35.0 0.0 5.6e-08 32.8 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ACL94612.1 - 7.4e-08 32.7 0.0 1.2e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ACL94612.1 - 0.0019 18.3 0.0 0.031 14.3 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain TonB_dep_Rec PF00593.24 ACL94614.1 - 1.1e-34 121.2 31.0 1.1e-34 121.2 31.0 2.4 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 ACL94614.1 - 7.7e-15 55.4 0.3 2.2e-14 53.9 0.3 1.8 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain WYL PF13280.6 ACL94616.1 - 9.3e-34 116.9 0.0 1.5e-33 116.2 0.0 1.4 1 0 0 1 1 1 1 WYL domain Sigma70_ECF PF07638.11 ACL94616.1 - 0.021 14.7 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 ECF sigma factor HTH_17 PF12728.7 ACL94616.1 - 0.024 14.8 0.3 0.096 12.9 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 ACL94616.1 - 0.033 14.0 0.1 0.11 12.3 0.1 1.9 1 0 0 1 1 1 0 Homeodomain-like domain HTH_29 PF13551.6 ACL94616.1 - 0.16 12.0 1.9 0.21 11.7 0.2 2.1 2 0 0 2 2 2 0 Winged helix-turn helix RsmJ PF04378.13 ACL94617.1 - 1.1e-92 309.7 0.0 1.3e-92 309.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA large subunit methyltransferase D, RlmJ Cons_hypoth95 PF03602.15 ACL94617.1 - 0.00042 20.0 0.0 0.0032 17.1 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical protein 95 YAcAr PF10686.9 ACL94617.1 - 0.0054 16.7 0.9 0.69 9.9 0.4 2.7 2 0 0 2 2 2 2 YspA, cpYpsA-related SLOG family Chromate_transp PF02417.15 ACL94618.1 - 1e-55 188.2 52.0 4.3e-34 117.9 13.5 2.5 3 0 0 3 3 3 2 Chromate transporter HHH_5 PF14520.6 ACL94619.2 - 5.3e-06 26.9 1.7 1.3e-05 25.7 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain Cdd1 PF11731.8 ACL94619.2 - 0.00025 21.2 0.0 0.00047 20.3 0.0 1.4 1 0 0 1 1 1 1 Pathogenicity locus HHH PF00633.23 ACL94619.2 - 0.012 15.5 0.7 1.1 9.2 0.1 3.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif IMS_HHH PF11798.8 ACL94619.2 - 0.099 13.0 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 IMS family HHH motif DUF4332 PF14229.6 ACL94619.2 - 0.1 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) TonB_N PF16031.5 ACL94619.2 - 8.8 6.9 22.2 1.6 9.2 2.7 2.6 3 0 0 3 3 3 0 TonB polyproline region TonB_dep_Rec PF00593.24 ACL94620.2 - 1.1e-37 131.0 23.9 1.1e-37 131.0 23.9 2.1 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 ACL94620.2 - 1.6e-24 86.5 3.5 3.4e-24 85.5 3.5 1.6 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain Sulfotransfer_3 PF13469.6 ACL94621.1 - 0.0038 17.6 0.4 2.1 8.6 0.1 2.8 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 ACL94621.1 - 0.019 14.5 0.0 3.6 7.0 0.0 2.4 1 1 1 2 2 2 0 Sulfotransferase domain Sulfotransfer_2 PF03567.14 ACL94621.1 - 0.037 13.9 0.0 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 Sulfotransferase family Amino_oxidase PF01593.24 ACL94622.2 - 4.4e-17 62.5 0.0 3.2e-16 59.7 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ACL94622.2 - 1.3e-13 51.0 0.1 5.3e-13 49.0 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ACL94622.2 - 9e-10 38.7 0.7 1.1e-08 35.1 0.7 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ACL94622.2 - 4.6e-05 22.7 0.5 8.1e-05 21.9 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 ACL94622.2 - 5.4e-05 22.6 0.7 8.8e-05 21.9 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ACL94622.2 - 5.9e-05 22.4 0.3 0.00012 21.4 0.3 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ACL94622.2 - 0.00013 20.8 0.3 0.00021 20.1 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 ACL94622.2 - 0.00027 20.2 0.2 0.00046 19.5 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 ACL94622.2 - 0.0005 19.4 0.2 0.00083 18.7 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ACL94622.2 - 0.0067 17.0 0.1 0.021 15.4 0.3 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ACL94622.2 - 0.013 14.8 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 ACL94622.2 - 0.017 14.2 0.4 0.026 13.6 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A GLF PF03275.13 ACL94622.2 - 0.034 13.9 2.1 0.16 11.6 0.0 2.5 3 0 0 3 3 3 0 UDP-galactopyranose mutase UDPG_MGDP_dh_N PF03721.14 ACL94622.2 - 0.053 13.1 0.2 0.088 12.4 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 ACL94622.2 - 0.053 14.0 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 ACL94622.2 - 0.097 11.7 0.1 0.18 10.8 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 ACL94622.2 - 0.16 11.2 0.2 0.32 10.3 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.16 ACL94624.1 - 5.9e-19 68.2 41.3 5.9e-19 68.2 41.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily SDF PF00375.18 ACL94626.1 - 9.4e-108 360.7 33.7 1.1e-107 360.5 33.7 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Glyco_hydro_3 PF00933.21 ACL94627.1 - 1.6e-70 238.0 0.0 2.2e-70 237.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 ACL94627.1 - 5.1e-53 180.1 0.0 7.7e-53 179.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 ACL94627.1 - 1.5e-21 76.3 0.0 3.6e-21 75.0 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF11 PF01345.18 ACL94627.1 - 0.023 15.0 0.0 5.9 7.3 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function DUF11 LPD7 PF18821.1 ACL94627.1 - 0.21 11.8 0.8 1.2 9.3 0.3 2.5 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 7 CAAP1 PF15335.6 ACL94628.1 - 3.1e-35 120.5 0.0 1.4 9.5 0.0 30.7 25 10 7 36 36 36 3 Caspase activity and apoptosis inhibitor 1 Hepsin-SRCR PF09272.10 ACL94628.1 - 3e-11 43.8 38.4 40 4.8 0.0 24.2 17 10 12 30 30 30 0 Hepsin, SRCR domain Phage_TAC_7 PF10109.9 ACL94628.1 - 9.3e-08 32.1 92.9 15 5.8 0.1 30.3 9 6 22 33 33 33 5 Phage tail assembly chaperone proteins, E, or 41 or 14 Luciferase_3H PF10284.9 ACL94628.1 - 0.0019 18.3 4.6 5.2e+02 0.9 0.0 12.4 12 0 0 12 12 12 0 Luciferase helical bundle domain DAHP_snth_FXD PF18152.1 ACL94628.1 - 0.067 13.0 0.1 1.5 8.7 0.0 3.4 2 0 0 2 2 2 0 DAHP synthase ferredoxin-like domain LRR_8 PF13855.6 ACL94628.1 - 0.27 11.0 27.1 44 3.9 0.0 13.3 14 0 0 14 14 14 0 Leucine rich repeat Glyco_transf_41 PF13844.6 ACL94629.1 - 2.8e-85 286.6 0.0 7.4e-44 150.0 0.0 2.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_12 PF13424.6 ACL94629.1 - 8.8e-08 32.3 5.3 2.6e-05 24.4 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 ACL94629.1 - 3.3e-06 26.8 0.5 0.025 14.7 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 ACL94629.1 - 1.4e-05 25.5 13.0 3.5 8.7 0.0 6.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 ACL94629.1 - 9.8e-05 22.3 0.6 0.28 11.5 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 ACL94629.1 - 0.00088 19.0 2.6 0.38 10.7 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 ACL94629.1 - 0.00093 19.4 2.8 1.8 9.1 0.0 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 ACL94629.1 - 0.0058 16.3 3.7 0.015 15.0 0.1 3.2 3 0 0 3 3 3 1 TPR repeat TPR_16 PF13432.6 ACL94629.1 - 0.046 14.4 1.2 0.046 14.4 1.2 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat ANAPC5 PF12862.7 ACL94629.1 - 0.15 12.2 0.3 0.37 10.9 0.0 1.7 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 5 TPR_9 PF13371.6 ACL94629.1 - 0.44 10.7 0.1 0.44 10.7 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 ACL94629.1 - 0.8 10.5 5.9 2.3 9.0 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Methyltransf_21 PF05050.12 ACL94630.1 - 5.4e-13 49.3 0.0 9e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain Nucleotid_trans PF03407.16 ACL94630.1 - 0.014 15.4 0.1 0.022 14.8 0.1 1.2 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Methyltransf_12 PF08242.12 ACL94630.1 - 0.13 13.0 0.0 21 5.9 0.0 2.7 2 0 0 2 2 2 0 Methyltransferase domain MaoC_dehydrat_N PF13452.6 ACL94631.1 - 1.3e-06 28.6 0.0 3.2e-05 24.1 0.0 2.4 2 1 0 2 2 2 1 N-terminal half of MaoC dehydratase Acyl-CoA_dh_1 PF00441.24 ACL94632.1 - 6.6e-35 120.5 0.7 1.1e-34 119.9 0.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ACL94632.1 - 1.1e-23 84.0 0.1 2.5e-23 82.9 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ACL94632.1 - 6.3e-23 80.8 0.1 1.2e-22 79.9 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ACL94632.1 - 2.5e-15 56.9 0.6 2.5e-15 56.9 0.6 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 ACL94632.1 - 0.07 13.7 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Thiolase_N PF00108.23 ACL94633.1 - 1.4e-72 244.2 0.2 1.7e-72 243.9 0.2 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ACL94633.1 - 8.2e-43 145.0 1.1 1.9e-42 143.8 1.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ACL94633.1 - 2.1e-06 27.5 0.5 2.1e-06 27.5 0.5 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain TonB_dep_Rec PF00593.24 ACL94635.1 - 8.1e-53 180.9 32.2 8.1e-53 180.9 32.2 2.3 1 1 0 2 2 2 1 TonB dependent receptor OMP_b-brl_3 PF14905.6 ACL94635.1 - 1e-27 97.2 1.3 1e-27 97.2 1.3 2.3 2 0 0 2 2 2 1 Outer membrane protein beta-barrel family Plug PF07715.15 ACL94635.1 - 4e-13 49.9 0.3 1e-12 48.6 0.3 1.7 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain Poty_coat PF00767.18 ACL94635.1 - 0.12 11.9 0.0 3.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Potyvirus coat protein Hpt PF01627.23 ACL94636.1 - 1.1e-05 25.6 0.2 1.5e-05 25.1 0.2 1.4 1 0 0 1 1 1 1 Hpt domain AMP_N PF05195.16 ACL94636.1 - 0.11 12.2 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain AIM24 PF01987.17 ACL94637.1 - 3.1e-64 216.5 0.5 3.7e-64 216.2 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF4115 PF13464.6 ACL94637.1 - 0.11 12.7 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4115) CM_2 PF01817.21 ACL94638.2 - 2.5e-15 56.6 1.1 3e-15 56.3 1.1 1.1 1 0 0 1 1 1 1 Chorismate mutase type II CDPS PF16715.5 ACL94638.2 - 0.012 15.3 0.3 0.015 15.0 0.3 1.1 1 0 0 1 1 1 0 Cyclodipeptide synthase RPA_interact_N PF14766.6 ACL94638.2 - 0.067 12.8 0.1 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 Replication protein A interacting N-terminal LysR_substrate PF03466.20 ACL94639.1 - 3e-42 144.4 2.2 4.9e-42 143.7 2.2 1.4 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 ACL94639.1 - 1.4e-19 69.8 0.5 1.4e-19 69.8 0.5 2.3 2 1 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_24 PF13412.6 ACL94639.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Titin_Ig-rpts PF06582.12 ACL94639.1 - 0.15 12.0 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Titin repeat TP_methylase PF00590.20 ACL94640.1 - 1.1e-49 169.2 5.2 1.4e-49 168.9 5.2 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Radical_SAM PF04055.21 ACL94640.1 - 0.0089 16.4 0.0 0.018 15.4 0.0 1.6 1 1 0 1 1 1 1 Radical SAM superfamily PIN_10 PF18478.1 ACL94640.1 - 0.015 15.5 0.1 0.08 13.2 0.0 2.2 1 1 1 2 2 2 0 PIN like domain DUF2849 PF11011.8 ACL94641.1 - 4.2e-22 78.6 0.1 6.3e-22 78.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2849) NIR_SIR PF01077.22 ACL94642.1 - 1.4e-55 187.2 0.0 3.1e-40 137.3 0.0 2.3 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 ACL94642.1 - 7.7e-36 121.8 0.1 2.3e-18 65.8 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain DUF934 PF06073.12 ACL94643.1 - 7.4e-38 128.7 0.1 9.9e-38 128.3 0.1 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF934) PAPS_reduct PF01507.19 ACL94644.1 - 3.4e-37 128.1 0.0 4.1e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Penicil_amidase PF01804.18 ACL94645.1 - 1.9e-116 390.7 11.2 2.1e-116 390.5 11.2 1.0 1 0 0 1 1 1 1 Penicillin amidase 3D PF06725.11 ACL94646.1 - 4.5e-12 46.0 0.0 7.2e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 3D domain GST_C PF00043.25 ACL94647.1 - 4.8e-11 42.7 0.0 6.8e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ACL94647.1 - 4.3e-08 33.4 0.0 7.7e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ACL94647.1 - 1.8e-07 31.3 0.0 2.3e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ACL94647.1 - 4.7e-07 29.7 0.3 1.2e-06 28.4 0.3 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ACL94647.1 - 1.2e-06 28.8 0.0 2.5e-06 27.8 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ACL94647.1 - 4.5e-05 23.7 0.0 7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 ACL94647.1 - 0.066 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain S1-P1_nuclease PF02265.16 ACL94648.1 - 1.2e-06 28.5 0.0 2.1e-05 24.4 0.0 2.0 1 1 0 1 1 1 1 S1/P1 Nuclease Zn_dep_PLPC PF00882.18 ACL94648.1 - 0.084 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Zinc dependent phospholipase C NUDIX PF00293.28 ACL94649.1 - 3.5e-12 46.5 0.1 4.1e-12 46.3 0.1 1.0 1 0 0 1 1 1 1 NUDIX domain TonB_C PF03544.14 ACL94651.1 - 0.0067 16.8 0.0 0.01 16.3 0.0 1.3 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal PCSK9_C3 PF18463.1 ACL94651.1 - 0.057 13.7 0.2 0.08 13.2 0.2 1.2 1 0 0 1 1 1 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain Rhodopsin_N PF10413.9 ACL94651.1 - 0.19 11.6 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Amino terminal of the G-protein receptor rhodopsin Sigma70_r4_2 PF08281.12 ACL94652.2 - 1.5e-12 47.0 0.2 5e-12 45.3 0.1 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 ACL94652.2 - 5.4e-07 29.3 1.8 2.1e-06 27.4 1.8 2.0 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 ACL94652.2 - 2.8e-06 26.8 0.7 2.8e-06 26.8 0.7 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 GerE PF00196.19 ACL94652.2 - 0.0011 18.5 0.0 0.002 17.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_ECF PF07638.11 ACL94652.2 - 0.0021 18.0 0.6 0.011 15.6 0.6 1.9 1 1 0 1 1 1 1 ECF sigma factor Remorin_C PF03763.13 ACL94652.2 - 0.059 13.3 0.2 0.088 12.7 0.2 1.3 1 0 0 1 1 1 0 Remorin, C-terminal region DUF1843 PF08898.10 ACL94652.2 - 0.094 13.2 1.9 0.19 12.3 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) HTH_11 PF08279.12 ACL94652.2 - 0.13 12.2 0.2 1.7 8.6 0.1 2.3 2 0 0 2 2 2 0 HTH domain FecR PF04773.13 ACL94653.1 - 2.9e-24 85.5 0.4 5e-24 84.8 0.4 1.4 1 0 0 1 1 1 1 FecR protein DUF4880 PF16220.5 ACL94653.1 - 0.003 17.4 15.7 0.003 17.4 15.7 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4880) DUF3040 PF11239.8 ACL94653.1 - 0.032 14.5 0.2 0.1 12.9 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) TonB_dep_Rec PF00593.24 ACL94654.2 - 2e-40 140.1 23.8 2e-40 140.1 23.8 2.0 1 1 0 2 2 2 1 TonB dependent receptor OMP_b-brl_3 PF14905.6 ACL94654.2 - 9.6e-17 61.0 0.2 1.4e-14 53.9 0.1 2.5 2 0 0 2 2 2 2 Outer membrane protein beta-barrel family Plug PF07715.15 ACL94654.2 - 1.6e-15 57.6 0.7 4e-15 56.3 0.7 1.8 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain STN PF07660.14 ACL94654.2 - 6.5e-09 35.5 0.0 2.1e-08 33.8 0.0 2.0 1 0 0 1 1 1 1 Secretin and TonB N terminus short domain MFS_1 PF07690.16 ACL94656.1 - 2.4e-41 141.8 67.1 1.7e-38 132.5 53.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 ACL94656.1 - 0.0012 17.9 31.8 0.0031 16.6 14.2 3.1 1 1 2 3 3 3 3 Nucleoside H+ symporter MFS_4 PF06779.14 ACL94656.1 - 0.0029 16.9 38.5 0.004 16.5 38.5 1.0 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB ROK PF00480.20 ACL94657.1 - 3.8e-58 197.3 0.0 4.4e-58 197.1 0.0 1.0 1 0 0 1 1 1 1 ROK family Glucokinase PF02685.16 ACL94657.1 - 0.21 10.6 1.9 2.7 6.9 1.4 2.1 2 0 0 2 2 2 0 Glucokinase Alpha-amylase PF00128.24 ACL94658.2 - 1.6e-42 146.3 0.0 8.4e-38 130.8 0.0 2.1 2 0 0 2 2 2 2 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 ACL94658.2 - 3e-08 33.7 0.0 7e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 ACL94658.2 - 0.0058 15.8 0.0 0.0098 15.0 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain TonB_dep_Rec PF00593.24 ACL94659.1 - 1.1e-25 91.5 21.9 1.1e-25 91.5 21.9 2.1 1 1 0 2 2 2 1 TonB dependent receptor Plug PF07715.15 ACL94659.1 - 1.6e-17 64.0 2.4 1.6e-17 64.0 2.4 2.2 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain Peripla_BP_3 PF13377.6 ACL94660.1 - 1.1e-34 120.2 0.3 1.8e-34 119.5 0.3 1.4 1 0 0 1 1 1 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 ACL94660.1 - 4.1e-15 55.9 0.0 5.2e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 ACL94660.1 - 1.7e-13 50.1 0.0 3e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 ACL94660.1 - 6.4e-11 42.3 0.0 9.5e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein domain HTH_31 PF13560.6 ACL94660.1 - 0.0016 18.7 1.2 0.026 14.9 0.1 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_38 PF13936.6 ACL94660.1 - 0.0022 17.7 0.1 0.0091 15.7 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AsnC-type PF13404.6 ACL94660.1 - 0.0064 16.3 0.4 0.048 13.5 0.2 2.4 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_Crp_2 PF13545.6 ACL94660.1 - 0.011 15.6 0.2 0.048 13.6 0.0 2.2 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_24 PF13412.6 ACL94660.1 - 0.024 14.2 0.1 0.077 12.6 0.1 1.9 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_3 PF01381.22 ACL94660.1 - 0.027 14.5 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix Helicase_C_3 PF13625.6 ACL94660.1 - 0.051 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Helicase conserved C-terminal domain HTH_23 PF13384.6 ACL94660.1 - 0.056 13.3 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 ACL94660.1 - 0.068 12.6 0.2 0.25 10.8 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_IclR PF09339.10 ACL94660.1 - 0.11 12.3 0.1 0.11 12.3 0.1 2.5 3 0 0 3 3 3 0 IclR helix-turn-helix domain HTH_36 PF13730.6 ACL94660.1 - 0.18 11.8 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain TonB_dep_Rec PF00593.24 ACL94661.1 - 1.5e-31 110.8 19.8 2.1e-31 110.3 19.8 1.3 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 ACL94661.1 - 3.4e-09 37.2 0.5 6.9e-09 36.2 0.5 1.5 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 ACL94661.1 - 0.0012 17.9 0.0 0.0016 17.5 0.0 1.2 1 0 0 1 1 1 1 Outer membrane protein beta-barrel family DUF2256 PF10013.9 ACL94662.1 - 5e-20 71.3 8.4 5.8e-20 71.1 8.4 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) zf_C2H2_13 PF18508.1 ACL94662.1 - 0.055 13.1 0.1 0.088 12.4 0.1 1.3 1 0 0 1 1 1 0 Zinc finger domain RmlD_sub_bind PF04321.17 ACL94663.1 - 1.2e-104 349.4 0.0 1.4e-104 349.2 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 ACL94663.1 - 3.7e-18 65.9 0.0 5.6e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ACL94663.1 - 2.1e-12 47.1 1.3 6.1e-11 42.3 0.0 2.1 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ACL94663.1 - 2.3e-06 26.9 0.8 0.00013 21.2 0.1 2.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 ACL94663.1 - 0.015 14.5 0.0 0.034 13.3 0.0 1.7 1 1 0 1 1 1 0 Male sterility protein NTP_transferase PF00483.23 ACL94664.1 - 9.6e-70 235.0 0.0 1.2e-69 234.7 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 ACL94664.1 - 5e-10 40.0 0.0 7.6e-10 39.4 0.0 1.4 2 0 0 2 2 2 1 MobA-like NTP transferase domain IspD PF01128.19 ACL94664.1 - 0.016 15.0 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GPHH PF16905.5 ACL94664.1 - 0.17 11.7 0.0 0.51 10.1 0.0 1.7 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated OMP_b-brl_3 PF14905.6 ACL94665.1 - 1.3e-76 258.2 0.1 5.4e-75 252.9 0.0 2.0 2 0 0 2 2 2 2 Outer membrane protein beta-barrel family TonB_dep_Rec PF00593.24 ACL94665.1 - 7.7e-20 72.2 23.6 5e-19 69.5 23.6 2.0 1 1 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 ACL94665.1 - 3.1e-10 40.6 2.1 8.2e-10 39.2 0.8 2.3 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain Porin_4 PF13609.6 ACL94665.1 - 0.024 14.4 0.6 0.024 14.4 0.6 3.2 3 0 0 3 3 3 0 Gram-negative porin VWA_3_C PF18571.1 ACL94666.1 - 0.054 13.4 0.5 0.15 12.0 0.5 1.7 1 0 0 1 1 1 0 von Willebrand factor type A C-terminal domain Peptidase_M1 PF01433.20 ACL94667.1 - 3.2e-12 46.5 0.0 5.1e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain TonB_dep_Rec PF00593.24 ACL94668.1 - 8.3e-24 85.3 15.0 8.7e-24 85.2 14.4 1.4 1 1 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 ACL94668.1 - 6.7e-12 45.9 0.0 1.5e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain GDP_Man_Dehyd PF16363.5 ACL94669.1 - 1.6e-50 172.4 0.0 2.8e-50 171.6 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ACL94669.1 - 5e-48 163.7 0.0 6e-48 163.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 ACL94669.1 - 2.5e-10 39.9 0.0 1.3e-05 24.5 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 ACL94669.1 - 3.2e-08 32.9 0.0 5.4e-08 32.2 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ACL94669.1 - 2.2e-06 27.0 0.0 3.1e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 ACL94669.1 - 3.5e-06 26.4 0.0 0.0012 18.0 0.0 2.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 ACL94669.1 - 0.0026 17.3 0.0 0.004 16.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ACL94669.1 - 0.11 12.3 0.0 0.23 11.4 0.0 1.4 2 0 0 2 2 2 0 KR domain ABC_tran PF00005.27 ACL94670.1 - 8.1e-26 91.2 0.0 1.3e-25 90.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ACL94670.1 - 3.7e-08 33.5 0.1 2.9e-05 24.1 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ACL94670.1 - 0.0087 16.5 0.7 0.029 14.8 0.7 2.1 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 ACL94670.1 - 0.0094 15.4 0.0 3.5 7.0 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ACL94670.1 - 0.0094 15.7 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 ACL94670.1 - 0.016 15.5 0.1 0.11 12.8 0.1 2.3 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 ACL94670.1 - 0.023 14.9 0.1 0.55 10.5 0.1 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit BCA_ABC_TP_C PF12399.8 ACL94670.1 - 0.035 14.0 0.1 0.074 13.0 0.1 1.6 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter ABC2_membrane PF01061.24 ACL94671.1 - 3.3e-12 46.3 10.6 3.3e-12 46.3 10.6 1.4 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 ACL94671.1 - 1.3e-11 44.3 12.9 2.2e-11 43.5 12.9 1.3 1 1 0 1 1 1 1 ABC-2 family transporter protein Trep_Strep PF09605.10 ACL94671.1 - 5.5 6.9 15.2 0.54 10.2 5.3 2.4 2 1 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) HisKA_3 PF07730.13 ACL94672.1 - 4.7e-16 59.0 7.6 4.7e-16 59.0 7.6 3.0 2 1 1 3 3 3 1 Histidine kinase HATPase_c PF02518.26 ACL94672.1 - 0.00035 21.0 0.0 0.047 14.2 0.0 2.4 1 1 1 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 ACL94672.1 - 0.0015 18.5 0.0 0.0015 18.5 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain DUF4233 PF14017.6 ACL94672.1 - 0.0021 18.4 3.4 0.0021 18.4 3.4 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF4233) TcpE PF12648.7 ACL94672.1 - 0.092 13.3 0.5 0.27 11.8 0.1 1.9 2 0 0 2 2 2 0 TcpE family Response_reg PF00072.24 ACL94673.1 - 1.1e-23 83.5 0.0 1.5e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain GerE PF00196.19 ACL94673.1 - 7.3e-19 67.1 0.0 1.1e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 ACL94673.1 - 3.3e-10 39.5 0.0 7.1e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 ACL94673.1 - 1.7e-07 30.6 0.0 2.9e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 ACL94673.1 - 5.9e-06 25.9 0.0 1.3e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 ACL94673.1 - 1.2e-05 25.0 0.0 3e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.6 ACL94673.1 - 7.2e-05 22.7 0.1 0.00021 21.2 0.1 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_24 PF13412.6 ACL94673.1 - 8.1e-05 22.1 0.1 0.00021 20.8 0.1 1.8 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_10 PF04967.12 ACL94673.1 - 0.00016 21.4 0.1 0.016 15.0 0.1 2.6 1 1 0 1 1 1 1 HTH DNA binding domain HTH_Tnp_ISL3 PF13542.6 ACL94673.1 - 0.00069 19.0 0.0 0.0014 18.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_40 PF14493.6 ACL94673.1 - 0.0011 19.4 0.0 0.002 18.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 ACL94673.1 - 0.011 15.5 0.0 0.038 13.8 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_11 PF08279.12 ACL94673.1 - 0.014 15.4 0.1 0.052 13.5 0.0 2.0 2 0 0 2 2 2 0 HTH domain Phage_terminase PF10668.9 ACL94673.1 - 0.016 15.2 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 Phage terminase small subunit HTH_28 PF13518.6 ACL94673.1 - 0.021 15.0 0.0 0.057 13.6 0.0 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_3 PF01381.22 ACL94673.1 - 0.021 14.9 0.0 0.051 13.6 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix HrcA_DNA-bdg PF03444.15 ACL94673.1 - 0.026 14.1 0.0 0.062 13.0 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding HTH_7 PF02796.15 ACL94673.1 - 0.039 14.0 0.0 0.079 13.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase DUF742 PF05331.11 ACL94673.1 - 0.042 13.7 0.2 0.091 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF742) HTH_AsnC-type PF13404.6 ACL94673.1 - 0.042 13.7 0.0 0.17 11.8 0.0 2.0 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_IclR PF09339.10 ACL94673.1 - 0.077 12.8 0.0 0.29 11.0 0.0 2.0 2 0 0 2 2 2 0 IclR helix-turn-helix domain RepB PF07506.11 ACL94673.1 - 0.13 12.4 0.1 0.34 11.0 0.0 1.7 2 0 0 2 2 2 0 RepB plasmid partitioning protein FMN_dh PF01070.18 ACL94674.1 - 6.5e-127 423.3 2.7 7.5e-127 423.1 2.7 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 ACL94674.1 - 1.6e-06 27.4 2.5 6.2e-06 25.4 1.5 2.3 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 ACL94674.1 - 2.9e-05 23.6 4.7 4.9e-05 22.9 4.7 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 ACL94674.1 - 0.00087 18.5 0.8 0.0014 17.8 0.8 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 ACL94674.1 - 0.0048 16.2 0.9 2.3 7.5 0.3 2.2 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 ACL94674.1 - 0.038 13.5 0.4 0.26 10.7 0.2 2.1 1 1 1 2 2 2 0 Histidine biosynthesis protein DHO_dh PF01180.21 ACL94674.1 - 0.038 13.2 0.1 0.059 12.6 0.1 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase IGPS PF00218.21 ACL94674.1 - 0.08 12.1 0.0 0.19 10.9 0.0 1.6 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase NTP_transf_3 PF12804.7 ACL94675.1 - 3.6e-14 53.4 0.0 4.3e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 ACL94675.1 - 4.2e-12 46.2 0.0 5.7e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase IspD PF01128.19 ACL94675.1 - 6.5e-05 22.8 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DUF1421 PF07223.11 ACL94675.1 - 0.028 14.2 0.0 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 UBA-like domain (DUF1421) NTP_transf_3 PF12804.7 ACL94676.3 - 1.5e-17 64.4 3.1 1.5e-17 64.4 3.1 2.1 1 1 0 2 2 2 2 MobA-like NTP transferase domain Ala_racemase_N PF01168.20 ACL94676.3 - 0.094 12.3 0.9 0.21 11.2 0.3 1.9 2 0 0 2 2 2 0 Alanine racemase, N-terminal domain LptF_LptG PF03739.14 ACL94678.1 - 1.9e-62 211.2 0.5 2.2e-62 211.0 0.5 1.0 1 0 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG LptF_LptG PF03739.14 ACL94679.1 - 2e-63 214.4 3.2 2.3e-63 214.2 3.2 1.0 1 0 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG PqiA PF04403.13 ACL94679.1 - 0.82 9.5 10.7 0.15 11.9 0.4 3.1 2 1 1 3 3 3 0 Paraquat-inducible protein A HIT PF01230.23 ACL94680.1 - 0.0003 21.5 0.0 0.00052 20.7 0.0 1.3 1 0 0 1 1 1 1 HIT domain Metallophos PF00149.28 ACL94681.1 - 2.1e-13 51.2 0.0 4e-13 50.3 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ACL94681.1 - 1.5e-07 31.8 0.0 3.2e-07 30.7 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CDP-OH_P_transf PF01066.21 ACL94682.1 - 6.3e-13 49.3 0.5 6.3e-13 49.3 0.5 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DAGK_cat PF00781.24 ACL94683.3 - 1.5e-09 37.5 0.0 2.9e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 ACL94683.3 - 0.00095 18.4 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Aminotran_1_2 PF00155.21 ACL94685.1 - 1.1e-57 195.9 0.0 1.3e-57 195.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ACL94685.1 - 1.7e-08 34.1 0.0 2.5e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 ACL94685.1 - 1.9e-06 26.7 0.0 2.8e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 ACL94685.1 - 0.00022 20.7 1.8 0.0023 17.3 1.8 2.1 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 ACL94685.1 - 0.00088 18.3 0.0 0.0028 16.7 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_3 PF00202.21 ACL94685.1 - 0.0028 16.4 0.0 0.0056 15.4 0.0 1.5 1 1 1 2 2 2 1 Aminotransferase class-III OKR_DC_1 PF01276.20 ACL94685.1 - 0.039 12.7 0.0 0.9 8.2 0.0 2.1 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain FeoA PF04023.14 ACL94685.1 - 0.04 14.2 0.2 0.27 11.5 0.1 2.3 2 0 0 2 2 2 0 FeoA domain PP-binding PF00550.25 ACL94686.1 - 4.5e-09 36.5 0.7 6e-09 36.1 0.6 1.3 1 1 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 ACL94687.1 - 9.5e-19 67.8 0.0 4.2e-18 65.7 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ACL94687.1 - 2.2e-18 66.8 0.6 3e-18 66.4 0.6 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ACL94687.1 - 6.1e-14 51.7 0.0 6.7e-11 41.7 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ACL94687.1 - 1.9e-11 43.6 0.0 1.6e-09 37.3 0.0 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 ACL94687.1 - 2.6e-11 43.2 0.3 0.0019 17.5 0.1 3.1 1 1 2 3 3 3 3 Male sterility protein NmrA PF05368.13 ACL94687.1 - 1.6e-10 41.0 0.0 2.2e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 ACL94687.1 - 1.8e-05 24.3 0.1 0.00017 21.1 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ACL94687.1 - 0.00016 21.7 0.4 0.0011 18.9 0.4 2.4 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 ACL94687.1 - 0.0036 16.7 0.0 0.0085 15.5 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ACL94687.1 - 0.011 15.0 0.0 0.11 11.7 0.0 2.0 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein AMP-binding PF00501.28 ACL94688.1 - 2.3e-64 217.5 0.0 3.7e-64 216.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C_2 PF14535.6 ACL94688.1 - 0.0044 17.3 0.0 0.0078 16.5 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Polysacc_synt_C PF14667.6 ACL94689.1 - 0.00014 21.9 10.0 0.00014 21.9 10.0 4.4 2 2 3 5 5 5 1 Polysaccharide biosynthesis C-terminal domain Glyphos_transf PF04464.14 ACL94690.1 - 0.0017 17.4 0.0 0.0028 16.7 0.0 1.4 1 1 0 1 1 1 1 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase LptC PF06835.13 ACL94691.1 - 1.1e-18 67.4 0.0 1.3e-18 67.2 0.0 1.0 1 0 0 1 1 1 1 Lipopolysaccharide-assembly, LptC-related DUF2568 PF10823.8 ACL94691.1 - 0.047 14.0 0.5 0.11 12.8 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2568) OstA PF03968.14 ACL94691.1 - 0.069 13.4 0.1 0.5 10.6 0.0 2.3 1 1 1 2 2 2 0 OstA-like protein RskA PF10099.9 ACL94691.1 - 3.5 7.9 10.3 5.2 7.3 9.8 1.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Bac_luciferase PF00296.20 ACL94692.1 - 1.6e-71 241.3 7.0 2.2e-71 240.9 7.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Isochorismatase PF00857.20 ACL94693.1 - 1.2e-43 149.3 0.0 1.5e-43 149.0 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DSBA PF01323.20 ACL94694.1 - 1e-25 90.7 0.0 3.2e-22 79.3 0.0 2.5 3 0 0 3 3 3 2 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 ACL94694.1 - 0.011 15.9 0.0 0.026 14.7 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin Sulfatase PF00884.23 ACL94695.1 - 5.7e-71 239.4 0.0 1.3e-69 235.0 0.0 2.4 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 ACL94695.1 - 2.3e-09 37.3 0.2 4.6e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 ACL94695.1 - 0.0025 18.6 0.0 0.0061 17.3 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF1501 PF07394.12 ACL94695.1 - 0.0076 15.4 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) DUF4994 PF16385.5 ACL94695.1 - 0.012 15.5 0.0 0.029 14.3 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function DUF229 PF02995.17 ACL94695.1 - 0.07 11.7 0.0 0.091 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) FGE-sulfatase PF03781.16 ACL94696.3 - 2.4e-92 309.2 2.4 3e-92 308.9 2.4 1.1 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DUF1330 PF07045.11 ACL94697.1 - 5.8e-06 26.6 0.1 2.1e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1330) EthD PF07110.11 ACL94697.1 - 0.0015 19.6 0.0 0.31 12.2 0.0 2.3 2 0 0 2 2 2 2 EthD domain Abhydrolase_1 PF00561.20 ACL94698.1 - 6.5e-18 65.3 0.0 8.8e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ACL94698.1 - 1.1e-17 65.3 1.2 1.4e-17 65.0 1.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ACL94698.1 - 1.8e-10 40.5 0.0 3.5e-10 39.6 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 ACL94698.1 - 0.06 12.3 0.0 0.084 11.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Lactamase_B PF00753.27 ACL94699.1 - 8.2e-25 88.0 1.2 1.5e-24 87.1 1.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ACL94699.1 - 2.3e-16 59.9 0.0 4.5e-16 59.0 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ACL94699.1 - 0.025 14.4 0.0 0.1 12.5 0.0 2.1 1 1 0 1 1 1 0 Beta-lactamase superfamily domain TetR_N PF00440.23 ACL94700.1 - 0.022 14.5 0.0 0.047 13.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family KGG PF10685.9 ACL94701.1 - 1.1e-12 47.8 8.5 1e-06 28.8 0.5 2.7 3 0 0 3 3 3 2 Stress-induced bacterial acidophilic repeat motif EF-hand_7 PF13499.6 ACL94703.2 - 1.2e-11 44.8 0.2 0.003 18.0 0.0 3.7 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 ACL94703.2 - 1.8e-10 39.9 2.4 0.026 14.4 0.1 3.8 2 2 2 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 ACL94703.2 - 4.3e-10 38.4 0.2 0.1 12.2 0.0 3.6 3 1 0 3 3 3 3 EF hand EF-hand_5 PF13202.6 ACL94703.2 - 2.9e-09 36.0 1.9 0.017 14.6 0.0 3.6 3 1 1 4 4 4 3 EF hand EF-hand_8 PF13833.6 ACL94703.2 - 2.1e-05 24.2 0.0 0.61 10.0 0.0 3.4 3 0 0 3 3 3 3 EF-hand domain pair HATPase_c PF02518.26 ACL94704.1 - 1.4e-22 80.4 0.0 2.8e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 ACL94704.1 - 1e-06 29.0 0.5 3.2e-06 27.4 0.5 1.9 1 0 0 1 1 1 1 HAMP domain HisKA PF00512.25 ACL94704.1 - 8.9e-05 22.4 0.2 0.00032 20.7 0.1 2.1 1 1 1 2 2 2 1 His Kinase A (phospho-acceptor) domain Apolipoprotein PF01442.18 ACL94704.1 - 0.035 14.0 0.1 0.081 12.8 0.1 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain HATPase_c_3 PF13589.6 ACL94704.1 - 0.036 13.9 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ACL94705.1 - 2.2e-29 101.9 0.0 6.1e-29 100.5 0.0 1.7 2 0 0 2 2 2 1 Response regulator receiver domain Trans_reg_C PF00486.28 ACL94705.1 - 8.8e-22 77.0 0.5 1.7e-21 76.1 0.0 1.7 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Ish1 PF10281.9 ACL94705.1 - 0.14 12.4 0.3 9.7 6.6 0.0 2.6 3 0 0 3 3 3 0 Putative stress-responsive nuclear envelope protein Lactamase_B PF00753.27 ACL94706.2 - 1.2e-33 116.8 4.2 1.4e-33 116.6 4.2 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ACL94706.2 - 0.0027 17.2 0.1 0.0038 16.8 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain AA_permease_2 PF13520.6 ACL94707.2 - 1.6e-56 192.0 45.4 2.1e-56 191.6 45.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ACL94707.2 - 3.2e-40 138.1 43.4 4.2e-40 137.8 43.4 1.1 1 0 0 1 1 1 1 Amino acid permease HrpB_C PF08482.10 ACL94708.1 - 1.1e-48 165.1 0.0 1.8e-48 164.3 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent helicase C-terminal Helicase_C PF00271.31 ACL94708.1 - 3.6e-13 49.8 0.0 6.6e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 ACL94708.1 - 6.8e-11 42.4 0.0 1.2e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.29 ACL94708.1 - 8.2e-07 29.0 0.0 2.7e-06 27.3 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 ACL94708.1 - 0.00095 18.9 0.1 0.0021 17.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 ACL94708.1 - 0.034 14.1 0.0 0.068 13.1 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_19 PF13245.6 ACL94708.1 - 0.1 12.9 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Imm8 PF15586.6 ACL94709.1 - 9.2e-30 103.0 0.0 1.1e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Immunity protein 8 SpoU_methylase PF00588.19 ACL94710.1 - 3.9e-32 111.4 0.0 7.2e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 ACL94710.1 - 1e-10 41.8 0.0 1.7e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Prismane PF03063.20 ACL94710.1 - 0.045 12.5 0.0 0.07 11.8 0.0 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Methyltrans_SAM PF10672.9 ACL94711.1 - 9.1e-08 31.6 0.0 1.6e-07 30.8 0.0 1.4 1 1 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase Cons_hypoth95 PF03602.15 ACL94711.1 - 2.2e-06 27.4 0.0 3.2e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 ACL94711.1 - 0.0017 19.0 0.0 0.0036 18.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ACL94711.1 - 0.03 14.9 0.0 0.08 13.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 ACL94711.1 - 0.031 14.0 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 MTS PF05175.14 ACL94711.1 - 0.037 13.6 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_15 PF09445.10 ACL94711.1 - 0.058 13.0 0.0 0.078 12.5 0.0 1.1 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Glyco_tranf_2_3 PF13641.6 ACL94712.2 - 1.4e-25 90.6 0.0 1.9e-25 90.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ACL94712.2 - 1.1e-16 61.3 0.1 1.1e-16 61.3 0.1 1.6 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 ACL94712.2 - 1.1e-13 51.3 0.0 1.7e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ACL94712.2 - 1.3e-10 41.0 0.0 2.1e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 TetR_C_33 PF13305.6 ACL94713.1 - 1.5e-15 57.8 0.0 3e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ACL94713.1 - 6.2e-15 54.7 1.0 9.8e-15 54.1 1.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 ACL94713.1 - 0.028 14.7 0.0 0.071 13.4 0.0 1.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HTH_23 PF13384.6 ACL94713.1 - 0.03 14.1 0.1 0.077 12.8 0.1 1.7 1 0 0 1 1 1 0 Homeodomain-like domain PaREP1 PF05942.11 ACL94713.1 - 0.033 14.1 0.1 2 8.4 0.0 2.3 2 1 0 2 2 2 0 Archaeal PaREP1/PaREP8 family HTH_Tnp_1_2 PF13022.6 ACL94713.1 - 0.042 14.0 0.0 0.071 13.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_7 PF02796.15 ACL94713.1 - 0.16 12.1 0.0 0.44 10.7 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Peripla_BP_2 PF01497.18 ACL94714.1 - 7.4e-13 48.6 0.0 9.7e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein Raf1_HTH PF18579.1 ACL94714.1 - 0.19 11.5 0.0 0.43 10.3 0.0 1.6 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain FecCD PF01032.18 ACL94715.3 - 3.5e-73 246.3 33.4 4.3e-73 246.0 33.4 1.0 1 0 0 1 1 1 1 FecCD transport family ABC_tran PF00005.27 ACL94716.1 - 1.3e-22 80.8 0.0 1.7e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ACL94716.1 - 2.6e-08 34.1 0.9 0.00092 19.1 0.2 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ACL94716.1 - 4.5e-06 26.2 0.2 0.063 12.7 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ACL94716.1 - 0.013 15.8 4.3 0.023 15.1 4.3 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 ACL94716.1 - 0.018 15.6 0.0 0.026 15.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 ACL94716.1 - 0.034 13.5 0.1 0.055 12.9 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI HSM3_N PF18795.1 ACL94716.1 - 0.044 13.2 0.0 0.061 12.7 0.0 1.1 1 0 0 1 1 1 0 DNA mismatch repair protein HSM3, N terminal domain AAA_27 PF13514.6 ACL94716.1 - 0.084 12.4 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ACL94716.1 - 0.091 12.5 0.2 0.17 11.7 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 ACL94716.1 - 0.094 12.3 0.5 0.44 10.1 0.3 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 ACL94716.1 - 0.33 10.6 0.0 1.2 8.7 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain DUF3584 PF12128.8 ACL94716.1 - 0.41 8.1 0.2 0.51 7.8 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SLT PF01464.20 ACL94717.1 - 1e-21 76.8 0.8 2e-21 75.8 0.0 1.9 2 0 0 2 2 2 1 Transglycosylase SLT domain DUF4346 PF14251.6 ACL94717.1 - 0.024 14.7 0.1 0.25 11.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4346) TPR_2 PF07719.17 ACL94717.1 - 2.7 8.3 5.4 3.2 8.1 1.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DHDPS PF00701.22 ACL94718.2 - 4.3e-93 311.2 0.0 4.8e-93 311.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family SmpB PF01668.18 ACL94719.1 - 1.7e-61 206.3 0.1 2e-61 206.1 0.1 1.0 1 0 0 1 1 1 1 SmpB protein DUF2891 PF11199.8 ACL94721.1 - 1.8e-132 441.3 3.0 2e-132 441.1 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2891) DUF979 PF06166.12 ACL94722.1 - 1.8e-120 401.8 20.0 2e-120 401.6 20.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF979) DUF969 PF06149.12 ACL94723.1 - 3e-86 288.3 8.8 3.3e-86 288.2 8.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF969) Na_H_antiport_2 PF13726.6 ACL94723.1 - 0.0027 17.8 2.6 0.0027 17.8 2.6 1.9 1 1 1 2 2 2 1 Na+-H+ antiporter family DUF3098 PF11297.8 ACL94723.1 - 0.23 11.1 3.1 12 5.6 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3098) Aldolase_II PF00596.21 ACL94724.1 - 5.7e-44 150.3 0.6 6.8e-44 150.0 0.6 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain OMP_b-brl PF13505.6 ACL94725.1 - 0.083 13.0 0.0 0.12 12.5 0.0 1.4 1 1 0 1 1 1 0 Outer membrane protein beta-barrel domain HlyD_D23 PF16576.5 ACL94726.1 - 7.4e-29 100.5 0.1 1.1e-28 100.0 0.1 1.2 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 ACL94726.1 - 9.5e-16 58.4 1.1 3.9e-13 50.0 0.0 2.8 3 0 0 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 ACL94726.1 - 3.4e-07 30.0 1.0 2.2e-05 24.2 0.2 2.8 2 0 0 2 2 2 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 ACL94726.1 - 0.012 15.5 0.2 1 9.3 0.0 3.1 3 1 0 3 3 3 0 Biotin-requiring enzyme TarH PF02203.15 ACL94726.1 - 4.6 7.1 9.0 0.22 11.4 3.0 1.7 2 0 0 2 2 2 0 Tar ligand binding domain homologue ACR_tran PF00873.19 ACL94727.1 - 4.4e-286 951.6 6.1 5.1e-286 951.4 6.1 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family SecD_SecF PF02355.16 ACL94727.1 - 1.5e-09 37.5 21.3 2.4e-05 23.8 9.9 2.4 2 0 0 2 2 2 2 Protein export membrane protein MMPL PF03176.15 ACL94727.1 - 4.8e-07 29.0 43.9 1.4e-05 24.3 12.0 2.9 3 0 0 3 3 3 2 MMPL family Transketolase_N PF00456.21 ACL94728.1 - 2.3e-15 56.4 0.0 6.8e-11 41.7 0.0 2.2 2 0 0 2 2 2 2 Transketolase, thiamine diphosphate binding domain PDH_E1_M PF17831.1 ACL94728.1 - 3.4e-12 46.4 0.0 5.1e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Pyruvate dehydrogenase E1 component middle domain DXP_synthase_N PF13292.6 ACL94728.1 - 0.0001 21.6 0.0 0.00027 20.3 0.0 1.6 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 ACL94728.1 - 0.00024 20.8 0.0 0.00039 20.1 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DDE_Tnp_1_2 PF13586.6 ACL94729.1 - 1.6e-20 73.3 0.2 2.4e-20 72.7 0.2 1.3 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 ACL94729.1 - 1.6e-18 67.2 2.7 5.7e-17 62.1 2.7 2.0 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 ACL94729.1 - 1.9e-08 34.5 0.0 2.3e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 ACL94729.1 - 2.1e-05 24.3 0.0 2.4e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease SnoaL_2 PF12680.7 ACL94731.1 - 7e-10 39.5 1.5 7.8e-10 39.3 1.5 1.0 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 ACL94731.1 - 0.00068 19.4 0.2 0.0015 18.3 0.2 1.6 1 1 1 2 2 2 1 SnoaL-like polyketide cyclase SnoaL_3 PF13474.6 ACL94731.1 - 0.0015 18.8 0.3 0.0019 18.5 0.3 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 ACL94731.1 - 0.0051 17.2 0.5 0.0063 16.9 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) NTF2 PF02136.20 ACL94731.1 - 0.016 15.8 0.0 0.019 15.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain SnoaL_2 PF12680.7 ACL94732.1 - 8.8e-24 84.1 1.1 2.2e-13 50.7 0.7 2.2 2 0 0 2 2 2 2 SnoaL-like domain NTF2 PF02136.20 ACL94732.1 - 3.7e-12 46.9 0.0 1.2e-10 42.0 0.0 2.1 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain SnoaL PF07366.12 ACL94732.1 - 3.2e-09 36.6 0.1 3.1e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 SnoaL-like polyketide cyclase SnoaL_3 PF13474.6 ACL94732.1 - 1e-08 35.5 0.0 0.00074 19.8 0.0 2.2 2 0 0 2 2 2 2 SnoaL-like domain DUF4440 PF14534.6 ACL94732.1 - 7.6e-07 29.5 0.8 0.0031 17.9 0.1 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF4440) SnoaL_4 PF13577.6 ACL94732.1 - 0.00074 19.6 0.4 0.029 14.5 0.1 2.5 2 1 0 2 2 2 1 SnoaL-like domain CaMKII_AD PF08332.10 ACL94732.1 - 0.0075 16.4 0.0 0.96 9.6 0.0 2.1 2 0 0 2 2 2 1 Calcium/calmodulin dependent protein kinase II association domain FCD PF07729.12 ACL94732.1 - 0.036 14.5 0.2 0.13 12.7 0.0 2.0 2 0 0 2 2 2 0 FCD domain Cytochrom_C PF00034.21 ACL94733.2 - 3.2e-06 28.2 0.0 9.9e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 Cytochrome c Cytochrome_CBB3 PF13442.6 ACL94733.2 - 0.0074 16.6 0.5 0.052 13.9 0.5 2.2 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Carboxyl_trans PF01039.22 ACL94733.2 - 0.13 10.8 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 Carboxyl transferase domain GcrA PF07750.11 ACL94734.1 - 5.9e-55 186.1 0.3 9.3e-55 185.5 0.3 1.3 1 1 0 1 1 1 1 GcrA cell cycle regulator HTH_50 PF18024.1 ACL94734.1 - 0.0054 16.3 0.1 0.0087 15.6 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 ACL94734.1 - 0.016 15.0 0.1 0.04 13.7 0.1 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_7 PF02796.15 ACL94734.1 - 0.12 12.5 0.0 0.39 10.8 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase MarR PF01047.22 ACL94736.1 - 1.9e-11 43.7 0.1 3.9e-11 42.7 0.1 1.5 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 ACL94736.1 - 1.5e-08 34.4 0.7 2.7e-08 33.6 0.7 1.5 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 ACL94736.1 - 1.1e-07 32.2 0.6 4.3e-07 30.3 0.1 2.0 2 0 0 2 2 2 1 Winged helix DNA-binding domain HxlR PF01638.17 ACL94736.1 - 0.022 14.6 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 HxlR-like helix-turn-helix HTH_Crp_2 PF13545.6 ACL94736.1 - 0.035 14.1 2.6 0.043 13.8 1.4 1.8 1 1 1 2 2 2 0 Crp-like helix-turn-helix domain TMEM132 PF16070.5 ACL94736.1 - 0.067 12.5 0.0 0.079 12.3 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein family 132 RF-1 PF00472.20 ACL94737.1 - 3.5e-23 81.8 0.0 4.5e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 RF-1 domain FUSC PF04632.12 ACL94737.1 - 0.19 10.2 0.1 0.21 10.1 0.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF188 PF02639.14 ACL94738.1 - 7.1e-46 155.1 0.0 8.2e-46 154.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized BCR, YaiI/YqxD family COG1671 PIN_9 PF18477.1 ACL94738.1 - 0.022 15.1 0.0 0.041 14.2 0.0 1.4 1 0 0 1 1 1 0 PIN like domain Aldedh PF00171.22 ACL94739.1 - 4.4e-120 401.3 0.0 5.5e-120 401.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GGDEF_2 PF17853.1 ACL94739.1 - 0.11 12.8 4.3 0.66 10.2 0.3 3.3 2 1 0 3 3 3 0 GGDEF-like domain THF_DHG_CYH_C PF02882.19 ACL94740.1 - 1.2e-67 226.2 2.2 1.2e-67 226.2 2.2 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 ACL94740.1 - 8.7e-38 129.2 0.0 1.3e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 ACL94740.1 - 0.0011 17.9 0.3 0.0019 17.2 0.3 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 ACL94740.1 - 0.056 13.5 0.3 3.4 7.7 0.1 2.3 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 ACL94740.1 - 0.069 13.3 0.1 0.29 11.3 0.1 2.1 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.25 ACL94740.1 - 0.077 12.4 0.1 0.28 10.6 0.1 1.9 2 0 0 2 2 2 0 short chain dehydrogenase DUF4287 PF14117.6 ACL94740.1 - 0.11 12.6 0.1 0.29 11.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4287) Cytochrome_CBB3 PF13442.6 ACL94741.1 - 1e-13 51.4 0.2 1.3e-13 51.1 0.2 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 ACL94741.1 - 0.1 13.7 1.5 0.25 12.5 1.5 1.7 1 1 0 1 1 1 0 Cytochrome c ALO PF04030.14 ACL94742.1 - 7.7e-49 166.9 0.0 9.3e-49 166.6 0.0 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 ACL94742.1 - 8.6e-21 74.1 0.2 8.6e-21 74.1 0.2 1.5 2 0 0 2 2 2 1 FAD binding domain CwsA PF10814.8 ACL94742.1 - 0.0064 16.7 0.7 0.0064 16.7 0.7 2.2 2 0 0 2 2 2 1 Cell wall synthesis protein CwsA Hpt PF01627.23 ACL94743.2 - 0.0001 22.5 0.1 0.00021 21.5 0.1 1.5 1 1 0 1 1 1 1 Hpt domain NAD_kinase PF01513.21 ACL94744.1 - 9.5e-17 61.1 0.0 1.5e-16 60.5 0.0 1.3 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 ACL94744.1 - 0.14 11.8 0.0 0.32 10.6 0.0 1.5 1 1 0 1 1 1 0 Diacylglycerol kinase catalytic domain DUF2336 PF10098.9 ACL94745.1 - 2.2e-63 214.2 13.5 3.3e-63 213.6 13.5 1.2 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2336) FGGY_N PF00370.21 ACL94746.1 - 9.8e-69 231.6 0.0 1.3e-68 231.2 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 ACL94746.1 - 5.1e-44 150.4 5.6 5.1e-44 150.4 5.6 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 ACL94746.1 - 0.038 13.5 1.1 0.72 9.3 0.0 2.5 3 0 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family SGL PF08450.12 ACL94747.1 - 2.2e-44 151.9 0.0 2.8e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 ACL94747.1 - 0.0009 19.2 0.5 8.7 6.6 0.0 4.1 4 0 0 4 4 4 2 NHL repeat PD40 PF07676.12 ACL94747.1 - 0.002 18.0 0.2 4 7.5 0.1 3.1 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Str_synth PF03088.16 ACL94747.1 - 0.0027 17.8 0.0 0.9 9.7 0.0 3.3 3 1 0 3 3 3 1 Strictosidine synthase Arylesterase PF01731.20 ACL94747.1 - 0.021 15.0 0.0 0.057 13.6 0.0 1.7 1 0 0 1 1 1 0 Arylesterase GFO_IDH_MocA PF01408.22 ACL94748.3 - 5.8e-27 94.9 0.0 8.6e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ACL94748.3 - 7.7e-08 32.3 0.0 1.4e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain PT-VENN PF04829.13 ACL94748.3 - 0.1 12.7 0.1 0.27 11.4 0.1 1.7 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Abhydrolase_3 PF07859.13 ACL94749.3 - 5e-14 52.7 0.6 2.6e-11 43.8 0.6 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 ACL94749.3 - 6.5e-08 32.4 0.0 1.3e-07 31.5 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 ACL94749.3 - 1.2e-07 31.4 0.0 0.0038 16.7 0.1 2.4 2 1 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 ACL94749.3 - 2.2e-07 30.1 0.0 2.9e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family AXE1 PF05448.12 ACL94749.3 - 0.024 13.3 0.1 0.059 12.0 0.0 1.6 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 ACL94749.3 - 0.077 12.9 0.0 3.1 7.7 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 ACL94750.1 - 1.1e-33 116.9 0.0 1.6e-33 116.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ACL94750.1 - 2.3e-11 43.4 0.0 6.7e-09 35.4 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ACL94750.1 - 1.4e-09 38.9 4.8 1.9e-09 38.5 4.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 ACL94750.1 - 6.7e-05 21.7 0.0 9.4e-05 21.2 0.0 1.1 1 0 0 1 1 1 1 Ndr family Peptidase_S28 PF05577.12 ACL94750.1 - 0.027 13.3 0.0 0.038 12.8 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Esterase PF00756.20 ACL94750.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Abhydrolase_4 PF08386.10 ACL94750.1 - 0.23 11.6 0.0 0.43 10.7 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein TPR_17 PF13431.6 ACL94751.2 - 0.033 14.6 0.7 0.22 12.0 0.1 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat Abhydrolase_1 PF00561.20 ACL94752.1 - 4.2e-25 88.9 0.0 7.1e-25 88.1 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ACL94752.1 - 5.9e-21 76.1 4.8 8.4e-21 75.6 4.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ACL94752.1 - 1.6e-16 60.4 0.0 2.9e-15 56.2 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 ACL94752.1 - 0.0021 16.8 0.0 0.0043 15.8 0.0 1.4 1 0 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.10 ACL94752.1 - 0.0052 16.9 0.0 0.009 16.1 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein MFS_1 PF07690.16 ACL94753.1 - 5.5e-37 127.5 41.4 5.5e-37 127.5 41.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ACL94753.1 - 4.4e-10 39.0 8.5 4.4e-10 39.0 8.5 2.4 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 ACL94753.1 - 4e-07 28.8 2.4 6.7e-07 28.1 2.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) YesK PF14150.6 ACL94753.1 - 0.084 13.1 4.5 0.094 12.9 1.0 2.8 2 0 0 2 2 2 0 YesK-like protein DUF423 PF04241.15 ACL94754.1 - 7.9e-24 83.7 8.7 1.2e-23 83.1 8.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF423) DUF2627 PF11118.8 ACL94754.1 - 4.4 7.9 10.2 0.88 10.2 0.6 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2627) APH PF01636.23 ACL94756.1 - 3e-33 115.7 5.6 3.7e-33 115.4 5.6 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 ACL94756.1 - 0.014 14.2 0.1 0.02 13.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) DDE_Tnp_1_2 PF13586.6 ACL94759.1 - 1.6e-20 73.3 0.2 2.4e-20 72.7 0.2 1.3 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 ACL94759.1 - 1.6e-18 67.2 2.7 5.7e-17 62.1 2.7 2.0 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 ACL94759.1 - 1.9e-08 34.5 0.0 2.3e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 ACL94759.1 - 2.1e-05 24.3 0.0 2.4e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease TerC PF03741.16 ACL94760.1 - 1.2e-41 142.4 6.6 1.4e-41 142.2 6.6 1.1 1 0 0 1 1 1 1 Integral membrane protein TerC family DUF3318 PF11780.8 ACL94760.1 - 0.0018 18.3 0.6 0.0018 18.3 0.6 2.0 2 1 1 3 3 3 1 Protein of unknown function (DUF3318) FA_desaturase PF00487.24 ACL94760.1 - 0.021 14.7 9.0 0.013 15.3 4.7 2.0 1 1 1 2 2 2 0 Fatty acid desaturase Polysacc_synt_C PF14667.6 ACL94760.1 - 0.025 14.7 1.8 0.025 14.7 1.8 2.4 2 1 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain DUF4131 PF13567.6 ACL94760.1 - 0.031 13.9 6.1 0.25 11.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) SpoU_methylase PF00588.19 ACL94762.1 - 1e-36 126.2 0.0 1.5e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 ACL94762.1 - 8.2e-09 35.6 0.0 1.8e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Methyltrn_RNA_4 PF09936.9 ACL94762.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase GTP_EFTU PF00009.27 ACL94763.1 - 3.9e-59 199.5 0.1 5.1e-59 199.1 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 ACL94763.1 - 1.3e-32 112.4 0.1 2.8e-32 111.4 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 ACL94763.1 - 1.8e-17 63.5 5.5 1.8e-17 63.5 5.5 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ACL94763.1 - 3e-05 24.1 0.0 6.7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 ACL94763.1 - 0.004 16.8 0.5 0.0071 16.0 0.0 1.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 ACL94763.1 - 0.027 14.4 0.1 0.091 12.7 0.0 1.8 1 1 0 1 1 1 0 RsgA GTPase OmdA PF13376.6 ACL94764.2 - 3.1e-18 65.5 0.1 4.9e-18 64.9 0.1 1.3 1 0 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated DUF1801 PF08818.11 ACL94764.2 - 1.6e-05 25.3 0.0 2.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DU1801) FdhD-NarQ PF02634.15 ACL94765.2 - 1.1e-67 228.2 0.1 1.3e-67 228.0 0.1 1.0 1 0 0 1 1 1 1 FdhD/NarQ family Molybdopterin PF00384.22 ACL94766.1 - 9.9e-24 84.1 0.0 1.4e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 ACL94766.1 - 9.5e-11 41.7 0.0 1.9e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain DUF1127 PF06568.11 ACL94766.1 - 0.32 10.7 0.0 0.32 10.7 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1127) Acetyltransf_6 PF13480.7 ACL94767.2 - 6.9e-34 117.0 3.1 6.9e-34 117.0 3.1 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF2807 PF10988.8 ACL94768.1 - 2.4e-17 63.3 26.5 8e-10 38.8 7.9 2.4 1 1 1 2 2 2 2 Putative auto-transporter adhesin, head GIN domain DUF4097 PF13349.6 ACL94768.1 - 3.1e-05 23.4 4.0 0.00013 21.4 4.0 2.1 1 1 0 1 1 1 1 Putative adhesin Peptidase_A24 PF01478.18 ACL94768.1 - 0.93 9.9 3.9 9.7 6.7 0.0 3.3 2 1 0 2 2 2 0 Type IV leader peptidase family Ribosomal_S10 PF00338.22 ACL94770.1 - 3.8e-37 126.5 0.3 4.2e-37 126.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Ribosomal_L3 PF00297.22 ACL94771.1 - 2.5e-18 66.2 6.0 4.2e-15 55.6 3.3 2.3 1 1 1 2 2 2 2 Ribosomal protein L3 Ribosomal_L4 PF00573.22 ACL94772.1 - 9.5e-59 198.3 2.2 1.1e-58 198.1 2.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_L23 PF00276.20 ACL94773.1 - 1.8e-32 111.5 5.0 2e-32 111.4 5.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L23 CCB2_CCB4 PF11152.8 ACL94773.1 - 0.0039 16.5 0.1 0.0044 16.3 0.1 1.0 1 0 0 1 1 1 1 Cofactor assembly of complex C subunit B, CCB2/CCB4 VWA PF00092.28 ACL94773.1 - 0.0088 16.3 1.1 0.011 16.0 1.1 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain Ribosomal_L2_C PF03947.18 ACL94774.1 - 2.5e-56 189.3 3.4 4.1e-56 188.6 3.4 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 ACL94774.1 - 7.8e-28 96.3 1.6 1.6e-27 95.3 0.4 2.2 3 0 0 3 3 3 1 Ribosomal Proteins L2, RNA binding domain DUF4384 PF14326.6 ACL94774.1 - 0.0062 16.6 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4384) PhnA PF03831.14 ACL94774.1 - 0.0076 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 PhnA domain Ribosomal_S19 PF00203.21 ACL94775.1 - 5e-33 112.8 0.0 5.7e-33 112.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_L22 PF00237.19 ACL94776.1 - 9.6e-31 106.1 0.4 1.2e-30 105.8 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_S3_C PF00189.20 ACL94777.1 - 2.6e-39 133.6 1.3 6.1e-39 132.4 1.3 1.6 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 ACL94777.1 - 1.2e-19 69.9 1.3 1.2e-19 69.9 1.3 1.8 2 0 0 2 2 2 1 KH domain Ribosomal_L16 PF00252.18 ACL94778.1 - 6.3e-50 168.6 0.4 7.2e-50 168.4 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_L29 PF00831.23 ACL94779.1 - 1.9e-25 88.6 1.1 2e-25 88.5 1.1 1.0 1 0 0 1 1 1 1 Ribosomal L29 protein HTH_40 PF14493.6 ACL94779.1 - 0.078 13.4 0.2 0.089 13.3 0.2 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain Ribosomal_S17 PF00366.20 ACL94780.1 - 3.9e-26 90.9 2.7 4.4e-26 90.8 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_L14 PF00238.19 ACL94781.1 - 7.8e-55 184.2 3.8 8.6e-55 184.0 3.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DUF730 PF05325.11 ACL94781.1 - 0.043 13.8 0.1 0.077 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF730) ribosomal_L24 PF17136.4 ACL94782.1 - 1.8e-26 92.3 2.0 1.8e-26 92.3 2.0 1.5 2 0 0 2 2 2 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 ACL94782.1 - 3.2e-08 33.2 3.2 3.2e-08 33.2 3.2 2.0 2 0 0 2 2 2 1 KOW motif Ribosomal_L5_C PF00673.21 ACL94783.1 - 3.2e-41 139.4 0.0 5.9e-41 138.5 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 ACL94783.1 - 5e-27 94.0 0.6 1.3e-26 92.7 0.5 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 Taq-exonuc PF09281.10 ACL94783.1 - 0.13 12.3 0.2 0.19 11.7 0.2 1.3 1 0 0 1 1 1 0 Taq polymerase, exonuclease Ribosomal_S14 PF00253.21 ACL94784.1 - 1.9e-24 85.1 0.4 1.3e-23 82.5 0.7 1.9 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e Ribosomal_S8 PF00410.19 ACL94785.1 - 6.5e-45 152.2 0.0 7.2e-45 152.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_L6 PF00347.23 ACL94786.1 - 5.2e-42 142.4 0.6 7.4e-20 71.4 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_L18p PF00861.22 ACL94787.1 - 2.2e-41 140.8 2.2 2.7e-41 140.6 2.2 1.0 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Ribosomal_S5_C PF03719.15 ACL94788.1 - 5.2e-31 105.9 0.2 5.2e-31 105.9 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 ACL94788.1 - 1.5e-28 98.5 2.2 3.1e-28 97.5 2.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_L30 PF00327.20 ACL94789.1 - 8.8e-14 51.1 0.4 9.8e-14 51.0 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L27A PF00828.19 ACL94790.1 - 7.4e-36 123.6 1.7 9.7e-36 123.3 1.7 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A SecY PF00344.20 ACL94791.1 - 4.2e-108 361.2 17.6 5.5e-108 360.8 17.6 1.1 1 0 0 1 1 1 1 SecY translocase ADK PF00406.22 ACL94792.1 - 1e-51 175.0 0.0 1.2e-51 174.8 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 ACL94792.1 - 2.2e-26 92.9 0.1 2.7e-26 92.6 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ACL94792.1 - 3.5e-09 37.0 0.0 4.2e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ACL94792.1 - 4.4e-06 27.3 0.0 6.7e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 ACL94792.1 - 0.019 14.7 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase Ribosomal_S13 PF00416.22 ACL94793.1 - 4.9e-33 114.2 8.8 1.5e-31 109.5 8.8 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 ACL94793.1 - 0.02 13.7 0.0 0.022 13.5 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DNA_pol_lambd_f PF10391.9 ACL94793.1 - 0.072 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda HHH_6 PF14579.6 ACL94793.1 - 0.079 13.2 0.6 0.26 11.6 0.2 1.9 1 1 1 2 2 2 0 Helix-hairpin-helix motif Ribosomal_S11 PF00411.19 ACL94794.1 - 3.7e-52 175.4 1.6 4.3e-52 175.2 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 RNA_pol_A_CTD PF03118.15 ACL94795.1 - 2.2e-25 88.2 0.1 4.1e-25 87.3 0.1 1.4 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain RNA_pol_L PF01193.24 ACL94795.1 - 6.6e-24 83.1 0.0 1e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_A_bac PF01000.26 ACL94795.1 - 5.6e-23 81.5 0.0 1.6e-22 80.0 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain DUF211 PF02680.14 ACL94795.1 - 0.004 17.3 0.1 2.4 8.4 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized ArCR, COG1888 RNA_pol_L_2 PF13656.6 ACL94795.1 - 0.037 13.8 0.1 3.9 7.3 0.0 2.6 3 0 0 3 3 3 0 RNA polymerase Rpb3/Rpb11 dimerisation domain IDH PF03971.14 ACL94795.1 - 0.15 10.5 0.0 0.22 9.9 0.0 1.1 1 0 0 1 1 1 0 Monomeric isocitrate dehydrogenase Ribosomal_L17 PF01196.19 ACL94797.1 - 1e-35 122.5 0.0 1.2e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L17 ABC2_membrane_2 PF12679.7 ACL94799.1 - 8.4e-06 25.3 15.0 1.1e-05 24.9 15.0 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 ACL94799.1 - 0.0012 18.9 6.7 0.015 15.2 4.8 2.3 1 1 1 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 ACL94800.2 - 1.6e-25 90.3 0.0 2.9e-25 89.4 0.0 1.4 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 ACL94800.2 - 3.7e-13 50.0 0.2 6.8e-07 29.4 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ACL94800.2 - 0.00013 22.5 0.1 0.0002 21.9 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ACL94800.2 - 0.0053 16.5 0.0 0.0094 15.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 ACL94800.2 - 0.011 15.4 0.0 0.021 14.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain Phosphodiest PF01663.22 ACL94801.1 - 2.2e-83 280.8 0.1 2.6e-83 280.5 0.1 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 ACL94801.1 - 5.8e-05 22.6 0.0 0.0068 15.8 0.0 2.3 2 0 0 2 2 2 2 Sulfatase PglZ PF08665.12 ACL94801.1 - 0.02 15.0 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 PglZ domain DUF1501 PF07394.12 ACL94801.1 - 0.056 12.5 0.0 0.09 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) GMC_oxred_N PF00732.19 ACL94802.1 - 1.3e-79 267.6 0.0 1.7e-79 267.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ACL94802.1 - 4.5e-37 127.8 0.1 7e-37 127.1 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 ACL94802.1 - 7e-05 22.0 0.0 0.0001 21.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 ACL94802.1 - 8.5e-05 21.8 3.2 0.0011 18.1 3.2 2.2 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 ACL94802.1 - 0.00061 19.1 0.0 0.23 10.6 0.0 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.6 ACL94802.1 - 0.00081 19.6 0.4 0.0038 17.4 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ACL94802.1 - 0.0016 18.1 1.0 0.027 14.1 0.0 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ACL94802.1 - 0.038 12.7 0.1 0.076 11.7 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.14 ACL94802.1 - 0.061 12.5 0.0 0.24 10.6 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ACL94802.1 - 0.21 10.6 0.0 14 4.7 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Glyoxalase PF00903.25 ACL94803.1 - 2.6e-10 40.6 0.0 3.6e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ACL94803.1 - 0.00023 21.9 0.1 0.00037 21.2 0.1 1.3 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 ACL94803.1 - 0.03 14.6 0.1 0.048 13.9 0.1 1.3 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily HTH_5 PF01022.20 ACL94804.1 - 5.2e-14 51.8 0.1 8.5e-14 51.2 0.1 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 ACL94804.1 - 7.1e-12 45.2 5.1 1.1e-11 44.6 4.8 1.5 1 1 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 ACL94804.1 - 6.6e-09 35.5 2.3 1e-08 34.9 2.3 1.3 1 0 0 1 1 1 1 MarR family MarR PF01047.22 ACL94804.1 - 2.5e-06 27.3 0.0 4e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 ACL94804.1 - 1.7e-05 24.3 0.0 2.7e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 ACL94804.1 - 5.8e-05 22.8 1.7 5.8e-05 22.8 1.7 1.7 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_Crp_2 PF13545.6 ACL94804.1 - 6.5e-05 22.8 0.2 9.8e-05 22.3 0.2 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain TrmB PF01978.19 ACL94804.1 - 0.00024 20.9 0.0 0.00035 20.4 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_27 PF13463.6 ACL94804.1 - 0.00084 19.8 0.1 0.0024 18.3 0.0 1.7 1 1 1 2 2 2 1 Winged helix DNA-binding domain HTH_10 PF04967.12 ACL94804.1 - 0.0023 17.7 0.1 0.005 16.6 0.1 1.6 1 0 0 1 1 1 1 HTH DNA binding domain HxlR PF01638.17 ACL94804.1 - 0.0071 16.2 0.0 0.01 15.7 0.0 1.3 1 1 0 1 1 1 1 HxlR-like helix-turn-helix HTH_1 PF00126.27 ACL94804.1 - 0.013 15.4 0.5 0.031 14.2 0.1 1.8 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family LexA_DNA_bind PF01726.16 ACL94804.1 - 0.014 15.1 0.2 0.029 14.1 0.1 1.7 2 0 0 2 2 2 0 LexA DNA binding domain Rrf2 PF02082.20 ACL94804.1 - 0.018 15.4 0.0 0.026 14.9 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator DprA_WH PF17782.1 ACL94804.1 - 0.026 14.6 3.3 0.046 13.8 3.3 1.4 1 0 0 1 1 1 0 DprA winged helix domain HTH_34 PF13601.6 ACL94804.1 - 0.099 12.8 0.0 0.23 11.6 0.0 1.6 2 0 0 2 2 2 0 Winged helix DNA-binding domain Crp PF00325.20 ACL94804.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family Fe_dep_repress PF01325.19 ACL94804.1 - 0.15 12.3 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain MFS_1 PF07690.16 ACL94805.2 - 1.1e-50 172.6 40.0 1.1e-50 172.6 40.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 ACL94805.2 - 2.1e-14 53.2 14.1 4e-09 35.8 5.4 3.0 1 1 1 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 ACL94805.2 - 3e-11 42.9 19.6 2.1e-10 40.1 5.7 3.2 2 1 1 3 3 3 3 Sugar (and other) transporter TRI12 PF06609.13 ACL94805.2 - 1.1e-05 24.0 0.8 2e-05 23.2 0.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 ACL94805.2 - 0.0032 16.8 7.4 0.0032 16.8 7.4 2.2 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB Folate_carrier PF01770.18 ACL94805.2 - 0.1 11.3 0.0 0.23 10.2 0.0 1.5 2 0 0 2 2 2 0 Reduced folate carrier OATP PF03137.20 ACL94805.2 - 5.5 5.2 6.7 1.5 7.0 0.9 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Trypsin_2 PF13365.6 ACL94806.1 - 9.2e-31 107.8 0.6 1.7e-30 106.9 0.6 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 ACL94806.1 - 3.9e-21 75.2 0.1 9.3e-14 51.5 0.0 3.1 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 ACL94806.1 - 1.5e-17 63.2 2.1 3.1e-10 39.8 0.2 3.3 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 ACL94806.1 - 3.3e-15 56.2 1.2 1.1e-08 35.3 0.2 3.7 3 0 0 3 3 3 2 PDZ domain Trypsin PF00089.26 ACL94806.1 - 3.5e-12 46.6 0.0 6.5e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.6 ACL94806.1 - 1.8e-06 27.8 0.1 0.075 13.0 0.0 2.7 2 0 0 2 2 2 2 Tricorn protease PDZ domain Peptidase_S46 PF10459.9 ACL94806.1 - 0.0019 16.9 3.0 0.3 9.7 0.2 2.2 2 0 0 2 2 2 2 Peptidase S46 DUF3701 PF12482.8 ACL94806.1 - 0.013 15.5 0.1 0.028 14.5 0.1 1.5 1 0 0 1 1 1 0 Phage integrase protein PDZ_1 PF12812.7 ACL94806.1 - 0.014 15.4 0.0 9.4 6.3 0.0 2.5 2 0 0 2 2 2 0 PDZ-like domain MgsA_C PF12002.8 ACL94807.1 - 3.6e-68 228.7 0.0 5.1e-68 228.3 0.0 1.2 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 ACL94807.1 - 3.7e-19 68.8 0.0 1e-18 67.4 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 ACL94807.1 - 1.5e-14 54.5 0.0 2.7e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 ACL94807.1 - 9.1e-12 45.0 0.0 1.9e-11 44.0 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 ACL94807.1 - 6e-07 29.5 0.1 3.5e-06 27.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 ACL94807.1 - 4.5e-06 26.5 0.0 0.0005 19.8 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 ACL94807.1 - 1.7e-05 24.9 0.0 3.2e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_18 PF13238.6 ACL94807.1 - 5.7e-05 23.7 0.0 0.00013 22.5 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.6 ACL94807.1 - 7.2e-05 23.1 0.3 0.026 14.8 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 ACL94807.1 - 7.9e-05 23.1 2.3 0.011 16.1 0.0 3.1 1 1 2 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.21 ACL94807.1 - 0.0005 19.5 0.2 0.019 14.4 0.1 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 ACL94807.1 - 0.00084 19.6 0.0 0.0025 18.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 ACL94807.1 - 0.00092 19.0 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 ACL94807.1 - 0.00097 19.3 0.0 0.002 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 ACL94807.1 - 0.0012 18.7 0.0 0.0041 17.0 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 ACL94807.1 - 0.0016 18.2 0.2 0.03 14.0 0.2 2.3 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 ACL94807.1 - 0.0021 18.2 0.1 0.037 14.2 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase ResIII PF04851.15 ACL94807.1 - 0.0028 17.7 0.1 0.91 9.5 0.0 2.3 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit Cytidylate_kin PF02224.18 ACL94807.1 - 0.0093 15.7 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase AAA_14 PF13173.6 ACL94807.1 - 0.012 15.6 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ACL94807.1 - 0.013 15.2 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 ACL94807.1 - 0.017 15.5 0.2 0.44 10.9 0.1 2.3 1 1 1 2 2 2 0 AAA domain Rad17 PF03215.15 ACL94807.1 - 0.026 14.5 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain TIP49 PF06068.13 ACL94807.1 - 0.033 13.4 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_17 PF13207.6 ACL94807.1 - 0.038 14.4 0.0 0.072 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 ACL94807.1 - 0.06 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Alpha-E PF04168.12 ACL94807.1 - 0.069 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. AAA_25 PF13481.6 ACL94807.1 - 0.075 12.6 0.2 0.27 10.8 0.0 2.2 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 ACL94807.1 - 0.092 13.1 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.6 ACL94807.1 - 0.17 11.7 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 ACL94807.1 - 0.17 11.3 0.0 1.4 8.3 0.0 2.1 1 1 1 2 2 2 0 Bacterial TniB protein AAA_2 PF07724.14 ACL94807.1 - 0.19 11.8 0.0 0.39 10.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) PseudoU_synth_2 PF00849.22 ACL94808.1 - 9.2e-33 113.6 0.0 1.1e-32 113.3 0.0 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase DNA_pol3_chi PF04364.13 ACL94808.1 - 0.1 12.7 0.4 2.1 8.5 0.1 2.7 1 1 0 2 2 2 0 DNA polymerase III chi subunit, HolC adh_short_C2 PF13561.6 ACL94810.1 - 4.5e-58 196.6 2.1 5.4e-58 196.3 2.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ACL94810.1 - 1.7e-54 184.3 1.5 2.1e-54 183.9 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ACL94810.1 - 3.8e-11 43.2 1.7 5.3e-11 42.8 1.7 1.1 1 0 0 1 1 1 1 KR domain Sulf_coat_C PF12193.8 ACL94810.1 - 0.016 15.3 0.8 0.087 12.9 0.1 2.5 3 0 0 3 3 3 0 Sulfolobus virus coat protein C terminal DFP PF04127.15 ACL94810.1 - 0.027 14.3 1.1 0.027 14.3 1.1 1.8 2 1 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein 3HCDH_N PF02737.18 ACL94810.1 - 0.18 11.7 0.6 0.28 11.0 0.6 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain OmpW PF03922.14 ACL94811.1 - 1.3e-65 220.8 0.0 1.6e-65 220.6 0.0 1.0 1 0 0 1 1 1 1 OmpW family OMP_b-brl PF13505.6 ACL94811.1 - 6.4e-11 42.7 0.1 8.6e-11 42.3 0.1 1.2 1 0 0 1 1 1 1 Outer membrane protein beta-barrel domain Opacity PF02462.15 ACL94811.1 - 0.037 14.1 0.3 0.065 13.3 0.1 1.7 2 1 0 2 2 2 0 Opacity family porin protein P5CR_dimer PF14748.6 ACL94811.1 - 1.1 9.5 6.1 4.5 7.6 0.5 2.3 2 0 0 2 2 2 0 Pyrroline-5-carboxylate reductase dimerisation DUF2490 PF10677.9 ACL94812.3 - 4e-42 144.3 0.0 4.7e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2490) SnoaL_3 PF13474.6 ACL94813.3 - 0.0057 16.9 0.5 0.036 14.3 0.1 2.1 2 1 0 2 2 2 1 SnoaL-like domain DUF4440 PF14534.6 ACL94813.3 - 0.0081 16.6 0.4 0.017 15.5 0.3 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) BetaGal_dom3 PF13363.6 ACL94813.3 - 0.045 13.3 0.6 0.082 12.5 0.6 1.4 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 DUF4096 PF13340.6 ACL94814.1 - 1.4e-25 89.3 3.5 1.9e-25 88.9 3.5 1.2 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) DDE_Tnp_1_2 PF13586.6 ACL94815.1 - 1.8e-17 63.5 0.2 2.3e-17 63.2 0.2 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 ACL94815.1 - 4.4e-11 42.8 0.4 5.9e-10 39.2 0.4 1.9 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 ACL94815.1 - 2e-05 24.3 0.0 2.3e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_3 PF13612.6 ACL94815.1 - 4.2e-05 23.6 0.0 5.3e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_5 PF13546.6 ACL94815.1 - 0.007 15.7 0.1 0.0081 15.5 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease BT1 PF03092.16 ACL94815.1 - 0.047 11.9 0.0 0.05 11.8 0.0 1.0 1 0 0 1 1 1 0 BT1 family Trans_reg_C PF00486.28 ACL94816.1 - 5.2e-25 87.3 0.0 9.4e-25 86.5 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 ACL94816.1 - 6.8e-24 84.2 0.1 1e-23 83.6 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Isochorismatase PF00857.20 ACL94816.1 - 0.064 13.4 0.0 0.55 10.4 0.0 2.0 2 0 0 2 2 2 0 Isochorismatase family HATPase_c PF02518.26 ACL94817.2 - 2.4e-19 69.9 0.0 4.3e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ACL94817.2 - 3.1e-14 52.7 3.4 1.1e-13 50.9 1.1 3.1 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 ACL94817.2 - 4.6e-06 26.9 0.6 3.2e-05 24.2 0.0 2.7 2 0 0 2 2 2 1 HAMP domain Cortex-I_coil PF09304.10 ACL94817.2 - 0.024 14.8 2.7 0.063 13.5 2.7 1.7 1 0 0 1 1 1 0 Cortexillin I, coiled coil ALIX_LYPXL_bnd PF13949.6 ACL94817.2 - 0.6 9.3 5.3 2.4 7.4 2.2 2.3 2 1 0 2 2 2 0 ALIX V-shaped domain binding to HIV Phytase PF02333.15 ACL94818.2 - 7.3e-139 462.9 0.1 7.2e-98 328.0 0.2 2.0 1 1 1 2 2 2 2 Phytase Lactonase PF10282.9 ACL94818.2 - 0.046 13.0 0.0 15 4.7 0.0 3.7 4 0 0 4 4 4 0 Lactonase, 7-bladed beta-propeller GFO_IDH_MocA PF01408.22 ACL94819.1 - 2.5e-17 63.8 0.0 4.4e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ACL94819.1 - 4.2e-08 33.2 0.0 9.9e-08 32.0 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain DapB_N PF01113.20 ACL94819.1 - 0.054 13.6 0.1 0.1 12.7 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Gp_dh_N PF00044.24 ACL94819.1 - 0.065 13.6 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain SIS PF01380.22 ACL94820.1 - 2.7e-22 79.0 0.2 4.1e-22 78.4 0.2 1.2 1 0 0 1 1 1 1 SIS domain HTH_6 PF01418.17 ACL94820.1 - 2.8e-08 33.6 0.6 1.1e-07 31.7 0.0 2.3 3 0 0 3 3 3 1 Helix-turn-helix domain, rpiR family SIS_2 PF13580.6 ACL94820.1 - 0.0015 18.6 0.1 0.0048 16.9 0.0 1.9 1 1 0 1 1 1 1 SIS domain B12-binding PF02310.19 ACL94820.1 - 0.094 12.8 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 B12 binding domain DUF2090 PF09863.9 ACL94821.1 - 8.3e-131 435.6 0.1 1.1e-130 435.3 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2090) PfkB PF00294.24 ACL94821.1 - 4.4e-51 174.0 0.0 8.1e-51 173.1 0.0 1.4 1 1 0 1 1 1 1 pfkB family carbohydrate kinase TPP_enzyme_N PF02776.18 ACL94822.1 - 4.7e-40 137.0 1.0 1.5e-39 135.3 0.7 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 ACL94822.1 - 4.8e-37 126.8 1.0 9.6e-37 125.8 1.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 ACL94822.1 - 7e-35 120.1 0.6 1.7e-34 118.8 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.16 ACL94822.1 - 0.057 13.2 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit AP_endonuc_2 PF01261.24 ACL94823.1 - 5.2e-27 94.7 0.3 1.4e-26 93.3 0.1 1.7 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel KduI PF04962.12 ACL94824.1 - 9.2e-108 359.5 0.0 1e-107 359.3 0.0 1.0 1 0 0 1 1 1 1 KduI/IolB family Aldedh PF00171.22 ACL94825.1 - 3.4e-137 457.7 0.0 3.8e-137 457.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 ACL94825.1 - 0.0002 20.5 0.0 0.00025 20.2 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) PepSY PF03413.19 ACL94826.2 - 2.5e-06 28.0 0.0 3.7e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain PepSY_2 PF13670.6 ACL94826.2 - 2.9e-06 27.2 0.6 2.2e-05 24.4 0.6 1.9 1 1 0 1 1 1 1 Peptidase propeptide and YPEB domain Response_reg PF00072.24 ACL94827.1 - 5.5e-22 78.1 0.0 7.8e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 ACL94827.1 - 1.2e-18 66.9 0.0 1.9e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal MarR_2 PF12802.7 ACL94827.1 - 0.0011 18.8 2.9 0.0023 17.8 0.1 2.6 3 0 0 3 3 3 1 MarR family HTH_11 PF08279.12 ACL94827.1 - 0.067 13.1 0.0 0.64 10.0 0.0 2.5 2 1 0 2 2 2 0 HTH domain HTH_20 PF12840.7 ACL94827.1 - 0.17 12.0 1.7 0.56 10.3 0.5 2.5 3 1 0 3 3 3 0 Helix-turn-helix domain HATPase_c PF02518.26 ACL94828.1 - 2.8e-06 27.8 0.0 4.7e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 ACL94828.1 - 0.00031 20.7 0.2 0.00031 20.7 0.2 1.9 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain HisKA PF00512.25 ACL94828.1 - 0.074 13.1 2.2 0.21 11.6 0.6 2.6 2 1 0 2 2 2 0 His Kinase A (phospho-acceptor) domain TPPK_C PF12555.8 ACL94828.1 - 0.19 11.8 9.7 0.4 10.8 0.6 2.8 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Dus PF01207.17 ACL94829.1 - 6.1e-78 262.0 0.0 7.2e-78 261.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 ACL94829.1 - 0.042 13.3 0.0 0.1 12.1 0.0 1.7 1 1 0 1 1 1 0 Histidine biosynthesis protein gag-asp_proteas PF13975.6 ACL94830.1 - 3.9e-24 85.0 0.3 6.3e-24 84.4 0.3 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 ACL94830.1 - 2.3e-20 73.0 0.4 3.9e-20 72.3 0.4 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 ACL94830.1 - 0.047 13.5 0.0 0.066 13.0 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease RVP PF00077.20 ACL94830.1 - 0.17 12.2 0.1 0.66 10.3 0.1 2.1 1 1 1 2 2 2 0 Retroviral aspartyl protease Esterase_phd PF10503.9 ACL94830.1 - 0.32 10.5 7.0 0.042 13.3 3.1 1.4 2 0 0 2 2 2 0 Esterase PHB depolymerase DUF1289 PF06945.13 ACL94831.1 - 1.5e-20 72.7 0.2 1.8e-20 72.4 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1289) DBI_PRT PF02277.17 ACL94832.1 - 3.1e-44 151.5 14.3 9.4e-44 150.0 14.3 1.6 1 1 0 1 1 1 1 Phosphoribosyltransferase Acyl-CoA_dh_N PF02771.16 ACL94833.1 - 3.4e-24 85.7 0.0 7.2e-24 84.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 ACL94833.1 - 4.5e-22 78.9 0.0 6.2e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ACL94833.1 - 7.2e-18 64.6 0.0 1.2e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 ACL94834.2 - 6.6e-23 81.6 4.2 9.6e-23 81.1 4.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ACL94834.2 - 1.6e-17 63.5 0.1 4.1e-17 62.2 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ACL94834.2 - 6.8e-12 46.1 1.0 1.4e-11 45.0 0.0 2.1 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ACL94834.2 - 0.00059 20.1 1.9 0.0011 19.3 1.9 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Lysine_decarbox PF03641.14 ACL94837.1 - 1.5e-39 135.1 0.0 1.9e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 ACL94837.1 - 1.3e-17 63.9 0.0 1.6e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 SLOG cluster4 family Big_6 PF17936.1 ACL94838.1 - 1e-07 32.1 0.0 0.0041 17.4 0.0 2.4 2 0 0 2 2 2 2 Bacterial Ig domain ABC_tran PF00005.27 ACL94839.3 - 2.4e-32 112.3 0.0 5.4e-32 111.2 0.0 1.6 2 0 0 2 2 1 1 ABC transporter ABC_membrane PF00664.23 ACL94839.3 - 2.7e-29 102.7 1.7 3.3e-29 102.4 1.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_16 PF13191.6 ACL94839.3 - 1.8e-07 31.7 0.7 1.8e-07 31.7 0.7 2.1 3 0 0 3 3 2 1 AAA ATPase domain SMC_N PF02463.19 ACL94839.3 - 2.1e-05 24.1 0.1 0.0011 18.4 0.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ACL94839.3 - 0.00069 19.9 0.1 0.0091 16.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ACL94839.3 - 0.0013 18.4 2.3 0.0057 16.4 2.3 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 ACL94839.3 - 0.0037 17.7 0.2 0.094 13.1 0.1 2.6 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 ACL94839.3 - 0.0092 14.8 0.2 0.049 12.4 0.0 1.9 2 0 0 2 2 2 1 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 ACL94839.3 - 0.0097 15.8 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Zeta_toxin PF06414.12 ACL94839.3 - 0.01 15.1 0.1 0.025 13.8 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_29 PF13555.6 ACL94839.3 - 0.013 15.3 0.0 0.036 13.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 ACL94839.3 - 0.044 13.7 0.0 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 NTPase AAA_33 PF13671.6 ACL94839.3 - 0.046 13.9 0.7 0.21 11.7 0.7 2.1 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 ACL94839.3 - 0.051 13.6 0.1 0.32 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 ACL94839.3 - 0.077 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 ACL94839.3 - 0.13 12.0 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ACL94839.3 - 0.14 12.7 0.0 0.24 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_membrane_3 PF13748.6 ACL94839.3 - 0.19 11.0 2.4 0.41 9.9 2.3 1.7 1 1 0 1 1 1 0 ABC transporter transmembrane region AAA_7 PF12775.7 ACL94839.3 - 0.26 10.8 0.0 0.44 10.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SbcCD_C PF13558.6 ACL94839.3 - 0.74 10.1 4.2 2.3 8.5 0.7 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Glyoxalase PF00903.25 ACL94840.2 - 1.3e-14 54.5 0.0 1.8e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ACL94840.2 - 7.6e-12 45.5 0.0 5.7e-11 42.7 0.0 1.9 1 1 1 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ACL94840.2 - 1.4e-05 25.8 0.0 1.8e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 ACL94840.2 - 0.09 12.9 0.0 0.26 11.4 0.0 1.8 1 1 0 1 1 1 0 Glyoxalase-like domain Glyoxalase_2 PF12681.7 ACL94840.2 - 0.22 11.4 0.0 0.56 10.1 0.0 1.7 1 1 0 1 1 1 0 Glyoxalase-like domain GST_N PF02798.20 ACL94841.2 - 2.5e-12 46.9 0.0 5.5e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ACL94841.2 - 5.2e-11 42.8 0.0 9.7e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ACL94841.2 - 9.4e-09 35.5 0.0 1.8e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ACL94841.2 - 6.4e-08 32.7 0.0 1.6e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ACL94841.2 - 1.8e-05 24.7 0.4 4.3e-05 23.4 0.1 1.7 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ACL94841.2 - 0.0031 17.7 0.0 0.0046 17.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain HemY_N PF07219.13 ACL94842.2 - 9.7e-06 25.7 0.7 1e-05 25.6 0.7 1.0 1 0 0 1 1 1 1 HemY protein N-terminus LPG_synthase_TM PF03706.13 ACL94842.2 - 0.0099 15.4 0.5 0.0099 15.4 0.5 1.0 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region TMEM240 PF15207.6 ACL94842.2 - 0.023 14.4 0.1 0.026 14.2 0.1 1.1 1 0 0 1 1 1 0 TMEM240 family PCMT PF01135.19 ACL94843.1 - 2.2e-05 24.3 0.0 0.14 11.9 0.1 2.1 1 1 1 2 2 2 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 ACL94843.1 - 0.024 15.3 0.0 0.58 10.9 0.0 2.5 3 0 0 3 3 3 0 Methyltransferase domain OEP PF02321.18 ACL94844.2 - 9.4e-64 214.7 30.2 1.7e-32 112.7 10.3 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein BLOC1S3 PF15753.5 ACL94844.2 - 0.25 11.5 3.3 0.67 10.1 0.2 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 DUF2497 PF10691.9 ACL94845.1 - 4.7e-24 84.6 1.3 5.9e-24 84.3 0.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2497) DUF2428 PF10350.9 ACL94845.1 - 0.23 10.7 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) tRNA-synt_1 PF00133.22 ACL94846.1 - 1.5e-207 690.6 0.1 1.7e-206 687.1 0.1 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 ACL94846.1 - 2.4e-40 138.0 0.0 6e-40 136.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Val_tRNA-synt_C PF10458.9 ACL94846.1 - 7.9e-19 67.7 7.3 2e-18 66.4 7.3 1.8 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1g PF09334.11 ACL94846.1 - 2.2e-18 66.2 1.9 3.3e-08 32.7 0.7 3.7 3 1 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 ACL94846.1 - 4.1e-06 26.4 0.1 0.00018 21.1 0.0 2.5 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1f PF01921.18 ACL94846.1 - 0.034 13.1 0.0 0.059 12.3 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) ABC_tran_CTD PF16326.5 ACL94846.1 - 0.2 11.9 3.4 0.84 9.9 3.4 2.0 1 0 0 1 1 1 0 ABC transporter C-terminal domain tRNA-synt_1b PF00579.25 ACL94846.1 - 3.7 6.8 4.6 2.2 7.5 0.0 2.4 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) AMP-binding PF00501.28 ACL94847.1 - 1.9e-97 326.5 0.0 2.6e-97 326.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ACL94847.1 - 5.8e-20 72.0 0.9 1.7e-19 70.5 0.9 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1801 PF08818.11 ACL94848.1 - 1e-11 45.1 0.0 1.6e-11 44.5 0.0 1.3 2 0 0 2 2 2 1 Domain of unknown function (DU1801) Amidase PF01425.21 ACL94849.1 - 2.5e-83 280.6 0.2 2.9e-83 280.3 0.2 1.1 1 0 0 1 1 1 1 Amidase FtsJ PF01728.19 ACL94850.2 - 1e-17 64.8 0.0 1.2e-17 64.6 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase S4 PF01479.25 ACL94850.2 - 1.4e-10 40.7 0.6 3.2e-10 39.6 0.6 1.6 1 0 0 1 1 1 1 S4 domain Rick_17kDa_Anti PF05433.15 ACL94851.2 - 0.001 18.9 27.7 0.001 18.9 27.7 1.9 2 0 0 2 2 2 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 ACL94851.2 - 0.065 13.2 23.6 0.16 12.0 23.5 1.7 1 1 0 1 1 1 0 Glycine zipper TraT PF05818.12 ACL94851.2 - 0.066 12.9 7.8 0.15 11.7 7.8 1.5 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Gly-zipper_YMGG PF13441.6 ACL94851.2 - 0.53 10.1 27.7 0.99 9.2 27.4 1.7 1 1 0 1 1 1 0 YMGG-like Gly-zipper MccV PF17508.2 ACL94851.2 - 9.3 6.9 9.4 2.1 8.9 4.8 2.2 2 0 0 2 2 2 0 Microcin V bacteriocin tRNA_U5-meth_tr PF05958.11 ACL94852.1 - 2.1e-18 66.4 0.0 7.7e-17 61.3 0.0 2.1 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase TRAM PF01938.20 ACL94852.1 - 0.00018 21.5 0.0 0.00045 20.2 0.0 1.8 1 0 0 1 1 1 1 TRAM domain Met_10 PF02475.16 ACL94852.1 - 0.00058 19.7 0.4 0.043 13.6 0.0 2.2 1 1 1 2 2 2 2 Met-10+ like-protein MTS PF05175.14 ACL94852.1 - 0.0041 16.7 0.0 0.0066 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 ACL94852.1 - 0.005 17.5 0.0 0.021 15.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ACL94853.1 - 1.5e-18 67.2 0.0 3.8e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ACL94853.1 - 7.1e-18 65.1 0.0 1.4e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ACL94853.1 - 2.3e-13 50.3 0.0 3.2e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ACL94853.1 - 1.5e-11 44.1 0.0 2.5e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ACL94853.1 - 3.1e-11 43.9 0.0 5.5e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ACL94853.1 - 8.7e-11 41.8 0.0 1.2e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 ACL94853.1 - 0.00066 19.0 0.0 0.0013 18.1 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 ACL94853.1 - 0.0034 17.0 0.0 0.01 15.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 ACL94853.1 - 0.0039 16.7 0.0 0.054 13.0 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_9 PF08003.11 ACL94853.1 - 0.018 14.0 0.0 0.024 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) CMAS PF02353.20 ACL94853.1 - 0.038 13.3 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase TPMT PF05724.11 ACL94853.1 - 0.073 12.7 0.0 1.4 8.5 0.0 2.1 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Acyl_transf_3 PF01757.22 ACL94854.1 - 1.2e-19 70.5 40.0 1.5e-19 70.3 40.0 1.1 1 0 0 1 1 1 1 Acyltransferase family Sigma70_r2 PF04542.14 ACL94855.1 - 8.8e-14 51.0 0.3 2.6e-13 49.5 0.3 1.9 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 ACL94855.1 - 8e-10 38.2 0.4 2.5e-09 36.7 0.4 2.0 1 0 0 1 1 1 1 Sigma-70, region 4 YCII PF03795.14 ACL94855.1 - 5.2e-05 23.6 0.2 0.00023 21.5 0.0 2.3 2 0 0 2 2 2 1 YCII-related domain Sigma70_ECF PF07638.11 ACL94855.1 - 0.0021 18.0 0.4 0.0067 16.3 0.4 1.9 1 1 0 1 1 1 1 ECF sigma factor TPR_2 PF07719.17 ACL94855.1 - 0.005 16.9 7.1 0.0057 16.7 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Sigma70_r4 PF04545.16 ACL94855.1 - 0.0099 15.4 0.2 0.026 14.0 0.2 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 TPR_14 PF13428.6 ACL94855.1 - 0.027 15.3 1.1 0.027 15.3 1.1 6.1 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 ACL94855.1 - 0.042 13.7 1.4 0.44 10.4 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat GerE PF00196.19 ACL94855.1 - 0.1 12.2 0.1 0.28 10.7 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family TPR_12 PF13424.6 ACL94855.1 - 1.3 9.4 8.8 0.62 10.4 0.6 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Radical_SAM PF04055.21 ACL94856.2 - 8.4e-19 68.6 0.0 1.6e-18 67.6 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily DUF1848 PF08902.11 ACL94856.2 - 0.012 15.3 1.3 0.087 12.5 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1848) DUF5131 PF07505.11 ACL94856.2 - 0.035 13.6 0.0 0.054 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF5131) Fer4_12 PF13353.6 ACL94856.2 - 0.13 12.5 0.0 0.21 11.8 0.0 1.2 1 0 0 1 1 1 0 4Fe-4S single cluster domain Polysacc_deac_1 PF01522.21 ACL94856.2 - 0.15 12.0 0.0 0.54 10.2 0.0 1.9 1 1 1 2 2 2 0 Polysaccharide deacetylase SLT PF01464.20 ACL94858.2 - 1.3e-22 79.7 0.0 6.4e-22 77.4 0.0 2.0 2 0 0 2 2 2 1 Transglycosylase SLT domain TPR_6 PF13174.6 ACL94858.2 - 0.3 11.8 0.3 0.3 11.8 0.3 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 ACL94858.2 - 1 9.9 15.2 0.13 12.8 3.8 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 ACL94858.2 - 1.3 9.4 24.7 3.6 7.9 0.2 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat UDG PF03167.19 ACL94859.1 - 5.2e-41 140.2 0.0 6.8e-41 139.8 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily ETF_QO PF05187.13 ACL94860.1 - 2.1e-49 166.0 0.0 3.3e-49 165.3 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 ACL94860.1 - 2e-11 44.1 1.9 4.7e-05 23.1 2.5 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 ACL94860.1 - 6.3e-08 32.2 0.0 0.00013 21.3 0.2 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.6 ACL94860.1 - 8.1e-08 32.4 0.3 9.6e-07 28.9 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ACL94860.1 - 2.4e-07 30.2 2.7 0.00023 20.4 3.6 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 ACL94860.1 - 3.1e-06 26.6 0.2 1.6e-05 24.3 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ACL94860.1 - 2e-05 24.0 0.1 0.0002 20.8 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ACL94860.1 - 8e-05 21.5 1.6 0.00012 20.9 1.6 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 ACL94860.1 - 0.0002 20.8 0.1 0.00026 20.5 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ACL94860.1 - 0.00036 19.7 1.0 0.00053 19.1 1.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 ACL94860.1 - 0.00038 21.0 0.3 1.2 9.7 0.5 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ACL94860.1 - 0.00081 19.4 0.2 0.0017 18.4 0.2 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 ACL94860.1 - 0.0019 17.5 1.2 0.003 16.8 1.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ACL94860.1 - 0.021 13.9 1.6 0.03 13.4 1.6 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 ACL94860.1 - 0.032 13.1 1.0 0.052 12.4 0.7 1.4 2 0 0 2 2 2 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 ACL94860.1 - 0.088 12.1 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Fer4_7 PF12838.7 ACL94860.1 - 0.11 13.0 0.6 0.24 12.0 0.6 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 ACL94860.1 - 0.12 12.5 0.8 0.27 11.4 0.8 1.5 1 0 0 1 1 1 0 4Fe-4S binding domain K_oxygenase PF13434.6 ACL94860.1 - 0.17 11.0 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) TPR_2 PF07719.17 ACL94861.1 - 1.3e-32 109.2 30.1 6.3e-06 25.9 0.0 11.3 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_16 PF13432.6 ACL94861.1 - 1.1e-30 105.9 67.0 3.6e-09 37.1 0.1 8.7 6 2 4 10 10 10 8 Tetratricopeptide repeat TPR_14 PF13428.6 ACL94861.1 - 1.3e-26 91.0 54.2 3.9e-05 24.1 0.0 11.7 4 4 7 11 11 11 7 Tetratricopeptide repeat TPR_1 PF00515.28 ACL94861.1 - 2.7e-24 83.9 14.8 0.0002 21.0 0.0 9.5 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 ACL94861.1 - 4e-20 72.1 42.6 1e-06 29.1 0.0 8.5 7 2 2 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 ACL94861.1 - 1.4e-17 62.3 11.7 0.0013 18.8 0.0 9.8 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_9 PF13371.6 ACL94861.1 - 1.5e-17 63.5 30.5 5.1e-06 26.5 3.3 5.9 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 ACL94861.1 - 9.6e-17 60.4 12.0 7.7e-09 35.1 0.1 6.5 8 0 0 8 8 8 3 TPR repeat TPR_7 PF13176.6 ACL94861.1 - 1e-16 59.6 18.0 3.4e-05 23.5 0.0 9.9 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 ACL94861.1 - 7e-16 58.3 34.8 0.0011 19.2 0.1 8.7 7 3 1 9 9 8 4 Tetratricopeptide repeat TPR_6 PF13174.6 ACL94861.1 - 4.1e-11 42.8 27.0 0.042 14.5 0.0 10.0 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_15 PF13429.6 ACL94861.1 - 4.7e-11 42.4 24.6 1.3e-08 34.4 1.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ACL94861.1 - 5.9e-08 32.8 2.5 0.0019 18.4 0.0 5.1 4 2 3 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 ACL94861.1 - 1.7e-07 31.2 0.3 0.029 14.5 0.0 5.9 6 0 0 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 ACL94861.1 - 6.7e-07 29.0 27.3 1.5 8.8 1.3 9.0 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_17 PF13431.6 ACL94861.1 - 8.1e-05 22.7 15.9 2.5 8.7 0.0 9.2 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_20 PF14561.6 ACL94861.1 - 0.00083 19.6 14.7 0.11 12.8 2.3 4.9 4 2 2 6 6 6 2 Tetratricopeptide repeat NARP1 PF12569.8 ACL94861.1 - 0.11 11.4 0.0 1 8.2 0.0 2.3 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 TPR_5 PF12688.7 ACL94861.1 - 1.4 9.2 8.8 0.046 14.0 1.2 2.5 3 1 1 4 4 3 0 Tetratrico peptide repeat GHMP_kinases_C PF08544.13 ACL94862.1 - 4.5e-08 33.4 0.1 1.2e-07 32.0 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 ACL94862.1 - 0.00047 20.3 2.0 0.00047 20.3 2.0 1.8 2 0 0 2 2 2 1 GHMP kinases N terminal domain Pro_isomerase PF00160.21 ACL94863.1 - 4.2e-30 105.1 0.0 5.3e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ammonium_transp PF00909.21 ACL94864.1 - 4.9e-108 361.4 32.1 5.7e-108 361.2 32.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DEC-1_N PF04625.13 ACL94864.1 - 0.075 12.0 8.2 0.11 11.5 8.2 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region P-II PF00543.22 ACL94865.1 - 1.9e-40 137.6 1.8 2.1e-40 137.4 1.8 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II DUF2344 PF10105.9 ACL94865.1 - 0.0015 18.4 0.0 0.0017 18.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2344) CdAMP_rec PF06153.11 ACL94865.1 - 0.016 15.4 0.4 0.16 12.1 0.4 2.1 1 1 0 1 1 1 0 Cyclic-di-AMP receptor tRNA-synt_2e PF02091.15 ACL94868.1 - 3.5e-139 462.8 0.0 3.9e-139 462.6 0.0 1.0 1 0 0 1 1 1 1 Glycyl-tRNA synthetase alpha subunit N-glycanase_C PF09113.10 ACL94868.1 - 0.0019 18.0 0.4 0.0035 17.1 0.4 1.4 1 0 0 1 1 1 1 Peptide-N-glycosidase F, C terminal tRNA_synt_2f PF02092.17 ACL94869.1 - 2.6e-195 650.4 0.0 3e-195 650.2 0.0 1.0 1 0 0 1 1 1 1 Glycyl-tRNA synthetase beta subunit DALR_1 PF05746.15 ACL94869.1 - 0.00079 19.6 0.0 0.0018 18.4 0.0 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain GIY-YIG PF01541.24 ACL94870.1 - 7.4e-11 42.2 0.3 9e-11 41.9 0.3 1.1 1 0 0 1 1 1 1 GIY-YIG catalytic domain T5orf172 PF10544.9 ACL94870.1 - 0.066 13.8 0.2 0.13 12.9 0.2 1.6 1 1 0 1 1 1 0 T5orf172 domain Metal_hydrol PF10118.9 ACL94871.1 - 1.9e-74 250.6 1.9 2.2e-74 250.4 1.9 1.0 1 0 0 1 1 1 1 Predicted metal-dependent hydrolase AurF PF11583.8 ACL94871.1 - 0.011 15.1 4.9 0.014 14.7 4.9 1.1 1 0 0 1 1 1 0 P-aminobenzoate N-oxygenase AurF TetR_N PF00440.23 ACL94872.1 - 2e-08 33.9 0.5 9.8e-08 31.7 0.1 2.3 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family NUDIX PF00293.28 ACL94873.1 - 6e-13 49.0 0.1 7.7e-13 48.6 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain GGDEF_2 PF17853.1 ACL94873.1 - 0.025 14.8 0.0 0.037 14.3 0.0 1.3 1 0 0 1 1 1 0 GGDEF-like domain NUDIX_2 PF13869.6 ACL94873.1 - 0.2 11.2 0.0 0.21 11.1 0.0 1.1 1 0 0 1 1 1 0 Nucleotide hydrolase ALAD PF00490.21 ACL94874.1 - 5.7e-133 443.0 0.2 6.5e-133 442.8 0.2 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase AP_endonuc_2 PF01261.24 ACL94874.1 - 0.015 14.8 0.0 0.039 13.4 0.0 1.7 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel K_oxygenase PF13434.6 ACL94875.1 - 4e-08 32.8 0.0 0.00015 21.1 0.0 2.9 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 ACL94875.1 - 5.8e-08 32.3 0.0 1.2e-05 24.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ACL94875.1 - 1.6e-07 30.1 0.0 5.8e-06 25.0 0.0 2.3 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ACL94875.1 - 5e-07 29.9 0.9 8.1e-06 26.0 0.1 3.0 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ACL94875.1 - 6.1e-07 28.9 0.3 3.1e-06 26.6 0.1 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 ACL94875.1 - 8.6e-06 25.2 0.0 0.00017 21.0 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ACL94875.1 - 1.6e-05 24.7 0.8 9.2e-05 22.2 0.0 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ACL94875.1 - 0.0016 17.6 0.0 0.04 13.0 0.0 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein Shikimate_DH PF01488.20 ACL94875.1 - 0.0025 17.9 0.0 0.19 11.8 0.0 3.3 4 0 0 4 4 4 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 ACL94875.1 - 0.02 15.4 0.3 0.034 14.6 0.0 1.7 2 0 0 2 2 1 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 ACL94875.1 - 0.058 12.5 0.0 0.058 12.5 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 ACL94875.1 - 0.49 10.4 2.2 7.6 6.5 0.1 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding Acyl-CoA_dh_1 PF00441.24 ACL94877.1 - 3.6e-50 170.1 1.3 5.6e-50 169.4 1.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ACL94877.1 - 7.3e-31 107.2 0.0 1.7e-30 106.0 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ACL94877.1 - 1.1e-26 92.9 0.1 2.3e-26 91.8 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ACL94877.1 - 7.6e-23 81.3 0.6 7.6e-23 81.3 0.6 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Amidohydro_2 PF04909.14 ACL94877.1 - 0.065 13.0 0.2 0.13 12.0 0.0 1.5 2 0 0 2 2 2 0 Amidohydrolase His_Phos_1 PF00300.22 ACL94878.1 - 1.1e-41 142.6 0.9 1.3e-41 142.4 0.9 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HAMP PF00672.25 ACL94878.1 - 0.021 15.2 0.2 0.08 13.3 0.1 2.1 2 0 0 2 2 2 0 HAMP domain ECH_2 PF16113.5 ACL94879.1 - 8e-120 400.3 0.0 9e-120 400.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 ACL94879.1 - 3.9e-30 105.0 0.0 8e-30 104.0 0.0 1.5 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase RXLR_WY PF18634.1 ACL94879.1 - 0.0046 16.9 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 RXLR phytopathogen effector protein WY-domain CopK PF11525.8 ACL94879.1 - 0.085 12.5 0.1 0.18 11.5 0.1 1.5 1 0 0 1 1 1 0 Copper resistance protein K LPAM_1 PF08139.12 ACL94880.1 - 0.0016 18.8 1.4 0.0047 17.3 1.4 1.8 1 0 0 1 1 1 1 Prokaryotic membrane lipoprotein lipid attachment site Ubie_methyltran PF01209.18 ACL94880.1 - 0.0073 15.7 0.0 0.058 12.7 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 ACL94880.1 - 0.032 14.0 0.0 0.081 12.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 ACL94880.1 - 0.071 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 ACL94880.1 - 0.12 13.1 0.0 0.22 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 ACL94880.1 - 0.17 12.5 0.0 0.29 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_2 PF03446.15 ACL94881.1 - 9.5e-47 159.1 3.7 1.4e-46 158.5 3.7 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ACL94881.1 - 3.9e-39 133.7 0.2 3.9e-39 133.7 0.2 1.9 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 ACL94881.1 - 6.9e-08 33.0 0.9 2.3e-07 31.3 0.9 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 ACL94881.1 - 1.5e-06 27.7 0.1 2.2e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 ACL94881.1 - 1.4e-05 24.8 0.2 2.7e-05 23.8 0.2 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 ACL94881.1 - 0.00014 21.8 2.9 0.00039 20.3 2.9 1.7 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 ACL94881.1 - 0.015 14.9 0.1 0.12 12.0 0.0 2.2 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GFO_IDH_MocA PF01408.22 ACL94881.1 - 0.069 14.0 0.9 0.31 11.9 0.4 2.1 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding PF02629.19 ACL94881.1 - 0.081 13.6 0.2 0.46 11.2 0.3 2.1 2 0 0 2 2 2 0 CoA binding domain Aminotran_1_2 PF00155.21 ACL94882.1 - 4.1e-76 256.5 0.0 4.7e-76 256.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 ACL94882.1 - 8e-05 21.3 0.0 0.00038 19.1 0.0 1.9 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 ACL94882.1 - 0.0049 15.9 0.0 0.0077 15.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 ACL94882.1 - 0.0062 15.9 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase ROS_MUCR PF05443.11 ACL94883.2 - 3.5e-48 162.8 0.0 4e-48 162.6 0.0 1.0 1 0 0 1 1 1 1 ROS/MUCR transcriptional regulator protein SHMT PF00464.19 ACL94884.1 - 2.5e-175 582.9 0.0 2.9e-175 582.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 ACL94884.1 - 3.8e-07 29.6 0.0 6e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ACL94884.1 - 1.7e-06 27.5 0.1 3.7e-06 26.4 0.1 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 ACL94884.1 - 3e-05 23.5 0.1 4.1e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family ATP-cone PF03477.16 ACL94885.1 - 6e-16 58.8 0.0 7.6e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 ATP cone domain TF_Zn_Ribbon PF08271.12 ACL94885.1 - 3.4e-05 23.3 0.9 0.16 11.5 0.1 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding zf-ribbon_3 PF13248.6 ACL94885.1 - 0.0033 16.8 0.8 2.3 7.7 0.1 2.3 2 0 0 2 2 2 2 zinc-ribbon domain Lar_restr_allev PF14354.6 ACL94885.1 - 0.013 15.8 2.4 0.054 13.9 2.5 1.9 1 1 0 1 1 1 0 Restriction alleviation protein Lar Ogr_Delta PF04606.12 ACL94885.1 - 0.025 14.5 0.3 6.4 6.8 0.0 2.4 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger TFIIS_C PF01096.18 ACL94885.1 - 0.029 14.2 1.3 0.29 11.0 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zinc_ribbon_9 PF14369.6 ACL94885.1 - 0.15 12.4 3.3 0.29 11.4 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon zf-C2H2_4 PF13894.6 ACL94885.1 - 0.21 12.5 1.9 2.5 9.2 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger DUF35_N PF12172.8 ACL94885.1 - 0.21 11.5 2.8 4.1 7.4 0.2 2.3 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Zn_Tnp_IS1595 PF12760.7 ACL94885.1 - 0.24 11.4 5.6 1.3 9.0 5.9 1.9 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-C4_ClpX PF06689.13 ACL94885.1 - 0.26 11.2 3.1 0.24 11.3 1.4 1.9 2 1 0 2 2 2 0 ClpX C4-type zinc finger UPF0547 PF10571.9 ACL94885.1 - 0.35 11.0 5.9 3.1 8.0 0.8 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Zn-ribbon_8 PF09723.10 ACL94885.1 - 0.64 10.2 4.7 2.2 8.4 4.7 2.0 1 1 0 1 1 1 0 Zinc ribbon domain Nudix_N_2 PF14803.6 ACL94885.1 - 1.3 9.0 4.3 5.7 6.9 4.4 2.1 1 1 0 1 1 1 0 Nudix N-terminal DNA_ligase_ZBD PF03119.16 ACL94885.1 - 5.5 7.1 6.4 21 5.2 0.2 2.9 2 1 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain DMRL_synthase PF00885.19 ACL94886.1 - 1.5e-36 125.4 0.1 1.6e-36 125.2 0.1 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase NusB PF01029.18 ACL94887.1 - 9e-34 116.6 0.0 1e-33 116.4 0.0 1.0 1 0 0 1 1 1 1 NusB family AIRS_C PF02769.22 ACL94888.3 - 1.5e-16 60.9 0.1 2.3e-16 60.3 0.1 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 ACL94888.3 - 5.9e-15 55.7 0.2 1.4e-14 54.5 0.2 1.6 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain FliL PF03748.14 ACL94889.2 - 0.081 13.5 0.0 0.14 12.8 0.0 1.4 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL CDRN PF05174.12 ACL94889.2 - 0.17 11.6 0.2 0.34 10.7 0.2 1.5 1 0 0 1 1 1 0 Cysteine-rich D. radiodurans N terminus H_PPase PF03030.16 ACL94890.1 - 1.2e-249 830.4 49.9 1.4e-249 830.2 49.9 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase Response_reg PF00072.24 ACL94891.1 - 1.3e-24 86.5 0.1 1.7e-24 86.1 0.1 1.2 1 0 0 1 1 1 1 Response regulator receiver domain BRCT_3 PF18428.1 ACL94891.1 - 0.17 12.0 0.0 0.75 9.9 0.0 1.8 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain SmpA_OmlA PF04355.13 ACL94892.1 - 1.4e-12 47.2 0.0 1.9e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 SmpA / OmlA family DUF3297 PF11730.8 ACL94892.1 - 0.053 13.4 0.0 0.084 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3297) Ubiq_cyt_C_chap PF03981.12 ACL94894.1 - 1.5e-34 119.1 0.1 1.7e-34 118.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Trans_reg_C PF00486.28 ACL94894.1 - 0.099 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal YceD PF02620.17 ACL94895.1 - 6.9e-12 45.6 0.0 1.6e-11 44.4 0.0 1.7 1 1 0 1 1 1 1 Large ribosomal RNA subunit accumulation protein YceD FA_synthesis PF02504.15 ACL94896.2 - 2.4e-109 365.3 2.1 2.7e-109 365.1 2.1 1.0 1 0 0 1 1 1 1 Fatty acid synthesis protein PTA_PTB PF01515.19 ACL94896.2 - 1.6e-05 24.4 0.1 3.1e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase ACP_syn_III_C PF08541.10 ACL94897.1 - 4.4e-34 116.5 0.4 1.4e-33 114.9 0.2 2.0 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 ACL94897.1 - 1.8e-31 107.8 2.1 3.7e-31 106.8 1.0 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 ACL94897.1 - 2.3e-08 33.7 0.3 2.3e-08 33.7 0.3 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain SBP_bac_5 PF00496.22 ACL94897.1 - 0.00021 20.4 0.0 0.0003 19.9 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Chal_sti_synt_N PF00195.19 ACL94897.1 - 0.0052 16.2 1.5 0.014 14.8 1.4 1.8 1 1 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain FAE1_CUT1_RppA PF08392.12 ACL94897.1 - 0.092 12.0 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 FAE1/Type III polyketide synthase-like protein Dodecin PF07311.12 ACL94897.1 - 0.36 11.1 2.6 2.5 8.4 0.1 2.4 2 0 0 2 2 2 0 Dodecin ketoacyl-synt PF00109.26 ACL94897.1 - 0.81 9.2 11.5 3.8 7.0 1.6 3.2 1 1 2 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain Bac_DNA_binding PF00216.21 ACL94898.1 - 9.2e-28 96.3 0.0 1e-27 96.2 0.0 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 ACL94898.1 - 3.5e-11 43.3 0.0 4e-11 43.1 0.0 1.0 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_euk_2 PF18289.1 ACL94898.1 - 5.1e-05 23.3 0.0 7.1e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 HU-CCDC81_euk_1 PF14908.6 ACL94898.1 - 0.014 15.5 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 1 HU-CCDC81_bac_2 PF18175.1 ACL94898.1 - 0.022 14.6 0.0 0.029 14.3 0.0 1.1 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 HU-DNA_bdg PF14848.6 ACL94898.1 - 0.17 11.9 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 DNA-binding domain MerR_1 PF13411.6 ACL94899.1 - 1e-22 80.0 0.0 1.4e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR PF00376.23 ACL94899.1 - 2.5e-09 36.7 0.0 5e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 MerR family regulatory protein HTH_Tnp_1 PF01527.20 ACL94899.1 - 0.0016 18.7 0.0 0.0035 17.6 0.0 1.5 1 0 0 1 1 1 1 Transposase HTH_17 PF12728.7 ACL94899.1 - 0.033 14.4 0.1 0.13 12.5 0.1 1.9 1 1 0 1 1 1 0 Helix-turn-helix domain DUF2842 PF11003.8 ACL94900.2 - 8.1e-17 61.2 7.7 9.4e-17 61.0 7.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2842) BTP PF05232.12 ACL94900.2 - 0.093 12.8 8.4 0.36 10.9 1.1 2.1 1 1 1 2 2 2 0 Chlorhexidine efflux transporter Transgly_assoc PF04226.13 ACL94902.1 - 1.4e-09 38.0 11.5 1.4e-09 38.0 11.5 2.1 2 0 0 2 2 2 1 Transglycosylase associated protein DUF1056 PF06341.11 ACL94902.1 - 0.04 14.2 0.1 0.04 14.2 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1056) DUF3159 PF11361.8 ACL94902.1 - 0.051 13.3 4.8 0.058 13.1 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3159) DUF3925 PF13063.6 ACL94902.1 - 0.14 12.4 0.6 0.14 12.4 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3925) COX15-CtaA PF02628.15 ACL94903.1 - 5.3e-112 374.1 22.8 6e-112 373.9 22.8 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF839 PF05787.13 ACL94904.2 - 7.9e-82 276.1 0.1 1.9e-80 271.5 0.1 2.9 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF839) Ribosomal_L13 PF00572.18 ACL94905.1 - 9.2e-53 177.8 0.0 1.1e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Trp_ring PF18669.1 ACL94905.1 - 0.1 12.8 1.1 1.9 8.7 0.1 2.3 2 0 0 2 2 2 0 Trimeric autotransporter adhesin Trp ring domain Ribosomal_S9 PF00380.19 ACL94906.1 - 1e-46 158.3 0.0 1.2e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Semialdhyde_dh PF01118.24 ACL94907.1 - 3.7e-08 33.8 0.1 9.7e-08 32.5 0.1 1.8 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DeoRC PF00455.22 ACL94907.1 - 0.095 12.6 0.5 2.3 8.1 0.1 2.8 3 1 0 3 3 3 0 DeoR C terminal sensor domain DUF1287 PF06940.11 ACL94908.1 - 2.7e-50 170.2 0.0 3.1e-50 170.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1287) PhaC_N PF07167.13 ACL94909.2 - 1.4e-76 256.0 0.0 2.2e-76 255.3 0.0 1.3 1 0 0 1 1 1 1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Abhydrolase_1 PF00561.20 ACL94909.2 - 3.6e-13 49.8 0.1 7.9e-12 45.4 0.1 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 ACL94909.2 - 0.031 13.8 0.4 0.19 11.2 0.5 2.2 2 1 0 2 2 2 0 Dienelactone hydrolase family DUF3141 PF11339.8 ACL94909.2 - 0.06 11.8 0.0 0.088 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) Dmrt1 PF12374.8 ACL94910.2 - 3.1 8.3 7.7 0.16 12.4 1.6 2.0 2 1 0 2 2 2 0 Double-sex mab3 related transcription factor 1 DUF3008 PF11450.8 ACL94910.2 - 9.5 6.5 12.5 0.14 12.3 3.9 2.3 2 0 0 2 2 2 0 Protein of unknwon function (DUF3008) Aminotran_1_2 PF00155.21 ACL94911.1 - 6e-57 193.5 0.0 6.8e-57 193.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Homoserine_dh PF00742.19 ACL94912.1 - 2.5e-58 196.8 0.0 3.6e-58 196.3 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 ACL94912.1 - 3.9e-13 50.1 0.0 7.3e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ACT PF01842.25 ACL94912.1 - 4.6e-12 45.5 0.0 1.2e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 ACL94912.1 - 0.006 16.5 0.0 0.02 14.9 0.0 1.9 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 ACL94912.1 - 0.026 15.1 0.0 0.061 13.9 0.0 1.7 1 0 0 1 1 1 0 ACT domain ACT_7 PF13840.6 ACL94912.1 - 0.046 13.5 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 ACT domain FBPase_glpX PF03320.13 ACL94913.1 - 2.5e-136 453.5 3.6 2.9e-136 453.4 3.6 1.0 1 0 0 1 1 1 1 Bacterial fructose-1,6-bisphosphatase, glpX-encoded FBPase PF00316.20 ACL94914.2 - 2.3e-56 190.3 0.0 3.1e-56 189.8 0.0 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain DHHA1 PF02272.19 ACL94915.1 - 2.7e-25 89.4 0.2 4.5e-25 88.7 0.2 1.4 1 0 0 1 1 1 1 DHHA1 domain RecJ_OB PF17768.1 ACL94915.1 - 2.9e-20 72.5 0.0 4.6e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 RecJ OB domain DHH PF01368.20 ACL94915.1 - 7.8e-07 29.3 0.0 1.5e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 DHH family CSD PF00313.22 ACL94916.1 - 7.6e-26 89.8 0.0 3.8e-14 52.3 0.0 2.2 2 0 0 2 2 2 2 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 ACL94916.1 - 6.1e-08 32.2 0.5 0.003 17.2 0.4 3.0 2 1 0 2 2 2 2 Ribonuclease B OB domain DUF192 PF02643.15 ACL94917.3 - 1.4e-31 108.5 0.0 1.9e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, COG1430 PDZ_6 PF17820.1 ACL94917.3 - 0.11 12.4 1.6 0.21 11.4 0.2 2.1 2 0 0 2 2 2 0 PDZ domain ETC_C1_NDUFA4 PF04800.12 ACL94918.1 - 6.7e-35 119.2 0.2 7.4e-35 119.1 0.2 1.0 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF2188 PF09954.9 ACL94918.1 - 0.013 15.6 0.2 0.038 14.1 0.2 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) Coat_F PF07875.12 ACL94924.1 - 0.065 13.5 0.0 0.088 13.1 0.0 1.2 1 0 0 1 1 1 0 Coat F domain TFA2_Winged_2 PF18121.1 ACL94924.1 - 0.14 11.8 0.0 0.77 9.5 0.0 2.0 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 Seryl_tRNA_N PF02403.22 ACL94924.1 - 0.17 12.1 0.0 0.19 12.0 0.0 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TetR_C_1 PF02909.17 ACL94926.2 - 0.055 13.3 0.1 8.6 6.2 0.0 2.8 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain FMN_dh PF01070.18 ACL94927.1 - 1.8e-109 366.0 0.0 2.1e-109 365.7 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.14 ACL94927.1 - 5.2e-08 32.5 0.1 0.0019 17.6 0.2 2.3 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 ACL94927.1 - 0.00092 18.3 0.1 0.0016 17.5 0.1 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 ACL94927.1 - 0.049 13.1 0.0 0.58 9.6 0.0 2.2 1 1 1 2 2 2 0 Histidine biosynthesis protein Amidohydro_2 PF04909.14 ACL94927.1 - 0.056 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Amidohydrolase Glu_synthase PF01645.17 ACL94927.1 - 0.091 11.9 0.2 0.14 11.2 0.2 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase DAHP_synth_1 PF00793.20 ACL94928.1 - 2.6e-103 344.6 0.0 3.2e-103 344.4 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family MCPsignal PF00015.21 ACL94930.1 - 2.1e-49 167.6 20.6 2.1e-49 167.6 20.6 3.4 1 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain ATG16 PF08614.11 ACL94930.1 - 0.0031 17.8 4.6 0.0031 17.8 4.6 3.0 2 1 0 2 2 1 1 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.9 ACL94930.1 - 0.034 14.4 6.6 1.9 8.8 0.1 4.5 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FRP PF18032.1 ACL94930.1 - 0.076 13.6 0.7 0.076 13.6 0.7 2.7 2 2 1 3 3 3 0 Photoprotection regulator fluorescence recovery protein NPV_P10 PF05531.12 ACL94930.1 - 0.1 13.1 5.3 0.79 10.2 1.0 3.6 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Noelin-1 PF12308.8 ACL94930.1 - 0.17 11.8 4.0 5.5 7.0 0.1 2.8 2 1 0 2 2 2 0 Neurogenesis glycoprotein Serine_rich PF08824.10 ACL94930.1 - 0.38 10.7 15.0 0.56 10.2 0.4 3.9 1 1 2 4 4 4 0 Serine rich protein interaction domain CorA PF01544.18 ACL94930.1 - 0.6 9.4 12.1 0.87 8.8 0.6 2.7 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein DUF948 PF06103.11 ACL94930.1 - 0.72 10.2 34.3 0.51 10.6 1.9 6.3 4 2 1 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF1759 PF03564.15 ACL94930.1 - 0.77 9.7 2.9 5 7.0 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1759) LXG PF04740.12 ACL94930.1 - 0.99 9.1 6.7 1.9 8.1 0.3 2.5 2 0 0 2 2 2 0 LXG domain of WXG superfamily Fib_alpha PF08702.10 ACL94930.1 - 1.9 8.7 4.5 13 5.9 0.5 2.8 2 2 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4047 PF13256.6 ACL94930.1 - 2.7 8.2 8.0 2 8.6 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4047) Nup88 PF10168.9 ACL94930.1 - 2.8 5.6 7.8 0.15 9.9 0.5 2.0 2 0 0 2 2 2 0 Nuclear pore component DUF1664 PF07889.12 ACL94930.1 - 2.9 7.9 10.8 3 7.9 2.0 3.2 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 ACL94930.1 - 3.4 6.8 4.9 17 4.5 0.6 2.5 2 0 0 2 2 2 0 TMPIT-like protein COX1 PF00115.20 ACL94932.1 - 1.8e-114 383.0 63.9 1.8e-114 383.0 63.9 1.6 2 0 0 2 2 2 1 Cytochrome C and Quinol oxidase polypeptide I DUF2871 PF11070.8 ACL94932.1 - 0.083 13.2 0.3 0.083 13.2 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2871) FixO PF02433.15 ACL94933.1 - 2.4e-98 327.9 0.0 2.9e-98 327.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C oxidase, mono-heme subunit/FixO Cytochrom_C PF00034.21 ACL94933.1 - 0.0018 19.4 0.1 0.1 13.7 0.1 2.5 1 1 0 1 1 1 1 Cytochrome c FixQ PF05545.11 ACL94934.1 - 3.3e-19 68.6 0.2 3.8e-19 68.4 0.2 1.0 1 0 0 1 1 1 1 Cbb3-type cytochrome oxidase component FixQ Cytochrome_CBB3 PF13442.6 ACL94935.1 - 1.4e-26 92.6 0.6 8.9e-13 48.4 0.0 2.6 3 0 0 3 3 3 2 Cytochrome C oxidase, cbb3-type, subunit III FixP_N PF14715.6 ACL94935.1 - 9.5e-25 86.1 8.9 1.5e-24 85.4 8.3 1.7 2 0 0 2 2 2 1 N-terminal domain of cytochrome oxidase-cbb3, FixP Cytochrom_C PF00034.21 ACL94935.1 - 1.4e-20 74.2 0.1 4.5e-10 40.5 0.0 3.2 2 1 0 2 2 2 2 Cytochrome c Cytochrom_C550 PF14495.6 ACL94935.1 - 0.00016 21.4 0.0 0.13 11.9 0.0 2.3 2 0 0 2 2 2 2 Cytochrome c-550 domain Paired_CXXCH_1 PF09699.10 ACL94935.1 - 0.00048 19.8 0.8 0.081 12.7 0.1 2.5 2 0 0 2 2 2 1 Doubled CXXCH motif (Paired_CXXCH_1) DUF3365 PF11845.8 ACL94935.1 - 0.03 14.7 0.0 2.2 8.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3365) GSu_C4xC__C2xCH PF09698.10 ACL94935.1 - 0.033 15.0 0.9 15 6.5 0.2 3.0 2 0 0 2 2 2 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) TPM_phosphatase PF04536.14 ACL94935.1 - 0.04 14.1 0.0 0.33 11.1 0.0 2.1 2 0 0 2 2 2 0 TPM domain Cytochrom_C_2 PF01322.20 ACL94935.1 - 0.051 14.5 0.6 8.6 7.3 0.0 2.3 2 0 0 2 2 2 0 Cytochrome C' Cytochrome_C7 PF14522.6 ACL94935.1 - 0.056 13.4 0.1 14 5.8 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c Haem_bd PF14376.6 ACL94935.1 - 0.081 12.9 0.4 23 4.9 0.0 3.1 1 1 1 2 2 2 0 Haem-binding domain Cytochrom_C1 PF02167.15 ACL94935.1 - 0.16 11.7 0.1 8.2 6.1 0.0 2.1 1 1 1 2 2 2 0 Cytochrome C1 family MCR PF18509.1 ACL94935.1 - 5.7 6.6 6.8 1.3 8.7 0.6 2.4 2 0 0 2 2 2 0 Magnetochrome domain Fer4_18 PF13746.6 ACL94936.1 - 4.6e-39 133.1 6.7 1.3e-38 131.7 6.7 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain FixG_C PF11614.8 ACL94936.1 - 1.3e-26 93.1 0.0 2.1e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 IG-like fold at C-terminal of FixG, putative oxidoreductase Fer4_5 PF12801.7 ACL94936.1 - 4.4e-10 39.4 3.1 4.4e-10 39.4 3.1 3.5 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_8 PF13183.6 ACL94936.1 - 6.7e-08 32.9 10.1 2.1e-05 24.8 2.0 2.6 3 0 0 3 3 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 ACL94936.1 - 6.2e-07 29.9 11.4 0.0016 19.0 2.4 3.1 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 ACL94936.1 - 1.1e-06 29.0 11.0 6e-05 23.5 1.4 3.0 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 ACL94936.1 - 2e-06 27.9 12.8 0.00091 19.4 2.6 3.3 2 1 2 4 4 4 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 ACL94936.1 - 0.0014 18.7 17.1 0.0021 18.1 12.0 3.1 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 ACL94936.1 - 0.0018 18.4 13.3 0.056 13.6 1.3 2.9 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 ACL94936.1 - 0.002 18.5 21.8 0.0064 16.9 2.6 3.7 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_6 PF12837.7 ACL94936.1 - 0.0029 17.6 19.5 0.0084 16.1 5.1 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4 PF00037.27 ACL94936.1 - 0.0036 17.1 16.3 0.0097 15.7 3.6 3.4 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_3 PF12798.7 ACL94936.1 - 0.14 13.2 26.2 0.31 12.1 5.2 4.0 4 0 0 4 4 4 0 4Fe-4S binding domain Fer4_13 PF13370.6 ACL94936.1 - 0.19 12.3 14.2 1.9 9.1 2.7 2.9 1 1 1 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_16 PF13484.6 ACL94936.1 - 0.65 11.0 19.1 0.41 11.6 5.1 3.2 3 1 0 3 3 2 0 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 ACL94936.1 - 4.9 7.5 27.8 0.14 12.3 2.6 3.6 4 0 0 4 4 4 0 4Fe-4S binding domain FixH PF05751.11 ACL94937.1 - 4.3e-39 133.9 0.1 5e-39 133.7 0.1 1.0 1 0 0 1 1 1 1 FixH YtkA PF13115.6 ACL94937.1 - 0.13 12.8 0.0 0.2 12.3 0.0 1.4 1 0 0 1 1 1 0 YtkA-like E1-E2_ATPase PF00122.20 ACL94938.1 - 1.3e-42 145.4 3.2 1.5e-42 145.2 0.5 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 ACL94938.1 - 7.4e-29 101.5 3.2 1.6e-28 100.5 3.2 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 ACL94938.1 - 6.6e-11 42.5 0.0 1.4e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 ACL94938.1 - 0.00097 19.0 1.6 0.0016 18.3 1.6 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase FixS PF03597.15 ACL94939.1 - 9.8e-19 66.8 0.1 1.2e-18 66.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase maturation protein cbb3-type PEP-CTERM PF07589.11 ACL94939.1 - 0.16 12.1 1.7 0.23 11.6 1.7 1.2 1 0 0 1 1 1 0 PEP-CTERM motif OmpW PF03922.14 ACL94940.1 - 2.2e-69 233.2 1.0 2.5e-69 233.0 1.0 1.0 1 0 0 1 1 1 1 OmpW family OMP_b-brl PF13505.6 ACL94940.1 - 2.5e-09 37.5 5.1 3.9e-09 36.9 5.1 1.3 1 1 0 1 1 1 1 Outer membrane protein beta-barrel domain HTH_Crp_2 PF13545.6 ACL94941.1 - 3.6e-12 46.1 0.0 5.8e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain cNMP_binding PF00027.29 ACL94941.1 - 2.1e-11 43.8 0.0 3.2e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Radical_SAM PF04055.21 ACL94942.1 - 4.1e-24 85.8 0.0 6.7e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily HemN_C PF06969.16 ACL94942.1 - 3.9e-06 26.8 0.0 1.3e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 HemN C-terminal domain cNMP_binding PF00027.29 ACL94943.1 - 5.2e-18 64.9 0.0 1.3e-17 63.6 0.0 1.7 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain HTH_Crp_2 PF13545.6 ACL94943.1 - 2.9e-09 36.8 0.3 6.5e-09 35.6 0.3 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain DUF1863 PF08937.11 ACL94944.1 - 3.9e-44 150.1 0.0 7.1e-44 149.3 0.0 1.5 1 0 0 1 1 1 1 MTH538 TIR-like domain (DUF1863) TIR_2 PF13676.6 ACL94944.1 - 1.5e-13 51.4 0.5 1.3e-11 45.2 0.1 3.6 3 1 0 3 3 3 1 TIR domain TPR_1 PF00515.28 ACL94944.1 - 0.00081 19.1 1.5 0.67 9.9 0.1 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 ACL94944.1 - 0.00094 19.2 3.5 0.46 10.8 0.1 4.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 ACL94944.1 - 0.0087 15.9 26.3 0.055 13.3 0.1 6.6 7 0 0 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ACL94944.1 - 0.018 15.3 0.9 5 7.4 0.3 4.2 3 2 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TIR PF01582.20 ACL94944.1 - 0.037 13.8 0.0 0.084 12.7 0.0 1.5 1 0 0 1 1 1 0 TIR domain TPR_12 PF13424.6 ACL94944.1 - 0.072 13.4 0.2 0.072 13.4 0.2 7.0 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_2 PF07719.17 ACL94944.1 - 0.081 13.1 19.1 0.38 11.0 0.5 6.7 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_7 PF13176.6 ACL94944.1 - 0.14 12.3 8.6 3.7 7.8 0.1 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 ACL94944.1 - 0.23 12.2 44.0 0.2 12.4 0.8 8.5 8 1 0 8 8 8 0 Tetratricopeptide repeat Guanylate_cyc PF00211.20 ACL94946.1 - 2.4e-08 33.8 0.0 4e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF4071 PF13281.6 ACL94946.1 - 0.048 12.7 0.0 0.07 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) TPR_MalT PF17874.1 ACL94946.1 - 0.7 9.2 9.1 0.068 12.5 3.1 2.0 2 0 0 2 2 2 0 MalT-like TPR region Sec20 PF03908.13 ACL94949.1 - 0.035 14.0 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 Sec20 Aldose_epim PF01263.20 ACL94950.1 - 6.8e-98 327.7 0.0 7.8e-98 327.5 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase FCD PF07729.12 ACL94952.1 - 1.1e-18 67.8 7.4 1.1e-18 67.8 7.4 1.6 2 0 0 2 2 2 1 FCD domain GntR PF00392.21 ACL94952.1 - 5.1e-11 42.1 0.3 5.1e-11 42.1 0.3 2.5 3 0 0 3 3 3 1 Bacterial regulatory proteins, gntR family MarR_2 PF12802.7 ACL94952.1 - 0.0026 17.6 0.1 0.0081 16.0 0.1 1.9 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 ACL94952.1 - 0.043 13.7 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB ILVD_EDD PF00920.21 ACL94953.1 - 7.4e-151 503.3 0.0 8.4e-151 503.1 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family Alpha-L-AF_C PF06964.12 ACL94954.2 - 2.1e-38 132.1 0.1 5.1e-38 130.8 0.0 1.7 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminal domain DAO PF01266.24 ACL94955.1 - 8.1e-06 25.6 0.2 0.078 12.6 0.0 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ACL94955.1 - 2e-05 24.0 0.4 3.6e-05 23.2 0.4 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ACL94955.1 - 0.00025 20.4 0.0 0.0013 18.0 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ACL94955.1 - 0.00028 20.3 0.1 0.00053 19.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 ACL94955.1 - 0.0026 16.9 0.1 0.033 13.3 0.0 2.3 2 1 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 ACL94955.1 - 0.0031 16.3 0.0 0.028 13.1 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 ACL94955.1 - 0.065 12.5 0.1 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 ACL94955.1 - 0.1 11.7 0.3 1.1 8.2 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.27 ACL94955.1 - 0.11 13.0 0.1 0.62 10.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cys_Met_Meta_PP PF01053.20 ACL94956.1 - 4e-86 288.9 0.0 5e-86 288.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 ACL94956.1 - 0.0098 15.2 0.1 0.015 14.7 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 ACL94956.1 - 0.024 13.6 0.0 0.033 13.2 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-V Rhodanese PF00581.20 ACL94957.1 - 2.8e-29 101.8 0.0 2.2e-16 60.3 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain NAD_binding_8 PF13450.6 ACL94957.1 - 0.11 12.7 0.4 1.2 9.4 0.1 2.5 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain PALP PF00291.25 ACL94958.1 - 7.6e-68 229.1 1.4 8.6e-68 228.9 1.4 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF2620 PF10941.8 ACL94958.1 - 0.12 12.5 0.6 2.6 8.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF2620 CMAS PF02353.20 ACL94959.1 - 6.8e-86 287.9 0.0 8.4e-86 287.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 ACL94959.1 - 1.7e-14 54.3 0.0 3.3e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ACL94959.1 - 7.4e-12 45.8 0.0 1.4e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ACL94959.1 - 6.8e-11 42.8 0.0 1.1e-10 42.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ACL94959.1 - 9.6e-11 41.8 0.0 1.5e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ACL94959.1 - 7.4e-06 25.8 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 ACL94959.1 - 0.0021 18.2 0.0 0.0043 17.2 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 ACL94959.1 - 0.0043 16.6 0.0 0.0068 16.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 ACL94959.1 - 0.0076 16.0 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FAD_binding_7 PF03441.14 ACL94960.1 - 1.2e-84 282.9 0.9 1.2e-84 282.9 0.9 1.5 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 ACL94960.1 - 1.2e-51 174.9 0.0 2e-51 174.2 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase DAHP_synth_1 PF00793.20 ACL94961.1 - 2e-71 240.1 0.0 2.5e-71 239.8 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Epimerase PF01370.21 ACL94962.1 - 5.9e-38 130.7 0.0 7e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ACL94962.1 - 1.4e-16 60.8 0.0 2e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ACL94962.1 - 2.4e-09 36.6 0.0 5.1e-09 35.5 0.0 1.6 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ACL94962.1 - 3.6e-08 32.8 0.0 2.7e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 ACL94962.1 - 5.7e-06 25.7 0.0 0.045 12.9 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 ACL94962.1 - 3.8e-05 23.0 0.0 0.087 11.9 0.0 2.6 2 2 0 2 2 2 2 Polysaccharide biosynthesis protein adh_short PF00106.25 ACL94962.1 - 0.0053 16.2 0.1 0.0089 15.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ACL94962.1 - 0.014 15.3 0.0 0.092 12.6 0.0 2.3 1 1 1 2 2 2 0 KR domain Sacchrp_dh_NADP PF03435.18 ACL94962.1 - 0.15 12.3 0.0 6.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Ldh_1_N PF00056.23 ACL94962.1 - 0.16 12.1 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain OB_aCoA_assoc PF01796.17 ACL94963.1 - 2.9e-11 43.2 0.1 6.1e-11 42.2 0.1 1.6 1 0 0 1 1 1 1 DUF35 OB-fold domain, acyl-CoA-associated ACP_syn_III_C PF08541.10 ACL94963.1 - 2.4e-08 34.0 0.1 2.4e-08 34.0 0.1 2.2 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Thiolase_C PF02803.18 ACL94963.1 - 0.00084 19.0 0.1 0.002 17.8 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain DUF35_N PF12172.8 ACL94963.1 - 0.001 18.9 0.0 0.0023 17.7 0.0 1.7 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) ACP_syn_III PF08545.10 ACL94963.1 - 0.11 12.4 3.3 0.43 10.5 0.7 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Chal_sti_synt_N PF00195.19 ACL94963.1 - 0.13 11.7 0.8 1.7 8.0 0.0 2.4 2 0 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain Thiolase_N PF00108.23 ACL94964.1 - 1.3e-17 64.0 0.0 2.6e-17 63.1 0.0 1.5 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ACL94964.1 - 2.9e-08 33.4 0.0 1.4e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ACL94964.1 - 6.8e-05 22.6 0.6 0.029 14.0 0.1 2.8 3 0 0 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain DUF3089 PF11288.8 ACL94965.1 - 4e-63 212.5 0.0 5.3e-63 212.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) VirB8 PF04335.13 ACL94965.1 - 0.021 14.7 2.9 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 VirB8 protein APH PF01636.23 ACL94967.1 - 3.8e-41 141.6 8.3 4.9e-41 141.2 8.3 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 ACL94967.1 - 0.00036 19.5 0.0 0.00055 18.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) APH_6_hur PF04655.14 ACL94967.1 - 0.0079 15.6 0.2 0.011 15.2 0.2 1.2 1 0 0 1 1 1 1 Aminoglycoside/hydroxyurea antibiotic resistance kinase EcKinase PF02958.20 ACL94967.1 - 0.0094 15.3 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 ACL94967.1 - 0.25 10.9 0.0 0.37 10.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF808 PF05661.12 ACL94968.1 - 2.8e-117 391.1 10.9 3.2e-117 390.9 10.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF808) LysE PF01810.18 ACL94968.1 - 0.22 11.0 0.1 0.22 11.0 0.1 3.2 2 1 1 3 3 3 0 LysE type translocator Helicase_C PF00271.31 ACL94969.1 - 2.7e-15 56.7 0.0 4.8e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ACL94969.1 - 1.1e-14 54.6 0.0 2.6e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 ACL94969.1 - 4.4e-07 30.1 0.0 1.1e-06 28.8 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 ACL94969.1 - 0.0056 16.4 1.8 0.014 15.1 1.8 1.7 1 1 0 1 1 1 1 AAA domain SecA_DEAD PF07517.14 ACL94969.1 - 0.079 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 SecA DEAD-like domain DUF2791 PF10923.8 ACL94969.1 - 0.11 11.3 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) TsaE PF02367.17 ACL94969.1 - 0.24 11.4 0.2 0.93 9.5 0.0 2.0 1 1 1 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 ACL94969.1 - 0.25 11.7 4.5 0.16 12.3 0.2 2.6 3 0 0 3 3 3 0 AAA ATPase domain ABC_tran PF00005.27 ACL94971.1 - 1.2e-30 106.8 0.0 1.6e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ACL94971.1 - 2.7e-13 50.4 0.1 4.6e-06 26.7 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ACL94971.1 - 1.6e-07 31.0 0.0 0.00071 19.1 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 ACL94971.1 - 1.9e-05 25.2 0.3 0.19 12.3 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ACL94971.1 - 9.1e-05 22.9 2.3 0.0012 19.2 2.3 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 ACL94971.1 - 0.00023 20.8 0.5 0.00048 19.8 0.1 1.7 2 0 0 2 2 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.9 ACL94971.1 - 0.00056 18.8 0.6 0.86 8.3 0.1 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 ACL94971.1 - 0.0011 19.3 0.6 0.0081 16.4 0.6 2.3 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ACL94971.1 - 0.0014 18.5 0.1 0.003 17.5 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 ACL94971.1 - 0.0014 18.3 0.0 0.0022 17.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_13 PF13166.6 ACL94971.1 - 0.0015 17.3 0.0 0.035 12.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ACL94971.1 - 0.0017 18.5 0.9 0.025 14.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 ACL94971.1 - 0.002 18.7 0.0 0.0034 17.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 ACL94971.1 - 0.0033 17.2 0.1 0.092 12.5 0.1 2.3 2 0 0 2 2 2 1 Cytidylate kinase AAA_28 PF13521.6 ACL94971.1 - 0.0041 17.4 1.9 0.082 13.2 0.1 3.0 2 1 1 3 3 3 1 AAA domain AAA PF00004.29 ACL94971.1 - 0.0047 17.4 0.1 5.1 7.5 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 ACL94971.1 - 0.019 15.1 0.4 0.053 13.6 0.2 1.9 2 1 1 3 3 2 0 50S ribosome-binding GTPase AAA_25 PF13481.6 ACL94971.1 - 0.022 14.3 1.8 0.091 12.3 0.1 2.2 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 ACL94971.1 - 0.034 14.1 1.0 0.057 13.3 0.1 1.8 2 0 0 2 2 2 0 NACHT domain Mg_chelatase PF01078.21 ACL94971.1 - 0.04 13.3 0.7 0.15 11.4 0.1 2.0 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 ACL94971.1 - 0.043 13.5 0.3 0.19 11.5 0.0 2.0 1 1 1 2 2 2 0 AAA domain ATPase_2 PF01637.18 ACL94971.1 - 0.077 12.9 0.0 0.55 10.1 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea FtsK_SpoIIIE PF01580.18 ACL94971.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family dNK PF01712.19 ACL94971.1 - 0.15 11.9 0.2 21 4.9 0.0 2.5 3 0 0 3 3 3 0 Deoxynucleoside kinase PduV-EutP PF10662.9 ACL94971.1 - 0.19 11.5 0.0 4.5 7.0 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.17 ACL94971.1 - 0.2 11.4 1.7 1.9 8.2 0.1 2.7 2 1 1 3 3 3 0 IstB-like ATP binding protein AAA_14 PF13173.6 ACL94971.1 - 0.26 11.3 0.1 2 8.5 0.0 2.3 2 1 1 3 3 3 0 AAA domain Adeno_IVa2 PF02456.15 ACL94971.1 - 0.29 9.9 0.0 0.43 9.3 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein NB-ARC PF00931.22 ACL94971.1 - 0.3 10.3 0.1 1.2 8.3 0.1 1.8 2 0 0 2 2 2 0 NB-ARC domain BPD_transp_1 PF00528.22 ACL94972.1 - 3.3e-23 82.4 9.5 3.3e-23 82.4 9.5 1.8 2 0 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component DUF4064 PF13273.6 ACL94972.1 - 0.81 10.0 7.7 8.8 6.7 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) SBP_bac_3 PF00497.20 ACL94973.2 - 3.9e-66 222.7 0.0 4.4e-66 222.5 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 ACL94973.2 - 3.9e-09 36.7 0.0 6.3e-08 32.8 0.0 2.4 1 1 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site ACP_syn_III PF08545.10 ACL94974.2 - 1e-20 73.3 0.4 2e-20 72.4 0.4 1.5 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 ACL94974.2 - 3.4e-19 68.8 0.0 6.4e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Chal_sti_synt_N PF00195.19 ACL94974.2 - 9.2e-08 31.8 0.1 2.1e-07 30.6 0.1 1.7 1 1 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Thiolase_N PF00108.23 ACL94974.2 - 5.7e-05 22.6 0.3 8.7e-05 22.0 0.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.26 ACL94974.2 - 0.0094 15.5 1.6 0.022 14.3 0.6 2.0 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain FA_hydroxylase PF04116.13 ACL94976.1 - 8.4e-28 97.4 15.0 8.4e-28 97.4 15.0 2.0 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily Y1_Tnp PF01797.16 ACL94977.1 - 8.4e-14 51.7 0.0 1.1e-13 51.4 0.0 1.1 1 0 0 1 1 1 1 Transposase IS200 like DctP PF03480.13 ACL94978.1 - 6.1e-88 294.9 0.0 7.4e-88 294.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein, family 7 DctQ PF04290.12 ACL94979.1 - 6.7e-23 81.1 11.1 6.7e-23 81.1 11.1 1.5 1 1 1 2 2 2 1 Tripartite ATP-independent periplasmic transporters, DctQ component DctM PF06808.12 ACL94980.1 - 1.1e-111 373.6 60.2 1.3e-111 373.4 60.2 1.0 1 0 0 1 1 1 1 Tripartite ATP-independent periplasmic transporter, DctM component Nitroreductase PF00881.24 ACL94981.1 - 2.1e-20 73.5 0.0 2.6e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 ACL94981.1 - 7e-05 22.5 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 Putative TM nitroreductase HTH_32 PF13565.6 ACL94982.1 - 4.4 8.0 9.7 3.3 8.4 0.7 3.1 2 1 1 3 3 3 0 Homeodomain-like domain Usp PF00582.26 ACL94984.2 - 3.2e-13 50.4 1.3 1.2e-05 25.8 0.4 3.2 2 1 0 2 2 2 2 Universal stress protein family GGDEF_2 PF17853.1 ACL94984.2 - 0.0097 16.2 0.7 0.019 15.2 0.5 1.6 1 1 0 1 1 1 1 GGDEF-like domain DUF4785 PF16024.5 ACL94985.1 - 0.0049 15.7 0.0 0.0055 15.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4785) Lipid_bd PF12888.7 ACL94986.1 - 0.015 15.8 0.4 0.024 15.0 0.4 1.2 1 0 0 1 1 1 0 Lipid-binding putative hydrolase PPC PF04151.15 ACL94986.1 - 0.14 13.3 0.5 0.59 11.3 0.2 2.2 2 0 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain AAA PF00004.29 ACL94987.1 - 7.2e-13 49.1 0.0 1.2e-12 48.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ACL94987.1 - 1.9e-11 44.1 0.1 4.2e-11 43.0 0.1 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 ACL94987.1 - 1.8e-07 31.0 0.0 0.021 14.5 0.0 2.2 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 ACL94987.1 - 2.6e-05 24.5 0.0 6.7e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 ACL94987.1 - 0.00013 22.1 0.0 0.00019 21.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 ACL94987.1 - 0.00053 20.4 1.4 0.0069 16.8 0.7 2.5 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 ACL94987.1 - 0.0021 17.8 0.2 0.006 16.3 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 ACL94987.1 - 0.0021 17.3 0.9 0.025 13.8 0.0 2.3 1 1 0 2 2 2 1 TIP49 P-loop domain AAA_19 PF13245.6 ACL94987.1 - 0.0028 18.0 0.6 0.027 14.8 0.6 2.2 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 ACL94987.1 - 0.0038 16.5 0.0 0.0049 16.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 ACL94987.1 - 0.0043 16.8 0.0 0.0072 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 ACL94987.1 - 0.006 16.0 0.1 0.013 14.9 0.0 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 ACL94987.1 - 0.0068 15.9 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region NACHT PF05729.12 ACL94987.1 - 0.012 15.5 0.1 0.056 13.4 0.0 2.0 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 ACL94987.1 - 0.016 15.2 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 ACL94987.1 - 0.02 14.1 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 ACL94987.1 - 0.022 15.3 0.0 0.053 14.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.11 ACL94987.1 - 0.028 14.3 0.0 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 ACL94987.1 - 0.028 14.8 0.1 0.057 13.8 0.1 1.8 1 1 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.6 ACL94987.1 - 0.038 14.1 0.0 0.1 12.7 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.6 ACL94987.1 - 0.039 13.7 0.0 0.054 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 ACL94987.1 - 0.048 13.7 0.1 0.12 12.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 ACL94987.1 - 0.075 12.4 0.0 0.17 11.2 0.0 1.5 2 0 0 2 2 2 0 KaiC T2SSE PF00437.20 ACL94987.1 - 0.19 10.8 0.0 0.33 10.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Acetyltransf_3 PF13302.7 ACL94988.2 - 1.9e-15 57.8 0.1 2.4e-15 57.4 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ACL94988.2 - 5.4e-10 39.5 0.1 7.2e-10 39.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 ACL94988.2 - 6.3e-10 38.9 0.5 1.6e-09 37.6 0.5 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ACL94988.2 - 2.2e-09 37.6 0.0 2.9e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ACL94988.2 - 0.035 14.5 0.0 0.057 13.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3291 PF11695.8 ACL94988.2 - 0.14 11.8 0.5 0.39 10.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3291) TPR_2 PF07719.17 ACL94989.1 - 3.6e-14 51.6 24.0 0.00031 20.6 0.1 7.4 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 ACL94989.1 - 8.6e-14 50.9 3.7 0.016 15.6 0.0 6.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 ACL94989.1 - 3.4e-13 48.8 7.5 0.022 14.6 0.5 6.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 ACL94989.1 - 4.8e-11 43.1 25.1 0.00041 20.9 0.0 5.0 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 ACL94989.1 - 6e-11 41.7 7.5 0.0094 16.1 0.0 6.9 8 1 1 9 9 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 ACL94989.1 - 1.8e-08 34.5 16.8 0.0023 18.2 0.1 5.8 2 2 4 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 ACL94989.1 - 1.1e-06 29.1 22.1 0.0012 19.3 0.2 4.6 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 ACL94989.1 - 1.5e-06 27.8 7.3 0.28 11.3 0.1 6.0 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 ACL94989.1 - 1.2e-05 25.7 27.4 0.0075 17.0 0.7 7.6 1 1 7 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 ACL94989.1 - 3.1e-05 23.6 2.1 0.3 10.8 0.0 4.5 3 1 1 4 4 4 1 TPR repeat TPR_9 PF13371.6 ACL94989.1 - 0.00028 21.0 14.8 0.062 13.5 0.8 4.5 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 ACL94989.1 - 0.0047 16.7 10.8 0.41 10.6 1.1 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Glyco_transf_9 PF01075.17 ACL94989.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) HEAT_PBS PF03130.16 ACL94989.1 - 4.7 8.2 8.1 23 6.1 0.5 4.1 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat FlbT PF07378.11 ACL94990.1 - 3.2e-46 156.5 0.1 3.6e-46 156.3 0.1 1.0 1 0 0 1 1 1 1 Flagellar protein FlbT Abi_HHR PF07815.14 ACL94990.1 - 0.062 13.5 0.0 0.23 11.6 0.0 1.8 2 0 0 2 2 2 0 Abl-interactor HHR FlaF PF07309.11 ACL94991.1 - 2.1e-37 127.6 0.3 2.4e-37 127.4 0.3 1.0 1 0 0 1 1 1 1 Flagellar protein FlaF FliD_N PF02465.18 ACL94991.1 - 0.08 13.6 0.0 0.11 13.2 0.0 1.3 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Flagellin_N PF00669.20 ACL94992.1 - 2.2e-20 73.2 17.0 2.2e-20 73.2 17.0 3.0 3 0 0 3 3 3 2 Bacterial flagellin N-terminal helical region Flagellin_C PF00700.21 ACL94992.1 - 7.1e-13 48.7 3.8 7.1e-13 48.7 3.8 3.8 2 2 2 4 4 4 1 Bacterial flagellin C-terminal helical region DUF2203 PF09969.9 ACL94992.1 - 0.059 14.1 0.3 2.1 9.1 0.1 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) HALZ PF02183.18 ACL94992.1 - 0.18 12.0 0.1 0.18 12.0 0.1 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF4854 PF16146.5 ACL94992.1 - 5.1 7.5 6.9 1.1 9.6 1.7 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4854) Flagellin_N PF00669.20 ACL94993.1 - 7.9e-22 77.9 18.3 7.9e-22 77.9 18.3 2.9 3 0 0 3 3 3 2 Bacterial flagellin N-terminal helical region Flagellin_C PF00700.21 ACL94993.1 - 3.2e-13 49.8 3.3 3.2e-13 49.8 3.3 3.4 2 1 2 4 4 4 1 Bacterial flagellin C-terminal helical region MapZ_EC1 PF18041.1 ACL94993.1 - 0.05 13.8 0.2 0.05 13.8 0.2 2.7 3 0 0 3 3 3 0 MapZ extracellular domain 1 HALZ PF02183.18 ACL94993.1 - 0.086 13.1 0.1 0.086 13.1 0.1 1.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper FlaG PF03646.15 ACL94994.1 - 2.6e-05 24.3 0.0 3.6e-05 23.8 0.0 1.3 1 1 0 1 1 1 1 FlaG protein IgG_binding_B PF01378.17 ACL94994.1 - 0.011 15.8 0.0 0.87 9.7 0.1 2.2 2 0 0 2 2 2 0 B domain Flagellin_N PF00669.20 ACL94995.1 - 1.3e-32 112.8 14.6 1.3e-32 112.8 14.6 3.1 2 1 1 3 3 3 2 Bacterial flagellin N-terminal helical region Flagellin_C PF00700.21 ACL94995.1 - 2.6e-12 46.9 2.7 2.6e-12 46.9 2.7 2.6 2 1 1 3 3 3 1 Bacterial flagellin C-terminal helical region RPW8 PF05659.11 ACL94995.1 - 0.1 12.3 0.1 0.53 10.0 0.0 2.2 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Acetyltransf_3 PF13302.7 ACL94996.1 - 1.1e-15 58.6 0.2 1.4e-15 58.2 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 ACL94996.1 - 3.5e-12 46.2 1.4 1.4e-11 44.2 1.4 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ACL94996.1 - 3e-06 27.4 0.0 4.1e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 ACL94996.1 - 4.4e-05 23.7 0.0 5.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Flagellin_IN PF07196.13 ACL94997.1 - 0.06 13.6 4.0 0.15 12.3 0.2 3.8 3 0 0 3 3 3 0 Flagellin hook IN motif LPAM_1 PF08139.12 ACL94999.1 - 0.75 10.4 5.3 11 6.7 5.3 2.4 1 1 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site SSB PF00436.25 ACL95000.1 - 1.5e-38 131.0 0.5 2e-38 130.6 0.5 1.1 1 0 0 1 1 1 1 Single-strand binding protein family tRNA_anti-codon PF01336.25 ACL95000.1 - 0.039 13.9 0.1 0.07 13.1 0.1 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Acetyltransf_1 PF00583.25 ACL95002.1 - 1e-13 51.5 0.1 1.3e-13 51.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ACL95002.1 - 6.4e-07 29.7 0.0 1e-06 29.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ACL95002.1 - 7.2e-07 29.2 0.0 9.7e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ACL95002.1 - 0.00017 21.5 0.0 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 ACL95002.1 - 0.14 12.3 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PEP-utilizers_C PF02896.18 ACL95003.1 - 7.8e-91 304.2 0.0 1.1e-90 303.7 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.19 ACL95003.1 - 1e-68 232.0 0.0 2.2e-65 221.1 0.0 3.1 1 1 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 ACL95003.1 - 8.2e-29 99.2 1.1 1.9e-28 98.0 1.1 1.6 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain Pirin PF02678.16 ACL95004.1 - 1.9e-35 121.1 0.1 2.7e-35 120.6 0.1 1.2 1 0 0 1 1 1 1 Pirin Pirin_C_2 PF17954.1 ACL95004.1 - 1.1e-18 67.2 0.0 1.9e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Quercetinase C-terminal cupin domain Cupin_2 PF07883.11 ACL95004.1 - 4.2e-05 23.2 0.6 7.1e-05 22.5 0.1 1.6 2 0 0 2 2 2 1 Cupin domain LysR_substrate PF03466.20 ACL95006.1 - 1.4e-42 145.4 10.6 2.1e-42 144.9 10.6 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 ACL95006.1 - 1e-15 57.4 5.9 1e-15 57.4 5.9 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family CAAP1 PF15335.6 ACL95007.1 - 1.2e-13 51.4 0.0 1.1 9.8 0.0 10.3 7 3 2 12 12 12 2 Caspase activity and apoptosis inhibitor 1 Sigma70_r4_2 PF08281.12 ACL95007.1 - 3.5e-07 29.8 0.0 0.6 9.8 0.1 6.0 6 0 0 6 6 6 2 Sigma-70, region 4 DUF4351 PF14261.6 ACL95007.1 - 8.6e-05 22.5 48.7 6.7 6.9 0.2 17.6 4 4 10 16 16 16 1 Domain of unknown function (DUF4351) HTH_26 PF13443.6 ACL95007.1 - 0.00018 21.9 37.2 49 4.5 0.4 14.0 3 3 10 15 15 15 0 Cro/C1-type HTH DNA-binding domain LRR_8 PF13855.6 ACL95007.1 - 0.011 15.5 4.6 4.3 7.2 0.1 5.8 6 0 0 6 6 6 0 Leucine rich repeat DUF1507 PF07408.11 ACL95007.1 - 0.19 11.6 0.7 42 4.1 0.1 4.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1507) DUF1779 PF08680.10 ACL95007.1 - 0.41 10.8 3.3 15 5.7 0.2 4.3 3 1 0 4 4 4 0 TATA-box binding SAM_3 PF18016.1 ACL95007.1 - 2.5 8.0 19.6 75 3.3 0.1 9.9 6 3 5 13 13 13 0 SAM domain (Sterile alpha motif) HSP70 PF00012.20 ACL95008.1 - 2.3e-19 69.1 0.0 7.1e-10 37.7 0.0 2.7 2 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 ACL95008.1 - 0.00013 21.0 0.0 0.16 10.8 0.0 3.0 3 0 0 3 3 3 2 MreB/Mbl protein SrfB PF07520.11 ACL95008.1 - 0.021 12.7 0.0 0.073 10.9 0.0 1.7 2 0 0 2 2 2 0 Virulence factor SrfB HI0933_like PF03486.14 ACL95010.1 - 8.4e-149 495.7 0.1 9.4e-149 495.5 0.1 1.0 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 ACL95010.1 - 3.3e-12 46.2 8.4 2.2e-09 36.9 2.8 3.2 2 1 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 ACL95010.1 - 2.6e-10 40.0 0.7 1.4e-05 24.5 0.1 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ACL95010.1 - 2.5e-09 36.8 2.2 0.00062 19.1 1.5 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ACL95010.1 - 5e-08 32.4 1.4 0.0004 19.6 0.4 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 ACL95010.1 - 6.8e-08 32.3 0.3 1e-07 31.7 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 ACL95010.1 - 1.7e-07 31.2 6.7 3.2e-05 23.7 1.2 2.6 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 ACL95010.1 - 1.7e-06 28.5 1.0 0.017 15.7 0.6 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ACL95010.1 - 2.2e-06 27.8 0.2 5.2e-06 26.6 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 ACL95010.1 - 0.00033 20.0 1.2 0.0015 17.9 1.2 1.8 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 ACL95010.1 - 0.00049 19.3 1.3 0.023 13.7 0.8 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 ACL95010.1 - 0.001 18.3 1.1 0.0032 16.8 0.3 2.0 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 ACL95010.1 - 0.015 14.6 0.1 0.022 14.1 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DEAD PF00270.29 ACL95011.1 - 3.1e-42 144.3 0.0 1.1e-40 139.2 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ACL95011.1 - 7.5e-21 74.6 0.0 1.4e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DbpA PF03880.15 ACL95011.1 - 5.7e-13 48.7 0.0 1.1e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 DbpA RNA binding domain ResIII PF04851.15 ACL95011.1 - 0.00014 21.9 0.0 0.00021 21.3 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DMRT-like PF15791.5 ACL95011.1 - 0.13 12.7 0.5 6 7.3 0.0 2.7 2 0 0 2 2 2 0 Doublesex-and mab-3-related transcription factor C1 and C2 CMS1 PF14617.6 ACL95011.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit tRNA-synt_1g PF09334.11 ACL95012.1 - 3.3e-140 467.3 0.0 3.9e-140 467.0 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 ACL95012.1 - 2e-07 29.6 1.4 0.00026 19.4 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 ACL95012.1 - 1.2e-05 25.4 0.0 2.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1f PF01921.18 ACL95012.1 - 0.049 12.5 0.1 0.49 9.2 0.1 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (K) zinc_ribbon_4 PF13717.6 ACL95012.1 - 0.1 12.5 0.3 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 ACL95012.1 - 0.25 10.8 3.9 0.77 9.2 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain MFS_1_like PF12832.7 ACL95013.1 - 1.1e-42 146.3 12.4 2.2e-42 145.3 12.4 1.4 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 ACL95013.1 - 1.4e-13 50.5 37.8 1.4e-13 50.5 37.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 ACL95013.1 - 2e-10 40.2 11.7 2.4e-10 40.0 11.7 1.0 1 0 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.19 ACL95013.1 - 2.7e-05 23.1 5.6 4.6e-05 22.4 5.6 1.3 1 1 0 1 1 1 1 LacY proton/sugar symporter APS_kinase PF01583.20 ACL95014.1 - 9.4e-74 246.6 0.0 1.7e-73 245.7 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase GTP_EFTU PF00009.27 ACL95014.1 - 1.2e-40 139.2 0.0 2.1e-40 138.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ACL95014.1 - 1.9e-07 31.2 0.2 0.00033 20.7 0.1 3.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 ACL95014.1 - 4.2e-06 27.0 0.0 4.8e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ACL95014.1 - 5.9e-06 26.3 0.0 0.033 14.1 0.0 3.5 2 1 1 3 3 3 1 RsgA GTPase GTP_EFTU_D2 PF03144.25 ACL95014.1 - 1.1e-05 25.8 0.1 3.2e-05 24.2 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 AAA_18 PF13238.6 ACL95014.1 - 6.2e-05 23.6 0.0 0.00025 21.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 ACL95014.1 - 0.00021 21.8 0.0 0.00061 20.3 0.0 1.8 2 0 0 2 2 1 1 ABC transporter CPT PF07931.12 ACL95014.1 - 0.00057 19.8 0.1 0.0036 17.2 0.1 2.2 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_29 PF13555.6 ACL95014.1 - 0.00074 19.2 0.2 0.047 13.4 0.0 2.9 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_16 PF13191.6 ACL95014.1 - 0.0015 19.0 0.0 0.0035 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 ACL95014.1 - 0.0029 16.9 0.0 0.0051 16.1 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin SRP54 PF00448.22 ACL95014.1 - 0.02 14.5 0.1 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain SRPRB PF09439.10 ACL95014.1 - 0.029 13.8 0.1 0.57 9.6 0.0 2.6 2 1 1 3 3 3 0 Signal recognition particle receptor beta subunit GTP_EFTU_D3 PF03143.17 ACL95014.1 - 0.032 14.5 0.0 0.064 13.6 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu C-terminal domain MeaB PF03308.16 ACL95014.1 - 0.033 13.2 0.1 0.099 11.6 0.0 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 ACL95014.1 - 0.041 13.6 0.0 0.14 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 ACL95014.1 - 0.041 13.6 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase AAA_22 PF13401.6 ACL95014.1 - 0.048 13.9 0.0 0.16 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 ACL95014.1 - 0.056 12.6 0.0 4.8 6.2 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Roc PF08477.13 ACL95014.1 - 0.067 13.4 0.1 31 4.8 0.0 3.1 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase KTI12 PF08433.10 ACL95014.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 PAPS_reduct PF01507.19 ACL95015.1 - 2.1e-62 210.2 0.0 2.6e-62 209.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Fib_alpha PF08702.10 ACL95017.1 - 0.31 11.2 5.0 9.7 6.4 0.0 3.3 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family AIRS PF00586.24 ACL95017.1 - 1.6 9.4 6.3 0.62 10.7 0.1 3.3 2 1 0 3 3 3 0 AIR synthase related protein, N-terminal domain ApoO PF09769.9 ACL95017.1 - 5 7.1 12.1 3.4 7.6 0.2 5.1 3 2 1 5 5 5 0 Apolipoprotein O Prominin PF05478.11 ACL95017.1 - 6.2 4.6 8.0 2.6 5.9 2.3 2.3 1 1 0 2 2 2 0 Prominin Exonuc_VII_L PF02601.15 ACL95017.1 - 7.7 6.0 31.7 0.39 10.3 6.6 3.3 1 1 1 2 2 2 0 Exonuclease VII, large subunit Bac_transf PF02397.16 ACL95018.1 - 1.8e-50 171.1 0.0 2e-50 170.9 0.0 1.0 1 0 0 1 1 1 1 Bacterial sugar transferase Mannitol_dh_C PF08125.13 ACL95019.1 - 9.3e-61 205.4 0.0 1.3e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 ACL95019.1 - 1.3e-37 129.3 0.0 2.4e-37 128.4 0.0 1.5 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain GD_AH_C PF04295.13 ACL95020.1 - 2.8e-154 513.7 0.0 3.3e-154 513.4 0.0 1.1 1 0 0 1 1 1 1 D-galactarate dehydratase / Altronate hydrolase, C terminus SAF PF08666.12 ACL95020.1 - 1.3e-09 38.6 0.6 5.4e-09 36.5 0.5 2.1 2 0 0 2 2 2 1 SAF domain Peripla_BP_3 PF13377.6 ACL95021.1 - 3.6e-40 138.0 0.0 1.6e-39 135.9 0.0 1.9 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 ACL95021.1 - 8.3e-22 77.9 0.0 1.1e-21 77.5 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 ACL95021.1 - 1.4e-20 72.8 0.1 4.1e-20 71.3 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 ACL95021.1 - 1.1e-10 41.5 0.0 1.3e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain HTH_Tnp_ISL3 PF13542.6 ACL95021.1 - 0.0018 17.6 0.2 0.0037 16.7 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 MarR_2 PF12802.7 ACL95021.1 - 0.0042 16.9 0.1 0.012 15.5 0.1 1.8 1 0 0 1 1 1 1 MarR family HTH_38 PF13936.6 ACL95021.1 - 0.011 15.5 0.5 0.065 13.0 0.5 2.3 1 0 0 1 1 1 0 Helix-turn-helix domain TetR_N PF00440.23 ACL95021.1 - 0.013 15.3 0.1 0.036 13.9 0.1 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family Peripla_BP_6 PF13458.6 ACL95021.1 - 0.013 15.1 0.0 0.032 13.9 0.0 1.6 1 1 0 1 1 1 0 Periplasmic binding protein HTH_23 PF13384.6 ACL95021.1 - 0.023 14.5 0.1 0.059 13.2 0.1 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_10 PF04967.12 ACL95021.1 - 0.03 14.1 0.1 0.073 12.9 0.1 1.6 1 0 0 1 1 1 0 HTH DNA binding domain HTH_Crp_2 PF13545.6 ACL95021.1 - 0.059 13.3 1.0 0.13 12.3 0.0 2.0 3 0 0 3 3 2 0 Crp-like helix-turn-helix domain HTH_17 PF12728.7 ACL95021.1 - 0.061 13.5 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_36 PF13730.6 ACL95021.1 - 0.077 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HHH_5 PF14520.6 ACL95021.1 - 0.095 13.3 0.0 0.26 11.9 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain HTH_29 PF13551.6 ACL95021.1 - 0.11 12.6 0.1 0.3 11.1 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn helix HTH_31 PF13560.6 ACL95021.1 - 0.11 12.8 0.1 0.28 11.5 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 ACL95021.1 - 0.17 11.5 0.2 0.39 10.3 0.2 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_7 PF02796.15 ACL95021.1 - 0.17 12.0 0.8 0.44 10.7 0.2 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase UxaC PF02614.14 ACL95022.1 - 3.8e-70 237.0 0.0 4.8e-70 236.7 0.0 1.0 1 0 0 1 1 1 1 Glucuronate isomerase KduI PF04962.12 ACL95023.1 - 7.2e-39 133.7 0.0 9e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 KduI/IolB family CdiA_C_tRNase PF18664.1 ACL95023.1 - 0.028 14.6 0.0 0.053 13.7 0.0 1.4 1 0 0 1 1 1 0 CdiA C-terminal tRNase domain adh_short_C2 PF13561.6 ACL95024.1 - 3.2e-59 200.3 3.3 3.6e-59 200.1 3.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ACL95024.1 - 5.4e-53 179.4 2.2 6.6e-53 179.1 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ACL95024.1 - 2.6e-11 43.7 0.8 3.7e-11 43.3 0.8 1.3 1 1 0 1 1 1 1 KR domain PEPcase PF00311.17 ACL95025.1 - 3e-230 766.5 0.0 3.6e-230 766.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase Aldolase PF01081.19 ACL95027.1 - 4.8e-34 117.5 0.1 5.7e-34 117.3 0.1 1.0 1 0 0 1 1 1 1 KDPG and KHG aldolase Sacchrp_dh_NADP PF03435.18 ACL95027.1 - 0.14 12.4 0.1 9 6.6 0.0 2.6 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain PfkB PF00294.24 ACL95028.1 - 1.4e-21 77.1 0.4 5.4e-21 75.2 0.4 1.9 1 1 0 1 1 1 1 pfkB family carbohydrate kinase DUF1244 PF06844.11 ACL95031.1 - 6.5e-30 103.1 0.1 8.4e-30 102.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1244) Abhydrolase_1 PF00561.20 ACL95032.1 - 4e-24 85.6 0.0 6.5e-23 81.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ACL95032.1 - 1.4e-12 47.4 0.1 8.2e-09 35.1 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ACL95032.1 - 5.6e-09 36.9 5.2 1.1e-08 36.0 5.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ACL95032.1 - 2.3e-05 24.0 0.0 0.00081 18.9 0.0 2.4 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 ACL95032.1 - 0.049 13.4 0.0 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase LIP PF03583.14 ACL95032.1 - 0.067 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Secretory lipase YqjK PF13997.6 ACL95032.1 - 0.11 12.7 0.2 0.35 11.1 0.2 1.8 1 0 0 1 1 1 0 YqjK-like protein Esterase PF00756.20 ACL95032.1 - 0.12 12.0 0.0 0.31 10.6 0.0 1.7 2 0 0 2 2 2 0 Putative esterase Peptidase_S10 PF00450.22 ACL95032.1 - 0.16 11.3 0.1 9.4 5.5 0.0 2.3 2 0 0 2 2 2 0 Serine carboxypeptidase Na_H_Exchanger PF00999.21 ACL95033.2 - 2.3e-50 171.5 43.3 3.1e-50 171.1 43.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF2417 PF10329.9 ACL95033.2 - 0.12 11.8 0.8 0.28 10.6 0.8 1.6 1 0 0 1 1 1 0 Region of unknown function (DUF2417) HTH_18 PF12833.7 ACL95034.1 - 1.8e-18 66.6 6.8 7.4e-15 55.0 1.3 3.0 2 1 1 3 3 3 2 Helix-turn-helix domain HTH_AraC PF00165.23 ACL95034.1 - 2.9e-10 40.0 0.0 0.00015 21.7 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Cupin_7 PF12973.7 ACL95034.1 - 0.0056 16.6 0.1 0.017 15.0 0.0 1.8 2 0 0 2 2 2 1 ChrR Cupin-like domain Beta-lactamase PF00144.24 ACL95035.1 - 2.5e-61 207.7 8.0 4.3e-61 207.0 8.0 1.3 1 0 0 1 1 1 1 Beta-lactamase SelB-wing_1 PF09105.10 ACL95035.1 - 0.0085 16.0 0.8 3.9 7.5 0.0 3.2 3 0 0 3 3 3 2 Elongation factor SelB, winged helix DUF3471 PF11954.8 ACL95035.1 - 0.2 12.1 0.0 0.48 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3471) ArsC PF03960.15 ACL95036.1 - 7.8e-19 67.5 0.0 9.5e-19 67.2 0.0 1.2 1 0 0 1 1 1 1 ArsC family Glutaredoxin PF00462.24 ACL95036.1 - 0.0076 16.4 0.0 0.4 10.9 0.0 2.7 2 1 1 3 3 3 1 Glutaredoxin MIP PF00230.20 ACL95037.1 - 4.4e-28 98.5 14.3 2.5e-22 79.7 6.8 2.0 1 1 1 2 2 2 2 Major intrinsic protein HTH_20 PF12840.7 ACL95038.1 - 1.1e-12 47.8 0.9 1.5e-12 47.4 0.3 1.5 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.7 ACL95038.1 - 9.6e-06 25.4 0.3 1.4e-05 24.9 0.3 1.3 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 ACL95038.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.5 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain Rrf2 PF02082.20 ACL95038.1 - 0.012 15.9 0.0 0.018 15.4 0.0 1.3 1 1 0 1 1 1 0 Transcriptional regulator HTH_5 PF01022.20 ACL95038.1 - 0.014 15.3 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family MarR PF01047.22 ACL95038.1 - 0.034 14.1 0.0 0.05 13.5 0.0 1.2 1 0 0 1 1 1 0 MarR family Fe_dep_repress PF01325.19 ACL95038.1 - 0.06 13.6 0.0 0.14 12.4 0.0 1.6 1 1 1 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain B-block_TFIIIC PF04182.12 ACL95038.1 - 0.19 11.9 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC FMN_red PF03358.15 ACL95039.1 - 3e-28 98.5 0.0 4.2e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase GSDH PF07995.11 ACL95040.1 - 1.3e-134 448.7 0.0 1.5e-134 448.5 0.0 1.0 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase NHL PF01436.21 ACL95040.1 - 5.5e-05 23.0 0.0 0.037 14.1 0.0 3.1 3 0 0 3 3 3 2 NHL repeat Tachylectin PF14517.6 ACL95040.1 - 0.0025 17.4 0.0 0.29 10.6 0.0 2.8 3 1 0 3 3 3 1 Tachylectin Reg_prop PF07494.11 ACL95040.1 - 0.034 14.4 0.1 19 5.9 0.0 3.5 3 0 0 3 3 3 0 Two component regulator propeller MFS_1 PF07690.16 ACL95041.1 - 2.6e-57 194.4 31.5 2.6e-57 194.4 31.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1440 PF07274.12 ACL95041.1 - 0.0055 17.0 4.9 0.014 15.8 0.7 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1440) DUF4381 PF14316.6 ACL95041.1 - 0.015 15.6 5.4 0.04 14.2 5.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) FAA_hydrolase PF01557.18 ACL95042.1 - 9.8e-07 28.7 0.2 1.4e-06 28.1 0.2 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF3012 PF11216.8 ACL95042.1 - 0.12 12.4 0.2 0.24 11.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3012) Penicillinase_R PF03965.16 ACL95043.1 - 2.1e-33 115.1 0.0 2.3e-33 115.0 0.0 1.0 1 0 0 1 1 1 1 Penicillinase repressor TrmB PF01978.19 ACL95043.1 - 0.038 13.9 0.0 0.093 12.6 0.0 1.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB DUF3489 PF11994.8 ACL95043.1 - 0.051 13.7 0.3 0.075 13.1 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) MarR PF01047.22 ACL95043.1 - 0.073 13.0 0.0 0.22 11.5 0.0 1.9 1 1 0 1 1 1 0 MarR family RepC PF06504.11 ACL95043.1 - 0.085 12.1 0.0 0.098 11.8 0.0 1.0 1 0 0 1 1 1 0 Replication protein C (RepC) FhuF PF06276.12 ACL95043.1 - 0.11 12.9 0.2 0.51 10.7 0.0 1.8 1 1 1 2 2 2 0 Ferric iron reductase FhuF-like transporter YkuD PF03734.14 ACL95044.1 - 6.9e-31 107.6 0.0 1.9e-30 106.2 0.0 1.7 2 0 0 2 2 2 1 L,D-transpeptidase catalytic domain PG_binding_1 PF01471.18 ACL95044.1 - 1.7e-10 41.0 0.1 1.7e-10 41.0 0.1 1.9 2 0 0 2 2 2 1 Putative peptidoglycan binding domain Peptidase_M15_2 PF05951.13 ACL95045.2 - 1.6e-69 232.4 0.0 1.9e-69 232.2 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF882) Peptidase_M15_3 PF08291.11 ACL95045.2 - 1.2e-11 44.6 0.0 1.9e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase M15 GFA PF04828.14 ACL95047.1 - 1e-11 45.0 0.3 1.3e-11 44.6 0.3 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme PBP_like_2 PF12849.7 ACL95048.1 - 4.1e-37 128.4 0.4 5.2e-37 128.0 0.4 1.0 1 0 0 1 1 1 1 PBP superfamily domain PBP_like PF12727.7 ACL95048.1 - 3.2e-05 23.1 0.4 5.3e-05 22.4 0.4 1.4 1 1 0 1 1 1 1 PBP superfamily domain Transgly PF00912.22 ACL95049.1 - 2e-61 206.6 0.0 3.2e-61 205.9 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase Transpeptidase PF00905.22 ACL95049.1 - 4.7e-20 72.0 0.0 2.9e-19 69.4 0.0 1.9 1 1 0 1 1 1 1 Penicillin binding protein transpeptidase domain TonB_dep_Rec PF00593.24 ACL95050.1 - 6.3e-59 201.1 20.7 9.9e-59 200.4 20.7 1.3 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 ACL95050.1 - 6.8e-14 52.3 3.0 1.1e-13 51.6 0.2 2.7 3 0 0 3 3 3 1 TonB-dependent Receptor Plug Domain ABC_tran PF00005.27 ACL95051.1 - 7.5e-30 104.2 0.0 9.4e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ACL95051.1 - 8.1e-15 55.4 0.0 1.3e-08 35.0 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system MeaB PF03308.16 ACL95051.1 - 0.0012 17.9 0.1 0.0022 17.0 0.1 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 ACL95051.1 - 0.0018 18.0 0.2 0.0043 16.8 0.2 1.6 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 ACL95051.1 - 0.0045 16.4 0.0 1.4 8.3 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ACL95051.1 - 0.0088 15.8 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 ACL95051.1 - 0.034 13.9 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein MukB PF04310.12 ACL95051.1 - 0.038 13.8 0.0 0.059 13.2 0.0 1.2 1 0 0 1 1 1 0 MukB N-terminal T2SSE PF00437.20 ACL95051.1 - 0.041 12.9 0.0 0.064 12.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 ACL95051.1 - 0.044 14.3 0.3 0.07 13.6 0.3 1.2 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 ACL95051.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 ACL95051.1 - 0.17 12.2 0.1 0.35 11.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain DUF3526 PF12040.8 ACL95052.1 - 1.4e-50 171.8 6.5 1e-49 169.0 3.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3526) ABC2_membrane_2 PF12679.7 ACL95052.1 - 2.2e-19 69.8 4.3 4.8e-19 68.7 4.3 1.6 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 ACL95052.1 - 2e-07 30.5 5.7 3.9e-07 29.5 5.7 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 ACL95052.1 - 5.6e-05 23.2 0.5 0.00042 20.3 0.7 2.0 2 0 0 2 2 2 1 ABC-2 family transporter protein OppC_N PF12911.7 ACL95052.1 - 0.15 12.1 0.0 0.15 12.1 0.0 3.3 3 1 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C DUF3526 PF12040.8 ACL95053.1 - 3.1e-34 118.7 3.8 4.4e-34 118.2 3.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3526) YwiC PF14256.6 ACL95053.1 - 1.2 9.4 23.5 0.13 12.6 14.7 3.2 3 0 0 3 3 3 0 YwiC-like protein Acyl_transf_3 PF01757.22 ACL95054.1 - 1e-23 83.9 36.5 1.4e-23 83.6 36.5 1.1 1 0 0 1 1 1 1 Acyltransferase family MHYT PF03707.16 ACL95054.1 - 2.3 8.4 0.0 2.3 8.4 0.0 4.3 4 1 0 4 4 4 0 Bacterial signalling protein N terminal repeat DNA_ligase_aden PF01653.18 ACL95055.1 - 4.3e-112 374.3 0.0 6.1e-112 373.8 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 ACL95055.1 - 2.7e-34 116.9 3.4 5.3e-34 116.0 3.4 1.5 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain HHH_2 PF12826.7 ACL95055.1 - 1.2e-12 47.8 0.3 5.6e-05 23.2 0.0 4.1 3 2 0 3 3 3 2 Helix-hairpin-helix motif BRCT PF00533.26 ACL95055.1 - 5.3e-12 45.9 0.0 9.3e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain HHH_5 PF14520.6 ACL95055.1 - 1.1e-07 32.3 1.8 0.12 13.0 0.1 4.6 4 1 0 4 4 4 2 Helix-hairpin-helix domain PTCB-BRCT PF12738.7 ACL95055.1 - 0.0015 18.4 0.0 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain HHH PF00633.23 ACL95055.1 - 0.019 14.8 1.1 9.1 6.4 0.0 3.5 3 0 0 3 3 3 0 Helix-hairpin-helix motif Bep_C_terminal PF17841.1 ACL95055.1 - 0.099 12.9 0.1 0.29 11.4 0.1 1.8 1 0 0 1 1 1 0 BID domain of Bartonella effector protein (Bep) RNase_T PF00929.24 ACL95056.1 - 7.4e-18 65.6 0.0 9.2e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 ACL95056.1 - 4.3e-05 23.6 0.0 0.00045 20.3 0.0 2.0 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like DNA_pol_A_exo1 PF01612.20 ACL95056.1 - 0.034 13.8 0.0 0.24 11.1 0.0 2.1 1 1 0 1 1 1 0 3'-5' exonuclease DUF2147 PF09917.9 ACL95057.1 - 6.5e-28 97.6 0.3 7.6e-28 97.4 0.3 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2147) Peptidase_M24 PF00557.24 ACL95058.1 - 1.4e-44 152.3 0.5 2e-44 151.8 0.0 1.5 2 0 0 2 2 2 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 ACL95058.1 - 7.7e-34 117.1 0.0 1.7e-33 116.0 0.0 1.6 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 ACL95058.1 - 1.5e-20 73.0 0.0 2.8e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 ACL95058.1 - 2.1e-17 64.0 0.0 4.4e-13 50.0 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain PGM1_C PF18105.1 ACL95058.1 - 0.35 10.4 2.7 0.42 10.2 0.1 2.5 3 0 0 3 3 3 0 PGM1 C-terminal domain PrmA PF06325.13 ACL95059.1 - 3.4e-66 223.7 0.0 3.8e-66 223.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 ACL95059.1 - 4.2e-11 43.4 0.0 7.1e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ACL95059.1 - 3.3e-09 36.5 0.0 5.1e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 ACL95059.1 - 1.1e-07 31.8 0.0 1.7e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ACL95059.1 - 1.9e-07 31.6 0.0 3.4e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ACL95059.1 - 2.3e-06 27.5 0.0 3.9e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ACL95059.1 - 2.2e-05 25.1 0.0 7.2e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 ACL95059.1 - 6.8e-05 22.7 0.0 9.1e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 ACL95059.1 - 0.00031 20.5 0.0 0.00043 20.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Cons_hypoth95 PF03602.15 ACL95059.1 - 0.00043 20.0 0.1 0.0027 17.4 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Met_10 PF02475.16 ACL95059.1 - 0.0017 18.1 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Ubie_methyltran PF01209.18 ACL95059.1 - 0.033 13.5 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 ACL95059.1 - 0.037 13.0 0.0 0.31 9.9 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 ACL95059.1 - 0.044 13.7 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain UvrD-helicase PF00580.21 ACL95061.2 - 2.4e-74 250.7 0.0 6.8e-74 249.2 0.0 1.8 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 ACL95061.2 - 1.6e-59 202.1 0.0 6.4e-59 200.1 0.0 1.8 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 ACL95061.2 - 2.4e-31 109.1 0.0 4.9e-31 108.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 ACL95061.2 - 3.7e-10 39.5 0.0 1.8e-09 37.3 0.0 2.2 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 ACL95061.2 - 3.7e-10 39.8 0.0 3.8e-06 26.8 0.1 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 ACL95061.2 - 0.00095 19.0 0.0 4.6 6.9 0.0 3.5 3 1 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DUF3553 PF12073.8 ACL95061.2 - 0.0021 17.7 0.2 0.0044 16.7 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3553) AAA_11 PF13086.6 ACL95061.2 - 0.049 13.4 0.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 ACL95061.2 - 0.13 12.5 0.1 0.57 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 ACL95061.2 - 0.22 11.9 1.2 0.71 10.2 0.2 2.4 2 1 0 2 2 2 0 AAA ATPase domain RHH_4 PF13467.6 ACL95062.1 - 5.5e-22 77.4 0.0 6.5e-22 77.2 0.0 1.1 1 0 0 1 1 1 1 Ribbon-helix-helix domain Trp_halogenase PF04820.14 ACL95063.1 - 6.1e-182 605.5 0.0 7.2e-182 605.3 0.0 1.0 1 0 0 1 1 1 1 Tryptophan halogenase DAO PF01266.24 ACL95063.1 - 0.0045 16.6 5.1 0.062 12.9 5.1 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ACL95063.1 - 0.0063 15.9 2.0 0.9 8.8 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ACL95063.1 - 0.011 15.7 0.5 4.8 7.2 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 ACL95063.1 - 0.046 12.9 1.2 0.65 9.2 1.3 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ACL95063.1 - 0.14 12.4 2.3 0.39 11.0 2.3 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ACL95063.1 - 0.18 10.5 1.6 0.25 10.0 1.6 1.1 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 ACL95063.1 - 0.36 11.4 4.0 0.78 10.3 2.3 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ACL95063.1 - 0.43 9.6 1.9 15 4.5 0.0 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein DUF4169 PF13770.6 ACL95064.1 - 1e-21 76.9 13.8 1.1e-21 76.8 13.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4169) PmoA PF14100.6 ACL95065.1 - 1.4e-29 103.5 0.0 1.6e-29 103.2 0.0 1.0 1 0 0 1 1 1 1 Methane oxygenase PmoA DUF4115 PF13464.6 ACL95065.1 - 0.2 11.8 1.7 14 6.0 0.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4115) SPDY PF03771.16 ACL95065.1 - 0.41 10.6 6.9 0.12 12.3 2.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF317) DUF2171 PF09939.9 ACL95066.1 - 1.7e-25 89.1 2.2 1.9e-25 88.9 2.2 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2171) PRC PF05239.16 ACL95066.1 - 0.00087 19.3 0.1 0.00095 19.2 0.1 1.1 1 0 0 1 1 1 1 PRC-barrel domain GST_C PF00043.25 ACL95067.1 - 5.2e-11 42.6 0.0 7.8e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ACL95067.1 - 2.3e-10 40.7 0.0 4.8e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ACL95067.1 - 3.3e-09 36.7 1.9 5.2e-08 32.8 0.1 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ACL95067.1 - 1.2e-07 31.8 0.0 1.8e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ACL95067.1 - 2.4e-07 31.0 0.0 5.6e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ACL95067.1 - 8.5e-07 29.3 0.0 1.6e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 ACL95067.1 - 0.041 13.7 0.1 0.23 11.3 0.1 2.2 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Aminotran_1_2 PF00155.21 ACL95068.1 - 6.1e-78 262.5 0.0 6.9e-78 262.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 ACL95068.1 - 7.5e-08 32.1 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 ACL95068.1 - 0.026 13.1 0.0 0.044 12.3 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 ACL95068.1 - 0.11 11.5 0.0 0.21 10.5 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V CBM_4_9 PF02018.17 ACL95069.1 - 1.9e-05 25.0 0.1 2.5e-05 24.6 0.1 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain FMN_red PF03358.15 ACL95070.1 - 6.7e-35 120.1 0.0 8.1e-35 119.9 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 ACL95070.1 - 8.9e-08 32.1 0.0 1.2e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold DUF748 PF05359.11 ACL95070.1 - 0.039 14.1 0.0 0.07 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF748) Adeno_PX PF05829.12 ACL95070.1 - 0.15 11.9 0.1 0.15 11.9 0.1 1.9 2 0 0 2 2 2 0 Adenovirus late L2 mu core protein (Protein X) AAA_31 PF13614.6 ACL95071.1 - 5.2e-15 55.8 0.7 2.2e-11 44.0 0.1 2.1 1 1 1 2 2 2 2 AAA domain CbiA PF01656.23 ACL95071.1 - 3.2e-12 46.6 0.0 3.7e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 ACL95071.1 - 3.5e-08 33.2 0.3 1.3e-05 24.7 0.1 2.2 2 0 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase ArsA_ATPase PF02374.15 ACL95071.1 - 4.7e-07 29.3 0.4 2.1e-06 27.1 0.1 2.0 1 1 1 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 ACL95071.1 - 2.5e-06 27.0 1.7 0.026 13.8 0.1 2.2 1 1 0 2 2 2 2 ATPase MipZ CBP_BcsQ PF06564.12 ACL95071.1 - 8.2e-05 22.2 1.6 0.12 11.8 0.2 2.8 1 1 0 2 2 2 2 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 ACL95071.1 - 0.078 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family GFO_IDH_MocA PF01408.22 ACL95071.1 - 0.095 13.5 0.0 0.23 12.3 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold SRP54 PF00448.22 ACL95071.1 - 0.13 11.9 0.2 0.24 11.0 0.2 1.4 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain SNARE_assoc PF09335.11 ACL95072.1 - 2.8e-27 95.6 9.9 2.8e-27 95.6 9.9 2.4 3 1 1 4 4 4 1 SNARE associated Golgi protein DUF418 PF04235.12 ACL95072.1 - 2.9 7.8 19.0 0.49 10.3 2.2 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF418) TetR_N PF00440.23 ACL95073.1 - 4.2e-13 48.9 0.1 7.6e-13 48.0 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family NIR_SIR PF01077.22 ACL95073.1 - 0.058 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain Alkyl_sulf_dimr PF14863.6 ACL95074.1 - 3.7e-57 192.7 1.2 3.2e-56 189.6 0.5 2.3 2 0 0 2 2 2 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.27 ACL95074.1 - 2.6e-48 164.7 0.1 4.4e-48 163.9 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Alkyl_sulf_C PF14864.6 ACL95074.1 - 1.1e-30 106.4 0.0 3e-30 105.1 0.0 1.7 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B_2 PF12706.7 ACL95074.1 - 1.4e-07 31.3 0.0 2.9e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain SCP2 PF02036.17 ACL95074.1 - 5.8e-05 23.5 0.0 0.00031 21.2 0.0 2.0 2 0 0 2 2 2 1 SCP-2 sterol transfer family HMGL-like PF00682.19 ACL95075.1 - 1.8e-91 306.4 0.8 3.4e-91 305.5 0.8 1.5 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 ACL95075.1 - 3.5e-35 120.8 1.9 7.4e-35 119.7 1.9 1.6 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain DUF881 PF05949.12 ACL95075.1 - 0.0095 15.8 0.0 0.033 14.0 0.0 1.8 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF881) EamA PF00892.20 ACL95076.1 - 1.1e-09 38.6 34.6 2.7e-05 24.3 9.3 2.1 2 0 0 2 2 2 2 EamA-like transporter family MreB_Mbl PF06723.13 ACL95077.1 - 3.4e-150 499.4 6.7 3.9e-150 499.2 6.7 1.0 1 0 0 1 1 1 1 MreB/Mbl protein HSP70 PF00012.20 ACL95077.1 - 1.7e-12 46.3 0.1 3.4e-12 45.4 0.1 1.4 1 1 0 1 1 1 1 Hsp70 protein Actin PF00022.19 ACL95077.1 - 1.6e-10 40.2 0.0 1.1e-07 30.8 0.0 2.2 2 1 0 2 2 2 2 Actin PilM_2 PF11104.8 ACL95077.1 - 4.5e-10 39.1 0.1 0.0037 16.4 0.0 3.1 3 0 0 3 3 3 3 Type IV pilus assembly protein PilM; FtsA PF14450.6 ACL95077.1 - 6.2e-10 39.4 1.6 1.1e-09 38.6 0.2 2.0 2 1 0 2 2 2 1 Cell division protein FtsA EutA PF06277.11 ACL95077.1 - 0.0066 15.3 0.6 0.026 13.4 0.1 2.0 2 0 0 2 2 2 1 Ethanolamine utilisation protein EutA StbA PF06406.11 ACL95077.1 - 0.043 13.1 0.2 0.23 10.6 0.2 1.9 1 1 0 1 1 1 0 StbA protein Ppx-GppA PF02541.16 ACL95077.1 - 0.13 11.6 1.8 0.22 10.9 1.5 1.6 1 1 0 1 1 1 0 Ppx/GppA phosphatase family MreC PF04085.14 ACL95078.1 - 5.1e-27 94.6 0.1 7.9e-27 94.0 0.1 1.2 1 0 0 1 1 1 1 rod shape-determining protein MreC DUF4229 PF14012.6 ACL95078.1 - 0.0039 17.3 1.0 0.007 16.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) LRR19-TM PF15176.6 ACL95079.1 - 0.59 10.2 1.7 0.75 9.8 0.9 1.6 1 1 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF2070 PF09843.9 ACL95079.1 - 6.1 5.0 9.3 7.9 4.6 9.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Transpeptidase PF00905.22 ACL95080.1 - 3.9e-68 229.9 0.0 4.9e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain PBP_dimer PF03717.15 ACL95080.1 - 2.1e-39 135.7 0.0 3.4e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 Penicillin-binding Protein dimerisation domain FTSW_RODA_SPOVE PF01098.19 ACL95081.1 - 1.3e-97 327.0 25.6 1.7e-97 326.6 25.6 1.1 1 0 0 1 1 1 1 Cell cycle protein Acetyltransf_3 PF13302.7 ACL95082.1 - 5.6e-22 78.9 0.0 6.7e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ACL95082.1 - 0.0033 17.6 0.0 0.0044 17.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 ACL95082.1 - 0.03 14.0 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain UDG PF03167.19 ACL95083.1 - 2.1e-29 102.5 0.0 2.4e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF4918 PF16265.5 ACL95083.1 - 0.0018 17.8 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4918) NYN PF01936.18 ACL95084.1 - 3.1e-39 134.8 0.1 4e-39 134.4 0.1 1.0 1 0 0 1 1 1 1 NYN domain HPPK PF01288.20 ACL95085.1 - 1.9e-28 99.2 0.0 2.3e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) RNA_pol_Rpb6 PF01192.22 ACL95086.1 - 1.8e-12 47.0 0.0 5.1e-12 45.5 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb6 HD_4 PF13328.6 ACL95087.1 - 1.6e-44 151.4 0.6 2.6e-44 150.7 0.6 1.4 1 0 0 1 1 1 1 HD domain RelA_SpoT PF04607.17 ACL95087.1 - 8.2e-36 122.8 0.1 1.6e-35 121.9 0.1 1.5 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins TGS PF02824.21 ACL95087.1 - 9.7e-20 70.4 0.0 2e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 TGS domain ACT_4 PF13291.6 ACL95087.1 - 2.1e-17 63.4 0.0 4.9e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 ACT domain HD PF01966.22 ACL95087.1 - 1.5e-08 34.9 0.8 3.9e-08 33.6 0.8 1.8 1 0 0 1 1 1 1 HD domain ACT PF01842.25 ACL95087.1 - 0.00062 19.5 0.3 0.0024 17.6 0.1 2.2 2 0 0 2 2 2 1 ACT domain HTH_15 PF12324.8 ACL95087.1 - 0.052 13.5 0.6 0.89 9.6 0.2 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase NUDIX PF00293.28 ACL95088.1 - 8.5e-23 80.8 0.4 9.9e-23 80.6 0.4 1.0 1 0 0 1 1 1 1 NUDIX domain Pribosyltran PF00156.27 ACL95089.1 - 3.2e-16 59.3 0.4 6.5e-16 58.2 0.4 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain LTD PF00932.19 ACL95089.1 - 0.14 12.5 0.0 0.2 12.0 0.0 1.2 1 0 0 1 1 1 0 Lamin Tail Domain M20_dimer PF07687.14 ACL95090.1 - 2e-08 34.1 0.1 7.9e-08 32.2 0.0 2.0 2 0 0 2 2 2 1 Peptidase dimerisation domain PdxJ PF03740.13 ACL95091.1 - 2.3e-95 318.2 1.3 2.6e-95 318.0 1.3 1.0 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthesis protein PdxJ BKACE PF05853.12 ACL95091.1 - 0.00024 20.5 0.7 0.00024 20.5 0.7 1.9 2 0 0 2 2 2 1 beta-keto acid cleavage enzyme ACPS PF01648.20 ACL95092.1 - 3.5e-17 62.6 0.0 3.9e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily YCII PF03795.14 ACL95093.1 - 0.00046 20.5 0.1 0.00056 20.3 0.1 1.1 1 0 0 1 1 1 1 YCII-related domain Spore_SspJ PF09575.10 ACL95093.1 - 0.1 13.0 0.0 0.16 12.4 0.0 1.2 1 0 0 1 1 1 0 Small spore protein J (Spore_SspJ) Peptidase_S24 PF00717.23 ACL95094.1 - 4.2e-23 81.1 0.2 6.4e-23 80.5 0.2 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 ACL95094.1 - 1.7e-05 24.7 0.2 0.028 14.2 0.0 3.2 3 1 0 3 3 3 2 Signal peptidase, peptidase S26 Ribonucleas_3_3 PF14622.6 ACL95095.1 - 2.7e-27 95.5 0.0 3.9e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 ACL95095.1 - 2.2e-15 57.1 0.0 3.6e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 ACL95095.1 - 2.3e-13 50.7 0.0 3.8e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease III domain DND1_DSRM PF14709.7 ACL95095.1 - 0.0024 18.1 0.0 0.0062 16.8 0.0 1.7 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 FANCM-MHF_bd PF16783.5 ACL95095.1 - 0.16 12.1 0.0 0.26 11.4 0.0 1.2 1 0 0 1 1 1 0 FANCM to MHF binding domain TAT_ubiq PF07706.12 ACL95095.1 - 0.17 12.1 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase ubiquitination site MMR_HSR1 PF01926.23 ACL95098.1 - 3.3e-23 81.9 0.0 6.3e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase KH_2 PF07650.17 ACL95098.1 - 3.8e-18 65.1 0.3 1.1e-17 63.6 0.3 1.8 1 0 0 1 1 1 1 KH domain FeoB_N PF02421.18 ACL95098.1 - 3.3e-11 43.0 0.1 1.1e-07 31.5 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 ACL95098.1 - 1.1e-07 31.9 0.5 0.0025 17.7 0.2 2.3 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 ACL95098.1 - 1.8e-07 31.4 0.1 0.00089 19.4 0.1 2.4 2 0 0 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 ACL95098.1 - 2.3e-05 24.0 0.3 0.052 13.1 0.4 3.0 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 ACL95098.1 - 9.4e-05 21.8 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 AIG1 family PduV-EutP PF10662.9 ACL95098.1 - 0.00015 21.5 0.0 0.065 13.0 0.0 3.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 ACL95098.1 - 0.00016 21.3 0.1 0.0094 15.6 0.0 2.3 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1_Xtn PF16897.5 ACL95098.1 - 0.0017 18.4 0.0 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Arf PF00025.21 ACL95098.1 - 0.0064 16.0 0.1 0.018 14.5 0.1 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_28 PF13521.6 ACL95098.1 - 0.025 14.8 0.8 0.58 10.4 0.0 2.8 2 1 0 3 3 3 0 AAA domain AAA_22 PF13401.6 ACL95098.1 - 0.032 14.5 0.0 0.078 13.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ACL95098.1 - 0.045 14.1 0.2 0.12 12.8 0.1 1.8 2 0 0 2 2 2 0 AAA ATPase domain SRPRB PF09439.10 ACL95098.1 - 0.064 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Roc PF08477.13 ACL95098.1 - 0.1 12.8 0.0 0.39 11.0 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 ACL95098.1 - 0.12 12.1 0.1 0.34 10.7 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 ACL95098.1 - 0.45 10.0 3.6 1.8 8.1 0.9 2.5 2 1 0 2 2 2 0 AAA domain Acetyltransf_2 PF00797.17 ACL95099.1 - 1.2e-79 267.5 0.0 1.3e-79 267.3 0.0 1.0 1 0 0 1 1 1 1 N-acetyltransferase RecO_C PF02565.15 ACL95100.1 - 1.5e-23 83.3 0.1 2.1e-23 82.9 0.1 1.2 1 0 0 1 1 1 1 Recombination protein O C terminal RecO_N PF11967.8 ACL95100.1 - 3.4e-14 52.6 0.0 5.6e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Recombination protein O N terminal PhoD PF09423.10 ACL95101.1 - 1.5e-109 366.2 2.2 1.9e-109 365.9 2.2 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 ACL95101.1 - 1.9e-30 105.3 0.0 3.5e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 ACL95101.1 - 0.0099 16.4 0.0 0.021 15.4 0.0 1.5 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 ACL95101.1 - 0.048 14.2 0.4 0.18 12.3 0.2 1.9 1 1 1 2 2 2 0 Calcineurin-like phosphoesterase DNA_topoisoIV PF00521.20 ACL95102.1 - 2e-139 465.2 0.0 2.5e-139 464.9 0.0 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 ACL95102.1 - 5.9e-14 51.3 2.1 1.5e-06 27.6 0.0 4.8 5 0 0 5 5 5 3 DNA gyrase C-terminal domain, beta-propeller Beta-lactamase PF00144.24 ACL95103.1 - 2e-74 250.8 4.3 2.9e-74 250.3 4.3 1.2 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase PF00144.24 ACL95104.1 - 3.2e-77 260.0 0.2 4.1e-77 259.6 0.2 1.1 1 0 0 1 1 1 1 Beta-lactamase ADH_zinc_N PF00107.26 ACL95105.1 - 3.7e-29 101.3 1.5 4e-29 101.2 0.4 1.7 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ACL95105.1 - 3.9e-23 83.0 0.2 8.2e-23 81.9 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ACL95105.1 - 3.9e-08 33.2 1.5 9.5e-08 31.9 1.5 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 ACL95105.1 - 6.9e-05 22.2 2.8 0.00011 21.5 0.4 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NMO PF03060.15 ACL95106.1 - 1.5e-52 179.0 6.2 5e-39 134.6 3.0 2.2 1 1 1 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 ACL95106.1 - 1.5e-13 50.5 0.2 1.4e-05 24.2 0.4 2.3 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 ACL95106.1 - 8.4e-10 38.2 5.4 1e-09 37.9 3.8 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase ThiG PF05690.14 ACL95106.1 - 0.0003 20.2 2.8 0.00065 19.1 2.8 1.6 1 1 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 ACL95106.1 - 0.00086 18.8 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein Glu_synthase PF01645.17 ACL95106.1 - 0.0029 16.8 0.3 0.0029 16.8 0.3 2.1 1 1 1 2 2 2 1 Conserved region in glutamate synthase DHO_dh PF01180.21 ACL95106.1 - 0.068 12.4 0.1 0.12 11.5 0.1 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase G3P_antiterm PF04309.12 ACL95106.1 - 0.11 11.9 0.0 0.26 10.7 0.0 1.6 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator Oxidored_FMN PF00724.20 ACL95106.1 - 0.14 11.4 0.4 4.5 6.4 0.4 2.1 2 0 0 2 2 2 0 NADH:flavin oxidoreductase / NADH oxidase family adh_short_C2 PF13561.6 ACL95107.1 - 8.3e-47 159.7 3.1 9.8e-47 159.5 3.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ACL95107.1 - 1.7e-45 154.9 0.1 2.3e-45 154.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ACL95107.1 - 1.5e-09 38.0 0.1 2.5e-09 37.3 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ACL95107.1 - 0.15 11.5 0.8 0.79 9.1 0.8 2.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 ACL95107.1 - 0.27 10.5 0.0 0.38 10.1 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ATE_C PF04377.15 ACL95108.1 - 1.3e-31 110.0 0.0 1.7e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 ACL95108.1 - 1.2e-13 51.2 0.1 2.5e-13 50.2 0.1 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.7 ACL95108.1 - 0.11 12.6 0.6 0.17 12.0 0.6 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MotB_plug PF13677.6 ACL95109.1 - 6.6e-20 70.5 1.3 3.3e-19 68.2 0.0 2.3 2 0 0 2 2 2 1 Membrane MotB of proton-channel complex MotA/MotB OmpA PF00691.20 ACL95109.1 - 2.4e-12 47.1 1.1 3.4e-12 46.6 0.1 1.8 2 0 0 2 2 2 1 OmpA family DUF3323 PF11796.8 ACL95109.1 - 0.22 11.4 7.9 0.21 11.4 1.4 2.7 1 1 1 3 3 3 0 Protein of unknown function N-terminus (DUF3323) DUF5521 PF17659.1 ACL95109.1 - 0.84 7.4 1.8 1 7.1 1.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) NAD_binding_2 PF03446.15 ACL95110.1 - 2.8e-49 167.3 3.9 4.5e-49 166.7 3.9 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ACL95110.1 - 1.9e-33 115.3 1.8 2.3e-33 115.0 0.4 1.8 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 ACL95110.1 - 4.6e-13 49.6 0.1 9.7e-13 48.5 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.17 ACL95110.1 - 4.2e-08 32.5 0.2 6e-08 32.0 0.2 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase 2-Hacid_dh_C PF02826.19 ACL95110.1 - 7.9e-07 28.6 0.1 1.4e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 ACL95110.1 - 8.9e-07 29.1 0.0 1.8e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.22 ACL95110.1 - 0.00011 23.0 1.1 0.00016 22.4 0.4 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold 3HCDH_N PF02737.18 ACL95110.1 - 0.00015 21.7 0.5 0.0016 18.3 0.1 2.4 1 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 ACL95110.1 - 0.00018 21.2 0.1 0.0003 20.4 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_10 PF13460.6 ACL95110.1 - 0.00018 21.4 0.9 0.00038 20.4 0.9 1.6 1 0 0 1 1 1 1 NAD(P)H-binding ApbA PF02558.16 ACL95110.1 - 0.002 17.8 0.1 0.0047 16.6 0.1 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Rossmann-like PF10727.9 ACL95110.1 - 0.0037 17.1 1.6 0.0037 17.1 1.6 1.9 2 0 0 2 2 2 1 Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 ACL95110.1 - 0.0077 15.8 0.0 0.29 10.7 0.0 2.4 1 1 1 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 ACL95110.1 - 0.012 15.6 0.1 0.098 12.6 0.2 2.5 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sacchrp_dh_NADP PF03435.18 ACL95110.1 - 0.019 15.2 0.0 0.2 11.9 0.0 2.1 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_C PF03720.15 ACL95110.1 - 0.032 14.7 0.0 0.054 13.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Pyr_redox PF00070.27 ACL95110.1 - 0.052 14.1 0.1 0.097 13.2 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AAA_26 PF13500.6 ACL95111.1 - 1.4e-33 116.5 0.0 1.6e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 ACL95111.1 - 0.0026 17.8 0.0 0.0036 17.3 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.14 ACL95111.1 - 0.0057 16.6 0.0 0.092 12.6 0.0 2.2 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF1611 PF07755.11 ACL95111.1 - 0.036 13.4 0.2 0.11 11.7 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_C) P-loop domain Aminotran_1_2 PF00155.21 ACL95112.1 - 2.5e-56 191.4 0.0 2.8e-56 191.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 ACL95112.1 - 7.2e-07 28.8 0.2 1.2e-06 28.1 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 ACL95112.1 - 5.5e-05 22.6 0.0 0.00017 21.0 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 ACL95112.1 - 0.00017 20.7 0.0 0.00023 20.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 ACL95112.1 - 0.00071 18.2 0.0 0.00094 17.8 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.21 ACL95113.1 - 2.9e-118 395.0 0.0 3.3e-118 394.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 ACL95113.1 - 0.00043 19.6 0.0 0.00061 19.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ACL95113.1 - 0.0062 15.9 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DUF3320 PF11784.8 ACL95113.1 - 0.4 10.7 1.8 3 7.9 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3320) EamA PF00892.20 ACL95114.1 - 6.3e-28 97.7 38.1 1.6e-17 64.0 14.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family Sod_Cu PF00080.20 ACL95115.1 - 1.7e-36 125.5 1.5 2.1e-36 125.2 1.5 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DNA_topoisoIV PF00521.20 ACL95116.1 - 2.9e-144 481.1 0.0 3.5e-144 480.9 0.0 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 ACL95116.1 - 7.1e-70 230.3 13.3 8.3e-13 47.6 0.1 6.6 6 0 0 6 6 6 6 DNA gyrase C-terminal domain, beta-propeller CTP_transf_like PF01467.26 ACL95117.1 - 6.2e-18 65.4 0.0 7.2e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like Citrate_ly_lig PF08218.11 ACL95117.1 - 0.048 13.3 0.0 0.12 12.1 0.0 1.5 1 1 0 1 1 1 0 Citrate lyase ligase C-terminal domain Pro_isomerase PF00160.21 ACL95118.1 - 2.1e-41 141.9 0.0 2.8e-41 141.4 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.21 ACL95119.1 - 3.2e-40 138.0 0.0 5.5e-40 137.2 0.0 1.4 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.21 ACL95120.1 - 1.2e-45 155.6 0.0 1.4e-45 155.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Exo_endo_phos PF03372.23 ACL95121.1 - 3.3e-11 43.1 0.0 4.5e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 ACL95121.1 - 0.007 16.2 0.0 0.026 14.4 0.0 1.8 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Queuosine_synth PF02547.15 ACL95123.1 - 4.2e-127 423.8 0.0 4.8e-127 423.6 0.0 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein MS_channel PF00924.18 ACL95123.1 - 0.28 10.7 0.0 0.42 10.1 0.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel TGT PF01702.18 ACL95124.1 - 7.6e-141 469.3 0.0 9.3e-141 469.0 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase KdpA PF03814.15 ACL95128.1 - 6.2e-220 731.0 32.6 7.1e-220 730.8 32.6 1.0 1 0 0 1 1 1 1 Potassium-transporting ATPase A subunit Hydrolase PF00702.26 ACL95129.1 - 5.4e-34 118.3 1.3 1.1e-33 117.3 1.3 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 ACL95129.1 - 9.9e-30 103.4 3.3 9.9e-30 103.4 3.3 3.1 3 0 0 3 3 3 1 E1-E2 ATPase HAD PF12710.7 ACL95129.1 - 0.00089 19.7 0.0 0.0058 17.1 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ACL95129.1 - 0.0037 17.0 0.1 0.0082 15.9 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF759 PF05537.11 ACL95129.1 - 0.041 12.8 0.0 0.059 12.3 0.0 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) CBS PF00571.28 ACL95129.1 - 0.091 13.2 0.1 0.26 11.8 0.1 1.7 1 0 0 1 1 1 0 CBS domain FA_desaturase PF00487.24 ACL95129.1 - 2.6 7.8 3.7 4.3 7.1 0.5 2.2 2 0 0 2 2 2 0 Fatty acid desaturase KdpC PF02669.15 ACL95130.1 - 5.1e-72 241.5 0.1 5.7e-72 241.4 0.1 1.0 1 0 0 1 1 1 1 K+-transporting ATPase, c chain KdpD PF02702.17 ACL95131.1 - 3.2e-95 317.6 0.5 5.1e-95 316.9 0.5 1.3 1 0 0 1 1 1 1 Osmosensitive K+ channel His kinase sensor domain DUF4118 PF13493.6 ACL95131.1 - 9.5e-23 80.0 9.1 2e-22 79.0 9.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4118) HATPase_c PF02518.26 ACL95131.1 - 1.3e-19 70.8 0.0 2.3e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ACL95131.1 - 7.3e-14 51.6 0.6 3e-13 49.6 0.1 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 ACL95131.1 - 0.0023 17.9 0.0 0.0065 16.4 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 ACL95131.1 - 0.0044 16.9 0.0 0.0074 16.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Usp PF00582.26 ACL95131.1 - 0.0079 16.7 2.3 0.0079 16.7 2.3 3.5 3 2 0 3 3 3 1 Universal stress protein family HATPase_c_5 PF14501.6 ACL95131.1 - 0.063 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 GHKL domain ResIII PF04851.15 ACL95131.1 - 0.2 11.6 0.0 0.61 10.1 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Trans_reg_C PF00486.28 ACL95132.1 - 6e-22 77.5 0.1 1.4e-21 76.3 0.0 1.6 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 ACL95132.1 - 3.1e-21 75.6 0.0 4.7e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain BPD_transp_1 PF00528.22 ACL95133.1 - 3.3e-18 66.1 21.8 3.3e-18 66.1 21.8 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component BPD_transp_1 PF00528.22 ACL95134.1 - 2e-11 43.9 10.6 2e-11 43.9 10.6 2.1 1 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component ABC_tran PF00005.27 ACL95135.1 - 5.6e-35 120.8 0.0 9e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ACL95135.1 - 4.4e-11 43.1 0.3 3.7e-05 23.7 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system CysA_C_terminal PF17850.1 ACL95135.1 - 1.5e-10 41.4 0.5 6.8e-10 39.4 0.1 2.3 2 0 0 2 2 2 1 CysA C-terminal regulatory domain SMC_N PF02463.19 ACL95135.1 - 2e-05 24.2 0.0 7.2e-05 22.3 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ACL95135.1 - 0.00011 22.6 2.0 0.00016 22.1 0.4 2.1 2 1 1 3 3 3 1 AAA ATPase domain AAA PF00004.29 ACL95135.1 - 0.0007 20.0 0.0 0.033 14.6 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ACL95135.1 - 0.00073 19.8 0.2 0.0055 17.0 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ACL95135.1 - 0.0014 18.3 0.0 0.0033 17.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 ACL95135.1 - 0.009 15.7 0.3 0.062 13.0 0.1 2.1 1 1 0 2 2 2 1 AAA domain NACHT PF05729.12 ACL95135.1 - 0.01 15.8 0.1 0.02 14.8 0.1 1.5 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 ACL95135.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 ACL95135.1 - 0.021 14.4 1.6 0.17 11.4 0.2 2.3 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 ACL95135.1 - 0.022 14.7 0.1 1.1 9.1 0.1 2.3 1 1 0 1 1 1 0 NTPase AAA_23 PF13476.6 ACL95135.1 - 0.026 15.1 0.0 0.047 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 ACL95135.1 - 0.033 13.6 0.0 0.3 10.4 0.0 2.3 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 ACL95135.1 - 0.034 13.9 0.1 0.29 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ACL95135.1 - 0.043 14.0 0.1 0.16 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 ACL95135.1 - 0.047 13.9 0.6 0.69 10.2 0.1 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Acetyltransf_6 PF13480.7 ACL95135.1 - 0.054 13.7 1.4 0.21 11.8 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain ABC_ATPase PF09818.9 ACL95135.1 - 0.073 11.8 0.1 2.5 6.8 0.0 2.7 2 1 0 2 2 2 0 Predicted ATPase of the ABC class cobW PF02492.19 ACL95135.1 - 0.097 12.3 0.1 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 ACL95135.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 ACL95135.1 - 0.11 12.4 0.1 0.49 10.4 0.1 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 ACL95135.1 - 0.12 13.0 0.0 0.23 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 ACL95135.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 ACL95135.1 - 0.2 11.5 0.0 0.56 10.1 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Rad17 PF03215.15 ACL95135.1 - 0.22 11.4 0.0 0.55 10.1 0.0 1.6 2 0 0 2 2 2 0 Rad17 P-loop domain G-alpha PF00503.20 ACL95135.1 - 0.27 10.4 0.0 0.3 10.2 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit PilZ PF07238.14 ACL95136.1 - 1.2e-06 28.8 0.0 1.5e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 PilZ domain Transglut_core PF01841.19 ACL95137.1 - 5.3e-25 88.1 0.0 9.8e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily Bact_transglu_N PF08379.10 ACL95137.1 - 3.5e-24 85.5 0.7 6.2e-24 84.7 0.7 1.4 1 0 0 1 1 1 1 Bacterial transglutaminase-like N-terminal region Alpha-E PF04168.12 ACL95138.1 - 5e-85 285.8 3.1 5.6e-85 285.7 3.1 1.0 1 0 0 1 1 1 1 A predicted alpha-helical domain with a conserved ER motif. CP_ATPgrasp_2 PF14403.6 ACL95139.2 - 1.7e-163 543.9 0.0 2.1e-163 543.6 0.0 1.1 1 0 0 1 1 1 1 Circularly permuted ATP-grasp type 2 CP_ATPgrasp_1 PF04174.13 ACL95139.2 - 1.9e-149 497.2 0.2 2.8e-149 496.6 0.2 1.3 1 0 0 1 1 1 1 A circularly permuted ATPgrasp ATPgrasp_YheCD PF14398.6 ACL95139.2 - 0.074 12.3 0.0 2.5 7.3 0.0 2.2 1 1 0 1 1 1 0 YheC/D like ATP-grasp Biotin_carb_C PF02785.19 ACL95139.2 - 0.12 12.4 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain Bac_surface_Ag PF01103.23 ACL95140.1 - 4.1e-57 194.1 1.7 5.5e-57 193.7 1.7 1.1 1 0 0 1 1 1 1 Surface antigen POTRA_TamA_1 PF17243.2 ACL95140.1 - 2.9e-11 43.3 0.1 6.4e-11 42.2 0.1 1.6 1 0 0 1 1 1 1 POTRA domain TamA domain 1 POTRA PF07244.15 ACL95140.1 - 0.0095 16.5 0.0 3.9 8.1 0.0 3.4 3 0 0 3 3 3 1 Surface antigen variable number repeat TamB PF04357.13 ACL95141.2 - 1.8e-41 142.6 1.9 1.8e-41 142.6 1.9 3.9 4 1 0 4 4 4 1 TamB, inner membrane protein subunit of TAM complex Peptidase_M20 PF01546.28 ACL95142.1 - 8.2e-21 74.6 0.7 1.2e-20 74.2 0.7 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ACL95142.1 - 2e-18 66.3 0.8 5.9e-18 64.8 0.3 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 ACL95142.1 - 0.0029 17.3 0.0 0.0047 16.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 DUF1327 PF07041.11 ACL95142.1 - 0.11 12.5 0.0 0.66 10.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1327) AstA PF04958.12 ACL95143.1 - 2e-123 411.3 0.0 2.2e-123 411.1 0.0 1.0 1 0 0 1 1 1 1 Arginine N-succinyltransferase beta subunit Aldedh PF00171.22 ACL95144.1 - 1.3e-106 356.9 0.0 1.6e-106 356.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PQQ PF01011.21 ACL95144.1 - 0.14 12.1 1.2 35 4.6 0.0 3.8 4 0 0 4 4 4 0 PQQ enzyme repeat PQQ_2 PF13360.6 ACL95144.1 - 0.15 11.6 3.2 0.6 9.6 2.5 2.3 2 1 0 2 2 2 0 PQQ-like domain AstB PF04996.12 ACL95145.1 - 1.9e-190 633.3 0.0 2.1e-190 633.1 0.0 1.0 1 0 0 1 1 1 1 Succinylarginine dihydrolase GGDEF_2 PF17853.1 ACL95145.1 - 0.05 13.9 0.6 0.28 11.4 0.1 2.7 2 1 0 2 2 2 0 GGDEF-like domain Acetyltransf_1 PF00583.25 ACL95146.1 - 2.2e-15 56.9 0.1 2.7e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ACL95146.1 - 1.9e-12 47.4 0.0 3e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ACL95146.1 - 1.8e-11 44.0 0.0 2.4e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ACL95146.1 - 4.4e-08 33.9 0.0 5.4e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ACL95146.1 - 1.1e-07 31.7 0.0 1.8e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 ACL95146.1 - 6e-05 23.1 0.0 0.00015 21.9 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 ACL95146.1 - 0.00078 19.2 0.1 0.00094 18.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ACL95146.1 - 0.013 15.6 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase LytTR PF04397.15 ACL95147.2 - 4e-17 62.3 0.0 6.2e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 LytTr DNA-binding domain Acyl_transf_3 PF01757.22 ACL95148.2 - 2e-23 83.0 21.8 2.4e-23 82.7 21.8 1.1 1 0 0 1 1 1 1 Acyltransferase family Biopterin_H PF00351.21 ACL95149.1 - 6e-45 153.7 0.0 8e-45 153.3 0.0 1.0 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase YccV-like PF08755.11 ACL95150.1 - 7.2e-29 100.2 0.0 8e-29 100.0 0.0 1.0 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Ppx-GppA PF02541.16 ACL95151.2 - 8.5e-50 169.8 0.0 1e-49 169.5 0.0 1.1 1 0 0 1 1 1 1 Ppx/GppA phosphatase family FtsJ PF01728.19 ACL95152.1 - 2.1e-50 171.3 0.0 2.5e-50 171.0 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 ACL95152.1 - 0.00032 20.6 0.0 0.00049 20.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ACL95152.1 - 0.048 13.4 0.0 2.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltrans_Mon PF14314.6 ACL95152.1 - 0.13 10.3 0.0 0.15 10.1 0.0 1.1 1 0 0 1 1 1 0 Virus-capping methyltransferase TrkA_N PF02254.18 ACL95153.1 - 1.9e-34 118.4 0.2 3.8e-34 117.4 0.2 1.5 1 0 0 1 1 1 1 TrkA-N domain Ion_trans_2 PF07885.16 ACL95153.1 - 2.5e-13 49.8 8.3 4.5e-13 49.0 8.3 1.4 1 0 0 1 1 1 1 Ion channel ApbA PF02558.16 ACL95153.1 - 4.1e-05 23.3 0.0 7e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 ACL95153.1 - 4.4e-05 24.0 0.1 0.00017 22.1 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.27 ACL95153.1 - 0.0012 19.3 0.2 0.01 16.4 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 ACL95153.1 - 0.0016 18.7 0.1 0.0028 17.9 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 ACL95153.1 - 0.0017 17.7 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ACL95153.1 - 0.0052 16.1 0.1 0.0081 15.4 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 ACL95153.1 - 0.0052 17.2 0.1 0.015 15.7 0.1 1.8 1 1 0 1 1 1 1 Putative NAD(P)-binding TrkA_C PF02080.21 ACL95153.1 - 0.0061 16.4 0.2 0.014 15.2 0.2 1.5 1 0 0 1 1 1 1 TrkA-C domain NAD_binding_2 PF03446.15 ACL95153.1 - 0.0093 16.2 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 ACL95153.1 - 0.0096 15.3 0.8 0.063 12.6 0.0 2.5 2 1 1 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ni_hydr_CYTB PF01292.20 ACL95153.1 - 0.051 13.2 0.3 0.088 12.4 0.3 1.3 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 UDPG_MGDP_dh_N PF03721.14 ACL95153.1 - 0.051 13.1 0.0 0.095 12.3 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Urocanase PF01175.18 ACL95153.1 - 0.064 12.9 0.0 0.098 12.3 0.0 1.2 1 0 0 1 1 1 0 Urocanase Rossmann-like domain Gp_dh_N PF00044.24 ACL95153.1 - 0.079 13.3 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain adh_short PF00106.25 ACL95153.1 - 0.096 12.1 0.5 0.22 11.0 0.1 1.7 2 0 0 2 2 2 0 short chain dehydrogenase ADH_zinc_N PF00107.26 ACL95153.1 - 0.12 12.4 1.5 0.25 11.3 0.1 2.4 2 1 0 2 2 2 0 Zinc-binding dehydrogenase Ion_trans PF00520.31 ACL95153.1 - 0.37 10.0 1.5 0.74 9.0 1.5 1.4 1 0 0 1 1 1 0 Ion transport protein Peptidase_A24 PF01478.18 ACL95153.1 - 6.5 7.2 8.0 1e+02 3.4 9.4 2.1 1 1 1 2 2 2 0 Type IV leader peptidase family IMPDH PF00478.25 ACL95154.1 - 3.1e-159 529.6 6.8 3.6e-159 529.4 6.8 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 ACL95154.1 - 3.1e-18 66.0 1.4 5.8e-09 36.3 0.1 2.9 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 ACL95154.1 - 1.8e-14 53.9 12.7 2.7e-08 33.6 11.2 2.4 2 1 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 ACL95154.1 - 1.9e-06 27.2 8.6 1.9e-06 27.2 8.6 2.4 3 1 1 4 4 4 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 ACL95154.1 - 0.00069 19.1 7.9 0.033 13.6 0.2 2.9 3 1 1 4 4 4 2 Histidine biosynthesis protein Glu_synthase PF01645.17 ACL95154.1 - 0.0096 15.1 6.7 0.017 14.2 6.7 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase B12-binding PF02310.19 ACL95154.1 - 0.011 15.8 0.9 0.011 15.8 0.9 2.3 3 0 0 3 3 3 0 B12 binding domain QRPTase_C PF01729.19 ACL95154.1 - 0.022 14.6 0.1 0.071 12.9 0.1 1.8 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain NanE PF04131.14 ACL95154.1 - 0.032 13.4 3.7 0.61 9.3 3.5 2.6 1 1 1 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase DHO_dh PF01180.21 ACL95154.1 - 0.12 11.6 5.0 0.062 12.5 0.9 2.2 1 1 1 2 2 2 0 Dihydroorotate dehydrogenase G3P_antiterm PF04309.12 ACL95154.1 - 0.31 10.5 2.3 5.1 6.5 0.2 2.5 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Dus PF01207.17 ACL95154.1 - 0.32 10.1 4.1 7.5 5.5 2.0 2.9 2 1 1 3 3 3 0 Dihydrouridine synthase (Dus) DeoC PF01791.9 ACL95154.1 - 1.2 8.7 10.9 0.71 9.4 5.9 2.6 2 1 1 3 3 3 0 DeoC/LacD family aldolase MAPEG PF01124.18 ACL95155.1 - 9.8e-17 61.1 10.2 1.1e-16 60.9 10.2 1.0 1 0 0 1 1 1 1 MAPEG family Methyltr_RsmB-F PF01189.17 ACL95156.1 - 1.3e-41 142.4 0.0 1.9e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 ACL95156.1 - 1.8e-06 27.8 0.0 2.8e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ACL95156.1 - 0.00018 22.1 0.1 0.0031 18.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 ACL95156.1 - 0.0011 18.3 0.0 0.0038 16.6 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltr_RsmF_N PF17125.5 ACL95156.1 - 0.0012 19.3 0.0 0.0026 18.2 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF Methyltransf_24 PF13578.6 ACL95156.1 - 0.0013 19.7 0.1 0.01 16.9 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.10 ACL95156.1 - 0.0092 15.6 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 ACL95156.1 - 0.13 11.8 0.1 0.98 8.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain GMP_synt_C PF00958.22 ACL95157.1 - 9.5e-45 150.6 0.0 3.2e-44 148.9 0.0 1.9 2 0 0 2 2 2 1 GMP synthase C terminal domain GATase PF00117.28 ACL95157.1 - 1.4e-35 122.8 0.0 2e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 ACL95157.1 - 2.3e-07 30.2 0.1 3.3e-06 26.4 0.1 2.1 2 0 0 2 2 2 1 NAD synthase tRNA_Me_trans PF03054.16 ACL95157.1 - 1.4e-05 24.1 0.1 3.3e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 tRNA methyl transferase Peptidase_C26 PF07722.13 ACL95157.1 - 0.0002 21.2 0.0 0.0012 18.7 0.0 2.2 1 1 0 1 1 1 1 Peptidase C26 ThiI PF02568.14 ACL95157.1 - 0.0092 15.6 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.19 ACL95157.1 - 0.024 14.7 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family QueC PF06508.13 ACL95157.1 - 0.03 13.8 0.0 0.55 9.7 0.0 2.2 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 ACL95157.1 - 0.053 13.2 0.0 0.073 12.7 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase LysR_substrate PF03466.20 ACL95158.1 - 1e-43 149.2 6.4 1.6e-43 148.6 3.3 2.0 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 ACL95158.1 - 6.1e-18 64.5 0.8 1.1e-17 63.7 0.8 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_Crp_2 PF13545.6 ACL95158.1 - 0.023 14.7 0.6 1 9.4 0.1 2.6 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain MarR PF01047.22 ACL95158.1 - 0.084 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_28 PF13518.6 ACL95158.1 - 0.14 12.3 0.0 0.36 11.0 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_IclR PF09339.10 ACL95158.1 - 0.16 11.8 1.0 0.38 10.6 1.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain PepX_C PF08530.10 ACL95159.1 - 1.8e-72 243.9 0.0 3.4e-72 243.1 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 ACL95159.1 - 1.1e-63 215.4 0.6 1.4e-63 215.1 0.6 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 ACL95159.1 - 0.058 12.7 0.1 0.099 11.9 0.1 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 TonB_dep_Rec PF00593.24 ACL95160.1 - 7.3e-46 158.0 25.6 7.3e-46 158.0 25.6 2.2 1 1 0 2 2 2 1 TonB dependent receptor Plug PF07715.15 ACL95160.1 - 1.1e-22 80.6 2.7 1.1e-22 80.6 2.7 2.9 4 0 0 4 4 4 1 TonB-dependent Receptor Plug Domain ABG_transport PF03806.13 ACL95161.1 - 1.2e-218 726.4 24.2 1.4e-218 726.2 24.2 1.0 1 0 0 1 1 1 1 AbgT putative transporter family DcuC PF03606.15 ACL95161.1 - 5.9e-08 31.6 17.3 5.9e-08 31.6 17.3 1.6 2 0 0 2 2 2 1 C4-dicarboxylate anaerobic carrier SCFA_trans PF02667.14 ACL95161.1 - 0.00018 20.6 10.9 0.00018 20.6 10.9 1.8 2 0 0 2 2 2 1 Short chain fatty acid transporter PGA_cap PF09587.10 ACL95162.1 - 6.7e-57 192.9 0.0 8.2e-57 192.6 0.0 1.1 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap DUF1080 PF06439.11 ACL95163.2 - 7.7e-44 150.0 0.0 9.1e-44 149.8 0.0 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1080) Peripla_BP_3 PF13377.6 ACL95164.1 - 7.5e-40 137.0 0.3 2e-39 135.6 0.2 1.7 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 ACL95164.1 - 6.5e-24 84.8 0.0 8.7e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 ACL95164.1 - 4.8e-18 64.7 0.1 1e-17 63.6 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 ACL95164.1 - 1.1e-12 48.1 0.0 9.2e-12 45.1 0.0 2.0 1 1 0 1 1 1 1 Periplasmic binding protein domain HTH_Tnp_ISL3 PF13542.6 ACL95164.1 - 0.00094 18.5 0.4 0.0021 17.4 0.4 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 TetR_N PF00440.23 ACL95164.1 - 0.0068 16.2 0.2 0.02 14.7 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_23 PF13384.6 ACL95164.1 - 0.081 12.7 0.0 0.32 10.9 0.0 2.0 1 0 0 1 1 1 0 Homeodomain-like domain AIRS PF00586.24 ACL95164.1 - 0.13 12.9 0.2 1.3 9.8 0.0 2.7 2 2 0 2 2 2 0 AIR synthase related protein, N-terminal domain HTH_3 PF01381.22 ACL95164.1 - 0.13 12.3 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix HTH_AraC PF00165.23 ACL95164.1 - 0.13 12.4 0.1 0.36 11.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family Nuc_H_symport PF03825.16 ACL95165.1 - 3.1e-173 576.3 33.7 3.5e-173 576.2 33.7 1.0 1 0 0 1 1 1 1 Nucleoside H+ symporter MFS_1_like PF12832.7 ACL95165.1 - 1.9e-26 92.8 19.6 1.9e-26 92.8 19.6 2.7 1 1 2 3 3 3 2 MFS_1 like family MFS_1 PF07690.16 ACL95165.1 - 7e-25 87.7 60.9 8.9e-20 70.9 45.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily EAV_GS PF01309.18 ACL95165.1 - 0.12 12.0 0.9 0.24 11.0 0.9 1.5 1 0 0 1 1 1 0 Equine arteritis virus small envelope glycoprotein AP_endonuc_2 PF01261.24 ACL95166.1 - 6.5e-13 48.6 0.0 1.4e-12 47.6 0.0 1.5 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel UCR_Fe-S_N PF10399.9 ACL95166.1 - 0.053 12.9 1.6 0.12 11.8 1.6 1.5 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal GFO_IDH_MocA PF01408.22 ACL95167.1 - 9.1e-21 74.9 0.1 1.4e-20 74.3 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ACL95167.1 - 3.6e-08 33.4 0.0 1e-07 31.9 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain AP_endonuc_2 PF01261.24 ACL95168.1 - 1.9e-40 138.6 0.1 2.6e-40 138.1 0.1 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel AP_endonuc_2_N PF07582.12 ACL95168.1 - 7.8e-24 83.2 0.2 1.9e-23 81.9 0.2 1.7 1 0 0 1 1 1 1 AP endonuclease family 2 C terminus Cytochrom_C PF00034.21 ACL95169.1 - 1.6e-11 45.2 0.0 1.9e-11 44.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 ACL95169.1 - 8.3e-07 29.2 0.9 6.4e-06 26.4 0.9 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III ACC_epsilon PF13822.6 ACL95169.1 - 0.061 14.0 3.9 4 8.2 0.1 2.3 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit Cytochrom_C550 PF14495.6 ACL95169.1 - 0.18 11.5 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c-550 domain DUF1080 PF06439.11 ACL95170.1 - 3.6e-33 115.2 0.0 4.2e-33 115.0 0.0 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1080) GMC_oxred_C PF05199.13 ACL95171.1 - 2.9e-22 79.8 3.6 1.2e-21 77.7 3.6 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 ACL95171.1 - 1.9e-12 47.2 0.0 6e-10 39.0 0.0 3.0 1 1 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 ACL95171.1 - 1.7e-07 31.1 0.4 4.4e-06 26.5 0.2 2.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ACL95171.1 - 1.1e-06 28.0 0.1 0.00022 20.4 0.0 2.8 2 1 1 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 ACL95171.1 - 5e-05 23.4 1.3 0.00034 20.8 0.1 2.8 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ACL95171.1 - 0.00082 18.7 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ACL95171.1 - 0.0037 16.6 0.4 0.0071 15.6 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 ACL95171.1 - 0.006 17.1 0.0 0.016 15.8 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ACL95171.1 - 0.012 14.9 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ACL95171.1 - 0.019 14.2 0.0 0.041 13.1 0.0 1.5 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 ACL95171.1 - 0.099 11.3 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein GDI PF00996.18 ACL95171.1 - 0.14 10.6 0.0 0.24 9.9 0.0 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor Gluconate_2-dh3 PF13618.6 ACL95172.1 - 5.3e-29 101.2 0.0 6.9e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Gluconate 2-dehydrogenase subunit 3 TAT_signal PF10518.9 ACL95172.1 - 3 7.8 15.2 95 3.1 15.2 2.5 1 1 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence DUF2147 PF09917.9 ACL95173.1 - 1.6e-21 77.0 0.0 2.1e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2147) GMC_oxred_C PF05199.13 ACL95175.1 - 1.9e-23 83.6 0.0 4.3e-23 82.4 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ACL95175.1 - 1.3e-09 37.7 0.6 9.1e-05 21.7 0.4 2.4 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 ACL95175.1 - 5.7e-08 32.3 0.0 3.6e-07 29.7 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 ACL95175.1 - 7.9e-08 32.0 0.0 0.00088 18.7 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase DAO PF01266.24 ACL95175.1 - 2.4e-07 30.7 3.0 1.2e-06 28.4 1.5 2.5 1 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ACL95175.1 - 0.0001 21.5 0.2 0.0002 20.6 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 ACL95175.1 - 0.0012 18.1 0.1 0.0021 17.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 ACL95175.1 - 0.0084 15.4 2.1 1.4 8.1 2.6 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ACL95175.1 - 0.013 16.1 0.1 0.31 11.6 0.3 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ACL95175.1 - 0.016 15.4 1.0 0.016 15.4 1.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 ACL95175.1 - 0.043 13.2 1.6 3.9 6.7 0.0 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 ACL95175.1 - 0.063 12.0 1.0 0.38 9.4 0.8 2.0 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 ACL95175.1 - 0.08 12.0 0.1 1.4 7.9 0.2 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 ACL95175.1 - 0.12 11.6 0.5 0.2 10.9 0.5 1.3 1 0 0 1 1 1 0 FAD binding domain Peptidase_M56 PF05569.11 ACL95176.1 - 1.6e-81 273.8 0.0 2e-81 273.5 0.0 1.1 1 0 0 1 1 1 1 BlaR1 peptidase M56 Ank_2 PF12796.7 ACL95176.1 - 1.1e-22 80.4 0.0 7.1e-11 42.6 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ACL95176.1 - 5e-15 55.4 1.0 0.00046 20.4 0.2 5.1 1 1 4 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ACL95176.1 - 3e-14 51.7 0.0 0.0043 17.4 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 ACL95176.1 - 1.3e-13 51.2 0.0 0.00019 21.9 0.0 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 ACL95176.1 - 6.4e-12 45.4 0.4 0.012 16.0 0.1 5.6 5 0 0 5 5 5 4 Ankyrin repeat UBA PF00627.31 ACL95176.1 - 0.32 11.0 2.8 2.2 8.3 0.1 3.2 3 0 0 3 3 3 0 UBA/TS-N domain Penicillinase_R PF03965.16 ACL95177.1 - 1.5e-36 125.2 0.0 1.7e-36 125.1 0.0 1.0 1 0 0 1 1 1 1 Penicillinase repressor PaaX PF07848.12 ACL95177.1 - 0.00022 21.4 0.0 0.00045 20.4 0.0 1.5 1 0 0 1 1 1 1 PaaX-like protein TrmB PF01978.19 ACL95177.1 - 0.0093 15.8 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB SLT_L PF14718.6 ACL95177.1 - 0.096 12.8 0.2 0.23 11.6 0.0 1.7 2 0 0 2 2 2 0 Soluble lytic murein transglycosylase L domain DED PF01335.21 ACL95177.1 - 0.11 12.8 0.1 0.64 10.4 0.1 2.3 1 1 0 1 1 1 0 Death effector domain LigT_PEase PF02834.16 ACL95178.1 - 9.7e-18 64.2 0.1 1.3e-07 31.7 0.0 2.8 2 1 0 2 2 2 2 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.6 ACL95178.1 - 4.5e-09 36.4 0.0 7e-09 35.8 0.0 1.3 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily ArsC PF03960.15 ACL95179.2 - 4.3e-18 65.1 0.0 4.7e-18 65.0 0.0 1.0 1 0 0 1 1 1 1 ArsC family HAD_2 PF13419.6 ACL95180.2 - 3.9e-27 95.5 0.0 6.7e-27 94.7 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 ACL95180.2 - 7.7e-13 49.3 0.2 1.3e-12 48.5 0.2 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ACL95180.2 - 2.1e-11 44.5 0.2 9.9e-09 35.8 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ACL95180.2 - 1.5e-05 24.9 0.0 3.2e-05 23.9 0.0 1.7 2 1 0 2 2 2 1 HAD-hyrolase-like Acid_PPase PF12689.7 ACL95180.2 - 0.00051 19.9 0.1 0.11 12.3 0.1 2.9 1 1 0 2 2 2 1 Acid Phosphatase Hydrolase_3 PF08282.12 ACL95180.2 - 0.0025 17.6 0.0 5 6.8 0.0 3.1 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 ACL95180.2 - 0.0033 17.5 0.1 0.023 14.8 0.1 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 ACL95180.2 - 0.057 12.8 0.2 1.7 8.0 0.0 2.6 1 1 1 2 2 2 0 Putative Phosphatase Trehalose_PPase PF02358.16 ACL95180.2 - 0.11 11.6 0.0 0.39 9.8 0.0 1.8 2 0 0 2 2 2 0 Trehalose-phosphatase ThrE PF06738.12 ACL95182.1 - 0.024 14.0 1.7 0.026 13.9 0.5 1.6 2 0 0 2 2 2 0 Putative threonine/serine exporter SLATT_1 PF18181.1 ACL95182.1 - 0.12 12.3 0.4 0.97 9.4 0.1 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Sigma70_r4_2 PF08281.12 ACL95183.1 - 3.4e-16 58.7 0.0 5.4e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 ACL95183.1 - 4.7e-12 45.2 0.0 8.3e-12 44.4 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 ACL95183.1 - 6.4e-11 41.9 1.1 1.2e-10 41.0 1.1 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 DUF742 PF05331.11 ACL95183.1 - 0.0051 16.6 0.1 0.0085 15.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF742) HTH_23 PF13384.6 ACL95183.1 - 0.034 14.0 0.0 0.081 12.8 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_24 PF13412.6 ACL95183.1 - 0.079 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma70_r2 PF04542.14 ACL95186.1 - 5.8e-14 51.6 0.5 8.9e-14 51.0 0.5 1.3 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 ACL95186.1 - 3.1e-13 49.0 0.0 7.1e-13 47.9 0.0 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 ACL95186.1 - 7.4e-13 48.0 0.0 1.4e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 GerE PF00196.19 ACL95186.1 - 0.009 15.5 0.0 0.022 14.3 0.0 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family HTH_24 PF13412.6 ACL95186.1 - 0.036 13.6 0.1 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Pantoate_transf PF02548.15 ACL95188.1 - 1.6e-101 339.1 2.0 1.8e-101 338.9 2.0 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PucR PF07905.11 ACL95188.1 - 0.11 12.8 0.4 1.8 8.8 0.0 2.4 2 1 1 3 3 3 0 Purine catabolism regulatory protein-like family TPR_21 PF09976.9 ACL95189.1 - 7e-12 45.5 14.0 7.9e-12 45.3 4.6 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat-like domain TPR_2 PF07719.17 ACL95189.1 - 2.6e-06 27.1 2.3 0.067 13.3 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 ACL95189.1 - 6.5e-05 22.6 0.0 0.057 13.3 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 ACL95189.1 - 0.012 15.8 1.3 6.5 7.1 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat PAP_PilO PF06864.12 ACL95189.1 - 0.019 13.8 6.2 0.086 11.6 1.5 2.3 2 1 0 2 2 2 0 Pilin accessory protein (PilO) TPR_8 PF13181.6 ACL95189.1 - 0.029 14.6 0.0 13 6.3 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat HrpF PF06266.12 ACL95189.1 - 0.052 13.8 0.3 0.052 13.8 0.3 2.0 3 0 0 3 3 3 0 HrpF protein TPR_14 PF13428.6 ACL95189.1 - 0.081 13.8 11.0 6.3 7.9 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 ACL95189.1 - 0.52 11.1 10.2 3.1 8.6 0.1 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat PQQ_2 PF13360.6 ACL95190.1 - 3.5e-77 259.2 11.1 8.1e-68 228.5 5.8 3.1 2 1 1 3 3 3 3 PQQ-like domain PQQ_3 PF13570.6 ACL95190.1 - 1.1e-25 89.4 16.7 0.00055 20.3 0.1 9.1 8 1 0 8 8 8 7 PQQ-like domain PQQ PF01011.21 ACL95190.1 - 1.8e-14 52.8 5.1 0.036 14.0 0.0 7.5 6 1 1 7 7 7 6 PQQ enzyme repeat PUA_3 PF17785.1 ACL95190.1 - 0.14 12.0 0.1 0.97 9.3 0.0 2.5 2 0 0 2 2 2 0 PUA-like domain MMR_HSR1 PF01926.23 ACL95191.1 - 1e-51 173.8 0.0 1.1e-26 93.1 0.0 2.5 3 0 0 3 3 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.6 ACL95191.1 - 2.5e-30 104.6 0.1 4.1e-30 103.9 0.1 1.4 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.18 ACL95191.1 - 5e-25 87.8 0.0 5.4e-12 45.5 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 ACL95191.1 - 1.1e-18 67.5 0.0 2.6e-09 36.9 0.0 5.3 3 2 0 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 ACL95191.1 - 5.7e-18 65.5 0.1 0.00022 21.3 0.0 4.9 4 1 1 5 5 5 4 Dynamin family AIG1 PF04548.16 ACL95191.1 - 1.1e-14 54.3 0.0 7.1e-09 35.3 0.0 2.2 2 0 0 2 2 2 2 AIG1 family Roc PF08477.13 ACL95191.1 - 1.4e-08 35.0 0.0 0.00078 19.7 0.0 3.1 2 2 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 ACL95191.1 - 2.7e-08 33.9 0.0 0.34 10.8 0.0 3.5 3 0 0 3 3 3 3 RsgA GTPase Ras PF00071.22 ACL95191.1 - 4.1e-08 33.0 0.0 0.0019 17.8 0.0 2.4 2 0 0 2 2 2 2 Ras family ABC_tran PF00005.27 ACL95191.1 - 6.8e-07 29.9 0.0 0.02 15.4 0.0 3.4 4 0 0 4 4 3 2 ABC transporter AAA_24 PF13479.6 ACL95191.1 - 1.1e-06 28.5 0.0 0.027 14.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain SRPRB PF09439.10 ACL95191.1 - 3e-06 26.8 0.0 0.042 13.3 0.0 2.2 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit Arf PF00025.21 ACL95191.1 - 2.4e-05 23.8 0.2 0.01 15.3 0.0 3.1 2 2 1 3 3 3 1 ADP-ribosylation factor family MeaB PF03308.16 ACL95191.1 - 0.00032 19.8 0.1 2.2 7.2 0.0 3.6 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB PduV-EutP PF10662.9 ACL95191.1 - 0.00068 19.4 0.0 5.5 6.7 0.0 3.8 3 1 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 ACL95191.1 - 0.00082 19.9 0.0 2.7 8.6 0.0 3.0 2 1 1 3 3 3 2 AAA domain AAA_22 PF13401.6 ACL95191.1 - 0.0015 18.8 0.0 3.7 7.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain TniB PF05621.11 ACL95191.1 - 0.0016 17.9 0.0 1.9 7.8 0.0 2.6 2 0 0 2 2 2 2 Bacterial TniB protein cobW PF02492.19 ACL95191.1 - 0.0023 17.6 0.4 0.9 9.1 0.1 3.3 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 ACL95191.1 - 0.0026 18.0 6.0 0.42 10.8 0.2 3.4 3 2 1 4 4 3 2 AAA domain Septin PF00735.18 ACL95191.1 - 0.0071 15.7 0.0 0.92 8.7 0.0 2.6 2 1 0 2 2 2 1 Septin AAA_29 PF13555.6 ACL95191.1 - 0.008 15.9 0.0 3.8 7.3 0.0 3.1 3 0 0 3 3 3 1 P-loop containing region of AAA domain ATPase_2 PF01637.18 ACL95191.1 - 0.0092 15.9 0.0 0.19 11.6 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Gtr1_RagA PF04670.12 ACL95191.1 - 0.01 15.2 0.0 0.37 10.1 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region NTPase_1 PF03266.15 ACL95191.1 - 0.012 15.5 0.0 6.2 6.7 0.0 2.7 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.22 ACL95191.1 - 0.015 15.7 0.0 6.3 7.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 ACL95191.1 - 0.019 15.1 1.3 4.4 7.5 0.1 3.1 3 1 0 3 3 3 0 AAA domain AAA_16 PF13191.6 ACL95191.1 - 0.067 13.6 1.5 9.1 6.6 0.1 2.9 2 1 0 2 2 2 0 AAA ATPase domain Nuc_deoxyri_tr2 PF15891.5 ACL95191.1 - 0.078 13.3 0.4 0.85 10.0 0.1 2.6 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase like NB-ARC PF00931.22 ACL95191.1 - 0.15 11.2 0.0 13 4.9 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain DUF2514 PF10721.9 ACL95191.1 - 0.84 9.7 7.4 2.4 8.2 7.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) MCPsignal PF00015.21 ACL95192.2 - 5.2e-54 182.6 20.9 5.2e-54 182.6 20.9 3.0 2 1 0 3 3 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain PAS_3 PF08447.12 ACL95192.2 - 4.5e-13 49.3 0.1 1.4e-12 47.7 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 ACL95192.2 - 5.7e-13 49.1 0.0 2.4e-12 47.1 0.0 2.1 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 ACL95192.2 - 4.5e-10 39.7 0.0 1.1e-09 38.5 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 ACL95192.2 - 1.6e-06 28.1 0.0 7.7e-06 25.9 0.0 2.2 2 0 0 2 2 2 1 PAS fold BLOC1_2 PF10046.9 ACL95192.2 - 0.0057 16.9 14.3 0.74 10.2 0.1 4.8 3 2 2 5 5 5 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 GldM_N PF12081.8 ACL95192.2 - 0.045 13.8 5.5 0.36 10.9 0.3 2.8 3 0 0 3 3 3 0 GldM N-terminal domain Syntaxin_2 PF14523.6 ACL95192.2 - 0.059 13.7 10.2 3.2 8.2 2.0 3.9 2 1 2 4 4 4 0 Syntaxin-like protein Allexi_40kDa PF05549.11 ACL95192.2 - 0.11 11.9 1.4 4.8 6.6 0.0 2.4 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF1664 PF07889.12 ACL95192.2 - 0.12 12.4 12.9 0.7 9.9 2.5 3.7 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) HAMP PF00672.25 ACL95192.2 - 0.14 12.6 3.0 1 9.8 0.1 3.8 3 1 0 3 3 2 0 HAMP domain DUF948 PF06103.11 ACL95192.2 - 0.17 12.2 16.3 3.1 8.1 0.8 4.3 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) SHE3 PF17078.5 ACL95192.2 - 0.17 11.6 1.2 1.7 8.3 0.1 2.4 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 Tox-URI2 PF15653.6 ACL95192.2 - 0.18 12.1 0.2 0.9 9.8 0.0 2.1 2 0 0 2 2 2 0 URI fold toxin 2 GIT1_C PF12205.8 ACL95192.2 - 0.26 11.4 4.1 12 6.0 0.5 2.9 2 1 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term Synaptobrevin PF00957.21 ACL95192.2 - 0.33 10.8 4.8 0.25 11.2 1.4 2.4 2 0 0 2 2 2 0 Synaptobrevin Laminin_II PF06009.12 ACL95192.2 - 0.46 10.5 19.4 0.71 9.9 3.8 3.3 2 2 1 3 3 3 0 Laminin Domain II GCN5L1 PF06320.13 ACL95192.2 - 0.5 10.5 13.7 15 5.8 0.1 4.0 2 2 2 4 4 4 0 GCN5-like protein 1 (GCN5L1) zf-C4H2 PF10146.9 ACL95192.2 - 0.66 10.2 2.9 0.73 10.1 0.0 2.3 2 1 1 3 3 3 0 Zinc finger-containing protein DASH_Dad1 PF08649.10 ACL95192.2 - 0.8 9.9 3.7 0.55 10.5 0.4 2.5 2 0 0 2 2 2 0 DASH complex subunit Dad1 SKA1 PF07160.12 ACL95192.2 - 1.1 9.1 6.4 1.2 9.0 0.6 2.8 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 AAA_13 PF13166.6 ACL95192.2 - 1.2 7.7 16.2 0.39 9.3 4.7 2.1 2 0 0 2 2 2 0 AAA domain V_ATPase_I PF01496.19 ACL95192.2 - 1.3 6.9 7.5 6.5 4.5 7.5 1.9 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DnaB_bind PF10410.9 ACL95192.2 - 3.2 8.0 5.6 38 4.6 0.2 3.3 3 0 0 3 3 3 0 DnaB-helicase binding domain of primase DUF1720 PF08226.11 ACL95192.2 - 4 7.9 9.4 7.3 7.1 9.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1720) TMPIT PF07851.13 ACL95192.2 - 6.4 5.9 7.0 13 5.0 0.9 2.5 3 0 0 3 3 2 0 TMPIT-like protein adh_short PF00106.25 ACL95193.1 - 1.2e-42 145.6 0.0 1.4e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ACL95193.1 - 1.1e-33 116.7 0.0 1.4e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ACL95193.1 - 4.2e-13 49.6 0.1 5.8e-13 49.2 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ACL95193.1 - 0.00026 20.6 1.0 0.0025 17.3 1.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 ACL95193.1 - 0.003 17.0 0.0 0.0041 16.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) ApbA PF02558.16 ACL95193.1 - 0.015 15.0 0.1 0.024 14.3 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA SMC_hinge PF06470.13 ACL95193.1 - 0.065 13.5 0.1 2.1 8.7 0.1 2.6 2 1 0 2 2 2 0 SMC proteins Flexible Hinge Domain NAD_binding_10 PF13460.6 ACL95193.1 - 0.086 12.7 3.3 0.73 9.7 3.3 2.1 1 1 0 1 1 1 0 NAD(P)H-binding F420_oxidored PF03807.17 ACL95193.1 - 0.1 13.2 0.2 0.26 11.9 0.2 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent LDcluster4 PF18306.1 ACL95193.1 - 0.14 11.7 0.9 0.23 11.0 0.9 1.3 1 0 0 1 1 1 0 SLOG cluster4 family SBF_like PF13593.6 ACL95194.1 - 4.1e-96 322.0 28.2 4.7e-96 321.8 28.2 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 ACL95194.1 - 9.6e-14 51.5 10.3 9.6e-14 51.5 10.3 2.5 2 1 1 3 3 3 1 Sodium Bile acid symporter family RE_EcoO109I PF14511.6 ACL95194.1 - 0.24 11.0 0.1 0.43 10.2 0.1 1.3 1 0 0 1 1 1 0 Type II restriction endonuclease EcoO109I GATase_7 PF13537.6 ACL95195.1 - 1.5e-20 73.3 0.0 2.9e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 ACL95195.1 - 1.2e-19 70.8 0.0 2.4e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 ACL95195.1 - 2.3e-09 37.0 0.1 4.1e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 ACL95195.1 - 0.0013 17.7 0.1 0.0021 17.0 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II PRTase_2 PF15609.6 ACL95195.1 - 0.026 14.0 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase RPN6_N PF18055.1 ACL95195.1 - 0.11 12.9 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN6 N-terminal domain Colicin_V PF02674.16 ACL95196.1 - 1.5e-27 96.3 9.5 1.9e-27 96.0 9.5 1.1 1 0 0 1 1 1 1 Colicin V production protein DctQ PF04290.12 ACL95196.1 - 0.49 10.3 8.9 0.78 9.7 8.9 1.3 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF3382 PF11862.8 ACL95196.1 - 0.55 10.5 8.7 0.93 9.8 5.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3382) DUF2070 PF09843.9 ACL95196.1 - 1.2 7.3 3.9 1.5 7.1 3.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ATPase PF06745.13 ACL95197.1 - 1.9e-16 60.1 0.0 5.9e-11 42.2 0.0 2.1 1 1 1 2 2 2 2 KaiC AAA_25 PF13481.6 ACL95197.1 - 3e-15 56.3 1.9 1.3e-14 54.3 1.9 1.9 1 1 0 1 1 1 1 AAA domain Rubredoxin_2 PF18073.1 ACL95197.1 - 1e-10 41.2 7.6 1.8e-10 40.4 7.6 1.4 1 0 0 1 1 1 1 Rubredoxin metal binding domain ChlI PF13541.6 ACL95197.1 - 1.4e-08 34.6 0.0 4.3e-08 33.0 0.0 1.7 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase DnaB_C PF03796.15 ACL95197.1 - 1.5e-07 31.1 0.0 0.00044 19.7 0.0 2.2 1 1 1 2 2 2 2 DnaB-like helicase C terminal domain Rad51 PF08423.11 ACL95197.1 - 3.4e-06 26.5 0.1 3.8e-05 23.1 0.1 2.0 1 1 0 1 1 1 1 Rad51 RecA PF00154.21 ACL95197.1 - 4.7e-06 26.3 0.3 6.9e-06 25.7 0.3 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_16 PF13191.6 ACL95197.1 - 8.6e-06 26.2 0.1 2.2e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 ACL95197.1 - 8.8e-05 22.9 0.0 0.00016 22.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ACL95197.1 - 0.00029 21.1 0.0 0.00062 20.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 ACL95197.1 - 0.00073 19.3 0.0 0.0017 18.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 ACL95197.1 - 0.0025 17.1 0.0 0.0035 16.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 ACL95197.1 - 0.0031 17.4 0.9 0.0089 15.9 0.0 2.1 2 1 1 3 3 2 1 NTPase DAP3 PF10236.9 ACL95197.1 - 0.0041 16.3 0.0 0.0084 15.3 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 IstB_IS21 PF01695.17 ACL95197.1 - 0.0071 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Lon_C PF05362.13 ACL95197.1 - 0.014 14.9 0.1 0.043 13.3 0.0 1.7 2 0 0 2 2 2 0 Lon protease (S16) C-terminal proteolytic domain AAA_33 PF13671.6 ACL95197.1 - 0.016 15.4 0.0 0.026 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ACL95197.1 - 0.088 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Glyco_hydro_97 PF10566.9 ACL95197.1 - 0.095 12.0 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Glycoside hydrolase 97 AAA_29 PF13555.6 ACL95197.1 - 0.12 12.1 0.2 0.28 11.0 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 ACL95197.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 ACL95197.1 - 0.13 11.3 0.1 0.31 10.1 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain cobW PF02492.19 ACL95197.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain GvpD PF07088.11 ACL95197.1 - 0.17 10.5 0.0 1.8 7.1 0.0 2.0 1 1 1 2 2 2 0 GvpD gas vesicle protein AAA_30 PF13604.6 ACL95197.1 - 0.22 11.2 2.4 0.92 9.2 2.4 1.9 1 1 0 1 1 1 0 AAA domain Ala_racemase_N PF01168.20 ACL95198.1 - 5.5e-57 192.9 0.1 7.7e-57 192.4 0.1 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Ala_racemase_C PF00842.21 ACL95198.1 - 1.4e-36 125.0 0.0 2.1e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, C-terminal domain MarC PF01914.17 ACL95199.1 - 4.5e-43 147.0 2.6 5.2e-43 146.8 2.6 1.0 1 0 0 1 1 1 1 MarC family integral membrane protein Trp_oprn_chp PF09534.10 ACL95199.1 - 0.057 13.2 10.3 0.018 14.8 1.8 2.8 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) 4HBT PF03061.22 ACL95200.1 - 6.8e-12 45.6 0.0 9.1e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 ACL95200.1 - 3.6e-07 30.7 0.1 4.3e-07 30.5 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily TetR_N PF00440.23 ACL95201.1 - 2.4e-14 52.8 0.6 5.4e-14 51.7 0.6 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_7 PF02796.15 ACL95201.1 - 0.025 14.6 0.0 0.056 13.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase eIF-3c_N PF05470.12 ACL95201.1 - 0.048 12.0 0.1 0.059 11.7 0.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus AvrE_T3Es PF11725.8 ACL95201.1 - 0.063 10.5 0.1 0.076 10.2 0.1 1.0 1 0 0 1 1 1 0 AvrE-family Type-III effector proteins (T3Es) AfsA PF03756.13 ACL95201.1 - 0.093 12.7 1.8 0.1 12.6 0.6 1.7 2 1 0 2 2 2 0 A-factor biosynthesis hotdog domain HTH_19 PF12844.7 ACL95201.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain TnsD PF15978.5 ACL95201.1 - 0.21 10.5 0.0 0.24 10.4 0.0 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D HTH_23 PF13384.6 ACL95201.1 - 0.33 10.8 3.3 0.39 10.6 0.0 2.7 2 1 1 3 3 3 0 Homeodomain-like domain DnaB_C PF03796.15 ACL95202.1 - 7.4e-100 333.5 0.0 9.3e-100 333.2 0.0 1.1 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain DnaB PF00772.21 ACL95202.1 - 6e-27 93.7 0.0 1e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase N terminal domain AAA_25 PF13481.6 ACL95202.1 - 3.8e-13 49.5 0.0 6.1e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 ACL95202.1 - 0.024 14.0 0.0 0.055 12.8 0.0 1.6 1 1 0 1 1 1 0 KaiC AAA_16 PF13191.6 ACL95202.1 - 0.036 14.5 0.3 0.24 11.8 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 ACL95202.1 - 0.092 13.2 0.2 0.65 10.4 0.2 2.3 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 ACL95202.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain TonB_dep_Rec PF00593.24 ACL95203.1 - 5.3e-46 158.5 30.2 5.3e-46 158.5 30.2 1.9 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 ACL95203.1 - 2.7e-21 76.2 3.2 4.5e-21 75.4 0.6 2.8 3 0 0 3 3 3 1 TonB-dependent Receptor Plug Domain MtrB_PioB PF11854.8 ACL95203.1 - 0.0015 17.0 5.1 0.027 12.8 0.4 3.2 4 0 0 4 4 4 2 Putative outer membrane beta-barrel porin, MtrB/PioB Ribosomal_L9_C PF03948.14 ACL95204.1 - 1.2e-23 83.4 0.6 2.4e-23 82.4 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, C-terminal domain Ribosomal_L9_N PF01281.19 ACL95204.1 - 7.2e-21 73.5 0.1 7.2e-21 73.5 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L9, N-terminal domain Profilin PF00235.19 ACL95204.1 - 0.082 13.2 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Profilin Ribosomal_S18 PF01084.20 ACL95205.1 - 7e-26 90.2 0.3 8.6e-26 89.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S18 Ribosomal_S6 PF01250.17 ACL95206.1 - 3.4e-29 101.0 0.1 4e-29 100.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 PEP-utilizers PF00391.23 ACL95206.1 - 0.018 14.7 0.0 0.069 12.9 0.0 1.8 2 0 0 2 2 2 0 PEP-utilising enzyme, mobile domain DUF2783 PF10932.8 ACL95206.1 - 0.068 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2783) BRCT_2 PF16589.5 ACL95206.1 - 0.091 13.2 0.0 0.098 13.1 0.0 1.3 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain FA_hydroxylase PF04116.13 ACL95208.1 - 3.4e-27 95.4 12.4 3.4e-27 95.4 12.4 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily HTH_18 PF12833.7 ACL95209.1 - 1.9e-15 56.8 0.1 1.1e-14 54.4 0.1 2.3 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_AraC PF00165.23 ACL95209.1 - 1.5e-07 31.3 0.0 4.1e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family UPF0126 PF03458.13 ACL95209.1 - 9.8 6.2 12.0 0.099 12.5 2.5 2.7 4 0 0 4 4 4 0 UPF0126 domain AhpC-TSA PF00578.21 ACL95210.1 - 1.5e-20 73.3 0.0 1.9e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ACL95210.1 - 3.7e-14 52.7 0.1 4.9e-14 52.3 0.1 1.1 1 0 0 1 1 1 1 Redoxin Acyl_transf_1 PF00698.21 ACL95211.1 - 1.8e-38 132.8 4.1 2.1e-38 132.6 4.1 1.0 1 0 0 1 1 1 1 Acyl transferase domain adh_short_C2 PF13561.6 ACL95212.1 - 4.4e-62 209.7 9.4 5e-62 209.5 9.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ACL95212.1 - 9.9e-58 194.8 4.1 1.2e-57 194.5 4.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ACL95212.1 - 4e-23 82.2 2.7 5.7e-23 81.7 2.7 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ACL95212.1 - 1.9e-08 34.4 3.5 2.3e-08 34.1 3.5 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ACL95212.1 - 3.7e-05 23.3 1.3 9.1e-05 22.0 1.3 1.8 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 ACL95212.1 - 0.00088 19.5 1.0 0.0027 18.0 0.8 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 ACL95212.1 - 0.0018 17.5 0.1 0.0024 17.1 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 ACL95212.1 - 0.0049 16.5 1.9 0.0049 16.5 1.9 1.8 3 0 0 3 3 3 1 NmrA-like family F420_oxidored PF03807.17 ACL95212.1 - 0.0052 17.3 2.0 0.049 14.2 0.7 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent GDP_Man_Dehyd PF16363.5 ACL95212.1 - 0.013 14.9 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 2-Hacid_dh_C PF02826.19 ACL95212.1 - 0.032 13.6 0.9 0.044 13.1 0.2 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 ACL95212.1 - 0.048 12.7 1.6 0.052 12.6 0.7 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain YjeF_N PF03853.15 ACL95212.1 - 0.063 13.2 2.2 0.3 10.9 0.5 2.3 2 1 0 2 2 2 0 YjeF-related protein N-terminus TPP_enzyme_N PF02776.18 ACL95212.1 - 0.075 12.6 3.1 0.15 11.6 0.1 2.5 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain ApbA PF02558.16 ACL95212.1 - 0.099 12.3 0.8 0.18 11.5 0.2 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DFP PF04127.15 ACL95212.1 - 0.099 12.5 5.0 0.78 9.5 2.1 2.3 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Ldh_1_N PF00056.23 ACL95212.1 - 0.16 12.1 4.4 0.078 13.1 1.6 1.9 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 ACL95212.1 - 0.18 11.8 4.4 0.17 11.9 1.9 2.0 2 1 0 2 2 2 0 Zinc-binding dehydrogenase HEM4 PF02602.15 ACL95212.1 - 0.2 11.0 2.7 2.2 7.6 2.5 2.0 1 1 0 1 1 1 0 Uroporphyrinogen-III synthase HemD 3HCDH_N PF02737.18 ACL95212.1 - 0.24 11.3 5.3 0.17 11.8 1.6 2.4 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_23 PF13489.6 ACL95213.1 - 4e-12 46.3 0.0 6.3e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ACL95213.1 - 2e-05 25.3 0.2 5.5e-05 23.8 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ACL95213.1 - 0.00011 22.8 0.1 0.00053 20.6 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ACL95213.1 - 0.0042 16.9 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ACL95213.1 - 0.0054 17.4 0.3 0.024 15.3 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.25 ACL95214.1 - 4.6e-12 46.1 0.3 5.1e-12 46.0 0.3 1.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 ACL95214.1 - 3.6e-05 23.9 1.0 3.7e-05 23.9 1.0 1.1 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.12 ACL95214.1 - 0.035 14.6 0.3 0.039 14.4 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Ribosomal_L50 PF10501.9 ACL95214.1 - 0.051 13.7 0.0 0.06 13.5 0.0 1.4 1 1 0 1 1 1 0 Ribosomal subunit 39S DUF3877 PF12993.7 ACL95214.1 - 0.062 13.2 0.0 0.069 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) ketoacyl-synt PF00109.26 ACL95215.1 - 7.6e-62 209.2 0.6 7.6e-62 209.2 0.6 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 ACL95215.1 - 1.3e-34 118.8 1.0 2.4e-34 117.9 1.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 ACL95215.1 - 2.6e-06 27.0 1.7 1.4e-05 24.6 0.8 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 ACL95215.1 - 0.0022 18.4 0.1 0.0065 16.9 0.1 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension YceG PF02618.16 ACL95216.1 - 6.5e-82 275.2 0.0 7.6e-82 275.0 0.0 1.0 1 0 0 1 1 1 1 YceG-like family YicC_N PF03755.13 ACL95217.1 - 2.3e-30 106.0 0.9 1.2e-29 103.7 0.0 2.1 2 0 0 2 2 2 1 YicC-like family, N-terminal region DUF1732 PF08340.11 ACL95217.1 - 1.9e-29 101.5 0.2 3.5e-29 100.6 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1732) Guanylate_kin PF00625.21 ACL95218.1 - 1.3e-45 155.3 0.0 1.5e-45 155.1 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 ACL95218.1 - 9.8e-05 22.5 0.0 0.00036 20.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ACL95218.1 - 0.0032 17.9 2.3 0.028 14.8 2.3 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ACL95218.1 - 0.0074 16.6 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain MobB PF03205.14 ACL95218.1 - 0.0077 16.1 0.0 0.78 9.6 0.0 2.2 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RsgA_GTPase PF03193.16 ACL95218.1 - 0.013 15.4 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 ACL95218.1 - 0.092 12.8 0.0 0.14 12.2 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 ACL95218.1 - 0.097 12.2 0.2 4.5 6.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 ACL95218.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 ACL95218.1 - 0.15 12.6 0.0 0.28 11.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain Transgly_assoc PF04226.13 ACL95219.1 - 5e-16 58.7 18.3 5.5e-16 58.6 13.0 2.1 2 0 0 2 2 2 1 Transglycosylase associated protein DUF4235 PF14019.6 ACL95219.1 - 0.03 14.4 6.2 2.8 8.1 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF4235) DUF5518 PF17647.1 ACL95219.1 - 0.032 14.4 14.5 0.045 13.9 14.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5518) EMP70 PF02990.16 ACL95219.1 - 0.04 12.6 4.1 0.75 8.4 4.1 2.0 1 1 0 1 1 1 0 Endomembrane protein 70 LptF_LptG PF03739.14 ACL95219.1 - 1.5 7.6 7.0 1.6 7.5 7.0 1.0 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG HWE_HK PF07536.14 ACL95220.2 - 1.7e-23 83.1 0.4 5.1e-23 81.6 0.0 2.1 2 0 0 2 2 2 1 HWE histidine kinase HisKA_2 PF07568.12 ACL95220.2 - 0.00016 21.7 0.0 0.0005 20.1 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase PG_binding_1 PF01471.18 ACL95220.2 - 0.077 13.2 0.1 0.17 12.1 0.1 1.5 1 0 0 1 1 1 0 Putative peptidoglycan binding domain HATPase_c_2 PF13581.6 ACL95220.2 - 0.13 12.2 0.0 0.35 10.8 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain ArAE_2 PF10334.9 ACL95220.2 - 0.15 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Aromatic acid exporter family member 2 RrnaAD PF00398.20 ACL95222.2 - 2.5e-55 187.4 0.0 3.1e-55 187.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 ACL95222.2 - 0.00059 20.5 0.0 0.0012 19.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ACL95222.2 - 0.014 16.0 0.0 0.033 14.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PdxA PF04166.12 ACL95223.1 - 1.5e-98 329.7 0.0 1.8e-98 329.5 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA Rotamase PF00639.21 ACL95224.1 - 8.5e-28 97.2 0.8 2.7e-15 57.1 0.0 3.3 3 0 0 3 3 3 2 PPIC-type PPIASE domain Rotamase_3 PF13616.6 ACL95224.1 - 1.7e-21 76.9 0.0 1.1e-12 48.5 0.0 2.6 2 0 0 2 2 2 2 PPIC-type PPIASE domain SurA_N PF09312.11 ACL95224.1 - 1.4e-14 54.1 5.5 3.1e-14 53.0 5.5 1.6 1 0 0 1 1 1 1 SurA N-terminal domain Rotamase_2 PF13145.6 ACL95224.1 - 6.4e-12 46.4 11.3 6.7e-06 27.0 0.1 3.2 3 1 1 4 4 4 2 PPIC-type PPIASE domain SurA_N_3 PF13624.6 ACL95224.1 - 1.7e-09 37.6 1.7 1.7e-09 37.6 1.7 2.0 2 0 0 2 2 2 1 SurA N-terminal domain SurA_N_2 PF13623.6 ACL95224.1 - 0.026 14.4 8.9 0.03 14.2 5.0 2.7 2 1 1 3 3 3 0 SurA N-terminal domain TusA PF01206.17 ACL95224.1 - 0.18 11.7 0.5 0.68 9.8 0.1 2.1 2 0 0 2 2 2 0 Sulfurtransferase TusA LptD PF04453.14 ACL95225.3 - 4e-72 243.6 0.1 6.8e-72 242.8 0.1 1.3 1 0 0 1 1 1 1 LPS transport system D OstA PF03968.14 ACL95225.3 - 0.00034 20.8 1.4 0.0012 19.0 0.2 2.5 2 1 0 2 2 2 1 OstA-like protein OstA_2 PF13100.6 ACL95225.3 - 0.014 15.0 0.1 0.14 11.8 0.0 2.3 2 0 0 2 2 2 0 OstA-like protein LptC PF06835.13 ACL95225.3 - 0.039 13.5 0.0 6.6 6.3 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide-assembly, LptC-related LptF_LptG PF03739.14 ACL95226.1 - 3.8e-54 183.9 8.1 4.3e-54 183.7 8.1 1.0 1 0 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG LptF_LptG PF03739.14 ACL95227.1 - 1.5e-59 201.6 2.8 1.7e-59 201.5 2.8 1.0 1 0 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG E1-E2_ATPase PF00122.20 ACL95227.1 - 0.084 12.4 3.8 0.22 11.0 3.8 1.7 1 0 0 1 1 1 0 E1-E2 ATPase Peptidase_M17 PF00883.21 ACL95228.1 - 8.6e-122 406.3 0.0 1.2e-121 405.8 0.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 ACL95228.1 - 7.6e-25 87.2 6.5 1.8e-24 86.0 6.5 1.6 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain DNA_pol3_chi PF04364.13 ACL95229.1 - 1.6e-35 122.2 0.0 2e-35 121.9 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase III chi subunit, HolC Inhibitor_I78 PF11720.8 ACL95230.1 - 0.00037 20.5 0.1 0.0014 18.6 0.1 1.9 1 1 0 1 1 1 1 Peptidase inhibitor I78 family DUF3558 PF12079.8 ACL95230.1 - 0.0056 16.7 5.4 0.0067 16.4 5.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3558) potato_inhibit PF00280.18 ACL95230.1 - 0.021 15.5 0.1 0.03 15.0 0.1 1.5 1 1 0 1 1 1 0 Potato inhibitor I family LPAM_1 PF08139.12 ACL95230.1 - 0.048 14.2 1.6 0.077 13.5 1.6 1.3 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site CsgG PF03783.14 ACL95231.2 - 8.6e-54 182.0 0.7 1e-53 181.8 0.7 1.1 1 0 0 1 1 1 1 Curli production assembly/transport component CsgG TolB_N PF04052.13 ACL95231.2 - 6.4e-05 23.1 0.1 0.0096 16.1 0.0 2.3 2 0 0 2 2 2 2 TolB amino-terminal domain LptE PF04390.12 ACL95231.2 - 0.0022 18.6 0.0 0.0044 17.7 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide-assembly Cytochrom_C PF00034.21 ACL95232.2 - 7.8e-07 30.2 1.1 1.4e-05 26.1 1.1 2.1 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 ACL95232.2 - 9.3e-07 29.1 0.1 1.2e-06 28.7 0.1 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Peptidase_C58 PF03543.14 ACL95232.2 - 0.15 11.8 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen ABC_tran PF00005.27 ACL95234.1 - 5.7e-44 150.0 0.0 3.2e-22 79.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 ACL95234.1 - 1.2e-24 86.1 3.0 8.1e-24 83.5 1.5 2.7 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.6 ACL95234.1 - 4.3e-14 53.0 10.6 0.00059 19.7 0.1 4.3 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_CTD PF16326.5 ACL95234.1 - 3.1e-10 40.1 0.7 3.1e-10 40.1 0.7 2.8 3 0 0 3 3 3 1 ABC transporter C-terminal domain SMC_N PF02463.19 ACL95234.1 - 1.2e-08 34.7 1.8 0.0016 18.0 0.9 4.1 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ACL95234.1 - 3.5e-06 27.3 0.0 0.046 14.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 ACL95234.1 - 6.3e-06 25.8 0.1 0.015 15.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 ACL95234.1 - 9.7e-06 26.2 0.1 0.0033 18.0 0.0 3.0 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 ACL95234.1 - 1.4e-05 25.2 0.0 0.016 15.3 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 ACL95234.1 - 5.6e-05 23.7 2.2 0.11 13.0 0.0 3.2 4 0 0 4 4 3 2 AAA domain RsgA_GTPase PF03193.16 ACL95234.1 - 8.7e-05 22.5 0.3 0.1 12.5 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase NACHT PF05729.12 ACL95234.1 - 0.00024 21.1 0.0 0.28 11.1 0.0 2.6 2 0 0 2 2 2 2 NACHT domain MeaB PF03308.16 ACL95234.1 - 0.00058 18.9 0.3 0.2 10.6 0.1 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 ACL95234.1 - 0.00061 20.2 0.5 0.72 10.3 0.2 2.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 ACL95234.1 - 0.0012 18.9 0.3 0.3 11.1 0.1 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE SbcCD_C PF13558.6 ACL95234.1 - 0.0019 18.4 0.9 1.5 9.1 0.2 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 ACL95234.1 - 0.0021 17.3 0.3 1.3 8.1 0.1 2.3 2 0 0 2 2 2 2 NB-ARC domain AAA_24 PF13479.6 ACL95234.1 - 0.0026 17.5 0.1 1.6 8.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ACL95234.1 - 0.0029 17.8 0.7 0.65 10.1 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_15 PF13175.6 ACL95234.1 - 0.0031 17.3 0.2 1.8 8.2 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain DUF87 PF01935.17 ACL95234.1 - 0.0033 17.6 3.7 2.4 8.2 0.0 3.6 4 0 0 4 4 4 1 Helicase HerA, central domain RNA_helicase PF00910.22 ACL95234.1 - 0.0088 16.4 0.0 7 7.1 0.0 2.5 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.15 ACL95234.1 - 0.016 15.1 0.2 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_16 PF13191.6 ACL95234.1 - 0.017 15.5 3.6 6.1 7.2 0.0 3.4 2 1 1 3 3 3 0 AAA ATPase domain AAA_5 PF07728.14 ACL95234.1 - 0.079 13.0 0.9 14 5.7 0.1 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 ACL95234.1 - 0.093 13.1 0.2 0.97 9.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 ACL95234.1 - 0.14 11.3 0.0 1.6 7.8 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit RuvB_N PF05496.12 ACL95234.1 - 0.14 11.9 0.2 2.3 7.9 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_13 PF13166.6 ACL95234.1 - 0.16 10.6 2.4 3.2 6.3 0.0 3.2 4 0 0 4 4 4 0 AAA domain DUF3584 PF12128.8 ACL95234.1 - 4.3 4.7 12.2 4.7 4.6 1.2 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3584) Thymidylate_kin PF02223.17 ACL95234.1 - 5.5 6.6 5.9 4.5 6.9 0.1 3.0 3 0 0 3 3 3 0 Thymidylate kinase NDK PF00334.19 ACL95235.1 - 1.1e-48 164.7 0.0 1.2e-48 164.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DUF1275 PF06912.11 ACL95237.1 - 2.6e-17 63.4 13.3 2.9e-17 63.2 13.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) SecG PF03840.14 ACL95237.1 - 0.24 11.5 5.4 0.31 11.2 0.6 2.2 2 0 0 2 2 2 0 Preprotein translocase SecG subunit SNARE_assoc PF09335.11 ACL95238.1 - 2.7e-16 60.1 6.6 2.7e-16 60.1 6.6 1.7 1 1 1 2 2 2 1 SNARE associated Golgi protein Formyl_trans_N PF00551.19 ACL95239.1 - 8.5e-51 172.3 0.0 9.6e-51 172.1 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase AIRS_C PF02769.22 ACL95240.1 - 1.3e-34 119.6 0.0 2.1e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 ACL95240.1 - 8.9e-15 55.1 1.1 1.6e-14 54.3 1.1 1.4 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain DNA_pol_A_exo1 PF01612.20 ACL95241.1 - 5.6e-35 120.6 0.0 8.2e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 ACL95241.1 - 1.3e-16 60.3 0.5 6.1e-14 51.8 0.0 3.3 3 0 0 3 3 3 2 HRDC domain Response_reg PF00072.24 ACL95242.2 - 5.9e-28 97.3 0.4 1.3e-27 96.2 0.1 1.7 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 ACL95242.2 - 7.9e-28 97.2 0.0 1.3e-27 96.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ACL95242.2 - 1.1e-10 41.3 1.6 8.3e-10 38.6 0.8 2.9 3 1 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 ACL95242.2 - 0.007 16.3 0.2 0.031 14.2 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 ACL95242.2 - 0.043 13.6 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Beta-lactamase PF00144.24 ACL95243.1 - 1.8e-56 191.8 4.5 2.4e-56 191.4 4.5 1.1 1 0 0 1 1 1 1 Beta-lactamase OapA_N PF08525.11 ACL95243.1 - 0.097 12.6 1.7 0.19 11.7 1.7 1.5 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif RE_AccI PF09545.10 ACL95243.1 - 0.3 10.0 0.0 0.43 9.5 0.0 1.1 1 0 0 1 1 1 0 AccI restriction endonuclease HTH_12 PF08461.10 ACL95243.1 - 0.33 10.9 1.0 3.3 7.7 0.0 2.6 3 0 0 3 3 3 0 Ribonuclease R winged-helix domain Ppx-GppA PF02541.16 ACL95245.1 - 3.1e-43 148.3 0.0 4.1e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Cecropin PF00272.19 ACL95246.1 - 0.077 12.7 0.8 6 6.7 0.1 2.4 2 0 0 2 2 2 0 Cecropin family PP_kinase_C_1 PF17941.1 ACL95247.2 - 4.6e-76 254.0 0.0 2.7e-75 251.5 0.0 2.0 2 0 0 2 2 2 1 Polyphosphate kinase C-terminal domain 1 PP_kinase_C PF13090.6 ACL95247.2 - 2e-61 206.5 0.0 9.1e-61 204.3 0.0 2.0 2 0 0 2 2 2 1 Polyphosphate kinase C-terminal domain 2 PP_kinase PF02503.17 ACL95247.2 - 1.2e-57 194.8 0.3 1.8e-57 194.2 0.3 1.3 1 0 0 1 1 1 1 Polyphosphate kinase middle domain PP_kinase_N PF13089.6 ACL95247.2 - 1.8e-36 124.7 0.1 3.4e-36 123.8 0.1 1.5 1 0 0 1 1 1 1 Polyphosphate kinase N-terminal domain PLDc_2 PF13091.6 ACL95247.2 - 4.2e-11 42.8 0.0 0.00025 20.9 0.0 2.7 2 1 0 2 2 2 2 PLD-like domain Bac_DnaA PF00308.18 ACL95248.1 - 9.6e-06 25.6 0.0 0.0047 16.8 0.0 2.2 1 1 0 2 2 2 2 Bacterial dnaA protein AAA_33 PF13671.6 ACL95248.1 - 4.6e-05 23.6 0.0 7.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ACL95248.1 - 0.00019 21.9 4.2 0.00081 19.8 4.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 ACL95248.1 - 0.00037 20.3 0.0 0.0012 18.6 0.1 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 ACL95248.1 - 0.00068 20.1 0.0 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ACL95248.1 - 0.0024 18.2 0.0 0.0081 16.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 ACL95248.1 - 0.0026 17.8 0.0 0.0045 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 ACL95248.1 - 0.05 13.9 0.4 0.13 12.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ACL95248.1 - 0.062 13.8 0.0 0.075 13.6 0.0 1.3 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 ACL95248.1 - 0.073 13.0 0.1 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.16 ACL95248.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein Mg_chelatase PF01078.21 ACL95248.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 ACL95248.1 - 0.14 12.1 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain RNA_helicase PF00910.22 ACL95248.1 - 0.15 12.5 0.0 0.27 11.7 0.0 1.6 1 1 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 ACL95248.1 - 1.4 8.6 9.8 0.039 13.7 3.1 1.8 2 1 0 2 2 2 0 AAA domain HEPN_RiboL-PSP PF18735.1 ACL95250.1 - 0.00032 20.7 0.0 0.00046 20.2 0.0 1.4 1 0 0 1 1 1 1 RiboL-PSP-HEPN HEPN_MAE_28990 PF18737.1 ACL95250.1 - 0.026 14.4 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 MAE_28990/MAE_18760-like HEPN HEPN_Apea PF18739.1 ACL95250.1 - 0.041 14.3 0.0 0.077 13.4 0.0 1.6 1 1 0 1 1 1 0 Apea-like HEPN Rubella_E1 PF05748.11 ACL95250.1 - 0.16 10.8 0.1 0.22 10.4 0.1 1.1 1 0 0 1 1 1 0 Rubella membrane glycoprotein E1 EcsC PF12787.7 ACL95251.1 - 5.7e-64 216.1 0.0 6.9e-64 215.9 0.0 1.0 1 0 0 1 1 1 1 EcsC protein family DEDD_Tnp_IS110 PF01548.17 ACL95252.1 - 4.3e-20 72.1 0.0 8e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Transposase Transposase_20 PF02371.16 ACL95252.1 - 8e-18 64.5 0.2 1.9e-17 63.3 0.2 1.7 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family AP_endonuc_2 PF01261.24 ACL95252.1 - 0.098 12.1 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel DUF5560 PF17715.1 ACL95253.1 - 0.021 14.3 6.7 0.034 13.6 6.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5560) Acetyltransf_3 PF13302.7 ACL95254.1 - 1.4e-21 77.7 0.0 1.6e-21 77.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ACL95254.1 - 3.9e-10 40.0 0.0 4.8e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 ACL95254.1 - 0.00014 22.1 0.0 0.00016 21.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ACL95254.1 - 0.00035 20.9 0.0 0.0005 20.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ACL95254.1 - 0.00039 20.3 0.0 0.0008 19.3 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 ACL95254.1 - 0.0045 16.9 0.0 0.0059 16.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SecG PF03840.14 ACL95255.1 - 1.6e-16 60.1 9.0 2.1e-16 59.8 9.0 1.2 1 0 0 1 1 1 1 Preprotein translocase SecG subunit CTP_synth_N PF06418.14 ACL95256.1 - 1.6e-122 407.9 0.0 2.3e-122 407.4 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 ACL95256.1 - 8.5e-53 179.0 0.0 1.3e-52 178.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ACL95256.1 - 2.8e-07 30.5 0.0 0.00095 19.0 0.0 2.4 2 0 0 2 2 2 2 Peptidase C26 CbiA PF01656.23 ACL95256.1 - 0.034 14.2 0.0 0.048 13.7 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Ribosomal_L32p PF01783.23 ACL95257.1 - 2.2e-21 75.8 0.1 2.4e-21 75.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal L32p protein family Asp_protease_2 PF13650.6 ACL95258.1 - 6.9e-22 77.9 1.1 5.4e-14 52.6 0.4 2.4 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 ACL95258.1 - 8.6e-22 77.5 0.1 9.2e-15 55.0 0.1 2.3 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 ACL95258.1 - 0.00016 21.5 0.0 0.05 13.4 0.0 2.5 2 1 0 2 2 2 2 Aspartyl protease RVP PF00077.20 ACL95258.1 - 0.00068 19.9 0.0 0.0023 18.2 0.0 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease ECH_1 PF00378.20 ACL95259.2 - 2.1e-53 181.2 0.0 2.4e-53 181.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ACL95259.2 - 6.1e-28 98.3 0.1 7.5e-28 98.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase MutS_I PF01624.20 ACL95259.2 - 0.2 11.9 0.0 0.32 11.2 0.0 1.3 1 0 0 1 1 1 0 MutS domain I Enolase_C PF00113.22 ACL95260.1 - 1.9e-125 418.0 0.1 2.5e-125 417.6 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 ACL95260.1 - 2.2e-59 199.3 0.2 3.6e-59 198.6 0.2 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 ACL95260.1 - 8.2e-06 25.5 0.0 1.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 ACL95260.1 - 1.6e-05 24.2 0.1 5.4e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus DivIC PF04977.15 ACL95262.1 - 1.7e-18 66.1 0.0 2e-18 65.9 0.0 1.0 1 0 0 1 1 1 1 Septum formation initiator E1_dh PF00676.20 ACL95264.1 - 1.2e-99 333.0 0.7 1.4e-99 332.8 0.7 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 ACL95264.1 - 0.00012 21.4 0.1 0.00017 20.9 0.1 1.2 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 ACL95265.1 - 3.6e-49 166.8 0.2 6e-49 166.1 0.2 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ACL95265.1 - 2e-43 147.2 0.0 4.3e-43 146.1 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain Biotin_lipoyl PF00364.22 ACL95265.1 - 4.2e-23 81.0 1.3 1.1e-22 79.6 1.3 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 ACL95265.1 - 8.3e-08 31.9 0.0 2.2e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 Biotin-lipoyl like PFOR_II PF17147.4 ACL95265.1 - 0.00095 19.4 0.1 0.0024 18.1 0.1 1.7 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II RnfC_N PF13375.6 ACL95265.1 - 0.005 16.8 0.1 0.012 15.5 0.1 1.6 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Peptidase_M23 PF01551.22 ACL95265.1 - 0.011 15.9 0.2 0.26 11.5 0.0 2.7 2 1 0 2 2 2 0 Peptidase family M23 QRPTase_N PF02749.16 ACL95265.1 - 0.021 14.9 0.1 0.1 12.7 0.0 2.2 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain HlyD_3 PF13437.6 ACL95265.1 - 0.042 14.6 0.4 0.1 13.3 0.4 1.7 1 1 0 1 1 1 0 HlyD family secretion protein 2-oxoacid_dh PF00198.23 ACL95268.1 - 1.8e-82 276.3 0.3 2.3e-82 275.9 0.3 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 ACL95268.1 - 1.9e-22 78.9 6.8 2.7e-22 78.4 3.1 2.5 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 ACL95268.1 - 2.3e-15 56.6 0.6 6.4e-15 55.2 0.6 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 ACL95268.1 - 4.9e-08 32.7 0.0 2e-07 30.7 0.0 2.2 1 0 0 1 1 1 1 Biotin-lipoyl like RnfC_N PF13375.6 ACL95268.1 - 0.0013 18.7 0.3 0.0045 16.9 0.3 2.0 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain HlyD_3 PF13437.6 ACL95268.1 - 0.015 15.9 0.9 0.065 13.9 0.2 2.5 2 0 0 2 2 2 0 HlyD family secretion protein PYNP_C PF07831.13 ACL95268.1 - 0.026 14.2 0.2 0.079 12.6 0.2 1.8 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain Peptidase_M23 PF01551.22 ACL95268.1 - 0.03 14.5 0.2 0.14 12.4 0.1 2.2 1 1 1 2 2 2 0 Peptidase family M23 DUF2118 PF09891.9 ACL95268.1 - 0.079 12.9 0.2 0.16 11.9 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) YqfD PF06898.11 ACL95268.1 - 3.2 6.5 4.9 10 4.9 1.0 2.2 1 1 1 2 2 2 0 Putative stage IV sporulation protein YqfD GSHPx PF00255.19 ACL95269.1 - 3.9e-45 151.9 0.0 4.8e-45 151.6 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 ACL95269.1 - 3.4e-07 30.2 0.0 5.5e-07 29.5 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ACL95269.1 - 3.1e-05 23.7 0.0 0.00011 22.0 0.0 1.8 1 1 0 1 1 1 1 Redoxin DUF4174 PF13778.6 ACL95269.1 - 0.083 13.4 0.0 0.15 12.6 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4174) Pyr_redox_2 PF07992.14 ACL95270.1 - 4.8e-71 239.4 6.5 4.8e-71 239.4 6.5 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ACL95270.1 - 4.8e-36 123.4 3.2 1.3e-35 122.0 3.2 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 ACL95270.1 - 1.5e-22 80.0 14.4 7e-22 77.8 2.0 3.5 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ACL95270.1 - 6.9e-19 68.2 4.8 7.2e-13 48.5 0.2 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ACL95270.1 - 1.2e-10 41.1 10.3 2.6e-10 40.0 2.1 3.7 3 1 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 ACL95270.1 - 3.8e-10 39.4 16.8 1.2e-06 27.8 0.7 4.9 3 1 2 5 5 5 2 FAD binding domain HI0933_like PF03486.14 ACL95270.1 - 2e-08 33.4 14.8 0.00024 19.9 0.5 4.5 4 1 1 5 5 5 3 HI0933-like protein NAD_binding_8 PF13450.6 ACL95270.1 - 1.5e-07 31.5 5.6 0.013 15.7 0.5 3.7 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 ACL95270.1 - 3e-07 30.2 0.7 3e-07 30.2 0.7 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 ACL95270.1 - 2.7e-05 23.9 18.1 0.005 16.5 0.2 4.2 4 0 0 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 ACL95270.1 - 6.8e-05 22.2 1.4 0.0031 16.7 0.0 2.8 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 ACL95270.1 - 7.8e-05 22.1 7.3 0.0065 15.8 0.1 3.8 2 1 2 4 4 4 1 FAD binding domain 2-Hacid_dh_C PF02826.19 ACL95270.1 - 0.00012 21.5 2.0 0.015 14.7 0.0 3.0 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 ACL95270.1 - 0.00045 19.4 9.4 0.014 14.4 0.8 3.6 2 2 1 3 3 3 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 ACL95270.1 - 0.00091 18.6 5.7 0.45 9.8 1.1 2.9 2 1 1 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 ACL95270.1 - 0.0021 17.3 1.4 0.0034 16.6 0.1 2.0 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 ACL95270.1 - 0.0038 16.6 0.2 0.0038 16.6 0.2 2.5 2 1 1 3 3 3 1 Flavin containing amine oxidoreductase 3HCDH_N PF02737.18 ACL95270.1 - 0.022 14.6 1.2 0.022 14.6 1.2 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 ACL95270.1 - 0.098 13.2 0.7 1.3 9.6 0.0 2.5 3 0 0 3 3 2 0 XdhC Rossmann domain NAD_binding_9 PF13454.6 ACL95270.1 - 0.11 12.5 5.6 3.5 7.6 0.1 3.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 ACL95270.1 - 0.26 11.7 1.8 2.8 8.4 0.5 2.7 2 1 0 2 2 2 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 ACL95270.1 - 4 6.2 6.3 1.3 7.8 0.2 2.8 3 1 1 4 4 4 0 Tryptophan halogenase AMP-binding PF00501.28 ACL95272.1 - 1.4e-57 195.2 0.0 1.8e-57 194.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ACL95272.1 - 0.01 16.8 0.4 0.033 15.2 0.4 1.9 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Hydrolase_4 PF12146.8 ACL95273.1 - 7.2e-35 120.4 0.0 8.7e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ACL95273.1 - 8.5e-15 55.9 7.7 8.5e-15 55.9 7.7 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ACL95273.1 - 2.4e-12 47.1 0.0 4.3e-10 39.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Radical_SAM PF04055.21 ACL95274.1 - 3.5e-13 50.3 0.0 7.7e-13 49.1 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily LIAS_N PF16881.5 ACL95274.1 - 8.3e-09 35.8 0.0 2.2e-08 34.5 0.1 1.7 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Herpes_US12 PF05363.12 ACL95274.1 - 0.058 14.1 0.3 0.12 13.1 0.3 1.6 1 0 0 1 1 1 0 Herpesvirus US12 family Polyketide_cyc PF03364.20 ACL95275.1 - 3.1e-22 79.2 0.0 3.6e-22 79.0 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 ACL95275.1 - 1.7e-11 44.6 0.2 2e-11 44.3 0.2 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport CinA PF02464.17 ACL95276.1 - 2.3e-54 183.2 2.5 2.5e-54 183.0 2.5 1.0 1 0 0 1 1 1 1 Competence-damaged protein YgbB PF02542.16 ACL95277.1 - 1.3e-61 207.4 0.3 3.9e-61 205.9 0.0 1.8 2 0 0 2 2 2 1 YgbB family IspD PF01128.19 ACL95277.1 - 1.6e-49 168.6 0.3 2.3e-49 168.1 0.3 1.2 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transf_3 PF12804.7 ACL95277.1 - 1.7e-10 41.5 11.1 3.5e-10 40.5 11.1 1.7 1 1 0 1 1 1 1 MobA-like NTP transferase domain Dus PF01207.17 ACL95278.1 - 6.6e-90 301.3 0.0 7.7e-90 301.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) FMN_dh PF01070.18 ACL95278.1 - 0.0025 16.9 6.6 0.0048 16.0 6.3 1.6 1 1 0 1 1 1 1 FMN-dependent dehydrogenase IGPS PF00218.21 ACL95278.1 - 0.0061 15.8 0.0 0.026 13.7 0.0 1.8 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase ThiG PF05690.14 ACL95278.1 - 0.0065 15.8 1.8 0.0068 15.8 0.4 1.7 1 1 0 1 1 1 1 Thiazole biosynthesis protein ThiG SOR_SNZ PF01680.17 ACL95278.1 - 0.014 15.2 6.0 0.36 10.6 0.4 2.4 1 1 1 2 2 2 0 SOR/SNZ family NMO PF03060.15 ACL95278.1 - 0.02 14.3 2.4 0.02 14.3 2.4 1.9 2 0 0 2 2 2 0 Nitronate monooxygenase PEP_mutase PF13714.6 ACL95278.1 - 0.02 14.3 4.6 0.14 11.5 4.6 2.3 1 1 0 1 1 1 0 Phosphoenolpyruvate phosphomutase DHO_dh PF01180.21 ACL95278.1 - 0.034 13.4 0.1 0.34 10.1 0.1 2.0 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.21 ACL95278.1 - 0.066 12.7 0.6 0.13 11.6 0.5 1.5 1 1 0 1 1 1 0 Histidine biosynthesis protein Oxidored_FMN PF00724.20 ACL95278.1 - 0.069 12.4 0.1 0.83 8.9 0.2 2.4 2 1 0 2 2 2 0 NADH:flavin oxidoreductase / NADH oxidase family Glyoxalase PF00903.25 ACL95278.1 - 0.15 12.3 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ACL95278.1 - 0.3 11.9 3.2 6.6 7.6 0.5 2.8 2 1 0 2 2 2 0 Glyoxalase-like domain Trp_syntA PF00290.20 ACL95278.1 - 0.43 9.4 1.9 0.91 8.3 0.4 2.0 2 0 0 2 2 2 0 Tryptophan synthase alpha chain HATPase_c PF02518.26 ACL95279.1 - 3.7e-19 69.3 0.0 6.9e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ACL95279.1 - 1.7e-11 44.0 0.1 4.3e-11 42.7 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 ACL95279.1 - 4.6e-06 26.5 0.1 1.5e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 PAS domain MLTR_LBD PF17765.1 ACL95279.1 - 0.00013 22.1 0.7 0.0015 18.7 0.1 2.2 2 0 0 2 2 2 1 MmyB-like transcription regulator ligand binding domain PAS PF00989.25 ACL95279.1 - 0.00036 20.5 0.0 0.0018 18.3 0.0 2.2 3 0 0 3 3 3 1 PAS fold HATPase_c_5 PF14501.6 ACL95279.1 - 0.00058 19.7 0.0 0.0066 16.3 0.0 2.2 1 1 0 1 1 1 1 GHKL domain PAS_4 PF08448.10 ACL95279.1 - 0.0007 19.8 0.1 0.0024 18.1 0.0 2.0 2 0 0 2 2 2 1 PAS fold DUF1688 PF07958.11 ACL95279.1 - 0.017 13.9 0.0 0.023 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1688) HATPase_c_2 PF13581.6 ACL95279.1 - 0.027 14.4 0.0 0.061 13.3 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Sigma54_activat PF00158.26 ACL95280.1 - 4.1e-45 153.5 0.0 1.2e-44 152.0 0.0 1.8 2 0 0 2 2 2 1 Sigma-54 interaction domain Response_reg PF00072.24 ACL95280.1 - 2.9e-24 85.4 0.0 5.9e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activ_2 PF14532.6 ACL95280.1 - 4.4e-23 81.9 0.0 7.4e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 ACL95280.1 - 7.8e-14 51.2 0.4 1.7e-13 50.1 0.4 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 ACL95280.1 - 7.9e-06 25.9 0.0 2e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 ACL95280.1 - 2e-05 24.8 0.0 0.00019 21.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 ACL95280.1 - 9.7e-05 22.8 0.0 0.00022 21.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ACL95280.1 - 0.00078 19.9 0.4 0.0021 18.5 0.4 1.9 1 1 0 1 1 1 1 AAA ATPase domain Phage_NinH PF06322.11 ACL95280.1 - 0.0024 17.7 0.2 0.0087 15.9 0.1 1.9 2 0 0 2 2 2 1 Phage NinH protein IstB_IS21 PF01695.17 ACL95280.1 - 0.015 15.1 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein HTH_30 PF13556.6 ACL95280.1 - 0.037 13.8 0.1 0.11 12.3 0.1 1.8 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Mg_chelatase PF01078.21 ACL95280.1 - 0.051 13.0 0.0 7.9 5.8 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MCM PF00493.23 ACL95280.1 - 0.062 12.4 0.0 0.16 11.0 0.0 1.6 1 1 0 1 1 1 0 MCM P-loop domain FleQ PF06490.11 ACL95280.1 - 0.096 13.1 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ HATPase_c PF02518.26 ACL95281.1 - 1.4e-15 57.8 0.0 3.5e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 ACL95281.1 - 4.7e-10 39.7 0.3 4.7e-10 39.7 0.3 2.9 4 0 0 4 4 4 1 HAMP domain HisKA PF00512.25 ACL95281.1 - 1.8e-09 37.5 0.1 7.2e-09 35.6 0.0 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_7 PF12860.7 ACL95281.1 - 6.7e-06 26.2 0.0 0.00078 19.6 0.0 2.8 1 1 0 1 1 1 1 PAS fold HATPase_c_2 PF13581.6 ACL95281.1 - 1.2e-05 25.3 0.1 3e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PAS PF00989.25 ACL95281.1 - 3.9e-05 23.6 0.0 0.00011 22.1 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 ACL95281.1 - 0.0002 21.3 0.0 0.00056 19.9 0.0 1.7 1 0 0 1 1 1 1 PAS domain HATPase_c_5 PF14501.6 ACL95281.1 - 0.0066 16.3 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 GHKL domain Sigma54_activat PF00158.26 ACL95282.1 - 1.2e-46 158.5 0.0 1.7e-46 158.0 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 ACL95282.1 - 2.1e-28 98.7 0.2 3.9e-28 97.9 0.2 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activ_2 PF14532.6 ACL95282.1 - 8.1e-23 81.1 0.0 1.8e-22 79.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 ACL95282.1 - 7.3e-10 38.5 0.5 2.4e-09 36.8 0.2 2.1 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 ACL95282.1 - 1.7e-05 24.8 0.0 4.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 ACL95282.1 - 5.9e-05 22.5 1.0 0.27 10.6 0.1 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA PF00004.29 ACL95282.1 - 0.0033 17.8 0.0 0.007 16.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ACL95282.1 - 0.038 14.4 0.3 0.12 12.8 0.2 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 ACL95282.1 - 0.063 13.0 0.2 0.23 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain B12-binding PF02310.19 ACL95282.1 - 0.066 13.3 0.1 0.25 11.4 0.0 1.9 2 0 0 2 2 2 0 B12 binding domain AAA_25 PF13481.6 ACL95282.1 - 0.07 12.7 5.2 0.21 11.1 0.2 3.0 2 1 1 3 3 3 0 AAA domain AAA_19 PF13245.6 ACL95282.1 - 0.087 13.2 0.4 5.8 7.2 0.0 2.6 3 0 0 3 3 3 0 AAA domain Aminotran_4 PF01063.19 ACL95283.1 - 8e-38 130.5 0.0 9.4e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Hfq PF17209.3 ACL95284.1 - 2.6e-33 113.5 0.1 3e-33 113.2 0.1 1.0 1 0 0 1 1 1 1 Hfq protein GTP-bdg_M PF16360.5 ACL95285.1 - 3.3e-29 101.3 8.3 6.2e-29 100.4 8.3 1.5 1 0 0 1 1 1 1 GTP-binding GTPase Middle Region GTP-bdg_N PF13167.6 ACL95285.1 - 5.3e-28 97.5 0.9 1.4e-27 96.2 0.4 2.0 2 0 0 2 2 2 1 GTP-binding GTPase N-terminal MMR_HSR1 PF01926.23 ACL95285.1 - 3e-21 75.6 0.0 1.6e-20 73.2 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ACL95285.1 - 2.6e-05 23.8 0.4 0.00018 21.0 0.1 2.3 2 1 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 ACL95285.1 - 0.0012 18.8 0.0 0.17 11.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 ACL95285.1 - 0.0016 18.6 0.0 0.0075 16.3 0.0 1.8 1 1 1 2 2 2 1 Dynamin family ATP_bind_1 PF03029.17 ACL95285.1 - 0.004 17.0 0.0 0.9 9.3 0.0 2.3 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 ACL95285.1 - 0.0047 17.3 0.2 0.014 15.7 0.2 1.8 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 ACL95285.1 - 0.027 15.0 0.0 0.15 12.6 0.0 2.3 2 1 0 2 2 2 0 ABC transporter GTP_EFTU PF00009.27 ACL95285.1 - 0.048 13.2 0.1 4.8 6.7 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain SRPRB PF09439.10 ACL95285.1 - 0.05 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Ras PF00071.22 ACL95285.1 - 0.19 11.3 0.0 0.86 9.2 0.0 1.9 1 1 0 1 1 1 0 Ras family MazG PF03819.17 ACL95286.2 - 4.3e-43 145.4 1.1 1.5e-29 102.0 0.0 2.3 2 0 0 2 2 2 2 MazG nucleotide pyrophosphohydrolase domain PRA-PH PF01503.17 ACL95286.2 - 2e-12 47.4 1.1 6.2e-06 26.6 0.2 2.5 2 0 0 2 2 2 2 Phosphoribosyl-ATP pyrophosphohydrolase MazG-like PF12643.7 ACL95286.2 - 6.8e-05 23.0 0.1 0.0013 18.9 0.0 2.4 2 0 0 2 2 2 1 MazG-like family Cytochrom_C_2 PF01322.20 ACL95286.2 - 0.016 16.1 0.6 4.9 8.1 0.3 3.0 2 1 1 3 3 3 0 Cytochrome C' PKS_DE PF18369.1 ACL95286.2 - 0.26 11.9 3.0 3.9 8.1 0.2 3.2 3 0 0 3 3 3 0 Polyketide synthase dimerisation element domain Cytochrom_B562 PF07361.11 ACL95286.2 - 1.4 9.6 3.9 6.7 7.4 1.0 3.2 3 1 0 3 3 3 0 Cytochrome b562 MFS_2 PF13347.6 ACL95287.1 - 7.6e-74 248.8 28.7 8.6e-74 248.6 28.7 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 ACL95287.1 - 1.1e-20 74.0 37.5 1.1e-20 74.0 37.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 ACL95287.1 - 6.3e-11 41.8 8.0 1.5e-05 24.0 2.1 2.9 1 1 1 2 2 2 2 MFS_1 like family DUF2160 PF09928.9 ACL95287.1 - 0.012 15.9 0.4 0.72 10.2 0.1 3.0 2 0 0 2 2 2 0 Predicted small integral membrane protein (DUF2160) O-antigen_lig PF13425.6 ACL95287.1 - 0.62 8.8 5.5 0.13 11.0 2.1 1.5 2 0 0 2 2 2 0 O-antigen ligase like membrane protein LacY_symp PF01306.19 ACL95287.1 - 0.71 8.6 15.8 1.3 7.7 2.3 2.5 2 1 0 2 2 2 0 LacY proton/sugar symporter Rho_RNA_bind PF07497.12 ACL95288.1 - 0.17 11.7 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Rho termination factor, RNA-binding domain TonB_dep_Rec PF00593.24 ACL95291.1 - 2.5e-57 195.8 24.8 3.5e-57 195.3 23.7 1.6 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 ACL95291.1 - 2.7e-24 85.8 1.3 8.7e-24 84.2 1.3 1.9 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 ACL95291.1 - 2e-09 36.9 0.0 7.9e-08 31.7 0.0 2.4 2 0 0 2 2 2 1 Outer membrane protein beta-barrel family BBP2 PF07642.11 ACL95291.1 - 0.85 8.7 9.5 0.049 12.8 1.2 2.5 2 2 0 2 2 2 0 Putative beta-barrel porin-2, OmpL-like. bbp2 GATase_3 PF07685.14 ACL95292.1 - 2.2e-56 190.6 0.0 3e-56 190.2 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.23 ACL95292.1 - 1.5e-15 57.4 0.0 2.2e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 ACL95292.1 - 1.5e-15 57.5 0.0 5.4e-15 55.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF2939 PF11159.8 ACL95293.1 - 1.7e-30 105.3 1.5 2.3e-30 104.8 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2939) Peripla_BP_3 PF13377.6 ACL95294.1 - 6e-41 140.5 0.2 8.8e-39 133.5 0.1 2.2 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 ACL95294.1 - 2.1e-24 86.4 0.0 2.8e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 ACL95294.1 - 7.6e-16 57.6 1.0 7.6e-16 57.6 1.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 ACL95294.1 - 7.7e-16 58.4 0.0 1.2e-15 57.9 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain HTH_31 PF13560.6 ACL95294.1 - 0.00087 19.6 0.2 0.0032 17.8 0.2 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain Crp PF00325.20 ACL95294.1 - 0.043 13.5 0.2 0.13 12.0 0.2 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family HTH_3 PF01381.22 ACL95294.1 - 0.067 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix HTH_Crp_2 PF13545.6 ACL95294.1 - 0.093 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain TonB_dep_Rec PF00593.24 ACL95295.1 - 1e-30 108.1 18.4 1e-30 108.1 18.4 2.2 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 ACL95295.1 - 9.4e-14 51.9 0.7 9.4e-14 51.9 0.7 2.3 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 ACL95295.1 - 7.4e-08 31.8 4.8 0.00069 18.7 0.0 3.5 3 0 0 3 3 3 2 Outer membrane protein beta-barrel family Trp_halogenase PF04820.14 ACL95296.1 - 3.2e-200 665.8 0.0 3.7e-200 665.5 0.0 1.0 1 0 0 1 1 1 1 Tryptophan halogenase DAO PF01266.24 ACL95296.1 - 2.4e-05 24.1 0.1 3.6e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ACL95296.1 - 0.046 13.1 0.8 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Glyco_hydro_3_C PF01915.22 ACL95297.2 - 7.8e-61 205.6 0.1 1.8e-60 204.4 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ACL95297.2 - 3e-47 161.6 0.0 5e-47 160.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ACL95297.2 - 7.8e-15 54.7 0.0 1.7e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_30 PF02055.16 ACL95298.1 - 8.3e-35 120.4 0.0 1.1e-34 120.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 ACL95298.1 - 1.6e-14 53.9 0.2 2.7e-14 53.1 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 ACL95298.1 - 2.1e-07 30.5 0.0 4.2e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 ACL95298.1 - 0.00011 22.0 0.0 0.0087 15.7 0.0 2.1 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 FtsX PF02687.21 ACL95299.1 - 1.5e-14 54.2 17.0 4.1e-11 43.2 5.6 5.5 6 1 0 6 6 6 2 FtsX-like permease family MacB_PCD PF12704.7 ACL95299.1 - 3.4e-09 37.3 16.1 1.1e-05 25.9 0.8 3.1 3 0 0 3 3 3 2 MacB-like periplasmic core domain Asp_protease_2 PF13650.6 ACL95299.1 - 0.015 15.9 0.0 0.086 13.5 0.0 2.3 2 0 0 2 2 2 0 Aspartyl protease Molydop_binding PF01568.21 ACL95299.1 - 0.097 12.7 0.0 0.3 11.1 0.0 1.8 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain ABC_tran PF00005.27 ACL95300.1 - 1e-32 113.5 0.0 1.2e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ACL95300.1 - 1.4e-06 27.9 0.0 0.0065 15.9 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ACL95300.1 - 3.4e-05 23.8 0.1 0.21 11.4 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ACL95300.1 - 0.00074 19.2 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 ACL95300.1 - 0.03 14.7 1.1 0.057 13.8 1.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 ACL95300.1 - 0.079 12.9 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 ACL95300.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein SbcCD_C PF13558.6 ACL95300.1 - 0.18 12.1 0.3 2 8.7 0.3 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Lipase_GDSL_2 PF13472.6 ACL95301.1 - 3e-23 83.1 0.2 3.8e-23 82.8 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ACL95301.1 - 4.8e-12 46.3 0.0 6.9e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase OSK PF17182.4 ACL95301.1 - 0.004 16.4 0.0 0.0051 16.1 0.0 1.1 1 0 0 1 1 1 1 OSK domain ORF6C PF10552.9 ACL95301.1 - 0.066 13.3 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 ORF6C domain HTH_38 PF13936.6 ACL95302.1 - 1e-16 60.4 5.3 2.1e-16 59.4 3.3 2.5 3 0 0 3 3 3 1 Helix-turn-helix domain rve PF00665.26 ACL95302.1 - 6.2e-12 45.8 0.0 1.2e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain HTH_23 PF13384.6 ACL95302.1 - 3.8e-07 29.7 3.3 2e-06 27.4 0.9 2.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.6 ACL95302.1 - 2.3e-06 28.1 3.6 2.3e-06 28.1 3.6 3.8 3 2 1 4 4 4 1 Homeodomain-like domain AbiEi_4 PF13338.6 ACL95302.1 - 0.03 14.5 0.2 0.03 14.5 0.2 2.2 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin HTH_Tnp_Tc3_1 PF11427.8 ACL95302.1 - 0.16 11.9 1.8 18 5.3 0.0 2.8 3 0 0 3 3 3 0 Tc3 transposase DUF2083 PF09856.9 ACL95305.1 - 5.5e-61 205.0 0.0 1e-60 204.1 0.0 1.5 1 0 0 1 1 1 1 Predicted transcriptional regulator (DUF2083) Peptidase_M78 PF06114.13 ACL95305.1 - 1.2e-17 63.9 0.0 2.6e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 IrrE N-terminal-like domain HTH_31 PF13560.6 ACL95305.1 - 2e-12 47.2 4.2 2e-12 47.2 4.2 3.5 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_19 PF12844.7 ACL95305.1 - 3.3e-11 43.0 0.4 1.5e-09 37.7 0.1 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_3 PF01381.22 ACL95305.1 - 5.6e-11 42.3 1.1 3.5e-10 39.8 0.3 2.5 2 0 0 2 2 2 1 Helix-turn-helix HTH_26 PF13443.6 ACL95305.1 - 0.0026 18.1 0.2 0.0068 16.8 0.2 1.7 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_37 PF13744.6 ACL95305.1 - 0.0032 17.4 0.2 0.018 15.0 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_25 PF13413.6 ACL95305.1 - 0.0098 15.7 2.0 0.043 13.7 0.3 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain DUF3509 PF12021.8 ACL95305.1 - 0.1 12.4 0.3 15 5.4 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3509) ICL PF00463.21 ACL95306.1 - 3.5e-43 147.9 1.1 1.1e-18 67.0 0.1 3.1 3 0 0 3 3 3 3 Isocitrate lyase family PEP_mutase PF13714.6 ACL95306.1 - 3.4e-12 46.3 0.6 2.1e-11 43.8 0.7 2.0 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Malate_synthase PF01274.22 ACL95308.1 - 5.9e-198 658.4 0.0 6.6e-198 658.2 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Phage_integrase PF00589.22 ACL95309.1 - 1.3e-14 54.4 0.0 1.6e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family Response_reg PF00072.24 ACL95310.1 - 2.3e-20 72.8 0.0 3.3e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain HTH_8 PF02954.19 ACL95310.1 - 1e-11 44.4 0.4 2.5e-11 43.2 0.4 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family HTH_30 PF13556.6 ACL95310.1 - 7.4e-06 25.7 0.5 7.4e-06 25.7 0.5 1.9 2 0 0 2 2 2 1 PucR C-terminal helix-turn-helix domain HTH_28 PF13518.6 ACL95310.1 - 0.025 14.7 0.4 0.088 13.0 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 ACL95310.1 - 0.03 14.1 0.1 0.086 12.7 0.1 1.8 1 0 0 1 1 1 0 Homeodomain-like domain Phage_NinH PF06322.11 ACL95310.1 - 0.033 14.1 0.9 0.053 13.4 0.1 1.7 2 0 0 2 2 2 0 Phage NinH protein HTH_38 PF13936.6 ACL95310.1 - 0.05 13.4 0.3 0.1 12.4 0.3 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2388 PF09498.10 ACL95310.1 - 0.072 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2388) DXP_reductoisom PF02670.16 ACL95310.1 - 0.12 13.0 0.1 0.87 10.3 0.1 2.0 1 1 1 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase HATPase_c PF02518.26 ACL95311.1 - 1.4e-10 41.6 0.0 2.4e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ACL95311.1 - 9.2e-05 22.4 0.0 0.0003 20.8 0.0 1.9 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 ACL95311.1 - 0.00017 21.6 0.0 0.00041 20.3 0.0 1.5 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 ACL95311.1 - 0.00093 19.0 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CcmD PF04995.14 ACL95311.1 - 4.1 7.6 7.6 7.2 6.8 0.3 3.1 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) SURF1 PF02104.15 ACL95312.1 - 1.6e-41 142.4 0.3 1.9e-41 142.2 0.3 1.0 1 0 0 1 1 1 1 SURF1 family DUF308 PF03729.13 ACL95312.1 - 0.046 14.1 1.7 8.7 6.8 0.4 2.5 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) COX4_pro PF03626.14 ACL95313.1 - 1.4e-17 63.9 16.2 1.7e-17 63.6 16.2 1.1 1 0 0 1 1 1 1 Prokaryotic Cytochrome C oxidase subunit IV DUF846 PF05832.12 ACL95313.1 - 0.046 13.8 6.1 1.6 8.8 2.1 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF846) SID-1_RNA_chan PF13965.6 ACL95313.1 - 0.062 11.7 2.5 0.071 11.5 2.5 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MtrF PF09472.10 ACL95313.1 - 0.073 12.5 0.4 0.073 12.5 0.4 2.4 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DUF1229 PF06797.11 ACL95313.1 - 0.16 12.2 1.5 0.2 11.9 0.3 1.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1229) PepSY_TM PF03929.16 ACL95313.1 - 0.19 11.4 3.9 0.74 9.4 4.5 1.6 1 1 1 2 2 2 0 PepSY-associated TM region MARVEL PF01284.23 ACL95313.1 - 0.23 11.5 9.5 0.41 10.7 9.6 1.3 1 1 0 1 1 1 0 Membrane-associating domain HXXEE PF13787.6 ACL95313.1 - 0.56 11.0 13.8 0.12 13.1 8.9 1.9 1 1 1 2 2 2 0 Protein of unknown function with HXXEE motif Sigma_reg_N PF13800.6 ACL95313.1 - 0.7 10.2 0.1 0.7 10.2 0.1 2.5 2 1 1 3 3 3 0 Sigma factor regulator N-terminal YrhC PF14143.6 ACL95313.1 - 2.9 8.0 6.3 0.76 9.9 2.1 2.0 1 1 1 2 2 2 0 YrhC-like protein COX3 PF00510.18 ACL95314.1 - 3.7e-14 53.2 12.1 5.4e-14 52.6 12.1 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III COX1 PF00115.20 ACL95315.1 - 1.5e-138 462.3 69.5 1.5e-138 462.3 69.5 2.4 3 0 0 3 3 3 1 Cytochrome C and Quinol oxidase polypeptide I COX_ARM PF06481.14 ACL95316.1 - 4.7e-15 55.2 0.0 7.8e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 COX Aromatic Rich Motif COX2 PF00116.20 ACL95316.1 - 1.9e-06 27.8 0.0 4.4e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain Cyt_bd_oxida_II PF02322.15 ACL95316.1 - 0.024 14.0 1.5 0.039 13.3 1.5 1.2 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II DUF4079 PF13301.6 ACL95316.1 - 0.055 13.6 0.1 0.086 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) COX2_TM PF02790.15 ACL95316.1 - 0.057 13.6 2.4 0.096 12.8 2.4 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain DUF1461 PF07314.11 ACL95316.1 - 0.1 12.5 0.7 0.15 12.0 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) MFS_1 PF07690.16 ACL95317.1 - 3.9e-13 49.0 50.9 3.9e-13 49.0 50.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ACL95317.1 - 1.7e-11 43.7 11.2 1.7e-11 43.7 11.2 2.6 1 1 0 2 2 2 2 Sugar (and other) transporter DUF2946 PF11162.8 ACL95318.1 - 9.5e-08 32.7 4.3 1.3e-07 32.3 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2946) GntR PF00392.21 ACL95319.1 - 1.5e-15 56.6 0.7 3.4e-15 55.4 0.3 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family FCD PF07729.12 ACL95319.1 - 9.6e-15 55.1 3.2 1.7e-14 54.3 3.2 1.4 1 0 0 1 1 1 1 FCD domain MarR_2 PF12802.7 ACL95319.1 - 0.00036 20.4 1.2 0.0021 17.9 0.1 2.7 3 0 0 3 3 3 1 MarR family HTH_24 PF13412.6 ACL95319.1 - 0.0022 17.5 0.0 0.0062 16.1 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 ACL95319.1 - 0.0025 17.8 0.0 0.0067 16.4 0.0 1.8 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_CodY PF08222.11 ACL95319.1 - 0.0054 16.3 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 CodY helix-turn-helix domain TrmB PF01978.19 ACL95319.1 - 0.0078 16.1 0.0 0.026 14.4 0.0 1.9 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Fe_dep_repress PF01325.19 ACL95319.1 - 0.04 14.1 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Sod_Fe_C PF02777.18 ACL95320.1 - 3.1e-37 126.9 0.1 4.5e-37 126.3 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 ACL95320.1 - 4.1e-26 91.3 1.2 4.1e-26 91.2 0.1 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain OpcA PF07239.11 ACL95320.1 - 0.47 10.1 1.6 19 4.8 0.0 2.1 2 0 0 2 2 2 0 Outer membrane protein OpcA TonB_dep_Rec PF00593.24 ACL95321.1 - 5.5e-54 184.8 13.5 7.5e-54 184.3 11.3 1.9 1 1 1 2 2 2 2 TonB dependent receptor Plug PF07715.15 ACL95321.1 - 2.7e-14 53.6 0.1 6.6e-14 52.4 0.1 1.6 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OMP_b-brl PF13505.6 ACL95321.1 - 0.055 13.6 5.2 0.48 10.5 2.3 3.3 1 1 2 4 4 4 0 Outer membrane protein beta-barrel domain DJ-1_PfpI PF01965.24 ACL95322.1 - 1.3e-21 77.1 0.0 1.9e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI PF01965.24 ACL95323.1 - 1.6e-27 96.3 0.1 2.3e-27 95.8 0.1 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Flu_NS1 PF00600.19 ACL95323.1 - 0.079 12.5 0.0 0.3 10.6 0.0 1.9 2 1 1 3 3 3 0 Influenza non-structural protein (NS1) TonB_dep_Rec PF00593.24 ACL95324.1 - 1.3e-33 117.7 20.4 1.3e-33 117.7 20.4 1.8 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 ACL95324.1 - 2.2e-15 57.1 0.6 4.8e-15 56.0 0.2 1.8 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain RtxA PF07634.11 ACL95324.1 - 0.16 12.5 0.5 21 5.9 0.1 3.0 2 0 0 2 2 2 0 RtxA repeat PepSY_TM PF03929.16 ACL95325.1 - 2.9e-48 165.0 12.7 3.5e-48 164.7 12.7 1.1 1 0 0 1 1 1 1 PepSY-associated TM region PepSY PF03413.19 ACL95325.1 - 3.8e-11 43.4 0.0 7.7e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain DUF4079 PF13301.6 ACL95325.1 - 0.00028 21.0 1.6 0.76 9.9 0.1 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF4079) B12D PF06522.11 ACL95325.1 - 0.014 15.2 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Cytochrom_B561 PF03188.16 ACL95325.1 - 0.017 15.2 0.2 3.5 7.8 0.0 2.5 2 1 0 2 2 2 0 Eukaryotic cytochrome b561 OEP PF02321.18 ACL95328.1 - 3.5e-43 147.6 30.6 7.3e-23 81.4 9.9 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein TetR_N PF00440.23 ACL95329.1 - 3.3e-12 46.0 1.6 7.1e-12 44.9 1.6 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_27 PF17935.1 ACL95329.1 - 5.1e-12 45.8 0.1 8.6e-12 45.1 0.1 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_24 PF17932.1 ACL95329.1 - 0.00041 20.6 0.3 0.00086 19.6 0.3 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_17 PF17922.1 ACL95329.1 - 0.1 12.7 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HlyD_D23 PF16576.5 ACL95330.1 - 9.6e-13 47.8 3.2 2.3e-12 46.6 3.2 1.6 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 ACL95330.1 - 6.6e-10 39.6 5.7 2.5e-06 28.1 0.4 2.9 3 1 0 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 ACL95330.1 - 9.3e-08 31.8 15.1 1.2e-07 31.4 0.6 3.4 4 0 0 4 4 4 2 Biotin-lipoyl like Biotin_lipoyl PF00364.22 ACL95330.1 - 1.4e-05 24.8 1.2 0.12 12.3 0.1 3.0 3 0 0 3 3 3 2 Biotin-requiring enzyme PTS_EIIA_1 PF00358.20 ACL95330.1 - 0.014 15.1 0.0 1 9.1 0.0 2.5 2 0 0 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 PASTA PF03793.19 ACL95330.1 - 0.028 14.3 0.7 1.6 8.6 0.2 2.5 2 0 0 2 2 2 0 PASTA domain ACR_tran PF00873.19 ACL95331.1 - 1.4e-142 476.6 10.0 1.9e-142 476.1 10.0 1.1 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family SecD_SecF PF02355.16 ACL95331.1 - 0.16 11.3 29.3 0.18 11.2 8.5 2.4 2 0 0 2 2 2 0 Protein export membrane protein 2H-phosphodiest PF08975.10 ACL95333.1 - 4.3e-42 142.8 0.0 1.1e-41 141.5 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1868) LigT_PEase PF02834.16 ACL95333.1 - 0.0023 18.1 0.0 0.018 15.2 0.0 2.3 2 0 0 2 2 2 1 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.6 ACL95333.1 - 0.017 15.0 0.1 0.051 13.5 0.1 1.8 1 1 1 2 2 2 0 2'-5' RNA ligase superfamily TonB_dep_Rec PF00593.24 ACL95334.1 - 2.5e-40 139.8 27.9 2.5e-40 139.8 27.9 2.5 1 1 0 2 2 2 1 TonB dependent receptor OMP_b-brl_3 PF14905.6 ACL95334.1 - 1.5e-22 80.1 4.3 2.3e-22 79.6 0.1 2.5 2 1 0 2 2 2 1 Outer membrane protein beta-barrel family Plug PF07715.15 ACL95334.1 - 1e-15 58.2 0.8 3.1e-15 56.7 0.8 1.9 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain ROK PF00480.20 ACL95335.1 - 5.5e-22 78.6 0.0 6e-21 75.2 0.0 2.0 1 1 0 1 1 1 1 ROK family MarR_2 PF12802.7 ACL95335.1 - 4.8e-06 26.4 1.8 1.1e-05 25.2 1.8 1.6 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 ACL95335.1 - 6.7e-05 22.4 0.2 0.00012 21.6 0.2 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 ACL95335.1 - 0.00029 20.7 0.0 0.0006 19.7 0.0 1.5 1 0 0 1 1 1 1 MarR family DUF742 PF05331.11 ACL95335.1 - 0.00091 19.0 0.3 0.0042 16.9 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF742) HTH_Crp_2 PF13545.6 ACL95335.1 - 0.0019 18.1 0.2 0.0068 16.4 0.2 1.9 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain DprA_WH PF17782.1 ACL95335.1 - 0.0041 17.2 2.0 0.024 14.8 0.2 2.8 2 0 0 2 2 2 1 DprA winged helix domain HTH_IclR PF09339.10 ACL95335.1 - 0.013 15.2 0.4 0.013 15.2 0.4 2.0 2 0 0 2 2 2 0 IclR helix-turn-helix domain Crp PF00325.20 ACL95335.1 - 0.049 13.3 0.1 0.14 11.8 0.1 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family HTH_AsnC-type PF13404.6 ACL95335.1 - 0.057 13.3 0.7 0.13 12.1 0.7 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain CorA PF01544.18 ACL95338.1 - 0.039 13.3 0.1 0.045 13.1 0.1 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF772 PF05598.11 ACL95339.1 - 4e-18 65.2 0.4 8.8e-18 64.1 0.0 1.8 2 0 0 2 2 2 1 Transposase domain (DUF772) DDE_Tnp_1_6 PF13751.6 ACL95339.1 - 4.1e-14 52.9 1.5 9e-14 51.8 0.0 2.1 2 0 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 ACL95339.1 - 5.8e-13 49.0 0.0 3.2e-12 46.6 0.0 2.1 1 1 0 1 1 1 1 Transposase DDE domain Fmp27_WPPW PF10359.9 ACL95339.1 - 0.012 14.5 0.5 0.016 14.1 0.5 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF501 PF04417.12 ACL95339.1 - 0.089 12.6 0.3 1 9.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF501) UPF0193 PF05250.11 ACL95339.1 - 0.18 11.6 1.8 0.31 10.8 1.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0193) CLZ PF16526.5 ACL95339.1 - 0.28 11.6 4.9 0.53 10.7 1.8 2.5 1 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MerR-DNA-bind PF09278.11 ACL95339.1 - 2.1 8.9 5.6 3.3 8.3 3.9 2.2 1 1 1 2 2 2 0 MerR, DNA binding Acyl-CoA_dh_1 PF00441.24 ACL95340.1 - 1.9e-46 158.0 4.6 3.1e-46 157.3 4.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ACL95340.1 - 7.6e-28 96.6 0.0 1.5e-27 95.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ACL95340.1 - 3.3e-23 82.5 0.0 9e-23 81.1 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ACL95340.1 - 6.2e-23 81.6 5.3 6.2e-23 81.6 5.3 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 ACL95340.1 - 0.084 12.5 0.4 0.24 11.0 0.4 1.7 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal FMO-like PF00743.19 ACL95341.1 - 4.1e-13 48.6 0.0 2e-11 43.1 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ACL95341.1 - 3.4e-07 30.4 0.3 1.4e-06 28.4 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ACL95341.1 - 1.1e-06 28.1 0.0 3.3e-06 26.6 0.0 1.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ACL95341.1 - 1.6e-05 24.3 0.0 7.3e-05 22.1 0.0 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ACL95341.1 - 0.051 12.3 1.1 6.7 5.3 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein 4HBT_3 PF13622.6 ACL95342.2 - 9.9e-32 111.1 0.1 1.3e-31 110.8 0.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 ACL95342.2 - 0.001 19.4 0.1 0.077 13.4 0.0 2.7 2 2 0 2 2 2 1 Thioesterase superfamily AMP-binding PF00501.28 ACL95343.1 - 9.4e-55 185.9 0.0 1.3e-54 185.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ACL95343.1 - 1.6e-15 57.8 0.6 5.9e-15 56.0 0.6 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain NAPRTase_N PF17767.1 ACL95343.1 - 0.023 15.1 0.0 0.052 13.9 0.0 1.5 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Oxidored_FMN PF00724.20 ACL95344.1 - 1.4e-55 189.0 0.0 1.6e-54 185.5 0.0 2.0 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family adh_short_C2 PF13561.6 ACL95345.1 - 1.8e-48 165.1 7.5 2.1e-48 164.9 7.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ACL95345.1 - 7.2e-43 146.3 2.5 8.9e-43 146.0 2.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 ACL95345.1 - 2.9e-06 26.9 0.7 4.4e-06 26.3 0.7 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 ACL95345.1 - 0.00014 21.9 2.4 0.00019 21.4 2.4 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 ACL95345.1 - 0.017 14.7 0.3 0.017 14.7 0.3 1.5 2 0 0 2 2 2 0 NmrA-like family 3Beta_HSD PF01073.19 ACL95345.1 - 0.037 13.0 0.1 0.045 12.8 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ACL95345.1 - 0.099 11.7 0.9 0.16 11.0 0.9 1.4 1 1 0 1 1 1 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 ACL95345.1 - 0.1 11.7 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short_C2 PF13561.6 ACL95346.1 - 1.4e-06 28.1 0.0 0.00083 19.0 0.0 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase HCV_core PF01542.18 ACL95346.1 - 0.23 11.8 3.2 0.81 10.1 1.0 2.2 1 1 1 2 2 2 0 Hepatitis C virus core protein SGL PF08450.12 ACL95347.1 - 8e-75 251.6 0.0 9.3e-75 251.4 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Lactonase PF10282.9 ACL95347.1 - 0.089 12.0 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Phytase-like PF13449.6 ACL95347.1 - 0.13 12.2 0.0 7.3 6.4 0.0 2.4 2 1 0 2 2 2 0 Esterase-like activity of phytase Acyl-CoA_dh_1 PF00441.24 ACL95348.1 - 2.3e-24 86.3 2.5 3.2e-24 85.9 2.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ACL95348.1 - 2.5e-24 86.1 0.0 6e-24 84.9 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ACL95348.1 - 5.4e-20 71.4 0.0 9e-20 70.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain HpaB_N PF11794.8 ACL95348.1 - 0.19 11.4 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Acyl-CoA_dh_1 PF00441.24 ACL95349.1 - 3.4e-22 79.3 7.7 7.6e-22 78.1 7.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ACL95349.1 - 6.1e-18 65.5 0.2 6.1e-18 65.5 0.2 2.3 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ACL95349.1 - 1.3e-11 44.5 0.0 2.9e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ACL95349.1 - 0.009 16.3 8.1 0.009 16.3 8.1 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 ACL95349.1 - 0.014 15.1 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal adh_short_C2 PF13561.6 ACL95350.1 - 1.9e-60 204.3 8.9 2.3e-60 204.1 8.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ACL95350.1 - 1.5e-48 164.9 4.8 1.7e-48 164.7 4.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ACL95350.1 - 3.7e-07 30.2 3.0 6.3e-07 29.5 2.3 1.7 1 1 1 2 2 2 1 KR domain THF_DHG_CYH_C PF02882.19 ACL95350.1 - 0.0017 17.7 0.5 0.0034 16.7 0.1 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TonB_dep_Rec PF00593.24 ACL95351.3 - 6.4e-38 131.8 33.6 1.4e-37 130.7 25.7 2.9 2 1 0 2 2 2 2 TonB dependent receptor Plug PF07715.15 ACL95351.3 - 2.4e-15 57.0 0.2 8.1e-15 55.3 0.2 2.0 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain HTH_IclR PF09339.10 ACL95353.1 - 1.1e-11 44.4 0.0 2e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain Dimerisation2 PF16864.5 ACL95353.1 - 0.0027 17.6 0.0 0.0078 16.2 0.0 1.7 2 0 0 2 2 2 1 Dimerisation domain IclR PF01614.18 ACL95353.1 - 0.038 13.8 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial transcriptional regulator MarR_2 PF12802.7 ACL95353.1 - 0.097 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 MarR family AMP-binding PF00501.28 ACL95354.1 - 1.2e-79 267.9 0.0 1.4e-79 267.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ACL95354.1 - 9.8e-18 64.9 0.1 2.1e-17 63.9 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3HCDH PF00725.22 ACL95355.1 - 6.3e-13 49.2 0.0 7.4e-09 36.1 0.0 2.6 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_1 PF00378.20 ACL95355.1 - 8.5e-12 44.9 0.1 4.7e-11 42.5 0.1 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ACL95355.1 - 0.0085 15.6 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 ACL95356.1 - 2.6e-55 187.5 0.0 3e-55 187.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ACL95356.1 - 4.4e-30 105.3 0.0 1.5e-25 90.4 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase adh_short_C2 PF13561.6 ACL95357.1 - 5.7e-133 441.7 13.2 1e-66 224.9 3.7 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ACL95357.1 - 3.9e-107 356.0 7.1 3.8e-56 189.6 0.5 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 ACL95357.1 - 6.6e-19 68.5 9.4 3.6e-09 36.8 1.2 2.2 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 ACL95357.1 - 9.3e-08 31.8 5.6 0.0042 16.6 0.8 3.6 2 2 0 2 2 2 2 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 ACL95357.1 - 1.4e-05 25.1 4.7 0.011 15.7 0.8 3.4 2 1 1 3 3 3 2 Zinc-binding dehydrogenase TrkA_N PF02254.18 ACL95357.1 - 0.00011 22.4 2.1 0.032 14.5 0.5 2.5 2 0 0 2 2 2 2 TrkA-N domain Shikimate_DH PF01488.20 ACL95357.1 - 0.0012 18.9 0.1 2.3 8.3 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.17 ACL95357.1 - 0.0069 15.5 5.4 0.52 9.4 0.4 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain NAD_binding_10 PF13460.6 ACL95357.1 - 0.035 14.0 6.6 0.036 14.0 0.9 2.4 2 0 0 2 2 2 0 NAD(P)H-binding SnoaL_4 PF13577.6 ACL95358.1 - 3e-19 69.4 0.5 3.7e-19 69.1 0.5 1.1 1 0 0 1 1 1 1 SnoaL-like domain Ring_hydroxyl_B PF00866.18 ACL95358.1 - 0.00018 21.6 0.0 0.00028 21.0 0.0 1.2 1 0 0 1 1 1 1 Ring hydroxylating beta subunit Pyr_redox_2 PF07992.14 ACL95359.1 - 1.3e-15 57.4 0.0 1.3e-14 54.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ACL95359.1 - 2.2e-15 56.7 0.0 7.3e-15 55.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ACL95359.1 - 2.9e-13 49.1 0.0 4e-12 45.3 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ACL95359.1 - 1.3e-09 38.1 0.6 7.6e-09 35.7 0.5 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 ACL95359.1 - 2.2e-08 33.6 0.0 9.6e-07 28.2 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 ACL95359.1 - 5.3e-06 25.4 0.0 0.024 13.4 0.0 2.5 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 ACL95359.1 - 2.6e-05 24.0 1.7 0.0064 16.1 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ACL95359.1 - 0.00023 21.2 0.4 0.43 10.6 0.0 3.7 4 0 0 4 4 4 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 ACL95359.1 - 0.00091 18.4 0.3 0.0031 16.6 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 ACL95359.1 - 0.016 14.3 0.1 0.051 12.6 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.20 ACL95359.1 - 0.033 14.2 0.2 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Amino_oxidase PF01593.24 ACL95359.1 - 0.073 12.3 0.0 0.45 9.8 0.0 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase GIDA PF01134.22 ACL95359.1 - 0.092 11.8 0.4 4.7 6.2 0.0 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 ACL95359.1 - 0.12 11.7 0.5 0.2 11.0 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ACL95359.1 - 3.8 6.7 4.4 1.7 7.9 1.5 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.16 ACL95360.1 - 6.7e-43 147.0 37.7 6.7e-43 147.0 37.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.13 ACL95360.1 - 5.1e-07 28.5 5.0 5.1e-07 28.5 5.0 2.1 2 0 0 2 2 2 1 Transmembrane secretion effector Sugar_tr PF00083.24 ACL95360.1 - 2.6e-05 23.3 18.0 0.0013 17.7 17.9 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter AWPM-19 PF05512.11 ACL95360.1 - 0.077 13.2 3.8 0.38 10.9 3.8 2.2 1 0 0 1 1 1 0 AWPM-19-like family OATP PF03137.20 ACL95360.1 - 0.8 7.9 16.1 2.4 6.3 0.6 3.9 2 2 2 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family HTH_26 PF13443.6 ACL95361.1 - 0.011 16.1 0.0 0.14 12.6 0.0 2.0 1 1 1 2 2 2 0 Cro/C1-type HTH DNA-binding domain BMFP PF04380.13 ACL95361.1 - 0.11 13.0 0.9 8.6 6.9 0.3 2.1 2 0 0 2 2 2 0 Membrane fusogenic activity Lactamase_B_2 PF12706.7 ACL95362.1 - 1.6e-30 106.2 2.4 1.9e-30 105.9 2.4 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ACL95362.1 - 0.016 15.3 7.8 0.046 13.7 5.9 2.3 1 1 1 2 2 2 0 Metallo-beta-lactamase superfamily TatD_DNase PF01026.21 ACL95363.1 - 8.2e-73 244.9 0.0 9.8e-73 244.7 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_3 PF07969.11 ACL95363.1 - 0.0045 16.5 1.3 0.007 15.9 1.2 1.4 1 1 0 1 1 1 1 Amidohydrolase family Glyco_transf_28 PF03033.20 ACL95363.1 - 0.12 12.4 0.2 1.1 9.2 0.1 2.2 2 0 0 2 2 2 0 Glycosyltransferase family 28 N-terminal domain DNA_pol3_delta2 PF13177.6 ACL95364.1 - 3.7e-39 134.1 0.0 6.5e-39 133.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 ACL95364.1 - 0.00013 22.4 0.0 0.00029 21.3 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ACL95364.1 - 0.0048 17.3 2.8 0.025 14.9 2.7 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 ACL95364.1 - 0.0048 16.9 0.0 0.021 14.8 0.0 2.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 ACL95364.1 - 0.027 14.1 0.0 0.091 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 ACL95364.1 - 0.041 14.2 0.0 0.3 11.3 0.0 2.4 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ACL95364.1 - 0.046 14.1 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 ACL95364.1 - 0.078 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ACL95364.1 - 0.078 13.5 0.0 0.19 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 ACL95364.1 - 0.15 11.4 1.0 0.18 11.2 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Thymidylate_kin PF02223.17 ACL95365.1 - 6.6e-45 153.1 0.0 7.4e-45 152.9 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 ACL95365.1 - 1.5e-06 28.6 0.3 6.2e-06 26.5 0.2 1.9 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 ACL95365.1 - 0.0018 18.4 0.1 0.042 14.0 0.1 2.6 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 ACL95365.1 - 0.042 12.8 0.1 0.071 12.1 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 ACL95365.1 - 0.045 13.5 0.1 0.083 12.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 ACL95365.1 - 0.055 12.4 0.4 0.13 11.2 0.1 1.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Glyco_transf_4 PF13439.6 ACL95365.1 - 0.057 13.4 0.2 0.13 12.2 0.1 1.7 2 0 0 2 2 2 0 Glycosyltransferase Family 4 AAA_22 PF13401.6 ACL95365.1 - 0.06 13.6 0.0 0.099 12.9 0.0 1.6 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.6 ACL95365.1 - 0.067 13.6 0.0 0.66 10.4 0.0 2.3 3 0 0 3 3 3 0 AAA domain TIR_2 PF13676.6 ACL95365.1 - 0.085 13.5 0.0 0.2 12.3 0.0 1.6 1 1 1 2 2 2 0 TIR domain DPBB_1 PF03330.18 ACL95366.1 - 9.7e-24 83.5 0.0 2.6e-23 82.1 0.0 1.7 2 0 0 2 2 2 1 Lytic transglycolase SPOR PF05036.13 ACL95366.1 - 4.9e-14 52.5 1.3 1e-13 51.5 1.3 1.6 1 0 0 1 1 1 1 Sporulation related domain NikR_C PF08753.11 ACL95367.1 - 1.1e-19 70.3 0.1 1.6e-19 69.8 0.1 1.3 1 0 0 1 1 1 1 NikR C terminal nickel binding domain RHH_1 PF01402.21 ACL95367.1 - 1.3e-09 37.7 3.5 1.8e-09 37.2 0.6 2.2 2 0 0 2 2 2 1 Ribbon-helix-helix protein, copG family HicB_lk_antitox PF15919.5 ACL95367.1 - 0.00049 20.2 0.0 0.00073 19.7 0.0 1.3 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system RHH_5 PF07878.11 ACL95367.1 - 0.16 11.9 1.9 0.28 11.1 0.2 2.2 2 0 0 2 2 2 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 DUF1989 PF09347.10 ACL95368.1 - 7.5e-49 165.6 0.0 9.5e-49 165.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) DUF1989 PF09347.10 ACL95369.1 - 6.8e-61 204.8 0.1 8.1e-61 204.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) DUF2195 PF09961.9 ACL95369.1 - 0.028 14.4 0.1 0.041 13.8 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2195) CT_A_B PF02626.15 ACL95370.1 - 4.2e-91 305.2 0.0 7.9e-91 304.3 0.0 1.5 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 ACL95370.1 - 6.3e-63 212.1 0.0 1.2e-62 211.2 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ACL95370.1 - 8.6e-45 151.8 0.4 9.2e-44 148.5 0.2 2.5 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain CT_C_D PF02682.16 ACL95370.1 - 1.1e-43 149.4 0.0 2.2e-43 148.4 0.0 1.5 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_C PF02785.19 ACL95370.1 - 6.6e-31 106.6 0.0 1.3e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 ACL95370.1 - 4.7e-14 52.0 1.1 1.5e-13 50.4 1.2 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 ACL95370.1 - 1e-09 38.3 0.0 2e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 ACL95370.1 - 1.3e-05 24.9 0.7 0.0052 16.6 0.1 2.8 1 1 1 2 2 2 1 Biotin-lipoyl like ATP-grasp PF02222.22 ACL95370.1 - 7.3e-05 22.4 0.0 0.00036 20.2 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain HlyD_3 PF13437.6 ACL95370.1 - 0.00046 20.8 6.6 0.11 13.2 0.7 3.0 3 0 0 3 3 2 2 HlyD family secretion protein ATP-grasp_5 PF13549.6 ACL95370.1 - 0.0021 17.5 0.0 0.005 16.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 ACL95370.1 - 0.014 15.0 0.0 0.035 13.7 0.0 1.6 1 1 0 1 1 1 0 RimK-like ATP-grasp domain ATPgrasp_Ter PF15632.6 ACL95370.1 - 0.018 14.8 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon DUF2118 PF09891.9 ACL95370.1 - 0.037 14.0 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) RnfC_N PF13375.6 ACL95370.1 - 0.062 13.3 0.8 0.16 11.9 0.6 1.7 2 0 0 2 2 1 0 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 ACL95370.1 - 0.077 12.9 0.7 0.17 11.7 0.7 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein Amidase PF01425.21 ACL95371.1 - 2e-86 290.7 1.7 2.9e-86 290.2 1.7 1.2 1 0 0 1 1 1 1 Amidase ABC_tran PF00005.27 ACL95372.1 - 2.4e-31 109.1 0.0 3e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ACL95372.1 - 6.6e-09 36.0 0.0 4e-05 23.6 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ACL95372.1 - 0.0029 17.5 0.0 0.0045 16.9 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 ACL95372.1 - 0.0033 17.2 0.0 0.0063 16.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 ACL95372.1 - 0.0042 17.4 0.0 0.01 16.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ACL95372.1 - 0.0044 17.4 0.1 0.0081 16.6 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 ACL95372.1 - 0.007 16.4 0.0 0.015 15.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 ACL95372.1 - 0.018 15.2 0.0 0.028 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 ACL95372.1 - 0.059 13.6 0.0 0.17 12.1 0.0 1.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 ACL95372.1 - 0.074 13.5 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ACL95372.1 - 0.077 12.7 0.0 0.36 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 ACL95372.1 - 0.094 12.4 0.0 10 5.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain SMC_N PF02463.19 ACL95372.1 - 0.14 11.6 0.1 1.2 8.5 0.0 1.9 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 ACL95372.1 - 0.21 11.3 0.0 0.5 10.1 0.0 1.5 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 ACL95372.1 - 0.26 11.4 0.0 0.4 10.7 0.0 1.3 1 0 0 1 1 1 0 Dynamin family NB-ARC PF00931.22 ACL95372.1 - 0.26 10.4 0.0 0.97 8.6 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain BPD_transp_1 PF00528.22 ACL95373.1 - 1.3e-15 57.6 13.8 1.3e-15 57.6 13.8 1.5 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component NMT1_2 PF13379.6 ACL95374.1 - 4.3e-08 33.2 2.9 1.3e-07 31.6 2.9 1.7 1 1 0 1 1 1 1 NMT1-like family NMT1 PF09084.11 ACL95374.1 - 3.3e-07 30.5 0.8 5.9e-07 29.6 0.8 1.4 1 0 0 1 1 1 1 NMT1/THI5 like Lipoprotein_9 PF03180.14 ACL95374.1 - 0.0045 16.1 0.1 0.066 12.3 0.0 2.1 2 0 0 2 2 2 1 NLPA lipoprotein DUF2322 PF10084.9 ACL95375.1 - 0.12 12.5 0.0 0.12 12.5 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2322) Glyoxalase PF00903.25 ACL95376.1 - 7.6e-09 35.8 0.1 2.7e-08 34.0 0.1 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ACL95376.1 - 4.2e-06 27.5 0.0 5.8e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 ACL95376.1 - 0.0015 18.8 0.0 1.8 8.8 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 ACL95376.1 - 0.19 11.7 0.0 1.3 9.0 0.0 2.0 1 1 0 1 1 1 0 Glyoxalase-like domain ydhR PF08803.11 ACL95377.2 - 1.2e-08 34.7 0.0 1.5e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Putative mono-oxygenase ydhR HxlR PF01638.17 ACL95378.1 - 6.7e-31 106.0 0.1 8.6e-31 105.6 0.1 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix MarR PF01047.22 ACL95378.1 - 1.8e-05 24.6 0.1 4.4e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 MarR family PadR PF03551.14 ACL95378.1 - 0.00067 19.6 0.0 0.001 19.0 0.0 1.4 1 1 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_5 PF01022.20 ACL95378.1 - 0.0036 17.1 0.0 0.0068 16.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_45 PF14947.6 ACL95378.1 - 0.0055 16.7 0.0 0.0076 16.2 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix HTH_20 PF12840.7 ACL95378.1 - 0.033 14.2 0.0 0.48 10.5 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.7 ACL95378.1 - 0.043 13.7 0.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 MarR family B-block_TFIIIC PF04182.12 ACL95378.1 - 0.047 13.9 0.0 0.058 13.6 0.0 1.3 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC TrmB PF01978.19 ACL95378.1 - 0.09 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB MTS PF05175.14 ACL95379.1 - 9.4e-49 165.2 0.0 1.7e-47 161.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_11 PF08241.12 ACL95379.1 - 1.5e-09 38.4 0.0 0.00042 20.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 ACL95379.1 - 1.2e-07 32.4 0.0 0.00023 21.8 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain UPF0020 PF01170.18 ACL95379.1 - 2.2e-05 24.2 0.0 3.4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.12 ACL95379.1 - 0.0031 18.2 0.0 1 10.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Spermine_synth PF01564.17 ACL95379.1 - 0.072 12.5 0.0 0.12 11.8 0.0 1.4 1 1 0 1 1 1 0 Spermine/spermidine synthase domain Sterol_MT_C PF08498.10 ACL95379.1 - 0.13 12.6 0.2 1.9 8.9 0.0 2.3 2 0 0 2 2 2 0 Sterol methyltransferase C-terminal Cons_hypoth95 PF03602.15 ACL95379.1 - 0.21 11.2 0.0 0.36 10.4 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PseudoU_synth_2 PF00849.22 ACL95380.1 - 6.1e-19 68.7 0.0 2e-17 63.7 0.0 2.1 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 ACL95380.1 - 2.4e-08 33.6 0.3 4.4e-08 32.7 0.3 1.5 1 0 0 1 1 1 1 S4 domain Virul_fac_BrkB PF03631.15 ACL95381.1 - 5.4e-41 140.9 29.9 6.7e-41 140.6 29.9 1.1 1 0 0 1 1 1 1 Virulence factor BrkB IBV_3C PF03620.13 ACL95381.1 - 3.3 8.2 6.1 0.34 11.4 0.3 2.4 2 1 1 3 3 3 0 IBV 3C protein CoA_transf_3 PF02515.17 ACL95382.1 - 2.3e-85 287.0 0.0 2.9e-85 286.6 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III GGDEF PF00990.21 ACL95383.1 - 1.8e-09 37.5 0.0 6.3e-09 35.8 0.0 1.9 1 1 0 1 1 1 1 Diguanylate cyclase, GGDEF domain DSBA PF01323.20 ACL95384.1 - 5.2e-50 169.9 0.0 5.8e-50 169.8 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 ACL95384.1 - 0.017 15.3 0.0 0.074 13.2 0.0 2.0 1 1 0 1 1 1 0 Thioredoxin TRCF PF03461.15 ACL95385.1 - 3.8e-24 84.9 0.0 2.6e-23 82.2 0.0 2.5 3 0 0 3 3 3 1 TRCF domain CarD_CdnL_TRCF PF02559.16 ACL95385.1 - 1.3e-23 83.5 0.0 3.2e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 CarD-like/TRCF domain Helicase_C PF00271.31 ACL95385.1 - 3e-20 72.6 0.0 2.7e-18 66.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UvrB_inter PF17757.1 ACL95385.1 - 2e-19 69.6 0.0 4e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 UvrB interaction domain DEAD PF00270.29 ACL95385.1 - 1.4e-17 64.1 0.1 2.5e-17 63.2 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 ACL95385.1 - 3.6e-08 33.6 0.0 7.4e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 ACL95385.1 - 0.00019 20.3 0.0 0.00028 19.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SecA_DEAD PF07517.14 ACL95385.1 - 0.032 13.5 0.0 0.065 12.5 0.0 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain UB2H PF14814.6 ACL95385.1 - 0.038 14.0 0.0 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 Bifunctional transglycosylase second domain AAA_16 PF13191.6 ACL95385.1 - 0.099 13.0 0.7 0.5 10.7 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain AAA_25 PF13481.6 ACL95385.1 - 0.17 11.5 0.6 15 5.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Sdh5 PF03937.16 ACL95386.1 - 1.2e-24 86.1 0.0 1.4e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Methyltransf_11 PF08241.12 ACL95387.1 - 8.2e-21 74.5 0.0 1.3e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ACL95387.1 - 2.2e-17 63.5 0.0 3.3e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ACL95387.1 - 3.2e-15 56.4 0.0 4.5e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ACL95387.1 - 1.2e-13 51.2 0.0 1.9e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ACL95387.1 - 9.4e-10 39.1 0.0 1.4e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 ACL95387.1 - 1.4e-08 34.8 0.1 1.7e-07 31.3 0.1 2.0 1 1 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.18 ACL95387.1 - 6.9e-07 28.8 0.0 9.9e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 ACL95387.1 - 4.6e-06 26.4 0.0 6.6e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW TehB PF03848.14 ACL95387.1 - 0.00018 21.0 0.0 0.00047 19.6 0.0 1.6 1 1 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.14 ACL95387.1 - 0.07 12.7 0.2 1.2 8.7 0.2 2.1 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_9 PF08003.11 ACL95387.1 - 0.075 11.9 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) AdoMet_MTase PF07757.13 ACL95387.1 - 0.082 13.3 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase NNMT_PNMT_TEMT PF01234.17 ACL95387.1 - 0.14 11.4 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family CMAS PF02353.20 ACL95387.1 - 0.17 11.2 0.0 0.37 10.0 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_29 PF03141.16 ACL95387.1 - 0.19 10.2 0.0 0.48 8.9 0.0 1.6 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DEAD PF00270.29 ACL95388.1 - 4.2e-53 179.7 0.0 6e-53 179.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ACL95388.1 - 2.7e-30 104.9 0.0 3e-29 101.6 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ACL95388.1 - 2.5e-09 37.4 0.0 3.7e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 ACL95388.1 - 0.0077 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Helicase ERCC3_RAD25_C PF16203.5 ACL95388.1 - 0.032 13.4 0.0 0.048 12.9 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 ACL95388.1 - 0.14 12.4 0.5 1.4 9.2 0.3 2.6 1 1 1 2 2 2 0 AAA domain DUF563 PF04577.14 ACL95389.1 - 1e-37 130.3 0.0 1.4e-37 129.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Peptidase_M24 PF00557.24 ACL95389.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Metallopeptidase family M24 Prog_receptor PF02161.15 ACL95389.1 - 0.26 10.0 2.3 7.9 5.1 0.1 2.3 2 0 0 2 2 2 0 Progesterone receptor Aldedh PF00171.22 ACL95390.1 - 3.3e-89 299.5 0.0 3.9e-89 299.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family bact-PGI_C PF10432.9 ACL95390.1 - 0.12 12.4 0.0 0.33 11.0 0.0 1.7 2 0 0 2 2 2 0 Bacterial phospho-glucose isomerase C-terminal SIS domain GGDEF PF00990.21 ACL95391.1 - 3.6e-37 127.6 0.0 9.9e-37 126.2 0.0 1.7 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain Spc7 PF08317.11 ACL95391.1 - 0.0046 15.9 2.4 0.0082 15.1 2.4 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF1664 PF07889.12 ACL95391.1 - 0.008 16.2 1.6 0.032 14.3 1.4 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) CorA PF01544.18 ACL95391.1 - 0.016 14.5 1.7 0.026 13.8 1.7 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein BAR_2 PF10455.9 ACL95391.1 - 0.021 14.0 0.5 0.03 13.5 0.5 1.2 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Cluap1 PF10234.9 ACL95391.1 - 0.029 13.8 3.9 0.042 13.3 3.9 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF4515 PF14988.6 ACL95391.1 - 0.03 14.1 2.3 0.047 13.5 0.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4515) Transcrip_act PF04949.13 ACL95391.1 - 0.046 13.6 2.0 0.55 10.1 0.6 2.2 1 1 0 2 2 2 0 Transcriptional activator Fez1 PF06818.15 ACL95391.1 - 0.058 13.9 1.0 0.12 12.8 1.0 1.5 1 0 0 1 1 1 0 Fez1 Csm1_N PF18504.1 ACL95391.1 - 0.058 13.7 1.5 0.17 12.2 0.2 2.3 2 0 0 2 2 2 0 Csm1 N-terminal domain GAS PF13851.6 ACL95391.1 - 0.082 12.2 3.7 0.13 11.6 0.8 1.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Ribosomal_S15 PF00312.22 ACL95391.1 - 0.086 13.1 0.3 0.17 12.1 0.3 1.4 1 0 0 1 1 1 0 Ribosomal protein S15 ATG16 PF08614.11 ACL95391.1 - 0.087 13.0 5.0 0.17 12.1 5.0 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) PRKG1_interact PF15898.5 ACL95391.1 - 0.089 13.7 2.6 0.6 11.0 0.7 2.7 3 0 0 3 3 2 0 cGMP-dependent protein kinase interacting domain UPF0242 PF06785.11 ACL95391.1 - 0.12 12.5 2.1 0.26 11.4 2.1 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CHDCT2 PF08074.11 ACL95391.1 - 0.12 12.6 1.0 0.2 11.8 1.0 1.3 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain Gly_acyl_tr_N PF06021.11 ACL95391.1 - 0.13 12.4 0.0 0.21 11.6 0.0 1.4 1 1 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase DMPK_coil PF08826.10 ACL95391.1 - 0.13 12.4 3.3 0.3 11.2 0.5 2.5 2 0 0 2 2 2 0 DMPK coiled coil domain like IFT20 PF14931.6 ACL95391.1 - 0.14 12.3 1.4 0.29 11.3 1.4 1.5 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 PIN_9 PF18477.1 ACL95391.1 - 0.14 12.5 2.6 0.31 11.3 1.5 2.2 2 0 0 2 2 2 0 PIN like domain Prefoldin PF02996.17 ACL95391.1 - 0.25 11.3 2.1 3.4 7.6 0.2 2.3 2 0 0 2 2 2 0 Prefoldin subunit Cnn_1N PF07989.11 ACL95391.1 - 1.2 9.4 4.6 1.8 8.8 0.9 2.3 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 THOC7 PF05615.13 ACL95391.1 - 1.2 9.4 5.8 2.9 8.2 5.8 1.8 1 1 0 1 1 1 0 Tho complex subunit 7 FlgN PF05130.12 ACL95391.1 - 1.2 9.6 6.1 3.6 8.1 4.8 2.2 1 1 1 2 2 2 0 FlgN protein bZIP_2 PF07716.15 ACL95391.1 - 3 8.0 6.3 1.6 8.9 2.0 2.6 2 0 0 2 2 2 0 Basic region leucine zipper DUF1192 PF06698.11 ACL95391.1 - 3.5 7.8 7.4 0.71 10.0 0.7 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF1192) APG6_N PF17675.1 ACL95391.1 - 4.3 7.9 7.1 21 5.7 7.1 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region ECH_1 PF00378.20 ACL95392.1 - 1e-55 188.8 0.0 1.2e-55 188.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ACL95392.1 - 3.4e-25 89.2 0.1 1.1e-23 84.4 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase VPDSG-CTERM PF18205.1 ACL95392.1 - 0.065 13.1 0.9 1.1 9.1 0.1 3.0 2 0 0 2 2 2 0 VPDSG-CTERM motif ACT_3 PF10000.9 ACL95393.1 - 1.6e-17 63.2 0.0 3.3e-17 62.2 0.0 1.5 2 0 0 2 2 2 1 ACT domain ACT_7 PF13840.6 ACL95393.1 - 1.8e-09 37.2 0.1 3.2e-09 36.4 0.1 1.5 1 0 0 1 1 1 1 ACT domain Glyco_transf_9 PF01075.17 ACL95395.1 - 1.9e-14 53.6 0.0 3.1e-14 52.9 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) TetR_N PF00440.23 ACL95396.1 - 2.8e-15 55.8 0.6 2.8e-15 55.8 0.6 2.0 3 0 0 3 3 3 1 Bacterial regulatory proteins, tetR family AbiEi_4 PF13338.6 ACL95396.1 - 0.015 15.4 0.5 0.098 12.8 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin Acyltransferase PF01553.21 ACL95397.1 - 2.8e-16 59.4 0.0 4.1e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Fe-S_biosyn PF01521.20 ACL95399.1 - 2.5e-19 69.5 0.0 3e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis FeS_assembly_P PF01883.19 ACL95400.1 - 6.7e-20 71.1 0.0 8.8e-20 70.7 0.0 1.2 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein Aminotran_5 PF00266.19 ACL95401.1 - 9e-142 472.4 0.0 1e-141 472.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 ACL95401.1 - 2e-11 43.7 0.0 2.7e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 ACL95401.1 - 5.2e-08 31.8 0.1 3.4e-07 29.1 0.1 2.2 2 1 1 3 3 3 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 ACL95401.1 - 8.4e-07 28.6 0.6 1.6e-06 27.7 0.6 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 ACL95401.1 - 1.8e-05 24.2 0.3 2.3e-05 23.8 0.3 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase SelA PF03841.13 ACL95401.1 - 0.071 12.1 0.6 0.24 10.3 0.6 1.9 1 1 0 1 1 1 0 L-seryl-tRNA selenium transferase Complex1_51K PF01512.17 ACL95401.1 - 0.13 12.1 0.1 1.4 8.8 0.0 2.1 2 0 0 2 2 2 0 Respiratory-chain NADH dehydrogenase 51 Kd subunit UPF0051 PF01458.17 ACL95402.1 - 6.7e-54 182.9 0.2 8.1e-54 182.6 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) ABC_tran PF00005.27 ACL95403.1 - 2e-18 67.2 0.0 3e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ACL95403.1 - 1.2e-06 28.2 0.1 0.012 15.1 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ACL95403.1 - 0.0017 18.1 0.0 0.0036 17.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 ACL95403.1 - 0.0037 17.1 0.1 0.065 13.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ACL95403.1 - 0.006 16.5 0.0 0.0093 15.9 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 ACL95403.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ACL95403.1 - 0.012 16.1 0.0 0.015 15.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_27 PF13514.6 ACL95403.1 - 0.023 14.3 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 ACL95403.1 - 0.12 11.1 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ACL95403.1 - 0.15 12.3 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain UPF0051 PF01458.17 ACL95405.1 - 1.1e-66 224.7 0.0 1.3e-66 224.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) CHIPS PF11434.8 ACL95405.1 - 0.0031 17.3 0.0 0.0076 16.1 0.0 1.6 1 0 0 1 1 1 1 Chemotaxis-inhibiting protein CHIPS Aminotran_5 PF00266.19 ACL95406.1 - 3.7e-58 197.2 0.1 5e-58 196.8 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 ACL95406.1 - 6.5e-11 42.0 0.1 7.1e-08 32.0 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ACL95406.1 - 2.2e-08 33.8 2.9 2.8e-08 33.4 2.9 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.19 ACL95406.1 - 0.0032 16.2 0.1 0.0045 15.7 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Rrf2 PF02082.20 ACL95407.1 - 4.5e-26 91.0 0.2 6.9e-26 90.4 0.2 1.3 1 0 0 1 1 1 1 Transcriptional regulator MarR_2 PF12802.7 ACL95407.1 - 0.00017 21.4 0.4 0.0005 19.9 0.3 1.7 1 1 0 1 1 1 1 MarR family HrcA_DNA-bdg PF03444.15 ACL95407.1 - 0.0022 17.6 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding FeoC PF09012.10 ACL95407.1 - 0.11 12.6 0.1 0.32 11.1 0.0 1.8 2 0 0 2 2 2 0 FeoC like transcriptional regulator Peptidase_S15 PF02129.18 ACL95408.1 - 2.3e-09 37.3 0.0 2.7e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 ACL95408.1 - 1.1e-06 28.1 0.1 2.1e-05 23.9 0.1 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 ACL95408.1 - 2.3e-05 24.0 0.0 0.011 15.2 0.0 2.1 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 ACL95408.1 - 0.00015 21.5 0.0 0.00018 21.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ACL95408.1 - 0.0012 19.5 0.9 0.0021 18.7 0.7 1.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 ACL95408.1 - 0.067 12.7 0.0 0.088 12.3 0.0 1.1 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF829 PF05705.14 ACL95408.1 - 0.11 12.3 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) HNH PF01844.23 ACL95409.1 - 4.2e-08 33.2 7.0 6.8e-08 32.6 7.0 1.4 1 0 0 1 1 1 1 HNH endonuclease TackOD1 PF18551.1 ACL95409.1 - 0.032 13.9 0.7 0.042 13.5 0.7 1.1 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 HNH_2 PF13391.6 ACL95409.1 - 0.043 14.0 3.9 0.24 11.6 3.8 2.0 1 1 0 1 1 1 0 HNH endonuclease RecA_dep_nuc PF16786.5 ACL95409.1 - 0.075 13.2 0.2 0.12 12.6 0.2 1.4 1 0 0 1 1 1 0 Recombination enhancement, RecA-dependent nuclease HNH_4 PF13395.6 ACL95409.1 - 0.094 12.6 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 HNH endonuclease NRDD PF13597.6 ACL95409.1 - 0.29 9.9 0.5 0.38 9.5 0.5 1.1 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase AnmK PF03702.14 ACL95410.2 - 5e-75 252.9 0.0 6.9e-75 252.4 0.0 1.2 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase FGGY_C PF02782.16 ACL95410.2 - 5.5e-06 26.2 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Amdase PF17645.1 ACL95410.2 - 0.068 12.8 0.0 0.29 10.7 0.0 1.9 2 0 0 2 2 2 0 Arylmalonate decarboxylase tRNA-synt_1b PF00579.25 ACL95411.2 - 1.5e-72 244.4 0.0 1.9e-72 244.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 ACL95411.2 - 0.00018 21.1 0.0 0.0004 20.0 0.0 1.6 1 0 0 1 1 1 1 S4 domain TyrRSs_C PF16714.5 ACL95411.2 - 0.14 12.0 0.1 0.29 11.0 0.1 1.5 1 0 0 1 1 1 0 Tyrosyl-tRNA synthetase C-terminal domain AhpC-TSA PF00578.21 ACL95412.1 - 4.5e-36 123.5 0.0 5.2e-36 123.3 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ACL95412.1 - 5.3e-20 71.6 0.0 5.7e-20 71.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin DUF899 PF05988.12 ACL95412.1 - 0.0012 18.4 0.0 0.0014 18.2 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) AhpC-TSA_2 PF13911.6 ACL95412.1 - 0.0079 16.3 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Peptidase_M23 PF01551.22 ACL95413.1 - 5.4e-30 103.5 0.9 1e-29 102.6 0.9 1.5 1 0 0 1 1 1 1 Peptidase family M23 Bactofilin PF04519.13 ACL95414.1 - 2.1e-23 82.5 4.5 2.7e-23 82.1 4.5 1.1 1 0 0 1 1 1 1 Polymer-forming cytoskeletal PCRF PF03462.18 ACL95415.1 - 3.3e-55 187.0 0.3 3.3e-55 187.0 0.3 1.7 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 ACL95415.1 - 5.2e-42 142.5 0.2 5.2e-42 142.5 0.2 2.1 2 0 0 2 2 2 1 RF-1 domain YqaJ PF09588.10 ACL95415.1 - 0.089 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 YqaJ-like viral recombinase domain DHR10 PF18595.1 ACL95415.1 - 0.12 12.5 13.3 0.056 13.5 4.8 2.5 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Transgly PF00912.22 ACL95416.1 - 2.4e-60 203.0 0.0 3.6e-60 202.5 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase Transpeptidase PF00905.22 ACL95416.1 - 2.6e-35 122.1 0.0 1.1e-33 116.8 0.0 2.3 1 1 0 1 1 1 1 Penicillin binding protein transpeptidase domain PCB_OB PF17092.5 ACL95416.1 - 3e-10 40.8 1.6 7.3e-10 39.6 1.6 1.7 1 0 0 1 1 1 1 Penicillin-binding protein OB-like domain Amidase_3 PF01520.18 ACL95417.3 - 1.1e-47 162.4 0.0 1.3e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase AMIN PF11741.8 ACL95417.3 - 0.014 15.5 0.1 0.7 10.1 0.0 2.9 2 1 2 4 4 4 0 AMIN domain RNase_E_G PF10150.9 ACL95419.1 - 4.7e-93 311.5 0.2 8.5e-93 310.7 0.2 1.4 1 0 0 1 1 1 1 Ribonuclease E/G family S1 PF00575.23 ACL95419.1 - 0.00022 21.5 1.3 0.0068 16.7 1.3 2.9 1 1 0 1 1 1 1 S1 RNA binding domain DnaJ_CXXCXGXG PF00684.19 ACL95419.1 - 0.043 14.2 0.0 0.088 13.2 0.0 1.4 1 0 0 1 1 1 0 DnaJ central domain Peptidase_M48 PF01435.18 ACL95420.1 - 5.1e-42 143.9 0.0 7.7e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 TPR_17 PF13431.6 ACL95420.1 - 3.7e-11 42.6 0.7 0.0016 18.7 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 ACL95420.1 - 5.7e-11 42.8 4.7 9.6e-05 22.8 0.1 4.4 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 ACL95420.1 - 1.3e-09 38.1 11.9 1.3e-05 25.6 0.1 5.1 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 ACL95420.1 - 2.9e-08 34.2 0.4 2.9e-08 34.2 0.4 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 ACL95420.1 - 2.4e-05 24.1 4.3 0.37 11.0 0.1 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 ACL95420.1 - 0.00035 20.2 0.7 4.5 7.1 0.0 4.3 4 1 1 5 5 5 2 TPR repeat Fis1_TPR_C PF14853.6 ACL95420.1 - 0.0005 20.1 0.9 0.015 15.4 0.1 3.1 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 ACL95420.1 - 0.00077 19.6 7.2 0.14 12.3 0.0 3.6 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 ACL95420.1 - 0.0026 17.5 1.5 15 5.6 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 ACL95420.1 - 0.0035 17.4 0.8 11 6.5 0.0 4.7 4 1 1 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ACL95420.1 - 0.0036 17.5 0.1 0.22 11.8 0.0 2.8 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 ACL95420.1 - 0.0085 15.9 2.5 8.4 6.4 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 ACL95420.1 - 0.03 14.9 0.1 0.03 14.9 0.1 3.5 3 1 0 3 3 2 0 Tetratricopeptide repeat DSBA PF01323.20 ACL95421.1 - 6.1e-25 88.1 4.5 1e-24 87.4 1.1 2.5 2 1 0 2 2 2 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 ACL95421.1 - 1.6e-17 64.2 0.0 5.8e-17 62.3 0.0 1.7 1 1 1 2 2 2 1 Thioredoxin ScsC_N PF18312.1 ACL95421.1 - 4.9e-15 55.0 0.9 1.6e-14 53.4 0.9 1.9 1 0 0 1 1 1 1 Copper resistance protein ScsC N-terminal domain Thioredoxin_2 PF13098.6 ACL95421.1 - 3.4e-05 24.3 0.0 0.00024 21.5 0.0 2.1 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin PF00085.20 ACL95421.1 - 0.058 13.4 0.0 0.18 11.8 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin ThiG PF05690.14 ACL95422.1 - 2.6e-110 367.6 0.9 2.9e-110 367.4 0.9 1.0 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 ACL95422.1 - 0.0025 17.3 0.2 0.009 15.5 0.1 1.8 2 0 0 2 2 2 1 Histidine biosynthesis protein Hydrolase PF00702.26 ACL95422.1 - 0.011 16.1 0.1 0.025 14.9 0.0 1.6 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Carb_kinase PF01256.17 ACL95422.1 - 0.05 13.1 0.2 6.3 6.2 0.1 2.2 2 0 0 2 2 2 0 Carbohydrate kinase Lys-AminoMut_A PF09043.11 ACL95422.1 - 0.085 11.3 0.1 0.13 10.7 0.1 1.2 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit ThiS PF02597.20 ACL95423.1 - 6.1e-16 58.8 0.2 6.6e-16 58.7 0.2 1.0 1 0 0 1 1 1 1 ThiS family HSDR_N_2 PF13588.6 ACL95423.1 - 0.14 12.2 0.0 0.17 11.9 0.0 1.1 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) DHquinase_II PF01220.19 ACL95424.1 - 3.1e-55 185.6 0.0 3.5e-55 185.5 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Biotin_lipoyl PF00364.22 ACL95425.1 - 1.3e-22 79.4 0.9 2.3e-22 78.6 0.9 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 ACL95425.1 - 5.1e-08 32.6 0.5 0.0013 18.6 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like RnfC_N PF13375.6 ACL95425.1 - 0.00043 20.2 0.1 0.00084 19.3 0.1 1.5 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 ACL95425.1 - 0.00096 19.0 0.3 0.0086 16.0 0.1 2.1 2 0 0 2 2 2 1 Glycine cleavage H-protein NQRA PF05896.11 ACL95425.1 - 0.037 13.5 0.1 0.048 13.1 0.1 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) DUF2057 PF09829.9 ACL95425.1 - 0.065 13.4 0.1 0.089 12.9 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) HlyD_3 PF13437.6 ACL95425.1 - 0.11 13.2 1.7 2.8 8.7 0.1 2.8 2 1 1 3 3 3 0 HlyD family secretion protein Peptidase_M23 PF01551.22 ACL95425.1 - 0.24 11.6 0.5 12 6.2 0.1 2.6 1 1 1 2 2 2 0 Peptidase family M23 CPSase_L_D2 PF02786.17 ACL95426.1 - 3.4e-83 278.3 0.1 4.8e-83 277.8 0.1 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ACL95426.1 - 9.3e-46 154.9 0.1 2.2e-45 153.7 0.1 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ACL95426.1 - 1.1e-35 122.0 0.0 2.2e-35 121.0 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 ACL95426.1 - 1.1e-10 41.4 0.0 2.9e-10 40.0 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 ACL95426.1 - 1.1e-09 38.2 0.1 2.2e-09 37.1 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 ACL95426.1 - 0.00017 21.7 0.0 0.00048 20.2 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.6 ACL95426.1 - 0.00075 19.0 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 ACL95426.1 - 0.016 15.0 0.1 0.022 14.6 0.1 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 ACL95426.1 - 0.025 14.2 0.0 1.7 8.2 0.0 2.1 2 0 0 2 2 2 0 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.6 ACL95426.1 - 0.034 13.4 0.0 0.076 12.3 0.0 1.5 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp ATP-grasp_4 PF13535.6 ACL95426.1 - 0.098 12.2 0.0 0.72 9.4 0.0 2.4 3 1 0 3 3 3 0 ATP-grasp domain Leu_Phe_trans PF03588.14 ACL95427.1 - 3.1e-64 215.5 0.0 3.8e-64 215.3 0.0 1.1 1 0 0 1 1 1 1 Leucyl/phenylalanyl-tRNA protein transferase Acetyltransf_6 PF13480.7 ACL95427.1 - 0.00021 21.5 0.4 0.00044 20.4 0.2 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2155 PF09923.9 ACL95428.2 - 2.3e-29 101.5 0.0 3.3e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2155) DUF3729 PF12526.8 ACL95428.2 - 3.9 9.1 22.8 1.7 10.2 17.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3729) NDUFA12 PF05071.16 ACL95429.1 - 1.5e-24 86.7 2.1 1.7e-24 86.4 2.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 zf-RRN7 PF11781.8 ACL95431.1 - 0.0059 16.3 0.5 0.01 15.5 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Ribonuc_red_lgC PF02867.15 ACL95431.1 - 0.047 12.2 0.0 0.31 9.5 0.0 1.9 2 0 0 2 2 2 0 Ribonucleotide reductase, barrel domain RNA_POL_M_15KD PF02150.16 ACL95431.1 - 0.051 13.5 0.5 0.09 12.7 0.5 1.3 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit TF_Zn_Ribbon PF08271.12 ACL95431.1 - 0.12 12.0 1.4 0.27 10.8 1.4 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding Pentapeptide PF00805.22 ACL95432.1 - 9.6e-26 89.0 23.4 5.7e-10 38.7 1.4 3.5 1 1 3 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 ACL95432.1 - 3.9e-15 55.8 0.0 6e-08 32.7 0.0 2.4 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 ACL95432.1 - 3.7e-11 43.0 2.8 8.1e-07 29.1 3.8 2.7 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 ACL95433.1 - 2.3e-50 167.7 63.9 2.4e-11 43.1 3.7 5.9 2 2 4 7 7 7 7 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 ACL95433.1 - 6e-44 148.1 10.8 3.2e-12 46.4 0.5 3.6 1 1 4 5 5 5 5 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 ACL95433.1 - 1.4e-25 89.2 22.6 3.6e-06 27.0 2.3 5.2 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) Peptidase_A4 PF01828.17 ACL95433.1 - 0.03 13.8 0.4 2.3 7.7 0.2 2.2 1 1 1 2 2 2 0 Peptidase A4 family tRNA-synt_2 PF00152.20 ACL95434.1 - 1.2e-97 326.8 0.0 1.4e-97 326.6 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ACL95434.1 - 3.9e-14 52.4 0.0 6.4e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain GAD PF02938.14 ACL95434.1 - 1.4e-05 25.2 0.0 2.8e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 GAD domain TIM PF00121.18 ACL95435.1 - 1.2e-79 267.2 0.0 1.3e-79 267.0 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Rotamase_2 PF13145.6 ACL95436.1 - 8.1e-36 123.5 30.0 1.6e-20 74.1 0.8 5.6 5 0 0 5 5 5 4 PPIC-type PPIASE domain SurA_N_3 PF13624.6 ACL95436.1 - 2.8e-34 118.3 0.2 7.7e-34 116.8 0.0 1.9 2 0 0 2 2 2 1 SurA N-terminal domain SurA_N_2 PF13623.6 ACL95436.1 - 4.3e-21 75.3 0.0 1.1e-20 74.0 0.0 1.7 1 0 0 1 1 1 1 SurA N-terminal domain Rotamase PF00639.21 ACL95436.1 - 3.9e-07 30.9 6.4 0.033 15.2 0.0 3.8 3 0 0 3 3 3 2 PPIC-type PPIASE domain Rotamase_3 PF13616.6 ACL95436.1 - 0.00027 21.5 1.8 0.13 12.8 0.5 3.2 2 1 0 2 2 2 2 PPIC-type PPIASE domain HsbA PF12296.8 ACL95436.1 - 0.019 15.4 1.8 0.019 15.4 1.8 3.0 3 1 0 4 4 4 0 Hydrophobic surface binding protein A Flu_NS1 PF00600.19 ACL95436.1 - 0.037 13.6 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 Influenza non-structural protein (NS1) DUF5403 PF17395.2 ACL95436.1 - 6.3 7.2 11.0 4.2 7.7 0.2 3.8 4 0 0 4 4 4 0 Family of unknown function (DUF5403) Chorismate_bind PF00425.18 ACL95437.1 - 3.4e-97 325.1 0.0 1.9e-96 322.6 0.0 1.9 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 ACL95437.1 - 3.2e-27 95.5 0.0 4.3e-26 91.8 0.0 2.5 3 0 0 3 3 3 1 Anthranilate synthase component I, N terminal region DUF3392 PF11872.8 ACL95438.1 - 0.088 13.1 0.1 0.1 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3392) GATase PF00117.28 ACL95439.1 - 5e-56 189.5 0.0 5.5e-56 189.3 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ACL95439.1 - 1e-13 51.6 0.1 2e-13 50.6 0.1 1.5 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.19 ACL95439.1 - 0.0061 16.4 0.0 0.012 15.4 0.0 1.4 1 1 0 1 1 1 1 SNO glutamine amidotransferase family Glycos_transf_3 PF00591.21 ACL95440.1 - 1.1e-95 320.0 0.8 1.4e-95 319.7 0.8 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 ACL95440.1 - 6.5e-18 64.3 1.7 1.1e-17 63.6 0.2 2.1 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain HTH_31 PF13560.6 ACL95440.1 - 0.016 15.5 5.0 1.7 9.1 0.0 4.1 3 1 1 4 4 4 0 Helix-turn-helix domain IGPS PF00218.21 ACL95441.1 - 2.1e-93 312.2 0.1 2.4e-93 312.0 0.1 1.0 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase CP_ATPgrasp_2 PF14403.6 ACL95441.1 - 0.008 15.1 0.1 0.012 14.6 0.1 1.2 1 0 0 1 1 1 1 Circularly permuted ATP-grasp type 2 FMN_dh PF01070.18 ACL95441.1 - 0.031 13.3 1.9 0.062 12.3 0.5 2.1 1 1 0 2 2 2 0 FMN-dependent dehydrogenase Lactamase_B_5 PF14597.6 ACL95441.1 - 0.073 12.6 0.3 0.26 10.8 0.1 1.9 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Acyltransferase PF01553.21 ACL95442.1 - 1.5e-12 47.3 0.0 2.1e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Methyltransf_11 PF08241.12 ACL95443.1 - 1.6e-21 76.7 0.0 9.8e-21 74.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ACL95443.1 - 2.8e-17 63.2 0.0 2.4e-16 60.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ACL95443.1 - 1.3e-11 44.5 0.0 2.2e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ACL95443.1 - 1.6e-11 44.8 0.0 3.2e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ACL95443.1 - 5e-07 29.7 0.0 7.4e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ACL95443.1 - 1.7e-05 24.3 0.0 0.00016 21.1 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 ACL95443.1 - 8e-05 22.3 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.12 ACL95443.1 - 0.0027 17.2 0.0 0.008 15.7 0.0 1.7 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase PCMT PF01135.19 ACL95443.1 - 0.0052 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_33 PF10017.9 ACL95443.1 - 0.01 15.0 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent FmrO PF07091.11 ACL95443.1 - 0.022 14.3 0.0 0.055 13.0 0.0 1.6 1 1 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_29 PF03141.16 ACL95443.1 - 0.084 11.4 0.0 0.64 8.5 0.0 2.0 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase CMAS PF02353.20 ACL95443.1 - 0.096 12.0 0.0 0.62 9.3 0.0 1.9 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.15 ACL95443.1 - 0.12 12.2 0.0 0.92 9.3 0.0 2.0 2 0 0 2 2 2 0 Hypothetical methyltransferase LexA_DNA_bind PF01726.16 ACL95444.2 - 7.9e-16 57.6 1.1 7.6e-15 54.4 0.2 2.2 2 0 0 2 2 2 1 LexA DNA binding domain Peptidase_S24 PF00717.23 ACL95444.2 - 2.3e-14 53.1 0.0 3.7e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like MarR PF01047.22 ACL95444.2 - 0.0013 18.6 0.1 0.0042 17.0 0.1 1.9 1 1 0 1 1 1 1 MarR family MarR_2 PF12802.7 ACL95444.2 - 0.0047 16.8 0.1 0.011 15.5 0.1 1.7 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 ACL95444.2 - 0.013 15.3 0.0 0.037 13.8 0.0 1.8 2 0 0 2 2 2 0 IclR helix-turn-helix domain PEP_mutase PF13714.6 ACL95445.1 - 1.9e-67 227.2 2.0 2.1e-67 227.0 2.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 ACL95445.1 - 0.00076 18.1 0.0 0.0012 17.4 0.0 1.2 1 0 0 1 1 1 1 Isocitrate lyase family Competence PF03772.16 ACL95446.1 - 2.6e-63 213.8 30.0 2.6e-63 213.8 30.0 1.9 2 0 0 2 2 2 1 Competence protein DUF4131 PF13567.6 ACL95446.1 - 2.7e-12 46.7 0.5 2.7e-12 46.7 0.5 4.2 3 1 0 3 3 3 1 Domain of unknown function (DUF4131) DUF4175 PF13779.6 ACL95446.1 - 0.61 7.9 3.1 1.4 6.8 3.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) tRNA-synt_1c PF00749.21 ACL95447.1 - 2.4e-88 296.1 0.0 4.4e-88 295.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Citrate_synt PF00285.21 ACL95448.1 - 3.8e-133 444.0 0.0 4.4e-133 443.8 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Bac_export_2 PF01312.19 ACL95449.1 - 1.4e-21 77.0 0.3 1.6e-21 76.9 0.3 1.0 1 0 0 1 1 1 1 FlhB HrpN YscU SpaS Family Flg_hook PF02120.16 ACL95450.1 - 3.7e-12 46.0 0.3 2.6e-11 43.3 0.0 2.7 2 1 1 3 3 3 1 Flagellar hook-length control protein FliK LpxB PF02684.15 ACL95451.1 - 1e-79 268.1 0.0 1.2e-79 267.9 0.0 1.0 1 0 0 1 1 1 1 Lipid-A-disaccharide synthetase LpxI_C PF06230.11 ACL95452.1 - 7e-46 155.4 1.2 8.5e-46 155.1 0.6 1.5 2 0 0 2 2 2 1 LpxI C-terminal domain LpxI_N PF17930.1 ACL95452.1 - 2.3e-36 124.5 0.1 6.7e-36 123.0 0.0 1.7 2 0 0 2 2 2 1 LpxI N-terminal domain Acetyltransf_11 PF13720.6 ACL95453.1 - 3.7e-24 85.0 0.0 5.4e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Hexapep PF00132.24 ACL95453.1 - 1.7e-15 56.0 10.5 0.003 17.2 0.7 6.4 4 2 2 6 6 6 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 ACL95453.1 - 0.93 9.3 6.2 5.3 6.9 0.1 4.1 4 1 1 5 5 5 0 Hexapeptide repeat of succinyl-transferase FabA PF07977.13 ACL95454.1 - 2.7e-35 121.0 0.0 3.2e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 FabA-like domain 4HBT PF03061.22 ACL95454.1 - 6.7e-07 29.6 0.1 1.5e-06 28.4 0.1 1.6 1 1 1 2 2 2 1 Thioesterase superfamily MaoC_dehydratas PF01575.19 ACL95454.1 - 7.2e-05 22.4 0.3 0.00021 20.9 0.2 1.8 1 1 1 2 2 2 1 MaoC like domain AfsA PF03756.13 ACL95454.1 - 0.029 14.4 0.0 0.04 13.9 0.0 1.4 1 1 0 1 1 1 0 A-factor biosynthesis hotdog domain 4HBT_2 PF13279.6 ACL95454.1 - 0.17 12.4 0.0 0.17 12.4 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily Hexapep PF00132.24 ACL95455.1 - 2.7e-30 103.0 31.7 1.5e-10 40.3 7.8 6.4 4 1 2 6 6 6 6 Bacterial transferase hexapeptide (six repeats) LpxD PF04613.14 ACL95455.1 - 3.9e-15 55.4 0.7 9.5e-15 54.1 0.7 1.7 1 0 0 1 1 1 1 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD Hexapep_2 PF14602.6 ACL95455.1 - 4.4e-12 45.5 36.2 1.5e-05 24.6 6.4 5.6 3 2 2 5 5 5 4 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 ACL95455.1 - 0.26 9.3 1.9 4.1 5.4 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4954) OmpH PF03938.14 ACL95456.1 - 2e-21 76.8 6.8 2.5e-21 76.5 6.8 1.1 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) JIP_LZII PF16471.5 ACL95456.1 - 0.11 12.7 3.3 0.27 11.4 0.6 2.6 2 1 2 4 4 4 0 JNK-interacting protein leucine zipper II GCN5L1 PF06320.13 ACL95456.1 - 0.73 10.0 11.1 16 5.7 3.8 3.3 1 1 2 3 3 3 0 GCN5-like protein 1 (GCN5L1) DUF3568 PF12092.8 ACL95456.1 - 1 9.5 0.0 1 9.5 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3568) Bac_surface_Ag PF01103.23 ACL95457.1 - 1.1e-90 304.4 7.1 1.5e-90 304.0 7.1 1.2 1 0 0 1 1 1 1 Surface antigen POTRA PF07244.15 ACL95457.1 - 5.8e-65 215.9 16.0 2.4e-16 60.1 0.4 5.4 5 0 0 5 5 5 5 Surface antigen variable number repeat POTRA_1 PF08478.10 ACL95457.1 - 3e-05 24.2 1.9 0.22 11.9 0.1 3.8 4 0 0 4 4 4 2 POTRA domain, FtsQ-type POTRA_2 PF08479.11 ACL95457.1 - 0.092 12.6 0.4 7.6 6.5 0.0 3.5 4 0 0 4 4 4 0 POTRA domain, ShlB-type Peptidase_M50 PF02163.22 ACL95458.3 - 8.5e-74 248.0 0.1 1.1e-73 247.7 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M50 PDZ_2 PF13180.6 ACL95458.3 - 3.3e-11 43.3 0.0 6.5e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 ACL95458.3 - 4.1e-10 39.3 0.1 8e-10 38.4 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 ACL95458.3 - 1.9e-05 24.9 0.0 4e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain L_HMGIC_fpl PF10242.9 ACL95458.3 - 0.019 15.2 2.4 0.15 12.3 0.0 2.6 3 0 0 3 3 3 0 Lipoma HMGIC fusion partner-like protein DXP_redisom_C PF08436.12 ACL95459.1 - 4.7e-40 135.6 0.1 8.8e-40 134.8 0.1 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain DXP_reductoisom PF02670.16 ACL95459.1 - 1.5e-37 129.2 1.7 2.6e-37 128.4 1.7 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXPR_C PF13288.6 ACL95459.1 - 3.6e-36 123.9 0.0 5.7e-36 123.3 0.0 1.3 1 0 0 1 1 1 1 DXP reductoisomerase C-terminal domain CTP_transf_1 PF01148.20 ACL95460.1 - 6.8e-65 219.5 19.4 8e-65 219.2 19.4 1.0 1 0 0 1 1 1 1 Cytidylyltransferase family CarS-like PF01864.17 ACL95460.1 - 0.00064 19.8 7.2 0.00075 19.5 1.3 2.4 2 0 0 2 2 2 2 CDP-archaeol synthase Prenyltransf PF01255.19 ACL95461.1 - 6.5e-77 258.0 0.0 7.5e-77 257.8 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase RRF PF01765.19 ACL95462.1 - 1.2e-61 207.4 1.4 1.4e-61 207.2 1.4 1.0 1 0 0 1 1 1 1 Ribosome recycling factor 14-3-3 PF00244.20 ACL95462.1 - 0.004 16.7 2.1 0.0067 16.0 2.1 1.3 1 0 0 1 1 1 1 14-3-3 protein DNTTIP1_dimer PF18192.1 ACL95462.1 - 0.13 12.6 0.8 0.74 10.2 0.7 2.1 1 1 1 2 2 2 0 DNTTIP1 dimerisation domain ATP-synt_B PF00430.18 ACL95462.1 - 4.5 7.4 11.9 9.1 6.4 11.9 1.4 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) AA_kinase PF00696.28 ACL95463.1 - 2.5e-31 109.1 0.2 2.8e-31 108.9 0.2 1.0 1 0 0 1 1 1 1 Amino acid kinase family DHFR_1 PF00186.19 ACL95463.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Dihydrofolate reductase EF_TS PF00889.19 ACL95464.1 - 4.7e-67 225.6 0.1 6.4e-67 225.2 0.1 1.2 1 0 0 1 1 1 1 Elongation factor TS Ribosomal_S2 PF00318.20 ACL95465.1 - 2.9e-90 301.2 0.0 3.3e-90 301.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S2 HAD PF12710.7 ACL95466.1 - 1.9e-30 106.7 0.2 2.2e-30 106.5 0.2 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ACL95466.1 - 0.00013 22.3 0.2 0.0081 16.5 0.2 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ACL95466.1 - 0.2 11.4 0.0 1.1 8.9 0.1 2.1 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Methyltransf_23 PF13489.6 ACL95467.1 - 1.3e-13 51.2 0.0 1.6e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ACL95467.1 - 1.8e-10 41.4 0.0 4.8e-10 40.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ACL95467.1 - 1.8e-10 41.3 0.0 3e-09 37.4 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ACL95467.1 - 3.1e-07 31.0 0.0 6.8e-07 30.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain TehB PF03848.14 ACL95467.1 - 0.00014 21.4 0.0 0.00019 20.9 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_31 PF13847.6 ACL95467.1 - 0.00067 19.5 0.0 0.0014 18.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 ACL95467.1 - 0.072 12.6 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase MTS PF05175.14 ACL95467.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DNA_pol3_alpha PF07733.12 ACL95468.1 - 1.4e-100 336.2 0.0 2.3e-100 335.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha NTPase domain DNA_pol3_finger PF17657.1 ACL95468.1 - 2.2e-61 206.1 0.0 3.6e-61 205.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha subunit finger domain PHP PF02811.19 ACL95468.1 - 1.3e-31 110.1 0.0 2.4e-31 109.3 0.0 1.5 1 0 0 1 1 1 1 PHP domain HHH_6 PF14579.6 ACL95468.1 - 9.9e-29 99.5 1.1 1.6e-28 98.8 0.1 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif tRNA_anti-codon PF01336.25 ACL95468.1 - 2.4e-06 27.4 0.0 5.8e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain IU_nuc_hydro PF01156.19 ACL95470.1 - 5.1e-70 236.5 0.1 5.7e-70 236.3 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase ABC_tran PF00005.27 ACL95471.1 - 5.1e-31 108.0 0.0 6.5e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ACL95471.1 - 4.5e-08 33.3 0.2 0.00084 19.2 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ACL95471.1 - 4.7e-05 22.9 0.0 0.067 12.6 0.0 2.0 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ACL95471.1 - 0.00059 20.3 0.5 0.00096 19.6 0.5 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 ACL95471.1 - 0.004 16.9 0.0 0.007 16.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain cobW PF02492.19 ACL95471.1 - 0.0051 16.4 0.3 0.077 12.6 0.3 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 ACL95471.1 - 0.03 13.9 0.1 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 ACL95471.1 - 0.065 13.5 0.2 2.4 8.4 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ACL95471.1 - 0.071 13.3 0.7 0.31 11.2 0.7 2.0 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 ACL95471.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase SbcCD_C PF13558.6 ACL95471.1 - 0.16 12.2 0.0 2.4 8.5 0.0 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit MacB_PCD PF12704.7 ACL95472.1 - 1.1e-16 61.7 3.1 1.1e-16 61.7 3.1 1.8 2 0 0 2 2 2 1 MacB-like periplasmic core domain FtsX PF02687.21 ACL95472.1 - 3.5e-09 37.0 1.5 3.5e-09 37.0 1.5 3.1 3 0 0 3 3 3 1 FtsX-like permease family UBM PF14377.6 ACL95472.1 - 0.18 11.3 0.2 0.37 10.3 0.2 1.6 1 0 0 1 1 1 0 Ubiquitin binding region tRNA-synt_2b PF00587.25 ACL95473.1 - 6.2e-36 124.0 0.0 8.7e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 ACL95473.1 - 2.4e-15 56.4 0.0 5.7e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain DUF1467 PF07330.12 ACL95475.1 - 9.7e-31 105.6 1.5 1.1e-30 105.4 1.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1467) Glyoxalase_4 PF13669.6 ACL95476.1 - 1.2e-18 67.4 0.0 1.6e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 ACL95476.1 - 1.1e-10 41.7 0.0 1.3e-10 41.5 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ACL95476.1 - 3.2e-06 27.9 0.0 4.1e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 ACL95476.1 - 8.9e-05 22.7 0.0 0.0001 22.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Lactamase_B_2 PF12706.7 ACL95477.1 - 3.1e-10 39.9 0.1 5.5e-10 39.1 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ACL95477.1 - 2.2e-09 37.6 2.1 5.3e-09 36.4 2.1 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 ACL95477.1 - 4.8e-07 29.6 0.3 1.7e-06 27.9 0.1 1.9 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Pan_kinase PF03309.14 ACL95478.1 - 1.2e-68 231.0 0.3 1.5e-68 230.8 0.3 1.1 1 0 0 1 1 1 1 Type III pantothenate kinase DUF3168 PF11367.8 ACL95478.1 - 0.028 14.6 0.1 0.42 10.8 0.0 2.6 3 1 1 4 4 4 0 Protein of unknown function (DUF3168) BPL_C PF02237.17 ACL95479.1 - 5.8e-12 45.3 0.1 1.1e-11 44.5 0.1 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain BPL_LplA_LipB PF03099.19 ACL95479.1 - 4.6e-11 42.7 0.0 6.6e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_LplA_LipB_2 PF16917.5 ACL95479.1 - 1.1e-08 34.8 0.3 1.8e-08 34.1 0.3 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Proton_antipo_M PF00361.20 ACL95480.1 - 1.1e-74 251.3 16.6 1.1e-74 251.3 16.6 2.1 2 0 0 2 2 2 1 Proton-conducting membrane transporter Phage_holin_Dp1 PF16938.5 ACL95480.1 - 1.6 9.0 0.0 1.6 9.0 0.0 3.4 3 0 0 3 3 3 0 Putative phage holin Dp-1 Proton_antipo_M PF00361.20 ACL95481.3 - 5.9e-89 298.1 27.8 5.9e-89 298.1 27.8 1.7 2 0 0 2 2 2 1 Proton-conducting membrane transporter Oxidored_q5_N PF01059.17 ACL95481.3 - 4.9e-06 26.6 0.5 4.9e-06 26.6 0.5 3.7 4 1 1 5 5 5 1 NADH-ubiquinone oxidoreductase chain 4, amino terminus CCB1 PF12046.8 ACL95481.3 - 0.87 8.9 0.0 0.87 8.9 0.0 4.5 5 1 1 6 6 6 0 Cofactor assembly of complex C subunit B Proton_antipo_M PF00361.20 ACL95482.1 - 7.1e-91 304.4 23.0 1.7e-90 303.2 23.0 1.6 1 0 0 1 1 1 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 ACL95482.1 - 5.9e-24 83.9 0.7 5.9e-24 83.9 0.7 3.8 4 0 0 4 4 4 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus NADH5_C PF06455.11 ACL95482.1 - 4.5e-12 45.9 2.5 2.7e-06 27.1 0.0 4.4 4 1 0 4 4 4 3 NADH dehydrogenase subunit 5 C-terminus Proton_antipo_C PF01010.19 ACL95482.1 - 0.00016 21.4 2.6 0.0004 20.1 0.5 2.5 2 1 0 2 2 2 1 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus Oxidored_q2 PF00420.24 ACL95483.1 - 6e-25 86.9 11.6 7e-25 86.7 11.6 1.0 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF5392 PF17370.2 ACL95483.1 - 0.36 10.9 3.7 0.41 10.7 3.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5392) Gram_pos_anchor PF00746.21 ACL95483.1 - 0.37 10.8 3.9 1.8 8.6 0.2 2.4 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Herpes_LMP1 PF05297.11 ACL95483.1 - 4.8 6.3 5.6 5.3 6.1 5.6 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Tetraspanin PF00335.20 ACL95483.1 - 8.7 6.0 15.6 0.73 9.5 6.4 2.0 1 1 1 2 2 2 0 Tetraspanin family Oxidored_q3 PF00499.20 ACL95484.2 - 1.5e-39 135.0 21.1 1.5e-39 135.0 21.1 1.5 1 1 1 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Bac_export_2 PF01312.19 ACL95484.2 - 8.4 5.5 13.6 11 5.1 13.6 1.1 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Fer4 PF00037.27 ACL95485.2 - 7.3e-14 50.9 18.0 3.9e-08 32.8 5.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 ACL95485.2 - 1.4e-13 51.2 9.9 2.3e-13 50.5 9.9 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 ACL95485.2 - 1.5e-11 45.1 5.8 9.6e-06 26.5 0.1 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 ACL95485.2 - 1.5e-10 41.0 3.8 9.9e-05 22.4 0.3 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 ACL95485.2 - 7.9e-10 38.8 8.2 1.3e-09 38.0 8.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 ACL95485.2 - 1.8e-09 37.5 20.6 2.8e-06 27.3 12.5 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 ACL95485.2 - 8.7e-08 32.5 18.1 0.0001 22.7 11.2 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 ACL95485.2 - 3.8e-07 29.9 18.2 0.00025 21.0 5.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 ACL95485.2 - 1.4e-06 28.0 11.7 0.0047 16.9 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 ACL95485.2 - 2.8e-06 27.4 10.2 0.00019 21.7 1.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 ACL95485.2 - 0.00012 22.6 11.6 0.01 16.3 12.3 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 ACL95485.2 - 0.0039 18.0 16.5 0.0096 16.8 4.2 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_13 PF13370.6 ACL95485.2 - 0.0046 17.5 14.8 0.3 11.7 2.8 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 ACL95485.2 - 0.012 15.8 5.0 0.36 11.1 0.3 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_18 PF13746.6 ACL95485.2 - 0.02 15.1 8.9 1.8 8.8 9.0 2.2 1 1 0 1 1 1 0 4Fe-4S dicluster domain ETF_QO PF05187.13 ACL95485.2 - 0.17 12.0 5.9 1.1 9.4 0.7 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 ACL95485.2 - 0.24 12.3 11.1 1.8 9.5 1.7 2.3 1 1 2 3 3 3 0 4Fe-4S dicluster domain DUF4995 PF16386.5 ACL95486.1 - 0.12 12.4 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function NADHdh PF00146.21 ACL95487.1 - 6.9e-117 390.0 26.1 8.6e-117 389.7 26.1 1.0 1 0 0 1 1 1 1 NADH dehydrogenase Molybdopterin PF00384.22 ACL95488.1 - 2.8e-76 257.2 0.0 3.9e-75 253.4 0.0 2.0 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.9 ACL95488.1 - 1.2e-16 60.0 0.1 1.2e-16 60.0 0.1 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 ACL95488.1 - 2.2e-12 47.4 0.0 6.2e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2_4 PF13510.6 ACL95488.1 - 2.9e-12 46.5 0.0 6.6e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 ACL95488.1 - 1.1e-08 34.9 1.0 2.3e-08 33.9 0.1 2.0 1 1 1 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 ACL95488.1 - 0.011 15.5 3.8 0.15 11.8 1.3 3.0 2 2 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Antimicrobial18 PF08130.11 ACL95488.1 - 0.18 12.0 0.1 0.48 10.6 0.1 1.7 1 0 0 1 1 1 0 Type A lantibiotic family Complex1_51K PF01512.17 ACL95489.1 - 3.7e-49 166.5 0.0 5.8e-49 165.9 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 ACL95489.1 - 6.5e-30 103.0 0.1 1.3e-29 102.1 0.1 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 ACL95489.1 - 1.1e-07 31.5 0.0 2.2e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 SLBB domain DUF3568 PF12092.8 ACL95489.1 - 0.093 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) DUF3040 PF11239.8 ACL95490.1 - 0.0043 17.3 0.3 0.0052 17.0 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3040) DUF2189 PF09955.9 ACL95490.1 - 0.014 15.7 2.8 0.5 10.6 0.0 2.0 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2189) DUF202 PF02656.15 ACL95490.1 - 1.2 9.7 7.9 8.3 6.9 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF202) DUF3099 PF11298.8 ACL95491.1 - 0.11 12.7 2.4 0.13 12.4 2.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3099) 2Fe-2S_thioredx PF01257.19 ACL95492.1 - 5.7e-54 181.9 0.0 6.8e-54 181.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Sigma70_r3 PF04539.16 ACL95492.1 - 0.053 13.6 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 Sigma-70 region 3 EF1G PF00647.19 ACL95492.1 - 0.13 12.3 0.2 0.21 11.6 0.2 1.3 1 0 0 1 1 1 0 Elongation factor 1 gamma, conserved domain SnoaL_2 PF12680.7 ACL95493.1 - 6.7e-15 55.6 1.0 7.5e-15 55.4 1.0 1.0 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 ACL95493.1 - 3.8e-06 26.7 0.3 1.8e-05 24.6 0.3 1.8 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_3 PF13474.6 ACL95493.1 - 0.00046 20.4 0.0 0.00056 20.2 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 ACL95493.1 - 0.0019 18.6 0.1 0.0024 18.2 0.1 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) LEH PF07858.12 ACL95493.1 - 0.0028 17.7 0.2 0.0035 17.4 0.2 1.0 1 0 0 1 1 1 1 Limonene-1,2-epoxide hydrolase catalytic domain Complex1_49kDa PF00346.19 ACL95494.1 - 7.1e-122 405.7 0.0 8.9e-122 405.4 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit CarbpepA_inh PF02977.15 ACL95494.1 - 0.079 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Carboxypeptidase A inhibitor NiFeSe_Hases PF00374.19 ACL95494.1 - 0.11 11.4 0.0 0.25 10.2 0.0 1.6 2 0 0 2 2 2 0 Nickel-dependent hydrogenase MerC PF03203.14 ACL95495.1 - 0.13 12.7 8.0 0.24 11.9 8.1 1.5 1 1 0 1 1 1 0 MerC mercury resistance protein TMEM100 PF16311.5 ACL95495.1 - 1.8 8.1 4.4 0.92 9.1 2.0 1.6 1 1 0 1 1 1 0 Transmembrane protein 100 TMEM43 PF07787.12 ACL95495.1 - 4.1 6.7 11.2 0.25 10.7 4.3 1.9 1 1 1 2 2 2 0 Transmembrane protein 43 UPF0182 PF03699.13 ACL95495.1 - 5.3 5.0 5.9 11 4.0 5.9 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0182) Complex1_30kDa PF00329.19 ACL95496.1 - 4.9e-48 162.8 0.1 6.3e-48 162.4 0.1 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Oxidored_q6 PF01058.22 ACL95497.1 - 2.4e-24 85.6 0.1 3.1e-24 85.3 0.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Secapin PF17521.2 ACL95497.1 - 0.047 13.5 0.5 0.28 11.0 0.0 2.4 2 0 0 2 2 2 0 Honey bee peptides Oxidored_q4 PF00507.19 ACL95498.1 - 2.2e-37 127.2 2.9 2.2e-37 127.2 2.9 1.3 2 0 0 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 DUF4307 PF14155.6 ACL95498.1 - 0.092 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) Bac_luciferase PF00296.20 ACL95499.1 - 2.8e-40 138.7 7.1 6.7e-40 137.4 7.1 1.6 1 1 0 1 1 1 1 Luciferase-like monooxygenase Glycos_transf_1 PF00534.20 ACL95500.1 - 9.1e-23 80.7 0.0 3.5e-22 78.8 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ACL95500.1 - 7.2e-21 75.0 0.9 1.7e-19 70.6 0.5 2.5 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ACL95500.1 - 1.2e-17 64.4 1.6 1.1e-16 61.3 0.7 2.3 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 ACL95500.1 - 7.9e-10 39.4 8.4 7.9e-10 39.4 8.4 3.1 2 2 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 ACL95500.1 - 4.6e-05 23.7 0.1 0.0001 22.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Bac_DNA_binding PF00216.21 ACL95501.1 - 2.5e-29 101.3 0.5 2.8e-29 101.2 0.5 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 ACL95501.1 - 2e-08 34.4 0.0 2.1e-08 34.3 0.0 1.0 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_bac_2 PF18175.1 ACL95501.1 - 2.2e-05 24.2 0.0 3.2e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 HU-CCDC81_euk_2 PF18289.1 ACL95501.1 - 4.3e-05 23.6 0.1 6.2e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 HU-CCDC81_euk_1 PF14908.6 ACL95501.1 - 0.013 15.6 0.0 0.015 15.4 0.0 1.1 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 1 DUF2267 PF10025.9 ACL95501.1 - 0.083 13.2 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) Phage_connect_1 PF05135.13 ACL95501.1 - 0.16 12.5 0.0 0.18 12.3 0.0 1.1 1 0 0 1 1 1 0 Phage gp6-like head-tail connector protein Lon_C PF05362.13 ACL95502.1 - 3.3e-97 324.0 2.1 5.2e-97 323.3 2.1 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 ACL95502.1 - 1.5e-42 145.8 0.0 1.5e-42 145.8 0.0 1.9 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 ACL95502.1 - 6.5e-21 75.1 0.0 2.8e-20 73.1 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ACL95502.1 - 2.6e-10 40.4 0.0 7.7e-10 38.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 ACL95502.1 - 4.3e-09 36.3 0.1 9.2e-09 35.2 0.1 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_PrkA PF08298.11 ACL95502.1 - 2.8e-06 26.5 0.1 1.3e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 PrkA AAA domain AAA_16 PF13191.6 ACL95502.1 - 8.1e-05 23.1 1.0 0.00072 20.0 0.0 2.9 3 0 0 3 3 2 1 AAA ATPase domain AAA_23 PF13476.6 ACL95502.1 - 0.0017 18.9 1.3 1.7 9.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 ACL95502.1 - 0.0019 18.0 0.0 0.0051 16.6 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 ACL95502.1 - 0.0029 17.7 0.0 0.0087 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 ACL95502.1 - 0.0038 17.8 0.3 0.017 15.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 ACL95502.1 - 0.0043 17.1 0.0 0.017 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ACL95502.1 - 0.0059 16.9 0.1 0.063 13.6 0.2 2.6 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 ACL95502.1 - 0.012 15.5 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 ACL95502.1 - 0.027 14.4 0.0 0.076 12.9 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 ACL95502.1 - 0.032 14.0 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 ACL95502.1 - 0.032 14.4 0.1 0.082 13.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ACL95502.1 - 0.07 13.6 1.7 0.79 10.2 0.0 2.8 2 1 0 2 2 2 0 ABC transporter Viral_helicase1 PF01443.18 ACL95502.1 - 0.084 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase LPD28 PF18843.1 ACL95502.1 - 0.087 12.4 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Large polyvalent protein associated domain 28 Imm70 PF15601.6 ACL95502.1 - 0.091 12.3 0.3 0.25 10.9 0.1 1.8 2 0 0 2 2 2 0 Immunity protein 70 TsaE PF02367.17 ACL95502.1 - 0.11 12.4 0.0 0.36 10.8 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 ACL95502.1 - 0.12 12.8 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase SKI PF01202.22 ACL95502.1 - 2.1 8.5 5.5 0.41 10.8 0.1 2.2 2 0 0 2 2 2 0 Shikimate kinase CCDC-167 PF15188.6 ACL95502.1 - 7.8 6.9 9.0 0.87 10.0 2.6 2.4 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 AAA_2 PF07724.14 ACL95504.1 - 1.7e-49 168.2 0.0 2.9e-49 167.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) zf-C4_ClpX PF06689.13 ACL95504.1 - 2.7e-20 72.0 3.8 6.7e-20 70.7 3.8 1.7 1 0 0 1 1 1 1 ClpX C4-type zinc finger AAA PF00004.29 ACL95504.1 - 1.1e-16 61.4 0.0 3.3e-16 59.9 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 ACL95504.1 - 2.5e-15 56.3 0.2 8.4e-15 54.6 0.1 1.9 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 ACL95504.1 - 1.2e-06 28.6 0.0 1.2e-05 25.3 0.2 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) MCM PF00493.23 ACL95504.1 - 3.5e-06 26.3 0.1 5.8e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain RuvB_N PF05496.12 ACL95504.1 - 6.4e-06 26.0 0.4 2.3e-05 24.2 0.4 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 ACL95504.1 - 6.4e-06 25.7 0.3 0.001 18.5 0.5 2.8 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 ACL95504.1 - 2.4e-05 24.1 0.0 0.0095 15.6 0.0 2.8 2 1 1 3 3 3 1 Sigma-54 interaction domain AAA_22 PF13401.6 ACL95504.1 - 4.5e-05 23.7 0.4 0.0011 19.2 0.4 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ACL95504.1 - 0.00038 20.9 0.3 0.0018 18.7 0.3 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 ACL95504.1 - 0.001 18.6 0.0 0.0021 17.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region PduV-EutP PF10662.9 ACL95504.1 - 0.0011 18.7 0.1 0.24 11.1 0.1 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.17 ACL95504.1 - 0.0013 18.5 0.0 0.0035 17.1 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 ACL95504.1 - 0.0016 18.5 0.0 0.0049 17.0 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain TIP49 PF06068.13 ACL95504.1 - 0.0041 16.4 0.1 0.0098 15.1 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain T2SSE PF00437.20 ACL95504.1 - 0.0057 15.8 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein TsaE PF02367.17 ACL95504.1 - 0.012 15.6 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 ACL95504.1 - 0.016 15.2 0.0 0.26 11.2 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 ACL95504.1 - 0.02 14.5 0.0 0.058 13.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 ACL95504.1 - 0.02 15.3 0.0 0.065 13.6 0.0 1.9 1 1 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 ACL95504.1 - 0.024 15.2 0.0 0.081 13.4 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 ACL95504.1 - 0.033 13.9 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 ACL95504.1 - 0.033 13.6 0.0 0.068 12.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_3 PF07726.11 ACL95504.1 - 0.033 14.0 0.1 0.16 11.8 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 ACL95504.1 - 0.035 14.1 0.0 0.067 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 ACL95504.1 - 0.045 13.8 0.0 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 ACL95504.1 - 0.045 14.3 0.0 0.13 12.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain ATPase PF06745.13 ACL95504.1 - 0.053 12.8 1.4 0.52 9.6 0.1 2.3 1 1 1 2 2 2 0 KaiC AAA_21 PF13304.6 ACL95504.1 - 0.09 12.6 0.0 0.2 11.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_19 PF13245.6 ACL95504.1 - 0.15 12.4 2.2 2.8 8.2 0.2 2.9 3 1 1 4 4 3 0 AAA domain Rad17 PF03215.15 ACL95504.1 - 0.15 11.9 0.0 0.41 10.5 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_28 PF13521.6 ACL95504.1 - 0.15 12.3 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ACL95504.1 - 0.15 12.2 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 ACL95504.1 - 0.22 10.6 0.0 0.76 8.8 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 HAD PF12710.7 ACL95505.1 - 7.8e-29 101.4 0.2 9.1e-29 101.2 0.2 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ACL95505.1 - 4.9e-08 33.5 2.1 2.5e-06 27.9 2.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase CLP_protease PF00574.23 ACL95506.1 - 5.4e-85 283.9 0.0 6.3e-85 283.6 0.0 1.0 1 0 0 1 1 1 1 Clp protease Trigger_C PF05698.14 ACL95507.1 - 1.3e-45 155.3 0.7 6.6e-43 146.5 0.1 2.6 3 0 0 3 3 3 2 Bacterial trigger factor protein (TF) C-terminus Trigger_N PF05697.13 ACL95507.1 - 3.7e-36 124.6 0.2 3.7e-36 124.6 0.2 2.2 2 0 0 2 2 2 1 Bacterial trigger factor protein (TF) FKBP_C PF00254.28 ACL95507.1 - 5.9e-13 49.0 0.3 1.5e-12 47.7 0.3 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PALP PF00291.25 ACL95507.1 - 0.067 12.6 0.1 0.43 9.9 0.0 2.0 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme TBPIP PF07106.13 ACL95507.1 - 0.11 12.4 0.1 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 TBPIP/Hop2 winged helix domain Carb_kinase PF01256.17 ACL95508.1 - 2e-47 161.8 1.8 3e-47 161.2 1.8 1.2 1 0 0 1 1 1 1 Carbohydrate kinase YjeF_N PF03853.15 ACL95508.1 - 3.5e-36 124.7 0.2 1.8e-35 122.3 0.0 2.1 2 1 1 3 3 3 1 YjeF-related protein N-terminus His_Phos_1 PF00300.22 ACL95509.1 - 3.5e-19 69.3 0.2 1.1e-18 67.6 0.2 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) TLP1_add_C PF18313.1 ACL95510.1 - 2.9e-15 56.0 0.0 6e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Thiolase-like protein type 1 additional C-terminal domain ketoacyl-synt PF00109.26 ACL95510.1 - 0.031 13.8 0.0 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Thiolase_C PF02803.18 ACL95510.1 - 0.068 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Thiolase, C-terminal domain P-II PF00543.22 ACL95511.1 - 6.6e-43 145.5 0.7 7.4e-43 145.3 0.7 1.0 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II DUF3240 PF11582.8 ACL95511.1 - 0.0019 18.3 0.0 0.0025 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3240) DUF190 PF02641.15 ACL95511.1 - 0.019 15.3 0.1 0.028 14.7 0.1 1.4 1 1 0 1 1 1 0 Uncharacterized ACR, COG1993 DUF2344 PF10105.9 ACL95511.1 - 0.05 13.4 0.0 0.054 13.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) DUF2007 PF09413.10 ACL95511.1 - 0.073 13.2 0.1 0.22 11.7 0.1 1.9 1 1 0 1 1 1 0 Putative prokaryotic signal transducing protein Gln-synt_C PF00120.24 ACL95512.1 - 3.3e-136 453.8 0.0 3.9e-136 453.6 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 ACL95512.1 - 1.6e-29 101.5 0.6 3e-29 100.6 0.6 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain TonB_dep_Rec PF00593.24 ACL95513.2 - 1.3e-37 130.8 24.6 1.9e-37 130.3 24.6 1.2 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 ACL95513.2 - 1.2e-13 51.5 0.4 2e-12 47.6 0.2 2.5 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain OMP_b-brl PF13505.6 ACL95513.2 - 3.1e-05 24.2 0.9 3.1e-05 24.2 0.9 5.1 3 1 1 5 5 5 2 Outer membrane protein beta-barrel domain ABM PF03992.16 ACL95514.2 - 4.5e-13 49.1 0.0 6e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Amidohydro_3 PF07969.11 ACL95515.2 - 1.4e-20 74.2 1.2 4.5e-14 52.8 0.2 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 ACL95515.2 - 3.4e-17 62.8 0.1 9.2e-14 51.5 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 ACL95516.1 - 5.3e-12 45.9 1.8 8.7e-09 35.3 0.0 2.7 2 1 1 3 3 3 2 Amidohydrolase family Amidohydro_1 PF01979.20 ACL95516.1 - 1.3e-09 37.8 0.0 2.1e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family DNA_gyraseB PF00204.25 ACL95517.1 - 2.9e-42 144.1 0.0 4.5e-42 143.5 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase B DNA_gyraseB_C PF00986.21 ACL95517.1 - 1e-23 83.3 0.8 2.1e-23 82.3 0.8 1.6 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 ACL95517.1 - 2.5e-20 73.0 0.0 4.7e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 ACL95517.1 - 4.6e-17 62.1 0.0 8.6e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Toprim domain HATPase_c_3 PF13589.6 ACL95517.1 - 0.0035 17.2 0.0 0.011 15.6 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF5560 PF17715.1 ACL95518.1 - 0.042 13.3 4.4 0.06 12.8 4.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5560) Carboxyl_trans PF01039.22 ACL95519.1 - 6.5e-198 658.4 0.3 7.3e-198 658.2 0.3 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain OHCU_decarbox PF09349.10 ACL95519.1 - 0.021 15.3 0.0 0.065 13.7 0.0 1.8 2 0 0 2 2 2 0 OHCU decarboxylase MdcE PF06833.11 ACL95519.1 - 0.036 13.6 0.2 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) UPF0060 PF02694.15 ACL95520.1 - 8.4e-31 106.4 9.4 9.1e-31 106.3 9.4 1.0 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family Phage_holin_2_1 PF04971.12 ACL95520.1 - 0.0037 17.2 4.9 0.21 11.6 1.3 2.2 2 0 0 2 2 2 2 Bacteriophage P21 holin S EamA PF00892.20 ACL95520.1 - 0.013 15.7 7.9 0.019 15.1 7.9 1.3 1 1 0 1 1 1 0 EamA-like transporter family RseC_MucC PF04246.12 ACL95520.1 - 4.6 7.2 9.1 3.3 7.7 4.6 2.0 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC ATP12 PF07542.11 ACL95521.3 - 1.3e-31 109.4 0.1 1.9e-31 108.8 0.1 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein DUF1800 PF08811.11 ACL95522.1 - 1.2e-130 436.4 0.7 1.4e-130 436.2 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1800) DUF1501 PF07394.12 ACL95523.1 - 1.1e-46 159.7 1.1 2.4e-46 158.5 1.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1501) PseudoU_synth_2 PF00849.22 ACL95524.1 - 1.3e-34 119.6 0.0 1.8e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase CRCB PF02537.15 ACL95525.1 - 5.1e-22 78.0 12.6 6e-22 77.8 12.6 1.0 1 0 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) GGDEF PF00990.21 ACL95526.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain SMC_N PF02463.19 ACL95527.1 - 1.8e-15 57.0 0.0 4.8e-15 55.6 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ACL95527.1 - 1.8e-07 31.9 0.1 8.4e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 ACL95527.1 - 5.1e-07 29.8 0.0 0.04 13.7 0.0 2.5 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ACL95527.1 - 0.00035 20.3 0.6 0.00083 19.1 0.6 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 ACL95527.1 - 0.012 15.9 0.3 0.14 12.4 0.1 2.9 3 1 0 3 3 3 0 AAA domain ABC_tran PF00005.27 ACL95527.1 - 0.061 13.8 0.3 0.24 11.9 0.3 2.0 1 0 0 1 1 1 0 ABC transporter YfiO PF13525.6 ACL95528.1 - 1.2e-53 181.9 0.9 1.5e-53 181.6 0.9 1.1 1 0 0 1 1 1 1 Outer membrane lipoprotein TPR_18 PF13512.6 ACL95528.1 - 2.3e-21 76.4 2.7 1.4e-20 73.9 2.8 2.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 ACL95528.1 - 6e-17 61.1 5.5 3e-05 24.4 0.2 5.6 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 ACL95528.1 - 5.8e-12 46.1 3.0 0.00039 21.0 0.0 3.9 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 ACL95528.1 - 2.8e-09 37.0 5.9 1.1 10.3 0.0 5.6 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 ACL95528.1 - 2.1e-08 34.5 1.0 0.033 14.7 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 ACL95528.1 - 1.6e-07 30.9 5.4 0.048 13.8 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ACL95528.1 - 0.001 19.2 0.2 0.023 14.9 0.1 3.0 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 ACL95528.1 - 0.0012 19.2 0.9 0.077 13.4 0.0 3.0 2 1 0 3 3 3 1 Bacterial transcriptional activator domain TPR_12 PF13424.6 ACL95528.1 - 0.0027 17.9 4.9 0.41 11.0 0.1 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 ACL95528.1 - 0.016 15.1 5.2 3.4 7.7 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 ACL95528.1 - 0.044 13.4 0.1 0.9 9.2 0.0 2.6 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) LpxC PF03331.13 ACL95529.1 - 9.4e-102 340.1 0.0 1.1e-101 339.9 0.0 1.0 1 0 0 1 1 1 1 UDP-3-O-acyl N-acetylglycosamine deacetylase Peptidase_S9 PF00326.21 ACL95530.1 - 6.9e-61 205.4 1.6 1.2e-60 204.6 1.6 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 ACL95530.1 - 1.7e-17 62.9 8.4 7.8e-06 25.7 0.2 6.5 6 0 0 6 6 6 4 WD40-like Beta Propeller Repeat SGL PF08450.12 ACL95530.1 - 4.1e-07 29.8 0.1 0.00063 19.4 0.0 2.5 2 0 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region AXE1 PF05448.12 ACL95530.1 - 0.048 12.3 0.2 0.11 11.1 0.1 1.5 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Lactonase PF10282.9 ACL95530.1 - 0.12 11.7 0.0 30 3.7 0.0 2.9 2 1 0 3 3 3 0 Lactonase, 7-bladed beta-propeller SQS_PSY PF00494.19 ACL95531.1 - 3.6e-15 56.2 2.9 6.5e-15 55.3 2.9 1.5 1 1 0 1 1 1 1 Squalene/phytoene synthase Urate_ox_N PF06181.11 ACL95532.1 - 1.3e-16 60.9 16.6 1.9e-08 34.0 0.5 3.1 2 1 1 3 3 3 3 Urate oxidase N-terminal DUF498 PF04430.14 ACL95533.1 - 1.7e-28 98.8 0.0 1.9e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) SecD_SecF PF02355.16 ACL95534.1 - 3.9e-66 222.1 5.2 3.9e-66 222.1 5.2 1.5 2 0 0 2 2 2 1 Protein export membrane protein Sec_GG PF07549.14 ACL95534.1 - 5.6e-08 32.0 0.1 1.6e-07 30.6 0.1 1.8 1 0 0 1 1 1 1 SecD/SecF GG Motif ACR_tran PF00873.19 ACL95534.1 - 0.013 13.2 6.4 0.021 12.5 6.4 1.3 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family SecD_SecF PF02355.16 ACL95535.1 - 1.1e-17 64.0 11.1 1.8e-17 63.3 11.1 1.2 1 0 0 1 1 1 1 Protein export membrane protein Sec_GG PF07549.14 ACL95535.1 - 5.6e-07 28.8 0.0 1.2e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 SecD/SecF GG Motif SecD-TM1 PF13721.6 ACL95535.1 - 1.6e-05 25.3 1.4 0.06 13.8 0.4 2.8 2 0 0 2 2 2 2 SecD export protein N-terminal TM region MMPL PF03176.15 ACL95535.1 - 0.0007 18.6 19.0 0.0007 18.6 19.0 1.8 2 0 0 2 2 2 1 MMPL family PRA1 PF03208.19 ACL95535.1 - 0.79 9.3 5.1 3.2 7.4 5.2 2.0 1 1 0 1 1 1 0 PRA1 family protein YajC PF02699.15 ACL95536.1 - 5.5e-28 96.7 2.9 6.5e-28 96.4 2.9 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit T2SSM PF04612.12 ACL95536.1 - 0.01 15.9 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Orf78 PF06024.12 ACL95536.1 - 0.09 13.1 0.1 0.13 12.5 0.1 1.3 1 0 0 1 1 1 0 Orf78 (ac78) DUF815 PF05673.13 ACL95537.1 - 6.3e-86 287.6 0.0 7.4e-86 287.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 ACL95537.1 - 1.1e-06 29.2 0.4 3.4e-06 27.5 0.1 1.8 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 ACL95537.1 - 0.0043 17.5 0.0 0.029 14.8 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DnaB_bind PF10410.9 ACL95537.1 - 0.014 15.6 1.3 0.68 10.2 0.3 3.3 3 0 0 3 3 3 0 DnaB-helicase binding domain of primase AAA_8 PF12780.7 ACL95537.1 - 0.15 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 AAA_7 PF12775.7 ACL95537.1 - 0.2 11.2 0.0 0.36 10.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region HTH_31 PF13560.6 ACL95538.1 - 8e-15 54.9 6.1 2.1e-14 53.6 6.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 ACL95538.1 - 1.3e-13 50.8 0.1 2.6e-13 49.8 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 ACL95538.1 - 6.7e-09 35.6 0.0 1.3e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Cupin_2 PF07883.11 ACL95538.1 - 1.7e-06 27.7 0.0 2.7e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 Cupin domain HTH_26 PF13443.6 ACL95538.1 - 7.1e-06 26.4 0.1 1.3e-05 25.5 0.1 1.5 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_37 PF13744.6 ACL95538.1 - 0.00026 20.9 0.1 0.00056 19.8 0.1 1.6 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 ACL95538.1 - 0.00048 19.9 0.6 0.0014 18.4 0.6 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 ACL95538.1 - 0.0042 16.6 0.1 0.0085 15.6 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.6 ACL95538.1 - 0.064 13.1 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Phage_AlpA PF05930.12 ACL95538.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) Acetyltransf_1 PF00583.25 ACL95539.1 - 1.1e-10 41.8 0.0 1.3e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ACL95539.1 - 2.7e-08 33.8 0.0 3.4e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ACL95539.1 - 3.5e-08 33.8 0.1 5e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ACL95539.1 - 0.0048 16.9 0.0 0.0079 16.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_6 PF13480.7 ACL95539.1 - 0.017 15.2 1.4 0.024 14.8 1.4 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ACL95539.1 - 0.066 13.4 0.1 0.099 12.8 0.1 1.2 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PanZ PF12568.8 ACL95539.1 - 0.18 11.5 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ LysM PF01476.20 ACL95540.1 - 2.5e-45 152.3 0.0 5.4e-11 42.4 0.0 4.5 4 0 0 4 4 4 4 LysM domain Peptidase_M23 PF01551.22 ACL95540.1 - 8.8e-30 102.8 1.6 1.9e-28 98.5 0.1 3.7 3 1 0 3 3 3 1 Peptidase family M23 OapA PF04225.12 ACL95540.1 - 0.0008 19.5 0.1 2.6 8.2 0.0 3.5 3 0 0 3 3 3 2 Opacity-associated protein A LysM-like domain HTH_7 PF02796.15 ACL95540.1 - 0.054 13.6 0.1 16 5.6 0.0 3.4 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase ChapFlgA PF13144.6 ACL95540.1 - 0.079 13.0 1.7 22 5.2 0.0 4.1 4 1 1 5 5 5 0 Chaperone for flagella basal body P-ring formation HTH_3 PF01381.22 ACL95540.1 - 0.12 12.4 0.0 83 3.3 0.0 3.4 3 0 0 3 3 3 0 Helix-turn-helix RHH_4 PF13467.6 ACL95540.1 - 0.15 11.9 0.9 75 3.3 0.0 3.5 4 0 0 4 4 4 0 Ribbon-helix-helix domain Flagellin_IN PF07196.13 ACL95540.1 - 1.8 8.8 4.4 8.9 6.6 0.4 3.2 3 0 0 3 3 3 0 Flagellin hook IN motif PCMT PF01135.19 ACL95541.1 - 2.8e-57 193.9 0.0 3.3e-57 193.6 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 ACL95541.1 - 5.6e-06 25.6 0.0 7.9e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.6 ACL95541.1 - 0.00025 20.9 0.0 0.0004 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ACL95541.1 - 0.0041 17.8 0.0 0.0068 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 ACL95541.1 - 0.0044 16.7 0.0 0.0064 16.2 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_23 PF13489.6 ACL95541.1 - 0.025 14.4 0.0 0.05 13.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain DisA-linker PF10635.9 ACL95541.1 - 0.025 14.4 0.2 0.043 13.6 0.2 1.3 1 0 0 1 1 1 0 DisA bacterial checkpoint controller linker region Methyltransf_4 PF02390.17 ACL95541.1 - 0.075 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_11 PF08241.12 ACL95541.1 - 0.076 13.7 0.0 0.17 12.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 ACL95541.1 - 0.16 11.5 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 ACL95541.1 - 0.17 11.9 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain SurE PF01975.17 ACL95542.1 - 9e-57 192.0 0.0 1.2e-56 191.6 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE tRNA-synt_2b PF00587.25 ACL95543.1 - 1.1e-34 119.9 0.0 2.3e-34 118.9 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 ACL95543.1 - 2e-25 89.1 1.4 4.6e-25 88.0 1.4 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 ACL95543.1 - 0.11 11.9 3.9 0.22 10.9 3.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Rx_N PF18052.1 ACL95543.1 - 0.59 10.5 3.6 15 6.0 0.8 2.7 1 1 1 2 2 2 0 Rx N-terminal domain Uso1_p115_C PF04871.13 ACL95543.1 - 4.9 7.5 11.4 0.71 10.3 7.2 1.7 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region TatC PF00902.18 ACL95545.1 - 5.6e-67 225.6 19.2 6.4e-67 225.4 19.2 1.0 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) MttA_Hcf106 PF02416.16 ACL95546.1 - 3.9e-06 26.1 0.1 6.7e-06 25.3 0.1 1.5 1 0 0 1 1 1 1 mttA/Hcf106 family MttA_Hcf106 PF02416.16 ACL95547.1 - 4.6e-07 29.1 0.1 5.2e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 mttA/Hcf106 family YfhD PF14151.6 ACL95547.1 - 0.065 13.4 0.2 0.068 13.3 0.2 1.1 1 0 0 1 1 1 0 YfhD-like protein Sperm_Ag_HE2 PF05324.13 ACL95547.1 - 0.096 13.2 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 Sperm antigen HE2 SMC_ScpB PF04079.16 ACL95548.1 - 1.5e-47 161.2 0.0 1.8e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 Segregation and condensation complex subunit ScpB HTH_27 PF13463.6 ACL95548.1 - 0.11 13.0 0.1 2 9.0 0.0 2.8 3 1 0 3 3 3 0 Winged helix DNA-binding domain SMC_ScpA PF02616.14 ACL95549.1 - 7e-10 39.2 1.6 3.5e-09 36.9 1.6 1.9 1 1 0 1 1 1 1 Segregation and condensation protein ScpA Glyco_hydro_3 PF00933.21 ACL95550.1 - 1.1e-51 176.1 0.0 1.4e-51 175.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain HHV-1_VABD PF16852.5 ACL95550.1 - 0.0097 15.9 1.7 0.012 15.6 0.2 1.9 2 0 0 2 2 2 1 Herpes viral adaptor-to-host cellular mRNA binding domain SPOR PF05036.13 ACL95551.1 - 1.5e-13 50.9 0.3 3.1e-13 49.9 0.3 1.5 1 0 0 1 1 1 1 Sporulation related domain Col_cuticle_N PF01484.17 ACL95551.1 - 0.41 10.8 1.6 0.89 9.7 1.6 1.5 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain HD_assoc PF13286.6 ACL95552.1 - 3.8e-29 101.1 0.2 9.3e-29 99.8 0.2 1.7 1 0 0 1 1 1 1 Phosphohydrolase-associated domain HD PF01966.22 ACL95552.1 - 3.2e-16 59.7 0.2 7.5e-16 58.5 0.1 1.7 2 0 0 2 2 2 1 HD domain HDOD PF08668.12 ACL95552.1 - 0.00012 21.6 0.0 0.00039 20.0 0.0 1.8 2 0 0 2 2 2 1 HDOD domain Fe-S_biosyn PF01521.20 ACL95553.1 - 7.7e-20 71.2 0.0 8.6e-20 71.0 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF3117 PF11314.8 ACL95553.1 - 0.074 12.9 0.2 0.16 11.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3117) CCB1 PF12046.8 ACL95554.1 - 0.029 13.7 3.8 0.057 12.8 3.8 1.5 1 1 0 1 1 1 0 Cofactor assembly of complex C subunit B DUF2839 PF10999.8 ACL95554.1 - 7.8 6.9 10.6 0.35 11.3 4.5 1.9 2 1 0 3 3 3 0 Protein of unknown function (DUF2839) Exo_endo_phos PF03372.23 ACL95555.1 - 3.5e-22 79.1 0.1 4.2e-22 78.8 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LysE PF01810.18 ACL95557.1 - 2.2e-26 92.5 4.4 3.2e-26 92.0 4.4 1.2 1 0 0 1 1 1 1 LysE type translocator DUF5337 PF17272.2 ACL95557.1 - 0.8 9.6 13.5 1.3 8.9 1.4 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5337) DUF885 PF05960.11 ACL95558.2 - 1.5e-151 506.7 12.3 1.7e-151 506.5 12.3 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) TAT_signal PF10518.9 ACL95558.2 - 0.097 12.5 0.2 0.097 12.5 0.2 2.6 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence GFO_IDH_MocA PF01408.22 ACL95559.1 - 2.5e-24 86.4 0.3 4.6e-24 85.5 0.3 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 ACL95559.1 - 0.0016 19.1 0.5 0.0029 18.2 0.5 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain CoA_binding PF02629.19 ACL95559.1 - 0.078 13.7 2.6 0.25 12.1 0.3 2.3 2 0 0 2 2 2 0 CoA binding domain 2-Hacid_dh_C PF02826.19 ACL95559.1 - 0.1 11.9 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_N_2 PF16884.5 ACL95560.1 - 5.6e-41 138.8 0.1 2e-40 137.0 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 ACL95560.1 - 2.6e-23 82.4 0.0 5.4e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ACL95560.1 - 5.8e-12 46.8 0.0 1.9e-11 45.2 0.0 1.9 3 0 0 3 3 3 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 ACL95560.1 - 0.032 14.5 0.0 0.059 13.6 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain CusF_Ec PF11604.8 ACL95561.1 - 1.8e-06 27.8 0.0 2.4e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Copper binding periplasmic protein CusF LPAM_2 PF13627.6 ACL95561.1 - 0.1 12.5 1.7 0.2 11.5 1.7 1.5 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site Glyco_trans_2_3 PF13632.6 ACL95562.1 - 1.7e-15 57.4 2.9 1.7e-15 57.4 2.9 2.6 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 ACL95562.1 - 2.9e-10 40.2 0.0 4.7e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ACL95562.1 - 4.9e-10 39.2 0.0 9.2e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 PrgI PF12666.7 ACL95562.1 - 0.093 13.5 2.6 0.22 12.2 0.0 2.8 2 0 0 2 2 2 0 PrgI family protein DUF2794 PF10984.8 ACL95562.1 - 0.19 11.8 0.0 0.49 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2794) MatE PF01554.18 ACL95564.1 - 2.1e-40 138.0 38.8 1.1e-23 83.6 14.1 2.9 2 1 1 3 3 3 2 MatE Polysacc_synt_C PF14667.6 ACL95564.1 - 2.6e-06 27.6 5.1 2.6e-06 27.6 5.1 4.6 3 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain PepSY_like PF11396.8 ACL95565.1 - 1.1e-05 25.9 0.2 0.0029 18.1 0.0 2.4 2 1 1 3 3 3 2 Putative beta-lactamase-inhibitor-like, PepSY-like PepSY_2 PF13670.6 ACL95565.1 - 0.0068 16.4 0.1 0.017 15.1 0.0 1.7 2 0 0 2 2 2 1 Peptidase propeptide and YPEB domain MRP_L53 PF10780.9 ACL95565.1 - 0.094 12.9 0.1 0.46 10.7 0.0 2.0 2 0 0 2 2 2 0 39S ribosomal protein L53/MRP-L53 Glyoxalase PF00903.25 ACL95566.1 - 8.2e-17 61.6 0.1 9.2e-17 61.4 0.1 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ACL95566.1 - 1.2e-06 29.2 0.3 1.5e-06 29.0 0.3 1.0 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 ACL95566.1 - 0.0005 20.3 0.1 0.0007 19.8 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 ACL95566.1 - 0.0057 16.8 0.2 0.27 11.3 0.2 2.1 1 1 0 1 1 1 1 Glyoxalase-like domain ThuA PF06283.11 ACL95567.1 - 6.5e-39 134.3 0.1 9.1e-39 133.9 0.1 1.2 1 0 0 1 1 1 1 Trehalose utilisation PrmC_N PF17827.1 ACL95567.1 - 0.096 13.3 0.5 7.7 7.2 1.5 3.1 3 1 0 3 3 3 0 PrmC N-terminal domain DUF2239 PF09998.9 ACL95568.1 - 1.5e-66 223.7 1.9 1.8e-66 223.5 1.9 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2239) GIY-YIG PF01541.24 ACL95569.1 - 0.0089 16.3 0.0 0.02 15.2 0.0 1.7 1 1 0 1 1 1 1 GIY-YIG catalytic domain Reg_prop PF07494.11 ACL95569.1 - 0.067 13.4 0.4 49 4.6 0.0 3.2 3 0 0 3 3 3 0 Two component regulator propeller MIR PF02815.19 ACL95570.1 - 0.052 13.4 0.0 0.07 13.0 0.0 1.1 1 0 0 1 1 1 0 MIR domain Plug PF07715.15 ACL95571.1 - 6.4e-06 26.7 0.2 0.00024 21.7 0.1 3.5 2 1 0 2 2 2 1 TonB-dependent Receptor Plug Domain BBP2 PF07642.11 ACL95571.1 - 0.0043 16.3 0.6 0.019 14.1 0.1 2.1 2 0 0 2 2 2 1 Putative beta-barrel porin-2, OmpL-like. bbp2 PapD_N PF00345.20 ACL95571.1 - 0.06 13.3 0.1 0.18 11.7 0.1 1.7 2 0 0 2 2 2 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Peptidase_S41 PF03572.18 ACL95573.1 - 9.5e-27 93.6 0.0 1.3e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S41 LPAM_1 PF08139.12 ACL95573.1 - 1.2 9.8 3.3 2.8 8.6 3.3 1.7 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site ThiC_Rad_SAM PF01964.18 ACL95574.1 - 3e-200 665.3 0.0 3.6e-200 665.1 0.0 1.0 1 0 0 1 1 1 1 Radical SAM ThiC family ThiC-associated PF13667.6 ACL95574.1 - 6.7e-24 83.5 0.0 1.4e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 ThiC-associated domain TPR_2 PF07719.17 ACL95576.1 - 5.6e-15 54.2 1.2 4.8e-06 26.3 0.3 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 ACL95576.1 - 1.5e-14 53.1 1.4 6.6e-07 28.9 0.1 3.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 ACL95576.1 - 5.4e-10 39.3 1.2 5.6e-05 23.2 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 ACL95576.1 - 1e-09 37.8 0.0 0.00042 20.3 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 ACL95576.1 - 6.1e-06 25.8 0.5 0.23 11.2 0.1 3.8 2 2 2 4 4 4 2 TPR repeat TPR_16 PF13432.6 ACL95576.1 - 3.6e-05 24.3 9.9 0.00014 22.4 0.7 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 ACL95576.1 - 0.00083 19.6 1.1 26 5.5 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 ACL95576.1 - 0.00091 19.5 0.4 1 9.7 0.2 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 ACL95576.1 - 0.097 13.2 2.3 3.8 8.1 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 ACL95576.1 - 0.1 13.4 9.0 0.15 12.9 0.2 3.8 2 1 3 5 5 5 0 Tetratricopeptide repeat PALP PF00291.25 ACL95577.1 - 1e-52 179.4 3.3 1.2e-52 179.2 3.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Asp_Glu_race PF01177.22 ACL95578.1 - 8.9e-46 156.5 0.0 1e-45 156.4 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase PALP PF00291.25 ACL95578.1 - 0.0047 16.4 1.3 0.0066 15.9 1.3 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CHAT PF12770.7 ACL95578.1 - 0.16 11.4 0.8 0.23 10.8 0.8 1.5 1 1 0 1 1 1 0 CHAT domain Amdase PF17645.1 ACL95578.1 - 0.25 10.9 6.3 0.55 9.8 0.2 3.0 1 1 2 3 3 3 0 Arylmalonate decarboxylase Pec_lyase PF09492.10 ACL95580.1 - 2.1e-31 109.4 0.1 1.9e-25 89.8 0.0 3.1 2 1 0 2 2 2 2 Pectic acid lyase Glyco_hydro_127 PF07944.12 ACL95580.1 - 6.1e-05 21.7 0.0 0.0032 16.0 0.0 2.3 1 1 0 2 2 2 1 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_88 PF07470.13 ACL95580.1 - 0.00016 20.9 1.0 0.019 14.0 0.0 3.3 3 2 1 4 4 4 1 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 ACL95580.1 - 0.0008 19.0 0.6 0.059 12.9 0.2 2.9 2 1 0 2 2 2 1 D-glucuronyl C5-epimerase C-terminus LANC_like PF05147.13 ACL95580.1 - 0.01 14.4 0.0 6.3 5.3 0.0 3.1 3 0 0 3 3 3 0 Lanthionine synthetase C-like protein Prenyltrans PF00432.21 ACL95580.1 - 0.044 13.5 0.1 6.2 6.7 0.0 2.9 3 0 0 3 3 3 0 Prenyltransferase and squalene oxidase repeat Sulfotransfer_2 PF03567.14 ACL95581.1 - 0.024 14.6 0.0 0.3 10.9 0.0 2.3 1 1 0 1 1 1 0 Sulfotransferase family rve_3 PF13683.6 ACL95581.1 - 0.086 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain Polyketide_cyc PF03364.20 ACL95582.1 - 1.2e-16 61.1 0.0 1.6e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 ACL95582.1 - 8.1e-10 39.1 0.1 1.5e-09 38.3 0.1 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Helicase_C_2 PF13307.6 ACL95583.1 - 1.1e-13 51.7 0.0 1.9e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD PF00270.29 ACL95583.1 - 0.00011 22.0 0.0 0.0069 16.2 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Sel1 PF08238.12 ACL95585.2 - 2.7e-41 139.1 31.0 1.2e-09 38.5 0.3 7.8 8 0 0 8 8 8 7 Sel1 repeat TPR_7 PF13176.6 ACL95585.2 - 1.1 9.5 6.1 30 5.0 0.3 4.8 5 1 0 5 5 5 0 Tetratricopeptide repeat DEAD_assoc PF08494.11 ACL95586.1 - 2e-47 161.4 0.0 5.7e-47 160.0 0.0 1.8 1 0 0 1 1 1 1 DEAD/H associated DEAD PF00270.29 ACL95586.1 - 3.5e-22 79.0 0.0 6.3e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ACL95586.1 - 4.5e-17 62.4 0.0 1.1e-16 61.1 0.0 1.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ACL95586.1 - 0.0016 18.5 0.0 0.0027 17.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 ACL95586.1 - 0.15 10.7 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Metallophos PF00149.28 ACL95587.1 - 0.0037 17.8 0.0 0.0045 17.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DDE_Tnp_1_2 PF13586.6 ACL95588.1 - 1.6e-20 73.3 0.2 2.4e-20 72.7 0.2 1.3 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 ACL95588.1 - 1.6e-18 67.2 2.7 5.7e-17 62.1 2.7 2.0 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 ACL95588.1 - 1.9e-08 34.5 0.0 2.3e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 ACL95588.1 - 2.1e-05 24.3 0.0 2.4e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3429 PF11911.8 ACL95589.1 - 6.3e-21 75.2 11.5 7.8e-21 74.9 11.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) FA_desaturase PF00487.24 ACL95589.1 - 0.28 11.0 6.5 0.56 10.0 6.5 1.4 1 1 0 1 1 1 0 Fatty acid desaturase Sel1 PF08238.12 ACL95590.1 - 8.6e-26 89.8 6.9 1.1e-07 32.3 0.1 5.8 5 0 0 5 5 5 3 Sel1 repeat PG_binding_1 PF01471.18 ACL95590.1 - 3.1e-15 56.1 0.0 1.7e-14 53.8 0.0 2.4 1 0 0 1 1 1 1 Putative peptidoglycan binding domain PG_binding_2 PF08823.11 ACL95590.1 - 0.001 19.4 0.3 0.023 15.0 0.0 3.1 3 0 0 3 3 3 1 Putative peptidoglycan binding domain GldM_N PF12081.8 ACL95590.1 - 0.0046 17.1 0.3 0.0046 17.1 0.3 2.4 3 0 0 3 3 3 1 GldM N-terminal domain BAR PF03114.18 ACL95590.1 - 0.028 14.1 4.6 0.14 11.8 1.2 2.4 1 1 1 2 2 2 0 BAR domain CLZ PF16526.5 ACL95590.1 - 0.13 12.7 0.1 0.13 12.7 0.1 6.1 6 2 0 6 6 6 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HAMP PF00672.25 ACL95590.1 - 0.37 11.2 0.0 0.37 11.2 0.0 3.7 4 0 0 4 4 4 0 HAMP domain Baculo_PEP_C PF04513.12 ACL95590.1 - 0.55 10.3 5.2 27 4.8 0.1 4.3 1 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 ACL95590.1 - 0.81 9.8 7.9 14 5.7 1.5 3.8 1 1 3 4 4 4 0 Apolipophorin-III precursor (apoLp-III) BLOC1_2 PF10046.9 ACL95590.1 - 1.8 9.0 8.0 8.4 6.8 2.3 3.5 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Apolipoprotein PF01442.18 ACL95590.1 - 3.1 7.6 60.2 0.17 11.8 15.1 4.5 2 1 2 4 4 4 0 Apolipoprotein A1/A4/E domain DUF4131 PF13567.6 ACL95591.1 - 0.18 11.5 2.8 0.21 11.2 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Wzy_C PF04932.15 ACL95591.1 - 0.7 9.5 3.4 0.82 9.3 3.4 1.1 1 0 0 1 1 1 0 O-Antigen ligase DUF2156 PF09924.9 ACL95592.1 - 1.4e-86 290.2 0.2 1.7e-86 289.9 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) Acetyltransf_6 PF13480.7 ACL95592.1 - 0.0013 18.9 0.3 0.0086 16.2 0.3 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acyl-CoA_dh_M PF02770.19 ACL95593.1 - 7.2e-20 71.0 0.0 2.4e-19 69.3 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ACL95593.1 - 3.1e-19 69.7 0.1 8.2e-19 68.3 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 ACL95593.1 - 1.9e-16 60.6 1.5 2.9e-16 60.0 1.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF1860 PF08949.10 ACL95593.1 - 0.024 14.4 0.1 0.038 13.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1860) Acyl-CoA_dh_1 PF00441.24 ACL95594.1 - 3.6e-27 95.4 4.1 3.6e-27 95.4 4.1 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ACL95594.1 - 2.6e-22 79.6 0.3 2.6e-22 79.6 0.3 2.4 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ACL95594.1 - 4.4e-10 39.6 0.0 1.2e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ACL95594.1 - 2e-08 34.6 5.6 5e-08 33.3 5.6 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PK PF00224.21 ACL95595.1 - 1.6e-106 356.2 0.0 2e-106 355.8 0.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 ACL95595.1 - 2.3e-23 82.6 0.1 7.9e-23 80.9 0.0 1.9 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain IMPDH PF00478.25 ACL95595.1 - 0.021 13.9 0.2 0.17 10.9 0.0 2.1 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Asparaginase_C PF17763.1 ACL95595.1 - 0.11 12.7 0.0 0.39 11.0 0.0 2.0 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain Glyco_hydro_3 PF00933.21 ACL95596.1 - 9.6e-78 261.8 0.0 1.3e-77 261.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Exop_C PF18559.1 ACL95596.1 - 9.7e-43 145.7 0.0 2e-42 144.7 0.0 1.5 1 0 0 1 1 1 1 Galactose-binding domain-like Glyco_hydro_3_C PF01915.22 ACL95596.1 - 1.3e-34 119.9 0.0 2.1e-34 119.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain TMEM125 PF15109.6 ACL95596.1 - 0.018 15.3 0.1 2.2 8.6 0.0 2.4 2 0 0 2 2 2 0 TMEM125 protein family Peripla_BP_3 PF13377.6 ACL95597.1 - 5.1e-40 137.5 0.4 2.1e-39 135.5 0.1 2.0 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 ACL95597.1 - 1.2e-29 103.6 0.0 1.7e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 ACL95597.1 - 1.7e-18 66.2 0.7 3.1e-18 65.3 0.7 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 ACL95597.1 - 4.5e-14 52.7 0.0 6.6e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain HTH_Tnp_ISL3 PF13542.6 ACL95597.1 - 0.0057 16.0 0.3 0.064 12.7 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 TnsD PF15978.5 ACL95597.1 - 0.016 14.3 0.1 0.02 13.9 0.1 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D HTH_23 PF13384.6 ACL95597.1 - 0.024 14.4 0.0 0.073 12.9 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_3 PF01381.22 ACL95597.1 - 0.14 12.2 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix HTH_24 PF13412.6 ACL95597.1 - 0.21 11.2 0.1 0.58 9.8 0.1 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Glucokinase PF02685.16 ACL95598.1 - 3.7e-112 374.4 0.0 4.1e-112 374.3 0.0 1.0 1 0 0 1 1 1 1 Glucokinase ROK PF00480.20 ACL95598.1 - 0.0033 16.9 0.8 0.083 12.4 0.8 2.2 2 0 0 2 2 2 1 ROK family ILVD_EDD PF00920.21 ACL95599.1 - 9.1e-162 539.3 0.3 1e-161 539.1 0.3 1.0 1 0 0 1 1 1 1 Dehydratase family zf-A20 PF01754.16 ACL95599.1 - 0.55 10.2 1.7 0.99 9.4 1.7 1.4 1 0 0 1 1 1 0 A20-like zinc finger Glucosamine_iso PF01182.20 ACL95600.1 - 1.8e-45 155.6 0.0 1.9e-45 155.5 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase G6PD_C PF02781.16 ACL95601.1 - 8.2e-111 369.8 0.0 1e-110 369.5 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 ACL95601.1 - 3.3e-50 171.2 0.0 5e-50 170.6 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain TPR_2 PF07719.17 ACL95602.1 - 0.0007 19.5 17.0 0.093 12.9 0.1 7.0 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 ACL95602.1 - 0.00097 19.6 34.9 0.0065 16.9 0.4 6.9 6 2 0 7 7 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 ACL95602.1 - 0.0014 18.5 4.2 0.082 13.0 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 ACL95602.1 - 0.004 16.9 1.5 1.2 9.1 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ACL95602.1 - 0.0078 16.4 0.0 6.3 7.1 0.0 3.5 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 ACL95602.1 - 0.012 16.2 1.7 0.012 16.2 1.7 9.0 7 2 4 11 11 9 0 Tetratricopeptide repeat TPR_8 PF13181.6 ACL95602.1 - 0.022 14.9 1.0 1 9.7 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 ACL95602.1 - 0.033 14.5 17.3 0.15 12.4 0.2 6.0 5 3 2 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 ACL95602.1 - 0.053 13.4 4.4 2.7 8.0 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 ACL95602.1 - 0.058 13.1 0.1 0.44 10.3 0.0 2.5 2 0 0 2 2 2 0 TPR repeat ParD_antitoxin PF03693.14 ACL95602.1 - 0.058 13.8 0.3 0.15 12.5 0.3 1.6 1 0 0 1 1 1 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH TPR_17 PF13431.6 ACL95602.1 - 0.41 11.1 1.5 1.4e+02 3.2 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 ACL95602.1 - 0.49 11.2 0.1 0.49 11.2 0.1 7.7 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 ACL95602.1 - 1.4 9.9 37.8 0.16 12.8 0.5 8.5 7 1 2 9 9 8 0 Tetratricopeptide repeat MgtE_N PF03448.17 ACL95603.1 - 0.0009 19.8 0.2 0.0016 19.0 0.2 1.4 1 0 0 1 1 1 1 MgtE intracellular N domain DUF3552 PF12072.8 ACL95603.1 - 0.013 14.9 1.4 0.02 14.3 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) MerR-DNA-bind PF09278.11 ACL95603.1 - 0.68 10.5 6.5 0.62 10.6 4.8 1.8 2 0 0 2 2 2 0 MerR, DNA binding TolA_bind_tri PF16331.5 ACL95604.1 - 0.018 15.1 0.4 0.033 14.3 0.4 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF4200 PF13863.6 ACL95604.1 - 0.12 12.7 0.4 0.22 11.9 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) FliM PF02154.15 ACL95605.1 - 3.3e-74 248.9 0.1 4.4e-74 248.5 0.1 1.2 1 0 0 1 1 1 1 Flagellar motor switch protein FliM FliMN_C PF01052.20 ACL95605.1 - 7.1e-17 61.2 0.0 1.5e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Type III flagellar switch regulator (C-ring) FliN C-term FliL PF03748.14 ACL95606.1 - 1.2e-17 64.4 0.1 2e-17 63.6 0.1 1.3 1 0 0 1 1 1 1 Flagellar basal body-associated protein FliL DUF4366 PF14283.6 ACL95606.1 - 0.06 13.4 0.1 0.06 13.4 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) Flg_bbr_C PF06429.13 ACL95607.1 - 3.1e-20 72.1 0.5 9.3e-20 70.6 0.5 1.8 1 0 0 1 1 1 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 ACL95607.1 - 1.8e-12 46.9 0.2 3.3e-12 46.1 0.2 1.5 1 0 0 1 1 1 1 Flagella basal body rod protein Flg_bbr_C PF06429.13 ACL95608.1 - 4.9e-25 87.5 1.5 8.7e-25 86.7 0.4 2.0 2 0 0 2 2 2 1 Flagellar basal body rod FlgEFG protein C-terminal Flg_bb_rod PF00460.20 ACL95608.1 - 3.9e-14 52.2 3.4 3.9e-14 52.2 3.4 2.8 3 0 0 3 3 3 1 Flagella basal body rod protein ChapFlgA PF13144.6 ACL95609.1 - 6.7e-25 87.5 0.9 3.1e-24 85.4 0.2 2.0 2 0 0 2 2 2 1 Chaperone for flagella basal body P-ring formation SAF PF08666.12 ACL95609.1 - 8.2e-09 36.0 4.7 8.5e-09 35.9 0.3 2.9 2 1 1 3 3 3 1 SAF domain FlgH PF02107.16 ACL95610.1 - 2.8e-54 183.2 1.2 3.3e-54 183.0 1.2 1.0 1 0 0 1 1 1 1 Flagellar L-ring protein LPAM_1 PF08139.12 ACL95610.1 - 3.3 8.4 5.3 0.3 11.7 0.6 1.7 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site DUF2649 PF10854.8 ACL95612.1 - 0.11 12.9 2.1 0.18 12.1 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2649) DXP_synthase_N PF13292.6 ACL95614.1 - 2.4e-116 387.7 0.0 4.2e-116 386.9 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 ACL95614.1 - 2.1e-36 125.3 0.2 3.9e-36 124.4 0.2 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ACL95614.1 - 1.1e-29 102.8 0.0 4e-29 101.0 0.0 2.0 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transketolase_N PF00456.21 ACL95614.1 - 2.6e-10 39.8 1.1 0.0023 17.0 0.0 3.2 3 0 0 3 3 3 3 Transketolase, thiamine diphosphate binding domain TPP_enzyme_C PF02775.21 ACL95614.1 - 1.6e-05 24.7 0.1 7.8e-05 22.5 0.2 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 ACL95614.1 - 4.4e-05 22.6 0.1 0.0006 18.9 0.1 2.2 2 0 0 2 2 2 1 Dehydrogenase E1 component polyprenyl_synt PF00348.17 ACL95615.1 - 6.9e-50 169.5 0.1 8.5e-50 169.2 0.1 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Exonuc_VII_S PF02609.16 ACL95616.1 - 6.9e-19 67.7 5.1 8.2e-19 67.4 5.1 1.1 1 0 0 1 1 1 1 Exonuclease VII small subunit TelA PF05816.11 ACL95616.1 - 0.035 13.2 0.0 0.037 13.1 0.0 1.1 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) His_Phos_1 PF00300.22 ACL95617.1 - 5.8e-09 35.9 0.2 1.7e-08 34.4 0.2 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Hist_deacetyl PF00850.19 ACL95618.1 - 1.4e-75 254.6 0.0 1.8e-75 254.2 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Acetyltransf_1 PF00583.25 ACL95619.1 - 4.2e-13 49.6 0.0 5.4e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ACL95619.1 - 2.2e-08 34.1 0.0 3.3e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ACL95619.1 - 8.8e-08 32.5 0.0 1.3e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ACL95619.1 - 8.7e-07 29.7 0.0 1.1e-06 29.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ACL95619.1 - 0.00038 20.4 0.0 0.00062 19.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 ACL95619.1 - 0.0065 16.6 0.0 0.0081 16.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain VWA_CoxE PF05762.14 ACL95620.1 - 7.6e-08 32.0 0.0 3.3e-06 26.7 0.0 2.3 2 0 0 2 2 2 2 VWA domain containing CoxE-like protein HemolysinCabind PF00353.19 ACL95621.1 - 2.9e-05 23.9 7.9 2.9e-05 23.9 7.9 3.8 4 0 0 4 4 4 2 RTX calcium-binding nonapeptide repeat (4 copies) CclA_1 PF16942.5 ACL95621.1 - 0.22 11.8 0.1 0.22 11.8 0.1 2.0 2 0 0 2 2 2 0 Putative cyclic bacteriocin HTH_31 PF13560.6 ACL95622.1 - 2.1e-09 37.6 1.3 4.3e-09 36.6 1.3 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 ACL95622.1 - 6.3e-07 29.4 0.1 1.3e-06 28.3 0.1 1.7 1 1 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 ACL95622.1 - 7.1e-07 29.2 0.0 1.1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 ACL95622.1 - 6.9e-05 22.6 0.0 0.0016 18.3 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.6 ACL95622.1 - 0.0089 15.6 0.1 0.021 14.4 0.1 1.6 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_29 PF13551.6 ACL95622.1 - 0.024 14.7 0.1 4.4 7.4 0.0 2.6 2 1 1 3 3 3 0 Winged helix-turn helix Raf1_HTH PF18579.1 ACL95622.1 - 0.055 13.2 0.3 0.18 11.6 0.3 1.8 1 1 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain Glycos_transf_2 PF00535.26 ACL95623.1 - 1.8e-16 60.4 0.0 2.6e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ACL95623.1 - 8.4e-15 55.3 0.0 1.7e-14 54.3 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 ACL95623.1 - 2e-06 27.5 0.0 0.0013 18.3 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ACL95623.1 - 0.0069 16.3 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_7C PF02709.14 ACL95623.1 - 0.021 14.5 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase Glyco_transf_21 PF13506.6 ACL95623.1 - 0.1 12.1 0.0 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 21 NTP_transf_3 PF12804.7 ACL95623.1 - 0.1 12.9 6.2 0.21 11.9 6.2 1.6 1 1 0 1 1 1 0 MobA-like NTP transferase domain CBM32 PF18344.1 ACL95624.1 - 0.18 11.7 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding module family 32 TetR_C_30 PF17939.1 ACL95626.1 - 1.6e-28 99.2 1.7 2.3e-28 98.7 1.0 1.6 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ACL95626.1 - 4.5e-15 55.2 0.2 9.8e-15 54.1 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family Zea_mays_MuDR PF05928.11 ACL95626.1 - 0.1 12.3 0.3 0.15 11.7 0.3 1.2 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) ELFV_dehydrog_N PF02812.18 ACL95629.1 - 8.9e-23 80.6 0.0 1.7e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 ACL95629.1 - 1.4e-17 64.3 0.5 8.7e-10 38.7 0.0 2.1 1 1 1 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 ACL95629.1 - 5.2e-05 22.7 0.0 9.2e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 ACL95629.1 - 0.0024 17.5 0.1 0.09 12.3 0.1 2.2 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 ACL95629.1 - 0.0024 18.4 0.2 0.011 16.2 0.4 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent adh_short_C2 PF13561.6 ACL95629.1 - 0.0068 16.0 1.0 0.013 15.1 1.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase AdoHcyase_NAD PF00670.21 ACL95629.1 - 0.007 16.4 0.6 0.013 15.6 0.6 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TrkA_N PF02254.18 ACL95629.1 - 0.014 15.6 0.3 0.028 14.7 0.3 1.5 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 ACL95629.1 - 0.019 14.6 0.2 0.028 14.0 0.2 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 ACL95629.1 - 0.019 14.6 0.3 0.034 13.7 0.3 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 ACL95629.1 - 0.05 13.8 0.1 0.099 12.8 0.1 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.21 ACL95629.1 - 0.081 12.3 0.4 0.13 11.6 0.4 1.2 1 0 0 1 1 1 0 ThiF family 3HCDH_N PF02737.18 ACL95629.1 - 0.2 11.5 0.8 0.33 10.8 0.8 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Hydrolase_4 PF12146.8 ACL95630.1 - 7.3e-54 182.6 0.0 9.6e-54 182.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ACL95630.1 - 7.7e-11 42.1 0.0 1.7e-09 37.7 0.1 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ACL95630.1 - 1.3e-07 32.5 17.8 3.3e-07 31.1 17.8 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 ACL95630.1 - 0.012 15.2 0.1 0.017 14.8 0.1 1.3 1 0 0 1 1 1 0 Putative esterase Lipase_GDSL_2 PF13472.6 ACL95630.1 - 0.02 15.3 0.0 0.051 14.0 0.0 1.6 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Lipase_3 PF01764.25 ACL95630.1 - 0.061 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.13 ACL95630.1 - 0.074 12.9 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.12 ACL95630.1 - 0.17 10.5 1.5 7.5 5.1 0.1 2.2 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) UDG PF03167.19 ACL95631.1 - 1.2e-24 87.1 0.0 1.6e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily GST_N_3 PF13417.6 ACL95632.1 - 1.5e-16 60.5 0.0 2.8e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ACL95632.1 - 8.1e-10 38.8 0.0 1.3e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ACL95632.1 - 9.4e-10 38.7 0.0 1.7e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ACL95632.1 - 1e-08 35.4 0.0 2e-08 34.5 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ACL95632.1 - 1.3e-07 31.8 0.0 1.8e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ACL95632.1 - 5.5e-05 23.1 0.2 0.00013 21.9 0.2 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 ACL95632.1 - 0.014 16.2 0.0 0.023 15.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain 4HBT PF03061.22 ACL95634.1 - 1.1e-14 54.5 0.2 1.8e-14 53.9 0.2 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 ACL95634.1 - 0.0041 17.4 0.1 0.0051 17.1 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily GST_N_3 PF13417.6 ACL95635.1 - 1.6e-17 63.6 0.0 2.9e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ACL95635.1 - 3.4e-14 52.9 0.0 6.5e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ACL95635.1 - 6.1e-13 48.9 0.0 1.2e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ACL95635.1 - 1.2e-10 41.4 0.0 2e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ACL95635.1 - 6.7e-06 26.0 0.0 2e-05 24.5 0.0 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ACL95635.1 - 0.0021 18.2 0.0 0.0035 17.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain LytTR PF04397.15 ACL95635.1 - 0.038 14.2 0.0 0.06 13.6 0.0 1.3 1 0 0 1 1 1 0 LytTr DNA-binding domain Inhibitor_G39P PF11417.8 ACL95635.1 - 0.13 12.8 0.1 0.45 11.1 0.0 1.8 2 0 0 2 2 2 0 Loader and inhibitor of phage G40P Nucleos_tra2_C PF07662.13 ACL95636.1 - 4.8e-64 216.0 3.4 4.8e-64 216.0 3.4 2.1 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 ACL95636.1 - 1.6e-17 63.9 4.5 1.6e-17 63.9 4.5 3.4 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 ACL95636.1 - 2.1e-06 28.0 4.2 2.1e-06 28.0 4.2 3.3 3 0 0 3 3 3 1 Nucleoside recognition FtsX PF02687.21 ACL95637.2 - 0.00027 21.4 6.4 0.00027 21.4 6.4 2.9 3 0 0 3 3 3 1 FtsX-like permease family CDC48_N PF02359.18 ACL95637.2 - 0.015 15.5 0.1 0.043 14.0 0.1 1.7 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain DUF3341 PF11821.8 ACL95637.2 - 0.87 9.2 6.4 4.2 7.0 4.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) ABC_tran PF00005.27 ACL95638.1 - 9e-32 110.5 0.0 1.2e-31 110.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ACL95638.1 - 1.2e-10 41.3 0.0 1.1e-09 38.1 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ACL95638.1 - 1.4e-07 31.7 0.0 0.013 15.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ACL95638.1 - 3.1e-07 30.0 0.2 5.9e-07 29.1 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 ACL95638.1 - 0.00011 22.6 0.1 0.0002 21.8 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 ACL95638.1 - 0.00023 21.1 0.0 0.00042 20.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 ACL95638.1 - 0.00038 20.3 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 ACL95638.1 - 0.00074 20.1 0.0 0.0012 19.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ACL95638.1 - 0.0015 18.8 0.0 0.0042 17.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 ACL95638.1 - 0.0027 17.1 0.0 0.0059 16.0 0.0 1.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_27 PF13514.6 ACL95638.1 - 0.0028 17.3 0.0 0.0053 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ACL95638.1 - 0.0051 17.0 1.0 0.019 15.1 1.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ACL95638.1 - 0.0059 16.3 0.2 0.033 13.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 ACL95638.1 - 0.0086 15.7 0.9 0.088 12.4 0.1 2.3 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 ACL95638.1 - 0.015 15.5 0.1 0.4 11.0 0.0 2.7 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit SRP54 PF00448.22 ACL95638.1 - 0.017 14.8 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 ACL95638.1 - 0.019 14.7 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein T2SSE PF00437.20 ACL95638.1 - 0.033 13.3 0.0 0.056 12.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.29 ACL95638.1 - 0.036 14.5 0.1 0.34 11.3 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 ACL95638.1 - 0.037 13.8 0.1 0.054 13.3 0.1 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 ACL95638.1 - 0.044 14.3 0.0 0.15 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ACL95638.1 - 0.081 12.8 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Rad17 PF03215.15 ACL95638.1 - 0.093 12.6 0.0 0.26 11.2 0.0 1.6 2 0 0 2 2 2 0 Rad17 P-loop domain ABC_ATPase PF09818.9 ACL95638.1 - 0.096 11.5 0.1 0.73 8.6 0.1 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_5 PF07728.14 ACL95638.1 - 0.097 12.7 0.1 0.24 11.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 ACL95638.1 - 0.11 12.6 0.1 0.34 11.0 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 ACL95638.1 - 0.14 12.0 0.0 0.57 10.1 0.0 1.9 2 0 0 2 2 2 0 NTPase CbiA PF01656.23 ACL95638.1 - 0.16 12.0 0.1 0.32 11.1 0.1 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_7 PF12775.7 ACL95638.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 ACL95638.1 - 0.18 11.5 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_PrkA PF08298.11 ACL95638.1 - 0.27 10.1 0.0 0.43 9.4 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain HlyD_D23 PF16576.5 ACL95639.1 - 2e-11 43.5 7.3 8e-11 41.6 7.3 1.8 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 ACL95639.1 - 2.4e-11 44.3 7.1 8.5e-07 29.6 0.6 3.3 2 2 1 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 ACL95639.1 - 3.6e-06 26.7 5.0 3.6e-06 26.7 5.0 4.1 4 1 0 4 4 4 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 ACL95639.1 - 0.00026 20.8 0.1 0.0012 18.7 0.1 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme HTH_18 PF12833.7 ACL95639.1 - 0.0013 19.0 0.9 0.0025 18.0 0.9 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Peptidase_M23 PF01551.22 ACL95639.1 - 0.036 14.3 0.1 1.6 9.0 0.1 2.6 2 0 0 2 2 2 0 Peptidase family M23 LptF_LptG PF03739.14 ACL95639.1 - 0.037 12.9 0.1 0.045 12.6 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG SHR3_chaperone PF08229.11 ACL95639.1 - 0.055 12.4 0.8 0.096 11.7 0.1 1.6 2 0 0 2 2 2 0 ER membrane protein SH3 DUF4131 PF13567.6 ACL95639.1 - 0.24 11.1 1.9 1.8 8.2 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) HemX PF04375.14 ACL95639.1 - 5.5 6.2 19.1 3.3 6.9 7.5 2.1 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase adh_short PF00106.25 ACL95643.1 - 1.3e-42 145.5 5.5 2.1e-42 144.8 5.5 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ACL95643.1 - 8.7e-32 110.5 3.9 2.7e-31 108.9 3.9 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ACL95643.1 - 1.4e-19 70.7 2.1 2.1e-19 70.2 2.1 1.2 1 0 0 1 1 1 1 KR domain bPH_5 PF10882.8 ACL95643.1 - 0.11 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial PH domain Toluene_X PF03349.16 ACL95644.1 - 1.2e-126 422.8 10.4 1.4e-126 422.5 10.4 1.0 1 0 0 1 1 1 1 Outer membrane protein transport protein (OMPP1/FadL/TodX) OMP_b-brl PF13505.6 ACL95644.1 - 1.4e-09 38.3 12.8 8.4e-06 26.0 1.1 3.0 2 1 1 3 3 3 2 Outer membrane protein beta-barrel domain DUF3575 PF12099.8 ACL95644.1 - 9.5e-07 28.3 0.1 0.042 13.2 0.0 3.4 2 1 1 3 3 3 2 Protein of unknown function (DUF3575) TonB_dep_Rec PF00593.24 ACL95644.1 - 5.1e-06 26.6 10.6 0.00021 21.3 9.3 2.3 1 1 1 2 2 2 1 TonB dependent receptor BBP2 PF07642.11 ACL95644.1 - 0.00011 21.5 3.2 0.0024 17.1 1.4 2.7 1 1 2 3 3 3 3 Putative beta-barrel porin-2, OmpL-like. bbp2 Porin_4 PF13609.6 ACL95644.1 - 0.00041 20.2 9.5 0.00041 20.2 9.5 3.1 2 1 1 3 3 3 1 Gram-negative porin Opacity PF02462.15 ACL95644.1 - 0.0024 18.0 0.3 37 4.4 0.0 4.2 4 0 0 4 4 4 0 Opacity family porin protein Porin_2 PF02530.14 ACL95644.1 - 0.0028 17.0 1.0 0.012 15.0 0.1 2.1 2 0 0 2 2 2 1 Porin subfamily BBP2_2 PF10082.9 ACL95644.1 - 0.0028 16.6 0.2 0.011 14.6 0.0 2.0 2 0 0 2 2 2 1 Putative beta-barrel porin 2 MipA PF06629.12 ACL95644.1 - 0.0088 16.3 7.0 0.022 15.0 0.5 3.1 1 1 0 2 2 2 1 MltA-interacting protein MipA DUF2490 PF10677.9 ACL95644.1 - 0.018 15.0 0.4 21 5.0 0.0 3.8 3 2 0 3 3 3 0 Protein of unknown function (DUF2490) ParA PF10609.9 ACL95645.1 - 1.7e-92 309.3 0.1 2.2e-92 309.0 0.1 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 ACL95645.1 - 2.6e-14 53.4 0.0 5.4e-14 52.4 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain FeS_assembly_P PF01883.19 ACL95645.1 - 1.2e-13 51.0 1.0 1.2e-13 51.0 1.0 2.1 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein AAA_31 PF13614.6 ACL95645.1 - 2.8e-09 37.2 0.1 6.8e-09 35.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 ACL95645.1 - 1.5e-07 31.0 0.2 2.3e-07 30.4 0.2 1.4 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 ACL95645.1 - 2e-05 23.9 3.4 6.1e-05 22.4 0.9 2.6 3 1 1 4 4 4 1 Anion-transporting ATPase Fer4_NifH PF00142.18 ACL95645.1 - 0.00036 20.1 0.1 0.00059 19.4 0.1 1.3 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 ACL95645.1 - 0.0055 16.3 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain VirC1 PF07015.11 ACL95645.1 - 0.01 15.1 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 0 VirC1 protein MeaB PF03308.16 ACL95645.1 - 0.018 14.0 0.4 0.036 13.1 0.2 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_26 PF13500.6 ACL95645.1 - 0.019 14.8 2.3 17 5.2 0.5 3.2 3 1 0 3 3 3 0 AAA domain SRP54 PF00448.22 ACL95645.1 - 0.032 13.9 0.1 0.066 12.8 0.1 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain CLP1_P PF16575.5 ACL95645.1 - 0.035 13.9 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF834 PF05754.14 ACL95645.1 - 0.036 14.1 2.7 0.088 12.8 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF834) CBP_BcsQ PF06564.12 ACL95645.1 - 0.094 12.2 0.6 0.41 10.1 0.3 1.9 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ APS_kinase PF01583.20 ACL95645.1 - 0.19 11.6 0.1 0.5 10.2 0.0 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase HAD_2 PF13419.6 ACL95646.1 - 2.1e-27 96.4 0.0 3.6e-27 95.6 0.0 1.4 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ACL95646.1 - 1.8e-12 48.0 0.2 2.8e-11 44.1 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ACL95646.1 - 1.3e-06 28.4 0.1 2.6e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 ACL95646.1 - 0.0046 17.4 0.1 0.0064 16.9 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 ACL95646.1 - 0.071 13.2 0.0 4.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Stealth_CR4 PF17103.5 ACL95646.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Stealth protein CR4, conserved region 4 HAD PF12710.7 ACL95647.1 - 1.3e-16 61.6 0.3 2.4e-16 60.7 0.3 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ACL95647.1 - 7.8e-13 49.2 1.4 1.5e-12 48.3 1.4 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ACL95647.1 - 9.7e-08 32.1 1.1 2.4e-07 30.7 0.1 2.0 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 ACL95647.1 - 0.00034 20.1 0.0 0.0047 16.4 0.0 2.0 2 0 0 2 2 2 1 Putative Phosphatase HAD_2 PF13419.6 ACL95647.1 - 0.21 11.7 0.0 16 5.5 0.0 2.6 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase IPPT PF01715.17 ACL95648.2 - 8.3e-65 218.8 0.0 1.1e-64 218.5 0.0 1.0 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 ACL95648.2 - 4.6e-05 22.9 0.0 7.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Isopentenyl transferase AAA_33 PF13671.6 ACL95648.2 - 0.0067 16.6 0.0 0.026 14.7 0.0 1.9 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 ACL95648.2 - 0.012 14.9 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_16 PF13191.6 ACL95648.2 - 0.065 13.6 0.6 0.16 12.4 0.1 1.9 1 1 1 2 2 2 0 AAA ATPase domain CobU PF02283.16 ACL95648.2 - 0.075 12.6 0.0 0.23 11.0 0.0 1.8 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Cytidylate_kin PF02224.18 ACL95648.2 - 0.08 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase CinA PF02464.17 ACL95649.1 - 7.1e-39 132.8 2.8 7.8e-39 132.7 2.8 1.0 1 0 0 1 1 1 1 Competence-damaged protein TPP_enzyme_N PF02776.18 ACL95650.1 - 1.9e-59 200.1 0.1 4e-59 199.1 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 ACL95650.1 - 2.2e-49 167.2 0.0 6.6e-48 162.4 0.0 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 ACL95650.1 - 1.8e-46 157.3 0.0 3.2e-46 156.5 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 ACL95650.1 - 0.0014 18.4 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg ALS_ss_C PF10369.9 ACL95651.1 - 1.5e-24 86.0 0.0 3.6e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 Small subunit of acetolactate synthase ACT PF01842.25 ACL95651.1 - 2.2e-12 46.5 0.2 4.5e-12 45.5 0.2 1.6 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 ACL95651.1 - 4.9e-12 45.5 2.7 8e-12 44.8 0.5 2.1 2 0 0 2 2 2 1 ACT domain ACT_4 PF13291.6 ACL95651.1 - 4.5e-05 23.9 0.3 7.5e-05 23.2 0.3 1.3 1 0 0 1 1 1 1 ACT domain SspB PF04386.13 ACL95652.1 - 3.5e-43 147.2 0.0 4.2e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 Stringent starvation protein B 4HBT PF03061.22 ACL95653.1 - 6e-14 52.1 0.1 8.8e-14 51.6 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 ACL95653.1 - 0.00014 22.3 0.0 0.00032 21.0 0.0 1.5 1 1 0 1 1 1 1 Thioesterase-like superfamily DUF4946 PF16304.5 ACL95653.1 - 0.062 13.0 0.0 0.069 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4946) Peptidase_C13 PF01650.18 ACL95654.1 - 1.1e-12 48.0 0.0 5.3e-12 45.8 0.0 1.8 2 0 0 2 2 2 1 Peptidase C13 family Peptidase_C14 PF00656.22 ACL95654.1 - 0.044 13.7 0.0 0.049 13.6 0.0 1.1 1 0 0 1 1 1 0 Caspase domain Beta-lactamase PF00144.24 ACL95655.1 - 2e-73 247.5 4.8 8.8e-73 245.4 4.8 2.0 1 1 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 ACL95655.1 - 0.0059 16.2 0.1 0.18 11.4 0.1 2.3 1 1 0 1 1 1 1 Beta-lactamase enzyme family DUF3483 PF11982.8 ACL95655.1 - 0.13 11.9 7.2 1.3 8.6 3.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3483) DUF5367 PF17329.2 ACL95656.1 - 9.1e-05 22.5 0.6 0.00013 22.0 0.6 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5367) RusA PF05866.11 ACL95657.1 - 3.8e-12 46.8 0.0 4.7e-12 46.5 0.0 1.3 1 1 0 1 1 1 1 Endodeoxyribonuclease RusA DUF1697 PF08002.11 ACL95658.2 - 1.1e-34 119.8 0.0 1.3e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1697) Lyase_1 PF00206.20 ACL95659.1 - 1e-117 393.0 0.0 1.3e-117 392.7 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 ACL95659.1 - 7.7e-21 74.3 0.1 1.7e-20 73.2 0.1 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus Acetyltransf_10 PF13673.7 ACL95660.1 - 8.9e-11 41.8 0.0 1.1e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ACL95660.1 - 6.9e-09 36.0 0.0 7.8e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ACL95660.1 - 1.4e-07 31.9 0.0 1.6e-07 31.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ACL95660.1 - 0.0012 18.7 0.1 0.0035 17.3 0.0 2.0 2 1 0 2 2 2 1 FR47-like protein PanZ PF12568.8 ACL95660.1 - 0.062 13.0 0.0 0.077 12.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_13 PF13880.6 ACL95660.1 - 0.088 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase YccF PF03733.13 ACL95661.1 - 2.8e-30 104.8 30.7 2.6e-15 56.9 5.8 2.1 2 0 0 2 2 2 2 Inner membrane component domain DUF3930 PF13067.6 ACL95661.1 - 0.001 19.3 1.7 0.025 14.8 0.2 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3930) DUF1270 PF06900.11 ACL95661.1 - 0.0087 16.4 0.7 0.022 15.1 0.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1270) polyprenyl_synt PF00348.17 ACL95663.2 - 1.6e-70 237.1 0.0 1.9e-70 236.9 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase MTS PF05175.14 ACL95664.1 - 5.9e-08 32.4 0.0 9.2e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain N6_Mtase PF02384.16 ACL95664.1 - 8.6e-08 31.8 0.0 1.2e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_31 PF13847.6 ACL95664.1 - 9.2e-08 32.0 0.0 1.1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 ACL95664.1 - 6.2e-06 26.0 0.0 9.5e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 ACL95664.1 - 9.5e-05 23.0 0.0 0.00017 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 ACL95664.1 - 0.00082 19.1 0.7 0.0054 16.4 0.7 1.9 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.13 ACL95664.1 - 0.0023 17.4 0.1 0.0034 16.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 ACL95664.1 - 0.0098 15.4 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_15 PF09445.10 ACL95664.1 - 0.0098 15.5 0.0 0.013 15.0 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.12 ACL95664.1 - 0.011 16.3 0.0 0.023 15.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 ACL95664.1 - 0.013 15.2 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cytochrom_C PF00034.21 ACL95665.1 - 8.5e-09 36.4 0.0 2.4e-07 31.8 0.0 2.1 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 ACL95665.1 - 3.6e-08 33.6 0.0 5.4e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 ACL95665.1 - 0.11 12.2 0.0 1.8 8.2 0.0 2.0 2 0 0 2 2 2 0 Cytochrome c-550 domain Cytochrom_C1 PF02167.15 ACL95665.1 - 0.15 11.8 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C1 family Nuc_deoxyrib_tr PF05014.15 ACL95666.1 - 2.5e-34 118.1 0.0 3e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase CAP PF00188.26 ACL95667.1 - 8.2e-15 55.8 0.0 1.1e-14 55.3 0.0 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family TAT_signal PF10518.9 ACL95667.1 - 0.33 10.8 5.1 0.86 9.6 5.1 1.8 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence YceI PF04264.13 ACL95668.1 - 1.2e-37 129.7 2.1 1.4e-37 129.5 2.1 1.0 1 0 0 1 1 1 1 YceI-like domain PSI_PSAK PF01241.18 ACL95668.1 - 0.006 16.6 0.0 0.022 14.8 0.0 2.0 2 0 0 2 2 2 1 Photosystem I psaG / psaK Fusion_gly PF00523.18 ACL95668.1 - 0.97 7.6 6.2 0.21 9.8 0.7 2.0 2 0 0 2 2 2 0 Fusion glycoprotein F0 IlvN PF07991.12 ACL95669.1 - 4.7e-72 240.9 0.7 6.4e-72 240.5 0.7 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 ACL95669.1 - 1.6e-66 223.1 0.1 2.1e-66 222.6 0.1 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.19 ACL95669.1 - 7.7e-05 22.1 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 ACL95669.1 - 0.00015 22.2 0.5 0.0003 21.3 0.5 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 ACL95669.1 - 0.0045 17.2 0.1 0.0085 16.3 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.21 ACL95669.1 - 0.034 13.5 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 ThiF family Oxidored_nitro PF00148.19 ACL95669.1 - 0.06 12.1 0.1 0.1 11.3 0.1 1.3 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase AdoHcyase_NAD PF00670.21 ACL95669.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain RcnB PF11776.8 ACL95670.1 - 1.9e-14 53.4 3.7 1.9e-14 53.4 3.7 3.0 2 1 0 2 2 2 1 Nickel/cobalt transporter regulator DUF924 PF06041.11 ACL95671.1 - 1.1e-58 198.4 0.2 1.2e-58 198.2 0.2 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) SH3_3 PF08239.11 ACL95672.1 - 4.6e-05 23.6 0.3 0.00016 21.9 0.1 2.0 2 0 0 2 2 2 1 Bacterial SH3 domain SH3_4 PF06347.13 ACL95672.1 - 0.008 16.0 0.5 0.008 16.0 0.5 1.9 2 0 0 2 2 2 1 Bacterial SH3 domain LpoB PF13036.6 ACL95672.1 - 0.022 14.7 0.5 0.049 13.6 0.1 1.7 2 0 0 2 2 2 0 Peptidoglycan-synthase activator LpoB Thymidylat_synt PF00303.19 ACL95673.1 - 3.5e-123 410.0 0.0 4e-123 409.8 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase ADH_zinc_N_2 PF13602.6 ACL95674.2 - 7.1e-18 65.9 0.1 1.3e-17 65.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ACL95674.2 - 4.3e-10 39.4 0.0 7.5e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ACL95674.2 - 5e-10 39.5 1.4 9.4e-10 38.6 1.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DHFR_1 PF00186.19 ACL95675.1 - 3.3e-52 176.4 0.0 3.7e-52 176.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrofolate reductase DUF3667 PF12412.8 ACL95676.1 - 2.1e-18 65.6 1.1 2.1e-18 65.6 1.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3667) DZR PF12773.7 ACL95676.1 - 0.011 15.7 1.3 0.018 15.0 1.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-NADH-PPase PF09297.11 ACL95676.1 - 0.065 12.9 0.5 0.065 12.9 0.5 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain MscS_porin PF12795.7 ACL95676.1 - 0.094 12.2 8.2 0.13 11.8 8.2 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Wtap PF17098.5 ACL95676.1 - 0.15 12.0 3.5 0.52 10.2 3.5 1.8 1 1 0 1 1 1 0 WTAP/Mum2p family IBR PF01485.21 ACL95676.1 - 0.16 12.2 0.9 0.29 11.4 0.9 1.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Nudix_N_2 PF14803.6 ACL95676.1 - 0.24 11.3 3.8 1.3 9.0 0.1 2.4 2 0 0 2 2 2 0 Nudix N-terminal Spc7 PF08317.11 ACL95676.1 - 0.25 10.2 1.0 0.37 9.6 1.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4148 PF13663.6 ACL95676.1 - 0.48 10.6 5.4 0.25 11.6 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) zf-ribbon_3 PF13248.6 ACL95676.1 - 0.67 9.4 5.8 1.3 8.5 5.8 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 ACL95676.1 - 3.5 7.5 5.4 67 3.4 5.4 2.2 1 1 0 1 1 1 0 zinc-ribbon domain SGL PF08450.12 ACL95677.1 - 3.4e-64 216.8 0.0 4e-64 216.5 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 ACL95677.1 - 0.00027 21.1 0.0 0.002 18.3 0.0 2.3 3 0 0 3 3 3 1 Arylesterase NHL PF01436.21 ACL95677.1 - 0.00053 19.9 3.9 0.19 11.8 0.1 4.4 4 0 0 4 4 4 1 NHL repeat Str_synth PF03088.16 ACL95677.1 - 0.013 15.6 0.0 7.9 6.7 0.0 3.1 3 0 0 3 3 3 0 Strictosidine synthase Oxidored_FMN PF00724.20 ACL95678.1 - 1.8e-66 224.7 0.0 2.5e-65 221.0 0.0 1.9 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family PGA_cap PF09587.10 ACL95678.1 - 0.081 12.4 0.1 0.22 10.9 0.1 1.5 1 1 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap PsiB PF06290.11 ACL95678.1 - 0.17 11.3 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Plasmid SOS inhibition protein (PsiB) DUF346 PF03984.13 ACL95678.1 - 0.79 9.5 3.2 10 6.0 0.8 2.5 2 0 0 2 2 2 0 Repeat of unknown function (DUF346) DUF4282 PF14110.6 ACL95679.1 - 5.3 7.8 7.7 1.7 9.5 1.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4282) Acyl-CoA_dh_1 PF00441.24 ACL95680.1 - 3.8e-20 72.6 0.0 5.6e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ACL95680.1 - 7e-20 71.0 0.0 1.2e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ACL95680.1 - 5.2e-18 65.7 0.0 1.1e-17 64.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 ACL95680.1 - 0.068 12.8 0.0 0.16 11.6 0.0 1.5 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Acyl-CoA_ox_N PF14749.6 ACL95680.1 - 0.12 12.9 0.0 0.21 12.2 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal ABM PF03992.16 ACL95681.1 - 4.7e-18 65.1 0.0 5.4e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF5377 PF17347.2 ACL95681.1 - 0.1 12.9 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5377) Osw5 PF17062.5 ACL95682.1 - 0.032 14.3 2.5 0.046 13.8 2.5 1.3 1 0 0 1 1 1 0 Outer spore wall 5 TerB PF05099.13 ACL95683.2 - 1.2e-28 99.9 0.0 2e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TerB DnaJ PF00226.31 ACL95683.2 - 4.4e-07 29.9 0.0 8.1e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain CCDC53 PF10152.9 ACL95684.3 - 0.94 9.9 4.4 0.53 10.7 1.9 1.7 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex FAP PF07174.11 ACL95684.3 - 1.2 8.5 36.5 0.019 14.4 26.6 2.4 2 1 0 2 2 2 0 Fibronectin-attachment protein (FAP) Glyco_hydro_1 PF00232.18 ACL95685.1 - 6.1e-125 417.2 0.0 7.5e-125 416.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Met_synt_B12 PF02965.17 ACL95686.1 - 6e-119 396.5 0.0 1e-118 395.8 0.0 1.4 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain Pterin_bind PF00809.22 ACL95686.1 - 9.9e-60 202.2 0.4 3.2e-59 200.6 0.4 1.9 2 0 0 2 2 2 1 Pterin binding enzyme B12-binding_2 PF02607.17 ACL95686.1 - 1.2e-26 93.0 0.4 6.5e-26 90.6 0.4 2.5 1 0 0 1 1 1 1 B12 binding domain B12-binding PF02310.19 ACL95686.1 - 4.1e-19 68.8 1.0 1e-18 67.5 0.1 2.2 2 0 0 2 2 2 1 B12 binding domain ComA PF02679.15 ACL95686.1 - 0.099 12.1 0.1 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 (2R)-phospho-3-sulfolactate synthase (ComA) S-methyl_trans PF02574.16 ACL95687.1 - 7.2e-74 249.0 0.0 8.3e-74 248.8 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Lactamase_B PF00753.27 ACL95688.1 - 6.1e-22 78.6 2.4 1.1e-21 77.7 2.4 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ACL95688.1 - 0.00019 21.0 0.1 0.00027 20.5 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain MTHFR PF02219.17 ACL95689.1 - 1.9e-91 306.3 0.0 2.4e-91 306.1 0.0 1.0 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Methyltransf_11 PF08241.12 ACL95690.1 - 2.2e-20 73.1 0.0 4.9e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ACL95690.1 - 2.9e-16 59.6 0.0 6.2e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ACL95690.1 - 1.4e-15 57.7 0.1 3.4e-15 56.5 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain HTH_5 PF01022.20 ACL95690.1 - 2e-13 50.0 2.6 4.8e-13 48.8 2.6 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family Methyltransf_12 PF08242.12 ACL95690.1 - 3.2e-12 47.1 0.0 7.9e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ACL95690.1 - 1.9e-11 44.1 0.0 2.9e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain HTH_20 PF12840.7 ACL95690.1 - 5.2e-11 42.5 5.5 6e-11 42.3 3.0 2.5 3 0 0 3 3 2 1 Helix-turn-helix domain MarR_2 PF12802.7 ACL95690.1 - 3.4e-09 36.4 4.1 1.2e-08 34.7 0.6 3.2 3 0 0 3 3 3 1 MarR family Ubie_methyltran PF01209.18 ACL95690.1 - 3e-08 33.3 0.0 4.2e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family HTH_24 PF13412.6 ACL95690.1 - 3.8e-05 23.2 0.5 7.4e-05 22.2 0.5 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Methyltransf_2 PF00891.18 ACL95690.1 - 5.5e-05 22.6 0.0 8.2e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain TrmB PF01978.19 ACL95690.1 - 0.00014 21.7 0.0 0.00042 20.1 0.0 1.8 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_27 PF13463.6 ACL95690.1 - 0.0028 18.1 0.0 0.013 16.0 0.0 2.1 2 0 0 2 2 1 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 ACL95690.1 - 0.0038 17.0 2.5 0.013 15.3 1.5 2.6 2 0 0 2 2 2 1 IclR helix-turn-helix domain MTS PF05175.14 ACL95690.1 - 0.0084 15.7 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain MarR PF01047.22 ACL95690.1 - 0.015 15.2 0.1 0.029 14.3 0.1 1.5 1 0 0 1 1 1 0 MarR family HTH_28 PF13518.6 ACL95690.1 - 0.092 12.9 0.0 0.37 10.9 0.0 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain MetW PF07021.12 ACL95690.1 - 0.098 12.2 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Rsm22 PF09243.10 ACL95690.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Fe_dep_repress PF01325.19 ACL95690.1 - 0.17 12.1 0.0 0.41 10.9 0.0 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_53 PF18606.1 ACL95690.1 - 1.3 8.7 6.5 2.7 7.8 0.1 3.4 2 1 1 3 3 3 0 Zap helix turn helix N-terminal domain Glyoxalase_6 PF18029.1 ACL95691.1 - 1.5e-07 32.1 0.3 1.8e-07 31.9 0.3 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 ACL95691.1 - 0.00037 20.7 0.0 0.0013 18.9 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ACL95691.1 - 0.0018 18.5 0.5 0.24 11.7 0.1 2.8 1 1 2 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily LysR_substrate PF03466.20 ACL95692.2 - 1.9e-16 60.1 9.2 1.9e-16 60.1 9.2 1.6 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 ACL95692.2 - 9.9e-15 54.2 0.1 2.8e-14 52.8 0.2 1.8 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 ACL95692.2 - 0.038 13.9 1.3 0.13 12.2 0.0 2.5 3 0 0 3 3 3 0 MarR family Crp PF00325.20 ACL95692.2 - 0.055 13.1 0.2 0.13 11.9 0.2 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family HTH_24 PF13412.6 ACL95692.2 - 0.15 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding SnoaL_2 PF12680.7 ACL95693.1 - 1.9e-17 63.8 0.6 2.3e-17 63.5 0.6 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 ACL95693.1 - 1.1e-09 38.2 0.1 1.6e-09 37.6 0.1 1.3 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase WI12 PF07107.11 ACL95693.1 - 0.033 14.3 0.0 0.054 13.6 0.0 1.5 1 0 0 1 1 1 0 Wound-induced protein WI12 PHZA_PHZB PF03284.13 ACL95693.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.4 1 1 0 1 1 1 0 Phenazine biosynthesis protein A/B Alpha-amyl_C2 PF07821.12 ACL95693.1 - 0.15 12.4 0.1 0.5 10.6 0.0 1.9 3 0 0 3 3 3 0 Alpha-amylase C-terminal beta-sheet domain 2-Hacid_dh_C PF02826.19 ACL95695.1 - 8.7e-49 165.3 0.0 1.1e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ACL95695.1 - 7.2e-24 84.0 0.0 8.7e-24 83.7 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.6 ACL95695.1 - 0.00015 22.2 0.0 0.00031 21.2 0.0 1.4 1 0 0 1 1 1 1 XdhC Rossmann domain NAD_binding_2 PF03446.15 ACL95695.1 - 0.0016 18.6 0.0 0.0025 18.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.6 ACL95695.1 - 0.049 14.1 0.0 0.099 13.1 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ABC_tran PF00005.27 ACL95696.1 - 1.9e-51 174.1 0.3 3.8e-24 85.7 0.0 2.8 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 ACL95696.1 - 1.4e-17 64.4 1.3 0.00093 19.1 0.1 4.3 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 ACL95696.1 - 8.3e-13 48.2 6.7 3.8e-11 42.9 4.6 2.4 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 ACL95696.1 - 3.8e-11 42.9 1.6 0.064 12.7 0.0 4.3 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ACL95696.1 - 2.4e-07 30.4 0.4 0.0054 16.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ACL95696.1 - 2.1e-06 27.8 0.0 0.026 14.6 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 ACL95696.1 - 7.8e-06 26.5 6.8 0.0012 19.4 0.2 3.2 2 1 1 3 3 3 2 AAA domain AAA_18 PF13238.6 ACL95696.1 - 0.00011 22.7 1.2 1.1 9.8 0.1 3.6 3 1 0 3 3 3 2 AAA domain AAA_22 PF13401.6 ACL95696.1 - 0.00023 21.5 2.5 0.13 12.6 0.1 3.3 2 2 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ACL95696.1 - 0.00028 20.8 0.2 0.14 12.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_15 PF13175.6 ACL95696.1 - 0.0012 18.6 0.2 2.2 7.9 0.1 2.6 2 1 0 2 2 2 2 AAA ATPase domain AAA_13 PF13166.6 ACL95696.1 - 0.0026 16.5 1.1 4.7 5.7 0.0 3.5 3 1 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 ACL95696.1 - 0.0028 17.9 2.4 2.5 8.4 0.0 4.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 ACL95696.1 - 0.0029 17.3 0.8 1.9 8.2 0.1 3.1 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.22 ACL95696.1 - 0.0041 16.3 0.1 2.3 7.3 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 ACL95696.1 - 0.0053 17.2 4.4 4.3 7.7 0.3 3.4 2 1 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 ACL95696.1 - 0.0054 16.9 5.0 1.8 8.7 0.1 3.4 3 1 0 3 3 3 2 AAA domain MeaB PF03308.16 ACL95696.1 - 0.0055 15.7 0.2 0.62 9.0 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_14 PF13173.6 ACL95696.1 - 0.012 15.6 0.0 4.2 7.4 0.0 3.1 4 0 0 4 4 3 0 AAA domain Dynamin_N PF00350.23 ACL95696.1 - 0.022 14.8 6.1 0.54 10.3 0.0 2.8 3 0 0 3 3 3 0 Dynamin family cobW PF02492.19 ACL95696.1 - 0.023 14.3 0.9 5.3 6.6 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 ACL95696.1 - 0.026 14.2 1.8 5.8 6.6 0.1 2.8 3 0 0 3 3 2 0 AAA domain Roc PF08477.13 ACL95696.1 - 0.027 14.7 0.4 15 5.9 0.1 2.8 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_27 PF13514.6 ACL95696.1 - 0.051 13.2 5.2 0.21 11.2 0.0 2.6 3 0 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.17 ACL95696.1 - 0.051 13.4 1.8 9.8 5.9 0.1 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Herpes_UL25 PF01499.16 ACL95696.1 - 0.069 11.7 0.3 0.11 11.0 0.3 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family DLIC PF05783.11 ACL95696.1 - 0.079 11.8 1.8 1.5 7.6 0.0 2.5 3 0 0 3 3 2 0 Dynein light intermediate chain (DLIC) Spore_IV_A PF09547.10 ACL95696.1 - 0.1 11.5 0.3 9.9 5.0 0.0 2.3 2 0 0 2 2 2 0 Stage IV sporulation protein A (spore_IV_A) KAP_NTPase PF07693.14 ACL95696.1 - 0.14 11.4 0.0 2.9 7.0 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain PRK PF00485.18 ACL95696.1 - 0.14 11.9 0.0 19 4.9 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 ACL95696.1 - 0.15 12.5 0.0 21 5.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase ATPase_2 PF01637.18 ACL95696.1 - 0.15 11.9 0.4 14 5.5 0.0 2.6 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea FeoB_N PF02421.18 ACL95696.1 - 0.21 11.1 0.8 7.7 6.0 0.1 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA PF00004.29 ACL95696.1 - 0.74 10.2 2.8 7.7 6.9 0.0 2.9 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 ACL95696.1 - 1.4 9.1 7.2 3 8.1 0.0 3.4 4 0 0 4 4 3 0 AAA domain Zeta_toxin PF06414.12 ACL95696.1 - 1.5 8.1 5.4 17 4.6 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin NACHT PF05729.12 ACL95696.1 - 1.9 8.4 7.1 4.5 7.2 0.2 3.1 4 0 0 4 4 3 0 NACHT domain SRP54 PF00448.22 ACL95696.1 - 3.2 7.3 4.2 11 5.6 0.2 2.9 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain DUF87 PF01935.17 ACL95696.1 - 7.1 6.7 8.5 6.9 6.7 0.7 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain TonB_dep_Rec PF00593.24 ACL95697.1 - 3e-44 152.7 31.8 4.9e-44 152.0 31.8 1.3 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 ACL95697.1 - 9.5e-13 48.7 1.5 2.4e-12 47.4 1.5 1.7 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 ACL95697.1 - 0.00051 19.1 0.4 0.0021 17.1 0.1 1.9 1 1 1 2 2 2 1 Outer membrane protein beta-barrel family DUF560 PF04575.13 ACL95697.1 - 0.031 13.7 0.0 0.069 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF560) Peptidase_S24 PF00717.23 ACL95698.1 - 3.5e-22 78.1 0.0 5.6e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 ACL95698.1 - 2.1e-10 40.5 0.1 0.0009 19.0 0.0 2.6 1 1 0 2 2 2 2 Signal peptidase, peptidase S26 EF-hand_5 PF13202.6 ACL95699.1 - 9.7e-07 28.0 0.0 1.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 ACL95699.1 - 8.3e-05 21.9 0.0 0.00014 21.2 0.0 1.4 1 0 0 1 1 1 1 EF hand MarR_2 PF12802.7 ACL95699.1 - 0.00037 20.3 0.1 0.00075 19.3 0.1 1.5 1 0 0 1 1 1 1 MarR family RskA PF10099.9 ACL95699.1 - 0.00064 20.1 5.9 0.00078 19.8 5.9 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA EF-hand_6 PF13405.6 ACL95699.1 - 0.002 17.9 0.0 0.0037 17.1 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 ACL95699.1 - 0.0025 18.2 0.0 0.0027 18.1 0.0 1.3 1 1 0 1 1 1 1 EF-hand domain pair DUF2613 PF11021.8 ACL95699.1 - 0.003 17.6 1.2 0.005 16.9 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2613) HTH_27 PF13463.6 ACL95699.1 - 0.053 14.0 0.0 0.075 13.5 0.0 1.2 1 0 0 1 1 1 0 Winged helix DNA-binding domain Lipase_GDSL_2 PF13472.6 ACL95700.1 - 5.9e-23 82.2 1.7 5.9e-23 82.2 1.7 1.8 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ACL95700.1 - 1.3e-09 38.4 0.0 1.9e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Polysacc_deac_1 PF01522.21 ACL95701.1 - 1.3e-20 73.5 0.0 2.3e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF4148 PF13663.6 ACL95701.1 - 0.031 14.5 4.3 0.049 13.8 2.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4148) DUF2156 PF09924.9 ACL95701.1 - 0.04 12.9 0.0 1.6 7.7 0.0 2.1 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2156) Peptidase_S66 PF02016.15 ACL95701.1 - 0.073 13.2 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 LD-carboxypeptidase N-terminal domain DPPIV_N PF00930.21 ACL95702.1 - 1e-95 320.5 0.0 2.4e-95 319.3 0.0 1.5 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 ACL95702.1 - 6.4e-54 182.6 0.0 1e-53 182.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 ACL95702.1 - 5.9e-10 39.2 0.1 4.7e-08 32.9 0.1 2.2 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 ACL95702.1 - 1.2e-06 28.2 0.0 5.3e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family PD40 PF07676.12 ACL95702.1 - 2.8e-06 27.1 1.1 8.8 6.4 0.0 5.7 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat Esterase PF00756.20 ACL95702.1 - 0.0014 18.4 0.0 0.0032 17.1 0.0 1.6 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 ACL95702.1 - 0.0022 17.3 0.0 0.59 9.4 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ACL95702.1 - 0.0023 17.6 0.0 0.005 16.5 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 ACL95702.1 - 0.0063 15.2 0.0 0.64 8.6 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 ACL95702.1 - 0.013 15.4 0.0 0.035 14.0 0.0 1.6 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal SGL PF08450.12 ACL95702.1 - 0.017 14.7 0.4 7.3 6.1 0.1 3.8 2 1 1 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region FSH1 PF03959.13 ACL95702.1 - 0.036 13.7 0.0 0.1 12.2 0.0 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 ACL95702.1 - 0.066 13.8 3.5 0.19 12.3 0.1 3.0 2 1 1 3 3 3 0 Alpha/beta hydrolase family FemAB_like PF04339.12 ACL95704.1 - 4.7e-155 516.3 0.0 5.4e-155 516.1 0.0 1.0 1 0 0 1 1 1 1 Peptidogalycan biosysnthesis/recognition Acetyltransf_6 PF13480.7 ACL95704.1 - 5.6e-13 49.3 1.2 5.6e-13 49.3 1.2 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain GDPD PF03009.17 ACL95705.1 - 6.5e-20 71.9 0.0 5.5e-17 62.3 0.0 2.1 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family YjgF_endoribonc PF14588.6 ACL95706.1 - 7.7e-31 107.2 0.0 8.6e-31 107.1 0.0 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 ACL95706.1 - 4.4e-19 68.7 0.0 6.1e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Phasin_2 PF09361.10 ACL95707.1 - 3.6e-22 78.5 13.3 3.6e-22 78.5 13.3 2.1 1 1 1 2 2 2 1 Phasin protein DUF1664 PF07889.12 ACL95707.1 - 0.11 12.6 1.6 4.8 7.2 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 ACL95707.1 - 0.18 11.9 3.6 6.2 6.9 0.7 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2849 PF11011.8 ACL95707.1 - 4.9 7.9 10.2 1.4 9.7 2.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2849) Peptidase_S11 PF00768.20 ACL95708.1 - 4.1e-60 203.2 0.0 6.1e-60 202.7 0.0 1.2 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 ACL95708.1 - 5.8e-11 42.4 0.2 9.3e-11 41.7 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase enzyme family SPOR PF05036.13 ACL95708.1 - 3.6e-10 40.1 0.6 8.7e-10 38.8 0.1 1.9 2 0 0 2 2 2 1 Sporulation related domain Peptidase_S13 PF02113.15 ACL95708.1 - 4.1e-06 25.8 0.1 0.001 17.9 0.0 2.1 1 1 1 2 2 2 2 D-Ala-D-Ala carboxypeptidase 3 (S13) family Aminotran_1_2 PF00155.21 ACL95709.1 - 7.9e-27 94.4 0.0 1.3e-26 93.7 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 ACL95709.1 - 3.2e-09 36.1 0.0 4.3e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DnaJ PF00226.31 ACL95710.1 - 2.1e-06 27.8 0.0 3.3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 ACL95710.1 - 0.00095 19.2 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 Pam16 MipZ PF09140.11 ACL95711.1 - 2.3e-120 400.7 0.0 2.7e-120 400.6 0.0 1.0 1 0 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.6 ACL95711.1 - 2.4e-13 50.4 0.0 2e-08 34.3 0.1 2.2 1 1 1 2 2 2 2 AAA domain CbiA PF01656.23 ACL95711.1 - 5.2e-10 39.5 0.0 7.8e-10 38.9 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 ACL95711.1 - 3.4e-09 36.5 0.0 1.1e-07 31.6 0.0 2.1 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase VirC1 PF07015.11 ACL95711.1 - 0.00021 20.7 0.1 0.0094 15.3 0.1 2.1 1 1 0 1 1 1 1 VirC1 protein CBP_BcsQ PF06564.12 ACL95711.1 - 0.00051 19.6 0.0 0.55 9.7 0.0 2.4 2 0 0 2 2 2 2 Cellulose biosynthesis protein BcsQ LpxK PF02606.14 ACL95711.1 - 0.0019 17.4 0.2 0.0036 16.5 0.2 1.4 1 0 0 1 1 1 1 Tetraacyldisaccharide-1-P 4'-kinase CLP1_P PF16575.5 ACL95711.1 - 0.0062 16.3 0.0 0.016 15.0 0.0 1.6 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MeaB PF03308.16 ACL95711.1 - 0.023 13.7 0.2 0.051 12.6 0.2 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 ACL95711.1 - 0.044 13.3 0.4 0.095 12.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.18 ACL95711.1 - 0.19 11.1 0.0 0.36 10.2 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Pantoate_ligase PF02569.15 ACL95712.1 - 2.9e-96 321.8 0.0 3.3e-96 321.6 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase DUF1489 PF07370.11 ACL95714.1 - 1.9e-48 163.7 0.0 2.1e-48 163.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1489) CPSase_L_D2 PF02786.17 ACL95715.1 - 9.1e-73 244.2 0.1 1.5e-72 243.5 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ACL95715.1 - 2.4e-43 147.2 0.5 6.8e-43 145.7 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ACL95715.1 - 6.3e-35 119.5 0.0 2e-34 117.9 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 ACL95715.1 - 2.4e-16 59.3 0.6 1e-15 57.3 0.6 2.2 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 ACL95715.1 - 3.3e-11 42.8 0.3 3.5e-06 26.8 0.0 2.9 2 1 1 3 3 3 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 ACL95715.1 - 1.7e-09 37.5 0.0 3.7e-09 36.4 0.0 1.4 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 ACL95715.1 - 7e-08 32.2 0.1 1.1e-07 31.5 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 ACL95715.1 - 1.8e-06 28.6 0.8 0.054 14.2 0.0 2.9 3 0 0 3 3 3 2 HlyD family secretion protein HlyD_D23 PF16576.5 ACL95715.1 - 0.00015 21.1 0.4 0.41 9.8 0.1 2.3 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_3 PF02655.14 ACL95715.1 - 0.0076 16.3 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain PASTA PF03793.19 ACL95715.1 - 0.025 14.4 0.2 0.086 12.7 0.2 1.9 1 0 0 1 1 1 0 PASTA domain ATP-grasp_4 PF13535.6 ACL95715.1 - 0.054 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain LAL_C2 PF18603.1 ACL95715.1 - 0.056 13.6 3.8 0.059 13.5 0.0 3.0 3 0 0 3 3 2 0 L-amino acid ligase C-terminal domain 2 GCV_H PF01597.19 ACL95715.1 - 0.056 13.3 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein Trp_ring PF18669.1 ACL95715.1 - 0.21 11.8 1.3 0.41 10.9 0.3 2.0 2 0 0 2 2 1 0 Trimeric autotransporter adhesin Trp ring domain ECH_1 PF00378.20 ACL95716.1 - 1.9e-38 132.3 0.0 2.1e-38 132.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ACL95716.1 - 1.4e-24 87.2 0.1 6.3e-24 85.1 0.0 1.7 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Carboxyl_trans PF01039.22 ACL95717.1 - 8.7e-151 502.9 0.0 1.1e-150 502.6 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain Patatin PF01734.22 ACL95718.2 - 2.7e-24 86.5 3.1 6.9e-24 85.2 1.5 2.5 2 1 0 2 2 2 1 Patatin-like phospholipase cNMP_binding PF00027.29 ACL95718.2 - 2.5e-19 69.1 0.0 5.5e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Acyl-CoA_dh_1 PF00441.24 ACL95719.1 - 1.4e-44 151.9 0.4 1.4e-44 151.9 0.4 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ACL95719.1 - 3.1e-36 124.5 0.0 8.3e-36 123.1 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ACL95719.1 - 3.6e-27 94.4 0.1 6.8e-27 93.5 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ACL95719.1 - 2.2e-16 60.3 1.5 2.2e-16 60.3 0.2 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Phage_lysozyme PF00959.19 ACL95720.1 - 1.6e-11 44.6 0.0 2.3e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Phage lysozyme MgtE PF01769.16 ACL95721.3 - 5.5e-25 88.1 5.0 1.1e-24 87.1 5.0 1.5 1 0 0 1 1 1 1 Divalent cation transporter MgtE_N PF03448.17 ACL95721.3 - 1.3e-22 80.3 6.7 1.3e-22 80.3 6.7 2.8 4 0 0 4 4 4 1 MgtE intracellular N domain CBS PF00571.28 ACL95721.3 - 6.1e-07 29.8 2.3 0.0057 17.1 0.3 3.7 3 0 0 3 3 3 2 CBS domain FliG_M PF14841.6 ACL95721.3 - 0.00022 21.4 0.2 0.33 11.2 0.0 3.3 1 1 2 3 3 3 2 FliG middle domain FliMN_C PF01052.20 ACL95722.1 - 2.1e-20 72.5 0.1 2.4e-20 72.3 0.1 1.1 1 0 0 1 1 1 1 Type III flagellar switch regulator (C-ring) FliN C-term BPL_LplA_LipB PF03099.19 ACL95723.3 - 1e-06 28.7 0.0 1.5e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF805 PF05656.14 ACL95725.1 - 2.7e-16 59.8 1.6 3.2e-16 59.6 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF805) DUF3792 PF12670.7 ACL95725.1 - 0.0092 16.1 0.6 0.011 15.8 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3792) Phage_holin_3_7 PF05449.11 ACL95725.1 - 0.034 14.2 2.9 0.057 13.4 2.9 1.3 1 0 0 1 1 1 0 Putative 3TM holin, Phage_holin_3 CPSase_L_D2 PF02786.17 ACL95726.1 - 1.5e-76 256.6 0.2 2.4e-76 256.0 0.2 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ACL95726.1 - 3.3e-44 149.9 0.1 7.6e-44 148.8 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ACL95726.1 - 2.6e-32 111.1 0.0 1e-31 109.2 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain PCC_BT PF18140.1 ACL95726.1 - 1e-21 77.6 0.0 2.4e-21 76.4 0.0 1.7 1 0 0 1 1 1 1 Propionyl-coenzyme A carboxylase BT domain Biotin_lipoyl PF00364.22 ACL95726.1 - 2.4e-16 59.3 2.0 7.1e-16 57.8 2.0 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 ACL95726.1 - 5.7e-09 35.8 0.0 1.2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 ACL95726.1 - 1.1e-06 28.4 0.1 2.3e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 ACL95726.1 - 5.2e-06 26.2 0.9 0.041 13.7 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 ACL95726.1 - 3.3e-05 24.6 0.5 0.1 13.3 0.1 2.8 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.14 ACL95726.1 - 0.00012 22.2 0.2 0.00024 21.2 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain HlyD_D23 PF16576.5 ACL95726.1 - 0.0012 18.1 0.2 0.084 12.1 0.0 2.2 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_5 PF13549.6 ACL95726.1 - 0.0026 17.2 0.0 0.005 16.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 ACL95726.1 - 0.0031 17.2 0.0 0.0068 16.0 0.0 1.6 1 1 0 1 1 1 1 RimK-like ATP-grasp domain GARS_A PF01071.19 ACL95726.1 - 0.013 15.3 0.1 0.027 14.2 0.1 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 ACL95726.1 - 0.022 14.0 0.0 0.046 13.0 0.0 1.5 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp Laminin_G_3 PF13385.6 ACL95727.1 - 7.2e-13 49.0 0.8 7.2e-13 49.0 0.8 2.1 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Pentaxin PF00354.17 ACL95727.1 - 0.00074 19.3 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Pentaxin family Haem_degrading PF03928.14 ACL95728.1 - 3.5e-27 94.8 4.1 4.7e-27 94.4 4.1 1.2 1 0 0 1 1 1 1 Haem-degrading DUF5127 PF17168.4 ACL95728.1 - 0.098 12.4 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5127) DJ-1_PfpI PF01965.24 ACL95729.1 - 5.8e-20 71.7 0.0 6.6e-20 71.6 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_C26 PF07722.13 ACL95729.1 - 0.016 14.9 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase C26 GATase_3 PF07685.14 ACL95729.1 - 0.17 11.4 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain SelR PF01641.18 ACL95730.1 - 1.4e-45 154.3 0.0 1.6e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 SelR domain GST_N_3 PF13417.6 ACL95731.1 - 3.2e-09 37.1 0.0 1.4e-08 35.0 0.0 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ACL95731.1 - 3.6e-07 30.1 0.3 3.2e-06 27.1 0.1 2.6 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ACL95731.1 - 0.0004 20.6 0.3 0.0014 18.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 ACL95731.1 - 0.00081 20.1 0.1 0.016 15.9 0.0 2.7 2 1 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_3 PF14497.6 ACL95731.1 - 0.0082 16.3 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ACL95731.1 - 0.011 15.9 0.0 0.037 14.3 0.0 1.8 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain Ser_hydrolase PF06821.13 ACL95732.1 - 1.8e-69 233.0 0.0 2.1e-69 232.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase Hydrolase_4 PF12146.8 ACL95732.1 - 5.4e-05 22.6 0.1 0.0068 15.7 0.2 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ACL95732.1 - 8.2e-05 23.3 9.8 0.00015 22.4 9.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ACL95732.1 - 0.00023 20.9 0.2 1.5 8.4 0.3 2.9 2 1 1 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 ACL95732.1 - 0.0042 17.2 0.0 0.57 10.3 0.0 2.2 2 0 0 2 2 2 2 TAP-like protein Laminin_G_3 PF13385.6 ACL95733.1 - 8.7e-16 58.4 0.0 1.2e-15 58.0 0.0 1.1 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Peptidase_S58 PF03576.14 ACL95734.1 - 7.4e-59 199.7 1.6 9.2e-59 199.4 1.6 1.0 1 0 0 1 1 1 1 Peptidase family S58 GspH PF12019.8 ACL95734.1 - 0.018 15.4 0.0 0.038 14.4 0.0 1.6 1 0 0 1 1 1 0 Type II transport protein GspH MarR_2 PF12802.7 ACL95735.1 - 2.1e-08 33.9 5.2 4.2e-08 33.0 1.6 2.4 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 ACL95735.1 - 0.0053 17.2 1.0 0.017 15.6 0.5 1.9 2 0 0 2 2 2 1 Winged helix DNA-binding domain MarR PF01047.22 ACL95735.1 - 0.096 12.6 0.4 0.096 12.6 0.4 2.3 3 0 0 3 3 3 0 MarR family GP67 PF17634.2 ACL95736.2 - 0.45 11.0 3.9 23 5.5 2.4 2.6 3 0 0 3 3 3 0 Gene product 67 DUF3297 PF11730.8 ACL95738.1 - 1.1e-40 137.4 0.0 1.2e-40 137.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3297) EF-hand_1 PF00036.32 ACL95739.1 - 4e-12 44.7 2.5 0.015 14.8 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 ACL95739.1 - 6.6e-11 42.5 0.8 0.00027 21.3 0.1 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 ACL95739.1 - 4.9e-10 38.4 2.1 0.06 12.9 0.1 4.2 3 1 1 4 4 4 3 EF hand EF-hand_8 PF13833.6 ACL95739.1 - 1.1e-08 34.8 0.1 0.33 10.8 0.0 4.3 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 ACL95739.1 - 2.1e-08 33.4 3.1 0.27 11.3 0.2 4.2 4 0 0 4 4 4 3 EF-hand domain SHOCT PF09851.9 ACL95739.1 - 0.032 14.0 0.2 21 5.0 0.0 3.6 3 1 0 3 3 3 0 Short C-terminal domain Dockerin_1 PF00404.18 ACL95739.1 - 0.088 13.0 1.5 6.1 7.1 0.1 2.7 2 1 0 2 2 2 0 Dockerin type I domain DUF4198 PF10670.9 ACL95740.1 - 2.8e-41 142.2 0.5 3.3e-41 142.0 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4198) CarboxypepD_reg PF13620.6 ACL95740.1 - 0.0004 20.6 0.9 0.017 15.4 0.1 2.9 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 ACL95740.1 - 0.15 12.3 0.0 11 6.2 0.0 2.2 2 0 0 2 2 2 0 SdrD B-like domain TonB_dep_Rec PF00593.24 ACL95742.1 - 2.2e-56 192.7 23.7 6.3e-56 191.2 23.1 1.8 1 1 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 ACL95742.1 - 1.1e-25 90.2 1.2 3.5e-25 88.6 1.2 1.9 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 ACL95742.1 - 0.0018 17.3 0.1 0.004 16.2 0.0 1.5 2 0 0 2 2 2 1 Outer membrane protein beta-barrel family SNARE_assoc PF09335.11 ACL95743.1 - 3.1e-09 37.3 5.2 3.1e-09 37.3 5.2 1.8 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF3169 PF11368.8 ACL95743.1 - 0.093 12.2 0.3 0.093 12.2 0.3 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3169) DsbB PF02600.16 ACL95744.1 - 1.7e-33 116.1 8.3 2e-33 115.9 8.3 1.0 1 0 0 1 1 1 1 Disulfide bond formation protein DsbB COQ7 PF03232.13 ACL95745.1 - 4.3e-65 218.7 3.6 4.8e-65 218.5 3.6 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Ferritin PF00210.24 ACL95745.1 - 7.4e-05 22.7 0.4 0.00011 22.2 0.4 1.3 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 ACL95745.1 - 0.00066 20.1 0.4 0.0017 18.8 0.4 1.7 1 1 0 1 1 1 1 Rubrerythrin Peptidase_M1 PF01433.20 ACL95746.1 - 2.9e-15 56.4 0.0 4.7e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 ACL95746.1 - 5.3e-09 36.5 0.0 8.5e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 ACL95746.1 - 0.69 10.3 3.4 12 6.4 3.4 2.3 1 1 0 1 1 1 0 M61 glycyl aminopeptidase VanZ PF04892.12 ACL95747.1 - 1.2e-06 29.2 0.7 1.6e-06 28.7 0.7 1.2 1 0 0 1 1 1 1 VanZ like family DUF2809 PF10990.8 ACL95747.1 - 0.023 15.4 0.0 0.18 12.5 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2809) HNH_5 PF14279.6 ACL95748.1 - 2.5e-16 59.3 0.0 3.8e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 HNH endonuclease HNH PF01844.23 ACL95748.1 - 1.9e-14 53.5 0.0 2.7e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 HNH endonuclease HNH_4 PF13395.6 ACL95748.1 - 1.6e-05 24.7 0.0 2.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease HhH-GPD PF00730.25 ACL95749.1 - 1.1e-16 61.2 0.0 1.6e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH_5 PF14520.6 ACL95749.1 - 0.022 15.4 0.0 0.06 14.0 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain GreA_GreB PF01272.19 ACL95750.1 - 7e-18 64.3 0.0 1e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term TetR_N PF00440.23 ACL95752.2 - 3.3e-15 55.6 0.2 6.8e-15 54.6 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_33 PF13305.6 ACL95752.2 - 3.4e-09 37.4 1.5 6.5e-09 36.5 0.1 2.1 2 1 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain tRNA-synt_1c PF00749.21 ACL95753.1 - 9.4e-47 159.4 0.0 6.3e-46 156.7 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain DUF2724 PF10893.8 ACL95753.1 - 0.035 14.0 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2724) HTH_34 PF13601.6 ACL95754.1 - 2.4e-31 107.7 0.0 2.8e-31 107.5 0.0 1.0 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_20 PF12840.7 ACL95754.1 - 4.4e-11 42.7 0.1 1.5e-10 41.0 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_5 PF01022.20 ACL95754.1 - 3.2e-10 39.7 0.0 6.7e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_27 PF13463.6 ACL95754.1 - 0.00019 21.9 0.0 0.00028 21.3 0.0 1.3 1 0 0 1 1 1 1 Winged helix DNA-binding domain HxlR PF01638.17 ACL95754.1 - 0.00066 19.5 0.0 0.00075 19.3 0.0 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix PadR PF03551.14 ACL95754.1 - 0.00083 19.3 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family MarR PF01047.22 ACL95754.1 - 0.0011 18.9 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 ACL95754.1 - 0.0019 18.0 0.1 0.0027 17.5 0.1 1.4 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 ACL95754.1 - 0.028 14.0 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding SgrR_N PF12793.7 ACL95754.1 - 0.14 12.4 0.0 0.17 12.1 0.0 1.1 1 0 0 1 1 1 0 Sugar transport-related sRNA regulator N-term TrmB PF01978.19 ACL95754.1 - 0.14 12.0 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF2513 PF10711.9 ACL95754.1 - 0.19 12.0 0.0 0.22 11.8 0.0 1.1 1 0 0 1 1 1 0 Hypothetical protein (DUF2513) CPP1-like PF11833.8 ACL95755.2 - 0.83 9.3 4.3 1 9.0 1.7 2.0 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Acyl_transf_3 PF01757.22 ACL95756.1 - 2.8e-23 82.5 35.0 3.4e-23 82.3 35.0 1.1 1 0 0 1 1 1 1 Acyltransferase family Acetyltransf_1 PF00583.25 ACL95757.1 - 2.8e-11 43.7 0.0 4.6e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 ACL95757.1 - 8e-08 32.1 0.0 1.4e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 ACL95757.1 - 1e-05 25.9 0.0 1.5e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ACL95757.1 - 0.00034 20.5 0.0 0.00048 20.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ACL95757.1 - 0.00046 20.9 0.0 0.00084 20.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 ACL95757.1 - 0.0034 17.0 0.0 0.0047 16.5 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_6 PF13480.7 ACL95757.1 - 0.021 15.0 2.4 0.067 13.3 0.7 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 ACL95757.1 - 0.075 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ACL95757.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Redoxin PF08534.10 ACL95758.1 - 3.2e-17 62.6 0.0 4.3e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 ACL95758.1 - 1.3e-14 54.2 0.0 2.1e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 ACL95758.1 - 1.4e-10 41.3 0.0 2.4e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 ACL95758.1 - 1.2e-07 31.6 0.1 3.3e-07 30.2 0.1 1.7 1 1 1 2 2 2 1 Thioredoxin SCO1-SenC PF02630.14 ACL95758.1 - 0.00014 21.8 0.1 0.00021 21.2 0.1 1.2 1 0 0 1 1 1 1 SCO1/SenC GSHPx PF00255.19 ACL95758.1 - 0.00098 18.7 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione peroxidase Thioredoxin_2 PF13098.6 ACL95758.1 - 0.035 14.6 0.0 0.084 13.3 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain TetR_C_16 PF17920.1 ACL95758.1 - 0.082 13.2 0.4 0.26 11.5 0.2 1.9 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF2568 PF10823.8 ACL95758.1 - 0.13 12.5 2.1 2.3 8.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2568) Lyase_1 PF00206.20 ACL95759.1 - 1.3e-72 244.9 0.0 1.7e-72 244.5 0.0 1.1 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 ACL95759.1 - 6.6e-24 84.4 0.3 2.2e-23 82.8 0.3 2.0 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal PLAC9 PF15205.6 ACL95759.1 - 0.011 16.1 0.0 0.039 14.3 0.0 1.9 2 0 0 2 2 2 0 Placenta-specific protein 9 Orn_Arg_deC_N PF02784.16 ACL95761.1 - 1.6e-57 194.7 0.0 2e-57 194.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 ACL95761.1 - 2.6e-28 98.1 0.0 3.7e-28 97.6 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.20 ACL95761.1 - 4.7e-07 29.7 1.3 9.5e-07 28.7 1.3 1.5 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain Pribosyltran PF00156.27 ACL95762.3 - 1.4e-16 60.5 0.0 1.8e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.6 ACL95762.3 - 0.012 15.7 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain UPRTase PF14681.6 ACL95762.3 - 0.018 14.5 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase zinc_ribbon_4 PF13717.6 ACL95763.2 - 4e-13 49.0 0.8 6.4e-13 48.4 0.2 1.7 2 0 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_5 PF13719.6 ACL95763.2 - 4.9e-07 29.4 0.2 7.4e-07 28.8 0.2 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DUF3426 PF11906.8 ACL95763.2 - 4.9e-05 23.5 0.1 8.8e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3426) TF_Zn_Ribbon PF08271.12 ACL95763.2 - 0.0095 15.4 0.9 0.032 13.8 1.0 1.8 2 0 0 2 2 2 1 TFIIB zinc-binding TFIIS_C PF01096.18 ACL95763.2 - 0.029 14.2 0.5 0.67 9.9 0.1 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Lar_restr_allev PF14354.6 ACL95763.2 - 0.19 12.1 2.5 0.55 10.7 2.5 1.8 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-NADH-PPase PF09297.11 ACL95763.2 - 0.27 10.9 2.0 2.1 8.1 0.3 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain MSA-2c PF12238.8 ACL95763.2 - 0.31 11.0 3.4 0.59 10.1 3.4 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c DNA_RNApol_7kD PF03604.13 ACL95763.2 - 3 7.6 3.9 28 4.5 4.1 2.2 1 1 1 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit ABC_tran PF00005.27 ACL95764.3 - 7.7e-32 110.7 0.0 9.7e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ACL95764.3 - 1.6e-10 41.3 0.0 0.00029 20.7 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ACL95764.3 - 0.0002 21.8 0.1 0.00029 21.3 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 ACL95764.3 - 0.00026 20.6 0.0 0.00052 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ACL95764.3 - 0.0023 17.7 0.0 0.0039 16.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ACL95764.3 - 0.0025 17.8 0.0 0.0063 16.4 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 ACL95764.3 - 0.013 15.3 0.0 0.03 14.0 0.0 1.5 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 ACL95764.3 - 0.017 14.5 0.0 1.9 7.8 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_27 PF13514.6 ACL95764.3 - 0.071 12.7 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 ACL95764.3 - 0.092 13.0 0.1 0.21 11.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ACL95764.3 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin DUF815 PF05673.13 ACL95764.3 - 0.2 10.8 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) cobW PF02492.19 ACL95764.3 - 0.22 11.1 0.1 4.2 6.9 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 ACL95764.3 - 0.26 11.8 0.0 0.38 11.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF218 PF02698.17 ACL95766.1 - 1.5e-13 50.9 0.1 2.5e-13 50.2 0.1 1.3 1 0 0 1 1 1 1 DUF218 domain Acyltransferase PF01553.21 ACL95767.1 - 6.6e-18 64.6 0.0 9.4e-18 64.1 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Bap31 PF05529.12 ACL95767.1 - 0.16 11.8 0.8 0.27 11.1 0.8 1.4 1 0 0 1 1 1 0 Bap31/Bap29 transmembrane region ChaC PF04752.12 ACL95768.1 - 6.4e-57 192.5 0.1 7.3e-57 192.3 0.1 1.0 1 0 0 1 1 1 1 ChaC-like protein GGACT PF06094.12 ACL95768.1 - 3.5e-06 27.6 0.1 4.6e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like DUF2931 PF11153.8 ACL95768.1 - 0.23 11.1 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2931) DUF2125 PF09898.9 ACL95769.1 - 4.8e-68 230.2 12.8 5.5e-68 230.0 12.8 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2125) CM_2 PF01817.21 ACL95770.2 - 3.9e-14 52.7 0.0 5.9e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Chorismate mutase type II Aminotran_1_2 PF00155.21 ACL95771.1 - 4.4e-46 157.7 0.0 5e-46 157.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 ACL95771.1 - 2.5e-05 23.4 0.0 3.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 ACL95771.1 - 0.043 12.3 0.0 0.073 11.6 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme PDH PF02153.17 ACL95772.1 - 1.5e-71 240.5 0.1 1.7e-71 240.3 0.1 1.0 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 ACL95772.1 - 1.7e-07 31.7 0.8 3.9e-07 30.6 0.8 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 ACL95772.1 - 1.5e-06 27.7 2.4 2.8e-06 26.8 2.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 ACL95772.1 - 4.3e-06 27.0 0.7 8e-06 26.1 0.4 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 ACL95772.1 - 3.1e-05 24.2 1.2 0.00017 21.8 1.5 2.0 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 ACL95772.1 - 0.00037 19.9 0.1 0.00083 18.8 0.1 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 ACL95772.1 - 0.00051 20.0 1.9 0.00093 19.2 1.4 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase OCD_Mu_crystall PF02423.15 ACL95772.1 - 0.00076 18.5 1.4 0.0011 18.0 1.4 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family IlvN PF07991.12 ACL95772.1 - 0.0045 16.6 0.1 0.008 15.8 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain GFO_IDH_MocA PF01408.22 ACL95772.1 - 0.021 15.7 0.6 0.078 13.8 0.2 2.1 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.18 ACL95772.1 - 0.028 14.7 4.6 0.077 13.3 2.6 2.4 2 1 0 2 2 2 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.23 ACL95772.1 - 0.034 14.1 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus THF_DHG_CYH_C PF02882.19 ACL95772.1 - 0.036 13.4 0.7 0.09 12.1 0.5 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_3 PF03447.16 ACL95772.1 - 0.13 12.9 0.6 0.3 11.8 0.6 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 ACL95772.1 - 0.22 11.6 2.9 0.34 11.0 1.5 2.0 2 1 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain EF-hand_5 PF13202.6 ACL95774.1 - 4.5e-11 41.7 2.3 4.4e-06 25.9 0.5 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 ACL95774.1 - 3.2e-10 39.1 0.3 2.7e-05 23.8 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 ACL95774.1 - 4e-10 38.5 1.2 8.4e-06 25.0 0.5 2.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 ACL95774.1 - 3.5e-06 27.4 0.0 0.0017 18.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 ACL95774.1 - 0.013 15.3 0.5 1.1 9.1 0.1 2.2 2 0 0 2 2 2 0 EF-hand domain pair PepSY_2 PF13670.6 ACL95774.1 - 0.07 13.1 0.2 0.099 12.7 0.2 1.3 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Glyco_hydro_9 PF00759.19 ACL95775.1 - 4.5e-99 332.7 4.3 5.5e-99 332.4 4.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 CelD_N PF02927.14 ACL95775.1 - 4.2e-20 72.4 0.0 7.8e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Cellulase N-terminal ig-like domain YCII PF03795.14 ACL95776.2 - 0.0046 17.3 0.3 0.0071 16.7 0.3 1.4 1 1 0 1 1 1 1 YCII-related domain TraB PF01963.17 ACL95777.1 - 2.2e-67 227.7 0.2 2.5e-67 227.6 0.2 1.0 1 0 0 1 1 1 1 TraB family Abhydrolase_6 PF12697.7 ACL95778.1 - 6.2e-13 49.9 7.4 6.2e-13 49.9 7.4 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ACL95778.1 - 7e-13 48.8 0.2 2.6e-12 46.9 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ACL95778.1 - 0.00035 19.9 0.5 0.00088 18.6 0.5 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 ACL95778.1 - 0.0038 16.9 0.1 0.008 15.8 0.1 1.5 1 0 0 1 1 1 1 Putative esterase UPF0227 PF05728.12 ACL95778.1 - 0.05 13.5 0.0 0.09 12.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) TatC PF00902.18 ACL95779.1 - 0.23 11.2 12.3 0.86 9.4 12.3 1.7 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) DUF697 PF05128.12 ACL95779.1 - 1.5 8.5 8.5 2.9 7.6 0.2 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF697) HTH_3 PF01381.22 ACL95780.1 - 4.2e-15 55.5 0.0 4.6e-15 55.4 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 ACL95780.1 - 2.7e-13 49.7 0.0 3e-13 49.6 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 ACL95780.1 - 9.8e-12 45.1 0.0 1.1e-11 44.9 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 ACL95780.1 - 4.1e-06 27.1 0.0 4.3e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 ACL95780.1 - 9.3e-06 25.4 0.1 1e-05 25.3 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_11 PF08279.12 ACL95780.1 - 2e-05 24.4 0.1 3.1e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 HTH domain HTH_23 PF13384.6 ACL95780.1 - 0.00019 21.1 0.1 0.00031 20.4 0.1 1.3 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4 PF04545.16 ACL95780.1 - 0.00049 19.6 0.0 0.00097 18.6 0.0 1.4 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_38 PF13936.6 ACL95780.1 - 0.0011 18.6 0.0 0.0045 16.7 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.6 ACL95780.1 - 0.0029 17.1 0.0 0.004 16.7 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_37 PF13744.6 ACL95780.1 - 0.005 16.8 0.0 0.0054 16.7 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 ACL95780.1 - 0.019 14.9 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_Crp_2 PF13545.6 ACL95780.1 - 0.022 14.7 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain YdaS_antitoxin PF15943.5 ACL95780.1 - 0.023 14.6 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Sigma70_r4_2 PF08281.12 ACL95780.1 - 0.027 14.1 0.0 0.061 13.0 0.0 1.6 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_29 PF13551.6 ACL95780.1 - 0.083 12.9 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 Winged helix-turn helix Phage_CI_repr PF07022.13 ACL95780.1 - 0.14 12.3 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain DUF5360 PF17314.2 ACL95781.3 - 0.00094 19.3 0.2 0.0013 18.8 0.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5360) DUF1427 PF07235.11 ACL95781.3 - 0.097 12.6 0.9 1.5 8.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1427) DUF3099 PF11298.8 ACL95781.3 - 1.4 9.1 7.3 1.1 9.5 5.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) SLATT_2 PF18183.1 ACL95782.1 - 0.015 15.1 0.5 0.023 14.5 0.5 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 2 UPF0542 PF15086.6 ACL95782.1 - 0.032 14.2 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 G6B PF15096.6 ACL95783.2 - 0.0089 15.8 0.1 0.0091 15.8 0.1 1.1 1 0 0 1 1 1 1 G6B family DUF726 PF05277.12 ACL95783.2 - 1.4 7.8 6.1 1.7 7.5 6.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF726) DCD PF06559.11 ACL95785.3 - 3.7e-150 499.7 0.0 3e-75 253.3 0.0 2.0 1 1 1 2 2 2 2 2'-deoxycytidine 5'-triphosphate deaminase (DCD) Cys_Met_Meta_PP PF01053.20 ACL95786.1 - 8.7e-124 412.9 0.0 9.9e-124 412.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 ACL95786.1 - 1.9e-07 30.7 0.4 4.8e-07 29.4 0.4 1.7 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 ACL95786.1 - 4.5e-06 25.9 0.0 8.3e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V GDC-P PF02347.16 ACL95786.1 - 0.00037 19.4 0.0 0.00052 19.0 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Aminotran_1_2 PF00155.21 ACL95786.1 - 0.0048 16.1 0.0 0.0059 15.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 ACL95786.1 - 0.018 13.6 0.0 0.067 11.7 0.1 1.8 1 1 0 1 1 1 0 Methionine gamma-lyase DUF525 PF04379.14 ACL95787.1 - 1.8e-32 111.4 0.0 2.3e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 ApaG domain HSP33 PF01430.19 ACL95789.1 - 5.7e-79 265.3 0.0 6.6e-79 265.1 0.0 1.0 1 0 0 1 1 1 1 Hsp33 protein OTCace PF00185.24 ACL95790.1 - 1.2e-48 165.1 0.0 1.9e-48 164.5 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 ACL95790.1 - 1e-46 158.6 0.1 1.5e-46 158.1 0.1 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain NAD_binding_10 PF13460.6 ACL95790.1 - 0.078 12.9 1.5 3.1 7.7 0.2 2.2 2 0 0 2 2 2 0 NAD(P)H-binding TOC159_MAD PF11886.8 ACL95790.1 - 0.087 11.7 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Translocase of chloroplast 159/132, membrane anchor domain TAFA PF12020.8 ACL95790.1 - 0.095 13.2 0.0 0.29 11.6 0.0 1.8 1 0 0 1 1 1 0 TAFA family Aminotran_3 PF00202.21 ACL95791.1 - 9.7e-107 357.1 0.0 1.3e-106 356.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III ABC2_membrane PF01061.24 ACL95792.1 - 7.8e-31 107.1 15.8 7.8e-31 107.1 15.8 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 ACL95792.1 - 5.8e-05 22.4 16.0 5.8e-05 22.4 16.0 1.6 1 1 0 1 1 1 1 ABC-2 family transporter protein GcrA PF07750.11 ACL95793.2 - 7.4e-65 218.3 0.1 8.3e-65 218.1 0.1 1.0 1 0 0 1 1 1 1 GcrA cell cycle regulator HTH_23 PF13384.6 ACL95793.2 - 0.073 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Rib_recp_KP_reg PF05104.12 ACL95793.2 - 8.1 7.5 12.3 0.9 10.6 8.2 1.4 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region Exonuc_VII_L PF02601.15 ACL95794.1 - 2.1e-92 309.9 0.0 2.7e-92 309.6 0.0 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit tRNA_anti_2 PF13742.6 ACL95794.1 - 3.7e-23 81.5 0.0 6.2e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti-codon PF01336.25 ACL95794.1 - 1.3e-05 25.1 0.1 2.7e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain UPF0126 PF03458.13 ACL95794.1 - 0.085 12.8 0.1 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 UPF0126 domain Pox_A_type_inc PF04508.12 ACL95794.1 - 4.7 7.2 6.7 0.3 11.0 0.8 2.2 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF2093 PF09866.9 ACL95795.1 - 7.3e-23 79.7 0.0 9.7e-23 79.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2093) Peptidase_M23 PF01551.22 ACL95796.3 - 2.7e-24 85.2 0.0 4.6e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M23 Response_reg PF00072.24 ACL95797.1 - 3.6e-21 75.4 0.1 4.3e-21 75.2 0.1 1.1 1 0 0 1 1 1 1 Response regulator receiver domain RICTOR_N PF14664.6 ACL95797.1 - 0.073 12.0 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term Lip_A_acyltrans PF03279.13 ACL95798.1 - 6e-46 156.9 0.0 7.4e-46 156.7 0.0 1.0 1 0 0 1 1 1 1 Bacterial lipid A biosynthesis acyltransferase HTH_3 PF01381.22 ACL95799.1 - 4.3e-11 42.7 0.1 7.8e-11 41.9 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 ACL95799.1 - 7.1e-11 42.0 0.1 1.7e-10 40.8 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_31 PF13560.6 ACL95799.1 - 3.9e-09 36.7 3.0 3.9e-09 36.7 3.0 1.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_25 PF13413.6 ACL95799.1 - 0.055 13.3 0.3 0.1 12.4 0.3 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain MqsA_antitoxin PF15731.5 ACL95799.1 - 0.056 13.5 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA Pou PF00157.17 ACL95799.1 - 0.13 12.2 0.3 0.25 11.3 0.3 1.4 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain Inositol_P PF00459.25 ACL95800.1 - 1e-49 169.5 0.0 1.2e-49 169.3 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Hydrolase_4 PF12146.8 ACL95801.1 - 6.6e-40 136.9 0.0 7.7e-40 136.6 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ACL95801.1 - 7e-15 55.4 0.0 1.7e-14 54.1 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ACL95801.1 - 8.6e-13 49.4 8.1 1.1e-12 49.0 8.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ACL95801.1 - 6e-05 22.6 0.0 0.00023 20.7 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Ser_hydrolase PF06821.13 ACL95801.1 - 0.091 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase SCP2 PF02036.17 ACL95802.1 - 4.4e-13 49.6 0.5 5.3e-13 49.3 0.5 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family HU-CCDC81_euk_2 PF18289.1 ACL95802.1 - 0.082 13.1 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 DUF2987 PF11205.8 ACL95803.1 - 0.0034 17.3 0.0 0.0047 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2987) CarboxypepD_reg PF13620.6 ACL95803.1 - 0.049 13.9 0.0 0.081 13.2 0.0 1.4 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Methyltransf_25 PF13649.6 ACL95804.1 - 0.11 13.2 0.0 0.2 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 ACL95805.1 - 6.7e-05 22.8 0.0 0.00015 21.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ACL95805.1 - 0.012 16.2 0.1 0.067 13.8 0.1 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 ACL95805.1 - 0.03 15.0 0.0 0.12 13.1 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 ACL95805.1 - 0.047 14.4 0.0 0.09 13.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 ACL95805.1 - 0.072 12.4 0.0 0.38 10.0 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 ACL95805.1 - 0.095 12.4 0.0 0.19 11.4 0.0 1.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 ACL95805.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase HSP20 PF00011.21 ACL95806.1 - 1.6e-18 66.8 0.0 2.1e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ACL95806.1 - 0.0011 18.5 0.2 0.0026 17.3 0.0 1.8 2 1 0 2 2 2 1 HSP20-like domain found in ArsA baeRF_family11 PF18855.1 ACL95806.1 - 0.065 13.5 0.0 0.54 10.6 0.0 2.0 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 11 Pentapeptide PF00805.22 ACL95807.1 - 3.8e-62 205.4 37.8 4.9e-13 48.4 3.7 9.4 5 4 3 9 9 9 8 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 ACL95807.1 - 2.3e-29 101.4 0.0 5.3e-06 26.5 0.0 5.3 4 2 0 4 4 4 4 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 ACL95807.1 - 3.2e-26 91.2 0.4 1.6e-05 24.9 0.5 6.9 4 2 2 6 6 6 6 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 ACL95808.1 - 9.4e-66 216.9 50.6 2.9e-13 49.1 1.1 9.7 7 4 3 11 11 11 8 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 ACL95808.1 - 7.3e-33 112.6 0.0 4.3e-08 33.2 0.0 5.0 4 1 1 5 5 5 5 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 ACL95808.1 - 1.8e-31 108.0 0.1 1e-05 25.5 0.1 7.4 5 3 2 7 7 7 6 Pentapeptide repeats (9 copies) His_Phos_1 PF00300.22 ACL95809.1 - 4e-34 118.0 0.5 1.4e-31 109.7 0.5 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SIS PF01380.22 ACL95811.1 - 3.8e-25 88.2 0.1 5.6e-25 87.7 0.1 1.2 1 0 0 1 1 1 1 SIS domain CBS PF00571.28 ACL95811.1 - 3.3e-17 62.7 1.3 2.8e-09 37.3 0.1 3.0 3 0 0 3 3 3 2 CBS domain SIS_2 PF13580.6 ACL95811.1 - 0.0021 18.0 1.0 0.72 9.9 0.0 2.5 1 1 1 2 2 2 2 SIS domain PGM_PMM_I PF02878.16 ACL95812.1 - 7e-27 93.8 0.0 1.7e-26 92.5 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 ACL95812.1 - 1.4e-25 89.9 0.6 4e-25 88.4 0.6 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 ACL95812.1 - 1.4e-15 57.5 0.0 2.5e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 ACL95812.1 - 1.5e-08 34.6 0.3 4.5e-08 33.1 0.3 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Acetyltransf_10 PF13673.7 ACL95813.1 - 1e-13 51.3 0.0 1.1e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ACL95813.1 - 1e-10 41.9 0.0 1.3e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ACL95813.1 - 9.9e-09 35.5 0.0 1.6e-08 34.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 ACL95813.1 - 0.0094 15.9 0.0 0.079 12.9 0.0 2.0 1 1 0 1 1 1 1 FR47-like protein PNP_UDP_1 PF01048.20 ACL95814.1 - 6.2e-52 176.2 2.7 7.3e-52 175.9 2.7 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily NUP PF06516.11 ACL95814.1 - 4.8e-05 22.7 0.2 0.0001 21.7 0.0 1.6 2 0 0 2 2 2 1 Purine nucleoside permease (NUP) DUF5353 PF17304.2 ACL95814.1 - 0.0039 16.9 1.2 0.0091 15.7 0.2 2.0 2 0 0 2 2 2 1 Family of unknown function (DUF5353) DUF498 PF04430.14 ACL95814.1 - 0.025 14.7 0.0 0.46 10.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF498/DUF598) Dabb PF07876.12 ACL95815.1 - 5.4e-21 75.0 0.2 6.3e-21 74.8 0.2 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain UPRTase PF14681.6 ACL95816.1 - 4.9e-71 238.5 0.0 5.7e-71 238.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 ACL95816.1 - 5.5e-10 39.0 0.0 9.6e-10 38.2 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain DUF4153 PF13687.6 ACL95816.1 - 0.15 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4153) Ald_Xan_dh_C2 PF02738.18 ACL95817.1 - 6.9e-72 242.7 4.0 7.8e-39 133.5 0.0 3.0 2 1 1 3 3 3 3 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 ACL95817.1 - 0.0005 20.4 0.0 0.019 15.3 0.0 2.5 2 0 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 ACL95818.1 - 2.8e-24 84.9 1.0 2.8e-24 84.9 1.0 1.7 2 0 0 2 2 2 1 [2Fe-2S] binding domain Fer2 PF00111.27 ACL95818.1 - 8.7e-09 35.2 0.3 8.7e-09 35.2 0.3 2.0 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 ACL95818.1 - 5.1e-06 26.5 1.3 5.9e-06 26.3 0.5 1.5 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 ACL95818.1 - 0.038 14.1 0.5 0.11 12.5 0.5 1.8 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain NUDIX PF00293.28 ACL95819.2 - 1.3e-08 34.9 0.6 1.6e-08 34.6 0.6 1.1 1 0 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.25 ACL95820.1 - 6.9e-09 36.1 0.0 1e-08 35.6 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 ACL95820.1 - 0.00036 20.3 0.0 0.00089 19.0 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 ACL95820.1 - 0.0016 19.0 0.0 1.5 9.5 0.0 2.5 1 1 1 2 2 2 2 Helix-hairpin-helix domain EndIII_4Fe-2S PF10576.9 ACL95820.1 - 0.068 13.5 2.3 0.068 13.5 2.3 2.4 3 0 0 3 3 3 0 Iron-sulfur binding domain of endonuclease III HHH_2 PF12826.7 ACL95820.1 - 0.075 13.1 0.0 2.2 8.5 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif Herpes_UL69 PF05459.12 ACL95820.1 - 0.11 11.8 0.3 0.17 11.2 0.3 1.2 1 0 0 1 1 1 0 Herpesvirus transcriptional regulator family Peptidase_M15 PF01427.17 ACL95821.1 - 1.1e-36 126.5 0.1 2.3e-36 125.4 0.1 1.5 1 1 0 1 1 1 1 D-ala-D-ala dipeptidase VanY PF02557.17 ACL95821.1 - 1.2e-05 25.1 0.1 2.3e-05 24.2 0.1 1.5 1 1 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Peptidase_M15_4 PF13539.6 ACL95821.1 - 0.0057 17.1 0.0 0.014 15.9 0.0 1.6 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Aldedh PF00171.22 ACL95822.1 - 1.6e-135 452.2 0.3 1.8e-135 452.0 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 ACL95822.1 - 0.0014 17.7 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) EP400_N PF15790.5 ACL95822.1 - 0.026 13.4 0.0 0.038 12.8 0.0 1.1 1 0 0 1 1 1 0 E1A-binding protein p400, N-terminal Flavin_Reduct PF01613.18 ACL95823.1 - 2.1e-42 144.8 0.0 2.6e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 Flavin reductase like domain FANCAA PF15146.6 ACL95823.1 - 0.096 11.8 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Fanconi anemia-associated Glycos_transf_2 PF00535.26 ACL95825.1 - 5.2e-21 75.2 0.0 7.2e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ACL95825.1 - 2.1e-09 37.6 0.0 2.8e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 ACL95825.1 - 0.052 13.0 0.0 0.072 12.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Acetyltransf_6 PF13480.7 ACL95826.1 - 4.6e-32 111.1 4.8 9.2e-30 103.7 0.4 2.8 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain GAF_2 PF13185.6 ACL95827.1 - 7.9e-13 48.9 0.0 1.2e-12 48.4 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 ACL95827.1 - 1.1e-07 32.5 0.0 1.3e-07 32.3 0.0 1.2 1 0 0 1 1 1 1 GAF domain TruB_C PF09142.11 ACL95827.1 - 0.017 14.9 0.4 0.086 12.6 0.0 2.2 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal MCPsignal PF00015.21 ACL95829.1 - 1.3e-51 174.8 20.8 1.3e-51 174.8 20.8 3.6 4 1 0 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain dCache_1 PF02743.18 ACL95829.1 - 1.2e-19 71.1 2.6 1.4e-19 70.9 0.0 2.5 3 1 0 3 3 3 1 Cache domain HAMP PF00672.25 ACL95829.1 - 1.3e-07 31.9 9.9 3.8e-07 30.4 0.0 4.3 5 0 0 5 5 5 2 HAMP domain Tox-URI2 PF15653.6 ACL95829.1 - 0.08 13.2 0.4 2.3 8.6 0.0 2.6 3 0 0 3 3 3 0 URI fold toxin 2 zf-C4H2 PF10146.9 ACL95829.1 - 1.8 8.9 4.7 0.33 11.2 0.1 2.1 3 0 0 3 3 3 0 Zinc finger-containing protein YjcZ PF13990.6 ACL95829.1 - 3.6 6.9 13.0 2.9 7.2 2.1 3.2 3 0 0 3 3 3 0 YjcZ-like protein DASH_Duo1 PF08651.10 ACL95829.1 - 8 6.3 7.7 6.8 6.5 1.4 3.6 4 0 0 4 4 4 0 DASH complex subunit Duo1 Glyco_hydro_15 PF00723.21 ACL95830.1 - 4.6e-76 256.4 0.0 5.8e-76 256.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Glucodextran_N PF09137.11 ACL95830.1 - 4.8e-69 232.8 5.3 6.7e-69 232.4 5.3 1.2 1 0 0 1 1 1 1 Glucodextranase, domain N MFS_1 PF07690.16 ACL95831.2 - 3.9e-16 58.9 64.6 3.9e-10 39.2 32.1 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ACL95831.2 - 9.8e-09 34.3 3.8 9.8e-09 34.3 3.8 3.4 2 1 0 2 2 2 1 MFS/sugar transport protein Peripla_BP_3 PF13377.6 ACL95832.1 - 8.6e-33 114.0 0.2 1.7e-32 113.1 0.1 1.5 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 ACL95832.1 - 4.7e-20 72.2 0.0 6e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 ACL95832.1 - 4.8e-14 52.6 0.0 8.7e-14 51.7 0.0 1.4 1 1 0 1 1 1 1 Periplasmic binding protein domain LacI PF00356.21 ACL95832.1 - 1.1e-11 44.3 0.0 2.7e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family HTH_3 PF01381.22 ACL95832.1 - 0.041 14.0 0.0 0.092 12.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix HTH_Crp_2 PF13545.6 ACL95832.1 - 0.1 12.6 0.0 0.38 10.8 0.0 2.0 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Alpha-amylase PF00128.24 ACL95833.1 - 3.2e-83 280.1 0.0 2.2e-82 277.3 0.0 1.9 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF3459 PF11941.8 ACL95833.1 - 0.00034 20.9 0.0 0.00094 19.5 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) hDGE_amylase PF14701.6 ACL95833.1 - 0.19 10.8 0.0 0.27 10.3 0.0 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Alpha-amylase PF00128.24 ACL95834.2 - 7e-68 229.7 0.0 9.7e-68 229.2 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 ACL95834.2 - 1.7e-05 24.8 0.0 3.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain TonB_dep_Rec PF00593.24 ACL95835.1 - 2e-25 90.6 52.0 1.9e-24 87.4 44.1 2.9 1 1 0 2 2 2 1 TonB dependent receptor Plug PF07715.15 ACL95835.1 - 4.8e-16 59.3 2.4 2.9e-15 56.8 0.4 2.6 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain Trp_halogenase PF04820.14 ACL95836.2 - 3.1e-195 649.4 0.0 3.6e-195 649.1 0.0 1.0 1 0 0 1 1 1 1 Tryptophan halogenase DAO PF01266.24 ACL95836.2 - 7.8e-06 25.7 1.1 1.9e-05 24.5 1.3 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ACL95836.2 - 0.0072 16.3 0.5 0.72 9.8 0.3 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 ACL95836.2 - 0.024 14.9 0.7 0.072 13.3 0.7 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 ACL95836.2 - 0.053 12.9 1.0 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase rve_3 PF13683.6 ACL95838.1 - 4.2e-32 109.7 0.1 1e-31 108.5 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain rve PF00665.26 ACL95838.1 - 1.6e-23 83.2 0.0 2.8e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 ACL95838.1 - 1.6e-09 37.7 6.5 3.8e-09 36.5 6.5 1.6 1 0 0 1 1 1 1 HTH-like domain rve_2 PF13333.6 ACL95838.1 - 0.0013 18.8 0.0 0.0026 17.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain HTH_32 PF13565.6 ACL95838.1 - 4.6 7.9 15.2 2.9 8.6 2.3 3.6 2 1 1 4 4 4 0 Homeodomain-like domain HTH_Tnp_1 PF01527.20 ACL95839.1 - 6.3e-22 77.7 0.3 7.5e-22 77.4 0.3 1.1 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 ACL95839.1 - 6.7e-05 22.9 0.1 0.00016 21.7 0.1 1.8 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 ACL95839.1 - 0.00034 20.3 0.1 0.00084 19.1 0.1 1.8 1 1 0 1 1 1 1 Homeodomain-like domain HTH_11 PF08279.12 ACL95839.1 - 0.0013 18.7 0.1 0.003 17.5 0.0 1.6 2 0 0 2 2 2 1 HTH domain HTH_29 PF13551.6 ACL95839.1 - 0.0045 17.0 0.1 0.013 15.5 0.1 2.0 1 1 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_1_2 PF13022.6 ACL95839.1 - 0.0058 16.8 0.1 0.013 15.7 0.1 1.6 1 1 0 1 1 1 1 Helix-turn-helix of insertion element transposase CENP-B_N PF04218.13 ACL95839.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_AsnC-type PF13404.6 ACL95839.1 - 0.02 14.7 0.1 0.09 12.6 0.0 2.1 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_psq PF05225.16 ACL95839.1 - 0.027 14.2 0.2 2.1 8.2 0.0 2.3 1 1 1 2 2 2 0 helix-turn-helix, Psq domain Terminase_5 PF06056.12 ACL95839.1 - 0.035 14.0 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_24 PF13412.6 ACL95839.1 - 0.047 13.3 2.3 0.19 11.3 0.0 2.7 3 1 1 4 4 4 0 Winged helix-turn-helix DNA-binding MerR PF00376.23 ACL95839.1 - 0.08 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 MerR family regulatory protein YdaS_antitoxin PF15943.5 ACL95839.1 - 0.1 12.5 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT MerR_1 PF13411.6 ACL95839.1 - 0.11 12.6 0.0 0.3 11.2 0.0 1.9 2 1 0 2 2 2 0 MerR HTH family regulatory protein SIMPL PF04402.14 ACL95843.2 - 1.4e-49 169.3 6.5 1.7e-49 169.0 6.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Mcm10 PF09332.11 ACL95843.2 - 0.12 11.8 0.2 0.16 11.4 0.2 1.1 1 0 0 1 1 1 0 Mcm10 replication factor DUF732 PF05305.14 ACL95843.2 - 6 7.3 13.0 1.9 8.9 8.9 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF732) TAT_signal PF10518.9 ACL95844.1 - 7.2 6.6 7.3 0.26 11.2 1.2 1.8 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence Asp_decarbox PF02261.16 ACL95845.1 - 3.8e-50 168.6 0.1 4.2e-50 168.5 0.1 1.0 1 0 0 1 1 1 1 Aspartate decarboxylase Peptidase_M23 PF01551.22 ACL95847.1 - 1.9e-13 50.4 0.7 2.6e-13 50.0 0.7 1.2 1 0 0 1 1 1 1 Peptidase family M23 RnfC_N PF13375.6 ACL95847.1 - 0.077 13.0 0.1 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain Biotin_lipoyl_2 PF13533.6 ACL95847.1 - 0.17 11.7 0.1 0.31 10.9 0.1 1.4 1 0 0 1 1 1 0 Biotin-lipoyl like Biotin_lipoyl PF00364.22 ACL95847.1 - 0.22 11.4 0.0 0.53 10.2 0.0 1.6 1 0 0 1 1 1 0 Biotin-requiring enzyme Abhydrolase_3 PF07859.13 ACL95848.1 - 3e-19 69.7 3.0 3.4e-16 59.7 1.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ACL95848.1 - 1e-12 48.0 0.0 4e-12 46.1 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 ACL95848.1 - 1.8e-11 43.6 0.0 2.9e-08 33.1 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Hydrolase_4 PF12146.8 ACL95848.1 - 0.00033 20.0 0.1 0.29 10.4 0.0 2.7 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 ACL95848.1 - 0.0017 17.3 0.0 0.0025 16.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 ACL95848.1 - 0.0022 17.0 0.0 0.0033 16.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Esterase_phd PF10503.9 ACL95848.1 - 0.0032 17.0 2.8 0.011 15.3 2.8 1.8 1 1 0 1 1 1 1 Esterase PHB depolymerase DLH PF01738.18 ACL95848.1 - 0.0034 17.0 1.0 0.058 12.9 1.0 2.6 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 ACL95848.1 - 0.0038 17.9 17.0 0.0038 17.9 17.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ACL95848.1 - 0.11 12.1 0.1 0.29 10.7 0.1 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF2235 PF09994.9 ACL95848.1 - 0.23 10.8 0.0 0.36 10.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) AMP-binding PF00501.28 ACL95849.1 - 3.5e-75 253.2 0.0 4.1e-75 253.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ACL95849.1 - 0.0002 22.3 0.0 0.00047 21.1 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DAHP_synth_2 PF01474.16 ACL95850.1 - 6.2e-200 664.3 0.0 7e-200 664.1 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family DUF4271 PF14093.6 ACL95851.1 - 0.021 14.7 0.0 8.5 6.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) Pyr_redox_2 PF07992.14 ACL95852.1 - 8.1e-64 215.7 1.2 1e-63 215.4 1.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ACL95852.1 - 2.8e-31 108.0 0.1 1.2e-30 106.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 ACL95852.1 - 3.7e-19 69.1 3.1 1.3e-18 67.3 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ACL95852.1 - 1.8e-14 53.7 0.2 1.3e-12 47.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ACL95852.1 - 3.8e-06 25.9 2.2 0.015 14.1 0.0 3.0 3 0 0 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.7 ACL95852.1 - 5e-05 22.8 0.3 9.2e-05 22.0 0.3 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 ACL95852.1 - 0.0054 15.9 0.4 0.0054 15.9 0.4 2.4 2 1 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 ACL95852.1 - 0.0069 15.7 3.2 0.5 9.6 0.6 2.9 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 ACL95852.1 - 0.0099 15.1 0.1 0.034 13.3 0.0 1.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.18 ACL95852.1 - 0.011 15.6 0.8 8.9 6.1 0.0 3.2 4 0 0 4 4 4 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 ACL95852.1 - 0.022 14.0 0.1 0.045 13.0 0.1 1.6 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 ACL95852.1 - 0.084 11.9 8.0 0.4 9.7 4.4 2.8 3 0 0 3 3 3 0 FAD binding domain XdhC_C PF13478.6 ACL95852.1 - 0.14 12.7 0.1 23 5.5 0.0 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain DAO PF01266.24 ACL95852.1 - 6.2 6.3 12.9 8.1 5.9 0.0 3.5 2 1 2 4 4 4 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ACL95852.1 - 7.6 5.7 9.3 12 5.1 0.0 3.2 3 0 0 3 3 3 0 FAD binding domain Rib_5-P_isom_A PF06026.14 ACL95853.1 - 5.8e-57 192.0 0.0 7.2e-57 191.8 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 ACL95853.1 - 8.3e-06 25.8 0.5 4.6e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 DeoR C terminal sensor domain Sugar-bind PF04198.13 ACL95853.1 - 0.04 13.0 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain NTP_transf_3 PF12804.7 ACL95854.1 - 1.1e-22 81.1 2.2 2.3e-22 80.1 2.2 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 ACL95854.1 - 3.9e-22 77.1 11.7 7e-09 35.1 0.0 4.7 2 1 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) IspD PF01128.19 ACL95854.1 - 5.1e-10 39.5 0.2 8.4e-10 38.8 0.2 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transferase PF00483.23 ACL95854.1 - 6.5e-08 32.5 0.0 9.2e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.6 ACL95854.1 - 7.1e-07 28.9 9.3 3.8e-06 26.6 0.1 4.1 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.19 ACL95854.1 - 0.025 14.5 0.0 0.053 13.4 0.0 1.5 1 1 0 1 1 1 0 Cytidylyltransferase HAD_2 PF13419.6 ACL95855.1 - 7.8e-28 97.8 0.0 9.2e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ACL95855.1 - 3.9e-22 79.6 0.9 5.8e-22 79.0 0.9 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ACL95855.1 - 1.9e-11 44.7 0.2 2.6e-11 44.3 0.2 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ACL95855.1 - 5.9e-09 35.9 0.3 1.1e-08 35.0 0.3 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 ACL95855.1 - 9.4e-05 22.5 0.0 0.00093 19.3 0.0 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DrsE PF02635.15 ACL95855.1 - 0.13 12.7 0.1 10 6.6 0.0 2.3 2 0 0 2 2 2 0 DsrE/DsrF-like family Hydrolase_3 PF08282.12 ACL95855.1 - 0.34 10.6 0.9 8.3 6.1 0.4 2.7 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase adh_short PF00106.25 ACL95856.1 - 5.7e-38 130.3 1.2 8.2e-38 129.8 1.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ACL95856.1 - 8.4e-26 91.0 4.3 1.2e-25 90.4 4.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ACL95856.1 - 1.2e-07 31.9 0.6 1.6e-07 31.4 0.6 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ACL95856.1 - 1.7e-06 28.0 0.7 3.3e-06 27.1 0.7 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ACL95856.1 - 0.00032 20.2 0.1 0.00056 19.4 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 ACL95856.1 - 0.054 13.0 0.3 0.098 12.2 0.3 1.4 1 0 0 1 1 1 0 NmrA-like family TrkA_N PF02254.18 ACL95856.1 - 0.075 13.3 1.1 0.12 12.6 0.2 1.7 2 0 0 2 2 2 0 TrkA-N domain ChuX_HutX PF06228.13 ACL95856.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Haem utilisation ChuX/HutX Glyco_hydro_3_C PF01915.22 ACL95856.1 - 0.18 11.7 0.3 0.53 10.2 0.2 1.7 1 1 1 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain SnoaL_2 PF12680.7 ACL95857.1 - 1.4e-13 51.3 0.5 1.7e-13 51.1 0.5 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 ACL95857.1 - 2.2e-07 30.7 0.2 7.3e-07 29.0 0.2 1.7 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DUF4440 PF14534.6 ACL95857.1 - 3.2e-05 24.3 0.2 5.1e-05 23.6 0.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) LEH PF07858.12 ACL95857.1 - 0.00065 19.8 0.3 0.0009 19.3 0.3 1.2 1 0 0 1 1 1 1 Limonene-1,2-epoxide hydrolase catalytic domain NTF2 PF02136.20 ACL95857.1 - 0.15 12.6 0.0 0.24 12.0 0.0 1.4 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain GST_N PF02798.20 ACL95859.1 - 3.1e-12 46.7 0.0 6e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ACL95859.1 - 2.4e-08 34.3 0.0 4.6e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ACL95859.1 - 0.0019 18.5 0.0 0.0036 17.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ACL95859.1 - 0.005 16.8 0.9 0.012 15.6 0.9 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ACL95859.1 - 0.014 15.6 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 ACL95859.1 - 0.085 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Zein PF01559.16 ACL95860.1 - 0.081 12.5 0.2 0.08 12.5 0.2 1.1 1 0 0 1 1 1 0 Zein seed storage protein GST_N_4 PF17172.4 ACL95861.2 - 3.7e-21 75.7 0.0 6.1e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 ACL95861.2 - 2.6e-15 56.0 0.0 4.4e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 ACL95861.2 - 2.5e-07 31.0 0.0 4.8e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_3 PF13417.6 ACL95861.2 - 0.0026 18.1 0.0 0.012 16.1 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ACL95861.2 - 0.0038 17.2 0.5 0.011 15.7 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ACL95861.2 - 0.047 13.9 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain HTH_11 PF08279.12 ACL95862.1 - 3.1e-14 52.6 0.1 5.9e-14 51.8 0.1 1.5 1 0 0 1 1 1 1 HTH domain WYL PF13280.6 ACL95862.1 - 2.7e-09 37.3 0.8 4.5e-09 36.6 0.8 1.4 1 0 0 1 1 1 1 WYL domain HTH_IclR PF09339.10 ACL95862.1 - 0.0016 18.2 0.2 0.0031 17.3 0.2 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_20 PF12840.7 ACL95862.1 - 0.0027 17.7 0.0 0.0052 16.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_DeoR PF08220.12 ACL95862.1 - 0.017 14.8 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain TetR_N PF00440.23 ACL95862.1 - 0.11 12.3 0.1 0.36 10.7 0.1 1.9 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family Peptidase_S9 PF00326.21 ACL95863.1 - 1.6e-12 47.3 0.2 2.1e-11 43.7 0.2 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 ACL95863.1 - 5.6e-11 42.7 0.8 1e-09 38.6 0.8 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 ACL95863.1 - 8.4e-09 35.3 0.5 1.1e-06 28.4 0.2 2.5 2 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 ACL95863.1 - 1e-06 29.6 7.5 2.1e-06 28.5 7.5 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 ACL95863.1 - 0.00056 19.8 0.0 0.69 9.7 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 ACL95863.1 - 0.001 18.4 0.2 0.61 9.3 0.1 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 BAAT_C PF08840.11 ACL95863.1 - 0.019 14.9 0.0 2.5 8.0 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 ACL95863.1 - 0.031 13.9 0.0 1.7 8.1 0.1 2.2 1 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Esterase_phd PF10503.9 ACL95863.1 - 0.043 13.3 0.3 0.091 12.2 0.3 1.5 1 0 0 1 1 1 0 Esterase PHB depolymerase DUF2920 PF11144.8 ACL95863.1 - 0.11 11.7 0.0 0.26 10.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Abhydrolase_1 PF00561.20 ACL95863.1 - 0.16 11.6 0.0 13 5.4 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold COesterase PF00135.28 ACL95863.1 - 0.31 9.9 0.1 0.41 9.5 0.1 1.2 1 0 0 1 1 1 0 Carboxylesterase family SpoU_methylase PF00588.19 ACL95864.1 - 5.4e-26 91.5 0.0 7e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 ACL95864.1 - 0.08 13.2 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding MFS_1 PF07690.16 ACL95865.1 - 5.2e-45 153.9 55.4 1.2e-34 119.8 32.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ACL95865.1 - 2.7e-14 52.6 24.9 1.9e-07 30.0 6.3 3.5 2 2 1 3 3 3 3 MFS/sugar transport protein Sugar_tr PF00083.24 ACL95865.1 - 4.1e-05 22.6 17.0 0.00025 20.0 2.1 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.13 ACL95865.1 - 0.00037 19.0 17.7 0.015 13.7 7.8 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector Hydantoinase_B PF02538.14 ACL95865.1 - 0.17 10.2 0.1 0.25 9.7 0.1 1.2 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase Peripla_BP_3 PF13377.6 ACL95866.1 - 1.1e-41 142.9 0.1 3.5e-40 138.0 0.0 2.1 2 0 0 2 2 2 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 ACL95866.1 - 7.1e-23 81.4 0.0 9.7e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 ACL95866.1 - 1.5e-18 66.3 0.3 3.2e-18 65.2 0.3 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 ACL95866.1 - 3.8e-13 49.6 0.0 8.5e-13 48.5 0.0 1.5 1 1 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_6 PF13458.6 ACL95866.1 - 6.5e-06 26.0 0.0 1.4e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 Periplasmic binding protein HTH_3 PF01381.22 ACL95866.1 - 0.018 15.1 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix HTH_31 PF13560.6 ACL95866.1 - 0.024 15.0 0.5 0.13 12.6 0.0 2.6 2 2 0 2 2 2 0 Helix-turn-helix domain MCPsignal PF00015.21 ACL95867.2 - 2.5e-46 157.6 33.8 2.3e-45 154.5 20.0 3.2 3 1 0 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Protoglobin PF11563.8 ACL95867.2 - 6.7e-37 126.8 0.8 1.3e-36 125.9 0.1 1.9 2 0 0 2 2 2 1 Protoglobin DUF948 PF06103.11 ACL95867.2 - 0.00025 21.2 14.6 0.045 14.0 0.3 4.4 2 2 2 4 4 4 2 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.9 ACL95867.2 - 0.0012 19.0 4.5 1 9.7 0.1 4.2 3 1 1 4 4 4 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_I PF06008.14 ACL95867.2 - 0.0015 18.3 2.6 0.0015 18.3 2.6 2.5 2 0 0 2 2 2 1 Laminin Domain I DUF1664 PF07889.12 ACL95867.2 - 0.041 13.9 7.6 2.9 8.0 1.4 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) ALIX_LYPXL_bnd PF13949.6 ACL95867.2 - 0.055 12.8 9.6 1 8.6 1.3 2.6 1 1 1 2 2 2 0 ALIX V-shaped domain binding to HIV Thiamine_BP PF01910.17 ACL95867.2 - 0.07 13.0 0.2 0.35 10.8 0.2 2.2 1 0 0 1 1 1 0 Thiamine-binding protein Sec8_exocyst PF04048.14 ACL95867.2 - 0.072 13.0 4.3 5.2 7.0 1.2 3.0 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain NPV_P10 PF05531.12 ACL95867.2 - 0.074 13.5 7.4 1.9 9.0 0.1 4.0 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein HAMP PF00672.25 ACL95867.2 - 0.092 13.1 4.0 0.17 12.3 0.1 3.5 2 2 1 3 3 3 0 HAMP domain IFT57 PF10498.9 ACL95867.2 - 0.16 10.9 2.1 0.33 9.9 0.1 2.1 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Seryl_tRNA_N PF02403.22 ACL95867.2 - 0.18 12.0 12.9 0.46 10.7 0.1 4.0 3 2 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Peptidase_S41_N PF11918.8 ACL95867.2 - 0.22 11.8 0.1 0.22 11.8 0.1 2.7 3 0 0 3 3 3 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP TMPIT PF07851.13 ACL95867.2 - 0.27 10.4 2.4 0.71 9.1 0.3 2.2 3 0 0 3 3 3 0 TMPIT-like protein FlgN PF05130.12 ACL95867.2 - 2.4 8.7 21.2 1 9.8 1.3 3.8 2 1 2 4 4 4 0 FlgN protein Tweety PF04906.13 ACL95867.2 - 2.6 6.6 5.2 2 7.0 0.4 2.3 2 0 0 2 2 2 0 Tweety YkyA PF10368.9 ACL95867.2 - 5.1 6.7 8.2 2.2 7.9 1.6 2.6 3 0 0 3 3 3 0 Putative cell-wall binding lipoprotein Laminin_II PF06009.12 ACL95867.2 - 5.6 7.0 13.6 30 4.6 1.1 3.3 1 1 2 3 3 3 0 Laminin Domain II MlaE PF02405.16 ACL95868.1 - 4.5e-66 222.6 20.9 5.6e-66 222.2 20.9 1.1 1 0 0 1 1 1 1 Permease MlaE STAS_2 PF13466.6 ACL95868.1 - 4.1e-06 27.0 2.5 1e-05 25.8 2.5 1.7 1 0 0 1 1 1 1 STAS domain FtsX PF02687.21 ACL95868.1 - 3.6 8.1 21.6 6.3 7.3 9.3 3.0 1 1 1 2 2 2 0 FtsX-like permease family ABC_tran PF00005.27 ACL95869.1 - 2.2e-30 106.0 0.0 2.8e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ACL95869.1 - 3.8e-07 30.2 1.6 8.1e-05 22.6 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ACL95869.1 - 0.0036 16.8 1.4 0.58 9.6 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ACL95869.1 - 0.0037 17.0 0.2 0.0068 16.1 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 ACL95869.1 - 0.013 14.9 0.1 0.069 12.5 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 ACL95869.1 - 0.074 12.9 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase T2SSE PF00437.20 ACL95869.1 - 0.079 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 ACL95869.1 - 0.095 13.1 0.6 0.19 12.1 0.6 1.6 1 1 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 ACL95869.1 - 0.18 10.9 0.2 0.29 10.3 0.2 1.2 1 0 0 1 1 1 0 NB-ARC domain Dynamin_N PF00350.23 ACL95869.1 - 0.36 10.9 0.8 0.56 10.2 0.8 1.2 1 0 0 1 1 1 0 Dynamin family MlaD PF02470.20 ACL95870.1 - 1.1e-14 54.4 0.9 1.1e-14 54.4 0.9 1.7 2 0 0 2 2 2 1 MlaD protein BLOC1_2 PF10046.9 ACL95870.1 - 0.00012 22.3 2.2 0.0069 16.7 0.8 2.5 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Syntaxin-6_N PF09177.11 ACL95870.1 - 0.0037 17.8 2.2 0.53 10.9 0.3 3.0 1 1 2 3 3 3 1 Syntaxin 6, N-terminal Spectrin PF00435.21 ACL95870.1 - 0.009 16.5 0.7 0.017 15.6 0.7 1.5 1 0 0 1 1 1 1 Spectrin repeat Sec8_exocyst PF04048.14 ACL95870.1 - 0.061 13.2 1.1 0.36 10.7 0.9 2.1 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain Laminin_II PF06009.12 ACL95870.1 - 0.096 12.7 4.0 0.32 11.0 3.6 1.9 1 1 1 2 2 2 0 Laminin Domain II FlgN PF05130.12 ACL95870.1 - 0.11 12.9 3.7 0.26 11.8 3.2 1.9 1 1 0 1 1 1 0 FlgN protein HisKA_3 PF07730.13 ACL95870.1 - 0.26 11.8 6.0 3.1 8.4 0.4 3.4 2 1 1 3 3 3 0 Histidine kinase DUF1664 PF07889.12 ACL95870.1 - 0.31 11.1 1.9 1.2 9.2 1.2 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 ACL95870.1 - 0.57 9.5 8.0 0.094 12.0 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF2203 PF09969.9 ACL95870.1 - 0.64 10.8 2.5 21 5.8 2.3 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DASH_Duo1 PF08651.10 ACL95870.1 - 1.2 8.9 4.1 14 5.6 0.6 2.8 2 1 1 3 3 3 0 DASH complex subunit Duo1 DUF948 PF06103.11 ACL95870.1 - 3.3 8.0 13.9 0.19 12.0 3.4 3.2 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) ABC_trans_aux PF03886.13 ACL95871.1 - 1.4e-13 50.7 1.1 1.9e-13 50.3 1.1 1.2 1 0 0 1 1 1 1 ABC-type transport auxiliary lipoprotein component NUDIX PF00293.28 ACL95872.1 - 2.1e-07 31.1 0.5 0.0012 18.9 0.2 2.9 2 1 0 2 2 2 2 NUDIX domain DUF2336 PF10098.9 ACL95873.1 - 8e-79 264.8 2.7 8e-79 264.8 2.7 1.9 2 0 0 2 2 2 1 Uncharacterised protein conserved in bacteria (DUF2336) SMP_2 PF10144.9 ACL95873.1 - 0.1 12.3 0.2 0.18 11.4 0.2 1.4 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin Helicase_C_3 PF13625.6 ACL95873.1 - 0.2 11.8 2.8 0.49 10.5 0.2 2.6 2 1 0 2 2 2 0 Helicase conserved C-terminal domain HTH_IclR PF09339.10 ACL95873.1 - 0.69 9.8 3.3 19 5.2 0.0 3.3 4 0 0 4 4 4 0 IclR helix-turn-helix domain HATPase_c PF02518.26 ACL95874.1 - 3.2e-25 88.8 0.0 5.1e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ACL95874.1 - 7.3e-18 64.8 0.1 1.4e-17 63.8 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ACL95874.1 - 1.4e-06 28.3 1.0 1.6e-05 24.8 0.2 3.1 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 ACL95874.1 - 0.00017 21.6 0.1 0.00045 20.2 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 ACL95874.1 - 0.048 13.5 0.0 0.083 12.7 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF368 PF04018.13 ACL95874.1 - 0.16 11.6 2.9 0.24 11.0 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF368) DUF3310 PF11753.8 ACL95874.1 - 0.24 11.6 0.0 0.49 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknwon function (DUF3310) BTP PF05232.12 ACL95874.1 - 1.2 9.3 9.4 15 5.7 0.0 2.6 2 0 0 2 2 2 0 Chlorhexidine efflux transporter CoA_transf_3 PF02515.17 ACL95875.1 - 3.7e-101 338.9 0.8 4.2e-101 338.7 0.8 1.0 1 0 0 1 1 1 1 CoA-transferase family III SLT PF01464.20 ACL95876.1 - 1.2e-06 28.1 0.0 2.1e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase SLT domain Phage_lysozyme2 PF18013.1 ACL95876.1 - 0.0023 17.9 0.7 0.0051 16.8 0.0 1.8 2 1 0 2 2 2 1 Phage tail lysozyme MoeA_C PF03454.15 ACL95876.1 - 0.17 12.1 0.6 0.65 10.2 0.1 2.1 2 0 0 2 2 2 0 MoeA C-terminal region (domain IV) TonB_C PF03544.14 ACL95877.1 - 8.5e-18 64.6 0.0 1.3e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal Acyl-CoA_dh_1 PF00441.24 ACL95878.1 - 2e-36 125.5 1.8 2e-36 125.5 1.8 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ACL95878.1 - 1.9e-25 89.7 1.5 2.1e-25 89.6 0.2 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ACL95878.1 - 2.9e-19 69.0 0.0 5.3e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ACL95878.1 - 4.8e-15 56.0 2.8 8.7e-15 55.2 2.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Nudix_N PF12535.8 ACL95878.1 - 0.1 12.2 0.2 7.1 6.3 0.0 2.5 2 0 0 2 2 2 0 Hydrolase of X-linked nucleoside diphosphate N terminal DAO PF01266.24 ACL95879.1 - 1.9e-34 119.8 6.2 7.6e-34 117.8 6.2 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ACL95879.1 - 5.1e-05 23.4 0.0 0.00013 22.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 ACL95879.1 - 0.00013 21.9 0.0 0.00018 21.4 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 ACL95879.1 - 0.00058 19.5 0.2 0.001 18.7 0.2 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 ACL95879.1 - 0.00086 18.7 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 ACL95879.1 - 0.0015 18.7 0.0 0.0025 18.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.6 ACL95879.1 - 0.0017 18.8 0.4 0.041 14.4 0.0 2.5 3 0 0 3 3 3 1 XdhC Rossmann domain NAD_binding_9 PF13454.6 ACL95879.1 - 0.0027 17.7 0.3 0.2 11.6 0.1 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding ThiF PF00899.21 ACL95879.1 - 0.0045 16.4 0.1 0.0066 15.8 0.1 1.2 1 0 0 1 1 1 1 ThiF family Pyr_redox_2 PF07992.14 ACL95879.1 - 0.014 14.6 0.1 0.073 12.3 0.1 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ACL95879.1 - 0.018 14.1 0.1 0.029 13.5 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_Gly3P_dh_N PF01210.23 ACL95879.1 - 0.041 13.9 0.0 0.066 13.2 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 ACL95879.1 - 0.047 14.3 0.0 0.09 13.4 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent LPD7 PF18821.1 ACL95879.1 - 0.049 13.7 0.0 5.3 7.2 0.0 2.4 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 7 UDPG_MGDP_dh_N PF03721.14 ACL95879.1 - 0.071 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 ACL95879.1 - 0.083 13.5 0.0 0.18 12.4 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 ACL95879.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain HTH_3 PF01381.22 ACL95880.1 - 1.8e-12 47.1 0.1 2.3e-12 46.7 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 ACL95880.1 - 1.3e-10 41.4 0.1 1.3e-10 41.4 0.1 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 ACL95880.1 - 4.6e-10 39.4 0.0 6.3e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 ACL95880.1 - 0.0031 17.3 0.2 0.0054 16.6 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 ACL95880.1 - 0.024 14.6 0.1 0.041 13.8 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Pou PF00157.17 ACL95880.1 - 0.025 14.5 0.1 0.051 13.6 0.1 1.4 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain HTH_26 PF13443.6 ACL95880.1 - 0.035 14.5 0.0 0.056 13.9 0.0 1.3 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_23 PF13384.6 ACL95880.1 - 0.036 13.9 0.0 0.036 13.9 0.0 1.9 2 1 0 2 2 2 0 Homeodomain-like domain MqsA_antitoxin PF15731.5 ACL95880.1 - 0.11 12.6 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA YdaS_antitoxin PF15943.5 ACL95880.1 - 0.16 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Bac_DNA_binding PF00216.21 ACL95881.1 - 3.2e-29 101.0 0.5 3.5e-29 100.8 0.5 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 ACL95881.1 - 3.4e-06 27.2 0.0 3.5e-06 27.1 0.0 1.0 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_euk_1 PF14908.6 ACL95881.1 - 0.0004 20.5 0.0 0.00043 20.4 0.0 1.1 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 HU-DNA_bdg PF14848.6 ACL95881.1 - 0.00058 19.9 0.1 0.0016 18.5 0.1 1.7 1 1 0 1 1 1 1 DNA-binding domain HU-CCDC81_euk_2 PF18289.1 ACL95881.1 - 0.0097 16.0 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 HU-CCDC81_bac_1 PF18174.1 ACL95881.1 - 0.016 15.1 0.0 0.032 14.1 0.0 1.5 1 1 0 1 1 1 0 CCDC81-like prokaryotic HU domain 1 HU-CCDC81_bac_2 PF18175.1 ACL95881.1 - 0.063 13.1 0.0 0.14 12.0 0.0 1.5 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 2 Radical_SAM PF04055.21 ACL95882.1 - 6.6e-07 29.8 0.0 3.1e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily HHH_5 PF14520.6 ACL95882.1 - 0.0097 16.5 0.0 0.024 15.2 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_3 PF12836.7 ACL95882.1 - 0.083 13.2 0.0 0.28 11.5 0.0 1.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF4130 PF13566.6 ACL95883.1 - 2e-45 154.4 2.0 3.3e-45 153.7 2.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4130 UDG PF03167.19 ACL95883.1 - 9.9e-31 106.8 0.0 2.3e-30 105.7 0.0 1.6 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily TonB_C PF03544.14 ACL95884.1 - 1.6e-15 57.3 0.0 2.5e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Gram-negative bacterial TonB protein C-terminal ExbD PF02472.16 ACL95885.1 - 1e-28 100.1 0.0 1.1e-28 100.0 0.0 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR MotA_ExbB PF01618.16 ACL95886.1 - 7.4e-30 103.3 2.3 1.7e-29 102.2 2.3 1.6 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family KleE PF17394.2 ACL95886.1 - 0.029 14.6 1.5 0.029 14.6 1.5 2.0 1 1 1 2 2 2 0 Uncharacterized KleE stable inheritance protein adh_short PF00106.25 ACL95887.1 - 4.9e-42 143.6 0.3 6.5e-42 143.2 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ACL95887.1 - 2.9e-26 92.5 1.8 3.8e-26 92.1 1.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ACL95887.1 - 8.6e-17 61.6 0.2 1.2e-16 61.2 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ACL95887.1 - 6.9e-08 32.2 0.3 1.6e-07 31.1 0.3 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ACL95887.1 - 1.8e-05 24.8 2.6 3e-05 24.0 2.6 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 ACL95887.1 - 0.001 19.3 0.1 0.0014 18.9 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 ACL95887.1 - 0.0029 17.1 0.0 0.0042 16.5 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase F420_oxidored PF03807.17 ACL95887.1 - 0.0042 17.6 1.0 0.0097 16.5 0.2 2.0 3 0 0 3 3 2 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 ACL95887.1 - 0.0043 16.2 0.0 0.0061 15.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Glyco_transf_4 PF13439.6 ACL95887.1 - 0.0072 16.3 0.7 3.1 7.8 0.1 3.1 2 1 0 3 3 3 1 Glycosyltransferase Family 4 Glyco_tran_WecB PF03808.13 ACL95887.1 - 0.01 15.8 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family TetR_C_31 PF17940.1 ACL95887.1 - 0.097 12.9 7.4 0.048 13.9 4.6 2.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF2141 PF09912.9 ACL95888.2 - 3.4e-27 94.6 0.0 4e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2141) TetR_C_33 PF13305.6 ACL95889.1 - 4e-15 56.4 3.1 4e-15 56.4 3.1 2.0 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ACL95889.1 - 6.3e-11 41.9 0.0 1.7e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_50 PF18024.1 ACL95889.1 - 0.0039 16.8 0.1 0.011 15.3 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 ACL95889.1 - 0.035 14.4 3.5 0.038 14.3 1.2 2.3 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_38 PF13936.6 ACL95889.1 - 0.08 12.7 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 ACL95889.1 - 0.12 12.2 1.4 0.43 10.5 0.0 2.3 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain YacG PF03884.14 ACL95890.1 - 6.2e-15 54.7 1.4 8.4e-15 54.2 1.4 1.2 1 0 0 1 1 1 1 DNA gyrase inhibitor YacG DUF2116 PF09889.9 ACL95890.1 - 0.046 13.7 0.4 0.061 13.3 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) zf-Di19 PF05605.12 ACL95890.1 - 0.056 13.7 2.2 2.8 8.3 0.7 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C6H2 PF15801.5 ACL95890.1 - 0.064 13.6 0.9 0.076 13.3 0.9 1.2 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding RNase_E_G PF10150.9 ACL95891.1 - 7.4e-17 61.6 0.0 1e-16 61.2 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease E/G family Maf PF02545.14 ACL95892.1 - 2.5e-47 160.8 0.0 2.8e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein eIF-1a PF01176.19 ACL95893.2 - 2.8e-27 94.3 0.0 3.1e-27 94.2 0.0 1.0 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 RsgA_N PF16745.5 ACL95893.2 - 0.0062 16.3 0.0 0.0078 15.9 0.0 1.2 1 0 0 1 1 1 1 RsgA N-terminal domain Polo_box_3 PF18544.1 ACL95893.2 - 0.12 13.0 0.0 0.13 13.0 0.0 1.2 1 0 0 1 1 1 0 Polo box domain LMWPc PF01451.21 ACL95894.1 - 1.1e-16 61.5 0.0 1.2e-16 61.3 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase MukB_hinge PF16330.5 ACL95894.1 - 0.038 13.7 0.1 0.048 13.3 0.1 1.1 1 0 0 1 1 1 0 MukB hinge domain UPF0262 PF06793.12 ACL95895.1 - 2.7e-68 228.9 0.0 3e-68 228.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0262) Histidinol_dh PF00815.20 ACL95896.1 - 5.6e-159 529.5 3.2 6.8e-159 529.2 3.2 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase PNP_phzG_C PF10590.9 ACL95896.1 - 0.1 12.7 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Transp_cyt_pur PF02133.15 ACL95897.1 - 9.7e-116 387.1 42.7 1.1e-115 386.9 42.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2948 PF11164.8 ACL95899.2 - 6.7e-51 171.9 0.1 7.5e-51 171.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2948) TetR_C_22 PF17928.1 ACL95899.2 - 0.013 15.8 0.4 6.5 7.1 0.1 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain EPSP_synthase PF00275.20 ACL95900.1 - 3e-103 345.7 0.4 3.4e-103 345.5 0.4 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) LysR_substrate PF03466.20 ACL95902.1 - 8.7e-30 103.6 2.3 1.3e-29 103.1 2.3 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 ACL95902.1 - 5.6e-21 74.2 1.0 5.6e-21 74.2 1.0 1.9 2 0 0 2 2 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_20 PF12840.7 ACL95902.1 - 0.0021 18.0 0.3 0.0081 16.2 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 ACL95902.1 - 0.0034 16.7 0.0 0.0085 15.5 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 MarR_2 PF12802.7 ACL95902.1 - 0.0054 16.6 0.1 0.019 14.8 0.1 2.0 1 0 0 1 1 1 1 MarR family HTH_28 PF13518.6 ACL95902.1 - 0.006 16.7 0.1 0.015 15.4 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_8 PF02954.19 ACL95902.1 - 0.014 15.2 0.0 0.097 12.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family HTH_5 PF01022.20 ACL95902.1 - 0.017 14.9 0.0 0.045 13.6 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 ACL95902.1 - 0.033 13.7 0.0 0.064 12.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_29 PF13551.6 ACL95902.1 - 0.042 13.9 0.0 0.08 13.0 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HTH_30 PF13556.6 ACL95902.1 - 0.051 13.4 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain HTH_23 PF13384.6 ACL95902.1 - 0.056 13.3 0.1 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain HTH_AsnC-type PF13404.6 ACL95902.1 - 0.071 12.9 0.6 0.21 11.4 0.1 2.2 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain MarR PF01047.22 ACL95902.1 - 0.073 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_IclR PF09339.10 ACL95902.1 - 0.08 12.8 1.5 0.58 10.0 0.0 3.0 3 0 0 3 3 3 0 IclR helix-turn-helix domain ADH_zinc_N_2 PF13602.6 ACL95903.1 - 9.2e-22 78.5 0.0 1.5e-21 77.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ACL95903.1 - 6.1e-14 52.1 0.6 1.7e-13 50.7 0.1 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ACL95903.1 - 6.7e-05 22.7 0.0 0.00059 19.7 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 ACL95903.1 - 0.013 14.8 0.1 0.02 14.2 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.21 ACL95903.1 - 0.043 13.5 0.0 0.062 13.0 0.0 1.1 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase MFS_1 PF07690.16 ACL95904.1 - 7.6e-38 130.3 49.5 7.6e-38 130.3 49.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ACL95904.1 - 0.00021 20.7 14.2 0.00021 20.7 14.2 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB SpoIIIAC PF06686.11 ACL95904.1 - 2.2 8.5 5.9 0.22 11.7 0.5 2.1 2 0 0 2 2 2 0 Stage III sporulation protein AC/AD protein family Peripla_BP_3 PF13377.6 ACL95905.1 - 7.1e-30 104.5 2.8 7.1e-30 104.5 2.8 1.9 2 0 0 2 2 2 1 Periplasmic binding protein-like domain LacI PF00356.21 ACL95905.1 - 2.2e-19 69.0 0.4 4.3e-19 68.0 0.4 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_1 PF00532.21 ACL95905.1 - 4.3e-18 65.7 0.1 5.1e-18 65.5 0.1 1.1 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Peripla_BP_4 PF13407.6 ACL95905.1 - 7.3e-17 61.8 0.0 9.6e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain HTH_31 PF13560.6 ACL95905.1 - 0.00093 19.5 3.6 0.00094 19.5 0.2 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 ACL95905.1 - 0.0018 18.0 0.0 0.0074 16.1 0.0 2.0 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4 PF04545.16 ACL95905.1 - 0.0048 16.4 0.4 0.013 15.0 0.0 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_3 PF01381.22 ACL95905.1 - 0.0071 16.4 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_38 PF13936.6 ACL95905.1 - 0.008 15.9 0.3 0.023 14.4 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain CENP-B_N PF04218.13 ACL95905.1 - 0.016 14.8 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_7 PF02796.15 ACL95905.1 - 0.017 15.2 0.0 0.048 13.7 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_Tnp_ISL3 PF13542.6 ACL95905.1 - 0.024 14.1 0.3 0.057 12.8 0.3 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 TetR_N PF00440.23 ACL95905.1 - 0.027 14.2 0.2 0.027 14.2 0.2 2.4 3 0 0 3 3 3 0 Bacterial regulatory proteins, tetR family HTH_Crp_2 PF13545.6 ACL95905.1 - 0.053 13.5 0.3 0.15 12.1 0.1 1.9 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_24 PF13412.6 ACL95905.1 - 0.087 12.4 0.1 0.28 10.8 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding GerE PF00196.19 ACL95906.1 - 5.8e-09 35.4 0.1 6.7e-09 35.2 0.1 1.1 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Glyco_hydro_39 PF01229.17 ACL95907.1 - 1.6e-97 327.1 0.0 2.1e-97 326.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Cellulase PF00150.18 ACL95907.1 - 1e-05 25.1 0.0 1.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_44 PF12891.7 ACL95907.1 - 0.01 15.8 0.1 0.023 14.7 0.1 1.5 1 1 0 1 1 1 0 Glycoside hydrolase family 44 CarboxypepD_reg PF13620.6 ACL95907.1 - 0.04 14.2 0.0 0.083 13.2 0.0 1.6 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain DLH PF01738.18 ACL95908.1 - 2e-44 151.7 0.0 2.4e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 ACL95908.1 - 2.4e-05 24.4 0.1 0.0029 17.6 0.0 2.4 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 ACL95908.1 - 2.9e-05 23.7 0.3 0.18 11.3 0.0 2.8 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 ACL95908.1 - 0.00064 19.5 0.0 0.0013 18.5 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 ACL95908.1 - 0.0064 15.4 0.0 0.012 14.5 0.0 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_3 PF07859.13 ACL95908.1 - 0.021 14.7 0.4 14 5.5 0.0 3.1 2 1 1 3 3 3 0 alpha/beta hydrolase fold Chlorophyllase PF07224.11 ACL95908.1 - 0.029 13.4 0.0 0.063 12.3 0.0 1.6 1 1 0 1 1 1 0 Chlorophyllase Phage_holin_2_4 PF16082.5 ACL95908.1 - 0.1 12.3 1.0 4.4 7.1 0.2 2.6 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like PAF-AH_p_II PF03403.13 ACL95908.1 - 0.24 9.9 0.0 0.34 9.4 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Asparaginase_2 PF01112.18 ACL95909.2 - 4e-79 265.8 1.6 5.4e-79 265.4 1.6 1.1 1 0 0 1 1 1 1 Asparaginase CutC PF03932.14 ACL95910.1 - 4.1e-85 284.4 0.1 4.8e-85 284.2 0.1 1.0 1 0 0 1 1 1 1 CutC family GSP_synth PF03738.14 ACL95911.1 - 1.1e-143 479.0 0.0 1.2e-143 478.8 0.0 1.0 1 0 0 1 1 1 1 Glutathionylspermidine synthase preATP-grasp PspA_IM30 PF04012.12 ACL95912.1 - 1.8e-63 214.0 24.1 2.1e-63 213.9 24.1 1.0 1 0 0 1 1 1 1 PspA/IM30 family Tropomyosin_1 PF12718.7 ACL95912.1 - 0.0069 16.6 12.6 0.015 15.5 12.6 1.5 1 0 0 1 1 1 1 Tropomyosin like TMF_TATA_bd PF12325.8 ACL95912.1 - 0.036 14.3 15.3 0.14 12.4 10.3 3.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Snf7 PF03357.21 ACL95912.1 - 0.064 12.8 11.5 0.04 13.5 7.9 2.1 1 1 1 2 2 2 0 Snf7 V_ATPase_I PF01496.19 ACL95912.1 - 0.074 11.0 3.0 0.087 10.7 3.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc29 PF17082.5 ACL95912.1 - 0.11 12.3 3.2 0.14 12.0 3.2 1.3 1 0 0 1 1 1 0 Spindle Pole Component 29 Golgin_A5 PF09787.9 ACL95912.1 - 0.19 11.2 13.7 0.042 13.3 10.5 1.4 2 0 0 2 2 2 0 Golgin subfamily A member 5 KELK PF15796.5 ACL95912.1 - 0.26 11.8 7.7 0.64 10.5 0.7 2.7 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PRKG1_interact PF15898.5 ACL95912.1 - 0.46 11.4 12.7 1.1 10.2 2.1 2.3 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain FAA_hydrolase_N PF09298.11 ACL95912.1 - 0.48 10.6 4.9 0.36 11.0 2.1 2.0 1 1 1 2 2 2 0 Fumarylacetoacetase N-terminal FlaC_arch PF05377.11 ACL95912.1 - 0.54 10.7 3.9 1.3 9.5 1.4 2.6 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) APG6_N PF17675.1 ACL95912.1 - 0.56 10.7 21.8 0.12 12.9 4.0 2.8 2 1 1 3 3 3 0 Apg6 coiled-coil region Syntaxin-6_N PF09177.11 ACL95912.1 - 0.61 10.7 7.9 1.9 9.1 6.7 2.3 1 1 0 1 1 1 0 Syntaxin 6, N-terminal RasGAP_C PF03836.15 ACL95912.1 - 0.82 9.8 8.0 0.93 9.6 0.5 2.2 1 1 1 2 2 2 0 RasGAP C-terminus DUF4201 PF13870.6 ACL95912.1 - 0.84 9.3 10.6 0.12 12.1 0.6 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) YabA PF06156.13 ACL95912.1 - 0.87 10.3 8.3 12 6.6 0.3 2.6 1 1 1 2 2 2 0 Initiation control protein YabA Atg14 PF10186.9 ACL95912.1 - 0.88 8.6 11.5 1.2 8.1 11.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FUSC PF04632.12 ACL95912.1 - 1.4 7.4 14.4 1.7 7.1 14.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Spc7 PF08317.11 ACL95912.1 - 2.9 6.7 15.0 3 6.6 13.5 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein UPF0242 PF06785.11 ACL95912.1 - 3.1 7.9 9.9 1.3 9.1 7.5 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus BRE1 PF08647.11 ACL95912.1 - 3.7 7.7 17.9 0.4 10.8 1.9 2.7 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase ATG16 PF08614.11 ACL95912.1 - 6 7.0 21.1 7.3 6.8 5.4 2.8 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF2170 PF09938.9 ACL95913.1 - 8.3e-49 164.8 0.0 1e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2170) FYTT PF07078.11 ACL95913.1 - 0.02 14.2 0.2 0.027 13.8 0.2 1.1 1 0 0 1 1 1 0 Forty-two-three protein DUF2491 PF10679.9 ACL95914.2 - 2.3e-60 203.4 0.0 2.6e-60 203.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2491) DUF350 PF03994.14 ACL95915.1 - 8.4e-22 77.1 14.5 6.5e-12 45.4 1.2 2.6 2 1 1 3 3 3 2 Domain of Unknown Function (DUF350) DUF4199 PF13858.6 ACL95915.1 - 3.1 8.2 10.1 0.24 11.8 2.6 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF4199) VPDSG-CTERM PF18205.1 ACL95915.1 - 3.5 7.6 8.2 4.1 7.3 6.2 2.2 2 0 0 2 2 2 0 VPDSG-CTERM motif DUF1190 PF06693.11 ACL95916.1 - 1.9e-37 129.1 1.7 2.8e-37 128.6 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1190) LMWPc PF01451.21 ACL95918.1 - 4.7e-31 108.1 0.0 5.4e-31 107.9 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Hydantoinase_B PF02538.14 ACL95919.2 - 5.4e-204 678.4 6.6 1e-203 677.4 6.6 1.5 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 ACL95919.2 - 6e-116 386.8 4.6 6e-116 386.8 4.6 1.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 ACL95919.2 - 3.8e-59 199.4 0.3 1.4e-56 191.0 0.0 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region UPF0016 PF01169.19 ACL95920.2 - 3.3e-40 136.3 23.4 2.4e-20 72.6 7.5 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TauE PF01925.19 ACL95920.2 - 0.0058 16.3 16.5 0.013 15.2 2.8 2.2 1 1 1 2 2 2 2 Sulfite exporter TauE/SafE DUF2793 PF10983.8 ACL95921.1 - 9.4e-29 99.1 3.9 1.5e-28 98.5 3.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2793) NMO PF03060.15 ACL95922.1 - 4.9e-22 78.8 0.5 1.2e-20 74.2 0.5 2.3 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 ACL95922.1 - 4.9e-08 32.4 2.2 8.6e-08 31.6 2.1 1.4 1 1 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.14 ACL95922.1 - 0.0045 16.3 0.5 0.0074 15.6 0.5 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 ACL95922.1 - 0.013 14.9 0.1 0.023 14.2 0.1 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein IMPDH PF00478.25 ACL95922.1 - 0.1 11.6 1.6 0.29 10.1 1.6 2.0 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Asparaginase_C PF17763.1 ACL95922.1 - 0.15 12.3 0.0 2.1 8.6 0.0 2.3 1 1 1 2 2 2 0 Glutaminase/Asparaginase C-terminal domain MM_CoA_mutase PF01642.22 ACL95923.1 - 1.8e-87 294.1 0.0 2.5e-87 293.6 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase MM_CoA_mutase PF01642.22 ACL95924.1 - 9e-232 770.2 0.4 9e-232 770.2 0.4 1.3 2 0 0 2 2 2 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 ACL95924.1 - 3.5e-14 52.9 0.5 7e-14 51.9 0.5 1.5 1 0 0 1 1 1 1 B12 binding domain DUF4112 PF13430.6 ACL95925.1 - 1.3e-20 73.6 0.1 1.6e-20 73.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DUF4112 PF13430.6 ACL95926.2 - 2.4e-20 72.8 0.4 3e-20 72.5 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) YbjQ_1 PF01906.17 ACL95927.1 - 2.6e-34 118.0 0.2 2.9e-34 117.8 0.2 1.0 1 0 0 1 1 1 1 Putative heavy-metal-binding DUF4156 PF13698.6 ACL95927.1 - 0.05 13.9 0.1 0.12 12.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4156) Epimerase PF01370.21 ACL95928.1 - 2.5e-56 190.8 0.0 3e-56 190.6 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ACL95928.1 - 8.6e-51 173.3 0.0 1e-50 173.0 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ACL95928.1 - 3.8e-22 78.6 0.0 5.1e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ACL95928.1 - 2.6e-13 49.7 0.0 3.1e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 ACL95928.1 - 1.6e-12 47.2 0.0 3.7e-11 42.7 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 ACL95928.1 - 4.1e-09 36.6 0.0 6.7e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 ACL95928.1 - 5.4e-06 25.8 0.0 0.044 13.0 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.25 ACL95928.1 - 1.1e-05 25.0 0.2 5.6e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 ACL95928.1 - 7.7e-05 22.4 0.1 0.00016 21.4 0.1 1.4 2 0 0 2 2 2 1 NmrA-like family KR PF08659.10 ACL95928.1 - 0.0013 18.6 0.3 0.0034 17.3 0.3 1.7 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 ACL95928.1 - 0.0029 17.9 0.1 0.062 13.6 0.1 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain adh_short_C2 PF13561.6 ACL95928.1 - 0.0098 15.5 0.1 0.031 13.8 0.1 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase UDPG_MGDP_dh_N PF03721.14 ACL95929.1 - 2.1e-65 219.8 0.0 3.6e-65 219.0 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 ACL95929.1 - 2e-39 133.7 0.1 6.4e-39 132.1 0.0 1.9 2 0 0 2 2 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 ACL95929.1 - 7.2e-33 113.2 0.0 2.2e-31 108.4 0.0 2.8 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain F420_oxidored PF03807.17 ACL95929.1 - 4.9e-06 27.0 0.7 3.8 8.1 0.0 4.7 4 2 0 4 4 4 2 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 ACL95929.1 - 0.0011 18.4 0.2 8.4 5.7 0.1 3.3 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 ACL95929.1 - 0.013 15.1 0.0 0.066 12.9 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 ACL95929.1 - 0.015 15.5 0.2 4.5 7.6 0.0 3.8 4 1 0 4 4 4 0 TrkA-N domain Pyr_redox PF00070.27 ACL95929.1 - 0.017 15.7 0.1 0.098 13.2 0.1 2.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 ACL95929.1 - 0.018 14.9 0.1 0.073 13.0 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ACL95929.1 - 0.041 13.2 2.0 0.078 12.3 0.1 2.4 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain GFO_IDH_MocA PF01408.22 ACL95929.1 - 0.049 14.5 0.1 0.72 10.7 0.0 2.8 2 1 1 3 3 3 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_2 PF03446.15 ACL95929.1 - 0.05 13.8 0.0 3.5 7.8 0.0 2.9 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 ACL95930.1 - 7.2e-65 218.1 0.0 1.3e-64 217.3 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 ACL95930.1 - 2.1e-39 133.6 0.1 6.4e-39 132.1 0.0 1.9 2 0 0 2 2 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 ACL95930.1 - 1.6e-32 112.0 0.0 4.8e-31 107.3 0.0 2.8 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain F420_oxidored PF03807.17 ACL95930.1 - 5.7e-06 26.8 0.9 3.9 8.1 0.0 4.7 4 2 0 4 4 4 2 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 ACL95930.1 - 0.0033 16.8 0.2 8.4 5.7 0.1 3.2 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 ACL95930.1 - 0.015 14.9 0.0 0.066 12.9 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 ACL95930.1 - 0.017 15.0 0.1 0.073 13.0 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 ACL95930.1 - 0.019 15.5 0.1 0.098 13.2 0.1 2.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 ACL95930.1 - 0.049 13.9 0.2 4.5 7.6 0.0 3.6 4 1 0 4 4 4 0 TrkA-N domain AlaDh_PNT_C PF01262.21 ACL95930.1 - 0.052 12.8 2.2 0.079 12.2 0.1 2.4 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain GFO_IDH_MocA PF01408.22 ACL95930.1 - 0.081 13.8 0.0 0.73 10.7 0.0 2.6 2 1 1 3 3 3 0 Oxidoreductase family, NAD-binding Rossmann fold GDP_Man_Dehyd PF16363.5 ACL95931.1 - 2e-51 175.4 0.0 8.3e-51 173.3 0.0 2.2 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ACL95931.1 - 3.9e-50 170.6 0.0 4.8e-50 170.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ACL95931.1 - 1.8e-13 50.1 0.0 9.4e-12 44.5 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 ACL95931.1 - 7.3e-13 48.3 0.0 9.5e-12 44.6 0.0 2.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 ACL95931.1 - 7.3e-13 48.3 0.0 9.8e-13 47.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 ACL95931.1 - 1.1e-05 24.7 0.0 3e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 ACL95931.1 - 0.036 13.6 0.2 0.18 11.3 0.2 2.0 1 1 0 1 1 1 0 NmrA-like family Bac_transf PF02397.16 ACL95932.1 - 9e-62 208.0 0.0 1e-61 207.8 0.0 1.0 1 0 0 1 1 1 1 Bacterial sugar transferase HipA_C PF07804.12 ACL95934.1 - 6.2e-13 48.9 0.0 8.3e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 HipA-like C-terminal domain EAL PF00563.20 ACL95934.1 - 0.082 12.4 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 EAL domain OEP PF02321.18 ACL95936.1 - 2.2e-21 76.5 27.5 1.4e-15 57.6 5.6 2.3 2 0 0 2 2 2 2 Outer membrane efflux protein Phenol_MetA_deg PF13557.6 ACL95936.1 - 0.15 12.0 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative MetA-pathway of phenol degradation HlyD_D23 PF16576.5 ACL95937.1 - 4e-18 65.4 0.0 1.1e-12 47.6 0.0 2.2 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 ACL95937.1 - 1.3e-17 64.4 0.0 1.2e-14 54.8 0.1 2.7 1 1 1 2 2 2 2 HlyD family secretion protein GCV_H PF01597.19 ACL95937.1 - 0.0019 18.1 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD PF00529.20 ACL95937.1 - 0.0078 16.1 0.0 0.7 9.8 0.0 2.3 2 1 0 2 2 2 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl_2 PF13533.6 ACL95937.1 - 0.032 14.0 0.0 0.22 11.4 0.0 2.4 1 1 1 2 2 2 0 Biotin-lipoyl like CSD2 PF17876.1 ACL95937.1 - 0.065 13.4 0.0 0.22 11.7 0.0 1.9 2 0 0 2 2 2 0 Cold shock domain Biotin_lipoyl PF00364.22 ACL95937.1 - 0.093 12.6 0.0 0.33 10.8 0.0 2.1 1 0 0 1 1 1 0 Biotin-requiring enzyme RnfC_N PF13375.6 ACL95937.1 - 0.12 12.4 0.0 0.43 10.6 0.0 1.9 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain ACR_tran PF00873.19 ACL95938.3 - 0 1080.2 13.3 0 1080.0 13.3 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MarR_2 PF12802.7 ACL95939.1 - 1.1e-07 31.6 3.7 1.2e-07 31.5 0.4 2.6 3 0 0 3 3 3 1 MarR family MarR PF01047.22 ACL95939.1 - 4.9e-05 23.2 0.0 0.00011 22.1 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.6 ACL95939.1 - 0.00051 20.5 0.3 0.0018 18.7 0.1 1.9 2 1 1 3 3 3 1 Winged helix DNA-binding domain HTH_Crp_2 PF13545.6 ACL95939.1 - 0.0021 18.0 3.2 0.068 13.2 0.2 2.3 1 1 1 2 2 2 2 Crp-like helix-turn-helix domain GntR PF00392.21 ACL95939.1 - 0.012 15.2 1.0 0.036 13.7 0.1 2.2 2 1 0 2 2 2 0 Bacterial regulatory proteins, gntR family TrmB PF01978.19 ACL95939.1 - 0.022 14.6 0.0 0.08 12.8 0.0 1.9 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.6 ACL95939.1 - 0.037 13.6 0.0 0.099 12.2 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding FCD PF07729.12 ACL95940.1 - 3.5e-16 59.8 10.7 6.2e-16 59.0 10.7 1.4 1 0 0 1 1 1 1 FCD domain GntR PF00392.21 ACL95940.1 - 2e-14 52.9 1.0 4.2e-14 51.9 0.6 1.8 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 ACL95940.1 - 0.0051 16.4 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding AbiEi_4 PF13338.6 ACL95940.1 - 0.0093 16.1 0.3 0.0093 16.1 0.3 2.7 3 1 0 3 3 3 1 Transcriptional regulator, AbiEi antitoxin FaeA PF04703.12 ACL95940.1 - 0.051 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 FaeA-like protein HTH_28 PF13518.6 ACL95940.1 - 0.081 13.1 2.3 0.16 12.2 0.1 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain PaaX PF07848.12 ACL95940.1 - 0.11 12.7 0.9 0.34 11.1 0.2 2.3 2 1 0 2 2 2 0 PaaX-like protein Rieske PF00355.26 ACL95941.1 - 1.1e-14 54.1 0.0 2.5e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 ACL95941.1 - 0.18 12.0 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Pheophorbide a oxygenase Fer2 PF00111.27 ACL95942.1 - 1.1e-12 47.7 1.8 2e-12 46.9 1.8 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.21 ACL95942.1 - 0.00077 20.1 0.0 0.031 14.9 0.0 2.5 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Fer2_4 PF13510.6 ACL95942.1 - 0.012 15.6 0.3 0.041 13.9 0.3 1.9 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain NAD_binding_6 PF08030.12 ACL95942.1 - 0.077 13.1 0.0 1.1 9.3 0.1 2.7 3 1 1 4 4 4 0 Ferric reductase NAD binding domain Fer2_3 PF13085.6 ACL95942.1 - 0.17 11.9 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain FAD_binding_6 PF00970.24 ACL95942.1 - 0.18 12.1 0.0 0.65 10.4 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain Abhydrolase_1 PF00561.20 ACL95943.1 - 9.7e-24 84.4 0.2 1.1e-22 80.9 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ACL95943.1 - 1.8e-21 77.8 2.5 2.3e-21 77.4 2.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ACL95943.1 - 6.8e-16 58.3 0.0 1.2e-15 57.4 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 ACL95943.1 - 0.0017 17.1 0.1 0.012 14.4 0.1 1.9 2 0 0 2 2 2 1 Ndr family Peptidase_S9 PF00326.21 ACL95943.1 - 0.0031 17.0 0.2 2 7.9 0.0 2.7 2 1 1 3 3 3 2 Prolyl oligopeptidase family DLH PF01738.18 ACL95943.1 - 0.0081 15.7 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 ACL95943.1 - 0.01 15.6 0.0 3.3 7.4 0.0 2.4 3 0 0 3 3 3 0 Alpha/beta hydrolase family AXE1 PF05448.12 ACL95943.1 - 0.018 13.7 0.2 0.031 12.9 0.2 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 ACL95943.1 - 0.028 14.2 0.0 7.1 6.4 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.20 ACL95943.1 - 0.036 13.7 0.1 0.049 13.3 0.1 1.2 1 0 0 1 1 1 0 Putative esterase DUF2721 PF11026.8 ACL95943.1 - 0.039 13.8 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Abhydrolase_3 PF07859.13 ACL95943.1 - 0.14 12.0 1.8 0.25 11.2 1.6 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold ADH_N PF08240.12 ACL95944.1 - 8e-27 93.3 2.2 1.4e-26 92.5 2.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ACL95944.1 - 4.2e-22 78.5 1.7 7.3e-22 77.7 1.7 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ACL95944.1 - 0.0013 18.0 3.4 0.0021 17.4 3.4 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Aldedh PF00171.22 ACL95945.1 - 1.3e-153 511.8 0.1 1.5e-153 511.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TonB_dep_Rec PF00593.24 ACL95946.1 - 2.8e-46 159.4 17.7 2.8e-46 159.4 17.7 2.0 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 ACL95946.1 - 1.8e-15 57.4 1.6 1.8e-15 57.4 1.6 2.2 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain AraC_binding_2 PF14525.6 ACL95947.1 - 4.8e-31 107.8 8.9 1e-30 106.7 6.2 2.1 1 1 1 2 2 2 1 AraC-binding-like domain HTH_18 PF12833.7 ACL95947.1 - 2.1e-21 76.0 0.1 3.8e-21 75.2 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 ACL95947.1 - 3.8e-12 46.0 0.0 1.9e-07 31.0 0.0 2.6 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_31 PF13560.6 ACL95947.1 - 0.059 13.7 0.5 0.059 13.7 0.5 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain AraC_binding PF02311.19 ACL95947.1 - 0.062 13.2 0.0 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain AMP-binding PF00501.28 ACL95948.1 - 5.5e-85 285.5 0.0 7.7e-85 285.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ACL95948.1 - 5.3e-18 65.8 0.1 1.2e-17 64.6 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ECH_1 PF00378.20 ACL95949.1 - 3.3e-47 160.9 0.0 4.1e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ACL95949.1 - 1e-31 110.7 0.0 5.8e-29 101.6 0.0 1.9 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Aldedh PF00171.22 ACL95950.1 - 7.7e-150 499.4 7.4 8.6e-150 499.3 7.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 ACL95950.1 - 0.0044 16.1 0.2 0.0069 15.5 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) HTH_18 PF12833.7 ACL95951.1 - 1.9e-19 69.7 1.9 2.2e-19 69.5 0.5 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 ACL95951.1 - 4.2e-09 36.3 0.0 1.1e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family Cupin_2 PF07883.11 ACL95951.1 - 3.1e-05 23.6 0.2 6e-05 22.7 0.2 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 ACL95951.1 - 0.0017 18.2 0.1 0.0033 17.3 0.1 1.4 1 1 0 1 1 1 1 AraC-like ligand binding domain FAD_binding_3 PF01494.19 ACL95952.1 - 5.1e-90 302.2 0.0 5.8e-90 302.1 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ACL95952.1 - 1.4e-06 28.5 0.3 4e-06 27.0 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ACL95952.1 - 4.4e-05 22.9 0.0 0.0001 21.7 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ACL95952.1 - 9.8e-05 21.7 0.9 0.00026 20.3 0.6 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ACL95952.1 - 0.00046 19.4 0.4 0.00077 18.7 0.4 1.4 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ACL95952.1 - 0.00091 18.0 0.1 0.0014 17.5 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 ACL95952.1 - 0.00094 18.5 0.1 0.0018 17.6 0.1 1.4 1 0 0 1 1 1 1 Thi4 family ApbA PF02558.16 ACL95952.1 - 0.0024 17.5 0.3 0.0045 16.7 0.3 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DAO PF01266.24 ACL95952.1 - 0.0029 17.2 0.9 0.0092 15.6 0.9 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 ACL95952.1 - 0.0084 16.6 0.4 0.021 15.4 0.4 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ACL95952.1 - 0.019 14.1 0.5 0.035 13.1 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein IlvN PF07991.12 ACL95952.1 - 0.039 13.5 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 ACL95952.1 - 0.055 13.3 0.2 0.099 12.5 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5-nucleotidase PF06189.12 ACL95952.1 - 0.18 10.7 0.0 0.33 9.8 0.0 1.3 1 0 0 1 1 1 0 5'-nucleotidase CoA_trans PF01144.23 ACL95953.1 - 3.9e-76 255.3 0.1 4.4e-76 255.1 0.1 1.0 1 0 0 1 1 1 1 Coenzyme A transferase CoA_trans PF01144.23 ACL95954.1 - 6.3e-43 146.7 0.3 7e-43 146.5 0.3 1.0 1 0 0 1 1 1 1 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 ACL95954.1 - 0.00017 21.6 0.0 0.00024 21.1 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain IF-2B PF01008.17 ACL95954.1 - 0.019 14.2 0.0 0.047 12.9 0.0 1.6 2 0 0 2 2 2 0 Initiation factor 2 subunit family Thiolase_N PF00108.23 ACL95955.1 - 5.9e-72 242.1 0.2 7.5e-72 241.8 0.2 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ACL95955.1 - 2.1e-43 146.9 1.0 4.7e-43 145.7 1.0 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ACL95955.1 - 1.9e-06 27.7 1.9 2.1e-06 27.5 0.5 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Dioxygenase_C PF00775.21 ACL95956.1 - 3.9e-53 179.6 0.0 5e-53 179.2 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase PCDO_beta_N PF12391.8 ACL95956.1 - 3.5e-11 42.5 4.8 3.5e-11 42.5 4.8 1.8 2 0 0 2 2 2 1 Protocatechuate 3,4-dioxygenase beta subunit N terminal CarboxypepD_reg PF13620.6 ACL95956.1 - 3.1e-05 24.2 0.0 8.8e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain Dioxygenase_C PF00775.21 ACL95957.1 - 4.4e-20 71.9 0.0 3e-18 65.9 0.0 2.1 1 1 0 1 1 1 1 Dioxygenase CarboxypepD_reg PF13620.6 ACL95957.1 - 0.0042 17.3 0.1 0.011 16.0 0.1 1.7 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain Lyase_1 PF00206.20 ACL95958.1 - 7.1e-41 140.6 0.1 1e-40 140.1 0.1 1.1 1 0 0 1 1 1 1 Lyase CRS1_YhbY PF01985.21 ACL95958.1 - 0.067 13.4 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 CRS1 / YhbY (CRM) domain Abhydrolase_1 PF00561.20 ACL95959.1 - 2.6e-21 76.4 0.0 2.5e-19 70.0 0.1 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold CMD PF02627.20 ACL95959.1 - 1.2e-17 63.7 1.3 3.5e-17 62.2 0.7 2.1 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Abhydrolase_6 PF12697.7 ACL95959.1 - 2.1e-15 57.9 8.9 2.1e-15 57.9 8.9 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ACL95959.1 - 2.5e-15 56.4 0.2 1.1e-14 54.3 0.1 2.0 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 ACL95959.1 - 4.4e-08 32.2 0.0 6.1e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 Ndr family Esterase PF00756.20 ACL95959.1 - 0.00093 18.9 0.1 0.0015 18.2 0.1 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 ACL95959.1 - 0.0028 17.5 0.2 0.0063 16.4 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 ACL95959.1 - 0.014 15.1 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ACL95959.1 - 0.019 14.5 0.0 0.49 9.8 0.1 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family BAAT_C PF08840.11 ACL95959.1 - 0.02 14.8 0.0 0.058 13.3 0.1 1.6 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal UPF0227 PF05728.12 ACL95959.1 - 0.037 14.0 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_4 PF08386.10 ACL95959.1 - 0.067 13.3 0.1 0.24 11.5 0.0 1.9 2 0 0 2 2 2 0 TAP-like protein DUF2048 PF09752.9 ACL95959.1 - 0.091 11.8 0.2 0.14 11.2 0.2 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 MFS_1 PF07690.16 ACL95960.1 - 1e-48 166.1 71.3 6.7e-48 163.4 47.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ACL95960.1 - 3.4e-19 69.1 25.6 3.2e-18 65.8 7.4 2.3 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 ACL95960.1 - 3e-08 33.4 35.3 5.6e-08 32.5 35.3 1.6 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 ACL95960.1 - 4.1e-08 32.1 1.5 4.1e-08 32.1 1.5 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TMEM43 PF07787.12 ACL95960.1 - 0.06 12.7 2.1 0.11 11.8 2.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 43 BT1 PF03092.16 ACL95960.1 - 0.32 9.2 4.1 0.16 10.2 0.1 2.2 2 0 0 2 2 2 0 BT1 family DUF1501 PF07394.12 ACL95961.1 - 4.6e-74 249.8 0.6 5.3e-74 249.6 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) DUF1800 PF08811.11 ACL95962.1 - 3e-88 296.8 0.6 3.5e-88 296.5 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1800) SLT PF01464.20 ACL95963.1 - 1.1e-26 92.8 0.0 1.5e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase SLT domain SLT_2 PF13406.6 ACL95963.1 - 0.0068 15.7 0.0 0.023 13.9 0.0 1.7 1 1 1 2 2 2 1 Transglycosylase SLT domain Transglycosylas PF06737.14 ACL95963.1 - 0.093 13.4 0.0 0.18 12.5 0.0 1.5 1 0 0 1 1 1 0 Transglycosylase-like domain DMA PF03474.14 ACL95963.1 - 0.14 11.8 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 DMRTA motif TrbC PF04956.13 ACL95964.1 - 1.1e-20 73.6 11.1 1.3e-20 73.5 11.1 1.1 1 0 0 1 1 1 1 TrbC/VIRB2 family YtpI PF14007.6 ACL95964.1 - 0.15 12.3 4.7 0.24 11.6 4.7 1.4 1 1 0 1 1 1 0 YtpI-like protein VirB3 PF05101.13 ACL95965.1 - 6.5e-29 100.0 0.5 7.2e-29 99.9 0.5 1.0 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein CagE_TrbE_VirB PF03135.14 ACL95966.1 - 2.6e-42 145.3 0.0 3.5e-42 144.8 0.0 1.2 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system AAA_10 PF12846.7 ACL95966.1 - 9.3e-05 21.5 0.0 0.0011 17.9 0.0 2.0 2 0 0 2 2 2 1 AAA-like domain AAA_22 PF13401.6 ACL95966.1 - 0.00022 21.5 0.0 0.017 15.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 ACL95966.1 - 0.0015 19.0 0.3 0.015 15.7 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain ABC_tran PF00005.27 ACL95966.1 - 0.17 12.4 0.0 0.44 11.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 ACL95966.1 - 0.18 11.6 0.0 0.49 10.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TrwB_AAD_bind PF10412.9 ACL95966.1 - 0.18 10.7 0.0 0.39 9.6 0.0 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.6 ACL95966.1 - 0.2 11.3 0.0 0.51 10.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain TrbL PF04610.14 ACL95967.1 - 4.5e-34 118.1 20.1 6.3e-34 117.6 20.1 1.2 1 0 0 1 1 1 1 TrbL/VirB6 plasmid conjugal transfer protein CagX PF03524.15 ACL95968.1 - 4.3e-54 183.4 0.0 5e-54 183.2 0.0 1.0 1 0 0 1 1 1 1 Conjugal transfer protein TrbI PF03743.14 ACL95969.1 - 1.7e-57 194.3 2.0 2.2e-57 193.9 2.0 1.2 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein T2SSE PF00437.20 ACL95970.1 - 3.9e-90 301.6 0.1 4.5e-90 301.4 0.1 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_28 PF13521.6 ACL95970.1 - 3.7e-05 24.0 0.0 9.6e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ACL95970.1 - 0.0003 21.2 2.1 0.00046 20.6 0.6 2.0 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 ACL95970.1 - 0.0004 19.7 0.0 0.00075 18.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin ABC_tran PF00005.27 ACL95970.1 - 0.0055 17.2 0.0 0.01 16.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Dynamin_N PF00350.23 ACL95970.1 - 0.015 15.4 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 Dynamin family AAA_29 PF13555.6 ACL95970.1 - 0.019 14.7 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 ACL95970.1 - 0.023 14.3 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 ACL95970.1 - 0.026 14.1 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 ACL95970.1 - 0.031 14.2 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 ACL95970.1 - 0.035 14.2 0.0 0.065 13.3 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase TrwB_AAD_bind PF10412.9 ACL95970.1 - 0.094 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain TsaE PF02367.17 ACL95970.1 - 0.13 12.2 0.1 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FtsK_SpoIIIE PF01580.18 ACL95970.1 - 0.16 11.3 0.5 0.93 8.8 0.0 2.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_14 PF13173.6 ACL95970.1 - 0.16 12.0 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 ACL95970.1 - 0.22 10.6 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.6 ACL95970.1 - 0.22 12.0 0.1 0.33 11.4 0.1 1.2 1 0 0 1 1 1 0 AAA domain Arm-DNA-bind_3 PF13356.6 ACL95971.1 - 0.0049 17.2 0.0 0.0055 17.0 0.0 1.1 1 0 0 1 1 1 1 Arm DNA-binding domain Bac_transf PF02397.16 ACL95972.2 - 4.1e-61 205.8 0.9 4.9e-61 205.5 0.0 1.6 2 0 0 2 2 2 1 Bacterial sugar transferase CoA_binding_3 PF13727.6 ACL95972.2 - 2.2e-16 60.4 0.1 4.4e-16 59.4 0.1 1.5 1 0 0 1 1 1 1 CoA-binding domain PglD_N PF17836.1 ACL95972.2 - 0.00027 21.5 0.0 0.00045 20.8 0.0 1.4 1 0 0 1 1 1 1 PglD N-terminal domain Polysacc_synt_C PF14667.6 ACL95973.1 - 3.8e-15 56.2 13.8 3.8e-15 56.2 13.8 3.4 2 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain Polysacc_synt_3 PF13440.6 ACL95973.1 - 9.4e-13 48.0 0.6 1.6e-12 47.3 0.6 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Polysacc_synt PF01943.17 ACL95973.1 - 1.5e-05 24.5 4.0 1.5e-05 24.5 4.0 2.5 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein Glycos_transf_2 PF00535.26 ACL95974.1 - 5.1e-16 58.9 0.0 6.9e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ACL95974.1 - 2.2e-10 40.8 0.2 3.6e-10 40.1 0.1 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 ACL95974.1 - 4.5e-08 32.9 0.0 0.0048 16.4 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 ACL95974.1 - 1.2e-07 31.3 0.1 6.2e-07 29.0 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Polysacc_deac_1 PF01522.21 ACL95975.1 - 8e-19 67.8 0.0 1.2e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Wzy_C PF04932.15 ACL95976.1 - 4e-12 46.0 8.0 4e-12 46.0 8.0 4.4 3 1 0 3 3 3 1 O-Antigen ligase Wzz PF02706.15 ACL95978.1 - 6.8e-08 32.7 0.0 1.2e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Chain length determinant protein Poly_export PF02563.16 ACL95979.1 - 4.5e-16 58.8 0.0 6.7e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis/export protein SLBB PF10531.9 ACL95979.1 - 1.8e-07 30.9 3.7 3.6e-07 29.9 1.0 2.4 2 0 0 2 2 2 1 SLBB domain ChapFlgA_N PF17656.1 ACL95979.1 - 0.061 13.5 0.0 0.29 11.3 0.0 2.0 1 1 1 2 2 2 0 FlgA N-terminal domain Sel1 PF08238.12 ACL95980.1 - 0.00011 22.7 1.2 0.00024 21.7 0.1 1.9 2 0 0 2 2 2 1 Sel1 repeat GST_N PF02798.20 ACL95981.1 - 2.4e-15 56.6 0.0 4.2e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ACL95981.1 - 2.3e-14 53.6 0.0 3.8e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ACL95981.1 - 2.5e-11 43.7 0.0 4.9e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ACL95981.1 - 2.2e-08 34.0 0.0 3.7e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ACL95981.1 - 4.2e-07 30.1 0.0 6.6e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ACL95981.1 - 6.6e-07 29.5 0.0 1.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RcnB PF11776.8 ACL95982.2 - 1e-21 76.7 7.4 1e-21 76.7 7.4 3.1 3 1 0 3 3 3 1 Nickel/cobalt transporter regulator GatB_N PF02934.15 ACL95983.1 - 2.8e-109 364.7 0.0 3.5e-109 364.4 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 ACL95983.1 - 2.9e-51 173.2 0.1 4.2e-51 172.7 0.1 1.2 1 0 0 1 1 1 1 GatB domain HTH_7 PF02796.15 ACL95983.1 - 0.059 13.5 0.0 0.2 11.7 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Amidase PF01425.21 ACL95984.1 - 1.2e-152 509.0 0.0 1.4e-152 508.8 0.0 1.0 1 0 0 1 1 1 1 Amidase Glu-tRNAGln PF02686.15 ACL95985.1 - 2.2e-18 66.3 0.0 2.8e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit RuvX PF03652.15 ACL95986.1 - 1.2e-36 126.0 0.0 1.4e-36 125.8 0.0 1.0 1 0 0 1 1 1 1 Holliday junction resolvase OTCace_N PF02729.21 ACL95990.1 - 1.6e-38 132.0 0.1 2.2e-38 131.6 0.1 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 ACL95990.1 - 5.2e-24 85.1 0.0 4.6e-23 82.0 0.0 2.2 2 1 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Amidohydro_1 PF01979.20 ACL95991.1 - 2.6e-18 66.5 0.0 6.1e-18 65.2 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ACL95991.1 - 2.8e-14 53.4 0.5 5.3e-12 45.9 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family PUL PF08324.11 ACL95991.1 - 0.16 11.2 0.1 0.25 10.5 0.1 1.3 1 0 0 1 1 1 0 PUL domain G3P_acyltransf PF02660.15 ACL95993.1 - 1.2e-49 168.6 12.0 1.4e-49 168.3 12.0 1.1 1 0 0 1 1 1 1 Glycerol-3-phosphate acyltransferase DNA_processg_A PF02481.15 ACL95994.1 - 1.2e-70 237.1 0.0 1.5e-70 236.7 0.0 1.1 1 0 0 1 1 1 1 DNA recombination-mediator protein A DprA_WH PF17782.1 ACL95994.1 - 2.2e-12 46.9 4.6 4.7e-11 42.6 2.6 2.7 2 0 0 2 2 2 1 DprA winged helix domain Methyltransf_12 PF08242.12 ACL95995.1 - 4.4e-13 49.8 0.1 9e-13 48.8 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ACL95995.1 - 2.8e-12 47.1 0.1 7e-12 45.8 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ACL95995.1 - 1.3e-11 45.0 0.1 3.6e-11 43.6 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ACL95995.1 - 2.9e-11 43.5 0.0 5.5e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ACL95995.1 - 4.4e-09 36.3 0.0 6.5e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 ACL95995.1 - 1.6e-07 31.1 0.0 2.5e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 ACL95995.1 - 0.0029 17.2 0.0 0.0052 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain TPR_2 PF07719.17 ACL95995.1 - 0.0034 17.4 8.4 2.3 8.6 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 ACL95995.1 - 0.005 17.3 9.7 0.024 15.1 0.0 4.1 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 ACL95995.1 - 0.011 15.5 0.1 1.6 8.7 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Methyltransf_16 PF10294.9 ACL95995.1 - 0.2 11.4 0.0 0.47 10.2 0.0 1.5 1 1 0 1 1 1 0 Lysine methyltransferase TPR_14 PF13428.6 ACL95995.1 - 3.7 8.6 27.6 4.3 8.4 0.1 6.8 4 1 3 7 7 7 0 Tetratricopeptide repeat RMI2 PF16100.5 ACL95998.1 - 0.084 12.7 0.1 0.089 12.6 0.1 1.2 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 Topoisom_bac PF01131.20 ACL96000.1 - 3.7e-122 408.3 0.7 4.2e-122 408.1 0.0 1.4 2 0 0 2 2 2 1 DNA topoisomerase Toprim_C_rpt PF13368.6 ACL96000.1 - 4.4e-58 193.1 1.3 7.8e-23 80.2 0.2 4.6 4 0 0 4 4 4 3 Topoisomerase C-terminal repeat Toprim PF01751.22 ACL96000.1 - 5.7e-26 90.7 0.1 1.6e-25 89.3 0.1 1.8 1 0 0 1 1 1 1 Toprim domain zf-C4_Topoisom PF01396.19 ACL96000.1 - 7.9e-16 57.6 2.0 2e-15 56.2 2.0 1.7 1 0 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger Toprim_4 PF13662.6 ACL96000.1 - 0.004 17.6 0.0 0.013 16.0 0.0 1.8 1 0 0 1 1 1 1 Toprim domain IlvN PF07991.12 ACL96000.1 - 0.016 14.8 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain RNB PF00773.19 ACL96002.1 - 1.2e-91 307.5 0.0 1.6e-91 307.0 0.0 1.1 1 0 0 1 1 1 1 RNB domain CSD2 PF17876.1 ACL96002.1 - 4.8e-11 42.7 0.0 3.1e-10 40.1 0.0 2.3 2 0 0 2 2 2 1 Cold shock domain S1 PF00575.23 ACL96002.1 - 1.2e-07 32.0 0.0 5.6e-07 29.8 0.0 2.2 1 0 0 1 1 1 1 S1 RNA binding domain RNase_II_C_S1 PF18614.1 ACL96002.1 - 0.14 12.2 0.0 0.14 12.2 0.0 2.9 4 0 0 4 4 4 0 RNase II-type exonuclease C-terminal S1 domain CE2_N PF17996.1 ACL96003.1 - 6.8e-25 87.2 0.0 1.1e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate esterase 2 N-terminal Lipase_GDSL PF00657.22 ACL96003.1 - 3.5e-12 46.7 0.0 4.8e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ACL96003.1 - 8e-12 45.9 0.3 1.5e-11 45.0 0.3 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Asp_protease_2 PF13650.6 ACL96003.1 - 0.081 13.6 0.1 0.26 12.0 0.0 1.9 2 0 0 2 2 2 0 Aspartyl protease Aminotran_1_2 PF00155.21 ACL96004.1 - 6e-49 167.1 0.0 7.2e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 ACL96004.1 - 0.00066 18.7 0.0 0.0086 15.0 0.0 2.0 2 0 0 2 2 2 1 Allinase Beta_elim_lyase PF01212.21 ACL96004.1 - 0.072 12.4 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_3 PF00202.21 ACL96004.1 - 0.096 11.3 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III Peptidase_M20 PF01546.28 ACL96005.1 - 3.6e-33 115.0 0.5 5.5e-33 114.4 0.5 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ACL96005.1 - 2e-08 34.1 0.0 3.9e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF3782 PF12644.7 ACL96005.1 - 0.0073 16.4 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3782) NUDIX PF00293.28 ACL96006.2 - 3.5e-09 36.8 0.4 9.4e-08 32.2 0.4 2.5 1 1 0 1 1 1 1 NUDIX domain Ribosomal_L33 PF00471.20 ACL96008.1 - 2.5e-15 56.6 0.6 2.8e-15 56.5 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L33 Herpes_pp85 PF04637.12 ACL96008.1 - 0.097 11.1 0.0 0.097 11.1 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF4971 PF16341.5 ACL96008.1 - 0.099 12.5 0.0 0.099 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4971) DUF4229 PF14012.6 ACL96009.1 - 0.042 13.9 4.4 0.064 13.4 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) DUF998 PF06197.13 ACL96009.1 - 0.25 10.9 13.2 0.3 10.7 13.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) Phosphodiest PF01663.22 ACL96010.2 - 2.5e-42 145.7 0.0 3.5e-42 145.3 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 ACL96010.2 - 2.3e-09 37.1 0.1 0.014 14.8 0.0 3.1 3 0 0 3 3 3 3 Sulfatase GGDEF PF00990.21 ACL96011.1 - 3e-51 173.4 0.0 4.8e-51 172.7 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Response_reg PF00072.24 ACL96011.1 - 3e-38 130.4 0.8 3.6e-25 88.3 0.1 2.3 2 0 0 2 2 2 2 Response regulator receiver domain GGDEF_2 PF17853.1 ACL96011.1 - 0.021 15.1 0.3 0.1 12.9 0.0 2.3 2 1 0 2 2 2 0 GGDEF-like domain Response_reg PF00072.24 ACL96012.1 - 1.1e-25 89.9 0.1 1.3e-25 89.7 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain NT5C PF06941.12 ACL96013.1 - 0.00031 20.6 0.0 0.0006 19.7 0.0 1.5 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) ROK PF00480.20 ACL96014.1 - 2.6e-73 247.1 0.0 2.9e-73 246.9 0.0 1.0 1 0 0 1 1 1 1 ROK family BcrAD_BadFG PF01869.20 ACL96014.1 - 0.00088 18.8 0.6 0.37 10.2 0.2 2.2 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family baeRF_family10 PF18854.1 ACL96014.1 - 0.0079 16.4 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 baeRF_family2 PF18844.1 ACL96014.1 - 0.016 15.3 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 2 IMS PF00817.20 ACL96015.1 - 1.7e-47 161.2 0.0 3.1e-47 160.3 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 ACL96015.1 - 1.5e-19 70.9 0.1 2.7e-19 70.0 0.1 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain HHH_5 PF14520.6 ACL96015.1 - 0.00043 20.8 0.2 0.0012 19.4 0.2 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain IMS_HHH PF11798.8 ACL96015.1 - 0.00059 20.0 0.0 0.0016 18.7 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif Cdd1 PF11731.8 ACL96015.1 - 0.027 14.7 0.0 0.39 11.0 0.0 2.3 2 0 0 2 2 2 0 Pathogenicity locus DNA_pol_lambd_f PF10391.9 ACL96015.1 - 0.073 12.9 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda HypA PF01155.19 ACL96015.1 - 0.21 11.6 0.3 0.49 10.4 0.3 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Rubredoxin_2 PF18073.1 ACL96015.1 - 0.26 11.0 2.9 0.43 10.3 2.9 1.3 1 0 0 1 1 1 0 Rubredoxin metal binding domain ClpS PF02617.17 ACL96017.1 - 1.4e-35 120.9 0.2 1.8e-35 120.6 0.2 1.1 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS DUF3842 PF12953.7 ACL96017.1 - 0.12 12.8 0.1 20 5.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3842) AAA_2 PF07724.14 ACL96018.1 - 3.3e-52 177.1 0.0 6.5e-49 166.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 ACL96018.1 - 2.4e-28 98.1 2.0 6.4e-28 96.7 2.0 1.8 1 0 0 1 1 1 1 AAA lid domain AAA PF00004.29 ACL96018.1 - 6.4e-27 94.6 0.0 9.2e-13 48.8 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 ACL96018.1 - 2.2e-25 88.5 0.1 8.3e-25 86.7 0.1 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 ACL96018.1 - 8.4e-18 64.7 0.1 2.7e-11 43.6 0.0 3.0 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ACL96018.1 - 1.9e-12 47.9 2.9 6.7e-06 26.6 0.0 4.2 3 2 0 4 4 3 2 AAA ATPase domain Clp_N PF02861.20 ACL96018.1 - 2e-11 43.9 0.5 1.1e-10 41.5 0.3 2.5 2 0 0 2 2 1 1 Clp amino terminal domain, pathogenicity island component Sigma54_activat PF00158.26 ACL96018.1 - 6.3e-10 39.0 0.1 3.7e-05 23.5 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 ACL96018.1 - 1.1e-09 38.7 0.8 0.0042 17.3 0.2 4.0 2 2 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 ACL96018.1 - 9e-08 31.7 0.3 0.0078 15.6 0.0 3.9 3 1 0 4 4 4 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 ACL96018.1 - 1.5e-07 31.3 2.1 0.07 12.9 0.0 4.2 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 ACL96018.1 - 2.1e-07 31.5 0.0 0.011 16.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain TniB PF05621.11 ACL96018.1 - 9.9e-07 28.3 0.0 0.00048 19.6 0.0 3.4 2 1 0 2 2 2 1 Bacterial TniB protein AAA_3 PF07726.11 ACL96018.1 - 2.5e-06 27.4 0.2 0.0015 18.4 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 ACL96018.1 - 3.3e-06 27.2 0.0 0.1 12.6 0.0 3.1 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 ACL96018.1 - 3.8e-06 27.2 0.1 0.083 13.3 0.1 3.1 2 1 0 2 2 2 2 RNA helicase AAA_7 PF12775.7 ACL96018.1 - 1.4e-05 24.6 0.0 0.25 10.8 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 ACL96018.1 - 1.6e-05 24.7 0.0 0.004 16.9 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.13 ACL96018.1 - 2.1e-05 23.9 0.3 0.0018 17.6 0.0 2.7 2 1 1 3 3 3 1 TIP49 P-loop domain AAA_33 PF13671.6 ACL96018.1 - 2.3e-05 24.6 0.0 0.04 14.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 ACL96018.1 - 2.5e-05 24.2 0.0 0.21 11.6 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_6 PF12774.7 ACL96018.1 - 5e-05 22.4 0.0 0.00014 20.9 0.0 1.7 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_28 PF13521.6 ACL96018.1 - 0.00028 21.2 0.0 0.68 10.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain DNA_pol3_delta2 PF13177.6 ACL96018.1 - 0.00041 20.2 0.0 0.17 11.7 0.0 3.7 4 0 0 4 4 3 1 DNA polymerase III, delta subunit NACHT PF05729.12 ACL96018.1 - 0.00052 20.0 0.1 0.3 11.0 0.0 3.0 2 1 0 2 2 2 1 NACHT domain AAA_17 PF13207.6 ACL96018.1 - 0.001 19.5 0.0 0.39 11.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 ACL96018.1 - 0.0013 18.0 0.0 1.2 8.4 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin Rad17 PF03215.15 ACL96018.1 - 0.0044 17.0 0.0 0.76 9.7 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_25 PF13481.6 ACL96018.1 - 0.0071 15.9 1.1 0.25 10.9 0.1 3.0 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 ACL96018.1 - 0.0085 16.1 0.1 2.4 8.2 0.0 3.5 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 ACL96018.1 - 0.011 15.5 2.9 0.61 9.8 0.1 3.5 3 1 0 3 3 2 0 AAA domain AAA_24 PF13479.6 ACL96018.1 - 0.021 14.6 0.0 4.2 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF2939 PF11159.8 ACL96018.1 - 0.024 15.0 1.2 6.3 7.3 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) RsgA_GTPase PF03193.16 ACL96018.1 - 0.026 14.4 0.0 11 5.9 0.0 2.7 2 0 0 2 2 2 0 RsgA GTPase MCM PF00493.23 ACL96018.1 - 0.026 13.6 0.0 1.2 8.2 0.0 2.4 2 0 0 2 2 2 0 MCM P-loop domain Torsin PF06309.11 ACL96018.1 - 0.027 14.5 0.0 0.095 12.8 0.0 1.9 2 0 0 2 2 1 0 Torsin NTPase_1 PF03266.15 ACL96018.1 - 0.028 14.3 0.1 14 5.5 0.0 3.2 4 0 0 4 4 3 0 NTPase IPT PF01745.16 ACL96018.1 - 0.04 13.3 0.0 0.17 11.3 0.0 2.0 2 0 0 2 2 2 0 Isopentenyl transferase DEAD PF00270.29 ACL96018.1 - 0.05 13.4 1.1 17 5.1 0.0 3.5 3 1 0 4 4 3 0 DEAD/DEAH box helicase SRP54 PF00448.22 ACL96018.1 - 0.081 12.5 0.2 11 5.6 0.1 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain dNK PF01712.19 ACL96018.1 - 0.095 12.5 0.1 1.5 8.7 0.0 2.5 3 0 0 3 3 2 0 Deoxynucleoside kinase Roc PF08477.13 ACL96018.1 - 0.11 12.7 0.0 1.6 9.0 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 ACL96018.1 - 0.14 11.9 0.0 20 5.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF1640 PF07798.11 ACL96019.1 - 3.4e-06 27.2 2.7 0.00031 20.8 2.7 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) DUF4473 PF14747.6 ACL96019.1 - 0.099 13.2 0.1 0.19 12.3 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4473) HIT PF01230.23 ACL96020.1 - 1.9e-26 92.6 0.0 2.4e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 ACL96020.1 - 2.8e-12 47.1 0.0 3.3e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF4287 PF14117.6 ACL96021.1 - 2.2e-11 43.7 0.0 4.2e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4287) 4HBT_3 PF13622.6 ACL96022.1 - 1.4e-39 136.8 0.7 1.6e-39 136.7 0.7 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 ACL96022.1 - 0.037 14.4 0.0 0.082 13.3 0.0 1.6 1 1 0 1 1 1 0 Thioesterase superfamily Amidase PF01425.21 ACL96023.1 - 4.2e-91 306.2 1.5 5.2e-91 305.9 1.5 1.1 1 0 0 1 1 1 1 Amidase Peripla_BP_4 PF13407.6 ACL96023.1 - 0.01 15.4 0.6 0.023 14.3 0.2 1.8 2 0 0 2 2 2 0 Periplasmic binding protein domain DUF4440 PF14534.6 ACL96024.1 - 1.2e-09 38.5 0.1 1.5e-09 38.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 ACL96024.1 - 0.00026 21.2 0.0 0.00038 20.7 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 ACL96024.1 - 0.13 13.0 0.2 0.22 12.2 0.2 1.4 1 1 0 1 1 1 0 SnoaL-like domain UreD PF01774.17 ACL96025.1 - 0.0013 18.7 0.1 0.0021 18.0 0.1 1.3 1 0 0 1 1 1 1 UreD urease accessory protein VCBS PF13517.6 ACL96025.1 - 0.023 15.2 0.3 0.42 11.2 0.1 2.4 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Beta_helix PF13229.6 ACL96026.1 - 0.0036 17.2 0.1 0.024 14.5 0.1 2.0 1 1 0 1 1 1 1 Right handed beta helix region Sel1 PF08238.12 ACL96027.1 - 4e-10 40.0 7.0 2.6e-07 31.1 0.2 4.0 3 0 0 3 3 3 2 Sel1 repeat YqzL PF14006.6 ACL96027.1 - 0.0081 16.5 0.1 0.028 14.8 0.0 1.9 2 0 0 2 2 2 1 YqzL-like protein Acyl-CoA_dh_1 PF00441.24 ACL96028.1 - 2.5e-23 82.9 0.0 2.5e-23 82.9 0.0 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ACL96028.1 - 2.6e-20 72.4 0.0 4.8e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ACL96028.1 - 5.6e-18 65.7 0.6 1e-17 64.8 0.6 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 ACL96029.1 - 8.5e-29 100.7 1.4 1.3e-28 100.1 1.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ACL96029.1 - 1.8e-23 83.4 0.1 4.7e-23 82.0 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ACL96029.1 - 0.0023 18.1 0.0 0.0048 17.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DUF3458_C PF17432.2 ACL96031.1 - 6.3e-109 364.2 0.0 9.7e-109 363.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1 PF01433.20 ACL96031.1 - 2e-51 174.7 0.0 2.7e-51 174.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain DUF3458 PF11940.8 ACL96031.1 - 7.1e-28 96.9 0.0 1.2e-27 96.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold Peptidase_M1_N PF17900.1 ACL96031.1 - 6.5e-12 46.0 0.0 1.1e-11 45.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 ACL96031.1 - 0.00063 20.1 0.1 0.008 16.6 0.1 2.2 1 1 0 1 1 1 1 M61 glycyl aminopeptidase SIP PF04954.13 ACL96031.1 - 0.069 13.7 0.3 0.21 12.1 0.3 1.8 1 0 0 1 1 1 0 Siderophore-interacting protein OTCace_N PF02729.21 ACL96031.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain HATPase_c PF02518.26 ACL96032.1 - 1.8e-25 89.6 0.0 3.7e-25 88.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ACL96032.1 - 1.3e-19 70.0 3.4 2.7e-19 69.0 0.0 3.0 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 ACL96032.1 - 3.5e-19 68.9 0.0 1.6e-14 53.9 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_7 PF12860.7 ACL96032.1 - 4e-14 52.8 0.2 3.8e-12 46.4 0.1 3.3 2 2 1 3 3 3 1 PAS fold PAS_8 PF13188.7 ACL96032.1 - 0.00025 21.0 0.1 0.042 13.9 0.0 2.9 2 0 0 2 2 2 1 PAS domain HATPase_c_3 PF13589.6 ACL96032.1 - 0.0012 18.7 0.0 0.0032 17.3 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 ACL96032.1 - 0.019 15.2 0.0 0.048 14.0 0.0 1.7 1 0 0 1 1 1 0 PAS fold PAS_4 PF08448.10 ACL96032.1 - 0.044 14.0 0.2 0.87 9.9 0.0 3.3 3 1 0 3 3 3 0 PAS fold CENP-F_leu_zip PF10473.9 ACL96032.1 - 0.09 12.8 4.3 0.17 11.9 4.3 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Gas_vesicle_C PF01304.17 ACL96032.1 - 0.14 12.2 1.7 0.36 10.9 1.7 1.6 1 0 0 1 1 1 0 Gas vesicles protein GVPc repeated domain Chorion_S16 PF05836.12 ACL96032.1 - 2.4 8.4 8.1 0.35 11.1 2.9 2.4 2 0 0 2 2 2 0 Chorion protein S16 MeaB PF03308.16 ACL96033.1 - 6.2e-121 402.4 0.7 7.2e-121 402.2 0.7 1.0 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 ACL96033.1 - 5.8e-08 32.5 0.4 4.6e-07 29.6 0.4 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 ACL96033.1 - 0.00036 20.3 0.0 0.00065 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 ACL96033.1 - 0.00091 18.9 0.0 0.0028 17.3 0.0 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 ACL96033.1 - 0.0088 16.0 0.1 0.016 15.1 0.1 1.4 1 0 0 1 1 1 1 NTPase AAA_30 PF13604.6 ACL96033.1 - 0.0094 15.7 1.5 0.011 15.4 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ACL96033.1 - 0.013 15.7 0.0 0.03 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 ACL96033.1 - 0.024 14.7 0.0 0.044 13.8 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain GTP_EFTU PF00009.27 ACL96033.1 - 0.026 14.1 0.0 2.2 7.8 0.0 2.5 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain IstB_IS21 PF01695.17 ACL96033.1 - 0.029 14.1 0.0 0.071 12.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein ATP_bind_1 PF03029.17 ACL96033.1 - 0.043 13.6 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Thymidylate_kin PF02223.17 ACL96033.1 - 0.05 13.3 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase Fer4_NifH PF00142.18 ACL96033.1 - 0.051 13.0 0.0 0.075 12.5 0.0 1.2 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_17 PF13207.6 ACL96033.1 - 0.052 14.0 0.1 0.091 13.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ACL96033.1 - 0.057 14.0 0.6 0.13 12.9 0.2 1.8 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 ACL96033.1 - 0.057 13.2 0.2 0.087 12.5 0.2 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 ACL96033.1 - 0.066 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 KaiC FtsK_SpoIIIE PF01580.18 ACL96033.1 - 0.11 11.9 0.1 0.32 10.3 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 ACL96033.1 - 0.11 11.7 0.3 2.8 7.2 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin MipZ PF09140.11 ACL96033.1 - 0.2 10.9 1.5 0.81 8.9 0.1 2.4 2 1 0 2 2 2 0 ATPase MipZ AAA_16 PF13191.6 ACL96033.1 - 0.26 11.7 2.1 0.29 11.5 0.1 2.0 2 1 0 2 2 2 0 AAA ATPase domain GST_N_3 PF13417.6 ACL96034.1 - 1e-10 41.8 0.0 1.7e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ACL96034.1 - 1.5e-08 34.8 0.0 2.3e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ACL96034.1 - 4e-07 30.3 0.0 6.8e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ACL96034.1 - 0.00027 20.9 0.4 0.00076 19.4 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_4 PF14834.6 ACL96034.1 - 0.00065 20.1 0.0 0.001 19.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Aldolase_II PF00596.21 ACL96034.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Class II Aldolase and Adducin N-terminal domain MFS_1 PF07690.16 ACL96035.1 - 4.6e-40 137.6 44.2 4.6e-40 137.6 44.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 ACL96035.1 - 1.8e-07 29.9 22.2 0.0068 14.7 0.2 4.3 2 2 2 4 4 4 4 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 ACL96035.1 - 0.00023 20.2 20.9 0.01 14.8 20.0 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter UPF0444 PF15475.6 ACL96035.1 - 0.011 16.0 2.1 0.028 14.7 2.1 1.7 1 0 0 1 1 1 0 Transmembrane protein C12orf23, UPF0444 MFS_3 PF05977.13 ACL96035.1 - 1.5 7.1 30.5 15 3.8 30.3 2.2 1 1 0 1 1 1 0 Transmembrane secretion effector MFS_1 PF07690.16 ACL96036.2 - 2.4e-51 174.7 29.6 2.4e-51 174.7 29.6 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 ACL96036.2 - 2.4e-14 52.5 14.1 7.3e-11 41.1 1.8 3.9 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 ACL96036.2 - 5.3e-10 38.7 14.8 9.1e-10 38.0 14.8 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter PTR2 PF00854.21 ACL96036.2 - 0.0041 16.0 4.0 0.0041 16.0 4.0 2.3 2 0 0 2 2 2 1 POT family UL42 PF17638.2 ACL96036.2 - 0.013 15.5 0.1 5.8 6.9 0.0 2.8 3 0 0 3 3 3 0 HCMV UL42 Lyase_1 PF00206.20 ACL96037.1 - 1e-49 169.7 0.0 1.4e-49 169.2 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 ACL96037.1 - 1.5e-27 96.0 0.1 5.7e-27 94.1 0.0 2.1 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus ASL_C PF08328.11 ACL96037.1 - 0.0087 16.1 0.0 0.079 13.1 0.0 2.3 2 1 0 2 2 2 1 Adenylosuccinate lyase C-terminal 2OG-FeII_Oxy_4 PF13661.6 ACL96038.1 - 1.9e-30 105.3 0.0 2.7e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 ACL96038.1 - 3.1e-12 47.2 0.0 5.1e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ofd1_CTDD PF10637.9 ACL96038.1 - 0.0079 15.6 0.0 0.011 15.1 0.0 1.3 1 1 0 1 1 1 1 Oxoglutarate and iron-dependent oxygenase degradation C-term UDG PF03167.19 ACL96039.1 - 1.1e-13 51.5 0.0 1.4e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF1476 PF07345.11 ACL96040.1 - 9.1e-41 138.4 3.8 1e-40 138.2 3.8 1.0 1 0 0 1 1 1 1 ATPase inhibitor subunit zeta SAICAR_synt PF01259.18 ACL96041.1 - 2.5e-63 214.0 0.0 2.9e-63 213.8 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase PurS PF02700.14 ACL96042.1 - 1.6e-32 111.5 0.0 1.8e-32 111.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoribosylformylglycinamidine (FGAM) synthase PI-PLC-C1 PF16670.5 ACL96042.1 - 0.1 11.6 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Phosphoinositide phospholipase C, Ca2+-dependent TetR_N PF00440.23 ACL96043.2 - 1.7e-12 46.9 1.6 3.3e-12 46.0 1.6 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 ACL96043.2 - 4.3e-08 33.4 1.4 4.3e-08 33.4 1.4 2.3 2 1 1 3 3 3 1 BetI-type transcriptional repressor, C-terminal TetR_C_29 PF17938.1 ACL96043.2 - 8.3e-05 22.7 0.4 0.00019 21.5 0.0 1.7 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_11 PF16859.5 ACL96043.2 - 0.00011 22.5 3.2 0.00011 22.5 3.2 2.3 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_24 PF17932.1 ACL96043.2 - 0.00027 21.2 2.1 0.00066 19.9 0.1 2.3 1 1 2 3 3 3 1 Tetracyclin repressor-like, C-terminal domain TetR_C_2 PF08361.11 ACL96043.2 - 0.0015 18.6 0.0 0.0055 16.8 0.0 1.9 1 1 1 2 2 2 1 MAATS-type transcriptional repressor, C-terminal region TetR_C_7 PF14246.6 ACL96043.2 - 0.005 16.8 2.7 0.0068 16.4 1.1 2.0 1 1 0 2 2 2 1 AefR-like transcriptional repressor, C-terminal domain TetR_C_17 PF17922.1 ACL96043.2 - 0.068 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain p450 PF00067.22 ACL96044.1 - 1.9e-31 109.3 0.0 1.1e-18 67.2 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 Glyco_hydro_42 PF02449.15 ACL96044.1 - 0.22 10.8 0.1 0.48 9.7 0.0 1.5 2 0 0 2 2 2 0 Beta-galactosidase Rubredoxin PF00301.20 ACL96045.1 - 2.2e-22 78.8 4.0 2.5e-22 78.6 4.0 1.0 1 0 0 1 1 1 1 Rubredoxin zf-Sec23_Sec24 PF04810.15 ACL96045.1 - 0.0051 16.8 0.6 0.54 10.3 0.0 2.1 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Zn_Tnp_IS1595 PF12760.7 ACL96045.1 - 0.0094 15.9 2.5 2.1 8.4 0.3 2.2 2 0 0 2 2 2 2 Transposase zinc-ribbon domain RbpA PF13397.6 ACL96045.1 - 0.01 16.4 1.5 1.6 9.4 0.2 2.1 1 1 1 2 2 2 0 RNA polymerase-binding protein ADK_lid PF05191.14 ACL96045.1 - 0.02 14.9 0.7 4.9 7.2 0.0 2.1 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-RanBP PF00641.18 ACL96045.1 - 0.023 14.0 3.8 0.78 9.1 0.2 2.2 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others RNA_POL_M_15KD PF02150.16 ACL96045.1 - 0.025 14.5 0.3 0.025 14.5 0.3 1.9 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit UPF0547 PF10571.9 ACL96045.1 - 0.039 14.0 3.4 3.3 7.9 0.3 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zinc_ribbon_10 PF10058.9 ACL96045.1 - 0.055 13.2 0.7 2.7 7.8 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein TF_Zn_Ribbon PF08271.12 ACL96045.1 - 0.067 12.7 1.8 5.4 6.6 0.2 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding HypA PF01155.19 ACL96045.1 - 0.072 13.1 0.0 0.086 12.9 0.0 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RecR PF02132.15 ACL96045.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.4 1 1 0 1 1 1 0 RecR protein Vps36-NZF-N PF16988.5 ACL96045.1 - 0.11 11.9 1.5 0.61 9.5 0.2 2.2 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Rubredoxin_2 PF18073.1 ACL96045.1 - 0.54 10.0 6.5 1.3 8.8 0.6 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain DUF3291 PF11695.8 ACL96046.1 - 1.3e-58 196.6 0.0 1.4e-58 196.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3291) GATase_5 PF13507.6 ACL96048.1 - 1.5e-35 122.6 0.1 3.8e-35 121.3 0.1 1.5 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase_3 PF07685.14 ACL96048.1 - 7.1e-09 35.5 0.0 1.4e-08 34.5 0.0 1.7 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 ACL96048.1 - 1.5e-06 28.1 0.1 2.3e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 ACL96048.1 - 6.5e-05 22.8 0.0 7.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I AIRS_C PF02769.22 ACL96051.1 - 1.2e-53 181.4 10.4 1.6e-34 119.3 1.2 2.2 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.24 ACL96051.1 - 2.3e-47 159.6 6.4 2.6e-23 82.5 0.6 3.0 3 0 0 3 3 3 2 AIR synthase related protein, N-terminal domain FGAR-AT_linker PF18072.1 ACL96051.1 - 3.9e-14 52.9 0.0 8.1e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain HATPase_c PF02518.26 ACL96052.2 - 7.9e-27 94.0 0.1 1.5e-26 93.1 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ACL96052.2 - 4.6e-26 91.2 0.1 8.3e-26 90.4 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ACL96052.2 - 2.7e-19 69.0 0.2 6.8e-19 67.7 0.2 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 ACL96052.2 - 2.6e-09 37.1 0.0 6.7e-09 35.7 0.0 1.7 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 ACL96052.2 - 4.3e-09 36.5 0.0 1.2e-08 35.1 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 ACL96052.2 - 1.6e-08 34.8 0.0 3.7e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 ACL96052.2 - 4.1e-07 30.2 0.0 1e-06 28.9 0.0 1.7 2 0 0 2 2 2 1 PAS domain AsnC_trans_reg PF01037.21 ACL96052.2 - 0.091 12.7 0.0 5.2 7.1 0.0 2.9 3 0 0 3 3 3 0 Lrp/AsnC ligand binding domain FleQ PF06490.11 ACL96052.2 - 0.15 12.4 0.0 1.4 9.3 0.0 2.4 2 0 0 2 2 2 0 Flagellar regulatory protein FleQ Peptidase_M28 PF04389.17 ACL96053.1 - 1.1e-42 146.0 0.0 1.4e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.14 ACL96053.1 - 4.2e-07 29.3 0.1 0.0004 19.5 0.0 2.1 1 1 1 2 2 2 2 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 ACL96053.1 - 2.8e-06 27.2 0.1 4.2e-06 26.6 0.1 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 ACL96053.1 - 0.0061 16.1 0.0 0.0097 15.4 0.0 1.3 1 0 0 1 1 1 1 Nicastrin BolA PF01722.18 ACL96054.1 - 3.9e-15 55.9 0.0 4.1e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein DUF3524 PF12038.8 ACL96054.1 - 0.17 11.7 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3524) Aldo_ket_red PF00248.21 ACL96055.1 - 0.012 14.8 0.0 0.052 12.7 0.0 2.0 1 1 0 1 1 1 0 Aldo/keto reductase family Glutaredoxin PF00462.24 ACL96056.1 - 2.3e-19 69.3 0.1 4.3e-19 68.5 0.1 1.4 2 0 0 2 2 2 1 Glutaredoxin SH3BGR PF04908.15 ACL96056.1 - 0.027 14.6 0.0 0.068 13.3 0.0 1.5 1 1 0 1 1 1 0 SH3-binding, glutamic acid-rich protein Acyl-ACP_TE PF01643.17 ACL96057.1 - 9.9e-16 57.8 0.1 2.6e-08 33.5 0.0 2.0 1 1 1 2 2 2 2 Acyl-ACP thioesterase 4HBT_2 PF13279.6 ACL96057.1 - 2.1e-11 44.4 0.0 2.5e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 ACL96057.1 - 0.0004 20.7 0.0 0.00058 20.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily AHSA1 PF08327.11 ACL96057.1 - 0.028 14.6 0.2 0.17 12.1 0.6 1.9 2 0 0 2 2 2 0 Activator of Hsp90 ATPase homolog 1-like protein Peptidase_M48 PF01435.18 ACL96059.1 - 1.9e-37 129.0 0.4 3.8e-37 128.0 0.4 1.4 1 0 0 1 1 1 1 Peptidase family M48 BSP PF04450.12 ACL96059.1 - 0.0018 18.1 0.0 0.0026 17.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_M56 PF05569.11 ACL96059.1 - 0.0021 17.3 0.1 0.0054 16.0 0.0 1.6 2 0 0 2 2 2 1 BlaR1 peptidase M56 SNARE_assoc PF09335.11 ACL96059.1 - 0.1 13.1 3.2 3.2 8.3 0.3 3.0 3 0 0 3 3 3 0 SNARE associated Golgi protein Peptidase_U49 PF10463.9 ACL96059.1 - 0.29 10.9 0.6 1.4 8.7 0.0 2.1 2 1 0 2 2 2 0 Peptidase U49 DUF4006 PF13179.6 ACL96059.1 - 0.72 9.8 3.4 8.3 6.4 0.6 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF4006) FtsK_4TM PF13491.6 ACL96059.1 - 3.9 7.1 11.5 0.12 12.1 2.8 2.1 2 0 0 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE zf-TFIIB PF13453.6 ACL96060.1 - 1.5e-19 69.0 0.6 2.2e-19 68.5 0.6 1.3 1 0 0 1 1 1 1 Transcription factor zinc-finger TF_Zn_Ribbon PF08271.12 ACL96060.1 - 0.0045 16.5 0.4 0.0075 15.8 0.4 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding DZR PF12773.7 ACL96060.1 - 0.069 13.2 0.4 0.12 12.4 0.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon SelP_N PF04592.14 ACL96060.1 - 0.13 11.6 3.5 0.15 11.4 3.5 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zn-ribbon_8 PF09723.10 ACL96060.1 - 0.27 11.4 3.1 0.44 10.7 2.4 1.9 1 1 1 2 2 2 0 Zinc ribbon domain zinc_ribbon_9 PF14369.6 ACL96060.1 - 1.3 9.4 4.8 38 4.7 5.3 2.3 1 1 1 2 2 2 0 zinc-ribbon Ribosomal_S4 PF00163.19 ACL96061.1 - 3e-25 89.0 3.1 5.2e-25 88.2 3.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 ACL96061.1 - 1.9e-19 69.1 0.0 3.1e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 ACL96061.1 - 0.0044 16.8 0.8 0.0059 16.4 0.0 1.5 2 0 0 2 2 2 1 S4 domain Ub-Mut7C PF14451.6 ACL96061.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Mut7-C ubiquitin ParE_toxin PF05016.15 ACL96063.3 - 1.8e-18 66.9 0.9 2.2e-18 66.7 0.9 1.1 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE Esterase PF00756.20 ACL96065.1 - 2.1e-56 191.4 0.0 2.4e-56 191.2 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 ACL96065.1 - 1.6e-06 27.2 0.1 3.7e-06 26.1 0.1 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 ACL96065.1 - 2.6e-05 23.4 0.1 0.00021 20.4 0.1 2.0 1 1 0 1 1 1 1 Chlorophyllase Peptidase_S9 PF00326.21 ACL96065.1 - 0.00012 21.7 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 ACL96065.1 - 0.00017 21.0 0.2 0.00038 19.8 0.2 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ACL96065.1 - 0.0002 22.1 2.6 0.00027 21.6 2.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 ACL96065.1 - 0.00039 20.0 0.0 0.0042 16.6 0.0 2.0 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_1 PF00561.20 ACL96065.1 - 0.0014 18.3 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold ADH_N PF08240.12 ACL96066.1 - 1.3e-24 86.2 1.2 2.2e-24 85.4 1.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ACL96066.1 - 1.4e-20 73.6 0.1 2.5e-20 72.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ACL96066.1 - 1.6e-06 29.2 0.0 3.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ACL96066.1 - 0.0057 16.2 0.4 0.04 13.4 0.4 2.2 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus TrkA_N PF02254.18 ACL96066.1 - 0.022 15.0 0.1 0.043 14.1 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain LysR_substrate PF03466.20 ACL96067.1 - 5.5e-48 163.1 3.7 5.5e-48 163.1 3.7 1.5 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 ACL96067.1 - 1e-19 70.2 1.8 2.4e-19 69.0 1.8 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_IclR PF09339.10 ACL96067.1 - 0.00068 19.4 1.1 0.0063 16.3 0.4 2.7 2 0 0 2 2 2 1 IclR helix-turn-helix domain MarR_2 PF12802.7 ACL96067.1 - 0.012 15.4 0.2 0.012 15.4 0.2 2.4 3 0 0 3 3 3 0 MarR family HTH_24 PF13412.6 ACL96067.1 - 0.024 14.2 0.1 0.064 12.8 0.1 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding VirD1 PF07328.11 ACL96067.1 - 0.027 14.4 0.1 0.058 13.4 0.1 1.5 1 0 0 1 1 1 0 T-DNA border endonuclease VirD1 DUF1254 PF06863.12 ACL96068.1 - 1.7e-38 131.7 0.1 3.4e-38 130.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1254) DUF1214 PF06742.11 ACL96068.1 - 2e-29 102.2 0.1 3.5e-28 98.2 0.0 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF1214) Host_attach PF10116.9 ACL96069.1 - 1.2e-19 71.3 1.7 2.1e-18 67.2 1.7 2.0 1 1 0 1 1 1 1 Protein required for attachment to host cells baeRF_family12 PF18856.1 ACL96069.1 - 1.8e-16 61.0 0.2 8.2e-16 58.8 0.2 1.8 1 1 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 12 baeRF_family10 PF18854.1 ACL96069.1 - 2.3e-07 31.2 1.2 3.1e-07 30.7 1.2 1.2 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 baeRF_family3 PF18845.1 ACL96069.1 - 0.00014 22.2 0.1 0.00016 21.9 0.1 1.1 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 3 baeRF_family2 PF18844.1 ACL96069.1 - 0.0013 18.8 3.5 0.0016 18.5 3.5 1.2 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 2 SpoU_methylase PF00588.19 ACL96070.1 - 2.2e-30 105.7 0.0 2.8e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family HATPase_c PF02518.26 ACL96071.1 - 4.5e-26 91.6 0.0 8.9e-26 90.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ACL96071.1 - 7.2e-24 84.1 0.1 1.4e-23 83.2 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ACL96071.1 - 4.1e-12 45.9 0.1 4.1e-12 45.9 0.1 3.4 5 0 0 5 5 5 1 His Kinase A (phospho-acceptor) domain PGM_PMM_II PF02879.16 ACL96071.1 - 0.00092 19.8 1.6 0.011 16.4 0.1 3.2 4 0 0 4 4 4 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II HATPase_c_2 PF13581.6 ACL96071.1 - 0.012 15.6 0.0 0.036 14.0 0.0 1.8 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain SBP_bac_3 PF00497.20 ACL96071.1 - 0.017 14.6 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 FleQ PF06490.11 ACL96071.1 - 0.027 14.8 0.0 0.064 13.6 0.0 1.7 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ HATPase_c_3 PF13589.6 ACL96071.1 - 0.12 12.2 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 ACL96071.1 - 0.28 11.6 3.0 0.44 11.0 0.1 3.0 3 0 0 3 3 3 0 HAMP domain Iso_dh PF00180.20 ACL96072.1 - 2.6e-75 253.7 0.0 3e-75 253.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF2939 PF11159.8 ACL96073.1 - 9.8e-22 77.2 0.3 2.5e-21 75.9 0.6 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2939) TRP PF06011.12 ACL96073.1 - 0.036 12.8 1.2 0.046 12.5 1.2 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Mem_trans PF03547.18 ACL96074.1 - 6.3e-17 61.0 14.6 7.1e-13 47.7 9.3 2.0 2 0 0 2 2 2 2 Membrane transport protein MatE PF01554.18 ACL96074.1 - 3 7.5 17.3 0.57 9.8 1.4 3.3 2 1 1 3 3 3 0 MatE Glyoxalase PF00903.25 ACL96075.1 - 1.1e-07 32.1 0.0 1.6e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ACL96075.1 - 9.7e-07 29.6 0.0 1.1e-06 29.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain GyrI-like PF06445.15 ACL96076.1 - 9.6e-34 116.9 0.0 1.4e-33 116.4 0.0 1.2 1 0 0 1 1 1 1 GyrI-like small molecule binding domain HTH_18 PF12833.7 ACL96076.1 - 2.3e-17 63.0 2.0 2.3e-17 63.0 2.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 ACL96076.1 - 2.4e-12 46.6 0.0 8.3e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family Cass2 PF14526.6 ACL96076.1 - 1.2e-11 44.9 0.0 1.9e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Integron-associated effector binding protein tRNA-synt_2c PF01411.19 ACL96077.1 - 5.8e-217 721.6 0.0 7.9e-217 721.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) DHHA1 PF02272.19 ACL96077.1 - 4.6e-19 69.2 9.5 1.1e-18 68.0 9.5 1.7 1 0 0 1 1 1 1 DHHA1 domain tRNA_SAD PF07973.14 ACL96077.1 - 4.9e-17 61.7 0.0 1.7e-16 60.0 0.0 2.0 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Rieske PF00355.26 ACL96078.1 - 1.5e-09 37.7 0.0 1.8e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain FAA_hydrolase PF01557.18 ACL96079.1 - 6.1e-35 120.9 0.0 7.6e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydro_N_2 PF18288.1 ACL96079.1 - 4e-23 81.6 0.0 6.7e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal domain 2 HgmA PF04209.13 ACL96080.1 - 4.4e-218 724.1 0.1 5e-218 724.0 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Glyoxalase_5 PF14696.6 ACL96081.1 - 7.4e-45 152.5 0.0 2.4e-44 150.9 0.0 1.7 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase PF00903.25 ACL96081.1 - 1.5e-15 57.5 0.3 5.8e-14 52.4 0.1 2.2 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ACL96081.1 - 3.9e-12 46.4 0.1 3e-06 27.5 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 ACL96081.1 - 4.8e-06 26.8 0.8 0.044 13.9 0.1 2.8 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_6 PF18029.1 ACL96081.1 - 0.0077 17.0 0.1 3 8.7 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase-like domain DUF1338 PF07063.13 ACL96081.1 - 0.086 12.0 0.0 0.2 10.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1338) Aminotran_1_2 PF00155.21 ACL96082.1 - 6e-51 173.7 0.0 7.4e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II SH3_4 PF06347.13 ACL96082.1 - 0.012 15.4 0.0 0.031 14.1 0.0 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain AsnC_trans_reg PF01037.21 ACL96083.1 - 2e-24 85.3 0.1 2.9e-24 84.8 0.1 1.2 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 ACL96083.1 - 2e-20 72.1 0.3 3.2e-20 71.4 0.3 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 ACL96083.1 - 1.3e-17 63.3 0.3 2.3e-17 62.5 0.3 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain MarR PF01047.22 ACL96083.1 - 1.5e-06 28.1 0.0 2.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.7 ACL96083.1 - 1.9e-05 24.4 0.2 3.6e-05 23.6 0.2 1.5 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 ACL96083.1 - 0.00011 22.2 0.0 0.00029 20.8 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 ACL96083.1 - 0.00064 19.7 0.1 0.0012 18.8 0.1 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_11 PF08279.12 ACL96083.1 - 0.0014 18.5 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 HTH domain HTH_47 PF16221.5 ACL96083.1 - 0.0024 17.4 0.0 0.0062 16.1 0.0 1.7 2 0 0 2 2 2 1 winged helix-turn-helix Fe_dep_repress PF01325.19 ACL96083.1 - 0.0074 16.5 0.0 0.019 15.2 0.0 1.6 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain HTH_IclR PF09339.10 ACL96083.1 - 0.018 14.8 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_5 PF01022.20 ACL96083.1 - 0.02 14.7 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family PheRS_DBD1 PF18552.1 ACL96083.1 - 0.021 14.6 0.0 0.057 13.2 0.0 1.7 1 0 0 1 1 1 0 PheRS DNA binding domain 1 Rrf2 PF02082.20 ACL96083.1 - 0.062 13.7 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator HTH_DeoR PF08220.12 ACL96083.1 - 0.065 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_28 PF13518.6 ACL96083.1 - 0.079 13.1 0.1 0.16 12.1 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain LexA_DNA_bind PF01726.16 ACL96083.1 - 0.088 12.6 0.2 0.76 9.6 0.2 2.3 1 1 0 1 1 1 0 LexA DNA binding domain Band_7 PF01145.25 ACL96084.1 - 2.2e-22 79.9 0.4 3.1e-22 79.4 0.4 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family YbaB_DNA_bd PF02575.16 ACL96084.1 - 0.0056 16.9 3.0 0.01 16.0 3.0 1.4 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family DUF1905 PF08922.11 ACL96085.1 - 3.3e-24 84.8 0.0 3.7e-24 84.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1905) CPBP PF02517.16 ACL96086.1 - 2.3e-14 53.5 8.3 2.3e-14 53.5 8.3 2.6 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease Peptidase_M61_N PF17899.1 ACL96087.1 - 6e-45 153.3 0.1 1.1e-44 152.5 0.1 1.4 1 0 0 1 1 1 1 Peptidase M61 N-terminal domain Peptidase_M61 PF05299.12 ACL96087.1 - 2.6e-31 108.5 0.0 4.9e-31 107.6 0.0 1.5 1 0 0 1 1 1 1 M61 glycyl aminopeptidase PDZ_2 PF13180.6 ACL96087.1 - 1.2e-05 25.6 0.0 2.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 ACL96087.1 - 0.0038 17.0 0.0 0.011 15.5 0.0 1.8 2 0 0 2 2 2 1 PDZ domain TGT_C1 PF14809.6 ACL96087.1 - 0.18 12.2 0.4 1.1 9.6 0.0 2.2 2 0 0 2 2 2 0 C1 domain of tRNA-guanine transglycosylase dimerisation Tubulin PF00091.25 ACL96088.1 - 3.5e-42 144.9 0.3 5.2e-42 144.3 0.3 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 ACL96088.1 - 2.6e-38 130.2 3.1 6e-38 129.0 3.1 1.7 1 0 0 1 1 1 1 FtsZ family, C-terminal domain Tubulin_2 PF13809.6 ACL96088.1 - 8 5.5 6.3 7.6 5.6 1.6 2.2 1 1 1 2 2 2 0 Tubulin like FtsA PF14450.6 ACL96089.1 - 4.7e-32 110.5 0.5 8.2e-22 77.6 0.0 2.1 2 0 0 2 2 2 2 Cell division protein FtsA SHS2_FTSA PF02491.20 ACL96089.1 - 7.3e-16 58.3 0.0 4e-15 56.0 0.0 2.1 2 0 0 2 2 2 1 SHS2 domain inserted in FTSA MreB_Mbl PF06723.13 ACL96089.1 - 6.9e-09 35.0 3.9 2.6e-08 33.1 0.9 2.5 2 1 0 2 2 2 1 MreB/Mbl protein EutA PF06277.11 ACL96089.1 - 9.6e-05 21.4 0.4 9.6e-05 21.4 0.4 1.5 2 0 0 2 2 2 1 Ethanolamine utilisation protein EutA PilM_2 PF11104.8 ACL96089.1 - 0.00023 20.3 0.0 0.0075 15.3 0.0 2.7 3 0 0 3 3 3 1 Type IV pilus assembly protein PilM; Hydantoinase_A PF01968.18 ACL96089.1 - 0.00035 19.9 3.4 0.02 14.1 0.2 3.1 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase Ppx-GppA PF02541.16 ACL96089.1 - 0.011 15.2 0.3 0.018 14.5 0.3 1.3 1 0 0 1 1 1 0 Ppx/GppA phosphatase family DDR PF08841.10 ACL96089.1 - 0.12 11.4 6.3 0.025 13.6 0.6 2.4 3 0 0 3 3 3 0 Diol dehydratase reactivase ATPase-like domain Dodecin PF07311.12 ACL96089.1 - 0.12 12.6 0.4 0.28 11.5 0.4 1.5 1 0 0 1 1 1 0 Dodecin POTRA_1 PF08478.10 ACL96090.1 - 4.4e-18 65.3 0.0 1.6e-17 63.5 0.0 1.9 2 1 0 2 2 2 1 POTRA domain, FtsQ-type FtsQ PF03799.15 ACL96090.1 - 2.4e-14 54.2 0.9 3.9e-14 53.5 0.9 1.4 1 0 0 1 1 1 1 Cell division protein FtsQ Dala_Dala_lig_C PF07478.13 ACL96091.1 - 1.1e-38 132.9 0.0 1.4e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Dala_Dala_lig_N PF01820.21 ACL96091.1 - 2.6e-17 63.2 0.1 1.6e-15 57.4 0.1 2.2 1 1 0 1 1 1 1 D-ala D-ala ligase N-terminus ATP-grasp_3 PF02655.14 ACL96091.1 - 4.5e-07 30.1 0.0 6.3e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 ACL96091.1 - 2e-05 24.2 0.0 0.00039 20.1 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 ACL96091.1 - 0.00059 19.6 0.0 0.36 10.6 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATPgrasp_ST PF14397.6 ACL96091.1 - 0.19 10.9 0.0 4.1 6.6 0.0 2.1 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Peptidase_M28 PF04389.17 ACL96092.1 - 7e-21 74.8 0.1 1.3e-20 73.9 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 ACL96092.1 - 5.5e-08 32.8 0.1 1.8e-07 31.1 0.1 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 PA PF02225.22 ACL96092.1 - 0.0013 18.7 2.8 0.0013 18.7 2.8 2.6 2 1 0 2 2 2 1 PA domain DUF4910 PF16254.5 ACL96092.1 - 0.003 16.5 0.0 0.005 15.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4910) MurB_C PF02873.16 ACL96093.1 - 3.1e-25 88.5 0.0 6.9e-25 87.4 0.0 1.6 2 0 0 2 2 2 1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain FAD_binding_4 PF01565.23 ACL96093.1 - 8.9e-20 70.8 2.1 1.4e-19 70.2 2.1 1.2 1 0 0 1 1 1 1 FAD binding domain Mur_ligase PF01225.25 ACL96094.1 - 1.5e-27 95.7 0.3 3.7e-27 94.5 0.3 1.7 1 0 0 1 1 1 1 Mur ligase family, catalytic domain Mur_ligase_M PF08245.12 ACL96094.1 - 2.7e-27 96.0 0.0 3.7e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 ACL96094.1 - 2.8e-21 75.6 0.0 1.1e-19 70.4 0.0 3.1 3 0 0 3 3 3 1 Mur ligase family, glutamate ligase domain AAA_15 PF13175.6 ACL96096.1 - 0.0001 22.2 0.0 0.00012 21.9 0.0 1.0 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 ACL96096.1 - 0.012 15.0 0.0 0.013 15.0 0.0 1.0 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain SOUL PF04832.12 ACL96097.1 - 9.1e-49 165.9 0.0 1.5e-29 103.3 0.1 2.1 1 1 1 2 2 2 2 SOUL heme-binding protein DUF2076 PF09849.9 ACL96097.1 - 0.028 14.5 0.0 0.035 14.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Agglutinin_C PF18021.1 ACL96097.1 - 0.11 13.1 0.0 0.15 12.6 0.0 1.3 1 0 0 1 1 1 0 Agglutinin C-terminal Glyco_hydro_127 PF07944.12 ACL96098.1 - 1.2e-163 545.3 0.0 1.6e-163 545.0 0.0 1.1 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 TAT_signal PF10518.9 ACL96098.1 - 0.22 11.5 3.1 1 9.3 3.1 2.3 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence TPR_4 PF07721.14 ACL96098.1 - 0.23 12.2 6.3 0.69 10.7 0.3 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_tran_28_C PF04101.16 ACL96099.1 - 9e-37 126.6 0.0 1.3e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_28 PF03033.20 ACL96099.1 - 6.1e-29 100.8 0.0 1.2e-28 99.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_trans_4_4 PF13579.6 ACL96099.1 - 7.4e-06 26.5 3.3 1.6e-05 25.4 3.3 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 ACL96099.1 - 7.8e-05 22.7 0.1 0.00013 22.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_3 PF13528.6 ACL96099.1 - 0.0011 18.3 0.0 0.0041 16.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 1 HisKA_3 PF07730.13 ACL96099.1 - 2.4 8.8 4.7 1.5 9.4 0.5 2.5 2 0 0 2 2 2 0 Histidine kinase Rnk_N PF14760.6 ACL96099.1 - 9.3 6.8 11.0 1.1 9.8 1.1 3.2 3 0 0 3 3 3 0 Rnk N-terminus FTSW_RODA_SPOVE PF01098.19 ACL96100.1 - 2.3e-75 253.9 18.2 3e-75 253.5 18.2 1.0 1 0 0 1 1 1 1 Cell cycle protein Cad PF03596.13 ACL96100.1 - 0.054 13.4 1.1 0.16 11.8 0.1 2.3 2 0 0 2 2 2 0 Cadmium resistance transporter HEAT_2 PF13646.6 ACL96101.1 - 0.0058 17.0 6.1 0.024 15.0 2.9 2.2 1 1 1 2 2 2 2 HEAT repeats Hen1_L PF12623.7 ACL96101.1 - 0.062 12.3 0.0 0.077 12.0 0.0 1.1 1 0 0 1 1 1 0 RNA repair, ligase-Pnkp-associating, region of Hen1 Trp_halogenase PF04820.14 ACL96101.1 - 0.12 11.2 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase HWE_HK PF07536.14 ACL96102.1 - 1.5e-26 92.9 0.1 2.6e-26 92.1 0.1 1.4 1 0 0 1 1 1 1 HWE histidine kinase PAS_4 PF08448.10 ACL96102.1 - 5.6e-22 78.1 0.1 1.4e-21 76.8 0.1 1.7 1 0 0 1 1 1 1 PAS fold HisKA_2 PF07568.12 ACL96102.1 - 5.8e-07 29.5 0.2 1.1e-06 28.7 0.2 1.4 1 0 0 1 1 1 1 Histidine kinase HATPase_c_2 PF13581.6 ACL96102.1 - 0.00024 21.1 0.0 0.014 15.4 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain PAS_9 PF13426.7 ACL96102.1 - 0.00026 21.2 0.0 0.00053 20.2 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 ACL96102.1 - 0.09 12.8 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 PAS fold Voltage_CLC PF00654.20 ACL96103.1 - 2.1e-56 191.7 43.9 2.1e-56 191.7 43.9 2.1 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 ACL96103.1 - 1.5e-08 35.0 0.0 0.0012 19.2 0.0 2.5 2 0 0 2 2 2 2 CBS domain Mur_ligase_M PF08245.12 ACL96104.1 - 3.3e-32 112.1 0.0 4.6e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain 2-Hacid_dh_C PF02826.19 ACL96104.1 - 1.2e-05 24.7 0.0 2.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Mur_ligase_C PF02875.21 ACL96104.1 - 2e-05 24.7 0.0 7.5e-05 22.9 0.0 2.0 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain IlvN PF07991.12 ACL96104.1 - 0.0006 19.4 0.1 0.0031 17.1 0.0 2.2 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 ACL96104.1 - 0.0013 19.0 0.0 0.0053 17.0 0.0 2.1 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_2 PF03446.15 ACL96104.1 - 0.0029 17.8 0.6 0.0065 16.6 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.6 ACL96104.1 - 0.011 16.2 0.0 0.027 14.9 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 ACL96104.1 - 0.016 14.5 0.1 0.028 13.7 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.21 ACL96104.1 - 0.017 15.2 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Glycos_transf_4 PF00953.21 ACL96105.1 - 9.2e-34 116.7 16.8 9.2e-34 116.7 16.8 2.5 3 0 0 3 3 3 1 Glycosyl transferase family 4 MraY_sig1 PF10555.9 ACL96105.1 - 0.00056 19.3 3.1 0.0017 17.8 3.1 1.9 1 0 0 1 1 1 1 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 DUF1673 PF07895.11 ACL96105.1 - 0.063 13.0 2.7 1.9 8.1 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) Mur_ligase_M PF08245.12 ACL96106.1 - 1e-40 139.8 0.0 1.4e-40 139.4 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 ACL96106.1 - 7e-11 42.2 0.2 1.5e-09 37.9 0.0 2.4 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Mur_ligase PF01225.25 ACL96106.1 - 1.9e-07 31.3 0.0 9.5e-07 29.1 0.0 2.3 1 0 0 1 1 1 1 Mur ligase family, catalytic domain ATP-synt_DE_N PF02823.16 ACL96106.1 - 0.042 13.7 0.1 0.92 9.5 0.0 2.7 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Mur_ligase_M PF08245.12 ACL96107.1 - 4e-42 144.4 0.0 5.7e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 ACL96107.1 - 4.1e-21 75.0 0.1 1.4e-19 70.1 0.0 2.9 3 0 0 3 3 3 1 Mur ligase family, glutamate ligase domain Mur_ligase PF01225.25 ACL96107.1 - 1.4e-12 47.8 0.7 5.4e-12 45.9 0.1 2.4 2 0 0 2 2 2 1 Mur ligase family, catalytic domain Transpeptidase PF00905.22 ACL96108.1 - 3.2e-52 177.6 0.0 4e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 Penicillin binding protein transpeptidase domain PBP_dimer PF03717.15 ACL96108.1 - 4.7e-10 40.1 0.0 2.9e-09 37.5 0.0 2.0 1 1 0 1 1 1 1 Penicillin-binding Protein dimerisation domain Beta-lactamase2 PF13354.6 ACL96108.1 - 8.5e-05 22.2 0.1 0.00046 19.8 0.1 2.2 2 1 0 2 2 2 1 Beta-lactamase enzyme family PEN-2 PF10251.9 ACL96108.1 - 0.14 12.6 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase DivIC PF04977.15 ACL96109.1 - 1.3e-05 24.8 0.9 2e-05 24.3 0.9 1.3 1 0 0 1 1 1 1 Septum formation initiator TMIE PF16038.5 ACL96109.1 - 0.005 16.7 0.1 0.0077 16.1 0.1 1.3 1 0 0 1 1 1 1 TMIE protein DUF2730 PF10805.8 ACL96109.1 - 0.069 13.3 0.1 0.08 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) PepSY_TM PF03929.16 ACL96109.1 - 0.073 12.7 0.3 0.073 12.7 0.3 1.6 1 1 1 2 2 2 0 PepSY-associated TM region LapA_dom PF06305.11 ACL96109.1 - 0.11 12.4 0.2 0.2 11.5 0.2 1.5 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Methyltransf_5 PF01795.19 ACL96110.1 - 4.5e-93 312.1 0.0 5.1e-93 312.0 0.0 1.0 1 0 0 1 1 1 1 MraW methylase family Methyltransf_11 PF08241.12 ACL96110.1 - 2.4e-05 24.9 0.1 0.25 12.0 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_24 PF13578.6 ACL96110.1 - 0.014 16.4 0.0 0.12 13.4 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 ACL96110.1 - 0.016 15.9 0.1 1.8 9.3 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain ADH_zinc_N PF00107.26 ACL96110.1 - 0.031 14.2 0.0 10 6.1 0.0 2.4 2 1 0 2 2 2 0 Zinc-binding dehydrogenase Ubie_methyltran PF01209.18 ACL96110.1 - 0.053 12.8 0.0 0.12 11.7 0.0 1.5 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family ACP_syn_III_C PF08541.10 ACL96110.1 - 0.11 12.7 0.0 0.72 10.1 0.0 2.2 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Methyltransf_31 PF13847.6 ACL96110.1 - 0.12 12.1 0.0 1.4 8.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain MraZ PF02381.18 ACL96111.1 - 4.7e-19 68.2 0.0 2.2e-09 37.2 0.0 2.1 2 0 0 2 2 2 2 MraZ protein, putative antitoxin-like LysR_substrate PF03466.20 ACL96112.1 - 7.8e-35 120.1 4.5 7.8e-35 120.1 4.5 1.5 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 ACL96112.1 - 1.6e-17 63.2 1.3 3.5e-17 62.1 1.3 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Abhydrolase_6 PF12697.7 ACL96113.1 - 8.2e-08 33.1 11.9 8.2e-08 33.1 11.9 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ACL96113.1 - 9e-06 25.5 0.1 0.00015 21.5 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold FMN_bind_2 PF04299.12 ACL96114.1 - 2e-30 105.7 0.0 2.3e-30 105.5 0.0 1.0 1 0 0 1 1 1 1 Putative FMN-binding domain Amidase_2 PF01510.25 ACL96115.1 - 7.1e-30 104.1 0.0 1e-29 103.6 0.0 1.2 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase PG_binding_1 PF01471.18 ACL96115.1 - 3.1e-08 33.7 0.0 4.9e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Putative peptidoglycan binding domain EamA PF00892.20 ACL96116.1 - 3.8e-25 88.7 40.4 1.6e-15 57.5 16.7 2.1 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 ACL96116.1 - 0.0035 16.4 0.3 0.0035 16.4 0.3 2.2 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like PUNUT PF16913.5 ACL96116.1 - 0.016 14.5 0.4 0.016 14.5 0.4 2.4 2 0 0 2 2 2 0 Purine nucleobase transmembrane transport Mg_trans_NIPA PF05653.14 ACL96116.1 - 0.038 13.1 9.4 0.1 11.7 0.5 2.2 2 0 0 2 2 2 0 Magnesium transporter NIPA FMO-like PF00743.19 ACL96117.1 - 3.3e-22 78.6 0.2 2.2e-21 75.9 0.0 2.1 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ACL96117.1 - 1.1e-12 47.9 0.1 4e-12 46.0 0.0 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ACL96117.1 - 7.5e-11 41.8 0.0 1.4e-08 34.3 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ACL96117.1 - 1.8e-09 37.7 0.1 2.4e-07 30.9 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 ACL96117.1 - 1.1e-07 31.4 0.3 4.4e-05 22.8 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 ACL96117.1 - 1.3e-07 31.5 1.1 6.4e-05 22.7 0.0 3.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 ACL96117.1 - 2.2e-07 30.4 0.3 1.1e-05 24.9 0.1 2.5 3 0 0 3 3 3 1 Thi4 family Pyr_redox PF00070.27 ACL96117.1 - 5.9e-06 26.8 0.2 0.0025 18.3 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ACL96117.1 - 0.00069 18.8 1.6 0.0056 15.8 0.1 2.7 3 0 0 3 3 3 1 FAD binding domain Shikimate_DH PF01488.20 ACL96117.1 - 0.00091 19.3 0.1 0.26 11.3 0.0 3.0 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 ACL96117.1 - 0.0015 17.7 0.8 8.2 5.3 0.0 3.2 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_7 PF13241.6 ACL96117.1 - 0.003 18.0 0.2 0.012 16.0 0.0 2.1 2 1 0 2 2 2 1 Putative NAD(P)-binding FAD_oxidored PF12831.7 ACL96117.1 - 0.011 15.1 0.6 0.042 13.2 0.2 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ACL96117.1 - 0.06 13.3 2.8 3 7.8 0.1 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 ACL96117.1 - 0.077 12.2 1.4 0.4 9.9 0.1 2.5 3 0 0 3 3 3 0 FAD binding domain MCRA PF06100.11 ACL96117.1 - 0.094 11.5 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 MCRA family Trp_halogenase PF04820.14 ACL96117.1 - 0.11 11.3 0.9 9.9 4.9 0.1 2.4 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.22 ACL96117.1 - 0.52 9.3 6.1 1.8 7.5 0.2 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A DUF2236 PF09995.9 ACL96118.1 - 3.9e-42 145.0 9.3 3.9e-42 145.0 9.3 1.3 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) LHC PF00556.20 ACL96119.1 - 5.9 7.2 9.4 1.2 9.4 3.7 2.6 3 0 0 3 3 3 0 Antenna complex alpha/beta subunit DUF4440 PF14534.6 ACL96120.1 - 7.8e-11 42.3 0.5 1.3e-10 41.7 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 ACL96120.1 - 3.6e-08 33.7 0.1 5e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 ACL96120.1 - 1.1e-07 32.5 0.8 2.5e-07 31.3 0.8 1.7 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 ACL96120.1 - 2.2e-07 31.0 0.6 3e-07 30.6 0.6 1.2 1 0 0 1 1 1 1 SnoaL-like domain Lumazine_bd_2 PF12893.7 ACL96120.1 - 0.0029 18.3 0.0 0.0061 17.2 0.0 1.7 1 1 0 1 1 1 1 Putative lumazine-binding DUF1348 PF07080.11 ACL96120.1 - 0.028 14.4 0.0 0.059 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1348) DUF2798 PF11391.8 ACL96120.1 - 0.054 13.5 0.4 0.097 12.7 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2798) HTH_18 PF12833.7 ACL96121.1 - 7.8e-17 61.3 1.7 2.2e-16 59.9 1.7 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 ACL96121.1 - 5.2e-09 36.0 0.0 0.0039 17.2 0.0 2.5 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family DUF3052 PF11253.8 ACL96122.1 - 6.2e-13 48.8 0.4 9e-13 48.2 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3052) FAD_binding_2 PF00890.24 ACL96122.1 - 0.0024 17.0 0.0 0.0041 16.3 0.0 1.3 2 0 0 2 2 2 1 FAD binding domain ECH_1 PF00378.20 ACL96123.1 - 5.1e-61 206.2 0.2 5.9e-61 205.9 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ACL96123.1 - 7.3e-30 104.6 3.4 2.7e-26 92.9 0.8 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Response_reg PF00072.24 ACL96124.1 - 3.5e-13 49.7 0.0 4.9e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain PrmC_N PF17827.1 ACL96124.1 - 0.13 12.9 0.0 0.27 11.9 0.0 1.6 1 0 0 1 1 1 0 PrmC N-terminal domain Putative_PNPOx PF01243.20 ACL96125.1 - 6.1e-18 64.8 0.0 1.1e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Peptidase_M16_C PF05193.21 ACL96126.1 - 2.4e-66 223.3 0.0 2.6e-34 118.9 0.0 2.8 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 ACL96126.1 - 4.7e-28 98.1 0.0 2.4e-16 60.1 0.0 2.3 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) Peptidase_M28 PF04389.17 ACL96127.2 - 6.2e-47 159.9 0.0 1e-46 159.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 ACL96127.2 - 2.9e-06 27.1 0.0 6e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 PA PF02225.22 ACL96127.2 - 2.4e-05 24.3 0.0 5.6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M42 PF05343.14 ACL96127.2 - 0.0027 16.8 0.0 0.0073 15.4 0.0 1.6 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase Nicastrin PF05450.15 ACL96127.2 - 0.2 11.1 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Nicastrin zf-dskA_traR PF01258.17 ACL96128.1 - 8.4e-14 51.2 0.2 1.5e-13 50.4 0.2 1.5 1 0 0 1 1 1 1 Prokaryotic dksA/traR C4-type zinc finger BssS PF13991.6 ACL96128.1 - 0.05 13.7 0.1 0.094 12.8 0.1 1.5 1 0 0 1 1 1 0 BssS protein family FliX PF10768.9 ACL96129.1 - 1.6e-43 148.5 0.8 1.8e-43 148.3 0.8 1.0 1 0 0 1 1 1 1 Class II flagellar assembly regulator SRP54_N PF02881.19 ACL96129.1 - 0.023 14.9 0.3 0.053 13.7 0.3 1.6 1 1 0 1 1 1 0 SRP54-type protein, helical bundle domain FlgI PF02119.16 ACL96130.1 - 4.2e-133 443.5 10.6 4.8e-133 443.4 10.6 1.0 1 0 0 1 1 1 1 Flagellar P-ring protein TOBE_2 PF08402.10 ACL96130.1 - 0.19 11.9 1.0 0.43 10.8 0.1 2.0 2 0 0 2 2 2 0 TOBE domain BAT PF15915.5 ACL96130.1 - 0.45 10.4 2.1 2.1 8.2 0.2 2.7 2 1 1 3 3 3 0 GAF and HTH_10 associated domain Rod-binding PF10135.9 ACL96131.1 - 6.6e-11 42.6 0.5 1.2e-10 41.8 0.5 1.4 1 0 0 1 1 1 1 Rod binding protein DALR_1 PF05746.15 ACL96132.1 - 0.058 13.6 1.6 0.088 13.0 1.2 1.6 1 1 1 2 2 2 0 DALR anticodon binding domain PrmA PF06325.13 ACL96133.1 - 4.1e-15 55.9 0.3 4.7e-15 55.8 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 ACL96133.1 - 1.5e-10 40.9 0.0 2.1e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 ACL96133.1 - 5.6e-10 39.8 0.1 7.8e-10 39.3 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 ACL96133.1 - 1.3e-07 31.5 0.0 2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 ACL96133.1 - 5e-06 26.4 0.0 6.1e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ACL96133.1 - 5.3e-06 27.0 0.0 7.7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ACL96133.1 - 6.3e-06 26.9 0.0 9.5e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 ACL96133.1 - 6.6e-05 22.7 0.0 9.1e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 ACL96133.1 - 0.00025 20.7 0.0 0.00037 20.2 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_23 PF13489.6 ACL96133.1 - 0.0042 16.9 0.0 0.0047 16.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain ASFV_J13L PF05568.11 ACL96133.1 - 0.038 13.8 0.2 0.054 13.3 0.2 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein Methyltransf_15 PF09445.10 ACL96133.1 - 0.064 12.8 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase DUF3422 PF11902.8 ACL96134.1 - 1.3e-109 367.1 0.0 1.5e-109 366.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3422) DUF2333 PF10095.9 ACL96134.1 - 0.034 13.2 0.5 0.15 11.1 0.5 1.9 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2333) ABC_tran PF00005.27 ACL96135.1 - 1.1e-42 145.8 0.0 1.3e-20 74.3 0.0 3.1 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 ACL96135.1 - 3.9e-15 56.4 8.8 0.00036 20.4 0.0 4.1 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ACL96135.1 - 9.8e-10 38.2 0.4 0.27 10.7 0.0 4.1 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ACL96135.1 - 3.9e-07 29.7 0.3 0.018 14.8 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ACL96135.1 - 9.9e-07 28.8 0.1 0.049 13.5 0.0 2.6 3 0 0 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 ACL96135.1 - 3.1e-06 27.2 0.1 0.0086 16.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 ACL96135.1 - 3.5e-05 24.4 1.8 0.14 12.7 0.3 2.4 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 ACL96135.1 - 0.00013 22.1 3.1 0.14 12.4 0.0 3.3 3 1 0 3 3 2 2 Putative exonuclease SbcCD, C subunit MeaB PF03308.16 ACL96135.1 - 0.00019 20.5 0.6 0.066 12.2 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 ACL96135.1 - 0.00077 19.7 0.4 2.3 8.5 0.0 3.6 4 1 0 4 4 4 1 AAA domain NB-ARC PF00931.22 ACL96135.1 - 0.0022 17.2 0.1 1 8.5 0.0 2.5 3 0 0 3 3 3 2 NB-ARC domain AAA_16 PF13191.6 ACL96135.1 - 0.0024 18.3 18.6 0.037 14.4 0.6 3.6 2 1 1 3 3 3 2 AAA ATPase domain NACHT PF05729.12 ACL96135.1 - 0.0033 17.4 0.6 1.6 8.6 0.1 2.7 3 0 0 3 3 2 1 NACHT domain NTPase_1 PF03266.15 ACL96135.1 - 0.0054 16.7 0.5 2.5 8.0 0.1 2.4 2 0 0 2 2 2 1 NTPase AAA_15 PF13175.6 ACL96135.1 - 0.015 15.0 0.5 1 9.0 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 ACL96135.1 - 0.018 15.5 0.1 5.7 7.4 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) DUF3693 PF12472.8 ACL96135.1 - 0.019 14.6 3.3 0.071 12.8 3.3 2.0 1 0 0 1 1 1 0 Phage related protein RNA_helicase PF00910.22 ACL96135.1 - 0.038 14.4 0.2 8 6.9 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 ACL96135.1 - 0.075 12.7 0.0 0.075 12.7 0.0 3.2 3 1 0 3 3 3 0 AAA domain AAA_18 PF13238.6 ACL96135.1 - 0.092 13.3 0.4 28 5.3 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ACL96135.1 - 0.094 12.9 4.5 1.9 8.6 0.0 3.3 3 1 0 3 3 3 0 AAA domain AAA_24 PF13479.6 ACL96135.1 - 0.1 12.3 0.1 11 5.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 ACL96135.1 - 0.17 11.9 0.2 4.5 7.3 0.0 2.3 2 0 0 2 2 2 0 Dynamin family DUF87 PF01935.17 ACL96135.1 - 0.17 11.9 0.2 22 5.1 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain Mg_chelatase PF01078.21 ACL96135.1 - 0.52 9.7 2.9 3.3 7.0 0.2 2.6 2 1 1 3 3 3 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 ACL96135.1 - 0.57 9.4 0.0 0.57 9.4 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin AAA_25 PF13481.6 ACL96135.1 - 0.68 9.5 6.3 2.3 7.8 0.2 3.1 3 0 0 3 3 3 0 AAA domain ABC_tran_Xtn PF12848.7 ACL96135.1 - 4 7.5 6.6 0.33 11.0 0.6 2.0 2 0 0 2 2 2 0 ABC transporter UvrA_DNA-bind PF17755.1 ACL96138.1 - 8e-38 129.2 0.0 4.6e-36 123.5 0.0 2.7 2 0 0 2 2 2 1 UvrA DNA-binding domain UvrA_inter PF17760.1 ACL96138.1 - 3.1e-37 127.0 0.1 9.8e-37 125.4 0.0 1.9 2 0 0 2 2 1 1 UvrA interaction domain ABC_tran PF00005.27 ACL96138.1 - 5e-20 72.4 0.0 4.1e-05 24.1 0.0 4.4 4 0 0 4 4 4 4 ABC transporter AAA_29 PF13555.6 ACL96138.1 - 8.9e-08 31.8 0.3 0.011 15.4 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 ACL96138.1 - 9.6e-08 31.7 0.0 0.049 13.1 0.0 4.1 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ACL96138.1 - 1.3e-05 25.7 0.0 0.0056 17.1 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.6 ACL96138.1 - 4.2e-05 23.2 0.0 0.054 13.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain DnaJ_CXXCXGXG PF00684.19 ACL96138.1 - 4.3e-05 23.8 1.1 0.036 14.4 0.3 3.3 3 0 0 3 3 3 1 DnaJ central domain ATPase PF06745.13 ACL96138.1 - 0.00075 18.9 0.1 0.32 10.3 0.2 2.3 2 0 0 2 2 2 2 KaiC RsgA_GTPase PF03193.16 ACL96138.1 - 0.0013 18.6 0.0 0.84 9.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 ACL96138.1 - 0.0014 18.5 4.7 0.031 14.1 0.0 4.0 5 0 0 5 5 5 1 AAA domain, putative AbiEii toxin, Type IV TA system APS_kinase PF01583.20 ACL96138.1 - 0.005 16.7 0.5 0.54 10.1 0.0 3.2 3 0 0 3 3 3 1 Adenylylsulphate kinase AAA_22 PF13401.6 ACL96138.1 - 0.0058 16.9 0.1 14 5.9 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 ACL96138.1 - 0.0088 16.6 0.0 7.8 7.1 0.0 3.2 3 0 0 3 3 2 1 AAA domain BCA_ABC_TP_C PF12399.8 ACL96138.1 - 0.026 14.4 0.8 0.17 11.8 0.1 2.4 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter AAA_33 PF13671.6 ACL96138.1 - 0.033 14.4 0.0 2.7 8.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 ACL96138.1 - 0.044 13.5 0.0 1.9 8.1 0.0 3.1 4 0 0 4 4 4 0 AAA ATPase domain AAA_23 PF13476.6 ACL96138.1 - 0.076 13.5 1.1 7.4 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ACL96138.1 - 0.11 12.4 0.0 24 4.8 0.0 2.7 3 0 0 3 3 3 0 NACHT domain MccV PF17508.2 ACL96138.1 - 0.12 12.9 0.1 7.5 7.2 0.0 2.8 3 0 0 3 3 2 0 Microcin V bacteriocin IstB_IS21 PF01695.17 ACL96138.1 - 0.15 11.8 0.2 13 5.5 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein Anti-TRAP PF15777.5 ACL96138.1 - 0.49 10.4 1.8 19 5.3 0.3 3.3 3 0 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF4096 PF13340.6 ACL96139.1 - 5.8e-21 74.5 4.2 1.3e-20 73.3 1.3 2.0 2 0 0 2 2 2 1 Putative transposase of IS4/5 family (DUF4096) TetR_C_20 PF17925.1 ACL96139.1 - 0.0085 16.4 1.7 0.011 16.0 1.7 1.2 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain EVI2A PF05399.11 ACL96139.1 - 0.018 14.6 0.2 0.026 14.1 0.2 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) DDE_Tnp_1_2 PF13586.6 ACL96140.1 - 1.6e-20 73.3 0.2 2.4e-20 72.7 0.2 1.3 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 ACL96140.1 - 1.6e-18 67.2 2.7 5.7e-17 62.1 2.7 2.0 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 ACL96140.1 - 1.9e-08 34.5 0.0 2.3e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 ACL96140.1 - 2.1e-05 24.3 0.0 2.4e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Anoctamin PF04547.12 ACL96141.1 - 0.002 17.0 0.0 0.0043 16.0 0.0 1.6 1 1 0 1 1 1 1 Calcium-activated chloride channel Sigma_reg_N PF13800.6 ACL96141.1 - 0.97 9.8 4.8 7.5 6.9 0.1 2.9 2 0 0 2 2 2 0 Sigma factor regulator N-terminal GST_N PF02798.20 ACL96142.1 - 3.1e-14 53.1 0.0 7.2e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ACL96142.1 - 2.7e-13 50.1 0.0 4.6e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ACL96142.1 - 1.7e-11 44.2 0.0 3.2e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ACL96142.1 - 3.6e-08 33.5 0.0 5.6e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ACL96142.1 - 8.2e-06 25.9 0.0 1.1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ACL96142.1 - 0.00013 21.9 0.3 0.00094 19.2 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_5 PF18485.1 ACL96142.1 - 0.057 13.8 0.0 0.097 13.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Calc_CGRP_IAPP PF00214.19 ACL96143.1 - 0.37 11.2 1.5 6.3 7.2 0.1 2.3 2 0 0 2 2 2 0 Calcitonin / CGRP / IAPP family GPDPase_memb PF10110.9 ACL96145.1 - 0.00078 18.3 4.9 0.00078 18.3 4.9 2.5 1 1 1 2 2 2 1 Membrane domain of glycerophosphoryl diester phosphodiesterase GIDA PF01134.22 ACL96146.1 - 4.3e-111 371.8 0.0 5.1e-111 371.5 0.0 1.0 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 ACL96146.1 - 0.00054 19.3 0.0 0.00094 18.5 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ACL96146.1 - 0.0013 18.4 0.5 0.017 14.7 0.2 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ACL96146.1 - 0.0035 17.5 0.1 0.0096 16.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 ACL96146.1 - 0.0054 16.1 0.1 0.0082 15.5 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ACL96146.1 - 0.027 13.5 0.6 0.047 12.8 0.2 1.5 2 0 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.18 ACL96146.1 - 0.035 14.0 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ACL96146.1 - 0.06 12.6 0.1 0.099 11.9 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 ACL96146.1 - 0.2 10.3 0.1 0.74 8.5 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein DUF1365 PF07103.11 ACL96147.1 - 1.9e-63 214.4 0.0 2.1e-63 214.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) Amino_oxidase PF01593.24 ACL96148.2 - 2.9e-23 82.9 1.9 4.8e-22 78.9 0.4 2.6 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ACL96148.2 - 1.8e-16 60.1 0.1 4.3e-16 58.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ACL96148.2 - 1.2e-09 38.2 1.2 6.2e-09 35.9 0.6 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ACL96148.2 - 0.00091 19.2 0.1 0.76 9.8 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 ACL96148.2 - 0.012 14.8 0.0 0.039 13.2 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ACL96148.2 - 0.015 14.6 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 ACL96148.2 - 0.015 14.4 1.0 0.026 13.6 1.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 ACL96148.2 - 0.047 12.4 0.0 0.08 11.6 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 ACL96148.2 - 0.06 13.9 0.1 0.24 12.0 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ACL96148.2 - 0.15 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CMAS PF02353.20 ACL96149.1 - 8.7e-39 133.5 0.0 1.1e-38 133.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 ACL96149.1 - 8.9e-16 58.4 0.0 5.4e-15 55.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ACL96149.1 - 1.2e-14 54.7 0.0 2.9e-14 53.5 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ACL96149.1 - 2e-14 53.8 0.0 2.9e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ACL96149.1 - 5.6e-13 49.0 0.0 8.2e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ACL96149.1 - 7.7e-12 45.8 0.0 1.7e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ACL96149.1 - 3.5e-09 36.5 0.0 6.3e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 ACL96149.1 - 5.5e-07 29.4 0.0 8.8e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) TehB PF03848.14 ACL96149.1 - 8.8e-06 25.3 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_4 PF02390.17 ACL96149.1 - 0.00028 20.4 0.0 0.0005 19.6 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase DUF938 PF06080.12 ACL96149.1 - 0.00038 20.3 0.0 0.00063 19.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) GidB PF02527.15 ACL96149.1 - 0.00041 19.7 0.0 0.0006 19.2 0.0 1.1 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltr_RsmB-F PF01189.17 ACL96149.1 - 0.0063 16.2 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F RrnaAD PF00398.20 ACL96149.1 - 0.0073 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_9 PF08003.11 ACL96149.1 - 0.05 12.5 0.0 0.075 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MetW PF07021.12 ACL96149.1 - 0.085 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW TRM13 PF05206.14 ACL96149.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase TRM13 PCMT PF01135.19 ACL96149.1 - 0.19 11.5 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF2177 PF09945.9 ACL96150.1 - 1.4e-46 157.6 9.1 1.6e-46 157.4 9.1 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2177) DUF1761 PF08570.10 ACL96150.1 - 0.096 13.0 6.9 0.22 11.8 6.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1761) Peptidase_M20 PF01546.28 ACL96151.1 - 6.1e-29 101.2 1.1 8.7e-29 100.7 1.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 ACL96151.1 - 4.1e-06 26.6 0.1 1e-05 25.3 0.1 1.7 2 0 0 2 2 2 1 Peptidase family M28 M20_dimer PF07687.14 ACL96151.1 - 0.00025 20.9 0.2 0.00097 19.0 0.2 2.0 1 0 0 1 1 1 1 Peptidase dimerisation domain Peripla_BP_3 PF13377.6 ACL96151.1 - 0.52 10.6 5.5 0.49 10.7 0.1 3.0 2 1 1 3 3 3 0 Periplasmic binding protein-like domain Aminotran_5 PF00266.19 ACL96152.1 - 1.7e-27 96.4 0.0 8e-27 94.2 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 ACL96152.1 - 0.00032 19.3 0.0 0.00051 18.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 ACL96152.1 - 0.039 13.2 0.2 0.057 12.7 0.2 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase SepSecS PF05889.13 ACL96152.1 - 0.15 10.7 0.1 1 8.0 0.0 1.9 1 1 0 2 2 2 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Polysacc_deac_1 PF01522.21 ACL96153.1 - 5.8e-14 52.1 0.1 3.3e-13 49.6 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide deacetylase OHCU_decarbox PF09349.10 ACL96154.1 - 2.1e-45 155.0 0.5 2.5e-45 154.7 0.5 1.1 1 0 0 1 1 1 1 OHCU decarboxylase Urate_ox_N PF06181.11 ACL96155.1 - 8e-130 432.5 13.2 1.1e-129 432.0 13.2 1.1 1 0 0 1 1 1 1 Urate oxidase N-terminal Cytochrome_CBB3 PF13442.6 ACL96155.1 - 3.7e-05 24.0 0.1 7.8e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 ACL96155.1 - 0.0014 19.8 0.6 0.0048 18.0 0.6 1.9 1 1 0 1 1 1 1 Cytochrome c Haem_bd PF14376.6 ACL96155.1 - 0.039 13.9 0.8 0.74 9.8 0.2 2.2 1 1 1 2 2 2 0 Haem-binding domain TetR_C_29 PF17938.1 ACL96156.1 - 1.3e-31 109.1 0.0 1.9e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_N PF00440.23 ACL96156.1 - 1.7e-11 43.7 0.9 2.9e-11 43.0 0.9 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_9 PF14514.6 ACL96156.1 - 0.00085 19.5 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_21 PF17926.1 ACL96156.1 - 0.005 17.0 0.2 0.016 15.4 0.0 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain DUF3941 PF13081.6 ACL96156.1 - 0.11 12.8 0.1 0.3 11.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3941) YceI PF04264.13 ACL96157.1 - 2.2e-40 138.6 0.0 2.5e-40 138.4 0.0 1.0 1 0 0 1 1 1 1 YceI-like domain LPAM_1 PF08139.12 ACL96157.1 - 0.12 12.9 0.8 0.23 12.0 0.8 1.5 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site HemolysinCabind PF00353.19 ACL96158.2 - 4.8e-68 224.5 191.4 9.5e-10 38.3 13.6 13.8 8 4 5 16 16 16 14 RTX calcium-binding nonapeptide repeat (4 copies) FmdA_AmdA PF03069.15 ACL96159.1 - 4.5e-41 140.9 0.0 1.2e-26 93.5 0.0 2.4 1 1 1 2 2 2 2 Acetamidase/Formamidase family Amidase PF01425.21 ACL96161.1 - 8e-105 351.4 0.1 1.7e-104 350.3 0.1 1.4 1 1 0 1 1 1 1 Amidase DUF3225 PF11533.8 ACL96162.1 - 1.5e-56 189.5 0.2 1.7e-56 189.4 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3225) SnoaL_3 PF13474.6 ACL96162.1 - 3.9e-05 23.9 0.3 5.6e-05 23.4 0.3 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 ACL96162.1 - 0.001 19.5 1.9 0.0014 19.0 1.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) DUF5609 PF18429.1 ACL96162.1 - 0.072 12.9 0.1 8 6.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5609) Lumazine_bd_2 PF12893.7 ACL96162.1 - 0.11 13.2 0.0 0.14 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative lumazine-binding IU_nuc_hydro PF01156.19 ACL96163.1 - 2.6e-79 267.0 0.9 3e-79 266.8 0.9 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase cNMP_binding PF00027.29 ACL96163.1 - 0.095 12.8 0.1 0.24 11.5 0.0 1.7 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain Amidohydro_1 PF01979.20 ACL96164.1 - 8.8e-67 225.8 0.1 1e-66 225.6 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ACL96164.1 - 3.5e-18 66.3 4.7 7.8e-14 52.0 0.1 2.2 1 1 1 2 2 2 2 Amidohydrolase family XdhC_C PF13478.6 ACL96165.1 - 2.3e-35 121.8 0.0 3.8e-35 121.1 0.0 1.4 1 0 0 1 1 1 1 XdhC Rossmann domain XdhC_CoxI PF02625.16 ACL96165.1 - 1.1e-19 70.4 1.3 2.6e-19 69.2 1.3 1.7 1 0 0 1 1 1 1 XdhC and CoxI family 2-Hacid_dh_C PF02826.19 ACL96165.1 - 0.0098 15.3 0.0 0.023 14.1 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ald_Xan_dh_C2 PF02738.18 ACL96166.1 - 1.8e-200 667.1 3.9 3e-200 666.4 3.9 1.3 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 ACL96166.1 - 6.3e-27 94.1 0.3 1.6e-26 92.8 0.3 1.8 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain FAD_binding_5 PF00941.21 ACL96167.1 - 9.1e-51 172.0 0.0 1.6e-50 171.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 ACL96167.1 - 1.2e-32 112.2 1.4 2.5e-32 111.1 1.4 1.6 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 ACL96167.1 - 8.5e-25 86.6 0.5 2e-24 85.4 0.5 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 ACL96167.1 - 6.5e-05 22.8 4.0 6.7e-05 22.8 0.4 2.5 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain Transthyretin PF00576.21 ACL96168.1 - 1.5e-30 106.1 0.0 1.7e-30 106.0 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family bMG3 PF11974.8 ACL96168.1 - 1.8e-05 24.7 0.0 2.7e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial alpha-2-macroglobulin MG3 domain CarboxypepD_reg PF13620.6 ACL96168.1 - 0.00052 20.2 0.0 0.00074 19.7 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Usher_TcfC PF17271.2 ACL96168.1 - 0.0015 17.4 0.0 0.0018 17.1 0.0 1.1 1 0 0 1 1 1 1 TcfC Usher-like barrel domain DUF4198 PF10670.9 ACL96168.1 - 0.081 13.3 0.1 0.12 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) MG4 PF17789.1 ACL96168.1 - 0.087 13.0 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Macroglobulin domain MG4 Big_1 PF02369.16 ACL96168.1 - 0.11 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) PTA_PTB PF01515.19 ACL96169.1 - 4.1e-80 269.5 0.0 5.5e-80 269.0 0.0 1.2 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase malic PF00390.19 ACL96169.1 - 1.2e-30 106.7 0.1 1.2e-28 100.2 0.1 2.3 1 1 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 ACL96169.1 - 4.7e-16 58.8 0.1 1.6e-15 57.1 0.1 1.8 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain Amidase_2 PF01510.25 ACL96169.1 - 0.018 15.5 0.0 0.039 14.4 0.0 1.5 1 0 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase ELFV_dehydrog PF00208.21 ACL96169.1 - 0.039 13.7 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase CSD PF00313.22 ACL96170.1 - 4.5e-22 77.7 0.0 4.8e-22 77.6 0.0 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 ACL96170.1 - 5.1e-06 26.1 0.6 1.5e-05 24.6 0.6 1.7 1 1 0 1 1 1 1 Ribonuclease B OB domain Rho_RNA_bind PF07497.12 ACL96170.1 - 0.019 14.9 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 Rho termination factor, RNA-binding domain Rrf2 PF02082.20 ACL96173.1 - 7.4e-24 83.9 0.1 1.2e-23 83.3 0.1 1.3 1 0 0 1 1 1 1 Transcriptional regulator MarR_2 PF12802.7 ACL96173.1 - 0.0073 16.2 0.6 0.019 14.9 0.6 1.6 1 0 0 1 1 1 1 MarR family TrmB PF01978.19 ACL96173.1 - 0.013 15.4 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HrcA_DNA-bdg PF03444.15 ACL96173.1 - 0.019 14.6 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding HTH_IclR PF09339.10 ACL96173.1 - 0.07 12.9 0.8 0.4 10.5 0.4 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain CBS PF00571.28 ACL96174.1 - 1.3e-24 86.4 1.6 1.1e-12 48.1 0.1 2.1 2 0 0 2 2 2 2 CBS domain XdhC_CoxI PF02625.16 ACL96174.1 - 0.034 14.3 0.2 0.099 12.9 0.2 1.8 1 1 0 1 1 1 0 XdhC and CoxI family Delta_lysin PF05372.11 ACL96174.1 - 0.47 9.8 0.2 0.47 9.8 0.2 1.9 2 0 0 2 2 2 0 Delta lysin family Rhomboid PF01694.22 ACL96175.1 - 1.3e-33 116.2 18.6 1.9e-33 115.6 18.6 1.2 1 0 0 1 1 1 1 Rhomboid family CsgG PF03783.14 ACL96177.1 - 1.8e-14 53.5 0.1 4.2e-14 52.3 0.1 1.5 1 1 0 1 1 1 1 Curli production assembly/transport component CsgG LPAM_1 PF08139.12 ACL96177.1 - 0.71 10.5 2.9 1.6 9.4 2.9 1.6 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site LPAM_2 PF13627.6 ACL96177.1 - 1 9.3 6.3 2.3 8.2 6.3 1.6 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site ABC_tran PF00005.27 ACL96179.1 - 1.2e-46 158.6 0.0 4.1e-22 79.2 0.0 2.9 2 0 0 2 2 2 2 ABC transporter ABC_tran_CTD PF16326.5 ACL96179.1 - 1.1e-16 60.8 7.0 1.1e-16 60.8 7.0 2.2 2 0 0 2 2 1 1 ABC transporter C-terminal domain AAA_21 PF13304.6 ACL96179.1 - 6.7e-16 59.0 4.6 0.00097 19.0 0.0 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ACL96179.1 - 1.7e-10 40.7 0.1 0.31 10.4 0.0 4.2 3 1 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ACL96179.1 - 1.7e-08 34.8 2.5 0.012 15.9 0.0 3.4 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 ACL96179.1 - 1.8e-07 31.2 0.3 0.007 16.3 0.1 2.8 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 ACL96179.1 - 1.9e-07 31.2 0.0 0.028 14.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 ACL96179.1 - 2.6e-07 30.3 0.0 0.012 15.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 ACL96179.1 - 1.1e-06 29.3 0.9 0.087 13.3 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 ACL96179.1 - 5.1e-06 26.9 0.1 0.015 15.7 0.0 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ACL96179.1 - 2.3e-05 24.4 0.3 0.0098 15.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 ACL96179.1 - 2.4e-05 24.2 0.0 0.083 12.6 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 ACL96179.1 - 2.8e-05 23.8 0.2 0.18 11.4 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 ACL96179.1 - 4e-05 23.4 0.8 0.37 10.5 0.0 2.8 3 0 0 3 3 2 2 AAA domain TsaE PF02367.17 ACL96179.1 - 5.6e-05 23.1 0.5 0.011 15.7 0.1 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 ACL96179.1 - 6.2e-05 23.2 0.0 0.039 14.2 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 ACL96179.1 - 6.6e-05 23.1 2.5 0.04 14.1 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 ACL96179.1 - 8.5e-05 22.8 2.2 0.34 11.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain NACHT PF05729.12 ACL96179.1 - 0.00012 22.0 0.2 0.23 11.3 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 ACL96179.1 - 0.0002 21.8 10.0 0.00036 21.0 0.4 3.4 2 2 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 ACL96179.1 - 0.00034 19.9 0.1 0.1 11.9 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_24 PF13479.6 ACL96179.1 - 0.00044 20.0 0.0 0.29 10.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ACL96179.1 - 0.00049 20.6 0.8 0.56 10.8 0.2 3.0 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 ACL96179.1 - 0.0016 18.8 0.0 1.1 9.7 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 ACL96179.1 - 0.0021 17.6 0.0 0.15 11.6 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region cobW PF02492.19 ACL96179.1 - 0.0027 17.3 0.4 0.34 10.5 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_13 PF13166.6 ACL96179.1 - 0.0056 15.4 0.7 3 6.4 0.0 2.7 3 0 0 3 3 3 2 AAA domain PduV-EutP PF10662.9 ACL96179.1 - 0.0057 16.4 0.2 1.5 8.5 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MobB PF03205.14 ACL96179.1 - 0.008 16.1 0.4 0.33 10.8 0.1 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.22 ACL96179.1 - 0.008 15.8 0.4 0.58 9.7 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Dynamin_N PF00350.23 ACL96179.1 - 0.01 15.9 0.0 3.6 7.6 0.0 2.7 3 0 0 3 3 2 0 Dynamin family NTPase_1 PF03266.15 ACL96179.1 - 0.013 15.5 3.2 0.26 11.2 0.1 3.3 4 0 0 4 4 4 0 NTPase DUF815 PF05673.13 ACL96179.1 - 0.019 14.2 0.2 2.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Arf PF00025.21 ACL96179.1 - 0.019 14.4 0.1 4.1 6.8 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF87 PF01935.17 ACL96179.1 - 0.022 14.9 0.1 1.6 8.8 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain RuvB_N PF05496.12 ACL96179.1 - 0.033 13.9 0.0 0.34 10.6 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Septin PF00735.18 ACL96179.1 - 0.042 13.1 0.0 5.2 6.3 0.0 2.2 2 0 0 2 2 2 0 Septin dNK PF01712.19 ACL96179.1 - 0.047 13.5 0.3 11 5.8 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase IstB_IS21 PF01695.17 ACL96179.1 - 0.053 13.3 0.1 7.5 6.2 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein A_thal_3526 PF09713.10 ACL96179.1 - 0.061 13.6 0.3 1.7 8.9 0.0 2.5 2 0 0 2 2 2 0 Plant protein 1589 of unknown function (A_thal_3526) NB-ARC PF00931.22 ACL96179.1 - 0.066 12.4 0.1 4 6.5 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.6 ACL96179.1 - 0.067 13.2 0.0 3 7.9 0.0 2.7 3 0 0 3 3 2 0 AAA domain CLP1_P PF16575.5 ACL96179.1 - 0.097 12.5 0.1 11 5.7 0.0 2.5 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Rad17 PF03215.15 ACL96179.1 - 0.12 12.3 0.0 6 6.7 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_19 PF13245.6 ACL96179.1 - 0.13 12.6 0.2 0.71 10.2 0.0 2.2 2 1 0 2 2 1 0 AAA domain MeaB PF03308.16 ACL96179.1 - 0.73 8.8 4.3 1.3 8.0 0.2 2.4 3 0 0 3 3 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB GAS PF13851.6 ACL96179.1 - 1.2 8.5 3.9 2.6 7.4 3.9 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding MASE1 PF05231.14 ACL96180.1 - 7.2e-50 169.8 37.5 9.2e-50 169.5 37.5 1.1 1 0 0 1 1 1 1 MASE1 Response_reg PF00072.24 ACL96180.1 - 4e-27 94.6 0.2 6.7e-27 93.9 0.2 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 ACL96180.1 - 1.3e-26 93.3 0.0 2.2e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ACL96180.1 - 3.4e-18 65.4 0.1 9.9e-18 64.0 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain NMT1 PF09084.11 ACL96181.1 - 9.2e-30 104.2 0.1 1.2e-29 103.8 0.1 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 ACL96181.1 - 0.00069 19.3 0.1 0.0025 17.5 0.0 1.9 1 1 0 2 2 2 1 ABC transporter, phosphonate, periplasmic substrate-binding protein LPAM_1 PF08139.12 ACL96181.1 - 0.012 16.0 1.1 0.012 16.0 1.1 2.1 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site ABC_tran PF00005.27 ACL96182.1 - 5e-28 98.3 0.0 6.9e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ACL96182.1 - 1.1e-06 28.6 0.0 0.0057 16.5 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ACL96182.1 - 1.8e-06 28.5 1.9 4.3e-06 27.2 1.9 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 ACL96182.1 - 8.5e-05 22.3 6.9 0.024 14.4 0.2 2.4 1 1 1 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 ACL96182.1 - 0.00028 20.8 0.0 0.00046 20.1 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 ACL96182.1 - 0.00055 20.2 0.0 0.0013 19.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 ACL96182.1 - 0.001 19.0 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain SbcCD_C PF13558.6 ACL96182.1 - 0.0015 18.7 0.3 0.0048 17.1 0.3 1.9 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 ACL96182.1 - 0.0073 16.5 0.2 0.097 12.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 ACL96182.1 - 0.015 15.6 0.2 0.084 13.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 ACL96182.1 - 0.023 14.1 0.0 3.3 7.1 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ACL96182.1 - 0.028 14.2 0.0 0.08 12.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 ACL96182.1 - 0.042 13.8 0.2 0.32 11.0 0.1 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 ACL96182.1 - 0.092 13.3 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ACL96182.1 - 0.096 12.8 0.0 0.28 11.3 0.0 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.29 ACL96182.1 - 0.13 12.7 0.1 0.41 11.1 0.1 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 ACL96182.1 - 0.23 11.5 0.0 1.3 9.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 ACL96182.1 - 0.33 11.4 0.0 0.44 11.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain BPD_transp_1 PF00528.22 ACL96183.1 - 9.2e-25 87.5 9.8 9.2e-25 87.5 9.8 1.8 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component HKR_ArcB_TM PF18415.1 ACL96183.1 - 1.6 9.6 5.8 0.6 10.9 2.7 1.9 2 0 0 2 2 2 0 Histidine kinase receptor ArcB trans-membrane domain DUF2336 PF10098.9 ACL96185.1 - 3.3e-66 223.4 20.7 3.3e-66 223.4 20.7 1.7 2 0 0 2 2 2 1 Uncharacterised protein conserved in bacteria (DUF2336) COMMD1_N PF17221.3 ACL96185.1 - 0.11 12.8 0.1 3.9 7.8 0.0 3.1 3 1 0 3 3 3 0 COMMD1 N-terminal domain Peptidase_M16_C PF05193.21 ACL96186.2 - 3.4e-37 128.3 0.0 3.6e-18 66.2 0.0 2.9 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 ACL96186.2 - 7.3e-29 100.7 0.0 2.8e-28 98.8 0.0 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) PAS_5 PF07310.13 ACL96188.2 - 2e-44 150.7 0.0 2.5e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 PAS domain Aldo_ket_red PF00248.21 ACL96189.1 - 4e-64 216.6 0.0 4.5e-64 216.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3606 PF12244.8 ACL96189.1 - 0.15 12.0 1.8 15 5.6 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3606) GMC_oxred_N PF00732.19 ACL96190.1 - 8.7e-94 314.2 0.0 1.3e-93 313.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ACL96190.1 - 7.1e-42 143.3 0.1 1.3e-41 142.5 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 ACL96190.1 - 1.5e-05 24.2 0.1 2.5e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 ACL96190.1 - 0.00014 21.1 1.7 0.0039 16.3 0.4 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 ACL96190.1 - 0.00015 21.9 1.2 0.00056 20.1 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ACL96190.1 - 0.00046 19.9 0.3 0.0084 15.7 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ACL96190.1 - 0.0026 17.1 0.4 0.011 15.0 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ACL96190.1 - 0.0035 16.6 0.0 0.0071 15.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 ACL96190.1 - 0.0089 14.8 0.2 0.023 13.4 0.2 1.6 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 ACL96190.1 - 0.18 10.8 0.2 0.44 9.6 0.2 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Hexapep PF00132.24 ACL96191.1 - 5.6e-17 60.7 12.8 1.2e-09 37.4 4.3 4.3 2 1 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 ACL96191.1 - 1.5e-07 31.1 15.2 9.8e-05 22.0 8.3 3.7 2 2 3 5 5 5 4 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 ACL96191.1 - 0.02 13.8 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 L-fucokinase DUF4954 PF16314.5 ACL96191.1 - 0.028 12.5 1.1 0.042 12.0 1.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) PhoH PF02562.16 ACL96192.1 - 4.2e-79 264.8 0.0 4.9e-79 264.6 0.0 1.0 1 0 0 1 1 1 1 PhoH-like protein AAA_30 PF13604.6 ACL96192.1 - 1.3e-09 38.1 0.0 2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ACL96192.1 - 7.8e-08 32.8 0.8 2.1e-07 31.4 0.1 2.0 2 1 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 ACL96192.1 - 3.7e-06 26.7 0.1 0.051 13.1 0.0 2.1 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain IstB_IS21 PF01695.17 ACL96192.1 - 0.0002 21.1 0.0 0.00052 19.8 0.0 1.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.6 ACL96192.1 - 0.0031 17.8 0.0 0.0084 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 ACL96192.1 - 0.0052 16.6 0.0 0.17 11.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Zot PF05707.12 ACL96192.1 - 0.0065 16.1 0.0 1.7 8.2 0.0 2.2 2 0 0 2 2 2 2 Zonular occludens toxin (Zot) AAA_25 PF13481.6 ACL96192.1 - 0.015 14.9 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 ACL96192.1 - 0.028 14.2 0.0 7.9 6.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 ACL96192.1 - 0.068 12.4 0.0 0.15 11.3 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 ACL96192.1 - 0.071 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 ACL96192.1 - 0.073 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Viral_helicase1 PF01443.18 ACL96192.1 - 0.12 12.1 0.0 0.46 10.2 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase OPT PF03169.15 ACL96194.1 - 4e-98 329.7 47.9 5.9e-98 329.1 47.9 1.2 1 0 0 1 1 1 1 OPT oligopeptide transporter protein COX8 PF02285.15 ACL96194.1 - 0.082 12.8 0.7 0.54 10.2 0.7 2.5 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIII GCSF PF16647.5 ACL96194.1 - 0.18 11.7 2.0 0.5 10.2 2.0 1.7 1 1 0 1 1 1 0 Granulocyte colony-stimulating factor FHIPEP PF00771.20 ACL96194.1 - 0.35 9.3 4.7 0.6 8.5 4.7 1.3 1 0 0 1 1 1 0 FHIPEP family GST_N_3 PF13417.6 ACL96195.1 - 3.4e-14 53.0 0.0 5.6e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ACL96195.1 - 7.1e-12 45.5 0.0 1.1e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ACL96195.1 - 8.9e-09 35.5 0.0 2e-08 34.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ACL96195.1 - 3.1e-07 30.3 2.7 5.2e-07 29.6 1.0 2.2 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ACL96195.1 - 1.1e-06 28.7 0.0 1.7e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 ACL96195.1 - 0.023 15.4 0.0 0.038 14.7 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_C_3 PF14497.6 ACL96195.1 - 0.025 14.8 0.0 0.036 14.2 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain FR47 PF08445.10 ACL96196.2 - 9.9e-20 70.3 0.0 1.5e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 ACL96196.2 - 9.9e-16 58.0 0.0 2e-15 57.0 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ACL96196.2 - 2.3e-11 44.0 0.1 3.6e-11 43.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ACL96196.2 - 5.2e-09 36.1 0.0 7.9e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ACL96196.2 - 3.1e-07 30.5 0.0 1.3e-06 28.5 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ACL96196.2 - 0.0011 19.0 0.0 0.0019 18.3 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 ACL96196.2 - 0.0015 19.2 0.0 0.0021 18.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 ACL96196.2 - 0.0025 17.4 0.0 0.0035 16.9 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_8 PF13523.6 ACL96196.2 - 0.032 13.9 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 ACL96196.2 - 0.11 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase DUF3126 PF11324.8 ACL96197.1 - 2.3e-27 94.6 0.1 2.6e-27 94.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3126) Glu_cyclase_2 PF05096.12 ACL96198.1 - 2.6e-96 321.9 0.0 3.1e-96 321.7 0.0 1.0 1 0 0 1 1 1 1 Glutamine cyclotransferase SATase_N PF06426.14 ACL96199.1 - 4.1e-37 126.7 1.8 6.3e-37 126.2 1.8 1.3 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep PF00132.24 ACL96199.1 - 4.1e-13 48.5 7.6 1.3e-08 34.2 0.3 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 ACL96199.1 - 8e-05 22.3 0.8 8e-05 22.3 0.8 2.9 2 1 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase NUDIX PF00293.28 ACL96200.1 - 1.5e-12 47.7 0.0 2.5e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.6 ACL96200.1 - 0.29 10.7 0.0 0.4 10.2 0.0 1.1 1 0 0 1 1 1 0 Nucleotide hydrolase Nitroreductase PF00881.24 ACL96201.1 - 1e-22 81.0 0.1 1.4e-22 80.5 0.1 1.2 1 0 0 1 1 1 1 Nitroreductase family QueF PF14489.6 ACL96202.1 - 3e-32 110.6 0.0 4e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 QueF-like protein QueF_N PF14819.6 ACL96202.1 - 0.00021 21.5 0.0 0.00028 21.2 0.0 1.3 1 0 0 1 1 1 1 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term adh_short_C2 PF13561.6 ACL96203.1 - 2.6e-54 184.3 6.7 3.2e-54 183.9 6.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ACL96203.1 - 1.5e-46 158.4 1.3 1.9e-46 158.0 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ACL96203.1 - 2.7e-15 56.7 2.0 3.9e-15 56.2 2.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ACL96203.1 - 0.00091 18.8 1.1 0.0025 17.3 1.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family LDcluster4 PF18306.1 ACL96203.1 - 0.021 14.4 4.1 0.49 10.0 0.2 2.3 2 0 0 2 2 2 0 SLOG cluster4 family CoA_binding_2 PF13380.6 ACL96203.1 - 0.061 13.8 0.1 0.14 12.6 0.1 1.6 1 0 0 1 1 1 0 CoA binding domain rve PF00665.26 ACL96204.1 - 9e-33 113.0 0.0 1.4e-32 112.3 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain HTH_32 PF13565.6 ACL96204.1 - 5.5e-16 58.9 0.7 1.9e-15 57.2 0.1 2.3 2 0 0 2 2 2 1 Homeodomain-like domain rve_3 PF13683.6 ACL96204.1 - 3.6e-15 55.5 0.5 6.9e-15 54.6 0.5 1.5 1 0 0 1 1 1 1 Integrase core domain HTH_28 PF13518.6 ACL96204.1 - 3e-10 40.1 0.8 1.4e-09 37.9 0.0 2.4 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_29 PF13551.6 ACL96204.1 - 3.1e-07 30.3 0.0 2.5e-06 27.4 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 ACL96204.1 - 5.1e-07 29.3 7.0 1.2e-06 28.2 0.0 3.7 4 0 0 4 4 4 1 Homeodomain-like domain HTH_Tnp_1 PF01527.20 ACL96204.1 - 4e-06 27.1 0.0 2e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 Transposase LZ_Tnp_IS481 PF13011.6 ACL96204.1 - 5.2e-06 26.9 0.0 1.2e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 leucine-zipper of insertion element IS481 DDE_Tnp_IS240 PF13610.6 ACL96204.1 - 0.00016 21.9 0.0 0.001 19.3 0.0 2.3 2 1 0 2 2 2 1 DDE domain CENP-B_N PF04218.13 ACL96204.1 - 0.008 15.8 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HU-CCDC81_bac_1 PF18174.1 ACL96204.1 - 0.0088 15.9 0.0 0.051 13.5 0.0 2.1 2 0 0 2 2 2 1 CCDC81-like prokaryotic HU domain 1 HTH_Tnp_1 PF01527.20 ACL96205.1 - 4.6e-10 39.7 0.2 1e-09 38.6 0.2 1.7 1 1 0 1 1 1 1 Transposase HTH_28 PF13518.6 ACL96205.1 - 0.0029 17.7 0.1 0.0052 16.9 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Cas_Cas1 PF01867.16 ACL96205.1 - 0.099 11.8 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 CRISPR associated protein Cas1 COMP PF11598.8 ACL96205.1 - 0.28 11.7 2.2 0.32 11.5 0.8 1.9 2 1 0 2 2 2 0 Cartilage oligomeric matrix protein Gcw_chp PF09694.10 ACL96206.1 - 8.8e-36 124.0 8.4 1e-35 123.8 8.4 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (Gcw_chp) MFS_1 PF07690.16 ACL96207.1 - 2.8e-17 62.7 57.9 2.9e-09 36.3 32.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TonB_dep_Rec PF00593.24 ACL96208.1 - 1.3e-28 101.1 34.1 1.3e-28 101.1 34.1 2.0 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 ACL96208.1 - 5.2e-07 30.2 0.0 1.3e-06 29.0 0.0 1.7 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain FCD PF07729.12 ACL96209.2 - 4.2e-22 78.9 9.3 4.2e-22 78.9 9.3 1.7 1 1 1 2 2 2 1 FCD domain GntR PF00392.21 ACL96209.2 - 4e-14 52.0 0.5 8.4e-14 51.0 0.5 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family TetR_N PF00440.23 ACL96210.1 - 7e-10 38.5 0.7 1.2e-08 34.6 0.1 2.4 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family CsgG PF03783.14 ACL96210.1 - 0.028 13.7 0.2 0.091 12.0 0.1 1.7 2 0 0 2 2 2 0 Curli production assembly/transport component CsgG AMO PF02461.16 ACL96211.3 - 0.0026 17.6 2.5 0.0053 16.6 2.5 1.5 1 0 0 1 1 1 1 Ammonia monooxygenase Lipoprotein_9 PF03180.14 ACL96212.2 - 5.9e-98 326.7 0.9 6.7e-98 326.5 0.9 1.0 1 0 0 1 1 1 1 NLPA lipoprotein Phosphonate-bd PF12974.7 ACL96212.2 - 0.00022 20.9 0.1 0.00077 19.1 0.1 1.9 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein BPD_transp_1 PF00528.22 ACL96215.1 - 6.5e-18 65.1 16.7 6.5e-18 65.1 16.7 1.3 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component EII-GUT PF03608.13 ACL96215.1 - 1.1 9.1 8.6 7.9 6.4 1.8 2.7 2 1 1 3 3 3 0 PTS system enzyme II sorbitol-specific factor FtsX PF02687.21 ACL96215.1 - 8.3 7.0 16.0 0.38 11.2 3.3 2.4 2 0 0 2 2 2 0 FtsX-like permease family ABC_tran PF00005.27 ACL96216.1 - 6.3e-36 123.9 0.0 8.7e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter NIL PF09383.10 ACL96216.1 - 5.8e-18 64.5 0.0 1.3e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 NIL domain AAA_21 PF13304.6 ACL96216.1 - 1.3e-06 28.5 0.1 0.024 14.5 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ACL96216.1 - 0.00014 21.4 0.4 0.0026 17.2 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ACL96216.1 - 0.00019 21.7 0.1 0.015 15.6 0.3 2.9 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ACL96216.1 - 0.00039 20.2 1.7 0.081 12.6 1.4 2.9 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ACL96216.1 - 0.0062 16.2 0.3 0.014 15.2 0.3 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ACL96216.1 - 0.012 15.5 0.2 0.025 14.5 0.2 1.5 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 ACL96216.1 - 0.013 14.8 0.2 0.21 10.9 0.1 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.6 ACL96216.1 - 0.034 14.5 1.2 0.11 12.9 0.8 2.0 2 1 0 2 2 2 0 AAA ATPase domain TniB PF05621.11 ACL96216.1 - 0.069 12.5 0.1 0.41 10.0 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein SbcCD_C PF13558.6 ACL96216.1 - 0.077 13.2 0.3 0.58 10.4 0.3 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 ACL96216.1 - 0.089 12.9 0.1 0.21 11.7 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_ATPase PF09818.9 ACL96216.1 - 0.11 11.3 1.4 8.8 5.0 0.0 2.8 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA PF00004.29 ACL96216.1 - 0.14 12.6 0.0 3.9 7.9 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 ACL96216.1 - 0.15 12.1 0.3 0.26 11.3 0.3 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain HATPase_c PF02518.26 ACL96217.1 - 2.7e-28 98.7 0.2 4.9e-28 97.9 0.2 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ACL96217.1 - 3.1e-26 91.7 0.2 7.5e-26 90.5 0.2 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ACL96217.1 - 3.5e-19 68.6 0.1 3.5e-19 68.6 0.1 2.4 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 ACL96217.1 - 2.6e-14 53.7 0.2 8.2e-14 52.1 0.2 1.9 1 0 0 1 1 1 1 GAF domain PAS_4 PF08448.10 ACL96217.1 - 2.8e-08 34.0 0.1 7.1e-08 32.7 0.1 1.8 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 ACL96217.1 - 4.7e-08 33.2 0.0 9e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold GAF PF01590.26 ACL96217.1 - 2.6e-07 31.3 0.0 5.9e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 GAF domain PAS_9 PF13426.7 ACL96217.1 - 2.6e-06 27.6 0.0 1e-05 25.7 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 ACL96217.1 - 8.8e-06 25.7 0.0 1.9e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 ACL96217.1 - 0.00036 20.5 0.1 0.0027 17.7 0.0 2.5 3 0 0 3 3 3 1 PAS domain HATPase_c_2 PF13581.6 ACL96217.1 - 0.03 14.3 0.0 0.03 14.3 0.0 2.4 3 0 0 3 3 3 0 Histidine kinase-like ATPase domain DUF4164 PF13747.6 ACL96217.1 - 0.72 10.2 10.0 0.041 14.2 2.6 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) Peptidase_S9 PF00326.21 ACL96218.1 - 2.8e-27 95.6 0.6 4.5e-27 94.9 0.6 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 ACL96218.1 - 2.1e-07 30.7 0.9 0.0051 16.7 0.0 4.2 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat DLH PF01738.18 ACL96218.1 - 1.3e-06 28.2 0.1 2.1e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 ACL96218.1 - 0.00047 19.5 0.2 0.18 11.0 0.2 2.6 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ACL96218.1 - 0.00048 20.8 2.1 0.00048 20.8 2.1 4.0 2 1 2 4 4 4 1 Alpha/beta hydrolase family NAGPA PF09992.9 ACL96218.1 - 0.026 14.7 0.0 0.44 10.7 0.0 2.4 2 0 0 2 2 2 0 Phosphodiester glycosidase Abhydrolase_2 PF02230.16 ACL96218.1 - 0.051 13.4 0.0 0.28 10.9 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase AXE1 PF05448.12 ACL96218.1 - 0.063 11.9 0.0 0.11 11.1 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 ACL96218.1 - 0.098 12.5 1.4 2.5 7.9 0.7 2.9 1 1 0 2 2 2 0 alpha/beta hydrolase fold FSH1 PF03959.13 ACL96218.1 - 0.21 11.2 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) PAF-AH_p_II PF03403.13 ACL96218.1 - 0.29 9.6 0.1 0.44 9.0 0.1 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Amidohydro_1 PF01979.20 ACL96219.1 - 6.6e-61 206.5 0.3 8.4e-61 206.2 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ACL96219.1 - 7.5e-13 48.7 7.5 1.9e-07 30.9 1.8 2.7 1 1 2 3 3 3 2 Amidohydrolase family AP_endonuc_2 PF01261.24 ACL96219.1 - 0.00023 20.6 0.0 0.00074 19.0 0.0 1.9 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel HMGL-like PF00682.19 ACL96219.1 - 0.013 15.1 0.1 0.044 13.3 0.0 1.9 2 0 0 2 2 2 0 HMGL-like GHL6 PF14871.6 ACL96219.1 - 0.053 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 HTH_31 PF13560.6 ACL96220.2 - 3.4e-09 36.9 0.1 6.4e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 ACL96220.2 - 1.2e-08 34.9 0.0 1.8e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 ACL96220.2 - 6.7e-08 32.4 0.0 1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 ACL96220.2 - 0.029 14.8 0.0 0.051 14.0 0.0 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain YdaS_antitoxin PF15943.5 ACL96220.2 - 0.043 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Pou PF00157.17 ACL96220.2 - 0.056 13.4 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain Crp PF00325.20 ACL96220.2 - 0.074 12.7 0.6 0.65 9.7 0.3 2.7 2 1 0 2 2 2 0 Bacterial regulatory proteins, crp family HTH_25 PF13413.6 ACL96220.2 - 0.11 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain MoCF_biosynth PF00994.24 ACL96221.1 - 7.5e-35 119.7 0.1 1.1e-34 119.1 0.1 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain SfsA PF03749.13 ACL96222.1 - 4.5e-46 156.2 0.0 5.7e-46 155.9 0.0 1.1 1 0 0 1 1 1 1 Sugar fermentation stimulation protein RE domain SfsA_N PF17746.1 ACL96222.1 - 5.5e-20 71.3 0.0 1e-19 70.4 0.0 1.5 1 0 0 1 1 1 1 SfsA N-terminal OB domain DUF4995 PF16386.5 ACL96223.1 - 0.16 11.9 0.1 0.69 9.9 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function Peptidase_M24 PF00557.24 ACL96224.1 - 4.8e-52 176.7 0.0 5.6e-52 176.5 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 RPAP1_C PF08620.10 ACL96224.1 - 0.018 15.1 0.0 0.038 14.1 0.0 1.6 1 0 0 1 1 1 0 RPAP1-like, C-terminal DUF3325 PF11804.8 ACL96225.1 - 0.0052 16.9 0.1 0.0076 16.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3325) DUF5472 PF17566.2 ACL96225.1 - 0.075 13.0 0.1 0.1 12.6 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5472) HicB PF05534.12 ACL96226.1 - 0.082 12.8 0.0 0.24 11.3 0.0 1.7 2 0 0 2 2 2 0 HicB family RadC PF04002.15 ACL96227.1 - 2.4e-23 82.4 0.0 3.9e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 RadC-like JAB domain HHH_2 PF12826.7 ACL96227.1 - 1.4e-06 28.2 0.0 2.4e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 ACL96227.1 - 0.0019 18.7 0.1 0.0037 17.9 0.1 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 ACL96227.1 - 0.0087 15.9 0.1 0.017 14.9 0.1 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif Phage_integrase PF00589.22 ACL96228.2 - 4.3e-09 36.4 0.0 9.5e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 Phage integrase family Arm-DNA-bind_3 PF13356.6 ACL96228.2 - 0.00038 20.8 0.1 0.00038 20.8 0.1 2.1 3 0 0 3 3 3 1 Arm DNA-binding domain DUF736 PF05284.12 ACL96230.1 - 4.1e-27 94.0 0.0 4.8e-27 93.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF736) DUF2274 PF10038.9 ACL96231.1 - 2.2e-24 85.7 0.2 3.3e-24 85.1 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2274) SRP1_TIP1 PF00660.17 ACL96231.1 - 0.18 11.9 0.0 0.22 11.6 0.0 1.1 1 0 0 1 1 1 0 Seripauperin and TIP1 family rve_2 PF13333.6 ACL96231.1 - 0.18 12.0 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain TrbI PF03743.14 ACL96232.1 - 8.4e-54 182.3 0.7 1.3e-53 181.7 0.7 1.3 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein CagX PF03524.15 ACL96233.1 - 5e-66 222.4 0.0 6e-66 222.2 0.0 1.1 1 0 0 1 1 1 1 Conjugal transfer protein VirB8 PF04335.13 ACL96234.1 - 5.9e-65 219.1 1.5 7e-65 218.9 1.5 1.0 1 0 0 1 1 1 1 VirB8 protein XPB_DRD PF18458.1 ACL96234.1 - 0.072 13.0 0.3 0.35 10.8 0.1 2.2 2 0 0 2 2 2 0 Xeroderma pigmentosum group B helicase damage recognition domain TrbL PF04610.14 ACL96235.1 - 2.7e-48 164.6 22.8 2.7e-48 164.6 22.8 2.1 2 1 0 2 2 2 1 TrbL/VirB6 plasmid conjugal transfer protein HTH_Tnp_1 PF01527.20 ACL96236.1 - 6.3e-22 77.7 0.3 7.5e-22 77.4 0.3 1.1 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 ACL96236.1 - 6.7e-05 22.9 0.1 0.00016 21.7 0.1 1.8 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 ACL96236.1 - 0.00034 20.3 0.1 0.00084 19.1 0.1 1.8 1 1 0 1 1 1 1 Homeodomain-like domain HTH_11 PF08279.12 ACL96236.1 - 0.0013 18.7 0.1 0.003 17.5 0.0 1.6 2 0 0 2 2 2 1 HTH domain HTH_29 PF13551.6 ACL96236.1 - 0.0045 17.0 0.1 0.013 15.5 0.1 2.0 1 1 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_1_2 PF13022.6 ACL96236.1 - 0.0058 16.8 0.1 0.013 15.7 0.1 1.6 1 1 0 1 1 1 1 Helix-turn-helix of insertion element transposase CENP-B_N PF04218.13 ACL96236.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_AsnC-type PF13404.6 ACL96236.1 - 0.02 14.7 0.1 0.09 12.6 0.0 2.1 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_psq PF05225.16 ACL96236.1 - 0.027 14.2 0.2 2.1 8.2 0.0 2.3 1 1 1 2 2 2 0 helix-turn-helix, Psq domain Terminase_5 PF06056.12 ACL96236.1 - 0.035 14.0 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_24 PF13412.6 ACL96236.1 - 0.047 13.3 2.3 0.19 11.3 0.0 2.7 3 1 1 4 4 4 0 Winged helix-turn-helix DNA-binding MerR PF00376.23 ACL96236.1 - 0.08 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 MerR family regulatory protein YdaS_antitoxin PF15943.5 ACL96236.1 - 0.1 12.5 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT MerR_1 PF13411.6 ACL96236.1 - 0.11 12.6 0.0 0.3 11.2 0.0 1.9 2 1 0 2 2 2 0 MerR HTH family regulatory protein rve_3 PF13683.6 ACL96237.1 - 4.2e-32 109.7 0.1 1e-31 108.5 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain rve PF00665.26 ACL96237.1 - 1.6e-23 83.2 0.0 2.8e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 ACL96237.1 - 1.6e-09 37.7 6.5 3.8e-09 36.5 6.5 1.6 1 0 0 1 1 1 1 HTH-like domain rve_2 PF13333.6 ACL96237.1 - 0.0013 18.8 0.0 0.0026 17.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain HTH_32 PF13565.6 ACL96237.1 - 4.6 7.9 15.2 2.9 8.6 2.3 3.6 2 1 1 4 4 4 0 Homeodomain-like domain MCPsignal PF00015.21 ACL96238.1 - 6.8e-54 182.3 21.6 1.3e-53 181.3 21.6 1.5 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Focal_AT PF03623.13 ACL96238.1 - 0.15 12.0 3.1 0.37 10.8 2.9 1.7 1 1 1 2 2 2 0 Focal adhesion targeting region Uso1_p115_C PF04871.13 ACL96238.1 - 0.18 12.2 2.5 0.16 12.4 0.4 1.9 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3130 PF11328.8 ACL96238.1 - 0.18 12.0 1.7 0.53 10.6 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3130 MtrF PF09472.10 ACL96238.1 - 0.31 10.5 3.0 1.2 8.6 0.1 2.7 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DASH_Duo1 PF08651.10 ACL96238.1 - 0.74 9.6 3.3 0.81 9.5 1.1 2.0 2 0 0 2 2 2 0 DASH complex subunit Duo1 Laminin_II PF06009.12 ACL96238.1 - 5.3 7.1 13.9 3.1 7.8 7.0 2.7 2 1 0 2 2 2 0 Laminin Domain II GATase_3 PF07685.14 ACL96241.1 - 1.1e-56 191.6 0.0 1.5e-56 191.1 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.23 ACL96241.1 - 5.2e-16 58.9 0.0 7.8e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 ACL96241.1 - 1.4e-15 57.7 0.0 5.1e-15 55.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain DUF2235 PF09994.9 ACL96244.2 - 4.5e-69 233.0 0.0 5.4e-69 232.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) LysM PF01476.20 ACL96244.2 - 9.5e-10 38.4 0.0 2e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 LysM domain Guanylate_cyc PF00211.20 ACL96248.2 - 2.6e-10 40.2 0.0 0.0003 20.4 0.0 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain TIR-like PF10137.9 ACL96250.1 - 4.8e-35 120.1 0.0 1.4e-34 118.5 0.0 1.7 2 0 0 2 2 2 1 Predicted nucleotide-binding protein containing TIR-like domain cNMP_binding PF00027.29 ACL96250.1 - 6.3e-14 51.8 0.0 1.1e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Guanylate_cyc PF00211.20 ACL96251.1 - 8.3e-07 28.8 0.0 1.1e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HTH_3 PF01381.22 ACL96253.1 - 2.6e-15 56.2 0.1 3.1e-15 55.9 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 ACL96253.1 - 4.9e-13 49.2 0.7 6.7e-13 48.8 0.7 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 ACL96253.1 - 9.8e-09 35.1 0.1 1.1e-08 35.0 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 ACL96253.1 - 7.4e-06 26.3 0.0 8.7e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 ACL96253.1 - 0.00016 21.4 0.0 0.00049 19.9 0.0 1.7 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_37 PF13744.6 ACL96253.1 - 0.00018 21.4 0.0 0.00024 21.0 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 ACL96254.1 - 7.8e-16 58.2 0.9 9.5e-16 57.9 0.9 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 ACL96254.1 - 8.6e-16 57.7 0.0 9.6e-16 57.6 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 ACL96254.1 - 5.2e-09 36.0 0.0 6.2e-09 35.8 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 ACL96254.1 - 3.8e-06 27.2 0.0 4.4e-06 27.0 0.0 1.0 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_25 PF13413.6 ACL96254.1 - 0.00068 19.4 0.0 0.0018 18.1 0.0 1.8 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 ACL96254.1 - 0.0077 16.2 0.0 0.0096 15.9 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain MqsA_antitoxin PF15731.5 ACL96254.1 - 0.12 12.5 0.0 0.12 12.5 0.0 1.0 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA Sigma70_r4_2 PF08281.12 ACL96255.2 - 3.5e-13 49.0 0.1 5.5e-13 48.4 0.1 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 ACL96255.2 - 1.8e-09 37.2 1.6 3e-09 36.5 1.6 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 ACL96255.2 - 6.4e-08 32.0 0.0 1.1e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 ACL96255.2 - 0.0029 17.5 0.0 0.004 17.0 0.0 1.2 1 0 0 1 1 1 1 ECF sigma factor HTH_24 PF13412.6 ACL96255.2 - 0.024 14.2 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF1318 PF07027.12 ACL96255.2 - 0.16 12.5 0.0 0.26 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1318) Phage_antitermQ PF06530.12 ACL96255.2 - 0.17 11.8 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Phage antitermination protein Q FecR PF04773.13 ACL96256.1 - 6.8e-22 77.9 2.6 1.1e-21 77.3 1.7 1.8 2 0 0 2 2 2 1 FecR protein DUF4880 PF16220.5 ACL96256.1 - 6.3e-07 29.2 0.7 3.2e-06 26.9 0.7 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4880) TonB_dep_Rec PF00593.24 ACL96257.1 - 1.5e-42 147.1 9.5 1.5e-42 147.1 9.5 2.1 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 ACL96257.1 - 4.8e-22 78.6 2.4 1.4e-21 77.1 2.4 1.8 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain STN PF07660.14 ACL96257.1 - 3.5e-05 23.5 0.0 0.00014 21.6 0.0 2.2 1 0 0 1 1 1 1 Secretin and TonB N terminus short domain Peptidase_S9 PF00326.21 ACL96258.1 - 7.1e-33 113.9 0.0 6.4e-32 110.8 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 ACL96258.1 - 1.1e-06 28.5 0.4 0.00018 21.2 0.8 3.0 2 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 ACL96258.1 - 0.00031 20.5 0.0 0.0078 15.9 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ACL96258.1 - 0.00053 19.3 0.2 0.0024 17.2 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DLH PF01738.18 ACL96258.1 - 0.00066 19.3 0.0 0.9 9.1 0.1 2.7 2 1 0 2 2 2 2 Dienelactone hydrolase family Esterase PF00756.20 ACL96258.1 - 0.0017 18.0 0.2 0.0048 16.6 0.0 1.8 2 0 0 2 2 2 1 Putative esterase PAF-AH_p_II PF03403.13 ACL96258.1 - 0.0021 16.6 0.0 0.0032 16.1 0.0 1.1 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II AXE1 PF05448.12 ACL96258.1 - 0.0037 16.0 0.0 0.01 14.5 0.0 1.6 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 ACL96258.1 - 0.0074 16.2 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal GGDEF_2 PF17853.1 ACL96258.1 - 0.028 14.7 0.3 2.7 8.3 0.0 3.7 4 0 0 4 4 4 0 GGDEF-like domain Asn_synthase PF00733.21 ACL96259.1 - 7.9e-35 121.2 0.0 1e-34 120.8 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.13 ACL96259.1 - 0.14 11.6 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Transglut_core3 PF13471.6 ACL96260.1 - 1.1e-19 70.4 2.4 1.7e-19 69.8 2.4 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily GntR PF00392.21 ACL96263.1 - 2.3e-10 40.0 0.4 5.1e-10 38.8 0.4 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family MarR_2 PF12802.7 ACL96263.1 - 0.0049 16.7 1.1 0.021 14.7 1.1 2.1 1 1 0 1 1 1 1 MarR family HTH_24 PF13412.6 ACL96263.1 - 0.0094 15.5 0.0 0.061 12.9 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_3 PF01381.22 ACL96265.1 - 0.002 18.1 0.0 0.0033 17.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 ACL96265.1 - 0.0029 17.9 0.0 0.0051 17.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain DUF2285 PF10074.9 ACL96266.1 - 7.4e-18 65.2 1.4 7.4e-18 65.2 1.4 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2285) DUF2285 PF10074.9 ACL96267.1 - 9.1e-09 35.9 3.1 1.1e-08 35.7 3.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2285) MelC1 PF06236.11 ACL96270.2 - 0.067 13.3 0.9 0.088 12.9 0.9 1.3 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 OEP PF02321.18 ACL96271.1 - 1.1e-40 139.5 41.9 2.4e-23 82.9 14.4 2.0 2 0 0 2 2 2 2 Outer membrane efflux protein Herpes_UL25 PF01499.16 ACL96271.1 - 1.7 7.1 12.9 0.028 13.0 4.3 2.1 2 0 0 2 2 2 0 Herpesvirus UL25 family HlyD_D23 PF16576.5 ACL96272.1 - 3.8e-21 75.3 0.7 7e-21 74.4 0.7 1.4 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 ACL96272.1 - 1.4e-19 70.8 4.6 1.3e-14 54.8 0.4 3.5 2 2 1 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 ACL96272.1 - 2.7e-07 30.3 0.1 0.0028 17.5 0.0 2.9 2 0 0 2 2 2 2 Biotin-lipoyl like HlyD PF00529.20 ACL96272.1 - 2.5e-05 24.1 7.5 0.0017 18.2 0.5 2.8 2 1 0 2 2 2 2 HlyD membrane-fusion protein of T1SS DUF2254 PF10011.9 ACL96272.1 - 0.00049 19.0 0.1 0.0019 17.1 0.1 1.8 2 0 0 2 2 2 1 Predicted membrane protein (DUF2254) PYNP_C PF07831.13 ACL96272.1 - 0.0032 17.1 0.1 0.026 14.2 0.0 2.5 3 0 0 3 3 3 1 Pyrimidine nucleoside phosphorylase C-terminal domain Biotin_lipoyl PF00364.22 ACL96272.1 - 0.0046 16.7 0.0 0.18 11.6 0.0 2.5 2 0 0 2 2 2 1 Biotin-requiring enzyme ACR_tran PF00873.19 ACL96274.1 - 9.6e-293 973.7 15.9 1.3e-292 973.3 15.9 1.1 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family AsnC_trans_reg PF01037.21 ACL96274.1 - 0.066 13.2 0.0 0.25 11.4 0.0 2.0 1 0 0 1 1 1 0 Lrp/AsnC ligand binding domain DUF3592 PF12158.8 ACL96274.1 - 0.4 10.7 4.5 0.81 9.7 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3592) DUF190 PF02641.15 ACL96275.1 - 1.2e-28 99.3 0.0 1.3e-28 99.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, COG1993 E1-E2_ATPase PF00122.20 ACL96276.1 - 2.1e-49 167.5 0.5 2.1e-49 167.5 0.5 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 ACL96276.1 - 1.8e-39 136.2 1.5 3.4e-39 135.3 1.5 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ACL96276.1 - 0.00012 22.5 0.2 0.0024 18.3 0.2 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DAHP_snth_FXD PF18152.1 ACL96276.1 - 0.0071 16.2 0.0 0.023 14.5 0.0 1.9 1 0 0 1 1 1 1 DAHP synthase ferredoxin-like domain Hydrolase_3 PF08282.12 ACL96276.1 - 0.05 13.3 2.5 0.099 12.4 2.5 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Glutaredoxin PF00462.24 ACL96277.1 - 7.5e-08 32.5 0.0 1e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin HTH_Tnp_1 PF01527.20 ACL96278.1 - 4.6e-10 39.7 0.2 1e-09 38.6 0.2 1.7 1 1 0 1 1 1 1 Transposase HTH_28 PF13518.6 ACL96278.1 - 0.0029 17.7 0.1 0.0052 16.9 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Cas_Cas1 PF01867.16 ACL96278.1 - 0.099 11.8 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 CRISPR associated protein Cas1 COMP PF11598.8 ACL96278.1 - 0.28 11.7 2.2 0.32 11.5 0.8 1.9 2 1 0 2 2 2 0 Cartilage oligomeric matrix protein rve PF00665.26 ACL96279.1 - 9e-33 113.0 0.0 1.4e-32 112.3 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain HTH_32 PF13565.6 ACL96279.1 - 5.5e-16 58.9 0.7 1.9e-15 57.2 0.1 2.3 2 0 0 2 2 2 1 Homeodomain-like domain rve_3 PF13683.6 ACL96279.1 - 3.6e-15 55.5 0.5 6.9e-15 54.6 0.5 1.5 1 0 0 1 1 1 1 Integrase core domain HTH_28 PF13518.6 ACL96279.1 - 3e-10 40.1 0.8 1.4e-09 37.9 0.0 2.4 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_29 PF13551.6 ACL96279.1 - 3.1e-07 30.3 0.0 2.5e-06 27.4 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 ACL96279.1 - 5.1e-07 29.3 7.0 1.2e-06 28.2 0.0 3.7 4 0 0 4 4 4 1 Homeodomain-like domain HTH_Tnp_1 PF01527.20 ACL96279.1 - 4e-06 27.1 0.0 2e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 Transposase LZ_Tnp_IS481 PF13011.6 ACL96279.1 - 5.2e-06 26.9 0.0 1.2e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 leucine-zipper of insertion element IS481 DDE_Tnp_IS240 PF13610.6 ACL96279.1 - 0.00016 21.9 0.0 0.001 19.3 0.0 2.3 2 1 0 2 2 2 1 DDE domain CENP-B_N PF04218.13 ACL96279.1 - 0.008 15.8 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HU-CCDC81_bac_1 PF18174.1 ACL96279.1 - 0.0088 15.9 0.0 0.051 13.5 0.0 2.1 2 0 0 2 2 2 1 CCDC81-like prokaryotic HU domain 1 CAAP1 PF15335.6 ACL96280.1 - 2.6e-09 37.5 0.0 3.2 8.4 0.0 9.3 7 2 2 10 10 10 2 Caspase activity and apoptosis inhibitor 1 SAM_3 PF18016.1 ACL96280.1 - 0.0096 15.7 6.2 6.4 6.7 0.1 6.1 5 1 2 7 7 7 2 SAM domain (Sterile alpha motif) DUF4351 PF14261.6 ACL96280.1 - 0.055 13.5 47.1 9.5 6.4 0.2 15.0 7 6 8 15 15 15 0 Domain of unknown function (DUF4351) HTH_26 PF13443.6 ACL96280.1 - 0.067 13.6 18.3 20 5.7 0.1 9.2 8 5 2 10 10 10 0 Cro/C1-type HTH DNA-binding domain E1_FCCH PF16190.5 ACL96285.1 - 6.4e-12 45.5 0.0 2.7e-07 30.7 0.1 2.7 2 0 0 2 2 2 2 Ubiquitin-activating enzyme E1 FCCH domain Tad PF13400.6 ACL96285.1 - 2.7e-07 30.8 11.7 2.7e-07 30.8 11.7 2.7 2 1 0 2 2 2 1 Putative Flp pilus-assembly TadE/G-like VWA PF00092.28 ACL96285.1 - 0.00011 22.5 0.0 0.21 11.8 0.0 3.0 2 1 0 2 2 2 2 von Willebrand factor type A domain TadE PF07811.12 ACL96285.1 - 0.0002 21.6 2.5 0.00048 20.3 2.5 1.7 1 0 0 1 1 1 1 TadE-like protein VWA_2 PF13519.6 ACL96285.1 - 0.00074 20.1 0.1 0.047 14.4 0.0 3.4 3 1 0 3 3 3 1 von Willebrand factor type A domain TadF PF16964.5 ACL96285.1 - 0.12 12.2 0.1 0.4 10.4 0.0 1.9 2 0 0 2 2 2 0 Putative tight adherence pilin protein F HipA_C PF07804.12 ACL96286.1 - 5.2e-43 147.2 0.0 7.4e-43 146.7 0.0 1.2 1 0 0 1 1 1 1 HipA-like C-terminal domain Couple_hipA PF13657.6 ACL96286.1 - 1e-20 74.2 0.0 2.3e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 HipA N-terminal domain HTH_31 PF13560.6 ACL96287.1 - 1.2e-11 44.7 1.6 5.8e-11 42.6 1.6 2.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 ACL96287.1 - 5.1e-09 36.1 0.0 1.2e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 ACL96287.1 - 3.1e-07 30.3 0.0 6.4e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 ACL96287.1 - 0.003 17.4 0.0 0.0057 16.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 ACL96287.1 - 0.007 16.8 0.0 0.016 15.7 0.0 1.5 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_37 PF13744.6 ACL96287.1 - 0.037 14.0 0.0 0.092 12.7 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain MqsA_antitoxin PF15731.5 ACL96287.1 - 0.17 12.0 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA DDE_Tnp_IS240 PF13610.6 ACL96290.1 - 2.8e-18 66.5 0.1 3.5e-18 66.2 0.1 1.1 1 0 0 1 1 1 1 DDE domain rve PF00665.26 ACL96290.1 - 0.0034 17.5 0.0 0.0059 16.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain TPR_16 PF13432.6 ACL96290.1 - 0.041 14.5 2.8 0.041 14.5 2.8 2.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 ACL96290.1 - 0.1 13.3 0.3 0.32 11.7 0.3 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat GBR_NSP5 PF17580.2 ACL96290.1 - 0.23 11.3 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 Group B Rotavirus Non-structural protein 5 Transposase_20 PF02371.16 ACL96291.1 - 3.3e-26 91.4 0.4 8.1e-26 90.2 0.4 1.7 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family DEDD_Tnp_IS110 PF01548.17 ACL96291.1 - 1.5e-14 54.2 0.1 4.6e-14 52.6 0.0 1.8 2 0 0 2 2 2 1 Transposase Glyco_transf_4 PF13439.6 ACL96291.1 - 0.092 12.7 0.9 0.17 11.9 0.3 1.7 2 0 0 2 2 2 0 Glycosyltransferase Family 4 HTH_Tnp_1 PF01527.20 ACL96292.1 - 6.3e-22 77.7 0.3 7.5e-22 77.4 0.3 1.1 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 ACL96292.1 - 6.7e-05 22.9 0.1 0.00016 21.7 0.1 1.8 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 ACL96292.1 - 0.00034 20.3 0.1 0.00084 19.1 0.1 1.8 1 1 0 1 1 1 1 Homeodomain-like domain HTH_11 PF08279.12 ACL96292.1 - 0.0013 18.7 0.1 0.003 17.5 0.0 1.6 2 0 0 2 2 2 1 HTH domain HTH_29 PF13551.6 ACL96292.1 - 0.0045 17.0 0.1 0.013 15.5 0.1 2.0 1 1 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_1_2 PF13022.6 ACL96292.1 - 0.0058 16.8 0.1 0.013 15.7 0.1 1.6 1 1 0 1 1 1 1 Helix-turn-helix of insertion element transposase CENP-B_N PF04218.13 ACL96292.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_AsnC-type PF13404.6 ACL96292.1 - 0.02 14.7 0.1 0.09 12.6 0.0 2.1 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_psq PF05225.16 ACL96292.1 - 0.027 14.2 0.2 2.1 8.2 0.0 2.3 1 1 1 2 2 2 0 helix-turn-helix, Psq domain Terminase_5 PF06056.12 ACL96292.1 - 0.035 14.0 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) HTH_24 PF13412.6 ACL96292.1 - 0.047 13.3 2.3 0.19 11.3 0.0 2.7 3 1 1 4 4 4 0 Winged helix-turn-helix DNA-binding MerR PF00376.23 ACL96292.1 - 0.08 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 MerR family regulatory protein YdaS_antitoxin PF15943.5 ACL96292.1 - 0.1 12.5 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT MerR_1 PF13411.6 ACL96292.1 - 0.11 12.6 0.0 0.3 11.2 0.0 1.9 2 1 0 2 2 2 0 MerR HTH family regulatory protein rve_3 PF13683.6 ACL96293.1 - 4.2e-32 109.7 0.1 1e-31 108.5 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain rve PF00665.26 ACL96293.1 - 1.6e-23 83.2 0.0 2.8e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain HTH_21 PF13276.6 ACL96293.1 - 1.6e-09 37.7 6.5 3.8e-09 36.5 6.5 1.6 1 0 0 1 1 1 1 HTH-like domain rve_2 PF13333.6 ACL96293.1 - 0.0013 18.8 0.0 0.0026 17.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain HTH_32 PF13565.6 ACL96293.1 - 4.6 7.9 15.2 2.9 8.6 2.3 3.6 2 1 1 4 4 4 0 Homeodomain-like domain Peptidase_S8 PF00082.22 ACL96294.1 - 6e-22 78.3 0.2 8.3e-22 77.8 0.2 1.1 1 0 0 1 1 1 1 Subtilase family RadC PF04002.15 ACL96295.1 - 5.6e-19 68.3 0.0 5.9e-19 68.2 0.0 1.0 1 0 0 1 1 1 1 RadC-like JAB domain Prok-JAB PF14464.6 ACL96295.1 - 0.0027 17.5 0.1 0.003 17.3 0.1 1.0 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF2272 PF10030.9 ACL96296.1 - 9.8e-14 51.5 0.0 1.3e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2272) Peptidase_M19 PF01244.21 ACL96297.1 - 5.7e-97 324.7 0.0 7.1e-97 324.4 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Ferric_reduct PF01794.19 ACL96298.1 - 2.8e-17 63.0 6.7 1e-16 61.2 6.9 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component Oxidored_molyb PF00174.19 ACL96299.1 - 1.6e-27 96.2 0.0 2.3e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Metal_resist PF13801.6 ACL96300.1 - 1.3e-17 64.2 23.5 2.4e-14 53.6 19.7 2.2 1 1 1 2 2 2 2 Heavy-metal resistance LTXXQ PF07813.12 ACL96300.1 - 0.0028 18.3 5.1 0.0028 18.3 5.1 1.7 2 0 0 2 2 2 1 LTXXQ motif family protein DUF3106 PF11304.8 ACL96300.1 - 0.04 14.4 2.9 6.7 7.2 1.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3106) DUF2244 PF10003.9 ACL96300.1 - 0.11 12.2 0.9 5.7 6.6 0.1 2.4 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Phage_int_SAM_1 PF02899.17 ACL96300.1 - 0.17 12.2 1.2 0.32 11.3 1.2 1.3 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Sigma70_r2 PF04542.14 ACL96302.1 - 1.2e-21 76.2 3.1 2e-21 75.6 3.1 1.3 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 ACL96302.1 - 4.3e-10 39.1 1.0 8.8e-10 38.1 1.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 ACL96302.1 - 6.4e-05 22.4 0.2 0.00013 21.4 0.2 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 ACL96302.1 - 0.011 15.6 1.4 0.48 10.3 1.4 2.5 1 1 0 1 1 1 0 ECF sigma factor DUF134 PF02001.16 ACL96302.1 - 0.068 13.7 0.1 0.19 12.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF134 EF-hand_1 PF00036.32 ACL96303.1 - 6.3e-14 50.4 0.2 2e-05 23.8 0.1 3.2 2 1 1 3 3 3 3 EF hand EF-hand_5 PF13202.6 ACL96303.1 - 3e-12 45.4 0.6 3.2e-05 23.2 0.1 3.2 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 ACL96303.1 - 4.7e-12 46.2 2.1 9.8e-08 32.4 0.7 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 ACL96303.1 - 4.1e-11 41.9 0.2 0.0006 19.5 0.1 3.3 2 1 1 3 3 3 3 EF-hand domain SPARC_Ca_bdg PF10591.9 ACL96303.1 - 1.7e-05 25.1 0.3 0.13 12.6 0.1 2.8 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 ACL96303.1 - 6e-05 22.8 0.0 0.084 12.7 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain pair Dockerin_1 PF00404.18 ACL96303.1 - 0.028 14.6 2.2 8.8 6.6 0.0 3.0 2 1 0 2 2 2 0 Dockerin type I domain Excalibur PF05901.11 ACL96303.1 - 0.17 12.5 2.6 15 6.3 0.7 3.2 3 0 0 3 3 3 0 Excalibur calcium-binding domain GlnE PF03710.15 ACL96304.2 - 3.1e-146 485.4 0.1 2.9e-73 246.4 0.0 2.8 3 0 0 3 3 3 2 Glutamate-ammonia ligase adenylyltransferase GlnD_UR_UTase PF08335.11 ACL96304.2 - 5.3e-42 143.4 6.1 2.6e-32 111.9 0.6 2.8 3 0 0 3 3 3 2 GlnD PII-uridylyltransferase DUF294_C PF10335.9 ACL96304.2 - 3.1e-05 23.8 1.2 0.03 14.1 0.1 2.6 2 0 0 2 2 2 2 Putative nucleotidyltransferase substrate binding domain DUF294 PF03445.13 ACL96304.2 - 5.1e-05 23.1 0.0 0.0045 16.8 0.0 2.6 2 0 0 2 2 2 1 Putative nucleotidyltransferase DUF294 T2SSF PF00482.23 ACL96304.2 - 4.6 7.2 6.3 4 7.4 0.0 3.6 4 0 0 4 4 4 0 Type II secretion system (T2SS), protein F Peptidase_M56 PF05569.11 ACL96305.2 - 1e-62 212.0 5.8 4.9e-46 157.3 0.0 3.0 1 1 1 2 2 2 2 BlaR1 peptidase M56 HATPase_c PF02518.26 ACL96307.1 - 3e-19 69.6 0.0 1.6e-18 67.3 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 ACL96307.1 - 5.8e-10 39.4 1.3 5.8e-10 39.4 1.3 2.5 3 0 0 3 3 3 1 HAMP domain HisKA PF00512.25 ACL96307.1 - 0.00031 20.7 2.1 0.00072 19.5 0.1 2.5 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 ACL96307.1 - 0.059 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 ACL96307.1 - 0.061 13.3 0.0 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain Rrf2 PF02082.20 ACL96307.1 - 0.099 13.0 0.0 0.73 10.2 0.1 2.3 2 0 0 2 2 2 0 Transcriptional regulator HATPase_c_5 PF14501.6 ACL96307.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 GHKL domain ParE_toxin PF05016.15 ACL96308.1 - 2.2e-14 53.8 0.0 2.4e-14 53.7 0.0 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE Trans_reg_C PF00486.28 ACL96310.1 - 6.3e-28 96.7 0.0 1.1e-27 95.9 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal Response_reg PF00072.24 ACL96310.1 - 9.3e-27 93.4 0.0 1.8e-26 92.5 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Trypsin_2 PF13365.6 ACL96311.1 - 1.4e-32 113.7 0.3 2.7e-32 112.8 0.3 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 ACL96311.1 - 4.1e-27 94.3 6.2 3e-19 69.1 0.1 2.8 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 ACL96311.1 - 7.5e-16 57.7 7.6 1.2e-10 41.0 0.3 3.0 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 ACL96311.1 - 6.6e-15 55.2 4.8 4.3e-09 36.6 0.4 2.7 2 0 0 2 2 2 2 PDZ domain Trypsin PF00089.26 ACL96311.1 - 6.3e-13 49.0 0.1 1.3e-12 48.0 0.1 1.4 1 0 0 1 1 1 1 Trypsin Peptidase_S46 PF10459.9 ACL96311.1 - 0.0069 15.1 0.0 0.61 8.7 0.0 2.2 2 0 0 2 2 2 2 Peptidase S46 Tricorn_PDZ PF14685.6 ACL96311.1 - 0.017 15.0 0.9 0.75 9.8 0.1 2.6 2 0 0 2 2 2 0 Tricorn protease PDZ domain LSM PF01423.22 ACL96311.1 - 0.094 12.4 0.1 0.54 10.0 0.0 2.1 2 0 0 2 2 2 0 LSM domain CcmH PF03918.14 ACL96312.1 - 1.7e-50 170.1 0.1 2e-50 169.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome C biogenesis protein DUF4328 PF14219.6 ACL96312.1 - 0.026 14.1 0.4 0.055 13.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) CwsA PF10814.8 ACL96312.1 - 0.1 12.8 2.1 0.79 9.9 0.0 2.4 2 1 0 2 2 2 0 Cell wall synthesis protein CwsA DUF4148 PF13663.6 ACL96312.1 - 0.12 12.5 2.2 0.36 11.0 2.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4148) CcmF_C PF16327.5 ACL96313.1 - 3.1e-101 338.9 4.7 3.1e-101 338.9 4.7 1.7 2 0 0 2 2 2 1 Cytochrome c-type biogenesis protein CcmF C-terminal Cytochrom_C_asm PF01578.20 ACL96313.1 - 3.7e-46 157.6 16.9 3.7e-46 157.6 16.9 2.2 3 0 0 3 3 3 1 Cytochrome C assembly protein CcmE PF03100.15 ACL96314.1 - 1.2e-41 141.7 0.0 1.5e-41 141.4 0.0 1.0 1 0 0 1 1 1 1 CcmE TPR_19 PF14559.6 ACL96315.1 - 5.3e-09 36.5 19.9 4.3e-05 24.0 0.5 4.1 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 ACL96315.1 - 1.1e-06 28.2 0.3 0.012 15.3 0.0 3.2 3 0 0 3 3 3 2 TPR repeat TPR_14 PF13428.6 ACL96315.1 - 0.00016 22.2 2.6 0.00059 20.4 1.2 6.4 4 3 3 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 ACL96315.1 - 0.00066 19.9 0.0 23 5.6 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 ACL96315.1 - 0.017 15.7 1.1 0.017 15.7 1.1 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 ACL96315.1 - 0.018 15.1 1.8 0.3 11.3 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 ACL96315.1 - 0.034 14.4 0.2 0.57 10.5 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 ACL96315.1 - 0.64 10.8 5.1 6.1 7.7 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 ACL96315.1 - 1.6 8.9 13.3 0.13 12.4 0.6 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Abhydrolase_1 PF00561.20 ACL96316.2 - 6.1e-13 49.0 0.0 9.9e-11 41.8 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ACL96316.2 - 1.2e-11 45.7 3.7 1.7e-11 45.2 3.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ACL96316.2 - 8.4e-10 38.3 0.0 1.1e-08 34.6 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 ACL96316.2 - 3.8e-05 23.9 0.0 3.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_4 PF08386.10 ACL96316.2 - 7.3e-05 22.8 0.0 0.00013 22.1 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_3 PF07859.13 ACL96316.2 - 0.0018 18.1 0.1 0.018 14.9 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 ACL96316.2 - 0.0081 15.8 0.0 0.026 14.2 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Esterase PF00756.20 ACL96316.2 - 0.047 13.3 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Ndr PF03096.14 ACL96316.2 - 0.084 11.6 0.0 0.096 11.4 0.0 1.3 1 1 0 1 1 1 0 Ndr family LIDHydrolase PF10230.9 ACL96316.2 - 0.093 12.3 0.0 0.42 10.1 0.0 1.8 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 ACL96316.2 - 0.12 12.2 0.0 2.6 7.9 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase DUF1186 PF06685.11 ACL96317.1 - 0.021 14.2 0.0 0.18 11.2 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1186) PSI_PsaF PF02507.15 ACL96317.1 - 0.092 12.6 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III Radical_SAM_C PF16199.5 ACL96317.1 - 0.18 11.8 0.0 0.51 10.4 0.0 1.7 1 0 0 1 1 1 0 Radical_SAM C-terminal domain ABC_tran_Xtn PF12848.7 ACL96317.1 - 2.8 8.0 0.0 2.8 8.0 0.0 2.9 3 1 1 4 4 4 0 ABC transporter HATPase_c PF02518.26 ACL96318.1 - 1.9e-11 44.5 0.0 3.2e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 2CSK_N PF08521.10 ACL96318.1 - 4.4e-05 23.6 0.7 4.4e-05 23.6 0.7 2.1 2 0 0 2 2 2 1 Two-component sensor kinase N-terminal HATPase_c_2 PF13581.6 ACL96318.1 - 0.00019 21.4 0.0 0.00046 20.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HisKA PF00512.25 ACL96318.1 - 0.0029 17.6 1.1 0.014 15.4 1.1 2.2 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 ACL96318.1 - 0.0091 15.9 0.0 0.025 14.5 0.0 1.7 1 1 0 1 1 1 1 GHKL domain DUF883 PF05957.13 ACL96318.1 - 0.028 15.0 3.4 0.099 13.3 3.4 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 ACL96318.1 - 0.04 13.8 7.6 0.068 13.0 7.6 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain T2SSF PF00482.23 ACL96318.1 - 0.062 13.3 0.6 0.062 13.3 0.6 3.0 3 1 0 3 3 3 0 Type II secretion system (T2SS), protein F HPTransfase PF10090.9 ACL96318.1 - 0.083 12.7 0.0 0.22 11.3 0.0 1.8 1 0 0 1 1 1 0 Histidine phosphotransferase C-terminal domain Sensor_TM1 PF13755.6 ACL96318.1 - 0.12 12.2 2.2 0.35 10.6 2.2 1.7 1 1 0 1 1 1 0 Sensor N-terminal transmembrane domain DUF948 PF06103.11 ACL96318.1 - 0.16 12.3 3.0 0.35 11.2 0.0 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Herpes_BLRF2 PF05812.12 ACL96318.1 - 0.21 11.8 1.2 0.63 10.2 1.2 1.8 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein SlyX PF04102.12 ACL96318.1 - 1.2 9.8 5.7 12 6.6 0.3 2.7 1 1 1 2 2 2 0 SlyX Response_reg PF00072.24 ACL96319.1 - 5.7e-26 90.9 0.0 7.7e-26 90.5 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 ACL96319.1 - 2.6e-23 81.9 0.3 2.6e-23 81.9 0.3 1.7 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal PepSY_2 PF13670.6 ACL96320.1 - 1.5e-05 24.9 1.2 0.0018 18.2 1.2 2.0 1 1 0 1 1 1 1 Peptidase propeptide and YPEB domain PepSY PF03413.19 ACL96320.1 - 0.0027 18.2 0.0 0.0089 16.6 0.0 1.9 2 1 0 2 2 2 1 Peptidase propeptide and YPEB domain ODV-E18 PF10717.9 ACL96321.1 - 0.41 10.5 0.2 0.41 10.5 0.2 1.6 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 HipA_C PF07804.12 ACL96323.1 - 8.5e-47 159.6 0.0 1.2e-46 159.1 0.0 1.1 1 0 0 1 1 1 1 HipA-like C-terminal domain Couple_hipA PF13657.6 ACL96323.1 - 2.8e-22 79.2 0.0 8e-22 77.8 0.0 1.8 1 0 0 1 1 1 1 HipA N-terminal domain HTH_3 PF01381.22 ACL96324.1 - 5.1e-08 32.8 0.4 8.7e-08 32.1 0.4 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 ACL96324.1 - 2e-07 31.2 9.6 2e-07 31.2 9.6 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_25 PF13413.6 ACL96324.1 - 1.6e-06 27.9 1.3 2.5e-06 27.2 1.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 ACL96324.1 - 0.00038 20.4 0.1 0.00059 19.8 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 ACL96324.1 - 0.0021 17.5 0.5 0.0021 17.5 0.5 2.0 3 0 0 3 3 3 1 Sigma-70, region 4 HTH_37 PF13744.6 ACL96324.1 - 0.0025 17.7 0.8 0.0046 16.9 0.8 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 ACL96324.1 - 0.0025 17.6 2.3 0.0025 17.6 2.3 2.0 2 1 0 2 2 2 1 Homeodomain-like domain HTH_Crp_2 PF13545.6 ACL96324.1 - 0.0089 16.0 0.4 0.02 14.9 0.4 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_26 PF13443.6 ACL96324.1 - 0.011 16.1 0.2 0.017 15.5 0.2 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 ACL96324.1 - 0.015 14.8 0.4 0.057 13.0 0.1 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding MqsA_antitoxin PF15731.5 ACL96324.1 - 0.019 15.1 0.1 0.025 14.7 0.1 1.1 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA HTH_Tnp_ISL3 PF13542.6 ACL96324.1 - 0.025 14.0 0.3 0.046 13.1 0.3 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.12 ACL96324.1 - 0.078 12.9 0.3 0.16 11.9 0.3 1.5 1 0 0 1 1 1 0 HTH domain HTH_28 PF13518.6 ACL96324.1 - 0.11 12.6 2.0 0.27 11.4 0.2 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain LacI PF00356.21 ACL96324.1 - 0.14 12.0 0.5 0.34 10.7 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family LZ_Tnp_IS481 PF13011.6 ACL96324.1 - 0.27 11.8 5.3 0.12 12.9 1.5 2.2 2 1 0 2 2 2 0 leucine-zipper of insertion element IS481 DnaJ_C PF01556.18 ACL96325.1 - 3.9e-33 114.6 0.0 5.1e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ACL96325.1 - 1.5e-23 82.6 0.3 2.7e-23 81.8 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain DUF222 PF02720.17 ACL96325.1 - 0.15 11.5 0.1 0.31 10.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF222) GTA_TIM PF13547.6 ACL96326.1 - 8.4e-137 455.4 0.1 1.1e-136 455.0 0.1 1.1 1 0 0 1 1 1 1 GTA TIM-barrel-like domain Phage-tail_3 PF13550.6 ACL96326.1 - 3.9e-28 98.3 10.2 3.9e-28 98.3 10.2 2.0 2 0 0 2 2 2 1 Putative phage tail protein NLPC_P60 PF00877.19 ACL96328.3 - 2.3e-06 27.6 0.0 6.9e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 NlpC/P60 family DUF2163 PF09931.9 ACL96329.1 - 4.3e-46 157.1 0.1 4.9e-46 156.9 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2163) Phage_BR0599 PF09356.10 ACL96329.1 - 1.6e-09 38.0 0.8 8.6e-09 35.6 0.5 2.1 2 0 0 2 2 2 1 Phage conserved hypothetical protein BR0599 DUF2460 PF09343.10 ACL96330.1 - 1.3e-76 256.6 0.0 1.4e-76 256.4 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein 2217 (DUF2460) DUF805 PF05656.14 ACL96331.2 - 4e-14 52.9 9.5 9.9e-14 51.6 9.5 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF805) TctB PF07331.11 ACL96331.2 - 0.0024 18.1 13.2 0.0037 17.6 13.2 1.2 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family TrbC PF04956.13 ACL96331.2 - 0.019 15.2 0.8 0.019 15.2 0.8 2.3 1 1 1 2 2 2 0 TrbC/VIRB2 family CPP1-like PF11833.8 ACL96331.2 - 0.81 9.3 7.1 1 9.0 6.9 1.3 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like RDD PF06271.12 ACL96331.2 - 4.8 7.4 13.4 0.78 9.9 4.9 2.1 1 1 0 2 2 2 0 RDD family Tape_meas_lam_C PF09718.10 ACL96332.1 - 0.011 15.8 0.9 0.011 15.8 0.9 1.7 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Phage_TAC_6 PF09550.10 ACL96333.1 - 6.6e-16 58.5 5.9 7.3e-16 58.3 5.9 1.0 1 0 0 1 1 1 1 Phage tail assembly chaperone protein, TAC Phage_TAC_11 PF11836.8 ACL96334.1 - 2.8e-10 40.2 6.2 3.2e-10 40.0 6.2 1.1 1 0 0 1 1 1 1 Phage tail tube protein, GTA-gp10 Phage_tail_2 PF06199.11 ACL96335.1 - 1.2e-43 148.5 0.0 1.3e-43 148.4 0.0 1.0 1 0 0 1 1 1 1 Phage tail tube protein DUF3168 PF11367.8 ACL96336.2 - 2.7e-27 95.3 2.3 3.1e-27 95.1 2.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3168) Phage_capsid PF05065.13 ACL96337.1 - 3.6e-89 298.8 0.2 5.4e-89 298.2 0.2 1.2 1 0 0 1 1 1 1 Phage capsid family DUF16 PF01519.16 ACL96337.1 - 0.23 12.0 0.0 0.45 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 Peptidase_S78 PF04586.17 ACL96339.1 - 1.1e-26 93.9 0.0 1.5e-26 93.6 0.0 1.0 1 0 0 1 1 1 1 Caudovirus prohead serine protease Cupin_7 PF12973.7 ACL96339.1 - 0.016 15.1 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 ChrR Cupin-like domain Phage_portal PF04860.12 ACL96341.1 - 2.5e-78 263.4 0.0 2.9e-78 263.2 0.0 1.0 1 0 0 1 1 1 1 Phage portal protein DUF559 PF04480.12 ACL96342.1 - 4.3e-28 97.3 0.0 5e-28 97.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF559) MTES_1575 PF18741.1 ACL96342.1 - 8.2e-06 25.9 0.0 9.9e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 REase_MTES_1575 Terminase_6 PF03237.15 ACL96345.3 - 1.3e-35 123.0 0.0 2.5e-35 122.1 0.0 1.5 2 0 0 2 2 2 1 Terminase-like family Terminase_6C PF17289.2 ACL96345.3 - 3.9e-25 88.8 0.0 5.3e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 Terminase RNaseH-like domain DUF3094 PF11293.8 ACL96345.3 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) Aldedh PF00171.22 ACL96346.1 - 9.6e-43 146.3 0.0 1.3e-42 145.9 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cytochrome_CBB3 PF13442.6 ACL96347.1 - 8.3e-12 45.3 0.3 1.2e-11 44.8 0.3 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 ACL96347.1 - 4e-06 27.9 1.3 0.00065 20.8 1.3 2.2 1 1 0 1 1 1 1 Cytochrome c Amino_oxidase PF01593.24 ACL96348.1 - 2.6e-53 181.9 0.1 3.6e-53 181.5 0.1 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ACL96348.1 - 8.9e-10 38.7 0.1 3.6e-09 36.7 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ACL96348.1 - 1.6e-05 24.2 0.1 2.9e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 ACL96348.1 - 5.7e-05 22.5 0.1 0.00013 21.3 0.1 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 ACL96348.1 - 7e-05 21.7 0.5 0.00011 21.0 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 ACL96348.1 - 7.6e-05 22.1 0.2 0.00029 20.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ACL96348.1 - 0.0006 20.3 0.1 0.032 14.8 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ACL96348.1 - 0.00086 18.7 0.1 0.0032 16.8 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 ACL96348.1 - 0.001 18.2 0.1 0.0016 17.6 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 ACL96348.1 - 0.0028 17.0 0.0 0.0058 15.9 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 ACL96348.1 - 0.0028 17.3 0.1 0.0058 16.3 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ACL96348.1 - 0.006 16.0 0.1 0.01 15.2 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ACL96348.1 - 0.014 14.5 0.0 0.056 12.5 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 ACL96348.1 - 0.077 12.2 0.6 0.33 10.2 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 ACL96348.1 - 0.14 11.6 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus TetR_C_3 PF08362.11 ACL96349.1 - 4.5e-55 185.5 0.0 5.6e-55 185.2 0.0 1.1 1 0 0 1 1 1 1 YcdC-like protein, C-terminal region TetR_N PF00440.23 ACL96349.1 - 1.1e-14 53.9 0.1 2.7e-14 52.7 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_29 PF17938.1 ACL96349.1 - 1.1e-05 25.5 0.0 1.5e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain HTH_23 PF13384.6 ACL96349.1 - 0.008 15.9 0.2 0.021 14.6 0.2 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_20 PF12840.7 ACL96349.1 - 0.02 15.0 0.1 0.074 13.1 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain TetR_C_15 PF17918.1 ACL96349.1 - 0.23 12.2 5.6 0.19 12.5 1.7 2.6 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Isochorismatase PF00857.20 ACL96350.1 - 1.3e-39 136.2 0.0 1.7e-39 135.8 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Ribonuc_L-PSP PF01042.21 ACL96351.1 - 3.3e-30 104.6 0.0 3.9e-30 104.4 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP SLBB PF10531.9 ACL96351.1 - 0.044 13.6 0.1 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 SLBB domain Abhydrolase_1 PF00561.20 ACL96352.1 - 2.1e-25 89.8 0.2 1.9e-22 80.1 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ACL96352.1 - 6.3e-17 61.6 0.4 8.4e-17 61.2 0.4 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ACL96352.1 - 1.6e-11 45.2 11.6 2e-11 44.9 11.6 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 ACL96352.1 - 6e-06 25.2 0.0 1.2e-05 24.2 0.0 1.4 2 0 0 2 2 2 1 Ndr family Abhydrolase_4 PF08386.10 ACL96352.1 - 0.13 12.4 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein Bac_luciferase PF00296.20 ACL96353.1 - 1.1e-67 228.7 0.5 1.4e-67 228.4 0.5 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase FKBP_C PF00254.28 ACL96354.1 - 4.9e-22 78.1 0.0 6.7e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.18 ACL96354.1 - 4.4e-08 34.0 0.0 5.8e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF5597 PF18120.1 ACL96356.3 - 1.3e-32 112.7 0.1 2.9e-32 111.6 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5597) Glyco_hydro_42 PF02449.15 ACL96356.3 - 4.1e-11 42.8 0.1 6.2e-11 42.3 0.1 1.1 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_35 PF01301.19 ACL96356.3 - 2.8e-05 23.9 0.0 0.00019 21.1 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_43 PF04616.14 ACL96358.1 - 7.1e-102 340.6 0.2 1e-101 340.1 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 ACL96358.1 - 1.5e-37 129.3 0.0 2.1e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain DUF1349 PF07081.11 ACL96358.1 - 0.019 14.7 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1349) Glyco_hydro_10 PF00331.20 ACL96359.1 - 1.6e-88 296.9 0.0 1.9e-88 296.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Cellulase PF00150.18 ACL96359.1 - 0.013 14.9 0.0 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) TAT_signal PF10518.9 ACL96359.1 - 0.017 15.0 4.9 0.017 15.0 4.9 2.5 4 0 0 4 4 4 0 TAT (twin-arginine translocation) pathway signal sequence E3_binding PF02817.17 ACL96359.1 - 0.067 13.5 0.5 0.25 11.7 0.5 2.0 1 0 0 1 1 1 0 e3 binding domain TonB_dep_Rec PF00593.24 ACL96360.1 - 5.4e-28 99.1 30.8 5.4e-28 99.1 30.8 2.4 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 ACL96360.1 - 3.1e-09 37.4 0.5 3.1e-09 37.4 0.5 2.7 2 1 1 3 3 3 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 ACL96360.1 - 8.4e-05 21.7 4.9 8.4e-05 21.7 4.9 3.4 3 1 1 4 4 4 1 Outer membrane protein beta-barrel family Trp_halogenase PF04820.14 ACL96361.1 - 8e-196 651.3 0.0 9.3e-196 651.1 0.0 1.0 1 0 0 1 1 1 1 Tryptophan halogenase DAO PF01266.24 ACL96361.1 - 7.4e-06 25.8 0.4 1.5e-05 24.8 0.4 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ACL96361.1 - 0.0014 18.0 0.5 0.58 9.3 0.7 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ACL96361.1 - 0.0048 16.9 0.1 1.1 9.2 0.3 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 ACL96361.1 - 0.0068 15.5 0.3 0.21 10.6 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.7 ACL96361.1 - 0.0081 15.6 0.3 0.35 10.1 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 ACL96362.1 - 1.5e-72 244.9 0.0 1.1e-40 139.8 0.0 3.0 1 1 1 2 2 2 2 Tryptophan halogenase DUF1590 PF07629.11 ACL96362.1 - 0.027 14.3 0.2 0.027 14.3 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1590) NAD_binding_8 PF13450.6 ACL96362.1 - 0.046 13.9 0.2 0.1 12.8 0.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 ACL96363.1 - 9.5e-196 651.0 0.0 1.1e-195 650.8 0.0 1.0 1 0 0 1 1 1 1 Tryptophan halogenase DAO PF01266.24 ACL96363.1 - 1.8e-09 37.6 1.1 5.7e-09 36.0 1.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ACL96363.1 - 1.3e-05 24.6 0.7 0.013 14.8 0.3 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ACL96363.1 - 1.3e-05 24.4 0.1 0.17 10.9 0.3 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_oxidored PF12831.7 ACL96363.1 - 3.6e-05 23.3 0.2 0.13 11.6 0.6 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ACL96363.1 - 4e-05 23.7 0.1 0.014 15.4 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 ACL96363.1 - 0.0023 17.2 0.6 0.037 13.3 0.7 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 ACL96363.1 - 0.0045 17.2 0.7 0.01 16.1 0.7 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain PriA_3primeBD PF17764.1 ACL96363.1 - 0.0049 16.7 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 3′ DNA-binding domain (3′BD) FAD_binding_2 PF00890.24 ACL96363.1 - 0.015 14.4 2.7 0.025 13.7 2.7 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 ACL96363.1 - 0.045 12.5 0.3 0.065 11.9 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 ACL96363.1 - 0.1 11.7 1.1 1.1 8.2 2.3 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.27 ACL96363.1 - 0.13 12.9 0.2 1.7 9.2 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ACL96363.1 - 0.19 10.9 0.4 0.34 10.1 0.4 1.3 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 ACL96364.1 - 1.5e-197 657.0 0.0 1.7e-197 656.8 0.0 1.0 1 0 0 1 1 1 1 Tryptophan halogenase DAO PF01266.24 ACL96364.1 - 2.5e-05 24.0 1.3 0.00011 22.0 1.3 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ACL96364.1 - 0.00011 21.5 0.2 0.096 11.9 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ACL96364.1 - 0.00029 20.3 0.1 0.046 13.1 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 ACL96364.1 - 0.0079 16.7 0.3 0.089 13.4 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ACL96364.1 - 0.0096 16.1 0.7 0.04 14.1 0.7 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ACL96364.1 - 0.011 15.7 0.2 0.13 12.3 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 ACL96364.1 - 0.032 13.3 0.1 0.26 10.3 0.0 2.2 3 0 0 3 3 3 0 Lycopene cyclase protein Peptidase_M20 PF01546.28 ACL96365.2 - 9.1e-19 68.0 0.4 1.3e-18 67.4 0.4 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ACL96365.2 - 9.1e-12 44.9 0.0 2.2e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF4148 PF13663.6 ACL96365.2 - 0.06 13.5 0.9 3.7 7.8 0.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) MCPsignal PF00015.21 ACL96366.1 - 5.7e-19 68.6 15.6 7.5e-18 64.9 13.1 2.8 2 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain PAS_9 PF13426.7 ACL96366.1 - 5.7e-11 42.6 0.0 1e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 ACL96366.1 - 7.5e-10 39.0 0.0 2.4e-09 37.4 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 ACL96366.1 - 2.3e-07 31.0 0.0 7.5e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 ACL96366.1 - 3.7e-07 30.1 0.0 8.1e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 ACL96366.1 - 0.069 13.2 0.0 0.25 11.4 0.0 2.0 1 0 0 1 1 1 0 PAS domain Glyco_hydro_67M PF07488.12 ACL96367.1 - 6e-153 508.6 0.0 7.6e-153 508.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.12 ACL96367.1 - 2.6e-86 288.8 0.6 4.4e-86 288.0 0.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.14 ACL96367.1 - 4.1e-25 88.4 0.0 6.3e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus DUF4838 PF16126.5 ACL96367.1 - 0.0062 16.0 0.0 0.016 14.6 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4838) MR_MLE_C PF13378.6 ACL96368.1 - 5.7e-44 150.3 0.0 1e-43 149.5 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 ACL96368.1 - 1.7e-31 108.9 0.0 3.5e-31 107.8 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain FCD PF07729.12 ACL96369.1 - 6e-26 91.3 14.2 6e-26 91.3 14.2 1.8 2 0 0 2 2 2 1 FCD domain GntR PF00392.21 ACL96369.1 - 1.7e-22 78.8 0.1 3.9e-22 77.7 0.1 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_11 PF08279.12 ACL96369.1 - 0.00063 19.6 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 HTH domain HTH_41 PF14502.6 ACL96369.1 - 0.0012 18.5 0.0 0.0024 17.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 ACL96369.1 - 0.0056 16.6 2.8 0.01 15.8 0.0 2.6 3 0 0 3 3 3 1 Crp-like helix-turn-helix domain HTH_IclR PF09339.10 ACL96369.1 - 0.006 16.4 0.8 0.02 14.7 0.1 2.3 2 0 0 2 2 2 1 IclR helix-turn-helix domain PHBC_N PF12551.8 ACL96369.1 - 0.0083 15.9 0.3 0.078 12.8 0.1 2.5 2 0 0 2 2 2 1 Poly-beta-hydroxybutyrate polymerase N terminal Rrf2 PF02082.20 ACL96369.1 - 0.014 15.7 0.0 0.05 13.9 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator TrmB PF01978.19 ACL96369.1 - 0.019 14.9 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_10 PF04967.12 ACL96369.1 - 0.026 14.3 0.0 0.31 10.9 0.0 2.6 2 0 0 2 2 2 0 HTH DNA binding domain Polyoma_coat2 PF00761.20 ACL96369.1 - 0.032 13.9 0.0 0.067 12.9 0.0 1.5 1 1 0 1 1 1 0 Polyomavirus coat protein HTH_24 PF13412.6 ACL96369.1 - 0.055 13.0 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DprA_WH PF17782.1 ACL96369.1 - 0.078 13.1 1.6 0.39 10.9 0.2 2.7 2 1 1 3 3 3 0 DprA winged helix domain HTH_DeoR PF08220.12 ACL96369.1 - 0.08 12.7 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain MarR PF01047.22 ACL96369.1 - 0.094 12.7 0.1 0.51 10.3 0.0 2.2 3 0 0 3 3 3 0 MarR family RepL PF05732.11 ACL96369.1 - 0.15 11.5 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) GP67 PF17634.2 ACL96369.1 - 0.74 10.3 4.8 1.3 9.5 1.9 2.3 2 0 0 2 2 2 0 Gene product 67 DUF559 PF04480.12 ACL96370.1 - 8.9e-47 157.5 0.3 1e-46 157.3 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF559) MTES_1575 PF18741.1 ACL96370.1 - 4.9e-10 39.4 0.4 1.6e-09 37.8 0.0 1.8 1 1 1 2 2 2 1 REase_MTES_1575 Acyl_transf_3 PF01757.22 ACL96371.1 - 5.9e-22 78.2 40.2 8.7e-22 77.6 40.2 1.3 1 1 0 1 1 1 1 Acyltransferase family DEDD_Tnp_IS110 PF01548.17 ACL96372.1 - 4.3e-20 72.1 0.0 8e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Transposase Transposase_20 PF02371.16 ACL96372.1 - 8e-18 64.5 0.2 1.9e-17 63.3 0.2 1.7 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family AP_endonuc_2 PF01261.24 ACL96372.1 - 0.098 12.1 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel HAD_2 PF13419.6 ACL96373.2 - 7.7e-07 29.4 0.0 9.1e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ACL96373.2 - 2e-06 28.2 0.0 2.7e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ACL96373.2 - 0.016 15.3 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like 2OG-FeII_Oxy_5 PF13759.6 ACL96374.2 - 6.5e-19 68.2 0.0 1.2e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase TPR_14 PF13428.6 ACL96374.2 - 3.2e-14 52.4 46.6 2.8e-05 24.6 0.7 7.7 3 2 5 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 ACL96374.2 - 8e-11 42.4 51.8 2.5e-07 31.2 6.4 5.8 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 ACL96374.2 - 3.7e-10 40.2 32.8 0.0029 18.1 0.3 5.1 2 1 2 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 ACL96374.2 - 1.1e-07 31.3 0.0 0.025 14.4 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 ACL96374.2 - 6.1e-07 29.4 3.6 0.024 15.0 0.0 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 ACL96374.2 - 1.1e-06 28.3 4.9 0.43 10.7 0.0 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 ACL96374.2 - 1.4e-06 28.1 0.0 0.35 11.2 0.0 5.5 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 ACL96374.2 - 8.2e-06 25.6 9.6 0.02 15.0 0.0 7.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 ACL96374.2 - 6e-05 23.3 1.1 6e-05 23.3 1.1 5.1 5 3 1 6 6 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 ACL96374.2 - 0.00022 20.6 17.7 0.0012 18.2 1.3 2.9 1 1 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ACL96374.2 - 0.00099 19.3 0.8 3 8.2 0.0 3.4 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 ACL96374.2 - 0.002 17.8 4.3 0.008 15.8 0.0 3.6 3 1 1 4 4 4 1 TPR repeat TPR_6 PF13174.6 ACL96374.2 - 0.0024 18.4 6.7 18 6.3 0.0 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat 2OG-FeII_Oxy_3 PF13640.6 ACL96374.2 - 0.0039 18.1 0.0 0.0077 17.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_10 PF13374.6 ACL96374.2 - 0.0048 16.7 23.2 2.8 7.9 0.6 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_4 PF07721.14 ACL96374.2 - 0.0077 16.8 47.5 3.4 8.6 1.6 8.5 8 0 0 8 8 7 3 Tetratricopeptide repeat NARP1 PF12569.8 ACL96374.2 - 0.14 11.0 0.2 0.67 8.8 0.0 1.9 2 1 1 3 3 3 0 NMDA receptor-regulated protein 1 ChAPs PF09295.10 ACL96374.2 - 0.35 9.8 0.2 0.84 8.6 0.0 1.7 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.6 ACL96374.2 - 0.96 9.8 16.5 2.5 8.5 0.4 5.2 3 1 3 6 6 5 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 ACL96374.2 - 1.1 9.2 10.8 3.7 7.4 0.1 3.4 3 1 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal TonB_dep_Rec PF00593.24 ACL96375.1 - 1e-43 150.9 30.4 1e-43 150.9 30.4 2.2 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 ACL96375.1 - 2.2e-23 82.9 4.6 7.3e-23 81.2 4.6 2.0 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 ACL96375.1 - 0.0087 15.1 0.3 0.0087 15.1 0.3 3.5 6 0 0 6 6 6 2 Outer membrane protein beta-barrel family 2OG-FeII_Oxy_4 PF13661.6 ACL96377.1 - 2.3e-28 98.7 0.0 3.4e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 ACL96377.1 - 7.6e-12 46.0 0.0 1.1e-11 45.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ofd1_CTDD PF10637.9 ACL96377.1 - 0.0029 17.0 0.0 0.0061 15.9 0.0 1.4 1 1 0 1 1 1 1 Oxoglutarate and iron-dependent oxygenase degradation C-term VasI PF11319.8 ACL96378.1 - 0.00044 20.0 0.1 0.0024 17.6 0.0 1.9 2 0 0 2 2 2 1 Type VI secretion system VasI, EvfG, VC_A0118 DUF4256 PF14066.6 ACL96378.1 - 0.048 13.3 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4256) PmbA_TldD PF01523.16 ACL96379.1 - 3e-57 194.6 0.1 4.7e-57 194.0 0.1 1.3 1 0 0 1 1 1 1 Putative modulator of DNA gyrase PmbA_TldD PF01523.16 ACL96380.1 - 2.9e-51 175.0 0.6 3.6e-51 174.6 0.6 1.1 1 0 0 1 1 1 1 Putative modulator of DNA gyrase DUF4159 PF13709.6 ACL96381.1 - 9.9e-52 175.3 0.0 1.1e-51 175.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4159) AAA_3 PF07726.11 ACL96382.1 - 1.2e-63 212.8 0.0 2e-63 212.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 ACL96382.1 - 2.8e-15 55.9 5.3 7.1e-15 54.6 5.3 1.7 1 0 0 1 1 1 1 AAA lid domain AAA_5 PF07728.14 ACL96382.1 - 4.7e-09 36.4 0.0 8.3e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 ACL96382.1 - 9.6e-05 22.2 0.0 0.00036 20.3 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 ACL96382.1 - 0.00035 21.0 0.0 0.0014 19.0 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MCM PF00493.23 ACL96382.1 - 0.00093 18.4 0.0 0.0058 15.7 0.0 2.0 1 1 0 1 1 1 1 MCM P-loop domain RuvB_N PF05496.12 ACL96382.1 - 0.0026 17.5 0.0 0.032 14.0 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ACL96382.1 - 0.0036 17.7 0.8 0.0068 16.8 0.1 1.9 2 1 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 ACL96382.1 - 0.0054 16.1 0.2 0.014 14.8 0.1 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 ACL96382.1 - 0.022 15.1 0.7 0.083 13.2 0.1 2.3 3 1 0 3 3 3 0 AAA domain AAA_25 PF13481.6 ACL96382.1 - 0.046 13.3 0.4 0.81 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ACL96382.1 - 0.14 12.1 0.2 0.38 10.6 0.0 1.7 2 0 0 2 2 2 0 NACHT domain DUF58 PF01882.18 ACL96383.1 - 1.1e-17 64.1 1.6 1.9e-17 63.3 0.9 1.8 2 0 0 2 2 2 1 Protein of unknown function DUF58 VWA_2 PF13519.6 ACL96383.1 - 1.4e-08 35.3 0.0 2.7e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain SpoIIE PF07228.12 ACL96383.1 - 0.019 14.9 0.0 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) BatA PF07584.11 ACL96384.1 - 2.2e-09 37.5 11.5 2.2e-09 37.5 11.5 2.3 2 0 0 2 2 2 1 Aerotolerance regulator N-terminal DUF4175 PF13779.6 ACL96385.1 - 1.8e-11 42.7 25.3 8.2e-09 34.0 15.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4175) ThuA PF06283.11 ACL96386.1 - 0.038 14.2 0.0 0.07 13.3 0.0 1.5 2 0 0 2 2 2 0 Trehalose utilisation HyaE PF07449.11 ACL96386.1 - 0.065 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE TonB_dep_Rec PF00593.24 ACL96388.1 - 1.3e-27 97.9 50.5 1.3e-27 97.9 50.5 3.0 1 1 2 3 3 3 1 TonB dependent receptor Plug PF07715.15 ACL96388.1 - 4.6e-15 56.1 8.4 1e-14 55.0 1.0 3.5 3 0 0 3 3 3 2 TonB-dependent Receptor Plug Domain DUF1272 PF06906.11 ACL96389.1 - 5.9e-27 93.5 9.1 7.5e-27 93.2 9.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) zf-RING_5 PF14634.6 ACL96389.1 - 0.72 9.9 9.1 1.2 9.1 9.1 1.4 1 1 0 1 1 1 0 zinc-RING finger domain CPSase_sm_chain PF00988.22 ACL96390.1 - 4.6e-45 152.6 0.0 7.2e-45 151.9 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 ACL96390.1 - 1.8e-43 148.6 0.0 2.3e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ACL96390.1 - 1e-06 28.7 2.9 0.00013 21.8 2.9 3.1 1 1 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.14 ACL96390.1 - 0.012 15.2 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 ACL96390.1 - 0.033 14.0 0.1 0.064 13.0 0.1 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family adh_short_C2 PF13561.6 ACL96392.1 - 1.3e-52 178.7 0.2 1.6e-52 178.4 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ACL96392.1 - 3.2e-37 127.9 0.0 3.9e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ACL96392.1 - 0.00018 21.5 0.1 0.00035 20.5 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ACL96392.1 - 0.02 14.3 0.0 0.032 13.7 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 ACL96392.1 - 0.084 12.2 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.8 ACL96392.1 - 0.12 12.1 0.3 0.12 12.1 0.3 1.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ADH_N PF08240.12 ACL96394.1 - 9.2e-28 96.3 6.1 1.4e-27 95.7 6.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ACL96394.1 - 6e-19 68.3 0.0 9.9e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ACL96394.1 - 2.3e-10 41.7 0.0 4e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ACL96394.1 - 2.7e-08 33.6 0.1 4.3e-08 32.9 0.1 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N_assoc PF13823.6 ACL96394.1 - 1.8e-06 27.7 0.0 4.4e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated AlaDh_PNT_C PF01262.21 ACL96394.1 - 0.002 17.5 1.1 0.0029 16.9 1.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ACL96394.1 - 0.034 13.5 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF559 PF04480.12 ACL96395.1 - 3.9e-42 142.5 0.2 4.8e-42 142.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF559) MTES_1575 PF18741.1 ACL96395.1 - 1.2e-06 28.6 0.0 1.7e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 REase_MTES_1575 Flg_bbr_C PF06429.13 ACL96396.1 - 5.1e-05 23.3 1.1 6.1e-05 23.1 1.1 1.2 1 0 0 1 1 1 1 Flagellar basal body rod FlgEFG protein C-terminal Peptidase_M28 PF04389.17 ACL96398.1 - 1.6e-46 158.5 0.0 2.8e-46 157.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ACL96398.1 - 5.7e-07 29.5 0.3 2e-06 27.7 0.3 2.0 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 ACL96398.1 - 6.3e-07 29.3 0.1 2.6e-06 27.3 0.1 2.1 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 ACL96398.1 - 0.00058 19.0 0.2 0.011 14.8 0.0 2.1 1 1 1 2 2 2 1 M42 glutamyl aminopeptidase Phage_holin_3_5 PF16085.5 ACL96398.1 - 0.0017 18.4 0.4 0.0041 17.2 0.4 1.6 1 0 0 1 1 1 1 Bacteriophage holin Hol, superfamily III CRA_rpt PF07046.11 ACL96398.1 - 0.42 10.8 3.8 1.2 9.4 0.2 2.6 2 0 0 2 2 2 0 Cytoplasmic repetitive antigen (CRA) like repeat DUF998 PF06197.13 ACL96399.1 - 2.2e-20 73.0 27.1 2.7e-20 72.7 27.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF998) MCPsignal PF00015.21 ACL96400.2 - 1.2e-44 152.1 21.8 2.8e-44 151.0 12.8 3.1 4 0 0 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain dCache_1 PF02743.18 ACL96400.2 - 2.3e-17 63.6 0.0 5e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 Cache domain HAMP PF00672.25 ACL96400.2 - 3.5e-05 24.1 11.8 0.0001 22.6 1.4 4.7 3 1 0 3 3 3 2 HAMP domain Syntaxin-6_N PF09177.11 ACL96400.2 - 0.088 13.4 0.7 1.9 9.1 0.0 2.8 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF2408 PF10303.9 ACL96400.2 - 0.15 12.6 0.0 4.3 7.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) GST_N PF02798.20 ACL96401.1 - 6.9e-17 61.6 0.0 1.1e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ACL96401.1 - 1.8e-13 50.7 0.0 3e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ACL96401.1 - 7.8e-11 42.1 0.0 1.7e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ACL96401.1 - 1.6e-09 37.8 0.0 2.2e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ACL96401.1 - 1.9e-07 31.2 0.0 3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ACL96401.1 - 3.7e-05 23.7 0.2 8.6e-05 22.5 0.2 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain alpha-hel2 PF14456.6 ACL96401.1 - 0.08 12.2 0.0 0.098 11.9 0.0 1.2 1 0 0 1 1 1 0 Alpha-helical domain 2 CPP1-like PF11833.8 ACL96402.1 - 0.016 14.8 0.9 0.028 14.1 0.9 1.4 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like OmpA PF00691.20 ACL96403.1 - 1.8e-17 63.5 0.0 2.4e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 OmpA family MCPsignal PF00015.21 ACL96405.1 - 1.1e-53 181.6 21.6 1.1e-53 181.6 21.6 3.5 2 1 2 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HA2 PF04408.23 ACL96405.1 - 0.0036 17.5 0.4 0.013 15.8 0.4 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) BLOC1_2 PF10046.9 ACL96405.1 - 0.026 14.8 10.3 18 5.7 0.1 4.6 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 ACL96405.1 - 0.054 13.5 10.9 0.42 10.7 0.7 3.6 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) DUF639 PF04842.12 ACL96405.1 - 0.2 11.1 2.2 12 5.3 0.1 2.6 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) Sec8_exocyst PF04048.14 ACL96405.1 - 0.39 10.6 4.4 5 7.0 0.1 3.0 2 2 1 3 3 3 0 Sec8 exocyst complex component specific domain GIT1_C PF12205.8 ACL96405.1 - 0.57 10.3 5.5 3.8 7.6 0.5 2.8 2 1 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term DASH_Duo1 PF08651.10 ACL96405.1 - 2.4 8.0 4.9 2.6 7.9 0.3 3.1 3 0 0 3 3 3 0 DASH complex subunit Duo1 NPV_P10 PF05531.12 ACL96405.1 - 3.4 8.2 9.4 26 5.4 0.1 4.0 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 ACL96405.1 - 5 7.1 23.8 0.39 10.7 3.6 4.0 2 1 2 4 4 4 0 Laminin Domain II GreA_GreB_N PF03449.15 ACL96406.1 - 3.9e-32 110.2 0.9 3.9e-32 110.2 0.9 1.6 2 0 0 2 2 2 1 Transcription elongation factor, N-terminal GreA_GreB PF01272.19 ACL96406.1 - 6.2e-28 96.5 0.8 9.7e-28 95.9 0.8 1.3 1 0 0 1 1 1 1 Transcription elongation factor, GreA/GreB, C-term DUF2226 PF09987.9 ACL96406.1 - 0.029 13.7 1.2 0.051 12.9 1.2 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2226) ATP-synt_ab_N PF02874.23 ACL96406.1 - 0.067 13.7 0.7 18 6.0 0.3 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, beta-barrel domain PapC_C PF13953.6 ACL96406.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 PapC C-terminal domain Mito_fiss_Elm1 PF06258.11 ACL96407.1 - 2.7e-99 332.2 0.0 3.2e-99 332.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial fission ELM1 RXLR PF16810.5 ACL96409.1 - 0.081 13.4 0.4 0.13 12.6 0.4 1.4 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity HATPase_c PF02518.26 ACL96410.1 - 1.1e-24 87.1 0.0 1.9e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 ACL96410.1 - 1.4e-24 86.4 0.9 5.1e-20 71.8 0.0 3.5 3 0 0 3 3 3 2 PAS fold Response_reg PF00072.24 ACL96410.1 - 1.9e-24 86.0 0.1 4e-24 84.9 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ACL96410.1 - 3.2e-20 71.9 0.9 1.7e-19 69.6 0.5 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 ACL96410.1 - 3.4e-14 52.8 0.0 1.1e-11 44.7 0.0 2.7 2 0 0 2 2 2 1 PAS fold PAS_7 PF12860.7 ACL96410.1 - 1.1e-13 51.3 0.0 9.7e-13 48.3 0.0 2.5 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.7 ACL96410.1 - 6.1e-09 35.7 0.1 0.00019 21.3 0.0 2.9 2 0 0 2 2 2 2 PAS domain PAS_9 PF13426.7 ACL96410.1 - 7.1e-08 32.7 0.0 1.5e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 PAS domain HATPase_c_2 PF13581.6 ACL96410.1 - 0.034 14.1 0.1 0.083 12.9 0.1 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain KR PF08659.10 ACL96410.1 - 0.096 12.6 1.4 0.15 12.0 0.1 2.0 2 0 0 2 2 2 0 KR domain CTP_transf_3 PF02348.19 ACL96411.1 - 2e-25 90.0 0.0 2.4e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 ACL96411.1 - 1.2e-09 38.7 1.6 2.8e-09 37.5 1.0 1.8 2 0 0 2 2 2 1 MobA-like NTP transferase domain DUF2064 PF09837.9 ACL96411.1 - 0.0095 15.7 0.7 0.25 11.2 0.1 2.2 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2064) Glyco_tran_28_C PF04101.16 ACL96412.1 - 0.025 14.5 0.0 0.038 14.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Methyltransf_23 PF13489.6 ACL96414.1 - 2.5e-09 37.2 0.0 3.3e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ACL96414.1 - 1.4e-08 35.3 0.0 2.3e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ACL96414.1 - 9.1e-08 32.8 0.0 1.4e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ACL96414.1 - 1.1e-06 29.1 0.0 1.7e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 ACL96414.1 - 0.041 14.9 0.0 0.067 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 ACL96414.1 - 0.24 10.8 0.1 0.38 10.1 0.1 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB NAD_binding_8 PF13450.6 ACL96415.1 - 0.00066 19.9 0.8 0.0032 17.7 0.4 2.3 1 1 1 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 ACL96415.1 - 0.007 15.8 0.1 0.014 14.7 0.2 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 ACL96415.1 - 0.011 15.3 0.8 0.056 13.0 0.4 2.2 1 1 1 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ACL96415.1 - 0.051 12.8 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ACL96415.1 - 0.076 12.1 0.0 0.18 10.9 0.1 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A WbqC PF08889.11 ACL96416.1 - 5.8e-71 238.9 0.0 6.5e-71 238.7 0.0 1.0 1 0 0 1 1 1 1 WbqC-like protein family DUF4158 PF13700.6 ACL96416.1 - 0.033 14.0 0.3 0.62 9.9 0.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4158) Branch PF02485.21 ACL96418.1 - 2.2e-38 132.2 0.0 2.9e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme adh_short PF00106.25 ACL96419.1 - 3.5e-44 150.6 0.0 4.6e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ACL96419.1 - 8.9e-31 107.2 0.0 1.4e-30 106.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ACL96419.1 - 2.4e-05 24.3 0.0 4.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 ACL96419.1 - 0.0047 16.3 0.0 0.007 15.8 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) TauE PF01925.19 ACL96420.1 - 1.8e-45 155.4 47.7 2.1e-45 155.2 47.7 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Rhodanese PF00581.20 ACL96421.1 - 1.2e-11 45.1 0.0 1.7e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain DUF2892 PF11127.8 ACL96421.1 - 2.1e-09 37.3 9.4 3.5e-09 36.6 9.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2892) HTH_5 PF01022.20 ACL96422.2 - 8.7e-16 57.5 0.2 1.8e-15 56.5 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 ACL96422.2 - 2.4e-10 40.3 3.2 4.5e-10 39.4 1.9 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_24 PF13412.6 ACL96422.2 - 0.00062 19.3 0.2 0.0036 16.8 0.1 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HxlR PF01638.17 ACL96422.2 - 0.00089 19.1 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_Crp_2 PF13545.6 ACL96422.2 - 0.0025 17.7 0.0 0.0046 16.9 0.0 1.6 1 1 0 1 1 1 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 ACL96422.2 - 0.0033 17.3 1.1 0.0067 16.3 1.0 1.5 1 1 0 1 1 1 1 MarR family HTH_IclR PF09339.10 ACL96422.2 - 0.0041 16.9 1.9 0.0057 16.4 0.3 1.9 1 1 1 2 2 2 1 IclR helix-turn-helix domain Rrf2 PF02082.20 ACL96422.2 - 0.013 15.8 0.1 0.026 14.9 0.1 1.6 1 1 0 1 1 1 0 Transcriptional regulator TrmB PF01978.19 ACL96422.2 - 0.044 13.7 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_34 PF13601.6 ACL96422.2 - 0.092 12.9 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain HNF-1_N PF04814.13 ACL96422.2 - 0.1 13.2 0.0 0.12 13.0 0.0 1.3 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus HTH_1 PF00126.27 ACL96422.2 - 0.26 11.3 0.1 0.26 11.3 0.1 2.3 3 0 0 3 3 3 0 Bacterial regulatory helix-turn-helix protein, lysR family Lactamase_B PF00753.27 ACL96424.1 - 2.2e-27 96.4 2.9 2.2e-27 96.4 2.9 1.4 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ACL96424.1 - 1.1e-07 31.5 0.3 1.7e-07 31.0 0.3 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain HTH_3 PF01381.22 ACL96425.1 - 2.5e-06 27.5 0.0 3.3e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 ACL96425.1 - 0.0016 18.8 0.0 0.0021 18.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 ACL96425.1 - 0.069 13.1 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_19 PF12844.7 ACL96425.1 - 0.085 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain NeuB PF03102.14 ACL96426.1 - 7.6e-88 294.0 0.0 8.9e-88 293.8 0.0 1.0 1 0 0 1 1 1 1 NeuB family SAF PF08666.12 ACL96426.1 - 9.5e-10 39.0 0.0 2e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 SAF domain Phage_TAC_6 PF09550.10 ACL96426.1 - 0.12 12.8 0.1 1.4 9.4 0.0 2.6 3 0 0 3 3 3 0 Phage tail assembly chaperone protein, TAC HicB_lk_antitox PF15919.5 ACL96427.1 - 1.4e-10 41.4 0.0 1.4e-10 41.3 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system DUF3482 PF11981.8 ACL96428.1 - 0.8 9.0 17.7 0.85 9.0 17.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) ATP-synt_C PF00137.21 ACL96428.1 - 2.2 8.7 16.2 0.44 10.9 8.3 2.3 1 1 1 2 2 2 0 ATP synthase subunit C Pyr_redox_2 PF07992.14 ACL96429.3 - 1e-52 179.2 2.4 1.2e-52 179.0 2.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ACL96429.3 - 1.2e-21 77.3 1.8 2e-18 66.7 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ACL96429.3 - 1.1e-16 61.1 1.0 1.2e-15 57.8 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ACL96429.3 - 4.9e-07 29.2 9.1 0.039 13.0 0.1 4.9 3 1 2 5 5 5 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 ACL96429.3 - 2.5e-06 26.8 10.0 0.0045 16.1 0.3 4.3 2 1 2 4 4 4 2 FAD binding domain NAD_binding_7 PF13241.6 ACL96429.3 - 3.2e-06 27.5 0.0 0.0047 17.4 0.0 2.6 2 1 0 2 2 2 2 Putative NAD(P)-binding DAO PF01266.24 ACL96429.3 - 8.8e-05 22.2 4.6 0.18 11.4 0.0 3.8 4 0 0 4 4 4 2 FAD dependent oxidoreductase HI0933_like PF03486.14 ACL96429.3 - 0.00013 20.8 0.9 0.76 8.4 0.2 3.5 4 0 0 4 4 4 2 HI0933-like protein NAD_binding_9 PF13454.6 ACL96429.3 - 0.00042 20.3 3.1 0.089 12.8 0.0 3.8 4 0 0 4 4 4 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 ACL96429.3 - 0.00051 19.5 3.1 0.0047 16.3 0.0 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 ACL96429.3 - 0.0021 17.3 0.1 0.03 13.5 0.0 2.3 1 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 ACL96429.3 - 0.009 15.3 0.6 0.67 9.2 0.1 2.5 2 1 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 ACL96429.3 - 0.037 13.3 0.9 1.8 7.7 0.1 2.5 2 1 1 3 3 3 0 FAD binding domain NAD_binding_8 PF13450.6 ACL96429.3 - 0.041 14.1 0.3 0.11 12.7 0.1 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 ACL96429.3 - 0.05 12.5 0.3 0.48 9.2 0.1 2.4 3 0 0 3 3 3 0 Tryptophan halogenase zf-C4 PF00105.18 ACL96429.3 - 0.2 12.2 0.2 0.39 11.2 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) Hydrolase_2 PF07486.12 ACL96430.1 - 2.1e-24 86.3 0.0 3.5e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Cell Wall Hydrolase Ferritin PF00210.24 ACL96431.2 - 1.7e-33 115.6 0.2 1.9e-33 115.4 0.2 1.0 1 0 0 1 1 1 1 Ferritin-like domain DUF1654 PF07867.11 ACL96431.2 - 0.052 13.3 0.3 0.75 9.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) PAS_3 PF08447.12 ACL96432.2 - 8.5e-29 99.7 0.0 2.8e-13 49.9 0.0 3.3 3 0 0 3 3 3 2 PAS fold HATPase_c PF02518.26 ACL96432.2 - 1.5e-15 57.7 0.0 2.8e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ACL96432.2 - 5.4e-15 55.5 0.0 1e-14 54.7 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain PAS PF00989.25 ACL96432.2 - 6.5e-14 51.9 0.0 8.6e-08 32.2 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 ACL96432.2 - 2.7e-09 37.3 0.6 3e-06 27.4 0.0 2.9 2 0 0 2 2 2 2 PAS fold HisKA PF00512.25 ACL96432.2 - 9.4e-08 32.0 0.1 3.3e-07 30.2 0.1 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 ACL96432.2 - 1.1e-07 32.0 0.0 0.003 17.8 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_8 PF13188.7 ACL96432.2 - 0.00019 21.4 0.0 0.00077 19.4 0.0 2.1 2 0 0 2 2 2 1 PAS domain DUF4118 PF13493.6 ACL96432.2 - 0.00045 20.0 3.6 0.0011 18.7 3.6 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4118) HATPase_c_3 PF13589.6 ACL96432.2 - 0.0039 17.0 0.0 0.008 16.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_6 PF08348.11 ACL96432.2 - 0.038 13.9 0.0 2.2 8.1 0.0 2.3 2 0 0 2 2 2 0 YheO-like PAS domain FleQ PF06490.11 ACL96432.2 - 0.049 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ 7TM-7TMR_HD PF07698.11 ACL96432.2 - 0.057 13.2 2.9 0.09 12.5 2.9 1.2 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase TetR_N PF00440.23 ACL96434.1 - 2.7e-07 30.3 0.6 1.1e-06 28.3 0.3 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_6 PF13977.6 ACL96434.1 - 4.2e-06 27.0 3.5 4.2e-06 27.0 3.5 2.4 1 1 1 2 2 2 1 BetI-type transcriptional repressor, C-terminal TetR_C_31 PF17940.1 ACL96434.1 - 0.00031 20.9 6.2 0.00031 20.9 6.2 2.6 1 1 2 3 3 3 1 Tetracyclin repressor-like, C-terminal domain DUF393 PF04134.12 ACL96435.1 - 6.5e-20 72.6 0.5 7.4e-20 72.4 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF393 AI-2E_transport PF01594.16 ACL96436.1 - 2.4e-30 105.8 36.4 5e-30 104.8 36.4 1.5 1 1 0 1 1 1 1 AI-2E family transporter 2OG-FeII_Oxy_5 PF13759.6 ACL96437.2 - 2.7e-36 124.0 0.0 4.1e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 ACL96437.2 - 0.0097 16.8 0.0 0.015 16.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ParD PF09386.10 ACL96438.2 - 0.0071 16.7 0.0 0.0094 16.3 0.0 1.1 1 0 0 1 1 1 1 Antitoxin ParD RHH_5 PF07878.11 ACL96438.2 - 0.15 12.0 0.2 0.29 11.0 0.0 1.5 2 0 0 2 2 2 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 ParE_toxin PF05016.15 ACL96439.1 - 9e-17 61.5 1.3 9.7e-17 61.4 1.3 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE UvrC_HhH_N PF08459.11 ACL96440.1 - 3e-52 176.6 0.0 7.1e-52 175.4 0.0 1.7 1 0 0 1 1 1 1 UvrC Helix-hairpin-helix N-terminal UVR PF02151.19 ACL96440.1 - 3.2e-09 36.2 7.6 4.7e-09 35.7 6.1 2.1 2 0 0 2 2 2 1 UvrB/uvrC motif GIY-YIG PF01541.24 ACL96440.1 - 9.1e-09 35.5 0.0 1.9e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain HHH_5 PF14520.6 ACL96440.1 - 2.3e-06 28.1 0.0 6.5e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 ACL96440.1 - 6.4e-06 26.2 0.0 1.2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 ACL96440.1 - 9.1e-05 22.1 0.1 0.006 16.4 0.0 3.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_3 PF12836.7 ACL96440.1 - 0.13 12.5 0.0 0.36 11.1 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Lumazine_bd_2 PF12893.7 ACL96440.1 - 0.15 12.8 0.4 0.34 11.6 0.4 1.6 1 0 0 1 1 1 0 Putative lumazine-binding ABATE PF07336.11 ACL96440.1 - 4.8 7.8 7.8 0.52 11.0 1.4 2.8 3 0 0 3 3 3 0 Putative stress-induced transcription regulator CZB PF13682.6 ACL96441.2 - 1.2e-05 25.6 1.9 2.1e-05 24.8 1.6 1.7 2 0 0 2 2 2 1 Chemoreceptor zinc-binding domain Sigma70_r4_2 PF08281.12 ACL96442.1 - 2.3e-17 62.4 0.1 4.4e-17 61.5 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 ACL96442.1 - 5.4e-13 48.5 0.4 1.2e-12 47.4 0.4 1.6 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 ACL96442.1 - 2.4e-06 27.0 0.1 4.3e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 ACL96442.1 - 4e-05 23.6 0.3 4.9e-05 23.3 0.3 1.3 1 0 0 1 1 1 1 ECF sigma factor DUF746 PF05344.11 ACL96442.1 - 0.008 16.0 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF746) DUF3686 PF12458.8 ACL96442.1 - 0.069 11.6 0.0 0.095 11.2 0.0 1.1 1 0 0 1 1 1 0 ATPase involved in DNA repair HTH_28 PF13518.6 ACL96442.1 - 0.071 13.2 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HATPase_c PF02518.26 ACL96443.1 - 4.4e-11 43.3 0.0 8.4e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ACL96443.1 - 6.1e-10 39.0 0.1 2e-09 37.3 0.0 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 ACL96443.1 - 0.0006 19.8 0.0 0.0015 18.5 0.0 1.7 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain Aminotran_5 PF00266.19 ACL96444.3 - 7.4e-07 28.4 0.0 1.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Trp_dioxygenase PF03301.13 ACL96445.1 - 1e-66 225.6 0.3 1.2e-39 136.7 0.0 2.9 1 1 1 2 2 2 2 Tryptophan 2,3-dioxygenase Hs1pro-1_C PF07014.12 ACL96445.1 - 0.027 14.0 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 Hs1pro-1 protein C-terminus AsnC_trans_reg PF01037.21 ACL96446.2 - 5.1e-20 71.2 0.0 7.4e-20 70.7 0.0 1.2 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_24 PF13412.6 ACL96446.2 - 6.8e-18 64.0 0.0 1.3e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 ACL96446.2 - 4.3e-16 58.5 0.3 8.2e-16 57.6 0.3 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain MarR_2 PF12802.7 ACL96446.2 - 0.0002 21.2 0.6 0.0021 17.9 0.2 2.2 2 0 0 2 2 2 1 MarR family HTH_Crp_2 PF13545.6 ACL96446.2 - 0.00022 21.1 0.1 0.52 10.3 0.0 2.2 2 0 0 2 2 2 2 Crp-like helix-turn-helix domain HTH_11 PF08279.12 ACL96446.2 - 0.00039 20.3 0.0 0.00075 19.4 0.0 1.5 1 0 0 1 1 1 1 HTH domain HTH_20 PF12840.7 ACL96446.2 - 0.00052 20.0 0.2 0.0016 18.4 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain MarR PF01047.22 ACL96446.2 - 0.0015 18.4 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 ACL96446.2 - 0.0071 16.1 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_1 PF00126.27 ACL96446.2 - 0.022 14.7 0.1 0.047 13.7 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_34 PF13601.6 ACL96446.2 - 0.069 13.3 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain Fe_dep_repress PF01325.19 ACL96446.2 - 0.13 12.4 0.0 3.7 7.8 0.0 2.1 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain OprB PF04966.12 ACL96447.1 - 2e-62 211.8 4.0 2.4e-62 211.6 4.0 1.0 1 0 0 1 1 1 1 Carbohydrate-selective porin, OprB family Glycos_transf_2 PF00535.26 ACL96448.1 - 1e-27 97.1 0.1 1.6e-27 96.4 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ACL96448.1 - 1.3e-06 28.5 0.0 2e-06 27.9 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 ACL96448.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 ACL96448.1 - 0.18 11.2 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 GtrA PF04138.14 ACL96449.1 - 3.5e-19 69.2 11.3 4.3e-19 68.9 11.3 1.1 1 0 0 1 1 1 1 GtrA-like protein Abhydrolase_9_N PF15420.6 ACL96449.1 - 0.14 12.2 6.9 0.58 10.1 6.9 2.0 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus Methyltransf_23 PF13489.6 ACL96450.1 - 8.7e-15 54.9 0.0 1.4e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ACL96450.1 - 7.1e-14 52.2 0.0 1.3e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ACL96450.1 - 7e-10 39.5 0.0 1.3e-09 38.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ACL96450.1 - 9.7e-08 32.7 0.1 4e-07 30.7 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ACL96450.1 - 1.4e-06 28.2 0.1 5.8e-06 26.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 ACL96450.1 - 0.00042 20.0 0.0 0.00051 19.7 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_29 PF03141.16 ACL96450.1 - 0.014 14.0 0.0 0.018 13.6 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase CMAS PF02353.20 ACL96450.1 - 0.047 13.0 0.0 0.11 11.7 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF4131 PF13567.6 ACL96452.1 - 0.0011 18.7 0.0 0.0012 18.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) RCR PF12273.8 ACL96452.1 - 0.077 13.6 0.0 0.092 13.4 0.0 1.1 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Glyoxalase PF00903.25 ACL96453.1 - 0.0044 17.2 0.1 0.0093 16.2 0.1 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ACL96453.1 - 0.03 14.6 0.0 0.21 11.9 0.0 2.1 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 ACL96453.1 - 0.12 12.3 0.0 0.32 10.9 0.0 1.7 1 1 0 1 1 1 0 Glyoxalase-like domain DAZAP2 PF11029.8 ACL96454.1 - 0.025 15.5 0.2 0.039 14.9 0.2 1.4 1 0 0 1 1 1 0 DAZ associated protein 2 (DAZAP2) DDE_Tnp_1_2 PF13586.6 ACL96456.1 - 1.6e-20 73.3 0.2 2.4e-20 72.7 0.2 1.3 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 ACL96456.1 - 1.6e-18 67.2 2.7 5.7e-17 62.1 2.7 2.0 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_3 PF13612.6 ACL96456.1 - 1.9e-08 34.5 0.0 2.3e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 ACL96456.1 - 2.1e-05 24.3 0.0 2.4e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2269 PF10027.9 ACL96457.1 - 5.9e-61 204.9 15.0 6.7e-61 204.7 15.0 1.0 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2269) DoxX_3 PF13781.6 ACL96458.1 - 3.3e-24 85.5 8.6 1.1e-23 83.8 8.6 1.9 1 0 0 1 1 1 1 DoxX-like family NAD_binding_10 PF13460.6 ACL96458.1 - 4.3e-15 56.1 3.4 1.2e-14 54.7 2.2 2.1 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 ACL96458.1 - 9.1e-10 38.4 0.1 2.1e-09 37.2 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 ACL96458.1 - 4.8e-08 32.5 0.2 0.0026 17.0 0.0 2.8 2 1 1 3 3 3 2 Male sterility protein RmlD_sub_bind PF04321.17 ACL96458.1 - 1e-07 31.3 0.4 1.7e-07 30.6 0.4 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 ACL96458.1 - 0.018 14.6 0.5 0.037 13.6 0.2 1.6 2 0 0 2 2 2 0 NmrA-like family 3Beta_HSD PF01073.19 ACL96458.1 - 0.064 12.2 0.2 0.24 10.4 0.2 1.8 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 ACL96458.1 - 0.11 11.9 0.6 0.53 9.7 0.6 2.1 1 1 0 1 1 1 0 short chain dehydrogenase Semialdhyde_dh PF01118.24 ACL96458.1 - 0.47 10.9 2.3 14 6.1 0.3 3.3 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain CPSase_L_D2 PF02786.17 ACL96459.1 - 6.1e-102 339.6 0.0 1.5e-68 230.5 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 ACL96459.1 - 1.6e-37 128.5 0.0 3.1e-37 127.6 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain MGS PF02142.22 ACL96459.1 - 6.9e-20 71.0 0.1 3.3e-19 68.9 0.0 2.3 2 0 0 2 2 2 1 MGS-like domain ATP-grasp PF02222.22 ACL96459.1 - 1.4e-11 44.3 0.0 5.1e-06 26.2 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.14 ACL96459.1 - 5.3e-09 36.3 0.0 0.00072 19.6 0.0 3.5 3 0 0 3 3 3 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 ACL96459.1 - 2.2e-07 30.6 0.0 0.022 14.3 0.0 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 ACL96459.1 - 2.3e-07 30.6 0.0 0.0034 17.1 0.0 2.7 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.6 ACL96459.1 - 1.1e-05 25.1 0.1 0.076 12.6 0.0 3.6 3 2 0 3 3 3 2 ATP-grasp domain RimK PF08443.11 ACL96459.1 - 0.00019 21.1 0.0 0.0091 15.6 0.0 3.1 3 0 0 3 3 3 1 RimK-like ATP-grasp domain GST_N PF02798.20 ACL96460.1 - 1.2e-09 38.4 0.0 2.2e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ACL96460.1 - 1.5e-09 38.2 0.0 2.9e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ACL96460.1 - 5.1e-06 26.6 0.0 9e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ACL96460.1 - 0.00033 20.6 1.3 0.0016 18.4 0.9 2.2 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ACL96460.1 - 0.00035 20.7 0.0 0.00056 20.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ACL96460.1 - 0.0018 18.6 0.0 0.0038 17.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 ACL96460.1 - 0.094 12.5 0.0 0.66 9.8 0.0 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Patatin PF01734.22 ACL96461.1 - 1.6e-18 67.6 1.3 2.6e-18 66.9 1.3 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase CSD PF00313.22 ACL96462.1 - 6.2e-22 77.2 0.0 6.6e-22 77.1 0.0 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 ACL96462.1 - 0.00012 21.6 0.1 0.00017 21.2 0.1 1.3 1 0 0 1 1 1 1 Ribonuclease B OB domain DUF2063 PF09836.9 ACL96464.1 - 1.2e-20 73.5 0.1 2.1e-20 72.7 0.1 1.4 1 0 0 1 1 1 1 Putative DNA-binding domain DUF692 PF05114.13 ACL96465.2 - 8.3e-109 362.8 0.0 9.4e-109 362.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF692) REF PF05755.12 ACL96465.2 - 0.14 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) DUF4179 PF13786.6 ACL96466.2 - 0.042 14.3 0.1 0.051 14.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) CDP-OH_P_transf PF01066.21 ACL96467.1 - 3.2e-13 50.2 0.5 3.2e-13 50.2 0.5 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase HWE_HK PF07536.14 ACL96468.1 - 2.1e-21 76.4 0.0 6.2e-21 74.9 0.0 1.8 1 0 0 1 1 1 1 HWE histidine kinase dCache_1 PF02743.18 ACL96468.1 - 6.1e-10 39.3 0.0 3.6e-09 36.8 0.0 2.0 2 0 0 2 2 2 1 Cache domain HisKA_2 PF07568.12 ACL96468.1 - 0.0001 22.3 0.0 0.00036 20.6 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase Bestrophin PF01062.21 ACL96468.1 - 0.082 12.3 0.0 0.25 10.7 0.0 1.7 1 1 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel DUF485 PF04341.12 ACL96468.1 - 0.12 12.3 0.3 0.84 9.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF485 dCache_3 PF14827.6 ACL96468.1 - 0.13 11.9 1.9 0.11 12.2 0.1 1.8 2 1 0 2 2 2 0 Double sensory domain of two-component sensor kinase AAA_33 PF13671.6 ACL96469.1 - 3.9e-05 23.9 0.6 0.00082 19.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain MobB PF03205.14 ACL96469.1 - 0.00041 20.3 0.0 0.003 17.5 0.0 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MeaB PF03308.16 ACL96469.1 - 0.00066 18.7 0.0 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 ACL96469.1 - 0.0012 19.2 4.6 0.0089 16.4 3.4 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 ACL96469.1 - 0.0013 19.3 0.0 0.0034 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 ACL96469.1 - 0.0024 18.0 0.1 0.0043 17.1 0.1 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 ACL96469.1 - 0.0027 17.0 0.0 0.0075 15.6 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin ABC_tran PF00005.27 ACL96469.1 - 0.0055 17.2 0.0 0.0087 16.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter PRK PF00485.18 ACL96469.1 - 0.0057 16.4 0.0 0.012 15.3 0.0 1.5 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.6 ACL96469.1 - 0.0078 16.5 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 ACL96469.1 - 0.0096 15.9 0.0 0.025 14.5 0.0 1.7 2 0 0 2 2 2 1 NACHT domain APS_kinase PF01583.20 ACL96469.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase IstB_IS21 PF01695.17 ACL96469.1 - 0.02 14.6 0.2 0.098 12.4 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein ATP_bind_1 PF03029.17 ACL96469.1 - 0.032 14.0 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 ACL96469.1 - 0.032 14.0 0.0 0.05 13.4 0.0 1.2 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_29 PF13555.6 ACL96469.1 - 0.042 13.6 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 ACL96469.1 - 0.047 13.9 0.4 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 ACL96469.1 - 0.049 12.8 0.0 0.071 12.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain SRP54 PF00448.22 ACL96469.1 - 0.063 12.9 0.0 0.095 12.3 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 ACL96469.1 - 0.086 13.2 0.0 0.23 11.9 0.0 1.7 2 0 0 2 2 1 0 RNA helicase Cytidylate_kin PF02224.18 ACL96469.1 - 0.094 12.4 0.2 0.46 10.2 0.1 1.9 2 0 0 2 2 2 0 Cytidylate kinase NTPase_1 PF03266.15 ACL96469.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 NTPase AAA_30 PF13604.6 ACL96469.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain MipZ PF09140.11 ACL96469.1 - 0.17 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 ATPase MipZ DUF87 PF01935.17 ACL96469.1 - 0.18 11.9 0.1 0.29 11.2 0.1 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain KTI12 PF08433.10 ACL96469.1 - 0.24 10.8 0.0 0.4 10.1 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RNA12 PF10443.9 ACL96469.1 - 0.3 9.8 0.0 0.42 9.3 0.0 1.1 1 0 0 1 1 1 0 RNA12 protein NadA PF02445.16 ACL96471.2 - 9.5e-110 366.4 3.5 1.1e-109 366.2 3.5 1.0 1 0 0 1 1 1 1 Quinolinate synthetase A protein FAD_binding_2 PF00890.24 ACL96472.1 - 8.2e-88 295.3 18.2 1.2e-87 294.7 18.2 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 ACL96472.1 - 9.1e-10 38.6 0.0 3.7e-06 26.9 0.0 2.4 1 1 1 2 2 2 2 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 ACL96472.1 - 3.2e-07 29.9 3.7 0.017 14.4 2.5 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ACL96472.1 - 2.8 6.9 14.9 0.024 13.7 5.0 2.3 2 1 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 ACL96472.1 - 5.3 6.3 10.4 24 4.1 10.4 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase Uma2 PF05685.12 ACL96473.1 - 2e-29 102.4 0.0 2.2e-29 102.2 0.0 1.0 1 0 0 1 1 1 1 Putative restriction endonuclease QRPTase_C PF01729.19 ACL96474.1 - 8.1e-64 214.4 0.6 1e-63 214.1 0.6 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 ACL96474.1 - 1.4e-22 79.6 0.0 3.5e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain GST_C_2 PF13410.6 ACL96474.1 - 0.031 14.3 0.0 0.11 12.5 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ribul_P_3_epim PF00834.19 ACL96474.1 - 0.045 13.1 0.6 0.11 11.9 0.3 1.7 1 1 1 2 2 2 0 Ribulose-phosphate 3 epimerase family MAPEG PF01124.18 ACL96475.1 - 3.9e-23 81.8 6.2 4.4e-23 81.6 6.2 1.0 1 0 0 1 1 1 1 MAPEG family Lipocalin_2 PF08212.12 ACL96476.1 - 7e-40 136.3 0.0 8e-40 136.1 0.0 1.0 1 0 0 1 1 1 1 Lipocalin-like domain HCV_NS5a_1a PF08300.13 ACL96476.1 - 0.032 14.3 0.2 0.067 13.3 0.1 1.6 1 1 0 1 1 1 0 Hepatitis C virus non-structural 5a zinc finger domain AhpC-TSA PF00578.21 ACL96477.1 - 6.4e-33 113.3 0.0 8.1e-33 113.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ACL96477.1 - 6.4e-11 42.2 0.0 8.8e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 ACL96477.1 - 5.5e-07 29.3 0.1 9.6e-07 28.6 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 ACL96477.1 - 0.0004 20.3 0.0 0.0015 18.4 0.1 1.9 2 0 0 2 2 2 1 SCO1/SenC DUF3986 PF13143.6 ACL96477.1 - 0.017 16.1 0.2 0.026 15.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3986) Pyr_redox_2 PF07992.14 ACL96478.1 - 1.2e-46 159.3 2.8 1.8e-46 158.7 2.8 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ACL96478.1 - 1.8e-19 70.2 1.5 7.7e-16 58.2 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ACL96478.1 - 3.4e-14 53.1 9.8 4.8e-13 49.5 0.2 3.8 4 1 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ACL96478.1 - 2e-08 33.7 13.1 0.00081 18.6 3.1 3.8 3 2 0 4 4 4 2 Glucose inhibited division protein A Thioredoxin_3 PF13192.6 ACL96478.1 - 2.9e-07 30.4 0.0 1.7e-06 28.0 0.0 2.3 2 0 0 2 2 1 1 Thioredoxin domain HI0933_like PF03486.14 ACL96478.1 - 3.4e-06 26.0 7.1 0.098 11.3 0.3 3.2 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_2 PF00890.24 ACL96478.1 - 7.4e-05 22.0 19.7 0.055 12.5 5.8 4.4 2 2 1 4 4 4 2 FAD binding domain AlaDh_PNT_C PF01262.21 ACL96478.1 - 0.00023 20.5 4.6 0.063 12.6 0.2 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 ACL96478.1 - 0.00036 19.9 4.0 0.009 15.3 1.0 2.4 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 ACL96478.1 - 0.0005 19.5 17.2 0.0007 19.1 6.5 2.8 2 2 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 ACL96478.1 - 0.00077 19.9 0.5 0.35 11.3 0.1 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding K_oxygenase PF13434.6 ACL96478.1 - 0.00088 18.5 0.6 0.018 14.2 0.0 2.5 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Glutaredoxin PF00462.24 ACL96478.1 - 0.0011 19.1 0.6 0.0058 16.8 0.0 2.5 2 0 0 2 2 2 1 Glutaredoxin DAO PF01266.24 ACL96478.1 - 0.0017 18.0 14.3 0.24 10.9 3.8 3.3 3 0 0 3 3 3 2 FAD dependent oxidoreductase FMO-like PF00743.19 ACL96478.1 - 0.026 13.0 0.0 0.038 12.4 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ACL96478.1 - 0.064 13.5 8.5 0.16 12.3 2.6 2.8 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ACL96478.1 - 0.16 11.2 5.0 0.42 9.8 0.1 2.6 2 1 1 3 3 3 0 Thi4 family Trp_halogenase PF04820.14 ACL96478.1 - 1.3 7.8 8.0 3.8 6.2 0.4 2.4 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.6 ACL96478.1 - 3.9 7.4 6.0 52 3.8 0.0 3.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 ACL96478.1 - 6.9 6.5 5.6 14 5.5 0.1 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Wzy_C PF04932.15 ACL96479.1 - 0.038 13.6 2.6 0.77 9.4 0.8 2.2 2 0 0 2 2 2 0 O-Antigen ligase GerE PF00196.19 ACL96481.2 - 5.1e-05 22.7 0.0 8.2e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 ACL96481.2 - 0.0022 17.6 0.1 0.0046 16.6 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_40 PF14493.6 ACL96481.2 - 0.011 16.2 0.0 0.017 15.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2749 PF10907.8 ACL96481.2 - 0.13 12.4 7.6 0.34 11.1 1.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2749) Ni_hydr_CYTB PF01292.20 ACL96482.1 - 7.1e-22 77.9 0.9 2e-21 76.4 0.9 1.7 1 1 0 1 1 1 1 Prokaryotic cytochrome b561 DUF4405 PF14358.6 ACL96482.1 - 3.7 8.2 6.7 9.9 6.8 2.2 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) DEDD_Tnp_IS110 PF01548.17 ACL96483.1 - 4.3e-20 72.1 0.0 8e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Transposase Transposase_20 PF02371.16 ACL96483.1 - 8e-18 64.5 0.2 1.9e-17 63.3 0.2 1.7 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family AP_endonuc_2 PF01261.24 ACL96483.1 - 0.098 12.1 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel TonB_dep_Rec PF00593.24 ACL96484.1 - 1.7e-35 123.8 41.0 1.7e-35 123.8 41.0 2.2 1 1 2 3 3 3 1 TonB dependent receptor OMP_b-brl_3 PF14905.6 ACL96484.1 - 3.4e-18 65.8 2.9 3.4e-18 65.8 2.9 2.3 2 0 0 2 2 2 1 Outer membrane protein beta-barrel family Plug PF07715.15 ACL96484.1 - 4.3e-14 53.0 5.6 7.2e-14 52.3 0.2 3.2 3 1 0 3 3 3 1 TonB-dependent Receptor Plug Domain PI-PLC-C1 PF16670.5 ACL96485.1 - 1.6e-123 412.0 0.0 1.8e-123 411.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoinositide phospholipase C, Ca2+-dependent PI-PLC-X PF00388.19 ACL96485.1 - 0.038 13.6 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain BTP PF05232.12 ACL96486.3 - 0.024 14.7 5.2 0.042 13.9 5.2 1.5 1 1 0 1 1 1 0 Chlorhexidine efflux transporter PepSY_TM PF03929.16 ACL96487.3 - 2.8e-57 194.6 8.7 3.4e-57 194.3 8.7 1.0 1 0 0 1 1 1 1 PepSY-associated TM region PepSY PF03413.19 ACL96487.3 - 0.0028 18.2 0.3 0.4 11.3 0.0 2.9 2 1 0 2 2 2 1 Peptidase propeptide and YPEB domain PepSY_TM_like_2 PF16357.5 ACL96487.3 - 0.0051 16.8 3.5 0.13 12.2 0.7 3.0 2 1 0 2 2 2 1 Putative PepSY_TM-like DUF4405 PF14358.6 ACL96487.3 - 0.85 10.2 14.2 0.34 11.5 0.4 4.2 3 2 2 5 5 5 0 Domain of unknown function (DUF4405) DUF1129 PF06570.11 ACL96487.3 - 1.1 8.7 5.5 0.14 11.6 1.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) TonB_dep_Rec PF00593.24 ACL96488.1 - 1.4e-41 143.9 20.0 1.4e-41 143.9 20.0 1.4 1 1 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 ACL96488.1 - 2.2e-14 53.9 0.1 6.7e-14 52.4 0.1 1.9 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain Aminotran_4 PF01063.19 ACL96489.1 - 8.2e-50 169.7 0.0 9.5e-50 169.5 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV DUF498 PF04430.14 ACL96489.1 - 0.15 12.1 0.0 0.39 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) MarR_2 PF12802.7 ACL96490.1 - 1.8e-13 50.1 2.5 2.4e-13 49.8 1.2 1.8 2 0 0 2 2 2 1 MarR family MarR PF01047.22 ACL96490.1 - 6.5e-08 32.4 0.0 1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 ACL96490.1 - 1.9e-05 24.1 0.2 5.8e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_27 PF13463.6 ACL96490.1 - 2e-05 25.0 0.1 3.2e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 ACL96490.1 - 2.4e-05 24.0 0.5 0.00045 20.0 0.2 2.6 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_5 PF01022.20 ACL96490.1 - 0.0004 20.2 0.0 0.001 18.9 0.0 1.7 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 ACL96490.1 - 0.0006 19.8 0.3 0.003 17.6 0.1 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Crp_2 PF13545.6 ACL96490.1 - 0.00066 19.6 3.1 0.0011 18.9 0.1 2.2 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain TrmB PF01978.19 ACL96490.1 - 0.00085 19.2 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 ACL96490.1 - 0.0034 17.7 0.0 0.0082 16.5 0.0 1.6 1 0 0 1 1 1 1 Transcriptional regulator DprA_WH PF17782.1 ACL96490.1 - 0.011 15.9 0.2 0.058 13.5 0.0 2.3 2 0 0 2 2 2 0 DprA winged helix domain HTH_11 PF08279.12 ACL96490.1 - 0.012 15.5 0.1 0.025 14.5 0.1 1.5 1 0 0 1 1 1 0 HTH domain HTH_36 PF13730.6 ACL96490.1 - 0.021 14.8 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2250 PF10007.9 ACL96490.1 - 0.066 13.3 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) Response_reg PF00072.24 ACL96491.1 - 1.7e-27 95.8 0.0 2.4e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 ACL96491.1 - 1.1e-16 60.6 0.8 3.1e-16 59.2 0.3 2.0 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal HATPase_c PF02518.26 ACL96492.1 - 4.7e-16 59.3 0.0 1.3e-15 57.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 ACL96492.1 - 1.7e-08 34.4 0.0 2.8e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ACL96492.1 - 4.2e-07 29.9 0.1 2e-06 27.8 0.1 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 ACL96492.1 - 0.00011 22.6 0.7 0.00037 20.8 0.7 2.0 1 0 0 1 1 1 1 HAMP domain PDT PF00800.18 ACL96493.1 - 9.9e-53 178.7 0.0 1.2e-52 178.4 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase CTP_transf_3 PF02348.19 ACL96494.1 - 3.2e-35 122.1 0.0 4.1e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 ACL96494.1 - 1e-12 48.7 0.4 1.5e-12 48.2 0.4 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Cytochrom_C PF00034.21 ACL96495.1 - 2.3e-06 28.7 0.1 2.3e-06 28.7 0.1 1.7 2 0 0 2 2 2 1 Cytochrome c Cytochrome_CBB3 PF13442.6 ACL96495.1 - 0.024 14.9 3.3 0.11 12.8 3.3 2.1 1 1 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III NLPC_P60 PF00877.19 ACL96496.1 - 4.3e-16 58.9 0.0 6.9e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 NlpC/P60 family SH3_16 PF18348.1 ACL96496.1 - 1.3e-12 47.2 0.8 3.4e-12 45.9 0.0 2.0 2 0 0 2 2 2 1 Bacterial dipeptidyl-peptidase Sh3 domain SH3_3 PF08239.11 ACL96496.1 - 0.00088 19.5 0.0 0.01 16.1 0.0 2.1 2 0 0 2 2 2 1 Bacterial SH3 domain Amidase_5 PF05382.13 ACL96496.1 - 0.018 15.0 0.0 0.053 13.4 0.0 1.8 1 1 0 1 1 1 0 Bacteriophage peptidoglycan hydrolase Peptidase_M17 PF00883.21 ACL96497.1 - 9.4e-97 324.0 0.0 1.2e-96 323.7 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 ACL96497.1 - 0.0019 18.1 3.5 0.13 12.2 3.5 2.5 1 1 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain SPP PF06550.11 ACL96497.1 - 0.1 12.0 0.2 0.18 11.3 0.2 1.3 1 0 0 1 1 1 0 Signal-peptide peptidase, presenilin aspartyl protease TPR_17 PF13431.6 ACL96498.2 - 3.8e-07 30.0 7.5 0.33 11.4 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 ACL96498.2 - 1.1e-06 29.0 23.4 0.03 14.8 2.7 4.5 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 ACL96498.2 - 5.6e-06 25.9 0.9 0.0012 18.5 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 ACL96498.2 - 9e-06 25.4 12.2 0.019 15.1 0.4 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 ACL96498.2 - 3.4e-05 24.3 28.8 0.0045 17.7 3.1 5.3 3 1 3 6 6 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 ACL96498.2 - 6.8e-05 22.8 1.3 0.048 13.9 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 ACL96498.2 - 0.00078 19.7 21.7 0.02 15.2 1.1 4.8 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 ACL96498.2 - 0.0063 16.2 5.0 7.4 6.4 0.0 4.5 3 1 1 4 4 4 1 TPR repeat TPR_16 PF13432.6 ACL96498.2 - 0.013 16.2 38.0 0.058 14.1 2.7 5.0 2 2 2 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 ACL96498.2 - 0.02 14.9 0.4 0.02 14.9 0.4 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 ACL96498.2 - 0.03 14.2 31.0 0.22 11.4 2.1 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 ACL96498.2 - 0.032 14.9 3.5 0.032 14.9 3.5 6.7 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 ACL96498.2 - 0.075 13.2 12.4 0.2 11.9 5.3 2.9 1 1 0 2 2 2 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 ACL96498.2 - 4.3 7.2 9.0 3.6 7.5 1.5 3.3 2 2 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal Flp_Fap PF04964.14 ACL96499.1 - 0.04 13.8 0.7 0.048 13.5 0.7 1.1 1 0 0 1 1 1 0 Flp/Fap pilin component T2SSF PF00482.23 ACL96500.1 - 2.6e-19 69.4 3.2 2.6e-19 69.4 3.2 2.2 2 1 0 2 2 2 1 Type II secretion system (T2SS), protein F DUF1414 PF07208.11 ACL96500.1 - 0.018 15.0 0.0 0.049 13.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1414) DUF4227 PF14004.6 ACL96500.1 - 0.099 12.6 0.0 0.34 10.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) T2SSF PF00482.23 ACL96501.1 - 2.4e-20 72.8 0.0 2.4e-20 72.8 0.0 2.3 2 2 0 2 2 2 1 Type II secretion system (T2SS), protein F T2SSE PF00437.20 ACL96502.1 - 1.6e-77 260.2 0.1 2.9e-77 259.4 0.0 1.4 2 0 0 2 2 2 1 Type II/IV secretion system protein ABC_tran PF00005.27 ACL96502.1 - 0.0002 21.9 0.0 0.00076 20.0 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 ACL96502.1 - 0.0016 18.1 0.0 0.0045 16.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 ACL96502.1 - 0.0023 17.3 0.1 0.0066 15.8 0.0 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family cobW PF02492.19 ACL96502.1 - 0.008 15.8 0.1 0.031 13.9 0.0 2.1 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 ACL96502.1 - 0.013 15.8 0.1 0.14 12.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 ACL96502.1 - 0.014 15.7 0.1 0.033 14.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 ACL96502.1 - 0.024 15.0 0.1 0.092 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.6 ACL96502.1 - 0.026 14.9 1.3 0.19 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 ACL96502.1 - 0.037 13.3 0.1 0.25 10.6 0.0 2.0 2 0 0 2 2 2 0 Septin AAA_23 PF13476.6 ACL96502.1 - 0.039 14.5 1.9 0.088 13.3 0.9 1.9 2 0 0 2 2 2 0 AAA domain DUF5132 PF17195.4 ACL96502.1 - 0.066 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF5132) Zeta_toxin PF06414.12 ACL96502.1 - 0.07 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.21 ACL96502.1 - 0.077 12.4 0.0 0.18 11.1 0.0 1.6 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 ACL96502.1 - 0.15 11.7 0.0 0.46 10.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain SpoVIF PF14069.6 ACL96502.1 - 0.45 10.3 2.4 0.4 10.5 0.4 1.9 2 0 0 2 2 2 0 Stage VI sporulation protein F AAA_31 PF13614.6 ACL96503.1 - 9.7e-09 35.4 0.0 4.5e-08 33.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 ACL96503.1 - 8e-06 25.5 0.8 6.9e-05 22.4 0.2 2.3 2 1 0 2 2 2 1 Cellulose biosynthesis protein BcsQ ParA PF10609.9 ACL96503.1 - 2.4e-05 23.9 0.3 0.0003 20.3 0.2 2.3 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 ACL96503.1 - 0.0012 18.9 0.0 0.0045 17.0 0.0 1.9 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 ACL96503.1 - 0.0016 17.9 0.0 0.72 9.3 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 ACL96503.1 - 0.021 14.0 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase MipZ PF09140.11 ACL96503.1 - 0.18 11.1 0.0 1.3 8.3 0.0 2.1 1 1 0 1 1 1 0 ATPase MipZ Pilus_CpaD PF09476.10 ACL96504.1 - 4.1e-49 167.0 0.5 5e-49 166.8 0.5 1.0 1 0 0 1 1 1 1 Pilus biogenesis CpaD protein (pilus_cpaD) Secretin PF00263.21 ACL96505.1 - 1.6e-35 122.2 0.0 3.9e-35 121.0 0.0 1.7 1 0 0 1 1 1 1 Bacterial type II and III secretion system protein T2SS-T3SS_pil_N PF13629.6 ACL96505.1 - 1.7e-18 66.1 1.0 5.5e-17 61.3 0.1 2.7 2 0 0 2 2 2 1 Pilus formation protein N terminal region BON PF04972.17 ACL96505.1 - 9e-09 35.5 0.0 2.1e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 BON domain CSTF2_hinge PF14327.6 ACL96505.1 - 0.0045 17.4 0.1 0.0099 16.3 0.1 1.5 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RcpC PF16976.5 ACL96506.1 - 2.6e-30 104.8 1.8 4.9e-30 104.0 1.8 1.5 1 0 0 1 1 1 1 Flp pilus assembly protein RcpC/CpaB SAF PF08666.12 ACL96506.1 - 8.3e-08 32.8 1.3 2.7e-07 31.1 1.3 1.9 1 1 0 1 1 1 1 SAF domain Peptidase_A24 PF01478.18 ACL96507.1 - 7.2e-13 48.9 16.2 7.2e-13 48.9 16.2 1.5 2 0 0 2 2 2 1 Type IV leader peptidase family Claudin_3 PF06653.11 ACL96507.1 - 3.4 7.6 6.8 1.5 8.7 4.3 1.6 1 1 0 1 1 1 0 Tight junction protein, Claudin-like Flp_Fap PF04964.14 ACL96508.1 - 7.9e-22 76.8 5.5 9.5e-22 76.6 5.5 1.1 1 0 0 1 1 1 1 Flp/Fap pilin component Flp1_like PF16982.5 ACL96508.1 - 0.0024 17.3 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 Putative Flagellin, Flp1-like, domain T2SS-T3SS_pil_N PF13629.6 ACL96509.1 - 3.7e-19 68.2 1.8 6e-19 67.5 1.8 1.3 1 0 0 1 1 1 1 Pilus formation protein N terminal region TadE PF07811.12 ACL96510.1 - 4.4e-12 46.1 5.5 8.9e-12 45.1 5.5 1.6 1 0 0 1 1 1 1 TadE-like protein Tad PF13400.6 ACL96510.1 - 0.0071 16.6 2.4 0.019 15.3 2.4 1.8 1 0 0 1 1 1 1 Putative Flp pilus-assembly TadE/G-like Flp_Fap PF04964.14 ACL96510.1 - 0.34 10.8 3.9 0.2 11.5 1.6 2.0 2 1 0 2 2 2 0 Flp/Fap pilin component TadE PF07811.12 ACL96511.1 - 1.2e-09 38.3 0.4 2.1e-09 37.5 0.4 1.5 1 0 0 1 1 1 1 TadE-like protein Flp_Fap PF04964.14 ACL96511.1 - 0.00024 20.9 0.1 0.00058 19.6 0.0 1.7 2 0 0 2 2 2 1 Flp/Fap pilin component Tad PF13400.6 ACL96511.1 - 0.0024 18.1 0.8 0.0042 17.3 0.8 1.4 1 0 0 1 1 1 1 Putative Flp pilus-assembly TadE/G-like TadF PF16964.5 ACL96511.1 - 0.0033 17.2 0.0 0.0045 16.8 0.0 1.2 1 0 0 1 1 1 1 Putative tight adherence pilin protein F GST_C_5 PF16865.5 ACL96511.1 - 0.046 14.3 0.0 0.066 13.8 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Aminotran_4 PF01063.19 ACL96512.1 - 4.5e-50 170.6 0.0 5.1e-50 170.4 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV Chorismate_bind PF00425.18 ACL96513.1 - 6.9e-88 294.5 0.0 8.8e-88 294.2 0.0 1.1 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 ACL96513.1 - 3.6e-10 40.2 0.0 7.5e-10 39.2 0.0 1.6 1 1 0 1 1 1 1 Anthranilate synthase component I, N terminal region ATG22 PF11700.8 ACL96514.1 - 1.6e-21 76.5 14.7 1.8e-20 73.1 14.7 2.4 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 ACL96514.1 - 9.9e-07 28.0 35.6 9.9e-07 28.0 35.6 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Y_phosphatase3 PF13350.6 ACL96515.1 - 1.3e-58 198.7 0.1 1.5e-58 198.5 0.1 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 ACL96515.1 - 0.0011 18.8 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ACL96515.1 - 0.0028 17.3 0.0 0.0037 16.9 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.14 ACL96515.1 - 0.0061 15.5 0.0 0.0097 14.9 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase2 PF03162.13 ACL96515.1 - 0.056 13.0 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 ACL96515.1 - 0.057 13.5 0.0 0.09 12.9 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF442 PF04273.13 ACL96515.1 - 0.15 12.2 0.0 7.4 6.7 0.0 2.4 2 0 0 2 2 2 0 Putative phosphatase (DUF442) GH43_C PF16369.5 ACL96516.1 - 0.011 16.3 0.0 0.015 15.9 0.0 1.2 1 0 0 1 1 1 0 C-terminal lipocalin-like domain Acyl_transf_3 PF01757.22 ACL96517.2 - 1.3e-24 86.9 31.1 1.6e-24 86.7 31.1 1.0 1 0 0 1 1 1 1 Acyltransferase family LigB PF02900.18 ACL96518.1 - 3.9e-31 108.1 0.0 4.9e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase PQQ_3 PF13570.6 ACL96518.1 - 0.095 13.2 0.0 0.44 11.1 0.0 2.2 1 0 0 1 1 1 0 PQQ-like domain DJ-1_PfpI PF01965.24 ACL96519.2 - 1.1e-25 90.4 0.0 1.4e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family SNO PF01174.19 ACL96519.2 - 0.18 11.7 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 SNO glutamine amidotransferase family HTH_18 PF12833.7 ACL96520.1 - 1e-22 80.2 0.4 1.9e-22 79.3 0.4 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain DJ-1_PfpI PF01965.24 ACL96520.1 - 1.9e-20 73.3 0.0 2.7e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family HTH_AraC PF00165.23 ACL96520.1 - 2.7e-15 56.0 0.0 3.3e-09 36.6 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family DUF4081 PF13312.6 ACL96520.1 - 0.21 11.8 4.7 3.3 8.0 0.2 3.1 2 1 0 3 3 3 0 Domain of unknown function (DUF4081) LEH PF07858.12 ACL96521.1 - 1.4e-50 170.6 0.0 1.5e-50 170.5 0.0 1.0 1 0 0 1 1 1 1 Limonene-1,2-epoxide hydrolase catalytic domain SnoaL_2 PF12680.7 ACL96521.1 - 4.5e-16 59.4 0.2 5.4e-16 59.1 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 ACL96521.1 - 7.4e-09 35.5 0.1 4.6e-07 29.7 0.1 2.0 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_3 PF13474.6 ACL96521.1 - 0.0018 18.5 0.0 0.0033 17.7 0.0 1.5 1 1 1 2 2 2 1 SnoaL-like domain DUF4440 PF14534.6 ACL96521.1 - 0.042 14.2 0.0 0.055 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Glyoxalase PF00903.25 ACL96522.1 - 1.2e-08 35.2 0.0 5.3e-08 33.1 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ACL96522.1 - 1.5e-08 35.3 0.6 1.8e-08 35.1 0.6 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain TxDE PF18711.1 ACL96522.1 - 0.017 15.2 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 Toxoflavin-degrading enzyme Glyoxalase_4 PF13669.6 ACL96522.1 - 0.039 14.2 0.1 0.091 13.0 0.1 1.9 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CN_hydrolase PF00795.22 ACL96523.1 - 3.7e-25 88.7 0.0 6.7e-25 87.9 0.0 1.4 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase DUF1003 PF06210.11 ACL96524.2 - 2.5e-37 127.1 0.4 4.3e-37 126.4 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1003) DUF1508 PF07411.12 ACL96525.1 - 1.8e-15 56.5 0.7 2.1e-15 56.3 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1508) adh_short PF00106.25 ACL96526.1 - 3.7e-45 153.8 0.0 4.7e-45 153.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ACL96526.1 - 1e-36 126.6 0.1 1.3e-36 126.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ACL96526.1 - 5.5e-07 29.7 0.1 3.5e-06 27.0 0.1 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ACL96526.1 - 0.086 12.3 0.0 0.57 9.6 0.0 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF5603 PF18231.1 ACL96526.1 - 0.19 12.1 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5603) Hydrolase_2 PF07486.12 ACL96527.1 - 1.7e-26 93.1 0.1 2.6e-26 92.5 0.1 1.3 1 0 0 1 1 1 1 Cell Wall Hydrolase PadR PF03551.14 ACL96529.2 - 1.8e-18 66.3 0.4 2.4e-18 65.8 0.4 1.2 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family MarR PF01047.22 ACL96529.2 - 0.0028 17.5 0.0 0.0052 16.7 0.0 1.4 1 0 0 1 1 1 1 MarR family DUF505 PF04458.12 ACL96529.2 - 0.0061 15.0 0.0 0.0067 14.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF505) HTH_34 PF13601.6 ACL96529.2 - 0.0094 16.1 0.0 0.015 15.4 0.0 1.4 1 1 0 1 1 1 1 Winged helix DNA-binding domain HTH_27 PF13463.6 ACL96529.2 - 0.012 16.1 0.1 0.02 15.4 0.1 1.5 1 1 0 1 1 1 0 Winged helix DNA-binding domain PaaX PF07848.12 ACL96529.2 - 0.031 14.5 0.2 0.059 13.6 0.2 1.7 1 1 0 1 1 1 0 PaaX-like protein DUF4905 PF16248.5 ACL96529.2 - 0.094 12.6 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4905) Cytochrom_C PF00034.21 ACL96530.1 - 2e-10 41.7 0.0 2.4e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 ACL96530.1 - 0.00017 21.9 0.0 0.00034 20.9 0.0 1.5 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 ACL96530.1 - 0.21 11.3 0.0 1.2 8.9 0.0 1.9 2 0 0 2 2 2 0 Cytochrome c-550 domain HATPase_c PF02518.26 ACL96531.2 - 1.9e-27 96.0 0.0 3.5e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ACL96531.2 - 4.7e-26 91.2 0.0 1e-25 90.0 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ACL96531.2 - 1.2e-18 66.9 0.5 1.2e-18 66.9 0.5 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 ACL96531.2 - 7.9e-13 49.2 0.1 7.8e-12 46.0 0.1 2.6 2 1 0 2 2 2 1 GAF domain PAS_4 PF08448.10 ACL96531.2 - 8.5e-10 38.9 0.1 3.4e-09 36.9 0.0 2.1 2 0 0 2 2 2 1 PAS fold GAF_2 PF13185.6 ACL96531.2 - 1.8e-09 38.0 1.1 2.1e-08 34.5 0.4 2.9 2 0 0 2 2 2 1 GAF domain PAS_8 PF13188.7 ACL96531.2 - 8.2e-07 28.9 0.0 3.2e-06 27.0 0.0 2.0 1 0 0 1 1 1 1 PAS domain GAF_3 PF13492.6 ACL96531.2 - 2.1e-05 24.9 0.2 0.00074 19.9 0.1 2.5 2 0 0 2 2 2 1 GAF domain PAS PF00989.25 ACL96531.2 - 2.6e-05 24.2 0.0 0.00015 21.7 0.0 2.2 2 1 0 2 2 2 1 PAS fold PAS_9 PF13426.7 ACL96531.2 - 0.00075 19.7 0.0 0.0019 18.4 0.0 1.8 1 0 0 1 1 1 1 PAS domain HxlR PF01638.17 ACL96532.2 - 1.5e-23 82.4 0.0 1.8e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix Replic_Relax PF13814.6 ACL96532.2 - 0.0023 18.1 0.0 0.0027 17.8 0.0 1.1 1 0 0 1 1 1 1 Replication-relaxation PadR PF03551.14 ACL96532.2 - 0.016 15.1 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family GST_N PF02798.20 ACL96533.1 - 1.4e-10 41.3 0.0 2.2e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ACL96533.1 - 3.8e-10 39.6 2.8 1.5e-09 37.7 2.7 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ACL96533.1 - 2.2e-09 37.4 0.0 5.3e-09 36.2 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ACL96533.1 - 2.3e-09 37.4 0.0 3.9e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ACL96533.1 - 9.9e-09 35.3 0.1 2.1e-08 34.3 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ACL96533.1 - 1.2e-08 35.2 0.0 2.2e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Lumazine_bd_2 PF12893.7 ACL96534.1 - 3.6e-31 108.2 0.0 4e-31 108.1 0.0 1.0 1 0 0 1 1 1 1 Putative lumazine-binding DUF4440 PF14534.6 ACL96534.1 - 3.7e-07 30.5 0.1 5.2e-07 30.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_4 PF13577.6 ACL96534.1 - 1.8e-06 28.1 0.7 0.00041 20.5 0.1 2.1 2 0 0 2 2 2 2 SnoaL-like domain SnoaL_3 PF13474.6 ACL96534.1 - 0.0051 17.1 0.1 0.032 14.5 0.1 2.1 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 ACL96534.1 - 0.011 16.4 1.5 0.036 14.7 1.5 1.8 1 1 0 1 1 1 0 SnoaL-like domain DUF3225 PF11533.8 ACL96534.1 - 0.16 11.7 0.2 0.52 10.0 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3225) Tautomerase PF01361.21 ACL96535.1 - 1.3e-22 79.4 0.1 1.5e-22 79.3 0.1 1.1 1 0 0 1 1 1 1 Tautomerase enzyme Tautomerase_2 PF14552.6 ACL96535.1 - 1.2e-07 31.8 0.0 1.5e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Tautomerase enzyme Xan_ur_permease PF00860.20 ACL96535.1 - 0.16 10.7 0.0 0.17 10.5 0.0 1.0 1 0 0 1 1 1 0 Permease family Flagellin_N PF00669.20 ACL96536.1 - 1.3e-20 73.9 0.8 1.3e-20 73.9 0.8 2.9 3 0 0 3 3 3 2 Bacterial flagellin N-terminal helical region Flagellin_C PF00700.21 ACL96536.1 - 3e-06 27.5 0.4 6.5e-06 26.4 0.4 1.6 1 0 0 1 1 1 1 Bacterial flagellin C-terminal helical region TetR_C_11 PF16859.5 ACL96537.1 - 3.9e-12 46.5 13.6 1.7e-08 34.7 3.6 2.2 1 1 1 2 2 2 2 Tetracyclin repressor-like, C-terminal domain TetR_C_7 PF14246.6 ACL96537.1 - 9.2e-07 28.9 1.1 9.2e-07 28.9 1.1 1.9 2 0 0 2 2 2 1 AefR-like transcriptional repressor, C-terminal domain TetR_N PF00440.23 ACL96537.1 - 1.1e-06 28.3 0.0 2.2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family HTH_5 PF01022.20 ACL96537.1 - 0.016 15.1 0.0 0.042 13.7 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_31 PF13560.6 ACL96537.1 - 0.18 12.2 0.4 0.18 12.2 0.4 2.5 3 0 0 3 3 3 0 Helix-turn-helix domain DUF3429 PF11911.8 ACL96538.1 - 1.9e-20 73.6 21.1 2.3e-20 73.4 21.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) adh_short PF00106.25 ACL96539.1 - 4.9e-19 68.6 0.0 6.3e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ACL96539.1 - 2.2e-12 47.1 0.0 2.6e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ACL96539.1 - 8.9e-05 22.1 0.0 0.00014 21.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 ACL96539.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.4 1 1 0 1 1 1 0 KR domain NAD_binding_10 PF13460.6 ACL96539.1 - 0.054 13.4 0.0 0.09 12.7 0.0 1.4 1 1 0 1 1 1 0 NAD(P)H-binding Guanylate_cyc PF00211.20 ACL96539.1 - 0.18 11.4 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain HTH_Crp_2 PF13545.6 ACL96540.1 - 1.8e-06 27.8 0.4 0.00099 19.0 0.0 2.4 2 0 0 2 2 2 2 Crp-like helix-turn-helix domain HTH_DeoR PF08220.12 ACL96540.1 - 7.7e-06 25.6 0.0 1.8e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain HTH_24 PF13412.6 ACL96540.1 - 1.3e-05 24.6 3.7 0.00054 19.5 0.1 2.7 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 ACL96540.1 - 3.2e-05 23.6 1.7 0.038 13.8 0.1 2.7 3 0 0 3 3 3 2 IclR helix-turn-helix domain MarR_2 PF12802.7 ACL96540.1 - 0.00025 20.9 1.1 0.00025 20.9 1.1 2.4 3 1 0 3 3 3 1 MarR family MarR PF01047.22 ACL96540.1 - 0.00059 19.7 0.1 0.0064 16.4 0.0 2.4 2 0 0 2 2 2 1 MarR family GntR PF00392.21 ACL96540.1 - 0.00075 19.1 0.3 0.0019 17.8 0.3 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_20 PF12840.7 ACL96540.1 - 0.0012 18.9 0.4 0.0032 17.5 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain Rrf2 PF02082.20 ACL96540.1 - 0.0016 18.7 0.1 0.027 14.8 0.0 2.1 2 0 0 2 2 2 1 Transcriptional regulator HTH_11 PF08279.12 ACL96540.1 - 0.0017 18.3 0.0 0.004 17.1 0.0 1.6 1 0 0 1 1 1 1 HTH domain TrmB PF01978.19 ACL96540.1 - 0.0017 18.2 0.2 0.026 14.4 0.1 2.2 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB LexA_DNA_bind PF01726.16 ACL96540.1 - 0.0024 17.6 0.3 0.016 15.0 0.0 2.3 2 0 0 2 2 2 1 LexA DNA binding domain HTH_27 PF13463.6 ACL96540.1 - 0.0046 17.4 0.1 0.014 15.8 0.1 1.9 2 1 0 2 2 1 1 Winged helix DNA-binding domain HTH_23 PF13384.6 ACL96540.1 - 0.0082 15.9 0.9 0.035 13.9 0.1 2.3 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4 PF04545.16 ACL96540.1 - 0.0092 15.5 0.1 0.021 14.3 0.1 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.6 ACL96540.1 - 0.01 15.2 0.1 0.01 15.2 0.1 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_36 PF13730.6 ACL96540.1 - 0.02 14.8 0.2 0.32 11.0 0.0 2.4 3 0 0 3 3 2 0 Helix-turn-helix domain HTH_15 PF12324.8 ACL96540.1 - 0.024 14.6 0.2 0.075 13.0 0.1 1.9 1 1 1 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase HTH_28 PF13518.6 ACL96540.1 - 0.03 14.5 0.0 0.085 13.0 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain FeoC PF09012.10 ACL96540.1 - 0.035 14.2 0.0 0.07 13.2 0.0 1.5 1 0 0 1 1 1 0 FeoC like transcriptional regulator HTH_AsnC-type PF13404.6 ACL96540.1 - 0.036 13.9 0.2 0.036 13.9 0.2 2.0 2 0 0 2 2 1 0 AsnC-type helix-turn-helix domain HTH_12 PF08461.10 ACL96540.1 - 0.04 13.9 1.1 0.052 13.5 0.0 1.8 2 0 0 2 2 1 0 Ribonuclease R winged-helix domain HTH_30 PF13556.6 ACL96540.1 - 0.047 13.5 0.1 0.12 12.2 0.1 1.7 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Dimerisation2 PF16864.5 ACL96540.1 - 0.13 12.3 0.1 0.28 11.2 0.0 1.5 2 0 0 2 2 1 0 Dimerisation domain UvrB_inter PF17757.1 ACL96541.1 - 3.6e-28 97.6 0.7 3.4e-27 94.4 0.1 2.5 2 0 0 2 2 2 1 UvrB interaction domain UvrB PF12344.8 ACL96541.1 - 2.3e-21 75.3 0.2 2.3e-21 75.3 0.2 2.4 3 0 0 3 3 3 1 Ultra-violet resistance protein B Helicase_C PF00271.31 ACL96541.1 - 4.8e-19 68.7 0.2 1.4e-18 67.2 0.2 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ACL96541.1 - 1.2e-11 44.9 0.0 8e-11 42.2 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UVR PF02151.19 ACL96541.1 - 3.3e-09 36.2 7.6 1.5e-08 34.1 7.6 2.2 1 0 0 1 1 1 1 UvrB/uvrC motif DEAD PF00270.29 ACL96541.1 - 3.5e-06 26.9 0.1 1.7e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 ACL96541.1 - 0.00011 22.0 0.0 0.0012 18.6 0.0 2.6 3 0 0 3 3 3 1 AAA domain UB2H PF14814.6 ACL96541.1 - 0.00046 20.2 0.0 0.0013 18.7 0.0 1.8 1 0 0 1 1 1 1 Bifunctional transglycosylase second domain Peripla_BP_6 PF13458.6 ACL96541.1 - 0.004 16.9 0.3 1.9 8.1 0.0 2.3 2 0 0 2 2 2 2 Periplasmic binding protein Kinesin PF00225.23 ACL96541.1 - 0.0087 15.0 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ACL96541.1 - 0.02 14.8 0.0 0.12 12.4 0.0 2.3 3 0 0 3 3 3 0 Microtubule binding Flavi_DEAD PF07652.14 ACL96541.1 - 0.085 12.8 0.0 1.8 8.5 0.1 2.6 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_22 PF13401.6 ACL96541.1 - 0.11 12.8 0.0 0.69 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain VapB_antitoxin PF09957.9 ACL96543.1 - 2.3e-09 37.0 0.5 2.7e-09 36.8 0.5 1.1 1 0 0 1 1 1 1 Bacterial antitoxin of type II TA system, VapB ParE_toxin PF05016.15 ACL96544.3 - 4.2e-18 65.8 0.3 4.8e-18 65.6 0.3 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE ParD_antitoxin PF03693.14 ACL96545.2 - 1.5e-07 31.7 0.2 1.8e-07 31.5 0.2 1.1 1 0 0 1 1 1 1 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH LprI PF07007.12 ACL96546.3 - 3.2e-11 43.8 0.2 4.7e-11 43.2 0.2 1.3 1 0 0 1 1 1 1 Lysozyme inhibitor LprI T3SS_needle_F PF09392.10 ACL96546.3 - 0.022 14.9 0.0 0.045 13.9 0.0 1.5 1 0 0 1 1 1 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Tnp_DNA_bind PF14706.6 ACL96546.3 - 0.17 11.8 0.1 0.17 11.8 0.1 1.9 3 0 0 3 3 3 0 Transposase DNA-binding ACC_epsilon PF13822.6 ACL96547.2 - 0.0022 18.7 3.9 0.0038 17.9 3.9 1.4 1 0 0 1 1 1 1 Acyl-CoA carboxylase epsilon subunit HATPase_c PF02518.26 ACL96548.1 - 1e-28 100.1 0.0 1.7e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ACL96548.1 - 4.1e-20 72.0 0.0 1.8e-19 70.0 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 ACL96548.1 - 1.2e-16 60.4 0.2 2.9e-16 59.3 0.2 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain DUF588 PF04535.12 ACL96548.1 - 0.0023 17.7 5.0 0.0023 17.7 5.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF588) SBP_bac_3 PF00497.20 ACL96548.1 - 0.086 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 DUF1624 PF07786.12 ACL96549.2 - 1.4e-09 37.8 21.3 5e-09 36.0 17.9 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1624) NMO PF03060.15 ACL96550.1 - 8.3e-59 199.6 6.6 1.2e-57 195.8 6.6 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 ACL96550.1 - 3.7e-12 45.9 0.6 7.5e-07 28.5 1.1 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 ACL96550.1 - 0.00053 19.1 3.2 0.0011 18.1 3.2 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase TMP-TENI PF02581.17 ACL96550.1 - 0.0067 15.8 0.1 0.012 14.9 0.1 1.5 1 0 0 1 1 1 1 Thiamine monophosphate synthase His_biosynth PF00977.21 ACL96550.1 - 0.0072 15.8 0.3 0.018 14.5 0.3 1.6 1 1 0 1 1 1 1 Histidine biosynthesis protein Glu_synthase PF01645.17 ACL96550.1 - 0.019 14.1 3.3 0.14 11.3 3.3 2.2 1 1 0 1 1 1 0 Conserved region in glutamate synthase DUF1902 PF08972.11 ACL96550.1 - 0.045 13.8 1.0 4.3 7.4 0.1 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF1902) ThiG PF05690.14 ACL96550.1 - 0.05 12.9 1.0 0.13 11.5 1.0 1.7 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG DUF561 PF04481.12 ACL96550.1 - 0.2 10.8 0.1 0.36 9.9 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF561) LprI PF07007.12 ACL96551.2 - 2.4e-18 66.7 6.4 2.4e-18 66.7 6.4 1.8 1 1 1 2 2 2 1 Lysozyme inhibitor LprI HNOB PF07700.15 ACL96552.1 - 3.6e-36 124.6 0.0 4.1e-36 124.4 0.0 1.0 1 0 0 1 1 1 1 Haem-NO-binding V4R PF02830.18 ACL96552.1 - 0.00019 21.4 1.8 0.00019 21.4 1.8 1.7 2 0 0 2 2 2 1 V4R domain Glyco_hydro_130 PF04041.13 ACL96552.1 - 0.19 10.6 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 beta-1,4-mannooligosaccharide phosphorylase HATPase_c PF02518.26 ACL96553.1 - 1.9e-24 86.3 0.0 3.3e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ACL96553.1 - 6.1e-23 81.1 0.0 1.2e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ACL96553.1 - 7.4e-14 51.5 0.3 7.4e-14 51.5 0.3 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 ACL96553.1 - 3.3e-13 50.1 1.5 1.1e-12 48.5 1.0 2.2 2 0 0 2 2 2 1 GAF domain HATPase_c_3 PF13589.6 ACL96553.1 - 0.00075 19.3 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HPTransfase PF10090.9 ACL96553.1 - 0.0021 17.8 0.2 2.1 8.2 0.0 3.0 2 0 0 2 2 2 2 Histidine phosphotransferase C-terminal domain GAF PF01590.26 ACL96553.1 - 0.0024 18.5 0.1 0.0068 17.0 0.1 1.8 1 0 0 1 1 1 1 GAF domain HATPase_c_2 PF13581.6 ACL96553.1 - 0.013 15.4 0.7 0.25 11.3 0.0 2.8 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain LprI PF07007.12 ACL96554.1 - 1.2e-19 70.8 1.1 1.6e-19 70.4 1.1 1.2 1 0 0 1 1 1 1 Lysozyme inhibitor LprI ACCA PF03255.14 ACL96555.1 - 6.9e-60 201.1 0.1 1.6e-59 199.9 0.1 1.6 1 0 0 1 1 1 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Carboxyl_trans PF01039.22 ACL96555.1 - 3.7e-18 65.4 0.7 4.4e-18 65.2 0.7 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain ABC_tran_CTD PF16326.5 ACL96555.1 - 0.19 12.0 2.7 0.19 12.0 0.7 2.0 3 0 0 3 3 3 0 ABC transporter C-terminal domain p450 PF00067.22 ACL96557.1 - 3.7e-68 230.4 0.0 4.8e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 OsmC PF02566.19 ACL96558.2 - 4.2e-18 65.7 0.0 5.5e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 OsmC-like protein HpcH_HpaI PF03328.14 ACL96559.2 - 3.5e-24 85.2 0.0 9e-24 83.8 0.0 1.7 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 ACL96559.2 - 0.0028 16.9 0.0 0.32 10.1 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold MS_channel PF00924.18 ACL96560.1 - 5e-43 147.1 0.0 6.6e-43 146.7 0.0 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel MscS_TM PF12794.7 ACL96560.1 - 7.5 5.3 9.9 0.099 11.5 2.1 1.7 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 TonB_dep_Rec PF00593.24 ACL96561.1 - 1.7e-25 90.8 30.6 1.7e-25 90.8 30.6 2.2 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 ACL96561.1 - 2.6e-16 60.1 0.9 6.7e-16 58.8 0.9 1.8 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain Aldo_ket_red PF00248.21 ACL96562.1 - 5.5e-73 245.7 0.0 6.2e-73 245.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Asp_protease_2 PF13650.6 ACL96563.1 - 0.00032 21.3 0.0 0.0069 17.0 0.0 2.5 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 ACL96563.1 - 0.059 13.9 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Lebercilin PF15619.6 ACL96564.1 - 0.26 10.9 12.1 0.21 11.2 2.2 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease V-SNARE PF05008.15 ACL96564.1 - 0.53 10.7 10.9 0.25 11.8 0.4 3.3 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus PSII_Pbs27 PF13326.6 ACL96564.1 - 5.5 7.3 14.7 0.98 9.7 0.5 2.3 1 1 1 2 2 2 0 Photosystem II Pbs27 PhnA PF03831.14 ACL96565.1 - 5.5e-28 96.6 3.4 6.1e-28 96.5 3.4 1.0 1 0 0 1 1 1 1 PhnA domain Phage_integrase PF00589.22 ACL96566.1 - 6e-43 146.6 0.0 8.7e-43 146.1 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 ACL96566.1 - 2.3e-17 63.0 0.5 1.5e-16 60.4 0.1 2.5 2 1 1 3 3 3 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 ACL96566.1 - 4e-07 30.4 0.0 3.1e-06 27.6 0.0 2.2 1 1 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_integr_3 PF16795.5 ACL96566.1 - 0.00014 21.8 0.0 0.024 14.6 0.0 2.2 1 1 1 2 2 2 2 Archaeal phage integrase TPR_19 PF14559.6 ACL96567.3 - 0.00019 21.9 3.0 0.00019 21.9 3.0 5.2 4 2 0 5 5 5 1 Tetratricopeptide repeat SKI PF01202.22 ACL96568.1 - 1.8e-45 154.9 0.0 2.2e-45 154.6 0.0 1.0 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 ACL96568.1 - 7.4e-06 26.5 0.1 2.5e-05 24.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 ACL96568.1 - 8.2e-06 26.1 0.2 0.02 15.1 0.0 2.1 1 1 1 2 2 2 2 Cytidylate kinase-like family AAA_33 PF13671.6 ACL96568.1 - 0.0017 18.5 0.2 0.0086 16.2 0.2 1.9 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ACL96568.1 - 0.039 13.9 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase dNK PF01712.19 ACL96568.1 - 0.058 13.2 0.0 0.62 9.9 0.0 2.0 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_22 PF13401.6 ACL96568.1 - 0.071 13.4 0.0 0.15 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ACL96568.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.29 ACL96568.1 - 0.13 12.7 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ACL96568.1 - 0.13 12.6 0.4 0.23 11.9 0.4 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 ACL96568.1 - 0.17 11.6 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain DHQ_synthase PF01761.20 ACL96569.1 - 1.9e-100 335.4 0.0 2.3e-100 335.1 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 ACL96569.1 - 9.7e-18 64.8 0.9 1.2e-16 61.2 0.9 2.0 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 ACL96569.1 - 2.8e-13 49.4 5.1 3.8e-11 42.4 1.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase DnaJ PF00226.31 ACL96570.1 - 2.8e-10 40.2 0.1 7.1e-10 38.9 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain BolA PF01722.18 ACL96571.2 - 2e-26 92.1 0.3 2.3e-26 91.9 0.3 1.0 1 0 0 1 1 1 1 BolA-like protein dCMP_cyt_deam_1 PF00383.23 ACL96572.2 - 2.8e-12 46.4 0.7 3.7e-12 46.0 0.7 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 ACL96572.2 - 8.4e-09 35.7 4.6 2.1e-07 31.2 1.3 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region Fer2_BFD PF04324.15 ACL96572.2 - 0.073 13.4 1.1 0.18 12.2 1.1 1.7 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain LmjF365940-deam PF14421.6 ACL96572.2 - 0.11 12.1 1.9 0.68 9.5 1.9 1.9 1 1 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases TonB_dep_Rec PF00593.24 ACL96573.2 - 2.4e-38 133.2 21.7 2.4e-38 133.2 21.7 2.5 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 ACL96573.2 - 4.4e-14 52.9 2.8 9.4e-14 51.9 2.8 1.6 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain Response_reg PF00072.24 ACL96575.1 - 1.5e-09 38.0 0.0 2.2e-09 37.5 0.0 1.3 1 1 0 1 1 1 1 Response regulator receiver domain DUF21 PF01595.20 ACL96577.1 - 1.8e-42 145.0 1.9 2.4e-42 144.6 1.9 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 ACL96577.1 - 4.6e-17 61.8 0.9 1.7e-16 60.0 0.0 2.2 2 0 0 2 2 2 1 Transporter associated domain CBS PF00571.28 ACL96577.1 - 7.5e-12 45.5 4.3 1.9e-05 25.0 0.0 3.7 4 0 0 4 4 4 2 CBS domain PAP2 PF01569.21 ACL96578.2 - 4.3e-23 81.6 4.8 4.3e-23 81.6 4.8 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 ACL96578.2 - 3.1e-07 30.3 8.9 3.1e-07 30.3 8.9 1.9 2 1 0 2 2 2 1 PAP2 superfamily CBP_BcsF PF11120.8 ACL96578.2 - 0.17 12.0 3.4 0.54 10.4 0.2 2.6 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsF DUF962 PF06127.11 ACL96578.2 - 0.21 11.7 2.2 6.6 6.9 0.6 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF962) PAP2_C PF14360.6 ACL96578.2 - 1.2 9.7 5.8 0.45 11.1 2.0 2.1 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Caps_synth_GfcC PF06251.11 ACL96579.1 - 0.12 11.9 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Capsule biosynthesis GfcC CobS_N PF12556.8 ACL96580.1 - 1.6e-15 56.5 0.3 3.3e-15 55.5 0.3 1.6 1 0 0 1 1 1 1 Cobaltochelatase CobS subunit N terminal AAA_5 PF07728.14 ACL96580.1 - 6.2e-12 45.7 0.0 1e-11 45.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) CbbQ_C PF08406.10 ACL96580.1 - 0.00034 20.8 0.0 0.00058 20.1 0.0 1.4 1 0 0 1 1 1 1 CbbQ/NirQ/NorQ C-terminal AAA PF00004.29 ACL96580.1 - 0.00047 20.6 0.0 0.0014 19.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 ACL96580.1 - 0.0026 17.6 0.0 0.005 16.7 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 ACL96580.1 - 0.0073 16.5 0.0 0.014 15.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ACL96580.1 - 0.011 16.3 0.0 0.018 15.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ACL96580.1 - 0.029 14.8 0.0 0.18 12.2 0.0 2.0 1 1 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.6 ACL96580.1 - 0.083 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Bactofilin PF04519.13 ACL96582.2 - 1.2e-21 76.9 2.7 1.5e-21 76.5 2.7 1.1 1 0 0 1 1 1 1 Polymer-forming cytoskeletal CW_7 PF08230.11 ACL96583.1 - 1.2 8.9 4.1 1.9 8.3 0.7 2.5 2 1 0 2 2 2 0 CW_7 repeat CheW PF01584.19 ACL96585.1 - 2.5e-35 121.1 0.6 2.9e-35 120.9 0.6 1.0 1 0 0 1 1 1 1 CheW-like domain SdpI PF13630.6 ACL96587.1 - 1.4e-14 53.9 0.1 1.4e-14 53.9 0.1 3.1 2 1 0 2 2 2 1 SdpI/YhfL protein family DUF1648 PF07853.11 ACL96587.1 - 5.8e-07 29.1 2.2 1.3e-06 28.0 0.1 2.7 2 2 0 2 2 2 1 Protein of unknown function (DUF1648) TctB PF07331.11 ACL96587.1 - 3.5 7.9 17.2 2.1 8.6 11.4 2.2 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family HTH_20 PF12840.7 ACL96588.2 - 7.4e-15 54.8 0.0 1.3e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_5 PF01022.20 ACL96588.2 - 4.8e-13 48.7 0.0 8.3e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 ACL96588.2 - 3.9e-07 29.9 0.0 6.1e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 MarR family MarR PF01047.22 ACL96588.2 - 0.00025 20.9 0.0 0.00037 20.4 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_IclR PF09339.10 ACL96588.2 - 0.00026 20.7 0.0 0.00039 20.1 0.0 1.4 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_24 PF13412.6 ACL96588.2 - 0.0012 18.4 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 ACL96588.2 - 0.0012 18.7 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Rrf2 PF02082.20 ACL96588.2 - 0.0014 18.9 0.0 0.002 18.5 0.0 1.4 1 1 0 1 1 1 1 Transcriptional regulator GntR PF00392.21 ACL96588.2 - 0.0018 17.9 0.0 0.003 17.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_11 PF08279.12 ACL96588.2 - 0.0018 18.2 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 HTH domain TrmB PF01978.19 ACL96588.2 - 0.0035 17.2 0.0 0.006 16.4 0.0 1.4 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Penicillinase_R PF03965.16 ACL96588.2 - 0.0058 17.0 0.0 0.0062 16.9 0.0 1.2 1 0 0 1 1 1 1 Penicillinase repressor HTH_40 PF14493.6 ACL96588.2 - 0.029 14.8 0.0 0.035 14.6 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain DUF742 PF05331.11 ACL96588.2 - 0.031 14.1 0.1 0.037 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF742) Sigma70_r4_2 PF08281.12 ACL96588.2 - 0.039 13.6 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 RP-C PF03428.13 ACL96588.2 - 0.047 13.4 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 Replication protein C N-terminal domain PaaX PF07848.12 ACL96588.2 - 0.049 13.9 0.0 0.077 13.2 0.0 1.3 1 0 0 1 1 1 0 PaaX-like protein Fe_dep_repress PF01325.19 ACL96588.2 - 0.059 13.6 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Sigma70_r4 PF04545.16 ACL96588.2 - 0.09 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.6 ACL96588.2 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 ADH_N PF08240.12 ACL96589.1 - 5.5e-28 97.0 1.1 1.2e-27 95.9 1.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ACL96589.1 - 3.4e-27 95.0 1.0 6.6e-27 94.1 1.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ACL96589.1 - 1.6e-08 35.6 0.0 5.3e-08 34.0 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 ACL96589.1 - 0.1 11.9 0.5 0.19 11.1 0.5 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MFS_2 PF13347.6 ACL96590.1 - 2.5e-65 220.7 23.4 2.8e-65 220.6 23.4 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 ACL96590.1 - 1e-20 74.0 53.0 3.9e-12 45.8 25.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2937 PF11157.8 ACL96590.1 - 1.6 8.5 6.6 0.22 11.2 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2937) OATP PF03137.20 ACL96590.1 - 2.8 6.1 8.5 1 7.5 4.4 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Phosphoesterase PF04185.14 ACL96591.1 - 4.1e-137 457.1 0.0 5.2e-137 456.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoesterase family DUF756 PF05506.12 ACL96591.1 - 6.7e-29 100.6 0.7 4.6e-22 78.7 0.3 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF756) Peptidase_M20 PF01546.28 ACL96592.2 - 3e-19 69.6 0.2 5.2e-19 68.8 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ACL96592.2 - 6.1e-10 39.0 0.0 1.2e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 ACL96592.2 - 7.8e-08 32.2 0.0 2.4e-07 30.6 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 PepSY_2 PF13670.6 ACL96592.2 - 6.1 6.9 9.4 3.4 7.7 4.5 2.9 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain EamA PF00892.20 ACL96593.1 - 8.4e-32 110.2 35.7 6.4e-16 58.8 15.8 2.1 2 0 0 2 2 2 2 EamA-like transporter family TMEM234 PF10639.9 ACL96593.1 - 4.7e-05 23.4 4.4 0.25 11.4 0.5 3.2 2 1 0 2 2 2 2 Putative transmembrane family 234 TPT PF03151.16 ACL96593.1 - 0.00035 20.0 4.6 0.005 16.2 0.6 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family Peptidase_M23 PF01551.22 ACL96594.1 - 4e-30 103.9 0.3 4e-30 103.9 0.3 2.1 3 0 0 3 3 3 1 Peptidase family M23 Response_reg PF00072.24 ACL96595.1 - 2.9e-26 91.8 0.3 4.5e-26 91.2 0.3 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 ACL96595.1 - 2.7e-20 72.2 0.0 5.1e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal LytTR PF04397.15 ACL96596.1 - 6.7e-16 58.3 0.0 8.9e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 LytTr DNA-binding domain FG-GAP_2 PF14312.6 ACL96596.1 - 0.071 13.4 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 FG-GAP repeat HTH_3 PF01381.22 ACL96597.1 - 0.00011 22.2 0.0 0.0002 21.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix Phage_AlpA PF05930.12 ACL96597.1 - 0.035 13.9 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) HTH_26 PF13443.6 ACL96597.1 - 0.17 12.4 0.0 0.25 11.8 0.0 1.2 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Gp49 PF05973.14 ACL96598.1 - 4.2e-05 23.6 0.0 5.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Phage derived protein Gp49-like (DUF891) Abhydrolase_1 PF00561.20 ACL96599.1 - 1.2e-07 31.7 0.0 0.00075 19.2 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold PAF-AH_p_II PF03403.13 ACL96599.1 - 1.5e-06 27.0 0.3 0.0001 20.9 0.2 2.1 1 1 1 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II DLH PF01738.18 ACL96599.1 - 8.6e-05 22.2 0.1 0.0088 15.6 0.1 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 ACL96599.1 - 0.00011 21.7 0.1 0.0003 20.3 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 ACL96599.1 - 0.00012 21.5 2.2 0.0059 15.9 0.6 2.7 1 1 2 3 3 3 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 ACL96599.1 - 0.0012 18.5 0.5 0.0017 18.0 0.1 1.5 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 ACL96599.1 - 0.0017 18.4 0.0 0.015 15.2 0.0 2.3 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal ATP-synt_ab PF00006.25 ACL96600.1 - 9.2e-68 228.1 0.0 1.2e-67 227.7 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain T3SS_ATPase_C PF18269.1 ACL96600.1 - 2e-21 75.6 0.1 4.6e-21 74.4 0.0 1.6 2 0 0 2 2 2 1 T3SS EscN ATPase C-terminal domain ATP-synt_ab_N PF02874.23 ACL96600.1 - 2.1e-07 31.4 0.5 7.6e-07 29.6 0.5 2.0 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ABC_tran PF00005.27 ACL96600.1 - 0.017 15.6 0.0 0.027 15.0 0.0 1.3 1 0 0 1 1 1 0 ABC transporter FliJ PF02050.16 ACL96601.1 - 0.0017 18.6 12.2 0.0045 17.2 12.2 1.7 1 1 0 1 1 1 1 Flagellar FliJ protein DivIC PF04977.15 ACL96601.1 - 0.097 12.5 8.4 0.38 10.5 1.3 2.4 2 0 0 2 2 2 0 Septum formation initiator Glyco_hydro_10 PF00331.20 ACL96602.1 - 6.4e-80 268.7 0.0 7.7e-80 268.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 peroxidase PF00141.23 ACL96603.1 - 5.2e-88 294.6 0.0 7e-49 166.6 0.0 2.2 2 0 0 2 2 2 2 Peroxidase ILVD_EDD PF00920.21 ACL96604.1 - 2.5e-217 722.6 4.4 2.8e-217 722.4 4.4 1.0 1 0 0 1 1 1 1 Dehydratase family LysR_substrate PF03466.20 ACL96605.1 - 6.1e-37 127.0 9.7 6.2e-37 127.0 7.2 1.9 2 0 0 2 2 2 1 LysR substrate binding domain HTH_1 PF00126.27 ACL96605.1 - 1.7e-21 75.9 1.5 3.4e-21 74.9 1.5 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_24 PF13412.6 ACL96605.1 - 0.068 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding ACT_6 PF13740.6 ACL96606.1 - 1.2e-15 57.2 2.0 3.4e-09 36.6 0.2 2.4 3 0 0 3 3 3 2 ACT domain ACT PF01842.25 ACL96606.1 - 5.4e-07 29.3 0.2 2.1e-05 24.2 0.0 2.5 2 0 0 2 2 2 1 ACT domain ACT_4 PF13291.6 ACL96606.1 - 2.1e-06 28.2 0.0 0.0019 18.7 0.0 2.4 2 1 0 2 2 2 2 ACT domain ACT_7 PF13840.6 ACL96606.1 - 0.11 12.4 0.1 0.65 9.8 0.0 2.1 2 0 0 2 2 2 0 ACT domain Sigma70_ner PF04546.13 ACL96607.2 - 6.7e-40 137.2 0.0 6.7e-40 137.2 0.0 2.4 3 0 0 3 3 3 1 Sigma-70, non-essential region Sigma70_r3 PF04539.16 ACL96607.2 - 8.8e-31 105.8 2.7 1.9e-29 101.6 0.6 3.2 3 0 0 3 3 3 1 Sigma-70 region 3 Sigma70_r2 PF04542.14 ACL96607.2 - 6.1e-22 77.2 0.8 2e-21 75.5 0.3 2.2 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r1_1 PF03979.14 ACL96607.2 - 6.9e-21 74.1 0.7 6.9e-21 74.1 0.7 2.4 3 0 0 3 3 2 1 Sigma-70 factor, region 1.1 Sigma70_r4 PF04545.16 ACL96607.2 - 2.7e-20 71.6 6.4 1.7e-18 65.9 1.1 3.3 3 0 0 3 3 3 2 Sigma-70, region 4 Sigma70_r1_2 PF00140.20 ACL96607.2 - 7.8e-14 51.4 2.8 1.7e-13 50.4 0.2 2.7 3 0 0 3 3 3 1 Sigma-70 factor, region 1.2 HTH_15 PF12324.8 ACL96607.2 - 0.00088 19.2 0.8 1.5 8.9 0.0 3.9 3 0 0 3 3 3 1 Helix-turn-helix domain of alkylmercury lyase Sec8_exocyst PF04048.14 ACL96607.2 - 0.04 13.8 0.1 6.3 6.7 0.1 2.9 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain MarR_2 PF12802.7 ACL96607.2 - 0.05 13.5 0.1 5.6 6.9 0.0 3.3 3 0 0 3 3 3 0 MarR family LRR_9 PF14580.6 ACL96607.2 - 0.056 13.0 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 Leucine-rich repeat RraB PF06877.11 ACL96607.2 - 0.23 12.2 1.4 10 6.9 0.0 3.7 4 0 0 4 4 3 0 Regulator of ribonuclease activity B HTH_25 PF13413.6 ACL96607.2 - 6.8 6.6 7.1 20 5.1 0.0 3.7 4 0 0 4 4 4 0 Helix-turn-helix domain PAS_3 PF08447.12 ACL96608.1 - 2.5e-31 107.8 0.1 1.4e-13 50.9 0.2 3.4 3 0 0 3 3 3 3 PAS fold HWE_HK PF07536.14 ACL96608.1 - 1.6e-28 99.2 0.0 4.7e-28 97.7 0.0 1.9 1 0 0 1 1 1 1 HWE histidine kinase PAS PF00989.25 ACL96608.1 - 1.9e-28 98.7 0.0 3.3e-10 39.9 0.0 3.3 3 0 0 3 3 3 3 PAS fold PAS_4 PF08448.10 ACL96608.1 - 1.6e-25 89.5 4.1 5.6e-10 39.5 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.7 ACL96608.1 - 1.3e-19 70.4 0.0 8e-06 26.1 0.0 3.3 3 0 0 3 3 3 3 PAS domain PAS_8 PF13188.7 ACL96608.1 - 2.1e-07 30.8 0.2 0.041 13.9 0.0 3.1 3 0 0 3 3 3 2 PAS domain HisKA_2 PF07568.12 ACL96608.1 - 1.9e-06 27.8 0.2 4.9e-06 26.6 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase HATPase_c_2 PF13581.6 ACL96608.1 - 0.0029 17.6 0.0 0.0085 16.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain dCache_1 PF02743.18 ACL96608.1 - 0.021 14.6 0.2 1.8 8.3 0.0 2.3 1 1 1 2 2 2 0 Cache domain Toprim_N PF08275.11 ACL96609.1 - 1.5e-38 131.7 0.0 2.4e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 DNA primase catalytic core, N-terminal domain zf-CHC2 PF01807.20 ACL96609.1 - 4.5e-29 100.2 0.0 8e-29 99.3 0.0 1.4 1 0 0 1 1 1 1 CHC2 zinc finger Toprim_2 PF13155.6 ACL96609.1 - 1.2e-13 51.2 0.0 6e-13 49.0 0.0 2.3 2 0 0 2 2 2 1 Toprim-like Toprim_4 PF13662.6 ACL96609.1 - 2.1e-11 44.1 0.0 5.4e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Toprim domain Toprim_3 PF13362.6 ACL96609.1 - 2.4e-07 31.0 0.9 1.2e-06 28.7 0.0 2.8 4 0 0 4 4 4 1 Toprim domain Toprim PF01751.22 ACL96609.1 - 0.02 15.1 0.0 0.065 13.5 0.0 1.9 1 1 0 1 1 1 0 Toprim domain RHH_1 PF01402.21 ACL96609.1 - 1.5 8.9 5.4 23 5.1 1.7 3.0 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Peptidase_M61_N PF17899.1 ACL96611.1 - 1.3e-38 132.7 0.0 2e-38 132.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase M61 N-terminal domain Peptidase_M61 PF05299.12 ACL96611.1 - 3.8e-37 127.3 0.1 6.8e-37 126.5 0.1 1.3 1 0 0 1 1 1 1 M61 glycyl aminopeptidase PDZ_6 PF17820.1 ACL96611.1 - 8e-05 22.4 0.1 0.00025 20.8 0.1 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 ACL96611.1 - 0.00022 21.5 0.0 0.0021 18.3 0.0 2.3 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 ACL96611.1 - 0.025 14.9 0.0 0.053 13.9 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Peptidase_M9 PF01752.17 ACL96611.1 - 0.13 11.5 0.3 0.22 10.7 0.3 1.4 1 0 0 1 1 1 0 Collagenase FTCD_C PF04961.12 ACL96611.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase DUF885 PF05960.11 ACL96613.1 - 1.8e-156 522.9 5.3 2.1e-156 522.7 5.3 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) Pou PF00157.17 ACL96613.1 - 0.0068 16.3 0.0 0.021 14.8 0.0 1.8 2 0 0 2 2 2 1 Pou domain - N-terminal to homeobox domain Glyco_hydro_3 PF00933.21 ACL96614.1 - 2.1e-73 247.5 0.2 7.7e-73 245.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 ACL96614.1 - 5.6e-57 193.0 0.0 1.2e-56 191.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 ACL96614.1 - 2.3e-23 82.1 1.4 1.3e-22 79.7 0.0 2.6 3 0 0 3 3 3 1 Fibronectin type III-like domain CARDB PF07705.11 ACL96614.1 - 0.0051 17.0 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 CARDB DUF11 PF01345.18 ACL96614.1 - 0.25 11.7 1.3 1.4 9.2 1.3 2.2 1 1 0 1 1 1 0 Domain of unknown function DUF11 SASA PF03629.18 ACL96616.1 - 4.6e-16 59.2 0.0 4.2e-08 33.1 0.1 2.3 2 0 0 2 2 2 2 Carbohydrate esterase, sialic acid-specific acetylesterase Big_6 PF17936.1 ACL96616.1 - 0.0027 18.0 0.3 0.0087 16.3 0.3 1.9 1 0 0 1 1 1 1 Bacterial Ig domain Glyco_hydro_2_N PF02837.18 ACL96616.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain CarboxypepD_reg PF13620.6 ACL96616.1 - 0.038 14.2 1.0 0.39 11.0 0.2 3.0 3 0 0 3 3 3 0 Carboxypeptidase regulatory-like domain CBM-like PF14683.6 ACL96616.1 - 0.13 12.2 0.1 11 5.9 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide lyase family 4, domain III Protoglobin PF11563.8 ACL96617.1 - 0.00028 20.8 0.0 0.00041 20.3 0.0 1.2 1 0 0 1 1 1 1 Protoglobin Bac_globin PF01152.21 ACL96617.1 - 0.12 12.5 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial-like globin 2OG-Fe_Oxy_2 PF10014.9 ACL96618.1 - 7e-68 228.2 0.0 8.1e-68 228.0 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe dioxygenase HWE_HK PF07536.14 ACL96619.1 - 1.9e-24 86.2 0.0 4.3e-24 85.0 0.0 1.7 1 0 0 1 1 1 1 HWE histidine kinase PAS_4 PF08448.10 ACL96619.1 - 2e-22 79.5 2.3 4.2e-22 78.5 0.4 2.5 4 0 0 4 4 4 1 PAS fold Response_reg PF00072.24 ACL96619.1 - 8.6e-09 35.6 0.0 1.4e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain PAS_10 PF13596.6 ACL96619.1 - 7.4e-07 29.7 0.0 1.9e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 PAS domain HisKA_2 PF07568.12 ACL96619.1 - 1e-05 25.5 0.0 2.3e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase PAS PF00989.25 ACL96619.1 - 1.1e-05 25.4 0.0 2.2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 ACL96619.1 - 0.00027 20.9 0.0 0.00072 19.5 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 ACL96619.1 - 0.00055 20.1 0.0 0.00094 19.4 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_7 PF12860.7 ACL96619.1 - 0.003 17.7 0.0 0.0072 16.5 0.0 1.7 1 1 0 1 1 1 1 PAS fold HATPase_c_2 PF13581.6 ACL96619.1 - 0.1 12.5 0.0 0.27 11.2 0.0 1.7 1 1 0 1 1 1 0 Histidine kinase-like ATPase domain PepSY_TM_like_2 PF16357.5 ACL96620.1 - 1.8e-84 282.7 0.2 2e-84 282.5 0.2 1.0 1 0 0 1 1 1 1 Putative PepSY_TM-like PepSY_TM PF03929.16 ACL96620.1 - 8.3e-11 42.1 5.8 2.1e-10 40.7 3.0 2.1 1 1 0 1 1 1 1 PepSY-associated TM region DUF2271 PF10029.9 ACL96621.1 - 2.8e-49 166.2 0.1 3.3e-49 166.0 0.1 1.0 1 0 0 1 1 1 1 Predicted periplasmic protein (DUF2271) DUF4198 PF10670.9 ACL96622.1 - 1.7e-65 221.4 2.0 1.9e-65 221.2 2.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4198) CarboxypepD_reg PF13620.6 ACL96622.1 - 0.017 15.4 0.5 0.58 10.5 0.0 2.5 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain PPC PF04151.15 ACL96622.1 - 0.13 13.4 0.4 28 5.9 0.2 2.5 2 0 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain ApbE PF02424.15 ACL96623.2 - 9.9e-81 271.1 0.0 1.2e-80 270.8 0.0 1.0 1 0 0 1 1 1 1 ApbE family Flavodoxin_1 PF00258.25 ACL96624.1 - 1.7e-24 86.7 0.0 2.8e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 ACL96624.1 - 7.5e-09 36.2 0.0 1.8e-08 35.0 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.20 ACL96624.1 - 7.6e-05 22.4 0.0 0.48 10.0 0.0 2.5 2 1 1 3 3 3 2 FAD binding domain Flavodoxin_5 PF12724.7 ACL96624.1 - 0.066 13.5 0.0 0.28 11.4 0.0 1.9 1 1 1 2 2 2 0 Flavodoxin domain NTP_transf_3 PF12804.7 ACL96625.1 - 4.1e-21 76.0 7.6 4.9e-21 75.8 7.6 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Peripla_BP_3 PF13377.6 ACL96626.1 - 4.3e-39 134.5 0.3 8.3e-39 133.6 0.3 1.5 1 0 0 1 1 1 1 Periplasmic binding protein-like domain Peripla_BP_1 PF00532.21 ACL96626.1 - 1.2e-24 87.3 0.0 1.9e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family LacI PF00356.21 ACL96626.1 - 7.7e-20 70.4 0.8 1.8e-19 69.3 0.8 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family Peripla_BP_4 PF13407.6 ACL96626.1 - 1.8e-14 54.0 0.0 2.6e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain HTH_23 PF13384.6 ACL96626.1 - 0.0016 18.2 0.9 0.0041 16.9 0.4 1.9 2 0 0 2 2 1 1 Homeodomain-like domain HTH_3 PF01381.22 ACL96626.1 - 0.0031 17.5 0.3 0.0076 16.3 0.3 1.7 1 0 0 1 1 1 1 Helix-turn-helix HTH_Tnp_ISL3 PF13542.6 ACL96626.1 - 0.0066 15.8 0.8 0.0066 15.8 0.8 2.1 3 0 0 3 3 3 1 Helix-turn-helix domain of transposase family ISL3 HTH_31 PF13560.6 ACL96626.1 - 0.012 16.0 3.7 0.013 15.8 1.6 2.2 2 0 0 2 2 1 0 Helix-turn-helix domain HTH_38 PF13936.6 ACL96626.1 - 0.018 14.8 2.5 0.02 14.6 1.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_24 PF13412.6 ACL96626.1 - 0.035 13.7 0.1 0.11 12.1 0.1 1.9 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_AraC PF00165.23 ACL96626.1 - 0.036 14.2 0.0 0.073 13.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family TetR_N PF00440.23 ACL96626.1 - 0.079 12.8 1.9 0.22 11.4 0.1 2.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family AbiEi_4 PF13338.6 ACL96626.1 - 0.098 12.8 0.4 0.57 10.4 0.2 2.4 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin TnsD PF15978.5 ACL96626.1 - 0.12 11.3 0.1 0.17 10.8 0.1 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D MarR_2 PF12802.7 ACL96626.1 - 0.14 12.1 2.3 0.26 11.2 0.6 2.4 2 0 0 2 2 2 0 MarR family HTH_Crp_2 PF13545.6 ACL96626.1 - 0.2 11.7 0.6 0.64 10.0 0.2 2.1 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Sigma70_r4 PF04545.16 ACL96626.1 - 0.26 10.8 1.4 0.54 9.8 0.2 2.1 3 0 0 3 3 3 0 Sigma-70, region 4 ArgJ PF01960.18 ACL96627.3 - 2.5e-135 451.0 3.8 3e-135 450.8 3.8 1.0 1 0 0 1 1 1 1 ArgJ family Rotamase_3 PF13616.6 ACL96628.1 - 3.5e-14 53.3 0.0 6.2e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 ACL96628.1 - 4.5e-14 53.2 0.0 1e-13 52.0 0.0 1.7 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 ACL96628.1 - 1.7e-13 51.5 0.4 1.7e-13 51.5 0.4 1.8 2 0 0 2 2 2 1 PPIC-type PPIASE domain SurA_N_3 PF13624.6 ACL96628.1 - 1.4e-05 24.9 0.2 6.2e-05 22.8 0.0 2.0 1 1 1 2 2 2 1 SurA N-terminal domain DUF2939 PF11159.8 ACL96628.1 - 0.014 15.8 0.2 0.04 14.3 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) SecA_DEAD PF07517.14 ACL96629.1 - 1.2e-130 435.0 2.2 2.1e-130 434.2 2.2 1.4 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_SW PF07516.13 ACL96629.1 - 3.6e-63 213.2 5.0 2e-62 210.8 4.6 2.3 2 0 0 2 2 2 1 SecA Wing and Scaffold domain SecA_PP_bind PF01043.20 ACL96629.1 - 1.4e-35 122.3 2.5 2.1e-35 121.7 0.7 2.3 2 0 0 2 2 2 1 SecA preprotein cross-linking domain SEC-C PF02810.15 ACL96629.1 - 7.7e-10 38.5 6.7 1.3e-09 37.8 6.7 1.4 1 0 0 1 1 1 1 SEC-C motif DEAD PF00270.29 ACL96629.1 - 0.0016 18.2 0.0 0.0051 16.6 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase MFS_1 PF07690.16 ACL96630.1 - 1.3e-49 169.1 44.3 1.3e-49 169.1 44.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ACL96630.1 - 2.4e-05 23.4 22.7 0.0005 19.0 8.7 3.2 3 1 0 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.6 ACL96630.1 - 0.013 14.1 21.1 0.15 10.6 8.9 3.1 1 1 1 2 2 2 0 MFS/sugar transport protein HTH_20 PF12840.7 ACL96631.1 - 3.8e-13 49.3 1.2 1.2e-12 47.7 0.3 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_27 PF13463.6 ACL96631.1 - 3.4e-06 27.5 0.1 0.32 11.5 0.0 3.2 3 0 0 3 3 3 2 Winged helix DNA-binding domain MarR_2 PF12802.7 ACL96631.1 - 8.6e-05 22.3 2.1 0.001 18.9 0.5 2.5 2 0 0 2 2 2 1 MarR family HTH_5 PF01022.20 ACL96631.1 - 0.0012 18.7 0.0 0.0035 17.2 0.0 1.8 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family PaaX PF07848.12 ACL96631.1 - 0.0021 18.2 1.8 0.14 12.4 0.2 3.2 3 0 0 3 3 3 1 PaaX-like protein MarR PF01047.22 ACL96631.1 - 0.066 13.2 0.0 0.29 11.1 0.0 2.1 3 0 0 3 3 3 0 MarR family HTH_AsnC-type PF13404.6 ACL96631.1 - 0.077 12.8 0.7 1.1 9.1 0.2 3.0 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain DEC-1_N PF04625.13 ACL96632.1 - 1.9 7.4 6.1 2.5 7.0 6.1 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region SH3_3 PF08239.11 ACL96634.2 - 3.1e-11 43.4 0.3 5.1e-11 42.7 0.3 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain Gly-zipper_Omp PF13488.6 ACL96634.2 - 5.8e-10 39.0 13.1 5.8e-10 39.0 13.1 2.8 2 1 0 2 2 2 1 Glycine zipper Rick_17kDa_Anti PF05433.15 ACL96634.2 - 9e-10 38.3 38.5 2.9e-08 33.4 19.6 3.1 2 1 1 3 3 3 2 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.6 ACL96634.2 - 2.6e-06 27.1 19.3 2.6e-06 27.1 19.3 2.7 2 1 1 3 3 3 2 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.6 ACL96634.2 - 0.0015 18.3 17.6 0.0015 18.3 17.6 2.7 2 1 0 2 2 2 1 Glycine-zipper domain CPBP PF02517.16 ACL96635.1 - 1.9e-11 44.2 1.3 1.9e-11 44.2 1.3 2.0 1 1 1 2 2 2 1 CPBP intramembrane metalloprotease Response_reg PF00072.24 ACL96636.1 - 4.6e-28 97.6 0.2 8.9e-28 96.7 0.2 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 ACL96636.1 - 9.5e-28 97.0 0.1 1.5e-27 96.3 0.1 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ACL96636.1 - 7.1e-20 70.8 0.5 7.1e-20 70.8 0.5 2.8 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain TPR_9 PF13371.6 ACL96636.1 - 0.0078 16.3 0.5 0.0078 16.3 0.5 4.2 4 1 1 5 5 5 1 Tetratricopeptide repeat HATPase_c_3 PF13589.6 ACL96636.1 - 0.0084 15.9 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAP_PilO PF06864.12 ACL96636.1 - 0.04 12.7 1.1 0.07 11.9 1.1 1.3 1 0 0 1 1 1 0 Pilin accessory protein (PilO) TPR_8 PF13181.6 ACL96636.1 - 0.047 13.9 0.2 19 5.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 ACL96636.1 - 0.14 12.3 7.6 3.8 7.8 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 ACL96636.1 - 0.91 9.5 8.4 41 4.2 0.1 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Na_H_antiport_2 PF13726.6 ACL96636.1 - 1.3 9.2 3.5 2.9 8.1 0.7 2.6 3 0 0 3 3 3 0 Na+-H+ antiporter family adh_short_C2 PF13561.6 ACL96637.1 - 1.3e-63 214.7 0.6 1.6e-63 214.4 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ACL96637.1 - 1.9e-49 167.8 0.4 1.6e-48 164.7 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 ACL96637.1 - 1.5e-12 47.8 0.1 2.2e-12 47.2 0.1 1.1 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 ACL96637.1 - 0.0072 16.9 0.6 0.019 15.5 0.6 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 ACL96637.1 - 0.023 14.2 0.0 0.085 12.3 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 ACL96637.1 - 0.047 13.0 0.0 0.091 12.1 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain HEM4 PF02602.15 ACL96637.1 - 0.056 12.8 0.1 0.093 12.1 0.1 1.2 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD 2-Hacid_dh_C PF02826.19 ACL96637.1 - 0.062 12.7 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DFP PF04127.15 ACL96637.1 - 0.14 12.0 0.8 0.37 10.6 0.8 1.6 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein AHSA1 PF08327.11 ACL96638.1 - 2.5e-31 108.5 0.6 2.9e-31 108.3 0.6 1.0 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein OB_aCoA_assoc PF01796.17 ACL96638.1 - 0.11 12.5 0.1 15 5.7 0.0 2.4 2 0 0 2 2 2 0 DUF35 OB-fold domain, acyl-CoA-associated VasL PF12486.8 ACL96638.1 - 0.17 11.8 0.1 0.23 11.3 0.1 1.2 1 0 0 1 1 1 0 Type VI secretion system, EvfB, or VasL MFS_1 PF07690.16 ACL96639.2 - 1.9e-26 92.9 80.3 1.3e-25 90.1 57.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ACL96639.2 - 8.1e-06 24.9 23.1 8.1e-06 24.9 23.1 3.3 2 2 0 2 2 2 2 Sugar (and other) transporter FG-GAP_2 PF14312.6 ACL96639.2 - 0.053 13.8 0.2 0.17 12.2 0.2 1.9 1 0 0 1 1 1 0 FG-GAP repeat DUF86 PF01934.17 ACL96640.3 - 7.7e-18 64.5 0.0 1e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF86 NTP_transf_2 PF01909.23 ACL96641.1 - 8.1e-13 48.5 0.0 1e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 ACL96641.1 - 2.6e-10 40.2 0.0 3.2e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase MM_CoA_mutase PF01642.22 ACL96642.1 - 5.3e-131 437.7 0.0 6.8e-131 437.3 0.0 1.1 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 ACL96642.1 - 1.5e-15 57.3 0.1 4.1e-15 55.9 0.1 1.8 1 0 0 1 1 1 1 B12 binding domain DUF5486 PF17588.2 ACL96642.1 - 0.15 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5486) MerR PF00376.23 ACL96643.1 - 9.7e-16 57.3 0.5 1.8e-15 56.4 0.5 1.5 1 0 0 1 1 1 1 MerR family regulatory protein MerR_1 PF13411.6 ACL96643.1 - 9.7e-15 54.4 0.0 1.4e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 MerR HTH family regulatory protein MerR-DNA-bind PF09278.11 ACL96643.1 - 4.2e-14 52.8 1.5 4.2e-14 52.8 1.5 1.7 2 0 0 2 2 2 1 MerR, DNA binding DivIC PF04977.15 ACL96643.1 - 0.027 14.2 0.4 0.053 13.3 0.4 1.5 1 0 0 1 1 1 0 Septum formation initiator HTH_31 PF13560.6 ACL96643.1 - 0.033 14.5 0.7 0.31 11.4 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 ACL96643.1 - 0.067 12.7 0.3 0.31 10.6 0.1 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_3 PF01381.22 ACL96643.1 - 0.076 13.1 0.2 0.24 11.5 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix LacI PF00356.21 ACL96643.1 - 0.088 12.6 0.1 0.3 10.9 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family Oxidored_FMN PF00724.20 ACL96644.1 - 7.4e-45 153.7 0.0 9.5e-45 153.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ECH_1 PF00378.20 ACL96645.1 - 2.4e-43 148.3 1.8 2.8e-43 148.1 1.8 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ACL96645.1 - 4.1e-15 56.1 0.4 5.3e-15 55.7 0.4 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ADH_zinc_N PF00107.26 ACL96646.1 - 5.7e-34 116.9 0.2 8.4e-34 116.4 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ACL96646.1 - 5.6e-15 55.2 0.0 4.8e-14 52.2 0.0 2.3 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ACL96646.1 - 7.2e-08 33.6 0.0 1.4e-07 32.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.8 ACL96646.1 - 0.013 15.2 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Beta-lactamase PF00144.24 ACL96648.2 - 1.1e-68 232.0 1.4 1.7e-68 231.3 1.4 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 ACL96648.2 - 1.3e-24 86.6 0.0 2.7e-24 85.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Peptidase_S11 PF00768.20 ACL96648.2 - 0.044 13.2 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Acyl-CoA_dh_1 PF00441.24 ACL96649.2 - 1.4e-41 142.2 7.9 1.4e-41 142.2 7.9 2.3 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ACL96649.2 - 1.8e-30 105.9 0.2 1.8e-30 105.9 0.2 3.0 4 0 0 4 4 4 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ACL96649.2 - 1.4e-17 63.6 0.0 2.7e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ACL96649.2 - 1e-13 51.7 5.2 1e-13 51.7 5.2 2.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain GST_N PF02798.20 ACL96650.1 - 7.8e-15 55.0 0.0 1.2e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ACL96650.1 - 1.8e-13 50.7 0.0 3.3e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ACL96650.1 - 4.4e-09 36.5 0.1 7.6e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ACL96650.1 - 5.9e-09 36.0 0.0 8e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ACL96650.1 - 3.1e-07 30.5 0.0 4.8e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ACL96650.1 - 5.3e-05 23.1 0.5 0.00029 20.8 0.5 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2855 PF11017.8 ACL96651.1 - 1.1e-100 337.7 0.0 1.3e-100 337.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) ADH_N_2 PF16884.5 ACL96651.1 - 0.18 11.7 0.0 1.4 8.9 0.0 2.2 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase EamA PF00892.20 ACL96652.1 - 6.4e-27 94.4 42.9 2.5e-14 53.6 15.7 2.0 2 0 0 2 2 2 2 EamA-like transporter family EHN PF06441.12 ACL96653.1 - 1e-25 90.2 0.0 1.6e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 ACL96653.1 - 6.5e-11 42.4 0.2 1.1e-10 41.6 0.2 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold GFA PF04828.14 ACL96654.1 - 3.5e-21 75.3 0.0 4.6e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme RNA_POL_M_15KD PF02150.16 ACL96654.1 - 0.77 9.7 5.0 17 5.4 2.0 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Beta_elim_lyase PF01212.21 ACL96655.1 - 1.7e-64 218.0 0.9 1.9e-64 217.7 0.9 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase EAL PF00563.20 ACL96656.1 - 3.7e-75 252.5 0.1 5.6e-75 251.9 0.1 1.3 1 0 0 1 1 1 1 EAL domain GGDEF PF00990.21 ACL96656.1 - 6.1e-48 162.6 0.0 1.3e-47 161.5 0.0 1.6 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain PAS_4 PF08448.10 ACL96656.1 - 4.8e-16 59.0 4.5 9.4e-16 58.0 0.1 3.3 3 1 1 4 4 4 1 PAS fold PAS PF00989.25 ACL96656.1 - 8.3e-07 29.0 0.0 7.3e-06 26.0 0.0 2.5 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.7 ACL96656.1 - 2.5e-06 27.7 0.0 1.4e-05 25.3 0.0 2.3 3 0 0 3 3 3 1 PAS domain CBS PF00571.28 ACL96656.1 - 0.053 14.0 0.0 7.3 7.1 0.0 2.9 2 0 0 2 2 2 0 CBS domain CMD PF02627.20 ACL96657.1 - 8.3e-14 51.4 0.1 4.1e-13 49.2 0.0 2.0 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Glyoxalase PF00903.25 ACL96658.1 - 2.6e-18 66.5 0.0 3.3e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ACL96658.1 - 7.1e-07 29.5 0.1 0.0014 18.9 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 ACL96658.1 - 0.01 16.0 0.0 0.02 15.0 0.0 1.5 1 1 0 1 1 1 0 Glyoxalase-like domain Glyoxalase_6 PF18029.1 ACL96658.1 - 0.058 14.2 0.0 0.11 13.3 0.0 1.6 1 1 0 1 1 1 0 Glyoxalase-like domain Phage_holin_4_2 PF04020.13 ACL96659.1 - 1.5e-27 96.3 19.3 1.8e-27 96.0 19.3 1.0 1 0 0 1 1 1 1 Mycobacterial 4 TMS phage holin, superfamily IV Sigma70_r4 PF04545.16 ACL96660.1 - 3.1e-17 61.8 3.6 4e-17 61.5 2.4 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 ACL96660.1 - 7.1e-16 57.7 0.0 1.3e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r1_2 PF00140.20 ACL96660.1 - 5.1e-08 32.8 0.0 1.3e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 Sigma70_r3 PF04539.16 ACL96660.1 - 0.0034 17.4 1.3 1.6 8.8 0.1 2.6 2 0 0 2 2 2 2 Sigma-70 region 3 DUF3431 PF11913.8 ACL96660.1 - 0.0053 16.6 0.2 0.057 13.2 0.0 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3431) HTH_11 PF08279.12 ACL96660.1 - 0.0059 16.5 0.4 0.018 15.0 0.2 1.9 2 0 0 2 2 2 1 HTH domain GntR PF00392.21 ACL96660.1 - 0.044 13.4 0.1 0.14 11.8 0.1 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_23 PF13384.6 ACL96660.1 - 0.049 13.4 0.1 0.77 9.6 0.1 2.6 2 0 0 2 2 2 0 Homeodomain-like domain HTH_15 PF12324.8 ACL96660.1 - 0.092 12.7 0.1 0.86 9.6 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase HTH_3 PF01381.22 ACL96660.1 - 0.095 12.8 0.3 0.34 11.0 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix HTH_10 PF04967.12 ACL96660.1 - 0.43 10.4 2.2 7.7 6.4 0.0 3.6 4 0 0 4 4 4 0 HTH DNA binding domain Abhydrolase_1 PF00561.20 ACL96662.1 - 1e-14 54.8 0.0 9.9e-06 25.4 0.0 3.0 3 0 0 3 3 3 3 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ACL96662.1 - 9.8e-13 47.9 0.0 1.2e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ACL96662.1 - 3.9e-12 47.2 1.5 5.3e-12 46.8 1.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 ACL96662.1 - 6.1e-07 29.5 0.0 1.3e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein FSH1 PF03959.13 ACL96662.1 - 3.7e-05 23.5 0.0 0.0016 18.2 0.1 2.7 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Thioesterase PF00975.20 ACL96662.1 - 0.00035 20.7 0.1 0.00069 19.8 0.1 1.7 1 1 1 2 2 2 1 Thioesterase domain Ser_hydrolase PF06821.13 ACL96662.1 - 0.0022 17.9 0.0 0.0055 16.6 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase DUF2920 PF11144.8 ACL96662.1 - 0.021 14.0 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) UPF0227 PF05728.12 ACL96662.1 - 0.14 12.1 0.0 0.38 10.7 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.7 ACL96662.1 - 0.22 11.3 0.0 2.3 8.0 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family LIDHydrolase PF10230.9 ACL96662.1 - 0.23 11.0 0.0 0.88 9.1 0.0 1.7 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Response_reg PF00072.24 ACL96663.1 - 3.4e-14 52.9 0.0 6.2e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 ACL96665.1 - 4e-30 104.6 0.1 1.1e-29 103.2 0.1 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ACL96665.1 - 5.4e-23 81.3 0.1 1.1e-22 80.3 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ACL96665.1 - 2.3e-20 72.4 0.2 5.9e-20 71.1 0.2 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 ACL96665.1 - 0.0011 18.8 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1541 PF07563.11 ACL96665.1 - 0.1 12.5 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1541) Adenylsucc_synt PF00709.21 ACL96666.1 - 3.5e-165 550.0 0.0 3.9e-165 549.8 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase PagL PF09411.10 ACL96667.1 - 4.6e-14 52.7 0.2 9.5e-14 51.7 0.1 1.5 1 1 0 1 1 1 1 Lipid A 3-O-deacylase (PagL) OMP_b-brl PF13505.6 ACL96667.1 - 0.00031 20.9 6.6 0.0028 17.8 0.4 2.4 1 1 1 2 2 2 2 Outer membrane protein beta-barrel domain OmpA_membrane PF01389.17 ACL96667.1 - 0.026 14.2 0.1 0.3 10.8 0.1 2.2 2 0 0 2 2 2 0 OmpA-like transmembrane domain PALP PF00291.25 ACL96668.1 - 1.5e-77 260.9 2.1 1.7e-77 260.7 2.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ala_racemase_N PF01168.20 ACL96669.1 - 4e-27 95.3 1.2 5.9e-27 94.7 1.2 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.6 ACL96669.1 - 5.3e-25 87.9 0.9 3.5e-24 85.3 0.2 2.4 2 1 0 2 2 2 1 Putative serine dehydratase domain Peptidase_M28 PF04389.17 ACL96670.2 - 2.5e-46 157.9 0.0 4e-46 157.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ACL96670.2 - 2.9e-08 33.6 0.1 7.6e-08 32.3 0.1 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 ACL96670.2 - 7.7e-05 22.5 0.1 0.00048 19.9 0.0 2.1 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 SDH_alpha PF03313.15 ACL96671.1 - 9.1e-97 323.8 12.2 1.1e-96 323.5 12.2 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 ACL96671.1 - 1.7e-54 184.4 0.0 3.4e-54 183.4 0.0 1.5 1 0 0 1 1 1 1 Serine dehydratase beta chain DUF72 PF01904.18 ACL96672.1 - 2.3e-52 178.3 0.0 2.6e-52 178.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF72 DUF1295 PF06966.12 ACL96673.1 - 1.8e-79 266.6 2.1 2.2e-79 266.3 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 ACL96673.1 - 5.5e-06 26.7 1.9 1.1e-05 25.8 0.2 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.16 ACL96673.1 - 3.5e-05 23.8 0.1 8.4e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 ACL96673.1 - 0.00064 20.1 0.2 0.0033 17.8 0.0 2.2 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Thiolase_N PF00108.23 ACL96674.1 - 4e-12 46.0 0.0 2.3e-10 40.3 0.0 2.1 2 0 0 2 2 2 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 ACL96674.1 - 4.8e-08 32.7 0.0 1.3e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ACL96674.1 - 0.00077 19.1 0.9 0.00077 19.1 0.9 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 ACL96674.1 - 0.16 11.8 1.1 0.29 11.0 0.3 1.8 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HxlR PF01638.17 ACL96675.1 - 1e-42 143.9 0.2 2.3e-20 72.3 0.1 2.4 2 0 0 2 2 2 2 HxlR-like helix-turn-helix PadR PF03551.14 ACL96675.1 - 2.5e-06 27.4 0.8 0.014 15.3 0.1 2.3 2 0 0 2 2 2 2 Transcriptional regulator PadR-like family HTH_34 PF13601.6 ACL96675.1 - 0.0002 21.4 0.0 0.16 12.2 0.0 2.2 2 0 0 2 2 2 2 Winged helix DNA-binding domain MarR_2 PF12802.7 ACL96675.1 - 0.059 13.3 0.9 5.9 6.9 0.0 2.9 3 0 0 3 3 3 0 MarR family Mrr_N PF14338.6 ACL96675.1 - 0.076 13.2 0.0 3.8 7.7 0.0 2.6 3 0 0 3 3 3 0 Mrr N-terminal domain MR_MLE_C PF13378.6 ACL96676.1 - 3.6e-20 72.5 0.4 7.2e-20 71.5 0.4 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 ACL96676.1 - 1.5e-09 38.1 1.0 5e-09 36.4 1.0 1.9 1 1 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain PHA_gran_rgn PF09650.10 ACL96678.1 - 2e-16 60.0 0.0 2.4e-16 59.8 0.0 1.0 1 0 0 1 1 1 1 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) gp12-short_mid PF09089.10 ACL96678.1 - 0.035 14.3 0.1 0.042 14.0 0.1 1.2 1 0 0 1 1 1 0 Phage short tail fibre protein gp12, middle domain DUF983 PF06170.12 ACL96679.1 - 1.6e-32 111.8 2.9 1.6e-32 111.8 2.9 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF983) Aminotran_1_2 PF00155.21 ACL96680.1 - 1.6e-14 53.9 0.0 3.3e-14 52.8 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.21 ACL96680.1 - 5.1e-12 45.3 0.6 1.2e-11 44.0 0.6 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Aminotran_MocR PF12897.7 ACL96680.1 - 3.2e-05 22.9 0.0 5.9e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase HTH_Crp_2 PF13545.6 ACL96680.1 - 0.013 15.4 0.2 0.035 14.1 0.2 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain DegT_DnrJ_EryC1 PF01041.17 ACL96680.1 - 0.033 13.5 0.1 0.058 12.7 0.1 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family AMP-binding PF00501.28 ACL96680.1 - 0.037 12.6 0.0 0.062 11.9 0.0 1.5 1 1 0 1 1 1 0 AMP-binding enzyme MarR_2 PF12802.7 ACL96680.1 - 0.082 12.8 2.6 0.38 10.7 0.3 3.0 3 0 0 3 3 3 0 MarR family CoA_binding_2 PF13380.6 ACL96680.1 - 0.14 12.7 0.4 1.3 9.6 0.0 2.5 2 1 0 2 2 2 0 CoA binding domain TetR_N PF00440.23 ACL96682.1 - 2e-17 62.7 0.4 3.6e-17 61.9 0.4 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_33 PF13305.6 ACL96682.1 - 3e-14 53.6 2.0 3.4e-14 53.5 0.7 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_1 PF02909.17 ACL96682.1 - 0.09 12.6 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TetR_C_15 PF17918.1 ACL96682.1 - 0.18 12.5 3.5 1.1 10.1 0.4 2.9 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HlyD_3 PF13437.6 ACL96683.1 - 6.5e-20 71.8 5.4 5.9e-18 65.5 0.9 2.7 3 0 0 3 3 3 2 HlyD family secretion protein HlyD_D23 PF16576.5 ACL96683.1 - 6e-18 64.8 1.9 9e-18 64.3 1.9 1.2 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 ACL96683.1 - 3e-08 33.4 8.8 1.2e-07 31.5 0.1 3.2 3 0 0 3 3 3 2 Biotin-lipoyl like Biotin_lipoyl PF00364.22 ACL96683.1 - 0.00035 20.4 0.1 0.84 9.5 0.0 2.8 2 0 0 2 2 2 2 Biotin-requiring enzyme Peptidase_M23 PF01551.22 ACL96683.1 - 0.033 14.4 0.9 1.5 9.1 0.0 3.3 4 0 0 4 4 4 0 Peptidase family M23 Endonuc-BsobI PF09194.10 ACL96683.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease BsobI HlyD PF00529.20 ACL96683.1 - 0.16 11.8 3.4 0.18 11.7 2.1 1.9 1 1 0 1 1 1 0 HlyD membrane-fusion protein of T1SS DUF4232 PF14016.6 ACL96683.1 - 8.6 6.5 10.5 0.37 10.9 2.0 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF4232) ACR_tran PF00873.19 ACL96684.1 - 6.3e-200 666.4 0.0 7.2e-200 666.2 0.0 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family SecD_SecF PF02355.16 ACL96684.1 - 8e-11 41.7 16.2 9.7e-06 25.1 5.4 2.3 2 0 0 2 2 2 2 Protein export membrane protein MMPL PF03176.15 ACL96684.1 - 1.2e-06 27.7 32.2 0.00014 20.9 11.2 2.5 2 1 0 2 2 2 2 MMPL family bMG1 PF17970.1 ACL96684.1 - 0.0075 16.3 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 Bacterial Alpha-2-macroglobulin MG1 domain VWA_2 PF13519.6 ACL96684.1 - 0.11 13.1 0.0 2.5 8.8 0.0 3.1 3 0 0 3 3 3 0 von Willebrand factor type A domain Spore_YhcN_YlaJ PF09580.10 ACL96684.1 - 6.8 6.8 7.9 1.9 8.6 0.5 2.9 3 0 0 3 3 3 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Amino_oxidase PF01593.24 ACL96686.1 - 1.3e-13 51.0 3.1 7.1e-13 48.6 0.3 2.7 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 ACL96686.1 - 4.2e-11 43.0 7.0 1.1e-09 38.4 7.0 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ACL96686.1 - 2.1e-10 40.7 0.2 5.9e-10 39.2 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ACL96686.1 - 1.9e-07 30.6 0.1 4.2e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ACL96686.1 - 3.2e-07 30.8 0.2 0.00097 19.7 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ACL96686.1 - 3.4e-06 26.7 1.0 0.00016 21.2 0.7 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 ACL96686.1 - 6.5e-06 25.6 2.8 2e-05 24.0 0.9 2.1 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 ACL96686.1 - 1.9e-05 23.6 0.8 0.0028 16.4 1.1 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 ACL96686.1 - 0.00027 20.1 13.0 0.00035 19.8 4.7 2.8 3 0 0 3 3 3 2 FAD binding domain GIDA PF01134.22 ACL96686.1 - 0.0031 16.7 0.8 0.0031 16.7 0.8 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 ACL96686.1 - 0.033 13.4 0.4 0.056 12.7 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 ACL96686.1 - 0.053 12.4 0.6 0.43 9.4 0.3 2.1 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.6 ACL96686.1 - 0.097 12.7 0.1 0.24 11.4 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding XdhC_C PF13478.6 ACL96686.1 - 0.22 12.1 0.8 0.9 10.1 0.0 2.1 2 0 0 2 2 2 0 XdhC Rossmann domain Pyr_redox_3 PF13738.6 ACL96686.1 - 0.55 9.4 2.7 0.85 8.8 2.7 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ACL96686.1 - 0.67 8.9 3.8 2.4 7.1 1.8 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 ACL96686.1 - 2.4 7.5 3.8 3.3 7.0 0.3 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ring_hydroxyl_A PF00848.19 ACL96687.1 - 9.5e-31 107.4 0.0 1.4e-30 106.9 0.0 1.2 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 ACL96687.1 - 7.2e-22 77.1 0.0 1.3e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 ACL96687.1 - 0.0061 16.5 0.0 0.0096 15.8 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain TetR_C_6 PF13977.6 ACL96688.1 - 4.7e-23 81.6 8.1 4.7e-23 81.6 8.1 2.6 2 1 1 3 3 3 1 BetI-type transcriptional repressor, C-terminal TetR_N PF00440.23 ACL96688.1 - 1.9e-11 43.6 2.2 1.4e-10 40.8 0.2 2.5 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family TetR_C_31 PF17940.1 ACL96688.1 - 3.5e-06 27.2 5.1 3.5e-06 27.2 5.1 3.2 1 1 0 3 3 3 1 Tetracyclin repressor-like, C-terminal domain TetR_C_28 PF17937.1 ACL96688.1 - 0.00058 20.3 5.7 0.00058 20.3 5.7 2.7 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_15 PF17918.1 ACL96688.1 - 0.0055 17.4 10.8 0.63 10.8 1.1 3.1 3 0 0 3 3 3 2 Tetracyclin repressor-like, C-terminal domain HTH_23 PF13384.6 ACL96688.1 - 0.072 12.9 1.1 0.61 10.0 0.0 2.6 2 0 0 2 2 2 0 Homeodomain-like domain DUF2188 PF09954.9 ACL96689.2 - 0.019 15.1 1.2 0.027 14.6 0.4 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) PAC4 PF16093.5 ACL96689.2 - 0.12 12.5 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 Amidohydro_1 PF01979.20 ACL96690.1 - 1.7e-57 195.3 2.4 2e-57 195.1 2.4 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ACL96690.1 - 2.8e-12 46.8 8.0 5.5e-07 29.4 4.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family TraC PF07820.12 ACL96690.1 - 5.4 7.4 7.1 1 9.8 1.8 2.3 2 1 0 2 2 2 0 TraC-like protein AA_permease_2 PF13520.6 ACL96691.1 - 1.1e-53 182.7 47.6 1.3e-53 182.4 47.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ACL96691.1 - 2e-33 115.8 40.5 2.7e-33 115.3 40.5 1.1 1 0 0 1 1 1 1 Amino acid permease TonB_dep_Rec PF00593.24 ACL96692.1 - 3e-38 132.9 28.1 5e-37 128.9 28.1 2.0 1 1 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 ACL96692.1 - 1.1e-14 54.9 1.3 3.1e-14 53.4 1.3 1.8 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain DUF4902 PF16245.5 ACL96692.1 - 0.072 13.0 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4902) Sulfotransfer_3 PF13469.6 ACL96693.1 - 8.7e-41 140.7 0.2 4.8e-40 138.3 0.0 2.4 3 0 0 3 3 2 1 Sulfotransferase family TPR_14 PF13428.6 ACL96693.1 - 7.5e-16 57.5 62.1 0.00043 20.9 2.3 9.9 4 2 6 10 10 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 ACL96693.1 - 3.2e-15 54.9 35.4 0.0061 16.6 0.1 9.1 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 ACL96693.1 - 1.6e-13 51.1 63.3 3.2e-07 30.9 2.0 7.6 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 ACL96693.1 - 1.3e-11 43.8 5.3 0.013 15.6 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat Sulfotransfer_1 PF00685.27 ACL96693.1 - 3.9e-11 42.9 0.0 7.3e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase domain TPR_17 PF13431.6 ACL96693.1 - 5.3e-11 42.1 13.0 0.0026 18.0 0.8 8.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 ACL96693.1 - 9.5e-11 42.1 44.8 8.7e-05 23.0 6.7 7.1 4 2 1 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 ACL96693.1 - 1.4e-09 37.5 6.2 0.0053 16.4 0.1 5.6 4 1 1 5 5 5 2 TPR repeat ANAPC3 PF12895.7 ACL96693.1 - 5e-09 36.3 8.8 6e-07 29.6 3.7 3.3 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 ACL96693.1 - 7e-08 32.0 17.3 0.65 9.9 0.0 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 ACL96693.1 - 7.6e-07 28.7 23.3 0.038 14.0 0.0 7.1 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 ACL96693.1 - 0.00043 20.4 37.2 0.15 12.3 0.3 5.9 2 2 2 5 5 5 4 Tetratricopeptide repeat TPR_6 PF13174.6 ACL96693.1 - 0.00062 20.2 4.6 0.022 15.4 0.3 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 ACL96693.1 - 0.0018 18.5 50.6 0.0083 16.4 5.9 8.0 4 1 5 9 9 9 5 Tetratricopeptide repeat DUF4376 PF14301.6 ACL96693.1 - 0.0063 16.9 0.1 0.033 14.6 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4376) BTAD PF03704.17 ACL96693.1 - 0.054 13.9 0.1 0.054 13.9 0.1 4.1 3 1 2 5 5 5 0 Bacterial transcriptional activator domain HrpB1_HrpK PF09613.10 ACL96693.1 - 0.12 12.1 11.9 0.025 14.2 2.4 3.3 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) Wzy_C_2 PF11846.8 ACL96693.1 - 0.14 12.1 13.4 0.19 11.6 0.9 4.7 2 2 3 5 5 5 0 Virulence factor membrane-bound polymerase, C-terminal Fis1_TPR_C PF14853.6 ACL96693.1 - 0.95 9.6 6.0 2.9 8.0 0.2 3.7 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat DAO PF01266.24 ACL96694.1 - 1.2e-49 169.8 10.5 1.3e-49 169.7 10.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ACL96694.1 - 0.05 12.8 0.2 0.47 9.6 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ACL96694.1 - 0.075 13.0 1.0 2.9 7.9 0.2 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 ACL96694.1 - 0.2 10.3 3.0 1.4 7.5 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_8 PF13450.6 ACL96694.1 - 0.42 10.9 3.5 1 9.7 2.1 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Gln-synt_C PF00120.24 ACL96695.1 - 1.2e-109 366.5 0.0 1.4e-109 366.3 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 ACL96695.1 - 0.0034 17.1 0.0 0.0066 16.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Gln-synt_N_2 PF16952.5 ACL96695.1 - 0.03 14.1 0.0 0.21 11.4 0.0 2.1 1 1 0 1 1 1 0 Glutamine synthetase N-terminal domain Phage_TAC_13 PF16459.5 ACL96695.1 - 0.085 13.3 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone, TAC ParE_toxin PF05016.15 ACL96697.1 - 1.1e-15 57.9 0.2 1.3e-15 57.8 0.2 1.0 1 0 0 1 1 1 1 ParE toxin of type II toxin-antitoxin system, parDE HTH_12 PF08461.10 ACL96697.1 - 0.041 13.8 0.0 0.066 13.2 0.0 1.5 1 1 0 1 1 1 0 Ribonuclease R winged-helix domain Prot_ATP_OB_N PF17758.1 ACL96697.1 - 0.08 12.6 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain Aminotran_3 PF00202.21 ACL96698.1 - 1.9e-90 303.4 0.0 2.4e-90 303.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Peptidase_C26 PF07722.13 ACL96699.1 - 1.8e-55 188.1 0.0 2e-55 187.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase C26 GATase PF00117.28 ACL96699.1 - 2.3e-13 50.3 0.0 3.7e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I ABC_tran PF00005.27 ACL96700.1 - 3.6e-38 131.2 0.0 5.9e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter TOBE_2 PF08402.10 ACL96700.1 - 2.2e-19 69.4 0.0 4.5e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 TOBE domain AAA_21 PF13304.6 ACL96700.1 - 2.8e-09 37.2 0.0 0.00011 22.1 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ACL96700.1 - 0.00016 22.1 0.1 0.00035 21.0 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 ACL96700.1 - 0.00018 21.0 0.0 0.014 14.8 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ACL96700.1 - 0.00038 20.8 0.2 0.0028 17.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 ACL96700.1 - 0.00062 20.2 0.0 0.11 12.9 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 ACL96700.1 - 0.0048 17.1 0.2 0.033 14.4 0.1 2.1 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ACL96700.1 - 0.0089 15.9 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 ACL96700.1 - 0.013 15.1 0.0 0.048 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 ACL96700.1 - 0.017 15.1 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 ACL96700.1 - 0.028 14.2 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 ACL96700.1 - 0.036 14.6 0.0 0.067 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 ACL96700.1 - 0.066 12.6 0.0 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 ACL96700.1 - 0.075 13.0 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 ACL96700.1 - 0.11 12.6 0.2 0.35 11.0 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 ACL96700.1 - 0.13 12.2 0.1 0.47 10.4 0.1 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) BPD_transp_1 PF00528.22 ACL96701.1 - 5.5e-17 62.1 24.0 7.4e-16 58.4 24.0 2.2 1 1 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component NicO PF03824.16 ACL96701.1 - 0.029 13.7 0.5 0.029 13.7 0.5 2.2 2 0 0 2 2 2 0 High-affinity nickel-transport protein COX7C PF02935.16 ACL96701.1 - 0.35 11.1 3.3 1.4 9.2 3.3 2.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc BPD_transp_1 PF00528.22 ACL96703.2 - 8.5e-19 68.0 11.9 8.5e-19 68.0 11.9 2.1 1 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component Ycf9 PF01737.17 ACL96703.2 - 0.13 12.1 5.5 0.33 10.9 2.2 2.6 2 0 0 2 2 2 0 YCF9 DUF393 PF04134.12 ACL96703.2 - 0.58 11.5 2.8 1.9 9.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF393 SBP_bac_8 PF13416.6 ACL96704.1 - 1.1e-37 130.4 0.0 1.5e-37 130.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.6 ACL96704.1 - 1.2e-29 103.4 0.5 2.1e-29 102.7 0.3 1.5 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 ACL96704.1 - 7.2e-18 65.6 0.1 5.6e-17 62.7 0.1 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 ACL96704.1 - 9e-10 38.7 0.0 2.1e-09 37.5 0.0 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein TAT_signal PF10518.9 ACL96704.1 - 0.016 15.1 2.3 0.026 14.3 2.3 1.4 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Lipoprotein_8 PF02030.15 ACL96704.1 - 0.05 12.3 0.0 0.089 11.5 0.0 1.3 1 0 0 1 1 1 0 Hypothetical lipoprotein (MG045 family) Gln-synt_C PF00120.24 ACL96705.1 - 5.4e-105 351.2 0.0 6.3e-105 351.0 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 ACL96705.1 - 0.015 15.0 0.0 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 Glutamine synthetase, beta-Grasp domain Gln-synt_N_2 PF16952.5 ACL96705.1 - 0.046 13.5 0.1 0.23 11.3 0.1 2.0 1 1 0 1 1 1 0 Glutamine synthetase N-terminal domain Aminotran_3 PF00202.21 ACL96706.1 - 6.8e-44 150.1 0.0 8.7e-44 149.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 ACL96706.1 - 0.0045 16.2 0.0 0.013 14.7 0.0 1.9 2 1 0 2 2 2 1 Aminotransferase class I and II Aldedh PF00171.22 ACL96707.1 - 2.1e-172 573.8 0.7 2.4e-172 573.6 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.22 ACL96708.1 - 4.7e-170 566.1 0.0 5.3e-170 565.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FCD PF07729.12 ACL96709.1 - 4e-21 75.7 13.1 1.8e-20 73.6 9.9 2.4 2 0 0 2 2 2 1 FCD domain GntR PF00392.21 ACL96709.1 - 3.4e-15 55.5 0.1 7.2e-15 54.4 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_24 PF13412.6 ACL96709.1 - 0.001 18.6 0.0 0.0021 17.6 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_10 PF04967.12 ACL96709.1 - 0.0042 16.9 0.2 0.029 14.2 0.0 2.2 2 0 0 2 2 2 1 HTH DNA binding domain RPA_C PF08784.11 ACL96709.1 - 0.0075 16.9 0.0 0.013 16.1 0.0 1.3 1 0 0 1 1 1 1 Replication protein A C terminal HTH_28 PF13518.6 ACL96709.1 - 0.061 13.5 1.5 0.64 10.2 0.0 2.7 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_29 PF13551.6 ACL96709.1 - 0.064 13.3 0.0 0.064 13.3 0.0 2.5 3 0 0 3 3 3 0 Winged helix-turn helix Aminotran_3 PF00202.21 ACL96710.2 - 2e-96 323.1 0.0 2.4e-96 322.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 ACL96710.2 - 0.0026 17.0 0.0 0.0038 16.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ACL96710.2 - 0.063 12.5 0.0 0.087 12.1 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase DUF2332 PF10094.9 ACL96711.2 - 1.9e-92 310.3 12.5 2.1e-92 310.2 12.5 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2332) MCPsignal PF00015.21 ACL96712.1 - 3.5e-44 150.6 16.7 3.5e-44 150.6 16.7 4.0 3 2 1 4 4 4 2 Methyl-accepting chemotaxis protein (MCP) signalling domain CHASE3 PF05227.13 ACL96712.1 - 1.7e-21 76.6 2.3 1.7e-21 76.6 2.3 4.6 4 1 0 4 4 4 2 CHASE3 domain HAMP PF00672.25 ACL96712.1 - 2.1e-11 44.0 12.8 2.1e-09 37.6 1.6 5.2 4 1 0 4 4 4 2 HAMP domain IreB PF06135.12 ACL96712.1 - 0.0075 16.5 0.1 0.024 14.8 0.1 1.9 1 0 0 1 1 1 1 IreB regulatory phosphoprotein 4HB_MCP_1 PF12729.7 ACL96712.1 - 0.016 14.7 0.1 0.016 14.7 0.1 3.6 4 1 1 5 5 5 0 Four helix bundle sensory module for signal transduction Focal_AT PF03623.13 ACL96712.1 - 0.14 12.2 2.6 0.41 10.6 1.7 2.4 2 0 0 2 2 2 0 Focal adhesion targeting region DUF4386 PF14329.6 ACL96712.1 - 0.28 11.0 5.9 4 7.3 1.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4386) Sec8_exocyst PF04048.14 ACL96712.1 - 2.6 7.9 5.7 3.2 7.7 0.3 3.1 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain zf-C4H2 PF10146.9 ACL96712.1 - 3 8.1 6.0 4.4 7.6 0.0 3.4 3 1 0 4 4 4 0 Zinc finger-containing protein TonB_dep_Rec PF00593.24 ACL96713.1 - 1.9e-25 90.7 26.9 1.9e-25 90.7 26.9 2.2 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 ACL96713.1 - 4.4e-17 62.6 0.6 2.1e-16 60.4 0.6 2.3 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain EF-hand_5 PF13202.6 ACL96713.1 - 0.12 11.9 0.5 2.1 8.0 0.0 2.6 2 0 0 2 2 2 0 EF hand TonB_dep_Rec PF00593.24 ACL96714.1 - 5.8e-30 105.6 24.3 5.8e-30 105.6 24.3 2.3 1 1 1 2 2 2 1 TonB dependent receptor Plug PF07715.15 ACL96714.1 - 1.7e-15 57.5 2.5 1.7e-15 57.5 0.6 2.2 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain EF-hand_5 PF13202.6 ACL96714.1 - 0.04 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 EF hand EAL PF00563.20 ACL96715.2 - 1e-46 159.4 0.0 1.4e-46 159.0 0.0 1.1 1 0 0 1 1 1 1 EAL domain Penicillinase_R PF03965.16 ACL96717.2 - 4.3e-13 49.6 0.0 5.6e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Penicillinase repressor PaaX PF07848.12 ACL96717.2 - 0.0011 19.1 0.1 0.0018 18.5 0.1 1.3 1 0 0 1 1 1 1 PaaX-like protein MarR_2 PF12802.7 ACL96717.2 - 0.0029 17.4 0.1 0.0075 16.1 0.1 1.7 1 0 0 1 1 1 1 MarR family AbiEi_4 PF13338.6 ACL96717.2 - 0.012 15.8 0.2 0.021 14.9 0.2 1.4 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin TrmB PF01978.19 ACL96717.2 - 0.019 14.8 0.0 0.29 11.1 0.0 2.2 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB GntR PF00392.21 ACL96717.2 - 0.067 12.9 0.5 0.2 11.3 0.3 1.9 1 1 0 1 1 1 0 Bacterial regulatory proteins, gntR family EAP30 PF04157.16 ACL96717.2 - 0.096 12.0 0.6 0.14 11.4 0.0 1.5 2 0 0 2 2 2 0 EAP30/Vps36 family Peptidase_M56 PF05569.11 ACL96718.1 - 9.6e-27 93.9 0.0 1.2e-26 93.6 0.0 1.1 1 0 0 1 1 1 1 BlaR1 peptidase M56 Peptidase_M48 PF01435.18 ACL96718.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M48 PemK_toxin PF02452.17 ACL96720.1 - 3e-11 43.7 0.0 3.6e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 PemK-like, MazF-like toxin of type II toxin-antitoxin system UPF0669 PF17065.5 ACL96720.1 - 0.079 12.7 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Putative cytokine, C6ORF120 Chorismate_synt PF01264.21 ACL96721.1 - 2.8e-132 440.4 0.0 3.1e-132 440.2 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Response_reg PF00072.24 ACL96722.1 - 2.7e-25 88.7 0.0 3.2e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain BRCT_3 PF18428.1 ACL96722.1 - 0.084 13.0 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain DUF2726 PF10881.8 ACL96722.1 - 0.094 12.6 0.0 0.83 9.6 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2726) DUF726 PF05277.12 ACL96723.1 - 0.075 12.0 5.9 0.078 11.9 5.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Gly-zipper_Omp PF13488.6 ACL96723.1 - 3.1 7.9 22.5 0.073 13.1 7.1 2.2 1 1 1 2 2 2 0 Glycine zipper Cupin_2 PF07883.11 ACL96724.3 - 2.4e-12 46.4 0.1 3.4e-12 45.9 0.1 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 ACL96724.3 - 8.4e-05 22.2 0.0 0.00011 21.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.12 ACL96724.3 - 8.9e-05 22.3 0.0 0.00012 21.9 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ AraC_binding PF02311.19 ACL96724.3 - 0.00013 21.8 0.1 0.0002 21.3 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_6 PF12852.7 ACL96724.3 - 0.016 14.9 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Cupin 3-HAO PF06052.12 ACL96724.3 - 0.026 14.2 0.0 0.029 14.0 0.0 1.1 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase CENP-C_C PF11699.8 ACL96724.3 - 0.044 14.0 0.0 0.058 13.6 0.0 1.2 1 0 0 1 1 1 0 Mif2/CENP-C like PTPS PF01242.19 ACL96725.1 - 1.7e-24 86.2 0.0 1.9e-24 86.0 0.0 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase Radical_SAM PF04055.21 ACL96726.1 - 1e-06 29.2 0.0 1.3e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 ACL96726.1 - 4.5e-05 23.6 0.0 0.00012 22.2 0.0 1.7 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 ACL96726.1 - 0.019 15.2 0.1 0.036 14.3 0.1 1.5 1 1 0 1 1 1 0 4Fe-4S single cluster domain QueC PF06508.13 ACL96727.1 - 7e-76 254.4 0.0 8.1e-76 254.2 0.0 1.0 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.19 ACL96727.1 - 0.0057 16.0 0.0 0.0071 15.7 0.0 1.1 1 0 0 1 1 1 1 Arginosuccinate synthase ThiI PF02568.14 ACL96727.1 - 0.013 15.0 0.0 0.047 13.3 0.0 2.0 1 1 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.19 ACL96727.1 - 0.085 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family TonB_dep_Rec PF00593.24 ACL96728.1 - 5.7e-30 105.6 61.7 1.1e-28 101.4 55.6 3.1 2 1 0 2 2 2 1 TonB dependent receptor Plug PF07715.15 ACL96728.1 - 7.1e-17 61.9 1.9 1.9e-16 60.6 1.1 2.3 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain Response_reg PF00072.24 ACL96730.2 - 7.6e-26 90.5 0.9 3.4e-25 88.4 0.2 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 ACL96730.2 - 2.9e-10 40.6 0.0 4.7e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4012 PF13196.6 ACL96730.2 - 0.096 13.1 0.2 1.1 9.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4012) DUF962 PF06127.11 ACL96731.3 - 2.5e-35 120.4 1.1 2.8e-35 120.3 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF962) HTH_3 PF01381.22 ACL96732.2 - 8.1e-14 51.4 0.1 1.2e-13 50.8 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 ACL96732.2 - 7.5e-10 39.0 1.4 1.6e-09 38.0 0.1 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 ACL96732.2 - 6.3e-08 32.5 0.0 1e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 ACL96732.2 - 0.0012 19.2 0.0 0.0021 18.5 0.0 1.4 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain YdaS_antitoxin PF15943.5 ACL96732.2 - 0.0089 15.9 0.1 0.02 14.7 0.0 1.7 2 0 0 2 2 2 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT BetR PF08667.10 ACL96732.2 - 0.024 14.7 0.0 0.033 14.2 0.0 1.2 1 0 0 1 1 1 0 BetR domain HTH_Crp_2 PF13545.6 ACL96732.2 - 0.068 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_23 PF13384.6 ACL96732.2 - 0.12 12.2 0.5 1.2 9.1 0.0 2.5 2 1 1 3 3 3 0 Homeodomain-like domain PilZ PF07238.14 ACL96733.2 - 2.7e-07 30.9 0.1 4e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 PilZ domain Glucokinase PF02685.16 ACL96734.1 - 1.3e-60 205.0 0.0 1.6e-60 204.8 0.0 1.0 1 0 0 1 1 1 1 Glucokinase Cys_Met_Meta_PP PF01053.20 ACL96735.1 - 4.3e-141 469.9 0.0 4.9e-141 469.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 ACL96735.1 - 2.9e-10 39.9 0.0 4e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 ACL96735.1 - 1.9e-09 37.0 0.0 5.3e-08 32.2 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 ACL96735.1 - 3.5e-09 36.4 0.7 1.8e-08 34.1 0.4 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 ACL96735.1 - 6.7e-07 28.2 0.0 1.1e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.21 ACL96735.1 - 0.00077 18.8 0.2 0.0011 18.3 0.2 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.16 ACL96735.1 - 0.0077 15.1 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein AAA_33 PF13671.6 ACL96735.1 - 0.045 13.9 0.6 4.7 7.4 0.2 2.4 1 1 1 2 2 2 0 AAA domain NAD_binding_10 PF13460.6 ACL96735.1 - 0.062 13.2 0.4 0.35 10.7 0.1 2.2 2 0 0 2 2 2 0 NAD(P)H-binding PE PF00934.20 ACL96735.1 - 0.45 10.9 0.1 0.45 10.9 0.1 2.8 4 0 0 4 4 4 0 PE family HTH_24 PF13412.6 ACL96736.2 - 8.7e-22 76.4 0.3 1.3e-21 75.9 0.3 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding AsnC_trans_reg PF01037.21 ACL96736.2 - 6e-20 71.0 0.0 9.6e-20 70.3 0.0 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_AsnC-type PF13404.6 ACL96736.2 - 1.1e-18 66.7 0.8 2.1e-18 65.9 0.8 1.5 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain MarR_2 PF12802.7 ACL96736.2 - 0.00012 21.9 0.1 0.00018 21.3 0.1 1.3 1 0 0 1 1 1 1 MarR family HTH_Crp_2 PF13545.6 ACL96736.2 - 0.00044 20.2 0.0 0.00091 19.2 0.0 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_11 PF08279.12 ACL96736.2 - 0.00047 20.0 0.0 0.00084 19.2 0.0 1.4 1 0 0 1 1 1 1 HTH domain MarR PF01047.22 ACL96736.2 - 0.00054 19.8 0.0 0.00087 19.2 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 ACL96736.2 - 0.0012 18.9 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 ACL96736.2 - 0.0035 17.4 0.1 0.0063 16.6 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 ACL96736.2 - 0.0042 16.8 0.2 0.055 13.3 0.0 2.2 2 0 0 2 2 2 1 IclR helix-turn-helix domain Rrf2 PF02082.20 ACL96736.2 - 0.042 14.2 0.0 0.069 13.5 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator HTH_DeoR PF08220.12 ACL96736.2 - 0.046 13.5 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_5 PF01022.20 ACL96736.2 - 0.055 13.4 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_CodY PF08222.11 ACL96736.2 - 0.081 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 CodY helix-turn-helix domain HWE_HK PF07536.14 ACL96737.1 - 6.2e-29 100.5 0.1 2.6e-28 98.5 0.0 2.1 2 0 0 2 2 2 1 HWE histidine kinase PAS_4 PF08448.10 ACL96737.1 - 2.4e-17 63.2 2.3 4.2e-11 43.1 0.1 2.8 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.7 ACL96737.1 - 9.5e-09 35.1 0.1 2.4e-06 27.4 0.1 3.0 3 0 0 3 3 3 1 PAS domain PAS PF00989.25 ACL96737.1 - 2.3e-08 34.0 0.0 1e-07 31.9 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 ACL96737.1 - 9.1e-08 32.3 0.0 2.4e-06 27.7 0.0 2.3 2 0 0 2 2 2 1 PAS domain HisKA_2 PF07568.12 ACL96737.1 - 2.4e-06 27.5 0.0 6.5e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase PAS_3 PF08447.12 ACL96737.1 - 0.0041 17.4 0.0 0.22 11.8 0.0 2.5 2 0 0 2 2 2 1 PAS fold HATPase_c_2 PF13581.6 ACL96737.1 - 0.017 15.1 0.0 0.04 13.9 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain PAS_7 PF12860.7 ACL96737.1 - 0.043 14.0 0.0 3 8.0 0.0 2.8 2 1 0 2 2 2 0 PAS fold DUF4996 PF16387.5 ACL96740.1 - 1.5e-24 86.4 0.0 2e-23 82.8 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function GDPD PF03009.17 ACL96740.1 - 1.7e-22 80.4 0.0 2.7e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 ACL96740.1 - 0.15 12.6 0.3 0.67 10.5 0.0 2.3 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family Glycos_transf_1 PF00534.20 ACL96741.1 - 1.3e-37 129.0 0.0 2e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ACL96741.1 - 7.7e-33 113.8 0.0 1.4e-32 112.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 ACL96741.1 - 2e-13 50.5 0.0 3.8e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 TetR_C_6 PF13977.6 ACL96741.1 - 0.22 11.7 4.7 2.9 8.2 3.2 2.8 2 1 1 3 3 3 0 BetI-type transcriptional repressor, C-terminal DAO PF01266.24 ACL96742.1 - 2.4e-61 208.3 3.2 2.7e-61 208.1 3.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ACL96742.1 - 1.3e-07 31.8 1.8 3.4e-07 30.4 1.8 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ACL96742.1 - 1e-06 28.2 0.1 1.6e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 ACL96742.1 - 1.6e-05 24.2 1.4 2.9e-05 23.4 1.4 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ACL96742.1 - 8.3e-05 21.5 0.5 0.0003 19.6 0.8 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 ACL96742.1 - 0.00059 19.3 0.6 0.00067 19.1 0.6 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ACL96742.1 - 0.00086 18.6 1.3 0.0012 18.2 1.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ACL96742.1 - 0.0041 16.4 0.9 0.0076 15.5 0.9 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ACL96742.1 - 0.0063 17.1 1.7 0.012 16.1 1.7 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ACL96742.1 - 0.02 14.0 0.5 0.026 13.6 0.5 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 ACL96742.1 - 0.02 14.1 1.7 0.02 14.1 1.7 1.6 2 0 0 2 2 2 0 FAD binding domain ApbA PF02558.16 ACL96742.1 - 0.079 12.6 1.3 0.13 11.9 1.3 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Amino_oxidase PF01593.24 ACL96742.1 - 0.097 11.9 0.4 0.17 11.1 0.4 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase adh_short PF00106.25 ACL96743.1 - 8.6e-53 178.7 0.0 1.2e-52 178.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ACL96743.1 - 1e-41 143.0 0.1 1.3e-41 142.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ACL96743.1 - 1.7e-11 44.3 0.0 2.4e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ACL96743.1 - 0.0023 17.4 0.1 0.012 15.1 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family POR PF01558.18 ACL96744.1 - 7.6e-21 75.0 1.1 2.5e-20 73.3 0.7 2.1 3 0 0 3 3 3 1 Pyruvate ferredoxin/flavodoxin oxidoreductase TPP_enzyme_C PF02775.21 ACL96744.1 - 1.6e-05 24.8 0.9 4.2e-05 23.4 0.9 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_10 PF13237.6 ACL96744.1 - 1.8 8.8 7.1 5.8 7.1 0.2 2.7 2 1 1 3 3 3 0 4Fe-4S dicluster domain HTH_24 PF13412.6 ACL96745.2 - 2.9e-19 68.4 0.0 4.7e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding AsnC_trans_reg PF01037.21 ACL96745.2 - 2.3e-18 65.9 0.0 3.6e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_AsnC-type PF13404.6 ACL96745.2 - 1.8e-17 62.9 0.3 3.1e-17 62.1 0.3 1.4 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain MarR_2 PF12802.7 ACL96745.2 - 1.8e-07 30.9 0.4 3.1e-07 30.2 0.2 1.5 2 0 0 2 2 1 1 MarR family HTH_Crp_2 PF13545.6 ACL96745.2 - 2.1e-07 30.8 0.4 5.9e-07 29.4 0.1 1.8 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain HTH_20 PF12840.7 ACL96745.2 - 9.6e-07 28.8 0.1 1.8e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.22 ACL96745.2 - 2e-06 27.6 0.0 5.5e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 MarR family HTH_11 PF08279.12 ACL96745.2 - 1.8e-05 24.6 0.1 3.2e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 HTH domain HTH_IclR PF09339.10 ACL96745.2 - 0.0004 20.1 0.0 0.00083 19.1 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain LexA_DNA_bind PF01726.16 ACL96745.2 - 0.0006 19.5 0.0 0.0013 18.5 0.0 1.6 1 1 0 1 1 1 1 LexA DNA binding domain TrmB PF01978.19 ACL96745.2 - 0.0012 18.7 0.0 0.0054 16.6 0.0 1.9 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_Tnp_ISL3 PF13542.6 ACL96745.2 - 0.0021 17.4 0.1 0.0079 15.6 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_1 PF00126.27 ACL96745.2 - 0.0021 18.0 0.6 0.014 15.3 0.0 2.4 3 0 0 3 3 3 1 Bacterial regulatory helix-turn-helix protein, lysR family Sigma70_r4_2 PF08281.12 ACL96745.2 - 0.0073 16.0 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 ACL96745.2 - 0.0083 15.6 0.0 0.036 13.6 0.0 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_CodY PF08222.11 ACL96745.2 - 0.011 15.3 0.2 0.026 14.1 0.2 1.5 1 0 0 1 1 1 0 CodY helix-turn-helix domain HTH_23 PF13384.6 ACL96745.2 - 0.013 15.3 0.1 0.022 14.6 0.1 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_DeoR PF08220.12 ACL96745.2 - 0.025 14.3 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_28 PF13518.6 ACL96745.2 - 0.026 14.6 0.1 0.044 13.9 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_27 PF13463.6 ACL96745.2 - 0.027 15.0 0.1 0.052 14.0 0.0 1.5 2 0 0 2 2 1 0 Winged helix DNA-binding domain GntR PF00392.21 ACL96745.2 - 0.027 14.1 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_38 PF13936.6 ACL96745.2 - 0.028 14.2 0.1 0.068 12.9 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_29 PF13551.6 ACL96745.2 - 0.033 14.2 0.1 0.054 13.5 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn helix HTH_5 PF01022.20 ACL96745.2 - 0.043 13.7 0.1 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HemN_C PF06969.16 ACL96745.2 - 0.048 13.7 0.0 0.19 11.8 0.0 2.0 3 0 0 3 3 2 0 HemN C-terminal domain DprA_WH PF17782.1 ACL96745.2 - 0.052 13.7 0.2 0.096 12.8 0.2 1.4 1 0 0 1 1 1 0 DprA winged helix domain Rrf2 PF02082.20 ACL96745.2 - 0.063 13.6 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator HTH_47 PF16221.5 ACL96745.2 - 0.097 12.2 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 winged helix-turn-helix RPA_C PF08784.11 ACL96745.2 - 0.1 13.2 0.0 0.16 12.6 0.0 1.3 1 0 0 1 1 1 0 Replication protein A C terminal Pirin PF02678.16 ACL96746.1 - 2.2e-33 114.5 0.2 3.4e-33 113.8 0.2 1.3 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 ACL96746.1 - 1.8e-27 95.7 0.0 3e-26 91.8 0.0 2.2 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Amidohydro_2 PF04909.14 ACL96747.2 - 3.7e-45 154.9 0.8 4.3e-45 154.7 0.8 1.0 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.22 ACL96748.1 - 1.2e-74 251.6 0.0 1.5e-74 251.3 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Abi_HHR PF07815.14 ACL96748.1 - 0.21 11.8 0.0 0.4 10.9 0.0 1.4 1 0 0 1 1 1 0 Abl-interactor HHR CorA PF01544.18 ACL96749.1 - 5.9e-62 209.6 0.0 6.6e-62 209.5 0.0 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Wzz PF02706.15 ACL96750.1 - 0.054 13.8 1.3 0.092 13.1 0.1 2.0 1 1 2 3 3 3 0 Chain length determinant protein PadR PF03551.14 ACL96751.1 - 3e-10 39.9 0.0 5.8e-10 39.0 0.0 1.5 1 1 0 1 1 1 1 Transcriptional regulator PadR-like family HTH_34 PF13601.6 ACL96751.1 - 0.00045 20.3 0.0 0.00059 20.0 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_28 PF13518.6 ACL96751.1 - 0.011 15.8 0.2 0.28 11.3 0.0 2.3 1 1 1 2 2 2 0 Helix-turn-helix domain HicA_toxin PF07927.12 ACL96752.1 - 1.3e-22 79.6 0.1 1.4e-22 79.5 0.1 1.0 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, GntR PF00392.21 ACL96752.1 - 0.1 12.3 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HicB_lk_antitox PF15919.5 ACL96753.1 - 1.1e-43 148.2 0.0 1.2e-43 148.1 0.0 1.0 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system RHH_5 PF07878.11 ACL96753.1 - 0.00099 18.9 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 HicB-like_2 PF15970.5 ACL96753.1 - 0.0029 17.7 0.0 0.004 17.3 0.0 1.3 1 0 0 1 1 1 1 HicB_like antitoxin of bacterial toxin-antitoxin system RHH_1 PF01402.21 ACL96753.1 - 0.036 14.0 0.0 0.1 12.6 0.0 1.8 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family LAL_C2 PF18603.1 ACL96753.1 - 0.075 13.2 0.1 0.32 11.2 0.1 2.0 2 0 0 2 2 2 0 L-amino acid ligase C-terminal domain 2 DUF2199 PF09965.9 ACL96754.1 - 1.9e-28 99.4 0.0 2.2e-28 99.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2199) DegT_DnrJ_EryC1 PF01041.17 ACL96755.1 - 3.2e-13 49.8 1.7 1.2e-11 44.6 1.1 2.1 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family AMP-binding PF00501.28 ACL96756.2 - 1.1e-91 307.5 0.0 1.5e-91 307.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ACL96756.2 - 1.4e-17 64.4 1.3 3.4e-17 63.2 1.3 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3HCDH_N PF02737.18 ACL96757.1 - 1.2e-63 214.3 0.6 2.7e-63 213.1 0.6 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 ACL96757.1 - 3.8e-42 144.3 0.9 8.3e-42 143.2 0.9 1.7 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 ACL96757.1 - 6.1e-34 116.5 0.0 2e-20 73.2 0.0 3.4 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 ACL96757.1 - 3.4e-27 95.8 0.1 7.2e-27 94.7 0.1 1.6 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase NAD_binding_2 PF03446.15 ACL96757.1 - 4e-05 23.8 1.3 0.00014 22.1 1.3 1.9 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ACL96757.1 - 0.00071 20.1 3.1 0.0018 18.8 1.1 2.6 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 ACL96757.1 - 0.0076 16.5 0.6 0.15 12.3 0.1 2.6 2 0 0 2 2 2 1 TrkA-N domain Pyr_redox_2 PF07992.14 ACL96757.1 - 0.011 15.0 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 ACL96757.1 - 0.012 15.6 0.4 0.098 12.7 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 ACL96757.1 - 0.031 13.9 0.0 0.089 12.4 0.0 1.9 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DAO PF01266.24 ACL96757.1 - 0.052 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 ACL96757.1 - 0.079 13.5 0.4 0.23 12.0 0.4 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 ACL96757.1 - 0.084 13.3 0.1 0.21 12.0 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding IFS PF16718.5 ACL96757.1 - 0.19 11.8 0.0 0.39 10.8 0.0 1.4 1 0 0 1 1 1 0 Immunity factor for SPN Peptidase_S49 PF01343.18 ACL96757.1 - 0.21 11.5 0.6 2.4 8.1 0.1 2.7 2 1 1 3 3 3 0 Peptidase family S49 Beta-lactamase PF00144.24 ACL96758.2 - 9.8e-72 242.0 0.0 1.2e-71 241.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Rnf-Nqr PF02508.14 ACL96758.2 - 0.16 12.0 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Rnf-Nqr subunit, membrane protein HATPase_c PF02518.26 ACL96759.1 - 3.9e-26 91.8 0.2 1.2e-25 90.1 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ACL96759.1 - 5e-22 78.2 0.1 9.8e-22 77.2 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain PAS_3 PF08447.12 ACL96759.1 - 1e-19 70.6 0.5 1.1e-09 38.5 0.0 2.5 2 0 0 2 2 2 2 PAS fold HisKA PF00512.25 ACL96759.1 - 4.9e-19 68.1 0.1 1.6e-18 66.5 0.1 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 ACL96759.1 - 2.6e-09 37.3 0.0 7.4e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_11 PF14598.6 ACL96759.1 - 2.3e-08 34.1 0.0 0.011 15.9 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 ACL96759.1 - 3.3e-08 33.8 1.5 0.00019 21.6 0.1 2.5 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 ACL96759.1 - 5.4e-06 26.4 0.1 4e-05 23.6 0.0 2.4 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.7 ACL96759.1 - 0.00054 19.9 0.0 0.0016 18.4 0.0 1.8 1 0 0 1 1 1 1 PAS domain BRCT PF00533.26 ACL96759.1 - 0.073 13.5 0.0 0.18 12.2 0.0 1.6 2 0 0 2 2 1 0 BRCA1 C Terminus (BRCT) domain PAS_7 PF12860.7 ACL96759.1 - 0.17 12.1 0.0 0.79 9.9 0.0 2.2 3 0 0 3 3 3 0 PAS fold TetR_N PF00440.23 ACL96760.1 - 4.1e-25 87.3 0.6 5.6e-14 51.7 0.0 2.5 2 0 0 2 2 2 2 Bacterial regulatory proteins, tetR family TetR_C_24 PF17932.1 ACL96760.1 - 2.4e-06 27.8 0.1 0.00018 21.8 0.0 2.6 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain TetR_C_7 PF14246.6 ACL96760.1 - 0.0019 18.2 0.2 0.0051 16.8 0.0 1.8 2 0 0 2 2 2 1 AefR-like transcriptional repressor, C-terminal domain TetR_C_30 PF17939.1 ACL96760.1 - 0.018 15.3 1.9 1.5 9.0 0.1 3.6 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain TetR_C_27 PF17935.1 ACL96760.1 - 0.056 13.5 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HTH_23 PF13384.6 ACL96760.1 - 0.26 11.2 4.8 2.7 7.9 0.0 3.5 4 0 0 4 4 4 0 Homeodomain-like domain GA-like PF17573.2 ACL96761.1 - 4.9 7.1 7.3 3.6 7.6 1.1 3.4 3 0 0 3 3 3 0 GA-like domain TonB_dep_Rec PF00593.24 ACL96762.3 - 1e-42 147.6 20.6 1e-42 147.6 20.6 2.2 2 0 0 2 2 2 1 TonB dependent receptor Plug PF07715.15 ACL96762.3 - 2.6e-21 76.2 1.5 7e-21 74.8 1.5 1.8 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 ACL96762.3 - 2.2e-05 23.6 0.1 0.00024 20.2 0.0 2.2 2 0 0 2 2 2 1 Outer membrane protein beta-barrel family OEP PF02321.18 ACL96763.2 - 1.3e-35 122.9 30.8 2.4e-19 69.9 8.3 2.0 2 0 0 2 2 2 2 Outer membrane efflux protein HlyD_D23 PF16576.5 ACL96764.1 - 1e-23 83.7 0.4 1.5e-23 83.1 0.4 1.1 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 ACL96764.1 - 9.4e-17 61.7 1.6 3.8e-13 50.0 0.1 2.4 2 0 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 ACL96764.1 - 1.7e-07 30.9 1.0 1.7e-07 30.9 1.0 3.6 4 0 0 4 4 4 1 Biotin-lipoyl like Biotin_lipoyl PF00364.22 ACL96764.1 - 0.036 13.9 0.1 4.4 7.2 0.0 3.0 3 0 0 3 3 3 0 Biotin-requiring enzyme HlyD PF00529.20 ACL96764.1 - 3.8 7.4 14.6 72 3.4 14.6 2.5 1 1 0 1 1 1 0 HlyD membrane-fusion protein of T1SS ACR_tran PF00873.19 ACL96765.1 - 2.9e-244 813.2 14.9 3.4e-244 813.0 14.9 1.0 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 ACL96765.1 - 8.3e-09 34.8 46.1 1.7e-05 23.9 11.2 4.1 4 1 2 6 6 6 2 MMPL family SecD_SecF PF02355.16 ACL96765.1 - 3.5e-06 26.5 21.3 6.2e-06 25.7 8.0 2.4 2 0 0 2 2 2 2 Protein export membrane protein Patched PF02460.18 ACL96765.1 - 0.29 9.2 7.1 0.49 8.4 7.1 1.3 1 0 0 1 1 1 0 Patched family DUF2976 PF11190.8 ACL96765.1 - 0.33 10.8 7.0 9.7 6.1 0.1 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) DUF4118 PF13493.6 ACL96766.1 - 9.1e-19 67.2 8.3 1.6e-18 66.5 8.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4118) HisKA_2 PF07568.12 ACL96766.1 - 5.8e-14 51.9 0.0 1.2e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase HATPase_c_2 PF13581.6 ACL96766.1 - 1e-05 25.5 0.0 2.1e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 ACL96766.1 - 1.2e-05 25.8 0.0 3.7e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HWE_HK PF07536.14 ACL96766.1 - 0.0035 18.0 2.0 0.0064 17.2 0.2 2.1 2 0 0 2 2 2 1 HWE histidine kinase Rootletin PF15035.6 ACL96766.1 - 0.069 13.2 0.1 0.1 12.6 0.1 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion GTP_EFTU PF00009.27 ACL96767.1 - 3.9e-59 199.5 0.1 5.1e-59 199.1 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 ACL96767.1 - 1.3e-32 112.4 0.1 2.8e-32 111.4 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 ACL96767.1 - 1.8e-17 63.5 5.5 1.8e-17 63.5 5.5 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ACL96767.1 - 3e-05 24.1 0.0 6.7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 ACL96767.1 - 0.004 16.8 0.5 0.0071 16.0 0.0 1.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 ACL96767.1 - 0.027 14.4 0.1 0.091 12.7 0.0 1.8 1 1 0 1 1 1 0 RsgA GTPase GTP_EFTU PF00009.27 ACL96768.1 - 4.7e-71 238.3 0.0 6.6e-71 237.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 ACL96768.1 - 2.9e-42 143.3 0.0 5.8e-42 142.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 ACL96768.1 - 6.3e-30 103.1 0.0 1.3e-29 102.1 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 ACL96768.1 - 2.8e-29 101.0 0.2 7.6e-29 99.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ACL96768.1 - 1.1e-15 57.7 0.1 4.3e-15 55.9 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ACL96768.1 - 0.00035 20.6 0.1 0.00078 19.5 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 ACL96768.1 - 0.026 13.8 0.0 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 AIG1 family Porphobil_deamC PF03900.15 ACL96768.1 - 0.13 12.7 0.0 0.41 11.0 0.0 1.8 1 0 0 1 1 1 0 Porphobilinogen deaminase, C-terminal domain Ribosomal_S7 PF00177.21 ACL96769.1 - 1.2e-67 226.2 1.5 1.3e-67 226.0 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosom_S12_S23 PF00164.25 ACL96770.1 - 1.6e-39 134.1 0.8 1.8e-39 133.9 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DUF1772 PF08592.11 ACL96771.1 - 0.14 12.5 0.0 0.16 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Abhydrolase_1 PF00561.20 ACL96773.1 - 9e-15 55.0 0.0 6.3e-14 52.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ACL96773.1 - 2.6e-09 38.0 1.3 4.6e-09 37.2 1.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ACL96773.1 - 1.1e-06 28.1 0.0 3.8e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Torsin PF06309.11 ACL96773.1 - 0.0013 18.8 0.0 0.0023 18.1 0.0 1.3 1 0 0 1 1 1 1 Torsin Esterase PF00756.20 ACL96773.1 - 0.078 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative esterase NusG PF02357.19 ACL96774.1 - 2e-28 98.7 0.8 3.2e-28 98.1 0.3 1.6 2 0 0 2 2 2 1 Transcription termination factor nusG KOW PF00467.29 ACL96774.1 - 4.5e-07 29.6 0.7 1.9e-06 27.6 0.1 2.1 2 0 0 2 2 2 1 KOW motif SecE PF00584.20 ACL96775.1 - 3.5e-19 68.5 2.7 4.5e-19 68.1 2.7 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex NAD_binding_1 PF00175.21 ACL96778.3 - 9.3e-06 26.3 0.0 1.8e-05 25.3 0.0 1.5 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain MoeA_N PF03453.17 ACL96779.1 - 3.9e-36 124.2 1.8 6.3e-36 123.5 1.8 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 ACL96779.1 - 4.2e-19 68.6 0.0 6.2e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.15 ACL96779.1 - 1.4e-17 63.6 0.1 5.5e-17 61.7 0.0 2.1 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) FBPase_glpX PF03320.13 ACL96779.1 - 0.084 11.7 0.2 0.13 11.1 0.2 1.2 1 0 0 1 1 1 0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded Polysacc_synt_2 PF02719.15 ACL96780.1 - 6.4e-101 337.4 0.2 8.1e-101 337.0 0.2 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 ACL96780.1 - 7.1e-23 81.3 0.3 5.1e-22 78.5 0.3 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ACL96780.1 - 3.7e-17 62.3 0.2 5.1e-16 58.6 0.2 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 ACL96780.1 - 1.1e-16 61.1 0.0 2.4e-15 56.8 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ACL96780.1 - 4.7e-09 35.6 0.0 6.9e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ACL96780.1 - 3e-06 26.6 3.4 0.00068 18.9 0.8 2.6 2 1 1 3 3 3 2 Male sterility protein ThiF PF00899.21 ACL96780.1 - 7.7e-06 25.4 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 ThiF family adh_short PF00106.25 ACL96780.1 - 1e-05 25.1 0.1 1.9e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ACL96780.1 - 1.5e-05 25.0 0.2 3.7e-05 23.7 0.2 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ACL96780.1 - 0.065 13.1 1.2 0.14 12.1 1.2 1.5 1 0 0 1 1 1 0 NAD(P)H-binding Ldh_1_N PF00056.23 ACL96780.1 - 0.068 13.3 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DNA_pol3_alpha PF07733.12 ACL96781.1 - 2.9e-81 272.9 0.0 4.2e-81 272.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha NTPase domain DNA_pol3_finger PF17657.1 ACL96781.1 - 2.6e-54 183.0 0.0 4e-54 182.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial DNA polymerase III alpha subunit finger domain HHH_6 PF14579.6 ACL96781.1 - 1.9e-13 50.5 0.0 4.8e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif tRNA_anti-codon PF01336.25 ACL96781.1 - 8.3e-09 35.3 0.5 1.7e-08 34.3 0.5 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain PHP PF02811.19 ACL96781.1 - 2.1e-08 34.6 0.0 3.9e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 PHP domain tRNA_anti_2 PF13742.6 ACL96781.1 - 0.2 11.9 0.0 0.46 10.7 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain IMS PF00817.20 ACL96782.1 - 0.0015 18.5 0.0 0.0027 17.7 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family Carboxyl_trans PF01039.22 ACL96784.1 - 5.3e-79 266.1 0.0 7.3e-79 265.7 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 ACL96784.1 - 5.7e-47 159.9 0.0 1.1e-46 159.0 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ACL96784.1 - 3e-41 140.4 2.3 6.1e-41 139.4 0.3 2.4 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ACL96784.1 - 1.6e-33 115.1 0.0 2.2e-32 111.4 0.0 2.6 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 ACL96784.1 - 5.6e-13 48.5 0.2 1.2e-12 47.5 0.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 ACL96784.1 - 1.2e-09 37.8 0.6 0.00084 19.1 0.1 2.9 1 1 1 2 2 2 2 Biotin-lipoyl like LAL_C2 PF18603.1 ACL96784.1 - 0.0069 16.5 0.8 0.047 13.9 0.1 2.9 2 0 0 2 2 2 1 L-amino acid ligase C-terminal domain 2 HlyD_D23 PF16576.5 ACL96784.1 - 0.011 14.9 0.5 4.2 6.5 0.1 3.1 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp PF02222.22 ACL96784.1 - 0.013 15.1 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain RnfC_N PF13375.6 ACL96784.1 - 0.015 15.3 0.2 0.049 13.6 0.2 1.8 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain DUF3182 PF11379.8 ACL96784.1 - 0.029 13.3 0.1 0.07 12.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) HlyD_3 PF13437.6 ACL96784.1 - 0.06 14.1 2.8 14 6.5 0.1 3.2 3 0 0 3 3 3 0 HlyD family secretion protein TetR_C_24 PF17932.1 ACL96784.1 - 0.13 12.6 0.8 1.2 9.5 0.1 3.0 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain ATP-grasp_3 PF02655.14 ACL96784.1 - 0.2 11.7 0.0 0.46 10.5 0.0 1.6 1 1 0 1 1 1 0 ATP-grasp domain VanZ PF04892.12 ACL96785.2 - 2e-05 25.3 0.7 2.9e-05 24.7 0.7 1.3 1 1 0 1 1 1 1 VanZ like family DUF2809 PF10990.8 ACL96785.2 - 0.00017 22.2 0.8 0.003 18.2 0.2 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF2809) DUF998 PF06197.13 ACL96785.2 - 0.0023 17.6 5.7 0.0027 17.3 5.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF998) HupE_UreJ_2 PF13795.6 ACL96785.2 - 0.031 13.9 0.1 0.044 13.4 0.1 1.3 1 1 0 1 1 1 0 HupE / UreJ protein 2-Hacid_dh_C PF02826.19 ACL96786.1 - 1.7e-59 200.2 0.0 2.7e-59 199.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ACL96786.1 - 6.9e-38 129.3 0.7 2.5e-37 127.6 0.5 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 ACL96786.1 - 5.9e-06 26.0 0.1 2.2e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 ACT domain NAD_binding_2 PF03446.15 ACL96786.1 - 0.013 15.6 0.1 0.03 14.5 0.1 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 ACL96786.1 - 0.019 14.5 0.0 0.042 13.4 0.0 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 ACL96786.1 - 0.031 14.9 0.1 0.11 13.1 0.1 2.1 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Aminotran_5 PF00266.19 ACL96787.1 - 1.1e-09 37.7 0.0 1.3e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V EI24 PF07264.11 ACL96788.1 - 9.3e-05 22.7 1.3 0.00025 21.3 1.3 1.6 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) LA-virus_coat PF09220.10 ACL96788.1 - 0.099 11.3 0.3 0.13 10.8 0.3 1.2 1 0 0 1 1 1 0 L-A virus, major coat protein DUF2277 PF10041.9 ACL96789.1 - 0.33 11.3 3.1 0.74 10.2 3.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2277) HATPase_c PF02518.26 ACL96790.1 - 3.1e-30 105.0 0.0 5.8e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ACL96790.1 - 3.4e-24 85.2 0.3 7e-24 84.2 0.3 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ACL96790.1 - 6.9e-17 61.2 2.8 1.4e-16 60.3 0.4 2.8 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 ACL96790.1 - 0.00012 22.3 1.4 0.0025 18.1 0.4 2.8 2 0 0 2 2 2 1 HAMP domain CHASE8 PF17152.4 ACL96790.1 - 0.0028 17.8 1.6 0.018 15.3 1.6 2.4 1 1 0 1 1 1 1 Periplasmic sensor domain LAMTOR5 PF16672.5 ACL96790.1 - 0.036 14.0 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 HATPase_c_3 PF13589.6 ACL96790.1 - 0.059 13.2 0.4 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 ACL96790.1 - 0.18 11.7 0.0 0.43 10.5 0.0 1.7 1 0 0 1 1 1 0 GHKL domain DUF3995 PF13160.6 ACL96790.1 - 1.9 8.9 8.9 3.3 8.1 2.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) Peptidase_S8_N PF16361.5 ACL96791.1 - 0.0081 16.7 0.5 0.0094 16.4 0.5 1.2 1 0 0 1 1 1 1 N-terminal of Subtilase family LPAM_1 PF08139.12 ACL96791.1 - 0.12 13.0 0.8 0.17 12.4 0.8 1.3 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site DUF4148 PF13663.6 ACL96791.1 - 5.1 7.4 6.9 5.4 7.3 5.2 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4148) PhzC-PhzF PF02567.16 ACL96792.1 - 8.3e-51 173.1 0.0 2.9e-50 171.3 0.0 1.7 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein NTP_transf_6 PF06042.11 ACL96794.1 - 8.6e-50 168.7 0.0 9.8e-50 168.5 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyltransferase Phos_pyr_kin PF08543.12 ACL96795.1 - 2e-92 309.0 4.2 2.2e-92 308.9 4.2 1.0 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 ACL96795.1 - 1.1e-08 34.8 2.1 1.7e-08 34.2 2.1 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.17 ACL96795.1 - 0.28 10.6 9.8 0.58 9.6 9.8 1.6 1 1 0 1 1 1 0 Carbohydrate kinase Pterin_bind PF00809.22 ACL96796.1 - 1.8e-85 286.5 0.0 2.1e-85 286.3 0.0 1.0 1 0 0 1 1 1 1 Pterin binding enzyme DUF561 PF04481.12 ACL96796.1 - 0.085 12.0 0.2 0.25 10.5 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF561) HATPase_c PF02518.26 ACL96797.3 - 2.5e-19 69.8 0.0 4.1e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 ACL96797.3 - 4.2e-19 68.8 3.3 1.7e-08 34.6 0.0 2.8 3 0 0 3 3 3 2 PAS fold Response_reg PF00072.24 ACL96797.3 - 1.6e-16 60.4 0.1 4.8e-16 58.9 0.0 1.8 2 0 0 2 2 2 1 Response regulator receiver domain PAS_9 PF13426.7 ACL96797.3 - 8.7e-07 29.1 0.0 5.1e-05 23.5 0.0 2.4 2 0 0 2 2 2 1 PAS domain HisKA PF00512.25 ACL96797.3 - 9.2e-07 28.8 0.1 9.2e-07 28.8 0.1 2.2 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 ACL96797.3 - 0.0001 22.2 0.0 0.001 19.0 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 ACL96797.3 - 0.0022 18.0 0.0 0.13 12.3 0.0 3.0 2 1 0 2 2 2 1 PAS fold PAS_7 PF12860.7 ACL96797.3 - 0.022 14.9 0.1 1.3 9.2 0.0 3.1 3 0 0 3 3 3 0 PAS fold HPTransfase PF10090.9 ACL96797.3 - 0.025 14.4 0.0 0.072 12.9 0.0 1.7 1 0 0 1 1 1 0 Histidine phosphotransferase C-terminal domain HATPase_c_3 PF13589.6 ACL96797.3 - 0.033 14.0 0.0 0.07 13.0 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HEPN_SAV_6107 PF18726.1 ACL96797.3 - 0.5 10.9 4.5 9.1 6.9 0.1 3.0 2 0 0 2 2 2 0 SAV_6107-like HEPN Peptidase_M41 PF01434.18 ACL96798.1 - 3e-68 229.4 0.5 5.4e-68 228.6 0.5 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 ACL96798.1 - 2.8e-46 157.2 0.0 8e-46 155.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ACL96798.1 - 5.6e-17 61.3 0.0 1.4e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 ACL96798.1 - 4.8e-09 36.5 2.1 4.9e-09 36.5 0.4 1.9 2 0 0 2 2 2 1 FtsH Extracellular AAA_5 PF07728.14 ACL96798.1 - 1.7e-06 28.1 0.2 3.8e-05 23.7 0.0 3.3 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 ACL96798.1 - 6.9e-05 22.2 0.0 0.0002 20.7 0.0 1.7 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 ACL96798.1 - 0.00012 22.5 0.1 0.00067 20.1 0.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 ACL96798.1 - 0.00075 19.3 0.0 0.0037 17.0 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ACL96798.1 - 0.0014 18.9 0.2 0.11 12.8 0.1 3.2 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ACL96798.1 - 0.01 16.0 0.0 0.025 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 ACL96798.1 - 0.013 15.6 0.0 0.099 12.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 ACL96798.1 - 0.05 13.0 0.2 0.12 11.7 0.2 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 ACL96798.1 - 0.053 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Gemini_mov PF01708.16 ACL96798.1 - 0.063 13.1 0.1 68 3.3 0.0 3.2 3 0 0 3 3 3 0 Geminivirus putative movement protein AAA_7 PF12775.7 ACL96798.1 - 0.13 11.7 0.2 0.63 9.5 0.2 2.1 1 1 0 1 1 1 0 P-loop containing dynein motor region Myosin_N PF02736.19 ACL96798.1 - 0.16 11.8 0.1 0.33 10.8 0.1 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain ATP_bind_3 PF01171.20 ACL96799.1 - 1.2e-30 106.6 0.0 1.6e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 PP-loop family TPR_6 PF13174.6 ACL96800.1 - 1.1e-08 35.1 12.2 0.00013 22.4 0.1 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 ACL96800.1 - 1.3e-07 32.1 4.0 1.3e-07 32.1 4.0 3.4 2 2 0 3 3 2 1 Tetratricopeptide repeat YfiO PF13525.6 ACL96800.1 - 9.1e-07 28.8 1.7 3.1e-05 23.8 0.8 2.8 2 1 1 3 3 3 2 Outer membrane lipoprotein DUF3450 PF11932.8 ACL96800.1 - 0.00094 18.6 5.6 0.00094 18.6 5.6 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) TPR_19 PF14559.6 ACL96800.1 - 0.0016 18.9 11.2 0.013 15.9 0.1 3.2 2 2 1 3 3 2 2 Tetratricopeptide repeat TSKS PF15358.6 ACL96800.1 - 0.0021 16.5 0.4 0.0028 16.1 0.4 1.3 1 0 0 1 1 1 1 Testis-specific serine kinase substrate TolA_bind_tri PF16331.5 ACL96800.1 - 0.0026 17.8 6.0 0.0082 16.2 5.1 2.3 1 1 1 2 2 2 1 TolA binding protein trimerisation Tropomyosin PF00261.20 ACL96800.1 - 0.0026 17.2 2.8 0.0026 17.2 2.8 1.7 2 0 0 2 2 2 1 Tropomyosin HAUS-augmin3 PF14932.6 ACL96800.1 - 0.0036 16.9 2.4 0.0062 16.1 2.4 1.4 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 ANAPC3 PF12895.7 ACL96800.1 - 0.0049 17.1 0.4 0.23 11.7 0.1 2.6 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF3584 PF12128.8 ACL96800.1 - 0.0058 14.2 2.5 0.0078 13.8 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.12 ACL96800.1 - 0.0058 16.7 3.4 0.0058 16.7 3.4 1.8 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein Dynamitin PF04912.14 ACL96800.1 - 0.0072 15.7 1.1 0.012 15.0 1.1 1.3 1 0 0 1 1 1 1 Dynamitin Cast PF10174.9 ACL96800.1 - 0.01 14.1 2.0 0.015 13.6 2.0 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone MAD PF05557.13 ACL96800.1 - 0.013 13.9 1.1 0.017 13.6 1.1 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein FPP PF05911.11 ACL96800.1 - 0.019 13.2 0.8 0.026 12.8 0.8 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Fez1 PF06818.15 ACL96800.1 - 0.038 14.4 0.2 0.079 13.4 0.0 1.6 2 0 0 2 2 1 0 Fez1 Allexi_40kDa PF05549.11 ACL96800.1 - 0.041 13.4 0.1 0.09 12.3 0.0 1.5 2 0 0 2 2 1 0 Allexivirus 40kDa protein YPEB PF14620.6 ACL96800.1 - 0.044 13.1 0.7 0.069 12.5 0.7 1.2 1 0 0 1 1 1 0 YpeB sporulation STAT_alpha PF01017.20 ACL96800.1 - 0.053 13.4 3.2 0.053 13.4 1.9 1.6 2 0 0 2 2 1 0 STAT protein, all-alpha domain Uso1_p115_C PF04871.13 ACL96800.1 - 0.065 13.6 0.6 0.065 13.6 0.6 1.7 2 0 0 2 2 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Fmp27_WPPW PF10359.9 ACL96800.1 - 0.067 12.0 0.0 0.079 11.8 0.0 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain FlxA PF14282.6 ACL96800.1 - 0.072 13.1 7.0 0.22 11.5 7.0 1.7 1 1 0 1 1 1 0 FlxA-like protein Herpes_UL25 PF01499.16 ACL96800.1 - 0.077 11.5 2.4 0.12 10.9 2.4 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family TPR_14 PF13428.6 ACL96800.1 - 0.077 13.9 0.2 0.077 13.9 0.2 4.1 3 1 1 4 4 3 0 Tetratricopeptide repeat SlyX PF04102.12 ACL96800.1 - 0.11 13.1 11.9 1.3 9.6 9.1 3.1 3 1 0 3 3 2 0 SlyX Laminin_II PF06009.12 ACL96800.1 - 0.11 12.4 4.5 0.21 11.6 3.8 1.7 1 1 0 1 1 1 0 Laminin Domain II FemAB PF02388.16 ACL96800.1 - 0.13 11.1 0.3 0.18 10.7 0.3 1.2 1 0 0 1 1 1 0 FemAB family PilJ PF13675.6 ACL96800.1 - 0.14 12.2 10.0 1.9 8.5 7.9 2.9 2 1 0 2 2 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term ABC_tran_CTD PF16326.5 ACL96800.1 - 0.14 12.4 8.2 1.5 9.2 2.0 2.9 2 1 1 3 3 2 0 ABC transporter C-terminal domain Tropomyosin_1 PF12718.7 ACL96800.1 - 0.15 12.3 4.3 0.11 12.7 2.4 1.7 2 0 0 2 2 1 0 Tropomyosin like HSBP1 PF06825.12 ACL96800.1 - 0.18 11.7 1.2 28 4.6 0.0 3.0 3 0 0 3 3 3 0 Heat shock factor binding protein 1 DUF5320 PF17253.2 ACL96800.1 - 0.18 12.9 1.6 22 6.2 0.7 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5320) T3SSipB PF16535.5 ACL96800.1 - 0.22 12.0 8.9 0.18 12.2 6.0 2.1 2 0 0 2 2 2 0 Type III cell invasion protein SipB Syntaxin PF00804.25 ACL96800.1 - 0.23 11.1 2.9 0.13 12.0 0.4 1.7 2 0 0 2 2 2 0 Syntaxin TPR_2 PF07719.17 ACL96800.1 - 0.34 11.1 4.7 5.7 7.3 0.7 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat APG6_N PF17675.1 ACL96800.1 - 0.36 11.4 4.9 0.82 10.2 4.9 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region ATG16 PF08614.11 ACL96800.1 - 0.38 10.9 9.3 0.039 14.2 4.1 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) NPV_P10 PF05531.12 ACL96800.1 - 0.41 11.1 1.7 5.8 7.5 1.9 2.4 2 1 0 2 2 1 0 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.9 ACL96800.1 - 0.41 10.7 4.2 0.17 11.9 1.7 1.6 2 0 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.8 ACL96800.1 - 0.42 10.6 3.2 1.2 9.2 3.2 1.8 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding BLOC1_2 PF10046.9 ACL96800.1 - 0.64 10.4 5.4 20 5.6 0.1 3.3 3 1 0 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Seryl_tRNA_N PF02403.22 ACL96800.1 - 0.98 9.7 5.0 2.6 8.3 5.0 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain CLZ PF16526.5 ACL96800.1 - 1.8 8.9 9.3 3.2 8.2 0.4 3.1 3 1 1 4 4 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels XhlA PF10779.9 ACL96800.1 - 2.1 8.6 8.2 0.67 10.2 1.3 2.9 3 1 1 4 4 2 0 Haemolysin XhlA DUF4407 PF14362.6 ACL96800.1 - 3.7 6.8 12.0 0.96 8.7 8.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) MerR-DNA-bind PF09278.11 ACL96800.1 - 4 8.0 14.5 4 8.0 3.5 3.4 3 1 0 4 4 4 0 MerR, DNA binding OmpA PF00691.20 ACL96801.1 - 1.6e-20 73.3 0.1 2.2e-20 72.9 0.1 1.2 1 0 0 1 1 1 1 OmpA family PD40 PF07676.12 ACL96802.1 - 8.9e-37 124.3 19.7 5.2e-13 48.6 0.6 6.0 6 0 0 6 6 6 4 WD40-like Beta Propeller Repeat TolB_N PF04052.13 ACL96802.1 - 1.7e-29 102.1 0.0 2.7e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 TolB amino-terminal domain DPPIV_N PF00930.21 ACL96802.1 - 5.1e-10 38.7 0.0 0.0073 15.1 0.0 4.1 2 1 2 4 4 4 3 Dipeptidyl peptidase IV (DPP IV) N-terminal region Pectate_lyase22 PF14583.6 ACL96802.1 - 1.1e-06 27.6 0.0 0.073 11.7 0.0 3.6 2 1 2 4 4 4 3 Oligogalacturonate lyase DUF5050 PF16472.5 ACL96802.1 - 0.00073 18.9 0.0 0.0028 17.0 0.0 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF5050) Gmad1 PF10647.9 ACL96802.1 - 0.0012 18.6 0.1 0.15 11.8 0.0 3.0 2 1 1 3 3 3 1 Lipoprotein LpqB beta-propeller domain Peptidase_S9_N PF02897.15 ACL96802.1 - 0.18 10.6 0.0 1 8.1 0.0 1.9 1 1 1 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain TonB_2 PF13103.6 ACL96803.1 - 0.043 14.1 2.0 0.073 13.3 0.0 2.3 2 0 0 2 2 2 0 TonB C terminal Gly_kinase PF02595.15 ACL96803.1 - 0.085 11.8 0.1 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 Glycerate kinase family ORC6 PF05460.13 ACL96803.1 - 0.39 9.9 7.1 0.46 9.7 7.1 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF1631 PF07793.11 ACL96803.1 - 3.5 5.9 9.2 4.5 5.6 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) PRCC PF10253.9 ACL96803.1 - 4.4 8.0 12.6 7.9 7.2 12.6 1.5 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Ndc1_Nup PF09531.10 ACL96803.1 - 8.9 4.9 5.7 9.2 4.8 5.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ExbD PF02472.16 ACL96804.1 - 2e-28 99.2 0.0 2.3e-28 99.0 0.0 1.0 1 0 0 1 1 1 1 Biopolymer transport protein ExbD/TolR DUF2149 PF09919.9 ACL96804.1 - 0.045 14.0 0.0 0.084 13.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) MotA_ExbB PF01618.16 ACL96805.1 - 2.2e-35 121.2 0.8 3.5e-35 120.5 0.8 1.4 1 0 0 1 1 1 1 MotA/TolQ/ExbB proton channel family 4HBT PF03061.22 ACL96806.1 - 1e-14 54.6 0.8 1.4e-14 54.2 0.8 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 ACL96806.1 - 1.6e-09 38.3 0.0 2.1e-09 37.9 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily AfsA PF03756.13 ACL96806.1 - 0.0012 18.9 0.2 0.0018 18.3 0.2 1.3 1 0 0 1 1 1 1 A-factor biosynthesis hotdog domain FTSW_RODA_SPOVE PF01098.19 ACL96807.1 - 0.00021 20.4 6.7 0.00047 19.2 6.7 1.6 1 1 0 1 1 1 1 Cell cycle protein RuvB_N PF05496.12 ACL96808.1 - 2.8e-79 264.4 0.0 4.1e-79 263.9 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_4 PF17864.1 ACL96808.1 - 4.9e-26 90.3 1.4 8.8e-26 89.5 1.4 1.4 1 0 0 1 1 1 1 RuvB AAA lid domain RuvB_C PF05491.13 ACL96808.1 - 7.8e-26 89.7 0.0 1.3e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 RuvB C-terminal winged helix domain AAA PF00004.29 ACL96808.1 - 2e-19 70.3 0.0 3.8e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ACL96808.1 - 3.4e-09 36.8 0.4 1.2e-06 28.5 0.4 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 ACL96808.1 - 1.4e-06 27.9 0.5 0.0012 18.3 0.1 2.6 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 ACL96808.1 - 1.7e-06 27.5 0.3 0.0001 21.7 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_22 PF13401.6 ACL96808.1 - 1.2e-05 25.6 0.7 0.023 15.0 0.0 3.1 2 1 1 3 3 3 1 AAA domain AAA_3 PF07726.11 ACL96808.1 - 7.3e-05 22.6 0.0 0.0057 16.5 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ACL96808.1 - 0.00014 22.3 2.3 0.0026 18.2 0.1 2.7 2 1 0 3 3 3 1 AAA ATPase domain Sigma54_activat PF00158.26 ACL96808.1 - 0.00018 21.2 0.0 0.16 11.7 0.0 2.2 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_18 PF13238.6 ACL96808.1 - 0.00027 21.5 0.0 0.00051 20.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 ACL96808.1 - 0.0011 19.0 0.0 0.0016 18.4 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain TsaE PF02367.17 ACL96808.1 - 0.0013 18.7 0.0 0.0027 17.7 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 ACL96808.1 - 0.0016 17.6 0.0 0.12 11.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 ACL96808.1 - 0.0019 18.2 0.0 0.0037 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 ACL96808.1 - 0.0021 18.0 0.1 0.051 13.5 0.0 2.2 2 0 0 2 2 2 1 NTPase AAA_33 PF13671.6 ACL96808.1 - 0.0038 17.4 0.0 0.01 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain MCM PF00493.23 ACL96808.1 - 0.012 14.8 0.0 0.92 8.6 0.0 2.4 1 1 0 1 1 1 0 MCM P-loop domain RNA_helicase PF00910.22 ACL96808.1 - 0.013 15.9 0.0 0.021 15.2 0.0 1.3 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 ACL96808.1 - 0.015 15.1 1.3 0.17 11.6 0.2 2.7 2 1 0 2 2 2 0 IstB-like ATP binding protein NB-ARC PF00931.22 ACL96808.1 - 0.018 14.2 0.0 0.15 11.3 0.0 2.2 3 0 0 3 3 3 0 NB-ARC domain Bac_DnaA PF00308.18 ACL96808.1 - 0.019 14.8 0.0 0.58 10.0 0.0 2.1 2 0 0 2 2 2 0 Bacterial dnaA protein ResIII PF04851.15 ACL96808.1 - 0.03 14.3 0.0 1 9.3 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NACHT PF05729.12 ACL96808.1 - 0.036 14.0 0.0 0.098 12.6 0.0 1.7 2 0 0 2 2 1 0 NACHT domain AAA_17 PF13207.6 ACL96808.1 - 0.037 14.4 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ACL96808.1 - 0.055 13.2 0.0 0.11 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_2 PF07724.14 ACL96808.1 - 0.056 13.5 0.0 1.7 8.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.6 ACL96808.1 - 0.057 13.5 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 ACL96808.1 - 0.13 12.7 0.0 0.25 11.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 ACL96808.1 - 0.15 11.6 1.2 0.36 10.4 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 ACL96808.1 - 0.15 12.4 0.7 2.1 8.6 0.1 2.5 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.6 ACL96808.1 - 0.15 12.3 0.3 0.53 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Phage_TAC_6 PF09550.10 ACL96808.1 - 0.49 10.9 3.5 4.2 7.9 0.1 3.4 3 0 0 3 3 3 0 Phage tail assembly chaperone protein, TAC RuvA_N PF01330.21 ACL96809.1 - 5.1e-14 52.1 0.0 1.5e-13 50.6 0.0 1.8 2 0 0 2 2 2 1 RuvA N terminal domain HHH_5 PF14520.6 ACL96809.1 - 2.9e-12 47.0 2.7 1.4e-11 44.8 0.4 3.1 4 1 0 4 4 4 1 Helix-hairpin-helix domain RuvA_C PF07499.13 ACL96809.1 - 2.4e-09 37.5 4.3 8.1e-09 35.8 4.3 2.0 1 0 0 1 1 1 1 RuvA, C-terminal domain HHH PF00633.23 ACL96809.1 - 0.0048 16.7 3.5 0.39 10.7 0.1 3.6 3 0 0 3 3 3 2 Helix-hairpin-helix motif DNA_pol_lambd_f PF10391.9 ACL96809.1 - 0.21 11.4 0.1 31 4.5 0.0 3.3 3 0 0 3 3 3 0 Fingers domain of DNA polymerase lambda HHH_2 PF12826.7 ACL96809.1 - 0.28 11.3 2.8 5.6 7.1 0.0 3.7 5 0 0 5 5 5 0 Helix-hairpin-helix motif RuvC PF02075.17 ACL96810.1 - 1.6e-43 148.1 0.1 1.9e-43 147.9 0.1 1.0 1 0 0 1 1 1 1 Crossover junction endodeoxyribonuclease RuvC DnaB_bind PF10410.9 ACL96810.1 - 0.088 13.0 0.1 0.81 9.9 0.0 2.4 3 0 0 3 3 3 0 DnaB-helicase binding domain of primase Peptidase_M20 PF01546.28 ACL96811.1 - 7e-37 127.1 0.0 1.3e-36 126.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ACL96811.1 - 3.2e-19 68.8 0.0 5.3e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 ACL96811.1 - 1.9e-05 24.5 0.0 8.7e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M28 Peripla_BP_1 PF00532.21 ACL96811.1 - 0.00061 19.3 0.1 0.021 14.3 0.0 2.2 2 0 0 2 2 2 1 Periplasmic binding proteins and sugar binding domain of LacI family CHAP PF05257.16 ACL96812.1 - 0.00045 20.8 0.2 0.0008 19.9 0.2 1.4 1 0 0 1 1 1 1 CHAP domain DUF2272 PF10030.9 ACL96812.1 - 0.001 18.9 0.0 1.6 8.5 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2272) SAICAR_synt PF01259.18 ACL96815.1 - 2e-80 270.0 0.0 2.4e-80 269.8 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase Transcrip_reg PF01709.20 ACL96816.1 - 2.8e-88 295.4 1.1 3.2e-88 295.2 1.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator YmdB PF13277.6 ACL96817.1 - 1.5e-97 325.9 0.0 1.8e-97 325.7 0.0 1.0 1 0 0 1 1 1 1 YmdB-like protein PGA_cap PF09587.10 ACL96817.1 - 0.023 14.1 0.5 4.9 6.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial capsule synthesis protein PGA_cap 5-FTHF_cyc-lig PF01812.20 ACL96818.1 - 2.9e-28 99.0 0.0 3.4e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Peptidase_S9 PF00326.21 ACL96819.1 - 2.2e-35 122.1 0.2 3.9e-35 121.3 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 ACL96819.1 - 6e-12 45.7 0.9 8.1e-10 38.7 0.7 2.6 2 1 1 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 ACL96819.1 - 2.1e-10 40.5 0.5 8.7e-10 38.5 0.1 2.2 2 1 0 2 2 2 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 ACL96819.1 - 2.2e-10 40.2 0.1 4.1e-05 23.0 0.1 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ACL96819.1 - 8.5e-08 33.1 3.6 8.5e-08 33.1 3.6 3.1 3 1 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ACL96819.1 - 2.3e-07 30.7 0.3 1.8e-06 27.8 0.4 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.12 ACL96819.1 - 2.8e-06 26.3 0.0 0.00021 20.1 0.0 2.2 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 ACL96819.1 - 2.3e-05 24.4 0.1 0.0004 20.3 0.1 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 ACL96819.1 - 2.5e-05 24.1 0.0 6.6e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 ACL96819.1 - 0.00057 19.7 0.0 0.021 14.7 0.0 2.2 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase LIP PF03583.14 ACL96819.1 - 0.0075 15.6 0.4 0.64 9.3 0.8 2.6 3 0 0 3 3 3 1 Secretory lipase DUF1100 PF06500.11 ACL96819.1 - 0.076 11.8 0.0 0.16 10.7 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) ZapA PF05164.13 ACL96820.1 - 4.5e-21 75.1 0.8 5.9e-21 74.7 0.8 1.2 1 0 0 1 1 1 1 Cell division protein ZapA DUF4164 PF13747.6 ACL96821.1 - 1.1e-05 25.6 14.0 0.00016 21.9 14.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4164) PUL PF08324.11 ACL96821.1 - 0.009 15.3 3.1 0.01 15.1 3.1 1.0 1 0 0 1 1 1 1 PUL domain Gp_dh_C PF02800.20 ACL96822.1 - 1.1e-58 197.3 0.0 2e-58 196.5 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 ACL96822.1 - 4.8e-34 116.7 0.0 9.6e-34 115.8 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 ACL96822.1 - 0.081 13.6 0.1 0.45 11.2 0.1 2.3 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 ACL96822.1 - 0.085 12.8 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PGK PF00162.19 ACL96823.1 - 1.5e-139 465.2 0.1 1.7e-139 465.0 0.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase F_bP_aldolase PF01116.20 ACL96824.1 - 5.9e-91 304.8 0.2 7.1e-91 304.6 0.2 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II NrsF PF06532.11 ACL96826.1 - 5e-62 209.3 27.2 5.6e-62 209.1 27.2 1.0 1 0 0 1 1 1 1 Negative regulator of sigma F YhhN PF07947.14 ACL96826.1 - 0.012 15.3 0.3 0.012 15.3 0.3 2.5 2 1 0 2 2 2 0 YhhN family 5TM-5TMR_LYT PF07694.12 ACL96826.1 - 1 8.8 12.4 4 6.9 9.9 2.6 2 1 0 2 2 2 0 5TMR of 5TMR-LYT Sigma70_r2 PF04542.14 ACL96827.2 - 2.7e-14 52.7 1.1 2.7e-14 52.7 1.1 1.7 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 ACL96827.2 - 1.1e-10 40.9 0.2 1.8e-10 40.2 0.2 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 ACL96827.2 - 1.6e-10 40.5 0.8 3.4e-10 39.4 0.8 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 ACL96827.2 - 4.5e-07 29.9 0.8 6.8e-07 29.3 0.8 1.4 1 1 0 1 1 1 1 ECF sigma factor DUF2282 PF10048.9 ACL96828.1 - 6.2e-25 87.0 7.4 1e-24 86.3 7.4 1.4 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2282) DUF692 PF05114.13 ACL96829.1 - 2.3e-97 325.3 0.0 2.6e-97 325.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF692) DUF2063 PF09836.9 ACL96830.1 - 3.2e-22 78.6 0.0 7.5e-22 77.4 0.0 1.7 2 0 0 2 2 2 1 Putative DNA-binding domain DoxX PF07681.12 ACL96831.1 - 2.1e-18 66.7 6.6 2.2e-18 66.6 5.3 1.7 2 0 0 2 2 2 1 DoxX DoxD PF04173.13 ACL96831.1 - 0.00016 21.6 0.8 0.00071 19.5 0.2 2.0 2 0 0 2 2 2 1 TQO small subunit DoxD Response_reg PF00072.24 ACL96832.1 - 1.6e-10 41.1 0.0 2.1e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain RCC_reductase PF06405.11 ACL96832.1 - 0.11 11.7 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Red chlorophyll catabolite reductase (RCC reductase) Hpt PF01627.23 ACL96833.1 - 0.0001 22.5 3.1 0.00017 21.8 3.0 1.5 1 1 0 1 1 1 1 Hpt domain DUF410 PF04190.13 ACL96833.1 - 0.018 14.9 0.0 0.023 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF410) TspO_MBR PF03073.15 ACL96834.2 - 4.2e-06 26.9 0.5 5.4e-06 26.5 0.5 1.2 1 0 0 1 1 1 1 TspO/MBR family Acetyltransf_1 PF00583.25 ACL96835.1 - 1.8e-10 41.1 0.0 2.3e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ACL96835.1 - 2.5e-05 24.6 0.0 3.7e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ACL96835.1 - 3.3e-05 23.8 0.0 4.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 ACL96835.1 - 0.0024 18.0 1.0 0.0056 16.8 0.2 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ACL96835.1 - 0.0034 17.5 0.0 0.0054 16.8 0.0 1.2 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Ferritin PF00210.24 ACL96836.1 - 1.2e-34 119.3 0.1 1.3e-34 119.2 0.1 1.0 1 0 0 1 1 1 1 Ferritin-like domain Fer2_BFD PF04324.15 ACL96837.1 - 3.9e-09 36.7 7.0 4.6e-09 36.5 7.0 1.1 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain TMP-TENI PF02581.17 ACL96838.1 - 3.8e-52 176.3 0.1 4.4e-52 176.0 0.1 1.1 1 0 0 1 1 1 1 Thiamine monophosphate synthase QRPTase_C PF01729.19 ACL96838.1 - 0.008 16.0 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain Sigma70_r2 PF04542.14 ACL96840.1 - 1.3e-14 53.7 1.6 4.5e-14 52.0 1.6 1.9 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 ACL96840.1 - 8e-14 51.1 0.1 2e-13 49.8 0.1 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.16 ACL96840.1 - 4.9e-06 26.0 0.2 1e-05 24.9 0.2 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 SnoaL_2 PF12680.7 ACL96840.1 - 5.2e-06 27.0 0.7 9.3e-06 26.2 0.2 1.7 2 0 0 2 2 2 1 SnoaL-like domain DUF4440 PF14534.6 ACL96840.1 - 0.025 15.0 0.0 0.062 13.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) CMD PF02627.20 ACL96841.1 - 0.033 14.2 0.7 0.033 14.2 0.7 1.9 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family DUF1206 PF06724.11 ACL96841.1 - 3.9 7.6 7.7 7.6 6.7 2.3 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) DUF4345 PF14248.6 ACL96842.1 - 0.012 15.5 9.8 0.014 15.3 8.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4345) Inositol_P PF00459.25 ACL96843.2 - 4.3e-59 200.3 0.1 4.7e-59 200.1 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family HTH_26 PF13443.6 ACL96844.1 - 6.2e-21 74.6 0.0 7.2e-21 74.4 0.0 1.0 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_3 PF01381.22 ACL96844.1 - 2.3e-05 24.3 0.0 3.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_37 PF13744.6 ACL96844.1 - 0.00048 20.0 0.0 0.00059 19.7 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 ACL96844.1 - 0.0043 17.0 0.0 0.0055 16.7 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 ACL96844.1 - 0.023 15.1 0.0 0.027 14.8 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_10 PF04967.12 ACL96844.1 - 0.058 13.2 0.0 0.093 12.5 0.0 1.3 1 0 0 1 1 1 0 HTH DNA binding domain DUF2122 PF09895.9 ACL96844.1 - 0.068 13.6 0.0 0.086 13.2 0.0 1.2 1 0 0 1 1 1 0 RecB-family nuclease (DUF2122) DUF2975 PF11188.8 ACL96845.1 - 1.1e-06 28.5 7.6 1.1e-05 25.3 2.9 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2975) GDPD PF03009.17 ACL96846.2 - 4.2e-50 170.9 0.0 4.8e-50 170.7 0.0 1.0 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF885 PF05960.11 ACL96847.2 - 0.0087 15.8 5.9 0.84 9.2 0.2 3.0 2 1 1 3 3 3 3 Bacterial protein of unknown function (DUF885) ABC_membrane PF00664.23 ACL96848.1 - 4.7e-47 160.9 8.6 6e-47 160.6 8.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 ACL96848.1 - 1.7e-33 116.0 0.0 2.9e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ACL96848.1 - 9.9e-09 34.9 0.3 1e-06 28.3 0.1 2.2 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ACL96848.1 - 2e-06 28.3 0.6 6e-06 26.7 0.6 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ACL96848.1 - 0.00011 22.4 0.0 0.00077 19.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 ACL96848.1 - 0.00037 19.8 0.1 0.006 15.9 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_21 PF13304.6 ACL96848.1 - 0.0014 18.5 0.1 0.03 14.1 0.0 2.3 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 ACL96848.1 - 0.0019 17.9 0.6 0.013 15.2 0.6 2.3 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 ACL96848.1 - 0.0025 16.7 0.3 0.0066 15.3 0.1 1.7 2 1 0 2 2 2 1 Predicted ATPase of the ABC class AAA PF00004.29 ACL96848.1 - 0.0026 18.2 0.0 0.044 14.2 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 ACL96848.1 - 0.0031 17.2 0.0 0.008 15.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ACL96848.1 - 0.013 15.4 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 ACL96848.1 - 0.018 15.1 0.0 0.16 11.9 0.0 2.3 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 ACL96848.1 - 0.02 15.0 0.0 0.045 13.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ACL96848.1 - 0.07 13.7 0.0 0.19 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 ACL96848.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase MMR_HSR1 PF01926.23 ACL96848.1 - 0.13 12.4 0.0 0.35 11.0 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Rad17 PF03215.15 ACL96848.1 - 0.21 11.5 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Ribosomal_L31 PF01197.18 ACL96849.1 - 4.6e-24 84.4 0.0 5.4e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L31 CxxCxxCC PF03692.15 ACL96850.1 - 3.8e-09 37.1 7.8 6.9e-09 36.3 7.8 1.4 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain ZZ PF00569.17 ACL96850.1 - 0.52 10.2 6.7 3 7.7 1.2 2.5 2 1 0 2 2 2 0 Zinc finger, ZZ type PBP_N PF17093.5 ACL96851.1 - 2.7e-84 280.3 10.5 2.7e-84 280.3 10.5 2.0 2 0 0 2 2 2 1 Penicillin-binding protein N-terminus Transgly PF00912.22 ACL96851.1 - 7.2e-61 204.7 0.2 1.8e-60 203.5 0.0 1.7 2 0 0 2 2 2 1 Transglycosylase Transpeptidase PF00905.22 ACL96851.1 - 5.7e-34 117.7 0.2 3.8e-33 115.0 0.2 2.0 1 1 0 1 1 1 1 Penicillin binding protein transpeptidase domain Asp_Glu_race PF01177.22 ACL96852.2 - 2.1e-57 194.5 0.0 2.4e-57 194.4 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Pantoate_transf PF02548.15 ACL96852.2 - 0.0025 17.2 0.1 0.092 12.1 0.0 2.1 2 0 0 2 2 2 2 Ketopantoate hydroxymethyltransferase AroM PF07302.11 ACL96852.2 - 0.019 14.4 0.1 3.1 7.1 0.0 2.4 2 1 0 2 2 2 0 AroM protein ABC2_membrane_4 PF12730.7 ACL96853.1 - 8.5e-16 58.4 7.9 8.5e-16 58.4 7.9 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein DUF3361 PF11841.8 ACL96853.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) ABC2_membrane_2 PF12679.7 ACL96853.1 - 1.8 7.8 19.8 5.4 6.2 19.7 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein ABC_tran PF00005.27 ACL96854.1 - 2.8e-27 95.9 0.0 4.1e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ACL96854.1 - 5.5e-12 46.1 0.2 1.9e-07 31.2 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 ACL96854.1 - 0.0087 15.8 0.0 0.027 14.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ACL96854.1 - 0.12 12.7 0.1 14 6.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 ACL96854.1 - 0.13 12.1 0.5 0.26 11.0 0.5 1.5 1 1 0 1 1 1 0 MukB N-terminal SRP54 PF00448.22 ACL96854.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 ACL96854.1 - 0.22 12.0 0.0 0.33 11.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF2975 PF11188.8 ACL96855.1 - 1.1e-05 25.3 0.8 1.1e-05 25.3 0.8 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2975) P5-ATPase PF12409.8 ACL96855.1 - 2 8.5 4.0 0.97 9.5 1.9 1.5 1 1 1 2 2 2 0 P5-type ATPase cation transporter HTH_26 PF13443.6 ACL96856.1 - 3.9e-18 65.7 0.0 4.7e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_3 PF01381.22 ACL96856.1 - 1.3e-05 25.1 0.0 1.5e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 ACL96856.1 - 0.00015 22.0 0.1 0.00018 21.7 0.1 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 ACL96856.1 - 0.00051 19.9 0.0 0.00069 19.5 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 ACL96856.1 - 0.0013 18.7 0.0 0.0017 18.3 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain ATP-grasp PF02222.22 ACL96857.1 - 6.6e-54 182.0 0.0 1.1e-53 181.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 ACL96857.1 - 1.3e-15 56.8 0.1 2.7e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain 2-Hacid_dh_C PF02826.19 ACL96857.1 - 0.00056 19.3 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CPSase_L_D2 PF02786.17 ACL96857.1 - 0.00085 18.9 0.0 0.097 12.2 0.1 2.2 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain 3HCDH_N PF02737.18 ACL96857.1 - 0.0027 17.6 0.0 0.0057 16.6 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 ACL96857.1 - 0.0044 17.5 1.5 0.1 13.1 0.1 2.7 2 1 0 2 2 2 1 XdhC Rossmann domain PALP PF00291.25 ACL96857.1 - 0.0065 15.9 0.6 0.022 14.2 0.0 1.9 1 1 1 2 2 2 1 Pyridoxal-phosphate dependent enzyme F420_oxidored PF03807.17 ACL96857.1 - 0.048 14.3 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 ACL96857.1 - 0.054 13.7 0.0 0.13 12.4 0.0 1.7 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AIRC PF00731.20 ACL96858.1 - 3e-64 215.1 1.7 3.4e-64 214.9 1.7 1.0 1 0 0 1 1 1 1 AIR carboxylase GGDEF PF00990.21 ACL96859.1 - 2.4e-38 131.4 0.0 3.2e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Response_reg PF00072.24 ACL96860.1 - 1.3e-15 57.6 0.0 1.6e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Peptidase_M61 PF05299.12 ACL96861.1 - 3.1e-10 40.5 0.5 8.5e-10 39.1 0.5 1.7 1 1 0 1 1 1 1 M61 glycyl aminopeptidase Peptidase_M61_N PF17899.1 ACL96861.1 - 0.00056 20.0 0.0 0.0065 16.6 0.0 2.2 1 1 0 1 1 1 1 Peptidase M61 N-terminal domain DUF465 PF04325.13 ACL96862.2 - 1.3e-14 53.9 7.7 2.2e-14 53.2 7.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF465) LRRFIP PF09738.9 ACL96862.2 - 0.0041 16.6 0.4 0.0045 16.5 0.4 1.0 1 0 0 1 1 1 1 LRRFIP family DUF5595 PF18077.1 ACL96862.2 - 0.022 14.8 3.0 0.49 10.5 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5595) DUF3422 PF11902.8 ACL96862.2 - 0.044 12.9 0.2 0.052 12.7 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3422) Syntaxin-6_N PF09177.11 ACL96862.2 - 0.074 13.6 0.4 0.077 13.6 0.4 1.2 1 0 0 1 1 1 0 Syntaxin 6, N-terminal DivIC PF04977.15 ACL96862.2 - 0.17 11.6 2.3 6.7 6.6 0.1 2.0 1 1 1 2 2 2 0 Septum formation initiator DUF4140 PF13600.6 ACL96862.2 - 1.7 9.1 4.9 3.3 8.2 0.9 2.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) PspB PF06667.12 ACL96862.2 - 2.5 8.2 4.7 5.1 7.2 0.3 2.0 1 1 1 2 2 2 0 Phage shock protein B DUF2390 PF09523.10 ACL96863.1 - 4.3e-30 104.2 0.1 6.3e-30 103.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2390) Flavoprotein PF02441.19 ACL96864.1 - 6.6e-22 77.9 0.1 8.5e-22 77.6 0.1 1.1 1 0 0 1 1 1 1 Flavoprotein DUF465 PF04325.13 ACL96865.2 - 2.1e-13 50.1 1.6 2.5e-13 49.9 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF465) ABC_tran_CTD PF16326.5 ACL96865.2 - 0.007 16.6 0.3 0.011 16.0 0.3 1.3 1 1 0 1 1 1 1 ABC transporter C-terminal domain PKcGMP_CC PF16808.5 ACL96865.2 - 9.3 6.2 11.6 4.4 7.2 0.8 2.3 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF1013 PF06242.11 ACL96866.1 - 1.6e-60 203.2 0.1 2.6e-60 202.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1013) HTH_23 PF13384.6 ACL96866.1 - 0.0018 18.0 0.0 0.88 9.4 0.1 2.5 2 0 0 2 2 2 2 Homeodomain-like domain Phage_terminase PF10668.9 ACL96866.1 - 0.064 13.3 0.0 0.25 11.4 0.0 1.9 2 0 0 2 2 2 0 Phage terminase small subunit HTH_Tnp_ISL3 PF13542.6 ACL96866.1 - 0.12 11.8 0.0 0.53 9.7 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 ADH_zinc_N_2 PF13602.6 ACL96867.1 - 3.7e-26 92.8 1.5 5e-26 92.3 0.6 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ACL96867.1 - 3.8e-24 85.1 3.0 6.3e-24 84.4 3.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ACL96867.1 - 2.2e-07 30.8 0.0 2e-05 24.4 0.0 2.6 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 ACL96867.1 - 0.035 13.4 4.1 0.062 12.6 4.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 ACL96867.1 - 0.16 11.4 7.0 0.082 12.3 3.8 2.0 1 1 1 2 2 2 0 short chain dehydrogenase NAD_binding_10 PF13460.6 ACL96867.1 - 0.39 10.6 6.1 0.59 10.0 5.5 1.6 1 1 0 1 1 1 0 NAD(P)H-binding DUF1192 PF06698.11 ACL96868.1 - 1.9e-19 69.5 3.2 1.9e-19 69.4 3.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) ABC_tran_CTD PF16326.5 ACL96868.1 - 0.0021 18.2 0.6 0.0024 18.1 0.6 1.3 1 0 0 1 1 1 1 ABC transporter C-terminal domain FlxA PF14282.6 ACL96868.1 - 0.0094 15.9 0.1 0.01 15.8 0.1 1.1 1 0 0 1 1 1 1 FlxA-like protein HalX PF08663.10 ACL96868.1 - 0.01 16.1 0.5 0.012 15.9 0.5 1.4 1 0 0 1 1 1 0 HalX domain THOC7 PF05615.13 ACL96868.1 - 0.041 14.2 1.2 0.05 13.9 1.2 1.1 1 0 0 1 1 1 0 Tho complex subunit 7 DUF3618 PF12277.8 ACL96868.1 - 0.044 14.0 1.7 0.044 14.0 1.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) DUF2344 PF10105.9 ACL96868.1 - 0.073 12.9 0.0 0.074 12.9 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) DUF1465 PF07323.12 ACL96869.1 - 7.4e-61 204.5 0.7 8.3e-61 204.3 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1465) COQ9 PF08511.11 ACL96870.1 - 3.7e-20 71.5 0.5 6.4e-20 70.7 0.5 1.4 1 0 0 1 1 1 1 COQ9 Ribosomal_S21 PF01165.20 ACL96871.2 - 1.6e-18 66.2 9.1 1.6e-18 66.2 9.1 1.8 1 1 1 2 2 2 1 Ribosomal protein S21 DUF2188 PF09954.9 ACL96871.2 - 0.57 10.4 4.4 0.71 10.1 3.7 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) ABC2_membrane_3 PF12698.7 ACL96872.1 - 5e-36 124.5 0.0 9e-36 123.7 0.0 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 ACL96872.1 - 1.9e-08 33.9 11.2 2.8e-08 33.4 11.2 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 ACL96872.1 - 4.3e-06 26.3 11.4 4.3e-06 26.3 11.4 2.3 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.27 ACL96873.1 - 3.5e-25 89.1 0.0 5.4e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ACL96873.1 - 1.2e-13 51.6 0.6 1.4e-08 34.9 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 ACL96873.1 - 2.4e-05 24.9 0.0 4.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4162) Homoserine_dh PF00742.19 ACL96873.1 - 0.004 17.1 0.0 0.0054 16.7 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase AAA_23 PF13476.6 ACL96873.1 - 0.0052 17.3 0.0 0.0082 16.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 ACL96873.1 - 0.0059 16.1 0.0 1.9 7.9 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 ACL96873.1 - 0.0085 16.3 0.0 0.023 14.9 0.0 1.8 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 ACL96873.1 - 0.017 14.8 0.3 0.14 11.8 0.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ACL96873.1 - 0.02 15.3 0.1 0.048 14.1 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.6 ACL96873.1 - 0.023 14.4 0.0 0.28 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 ACL96873.1 - 0.18 11.6 0.0 0.43 10.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Abhydrolase_1 PF00561.20 ACL96874.2 - 1.8e-15 57.3 0.0 2.5e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ACL96874.2 - 8.3e-11 41.6 0.4 1.2e-10 41.1 0.1 1.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ACL96874.2 - 2.1e-10 41.6 9.1 3.1e-10 41.0 9.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 ACL96874.2 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_M23 PF01551.22 ACL96875.1 - 1e-25 89.8 0.2 1.6e-25 89.1 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M23 DUF1746 PF08508.10 ACL96875.1 - 0.16 12.3 0.1 0.39 11.1 0.0 1.6 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1746) PNTB PF02233.16 ACL96877.1 - 1.5e-191 637.3 28.5 1.7e-191 637.1 28.5 1.0 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit TPP_enzyme_M PF00205.22 ACL96877.1 - 0.00036 20.3 0.2 0.0019 17.9 0.2 2.1 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Asn_synthase PF00733.21 ACL96877.1 - 0.17 11.5 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase Flavi_NS2A PF01005.19 ACL96877.1 - 0.24 11.5 13.2 0.088 13.0 3.1 2.4 2 0 0 2 2 2 0 Flavivirus non-structural protein NS2A Peptidase_M48_N PF16491.5 ACL96877.1 - 2.7 7.8 6.6 7.6 6.4 6.6 1.7 1 0 0 1 1 1 0 CAAX prenyl protease N-terminal, five membrane helices PNTB_4TM PF12769.7 ACL96878.1 - 2.2e-35 120.9 5.8 2.8e-35 120.6 5.8 1.1 1 0 0 1 1 1 1 4TM region of pyridine nucleotide transhydrogenase, mitoch PspC PF04024.12 ACL96878.1 - 0.0039 17.0 1.0 0.0089 15.8 1.0 1.5 1 0 0 1 1 1 1 PspC domain DUF3392 PF11872.8 ACL96878.1 - 0.0047 17.2 2.7 0.0047 17.2 2.7 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3392) DUF485 PF04341.12 ACL96878.1 - 8.2 6.5 9.3 2.1 8.4 5.5 1.8 1 1 1 2 2 2 0 Protein of unknown function, DUF485 AlaDh_PNT_C PF01262.21 ACL96879.1 - 9.4e-73 244.0 7.9 1.8e-72 243.1 7.9 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 ACL96879.1 - 2.1e-46 157.6 3.4 2.1e-46 157.6 3.4 2.5 2 1 1 3 3 3 1 Alanine dehydrogenase/PNT, N-terminal domain 2-Hacid_dh_C PF02826.19 ACL96879.1 - 7.4e-05 22.2 4.5 0.015 14.7 0.2 3.2 3 1 1 4 4 4 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 ACL96879.1 - 0.0044 17.0 0.8 0.0044 17.0 0.8 2.8 2 1 1 3 3 3 1 Zinc-binding dehydrogenase XdhC_C PF13478.6 ACL96879.1 - 0.32 11.5 3.9 1.1 9.8 0.1 2.5 2 1 0 2 2 2 0 XdhC Rossmann domain COX4_pro_2 PF07835.12 ACL96880.1 - 3.2e-16 59.2 0.2 3.2e-16 59.2 0.2 2.1 2 0 0 2 2 2 1 Bacterial aa3 type cytochrome c oxidase subunit IV DUF2516 PF10724.9 ACL96880.1 - 0.063 13.6 0.8 0.086 13.1 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2516) SLATT_6 PF18169.1 ACL96880.1 - 0.097 12.3 0.3 0.11 12.1 0.3 1.0 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 DUF2207 PF09972.9 ACL96880.1 - 0.2 10.4 1.1 0.22 10.2 1.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MRAP PF15183.6 ACL96880.1 - 0.35 10.8 5.2 0.078 12.9 2.0 1.5 1 1 1 2 2 2 0 Melanocortin-2 receptor accessory protein family Glyco_transf_9 PF01075.17 ACL96881.1 - 1.4e-16 60.5 0.0 2e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 9 (heptosyltransferase) Abhydrolase_6 PF12697.7 ACL96882.1 - 7.1e-19 69.3 6.8 7.1e-19 69.3 6.8 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ACL96882.1 - 3.9e-18 66.0 0.0 2.4e-14 53.6 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ACL96882.1 - 6.7e-11 41.9 0.0 8.8e-11 41.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 ACL96882.1 - 0.0062 16.2 0.0 0.0087 15.7 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 ACL96882.1 - 0.19 11.5 0.1 20 4.9 0.1 2.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PAF-AH_p_II PF03403.13 ACL96882.1 - 0.24 9.9 0.0 0.34 9.4 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II 4HBT PF03061.22 ACL96883.1 - 2.8e-14 53.2 0.0 3.7e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 ACL96883.1 - 0.08 13.1 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) Sigma70_r2 PF04542.14 ACL96884.1 - 2.4e-15 56.1 1.4 4.1e-15 55.3 1.4 1.4 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4_2 PF08281.12 ACL96884.1 - 1e-12 47.5 0.2 1.6e-12 46.8 0.2 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_28 PF13518.6 ACL96884.1 - 0.0085 16.2 0.1 0.021 15.0 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AsnC-type PF13404.6 ACL96884.1 - 0.02 14.7 2.7 0.03 14.2 0.1 2.3 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Sigma70_r4 PF04545.16 ACL96884.1 - 0.041 13.4 0.2 0.041 13.4 0.2 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 RIIa PF02197.17 ACL96884.1 - 0.058 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit MFS_MOT1 PF16983.5 ACL96885.1 - 0.0038 17.6 4.3 0.012 16.0 2.2 2.1 1 1 0 2 2 2 1 Molybdate transporter of MFS superfamily PsbH PF00737.20 ACL96885.1 - 0.43 10.3 5.9 0.3 10.8 3.5 2.1 2 1 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein Phage_holin_3_6 PF07332.11 ACL96885.1 - 0.92 9.6 11.4 0.084 12.9 4.3 2.1 1 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Yip1 PF04893.17 ACL96885.1 - 3.1 7.5 9.3 13 5.4 9.1 1.8 1 1 0 1 1 1 0 Yip1 domain DUF4079 PF13301.6 ACL96885.1 - 3.6 7.7 7.8 1.4 9.1 3.5 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF4079) ABC1 PF03109.16 ACL96886.1 - 4.7e-26 91.3 0.0 7.7e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 ACL96886.1 - 0.0034 17.3 4.9 0.0092 15.9 4.0 2.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Peptidase_M3 PF01432.20 ACL96887.1 - 6.3e-32 111.4 0.1 7.4e-31 107.9 0.1 2.0 1 1 0 1 1 1 1 Peptidase family M3 Peptidase_M3_N PF08439.10 ACL96887.1 - 2.5e-11 43.7 0.5 6.7e-11 42.3 0.1 2.0 2 0 0 2 2 2 1 Oligopeptidase F Peptidase_M78 PF06114.13 ACL96887.1 - 0.085 12.8 0.5 0.64 10.0 0.0 2.3 2 1 0 2 2 2 0 IrrE N-terminal-like domain T2SSF PF00482.23 ACL96887.1 - 0.29 11.1 1.2 0.77 9.7 0.1 2.3 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F DUF4157 PF13699.6 ACL96887.1 - 9.4 6.5 6.8 4.8 7.5 0.2 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4157) YjbR PF04237.13 ACL96888.1 - 2.8e-07 31.0 0.0 3.3e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 YjbR Sigma54_activat PF00158.26 ACL96889.1 - 4.2e-70 234.8 0.0 6.1e-70 234.3 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Response_reg PF00072.24 ACL96889.1 - 3.2e-26 91.7 0.0 6.7e-26 90.7 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Sigma54_activ_2 PF14532.6 ACL96889.1 - 5.7e-20 71.8 0.0 1.5e-19 70.5 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain HTH_8 PF02954.19 ACL96889.1 - 2e-16 59.5 0.1 6.2e-14 51.5 0.1 2.6 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family AAA_5 PF07728.14 ACL96889.1 - 1.1e-05 25.4 0.0 4.1e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) HTH_50 PF18024.1 ACL96889.1 - 4e-05 23.1 0.2 0.00011 21.8 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain AAA PF00004.29 ACL96889.1 - 4.3e-05 23.9 0.1 0.00024 21.6 0.0 2.3 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) HTH_17 PF12728.7 ACL96889.1 - 0.00055 20.1 0.1 0.0035 17.5 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.15 ACL96889.1 - 0.00062 19.8 0.0 0.0017 18.4 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase Mg_chelatase PF01078.21 ACL96889.1 - 0.0055 16.1 0.4 0.72 9.2 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RWP-RK PF02042.15 ACL96889.1 - 0.012 15.6 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 RWP-RK domain HTH_23 PF13384.6 ACL96889.1 - 0.012 15.4 0.2 0.033 14.0 0.2 1.8 1 0 0 1 1 1 0 Homeodomain-like domain OKR_DC_1_N PF03709.15 ACL96889.1 - 0.034 14.4 0.0 0.12 12.6 0.0 1.9 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain TetR_N PF00440.23 ACL96889.1 - 0.041 13.7 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family FleQ PF06490.11 ACL96889.1 - 0.054 13.9 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ HTH_28 PF13518.6 ACL96889.1 - 0.065 13.4 0.1 0.22 11.7 0.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_22 PF13309.6 ACL96889.1 - 0.074 13.1 0.1 0.32 11.1 0.0 2.2 2 0 0 2 2 1 0 HTH domain AAA_16 PF13191.6 ACL96889.1 - 0.099 13.0 0.4 0.32 11.4 0.1 2.2 2 1 0 2 2 1 0 AAA ATPase domain Phage_AlpA PF05930.12 ACL96889.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) CENP-B_N PF04218.13 ACL96889.1 - 0.17 11.6 0.0 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.6 ACL96889.1 - 0.26 11.1 1.1 0.47 10.2 0.2 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain MarR PF01047.22 ACL96891.2 - 0.0014 18.5 0.0 0.026 14.4 0.0 2.7 2 1 0 2 2 2 1 MarR family DUF2312 PF10073.9 ACL96893.1 - 7.1e-33 112.1 6.1 8.2e-33 111.9 6.1 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2312) CdiA_C PF18451.1 ACL96893.1 - 0.014 15.6 2.1 0.47 10.7 0.7 2.0 1 1 1 2 2 2 0 Contact-dependent growth inhibition CdiA C-terminal domain DUF724 PF05266.14 ACL96893.1 - 0.024 14.5 0.2 0.03 14.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) B277 PF17623.2 ACL96893.1 - 0.027 13.5 1.4 0.029 13.5 1.4 1.0 1 0 0 1 1 1 0 Domain of unknown function MtrA PF04208.14 ACL96893.1 - 0.056 13.1 0.5 0.062 12.9 0.5 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A HAD_2 PF13419.6 ACL96894.1 - 1.3e-08 35.1 0.0 1.8e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ACL96894.1 - 5.2e-05 23.6 0.0 8e-05 23.0 0.0 1.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ACL96894.1 - 0.00013 21.9 0.0 0.00025 21.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.7 ACL96894.1 - 0.036 13.9 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Acid Phosphatase DUF2608 PF11019.8 ACL96894.1 - 0.24 10.9 0.0 0.51 9.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) Ribosomal_L36 PF00444.18 ACL96895.1 - 6.1e-18 64.7 3.6 6.8e-18 64.6 3.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L36 zf-TRM13_CCCH PF11722.8 ACL96895.1 - 0.0059 16.3 0.4 0.011 15.5 0.4 1.5 1 0 0 1 1 1 1 CCCH zinc finger in TRM13 protein SLT_2 PF13406.6 ACL96896.1 - 5.9e-96 321.1 0.0 7.1e-96 320.9 0.0 1.1 1 0 0 1 1 1 1 Transglycosylase SLT domain PG_binding_1 PF01471.18 ACL96896.1 - 3.9e-13 49.4 0.0 7.3e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Glucosaminidase PF01832.20 ACL96896.1 - 0.0082 16.6 0.0 0.021 15.3 0.0 1.5 1 1 0 1 1 1 1 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase PG_binding_2 PF08823.11 ACL96896.1 - 0.0094 16.2 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 1 Putative peptidoglycan binding domain DEC-1_N PF04625.13 ACL96896.1 - 0.028 13.5 6.7 0.05 12.6 6.7 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region VCBS PF13517.6 ACL96896.1 - 0.083 13.5 0.1 0.21 12.2 0.1 1.6 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF3558 PF12079.8 ACL96896.1 - 1 9.4 5.2 1.5 8.8 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) Aldose_epim PF01263.20 ACL96897.1 - 5.6e-49 167.1 0.0 6.2e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase HTH_42 PF06224.12 ACL96898.1 - 1.3e-74 251.7 27.7 1.6e-74 251.4 27.7 1.1 1 0 0 1 1 1 1 Winged helix DNA-binding domain Response_reg PF00072.24 ACL96899.2 - 5.8e-25 87.6 0.0 7.8e-25 87.2 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 ACL96899.2 - 1.2e-20 73.3 0.0 2.3e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal FecR PF04773.13 ACL96900.3 - 6e-15 55.6 0.1 1.4e-14 54.5 0.1 1.7 1 0 0 1 1 1 1 FecR protein LysM PF01476.20 ACL96900.3 - 4.1e-07 29.9 0.0 7.5e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 LysM domain PPC PF04151.15 ACL96900.3 - 0.038 15.1 0.2 24 6.1 0.0 3.2 3 0 0 3 3 3 0 Bacterial pre-peptidase C-terminal domain CHASE2 PF05226.11 ACL96901.1 - 4.5e-49 167.4 0.5 9.6e-49 166.4 0.2 1.6 2 0 0 2 2 2 1 CHASE2 domain HATPase_c PF02518.26 ACL96901.1 - 2.4e-16 60.2 0.0 4.1e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 ACL96901.1 - 3.3e-16 59.5 0.1 9.3e-16 58.1 0.1 1.9 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 ACL96901.1 - 0.00013 21.9 0.0 0.00032 20.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 ACL96901.1 - 0.0015 18.7 0.0 0.0027 17.9 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 ACL96901.1 - 0.021 14.8 0.1 0.074 13.1 0.1 1.9 1 0 0 1 1 1 0 PAS domain MttA_Hcf106 PF02416.16 ACL96904.2 - 0.0065 15.8 0.0 0.0077 15.5 0.0 1.2 1 0 0 1 1 1 1 mttA/Hcf106 family UPF0061 PF02696.14 ACL96905.1 - 1.4e-78 264.8 0.0 3.6e-78 263.4 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family DDE_Tnp_1_2 PF13586.6 ACL96906.1 - 1.8e-17 63.5 0.2 2.3e-17 63.2 0.2 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 ACL96906.1 - 4.4e-11 42.8 0.4 5.9e-10 39.2 0.4 1.9 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 ACL96906.1 - 2e-05 24.3 0.0 2.3e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_3 PF13612.6 ACL96906.1 - 4.2e-05 23.6 0.0 5.3e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_5 PF13546.6 ACL96906.1 - 0.007 15.7 0.1 0.0081 15.5 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease BT1 PF03092.16 ACL96906.1 - 0.047 11.9 0.0 0.05 11.8 0.0 1.0 1 0 0 1 1 1 0 BT1 family DUF4096 PF13340.6 ACL96907.1 - 1.4e-25 89.3 3.5 1.9e-25 88.9 3.5 1.2 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) UPF0061 PF02696.14 ACL96908.1 - 9.4e-48 163.1 0.0 1.1e-47 162.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family TonB_dep_Rec PF00593.24 ACL96909.1 - 1.2e-38 134.2 28.6 1.7e-38 133.7 28.6 1.3 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 ACL96909.1 - 4.4e-15 56.2 3.8 5.8e-15 55.8 2.4 2.1 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain DUF4158 PF13700.6 ACL96909.1 - 0.16 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) Peptidase_M28 PF04389.17 ACL96910.2 - 2e-41 141.9 0.0 3e-41 141.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 ACL96910.2 - 5.7e-08 32.7 0.0 8.4e-08 32.2 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 ACL96910.2 - 9.9e-05 21.5 0.0 0.00031 19.9 0.0 1.6 1 1 1 2 2 2 1 M42 glutamyl aminopeptidase Gaa1 PF04114.14 ACL96910.2 - 0.05 12.6 0.0 0.089 11.8 0.0 1.3 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component Syndecan PF01034.20 ACL96910.2 - 2.2 8.3 3.7 2.8 7.9 1.4 2.4 2 0 0 2 2 2 0 Syndecan domain AMP-binding PF00501.28 ACL96911.1 - 9.1e-58 195.8 0.1 1.2e-57 195.4 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF3592 PF12158.8 ACL96911.1 - 0.051 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) Zn_Tnp_IS1595 PF12760.7 ACL96912.1 - 0.0047 16.9 0.7 0.0089 16.0 0.7 1.5 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Ribosomal_L12_N PF16320.5 ACL96912.1 - 0.21 11.3 3.2 0.38 10.5 3.2 1.4 1 0 0 1 1 1 0 Ribosomal protein L7/L12 dimerisation domain Lar_restr_allev PF14354.6 ACL96912.1 - 3.3 8.2 5.8 8.7 6.8 5.8 1.6 1 1 0 1 1 1 0 Restriction alleviation protein Lar ChitinaseA_N PF08329.10 ACL96913.2 - 0.1 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Chitinase A, N-terminal domain MethyTransf_Reg PF10119.9 ACL96914.2 - 1.7e-28 99.2 0.4 3.8e-28 98.0 0.4 1.7 1 0 0 1 1 1 1 Predicted methyltransferase regulatory domain Methyltransf_25 PF13649.6 ACL96914.2 - 5.7e-08 33.4 0.0 2.7e-07 31.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ACL96914.2 - 3.1e-06 27.9 0.0 5.8e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ACL96914.2 - 3.3e-05 24.5 0.0 8.4e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ACL96914.2 - 0.00037 20.4 0.0 0.0016 18.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain CheR PF01739.18 ACL96914.2 - 0.22 11.0 0.0 0.35 10.3 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain TetR_N PF00440.23 ACL96918.2 - 1.2e-14 53.8 0.3 3.7e-14 52.2 0.3 1.9 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family Metallophos_2 PF12850.7 ACL96919.1 - 3.3e-13 50.2 0.4 1.3e-12 48.3 0.4 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 ACL96919.1 - 1.1e-11 45.6 6.4 3.6e-11 44.0 6.4 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_trans_1_4 PF13692.6 ACL96920.1 - 1.3e-18 67.8 0.0 2.4e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 ACL96920.1 - 1e-16 61.0 0.0 1.6e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ACL96920.1 - 3.3e-16 59.7 2.0 5.2e-16 59.1 0.1 2.2 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 ACL96920.1 - 2.9e-07 31.1 4.1 1.1e-06 29.2 0.2 3.0 2 2 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 ACL96920.1 - 0.0031 17.9 0.0 0.014 15.7 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Abhydrolase_3 PF07859.13 ACL96921.1 - 6e-22 78.5 0.3 9.3e-17 61.6 0.5 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ACL96921.1 - 1.6e-09 37.5 0.0 0.00064 19.3 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 ACL96921.1 - 1.2e-07 31.1 0.0 2.8e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.18 ACL96921.1 - 3.2e-05 23.6 0.0 0.00083 19.0 0.0 2.3 3 0 0 3 3 3 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 ACL96921.1 - 0.00017 20.9 0.0 0.26 10.5 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Esterase_phd PF10503.9 ACL96921.1 - 0.00097 18.7 0.7 0.0035 16.9 0.7 1.8 1 1 0 1 1 1 1 Esterase PHB depolymerase AXE1 PF05448.12 ACL96921.1 - 0.083 11.6 0.2 0.24 10.0 0.1 1.7 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) VKG_Carbox PF05090.14 ACL96922.3 - 1.2e-08 34.2 2.2 1.8e-08 33.6 2.2 1.1 1 0 0 1 1 1 1 Vitamin K-dependent gamma-carboxylase LMF1 PF06762.14 ACL96922.3 - 1.3 8.0 6.5 1.5 7.8 6.5 1.1 1 0 0 1 1 1 0 Lipase maturation factor MCPsignal PF00015.21 ACL96924.1 - 8.4e-56 188.5 37.6 3.4e-52 176.7 20.7 3.7 2 1 1 3 3 3 3 Methyl-accepting chemotaxis protein (MCP) signalling domain PAS_3 PF08447.12 ACL96924.1 - 3.1e-32 110.7 0.0 6.9e-17 61.5 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 ACL96924.1 - 1e-27 96.5 0.0 2.7e-12 46.9 0.0 3.6 2 1 0 3 3 3 2 PAS fold PAS_9 PF13426.7 ACL96924.1 - 6e-26 90.7 0.0 4e-12 46.3 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 ACL96924.1 - 3.7e-17 62.4 0.0 4.7e-07 29.8 0.0 3.0 2 1 1 3 3 3 2 PAS fold sCache_3_3 PF17202.4 ACL96924.1 - 0.0017 18.8 0.0 3.5 8.1 0.0 3.0 2 0 0 2 2 2 2 Single cache domain 3 BLOC1_2 PF10046.9 ACL96924.1 - 0.012 15.8 13.2 3.2 8.1 0.2 6.0 4 2 2 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 ACL96924.1 - 0.031 14.3 13.6 0.28 11.2 2.6 4.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) KxDL PF10241.9 ACL96924.1 - 0.052 13.8 0.6 7.7 6.9 0.0 3.3 2 1 1 3 3 3 0 Uncharacterized conserved protein DUF948 PF06103.11 ACL96924.1 - 0.078 13.2 27.5 6.7 7.1 0.6 6.3 5 2 1 7 7 7 0 Bacterial protein of unknown function (DUF948) Syntaxin-6_N PF09177.11 ACL96924.1 - 1.1 9.9 10.0 10 6.7 0.3 4.1 4 2 2 6 6 6 0 Syntaxin 6, N-terminal HAMP PF00672.25 ACL96924.1 - 1.6 9.2 10.6 2.1 8.8 0.1 4.7 4 1 1 5 5 5 0 HAMP domain NPV_P10 PF05531.12 ACL96924.1 - 8.7 6.9 22.1 1.2 9.7 0.6 5.7 4 1 2 6 6 6 0 Nucleopolyhedrovirus P10 protein PGPGW PF09656.10 ACL96926.1 - 0.0039 16.7 2.2 0.0086 15.6 2.2 1.6 1 0 0 1 1 1 1 Putative transmembrane protein (PGPGW) DUF1145 PF06611.12 ACL96926.1 - 0.38 10.7 4.3 0.71 9.9 4.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1145) Aminotran_5 PF00266.19 ACL96927.1 - 1.4e-09 37.4 0.0 2e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V GDC-P PF02347.16 ACL96927.1 - 3.9e-08 32.6 0.0 2.8e-07 29.7 0.0 1.9 1 1 0 1 1 1 1 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 ACL96927.1 - 0.0025 17.2 0.3 0.0039 16.5 0.3 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.16 ACL96928.1 - 1.2e-118 396.6 0.0 1.4e-118 396.4 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage system P-protein Aminotran_5 PF00266.19 ACL96928.1 - 2.5e-09 36.6 0.8 3.2e-09 36.2 0.8 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 ACL96928.1 - 2.3e-07 29.7 2.6 2.3e-07 29.7 2.6 1.6 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Ntox22 PF15527.6 ACL96928.1 - 4.4 7.4 7.3 1e+02 3.0 7.3 2.3 1 1 0 1 1 1 0 Bacterial toxin 22 GCV_H PF01597.19 ACL96929.1 - 4e-41 139.7 0.1 4.8e-41 139.5 0.1 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 ACL96929.1 - 0.00018 21.3 2.4 0.00033 20.4 1.4 1.8 1 1 1 2 2 2 1 Biotin-requiring enzyme RnfC_N PF13375.6 ACL96929.1 - 0.056 13.4 0.7 0.083 12.9 0.6 1.4 1 1 0 1 1 1 0 RnfC Barrel sandwich hybrid domain GCV_T PF01571.21 ACL96930.1 - 6.9e-88 294.3 0.0 8.3e-88 294.1 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 ACL96930.1 - 5.2e-17 61.5 0.3 1.2e-16 60.3 0.3 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DUF3659 PF12396.8 ACL96930.1 - 0.0006 19.7 0.7 0.0049 16.8 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3659) SoxG PF04268.12 ACL96930.1 - 0.003 17.7 0.0 0.0095 16.1 0.0 1.8 2 0 0 2 2 2 1 Sarcosine oxidase, gamma subunit family POPLD PF08170.12 ACL96930.1 - 0.023 15.0 0.0 0.041 14.2 0.0 1.4 1 0 0 1 1 1 0 POPLD (NUC188) domain ORF6N PF10543.9 ACL96931.1 - 1.3e-22 79.7 0.0 2.5e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 ORF6N domain DUF4953 PF16313.5 ACL96932.1 - 1.5e-66 224.9 0.0 2.6e-66 224.0 0.0 1.4 1 0 0 1 1 1 1 Met-zincin DUF5117 PF17148.4 ACL96932.1 - 1.5e-27 96.7 0.0 2.2e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5117) Peptidase_M10 PF00413.24 ACL96932.1 - 0.007 16.2 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Matrixin Reprolysin_5 PF13688.6 ACL96932.1 - 0.0089 16.2 0.0 0.017 15.3 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 ACL96932.1 - 0.043 14.3 0.0 0.098 13.2 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 ACL96932.1 - 0.088 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 ACL96932.1 - 0.1 11.5 0.1 0.18 10.7 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 MCPsignal PF00015.21 ACL96933.1 - 1e-43 149.1 25.7 3.2e-43 147.5 14.3 2.9 3 0 0 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain HAMP PF00672.25 ACL96933.1 - 3.4e-11 43.3 11.0 4.9e-08 33.2 0.1 4.2 4 0 0 4 4 4 2 HAMP domain Laminin_II PF06009.12 ACL96933.1 - 0.0072 16.3 4.5 0.27 11.3 0.2 2.8 2 1 0 2 2 2 2 Laminin Domain II Sec8_exocyst PF04048.14 ACL96933.1 - 0.11 12.4 3.2 3.7 7.4 0.0 3.0 3 1 1 4 4 4 0 Sec8 exocyst complex component specific domain BLOC1_2 PF10046.9 ACL96933.1 - 0.13 12.6 2.7 11 6.4 0.0 3.6 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HAUS-augmin3 PF14932.6 ACL96933.1 - 0.21 11.1 3.3 0.55 9.8 0.9 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 ALIX_LYPXL_bnd PF13949.6 ACL96933.1 - 0.46 9.7 3.4 0.51 9.6 0.3 2.2 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV I_LWEQ PF01608.17 ACL96933.1 - 1 9.6 20.3 0.52 10.5 2.7 3.2 1 1 1 3 3 3 0 I/LWEQ domain DUF948 PF06103.11 ACL96933.1 - 4.1 7.7 21.7 0.67 10.3 1.8 4.3 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) tRNA-synt_1d PF00750.19 ACL96934.1 - 3.7e-74 249.8 0.0 3.9e-49 167.5 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.15 ACL96934.1 - 2.6e-27 95.3 0.5 4.8e-27 94.5 0.5 1.5 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 ACL96934.1 - 8.5e-18 64.7 0.0 2.8e-17 63.1 0.0 2.0 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain LYTB PF02401.18 ACL96936.1 - 7.4e-89 297.5 0.0 8.6e-89 297.3 0.0 1.0 1 0 0 1 1 1 1 LytB protein DUF460 PF04312.13 ACL96936.1 - 0.021 14.5 0.1 0.25 11.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF460) Fic PF02661.18 ACL96938.1 - 2.4e-11 44.4 0.0 3.5e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Fic/DOC family MazE_antitoxin PF04014.18 ACL96939.1 - 0.00012 21.9 0.0 0.00016 21.5 0.0 1.2 1 0 0 1 1 1 1 Antidote-toxin recognition MazE, bacterial antitoxin TOBE_3 PF12857.7 ACL96939.1 - 0.051 13.5 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 TOBE-like domain APH PF01636.23 ACL96940.1 - 1.3e-31 110.4 0.1 1.7e-31 110.0 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ACL96940.1 - 0.0049 16.5 0.4 0.0074 15.9 0.4 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RNase_H PF00075.24 ACL96941.1 - 8.3e-50 168.7 0.0 9.3e-50 168.5 0.0 1.0 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 ACL96941.1 - 0.1 12.4 0.0 0.4 10.5 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase-like Rhodanese PF00581.20 ACL96942.2 - 4.7e-08 33.5 0.0 7.2e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Phosphonate-bd PF12974.7 ACL96942.2 - 0.05 13.2 0.1 0.061 12.9 0.1 1.1 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein HTH_18 PF12833.7 ACL96943.2 - 6.2e-19 68.0 3.0 1.1e-18 67.2 3.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain DJ-1_PfpI PF01965.24 ACL96943.2 - 9.2e-15 54.8 0.0 1.2e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family HTH_AraC PF00165.23 ACL96943.2 - 2.9e-13 49.5 0.0 6.1e-06 26.2 0.0 2.2 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family TetR_N PF00440.23 ACL96943.2 - 3.3e-05 23.6 0.2 0.052 13.3 0.0 2.6 2 0 0 2 2 2 2 Bacterial regulatory proteins, tetR family DprA_WH PF17782.1 ACL96943.2 - 0.068 13.3 0.2 0.17 12.0 0.2 1.6 1 0 0 1 1 1 0 DprA winged helix domain MerR PF00376.23 ACL96943.2 - 0.11 12.3 0.1 24 4.8 0.0 3.0 2 0 0 2 2 2 0 MerR family regulatory protein HTH_AsnC-type PF13404.6 ACL96943.2 - 0.13 12.1 2.0 17 5.4 0.1 3.1 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain HTH_5 PF01022.20 ACL96943.2 - 0.15 11.9 0.0 0.45 10.4 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_24 PF13412.6 ACL96943.2 - 0.21 11.2 0.0 7.1 6.3 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HxlR PF01638.17 ACL96944.1 - 1.3e-25 89.0 0.1 1.7e-25 88.7 0.1 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_34 PF13601.6 ACL96944.1 - 0.0022 18.1 0.0 0.0031 17.7 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain NAD_binding_10 PF13460.6 ACL96945.1 - 4.9e-23 82.0 4.5 8.3e-23 81.2 4.5 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ACL96945.1 - 2.5e-20 73.0 0.0 7.1e-20 71.6 0.1 1.6 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 ACL96945.1 - 0.00027 20.5 0.5 0.001 18.6 0.1 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ACL96945.1 - 0.0009 18.3 0.0 0.002 17.2 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ACL96945.1 - 0.00094 18.4 1.8 0.17 11.0 0.1 2.7 1 1 1 2 2 2 2 RmlD substrate binding domain NAD_binding_4 PF07993.12 ACL96945.1 - 0.0019 17.4 0.0 0.0029 16.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein DapB_N PF01113.20 ACL96945.1 - 0.0028 17.8 0.0 0.0053 16.9 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 ACL96945.1 - 0.0062 16.5 0.2 0.0062 16.5 0.2 1.8 2 1 0 2 2 2 1 KR domain GFO_IDH_MocA PF01408.22 ACL96945.1 - 0.045 14.6 0.4 0.13 13.1 0.1 1.8 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.18 ACL96945.1 - 0.11 12.7 0.4 0.23 11.7 0.1 1.7 2 0 0 2 2 2 0 TrkA-N domain Semialdhyde_dh PF01118.24 ACL96945.1 - 0.12 12.8 0.3 0.71 10.3 0.1 2.2 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 ACL96945.1 - 0.14 11.2 0.1 6.6 5.8 0.0 2.3 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein DUF3842 PF12953.7 ACL96945.1 - 0.23 11.9 2.6 2.7 8.4 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3842) Resolvase PF00239.21 ACL96946.2 - 9.7e-15 54.9 0.0 1.1e-14 54.8 0.0 1.0 1 0 0 1 1 1 1 Resolvase, N terminal domain ABC2_membrane PF01061.24 ACL96947.1 - 5.3e-33 114.2 24.3 5.3e-33 114.2 24.3 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 ACL96947.1 - 5.2e-07 29.1 25.4 5.2e-07 29.1 25.4 1.8 1 1 1 2 2 2 1 ABC-2 family transporter protein ABC_tran PF00005.27 ACL96948.1 - 2.3e-33 115.6 0.0 5.1e-33 114.5 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 ACL96948.1 - 2.3e-13 50.6 0.3 1.8e-07 31.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 ACL96948.1 - 6.1e-05 23.7 0.0 0.00017 22.2 0.0 1.7 2 0 0 2 2 1 1 Domain of unknown function (DUF4162) NB-ARC PF00931.22 ACL96948.1 - 8.1e-05 21.9 0.6 0.027 13.6 0.1 2.1 2 0 0 2 2 2 2 NB-ARC domain AAA_23 PF13476.6 ACL96948.1 - 0.0001 22.9 0.1 0.00024 21.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 ACL96948.1 - 0.00012 21.7 0.0 0.011 15.2 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 ACL96948.1 - 0.00016 22.1 0.1 0.0023 18.3 0.1 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 ACL96948.1 - 0.00031 20.5 0.2 0.35 10.6 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 ACL96948.1 - 0.00036 20.3 0.0 0.27 10.9 0.0 2.2 1 1 1 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 ACL96948.1 - 0.0026 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 ACL96948.1 - 0.0036 17.7 0.7 0.023 15.1 0.7 2.3 1 1 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 ACL96948.1 - 0.012 15.6 0.0 0.038 14.0 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 ACL96948.1 - 0.018 15.0 0.1 0.04 13.8 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase ATPase PF06745.13 ACL96948.1 - 0.026 13.9 0.5 0.76 9.1 0.1 2.3 2 0 0 2 2 2 0 KaiC T2SSE PF00437.20 ACL96948.1 - 0.032 13.3 0.0 0.072 12.1 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein Hydrolase PF00702.26 ACL96948.1 - 0.04 14.2 0.0 0.13 12.5 0.0 1.8 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Mg_chelatase PF01078.21 ACL96948.1 - 0.09 12.1 0.3 1.4 8.2 0.1 2.1 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI SbcCD_C PF13558.6 ACL96948.1 - 0.14 12.4 0.0 0.39 11.0 0.0 1.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit cobW PF02492.19 ACL96948.1 - 0.14 11.7 0.1 0.38 10.3 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NfeD PF01957.18 ACL96949.1 - 1.1e-17 64.2 0.9 1.2e-17 64.0 0.0 1.5 2 0 0 2 2 2 1 NfeD-like C-terminal, partner-binding Band_7 PF01145.25 ACL96950.1 - 3.7e-31 108.5 19.1 2.3e-29 102.7 19.1 2.2 1 1 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 ACL96950.1 - 2.8e-13 49.7 0.5 6.6e-13 48.5 0.5 1.7 1 0 0 1 1 1 1 C-terminal region of band_7 Band_7_1 PF13421.6 ACL96950.1 - 0.066 12.9 0.2 0.11 12.2 0.2 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family FeoB_N PF02421.18 ACL96950.1 - 0.2 11.2 1.5 0.33 10.5 1.5 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B DUF2385 PF09539.10 ACL96951.1 - 1.5e-26 92.7 1.3 2e-26 92.3 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2385) SPOR PF05036.13 ACL96952.2 - 0.018 15.4 0.2 0.025 14.9 0.2 1.2 1 0 0 1 1 1 0 Sporulation related domain DUF2188 PF09954.9 ACL96952.2 - 0.068 13.3 0.0 0.085 13.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) DUF2275 PF10039.9 ACL96953.1 - 2.1 8.4 5.6 0.28 11.3 0.9 1.8 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2275) DUF2627 PF11118.8 ACL96953.1 - 6.8 7.3 6.9 29 5.3 2.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2627) DUF2644 PF10841.8 ACL96953.1 - 7.5 6.8 7.1 1.2 9.4 1.6 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2644) NMO PF03060.15 ACL96954.1 - 1.4e-67 228.4 7.8 8.3e-66 222.6 7.8 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 ACL96954.1 - 1.2e-09 37.7 1.0 1.8e-07 30.5 1.0 2.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 ACL96954.1 - 3.9e-05 23.1 2.7 7.2e-05 22.2 2.7 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG FMN_dh PF01070.18 ACL96954.1 - 4.7e-05 22.6 8.7 4.7e-05 22.6 8.7 2.1 2 1 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 ACL96954.1 - 0.004 16.6 0.9 0.0088 15.5 0.9 1.5 1 1 0 1 1 1 1 Histidine biosynthesis protein DUF561 PF04481.12 ACL96954.1 - 0.12 11.5 0.1 0.2 10.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF561) TMP-TENI PF02581.17 ACL96954.1 - 0.15 11.4 1.7 0.49 9.7 1.7 1.9 1 1 0 1 1 1 0 Thiamine monophosphate synthase adh_short_C2 PF13561.6 ACL96956.1 - 3.5e-60 203.5 6.4 4.3e-60 203.2 6.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ACL96956.1 - 1.4e-46 158.4 6.0 1.8e-46 158.1 6.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ACL96956.1 - 9.3e-16 58.3 1.6 1.3e-15 57.8 1.6 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ACL96956.1 - 0.0027 17.2 1.0 0.027 13.9 1.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 ACL96956.1 - 0.01 16.1 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Glutaredoxin PF00462.24 ACL96956.1 - 0.11 12.7 0.1 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 Glutaredoxin Peptidase_M50 PF02163.22 ACL96957.2 - 2.5e-08 33.5 3.8 3e-05 23.4 1.1 2.3 2 0 0 2 2 2 2 Peptidase family M50 NUDIX PF00293.28 ACL96958.1 - 9.7e-23 80.6 0.7 1.1e-22 80.5 0.7 1.0 1 0 0 1 1 1 1 NUDIX domain Patatin PF01734.22 ACL96959.1 - 3.6e-19 69.7 1.5 4.8e-18 66.1 1.5 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase adh_short PF00106.25 ACL96960.1 - 6.5e-58 195.4 3.5 8e-58 195.1 3.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ACL96960.1 - 2.8e-55 187.4 5.3 5.6e-55 186.4 5.3 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ACL96960.1 - 7.5e-11 42.3 1.0 1.2e-10 41.6 0.8 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ACL96960.1 - 0.053 13.0 0.3 0.1 12.1 0.2 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family MR_MLE_C PF13378.6 ACL96960.1 - 0.18 11.4 3.1 0.35 10.4 3.0 1.7 1 1 0 1 1 1 0 Enolase C-terminal domain-like H2O2_YaaD PF03883.14 ACL96961.1 - 1.6e-85 286.3 0.0 1.8e-85 286.2 0.0 1.0 1 0 0 1 1 1 1 Peroxide stress protein YaaA PLA2_B PF01735.18 ACL96961.1 - 0.064 11.6 0.0 0.093 11.1 0.0 1.2 1 0 0 1 1 1 0 Lysophospholipase catalytic domain Urate_ox_N PF06181.11 ACL96962.1 - 0.051 12.9 2.7 0.074 12.4 2.7 1.1 1 0 0 1 1 1 0 Urate oxidase N-terminal DpnD-PcfM PF14207.6 ACL96962.1 - 0.15 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 DpnD/PcfM-like protein Trep_Strep PF09605.10 ACL96962.1 - 3.8 7.4 13.2 2.1 8.3 4.5 2.6 1 1 1 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) HTH_34 PF13601.6 ACL96963.1 - 1.2e-20 73.5 0.0 1.3e-20 73.3 0.0 1.0 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_20 PF12840.7 ACL96963.1 - 4.4e-07 29.9 0.3 7.8e-07 29.1 0.0 1.4 2 0 0 2 2 1 1 Helix-turn-helix domain MarR_2 PF12802.7 ACL96963.1 - 3e-05 23.8 0.0 3.8e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_5 PF01022.20 ACL96963.1 - 3.5e-05 23.6 1.1 0.00012 21.8 0.1 2.2 2 1 0 2 2 2 1 Bacterial regulatory protein, arsR family HTH_27 PF13463.6 ACL96963.1 - 0.00021 21.7 0.0 0.00028 21.3 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR PF01047.22 ACL96963.1 - 0.00021 21.1 0.0 0.00029 20.7 0.0 1.2 1 0 0 1 1 1 1 MarR family Fe_dep_repress PF01325.19 ACL96963.1 - 0.00036 20.7 0.1 0.00049 20.2 0.1 1.2 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_24 PF13412.6 ACL96963.1 - 0.00098 18.6 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Rrf2 PF02082.20 ACL96963.1 - 0.0012 19.2 0.0 0.0018 18.6 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator HTH_11 PF08279.12 ACL96963.1 - 0.0014 18.5 0.0 0.0048 16.8 0.0 1.8 2 0 0 2 2 2 1 HTH domain PadR PF03551.14 ACL96963.1 - 0.011 15.7 0.0 0.014 15.4 0.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family HxlR PF01638.17 ACL96963.1 - 0.02 14.7 0.0 0.023 14.5 0.0 1.1 1 0 0 1 1 1 0 HxlR-like helix-turn-helix TrmB PF01978.19 ACL96963.1 - 0.044 13.7 0.1 0.06 13.2 0.1 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB RNA_pol_Rpc34 PF05158.12 ACL96963.1 - 0.046 13.1 0.0 0.055 12.9 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit HTH_1 PF00126.27 ACL96963.1 - 0.066 13.2 0.0 0.093 12.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family DUF2513 PF10711.9 ACL96963.1 - 0.11 12.9 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 Hypothetical protein (DUF2513) FAD-oxidase_C PF02913.19 ACL96965.1 - 4.2e-57 193.6 0.2 5.8e-57 193.2 0.2 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 ACL96965.1 - 1.9e-32 111.9 2.8 3.5e-32 111.0 2.8 1.5 1 0 0 1 1 1 1 FAD binding domain TPR_14 PF13428.6 ACL96965.1 - 3 8.9 6.1 4 8.5 0.7 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Sua5_yciO_yrdC PF01300.18 ACL96966.3 - 7.5e-51 172.2 0.0 9.6e-51 171.8 0.0 1.1 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 ACL96966.3 - 6.5e-22 78.5 0.0 1.5e-21 77.3 0.0 1.6 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding YceI PF04264.13 ACL96967.1 - 1.2e-27 97.3 0.9 1.6e-27 96.8 0.9 1.1 1 0 0 1 1 1 1 YceI-like domain Ni_hydr_CYTB PF01292.20 ACL96967.1 - 4.2e-24 85.1 10.3 4.4e-24 85.1 8.8 1.7 2 0 0 2 2 2 1 Prokaryotic cytochrome b561 SARG PF15385.6 ACL96967.1 - 0.06 12.6 0.0 0.083 12.1 0.0 1.1 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein Form-deh_trans PF09163.11 ACL96967.1 - 10 6.0 9.7 0.99 9.2 2.0 2.7 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane YceI PF04264.13 ACL96968.1 - 3.5e-40 137.9 1.1 4.1e-40 137.7 1.1 1.1 1 0 0 1 1 1 1 YceI-like domain Acyl-CoA_dh_1 PF00441.24 ACL96969.1 - 6.8e-24 84.8 4.1 1.8e-23 83.4 4.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_C PF12806.7 ACL96969.1 - 1.4e-20 73.7 9.7 1.4e-20 73.7 9.7 2.1 2 0 0 2 2 2 1 Acetyl-CoA dehydrogenase C-terminal like Acyl-CoA_dh_M PF02770.19 ACL96969.1 - 2.2e-16 59.8 0.0 4.2e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ACL96969.1 - 4.4e-13 49.9 0.3 4.4e-13 49.9 0.3 2.1 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ACL96969.1 - 3.1e-05 24.3 5.5 3.1e-05 24.3 5.5 2.7 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain AcylCoA_DH_N PF12418.8 ACL96969.1 - 0.0066 16.5 0.7 0.021 14.9 0.1 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase N terminal Redoxin PF08534.10 ACL96970.1 - 1.2e-36 125.6 0.1 1.4e-36 125.4 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 ACL96970.1 - 2.4e-13 50.1 0.0 2.8e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF179 PF02622.15 ACL96971.1 - 3.8e-44 150.5 0.0 4.4e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 EAL PF00563.20 ACL96972.1 - 1.5e-69 234.1 0.0 4.5e-69 232.6 0.0 1.7 2 0 0 2 2 2 1 EAL domain GGDEF PF00990.21 ACL96972.1 - 9.1e-18 64.5 0.0 1.9e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Acetyltransf_3 PF13302.7 ACL96973.1 - 1e-22 81.3 0.0 1.2e-22 81.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ACL96973.1 - 2.3e-09 37.5 0.1 3.2e-09 37.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 ACL96973.1 - 5.3e-07 29.9 0.0 5.8e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PsaL PF02605.15 ACL96973.1 - 0.025 14.2 1.5 3.6 7.2 0.1 2.2 1 1 1 2 2 2 0 Photosystem I reaction centre subunit XI Acetyltransf_8 PF13523.6 ACL96973.1 - 0.038 13.7 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ANAPC3 PF12895.7 ACL96973.1 - 0.053 13.7 0.1 0.98 9.7 0.2 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Peptidase_M16_C PF05193.21 ACL96974.1 - 4.1e-35 121.4 0.0 7e-34 117.4 0.0 2.3 2 1 1 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 ACL96974.1 - 1e-31 109.9 0.0 1.9e-31 109.0 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Thr_synth_N PF14821.6 ACL96975.1 - 3.5e-27 94.4 0.0 1.1e-26 92.8 0.0 1.9 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 ACL96975.1 - 3.9e-18 65.9 5.7 8.6e-17 61.5 5.7 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Abhydrolase_9_N PF15420.6 ACL96975.1 - 0.034 14.1 0.3 0.073 13.1 0.3 1.5 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus SURF1 PF02104.15 ACL96976.1 - 1.5e-18 67.7 0.0 2.6e-18 66.9 0.0 1.4 1 1 0 1 1 1 1 SURF1 family DUF983 PF06170.12 ACL96977.1 - 1.7e-29 102.0 2.3 1.7e-29 102.0 2.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF983) DUF2157 PF09925.9 ACL96977.1 - 0.021 14.6 2.5 0.026 14.3 2.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF35_N PF12172.8 ACL96977.1 - 0.051 13.5 2.6 3 7.8 0.5 2.4 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF2207 PF09972.9 ACL96977.1 - 0.073 11.8 1.1 0.082 11.7 1.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Tmemb_55A PF09788.9 ACL96977.1 - 0.083 12.0 0.4 0.096 11.7 0.4 1.3 1 1 0 1 1 1 0 Transmembrane protein 55A Rubredoxin_2 PF18073.1 ACL96977.1 - 0.15 11.8 3.8 4.7 7.0 0.2 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain ADK_lid PF05191.14 ACL96977.1 - 0.21 11.6 0.8 0.4 10.7 0.8 1.5 1 1 0 1 1 1 0 Adenylate kinase, active site lid zinc_ribbon_2 PF13240.6 ACL96977.1 - 0.26 11.0 5.9 4.9 7.0 1.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-LITAF-like PF10601.9 ACL96977.1 - 8.6 6.7 8.8 9.5 6.6 1.1 2.9 1 1 2 3 3 3 0 LITAF-like zinc ribbon domain COX3 PF00510.18 ACL96978.1 - 1.7e-77 260.8 24.0 2.3e-77 260.3 24.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III CtaG_Cox11 PF04442.14 ACL96979.3 - 1.8e-52 177.4 0.1 2.4e-52 176.9 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 SNARE PF05739.19 ACL96980.1 - 0.021 14.8 0.1 0.026 14.5 0.1 1.1 1 0 0 1 1 1 0 SNARE domain CD225 PF04505.12 ACL96980.1 - 0.08 13.1 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Interferon-induced transmembrane protein DUF3357 PF11837.8 ACL96980.1 - 0.1 13.1 0.2 0.11 12.9 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Protocadherin PF08374.11 ACL96980.1 - 0.16 11.9 0.1 0.16 11.9 0.1 1.0 1 0 0 1 1 1 0 Protocadherin UbiA PF01040.18 ACL96981.1 - 1.6e-57 194.7 27.2 1.6e-57 194.7 27.2 1.9 1 1 1 2 2 2 1 UbiA prenyltransferase family COX1 PF00115.20 ACL96982.1 - 1.3e-154 515.3 77.6 1.6e-154 514.9 77.6 1.1 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I COX2 PF00116.20 ACL96983.2 - 6.6e-46 155.1 0.0 1e-45 154.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain COX2_TM PF02790.15 ACL96983.2 - 1.6e-24 85.9 5.0 2.6e-24 85.1 5.0 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, transmembrane domain STE3 PF02076.15 ACL96983.2 - 0.0058 15.9 1.9 0.0083 15.4 1.9 1.1 1 0 0 1 1 1 1 Pheromone A receptor YlaC PF10777.9 ACL96983.2 - 0.026 14.4 0.3 0.039 13.8 0.3 1.3 1 0 0 1 1 1 0 Inner membrane protein YlaC TctB PF07331.11 ACL96983.2 - 0.034 14.4 2.3 0.066 13.5 2.3 1.4 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF1461 PF07314.11 ACL96983.2 - 0.081 12.8 5.1 0.14 12.0 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) TraS PF10624.9 ACL96983.2 - 0.23 11.4 2.9 0.42 10.5 2.9 1.4 1 0 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS PspB PF06667.12 ACL96983.2 - 0.37 10.9 5.5 6.3 6.9 0.7 2.3 2 0 0 2 2 2 0 Phage shock protein B DHHC PF01529.20 ACL96983.2 - 1 9.5 2.8 1.8 8.7 2.8 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase Phage_holin_3_6 PF07332.11 ACL96983.2 - 2.1 8.4 5.6 0.67 10.0 2.0 2.0 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III PadR PF03551.14 ACL96984.1 - 1.6e-20 72.8 0.1 2e-20 72.5 0.1 1.1 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family TrmB PF01978.19 ACL96984.1 - 0.00066 19.5 0.1 0.0014 18.5 0.1 1.6 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_34 PF13601.6 ACL96984.1 - 0.0011 19.1 0.0 0.0015 18.7 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain DUF1495 PF07381.11 ACL96984.1 - 0.0071 16.2 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 Winged helix DNA-binding domain (DUF1495) HxlR PF01638.17 ACL96984.1 - 0.015 15.1 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 HxlR-like helix-turn-helix PaaX PF07848.12 ACL96984.1 - 0.076 13.2 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 PaaX-like protein DUF505 PF04458.12 ACL96984.1 - 0.13 10.6 0.0 0.15 10.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF505) DUF2250 PF10007.9 ACL96984.1 - 0.2 11.8 0.2 5.3 7.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) DUF1700 PF08006.11 ACL96985.1 - 7e-26 90.9 0.0 1.1e-25 90.3 0.0 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1700) DUF1676 PF07898.13 ACL96985.1 - 0.041 13.9 0.1 0.065 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) TMEM191C PF15194.6 ACL96985.1 - 0.1 12.8 0.6 0.19 11.9 0.6 1.4 1 0 0 1 1 1 0 TMEM191C family DUF4234 PF14018.6 ACL96985.1 - 5.7 7.2 6.6 2.7 8.2 0.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) DUF2807 PF10988.8 ACL96986.1 - 5.6e-28 98.0 2.6 5.6e-28 98.0 2.6 1.9 2 0 0 2 2 2 1 Putative auto-transporter adhesin, head GIN domain FlgD_ig PF13860.6 ACL96986.1 - 0.07 13.0 0.7 0.42 10.5 0.0 2.4 2 1 0 2 2 2 0 FlgD Ig-like domain PmbA_TldD PF01523.16 ACL96987.2 - 7.5e-66 222.8 0.5 9.5e-66 222.5 0.5 1.1 1 0 0 1 1 1 1 Putative modulator of DNA gyrase Acetyltransf_1 PF00583.25 ACL96988.1 - 9.8e-09 35.5 0.0 1.3e-08 35.0 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ACL96988.1 - 7.3e-07 29.2 0.0 1.9e-06 27.8 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ACL96988.1 - 0.00033 20.7 0.0 0.00058 19.9 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.7 ACL96988.1 - 0.0018 18.7 0.0 0.0035 17.7 0.0 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ACL96988.1 - 0.0059 16.7 0.0 0.0086 16.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PTR2 PF00854.21 ACL96989.1 - 1.9e-53 181.8 24.6 8.3e-38 130.2 8.9 3.2 2 2 1 3 3 3 2 POT family MFS_1 PF07690.16 ACL96989.1 - 4.6e-09 35.7 55.0 9.4e-06 24.8 15.9 3.3 3 0 0 3 3 3 3 Major Facilitator Superfamily SID-1_RNA_chan PF13965.6 ACL96989.1 - 0.22 9.9 2.2 0.12 10.7 0.2 1.4 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 PetL PF05115.14 ACL96991.1 - 0.057 13.4 2.1 0.089 12.8 2.1 1.4 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit VI (PetL) GCS2 PF04107.13 ACL96992.3 - 2.9e-111 371.5 0.0 3.4e-111 371.2 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) Methyltrans_RNA PF04452.14 ACL96993.1 - 1.3e-55 188.2 0.0 1.5e-55 188.0 0.0 1.0 1 0 0 1 1 1 1 RNA methyltransferase PPK2 PF03976.14 ACL96994.1 - 7.3e-105 349.5 2.9 8.7e-105 349.3 2.9 1.0 1 0 0 1 1 1 1 Polyphosphate kinase 2 (PPK2) Thymidylate_kin PF02223.17 ACL96994.1 - 0.0019 17.9 0.1 0.67 9.6 0.0 2.3 2 0 0 2 2 2 2 Thymidylate kinase DUF1801 PF08818.11 ACL96995.1 - 2e-12 47.4 0.0 2.4e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DU1801) CSTF_C PF14304.6 ACL96995.1 - 0.014 15.0 0.1 0.024 14.2 0.1 1.4 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal DUF2884 PF11101.8 ACL96995.1 - 0.23 10.9 0.0 0.33 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) Peptidase_S10 PF00450.22 ACL96996.1 - 3.8e-17 62.8 0.0 5.1e-14 52.5 0.0 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase Hydrolase_4 PF12146.8 ACL96996.1 - 0.0025 17.1 0.0 0.056 12.7 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ACL96996.1 - 0.026 15.1 3.0 0.036 14.7 2.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF1743 PF08489.11 ACL96996.1 - 0.081 13.0 0.0 0.64 10.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1743) LPAM_1 PF08139.12 ACL96996.1 - 0.18 12.4 0.8 0.47 11.0 0.8 1.8 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site DUF2920 PF11144.8 ACL96996.1 - 0.23 10.6 0.0 0.35 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) DUF4153 PF13687.6 ACL96997.1 - 2.1e-21 76.6 7.1 2.1e-21 76.6 7.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4153) DUF4173 PF13777.6 ACL96997.1 - 6.3e-06 25.7 0.1 6.3e-06 25.7 0.1 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4173) FG-GAP PF01839.23 ACL96997.1 - 0.058 13.5 0.5 0.21 11.8 0.5 1.9 1 0 0 1 1 1 0 FG-GAP repeat DUF4059 PF13268.6 ACL96997.1 - 0.063 13.7 2.6 0.074 13.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) ABC_tran PF00005.27 ACL96998.1 - 4.3e-33 114.7 0.0 6.8e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 ACL96998.1 - 4e-16 59.5 1.9 5.1e-16 59.1 1.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 ACL96998.1 - 3.9e-07 29.7 0.0 0.00014 21.4 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain DEAD PF00270.29 ACL96998.1 - 0.00055 19.8 0.0 0.00093 19.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_16 PF13191.6 ACL96998.1 - 0.0011 19.4 0.1 0.0022 18.4 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 ACL96998.1 - 0.0017 18.3 0.1 0.013 15.3 0.0 2.0 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ACL96998.1 - 0.0023 17.6 0.0 0.0052 16.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 ACL96998.1 - 0.0033 17.7 0.0 0.012 15.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain DUF87 PF01935.17 ACL96998.1 - 0.0056 16.8 0.0 0.0099 16.0 0.0 1.3 1 0 0 1 1 1 1 Helicase HerA, central domain Zeta_toxin PF06414.12 ACL96998.1 - 0.0091 15.3 0.1 0.027 13.7 0.1 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 ACL96998.1 - 0.011 15.9 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 ACL96998.1 - 0.015 15.2 0.2 0.19 11.6 0.0 2.2 1 1 1 2 2 2 0 NTPase AAA_18 PF13238.6 ACL96998.1 - 0.023 15.3 0.0 0.044 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 ACL96998.1 - 0.029 13.5 0.0 0.044 12.9 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit AAA_5 PF07728.14 ACL96998.1 - 0.043 13.8 0.0 0.42 10.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 ACL96998.1 - 0.043 13.5 0.0 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 ACL96998.1 - 0.046 13.4 0.6 0.086 12.6 0.1 1.8 2 1 0 2 2 1 0 AAA domain AAA_15 PF13175.6 ACL96998.1 - 0.049 13.3 0.0 0.065 12.9 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 ACL96998.1 - 0.088 12.7 0.3 0.26 11.2 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_10 PF12846.7 ACL96998.1 - 0.16 10.8 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain DUF485 PF04341.12 ACL96998.1 - 2.8 8.0 5.9 5.2 7.1 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function, DUF485 UbiA PF01040.18 ACL96999.2 - 2.5e-57 194.1 27.8 3.4e-57 193.6 27.8 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF3925 PF13063.6 ACL96999.2 - 0.022 15.0 0.1 0.062 13.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3925) PRA1 PF03208.19 ACL96999.2 - 3.4 7.3 6.6 2.6 7.7 1.6 2.5 2 0 0 2 2 2 0 PRA1 family protein FA_desaturase PF00487.24 ACL97000.2 - 1.7e-41 142.7 13.6 1.7e-41 142.7 13.6 1.8 1 1 1 2 2 2 1 Fatty acid desaturase PrmA PF06325.13 ACL97001.1 - 1.3e-09 37.9 0.1 1.5e-09 37.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 ACL97001.1 - 0.0012 18.4 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 ACL97001.1 - 0.0014 18.4 0.0 0.004 16.9 0.0 1.7 1 1 0 1 1 1 1 Lysine methyltransferase MethyltransfD12 PF02086.15 ACL97001.1 - 0.052 13.2 0.0 0.07 12.8 0.0 1.1 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_25 PF13649.6 ACL97001.1 - 0.064 14.0 0.0 0.1 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain N6_N4_Mtase PF01555.18 ACL97001.1 - 0.22 11.2 0.0 0.32 10.7 0.0 1.2 1 0 0 1 1 1 0 DNA methylase Glyoxalase PF00903.25 ACL97002.1 - 8.3e-07 29.2 0.0 2.7e-06 27.6 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ACL97002.1 - 3.3e-05 24.6 0.0 4.8e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Epimerase PF01370.21 ACL97003.1 - 1.1e-14 54.5 0.0 4.9e-08 32.7 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ACL97003.1 - 6.9e-09 35.9 0.0 5.1e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 NAD(P)H-binding RmlD_sub_bind PF04321.17 ACL97003.1 - 1.1e-06 28.0 0.0 0.0025 16.9 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain 3Beta_HSD PF01073.19 ACL97003.1 - 0.03 13.3 0.0 0.092 11.7 0.0 1.7 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ACL97003.1 - 0.12 11.5 0.0 0.26 10.4 0.0 1.5 2 0 0 2 2 2 0 Male sterility protein YjbR PF04237.13 ACL97004.1 - 5.7e-06 26.8 0.0 7.5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 YjbR Far-17a_AIG1 PF04750.14 ACL97005.1 - 2.1e-06 27.2 4.7 8.4e-06 25.2 4.0 2.1 1 1 1 2 2 2 1 FAR-17a/AIG1-like protein CcmB PF03379.13 ACL97005.1 - 0.31 10.5 10.4 2.2 7.7 1.0 2.3 2 1 0 2 2 2 0 CcmB protein Aldo_ket_red PF00248.21 ACL97006.1 - 6.7e-61 206.0 0.0 8.7e-59 199.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Aldedh PF00171.22 ACL97008.1 - 1.8e-19 69.7 11.9 1.6e-13 50.0 6.8 2.2 1 1 1 2 2 2 2 Aldehyde dehydrogenase family CTP_transf_like PF01467.26 ACL97009.1 - 5.7e-25 88.2 0.0 6.8e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like HIGH_NTase1 PF05636.11 ACL97009.1 - 0.18 11.0 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase RsfS PF02410.15 ACL97010.2 - 1.3e-26 92.9 0.0 1.5e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation SPOUT_MTase PF02590.17 ACL97011.1 - 8.5e-40 136.2 0.0 1e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 Predicted SPOUT methyltransferase sCache_3_2 PF17203.4 ACL97011.1 - 0.063 13.4 0.1 0.26 11.4 0.0 1.8 2 0 0 2 2 2 0 Single cache domain 3 Peptidase_M23 PF01551.22 ACL97012.1 - 1.3e-19 70.2 0.0 2.1e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M23 DUF1003 PF06210.11 ACL97012.1 - 0.093 12.8 0.2 0.29 11.2 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) APG6_N PF17675.1 ACL97012.1 - 3 8.4 9.9 9.6 6.7 2.5 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 ACL97012.1 - 4.8 7.3 10.3 8.2 6.5 1.9 2.5 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein IFT20 PF14931.6 ACL97012.1 - 4.9 7.3 6.2 2.7 8.2 1.2 2.3 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 Peptidase_S41 PF03572.18 ACL97013.1 - 6.6e-55 185.2 0.1 1.1e-54 184.5 0.1 1.3 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 ACL97013.1 - 1.5e-16 60.0 0.2 4.3e-16 58.5 0.2 1.9 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 ACL97013.1 - 1.4e-12 47.8 1.8 1.6e-12 47.6 0.2 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 ACL97013.1 - 2.4e-12 47.0 0.8 1.3e-11 44.7 0.3 2.3 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.6 ACL97013.1 - 9.9e-05 22.2 0.7 0.0002 21.2 0.2 1.9 2 0 0 2 2 2 1 Tricorn protease PDZ domain TSP_NTD PF17804.1 ACL97013.1 - 0.044 14.0 0.0 0.067 13.5 0.0 1.2 1 0 0 1 1 1 0 Tail specific protease N-terminal domain DUF3394 PF11874.8 ACL97013.1 - 0.095 12.4 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) TonB_dep_Rec PF00593.24 ACL97014.1 - 4.6e-39 135.6 28.8 4.6e-39 135.6 28.8 1.7 1 1 1 2 2 2 1 TonB dependent receptor OMP_b-brl_3 PF14905.6 ACL97014.1 - 1e-07 31.3 7.3 9.1e-07 28.2 7.3 2.4 1 1 0 1 1 1 1 Outer membrane protein beta-barrel family Plug PF07715.15 ACL97014.1 - 1.4e-05 25.6 0.2 3.8e-05 24.2 0.2 1.7 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain Nuc_deoxyrib_tr PF05014.15 ACL97014.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase Polysacc_deac_2 PF04748.13 ACL97017.1 - 1.6e-53 181.1 0.0 2e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Divergent polysaccharide deacetylase NUDIX PF00293.28 ACL97018.1 - 1.3e-28 99.6 3.2 1.6e-28 99.4 3.2 1.1 1 0 0 1 1 1 1 NUDIX domain Hydrolase_4 PF12146.8 ACL97019.1 - 3.2e-18 65.9 0.0 3.2e-18 65.9 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ACL97019.1 - 4.1e-16 60.3 0.9 4.1e-16 60.3 0.9 2.1 2 1 0 2 2 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ACL97019.1 - 3.2e-05 23.7 0.1 0.0037 17.0 0.0 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.20 ACL97019.1 - 0.0024 18.0 0.1 0.005 17.0 0.1 1.5 1 0 0 1 1 1 1 Thioesterase domain UPF0227 PF05728.12 ACL97019.1 - 0.0026 17.7 0.0 0.0084 16.1 0.0 1.7 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_4 PF08386.10 ACL97019.1 - 0.0052 16.9 0.0 0.014 15.5 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.21 ACL97019.1 - 0.01 15.3 0.1 0.55 9.7 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family PGAP1 PF07819.13 ACL97019.1 - 0.044 13.5 0.0 0.091 12.5 0.0 1.5 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_5 PF12695.7 ACL97019.1 - 0.064 13.0 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family FSH1 PF03959.13 ACL97019.1 - 0.078 12.6 0.0 0.27 10.9 0.0 1.9 2 1 0 2 2 2 0 Serine hydrolase (FSH1) LCAT PF02450.15 ACL97019.1 - 0.25 10.5 0.0 0.36 10.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 ACL97020.2 - 4e-23 83.2 10.1 4.5e-23 83.0 10.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ACL97020.2 - 3.7e-16 59.1 0.0 4.7e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ACL97020.2 - 9.9e-12 45.0 0.2 3.3e-08 33.5 0.4 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Thioesterase PF00975.20 ACL97020.2 - 6.2e-05 23.2 0.3 0.0001 22.5 0.3 1.3 1 0 0 1 1 1 1 Thioesterase domain Ser_hydrolase PF06821.13 ACL97020.2 - 0.00018 21.4 0.1 0.001 19.0 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase PGAP1 PF07819.13 ACL97020.2 - 0.00044 20.0 0.7 0.00053 19.8 0.1 1.5 2 0 0 2 2 2 1 PGAP1-like protein Palm_thioest PF02089.15 ACL97020.2 - 0.0019 18.1 0.0 0.0021 17.9 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase UPF0227 PF05728.12 ACL97020.2 - 0.0063 16.5 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_8 PF06259.12 ACL97020.2 - 0.013 15.1 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Esterase PF00756.20 ACL97020.2 - 0.016 14.8 0.1 0.023 14.4 0.1 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_5 PF12695.7 ACL97020.2 - 0.041 13.6 0.0 0.61 9.8 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 ACL97020.2 - 0.08 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF676 PF05057.14 ACL97020.2 - 0.17 11.4 0.1 0.29 10.6 0.1 1.6 1 1 0 1 1 1 0 Putative serine esterase (DUF676) DUF2920 PF11144.8 ACL97020.2 - 0.27 10.4 0.0 0.35 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Multi_Drug_Res PF00893.19 ACL97021.2 - 8e-28 97.0 7.9 9.7e-28 96.7 7.9 1.1 1 0 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 ACL97021.2 - 0.055 13.6 13.4 0.084 13.0 13.4 1.3 1 1 0 1 1 1 0 EamA-like transporter family DUF2530 PF10745.9 ACL97021.2 - 0.31 11.3 15.5 2.6 8.3 9.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2530) DUF4229 PF14012.6 ACL97021.2 - 0.98 9.6 9.1 0.98 9.6 1.2 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF4229) Phage_holin_2_1 PF04971.12 ACL97021.2 - 1.9 8.6 5.7 4.4 7.4 5.7 1.6 1 0 0 1 1 1 0 Bacteriophage P21 holin S PepSY_TM PF03929.16 ACL97022.2 - 0.081 12.6 0.5 0.091 12.4 0.5 1.2 1 0 0 1 1 1 0 PepSY-associated TM region ATP-synt_DE_N PF02823.16 ACL97023.1 - 3.1e-27 94.3 0.0 3.4e-27 94.2 0.0 1.0 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain zinc_ribbon_2 PF13240.6 ACL97024.1 - 0.022 14.4 0.1 0.022 14.4 0.1 1.8 2 0 0 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.11 ACL97024.1 - 0.025 14.2 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain DUF4187 PF13821.6 ACL97024.1 - 0.064 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) zf-ribbon_3 PF13248.6 ACL97024.1 - 0.075 12.5 0.8 0.16 11.4 0.0 2.0 3 0 0 3 3 3 0 zinc-ribbon domain Cys_rich_CPXG PF14255.6 ACL97024.1 - 0.086 12.7 0.5 0.32 10.9 0.1 1.9 2 0 0 2 2 2 0 Cysteine-rich CPXCG ATP-synt_ab PF00006.25 ACL97025.1 - 3.1e-62 210.0 0.0 5e-62 209.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 ACL97025.1 - 5.4e-20 71.7 1.0 1.1e-19 70.7 1.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain T3SS_ATPase_C PF18269.1 ACL97025.1 - 0.0098 15.7 1.0 0.08 12.8 1.0 2.2 1 1 0 1 1 1 1 T3SS EscN ATPase C-terminal domain AAA_7 PF12775.7 ACL97025.1 - 0.029 13.9 0.1 0.077 12.5 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase PF06745.13 ACL97025.1 - 0.085 12.2 0.3 0.16 11.3 0.3 1.4 1 0 0 1 1 1 0 KaiC NB-ARC PF00931.22 ACL97025.1 - 0.11 11.7 0.3 0.21 10.7 0.1 1.5 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 ACL97025.1 - 0.11 12.8 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 ACL97025.1 - 0.15 12.5 0.0 0.58 10.5 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 ACL97025.1 - 0.15 10.9 0.2 0.25 10.2 0.2 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 ACL97025.1 - 0.19 12.0 0.1 0.68 10.2 0.0 2.0 3 0 0 3 3 3 0 AAA domain FAP PF07174.11 ACL97025.1 - 8.3 5.8 19.2 0.43 10.0 12.9 1.9 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) ATP-synt PF00231.19 ACL97026.1 - 1e-85 287.9 0.7 1.1e-85 287.7 0.7 1.0 1 0 0 1 1 1 1 ATP synthase ATP-synt_ab PF00006.25 ACL97027.1 - 7.5e-71 238.2 0.0 1.1e-70 237.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 ACL97027.1 - 5.2e-50 169.0 0.1 1.2e-49 167.8 0.1 1.6 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 ACL97027.1 - 4.1e-17 62.5 1.4 4.1e-17 62.5 1.4 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 ACL97027.1 - 0.00037 20.6 0.3 0.002 18.2 0.1 2.2 1 1 1 2 2 2 1 HAS barrel domain HTH_IclR PF09339.10 ACL97027.1 - 0.019 14.8 0.1 0.096 12.5 0.0 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain OSCP PF00213.18 ACL97028.2 - 8.9e-47 159.4 0.1 1e-46 159.2 0.1 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit 4HBT PF03061.22 ACL97029.2 - 0.0016 18.8 0.0 0.0017 18.7 0.0 1.1 1 0 0 1 1 1 1 Thioesterase superfamily Bep_C_terminal PF17841.1 ACL97030.2 - 0.25 11.6 1.8 2.5 8.4 0.4 2.0 2 0 0 2 2 2 0 BID domain of Bartonella effector protein (Bep) Acyl-CoA_dh_1 PF00441.24 ACL97032.1 - 1.7e-40 138.7 1.3 2.8e-40 138.0 1.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ACL97032.1 - 2e-19 69.6 0.0 3.5e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ACL97032.1 - 1.8e-14 54.2 0.0 3.9e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ACL97032.1 - 1.3e-07 32.3 0.2 1.6e-06 28.8 0.1 2.6 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 ACL97032.1 - 0.014 15.1 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal LemA PF04011.12 ACL97033.2 - 2.3e-57 193.0 3.4 2.7e-57 192.8 3.4 1.1 1 0 0 1 1 1 1 LemA family ChaB PF06150.12 ACL97033.2 - 0.039 14.5 0.8 0.094 13.3 0.1 1.9 2 0 0 2 2 2 0 ChaB TPM_phosphatase PF04536.14 ACL97034.1 - 2.3e-39 134.4 0.0 3e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 TPM domain DUF5130 PF17174.4 ACL97034.1 - 0.0018 18.5 0.1 0.003 17.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5130) TPM_phosphatase PF04536.14 ACL97035.1 - 1.1e-10 41.8 0.0 1.3e-07 31.8 0.0 2.2 2 1 0 2 2 2 2 TPM domain CPBP PF02517.16 ACL97036.1 - 7.4e-12 45.5 4.7 7.4e-12 45.5 4.7 2.2 1 1 1 2 2 2 1 CPBP intramembrane metalloprotease DUF1330 PF07045.11 ACL97037.1 - 4.6e-08 33.3 0.0 6.7e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1330) Amidohydro_3 PF07969.11 ACL97038.1 - 2.4e-88 297.7 6.4 2.7e-88 297.5 6.4 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 ACL97038.1 - 3.4e-07 29.9 0.3 0.0044 16.4 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Urease_alpha PF00449.20 ACL97038.1 - 0.0038 17.6 0.3 0.0063 16.8 0.3 1.3 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain TonB_dep_Rec PF00593.24 ACL97039.2 - 6.2e-47 161.5 27.8 8.7e-47 161.1 27.8 1.3 1 0 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 ACL97039.2 - 8.3e-15 55.3 2.2 2.3e-14 53.8 2.2 1.9 1 0 0 1 1 1 1 TonB-dependent Receptor Plug Domain OMP_b-brl_3 PF14905.6 ACL97039.2 - 0.0021 17.1 0.7 0.0021 17.1 0.7 2.5 2 1 0 2 2 2 1 Outer membrane protein beta-barrel family Thiolase_N PF00108.23 ACL97040.1 - 1.5e-59 201.5 7.1 2e-59 201.1 7.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ACL97040.1 - 2.6e-46 156.3 1.4 1e-45 154.4 0.0 2.5 2 1 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ACL97040.1 - 0.0017 17.9 1.6 0.0051 16.4 0.1 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 ACL97040.1 - 0.0024 17.7 1.9 1.1 9.2 0.2 2.6 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF2973 PF11189.8 ACL97041.1 - 0.084 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2973) DNA_pol_A PF00476.20 ACL97042.2 - 2.5e-142 474.4 0.0 3.4e-142 473.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A 5_3_exonuc_N PF02739.16 ACL97042.2 - 6.7e-54 182.1 0.0 1.3e-53 181.2 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain DNA_pol_A_exo1 PF01612.20 ACL97042.2 - 9.1e-34 116.7 0.0 1.5e-33 115.9 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease 5_3_exonuc PF01367.20 ACL97042.2 - 3.7e-30 104.4 0.0 9.6e-30 103.1 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Taq-exonuc PF09281.10 ACL97042.2 - 0.085 12.9 0.7 0.38 10.7 0.1 2.4 2 0 0 2 2 2 0 Taq polymerase, exonuclease CbiG_N PF11760.8 ACL97042.2 - 0.15 12.1 1.8 3.7 7.6 0.1 3.0 2 1 0 2 2 2 0 Cobalamin synthesis G N-terminal CITED PF04487.12 ACL97042.2 - 0.2 11.7 0.0 0.47 10.5 0.0 1.5 1 0 0 1 1 1 0 CITED RQC PF09382.10 ACL97043.2 - 1.7e-22 79.3 0.0 2.9e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 RQC domain HRDC PF00570.23 ACL97043.2 - 2.5e-21 75.4 0.1 9.6e-21 73.5 0.0 2.0 2 0 0 2 2 2 1 HRDC domain DEAD PF00270.29 ACL97043.2 - 4.5e-17 62.4 0.0 7.5e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ACL97043.2 - 1.3e-16 60.9 0.0 6.3e-14 52.3 0.0 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 ACL97043.2 - 6.6e-09 36.4 0.1 1.3e-08 35.5 0.1 1.5 1 0 0 1 1 1 1 RecQ zinc-binding DUF883 PF05957.13 ACL97044.1 - 5.2e-09 36.6 2.0 6.4e-09 36.3 2.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) DUF350 PF03994.14 ACL97044.1 - 0.047 13.8 0.1 0.086 13.0 0.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF350) LEA_4 PF02987.16 ACL97044.1 - 1.3 9.2 8.9 0.21 11.7 4.8 1.7 2 0 0 2 2 2 0 Late embryogenesis abundant protein MmcB-like PF06319.12 ACL97045.1 - 1.6e-49 167.4 0.0 1.9e-49 167.1 0.0 1.0 1 0 0 1 1 1 1 DNA repair protein MmcB-like EamA PF00892.20 ACL97046.1 - 5.7e-18 65.4 34.0 1.1e-15 58.0 13.2 2.2 2 1 0 2 2 2 2 EamA-like transporter family Inositol_P PF00459.25 ACL97047.1 - 6.9e-48 163.5 0.0 8.5e-48 163.2 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF3553 PF12073.8 ACL97048.2 - 3.1e-26 90.8 0.6 3.5e-26 90.7 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3553) Tudor_1_RapA PF18339.1 ACL97048.2 - 0.00078 19.3 0.1 0.0016 18.4 0.0 1.5 1 1 1 2 2 2 1 RapA N-terminal Tudor like domain 1 HPTransfase PF10090.9 ACL97049.2 - 5.2e-31 107.0 0.6 5.2e-31 107.0 0.6 1.7 2 0 0 2 2 2 1 Histidine phosphotransferase C-terminal domain Response_reg PF00072.24 ACL97050.1 - 2.8e-29 101.5 0.0 3.1e-29 101.4 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain CheR PF01739.18 ACL97051.1 - 4.1e-43 147.2 0.0 5.3e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain CheR_N PF03705.15 ACL97051.1 - 8.4e-08 31.8 0.0 1.8e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain Methyltransf_23 PF13489.6 ACL97051.1 - 2.8e-06 27.3 0.0 4.1e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ACL97051.1 - 0.003 17.4 0.0 0.047 13.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ACL97051.1 - 0.0039 17.9 0.0 0.07 13.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Entericidin PF08085.11 ACL97052.1 - 9e-09 35.1 2.8 9e-09 35.1 2.8 1.5 2 0 0 2 2 2 1 Entericidin EcnA/B family DUF4148 PF13663.6 ACL97052.1 - 0.099 12.8 0.7 0.1 12.8 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) HisKA_2 PF07568.12 ACL97053.1 - 1.8e-26 92.0 0.2 5e-26 90.6 0.1 1.8 2 0 0 2 2 2 1 Histidine kinase HWE_HK PF07536.14 ACL97053.1 - 1.4e-06 28.9 0.3 3.7e-06 27.5 0.3 1.8 1 0 0 1 1 1 1 HWE histidine kinase dCache_1 PF02743.18 ACL97053.1 - 7.7e-06 25.9 0.0 2e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Cache domain HATPase_c_2 PF13581.6 ACL97053.1 - 0.00023 21.1 0.0 0.00055 19.9 0.0 1.7 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c PF02518.26 ACL97053.1 - 0.00058 20.3 0.1 0.02 15.4 0.1 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 ACL97053.1 - 0.0031 17.9 0.2 0.015 15.7 0.0 2.3 2 0 0 2 2 2 1 HAMP domain TMEM191C PF15194.6 ACL97053.1 - 0.69 10.1 10.2 0.33 11.1 0.5 3.9 4 0 0 4 4 4 0 TMEM191C family Sigma70_r4_2 PF08281.12 ACL97054.1 - 4.7e-15 55.0 0.1 8.5e-15 54.2 0.1 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 ACL97054.1 - 1.4e-14 53.6 0.6 1.4e-14 53.6 0.6 1.8 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_ECF PF07638.11 ACL97054.1 - 3.4e-06 27.1 0.2 3.4e-06 27.1 0.2 1.5 2 0 0 2 2 2 1 ECF sigma factor Sigma70_r4 PF04545.16 ACL97054.1 - 2.6e-05 23.6 0.0 4.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 DUF2859 PF11072.8 ACL97054.1 - 0.022 14.5 0.3 2.6 7.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2859) Ribosomal_L39 PF00832.20 ACL97054.1 - 0.025 14.2 0.5 0.045 13.4 0.5 1.4 1 0 0 1 1 1 0 Ribosomal L39 protein GerE PF00196.19 ACL97054.1 - 0.08 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family NepR PF18557.1 ACL97055.2 - 6e-15 54.6 0.1 9.4e-15 54.0 0.1 1.3 1 0 0 1 1 1 1 Anti-sigma factor NepR Response_reg PF00072.24 ACL97056.1 - 2.2e-12 47.1 0.0 3.6e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Sigma70_r4_2 PF08281.12 ACL97056.1 - 8.1e-05 22.2 0.0 0.00033 20.3 0.0 2.0 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_ECF PF07638.11 ACL97056.1 - 0.022 14.7 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 ECF sigma factor Lipocalin_2 PF08212.12 ACL97057.2 - 2.7e-51 173.3 0.0 3.1e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 ACL97057.2 - 0.024 14.8 0.0 0.032 14.4 0.0 1.2 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family Ald_deCOase PF11266.8 ACL97058.1 - 1.4e-06 28.2 0.1 6e-06 26.1 0.1 2.1 1 1 0 1 1 1 1 Long-chain fatty aldehyde decarbonylase AurF PF11583.8 ACL97058.1 - 0.00034 20.0 0.6 0.25 10.6 0.0 2.5 2 1 1 3 3 3 3 P-aminobenzoate N-oxygenase AurF SIR2 PF02146.17 ACL97059.1 - 3.7e-42 144.2 0.0 4.5e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Sir2 family Methyltransf_11 PF08241.12 ACL97060.1 - 3.9e-24 85.1 0.0 5.8e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ACL97060.1 - 4.6e-21 75.4 0.0 5.8e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ACL97060.1 - 4.2e-18 65.8 0.0 6.7e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ACL97060.1 - 5.3e-12 45.8 0.0 6.1e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ACL97060.1 - 2.4e-11 44.3 0.0 3.5e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ACL97060.1 - 2.2e-08 33.8 0.0 2.7e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 ACL97060.1 - 7.1e-06 25.7 0.0 1e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_29 PF03141.16 ACL97060.1 - 0.00075 18.2 0.0 0.00095 17.8 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.15 ACL97060.1 - 0.033 14.0 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_9 PF08003.11 ACL97060.1 - 0.037 12.9 0.0 0.051 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) SWIM PF04434.17 ACL97061.1 - 2.6e-07 30.2 0.2 5.2e-07 29.2 0.2 1.5 1 0 0 1 1 1 1 SWIM zinc finger Zincin_1 PF06262.11 ACL97062.2 - 1.1e-33 115.2 0.2 1.4e-33 114.8 0.2 1.1 1 0 0 1 1 1 1 Zincin-like metallopeptidase DUF4953 PF16313.5 ACL97062.2 - 0.036 13.3 0.3 0.053 12.7 0.3 1.2 1 0 0 1 1 1 0 Met-zincin Peptidase_M10 PF00413.24 ACL97062.2 - 0.037 13.9 0.2 0.055 13.3 0.2 1.2 1 0 0 1 1 1 0 Matrixin Reprolysin_3 PF13582.6 ACL97062.2 - 0.12 12.9 0.2 0.16 12.5 0.2 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 ACL97062.2 - 0.31 10.7 0.6 0.39 10.3 0.6 1.1 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 ACL97062.2 - 0.41 10.2 1.6 0.58 9.7 1.6 1.1 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase HATPase_c PF02518.26 ACL97063.1 - 5.5e-23 81.6 0.0 1.1e-22 80.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_7 PF12860.7 ACL97063.1 - 1.5e-22 79.9 0.0 2.6e-10 40.5 0.0 3.7 3 0 0 3 3 3 2 PAS fold HisKA PF00512.25 ACL97063.1 - 6.3e-15 55.0 0.3 3.5e-14 52.6 0.1 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 ACL97063.1 - 4.1e-10 39.9 5.9 0.0073 16.6 0.2 4.7 4 2 0 4 4 4 3 PAS fold PAS_8 PF13188.7 ACL97063.1 - 6.6e-08 32.4 0.1 0.014 15.4 0.0 3.6 3 0 0 3 3 3 2 PAS domain HATPase_c_2 PF13581.6 ACL97063.1 - 0.0049 16.8 0.3 0.027 14.4 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain PAS PF00989.25 ACL97063.1 - 0.013 15.5 0.1 7.4 6.6 0.0 3.6 3 1 0 3 3 3 0 PAS fold Vir_act_alpha_C PF10400.9 ACL97063.1 - 0.29 11.8 1.9 1 10.1 0.0 2.6 3 0 0 3 3 3 0 Virulence activator alpha C-term Semialdhyde_dhC PF02774.18 ACL97064.1 - 8.8e-48 162.8 0.0 1.3e-47 162.3 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 ACL97064.1 - 1.7e-32 112.4 0.1 2.7e-32 111.7 0.1 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 ACL97064.1 - 0.0026 17.4 0.0 0.076 12.6 0.0 2.2 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain UPF0126 PF03458.13 ACL97064.1 - 0.0037 17.1 0.1 0.011 15.5 0.1 1.8 1 0 0 1 1 1 1 UPF0126 domain TauE PF01925.19 ACL97065.1 - 9.4e-29 100.7 32.8 1.1e-28 100.5 32.8 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE 7tm_1 PF00001.21 ACL97065.1 - 2.3 7.5 4.9 0.68 9.2 2.0 1.6 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) HlyIII PF03006.20 ACL97066.1 - 1.3e-19 70.8 11.7 1.7e-19 70.4 11.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related Patatin PF01734.22 ACL97067.1 - 5.8e-16 59.3 1.2 1.2e-15 58.3 1.2 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase Beta-lactamase PF00144.24 ACL97068.1 - 2.9e-60 204.3 8.3 4.7e-60 203.6 6.0 2.3 3 0 0 3 3 3 1 Beta-lactamase DUF3471 PF11954.8 ACL97068.1 - 2.8e-29 101.6 0.0 1.3e-13 51.3 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3471) Zn-ribbon_8 PF09723.10 ACL97069.2 - 3.6e-05 23.8 1.2 6.5e-05 23.0 1.2 1.4 1 0 0 1 1 1 1 Zinc ribbon domain DNA_RNApol_7kD PF03604.13 ACL97069.2 - 0.0014 18.2 0.9 0.16 11.7 0.0 2.2 2 0 0 2 2 2 2 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.7 ACL97069.2 - 0.0021 18.0 0.3 0.0032 17.5 0.3 1.2 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_4 PF13717.6 ACL97069.2 - 0.008 16.1 0.5 0.9 9.5 0.0 2.4 2 0 0 2 2 2 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 ACL97069.2 - 0.0081 15.5 1.0 0.24 10.8 0.0 2.3 2 0 0 2 2 2 1 zinc-ribbon domain HypA PF01155.19 ACL97069.2 - 0.031 14.3 0.2 0.042 13.9 0.2 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Prok-RING_1 PF14446.6 ACL97069.2 - 0.098 12.6 0.7 0.16 11.9 0.7 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DUF2219 PF09982.9 ACL97070.1 - 3.9e-11 42.7 0.3 5.7e-11 42.2 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2219) Ribonuc_red_lgC PF02867.15 ACL97072.1 - 7.3e-107 358.1 0.0 6.4e-71 239.5 0.0 2.1 1 1 1 2 2 2 2 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 ACL97072.1 - 2e-15 56.6 0.0 3.5e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain HTH_Tnp_1_2 PF13022.6 ACL97072.1 - 0.14 12.3 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase OMP_b-brl PF13505.6 ACL97074.2 - 4.9e-19 69.1 4.3 7.4e-19 68.6 4.3 1.2 1 0 0 1 1 1 1 Outer membrane protein beta-barrel domain OmpA PF00691.20 ACL97074.2 - 5.2e-19 68.4 0.0 9e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 OmpA family Opacity PF02462.15 ACL97074.2 - 2.8e-06 27.4 0.1 1.2e-05 25.4 0.0 2.1 2 1 0 2 2 2 1 Opacity family porin protein Surface_Ag_2 PF01617.17 ACL97074.2 - 0.00026 20.5 0.0 0.00048 19.6 0.0 1.4 1 0 0 1 1 1 1 Surface antigen PhrC_PhrF PF11131.8 ACL97074.2 - 0.19 11.4 1.2 0.45 10.1 1.2 1.6 1 0 0 1 1 1 0 Rap-phr extracellular signalling Methyltransf_31 PF13847.6 ACL97075.2 - 1.9e-21 76.4 0.0 2.5e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ACL97075.2 - 6.4e-21 74.9 0.1 1e-20 74.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ACL97075.2 - 3.3e-19 69.3 0.0 5.3e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ACL97075.2 - 9.9e-18 64.3 0.0 1.5e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 ACL97075.2 - 1.4e-13 51.0 0.0 1.9e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ACL97075.2 - 4.7e-13 49.7 0.0 7.4e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ACL97075.2 - 1.4e-08 34.8 0.0 1.8e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 ACL97075.2 - 3.4e-07 29.8 0.0 4.5e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 ACL97075.2 - 2.5e-05 23.9 0.0 4.4e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.18 ACL97075.2 - 7e-05 22.6 0.1 0.0015 18.2 0.1 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.17 ACL97075.2 - 0.0024 17.4 0.0 0.0039 16.7 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase NodS PF05401.11 ACL97075.2 - 0.0067 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) FtsJ PF01728.19 ACL97075.2 - 0.0069 16.5 0.0 0.045 13.8 0.1 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase GCD14 PF08704.10 ACL97075.2 - 0.012 15.4 0.0 0.017 14.8 0.0 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit PrmA PF06325.13 ACL97075.2 - 0.032 13.6 0.1 0.048 13.1 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 ACL97075.2 - 0.052 13.5 0.0 0.078 13.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 ACL97075.2 - 0.064 12.2 0.0 0.12 11.3 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_2 PF00891.18 ACL97075.2 - 0.086 12.1 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain RrnaAD PF00398.20 ACL97075.2 - 0.17 10.9 0.0 0.22 10.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DOT1 PF08123.13 ACL97075.2 - 0.27 10.8 0.0 0.42 10.1 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Na_H_Exchanger PF00999.21 ACL97076.1 - 2.1e-59 201.3 42.6 2.9e-59 200.8 42.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 ACL97076.1 - 4.1e-22 78.6 0.1 8.3e-22 77.6 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain ApbA PF02558.16 ACL97076.1 - 0.0095 15.6 1.4 0.018 14.7 0.0 2.1 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA HTH_31 PF13560.6 ACL97077.2 - 1.5e-06 28.5 0.3 1.7e-06 28.2 0.3 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 ACL97077.2 - 4e-06 26.8 0.0 5.2e-06 26.4 0.0 1.3 1 1 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 ACL97077.2 - 0.00038 20.4 0.0 0.00062 19.7 0.0 1.5 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 ACL97077.2 - 0.0056 16.5 0.0 0.093 12.6 0.0 2.0 1 1 1 2 2 2 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 ACL97077.2 - 0.007 15.9 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_Crp_2 PF13545.6 ACL97077.2 - 0.0096 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_23 PF13384.6 ACL97077.2 - 0.012 15.4 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_24 PF13412.6 ACL97077.2 - 0.022 14.3 0.0 0.044 13.3 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 ACL97077.2 - 0.025 14.5 0.1 0.054 13.5 0.0 1.6 2 0 0 2 2 2 0 HTH domain LacI PF00356.21 ACL97077.2 - 0.036 13.9 0.3 0.049 13.4 0.2 1.5 1 1 0 1 1 1 0 Bacterial regulatory proteins, lacI family HTH_IclR PF09339.10 ACL97077.2 - 0.054 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain MarR_2 PF12802.7 ACL97077.2 - 0.089 12.7 0.1 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 MarR family MerR PF00376.23 ACL97077.2 - 0.14 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 MerR family regulatory protein MaoC_dehydratas PF01575.19 ACL97078.1 - 2.1e-22 78.9 0.2 2.8e-22 78.6 0.2 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 ACL97078.1 - 8.5e-13 48.6 0.3 1.7e-12 47.6 0.3 1.5 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase 4HBT PF03061.22 ACL97078.1 - 0.0001 22.5 0.3 0.00029 21.1 0.3 1.9 1 1 0 1 1 1 1 Thioesterase superfamily DUF3581 PF12119.8 ACL97078.1 - 0.094 12.1 0.1 0.2 11.0 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3581) DUF2946 PF11162.8 ACL97079.1 - 0.00023 21.8 8.3 0.00028 21.5 8.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2946) MSP1a PF11670.8 ACL97079.1 - 0.18 11.0 3.3 0.23 10.7 3.3 1.3 1 1 0 1 1 1 0 Major surface protein 1a (MSP1a) TonB_dep_Rec PF00593.24 ACL97080.2 - 2.3e-32 113.5 37.3 2.3e-32 113.5 36.4 1.4 1 1 0 1 1 1 1 TonB dependent receptor Plug PF07715.15 ACL97080.2 - 2.3e-12 47.4 0.6 2.3e-12 47.4 0.6 2.5 2 0 0 2 2 2 1 TonB-dependent Receptor Plug Domain PepSY_TM PF03929.16 ACL97081.1 - 1.9e-64 218.1 17.1 1.9e-64 218.1 17.1 1.8 2 0 0 2 2 2 1 PepSY-associated TM region Ni_hydr_CYTB PF01292.20 ACL97081.1 - 0.00013 21.6 14.5 0.8 9.3 3.5 3.7 3 1 0 3 3 3 3 Prokaryotic cytochrome b561 PepSY_TM_like_2 PF16357.5 ACL97081.1 - 0.0023 18.0 1.7 0.0023 18.0 1.7 2.3 2 1 0 2 2 2 1 Putative PepSY_TM-like DUF4405 PF14358.6 ACL97081.1 - 0.019 15.5 10.4 0.047 14.2 0.4 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4405) PepSY PF03413.19 ACL97081.1 - 0.079 13.5 1.4 0.14 12.8 0.7 1.8 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain DUF4079 PF13301.6 ACL97081.1 - 0.16 12.2 8.4 4.6 7.4 0.1 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF4079) PCuAC PF04314.13 ACL97082.1 - 1.1e-32 112.1 0.1 1.4e-32 111.7 0.1 1.1 1 0 0 1 1 1 1 Copper chaperone PCu(A)C SCO1-SenC PF02630.14 ACL97083.1 - 2.4e-55 186.1 0.0 2.8e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 ACL97083.1 - 1.6e-07 31.3 0.0 2.3e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 ACL97083.1 - 0.0026 18.0 0.0 0.0035 17.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 ACL97083.1 - 0.042 13.6 0.0 0.053 13.2 0.0 1.1 1 0 0 1 1 1 0 Redoxin Peptidase_M13_N PF05649.13 ACL97084.1 - 4.3e-104 349.2 0.0 5.3e-104 348.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 ACL97084.1 - 3.7e-69 232.5 0.0 9.1e-69 231.2 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M13 CSG2 PF16965.5 ACL97085.1 - 0.041 12.8 0.5 0.065 12.2 0.5 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator UCR_UQCRX_QCR9 PF05365.12 ACL97085.1 - 2.6 8.1 4.8 1.3 9.0 1.7 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like 7TMR-DISM_7TM PF07695.11 ACL97085.1 - 3.2 7.6 15.7 8.4 6.2 12.3 2.7 2 1 0 2 2 2 0 7TM diverse intracellular signalling HTH_18 PF12833.7 ACL97086.2 - 2.6e-14 53.2 0.4 4.9e-14 52.3 0.2 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 ACL97086.2 - 0.0028 17.7 0.0 1.4 9.1 0.0 2.4 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family DUF484 PF04340.12 ACL97086.2 - 0.017 14.8 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF484 DUF1465 PF07323.12 ACL97086.2 - 0.077 12.8 1.0 0.28 11.0 1.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1465) Penicillinase_R PF03965.16 ACL97087.1 - 4e-34 117.4 0.0 4.4e-34 117.3 0.0 1.0 1 0 0 1 1 1 1 Penicillinase repressor DUF3489 PF11994.8 ACL97087.1 - 0.041 13.9 0.0 0.064 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) PaaX PF07848.12 ACL97087.1 - 0.097 12.9 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 PaaX-like protein Peptidase_M56 PF05569.11 ACL97088.1 - 3.5e-76 256.3 0.0 4.4e-76 255.9 0.0 1.1 1 0 0 1 1 1 1 BlaR1 peptidase M56 TonB_C PF03544.14 ACL97088.1 - 1.5e-11 44.5 0.1 3.1e-11 43.6 0.0 1.6 2 0 0 2 2 2 1 Gram-negative bacterial TonB protein C-terminal Sbt_1 PF05982.12 ACL97089.2 - 1.8e-97 326.4 28.8 2e-97 326.2 28.8 1.0 1 0 0 1 1 1 1 Na+-dependent bicarbonate transporter superfamily DUF3007 PF11460.8 ACL97089.2 - 5.8 7.2 6.6 2.9 8.2 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3007) LysR_substrate PF03466.20 ACL97090.1 - 1.1e-32 113.1 8.5 1.7e-32 112.5 8.5 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 ACL97090.1 - 1.8e-20 72.6 1.6 6.9e-20 70.8 0.5 2.4 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_AsnC-type PF13404.6 ACL97090.1 - 0.19 11.6 2.4 0.31 10.9 0.4 2.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HisG PF01634.18 ACL97091.1 - 4.1e-34 117.9 0.0 5.9e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase tRNA-synt_His PF13393.6 ACL97092.3 - 3.1e-29 102.2 2.7 7.2e-18 64.9 0.0 2.1 1 1 1 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_His PF13393.6 ACL97093.1 - 4.8e-46 157.4 0.0 6.1e-46 157.1 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 ACL97093.1 - 3.3e-11 43.2 0.0 9.2e-11 41.8 0.0 1.8 1 1 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 ACL97093.1 - 3.4e-06 27.1 0.0 7.7e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 ACL97093.1 - 0.13 11.7 0.0 0.29 10.6 0.0 1.4 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) DUF4065 PF13274.6 ACL97095.1 - 1.6e-16 61.2 0.0 3.9e-16 59.9 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4065) GIY-YIG PF01541.24 ACL97098.1 - 6.7e-10 39.1 0.1 9.1e-10 38.7 0.1 1.1 1 0 0 1 1 1 1 GIY-YIG catalytic domain DoxX_2 PF13564.6 ACL97099.1 - 5.6e-12 45.7 5.7 7.7e-12 45.2 5.7 1.2 1 0 0 1 1 1 1 DoxX-like family DUF5560 PF17715.1 ACL97100.1 - 0.12 11.8 6.8 0.18 11.3 6.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5560) BATS PF06968.13 ACL97101.1 - 4.5e-19 68.4 0.0 1.1e-18 67.2 0.0 1.7 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 ACL97101.1 - 1.7e-14 54.6 0.0 2.5e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily CHAD PF05235.14 ACL97102.1 - 3.7e-44 151.4 23.4 7.6e-44 150.4 23.4 1.5 1 0 0 1 1 1 1 CHAD domain CYTH PF01928.21 ACL97102.1 - 2.8e-31 108.8 0.0 5.7e-31 107.8 0.0 1.6 1 0 0 1 1 1 1 CYTH domain Fer2 PF00111.27 ACL97104.1 - 1.5e-15 56.9 0.8 1.8e-15 56.7 0.8 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Pyr_redox_2 PF07992.14 ACL97105.2 - 7.8e-64 215.7 0.2 9.5e-64 215.4 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 ACL97105.2 - 1.7e-32 111.8 1.9 4.1e-32 110.6 0.1 2.5 3 0 0 3 3 3 1 Reductase C-terminal Pyr_redox PF00070.27 ACL97105.2 - 4.5e-23 81.6 0.2 4.2e-17 62.5 0.1 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ACL97105.2 - 1.6e-05 24.2 5.0 0.045 12.8 0.1 3.2 2 2 1 3 3 3 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 ACL97105.2 - 1.9e-05 24.8 8.6 0.03 14.6 0.8 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 ACL97105.2 - 2.6e-05 23.6 3.3 0.00064 19.1 0.0 2.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 ACL97105.2 - 0.00034 20.9 4.4 0.86 9.9 0.2 3.3 2 1 1 3 3 3 2 TrkA-N domain GIDA PF01134.22 ACL97105.2 - 0.00048 19.3 7.7 0.034 13.2 0.9 3.2 4 0 0 4 4 4 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 ACL97105.2 - 0.00099 18.4 0.6 0.016 14.5 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ACL97105.2 - 0.0012 18.5 14.6 1.1 8.7 0.7 4.1 3 1 1 4 4 4 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ACL97105.2 - 0.0062 15.8 6.7 0.069 12.4 1.4 2.3 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 ACL97105.2 - 0.0088 14.8 5.4 0.087 11.5 0.7 3.5 3 1 1 4 4 4 1 HI0933-like protein 2-Hacid_dh_C PF02826.19 ACL97105.2 - 0.014 14.8 0.8 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 ACL97105.2 - 0.016 14.7 2.5 0.59 9.7 0.0 2.8 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain XdhC_C PF13478.6 ACL97105.2 - 0.033 14.7 0.9 6.1 7.4 0.1 2.5 2 1 0 2 2 2 0 XdhC Rossmann domain Trp_halogenase PF04820.14 ACL97105.2 - 0.13 11.1 6.6 1.5 7.5 0.1 3.5 3 1 1 4 4 4 0 Tryptophan halogenase NAD_binding_7 PF13241.6 ACL97105.2 - 0.17 12.4 2.1 1.7 9.2 0.1 2.6 3 0 0 3 3 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 ACL97105.2 - 0.27 10.3 12.1 1.7 7.6 2.2 3.5 2 1 1 4 4 4 0 FAD binding domain 3HCDH_N PF02737.18 ACL97105.2 - 0.52 10.2 2.4 11 5.9 0.3 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 ACL97105.2 - 1.6 8.7 4.8 19 5.2 0.0 3.2 4 0 0 4 4 4 0 FAD-NAD(P)-binding Fer2_3 PF13085.6 ACL97106.1 - 8.4e-33 112.7 0.0 1.3e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 ACL97106.1 - 1e-09 38.8 3.1 1e-09 38.8 3.1 1.8 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 ACL97106.1 - 2.8e-08 34.1 5.6 2.8e-08 34.1 5.6 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 ACL97106.1 - 6.1e-08 32.7 2.3 6.1e-08 32.7 2.3 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 ACL97106.1 - 0.00049 20.6 5.1 0.00049 20.6 5.1 2.5 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 ACL97106.1 - 0.0018 18.4 5.0 0.0018 18.4 5.0 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 ACL97106.1 - 0.0041 17.1 1.5 0.011 15.7 0.1 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.6 ACL97106.1 - 0.013 15.7 0.4 1.2 9.4 0.1 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 ACL97106.1 - 0.81 10.7 11.6 2.8 9.0 0.1 2.8 3 0 0 3 3 3 0 4Fe-4S double cluster binding domain FAD_binding_2 PF00890.24 ACL97107.2 - 1.8e-129 432.5 4.8 2.3e-129 432.1 4.8 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 ACL97107.2 - 7.3e-43 145.6 0.2 1.1e-42 145.1 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 ACL97107.2 - 8.8e-06 25.1 1.1 7.4e-05 22.1 1.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ACL97107.2 - 4.3e-05 22.8 2.8 0.0016 17.6 3.2 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 ACL97107.2 - 0.00014 21.4 5.7 0.051 12.9 5.6 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 ACL97107.2 - 0.00044 19.6 0.6 0.0049 16.1 0.2 2.3 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 ACL97107.2 - 0.0053 16.4 0.7 0.021 14.4 0.2 2.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ACL97107.2 - 0.02 14.1 0.4 1.4 8.1 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ACL97107.2 - 0.025 13.3 2.1 0.042 12.5 0.8 1.8 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.19 ACL97107.2 - 0.026 13.8 0.7 0.054 12.7 0.7 1.6 1 0 0 1 1 1 0 FAD binding domain Sdh_cyt PF01127.22 ACL97108.3 - 2.3e-16 59.9 2.0 3.3e-16 59.4 2.0 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit CybS PF05328.12 ACL97108.3 - 2.3e-05 24.1 2.2 6.7e-05 22.6 2.2 1.6 1 1 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Sdh_cyt PF01127.22 ACL97109.1 - 2.4e-25 88.9 3.5 2.7e-25 88.7 3.5 1.0 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Fumarate_red_C PF02300.17 ACL97109.1 - 0.053 13.6 3.8 0.12 12.4 3.8 1.7 1 1 0 1 1 1 0 Fumarate reductase subunit C NUDIX PF00293.28 ACL97110.1 - 1.5e-05 25.1 0.0 2.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain AFG1_ATPase PF03969.16 ACL97111.1 - 1.3e-156 521.0 0.0 1.5e-156 520.8 0.0 1.0 1 0 0 1 1 1 1 AFG1-like ATPase AAA_16 PF13191.6 ACL97111.1 - 0.0034 17.8 1.3 0.64 10.4 0.1 3.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ACL97111.1 - 0.028 14.7 0.0 0.06 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Acyltransferase PF01553.21 ACL97112.2 - 1.3e-13 50.7 0.0 1.9e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase TsaE PF02367.17 ACL97113.1 - 9.9e-36 122.5 0.0 1.1e-35 122.3 0.0 1.0 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 ACL97113.1 - 0.00018 22.0 0.0 0.00022 21.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 ACL97113.1 - 0.00021 21.7 0.0 0.00026 21.4 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 ACL97113.1 - 0.00071 19.3 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 ACL97113.1 - 0.0028 18.2 0.0 0.0033 18.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ACL97113.1 - 0.0028 17.9 0.0 0.0038 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 ACL97113.1 - 0.004 17.7 0.0 0.005 17.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 ACL97113.1 - 0.0048 16.0 0.0 0.0066 15.5 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_33 PF13671.6 ACL97113.1 - 0.0054 16.9 0.0 0.0075 16.4 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 ACL97113.1 - 0.0055 16.7 0.0 0.0081 16.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AraC_binding_2 PF14525.6 ACL97113.1 - 0.0056 16.4 2.8 0.063 13.0 0.4 2.0 2 0 0 2 2 2 1 AraC-binding-like domain AAA PF00004.29 ACL97113.1 - 0.0075 16.7 0.0 0.011 16.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 ACL97113.1 - 0.0094 15.7 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 ACL97113.1 - 0.016 15.3 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 ACL97113.1 - 0.016 14.8 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 ACL97113.1 - 0.018 14.9 0.0 0.025 14.5 0.0 1.2 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 ACL97113.1 - 0.021 15.2 0.0 0.029 14.8 0.0 1.2 1 0 0 1 1 1 0 RNA helicase APS_kinase PF01583.20 ACL97113.1 - 0.024 14.5 0.0 0.05 13.5 0.0 1.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_25 PF13481.6 ACL97113.1 - 0.031 13.9 0.7 0.059 12.9 0.7 1.5 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 ACL97113.1 - 0.041 13.8 0.0 0.051 13.5 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase Mg_chelatase PF01078.21 ACL97113.1 - 0.042 13.2 0.0 0.062 12.7 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 ACL97113.1 - 0.058 13.3 0.0 0.078 12.9 0.0 1.2 1 0 0 1 1 1 0 NTPase dNK PF01712.19 ACL97113.1 - 0.076 12.9 0.0 0.089 12.6 0.0 1.1 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_30 PF13604.6 ACL97113.1 - 0.09 12.5 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ACL97113.1 - 0.099 12.7 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 ACL97113.1 - 0.11 12.7 0.1 0.19 12.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ACL97113.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_PrkA PF08298.11 ACL97113.1 - 0.15 11.0 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 PrkA AAA domain MeaB PF03308.16 ACL97113.1 - 0.21 10.5 0.1 0.26 10.3 0.1 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB APH PF01636.23 ACL97114.1 - 2.3e-29 103.0 12.0 3.7e-29 102.3 12.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 ACL97114.1 - 8.3e-05 22.0 0.0 0.00036 19.9 0.0 1.9 2 0 0 2 2 2 1 Ecdysteroid kinase DUF1679 PF07914.11 ACL97114.1 - 0.00025 20.1 0.0 0.00033 19.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 ACL97114.1 - 0.026 14.1 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF2252 PF10009.9 ACL97114.1 - 0.058 12.4 0.1 0.088 11.9 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) NTP_transf_3 PF12804.7 ACL97115.1 - 4.5e-15 56.4 1.8 5.2e-15 56.2 1.8 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 ACL97115.1 - 9.9e-14 51.5 0.0 1.9e-13 50.6 0.0 1.4 2 0 0 2 2 2 1 Nucleotidyl transferase IspD PF01128.19 ACL97115.1 - 3.8e-05 23.5 0.1 6e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase PDDEXK_1 PF12705.7 ACL97116.1 - 3.1e-24 86.3 0.0 6.3e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily UvrD-helicase PF00580.21 ACL97117.1 - 1.9e-48 165.6 0.0 3.3e-48 164.8 0.0 1.4 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 ACL97117.1 - 1.4e-18 67.7 0.0 4.7e-18 65.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain UvrD_C PF13361.6 ACL97117.1 - 3.6e-18 66.1 0.0 7.7e-17 61.7 0.0 2.1 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain PDDEXK_1 PF12705.7 ACL97117.1 - 5.2e-14 52.8 0.2 2.5e-13 50.5 0.0 2.2 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily UvrD_C_2 PF13538.6 ACL97117.1 - 5.6e-10 38.9 0.2 0.00011 21.9 0.2 2.9 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 ACL97117.1 - 0.0068 16.2 0.2 2.6 7.7 0.1 3.1 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 ACL97117.1 - 0.018 14.8 0.5 0.063 13.0 0.2 2.2 2 0 0 2 2 2 0 AAA domain AAA_12 PF13087.6 ACL97117.1 - 0.26 10.9 0.0 1.1 8.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Thioredoxin PF00085.20 ACL97118.2 - 1.1e-33 115.2 0.0 1.3e-33 115.1 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ACL97118.2 - 1.1e-10 41.9 0.1 4.7e-10 39.9 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ACL97118.2 - 7e-09 35.9 0.0 1.2e-06 28.7 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 ACL97118.2 - 2.9e-06 27.2 0.0 3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ACL97118.2 - 3.1e-05 23.7 0.0 6.1e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 ACL97118.2 - 0.00011 22.3 0.0 0.00017 21.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.6 ACL97118.2 - 0.00052 20.0 0.0 0.00072 19.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_9 PF14595.6 ACL97118.2 - 0.00076 19.2 0.0 0.00083 19.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DUF836 PF05768.14 ACL97118.2 - 0.001 19.4 0.0 0.0013 19.1 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) TraF PF13728.6 ACL97118.2 - 0.0015 18.4 0.0 0.0018 18.1 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein DIM1 PF02966.16 ACL97118.2 - 0.0018 18.1 0.0 0.0021 17.9 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 OST3_OST6 PF04756.13 ACL97118.2 - 0.019 14.3 0.0 0.024 14.0 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family HyaE PF07449.11 ACL97118.2 - 0.021 14.8 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DSBA PF01323.20 ACL97118.2 - 0.067 13.0 0.2 1.5 8.5 0.0 2.2 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Mur_ligase_M PF08245.12 ACL97120.1 - 1.4e-08 35.0 0.0 2.6e-08 34.1 0.0 1.5 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 ACL97120.1 - 0.11 12.8 0.0 0.32 11.3 0.0 1.9 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Carboxyl_trans PF01039.22 ACL97121.1 - 1.5e-17 63.4 0.3 1.9e-17 63.1 0.3 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain zf-ACC PF17848.1 ACL97121.1 - 0.0068 16.4 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Acetyl-coA carboxylase zinc finger domain Trp_syntA PF00290.20 ACL97122.1 - 1.2e-102 342.3 0.4 1.3e-102 342.1 0.4 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain His_biosynth PF00977.21 ACL97122.1 - 2.1e-05 24.1 0.2 3.9e-05 23.2 0.2 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein PcrB PF01884.17 ACL97122.1 - 0.0025 17.3 0.3 0.0042 16.6 0.3 1.4 1 0 0 1 1 1 1 PcrB family PALP PF00291.25 ACL97123.2 - 6.7e-49 166.9 0.4 7.9e-49 166.6 0.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PRAI PF00697.22 ACL97124.1 - 1.1e-55 188.4 0.0 1.3e-55 188.2 0.0 1.0 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Usg PF06233.12 ACL97125.1 - 1.8e-42 143.3 0.1 2e-42 143.2 0.1 1.0 1 0 0 1 1 1 1 Usg-like family PTA_PTB PF01515.19 ACL97128.1 - 1.2e-82 277.8 0.0 1.6e-82 277.4 0.0 1.2 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase malic PF00390.19 ACL97128.1 - 2.4e-26 92.6 0.2 5.2e-24 85.0 0.2 2.4 1 1 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 ACL97128.1 - 1.7e-23 83.3 0.7 7.2e-23 81.2 0.7 2.1 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain ELFV_dehydrog PF00208.21 ACL97128.1 - 0.014 15.1 0.8 0.1 12.3 0.2 2.1 1 1 1 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DapB_C PF05173.14 ACL97129.3 - 9e-42 141.9 0.0 1.7e-41 141.1 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus DapB_N PF01113.20 ACL97129.3 - 4.4e-23 81.8 0.3 9.6e-23 80.6 0.3 1.6 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus CoA_binding_2 PF13380.6 ACL97129.3 - 0.074 13.5 0.3 0.14 12.6 0.3 1.5 1 0 0 1 1 1 0 CoA binding domain DctA-YdbH PF11739.8 ACL97130.1 - 4.3e-23 82.1 0.1 7.1e-20 71.6 0.0 4.1 2 2 0 2 2 2 2 Dicarboxylate transport Lipoprotein_19 PF13617.6 ACL97131.2 - 2.7e-06 27.1 1.0 2.7e-06 27.1 1.0 2.1 1 1 1 2 2 2 1 YnbE-like lipoprotein DUF1318 PF07027.12 ACL97132.1 - 4.2e-25 88.0 3.0 5.3e-25 87.7 3.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1318) DNA_binding_1 PF01035.20 ACL97132.1 - 0.0016 18.6 0.4 0.0034 17.5 0.4 1.5 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain DUF4148 PF13663.6 ACL97133.1 - 0.02 15.1 0.2 0.025 14.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) Gly-zipper_YMGG PF13441.6 ACL97134.1 - 1.4e-09 37.5 31.0 1.4e-09 37.5 31.0 1.6 2 0 0 2 2 2 1 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 ACL97134.1 - 9.6e-08 31.9 51.4 1.3e-06 28.3 29.9 2.2 1 1 1 2 2 2 2 Glycine zipper Gly-zipper_OmpA PF13436.6 ACL97134.1 - 5.5e-06 26.1 35.2 5.5e-06 26.1 35.2 1.8 1 1 1 2 2 2 2 Glycine-zipper domain Rick_17kDa_Anti PF05433.15 ACL97134.1 - 6.4e-05 22.7 51.5 0.00028 20.7 31.6 1.9 1 1 1 2 2 2 2 Glycine zipper 2TM domain OCRE PF17780.1 ACL97134.1 - 0.0029 17.6 7.3 0.0042 17.1 7.3 1.2 1 0 0 1 1 1 1 OCRE domain DUF3482 PF11981.8 ACL97134.1 - 0.082 12.3 14.3 0.085 12.2 14.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) WW PF00397.26 ACL97134.1 - 0.1 12.7 10.4 0.21 11.7 10.4 1.5 1 1 0 1 1 1 0 WW domain DUF533 PF04391.12 ACL97134.1 - 1.9 8.1 5.9 2.4 7.7 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF533) DAGK_cat PF00781.24 ACL97135.2 - 1.4e-09 37.7 0.0 1.9e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 ACL97135.2 - 4.6e-05 22.8 0.0 6.3e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Metallophos PF00149.28 ACL97136.1 - 4e-17 63.4 0.0 5.5e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ACL97136.1 - 3.4e-12 46.9 0.0 8.1e-12 45.6 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Sod_Fe_C PF02777.18 ACL97137.1 - 2.5e-32 111.1 0.3 1.4e-31 108.7 0.0 2.1 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 ACL97137.1 - 2.3e-28 98.5 0.1 4.5e-28 97.5 0.1 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Phage_holin_3_6 PF07332.11 ACL97138.1 - 0.0025 17.9 12.7 0.0025 17.9 12.7 2.0 2 0 0 2 2 2 1 Putative Actinobacterial Holin-X, holin superfamily III DcuC PF03606.15 ACL97138.1 - 0.24 9.8 10.5 0.31 9.5 10.5 1.1 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier DUF3792 PF12670.7 ACL97138.1 - 1.6 8.9 11.2 0.16 12.1 6.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) DUF4407 PF14362.6 ACL97138.1 - 2.2 7.5 9.3 3.7 6.8 9.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Vma12 PF11712.8 ACL97138.1 - 2.9 8.0 5.2 4 7.5 5.2 1.3 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF883 PF05957.13 ACL97138.1 - 4.5 7.9 0.0 4.5 7.9 0.0 3.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) PrgI PF12666.7 ACL97138.1 - 9.7 7.0 7.4 8.7 7.1 4.3 2.1 2 0 0 2 2 2 0 PrgI family protein DUF883 PF05957.13 ACL97139.1 - 1.2e-07 32.2 10.7 2.5e-07 31.2 6.5 1.9 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF883) EcsC PF12787.7 ACL97139.1 - 0.023 14.4 0.8 0.038 13.7 0.8 1.4 1 1 0 1 1 1 0 EcsC protein family Apolipoprotein PF01442.18 ACL97139.1 - 0.027 14.3 4.7 0.036 14.0 4.7 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain LZ_Tnp_IS481 PF13011.6 ACL97139.1 - 0.066 13.8 0.1 0.085 13.4 0.1 1.3 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 SMBP PF16785.5 ACL97139.1 - 0.13 12.5 10.1 0.063 13.5 7.2 1.7 1 1 1 2 2 2 0 Small metal-binding protein Phasin_2 PF09361.10 ACL97139.1 - 0.49 10.7 8.2 0.9 9.8 8.2 1.4 1 1 0 1 1 1 0 Phasin protein ATP-synt_B PF00430.18 ACL97139.1 - 3.5 7.7 13.6 6.4 6.9 13.6 1.4 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) HWE_HK PF07536.14 ACL97140.1 - 8.7e-24 84.0 0.3 1.9e-23 82.9 0.3 1.6 1 0 0 1 1 1 1 HWE histidine kinase PAS_3 PF08447.12 ACL97140.1 - 2.2e-12 47.1 0.0 3.6e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 PAS fold HisKA_2 PF07568.12 ACL97140.1 - 2.1e-06 27.7 0.1 4.2e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase HATPase_c_2 PF13581.6 ACL97140.1 - 3.3e-05 23.8 0.0 0.00011 22.2 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PAS PF00989.25 ACL97140.1 - 6e-05 23.0 0.0 0.00015 21.7 0.0 1.7 1 0 0 1 1 1 1 PAS fold Response_reg PF00072.24 ACL97140.1 - 0.00025 21.2 0.0 0.00085 19.5 0.0 1.9 2 0 0 2 2 2 1 Response regulator receiver domain PAS_4 PF08448.10 ACL97140.1 - 0.00083 19.6 0.6 0.046 14.0 0.0 2.9 3 0 0 3 3 3 1 PAS fold Pribosyltran PF00156.27 ACL97140.1 - 0.085 12.4 0.1 0.21 11.1 0.1 1.6 1 0 0 1 1 1 0 Phosphoribosyl transferase domain DUF3802 PF12290.8 ACL97140.1 - 0.13 12.8 0.1 0.23 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3802) Acetyltransf_1 PF00583.25 ACL97141.1 - 3.8e-14 52.9 0.0 4.4e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ACL97141.1 - 4.9e-06 26.9 0.0 6.7e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ACL97141.1 - 4.5e-05 23.3 0.0 6.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 ACL97141.1 - 7.5e-05 22.8 0.0 0.00011 22.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ACL97141.1 - 0.00012 22.3 0.0 0.00021 21.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ACL97141.1 - 0.00021 21.2 0.0 0.00029 20.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ACL97141.1 - 0.0041 17.8 0.0 0.005 17.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 ACL97141.1 - 0.055 13.1 0.2 0.099 12.3 0.2 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain CoA_transf_3 PF02515.17 ACL97142.2 - 1e-134 449.4 0.0 1.1e-134 449.2 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III DUF4142 PF13628.6 ACL97143.2 - 2.6e-40 137.9 5.5 3.9e-40 137.3 5.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4142) DUF305 PF03713.13 ACL97143.2 - 3.4e-10 40.2 2.1 2.4e-08 34.2 0.7 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF305) LPAM_2 PF13627.6 ACL97143.2 - 0.0014 18.4 1.4 0.0024 17.7 1.4 1.4 1 0 0 1 1 1 1 Prokaryotic lipoprotein-attachment site PC_rep PF01851.22 ACL97143.2 - 0.094 13.2 0.9 0.8 10.3 0.2 2.5 2 0 0 2 2 2 0 Proteasome/cyclosome repeat 4HBT PF03061.22 ACL97144.1 - 3.7e-16 59.3 0.1 5.2e-16 58.8 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 ACL97144.1 - 1.5e-06 28.6 0.2 2e-06 28.2 0.2 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.6 ACL97144.1 - 0.007 16.5 0.0 0.0081 16.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) Peptidase_M1 PF01433.20 ACL97145.1 - 4.6e-11 42.7 0.0 8.4e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ABC2_membrane_2 PF12679.7 ACL97145.1 - 1.3e-08 34.5 35.9 0.00026 20.4 18.5 3.1 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 ACL97145.1 - 2.4e-08 33.5 32.4 6.6e-07 28.8 12.5 2.8 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC2_membrane_4 PF12730.7 ACL97145.1 - 0.00018 21.5 8.9 0.00018 21.5 8.9 3.1 3 1 0 3 3 3 1 ABC-2 family transporter protein ABC2_membrane_5 PF13346.6 ACL97145.1 - 0.11 12.0 26.2 0.23 11.0 7.5 3.3 3 1 0 3 3 3 0 ABC-2 family transporter protein VapB_antitoxin PF09957.9 ACL97145.1 - 0.16 11.9 0.1 6.8 6.7 0.0 2.4 2 0 0 2 2 2 0 Bacterial antitoxin of type II TA system, VapB ABC_tran PF00005.27 ACL97146.1 - 6.1e-30 104.5 0.0 8.6e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ACL97146.1 - 7.8e-13 48.9 0.0 3.7e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ACL97146.1 - 3.7e-05 23.3 0.0 0.027 13.9 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ACL97146.1 - 9.2e-05 22.1 0.0 0.00019 21.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 ACL97146.1 - 0.00038 21.0 0.0 0.00063 20.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 ACL97146.1 - 0.00073 19.3 0.0 0.44 10.2 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 ACL97146.1 - 0.001 19.2 0.0 0.011 15.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ACL97146.1 - 0.0026 17.5 0.0 0.017 14.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ACL97146.1 - 0.0032 17.9 0.0 0.0089 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ACL97146.1 - 0.017 15.4 0.1 0.11 12.8 0.1 2.1 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 ACL97146.1 - 0.027 14.2 0.0 8.3 6.1 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 ACL97146.1 - 0.047 13.6 0.1 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA PF00004.29 ACL97146.1 - 0.048 14.1 0.1 0.38 11.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 ACL97146.1 - 0.098 12.4 0.1 2.2 8.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 ACL97146.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain MukB PF04310.12 ACL97146.1 - 0.13 12.0 0.1 0.38 10.5 0.0 1.7 2 0 0 2 2 2 0 MukB N-terminal NACHT PF05729.12 ACL97146.1 - 0.18 11.7 0.1 0.36 10.7 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_13 PF13166.6 ACL97146.1 - 0.23 10.1 0.0 0.38 9.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain FAA_hydrolase PF01557.18 ACL97147.1 - 1.4e-48 165.5 0.1 1.6e-48 165.3 0.1 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family GST_N_3 PF13417.6 ACL97148.1 - 1.7e-12 47.6 0.0 3.5e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ACL97148.1 - 2.1e-11 44.0 0.0 3.9e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ACL97148.1 - 2.6e-10 40.5 0.0 4.2e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ACL97148.1 - 0.00016 21.7 0.9 0.00028 20.9 0.4 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ACL97148.1 - 0.00031 20.9 0.0 0.0005 20.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ACL97148.1 - 0.007 16.6 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain LssY_C PF14067.6 ACL97148.1 - 0.072 12.6 0.0 0.09 12.3 0.0 1.1 1 0 0 1 1 1 0 LssY C-terminus Pro_CA PF00484.19 ACL97149.1 - 1.5e-51 174.8 0.0 1.9e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Tim17 PF02466.19 ACL97149.1 - 0.029 14.7 0.0 0.043 14.2 0.0 1.2 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Transgly PF00912.22 ACL97150.1 - 1.4e-43 148.4 0.0 2.5e-43 147.6 0.0 1.4 1 0 0 1 1 1 1 Transglycosylase BiPBP_C PF06832.12 ACL97150.1 - 3.2e-16 59.1 0.1 3.2e-16 59.1 0.1 3.2 4 1 1 5 5 5 1 Penicillin-Binding Protein C-terminus Family Transpeptidase PF00905.22 ACL97150.1 - 2.4e-14 53.2 0.0 7e-14 51.7 0.0 1.6 1 1 0 1 1 1 1 Penicillin binding protein transpeptidase domain BAT PF15915.5 ACL97150.1 - 0.019 14.9 0.1 1.5 8.6 0.1 3.0 1 1 2 3 3 3 0 GAF and HTH_10 associated domain bMG5 PF17972.1 ACL97151.1 - 5e-26 91.5 0.1 1.6e-25 89.9 0.1 2.0 1 0 0 1 1 1 1 Bacterial Alpha-2-macroglobulin MG5 domain bMG6 PF17962.1 ACL97151.1 - 7.1e-25 87.4 1.8 7.1e-25 87.4 1.8 2.9 3 0 0 3 3 3 1 Bacterial macroglobulin domain 6 bMG3 PF11974.8 ACL97151.1 - 9.8e-25 86.6 3.5 2.4e-24 85.3 0.3 3.2 3 0 0 3 3 3 1 Bacterial alpha-2-macroglobulin MG3 domain MG2 PF01835.19 ACL97151.1 - 2e-21 76.2 0.0 7.9e-21 74.3 0.0 2.1 1 0 0 1 1 1 1 MG2 domain bMG10 PF17973.1 ACL97151.1 - 1.5e-20 73.7 0.0 5.8e-20 71.8 0.0 2.1 1 0 0 1 1 1 1 Bacterial Alpha-2-macroglobulin MG10 domain A2M_BRD PF07703.14 ACL97151.1 - 2.3e-13 50.7 0.0 1.3e-11 45.0 0.0 2.7 2 1 0 2 2 2 1 Alpha-2-macroglobulin bait region domain A2M PF00207.22 ACL97151.1 - 7.5e-10 38.5 0.0 2.2e-09 37.0 0.0 1.8 1 0 0 1 1 1 1 Alpha-2-macroglobulin family TED_complement PF07678.14 ACL97151.1 - 0.00037 19.6 0.0 0.0011 18.1 0.0 1.6 2 0 0 2 2 2 1 A-macroglobulin TED domain CarboxypepD_reg PF13620.6 ACL97151.1 - 0.026 14.8 0.2 0.5 10.7 0.0 3.5 3 1 0 3 3 3 0 Carboxypeptidase regulatory-like domain DUF4232 PF14016.6 ACL97151.1 - 6.5 6.9 7.7 1.3 9.2 0.1 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF4232) Pro_CA PF00484.19 ACL97152.2 - 4.4e-36 124.5 0.3 6.7e-36 123.9 0.3 1.3 1 0 0 1 1 1 1 Carbonic anhydrase AsnC_trans_reg PF01037.21 ACL97153.1 - 2.1e-23 82.1 0.4 3.5e-23 81.3 0.4 1.4 1 0 0 1 1 1 1 Lrp/AsnC ligand binding domain HTH_AsnC-type PF13404.6 ACL97153.1 - 4.4e-17 61.6 0.9 4.4e-17 61.6 0.9 1.8 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 ACL97153.1 - 4.8e-14 51.6 0.1 9.1e-14 50.8 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 ACL97153.1 - 5.9e-06 26.1 0.1 1.1e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 MarR family HTH_20 PF12840.7 ACL97153.1 - 6.9e-05 22.8 0.3 0.00015 21.8 0.3 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 ACL97153.1 - 0.013 15.3 1.9 0.033 14.1 1.9 1.6 1 0 0 1 1 1 0 MarR family HTH_11 PF08279.12 ACL97153.1 - 0.031 14.2 0.4 0.21 11.6 0.1 2.2 2 0 0 2 2 2 0 HTH domain HTH_34 PF13601.6 ACL97153.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_27 PF13463.6 ACL97153.1 - 0.14 12.7 0.7 1.2 9.7 0.1 2.1 2 0 0 2 2 2 0 Winged helix DNA-binding domain AlaDh_PNT_C PF01262.21 ACL97154.1 - 1.7e-77 259.5 0.3 2.2e-77 259.2 0.3 1.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 ACL97154.1 - 2.1e-44 151.1 0.0 5.1e-44 149.9 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain 2-Hacid_dh_C PF02826.19 ACL97154.1 - 1.2e-07 31.2 0.0 2.8e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 ACL97154.1 - 2.2e-06 27.8 0.0 4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 ACL97154.1 - 5.3e-05 22.6 0.7 0.00011 21.5 0.4 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ACL97154.1 - 8.8e-05 23.0 0.1 0.00017 22.0 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 ACL97154.1 - 0.00012 22.3 0.6 0.00028 21.1 0.2 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase DAO PF01266.24 ACL97154.1 - 0.0013 18.4 0.8 0.0054 16.3 0.6 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase F420_oxidored PF03807.17 ACL97154.1 - 0.0019 18.8 1.0 0.003 18.1 0.2 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 ACL97154.1 - 0.0065 16.4 1.1 0.014 15.3 1.0 1.6 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 ACL97154.1 - 0.04 14.4 0.1 0.074 13.5 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding GIDA PF01134.22 ACL97154.1 - 0.061 12.4 0.3 0.082 12.0 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A TrkA_N PF02254.18 ACL97154.1 - 0.16 12.2 0.5 2.4 8.5 0.2 2.4 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_8 PF13450.6 ACL97154.1 - 0.42 10.9 3.0 1.9 8.8 1.6 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 ACL97154.1 - 1.1 8.5 5.6 1.6 8.0 5.6 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase CTP_transf_3 PF02348.19 ACL97155.1 - 3e-19 69.8 0.0 3.6e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 ACL97155.1 - 2.6e-10 40.9 3.2 2.9e-10 40.7 1.4 1.7 1 1 1 2 2 2 1 MobA-like NTP transferase domain DUF2064 PF09837.9 ACL97155.1 - 0.063 13.1 0.5 0.15 11.9 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2064) Aldo_ket_red PF00248.21 ACL97156.1 - 1.3e-13 50.8 0.0 1.9e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family B-block_TFIIIC PF04182.12 ACL97156.1 - 0.15 12.2 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC XdhC_C PF13478.6 ACL97157.1 - 4e-26 92.0 0.0 8.1e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 XdhC Rossmann domain XdhC_CoxI PF02625.16 ACL97157.1 - 1.6e-15 57.1 4.4 1.6e-15 57.0 1.8 2.4 2 1 0 2 2 2 1 XdhC and CoxI family DUF362 PF04015.12 ACL97157.1 - 0.071 13.3 0.0 0.095 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF362) Creatininase PF02633.14 ACL97158.1 - 2.4e-59 200.7 0.0 2.7e-59 200.6 0.0 1.0 1 0 0 1 1 1 1 Creatinine amidohydrolase HTH_8 PF02954.19 ACL97159.1 - 2.9e-12 46.2 1.4 6.8e-12 45.0 1.4 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family GAF PF01590.26 ACL97159.1 - 1.3e-09 38.7 0.3 3.4e-09 37.4 0.1 1.8 2 0 0 2 2 2 1 GAF domain HTH_30 PF13556.6 ACL97159.1 - 0.0023 17.7 0.3 0.0058 16.4 0.3 1.7 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_29 PF13551.6 ACL97159.1 - 0.0031 17.5 0.8 0.021 14.8 0.1 2.6 1 1 1 2 2 2 1 Winged helix-turn helix HTH_Tnp_ISL3 PF13542.6 ACL97159.1 - 0.011 15.2 0.4 0.049 13.0 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 ACL97159.1 - 0.028 14.2 0.2 0.12 12.3 0.1 2.1 2 0 0 2 2 2 0 Homeodomain-like domain HTH_28 PF13518.6 ACL97159.1 - 0.029 14.5 0.3 0.071 13.2 0.3 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain PAS_4 PF08448.10 ACL97159.1 - 0.055 13.7 0.4 5.7 7.2 0.0 2.7 2 0 0 2 2 2 0 PAS fold HTH_1 PF00126.27 ACL97159.1 - 0.057 13.4 0.5 0.057 13.4 0.5 2.2 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family UBA PF00627.31 ACL97159.1 - 0.46 10.4 1.7 0.78 9.7 0.5 2.1 2 0 0 2 2 2 0 UBA/TS-N domain Aldedh PF00171.22 ACL97160.1 - 8.1e-165 548.8 0.0 9.1e-165 548.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OmdA PF13376.6 ACL97160.1 - 0.059 13.4 0.3 0.13 12.3 0.3 1.5 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated AMP-binding PF00501.28 ACL97161.1 - 6e-93 311.7 0.0 7.1e-93 311.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ACL97161.1 - 1.8e-24 86.5 0.1 5.1e-24 85.1 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 ACL97161.1 - 1e-15 57.4 0.2 2.7e-15 56.0 0.0 1.8 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Polyketide_cyc PF03364.20 ACL97162.1 - 5.9e-18 65.3 0.0 8.1e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 ACL97162.1 - 3.6e-14 53.2 0.1 5.2e-14 52.7 0.1 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF393 PF04134.12 ACL97163.1 - 1.3e-29 103.8 0.1 1.5e-29 103.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF393 Peptidase_M16_C PF05193.21 ACL97164.1 - 1e-64 217.9 0.0 2e-31 109.4 0.0 4.3 4 0 0 4 4 4 3 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 ACL97164.1 - 4.3e-33 114.4 0.0 3.2e-17 62.9 0.0 2.4 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) MscL PF01741.18 ACL97165.1 - 8.7e-45 151.9 0.2 1e-44 151.7 0.2 1.0 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL Bac_DNA_binding PF00216.21 ACL97166.1 - 1.2e-29 102.3 0.0 1.3e-29 102.2 0.0 1.0 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 ACL97166.1 - 3e-05 24.1 0.0 3.3e-05 24.0 0.0 1.0 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-DNA_bdg PF14848.6 ACL97166.1 - 0.0084 16.1 0.0 0.011 15.7 0.0 1.4 1 1 0 1 1 1 1 DNA-binding domain TetR_C_30 PF17939.1 ACL97166.1 - 0.1 12.8 0.0 0.17 12.1 0.0 1.4 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain S1 PF00575.23 ACL97167.1 - 3.8e-104 341.2 26.6 7.7e-22 77.4 0.2 6.1 6 0 0 6 6 6 6 S1 RNA binding domain PCB_OB PF17092.5 ACL97167.1 - 1.7e-08 35.2 6.1 0.0027 18.5 0.2 5.6 2 1 4 6 6 6 2 Penicillin-binding protein OB-like domain RNase_II_C_S1 PF18614.1 ACL97167.1 - 3.7e-07 30.0 11.0 0.77 9.8 0.1 6.7 6 0 0 6 6 6 3 RNase II-type exonuclease C-terminal S1 domain S1_2 PF13509.6 ACL97167.1 - 1.6e-05 24.9 9.8 1.8 8.7 0.1 5.9 7 1 0 7 7 7 2 S1 domain PLD_C PF12357.8 ACL97167.1 - 0.014 15.2 0.1 6.3 6.8 0.0 3.2 4 0 0 4 4 4 0 Phospholipase D C terminal TRAM_2 PF18693.1 ACL97167.1 - 0.057 13.6 2.6 36 4.6 0.1 4.4 5 0 0 5 5 5 0 TRAM domain EXOSC1 PF10447.9 ACL97167.1 - 0.13 12.9 10.4 0.35 11.5 0.2 4.2 3 1 1 4 4 4 0 Exosome component EXOSC1/CSL4 HupF_HypC PF01455.18 ACL97167.1 - 0.17 12.0 2.1 21 5.3 0.0 4.0 4 0 0 4 4 4 0 HupF/HypC family CsrA PF02599.16 ACL97167.1 - 2.1 8.4 4.5 13 5.8 0.0 3.9 5 0 0 5 5 5 0 Global regulator protein family RuvA_N PF01330.21 ACL97167.1 - 3.2 7.9 4.4 8.5 6.6 0.1 3.2 3 0 0 3 3 3 0 RuvA N terminal domain Cytidylate_kin PF02224.18 ACL97168.1 - 2.7e-52 177.6 0.4 8.6e-52 175.9 0.4 1.6 1 1 0 1 1 1 1 Cytidylate kinase AAA_17 PF13207.6 ACL97168.1 - 0.00013 22.4 0.1 0.00059 20.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ACL97168.1 - 0.00058 20.4 0.0 0.0033 18.0 0.0 2.2 1 1 1 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.6 ACL97168.1 - 0.00086 19.5 1.7 0.018 15.2 1.7 2.9 1 1 0 1 1 1 1 Cytidylate kinase-like family CoaE PF01121.20 ACL97168.1 - 0.013 15.1 0.1 0.028 14.1 0.1 1.6 1 1 0 1 1 1 0 Dephospho-CoA kinase ADK PF00406.22 ACL97168.1 - 0.026 14.6 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 Adenylate kinase AAA_33 PF13671.6 ACL97168.1 - 0.045 13.9 0.1 0.19 11.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain EPSP_synthase PF00275.20 ACL97169.1 - 6.2e-103 344.7 0.1 7e-103 344.5 0.1 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) FYDLN_acid PF09538.10 ACL97170.2 - 1.1e-23 84.0 30.0 7.8e-22 78.0 30.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (FYDLN_acid) TF_Zn_Ribbon PF08271.12 ACL97170.2 - 6.6e-05 22.3 0.7 6.6e-05 22.3 0.7 2.6 3 0 0 3 3 3 1 TFIIB zinc-binding DZR PF12773.7 ACL97170.2 - 0.00074 19.5 1.0 0.0013 18.7 1.0 1.3 1 0 0 1 1 1 1 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 ACL97170.2 - 0.0013 18.6 0.3 0.0022 17.9 0.3 1.3 1 0 0 1 1 1 1 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.6 ACL97170.2 - 0.0048 16.3 3.0 0.75 9.3 0.2 2.5 2 0 0 2 2 2 2 zinc-ribbon domain FYVE PF01363.21 ACL97170.2 - 0.013 15.6 0.0 0.017 15.3 0.0 1.2 1 0 0 1 1 1 0 FYVE zinc finger zinc_ribbon_2 PF13240.6 ACL97170.2 - 0.023 14.4 1.6 1.2 9.0 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 ACL97170.2 - 0.029 14.3 3.3 0.18 11.8 3.3 2.0 1 1 0 1 1 1 0 PhnA Zinc-Ribbon Zn_Tnp_IS1595 PF12760.7 ACL97170.2 - 0.03 14.3 5.0 2 8.5 0.3 2.4 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_4 PF13717.6 ACL97170.2 - 0.032 14.1 3.6 3.5 7.6 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 ACL97170.2 - 0.047 13.7 0.5 0.081 12.9 0.5 1.4 1 0 0 1 1 1 0 zinc-ribbons zf-NADH-PPase PF09297.11 ACL97170.2 - 0.067 12.9 0.8 8.4 6.2 0.1 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DUF2318 PF10080.9 ACL97170.2 - 0.071 13.2 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) zf-ISL3 PF14690.6 ACL97170.2 - 0.075 13.7 1.3 6.6 7.5 0.2 2.2 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf_UBZ PF18439.1 ACL97170.2 - 0.083 12.5 2.1 1.1 8.9 0.2 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger TackOD1 PF18551.1 ACL97170.2 - 0.089 12.4 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 Zn-ribbon_8 PF09723.10 ACL97170.2 - 0.099 12.8 4.2 0.47 10.6 4.1 2.0 1 1 2 3 3 3 0 Zinc ribbon domain HypA PF01155.19 ACL97170.2 - 0.14 12.2 0.4 0.21 11.6 0.4 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Rad50_zn_hook PF04423.14 ACL97170.2 - 0.27 11.1 4.6 1.3 8.9 0.8 2.5 1 1 1 2 2 2 0 Rad50 zinc hook motif Prok-RING_1 PF14446.6 ACL97170.2 - 0.29 11.1 2.1 0.9 9.5 2.1 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-C2HC_2 PF13913.6 ACL97170.2 - 0.32 10.9 0.0 0.32 10.9 0.0 2.1 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zinc_ribbon_9 PF14369.6 ACL97170.2 - 0.38 11.1 8.2 3.6 7.9 0.5 3.0 2 1 1 3 3 3 0 zinc-ribbon DUF1610 PF07754.11 ACL97170.2 - 0.51 10.4 6.8 4.6 7.3 1.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) zf-RING_4 PF14570.6 ACL97170.2 - 1 9.2 5.3 6 6.7 0.5 2.5 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Zn_ribbon_SprT PF17283.2 ACL97170.2 - 1.1 9.3 3.3 8.9 6.3 0.2 2.1 1 1 1 2 2 2 0 SprT-like zinc ribbon domain zf_C2H2_10 PF18414.1 ACL97170.2 - 2.5 7.7 8.2 1.8 8.2 0.3 2.9 3 1 0 3 3 2 0 C2H2 type zinc-finger HSP20 PF00011.21 ACL97171.1 - 7.2e-15 55.0 0.0 9.2e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ACL97171.1 - 0.009 15.6 0.1 0.039 13.5 0.1 1.9 1 1 0 1 1 1 1 HSP20-like domain found in ArsA DUF1150 PF06620.11 ACL97172.1 - 2.3e-27 94.9 0.2 2.6e-27 94.7 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1150) DUF3014 PF11219.8 ACL97172.1 - 0.032 14.5 0.0 0.042 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3014) Rnk_N PF14760.6 ACL97172.1 - 0.086 13.3 0.4 0.086 13.3 0.4 1.7 2 0 0 2 2 2 0 Rnk N-terminus DDE_Tnp_1_2 PF13586.6 ACL97173.1 - 1.8e-17 63.5 0.2 2.3e-17 63.2 0.2 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1 PF01609.21 ACL97173.1 - 4.4e-11 42.8 0.4 5.9e-10 39.2 0.4 1.9 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_4 PF13359.6 ACL97173.1 - 2e-05 24.3 0.0 2.3e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_3 PF13612.6 ACL97173.1 - 4.2e-05 23.6 0.0 5.3e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain DDE_5 PF13546.6 ACL97173.1 - 0.007 15.7 0.1 0.0081 15.5 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease BT1 PF03092.16 ACL97173.1 - 0.047 11.9 0.0 0.05 11.8 0.0 1.0 1 0 0 1 1 1 0 BT1 family DUF4096 PF13340.6 ACL97174.1 - 1.4e-25 89.3 3.5 1.9e-25 88.9 3.5 1.2 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) PTS_EIIA_2 PF00359.22 ACL97175.3 - 5.2e-29 101.0 0.0 5.9e-29 100.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Ribosom_S30AE_C PF16321.5 ACL97176.1 - 1.7e-16 59.6 0.0 3.2e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Sigma 54 modulation/S30EA ribosomal protein C terminus Ribosomal_S30AE PF02482.19 ACL97176.1 - 1.9e-14 54.2 0.0 3e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein ExoD PF06055.12 ACL97177.1 - 3.1e-50 170.1 12.9 3.9e-50 169.7 12.9 1.0 1 0 0 1 1 1 1 Exopolysaccharide synthesis, ExoD Sigma54_DBD PF04552.13 ACL97178.1 - 7.7e-70 233.7 0.3 1.1e-69 233.2 0.3 1.2 1 0 0 1 1 1 1 Sigma-54, DNA binding domain Sigma54_CBD PF04963.13 ACL97178.1 - 5.4e-50 169.7 0.0 9.3e-50 169.0 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 factor, core binding domain Sigma54_AID PF00309.20 ACL97178.1 - 7.1e-17 61.0 5.3 1.5e-16 59.9 5.3 1.6 1 0 0 1 1 1 1 Sigma-54 factor, Activator interacting domain (AID) HTH_3 PF01381.22 ACL97178.1 - 0.013 15.5 0.2 0.49 10.5 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix HTH_IclR PF09339.10 ACL97178.1 - 0.026 14.3 0.1 0.15 11.9 0.0 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_Crp_2 PF13545.6 ACL97178.1 - 0.11 12.5 0.0 2.4 8.2 0.0 2.6 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_23 PF13384.6 ACL97178.1 - 0.12 12.2 0.2 2.5 8.0 0.0 2.9 3 0 0 3 3 3 0 Homeodomain-like domain HTH_AraC PF00165.23 ACL97178.1 - 0.16 12.1 0.0 0.41 10.8 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family ABC_tran PF00005.27 ACL97179.1 - 6.9e-34 117.3 0.0 9.9e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ACL97179.1 - 7.7e-08 32.5 0.2 0.00053 19.9 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system BCA_ABC_TP_C PF12399.8 ACL97179.1 - 2.8e-07 30.3 0.1 7.6e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 Branched-chain amino acid ATP-binding cassette transporter SMC_N PF02463.19 ACL97179.1 - 0.076 12.4 0.0 7.1 6.0 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 ACL97179.1 - 0.11 12.7 0.2 0.7 10.2 0.2 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 ACL97179.1 - 0.14 12.6 0.0 0.24 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain OstA PF03968.14 ACL97180.1 - 4.2e-24 84.9 2.4 6.1e-24 84.4 2.4 1.2 1 0 0 1 1 1 1 OstA-like protein LptC PF06835.13 ACL97180.1 - 0.0084 15.7 2.9 0.2 11.2 1.4 2.4 1 1 1 2 2 2 2 Lipopolysaccharide-assembly, LptC-related LPAM_1 PF08139.12 ACL97180.1 - 4.4 8.0 5.6 0.63 10.6 1.2 1.9 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site LptC PF06835.13 ACL97181.3 - 1.4e-08 34.5 0.0 5.3e-08 32.7 0.0 2.0 2 1 0 2 2 2 1 Lipopolysaccharide-assembly, LptC-related DNA_pol_A_exo1 PF01612.20 ACL97182.1 - 1.3e-29 103.2 0.0 1.6e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease NAD_binding_10 PF13460.6 ACL97183.1 - 1.6e-20 73.8 4.4 2.8e-20 73.0 4.4 1.4 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ACL97183.1 - 2e-18 66.8 0.0 2.7e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 ACL97183.1 - 1.6e-17 63.4 0.0 1.2e-12 47.5 0.2 2.1 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ACL97183.1 - 2.7e-16 59.8 0.1 1.6e-15 57.3 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ACL97183.1 - 1.4e-14 53.9 0.1 6.4e-13 48.4 0.1 2.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 ACL97183.1 - 3.6e-07 29.6 0.3 0.0091 15.2 0.0 3.1 2 1 1 3 3 3 3 Male sterility protein Glyco_trans_4_4 PF13579.6 ACL97183.1 - 0.00014 22.4 3.8 0.00015 22.2 2.3 1.7 1 1 1 2 2 2 1 Glycosyl transferase 4-like domain GDP_Man_Dehyd PF16363.5 ACL97183.1 - 0.0003 20.3 0.1 0.00049 19.6 0.1 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 ACL97183.1 - 0.002 17.6 1.3 0.007 15.8 1.3 1.8 1 1 0 1 1 1 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 ACL97183.1 - 0.0023 18.2 0.5 0.0081 16.4 0.5 1.9 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 ACL97183.1 - 0.017 15.0 1.4 0.067 13.1 1.3 1.9 1 1 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 ACL97183.1 - 0.025 13.7 0.6 0.051 12.7 0.6 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Glyco_transf_4 PF13439.6 ACL97183.1 - 0.038 14.0 0.8 0.44 10.5 0.1 2.2 2 1 0 2 2 2 0 Glycosyltransferase Family 4 adh_short_C2 PF13561.6 ACL97183.1 - 0.043 13.4 2.3 0.24 10.9 0.1 2.2 1 1 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase BacA PF02673.18 ACL97184.1 - 7.4e-75 252.0 11.0 8.5e-75 251.8 11.0 1.0 1 0 0 1 1 1 1 Bacitracin resistance protein BacA ThrE PF06738.12 ACL97184.1 - 0.00036 20.0 1.9 0.00036 20.0 1.9 2.1 1 1 1 2 2 2 2 Putative threonine/serine exporter Fer4_20 PF14691.6 ACL97186.1 - 2.9e-37 126.9 0.3 4.4e-37 126.3 0.3 1.2 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.14 ACL97186.1 - 2.7e-29 102.3 1.2 3.7e-29 101.9 1.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ACL97186.1 - 1.3e-11 44.9 0.8 5.2e-05 23.7 0.1 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ACL97186.1 - 1.4e-11 44.4 0.9 1.9e-10 40.8 0.3 2.7 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ACL97186.1 - 7.4e-10 38.6 1.6 0.0017 17.7 0.2 3.2 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 ACL97186.1 - 1.4e-07 31.9 0.8 0.012 16.1 0.1 2.8 2 1 0 2 2 2 2 Putative NAD(P)-binding Amino_oxidase PF01593.24 ACL97186.1 - 2.3e-06 27.2 1.1 4e-05 23.1 0.2 2.6 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 ACL97186.1 - 4.8e-06 26.0 1.0 8.4e-06 25.3 0.1 1.8 3 0 0 3 3 1 1 FAD binding domain HI0933_like PF03486.14 ACL97186.1 - 1.4e-05 24.0 1.1 8.4e-05 21.4 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein 2-Hacid_dh_C PF02826.19 ACL97186.1 - 1.6e-05 24.3 0.1 7.1e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 ACL97186.1 - 5.9e-05 22.3 3.9 0.0013 17.9 0.5 3.0 3 0 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.21 ACL97186.1 - 0.0002 20.7 1.4 0.034 13.4 0.2 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 ACL97186.1 - 0.00037 20.6 0.1 0.48 10.5 0.0 2.6 2 1 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 ACL97186.1 - 0.00059 20.0 0.2 0.027 14.7 0.0 3.1 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase Thi4 PF01946.17 ACL97186.1 - 0.00088 18.6 3.1 0.0062 15.8 0.1 2.8 3 0 0 3 3 3 1 Thi4 family DAO PF01266.24 ACL97186.1 - 0.0021 17.7 7.7 0.0026 17.4 0.7 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase ApbA PF02558.16 ACL97186.1 - 0.0025 17.5 0.1 0.067 12.8 0.1 2.4 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 ACL97186.1 - 0.0041 16.5 0.3 0.0041 16.5 0.3 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 ACL97186.1 - 0.011 15.7 0.1 0.039 13.8 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K_oxygenase PF13434.6 ACL97186.1 - 0.011 14.9 0.0 0.047 12.8 0.0 1.8 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) IlvN PF07991.12 ACL97186.1 - 0.011 15.3 0.1 0.038 13.6 0.1 1.9 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Glu_dehyd_C PF16912.5 ACL97186.1 - 0.013 15.0 0.1 0.063 12.8 0.0 2.1 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus XdhC_C PF13478.6 ACL97186.1 - 0.014 15.9 0.2 0.6 10.6 0.0 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain Transketolase_C PF02780.20 ACL97186.1 - 0.018 14.9 0.3 4.3 7.2 0.0 2.8 3 0 0 3 3 2 0 Transketolase, C-terminal domain NAD_binding_9 PF13454.6 ACL97186.1 - 0.018 15.0 0.2 0.044 13.8 0.2 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.22 ACL97186.1 - 0.03 13.4 2.0 0.11 11.6 0.4 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A F420_oxidored PF03807.17 ACL97186.1 - 0.036 14.6 0.1 2.4 8.8 0.0 3.2 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent ELFV_dehydrog PF00208.21 ACL97186.1 - 0.096 12.4 0.1 5.6 6.6 0.0 2.2 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Lycopene_cycl PF05834.12 ACL97186.1 - 0.27 10.2 1.2 0.29 10.1 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Fer4_10 PF13237.6 ACL97186.1 - 0.88 9.7 6.4 1.8 8.7 6.4 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Tnp_zf-ribbon_2 PF13842.6 ACL97186.1 - 1.1 10.1 7.2 0.3 11.9 3.9 1.8 2 0 0 2 2 1 0 DDE_Tnp_1-like zinc-ribbon Fer4_8 PF13183.6 ACL97186.1 - 8.1 7.0 8.3 32 5.1 8.3 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain GATase_2 PF00310.21 ACL97187.1 - 1.9e-150 501.3 0.0 2.4e-150 500.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 ACL97187.1 - 5.1e-150 499.7 0.3 3.6e-148 493.6 0.0 2.1 2 0 0 2 2 2 2 Conserved region in glutamate synthase Glu_syn_central PF04898.14 ACL97187.1 - 2.8e-96 322.3 0.0 4.1e-96 321.7 0.0 1.2 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.19 ACL97187.1 - 1.3e-72 243.4 3.4 2.6e-72 242.4 3.4 1.5 1 0 0 1 1 1 1 GXGXG motif FMN_dh PF01070.18 ACL97187.1 - 0.0026 16.9 0.3 0.0064 15.6 0.3 1.6 1 0 0 1 1 1 1 FMN-dependent dehydrogenase GATase_6 PF13522.6 ACL97187.1 - 0.077 13.2 0.0 0.56 10.4 0.0 2.2 2 0 0 2 2 2 0 Glutamine amidotransferase domain GATase_7 PF13537.6 ACL97187.1 - 0.12 12.3 0.0 0.36 10.7 0.0 1.8 1 0 0 1 1 1 0 Glutamine amidotransferase domain NMO PF03060.15 ACL97187.1 - 0.37 10.1 4.3 0.78 9.1 4.3 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase 4HBT PF03061.22 ACL97188.2 - 4.6e-11 42.9 0.0 7e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 ACL97188.2 - 1.2e-10 42.0 0.1 1.5e-10 41.8 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily MtrD PF04207.12 ACL97188.2 - 0.043 13.5 0.4 0.063 13.0 0.4 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit D DUF4442 PF14539.6 ACL97188.2 - 0.19 11.9 0.0 0.21 11.7 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4442) Phage_holin_3_6 PF07332.11 ACL97189.1 - 0.026 14.5 6.9 0.052 13.6 6.9 1.5 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DNA_ligase_A_M PF01068.21 ACL97190.1 - 1.6e-23 83.4 0.0 2.3e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 ACL97190.1 - 1e-10 42.1 0.1 2.4e-10 40.9 0.1 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_A_N PF04675.14 ACL97190.1 - 9.2e-07 29.3 0.0 1.9e-06 28.3 0.0 1.5 1 1 0 1 1 1 1 DNA ligase N terminus DegT_DnrJ_EryC1 PF01041.17 ACL97191.1 - 4.9e-96 322.2 0.0 5.5e-96 322.0 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 ACL97191.1 - 6.1e-06 25.6 0.0 8.4e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ACL97191.1 - 0.0089 15.3 0.0 0.013 14.8 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase SHMT PF00464.19 ACL97191.1 - 0.01 14.4 0.0 0.016 13.8 0.0 1.2 1 0 0 1 1 1 0 Serine hydroxymethyltransferase MS_channel PF00924.18 ACL97192.1 - 1.5e-44 152.0 0.1 2.1e-44 151.6 0.1 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel TM_helix PF05552.12 ACL97192.1 - 1.1e-05 25.3 0.9 3.5e-05 23.7 0.9 1.8 1 0 0 1 1 1 1 Conserved TM helix Fibrillarin PF01269.17 ACL97192.1 - 0.13 11.4 0.0 0.27 10.3 0.0 1.5 1 0 0 1 1 1 0 Fibrillarin AAA_28 PF13521.6 ACL97193.3 - 0.041 14.1 0.0 0.098 12.9 0.0 1.6 1 1 1 2 2 2 0 AAA domain Psb28 PF03912.14 ACL97193.3 - 0.076 13.3 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Psb28 protein TAL_FSA PF00923.19 ACL97194.1 - 3e-59 200.7 2.1 2.3e-57 194.6 2.1 2.1 1 1 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase ALAD PF00490.21 ACL97194.1 - 0.06 12.5 0.0 0.16 11.2 0.0 1.6 1 1 0 1 1 1 0 Delta-aminolevulinic acid dehydratase RmlD_sub_bind PF04321.17 ACL97195.1 - 1.1e-100 336.5 0.2 1.2e-100 336.3 0.2 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 ACL97195.1 - 2.5e-16 59.9 0.0 3.2e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ACL97195.1 - 3.4e-12 46.4 0.1 7.7e-12 45.2 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ACL97195.1 - 7.9e-09 35.1 0.0 8.7e-08 31.6 0.1 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 ACL97195.1 - 5.1e-07 29.1 0.0 1e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein Lipase_GDSL_2 PF13472.6 ACL97195.1 - 0.47 10.8 3.0 1.6 9.1 1.0 2.2 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Hydrolase_like PF13242.6 ACL97196.2 - 1.6e-09 37.7 0.1 4.1e-09 36.4 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.6 ACL97196.2 - 1.1e-08 35.4 0.0 5.2e-07 29.9 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ACL97196.2 - 7.7e-05 23.1 0.8 0.0003 21.2 0.2 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 ACL97196.2 - 0.00015 21.8 0.0 0.00023 21.2 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase PNK3P PF08645.11 ACL97196.2 - 0.0069 16.1 0.0 0.0087 15.8 0.0 1.1 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase PGP_phosphatase PF09419.10 ACL97196.2 - 0.059 13.0 0.0 2.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase GlcNAc_2-epim PF07221.11 ACL97197.3 - 1.8e-105 353.0 0.6 2.2e-105 352.7 0.6 1.1 1 0 0 1 1 1 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) NTP_transferase PF00483.23 ACL97198.1 - 3e-51 174.4 0.0 4.1e-51 174.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 ACL97198.1 - 2e-10 41.3 3.2 2.6e-10 40.9 1.1 2.1 2 0 0 2 2 2 1 MobA-like NTP transferase domain MannoseP_isomer PF01050.18 ACL97198.1 - 2.5e-07 30.7 0.0 5e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase NAD_synthase PF02540.17 ACL97199.1 - 1.6e-22 79.8 0.0 2.5e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.22 ACL97199.1 - 3.2e-20 72.6 0.1 4.6e-20 72.0 0.1 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Transketolase_N PF00456.21 ACL97200.3 - 1.3e-123 412.2 0.6 1.9e-123 411.7 0.6 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 ACL97200.3 - 3.5e-47 160.4 0.3 3.5e-47 160.4 0.3 2.0 3 0 0 3 3 3 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ACL97200.3 - 7.8e-10 38.7 0.0 1.8e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.21 ACL97200.3 - 1.2e-07 31.7 2.8 1.3e-06 28.2 1.1 3.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 ACL97200.3 - 2.2e-07 30.4 0.0 7.7e-06 25.3 0.0 2.2 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 ACL97200.3 - 0.0056 15.7 0.1 0.011 14.8 0.1 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component YGGT PF02325.17 ACL97201.2 - 1.2e-18 67.3 6.6 2e-18 66.5 6.6 1.3 1 0 0 1 1 1 1 YGGT family DUF2207 PF09972.9 ACL97201.2 - 0.13 11.0 1.7 0.14 10.9 1.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4191 PF13829.6 ACL97201.2 - 6.9 5.9 7.3 0.54 9.5 2.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DUF167 PF02594.16 ACL97202.1 - 1.1e-23 83.1 0.0 1.2e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 HATPase_c PF02518.26 ACL97203.1 - 8e-27 94.0 0.0 1.3e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ACL97203.1 - 1.7e-25 89.4 0.0 3e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ACL97203.1 - 8.5e-14 51.4 0.6 3.2e-13 49.5 0.1 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain DUF4203 PF13886.6 ACL97203.1 - 0.011 15.4 3.9 0.016 14.9 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) HATPase_c_2 PF13581.6 ACL97203.1 - 0.048 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Vsr PF03852.15 ACL97204.1 - 6.3e-40 134.9 0.1 1.2e-39 134.0 0.1 1.4 1 0 0 1 1 1 1 DNA mismatch endonuclease Vsr ABC1 PF03109.16 ACL97204.1 - 0.018 15.2 0.0 0.028 14.6 0.0 1.2 1 0 0 1 1 1 0 ABC1 family PALP PF00291.25 ACL97205.1 - 3.6e-71 240.0 2.1 4e-71 239.8 2.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DFP PF04127.15 ACL97205.1 - 0.078 12.8 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein DNA_methylase PF00145.17 ACL97206.2 - 2.3e-42 145.5 0.0 6.6e-41 140.8 0.0 2.0 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase Beta-lactamase PF00144.24 ACL97208.3 - 1.8e-73 247.6 7.2 2.5e-73 247.2 7.2 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF5545 PF17699.1 ACL97208.3 - 0.37 10.6 2.9 2.7 7.8 1.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5545) GDP_Man_Dehyd PF16363.5 ACL97209.1 - 1.2e-90 304.3 0.0 1.4e-90 304.1 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ACL97209.1 - 2.1e-65 220.6 0.0 2.6e-65 220.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ACL97209.1 - 8.7e-16 57.9 0.0 1.5e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 ACL97209.1 - 1.2e-12 47.6 0.0 1.7e-12 47.1 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 ACL97209.1 - 1.1e-11 44.3 0.0 2.9e-11 42.9 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 ACL97209.1 - 4.8e-09 36.0 1.1 2.9e-05 23.6 0.5 3.0 2 1 0 2 2 2 2 short chain dehydrogenase NAD_binding_4 PF07993.12 ACL97209.1 - 1.9e-08 33.8 0.0 1.2e-06 27.9 0.0 2.5 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 ACL97209.1 - 0.00037 20.5 0.4 0.0011 19.0 0.1 1.8 3 0 0 3 3 3 1 KR domain NAD_binding_10 PF13460.6 ACL97209.1 - 0.019 14.9 0.2 0.034 14.0 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 ACL97209.1 - 0.076 13.3 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Formyl_trans_N PF00551.19 ACL97210.1 - 2e-32 112.4 0.0 2.8e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 ACL97210.1 - 1.4e-08 34.4 0.0 2.8e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 ACL97210.1 - 0.00015 21.7 0.0 0.00031 20.7 0.0 1.5 1 0 0 1 1 1 1 ACT domain RPEL PF02755.15 ACL97210.1 - 0.18 11.5 0.1 0.45 10.3 0.1 1.7 1 0 0 1 1 1 0 RPEL repeat Peptidase_M20 PF01546.28 ACL97211.1 - 4.9e-39 134.2 0.1 7e-39 133.7 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ACL97211.1 - 4.4e-21 74.9 0.0 8.4e-21 73.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.14 ACL97211.1 - 0.025 13.6 0.0 0.11 11.4 0.0 2.0 1 1 1 2 2 2 0 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.17 ACL97211.1 - 0.027 14.2 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 HEM4 PF02602.15 ACL97211.1 - 0.098 12.0 0.7 1.1 8.5 0.0 2.4 3 0 0 3 3 3 0 Uroporphyrinogen-III synthase HemD Glycos_transf_2 PF00535.26 ACL97212.1 - 4.2e-22 78.7 0.0 5.8e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ACL97212.1 - 8.5e-17 61.8 0.0 1.7e-16 60.8 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 ACL97212.1 - 7.9e-07 28.8 0.0 0.0023 17.4 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 ACL97212.1 - 0.00015 21.3 0.0 0.00042 19.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 ACL97212.1 - 0.00079 19.4 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_7C PF02709.14 ACL97212.1 - 0.17 11.6 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase dTDP_sugar_isom PF00908.17 ACL97213.1 - 1.8e-70 236.0 0.0 2e-70 235.8 0.0 1.0 1 0 0 1 1 1 1 dTDP-4-dehydrorhamnose 3,5-epimerase Bestrophin PF01062.21 ACL97213.1 - 0.17 11.3 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel Abhydrolase_1 PF00561.20 ACL97214.1 - 2e-15 57.1 0.0 3.8e-15 56.2 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ACL97214.1 - 1.3e-14 55.3 7.4 1.8e-14 54.9 7.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ACL97214.1 - 8.1e-12 44.9 0.0 1.5e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 AXE1 PF05448.12 ACL97214.1 - 0.00034 19.4 0.0 0.4 9.3 0.2 2.2 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) PGAP1 PF07819.13 ACL97214.1 - 0.034 13.9 0.0 1.3 8.6 0.0 2.1 1 1 0 1 1 1 0 PGAP1-like protein PALP PF00291.25 ACL97215.2 - 1.3e-70 238.1 0.9 2.1e-70 237.5 0.9 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACT_4 PF13291.6 ACL97215.2 - 4e-10 40.1 0.0 9.9e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT PF01842.25 ACL97215.2 - 2.6e-08 33.5 0.2 5.6e-08 32.4 0.2 1.6 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 ACL97215.2 - 0.0003 20.7 0.1 0.00093 19.1 0.1 1.9 1 1 0 1 1 1 1 ACT domain FKBP_C PF00254.28 ACL97216.2 - 2.1e-23 82.4 0.0 3e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.18 ACL97216.2 - 2.4e-10 41.2 0.0 3.4e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase NTP_transferase PF00483.23 ACL97217.3 - 1.5e-20 73.8 0.0 2.2e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 ACL97217.3 - 0.00043 20.7 0.0 0.00058 20.3 0.0 1.5 1 1 0 1 1 1 1 MobA-like NTP transferase domain CoA_transf_3 PF02515.17 ACL97217.3 - 0.017 14.3 0.2 0.024 13.8 0.2 1.1 1 0 0 1 1 1 0 CoA-transferase family III DUF1730 PF08331.10 ACL97218.1 - 8.2e-21 73.7 0.0 1.3e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1730) Fer4_16 PF13484.6 ACL97218.1 - 7.4e-20 71.7 3.3 1.2e-19 70.9 3.3 1.4 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 ACL97218.1 - 3.5e-07 30.7 5.0 7.9e-07 29.6 5.0 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 ACL97218.1 - 1.9e-05 24.6 4.0 0.022 14.9 1.3 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 ACL97218.1 - 4.2e-05 23.4 8.2 0.028 14.5 2.9 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain HEAT_2 PF13646.6 ACL97218.1 - 0.00021 21.6 0.2 0.00073 19.9 0.2 1.9 1 0 0 1 1 1 1 HEAT repeats Fer4_8 PF13183.6 ACL97218.1 - 0.00024 21.5 0.1 0.023 15.1 0.0 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4 PF00037.27 ACL97218.1 - 0.00045 19.9 10.5 0.0009 19.0 2.4 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_17 PF13534.6 ACL97218.1 - 0.0012 19.4 0.7 0.3 11.7 0.2 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_3 PF12798.7 ACL97218.1 - 0.0013 19.5 10.5 0.095 13.7 3.8 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 ACL97218.1 - 0.0017 18.4 12.6 0.0062 16.6 4.4 3.0 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_21 PF14697.6 ACL97218.1 - 0.0022 18.1 6.3 0.37 10.9 1.9 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 ACL97218.1 - 0.0076 16.4 8.9 0.066 13.4 2.0 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.6 ACL97218.1 - 0.015 15.5 1.5 0.84 9.9 0.4 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain HEAT_EZ PF13513.6 ACL97218.1 - 0.048 14.2 0.1 0.16 12.5 0.1 1.9 1 0 0 1 1 1 0 HEAT-like repeat HEAT PF02985.22 ACL97218.1 - 0.091 13.1 0.2 0.27 11.6 0.2 1.8 1 0 0 1 1 1 0 HEAT repeat Fer4_4 PF12800.7 ACL97218.1 - 0.24 12.0 7.4 7.1 7.4 3.4 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain GST_N_3 PF13417.6 ACL97219.2 - 5.2e-13 49.2 0.0 1.2e-12 48.0 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ACL97219.2 - 2.4e-10 40.6 0.0 4.6e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ACL97219.2 - 1.6e-07 31.5 0.0 2.9e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ACL97219.2 - 4.9e-07 29.9 0.0 9.3e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ACL97219.2 - 5e-07 29.8 0.0 2.4e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ACL97219.2 - 4.1e-05 23.5 2.3 6.3e-05 22.9 0.8 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain PfkB PF00294.24 ACL97220.2 - 1.7e-38 132.6 7.6 2.7e-38 132.0 7.6 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase CTP_transf_like PF01467.26 ACL97220.2 - 8.7e-14 51.9 0.0 1.8e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like Phos_pyr_kin PF08543.12 ACL97220.2 - 7.5e-07 28.8 2.5 1.1e-05 25.0 0.7 2.9 3 0 0 3 3 3 1 Phosphomethylpyrimidine kinase Pantoate_ligase PF02569.15 ACL97220.2 - 0.011 15.0 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase FAD_syn PF06574.12 ACL97220.2 - 0.033 14.1 0.0 0.1 12.4 0.0 1.8 1 1 0 1 1 1 0 FAD synthetase Cation_efflux PF01545.21 ACL97221.1 - 3.1e-31 108.7 13.0 3.9e-31 108.4 13.0 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 ACL97221.1 - 4.3e-20 71.6 0.1 7e-20 71.0 0.1 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Citrate_synt PF00285.21 ACL97222.1 - 1.1e-92 310.9 0.0 1.2e-92 310.7 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Ub-RnfH PF03658.14 ACL97222.1 - 0.04 14.3 0.0 0.097 13.1 0.0 1.6 1 0 0 1 1 1 0 RnfH family Ubiquitin SHNi-TPR PF10516.9 ACL97222.1 - 0.13 11.7 0.3 13 5.4 0.1 2.7 2 1 0 2 2 2 0 SHNi-TPR Citrate_synt PF00285.21 ACL97223.1 - 4.1e-58 197.2 0.6 3.8e-53 180.8 0.9 2.2 2 0 0 2 2 2 2 Citrate synthase, C-terminal domain HTH_17 PF12728.7 ACL97223.1 - 4.9e-06 26.6 0.1 2.3e-05 24.5 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain MerR_1 PF13411.6 ACL97223.1 - 0.022 14.8 0.0 0.8 9.8 0.0 2.4 2 0 0 2 2 2 0 MerR HTH family regulatory protein Lactamase_B PF00753.27 ACL97224.1 - 9.3e-10 38.8 1.4 9.3e-10 38.8 1.4 2.0 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ACL97224.1 - 1.3e-09 37.9 0.1 4.8e-06 26.2 0.1 2.2 2 0 0 2 2 2 2 Beta-lactamase superfamily domain RMMBL PF07521.12 ACL97224.1 - 0.00039 20.3 0.2 0.0051 16.7 0.0 2.6 3 0 0 3 3 3 1 Zn-dependent metallo-hydrolase RNA specificity domain 4HBT PF03061.22 ACL97225.2 - 1.3e-12 47.9 0.3 1.8e-12 47.5 0.3 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 ACL97225.2 - 5.3e-07 30.1 0.1 7.5e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 ACL97226.1 - 2.2e-12 47.1 0.0 3.5e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 ACL97226.1 - 3.8e-07 30.6 0.3 5.3e-07 30.1 0.1 1.3 2 0 0 2 2 2 1 Thioesterase-like superfamily TPP_enzyme_N PF02776.18 ACL97227.1 - 0.089 12.4 0.3 0.092 12.3 0.3 1.0 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Hist_deacetyl PF00850.19 ACL97228.1 - 8.8e-50 169.9 0.0 1.7e-49 168.9 0.0 1.4 1 1 0 1 1 1 1 Histone deacetylase domain 4HBT_3 PF13622.6 ACL97229.1 - 3.8e-62 210.8 1.3 4.6e-62 210.5 1.3 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 ACL97229.1 - 5.9e-44 149.1 0.0 7.2e-35 119.7 0.0 3.1 2 1 0 2 2 2 2 Acyl-CoA thioesterase NUDIX PF00293.28 ACL97230.1 - 6.2e-15 55.4 0.1 1.2e-14 54.5 0.1 1.4 1 1 1 2 2 2 1 NUDIX domain RimM PF01782.18 ACL97231.1 - 4.9e-17 61.9 0.0 7.8e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 RimM N-terminal domain PRC PF05239.16 ACL97231.1 - 4.6e-09 36.2 0.0 7.7e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 PRC-barrel domain Ribosomal_S16 PF00886.19 ACL97232.1 - 1.3e-25 89.2 0.1 2.3e-25 88.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S16 PHY PF00360.20 ACL97232.1 - 0.0024 17.2 0.3 0.003 16.9 0.3 1.1 1 0 0 1 1 1 1 Phytochrome region IHO1 PF15771.5 ACL97232.1 - 0.014 14.2 0.5 0.015 14.1 0.5 1.0 1 0 0 1 1 1 0 Interactor of HORMAD1 protein 1 BCL_N PF04714.13 ACL97232.1 - 3 8.0 4.5 2.4 8.3 0.2 2.2 2 0 0 2 2 2 0 BCL7, N-terminal conserver region Borrelia_P83 PF05262.11 ACL97232.1 - 3.8 5.9 12.4 4 5.8 12.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein SRP54 PF00448.22 ACL97233.1 - 2e-65 220.1 0.2 3.9e-65 219.2 0.2 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 ACL97233.1 - 7.7e-31 106.6 1.7 2.4e-30 105.1 1.7 1.9 1 0 0 1 1 1 1 Signal peptide binding domain SRP54_N PF02881.19 ACL97233.1 - 4.9e-19 68.3 0.2 1.5e-18 66.8 0.2 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.23 ACL97233.1 - 2.4e-06 27.6 0.2 3.2e-05 24.0 0.0 2.8 3 1 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 ACL97233.1 - 0.0001 21.7 0.0 0.00019 20.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin DnaB_C PF03796.15 ACL97233.1 - 0.00027 20.3 0.1 0.00063 19.2 0.1 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_25 PF13481.6 ACL97233.1 - 0.001 18.7 1.1 0.0085 15.7 0.3 2.5 2 0 0 2 2 2 1 AAA domain AAA_31 PF13614.6 ACL97233.1 - 0.0012 18.8 0.5 0.0054 16.7 0.2 2.1 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 ACL97233.1 - 0.0021 18.3 0.1 0.0044 17.2 0.1 1.6 1 0 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 ACL97233.1 - 0.0068 15.6 5.6 0.0068 15.6 0.5 2.9 2 2 0 3 3 3 1 Anion-transporting ATPase AAA_16 PF13191.6 ACL97233.1 - 0.091 13.1 1.3 0.15 12.4 0.2 1.9 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 ACL97233.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain ResIII PF04851.15 ACL97233.1 - 0.21 11.6 0.0 0.45 10.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DXP_reductoisom PF02670.16 ACL97233.1 - 0.24 12.1 1.7 4.5 8.0 0.3 2.6 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase TipAS PF07739.13 ACL97233.1 - 0.64 10.6 3.0 0.41 11.2 0.2 2.0 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Adaptin_binding PF10199.9 ACL97233.1 - 0.68 10.6 2.9 8.5 7.0 0.3 2.4 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 DUF1993 PF09351.10 ACL97234.2 - 4.1e-60 202.6 0.0 4.6e-60 202.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) Ldh_1_N PF00056.23 ACL97235.1 - 1.6e-39 135.2 0.2 2.5e-39 134.6 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 ACL97235.1 - 1.2e-28 100.1 0.0 1.8e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain UDPG_MGDP_dh_N PF03721.14 ACL97235.1 - 0.0035 16.9 0.3 0.0099 15.5 0.3 1.7 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 ACL97235.1 - 0.024 14.5 0.4 0.058 13.3 0.4 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.16 ACL97235.1 - 0.038 13.5 0.3 0.17 11.5 0.0 2.0 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase NAD_binding_8 PF13450.6 ACL97235.1 - 0.11 12.8 0.7 0.62 10.3 0.2 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain MaoC_dehydratas PF01575.19 ACL97236.1 - 6.5e-10 38.6 0.0 1e-08 34.8 0.0 2.0 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.6 ACL97236.1 - 5.9e-05 23.2 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase HIT PF01230.23 ACL97237.1 - 1.4e-18 67.5 0.0 1.6e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 HIT domain XdhC_CoxI PF02625.16 ACL97237.1 - 0.024 14.8 0.5 0.087 13.0 0.5 2.3 1 1 0 1 1 1 0 XdhC and CoxI family DUF3182 PF11379.8 ACL97238.1 - 0.053 12.5 0.3 0.086 11.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) HpcH_HpaI PF03328.14 ACL97239.1 - 6.3e-43 146.5 1.7 7.9e-43 146.1 1.7 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 ACL97239.1 - 1.9e-08 33.9 0.5 0.0012 18.0 0.0 2.4 3 0 0 3 3 3 2 C-C_Bond_Lyase of the TIM-Barrel fold DUF2237 PF09996.9 ACL97240.1 - 1.6e-54 182.8 0.0 1.9e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) LigT_PEase PF02834.16 ACL97241.1 - 9e-29 99.5 0.1 5.1e-14 52.2 0.0 2.0 2 0 0 2 2 2 2 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.6 ACL97241.1 - 1.1e-17 64.4 0.1 1.4e-17 64.0 0.1 1.0 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Aldo_ket_red PF00248.21 ACL97242.1 - 1.9e-63 214.4 0.0 2.2e-63 214.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Bax1-I PF01027.20 ACL97243.1 - 2e-56 191.1 26.5 2.3e-56 190.9 26.5 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF3054 PF11255.8 ACL97243.1 - 0.39 11.3 9.1 0.12 12.9 5.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3054) DUF2794 PF10984.8 ACL97244.1 - 6.8e-40 135.1 0.1 8.1e-40 134.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2794) DUF1223 PF06764.11 ACL97245.2 - 4.4e-57 193.4 0.0 5.1e-57 193.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1223) DUF1455 PF07306.11 ACL97245.2 - 0.027 14.5 0.3 0.047 13.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1455) Thioredoxin_3 PF13192.6 ACL97245.2 - 0.041 13.9 0.0 2.9 8.0 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin domain Aconitase PF00330.20 ACL97246.1 - 4.4e-183 609.5 0.0 5.7e-183 609.1 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ACL97246.1 - 1.6e-44 151.4 0.0 2.9e-44 150.6 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain ABC_tran PF00005.27 ACL97247.1 - 2.4e-23 83.1 0.0 3e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ACL97247.1 - 7.7e-07 29.2 0.1 7e-05 22.8 0.0 2.1 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ACL97247.1 - 1.4e-06 28.0 0.0 0.055 12.9 0.0 2.7 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ACL97247.1 - 9.6e-05 22.0 0.1 0.00018 21.2 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF2813 PF11398.8 ACL97247.1 - 0.0065 15.8 0.0 0.0085 15.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2813) AAA_23 PF13476.6 ACL97247.1 - 0.016 15.8 0.0 0.021 15.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ACL97247.1 - 0.016 14.9 2.2 0.03 14.0 2.2 1.5 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 ACL97247.1 - 0.017 15.1 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 ACL97247.1 - 0.024 15.0 3.5 0.04 14.3 3.5 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.6 ACL97247.1 - 0.033 13.9 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_27 PF13514.6 ACL97247.1 - 0.044 13.4 0.1 0.096 12.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 ACL97247.1 - 0.11 12.8 0.1 0.17 12.2 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 ACL97247.1 - 0.12 12.8 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF3584 PF12128.8 ACL97247.1 - 0.15 9.5 0.2 0.2 9.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TsaE PF02367.17 ACL97247.1 - 0.17 11.9 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CcmB PF03379.13 ACL97248.1 - 1.7e-55 187.9 22.4 1.9e-55 187.7 22.4 1.0 1 0 0 1 1 1 1 CcmB protein ABC2_membrane PF01061.24 ACL97248.1 - 0.0002 20.9 0.3 0.0002 20.9 0.3 1.7 1 1 1 2 2 2 1 ABC-2 type transporter ABC2_membrane_2 PF12679.7 ACL97248.1 - 0.063 12.6 9.9 0.037 13.3 8.1 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein ThrE PF06738.12 ACL97248.1 - 0.084 12.2 5.7 0.067 12.5 4.6 1.5 1 1 0 1 1 1 0 Putative threonine/serine exporter B12D PF06522.11 ACL97248.1 - 0.36 10.7 0.8 1.1 9.1 0.8 1.9 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit EamA PF00892.20 ACL97249.2 - 4.8e-29 101.3 39.5 1.6e-15 57.5 13.2 2.0 2 0 0 2 2 2 2 EamA-like transporter family DUF2339 PF10101.9 ACL97249.2 - 0.11 11.1 40.9 0.13 10.8 40.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) TPT PF03151.16 ACL97249.2 - 0.12 11.7 7.7 0.49 9.7 1.8 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family Phage_holin_5_2 PF16079.5 ACL97249.2 - 9.4 6.6 14.4 1 9.7 0.9 3.3 2 1 1 3 3 3 0 Phage holin family Hol44, in holin superfamily V Cytochrom_C_asm PF01578.20 ACL97251.1 - 1.7e-31 109.6 11.5 3.2e-31 108.8 11.5 1.4 1 0 0 1 1 1 1 Cytochrome C assembly protein Ytca PF17090.5 ACL97251.1 - 5.6 7.6 9.2 0.16 12.5 1.4 2.5 3 0 0 3 3 3 0 Uncharacterised protein family CcmD PF04995.14 ACL97252.1 - 2.4e-14 53.1 1.9 2.8e-14 52.9 1.9 1.0 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) MerR-DNA-bind PF09278.11 ACL97252.1 - 0.014 15.9 0.1 0.015 15.8 0.1 1.1 1 0 0 1 1 1 0 MerR, DNA binding Redoxin PF08534.10 ACL97253.1 - 3.6e-14 52.7 0.0 4.7e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 ACL97253.1 - 3.9e-10 39.7 0.0 5e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.20 ACL97253.1 - 2e-06 27.7 0.0 5.1e-05 23.2 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ACL97253.1 - 3.6e-05 24.2 0.0 5.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ACL97253.1 - 5.2e-05 23.5 0.0 8.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 ACL97253.1 - 0.077 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like TraF PF13728.6 ACL97253.1 - 0.14 12.0 0.0 0.79 9.5 0.0 1.9 1 1 1 2 2 2 0 F plasmid transfer operon protein DSBA PF01323.20 ACL97253.1 - 0.17 11.7 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 DSBA-like thioredoxin domain FAP PF07174.11 ACL97255.1 - 0.1 12.0 7.9 0.1 12.0 7.9 1.0 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) MarR_2 PF12802.7 ACL97256.1 - 8.6e-14 51.2 3.9 1.5e-13 50.4 1.5 2.4 3 0 0 3 3 3 1 MarR family MarR PF01047.22 ACL97256.1 - 2.7e-12 46.4 0.0 1.6e-11 43.9 0.1 2.0 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.6 ACL97256.1 - 1e-10 41.9 0.7 3.1e-10 40.4 0.5 1.9 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_24 PF13412.6 ACL97256.1 - 1.8e-05 24.2 0.0 4.2e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 ACL97256.1 - 6.1e-05 22.8 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_34 PF13601.6 ACL97256.1 - 0.00023 21.3 0.0 0.00042 20.5 0.0 1.4 1 0 0 1 1 1 1 Winged helix DNA-binding domain HTH_IclR PF09339.10 ACL97256.1 - 0.00028 20.6 2.0 0.00028 20.6 0.6 1.8 2 0 0 2 2 2 1 IclR helix-turn-helix domain FeoC PF09012.10 ACL97256.1 - 0.0047 17.0 0.0 0.0099 15.9 0.0 1.5 1 0 0 1 1 1 1 FeoC like transcriptional regulator HTH_29 PF13551.6 ACL97256.1 - 0.0094 16.0 0.3 0.023 14.7 0.3 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 ACL97256.1 - 0.012 15.7 0.1 0.032 14.3 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_45 PF14947.6 ACL97256.1 - 0.031 14.3 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix RepB PF07506.11 ACL97256.1 - 0.038 14.1 2.7 0.13 12.3 2.7 2.0 1 1 0 1 1 1 0 RepB plasmid partitioning protein HTH_26 PF13443.6 ACL97256.1 - 0.053 14.0 0.0 0.091 13.2 0.0 1.4 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain DUF3489 PF11994.8 ACL97256.1 - 0.053 13.6 0.1 7.2 6.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3489) HTH_1 PF00126.27 ACL97256.1 - 0.55 10.2 4.7 2.8 8.0 2.4 2.7 2 1 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family IspA PF04279.15 ACL97257.1 - 3.6e-47 160.8 9.4 4.1e-47 160.6 9.4 1.0 1 0 0 1 1 1 1 Intracellular septation protein A DUF2061 PF09834.9 ACL97257.1 - 0.06 13.9 0.9 0.06 13.9 0.9 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2061) ABC2_membrane_5 PF13346.6 ACL97257.1 - 0.3 10.6 0.1 0.3 10.6 0.1 2.3 2 1 0 2 2 2 0 ABC-2 family transporter protein MerC PF03203.14 ACL97257.1 - 1.8 9.0 10.5 1.2 9.6 5.0 2.2 1 1 1 2 2 2 0 MerC mercury resistance protein SRP54 PF00448.22 ACL97258.1 - 1.9e-71 239.7 0.2 2.7e-71 239.3 0.2 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 ACL97258.1 - 6.1e-09 36.0 0.3 1.4e-08 34.8 0.3 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_17 PF13207.6 ACL97258.1 - 7.4e-07 29.7 0.2 1.8e-06 28.4 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 ACL97258.1 - 7.6e-07 29.0 1.8 8.8e-07 28.8 0.7 1.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ACL97258.1 - 6.1e-06 26.7 0.8 4.1e-05 24.0 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 ACL97258.1 - 8e-06 25.3 0.0 1.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin MeaB PF03308.16 ACL97258.1 - 0.00011 21.3 0.8 0.00065 18.8 0.8 2.0 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 ACL97258.1 - 0.00016 22.1 0.0 0.00036 21.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_31 PF13614.6 ACL97258.1 - 0.00025 21.0 0.4 0.023 14.6 0.3 2.3 1 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 ACL97258.1 - 0.00045 19.6 0.1 0.0006 19.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 ACL97258.1 - 0.00071 19.4 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 ACL97258.1 - 0.00081 19.3 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 ACL97258.1 - 0.0013 18.9 0.0 0.0022 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 ACL97258.1 - 0.0016 18.5 0.2 0.009 16.1 0.2 2.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 ACL97258.1 - 0.0038 17.1 0.5 0.53 10.2 0.2 2.4 2 0 0 2 2 2 1 NTPase VirC1 PF07015.11 ACL97258.1 - 0.0046 16.3 0.0 0.0067 15.8 0.0 1.2 1 0 0 1 1 1 1 VirC1 protein Lipase_GDSL_2 PF13472.6 ACL97258.1 - 0.0067 16.8 0.1 0.01 16.2 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family ResIII PF04851.15 ACL97258.1 - 0.011 15.7 0.0 0.097 12.7 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 ACL97258.1 - 0.012 15.4 0.2 0.025 14.5 0.2 1.5 1 0 0 1 1 1 0 Helicase NACHT PF05729.12 ACL97258.1 - 0.019 14.9 0.3 0.063 13.2 0.1 2.0 3 0 0 3 3 2 0 NACHT domain ArsA_ATPase PF02374.15 ACL97258.1 - 0.019 14.2 2.6 1.2 8.2 0.8 2.4 1 1 1 2 2 2 0 Anion-transporting ATPase AAA_22 PF13401.6 ACL97258.1 - 0.019 15.2 0.1 0.087 13.1 0.1 2.2 1 1 0 1 1 1 0 AAA domain MobB PF03205.14 ACL97258.1 - 0.025 14.5 0.3 0.047 13.6 0.3 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.27 ACL97258.1 - 0.027 15.0 0.0 0.08 13.5 0.0 1.8 2 0 0 2 2 2 0 ABC transporter cobW PF02492.19 ACL97258.1 - 0.027 14.0 1.1 0.12 11.9 1.1 1.9 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 ACL97258.1 - 0.028 14.7 0.1 0.061 13.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.18 ACL97258.1 - 0.035 13.5 0.0 0.31 10.4 0.0 2.1 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_19 PF13245.6 ACL97258.1 - 0.037 14.4 0.4 0.09 13.1 0.4 1.6 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 ACL97258.1 - 0.04 13.6 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 Thymidylate kinase AAA_23 PF13476.6 ACL97258.1 - 0.046 14.2 0.1 0.098 13.1 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 ACL97258.1 - 0.064 12.8 1.8 0.29 10.7 1.8 2.0 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 ACL97258.1 - 0.11 11.5 0.0 0.22 10.6 0.0 1.5 1 1 0 1 1 1 0 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 ACL97258.1 - 0.12 11.3 1.0 0.15 10.9 0.1 1.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain PduV-EutP PF10662.9 ACL97258.1 - 0.14 11.9 0.2 19 5.0 0.1 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 ACL97258.1 - 0.14 11.9 0.0 0.36 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TFIIA_gamma_N PF02268.16 ACL97258.1 - 0.15 12.1 0.1 0.53 10.3 0.0 1.9 2 0 0 2 2 1 0 Transcription initiation factor IIA, gamma subunit, helical domain MipZ PF09140.11 ACL97258.1 - 0.15 11.3 0.6 4 6.6 0.6 2.2 1 1 0 1 1 1 0 ATPase MipZ DUF87 PF01935.17 ACL97258.1 - 0.43 10.6 2.1 0.43 10.6 0.7 1.7 2 0 0 2 2 1 0 Helicase HerA, central domain NBD_C PF17042.5 ACL97258.1 - 0.96 9.9 6.8 1.4 9.4 0.4 3.0 2 2 1 3 3 3 0 Nucleotide-binding C-terminal domain UPF0126 PF03458.13 ACL97259.2 - 3.6e-37 126.1 28.0 2.3e-19 69.1 6.4 2.4 3 0 0 3 3 3 2 UPF0126 domain PhrC_PhrF PF11131.8 ACL97259.2 - 0.29 10.8 6.6 2.5 7.8 0.7 2.6 2 0 0 2 2 2 0 Rap-phr extracellular signalling TerB PF05099.13 ACL97260.2 - 1.6e-26 93.0 5.3 1.9e-26 92.7 5.3 1.0 1 0 0 1 1 1 1 Tellurite resistance protein TerB DUF533 PF04391.12 ACL97260.2 - 5.2e-06 26.2 0.1 0.0036 16.9 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF533) TPR_16 PF13432.6 ACL97260.2 - 0.15 12.7 6.3 0.42 11.3 6.3 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat TerC PF03741.16 ACL97261.1 - 8e-54 182.1 14.1 8e-54 182.1 14.1 1.9 2 0 0 2 2 2 1 Integral membrane protein TerC family GFA PF04828.14 ACL97262.1 - 3.2e-14 53.0 0.1 4.3e-14 52.6 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Radical_SAM PF04055.21 ACL97263.1 - 3.1e-24 86.2 0.0 1.2e-23 84.3 0.0 2.0 3 0 0 3 3 3 1 Radical SAM superfamily UPF0004 PF00919.20 ACL97263.1 - 1.2e-17 63.7 0.1 3.6e-17 62.2 0.1 1.8 1 1 0 1 1 1 1 Uncharacterized protein family UPF0004 B12-binding PF02310.19 ACL97263.1 - 5.5e-05 23.2 0.3 0.00016 21.7 0.2 1.9 2 0 0 2 2 2 1 B12 binding domain adh_short PF00106.25 ACL97264.3 - 1.5e-41 142.0 0.7 2e-41 141.6 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ACL97264.3 - 7e-31 107.6 0.5 9e-31 107.2 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 2-Hacid_dh_C PF02826.19 ACL97264.3 - 0.0013 18.1 0.1 0.018 14.4 0.2 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain KR PF08659.10 ACL97264.3 - 0.0058 16.5 1.1 0.013 15.5 1.1 1.6 1 1 0 1 1 1 1 KR domain DAP_epimerase PF01678.19 ACL97265.1 - 6.6e-48 161.9 0.6 1.5e-25 89.7 0.1 2.1 2 0 0 2 2 2 2 Diaminopimelate epimerase Peptidase_S9 PF00326.21 ACL97266.1 - 3.4e-44 150.9 0.1 5.7e-44 150.1 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 ACL97266.1 - 8.3e-26 90.7 0.0 4.5e-23 81.7 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase, N-terminal beta-propeller domain Hydrolase_4 PF12146.8 ACL97266.1 - 0.0053 16.0 0.0 0.019 14.2 0.0 1.7 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 ACL97266.1 - 0.023 14.3 0.0 0.048 13.3 0.0 1.5 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 ACL97267.1 - 2.9e-50 170.7 0.0 4.8e-50 170.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 ACL97267.1 - 2.7e-39 135.1 0.0 3.7e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S15 PF02129.18 ACL97267.1 - 7.3e-05 22.5 0.2 0.00017 21.3 0.2 1.6 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 ACL97267.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Acetyltransf_6 PF13480.7 ACL97268.1 - 1.8e-30 106.0 0.9 4e-30 104.8 0.9 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2218 PF09981.9 ACL97269.3 - 5e-33 113.3 0.6 6.1e-33 113.1 0.6 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2218) PadR PF03551.14 ACL97270.1 - 6.4e-18 64.5 0.0 9.7e-18 63.9 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family NIR_SIR_ferr PF03460.17 ACL97270.1 - 0.026 14.4 0.1 0.05 13.5 0.1 1.5 1 0 0 1 1 1 0 Nitrite/Sulfite reductase ferredoxin-like half domain HTH_27 PF13463.6 ACL97270.1 - 0.049 14.1 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain FUR PF01475.19 ACL97270.1 - 0.091 12.9 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Ferric uptake regulator family HTH_34 PF13601.6 ACL97270.1 - 0.14 12.4 0.0 0.24 11.6 0.0 1.5 1 1 0 1 1 1 0 Winged helix DNA-binding domain MlaA PF04333.13 ACL97271.1 - 5.9e-64 215.4 0.1 7.2e-64 215.1 0.1 1.1 1 0 0 1 1 1 1 MlaA lipoprotein MlaC PF05494.12 ACL97272.1 - 1.8e-42 144.9 1.3 2.2e-42 144.6 1.3 1.1 1 0 0 1 1 1 1 MlaC protein DUF3760 PF12586.8 ACL97272.1 - 0.22 11.8 0.0 0.4 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) MlaD PF02470.20 ACL97273.1 - 1.8e-20 73.0 0.0 2.6e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 MlaD protein BclA_C PF18573.1 ACL97273.1 - 0.0038 17.1 0.4 0.014 15.3 0.1 1.9 2 0 0 2 2 2 1 BclA C-terminal domain MlaE PF02405.16 ACL97274.1 - 7.2e-78 261.1 15.4 7.2e-78 261.1 15.4 1.5 2 0 0 2 2 2 1 Permease MlaE ABC_tran PF00005.27 ACL97275.1 - 4.7e-29 101.7 0.0 6e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ACL97275.1 - 2.2e-05 24.4 0.6 0.00017 21.5 0.0 2.0 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system Mg_chelatase PF01078.21 ACL97275.1 - 0.016 14.6 0.0 0.049 13.0 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 ACL97275.1 - 0.031 14.7 0.7 0.07 13.5 0.7 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 ACL97275.1 - 0.04 14.2 0.0 0.063 13.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 ACL97275.1 - 0.068 13.5 0.4 0.1 12.9 0.3 1.5 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.7 ACL97275.1 - 0.13 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_29 PF13555.6 ACL97275.1 - 0.16 11.8 0.1 0.29 10.9 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain LysR_substrate PF03466.20 ACL97276.1 - 1.8e-43 148.4 6.0 2.3e-43 148.0 6.0 1.1 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 ACL97276.1 - 4.2e-19 68.2 0.4 4.2e-19 68.2 0.4 1.8 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_30 PF13556.6 ACL97276.1 - 0.016 15.0 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain CMD PF02627.20 ACL97277.1 - 1e-11 44.7 14.7 1.9e-11 43.8 4.5 2.1 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family SHE3 PF17078.5 ACL97278.1 - 0.0007 19.4 6.2 0.0007 19.4 6.2 3.0 1 1 1 2 2 2 1 SWI5-dependent HO expression protein 3 BLOC1_2 PF10046.9 ACL97278.1 - 0.0025 18.1 18.6 0.031 14.6 0.1 5.3 3 2 2 6 6 5 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 GAS PF13851.6 ACL97278.1 - 0.0062 15.9 34.8 0.016 14.6 5.7 3.8 1 1 2 3 3 3 2 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 ACL97278.1 - 0.009 14.9 44.4 0.31 9.9 10.9 4.5 1 1 4 5 5 5 3 Spc7 kinetochore protein DUF3450 PF11932.8 ACL97278.1 - 0.0094 15.3 7.2 0.0094 15.3 7.2 4.3 2 1 3 5 5 4 1 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.9 ACL97278.1 - 0.038 14.0 35.9 0.15 12.1 1.9 4.6 1 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Occludin_ELL PF07303.13 ACL97278.1 - 0.32 11.8 10.0 1.4 9.6 0.1 4.5 2 2 3 5 5 5 0 Occludin homology domain Fib_alpha PF08702.10 ACL97278.1 - 0.37 11.0 16.8 3.2 7.9 0.2 3.5 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family MscS_porin PF12795.7 ACL97278.1 - 0.52 9.8 71.8 1.4 8.4 23.0 3.4 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain NPV_P10 PF05531.12 ACL97278.1 - 0.83 10.2 15.3 32 5.1 1.0 6.0 3 1 2 5 5 5 0 Nucleopolyhedrovirus P10 protein Csm2_III-A PF03750.13 ACL97278.1 - 0.84 10.5 5.3 10 7.0 2.5 2.8 2 0 0 2 2 2 0 Csm2 Type III-A ATG16 PF08614.11 ACL97278.1 - 0.99 9.6 64.4 1.2 9.4 9.7 4.0 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) MitMem_reg PF13012.6 ACL97278.1 - 1.2 9.6 9.0 1.3 9.5 0.7 3.5 3 1 0 3 3 3 0 Maintenance of mitochondrial structure and function ADIP PF11559.8 ACL97278.1 - 1.5 8.9 49.6 1.1 9.3 1.5 6.2 1 1 5 6 6 6 0 Afadin- and alpha -actinin-Binding UPF0184 PF03670.13 ACL97278.1 - 1.6 9.2 12.4 9.2 6.7 0.1 4.7 2 2 2 5 5 5 0 Uncharacterised protein family (UPF0184) PI3K_P85_iSH2 PF16454.5 ACL97278.1 - 1.6 8.3 22.5 0.29 10.7 2.3 4.2 2 1 2 4 4 4 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Dynactin_p22 PF07426.11 ACL97278.1 - 2.1 8.2 11.4 0.65 9.8 2.4 3.1 3 1 0 3 3 3 0 Dynactin subunit p22 DUF16 PF01519.16 ACL97278.1 - 2.5 8.6 19.8 21 5.7 0.7 5.3 3 2 1 4 4 4 0 Protein of unknown function DUF16 YabA PF06156.13 ACL97278.1 - 3.3 8.4 18.5 0.77 10.4 0.4 4.8 1 1 2 4 4 4 0 Initiation control protein YabA UPF0242 PF06785.11 ACL97278.1 - 3.6 7.6 34.0 1.9 8.5 9.3 4.1 1 1 4 5 5 5 0 Uncharacterised protein family (UPF0242) N-terminus Fez1 PF06818.15 ACL97278.1 - 4 7.8 39.3 44 4.4 18.4 3.6 1 1 1 2 2 2 0 Fez1 PKcGMP_CC PF16808.5 ACL97278.1 - 4.5 7.2 13.8 8.7 6.3 0.1 4.6 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Lectin_N PF03954.14 ACL97278.1 - 5.5 6.7 16.0 5.1 6.8 0.7 3.8 3 1 1 4 4 4 0 Hepatic lectin, N-terminal domain JIP_LZII PF16471.5 ACL97278.1 - 5.9 7.2 23.4 0.34 11.1 0.9 5.7 5 2 1 6 6 5 0 JNK-interacting protein leucine zipper II DUF4407 PF14362.6 ACL97278.1 - 6.5 6.0 65.4 1.6 8.0 16.9 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Prefoldin_2 PF01920.20 ACL97278.1 - 7.1 6.6 24.5 3 7.8 0.0 6.7 2 2 5 8 8 8 0 Prefoldin subunit BORCS7 PF16088.5 ACL97278.1 - 7.9 6.8 9.5 2 8.7 1.2 3.8 4 0 0 4 4 4 0 BLOC-1-related complex sub-unit 7 DUF1664 PF07889.12 ACL97278.1 - 8.7 6.4 22.0 26 4.9 0.2 5.3 1 1 3 6 6 6 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 ACL97278.1 - 9.4 6.3 23.3 1.1 9.3 4.0 4.3 1 1 2 4 4 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Polyketide_cyc2 PF10604.9 ACL97279.1 - 6.3e-11 42.7 0.1 8.8e-11 42.3 0.1 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 ACL97279.1 - 8.3e-05 22.8 0.0 0.0001 22.5 0.0 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein TraB PF01963.17 ACL97280.1 - 1.9e-33 116.5 0.0 2.2e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 TraB family Peptidase_M3 PF01432.20 ACL97281.1 - 9.3e-111 371.3 0.0 1.3e-110 370.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 TAT_signal PF10518.9 ACL97281.1 - 0.0012 18.6 1.4 0.0012 18.6 1.4 2.0 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence Asp_Glu_race PF01177.22 ACL97282.2 - 5.1e-22 78.8 0.0 6.1e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase FtsK_SpoIIIE PF01580.18 ACL97284.1 - 3.3e-64 216.5 0.0 6.1e-64 215.7 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family FtsK_alpha PF17854.1 ACL97284.1 - 3e-27 94.7 0.0 5.4e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 FtsK alpha domain FtsK_gamma PF09397.10 ACL97284.1 - 4.9e-26 90.3 0.1 1e-25 89.3 0.1 1.6 1 0 0 1 1 1 1 Ftsk gamma domain FtsK_4TM PF13491.6 ACL97284.1 - 1.7e-21 76.7 12.0 2.8e-21 76.0 12.0 1.2 1 0 0 1 1 1 1 4TM region of DNA translocase FtsK/SpoIIIE AAA_10 PF12846.7 ACL97284.1 - 1.6e-05 24.0 0.0 0.028 13.4 0.0 2.2 2 0 0 2 2 2 2 AAA-like domain DUF87 PF01935.17 ACL97284.1 - 0.003 17.7 0.0 0.0055 16.8 0.0 1.3 1 0 0 1 1 1 1 Helicase HerA, central domain T2SSE PF00437.20 ACL97284.1 - 0.0085 15.2 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 ACL97284.1 - 0.035 13.0 0.0 0.1 11.5 0.0 1.7 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain TniB PF05621.11 ACL97284.1 - 0.12 11.8 0.5 12 5.3 0.0 3.1 3 0 0 3 3 3 0 Bacterial TniB protein AAA_22 PF13401.6 ACL97284.1 - 0.17 12.2 0.1 2 8.7 0.1 2.6 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 ACL97284.1 - 0.17 11.6 0.0 0.42 10.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain LolA PF03548.15 ACL97285.1 - 2.3e-38 131.5 0.0 2.7e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 Outer membrane lipoprotein carrier protein LolA PorA PF11271.8 ACL97285.1 - 0.066 12.5 0.1 0.077 12.3 0.1 1.2 1 0 0 1 1 1 0 Porin PorA LPAM_1 PF08139.12 ACL97285.1 - 0.31 11.6 1.9 0.81 10.3 1.9 1.8 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Exo_endo_phos PF03372.23 ACL97286.1 - 1.3e-20 73.9 0.0 1.8e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 ACL97286.1 - 0.12 12.2 0.0 0.3 11.0 0.0 1.8 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Fapy_DNA_glyco PF01149.24 ACL97287.1 - 2.9e-33 114.9 0.0 4.4e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 ACL97287.1 - 1.2e-23 82.9 0.0 1.8e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain zf-FPG_IleRS PF06827.14 ACL97287.1 - 7.6e-12 44.9 2.6 1.3e-11 44.1 2.6 1.4 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS IBR PF01485.21 ACL97287.1 - 0.16 12.2 0.2 0.23 11.7 0.2 1.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Ubie_methyltran PF01209.18 ACL97288.1 - 2.8e-80 269.0 0.0 3.4e-80 268.7 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 ACL97288.1 - 6.1e-16 58.9 0.0 1.2e-15 57.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ACL97288.1 - 2.4e-14 53.8 0.0 4.7e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ACL97288.1 - 7.9e-09 35.5 0.0 1.2e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ACL97288.1 - 2.7e-08 33.8 0.0 3.5e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ACL97288.1 - 2.1e-07 31.6 0.0 3.3e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 ACL97288.1 - 3.9e-05 23.6 0.0 0.0003 20.7 0.0 2.0 2 0 0 2 2 2 1 Hypothetical methyltransferase NodS PF05401.11 ACL97288.1 - 0.042 13.5 0.0 0.064 12.9 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) ABC1 PF03109.16 ACL97289.1 - 1.4e-27 96.2 0.0 3.4e-27 95.0 0.0 1.6 2 0 0 2 2 2 1 ABC1 family DUF5076 PF16826.5 ACL97290.1 - 1.1e-28 98.9 0.0 1.4e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5076) BDM PF10684.9 ACL97290.1 - 0.16 12.3 0.1 0.27 11.6 0.1 1.3 1 0 0 1 1 1 0 Putative biofilm-dependent modulation protein IMUP PF15761.5 ACL97291.1 - 0.039 14.6 0.5 0.073 13.8 0.5 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein DFP PF04127.15 ACL97292.2 - 7.5e-68 228.0 0.0 7.4e-67 224.8 0.0 2.0 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein Flavoprotein PF02441.19 ACL97292.2 - 1.5e-41 141.8 0.1 3.2e-41 140.7 0.1 1.5 2 0 0 2 2 2 1 Flavoprotein YjeF_N PF03853.15 ACL97292.2 - 9.4e-05 22.4 0.2 0.061 13.2 0.1 2.3 2 0 0 2 2 2 2 YjeF-related protein N-terminus SBP_bac_11 PF13531.6 ACL97292.2 - 0.0047 16.7 2.1 0.0047 16.7 2.1 2.6 1 1 1 2 2 2 1 Bacterial extracellular solute-binding protein NAD_binding_7 PF13241.6 ACL97292.2 - 0.025 15.0 0.3 1.2 9.6 0.1 2.7 2 1 0 2 2 2 0 Putative NAD(P)-binding Glyco_trans_4_4 PF13579.6 ACL97292.2 - 1 9.8 11.1 0.081 13.4 2.8 2.9 2 2 0 2 2 2 0 Glycosyl transferase 4-like domain dUTPase PF00692.19 ACL97293.1 - 4.5e-29 100.7 0.0 5.3e-29 100.5 0.0 1.0 1 0 0 1 1 1 1 dUTPase HlyD_D23 PF16576.5 ACL97295.2 - 2.2e-18 66.3 12.3 1.2e-16 60.5 12.3 2.3 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 ACL97295.2 - 1.4e-16 61.1 11.0 2.1e-14 54.1 1.1 3.3 2 2 1 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 ACL97295.2 - 2.9e-14 52.6 2.4 2.9e-14 52.6 2.4 3.3 3 1 0 3 3 3 2 Biotin-lipoyl like HlyD PF00529.20 ACL97295.2 - 3.7e-05 23.5 21.4 7.5e-05 22.5 21.4 1.7 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl PF00364.22 ACL97295.2 - 7.4e-05 22.5 0.5 0.0076 16.1 0.1 2.4 2 0 0 2 2 2 1 Biotin-requiring enzyme HlyD_2 PF12700.7 ACL97295.2 - 0.0001 21.2 0.0 0.0014 17.5 0.0 2.5 2 1 1 3 3 3 1 HlyD family secretion protein PTS_EIIA_1 PF00358.20 ACL97295.2 - 0.063 13.0 0.1 0.98 9.2 0.0 2.5 2 0 0 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 RnfC_N PF13375.6 ACL97295.2 - 0.1 12.6 2.0 0.48 10.4 0.1 2.7 2 1 0 2 2 2 0 RnfC Barrel sandwich hybrid domain Peptidase_M23 PF01551.22 ACL97295.2 - 0.12 12.6 1.0 8.6 6.6 0.0 3.1 2 1 1 3 3 3 0 Peptidase family M23 MFS_1 PF07690.16 ACL97296.1 - 1.1e-47 162.7 39.2 1.1e-47 162.7 39.2 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TetR_C_7 PF14246.6 ACL97297.1 - 6.3e-24 84.3 2.5 6.3e-24 84.3 2.5 1.7 3 0 0 3 3 3 1 AefR-like transcriptional repressor, C-terminal domain TetR_N PF00440.23 ACL97297.1 - 1.1e-15 57.1 0.2 2.8e-15 55.8 0.1 1.7 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family HTH_Tnp_ISL3 PF13542.6 ACL97297.1 - 0.014 14.8 0.2 0.037 13.4 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 LacI PF00356.21 ACL97297.1 - 0.018 14.8 0.1 0.055 13.3 0.1 1.9 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family HTH_23 PF13384.6 ACL97297.1 - 0.036 13.9 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain HTH_7 PF02796.15 ACL97297.1 - 0.084 13.0 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_38 PF13936.6 ACL97297.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_22 PF13309.6 ACL97297.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 HTH domain TetR_C_11 PF16859.5 ACL97297.1 - 0.13 12.6 0.3 0.13 12.6 0.3 2.5 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HTH_28 PF13518.6 ACL97297.1 - 0.16 12.1 0.5 0.53 10.4 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain adh_short_C2 PF13561.6 ACL97298.2 - 5.8e-80 268.2 3.7 6.6e-80 268.0 3.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ACL97298.2 - 6.3e-20 71.5 0.6 9.7e-20 70.9 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Enoyl_reductase PF12241.8 ACL97298.2 - 6.5e-07 28.9 0.2 0.0083 15.5 0.0 2.7 2 1 1 3 3 3 2 Trans-2-enoyl-CoA reductase catalytic region KR PF08659.10 ACL97298.2 - 0.00017 21.6 0.1 0.0004 20.3 0.0 1.7 2 0 0 2 2 2 1 KR domain Glyco_transf_41 PF13844.6 ACL97299.1 - 3.7e-72 243.3 0.0 1.9e-41 142.0 0.0 2.0 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_2 PF07719.17 ACL97299.1 - 6.6e-10 38.3 16.2 0.13 12.4 0.2 5.9 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 ACL97299.1 - 3.4e-09 37.1 18.6 0.00086 19.8 3.7 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 ACL97299.1 - 3e-08 33.2 1.4 0.24 11.3 0.1 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 ACL97299.1 - 4.6e-08 33.1 24.7 3.8e-05 23.7 4.8 3.8 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 ACL97299.1 - 2.6e-05 23.8 0.1 0.0094 15.6 0.0 3.5 2 1 2 4 4 4 1 TPR repeat TPR_17 PF13431.6 ACL97299.1 - 3.4e-05 23.9 0.1 0.0072 16.6 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 ACL97299.1 - 8.1e-05 22.5 0.0 3.3 8.1 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 ACL97299.1 - 0.00059 20.4 10.7 0.00059 20.4 10.7 6.0 4 1 4 8 8 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 ACL97299.1 - 0.0012 19.4 44.5 0.029 15.2 1.5 7.1 4 1 4 8 8 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 ACL97299.1 - 0.0032 17.7 2.0 1.6 9.0 0.3 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 ACL97299.1 - 0.016 14.4 7.9 0.66 9.1 3.9 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat BTAD PF03704.17 ACL97299.1 - 0.16 12.4 17.5 3.5 8.1 0.2 4.2 1 1 2 3 3 3 0 Bacterial transcriptional activator domain DUF2267 PF10025.9 ACL97299.1 - 0.19 12.0 3.8 1.1 9.5 1.1 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) TPR_10 PF13374.6 ACL97299.1 - 3.4 7.7 16.4 14 5.7 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 ACL97299.1 - 3.5 8.0 19.3 0.074 13.3 0.7 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 ACL97299.1 - 5.1 7.9 9.9 39 5.2 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat ketoacyl-synt PF00109.26 ACL97300.1 - 7.9e-41 140.3 2.9 1.2e-40 139.7 2.9 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 ACL97300.1 - 5e-29 100.7 0.3 5e-29 100.7 0.3 2.3 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 ACL97300.1 - 5.2e-05 22.7 1.1 0.0039 16.6 1.0 2.2 1 1 1 2 2 2 2 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 ACL97300.1 - 0.074 13.5 0.1 0.57 10.7 0.0 2.5 3 0 0 3 3 3 0 Ketoacyl-synthetase C-terminal extension FabA PF07977.13 ACL97301.1 - 1.1e-52 177.4 0.0 1.3e-52 177.1 0.0 1.0 1 0 0 1 1 1 1 FabA-like domain SH3_4 PF06347.13 ACL97302.3 - 3.2e-36 122.9 5.0 9.5e-18 63.8 0.9 2.2 2 0 0 2 2 2 2 Bacterial SH3 domain YtxH PF12732.7 ACL97302.3 - 0.12 12.9 2.6 0.33 11.5 0.0 2.1 2 0 0 2 2 2 0 YtxH-like protein 2-Hacid_dh_C PF02826.19 ACL97303.2 - 2.4e-61 206.2 0.1 6.6e-61 204.8 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ACL97303.2 - 1.6e-32 112.0 0.0 2e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ACL97303.2 - 5.5e-07 29.9 0.0 1.2e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.22 ACL97303.2 - 0.00042 21.1 0.0 0.0011 19.8 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 ACL97303.2 - 0.00059 20.4 0.0 0.0035 17.9 0.0 2.4 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 ACL97303.2 - 0.014 15.0 0.0 0.075 12.6 0.0 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain XdhC_C PF13478.6 ACL97303.2 - 0.035 14.6 0.0 0.09 13.3 0.0 1.7 1 1 0 1 1 1 0 XdhC Rossmann domain Peptidase_S9 PF00326.21 ACL97304.1 - 8e-39 133.3 0.0 1.2e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 ACL97304.1 - 2.1e-15 56.6 0.4 1.1e-08 34.7 0.1 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 ACL97304.1 - 3.8e-11 42.9 0.0 8e-11 41.9 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 ACL97304.1 - 3.5e-10 39.9 0.1 9.1e-06 25.5 0.3 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 ACL97304.1 - 2e-08 34.2 0.0 2.9e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 ACL97304.1 - 2.2e-08 34.1 0.2 1.9e-05 24.4 0.2 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 ACL97304.1 - 2.1e-07 31.0 0.1 1.1e-05 25.4 0.1 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 ACL97304.1 - 2.7e-05 24.1 0.0 0.14 11.9 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase BAAT_C PF08840.11 ACL97304.1 - 0.00023 21.2 0.0 0.0036 17.3 0.0 2.1 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 ACL97304.1 - 0.00027 21.6 8.0 0.00027 21.6 8.0 3.3 3 1 0 3 3 3 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 ACL97304.1 - 0.00097 18.7 1.0 0.007 15.9 1.0 2.1 1 1 0 1 1 1 1 Esterase PHB depolymerase Chlorophyllase2 PF12740.7 ACL97304.1 - 0.0013 17.7 0.0 0.0029 16.6 0.0 1.5 1 0 0 1 1 1 1 Chlorophyllase enzyme AXE1 PF05448.12 ACL97304.1 - 0.002 16.9 0.1 0.031 13.0 0.1 2.4 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) LIP PF03583.14 ACL97304.1 - 0.084 12.2 0.6 3 7.1 0.4 2.2 2 0 0 2 2 2 0 Secretory lipase AcetylCoA_hyd_C PF13336.6 ACL97305.1 - 1.6e-39 135.3 0.0 2.4e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 ACL97305.1 - 3.1e-29 102.4 0.0 4.6e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain CitF PF04223.12 ACL97305.1 - 0.00021 20.3 0.0 0.00028 19.9 0.0 1.1 1 0 0 1 1 1 1 Citrate lyase, alpha subunit (CitF) CoA_trans PF01144.23 ACL97305.1 - 0.05 13.0 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Coenzyme A transferase Abhydrolase_1 PF00561.20 ACL97306.1 - 1.1e-27 97.3 0.4 4.7e-21 75.6 0.5 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ACL97306.1 - 2.2e-20 74.2 9.7 3.5e-20 73.6 9.7 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ACL97306.1 - 2.6e-20 72.7 0.2 6.8e-13 48.4 0.1 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 ACL97306.1 - 4.4e-06 26.4 0.1 0.00035 20.2 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 ACL97306.1 - 0.00024 20.9 0.0 0.013 15.3 0.0 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.20 ACL97306.1 - 0.00049 20.3 0.0 0.00071 19.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 ACL97306.1 - 0.0019 17.9 0.0 0.0085 15.8 0.0 2.0 2 0 0 2 2 2 1 Putative esterase FSH1 PF03959.13 ACL97306.1 - 0.0057 16.3 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.10 ACL97306.1 - 0.0079 16.3 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.21 ACL97306.1 - 0.011 15.3 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF915 PF06028.11 ACL97306.1 - 0.036 13.4 0.0 1.7 7.9 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_2 PF02230.16 ACL97306.1 - 0.048 13.4 0.0 33 4.2 0.0 3.0 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Ndr PF03096.14 ACL97306.1 - 0.21 10.3 0.0 0.34 9.5 0.0 1.3 1 0 0 1 1 1 0 Ndr family ThiF PF00899.21 ACL97307.2 - 6.1e-61 205.9 0.0 7.1e-61 205.7 0.0 1.0 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.6 ACL97307.2 - 0.0055 17.1 0.0 0.0094 16.4 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 ACL97307.2 - 0.0068 16.7 0.2 0.0068 16.7 0.2 1.9 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain DAO PF01266.24 ACL97307.2 - 0.012 15.2 0.1 0.012 15.2 0.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 ACL97307.2 - 0.029 14.4 0.0 0.056 13.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 ACL97307.2 - 0.083 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 ACL97307.2 - 0.21 10.8 3.4 0.31 10.2 3.4 1.2 1 0 0 1 1 1 0 FAD binding domain Ldh_1_N PF00056.23 ACL97307.2 - 1.8 8.6 4.5 1.1 9.3 0.2 2.2 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Proteasome PF00227.26 ACL97308.1 - 3.1e-22 79.0 1.6 8.7e-22 77.5 1.6 1.7 1 1 0 1 1 1 1 Proteasome subunit AAA_2 PF07724.14 ACL97309.1 - 2.6e-47 161.1 0.2 3.5e-37 128.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 ACL97309.1 - 7.6e-17 62.0 0.5 1.2e-06 29.0 0.0 3.1 2 1 1 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ACL97309.1 - 4.7e-09 36.4 0.4 4.1e-06 26.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.9 ACL97309.1 - 3.1e-08 33.6 1.8 4.1e-08 33.2 0.3 2.0 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.6 ACL97309.1 - 6.3e-07 29.9 6.3 3.5e-06 27.5 3.5 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ACL97309.1 - 2.2e-06 28.0 0.1 3.9e-05 23.9 0.1 2.4 1 1 0 1 1 1 1 AAA domain MCM PF00493.23 ACL97309.1 - 4.5e-06 25.9 0.0 0.0011 18.1 0.0 2.2 2 0 0 2 2 2 1 MCM P-loop domain Sigma54_activat PF00158.26 ACL97309.1 - 0.00014 21.7 0.0 0.058 13.1 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.6 ACL97309.1 - 0.00024 21.6 0.0 0.0006 20.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 ACL97309.1 - 0.00044 19.7 0.2 0.0094 15.3 0.0 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI CPT PF07931.12 ACL97309.1 - 0.0034 17.2 0.2 0.017 15.0 0.0 2.1 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein RuvB_N PF05496.12 ACL97309.1 - 0.0044 16.8 0.0 0.087 12.6 0.0 2.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TniB PF05621.11 ACL97309.1 - 0.0061 16.0 0.1 0.027 13.9 0.0 2.1 2 1 0 2 2 2 1 Bacterial TniB protein AAA_14 PF13173.6 ACL97309.1 - 0.0086 16.1 0.5 6.4 6.8 0.1 2.9 2 1 1 3 3 3 0 AAA domain IstB_IS21 PF01695.17 ACL97309.1 - 0.0089 15.8 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.6 ACL97309.1 - 0.0095 16.2 0.1 0.0095 16.2 0.1 2.1 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 ACL97309.1 - 0.011 15.9 0.2 0.04 14.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 ACL97309.1 - 0.016 14.9 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.12 ACL97309.1 - 0.047 13.6 0.2 0.56 10.1 0.0 2.5 2 1 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 ACL97309.1 - 0.048 13.4 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ACL97309.1 - 0.057 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 ACL97309.1 - 0.057 13.3 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 ACL97309.1 - 0.062 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 ACL97309.1 - 0.082 13.2 1.8 0.26 11.6 0.2 2.5 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 ACL97309.1 - 0.082 13.4 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Roc PF08477.13 ACL97309.1 - 0.093 13.0 0.0 0.42 10.8 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 ACL97309.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DEAD PF00270.29 ACL97309.1 - 0.14 11.9 0.0 5.9 6.6 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase DNA_binding_1 PF01035.20 ACL97310.1 - 1.9e-27 95.2 0.1 4.6e-27 94.0 0.1 1.7 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain HTH_18 PF12833.7 ACL97310.1 - 5.9e-15 55.3 1.3 9.8e-15 54.6 0.2 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AraC PF00165.23 ACL97310.1 - 4.1e-07 29.9 0.0 2.4e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family ACP_syn_III_C PF08541.10 ACL97310.1 - 0.084 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF2244 PF10003.9 ACL97311.1 - 5.1e-37 126.6 3.0 5.7e-37 126.5 3.0 1.0 1 0 0 1 1 1 1 Integral membrane protein (DUF2244) HhH-GPD PF00730.25 ACL97312.2 - 2.5e-18 66.5 0.0 3.6e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 ACL97312.2 - 4.1e-08 32.7 0.0 8.9e-08 31.6 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 ACL97312.2 - 1.2e-05 25.4 4.6 1.2e-05 25.4 4.6 2.0 2 0 0 2 2 2 1 Iron-sulfur binding domain of endonuclease III IMS_HHH PF11798.8 ACL97312.2 - 0.043 14.2 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif HHH_5 PF14520.6 ACL97312.2 - 0.05 14.2 0.0 0.13 12.9 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain GSH-S_ATP PF02955.16 ACL97313.2 - 0.019 14.4 0.0 0.045 13.1 0.0 1.6 1 1 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain RimK PF08443.11 ACL97313.2 - 0.028 14.0 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 RimK-like ATP-grasp domain PfkB PF00294.24 ACL97314.2 - 1.6e-40 139.3 1.3 2.6e-40 138.6 1.3 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase IGPD PF00475.18 ACL97315.1 - 4.5e-66 221.6 0.9 1.3e-65 220.1 0.4 1.7 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase VWA_3_C PF18571.1 ACL97315.1 - 0.017 14.9 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A C-terminal domain GATase PF00117.28 ACL97316.1 - 8.5e-19 68.1 0.0 9.7e-19 67.9 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 ACL97316.1 - 0.00017 21.5 0.0 0.02 14.8 0.0 2.0 2 0 0 2 2 2 2 SNO glutamine amidotransferase family Peptidase_C26 PF07722.13 ACL97316.1 - 0.00018 21.3 0.3 0.046 13.5 0.0 2.2 2 0 0 2 2 2 2 Peptidase C26 GATase_3 PF07685.14 ACL97316.1 - 0.00042 20.0 0.0 0.00062 19.4 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain His_biosynth PF00977.21 ACL97317.1 - 1.1e-75 254.1 3.9 1.2e-75 253.9 3.9 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.17 ACL97317.1 - 1.7e-09 37.2 1.2 0.00086 18.5 0.2 2.1 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) NMO PF03060.15 ACL97317.1 - 1.3e-05 24.8 8.7 0.012 15.0 0.4 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase TMP-TENI PF02581.17 ACL97317.1 - 0.00024 20.5 1.2 0.19 11.0 0.1 2.4 2 0 0 2 2 2 2 Thiamine monophosphate synthase DHO_dh PF01180.21 ACL97317.1 - 0.0015 17.8 1.0 0.67 9.1 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase ThiG PF05690.14 ACL97317.1 - 0.0033 16.8 4.4 0.28 10.4 0.2 2.2 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG Trp_syntA PF00290.20 ACL97317.1 - 0.0055 15.6 0.2 0.073 11.9 0.1 2.1 2 0 0 2 2 2 1 Tryptophan synthase alpha chain G3P_antiterm PF04309.12 ACL97317.1 - 0.025 14.0 2.1 0.63 9.4 0.2 2.2 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator IMPDH PF00478.25 ACL97317.1 - 0.17 10.8 2.8 3.7 6.4 0.1 2.1 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 ACL97318.1 - 1.9e-87 292.6 2.4 2.1e-87 292.4 2.4 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.17 ACL97318.1 - 0.00081 18.6 0.7 0.099 11.7 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) G3P_antiterm PF04309.12 ACL97318.1 - 0.0022 17.4 0.4 0.2 11.1 0.0 2.2 2 0 0 2 2 2 2 Glycerol-3-phosphate responsive antiterminator ThiG PF05690.14 ACL97318.1 - 0.0045 16.3 10.8 0.071 12.4 1.0 2.7 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG NMO PF03060.15 ACL97318.1 - 0.025 13.9 8.6 0.088 12.2 3.4 2.2 2 0 0 2 2 2 0 Nitronate monooxygenase PRA-PH PF01503.17 ACL97319.1 - 2.3e-17 63.2 0.3 2.7e-17 63.0 0.3 1.1 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 ACL97319.1 - 0.002 18.3 0.2 0.0049 17.0 0.1 1.6 2 0 0 2 2 2 1 MazG nucleotide pyrophosphohydrolase domain Smr PF01713.21 ACL97320.1 - 1.3e-21 76.7 0.1 2e-21 76.2 0.1 1.3 1 0 0 1 1 1 1 Smr domain MltA PF03562.17 ACL97321.1 - 9.3e-59 198.9 0.0 1.2e-58 198.6 0.0 1.1 1 0 0 1 1 1 1 MltA specific insert domain 3D PF06725.11 ACL97321.1 - 4.4e-22 78.0 0.3 1.2e-21 76.6 0.3 1.8 1 0 0 1 1 1 1 3D domain DUF3558 PF12079.8 ACL97321.1 - 0.15 12.0 3.3 0.24 11.4 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) Tim44 PF04280.15 ACL97322.2 - 4.6e-35 120.9 0.2 5.4e-35 120.6 0.2 1.1 1 0 0 1 1 1 1 Tim44-like domain DUF4440 PF14534.6 ACL97322.2 - 3.7e-05 24.1 1.3 7.6e-05 23.1 1.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 ACL97322.2 - 0.021 15.5 2.1 0.04 14.6 2.1 1.6 1 0 0 1 1 1 0 SnoaL-like domain SecB PF02556.14 ACL97323.1 - 1.5e-47 161.1 0.0 1.7e-47 160.8 0.0 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit SecB Response_reg PF00072.24 ACL97324.3 - 4e-26 91.4 0.1 1.2e-25 89.8 0.0 1.8 2 1 0 2 2 2 1 Response regulator receiver domain Trans_reg_C PF00486.28 ACL97324.3 - 9.9e-21 73.6 1.2 1.4e-20 73.1 0.4 1.6 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal DUF3310 PF11753.8 ACL97324.3 - 0.051 13.8 0.2 0.21 11.8 0.1 2.0 2 1 0 2 2 2 0 Protein of unknwon function (DUF3310) YkuD PF03734.14 ACL97325.1 - 1.2e-08 35.5 0.0 1.5e-08 35.2 0.0 1.1 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain Ala_racemase_N PF01168.20 ACL97326.1 - 4.9e-20 72.1 0.0 6.2e-20 71.8 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DUF2620 PF10941.8 ACL97326.1 - 0.025 14.7 0.1 0.8 9.9 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function DUF2620 TMP-TENI PF02581.17 ACL97327.2 - 2.1e-32 111.9 0.0 2.3e-32 111.8 0.0 1.0 1 0 0 1 1 1 1 Thiamine monophosphate synthase DUF3576 PF12100.8 ACL97329.3 - 4.9e-46 155.0 0.0 6.2e-46 154.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3576) tRNA-synt_1_2 PF13603.6 ACL97330.1 - 3e-66 222.5 0.0 4.6e-66 221.9 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1 PF00133.22 ACL97330.1 - 2e-64 218.0 0.0 4.6e-26 91.2 0.4 6.0 1 1 4 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 ACL97330.1 - 2.3e-29 102.3 0.0 2.2e-19 69.5 0.0 4.1 3 1 1 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 ACL97330.1 - 3.8e-17 62.7 0.0 9.7e-17 61.3 0.0 1.6 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1f PF01921.18 ACL97330.1 - 3.9e-06 26.0 0.0 0.09 11.7 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class I (K) tRNA-synt_1e PF01406.19 ACL97330.1 - 1.9e-05 24.2 0.0 0.086 12.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain DNA_ligase_ZBD PF03119.16 ACL97330.1 - 0.032 14.3 0.0 0.081 13.0 0.0 1.7 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain Zn-ribbon_8 PF09723.10 ACL97330.1 - 0.61 10.2 1.8 1.7 8.8 0.2 2.3 2 0 0 2 2 2 0 Zinc ribbon domain LptE PF04390.12 ACL97331.1 - 3.7e-07 30.8 0.6 5e-07 30.4 0.6 1.2 1 0 0 1 1 1 1 Lipopolysaccharide-assembly ABC_trans_aux PF03886.13 ACL97331.1 - 0.017 14.7 0.6 0.025 14.1 0.6 1.3 1 0 0 1 1 1 0 ABC-type transport auxiliary lipoprotein component Tgi2PP PF18250.1 ACL97331.1 - 0.085 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Effector immunity protein Tgi2PP DNA_pol3_delta PF06144.13 ACL97332.1 - 2.1e-05 24.4 0.0 2.7e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase III, delta subunit FUSC PF04632.12 ACL97332.1 - 0.0058 15.2 3.0 0.0058 15.2 3.0 1.4 2 0 0 2 2 2 1 Fusaric acid resistance protein family ParBc PF02195.18 ACL97333.2 - 7e-28 96.8 0.6 1.5e-27 95.7 0.6 1.6 1 0 0 1 1 1 1 ParB-like nuclease domain HTH_ParB PF17762.1 ACL97333.2 - 1.5e-15 56.7 0.2 4.3e-15 55.2 0.2 1.9 1 0 0 1 1 1 1 HTH domain found in ParB protein TrmB PF01978.19 ACL97333.2 - 0.058 13.3 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB KorB PF08535.10 ACL97333.2 - 0.061 13.4 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 KorB domain Soyouz_module PF14313.6 ACL97333.2 - 0.15 11.8 0.1 1.6 8.6 0.0 2.7 4 0 0 4 4 4 0 N-terminal region of Paramyxovirinae phosphoprotein (P) AAA_31 PF13614.6 ACL97334.1 - 2e-60 203.8 0.0 2.7e-60 203.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 ACL97334.1 - 3e-31 108.1 0.0 4.5e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 ACL97334.1 - 2.3e-13 50.2 0.0 4.4e-13 49.3 0.0 1.4 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 ACL97334.1 - 5e-11 42.5 0.1 7.5e-10 38.7 0.1 2.0 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.11 ACL97334.1 - 7e-11 41.9 0.2 2.5e-09 36.8 0.2 2.2 1 1 0 1 1 1 1 ATPase MipZ ParA PF10609.9 ACL97334.1 - 9.2e-09 35.1 0.7 6.4e-08 32.3 0.1 2.4 2 1 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase ArsA_ATPase PF02374.15 ACL97334.1 - 9.5e-07 28.3 0.1 1.8e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 Anion-transporting ATPase VirC1 PF07015.11 ACL97334.1 - 8.2e-05 22.0 0.1 0.00018 20.9 0.1 1.7 1 1 0 1 1 1 1 VirC1 protein MeaB PF03308.16 ACL97334.1 - 0.017 14.1 0.1 0.031 13.3 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FTHFS PF01268.19 ACL97334.1 - 0.06 11.5 0.1 0.096 10.9 0.1 1.2 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase CLP1_P PF16575.5 ACL97334.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop SRP54 PF00448.22 ACL97334.1 - 0.16 11.6 0.1 1.6 8.3 0.1 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain GidB PF02527.15 ACL97335.1 - 7e-41 139.6 0.0 8.7e-41 139.3 0.0 1.0 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G GIDA PF01134.22 ACL97336.2 - 1.1e-160 535.1 0.0 1.3e-160 534.8 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 ACL97336.2 - 6.4e-71 238.9 0.0 9.3e-71 238.3 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_binding_2 PF00890.24 ACL97336.2 - 1.9e-08 33.9 3.3 4.1e-05 22.9 1.4 2.5 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 ACL97336.2 - 1.4e-06 27.9 2.0 2.4e-06 27.2 2.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ACL97336.2 - 6.1e-05 22.4 0.3 0.00012 21.4 0.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ACL97336.2 - 0.00042 19.1 0.4 0.0071 15.1 0.3 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 ACL97336.2 - 0.0066 15.7 0.2 0.16 11.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ACL97336.2 - 0.014 14.7 0.1 0.027 13.8 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 ACL97336.2 - 0.016 15.8 0.3 0.038 14.5 0.3 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ACL97336.2 - 0.018 14.6 4.8 1.3 8.5 0.4 2.8 3 0 0 3 3 3 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ACL97336.2 - 0.028 13.5 0.6 0.086 11.9 0.4 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 ACL97336.2 - 0.2 10.9 0.6 1.9 7.7 0.2 2.1 2 0 0 2 2 2 0 Thi4 family NAD_binding_8 PF13450.6 ACL97336.2 - 1.7 9.0 5.0 0.36 11.1 1.2 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain MnmE_helical PF12631.7 ACL97337.3 - 5.6e-50 170.4 0.1 7.4e-50 170.0 0.1 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 ACL97337.3 - 4.3e-38 130.2 0.1 1e-37 129.0 0.1 1.7 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 ACL97337.3 - 3.2e-19 69.1 0.0 8.2e-19 67.8 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ACL97337.3 - 8.4e-09 35.1 0.0 1.3e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 ACL97337.3 - 1.3e-05 25.2 0.0 0.055 13.4 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase GCV_T PF01571.21 ACL97337.3 - 4.3e-05 23.0 0.0 8.6e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain cobW PF02492.19 ACL97337.3 - 5.7e-05 22.8 0.2 0.0029 17.2 0.0 2.3 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 ACL97337.3 - 9.5e-05 22.7 0.5 0.00039 20.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 ACL97337.3 - 0.00054 20.0 0.0 0.00085 19.4 0.0 1.3 1 0 0 1 1 1 1 Dynamin family AAA_18 PF13238.6 ACL97337.3 - 0.017 15.7 0.0 0.067 13.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Arf PF00025.21 ACL97337.3 - 0.038 13.4 0.0 0.43 10.0 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family ABC_tran PF00005.27 ACL97337.3 - 0.078 13.5 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter TPR_10 PF13374.6 ACL97337.3 - 0.11 12.4 4.9 5.3 7.1 0.6 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_16 PF13191.6 ACL97337.3 - 2.7 8.3 7.7 0.43 10.9 1.4 2.7 1 1 1 2 2 2 0 AAA ATPase domain DLH PF01738.18 ACL97339.1 - 6.6e-58 195.8 0.5 7.4e-58 195.7 0.5 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 ACL97339.1 - 4.4e-05 22.9 0.6 0.0013 18.1 0.1 2.3 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 ACL97339.1 - 0.00069 19.2 2.0 0.014 14.9 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family BAAT_C PF08840.11 ACL97339.1 - 0.0035 17.3 0.8 0.35 10.8 0.1 2.2 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 ACL97339.1 - 0.091 13.3 4.2 0.25 11.9 0.4 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family ADH_zinc_N PF00107.26 ACL97340.1 - 5e-28 97.7 0.3 5e-28 97.7 0.3 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ACL97340.1 - 3.3e-23 83.2 0.1 6.7e-23 82.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ACL97340.1 - 2.8e-12 46.5 0.1 7e-12 45.2 0.1 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 ACL97340.1 - 0.0021 17.9 0.1 0.0055 16.6 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Rho_RNA_bind PF07497.12 ACL97341.2 - 1.8e-30 104.6 0.0 3.1e-30 103.8 0.0 1.4 1 0 0 1 1 1 1 Rho termination factor, RNA-binding domain ATP-synt_ab PF00006.25 ACL97341.2 - 7e-24 84.7 0.1 1.3e-23 83.8 0.1 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Rho_N PF07498.12 ACL97341.2 - 1.9e-16 59.7 0.7 1.4e-15 56.9 0.5 2.5 2 0 0 2 2 2 1 Rho termination factor, N-terminal domain AAA_22 PF13401.6 ACL97341.2 - 0.00062 20.1 0.0 0.027 14.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 ACL97341.2 - 0.0021 18.0 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 NACHT domain OB_RNB PF08206.11 ACL97341.2 - 0.0028 17.3 0.0 0.0059 16.3 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease B OB domain AAA_16 PF13191.6 ACL97341.2 - 0.019 15.3 0.0 0.1 13.0 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 ACL97341.2 - 0.021 15.2 0.0 0.057 13.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 ACL97341.2 - 0.052 13.1 0.0 0.22 11.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 ACL97341.2 - 0.054 13.5 0.1 0.59 10.2 0.0 2.6 3 1 0 3 3 2 0 AAA domain ATPase_2 PF01637.18 ACL97341.2 - 0.056 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Terminase_GpA PF05876.12 ACL97341.2 - 0.068 11.7 0.0 4.6 5.7 0.0 2.1 1 1 1 2 2 2 0 Phage terminase large subunit (GpA) UPF0093 PF03653.13 ACL97342.1 - 2.7e-52 176.9 1.6 3.1e-52 176.7 1.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0093) Pox_A14 PF05767.12 ACL97342.1 - 0.0051 16.9 1.1 0.17 12.0 0.0 2.6 2 1 0 2 2 2 1 Poxvirus virion envelope protein A14 DUF3149 PF11346.8 ACL97342.1 - 0.099 12.3 0.1 0.099 12.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) Ferrochelatase PF00762.19 ACL97343.1 - 2.6e-101 338.9 0.0 2.9e-101 338.7 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase URO-D PF01208.17 ACL97344.2 - 2.4e-101 339.4 0.0 2.9e-101 339.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) CPBP PF02517.16 AGJ94599.2 - 1.9e-11 44.2 6.9 1.9e-11 44.2 6.9 2.5 1 1 0 2 2 2 1 CPBP intramembrane metalloprotease DUF2749 PF10907.8 AGJ94599.2 - 0.052 13.7 0.4 0.052 13.7 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2749) Trypsin_2 PF13365.6 AGJ94600.2 - 1.2e-14 55.4 0.0 2.3e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 AGJ94600.2 - 4.8e-05 23.3 0.0 0.00073 19.4 0.0 2.3 2 1 0 2 2 2 1 Trypsin DUF4129 PF13559.6 AGJ94601.1 - 0.0018 18.5 14.2 0.03 14.6 14.2 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4129) MRAP PF15183.6 AGJ94601.1 - 0.16 11.9 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family TPR_10 PF13374.6 AGJ94604.1 - 5 7.1 12.0 1.2 9.1 1.4 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat AHSA1 PF08327.11 AGJ94606.1 - 1e-11 45.2 0.4 1.2e-11 44.9 0.4 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 AGJ94606.1 - 0.0014 18.9 4.8 0.002 18.4 4.8 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport HD_2 PF12917.7 AGJ94607.1 - 9.1e-08 32.1 0.0 1.4e-06 28.2 0.0 2.1 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 AGJ94607.1 - 7.9e-05 22.9 0.2 0.00017 21.8 0.2 1.7 1 1 0 1 1 1 1 HD domain HD_3 PF13023.6 AGJ94607.1 - 0.00034 20.6 0.0 0.00044 20.2 0.0 1.2 1 0 0 1 1 1 1 HD domain MFS_2 PF13347.6 AGJ94608.1 - 0.061 11.9 0.0 0.079 11.5 0.0 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein QLQ PF08880.11 AGJ94608.1 - 0.14 12.0 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 QLQ DUF2206 PF09971.9 AGJ94608.1 - 0.14 10.8 0.0 0.26 10.0 0.0 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2206) MFS_2 PF13347.6 AGJ94609.1 - 1.6e-29 102.7 36.9 3.7e-29 101.5 36.9 1.5 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 AGJ94609.1 - 0.032 13.2 66.1 0.035 13.0 61.7 2.1 1 1 1 2 2 2 0 Major Facilitator Superfamily Poly_export PF02563.16 AGJ94611.1 - 0.0059 16.8 0.1 3.5 7.9 0.0 2.4 2 0 0 2 2 2 2 Polysaccharide biosynthesis/export protein DUF1251 PF06856.11 AGJ94611.1 - 0.075 12.8 2.0 0.22 11.3 1.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1251) FTR_C PF02741.15 AGJ94611.1 - 0.085 12.9 2.5 0.16 12.0 1.9 1.7 1 1 0 1 1 1 0 FTR, proximal lobe DUF5133 PF17196.4 AGJ94611.1 - 0.31 11.2 0.2 0.31 11.2 0.2 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF5133) Shadoo PF14999.6 AGJ94611.1 - 5.2 7.2 9.5 2.6 8.2 0.6 2.1 1 1 1 2 2 2 0 Shadow of prion protein, neuroprotective DUF3253 PF11625.8 AGJ94612.2 - 8.3e-22 77.2 0.1 9.5e-22 77.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3253) LEH PF07858.12 AGJ94613.1 - 1.9e-18 66.8 0.1 2.3e-18 66.5 0.1 1.1 1 0 0 1 1 1 1 Limonene-1,2-epoxide hydrolase catalytic domain SnoaL_2 PF12680.7 AGJ94613.1 - 4.8e-17 62.5 0.7 5.9e-17 62.2 0.7 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 AGJ94613.1 - 2e-05 24.4 0.1 0.00013 21.8 0.1 1.9 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase Phage_connect_1 PF05135.13 AGJ94618.1 - 9.4e-10 38.9 0.0 1.1e-09 38.7 0.0 1.1 1 0 0 1 1 1 1 Phage gp6-like head-tail connector protein DUF3493 PF11998.8 AGJ94620.1 - 0.064 13.4 0.4 4.5 7.5 0.0 2.3 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 DUF2834 PF11196.8 AGJ94620.1 - 0.071 13.5 0.8 0.12 12.7 0.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2834) FPN1 PF06963.12 AGJ94620.1 - 0.096 11.2 2.0 3.2 6.2 0.1 2.0 2 0 0 2 2 2 0 Ferroportin1 (FPN1) DUF4096 PF13340.6 AGJ94621.1 - 5.8e-21 74.5 4.2 1.3e-20 73.3 1.3 2.0 2 0 0 2 2 2 1 Putative transposase of IS4/5 family (DUF4096) TetR_C_20 PF17925.1 AGJ94621.1 - 0.0085 16.4 1.7 0.011 16.0 1.7 1.2 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain EVI2A PF05399.11 AGJ94621.1 - 0.018 14.6 0.2 0.026 14.1 0.2 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) NrsF PF06532.11 AGJ94624.1 - 1.4e-34 119.7 32.5 1.6e-34 119.5 32.5 1.0 1 0 0 1 1 1 1 Negative regulator of sigma F DUF3918 PF13056.6 AGJ94624.1 - 0.16 11.6 0.2 0.35 10.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) SMC_ScpB PF04079.16 AGJ94626.1 - 0.095 12.3 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB DUF1908 PF08926.11 AHI88514.1 - 0.18 10.9 0.0 0.22 10.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) UDPG_MGDP_dh_N PF03721.14 AHI88523.1 - 6e-10 39.0 0.0 6e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 AHI88523.1 - 0.0069 16.9 0.0 0.007 16.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 AHI88523.1 - 0.059 12.6 0.1 0.059 12.6 0.1 1.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 AHI88523.1 - 0.068 13.1 0.0 0.068 13.1 0.0 1.0 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.9 AHI88523.1 - 0.073 12.9 0.0 0.073 12.9 0.0 1.0 1 0 0 1 1 1 0 Rossmann-like domain Glyco_trans_4_4 PF13579.6 AHI88524.1 - 1.4e-24 87.3 3.3 1.4e-24 87.3 3.3 2.3 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 AHI88524.1 - 2.3e-16 60.4 0.4 4.8e-16 59.4 0.3 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 AHI88524.1 - 7.3e-15 54.9 0.0 1.2e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AHI88524.1 - 1.6e-14 54.2 0.2 3.2e-14 53.3 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 AHI88524.1 - 0.11 12.9 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 AHI88525.1 - 0.0062 16.6 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 DUF2909 PF11137.8 AHI88530.1 - 0.027 14.4 0.4 0.027 14.4 0.4 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2909) DUF4131 PF13567.6 AHI88531.1 - 0.07 12.8 0.6 0.074 12.7 0.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) RhaT PF06379.12 AHI88534.1 - 0.003 16.8 1.5 0.0033 16.7 1.5 1.1 1 0 0 1 1 1 1 L-rhamnose-proton symport protein (RhaT) Bacteriocin_IIc PF10439.9 AHI88535.1 - 0.043 13.9 29.8 7.7 6.7 29.8 2.1 1 1 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_Omp PF13488.6 AHI88535.1 - 0.58 10.2 39.6 0.97 9.5 22.8 2.4 1 1 0 2 2 2 0 Glycine zipper MccV PF17508.2 AHI88535.1 - 1.6 9.4 16.1 2.1 8.9 5.9 2.3 1 1 1 2 2 2 0 Microcin V bacteriocin Bacteriocin_IIc PF10439.9 AHI88536.1 - 0.011 15.9 28.3 3.1 8.0 28.3 2.1 1 1 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide L_biotic_typeA PF04604.13 AHI88536.1 - 0.59 10.0 0.0 0.59 10.0 0.0 2.3 3 0 0 3 3 3 0 Type-A lantibiotic TraT PF05818.12 AHI88536.1 - 1.9 8.1 9.5 2.8 7.6 9.5 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein LPAM_2 PF13627.6 AHI88541.1 - 0.095 12.6 1.3 0.22 11.4 1.3 1.7 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site DUF3292 PF11696.8 AHI88541.1 - 0.39 9.0 5.0 0.45 8.8 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DUF1206 PF06724.11 AHI88541.1 - 0.75 9.9 6.2 0.14 12.3 1.7 2.0 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1206) MGC-24 PF05283.11 AHI88541.1 - 2 8.9 5.7 2.3 8.7 5.7 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Leu_leader PF08054.11 AHI88551.1 - 0.041 13.5 0.1 0.069 12.8 0.1 1.4 1 0 0 1 1 1 0 Leucine operon leader peptide DUF2147 PF09917.9 AHI88552.1 - 1e-14 55.1 0.0 1.2e-14 54.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2147) Calpain_III PF01067.22 AHI88552.1 - 0.016 15.5 0.0 0.019 15.2 0.0 1.1 1 0 0 1 1 1 0 Calpain large subunit, domain III ACC_epsilon PF13822.6 AHI88552.1 - 0.61 10.8 6.7 1 10.1 0.1 2.5 3 0 0 3 3 3 0 Acyl-CoA carboxylase epsilon subunit DUF4148 PF13663.6 AHI88552.1 - 0.99 9.6 3.8 1 9.6 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) zf-RRN7 PF11781.8 AHI88553.1 - 0.026 14.2 0.3 0.03 14.0 0.3 1.1 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DUF1761 PF08570.10 AHI88556.1 - 1.1e-21 77.4 10.8 1.2e-21 77.2 10.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) TusA PF01206.17 AHI88560.1 - 1.1e-16 60.4 0.0 1.2e-16 60.2 0.0 1.0 1 0 0 1 1 1 1 Sulfurtransferase TusA DUF3454 PF11936.8 AHI88570.1 - 0.71 10.3 5.3 0.24 11.8 2.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3454) MgtE PF01769.16 AHI88579.1 - 0.048 14.0 1.9 0.055 13.8 1.9 1.0 1 0 0 1 1 1 0 Divalent cation transporter DUF5337 PF17272.2 AHI88579.1 - 0.13 12.1 11.6 0.15 11.9 11.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5337) HTH_17 PF12728.7 AHI88580.1 - 4.5e-07 29.9 0.1 6.5e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HicA_toxin PF07927.12 AHI88586.1 - 0.0042 17.1 0.0 0.0054 16.7 0.0 1.3 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, DUF2157 PF09925.9 AHI88587.1 - 0.014 15.2 0.6 0.016 15.0 0.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Phage_holin_3_6 PF07332.11 AHI88587.1 - 0.016 15.2 1.0 0.018 15.1 1.0 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III TMEM238 PF15125.6 AHI88587.1 - 0.066 13.4 8.4 0.077 13.2 8.4 1.1 1 0 0 1 1 1 0 TMEM238 protein family DUF3318 PF11780.8 AHI88587.1 - 0.14 12.1 0.6 0.15 12.0 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) TrbC PF04956.13 AHI88587.1 - 0.57 10.4 5.4 1.5 9.1 0.2 2.0 1 1 1 2 2 2 0 TrbC/VIRB2 family DUF2583 PF10762.9 AHI88587.1 - 4.8 7.7 7.9 1.8 9.0 1.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2583) Leu_leader PF08054.11 AHI88588.1 - 0.34 10.5 1.5 0.36 10.5 0.0 1.8 2 0 0 2 2 2 0 Leucine operon leader peptide DUF4131 PF13567.6 AHI88588.1 - 0.69 9.5 12.0 0.97 9.1 3.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF3325 PF11804.8 AHI88588.1 - 2.4 8.4 19.1 23 5.2 14.8 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3325) MarR_2 PF12802.7 AHI88592.1 - 2.9e-14 52.7 0.4 2.9e-14 52.7 0.4 2.8 2 1 1 3 3 2 1 MarR family MarR PF01047.22 AHI88592.1 - 6.9e-13 48.3 0.1 4.3e-12 45.8 0.0 2.3 2 0 0 2 2 2 1 MarR family Acetyltransf_1 PF00583.25 AHI88592.1 - 1.1e-09 38.6 0.0 1.9e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family HTH_27 PF13463.6 AHI88592.1 - 8.8e-08 32.5 0.4 5.8e-07 29.9 0.0 2.5 3 0 0 3 3 3 1 Winged helix DNA-binding domain Acetyltransf_7 PF13508.7 AHI88592.1 - 3e-07 30.8 0.0 6.3e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HTH_20 PF12840.7 AHI88592.1 - 9.6e-07 28.8 1.4 2.4e-06 27.5 0.9 2.0 1 1 1 2 2 2 1 Helix-turn-helix domain Acetyltransf_10 PF13673.7 AHI88592.1 - 2.1e-06 27.7 0.0 5e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Rrf2 PF02082.20 AHI88592.1 - 2.8e-06 27.6 0.1 0.0014 18.9 0.0 2.8 2 0 0 2 2 2 1 Transcriptional regulator Fe_dep_repress PF01325.19 AHI88592.1 - 5.2e-06 26.6 0.0 4.6e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain HTH_24 PF13412.6 AHI88592.1 - 8.6e-06 25.2 0.1 3.7e-05 23.2 0.0 2.1 2 0 0 2 2 1 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 AHI88592.1 - 3.6e-05 23.5 3.1 0.00014 21.6 0.4 2.5 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_Crp_2 PF13545.6 AHI88592.1 - 5.5e-05 23.1 0.9 0.00012 22.0 0.2 2.0 2 0 0 2 2 1 1 Crp-like helix-turn-helix domain GntR PF00392.21 AHI88592.1 - 5.6e-05 22.7 1.1 0.00015 21.3 0.4 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family TrmB PF01978.19 AHI88592.1 - 0.0001 22.1 0.1 0.0022 17.9 0.0 2.6 1 1 1 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.20 AHI88592.1 - 0.00062 19.6 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family HemN_C PF06969.16 AHI88592.1 - 0.00066 19.7 0.5 0.0063 16.5 0.1 2.9 3 1 0 3 3 2 1 HemN C-terminal domain Acetyltransf_6 PF13480.7 AHI88592.1 - 0.0049 17.0 0.5 0.011 15.9 0.1 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 AHI88592.1 - 0.0057 16.6 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein HTH_DeoR PF08220.12 AHI88592.1 - 0.013 15.3 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_1 PF00126.27 AHI88592.1 - 0.044 13.8 0.2 0.17 11.9 0.2 2.1 1 1 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family HxlR PF01638.17 AHI88592.1 - 0.052 13.4 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 HxlR-like helix-turn-helix HTH_11 PF08279.12 AHI88592.1 - 0.054 13.4 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 HTH domain Crp PF00325.20 AHI88592.1 - 0.11 12.2 0.1 0.35 10.5 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family HTH_AsnC-type PF13404.6 AHI88592.1 - 0.14 12.0 1.0 0.53 10.2 0.1 2.5 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain DprA_WH PF17782.1 AHI88592.1 - 0.16 12.1 7.3 0.18 12.0 3.4 2.6 2 1 1 3 3 2 0 DprA winged helix domain CHASE3 PF05227.13 AHI88592.1 - 0.16 11.8 0.1 0.16 11.8 0.1 1.7 2 0 0 2 2 1 0 CHASE3 domain TFIIE_alpha PF02002.17 AHI88592.1 - 0.18 11.7 0.0 0.74 9.7 0.0 1.9 2 0 0 2 2 2 0 TFIIE alpha subunit TauE PF01925.19 AHI88596.1 - 0.085 12.5 7.6 0.1 12.2 7.6 1.1 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE LTXXQ PF07813.12 AHI88600.1 - 1.2e-15 58.0 3.3 1.9e-15 57.4 3.3 1.3 1 0 0 1 1 1 1 LTXXQ motif family protein Metal_resist PF13801.6 AHI88600.1 - 2.2 8.5 10.3 1.4 9.2 0.7 3.1 2 1 1 3 3 3 0 Heavy-metal resistance # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Caulobacter_crescentus_NA1000-ASM2200v1/GCA_000022005.1_ASM2200v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Caulobacter_crescentus_NA1000-ASM2200v1/GCA_000022005.1_ASM2200v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Caulobacter_crescentus_NA1000-ASM2200v1/GCA_000022005.1_ASM2200v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Bacteria/Caulobacter_crescentus_NA1000-ASM2200v1/GCA_000022005.1_ASM2200v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 02:24:19 2019 # [ok]